<210>  5218
<211>  5108
<212>  DNA
<213>  Homo sapiens

<400>  5218
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgcttaga tttgttgaca gcggtttcct ggagtgctgt   1980

cttgagaacg attctgagga ggctcagcaa gaaagagtgt ttcagttgat tgggtgtgtc   2040

tgtcatggag aaggaactca agctcttgga ctcaccgagg cagtaaaagt accatatcct   2100

gtgtttgaat caaacccgga gttcttgtat gtggaaggct tgccagaggg gattcccttc   2160

cgaagcccta cctggtttgg aattccacga cttgaaagga tcgtccgcgg gagtaataaa   2220

atcaagttcg ttgttaaaaa acctgaacta gttatttcct acttgcctcc tgggatggct   2280

agtaaaataa acactaaagc tttgcagtcc cccaaaagac cacgaagtcc tgggagtaat   2340

tcaaaggttc ctgaaattga ggtcaccgtg gaaggcccta ataacaacaa tcctcaaacc   2400

tcagctgttc gaaccccgac ccagactaac ggttctaacg ttcccttcaa gccacgaggg   2460

agagagtttt cctttgaggc ctggaatgcc aaaatcacgg acctaaaaca gaaagttgaa   2520

aatctcttca atgagaaatg tggggaagct cttggcctta aacaagctgt gaaggtgccg   2580

ttcgcgttat ttgagtcttt cccggaagac ttttatgtgg aaggcttacc tgagggtgtg   2640

ccattccgaa gaccatcgac ttttggcatt ccgaggctgg agaagatact cagaaacaaa   2700

gccaaaatta agttcatcat taaaaagccc gaaatgtttg agacggcgat taaggagagc   2760

acctcctcta agagccctcc cagaaaaata aattcatcac ccaatgttaa tactactgca   2820

tcaggtgttg aagaccttaa catcattcag gtgacaattc cagatgatga taatgaaaga   2880

ctctcgaaag ttgaaaaagc tagacagcta agagaacaag tgaatgacct ctttagtcgg   2940

aaatttggtg aagctattgg tatgggtttt cctgtgaaag ttccctacag gaaaatcaca   3000

attaaccctg gctgtgtggt ggttgatggc atgcccccgg gggtgtcctt caaagccccc   3060

agctacctgg aaatcagctc catgagaagg atcttagact ctgccgagtt tatcaaattc   3120

acggtcatta gaccatttcc aggacttgtg attaataacc agctggttga tcagagtgag   3180

tcagaaggcc ccgtgataca agaatcagct gaaccaagcc agttggaagt tccagccaca   3240

gaaggtaaaa ggacctcttc cctcctaggg taaatcagct tctgtgtcag ggatgctgtg   3300

tggtgtccat ctgaaccccc tgcatacgcg tagctaatgt gatctcccca ctttcacata   3360

agatggtggc cctgccttca gggaatgtgg gagccaggtg ggagccttcc cggatattta   3420

agctagaaga ttctacaggg agattctcct tggatcaata tatgtctctc agtcaaagat   3480

gtaaaagcac ttttgcctta aaaagaatgt tctgtttcta aatagagtca acgttgtcct   3540

cctcattgga attcactatg agtcagaatc attagactga cttttttttt tccatagtaa   3600

tagtattttg cagagtctca cagagctgca gatcttttgt tcatcttgca gagttaacaa   3660

gtctgatcct gttagtccag atttcttaaa tttggccaag ttataatagg agcagtagct   3720

tgagacccga agtcaggaaa ctttgacaat ggattttttt ttttaatcca gagacttgta   3780

ctggaatttg ccttaccctg tcagctcatg gacttaaggt ttcatcccgc tttatgagtg   3840

cttctgaatc caagtcattg ttacctgaat ttgcaaatta agttgtgata ttcgtgactg   3900

ttaaattcct gtaattagat taacctcttt gcttgcttgt ttgttttctc tcctatttta   3960

gcttaaagta tcagtggttg agaagagctt ttcggacctg ttactacccc aagctgtgta   4020

atatacttgt ataacagaaa taccttctat acaaaccttt ttttctactt ttagatagaa   4080

atgtctactt tttcagcagt tctgtgaatt aaagagcaga gtgactgtgg gtctggaatg   4140

gctggtgtac ttgggaatgt actatcagga ttttacagca atgctgggaa atgacaggga   4200

aaatgacagg aatgaatctc accagatttt ttatgtactc agcagagcct tgagttacgg   4260

tgtttatttt ccaatcaagt gaagatatct cctacttctc ctactggaac atctcagctt   4320

ctgcagtgaa gaaaaattcc tgtgatagtt cagttcttta gtttttctat ttgaaaaaaa   4380

aaaatcattt aaatgatcct ttgttcacgg ctctccttaa tgactgagtg aacagttcct   4440

atctgtatat ttgactaaac cttttcctaa gctatctctc atggttccta tgttttttta   4500

tcataattaa aagcaaaacc atctggatca cctaacagtc agaggtcagt atctcagcgt   4560

gtgaattata gaggaaatac agagagaacc tcttccactt ttacttttcg tccaaataaa   4620

atgcatggtg taccagaagt tgaagatcgg gttgaggatt ggggctagct cgatgacact   4680

aaggccccaa catcgcggga cctgctgtgg cgcggattct taggaacgct gttctagccg   4740

gccccctctc caggggtcgc cgtggccggc attatttcct agttcttctt gtaaccctga   4800

ggtgccagcg cggggagtga ggaggggtca gggggctaag gatgcaacct ctgacgttct   4860

gcgccttcct aggagagtct tacatgtgtt gagatttcac aagcaatgcg agttgtaaaa   4920

taccagctct acaagaagct aggctctgtg acggcatagt tttcagtagc tttatcacaa   4980

tattcacaat ggagaattat atgacatggt agcagaaata ggccctttta tgtgttgctt   5040

ctattttacc tcaaattgta gatatagggt aatcaataaa atccatccat gcctttcaca   5100

cactaagt                                                            5108


<210>  5219
<211>  563
<212>  PRT
<213>  Homo sapiens

<400>  5219

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala 



<210>  5220
<211>  3996
<212>  DNA
<213>  Homo sapiens

<400>  5220
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggaagccac cattcttcag    960

agggcaatga aggcacagaa atggaagtac cagcagaaga ttctactcaa catgtccctt   1020

cagaaacaag tgaggaccct gaagttgagg tgactattga agatgatgat tattctccac   1080

cgtctaagag accaaaggcc aatgagctac cgcagccacc agtcccggaa cccgccaatg   1140

ctgggaagcg gaaagtgagg gagttcaact tcgagaaatg gaatgctcgc atcactgatc   1200

tacgtaaaca agttgaagaa ttgtttgaaa ggaaatatgc tcaagccata aaagccaaag   1260

gtccggtgac gatcccgtac cctcttttcc agtctcatgt tgaagatctt tatgtagaag   1320

gacttcctga aggaattcct tttagaaggc catctactta cggaattcct cgcctggaga   1380

ggatattact tgcaaaggaa aggattcgtt ttgtgattaa gaaacatgag cttctgaatt   1440

caacacgtga agatttacag cttgataagc cagcttcagg agtaaaggaa gaatggtatg   1500

ccagaatcac taaattaaga aagatggtgg atcagctttt ctgcaaaaaa tttgcggaag   1560

ccttggggag cactgaagcc aaggctgtac cgtaccaaaa atttgaggca cacccgaatg   1620

atctgtacgt ggaaggactg ccagaaaaca ttcctttccg aagtccctca tggtatggaa   1680

tcccaaggct ggaaaaaatc attcaagtgg gcaatcgaat taaatttgtt attaaaagac   1740

cagaacttct gactcacagt accactgaag ttactcagcc aagaacgaat acaccagtca   1800

aagaagattg gaatgtcaga attaccaagc tacggaagca agtggaagag atttttaatt   1860

tgaaatttgc tcaagctctt ggactcaccg aggcagtaaa agtaccatat cctgtgtttg   1920

aatcaaaccc ggagttcttg tatgtggaag gcttgccaga ggggattccc ttccgaagcc   1980

ctacctggtt tggaattcca cgacttgaaa ggatcgtccg cgggagtaat aaaatcaagt   2040

tcgttgttaa aaaacctgaa ctagttattt cctacttgcc tcctgggatg gctagtaaaa   2100

taaacactaa agctttgcag tcccccaaaa gaccacgaag tcctgggagt aattcaaagg   2160

ttcctgaaat tgaggtcacc gtggaaggcc ctaataacaa caatcctcaa acctcagctg   2220

ttcgaacccc gacccagact aacggttcta acgttccctt caagccacga gggagagagt   2280

tttcctttga ggcctggaat gccaaaatca cggacctaaa acagaaagtt gaaaatctct   2340

tcaatgagaa atgtggggaa gctcttggcc ttaaacaagc tgtgaaggtg ccgttcgcgt   2400

tatttgagtc tttcccggaa gacttttatg tggaaggctt acctgagggt gtgccattcc   2460

gaagaccatc gacttttggc attccgaggc tggagaagat actcagaaac aaagccaaaa   2520

ttaagttcat cattaaaaag cccgaaatgt ttgagacggc gattaaggag agcacctcct   2580

ctaagagccc tcccagaaaa ataaattcat cacccaatgt taatactact gcatcaggtg   2640

ttgaagacct taacatcatt caggtgacaa ttccagatga tgataatgaa agactctcga   2700

aagttgaaaa agctagacag ctaagagaac aagtgaatga cctctttagt cggaaatttg   2760

gtgaagctat tggtatgggt tttcctgtga aagttcccta caggaaaatc acaattaacc   2820

ctggctgtgt ggtggttgat ggcatgcccc cgggggtgtc cttcaaagcc cccagctacc   2880

tggaaatcag ctccatgaga aggatcttag actctgccga gtttatcaaa ttcacggtca   2940

ttagaccatt tccaggactt gtgattaata accagctggt tgatcagagt gagtcagaag   3000

gccccgtgat acaagaatca gctgaaccaa gccagttgga agttccagcc acagaagaaa   3060

taaaagagac tgatggaagc tctcagatca agcaagaacc agaccccacg tggtagacct   3120

cttccctcct aggagccttg agttacggtg tttattttcc aatcaagtga agatatctcc   3180

tacttctcct actggaacat ctcagcttct gcagtgaaga aaaattcctg tgatagttca   3240

gttctttagt ttttctattt gaaaaaaaaa aatcatttaa atgatccttt gttcacggct   3300

ctccttaatg actgagtgaa cagttcctat ctgtatattt gactaaacct tttcctaagc   3360

tatctctcat ggttcctatg tttttttatc ataattaaaa gcaaaaccat ctggatcacc   3420

taacagtcag aggtcagtat ctcagcgtgt gaattataga ggaaatacag agagaacctc   3480

ttccactttt acttttcgtc caaataaaat gcatggtgta ccagaagttg aagatcgggt   3540

tgaggattgg ggctagctcg atgacactaa ggccccaaca tcgcgggacc tgctgtggcg   3600

cggattctta ggaacgctgt tctagccggc cccctctcca ggggtcgccg tggccggcat   3660

tatttcctag ttcttcttgt aaccctgagg tgccagcgcg gggagtgagg aggggtcagg   3720

gggctaagga tgcaacctct gacgttctgc gccttcctag gagagtctta catgtgttga   3780

gatttcacaa gcaatgcgag ttgtaaaata ccagctctac aagaagctag gctctgtgac   3840

ggcatagttt tcagtagctt tatcacaata ttcacaatgg agaattatat gacatggtag   3900

cagaaatagg cccttttatg tgttgcttct attttacctc aaattgtaga tatagggtaa   3960

tcaataaaat ccatccatgc ctttcacaca ctaagt                             3996


<210>  5221
<211>  952
<212>  PRT
<213>  Homo sapiens

<400>  5221

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr 
225                 230                 235                 240


Glu Met Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu 
                245                 250                 255


Thr Ser Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr 
            260                 265                 270


Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro 
        275                 280                 285


Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn 
    290                 295                 300


Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu 
305                 310                 315                 320


Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro 
                325                 330                 335


Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr 
            340                 345                 350


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr 
        355                 360                 365


Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg 
    370                 375                 380


Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu 
385                 390                 395                 400


Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg 
                405                 410                 415


Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe 
            420                 425                 430


Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys 
        435                 440                 445


Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn 
    450                 455                 460


Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys 
465                 470                 475                 480


Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu 
                485                 490                 495


Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr 
            500                 505                 510


Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln 
        515                 520                 525


Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr 
    530                 535                 540


Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe 
545                 550                 555                 560


Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr 
                565                 570                 575


Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn Lys 
            580                 585                 590


Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro 
        595                 600                 605


Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys 
    610                 615                 620


Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu Val 
625                 630                 635                 640


Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val Arg 
                645                 650                 655


Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg Gly 
            660                 665                 670


Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys 
        675                 680                 685


Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly 
    690                 695                 700


Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe Pro 
705                 710                 715                 720


Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg Arg 
                725                 730                 735


Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys 
            740                 745                 750


Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr Ala 
        755                 760                 765


Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser 
    770                 775                 780


Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn Ile 
785                 790                 795                 800


Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys Val 
                805                 810                 815


Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser Arg 
            820                 825                 830


Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro Tyr 
        835                 840                 845


Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met Pro 
    850                 855                 860


Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met 
865                 870                 875                 880


Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile Arg 
                885                 890                 895


Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser Glu 
            900                 905                 910


Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu 
        915                 920                 925


Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile 
    930                 935                 940


Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950


<210>  5222
<211>  7049
<212>  DNA
<213>  Homo sapiens

<400>  5222
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1980

catatcctgt gtttgaatca aacccggagt tcttgaaagg atcgtccgcg ggagtaataa   2040

aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc ctgggatggc   2100

tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc ctgggagtaa   2160

ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca atcctcaaac   2220

ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca agccacgagg   2280

gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac agaaagttga   2340

aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg tgaaggtgcc   2400

gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac ctgagggtgt   2460

gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac tcagaaacaa   2520

agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga ttaaggagag   2580

cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta atactactgc   2640

atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg ataatgaaag   2700

actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc tctttagtcg   2760

gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca ggaaaatcac   2820

aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct tcaaagcccc   2880

cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt ttatcaaatt   2940

cacggtcatt aggtaagtga gagtttcctg cttagtcaca ggagcgaatc tggagctcat   3000

gaggctgact cttctaaaat gcagccacag gtagtcatcg aatccggctt cctatgctgt   3060

gcaatcaaca aatcaaaata acttgtgtca tcattagaat gtcagatgtg cttctacgaa   3120

ctaagctgac tcttttaatt ctttggcaaa gggttggcaa actaggactg tttgccaaat   3180

tcaggctgcc tcctattttt agagtcttcc tgaaacacag ctacacccgt attatccatg   3240

gctgctttcc tgtcacagtg agtaagtagc tgggactgag aaggcatggc ctccaaagtc   3300

taaaatattt actctctagc actttgtaga aaaaccttag ctaggcacag tggctaacgc   3360

ctgtaatccc agcattttgg gaggccaagg caggcagatc acctgaggtc aggagttcca   3420

gaccagcctg gccaacatgg tgaaatccca tctctacaaa aataaaacag ttagctgggc   3480

atgatggcgg gtgcctgtaa tcccagctac tcgggaggct gaggcaggat agtcgcttga   3540

acccaggagg tggaggttgc aatgagccaa gatcatgcca ctgcactcca gcctggacga   3600

cagagtgaga ctccatcaca agaaaaaaag aactttgtca acctctgtct tagggcgcct   3660

tgtcacaggc ttcgggtcag acggattcaa ccttgcatca gccatttgtt agccaggtca   3720

ctctgttctt tgtctgtaaa tgagattgat cgttgttccc actgagagtg tcagctcctt   3780

cccgtagagc aggcatgatg attgtactca cctctgacac cattgtgagt gccacattcc   3840

ttcccacgtc cttgtcactg taagagatgc ccacctgagc accaacccca ggttatcttc   3900

ccctttgtct tccagccccc cagaaacagc tacgactcaa cctacccaat catttcatca   3960

tcagattgcc actgtctcta gttcaggtct cttgggactg gcactcagaa atctcataat   4020

aaatcctctt gaggcttctc atacactcgt cttcttccaa tcttctttcc ctcaaaatct   4080

catattttgg ttccacttca cccaccgtca ttctccatat cactcccagg agttaggcaa   4140

aaagcccctt ccgttcttcc gtatgttaaa cttagaatca ctctgttccc tgctctgcgt   4200

ttctattttt tgtttttcct ccatttacta gtagcttaac actttctaac agtgttctta   4260

ttattgatac gtatctatct cttccataag cttataaggt cacggataat acttctcatt   4320

gtagtacgta aatgacgtgg gctagatatg agttgaataa acagttatac ctgtaaattc   4380

ttacagagtg aaaataaatt gttatacttt acaatttgtt tctctcttta gaccatttcc   4440

aggacttgtg attaataacc gtgagtattt tgtgaagtgt tttgtttttg ttttttcctg   4500

gggtctgacg tgtgtgcgtg tgagtgtgta tacatgctta acgtatatca cgttacttca   4560

cctatgtcag taaccaggcc aaatacttgt tttagccctc agtaaaaaca ccaggcactt   4620

cctagttgta aaattattca agcttcttaa cttcctatcc tcgatgcact taatcataaa   4680

atggtaataa tagcaccgat tttgggggag tcgttccagt agatggaaag catctggaac   4740

aggtgtcagc aagctcctgc cgacgtgtat gcataaagtt ttattgaaac caccatcgtg   4800

tccatttgtt tatggcagaa ctgagagatg gcagcagcaa gtgtgtgcct gcaaaaccta   4860

aaatatttac taattggctc tgcaagaaaa gagtttgcat ccccctaacc tagaacagtg   4920

tctagcctct agtatgtgtt tagcctacag tatgtgctca gcgaatacaa tctatattta   4980

ttactgcttt tatgactgtt ataattactg tgcttggatt tcgttacaaa gtaagtcaca   5040

atgtgcctgc ttctgttagt atttcagcac agtgcctggc acacatgggg ctctcaaata   5100

ttgctgagcg agtgaacaaa tgtcctttca attccttaac gttgatgtca ttttcaatag   5160

tattttgagc caaacttaat tttgcgagtg tgttttgttt tcttaacttt attattaaaa   5220

atgtataaaa gtgaggccag gcgtggtggc tcacgcctgt aatcccagca gtttgggagg   5280

ctgaggcagg cggatcagtt gaggttggga gttggagacc agcccgtcca acatggtgaa   5340

agcctgtctc tactaaaaat acaaaaatca gctgggtgtg gtggcgcgtg cctgtaatcc   5400

cagctactca ggaggctgag gcaggagagt tgcttgaatc ctagaggtgg aggttgcagt   5460

gagctgagat cgtgccattg cactccagcc tgggcaacaa gagcaaaact ctgtcccaat   5520

aaataaataa ataaaatgtt ctcttttgtt cctgttcttg tgcggtagtg tggtatagag   5580

ttttatggta attactgtga attagtgatt ctgagggaca tatcagaact ctgaggtttg   5640

tttccttctc atcttgaggg aaacagcaaa tgtatgttaa aatgcttttc caagggaaca   5700

acacatcctt acattattta aaccaatctg cttcattttc agagctggtt gatcagagtg   5760

agtcagaagg ccccgtgata caagaatcag ctgaaccaag ccagttggaa gttccagcca   5820

cagaagaaat aaaagagact gatggaagct ctcagatcaa gcaagaacca gaccccacgt   5880

ggtagacctc ttccctccta ggcttaaagt atcagtggtt gagaagagct tttcggacct   5940

gttactaccc caagctgtgt aatatacttg tataacagaa ataccttcta tacaaacctt   6000

tttttctact tttagataga aatgtctact ttttcagcag ttctgtgaat taaagagcag   6060

agtgactgtg ggtctggaat ggctggtgta cttgggaatg tactatcagg attttacagc   6120

aatgctggga aatgacaggg aaaatgacag gaatgaatct caccagattt tttatgtact   6180

cagcagagcc ttgagttacg gtgtttattt tccaatcaag tgaagatatc tcctacttct   6240

cctactggaa catctcagct tctgcagtga agaaaaattc ctgtgatagt tcagttcttt   6300

agtttttcta tttgaaaaaa aaaaatcatt taaatgatcc tttgttcacg gctctcctta   6360

atgactgagt gaacagttcc tatctgtata tttgactaaa ccttttccta agctatctct   6420

catggttcct atgttttttt atcataatta aaagcaaaac catctggatc acctaacagt   6480

cagaggtcag tatctcagcg tgtgaattat agaggaaata cagagagaac ctcttccact   6540

tttacttttc gtccaaataa aatgcatggt gtaccagaag ttgaagatcg ggttgaggat   6600

tggggctagc tcgatgacac taaggcccca acatcgcggg acctgctgtg gcgcggattc   6660

ttaggaacgc tgttctagcc ggccccctct ccaggggtcg ccgtggccgg cattatttcc   6720

tagttcttct tgtaaccctg aggtgccagc gcggggagtg aggaggggtc agggggctaa   6780

ggatgcaacc tctgacgttc tgcgccttcc taggagagtc ttacatgtgt tgagatttca   6840

caagcaatgc gagttgtaaa ataccagctc tacaagaagc taggctctgt gacggcatag   6900

ttttcagtag ctttatcaca atattcacaa tggagaatta tatgacatgg tagcagaaat   6960

aggccctttt atgtgttgct tctattttac ctcaaattgt agatataggg taatcaataa   7020

aatccatcca tgcctttcac acactaagt                                     7049


<210>  5223
<211>  604
<212>  PRT
<213>  Homo sapiens

<400>  5223

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr 
                565                 570                 575


Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala Gly 
            580                 585                 590


Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600


<210>  5224
<211>  3999
<212>  DNA
<213>  Homo sapiens

<400>  5224
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agctcaagct cttggactca ccgaggcagt aaaagtacca tatcctgtgt   1920

ttgaatcaaa cccggagttc ttgtatgtgg aaggcttgcc agaggggatt cccttccgaa   1980

gccctacctg gtttggaatt ccacgacttg aaaggatcgt ccgcgggagt aataaaatca   2040

agttcgttgt taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta   2100

aaataaacac taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa   2160

aggttcctga aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag   2220

ctgttcgaac cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag   2280

agttttcctt tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc   2340

tcttcaatga gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg   2400

cgttatttga gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat   2460

tccgaagacc atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca   2520

aaattaagtt catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct   2580

cctctaagag ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag   2640

gtgttgaaga ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct   2700

cgaaagttga aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat   2760

ttggtgaagc tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta   2820

accctggctg tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct   2880

acctggaaat cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg   2940

tcattagacc atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag   3000

aaggccccgt gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag   3060

aaataaaaga gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga   3120

cctcttccct cctaggagcc ttgagttacg gtgtttattt tccaatcaag tgaagatatc   3180

tcctacttct cctactggaa catctcagct tctgcagtga agaaaaattc ctgtgatagt   3240

tcagttcttt agtttttcta tttgaaaaaa aaaaatcatt taaatgatcc tttgttcacg   3300

gctctcctta atgactgagt gaacagttcc tatctgtata tttgactaaa ccttttccta   3360

agctatctct catggttcct atgttttttt atcataatta aaagcaaaac catctggatc   3420

acctaacagt cagaggtcag tatctcagcg tgtgaattat agaggaaata cagagagaac   3480

ctcttccact tttacttttc gtccaaataa aatgcatggt gtaccagaag ttgaagatcg   3540

ggttgaggat tggggctagc tcgatgacac taaggcccca acatcgcggg acctgctgtg   3600

gcgcggattc ttaggaacgc tgttctagcc ggccccctct ccaggggtcg ccgtggccgg   3660

cattatttcc tagttcttct tgtaaccctg aggtgccagc gcggggagtg aggaggggtc   3720

agggggctaa ggatgcaacc tctgacgttc tgcgccttcc taggagagtc ttacatgtgt   3780

tgagatttca caagcaatgc gagttgtaaa ataccagctc tacaagaagc taggctctgt   3840

gacggcatag ttttcagtag ctttatcaca atattcacaa tggagaatta tatgacatgg   3900

tagcagaaat aggccctttt atgtgttgct tctattttac ctcaaattgt agatataggg   3960

taatcaataa aatccatcca tgcctttcac acactaagt                          3999


<210>  5225
<211>  953
<212>  PRT
<213>  Homo sapiens

<400>  5225

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly Leu 
    530                 535                 540


Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu 
545                 550                 555                 560


Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro 
                565                 570                 575


Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn 
            580                 585                 590


Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu 
        595                 600                 605


Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro 
    610                 615                 620


Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu 
625                 630                 635                 640


Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val 
                645                 650                 655


Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg 
            660                 665                 670


Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu 
        675                 680                 685


Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu 
    690                 695                 700


Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe 
705                 710                 715                 720


Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg 
                725                 730                 735


Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn 
            740                 745                 750


Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr 
        755                 760                 765


Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn 
    770                 775                 780


Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn 
785                 790                 795                 800


Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys 
                805                 810                 815


Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser 
            820                 825                 830


Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro 
        835                 840                 845


Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met 
    850                 855                 860


Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser 
865                 870                 875                 880


Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile 
                885                 890                 895


Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser 
            900                 905                 910


Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu 
        915                 920                 925


Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln 
    930                 935                 940


Ile Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950


<210>  5226
<211>  4996
<212>  DNA
<213>  Homo sapiens

<400>  5226
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1980

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   2040

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2100

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2160

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2220

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2280

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2340

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2400

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2460

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2520

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2580

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2640

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2700

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2760

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2820

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2880

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2940

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   3000

tcaaattcac ggtcattaga ccatttccag gacttgtgat taataaccag ctggttgatc   3060

agagtgagtc agaaggcccc gtgatacaag aatcagctga accaagccag ttggaagttc   3120

cagccacaga aggtaaaagg acctcttccc tcctagggta aatcagcttc tgtgtcaggg   3180

atgctgtgtg gtgtccatct gaaccccctg catacgcgta gctaatgtga tctccccact   3240

ttcacataag atggtggccc tgccttcagg gaatgtggga gccaggtggg agccttcccg   3300

gatatttaag ctagaagatt ctacagggag attctccttg gatcaatata tgtctctcag   3360

tcaaagatgt aaaagcactt ttgccttaaa aagaatgttc tgtttctaaa tagagtcaac   3420

gttgtcctcc tcattggaat tcactatgag tcagaatcat tagactgact tttttttttc   3480

catagtaata gtattttgca gagtctcaca gagctgcaga tcttttgttc atcttgcaga   3540

gttaacaagt ctgatcctgt tagtccagat ttcttaaatt tggccaagtt ataataggag   3600

cagtagcttg agacccgaag tcaggaaact ttgacaatgg attttttttt ttaatccaga   3660

gacttgtact ggaatttgcc ttaccctgtc agctcatgga cttaaggttt catcccgctt   3720

tatgagtgct tctgaatcca agtcattgtt acctgaattt gcaaattaag ttgtgatatt   3780

cgtgactgtt aaattcctgt aattagatta acctctttgc ttgcttgttt gttttctctc   3840

ctattttagc ttaaagtatc agtggttgag aagagctttt cggacctgtt actaccccaa   3900

gctgtgtaat atacttgtat aacagaaata ccttctatac aaaccttttt ttctactttt   3960

agatagaaat gtctactttt tcagcagttc tgtgaattaa agagcagagt gactgtgggt   4020

ctggaatggc tggtgtactt gggaatgtac tatcaggatt ttacagcaat gctgggaaat   4080

gacagggaaa atgacaggaa tgaatctcac cagatttttt atgtactcag cagagccttg   4140

agttacggtg tttattttcc aatcaagtga agatatctcc tacttctcct actggaacat   4200

ctcagcttct gcagtgaaga aaaattcctg tgatagttca gttctttagt ttttctattt   4260

gaaaaaaaaa aatcatttaa atgatccttt gttcacggct ctccttaatg actgagtgaa   4320

cagttcctat ctgtatattt gactaaacct tttcctaagc tatctctcat ggttcctatg   4380

tttttttatc ataattaaaa gcaaaaccat ctggatcacc taacagtcag aggtcagtat   4440

ctcagcgtgt gaattataga ggaaatacag agagaacctc ttccactttt acttttcgtc   4500

caaataaaat gcatggtgta ccagaagttg aagatcgggt tgaggattgg ggctagctcg   4560

atgacactaa ggccccaaca tcgcgggacc tgctgtggcg cggattctta ggaacgctgt   4620

tctagccggc cccctctcca ggggtcgccg tggccggcat tatttcctag ttcttcttgt   4680

aaccctgagg tgccagcgcg gggagtgagg aggggtcagg gggctaagga tgcaacctct   4740

gacgttctgc gccttcctag gagagtctta catgtgttga gatttcacaa gcaatgcgag   4800

ttgtaaaata ccagctctac aagaagctag gctctgtgac ggcatagttt tcagtagctt   4860

tatcacaata ttcacaatgg agaattatat gacatggtag cagaaatagg cccttttatg   4920

tgttgcttct attttacctc aaattgtaga tatagggtaa tcaataaaat ccatccatgc   4980

ctttcacaca ctaagt                                                   4996


<210>  5227
<211>  967
<212>  PRT
<213>  Homo sapiens

<400>  5227

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr 
                565                 570                 575


Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro 
            580                 585                 590


Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu 
        595                 600                 605


Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys 
    610                 615                 620


Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile 
625                 630                 635                 640


Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser 
                645                 650                 655


Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn 
            660                 665                 670


Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly 
        675                 680                 685


Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala 
    690                 695                 700


Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe 
705                 710                 715                 720


Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val 
                725                 730                 735


Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly 
            740                 745                 750


Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro 
        755                 760                 765


Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile 
    770                 775                 780


Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser 
785                 790                 795                 800


Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr 
                805                 810                 815


Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp 
            820                 825                 830


Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg 
        835                 840                 845


Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly 
    850                 855                 860


Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro 
865                 870                 875                 880


Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala 
                885                 890                 895


Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala 
            900                 905                 910


Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile 
        915                 920                 925


Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln 
    930                 935                 940


Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Gly Lys 
945                 950                 955                 960


Arg Thr Ser Ser Leu Leu Gly 
                965


<210>  5228
<211>  7920
<212>  DNA
<213>  Homo sapiens

<400>  5228
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgcttaga tttgttgaca gcggtttcct ggagtgctgt   1980

cttgagaacg attctgagga ggctcagcaa gaaagagtgt ttcagttgat tgggtgtgtc   2040

tgtcatggag aaggaactca agctcttgga ctcaccgagg cagtaaaagt accatatcct   2100

gtgtttgaat caaacccgga gttcttgtat gtggaaggct tgccagaggg gattcccttc   2160

cgaagcccta cctggtttgg aattccacga cttgaaagga tcgtccgcgg gagtaataaa   2220

atcaagttcg ttgttaaaaa acctgaacta gttatttcct acttgcctcc tgggatggct   2280

agtaaaataa acactaaagc tttgcagtcc cccaaaagac cacgaagtcc tgggagtaat   2340

tcaaaggttc ctgaaattga ggtcaccgtg gaaggcccta ataacaacaa tcctcaaacc   2400

tcagctgttc gaaccccgac ccagactaac ggttctaacg ttcccttcaa gccacgaggg   2460

agagagtttt cctttgaggc ctggaatgcc aaaatcacgg acctaaaaca gaaagttgaa   2520

aatctcttca atgagaaatg tggggaagct cttggcctta aacaagctgt gaaggtgccg   2580

ttcgcgttat ttgagtcttt cccggaagac ttttatgtgg aaggcttacc tgagggtgtg   2640

ccattccgaa gaccatcgac ttttggcatt ccgaggctgg agaagatact cagaaacaaa   2700

gccaaaatta agttcatcat taaaaagccc gaaatgtttg agacggcgat taaggagagc   2760

acctcctcta agagccctcc cagaaaaata aattcatcac ccaatgttaa tactactgca   2820

tcaggtgttg aagaccttaa catcattcag gtgacaattc cagatgatga taatgaaaga   2880

ctctcgaaag ttgaaaaagc tagacagcta agagaacaag tgaatgacct ctttagtcgg   2940

aaatttggtg aagctattgg tatgggtttt cctgtgaaag ttccctacag gaaaatcaca   3000

attaaccctg gctgtgtggt ggttgatggc atgcccccgg gggtgtcctt caaagccccc   3060

agctacctgg aaatcagctc catgagaagg atcttagact ctgccgagtt tatcaaattc   3120

acggtcatta ggtaagtgag agtttcctgc ttagtcacag gagcgaatct ggagctcatg   3180

aggctgactc ttctaaaatg cagccacagg tagtcatcga atccggcttc ctatgctgtg   3240

caatcaacaa atcaaaataa cttgtgtcat cattagaatg tcagatgtgc ttctacgaac   3300

taagctgact cttttaattc tttggcaaag ggttggcaaa ctaggactgt ttgccaaatt   3360

caggctgcct cctattttta gagtcttcct gaaacacagc tacacccgta ttatccatgg   3420

ctgctttcct gtcacagtga gtaagtagct gggactgaga aggcatggcc tccaaagtct   3480

aaaatattta ctctctagca ctttgtagaa aaaccttagc taggcacagt ggctaacgcc   3540

tgtaatccca gcattttggg aggccaaggc aggcagatca cctgaggtca ggagttccag   3600

accagcctgg ccaacatggt gaaatcccat ctctacaaaa ataaaacagt tagctgggca   3660

tgatggcggg tgcctgtaat cccagctact cgggaggctg aggcaggata gtcgcttgaa   3720

cccaggaggt ggaggttgca atgagccaag atcatgccac tgcactccag cctggacgac   3780

agagtgagac tccatcacaa gaaaaaaaga actttgtcaa cctctgtctt agggcgcctt   3840

gtcacaggct tcgggtcaga cggattcaac cttgcatcag ccatttgtta gccaggtcac   3900

tctgttcttt gtctgtaaat gagattgatc gttgttccca ctgagagtgt cagctccttc   3960

ccgtagagca ggcatgatga ttgtactcac ctctgacacc attgtgagtg ccacattcct   4020

tcccacgtcc ttgtcactgt aagagatgcc cacctgagca ccaaccccag gttatcttcc   4080

cctttgtctt ccagcccccc agaaacagct acgactcaac ctacccaatc atttcatcat   4140

cagattgcca ctgtctctag ttcaggtctc ttgggactgg cactcagaaa tctcataata   4200

aatcctcttg aggcttctca tacactcgtc ttcttccaat cttctttccc tcaaaatctc   4260

atattttggt tccacttcac ccaccgtcat tctccatatc actcccagga gttaggcaaa   4320

aagccccttc cgttcttccg tatgttaaac ttagaatcac tctgttccct gctctgcgtt   4380

tctatttttt gtttttcctc catttactag tagcttaaca ctttctaaca gtgttcttat   4440

tattgatacg tatctatctc ttccataagc ttataaggtc acggataata cttctcattg   4500

tagtacgtaa atgacgtggg ctagatatga gttgaataaa cagttatacc tgtaaattct   4560

tacagagtga aaataaattg ttatacttta caatttgttt ctctctttag accatttcca   4620

ggacttgtga ttaataaccg tgagtatttt gtgaagtgtt ttgtttttgt tttttcctgg   4680

ggtctgacgt gtgtgcgtgt gagtgtgtat acatgcttaa cgtatatcac gttacttcac   4740

ctatgtcagt aaccaggcca aatacttgtt ttagccctca gtaaaaacac caggcacttc   4800

ctagttgtaa aattattcaa gcttcttaac ttcctatcct cgatgcactt aatcataaaa   4860

tggtaataat agcaccgatt ttgggggagt cgttccagta gatggaaagc atctggaaca   4920

ggtgtcagca agctcctgcc gacgtgtatg cataaagttt tattgaaacc accatcgtgt   4980

ccatttgttt atggcagaac tgagagatgg cagcagcaag tgtgtgcctg caaaacctaa   5040

aatatttact aattggctct gcaagaaaag agtttgcatc cccctaacct agaacagtgt   5100

ctagcctcta gtatgtgttt agcctacagt atgtgctcag cgaatacaat ctatatttat   5160

tactgctttt atgactgtta taattactgt gcttggattt cgttacaaag taagtcacaa   5220

tgtgcctgct tctgttagta tttcagcaca gtgcctggca cacatggggc tctcaaatat   5280

tgctgagcga gtgaacaaat gtcctttcaa ttccttaacg ttgatgtcat tttcaatagt   5340

attttgagcc aaacttaatt ttgcgagtgt gttttgtttt cttaacttta ttattaaaaa   5400

tgtataaaag tgaggccagg cgtggtggct cacgcctgta atcccagcag tttgggaggc   5460

tgaggcaggc ggatcagttg aggttgggag ttggagacca gcccgtccaa catggtgaaa   5520

gcctgtctct actaaaaata caaaaatcag ctgggtgtgg tggcgcgtgc ctgtaatccc   5580

agctactcag gaggctgagg caggagagtt gcttgaatcc tagaggtgga ggttgcagtg   5640

agctgagatc gtgccattgc actccagcct gggcaacaag agcaaaactc tgtcccaata   5700

aataaataaa taaaatgttc tcttttgttc ctgttcttgt gcggtagtgt ggtatagagt   5760

tttatggtaa ttactgtgaa ttagtgattc tgagggacat atcagaactc tgaggtttgt   5820

ttccttctca tcttgaggga aacagcaaat gtatgttaaa atgcttttcc aagggaacaa   5880

cacatcctta cattatttaa accaatctgc ttcattttca gagctggttg atcagagtga   5940

gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag ttccagccac   6000

agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag accccacgtg   6060

gtagacctct tccctcctag ggtaaatcag cttctgtgtc agggatgctg tgtggtgtcc   6120

atctgaaccc cctgcatacg cgtagctaat gtgatctccc cactttcaca taagatggtg   6180

gccctgcctt cagggaatgt gggagccagg tgggagcctt cccggatatt taagctagaa   6240

gattctacag ggagattctc cttggatcaa tatatgtctc tcagtcaaag atgtaaaagc   6300

acttttgcct taaaaagaat gttctgtttc taaatagagt caacgttgtc ctcctcattg   6360

gaattcacta tgagtcagaa tcattagact gacttttttt tttccatagt aatagtattt   6420

tgcagagtct cacagagctg cagatctttt gttcatcttg cagagttaac aagtctgatc   6480

ctgttagtcc agatttctta aatttggcca agttataata ggagcagtag cttgagaccc   6540

gaagtcagga aactttgaca atggattttt ttttttaatc cagagacttg tactggaatt   6600

tgccttaccc tgtcagctca tggacttaag gtttcatccc gctttatgag tgcttctgaa   6660

tccaagtcat tgttacctga atttgcaaat taagttgtga tattcgtgac tgttaaattc   6720

ctgtaattag attaacctct ttgcttgctt gtttgttttc tctcctattt tagcttaaag   6780

tatcagtggt tgagaagagc ttttcggacc tgttactacc ccaagctgtg taatatactt   6840

gtataacaga aataccttct atacaaacct ttttttctac ttttagatag aaatgtctac   6900

tttttcagca gttctgtgaa ttaaagagca gagtgactgt gggtctggaa tggctggtgt   6960

acttgggaat gtactatcag gattttacag caatgctggg aaatgacagg gaaaatgaca   7020

ggaatgaatc tcaccagatt ttttatgtac tcagcagagc cttgagttac ggtgtttatt   7080

ttccaatcaa gtgaagatat ctcctacttc tcctactgga acatctcagc ttctgcagtg   7140

aagaaaaatt cctgtgatag ttcagttctt tagtttttct atttgaaaaa aaaaaatcat   7200

ttaaatgatc ctttgttcac ggctctcctt aatgactgag tgaacagttc ctatctgtat   7260

atttgactaa accttttcct aagctatctc tcatggttcc tatgtttttt tatcataatt   7320

aaaagcaaaa ccatctggat cacctaacag tcagaggtca gtatctcagc gtgtgaatta   7380

tagaggaaat acagagagaa cctcttccac ttttactttt cgtccaaata aaatgcatgg   7440

tgtaccagaa gttgaagatc gggttgagga ttggggctag ctcgatgaca ctaaggcccc   7500

aacatcgcgg gacctgctgt ggcgcggatt cttaggaacg ctgttctagc cggccccctc   7560

tccaggggtc gccgtggccg gcattatttc ctagttcttc ttgtaaccct gaggtgccag   7620

cgcggggagt gaggaggggt cagggggcta aggatgcaac ctctgacgtt ctgcgccttc   7680

ctaggagagt cttacatgtg ttgagatttc acaagcaatg cgagttgtaa aataccagct   7740

ctacaagaag ctaggctctg tgacggcata gttttcagta gctttatcac aatattcaca   7800

atggagaatt atatgacatg gtagcagaaa taggcccttt tatgtgttgc ttctatttta   7860

cctcaaattg tagatatagg gtaatcaata aaatccatcc atgcctttca cacactaagt   7920


<210>  5229
<211>  563
<212>  PRT
<213>  Homo sapiens

<400>  5229

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala 



<210>  5230
<211>  3806
<212>  DNA
<213>  Homo sapiens

<400>  5230
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgta tgtggaaggc ttgccagagg   2040

ggattccctt ccgaagccct acctggtttg gaattccacg acttgaaagg atcgtccgcg   2100

ggagtaataa aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc   2160

ctgggatggc tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc   2220

ctgggagtaa ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca   2280

atcctcaaac ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca   2340

agccacgagg gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac   2400

agaaagttga aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg   2460

tgaaggtgcc gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac   2520

ctgagggtgt gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac   2580

tcagaaacaa agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga   2640

ttaaggagag cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta   2700

atactactgc atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg   2760

ataatgaaag actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc   2820

tctttagtcg gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca   2880

ggaaaatcac aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct   2940

tcaaagcccc cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt   3000

ttatcaaatt cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg   3060

atcagagtga gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag   3120

ttccagccac agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag   3180

accccacgtg gtagacctct tccctcctag gcaaaaccat ctggatcacc taacagtcag   3240

aggtcagtat ctcagcgtgt gaattataga ggaaatacag agagaacctc ttccactttt   3300

acttttcgtc caaataaaat gcatggtgta ccagaagttg aagatcgggt tgaggattgg   3360

ggctagctcg atgacactaa ggccccaaca tcgcgggacc tgctgtggcg cggattctta   3420

ggaacgctgt tctagccggc cccctctcca ggggtcgccg tggccggcat tatttcctag   3480

ttcttcttgt aaccctgagg tgccagcgcg gggagtgagg aggggtcagg gggctaagga   3540

tgcaacctct gacgttctgc gccttcctag gagagtctta catgtgttga gatttcacaa   3600

gcaatgcgag ttgtaaaata ccagctctac aagaagctag gctctgtgac ggcatagttt   3660

tcagtagctt tatcacaata ttcacaatgg agaattatat gacatggtag cagaaatagg   3720

cccttttatg tgttgcttct attttacctc aaattgtaga tatagggtaa tcaataaaat   3780

ccatccatgc ctttcacaca ctaagt                                        3806


<210>  5231
<211>  978
<212>  PRT
<213>  Homo sapiens

<400>  5231

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu 
            580                 585                 590


Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg 
        595                 600                 605


Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys 
    610                 615                 620


Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys 
625                 630                 635                 640


Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly 
                645                 650                 655


Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn 
            660                 665                 670


Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn 
        675                 680                 685


Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu 
    690                 695                 700


Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu 
705                 710                 715                 720


Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys 
                725                 730                 735


Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu 
            740                 745                 750


Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile 
        755                 760                 765


Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile 
    770                 775                 780


Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser 
785                 790                 795                 800


Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr 
                805                 810                 815


Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro 
            820                 825                 830


Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu 
        835                 840                 845


Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile 
    850                 855                 860


Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn 
865                 870                 875                 880


Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys 
                885                 890                 895


Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser 
            900                 905                 910


Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val 
        915                 920                 925


Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile 
    930                 935                 940


Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu 
945                 950                 955                 960


Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro 
                965                 970                 975


Thr Trp 



<210>  5232
<211>  5043
<212>  DNA
<213>  Homo sapiens

<400>  5232
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1980

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   2040

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2100

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2160

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2220

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2280

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2340

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2400

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2460

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2520

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2580

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2640

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2700

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2760

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2820

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2880

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2940

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   3000

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3060

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3120

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3180

gtggtagacc tcttccctcc tagggtaaat cagcttctgt gtcagggatg ctgtgtggtg   3240

tccatctgaa ccccctgcat acgcgtagct aatgtgatct ccccactttc acataagatg   3300

gtggccctgc cttcagggaa tgtgggagcc aggtgggagc cttcccggat atttaagcta   3360

gaagattcta cagggagatt ctccttggat caatatatgt ctctcagtca aagatgtaaa   3420

agcacttttg ccttaaaaag aatgttctgt ttctaaatag agtcaacgtt gtcctcctca   3480

ttggaattca ctatgagtca gaatcattag actgactttt ttttttccat agtaatagta   3540

ttttgcagag tctcacagag ctgcagatct tttgttcatc ttgcagagtt aacaagtctg   3600

atcctgttag tccagatttc ttaaatttgg ccaagttata ataggagcag tagcttgaga   3660

cccgaagtca ggaaactttg acaatggatt ttttttttta atccagagac ttgtactgga   3720

atttgcctta ccctgtcagc tcatggactt aaggtttcat cccgctttat gagtgcttct   3780

gaatccaagt cattgttacc tgaatttgca aattaagttg tgatattcgt gactgttaaa   3840

ttcctgtaat tagattaacc tctttgcttg cttgtttgtt ttctctccta ttttagctta   3900

aagtatcagt ggttgagaag agcttttcgg acctgttact accccaagct gtgtaatata   3960

cttgtataac agaaatacct tctatacaaa cctttttttc tacttttaga tagaaatgtc   4020

tactttttca gcagttctgt gaattaaaga gcagagtgac tgtgggtctg gaatggctgg   4080

tgtacttggg aatgtactat caggatttta cagcaatgct gggaaatgac agggaaaatg   4140

acaggaatga atctcaccag attttttatg tactcagcag agccttgagt tacggtgttt   4200

attttccaat caagtgaaga tatctcctac ttctcctact ggaacatctc agcttctgca   4260

gtgaagaaaa attcctgtga tagttcagtt ctttagtttt tctatttgaa aaaaaaaaat   4320

catttaaatg atcctttgtt cacggctctc cttaatgact gagtgaacag ttcctatctg   4380

tatatttgac taaacctttt cctaagctat ctctcatggt tcctatgttt ttttatcata   4440

attaaaagca aaaccatctg gatcacctaa cagtcagagg tcagtatctc agcgtgtgaa   4500

ttatagagga aatacagaga gaacctcttc cacttttact tttcgtccaa ataaaatgca   4560

tggtgtacca gaagttgaag atcgggttga ggattggggc tagctcgatg acactaaggc   4620

cccaacatcg cgggacctgc tgtggcgcgg attcttagga acgctgttct agccggcccc   4680

ctctccaggg gtcgccgtgg ccggcattat ttcctagttc ttcttgtaac cctgaggtgc   4740

cagcgcgggg agtgaggagg ggtcaggggg ctaaggatgc aacctctgac gttctgcgcc   4800

ttcctaggag agtcttacat gtgttgagat ttcacaagca atgcgagttg taaaatacca   4860

gctctacaag aagctaggct ctgtgacggc atagttttca gtagctttat cacaatattc   4920

acaatggaga attatatgac atggtagcag aaataggccc ttttatgtgt tgcttctatt   4980

ttacctcaaa ttgtagatat agggtaatca ataaaatcca tccatgcctt tcacacacta   5040

agt                                                                 5043


<210>  5233
<211>  625
<212>  PRT
<213>  Homo sapiens

<400>  5233

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val 
545                 550                 555                 560


Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu 
                565                 570                 575


Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala 
            580                 585                 590


Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys 
        595                 600                 605


Gly Ser Ser Ala Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu 
    610                 615                 620


Asn 
625


<210>  5234
<211>  3799
<212>  DNA
<213>  Homo sapiens

<400>  5234
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1980

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   2040

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2100

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2160

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2220

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2280

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2340

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2400

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2460

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2520

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2580

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2640

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2700

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2760

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2820

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2880

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2940

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   3000

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3060

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3120

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3180

gtggtagacc tcttccctcc taggcaaaac catctggatc acctaacagt cagaggtcag   3240

tatctcagcg tgtgaattat agaggaaata cagagagaac ctcttccact tttacttttc   3300

gtccaaataa aatgcatggt gtaccagaag ttgaagatcg ggttgaggat tggggctagc   3360

tcgatgacac taaggcccca acatcgcggg acctgctgtg gcgcggattc ttaggaacgc   3420

tgttctagcc ggccccctct ccaggggtcg ccgtggccgg cattatttcc tagttcttct   3480

tgtaaccctg aggtgccagc gcggggagtg aggaggggtc agggggctaa ggatgcaacc   3540

tctgacgttc tgcgccttcc taggagagtc ttacatgtgt tgagatttca caagcaatgc   3600

gagttgtaaa ataccagctc tacaagaagc taggctctgt gacggcatag ttttcagtag   3660

ctttatcaca atattcacaa tggagaatta tatgacatgg tagcagaaat aggccctttt   3720

atgtgttgct tctattttac ctcaaattgt agatataggg taatcaataa aatccatcca   3780

tgcctttcac acactaagt                                                3799


<210>  5235
<211>  625
<212>  PRT
<213>  Homo sapiens

<400>  5235

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val 
545                 550                 555                 560


Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu 
                565                 570                 575


Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala 
            580                 585                 590


Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys 
        595                 600                 605


Gly Ser Ser Ala Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu 
    610                 615                 620


Asn 
625


<210>  5236
<211>  5050
<212>  DNA
<213>  Homo sapiens

<400>  5236
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgta tgtggaaggc ttgccagagg   2040

ggattccctt ccgaagccct acctggtttg gaattccacg acttgaaagg atcgtccgcg   2100

ggagtaataa aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc   2160

ctgggatggc tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc   2220

ctgggagtaa ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca   2280

atcctcaaac ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca   2340

agccacgagg gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac   2400

agaaagttga aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg   2460

tgaaggtgcc gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac   2520

ctgagggtgt gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac   2580

tcagaaacaa agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga   2640

ttaaggagag cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta   2700

atactactgc atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg   2760

ataatgaaag actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc   2820

tctttagtcg gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca   2880

ggaaaatcac aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct   2940

tcaaagcccc cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt   3000

ttatcaaatt cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg   3060

atcagagtga gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag   3120

ttccagccac agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag   3180

accccacgtg gtagacctct tccctcctag ggtaaatcag cttctgtgtc agggatgctg   3240

tgtggtgtcc atctgaaccc cctgcatacg cgtagctaat gtgatctccc cactttcaca   3300

taagatggtg gccctgcctt cagggaatgt gggagccagg tgggagcctt cccggatatt   3360

taagctagaa gattctacag ggagattctc cttggatcaa tatatgtctc tcagtcaaag   3420

atgtaaaagc acttttgcct taaaaagaat gttctgtttc taaatagagt caacgttgtc   3480

ctcctcattg gaattcacta tgagtcagaa tcattagact gacttttttt tttccatagt   3540

aatagtattt tgcagagtct cacagagctg cagatctttt gttcatcttg cagagttaac   3600

aagtctgatc ctgttagtcc agatttctta aatttggcca agttataata ggagcagtag   3660

cttgagaccc gaagtcagga aactttgaca atggattttt ttttttaatc cagagacttg   3720

tactggaatt tgccttaccc tgtcagctca tggacttaag gtttcatccc gctttatgag   3780

tgcttctgaa tccaagtcat tgttacctga atttgcaaat taagttgtga tattcgtgac   3840

tgttaaattc ctgtaattag attaacctct ttgcttgctt gtttgttttc tctcctattt   3900

tagcttaaag tatcagtggt tgagaagagc ttttcggacc tgttactacc ccaagctgtg   3960

taatatactt gtataacaga aataccttct atacaaacct ttttttctac ttttagatag   4020

aaatgtctac tttttcagca gttctgtgaa ttaaagagca gagtgactgt gggtctggaa   4080

tggctggtgt acttgggaat gtactatcag gattttacag caatgctggg aaatgacagg   4140

gaaaatgaca ggaatgaatc tcaccagatt ttttatgtac tcagcagagc cttgagttac   4200

ggtgtttatt ttccaatcaa gtgaagatat ctcctacttc tcctactgga acatctcagc   4260

ttctgcagtg aagaaaaatt cctgtgatag ttcagttctt tagtttttct atttgaaaaa   4320

aaaaaatcat ttaaatgatc ctttgttcac ggctctcctt aatgactgag tgaacagttc   4380

ctatctgtat atttgactaa accttttcct aagctatctc tcatggttcc tatgtttttt   4440

tatcataatt aaaagcaaaa ccatctggat cacctaacag tcagaggtca gtatctcagc   4500

gtgtgaatta tagaggaaat acagagagaa cctcttccac ttttactttt cgtccaaata   4560

aaatgcatgg tgtaccagaa gttgaagatc gggttgagga ttggggctag ctcgatgaca   4620

ctaaggcccc aacatcgcgg gacctgctgt ggcgcggatt cttaggaacg ctgttctagc   4680

cggccccctc tccaggggtc gccgtggccg gcattatttc ctagttcttc ttgtaaccct   4740

gaggtgccag cgcggggagt gaggaggggt cagggggcta aggatgcaac ctctgacgtt   4800

ctgcgccttc ctaggagagt cttacatgtg ttgagatttc acaagcaatg cgagttgtaa   4860

aataccagct ctacaagaag ctaggctctg tgacggcata gttttcagta gctttatcac   4920

aatattcaca atggagaatt atatgacatg gtagcagaaa taggcccttt tatgtgttgc   4980

ttctatttta cctcaaattg tagatatagg gtaatcaata aaatccatcc atgcctttca   5040

cacactaagt                                                          5050


<210>  5237
<211>  978
<212>  PRT
<213>  Homo sapiens

<400>  5237

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu 
            580                 585                 590


Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg 
        595                 600                 605


Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys 
    610                 615                 620


Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys 
625                 630                 635                 640


Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly 
                645                 650                 655


Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn 
            660                 665                 670


Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn 
        675                 680                 685


Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu 
    690                 695                 700


Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu 
705                 710                 715                 720


Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys 
                725                 730                 735


Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu 
            740                 745                 750


Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile 
        755                 760                 765


Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile 
    770                 775                 780


Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser 
785                 790                 795                 800


Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr 
                805                 810                 815


Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro 
            820                 825                 830


Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu 
        835                 840                 845


Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile 
    850                 855                 860


Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn 
865                 870                 875                 880


Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys 
                885                 890                 895


Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser 
            900                 905                 910


Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val 
        915                 920                 925


Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile 
    930                 935                 940


Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu 
945                 950                 955                 960


Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro 
                965                 970                 975


Thr Trp 



<210>  5238
<211>  4291
<212>  DNA
<213>  Homo sapiens

<400>  5238
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2040

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2100

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2160

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2220

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2280

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2340

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2400

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2460

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2520

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2580

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2640

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2700

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2760

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2820

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2880

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   2940

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3000

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3060

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3120

gtggtagacc tcttccctcc taggcttaaa gtatcagtgg ttgagaagag cttttcggac   3180

ctgttactac cccaagctgt gtaatatact tgtataacag aaataccttc tatacaaacc   3240

tttttttcta cttttagata gaaatgtcta ctttttcagc agttctgtga attaaagagc   3300

agagtgactg tgggtctgga atggctggtg tacttgggaa tgtactatca ggattttaca   3360

gcaatgctgg gaaatgacag ggaaaatgac aggaatgaat ctcaccagat tttttatgta   3420

ctcagcagag ccttgagtta cggtgtttat tttccaatca agtgaagata tctcctactt   3480

ctcctactgg aacatctcag cttctgcagt gaagaaaaat tcctgtgata gttcagttct   3540

ttagtttttc tatttgaaaa aaaaaaatca tttaaatgat cctttgttca cggctctcct   3600

taatgactga gtgaacagtt cctatctgta tatttgacta aaccttttcc taagctatct   3660

ctcatggttc ctatgttttt ttatcataat taaaagcaaa accatctgga tcacctaaca   3720

gtcagaggtc agtatctcag cgtgtgaatt atagaggaaa tacagagaga acctcttcca   3780

cttttacttt tcgtccaaat aaaatgcatg gtgtaccaga agttgaagat cgggttgagg   3840

attggggcta gctcgatgac actaaggccc caacatcgcg ggacctgctg tggcgcggat   3900

tcttaggaac gctgttctag ccggccccct ctccaggggt cgccgtggcc ggcattattt   3960

cctagttctt cttgtaaccc tgaggtgcca gcgcggggag tgaggagggg tcagggggct   4020

aaggatgcaa cctctgacgt tctgcgcctt cctaggagag tcttacatgt gttgagattt   4080

cacaagcaat gcgagttgta aaataccagc tctacaagaa gctaggctct gtgacggcat   4140

agttttcagt agctttatca caatattcac aatggagaat tatatgacat ggtagcagaa   4200

ataggccctt ttatgtgttg cttctatttt acctcaaatt gtagatatag ggtaatcaat   4260

aaaatccatc catgcctttc acacactaag t                                  4291


<210>  5239
<211>  605
<212>  PRT
<213>  Homo sapiens

<400>  5239

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala 
            580                 585                 590


Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600                 605


<210>  5240
<211>  7676
<212>  DNA
<213>  Homo sapiens

<400>  5240
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agctcaagct cttggactca ccgaggcagt aaaagtacca tatcctgtgt   1860

ttgaatcaaa cccggagttc ttgtatgtgg aaggcttgcc agaggggatt cccttccgaa   1920

gccctacctg gtttggaatt ccacgacttg aaaggatcgt ccgcgggagt aataaaatca   1980

agttcgttgt taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta   2040

aaataaacac taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa   2100

aggttcctga aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag   2160

ctgttcgaac cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag   2220

agttttcctt tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc   2280

tcttcaatga gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg   2340

cgttatttga gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat   2400

tccgaagacc atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca   2460

aaattaagtt catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct   2520

cctctaagag ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag   2580

gtgttgaaga ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct   2640

cgaaagttga aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat   2700

ttggtgaagc tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta   2760

accctggctg tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct   2820

acctggaaat cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg   2880

tcattaggta agtgagagtt tcctgcttag tcacaggagc gaatctggag ctcatgaggc   2940

tgactcttct aaaatgcagc cacaggtagt catcgaatcc ggcttcctat gctgtgcaat   3000

caacaaatca aaataacttg tgtcatcatt agaatgtcag atgtgcttct acgaactaag   3060

ctgactcttt taattctttg gcaaagggtt ggcaaactag gactgtttgc caaattcagg   3120

ctgcctccta tttttagagt cttcctgaaa cacagctaca cccgtattat ccatggctgc   3180

tttcctgtca cagtgagtaa gtagctggga ctgagaaggc atggcctcca aagtctaaaa   3240

tatttactct ctagcacttt gtagaaaaac cttagctagg cacagtggct aacgcctgta   3300

atcccagcat tttgggaggc caaggcaggc agatcacctg aggtcaggag ttccagacca   3360

gcctggccaa catggtgaaa tcccatctct acaaaaataa aacagttagc tgggcatgat   3420

ggcgggtgcc tgtaatccca gctactcggg aggctgaggc aggatagtcg cttgaaccca   3480

ggaggtggag gttgcaatga gccaagatca tgccactgca ctccagcctg gacgacagag   3540

tgagactcca tcacaagaaa aaaagaactt tgtcaacctc tgtcttaggg cgccttgtca   3600

caggcttcgg gtcagacgga ttcaaccttg catcagccat ttgttagcca ggtcactctg   3660

ttctttgtct gtaaatgaga ttgatcgttg ttcccactga gagtgtcagc tccttcccgt   3720

agagcaggca tgatgattgt actcacctct gacaccattg tgagtgccac attccttccc   3780

acgtccttgt cactgtaaga gatgcccacc tgagcaccaa ccccaggtta tcttcccctt   3840

tgtcttccag ccccccagaa acagctacga ctcaacctac ccaatcattt catcatcaga   3900

ttgccactgt ctctagttca ggtctcttgg gactggcact cagaaatctc ataataaatc   3960

ctcttgaggc ttctcataca ctcgtcttct tccaatcttc tttccctcaa aatctcatat   4020

tttggttcca cttcacccac cgtcattctc catatcactc ccaggagtta ggcaaaaagc   4080

cccttccgtt cttccgtatg ttaaacttag aatcactctg ttccctgctc tgcgtttcta   4140

ttttttgttt ttcctccatt tactagtagc ttaacacttt ctaacagtgt tcttattatt   4200

gatacgtatc tatctcttcc ataagcttat aaggtcacgg ataatacttc tcattgtagt   4260

acgtaaatga cgtgggctag atatgagttg aataaacagt tatacctgta aattcttaca   4320

gagtgaaaat aaattgttat actttacaat ttgtttctct ctttagacca tttccaggac   4380

ttgtgattaa taaccgtgag tattttgtga agtgttttgt ttttgttttt tcctggggtc   4440

tgacgtgtgt gcgtgtgagt gtgtatacat gcttaacgta tatcacgtta cttcacctat   4500

gtcagtaacc aggccaaata cttgttttag ccctcagtaa aaacaccagg cacttcctag   4560

ttgtaaaatt attcaagctt cttaacttcc tatcctcgat gcacttaatc ataaaatggt   4620

aataatagca ccgattttgg gggagtcgtt ccagtagatg gaaagcatct ggaacaggtg   4680

tcagcaagct cctgccgacg tgtatgcata aagttttatt gaaaccacca tcgtgtccat   4740

ttgtttatgg cagaactgag agatggcagc agcaagtgtg tgcctgcaaa acctaaaata   4800

tttactaatt ggctctgcaa gaaaagagtt tgcatccccc taacctagaa cagtgtctag   4860

cctctagtat gtgtttagcc tacagtatgt gctcagcgaa tacaatctat atttattact   4920

gcttttatga ctgttataat tactgtgctt ggatttcgtt acaaagtaag tcacaatgtg   4980

cctgcttctg ttagtatttc agcacagtgc ctggcacaca tggggctctc aaatattgct   5040

gagcgagtga acaaatgtcc tttcaattcc ttaacgttga tgtcattttc aatagtattt   5100

tgagccaaac ttaattttgc gagtgtgttt tgttttctta actttattat taaaaatgta   5160

taaaagtgag gccaggcgtg gtggctcacg cctgtaatcc cagcagtttg ggaggctgag   5220

gcaggcggat cagttgaggt tgggagttgg agaccagccc gtccaacatg gtgaaagcct   5280

gtctctacta aaaatacaaa aatcagctgg gtgtggtggc gcgtgcctgt aatcccagct   5340

actcaggagg ctgaggcagg agagttgctt gaatcctaga ggtggaggtt gcagtgagct   5400

gagatcgtgc cattgcactc cagcctgggc aacaagagca aaactctgtc ccaataaata   5460

aataaataaa atgttctctt ttgttcctgt tcttgtgcgg tagtgtggta tagagtttta   5520

tggtaattac tgtgaattag tgattctgag ggacatatca gaactctgag gtttgtttcc   5580

ttctcatctt gagggaaaca gcaaatgtat gttaaaatgc ttttccaagg gaacaacaca   5640

tccttacatt atttaaacca atctgcttca ttttcagagc tggttgatca gagtgagtca   5700

gaaggccccg tgatacaaga atcagctgaa ccaagccagt tggaagttcc agccacagaa   5760

gaaataaaag agactgatgg aagctctcag atcaagcaag aaccagaccc cacgtggtag   5820

acctcttccc tcctagggta aatcagcttc tgtgtcaggg atgctgtgtg gtgtccatct   5880

gaaccccctg catacgcgta gctaatgtga tctccccact ttcacataag atggtggccc   5940

tgccttcagg gaatgtggga gccaggtggg agccttcccg gatatttaag ctagaagatt   6000

ctacagggag attctccttg gatcaatata tgtctctcag tcaaagatgt aaaagcactt   6060

ttgccttaaa aagaatgttc tgtttctaaa tagagtcaac gttgtcctcc tcattggaat   6120

tcactatgag tcagaatcat tagactgact tttttttttc catagtaata gtattttgca   6180

gagtctcaca gagctgcaga tcttttgttc atcttgcaga gttaacaagt ctgatcctgt   6240

tagtccagat ttcttaaatt tggccaagtt ataataggag cagtagcttg agacccgaag   6300

tcaggaaact ttgacaatgg attttttttt ttaatccaga gacttgtact ggaatttgcc   6360

ttaccctgtc agctcatgga cttaaggttt catcccgctt tatgagtgct tctgaatcca   6420

agtcattgtt acctgaattt gcaaattaag ttgtgatatt cgtgactgtt aaattcctgt   6480

aattagatta acctctttgc ttgcttgttt gttttctctc ctattttagc ttaaagtatc   6540

agtggttgag aagagctttt cggacctgtt actaccccaa gctgtgtaat atacttgtat   6600

aacagaaata ccttctatac aaaccttttt ttctactttt agatagaaat gtctactttt   6660

tcagcagttc tgtgaattaa agagcagagt gactgtgggt ctggaatggc tggtgtactt   6720

gggaatgtac tatcaggatt ttacagcaat gctgggaaat gacagggaaa atgacaggaa   6780

tgaatctcac cagatttttt atgtactcag cagagccttg agttacggtg tttattttcc   6840

aatcaagtga agatatctcc tacttctcct actggaacat ctcagcttct gcagtgaaga   6900

aaaattcctg tgatagttca gttctttagt ttttctattt gaaaaaaaaa aatcatttaa   6960

atgatccttt gttcacggct ctccttaatg actgagtgaa cagttcctat ctgtatattt   7020

gactaaacct tttcctaagc tatctctcat ggttcctatg tttttttatc ataattaaaa   7080

gcaaaaccat ctggatcacc taacagtcag aggtcagtat ctcagcgtgt gaattataga   7140

ggaaatacag agagaacctc ttccactttt acttttcgtc caaataaaat gcatggtgta   7200

ccagaagttg aagatcgggt tgaggattgg ggctagctcg atgacactaa ggccccaaca   7260

tcgcgggacc tgctgtggcg cggattctta ggaacgctgt tctagccggc cccctctcca   7320

ggggtcgccg tggccggcat tatttcctag ttcttcttgt aaccctgagg tgccagcgcg   7380

gggagtgagg aggggtcagg gggctaagga tgcaacctct gacgttctgc gccttcctag   7440

gagagtctta catgtgttga gatttcacaa gcaatgcgag ttgtaaaata ccagctctac   7500

aagaagctag gctctgtgac ggcatagttt tcagtagctt tatcacaata ttcacaatgg   7560

agaattatat gacatggtag cagaaatagg cccttttatg tgttgcttct attttacctc   7620

aaattgtaga tatagggtaa tcaataaaat ccatccatgc ctttcacaca ctaagt       7676


<210>  5241
<211>  877
<212>  PRT
<213>  Homo sapiens

<400>  5241

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly Leu Thr Glu Ala Val 
        515                 520                 525


Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val 
    530                 535                 540


Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly 
545                 550                 555                 560


Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe 
                565                 570                 575


Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met 
            580                 585                 590


Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg 
        595                 600                 605


Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu 
    610                 615                 620


Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr 
625                 630                 635                 640


Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe 
                645                 650                 655


Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val 
            660                 665                 670


Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln 
        675                 680                 685


Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe 
    690                 695                 700


Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr 
705                 710                 715                 720


Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile 
                725                 730                 735


Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu 
            740                 745                 750


Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn 
        755                 760                 765


Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val 
    770                 775                 780


Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala 
785                 790                 795                 800


Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly 
                805                 810                 815


Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile 
            820                 825                 830


Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val 
        835                 840                 845


Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile 
    850                 855                 860


Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile Arg 
865                 870                 875


<210>  5242
<211>  3739
<212>  DNA
<213>  Homo sapiens

<400>  5242
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2040

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2100

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2160

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2220

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2280

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2340

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2400

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2460

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2520

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2580

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2640

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2700

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2760

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2820

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2880

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   2940

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3000

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3060

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3120

gtggtagacc tcttccctcc taggcaaaac catctggatc acctaacagt cagaggtcag   3180

tatctcagcg tgtgaattat agaggaaata cagagagaac ctcttccact tttacttttc   3240

gtccaaataa aatgcatggt gtaccagaag ttgaagatcg ggttgaggat tggggctagc   3300

tcgatgacac taaggcccca acatcgcggg acctgctgtg gcgcggattc ttaggaacgc   3360

tgttctagcc ggccccctct ccaggggtcg ccgtggccgg cattatttcc tagttcttct   3420

tgtaaccctg aggtgccagc gcggggagtg aggaggggtc agggggctaa ggatgcaacc   3480

tctgacgttc tgcgccttcc taggagagtc ttacatgtgt tgagatttca caagcaatgc   3540

gagttgtaaa ataccagctc tacaagaagc taggctctgt gacggcatag ttttcagtag   3600

ctttatcaca atattcacaa tggagaatta tatgacatgg tagcagaaat aggccctttt   3660

atgtgttgct tctattttac ctcaaattgt agatataggg taatcaataa aatccatcca   3720

tgcctttcac acactaagt                                                3739


<210>  5243
<211>  605
<212>  PRT
<213>  Homo sapiens

<400>  5243

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala 
            580                 585                 590


Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600                 605


<210>  5244
<211>  4011
<212>  DNA
<213>  Homo sapiens

<400>  5244
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1860

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1920

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   1980

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2040

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2100

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2160

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2220

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2280

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2340

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2400

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2460

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2520

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2580

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2640

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2700

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2760

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2820

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2880

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   2940

tcaaattcac ggtcattaga ccatttccag gacttgtgat taataaccag ctggttgatc   3000

agagtgagtc agaaggcccc gtgatacaag aatcagctga accaagccag ttggaagttc   3060

cagccacaga agaaataaaa gagactgatg gaagctctca gatcaagcaa gaaccagacc   3120

ccacgtggta gacctcttcc ctcctaggag ccttgagtta cggtgtttat tttccaatca   3180

agtgaagata tctcctactt ctcctactgg aacatctcag cttctgcagt gaagaaaaat   3240

tcctgtgata gttcagttct ttagtttttc tatttgaaaa aaaaaaatca tttaaatgat   3300

cctttgttca cggctctcct taatgactga gtgaacagtt cctatctgta tatttgacta   3360

aaccttttcc taagctatct ctcatggttc ctatgttttt ttatcataat taaaagcaaa   3420

accatctgga tcacctaaca gtcagaggtc agtatctcag cgtgtgaatt atagaggaaa   3480

tacagagaga acctcttcca cttttacttt tcgtccaaat aaaatgcatg gtgtaccaga   3540

agttgaagat cgggttgagg attggggcta gctcgatgac actaaggccc caacatcgcg   3600

ggacctgctg tggcgcggat tcttaggaac gctgttctag ccggccccct ctccaggggt   3660

cgccgtggcc ggcattattt cctagttctt cttgtaaccc tgaggtgcca gcgcggggag   3720

tgaggagggg tcagggggct aaggatgcaa cctctgacgt tctgcgcctt cctaggagag   3780

tcttacatgt gttgagattt cacaagcaat gcgagttgta aaataccagc tctacaagaa   3840

gctaggctct gtgacggcat agttttcagt agctttatca caatattcac aatggagaat   3900

tatatgacat ggtagcagaa ataggccctt ttatgtgttg cttctatttt acctcaaatt   3960

gtagatatag ggtaatcaat aaaatccatc catgcctttc acacactaag t            4011


<210>  5245
<211>  957
<212>  PRT
<213>  Homo sapiens

<400>  5245

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr 
        515                 520                 525


Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln 
    530                 535                 540


Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu 
545                 550                 555                 560


Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro 
                565                 570                 575


Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val 
            580                 585                 590


Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val 
        595                 600                 605


Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala 
    610                 615                 620


Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val 
625                 630                 635                 640


Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln 
                645                 650                 655


Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro 
            660                 665                 670


Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys 
        675                 680                 685


Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys 
    690                 695                 700


Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu 
705                 710                 715                 720


Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly 
                725                 730                 735


Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys 
            740                 745                 750


Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu 
        755                 760                 765


Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro 
    770                 775                 780


Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val 
785                 790                 795                 800


Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu 
                805                 810                 815


Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn 
            820                 825                 830


Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro 
        835                 840                 845


Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val 
    850                 855                 860


Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu 
865                 870                 875                 880


Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys 
                885                 890                 895


Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu 
            900                 905                 910


Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu 
        915                 920                 925


Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp 
    930                 935                 940


Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950                 955


<210>  5246
<211>  4983
<212>  DNA
<213>  Homo sapiens

<400>  5246
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2040

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2100

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2160

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2220

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2280

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2340

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2400

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2460

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2520

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2580

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2640

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2700

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2760

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2820

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2880

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   2940

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3000

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3060

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3120

gtggtagacc tcttccctcc tagggtaaat cagcttctgt gtcagggatg ctgtgtggtg   3180

tccatctgaa ccccctgcat acgcgtagct aatgtgatct ccccactttc acataagatg   3240

gtggccctgc cttcagggaa tgtgggagcc aggtgggagc cttcccggat atttaagcta   3300

gaagattcta cagggagatt ctccttggat caatatatgt ctctcagtca aagatgtaaa   3360

agcacttttg ccttaaaaag aatgttctgt ttctaaatag agtcaacgtt gtcctcctca   3420

ttggaattca ctatgagtca gaatcattag actgactttt ttttttccat agtaatagta   3480

ttttgcagag tctcacagag ctgcagatct tttgttcatc ttgcagagtt aacaagtctg   3540

atcctgttag tccagatttc ttaaatttgg ccaagttata ataggagcag tagcttgaga   3600

cccgaagtca ggaaactttg acaatggatt ttttttttta atccagagac ttgtactgga   3660

atttgcctta ccctgtcagc tcatggactt aaggtttcat cccgctttat gagtgcttct   3720

gaatccaagt cattgttacc tgaatttgca aattaagttg tgatattcgt gactgttaaa   3780

ttcctgtaat tagattaacc tctttgcttg cttgtttgtt ttctctccta ttttagctta   3840

aagtatcagt ggttgagaag agcttttcgg acctgttact accccaagct gtgtaatata   3900

cttgtataac agaaatacct tctatacaaa cctttttttc tacttttaga tagaaatgtc   3960

tactttttca gcagttctgt gaattaaaga gcagagtgac tgtgggtctg gaatggctgg   4020

tgtacttggg aatgtactat caggatttta cagcaatgct gggaaatgac agggaaaatg   4080

acaggaatga atctcaccag attttttatg tactcagcag agccttgagt tacggtgttt   4140

attttccaat caagtgaaga tatctcctac ttctcctact ggaacatctc agcttctgca   4200

gtgaagaaaa attcctgtga tagttcagtt ctttagtttt tctatttgaa aaaaaaaaat   4260

catttaaatg atcctttgtt cacggctctc cttaatgact gagtgaacag ttcctatctg   4320

tatatttgac taaacctttt cctaagctat ctctcatggt tcctatgttt ttttatcata   4380

attaaaagca aaaccatctg gatcacctaa cagtcagagg tcagtatctc agcgtgtgaa   4440

ttatagagga aatacagaga gaacctcttc cacttttact tttcgtccaa ataaaatgca   4500

tggtgtacca gaagttgaag atcgggttga ggattggggc tagctcgatg acactaaggc   4560

cccaacatcg cgggacctgc tgtggcgcgg attcttagga acgctgttct agccggcccc   4620

ctctccaggg gtcgccgtgg ccggcattat ttcctagttc ttcttgtaac cctgaggtgc   4680

cagcgcgggg agtgaggagg ggtcaggggg ctaaggatgc aacctctgac gttctgcgcc   4740

ttcctaggag agtcttacat gtgttgagat ttcacaagca atgcgagttg taaaatacca   4800

gctctacaag aagctaggct ctgtgacggc atagttttca gtagctttat cacaatattc   4860

acaatggaga attatatgac atggtagcag aaataggccc ttttatgtgt tgcttctatt   4920

ttacctcaaa ttgtagatat agggtaatca ataaaatcca tccatgcctt tcacacacta   4980

agt                                                                 4983


<210>  5247
<211>  605
<212>  PRT
<213>  Homo sapiens

<400>  5247

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala 
            580                 585                 590


Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600                 605


<210>  5248
<211>  3840
<212>  DNA
<213>  Homo sapiens

<400>  5248
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggaagccac cattcttcag    960

agggcaatga aggcacagaa atggaagtac cagcagaaga ttctactcaa catgtccctt   1020

cagaaacaag tgaggaccct gaagttgagg tgactattga agatgatgat tattctccac   1080

cgtctaagag accaaaggcc aatgagctac cgcagccacc agtcccggaa cccgccaatg   1140

ctgggaagcg gaaagtgagg gagttcaact tcgagaaatg gaatgctcgc atcactgatc   1200

tacgtaaaca agttgaagaa ttgtttgaaa ggaaatatgc tcaagccata aaagccaaag   1260

gtccggtgac gatcccgtac cctcttttcc agtctcatgt tgaagatctt tatgtagaag   1320

gacttcctga aggaattcct tttagaaggc catctactta cggaattcct cgcctggaga   1380

ggatattact tgcaaaggaa aggattcgtt ttgtgattaa gaaacatgag cttctgaatt   1440

caacacgtga agatttacag cttgataagc cagcttcagg agtaaaggaa gaatggtatg   1500

ccagaatcac taaattaaga aagatggtgg atcagctttt ctgcaaaaaa tttgcggaag   1560

ccttggggag cactgaagcc aaggctgtac cgtaccaaaa atttgaggca cacccgaatg   1620

atctgtacgt ggaaggactg ccagaaaaca ttcctttccg aagtccctca tggtatggaa   1680

tcccaaggct ggaaaaaatc attcaagtgg gcaatcgaat taaatttgtt attaaaagac   1740

cagaacttct gactcacagt accactgaag ttactcagcc aagaacgaat acaccagtca   1800

aagaagattg gaatgtcaga attaccaagc tacggaagca agtggaagag atttttaatt   1860

tgaaatttgc ttagatttgt tgacagcggt ttcctggagt gctgtcttga gaacgattct   1920

gaggaggctc agcaagaaag agtgtttcag ttgattgggt gtgtctgtca tggagaagga   1980

actcaagctc ttggactcac cgaggcagta aaagtaccat atcctgtgtt tgaatcaaac   2040

ccggagttct tgtatgtgga aggcttgcca gaggggattc ccttccgaag ccctacctgg   2100

tttggaattc cacgacttga aaggatcgtc cgcgggagta ataaaatcaa gttcgttgtt   2160

aaaaaacctg aactagttat ttcctacttg cctcctggga tggctagtaa aataaacact   2220

aaagctttgc agtcccccaa aagaccacga agtcctggga gtaattcaaa ggttcctgaa   2280

attgaggtca ccgtggaagg ccctaataac aacaatcctc aaacctcagc tgttcgaacc   2340

ccgacccaga ctaacggttc taacgttccc ttcaagccac gagggagaga gttttccttt   2400

gaggcctgga atgccaaaat cacggaccta aaacagaaag ttgaaaatct cttcaatgag   2460

aaatgtgggg aagctcttgg ccttaaacaa gctgtgaagg tgccgttcgc gttatttgag   2520

tctttcccgg aagactttta tgtggaaggc ttacctgagg gtgtgccatt ccgaagacca   2580

tcgacttttg gcattccgag gctggagaag atactcagaa acaaagccaa aattaagttc   2640

atcattaaaa agcccgaaat gtttgagacg gcgattaagg agagcacctc ctctaagagc   2700

cctcccagaa aaataaattc atcacccaat gttaatacta ctgcatcagg tgttgaagac   2760

cttaacatca ttcaggtgac aattccagat gatgataatg aaagactctc gaaagttgaa   2820

aaagctagac agctaagaga acaagtgaat gacctcttta gtcggaaatt tggtgaagct   2880

attggtatgg gttttcctgt gaaagttccc tacaggaaaa tcacaattaa ccctggctgt   2940

gtggtggttg atggcatgcc cccgggggtg tccttcaaag cccccagcta cctggaaatc   3000

agctccatga gaaggatctt agactctgcc gagtttatca aattcacggt cattagacca   3060

tttccaggac ttgtgattaa taaccagctg gttgatcaga gtgagtcaga aggccccgtg   3120

atacaagaat cagctgaacc aagccagttg gaagttccag ccacagaaga aataaaagag   3180

actgatggaa gctctcagat caagcaagaa ccagacccca cgtggtagac ctcttccctc   3240

ctaggcaaaa ccatctggat cacctaacag tcagaggtca gtatctcagc gtgtgaatta   3300

tagaggaaat acagagagaa cctcttccac ttttactttt cgtccaaata aaatgcatgg   3360

tgtaccagaa gttgaagatc gggttgagga ttggggctag ctcgatgaca ctaaggcccc   3420

aacatcgcgg gacctgctgt ggcgcggatt cttaggaacg ctgttctagc cggccccctc   3480

tccaggggtc gccgtggccg gcattatttc ctagttcttc ttgtaaccct gaggtgccag   3540

cgcggggagt gaggaggggt cagggggcta aggatgcaac ctctgacgtt ctgcgccttc   3600

ctaggagagt cttacatgtg ttgagatttc acaagcaatg cgagttgtaa aataccagct   3660

ctacaagaag ctaggctctg tgacggcata gttttcagta gctttatcac aatattcaca   3720

atggagaatt atatgacatg gtagcagaaa taggcccttt tatgtgttgc ttctatttta   3780

cctcaaattg tagatatagg gtaatcaata aaatccatcc atgcctttca cacactaagt   3840


<210>  5249
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  5249

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr 
225                 230                 235                 240


Glu Met Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu 
                245                 250                 255


Thr Ser Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr 
            260                 265                 270


Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro 
        275                 280                 285


Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn 
    290                 295                 300


Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu 
305                 310                 315                 320


Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro 
                325                 330                 335


Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr 
            340                 345                 350


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr 
        355                 360                 365


Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg 
    370                 375                 380


Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu 
385                 390                 395                 400


Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg 
                405                 410                 415


Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe 
            420                 425                 430


Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys 
        435                 440                 445


Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn 
    450                 455                 460


Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys 
465                 470                 475                 480


Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu 
                485                 490                 495


Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr 
            500                 505                 510


Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln 
        515                 520                 525


Val Glu Glu Ile Phe Asn Leu Lys Phe Ala 
    530                 535


<210>  5250
<211>  3855
<212>  DNA
<213>  Homo sapiens

<400>  5250
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1860

aagagatttt taatttgaaa tttgcttaga tttgttgaca gcggtttcct ggagtgctgt   1920

cttgagaacg attctgagga ggctcagcaa gaaagagtgt ttcagttgat tgggtgtgtc   1980

tgtcatggag aaggaactca agctcttgga ctcaccgagg cagtaaaagt accatatcct   2040

gtgtttgaat caaacccgga gttcttgtat gtggaaggct tgccagaggg gattcccttc   2100

cgaagcccta cctggtttgg aattccacga cttgaaagga tcgtccgcgg gagtaataaa   2160

atcaagttcg ttgttaaaaa acctgaacta gttatttcct acttgcctcc tgggatggct   2220

agtaaaataa acactaaagc tttgcagtcc cccaaaagac cacgaagtcc tgggagtaat   2280

tcaaaggttc ctgaaattga ggtcaccgtg gaaggcccta ataacaacaa tcctcaaacc   2340

tcagctgttc gaaccccgac ccagactaac ggttctaacg ttcccttcaa gccacgaggg   2400

agagagtttt cctttgaggc ctggaatgcc aaaatcacgg acctaaaaca gaaagttgaa   2460

aatctcttca atgagaaatg tggggaagct cttggcctta aacaagctgt gaaggtgccg   2520

ttcgcgttat ttgagtcttt cccggaagac ttttatgtgg aaggcttacc tgagggtgtg   2580

ccattccgaa gaccatcgac ttttggcatt ccgaggctgg agaagatact cagaaacaaa   2640

gccaaaatta agttcatcat taaaaagccc gaaatgtttg agacggcgat taaggagagc   2700

acctcctcta agagccctcc cagaaaaata aattcatcac ccaatgttaa tactactgca   2760

tcaggtgttg aagaccttaa catcattcag gtgacaattc cagatgatga taatgaaaga   2820

ctctcgaaag ttgaaaaagc tagacagcta agagaacaag tgaatgacct ctttagtcgg   2880

aaatttggtg aagctattgg tatgggtttt cctgtgaaag ttccctacag gaaaatcaca   2940

attaaccctg gctgtgtggt ggttgatggc atgcccccgg gggtgtcctt caaagccccc   3000

agctacctgg aaatcagctc catgagaagg atcttagact ctgccgagtt tatcaaattc   3060

acggtcatta gaccatttcc aggacttgtg attaataacc agctggttga tcagagtgag   3120

tcagaaggcc ccgtgataca agaatcagct gaaccaagcc agttggaagt tccagccaca   3180

gaagaaataa aagagactga tggaagctct cagatcaagc aagaaccaga ccccacgtgg   3240

tagacctctt ccctcctagg caaaaccatc tggatcacct aacagtcaga ggtcagtatc   3300

tcagcgtgtg aattatagag gaaatacaga gagaacctct tccactttta cttttcgtcc   3360

aaataaaatg catggtgtac cagaagttga agatcgggtt gaggattggg gctagctcga   3420

tgacactaag gccccaacat cgcgggacct gctgtggcgc ggattcttag gaacgctgtt   3480

ctagccggcc ccctctccag gggtcgccgt ggccggcatt atttcctagt tcttcttgta   3540

accctgaggt gccagcgcgg ggagtgagga ggggtcaggg ggctaaggat gcaacctctg   3600

acgttctgcg ccttcctagg agagtcttac atgtgttgag atttcacaag caatgcgagt   3660

tgtaaaatac cagctctaca agaagctagg ctctgtgacg gcatagtttt cagtagcttt   3720

atcacaatat tcacaatgga gaattatatg acatggtagc agaaataggc ccttttatgt   3780

gttgcttcta ttttacctca aattgtagat atagggtaat caataaaatc catccatgcc   3840

tttcacacac taagt                                                    3855


<210>  5251
<211>  543
<212>  PRT
<213>  Homo sapiens

<400>  5251

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr 
        515                 520                 525


Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu Lys Phe Ala 
    530                 535                 540


<210>  5252
<211>  5110
<212>  DNA
<213>  Homo sapiens

<400>  5252
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1980

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   2040

taccatatcc tgtgtttgaa tcaaacccgg agttcttgta tgtggaaggc ttgccagagg   2100

ggattccctt ccgaagccct acctggtttg gaattccacg acttgaaagg atcgtccgcg   2160

ggagtaataa aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc   2220

ctgggatggc tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc   2280

ctgggagtaa ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca   2340

atcctcaaac ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca   2400

agccacgagg gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac   2460

agaaagttga aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg   2520

tgaaggtgcc gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac   2580

ctgagggtgt gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac   2640

tcagaaacaa agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga   2700

ttaaggagag cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta   2760

atactactgc atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg   2820

ataatgaaag actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc   2880

tctttagtcg gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca   2940

ggaaaatcac aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct   3000

tcaaagcccc cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt   3060

ttatcaaatt cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg   3120

atcagagtga gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag   3180

ttccagccac agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag   3240

accccacgtg gtagacctct tccctcctag ggtaaatcag cttctgtgtc agggatgctg   3300

tgtggtgtcc atctgaaccc cctgcatacg cgtagctaat gtgatctccc cactttcaca   3360

taagatggtg gccctgcctt cagggaatgt gggagccagg tgggagcctt cccggatatt   3420

taagctagaa gattctacag ggagattctc cttggatcaa tatatgtctc tcagtcaaag   3480

atgtaaaagc acttttgcct taaaaagaat gttctgtttc taaatagagt caacgttgtc   3540

ctcctcattg gaattcacta tgagtcagaa tcattagact gacttttttt tttccatagt   3600

aatagtattt tgcagagtct cacagagctg cagatctttt gttcatcttg cagagttaac   3660

aagtctgatc ctgttagtcc agatttctta aatttggcca agttataata ggagcagtag   3720

cttgagaccc gaagtcagga aactttgaca atggattttt ttttttaatc cagagacttg   3780

tactggaatt tgccttaccc tgtcagctca tggacttaag gtttcatccc gctttatgag   3840

tgcttctgaa tccaagtcat tgttacctga atttgcaaat taagttgtga tattcgtgac   3900

tgttaaattc ctgtaattag attaacctct ttgcttgctt gtttgttttc tctcctattt   3960

tagcttaaag tatcagtggt tgagaagagc ttttcggacc tgttactacc ccaagctgtg   4020

taatatactt gtataacaga aataccttct atacaaacct ttttttctac ttttagatag   4080

aaatgtctac tttttcagca gttctgtgaa ttaaagagca gagtgactgt gggtctggaa   4140

tggctggtgt acttgggaat gtactatcag gattttacag caatgctggg aaatgacagg   4200

gaaaatgaca ggaatgaatc tcaccagatt ttttatgtac tcagcagagc cttgagttac   4260

ggtgtttatt ttccaatcaa gtgaagatat ctcctacttc tcctactgga acatctcagc   4320

ttctgcagtg aagaaaaatt cctgtgatag ttcagttctt tagtttttct atttgaaaaa   4380

aaaaaatcat ttaaatgatc ctttgttcac ggctctcctt aatgactgag tgaacagttc   4440

ctatctgtat atttgactaa accttttcct aagctatctc tcatggttcc tatgtttttt   4500

tatcataatt aaaagcaaaa ccatctggat cacctaacag tcagaggtca gtatctcagc   4560

gtgtgaatta tagaggaaat acagagagaa cctcttccac ttttactttt cgtccaaata   4620

aaatgcatgg tgtaccagaa gttgaagatc gggttgagga ttggggctag ctcgatgaca   4680

ctaaggcccc aacatcgcgg gacctgctgt ggcgcggatt cttaggaacg ctgttctagc   4740

cggccccctc tccaggggtc gccgtggccg gcattatttc ctagttcttc ttgtaaccct   4800

gaggtgccag cgcggggagt gaggaggggt cagggggcta aggatgcaac ctctgacgtt   4860

ctgcgccttc ctaggagagt cttacatgtg ttgagatttc acaagcaatg cgagttgtaa   4920

aataccagct ctacaagaag ctaggctctg tgacggcata gttttcagta gctttatcac   4980

aatattcaca atggagaatt atatgacatg gtagcagaaa taggcccttt tatgtgttgc   5040

ttctatttta cctcaaattg tagatatagg gtaatcaata aaatccatcc atgcctttca   5100

cacactaagt                                                          5110


<210>  5253
<211>  998
<212>  PRT
<213>  Homo sapiens

<400>  5253

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val 
545                 550                 555                 560


Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu 
                565                 570                 575


Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala 
            580                 585                 590


Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr 
        595                 600                 605


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe 
    610                 615                 620


Gly Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys 
625                 630                 635                 640


Phe Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly 
                645                 650                 655


Met Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro 
            660                 665                 670


Arg Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val 
        675                 680                 685


Glu Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro 
    690                 695                 700


Thr Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu 
705                 710                 715                 720


Phe Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys 
                725                 730                 735


Val Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys 
            740                 745                 750


Gln Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp 
        755                 760                 765


Phe Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser 
    770                 775                 780


Thr Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys 
785                 790                 795                 800


Ile Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys 
                805                 810                 815


Glu Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro 
            820                 825                 830


Asn Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln 
        835                 840                 845


Val Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys 
    850                 855                 860


Ala Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe 
865                 870                 875                 880


Gly Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys 
                885                 890                 895


Ile Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly 
            900                 905                 910


Val Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg 
        915                 920                 925


Ile Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe 
    930                 935                 940


Pro Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu 
945                 950                 955                 960


Gly Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro 
                965                 970                 975


Ala Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln 
            980                 985                 990


Glu Pro Asp Pro Thr Trp 
        995


<210>  5254
<211>  4067
<212>  DNA
<213>  Homo sapiens

<400>  5254
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1860

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1920

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   1980

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2040

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2100

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2160

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2220

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2280

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2340

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2400

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2460

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2520

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2580

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2640

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2700

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2760

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2820

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2880

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   2940

tcaaattcac ggtcattaga ccatttccag gacttgtgat taataaccag ctggttgatc   3000

agagtgagtc agaaggcccc gtgatacaag aatcagctga accaagccag ttggaagttc   3060

cagccacaga agaaataaaa gagactgatg gaagctctca gatcaagcaa gaaccagacc   3120

ccacgtggta gacctcttcc ctcctaggct taaagtatca gtggttgaga agagcttttc   3180

ggacctgtta ctaccccaag ctgtagcctt gagttacggt gtttattttc caatcaagtg   3240

aagatatctc ctacttctcc tactggaaca tctcagcttc tgcagtgaag aaaaattcct   3300

gtgatagttc agttctttag tttttctatt tgaaaaaaaa aaatcattta aatgatcctt   3360

tgttcacggc tctccttaat gactgagtga acagttccta tctgtatatt tgactaaacc   3420

ttttcctaag ctatctctca tggttcctat gtttttttat cataattaaa agcaaaacca   3480

tctggatcac ctaacagtca gaggtcagta tctcagcgtg tgaattatag aggaaataca   3540

gagagaacct cttccacttt tacttttcgt ccaaataaaa tgcatggtgt accagaagtt   3600

gaagatcggg ttgaggattg gggctagctc gatgacacta aggccccaac atcgcgggac   3660

ctgctgtggc gcggattctt aggaacgctg ttctagccgg ccccctctcc aggggtcgcc   3720

gtggccggca ttatttccta gttcttcttg taaccctgag gtgccagcgc ggggagtgag   3780

gaggggtcag ggggctaagg atgcaacctc tgacgttctg cgccttccta ggagagtctt   3840

acatgtgttg agatttcaca agcaatgcga gttgtaaaat accagctcta caagaagcta   3900

ggctctgtga cggcatagtt ttcagtagct ttatcacaat attcacaatg gagaattata   3960

tgacatggta gcagaaatag gcccttttat gtgttgcttc tattttacct caaattgtag   4020

atatagggta atcaataaaa tccatccatg cctttcacac actaagt                 4067


<210>  5255
<211>  957
<212>  PRT
<213>  Homo sapiens

<400>  5255

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr 
        515                 520                 525


Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln 
    530                 535                 540


Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu 
545                 550                 555                 560


Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro 
                565                 570                 575


Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val 
            580                 585                 590


Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val 
        595                 600                 605


Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala 
    610                 615                 620


Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val 
625                 630                 635                 640


Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln 
                645                 650                 655


Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro 
            660                 665                 670


Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys 
        675                 680                 685


Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys 
    690                 695                 700


Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu 
705                 710                 715                 720


Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly 
                725                 730                 735


Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys 
            740                 745                 750


Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu 
        755                 760                 765


Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro 
    770                 775                 780


Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val 
785                 790                 795                 800


Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu 
                805                 810                 815


Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn 
            820                 825                 830


Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro 
        835                 840                 845


Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val 
    850                 855                 860


Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu 
865                 870                 875                 880


Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys 
                885                 890                 895


Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu 
            900                 905                 910


Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu 
        915                 920                 925


Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp 
    930                 935                 940


Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950                 955


<210>  5256
<211>  4302
<212>  DNA
<213>  Homo sapiens

<400>  5256
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1980

tggaagagat ttttaatttg aaatttgctt agatttgttg acagcggttt cctggagtgc   2040

tgtcttgaga acgattctga ggaggctcag caagaaagag tgtttcagtt gattgggtgt   2100

gtctgtcatg gagaaggaac tcaagctctt ggactcaccg aggcagtaaa agtaccatat   2160

cctgtgtttg aatcaaaccc ggagttcttg tatgtggaag gcttgccaga ggggattccc   2220

ttccgaagcc ctacctggtt tggaattcca cgacttgaaa ggatcgtccg cgggagtaat   2280

aaaatcaagt tcgttgttaa aaaacctgaa ctagttattt cctacttgcc tcctgggatg   2340

gctagtaaaa taaacactaa agctttgcag tcccccaaaa gaccacgaag tcctgggagt   2400

aattcaaagg ttcctgaaat tgaggtcacc gtggaaggcc ctaataacaa caatcctcaa   2460

acctcagctg ttcgaacccc gacccagact aacggttcta acgttccctt caagccacga   2520

gggagagagt tttcctttga ggcctggaat gccaaaatca cggacctaaa acagaaagtt   2580

gaaaatctct tcaatgagaa atgtggggaa gctcttggcc ttaaacaagc tgtgaaggtg   2640

ccgttcgcgt tatttgagtc tttcccggaa gacttttatg tggaaggctt acctgagggt   2700

gtgccattcc gaagaccatc gacttttggc attccgaggc tggagaagat actcagaaac   2760

aaagccaaaa ttaagttcat cattaaaaag cccgaaatgt ttgagacggc gattaaggag   2820

agcacctcct ctaagagccc tcccagaaaa ataaattcat cacccaatgt taatactact   2880

gcatcaggtg ttgaagacct taacatcatt caggtgacaa ttccagatga tgataatgaa   2940

agactctcga aagttgaaaa agctagacag ctaagagaac aagtgaatga cctctttagt   3000

cggaaatttg gtgaagctat tggtatgggt tttcctgtga aagttcccta caggaaaatc   3060

acaattaacc ctggctgtgt ggtggttgat ggcatgcccc cgggggtgtc cttcaaagcc   3120

cccagctacc tggaaatcag ctccatgaga aggatcttag actctgccga gtttatcaaa   3180

ttcacggtca ttagaccatt tccaggactt gtgattaata accagctggt tgatcagagt   3240

gagtcagaag gccccgtgat acaagaatca gctgaaccaa gccagttgga agttccagcc   3300

acagaagaaa taaaagagac tgatggaagc tctcagatca agcaagaacc agaccccacg   3360

tggtagacct cttccctcct aggcttaaag tatcagtggt tgagaagagc ttttcggacc   3420

tgttactacc ccaagctgta gccttgagtt acggtgttta ttttccaatc aagtgaagat   3480

atctcctact tctcctactg gaacatctca gcttctgcag tgaagaaaaa ttcctgtgat   3540

agttcagttc tttagttttt ctatttgaaa aaaaaaaatc atttaaatga tcctttgttc   3600

acggctctcc ttaatgactg agtgaacagt tcctatctgt atatttgact aaaccttttc   3660

ctaagctatc tctcatggtt cctatgtttt tttatcataa ttaaaagcaa aaccatctgg   3720

atcacctaac agtcagaggt cagtatctca gcgtgtgaat tatagaggaa atacagagag   3780

aacctcttcc acttttactt ttcgtccaaa taaaatgcat ggtgtaccag aagttgaaga   3840

tcgggttgag gattggggct agctcgatga cactaaggcc ccaacatcgc gggacctgct   3900

gtggcgcgga ttcttaggaa cgctgttcta gccggccccc tctccagggg tcgccgtggc   3960

cggcattatt tcctagttct tcttgtaacc ctgaggtgcc agcgcgggga gtgaggaggg   4020

gtcagggggc taaggatgca acctctgacg ttctgcgcct tcctaggaga gtcttacatg   4080

tgttgagatt tcacaagcaa tgcgagttgt aaaataccag ctctacaaga agctaggctc   4140

tgtgacggca tagttttcag tagctttatc acaatattca caatggagaa ttatatgaca   4200

tggtagcaga aataggccct tttatgtgtt gcttctattt tacctcaaat tgtagatata   4260

gggtaatcaa taaaatccat ccatgccttt cacacactaa gt                      4302


<210>  5257
<211>  584
<212>  PRT
<213>  Homo sapiens

<400>  5257

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val 
545                 550                 555                 560


Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu 
                565                 570                 575


Glu Ile Phe Asn Leu Lys Phe Ala 
            580


<210>  5258
<211>  4000
<212>  DNA
<213>  Homo sapiens

<400>  5258
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1860

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1920

catatcctgt gtttgaatca aacccggagt tcttgaaagg atcgtccgcg ggagtaataa   1980

aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc ctgggatggc   2040

tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc ctgggagtaa   2100

ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca atcctcaaac   2160

ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca agccacgagg   2220

gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac agaaagttga   2280

aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg tgaaggtgcc   2340

gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac ctgagggtgt   2400

gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac tcagaaacaa   2460

agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga ttaaggagag   2520

cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta atactactgc   2580

atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg ataatgaaag   2640

actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc tctttagtcg   2700

gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca ggaaaatcac   2760

aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct tcaaagcccc   2820

cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt ttatcaaatt   2880

cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg atcagagtga   2940

gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag ttccagccac   3000

agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag accccacgtg   3060

gtagacctct tccctcctag gcttaaagta tcagtggttg agaagagctt ttcggacctg   3120

ttactacccc aagctgtagc cttgagttac ggtgtttatt ttccaatcaa gtgaagatat   3180

ctcctacttc tcctactgga acatctcagc ttctgcagtg aagaaaaatt cctgtgatag   3240

ttcagttctt tagtttttct atttgaaaaa aaaaaatcat ttaaatgatc ctttgttcac   3300

ggctctcctt aatgactgag tgaacagttc ctatctgtat atttgactaa accttttcct   3360

aagctatctc tcatggttcc tatgtttttt tatcataatt aaaagcaaaa ccatctggat   3420

cacctaacag tcagaggtca gtatctcagc gtgtgaatta tagaggaaat acagagagaa   3480

cctcttccac ttttactttt cgtccaaata aaatgcatgg tgtaccagaa gttgaagatc   3540

gggttgagga ttggggctag ctcgatgaca ctaaggcccc aacatcgcgg gacctgctgt   3600

ggcgcggatt cttaggaacg ctgttctagc cggccccctc tccaggggtc gccgtggccg   3660

gcattatttc ctagttcttc ttgtaaccct gaggtgccag cgcggggagt gaggaggggt   3720

cagggggcta aggatgcaac ctctgacgtt ctgcgccttc ctaggagagt cttacatgtg   3780

ttgagatttc acaagcaatg cgagttgtaa aataccagct ctacaagaag ctaggctctg   3840

tgacggcata gttttcagta gctttatcac aatattcaca atggagaatt atatgacatg   3900

gtagcagaaa taggcccttt tatgtgttgc ttctatttta cctcaaattg tagatatagg   3960

gtaatcaata aaatccatcc atgcctttca cacactaagt                         4000


<210>  5259
<211>  584
<212>  PRT
<213>  Homo sapiens

<400>  5259

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr 
        515                 520                 525


Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln 
    530                 535                 540


Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu 
545                 550                 555                 560


Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala Gly Val Ile Lys Ser 
                565                 570                 575


Ser Ser Leu Leu Lys Asn Leu Asn 
            580


<210>  5260
<211>  4999
<212>  DNA
<213>  Homo sapiens

<400>  5260
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgta tgtggaaggc ttgccagagg   2040

ggattccctt ccgaagccct acctggtttg gaattccacg acttgaaagg atcgtccgcg   2100

ggagtaataa aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc   2160

ctgggatggc tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc   2220

ctgggagtaa ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca   2280

atcctcaaac ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca   2340

agccacgagg gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac   2400

agaaagttga aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg   2460

tgaaggtgcc gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac   2520

ctgagggtgt gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac   2580

tcagaaacaa agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga   2640

ttaaggagag cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta   2700

atactactgc atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg   2760

ataatgaaag actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc   2820

tctttagtcg gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca   2880

ggaaaatcac aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct   2940

tcaaagcccc cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt   3000

ttatcaaatt cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg   3060

atcagagtga gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag   3120

ttccagccac agaaggtaaa aggacctctt ccctcctagg gtaaatcagc ttctgtgtca   3180

gggatgctgt gtggtgtcca tctgaacccc ctgcatacgc gtagctaatg tgatctcccc   3240

actttcacat aagatggtgg ccctgccttc agggaatgtg ggagccaggt gggagccttc   3300

ccggatattt aagctagaag attctacagg gagattctcc ttggatcaat atatgtctct   3360

cagtcaaaga tgtaaaagca cttttgcctt aaaaagaatg ttctgtttct aaatagagtc   3420

aacgttgtcc tcctcattgg aattcactat gagtcagaat cattagactg actttttttt   3480

ttccatagta atagtatttt gcagagtctc acagagctgc agatcttttg ttcatcttgc   3540

agagttaaca agtctgatcc tgttagtcca gatttcttaa atttggccaa gttataatag   3600

gagcagtagc ttgagacccg aagtcaggaa actttgacaa tggatttttt tttttaatcc   3660

agagacttgt actggaattt gccttaccct gtcagctcat ggacttaagg tttcatcccg   3720

ctttatgagt gcttctgaat ccaagtcatt gttacctgaa tttgcaaatt aagttgtgat   3780

attcgtgact gttaaattcc tgtaattaga ttaacctctt tgcttgcttg tttgttttct   3840

ctcctatttt agcttaaagt atcagtggtt gagaagagct tttcggacct gttactaccc   3900

caagctgtgt aatatacttg tataacagaa ataccttcta tacaaacctt tttttctact   3960

tttagataga aatgtctact ttttcagcag ttctgtgaat taaagagcag agtgactgtg   4020

ggtctggaat ggctggtgta cttgggaatg tactatcagg attttacagc aatgctggga   4080

aatgacaggg aaaatgacag gaatgaatct caccagattt tttatgtact cagcagagcc   4140

ttgagttacg gtgtttattt tccaatcaag tgaagatatc tcctacttct cctactggaa   4200

catctcagct tctgcagtga agaaaaattc ctgtgatagt tcagttcttt agtttttcta   4260

tttgaaaaaa aaaaatcatt taaatgatcc tttgttcacg gctctcctta atgactgagt   4320

gaacagttcc tatctgtata tttgactaaa ccttttccta agctatctct catggttcct   4380

atgttttttt atcataatta aaagcaaaac catctggatc acctaacagt cagaggtcag   4440

tatctcagcg tgtgaattat agaggaaata cagagagaac ctcttccact tttacttttc   4500

gtccaaataa aatgcatggt gtaccagaag ttgaagatcg ggttgaggat tggggctagc   4560

tcgatgacac taaggcccca acatcgcggg acctgctgtg gcgcggattc ttaggaacgc   4620

tgttctagcc ggccccctct ccaggggtcg ccgtggccgg cattatttcc tagttcttct   4680

tgtaaccctg aggtgccagc gcggggagtg aggaggggtc agggggctaa ggatgcaacc   4740

tctgacgttc tgcgccttcc taggagagtc ttacatgtgt tgagatttca caagcaatgc   4800

gagttgtaaa ataccagctc tacaagaagc taggctctgt gacggcatag ttttcagtag   4860

ctttatcaca atattcacaa tggagaatta tatgacatgg tagcagaaat aggccctttt   4920

atgtgttgct tctattttac ctcaaattgt agatataggg taatcaataa aatccatcca   4980

tgcctttcac acactaagt                                                4999


<210>  5261
<211>  968
<212>  PRT
<213>  Homo sapiens

<400>  5261

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu 
            580                 585                 590


Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg 
        595                 600                 605


Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys 
    610                 615                 620


Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys 
625                 630                 635                 640


Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly 
                645                 650                 655


Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn 
            660                 665                 670


Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn 
        675                 680                 685


Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu 
    690                 695                 700


Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu 
705                 710                 715                 720


Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys 
                725                 730                 735


Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu 
            740                 745                 750


Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile 
        755                 760                 765


Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile 
    770                 775                 780


Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser 
785                 790                 795                 800


Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr 
                805                 810                 815


Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro 
            820                 825                 830


Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu 
        835                 840                 845


Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile 
    850                 855                 860


Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn 
865                 870                 875                 880


Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys 
                885                 890                 895


Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser 
            900                 905                 910


Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val 
        915                 920                 925


Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile 
    930                 935                 940


Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Gly 
945                 950                 955                 960


Lys Arg Thr Ser Ser Leu Leu Gly 
                965


<210>  5262
<211>  5047
<212>  DNA
<213>  Homo sapiens

<400>  5262
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1980

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   2040

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2100

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2160

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2220

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2280

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2340

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2400

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2460

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2520

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2580

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2640

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2700

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2760

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2820

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2880

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2940

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   3000

tcaaattcac ggtcattaga ccatttccag gacttgtgat taataaccag ctggttgatc   3060

agagtgagtc agaaggcccc gtgatacaag aatcagctga accaagccag ttggaagttc   3120

cagccacaga agaaataaaa gagactgatg gaagctctca gatcaagcaa gaaccagacc   3180

ccacgtggta gacctcttcc ctcctagggt aaatcagctt ctgtgtcagg gatgctgtgt   3240

ggtgtccatc tgaaccccct gcatacgcgt agctaatgtg atctccccac tttcacataa   3300

gatggtggcc ctgccttcag ggaatgtggg agccaggtgg gagccttccc ggatatttaa   3360

gctagaagat tctacaggga gattctcctt ggatcaatat atgtctctca gtcaaagatg   3420

taaaagcact tttgccttaa aaagaatgtt ctgtttctaa atagagtcaa cgttgtcctc   3480

ctcattggaa ttcactatga gtcagaatca ttagactgac tttttttttt ccatagtaat   3540

agtattttgc agagtctcac agagctgcag atcttttgtt catcttgcag agttaacaag   3600

tctgatcctg ttagtccaga tttcttaaat ttggccaagt tataatagga gcagtagctt   3660

gagacccgaa gtcaggaaac tttgacaatg gatttttttt tttaatccag agacttgtac   3720

tggaatttgc cttaccctgt cagctcatgg acttaaggtt tcatcccgct ttatgagtgc   3780

ttctgaatcc aagtcattgt tacctgaatt tgcaaattaa gttgtgatat tcgtgactgt   3840

taaattcctg taattagatt aacctctttg cttgcttgtt tgttttctct cctattttag   3900

cttaaagtat cagtggttga gaagagcttt tcggacctgt tactacccca agctgtgtaa   3960

tatacttgta taacagaaat accttctata caaacctttt tttctacttt tagatagaaa   4020

tgtctacttt ttcagcagtt ctgtgaatta aagagcagag tgactgtggg tctggaatgg   4080

ctggtgtact tgggaatgta ctatcaggat tttacagcaa tgctgggaaa tgacagggaa   4140

aatgacagga atgaatctca ccagattttt tatgtactca gcagagcctt gagttacggt   4200

gtttattttc caatcaagtg aagatatctc ctacttctcc tactggaaca tctcagcttc   4260

tgcagtgaag aaaaattcct gtgatagttc agttctttag tttttctatt tgaaaaaaaa   4320

aaatcattta aatgatcctt tgttcacggc tctccttaat gactgagtga acagttccta   4380

tctgtatatt tgactaaacc ttttcctaag ctatctctca tggttcctat gtttttttat   4440

cataattaaa agcaaaacca tctggatcac ctaacagtca gaggtcagta tctcagcgtg   4500

tgaattatag aggaaataca gagagaacct cttccacttt tacttttcgt ccaaataaaa   4560

tgcatggtgt accagaagtt gaagatcggg ttgaggattg gggctagctc gatgacacta   4620

aggccccaac atcgcgggac ctgctgtggc gcggattctt aggaacgctg ttctagccgg   4680

ccccctctcc aggggtcgcc gtggccggca ttatttccta gttcttcttg taaccctgag   4740

gtgccagcgc ggggagtgag gaggggtcag ggggctaagg atgcaacctc tgacgttctg   4800

cgccttccta ggagagtctt acatgtgttg agatttcaca agcaatgcga gttgtaaaat   4860

accagctcta caagaagcta ggctctgtga cggcatagtt ttcagtagct ttatcacaat   4920

attcacaatg gagaattata tgacatggta gcagaaatag gcccttttat gtgttgcttc   4980

tattttacct caaattgtag atatagggta atcaataaaa tccatccatg cctttcacac   5040

actaagt                                                             5047


<210>  5263
<211>  977
<212>  PRT
<213>  Homo sapiens

<400>  5263

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr 
                565                 570                 575


Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro 
            580                 585                 590


Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu 
        595                 600                 605


Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys 
    610                 615                 620


Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile 
625                 630                 635                 640


Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser 
                645                 650                 655


Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn 
            660                 665                 670


Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly 
        675                 680                 685


Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala 
    690                 695                 700


Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe 
705                 710                 715                 720


Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val 
                725                 730                 735


Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly 
            740                 745                 750


Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro 
        755                 760                 765


Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile 
    770                 775                 780


Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser 
785                 790                 795                 800


Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr 
                805                 810                 815


Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp 
            820                 825                 830


Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg 
        835                 840                 845


Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly 
    850                 855                 860


Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro 
865                 870                 875                 880


Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala 
                885                 890                 895


Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala 
            900                 905                 910


Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile 
        915                 920                 925


Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln 
    930                 935                 940


Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu Ile 
945                 950                 955                 960


Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro Thr 
                965                 970                 975


Trp 



<210>  5264
<211>  3671
<212>  DNA
<213>  Homo sapiens

<400>  5264
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agctcaagct cttggactca ccgaggcagt aaaagtacca tatcctgtgt   1860

ttgaatcaaa cccggagttc ttgtatgtgg aaggcttgcc agaggggatt cccttccgaa   1920

gccctacctg gtttggaatt ccacgacttg aaaggatcgt ccgcgggagt aataaaatca   1980

agttcgttgt taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta   2040

aaataaacac taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa   2100

aggttcctga aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag   2160

ctgttcgaac cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag   2220

agttttcctt tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc   2280

tcttcaatga gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg   2340

cgttatttga gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat   2400

tccgaagacc atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca   2460

aaattaagtt catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct   2520

cctctaagag ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag   2580

gtgttgaaga ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct   2640

cgaaagttga aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat   2700

ttggtgaagc tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta   2760

accctggctg tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct   2820

acctggaaat cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg   2880

tcattagacc atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag   2940

aaggccccgt gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag   3000

aaataaaaga gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga   3060

cctcttccct cctaggcaaa accatctgga tcacctaaca gtcagaggtc agtatctcag   3120

cgtgtgaatt atagaggaaa tacagagaga acctcttcca cttttacttt tcgtccaaat   3180

aaaatgcatg gtgtaccaga agttgaagat cgggttgagg attggggcta gctcgatgac   3240

actaaggccc caacatcgcg ggacctgctg tggcgcggat tcttaggaac gctgttctag   3300

ccggccccct ctccaggggt cgccgtggcc ggcattattt cctagttctt cttgtaaccc   3360

tgaggtgcca gcgcggggag tgaggagggg tcagggggct aaggatgcaa cctctgacgt   3420

tctgcgcctt cctaggagag tcttacatgt gttgagattt cacaagcaat gcgagttgta   3480

aaataccagc tctacaagaa gctaggctct gtgacggcat agttttcagt agctttatca   3540

caatattcac aatggagaat tatatgacat ggtagcagaa ataggccctt ttatgtgttg   3600

cttctatttt acctcaaatt gtagatatag ggtaatcaat aaaatccatc catgcctttc   3660

acacactaag t                                                        3671


<210>  5265
<211>  933
<212>  PRT
<213>  Homo sapiens

<400>  5265

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly Leu Thr Glu Ala Val 
        515                 520                 525


Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val 
    530                 535                 540


Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly 
545                 550                 555                 560


Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe 
                565                 570                 575


Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met 
            580                 585                 590


Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg 
        595                 600                 605


Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu 
    610                 615                 620


Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr 
625                 630                 635                 640


Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe 
                645                 650                 655


Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val 
            660                 665                 670


Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln 
        675                 680                 685


Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe 
    690                 695                 700


Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr 
705                 710                 715                 720


Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile 
                725                 730                 735


Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu 
            740                 745                 750


Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn 
        755                 760                 765


Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val 
    770                 775                 780


Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala 
785                 790                 795                 800


Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly 
                805                 810                 815


Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile 
            820                 825                 830


Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val 
        835                 840                 845


Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile 
    850                 855                 860


Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro 
865                 870                 875                 880


Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly 
                885                 890                 895


Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala 
            900                 905                 910


Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln Glu 
        915                 920                 925


Pro Asp Pro Thr Trp 
    930


<210>  5266
<211>  3736
<212>  DNA
<213>  Homo sapiens

<400>  5266
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1980

catatcctgt gtttgaatca aacccggagt tcttgaaagg atcgtccgcg ggagtaataa   2040

aatcaagttc gttgttaaaa aacctgaact agttatttcc tacttgcctc ctgggatggc   2100

tagtaaaata aacactaaag ctttgcagtc ccccaaaaga ccacgaagtc ctgggagtaa   2160

ttcaaaggtt cctgaaattg aggtcaccgt ggaaggccct aataacaaca atcctcaaac   2220

ctcagctgtt cgaaccccga cccagactaa cggttctaac gttcccttca agccacgagg   2280

gagagagttt tcctttgagg cctggaatgc caaaatcacg gacctaaaac agaaagttga   2340

aaatctcttc aatgagaaat gtggggaagc tcttggcctt aaacaagctg tgaaggtgcc   2400

gttcgcgtta tttgagtctt tcccggaaga cttttatgtg gaaggcttac ctgagggtgt   2460

gccattccga agaccatcga cttttggcat tccgaggctg gagaagatac tcagaaacaa   2520

agccaaaatt aagttcatca ttaaaaagcc cgaaatgttt gagacggcga ttaaggagag   2580

cacctcctct aagagccctc ccagaaaaat aaattcatca cccaatgtta atactactgc   2640

atcaggtgtt gaagacctta acatcattca ggtgacaatt ccagatgatg ataatgaaag   2700

actctcgaaa gttgaaaaag ctagacagct aagagaacaa gtgaatgacc tctttagtcg   2760

gaaatttggt gaagctattg gtatgggttt tcctgtgaaa gttccctaca ggaaaatcac   2820

aattaaccct ggctgtgtgg tggttgatgg catgcccccg ggggtgtcct tcaaagcccc   2880

cagctacctg gaaatcagct ccatgagaag gatcttagac tctgccgagt ttatcaaatt   2940

cacggtcatt agaccatttc caggacttgt gattaataac cagctggttg atcagagtga   3000

gtcagaaggc cccgtgatac aagaatcagc tgaaccaagc cagttggaag ttccagccac   3060

agaagaaata aaagagactg atggaagctc tcagatcaag caagaaccag accccacgtg   3120

gtagacctct tccctcctag gcaaaaccat ctggatcacc taacagtcag aggtcagtat   3180

ctcagcgtgt gaattataga ggaaatacag agagaacctc ttccactttt acttttcgtc   3240

caaataaaat gcatggtgta ccagaagttg aagatcgggt tgaggattgg ggctagctcg   3300

atgacactaa ggccccaaca tcgcgggacc tgctgtggcg cggattctta ggaacgctgt   3360

tctagccggc cccctctcca ggggtcgccg tggccggcat tatttcctag ttcttcttgt   3420

aaccctgagg tgccagcgcg gggagtgagg aggggtcagg gggctaagga tgcaacctct   3480

gacgttctgc gccttcctag gagagtctta catgtgttga gatttcacaa gcaatgcgag   3540

ttgtaaaata ccagctctac aagaagctag gctctgtgac ggcatagttt tcagtagctt   3600

tatcacaata ttcacaatgg agaattatat gacatggtag cagaaatagg cccttttatg   3660

tgttgcttct attttacctc aaattgtaga tatagggtaa tcaataaaat ccatccatgc   3720

ctttcacaca ctaagt                                                   3736


<210>  5267
<211>  604
<212>  PRT
<213>  Homo sapiens

<400>  5267

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr 
                565                 570                 575


Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala Gly 
            580                 585                 590


Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600


<210>  5268
<211>  7845
<212>  DNA
<213>  Homo sapiens

<400>  5268
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggaagccac cattcttcag    960

agggcaatga aggcacagaa atggaagtac cagcagaaga ttctactcaa catgtccctt   1020

cagaaacaag tgaggaccct gaagttgagg tgactattga agatgatgat tattctccac   1080

cgtctaagag accaaaggcc aatgagctac cgcagccacc agtcccggaa cccgccaatg   1140

ctgggaagcg gaaagtgagg gagttcaact tcgagaaatg gaatgctcgc atcactgatc   1200

tacgtaaaca agttgaagaa ttgtttgaaa ggaaatatgc tcaagccata aaagccaaag   1260

gtccggtgac gatcccgtac cctcttttcc agtctcatgt tgaagatctt tatgtagaag   1320

gacttcctga aggaattcct tttagaaggc catctactta cggaattcct cgcctggaga   1380

ggatattact tgcaaaggaa aggattcgtt ttgtgattaa gaaacatgag cttctgaatt   1440

caacacgtga agatttacag cttgataagc cagcttcagg agtaaaggaa gaatggtatg   1500

ccagaatcac taaattaaga aagatggtgg atcagctttt ctgcaaaaaa tttgcggaag   1560

ccttggggag cactgaagcc aaggctgtac cgtaccaaaa atttgaggca cacccgaatg   1620

atctgtacgt ggaaggactg ccagaaaaca ttcctttccg aagtccctca tggtatggaa   1680

tcccaaggct ggaaaaaatc attcaagtgg gcaatcgaat taaatttgtt attaaaagac   1740

cagaacttct gactcacagt accactgaag ttactcagcc aagaacgaat acaccagtca   1800

aagaagattg gaatgtcaga attaccaagc tacggaagca agtggaagag atttttaatt   1860

tgaaatttgc ttagatttgt tgacagcggt ttcctggagt gctgtcttga gaacgattct   1920

gaggaggctc agcaagaaag agtgtttcag ttgattgggt gtgtctgtca tggagaagga   1980

actcaagctc ttggactcac cgaggcagta aaagtaccat atcctgtgtt tgaatcaaac   2040

ccggagttct tgtatgtgga aggcttgcca gaggggattc ccttccgaag ccctacctgg   2100

tttggaattc cacgacttga aaggatcgtc cgcgggagta ataaaatcaa gttcgttgtt   2160

aaaaaacctg aactagttat ttcctacttg cctcctggga tggctagtaa aataaacact   2220

aaagctttgc agtcccccaa aagaccacga agtcctggga gtaattcaaa ggttcctgaa   2280

attgaggtca ccgtggaagg ccctaataac aacaatcctc aaacctcagc tgttcgaacc   2340

ccgacccaga ctaacggttc taacgttccc ttcaagccac gagggagaga gttttccttt   2400

gaggcctgga atgccaaaat cacggaccta aaacagaaag ttgaaaatct cttcaatgag   2460

aaatgtgggg aagctcttgg ccttaaacaa gctgtgaagg tgccgttcgc gttatttgag   2520

tctttcccgg aagactttta tgtggaaggc ttacctgagg gtgtgccatt ccgaagacca   2580

tcgacttttg gcattccgag gctggagaag atactcagaa acaaagccaa aattaagttc   2640

atcattaaaa agcccgaaat gtttgagacg gcgattaagg agagcacctc ctctaagagc   2700

cctcccagaa aaataaattc atcacccaat gttaatacta ctgcatcagg tgttgaagac   2760

cttaacatca ttcaggtgac aattccagat gatgataatg aaagactctc gaaagttgaa   2820

aaagctagac agctaagaga acaagtgaat gacctcttta gtcggaaatt tggtgaagct   2880

attggtatgg gttttcctgt gaaagttccc tacaggaaaa tcacaattaa ccctggctgt   2940

gtggtggttg atggcatgcc cccgggggtg tccttcaaag cccccagcta cctggaaatc   3000

agctccatga gaaggatctt agactctgcc gagtttatca aattcacggt cattaggtaa   3060

gtgagagttt cctgcttagt cacaggagcg aatctggagc tcatgaggct gactcttcta   3120

aaatgcagcc acaggtagtc atcgaatccg gcttcctatg ctgtgcaatc aacaaatcaa   3180

aataacttgt gtcatcatta gaatgtcaga tgtgcttcta cgaactaagc tgactctttt   3240

aattctttgg caaagggttg gcaaactagg actgtttgcc aaattcaggc tgcctcctat   3300

ttttagagtc ttcctgaaac acagctacac ccgtattatc catggctgct ttcctgtcac   3360

agtgagtaag tagctgggac tgagaaggca tggcctccaa agtctaaaat atttactctc   3420

tagcactttg tagaaaaacc ttagctaggc acagtggcta acgcctgtaa tcccagcatt   3480

ttgggaggcc aaggcaggca gatcacctga ggtcaggagt tccagaccag cctggccaac   3540

atggtgaaat cccatctcta caaaaataaa acagttagct gggcatgatg gcgggtgcct   3600

gtaatcccag ctactcggga ggctgaggca ggatagtcgc ttgaacccag gaggtggagg   3660

ttgcaatgag ccaagatcat gccactgcac tccagcctgg acgacagagt gagactccat   3720

cacaagaaaa aaagaacttt gtcaacctct gtcttagggc gccttgtcac aggcttcggg   3780

tcagacggat tcaaccttgc atcagccatt tgttagccag gtcactctgt tctttgtctg   3840

taaatgagat tgatcgttgt tcccactgag agtgtcagct ccttcccgta gagcaggcat   3900

gatgattgta ctcacctctg acaccattgt gagtgccaca ttccttccca cgtccttgtc   3960

actgtaagag atgcccacct gagcaccaac cccaggttat cttccccttt gtcttccagc   4020

cccccagaaa cagctacgac tcaacctacc caatcatttc atcatcagat tgccactgtc   4080

tctagttcag gtctcttggg actggcactc agaaatctca taataaatcc tcttgaggct   4140

tctcatacac tcgtcttctt ccaatcttct ttccctcaaa atctcatatt ttggttccac   4200

ttcacccacc gtcattctcc atatcactcc caggagttag gcaaaaagcc ccttccgttc   4260

ttccgtatgt taaacttaga atcactctgt tccctgctct gcgtttctat tttttgtttt   4320

tcctccattt actagtagct taacactttc taacagtgtt cttattattg atacgtatct   4380

atctcttcca taagcttata aggtcacgga taatacttct cattgtagta cgtaaatgac   4440

gtgggctaga tatgagttga ataaacagtt atacctgtaa attcttacag agtgaaaata   4500

aattgttata ctttacaatt tgtttctctc tttagaccat ttccaggact tgtgattaat   4560

aaccgtgagt attttgtgaa gtgttttgtt tttgtttttt cctggggtct gacgtgtgtg   4620

cgtgtgagtg tgtatacatg cttaacgtat atcacgttac ttcacctatg tcagtaacca   4680

ggccaaatac ttgttttagc cctcagtaaa aacaccaggc acttcctagt tgtaaaatta   4740

ttcaagcttc ttaacttcct atcctcgatg cacttaatca taaaatggta ataatagcac   4800

cgattttggg ggagtcgttc cagtagatgg aaagcatctg gaacaggtgt cagcaagctc   4860

ctgccgacgt gtatgcataa agttttattg aaaccaccat cgtgtccatt tgtttatggc   4920

agaactgaga gatggcagca gcaagtgtgt gcctgcaaaa cctaaaatat ttactaattg   4980

gctctgcaag aaaagagttt gcatccccct aacctagaac agtgtctagc ctctagtatg   5040

tgtttagcct acagtatgtg ctcagcgaat acaatctata tttattactg cttttatgac   5100

tgttataatt actgtgcttg gatttcgtta caaagtaagt cacaatgtgc ctgcttctgt   5160

tagtatttca gcacagtgcc tggcacacat ggggctctca aatattgctg agcgagtgaa   5220

caaatgtcct ttcaattcct taacgttgat gtcattttca atagtatttt gagccaaact   5280

taattttgcg agtgtgtttt gttttcttaa ctttattatt aaaaatgtat aaaagtgagg   5340

ccaggcgtgg tggctcacgc ctgtaatccc agcagtttgg gaggctgagg caggcggatc   5400

agttgaggtt gggagttgga gaccagcccg tccaacatgg tgaaagcctg tctctactaa   5460

aaatacaaaa atcagctggg tgtggtggcg cgtgcctgta atcccagcta ctcaggaggc   5520

tgaggcagga gagttgcttg aatcctagag gtggaggttg cagtgagctg agatcgtgcc   5580

attgcactcc agcctgggca acaagagcaa aactctgtcc caataaataa ataaataaaa   5640

tgttctcttt tgttcctgtt cttgtgcggt agtgtggtat agagttttat ggtaattact   5700

gtgaattagt gattctgagg gacatatcag aactctgagg tttgtttcct tctcatcttg   5760

agggaaacag caaatgtatg ttaaaatgct tttccaaggg aacaacacat ccttacatta   5820

tttaaaccaa tctgcttcat tttcagagct ggttgatcag agtgagtcag aaggccccgt   5880

gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag aaataaaaga   5940

gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga cctcttccct   6000

cctagggtaa atcagcttct gtgtcaggga tgctgtgtgg tgtccatctg aaccccctgc   6060

atacgcgtag ctaatgtgat ctccccactt tcacataaga tggtggccct gccttcaggg   6120

aatgtgggag ccaggtggga gccttcccgg atatttaagc tagaagattc tacagggaga   6180

ttctccttgg atcaatatat gtctctcagt caaagatgta aaagcacttt tgccttaaaa   6240

agaatgttct gtttctaaat agagtcaacg ttgtcctcct cattggaatt cactatgagt   6300

cagaatcatt agactgactt ttttttttcc atagtaatag tattttgcag agtctcacag   6360

agctgcagat cttttgttca tcttgcagag ttaacaagtc tgatcctgtt agtccagatt   6420

tcttaaattt ggccaagtta taataggagc agtagcttga gacccgaagt caggaaactt   6480

tgacaatgga tttttttttt taatccagag acttgtactg gaatttgcct taccctgtca   6540

gctcatggac ttaaggtttc atcccgcttt atgagtgctt ctgaatccaa gtcattgtta   6600

cctgaatttg caaattaagt tgtgatattc gtgactgtta aattcctgta attagattaa   6660

cctctttgct tgcttgtttg ttttctctcc tattttagct taaagtatca gtggttgaga   6720

agagcttttc ggacctgtta ctaccccaag ctgtgtaata tacttgtata acagaaatac   6780

cttctataca aacctttttt tctactttta gatagaaatg tctacttttt cagcagttct   6840

gtgaattaaa gagcagagtg actgtgggtc tggaatggct ggtgtacttg ggaatgtact   6900

atcaggattt tacagcaatg ctgggaaatg acagggaaaa tgacaggaat gaatctcacc   6960

agatttttta tgtactcagc agagccttga gttacggtgt ttattttcca atcaagtgaa   7020

gatatctcct acttctccta ctggaacatc tcagcttctg cagtgaagaa aaattcctgt   7080

gatagttcag ttctttagtt tttctatttg aaaaaaaaaa atcatttaaa tgatcctttg   7140

ttcacggctc tccttaatga ctgagtgaac agttcctatc tgtatatttg actaaacctt   7200

ttcctaagct atctctcatg gttcctatgt ttttttatca taattaaaag caaaaccatc   7260

tggatcacct aacagtcaga ggtcagtatc tcagcgtgtg aattatagag gaaatacaga   7320

gagaacctct tccactttta cttttcgtcc aaataaaatg catggtgtac cagaagttga   7380

agatcgggtt gaggattggg gctagctcga tgacactaag gccccaacat cgcgggacct   7440

gctgtggcgc ggattcttag gaacgctgtt ctagccggcc ccctctccag gggtcgccgt   7500

ggccggcatt atttcctagt tcttcttgta accctgaggt gccagcgcgg ggagtgagga   7560

ggggtcaggg ggctaaggat gcaacctctg acgttctgcg ccttcctagg agagtcttac   7620

atgtgttgag atttcacaag caatgcgagt tgtaaaatac cagctctaca agaagctagg   7680

ctctgtgacg gcatagtttt cagtagcttt atcacaatat tcacaatgga gaattatatg   7740

acatggtagc agaaataggc ccttttatgt gttgcttcta ttttacctca aattgtagat   7800

atagggtaat caataaaatc catccatgcc tttcacacac taagt                   7845


<210>  5269
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  5269

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr 
225                 230                 235                 240


Glu Met Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu 
                245                 250                 255


Thr Ser Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr 
            260                 265                 270


Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro 
        275                 280                 285


Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn 
    290                 295                 300


Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu 
305                 310                 315                 320


Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro 
                325                 330                 335


Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr 
            340                 345                 350


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr 
        355                 360                 365


Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg 
    370                 375                 380


Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu 
385                 390                 395                 400


Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg 
                405                 410                 415


Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe 
            420                 425                 430


Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys 
        435                 440                 445


Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn 
    450                 455                 460


Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys 
465                 470                 475                 480


Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu 
                485                 490                 495


Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr 
            500                 505                 510


Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln 
        515                 520                 525


Val Glu Glu Ile Phe Asn Leu Lys Phe Ala 
    530                 535


<210>  5270
<211>  7116
<212>  DNA
<213>  Homo sapiens

<400>  5270
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1980

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   2040

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2100

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2160

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2220

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2280

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2340

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2400

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2460

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2520

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2580

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2640

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2700

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2760

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2820

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2880

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2940

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   3000

tcaaattcac ggtcattagg taagtgagag tttcctgctt agtcacagga gcgaatctgg   3060

agctcatgag gctgactctt ctaaaatgca gccacaggta gtcatcgaat ccggcttcct   3120

atgctgtgca atcaacaaat caaaataact tgtgtcatca ttagaatgtc agatgtgctt   3180

ctacgaacta agctgactct tttaattctt tggcaaaggg ttggcaaact aggactgttt   3240

gccaaattca ggctgcctcc tatttttaga gtcttcctga aacacagcta cacccgtatt   3300

atccatggct gctttcctgt cacagtgagt aagtagctgg gactgagaag gcatggcctc   3360

caaagtctaa aatatttact ctctagcact ttgtagaaaa accttagcta ggcacagtgg   3420

ctaacgcctg taatcccagc attttgggag gccaaggcag gcagatcacc tgaggtcagg   3480

agttccagac cagcctggcc aacatggtga aatcccatct ctacaaaaat aaaacagtta   3540

gctgggcatg atggcgggtg cctgtaatcc cagctactcg ggaggctgag gcaggatagt   3600

cgcttgaacc caggaggtgg aggttgcaat gagccaagat catgccactg cactccagcc   3660

tggacgacag agtgagactc catcacaaga aaaaaagaac tttgtcaacc tctgtcttag   3720

ggcgccttgt cacaggcttc gggtcagacg gattcaacct tgcatcagcc atttgttagc   3780

caggtcactc tgttctttgt ctgtaaatga gattgatcgt tgttcccact gagagtgtca   3840

gctccttccc gtagagcagg catgatgatt gtactcacct ctgacaccat tgtgagtgcc   3900

acattccttc ccacgtcctt gtcactgtaa gagatgccca cctgagcacc aaccccaggt   3960

tatcttcccc tttgtcttcc agccccccag aaacagctac gactcaacct acccaatcat   4020

ttcatcatca gattgccact gtctctagtt caggtctctt gggactggca ctcagaaatc   4080

tcataataaa tcctcttgag gcttctcata cactcgtctt cttccaatct tctttccctc   4140

aaaatctcat attttggttc cacttcaccc accgtcattc tccatatcac tcccaggagt   4200

taggcaaaaa gccccttccg ttcttccgta tgttaaactt agaatcactc tgttccctgc   4260

tctgcgtttc tattttttgt ttttcctcca tttactagta gcttaacact ttctaacagt   4320

gttcttatta ttgatacgta tctatctctt ccataagctt ataaggtcac ggataatact   4380

tctcattgta gtacgtaaat gacgtgggct agatatgagt tgaataaaca gttatacctg   4440

taaattctta cagagtgaaa ataaattgtt atactttaca atttgtttct ctctttagac   4500

catttccagg acttgtgatt aataaccgtg agtattttgt gaagtgtttt gtttttgttt   4560

tttcctgggg tctgacgtgt gtgcgtgtga gtgtgtatac atgcttaacg tatatcacgt   4620

tacttcacct atgtcagtaa ccaggccaaa tacttgtttt agccctcagt aaaaacacca   4680

ggcacttcct agttgtaaaa ttattcaagc ttcttaactt cctatcctcg atgcacttaa   4740

tcataaaatg gtaataatag caccgatttt gggggagtcg ttccagtaga tggaaagcat   4800

ctggaacagg tgtcagcaag ctcctgccga cgtgtatgca taaagtttta ttgaaaccac   4860

catcgtgtcc atttgtttat ggcagaactg agagatggca gcagcaagtg tgtgcctgca   4920

aaacctaaaa tatttactaa ttggctctgc aagaaaagag tttgcatccc cctaacctag   4980

aacagtgtct agcctctagt atgtgtttag cctacagtat gtgctcagcg aatacaatct   5040

atatttatta ctgcttttat gactgttata attactgtgc ttggatttcg ttacaaagta   5100

agtcacaatg tgcctgcttc tgttagtatt tcagcacagt gcctggcaca catggggctc   5160

tcaaatattg ctgagcgagt gaacaaatgt cctttcaatt ccttaacgtt gatgtcattt   5220

tcaatagtat tttgagccaa acttaatttt gcgagtgtgt tttgttttct taactttatt   5280

attaaaaatg tataaaagtg aggccaggcg tggtggctca cgcctgtaat cccagcagtt   5340

tgggaggctg aggcaggcgg atcagttgag gttgggagtt ggagaccagc ccgtccaaca   5400

tggtgaaagc ctgtctctac taaaaataca aaaatcagct gggtgtggtg gcgcgtgcct   5460

gtaatcccag ctactcagga ggctgaggca ggagagttgc ttgaatccta gaggtggagg   5520

ttgcagtgag ctgagatcgt gccattgcac tccagcctgg gcaacaagag caaaactctg   5580

tcccaataaa taaataaata aaatgttctc ttttgttcct gttcttgtgc ggtagtgtgg   5640

tatagagttt tatggtaatt actgtgaatt agtgattctg agggacatat cagaactctg   5700

aggtttgttt ccttctcatc ttgagggaaa cagcaaatgt atgttaaaat gcttttccaa   5760

gggaacaaca catccttaca ttatttaaac caatctgctt cattttcaga gctggttgat   5820

cagagtgagt cagaaggccc cgtgatacaa gaatcagctg aaccaagcca gttggaagtt   5880

ccagccacag aagaaataaa agagactgat ggaagctctc agatcaagca agaaccagac   5940

cccacgtggt agacctcttc cctcctaggc ttaaagtatc agtggttgag aagagctttt   6000

cggacctgtt actaccccaa gctgtgtaat atacttgtat aacagaaata ccttctatac   6060

aaaccttttt ttctactttt agatagaaat gtctactttt tcagcagttc tgtgaattaa   6120

agagcagagt gactgtgggt ctggaatggc tggtgtactt gggaatgtac tatcaggatt   6180

ttacagcaat gctgggaaat gacagggaaa atgacaggaa tgaatctcac cagatttttt   6240

atgtactcag cagagccttg agttacggtg tttattttcc aatcaagtga agatatctcc   6300

tacttctcct actggaacat ctcagcttct gcagtgaaga aaaattcctg tgatagttca   6360

gttctttagt ttttctattt gaaaaaaaaa aatcatttaa atgatccttt gttcacggct   6420

ctccttaatg actgagtgaa cagttcctat ctgtatattt gactaaacct tttcctaagc   6480

tatctctcat ggttcctatg tttttttatc ataattaaaa gcaaaaccat ctggatcacc   6540

taacagtcag aggtcagtat ctcagcgtgt gaattataga ggaaatacag agagaacctc   6600

ttccactttt acttttcgtc caaataaaat gcatggtgta ccagaagttg aagatcgggt   6660

tgaggattgg ggctagctcg atgacactaa ggccccaaca tcgcgggacc tgctgtggcg   6720

cggattctta ggaacgctgt tctagccggc cccctctcca ggggtcgccg tggccggcat   6780

tatttcctag ttcttcttgt aaccctgagg tgccagcgcg gggagtgagg aggggtcagg   6840

gggctaagga tgcaacctct gacgttctgc gccttcctag gagagtctta catgtgttga   6900

gatttcacaa gcaatgcgag ttgtaaaata ccagctctac aagaagctag gctctgtgac   6960

ggcatagttt tcagtagctt tatcacaata ttcacaatgg agaattatat gacatggtag   7020

cagaaatagg cccttttatg tgttgcttct attttacctc aaattgtaga tatagggtaa   7080

tcaataaaat ccatccatgc ctttcacaca ctaagt                             7116


<210>  5271
<211>  921
<212>  PRT
<213>  Homo sapiens

<400>  5271

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr 
                565                 570                 575


Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro 
            580                 585                 590


Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu 
        595                 600                 605


Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys 
    610                 615                 620


Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile 
625                 630                 635                 640


Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser 
                645                 650                 655


Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn 
            660                 665                 670


Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly 
        675                 680                 685


Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala 
    690                 695                 700


Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe 
705                 710                 715                 720


Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val 
                725                 730                 735


Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly 
            740                 745                 750


Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro 
        755                 760                 765


Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile 
    770                 775                 780


Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser 
785                 790                 795                 800


Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr 
                805                 810                 815


Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp 
            820                 825                 830


Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg 
        835                 840                 845


Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly 
    850                 855                 860


Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro 
865                 870                 875                 880


Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala 
                885                 890                 895


Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala 
            900                 905                 910


Glu Phe Ile Lys Phe Thr Val Ile Arg 
        915                 920


<210>  5272
<211>  4062
<212>  DNA
<213>  Homo sapiens

<400>  5272
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagctcaa gctcttggac tcaccgaggc agtaaaagta ccatatcctg   1980

tgtttgaatc aaacccggag ttcttgtatg tggaaggctt gccagagggg attcccttcc   2040

gaagccctac ctggtttgga attccacgac ttgaaaggat cgtccgcggg agtaataaaa   2100

tcaagttcgt tgttaaaaaa cctgaactag ttatttccta cttgcctcct gggatggcta   2160

gtaaaataaa cactaaagct ttgcagtccc ccaaaagacc acgaagtcct gggagtaatt   2220

caaaggttcc tgaaattgag gtcaccgtgg aaggccctaa taacaacaat cctcaaacct   2280

cagctgttcg aaccccgacc cagactaacg gttctaacgt tcccttcaag ccacgaggga   2340

gagagttttc ctttgaggcc tggaatgcca aaatcacgga cctaaaacag aaagttgaaa   2400

atctcttcaa tgagaaatgt ggggaagctc ttggccttaa acaagctgtg aaggtgccgt   2460

tcgcgttatt tgagtctttc ccggaagact tttatgtgga aggcttacct gagggtgtgc   2520

cattccgaag accatcgact tttggcattc cgaggctgga gaagatactc agaaacaaag   2580

ccaaaattaa gttcatcatt aaaaagcccg aaatgtttga gacggcgatt aaggagagca   2640

cctcctctaa gagccctccc agaaaaataa attcatcacc caatgttaat actactgcat   2700

caggtgttga agaccttaac atcattcagg tgacaattcc agatgatgat aatgaaagac   2760

tctcgaaagt tgaaaaagct agacagctaa gagaacaagt gaatgacctc tttagtcgga   2820

aatttggtga agctattggt atgggttttc ctgtgaaagt tccctacagg aaaatcacaa   2880

ttaaccctgg ctgtgtggtg gttgatggca tgcccccggg ggtgtccttc aaagccccca   2940

gctacctgga aatcagctcc atgagaagga tcttagactc tgccgagttt atcaaattca   3000

cggtcattag accatttcca ggacttgtga ttaataacca gctggttgat cagagtgagt   3060

cagaaggccc cgtgatacaa gaatcagctg aaccaagcca gttggaagtt ccagccacag   3120

aagaaataaa agagactgat ggaagctctc agatcaagca agaaccagac cccacgtggt   3180

agacctcttc cctcctagga gccttgagtt acggtgttta ttttccaatc aagtgaagat   3240

atctcctact tctcctactg gaacatctca gcttctgcag tgaagaaaaa ttcctgtgat   3300

agttcagttc tttagttttt ctatttgaaa aaaaaaaatc atttaaatga tcctttgttc   3360

acggctctcc ttaatgactg agtgaacagt tcctatctgt atatttgact aaaccttttc   3420

ctaagctatc tctcatggtt cctatgtttt tttatcataa ttaaaagcaa aaccatctgg   3480

atcacctaac agtcagaggt cagtatctca gcgtgtgaat tatagaggaa atacagagag   3540

aacctcttcc acttttactt ttcgtccaaa taaaatgcat ggtgtaccag aagttgaaga   3600

tcgggttgag gattggggct agctcgatga cactaaggcc ccaacatcgc gggacctgct   3660

gtggcgcgga ttcttaggaa cgctgttcta gccggccccc tctccagggg tcgccgtggc   3720

cggcattatt tcctagttct tcttgtaacc ctgaggtgcc agcgcgggga gtgaggaggg   3780

gtcagggggc taaggatgca acctctgacg ttctgcgcct tcctaggaga gtcttacatg   3840

tgttgagatt tcacaagcaa tgcgagttgt aaaataccag ctctacaaga agctaggctc   3900

tgtgacggca tagttttcag tagctttatc acaatattca caatggagaa ttatatgaca   3960

tggtagcaga aataggccct tttatgtgtt gcttctattt tacctcaaat tgtagatata   4020

gggtaatcaa taaaatccat ccatgccttt cacacactaa gt                      4062


<210>  5273
<211>  974
<212>  PRT
<213>  Homo sapiens

<400>  5273

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Ala 
545                 550                 555                 560


Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe 
                565                 570                 575


Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile 
            580                 585                 590


Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile 
        595                 600                 605


Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu 
    610                 615                 620


Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys 
625                 630                 635                 640


Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys 
                645                 650                 655


Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro 
            660                 665                 670


Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val 
        675                 680                 685


Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala 
    690                 695                 700


Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys 
705                 710                 715                 720


Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala 
                725                 730                 735


Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu 
            740                 745                 750


Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu 
        755                 760                 765


Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro 
    770                 775                 780


Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro 
785                 790                 795                 800


Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly 
                805                 810                 815


Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn 
            820                 825                 830


Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val 
        835                 840                 845


Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe 
    850                 855                 860


Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val 
865                 870                 875                 880


Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr 
                885                 890                 895


Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile 
            900                 905                 910


Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln 
        915                 920                 925


Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala 
    930                 935                 940


Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr 
945                 950                 955                 960


Asp Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro Thr Trp 
                965                 970


<210>  5274
<211>  4467
<212>  DNA
<213>  Homo sapiens

<400>  5274
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1920

aagagatttt taatttgaaa tttgcttaga tttgttgaca gcggtttcct ggagtgctgt   1980

cttgagaacg attctgagga ggctcagcaa gaaagagtgt ttcagttgat tgggtgtgtc   2040

tgtcatggag aaggaactca agctcttgga ctcaccgagg cagtaaaagt accatatcct   2100

gtgtttgaat caaacccgga gttcttgtat gtggaaggct tgccagaggg gattcccttc   2160

cgaagcccta cctggtttgg aattccacga cttgaaagga tcgtccgcgg gagtaataaa   2220

atcaagttcg ttgttaaaaa acctgaacta gttatttcct acttgcctcc tgggatggct   2280

agtaaaataa acactaaagc tttgcagtcc cccaaaagac cacgaagtcc tgggagtaat   2340

tcaaaggttc ctgaaattga ggtcaccgtg gaaggcccta ataacaacaa tcctcaaacc   2400

tcagctgttc gaaccccgac ccagactaac ggttctaacg ttcccttcaa gccacgaggg   2460

agagagtttt cctttgaggc ctggaatgcc aaaatcacgg acctaaaaca gaaagttgaa   2520

aatctcttca atgagaaatg tggggaagct cttggcctta aacaagctgt gaaggtgccg   2580

ttcgcgttat ttgagtcttt cccggaagac ttttatgtgg aaggcttacc tgagggtgtg   2640

ccattccgaa gaccatcgac ttttggcatt ccgaggctgg agaagatact cagaaacaaa   2700

gccaaaatta agttcatcat taaaaagccc gaaatgtttg agacggcgat taaggagagc   2760

acctcctcta agagccctcc cagaaaaata aattcatcac ccaatgttaa tactactgca   2820

tcaggtgttg aagaccttaa catcattcag gtgacaattc cagatgatga taatgaaaga   2880

ctctcgaaag ttgaaaaagc tagacagcta agagaacaag tgaatgacct ctttagtcgg   2940

aaatttggtg aagctattgg tatgggtttt cctgtgaaag ttccctacag gaaaatcaca   3000

attaaccctg gctgtgtggt ggttgatggc atgcccccgg gggtgtcctt caaagccccc   3060

agctacctgg aaatcagctc catgagaagg atcttagact ctgccgagtt tatcaaattc   3120

acggtcatta gaccatttcc aggacttgtg attaataacc agctggttga tcagagtgag   3180

tcagaaggcc ccgtgataca agaatcagct gaaccaagcc agttggaagt tccagccaca   3240

gaagaaataa aagagactga tggaagctct cagatcaagc aagaaccaga ccccacgtgg   3300

tagacctctt ccctcctagg cttaaagtat cagtggttga gaagagcttt tcggacctgt   3360

tactacccca agctgtgtaa tatacttgta taacagaaat accttctata caaacctttt   3420

tttctacttt tagatagaaa tgtctacttt ttcagcagtt ctgtgaatta aagagcagag   3480

tgactgtggg tctggaatgg ctggtgtact tgggaatgta ctatcaggat tttacagcaa   3540

tgctgggaaa tgacagggaa aatgacagga atgaatctca ccagattttt tatgtactca   3600

gcagagcctt gagttacggt gtttattttc caatcaagtg aagatatctc ctacttctcc   3660

tactggaaca tctcagcttc tgcagtgaag aaaaattcct gtgatagttc agttctttag   3720

tttttctatt tgaaaaaaaa aaatcattta aatgatcctt tgttcacggc tctccttaat   3780

gactgagtga acagttccta tctgtatatt tgactaaacc ttttcctaag ctatctctca   3840

tggttcctat gtttttttat cataattaaa agcaaaacca tctggatcac ctaacagtca   3900

gaggtcagta tctcagcgtg tgaattatag aggaaataca gagagaacct cttccacttt   3960

tacttttcgt ccaaataaaa tgcatggtgt accagaagtt gaagatcggg ttgaggattg   4020

gggctagctc gatgacacta aggccccaac atcgcgggac ctgctgtggc gcggattctt   4080

aggaacgctg ttctagccgg ccccctctcc aggggtcgcc gtggccggca ttatttccta   4140

gttcttcttg taaccctgag gtgccagcgc ggggagtgag gaggggtcag ggggctaagg   4200

atgcaacctc tgacgttctg cgccttccta ggagagtctt acatgtgttg agatttcaca   4260

agcaatgcga gttgtaaaat accagctcta caagaagcta ggctctgtga cggcatagtt   4320

ttcagtagct ttatcacaat attcacaatg gagaattata tgacatggta gcagaaatag   4380

gcccttttat gtgttgcttc tattttacct caaattgtag atatagggta atcaataaaa   4440

tccatccatg cctttcacac actaagt                                       4467


<210>  5275
<211>  563
<212>  PRT
<213>  Homo sapiens

<400>  5275

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn 
    530                 535                 540


Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu 
545                 550                 555                 560


Lys Phe Ala 



<210>  5276
<211>  4936
<212>  DNA
<213>  Homo sapiens

<400>  5276
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agtcaaagaa gattggaatg tcagaattac caagctacgg aagcaagtgg   1860

aagagatttt taatttgaaa tttgctcaag ctcttggact caccgaggca gtaaaagtac   1920

catatcctgt gtttgaatca aacccggagt tcttgtatgt ggaaggcttg ccagagggga   1980

ttcccttccg aagccctacc tggtttggaa ttccacgact tgaaaggatc gtccgcggga   2040

gtaataaaat caagttcgtt gttaaaaaac ctgaactagt tatttcctac ttgcctcctg   2100

ggatggctag taaaataaac actaaagctt tgcagtcccc caaaagacca cgaagtcctg   2160

ggagtaattc aaaggttcct gaaattgagg tcaccgtgga aggccctaat aacaacaatc   2220

ctcaaacctc agctgttcga accccgaccc agactaacgg ttctaacgtt cccttcaagc   2280

cacgagggag agagttttcc tttgaggcct ggaatgccaa aatcacggac ctaaaacaga   2340

aagttgaaaa tctcttcaat gagaaatgtg gggaagctct tggccttaaa caagctgtga   2400

aggtgccgtt cgcgttattt gagtctttcc cggaagactt ttatgtggaa ggcttacctg   2460

agggtgtgcc attccgaaga ccatcgactt ttggcattcc gaggctggag aagatactca   2520

gaaacaaagc caaaattaag ttcatcatta aaaagcccga aatgtttgag acggcgatta   2580

aggagagcac ctcctctaag agccctccca gaaaaataaa ttcatcaccc aatgttaata   2640

ctactgcatc aggtgttgaa gaccttaaca tcattcaggt gacaattcca gatgatgata   2700

atgaaagact ctcgaaagtt gaaaaagcta gacagctaag agaacaagtg aatgacctct   2760

ttagtcggaa atttggtgaa gctattggta tgggttttcc tgtgaaagtt ccctacagga   2820

aaatcacaat taaccctggc tgtgtggtgg ttgatggcat gcccccgggg gtgtccttca   2880

aagcccccag ctacctggaa atcagctcca tgagaaggat cttagactct gccgagttta   2940

tcaaattcac ggtcattaga ccatttccag gacttgtgat taataaccag ctggttgatc   3000

agagtgagtc agaaggcccc gtgatacaag aatcagctga accaagccag ttggaagttc   3060

cagccacaga aggtaaaagg acctcttccc tcctagggta aatcagcttc tgtgtcaggg   3120

atgctgtgtg gtgtccatct gaaccccctg catacgcgta gctaatgtga tctccccact   3180

ttcacataag atggtggccc tgccttcagg gaatgtggga gccaggtggg agccttcccg   3240

gatatttaag ctagaagatt ctacagggag attctccttg gatcaatata tgtctctcag   3300

tcaaagatgt aaaagcactt ttgccttaaa aagaatgttc tgtttctaaa tagagtcaac   3360

gttgtcctcc tcattggaat tcactatgag tcagaatcat tagactgact tttttttttc   3420

catagtaata gtattttgca gagtctcaca gagctgcaga tcttttgttc atcttgcaga   3480

gttaacaagt ctgatcctgt tagtccagat ttcttaaatt tggccaagtt ataataggag   3540

cagtagcttg agacccgaag tcaggaaact ttgacaatgg attttttttt ttaatccaga   3600

gacttgtact ggaatttgcc ttaccctgtc agctcatgga cttaaggttt catcccgctt   3660

tatgagtgct tctgaatcca agtcattgtt acctgaattt gcaaattaag ttgtgatatt   3720

cgtgactgtt aaattcctgt aattagatta acctctttgc ttgcttgttt gttttctctc   3780

ctattttagc ttaaagtatc agtggttgag aagagctttt cggacctgtt actaccccaa   3840

gctgtgtaat atacttgtat aacagaaata ccttctatac aaaccttttt ttctactttt   3900

agatagaaat gtctactttt tcagcagttc tgtgaattaa agagcagagt gactgtgggt   3960

ctggaatggc tggtgtactt gggaatgtac tatcaggatt ttacagcaat gctgggaaat   4020

gacagggaaa atgacaggaa tgaatctcac cagatttttt atgtactcag cagagccttg   4080

agttacggtg tttattttcc aatcaagtga agatatctcc tacttctcct actggaacat   4140

ctcagcttct gcagtgaaga aaaattcctg tgatagttca gttctttagt ttttctattt   4200

gaaaaaaaaa aatcatttaa atgatccttt gttcacggct ctccttaatg actgagtgaa   4260

cagttcctat ctgtatattt gactaaacct tttcctaagc tatctctcat ggttcctatg   4320

tttttttatc ataattaaaa gcaaaaccat ctggatcacc taacagtcag aggtcagtat   4380

ctcagcgtgt gaattataga ggaaatacag agagaacctc ttccactttt acttttcgtc   4440

caaataaaat gcatggtgta ccagaagttg aagatcgggt tgaggattgg ggctagctcg   4500

atgacactaa ggccccaaca tcgcgggacc tgctgtggcg cggattctta ggaacgctgt   4560

tctagccggc cccctctcca ggggtcgccg tggccggcat tatttcctag ttcttcttgt   4620

aaccctgagg tgccagcgcg gggagtgagg aggggtcagg gggctaagga tgcaacctct   4680

gacgttctgc gccttcctag gagagtctta catgtgttga gatttcacaa gcaatgcgag   4740

ttgtaaaata ccagctctac aagaagctag gctctgtgac ggcatagttt tcagtagctt   4800

tatcacaata ttcacaatgg agaattatat gacatggtag cagaaatagg cccttttatg   4860

tgttgcttct attttacctc aaattgtaga tatagggtaa tcaataaaat ccatccatgc   4920

ctttcacaca ctaagt                                                   4936


<210>  5277
<211>  947
<212>  PRT
<213>  Homo sapiens

<400>  5277

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr 
        515                 520                 525


Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln 
    530                 535                 540


Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu 
545                 550                 555                 560


Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro 
                565                 570                 575


Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val 
            580                 585                 590


Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val 
        595                 600                 605


Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala 
    610                 615                 620


Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val 
625                 630                 635                 640


Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln 
                645                 650                 655


Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro 
            660                 665                 670


Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys 
        675                 680                 685


Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys 
    690                 695                 700


Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu 
705                 710                 715                 720


Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly 
                725                 730                 735


Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys 
            740                 745                 750


Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu 
        755                 760                 765


Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro 
    770                 775                 780


Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val 
785                 790                 795                 800


Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu 
                805                 810                 815


Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn 
            820                 825                 830


Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro 
        835                 840                 845


Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val 
    850                 855                 860


Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu 
865                 870                 875                 880


Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys 
                885                 890                 895


Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu 
            900                 905                 910


Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu 
        915                 920                 925


Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Gly Lys Arg Thr Ser Ser 
    930                 935                 940


Leu Leu Gly 
945


<210>  5278
<211>  3985
<212>  DNA
<213>  Homo sapiens

<400>  5278
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggaagccac cattcttcag    960

agggcaatga aggcacagaa atggaagtac cagcagaaga ttctactcaa catgtccctt   1020

cagaaacaag tgaggaccct gaagttgagg tgactattga agatgatgat tattctccac   1080

cgtctaagag accaaaggcc aatgagctac cgcagccacc agtcccggaa cccgccaatg   1140

ctgggaagcg gaaagtgagg gagttcaact tcgagaaatg gaatgctcgc atcactgatc   1200

tacgtaaaca agttgaagaa ttgtttgaaa ggaaatatgc tcaagccata aaagccaaag   1260

gtccggtgac gatcccgtac cctcttttcc agtctcatgt tgaagatctt tatgtagaag   1320

gacttcctga aggaattcct tttagaaggc catctactta cggaattcct cgcctggaga   1380

ggatattact tgcaaaggaa aggattcgtt ttgtgattaa gaaacatgag cttctgaatt   1440

caacacgtga agatttacag cttgataagc cagcttcagg agtaaaggaa gaatggtatg   1500

ccagaatcac taaattaaga aagatggtgg atcagctttt ctgcaaaaaa tttgcggaag   1560

ccttggggag cactgaagcc aaggctgtac cgtaccaaaa atttgaggca cacccgaatg   1620

atctgtacgt ggaaggactg ccagaaaaca ttcctttccg aagtccctca tggtatggaa   1680

tcccaaggct ggaaaaaatc attcaagtgg gcaatcgaat taaatttgtt attaaaagac   1740

cagaacttct gactcacagt accactgaag ttactcagcc aagaacgaat acaccagtca   1800

aagaagattg gaatgtcaga attaccaagc tacggaagca agtggaagag atttttaatt   1860

tgaaatttgc tcaagctctt ggactcaccg aggcagtaaa agtaccatat cctgtgtttg   1920

aatcaaaccc ggagttcttg aaaggatcgt ccgcgggagt aataaaatca agttcgttgt   1980

taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta aaataaacac   2040

taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa aggttcctga   2100

aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag ctgttcgaac   2160

cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag agttttcctt   2220

tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc tcttcaatga   2280

gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg cgttatttga   2340

gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat tccgaagacc   2400

atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca aaattaagtt   2460

catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct cctctaagag   2520

ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag gtgttgaaga   2580

ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct cgaaagttga   2640

aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat ttggtgaagc   2700

tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta accctggctg   2760

tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct acctggaaat   2820

cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg tcattagacc   2880

atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag aaggccccgt   2940

gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag aaataaaaga   3000

gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga cctcttccct   3060

cctaggctta aagtatcagt ggttgagaag agcttttcgg acctgttact accccaagct   3120

gtagccttga gttacggtgt ttattttcca atcaagtgaa gatatctcct acttctccta   3180

ctggaacatc tcagcttctg cagtgaagaa aaattcctgt gatagttcag ttctttagtt   3240

tttctatttg aaaaaaaaaa atcatttaaa tgatcctttg ttcacggctc tccttaatga   3300

ctgagtgaac agttcctatc tgtatatttg actaaacctt ttcctaagct atctctcatg   3360

gttcctatgt ttttttatca taattaaaag caaaaccatc tggatcacct aacagtcaga   3420

ggtcagtatc tcagcgtgtg aattatagag gaaatacaga gagaacctct tccactttta   3480

cttttcgtcc aaataaaatg catggtgtac cagaagttga agatcgggtt gaggattggg   3540

gctagctcga tgacactaag gccccaacat cgcgggacct gctgtggcgc ggattcttag   3600

gaacgctgtt ctagccggcc ccctctccag gggtcgccgt ggccggcatt atttcctagt   3660

tcttcttgta accctgaggt gccagcgcgg ggagtgagga ggggtcaggg ggctaaggat   3720

gcaacctctg acgttctgcg ccttcctagg agagtcttac atgtgttgag atttcacaag   3780

caatgcgagt tgtaaaatac cagctctaca agaagctagg ctctgtgacg gcatagtttt   3840

cagtagcttt atcacaatat tcacaatgga gaattatatg acatggtagc agaaataggc   3900

ccttttatgt gttgcttcta ttttacctca aattgtagat atagggtaat caataaaatc   3960

catccatgcc tttcacacac taagt                                         3985


<210>  5279
<211>  579
<212>  PRT
<213>  Homo sapiens

<400>  5279

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr 
225                 230                 235                 240


Glu Met Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu 
                245                 250                 255


Thr Ser Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr 
            260                 265                 270


Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro 
        275                 280                 285


Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn 
    290                 295                 300


Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu 
305                 310                 315                 320


Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro 
                325                 330                 335


Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr 
            340                 345                 350


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr 
        355                 360                 365


Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg 
    370                 375                 380


Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu 
385                 390                 395                 400


Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg 
                405                 410                 415


Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe 
            420                 425                 430


Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys 
        435                 440                 445


Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn 
    450                 455                 460


Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys 
465                 470                 475                 480


Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu 
                485                 490                 495


Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr 
            500                 505                 510


Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln 
        515                 520                 525


Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr 
    530                 535                 540


Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe 
545                 550                 555                 560


Leu Lys Gly Ser Ser Ala Gly Val Ile Lys Ser Ser Ser Leu Leu Lys 
                565                 570                 575


Asn Leu Asn 



<210>  5280
<211>  3929
<212>  DNA
<213>  Homo sapiens

<400>  5280
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggaagccac cattcttcag    960

agggcaatga aggcacagaa atggaagtac cagcagaaga ttctactcaa catgtccctt   1020

cagaaacaag tgaggaccct gaagttgagg tgactattga agatgatgat tattctccac   1080

cgtctaagag accaaaggcc aatgagctac cgcagccacc agtcccggaa cccgccaatg   1140

ctgggaagcg gaaagtgagg gagttcaact tcgagaaatg gaatgctcgc atcactgatc   1200

tacgtaaaca agttgaagaa ttgtttgaaa ggaaatatgc tcaagccata aaagccaaag   1260

gtccggtgac gatcccgtac cctcttttcc agtctcatgt tgaagatctt tatgtagaag   1320

gacttcctga aggaattcct tttagaaggc catctactta cggaattcct cgcctggaga   1380

ggatattact tgcaaaggaa aggattcgtt ttgtgattaa gaaacatgag cttctgaatt   1440

caacacgtga agatttacag cttgataagc cagcttcagg agtaaaggaa gaatggtatg   1500

ccagaatcac taaattaaga aagatggtgg atcagctttt ctgcaaaaaa tttgcggaag   1560

ccttggggag cactgaagcc aaggctgtac cgtaccaaaa atttgaggca cacccgaatg   1620

atctgtacgt ggaaggactg ccagaaaaca ttcctttccg aagtccctca tggtatggaa   1680

tcccaaggct ggaaaaaatc attcaagtgg gcaatcgaat taaatttgtt attaaaagac   1740

cagaacttct gactcacagt accactgaag ttactcagcc aagaacgaat acaccagtca   1800

aagaagattg gaatgtcaga attaccaagc tacggaagca agtggaagag atttttaatt   1860

tgaaatttgc tcaagctctt ggactcaccg aggcagtaaa agtaccatat cctgtgtttg   1920

aatcaaaccc ggagttcttg aaaggatcgt ccgcgggagt aataaaatca agttcgttgt   1980

taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta aaataaacac   2040

taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa aggttcctga   2100

aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag ctgttcgaac   2160

cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag agttttcctt   2220

tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc tcttcaatga   2280

gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg cgttatttga   2340

gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat tccgaagacc   2400

atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca aaattaagtt   2460

catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct cctctaagag   2520

ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag gtgttgaaga   2580

ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct cgaaagttga   2640

aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat ttggtgaagc   2700

tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta accctggctg   2760

tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct acctggaaat   2820

cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg tcattagacc   2880

atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag aaggccccgt   2940

gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag aaataaaaga   3000

gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga cctcttccct   3060

cctaggagcc ttgagttacg gtgtttattt tccaatcaag tgaagatatc tcctacttct   3120

cctactggaa catctcagct tctgcagtga agaaaaattc ctgtgatagt tcagttcttt   3180

agtttttcta tttgaaaaaa aaaaatcatt taaatgatcc tttgttcacg gctctcctta   3240

atgactgagt gaacagttcc tatctgtata tttgactaaa ccttttccta agctatctct   3300

catggttcct atgttttttt atcataatta aaagcaaaac catctggatc acctaacagt   3360

cagaggtcag tatctcagcg tgtgaattat agaggaaata cagagagaac ctcttccact   3420

tttacttttc gtccaaataa aatgcatggt gtaccagaag ttgaagatcg ggttgaggat   3480

tggggctagc tcgatgacac taaggcccca acatcgcggg acctgctgtg gcgcggattc   3540

ttaggaacgc tgttctagcc ggccccctct ccaggggtcg ccgtggccgg cattatttcc   3600

tagttcttct tgtaaccctg aggtgccagc gcggggagtg aggaggggtc agggggctaa   3660

ggatgcaacc tctgacgttc tgcgccttcc taggagagtc ttacatgtgt tgagatttca   3720

caagcaatgc gagttgtaaa ataccagctc tacaagaagc taggctctgt gacggcatag   3780

ttttcagtag ctttatcaca atattcacaa tggagaatta tatgacatgg tagcagaaat   3840

aggccctttt atgtgttgct tctattttac ctcaaattgt agatataggg taatcaataa   3900

aatccatcca tgcctttcac acactaagt                                     3929


<210>  5281
<211>  579
<212>  PRT
<213>  Homo sapiens

<400>  5281

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr 
225                 230                 235                 240


Glu Met Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu 
                245                 250                 255


Thr Ser Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr 
            260                 265                 270


Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro 
        275                 280                 285


Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn 
    290                 295                 300


Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu 
305                 310                 315                 320


Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro 
                325                 330                 335


Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr 
            340                 345                 350


Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr 
        355                 360                 365


Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg 
    370                 375                 380


Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu 
385                 390                 395                 400


Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg 
                405                 410                 415


Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe 
            420                 425                 430


Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys 
        435                 440                 445


Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn 
    450                 455                 460


Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys 
465                 470                 475                 480


Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu 
                485                 490                 495


Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr 
            500                 505                 510


Pro Val Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln 
        515                 520                 525


Val Glu Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr 
    530                 535                 540


Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe 
545                 550                 555                 560


Leu Lys Gly Ser Ser Ala Gly Val Ile Lys Ser Ser Ser Leu Leu Lys 
                565                 570                 575


Asn Leu Asn 



<210>  5282
<211>  7923
<212>  DNA
<213>  Homo sapiens

<400>  5282
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctt agatttgttg acagcggttt cctggagtgc   1980

tgtcttgaga acgattctga ggaggctcag caagaaagag tgtttcagtt gattgggtgt   2040

gtctgtcatg gagaaggaac tcaagctctt ggactcaccg aggcagtaaa agtaccatat   2100

cctgtgtttg aatcaaaccc ggagttcttg tatgtggaag gcttgccaga ggggattccc   2160

ttccgaagcc ctacctggtt tggaattcca cgacttgaaa ggatcgtccg cgggagtaat   2220

aaaatcaagt tcgttgttaa aaaacctgaa ctagttattt cctacttgcc tcctgggatg   2280

gctagtaaaa taaacactaa agctttgcag tcccccaaaa gaccacgaag tcctgggagt   2340

aattcaaagg ttcctgaaat tgaggtcacc gtggaaggcc ctaataacaa caatcctcaa   2400

acctcagctg ttcgaacccc gacccagact aacggttcta acgttccctt caagccacga   2460

gggagagagt tttcctttga ggcctggaat gccaaaatca cggacctaaa acagaaagtt   2520

gaaaatctct tcaatgagaa atgtggggaa gctcttggcc ttaaacaagc tgtgaaggtg   2580

ccgttcgcgt tatttgagtc tttcccggaa gacttttatg tggaaggctt acctgagggt   2640

gtgccattcc gaagaccatc gacttttggc attccgaggc tggagaagat actcagaaac   2700

aaagccaaaa ttaagttcat cattaaaaag cccgaaatgt ttgagacggc gattaaggag   2760

agcacctcct ctaagagccc tcccagaaaa ataaattcat cacccaatgt taatactact   2820

gcatcaggtg ttgaagacct taacatcatt caggtgacaa ttccagatga tgataatgaa   2880

agactctcga aagttgaaaa agctagacag ctaagagaac aagtgaatga cctctttagt   2940

cggaaatttg gtgaagctat tggtatgggt tttcctgtga aagttcccta caggaaaatc   3000

acaattaacc ctggctgtgt ggtggttgat ggcatgcccc cgggggtgtc cttcaaagcc   3060

cccagctacc tggaaatcag ctccatgaga aggatcttag actctgccga gtttatcaaa   3120

ttcacggtca ttaggtaagt gagagtttcc tgcttagtca caggagcgaa tctggagctc   3180

atgaggctga ctcttctaaa atgcagccac aggtagtcat cgaatccggc ttcctatgct   3240

gtgcaatcaa caaatcaaaa taacttgtgt catcattaga atgtcagatg tgcttctacg   3300

aactaagctg actcttttaa ttctttggca aagggttggc aaactaggac tgtttgccaa   3360

attcaggctg cctcctattt ttagagtctt cctgaaacac agctacaccc gtattatcca   3420

tggctgcttt cctgtcacag tgagtaagta gctgggactg agaaggcatg gcctccaaag   3480

tctaaaatat ttactctcta gcactttgta gaaaaacctt agctaggcac agtggctaac   3540

gcctgtaatc ccagcatttt gggaggccaa ggcaggcaga tcacctgagg tcaggagttc   3600

cagaccagcc tggccaacat ggtgaaatcc catctctaca aaaataaaac agttagctgg   3660

gcatgatggc gggtgcctgt aatcccagct actcgggagg ctgaggcagg atagtcgctt   3720

gaacccagga ggtggaggtt gcaatgagcc aagatcatgc cactgcactc cagcctggac   3780

gacagagtga gactccatca caagaaaaaa agaactttgt caacctctgt cttagggcgc   3840

cttgtcacag gcttcgggtc agacggattc aaccttgcat cagccatttg ttagccaggt   3900

cactctgttc tttgtctgta aatgagattg atcgttgttc ccactgagag tgtcagctcc   3960

ttcccgtaga gcaggcatga tgattgtact cacctctgac accattgtga gtgccacatt   4020

ccttcccacg tccttgtcac tgtaagagat gcccacctga gcaccaaccc caggttatct   4080

tcccctttgt cttccagccc cccagaaaca gctacgactc aacctaccca atcatttcat   4140

catcagattg ccactgtctc tagttcaggt ctcttgggac tggcactcag aaatctcata   4200

ataaatcctc ttgaggcttc tcatacactc gtcttcttcc aatcttcttt ccctcaaaat   4260

ctcatatttt ggttccactt cacccaccgt cattctccat atcactccca ggagttaggc   4320

aaaaagcccc ttccgttctt ccgtatgtta aacttagaat cactctgttc cctgctctgc   4380

gtttctattt tttgtttttc ctccatttac tagtagctta acactttcta acagtgttct   4440

tattattgat acgtatctat ctcttccata agcttataag gtcacggata atacttctca   4500

ttgtagtacg taaatgacgt gggctagata tgagttgaat aaacagttat acctgtaaat   4560

tcttacagag tgaaaataaa ttgttatact ttacaatttg tttctctctt tagaccattt   4620

ccaggacttg tgattaataa ccgtgagtat tttgtgaagt gttttgtttt tgttttttcc   4680

tggggtctga cgtgtgtgcg tgtgagtgtg tatacatgct taacgtatat cacgttactt   4740

cacctatgtc agtaaccagg ccaaatactt gttttagccc tcagtaaaaa caccaggcac   4800

ttcctagttg taaaattatt caagcttctt aacttcctat cctcgatgca cttaatcata   4860

aaatggtaat aatagcaccg attttggggg agtcgttcca gtagatggaa agcatctgga   4920

acaggtgtca gcaagctcct gccgacgtgt atgcataaag ttttattgaa accaccatcg   4980

tgtccatttg tttatggcag aactgagaga tggcagcagc aagtgtgtgc ctgcaaaacc   5040

taaaatattt actaattggc tctgcaagaa aagagtttgc atccccctaa cctagaacag   5100

tgtctagcct ctagtatgtg tttagcctac agtatgtgct cagcgaatac aatctatatt   5160

tattactgct tttatgactg ttataattac tgtgcttgga tttcgttaca aagtaagtca   5220

caatgtgcct gcttctgtta gtatttcagc acagtgcctg gcacacatgg ggctctcaaa   5280

tattgctgag cgagtgaaca aatgtccttt caattcctta acgttgatgt cattttcaat   5340

agtattttga gccaaactta attttgcgag tgtgttttgt tttcttaact ttattattaa   5400

aaatgtataa aagtgaggcc aggcgtggtg gctcacgcct gtaatcccag cagtttggga   5460

ggctgaggca ggcggatcag ttgaggttgg gagttggaga ccagcccgtc caacatggtg   5520

aaagcctgtc tctactaaaa atacaaaaat cagctgggtg tggtggcgcg tgcctgtaat   5580

cccagctact caggaggctg aggcaggaga gttgcttgaa tcctagaggt ggaggttgca   5640

gtgagctgag atcgtgccat tgcactccag cctgggcaac aagagcaaaa ctctgtccca   5700

ataaataaat aaataaaatg ttctcttttg ttcctgttct tgtgcggtag tgtggtatag   5760

agttttatgg taattactgt gaattagtga ttctgaggga catatcagaa ctctgaggtt   5820

tgtttccttc tcatcttgag ggaaacagca aatgtatgtt aaaatgcttt tccaagggaa   5880

caacacatcc ttacattatt taaaccaatc tgcttcattt tcagagctgg ttgatcagag   5940

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   6000

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   6060

gtggtagacc tcttccctcc tagggtaaat cagcttctgt gtcagggatg ctgtgtggtg   6120

tccatctgaa ccccctgcat acgcgtagct aatgtgatct ccccactttc acataagatg   6180

gtggccctgc cttcagggaa tgtgggagcc aggtgggagc cttcccggat atttaagcta   6240

gaagattcta cagggagatt ctccttggat caatatatgt ctctcagtca aagatgtaaa   6300

agcacttttg ccttaaaaag aatgttctgt ttctaaatag agtcaacgtt gtcctcctca   6360

ttggaattca ctatgagtca gaatcattag actgactttt ttttttccat agtaatagta   6420

ttttgcagag tctcacagag ctgcagatct tttgttcatc ttgcagagtt aacaagtctg   6480

atcctgttag tccagatttc ttaaatttgg ccaagttata ataggagcag tagcttgaga   6540

cccgaagtca ggaaactttg acaatggatt ttttttttta atccagagac ttgtactgga   6600

atttgcctta ccctgtcagc tcatggactt aaggtttcat cccgctttat gagtgcttct   6660

gaatccaagt cattgttacc tgaatttgca aattaagttg tgatattcgt gactgttaaa   6720

ttcctgtaat tagattaacc tctttgcttg cttgtttgtt ttctctccta ttttagctta   6780

aagtatcagt ggttgagaag agcttttcgg acctgttact accccaagct gtgtaatata   6840

cttgtataac agaaatacct tctatacaaa cctttttttc tacttttaga tagaaatgtc   6900

tactttttca gcagttctgt gaattaaaga gcagagtgac tgtgggtctg gaatggctgg   6960

tgtacttggg aatgtactat caggatttta cagcaatgct gggaaatgac agggaaaatg   7020

acaggaatga atctcaccag attttttatg tactcagcag agccttgagt tacggtgttt   7080

attttccaat caagtgaaga tatctcctac ttctcctact ggaacatctc agcttctgca   7140

gtgaagaaaa attcctgtga tagttcagtt ctttagtttt tctatttgaa aaaaaaaaat   7200

catttaaatg atcctttgtt cacggctctc cttaatgact gagtgaacag ttcctatctg   7260

tatatttgac taaacctttt cctaagctat ctctcatggt tcctatgttt ttttatcata   7320

attaaaagca aaaccatctg gatcacctaa cagtcagagg tcagtatctc agcgtgtgaa   7380

ttatagagga aatacagaga gaacctcttc cacttttact tttcgtccaa ataaaatgca   7440

tggtgtacca gaagttgaag atcgggttga ggattggggc tagctcgatg acactaaggc   7500

cccaacatcg cgggacctgc tgtggcgcgg attcttagga acgctgttct agccggcccc   7560

ctctccaggg gtcgccgtgg ccggcattat ttcctagttc ttcttgtaac cctgaggtgc   7620

cagcgcgggg agtgaggagg ggtcaggggg ctaaggatgc aacctctgac gttctgcgcc   7680

ttcctaggag agtcttacat gtgttgagat ttcacaagca atgcgagttg taaaatacca   7740

gctctacaag aagctaggct ctgtgacggc atagttttca gtagctttat cacaatattc   7800

acaatggaga attatatgac atggtagcag aaataggccc ttttatgtgt tgcttctatt   7860

ttacctcaaa ttgtagatat agggtaatca ataaaatcca tccatgcctt tcacacacta   7920

agt                                                                 7923


<210>  5283
<211>  564
<212>  PRT
<213>  Homo sapiens

<400>  5283

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala 



<210>  5284
<211>  4346
<212>  DNA
<213>  Homo sapiens

<400>  5284
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagctcaa gctcttggac tcaccgaggc agtaaaagta ccatatcctg   1980

tgtttgaatc aaacccggag ttcttgtatg tggaaggctt gccagagggg attcccttcc   2040

gaagccctac ctggtttgga attccacgac ttgaaaggat cgtccgcggg agtaataaaa   2100

tcaagttcgt tgttaaaaaa cctgaactag ttatttccta cttgcctcct gggatggcta   2160

gtaaaataaa cactaaagct ttgcagtccc ccaaaagacc acgaagtcct gggagtaatt   2220

caaaggttcc tgaaattgag gtcaccgtgg aaggccctaa taacaacaat cctcaaacct   2280

cagctgttcg aaccccgacc cagactaacg gttctaacgt tcccttcaag ccacgaggga   2340

gagagttttc ctttgaggcc tggaatgcca aaatcacgga cctaaaacag aaagttgaaa   2400

atctcttcaa tgagaaatgt ggggaagctc ttggccttaa acaagctgtg aaggtgccgt   2460

tcgcgttatt tgagtctttc ccggaagact tttatgtgga aggcttacct gagggtgtgc   2520

cattccgaag accatcgact tttggcattc cgaggctgga gaagatactc agaaacaaag   2580

ccaaaattaa gttcatcatt aaaaagcccg aaatgtttga gacggcgatt aaggagagca   2640

cctcctctaa gagccctccc agaaaaataa attcatcacc caatgttaat actactgcat   2700

caggtgttga agaccttaac atcattcagg tgacaattcc agatgatgat aatgaaagac   2760

tctcgaaagt tgaaaaagct agacagctaa gagaacaagt gaatgacctc tttagtcgga   2820

aatttggtga agctattggt atgggttttc ctgtgaaagt tccctacagg aaaatcacaa   2880

ttaaccctgg ctgtgtggtg gttgatggca tgcccccggg ggtgtccttc aaagccccca   2940

gctacctgga aatcagctcc atgagaagga tcttagactc tgccgagttt atcaaattca   3000

cggtcattag accatttcca ggacttgtga ttaataacca gctggttgat cagagtgagt   3060

cagaaggccc cgtgatacaa gaatcagctg aaccaagcca gttggaagtt ccagccacag   3120

aagaaataaa agagactgat ggaagctctc agatcaagca agaaccagac cccacgtggt   3180

agacctcttc cctcctaggc ttaaagtatc agtggttgag aagagctttt cggacctgtt   3240

actaccccaa gctgtgtaat atacttgtat aacagaaata ccttctatac aaaccttttt   3300

ttctactttt agatagaaat gtctactttt tcagcagttc tgtgaattaa agagcagagt   3360

gactgtgggt ctggaatggc tggtgtactt gggaatgtac tatcaggatt ttacagcaat   3420

gctgggaaat gacagggaaa atgacaggaa tgaatctcac cagatttttt atgtactcag   3480

cagagccttg agttacggtg tttattttcc aatcaagtga agatatctcc tacttctcct   3540

actggaacat ctcagcttct gcagtgaaga aaaattcctg tgatagttca gttctttagt   3600

ttttctattt gaaaaaaaaa aatcatttaa atgatccttt gttcacggct ctccttaatg   3660

actgagtgaa cagttcctat ctgtatattt gactaaacct tttcctaagc tatctctcat   3720

ggttcctatg tttttttatc ataattaaaa gcaaaaccat ctggatcacc taacagtcag   3780

aggtcagtat ctcagcgtgt gaattataga ggaaatacag agagaacctc ttccactttt   3840

acttttcgtc caaataaaat gcatggtgta ccagaagttg aagatcgggt tgaggattgg   3900

ggctagctcg atgacactaa ggccccaaca tcgcgggacc tgctgtggcg cggattctta   3960

ggaacgctgt tctagccggc cccctctcca ggggtcgccg tggccggcat tatttcctag   4020

ttcttcttgt aaccctgagg tgccagcgcg gggagtgagg aggggtcagg gggctaagga   4080

tgcaacctct gacgttctgc gccttcctag gagagtctta catgtgttga gatttcacaa   4140

gcaatgcgag ttgtaaaata ccagctctac aagaagctag gctctgtgac ggcatagttt   4200

tcagtagctt tatcacaata ttcacaatgg agaattatat gacatggtag cagaaatagg   4260

cccttttatg tgttgcttct attttacctc aaattgtaga tatagggtaa tcaataaaat   4320

ccatccatgc ctttcacaca ctaagt                                        4346


<210>  5285
<211>  974
<212>  PRT
<213>  Homo sapiens

<400>  5285

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Ala 
545                 550                 555                 560


Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe 
                565                 570                 575


Glu Ser Asn Pro Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile 
            580                 585                 590


Pro Phe Arg Ser Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile 
        595                 600                 605


Val Arg Gly Ser Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu 
    610                 615                 620


Val Ile Ser Tyr Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys 
625                 630                 635                 640


Ala Leu Gln Ser Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys 
                645                 650                 655


Val Pro Glu Ile Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro 
            660                 665                 670


Gln Thr Ser Ala Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val 
        675                 680                 685


Pro Phe Lys Pro Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala 
    690                 695                 700


Lys Ile Thr Asp Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys 
705                 710                 715                 720


Cys Gly Glu Ala Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala 
                725                 730                 735


Leu Phe Glu Ser Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu 
            740                 745                 750


Gly Val Pro Phe Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu 
        755                 760                 765


Lys Ile Leu Arg Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro 
    770                 775                 780


Glu Met Phe Glu Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro 
785                 790                 795                 800


Pro Arg Lys Ile Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly 
                805                 810                 815


Val Glu Asp Leu Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn 
            820                 825                 830


Glu Arg Leu Ser Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val 
        835                 840                 845


Asn Asp Leu Phe Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe 
    850                 855                 860


Pro Val Lys Val Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val 
865                 870                 875                 880


Val Val Asp Gly Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr 
                885                 890                 895


Leu Glu Ile Ser Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile 
            900                 905                 910


Lys Phe Thr Val Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln 
        915                 920                 925


Leu Val Asp Gln Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala 
    930                 935                 940


Glu Pro Ser Gln Leu Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr 
945                 950                 955                 960


Asp Gly Ser Ser Gln Ile Lys Gln Glu Pro Asp Pro Thr Trp 
                965                 970


<210>  5286
<211>  4283
<212>  DNA
<213>  Homo sapiens

<400>  5286
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1140

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1200

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1260

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1320

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1380

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1440

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1500

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1560

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1620

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1680

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1740

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1800

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1860

cgaatacacc agctcaagct cttggactca ccgaggcagt aaaagtacca tatcctgtgt   1920

ttgaatcaaa cccggagttc ttgtatgtgg aaggcttgcc agaggggatt cccttccgaa   1980

gccctacctg gtttggaatt ccacgacttg aaaggatcgt ccgcgggagt aataaaatca   2040

agttcgttgt taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta   2100

aaataaacac taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa   2160

aggttcctga aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag   2220

ctgttcgaac cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag   2280

agttttcctt tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc   2340

tcttcaatga gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg   2400

cgttatttga gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat   2460

tccgaagacc atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca   2520

aaattaagtt catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct   2580

cctctaagag ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag   2640

gtgttgaaga ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct   2700

cgaaagttga aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat   2760

ttggtgaagc tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta   2820

accctggctg tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct   2880

acctggaaat cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg   2940

tcattagacc atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag   3000

aaggccccgt gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag   3060

aaataaaaga gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga   3120

cctcttccct cctaggctta aagtatcagt ggttgagaag agcttttcgg acctgttact   3180

accccaagct gtgtaatata cttgtataac agaaatacct tctatacaaa cctttttttc   3240

tacttttaga tagaaatgtc tactttttca gcagttctgt gaattaaaga gcagagtgac   3300

tgtgggtctg gaatggctgg tgtacttggg aatgtactat caggatttta cagcaatgct   3360

gggaaatgac agggaaaatg acaggaatga atctcaccag attttttatg tactcagcag   3420

agccttgagt tacggtgttt attttccaat caagtgaaga tatctcctac ttctcctact   3480

ggaacatctc agcttctgca gtgaagaaaa attcctgtga tagttcagtt ctttagtttt   3540

tctatttgaa aaaaaaaaat catttaaatg atcctttgtt cacggctctc cttaatgact   3600

gagtgaacag ttcctatctg tatatttgac taaacctttt cctaagctat ctctcatggt   3660

tcctatgttt ttttatcata attaaaagca aaaccatctg gatcacctaa cagtcagagg   3720

tcagtatctc agcgtgtgaa ttatagagga aatacagaga gaacctcttc cacttttact   3780

tttcgtccaa ataaaatgca tggtgtacca gaagttgaag atcgggttga ggattggggc   3840

tagctcgatg acactaaggc cccaacatcg cgggacctgc tgtggcgcgg attcttagga   3900

acgctgttct agccggcccc ctctccaggg gtcgccgtgg ccggcattat ttcctagttc   3960

ttcttgtaac cctgaggtgc cagcgcgggg agtgaggagg ggtcaggggg ctaaggatgc   4020

aacctctgac gttctgcgcc ttcctaggag agtcttacat gtgttgagat ttcacaagca   4080

atgcgagttg taaaatacca gctctacaag aagctaggct ctgtgacggc atagttttca   4140

gtagctttat cacaatattc acaatggaga attatatgac atggtagcag aaataggccc   4200

ttttatgtgt tgcttctatt ttacctcaaa ttgtagatat agggtaatca ataaaatcca   4260

tccatgcctt tcacacacta agt                                           4283


<210>  5287
<211>  953
<212>  PRT
<213>  Homo sapiens

<400>  5287

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro 
    290                 295                 300


Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala 
305                 310                 315                 320


Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg 
                325                 330                 335


Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr 
            340                 345                 350


Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu 
        355                 360                 365


Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly 
    370                 375                 380


Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg 
385                 390                 395                 400


Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu 
                405                 410                 415


Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser 
            420                 425                 430


Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met 
        435                 440                 445


Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr 
    450                 455                 460


Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp 
465                 470                 475                 480


Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser 
                485                 490                 495


Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg 
            500                 505                 510


Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr 
        515                 520                 525


Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly Leu 
    530                 535                 540


Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu 
545                 550                 555                 560


Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro 
                565                 570                 575


Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn 
            580                 585                 590


Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu 
        595                 600                 605


Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro 
    610                 615                 620


Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu 
625                 630                 635                 640


Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val 
                645                 650                 655


Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg 
            660                 665                 670


Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu 
        675                 680                 685


Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu 
    690                 695                 700


Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe 
705                 710                 715                 720


Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg 
                725                 730                 735


Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn 
            740                 745                 750


Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr 
        755                 760                 765


Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn 
    770                 775                 780


Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn 
785                 790                 795                 800


Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys 
                805                 810                 815


Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser 
            820                 825                 830


Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro 
        835                 840                 845


Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met 
    850                 855                 860


Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser 
865                 870                 875                 880


Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile 
                885                 890                 895


Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser 
            900                 905                 910


Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu 
        915                 920                 925


Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln 
    930                 935                 940


Ile Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950


<210>  5288
<211>  4915
<212>  DNA
<213>  Homo sapiens

<400>  5288
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatg   1080

atgattattc tccaccgtct aagagaccaa aggccaatga gctaccgcag ccaccagtcc   1140

cggaacccgc caatgctggg aagcggaaag tgagggagtt caacttcgag aaatggaatg   1200

ctcgcatcac tgatctacgt aaacaagttg aagaattgtt tgaaaggaaa tatgctcaag   1260

ccataaaagc caaaggtccg gtgacgatcc cgtaccctct tttccagtct catgttgaag   1320

atctttatgt agaaggactt cctgaaggaa ttccttttag aaggccatct acttacggaa   1380

ttcctcgcct ggagaggata ttacttgcaa aggaaaggat tcgttttgtg attaagaaac   1440

atgagcttct gaattcaaca cgtgaagatt tacagcttga taagccagct tcaggagtaa   1500

aggaagaatg gtatgccaga atcactaaat taagaaagat ggtggatcag cttttctgca   1560

aaaaatttgc ggaagccttg gggagcactg aagccaaggc tgtaccgtac caaaaatttg   1620

aggcacaccc gaatgatctg tacgtggaag gactgccaga aaacattcct ttccgaagtc   1680

cctcatggta tggaatccca aggctggaaa aaatcattca agtgggcaat cgaattaaat   1740

ttgttattaa aagaccagaa cttctgactc acagtaccac tgaagttact cagccaagaa   1800

cgaatacacc agctcaagct cttggactca ccgaggcagt aaaagtacca tatcctgtgt   1860

ttgaatcaaa cccggagttc ttgtatgtgg aaggcttgcc agaggggatt cccttccgaa   1920

gccctacctg gtttggaatt ccacgacttg aaaggatcgt ccgcgggagt aataaaatca   1980

agttcgttgt taaaaaacct gaactagtta tttcctactt gcctcctggg atggctagta   2040

aaataaacac taaagctttg cagtccccca aaagaccacg aagtcctggg agtaattcaa   2100

aggttcctga aattgaggtc accgtggaag gccctaataa caacaatcct caaacctcag   2160

ctgttcgaac cccgacccag actaacggtt ctaacgttcc cttcaagcca cgagggagag   2220

agttttcctt tgaggcctgg aatgccaaaa tcacggacct aaaacagaaa gttgaaaatc   2280

tcttcaatga gaaatgtggg gaagctcttg gccttaaaca agctgtgaag gtgccgttcg   2340

cgttatttga gtctttcccg gaagactttt atgtggaagg cttacctgag ggtgtgccat   2400

tccgaagacc atcgactttt ggcattccga ggctggagaa gatactcaga aacaaagcca   2460

aaattaagtt catcattaaa aagcccgaaa tgtttgagac ggcgattaag gagagcacct   2520

cctctaagag ccctcccaga aaaataaatt catcacccaa tgttaatact actgcatcag   2580

gtgttgaaga ccttaacatc attcaggtga caattccaga tgatgataat gaaagactct   2640

cgaaagttga aaaagctaga cagctaagag aacaagtgaa tgacctcttt agtcggaaat   2700

ttggtgaagc tattggtatg ggttttcctg tgaaagttcc ctacaggaaa atcacaatta   2760

accctggctg tgtggtggtt gatggcatgc ccccgggggt gtccttcaaa gcccccagct   2820

acctggaaat cagctccatg agaaggatct tagactctgc cgagtttatc aaattcacgg   2880

tcattagacc atttccagga cttgtgatta ataaccagct ggttgatcag agtgagtcag   2940

aaggccccgt gatacaagaa tcagctgaac caagccagtt ggaagttcca gccacagaag   3000

aaataaaaga gactgatgga agctctcaga tcaagcaaga accagacccc acgtggtaga   3060

cctcttccct cctagggtaa atcagcttct gtgtcaggga tgctgtgtgg tgtccatctg   3120

aaccccctgc atacgcgtag ctaatgtgat ctccccactt tcacataaga tggtggccct   3180

gccttcaggg aatgtgggag ccaggtggga gccttcccgg atatttaagc tagaagattc   3240

tacagggaga ttctccttgg atcaatatat gtctctcagt caaagatgta aaagcacttt   3300

tgccttaaaa agaatgttct gtttctaaat agagtcaacg ttgtcctcct cattggaatt   3360

cactatgagt cagaatcatt agactgactt ttttttttcc atagtaatag tattttgcag   3420

agtctcacag agctgcagat cttttgttca tcttgcagag ttaacaagtc tgatcctgtt   3480

agtccagatt tcttaaattt ggccaagtta taataggagc agtagcttga gacccgaagt   3540

caggaaactt tgacaatgga tttttttttt taatccagag acttgtactg gaatttgcct   3600

taccctgtca gctcatggac ttaaggtttc atcccgcttt atgagtgctt ctgaatccaa   3660

gtcattgtta cctgaatttg caaattaagt tgtgatattc gtgactgtta aattcctgta   3720

attagattaa cctctttgct tgcttgtttg ttttctctcc tattttagct taaagtatca   3780

gtggttgaga agagcttttc ggacctgtta ctaccccaag ctgtgtaata tacttgtata   3840

acagaaatac cttctataca aacctttttt tctactttta gatagaaatg tctacttttt   3900

cagcagttct gtgaattaaa gagcagagtg actgtgggtc tggaatggct ggtgtacttg   3960

ggaatgtact atcaggattt tacagcaatg ctgggaaatg acagggaaaa tgacaggaat   4020

gaatctcacc agatttttta tgtactcagc agagccttga gttacggtgt ttattttcca   4080

atcaagtgaa gatatctcct acttctccta ctggaacatc tcagcttctg cagtgaagaa   4140

aaattcctgt gatagttcag ttctttagtt tttctatttg aaaaaaaaaa atcatttaaa   4200

tgatcctttg ttcacggctc tccttaatga ctgagtgaac agttcctatc tgtatatttg   4260

actaaacctt ttcctaagct atctctcatg gttcctatgt ttttttatca taattaaaag   4320

caaaaccatc tggatcacct aacagtcaga ggtcagtatc tcagcgtgtg aattatagag   4380

gaaatacaga gagaacctct tccactttta cttttcgtcc aaataaaatg catggtgtac   4440

cagaagttga agatcgggtt gaggattggg gctagctcga tgacactaag gccccaacat   4500

cgcgggacct gctgtggcgc ggattcttag gaacgctgtt ctagccggcc ccctctccag   4560

gggtcgccgt ggccggcatt atttcctagt tcttcttgta accctgaggt gccagcgcgg   4620

ggagtgagga ggggtcaggg ggctaaggat gcaacctctg acgttctgcg ccttcctagg   4680

agagtcttac atgtgttgag atttcacaag caatgcgagt tgtaaaatac cagctctaca   4740

agaagctagg ctctgtgacg gcatagtttt cagtagcttt atcacaatat tcacaatgga   4800

gaattatatg acatggtagc agaaataggc ccttttatgt gttgcttcta ttttacctca   4860

aattgtagat atagggtaat caataaaatc catccatgcc tttcacacac taagt        4915


<210>  5289
<211>  933
<212>  PRT
<213>  Homo sapiens

<400>  5289

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg Pro Lys Ala Asn Glu 
        275                 280                 285


Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn Ala Gly Lys Arg Lys 
    290                 295                 300


Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala Arg Ile Thr Asp Leu 
305                 310                 315                 320


Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys Tyr Ala Gln Ala Ile 
                325                 330                 335


Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro Leu Phe Gln Ser His 
            340                 345                 350


Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg 
        355                 360                 365


Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu Arg Ile Leu Leu Ala 
    370                 375                 380


Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His Glu Leu Leu Asn Ser 
385                 390                 395                 400


Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala Ser Gly Val Lys Glu 
                405                 410                 415


Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys Met Val Asp Gln Leu 
            420                 425                 430


Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser Thr Glu Ala Lys Ala 
        435                 440                 445


Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn Asp Leu Tyr Val Glu 
    450                 455                 460


Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro Ser Trp Tyr Gly Ile 
465                 470                 475                 480


Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn Arg Ile Lys Phe Val 
                485                 490                 495


Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr Thr Glu Val Thr Gln 
            500                 505                 510


Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly Leu Thr Glu Ala Val 
        515                 520                 525


Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Tyr Val 
    530                 535                 540


Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser Pro Thr Trp Phe Gly 
545                 550                 555                 560


Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser Asn Lys Ile Lys Phe 
                565                 570                 575


Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr Leu Pro Pro Gly Met 
            580                 585                 590


Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser Pro Lys Arg Pro Arg 
        595                 600                 605


Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile Glu Val Thr Val Glu 
    610                 615                 620


Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala Val Arg Thr Pro Thr 
625                 630                 635                 640


Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro Arg Gly Arg Glu Phe 
                645                 650                 655


Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp Leu Lys Gln Lys Val 
            660                 665                 670


Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala Leu Gly Leu Lys Gln 
        675                 680                 685


Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser Phe Pro Glu Asp Phe 
    690                 695                 700


Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe Arg Arg Pro Ser Thr 
705                 710                 715                 720


Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg Asn Lys Ala Lys Ile 
                725                 730                 735


Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu Thr Ala Ile Lys Glu 
            740                 745                 750


Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile Asn Ser Ser Pro Asn 
        755                 760                 765


Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu Asn Ile Ile Gln Val 
    770                 775                 780


Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser Lys Val Glu Lys Ala 
785                 790                 795                 800


Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe Ser Arg Lys Phe Gly 
                805                 810                 815


Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val Pro Tyr Arg Lys Ile 
            820                 825                 830


Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly Met Pro Pro Gly Val 
        835                 840                 845


Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser Ser Met Arg Arg Ile 
    850                 855                 860


Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val Ile Arg Pro Phe Pro 
865                 870                 875                 880


Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln Ser Glu Ser Glu Gly 
                885                 890                 895


Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln Leu Glu Val Pro Ala 
            900                 905                 910


Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser Gln Ile Lys Gln Glu 
        915                 920                 925


Pro Asp Pro Thr Trp 
    930


<210>  5290
<211>  4063
<212>  DNA
<213>  Homo sapiens

<400>  5290
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1920

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   1980

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2040

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2100

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2160

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2220

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2280

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2340

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2400

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2460

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2520

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2580

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2640

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2700

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2760

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2820

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2880

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   2940

attcacggtc attagaccat ttccaggact tgtgattaat aaccagctgg ttgatcagag   3000

tgagtcagaa ggccccgtga tacaagaatc agctgaacca agccagttgg aagttccagc   3060

cacagaagaa ataaaagaga ctgatggaag ctctcagatc aagcaagaac cagaccccac   3120

gtggtagacc tcttccctcc taggcttaaa gtatcagtgg ttgagaagag cttttcggac   3180

ctgttactac cccaagctgt agccttgagt tacggtgttt attttccaat caagtgaaga   3240

tatctcctac ttctcctact ggaacatctc agcttctgca gtgaagaaaa attcctgtga   3300

tagttcagtt ctttagtttt tctatttgaa aaaaaaaaat catttaaatg atcctttgtt   3360

cacggctctc cttaatgact gagtgaacag ttcctatctg tatatttgac taaacctttt   3420

cctaagctat ctctcatggt tcctatgttt ttttatcata attaaaagca aaaccatctg   3480

gatcacctaa cagtcagagg tcagtatctc agcgtgtgaa ttatagagga aatacagaga   3540

gaacctcttc cacttttact tttcgtccaa ataaaatgca tggtgtacca gaagttgaag   3600

atcgggttga ggattggggc tagctcgatg acactaaggc cccaacatcg cgggacctgc   3660

tgtggcgcgg attcttagga acgctgttct agccggcccc ctctccaggg gtcgccgtgg   3720

ccggcattat ttcctagttc ttcttgtaac cctgaggtgc cagcgcgggg agtgaggagg   3780

ggtcaggggg ctaaggatgc aacctctgac gttctgcgcc ttcctaggag agtcttacat   3840

gtgttgagat ttcacaagca atgcgagttg taaaatacca gctctacaag aagctaggct   3900

ctgtgacggc atagttttca gtagctttat cacaatattc acaatggaga attatatgac   3960

atggtagcag aaataggccc ttttatgtgt tgcttctatt ttacctcaaa ttgtagatat   4020

agggtaatca ataaaatcca tccatgcctt tcacacacta agt                     4063


<210>  5291
<211>  605
<212>  PRT
<213>  Homo sapiens

<400>  5291

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val Lys Glu Asp Trp 
    530                 535                 540


Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu Glu Ile Phe Asn 
545                 550                 555                 560


Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala Val Lys Val Pro 
                565                 570                 575


Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys Gly Ser Ser Ala 
            580                 585                 590


Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu Asn 
        595                 600                 605


<210>  5292
<211>  3734
<212>  DNA
<213>  Homo sapiens

<400>  5292
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1080

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1140

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1200

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1260

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1320

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1380

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1440

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1500

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1560

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1620

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1680

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1740

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1800

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1860

gaacgaatac accagctcaa gctcttggac tcaccgaggc agtaaaagta ccatatcctg   1920

tgtttgaatc aaacccggag ttcttgtatg tggaaggctt gccagagggg attcccttcc   1980

gaagccctac ctggtttgga attccacgac ttgaaaggat cgtccgcggg agtaataaaa   2040

tcaagttcgt tgttaaaaaa cctgaactag ttatttccta cttgcctcct gggatggcta   2100

gtaaaataaa cactaaagct ttgcagtccc ccaaaagacc acgaagtcct gggagtaatt   2160

caaaggttcc tgaaattgag gtcaccgtgg aaggccctaa taacaacaat cctcaaacct   2220

cagctgttcg aaccccgacc cagactaacg gttctaacgt tcccttcaag ccacgaggga   2280

gagagttttc ctttgaggcc tggaatgcca aaatcacgga cctaaaacag aaagttgaaa   2340

atctcttcaa tgagaaatgt ggggaagctc ttggccttaa acaagctgtg aaggtgccgt   2400

tcgcgttatt tgagtctttc ccggaagact tttatgtgga aggcttacct gagggtgtgc   2460

cattccgaag accatcgact tttggcattc cgaggctgga gaagatactc agaaacaaag   2520

ccaaaattaa gttcatcatt aaaaagcccg aaatgtttga gacggcgatt aaggagagca   2580

cctcctctaa gagccctccc agaaaaataa attcatcacc caatgttaat actactgcat   2640

caggtgttga agaccttaac atcattcagg tgacaattcc agatgatgat aatgaaagac   2700

tctcgaaagt tgaaaaagct agacagctaa gagaacaagt gaatgacctc tttagtcgga   2760

aatttggtga agctattggt atgggttttc ctgtgaaagt tccctacagg aaaatcacaa   2820

ttaaccctgg ctgtgtggtg gttgatggca tgcccccggg ggtgtccttc aaagccccca   2880

gctacctgga aatcagctcc atgagaagga tcttagactc tgccgagttt atcaaattca   2940

cggtcattag accatttcca ggacttgtga ttaataacca gctggttgat cagagtgagt   3000

cagaaggccc cgtgatacaa gaatcagctg aaccaagcca gttggaagtt ccagccacag   3060

aagaaataaa agagactgat ggaagctctc agatcaagca agaaccagac cccacgtggt   3120

agacctcttc cctcctaggc aaaaccatct ggatcaccta acagtcagag gtcagtatct   3180

cagcgtgtga attatagagg aaatacagag agaacctctt ccacttttac ttttcgtcca   3240

aataaaatgc atggtgtacc agaagttgaa gatcgggttg aggattgggg ctagctcgat   3300

gacactaagg ccccaacatc gcgggacctg ctgtggcgcg gattcttagg aacgctgttc   3360

tagccggccc cctctccagg ggtcgccgtg gccggcatta tttcctagtt cttcttgtaa   3420

ccctgaggtg ccagcgcggg gagtgaggag gggtcagggg gctaaggatg caacctctga   3480

cgttctgcgc cttcctagga gagtcttaca tgtgttgaga tttcacaagc aatgcgagtt   3540

gtaaaatacc agctctacaa gaagctaggc tctgtgacgg catagttttc agtagcttta   3600

tcacaatatt cacaatggag aattatatga catggtagca gaaataggcc cttttatgtg   3660

ttgcttctat tttacctcaa attgtagata tagggtaatc aataaaatcc atccatgcct   3720

ttcacacact aagt                                                     3734


<210>  5293
<211>  954
<212>  PRT
<213>  Homo sapiens

<400>  5293

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Gly Ser 
                245                 250                 255


His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met Glu Val Pro Ala 
            260                 265                 270


Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser Glu Asp Pro Glu 
        275                 280                 285


Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro Pro Ser Lys Arg 
    290                 295                 300


Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro Glu Pro Ala Asn 
305                 310                 315                 320


Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu Lys Trp Asn Ala 
                325                 330                 335


Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu Phe Glu Arg Lys 
            340                 345                 350


Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr Ile Pro Tyr Pro 
        355                 360                 365


Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu Gly Leu Pro Glu 
    370                 375                 380


Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile Pro Arg Leu Glu 
385                 390                 395                 400


Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val Ile Lys Lys His 
                405                 410                 415


Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu Asp Lys Pro Ala 
            420                 425                 430


Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr Lys Leu Arg Lys 
        435                 440                 445


Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu Ala Leu Gly Ser 
    450                 455                 460


Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu Ala His Pro Asn 
465                 470                 475                 480


Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro Phe Arg Ser Pro 
                485                 490                 495


Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile Gln Val Gly Asn 
            500                 505                 510


Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu Thr His Ser Thr 
        515                 520                 525


Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Ala Gln Ala Leu Gly 
    530                 535                 540


Leu Thr Glu Ala Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro 
545                 550                 555                 560


Glu Phe Leu Tyr Val Glu Gly Leu Pro Glu Gly Ile Pro Phe Arg Ser 
                565                 570                 575


Pro Thr Trp Phe Gly Ile Pro Arg Leu Glu Arg Ile Val Arg Gly Ser 
            580                 585                 590


Asn Lys Ile Lys Phe Val Val Lys Lys Pro Glu Leu Val Ile Ser Tyr 
        595                 600                 605


Leu Pro Pro Gly Met Ala Ser Lys Ile Asn Thr Lys Ala Leu Gln Ser 
    610                 615                 620


Pro Lys Arg Pro Arg Ser Pro Gly Ser Asn Ser Lys Val Pro Glu Ile 
625                 630                 635                 640


Glu Val Thr Val Glu Gly Pro Asn Asn Asn Asn Pro Gln Thr Ser Ala 
                645                 650                 655


Val Arg Thr Pro Thr Gln Thr Asn Gly Ser Asn Val Pro Phe Lys Pro 
            660                 665                 670


Arg Gly Arg Glu Phe Ser Phe Glu Ala Trp Asn Ala Lys Ile Thr Asp 
        675                 680                 685


Leu Lys Gln Lys Val Glu Asn Leu Phe Asn Glu Lys Cys Gly Glu Ala 
    690                 695                 700


Leu Gly Leu Lys Gln Ala Val Lys Val Pro Phe Ala Leu Phe Glu Ser 
705                 710                 715                 720


Phe Pro Glu Asp Phe Tyr Val Glu Gly Leu Pro Glu Gly Val Pro Phe 
                725                 730                 735


Arg Arg Pro Ser Thr Phe Gly Ile Pro Arg Leu Glu Lys Ile Leu Arg 
            740                 745                 750


Asn Lys Ala Lys Ile Lys Phe Ile Ile Lys Lys Pro Glu Met Phe Glu 
        755                 760                 765


Thr Ala Ile Lys Glu Ser Thr Ser Ser Lys Ser Pro Pro Arg Lys Ile 
    770                 775                 780


Asn Ser Ser Pro Asn Val Asn Thr Thr Ala Ser Gly Val Glu Asp Leu 
785                 790                 795                 800


Asn Ile Ile Gln Val Thr Ile Pro Asp Asp Asp Asn Glu Arg Leu Ser 
                805                 810                 815


Lys Val Glu Lys Ala Arg Gln Leu Arg Glu Gln Val Asn Asp Leu Phe 
            820                 825                 830


Ser Arg Lys Phe Gly Glu Ala Ile Gly Met Gly Phe Pro Val Lys Val 
        835                 840                 845


Pro Tyr Arg Lys Ile Thr Ile Asn Pro Gly Cys Val Val Val Asp Gly 
    850                 855                 860


Met Pro Pro Gly Val Ser Phe Lys Ala Pro Ser Tyr Leu Glu Ile Ser 
865                 870                 875                 880


Ser Met Arg Arg Ile Leu Asp Ser Ala Glu Phe Ile Lys Phe Thr Val 
                885                 890                 895


Ile Arg Pro Phe Pro Gly Leu Val Ile Asn Asn Gln Leu Val Asp Gln 
            900                 905                 910


Ser Glu Ser Glu Gly Pro Val Ile Gln Glu Ser Ala Glu Pro Ser Gln 
        915                 920                 925


Leu Glu Val Pro Ala Thr Glu Glu Ile Lys Glu Thr Asp Gly Ser Ser 
    930                 935                 940


Gln Ile Lys Gln Glu Pro Asp Pro Thr Trp 
945                 950


<210>  5294
<211>  7804
<212>  DNA
<213>  Homo sapiens

<400>  5294
gggtcttgtt ctgtctccca agctggagtg cagtggtgtg gtcataggtc actgcagcgt     60

cgaactccta ggctcaagtg atcctcttgc ctcaggctcc tgagtagctg ggacaacagg    120

cgtgtaccac acctggatac tttttaaatt tttggtagag aagggatctc actctattgc    180

caagctggtg tcgaactctt ggtcttaagc agccctccca cgtcagcatc ccaaagtgtt    240

gggatttcag agggatcatg gcccaagttg caatgtccac cctccccgtt gaagatgagg    300

agtcctcgga gagcaggatg gtggtgacat tcctcatgtc agctctcgag tccatgtgta    360

aagaactggc caagtccaaa gccgaagtgg cctgcattgc agtgtatgaa acagacgtgt    420

ttgtcgtcgg aactgaaaga ggacgtgctt ttgtcaatac cagaaaggat tttcaaaaag    480

attttgtaaa atattgtgtt gaagaagaag aaaaagctgc agagatgcat aaaatgaaat    540

ctacaaccca ggcaaatcgg atgagtgtag atgctgtaga aattgaaaca ctcagaaaaa    600

cagttgagga ctatttctgc ttttgctatg ggaaagcttt aggcaaatcc acagtggtac    660

ctgtaccata tgagaagatg ctgcgagacc agtcggctgt ggtagtgcag gggcttccgg    720

aaggtgttgc ctttaaacac cccgagaact atgatcttgc aaccctgaaa tggattttgg    780

agaacaaagc agggatttca ttcatcatta agagaccttt tttagagcca aagaagcatg    840

taggtggtcg tgtgatggta acagatgctg acaggtcaat actatctcca ggtggaagtt    900

gtggccccat caaagtgaaa actgaaccca cagaagattc tggcatttcc ctggaaatgg    960

cagctgtgac agtaaaggaa gaatcagaag atcctgatta ttatcaatat aacattcaag   1020

caggcccttc tgaaactgat gatgttgatg aaaaacagcc cctatcgaag cctttgcaag   1080

gaagccacca ttcttcagag ggcaatgaag gcacagaaat ggaagtacca gcagaagatt   1140

ctactcaaca tgtcccttca gaaacaagtg aggaccctga agttgaggtg actattgaag   1200

atgatgatta ttctccaccg tctaagagac caaaggccaa tgagctaccg cagccaccag   1260

tcccggaacc cgccaatgct gggaagcgga aagtgaggga gttcaacttc gagaaatgga   1320

atgctcgcat cactgatcta cgtaaacaag ttgaagaatt gtttgaaagg aaatatgctc   1380

aagccataaa agccaaaggt ccggtgacga tcccgtaccc tcttttccag tctcatgttg   1440

aagatcttta tgtagaagga cttcctgaag gaattccttt tagaaggcca tctacttacg   1500

gaattcctcg cctggagagg atattacttg caaaggaaag gattcgtttt gtgattaaga   1560

aacatgagct tctgaattca acacgtgaag atttacagct tgataagcca gcttcaggag   1620

taaaggaaga atggtatgcc agaatcacta aattaagaaa gatggtggat cagcttttct   1680

gcaaaaaatt tgcggaagcc ttggggagca ctgaagccaa ggctgtaccg taccaaaaat   1740

ttgaggcaca cccgaatgat ctgtacgtgg aaggactgcc agaaaacatt cctttccgaa   1800

gtccctcatg gtatggaatc ccaaggctgg aaaaaatcat tcaagtgggc aatcgaatta   1860

aatttgttat taaaagacca gaacttctga ctcacagtac cactgaagtt actcagccaa   1920

gaacgaatac accagtcaaa gaagattgga atgtcagaat taccaagcta cggaagcaag   1980

tggaagagat ttttaatttg aaatttgctc aagctcttgg actcaccgag gcagtaaaag   2040

taccatatcc tgtgtttgaa tcaaacccgg agttcttgaa aggatcgtcc gcgggagtaa   2100

taaaatcaag ttcgttgtta aaaaacctga actagttatt tcctacttgc ctcctgggat   2160

ggctagtaaa ataaacacta aagctttgca gtcccccaaa agaccacgaa gtcctgggag   2220

taattcaaag gttcctgaaa ttgaggtcac cgtggaaggc cctaataaca acaatcctca   2280

aacctcagct gttcgaaccc cgacccagac taacggttct aacgttccct tcaagccacg   2340

agggagagag ttttcctttg aggcctggaa tgccaaaatc acggacctaa aacagaaagt   2400

tgaaaatctc ttcaatgaga aatgtgggga agctcttggc cttaaacaag ctgtgaaggt   2460

gccgttcgcg ttatttgagt ctttcccgga agacttttat gtggaaggct tacctgaggg   2520

tgtgccattc cgaagaccat cgacttttgg cattccgagg ctggagaaga tactcagaaa   2580

caaagccaaa attaagttca tcattaaaaa gcccgaaatg tttgagacgg cgattaagga   2640

gagcacctcc tctaagagcc ctcccagaaa aataaattca tcacccaatg ttaatactac   2700

tgcatcaggt gttgaagacc ttaacatcat tcaggtgaca attccagatg atgataatga   2760

aagactctcg aaagttgaaa aagctagaca gctaagagaa caagtgaatg acctctttag   2820

tcggaaattt ggtgaagcta ttggtatggg ttttcctgtg aaagttccct acaggaaaat   2880

cacaattaac cctggctgtg tggtggttga tggcatgccc ccgggggtgt ccttcaaagc   2940

ccccagctac ctggaaatca gctccatgag aaggatctta gactctgccg agtttatcaa   3000

attcacggtc attaggtaag tgagagtttc ctgcttagtc acaggagcga atctggagct   3060

catgaggctg actcttctaa aatgcagcca caggtagtca tcgaatccgg cttcctatgc   3120

tgtgcaatca acaaatcaaa ataacttgtg tcatcattag aatgtcagat gtgcttctac   3180

gaactaagct gactctttta attctttggc aaagggttgg caaactagga ctgtttgcca   3240

aattcaggct gcctcctatt tttagagtct tcctgaaaca cagctacacc cgtattatcc   3300

atggctgctt tcctgtcaca gtgagtaagt agctgggact gagaaggcat ggcctccaaa   3360

gtctaaaata tttactctct agcactttgt agaaaaacct tagctaggca cagtggctaa   3420

cgcctgtaat cccagcattt tgggaggcca aggcaggcag atcacctgag gtcaggagtt   3480

ccagaccagc ctggccaaca tggtgaaatc ccatctctac aaaaataaaa cagttagctg   3540

ggcatgatgg cgggtgcctg taatcccagc tactcgggag gctgaggcag gatagtcgct   3600

tgaacccagg aggtggaggt tgcaatgagc caagatcatg ccactgcact ccagcctgga   3660

cgacagagtg agactccatc acaagaaaaa aagaactttg tcaacctctg tcttagggcg   3720

ccttgtcaca ggcttcgggt cagacggatt caaccttgca tcagccattt gttagccagg   3780

tcactctgtt ctttgtctgt aaatgagatt gatcgttgtt cccactgaga gtgtcagctc   3840

cttcccgtag agcaggcatg atgattgtac tcacctctga caccattgtg agtgccacat   3900

tccttcccac gtccttgtca ctgtaagaga tgcccacctg agcaccaacc ccaggttatc   3960

ttcccctttg tcttccagcc ccccagaaac agctacgact caacctaccc aatcatttca   4020

tcatcagatt gccactgtct ctagttcagg tctcttggga ctggcactca gaaatctcat   4080

aataaatcct cttgaggctt ctcatacact cgtcttcttc caatcttctt tccctcaaaa   4140

tctcatattt tggttccact tcacccaccg tcattctcca tatcactccc aggagttagg   4200

caaaaagccc cttccgttct tccgtatgtt aaacttagaa tcactctgtt ccctgctctg   4260

cgtttctatt ttttgttttt cctccattta ctagtagctt aacactttct aacagtgttc   4320

ttattattga tacgtatcta tctcttccat aagcttataa ggtcacggat aatacttctc   4380

attgtagtac gtaaatgacg tgggctagat atgagttgaa taaacagtta tacctgtaaa   4440

ttcttacaga gtgaaaataa attgttatac tttacaattt gtttctctct ttagaccatt   4500

tccaggactt gtgattaata accgtgagta ttttgtgaag tgttttgttt ttgttttttc   4560

ctggggtctg acgtgtgtgc gtgtgagtgt gtatacatgc ttaacgtata tcacgttact   4620

tcacctatgt cagtaaccag gccaaatact tgttttagcc ctcagtaaaa acaccaggca   4680

cttcctagtt gtaaaattat tcaagcttct taacttccta tcctcgatgc acttaatcat   4740

aaaatggtaa taatagcacc gattttgggg gagtcgttcc agtagatgga aagcatctgg   4800

aacaggtgtc agcaagctcc tgccgacgtg tatgcataaa gttttattga aaccaccatc   4860

gtgtccattt gtttatggca gaactgagag atggcagcag caagtgtgtg cctgcaaaac   4920

ctaaaatatt tactaattgg ctctgcaaga aaagagtttg catcccccta acctagaaca   4980

gtgtctagcc tctagtatgt gtttagccta cagtatgtgc tcagcgaata caatctatat   5040

ttattactgc ttttatgact gttataatta ctgtgcttgg atttcgttac aaagtaagtc   5100

acaatgtgcc tgcttctgtt agtatttcag cacagtgcct ggcacacatg gggctctcaa   5160

atattgctga gcgagtgaac aaatgtcctt tcaattcctt aacgttgatg tcattttcaa   5220

tagtattttg agccaaactt aattttgcga gtgtgttttg ttttcttaac tttattatta   5280

aaaatgtata aaagtgaggc caggcgtggt ggctcacgcc tgtaatccca gcagtttggg   5340

aggctgaggc aggcggatca gttgaggttg ggagttggag accagcccgt ccaacatggt   5400

gaaagcctgt ctctactaaa aatacaaaaa tcagctgggt gtggtggcgc gtgcctgtaa   5460

tcccagctac tcaggaggct gaggcaggag agttgcttga atcctagagg tggaggttgc   5520

agtgagctga gatcgtgcca ttgcactcca gcctgggcaa caagagcaaa actctgtccc   5580

aataaataaa taaataaaat gttctctttt gttcctgttc ttgtgcggta gtgtggtata   5640

gagttttatg gtaattactg tgaattagtg attctgaggg acatatcaga actctgaggt   5700

ttgtttcctt ctcatcttga gggaaacagc aaatgtatgt taaaatgctt ttccaaggga   5760

acaacacatc cttacattat ttaaaccaat ctgcttcatt ttcagagctg gttgatcaga   5820

gtgagtcaga aggccccgtg atacaagaat cagctgaacc aagccagttg gaagttccag   5880

ccacagaaga aataaaagag actgatggaa gctctcagat caagcaagaa ccagacccca   5940

cgtggtagac ctcttccctc ctagggtaaa tcagcttctg tgtcagggat gctgtgtggt   6000

gtccatctga accccctgca tacgcgtagc taatgtgatc tccccacttt cacataagat   6060

ggtggccctg ccttcaggga atgtgggagc caggtgggag ccttcccgga tatttaagct   6120

agaagattct acagggagat tctccttgga tcaatatatg tctctcagtc aaagatgtaa   6180

aagcactttt gccttaaaaa gaatgttctg tttctaaata gagtcaacgt tgtcctcctc   6240

attggaattc actatgagtc agaatcatta gactgacttt tttttttcca tagtaatagt   6300

attttgcaga gtctcacaga gctgcagatc ttttgttcat cttgcagagt taacaagtct   6360

gatcctgtta gtccagattt cttaaatttg gccaagttat aataggagca gtagcttgag   6420

acccgaagtc aggaaacttt gacaatggat tttttttttt aatccagaga cttgtactgg   6480

aatttgcctt accctgtcag ctcatggact taaggtttca tcccgcttta tgagtgcttc   6540

tgaatccaag tcattgttac ctgaatttgc aaattaagtt gtgatattcg tgactgttaa   6600

attcctgtaa ttagattaac ctctttgctt gcttgtttgt tttctctcct attttagctt   6660

aaagtatcag tggttgagaa gagcttttcg gacctgttac taccccaagc tgtgtaatat   6720

acttgtataa cagaaatacc ttctatacaa accttttttt ctacttttag atagaaatgt   6780

ctactttttc agcagttctg tgaattaaag agcagagtga ctgtgggtct ggaatggctg   6840

gtgtacttgg gaatgtacta tcaggatttt acagcaatgc tgggaaatga cagggaaaat   6900

gacaggaatg aatctcacca gattttttat gtactcagca gagccttgag ttacggtgtt   6960

tattttccaa tcaagtgaag atatctccta cttctcctac tggaacatct cagcttctgc   7020

agtgaagaaa aattcctgtg atagttcagt tctttagttt ttctatttga aaaaaaaaaa   7080

tcatttaaat gatcctttgt tcacggctct ccttaatgac tgagtgaaca gttcctatct   7140

gtatatttga ctaaaccttt tcctaagcta tctctcatgg ttcctatgtt tttttatcat   7200

aattaaaagc aaaaccatct ggatcaccta acagtcagag gtcagtatct cagcgtgtga   7260

attatagagg aaatacagag agaacctctt ccacttttac ttttcgtcca aataaaatgc   7320

atggtgtacc agaagttgaa gatcgggttg aggattgggg ctagctcgat gacactaagg   7380

ccccaacatc gcgggacctg ctgtggcgcg gattcttagg aacgctgttc tagccggccc   7440

cctctccagg ggtcgccgtg gccggcatta tttcctagtt cttcttgtaa ccctgaggtg   7500

ccagcgcggg gagtgaggag gggtcagggg gctaaggatg caacctctga cgttctgcgc   7560

cttcctagga gagtcttaca tgtgttgaga tttcacaagc aatgcgagtt gtaaaatacc   7620

agctctacaa gaagctaggc tctgtgacgg catagttttc agtagcttta tcacaatatt   7680

cacaatggag aattatatga catggtagca gaaataggcc cttttatgtg ttgcttctat   7740

tttacctcaa attgtagata tagggtaatc aataaaatcc atccatgcct ttcacacact   7800

aagt                                                                7804


<210>  5295
<211>  625
<212>  PRT
<213>  Homo sapiens

<400>  5295

Met Ala Gln Val Ala Met Ser Thr Leu Pro Val Glu Asp Glu Glu Ser 
1               5                   10                  15


Ser Glu Ser Arg Met Val Val Thr Phe Leu Met Ser Ala Leu Glu Ser 
            20                  25                  30


Met Cys Lys Glu Leu Ala Lys Ser Lys Ala Glu Val Ala Cys Ile Ala 
        35                  40                  45


Val Tyr Glu Thr Asp Val Phe Val Val Gly Thr Glu Arg Gly Arg Ala 
    50                  55                  60


Phe Val Asn Thr Arg Lys Asp Phe Gln Lys Asp Phe Val Lys Tyr Cys 
65                  70                  75                  80


Val Glu Glu Glu Glu Lys Ala Ala Glu Met His Lys Met Lys Ser Thr 
                85                  90                  95


Thr Gln Ala Asn Arg Met Ser Val Asp Ala Val Glu Ile Glu Thr Leu 
            100                 105                 110


Arg Lys Thr Val Glu Asp Tyr Phe Cys Phe Cys Tyr Gly Lys Ala Leu 
        115                 120                 125


Gly Lys Ser Thr Val Val Pro Val Pro Tyr Glu Lys Met Leu Arg Asp 
    130                 135                 140


Gln Ser Ala Val Val Val Gln Gly Leu Pro Glu Gly Val Ala Phe Lys 
145                 150                 155                 160


His Pro Glu Asn Tyr Asp Leu Ala Thr Leu Lys Trp Ile Leu Glu Asn 
                165                 170                 175


Lys Ala Gly Ile Ser Phe Ile Ile Lys Arg Pro Phe Leu Glu Pro Lys 
            180                 185                 190


Lys His Val Gly Gly Arg Val Met Val Thr Asp Ala Asp Arg Ser Ile 
        195                 200                 205


Leu Ser Pro Gly Gly Ser Cys Gly Pro Ile Lys Val Lys Thr Glu Pro 
    210                 215                 220


Thr Glu Asp Ser Gly Ile Ser Leu Glu Met Ala Ala Val Thr Val Lys 
225                 230                 235                 240


Glu Glu Ser Glu Asp Pro Asp Tyr Tyr Gln Tyr Asn Ile Gln Ala Gly 
                245                 250                 255


Pro Ser Glu Thr Asp Asp Val Asp Glu Lys Gln Pro Leu Ser Lys Pro 
            260                 265                 270


Leu Gln Gly Ser His His Ser Ser Glu Gly Asn Glu Gly Thr Glu Met 
        275                 280                 285


Glu Val Pro Ala Glu Asp Ser Thr Gln His Val Pro Ser Glu Thr Ser 
    290                 295                 300


Glu Asp Pro Glu Val Glu Val Thr Ile Glu Asp Asp Asp Tyr Ser Pro 
305                 310                 315                 320


Pro Ser Lys Arg Pro Lys Ala Asn Glu Leu Pro Gln Pro Pro Val Pro 
                325                 330                 335


Glu Pro Ala Asn Ala Gly Lys Arg Lys Val Arg Glu Phe Asn Phe Glu 
            340                 345                 350


Lys Trp Asn Ala Arg Ile Thr Asp Leu Arg Lys Gln Val Glu Glu Leu 
        355                 360                 365


Phe Glu Arg Lys Tyr Ala Gln Ala Ile Lys Ala Lys Gly Pro Val Thr 
    370                 375                 380


Ile Pro Tyr Pro Leu Phe Gln Ser His Val Glu Asp Leu Tyr Val Glu 
385                 390                 395                 400


Gly Leu Pro Glu Gly Ile Pro Phe Arg Arg Pro Ser Thr Tyr Gly Ile 
                405                 410                 415


Pro Arg Leu Glu Arg Ile Leu Leu Ala Lys Glu Arg Ile Arg Phe Val 
            420                 425                 430


Ile Lys Lys His Glu Leu Leu Asn Ser Thr Arg Glu Asp Leu Gln Leu 
        435                 440                 445


Asp Lys Pro Ala Ser Gly Val Lys Glu Glu Trp Tyr Ala Arg Ile Thr 
    450                 455                 460


Lys Leu Arg Lys Met Val Asp Gln Leu Phe Cys Lys Lys Phe Ala Glu 
465                 470                 475                 480


Ala Leu Gly Ser Thr Glu Ala Lys Ala Val Pro Tyr Gln Lys Phe Glu 
                485                 490                 495


Ala His Pro Asn Asp Leu Tyr Val Glu Gly Leu Pro Glu Asn Ile Pro 
            500                 505                 510


Phe Arg Ser Pro Ser Trp Tyr Gly Ile Pro Arg Leu Glu Lys Ile Ile 
        515                 520                 525


Gln Val Gly Asn Arg Ile Lys Phe Val Ile Lys Arg Pro Glu Leu Leu 
    530                 535                 540


Thr His Ser Thr Thr Glu Val Thr Gln Pro Arg Thr Asn Thr Pro Val 
545                 550                 555                 560


Lys Glu Asp Trp Asn Val Arg Ile Thr Lys Leu Arg Lys Gln Val Glu 
                565                 570                 575


Glu Ile Phe Asn Leu Lys Phe Ala Gln Ala Leu Gly Leu Thr Glu Ala 
            580                 585                 590


Val Lys Val Pro Tyr Pro Val Phe Glu Ser Asn Pro Glu Phe Leu Lys 
        595                 600                 605


Gly Ser Ser Ala Gly Val Ile Lys Ser Ser Ser Leu Leu Lys Asn Leu 
    610                 615                 620


Asn 
625


<210>  5296
<211>  1307
<212>  DNA
<213>  Homo sapiens

<400>  5296
gccccgcccg gggtgctcag aggtcggagt atcgctggga ggagagttgg ttcatttgga     60

ggagggaatg cgactctgag cgggccaagc cctagtgggt cagagtagga ttctgatgga    120

atttgcggtc tcaccgccta ctagggagga aaagcagttt tcaggagtcc cgcaccgccg    180

ccagccgtgg gctgggacta caagtcacgg tctgtggagt ccaggagtgg gggcgggcgg    240

gaggcaggct gggagctgta gtagtgtcac cgccacgttc gcagcaggta gatgctcatc    300

ttgctaacgg attggtgaga gtggacagca attaggcttt ggcaccttgg agcgtggctc    360

cagctaaggg aagcgaaacg cttcctgggt gagaggactt ttattctttg ctcatcctct    420

taaacctggc gagtgagcgc ctgaggttcg gagtgccttc ttcacagacg acgcgaatgt    480

ggggtcttcg tgtttgccga actgaaggga atttgccttc ctgcctttag agctaaggtc    540

ttgctctatc tcccatgcca aagtgcagtg ctatgatcac ggctcgctgc agccttgaac    600

tcctgggctc aaggcatcct cctgcctcac tacgtcacca agcccagcta atacatttta    660

aaaatttatt atttatttat ttatttattt ttggtagaga agggggtctc accaggttgc    720

ccaggctgat ctcgaattcc tgtgcactag ggatcctcag cttccgaaag tgttgggatt    780

ttaggcgtga gccaccgcgc ctagcctata aatctttatt catctttgta aacttctatc    840

agagaatata ttctggtcta actcatcatt ttacaaataa agcgacttcc tgacatcccc    900

cagcgtattc ttagcagagc cgtaactaga agttatttta ctttcacaac agtggcctct    960

cacaatgtga cagaactgaa ggatttgatc catgaactga ctttcgtcat ttatacccac   1020

aaaccttttt ttacagagca gattggtcag cgaatttggt tataatagga aatatcagtg   1080

gtagaatact ttctcagatg aaagttagga gcactatgga atttagtgaa aaactcattg   1140

aagaaaatag gtgtaggccg ggcgcggtgg ctcacgcctg taatcccagc actttgggag   1200

gccgagatgg gaggatcacc tgaacccggg aggcggaggt tgcagtgagc tgtgatcaca   1260

ccattgcacc ccaacctggg cgacgggagt gaggccctgt ctcaaaa                 1307


<210>  5297
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5297

Met Pro Lys Cys Ser Ala Met Ile Thr Ala Arg Cys Ser Leu Glu Leu 
1               5                   10                  15


Leu Gly Ser Arg His Pro Pro Ala Ser Leu Arg His Gln Ala Gln Leu 
            20                  25                  30


Ile His Phe Lys Asn Leu Leu Phe Ile Tyr Leu Phe Ile Phe Gly Arg 
        35                  40                  45


Glu Gly Gly Leu Thr Arg Leu Pro Arg Leu Ile Ser Asn Ser Cys Ala 
    50                  55                  60


Leu Gly Ile Leu Ser Phe Arg Lys Cys Trp Asp Phe Arg Arg Glu Pro 
65                  70                  75                  80


Pro Arg Leu Ala Tyr Lys Ser Leu Phe Ile Phe Val Asn Phe Tyr Gln 
                85                  90                  95


Arg Ile Tyr Ser Gly Leu Thr His His Phe Thr Asn Lys Ala Thr Ser 
            100                 105                 110


<210>  5298
<211>  3412
<212>  DNA
<213>  Homo sapiens

<400>  5298
ggggagaggc ggctgcggct gcggctgcgg ctgctggcgg ggggtggggg ggaggaggaa     60

ccgggaaggg ggggcagggc gagcggagag ctagctgtgt tcctgaggcg gcgccgccgc    120

ctagggcggt ggggaggagg agggagccgc ggggcttggc ggggtcggga gggagggacg    180

tgctggggga acgagctggg gaagacggag cgggctctgt gccgggcggg cgggcggcgg    240

gggggccagc gaccgcagcc ggggggacgc gggaggatgg agcaagtgga gatcctgagg    300

aaattcatcc agagggtcca ggccatgaag agtcctgacc acaatgggga ggacaacttc    360

gcccgggact tcatgcggtt aagaagattg tctaccaaat atagaacaga aaagatatat    420

cccacagcca ctggagaaaa agaagaaaat gttaaaaaga acagatacaa ggacatactg    480

ccatttgatc acagccgagt taaattgaca ttaaagactc cttcacaaga ttcagactat    540

atcaatgcaa attttataaa gggcgtctat gggccaaaag catatgtagc aactcaagga    600

cctttagcaa atacagtaat agatttttgg aggatgatat gggagtataa tgttgtgatc    660

attgtaatgg cctgccgaga atttgagatg ggaaggaaaa aatgtgagcg ctattggcct    720

ttgtatggag aagaccccat aacgtttgca ccatttaaaa tttcttgtga ggatgaacaa    780

gcaagaacag actacttcat caggacactc ttacttgaat ttcaaaatga atctcgtagg    840

ctgtatcagt ttcattatgt gaactggcca gaccatgatg ttccttcatc atttgattct    900

attctggaca tgataagctt aatgaggaaa tatcaagaac atgaagatgt tcctatttgt    960

attcattgca gtgcaggctg tggaagaaca ggtgccattt gtgccataga ttatacgtgg   1020

aatttactaa aagctgggaa aataccagag gaatttaatg tatttaattt aatacaagaa   1080

atgagaacac aaaggcattc tgcagtacaa acaaaggagc aatatgaact tgttcataga   1140

gctattgccc aactgtttga aaaacagcta caactatatg aaattcatgg agctcagaaa   1200

attgctgatg gagtgaatga aattaacact gaaaacatgg tcagctccat agagcctgaa   1260

aaacaagatt ctcctcctcc aaaaccacca aggacccgca gttgccttgt tgaaggggat   1320

gctaaagaag aaatactgca gccaccggaa cctcatccag tgccacccat cttgacacct   1380

tctccccctt cagcttttcc aacagtcact actgtgtggc aggacaatga tagataccat   1440

ccaaagccag tgttgcatat ggtttcatca gaacaacatt cagcagacct caacagaaac   1500

tatagtaaat caacagaact tccagggaaa aatgaatcaa caattgaaca gatagataaa   1560

aaattggaac gaaatttaag ttttgagatt aagaaggtcc ctctccaaga gggaccaaaa   1620

agttttgatg ggaacacact tttgaatagg ggacatgcaa ttaaaattaa atctgcttca   1680

ccttgtatag ctgataaaat ctctaagcca caggaattaa gttcagatct aaatgtcggt   1740

gatacttccc agaattcttg tgtggactgc agtgtaacac aatcaaacaa agtttcagtt   1800

actccaccag aagaatccca gaattcagac acacctccaa ggccagaccg cttgcctctt   1860

gatgagaaag gacatgtaac gtggtcattt catggacctg aaaatgccat acccatacct   1920

gatttatctg aaggcaattc ctcagatatc aactatcaaa ctaggaaaac tgtgagttta   1980

acaccaagtc ctacaacaca agttgaaaca cctgatcttg tggatcatga taacacttca   2040

ccactcttca gaacacccct cagttttact aatccacttc actctgatga ctcagactca   2100

gatgaaagaa actctgatgg tgctgtgacc cagaataaaa ctaatatttc aacagcaagt   2160

gccacagttt ctgctgccac tagtactgaa agcatttcta ctaggaaagt attgccaatg   2220

tccattgcta gacataatat agcaggaaca acacattcag gtgctgaaaa agatgttgat   2280

gttagtgaag attcacctcc tcccctacct gaaagaactc ctgaatcgtt tgtgttagca   2340

agtgaacata atacacctgt aagatcggaa tggagtgaac ttcaaagtca ggaacgatct   2400

gaacaaaaaa agtctgaagg cttgataacc tctgaaaatg agaaatgtga tcatccagcg   2460

ggaggtattc actatgaaat gtgcatagaa tgtccaccta ctttcagtga caagagagaa   2520

caaatatcag aaaatccaac agaagccaca gatattggtt ttggtaatcg atgtggaaaa   2580

cccaaaggac caagagatcc accttcagaa tggacatgat tcagggagct agaagacact   2640

ttaagttata ctggaaaatt caggtgccac tgaaagccag atttatagta ttccatcttt   2700

aatatgtggg actaacagca gtgtagattg ttaccttaat attttttgct gggaccatct   2760

acctgcctta tactacactt aggaaaaagt attacatatg gtttattttg aaacttcaag   2820

tattattgcc ttaatgtctc ttaaccctgt tacacgctgc ttgtagacat gttaatatag   2880

taataccttt atgatatatt gagtttaagg actactcttt ttctgtttta tcatgtatgc   2940

attattttgt atatgtacag ggcaagtagg tatataattt gataaagttg caattgaaat   3000

attattaaca gaagatgtaa gaaatttctg catggtctaa atctttgtgt actttatttg   3060

taaattattt gccctggagt tttagaaaat agtttctgaa ttttaaactt gctggattca   3120

tgcagccagc tttgcaggtt atcagagatc aaagattgta ataataattt tgtaaattgt   3180

aagcaaaaag ttatttttat attatataca gtctaattgt tcatcctaat tgttcctgtt   3240

ttcatctagt cagagattca gtaagtgcct tggaacaata ttgaattctc ttagcttgtg   3300

tgtgtttctt taatatttga actcaagtgg gattagaaga ctatcaaaat acatgtatgt   3360

ttcaggatat ttgacctgtc attaaaaaaa acaaacagtt ttacagtgcc ta           3412


<210>  5299
<211>  780
<212>  PRT
<213>  Homo sapiens

<400>  5299

Met Glu Gln Val Glu Ile Leu Arg Lys Phe Ile Gln Arg Val Gln Ala 
1               5                   10                  15


Met Lys Ser Pro Asp His Asn Gly Glu Asp Asn Phe Ala Arg Asp Phe 
            20                  25                  30


Met Arg Leu Arg Arg Leu Ser Thr Lys Tyr Arg Thr Glu Lys Ile Tyr 
        35                  40                  45


Pro Thr Ala Thr Gly Glu Lys Glu Glu Asn Val Lys Lys Asn Arg Tyr 
    50                  55                  60


Lys Asp Ile Leu Pro Phe Asp His Ser Arg Val Lys Leu Thr Leu Lys 
65                  70                  75                  80


Thr Pro Ser Gln Asp Ser Asp Tyr Ile Asn Ala Asn Phe Ile Lys Gly 
                85                  90                  95


Val Tyr Gly Pro Lys Ala Tyr Val Ala Thr Gln Gly Pro Leu Ala Asn 
            100                 105                 110


Thr Val Ile Asp Phe Trp Arg Met Ile Trp Glu Tyr Asn Val Val Ile 
        115                 120                 125


Ile Val Met Ala Cys Arg Glu Phe Glu Met Gly Arg Lys Lys Cys Glu 
    130                 135                 140


Arg Tyr Trp Pro Leu Tyr Gly Glu Asp Pro Ile Thr Phe Ala Pro Phe 
145                 150                 155                 160


Lys Ile Ser Cys Glu Asp Glu Gln Ala Arg Thr Asp Tyr Phe Ile Arg 
                165                 170                 175


Thr Leu Leu Leu Glu Phe Gln Asn Glu Ser Arg Arg Leu Tyr Gln Phe 
            180                 185                 190


His Tyr Val Asn Trp Pro Asp His Asp Val Pro Ser Ser Phe Asp Ser 
        195                 200                 205


Ile Leu Asp Met Ile Ser Leu Met Arg Lys Tyr Gln Glu His Glu Asp 
    210                 215                 220


Val Pro Ile Cys Ile His Cys Ser Ala Gly Cys Gly Arg Thr Gly Ala 
225                 230                 235                 240


Ile Cys Ala Ile Asp Tyr Thr Trp Asn Leu Leu Lys Ala Gly Lys Ile 
                245                 250                 255


Pro Glu Glu Phe Asn Val Phe Asn Leu Ile Gln Glu Met Arg Thr Gln 
            260                 265                 270


Arg His Ser Ala Val Gln Thr Lys Glu Gln Tyr Glu Leu Val His Arg 
        275                 280                 285


Ala Ile Ala Gln Leu Phe Glu Lys Gln Leu Gln Leu Tyr Glu Ile His 
    290                 295                 300


Gly Ala Gln Lys Ile Ala Asp Gly Val Asn Glu Ile Asn Thr Glu Asn 
305                 310                 315                 320


Met Val Ser Ser Ile Glu Pro Glu Lys Gln Asp Ser Pro Pro Pro Lys 
                325                 330                 335


Pro Pro Arg Thr Arg Ser Cys Leu Val Glu Gly Asp Ala Lys Glu Glu 
            340                 345                 350


Ile Leu Gln Pro Pro Glu Pro His Pro Val Pro Pro Ile Leu Thr Pro 
        355                 360                 365


Ser Pro Pro Ser Ala Phe Pro Thr Val Thr Thr Val Trp Gln Asp Asn 
    370                 375                 380


Asp Arg Tyr His Pro Lys Pro Val Leu His Met Val Ser Ser Glu Gln 
385                 390                 395                 400


His Ser Ala Asp Leu Asn Arg Asn Tyr Ser Lys Ser Thr Glu Leu Pro 
                405                 410                 415


Gly Lys Asn Glu Ser Thr Ile Glu Gln Ile Asp Lys Lys Leu Glu Arg 
            420                 425                 430


Asn Leu Ser Phe Glu Ile Lys Lys Val Pro Leu Gln Glu Gly Pro Lys 
        435                 440                 445


Ser Phe Asp Gly Asn Thr Leu Leu Asn Arg Gly His Ala Ile Lys Ile 
    450                 455                 460


Lys Ser Ala Ser Pro Cys Ile Ala Asp Lys Ile Ser Lys Pro Gln Glu 
465                 470                 475                 480


Leu Ser Ser Asp Leu Asn Val Gly Asp Thr Ser Gln Asn Ser Cys Val 
                485                 490                 495


Asp Cys Ser Val Thr Gln Ser Asn Lys Val Ser Val Thr Pro Pro Glu 
            500                 505                 510


Glu Ser Gln Asn Ser Asp Thr Pro Pro Arg Pro Asp Arg Leu Pro Leu 
        515                 520                 525


Asp Glu Lys Gly His Val Thr Trp Ser Phe His Gly Pro Glu Asn Ala 
    530                 535                 540


Ile Pro Ile Pro Asp Leu Ser Glu Gly Asn Ser Ser Asp Ile Asn Tyr 
545                 550                 555                 560


Gln Thr Arg Lys Thr Val Ser Leu Thr Pro Ser Pro Thr Thr Gln Val 
                565                 570                 575


Glu Thr Pro Asp Leu Val Asp His Asp Asn Thr Ser Pro Leu Phe Arg 
            580                 585                 590


Thr Pro Leu Ser Phe Thr Asn Pro Leu His Ser Asp Asp Ser Asp Ser 
        595                 600                 605


Asp Glu Arg Asn Ser Asp Gly Ala Val Thr Gln Asn Lys Thr Asn Ile 
    610                 615                 620


Ser Thr Ala Ser Ala Thr Val Ser Ala Ala Thr Ser Thr Glu Ser Ile 
625                 630                 635                 640


Ser Thr Arg Lys Val Leu Pro Met Ser Ile Ala Arg His Asn Ile Ala 
                645                 650                 655


Gly Thr Thr His Ser Gly Ala Glu Lys Asp Val Asp Val Ser Glu Asp 
            660                 665                 670


Ser Pro Pro Pro Leu Pro Glu Arg Thr Pro Glu Ser Phe Val Leu Ala 
        675                 680                 685


Ser Glu His Asn Thr Pro Val Arg Ser Glu Trp Ser Glu Leu Gln Ser 
    690                 695                 700


Gln Glu Arg Ser Glu Gln Lys Lys Ser Glu Gly Leu Ile Thr Ser Glu 
705                 710                 715                 720


Asn Glu Lys Cys Asp His Pro Ala Gly Gly Ile His Tyr Glu Met Cys 
                725                 730                 735


Ile Glu Cys Pro Pro Thr Phe Ser Asp Lys Arg Glu Gln Ile Ser Glu 
            740                 745                 750


Asn Pro Thr Glu Ala Thr Asp Ile Gly Phe Gly Asn Arg Cys Gly Lys 
        755                 760                 765


Pro Lys Gly Pro Arg Asp Pro Pro Ser Glu Trp Thr 
    770                 775                 780


<210>  5300
<211>  595
<212>  DNA
<213>  Homo sapiens

<400>  5300
taaaatggtg ttaaacgcat tcaatattta aataattata aatatatttt taattaatag     60

tgctatttat aattaggtaa atatcctaaa agtgatattt taatataatt tcagaagtca    120

caaagtaaat ctgtaagatt tacatgattt aattcaaacc aaaaacatca tgttaattgg    180

aaccaattta atttgttgct gtatagttag cccttgtttg gaaagtctaa ttttgataat    240

ttctttaact tacacattta atattgaaac tactttttta ggcaagccaa ttatacttct    300

cggtgcaaaa ttcttgaaat ctgtatttta ttaaaaagta aaattgtgtt taactgatac    360

gttctttatc tcactcccca ccatcacttt ttagatcatt gtaatggcct gccgagaatt    420

tgagatggga aggaaaaaat gtgagcgcta ttggcctttg tatggagaag accccataac    480

gtttgcacca tttaaaattt cttgtgtaag tatccatttt tgtaaacact tttttcagaa    540

aattggcatg ctatactgat gaataattaa attataatgt ggtatgaacc caggc         595


<210>  5301
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5301

Met Ala Cys Arg Glu Phe Glu Met Gly Arg Lys Lys Cys Glu Arg Tyr 
1               5                   10                  15


Trp Pro Leu Tyr Gly Glu Asp Pro Ile Thr Phe Ala Pro Phe Lys Ile 
            20                  25                  30


Ser Cys Val Ser Ile His Phe Cys Lys His Phe Phe Gln Lys Ile Gly 
        35                  40                  45


Met Leu Tyr 
    50


<210>  5302
<211>  1224
<212>  DNA
<213>  Homo sapiens

<400>  5302
ggaattttta gaatgtcaag aaagctctct gattttgttt agatgacatg ttaatttgtc     60

taaattttta tgtgtttaat ttagatgttg atgttagtga agattcacct cctcccctac    120

ctgaaagaac tcctgaatcg tttgtgttag caagtgaaca taatacacct gtaagatcgg    180

aatggagtga acttcaaagt caggaacgat ctgaacaaaa aaagtctgaa ggcttgataa    240

cctctgaaaa tgagaaatgt gatcatccag cgggaggtat tcactatgaa atgtgcatag    300

aatgtccacc tactttcagt gacaagagag aacaaatatc agaaaatcca acagaagcca    360

cagatattgg ttttggtaat cgatgtggaa aacccaaagg accaagagat ccaccttcag    420

aatggacatg attcagggag ctagaagaca ctttaagtta tactggaaaa ttcaggtgcc    480

actgaaagcc agatttatag tattccatct ttaatatgtg ggactaacag cagtgtagat    540

tgttacctta atattttttg ctgggaccat ctacctgcct tatactacac ttaggaaaaa    600

gtattacata tggtttattt tgaaacttca agtattattg ccttaatgtc tcttaaccct    660

gttacacgct gcttgtagac atgttaatat agtaatacct ttatgatata ttgagtttaa    720

ggactactct ttttctgttt tatcatgtat gcattatttt gtatatgtac agggcaagta    780

ggtatataat ttgataaagt tgcaattgaa atattattaa cagaagatgt aagaaatttc    840

tgcatggtct aaatctttgt gtactttatt tgtaaattat ttgccctgga gttttagaaa    900

atagtttctg aattttaaac ttgctggatt catgcagcca gctttgcagg ttatcagaga    960

tcaaagattg taataataat tttgtaaatt gtaagcaaaa agttattttt atattatata   1020

cagtctaatt gttcatccta attgttcctg ttttcatcta gtcagagatt cagtaagtgc   1080

cttggaacaa tattgaattc tcttagcttg tgtgtgtttc tttaatattt gaactcaagt   1140

gggattagaa gactatcaaa atacatgtat gtttcaggat atttgacctg tcattaaaaa   1200

aaacaaacag ttttacagtg ccta                                          1224


<210>  5303
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  5303

Met Leu Ile Cys Leu Asn Phe Tyr Val Phe Asn Leu Asp Val Asp Val 
1               5                   10                  15


Ser Glu Asp Ser Pro Pro Pro Leu Pro Glu Arg Thr Pro Glu Ser Phe 
            20                  25                  30


Val Leu Ala Ser Glu His Asn Thr Pro Val Arg Ser Glu Trp Ser Glu 
        35                  40                  45


Leu Gln Ser Gln Glu Arg Ser Glu Gln Lys Lys Ser Glu Gly Leu Ile 
    50                  55                  60


Thr Ser Glu Asn Glu Lys Cys Asp His Pro Ala Gly Gly Ile His Tyr 
65                  70                  75                  80


Glu Met Cys Ile Glu Cys Pro Pro Thr Phe Ser Asp Lys Arg Glu Gln 
                85                  90                  95


Ile Ser Glu Asn Pro Thr Glu Ala Thr Asp Ile Gly Phe Gly Asn Arg 
            100                 105                 110


Cys Gly Lys Pro Lys Gly Pro Arg Asp Pro Pro Ser Glu Trp Thr 
        115                 120                 125


<210>  5304
<211>  500
<212>  DNA
<213>  Homo sapiens

<400>  5304
tatttacagt gtctcatgct cagtggaggt gctcacttgt ctaagtacat tttaccaata     60

tattaatttt gactgatttt tgttttgttt catttggttt tctttttatt tatttatttt    120

ttatttattc atttttttga gatggagtct cattctgtcg ccccggctgg agtgcagtgg    180

cacgatctcg gctcactgca agctccacct cttgggttca tgccattctc ctgcctcagc    240

ctctcaaagt gctgggatta caggcatgag ccaccacgcc cggctaattt ttttgtattt    300

ttttagtaga gacagggttt caccatgtta gccaggatgg tctccatctc ctgacctcgt    360

gatcgcccgc ctcagcctcc caaagtgctg ggattacagg cgggagccac cacgcccggc    420

cttgttttgt tttatttcga gttggagttc cactctgtca ctcaggctgg agtgcagtgg    480

cacgatctgg gctcaagctg                                                500


<210>  5305
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  5305

Met Glu Ser His Ser Val Ala Pro Ala Gly Val Gln Trp His Asp Leu 
1               5                   10                  15


Gly Ser Leu Gln Ala Pro Pro Leu Gly Phe Met Pro Phe Ser Cys Leu 
            20                  25                  30


Ser Leu Ser Lys Cys Trp Asp Tyr Arg His Glu Pro Pro Arg Pro Ala 
        35                  40                  45


Asn Phe Phe Val Phe Phe 
    50


<210>  5306
<211>  1247
<212>  DNA
<213>  Homo sapiens

<400>  5306
aacacagctg tatgttcctt catgcagtag cccatgcttt tcagtgctca tccagaaaca     60

tttactccaa ggagaaatag cataacattt taaaatttta agcctaatta aaaaacaatt    120

gtttgctttt cctctgatgc tgaaaatgat aggccttgat ttcttgggat atatacccat    180

aacagaccca gctttctatt atttgtatat aaaatgaatg tattgtaata ggtattaaat    240

gtcttcctcg tagggcttga taacctctga aaatgagaaa tgtgatcatc cagcgggagg    300

tattcactat gaaatgtgca tagaatgtcc acctactttc agtgacaaga gagaacaaat    360

atcagaaaat ccaacagaag ccacagatat tggttttggt aatcgatgtg gaaaacccaa    420

aggaccaaga gatccacctt cagaatggac atgattcagg gagctagaag acactttaag    480

ttatactgga aaattcaggt gccactgaaa gccagattta tagtattcca tctttaatat    540

gtgggactaa cagcagtgta gattgttacc ttaatatttt ttgctgggac catctacctg    600

ccttatacta cacttaggaa aaagtattac atatggttta ttttgaaact tcaagtatta    660

ttgccttaat gtctcttaac cctgttacac gctgcttgta gacatgttaa tatagtaata    720

cctttatgat atattgagtt taaggactac tctttttctg ttttatcatg tatgcattat    780

tttgtatatg tacagggcaa gtaggtatat aatttgataa agttgcaatt gaaatattat    840

taacagaaga tgtaagaaat ttctgcatgg tctaaatctt tgtgtacttt atttgtaaat    900

tatttgccct ggagttttag aaaatagttt ctgaatttta aacttgctgg attcatgcag    960

ccagctttgc aggttatcag agatcaaaga ttgtaataat aattttgtaa attgtaagca   1020

aaaagttatt tttatattat atacagtcta attgttcatc ctaattgttc ctgttttcat   1080

ctagtcagag attcagtaag tgccttggaa caatattgaa ttctcttagc ttgtgtgtgt   1140

ttctttaata tttgaactca agtgggatta gaagactatc aaaatacatg tatgtttcag   1200

gatatttgac ctgtcattaa aaaaaacaaa cagttttaca gtgccta                 1247


<210>  5307
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  5307

Met Cys Ile Glu Cys Pro Pro Thr Phe Ser Asp Lys Arg Glu Gln Ile 
1               5                   10                  15


Ser Glu Asn Pro Thr Glu Ala Thr Asp Ile Gly Phe Gly Asn Arg Cys 
            20                  25                  30


Gly Lys Pro Lys Gly Pro Arg Asp Pro Pro Ser Glu Trp Thr 
        35                  40                  45


<210>  5308
<211>  395
<212>  DNA
<213>  Homo sapiens

<400>  5308
tataaaatga atgtattgta ataggtatta aatgtcttcc tcgtagggct tgataacctc     60

tgaaaatgag aaatgtgatc atccagcggg aggtattcac tatgaaatgt gcatagaatg    120

tccacctact ttcagtgaca agagagaaca aatatcagaa aatccaacag aagccacaga    180

tattggtaat ttgtttaata aataattttt agtaagtagt taacactggc aggaatgaga    240

aaagctcatt tgccattgtg aaatgacact tgccaagaat aaaacatgat tttccaaagt    300

tgcttggact agtcatgaaa taaatgaaat acttaattct atttcacatt gagattaaaa    360

actaaaatag aaaactgcag tataaaaaat ctttt                               395


<210>  5309
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  5309

Met Cys Ile Glu Cys Pro Pro Thr Phe Ser Asp Lys Arg Glu Gln Ile 
1               5                   10                  15


Ser Glu Asn Pro Thr Glu Ala Thr Asp Ile Gly Asn Leu Phe Asn Lys 
            20                  25                  30


<210>  5310
<211>  2832
<212>  DNA
<213>  Homo sapiens

<400>  5310
cggcacccac ctcggggcag cggcttcacc tccccgttct cctcccggga ggccccgccg     60

gcctctcggg ccccaccgag accgtgcctc ctcctctcct tctcccgctt ctccttaggt    120

ctgcgcgact tggcgttagc cgaggcagcg gcggcggcgg cgggcaggag gagatggtga    180

ggctgagcgt gcagcagcgt aggagggacc agcagtttgc gcggcaccgg ctgagacaag    240

gaagcggagg ctgaggaggg aacggccgtg ccagcggaga aagagaaact gctccgagaa    300

gaggacgggg agggagcagc agacagaggg gcaaagctcc aagacgcggg gctgccatag    360

ctctgaggcg aaggtgctgc cggcggctgc agctgcctgc tgttcccgcc gctgccccct    420

tctccgttca ctctccgcgg tgccttcttc tcctcagtcc ggaccttctt ggcggacaga    480

gaacccggag ggtcccggga ggagagttgc agcttgccaa acggttcttt ctccgagacg    540

gtggcggtgg gggccgcggc agcgacacag tgcacggggc tcggcggttc cgccattttg    600

cgctcctgtt gtatttactc tcctccgcta gccggcgcgg ggcagggggc gggccctccg    660

cgaggggtag ggaaggggcg gagcggccag gccaccagcc ggcattgctc cattgggcaa    720

gccacgctga gggatccacc taagagccaa tcaaaggcac aaacatcaga cgaaggggcg    780

ggatcgccac agggaccctc ttcggaggtc agagctcggc ggggtgcggc tagtggcgga    840

gcgcgctgcg aggggagggc tttccactgt cgctggcgtg aactcgcgtg cccggtgggt    900

atcagggaag aacccccgcc ccggaccccc agatctgcca tggccgaggt agcgatcgtc    960

tctgcggcca cgaagactgt tttaacttgt accactttcc cttccatttt tcctggggtg   1020

cctctcaccc tgcatctgcg cgttcagcaa gctggatttc gggaatgctc agttcagaag   1080

agaaaaaatt gccgggaatc aagtccttct ttttgttagt cggtagtcga ttgatgggaa   1140

gtgttcaaaa tcattcgatg tggtgacaag gtatcaccag tctgtgggta caaaaggaga   1200

gtaacatgaa cgattcaaat tccactggct cttgttccca tggattcaca gaagttcagc   1260

cccatttcaa aacttcacat ttgcttctgg gaagcccatt ctggaaagtt tctctgtggc   1320

cctctccaga aggcagcgcg acttccaccc agcaacacaa gtctctgcag cacctgcccc   1380

agcagcgcca gctgagcccc ggaagctggg aaggcttaag ctgactcttc tgctgcacat   1440

agcaaaaaat ggtcatttct gtagttgcag ctccagatct acaataatca atctatatcc   1500

atattttatg gggttttttt gagacaaagt cttgctctgt tactcaggct ggagtgcagt   1560

ggcattatca tcattcactt gtagccttga cctccctggc tcaggtgatc ctgtcacctc   1620

agccttccaa gtagctgaga ccacaggcat gcaccactaa gcctggctaa tttttcaatt   1680

tttatttttc gtagagacag ggtctccctg ggttgcccaa actggtcttg aattcctggg   1740

ctcaagcaat cctcctgtcc cggcaccccg aagtgttggg actacaggca tgagccactg   1800

tgcacagccc tttttgtttt tgtttttgtt tttttttaaa ggtaatttcc cagtggaatc   1860

ctcgagattt cttcacgttt ttggaaaaat gagttacatt ttagattgtt ttcctttttg   1920

gaatttaatg gtatacatta tattacatag ctatgttgag ctctatttct attacactaa   1980

aaagtaggct aattgtctta actttcatca gtaatgacat taaatgtgtg aagattatac   2040

ttggaataaa gcacttggat tcattcattt cttcagtaaa tatttattga gcactagtat   2100

gttccaacga gtgtctgtct acattctggg gacaagtgat aactaaatcc ctgtcctcgt   2160

ggagagttaa caatcaacaa actaacaaac atttaattta tgtcatcaac tcatttccac   2220

aaatataaca acatcttgac ttcaagtttc ctgagtttct ggtctaaaga attgctacct   2280

tcaagagctc aaatcatttg ttggggagag aggcctgtga tatattttct cctttacaat   2340

gaaagtagct gtaaaaagag gaagagaaat tctgagggta aagataaaaa atgttgaaat   2400

cttctttctg gatttcagat tgagtctctt gccctaattg atgcaattta cactccatgc   2460

atctccttcc ctggaccttc tccagttctt ggggactaca gatgaactta cttttaatgc   2520

attttatggc atttggaggc cctccagtgg acaaatacta tacctgaaaa aaatcctttt   2580

gctgtgctaa agtgttcagg tgtgaagtgt actcatgttt gcaaatcact ttgaaatata   2640

taaacaaaaa tgaattaatg gatgaataga gtgatgcata gatcattaga catgtgataa   2700

aaataactgt taattgtaga atctagatga tgagtatatt atatgatatg gcccactgta   2760

taattctttc aacttttctg tttgaatgtt tgataataaa atattgaata aaaatctttt   2820

tgctaaagat tt                                                       2832


<210>  5311
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  5311

Met Asn Asp Ser Asn Ser Thr Gly Ser Cys Ser His Gly Phe Thr Glu 
1               5                   10                  15


Val Gln Pro His Phe Lys Thr Ser His Leu Leu Leu Gly Ser Pro Phe 
            20                  25                  30


Trp Lys Val Ser Leu Trp Pro Ser Pro Glu Gly Ser Ala Thr Ser Thr 
        35                  40                  45


Gln Gln His Lys Ser Leu Gln His Leu Pro Gln Gln Arg Gln Leu Ser 
    50                  55                  60


Pro Gly Ser Trp Glu Gly Leu Ser 
65                  70


<210>  5312
<211>  1435
<212>  DNA
<213>  Homo sapiens

<400>  5312
cggcacccac ctcggggcag cggcttcacc tccccgttct cctcccggga ggccccgccg     60

gcctctcggg ccccaccgag accgtgcctc ctcctctcct tctcccgctt ctccttaggt    120

ctgcgcgact tggcgttagc cgaggcagcg gcggcggcgg cgggcaggag gagatggtga    180

ggctgagcgt gcagcagcgt aggagggacc agcagtttgc gcggcaccgg ctgagacaag    240

gaagcggagg ctgaggaggg aacggccgtg ccagcggaga aagagaaact gctccgagaa    300

gaggacgggg agggagcagc agacagaggg gcaaagctcc aagacgcggg gctgccatag    360

ctctgaggcg aaggtgctgc cggcggctgc agctgcctgc tgttcccgcc gctgccccct    420

tctccgttca ctctccgcgg tgccttcttc tcctcagtcc ggaccttctt ggcggacaga    480

gaacccggag ggtcccggga ggagagttgc agcttgccaa acggttcttt ctccgagacg    540

gtggcggtgg gggccgcggc agcgacacag tgcacggggc tcggcggttc cgccattttg    600

cgctcctgtt gtatttactc tcctccgcta gccggcgcgg ggcagggggc gggccctccg    660

cgaggggtag ggaaggggcg gagcggccag gccaccagcc ggcattgctc cattgggcaa    720

gccacgctga gggatccacc taagagccaa tcaaaggcac aaacatcaga cgaaggggcg    780

ggatcgccac agggaccctc ttcggaggtc agagctcggc ggggtgcggc tagtggcgga    840

gcgcgctgcg aggggagggc tttccactgt cgctggcgtg aactcgcgtg cccggtgggt    900

atcagggaag aacccccgcc ccggaccccc agatctgcca tggccgaggt agcgatcgtc    960

tctgcggcca cgaagactgt tttaacttgt accactttcc cttccatttt tcctggggtg   1020

cctctcaccc tgcatctgcg cgttcagcaa gctggatttc gggaatgctc agttcagaag   1080

agaaaaaatt gccgggaatc aagtccttct ttttgttagt cggtagtcga ttgatgggaa   1140

gtgttcaaaa tcattcgatg tggtgacaag gcttcaccag gtactgcctt ctaacgagct   1200

ggccatttcc acatgtcaga taggaccaac ttgcctttta actacccgtg tgatacttaa   1260

acactgttgc cggtatcaca gcttttcttc aaaacaggta atattaggga cacagtctgt   1320

gggtacaaaa ggagagtaac atgaacgatt caaattccac tggctcttgt tcccatggat   1380

tcacagaagt tcagccccat ttcaaaactt cacatttgct tctgggaagc ccatt        1435


<210>  5313
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5313

Met Ala Glu Val Ala Ile Val Ser Ala Ala Thr Lys Thr Val Leu Thr 
1               5                   10                  15


Cys Thr Thr Phe Pro Ser Ile Phe Pro Gly Val Pro Leu Thr Leu His 
            20                  25                  30


Leu Arg Val Gln Gln Ala Gly Phe Arg Glu Cys Ser Val Gln Lys Arg 
        35                  40                  45


Lys Asn Cys Arg Glu Ser Ser Pro Ser Phe Cys 
    50                  55


<210>  5314
<211>  2291
<212>  DNA
<213>  Homo sapiens

<400>  5314
ggagagtagg gtgcagggag ggtaccttac gaaacagcgc acttcgggcc ctgcacgcta     60

cctcatttcc ctaataggga tgaaaagctc aggcctctgg tagcttccag ctgacgccag    120

tgctctctcc acaccccttt tttgacagga ttatccgggg ttgaacgctg tgtcacaaat    180

acgaattccc gcgaccacgt ctaagtggtc taacaatcaa tcaagcatct tttacaaaac    240

caaacccttc ccccatcccg ttccctccat ctctctccct agccaaacaa acctaggaga    300

gtcctcaaga tggattttca caaatcctgc agcgcactaa ctgggaggaa gaaacgatac    360

agaaaataag agtgtcggcc atccccctct ctgcaaccga aattacaggc tccatttcct    420

gtccccttgg gaactgcaaa atcctctgct gaaaaccgga cgcctcccag cccctccagg    480

ccggcgcacg cggccgccgc gctccccctt cccgggcccc gtgggcgcca gggggcggcg    540

gggacccacg gcgccctccc ctccccctcc ccgcacggca cccacctcgg ggcagcggct    600

tcacctcccc gttctcctcc cgggaggccc cgccggcctc tcgggcccca ccgagaccgt    660

gcctcctcct ctccttctcc cgcttctcct taggtctgcg cgacttggcg ttagccgagg    720

cagcggcggc ggcggcgggc aggaggagat ggtgaggctg agcgtgcagc agcgtaggag    780

ggaccagcag tttgcgcggc accggctgag acaaggaagc ggaggctgag gagggaacgg    840

ccgtgccagc ggagaaagag aaactgctcc gagaagagga cggggaggga gcagcagaca    900

gaggggcaaa gctccaagac gcggggctgc catagctctg aggcgaaggt gctgccggcg    960

gctgcagctg cctgctgttc ccgccgctgc ccccttctcc gttcactctc cgcggtgcct   1020

tcttctcctc agtccggacc ttcttggcgg acagagaacc cggagggtcc cgggaggaga   1080

gttgcagctt gccaaacggt tctttctccg agacggtggc ggtgggggcc gcggcagcga   1140

cacagtgcac ggggctcggc ggttccgcca ttttgcgctc ctgttgtatt tactctcctc   1200

cgctagccgg cgcggggcag ggggcgggcc ctccgcgagg ggtagggaag gggcggagcg   1260

gccaggccac cagccggcat tgctccattg ggcaagccac gctgagggat ccacctaaga   1320

gccaatcaaa ggcacaaaca tcagacgaag gggcgggatc gccacaggga ccctcttcgg   1380

aggtcagagc tcggcggggt gcggctagtg gcggagcgcg ctgcgagggg agggctttcc   1440

actgtcgctg gcgtgaactc gcgtgcccgg tgggtatcag ggaagaaccc ccgccccgga   1500

cccccagatc tgccatggcc gaggtagcga tcgtctctgc ggccacgaag actgttttaa   1560

cttgtaccac tttcccttcc atttttcctg gggtgcctct caccctgcat ctgcgcgttc   1620

agcaagctgg atttcgggaa tgctcagttc agaagagaaa aaattgccgg gaatcaagtc   1680

cttctttttg ttagtcggta gtcgattgat gggaagtgtt caaaatcatt cgatgtggtg   1740

acaaggcttc accaggtact gccttctaac gagctggcca tttccacatg tcagatagga   1800

ccaacttgcc ttttaactac ccgtgtgata cttaaacact gttgccggta tcacagcttt   1860

tcttcaaaac aggaagcaac gagaatgagg gcattccagt agcaggagac agcatgcata   1920

gagatgctga tgaagaaaga gcctagcgca cgtgggaaac tgcaaaagtt cagactggtt   1980

ggaatgctgg aaatgttgtg aatgacagga gatgaggctg gcgagaaaac agaggtcaga   2040

ttgtggaagg ctgtcaagcc aaagactttg attttattct tgagattgat gagatgtgtg   2100

taatccagga gtgtgcaaaa caatctgtaa gggttcagaa aacatactgc ttctatatat   2160

agttaccttt gtcttaactt gaaaatttca aattgtgtag gagttacaat gtgtgtaatt   2220

gttattatag tactggatcc aaataattta taaataaata aatatagaca taatatggtg   2280

tattacaggt t                                                        2291


<210>  5315
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5315

Met Ala Glu Val Ala Ile Val Ser Ala Ala Thr Lys Thr Val Leu Thr 
1               5                   10                  15


Cys Thr Thr Phe Pro Ser Ile Phe Pro Gly Val Pro Leu Thr Leu His 
            20                  25                  30


Leu Arg Val Gln Gln Ala Gly Phe Arg Glu Cys Ser Val Gln Lys Arg 
        35                  40                  45


Lys Asn Cys Arg Glu Ser Ser Pro Ser Phe Cys 
    50                  55


<210>  5316
<211>  2570
<212>  DNA
<213>  Homo sapiens

<400>  5316
cggcacccac ctcggggcag cggcttcacc tccccgttct cctcccggga ggccccgccg     60

gcctctcggg ccccaccgag accgtgcctc ctcctctcct tctcccgctt ctccttaggt    120

ctgcgcgact tggcgttagc cgaggcagcg gcggcggcgg cgggcaggag gagatggtga    180

ggctgagcgt gcagcagcgt aggagggacc agcagtttgc gcggcaccgg ctgagacaag    240

gaagcggagg ctgaggaggg aacggccgtg ccagcggaga aagagaaact gctccgagaa    300

gaggacgggg agggagcagc agacagaggg gcaaagctcc aagacgcggg gctgccatag    360

ctctgaggcg aaggtgctgc cggcggctgc agctgcctgc tgttcccgcc gctgccccct    420

tctccgttca ctctccgcgg tgccttcttc tcctcagtcc ggaccttctt ggcggacaga    480

gaacccggag ggtcccggga ggagagttgc agcttgccaa acggttcttt ctccgagacg    540

gtggcggtgg gggccgcggc agcgacacag tgcacggggc tcggcggttc cgccattttg    600

cgctcctgtt gtatttactc tcctccgcta gccggcgcgg ggcagggggc gggccctccg    660

cgaggggtag ggaaggggcg gagcggccag gccaccagcc ggcattgctc cattgggcaa    720

gccacgctga gggatccacc taagagccaa tcaaaggcac aaacatcaga cgaaggggcg    780

ggatcgccac agggaccctc ttcggaggtc agagctcggc ggggtgcggc tagtggcgga    840

gcgcgctgcg aggggagggc tttccactgt cgctggcgtg aactcgcgtg cccggtgggt    900

atcagggaag aacccccgcc ccggaccccc agatctgcca tggccgaggt agcgatcgtc    960

tctgcggcca cgaagactgt tttaacttgt accactttcc cttccatttt tcctggggtg   1020

cctctcaccc tgcatctgcg cgttcagcaa gctggatttc gggaatgctc agttcagaag   1080

agaaaaaatt gccgggaatc aagtccttct ttttgttagt cggtagtcga ttgatgggaa   1140

gtgttcaaaa tcattcgatg tggtgacaag gcttcaccag gtactgcctt ctaacgagct   1200

ggccatttcc acatgtcaga taggaccaac ttgcctttta actacccgtg tgatacttaa   1260

acactgttgc cggtatcaca gcttttcttc aaaacaggta atattaggga cacttgaaat   1320

ttgggaatta gatttacctt tgctgttact aaataattgt tagaatttta aatgtcatat   1380

tcattttact caactaatct ctttagcttt cctatttata ttcctactta tgattacgtg   1440

taattctcat tggaaggatt aaaatatttt gaaagtaaga cagtaaaatt gtgaaatact   1500

ttggtattgg ttacaaaaca gtacttaggt accttcttcc tgatttttct gtatttttaa   1560

aaaataaggc caggcacagt ggcaaatgct tatattccca actgcccagt aagctgaagc   1620

aagagaattg cttgagccca acctgggcaa catagtgaaa ccccagtcac caattaaaaa   1680

caaacaaaca aaaagagtat attttttgaa gatattttat cacatataca gaagcaaaca   1740

aagaggggaa ggaattgttt aaaataatgt taagctaaat aaagtcaaag aaaatttaag   1800

taatagttaa tagttattgt tatagaagac atcaatttac taccccgttc tcaaaaagga   1860

aaatctgcaa gtagactgta gtgctagagt aagcttttcc ttaatttcag aaagcctgta   1920

ttaagcattt actttatgcc aaactccatt ttagggactg gaaatataaa ataaataaaa   1980

cacagtccct gctctcagtg aacttgttgt ctagggaatg ttaagtagaa ccacctgaaa   2040

ttgcattgtt tttgtaagcc agctatcggt tccacctgac attatatgtg gaaacagaaa   2100

tttgcaataa taaagatatg accacggtgc tacggggcac tgacaaaatg cttcatgctg   2160

cccagggcag tcagtgaagg ctccccaggg gagatgacgt ttgagccgag tttcagaaga   2220

tgattggagt ttaccacgtg ttcacaggaa gcaacgagaa tgagggcatt ccagtagcag   2280

gagacagcat gcatagagat gctgatgaag aaagagccta gcgcacgtgg gaaactgcaa   2340

aagttcagac tggttggaat gctggaaatg ttgtgaatga caggagatga ggctggcgag   2400

aaaacagagg tcagattgtg gaaggctgtc aagccaaaga ctttgatttt attcttgaga   2460

ttgatgagat gtgtgtaatc caggagtgtg caaaacaatc tgtaagggtt cagaaaacat   2520

actgcttcta tatatagtta cctttgtctt aacttgaaaa tttcaaattg              2570


<210>  5317
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5317

Met Ala Glu Val Ala Ile Val Ser Ala Ala Thr Lys Thr Val Leu Thr 
1               5                   10                  15


Cys Thr Thr Phe Pro Ser Ile Phe Pro Gly Val Pro Leu Thr Leu His 
            20                  25                  30


Leu Arg Val Gln Gln Ala Gly Phe Arg Glu Cys Ser Val Gln Lys Arg 
        35                  40                  45


Lys Asn Cys Arg Glu Ser Ser Pro Ser Phe Cys 
    50                  55


<210>  5318
<211>  1402
<212>  DNA
<213>  Homo sapiens

<400>  5318
ctcggggcag cggcttcacc tccccgttct cctcccggga ggccccgccg gcctctcggg     60

ccccaccgag accgtgcctc ctcctctcct tctcccgctt ctccttaggt ctgcgcgact    120

tggcgttagc cgaggcagcg gcggcggcgg cgggcaggag gagatggtga ggctgagcgt    180

gcagcagcgt aggagggacc agcagtttgc gcggcaccgg ctgagacaag gaagcggagg    240

ctgaggaggg aacggccgtg ccagcggaga aagagaaact gctccgagaa gaggacgggg    300

agggagcagc agacagaggg gcaaagctcc aagacgcggg gctgccatag ctctgaggcg    360

aaggtgctgc cggcggctgc agctgcctgc tgttcccgcc gctgccccct tctccgttca    420

ctctccgcgg tgccttcttc tcctcagtcc ggaccttctt ggcggacaga gaacccggag    480

ggtcccggga ggagagttgc agcttgccaa acggttcttt ctccgagacg gtggcggtgg    540

gggccgcggc agcgacacag tgcacggggc tcggcggttc cgccattttg cgctcctgtt    600

gtatttactc tcctccgcta gccggcgcgg ggcagggggc gggccctccg cgaggggtag    660

ggaaggggcg gagcggccag gccaccagcc ggcattgctc cattgggcaa gccacgctga    720

gggatccacc taagagccaa tcaaaggcac aaacatcaga cgaaggggcg ggatcgccac    780

agggaccctc ttcggaggtc agagctcggc ggggtgcggc tagtggcgga gcgcgctgcg    840

aggggagggc tttccactgt cgctggcgtg aactcgcgtg cccggcttca ccaggtactg    900

ccttctaacg agctggccat ttccacatgt cagataggac caacttgcct tttaactacc    960

cgtgtgatac ttaaacactg ttgccggtat cacagctttt cttcaaaaca gggcagtcag   1020

tgaaggctcc ccaggggaga tgacgtttga gccgagtttc agaagatgat tggagtttac   1080

cacgtgttca caggaagcaa cgagaatgag ggcattccag tagcaggaga cagcatgcat   1140

agagatgctg atgaagaaag agcctagcgc acgtgggaaa ctgcaaaagt tcagactggt   1200

tggaatgctg gaaatgttgt gaatgacagg agatgaggct ggcgagaaaa cagaggtcag   1260

attgtggaag gctgtcaagc caaagacttt gattttattc ttgagattga tgagatgtgt   1320

gtaatccagg agtgtgcaaa acaatctgta agggttcaga aaacatactg cttctatata   1380

tagttacctt tgtcttaact tg                                            1402


<210>  5319
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  5319

Met Ile Gly Val Tyr His Val Phe Thr Gly Ser Asn Glu Asn Glu Gly 
1               5                   10                  15


Ile Pro Val Ala Gly Asp Ser Met His Arg Asp Ala Asp Glu Glu Arg 
            20                  25                  30


Ala 



<210>  5320
<211>  3105
<212>  DNA
<213>  Homo sapiens

<400>  5320
ccgcgccggc tagcggagga gagtaaatac aacaggagcg caaaatggcg gaaccgccga     60

gccccgtgca ctgtgtcgct gccgcggccc ccaccgccac cgtctcggag aaagaaccgt    120

ttggcaagct gcaactctcc tcccgggacc ctccgggttc tctgtccgcc aagaaggtcc    180

ggactgagga gaagaaggca ccgcggagag tgaacggaga agggggcagc ggcgggaaca    240

gcaggcagct gcagccgccg gcagcacctt cgcctcagag ctatggcagc cccgcgtctt    300

ggagctttgc ccctctgtct gctgctccct ccccgtcctc ttctcggagc agtttctctt    360

tctccgctgg cacggccgtt ccctcctcag cctccgcttc cttgtctcag ccggtgccgc    420

gcaaactgct ggtccctcct acgctgctgc acgctcagcc tcaccatctc ctcctgcccg    480

ccgccgccgc cgctgcctcg gctaacgcca agtcgcgcag acctaaggag aagcgggaga    540

aggagaggag gaggcacggt ctcggtgggg cccgagaggc cggcggggcc tcccgggagg    600

agaacgggga ggtgaagccg ctgccccgag ataaaatcaa agacaaaatt aaagagagag    660

acaaagaaaa agaaagagaa aaaaagaaac ataaagtaat gaatgagatc aagaaagaga    720

atggagaagt aaagattttg ctgaaaagtg ggaaggagaa accaaaaaca aatatagaag    780

acttacaaat taaaaaggta aagaagaaaa agaaaaagaa acacaaagag aatgaaaaac    840

ggaagcgtcc gaaaatgtat agcaaatcta ttcagaccat ctgctcagga ttgctaactg    900

atgttgaaga tcaagcagcc aaaggcatcc taaatgataa cataaaagat tacgttggga    960

agaatttgga taccaagaac tatgattcca aaattccaga gaacagtgag tttccatttg   1020

tctcattaaa ggagccacga gttcagaata acctcaaaag gttggacact ttggaattta   1080

aacaactcat tcatatagag caccagccta atggaggtgc atcggttatc catgcctaca   1140

gtaacgaact ctcccacctg tctcctatgg agatggagag gtttgcagaa gagtttgtgg   1200

gtctagtgtt cagtgaaaat gaaaactctg cagctttcta cgtgatgggt attgttcatg   1260

gggcagctac ttatttacct gactttttag actatttttc atttaatttt cccaattcac   1320

cagtgaaaat ggagatattg ggaaagaaag atatagagac aacgactatg tccaattttc   1380

atgctcaggt aaaaagaacg tattctcatg gtacttacag agctggccca atgagacaaa   1440

taagcttggt gggagcagtt gatgaagaag taggagatta tttccctgag ttccttgaca   1500

tgttggaaga gtcaccattt ttaaaatgta cactgccatg ggggacgcta tctagtctaa   1560

aattacagag tcgaaaagat agtgatgatg gtcccatcat gtgggttcgt ccaggagaac   1620

aaatgatccc tgtggctgat atgccaaagt cacctttcaa aaggaaaaga actaccaatg   1680

aaataaaaaa tcttcagtac ctacctcgaa caagtgagcc ccgtgagatg ctctttgaag   1740

acaggacaag agctcatgca gatcatatag gacaaggttt tgaacgacag actacagctg   1800

ctgttggagt gctgaaggct gtgcactgtg gagagtggcc tgatcaaccc cgtataacca   1860

aagatgtaat ttgttttcat gctgaagatt tcttagaagt agttcaacga atgcagttag   1920

atttacatga acctccactg tcccagtgtg tccaatgggt tgatgatgca aaactgaatc   1980

aactgaggag ggaaggcatt cgctatgcca ggattcagct atatgataat gacatttatt   2040

ttattccaag gaatgttgtt catcagttca agacagtttc agctgtatgc agtttagcat   2100

ggcatattcg gctcaaatta tatcactcag aggaggacac ttctcagaat acagctactc   2160

atgaaacagg cacatcatca gattccacat catctgttct tggacctcac actgacaaca   2220

tgatttgtgc tgtaagcaaa gcctccttgg attctgtttt ttcagataaa cttcattcta   2280

aatatgaatt acagcagatt aaacatgaac ctattgcatc tgtaagaatc aaggaagaac   2340

ctgtgaatgt taatattcct gaaaagacta cagcactgaa taatatggat ggcaagaatg   2400

ttaaagcaaa attggatcat gttcaatttg cagaatttaa gattgacatg gattctaaat   2460

ttgaaaatag caacaaagat ttaaaggaag aattgtgccc tggaaatcta agtctagttg   2520

atacaaggca acacagttca gcacattcaa atcaagataa aaaagacgat gacattttgt   2580

gctaaatttg catataccat ctaaaatcct tttttaaaaa aatttaatgt aataaagatt   2640

catgaattct gaaagcaagc caaggacttg ctcctatgtc tgttacaaaa catagtttat   2700

gtagctttgt aacattcctc agtgcctgtc cataactgtg aagtattaag cacttagggc   2760

cagatgcact gtaaacattg caggtttaaa cataaaggag tctttaaaaa aaaatcattt   2820

acgttggaat tttaggtttt agaatagagc tgacattaac atatatatat atatataaat   2880

atatatatat attttgtaat atgagccaga attctttttc aacaatttaa agcttttcca   2940

tagagcttat ttatatcctt ttttttcatt ttaaatgtgt cagcactgta gtgtaaatag   3000

cttttaaata tctttttagt gtgatttata ctgaaatgtg agccacttaa taaaggttca   3060

tatgttcata ttaataaata tgttttctgt tgagtctgta aagac                   3105


<210>  5321
<211>  846
<212>  PRT
<213>  Homo sapiens

<400>  5321

Met Ala Glu Pro Pro Ser Pro Val His Cys Val Ala Ala Ala Ala Pro 
1               5                   10                  15


Thr Ala Thr Val Ser Glu Lys Glu Pro Phe Gly Lys Leu Gln Leu Ser 
            20                  25                  30


Ser Arg Asp Pro Pro Gly Ser Leu Ser Ala Lys Lys Val Arg Thr Glu 
        35                  40                  45


Glu Lys Lys Ala Pro Arg Arg Val Asn Gly Glu Gly Gly Ser Gly Gly 
    50                  55                  60


Asn Ser Arg Gln Leu Gln Pro Pro Ala Ala Pro Ser Pro Gln Ser Tyr 
65                  70                  75                  80


Gly Ser Pro Ala Ser Trp Ser Phe Ala Pro Leu Ser Ala Ala Pro Ser 
                85                  90                  95


Pro Ser Ser Ser Arg Ser Ser Phe Ser Phe Ser Ala Gly Thr Ala Val 
            100                 105                 110


Pro Ser Ser Ala Ser Ala Ser Leu Ser Gln Pro Val Pro Arg Lys Leu 
        115                 120                 125


Leu Val Pro Pro Thr Leu Leu His Ala Gln Pro His His Leu Leu Leu 
    130                 135                 140


Pro Ala Ala Ala Ala Ala Ala Ser Ala Asn Ala Lys Ser Arg Arg Pro 
145                 150                 155                 160


Lys Glu Lys Arg Glu Lys Glu Arg Arg Arg His Gly Leu Gly Gly Ala 
                165                 170                 175


Arg Glu Ala Gly Gly Ala Ser Arg Glu Glu Asn Gly Glu Val Lys Pro 
            180                 185                 190


Leu Pro Arg Asp Lys Ile Lys Asp Lys Ile Lys Glu Arg Asp Lys Glu 
        195                 200                 205


Lys Glu Arg Glu Lys Lys Lys His Lys Val Met Asn Glu Ile Lys Lys 
    210                 215                 220


Glu Asn Gly Glu Val Lys Ile Leu Leu Lys Ser Gly Lys Glu Lys Pro 
225                 230                 235                 240


Lys Thr Asn Ile Glu Asp Leu Gln Ile Lys Lys Val Lys Lys Lys Lys 
                245                 250                 255


Lys Lys Lys His Lys Glu Asn Glu Lys Arg Lys Arg Pro Lys Met Tyr 
            260                 265                 270


Ser Lys Ser Ile Gln Thr Ile Cys Ser Gly Leu Leu Thr Asp Val Glu 
        275                 280                 285


Asp Gln Ala Ala Lys Gly Ile Leu Asn Asp Asn Ile Lys Asp Tyr Val 
    290                 295                 300


Gly Lys Asn Leu Asp Thr Lys Asn Tyr Asp Ser Lys Ile Pro Glu Asn 
305                 310                 315                 320


Ser Glu Phe Pro Phe Val Ser Leu Lys Glu Pro Arg Val Gln Asn Asn 
                325                 330                 335


Leu Lys Arg Leu Asp Thr Leu Glu Phe Lys Gln Leu Ile His Ile Glu 
            340                 345                 350


His Gln Pro Asn Gly Gly Ala Ser Val Ile His Ala Tyr Ser Asn Glu 
        355                 360                 365


Leu Ser His Leu Ser Pro Met Glu Met Glu Arg Phe Ala Glu Glu Phe 
    370                 375                 380


Val Gly Leu Val Phe Ser Glu Asn Glu Asn Ser Ala Ala Phe Tyr Val 
385                 390                 395                 400


Met Gly Ile Val His Gly Ala Ala Thr Tyr Leu Pro Asp Phe Leu Asp 
                405                 410                 415


Tyr Phe Ser Phe Asn Phe Pro Asn Ser Pro Val Lys Met Glu Ile Leu 
            420                 425                 430


Gly Lys Lys Asp Ile Glu Thr Thr Thr Met Ser Asn Phe His Ala Gln 
        435                 440                 445


Val Lys Arg Thr Tyr Ser His Gly Thr Tyr Arg Ala Gly Pro Met Arg 
    450                 455                 460


Gln Ile Ser Leu Val Gly Ala Val Asp Glu Glu Val Gly Asp Tyr Phe 
465                 470                 475                 480


Pro Glu Phe Leu Asp Met Leu Glu Glu Ser Pro Phe Leu Lys Cys Thr 
                485                 490                 495


Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys Leu Gln Ser Arg Lys Asp 
            500                 505                 510


Ser Asp Asp Gly Pro Ile Met Trp Val Arg Pro Gly Glu Gln Met Ile 
        515                 520                 525


Pro Val Ala Asp Met Pro Lys Ser Pro Phe Lys Arg Lys Arg Thr Thr 
    530                 535                 540


Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro Arg Thr Ser Glu Pro Arg 
545                 550                 555                 560


Glu Met Leu Phe Glu Asp Arg Thr Arg Ala His Ala Asp His Ile Gly 
                565                 570                 575


Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala Val Gly Val Leu Lys Ala 
            580                 585                 590


Val His Cys Gly Glu Trp Pro Asp Gln Pro Arg Ile Thr Lys Asp Val 
        595                 600                 605


Ile Cys Phe His Ala Glu Asp Phe Leu Glu Val Val Gln Arg Met Gln 
    610                 615                 620


Leu Asp Leu His Glu Pro Pro Leu Ser Gln Cys Val Gln Trp Val Asp 
625                 630                 635                 640


Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu Gly Ile Arg Tyr Ala Arg 
                645                 650                 655


Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe Ile Pro Arg Asn Val Val 
            660                 665                 670


His Gln Phe Lys Thr Val Ser Ala Val Cys Ser Leu Ala Trp His Ile 
        675                 680                 685


Arg Leu Lys Leu Tyr His Ser Glu Glu Asp Thr Ser Gln Asn Thr Ala 
    690                 695                 700


Thr His Glu Thr Gly Thr Ser Ser Asp Ser Thr Ser Ser Val Leu Gly 
705                 710                 715                 720


Pro His Thr Asp Asn Met Ile Cys Ala Val Ser Lys Ala Ser Leu Asp 
                725                 730                 735


Ser Val Phe Ser Asp Lys Leu His Ser Lys Tyr Glu Leu Gln Gln Ile 
            740                 745                 750


Lys His Glu Pro Ile Ala Ser Val Arg Ile Lys Glu Glu Pro Val Asn 
        755                 760                 765


Val Asn Ile Pro Glu Lys Thr Thr Ala Leu Asn Asn Met Asp Gly Lys 
    770                 775                 780


Asn Val Lys Ala Lys Leu Asp His Val Gln Phe Ala Glu Phe Lys Ile 
785                 790                 795                 800


Asp Met Asp Ser Lys Phe Glu Asn Ser Asn Lys Asp Leu Lys Glu Glu 
                805                 810                 815


Leu Cys Pro Gly Asn Leu Ser Leu Val Asp Thr Arg Gln His Ser Ser 
            820                 825                 830


Ala His Ser Asn Gln Asp Lys Lys Asp Asp Asp Ile Leu Cys 
        835                 840                 845


<210>  5322
<211>  514
<212>  DNA
<213>  Homo sapiens

<400>  5322
aggagcgcaa aatggcggaa ccgccgagcc ccgtgcactg tgtcgctgcc gcggccccca     60

ccgccaccgt ctcggagaaa gaaccgtttg gcaagctgca actctcctcc cgggaccctc    120

cgggttctct gtccgccaag aaggtccgga ctgaggagaa gaaggcaccg cggagagtga    180

acggagaagg gggcagcggc gggaacagca ggcagctgca gccgccggca gcaccttcgc    240

ctcagagcta tggcagcggc cgttccctcc tcagcctccg cttccttgtc tcagccggtg    300

ccgcgcaaac tgctggtccc tcctacgctg ctgcacgctc agcctcacca tctcctcctg    360

cccgccgccg ccgccgctgc ctcggctaac gccaagtcgc gcagacctaa ggagaagcgg    420

gagaaggaga ggaggaggca cggtctcggt ggggcccgag aggccggcgg ggcctcccgg    480

gaggagaacg gggaggtgaa gccgctgccc cgag                                514


<210>  5323
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5323

Met Ala Glu Pro Pro Ser Pro Val His Cys Val Ala Ala Ala Ala Pro 
1               5                   10                  15


Thr Ala Thr Val Ser Glu Lys Glu Pro Phe Gly Lys Leu Gln Leu Ser 
            20                  25                  30


Ser Arg Asp Pro Pro Gly Ser Leu Ser Ala Lys Lys Val Arg Thr Glu 
        35                  40                  45


Glu Lys Lys Ala Pro Arg Arg Val Asn Gly Glu Gly Gly Ser Gly Gly 
    50                  55                  60


Asn Ser Arg Gln Leu Gln Pro Pro Ala Ala Pro Ser Pro Gln Ser Tyr 
65                  70                  75                  80


Gly Ser Gly Arg Ser Leu Leu Ser Leu Arg Phe Leu Val Ser Ala Gly 
                85                  90                  95


Ala Ala Gln Thr Ala Gly Pro Ser Tyr Ala Ala Ala Arg Ser Ala Ser 
            100                 105                 110


Pro Ser Pro Pro Ala Arg Arg Arg Arg Arg Cys Leu Gly 
        115                 120                 125


<210>  5324
<211>  2667
<212>  DNA
<213>  Homo sapiens

<400>  5324
cgtgcgccgg cctggagggg ctgggaggcg tccggttttc agcagaggat tttgcagttc     60

ccaaggggac aggaaatgga gcctgtaatt tcggttgcag agagggggat ggccgacact    120

cttattttct gtatcgtttc ttcctcccag ttagtgcgct gcaggatttg tgaaaatcca    180

tcttgaggac tctcctagat aaaatcaaag acaaaattaa agagagagac aaagaaaaag    240

aaagagaaaa aaagaaacat aaagtaatga atgagatcaa gaaagagaat ggagaagtaa    300

agattttgct gaaaagtggg aaggagaaac caaaaacaaa tatagaagac ttacaaatta    360

aaaaggtaaa gaagaaaaag aaaaagaaac acaaagagaa tgaaaaacgg aagcgtccga    420

aaatgtatag caaatctatt cagaccatct gctcaggatt gctaactgat gttgaagatc    480

aagcagccaa aggcatccta aatgataaca taaaagatta cgttgggaag aatttggata    540

ccaagaacta tgattccaaa attccagaga acagtgagtt tccatttgtc tcattaaagg    600

agccacgagt tcagaataac ctcaaaaggt tggacacttt ggaatttaaa caactcattc    660

atatagagca ccagcctaat ggaggtgcat cggttatcca tgcctacagt aacgaactct    720

cccacctgtc tcctatggag atggagaggt ttgcagaaga gtttgtgggt ctagtgttca    780

gtgaaaatga aaactctgca gctttctacg tgatgggtat tgttcatggg gcagctactt    840

atttacctga ctttttagac tatttttcat ttaattttcc caattcacca gtgaaaatgg    900

agatattggg aaagaaagat atagagacaa cgactatgtc caattttcat gctcaggtaa    960

aaagaacgta ttctcatggt acttacagag ctggcccaat gagacaaata agcttggtgg   1020

gagcagttga tgaagaagta ggagattatt tccctgagtt ccttgacatg ttggaagagt   1080

caccattttt aaaatgtaca ctgccatggg ggacgctatc tagtctaaaa ttacagagtc   1140

gaaaagatag tgatgatggt cccatcatgt gggttcgtcc aggagaacaa atgatccctg   1200

tggctgatat gccaaagtca cctttcaaaa ggaaaagaac taccaatgaa ataaaaaatc   1260

ttcagtacct acctcgaaca agtgagcccc gtgagatgct ctttgaagac aggacaagag   1320

ctcatgcaga tcatatagga caaggttttg aacgacagac tacagctgct gttggagtgc   1380

tgaaggctgt gcactgtgga gagtggcctg atcaaccccg tataaccaaa gatgtaattt   1440

gttttcatgc tgaagatttc ttagaagtag ttcaacgaat gcagttagat ttacatgaac   1500

ctccactgtc ccagtgtgtc caatgggttg atgatgcaaa actgaatcaa ctgaggaggg   1560

aaggcattcg ctatgccagg attcagctat atgataatga catttatttt attccaagga   1620

atgttgttca tcagttcaag acagtttcag ctgtatgcag tttagcatgg catattcggc   1680

tcaaattata tcactcagag gaggacactt ctcagaatac agctactcat gaaacaggca   1740

catcatcaga ttccacatca tctgttcttg gacctcacac tgacaacatg atttgtgctg   1800

taagcaaagc ctccttggat tctgtttttt cagataaact tcattctaaa tatgaattac   1860

agcagattaa acatgaacct attgcatctg taagaatcaa ggaagaacct gtgaatgtta   1920

atattcctga aaagactaca gcactgaata atatggatgg caagaatgtt aaagcaaaat   1980

tggatcatgt tcaatttgca gaatttaaga ttgacatgga ttctaaattt gaaaatagca   2040

acaaagattt aaaggaagaa ttgtgccctg gaaatctaag tctagttgat acaaggcaac   2100

acagttcagc acattcaaat caagataaaa aagacgatga cattttgtgc taaatttgca   2160

tataccatct aaaatccttt tttaaaaaaa tttaatgtaa taaagattca tgaattctga   2220

aagcaagcca aggacttgct cctatgtctg ttacaaaaca tagtttatgt agctttgtaa   2280

cattcctcag tgcctgtcca taactgtgaa gtattaagca cttagggcca gatgcactgt   2340

aaacattgca ggtttaaaca taaaggagtc tttaaaaaaa aatcatttac gttggaattt   2400

taggttttag aatagagctg acattaacat atatatatat atataaatat atatatatat   2460

tttgtaatat gagccagaat tctttttcaa caatttaaag cttttccata gagcttattt   2520

atatcctttt ttttcatttt aaatgtgtca gcactgtagt gtaaatagct tttaaatatc   2580

tttttagtgt gatttatact gaaatgtgag ccacttaata aaggttcata tgttcatatt   2640

aataaatatg ttttctgttg agtctgt                                       2667


<210>  5325
<211>  628
<212>  PRT
<213>  Homo sapiens

<400>  5325

Met Asn Glu Ile Lys Lys Glu Asn Gly Glu Val Lys Ile Leu Leu Lys 
1               5                   10                  15


Ser Gly Lys Glu Lys Pro Lys Thr Asn Ile Glu Asp Leu Gln Ile Lys 
            20                  25                  30


Lys Val Lys Lys Lys Lys Lys Lys Lys His Lys Glu Asn Glu Lys Arg 
        35                  40                  45


Lys Arg Pro Lys Met Tyr Ser Lys Ser Ile Gln Thr Ile Cys Ser Gly 
    50                  55                  60


Leu Leu Thr Asp Val Glu Asp Gln Ala Ala Lys Gly Ile Leu Asn Asp 
65                  70                  75                  80


Asn Ile Lys Asp Tyr Val Gly Lys Asn Leu Asp Thr Lys Asn Tyr Asp 
                85                  90                  95


Ser Lys Ile Pro Glu Asn Ser Glu Phe Pro Phe Val Ser Leu Lys Glu 
            100                 105                 110


Pro Arg Val Gln Asn Asn Leu Lys Arg Leu Asp Thr Leu Glu Phe Lys 
        115                 120                 125


Gln Leu Ile His Ile Glu His Gln Pro Asn Gly Gly Ala Ser Val Ile 
    130                 135                 140


His Ala Tyr Ser Asn Glu Leu Ser His Leu Ser Pro Met Glu Met Glu 
145                 150                 155                 160


Arg Phe Ala Glu Glu Phe Val Gly Leu Val Phe Ser Glu Asn Glu Asn 
                165                 170                 175


Ser Ala Ala Phe Tyr Val Met Gly Ile Val His Gly Ala Ala Thr Tyr 
            180                 185                 190


Leu Pro Asp Phe Leu Asp Tyr Phe Ser Phe Asn Phe Pro Asn Ser Pro 
        195                 200                 205


Val Lys Met Glu Ile Leu Gly Lys Lys Asp Ile Glu Thr Thr Thr Met 
    210                 215                 220


Ser Asn Phe His Ala Gln Val Lys Arg Thr Tyr Ser His Gly Thr Tyr 
225                 230                 235                 240


Arg Ala Gly Pro Met Arg Gln Ile Ser Leu Val Gly Ala Val Asp Glu 
                245                 250                 255


Glu Val Gly Asp Tyr Phe Pro Glu Phe Leu Asp Met Leu Glu Glu Ser 
            260                 265                 270


Pro Phe Leu Lys Cys Thr Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys 
        275                 280                 285


Leu Gln Ser Arg Lys Asp Ser Asp Asp Gly Pro Ile Met Trp Val Arg 
    290                 295                 300


Pro Gly Glu Gln Met Ile Pro Val Ala Asp Met Pro Lys Ser Pro Phe 
305                 310                 315                 320


Lys Arg Lys Arg Thr Thr Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro 
                325                 330                 335


Arg Thr Ser Glu Pro Arg Glu Met Leu Phe Glu Asp Arg Thr Arg Ala 
            340                 345                 350


His Ala Asp His Ile Gly Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala 
        355                 360                 365


Val Gly Val Leu Lys Ala Val His Cys Gly Glu Trp Pro Asp Gln Pro 
    370                 375                 380


Arg Ile Thr Lys Asp Val Ile Cys Phe His Ala Glu Asp Phe Leu Glu 
385                 390                 395                 400


Val Val Gln Arg Met Gln Leu Asp Leu His Glu Pro Pro Leu Ser Gln 
                405                 410                 415


Cys Val Gln Trp Val Asp Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu 
            420                 425                 430


Gly Ile Arg Tyr Ala Arg Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe 
        435                 440                 445


Ile Pro Arg Asn Val Val His Gln Phe Lys Thr Val Ser Ala Val Cys 
    450                 455                 460


Ser Leu Ala Trp His Ile Arg Leu Lys Leu Tyr His Ser Glu Glu Asp 
465                 470                 475                 480


Thr Ser Gln Asn Thr Ala Thr His Glu Thr Gly Thr Ser Ser Asp Ser 
                485                 490                 495


Thr Ser Ser Val Leu Gly Pro His Thr Asp Asn Met Ile Cys Ala Val 
            500                 505                 510


Ser Lys Ala Ser Leu Asp Ser Val Phe Ser Asp Lys Leu His Ser Lys 
        515                 520                 525


Tyr Glu Leu Gln Gln Ile Lys His Glu Pro Ile Ala Ser Val Arg Ile 
    530                 535                 540


Lys Glu Glu Pro Val Asn Val Asn Ile Pro Glu Lys Thr Thr Ala Leu 
545                 550                 555                 560


Asn Asn Met Asp Gly Lys Asn Val Lys Ala Lys Leu Asp His Val Gln 
                565                 570                 575


Phe Ala Glu Phe Lys Ile Asp Met Asp Ser Lys Phe Glu Asn Ser Asn 
            580                 585                 590


Lys Asp Leu Lys Glu Glu Leu Cys Pro Gly Asn Leu Ser Leu Val Asp 
        595                 600                 605


Thr Arg Gln His Ser Ser Ala His Ser Asn Gln Asp Lys Lys Asp Asp 
    610                 615                 620


Asp Ile Leu Cys 
625


<210>  5326
<211>  2872
<212>  DNA
<213>  Homo sapiens

<400>  5326
cgtgcgccgg cctggagggg ctgggaggcg tccggttttc agcagaggat tttgcagttc     60

ccaaggggac aggaaatgga gcctgtaatt tcggttgcag agagggggat ggccgacact    120

cttattttct gtatcgtttc ttcctcccag ttagtgcgct gcaggatttg tgaaaatcca    180

tcttgaggac tctcctagat aaaatcaaag acaaaattaa agagagagac aaagaaaaag    240

aaagagaaaa aaagaaacat aaagtaatga atgagatcaa gaaagagaat ggagaagtaa    300

agattttgct gaaaagtggg aaggagaaac caaaaacaaa tatagaagac ttacaaatta    360

aaaaggtaaa gaagaaaaag aaaaagaaac acaaagagaa tgaaaaacgg aagcgtccga    420

aaatgtatag caaatctatt cagaccatct gctcaggatt gctaactgat gttgaagatc    480

aagcagccaa aggcatccta aatgataaca taaaagatta cgttgggaag aatttggata    540

ccaagaacta tgattccaaa attccagaga acagtgagtt tccatttgtc tcattaaagg    600

agccacgagt tcagaataac ctcaaaaggt tggacacttt ggaatttaaa caactcattc    660

atatagagca ccagcctaat ggaggtgcat cggttatcca tgcctacagt aacgaactct    720

cccacctgtc tcctatggag atggagaggt ttgcagaaga gtttgtgggt ctagtgttca    780

gtgaaaatga aaactctgca gctttctacg tgatgggtat tgttcatggg gcagctactt    840

atttacctga ctttttagac tatttttcat ttaattttcc caattcacca gtgaaaatgg    900

agatattggg aaagaaagat atagagacaa cgactatgtc caattttcat gctcaggtaa    960

aaagaacgta ttctcatggt acttacagag ctggcccaat gagacaaata agcttggtgg   1020

gagcagttga tgaagaagta ggagattatt tccctgagtt ccttgacatg ttggaagagt   1080

caccattttt aaaatgtaca ctgccatggg ggacgctatc tagtctaaaa ttacagagtc   1140

gaaaagatag tgatgatggt cccatcatgt gggttcgtcc aggagaacaa atgatccctg   1200

tggctgatat gccaaagtca cctttcaaaa ggaaaagaac taccaatgaa ataaaaaatc   1260

ttcagtacct acctcgaaca agtgagcccc gtgagatgct ctttgaagac aggacaagag   1320

ctcatgcaga tcatatagga caaggttttg aacgacagac tacagctgct gttggagtgc   1380

tgaaggctgt gcactgtgga gagtggcctg atcaaccccg tataaccaaa gatgtaattt   1440

gttttcatgc tgaagatttc ttagaagtag ttcaacgaat gcagttagat ttacatgaac   1500

ctccactgtc ccagtgtgtc caatgggttg atgatgcaaa actgaatcaa ctgaggaggg   1560

aaggcattcg ctatgccagg attcagctat atgataatga catttatttt attccaagga   1620

atgttgttca tcagttcaag acagtttcag ctgtatgcag tttagcatgg catattcggc   1680

tcaaattata tcactcagag gaggacactt ctcagaatac agctactcat gaaacaggca   1740

catcatcaga ttccacatca tctgttcttg gacctcacac tgacaacatg atttgtgctg   1800

taagcaaagc ctccttggat tctgtttttt cagataaact tcattctaaa tatgaattac   1860

agcagattaa acatgaacct attgcatctg taagaatcaa ggaagaacct gtgaatgtta   1920

atattcctga aaagactaca gcactgaata atatggatgg caagaatgtt aaagcaaaat   1980

tggatcatgt tcaatttgca gaatttaaga ttgacatgga ttctaaattt gaaaatagca   2040

acaaagattt aaaggaagaa ttgtgccctg gaaatctaag tctagttgat acaaggcaac   2100

acagttcagc acattcaaat caagataaaa aagacgatga cattttgtgc taaatttgca   2160

tataccatct aaaatccttt tttaaaaaaa tttaatgtaa taaagattca tgaattctga   2220

aagcaagcca aggacttgct cctatgtctg ttacaaaaca tagtttatgt agctttgtaa   2280

cattcctcag tgcctgtcca taactgtgaa gtattaagca cttagggcca gatgcactgt   2340

aaacattgca ggtttaaaca taaaggagtc tttaaaaaaa aatcatttac gttggaattt   2400

taggttttag aatagagctg acattaacat atatatatat atataaatat atatatatat   2460

tttgtaatat gagccagaat tctttttcaa caatttaaag cttttccata gagcttattt   2520

atatcctttt ttttcatttt aaatgtgtca gcactgtagt gtaaatagct tttaaatatc   2580

tttttagtgt gatttatact gaaatgtgag ccacttaata aaggttcata tgttcatatt   2640

aataaatatg ttttctgttg agtctgtaaa gacaaactga caattcattt aagtcatttg   2700

ataatgattc tctgctggta tatctattta gtgtggtatt gtagtgcaaa tgtacgtaat   2760

tcaaatctag taaatattta agttcctcac actgtgcagg cttttttttt tttttctttt   2820

tttctttttt ttgatacgga gtttcattct gtcaccaggc tggagttcag tg           2872


<210>  5327
<211>  628
<212>  PRT
<213>  Homo sapiens

<400>  5327

Met Asn Glu Ile Lys Lys Glu Asn Gly Glu Val Lys Ile Leu Leu Lys 
1               5                   10                  15


Ser Gly Lys Glu Lys Pro Lys Thr Asn Ile Glu Asp Leu Gln Ile Lys 
            20                  25                  30


Lys Val Lys Lys Lys Lys Lys Lys Lys His Lys Glu Asn Glu Lys Arg 
        35                  40                  45


Lys Arg Pro Lys Met Tyr Ser Lys Ser Ile Gln Thr Ile Cys Ser Gly 
    50                  55                  60


Leu Leu Thr Asp Val Glu Asp Gln Ala Ala Lys Gly Ile Leu Asn Asp 
65                  70                  75                  80


Asn Ile Lys Asp Tyr Val Gly Lys Asn Leu Asp Thr Lys Asn Tyr Asp 
                85                  90                  95


Ser Lys Ile Pro Glu Asn Ser Glu Phe Pro Phe Val Ser Leu Lys Glu 
            100                 105                 110


Pro Arg Val Gln Asn Asn Leu Lys Arg Leu Asp Thr Leu Glu Phe Lys 
        115                 120                 125


Gln Leu Ile His Ile Glu His Gln Pro Asn Gly Gly Ala Ser Val Ile 
    130                 135                 140


His Ala Tyr Ser Asn Glu Leu Ser His Leu Ser Pro Met Glu Met Glu 
145                 150                 155                 160


Arg Phe Ala Glu Glu Phe Val Gly Leu Val Phe Ser Glu Asn Glu Asn 
                165                 170                 175


Ser Ala Ala Phe Tyr Val Met Gly Ile Val His Gly Ala Ala Thr Tyr 
            180                 185                 190


Leu Pro Asp Phe Leu Asp Tyr Phe Ser Phe Asn Phe Pro Asn Ser Pro 
        195                 200                 205


Val Lys Met Glu Ile Leu Gly Lys Lys Asp Ile Glu Thr Thr Thr Met 
    210                 215                 220


Ser Asn Phe His Ala Gln Val Lys Arg Thr Tyr Ser His Gly Thr Tyr 
225                 230                 235                 240


Arg Ala Gly Pro Met Arg Gln Ile Ser Leu Val Gly Ala Val Asp Glu 
                245                 250                 255


Glu Val Gly Asp Tyr Phe Pro Glu Phe Leu Asp Met Leu Glu Glu Ser 
            260                 265                 270


Pro Phe Leu Lys Cys Thr Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys 
        275                 280                 285


Leu Gln Ser Arg Lys Asp Ser Asp Asp Gly Pro Ile Met Trp Val Arg 
    290                 295                 300


Pro Gly Glu Gln Met Ile Pro Val Ala Asp Met Pro Lys Ser Pro Phe 
305                 310                 315                 320


Lys Arg Lys Arg Thr Thr Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro 
                325                 330                 335


Arg Thr Ser Glu Pro Arg Glu Met Leu Phe Glu Asp Arg Thr Arg Ala 
            340                 345                 350


His Ala Asp His Ile Gly Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala 
        355                 360                 365


Val Gly Val Leu Lys Ala Val His Cys Gly Glu Trp Pro Asp Gln Pro 
    370                 375                 380


Arg Ile Thr Lys Asp Val Ile Cys Phe His Ala Glu Asp Phe Leu Glu 
385                 390                 395                 400


Val Val Gln Arg Met Gln Leu Asp Leu His Glu Pro Pro Leu Ser Gln 
                405                 410                 415


Cys Val Gln Trp Val Asp Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu 
            420                 425                 430


Gly Ile Arg Tyr Ala Arg Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe 
        435                 440                 445


Ile Pro Arg Asn Val Val His Gln Phe Lys Thr Val Ser Ala Val Cys 
    450                 455                 460


Ser Leu Ala Trp His Ile Arg Leu Lys Leu Tyr His Ser Glu Glu Asp 
465                 470                 475                 480


Thr Ser Gln Asn Thr Ala Thr His Glu Thr Gly Thr Ser Ser Asp Ser 
                485                 490                 495


Thr Ser Ser Val Leu Gly Pro His Thr Asp Asn Met Ile Cys Ala Val 
            500                 505                 510


Ser Lys Ala Ser Leu Asp Ser Val Phe Ser Asp Lys Leu His Ser Lys 
        515                 520                 525


Tyr Glu Leu Gln Gln Ile Lys His Glu Pro Ile Ala Ser Val Arg Ile 
    530                 535                 540


Lys Glu Glu Pro Val Asn Val Asn Ile Pro Glu Lys Thr Thr Ala Leu 
545                 550                 555                 560


Asn Asn Met Asp Gly Lys Asn Val Lys Ala Lys Leu Asp His Val Gln 
                565                 570                 575


Phe Ala Glu Phe Lys Ile Asp Met Asp Ser Lys Phe Glu Asn Ser Asn 
            580                 585                 590


Lys Asp Leu Lys Glu Glu Leu Cys Pro Gly Asn Leu Ser Leu Val Asp 
        595                 600                 605


Thr Arg Gln His Ser Ser Ala His Ser Asn Gln Asp Lys Lys Asp Asp 
    610                 615                 620


Asp Ile Leu Cys 
625


<210>  5328
<211>  1412
<212>  DNA
<213>  Homo sapiens

<400>  5328
cagaattgaa tcaacagctt ctgctcccac ccccctcaat tctttggctc taataatgat     60

cctgtttttg tattttcttc acattggtgc tgatacaagc taaaaatatc tgtatctcca    120

tatttatggt ggatcactat gaaggtaaaa agaacgtatt ctcatggtac ttacagagct    180

ggcccaatga gacaaataag cttggtggga gcagttgatg aagaagtagg agattatttc    240

cctgagttcc ttgacatgtt ggaagagtca ccatttttaa aatgtacact gccatggggg    300

acgctatcta gtctaaaatt acagagtcga aaagatagtg atgatggtcc catcatgtgg    360

gttcgtccag gagaacaaat gatccctgtg gctgatatgc caaagtcacc tttcaaaagg    420

aaaagaacta ccaatgaaat aaaaaatctt cagtacctac ctcgaacaag tgagccccgt    480

gagatgctct ttgaagacag gacaagagct catgcagatc atataggaca aggttttgaa    540

cgacagacta cagctgctgt tggagtgctg aaggctgtgc actgtggaga gtggcctgat    600

caaccccgta taaccaaaga tgtaatttgt tttcatgctg aagatttctt agaagtagtt    660

caacgaatgc agttagattt acatgaacct ccactgtccc agtgtgtcca atgggttgat    720

gatgcaaaac tgaatcaact gaggagggaa ggcattcgct atgccaggat tcagctatat    780

gataatgaca tttattttat tccaaggaat gttgttcatc agttcaagac agtttcagct    840

gtatgcagtt tagcatggca tattcggctc aaattatatc actcagagga ggacacttct    900

cagaatacag ctactcatga aacaggcaca tcatcagatt ccacatcatc tgttcttgga    960

cctcacactg acaacatgat ttgtgctgta agcaaagcct ccttggattc tgttttttca   1020

gataaacttc attctaaata tgaattacag cagattaaac atgaacctat tgcatctgta   1080

agaatcaagg aagaacctgt gaatgttaat attcctgaaa agactacagc actgaataat   1140

atggatggca agaatgttaa agcaaaattg gatcatgttc aatttgcaga atttaagatt   1200

gacatggatt ctaaatttga aaatagcaac aaagatttaa aggaagaatt gtgccctgga   1260

aatctaagtc tagttgatac aaggcaacac agttcagcac attcaaatca agataaaaaa   1320

gacgatgaca ttttgtgcta aatttgcata taccatctaa aatccttttt taaaaaaatt   1380

taatgtaata aagattcatg aattctgaaa gc                                 1412


<210>  5329
<211>  400
<212>  PRT
<213>  Homo sapiens

<400>  5329

Met Lys Val Lys Arg Thr Tyr Ser His Gly Thr Tyr Arg Ala Gly Pro 
1               5                   10                  15


Met Arg Gln Ile Ser Leu Val Gly Ala Val Asp Glu Glu Val Gly Asp 
            20                  25                  30


Tyr Phe Pro Glu Phe Leu Asp Met Leu Glu Glu Ser Pro Phe Leu Lys 
        35                  40                  45


Cys Thr Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys Leu Gln Ser Arg 
    50                  55                  60


Lys Asp Ser Asp Asp Gly Pro Ile Met Trp Val Arg Pro Gly Glu Gln 
65                  70                  75                  80


Met Ile Pro Val Ala Asp Met Pro Lys Ser Pro Phe Lys Arg Lys Arg 
                85                  90                  95


Thr Thr Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro Arg Thr Ser Glu 
            100                 105                 110


Pro Arg Glu Met Leu Phe Glu Asp Arg Thr Arg Ala His Ala Asp His 
        115                 120                 125


Ile Gly Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala Val Gly Val Leu 
    130                 135                 140


Lys Ala Val His Cys Gly Glu Trp Pro Asp Gln Pro Arg Ile Thr Lys 
145                 150                 155                 160


Asp Val Ile Cys Phe His Ala Glu Asp Phe Leu Glu Val Val Gln Arg 
                165                 170                 175


Met Gln Leu Asp Leu His Glu Pro Pro Leu Ser Gln Cys Val Gln Trp 
            180                 185                 190


Val Asp Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu Gly Ile Arg Tyr 
        195                 200                 205


Ala Arg Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe Ile Pro Arg Asn 
    210                 215                 220


Val Val His Gln Phe Lys Thr Val Ser Ala Val Cys Ser Leu Ala Trp 
225                 230                 235                 240


His Ile Arg Leu Lys Leu Tyr His Ser Glu Glu Asp Thr Ser Gln Asn 
                245                 250                 255


Thr Ala Thr His Glu Thr Gly Thr Ser Ser Asp Ser Thr Ser Ser Val 
            260                 265                 270


Leu Gly Pro His Thr Asp Asn Met Ile Cys Ala Val Ser Lys Ala Ser 
        275                 280                 285


Leu Asp Ser Val Phe Ser Asp Lys Leu His Ser Lys Tyr Glu Leu Gln 
    290                 295                 300


Gln Ile Lys His Glu Pro Ile Ala Ser Val Arg Ile Lys Glu Glu Pro 
305                 310                 315                 320


Val Asn Val Asn Ile Pro Glu Lys Thr Thr Ala Leu Asn Asn Met Asp 
                325                 330                 335


Gly Lys Asn Val Lys Ala Lys Leu Asp His Val Gln Phe Ala Glu Phe 
            340                 345                 350


Lys Ile Asp Met Asp Ser Lys Phe Glu Asn Ser Asn Lys Asp Leu Lys 
        355                 360                 365


Glu Glu Leu Cys Pro Gly Asn Leu Ser Leu Val Asp Thr Arg Gln His 
    370                 375                 380


Ser Ser Ala His Ser Asn Gln Asp Lys Lys Asp Asp Asp Ile Leu Cys 
385                 390                 395                 400


<210>  5330
<211>  1855
<212>  DNA
<213>  Homo sapiens

<400>  5330
cagaattgaa tcaacagctt ctgctcccac ccccctcaat tctttggctc taataatgat     60

cctgtttttg tattttcttc acattggtgc tgatacaagc taaaaatatc tgtatctcca    120

tatttatggt ggatcactat gaaggtaaaa agaacgtatt ctcatggtac ttacagagct    180

ggcccaatga gacaaataag cttggtggga gcagttgatg aagaagtagg agattatttc    240

cctgagttcc ttgacatgtt ggaagagtca ccatttttaa aatgtacact gccatggggg    300

acgctatcta gtctaaaatt acagagtcga aaagatagtg atgatggtcc catcatgtgg    360

gttcgtccag gagaacaaat gatccctgtg gctgatatgc caaagtcacc tttcaaaagg    420

aaaagaacta ccaatgaaat aaaaaatctt cagtacctac ctcgaacaag tgagccccgt    480

gagatgctct ttgaagacag gacaagagct catgcagatc atataggaca aggttttgaa    540

cgacagacta cagctgctgt tggagtgctg aaggctgtgc actgtggaga gtggcctgat    600

caaccccgta taaccaaaga tgtaatttgt tttcatgctg aagatttctt agaagtagtt    660

caacgaatgc agttagattt acatgaacct ccactgtccc agtgtgtcca atgggttgat    720

gatgcaaaac tgaatcaact gaggagggaa ggcattcgct atgccaggat tcagctatat    780

gataatgaca tttattttat tccaaggaat gttgttcatc agttcaagac agtttcagct    840

gtatgcagtt tagcatggca tattcggctc aaattatatc actcagagga ggacacttct    900

cagaatacag ctactcatga aacaggcaca tcatcagatt ccacatcatc tgttcttgga    960

cctcacactg acaacatgat ttgtgctgta agcaaagcct ccttggattc tgttttttca   1020

gataaacttc attctaaata tgaattacag cagattaaac atgaacctat tgcatctgta   1080

agaatcaagg aagaacctgt gaatgttaat attcctgaaa agactacagc actgaataat   1140

atggatggca agaatgttaa agcaaaattg gatcatgttc aatttgcaga atttaagatt   1200

gacatggatt ctaaatttga aaatagcaac aaagatttaa aggaagaatt gtgccctgga   1260

aatctaagtc tagttgatac aaggcaacac agttcagcac attcaaatca agataaaaaa   1320

gacgatgaca ttttgtgcta aatttgcata taccatctaa aatccttttt taaaaaaatt   1380

taatgtaata aagattcatg aattctgaaa gcaagccaag gacttgctcc tatgtctgtt   1440

acaaaacata gtttatgtag ctttgtaaca ttcctcagtg cctgtccata actgtgaagt   1500

attaagcact tagggccaga tgcactgtaa acattgcagg tttaaacata aaggagtctt   1560

taaaaaaaaa tcatttacgt tggaatttta ggttttagaa tagagctgac attaacatat   1620

atatatatat ataaatatat atatatattt tgtaatatga gccagaattc tttttcaaca   1680

atttaaagct tttccataga gcttatttat atcctttttt ttcattttaa atgtgtcagc   1740

actgtagtgt aaatagcttt taaatatctt tttagtgtga tttatactga aatgtgagcc   1800

acttaataaa ggttcatatg ttcatattaa taaatatgtt ttctgttgag tctgt        1855


<210>  5331
<211>  400
<212>  PRT
<213>  Homo sapiens

<400>  5331

Met Lys Val Lys Arg Thr Tyr Ser His Gly Thr Tyr Arg Ala Gly Pro 
1               5                   10                  15


Met Arg Gln Ile Ser Leu Val Gly Ala Val Asp Glu Glu Val Gly Asp 
            20                  25                  30


Tyr Phe Pro Glu Phe Leu Asp Met Leu Glu Glu Ser Pro Phe Leu Lys 
        35                  40                  45


Cys Thr Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys Leu Gln Ser Arg 
    50                  55                  60


Lys Asp Ser Asp Asp Gly Pro Ile Met Trp Val Arg Pro Gly Glu Gln 
65                  70                  75                  80


Met Ile Pro Val Ala Asp Met Pro Lys Ser Pro Phe Lys Arg Lys Arg 
                85                  90                  95


Thr Thr Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro Arg Thr Ser Glu 
            100                 105                 110


Pro Arg Glu Met Leu Phe Glu Asp Arg Thr Arg Ala His Ala Asp His 
        115                 120                 125


Ile Gly Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala Val Gly Val Leu 
    130                 135                 140


Lys Ala Val His Cys Gly Glu Trp Pro Asp Gln Pro Arg Ile Thr Lys 
145                 150                 155                 160


Asp Val Ile Cys Phe His Ala Glu Asp Phe Leu Glu Val Val Gln Arg 
                165                 170                 175


Met Gln Leu Asp Leu His Glu Pro Pro Leu Ser Gln Cys Val Gln Trp 
            180                 185                 190


Val Asp Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu Gly Ile Arg Tyr 
        195                 200                 205


Ala Arg Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe Ile Pro Arg Asn 
    210                 215                 220


Val Val His Gln Phe Lys Thr Val Ser Ala Val Cys Ser Leu Ala Trp 
225                 230                 235                 240


His Ile Arg Leu Lys Leu Tyr His Ser Glu Glu Asp Thr Ser Gln Asn 
                245                 250                 255


Thr Ala Thr His Glu Thr Gly Thr Ser Ser Asp Ser Thr Ser Ser Val 
            260                 265                 270


Leu Gly Pro His Thr Asp Asn Met Ile Cys Ala Val Ser Lys Ala Ser 
        275                 280                 285


Leu Asp Ser Val Phe Ser Asp Lys Leu His Ser Lys Tyr Glu Leu Gln 
    290                 295                 300


Gln Ile Lys His Glu Pro Ile Ala Ser Val Arg Ile Lys Glu Glu Pro 
305                 310                 315                 320


Val Asn Val Asn Ile Pro Glu Lys Thr Thr Ala Leu Asn Asn Met Asp 
                325                 330                 335


Gly Lys Asn Val Lys Ala Lys Leu Asp His Val Gln Phe Ala Glu Phe 
            340                 345                 350


Lys Ile Asp Met Asp Ser Lys Phe Glu Asn Ser Asn Lys Asp Leu Lys 
        355                 360                 365


Glu Glu Leu Cys Pro Gly Asn Leu Ser Leu Val Asp Thr Arg Gln His 
    370                 375                 380


Ser Ser Ala His Ser Asn Gln Asp Lys Lys Asp Asp Asp Ile Leu Cys 
385                 390                 395                 400


<210>  5332
<211>  2060
<212>  DNA
<213>  Homo sapiens

<400>  5332
cagaattgaa tcaacagctt ctgctcccac ccccctcaat tctttggctc taataatgat     60

cctgtttttg tattttcttc acattggtgc tgatacaagc taaaaatatc tgtatctcca    120

tatttatggt ggatcactat gaaggtaaaa agaacgtatt ctcatggtac ttacagagct    180

ggcccaatga gacaaataag cttggtggga gcagttgatg aagaagtagg agattatttc    240

cctgagttcc ttgacatgtt ggaagagtca ccatttttaa aatgtacact gccatggggg    300

acgctatcta gtctaaaatt acagagtcga aaagatagtg atgatggtcc catcatgtgg    360

gttcgtccag gagaacaaat gatccctgtg gctgatatgc caaagtcacc tttcaaaagg    420

aaaagaacta ccaatgaaat aaaaaatctt cagtacctac ctcgaacaag tgagccccgt    480

gagatgctct ttgaagacag gacaagagct catgcagatc atataggaca aggttttgaa    540

cgacagacta cagctgctgt tggagtgctg aaggctgtgc actgtggaga gtggcctgat    600

caaccccgta taaccaaaga tgtaatttgt tttcatgctg aagatttctt agaagtagtt    660

caacgaatgc agttagattt acatgaacct ccactgtccc agtgtgtcca atgggttgat    720

gatgcaaaac tgaatcaact gaggagggaa ggcattcgct atgccaggat tcagctatat    780

gataatgaca tttattttat tccaaggaat gttgttcatc agttcaagac agtttcagct    840

gtatgcagtt tagcatggca tattcggctc aaattatatc actcagagga ggacacttct    900

cagaatacag ctactcatga aacaggcaca tcatcagatt ccacatcatc tgttcttgga    960

cctcacactg acaacatgat ttgtgctgta agcaaagcct ccttggattc tgttttttca   1020

gataaacttc attctaaata tgaattacag cagattaaac atgaacctat tgcatctgta   1080

agaatcaagg aagaacctgt gaatgttaat attcctgaaa agactacagc actgaataat   1140

atggatggca agaatgttaa agcaaaattg gatcatgttc aatttgcaga atttaagatt   1200

gacatggatt ctaaatttga aaatagcaac aaagatttaa aggaagaatt gtgccctgga   1260

aatctaagtc tagttgatac aaggcaacac agttcagcac attcaaatca agataaaaaa   1320

gacgatgaca ttttgtgcta aatttgcata taccatctaa aatccttttt taaaaaaatt   1380

taatgtaata aagattcatg aattctgaaa gcaagccaag gacttgctcc tatgtctgtt   1440

acaaaacata gtttatgtag ctttgtaaca ttcctcagtg cctgtccata actgtgaagt   1500

attaagcact tagggccaga tgcactgtaa acattgcagg tttaaacata aaggagtctt   1560

taaaaaaaaa tcatttacgt tggaatttta ggttttagaa tagagctgac attaacatat   1620

atatatatat ataaatatat atatatattt tgtaatatga gccagaattc tttttcaaca   1680

atttaaagct tttccataga gcttatttat atcctttttt ttcattttaa atgtgtcagc   1740

actgtagtgt aaatagcttt taaatatctt tttagtgtga tttatactga aatgtgagcc   1800

acttaataaa ggttcatatg ttcatattaa taaatatgtt ttctgttgag tctgtaaaga   1860

caaactgaca attcatttaa gtcatttgat aatgattctc tgctggtata tctatttagt   1920

gtggtattgt agtgcaaatg tacgtaattc aaatctagta aatatttaag ttcctcacac   1980

tgtgcaggct tttttttttt tttctttttt tctttttttt gatacggagt ttcattctgt   2040

caccaggctg gagttcagtg                                               2060


<210>  5333
<211>  400
<212>  PRT
<213>  Homo sapiens

<400>  5333

Met Lys Val Lys Arg Thr Tyr Ser His Gly Thr Tyr Arg Ala Gly Pro 
1               5                   10                  15


Met Arg Gln Ile Ser Leu Val Gly Ala Val Asp Glu Glu Val Gly Asp 
            20                  25                  30


Tyr Phe Pro Glu Phe Leu Asp Met Leu Glu Glu Ser Pro Phe Leu Lys 
        35                  40                  45


Cys Thr Leu Pro Trp Gly Thr Leu Ser Ser Leu Lys Leu Gln Ser Arg 
    50                  55                  60


Lys Asp Ser Asp Asp Gly Pro Ile Met Trp Val Arg Pro Gly Glu Gln 
65                  70                  75                  80


Met Ile Pro Val Ala Asp Met Pro Lys Ser Pro Phe Lys Arg Lys Arg 
                85                  90                  95


Thr Thr Asn Glu Ile Lys Asn Leu Gln Tyr Leu Pro Arg Thr Ser Glu 
            100                 105                 110


Pro Arg Glu Met Leu Phe Glu Asp Arg Thr Arg Ala His Ala Asp His 
        115                 120                 125


Ile Gly Gln Gly Phe Glu Arg Gln Thr Thr Ala Ala Val Gly Val Leu 
    130                 135                 140


Lys Ala Val His Cys Gly Glu Trp Pro Asp Gln Pro Arg Ile Thr Lys 
145                 150                 155                 160


Asp Val Ile Cys Phe His Ala Glu Asp Phe Leu Glu Val Val Gln Arg 
                165                 170                 175


Met Gln Leu Asp Leu His Glu Pro Pro Leu Ser Gln Cys Val Gln Trp 
            180                 185                 190


Val Asp Asp Ala Lys Leu Asn Gln Leu Arg Arg Glu Gly Ile Arg Tyr 
        195                 200                 205


Ala Arg Ile Gln Leu Tyr Asp Asn Asp Ile Tyr Phe Ile Pro Arg Asn 
    210                 215                 220


Val Val His Gln Phe Lys Thr Val Ser Ala Val Cys Ser Leu Ala Trp 
225                 230                 235                 240


His Ile Arg Leu Lys Leu Tyr His Ser Glu Glu Asp Thr Ser Gln Asn 
                245                 250                 255


Thr Ala Thr His Glu Thr Gly Thr Ser Ser Asp Ser Thr Ser Ser Val 
            260                 265                 270


Leu Gly Pro His Thr Asp Asn Met Ile Cys Ala Val Ser Lys Ala Ser 
        275                 280                 285


Leu Asp Ser Val Phe Ser Asp Lys Leu His Ser Lys Tyr Glu Leu Gln 
    290                 295                 300


Gln Ile Lys His Glu Pro Ile Ala Ser Val Arg Ile Lys Glu Glu Pro 
305                 310                 315                 320


Val Asn Val Asn Ile Pro Glu Lys Thr Thr Ala Leu Asn Asn Met Asp 
                325                 330                 335


Gly Lys Asn Val Lys Ala Lys Leu Asp His Val Gln Phe Ala Glu Phe 
            340                 345                 350


Lys Ile Asp Met Asp Ser Lys Phe Glu Asn Ser Asn Lys Asp Leu Lys 
        355                 360                 365


Glu Glu Leu Cys Pro Gly Asn Leu Ser Leu Val Asp Thr Arg Gln His 
    370                 375                 380


Ser Ser Ala His Ser Asn Gln Asp Lys Lys Asp Asp Asp Ile Leu Cys 
385                 390                 395                 400


<210>  5334
<211>  1035
<212>  DNA
<213>  Homo sapiens

<400>  5334
aaaggtcggt tggtttgcac tggcggacaa atggtccaat taccgcggaa aagggacctc     60

tgaatccaga ttggcgtcct ctctacctat agggtaggct caggggcggt gagaaccagc    120

cccggatgtg ggcgcggcac tgaggtagaa ctgagagatc ctctaccgca gtcgtttgag    180

gaggcggaac tgaagttttt tcttaattat catgtgacgg gttctggatt taatgggggg    240

aaaagggcgg aaaaggacaa ggatccaaac tggcgaattt gctgatcttc gcgtccctct    300

ccgctttccg gccggcagcg ctgccagggt atatttcctt ttttccgatc ctgcaacagc    360

ctctttaaac tgtttaaatg agaatgtcct tggctcagag agtactactc acctggcttt    420

tcacactact cttcttgatc atgttggtgt tgaaactgga tgagaaagca ccttggaact    480

ggttcctcat attcattcca gtctggatat ttgatactat ccttcttgtc ctgctgattg    540

tgaaaatggc tgggcggtgt aagtctggct ttgaccctcg acatggatca cacaatatta    600

aaaaaaaagc ctggtacctc attgcaatgt tacttaaatt agccttctgc ctcgcactct    660

gtgctaaact ggaacagttt actaccatga atctatccta tgtcttcatt cctttatggg    720

ccttgctggc tggggcttta acagaactcg gatataatgt cttttttgtg agagactgac    780

ttctaagtac atcatctcct ttctattgct gttcaacaag ttaccattaa agtgttctga    840

atctgtcaag cttcaagaat accagagaac tgagggaaaa taccaaatgt agttttatac    900

tacttccata aaacaggatt ggtgaatcac ggacttctag tcaacctaca gcttaattat    960

tcagcatttg agttattgag atccttatta tctctatgta aataaagttt gttttggacc   1020

tcatttttct acatg                                                    1035


<210>  5335
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  5335

Met Gly Gly Lys Gly Arg Lys Arg Thr Arg Ile Gln Thr Gly Glu Phe 
1               5                   10                  15


Ala Asp Leu Arg Val Pro Leu Arg Phe Pro Ala Gly Ser Ala Ala Arg 
            20                  25                  30


Val Tyr Phe Leu Phe Ser Asp Pro Ala Thr Ala Ser Leu Asn Cys Leu 
        35                  40                  45


Asn Glu Asn Val Leu Gly Ser Glu Ser Thr Thr His Leu Ala Phe His 
    50                  55                  60


Thr Thr Leu Leu Asp His Val Gly Val Glu Thr Gly 
65                  70                  75


<210>  5336
<211>  674
<212>  DNA
<213>  Homo sapiens

<400>  5336
atcctccctg cccgcgcgca gtgactgcag gctccggcgc aaaatcctgc gggagagggg     60

gtggggcaac cctctggagg cagcgcgccc gcgggcagcc tcgttgtggc tccttgggct    120

ctgttggcgg cggcgctagc ttcggagtct cccgcgcgca cctcagccgc ctcctagcgg    180

cgcggcgctc gctcctacgc ctaaaatgac caatgtgtga tttcagtgga ataaatggcg    240

tccaaagtca cagatgctat agtctggtat caaaagaaga ttggagcata tgatcaacaa    300

atatgggaaa aatctgttga acagagagaa atcaaggggc taaggaataa accaaagaaa    360

acagcacatg tgaaaccaga cctcatagat gttgatcttg taagagggtc tgcatttgca    420

aaggcaaagc ctgaaagtcc ttggacttct ctgaccagaa agggaattgt tcgagttgta    480

tttttcccct ttttcttccg gtggtggtta caagtaacat caaaggtcat ctttttctgg    540

cttcttgtcc tttatcttct tcaaggtact ccttggccct ggattcaggc atggctggat    600

tgagaggctc ggataatatc ttcacttctt tttgctgtag actttggtct tgctggtcac    660

attcttaggt tggc                                                      674


<210>  5337
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  5337

Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile 
1               5                   10                  15


Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu 
            20                  25                  30


Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro 
        35                  40                  45


Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala 
    50                  55                  60


Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg 
65                  70                  75                  80


Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser 
                85                  90                  95


Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Gly Thr 
            100                 105                 110


Pro Trp Pro Trp Ile Gln Ala Trp Leu Asp 
        115                 120


<210>  5338
<211>  1852
<212>  DNA
<213>  Homo sapiens

<400>  5338
atcctccctg cccgcgcgca gtgactgcag gctccggcgc aaaatcctgc gggagagggg     60

gtggggcaac cctctggagg cagcgcgccc gcgggcagcc tcgttgtggc tccttgggct    120

ctgttggcgg cggcgctagc ttcggagtct cccgcgcgca cctcagccgc ctcctagcgg    180

cgcggcgctc gctcctacgc ctaaaatgac caatgtgtga tttcagtgga ataaatggcg    240

tccaaagtca cagatgctat agtctggtat caaaagaaga ttggagcata tgatcaacaa    300

atatgggaaa aatctgttga acagagagaa atcaaggggc taaggaataa accaaagaaa    360

acagcacatg tgaaaccaga cctcatagat gttgatcttg taagagggtc tgcatttgca    420

aaggcaaagc ctgaaagtcc ttggacttct ctgaccagaa agggaattgt tcgagttgta    480

tttttcccct ttttcttccg gtggtggtta caagtaacat caaaggtcat ctttttctgg    540

cttcttgtcc tttatcttct tcaagttgct gcaatagtat tattctgctc cacttctagc    600

ccacacagca tacctctgac agaggtgatt gggccgatat ggctgatgct gctcctggga    660

actgtgcatt gccagattgt ttccacaaga acacccaaac ctcctctaag tacagggggt    720

aaaagaagaa ggaaattaag aaaagcagcc catttggaag tacataggga aggagatggt    780

tctagtacca cagataacac acaagaggga gcagttcaga accacggtac aagcacctct    840

cacagcgttg gcactgtctt cagagatctc tggcatgctg ctttcttttt atcaggatca    900

aagaaagcaa agaattcaat tgataaatca actgaaactg acaatggcta tgtatccctt    960

gatgggaaga agactgttaa aagcggtgaa gatggaatac aaaaccatga acctcagtgt   1020

gaaactattc gaccagaaga gacagcctgg aacacaggaa cactgaggaa tggtcctagc   1080

aaagataccc aaaggacaat aacaaatgtc tctgatgaag tctccagtga ggaaggtcct   1140

gaaacaggat actcattacg tcgtcatgtg gacaggactt ctgaaggtgt tcttcggaat   1200

agaaagtcac accattataa gaaacattac cctaatgagg tatatacttt gtccttaagt   1260

gtatacatac gtatctattt tatatgttac taatttataa cttctttcaa caattaaaaa   1320

ttgttgaaat aaatatttca cattattatc aatatttatt attgttgtat gatctggatt   1380

tataaaatag cagttttagg tttacgtatt gcacatgtat tgatagatag ccacacattt   1440

gagctcattt tatgcattat ctttgaagac tcatacattg tttgttgttt gcttttaaag   1500

aagaacattc tggagagaga atctgcaaac tcctgtgttc actttttcca caatttgaaa   1560

ggctttatac atttgatcat agcaaagtta ttttaagtaa cttccttcat attgctgtca   1620

ccagttatta agtccccata cttcaaaatt cagttctttt ttctttgttt ctatttttcc   1680

ttattaatct ttattttctc taaacccttt tcaactatat catatctctt gagcttcaaa   1740

ttgtttaaat aaagaatttc attcaattgt attttcagtt tctaatctaa gggtagaaca   1800

tttggcttta aggcaaataa attacactgt ttatcacttt tttataaaca tt           1852


<210>  5339
<211>  352
<212>  PRT
<213>  Homo sapiens

<400>  5339

Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile 
1               5                   10                  15


Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu 
            20                  25                  30


Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro 
        35                  40                  45


Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala 
    50                  55                  60


Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg 
65                  70                  75                  80


Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser 
                85                  90                  95


Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Val Ala 
            100                 105                 110


Ala Ile Val Leu Phe Cys Ser Thr Ser Ser Pro His Ser Ile Pro Leu 
        115                 120                 125


Thr Glu Val Ile Gly Pro Ile Trp Leu Met Leu Leu Leu Gly Thr Val 
    130                 135                 140


His Cys Gln Ile Val Ser Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr 
145                 150                 155                 160


Gly Gly Lys Arg Arg Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val 
                165                 170                 175


His Arg Glu Gly Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly 
            180                 185                 190


Ala Val Gln Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val 
        195                 200                 205


Phe Arg Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys 
    210                 215                 220


Ala Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val 
225                 230                 235                 240


Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile Gln 
                245                 250                 255


Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr Ala Trp 
            260                 265                 270


Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr Gln Arg Thr 
        275                 280                 285


Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu Gly Pro Glu Thr 
    290                 295                 300


Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr Ser Glu Gly Val Leu 
305                 310                 315                 320


Arg Asn Arg Lys Ser His His Tyr Lys Lys His Tyr Pro Asn Glu Val 
                325                 330                 335


Tyr Thr Leu Ser Leu Ser Val Tyr Ile Arg Ile Tyr Phe Ile Cys Tyr 
            340                 345                 350


<210>  5340
<211>  1935
<212>  DNA
<213>  Homo sapiens

<400>  5340
atcctccctg cccgcgcgca gtgactgcag gctccggcgc aaaatcctgc gggagagggg     60

gtggggcaac cctctggagg cagcgcgccc gcgggcagcc tcgttgtggc tccttgggct    120

ctgttggcgg cggcgctagc ttcggagtct cccgcgcgca cctcagccgc ctcctagcgg    180

cgcggcgctc gctcctacgc ctaaaatgac caatgtgtga tttcagtgga ataaatggcg    240

tccaaagtca cagatgctat agtctggtat caaaagaaga ttggagcata tgatcaacaa    300

atatgggaaa aatctgttga acagagagaa atcaaggggc taaggaataa accaaagaaa    360

acagcacatg tgaaaccaga cctcatagat gttgatcttg taagagggtc tgcatttgca    420

aaggcaaagc ctgaaagtcc ttggacttct ctgaccagaa agggaattgt tcgagttgta    480

tttttcccct ttttcttccg gtggtggtta caagtaacat caaaggtcat ctttttctgg    540

cttcttgtcc tttatcttct tcaagttgct gcaatagtat tattctgctc cacttctagc    600

ccacacagca tacctctgac agaggtgatt gggccgatat ggctgatgct gctcctggga    660

actgtgcatt gccagattgt ttccacaaga acacccaaac ctcctctaag tacagggggt    720

aaaagaagaa ggaaattaag aaaagcagcc catttggaag tacataggga aggagatggt    780

tctagtacca cagataacac acaagaggga gcagttcaga accacggtac aagcacctct    840

cacagcgttg gcactgtctt cagagatctc tggcatgctg ctttcttttt atcaggatca    900

aagaaagcaa agaattcaat tgataaatca actgaaactg acaatggcta tgtatccctt    960

gatgggaaga agactgttaa aagcggtgaa gatggaatac aaaaccatga acctcagtgt   1020

gaaactattc gaccagaaga gacagcctgg aacacaggaa cactgaggaa tggtcctagc   1080

aaagataccc aaaggacaat aacaaatgtc tctgatgaag tctccagtga ggaaggtcct   1140

gaaacaggat actcattacg tcgtcatgtg gacaggactt ctgaaggtgt tcttcggaat   1200

agaaagtcac accattataa gaaacattac cctaatgagg acgcccctaa atcgggtact   1260

agttgcagct ctcgctgttc aagttccaga caggattctg agagtgcaag gccagaatct   1320

gaaacagaag atgtgttatg ggaagacttg ttacattgtg cagaatgcca ttcatcttgt   1380

accagtgaga cagatgtgga aaatcatcag attaatccat gtgtgaaaaa agaatataga   1440

gatgaccctt ttcatcagag tcatttgccc tggctccata gttcccaccc aggattagaa   1500

aaaataagtg ctatagtatg ggaaggtaat gattgtaaga aagcagacat gtctgtactt   1560

gaaatcagtg gaatgataat gaacagagtg aacagccata taccaggaat aggataccag   1620

atttttggaa atgcagtctc tctcatactg ggtttaactc catttgtttt ccgactttct   1680

caagctacag acttggaaca actcacagca cattctgctt cagaacttta tgtgattgca   1740

tttggttcta atgaagatgt catagttctt tctatggtta taataagttt tgtggttcgc   1800

gtgtctcttg tgtggatttt cttttttttg ctctgtgtag cagaaagaac ttataaacag   1860

gtgggtataa tgtagacttc cgaataagaa tattttatcg ttttcataat attaaaagta   1920

ttcctgaagt acttt                                                    1935


<210>  5341
<211>  546
<212>  PRT
<213>  Homo sapiens

<400>  5341

Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile 
1               5                   10                  15


Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu 
            20                  25                  30


Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro 
        35                  40                  45


Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala 
    50                  55                  60


Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg 
65                  70                  75                  80


Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser 
                85                  90                  95


Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Val Ala 
            100                 105                 110


Ala Ile Val Leu Phe Cys Ser Thr Ser Ser Pro His Ser Ile Pro Leu 
        115                 120                 125


Thr Glu Val Ile Gly Pro Ile Trp Leu Met Leu Leu Leu Gly Thr Val 
    130                 135                 140


His Cys Gln Ile Val Ser Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr 
145                 150                 155                 160


Gly Gly Lys Arg Arg Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val 
                165                 170                 175


His Arg Glu Gly Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly 
            180                 185                 190


Ala Val Gln Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val 
        195                 200                 205


Phe Arg Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys 
    210                 215                 220


Ala Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val 
225                 230                 235                 240


Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile Gln 
                245                 250                 255


Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr Ala Trp 
            260                 265                 270


Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr Gln Arg Thr 
        275                 280                 285


Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu Gly Pro Glu Thr 
    290                 295                 300


Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr Ser Glu Gly Val Leu 
305                 310                 315                 320


Arg Asn Arg Lys Ser His His Tyr Lys Lys His Tyr Pro Asn Glu Asp 
                325                 330                 335


Ala Pro Lys Ser Gly Thr Ser Cys Ser Ser Arg Cys Ser Ser Ser Arg 
            340                 345                 350


Gln Asp Ser Glu Ser Ala Arg Pro Glu Ser Glu Thr Glu Asp Val Leu 
        355                 360                 365


Trp Glu Asp Leu Leu His Cys Ala Glu Cys His Ser Ser Cys Thr Ser 
    370                 375                 380


Glu Thr Asp Val Glu Asn His Gln Ile Asn Pro Cys Val Lys Lys Glu 
385                 390                 395                 400


Tyr Arg Asp Asp Pro Phe His Gln Ser His Leu Pro Trp Leu His Ser 
                405                 410                 415


Ser His Pro Gly Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn 
            420                 425                 430


Asp Cys Lys Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile 
        435                 440                 445


Met Asn Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe 
    450                 455                 460


Gly Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg 
465                 470                 475                 480


Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala Ser 
                485                 490                 495


Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile Val Leu 
            500                 505                 510


Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu Val Trp Ile 
        515                 520                 525


Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr Lys Gln Val Gly 
    530                 535                 540


Ile Met 
545


<210>  5342
<211>  2026
<212>  DNA
<213>  Homo sapiens

<400>  5342
atcctccctg cccgcgcgca gtgactgcag gctccggcgc aaaatcctgc gggagagggg     60

gtggggcaac cctctggagg cagcgcgccc gcgggcagcc tcgttgtggc tccttgggct    120

ctgttggcgg cggcgctagc ttcggagtct cccgcgcgca cctcagccgc ctcctagcgg    180

cgcggcgctc gctcctacgc ctaaaatgac caatgtgtga tttcagtgga ataaatggcg    240

tccaaagtca cagatgctat agtctggtat caaaagaaga ttggagcata tgatcaacaa    300

atatgggaaa aatctgttga acagagagaa atcaaggggc taaggaataa accaaagaaa    360

acagcacatg tgaaaccaga cctcatagat gttgatcttg taagagggtc tgcatttgca    420

aaggcaaagc ctgaaagtcc ttggacttct ctgaccagaa agggaattgt tcgagttgta    480

tttttcccct ttttcttccg gtggtggtta caagtaacat caaaggtcat ctttttctgg    540

cttcttgtcc tttatcttct tcaagttgct gcaatagtat tattctgctc cacttctagc    600

ccacacagca tacctctgac agaggtgatt gggccgatat ggctgatgct gctcctggga    660

actgtgcatt gccagattgt ttccacaaga acacccaaac ctcctctaag tacagggggt    720

aaaagaagaa ggaaattaag aaaagcagcc catttggaag tacataggga aggagatggt    780

tctagtacca cagataacac acaagaggga gcagttcaga accacggtac aagcacctct    840

cacagcgttg gcactgtctt cagagatctc tggcatgctg ctttcttttt atcaggatca    900

aagaaagcaa agaattcaat tgataaatca actgaaactg acaatggcta tgtatccctt    960

gatgggaaga agactgttaa aagcggtgaa gatggaatac aaaaccatga acctcagtgt   1020

gaaactattc gaccagaaga gacagcctgg aacacaggaa cactgaggaa tggtcctagc   1080

aaagataccc aaaggacaat aacaaatgtc tctgatgaag tctccagtga ggaaggtcct   1140

gaaacaggat actcattacg tcgtcatgtg gacaggactt ctgaaggtgt tcttcggaat   1200

agaaagtcac accattataa gaaacattac cctaatgagg acgcccctaa atcgggtact   1260

agttgcagct ctcgctgttc aagttccaga caggattctg agagtgcaag gccagaatct   1320

gaaacagaag atgtgttatg ggaagacttg ttacattgtg cagaatgcca ttcatcttgt   1380

accagtgaga cagatgtgga aaatcatcag attaatccat gtgtgaaaaa agaatataga   1440

gatgaccctt ttcatcagag tcatttgccc tggctccata gttcccaccc aggattagaa   1500

aaaataagtg ctatagtatg ggaaggtaat gattgtaaga aagcagacat gtctgtactt   1560

gaaatcagtg gaatgataat gaacagagtg aacagccata taccaggaat aggataccag   1620

atttttggaa atgcagtctc tctcatactg ggtttaactc catttgtttt ccgactttct   1680

caagctacag acttggaaca actcacagca cattctgctt cagaacttta tgtgattgca   1740

tttggttcta atgaagatgt catagttctt tctatggtta taataagttt tgtggttcgc   1800

gtgtctcttg tgtggatttt cttttttttg ctctgtgtag cagaaagaac ttataaacag   1860

gtgggtataa tgtagacttc cgaataagaa tattttatcg ttttcataat attaaaagta   1920

ttcctgaagt actttattat ttcattatat catttttacc taattatttt ttattttgct   1980

tttatagtac ctaaccaaat aaaatcttaa caattcatat tttgtt                  2026


<210>  5343
<211>  546
<212>  PRT
<213>  Homo sapiens

<400>  5343

Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile 
1               5                   10                  15


Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu 
            20                  25                  30


Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro 
        35                  40                  45


Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala 
    50                  55                  60


Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg 
65                  70                  75                  80


Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser 
                85                  90                  95


Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Val Ala 
            100                 105                 110


Ala Ile Val Leu Phe Cys Ser Thr Ser Ser Pro His Ser Ile Pro Leu 
        115                 120                 125


Thr Glu Val Ile Gly Pro Ile Trp Leu Met Leu Leu Leu Gly Thr Val 
    130                 135                 140


His Cys Gln Ile Val Ser Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr 
145                 150                 155                 160


Gly Gly Lys Arg Arg Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val 
                165                 170                 175


His Arg Glu Gly Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly 
            180                 185                 190


Ala Val Gln Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val 
        195                 200                 205


Phe Arg Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys 
    210                 215                 220


Ala Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val 
225                 230                 235                 240


Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile Gln 
                245                 250                 255


Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr Ala Trp 
            260                 265                 270


Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr Gln Arg Thr 
        275                 280                 285


Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu Gly Pro Glu Thr 
    290                 295                 300


Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr Ser Glu Gly Val Leu 
305                 310                 315                 320


Arg Asn Arg Lys Ser His His Tyr Lys Lys His Tyr Pro Asn Glu Asp 
                325                 330                 335


Ala Pro Lys Ser Gly Thr Ser Cys Ser Ser Arg Cys Ser Ser Ser Arg 
            340                 345                 350


Gln Asp Ser Glu Ser Ala Arg Pro Glu Ser Glu Thr Glu Asp Val Leu 
        355                 360                 365


Trp Glu Asp Leu Leu His Cys Ala Glu Cys His Ser Ser Cys Thr Ser 
    370                 375                 380


Glu Thr Asp Val Glu Asn His Gln Ile Asn Pro Cys Val Lys Lys Glu 
385                 390                 395                 400


Tyr Arg Asp Asp Pro Phe His Gln Ser His Leu Pro Trp Leu His Ser 
                405                 410                 415


Ser His Pro Gly Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn 
            420                 425                 430


Asp Cys Lys Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile 
        435                 440                 445


Met Asn Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe 
    450                 455                 460


Gly Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg 
465                 470                 475                 480


Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala Ser 
                485                 490                 495


Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile Val Leu 
            500                 505                 510


Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu Val Trp Ile 
        515                 520                 525


Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr Lys Gln Val Gly 
    530                 535                 540


Ile Met 
545


<210>  5344
<211>  4668
<212>  DNA
<213>  Homo sapiens

<400>  5344
atcctccctg cccgcgcgca gtgactgcag gctccggcgc aaaatcctgc gggagagggg     60

gtggggcaac cctctggagg cagcgcgccc gcgggcagcc tcgttgtggc tccttgggct    120

ctgttggcgg cggcgctagc ttcggagtct cccgcgcgca cctcagccgc ctcctagcgg    180

cgcggcgctc gctcctacgc ctaaaatgac caatgtgtga tttcagtgga ataaatggcg    240

tccaaagtca cagatgctat agtctggtat caaaagaaga ttggagcata tgatcaacaa    300

atatgggaaa aatctgttga acagagagaa atcaaggggc taaggaataa accaaagaaa    360

acagcacatg tgaaaccaga cctcatagat gttgatcttg taagagggtc tgcatttgca    420

aaggcaaagc ctgaaagtcc ttggacttct ctgaccagaa agggaattgt tcgagttgta    480

tttttcccct ttttcttccg gtggtggtta caagtaacat caaaggtcat ctttttctgg    540

cttcttgtcc tttatcttct tcaagttgct gcaatagtat tattctgctc cacttctagc    600

ccacacagca tacctctgac agaggtgatt gggccgatat ggctgatgct gctcctggga    660

actgtgcatt gccagattgt ttccacaaga acacccaaac ctcctctaag tacagggggt    720

aaaagaagaa ggaaattaag aaaagcagcc catttggaag tacataggga aggagatggt    780

tctagtacca cagataacac acaagaggga gcagttcaga accacggtac aagcacctct    840

cacagcgttg gcactgtctt cagagatctc tggcatgctg ctttcttttt atcaggatca    900

aagaaagcaa agaattcaat tgataaatca actgaaactg acaatggcta tgtatccctt    960

gatgggaaga agactgttaa aagcggtgaa gatggaatac aaaaccatga acctcagtgt   1020

gaaactattc gaccagaaga gacagcctgg aacacaggaa cactgaggaa tggtcctagc   1080

aaagataccc aaaggacaat aacaaatgtc tctgatgaag tctccagtga ggaaggtcct   1140

gaaacaggat actcattacg tcgtcatgtg gacaggactt ctgaaggtgt tcttcggaat   1200

agaaagtcac accattataa gaaacattac cctaatgagg acgcccctaa atcgggtact   1260

agttgcagct ctcgctgttc aagttccaga caggattctg agagtgcaag gccagaatct   1320

gaaacagaag atgtgttatg ggaagacttg ttacattgtg cagaatgcca ttcatcttgt   1380

accagtgaga cagatgtgga aaatcatcag attaatccat gtgtgaaaaa agaatataga   1440

gatgaccctt ttcatcagag tcatttgccc tggctccata gttcccaccc aggattagaa   1500

aaaataagtg ctatagtatg ggaaggtaat gattgtaaga aagcagacat gtctgtactt   1560

gaaatcagtg gaatgataat gaacagagtg aacagccata taccaggaat aggataccag   1620

atttttggaa atgcagtctc tctcatactg ggtttaactc catttgtttt ccgactttct   1680

caagctacag acttggaaca actcacagca cattctgctt cagaacttta tgtgattgca   1740

tttggttcta atgaagatgt catagttctt tctatggtta taataagttt tgtggttcgc   1800

gtgtctcttg tgtggatttt cttttttttg ctctgtgtag cagaaagaac ttataaacag   1860

cgattacttt ttgcaaaact ctttggacat ttaacatctg caaggagggc tcgaaaatct   1920

gaggttcctc atttccggtt gaagaaagta cagaatataa aaatgtggct atctctccgt   1980

tcctatctta agcgtcgagg tcctcagcga tcagttgatg taatagtttc atctgctttc   2040

ttattgacta tctcagttgt atttatctgt tgtgcccaga taaacctcta cttgaaaatg   2100

gagaaaaaac ctaacaaaaa ggaggaactg acactagtga ataatgtttt aaaactggct   2160

actaaactgc taaaggagtt ggacagtcct tttagattat atgggcttac aatgaatccg   2220

ctgctttata acatcaccca ggttgttatc ctgtcagctg tttctggtgt tatcagtgac   2280

ttgcttggat ttaatttaaa gctatggaag attaagtcat gacaattcaa agaaaagaag   2340

atgtagcctc ttttccagaa taagagtact gactaagctg cctgaaagct tgtcactgat   2400

tctttgcttc aggagtctca gctagggagt tgaagtgttt acatcagact gtcttgtgca   2460

attcttatat ttattttact ggttcacttt tttttacatt tattttagtc tttatatttt   2520

tatttttaag cattgatgta cttagttgtt gaaagggtga tgaaactgat atccagatac   2580

ttgagatcct ggtaattggt cataaataat tggcaaaata acaaattgtg aaaatagaag   2640

ccattgctca gcaccgtttc tccatcaatg ccgtgaactt gccttacttg aggaaaaatt   2700

ctttaacttt ggaatattgc attgaactca gctatacaca taaaacattt tctttggtaa   2760

atcaagatcc agtcagggtt tctcttgaat tattttggaa caatgccagg atccaaactg   2820

attaagttac agtttaagca cccttcagta ttaatatata cggtattata taacaggtca   2880

acaagtgctc tttgatgata aaacttgtaa tagagcaata attgtaaatg gttaccatac   2940

tgtaagatat tttgataaaa attaactagt aatacttgta tttatttgaa acactgggct   3000

gtttgcacag ctccaactgt gcatgctcaa aatgtgcact ttttaaaatt gttactttta   3060

atgcgtatct ttatatggga tctgttatag tatactaggg catgatatgg tatccttttg   3120

agtgaggtat atactcatct cacaagtgaa gtgcctactg atattactaa agtacattat   3180

gtttactcaa gtaaataatt ttctccccat ggtacactct agtgtaggct attcatacca   3240

cactgaaatg aacaactgaa gaataaggct aagaaccaat aaaatatttc tctaattgct   3300

agttgtaaaa ctgtatccaa attttcagaa aagacagctt cagcttgcaa attctatcct   3360

ctaaacttat ctggtgcatt ctccccaccc cacccccatt atataagggc tattttagat   3420

gcttttaacc tccccaacaa ataatttgcc aagtgtccaa tgagaactta tcatgttggt   3480

gtgttaggta aatcgggcaa atatgatagt gtcttacatt gggccttgat tttaagttgt   3540

tatatttgta caatcgagta ttttagaaat tacatgaaac atgaaacagt ttttgcaatt   3600

ttttttaaac tgggcatctg gtttctaaaa atttatttga aacaatctag aattttcttg   3660

gtgcaaagtg tatcatgtgg aatatcctca tatttttacc atattttaag aactttaaga   3720

cgattaattg taaataattt atttgattgg tgcagttcta atccctaaat cataatctta   3780

aaatcaggaa tgtgtggaga acagagccat gtcatatcac tttgctctta ccattccttt   3840

tgatcagcct caattcagcc tcattgtgta gtatgttttt tctttctatg aaaaacaaca   3900

gaaagcattt cattttattt gcctatgttc aaatatgttt aataatgacc aaagtgcatt   3960

ctgagttttt tcaaggaatg taatactgga gctttaagaa catacttagt ttctcatgtg   4020

aaaacttagg ctttgtctga tgtttttcct tcctctattg tctaatgttg aggttgtttt   4080

taggaattat gttttataaa ctttttcaat ataaggtaca tgcctataca gaacttaaca   4140

ttttgcacag aatatatcaa atatattttg agaaaaaaag tacggcatga gttctgttag   4200

gaataaaaga tgaaactatt gtatctcaca aaaaatctta tttcagaatg gaaatatttt   4260

tgagaaaagt agctgagtat actggtttaa gaaaatgctt gttttagatt gaggttaact   4320

tagagttggg agttgattta ttaagtacag tatacctctc aacagtttat aaataatatg   4380

ttgaattatg tcagtgtggg cagcagtaga atactaaaag gaaaatgtca tgttaagcaa   4440

tttcagaaca ttaactgaac tattttcaaa gcagaaaaat tgacattgct gcctttaaga   4500

ataccatgaa tgtaagaaat tgaaagaaat tgtaaaatat cacataatat agaaatggca   4560

gttcaaagag aattgtggca gatgttgtgt gtgaactgtt gtttctttgc cacatgtgtt   4620

gtatttgaaa gttttacagt aagtttaaaa taaaacattc tgtgactg                4668


<210>  5345
<211>  695
<212>  PRT
<213>  Homo sapiens

<400>  5345

Met Ala Ser Lys Val Thr Asp Ala Ile Val Trp Tyr Gln Lys Lys Ile 
1               5                   10                  15


Gly Ala Tyr Asp Gln Gln Ile Trp Glu Lys Ser Val Glu Gln Arg Glu 
            20                  25                  30


Ile Lys Gly Leu Arg Asn Lys Pro Lys Lys Thr Ala His Val Lys Pro 
        35                  40                  45


Asp Leu Ile Asp Val Asp Leu Val Arg Gly Ser Ala Phe Ala Lys Ala 
    50                  55                  60


Lys Pro Glu Ser Pro Trp Thr Ser Leu Thr Arg Lys Gly Ile Val Arg 
65                  70                  75                  80


Val Val Phe Phe Pro Phe Phe Phe Arg Trp Trp Leu Gln Val Thr Ser 
                85                  90                  95


Lys Val Ile Phe Phe Trp Leu Leu Val Leu Tyr Leu Leu Gln Val Ala 
            100                 105                 110


Ala Ile Val Leu Phe Cys Ser Thr Ser Ser Pro His Ser Ile Pro Leu 
        115                 120                 125


Thr Glu Val Ile Gly Pro Ile Trp Leu Met Leu Leu Leu Gly Thr Val 
    130                 135                 140


His Cys Gln Ile Val Ser Thr Arg Thr Pro Lys Pro Pro Leu Ser Thr 
145                 150                 155                 160


Gly Gly Lys Arg Arg Arg Lys Leu Arg Lys Ala Ala His Leu Glu Val 
                165                 170                 175


His Arg Glu Gly Asp Gly Ser Ser Thr Thr Asp Asn Thr Gln Glu Gly 
            180                 185                 190


Ala Val Gln Asn His Gly Thr Ser Thr Ser His Ser Val Gly Thr Val 
        195                 200                 205


Phe Arg Asp Leu Trp His Ala Ala Phe Phe Leu Ser Gly Ser Lys Lys 
    210                 215                 220


Ala Lys Asn Ser Ile Asp Lys Ser Thr Glu Thr Asp Asn Gly Tyr Val 
225                 230                 235                 240


Ser Leu Asp Gly Lys Lys Thr Val Lys Ser Gly Glu Asp Gly Ile Gln 
                245                 250                 255


Asn His Glu Pro Gln Cys Glu Thr Ile Arg Pro Glu Glu Thr Ala Trp 
            260                 265                 270


Asn Thr Gly Thr Leu Arg Asn Gly Pro Ser Lys Asp Thr Gln Arg Thr 
        275                 280                 285


Ile Thr Asn Val Ser Asp Glu Val Ser Ser Glu Glu Gly Pro Glu Thr 
    290                 295                 300


Gly Tyr Ser Leu Arg Arg His Val Asp Arg Thr Ser Glu Gly Val Leu 
305                 310                 315                 320


Arg Asn Arg Lys Ser His His Tyr Lys Lys His Tyr Pro Asn Glu Asp 
                325                 330                 335


Ala Pro Lys Ser Gly Thr Ser Cys Ser Ser Arg Cys Ser Ser Ser Arg 
            340                 345                 350


Gln Asp Ser Glu Ser Ala Arg Pro Glu Ser Glu Thr Glu Asp Val Leu 
        355                 360                 365


Trp Glu Asp Leu Leu His Cys Ala Glu Cys His Ser Ser Cys Thr Ser 
    370                 375                 380


Glu Thr Asp Val Glu Asn His Gln Ile Asn Pro Cys Val Lys Lys Glu 
385                 390                 395                 400


Tyr Arg Asp Asp Pro Phe His Gln Ser His Leu Pro Trp Leu His Ser 
                405                 410                 415


Ser His Pro Gly Leu Glu Lys Ile Ser Ala Ile Val Trp Glu Gly Asn 
            420                 425                 430


Asp Cys Lys Lys Ala Asp Met Ser Val Leu Glu Ile Ser Gly Met Ile 
        435                 440                 445


Met Asn Arg Val Asn Ser His Ile Pro Gly Ile Gly Tyr Gln Ile Phe 
    450                 455                 460


Gly Asn Ala Val Ser Leu Ile Leu Gly Leu Thr Pro Phe Val Phe Arg 
465                 470                 475                 480


Leu Ser Gln Ala Thr Asp Leu Glu Gln Leu Thr Ala His Ser Ala Ser 
                485                 490                 495


Glu Leu Tyr Val Ile Ala Phe Gly Ser Asn Glu Asp Val Ile Val Leu 
            500                 505                 510


Ser Met Val Ile Ile Ser Phe Val Val Arg Val Ser Leu Val Trp Ile 
        515                 520                 525


Phe Phe Phe Leu Leu Cys Val Ala Glu Arg Thr Tyr Lys Gln Arg Leu 
    530                 535                 540


Leu Phe Ala Lys Leu Phe Gly His Leu Thr Ser Ala Arg Arg Ala Arg 
545                 550                 555                 560


Lys Ser Glu Val Pro His Phe Arg Leu Lys Lys Val Gln Asn Ile Lys 
                565                 570                 575


Met Trp Leu Ser Leu Arg Ser Tyr Leu Lys Arg Arg Gly Pro Gln Arg 
            580                 585                 590


Ser Val Asp Val Ile Val Ser Ser Ala Phe Leu Leu Thr Ile Ser Val 
        595                 600                 605


Val Phe Ile Cys Cys Ala Gln Ile Asn Leu Tyr Leu Lys Met Glu Lys 
    610                 615                 620


Lys Pro Asn Lys Lys Glu Glu Leu Thr Leu Val Asn Asn Val Leu Lys 
625                 630                 635                 640


Leu Ala Thr Lys Leu Leu Lys Glu Leu Asp Ser Pro Phe Arg Leu Tyr 
                645                 650                 655


Gly Leu Thr Met Asn Pro Leu Leu Tyr Asn Ile Thr Gln Val Val Ile 
            660                 665                 670


Leu Ser Ala Val Ser Gly Val Ile Ser Asp Leu Leu Gly Phe Asn Leu 
        675                 680                 685


Lys Leu Trp Lys Ile Lys Ser 
    690                 695


<210>  5346
<211>  1315
<212>  DNA
<213>  Homo sapiens

<400>  5346
aaatttacag ctgccttgca caattactct tacacctcct tcagggctac ttagaaccac     60

cataacacaa agacaacatc atggctggat ccacgacttg cgaaaaaggc taaacctcca    120

gaagagtgca aagaaaatga gcttccatat ggctgggaaa aaatcgatga tcccatttat    180

ggcacttatt atgttgacca cataaataga agaacacagt ttgaaaatcc tgtcctggaa    240

gcaaaaagga agctacagca acataacatg ccccacacag aacttggaac aaagcccctg    300

caggccccag gtttccgaga aaaaccactc ttcacccggg atgcatccca gttgaaggga    360

acattcctca gcaccaccct aaaaaagagc aacatgggct ttggatttac catcattggt    420

ggagacgagc ctgatgagtt tctgcaggtg aaaagtgtga ttccggatgg gcctgcagca    480

caggatggaa aaatggaaac aggtgatgtc attgtctata ttaatgaagt ttgtgtcctt    540

ggacacactc atgcagatgt tgtcaaactt ttccagtctg ttcctattgg tcagagtgtc    600

aacctggtgt tgtgtcgtgg ctaccctttg ccctttgatc ctgaagaccc tgctaacagc    660

atggtgccac cccttgcaat aatggagagg ccacctccag tgatggtcaa tggaagacac    720

aactatgaaa catatttgga gtacatttct cggacctcac agtcagttcc agatataaca    780

gatcggccgc ctcattctct gcactccatg ccaactgatg gtcagctaga cggcacgtat    840

ccaccgcccg tccatgatga caatgtgtct atggcttcat ctggggccac ccaagctgaa    900

cttatgacct taaccattgt gaaaggtgcc cagggcttcg gcttcactat tgccgacagt    960

cctacaggac agcgggtgaa acaaatactt gacattcagg gatgccctgg cctgtgtgaa   1020

ggcgacctca ttgttgagat caaccagcag aatgtacaga acctgagcca tacagaagta   1080

gtggatatac ttaaggactg tcccattgga agtgaaactt ctttgattat ccatcgagga   1140

ggtaagacaa acactggctc agcaataaaa tatgtgggta aaatagtagg atcatttaat   1200

aatattgtta aaatgcagat ttccttggag ttgaatgaaa ttatacttta aaaaataaag   1260

cttaaagagt gagagagaaa aacatgaatt aaaggaaact ttgtttttga attca        1315


<210>  5347
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  5347

Met Pro His Thr Glu Leu Gly Thr Lys Pro Leu Gln Ala Pro Gly Phe 
1               5                   10                  15


Arg Glu Lys Pro Leu Phe Thr Arg Asp Ala Ser Gln Leu Lys Gly Thr 
            20                  25                  30


Phe Leu Ser Thr Thr Leu Lys Lys Ser Asn Met Gly Phe Gly Phe Thr 
        35                  40                  45


Ile Ile Gly Gly Asp Glu Pro Asp Glu Phe Leu Gln Val Lys Ser Val 
    50                  55                  60


Ile Pro Asp Gly Pro Ala Ala Gln Asp Gly Lys Met Glu Thr Gly Asp 
65                  70                  75                  80


Val Ile Val Tyr Ile Asn Glu Val Cys Val Leu Gly His Thr His Ala 
                85                  90                  95


Asp Val Val Lys Leu Phe Gln Ser Val Pro Ile Gly Gln Ser Val Asn 
            100                 105                 110


Leu Val Leu Cys Arg Gly Tyr Pro Leu Pro Phe Asp Pro Glu Asp Pro 
        115                 120                 125


Ala Asn Ser Met Val Pro Pro Leu Ala Ile Met Glu Arg Pro Pro Pro 
    130                 135                 140


Val Met Val Asn Gly Arg His Asn Tyr Glu Thr Tyr Leu Glu Tyr Ile 
145                 150                 155                 160


Ser Arg Thr Ser Gln Ser Val Pro Asp Ile Thr Asp Arg Pro Pro His 
                165                 170                 175


Ser Leu His Ser Met Pro Thr Asp Gly Gln Leu Asp Gly Thr Tyr Pro 
            180                 185                 190


Pro Pro Val His Asp Asp Asn Val Ser Met Ala Ser Ser Gly Ala Thr 
        195                 200                 205


Gln Ala Glu Leu Met Thr Leu Thr Ile Val Lys Gly Ala Gln Gly Phe 
    210                 215                 220


Gly Phe Thr Ile Ala Asp Ser Pro Thr Gly Gln Arg Val Lys Gln Ile 
225                 230                 235                 240


Leu Asp Ile Gln Gly Cys Pro Gly Leu Cys Glu Gly Asp Leu Ile Val 
                245                 250                 255


Glu Ile Asn Gln Gln Asn Val Gln Asn Leu Ser His Thr Glu Val Val 
            260                 265                 270


Asp Ile Leu Lys Asp Cys Pro Ile Gly Ser Glu Thr Ser Leu Ile Ile 
        275                 280                 285


His Arg Gly Gly Lys Thr Asn Thr Gly Ser Ala Ile Lys Tyr Val Gly 
    290                 295                 300


Lys Ile Val Gly Ser Phe Asn Asn Ile Val Lys Met Gln Ile Ser Leu 
305                 310                 315                 320


Glu Leu Asn Glu Ile Ile Leu 
                325


<210>  5348
<211>  1882
<212>  DNA
<213>  Homo sapiens

<400>  5348
ggatatacaa tttcacattg gcatgtgcac acacacttat tgtgtgtata caccctgcac     60

gtccccaaca taaaccactt acagcttcag aaaggaaagg agacagaagc agcaacatct    120

caacaaccaa tttccaatac tatgaatcag atcatttcaa agcagttccc agaaacatga    180

tacccaggga gaacccaaca atgaagttat ggttgttatt tttttgagaa gggaaagact    240

actgatgaga gatgcttcca aattaaaagt ggcaaaggac tcaggatatt taaggatgag    300

attccattgc ctgatctctt tgtctttaca ttcacttatc tgcagtctga ctctctcctc    360

tcaccatgga atggaaactt agaccttggg aagacttcat aattttttct ctactgtcat    420

gtttgaataa atggaataaa aacaacttca tgctttggaa actgggagga aaataaccct    480

agaaggatct tctggagcca accctcttca aagaagacag gatagtataa ttatgaactc    540

agtctctgta gtcatgatgc tcacatccaa gcccctgcac atcctaggaa gattcatcac    600

taagccatta ctcttcacta attccatgga aaacttcgaa ctaactccta gcagacatgg    660

ccgtgtgcac catcaatcat gtcatgaagc acccaggacc tacaaggtgg ctgctgaaga    720

cagcagaaag acagaacctg gtgctcagtg gccaaggcca tcttgtgggc cacccggcag    780

ccatcttggc caagtgggtt ctgctgggaa ggaaactggt ggttgagcac cacgagggca    840

tcaacatttc tggcaatttc tggagaaaca aattaaagta tctggccttc ctctgcaagc    900

agatgagcac caacccttcc caaggcccac ccgccccgcc attcctgggc ccccagcgca    960

tcttttggtg gccttgcaga accaagtggg gccaggctgc cctggaccac cttatggtgt   1020

tttatgggat ctcactgccc tatgacaagg tggttcctgc tgccctttag gttgtacgac   1080

tgaagcctac aagaaagttt gcctccttgg ggtgcctggc tcacgaggtt ggctggaaat   1140

accaggtagt gacagccacc atgggggaga agaggaagga gaaggccaag atgcactaca   1200

ggaagaaaaa gcagctcatg cggctgcaga aacaggccac aaagaacgtg gagaagacaa   1260

atgacaaata cacagaggtc ctaagaccga gggactccct gtttgagacc agaaaagact   1320

gtttattcct catgcttggc ctggcctacc cttctgccat tgcgaccttg ggatatgggg   1380

gagcctaccc ttcctgcatc accgccctgg gatgtggggg atccaagggc agcaatatag   1440

gtgccatggg cagcctggga cttaagctgg gggcaaggga agggccttag tcactgcctt   1500

tctataaggt tattttaaac agctctaaga tttgtacagg aataatttgt ctatgaccta   1560

cttgttcagg acagagtttt agaaaaccaa tagagcaacc agttactttg gttttaatat   1620

tggcaaaagg gacctggaac attaattgga gggagccccg cctcgtgaaa ggggcatctc   1680

tttttaactc ccaccttctc gtgctatact ctgtggctgt tataatatga aaaagtgctt   1740

agggacagca tgatcttact gttattcaaa ggatattata gagaagctta gactaggaag   1800

atgtgtgacc aagaggtggc aggggtcgcc cttgctcctt ccctgtattt tgtgaccaga   1860

atgaaataaa ttactttcaa ag                                            1882


<210>  5349
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  5349

Met Ala Val Cys Thr Ile Asn His Val Met Lys His Pro Gly Pro Thr 
1               5                   10                  15


Arg Trp Leu Leu Lys Thr Ala Glu Arg Gln Asn Leu Val Leu Ser Gly 
            20                  25                  30


Gln Gly His Leu Val Gly His Pro Ala Ala Ile Leu Ala Lys Trp Val 
        35                  40                  45


Leu Leu Gly Arg Lys Leu Val Val Glu His His Glu Gly Ile Asn Ile 
    50                  55                  60


Ser Gly Asn Phe Trp Arg Asn Lys Leu Lys Tyr Leu Ala Phe Leu Cys 
65                  70                  75                  80


Lys Gln Met Ser Thr Asn Pro Ser Gln Gly Pro Pro Ala Pro Pro Phe 
                85                  90                  95


Leu Gly Pro Gln Arg Ile Phe Trp Trp Pro Cys Arg Thr Lys Trp Gly 
            100                 105                 110


Gln Ala Ala Leu Asp His Leu Met Val Phe Tyr Gly Ile Ser Leu Pro 
        115                 120                 125


Tyr Asp Lys Val Val Pro Ala Ala Leu 
    130                 135


<210>  5350
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  5350
aacataaacc acttacagct tcagaaagga aaggagacag aagcagcaac atctcaacaa     60

ccaatttcca atactatgaa tcagatcatt tcaaagcagt tcccagaaac atgaagggaa    120

agactactga tgagagatgc ttccaaatta aaagtggcaa aggactcagg atatttaagg    180

atgagattcc attgcctgat ctctttgtct ttacattcac ttatctgcag tctgactctc    240

tcctctcacc atggaatgga aacttagagt aagttcgtat gtggcagtgc tttgaaattc    300

cagatgcacc agagagcttc aaaaacaaac agaaaacaga agactcaggg ctaccctaaa    360

tcaactgatt cataatttca gaatgagatc cacaggcatt ggcatttttt agatgaaaga    420

aagcttccca ggtgtctcta gtgtgcagct acggctgtga tcccctgagt tagaagctga    480

gaatgtgtga agaggtgttg cataaggagt atcttgcctg ataagattta tgcagaagcc    540

tct                                                                  543


<210>  5351
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  5351

Met Lys Gly Lys Thr Thr Asp Glu Arg Cys Phe Gln Ile Lys Ser Gly 
1               5                   10                  15


Lys Gly Leu Arg Ile Phe Lys Asp Glu Ile Pro Leu Pro Asp Leu Phe 
            20                  25                  30


Val Phe Thr Phe Thr Tyr Leu Gln Ser Asp Ser Leu Leu Ser Pro Trp 
        35                  40                  45


Asn Gly Asn Leu Glu 
    50


<210>  5352
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  5352
agaaaggaaa ggagacagaa gcagcaacat ctcaacaacc aatttccaat actatgaatc     60

agatcatttc aaagcagttc ccagaaacat gatacccagg gagaacccaa caatgaagtt    120

atggttgtta tttttttgag aagggaaaga ctactgatga gagatgcttc caaattaaaa    180

gtggcaaagg actcaggata tttaaggatg agattccatt gcctgatctc tttgtcttta    240

cattcactta tctgcagtct gactctctcc tctcaccatg gaatggaaac ttagagtaag    300

ttcgtatgtg gcagtgcttt gaaattccag atgcaccaga gagcttcaaa aacaaacaga    360

aaacagaaga ctcagggcta ccctaaatca actgattcat aatttcagaa tgagatccac    420

aggcattggc attttttaga tgaaagaaag cttcccaggt gtctctagtg tgcagctacg    480

gctgtgatcc cctgagttag aagctgagaa tgtgtgaaga ggtgttgcat aaggagtatc    540

ttg                                                                  543


<210>  5353
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5353

Met Val Val Ile Phe Leu Arg Arg Glu Arg Leu Leu Met Arg Asp Ala 
1               5                   10                  15


Ser Lys Leu Lys Val Ala Lys Asp Ser Gly Tyr Leu Arg Met Arg Phe 
            20                  25                  30


His Cys Leu Ile Ser Leu Ser Leu His Ser Leu Ile Cys Ser Leu Thr 
        35                  40                  45


Leu Ser Ser His His Gly Met Glu Thr 
    50                  55


<210>  5354
<211>  5618
<212>  DNA
<213>  Homo sapiens

<400>  5354
actgattagt gctttcaagc ctgcctgcct tagttcatgt agctcctcct ctggtactgg     60

gataaacact tgtattacca ttttaaaggc tatcattact ctttacctgt gaagagtaga    120

acatgaagaa atctacttta ttcagatatt ctccagattc ctaaagatta gagatcattt    180

ctcattctcc taggagtact cacttcagga agcaaccaga taaaagagag gtgcaacgga    240

agccagaaca ttcctcctgg aaattcaacc tgtttcgcag tttctcgagg aatcagcatt    300

cagtcaatcc gggccgggag cagtcatctg tggtgaggct gattggctgg gcaggaacag    360

cgccggggcg tgggctgagc acagccgctt cgctctcttt gccacaggaa gcctgagctc    420

attcgagtag cggctcttcc aagctcaaag aagcagaggc cgctgttcgt ttcctttagg    480

tctttccact aaagtcggag tatcttcttc caaaatttca cgtcttggtg gccgttccaa    540

ggagcgcgag gtcggaatgg atcttgaagg ggaccgcaat ggaggagcaa agaagaagaa    600

cttttttaaa ctgaacaata aaagtgaaaa agataagaag gaaaagaaac caactgtcag    660

tgtattttca atgtttcgct attcaaattg gcttgacaag ttgtatatgg tggtgggaac    720

tttggctgcc atcatccatg gggctggact tcctctcatg atgctggtgt ttggagaaat    780

gacagatatc tttgcaaatg caggaaattt agaagatctg atgtcaaaca tcactaatag    840

aagtgatatc aatgatacag ggttcttcat gaatctggag gaagacatga ccaggtatgc    900

ctattattac agtggaattg gtgctggggt gctggttgct gcttacattc aggtttcatt    960

ttggtgcctg gcagctggaa gacaaataca caaaattaga aaacagtttt ttcatgctat   1020

aatgcgacag gagataggct ggtttgatgt gcacgatgtt ggggagctta acacccgact   1080

tacagatgat gtctccaaga ttaatgaagg aattggtgac aaaattggaa tgttctttca   1140

gtcaatggca acatttttca ctgggtttat agtaggattt acacgtggtt ggaagctaac   1200

ccttgtgatt ttggccatca gtcctgttct tggactgtca gctgctgtct gggcaaagat   1260

actatcttca tttactgata aagaactctt agcgtatgca aaagctggag cagtagctga   1320

agaggtcttg gcagcaatta gaactgtgat tgcatttgga ggacaaaaga aagaacttga   1380

aaggtacaac aaaaatttag aagaagctaa aagaattggg ataaagaaag ctattacagc   1440

caatatttct ataggtgctg ctttcctgct gatctatgca tcttatgctc tggccttctg   1500

gtatgggacc accttggtcc tctcagggga atattctatt ggacaagtac tcactgtatt   1560

cttttctgta ttaattgggg cttttagtgt tggacaggca tctccaagca ttgaagcatt   1620

tgcaaatgca agaggagcag cttatgaaat cttcaagata attgataata agccaagtat   1680

tgacagctat tcgaagagtg ggcacaaacc agataatatt aagggaaatt tggaattcag   1740

aaatgttcac ttcagttacc catctcgaaa agaagttaag atcttgaagg gtctgaacct   1800

gaaggtgcag agtgggcaga cggtggccct ggttggaaac agtggctgtg ggaagagcac   1860

aacagtccag ctgatgcaga ggctctatga ccccacagag gggatggtca gtgttgatgg   1920

acaggatatt aggaccataa atgtaaggtt tctacgggaa atcattggtg tggtgagtca   1980

ggaacctgta ttgtttgcca ccacgatagc tgaaaacatt cgctatggcc gtgaaaatgt   2040

caccatggat gagattgaga aagctgtcaa ggaagccaat gcctatgact ttatcatgaa   2100

actgcctcat aaatttgaca ccctggttgg agagagaggg gcccagttga gtggtgggca   2160

gaagcagagg atcgccattg cacgtgccct ggttcgcaac cccaagatcc tcctgctgga   2220

tgaggccacg tcagccttgg acacagaaag cgaagcagtg gttcaggtgg ctctggataa   2280

ggccagaaaa ggtcggacca ccattgtgat agctcatcgt ttgtctacag ttcgtaatgc   2340

tgacgtcatc gctggtttcg atgatggagt cattgtggag aaaggaaatc atgatgaact   2400

catgaaagag aaaggcattt acttcaaact tgtcacaatg cagacagcag gaaatgaagt   2460

tgaattagaa aatgcagctg atgaatccaa aagtgaaatt gatgccttgg aaatgtcttc   2520

aaatgattca agatccagtc taataagaaa aagatcaact cgtaggagtg tccgtggatc   2580

acaagcccaa gacagaaagc ttagtaccaa agaggctctg gatgaaagta tacctccagt   2640

ttccttttgg aggattatga agctaaattt aactgaatgg ccttattttg ttgttggtgt   2700

attttgtgcc attataaatg gaggcctgca accagcattt gcaataatat tttcaaagat   2760

tataggggtt tttacaagaa ttgatgatcc tgaaacaaaa cgacagaata gtaacttgtt   2820

ttcactattg tttctagccc ttggaattat ttcttttatt acatttttcc ttcagggttt   2880

cacatttggc aaagctggag agatcctcac caagcggctc cgatacatgg ttttccgatc   2940

catgctcaga caggatgtga gttggtttga tgaccctaaa aacaccactg gagcattgac   3000

taccaggctc gccaatgatg ctgctcaagt taaaggggct ataggttcca ggcttgctgt   3060

aattacccag aatatagcaa atcttgggac aggaataatt atatccttca tctatggttg   3120

gcaactaaca ctgttactct tagcaattgt acccatcatt gcaatagcag gagttgttga   3180

aatgaaaatg ttgtctggac aagcactgaa agataagaaa gaactagaag gttctgggaa   3240

gatcgctact gaagcaatag aaaacttccg aaccgttgtt tctttgactc aggagcagaa   3300

gtttgaacat atgtatgctc agagtttgca ggtaccatac agaaactctt tgaggaaagc   3360

acacatcttt ggaattacat tttccttcac ccaggcaatg atgtattttt cctatgctgg   3420

atgtttccgg tttggagcct acttggtggc acataaactc atgagctttg aggatgttct   3480

gttagtattt tcagctgttg tctttggtgc catggccgtg gggcaagtca gttcatttgc   3540

tcctgactat gccaaagcca aaatatcagc agcccacatc atcatgatca ttgaaaaaac   3600

ccctttgatt gacagctaca gcacggaagg cctaatgccg aacacattgg aaggaaatgt   3660

cacatttggt gaagttgtat tcaactatcc cacccgaccg gacatcccag tgcttcaggg   3720

actgagcctg gaggtgaaga agggccagac gctggctctg gtgggcagca gtggctgtgg   3780

gaagagcaca gtggtccagc tcctggagcg gttctacgac cccttggcag ggaaagtgct   3840

gcttgatggc aaagaaataa agcgactgaa tgttcagtgg ctccgagcac acctgggcat   3900

cgtgtcccag gagcccatcc tgtttgactg cagcattgct gagaacattg cctatggaga   3960

caacagccgg gtggtgtcac aggaagagat tgtgagggca gcaaaggagg ccaacataca   4020

tgccttcatc gagtcactgc ctaataaata tagcactaaa gtaggagaca aaggaactca   4080

gctctctggt ggccagaaac aacgcattgc catagctcgt gcccttgtta gacagcctca   4140

tattttgctt ttggatgaag ccacgtcagc tctggataca gaaagtgaaa aggttgtcca   4200

agaagccctg gacaaagcca gagaaggccg cacctgcatt gtgattgctc accgcctgtc   4260

caccatccag aatgcagact taatagtggt gtttcagaat ggcagagtca aggagcatgg   4320

cacgcatcag cagctgctgg cacagaaagg catctatttt tcaatggtca gtgtccaggc   4380

tggaacaaag cgccagtgaa ctctgactgt atgagatgtt aaatactttt taatatttgt   4440

ttagatatga catttattca aagttaaaag caaacactta cagaattatg aagaggtatc   4500

tgtttaacat ttcctcagtc aagttcagag tcttcagaga cttcgtaatt aaaggaacag   4560

agtgagagac atcatcaagt ggagagaaat catagtttaa actgcattat aaattttata   4620

acagaattaa agtagatttt aaaagataaa atgtgtaatt ttgtttatat tttcccattt   4680

ggactgtaac tgactgcctt gctaaaagat tatagaagta gcaaaaagta ttgaaatgtt   4740

tgcataaagt gtctataata aaactaaact ttcatgtgac tggagtcatc ttgtccaaac   4800

tgcctgtgaa tatatcttct ctcaattgga atattgtaga taacttctgc tttaaaaaag   4860

ttttctttaa atatacctac tcatttttgt gggaatggtt aagcagttta aataattcct   4920

gttgtatatg tctattcaca ttgggtctta cagaaccatc tggcttcatt cttcttggac   4980

ttgatcctgc tgattcttgc atttccacat taaggtggct ctcaaaccca aaacacagat   5040

cgatataaga ttttaggagg tggggtgagg cacaattatg aagtgcatat tattcagatg   5100

tatagtaaat actttgcatt gcttttataa agggttcttt aaggattttt taagattttt   5160

acacttccaa agtacattta ctttttgtct tgataatgaa tcacttttgc cagtaattgg   5220

cctcttccaa aagtgatcct tctgacttac agatgtttaa aatgtgccat gagtttaact   5280

acatcttgat acaaacatga taaaaaaaga aaaaaatata ttccaaaggt tgggactctg   5340

gacgacaaat ttttttaaat tagccaaaaa gcattattaa cattataaac tatatttact   5400

ataaacaatt gctatcttaa ataagcaact tctaaaaata aaaaaaagaa gccatcacct   5460

ccaggaaaaa aaaataggaa aggatataat caggtaattc tcaaagaaga aatgcatgag   5520

aaaaatgtat acagtttcaa caatcaaata aatgcaaatt aaaacaaaat atcatttttt   5580

tgccttgtaa tttaatgatg aataaaaaaa tctaatgt                           5618


<210>  5355
<211>  1280
<212>  PRT
<213>  Homo sapiens

<400>  5355

Met Asp Leu Glu Gly Asp Arg Asn Gly Gly Ala Lys Lys Lys Asn Phe 
1               5                   10                  15


Phe Lys Leu Asn Asn Lys Ser Glu Lys Asp Lys Lys Glu Lys Lys Pro 
            20                  25                  30


Thr Val Ser Val Phe Ser Met Phe Arg Tyr Ser Asn Trp Leu Asp Lys 
        35                  40                  45


Leu Tyr Met Val Val Gly Thr Leu Ala Ala Ile Ile His Gly Ala Gly 
    50                  55                  60


Leu Pro Leu Met Met Leu Val Phe Gly Glu Met Thr Asp Ile Phe Ala 
65                  70                  75                  80


Asn Ala Gly Asn Leu Glu Asp Leu Met Ser Asn Ile Thr Asn Arg Ser 
                85                  90                  95


Asp Ile Asn Asp Thr Gly Phe Phe Met Asn Leu Glu Glu Asp Met Thr 
            100                 105                 110


Arg Tyr Ala Tyr Tyr Tyr Ser Gly Ile Gly Ala Gly Val Leu Val Ala 
        115                 120                 125


Ala Tyr Ile Gln Val Ser Phe Trp Cys Leu Ala Ala Gly Arg Gln Ile 
    130                 135                 140


His Lys Ile Arg Lys Gln Phe Phe His Ala Ile Met Arg Gln Glu Ile 
145                 150                 155                 160


Gly Trp Phe Asp Val His Asp Val Gly Glu Leu Asn Thr Arg Leu Thr 
                165                 170                 175


Asp Asp Val Ser Lys Ile Asn Glu Gly Ile Gly Asp Lys Ile Gly Met 
            180                 185                 190


Phe Phe Gln Ser Met Ala Thr Phe Phe Thr Gly Phe Ile Val Gly Phe 
        195                 200                 205


Thr Arg Gly Trp Lys Leu Thr Leu Val Ile Leu Ala Ile Ser Pro Val 
    210                 215                 220


Leu Gly Leu Ser Ala Ala Val Trp Ala Lys Ile Leu Ser Ser Phe Thr 
225                 230                 235                 240


Asp Lys Glu Leu Leu Ala Tyr Ala Lys Ala Gly Ala Val Ala Glu Glu 
                245                 250                 255


Val Leu Ala Ala Ile Arg Thr Val Ile Ala Phe Gly Gly Gln Lys Lys 
            260                 265                 270


Glu Leu Glu Arg Tyr Asn Lys Asn Leu Glu Glu Ala Lys Arg Ile Gly 
        275                 280                 285


Ile Lys Lys Ala Ile Thr Ala Asn Ile Ser Ile Gly Ala Ala Phe Leu 
    290                 295                 300


Leu Ile Tyr Ala Ser Tyr Ala Leu Ala Phe Trp Tyr Gly Thr Thr Leu 
305                 310                 315                 320


Val Leu Ser Gly Glu Tyr Ser Ile Gly Gln Val Leu Thr Val Phe Phe 
                325                 330                 335


Ser Val Leu Ile Gly Ala Phe Ser Val Gly Gln Ala Ser Pro Ser Ile 
            340                 345                 350


Glu Ala Phe Ala Asn Ala Arg Gly Ala Ala Tyr Glu Ile Phe Lys Ile 
        355                 360                 365


Ile Asp Asn Lys Pro Ser Ile Asp Ser Tyr Ser Lys Ser Gly His Lys 
    370                 375                 380


Pro Asp Asn Ile Lys Gly Asn Leu Glu Phe Arg Asn Val His Phe Ser 
385                 390                 395                 400


Tyr Pro Ser Arg Lys Glu Val Lys Ile Leu Lys Gly Leu Asn Leu Lys 
                405                 410                 415


Val Gln Ser Gly Gln Thr Val Ala Leu Val Gly Asn Ser Gly Cys Gly 
            420                 425                 430


Lys Ser Thr Thr Val Gln Leu Met Gln Arg Leu Tyr Asp Pro Thr Glu 
        435                 440                 445


Gly Met Val Ser Val Asp Gly Gln Asp Ile Arg Thr Ile Asn Val Arg 
    450                 455                 460


Phe Leu Arg Glu Ile Ile Gly Val Val Ser Gln Glu Pro Val Leu Phe 
465                 470                 475                 480


Ala Thr Thr Ile Ala Glu Asn Ile Arg Tyr Gly Arg Glu Asn Val Thr 
                485                 490                 495


Met Asp Glu Ile Glu Lys Ala Val Lys Glu Ala Asn Ala Tyr Asp Phe 
            500                 505                 510


Ile Met Lys Leu Pro His Lys Phe Asp Thr Leu Val Gly Glu Arg Gly 
        515                 520                 525


Ala Gln Leu Ser Gly Gly Gln Lys Gln Arg Ile Ala Ile Ala Arg Ala 
    530                 535                 540


Leu Val Arg Asn Pro Lys Ile Leu Leu Leu Asp Glu Ala Thr Ser Ala 
545                 550                 555                 560


Leu Asp Thr Glu Ser Glu Ala Val Val Gln Val Ala Leu Asp Lys Ala 
                565                 570                 575


Arg Lys Gly Arg Thr Thr Ile Val Ile Ala His Arg Leu Ser Thr Val 
            580                 585                 590


Arg Asn Ala Asp Val Ile Ala Gly Phe Asp Asp Gly Val Ile Val Glu 
        595                 600                 605


Lys Gly Asn His Asp Glu Leu Met Lys Glu Lys Gly Ile Tyr Phe Lys 
    610                 615                 620


Leu Val Thr Met Gln Thr Ala Gly Asn Glu Val Glu Leu Glu Asn Ala 
625                 630                 635                 640


Ala Asp Glu Ser Lys Ser Glu Ile Asp Ala Leu Glu Met Ser Ser Asn 
                645                 650                 655


Asp Ser Arg Ser Ser Leu Ile Arg Lys Arg Ser Thr Arg Arg Ser Val 
            660                 665                 670


Arg Gly Ser Gln Ala Gln Asp Arg Lys Leu Ser Thr Lys Glu Ala Leu 
        675                 680                 685


Asp Glu Ser Ile Pro Pro Val Ser Phe Trp Arg Ile Met Lys Leu Asn 
    690                 695                 700


Leu Thr Glu Trp Pro Tyr Phe Val Val Gly Val Phe Cys Ala Ile Ile 
705                 710                 715                 720


Asn Gly Gly Leu Gln Pro Ala Phe Ala Ile Ile Phe Ser Lys Ile Ile 
                725                 730                 735


Gly Val Phe Thr Arg Ile Asp Asp Pro Glu Thr Lys Arg Gln Asn Ser 
            740                 745                 750


Asn Leu Phe Ser Leu Leu Phe Leu Ala Leu Gly Ile Ile Ser Phe Ile 
        755                 760                 765


Thr Phe Phe Leu Gln Gly Phe Thr Phe Gly Lys Ala Gly Glu Ile Leu 
    770                 775                 780


Thr Lys Arg Leu Arg Tyr Met Val Phe Arg Ser Met Leu Arg Gln Asp 
785                 790                 795                 800


Val Ser Trp Phe Asp Asp Pro Lys Asn Thr Thr Gly Ala Leu Thr Thr 
                805                 810                 815


Arg Leu Ala Asn Asp Ala Ala Gln Val Lys Gly Ala Ile Gly Ser Arg 
            820                 825                 830


Leu Ala Val Ile Thr Gln Asn Ile Ala Asn Leu Gly Thr Gly Ile Ile 
        835                 840                 845


Ile Ser Phe Ile Tyr Gly Trp Gln Leu Thr Leu Leu Leu Leu Ala Ile 
    850                 855                 860


Val Pro Ile Ile Ala Ile Ala Gly Val Val Glu Met Lys Met Leu Ser 
865                 870                 875                 880


Gly Gln Ala Leu Lys Asp Lys Lys Glu Leu Glu Gly Ser Gly Lys Ile 
                885                 890                 895


Ala Thr Glu Ala Ile Glu Asn Phe Arg Thr Val Val Ser Leu Thr Gln 
            900                 905                 910


Glu Gln Lys Phe Glu His Met Tyr Ala Gln Ser Leu Gln Val Pro Tyr 
        915                 920                 925


Arg Asn Ser Leu Arg Lys Ala His Ile Phe Gly Ile Thr Phe Ser Phe 
    930                 935                 940


Thr Gln Ala Met Met Tyr Phe Ser Tyr Ala Gly Cys Phe Arg Phe Gly 
945                 950                 955                 960


Ala Tyr Leu Val Ala His Lys Leu Met Ser Phe Glu Asp Val Leu Leu 
                965                 970                 975


Val Phe Ser Ala Val Val Phe Gly Ala Met Ala Val Gly Gln Val Ser 
            980                 985                 990


Ser Phe Ala Pro Asp Tyr Ala Lys Ala Lys Ile Ser Ala Ala His Ile 
        995                 1000                1005


Ile Met Ile Ile Glu Lys Thr Pro Leu Ile Asp Ser Tyr Ser Thr Glu 
    1010                1015                1020


Gly Leu Met Pro Asn Thr Leu Glu Gly Asn Val Thr Phe Gly Glu Val 
1025                1030                1035                1040


Val Phe Asn Tyr Pro Thr Arg Pro Asp Ile Pro Val Leu Gln Gly Leu 
                1045                1050                1055


Ser Leu Glu Val Lys Lys Gly Gln Thr Leu Ala Leu Val Gly Ser Ser 
            1060                1065                1070


Gly Cys Gly Lys Ser Thr Val Val Gln Leu Leu Glu Arg Phe Tyr Asp 
        1075                1080                1085


Pro Leu Ala Gly Lys Val Leu Leu Asp Gly Lys Glu Ile Lys Arg Leu 
    1090                1095                1100


Asn Val Gln Trp Leu Arg Ala His Leu Gly Ile Val Ser Gln Glu Pro 
1105                1110                1115                1120


Ile Leu Phe Asp Cys Ser Ile Ala Glu Asn Ile Ala Tyr Gly Asp Asn 
                1125                1130                1135


Ser Arg Val Val Ser Gln Glu Glu Ile Val Arg Ala Ala Lys Glu Ala 
            1140                1145                1150


Asn Ile His Ala Phe Ile Glu Ser Leu Pro Asn Lys Tyr Ser Thr Lys 
        1155                1160                1165


Val Gly Asp Lys Gly Thr Gln Leu Ser Gly Gly Gln Lys Gln Arg Ile 
    1170                1175                1180


Ala Ile Ala Arg Ala Leu Val Arg Gln Pro His Ile Leu Leu Leu Asp 
1185                1190                1195                1200


Glu Ala Thr Ser Ala Leu Asp Thr Glu Ser Glu Lys Val Val Gln Glu 
                1205                1210                1215


Ala Leu Asp Lys Ala Arg Glu Gly Arg Thr Cys Ile Val Ile Ala His 
            1220                1225                1230


Arg Leu Ser Thr Ile Gln Asn Ala Asp Leu Ile Val Val Phe Gln Asn 
        1235                1240                1245


Gly Arg Val Lys Glu His Gly Thr His Gln Gln Leu Leu Ala Gln Lys 
    1250                1255                1260


Gly Ile Tyr Phe Ser Met Val Ser Val Gln Ala Gly Thr Lys Arg Gln 
1265                1270                1275                1280


<210>  5356
<211>  2259
<212>  DNA
<213>  Homo sapiens

<400>  5356
gctggggcac gagtggctgc ggagtgtggg tggttgggcg tgaggggccg acgggctcgc     60

gcgcgcgccg tctgctgagg tccctcggga aggaggagag cgcctgacgc cgacccgcag    120

gcgcagcccg gcagtcggcg gcgcgccgag ggcggaggtg gtgcgtgcgt gcgtgtgtgt    180

gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtggagctcg ggtgccaagg gcgagccgtc    240

agtccccggg tgcgagtccc tgctgtcttc cacacccttc ctccctccag gctcctttcc    300

tacatccttc ccgcgccccc acggttgcgg accgagcgag aaccccctta agcaggtgtg    360

gggggcgtgc ggggtggcac gagacaaaag gggcacgggg gtaagcccgc catggcctcc    420

cggagcctgg ggggcctgag cgggatccgc ggcggtggcg gcggaggcgg caagaaaagc    480

ctgagcgccc gcaatgctgc ggtggagagg aggaacctga tcaccgtgtg caggttttct    540

gtgaagaccc tgattgatcg gtcttgcttt gagacaattg atgattcttc tcctgaattt    600

aacaattttg cagctatttt ggaacagatt ttaagccacc ggctaaaaga gatttcccaa    660

agttgcagat ggctggctca tctccaaata cctcttcaag gtcaagtaac ctggtttggt    720

tatgaaagtc ctcgtagctt ctgggactat atcagagtgg cttgccggaa agtttcacag    780

aattgtatct gcagcattga aaatatggaa aatgtcagtt cttctagagc taagggtaga    840

gcctggatca gagtagcact catggaaaaa catttatctg aatacatctc tacagctctg    900

agagacttca aaacaaccag gagattttat gaagatggag caattgtctt gggtgaagaa    960

gcaaatatgc ttgctggcat gcttctagga ctcaatgcta ttgatttcag tttctgccta   1020

aagggagagg ggctggatgg cagttttcct gctgtaatag actatacacc atatttgaag   1080

tatatccaaa gttctgatag tatcagcagt gatgaggagg agctaaggac tttgggaagc   1140

agtggtagcg aaagcagtac tccagagaat gtcggacctc ctttcctcat ggatgagaac   1200

agttggttca acaagtgtaa gagagttaaa caaaagtatc agcttaccct ggaacagaag   1260

ggttaccttg aagaactctt acgacttcga gagaaccaac tatctgaatc tgtctcccag   1320

aataaaatac tacttcaaag gattgaagat tccgatctgg ctcataaact ggagaaggaa   1380

caattagaat atataattgt ggagcttcaa gatcagctga ctgtgctaaa gaataatgat   1440

ttaagatcga gacaagagtt aactgcccat ctcaccaacc agtggccttc tccaggagct   1500

ctggatgtca atgctgttgc cttggatacg ttgctttacc gaaaacacaa taaacagtgg   1560

tatgagaaaa gttatcaaag tcttgaccag ttatcagcag aagttagcct ttctcagact   1620

tcactagatc caggccagtc acaagaagga gatggaaaac aagacacatt aaatgtaatg   1680

agtgaaggta aggaagatac tccctcatta cttggcctct gtggatctct aacgtcagtg   1740

gcaagttaca agtctctaac aagcttaaaa tctaatgact accttgcaag tcctacaaca   1800

gagatgacaa gtccaggcct aactccatcc tgaaaatttt tgtgtaaaag ccaaaacttt   1860

ttatgttgta aatgtttaat ttacatgttt gactgctggg aagacctttg aaattttata   1920

ttgttctggt acatgtctga aattctattg cttggagaga atcccctcca gataagagat   1980

tttgagtgaa aaacataatg atcctgccat ttttcatttt taaaattctt acatttgtca   2040

ttgagaaagt tcaaaatgga ataggcttta aaaaaaaaaa aactttcaaa gatccgccaa   2100

atcattcata gcaaattgta catattgttc agctgatttt tatatattta aatacacctt   2160

agtggccaga gactgacttc aaggttttat tccagagact ccagagactt aagctaagta   2220

ttttttcatt ctttcagatt ttcaaaaaaa aaaaaaaaa                          2259


<210>  5357
<211>  473
<212>  PRT
<213>  Homo sapiens

<400>  5357

Met Ala Ser Arg Ser Leu Gly Gly Leu Ser Gly Ile Arg Gly Gly Gly 
1               5                   10                  15


Gly Gly Gly Gly Lys Lys Ser Leu Ser Ala Arg Asn Ala Ala Val Glu 
            20                  25                  30


Arg Arg Asn Leu Ile Thr Val Cys Arg Phe Ser Val Lys Thr Leu Ile 
        35                  40                  45


Asp Arg Ser Cys Phe Glu Thr Ile Asp Asp Ser Ser Pro Glu Phe Asn 
    50                  55                  60


Asn Phe Ala Ala Ile Leu Glu Gln Ile Leu Ser His Arg Leu Lys Glu 
65                  70                  75                  80


Ile Ser Gln Ser Cys Arg Trp Leu Ala His Leu Gln Ile Pro Leu Gln 
                85                  90                  95


Gly Gln Val Thr Trp Phe Gly Tyr Glu Ser Pro Arg Ser Phe Trp Asp 
            100                 105                 110


Tyr Ile Arg Val Ala Cys Arg Lys Val Ser Gln Asn Cys Ile Cys Ser 
        115                 120                 125


Ile Glu Asn Met Glu Asn Val Ser Ser Ser Arg Ala Lys Gly Arg Ala 
    130                 135                 140


Trp Ile Arg Val Ala Leu Met Glu Lys His Leu Ser Glu Tyr Ile Ser 
145                 150                 155                 160


Thr Ala Leu Arg Asp Phe Lys Thr Thr Arg Arg Phe Tyr Glu Asp Gly 
                165                 170                 175


Ala Ile Val Leu Gly Glu Glu Ala Asn Met Leu Ala Gly Met Leu Leu 
            180                 185                 190


Gly Leu Asn Ala Ile Asp Phe Ser Phe Cys Leu Lys Gly Glu Gly Leu 
        195                 200                 205


Asp Gly Ser Phe Pro Ala Val Ile Asp Tyr Thr Pro Tyr Leu Lys Tyr 
    210                 215                 220


Ile Gln Ser Ser Asp Ser Ile Ser Ser Asp Glu Glu Glu Leu Arg Thr 
225                 230                 235                 240


Leu Gly Ser Ser Gly Ser Glu Ser Ser Thr Pro Glu Asn Val Gly Pro 
                245                 250                 255


Pro Phe Leu Met Asp Glu Asn Ser Trp Phe Asn Lys Cys Lys Arg Val 
            260                 265                 270


Lys Gln Lys Tyr Gln Leu Thr Leu Glu Gln Lys Gly Tyr Leu Glu Glu 
        275                 280                 285


Leu Leu Arg Leu Arg Glu Asn Gln Leu Ser Glu Ser Val Ser Gln Asn 
    290                 295                 300


Lys Ile Leu Leu Gln Arg Ile Glu Asp Ser Asp Leu Ala His Lys Leu 
305                 310                 315                 320


Glu Lys Glu Gln Leu Glu Tyr Ile Ile Val Glu Leu Gln Asp Gln Leu 
                325                 330                 335


Thr Val Leu Lys Asn Asn Asp Leu Arg Ser Arg Gln Glu Leu Thr Ala 
            340                 345                 350


His Leu Thr Asn Gln Trp Pro Ser Pro Gly Ala Leu Asp Val Asn Ala 
        355                 360                 365


Val Ala Leu Asp Thr Leu Leu Tyr Arg Lys His Asn Lys Gln Trp Tyr 
    370                 375                 380


Glu Lys Ser Tyr Gln Ser Leu Asp Gln Leu Ser Ala Glu Val Ser Leu 
385                 390                 395                 400


Ser Gln Thr Ser Leu Asp Pro Gly Gln Ser Gln Glu Gly Asp Gly Lys 
                405                 410                 415


Gln Asp Thr Leu Asn Val Met Ser Glu Gly Lys Glu Asp Thr Pro Ser 
            420                 425                 430


Leu Leu Gly Leu Cys Gly Ser Leu Thr Ser Val Ala Ser Tyr Lys Ser 
        435                 440                 445


Leu Thr Ser Leu Lys Ser Asn Asp Tyr Leu Ala Ser Pro Thr Thr Glu 
    450                 455                 460


Met Thr Ser Pro Gly Leu Thr Pro Ser 
465                 470


<210>  5358
<211>  3388
<212>  DNA
<213>  Homo sapiens

<400>  5358
gcagtgagct gtgatcgtgc catcatgcca ctgcaatcta gcctgggcaa tagaatgaga     60

ccctgtctca aaacaaacaa caacaacaaa actttggaat aacaggaaga aaggatacag    120

taaacaagaa tatgggtcaa gtaacctggt ttggttatga aagtcctcgt agcttctggg    180

actatatcag agtggcttgc cggaaagttt cacagaattg tatctgcagc attgaaaata    240

tggaaaatgt cagttcttct agagctaagg gtagagcctg gatcagagta gcactcatgg    300

aaaaacattt atctgaatac atctctacag ctctgagaga cttcaaaaca accaggagat    360

tttatgaaga tggagcaatt gtcttgggtg aagaagcaaa tatgcttgct ggcatgcttc    420

taggactcaa tgctattgat ttcagtttct gcctaaaggg agaggggctg gatggcagtt    480

ttcctgctgt aatagactat acaccatatt tgaagtatat ccaaagttct gatagtatca    540

gcagtgatga ggaggagcta aggactttgg gaagcagtgg tagcgaaagc agtactccag    600

agaatgtcgg acctcctttc ctcatggatg agaacagttg gttcaacaag tgtaagagag    660

ttaaacaaaa gtatcagctt accctggaac agaagggtta ccttgaagaa ctcttacgac    720

ttcgagagaa ccaactatct gaatctgtct cccagaataa aatactactt caaaggattg    780

aagattccga tctggctcat aaactggaga aggaacaatt agaatatata attgtggagc    840

ttcaagatca gctgaaaagt tatcaaagtc ttgaccagtt atcagcagaa gttagccttt    900

ctcagacttc actagatcca ggccagtcac aagaaggaga tggaaaacaa gacacattaa    960

atgtaatgag tgaaggtaag gaagatactc cctcattact tggcctctgt ggatctctaa   1020

cgtcagtggc aagttacaag tctctaacaa gcttaaaatc taatgactac cttgcaagtc   1080

ctacaacaga gatgacaagt ccaggcctaa ctccatcctg aaaatttttg tgtaaaagcc   1140

aaaacttttt atgttgtaaa tgtttaattt acatgtttga ctgctgggaa gacctttgaa   1200

attttatatt gttctggtac atgtctgaaa ttctattgct tggagagaat cccctccaga   1260

taagagattt tgagtgaaaa acataatgat cctgccattt ttcattttta aaattcttac   1320

atttgtcatt gagaaagttc aaaatggaat aggctttaaa aaaaaaaaaa ctttcaaaga   1380

tccgccaaat cattcatagc aaattgtaca tattgttcag ctgattttta tatatttaaa   1440

tacaccttag tggccagaga ctgacttcaa ggttttattc cagagactcc agagacttaa   1500

gctaagtatt ttttcattct ttcagatttt caaaaaaaaa aaaaaaaaaa gttaatttca   1560

ttttttcatt aatgtcttcc taagttctat gctttaaatg ccttgttttt aataacggga   1620

aagttctcag ctgcattttc acagtggctt attcagtttt tctttaatat ttaccatttg   1680

gtatcaattc agcattccac ttaacatttt ataaattcca taggaacatg cctgttttgg   1740

tagttactga cttaatttgt tagtgccaca aggaaaatat tttacagtat tttatgccat   1800

ttaggcaaaa tgaataaact gttttccaag attttcttaa aagattatca atttaaaagt   1860

atgatcaagt atgcctcaaa aactagaaac atttcaaaat gtagaacaaa cgttgaaaaa   1920

ttgttttgcc aggaaagagt tcaagttcag ttaaggattt gagaggcttt taaacaagga   1980

tcagtaggat agttatcata tttacttaat atatgtctga tattcagtgc tggttctttt   2040

tcctgtttgt gcaacaatga agtgtgtcat gtgtgtttta tagcctctat cattaatcac   2100

accagagtct cattttaaaa cattttaatg ttaaaacatc cccacactta tacacaggta   2160

aaattagttt tttttttttt aaagttgtaa tctgtacttt tttttttttg caatttttga   2220

aacagctaca ttaatcccta aaaatcccac catactgaaa atgtatggcg tgtattttct   2280

atagtaagta atatgaggaa aacatgatta gctgtgccaa agaaatttta tacattgttt   2340

acatgatgag gccacagtac ttactgagga cttcatatgg tttttttgtt tattattatt   2400

gagaaaagag ctgaggttac cacattcatt ctttgtgtta gaaatgtagg agtgtggtgg   2460

ttttctgcaa tatttagagc ttagtctcat aatttggaat ttaagataat aagtagtaac   2520

aaggcaagtc ttttatgtaa gacagtcaaa cagtgtcact tcagggacaa aggcctggaa   2580

gcccttaaaa taagttatct tagatgtgcc agaacatatt cagagcttta ttcctttaag   2640

cttaaggctt caatacttgt agaaatgcaa atattcttga gaaatgatac attttttgtt   2700

ctcaatttct caattctaca tacctgatta tgagtgaagt atccaaagca ggttttcatc   2760

agcatggggg atggaaggta ggtataatat gaggacaatg gaaactttgg gagaagggag   2820

tgaggaaatg gataaagaga aatttgaaaa ttttaggctg gacttgagca ctattgctgc   2880

tttcctatga actatcagaa tgtttaaatg ctttatcatt catggtccac tctcaaccaa   2940

catttattat cctttagtaa ttaaacaatg gttttacata catttttata atgtagaagg   3000

aaattcaaga ttccataatc gtaaaatttt tcagatttgt ctaatgtgta atttgtgcat   3060

cttcacatgc tgctaaatgc agatttaaac attacatctg aggatcatga cttttcctcc   3120

tttcttggag atcttggtat aaaattcatc tgctgttata aaatcaggtt tctacagagt   3180

tcgtttcaca ctaaaggtag tttgttactg tttgcatgag gaaaccatgt atgtctcaat   3240

ctttaatttt aggtggtagt gtttattgtt caccctccct cttgcctcca aaagaatgct   3300

gaattatacg ccaatatttc catgtgtatt ctgttgcctt gatgcgtact atacttgttg   3360

catgtatatt aaaaattttg tactatgc                                      3388


<210>  5359
<211>  329
<212>  PRT
<213>  Homo sapiens

<400>  5359

Met Gly Gln Val Thr Trp Phe Gly Tyr Glu Ser Pro Arg Ser Phe Trp 
1               5                   10                  15


Asp Tyr Ile Arg Val Ala Cys Arg Lys Val Ser Gln Asn Cys Ile Cys 
            20                  25                  30


Ser Ile Glu Asn Met Glu Asn Val Ser Ser Ser Arg Ala Lys Gly Arg 
        35                  40                  45


Ala Trp Ile Arg Val Ala Leu Met Glu Lys His Leu Ser Glu Tyr Ile 
    50                  55                  60


Ser Thr Ala Leu Arg Asp Phe Lys Thr Thr Arg Arg Phe Tyr Glu Asp 
65                  70                  75                  80


Gly Ala Ile Val Leu Gly Glu Glu Ala Asn Met Leu Ala Gly Met Leu 
                85                  90                  95


Leu Gly Leu Asn Ala Ile Asp Phe Ser Phe Cys Leu Lys Gly Glu Gly 
            100                 105                 110


Leu Asp Gly Ser Phe Pro Ala Val Ile Asp Tyr Thr Pro Tyr Leu Lys 
        115                 120                 125


Tyr Ile Gln Ser Ser Asp Ser Ile Ser Ser Asp Glu Glu Glu Leu Arg 
    130                 135                 140


Thr Leu Gly Ser Ser Gly Ser Glu Ser Ser Thr Pro Glu Asn Val Gly 
145                 150                 155                 160


Pro Pro Phe Leu Met Asp Glu Asn Ser Trp Phe Asn Lys Cys Lys Arg 
                165                 170                 175


Val Lys Gln Lys Tyr Gln Leu Thr Leu Glu Gln Lys Gly Tyr Leu Glu 
            180                 185                 190


Glu Leu Leu Arg Leu Arg Glu Asn Gln Leu Ser Glu Ser Val Ser Gln 
        195                 200                 205


Asn Lys Ile Leu Leu Gln Arg Ile Glu Asp Ser Asp Leu Ala His Lys 
    210                 215                 220


Leu Glu Lys Glu Gln Leu Glu Tyr Ile Ile Val Glu Leu Gln Asp Gln 
225                 230                 235                 240


Leu Lys Ser Tyr Gln Ser Leu Asp Gln Leu Ser Ala Glu Val Ser Leu 
                245                 250                 255


Ser Gln Thr Ser Leu Asp Pro Gly Gln Ser Gln Glu Gly Asp Gly Lys 
            260                 265                 270


Gln Asp Thr Leu Asn Val Met Ser Glu Gly Lys Glu Asp Thr Pro Ser 
        275                 280                 285


Leu Leu Gly Leu Cys Gly Ser Leu Thr Ser Val Ala Ser Tyr Lys Ser 
    290                 295                 300


Leu Thr Ser Leu Lys Ser Asn Asp Tyr Leu Ala Ser Pro Thr Thr Glu 
305                 310                 315                 320


Met Thr Ser Pro Gly Leu Thr Pro Ser 
                325


<210>  5360
<211>  3140
<212>  DNA
<213>  Homo sapiens

<400>  5360
cgccccctca cgccgccgtc cttctcgcgc ctcgctctgg ccctgcaggt tgtgtttccg     60

cctctacccc gcctccattc cgttgctctc tcagtctcag acccgggctc tcggtccgcc    120

gcttcaggtc ttggcgcagc ctcagagagt tggcgcggct ctgtgttgac caaacctagt    180

ggatgcagtt agcgccggag cccggccccg cccgtcacca gggttattcc cgccttctag    240

gtttgccagg actgccggcc ctgcagctgc cttctgcccc aggtttttgg ctactgatgt    300

tacaaacaat aaaatattgg agcatagagt tgaagaacag actcaaacca ggtttttatt    360

taattagtta aaaatatgga tcctgagaca aggggacaag agattatcaa agtgacacct    420

cttcaacaaa tgcttgcctc atgtactgga gctatactga catcagtaat agtgacaccc    480

ctggatgttg ttaaaattag actccaagcc caaaacaacc cactccccaa aggaaaatgt    540

tttgtatata gtaatggact catggatcat ctatgtgtct gtgaagaggg aggcaacaaa    600

ctatggtata agaagccagg aaatttccag ggaacattgg atgcattttt taaaatcatt    660

cgaaatgagg gcattaaatc tctatggagt ggccttcctc ctaccctagt gatggcagtt    720

cctgccacag ttatttattt tacctgctat gatcaattaa gtgctcttct gagatctaag    780

ttaggagaaa atgaaacctg cataccaatt gttgctggaa ttgtagccag atttggtgca    840

gtaactgtga taagtccact agaattgatt agaaccaaga tgcagtccaa gaagttttct    900

tacgtggaac tgcatcgatt tgtcagcaag aaagtatctg aagatggttg gatttccctt    960

tggaggggct gggctcctac tgttcttaga gatgtacctt tctcagcaat gtactggtat   1020

aactatgaaa ttttaaagaa gtggttatgt gagaaatctg gtttatatga gccaacattt   1080

atgatcaact ttacttcagg ggcattgtct ggttcttttg ctgctgttgc aactttacca   1140

tttgatgtag taaaaacaca aaagcagaca caactttgga catatgaaag tcataaaatt   1200

tctatgcctt tgcatatgtc aacctggatt ataatgaaga acattgttgc taaaaatgga   1260

ttttccggat tattttcagg cctaattcct cgcttaatta aaattgctcc tgcttgtgcc   1320

attatgatca gtacatatga atttggaaag gcttttttcc agaaacaaaa tgttcgaagg   1380

cagcaatact agtgatgctg tttcaacttg aaacaacaac tatagccaaa gaagatggag   1440

actcttaggc aagaatgttt ttcaccatta ttctctcaca atgattttat gtctttcttt   1500

cctataattt aaataaataa tttcagctct acctctaaat cataatttta aaataaattt   1560

tatcttattt ttggtgatat tgaaaaagat attctagaaa tcaccaccat tgagcattct   1620

tgtaaaaata gattactcct tagcatcaaa agcagtctct tgaaagttta atattatatg   1680

tttcagtgta acataatctt actgggagtg tgttgaatac accagaactt tttgaattgt   1740

gtgctgaatg atgtacatag tctagaagaa aaaagcccaa gtcttgtgca catttaaatc   1800

gtgtacataa gtatttccgt atttcagtaa agtagataaa gcactcgtta aatagcattg   1860

tttacatcga ccaaatattg cctgtttcct ttaattcaaa tgcattaggt tcccgcctcc   1920

ctctccttcc ccgccatgtt gctgttttaa ggcttcatat gtattaacat ttctctgatc   1980

aaaattgtgg ctgttttcct tatgaaccat aatataatca tttgtgtgat gtacattgtg   2040

ccatttttga tgactaaatg tctatatttc tgccattcct gtaagagagg gagtttttta   2100

ctgatagtag caaatgttca cttcagtcaa acttgggtgt tcagtggtaa accatatagt   2160

atttagactg gtaaaaatag tttgcacaca ggaatagcct ctgattttta gctctcttgt   2220

aatccaagta tcattgttca tggaattctc taggtcattt ttattgtgtt gttctaacaa   2280

gacagattat tgctacaaca atagttacaa gatatttcta aaatatcctt tgatttttac   2340

tctaagtatg gtagagtaag aggctaaaca agaagctgtt tccttgaaga cattgctttc   2400

agtcaccata catgtctaaa taatttagct tatcattcat tctatgtagg aatgagataa   2460

gaaaggatat gatggcagga aaagaaatgc tattcatttt ttatacttta gttttatttt   2520

cttaggatct atatcctata tatatatatt ttttaaagca ctaatttatt gcagtcttta   2580

ttttagaaaa atgtgaagca tttttttctc ccctaaaatg aatatattta gatgacaagt   2640

ctttagtgct ggtagaggaa ctaattgatt ttgtactata gtaggaaagt gtttatatgt   2700

ttcaccagaa ataaaatatg tagggtttgt atgtaatctt ctgtgtttat cctatgttga   2760

tttaccttaa atttgcaaca tacatatcca cataaatatt catgactttc ttatatttca   2820

ttaaaatgtt ttatggcttc ttaaaatcat cactgtgctt ctaaatattt ttacgtaaaa   2880

tcattgtata atgctatact gtgatataca tgaaagttta tcttgaacag tgctctttaa   2940

caatattaaa tttaaattta tcttggtttt gctatgctta tgggtaattc atagaaaaca   3000

gaaaaaatac tgttcccaaa aggcagttat atatttcagt ttaatatcac ctataagtat   3060

gagaaaggtt tccatgtctc ctacccctca ctgcacttag gaaaattctt atttatgaat   3120

aaagtaagat aagtaaatct                                               3140


<210>  5361
<211>  338
<212>  PRT
<213>  Homo sapiens

<400>  5361

Met Asp Pro Glu Thr Arg Gly Gln Glu Ile Ile Lys Val Thr Pro Leu 
1               5                   10                  15


Gln Gln Met Leu Ala Ser Cys Thr Gly Ala Ile Leu Thr Ser Val Ile 
            20                  25                  30


Val Thr Pro Leu Asp Val Val Lys Ile Arg Leu Gln Ala Gln Asn Asn 
        35                  40                  45


Pro Leu Pro Lys Gly Lys Cys Phe Val Tyr Ser Asn Gly Leu Met Asp 
    50                  55                  60


His Leu Cys Val Cys Glu Glu Gly Gly Asn Lys Leu Trp Tyr Lys Lys 
65                  70                  75                  80


Pro Gly Asn Phe Gln Gly Thr Leu Asp Ala Phe Phe Lys Ile Ile Arg 
                85                  90                  95


Asn Glu Gly Ile Lys Ser Leu Trp Ser Gly Leu Pro Pro Thr Leu Val 
            100                 105                 110


Met Ala Val Pro Ala Thr Val Ile Tyr Phe Thr Cys Tyr Asp Gln Leu 
        115                 120                 125


Ser Ala Leu Leu Arg Ser Lys Leu Gly Glu Asn Glu Thr Cys Ile Pro 
    130                 135                 140


Ile Val Ala Gly Ile Val Ala Arg Phe Gly Ala Val Thr Val Ile Ser 
145                 150                 155                 160


Pro Leu Glu Leu Ile Arg Thr Lys Met Gln Ser Lys Lys Phe Ser Tyr 
                165                 170                 175


Val Glu Leu His Arg Phe Val Ser Lys Lys Val Ser Glu Asp Gly Trp 
            180                 185                 190


Ile Ser Leu Trp Arg Gly Trp Ala Pro Thr Val Leu Arg Asp Val Pro 
        195                 200                 205


Phe Ser Ala Met Tyr Trp Tyr Asn Tyr Glu Ile Leu Lys Lys Trp Leu 
    210                 215                 220


Cys Glu Lys Ser Gly Leu Tyr Glu Pro Thr Phe Met Ile Asn Phe Thr 
225                 230                 235                 240


Ser Gly Ala Leu Ser Gly Ser Phe Ala Ala Val Ala Thr Leu Pro Phe 
                245                 250                 255


Asp Val Val Lys Thr Gln Lys Gln Thr Gln Leu Trp Thr Tyr Glu Ser 
            260                 265                 270


His Lys Ile Ser Met Pro Leu His Met Ser Thr Trp Ile Ile Met Lys 
        275                 280                 285


Asn Ile Val Ala Lys Asn Gly Phe Ser Gly Leu Phe Ser Gly Leu Ile 
    290                 295                 300


Pro Arg Leu Ile Lys Ile Ala Pro Ala Cys Ala Ile Met Ile Ser Thr 
305                 310                 315                 320


Tyr Glu Phe Gly Lys Ala Phe Phe Gln Lys Gln Asn Val Arg Arg Gln 
                325                 330                 335


Gln Tyr 



<210>  5362
<211>  1536
<212>  DNA
<213>  Homo sapiens

<400>  5362
cgccccctca cgccgccgtc cttctcgcgc ctcgctctgg ccctgcaggt tgtgtttccg     60

cctctacccc gcctccattc cgttgctctc tcagtctcag acccgggctc tcggtccgcc    120

gcttcaggtc ttggcgcagc ctcagagagt tggcgcggct ctgtgttgac caaacctagt    180

ggatgcagtt agcgccggag cccggccccg cccgtcacca gggttattcc cgccttctag    240

gtttgccagg actgccggcc ctgcagctgc cttctgcccc aggtttttgg ctactgatgt    300

tacaaacaat aaaatattgg agcatagagt tgaagaacag actcaaacca ggtttttatt    360

taattagtta aaaatatgga tcctgagaca aggggacaag agattatcaa agtgacacct    420

cttcaacaaa tgcttgcctc atgtactgga gctatactga catcagtaat agtgacaccc    480

ctggatgttg ttaaaattag actccaagcc caaaacaacc cactccccaa aggaaaatgt    540

tttgtatata gtaatggact catggatcat ctatgtgtct gtgaagaggg aggcaacaaa    600

ctatggtata agaagccagg aaatttccag ggaacattgg atgcattttt taaaatcatt    660

cgaaatgagg gcattaaatc tctatggagt ggccttcctc ctaccctagt gatggcagtt    720

cctgccacag ttatttattt tacctgctat gatcaattaa gtgctcttct gagatctaag    780

ttaggagaaa atgaaacctg cataccaatt gttgctggaa ttgtagccag atttggtgca    840

gtaactgtga taagtccact agaattgatt agaaccaaga tgcagtccaa gaagttttct    900

tacgtggaac tgcatcgatt tgtcagcaag aaagtatctg aagatggttg gatttccctt    960

tggaggggct gggctcctac tgttcttaga gatgtacctt tctcagcaat gtactggtat   1020

aactatgaaa ttttaaagaa gtggttatgt gagaaatctg gtttatatga gccaacattt   1080

atgatcaact ttacttcagg ggcattgtct ggttcttttg ctgctgttgc aactttacca   1140

tttgatgtag taaaaacaca aaagcagaca caactttgga catatgaaag tcataaaatt   1200

tctatgcctt tgcatatgtc aacctggatt ataatgaaga acattgttgc taaaaatgga   1260

ttttccggat tattttcagg cctaattcct cgcttaatta aaattgctcc tgcttgtgcc   1320

attatgatca gtacatatga atttggaaag gcttttttcc agaaacaaaa tgttcgaagg   1380

cagcaatact agtgatgctg tttcaacttg aaacaacaac tatagccaaa gaagatggag   1440

actcttaggc aagaatgttt ttcaccatta ttctctcaca atgattttat gtctttcttt   1500

cctataattt aaataaataa tttcagctct acctct                             1536


<210>  5363
<211>  338
<212>  PRT
<213>  Homo sapiens

<400>  5363

Met Asp Pro Glu Thr Arg Gly Gln Glu Ile Ile Lys Val Thr Pro Leu 
1               5                   10                  15


Gln Gln Met Leu Ala Ser Cys Thr Gly Ala Ile Leu Thr Ser Val Ile 
            20                  25                  30


Val Thr Pro Leu Asp Val Val Lys Ile Arg Leu Gln Ala Gln Asn Asn 
        35                  40                  45


Pro Leu Pro Lys Gly Lys Cys Phe Val Tyr Ser Asn Gly Leu Met Asp 
    50                  55                  60


His Leu Cys Val Cys Glu Glu Gly Gly Asn Lys Leu Trp Tyr Lys Lys 
65                  70                  75                  80


Pro Gly Asn Phe Gln Gly Thr Leu Asp Ala Phe Phe Lys Ile Ile Arg 
                85                  90                  95


Asn Glu Gly Ile Lys Ser Leu Trp Ser Gly Leu Pro Pro Thr Leu Val 
            100                 105                 110


Met Ala Val Pro Ala Thr Val Ile Tyr Phe Thr Cys Tyr Asp Gln Leu 
        115                 120                 125


Ser Ala Leu Leu Arg Ser Lys Leu Gly Glu Asn Glu Thr Cys Ile Pro 
    130                 135                 140


Ile Val Ala Gly Ile Val Ala Arg Phe Gly Ala Val Thr Val Ile Ser 
145                 150                 155                 160


Pro Leu Glu Leu Ile Arg Thr Lys Met Gln Ser Lys Lys Phe Ser Tyr 
                165                 170                 175


Val Glu Leu His Arg Phe Val Ser Lys Lys Val Ser Glu Asp Gly Trp 
            180                 185                 190


Ile Ser Leu Trp Arg Gly Trp Ala Pro Thr Val Leu Arg Asp Val Pro 
        195                 200                 205


Phe Ser Ala Met Tyr Trp Tyr Asn Tyr Glu Ile Leu Lys Lys Trp Leu 
    210                 215                 220


Cys Glu Lys Ser Gly Leu Tyr Glu Pro Thr Phe Met Ile Asn Phe Thr 
225                 230                 235                 240


Ser Gly Ala Leu Ser Gly Ser Phe Ala Ala Val Ala Thr Leu Pro Phe 
                245                 250                 255


Asp Val Val Lys Thr Gln Lys Gln Thr Gln Leu Trp Thr Tyr Glu Ser 
            260                 265                 270


His Lys Ile Ser Met Pro Leu His Met Ser Thr Trp Ile Ile Met Lys 
        275                 280                 285


Asn Ile Val Ala Lys Asn Gly Phe Ser Gly Leu Phe Ser Gly Leu Ile 
    290                 295                 300


Pro Arg Leu Ile Lys Ile Ala Pro Ala Cys Ala Ile Met Ile Ser Thr 
305                 310                 315                 320


Tyr Glu Phe Gly Lys Ala Phe Phe Gln Lys Gln Asn Val Arg Arg Gln 
                325                 330                 335


Gln Tyr 



<210>  5364
<211>  748
<212>  DNA
<213>  Homo sapiens

<400>  5364
ggaaaaaatg tgatttgtga accattgtaa gtatatttta atatgtaaac atttacataa     60

ctattttaaa aggcttatag agttaaaagt tcaaaattca ttttctttat tcaaatttaa    120

ttttttattc tattttaaaa gcgtttgctg gaaattttta aatgctcact agatacttga    180

gaatttctgc tttgacatat gtgttgtatc ttcttgtgat gtaaaggaat aatagaacac    240

aaaggagcgt gagaaattgt gaatgctggt agtggagtca gagaggcttg gttggaattg    300

tggctctgca actagtagct gtgtgacctc aggaaagtaa gggaattttt ctgaggcttt    360

ttacttttga gtatagtgag aaatacatat ctatttgctt taatgaaaac ttaaaaatat    420

atatattatt tcattttaaa gttcggttat tgttttcatt atccttaaat aatatactaa    480

taagaagaat gtaaaaatat tttaggaaaa attaacaggt tgattgaaat taatcaattt    540

tactttctga tagtttgctg ctgttgcaac tttaccattt gatgtagtaa aaacacaaaa    600

gcagacacaa ctttggacat atgaaagtca taaaagccta attcctcgct taattaaaat    660

tgctcctgct tgtgccatta tgatcagtac atatgaattt ggaaaggctt ttttccagaa    720

acaaaatgtt cgaaggcagc aatactag                                       748


<210>  5365
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  5365

Phe Val Asn His Cys Lys Tyr Ile Leu Ile Cys Lys His Leu His Asn 
1               5                   10                  15


Tyr Phe Lys Arg Leu Ile Glu Leu Lys Val Gln Asn Ser Phe Ser Leu 
            20                  25                  30


Phe Lys Phe Asn Phe Leu Phe Tyr Phe Lys Ser Val Cys Trp Lys Phe 
        35                  40                  45


Leu Asn Ala His 
    50


<210>  5366
<211>  858
<212>  DNA
<213>  Homo sapiens

<400>  5366
aaataagcga gatgttatta ttagctaaaa taaacccttt gaaggagaca gcactggtct     60

aatttatttc aagaatagcg tatccattca gaaaggtagt aataactcag gacactgcta    120

gggagaatga gctgttttcc tcagaaactc cttttagaaa aaaaaagttt taaaactatt    180

tacaataaaa tgtgaatgaa aaaatggttg tgaggacttt tctttggcat tggatacccc    240

atgaaggttt ctatacactt tttaagagat aggggtctca cttaagagtt caagaccagg    300

ctggtcttga actcttaagc tcaagagatc gatcttccca cctcagcctc ccaagtagct    360

gtcttttaaa aatttcatta tgaaaaattt ttaagaccta gaaaaagttt aaaaaataac    420

taccatcaag tttaagaaac aagcattatc aagtcaggag aaaccttcag tacattcctc    480

cttaattgca tccagtccta tacatcttta aacatacagc ctttttctgt ttattatttt    540

taatgaatct aactattaaa aataaaactt aaagtagctt tttaggtaaa caaacctctt    600

cttatggtaa agaaatgata tatccgcaag ggccatggac actatgttat ctgtagtagg    660

aattattaaa ttgttattta taatagcatt atttctttat tttaacattt agtttctatg    720

cctttgcata tgtcaacctg gattataatg aagaacattg ttgctaaaaa tggattttcc    780

ggattatttt caggcctaat tcctcgctta attaaaattg ctcctgcttg tgccattatg    840

atcagtacat atgaattt                                                  858


<210>  5367
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  5367

Met Pro Leu His Met Ser Thr Trp Ile Ile Met Lys Asn Ile Val Ala 
1               5                   10                  15


Lys Asn Gly Phe Ser Gly Leu Phe Ser Gly Leu Ile Pro Arg Leu Ile 
            20                  25                  30


Lys Ile Ala Pro Ala Cys Ala Ile Met Ile Ser Thr Tyr Glu 
        35                  40                  45


<210>  5368
<211>  702
<212>  DNA
<213>  Homo sapiens

<400>  5368
cttctcgcgc ctcgctctgg ccctgcaggt tgtgtttccg cctctacccc gcctccattc     60

cgttgctctc tcagtctcag acccgggctc tcggtccgcc gcttcaggtc ttggcgcagc    120

ctcagagagt tggcgcggct ctgtgttgac caaacctagt ggatgcagtt agcgccggag    180

cccggccccg cccgtcacca gggttattcc cgccttctag gtttgccagg actgccggcc    240

ctgcagctgc cttctgcccc aggtttttgg ctactgatgt tacaaacaat aaaatattgg    300

agcatagagt tgaagaacag actcaaacca ggctggagtg cagtaatgcg atcttggctc    360

attgcaactt ctgcctcctg ggttaaaggg attctcatgc ctcagtcccc cacggaactg    420

ggactacagg tttttattta attagttaaa aatatggatc ctgagacaag gggacaagag    480

attatcaaag tgacacctct tcaacaaatg cttgcctcat gtactggagc tatactgaca    540

tcagtaatag ataccactcg ctaattgaaa cttaacatat cttcatagtg acacccctgg    600

atgttgttaa aattagactc caagcccaaa acaacccact ccccaaagga aaatgttttg    660

tatatagtaa tggactcatg gatcatctat gtgtctgtga ag                       702


<210>  5369
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  5369

Met Gln Leu Ala Pro Glu Pro Gly Pro Ala Arg His Gln Gly Tyr Ser 
1               5                   10                  15


Arg Leu Leu Gly Leu Pro Gly Leu Pro Ala Leu Gln Leu Pro Ser Ala 
            20                  25                  30


Pro Gly Phe Trp Leu Leu Met Leu Gln Thr Ile Lys Tyr Trp Ser Ile 
        35                  40                  45


Glu Leu Lys Asn Arg Leu Lys Pro Gly Trp Ser Ala Val Met Arg Ser 
    50                  55                  60


Trp Leu Ile Ala Thr Ser Ala Ser Trp Val Lys Gly Ile Leu Met Pro 
65                  70                  75                  80


Gln Ser Pro Thr Glu Leu Gly Leu Gln Val Phe Ile 
                85                  90


<210>  5370
<211>  3256
<212>  DNA
<213>  Homo sapiens

<400>  5370
ctctctgagg ctgcgccaag acctgaagcg gcggaccgag agcccgggtc tgagactgag     60

agagcaacgg aatggaggcg gggtagaggc ggaaacacaa cctgcagggc cagagcgagg    120

cgcgagaagg acggcggcgt gagggggcgg ggcgcgcagc gcgagaaggc aggcacgagg    180

ggcgagcgcg aggcggggca cggcgcgtgg cgtgagacgg ggcggggcgc gcgtatcggc    240

gccgcggccg cgtgacgcgt tttcaaatct tcaaccgccg cagcccactc gtttgtgctt    300

tgcgccttcc tcctccgcgc cttggagccg gatccggccc cggaaacccg acctgcagac    360

gcggtacctc tactgcgtag aggccgtagc tggcggaagg agagaggcgg ccgtcctgtc    420

aacaggccgg gggaagccgt gctttcgcgg ctgcccggtg cgacactttc tccggaccca    480

gcatgtaggt gccgggcgac tgccatgaac tccggagcca tgaggatcca cagtaaagga    540

catttccagg gtggaatcca agtcaaaaat gaaaaaaaca gaccatctct gaaatctctg    600

aaaactgata acaggccaga aaaatccaaa tgtaagccac tttggggaaa agtattttac    660

cttgacttac cttctgtcac catatctgaa aaacttcaaa aggacattaa ggatctggga    720

gggcgagttg aagaatttct cagcaaagat atcagttatc ttatttcaaa taagaaggaa    780

gctaaatttg cacaaacctt gggtcgaatt tctcctgtac caagtccaga atctgcatat    840

actgcagaaa ccacttcacc tcatcccagc catgatggaa gttcatttaa gtcaccagac    900

acagtgtgtt taagcagagg aaaattatta gttgaaaaag ctatcaagga ccatgatttt    960

attccttcaa atagtatatt atcaaatgcc ttgtcatggg gagtaaaaat tcttcatatt   1020

gatgacatta gatactacat tgaacaaaag aaaaaagagt tgtatttact caagaaatca   1080

agtacttcag taagagatgg gggcaaaaga gttggtagtg gtgcacaaaa aacaagaaca   1140

ggaagactca aaaagccttt tgtaaaggtg gaagatatga gccaaagccc tgcagtccat   1200

ttgatgtaga caagccatct agtatgcaaa agcaaactca ggttaaacta agaatccaaa   1260

cagatggcga taagtatggt ggaacctcaa ttcaactcca gttgaaagag aagaagaaaa   1320

aaggatattg tgaatgttgc ttgcagaaat atgaagatct agaaactcac cttctaagtg   1380

agcaacacag aaactttgca cagagtaacc agtatcaagt tgttgatgat attgtatcta   1440

agttagtttt tgactttgtg gaatatgaaa aggacacacc taaaaagaaa agaataaaat   1500

acagtgttgg atccctttct cctgtttctg caagtgtcct gaaaaagact gaacaaaagg   1560

aaaaagtgga attgcaacat atttctcaga aagattgcca ggaagatgat acaacagtga   1620

aggagcagaa tttcctgtat aaagagaccc aggaaactga aaaaaagctc ctgtttattt   1680

cagagcccat cccccaccct tcaaatgaat tgagagggct taatgagaaa atgagtaata   1740

aatgttccat gttaagtaca gctgaagatg acataagaca gaattttaca cagctacctc   1800

tacataaaaa caaacaggaa tgcattcttg acatttccga acacacatta agtgaaaatg   1860

acttagaaga actaagggta gatcactata aatgtaacat acaggcatct gtacatgttt   1920

ctgatttcag tacagataat agtggatctc aaccaaaaca gaagtcagat actgtgcttt   1980

ttccagcaaa ggatctcaag gaaaaggacc ttcattcaat atttactcat gattctggtc   2040

tgataacaat aaacagttca caagagcacc taactgttca ggcaaaggct ccattccata   2100

ctcctcctga ggaacccaat gaatgtgact tcaagaatat ggatagttta ccttctggta   2160

aaatacatcg aaaagtgaaa ataatattag gacgaaatag aaaagaaaat ctggaaccaa   2220

atgctgaatt tgataaaaga actgaattta ttacacaaga agaaaacaga atttgtagtt   2280

caccggtaca gtctttacta gacttgtttc agactagtga agagaaatca gaatttttgg   2340

gtttcacaag ctacacagaa aagagtggta tatgcaatgt tttagatatt tgggaagagg   2400

aaaattcaga taatctgtta acagcgtttt tctcgtcccc ttcaacttct acatttactg   2460

gcttttagaa tttaaaaaat gcatactttt cagaagtgat aaggatcata ttcttgaaat   2520

ttttataaat atgtatggaa attcttagga tttttttacc agctttgttt acagacccaa   2580

atgtaaatat taaaaataaa tatttgcaat tttctacaga attgaatacc tgttaaagaa   2640

aaattacaga ataaacttgt gactggtctt gttttacatt atatatatgt tcgtaattgt   2700

ttcctgagaa ttacaatgaa taataatttg ctttgtcact gaaaaccacc agtgaagtgc   2760

aatttgggga atatcaaact tagcattata catttggata ttctagttgt attgtaaatt   2820

ttaaaagatt atcaggataa catgaccttg ccttgaaaaa cctaaatttc atacagaaag   2880

gaaaaataca tttctatgct tgaattctgg aaatcatcag aaatattgac acttgagggt   2940

cactggtgga ccatgctagt attttggtgc tgagtaatta gattatgtat aggggtaact   3000

ggaagccatg aaggaaggac ttaaccaggc taccaagtgg aatataattt atctgctatt   3060

tttaattact taccttgtaa ataactttaa taatattcaa aagttgactc tcctgtggct   3120

catgccacag gatcccagca ctttgggagg ccgaggcagg ctgatcacga ggtcagaaga   3180

tcaagaccat cctggccaac atggtgaaac cttgtctact aaaaatacaa aaaattagct   3240

gggcatggcg gcatgc                                                   3256


<210>  5371
<211>  414
<212>  PRT
<213>  Homo sapiens

<400>  5371

Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln Thr Asp Gly Asp 
1               5                   10                  15


Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys Glu Lys Lys Lys 
            20                  25                  30


Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu Asp Leu Glu Thr 
        35                  40                  45


His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln Ser Asn Gln Tyr 
    50                  55                  60


Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe Asp Phe Val Glu 
65                  70                  75                  80


Tyr Glu Lys Asp Thr Pro Lys Lys Lys Arg Ile Lys Tyr Ser Val Gly 
                85                  90                  95


Ser Leu Ser Pro Val Ser Ala Ser Val Leu Lys Lys Thr Glu Gln Lys 
            100                 105                 110


Glu Lys Val Glu Leu Gln His Ile Ser Gln Lys Asp Cys Gln Glu Asp 
        115                 120                 125


Asp Thr Thr Val Lys Glu Gln Asn Phe Leu Tyr Lys Glu Thr Gln Glu 
    130                 135                 140


Thr Glu Lys Lys Leu Leu Phe Ile Ser Glu Pro Ile Pro His Pro Ser 
145                 150                 155                 160


Asn Glu Leu Arg Gly Leu Asn Glu Lys Met Ser Asn Lys Cys Ser Met 
                165                 170                 175


Leu Ser Thr Ala Glu Asp Asp Ile Arg Gln Asn Phe Thr Gln Leu Pro 
            180                 185                 190


Leu His Lys Asn Lys Gln Glu Cys Ile Leu Asp Ile Ser Glu His Thr 
        195                 200                 205


Leu Ser Glu Asn Asp Leu Glu Glu Leu Arg Val Asp His Tyr Lys Cys 
    210                 215                 220


Asn Ile Gln Ala Ser Val His Val Ser Asp Phe Ser Thr Asp Asn Ser 
225                 230                 235                 240


Gly Ser Gln Pro Lys Gln Lys Ser Asp Thr Val Leu Phe Pro Ala Lys 
                245                 250                 255


Asp Leu Lys Glu Lys Asp Leu His Ser Ile Phe Thr His Asp Ser Gly 
            260                 265                 270


Leu Ile Thr Ile Asn Ser Ser Gln Glu His Leu Thr Val Gln Ala Lys 
        275                 280                 285


Ala Pro Phe His Thr Pro Pro Glu Glu Pro Asn Glu Cys Asp Phe Lys 
    290                 295                 300


Asn Met Asp Ser Leu Pro Ser Gly Lys Ile His Arg Lys Val Lys Ile 
305                 310                 315                 320


Ile Leu Gly Arg Asn Arg Lys Glu Asn Leu Glu Pro Asn Ala Glu Phe 
                325                 330                 335


Asp Lys Arg Thr Glu Phe Ile Thr Gln Glu Glu Asn Arg Ile Cys Ser 
            340                 345                 350


Ser Pro Val Gln Ser Leu Leu Asp Leu Phe Gln Thr Ser Glu Glu Lys 
        355                 360                 365


Ser Glu Phe Leu Gly Phe Thr Ser Tyr Thr Glu Lys Ser Gly Ile Cys 
    370                 375                 380


Asn Val Leu Asp Ile Trp Glu Glu Glu Asn Ser Asp Asn Leu Leu Thr 
385                 390                 395                 400


Ala Phe Phe Ser Ser Pro Ser Thr Ser Thr Phe Thr Gly Phe 
                405                 410


<210>  5372
<211>  3916
<212>  DNA
<213>  Homo sapiens

<400>  5372
ctctctgagg ctgcgccaag acctgaagcg gcggaccgag agcccgggtc tgagactgag     60

agagcaacgg aatggaggcg gggtagaggc ggaaacacaa cctgcagggc cagagcgagg    120

cgcgagaagg acggcggcgt gagggggcgg ggcgcgcagc gcgagaaggc aggcacgagg    180

ggcgagcgcg aggcggggca cggcgcgtgg cgtgagacgg ggcggggcgc gcgtatcggc    240

gccgcggccg cgtgacgcgt tttcaaatct tcaaccgccg cagcccactc gtttgtgctt    300

tgcgccttcc tcctccgcgc cttggagccg gatccggccc cggaaacccg acctgcagac    360

gcggtacctc tactgcgtag aggccgtagc tggcggaagg agagaggcgg ccgtcctgtc    420

aacaggccgg gggaagccgt gctttcgcgg ctgcccggtg cgacactttc tccggaccca    480

gcatgtaggt gccgggcgac tgccatgaac tccggagcca tgaggatcca cagtaaagga    540

catttccagg gtggaatcca agtcaaaaat gaaaaaaaca gaccatctct gaaatctctg    600

aaaactgata acaggccaga aaaatccaaa tgtaagccac tttggggaaa agtattttac    660

cttgacttac cttctgtcac catatctgaa aaacttcaaa aggacattaa ggatctggga    720

gggcgagttg aagaatttct cagcaaagat atcagttatc ttatttcaaa taagaaggaa    780

gctaaatttg cacaaacctt gggtcgaatt tctcctgtac caagtccaga atctgcatat    840

actgcagaaa ccacttcacc tcatcccagc catgatggaa gttcatttaa gtcaccagac    900

acagtgtgtt taagcagagg aaaattatta gttgaaaaag ctatcaagga ccatgatttt    960

attccttcaa atagtatatt atcaaatgcc ttgtcatggg gagtaaaaat tcttcatatt   1020

gatgacatta gatactacat tgaacaaaag aaaaaagagt tgtatttact caagaaatca   1080

agtacttcag taagagatgg gggcaaaaga gttggtagtg gtgcacaaaa aacaagaaca   1140

ggaagactca aaaagccttt tgtaaaggtg gaagatatga gccaacttta taggccattt   1200

tatcttcagc tgaccaatat gccttttata aattattcta ttcagaagcc ctgcagtcca   1260

tttgatgtag acaagccatc tagtatgcaa aagcaaactc aggttaaact aagaatccaa   1320

acagatggcg ataagtatgg tggaacctca attcaactcc agttgaaaga gaagaagaaa   1380

aaaggatatt gtgaatgttg cttgcagaaa tatgaagatc tagaaactca ccttctaagt   1440

gagcaacaca gaaactttgc acagagtaac cagtatcaag ttgttgatga tattgtatct   1500

aagttagttt ttgactttgt ggaatatgaa aaggacacac ctaaaaagaa aagaataaaa   1560

tacagtgttg gatccctttc tcctgtttct gcaagtgtcc tgaaaaagac tgaacaaaag   1620

gaaaaagtgg aattgcaaca tatttctcag aaagattgcc aggaagatga tacaacagtg   1680

aaggagcaga atttcctgta taaagagacc caggaaactg aaaaaaagct cctgtttatt   1740

tcagagccca tcccccaccc ttcaaatgaa ttgagagggc ttaatgagaa aatgagtaat   1800

aaatgttcca tgttaagtac agctgaagat gacataagac agaattttac acagctacct   1860

ctacataaaa acaaacagga atgcattctt gacatttccg aacacacatt aagtgaaaat   1920

gacttagaag aactaagggt agatcactat aaatgtaaca tacaggcatc tgtacatgtt   1980

tctgatttca gtacagataa tagtggatct caaccaaaac agaagtcaga tactgtgctt   2040

tttccagcaa aggatctcaa ggaaaaggac cttcattcaa tatttactca tgattctggt   2100

ctgataacaa taaacagttc acaagagcac ctaactgttc aggcaaaggc tccattccat   2160

actcctcctg aggaacccaa tgaatgtgac ttcaagaata tggatagttt accttctggt   2220

aaaatacatc gaaaagtgaa aataatatta ggacgaaata gaaaagaaaa tctggaacca   2280

aatgctgaat ttgataaaag aactgaattt attacacaag aagaaaacag aatttgtagt   2340

tcaccggtac agtctttact agacttgttt cagactagtg aagagaaatc agaatttttg   2400

ggtttcacaa gctacacaga aaagagtggt atatgcaatg ttttagatat ttgggaagag   2460

gaaaattcag ataatctgtt aacagcgttt ttctcgtccc cttcaacttc tacatttact   2520

ggcttttaga atttaaaaaa tgcatacttt tcagaagtga taaggatcat attcttgaaa   2580

tttttataaa tatgtatgga aattcttagg atttttttac cagctttgtt tacagaccca   2640

aatgtaaata ttaaaaataa atatttgcaa ttttctacag aattgaatac ctgttaaaga   2700

aaaattacag aataaacttg tgactggtct tgttttacat tatatatatg ttcgtaattg   2760

tttcctgaga attacaatga ataataattt gctttgtcac tgaaaaccac cagtgaagtg   2820

caatttgggg aatatcaaac ttagcattat acatttggat attctagttg tattgtaaat   2880

tttaaaagat tatcaggata acatgacctt gccttgaaaa acctaaattt catacagaaa   2940

ggaaaaatac atttctatgc ttgaattctg gaaatcatca gaaatattga cacttgaggg   3000

tcactggtgg accatgctag tattttggtg ctgagtaatt agattatgta taggggtaac   3060

tggaagccat gaaggaagga cttaaccagg ctaccaagtg gaatataatt tatctgctat   3120

ttttaattac ttaccttgta aataacttta ataatattca aaagttgact ctcctgtggc   3180

tcatgccaca ggatcccagc actttgggag gccgaggcag gctgatcacg aggtcagaag   3240

atcaagacca tcctggccaa catggtgaaa ccttgtctac taaaaataca aaaaattagc   3300

tgggcatggc ggcatgcgcc tgtagtccca gctactccct ccagaggctg agaattgctt   3360

gaacctggga agtgcaggtt gcagtgagcc aagattgtgc cactgtattc cagactgggt   3420

gacagagtga gactccatct caaaaaaaaa aaagttgact ctacccccta atttggtagg   3480

agatgaagga gaaaaggatg gcattgaatt atagatacag ttttgggata tatacaagga   3540

ttgccttgat ctggcactta ctgatacaag catttggaga agagaaaatt caaatataag   3600

aaatttcaat ttgaatctgt ggatataagg catttgcctt tgagtatgtt cttgtaggag   3660

taagactacc accagtgaca ttcaattggt tctattgcat agtacatgaa tctattgtca   3720

ctaaaaatta ggttactaat cttaattttt ttgaaatata tgattctcag tacaggacta   3780

attcatatgc ttttcctgca tacattattt tgatcatttg gataacatca atgaacactg   3840

gctttttaac acctttgttt ttcataccag tacctgaagt aggctcaata aaagagtctt   3900

tacagtgcat acacgc                                                   3916


<210>  5373
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  5373

Met Asn Ser Gly Ala Met Arg Ile His Ser Lys Gly His Phe Gln Gly 
1               5                   10                  15


Gly Ile Gln Val Lys Asn Glu Lys Asn Arg Pro Ser Leu Lys Ser Leu 
            20                  25                  30


Lys Thr Asp Asn Arg Pro Glu Lys Ser Lys Cys Lys Pro Leu Trp Gly 
        35                  40                  45


Lys Val Phe Tyr Leu Asp Leu Pro Ser Val Thr Ile Ser Glu Lys Leu 
    50                  55                  60


Gln Lys Asp Ile Lys Asp Leu Gly Gly Arg Val Glu Glu Phe Leu Ser 
65                  70                  75                  80


Lys Asp Ile Ser Tyr Leu Ile Ser Asn Lys Lys Glu Ala Lys Phe Ala 
                85                  90                  95


Gln Thr Leu Gly Arg Ile Ser Pro Val Pro Ser Pro Glu Ser Ala Tyr 
            100                 105                 110


Thr Ala Glu Thr Thr Ser Pro His Pro Ser His Asp Gly Ser Ser Phe 
        115                 120                 125


Lys Ser Pro Asp Thr Val Cys Leu Ser Arg Gly Lys Leu Leu Val Glu 
    130                 135                 140


Lys Ala Ile Lys Asp His Asp Phe Ile Pro Ser Asn Ser Ile Leu Ser 
145                 150                 155                 160


Asn Ala Leu Ser Trp Gly Val Lys Ile Leu His Ile Asp Asp Ile Arg 
                165                 170                 175


Tyr Tyr Ile Glu Gln Lys Lys Lys Glu Leu Tyr Leu Leu Lys Lys Ser 
            180                 185                 190


Ser Thr Ser Val Arg Asp Gly Gly Lys Arg Val Gly Ser Gly Ala Gln 
        195                 200                 205


Lys Thr Arg Thr Gly Arg Leu Lys Lys Pro Phe Val Lys Val Glu Asp 
    210                 215                 220


Met Ser Gln Leu Tyr Arg Pro Phe Tyr Leu Gln Leu Thr Asn Met Pro 
225                 230                 235                 240


Phe Ile Asn Tyr Ser Ile Gln Lys Pro Cys Ser Pro Phe Asp Val Asp 
                245                 250                 255


Lys Pro Ser Ser Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln 
            260                 265                 270


Thr Asp Gly Asp Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys 
        275                 280                 285


Glu Lys Lys Lys Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu 
    290                 295                 300


Asp Leu Glu Thr His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln 
305                 310                 315                 320


Ser Asn Gln Tyr Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe 
                325                 330                 335


Asp Phe Val Glu Tyr Glu Lys Asp Thr Pro Lys Lys Lys Arg Ile Lys 
            340                 345                 350


Tyr Ser Val Gly Ser Leu Ser Pro Val Ser Ala Ser Val Leu Lys Lys 
        355                 360                 365


Thr Glu Gln Lys Glu Lys Val Glu Leu Gln His Ile Ser Gln Lys Asp 
    370                 375                 380


Cys Gln Glu Asp Asp Thr Thr Val Lys Glu Gln Asn Phe Leu Tyr Lys 
385                 390                 395                 400


Glu Thr Gln Glu Thr Glu Lys Lys Leu Leu Phe Ile Ser Glu Pro Ile 
                405                 410                 415


Pro His Pro Ser Asn Glu Leu Arg Gly Leu Asn Glu Lys Met Ser Asn 
            420                 425                 430


Lys Cys Ser Met Leu Ser Thr Ala Glu Asp Asp Ile Arg Gln Asn Phe 
        435                 440                 445


Thr Gln Leu Pro Leu His Lys Asn Lys Gln Glu Cys Ile Leu Asp Ile 
    450                 455                 460


Ser Glu His Thr Leu Ser Glu Asn Asp Leu Glu Glu Leu Arg Val Asp 
465                 470                 475                 480


His Tyr Lys Cys Asn Ile Gln Ala Ser Val His Val Ser Asp Phe Ser 
                485                 490                 495


Thr Asp Asn Ser Gly Ser Gln Pro Lys Gln Lys Ser Asp Thr Val Leu 
            500                 505                 510


Phe Pro Ala Lys Asp Leu Lys Glu Lys Asp Leu His Ser Ile Phe Thr 
        515                 520                 525


His Asp Ser Gly Leu Ile Thr Ile Asn Ser Ser Gln Glu His Leu Thr 
    530                 535                 540


Val Gln Ala Lys Ala Pro Phe His Thr Pro Pro Glu Glu Pro Asn Glu 
545                 550                 555                 560


Cys Asp Phe Lys Asn Met Asp Ser Leu Pro Ser Gly Lys Ile His Arg 
                565                 570                 575


Lys Val Lys Ile Ile Leu Gly Arg Asn Arg Lys Glu Asn Leu Glu Pro 
            580                 585                 590


Asn Ala Glu Phe Asp Lys Arg Thr Glu Phe Ile Thr Gln Glu Glu Asn 
        595                 600                 605


Arg Ile Cys Ser Ser Pro Val Gln Ser Leu Leu Asp Leu Phe Gln Thr 
    610                 615                 620


Ser Glu Glu Lys Ser Glu Phe Leu Gly Phe Thr Ser Tyr Thr Glu Lys 
625                 630                 635                 640


Ser Gly Ile Cys Asn Val Leu Asp Ile Trp Glu Glu Glu Asn Ser Asp 
                645                 650                 655


Asn Leu Leu Thr Ala Phe Phe Ser Ser Pro Ser Thr Ser Thr Phe Thr 
            660                 665                 670


Gly Phe 



<210>  5374
<211>  1037
<212>  DNA
<213>  Homo sapiens

<400>  5374
agacctgaag cggcggaccg agagcccggg tctgagactg agagagcaac ggaatggagg     60

cggggtagag gcggaaacac aacctgcagg gccagagcga ggcgcgagaa ggacggcggc    120

gtgagggggc ggggcgcgca gcgcgagaag gcaggcacga ggggcgagcg cgaggcgggg    180

cacggcgcgt ggcgtgagac ggggcggggc gcgcgtatcg gcgccgcggc cgcgtgacgc    240

gttttcaaat cttcaaccgc cgcagcccac tcgtttgtgc tttgcgcctt cctcctccgc    300

gccttggagc cggatccggc cccggaaacc cgacctgcag acgcggtacc tctactgcgt    360

agaggccgta gctggcggaa ggagagaggc ggccgtcctg tcaacaggcc gggggaagcc    420

gtgctttcgc ggctgcccgg tgcgacactt tctccggacc cagcatgtag gtgccgggcg    480

actgccatga actccggagc catgaggatc cacagtaaag gacatttcca gggtggaatc    540

caagtcaaaa atgaaaaaaa cagaccatct ctgaaatctc tgaaaactga taacaggcca    600

gaaaaatcca aatgtaagcc actttgggga aaagtatttt accttgactt accttctgtc    660

accatatctg aaaaacttca aaaggacatt aaggatctgg gaggggtaag tgaaaaccgt    720

acactggcat agaaggaaaa atttgtaact agtactttct actgtgtaat catttaaatt    780

tttcattttg gaaaacgctt ctattagcac caagcttaac atttttatca gctgtttatc    840

gttaacaaaa aaccatttgt tttaaccttt tgtggactga cagacctttc aggtttctct    900

gattagcagt ctagtgtaaa gttcttagag tgtaagactc ccctgtccta gtggaactgc    960

tcattgactg cttactgtaa tgttggaatg tcctccagat aacagcaatt tcttgattat   1020

gaatcttggg gagctac                                                  1037


<210>  5375
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  5375

Met Asn Ser Gly Ala Met Arg Ile His Ser Lys Gly His Phe Gln Gly 
1               5                   10                  15


Gly Ile Gln Val Lys Asn Glu Lys Asn Arg Pro Ser Leu Lys Ser Leu 
            20                  25                  30


Lys Thr Asp Asn Arg Pro Glu Lys Ser Lys Cys Lys Pro Leu Trp Gly 
        35                  40                  45


Lys Val Phe Tyr Leu Asp Leu Pro Ser Val Thr Ile Ser Glu Lys Leu 
    50                  55                  60


Gln Lys Asp Ile Lys Asp Leu Gly Gly Val Ser Glu Asn Arg Thr Leu 
65                  70                  75                  80


Ala 



<210>  5376
<211>  910
<212>  DNA
<213>  Homo sapiens

<400>  5376
agacctgaag cggcggaccg agagcccggg tctgagactg agagagcaac ggaatggagg     60

cggggtagag gcggaaacac aacctgcagg gccagagcga ggcgcgagaa ggacggcggc    120

gtgagggggc ggggcgcgca gcgcgagaag gcaggcacga ggggcgagcg cgaggcgggg    180

cacggcgcgt ggcgtgagac ggggcggggc gcgcgtatcg gcgccgcggc cgcgtgacgc    240

gttttcaaat cttcaaccgc cgcagcccac tcgtttgtgc tttgcgcctt cctcctccgc    300

gccttggagc cggatccggc cccggaaacc cgacctgcag acgcggtacc tctactgcgt    360

agaggccgta gctggcggaa ggagagaggc ggccgtcctg tcaacaggcc gggggaagcc    420

gtgctttcgc ggctgcccgg tgcgacactt tctccggacc cagcatgtag gtgccgggcg    480

actgccatga actccggagc catgaggatc cacagtaaag gacatttcca gggtggaatc    540

caagtcaaaa atgaaaaaaa cagaccatct ctgaaatctc tgaaaactga taacaggcca    600

gaaaaatcca aataagccct gcagtccatt tgatgtagac aagccatcta gtatgcaaaa    660

gcaaactcag gttaaactaa gaatccaaac agatggcgat aagtatggtg gaacctcaat    720

tcaactccag ttgaaagaga agaagaaaaa aggatattgt gaatgttgct tgcagaaata    780

tgaagatcta gaaactcacc ttctaagtga gcaacacaga aactttgcac agagtaacca    840

gtatcaagtt gttgatgata ttgtatctaa gttagttttt gactttgtgg aatatgaaaa    900

ggacacacct                                                           910


<210>  5377
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  5377

Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln Thr Asp Gly Asp 
1               5                   10                  15


Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys Glu Lys Lys Lys 
            20                  25                  30


Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu Asp Leu Glu Thr 
        35                  40                  45


His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln Ser Asn Gln Tyr 
    50                  55                  60


Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe Asp Phe Val Glu 
65                  70                  75                  80


Tyr Glu Lys Asp Thr 
                85


<210>  5378
<211>  1524
<212>  DNA
<213>  Homo sapiens

<400>  5378
agacctgaag cggcggaccg agagcccggg tctgagactg agagagcaac ggaatggagg     60

cggggtagag gcggaaacac aacctgcagg gccagagcga ggcgcgagaa ggacggcggc    120

gtgagggggc ggggcgcgca gcgcgagaag gcaggcacga ggggcgagcg cgaggcgggg    180

cacggcgcgt ggcgtgagac ggggcggggc gcgcgtatcg gcgccgcggc cgcgtgacgc    240

gttttcaaat cttcaaccgc cgcagcccac tcgtttgtgc tttgcgcctt cctcctccgc    300

gccttggagc cggatccggc cccggaaacc cgacctgcag acgcggtacc tctactgcgt    360

agaggccgta gctggcggaa ggagagaggc ggccgtcctg tcaacaggcc gggggaagcc    420

gtgctttcgc ggctgcccgg tgcgacactt tctccggacc cagcatgtag gtgccgggcg    480

actgccatga actccggagc catgaggatc cacagtaaag gacatttcca gggtggaatc    540

caagtcaaaa atgaaaaaaa cagaccatct ctgaaatctc tgaaaactga taacaggcca    600

gaaaaatcca aatgtaagcc actttgggga aaagtatttt accttgactt accttctgtc    660

accatatctg aaaaacttca aaaggacatt aaggatctgg gagggcgagt tgaagaattt    720

ctcagcaaag atatcagtta tcttatttca aataagaagg aagctaaatt tgcacaaacc    780

ttgggtcgaa tttctcctgt accaagtcca gaatctgcat atactgcaga aaccacttca    840

cctcatccca gccatgatgg aagttcattt aagtcaccag acacagtgtg tttaagcaga    900

ggaaaattat tagttgaaaa agctatcaag gaccatgatt ttattccttc aaatagtata    960

ttatcaaatg ccttgtcatg gggagtaaaa attcttcata ttgatgacat tagatactac   1020

attgaacaaa agaaaaaaga gttgtattta ctcaagaaat caagtacttc agtaagagat   1080

gggggcaaaa gagttggtag tggtgcacaa aaaacaagaa caggaagact caaaaagcct   1140

tttgtaaagg tggaagatat gagccaactt tataggccat tttatcttca gctgaccaat   1200

atgcctttta taaattattc tattcagaag ccctgcagtc catttgatgt agacaagcca   1260

tctagtatgc aaaagcaaac tcaggttaaa ctaagaatcc aaacagatgg cgataagtat   1320

ggtggaacct caattcaact ccagttgaaa gagaagaaga aaaaaggata ttgtgaatgt   1380

tgcttgcaga aatatgaaga tctagaaact caccttctaa gtgagcaaca cagaaacttt   1440

gcacagagta accagtatca agttgttgat gatattgtat ctaagttagt ttttgacttt   1500

gtggaatatg aaaaggacac acct                                          1524


<210>  5379
<211>  345
<212>  PRT
<213>  Homo sapiens

<400>  5379

Met Asn Ser Gly Ala Met Arg Ile His Ser Lys Gly His Phe Gln Gly 
1               5                   10                  15


Gly Ile Gln Val Lys Asn Glu Lys Asn Arg Pro Ser Leu Lys Ser Leu 
            20                  25                  30


Lys Thr Asp Asn Arg Pro Glu Lys Ser Lys Cys Lys Pro Leu Trp Gly 
        35                  40                  45


Lys Val Phe Tyr Leu Asp Leu Pro Ser Val Thr Ile Ser Glu Lys Leu 
    50                  55                  60


Gln Lys Asp Ile Lys Asp Leu Gly Gly Arg Val Glu Glu Phe Leu Ser 
65                  70                  75                  80


Lys Asp Ile Ser Tyr Leu Ile Ser Asn Lys Lys Glu Ala Lys Phe Ala 
                85                  90                  95


Gln Thr Leu Gly Arg Ile Ser Pro Val Pro Ser Pro Glu Ser Ala Tyr 
            100                 105                 110


Thr Ala Glu Thr Thr Ser Pro His Pro Ser His Asp Gly Ser Ser Phe 
        115                 120                 125


Lys Ser Pro Asp Thr Val Cys Leu Ser Arg Gly Lys Leu Leu Val Glu 
    130                 135                 140


Lys Ala Ile Lys Asp His Asp Phe Ile Pro Ser Asn Ser Ile Leu Ser 
145                 150                 155                 160


Asn Ala Leu Ser Trp Gly Val Lys Ile Leu His Ile Asp Asp Ile Arg 
                165                 170                 175


Tyr Tyr Ile Glu Gln Lys Lys Lys Glu Leu Tyr Leu Leu Lys Lys Ser 
            180                 185                 190


Ser Thr Ser Val Arg Asp Gly Gly Lys Arg Val Gly Ser Gly Ala Gln 
        195                 200                 205


Lys Thr Arg Thr Gly Arg Leu Lys Lys Pro Phe Val Lys Val Glu Asp 
    210                 215                 220


Met Ser Gln Leu Tyr Arg Pro Phe Tyr Leu Gln Leu Thr Asn Met Pro 
225                 230                 235                 240


Phe Ile Asn Tyr Ser Ile Gln Lys Pro Cys Ser Pro Phe Asp Val Asp 
                245                 250                 255


Lys Pro Ser Ser Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln 
            260                 265                 270


Thr Asp Gly Asp Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys 
        275                 280                 285


Glu Lys Lys Lys Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu 
    290                 295                 300


Asp Leu Glu Thr His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln 
305                 310                 315                 320


Ser Asn Gln Tyr Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe 
                325                 330                 335


Asp Phe Val Glu Tyr Glu Lys Asp Thr 
            340                 345


<210>  5380
<211>  2723
<212>  DNA
<213>  Homo sapiens

<400>  5380
agacctgaag cggcggaccg agagcccggg tctgagactg agagagcaac ggaatggagg     60

cggggtagag gcggaaacac aacctgcagg gccagagcga ggcgcgagaa ggacggcggc    120

gtgagggggc ggggcgcgca gcgcgagaag gcaggcacga ggggcgagcg cgaggcgggg    180

cacggcgcgt ggcgtgagac ggggcggggc gcgcgtatcg gcgccgcggc cgcgtgacgc    240

gttttcaaat cttcaaccgc cgcagcccac tcgtttgtgc tttgcgcctt cctcctccgc    300

gccttggagc cggatccggc cccggaaacc cgacctgcag acgcggtacc tctactgcgt    360

agaggccgta gctggcggaa ggagagaggc ggccgtcctg tcaacaggcc gggggaagcc    420

gtgctttcgc ggctgcccgg tgcgacactt tctccggacc cagcatgtag gtgccgggcg    480

actgccatga actccggagc catgaggatc cacagtaaag gacatttcca gggtggaatc    540

caagtcaaaa atgaaaaaaa cagaccatct ctgaaatctc tgaaaactga taacaggcca    600

gaaaaatcca aatgtaagcc actttgggga aaagtatttt accttgactt accttctgtc    660

accatatctg aaaaacttca aaaggacatt aaggatctgg gagggcgagt tgaagaattt    720

ctcagcaaag atatcagtta tcttatttca aataagaagg aagctaaatt tgcacaaacc    780

ttgggtcgaa tttctcctgt accaagtcca gaatctgcat atactgcaga aaccacttca    840

cctcatccca gccatgatgg aagttcattt aagtcaccag acacagtgtg tttaagcaga    900

ggaaaattat tagttgaaaa agctatcaag gaccatgatt ttattccttc aaatagtata    960

ttatcaaatg ccttgtcatg gggagtaaaa attcttcata ttgatgacat tagatactac   1020

attgaacaaa agaaaaaaga gttgtattta ctcaagaaat caagtacttc agtaagagat   1080

gggggcaaaa gagttggtag tggtgcacaa aaaacaagaa caggaagact caaaaagcct   1140

tttgtaaagg tggaagatat gagccaactt tataggccat tttatcttca gctgaccaat   1200

atgcctttta taaattattc tattcagaag ccctgcagtc catttgatgt agacaagcca   1260

tctagtatgc aaaagcaaac tcaggttaaa ctaagaatcc aaacagatgg cgataagtat   1320

ggtggaacct caattcaact ccagttgaaa gagaagaaga aaaaaggata ttgtgaatgt   1380

tgcttgcaga aatatgaaga tctagaaact caccttctaa gtgagcaaca cagaaacttt   1440

gcacagagta accagtatca agttgttgat gatattgtat ctaagttagt ttttgacttt   1500

gtggaatatg aaaaggacac acctaaaaag aaaagaataa aatacagtgt tggatccctt   1560

tctcctgttt ctgcaagtgt cctgaaaaag actgaacaaa aggaaaaagt ggaattgcaa   1620

catatttctc agaaagattg ccaggaagat gatacaacag tgaaggagca gaatttcctg   1680

tataaagaga cccaggaaac tgaaaaaaag ctcctgttta tttcagagcc catcccccac   1740

ccttcaaatg aattgagagg gcttaatgag aaaatgagta ataaatgttc catgttaagt   1800

acagctgaag atgacataag acagaatttt acacagctac ctctacataa aaacaaacag   1860

gaatgcattc ttgacatttc cgaacacaca ttaagtgaaa atgacttaga agaactaagg   1920

gtagatcact ataaatgtaa catacaggca tctgtacatg tttctgattt cagtacagat   1980

aatagtggat ctcaaccaaa acagaagtca gatactgtgc tttttccagc aaaggatctc   2040

aaggaaaagg accttcattc aatatttact catgattctg gtctgataac aataaacagt   2100

tcacaagagc acctaactgt tcaggcaaag gctccattcc atactcctcc tgaggaaccc   2160

aatgaatgtg acttcaagaa tatggatagt ttaccttctg gtaaaataca tcgaaaagtg   2220

aaaataatat taggacgaaa tagaaaagaa aatctggaac caaatgctga atttgataaa   2280

agaactgaat ttattacaca agaagaaaac agaatttgta gttcaccggt acagtcttta   2340

ctagacttgt ttcagactag tgaagagaaa tcagaatttt tgggtttcac aagctacaca   2400

gaaaagagtg gtatatgcaa tgttttagat atttgggaag aggaaaattc agataatctg   2460

ttaacagcgt ttttctcgtc cccttcaact tctacattta ctggctttta gaatttaaaa   2520

aatgcatact tttcagaagt gataaggatc atattcttga aatttttata aatatgtatg   2580

gaaattctta ggattttttt accagctttg tttacagacc caaatgtaaa tattaaaaat   2640

aaatatttgc aattttctac agaattgaat acctgttaaa gaaaaattac agaataaact   2700

tgtgactggt cttgttttac att                                           2723


<210>  5381
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  5381

Met Asn Ser Gly Ala Met Arg Ile His Ser Lys Gly His Phe Gln Gly 
1               5                   10                  15


Gly Ile Gln Val Lys Asn Glu Lys Asn Arg Pro Ser Leu Lys Ser Leu 
            20                  25                  30


Lys Thr Asp Asn Arg Pro Glu Lys Ser Lys Cys Lys Pro Leu Trp Gly 
        35                  40                  45


Lys Val Phe Tyr Leu Asp Leu Pro Ser Val Thr Ile Ser Glu Lys Leu 
    50                  55                  60


Gln Lys Asp Ile Lys Asp Leu Gly Gly Arg Val Glu Glu Phe Leu Ser 
65                  70                  75                  80


Lys Asp Ile Ser Tyr Leu Ile Ser Asn Lys Lys Glu Ala Lys Phe Ala 
                85                  90                  95


Gln Thr Leu Gly Arg Ile Ser Pro Val Pro Ser Pro Glu Ser Ala Tyr 
            100                 105                 110


Thr Ala Glu Thr Thr Ser Pro His Pro Ser His Asp Gly Ser Ser Phe 
        115                 120                 125


Lys Ser Pro Asp Thr Val Cys Leu Ser Arg Gly Lys Leu Leu Val Glu 
    130                 135                 140


Lys Ala Ile Lys Asp His Asp Phe Ile Pro Ser Asn Ser Ile Leu Ser 
145                 150                 155                 160


Asn Ala Leu Ser Trp Gly Val Lys Ile Leu His Ile Asp Asp Ile Arg 
                165                 170                 175


Tyr Tyr Ile Glu Gln Lys Lys Lys Glu Leu Tyr Leu Leu Lys Lys Ser 
            180                 185                 190


Ser Thr Ser Val Arg Asp Gly Gly Lys Arg Val Gly Ser Gly Ala Gln 
        195                 200                 205


Lys Thr Arg Thr Gly Arg Leu Lys Lys Pro Phe Val Lys Val Glu Asp 
    210                 215                 220


Met Ser Gln Leu Tyr Arg Pro Phe Tyr Leu Gln Leu Thr Asn Met Pro 
225                 230                 235                 240


Phe Ile Asn Tyr Ser Ile Gln Lys Pro Cys Ser Pro Phe Asp Val Asp 
                245                 250                 255


Lys Pro Ser Ser Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln 
            260                 265                 270


Thr Asp Gly Asp Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys 
        275                 280                 285


Glu Lys Lys Lys Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu 
    290                 295                 300


Asp Leu Glu Thr His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln 
305                 310                 315                 320


Ser Asn Gln Tyr Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe 
                325                 330                 335


Asp Phe Val Glu Tyr Glu Lys Asp Thr Pro Lys Lys Lys Arg Ile Lys 
            340                 345                 350


Tyr Ser Val Gly Ser Leu Ser Pro Val Ser Ala Ser Val Leu Lys Lys 
        355                 360                 365


Thr Glu Gln Lys Glu Lys Val Glu Leu Gln His Ile Ser Gln Lys Asp 
    370                 375                 380


Cys Gln Glu Asp Asp Thr Thr Val Lys Glu Gln Asn Phe Leu Tyr Lys 
385                 390                 395                 400


Glu Thr Gln Glu Thr Glu Lys Lys Leu Leu Phe Ile Ser Glu Pro Ile 
                405                 410                 415


Pro His Pro Ser Asn Glu Leu Arg Gly Leu Asn Glu Lys Met Ser Asn 
            420                 425                 430


Lys Cys Ser Met Leu Ser Thr Ala Glu Asp Asp Ile Arg Gln Asn Phe 
        435                 440                 445


Thr Gln Leu Pro Leu His Lys Asn Lys Gln Glu Cys Ile Leu Asp Ile 
    450                 455                 460


Ser Glu His Thr Leu Ser Glu Asn Asp Leu Glu Glu Leu Arg Val Asp 
465                 470                 475                 480


His Tyr Lys Cys Asn Ile Gln Ala Ser Val His Val Ser Asp Phe Ser 
                485                 490                 495


Thr Asp Asn Ser Gly Ser Gln Pro Lys Gln Lys Ser Asp Thr Val Leu 
            500                 505                 510


Phe Pro Ala Lys Asp Leu Lys Glu Lys Asp Leu His Ser Ile Phe Thr 
        515                 520                 525


His Asp Ser Gly Leu Ile Thr Ile Asn Ser Ser Gln Glu His Leu Thr 
    530                 535                 540


Val Gln Ala Lys Ala Pro Phe His Thr Pro Pro Glu Glu Pro Asn Glu 
545                 550                 555                 560


Cys Asp Phe Lys Asn Met Asp Ser Leu Pro Ser Gly Lys Ile His Arg 
                565                 570                 575


Lys Val Lys Ile Ile Leu Gly Arg Asn Arg Lys Glu Asn Leu Glu Pro 
            580                 585                 590


Asn Ala Glu Phe Asp Lys Arg Thr Glu Phe Ile Thr Gln Glu Glu Asn 
        595                 600                 605


Arg Ile Cys Ser Ser Pro Val Gln Ser Leu Leu Asp Leu Phe Gln Thr 
    610                 615                 620


Ser Glu Glu Lys Ser Glu Phe Leu Gly Phe Thr Ser Tyr Thr Glu Lys 
625                 630                 635                 640


Ser Gly Ile Cys Asn Val Leu Asp Ile Trp Glu Glu Glu Asn Ser Asp 
                645                 650                 655


Asn Leu Leu Thr Ala Phe Phe Ser Ser Pro Ser Thr Ser Thr Phe Thr 
            660                 665                 670


Gly Phe 



<210>  5382
<211>  2631
<212>  DNA
<213>  Homo sapiens

<400>  5382
agacctgaag cggcggaccg agagcccggg tctgagactg agagagcaac ggaatggagg     60

cggggtagag gcggaaacac aacctgcagg gccagagcga ggcgcgagaa ggacggcggc    120

gtgagggggc ggggcgcgca gcgcgagaag gcaggcacga ggggcgagcg cgaggcgggg    180

cacggcgcgt ggcgtgagac ggggcggggc gcgcgtatcg gcgccgcggc cgcgtgacgc    240

gttttcaaat cttcaaccgc cgcagcccac tcgtttgtgc tttgcgcctt cctcctccgc    300

gccttggagc cggatccggc cccggaaacc cgacctgcag acgcggtacc tctactgcgt    360

agaggccgta gctggcggaa ggagagaggc ggccgtcctg tcaacaggcc gggggaagcc    420

gtgctttcgc ggctgcccgg tgcgacactt tctccggacc cagcatgtag gtgccgggcg    480

actgccatga actccggagc catgaggatc cacagtaaag gacatttcca gggtggaatc    540

caagtcaaaa atgaaaaaaa cagaccatct ctgaaatctc tgaaaactga taacaggcca    600

gaaaaatcca aatcgagttg aagaatttct cagcaaagat atcagttatc ttatttcaaa    660

taagaaggaa gctaaatttg cacaaacctt gggtcgaatt tctcctgtac caagtccaga    720

atctgcatat actgcagaaa ccacttcacc tcatcccagc catgatggaa gttcatttaa    780

gtcaccagac acagtgtgtt taagcagagg aaaattatta gttgaaaaag ctatcaagga    840

ccatgatttt attccttcaa atagtatatt atcaaatgcc ttgtcatggg gagtaaaaat    900

tcttcatatt gatgacatta gatactacat tgaacaaaag aaaaaagagt tgtatttact    960

caagaaatca agtacttcag taagagatgg gggcaaaaga gttggtagtg gtgcacaaaa   1020

aacaagaaca ggaagactca aaaagccttt tgtaaaggtg gaagatatga gccaacttta   1080

taggccattt tatcttcagc tgaccaatat gccttttata aattattcta ttcagaagcc   1140

ctgcagtcca tttgatgtag acaagccatc tagtatgcaa aagcaaactc aggttaaact   1200

aagaatccaa acagatggcg ataagtatgg tggaacctca attcaactcc agttgaaaga   1260

gaagaagaaa aaaggatatt gtgaatgttg cttgcagaaa tatgaagatc tagaaactca   1320

ccttctaagt gagcaacaca gaaactttgc acagagtaac cagtatcaag ttgttgatga   1380

tattgtatct aagttagttt ttgactttgt ggaatatgaa aaggacacac ctaaaaagaa   1440

aagaataaaa tacagtgttg gatccctttc tcctgtttct gcaagtgtcc tgaaaaagac   1500

tgaacaaaag gaaaaagtgg aattgcaaca tatttctcag aaagattgcc aggaagatga   1560

tacaacagtg aaggagcaga atttcctgta taaagagacc caggaaactg aaaaaaagct   1620

cctgtttatt tcagagccca tcccccaccc ttcaaatgaa ttgagagggc ttaatgagaa   1680

aatgagtaat aaatgttcca tgttaagtac agctgaagat gacataagac agaattttac   1740

acagctacct ctacataaaa acaaacagga atgcattctt gacatttccg aacacacatt   1800

aagtgaaaat gacttagaag aactaagggt agatcactat aaatgtaaca tacaggcatc   1860

tgtacatgtt tctgatttca gtacagataa tagtggatct caaccaaaac agaagtcaga   1920

tactgtgctt tttccagcaa aggatctcaa ggaaaaggac cttcattcaa tatttactca   1980

tgattctggt ctgataacaa taaacagttc acaagagcac ctaactgttc aggcaaaggc   2040

tccattccat actcctcctg aggaacccaa tgaatgtgac ttcaagaata tggatagttt   2100

accttctggt aaaatacatc gaaaagtgaa aataatatta ggacgaaata gaaaagaaaa   2160

tctggaacca aatgctgaat ttgataaaag aactgaattt attacacaag aagaaaacag   2220

aatttgtagt tcaccggtac agtctttact agacttgttt cagactagtg aagagaaatc   2280

agaatttttg ggtttcacaa gctacacaga aaagagtggt atatgcaatg ttttagatat   2340

ttgggaagag gaaaattcag ataatctgtt aacagcgttt ttctcgtccc cttcaacttc   2400

tacatttact ggcttttaga atttaaaaaa tgcatacttt tcagaagtga taaggatcat   2460

attcttgaaa tttttataaa tatgtatgga aattcttagg atttttttac cagctttgtt   2520

tacagaccca aatgtaaata ttaaaaataa atatttgcaa ttttctacag aattgaatac   2580

ctgttaaaga aaaattacag aataaacttg tgactggtct tgttttacat t            2631


<210>  5383
<211>  450
<212>  PRT
<213>  Homo sapiens

<400>  5383

Met Ser Gln Leu Tyr Arg Pro Phe Tyr Leu Gln Leu Thr Asn Met Pro 
1               5                   10                  15


Phe Ile Asn Tyr Ser Ile Gln Lys Pro Cys Ser Pro Phe Asp Val Asp 
            20                  25                  30


Lys Pro Ser Ser Met Gln Lys Gln Thr Gln Val Lys Leu Arg Ile Gln 
        35                  40                  45


Thr Asp Gly Asp Lys Tyr Gly Gly Thr Ser Ile Gln Leu Gln Leu Lys 
    50                  55                  60


Glu Lys Lys Lys Lys Gly Tyr Cys Glu Cys Cys Leu Gln Lys Tyr Glu 
65                  70                  75                  80


Asp Leu Glu Thr His Leu Leu Ser Glu Gln His Arg Asn Phe Ala Gln 
                85                  90                  95


Ser Asn Gln Tyr Gln Val Val Asp Asp Ile Val Ser Lys Leu Val Phe 
            100                 105                 110


Asp Phe Val Glu Tyr Glu Lys Asp Thr Pro Lys Lys Lys Arg Ile Lys 
        115                 120                 125


Tyr Ser Val Gly Ser Leu Ser Pro Val Ser Ala Ser Val Leu Lys Lys 
    130                 135                 140


Thr Glu Gln Lys Glu Lys Val Glu Leu Gln His Ile Ser Gln Lys Asp 
145                 150                 155                 160


Cys Gln Glu Asp Asp Thr Thr Val Lys Glu Gln Asn Phe Leu Tyr Lys 
                165                 170                 175


Glu Thr Gln Glu Thr Glu Lys Lys Leu Leu Phe Ile Ser Glu Pro Ile 
            180                 185                 190


Pro His Pro Ser Asn Glu Leu Arg Gly Leu Asn Glu Lys Met Ser Asn 
        195                 200                 205


Lys Cys Ser Met Leu Ser Thr Ala Glu Asp Asp Ile Arg Gln Asn Phe 
    210                 215                 220


Thr Gln Leu Pro Leu His Lys Asn Lys Gln Glu Cys Ile Leu Asp Ile 
225                 230                 235                 240


Ser Glu His Thr Leu Ser Glu Asn Asp Leu Glu Glu Leu Arg Val Asp 
                245                 250                 255


His Tyr Lys Cys Asn Ile Gln Ala Ser Val His Val Ser Asp Phe Ser 
            260                 265                 270


Thr Asp Asn Ser Gly Ser Gln Pro Lys Gln Lys Ser Asp Thr Val Leu 
        275                 280                 285


Phe Pro Ala Lys Asp Leu Lys Glu Lys Asp Leu His Ser Ile Phe Thr 
    290                 295                 300


His Asp Ser Gly Leu Ile Thr Ile Asn Ser Ser Gln Glu His Leu Thr 
305                 310                 315                 320


Val Gln Ala Lys Ala Pro Phe His Thr Pro Pro Glu Glu Pro Asn Glu 
                325                 330                 335


Cys Asp Phe Lys Asn Met Asp Ser Leu Pro Ser Gly Lys Ile His Arg 
            340                 345                 350


Lys Val Lys Ile Ile Leu Gly Arg Asn Arg Lys Glu Asn Leu Glu Pro 
        355                 360                 365


Asn Ala Glu Phe Asp Lys Arg Thr Glu Phe Ile Thr Gln Glu Glu Asn 
    370                 375                 380


Arg Ile Cys Ser Ser Pro Val Gln Ser Leu Leu Asp Leu Phe Gln Thr 
385                 390                 395                 400


Ser Glu Glu Lys Ser Glu Phe Leu Gly Phe Thr Ser Tyr Thr Glu Lys 
                405                 410                 415


Ser Gly Ile Cys Asn Val Leu Asp Ile Trp Glu Glu Glu Asn Ser Asp 
            420                 425                 430


Asn Leu Leu Thr Ala Phe Phe Ser Ser Pro Ser Thr Ser Thr Phe Thr 
        435                 440                 445


Gly Phe 
    450


<210>  5384
<211>  915
<212>  DNA
<213>  Homo sapiens

<400>  5384
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agattcagat gtttttgaag tcagaatccc    600

agaagaccat ataccagata cagttgactc atgttgacca agcaagcttc caggttgatg    660

cctttggaac gtcattcatt ctcgatgtcg tgctaaatca tgatttgctg tcctctgaat    720

acatagagag acacattgaa catggaggca agactgtgga agttaaagga ggagagcact    780

gttactacca gggccatatc cgaggaaacc ctgactcatt tgttgcattg tcaacatgcc    840

acggacttca tgggatgttc tatgacggga accacacata tctcattgag ccagaagaaa    900

atgacactac tcaag                                                     915


<210>  5385
<211>  195
<212>  PRT
<213>  Homo sapiens

<400>  5385

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Ile Gln Met Phe Leu Lys Ser Glu Ser Gln Lys Thr Ile Tyr 
                85                  90                  95


Gln Ile Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala 
            100                 105                 110


Phe Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu 
        115                 120                 125


Ser Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val 
    130                 135                 140


Glu Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly 
145                 150                 155                 160


Asn Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly 
                165                 170                 175


Met Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn 
            180                 185                 190


Asp Thr Thr 
        195


<210>  5386
<211>  1026
<212>  DNA
<213>  Homo sapiens

<400>  5386
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatg                                                              1026


<210>  5387
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  5387

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg 
225                 230


<210>  5388
<211>  2681
<212>  DNA
<213>  Homo sapiens

<400>  5388
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgt   1320

acgtaacttc tgtaatgatg tattactttt tttgattcca tgttaaatgc tttattgtga   1380

ctgaaatgta tcctttctgc tacataacac aattaggatt tgacatggca gatggcagat   1440

agatttggaa aaagttttca agtatagatt gcttaaaatt gccatgaaaa tgtaaaagtt   1500

ttaattttga gttattttat tatttaatgt ttaatttttc aagatattta aatagagcat   1560

ttactgagta aaaatactgc taatactcat atatagtatt cttaactaca gataaattat   1620

attctttaaa gttactgtct tttaaatgtt aatgttttct ctgtttttgg ttctaagatg   1680

agagcttagt atttctggaa tttattttta attttttctc actcttatgt tctttttttg   1740

atagcatgca tatttgacgt aatagcaaat tatatatagt agaattttaa aaatctatca   1800

tctaaagtca gagctgttga agaaagttat aaaaggaaga aaagatgtat tttggggtaa   1860

ctttatatat aattccaaat ttagagaaaa gttgcaagaa tactacaagg aaattgcata   1920

tgccctctat tcagattcat caattattca cattttcccc atttgtttca taattttctt   1980

ccattctccc tcccttcctt ccattcatcc atccttcagt tttttttttg tttttttttg   2040

ttttttttcc tgaacctctt gaaagtaagt tgaagacact tactggggat ttattattaa   2100

atagtatata ttctctaaga gtaaaaagac attctcttat ataaccacag taaattatta   2160

aaaccagaaa atttaacaca aacataatac ttttatgtaa cccatggtct atattcaaat   2220

ttcaccaatt acctcaataa tgtcttttaa agctaatttt ccccatccaa atccaatcca   2280

ggatcacaca ttgcatttaa tcatcatgtc tctttagtct cctttaatct gaaagatttc   2340

ctcagctttc ctttgtctat tttgagttta atacttttga agagtatagg ccaattattt   2400

tattgactgt tcctcattat gggaatgcct gatgttaaga tatgtatttt tggcagaaat   2460

accagagaag tgattttgtg tctgtctcag agtacatcat atcaaccaat tattttttaa   2520

tagatatact tcaatttaag atatttatta atcttgcaag aaaacatccc tcataaacct   2580

ttttctttgg ttacatgtat aaacaatttt cacattcttc ccttgcaatg tgaatatatt   2640

gtatagaaat cttatgtata gagaaaataa atgtagtaaa c                       2681


<210>  5389
<211>  342
<212>  PRT
<213>  Homo sapiens

<400>  5389

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Tyr Val Thr Ser Val 
                325                 330                 335


Met Met Tyr Tyr Phe Phe 
            340


<210>  5390
<211>  2991
<212>  DNA
<213>  Homo sapiens

<400>  5390
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagagacag ttaccccagg   2640

gagattatgt aaaaaagcct ggagatggtg actcttttta tagcgacatt cctcccggag   2700

tcagcacaaa ctcagcatct agttctaaga agaggtcaaa tgggctctct cattcttgga   2760

gtgaaaggat tccagacaca aaacatattt cagacatctg tgaaaatggg cgacctcgaa   2820

gtaactcttg gcaaggtaac ctgggaggca acaaaaagaa aatcagaggc aaaagattta   2880

gacctcggtc taattcaact gagtaagtct gaacctctaa tggaaaaagg cactccaagg   2940

tcctgtgcaa atagtgtcaa aagtaaatta agcagatagt caaagaactg t            2991


<210>  5391
<211>  859
<212>  PRT
<213>  Homo sapiens

<400>  5391

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Gln 
        755                 760                 765


Leu Pro Gln Gly Asp Tyr Val Lys Lys Pro Gly Asp Gly Asp Ser Phe 
    770                 775                 780


Tyr Ser Asp Ile Pro Pro Gly Val Ser Thr Asn Ser Ala Ser Ser Ser 
785                 790                 795                 800


Lys Lys Arg Ser Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro 
                805                 810                 815


Asp Thr Lys His Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser 
            820                 825                 830


Asn Ser Trp Gln Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly 
        835                 840                 845


Lys Arg Phe Arg Pro Arg Ser Asn Ser Thr Glu 
    850                 855


<210>  5392
<211>  2883
<212>  DNA
<213>  Homo sapiens

<400>  5392
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagaggtca aatgggctct   2640

ctcattcttg gagtgaaagg attccagaca caaaacatat ttcagacatc tgtgaaaatg   2700

ggcgacctcg aagtaactct tggcaaggta acctgggagg caacaaaaag aaaatcagag   2760

gcaaaagatt tagacctcgg tctaattcaa ctgagtaagt ctgaacctct aatggaaaaa   2820

ggcactccaa ggtcctgtgc aaatagtgtc aaaagtaaat taagcagata gtcaaagaac   2880

tgt                                                                 2883


<210>  5393
<211>  823
<212>  PRT
<213>  Homo sapiens

<400>  5393

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Ser 
        755                 760                 765


Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro Asp Thr Lys His 
    770                 775                 780


Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser Asn Ser Trp Gln 
785                 790                 795                 800


Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly Lys Arg Phe Arg 
                805                 810                 815


Pro Arg Ser Asn Ser Thr Glu 
            820


<210>  5394
<211>  3580
<212>  DNA
<213>  Homo sapiens

<400>  5394
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagaggtca aatgggctct   2640

ctcattcttg gagtgaaagg attccagaca caaaacatat ttcagacatc tgtgaaaatg   2700

ggcgacctcg aagtaactct tggcaaggta acctgggagg caacaaaaag aaaatcagag   2760

gcaaaagatt tagacctcgg tctaattcaa ctgagacttt atctcctgcc aagtctcctt   2820

cttcatcaac tgggtctatt gcctccagca gaaaataccc ttacccaatg cctccacttc   2880

ctgatgagga caagaaagtg aaccgacaaa gtgccaggct atgggagaca tccatttaag   2940

atcaactgtt tacatgtgat acatcgaaaa ctgtttactt caacttttat agaaacccag   3000

gctcatggaa tcactgcaaa tctatctgct cttcagacaa tacgaagacc ctctgagatg   3060

ctacagagga gaggaagcgg agtttcacat ctggttacca ttttcttttt gtcattggct   3120

taggatttaa ctaaccatga aaagaactac tgaaatatta cactataaca tggaacaata   3180

aaggtactgg tatgttaatg gataatccgc atgacagata atatgtagaa atattcataa   3240

agttaactca catgacccaa atgtagcaag tttcctaagg tacaatagtg gattcagaac   3300

ttgacgttct gaggcacatc ctcactgtaa acagtaatgc tatatgcatg aagcttctgt   3360

ttattgtttt ccatatttaa ggaaacaaca tcccataata gaaatgagca tgcagggcta   3420

aggcatatag gatttttctg caggacttta aagctttgaa aggccaatat cccataggct   3480

aactttaaac atgtattttt atttttgttt tgttttttac ttttcatatt tatattagca   3540

tacaaggaca attgtatata tgtaacattt ttaaaatttt                         3580


<210>  5395
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  5395

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Ser 
        755                 760                 765


Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro Asp Thr Lys His 
    770                 775                 780


Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser Asn Ser Trp Gln 
785                 790                 795                 800


Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly Lys Arg Phe Arg 
                805                 810                 815


Pro Arg Ser Asn Ser Thr Glu Thr Leu Ser Pro Ala Lys Ser Pro Ser 
            820                 825                 830


Ser Ser Thr Gly Ser Ile Ala Ser Ser Arg Lys Tyr Pro Tyr Pro Met 
        835                 840                 845


Pro Pro Leu Pro Asp Glu Asp Lys Lys Val Asn Arg Gln Ser Ala Arg 
    850                 855                 860


Leu Trp Glu Thr Ser Ile 
865                 870


<210>  5396
<211>  3688
<212>  DNA
<213>  Homo sapiens

<400>  5396
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagagacag ttaccccagg   2640

gagattatgt aaaaaagcct ggagatggtg actcttttta tagcgacatt cctcccggag   2700

tcagcacaaa ctcagcatct agttctaaga agaggtcaaa tgggctctct cattcttgga   2760

gtgaaaggat tccagacaca aaacatattt cagacatctg tgaaaatggg cgacctcgaa   2820

gtaactcttg gcaaggtaac ctgggaggca acaaaaagaa aatcagaggc aaaagattta   2880

gacctcggtc taattcaact gagactttat ctcctgccaa gtctccttct tcatcaactg   2940

ggtctattgc ctccagcaga aaataccctt acccaatgcc tccacttcct gatgaggaca   3000

agaaagtgaa ccgacaaagt gccaggctat gggagacatc catttaagat caactgttta   3060

catgtgatac atcgaaaact gtttacttca acttttatag aaacccaggc tcatggaatc   3120

actgcaaatc tatctgctct tcagacaata cgaagaccct ctgagatgct acagaggaga   3180

ggaagcggag tttcacatct ggttaccatt ttctttttgt cattggctta ggatttaact   3240

aaccatgaaa agaactactg aaatattaca ctataacatg gaacaataaa ggtactggta   3300

tgttaatgga taatccgcat gacagataat atgtagaaat attcataaag ttaactcaca   3360

tgacccaaat gtagcaagtt tcctaaggta caatagtgga ttcagaactt gacgttctga   3420

ggcacatcct cactgtaaac agtaatgcta tatgcatgaa gcttctgttt attgttttcc   3480

atatttaagg aaacaacatc ccataataga aatgagcatg cagggctaag gcatatagga   3540

tttttctgca ggactttaaa gctttgaaag gccaatatcc cataggctaa ctttaaacat   3600

gtatttttat ttttgttttg ttttttactt ttcatattta tattagcata caaggacaat   3660

tgtatatatg taacattttt aaaatttt                                      3688


<210>  5397
<211>  906
<212>  PRT
<213>  Homo sapiens

<400>  5397

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Gln 
        755                 760                 765


Leu Pro Gln Gly Asp Tyr Val Lys Lys Pro Gly Asp Gly Asp Ser Phe 
    770                 775                 780


Tyr Ser Asp Ile Pro Pro Gly Val Ser Thr Asn Ser Ala Ser Ser Ser 
785                 790                 795                 800


Lys Lys Arg Ser Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro 
                805                 810                 815


Asp Thr Lys His Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser 
            820                 825                 830


Asn Ser Trp Gln Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly 
        835                 840                 845


Lys Arg Phe Arg Pro Arg Ser Asn Ser Thr Glu Thr Leu Ser Pro Ala 
    850                 855                 860


Lys Ser Pro Ser Ser Ser Thr Gly Ser Ile Ala Ser Ser Arg Lys Tyr 
865                 870                 875                 880


Pro Tyr Pro Met Pro Pro Leu Pro Asp Glu Asp Lys Lys Val Asn Arg 
                885                 890                 895


Gln Ser Ala Arg Leu Trp Glu Thr Ser Ile 
            900                 905


<210>  5398
<211>  9337
<212>  DNA
<213>  Homo sapiens

<400>  5398
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagaggtca aatgggctct   2640

ctcattcttg gagtgaaagg attccagaca caaaacatat ttcagacatc tgtgaaaatg   2700

ggcgacctcg aagtaactct tggcaaggta acctgggagg caacaaaaag aaaatcagag   2760

gcaaaagatt tagacctcgg tctaattcaa ctgagacttt atctcctgcc aagtctcctt   2820

cttcatcaac tgggtctatt gcctccagca gaaaataccc ttacccaatg cctccacttc   2880

ctgatgagga caagaaagtg aaccgacaaa gtgccaggct atgggagaca tccatttaag   2940

atcaactgtt tacatgtgat acatcgaaaa ctgtttactt caacttttat agaaacccag   3000

gctcatggaa tcactgcaaa tctatctgct cttcagacaa tacgaagacc ctctgagatg   3060

ctacagagga gaggaagcgg agtttcacat ctggttacca ttttcttttt gtcattggct   3120

taggatttaa ctaaccatga aaagaactac tgaaatatta cactataaca tggaacaata   3180

aaggtactgg tatgttaatg gataatccgc atgacagata atatgtagaa atattcataa   3240

agttaactca catgacccaa atgtagcaag tttcctaagg tacaatagtg gattcagaac   3300

ttgacgttct gaggcacatc ctcactgtaa acagtaatgc tatatgcatg aagcttctgt   3360

ttattgtttt ccatatttaa ggaaacaaca tcccataata gaaatgagca tgcagggcta   3420

aggcatatag gatttttctg caggacttta aagctttgaa aggccaatat cccataggct   3480

aactttaaac atgtattttt atttttgttt tgttttttac ttttcatatt tatattagca   3540

tacaaggaca attgtatata tgtaacattt ttaaaatttt aaaaaaatgc agctgttaca   3600

cacaagtgta ttttgccaaa tgcctaaaaa ttccgtcaca atcacatcat cgtcatccat   3660

ccagtgatct tcaaagacta taagcaggta atgtaaatat agtggtcaat gctgtaaatg   3720

tgtctctcca taattcgtat ttgtccaaaa catgtgatat ccctttaacc tgtgcacagt   3780

ctggaggcag ttttattgag tgagtagttg agtgagagaa caaaatgccc agcaaaactt   3840

ctggcctcca cagtttgctg atgcaggagc ccactctgct gccgatgggc tgctccctgg   3900

aaatcatcta tcccatccgt ccatcccatc tcatcccagt gagccagccc ctcagcagtg   3960

tgtgctgctg agattaagca agtgcaccaa agacacatga gacaacgtac tgccagtgag   4020

ctggtagctt ctggtttgcc aatactctaa ccctttgtgg cctgaagttt tgttccttgg   4080

caaaactttg tagtcaccct tatctgtgaa atgaatgact tgttttaaca aaaacaactt   4140

tgacactgtt gattaagaat atttgtcatc actgggatgt gaatcccaac aagtcattct   4200

gcactgactc tgaagcaaga tgacggaaga ttctactgtt tgagttgagc agcttcaacc   4260

attcataaag ggttaagtta gatctaaacc acagagatgc agcatctgcg aagttacact   4320

aacagctggt gggggaaaga atctgatgct ttgaaacata tatttttaat ccataggaaa   4380

ataagattct attttaaaag acccttcttt aaaaccaaag tttgatagct gttataatgg   4440

cagatctgtc attccaaaag aaagctagct accctagtga ggctggagat tgatgggctc   4500

aatcacatgg tctgctctga agtatacttc tgatttcctc atttgctgtg tgttcttaag   4560

aggaatggaa tctgcagaca ggttttcaga tatactctct taaatttgat cctctcccat   4620

agtatccatg gacaaaatcc atatcatctt catatgtaat caatttgatt acatatcatg   4680

cccaaactga agggccgagt tagaaggcag cattttatac tgtgtgttta tgtcttctgt   4740

aatggacctc tcttttgaaa gtctttgaaa tgtttggaaa gcaatttaat gatccaaaat   4800

tacataatgt aaaacagcat ttttcatgac aggaagggat gtgattgttg atatgaccat   4860

aaagcgatcc atcaggccaa ggtttgggtg agtgttgggc agtgttgcca catagctcaa   4920

gccaagaaca gaagggcaga cagattgaaa gatgtagcaa ataaagtgac tttttaccaa   4980

gatcactgta acgtgcactg aatgtttcct ggtactgagt gtacaaaagg ctaatgctat   5040

aaggtttatt ttgactataa aagagtttat agatttgaat ataaggtgcc tcatgtaaat   5100

atgcttccta gttacaggta cacaaactct aatttgaaag aatccacaaa tggctagctg   5160

agaagttaac agatctctat cattcgtctg tgtgtctttc ttccctcacc tatttttaca   5220

tgaaattatt atttcaaatg aaaatcatga tcatgtgcct tttgggagac atggtttctc   5280

tagaggtata tagtttgtaa ttacccgcct tggtaataac cttcctgtgg aactgactaa   5340

aaatttttgt tttatttgta gagattatga tttgaggtat acagtaactt taatgttcta   5400

ttcttggaat ctactctatc tcccatgttt aaacattctt agagccattt gtgggattca   5460

ttgacaaatt tatagtctca agggagagtt tcaagaagta tctatatgta tactcatggt   5520

tggggttcta gaggcattac atctaaatat ttatgacttt tcatccaccg aggtaggtag   5580

cattaaatat acaagcacag cattatttct ctttaaatat ctattttgga gagaaacttt   5640

gaggccgtat cacagtttat atcatgcaac taatatttat atttcccaat ccactacaaa   5700

atcattgcta agcagaagag agcagttatt tggcctttat gttccattgt atgccttttt   5760

cccctcttcc agttttatgc attgataaga ctacagattg gcaccctgct gcctgagaag   5820

ttccatttat ccatagtcat tgcagtgcag taaaccctga tttaaaggaa catttaagtc   5880

tctccagtaa gtgtgaacag gaaggcatgg gatagaagag agtccttatg gagtggactg   5940

gccacatgaa ctgtcctcca gccactcttt atttagatgg gaagtggcat ggtcctctga   6000

acgctgcagg ctggaaatga tccccagggc acatgcaatc tgtggaaagg aatacatcgg   6060

acagtgcaac atggtgaggg ctttcaattt gctgtggttg ctgtattttt aacaagacac   6120

ccggagcttc gattaggaat aacctatcat tagagttgtt cctttaaaaa atgttgatga   6180

ataaagcaaa tgtgggttta aaatgccaac ttatttttca ctttgatatt ggtgctttat   6240

taagtgatac catagtttct ctctcttttc cctgttactt taaaaagaat tttaaaattg   6300

tgtttgtata taaggtcagt ctggcataga atttctgaaa gtaacattaa taggatttct   6360

aaagaagttg tcagaaagac aaaattggat attctctgca ctttcagaga aggactattt   6420

atgtttgaat ttcataacag gcttacattt cttttctatt gattcccttg catatctaca   6480

taatttaatc ctgtctattg tcccagatct cttgtggcta ctttacctgt tacctttttt   6540

gggattttgt tctttatgtt ttacagttac cttcggacca gaagatatat ggtattttta   6600

ttcacttttt tcagtgtttt aaaataaggt ttgttcattt attcatttta tccattcatt   6660

tcctattgtc gtatagttct aaccatatat atagtacttt aaatattttc ttatgttatt   6720

atttaacaca ataataaatt cttatctaaa gaaaagatta ttttacttta ttttacttaa   6780

aggaaagaga atttattggc aggatattga gtagcttgta gagtatatgg aaggggagag   6840

ccaagttagg aactggcagg agcgaggagg gacaagacag ctgcctgcac agtctgatag   6900

gacacatctg gctgctgcca ctggatgccc acatgggcag cgtgttgtaa atatcaccct   6960

accagttggt aagttggcat gaattttcca tgaaacactt gactgccatt tgcagcatca   7020

tatctacttt ttatgcacct aattatattt ttcctttcac ttttatgttt ttttctaaaa   7080

ctgccaccta aatacctttc cactccgtta aatgtatgga gtcaagataa atttctcatt   7140

cttgctctac agtttaagat gtataagaag taaacacttc cgtggaatag ggcttaattt   7200

ggggctcaaa tgttttgttt tcctcctgag atgtttttga atggataaga ctactctggt   7260

tttggatgca gcaacttttc tcctggcatg gaagaactaa ggactttgat aaacagtttc   7320

ccattgatag tataatataa tgaggggccc agtctgctct tgtgaaaatt ggctgagcgg   7380

cagcagccca tcccagctgt gtgtgagtag ccccgctgtt aaaagtacac ctgctgggaa   7440

ttgttggcac atgctcatag catatgctct gtgggggagg tgcttttaat tccaagagga   7500

gcttttctcc cacatctgcg gatgcagaac aaagatgcag caggacttta gaaaacagga   7560

gtgtttctac tgacatttta ttcattgctt tgttagtccc gcaaatggag caacttctgg   7620

ttgtttgtaa gcagaaaaac aaaacattca aaaccaaaaa cctaattagt acttttgtcc   7680

tttatatccc taggatgctc tagggagtag aggtggcagg catctttatc ttcacccact   7740

ggcacattag cagcttatgc aacttaggaa gtcactggga gatgagtcct aaaagcctga   7800

atttcaggat ggggaggaga taagaagcag agaactttgg gagaccatgg ggcatttagt   7860

cctggcatag acacagaatg gatattcaca ggaagattcc tgaggccaga tatgcaggag   7920

agcacacatt gtcacaaggg gtgtggtggg aagagaggtg ctggatgcct aagacagact   7980

tctgtgcttg gcagattgac tgagtgttga ctctgaatac tttgtggtcc agtccataat   8040

aggccagtca ctcctgcctg atgcatccct gttgcactgt tcataaaacc tgtatcatat   8100

ggggaagctt caaggctggc aggcttttca tcaagtaatc atcattccat gttcctacgt   8160

atccttgaaa tcaaaaccag gcaatatgtg tgtttttggt tttgttttac aaaaaggcat   8220

acaatgagac gaattcttaa gataatgcac atacagaatc atcaataaag tttcaaagag   8280

tttatgaaga aaaggtattt tcctttcttg taaaaaatgt tatatatata taatattctg   8340

atctgcattc accttagggc ttagcctctt attttatgaa ttttcaggct gtgatttgtg   8400

ttggatggct aagctctaaa ataatgcaaa tagccccaat ctttaaatat agcggtgcta   8460

agttgaacaa gtaacacaat acagaaaatg ctgatatgaa tacttagtaa taatacaaaa   8520

gttcctgcta aattatatat gtgtatcact gcctgactag aaaccccact tttcttttct   8580

aatccagcac aaaatcaaac tctgattcta caaccagtct ttttaaaggg caaaaatgac   8640

tcaacacctt tgttttgtat ggaaaacttt tttttttaca ctaactgcaa aactgcttta   8700

aaaaaaggct tattcaggat agataagcat gtactccttt tttaacttgc tggaagactt   8760

gcccctccaa actagcaccc ccaaaagaca acttctttca gaaacggggt gttttaccta   8820

aacatagtag cttacatgtt agccagcagt aggtcggcac tagtgttttc cacggttatc   8880

acctttgaca ggtgatgtgc atctatagat agtggaagcc accccatgag gaggtgttaa   8940

tagcagcatg gtttcacttt tggtaatcag gtaatcatgt gtatatactt agattcgcat   9000

tattttaaca tttctctgct actctgcact tcaggttcgt taagctattt taataattac   9060

tggggttatg gcaaacacca atggaaatgt atatggcaac tgctttcctg agcaagtgtg   9120

atttgtttta tggctgttca agttataaaa ttgttcttac attgtaggta aacaaaatct   9180

tgatgttttt aaaggtcact gtaacttaag gttcaaattt ctggcacagt tttattagta   9240

ttcacttcgg aagctaataa gataccatgg ttttctatgt tactcccatt gtaacattag   9300

taaagtgact ttcaataaaa gatttatgtt attttga                            9337


<210>  5399
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  5399

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Ser 
        755                 760                 765


Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro Asp Thr Lys His 
    770                 775                 780


Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser Asn Ser Trp Gln 
785                 790                 795                 800


Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly Lys Arg Phe Arg 
                805                 810                 815


Pro Arg Ser Asn Ser Thr Glu Thr Leu Ser Pro Ala Lys Ser Pro Ser 
            820                 825                 830


Ser Ser Thr Gly Ser Ile Ala Ser Ser Arg Lys Tyr Pro Tyr Pro Met 
        835                 840                 845


Pro Pro Leu Pro Asp Glu Asp Lys Lys Val Asn Arg Gln Ser Ala Arg 
    850                 855                 860


Leu Trp Glu Thr Ser Ile 
865                 870


<210>  5400
<211>  9424
<212>  DNA
<213>  Homo sapiens

<400>  5400
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagaggtca aatgggctct   2640

ctcattcttg gagtgaaagg attccagaca caaaacatat ttcagacatc tgtgaaaatg   2700

ggcgacctcg aagtaactct tggcaaggta acctgggagg caacaaaaag aaaatcagag   2760

gcaaaagatt tagacctcgg tctaattcaa ctgagtattt aaacccatgg ttcaaaagag   2820

actataatgt agctaagtgg gtagaagatg tgaataaaaa cactgaagga ccatacttta   2880

ggactttatc tcctgccaag tctccttctt catcaactgg gtctattgcc tccagcagaa   2940

aataccctta cccaatgcct ccacttcctg atgaggacaa gaaagtgaac cgacaaagtg   3000

ccaggctatg ggagacatcc atttaagatc aactgtttac atgtgataca tcgaaaactg   3060

tttacttcaa cttttataga aacccaggct catggaatca ctgcaaatct atctgctctt   3120

cagacaatac gaagaccctc tgagatgcta cagaggagag gaagcggagt ttcacatctg   3180

gttaccattt tctttttgtc attggcttag gatttaacta accatgaaaa gaactactga   3240

aatattacac tataacatgg aacaataaag gtactggtat gttaatggat aatccgcatg   3300

acagataata tgtagaaata ttcataaagt taactcacat gacccaaatg tagcaagttt   3360

cctaaggtac aatagtggat tcagaacttg acgttctgag gcacatcctc actgtaaaca   3420

gtaatgctat atgcatgaag cttctgttta ttgttttcca tatttaagga aacaacatcc   3480

cataatagaa atgagcatgc agggctaagg catataggat ttttctgcag gactttaaag   3540

ctttgaaagg ccaatatccc ataggctaac tttaaacatg tatttttatt tttgttttgt   3600

tttttacttt tcatatttat attagcatac aaggacaatt gtatatatgt aacattttta   3660

aaattttaaa aaaatgcagc tgttacacac aagtgtattt tgccaaatgc ctaaaaattc   3720

cgtcacaatc acatcatcgt catccatcca gtgatcttca aagactataa gcaggtaatg   3780

taaatatagt ggtcaatgct gtaaatgtgt ctctccataa ttcgtatttg tccaaaacat   3840

gtgatatccc tttaacctgt gcacagtctg gaggcagttt tattgagtga gtagttgagt   3900

gagagaacaa aatgcccagc aaaacttctg gcctccacag tttgctgatg caggagccca   3960

ctctgctgcc gatgggctgc tccctggaaa tcatctatcc catccgtcca tcccatctca   4020

tcccagtgag ccagcccctc agcagtgtgt gctgctgaga ttaagcaagt gcaccaaaga   4080

cacatgagac aacgtactgc cagtgagctg gtagcttctg gtttgccaat actctaaccc   4140

tttgtggcct gaagttttgt tccttggcaa aactttgtag tcacccttat ctgtgaaatg   4200

aatgacttgt tttaacaaaa acaactttga cactgttgat taagaatatt tgtcatcact   4260

gggatgtgaa tcccaacaag tcattctgca ctgactctga agcaagatga cggaagattc   4320

tactgtttga gttgagcagc ttcaaccatt cataaagggt taagttagat ctaaaccaca   4380

gagatgcagc atctgcgaag ttacactaac agctggtggg ggaaagaatc tgatgctttg   4440

aaacatatat ttttaatcca taggaaaata agattctatt ttaaaagacc cttctttaaa   4500

accaaagttt gatagctgtt ataatggcag atctgtcatt ccaaaagaaa gctagctacc   4560

ctagtgaggc tggagattga tgggctcaat cacatggtct gctctgaagt atacttctga   4620

tttcctcatt tgctgtgtgt tcttaagagg aatggaatct gcagacaggt tttcagatat   4680

actctcttaa atttgatcct ctcccatagt atccatggac aaaatccata tcatcttcat   4740

atgtaatcaa tttgattaca tatcatgccc aaactgaagg gccgagttag aaggcagcat   4800

tttatactgt gtgtttatgt cttctgtaat ggacctctct tttgaaagtc tttgaaatgt   4860

ttggaaagca atttaatgat ccaaaattac ataatgtaaa acagcatttt tcatgacagg   4920

aagggatgtg attgttgata tgaccataaa gcgatccatc aggccaaggt ttgggtgagt   4980

gttgggcagt gttgccacat agctcaagcc aagaacagaa gggcagacag attgaaagat   5040

gtagcaaata aagtgacttt ttaccaagat cactgtaacg tgcactgaat gtttcctggt   5100

actgagtgta caaaaggcta atgctataag gtttattttg actataaaag agtttataga   5160

tttgaatata aggtgcctca tgtaaatatg cttcctagtt acaggtacac aaactctaat   5220

ttgaaagaat ccacaaatgg ctagctgaga agttaacaga tctctatcat tcgtctgtgt   5280

gtctttcttc cctcacctat ttttacatga aattattatt tcaaatgaaa atcatgatca   5340

tgtgcctttt gggagacatg gtttctctag aggtatatag tttgtaatta cccgccttgg   5400

taataacctt cctgtggaac tgactaaaaa tttttgtttt atttgtagag attatgattt   5460

gaggtataca gtaactttaa tgttctattc ttggaatcta ctctatctcc catgtttaaa   5520

cattcttaga gccatttgtg ggattcattg acaaatttat agtctcaagg gagagtttca   5580

agaagtatct atatgtatac tcatggttgg ggttctagag gcattacatc taaatattta   5640

tgacttttca tccaccgagg taggtagcat taaatataca agcacagcat tatttctctt   5700

taaatatcta ttttggagag aaactttgag gccgtatcac agtttatatc atgcaactaa   5760

tatttatatt tcccaatcca ctacaaaatc attgctaagc agaagagagc agttatttgg   5820

cctttatgtt ccattgtatg cctttttccc ctcttccagt tttatgcatt gataagacta   5880

cagattggca ccctgctgcc tgagaagttc catttatcca tagtcattgc agtgcagtaa   5940

accctgattt aaaggaacat ttaagtctct ccagtaagtg tgaacaggaa ggcatgggat   6000

agaagagagt ccttatggag tggactggcc acatgaactg tcctccagcc actctttatt   6060

tagatgggaa gtggcatggt cctctgaacg ctgcaggctg gaaatgatcc ccagggcaca   6120

tgcaatctgt ggaaaggaat acatcggaca gtgcaacatg gtgagggctt tcaatttgct   6180

gtggttgctg tatttttaac aagacacccg gagcttcgat taggaataac ctatcattag   6240

agttgttcct ttaaaaaatg ttgatgaata aagcaaatgt gggtttaaaa tgccaactta   6300

tttttcactt tgatattggt gctttattaa gtgataccat agtttctctc tcttttccct   6360

gttactttaa aaagaatttt aaaattgtgt ttgtatataa ggtcagtctg gcatagaatt   6420

tctgaaagta acattaatag gatttctaaa gaagttgtca gaaagacaaa attggatatt   6480

ctctgcactt tcagagaagg actatttatg tttgaatttc ataacaggct tacatttctt   6540

ttctattgat tcccttgcat atctacataa tttaatcctg tctattgtcc cagatctctt   6600

gtggctactt tacctgttac cttttttggg attttgttct ttatgtttta cagttacctt   6660

cggaccagaa gatatatggt atttttattc acttttttca gtgttttaaa ataaggtttg   6720

ttcatttatt cattttatcc attcatttcc tattgtcgta tagttctaac catatatata   6780

gtactttaaa tattttctta tgttattatt taacacaata ataaattctt atctaaagaa   6840

aagattattt tactttattt tacttaaagg aaagagaatt tattggcagg atattgagta   6900

gcttgtagag tatatggaag gggagagcca agttaggaac tggcaggagc gaggagggac   6960

aagacagctg cctgcacagt ctgataggac acatctggct gctgccactg gatgcccaca   7020

tgggcagcgt gttgtaaata tcaccctacc agttggtaag ttggcatgaa ttttccatga   7080

aacacttgac tgccatttgc agcatcatat ctacttttta tgcacctaat tatatttttc   7140

ctttcacttt tatgtttttt tctaaaactg ccacctaaat acctttccac tccgttaaat   7200

gtatggagtc aagataaatt tctcattctt gctctacagt ttaagatgta taagaagtaa   7260

acacttccgt ggaatagggc ttaatttggg gctcaaatgt tttgttttcc tcctgagatg   7320

tttttgaatg gataagacta ctctggtttt ggatgcagca acttttctcc tggcatggaa   7380

gaactaagga ctttgataaa cagtttccca ttgatagtat aatataatga ggggcccagt   7440

ctgctcttgt gaaaattggc tgagcggcag cagcccatcc cagctgtgtg tgagtagccc   7500

cgctgttaaa agtacacctg ctgggaattg ttggcacatg ctcatagcat atgctctgtg   7560

ggggaggtgc ttttaattcc aagaggagct tttctcccac atctgcggat gcagaacaaa   7620

gatgcagcag gactttagaa aacaggagtg tttctactga cattttattc attgctttgt   7680

tagtcccgca aatggagcaa cttctggttg tttgtaagca gaaaaacaaa acattcaaaa   7740

ccaaaaacct aattagtact tttgtccttt atatccctag gatgctctag ggagtagagg   7800

tggcaggcat ctttatcttc acccactggc acattagcag cttatgcaac ttaggaagtc   7860

actgggagat gagtcctaaa agcctgaatt tcaggatggg gaggagataa gaagcagaga   7920

actttgggag accatggggc atttagtcct ggcatagaca cagaatggat attcacagga   7980

agattcctga ggccagatat gcaggagagc acacattgtc acaaggggtg tggtgggaag   8040

agaggtgctg gatgcctaag acagacttct gtgcttggca gattgactga gtgttgactc   8100

tgaatacttt gtggtccagt ccataatagg ccagtcactc ctgcctgatg catccctgtt   8160

gcactgttca taaaacctgt atcatatggg gaagcttcaa ggctggcagg cttttcatca   8220

agtaatcatc attccatgtt cctacgtatc cttgaaatca aaaccaggca atatgtgtgt   8280

ttttggtttt gttttacaaa aaggcataca atgagacgaa ttcttaagat aatgcacata   8340

cagaatcatc aataaagttt caaagagttt atgaagaaaa ggtattttcc tttcttgtaa   8400

aaaatgttat atatatataa tattctgatc tgcattcacc ttagggctta gcctcttatt   8460

ttatgaattt tcaggctgtg atttgtgttg gatggctaag ctctaaaata atgcaaatag   8520

ccccaatctt taaatatagc ggtgctaagt tgaacaagta acacaataca gaaaatgctg   8580

atatgaatac ttagtaataa tacaaaagtt cctgctaaat tatatatgtg tatcactgcc   8640

tgactagaaa ccccactttt cttttctaat ccagcacaaa atcaaactct gattctacaa   8700

ccagtctttt taaagggcaa aaatgactca acacctttgt tttgtatgga aaactttttt   8760

ttttacacta actgcaaaac tgctttaaaa aaaggcttat tcaggataga taagcatgta   8820

ctcctttttt aacttgctgg aagacttgcc cctccaaact agcaccccca aaagacaact   8880

tctttcagaa acggggtgtt ttacctaaac atagtagctt acatgttagc cagcagtagg   8940

tcggcactag tgttttccac ggttatcacc tttgacaggt gatgtgcatc tatagatagt   9000

ggaagccacc ccatgaggag gtgttaatag cagcatggtt tcacttttgg taatcaggta   9060

atcatgtgta tatacttaga ttcgcattat tttaacattt ctctgctact ctgcacttca   9120

ggttcgttaa gctattttaa taattactgg ggttatggca aacaccaatg gaaatgtata   9180

tggcaactgc tttcctgagc aagtgtgatt tgttttatgg ctgttcaagt tataaaattg   9240

ttcttacatt gtaggtaaac aaaatcttga tgtttttaaa ggtcactgta acttaaggtt   9300

caaatttctg gcacagtttt attagtattc acttcggaag ctaataagat accatggttt   9360

tctatgttac tcccattgta acattagtaa agtgactttc aataaaagat ttatgttatt   9420

ttga                                                                9424


<210>  5401
<211>  899
<212>  PRT
<213>  Homo sapiens

<400>  5401

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Ser 
        755                 760                 765


Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro Asp Thr Lys His 
    770                 775                 780


Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser Asn Ser Trp Gln 
785                 790                 795                 800


Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly Lys Arg Phe Arg 
                805                 810                 815


Pro Arg Ser Asn Ser Thr Glu Tyr Leu Asn Pro Trp Phe Lys Arg Asp 
            820                 825                 830


Tyr Asn Val Ala Lys Trp Val Glu Asp Val Asn Lys Asn Thr Glu Gly 
        835                 840                 845


Pro Tyr Phe Arg Thr Leu Ser Pro Ala Lys Ser Pro Ser Ser Ser Thr 
    850                 855                 860


Gly Ser Ile Ala Ser Ser Arg Lys Tyr Pro Tyr Pro Met Pro Pro Leu 
865                 870                 875                 880


Pro Asp Glu Asp Lys Lys Val Asn Arg Gln Ser Ala Arg Leu Trp Glu 
                885                 890                 895


Thr Ser Ile 



<210>  5402
<211>  9445
<212>  DNA
<213>  Homo sapiens

<400>  5402
caccgggcgc tcgctccctg ccgagctctt gtcgcccgcc cgagcctttg ccaggggatg     60

aggtgggagg cgctagaaac cacttagcta cagccaaccg cccaatgcag cactcgctcg    120

ctccccccgc cagcggaagc gtccgcgaag cacaatgcag cactgagccg cggtggaggt    180

tgcagcgcca cggccgccgc agcaccggcc ggggctgggt ggaggtggcc gcggggaccc    240

cgggggcgcg gagcgaggga aacggactcg gcggcgccgg catgaggagc tgagcgtctc    300

gggcgaggcg ggctgacggc agcaccatgc aggcggcagt ggctgtgtcc gtgcccttct    360

tgctgctctg tgtcctgggg acctgccctc cggcgcgctg cggccaggca ggagacgcct    420

cattgatgga gctagagaag aggaaggaaa accgcttcgt ggagcgccag agcatcgtgc    480

cactgcgcct catctaccgc tcgggcggcg aagacgaaag tcggcacgac gcgctcgaca    540

cgcgggtgcg gggcgacctc ggtggcccgc agttgactca tgttgaccaa gcaagcttcc    600

aggttgatgc ctttggaacg tcattcattc tcgatgtcgt gctaaatcat gatttgctgt    660

cctctgaata catagagaga cacattgaac atggaggcaa gactgtggaa gttaaaggag    720

gagagcactg ttactaccag ggccatatcc gaggaaaccc tgactcattt gttgcattgt    780

caacatgcca cggacttcat gggatgttct atgacgggaa ccacacatat ctcattgagc    840

cagaagaaaa tgacactact caagaggatt tccattttca ttcagtttac aaatccagac    900

tgtttgaatt ttccttggat gatcttccat ctgaatttca gcaagtaaac attactccat    960

caaaatttat tttgaagcca agaccaaaaa ggagtaaacg gcagcttcgt cgatatcctc   1020

gtaatgtaga agaagaaacc aaatacattg aactgatgat tgtgaatgat caccttatgt   1080

ttaaaaaaca tcggctttcc gttgtacata ccaataccta tgcgaaatct gtggtgaaca   1140

tggcagattt aatatataaa gaccaactta agaccaggat agtattggtt gctatggaaa   1200

cctgggcgac tgacaacaag tttgccatat ctgaaaatcc attgatcacc ctacgtgagt   1260

ttatgaaata caggagggat tttatcaaag agaaaagtga tgcagttcac cttttttcgg   1320

gaagtcaatt tgagagtagc cggagcgggg cagcttatat tggtgggatt tgctcgttgc   1380

tgaaaggagg aggcgtgaat gaatttggga aaactgattt aatggctgtt acacttgccc   1440

agtcattagc ccataatatt ggtattatct cagacaaaag aaagttagca agtggtgaat   1500

gtaaatgcga ggacacgtgg tccgggtgca taatgggaga cactggctat tatcttccta   1560

aaaagttcac ccagtgtaat attgaagagt atcatgactt cctgaatagt ggaggtggtg   1620

cctgcctttt caacaaacct tctaagcttc ttgatcctcc tgagtgtggc aatggcttca   1680

ttgaaactgg agaggagtgt gattgtggaa ccccggccga atgtgtcctt gaaggagcag   1740

agtgttgtaa gaaatgcacc ttgactcaag actctcaatg cagtgacggt ctttgctgta   1800

aaaagtgcaa gtttcagcct atgggcactg tgtgccgaga agcagtaaat gattgtgata   1860

ttcgtgaaac gtgctcagga aattcaagcc agtgtgcccc taatattcat aaaatggatg   1920

gatattcatg tgatggtgtt cagggaattt gctttggagg aagatgcaaa accagagata   1980

gacaatgcaa atacatttgg gggcaaaagg tgacagcatc agacaaatat tgctatgaga   2040

aactgaatat tgaagggacg gagaagggta actgtgggaa agacaaagac acatggatac   2100

agtgcaacaa acgggatgtg ctttgtggtt accttttgtg taccaatatt ggcaatatcc   2160

caaggcttgg agaactcgat ggtgaaatca catctacttt agttgtgcag caaggaagaa   2220

cattaaactg cagtggtggg catgttaagc ttgaagaaga tgtagatctt ggctatgtgg   2280

aagatgggac accttgtggt ccccaaatga tgtgcttaga acacaggtgt cttcctgtgg   2340

cttctttcaa ctttagtact tgcttgagca gtaaagaagg cactatttgc tcaggaaatg   2400

gagtttgcag taatgagctg aagtgtgtgt gtaacagaca ctggataggt tctgattgca   2460

acacttactt ccctcacaat gatgatgcaa agactggtat cactctgtct ggcaatggtg   2520

ttgctggcac caatatcata ataggcataa ttgctggcac cattttagtg ctggccctca   2580

tattaggaat aactgcgtgg ggttataaaa actatcgaga acagagacag ttaccccagg   2640

gagattatgt aaaaaagcct ggagatggtg actcttttta tagcgacatt cctcccggag   2700

tcagcacaaa ctcagcatct agttctaaga agaggtcaaa tgggctctct cattcttgga   2760

gtgaaaggat tccagacaca aaacatattt cagacatctg tgaaaatggg cgacctcgaa   2820

gtaactcttg gcaaggtaac ctgggaggca acaaaaagaa aatcagaggc aaaagattta   2880

gacctcggtc taattcaact gagactttat ctcctgccaa gtctccttct tcatcaactg   2940

ggtctattgc ctccagcaga aaataccctt acccaatgcc tccacttcct gatgaggaca   3000

agaaagtgaa ccgacaaagt gccaggctat gggagacatc catttaagat caactgttta   3060

catgtgatac atcgaaaact gtttacttca acttttatag aaacccaggc tcatggaatc   3120

actgcaaatc tatctgctct tcagacaata cgaagaccct ctgagatgct acagaggaga   3180

ggaagcggag tttcacatct ggttaccatt ttctttttgt cattggctta ggatttaact   3240

aaccatgaaa agaactactg aaatattaca ctataacatg gaacaataaa ggtactggta   3300

tgttaatgga taatccgcat gacagataat atgtagaaat attcataaag ttaactcaca   3360

tgacccaaat gtagcaagtt tcctaaggta caatagtgga ttcagaactt gacgttctga   3420

ggcacatcct cactgtaaac agtaatgcta tatgcatgaa gcttctgttt attgttttcc   3480

atatttaagg aaacaacatc ccataataga aatgagcatg cagggctaag gcatatagga   3540

tttttctgca ggactttaaa gctttgaaag gccaatatcc cataggctaa ctttaaacat   3600

gtatttttat ttttgttttg ttttttactt ttcatattta tattagcata caaggacaat   3660

tgtatatatg taacattttt aaaattttaa aaaaatgcag ctgttacaca caagtgtatt   3720

ttgccaaatg cctaaaaatt ccgtcacaat cacatcatcg tcatccatcc agtgatcttc   3780

aaagactata agcaggtaat gtaaatatag tggtcaatgc tgtaaatgtg tctctccata   3840

attcgtattt gtccaaaaca tgtgatatcc ctttaacctg tgcacagtct ggaggcagtt   3900

ttattgagtg agtagttgag tgagagaaca aaatgcccag caaaacttct ggcctccaca   3960

gtttgctgat gcaggagccc actctgctgc cgatgggctg ctccctggaa atcatctatc   4020

ccatccgtcc atcccatctc atcccagtga gccagcccct cagcagtgtg tgctgctgag   4080

attaagcaag tgcaccaaag acacatgaga caacgtactg ccagtgagct ggtagcttct   4140

ggtttgccaa tactctaacc ctttgtggcc tgaagttttg ttccttggca aaactttgta   4200

gtcaccctta tctgtgaaat gaatgacttg ttttaacaaa aacaactttg acactgttga   4260

ttaagaatat ttgtcatcac tgggatgtga atcccaacaa gtcattctgc actgactctg   4320

aagcaagatg acggaagatt ctactgtttg agttgagcag cttcaaccat tcataaaggg   4380

ttaagttaga tctaaaccac agagatgcag catctgcgaa gttacactaa cagctggtgg   4440

gggaaagaat ctgatgcttt gaaacatata tttttaatcc ataggaaaat aagattctat   4500

tttaaaagac ccttctttaa aaccaaagtt tgatagctgt tataatggca gatctgtcat   4560

tccaaaagaa agctagctac cctagtgagg ctggagattg atgggctcaa tcacatggtc   4620

tgctctgaag tatacttctg atttcctcat ttgctgtgtg ttcttaagag gaatggaatc   4680

tgcagacagg ttttcagata tactctctta aatttgatcc tctcccatag tatccatgga   4740

caaaatccat atcatcttca tatgtaatca atttgattac atatcatgcc caaactgaag   4800

ggccgagtta gaaggcagca ttttatactg tgtgtttatg tcttctgtaa tggacctctc   4860

ttttgaaagt ctttgaaatg tttggaaagc aatttaatga tccaaaatta cataatgtaa   4920

aacagcattt ttcatgacag gaagggatgt gattgttgat atgaccataa agcgatccat   4980

caggccaagg tttgggtgag tgttgggcag tgttgccaca tagctcaagc caagaacaga   5040

agggcagaca gattgaaaga tgtagcaaat aaagtgactt tttaccaaga tcactgtaac   5100

gtgcactgaa tgtttcctgg tactgagtgt acaaaaggct aatgctataa ggtttatttt   5160

gactataaaa gagtttatag atttgaatat aaggtgcctc atgtaaatat gcttcctagt   5220

tacaggtaca caaactctaa tttgaaagaa tccacaaatg gctagctgag aagttaacag   5280

atctctatca ttcgtctgtg tgtctttctt ccctcaccta tttttacatg aaattattat   5340

ttcaaatgaa aatcatgatc atgtgccttt tgggagacat ggtttctcta gaggtatata   5400

gtttgtaatt acccgccttg gtaataacct tcctgtggaa ctgactaaaa atttttgttt   5460

tatttgtaga gattatgatt tgaggtatac agtaacttta atgttctatt cttggaatct   5520

actctatctc ccatgtttaa acattcttag agccatttgt gggattcatt gacaaattta   5580

tagtctcaag ggagagtttc aagaagtatc tatatgtata ctcatggttg gggttctaga   5640

ggcattacat ctaaatattt atgacttttc atccaccgag gtaggtagca ttaaatatac   5700

aagcacagca ttatttctct ttaaatatct attttggaga gaaactttga ggccgtatca   5760

cagtttatat catgcaacta atatttatat ttcccaatcc actacaaaat cattgctaag   5820

cagaagagag cagttatttg gcctttatgt tccattgtat gcctttttcc cctcttccag   5880

ttttatgcat tgataagact acagattggc accctgctgc ctgagaagtt ccatttatcc   5940

atagtcattg cagtgcagta aaccctgatt taaaggaaca tttaagtctc tccagtaagt   6000

gtgaacagga aggcatggga tagaagagag tccttatgga gtggactggc cacatgaact   6060

gtcctccagc cactctttat ttagatggga agtggcatgg tcctctgaac gctgcaggct   6120

ggaaatgatc cccagggcac atgcaatctg tggaaaggaa tacatcggac agtgcaacat   6180

ggtgagggct ttcaatttgc tgtggttgct gtatttttaa caagacaccc ggagcttcga   6240

ttaggaataa cctatcatta gagttgttcc tttaaaaaat gttgatgaat aaagcaaatg   6300

tgggtttaaa atgccaactt atttttcact ttgatattgg tgctttatta agtgatacca   6360

tagtttctct ctcttttccc tgttacttta aaaagaattt taaaattgtg tttgtatata   6420

aggtcagtct ggcatagaat ttctgaaagt aacattaata ggatttctaa agaagttgtc   6480

agaaagacaa aattggatat tctctgcact ttcagagaag gactatttat gtttgaattt   6540

cataacaggc ttacatttct tttctattga ttcccttgca tatctacata atttaatcct   6600

gtctattgtc ccagatctct tgtggctact ttacctgtta ccttttttgg gattttgttc   6660

tttatgtttt acagttacct tcggaccaga agatatatgg tatttttatt cacttttttc   6720

agtgttttaa aataaggttt gttcatttat tcattttatc cattcatttc ctattgtcgt   6780

atagttctaa ccatatatat agtactttaa atattttctt atgttattat ttaacacaat   6840

aataaattct tatctaaaga aaagattatt ttactttatt ttacttaaag gaaagagaat   6900

ttattggcag gatattgagt agcttgtaga gtatatggaa ggggagagcc aagttaggaa   6960

ctggcaggag cgaggaggga caagacagct gcctgcacag tctgatagga cacatctggc   7020

tgctgccact ggatgcccac atgggcagcg tgttgtaaat atcaccctac cagttggtaa   7080

gttggcatga attttccatg aaacacttga ctgccatttg cagcatcata tctacttttt   7140

atgcacctaa ttatattttt cctttcactt ttatgttttt ttctaaaact gccacctaaa   7200

tacctttcca ctccgttaaa tgtatggagt caagataaat ttctcattct tgctctacag   7260

tttaagatgt ataagaagta aacacttccg tggaataggg cttaatttgg ggctcaaatg   7320

ttttgttttc ctcctgagat gtttttgaat ggataagact actctggttt tggatgcagc   7380

aacttttctc ctggcatgga agaactaagg actttgataa acagtttccc attgatagta   7440

taatataatg aggggcccag tctgctcttg tgaaaattgg ctgagcggca gcagcccatc   7500

ccagctgtgt gtgagtagcc ccgctgttaa aagtacacct gctgggaatt gttggcacat   7560

gctcatagca tatgctctgt gggggaggtg cttttaattc caagaggagc ttttctccca   7620

catctgcgga tgcagaacaa agatgcagca ggactttaga aaacaggagt gtttctactg   7680

acattttatt cattgctttg ttagtcccgc aaatggagca acttctggtt gtttgtaagc   7740

agaaaaacaa aacattcaaa accaaaaacc taattagtac ttttgtcctt tatatcccta   7800

ggatgctcta gggagtagag gtggcaggca tctttatctt cacccactgg cacattagca   7860

gcttatgcaa cttaggaagt cactgggaga tgagtcctaa aagcctgaat ttcaggatgg   7920

ggaggagata agaagcagag aactttggga gaccatgggg catttagtcc tggcatagac   7980

acagaatgga tattcacagg aagattcctg aggccagata tgcaggagag cacacattgt   8040

cacaaggggt gtggtgggaa gagaggtgct ggatgcctaa gacagacttc tgtgcttggc   8100

agattgactg agtgttgact ctgaatactt tgtggtccag tccataatag gccagtcact   8160

cctgcctgat gcatccctgt tgcactgttc ataaaacctg tatcatatgg ggaagcttca   8220

aggctggcag gcttttcatc aagtaatcat cattccatgt tcctacgtat ccttgaaatc   8280

aaaaccaggc aatatgtgtg tttttggttt tgttttacaa aaaggcatac aatgagacga   8340

attcttaaga taatgcacat acagaatcat caataaagtt tcaaagagtt tatgaagaaa   8400

aggtattttc ctttcttgta aaaaatgtta tatatatata atattctgat ctgcattcac   8460

cttagggctt agcctcttat tttatgaatt ttcaggctgt gatttgtgtt ggatggctaa   8520

gctctaaaat aatgcaaata gccccaatct ttaaatatag cggtgctaag ttgaacaagt   8580

aacacaatac agaaaatgct gatatgaata cttagtaata atacaaaagt tcctgctaaa   8640

ttatatatgt gtatcactgc ctgactagaa accccacttt tcttttctaa tccagcacaa   8700

aatcaaactc tgattctaca accagtcttt ttaaagggca aaaatgactc aacacctttg   8760

ttttgtatgg aaaacttttt tttttacact aactgcaaaa ctgctttaaa aaaaggctta   8820

ttcaggatag ataagcatgt actccttttt taacttgctg gaagacttgc ccctccaaac   8880

tagcaccccc aaaagacaac ttctttcaga aacggggtgt tttacctaaa catagtagct   8940

tacatgttag ccagcagtag gtcggcacta gtgttttcca cggttatcac ctttgacagg   9000

tgatgtgcat ctatagatag tggaagccac cccatgagga ggtgttaata gcagcatggt   9060

ttcacttttg gtaatcaggt aatcatgtgt atatacttag attcgcatta ttttaacatt   9120

tctctgctac tctgcacttc aggttcgtta agctatttta ataattactg gggttatggc   9180

aaacaccaat ggaaatgtat atggcaactg ctttcctgag caagtgtgat ttgttttatg   9240

gctgttcaag ttataaaatt gttcttacat tgtaggtaaa caaaatcttg atgtttttaa   9300

aggtcactgt aacttaaggt tcaaatttct ggcacagttt tattagtatt cacttcggaa   9360

gctaataaga taccatggtt ttctatgtta ctcccattgt aacattagta aagtgacttt   9420

caataaaaga tttatgttat tttga                                         9445


<210>  5403
<211>  906
<212>  PRT
<213>  Homo sapiens

<400>  5403

Met Gln Ala Ala Val Ala Val Ser Val Pro Phe Leu Leu Leu Cys Val 
1               5                   10                  15


Leu Gly Thr Cys Pro Pro Ala Arg Cys Gly Gln Ala Gly Asp Ala Ser 
            20                  25                  30


Leu Met Glu Leu Glu Lys Arg Lys Glu Asn Arg Phe Val Glu Arg Gln 
        35                  40                  45


Ser Ile Val Pro Leu Arg Leu Ile Tyr Arg Ser Gly Gly Glu Asp Glu 
    50                  55                  60


Ser Arg His Asp Ala Leu Asp Thr Arg Val Arg Gly Asp Leu Gly Gly 
65                  70                  75                  80


Pro Gln Leu Thr His Val Asp Gln Ala Ser Phe Gln Val Asp Ala Phe 
                85                  90                  95


Gly Thr Ser Phe Ile Leu Asp Val Val Leu Asn His Asp Leu Leu Ser 
            100                 105                 110


Ser Glu Tyr Ile Glu Arg His Ile Glu His Gly Gly Lys Thr Val Glu 
        115                 120                 125


Val Lys Gly Gly Glu His Cys Tyr Tyr Gln Gly His Ile Arg Gly Asn 
    130                 135                 140


Pro Asp Ser Phe Val Ala Leu Ser Thr Cys His Gly Leu His Gly Met 
145                 150                 155                 160


Phe Tyr Asp Gly Asn His Thr Tyr Leu Ile Glu Pro Glu Glu Asn Asp 
                165                 170                 175


Thr Thr Gln Glu Asp Phe His Phe His Ser Val Tyr Lys Ser Arg Leu 
            180                 185                 190


Phe Glu Phe Ser Leu Asp Asp Leu Pro Ser Glu Phe Gln Gln Val Asn 
        195                 200                 205


Ile Thr Pro Ser Lys Phe Ile Leu Lys Pro Arg Pro Lys Arg Ser Lys 
    210                 215                 220


Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr Lys Tyr 
225                 230                 235                 240


Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys His Arg 
                245                 250                 255


Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val Asn Met 
            260                 265                 270


Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val Leu Val 
        275                 280                 285


Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser Glu Asn 
    290                 295                 300


Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp Phe Ile 
305                 310                 315                 320


Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln Phe Glu 
                325                 330                 335


Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser Leu Leu 
            340                 345                 350


Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met Ala Val 
        355                 360                 365


Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser Asp Lys 
    370                 375                 380


Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp Ser Gly 
385                 390                 395                 400


Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe Thr Gln 
                405                 410                 415


Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly Gly Ala 
            420                 425                 430


Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu Cys Gly 
        435                 440                 445


Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr Pro Ala 
    450                 455                 460


Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr Leu Thr 
465                 470                 475                 480


Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys Lys Phe 
                485                 490                 495


Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys Asp Ile 
            500                 505                 510


Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn Ile His 
        515                 520                 525


Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys Phe Gly 
    530                 535                 540


Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp Gly Gln 
545                 550                 555                 560


Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn Ile Glu 
                565                 570                 575


Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp Ile Gln 
            580                 585                 590


Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr Asn Ile 
        595                 600                 605


Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr Ser Thr 
    610                 615                 620


Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly His Val 
625                 630                 635                 640


Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly Thr Pro 
                645                 650                 655


Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro Val Ala 
            660                 665                 670


Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr Ile Cys 
        675                 680                 685


Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys Asn Arg 
    690                 695                 700


His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn Asp Asp 
705                 710                 715                 720


Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly Thr Asn 
                725                 730                 735


Ile Ile Ile Gly Ile Ile Ala Gly Thr Ile Leu Val Leu Ala Leu Ile 
            740                 745                 750


Leu Gly Ile Thr Ala Trp Gly Tyr Lys Asn Tyr Arg Glu Gln Arg Gln 
        755                 760                 765


Leu Pro Gln Gly Asp Tyr Val Lys Lys Pro Gly Asp Gly Asp Ser Phe 
    770                 775                 780


Tyr Ser Asp Ile Pro Pro Gly Val Ser Thr Asn Ser Ala Ser Ser Ser 
785                 790                 795                 800


Lys Lys Arg Ser Asn Gly Leu Ser His Ser Trp Ser Glu Arg Ile Pro 
                805                 810                 815


Asp Thr Lys His Ile Ser Asp Ile Cys Glu Asn Gly Arg Pro Arg Ser 
            820                 825                 830


Asn Ser Trp Gln Gly Asn Leu Gly Gly Asn Lys Lys Lys Ile Arg Gly 
        835                 840                 845


Lys Arg Phe Arg Pro Arg Ser Asn Ser Thr Glu Thr Leu Ser Pro Ala 
    850                 855                 860


Lys Ser Pro Ser Ser Ser Thr Gly Ser Ile Ala Ser Ser Arg Lys Tyr 
865                 870                 875                 880


Pro Tyr Pro Met Pro Pro Leu Pro Asp Glu Asp Lys Lys Val Asn Arg 
                885                 890                 895


Gln Ser Ala Arg Leu Trp Glu Thr Ser Ile 
            900                 905


<210>  5404
<211>  434
<212>  DNA
<213>  Homo sapiens

<400>  5404
cagaaaacat atgttgatcc caaacatgca atgacatcca tataaacctt gcaaaatgat     60

ggctgtgatg acacccagtg atggtctttc tcaactctct gtacctcatc tcactcatca    120

gagactttgg agcctcagtt gccttgcaat gctgtttcag gctgtactca ttctttctgc    180

accacaaatg tcatgccttc tcaagtgttt ttatgccctg gacccattgc atccagtgat    240

gtcagaggaa ttctcagctc aatatcgtca catgatggat cagagataca gaactagaat    300

tcatgaggga tacatatctc aagtgaaagg tgcatatcta cggattgtcc acaagaaacc    360

aatcagttat gcaaaatctt ttccaaagga aatgggaaat taaggaaaaa agtgaataaa    420

actttacaaa aatg                                                      434


<210>  5405
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  5405

Met Met Ala Val Met Thr Pro Ser Asp Gly Leu Ser Gln Leu Ser Val 
1               5                   10                  15


Pro His Leu Thr His Gln Arg Leu Trp Ser Leu Ser Cys Leu Ala Met 
            20                  25                  30


Leu Phe Gln Ala Val Leu Ile Leu Ser Ala Pro Gln Met Ser Cys Leu 
        35                  40                  45


Leu Lys Cys Phe Tyr Ala Leu Asp Pro Leu His Pro Val Met Ser Glu 
    50                  55                  60


Glu Phe Ser Ala Gln Tyr Arg His Met Met Asp Gln Arg Tyr Arg Thr 
65                  70                  75                  80


Arg Ile His Glu Gly Tyr Ile Ser Gln Val Lys Gly Ala Tyr Leu Arg 
                85                  90                  95


Ile Val His Lys Lys Pro Ile Ser Tyr Ala Lys Ser Phe Pro Lys Glu 
            100                 105                 110


Met Gly Asn 
        115


<210>  5406
<211>  538
<212>  DNA
<213>  Homo sapiens

<400>  5406
agccactatt tttaatgaaa aaaattgaat caatcattgg gaagaagaga tttttttaat     60

tccacaaatg aagaggccca ctagtagcct tcaattttct gaaaagatta atttcagaag    120

acataggaag ttgattgaga cagagacaac tcagaaagtt ttgatatatc tttcaacttg    180

gagtgaaact gctgataaag tagattttaa agagttgaac atttagaaaa gaaagggcag    240

aagattgaga gatatacatg tgatttataa atggagacaa aaggggtcct tatgagaaga    300

agagaagaga cacagaagca aaggcacaca ggaagatgtg atgatggagg tagagattgg    360

aatgatgtgt ctagaggtca aggaatgcca aagattgcca gcaaacacca gaagctggga    420

gaatcaagga aggattctcc actgcaggtt tcagagggag catggccctg ccaacatctt    480

gaagtcagac tcctaggctc cagaactgtg agacaataaa tttccattgt tttaagcc      538


<210>  5407
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  5407

Met Glu Thr Lys Gly Val Leu Met Arg Arg Arg Glu Glu Thr Gln Lys 
1               5                   10                  15


Gln Arg His Thr Gly Arg Cys Asp Asp Gly Gly Arg Asp Trp Asn Asp 
            20                  25                  30


Val Ser Arg Gly Gln Gly Met Pro Lys Ile Ala Ser Lys His Gln Lys 
        35                  40                  45


Leu Gly Glu Ser Arg Lys Asp Ser Pro Leu Gln Val Ser Glu Gly Ala 
    50                  55                  60


Trp Pro Cys Gln His Leu Glu Val Arg Leu Leu Gly Ser Arg Thr Val 
65                  70                  75                  80


Arg Gln 



<210>  5408
<211>  3384
<212>  DNA
<213>  Homo sapiens

<400>  5408
ctattgaagc cacctgctca ggacaatgaa attcttcagt tacattctgg tttatcgccg     60

atttctcttc gtggttttca ctgtgttggt tttactacct ctgcccatcg tcctccacac    120

caagcttatt ctgacttttc caagatgaag atgaagagca ggccagtggc atgggccaga    180

tgcagtcaga tgactgactg accaggaggg cctccgtcca gtgaccagtc tcagaattta    240

aaggaccctt cccccttact tatgcttgta ctcagcccag gaagcagaat gtgcctacac    300

actctttgtg gtcgccacat tttggctcac agaagcattg cctctgtcgg taacagcttt    360

gctacctagt ttaatgttac ccatgtttgg gatcatgcct tctaagaagg tggcatctgc    420

ttatttcaag gattttcact tactgctaat tggagttatc tgtttagcaa catccataga    480

aaaatggaat ttgcacaaga gaattgctct gaaaatggtg atgatggttg gtgtaaatcc    540

tgcatggctg acgctggggt tcatgagcag cactgccttt ttgtctatgt ggctcagcaa    600

cacctcgacg gctgccatgg tgatgcccat tgcggaggct gtagtgcagc agatcatcaa    660

tgcagaagca gaggtcgagg ccactcagat gacttacttc aacggatcaa ccaaccacgg    720

actagaaatt gatgaaagtg ttaatggaca tgaaataaat gagaggaaag agaaaacaaa    780

accagttcca ggatacaata atgatacagg gaaaatttca agcaaggtgg agttggaaaa    840

gtacttgcaa gtgaggtgac caaaaaacag ctttagactc ttaaacttag tgtttaaaat    900

gagaaggctg agagacagtc tgcttatgga gaaagttgga gtatttcccc agtgccccaa    960

ccccctgcca cttgtaccat cacagtcgaa agaagggaag agtctcctac ttaacaagga   1020

agaggaagaa tcaaaccaac aaagggtgtt tacagggtca tgggtgagaa aaagaatgaa   1080

gttgcttttg gcttacaccc tagaaagtca tctcttaaat aaaacactta catttggact   1140

agtgattccc caagtgaaac catttcagga tgtgccattg tccaagaact caggcatgag   1200

aaccaaatat cgaacaaaga agggccacgt gacacgtaaa cttacgtgtt tgtgcattgc   1260

ctactcttct accattggtg gactgacaac aatcactggt acctccacca acttgatctt   1320

tgcagagtat ttcaatacac gctatcctga ctgtcgttgc ctcaactttg gatcatggtt   1380

tacgttttcc ttcccagctg cccttatcat tctactctta tcctggatct ggcttcagtg   1440

gcttttccta ggattcaatt ttaaggagat gttcaaatgt ggcaaaacca aaacagtcca   1500

acaaaaagct tgtgctgagg tgattaagca agaataccaa aagcttgggc caataaggta   1560

tcaagaaatt gtgaccttgg tcctcttcat tataatggct ctgctatggt ttagtcgaga   1620

ccccggattt gttcctggtt ggtctgcact tttttcagag taccctggtt ttgctacaga   1680

ttcaactgtt gctttactta tagggctgct attctttctt atcccagcta agacactgac   1740

taaaactaca cctacaggag aaattgttgc ttttgattac tctccactga ttacttggaa   1800

agaattccag tcattcatgc cctgggatat agccattctt gttggtggag ggtttgccct   1860

ggcagatggt tgtgaggagt ctggattatc taagtggata ggaaataaat tatctcctct   1920

gggttcatta ccagcatggc taataattct gatatcttct ttgatggtga catctttaac   1980

tgaggtagcc agcaatccag ctaccattac actctttctc ccaatattat ctccattggc   2040

cgaagccatt catgtgaacc ctctttatat tctgatacct tctactctgt gtacttcatt   2100

tgcattcctc ctaccagtag caaatccacc caatgctatt gtcttttcat atggtcatct   2160

gaaagtcatt gacatggtta aagctggact tggtgtcaac attgttggtg ttgctgtggt   2220

tatgcttggc atatgtactt ggattgtacc catgtttgac ctctacactt acccttcgtg   2280

ggctcctgct atgagtaatg agaccatgcc ataataagca caaaatttct gactatcttg   2340

cggtaatttc tggaagacat taatgattga ctgtaaaatg tggctctaaa taactaatga   2400

cacacattta aatcagttat ggtgtagctg ctgcaattcc tgtgaatacc cgaaacctgc   2460

tgttataact cagagtccat atttgttatt gcagtgcaac taaagagcat ctatgtgcct   2520

tcatcaagaa gcccatgttt tgagattttg ctcatgaacc atctgcaact tgcttcatca   2580

taagaataat ttataacttg accttcaaag agattagagc atttgtttca tcttacagtt   2640

ggagttcaat gtaacatttt aaatgcaatt tattatttca gaaatttccc atgaaactaa   2700

aaatagaaaa taagatatac aagttaattc ggtacttgga taaatcattt ctgcattgtt   2760

gttccagaga atttgctgag aaatcaaagc catggtcatc tggtgatgaa gagaaaagtt   2820

taatctaaat gatatgtgca tttcctcatt taaaaaatcc aattggatta ttcttaatat   2880

atacatgtaa tatgaaaatt gagattgaag cactaattcc aaaattatgg ctgaatatac   2940

taaataacag aaaagttaca gataagaatt tatttctact gaactctata gttagtgtaa   3000

tataattcat atttttatga tattggcaca ctgagaaatt cattttgtag agctatggat   3060

aaggcttgct atgatttgca ctattagtac agtatagtta gaaaggaaag ctgaacacta   3120

taaaactatt aacatatttt cgtatatgag taacaacttt gcttaagtgt ttatcttagt   3180

tcagaaatac ataatgtcat atgttaaaaa taaagagatg tagaaatcta aatgaattat   3240

cactgtgtat acagacagaa aaatcacata actctggtgt gttaacattg caatgaaaaa   3300

atgaaaaaaa gaaggaaaaa agaataagaa tgaaaactgc tgacgtatta caaaacagaa   3360

aaataaatga tttaaaatca aatc                                          3384


<210>  5409
<211>  471
<212>  PRT
<213>  Homo sapiens

<400>  5409

Met Arg Arg Leu Arg Asp Ser Leu Leu Met Glu Lys Val Gly Val Phe 
1               5                   10                  15


Pro Gln Cys Pro Asn Pro Leu Pro Leu Val Pro Ser Gln Ser Lys Glu 
            20                  25                  30


Gly Lys Ser Leu Leu Leu Asn Lys Glu Glu Glu Glu Ser Asn Gln Gln 
        35                  40                  45


Arg Val Phe Thr Gly Ser Trp Val Arg Lys Arg Met Lys Leu Leu Leu 
    50                  55                  60


Ala Tyr Thr Leu Glu Ser His Leu Leu Asn Lys Thr Leu Thr Phe Gly 
65                  70                  75                  80


Leu Val Ile Pro Gln Val Lys Pro Phe Gln Asp Val Pro Leu Ser Lys 
                85                  90                  95


Asn Ser Gly Met Arg Thr Lys Tyr Arg Thr Lys Lys Gly His Val Thr 
            100                 105                 110


Arg Lys Leu Thr Cys Leu Cys Ile Ala Tyr Ser Ser Thr Ile Gly Gly 
        115                 120                 125


Leu Thr Thr Ile Thr Gly Thr Ser Thr Asn Leu Ile Phe Ala Glu Tyr 
    130                 135                 140


Phe Asn Thr Arg Tyr Pro Asp Cys Arg Cys Leu Asn Phe Gly Ser Trp 
145                 150                 155                 160


Phe Thr Phe Ser Phe Pro Ala Ala Leu Ile Ile Leu Leu Leu Ser Trp 
                165                 170                 175


Ile Trp Leu Gln Trp Leu Phe Leu Gly Phe Asn Phe Lys Glu Met Phe 
            180                 185                 190


Lys Cys Gly Lys Thr Lys Thr Val Gln Gln Lys Ala Cys Ala Glu Val 
        195                 200                 205


Ile Lys Gln Glu Tyr Gln Lys Leu Gly Pro Ile Arg Tyr Gln Glu Ile 
    210                 215                 220


Val Thr Leu Val Leu Phe Ile Ile Met Ala Leu Leu Trp Phe Ser Arg 
225                 230                 235                 240


Asp Pro Gly Phe Val Pro Gly Trp Ser Ala Leu Phe Ser Glu Tyr Pro 
                245                 250                 255


Gly Phe Ala Thr Asp Ser Thr Val Ala Leu Leu Ile Gly Leu Leu Phe 
            260                 265                 270


Phe Leu Ile Pro Ala Lys Thr Leu Thr Lys Thr Thr Pro Thr Gly Glu 
        275                 280                 285


Ile Val Ala Phe Asp Tyr Ser Pro Leu Ile Thr Trp Lys Glu Phe Gln 
    290                 295                 300


Ser Phe Met Pro Trp Asp Ile Ala Ile Leu Val Gly Gly Gly Phe Ala 
305                 310                 315                 320


Leu Ala Asp Gly Cys Glu Glu Ser Gly Leu Ser Lys Trp Ile Gly Asn 
                325                 330                 335


Lys Leu Ser Pro Leu Gly Ser Leu Pro Ala Trp Leu Ile Ile Leu Ile 
            340                 345                 350


Ser Ser Leu Met Val Thr Ser Leu Thr Glu Val Ala Ser Asn Pro Ala 
        355                 360                 365


Thr Ile Thr Leu Phe Leu Pro Ile Leu Ser Pro Leu Ala Glu Ala Ile 
    370                 375                 380


His Val Asn Pro Leu Tyr Ile Leu Ile Pro Ser Thr Leu Cys Thr Ser 
385                 390                 395                 400


Phe Ala Phe Leu Leu Pro Val Ala Asn Pro Pro Asn Ala Ile Val Phe 
                405                 410                 415


Ser Tyr Gly His Leu Lys Val Ile Asp Met Val Lys Ala Gly Leu Gly 
            420                 425                 430


Val Asn Ile Val Gly Val Ala Val Val Met Leu Gly Ile Cys Thr Trp 
        435                 440                 445


Ile Val Pro Met Phe Asp Leu Tyr Thr Tyr Pro Ser Trp Ala Pro Ala 
    450                 455                 460


Met Ser Asn Glu Thr Met Pro 
465                 470


<210>  5410
<211>  2895
<212>  DNA
<213>  Homo sapiens

<400>  5410
atttggagga cactattgaa gccacctgct caggacaatg aaattcttca gttacattct     60

ggtttatcgc cgatttctct tcgtggtttt cactgtgttg gttttactac ctctgcccat    120

cgtcctccac accaaggaag cagaatgtgc ctacacactc tttgtggtcg ccacattttg    180

gctcacagaa gcattgcctc tgtcggtaac agctttgcta cctagtttaa tgttacccat    240

gtttgggatc atgccttcta agaaggtggc atctgcttat ttcaaggatt ttcacttact    300

gctaattgga gttatctgtt tagcaacatc catagaaaaa tggaatttgc acaagagaat    360

tgctctgaaa atggtgatga tggttggtgt aaatcctgca tggctgacgc tggggttcat    420

gagcagcact gcctttttgt ctatgtggct cagcaacacc tcgacggctg ccatggtgat    480

gcccattgcg gaggctgtag tgcagcagat catcaatgca gaagcagagg tcgaggccac    540

tcagatgact tacttcaacg gatcaaccaa ccacggacta gaaattgatg aaagtgttaa    600

tggacatgaa ataaatgaga ggaaagagaa aacaaaacca gttccaggat acaataatga    660

tacagggaaa atttcaagca aggtggagtt ggaaaagaac tcaggcatga gaaccaaata    720

tcgaacaaag aagggccacg tgacacgtaa acttacgtgt ttgtgcattg cctactcttc    780

taccattggt ggactgacaa caatcactgg tacctccacc aacttgatct ttgcagagta    840

tttcaataca cgctatcctg actgtcgttg cctcaacttt ggatcatggt ttacgttttc    900

cttcccagct gcccttatca ttctactctt atcctggatc tggcttcagt ggcttttcct    960

aggattcaat tttaaggaga tgttcaaatg tggcaaaacc aaaacagtcc aacaaaaagc   1020

ttgtgctgag gtgattaagc aagaatacca aaagcttggg ccaataaggt atcaagaaat   1080

tgtgaccttg gtcctcttca ttataatggc tctgctatgg tttagtcgag accccggatt   1140

tgttcctggt tggtctgcac ttttttcaga gtaccctggt tttgctacag attcaactgt   1200

tgctttactt atagggctgc tattctttct tatcccagct aagacactga ctaaaactac   1260

acctacagga gaaattgttg cttttgatta ctctccactg attacttgga aagaattcca   1320

gtcattcatg ccctgggata tagccattct tgttggtgga gggtttgccc tggcagatgg   1380

ttgtgaggag tctggattat ctaagtggat aggaaataaa ttatctcctc tgggttcatt   1440

accagcatgg ctaataattc tgatatcttc tttgatggtg acatctttaa ctgaggtagc   1500

cagcaatcca gctaccatta cactctttct cccaatatta tctccattgg ccgaagccat   1560

tcatgtgaac cctctttata ttctgatacc ttctactctg tgtacttcat ttgcattcct   1620

cctaccagta gcaaatccac ccaatgctat tgtcttttca tatggtcatc tgaaagtcat   1680

tgacatggtt aaagctggac ttggtgtcaa cattgttggt gttgctgtgg ttatgcttgg   1740

catatgtact tggattgtac ccatgtttga cctctacact tacccttcgt gggctcctgc   1800

tatgagtaat gagaccatgc cataataagc acaaaatttc tgactatctt gcggtaattt   1860

ctggaagaca ttaatgattg actgtaaaat gtggctctaa ataactaatg acacacattt   1920

aaatcagtta tggtgtagct gctgcaattc ctgtgaatac ccgaaacctg ctgttataac   1980

tcagagtcca tatttgttat tgcagtgcaa ctaaagagca tctatgtgcc ttcatcaaga   2040

agcccatgtt ttgagatttt gctcatgaac catctgcaac ttgcttcatc ataagaataa   2100

tttataactt gaccttcaaa gagattagag catttgtttc atcttacagt tggagttcaa   2160

tgtaacattt taaatgcaat ttattatttc agaaatttcc catgaaacta aaaatagaaa   2220

ataagatata caagttaatt cggtacttgg ataaatcatt tctgcattgt tgttccagag   2280

aatttgctga gaaatcaaag ccatggtcat ctggtgatga agagaaaagt ttaatctaaa   2340

tgatatgtgc atttcctcat ttaaaaaatc caattggatt attcttaata tatacatgta   2400

atatgaaaat tgagattgaa gcactaattc caaaattatg gctgaatata ctaaataaca   2460

gaaaagttac agataagaat ttatttctac tgaactctat agttagtgta atataattca   2520

tatttttatg atattggcac actgagaaat tcattttgta gagctatgga taaggcttgc   2580

tatgatttgc actattagta cagtatagtt agaaaggaaa gctgaacact ataaaactat   2640

taacatattt tcgtatatga gtaacaactt tgcttaagtg tttatcttag ttcagaaata   2700

cataatgtca tatgttaaaa ataaagagat gtagaaatct aaatgaatta tcactgtgta   2760

tacagacaga aaaatcacat aactctggtg tgttaacatt gcaatgaaaa aatgaaaaaa   2820

agaaggaaaa aagaataaga atgaaaactg ctgacgtatt acaaaacaga aaaataaatg   2880

atttaaaatc aaatc                                                    2895


<210>  5411
<211>  595
<212>  PRT
<213>  Homo sapiens

<400>  5411

Met Lys Phe Phe Ser Tyr Ile Leu Val Tyr Arg Arg Phe Leu Phe Val 
1               5                   10                  15


Val Phe Thr Val Leu Val Leu Leu Pro Leu Pro Ile Val Leu His Thr 
            20                  25                  30


Lys Glu Ala Glu Cys Ala Tyr Thr Leu Phe Val Val Ala Thr Phe Trp 
        35                  40                  45


Leu Thr Glu Ala Leu Pro Leu Ser Val Thr Ala Leu Leu Pro Ser Leu 
    50                  55                  60


Met Leu Pro Met Phe Gly Ile Met Pro Ser Lys Lys Val Ala Ser Ala 
65                  70                  75                  80


Tyr Phe Lys Asp Phe His Leu Leu Leu Ile Gly Val Ile Cys Leu Ala 
                85                  90                  95


Thr Ser Ile Glu Lys Trp Asn Leu His Lys Arg Ile Ala Leu Lys Met 
            100                 105                 110


Val Met Met Val Gly Val Asn Pro Ala Trp Leu Thr Leu Gly Phe Met 
        115                 120                 125


Ser Ser Thr Ala Phe Leu Ser Met Trp Leu Ser Asn Thr Ser Thr Ala 
    130                 135                 140


Ala Met Val Met Pro Ile Ala Glu Ala Val Val Gln Gln Ile Ile Asn 
145                 150                 155                 160


Ala Glu Ala Glu Val Glu Ala Thr Gln Met Thr Tyr Phe Asn Gly Ser 
                165                 170                 175


Thr Asn His Gly Leu Glu Ile Asp Glu Ser Val Asn Gly His Glu Ile 
            180                 185                 190


Asn Glu Arg Lys Glu Lys Thr Lys Pro Val Pro Gly Tyr Asn Asn Asp 
        195                 200                 205


Thr Gly Lys Ile Ser Ser Lys Val Glu Leu Glu Lys Asn Ser Gly Met 
    210                 215                 220


Arg Thr Lys Tyr Arg Thr Lys Lys Gly His Val Thr Arg Lys Leu Thr 
225                 230                 235                 240


Cys Leu Cys Ile Ala Tyr Ser Ser Thr Ile Gly Gly Leu Thr Thr Ile 
                245                 250                 255


Thr Gly Thr Ser Thr Asn Leu Ile Phe Ala Glu Tyr Phe Asn Thr Arg 
            260                 265                 270


Tyr Pro Asp Cys Arg Cys Leu Asn Phe Gly Ser Trp Phe Thr Phe Ser 
        275                 280                 285


Phe Pro Ala Ala Leu Ile Ile Leu Leu Leu Ser Trp Ile Trp Leu Gln 
    290                 295                 300


Trp Leu Phe Leu Gly Phe Asn Phe Lys Glu Met Phe Lys Cys Gly Lys 
305                 310                 315                 320


Thr Lys Thr Val Gln Gln Lys Ala Cys Ala Glu Val Ile Lys Gln Glu 
                325                 330                 335


Tyr Gln Lys Leu Gly Pro Ile Arg Tyr Gln Glu Ile Val Thr Leu Val 
            340                 345                 350


Leu Phe Ile Ile Met Ala Leu Leu Trp Phe Ser Arg Asp Pro Gly Phe 
        355                 360                 365


Val Pro Gly Trp Ser Ala Leu Phe Ser Glu Tyr Pro Gly Phe Ala Thr 
    370                 375                 380


Asp Ser Thr Val Ala Leu Leu Ile Gly Leu Leu Phe Phe Leu Ile Pro 
385                 390                 395                 400


Ala Lys Thr Leu Thr Lys Thr Thr Pro Thr Gly Glu Ile Val Ala Phe 
                405                 410                 415


Asp Tyr Ser Pro Leu Ile Thr Trp Lys Glu Phe Gln Ser Phe Met Pro 
            420                 425                 430


Trp Asp Ile Ala Ile Leu Val Gly Gly Gly Phe Ala Leu Ala Asp Gly 
        435                 440                 445


Cys Glu Glu Ser Gly Leu Ser Lys Trp Ile Gly Asn Lys Leu Ser Pro 
    450                 455                 460


Leu Gly Ser Leu Pro Ala Trp Leu Ile Ile Leu Ile Ser Ser Leu Met 
465                 470                 475                 480


Val Thr Ser Leu Thr Glu Val Ala Ser Asn Pro Ala Thr Ile Thr Leu 
                485                 490                 495


Phe Leu Pro Ile Leu Ser Pro Leu Ala Glu Ala Ile His Val Asn Pro 
            500                 505                 510


Leu Tyr Ile Leu Ile Pro Ser Thr Leu Cys Thr Ser Phe Ala Phe Leu 
        515                 520                 525


Leu Pro Val Ala Asn Pro Pro Asn Ala Ile Val Phe Ser Tyr Gly His 
    530                 535                 540


Leu Lys Val Ile Asp Met Val Lys Ala Gly Leu Gly Val Asn Ile Val 
545                 550                 555                 560


Gly Val Ala Val Val Met Leu Gly Ile Cys Thr Trp Ile Val Pro Met 
                565                 570                 575


Phe Asp Leu Tyr Thr Tyr Pro Ser Trp Ala Pro Ala Met Ser Asn Glu 
            580                 585                 590


Thr Met Pro 
        595


<210>  5412
<211>  739
<212>  DNA
<213>  Homo sapiens

<400>  5412
gctaattggg cggagggcgg tggcgctctg gcacgcttgc gcggcgagta gaacgtgtgg     60

cggcggcgga gatcgcgtct ctttcgctcc gtgtcccgct gctgctcctg tgagcgcccg    120

gcgagtccgt cccgtccacc gtccgcagct ggtagccagc ctgcccctcg cctcgactcc    180

ctttcaccaa caccgacacc cacattgaca cctccagtcc ggccagccgc tccactcgtt    240

gcctttgcat ctccacacat ggcgtcctcc gcgcagagcg gcggctcctc cgggggaccc    300

gcggtcccca ccgtgcagcg gggcatcatc aagatggtcc tctcagggtg cgccatcatt    360

gtccgaggtc agcctcgtgg tgggcctcct cctgagcggc agatcaacct cagcaacatt    420

cgtgctggaa atcttgctcg ccgggcagcc gccacacaac ctgatgcaaa ggatacccct    480

gatgagccct gggcatttcc agctcgagag ttccttcgaa agaagctgat tgggaaggaa    540

gtctgtttca cgatagaaaa caagactccc cagggccttg ctggtgtgac ataggcttca    600

gcttcctatc tgtttcccct ggggaatcaa tgaaaacaag gttcatcatt cctctaatag    660

attaaaattt ttttcttgat taacttcact gtggagttgg caagagttgt tatctgttaa    720

tcaaaactgt ttaaataaa                                                 739


<210>  5413
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  5413

Met Ala Ser Ser Ala Gln Ser Gly Gly Ser Ser Gly Gly Pro Ala Val 
1               5                   10                  15


Pro Thr Val Gln Arg Gly Ile Ile Lys Met Val Leu Ser Gly Cys Ala 
            20                  25                  30


Ile Ile Val Arg Gly Gln Pro Arg Gly Gly Pro Pro Pro Glu Arg Gln 
        35                  40                  45


Ile Asn Leu Ser Asn Ile Arg Ala Gly Asn Leu Ala Arg Arg Ala Ala 
    50                  55                  60


Ala Thr Gln Pro Asp Ala Lys Asp Thr Pro Asp Glu Pro Trp Ala Phe 
65                  70                  75                  80


Pro Ala Arg Glu Phe Leu Arg Lys Lys Leu Ile Gly Lys Glu Val Cys 
                85                  90                  95


Phe Thr Ile Glu Asn Lys Thr Pro Gln Gly Leu Ala Gly Val Thr 
            100                 105                 110


<210>  5414
<211>  3538
<212>  DNA
<213>  Homo sapiens

<400>  5414
aattgggcgg agggcggtgg cgctctggca cgcttgcgcg gcgagtagaa cgtgtggcgg     60

cggcggagat cgcgtctctt tcgctccgtg tcccgctgct gctcctgtga gcgcccggcg    120

agtccgtccc gtccaccgtc cgcagctggt agccagcctg cccctcgcct cgactccctt    180

tcaccaacac cgacacccac attgacacct ccagtccggc cagccgctcc actcgttgcc    240

tttgcatctc cacacatggc gtcctccgcg cagagcggcg gctcctccgg gggacccgcg    300

gtccccaccg tgcagcgggg catcatcaag atggtcctct cagggtgcgc catcattgtc    360

cgaggtcagc ctcgtggtgg gcctcctcct gagcggcaga tcaacctcag caacattcgt    420

gctggaaatc ttgctcgccg ggcagccgcc acacaacctg atgcaaagga tacccctgat    480

gagccctggg catttccagc tcgagagttc cttcgaaaga agctgattgg gaaggaagtc    540

tgtttcacga tagaaaacaa gactccccag gggcgagagt atggcatgat ctaccttgga    600

aaagatacca atggggaaaa cattgcagaa tcactggttg cagagggctt agccacccgg    660

agagaaggca tgagagctaa taatcctgag cagaaccggc tttcagaatg tgaagaacaa    720

gcaaaggcag ccaagaaagg gatgtggagt gaggggaacg gttcacatac tatccgggat    780

ctcaagtata ccattgaaaa cccaaggcac tttgtggact cacaccacca gaagcctgtt    840

aatgctatca tcgagcatgt gcgggacggc agtgtggtca gggccctgct cctcccagat    900

tactacctgg ttacagtcat gctgtcaggc atcaagtgcc caacttttcg acgggaagca    960

gatggcagtg aaactccaga gccttttgct gcagaagcca aatttttcac tgagtcgcga   1020

ctgcttcaga gagatgttca gatcattctg gagagctgcc acaaccagaa cattctgggt   1080

accatccttc atccaaatgg caacatcaca gagctcctcc tgaaggaagg tttcgcacgc   1140

tgtgtggact ggtcgattgc agtttacacc cggggcgcag aaaagctgag ggcggcagag   1200

aggtttgcca aagagcgcag gctgagaata tggagagact atgtggctcc cacagctaat   1260

ttggaccaaa aggacaagca gtttgttgcc aaggtgatgc aggttctgaa tgctgatgcc   1320

attgttgtga agctgaactc aggcgattac aagacgattc acctgtccag catccgacca   1380

ccgaggctgg agggggagaa cacccaggat aagaacaaga aactgcgtcc cctgtatgac   1440

attccttaca tgtttgaggc ccgggaattt cttcgaaaaa agcttattgg gaagaaggtc   1500

aatgtgacgg tggactacat tagaccagcc agcccagcca cagagacagt gcctgccttt   1560

tcagagcgta cctgtgccac tgtcaccatt ggaggaataa acattgctga ggctcttgtc   1620

agcaaaggtc tagccacagt gatcagatac cggcaggatg atgaccagag atcatcacac   1680

tacgatgaac tgcttgctgc agaggccaga gctattaaga atggcaaagg attgcatagc   1740

aagaaggaag tgcctatcca ccgtgttgca gatatatctg gggataccca aaaagcaaag   1800

cagttcctgc cttttcttca gcgggcaggt cgttctgaag ctgtggtgga atacgtcttc   1860

agtggttctc gtctcaaact ctatttgcca aaggaaactt gccttatcac cttcttgctt   1920

gcaggcattg aatgccccag aggagcccga aacctcccag gcttggtgca ggaaggagag   1980

cccttcagcg aggaagctac acttttcacc aaggaactgg tgctgcagcg agaggtggag   2040

gtggaggtgg agagcatgga caaggccggc aactttatcg gctggctgca catcgacggt   2100

gccaacctgt ccgtcctgct ggtggagcac gcgctctcca aggtccactt caccgccgaa   2160

cgcagctcct actacaagtc cctgctgtct gccgaggagg ccgcaaagca gaagaaagag   2220

aaggtctggg cccactatga ggagcagccc gtggaggagg tgatgccagt gctggaggag   2280

aaggagcgat ctgctagcta caagcccgtg tttgtgactg agatcactga tgacctgcac   2340

ttctacgtgc aggatgtgga gaccggcacc cagttggaga agctgatgga gaacatgcgc   2400

aatgacattg ccagtcaccc ccctgtagag ggctcctatg ccccccgcag gggagagttc   2460

tgcattgcca aatttgtaga tggagaatgg taccgtgccc gagtagagaa agtcgagtct   2520

cctgccaaaa tacatgtctt ctacattgac tacggcaaca gagaggtcct gccatccacc   2580

cgcctgggta ccctatcacc tgccttcagc actcgggtgc tgccagctca agccacggag   2640

tatgccttcg ccttcatcca ggtgccccaa gatgatgatg cccgcacgga cgccgtggac   2700

agcgtagttc gggatatcca gaacactcag tgcctgctca acgtggaaca cctgagtgcc   2760

ggctgccccc atgtcaccct gcagtttgca gattccaagg gcgatgtggg gctgggcttg   2820

gtgaaggaag ggctggtcat ggtggaggtg cgcaaggaga aacagttcca gaaagtgatc   2880

acagaatacc tgaatgccca agagtcagcc aagagcgcca ggctgaacct gtggcgctat   2940

ggagactttc gagctgatga tgcagacgaa tttggctaca gccgctaagg aggggatcgg   3000

gtttggcccc cagccccgct cacgccagtc cctcttcctc tgccgggagg gtgttttcaa   3060

ctccaaaccc cagagagggg ttgtagattg ggtccagctt tgcttcagtg tgtggaaatg   3120

tctcgtgggg tggcatcggg gctgcggggt ggggacccca aggctttctg gggcagaccc   3180

ttgtcctctg ggatgatggg cactgctatc cacagtctct gccagttggt tttatttgga   3240

ggtttgtggg ctttttttaa aaaaaaaaag tcctcaaatc aggaagaaac atcaaagact   3300

atgtcctagt ggagggagta atcctaacac ccaggctggc cgccagctgg cacctgcctc   3360

tatcccagac tgccctcgtc ccagctctct gtccaactgt tgattatgtg atttttctga   3420

tacgtccatt ctcaaatgcc agtgtgttca catcttcgct ctggccagcc cattctgtat   3480

ttaaagcttt tgaggcccaa taaaatagta cgtgctgtct gcagccctta ttgatcac     3538


<210>  5415
<211>  910
<212>  PRT
<213>  Homo sapiens

<400>  5415

Met Ala Ser Ser Ala Gln Ser Gly Gly Ser Ser Gly Gly Pro Ala Val 
1               5                   10                  15


Pro Thr Val Gln Arg Gly Ile Ile Lys Met Val Leu Ser Gly Cys Ala 
            20                  25                  30


Ile Ile Val Arg Gly Gln Pro Arg Gly Gly Pro Pro Pro Glu Arg Gln 
        35                  40                  45


Ile Asn Leu Ser Asn Ile Arg Ala Gly Asn Leu Ala Arg Arg Ala Ala 
    50                  55                  60


Ala Thr Gln Pro Asp Ala Lys Asp Thr Pro Asp Glu Pro Trp Ala Phe 
65                  70                  75                  80


Pro Ala Arg Glu Phe Leu Arg Lys Lys Leu Ile Gly Lys Glu Val Cys 
                85                  90                  95


Phe Thr Ile Glu Asn Lys Thr Pro Gln Gly Arg Glu Tyr Gly Met Ile 
            100                 105                 110


Tyr Leu Gly Lys Asp Thr Asn Gly Glu Asn Ile Ala Glu Ser Leu Val 
        115                 120                 125


Ala Glu Gly Leu Ala Thr Arg Arg Glu Gly Met Arg Ala Asn Asn Pro 
    130                 135                 140


Glu Gln Asn Arg Leu Ser Glu Cys Glu Glu Gln Ala Lys Ala Ala Lys 
145                 150                 155                 160


Lys Gly Met Trp Ser Glu Gly Asn Gly Ser His Thr Ile Arg Asp Leu 
                165                 170                 175


Lys Tyr Thr Ile Glu Asn Pro Arg His Phe Val Asp Ser His His Gln 
            180                 185                 190


Lys Pro Val Asn Ala Ile Ile Glu His Val Arg Asp Gly Ser Val Val 
        195                 200                 205


Arg Ala Leu Leu Leu Pro Asp Tyr Tyr Leu Val Thr Val Met Leu Ser 
    210                 215                 220


Gly Ile Lys Cys Pro Thr Phe Arg Arg Glu Ala Asp Gly Ser Glu Thr 
225                 230                 235                 240


Pro Glu Pro Phe Ala Ala Glu Ala Lys Phe Phe Thr Glu Ser Arg Leu 
                245                 250                 255


Leu Gln Arg Asp Val Gln Ile Ile Leu Glu Ser Cys His Asn Gln Asn 
            260                 265                 270


Ile Leu Gly Thr Ile Leu His Pro Asn Gly Asn Ile Thr Glu Leu Leu 
        275                 280                 285


Leu Lys Glu Gly Phe Ala Arg Cys Val Asp Trp Ser Ile Ala Val Tyr 
    290                 295                 300


Thr Arg Gly Ala Glu Lys Leu Arg Ala Ala Glu Arg Phe Ala Lys Glu 
305                 310                 315                 320


Arg Arg Leu Arg Ile Trp Arg Asp Tyr Val Ala Pro Thr Ala Asn Leu 
                325                 330                 335


Asp Gln Lys Asp Lys Gln Phe Val Ala Lys Val Met Gln Val Leu Asn 
            340                 345                 350


Ala Asp Ala Ile Val Val Lys Leu Asn Ser Gly Asp Tyr Lys Thr Ile 
        355                 360                 365


His Leu Ser Ser Ile Arg Pro Pro Arg Leu Glu Gly Glu Asn Thr Gln 
    370                 375                 380


Asp Lys Asn Lys Lys Leu Arg Pro Leu Tyr Asp Ile Pro Tyr Met Phe 
385                 390                 395                 400


Glu Ala Arg Glu Phe Leu Arg Lys Lys Leu Ile Gly Lys Lys Val Asn 
                405                 410                 415


Val Thr Val Asp Tyr Ile Arg Pro Ala Ser Pro Ala Thr Glu Thr Val 
            420                 425                 430


Pro Ala Phe Ser Glu Arg Thr Cys Ala Thr Val Thr Ile Gly Gly Ile 
        435                 440                 445


Asn Ile Ala Glu Ala Leu Val Ser Lys Gly Leu Ala Thr Val Ile Arg 
    450                 455                 460


Tyr Arg Gln Asp Asp Asp Gln Arg Ser Ser His Tyr Asp Glu Leu Leu 
465                 470                 475                 480


Ala Ala Glu Ala Arg Ala Ile Lys Asn Gly Lys Gly Leu His Ser Lys 
                485                 490                 495


Lys Glu Val Pro Ile His Arg Val Ala Asp Ile Ser Gly Asp Thr Gln 
            500                 505                 510


Lys Ala Lys Gln Phe Leu Pro Phe Leu Gln Arg Ala Gly Arg Ser Glu 
        515                 520                 525


Ala Val Val Glu Tyr Val Phe Ser Gly Ser Arg Leu Lys Leu Tyr Leu 
    530                 535                 540


Pro Lys Glu Thr Cys Leu Ile Thr Phe Leu Leu Ala Gly Ile Glu Cys 
545                 550                 555                 560


Pro Arg Gly Ala Arg Asn Leu Pro Gly Leu Val Gln Glu Gly Glu Pro 
                565                 570                 575


Phe Ser Glu Glu Ala Thr Leu Phe Thr Lys Glu Leu Val Leu Gln Arg 
            580                 585                 590


Glu Val Glu Val Glu Val Glu Ser Met Asp Lys Ala Gly Asn Phe Ile 
        595                 600                 605


Gly Trp Leu His Ile Asp Gly Ala Asn Leu Ser Val Leu Leu Val Glu 
    610                 615                 620


His Ala Leu Ser Lys Val His Phe Thr Ala Glu Arg Ser Ser Tyr Tyr 
625                 630                 635                 640


Lys Ser Leu Leu Ser Ala Glu Glu Ala Ala Lys Gln Lys Lys Glu Lys 
                645                 650                 655


Val Trp Ala His Tyr Glu Glu Gln Pro Val Glu Glu Val Met Pro Val 
            660                 665                 670


Leu Glu Glu Lys Glu Arg Ser Ala Ser Tyr Lys Pro Val Phe Val Thr 
        675                 680                 685


Glu Ile Thr Asp Asp Leu His Phe Tyr Val Gln Asp Val Glu Thr Gly 
    690                 695                 700


Thr Gln Leu Glu Lys Leu Met Glu Asn Met Arg Asn Asp Ile Ala Ser 
705                 710                 715                 720


His Pro Pro Val Glu Gly Ser Tyr Ala Pro Arg Arg Gly Glu Phe Cys 
                725                 730                 735


Ile Ala Lys Phe Val Asp Gly Glu Trp Tyr Arg Ala Arg Val Glu Lys 
            740                 745                 750


Val Glu Ser Pro Ala Lys Ile His Val Phe Tyr Ile Asp Tyr Gly Asn 
        755                 760                 765


Arg Glu Val Leu Pro Ser Thr Arg Leu Gly Thr Leu Ser Pro Ala Phe 
    770                 775                 780


Ser Thr Arg Val Leu Pro Ala Gln Ala Thr Glu Tyr Ala Phe Ala Phe 
785                 790                 795                 800


Ile Gln Val Pro Gln Asp Asp Asp Ala Arg Thr Asp Ala Val Asp Ser 
                805                 810                 815


Val Val Arg Asp Ile Gln Asn Thr Gln Cys Leu Leu Asn Val Glu His 
            820                 825                 830


Leu Ser Ala Gly Cys Pro His Val Thr Leu Gln Phe Ala Asp Ser Lys 
        835                 840                 845


Gly Asp Val Gly Leu Gly Leu Val Lys Glu Gly Leu Val Met Val Glu 
    850                 855                 860


Val Arg Lys Glu Lys Gln Phe Gln Lys Val Ile Thr Glu Tyr Leu Asn 
865                 870                 875                 880


Ala Gln Glu Ser Ala Lys Ser Ala Arg Leu Asn Leu Trp Arg Tyr Gly 
                885                 890                 895


Asp Phe Arg Ala Asp Asp Ala Asp Glu Phe Gly Tyr Ser Arg 
            900                 905                 910


<210>  5416
<211>  3704
<212>  DNA
<213>  Homo sapiens

<400>  5416
aattgggcgg agggcggtgg cgctctggca cgcttgcgcg gcgagtagaa cgtgtggcgg     60

cggcggagat cgcgtctctt tcgctccgtg tcccgctgct gctcctgtga gcgcccggcg    120

agtccgtccc gtccaccgtc cgcagctggt agccagcctg cccctcgcct cgactccctt    180

tcaccaacac cgacacccac attgacacct ccagtccggc cagccgctcc actcgttgcc    240

tttgcatctc cacacatggc gtcctccgcg cagagcggcg gctcctccgg gggacccgcg    300

gtccccaccg tgcagcgggg catcatcaag atggtcctct cagggtgcgc catcattgtc    360

cgaggtcagc ctcgtggtgg gcctcctcct gagcggcaga tcaacctcag caacattcgt    420

gctggaaatc ttgctcgccg ggcagccgcc acacaacctg atgcaaagga tacccctgat    480

gagccctggg catttccagc tcgagagttc cttcgaaaga agctgattgg gaaggaagtc    540

tgtttcacga tagaaaacaa gactccccag gggcgagagt atggcatgat ctaccttgga    600

aaagatacca atggggaaaa cattgcagaa tcactggttg cagagggctt agccacccgg    660

agagaaggca tgagagctaa taatcctgag cagaaccggc tttcagaatg tgaagaacaa    720

gcaaaggcag ccaagaaagg gatgtggagt gaggggaacg gttcacatac tatccgggat    780

ctcaagtata ccattgaaaa cccaaggcac tttgtggact cacaccacca gaagcctgtt    840

aatgctatca tcgagcatgt gcgggacggc agtgtggtca gggccctgct cctcccagat    900

tactacctgg ttacagtcat gctgtcaggc atcaagtgcc caacttttcg acgggaagca    960

gatggcagtg aaactccaga gccttttgct gcagaagcca aatttttcac tgagtcgcga   1020

ctgcttcaga gagatgttca gatcattctg gagagctgcc acaaccagaa cattctgggt   1080

accatccttc atccaaatgg caacatcaca gagctcctcc tgaaggaagg tttcgcacgc   1140

tgtgtggact ggtcgattgc agtttacacc cggggcgcag aaaagctgag ggcggcagag   1200

aggtttgcca aagagcgcag gctgagaata tggagagact atgtggctcc cacagctaat   1260

ttggaccaaa aggacaagca gtttgttgcc aaggtgatgc aggttctgaa tgctgatgcc   1320

attgttgtga agctgaactc aggcgattac aagacgattc acctgtccag catccgacca   1380

ccgaggctgg agggggagaa cacccaggat aagaacaaga aactgcgtcc cctgtatgac   1440

attccttaca tgtttgaggc ccgggaattt cttcgaaaaa agcttattgg gaagaaggtc   1500

aatgtgacgg tggactacat tagaccagcc agcccagcca cagagacagt gcctgccttt   1560

tcagagcgta cctgtgccac tgtcaccatt ggaggaataa acattgctga ggctcttgtc   1620

agcaaaggtc tagccacagt gatcagatac cggcaggatg atgaccagag atcatcacac   1680

tacgatgaac tgcttgctgc agaggccaga gctattaaga atggcaaagg attgcatagc   1740

aagaaggaag tgcctatcca ccgtgttgca gatatatctg gggataccca aaaagcaaag   1800

cagttcctgc cttttcttca gcgggcaggt cgttctgaag ctgtggtgga atacgtcttc   1860

agtggttctc gtctcaaact ctatttgcca aaggaaactt gccttatcac cttcttgctt   1920

gcaggcattg aatgccccag aggagcccga aacctcccag gcttggtgca ggaaggagag   1980

cccttcagcg aggaagctac acttttcacc aaggaactgg tgctgcagcg agaggtggag   2040

gtggaggtgg agagcatgga caaggccggc aactttatcg gctggctgca catcgacggt   2100

gccaacctgt ccgtcctgct ggtggagcac gcgctctcca aggtccactt caccgccgaa   2160

cgcagctcct actacaagtc cctgctgtct gccgaggagg ccgcaaagca gaagaaagag   2220

aaggtctggg cccactatga ggagcagccc gtggaggagg tgatgccagt gctggaggag   2280

aaggagcgat ctgctagcta caagcccgtg tttgtgactg agatcactga tgacctgcac   2340

ttctacgtgc aggatgtgga gaccggcacc cagttggaga agctgatgga gaacatgcgc   2400

aatgacattg ccagtcaccc ccctgtagag ggctcctatg ccccccgcag gggagagttc   2460

tgcattgcca aatttgtaga tggagaatgg taccgtgccc gagtagagaa agtcgagtct   2520

cctgccaaaa tacatgtctt ctacattgac tacggcaaca gagaggtcct gccatccacc   2580

cgcctgggta ccctatcacc tgccttcagc actcgggtgc tgccagctca agccacggag   2640

tatgccttcg ccttcatcca ggtgccccaa gatgatgatg cccgcacgga cgccgtggac   2700

agcgtagttc gggatatcca gaacactcag tgcctgctca acgtggaaca cctgagtgcc   2760

ggctgccccc atgtcaccct gcagtttgca gattccaagg gcgatgtggg gctgggcttg   2820

gtgaaggaag ggctggtcat ggtggaggtg cgcaaggaga aacagttcca gaaagtgatc   2880

acagaatacc tgaatgccca agagtcagcc aagagcgcca ggctgaacct gtggcgctat   2940

ggagactttc gagctgatga tgcagacgaa tttggctaca gccgctaagg aggggatcgg   3000

gtttggcccc cagccccgct cacgccagtc cctcttcctc tgccgggagg gtgttttcaa   3060

ctccaaaccc cagagagggg ttgtagattg ggtccagctt tgcttcagtg tgtggaaatg   3120

tctcgtgggg tggcatcggg gctgcggggt ggggacccca aggctttctg gggcagaccc   3180

ttgtcctctg ggatgatggg cactgctatc cacagtctct gccagttggt tttatttgga   3240

ggtttgtggg ctttttttaa aaaaaaaaag tcctcaaatc aggaagaaac atcaaagact   3300

atgtcctagt ggagggagta atcctaacac ccaggctggc cgccagctgg cacctgcctc   3360

tatcccagac tgccctcgtc ccagctctct gtccaactgt tgattatgtg atttttctga   3420

tacgtccatt ctcaaatgcc agtgtgttca catcttcgct ctggccagcc cattctgtat   3480

ttaaagcttt tgaggcccaa taaaatagta cgtgctgtct gcagccctta ttgatcacag   3540

tgtggtccag agcatggagt cttggcagct tcacccagga ggagacctgg acacttgaat   3600

gacccccaag atagtcatcc aaatgcctgg acattctccc tagaaataga gccagctggg   3660

gaaagcaagg cagatcttca gagtctgagc aagcaactcc tgga                    3704


<210>  5417
<211>  910
<212>  PRT
<213>  Homo sapiens

<400>  5417

Met Ala Ser Ser Ala Gln Ser Gly Gly Ser Ser Gly Gly Pro Ala Val 
1               5                   10                  15


Pro Thr Val Gln Arg Gly Ile Ile Lys Met Val Leu Ser Gly Cys Ala 
            20                  25                  30


Ile Ile Val Arg Gly Gln Pro Arg Gly Gly Pro Pro Pro Glu Arg Gln 
        35                  40                  45


Ile Asn Leu Ser Asn Ile Arg Ala Gly Asn Leu Ala Arg Arg Ala Ala 
    50                  55                  60


Ala Thr Gln Pro Asp Ala Lys Asp Thr Pro Asp Glu Pro Trp Ala Phe 
65                  70                  75                  80


Pro Ala Arg Glu Phe Leu Arg Lys Lys Leu Ile Gly Lys Glu Val Cys 
                85                  90                  95


Phe Thr Ile Glu Asn Lys Thr Pro Gln Gly Arg Glu Tyr Gly Met Ile 
            100                 105                 110


Tyr Leu Gly Lys Asp Thr Asn Gly Glu Asn Ile Ala Glu Ser Leu Val 
        115                 120                 125


Ala Glu Gly Leu Ala Thr Arg Arg Glu Gly Met Arg Ala Asn Asn Pro 
    130                 135                 140


Glu Gln Asn Arg Leu Ser Glu Cys Glu Glu Gln Ala Lys Ala Ala Lys 
145                 150                 155                 160


Lys Gly Met Trp Ser Glu Gly Asn Gly Ser His Thr Ile Arg Asp Leu 
                165                 170                 175


Lys Tyr Thr Ile Glu Asn Pro Arg His Phe Val Asp Ser His His Gln 
            180                 185                 190


Lys Pro Val Asn Ala Ile Ile Glu His Val Arg Asp Gly Ser Val Val 
        195                 200                 205


Arg Ala Leu Leu Leu Pro Asp Tyr Tyr Leu Val Thr Val Met Leu Ser 
    210                 215                 220


Gly Ile Lys Cys Pro Thr Phe Arg Arg Glu Ala Asp Gly Ser Glu Thr 
225                 230                 235                 240


Pro Glu Pro Phe Ala Ala Glu Ala Lys Phe Phe Thr Glu Ser Arg Leu 
                245                 250                 255


Leu Gln Arg Asp Val Gln Ile Ile Leu Glu Ser Cys His Asn Gln Asn 
            260                 265                 270


Ile Leu Gly Thr Ile Leu His Pro Asn Gly Asn Ile Thr Glu Leu Leu 
        275                 280                 285


Leu Lys Glu Gly Phe Ala Arg Cys Val Asp Trp Ser Ile Ala Val Tyr 
    290                 295                 300


Thr Arg Gly Ala Glu Lys Leu Arg Ala Ala Glu Arg Phe Ala Lys Glu 
305                 310                 315                 320


Arg Arg Leu Arg Ile Trp Arg Asp Tyr Val Ala Pro Thr Ala Asn Leu 
                325                 330                 335


Asp Gln Lys Asp Lys Gln Phe Val Ala Lys Val Met Gln Val Leu Asn 
            340                 345                 350


Ala Asp Ala Ile Val Val Lys Leu Asn Ser Gly Asp Tyr Lys Thr Ile 
        355                 360                 365


His Leu Ser Ser Ile Arg Pro Pro Arg Leu Glu Gly Glu Asn Thr Gln 
    370                 375                 380


Asp Lys Asn Lys Lys Leu Arg Pro Leu Tyr Asp Ile Pro Tyr Met Phe 
385                 390                 395                 400


Glu Ala Arg Glu Phe Leu Arg Lys Lys Leu Ile Gly Lys Lys Val Asn 
                405                 410                 415


Val Thr Val Asp Tyr Ile Arg Pro Ala Ser Pro Ala Thr Glu Thr Val 
            420                 425                 430


Pro Ala Phe Ser Glu Arg Thr Cys Ala Thr Val Thr Ile Gly Gly Ile 
        435                 440                 445


Asn Ile Ala Glu Ala Leu Val Ser Lys Gly Leu Ala Thr Val Ile Arg 
    450                 455                 460


Tyr Arg Gln Asp Asp Asp Gln Arg Ser Ser His Tyr Asp Glu Leu Leu 
465                 470                 475                 480


Ala Ala Glu Ala Arg Ala Ile Lys Asn Gly Lys Gly Leu His Ser Lys 
                485                 490                 495


Lys Glu Val Pro Ile His Arg Val Ala Asp Ile Ser Gly Asp Thr Gln 
            500                 505                 510


Lys Ala Lys Gln Phe Leu Pro Phe Leu Gln Arg Ala Gly Arg Ser Glu 
        515                 520                 525


Ala Val Val Glu Tyr Val Phe Ser Gly Ser Arg Leu Lys Leu Tyr Leu 
    530                 535                 540


Pro Lys Glu Thr Cys Leu Ile Thr Phe Leu Leu Ala Gly Ile Glu Cys 
545                 550                 555                 560


Pro Arg Gly Ala Arg Asn Leu Pro Gly Leu Val Gln Glu Gly Glu Pro 
                565                 570                 575


Phe Ser Glu Glu Ala Thr Leu Phe Thr Lys Glu Leu Val Leu Gln Arg 
            580                 585                 590


Glu Val Glu Val Glu Val Glu Ser Met Asp Lys Ala Gly Asn Phe Ile 
        595                 600                 605


Gly Trp Leu His Ile Asp Gly Ala Asn Leu Ser Val Leu Leu Val Glu 
    610                 615                 620


His Ala Leu Ser Lys Val His Phe Thr Ala Glu Arg Ser Ser Tyr Tyr 
625                 630                 635                 640


Lys Ser Leu Leu Ser Ala Glu Glu Ala Ala Lys Gln Lys Lys Glu Lys 
                645                 650                 655


Val Trp Ala His Tyr Glu Glu Gln Pro Val Glu Glu Val Met Pro Val 
            660                 665                 670


Leu Glu Glu Lys Glu Arg Ser Ala Ser Tyr Lys Pro Val Phe Val Thr 
        675                 680                 685


Glu Ile Thr Asp Asp Leu His Phe Tyr Val Gln Asp Val Glu Thr Gly 
    690                 695                 700


Thr Gln Leu Glu Lys Leu Met Glu Asn Met Arg Asn Asp Ile Ala Ser 
705                 710                 715                 720


His Pro Pro Val Glu Gly Ser Tyr Ala Pro Arg Arg Gly Glu Phe Cys 
                725                 730                 735


Ile Ala Lys Phe Val Asp Gly Glu Trp Tyr Arg Ala Arg Val Glu Lys 
            740                 745                 750


Val Glu Ser Pro Ala Lys Ile His Val Phe Tyr Ile Asp Tyr Gly Asn 
        755                 760                 765


Arg Glu Val Leu Pro Ser Thr Arg Leu Gly Thr Leu Ser Pro Ala Phe 
    770                 775                 780


Ser Thr Arg Val Leu Pro Ala Gln Ala Thr Glu Tyr Ala Phe Ala Phe 
785                 790                 795                 800


Ile Gln Val Pro Gln Asp Asp Asp Ala Arg Thr Asp Ala Val Asp Ser 
                805                 810                 815


Val Val Arg Asp Ile Gln Asn Thr Gln Cys Leu Leu Asn Val Glu His 
            820                 825                 830


Leu Ser Ala Gly Cys Pro His Val Thr Leu Gln Phe Ala Asp Ser Lys 
        835                 840                 845


Gly Asp Val Gly Leu Gly Leu Val Lys Glu Gly Leu Val Met Val Glu 
    850                 855                 860


Val Arg Lys Glu Lys Gln Phe Gln Lys Val Ile Thr Glu Tyr Leu Asn 
865                 870                 875                 880


Ala Gln Glu Ser Ala Lys Ser Ala Arg Leu Asn Leu Trp Arg Tyr Gly 
                885                 890                 895


Asp Phe Arg Ala Asp Asp Ala Asp Glu Phe Gly Tyr Ser Arg 
            900                 905                 910


<210>  5418
<211>  451
<212>  DNA
<213>  Homo sapiens

<400>  5418
attgcagaat cactggttgc agagggctta gccacccgga gagaaggcat gagagctaat     60

aagtaagtac ccaaggcttt ctggggcaga cccttgtcct ctgggatgat gggcactgct    120

atccacagtc tctgccagtt ggttttattt ggaggtttgt gggctttttt taaaaaaaaa    180

aagtcctcaa atcaggaaga aacatcaaag actatgtcct agtggaggga gtaatcctaa    240

cacccaggct ggccgccagc tggcacctgc ctctatccca gactgccctc gtcccagctc    300

tctgtccaac tgttgattat gtgatttttc tgatacgtcc attctcaaat gccagtgtgt    360

tcacatcttc gctctggcca gcccattctg tatttaaagc ttttgaggcc caataaaata    420

gtacgtgctg tctgcagccc ttattgatca c                                   451


<210>  5419
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  5419

Met Met Gly Thr Ala Ile His Ser Leu Cys Gln Leu Val Leu Phe Gly 
1               5                   10                  15


Gly Leu Trp Ala Phe Phe Lys Lys Lys Lys Ser Ser Asn Gln Glu Glu 
            20                  25                  30


Thr Ser Lys Thr Met Ser 
        35


<210>  5420
<211>  617
<212>  DNA
<213>  Homo sapiens

<400>  5420
attgcagaat cactggttgc agagggctta gccacccgga gagaaggcat gagagctaat     60

aagtaagtac ccaaggcttt ctggggcaga cccttgtcct ctgggatgat gggcactgct    120

atccacagtc tctgccagtt ggttttattt ggaggtttgt gggctttttt taaaaaaaaa    180

aagtcctcaa atcaggaaga aacatcaaag actatgtcct agtggaggga gtaatcctaa    240

cacccaggct ggccgccagc tggcacctgc ctctatccca gactgccctc gtcccagctc    300

tctgtccaac tgttgattat gtgatttttc tgatacgtcc attctcaaat gccagtgtgt    360

tcacatcttc gctctggcca gcccattctg tatttaaagc ttttgaggcc caataaaata    420

gtacgtgctg tctgcagccc ttattgatca cagtgtggtc cagagcatgg agtcttggca    480

gcttcaccca ggaggagacc tggacacttg aatgaccccc aagatagtca tccaaatgcc    540

tggacattct ccctagaaat agagccagct ggggaaagca aggcagatct tcagagtctg    600

agcaagcaac tcctgga                                                   617


<210>  5421
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  5421

Met Met Gly Thr Ala Ile His Ser Leu Cys Gln Leu Val Leu Phe Gly 
1               5                   10                  15


Gly Leu Trp Ala Phe Phe Lys Lys Lys Lys Ser Ser Asn Gln Glu Glu 
            20                  25                  30


Thr Ser Lys Thr Met Ser 
        35


<210>  5422
<211>  502
<212>  DNA
<213>  Homo sapiens

<400>  5422
aaacattgct gaggctcttg tcagcaaagg tctagccaca gtgatcagat accggcagga     60

tgatgaccag agatcatcac actacgatga actgcttgct gcagaggcca gagctattaa    120

gaatggcaaa ggattgcata gcaagaagga agtgcctatc caccgtgttg cagatatatc    180

tggggtgagt cgagtccctg aatcaagctg tgtggctcag aggctcaaga gcgtgtctgc    240

atatttgctg aaggacttca gcttatgtat tttctctagc tcgctccttt tcaggcactg    300

actgtgactt ttccccaccc cggggcatct acttaggtat ctatagggag cctgttttat    360

tatctggaaa agcagaatta acttcattct ttttctttac ctgaactgtt tctatgttgc    420

tttttcattt ttaattactg tattttgagt ttggaaggta gttcttcttg gttgtattaa    480

aataaaattg cctcttttta aa                                             502


<210>  5423
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  5423

Met Met Thr Arg Asp His His Thr Thr Met Asn Cys Leu Leu Gln Arg 
1               5                   10                  15


Pro Glu Leu Leu Arg Met Ala Lys Asp Cys Ile Ala Arg Arg Lys Cys 
            20                  25                  30


Leu Ser Thr Val Leu Gln Ile Tyr Leu Gly 
        35                  40


<210>  5424
<211>  1126
<212>  DNA
<213>  Homo sapiens

<400>  5424
tgttatgttg tgagccgtgg tattaatcag ccacccctca ctaggtgttg gggttccacc     60

acgcttcctc caccccccgt caccacagca gcgggtagta tttaggttga atattccaaa    120

tagtcaatta tgacagttaa tttcaaatga gatgacttcg aagtacacgt gaaaacaata    180

ctattttata tcacgactca tgccatccgt atgtgtaatc aaagccttct aagtcttgat    240

atgtccttac aaagacgaag gatagagtga atgtcaaaat ttgccaaaca ggagttactg    300

aaagtctgaa ggggaaagcc tagttaggtt ttatcttaga agtgattttt aaaacgaaac    360

acgcagataa gctcgagctt tctggagccg attcctaagg ccttgcaggt ggtaaggggg    420

tcgagaattg gctgaggttc ctcggaagtc cgcgccgatt cggagggcca cctctgactt    480

tctgatctgg ggtgcaaccc ccagtccctg tcccggtcga caaaggtttg cctgcaatga    540

gatttcattc tctacattta aaggacatcc tttctgagct gctgtgaata aatttggaat    600

ggtactgtat attttcatct aatggagaac tagctgtact ttgaataagg attgctgcac    660

tggacgactt tagaacatcc ctcacaatgt cgtcaacccg gagccagaac ccccacggcc    720

tgaagcagat tggcctggac cagatctggg acgacctcag agccggcatc cagcaggtgt    780

acacacggca gagcatggcc aagtccagat atatggagct ctacacgtat cctcctgcct    840

agcgcaggtt gattgcttag agttttgatt atttactagt atgacttatg aattattaga    900

attttatatt gttttctcct cccagttcat catgtaaaat aatcgcaggg ttcattttta    960

gccttaagtt tttgaacaga gtagaactgg ttcattttta gtcaaatgca gcactgggca   1020

gtacagtcac cactgggcac atgtggctgt ttacatttga aatattttaa agttccttag   1080

gcacactagc tgtgtgatta ataaataaaa catttctgtc atgtag                  1126


<210>  5425
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5425

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr Tyr 
        35                  40                  45


Pro Pro Ala 
    50


<210>  5426
<211>  696
<212>  DNA
<213>  Homo sapiens

<400>  5426
gcgacgacgg tttcccggct cccccgcccc ggacgccgat ggcggtgcgt tccggccctc     60

ccccaacagc ttctcccccg cggtcgccgg agccggtttg cctgcaatga gatttcattc    120

tctacattta aaggacatcc tttctgagct gctgtgaata aatttggaat ggtactgtat    180

attttcatct aatggagaac tagctgtact ttgaataagg attgctgcac tggacgactt    240

tagaacatcc ctcacaatgt cgtcaacccg gagccagaac ccccacggcc tgaagcagat    300

tggcctggac cagatctggg acgacctcag agccggcatc cagcaggtgt acacacggca    360

gagcatggcc aagtccagat atatggagct ctacacgtat cctcctgcct agcgcaggtt    420

gattgcttag agttttgatt atttactagt atgacttatg aattattaga attttatatt    480

gttttctcct cccagttcat catgtaaaat aatcgcaggg ttcattttta gccttaagtt    540

tttgaacaga gtagaactgg ttcattttta gtcaaatgca gcactgggca gtacagtcac    600

cactgggcac atgtggctgt ttacatttga aatattttaa agttccttag gcacactagc    660

tgtgtgatta ataaataaaa catttctgtc atgtag                              696


<210>  5427
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5427

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr Tyr 
        35                  40                  45


Pro Pro Ala 
    50


<210>  5428
<211>  3155
<212>  DNA
<213>  Homo sapiens

<400>  5428
ggcggcggcg gcgggaggag gagggccggg cgggcagggg aggaggagga ggcgggcgcc     60

gtgtcgcacg cagctccagg cggggcagcc ccggtagctg agggacgcag ctagaccttg    120

gcgggacggg gctttcgccg gggcccaggc ccagggacca ggcggaggcg tcgcgggagc    180

ctttggggca ccacagagat gcgggtttgc ctgcaatgag atttcattct ctacatttaa    240

aggacatcct ttctgagctg ctgtgaataa atttggaatg gtactgtata ttttcatcta    300

atggagaact agctgtactt tgaataagga ttgctgcact ggacgacttt agaacatccc    360

tcacaatgtc gtcaacccgg agccagaacc cccacggcct gaagcagatt ggcctggacc    420

agatctggga cgacctcaga gccggcatcc agcaggtgta cacacggcag agcatggcca    480

agtccagata tatggagctc tacactcatg tttataacta ctgtactagt gttcaccagt    540

caaaccaagc acgaggagct ggagttcctc cttctaagtc gaaaaagggg cagacacctg    600

gaggagctca gtttgttggc ctggaattat ataaacgact taaggaattt ttgaagaatt    660

acttgacaaa tcttcttaag gatggagaag atttgatgga tgagagtgta ctgaaattct    720

acactcaaca atgggaagat tatcgatttt caagcaaagt gctgaatgga atttgtgcct    780

acctcaatag acattgggtt cgccgtgaat gtgacgaagg acgaaaagga atatatgaaa    840

tctattcgct tgcattggtg acttggagag actgtctgtt caggccactg aataaacagg    900

taacaaatgc tgttttaaag ctgattgaaa aggaaaggaa tggtgaaacc atcaatacaa    960

gattgattag tggagttgta cagtcttacg tggaattggg gctgaatgaa gatgatgcat   1020

ttgcaaaggg ccctacgtta acagtgtata aagaatcctt tgaatctcaa tttttggctg   1080

acacagagag attttatacc agagagagta ctgaattctt gcagcagaac ccagttactg   1140

aatatatgaa aaaggcagag gctcgtctgc ttgaggaaca acgaagagtt caggtttacc   1200

ttcatgaaag cacacaagat gaattagcaa ggaaatgtga acaagtcctc attgaaaaac   1260

acttggaaat tttccacaca gaatttcaga atttattgga tgctgacaaa aatgaagatt   1320

tgggacgcat gtataatctt gtatctagaa tccaggatgg cctaggagaa ttgaaaaaac   1380

tgttggagac acacattcat aatcagggtc ttgcagccat tgaaaagtgt ggagaagctg   1440

ctttaaatga ccccaaaatg tatgtacaga cagtgcttga tgttcataaa aaatacaatg   1500

ccctggtaat gtctgcattc aacaatgacg ctggctttgt ggctgctctt gataaggctt   1560

gtggtcgctt cataaacaac aacgcggtta ccaagatggc ccaatcatcc agtaaatccc   1620

ctgagttgct ggctcgatac tgtgactcct tgttgaagaa aagttccaag aacccagagg   1680

aggcagaact agaagacaca ctcaatcaag tgatggttgt cttcaagtac atagaagaca   1740

aagacgtatt tcagaagttc tatgcgaaga tgctcgccaa gaggctcgtc caccagaaca   1800

gtgcaagtga cgatgccgaa gccagcatga tctccaagtt aaagcaagct tgcgggttcg   1860

agtacacctc taaacttcag cgcatgtttc aagacattgg cgtgagcaaa gatctgaacg   1920

agcaattcaa aaagcacttg acaaactcag aacccctaga cttggatttc agcattcaag   1980

tgctgagctc cgggtcctgg cccttccagc agtcttgtac atttgccttg ccgtcagagt   2040

tggaacgtag ttatcagcga ttcacagctt tctacgccag ccgccacagt ggccgaaaat   2100

tgacgtggtt atatcagttg tctaaaggag aattggtaac taactgcttc aaaaacagat   2160

atactttgca ggcgtcgaca ttccagatgg ctatcctgct tcagtacaac acggaagatg   2220

cctacactgt gcagcagctg accgacagca ctcaaattaa aatggacatt ttggcgcaag   2280

ttttacagat tttattaaag tcgaagctat tggtcttgga agatgaaaat gcaaatgttg   2340

atgaggtgga attgaagcca gataccttaa taaaattata tcttggttat aaaaataaga   2400

aattaagggt taacatcaat gtgccaatga aaaccgaaca gaagcaggaa caagaaacca   2460

cacacaaaaa catcgaggaa gaccgcaaac tactgattca ggcggccatc gtgagaatca   2520

tgaagatgag gaaggttctg aaacaccagc agttacttgg cgaggtcctc actcagctgt   2580

cctccaggtt caaacctcga gtccctgtga tcaagaaatg cattgacatt ctaattgaga   2640

aagaatattt ggagcgagtg gatggtgaaa aggacaccta cagttacttg gcttaaccct   2700

tctggaaggg tctgactgtg tgacccgcag caaatagttc atgttggaaa gaatgaaaac   2760

aactcaagtt catagcagcc agcctgccgc cattggacct cccttttaaa aactgagacc   2820

aagactccca tcagctggtc tcggatttac atcggaactg ctcaggattg atacatttca   2880

agtctgtaaa tacggacacc aacgccattt accctaattt aagaacagcg gggactgacc   2940

ctccgtgccg agggctgcat gctaccgcac taagtcaata catgggctcc ccgattcgca   3000

gctgtcgtct tggcagcact tgtcacgttg gcagcacttt gagagcaagt ctgagtggac   3060

ccacatgtaa cctgctatga aaaccatttg tatagtgtgt ttcatttttt aatgtgtgaa   3120

aataaagaaa attaaaggat ttctgtacaa gtcgc                              3155


<210>  5429
<211>  776
<212>  PRT
<213>  Homo sapiens

<400>  5429

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr His 
        35                  40                  45


Val Tyr Asn Tyr Cys Thr Ser Val His Gln Ser Asn Gln Ala Arg Gly 
    50                  55                  60


Ala Gly Val Pro Pro Ser Lys Ser Lys Lys Gly Gln Thr Pro Gly Gly 
65                  70                  75                  80


Ala Gln Phe Val Gly Leu Glu Leu Tyr Lys Arg Leu Lys Glu Phe Leu 
                85                  90                  95


Lys Asn Tyr Leu Thr Asn Leu Leu Lys Asp Gly Glu Asp Leu Met Asp 
            100                 105                 110


Glu Ser Val Leu Lys Phe Tyr Thr Gln Gln Trp Glu Asp Tyr Arg Phe 
        115                 120                 125


Ser Ser Lys Val Leu Asn Gly Ile Cys Ala Tyr Leu Asn Arg His Trp 
    130                 135                 140


Val Arg Arg Glu Cys Asp Glu Gly Arg Lys Gly Ile Tyr Glu Ile Tyr 
145                 150                 155                 160


Ser Leu Ala Leu Val Thr Trp Arg Asp Cys Leu Phe Arg Pro Leu Asn 
                165                 170                 175


Lys Gln Val Thr Asn Ala Val Leu Lys Leu Ile Glu Lys Glu Arg Asn 
            180                 185                 190


Gly Glu Thr Ile Asn Thr Arg Leu Ile Ser Gly Val Val Gln Ser Tyr 
        195                 200                 205


Val Glu Leu Gly Leu Asn Glu Asp Asp Ala Phe Ala Lys Gly Pro Thr 
    210                 215                 220


Leu Thr Val Tyr Lys Glu Ser Phe Glu Ser Gln Phe Leu Ala Asp Thr 
225                 230                 235                 240


Glu Arg Phe Tyr Thr Arg Glu Ser Thr Glu Phe Leu Gln Gln Asn Pro 
                245                 250                 255


Val Thr Glu Tyr Met Lys Lys Ala Glu Ala Arg Leu Leu Glu Glu Gln 
            260                 265                 270


Arg Arg Val Gln Val Tyr Leu His Glu Ser Thr Gln Asp Glu Leu Ala 
        275                 280                 285


Arg Lys Cys Glu Gln Val Leu Ile Glu Lys His Leu Glu Ile Phe His 
    290                 295                 300


Thr Glu Phe Gln Asn Leu Leu Asp Ala Asp Lys Asn Glu Asp Leu Gly 
305                 310                 315                 320


Arg Met Tyr Asn Leu Val Ser Arg Ile Gln Asp Gly Leu Gly Glu Leu 
                325                 330                 335


Lys Lys Leu Leu Glu Thr His Ile His Asn Gln Gly Leu Ala Ala Ile 
            340                 345                 350


Glu Lys Cys Gly Glu Ala Ala Leu Asn Asp Pro Lys Met Tyr Val Gln 
        355                 360                 365


Thr Val Leu Asp Val His Lys Lys Tyr Asn Ala Leu Val Met Ser Ala 
    370                 375                 380


Phe Asn Asn Asp Ala Gly Phe Val Ala Ala Leu Asp Lys Ala Cys Gly 
385                 390                 395                 400


Arg Phe Ile Asn Asn Asn Ala Val Thr Lys Met Ala Gln Ser Ser Ser 
                405                 410                 415


Lys Ser Pro Glu Leu Leu Ala Arg Tyr Cys Asp Ser Leu Leu Lys Lys 
            420                 425                 430


Ser Ser Lys Asn Pro Glu Glu Ala Glu Leu Glu Asp Thr Leu Asn Gln 
        435                 440                 445


Val Met Val Val Phe Lys Tyr Ile Glu Asp Lys Asp Val Phe Gln Lys 
    450                 455                 460


Phe Tyr Ala Lys Met Leu Ala Lys Arg Leu Val His Gln Asn Ser Ala 
465                 470                 475                 480


Ser Asp Asp Ala Glu Ala Ser Met Ile Ser Lys Leu Lys Gln Ala Cys 
                485                 490                 495


Gly Phe Glu Tyr Thr Ser Lys Leu Gln Arg Met Phe Gln Asp Ile Gly 
            500                 505                 510


Val Ser Lys Asp Leu Asn Glu Gln Phe Lys Lys His Leu Thr Asn Ser 
        515                 520                 525


Glu Pro Leu Asp Leu Asp Phe Ser Ile Gln Val Leu Ser Ser Gly Ser 
    530                 535                 540


Trp Pro Phe Gln Gln Ser Cys Thr Phe Ala Leu Pro Ser Glu Leu Glu 
545                 550                 555                 560


Arg Ser Tyr Gln Arg Phe Thr Ala Phe Tyr Ala Ser Arg His Ser Gly 
                565                 570                 575


Arg Lys Leu Thr Trp Leu Tyr Gln Leu Ser Lys Gly Glu Leu Val Thr 
            580                 585                 590


Asn Cys Phe Lys Asn Arg Tyr Thr Leu Gln Ala Ser Thr Phe Gln Met 
        595                 600                 605


Ala Ile Leu Leu Gln Tyr Asn Thr Glu Asp Ala Tyr Thr Val Gln Gln 
    610                 615                 620


Leu Thr Asp Ser Thr Gln Ile Lys Met Asp Ile Leu Ala Gln Val Leu 
625                 630                 635                 640


Gln Ile Leu Leu Lys Ser Lys Leu Leu Val Leu Glu Asp Glu Asn Ala 
                645                 650                 655


Asn Val Asp Glu Val Glu Leu Lys Pro Asp Thr Leu Ile Lys Leu Tyr 
            660                 665                 670


Leu Gly Tyr Lys Asn Lys Lys Leu Arg Val Asn Ile Asn Val Pro Met 
        675                 680                 685


Lys Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile Glu 
    690                 695                 700


Glu Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met Lys 
705                 710                 715                 720


Met Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu Thr 
                725                 730                 735


Gln Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Lys Cys 
            740                 745                 750


Ile Asp Ile Leu Ile Glu Lys Glu Tyr Leu Glu Arg Val Asp Gly Glu 
        755                 760                 765


Lys Asp Thr Tyr Ser Tyr Leu Ala 
    770                 775


<210>  5430
<211>  3226
<212>  DNA
<213>  Homo sapiens

<400>  5430
ggcggcggcg gcgggaggag gagggccggg cgggcagggg aggaggagga ggcgggcgcc     60

gtgtcgcacg cagctccagg cggggcagcc ccggtagctg agggacgcag ctagaccttg    120

gcgggacggg gctttcgccg gggcccaggc ccagggacca ggcggaggcg tcgcgggagc    180

ctttggggca ccacagagat gcgggtttgc ctgcaatgag atttcattct ctacatttaa    240

aggacatcct ttctgagctg ctgtgaataa atttggaatg gtactgtata ttttcatcta    300

atggagaact agctgtactt tgaataagga ttgctgcact ggacgacttt agaacatccc    360

tcacaatgtc gtcaacccgg agccagaacc cccacggcct gaagcagatt ggcctggacc    420

agatctggga cgacctcaga gccggcatcc agcaggtgta cacacggcag agcatggcca    480

agtccagata tatggagctc tacactcatg tttataacta ctgtactagt gttcaccagt    540

caaaccaagc acgaggagct ggagttcctc cttctaagtc gaaaaagggg cagacacctg    600

gaggagctca gtttgttggc ctggaattat ataaacgact taaggaattt ttgaagaatt    660

acttgacaaa tcttcttaag gatggagaag atttgatgga tgagagtgta ctgaaattct    720

acactcaaca atgggaagat tatcgatttt caagcaaagt gctgaatgga atttgtgcct    780

acctcaatag acattgggtt cgccgtgaat gtgacgaagg acgaaaagga atatatgaaa    840

tctattcgct tgcattggtg acttggagag actgtctgtt caggccactg aataaacagg    900

taacaaatgc tgttttaaag ctgattgaaa aggaaaggaa tggtgaaacc atcaatacaa    960

gattgattag tggagttgta cagtcttacg tggaattggg gctgaatgaa gatgatgcat   1020

ttgcaaaggg ccctacgtta acagtgtata aagaatcctt tgaatctcaa tttttggctg   1080

acacagagag attttatacc agagagagta ctgaattctt gcagcagaac ccagttactg   1140

aatatatgaa aaaggcagag gctcgtctgc ttgaggaaca acgaagagtt caggtttacc   1200

ttcatgaaag cacacaagat gaattagcaa ggaaatgtga acaagtcctc attgaaaaac   1260

acttggaaat tttccacaca gaatttcaga atttattgga tgctgacaaa aatgaagatt   1320

tgggacgcat gtataatctt gtatctagaa tccaggatgg cctaggagaa ttgaaaaaac   1380

tgttggagac acacattcat aatcagggtc ttgcagccat tgaaaagtgt ggagaagctg   1440

ctttaaatga ccccaaaatg tatgtacaga cagtgcttga tgttcataaa aaatacaatg   1500

ccctggtaat gtctgcattc aacaatgacg ctggctttgt ggctgctctt gataaggctt   1560

gtggtcgctt cataaacaac aacgcggtta ccaagatggc ccaatcatcc agtaaatccc   1620

ctgagttgct ggctcgatac tgtgactcct tgttgaagaa aagttccaag aacccagagg   1680

aggcagaact agaagacaca ctcaatcaag tgatggttgt cttcaagtac atagaagaca   1740

aagacgtatt tcagaagttc tatgcgaaga tgctcgccaa gaggctcgtc caccagaaca   1800

gtgcaagtga cgatgccgaa gccagcatga tctccaagtt aaagcaagct tgcgggttcg   1860

agtacacctc taaacttcag cgcatgtttc aagacattgg cgtgagcaaa gatctgaacg   1920

agcaattcaa aaagcacttg acaaactcag aacccctaga cttggatttc agcattcaag   1980

tgctgagctc cgggtcctgg cccttccagc agtcttgtac atttgccttg ccgtcagagt   2040

tggaacgtag ttatcagcga ttcacagctt tctacgccag ccgccacagt ggccgaaaat   2100

tgacgtggtt atatcagttg tctaaaggag aattggtaac taactgcttc aaaaacagat   2160

atactttgca ggcgtcgaca ttccagatgg ctatcctgct tcagtacaac acggaagatg   2220

cctacactgt gcagcagctg accgacagca ctcaaattaa aatggacatt ttggcgcaag   2280

ttttacagat tttattaaag tcgaagctat tggtcttgga agatgaaaat gcaaatgttg   2340

atgaggtgga attgaagcca gataccttaa taaaattata tcttggttat aaaaataaga   2400

aattaagggt taacatcaat gtgccaatga aaaccgaaca gaagcaggaa caagaaacca   2460

cacacaaaaa catcgaggaa gaccgcaaac tactgattca ggcggccatc gtgagaatca   2520

tgaagatgag gaaggttctg aaacaccagc agttacttgg cgaggtcctc actcagctgt   2580

cctccaggtt caaacctcga gtccctgtga tcaagaaatg cattgacatt ctaattgaga   2640

aagaatattt ggagcgagtg gatggtgaaa aggacaccta cagttacttg gcttaaccct   2700

tctggaaggg tctgactgtg tgacccgcag caaatagttc atgttggaaa gaatgaaaac   2760

aactcaagtt catagcagcc agcctgccgc cattggacct cccttttaaa aactgagacc   2820

aagactccca tcagctggtc tcggatttac atcggaactg ctcaggattg atacatttca   2880

agtctgtaaa tacggacacc aacgccattt accctaattt aagaacagcg gggactgacc   2940

ctccgtgccg agggctgcat gctaccgcac taagtcaata catgggctcc ccgattcgca   3000

gctgtcgtct tggcagcact tgtcacgttg gcagcacttt gagagcaagt ctgagtggac   3060

ccacatgtaa cctgctatga aaaccatttg tatagtgtgt ttcatttttt aatgtgtgaa   3120

aataaagaaa attaaaggat ttctgtacaa gtcgcattgg gttttgtttt aagttttact   3180

aatttctata tgtaaataaa agatataatg attgtgcaaa tttata                  3226


<210>  5431
<211>  776
<212>  PRT
<213>  Homo sapiens

<400>  5431

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr His 
        35                  40                  45


Val Tyr Asn Tyr Cys Thr Ser Val His Gln Ser Asn Gln Ala Arg Gly 
    50                  55                  60


Ala Gly Val Pro Pro Ser Lys Ser Lys Lys Gly Gln Thr Pro Gly Gly 
65                  70                  75                  80


Ala Gln Phe Val Gly Leu Glu Leu Tyr Lys Arg Leu Lys Glu Phe Leu 
                85                  90                  95


Lys Asn Tyr Leu Thr Asn Leu Leu Lys Asp Gly Glu Asp Leu Met Asp 
            100                 105                 110


Glu Ser Val Leu Lys Phe Tyr Thr Gln Gln Trp Glu Asp Tyr Arg Phe 
        115                 120                 125


Ser Ser Lys Val Leu Asn Gly Ile Cys Ala Tyr Leu Asn Arg His Trp 
    130                 135                 140


Val Arg Arg Glu Cys Asp Glu Gly Arg Lys Gly Ile Tyr Glu Ile Tyr 
145                 150                 155                 160


Ser Leu Ala Leu Val Thr Trp Arg Asp Cys Leu Phe Arg Pro Leu Asn 
                165                 170                 175


Lys Gln Val Thr Asn Ala Val Leu Lys Leu Ile Glu Lys Glu Arg Asn 
            180                 185                 190


Gly Glu Thr Ile Asn Thr Arg Leu Ile Ser Gly Val Val Gln Ser Tyr 
        195                 200                 205


Val Glu Leu Gly Leu Asn Glu Asp Asp Ala Phe Ala Lys Gly Pro Thr 
    210                 215                 220


Leu Thr Val Tyr Lys Glu Ser Phe Glu Ser Gln Phe Leu Ala Asp Thr 
225                 230                 235                 240


Glu Arg Phe Tyr Thr Arg Glu Ser Thr Glu Phe Leu Gln Gln Asn Pro 
                245                 250                 255


Val Thr Glu Tyr Met Lys Lys Ala Glu Ala Arg Leu Leu Glu Glu Gln 
            260                 265                 270


Arg Arg Val Gln Val Tyr Leu His Glu Ser Thr Gln Asp Glu Leu Ala 
        275                 280                 285


Arg Lys Cys Glu Gln Val Leu Ile Glu Lys His Leu Glu Ile Phe His 
    290                 295                 300


Thr Glu Phe Gln Asn Leu Leu Asp Ala Asp Lys Asn Glu Asp Leu Gly 
305                 310                 315                 320


Arg Met Tyr Asn Leu Val Ser Arg Ile Gln Asp Gly Leu Gly Glu Leu 
                325                 330                 335


Lys Lys Leu Leu Glu Thr His Ile His Asn Gln Gly Leu Ala Ala Ile 
            340                 345                 350


Glu Lys Cys Gly Glu Ala Ala Leu Asn Asp Pro Lys Met Tyr Val Gln 
        355                 360                 365


Thr Val Leu Asp Val His Lys Lys Tyr Asn Ala Leu Val Met Ser Ala 
    370                 375                 380


Phe Asn Asn Asp Ala Gly Phe Val Ala Ala Leu Asp Lys Ala Cys Gly 
385                 390                 395                 400


Arg Phe Ile Asn Asn Asn Ala Val Thr Lys Met Ala Gln Ser Ser Ser 
                405                 410                 415


Lys Ser Pro Glu Leu Leu Ala Arg Tyr Cys Asp Ser Leu Leu Lys Lys 
            420                 425                 430


Ser Ser Lys Asn Pro Glu Glu Ala Glu Leu Glu Asp Thr Leu Asn Gln 
        435                 440                 445


Val Met Val Val Phe Lys Tyr Ile Glu Asp Lys Asp Val Phe Gln Lys 
    450                 455                 460


Phe Tyr Ala Lys Met Leu Ala Lys Arg Leu Val His Gln Asn Ser Ala 
465                 470                 475                 480


Ser Asp Asp Ala Glu Ala Ser Met Ile Ser Lys Leu Lys Gln Ala Cys 
                485                 490                 495


Gly Phe Glu Tyr Thr Ser Lys Leu Gln Arg Met Phe Gln Asp Ile Gly 
            500                 505                 510


Val Ser Lys Asp Leu Asn Glu Gln Phe Lys Lys His Leu Thr Asn Ser 
        515                 520                 525


Glu Pro Leu Asp Leu Asp Phe Ser Ile Gln Val Leu Ser Ser Gly Ser 
    530                 535                 540


Trp Pro Phe Gln Gln Ser Cys Thr Phe Ala Leu Pro Ser Glu Leu Glu 
545                 550                 555                 560


Arg Ser Tyr Gln Arg Phe Thr Ala Phe Tyr Ala Ser Arg His Ser Gly 
                565                 570                 575


Arg Lys Leu Thr Trp Leu Tyr Gln Leu Ser Lys Gly Glu Leu Val Thr 
            580                 585                 590


Asn Cys Phe Lys Asn Arg Tyr Thr Leu Gln Ala Ser Thr Phe Gln Met 
        595                 600                 605


Ala Ile Leu Leu Gln Tyr Asn Thr Glu Asp Ala Tyr Thr Val Gln Gln 
    610                 615                 620


Leu Thr Asp Ser Thr Gln Ile Lys Met Asp Ile Leu Ala Gln Val Leu 
625                 630                 635                 640


Gln Ile Leu Leu Lys Ser Lys Leu Leu Val Leu Glu Asp Glu Asn Ala 
                645                 650                 655


Asn Val Asp Glu Val Glu Leu Lys Pro Asp Thr Leu Ile Lys Leu Tyr 
            660                 665                 670


Leu Gly Tyr Lys Asn Lys Lys Leu Arg Val Asn Ile Asn Val Pro Met 
        675                 680                 685


Lys Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile Glu 
    690                 695                 700


Glu Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met Lys 
705                 710                 715                 720


Met Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu Thr 
                725                 730                 735


Gln Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Lys Cys 
            740                 745                 750


Ile Asp Ile Leu Ile Glu Lys Glu Tyr Leu Glu Arg Val Asp Gly Glu 
        755                 760                 765


Lys Asp Thr Tyr Ser Tyr Leu Ala 
    770                 775


<210>  5432
<211>  2956
<212>  DNA
<213>  Homo sapiens

<400>  5432
gggaggagga ggaggcgggc gccgtgtcgc acgcagctcc aggcggggca gccccggtag     60

ctgagggacg cagctagacc ttggcgggac ggggctttcg ccggggccca ggcccaggga    120

ccaggcggag gcgtcgcggg agcctttggg gcaccacaga gatgcgggtt tgcctgcaat    180

gagatttcat tctctacatt taaaggacat cctttctgag ctgctgtgaa taaatttgga    240

atggtactgt atattttcat ctaatggaga actagctgta ctttgaataa ggattgctgc    300

actggacgac tttagaacat ccctcacaat gtcgtcaacc cggagccaga acccccacgg    360

cctgaatcca gatatatgga gctctacact catgtttata actactgtac tagtgttcac    420

cagtcaaacc aagcacgagg agctggagtt cctccttcta agtcgaaaaa ggggcagaca    480

cctggaggag ctcagtttgt tggcctggaa ttatataaac gacttaagga atttttgaag    540

aattacttga caaatcttct taaggatgga gaagatttga tggatgagag tgtactgaaa    600

ttctacactc aacaatggga agattatcga ttttcaagca aagtgctgaa tggaatttgt    660

gcctacctca atagacattg ggttcgccgt gaatgtgacg aaggacgaaa aggaatatat    720

gaaatctatt cgcttgcatt ggtgacttgg agagactgtc tgttcaggcc actgaataaa    780

caggtaacaa atgctgtttt aaagctgatt gaaaaggaaa ggaatggtga aaccatcaat    840

acaagattga ttagtggagt tgtacagtct tacgtggaat tggggctgaa tgaagatgat    900

gcatttgcaa agggccctac gttaacagtg tataaagaat cctttgaatc tcaatttttg    960

gctgacacag agagatttta taccagagag agtactgaat tcttgcagca gaacccagtt   1020

actgaatata tgaaaaaggc agaggctcgt ctgcttgagg aacaacgaag agttcaggtt   1080

taccttcatg aaagcacaca agatgaatta gcaaggaaat gtgaacaagt cctcattgaa   1140

aaacacttgg aaattttcca cacagaattt cagaatttat tggatgctga caaaaatgaa   1200

gatttgggac gcatgtataa tcttgtatct agaatccagg atggcctagg agaattgaaa   1260

aaactgttgg agacacacat tcataatcag ggtcttgcag ccattgaaaa gtgtggagaa   1320

gctgctttaa atgaccccaa aatgtatgta cagacagtgc ttgatgttca taaaaaatac   1380

aatgccctgg taatgtctgc attcaacaat gacgctggct ttgtggctgc tcttgataag   1440

gcttgtggtc gcttcataaa caacaacgcg gttaccaaga tggcccaatc atccagtaaa   1500

tcccctgagt tgctggctcg atactgtgac tccttgttga agaaaagttc caagaaccca   1560

gaggaggcag aactagaaga cacactcaat caagtgatgg ttgtcttcaa gtacatagaa   1620

gacaaagacg tatttcagaa gttctatgcg aagatgctcg ccaagaggct cgtccaccag   1680

aacagtgcaa gtgacgatgc cgaagccagc atgatctcca agttaaagca agcttgcggg   1740

ttcgagtaca cctctaaact tcagcgcatg tttcaagaca ttggcgtgag caaagatctg   1800

aacgagcaat tcaaaaagca cttgacaaac tcagaacccc tagacttgga tttcagcatt   1860

caagtgctga gctccgggtc ctggcccttc cagcagtctt gtacatttgc cttgccgtca   1920

gagttggaac gtagttatca gcgattcaca gctttctacg ccagccgcca cagtggccga   1980

aaattgacgt ggttatatca gttgtctaaa ggagaattgg taactaactg cttcaaaaac   2040

agatatactt tgcaggcgtc gacattccag atggctatcc tgcttcagta caacacggaa   2100

gatgcctaca ctgtgcagca gctgaccgac agcactcaaa ttaaaatgga cattttggcg   2160

caagttttac agattttatt aaagtcgaag ctattgtaag aaattaaggg ttaacatcaa   2220

tgtgccaatg aaaaccgaac agaagcagga acaagaaacc acacacaaaa acatcgagga   2280

agaccgcaaa ctactgattc aggcggccat cgtgagaatc atgaagatga ggaaggttct   2340

gaaacaccag cagttacttg gcgaggtcct cactcagctg tcctccaggt tcaaacctcg   2400

agtccctgtg atcaagaaat gcattgacat tctaattgag aaagaatatt tggagcgagt   2460

ggatggtgaa aaggacacct acagttactt ggcttaaccc ttctggaagg gtctgactgt   2520

gtgacccgca gcaaatagtt catgttggaa agaatgaaaa caactcaagt tcatagcagc   2580

cagcctgccg ccattggacc tcccttttaa aaactgagac caagactccc atcagctggt   2640

ctcggattta catcggaact gctcaggatt gatacatttc aagtctgtaa atacggacac   2700

caacgccatt taccctaatt taagaacagc ggggactgac cctccgtgcc gagggctgca   2760

tgctaccgca ctaagtcaat acatgggctc cccgattcgc agctgtcgtc ttggcagcac   2820

ttgtcacgtt ggcagcactt tgagagcaag tctgagtgga cccacatgta acctgctatg   2880

aaaaccattt gtatagtgtg tttcattttt taatgtgtga aaataaagaa aattaaagga   2940

tttctgtaca agtcgc                                                   2956


<210>  5433
<211>  607
<212>  PRT
<213>  Homo sapiens

<400>  5433

Met Glu Leu Tyr Thr His Val Tyr Asn Tyr Cys Thr Ser Val His Gln 
1               5                   10                  15


Ser Asn Gln Ala Arg Gly Ala Gly Val Pro Pro Ser Lys Ser Lys Lys 
            20                  25                  30


Gly Gln Thr Pro Gly Gly Ala Gln Phe Val Gly Leu Glu Leu Tyr Lys 
        35                  40                  45


Arg Leu Lys Glu Phe Leu Lys Asn Tyr Leu Thr Asn Leu Leu Lys Asp 
    50                  55                  60


Gly Glu Asp Leu Met Asp Glu Ser Val Leu Lys Phe Tyr Thr Gln Gln 
65                  70                  75                  80


Trp Glu Asp Tyr Arg Phe Ser Ser Lys Val Leu Asn Gly Ile Cys Ala 
                85                  90                  95


Tyr Leu Asn Arg His Trp Val Arg Arg Glu Cys Asp Glu Gly Arg Lys 
            100                 105                 110


Gly Ile Tyr Glu Ile Tyr Ser Leu Ala Leu Val Thr Trp Arg Asp Cys 
        115                 120                 125


Leu Phe Arg Pro Leu Asn Lys Gln Val Thr Asn Ala Val Leu Lys Leu 
    130                 135                 140


Ile Glu Lys Glu Arg Asn Gly Glu Thr Ile Asn Thr Arg Leu Ile Ser 
145                 150                 155                 160


Gly Val Val Gln Ser Tyr Val Glu Leu Gly Leu Asn Glu Asp Asp Ala 
                165                 170                 175


Phe Ala Lys Gly Pro Thr Leu Thr Val Tyr Lys Glu Ser Phe Glu Ser 
            180                 185                 190


Gln Phe Leu Ala Asp Thr Glu Arg Phe Tyr Thr Arg Glu Ser Thr Glu 
        195                 200                 205


Phe Leu Gln Gln Asn Pro Val Thr Glu Tyr Met Lys Lys Ala Glu Ala 
    210                 215                 220


Arg Leu Leu Glu Glu Gln Arg Arg Val Gln Val Tyr Leu His Glu Ser 
225                 230                 235                 240


Thr Gln Asp Glu Leu Ala Arg Lys Cys Glu Gln Val Leu Ile Glu Lys 
                245                 250                 255


His Leu Glu Ile Phe His Thr Glu Phe Gln Asn Leu Leu Asp Ala Asp 
            260                 265                 270


Lys Asn Glu Asp Leu Gly Arg Met Tyr Asn Leu Val Ser Arg Ile Gln 
        275                 280                 285


Asp Gly Leu Gly Glu Leu Lys Lys Leu Leu Glu Thr His Ile His Asn 
    290                 295                 300


Gln Gly Leu Ala Ala Ile Glu Lys Cys Gly Glu Ala Ala Leu Asn Asp 
305                 310                 315                 320


Pro Lys Met Tyr Val Gln Thr Val Leu Asp Val His Lys Lys Tyr Asn 
                325                 330                 335


Ala Leu Val Met Ser Ala Phe Asn Asn Asp Ala Gly Phe Val Ala Ala 
            340                 345                 350


Leu Asp Lys Ala Cys Gly Arg Phe Ile Asn Asn Asn Ala Val Thr Lys 
        355                 360                 365


Met Ala Gln Ser Ser Ser Lys Ser Pro Glu Leu Leu Ala Arg Tyr Cys 
    370                 375                 380


Asp Ser Leu Leu Lys Lys Ser Ser Lys Asn Pro Glu Glu Ala Glu Leu 
385                 390                 395                 400


Glu Asp Thr Leu Asn Gln Val Met Val Val Phe Lys Tyr Ile Glu Asp 
                405                 410                 415


Lys Asp Val Phe Gln Lys Phe Tyr Ala Lys Met Leu Ala Lys Arg Leu 
            420                 425                 430


Val His Gln Asn Ser Ala Ser Asp Asp Ala Glu Ala Ser Met Ile Ser 
        435                 440                 445


Lys Leu Lys Gln Ala Cys Gly Phe Glu Tyr Thr Ser Lys Leu Gln Arg 
    450                 455                 460


Met Phe Gln Asp Ile Gly Val Ser Lys Asp Leu Asn Glu Gln Phe Lys 
465                 470                 475                 480


Lys His Leu Thr Asn Ser Glu Pro Leu Asp Leu Asp Phe Ser Ile Gln 
                485                 490                 495


Val Leu Ser Ser Gly Ser Trp Pro Phe Gln Gln Ser Cys Thr Phe Ala 
            500                 505                 510


Leu Pro Ser Glu Leu Glu Arg Ser Tyr Gln Arg Phe Thr Ala Phe Tyr 
        515                 520                 525


Ala Ser Arg His Ser Gly Arg Lys Leu Thr Trp Leu Tyr Gln Leu Ser 
    530                 535                 540


Lys Gly Glu Leu Val Thr Asn Cys Phe Lys Asn Arg Tyr Thr Leu Gln 
545                 550                 555                 560


Ala Ser Thr Phe Gln Met Ala Ile Leu Leu Gln Tyr Asn Thr Glu Asp 
                565                 570                 575


Ala Tyr Thr Val Gln Gln Leu Thr Asp Ser Thr Gln Ile Lys Met Asp 
            580                 585                 590


Ile Leu Ala Gln Val Leu Gln Ile Leu Leu Lys Ser Lys Leu Leu 
        595                 600                 605


<210>  5434
<211>  3027
<212>  DNA
<213>  Homo sapiens

<400>  5434
gggaggagga ggaggcgggc gccgtgtcgc acgcagctcc aggcggggca gccccggtag     60

ctgagggacg cagctagacc ttggcgggac ggggctttcg ccggggccca ggcccaggga    120

ccaggcggag gcgtcgcggg agcctttggg gcaccacaga gatgcgggtt tgcctgcaat    180

gagatttcat tctctacatt taaaggacat cctttctgag ctgctgtgaa taaatttgga    240

atggtactgt atattttcat ctaatggaga actagctgta ctttgaataa ggattgctgc    300

actggacgac tttagaacat ccctcacaat gtcgtcaacc cggagccaga acccccacgg    360

cctgaatcca gatatatgga gctctacact catgtttata actactgtac tagtgttcac    420

cagtcaaacc aagcacgagg agctggagtt cctccttcta agtcgaaaaa ggggcagaca    480

cctggaggag ctcagtttgt tggcctggaa ttatataaac gacttaagga atttttgaag    540

aattacttga caaatcttct taaggatgga gaagatttga tggatgagag tgtactgaaa    600

ttctacactc aacaatggga agattatcga ttttcaagca aagtgctgaa tggaatttgt    660

gcctacctca atagacattg ggttcgccgt gaatgtgacg aaggacgaaa aggaatatat    720

gaaatctatt cgcttgcatt ggtgacttgg agagactgtc tgttcaggcc actgaataaa    780

caggtaacaa atgctgtttt aaagctgatt gaaaaggaaa ggaatggtga aaccatcaat    840

acaagattga ttagtggagt tgtacagtct tacgtggaat tggggctgaa tgaagatgat    900

gcatttgcaa agggccctac gttaacagtg tataaagaat cctttgaatc tcaatttttg    960

gctgacacag agagatttta taccagagag agtactgaat tcttgcagca gaacccagtt   1020

actgaatata tgaaaaaggc agaggctcgt ctgcttgagg aacaacgaag agttcaggtt   1080

taccttcatg aaagcacaca agatgaatta gcaaggaaat gtgaacaagt cctcattgaa   1140

aaacacttgg aaattttcca cacagaattt cagaatttat tggatgctga caaaaatgaa   1200

gatttgggac gcatgtataa tcttgtatct agaatccagg atggcctagg agaattgaaa   1260

aaactgttgg agacacacat tcataatcag ggtcttgcag ccattgaaaa gtgtggagaa   1320

gctgctttaa atgaccccaa aatgtatgta cagacagtgc ttgatgttca taaaaaatac   1380

aatgccctgg taatgtctgc attcaacaat gacgctggct ttgtggctgc tcttgataag   1440

gcttgtggtc gcttcataaa caacaacgcg gttaccaaga tggcccaatc atccagtaaa   1500

tcccctgagt tgctggctcg atactgtgac tccttgttga agaaaagttc caagaaccca   1560

gaggaggcag aactagaaga cacactcaat caagtgatgg ttgtcttcaa gtacatagaa   1620

gacaaagacg tatttcagaa gttctatgcg aagatgctcg ccaagaggct cgtccaccag   1680

aacagtgcaa gtgacgatgc cgaagccagc atgatctcca agttaaagca agcttgcggg   1740

ttcgagtaca cctctaaact tcagcgcatg tttcaagaca ttggcgtgag caaagatctg   1800

aacgagcaat tcaaaaagca cttgacaaac tcagaacccc tagacttgga tttcagcatt   1860

caagtgctga gctccgggtc ctggcccttc cagcagtctt gtacatttgc cttgccgtca   1920

gagttggaac gtagttatca gcgattcaca gctttctacg ccagccgcca cagtggccga   1980

aaattgacgt ggttatatca gttgtctaaa ggagaattgg taactaactg cttcaaaaac   2040

agatatactt tgcaggcgtc gacattccag atggctatcc tgcttcagta caacacggaa   2100

gatgcctaca ctgtgcagca gctgaccgac agcactcaaa ttaaaatgga cattttggcg   2160

caagttttac agattttatt aaagtcgaag ctattgtaag aaattaaggg ttaacatcaa   2220

tgtgccaatg aaaaccgaac agaagcagga acaagaaacc acacacaaaa acatcgagga   2280

agaccgcaaa ctactgattc aggcggccat cgtgagaatc atgaagatga ggaaggttct   2340

gaaacaccag cagttacttg gcgaggtcct cactcagctg tcctccaggt tcaaacctcg   2400

agtccctgtg atcaagaaat gcattgacat tctaattgag aaagaatatt tggagcgagt   2460

ggatggtgaa aaggacacct acagttactt ggcttaaccc ttctggaagg gtctgactgt   2520

gtgacccgca gcaaatagtt catgttggaa agaatgaaaa caactcaagt tcatagcagc   2580

cagcctgccg ccattggacc tcccttttaa aaactgagac caagactccc atcagctggt   2640

ctcggattta catcggaact gctcaggatt gatacatttc aagtctgtaa atacggacac   2700

caacgccatt taccctaatt taagaacagc ggggactgac cctccgtgcc gagggctgca   2760

tgctaccgca ctaagtcaat acatgggctc cccgattcgc agctgtcgtc ttggcagcac   2820

ttgtcacgtt ggcagcactt tgagagcaag tctgagtgga cccacatgta acctgctatg   2880

aaaaccattt gtatagtgtg tttcattttt taatgtgtga aaataaagaa aattaaagga   2940

tttctgtaca agtcgcattg ggttttgttt taagttttac taatttctat atgtaaataa   3000

aagatataat gattgtgcaa atttata                                       3027


<210>  5435
<211>  607
<212>  PRT
<213>  Homo sapiens

<400>  5435

Met Glu Leu Tyr Thr His Val Tyr Asn Tyr Cys Thr Ser Val His Gln 
1               5                   10                  15


Ser Asn Gln Ala Arg Gly Ala Gly Val Pro Pro Ser Lys Ser Lys Lys 
            20                  25                  30


Gly Gln Thr Pro Gly Gly Ala Gln Phe Val Gly Leu Glu Leu Tyr Lys 
        35                  40                  45


Arg Leu Lys Glu Phe Leu Lys Asn Tyr Leu Thr Asn Leu Leu Lys Asp 
    50                  55                  60


Gly Glu Asp Leu Met Asp Glu Ser Val Leu Lys Phe Tyr Thr Gln Gln 
65                  70                  75                  80


Trp Glu Asp Tyr Arg Phe Ser Ser Lys Val Leu Asn Gly Ile Cys Ala 
                85                  90                  95


Tyr Leu Asn Arg His Trp Val Arg Arg Glu Cys Asp Glu Gly Arg Lys 
            100                 105                 110


Gly Ile Tyr Glu Ile Tyr Ser Leu Ala Leu Val Thr Trp Arg Asp Cys 
        115                 120                 125


Leu Phe Arg Pro Leu Asn Lys Gln Val Thr Asn Ala Val Leu Lys Leu 
    130                 135                 140


Ile Glu Lys Glu Arg Asn Gly Glu Thr Ile Asn Thr Arg Leu Ile Ser 
145                 150                 155                 160


Gly Val Val Gln Ser Tyr Val Glu Leu Gly Leu Asn Glu Asp Asp Ala 
                165                 170                 175


Phe Ala Lys Gly Pro Thr Leu Thr Val Tyr Lys Glu Ser Phe Glu Ser 
            180                 185                 190


Gln Phe Leu Ala Asp Thr Glu Arg Phe Tyr Thr Arg Glu Ser Thr Glu 
        195                 200                 205


Phe Leu Gln Gln Asn Pro Val Thr Glu Tyr Met Lys Lys Ala Glu Ala 
    210                 215                 220


Arg Leu Leu Glu Glu Gln Arg Arg Val Gln Val Tyr Leu His Glu Ser 
225                 230                 235                 240


Thr Gln Asp Glu Leu Ala Arg Lys Cys Glu Gln Val Leu Ile Glu Lys 
                245                 250                 255


His Leu Glu Ile Phe His Thr Glu Phe Gln Asn Leu Leu Asp Ala Asp 
            260                 265                 270


Lys Asn Glu Asp Leu Gly Arg Met Tyr Asn Leu Val Ser Arg Ile Gln 
        275                 280                 285


Asp Gly Leu Gly Glu Leu Lys Lys Leu Leu Glu Thr His Ile His Asn 
    290                 295                 300


Gln Gly Leu Ala Ala Ile Glu Lys Cys Gly Glu Ala Ala Leu Asn Asp 
305                 310                 315                 320


Pro Lys Met Tyr Val Gln Thr Val Leu Asp Val His Lys Lys Tyr Asn 
                325                 330                 335


Ala Leu Val Met Ser Ala Phe Asn Asn Asp Ala Gly Phe Val Ala Ala 
            340                 345                 350


Leu Asp Lys Ala Cys Gly Arg Phe Ile Asn Asn Asn Ala Val Thr Lys 
        355                 360                 365


Met Ala Gln Ser Ser Ser Lys Ser Pro Glu Leu Leu Ala Arg Tyr Cys 
    370                 375                 380


Asp Ser Leu Leu Lys Lys Ser Ser Lys Asn Pro Glu Glu Ala Glu Leu 
385                 390                 395                 400


Glu Asp Thr Leu Asn Gln Val Met Val Val Phe Lys Tyr Ile Glu Asp 
                405                 410                 415


Lys Asp Val Phe Gln Lys Phe Tyr Ala Lys Met Leu Ala Lys Arg Leu 
            420                 425                 430


Val His Gln Asn Ser Ala Ser Asp Asp Ala Glu Ala Ser Met Ile Ser 
        435                 440                 445


Lys Leu Lys Gln Ala Cys Gly Phe Glu Tyr Thr Ser Lys Leu Gln Arg 
    450                 455                 460


Met Phe Gln Asp Ile Gly Val Ser Lys Asp Leu Asn Glu Gln Phe Lys 
465                 470                 475                 480


Lys His Leu Thr Asn Ser Glu Pro Leu Asp Leu Asp Phe Ser Ile Gln 
                485                 490                 495


Val Leu Ser Ser Gly Ser Trp Pro Phe Gln Gln Ser Cys Thr Phe Ala 
            500                 505                 510


Leu Pro Ser Glu Leu Glu Arg Ser Tyr Gln Arg Phe Thr Ala Phe Tyr 
        515                 520                 525


Ala Ser Arg His Ser Gly Arg Lys Leu Thr Trp Leu Tyr Gln Leu Ser 
    530                 535                 540


Lys Gly Glu Leu Val Thr Asn Cys Phe Lys Asn Arg Tyr Thr Leu Gln 
545                 550                 555                 560


Ala Ser Thr Phe Gln Met Ala Ile Leu Leu Gln Tyr Asn Thr Glu Asp 
                565                 570                 575


Ala Tyr Thr Val Gln Gln Leu Thr Asp Ser Thr Gln Ile Lys Met Asp 
            580                 585                 590


Ile Leu Ala Gln Val Leu Gln Ile Leu Leu Lys Ser Lys Leu Leu 
        595                 600                 605


<210>  5436
<211>  1767
<212>  DNA
<213>  Homo sapiens

<400>  5436
aggaggcggg cgccgtgtcg cacgcagctc caggcggggc agccccggta gctgagggac     60

gcagctagac cttggcggga cggggctttc gccggggccc aggcccaggg accaggcgga    120

ggcgtcgcgg gagcctttgg ggcaccacag agatgcgggt ttgcctgcaa tgagatttca    180

ttctctacat ttaaaggaca tcctttctga gctgctgtga ataaatttgg aatggtactg    240

tatattttca tctaatggag aactagctgt actttgaata aggattgctg cactggacga    300

ctttagaaca tccctcacaa tgtcgtcaac ccggagccag aacccccacg gcctgaagca    360

gattggcctg gaccagatct gggacgacct cagagccggc atccagcagg tgtacacacg    420

gcagagcatg gccaagtcca gatatatgga gctctacacg tatcctcctg cctagcgcag    480

gttgattgct tagagttttg attatttact agtatgactt atgaattatt agaattttat    540

attgttttct cctcccagtt catcatgtaa aataatcgca gggttcattt ttagccttaa    600

gtttttgaac agagtagaac tggttcattt ttagtcaaat gcagcactgg gcagtacagt    660

caccactggg cacatgtggc tgtttacatt tgaaatattt taaagttcct taggcacact    720

agctgtgtga ttaataaata aaacatttct gtcatgtaga aggttccgtt gggcaaagct    780

ggtctaaagc aaggtcctga ggttctcagc agatcatttg ttttacgtcc atttgtttat    840

atattgtcta tgactgcctt gtgttatggg aacagagtta agtagttgtg tcagaaacag    900

ttttgtccat gaagcctaaa atatttacta cctgcccttt tacaggaaaa gtttgtttac    960

ctgatcaaaa gggataggac atcgagcaaa agttttcctg ttatggccct atttttttgt   1020

gtttttgaga caaggtctcg ctctgtcacc caggctggag tgcagtggta tgatcacagc   1080

tcaccgcagc ctcaactacc tgcactcaag caatcctccc atctcagcct cccaagtagc   1140

tgggaccaca gacacgtgcc accacacctg gccaattttt tttttattgt ttatagagac   1200

agagtcttgc tatgttgccc gggctgtggc cctatttttt aaagtacagt atttaaaaag   1260

aattttattc ctttagtttt tggtccacga tgtgcatggg ggactgtgct gtgtgccaca   1320

aaggtgatga gggtggaaaa gatgcggctc ccactattcg tgtggttgga gatgcaccag   1380

ctaatttgga ggctttcttg attccataca aatatgacat tgaaattaga gttaagctca   1440

ctcaggagag aggagattgc cactgtttct aggactttaa agttgctgat tcaacggagc   1500

ttcaggttta aagtcttcag gtttgataga ctatatcagt tctatcaaac tagtttttgt   1560

gatattccag tatgttcttg catgttaata ttttagaatc ctaaaaaaaa tttaagtaga   1620

tataaaacta tgtcaatctc tgaattagca taaaatgtgt gtttgcatat ttatacatgt   1680

atatacactt acatatagaa tacttttaaa ataatagctt tattgagatg taattatgta   1740

ccataaaatt caacctttta aaaagta                                       1767


<210>  5437
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  5437

Met Ala Leu Phe Phe Cys Val Phe Glu Thr Arg Ser Arg Ser Val Thr 
1               5                   10                  15


Gln Ala Gly Val Gln Trp Tyr Asp His Ser Ser Pro Gln Pro Gln Leu 
            20                  25                  30


Pro Ala Leu Lys Gln Ser Ser His Leu Ser Leu Pro Ser Ser Trp Asp 
        35                  40                  45


His Arg His Val Pro Pro His Leu Ala Asn Phe Phe Phe Ile Val Tyr 
    50                  55                  60


Arg Asp Arg Val Leu Leu Cys Cys Pro Gly Cys Gly Pro Ile Phe 
65                  70                  75


<210>  5438
<211>  1236
<212>  DNA
<213>  Homo sapiens

<400>  5438
gcttcttccc ggcgctgctt tccggccgac gcgtgttccc ctgtgagctc tgggctcaag     60

cgcaggagca gccgcggagc cgggctctct cgctttccgg ttccctgccc gcggctctcg    120

ggttccccgc ctgcattgtt gcgaacgtgc agggcgctat tattgggtaa cagtcgccct    180

tttgccccgt tctcctggga gagcgggccg gggcatgcgc gcagggatgc tagcccggcg    240

gccgaaccgg acagagcccc ccggcgcccg cctatcgctc gctagtcggg ccgggccctg    300

cgctgcggcc tcggcgcgcc cccggtccca acgggagcgc gcgccctgac cctgagggta    360

gccgtgcgcc cgccaggccg ctgggacttg gggtccccag actcgggggt cgtcgctttt    420

ttttccctta agatctgaaa gacccccgtt tctgccaccc gtgcagtatt gtgtagcgca    480

gacataagat aagaaagaga ggaatgcttg tagacattcc ttgaaatgaa tccccaaagt    540

tagggttttc tccctggctg gctttgccaa aaagaggatt ctcttttccg attgggtcac    600

tcttggttgc ttctggttcg tagtaggggt tagtggtttg cctgcaatga gatttcattc    660

tctacattta aaggacatcc tttctgagct gctgtgaata aatttggaat ggtactgtat    720

attttcatct aatggagaac tagctgtact ttgaataagg attgctgcac tggacgactt    780

tagaacatcc ctcacaatgt cgtcaacccg gagccagaac ccccacggcc tgaagcagat    840

tggcctggac cagatctggg acgacctcag agccggcatc cagcaggtgt acacacggca    900

gagcatggcc aagtccagat atatggagct ctacacgtat cctcctgcct agcgcaggtt    960

gattgcttag agttttgatt atttactagt atgacttatg aattattaga attttatatt   1020

gttttctcct cccagttcat catgtaaaat aatcgcaggg ttcattttta gccttaagtt   1080

tttgaacaga gtagaactgg ttcattttta gtcaaatgca gcactgggca gtacagtcac   1140

cactgggcac atgtggctgt ttacatttga aatattttaa agttccttag gcacactagc   1200

tgtgtgatta ataaataaaa catttctgtc atgtag                             1236


<210>  5439
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5439

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr Tyr 
        35                  40                  45


Pro Pro Ala 
    50


<210>  5440
<211>  465
<212>  DNA
<213>  Homo sapiens

<400>  5440
ggtttgcctg caatgagatt tcattctcta catttaaagg acatcctttc tgagctgctg     60

tgaataaatt tggaatggta ctgtatattt tcatctaatg gagaactagc tgtactttga    120

ataaggattg ctgcactgga cgactttaga acatccctca caatgtcgtc aacccggagc    180

cagaaccccc acggcctgaa gcagattggc ctggaccaga tctgggacga cctcagagcc    240

ggcatccagc aggtgtacac acggcagagc atggccaagt ccagatatat ggagctctac    300

acgtatcctc ctgcctagcg cagaggaaag gccatgtgag gacacagtga gaaggtggcc    360

gtctgcaacc ctggaagaga gccctcacca gaaaccaacc ctgacagtac cttgagctcg    420

gacctctagt ctccagaact gtgagaaaat aaattcctgt tgttt                    465


<210>  5441
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5441

Met Ser Ser Thr Arg Ser Gln Asn Pro His Gly Leu Lys Gln Ile Gly 
1               5                   10                  15


Leu Asp Gln Ile Trp Asp Asp Leu Arg Ala Gly Ile Gln Gln Val Tyr 
            20                  25                  30


Thr Arg Gln Ser Met Ala Lys Ser Arg Tyr Met Glu Leu Tyr Thr Tyr 
        35                  40                  45


Pro Pro Ala 
    50


<210>  5442
<211>  355
<212>  DNA
<213>  Homo sapiens

<400>  5442
tgatcaaaag ggataggaca tcgagcaaaa gttttcctgt tatggcccta attttttaaa     60

gtacagtatt taaaaagaat tttattcctt tagtttttgg tccacgatgt gcatggggga    120

ctgtgctgtg tgccacaaag gtgatgaggg tggaaaagat gcggctccca ctattcgtgt    180

ggtctgtttc taggacttta aagttgctga ttcaacggag cttcaggttt aaagtcttca    240

ggtttgatag actatatcag ttctatcaaa ctagtttttg tgatattcca gtatgttctt    300

gctaaaatgt gtgtttgcat atttatacat gtatatacac ttacatatag aatac         355


<210>  5443
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  5443

Met Arg Val Glu Lys Met Arg Leu Pro Leu Phe Val Trp Ser Val Ser 
1               5                   10                  15


Arg Thr Leu Lys Leu Leu Ile Gln Arg Ser Phe Arg Phe Lys Val Phe 
            20                  25                  30


Arg Phe Asp Arg Leu Tyr Gln Phe Tyr Gln Thr Ser Phe Cys Asp Ile 
        35                  40                  45


Pro Val Cys Ser Cys 
    50


<210>  5444
<211>  584
<212>  DNA
<213>  Homo sapiens

<400>  5444
tgatcaaaag ggataggaca tcgagcaaaa gttttcctgt tatggcccta attttttaaa     60

gtacagtatt taaaaagaat tttattcctt tagtttttgg tccacgatgt gcatggggga    120

ctgtgctgtg tgccacaaag gtgatgaggg tggaaaagat gcggctccca ctattcgtgt    180

ggttggagat gcaccagcta atttggaggc tttcttgatt ccatacaaat atgacattga    240

aattagagtt aagctcactc aggagagagg agattgccac tgtttctagg actttaaagt    300

tgctgattca acggagcttc aggtttaaag tcttcaggtt tgatagacta tatcagttct    360

atcaaactag tttttgtgat attccagtat gttcttgcat gttaatattt tagaatccta    420

aaaaaaattt aagtagatat aaaactatgt caatctctga attagcataa aatgtgtgtt    480

tgcatattta tacatgtata tacacttaca tatagaatac ttttaaaata atagctttat    540

tgagatgtaa ttatgtacca taaaattcaa ccttttaaaa agta                     584


<210>  5445
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  5445

Met Cys Met Gly Asp Cys Ala Val Cys His Lys Gly Asp Glu Gly Gly 
1               5                   10                  15


Lys Asp Ala Ala Pro Thr Ile Arg Val Val Gly Asp Ala Pro Ala Asn 
            20                  25                  30


Leu Glu Ala Phe Leu Ile Pro Tyr Lys Tyr Asp Ile Glu Ile Arg Val 
        35                  40                  45


Lys Leu Thr Gln Glu Arg Gly Asp Cys His Cys Phe 
    50                  55                  60


<210>  5446
<211>  2799
<212>  DNA
<213>  Homo sapiens

<400>  5446
agtttctctc taaatttttg aacagtctga tttctgatga tgatttccat gtaatcactt     60

cagggcttat atttgtgtga ctcttggctt caagtagttt ttaatctaaa gtaccacatc    120

ttagtatctg cacagaagat gcattcattt cttagagtgg cagagacatt acctcaaaaa    180

gataaaatac cattctctga gggatcaaaa tgatgtaaag acatgttaac tgttaataac    240

gatgatgttg ttagggcact taaaaaggaa gtttgaaatg gaaatacgta ttacagagaa    300

aatggcagac atcagtggct gtttaaatat ggttgttgtt taccgtaaaa tcaaagaact    360

ttttcctttt tctttctgtt ttttgagaaa cggagtcttg ctctgttgcc caggctgaaa    420

tgcagtggca caatcatagc ttactatgtc ctttaactcc taggctcaag ccatcctccc    480

gcctcagcct cctgagtagc taggaaggac tacaggcgcg tgccacacct ggctaatttt    540

ttttttagag acagggtcgc actgtgttgc ccaggctggt ctcaaaatcc tggcctcgag    600

caatcctcct gcttcagcca cccaaagtgg ctgagccatc atgcccagcc ctcccttatt    660

ttcttaatcg cattttatta gagctggcat gtgaatttaa tttgccattt ttcagtttcc    720

tttaatttac atattaaaga attgtaacag ttctttacca atgaatcaaa accattcact    780

tgaattaatt ttctccaggc agaggctcgt ctgcttgagg aacaacgaag agttcaggtt    840

taccttcatg aaagcacaca agatgaatta gcaaggaaat gtgaacaagt cctcattgaa    900

aaacacttgg aaattttcca cacagaattt cagaatttat tggatgctga caaaaatgaa    960

gatttgggac gcatgtataa tcttgtatct agaatccagg atggcctagg agaattgaaa   1020

aaactgttgg agacacacat tcataatcag ggtcttgcag ccattgaaaa gtgtggagaa   1080

gctgctttaa atgaccccaa aatgtatgta cagacagtgc ttgatgttca taaaaaatac   1140

aatgccctgg taatgtctgc attcaacaat gacgctggct ttgtggctgc tcttgataag   1200

gcttgtggtc gcttcataaa caacaacgcg gttaccaaga tggcccaatc atccagtaaa   1260

tcccctgagt tgctggctcg atactgtgac tccttgttga agaaaagttc caagaaccca   1320

gaggaggcag aactagaaga cacactcaat caagtgatgg ttgtcttcaa gtacatagaa   1380

gacaaagacg tatttcagaa gttctatgcg aagatgctcg ccaagaggct cgtccaccag   1440

aacagtgcaa gtgacgatgc cgaagccagc atgatctcca agttaaagca agcttgcggg   1500

ttcgagtaca cctctaaact tcagcgcatg tttcaagaca ttggcgtgag caaagatctg   1560

aacgagcaat tcaaaaagca cttgacaaac tcagaacccc tagacttgga tttcagcatt   1620

caagtgctga gctccgggtc ctggcccttc cagcagtctt gtacatttgc cttgccgtca   1680

gagttggaac gtagttatca gcgattcaca gctttctacg ccagccgcca cagtggccga   1740

aaattgacgt ggttatatca gttgtctaaa ggagaattgg taactaactg cttcaaaaac   1800

agatatactt tgcaggcgtc gacattccag atggctatcc tgcttcagta caacacggaa   1860

gatgcctaca ctgtgcagca gctgaccgac agcactcaaa ttaaaatgga cattttggcg   1920

caagttttac agattttatt aaagtcgaag ctattggtct tggaagatga aaatgcaaat   1980

gttgatgagg tggaattgaa gccagatacc ttaataaaat tatatcttgg ttataaaaat   2040

aagaaattaa gggttaacat caatgtgcca atgaaaaccg aacagaagca ggaacaagaa   2100

accacacaca aaaacatcga ggaagaccgc aaactactga ttcaggcggc catcgtgaga   2160

atcatgaaga tgaggaaggt tctgaaacac cagcagttac ttggcgaggt cctcactcag   2220

ctgtcctcca ggttcaaacc tcgagtccct gtgatcaaga aatgcattga cattctaatt   2280

gagaaagaat atttggagcg agtggatggt gaaaaggaca cctacagtta cttggcttaa   2340

cccttctgga agggtctgac tgtgtgaccc gcagcaaata gttcatgttg gaaagaatga   2400

aaacaactca agttcatagc agccagcctg ccgccattgg acctcccttt taaaaactga   2460

gaccaagact cccatcagct ggtctcggat ttacatcgga actgctcagg attgatacat   2520

ttcaagtctg taaatacgga caccaacgcc atttacccta atttaagaac agcggggact   2580

gaccctccgt gccgagggct gcatgctacc gcactaagtc aatacatggg ctccccgatt   2640

cgcagctgtc gtcttggcag cacttgtcac gttggcagca ctttgagagc aagtctgagt   2700

ggacccacat gtaacctgct atgaaaacca tttgtatagt gtgtttcatt ttttaatgtg   2760

tgaaaataaa gaaaattaaa ggatttctgt acaagtcgc                          2799


<210>  5447
<211>  455
<212>  PRT
<213>  Homo sapiens

<400>  5447

Met Tyr Asn Leu Val Ser Arg Ile Gln Asp Gly Leu Gly Glu Leu Lys 
1               5                   10                  15


Lys Leu Leu Glu Thr His Ile His Asn Gln Gly Leu Ala Ala Ile Glu 
            20                  25                  30


Lys Cys Gly Glu Ala Ala Leu Asn Asp Pro Lys Met Tyr Val Gln Thr 
        35                  40                  45


Val Leu Asp Val His Lys Lys Tyr Asn Ala Leu Val Met Ser Ala Phe 
    50                  55                  60


Asn Asn Asp Ala Gly Phe Val Ala Ala Leu Asp Lys Ala Cys Gly Arg 
65                  70                  75                  80


Phe Ile Asn Asn Asn Ala Val Thr Lys Met Ala Gln Ser Ser Ser Lys 
                85                  90                  95


Ser Pro Glu Leu Leu Ala Arg Tyr Cys Asp Ser Leu Leu Lys Lys Ser 
            100                 105                 110


Ser Lys Asn Pro Glu Glu Ala Glu Leu Glu Asp Thr Leu Asn Gln Val 
        115                 120                 125


Met Val Val Phe Lys Tyr Ile Glu Asp Lys Asp Val Phe Gln Lys Phe 
    130                 135                 140


Tyr Ala Lys Met Leu Ala Lys Arg Leu Val His Gln Asn Ser Ala Ser 
145                 150                 155                 160


Asp Asp Ala Glu Ala Ser Met Ile Ser Lys Leu Lys Gln Ala Cys Gly 
                165                 170                 175


Phe Glu Tyr Thr Ser Lys Leu Gln Arg Met Phe Gln Asp Ile Gly Val 
            180                 185                 190


Ser Lys Asp Leu Asn Glu Gln Phe Lys Lys His Leu Thr Asn Ser Glu 
        195                 200                 205


Pro Leu Asp Leu Asp Phe Ser Ile Gln Val Leu Ser Ser Gly Ser Trp 
    210                 215                 220


Pro Phe Gln Gln Ser Cys Thr Phe Ala Leu Pro Ser Glu Leu Glu Arg 
225                 230                 235                 240


Ser Tyr Gln Arg Phe Thr Ala Phe Tyr Ala Ser Arg His Ser Gly Arg 
                245                 250                 255


Lys Leu Thr Trp Leu Tyr Gln Leu Ser Lys Gly Glu Leu Val Thr Asn 
            260                 265                 270


Cys Phe Lys Asn Arg Tyr Thr Leu Gln Ala Ser Thr Phe Gln Met Ala 
        275                 280                 285


Ile Leu Leu Gln Tyr Asn Thr Glu Asp Ala Tyr Thr Val Gln Gln Leu 
    290                 295                 300


Thr Asp Ser Thr Gln Ile Lys Met Asp Ile Leu Ala Gln Val Leu Gln 
305                 310                 315                 320


Ile Leu Leu Lys Ser Lys Leu Leu Val Leu Glu Asp Glu Asn Ala Asn 
                325                 330                 335


Val Asp Glu Val Glu Leu Lys Pro Asp Thr Leu Ile Lys Leu Tyr Leu 
            340                 345                 350


Gly Tyr Lys Asn Lys Lys Leu Arg Val Asn Ile Asn Val Pro Met Lys 
        355                 360                 365


Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile Glu Glu 
    370                 375                 380


Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met Lys Met 
385                 390                 395                 400


Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu Thr Gln 
                405                 410                 415


Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Lys Cys Ile 
            420                 425                 430


Asp Ile Leu Ile Glu Lys Glu Tyr Leu Glu Arg Val Asp Gly Glu Lys 
        435                 440                 445


Asp Thr Tyr Ser Tyr Leu Ala 
    450                 455


<210>  5448
<211>  2870
<212>  DNA
<213>  Homo sapiens

<400>  5448
agtttctctc taaatttttg aacagtctga tttctgatga tgatttccat gtaatcactt     60

cagggcttat atttgtgtga ctcttggctt caagtagttt ttaatctaaa gtaccacatc    120

ttagtatctg cacagaagat gcattcattt cttagagtgg cagagacatt acctcaaaaa    180

gataaaatac cattctctga gggatcaaaa tgatgtaaag acatgttaac tgttaataac    240

gatgatgttg ttagggcact taaaaaggaa gtttgaaatg gaaatacgta ttacagagaa    300

aatggcagac atcagtggct gtttaaatat ggttgttgtt taccgtaaaa tcaaagaact    360

ttttcctttt tctttctgtt ttttgagaaa cggagtcttg ctctgttgcc caggctgaaa    420

tgcagtggca caatcatagc ttactatgtc ctttaactcc taggctcaag ccatcctccc    480

gcctcagcct cctgagtagc taggaaggac tacaggcgcg tgccacacct ggctaatttt    540

ttttttagag acagggtcgc actgtgttgc ccaggctggt ctcaaaatcc tggcctcgag    600

caatcctcct gcttcagcca cccaaagtgg ctgagccatc atgcccagcc ctcccttatt    660

ttcttaatcg cattttatta gagctggcat gtgaatttaa tttgccattt ttcagtttcc    720

tttaatttac atattaaaga attgtaacag ttctttacca atgaatcaaa accattcact    780

tgaattaatt ttctccaggc agaggctcgt ctgcttgagg aacaacgaag agttcaggtt    840

taccttcatg aaagcacaca agatgaatta gcaaggaaat gtgaacaagt cctcattgaa    900

aaacacttgg aaattttcca cacagaattt cagaatttat tggatgctga caaaaatgaa    960

gatttgggac gcatgtataa tcttgtatct agaatccagg atggcctagg agaattgaaa   1020

aaactgttgg agacacacat tcataatcag ggtcttgcag ccattgaaaa gtgtggagaa   1080

gctgctttaa atgaccccaa aatgtatgta cagacagtgc ttgatgttca taaaaaatac   1140

aatgccctgg taatgtctgc attcaacaat gacgctggct ttgtggctgc tcttgataag   1200

gcttgtggtc gcttcataaa caacaacgcg gttaccaaga tggcccaatc atccagtaaa   1260

tcccctgagt tgctggctcg atactgtgac tccttgttga agaaaagttc caagaaccca   1320

gaggaggcag aactagaaga cacactcaat caagtgatgg ttgtcttcaa gtacatagaa   1380

gacaaagacg tatttcagaa gttctatgcg aagatgctcg ccaagaggct cgtccaccag   1440

aacagtgcaa gtgacgatgc cgaagccagc atgatctcca agttaaagca agcttgcggg   1500

ttcgagtaca cctctaaact tcagcgcatg tttcaagaca ttggcgtgag caaagatctg   1560

aacgagcaat tcaaaaagca cttgacaaac tcagaacccc tagacttgga tttcagcatt   1620

caagtgctga gctccgggtc ctggcccttc cagcagtctt gtacatttgc cttgccgtca   1680

gagttggaac gtagttatca gcgattcaca gctttctacg ccagccgcca cagtggccga   1740

aaattgacgt ggttatatca gttgtctaaa ggagaattgg taactaactg cttcaaaaac   1800

agatatactt tgcaggcgtc gacattccag atggctatcc tgcttcagta caacacggaa   1860

gatgcctaca ctgtgcagca gctgaccgac agcactcaaa ttaaaatgga cattttggcg   1920

caagttttac agattttatt aaagtcgaag ctattggtct tggaagatga aaatgcaaat   1980

gttgatgagg tggaattgaa gccagatacc ttaataaaat tatatcttgg ttataaaaat   2040

aagaaattaa gggttaacat caatgtgcca atgaaaaccg aacagaagca ggaacaagaa   2100

accacacaca aaaacatcga ggaagaccgc aaactactga ttcaggcggc catcgtgaga   2160

atcatgaaga tgaggaaggt tctgaaacac cagcagttac ttggcgaggt cctcactcag   2220

ctgtcctcca ggttcaaacc tcgagtccct gtgatcaaga aatgcattga cattctaatt   2280

gagaaagaat atttggagcg agtggatggt gaaaaggaca cctacagtta cttggcttaa   2340

cccttctgga agggtctgac tgtgtgaccc gcagcaaata gttcatgttg gaaagaatga   2400

aaacaactca agttcatagc agccagcctg ccgccattgg acctcccttt taaaaactga   2460

gaccaagact cccatcagct ggtctcggat ttacatcgga actgctcagg attgatacat   2520

ttcaagtctg taaatacgga caccaacgcc atttacccta atttaagaac agcggggact   2580

gaccctccgt gccgagggct gcatgctacc gcactaagtc aatacatggg ctccccgatt   2640

cgcagctgtc gtcttggcag cacttgtcac gttggcagca ctttgagagc aagtctgagt   2700

ggacccacat gtaacctgct atgaaaacca tttgtatagt gtgtttcatt ttttaatgtg   2760

tgaaaataaa gaaaattaaa ggatttctgt acaagtcgca ttgggttttg ttttaagttt   2820

tactaatttc tatatgtaaa taaaagatat aatgattgtg caaatttata              2870


<210>  5449
<211>  455
<212>  PRT
<213>  Homo sapiens

<400>  5449

Met Tyr Asn Leu Val Ser Arg Ile Gln Asp Gly Leu Gly Glu Leu Lys 
1               5                   10                  15


Lys Leu Leu Glu Thr His Ile His Asn Gln Gly Leu Ala Ala Ile Glu 
            20                  25                  30


Lys Cys Gly Glu Ala Ala Leu Asn Asp Pro Lys Met Tyr Val Gln Thr 
        35                  40                  45


Val Leu Asp Val His Lys Lys Tyr Asn Ala Leu Val Met Ser Ala Phe 
    50                  55                  60


Asn Asn Asp Ala Gly Phe Val Ala Ala Leu Asp Lys Ala Cys Gly Arg 
65                  70                  75                  80


Phe Ile Asn Asn Asn Ala Val Thr Lys Met Ala Gln Ser Ser Ser Lys 
                85                  90                  95


Ser Pro Glu Leu Leu Ala Arg Tyr Cys Asp Ser Leu Leu Lys Lys Ser 
            100                 105                 110


Ser Lys Asn Pro Glu Glu Ala Glu Leu Glu Asp Thr Leu Asn Gln Val 
        115                 120                 125


Met Val Val Phe Lys Tyr Ile Glu Asp Lys Asp Val Phe Gln Lys Phe 
    130                 135                 140


Tyr Ala Lys Met Leu Ala Lys Arg Leu Val His Gln Asn Ser Ala Ser 
145                 150                 155                 160


Asp Asp Ala Glu Ala Ser Met Ile Ser Lys Leu Lys Gln Ala Cys Gly 
                165                 170                 175


Phe Glu Tyr Thr Ser Lys Leu Gln Arg Met Phe Gln Asp Ile Gly Val 
            180                 185                 190


Ser Lys Asp Leu Asn Glu Gln Phe Lys Lys His Leu Thr Asn Ser Glu 
        195                 200                 205


Pro Leu Asp Leu Asp Phe Ser Ile Gln Val Leu Ser Ser Gly Ser Trp 
    210                 215                 220


Pro Phe Gln Gln Ser Cys Thr Phe Ala Leu Pro Ser Glu Leu Glu Arg 
225                 230                 235                 240


Ser Tyr Gln Arg Phe Thr Ala Phe Tyr Ala Ser Arg His Ser Gly Arg 
                245                 250                 255


Lys Leu Thr Trp Leu Tyr Gln Leu Ser Lys Gly Glu Leu Val Thr Asn 
            260                 265                 270


Cys Phe Lys Asn Arg Tyr Thr Leu Gln Ala Ser Thr Phe Gln Met Ala 
        275                 280                 285


Ile Leu Leu Gln Tyr Asn Thr Glu Asp Ala Tyr Thr Val Gln Gln Leu 
    290                 295                 300


Thr Asp Ser Thr Gln Ile Lys Met Asp Ile Leu Ala Gln Val Leu Gln 
305                 310                 315                 320


Ile Leu Leu Lys Ser Lys Leu Leu Val Leu Glu Asp Glu Asn Ala Asn 
                325                 330                 335


Val Asp Glu Val Glu Leu Lys Pro Asp Thr Leu Ile Lys Leu Tyr Leu 
            340                 345                 350


Gly Tyr Lys Asn Lys Lys Leu Arg Val Asn Ile Asn Val Pro Met Lys 
        355                 360                 365


Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile Glu Glu 
    370                 375                 380


Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met Lys Met 
385                 390                 395                 400


Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu Thr Gln 
                405                 410                 415


Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Lys Cys Ile 
            420                 425                 430


Asp Ile Leu Ile Glu Lys Glu Tyr Leu Glu Arg Val Asp Gly Glu Lys 
        435                 440                 445


Asp Thr Tyr Ser Tyr Leu Ala 
    450                 455


<210>  5450
<211>  2518
<212>  DNA
<213>  Homo sapiens

<400>  5450
gtgcttggct gggggtgacc cggagctccc tcccaccaac cttcccagcc gggctccctc     60

gcagcccgga gccaagcctg tgcctgccac catttcctgg cagtgtgctt agctgtgaca    120

gtttctacgt ctgtagaatg gggatgaaaa cagcacctgc tgcccagtgt gggctttcgc    180

ggtctcatga agggtggtgg cggcgtgcgc tgcatgccta gcagcagcgc tgtttttctc    240

attagcactt agctccgtct cctttgcctt ccattgtcgc cgccttcctt tggccacagg    300

agcctctgcg gccagccttc ccgttgcatt tccatgttgt tccttgttcc ggggaggccc    360

ctttgctgcc ctgcgccgcg ctccgcccct cttcccgtcc tgcgatgagg ccctggcccc    420

cggcatcgcc acgcggatcc gcgcctctgg tttgcagtgg gtgggggccg cagtcagact    480

cccgccctga gccccgcttt ccctcgcgtt gcctgcccag ccgggctgat gaccgacctc    540

ggcggctaaa cgccttctcc agctgaaaca gagtccagag ttccactgtt taacaaggag    600

gaattggcaa agcagaactg tcacttggaa aatgctgttt tcatgatctc tttgagtttt    660

cactgttttt aatgcaagct cggaatcaat atttagtttt gagtgtggag aatagattgt    720

tttttctttt atatatataa acaaaatgtc ctatgtgttt caacgatggt accaaaagta    780

tttcttgctc ttatctctta actttgaaaa ggaccccaaa atgtatgtac agacagtgct    840

tgatgttcat aaaaaataca atgccctggt aatgtctgca ttcaacaatg acgctggctt    900

tgtggctgct cttgataagg cttgtggtcg cttcataaac aacaacgcgg ttaccaagat    960

ggcccaatca tccagtaaat cccctgagtt gctggctcga tactgtgact ccttgttgaa   1020

gaaaagttcc aagaacccag aggaggcaga actagaagac acactcaatc aagtgatggt   1080

tgtcttcaag tacatagaag acaaagacgt atttcagaag ttctatgcga agatgctcgc   1140

caagaggctc gtccaccaga acagtgcaag tgacgatgcc gaagccagca tgatctccaa   1200

gttaaagcaa gcttgcgggt tcgagtacac ctctaaactt cagcgcatgt ttcaagacat   1260

tggcgtgagc aaagatctga acgagcaatt caaaaagcac ttgacaaact cagaacccct   1320

agacttggat ttcagcattc aagtgctgag ctccgggtcc tggcccttcc agcagtcttg   1380

tacatttgcc ttgccgtcag agttggaacg tagttatcag cgattcacag ctttctacgc   1440

cagccgccac agtggccgaa aattgacgtg gttatatcag ttgtctaaag gagaattggt   1500

aactaactgc ttcaaaaaca gatatacttt gcaggcgtcg acattccaga tggctatcct   1560

gcttcagtac aacacggaag atgcctacac tgtgcagcag ctgaccgaca gcactcaaat   1620

taaaatggac attttggcgc aagttttaca gattttatta aagtcgaagc tattggtctt   1680

ggaagatgaa aatgcaaatg ttgatgaggt ggaattgaag ccagatacct taataaaatt   1740

atatcttggt tataaaaata agaaattaag ggttaacatc aatgtgccaa tgaaaaccga   1800

acagaagcag gaacaagaaa ccacacacaa aaacatcgag gaagaccgca aactactgat   1860

tcaggcggcc atcgtgagaa tcatgaagat gaggaaggtt ctgaaacacc agcagttact   1920

tggcgaggtc ctcactcagc tgtcctccag gttcaaacct cgagtccctg tgatcaagaa   1980

atgcattgac attctaattg agaaagaata tttggagcga gtggatggtg aaaaggacac   2040

ctacagttac ttggcttaac ccttctggaa gggtctgact gtgtgacccg cagcaaatag   2100

ttcatgttgg aaagaatgaa aacaactcaa gttcatagca gccagcctgc cgccattgga   2160

cctccctttt aaaaactgag accaagactc ccatcagctg gtctcggatt tacatcggaa   2220

ctgctcagga ttgatacatt tcaagtctgt aaatacggac accaacgcca tttaccctaa   2280

tttaagaaca gcggggactg accctccgtg ccgagggctg catgctaccg cactaagtca   2340

atacatgggc tccccgattc gcagctgtcg tcttggcagc acttgtcacg ttggcagcac   2400

tttgagagca agtctgagtg gacccacatg taacctgcta tgaaaaccat ttgtatagtg   2460

tgtttcattt tttaatgtgt gaaaataaag aaaattaaag gatttctgta caagtcgc     2518


<210>  5451
<211>  437
<212>  PRT
<213>  Homo sapiens

<400>  5451

Met Ser Tyr Val Phe Gln Arg Trp Tyr Gln Lys Tyr Phe Leu Leu Leu 
1               5                   10                  15


Ser Leu Asn Phe Glu Lys Asp Pro Lys Met Tyr Val Gln Thr Val Leu 
            20                  25                  30


Asp Val His Lys Lys Tyr Asn Ala Leu Val Met Ser Ala Phe Asn Asn 
        35                  40                  45


Asp Ala Gly Phe Val Ala Ala Leu Asp Lys Ala Cys Gly Arg Phe Ile 
    50                  55                  60


Asn Asn Asn Ala Val Thr Lys Met Ala Gln Ser Ser Ser Lys Ser Pro 
65                  70                  75                  80


Glu Leu Leu Ala Arg Tyr Cys Asp Ser Leu Leu Lys Lys Ser Ser Lys 
                85                  90                  95


Asn Pro Glu Glu Ala Glu Leu Glu Asp Thr Leu Asn Gln Val Met Val 
            100                 105                 110


Val Phe Lys Tyr Ile Glu Asp Lys Asp Val Phe Gln Lys Phe Tyr Ala 
        115                 120                 125


Lys Met Leu Ala Lys Arg Leu Val His Gln Asn Ser Ala Ser Asp Asp 
    130                 135                 140


Ala Glu Ala Ser Met Ile Ser Lys Leu Lys Gln Ala Cys Gly Phe Glu 
145                 150                 155                 160


Tyr Thr Ser Lys Leu Gln Arg Met Phe Gln Asp Ile Gly Val Ser Lys 
                165                 170                 175


Asp Leu Asn Glu Gln Phe Lys Lys His Leu Thr Asn Ser Glu Pro Leu 
            180                 185                 190


Asp Leu Asp Phe Ser Ile Gln Val Leu Ser Ser Gly Ser Trp Pro Phe 
        195                 200                 205


Gln Gln Ser Cys Thr Phe Ala Leu Pro Ser Glu Leu Glu Arg Ser Tyr 
    210                 215                 220


Gln Arg Phe Thr Ala Phe Tyr Ala Ser Arg His Ser Gly Arg Lys Leu 
225                 230                 235                 240


Thr Trp Leu Tyr Gln Leu Ser Lys Gly Glu Leu Val Thr Asn Cys Phe 
                245                 250                 255


Lys Asn Arg Tyr Thr Leu Gln Ala Ser Thr Phe Gln Met Ala Ile Leu 
            260                 265                 270


Leu Gln Tyr Asn Thr Glu Asp Ala Tyr Thr Val Gln Gln Leu Thr Asp 
        275                 280                 285


Ser Thr Gln Ile Lys Met Asp Ile Leu Ala Gln Val Leu Gln Ile Leu 
    290                 295                 300


Leu Lys Ser Lys Leu Leu Val Leu Glu Asp Glu Asn Ala Asn Val Asp 
305                 310                 315                 320


Glu Val Glu Leu Lys Pro Asp Thr Leu Ile Lys Leu Tyr Leu Gly Tyr 
                325                 330                 335


Lys Asn Lys Lys Leu Arg Val Asn Ile Asn Val Pro Met Lys Thr Glu 
            340                 345                 350


Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile Glu Glu Asp Arg 
        355                 360                 365


Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met Lys Met Arg Lys 
    370                 375                 380


Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu Thr Gln Leu Ser 
385                 390                 395                 400


Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Lys Cys Ile Asp Ile 
                405                 410                 415


Leu Ile Glu Lys Glu Tyr Leu Glu Arg Val Asp Gly Glu Lys Asp Thr 
            420                 425                 430


Tyr Ser Tyr Leu Ala 
        435


<210>  5452
<211>  945
<212>  DNA
<213>  Homo sapiens

<400>  5452
gattgatgct taacatgtcc atatatacca ggtgtgtgta tatgtgattg tctctataaa     60

tgcgtgggga cgtatctata gtatgtatcc acatagacaa tacgtttttt aaaaaaaacc    120

ctcaaattat tttaatgttt gtaaacatgg aaaatgaatg actttgggaa aatgttgcat    180

tgtagtggca ttgccacgtt ttatattccc ttttaaatag atctgtgctt tttttgtact    240

tgtttaaaga atttgtttca taaataagtt cttcaaactt gggctgtata ttttgggagg    300

tgtttccatg catgtaaatt ttccttcttt ttcttttata tggggggccg caaaggcgtc    360

gacattccag atggctatcc tgcttcagta caacacggaa gatgcctaca ctgtgcagca    420

gctgaccgac agcactcaaa ttaaaatgga cattttggcg caagttttac agattttatt    480

aaagtcgaag ctattggtct tggaagatga aaatgcaaat gttgatgagg tggaattgaa    540

gccagatacc ttaataaaat tatatcttgg ttataaaaat aagaaattaa gggttaacat    600

caatgtgcca atgaaaaccg aacagaagca ggaacaagaa accacacaca aaaacatcga    660

ggaagaccgc aaactactga ttcaggtgac ttatctgtat gcctgtgcca ggtgtgctgt    720

ccctcacgca gggatggctc gcaaggacgg gccgtggggg gtaggcgggg gtgacaaagg    780

agtgattgcc agatgaatgg gtctgtgatg gcagaaggtg gcaaggccga gagccagggc    840

cttgttatct gaattagtcc tttatgtcac caggcaaaac agggcagtcc tcttgctcta    900

aatgttggaa agcaaacatt gtggcaggtt tggctgaaat gaggg                    945


<210>  5453
<211>  162
<212>  PRT
<213>  Homo sapiens

<400>  5453

Met His Val Asn Phe Pro Ser Phe Ser Phe Ile Trp Gly Ala Ala Lys 
1               5                   10                  15


Ala Ser Thr Phe Gln Met Ala Ile Leu Leu Gln Tyr Asn Thr Glu Asp 
            20                  25                  30


Ala Tyr Thr Val Gln Gln Leu Thr Asp Ser Thr Gln Ile Lys Met Asp 
        35                  40                  45


Ile Leu Ala Gln Val Leu Gln Ile Leu Leu Lys Ser Lys Leu Leu Val 
    50                  55                  60


Leu Glu Asp Glu Asn Ala Asn Val Asp Glu Val Glu Leu Lys Pro Asp 
65                  70                  75                  80


Thr Leu Ile Lys Leu Tyr Leu Gly Tyr Lys Asn Lys Lys Leu Arg Val 
                85                  90                  95


Asn Ile Asn Val Pro Met Lys Thr Glu Gln Lys Gln Glu Gln Glu Thr 
            100                 105                 110


Thr His Lys Asn Ile Glu Glu Asp Arg Lys Leu Leu Ile Gln Val Thr 
        115                 120                 125


Tyr Leu Tyr Ala Cys Ala Arg Cys Ala Val Pro His Ala Gly Met Ala 
    130                 135                 140


Arg Lys Asp Gly Pro Trp Gly Val Gly Gly Gly Asp Lys Gly Val Ile 
145                 150                 155                 160


Ala Arg 



<210>  5454
<211>  2625
<212>  DNA
<213>  Homo sapiens

<400>  5454
ggcgcaagtt ttacagattt tattaaagtc gaagctattg gtaggtttgc gcccttttat     60

cttacactag aagaagcctt ttcctgagat tgtagagtaa caattgtttt cttacaggtc    120

ttggaagatg aaaatgcaaa tgttgatgag gtggaattga agccagatac cttaataaaa    180

ttatatcttg gttataaaaa gtaagaaaaa tctaataagt agatggccct tgaccataga    240

cacgtccccc gggagcccta gcacggatct cagtattgtt acaaaccaag ggagaccggg    300

gactcagtgt gaagcgacag gcactaggct gggagtgtga ggtaggcctt tgattccatt    360

cagcgagcct gatgtttctc caattctgag cttctgggat ttttattatt ttggcaaata    420

agtctcctta aatggctcac caagaaagtt tggacctttg tgtccaagtg gcttgatttt    480

atctcacttg acaaaatttg ggagagcaga ttagggacct ggattttctg taatgtggat    540

gtccctgtta atggccgagt aggaaactag gccatgatcg gactctaccc agtgctgggt    600

agaggacatt ttcacggaga gctcacagaa atcaacattc tcccctctgt ctagggaagc    660

agggcacttc ttaaaggttg aaaaatagaa agcagccttc actgcctacc ttttaatata    720

atagtgatcg gtttcctcat ttttcttgat agtaagaaat taagggttaa catcaatgtg    780

ccaatgaaaa ccgaacagaa gcaggaacaa gaaaccacac acaaaaacat cgaggaagac    840

cgcaaactac tgattcaggc ggccatcgtg agaatcatga agatgaggaa ggttctgaaa    900

caccagcagt tacttggcga ggtcctcact cagctgtcct ccaggttcaa acctcgagtc    960

cctgtgatca aggtacagga ctttacatag cagtcacatt cctttcttaa tttagaagat   1020

aaaagatgta gcaaaaagtg gattgattgc tgtagcatga aggaggaggg agctggcttc   1080

tttgtatgta gatttctata aaagaaagtc ggcttcagtt taactgttga aacacacata   1140

caaagtgcac agatgatgaa gtgccagctt gatgactttc acagtcaata cactgtgtga   1200

tcagcaccca ggtaagaatt gaaacatgcc cggcatcccg gaagcccacc caccccagcc   1260

agcacctgtg tcccatagaa aatcactgtc gtgtcttctg acaccataaa acagttttgc   1320

ctgcttttgc gtgatacata aacagattct agagcacaca ctcccgtgcc tggtaagaat   1380

ttcctcagca gtatcttcgg gaggttcgtc gcattgcggt atcgagaagc actgggtcgt   1440

ttttgttgct tttatgggtg ttgtgttatg ggaacacacc ttcctttatg tagcctactg   1500

ataattgaca ttttgcttat ttctgattgg gtttgtttaa aatggtaact aagcaggact   1560

ttccttttcc taaaccactt gggtaagtca cagccagtgg agagactcag gggtggcatt   1620

gacaggtgac ttccccaaca ggcaggaggc ccagtgtccc tcctgggtta catttggcac   1680

aggtgccagt tcgttcatgg ctgttcaggg agttccccac agtcccctgt tccctgttca   1740

tggcctcttc ttgtgagact gagtcctgcc gcagaggcag gcagattttg gtggtagaaa   1800

gggagactgg cccacggggc tcccgaagca cctgactcca gttcctaggg cgggtgcagg   1860

agggactcgg agtcaccctc agcaagtgtc agggagctcc gtgcatgaag gcttagctgc   1920

caggaagtaa aactctatgc taacagatct ggggcgggga cactgctccc cactgagctc   1980

cgaatcaggg gagatttgtg gtgggggcag cctctctctg ttctgatgat aatttgtgtt   2040

tttcttctct ttcactacct cttccttttt aaaaataaca cccagaaatg cattgacatt   2100

ctaattgaga aagaatattt ggagcgagtg gatggtgaaa aggacaccta cagttacttg   2160

gcttaaccct tctggaaggg tctgactgtg tgacccgcag caaatagttc atgttggaaa   2220

gaatgaaaac aactcaagtt catagcagcc agcctgccgc cattggacct cccttttaaa   2280

aactgagacc aagactccca tcagctggtc tcggatttac atcggaactg ctcaggattg   2340

atacatttca agtctgtaaa tacggacacc aacgccattt accctaattt aagaacagcg   2400

gggactgacc ctccgtgccg agggctgcat gctaccgcac taagtcaata catgggctcc   2460

ccgattcgca gctgtcgtct tggcagcact tgtcacgttg gcagcacttt gagagcaagt   2520

ctgagtggac ccacatgtaa cctgctatga aaaccatttg tatagtgtgt ttcatttttt   2580

aatgtgtgaa aataaagaaa attaaaggat ttctgtacaa gtcgc                   2625


<210>  5455
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  5455

Met Lys Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile 
1               5                   10                  15


Glu Glu Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met 
            20                  25                  30


Lys Met Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu 
        35                  40                  45


Thr Gln Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Val 
    50                  55                  60


Gln Asp Phe Thr 
65


<210>  5456
<211>  2696
<212>  DNA
<213>  Homo sapiens

<400>  5456
ggcgcaagtt ttacagattt tattaaagtc gaagctattg gtaggtttgc gcccttttat     60

cttacactag aagaagcctt ttcctgagat tgtagagtaa caattgtttt cttacaggtc    120

ttggaagatg aaaatgcaaa tgttgatgag gtggaattga agccagatac cttaataaaa    180

ttatatcttg gttataaaaa gtaagaaaaa tctaataagt agatggccct tgaccataga    240

cacgtccccc gggagcccta gcacggatct cagtattgtt acaaaccaag ggagaccggg    300

gactcagtgt gaagcgacag gcactaggct gggagtgtga ggtaggcctt tgattccatt    360

cagcgagcct gatgtttctc caattctgag cttctgggat ttttattatt ttggcaaata    420

agtctcctta aatggctcac caagaaagtt tggacctttg tgtccaagtg gcttgatttt    480

atctcacttg acaaaatttg ggagagcaga ttagggacct ggattttctg taatgtggat    540

gtccctgtta atggccgagt aggaaactag gccatgatcg gactctaccc agtgctgggt    600

agaggacatt ttcacggaga gctcacagaa atcaacattc tcccctctgt ctagggaagc    660

agggcacttc ttaaaggttg aaaaatagaa agcagccttc actgcctacc ttttaatata    720

atagtgatcg gtttcctcat ttttcttgat agtaagaaat taagggttaa catcaatgtg    780

ccaatgaaaa ccgaacagaa gcaggaacaa gaaaccacac acaaaaacat cgaggaagac    840

cgcaaactac tgattcaggc ggccatcgtg agaatcatga agatgaggaa ggttctgaaa    900

caccagcagt tacttggcga ggtcctcact cagctgtcct ccaggttcaa acctcgagtc    960

cctgtgatca aggtacagga ctttacatag cagtcacatt cctttcttaa tttagaagat   1020

aaaagatgta gcaaaaagtg gattgattgc tgtagcatga aggaggaggg agctggcttc   1080

tttgtatgta gatttctata aaagaaagtc ggcttcagtt taactgttga aacacacata   1140

caaagtgcac agatgatgaa gtgccagctt gatgactttc acagtcaata cactgtgtga   1200

tcagcaccca ggtaagaatt gaaacatgcc cggcatcccg gaagcccacc caccccagcc   1260

agcacctgtg tcccatagaa aatcactgtc gtgtcttctg acaccataaa acagttttgc   1320

ctgcttttgc gtgatacata aacagattct agagcacaca ctcccgtgcc tggtaagaat   1380

ttcctcagca gtatcttcgg gaggttcgtc gcattgcggt atcgagaagc actgggtcgt   1440

ttttgttgct tttatgggtg ttgtgttatg ggaacacacc ttcctttatg tagcctactg   1500

ataattgaca ttttgcttat ttctgattgg gtttgtttaa aatggtaact aagcaggact   1560

ttccttttcc taaaccactt gggtaagtca cagccagtgg agagactcag gggtggcatt   1620

gacaggtgac ttccccaaca ggcaggaggc ccagtgtccc tcctgggtta catttggcac   1680

aggtgccagt tcgttcatgg ctgttcaggg agttccccac agtcccctgt tccctgttca   1740

tggcctcttc ttgtgagact gagtcctgcc gcagaggcag gcagattttg gtggtagaaa   1800

gggagactgg cccacggggc tcccgaagca cctgactcca gttcctaggg cgggtgcagg   1860

agggactcgg agtcaccctc agcaagtgtc agggagctcc gtgcatgaag gcttagctgc   1920

caggaagtaa aactctatgc taacagatct ggggcgggga cactgctccc cactgagctc   1980

cgaatcaggg gagatttgtg gtgggggcag cctctctctg ttctgatgat aatttgtgtt   2040

tttcttctct ttcactacct cttccttttt aaaaataaca cccagaaatg cattgacatt   2100

ctaattgaga aagaatattt ggagcgagtg gatggtgaaa aggacaccta cagttacttg   2160

gcttaaccct tctggaaggg tctgactgtg tgacccgcag caaatagttc atgttggaaa   2220

gaatgaaaac aactcaagtt catagcagcc agcctgccgc cattggacct cccttttaaa   2280

aactgagacc aagactccca tcagctggtc tcggatttac atcggaactg ctcaggattg   2340

atacatttca agtctgtaaa tacggacacc aacgccattt accctaattt aagaacagcg   2400

gggactgacc ctccgtgccg agggctgcat gctaccgcac taagtcaata catgggctcc   2460

ccgattcgca gctgtcgtct tggcagcact tgtcacgttg gcagcacttt gagagcaagt   2520

ctgagtggac ccacatgtaa cctgctatga aaaccatttg tatagtgtgt ttcatttttt   2580

aatgtgtgaa aataaagaaa attaaaggat ttctgtacaa gtcgcattgg gttttgtttt   2640

aagttttact aatttctata tgtaaataaa agatataatg attgtgcaaa tttata       2696


<210>  5457
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  5457

Met Lys Thr Glu Gln Lys Gln Glu Gln Glu Thr Thr His Lys Asn Ile 
1               5                   10                  15


Glu Glu Asp Arg Lys Leu Leu Ile Gln Ala Ala Ile Val Arg Ile Met 
            20                  25                  30


Lys Met Arg Lys Val Leu Lys His Gln Gln Leu Leu Gly Glu Val Leu 
        35                  40                  45


Thr Gln Leu Ser Ser Arg Phe Lys Pro Arg Val Pro Val Ile Lys Val 
    50                  55                  60


Gln Asp Phe Thr 
65


<210>  5458
<211>  1149
<212>  DNA
<213>  Homo sapiens

<400>  5458
acatacaaag tgcacagatg atgaagtgcc agcttgatga ctttcacagt caatacactg     60

tgtgatcagc acccaggtaa gaattgaaac atgcccggca tcccggaagc ccacccaccc    120

cagccagcac ctgtgtccca tagaaaatca ctgtcgtgtc ttctgacacc ataaaacagt    180

tttgcctgct tttgcgtgat acataaacag attctagagc acacactccc gtgcctggta    240

agaatttcct cagcagtatc ttcgggaggt tcgtcgcatt gcggtatcga gaagcactgg    300

gtcgtttttg ttgcttttat gggtgttgtg ttatgggaac acaccttcct ttatgtagcc    360

tactgataat tgacattttg cttatttctg attgggtttg tttaaaatgg taactaagca    420

ggactttcct tttcctaaac cacttgggta agtcacagcc agtggagaga ctcaggggtg    480

gcattgacag gtgacttccc caacaggcag gaggcccagt gtccctcctg ggttacattt    540

ggcacaggtg ccagttcgtt catggctgtt cagggagttc cccacagtcc cctgttccct    600

gttcatggcc tcttcttgtg agactgagtc ctgccgcaga ggcaggcaga ttttggtggt    660

agaaagggag actggcccac ggggctcccg aagcacctga ctccagttcc tagggcgggt    720

gcaggaggga ctcggagtca ccctcagcaa gtgtcaggga gctccgtgca tgaaggctta    780

gctgccagga agtaaaactc tatgctaaca gatctggggc ggggacactg ctccccactg    840

agctccgaat caggggagat ttgtggtggg ggcagcctct ctctgttctg atgataattt    900

gtgtttttct tctctttcac tacctcttcc tttttaaaaa taacacccag aaatgcattg    960

acattctaat tgagaaagaa tatttggagc gagtggatgg tgaaaaggac acctacagtt   1020

acttggctta acccttctgg aagggtctga ctgtgtgacc cgcagcaaat agttcatgtt   1080

ggaaagaatg aaaacatttg tatagtgtgt ttcatttttt aatgtgtgaa aataaagaaa   1140

attaaagga                                                           1149


<210>  5459
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  5459

Met Ile Ile Cys Val Phe Leu Leu Phe His Tyr Leu Phe Leu Phe Lys 
1               5                   10                  15


Asn Asn Thr Gln Lys Cys Ile Asp Ile Leu Ile Glu Lys Glu Tyr Leu 
            20                  25                  30


Glu Arg Val Asp Gly Glu Lys Asp Thr Tyr Ser Tyr Leu Ala 
        35                  40                  45


<210>  5460
<211>  3021
<212>  DNA
<213>  Homo sapiens

<400>  5460
acctatcctc cccgcctccc gtccgcggcg ggctccgggc ccccgcgatg tctcccggtc     60

cccgcgtgcc tgcacaccgc cttcctgaga ggcgccgtgt gttcagcgaa agaacaaaga    120

gacggcggcg gcgcttccac acggccagtg gcgtccctta cagcgaaccc cgccgccgcc    180

cgcgcgcgca cgcgctgcca gtgcccgccc gcccacgagc cctgagcgca ctctgcgtgg    240

ggctggctcg gcgcctccga gcccggcggg ccctgtgatt ggacgggcgc ccgcctcgcg    300

tcccgccaat cggggcggcg cttgattggg ctgggggggc caaataaaag cgatggcgat    360

tgggctgccg cgtttggcgc tcggtccggt cgcgtccgac acccggtggg actcagaagg    420

cagtggagcc ccggcggcgg cggcggcggc gcgcgggggc gacgcgcggg aacaacgcga    480

gtcggcgcgc gggacgaaga ataatcatgg gccagactgg gaagaaatct gagaagggac    540

cagtttgttg gcggaagcgt gtaaaatcag agtacatgcg actgagacag ctcaagaggt    600

tcagacgagc tgatgaagta aagagtatgt ttagttccaa tcgtcagaaa attttggaaa    660

gaacggaaat cttaaaccaa gaatggaaac agcgaaggat acagcctgtg cacatcctga    720

cttctgtgag ctcattgcgc gggactaggg agtgttcggt gaccagtgac ttggattttc    780

caacacaagt catcccatta aagactctga atgcagttgc ttcagtaccc ataatgtatt    840

cttggtctcc cctacagcag aattttatgg tggaagatga aactgtttta cataacattc    900

cttatatggg agatgaagtt ttagatcagg atggtacttt cattgaagaa ctaataaaaa    960

attatgatgg gaaagtacac ggggatagag aatgtgggtt tataaatgat gaaatttttg   1020

tggagttggt gaatgccctt ggtcaatata atgatgatga cgatgatgat gatggagacg   1080

atcctgaaga aagagaagaa aagcagaaag atctggagga tcaccgagat gataaagaaa   1140

gccgcccacc tcggaaattt ccttctgata aaatttttga agccatttcc tcaatgtttc   1200

cagataaggg cacagcagaa gaactaaagg aaaaatataa agaactcacc gaacagcagc   1260

tcccaggcgc acttcctcct gaatgtaccc ccaacataga tggaccaaat gctaaatctg   1320

ttcagagaga gcaaagctta cactcctttc atacgctttt ctgtaggcga tgttttaaat   1380

atgactgctt cctacatcct tttcatgcaa cacccaacac ttataagcgg aagaacacag   1440

aaacagctct agacaacaaa ccttgtggac cacagtgtta ccagcatttg gagggagcaa   1500

aggagtttgc tgctgctctc accgctgagc ggataaagac cccaccaaaa cgtccaggag   1560

gccgcagaag aggacggctt cccaataaca gtagcaggcc cagcaccccc accattaatg   1620

tgctggaatc aaaggataca gacagtgata gggaagcagg gactgaaacg gggggagaga   1680

acaatgataa agaagaagaa gagaagaaag atgaaacttc gagctcctct gaagcaaatt   1740

ctcggtgtca aacaccaata aagatgaagc caaatattga acctcctgag aatgtggagt   1800

ggagtggtgc tgaagcctca atgtttagag tcctcattgg cacttactat gacaatttct   1860

gtgccattgc taggttaatt gggaccaaaa catgtagaca ggtgtatgag tttagagtca   1920

aagaatctag catcatagct ccagctcccg ctgaggatgt ggatactcct ccaaggaaaa   1980

agaagaggaa acaccggttg tgggctgcac actgcagaaa gatacagctg aaaaaggacg   2040

gctcctctaa ccatgtttac aactatcaac cctgtgatca tccacggcag ccttgtgaca   2100

gttcgtgccc ttgtgtgata gcacaaaatt tttgtgaaaa gttttgtcaa tgtagttcag   2160

agtgtcaaaa ccgctttccg ggatgccgct gcaaagcaca gtgcaacacc aagcagtgcc   2220

cgtgctacct ggctgtccga gagtgtgacc ctgacctctg tcttacttgt ggagccgctg   2280

accattggga cagtaaaaat gtgtcctgca agaactgcag tattcagcgg ggctccaaaa   2340

agcatctatt gctggcacca tctgacgtgg caggctgggg gatttttatc aaagatcctg   2400

tgcagaaaaa tgaattcatc tcagaatact gtggagagat tatttctcaa gatgaagctg   2460

acagaagagg gaaagtgtat gataaataca tgtgcagctt tctgttcaac ttgaacaatg   2520

attttgtggt ggatgcaacc cgcaagggta acaaaattcg ttttgcaaat cattcggtaa   2580

atccaaactg ctatgcaaaa gttatgatgg ttaacggtga tcacaggata ggtatttttg   2640

ccaagagagc catccagact ggcgaagagc tgttttttga ttacagatac agccaggctg   2700

atgccctgaa gtatgtcggc atcgaaagag aaatggaaat cccttgacat ctgctacctc   2760

ctcccccctc ctctgaaaca gctgccttag cttcaggaac ctcgagtact gtgggcaatt   2820

tagaaaaaga acatgcagtt tgaaattctg aatttgcaaa gtactgtaag aataatttat   2880

agtaatgagt ttaaaaatca actttttatt gccttctcac cagctgcaaa gtgttttgta   2940

ccagtgaatt tttgcaataa tgcagtatgg tacatttttc aactttgaat aaagaatact   3000

tgaacttgtc cttgttgaat c                                             3021


<210>  5461
<211>  746
<212>  PRT
<213>  Homo sapiens

<400>  5461

Met Gly Gln Thr Gly Lys Lys Ser Glu Lys Gly Pro Val Cys Trp Arg 
1               5                   10                  15


Lys Arg Val Lys Ser Glu Tyr Met Arg Leu Arg Gln Leu Lys Arg Phe 
            20                  25                  30


Arg Arg Ala Asp Glu Val Lys Ser Met Phe Ser Ser Asn Arg Gln Lys 
        35                  40                  45


Ile Leu Glu Arg Thr Glu Ile Leu Asn Gln Glu Trp Lys Gln Arg Arg 
    50                  55                  60


Ile Gln Pro Val His Ile Leu Thr Ser Val Ser Ser Leu Arg Gly Thr 
65                  70                  75                  80


Arg Glu Cys Ser Val Thr Ser Asp Leu Asp Phe Pro Thr Gln Val Ile 
                85                  90                  95


Pro Leu Lys Thr Leu Asn Ala Val Ala Ser Val Pro Ile Met Tyr Ser 
            100                 105                 110


Trp Ser Pro Leu Gln Gln Asn Phe Met Val Glu Asp Glu Thr Val Leu 
        115                 120                 125


His Asn Ile Pro Tyr Met Gly Asp Glu Val Leu Asp Gln Asp Gly Thr 
    130                 135                 140


Phe Ile Glu Glu Leu Ile Lys Asn Tyr Asp Gly Lys Val His Gly Asp 
145                 150                 155                 160


Arg Glu Cys Gly Phe Ile Asn Asp Glu Ile Phe Val Glu Leu Val Asn 
                165                 170                 175


Ala Leu Gly Gln Tyr Asn Asp Asp Asp Asp Asp Asp Asp Gly Asp Asp 
            180                 185                 190


Pro Glu Glu Arg Glu Glu Lys Gln Lys Asp Leu Glu Asp His Arg Asp 
        195                 200                 205


Asp Lys Glu Ser Arg Pro Pro Arg Lys Phe Pro Ser Asp Lys Ile Phe 
    210                 215                 220


Glu Ala Ile Ser Ser Met Phe Pro Asp Lys Gly Thr Ala Glu Glu Leu 
225                 230                 235                 240


Lys Glu Lys Tyr Lys Glu Leu Thr Glu Gln Gln Leu Pro Gly Ala Leu 
                245                 250                 255


Pro Pro Glu Cys Thr Pro Asn Ile Asp Gly Pro Asn Ala Lys Ser Val 
            260                 265                 270


Gln Arg Glu Gln Ser Leu His Ser Phe His Thr Leu Phe Cys Arg Arg 
        275                 280                 285


Cys Phe Lys Tyr Asp Cys Phe Leu His Pro Phe His Ala Thr Pro Asn 
    290                 295                 300


Thr Tyr Lys Arg Lys Asn Thr Glu Thr Ala Leu Asp Asn Lys Pro Cys 
305                 310                 315                 320


Gly Pro Gln Cys Tyr Gln His Leu Glu Gly Ala Lys Glu Phe Ala Ala 
                325                 330                 335


Ala Leu Thr Ala Glu Arg Ile Lys Thr Pro Pro Lys Arg Pro Gly Gly 
            340                 345                 350


Arg Arg Arg Gly Arg Leu Pro Asn Asn Ser Ser Arg Pro Ser Thr Pro 
        355                 360                 365


Thr Ile Asn Val Leu Glu Ser Lys Asp Thr Asp Ser Asp Arg Glu Ala 
    370                 375                 380


Gly Thr Glu Thr Gly Gly Glu Asn Asn Asp Lys Glu Glu Glu Glu Lys 
385                 390                 395                 400


Lys Asp Glu Thr Ser Ser Ser Ser Glu Ala Asn Ser Arg Cys Gln Thr 
                405                 410                 415


Pro Ile Lys Met Lys Pro Asn Ile Glu Pro Pro Glu Asn Val Glu Trp 
            420                 425                 430


Ser Gly Ala Glu Ala Ser Met Phe Arg Val Leu Ile Gly Thr Tyr Tyr 
        435                 440                 445


Asp Asn Phe Cys Ala Ile Ala Arg Leu Ile Gly Thr Lys Thr Cys Arg 
    450                 455                 460


Gln Val Tyr Glu Phe Arg Val Lys Glu Ser Ser Ile Ile Ala Pro Ala 
465                 470                 475                 480


Pro Ala Glu Asp Val Asp Thr Pro Pro Arg Lys Lys Lys Arg Lys His 
                485                 490                 495


Arg Leu Trp Ala Ala His Cys Arg Lys Ile Gln Leu Lys Lys Asp Gly 
            500                 505                 510


Ser Ser Asn His Val Tyr Asn Tyr Gln Pro Cys Asp His Pro Arg Gln 
        515                 520                 525


Pro Cys Asp Ser Ser Cys Pro Cys Val Ile Ala Gln Asn Phe Cys Glu 
    530                 535                 540


Lys Phe Cys Gln Cys Ser Ser Glu Cys Gln Asn Arg Phe Pro Gly Cys 
545                 550                 555                 560


Arg Cys Lys Ala Gln Cys Asn Thr Lys Gln Cys Pro Cys Tyr Leu Ala 
                565                 570                 575


Val Arg Glu Cys Asp Pro Asp Leu Cys Leu Thr Cys Gly Ala Ala Asp 
            580                 585                 590


His Trp Asp Ser Lys Asn Val Ser Cys Lys Asn Cys Ser Ile Gln Arg 
        595                 600                 605


Gly Ser Lys Lys His Leu Leu Leu Ala Pro Ser Asp Val Ala Gly Trp 
    610                 615                 620


Gly Ile Phe Ile Lys Asp Pro Val Gln Lys Asn Glu Phe Ile Ser Glu 
625                 630                 635                 640


Tyr Cys Gly Glu Ile Ile Ser Gln Asp Glu Ala Asp Arg Arg Gly Lys 
                645                 650                 655


Val Tyr Asp Lys Tyr Met Cys Ser Phe Leu Phe Asn Leu Asn Asn Asp 
            660                 665                 670


Phe Val Val Asp Ala Thr Arg Lys Gly Asn Lys Ile Arg Phe Ala Asn 
        675                 680                 685


His Ser Val Asn Pro Asn Cys Tyr Ala Lys Val Met Met Val Asn Gly 
    690                 695                 700


Asp His Arg Ile Gly Ile Phe Ala Lys Arg Ala Ile Gln Thr Gly Glu 
705                 710                 715                 720


Glu Leu Phe Phe Asp Tyr Arg Tyr Ser Gln Ala Asp Ala Leu Lys Tyr 
                725                 730                 735


Val Gly Ile Glu Arg Glu Met Glu Ile Pro 
            740                 745


<210>  5462
<211>  4031
<212>  DNA
<213>  Homo sapiens

<400>  5462
acctatcctc cccgcctccc gtccgcggcg ggctccgggc ccccgcgatg tctcccggtc     60

cccgcgtgcc tgcacaccgc cttcctgaga ggcgccgtgt gttcagcgaa agaacaaaga    120

gacggcggcg gcgcttccac acggccagtg gcgtccctta cagcgaaccc cgccgccgcc    180

cgcgcgcgca cgcgctgcca gtgcccgccc gcccacgagc cctgagcgca ctctgcgtgg    240

ggctggctcg gcgcctccga gcccggcggg ccctgtgatt ggacgggcgc ccgcctcgcg    300

tcccgccaat cggggcggcg cttgattggg ctgggggggc caaataaaag cgatggcgat    360

tgggctgccg cgtttggcgc tcggtccggt cgcgtccgac acccggtggg actcagaagg    420

cagtggagcc ccggcggcgg cggcggcggc gcgcgggggc gacgcgcggg aacaacgcga    480

gtcggcgcgc gggacgaaga ataatcatgg gccagactgg gaagaaatct gagaagggac    540

cagtttgttg gcggaagcgt gtaaaatcag agtacatgcg actgagacag ctcaagaggt    600

tcagacgagc tgatgaagta aagagtatgt ttagttccaa tcgtcagaaa attttggaaa    660

gaacggaaat cttaaaccaa gaatggaaac agcgaaggat acagcctgtg cacatcctga    720

cttctgtgag ctcattgcgc gggactaggg agtgttcggt gaccagtgac ttggattttc    780

caacacaagt catcccatta aagactctga atgcagttgc ttcagtaccc ataatgtatt    840

cttggtctcc cctacagcag aattttatgg tggaagatga aactgtttta cataacattc    900

cttatatggg agatgaagtt ttagatcagg atggtacttt cattgaagaa ctaataaaaa    960

attatgatgg gaaagtacac ggggatagag aatgtgggtt tataaatgat gaaatttttg   1020

tggagttggt gaatgccctt ggtcaatata atgatgatga cgatgatgat gatggagacg   1080

atcctgaaga aagagaagaa aagcagaaag atctggagga tcaccgagat gataaagaaa   1140

gccgcccacc tcggaaattt ccttctgata aaatttttga agccatttcc tcaatgtttc   1200

cagataaggg cacagcagaa gaactaaagg aaaaatataa agaactcacc gaacagcagc   1260

tcccaggcgc acttcctcct gaatgtaccc ccaacataga tggaccaaat gctaaatctg   1320

ttcagagaga gcaaagctta cactcctttc atacgctttt ctgtaggcga tgttttaaat   1380

atgactgctt cctacatcct tttcatgcaa cacccaacac ttataagcgg aagaacacag   1440

aaacagctct agacaacaaa ccttgtggac cacagtgtta ccagcatttg ccactcctac   1500

ctaggaacta aatgggtata tattgcctgt tggattttgg acagaagatt cattgaatgg   1560

cacctgcaga aggagggagc aaaggagttt gctgctgctc tcaccgctga gcggataaag   1620

accccaccaa aacgtccagg aggccgcaga agaggacggc ttcccaataa cagtagcagg   1680

cccagcaccc ccaccattaa tgtgctggaa tcaaaggata cagacagtga tagggaagca   1740

gggactgaaa cggggggaga gaacaatgat aaagaagaag aagagaagaa agatgaaact   1800

tcgagctcct ctggtaagac acgtctaata actgggtttt actgttctgt gaaagttcgt   1860

gttgtgagga ttaaggatgt ataatgcatt gaataatttt cttagttggt tagtttcagt   1920

ataaagacca gagttatctc aagaatgtgt agctgtgttg tttctgtttc ctgcctgcac   1980

ccgtacccta gcttgtggtg tttgccctgc ttggttgttt gaaagctgat gatgcacttt   2040

attctcattc tttgtgccat tttctttttt cgatctttct caggtaggga ataatgaaat   2100

ttggatcatt tggtttaata ttcttgacgt tctgtgagta gttttgttgg aaaatgtgaa   2160

ctacgatggg ttagtgtttt gccgattgga tttgagttgt cctcatcttt tcgctttttt   2220

cttaagcaca ccctgaattg tacttcttaa tattatttcc aatcatttct tgaccagtgc   2280

ttacatttgg ttttgtagaa gcaaattctc ggtgtcaaac accaataaag atgaagccaa   2340

atattgaacc tcctgagaat gtggagtgga gtggtgctga agcctcaatg tttagagtcc   2400

tcattggcac ttactatgac aatttctgtg ccattgctag gttaattggg accaaaacat   2460

gtagacaggt aagatatccg ataaaaatgt tgttaaaaga gcttcaaaca tagagataaa   2520

actgtactcg ttgtccaaac aaagaaaatt cttggttatt actaagctcc tattcatctc   2580

ctaaaaataa tttttttttc ttcccaagag ggaattgaat gaaaattatt ctccaggtat   2640

gttacagaat ttccccaatg tagactttta aggttagata gcagtagctt ttaaaagcta   2700

gtaagaattg aaatttagca tcacagttct tgaccagaat ataattacag ctacccctaa   2760

tgtgagggta gggacagcga tgtgtgttat atccccagca tctagcagtg tcacagaaga   2820

gacaaagaca tttttctggt atgcatgagt ataagaatgg tttgcctaaa taagactgtc   2880

ctcatggctc tgtgactgtg cctcttgtca ggtgtatgag tttagagtca aagaatctag   2940

catcatagct ccagctcccg ctgaggatgt ggatactcct ccaaggaaaa agaagaggaa   3000

acaccggttg tgggctgcac actgcagaaa gatacagctg aaaaaggacg gctcctctaa   3060

ccatgtttac aactatcaac cctgtgatca tccacggcag ccttgtgaca gttcgtgccc   3120

ttgtgtgata gcacaaaatt tttgtgaaaa gttttgtcaa tgtagttcag agtgtcaaaa   3180

ccgctttccg ggatgccgct gcaaagcaca gtgcaacacc aagcagtgcc cgtgctacct   3240

ggctgtccga gagtgtgacc ctgacctctg tcttacttgt ggagccgctg accattggga   3300

cagtaaaaat gtgtcctgca agaactgcag tattcagcgg ggctccaaaa agcatctatt   3360

gctggcacca tctgacgtgg caggctgggg gatttttatc aaagatcctg tgcagaaaaa   3420

tgaattcatc tcagaatact gtggagagat tatttctcaa gatgaagctg acagaagagg   3480

gaaagtgtat gataaataca tgtgcagctt tctgttcaac ttgaacaatg attttgtggt   3540

ggatgcaacc cgcaagggta acaaaattcg ttttgcaaat cattcggtaa atccaaactg   3600

ctatgcaaaa gttatgatgg ttaacggtga tcacaggata ggtatttttg ccaagagagc   3660

catccagact ggcgaagagc tgttttttga ttacagatac agccaggctg atgccctgaa   3720

gtatgtcggc atcgaaagag aaatggaaat cccttgacat ctgctacctc ctcccccctc   3780

ctctgaaaca gctgccttag cttcaggaac ctcgagtact gtgggcaatt tagaaaaaga   3840

acatgcagtt tgaaattctg aatttgcaaa gtactgtaag aataatttat agtaatgagt   3900

ttaaaaatca actttttatt gccttctcac cagctgcaaa gtgttttgta ccagtgaatt   3960

tttgcaataa tgcagtatgg tacatttttc aactttgaat aaagaatact tgaacttgtc   4020

cttgttgaat c                                                        4031


<210>  5463
<211>  334
<212>  PRT
<213>  Homo sapiens

<400>  5463

Met Gly Gln Thr Gly Lys Lys Ser Glu Lys Gly Pro Val Cys Trp Arg 
1               5                   10                  15


Lys Arg Val Lys Ser Glu Tyr Met Arg Leu Arg Gln Leu Lys Arg Phe 
            20                  25                  30


Arg Arg Ala Asp Glu Val Lys Ser Met Phe Ser Ser Asn Arg Gln Lys 
        35                  40                  45


Ile Leu Glu Arg Thr Glu Ile Leu Asn Gln Glu Trp Lys Gln Arg Arg 
    50                  55                  60


Ile Gln Pro Val His Ile Leu Thr Ser Val Ser Ser Leu Arg Gly Thr 
65                  70                  75                  80


Arg Glu Cys Ser Val Thr Ser Asp Leu Asp Phe Pro Thr Gln Val Ile 
                85                  90                  95


Pro Leu Lys Thr Leu Asn Ala Val Ala Ser Val Pro Ile Met Tyr Ser 
            100                 105                 110


Trp Ser Pro Leu Gln Gln Asn Phe Met Val Glu Asp Glu Thr Val Leu 
        115                 120                 125


His Asn Ile Pro Tyr Met Gly Asp Glu Val Leu Asp Gln Asp Gly Thr 
    130                 135                 140


Phe Ile Glu Glu Leu Ile Lys Asn Tyr Asp Gly Lys Val His Gly Asp 
145                 150                 155                 160


Arg Glu Cys Gly Phe Ile Asn Asp Glu Ile Phe Val Glu Leu Val Asn 
                165                 170                 175


Ala Leu Gly Gln Tyr Asn Asp Asp Asp Asp Asp Asp Asp Gly Asp Asp 
            180                 185                 190


Pro Glu Glu Arg Glu Glu Lys Gln Lys Asp Leu Glu Asp His Arg Asp 
        195                 200                 205


Asp Lys Glu Ser Arg Pro Pro Arg Lys Phe Pro Ser Asp Lys Ile Phe 
    210                 215                 220


Glu Ala Ile Ser Ser Met Phe Pro Asp Lys Gly Thr Ala Glu Glu Leu 
225                 230                 235                 240


Lys Glu Lys Tyr Lys Glu Leu Thr Glu Gln Gln Leu Pro Gly Ala Leu 
                245                 250                 255


Pro Pro Glu Cys Thr Pro Asn Ile Asp Gly Pro Asn Ala Lys Ser Val 
            260                 265                 270


Gln Arg Glu Gln Ser Leu His Ser Phe His Thr Leu Phe Cys Arg Arg 
        275                 280                 285


Cys Phe Lys Tyr Asp Cys Phe Leu His Pro Phe His Ala Thr Pro Asn 
    290                 295                 300


Thr Tyr Lys Arg Lys Asn Thr Glu Thr Ala Leu Asp Asn Lys Pro Cys 
305                 310                 315                 320


Gly Pro Gln Cys Tyr Gln His Leu Pro Leu Leu Pro Arg Asn 
                325                 330


<210>  5464
<211>  2904
<212>  DNA
<213>  Homo sapiens

<400>  5464
acctatcctc cccgcctccc gtccgcggcg ggctccgggc ccccgcgatg tctcccggtc     60

cccgcgtgcc tgcacaccgc cttcctgaga ggcgccgtgt gttcagcgaa agaacaaaga    120

gacggcggcg gcgcttccac acggccagtg gcgtccctta cagcgaaccc cgccgccgcc    180

cgcgcgcgca cgcgctgcca gtgcccgccc gcccacgagc cctgagcgca ctctgcgtgg    240

ggctggctcg gcgcctccga gcccggcggg ccctgtgatt ggacgggcgc ccgcctcgcg    300

tcccgccaat cggggcggcg cttgattggg ctgggggggc caaataaaag cgatggcgat    360

tgggctgccg cgtttggcgc tcggtccggt cgcgtccgac acccggtggg actcagaagg    420

cagtggagcc ccggcggcgg cggcggcggc gcgcgggggc gacgcgcggg aacaacgcga    480

gtcggcgcgc gggacgaaga ataatcatgg gccagactgg gaagaaatct gagaagggac    540

cagtttgttg gcggaagcgt gtaaaatcag agtacatgcg actgagacag ctcaagaggt    600

tcagacgagc tgatgaagta aagagtatgt ttagttccaa tcgtcagaaa attttggaaa    660

gaacggaaat cttaaaccaa gaatggaaac agcgaaggat acagcctgtg cacatcctga    720

cttctgtgag ctcattgcgc gggactaggg aggtggaaga tgaaactgtt ttacataaca    780

ttccttatat gggagatgaa gttttagatc aggatggtac tttcattgaa gaactaataa    840

aaaattatga tgggaaagta cacggggata gagaatgtgg gtttataaat gatgaaattt    900

ttgtggagtt ggtgaatgcc cttggtcaat ataatgatga tgacgatgat gatgatggag    960

acgatcctga agaaagagaa gaaaagcaga aagatctgga ggatcaccga gatgataaag   1020

aaagccgccc acctcggaaa tttccttctg ataaaatttt tgaagccatt tcctcaatgt   1080

ttccagataa gggcacagca gaagaactaa aggaaaaata taaagaactc accgaacagc   1140

agctcccagg cgcacttcct cctgaatgta cccccaacat agatggacca aatgctaaat   1200

ctgttcagag agagcaaagc ttacactcct ttcatacgct tttctgtagg cgatgtttta   1260

aatatgactg cttcctacat ccttttcatg caacacccaa cacttataag cggaagaaca   1320

cagaaacagc tctagacaac aaaccttgtg gaccacagtg ttaccagcat ttggagggag   1380

caaaggagtt tgctgctgct ctcaccgctg agcggataaa gaccccacca aaacgtccag   1440

gaggccgcag aagaggacgg cttcccaata acagtagcag gcccagcacc cccaccatta   1500

atgtgctgga atcaaaggat acagacagtg atagggaagc agggactgaa acggggggag   1560

agaacaatga taaagaagaa gaagagaaga aagatgaaac ttcgagctcc tctgaagcaa   1620

attctcggtg tcaaacacca ataaagatga agccaaatat tgaacctcct gagaatgtgg   1680

agtggagtgg tgctgaagcc tcaatgttta gagtcctcat tggcacttac tatgacaatt   1740

tctgtgccat tgctaggtta attgggacca aaacatgtag acaggtgtat gagtttagag   1800

tcaaagaatc tagcatcata gctccagctc ccgctgagga tgtggatact cctccaagga   1860

aaaagaagag gaaacaccgg ttgtgggctg cacactgcag aaagatacag ctgaaaaagg   1920

acggctcctc taaccatgtt tacaactatc aaccctgtga tcatccacgg cagccttgtg   1980

acagttcgtg cccttgtgtg atagcacaaa atttttgtga aaagttttgt caatgtagtt   2040

cagagtgtca aaaccgcttt ccgggatgcc gctgcaaagc acagtgcaac accaagcagt   2100

gcccgtgcta cctggctgtc cgagagtgtg accctgacct ctgtcttact tgtggagccg   2160

ctgaccattg ggacagtaaa aatgtgtcct gcaagaactg cagtattcag cggggctcca   2220

aaaagcatct attgctggca ccatctgacg tggcaggctg ggggattttt atcaaagatc   2280

ctgtgcagaa aaatgaattc atctcagaat actgtggaga gattatttct caagatgaag   2340

ctgacagaag agggaaagtg tatgataaat acatgtgcag ctttctgttc aacttgaaca   2400

atgattttgt ggtggatgca acccgcaagg gtaacaaaat tcgttttgca aatcattcgg   2460

taaatccaaa ctgctatgca aaagttatga tggttaacgg tgatcacagg ataggtattt   2520

ttgccaagag agccatccag actggcgaag agctgttttt tgattacaga tacagccagg   2580

ctgatgccct gaagtatgtc ggcatcgaaa gagaaatgga aatcccttga catctgctac   2640

ctcctccccc ctcctctgaa acagctgcct tagcttcagg aacctcgagt actgtgggca   2700

atttagaaaa agaacatgca gtttgaaatt ctgaatttgc aaagtactgt aagaataatt   2760

tatagtaatg agtttaaaaa tcaacttttt attgccttct caccagctgc aaagtgtttt   2820

gtaccagtga atttttgcaa taatgcagta tggtacattt ttcaactttg aataaagaat   2880

acttgaactt gtccttgttg aatc                                          2904


<210>  5465
<211>  707
<212>  PRT
<213>  Homo sapiens

<400>  5465

Met Gly Gln Thr Gly Lys Lys Ser Glu Lys Gly Pro Val Cys Trp Arg 
1               5                   10                  15


Lys Arg Val Lys Ser Glu Tyr Met Arg Leu Arg Gln Leu Lys Arg Phe 
            20                  25                  30


Arg Arg Ala Asp Glu Val Lys Ser Met Phe Ser Ser Asn Arg Gln Lys 
        35                  40                  45


Ile Leu Glu Arg Thr Glu Ile Leu Asn Gln Glu Trp Lys Gln Arg Arg 
    50                  55                  60


Ile Gln Pro Val His Ile Leu Thr Ser Val Ser Ser Leu Arg Gly Thr 
65                  70                  75                  80


Arg Glu Val Glu Asp Glu Thr Val Leu His Asn Ile Pro Tyr Met Gly 
                85                  90                  95


Asp Glu Val Leu Asp Gln Asp Gly Thr Phe Ile Glu Glu Leu Ile Lys 
            100                 105                 110


Asn Tyr Asp Gly Lys Val His Gly Asp Arg Glu Cys Gly Phe Ile Asn 
        115                 120                 125


Asp Glu Ile Phe Val Glu Leu Val Asn Ala Leu Gly Gln Tyr Asn Asp 
    130                 135                 140


Asp Asp Asp Asp Asp Asp Gly Asp Asp Pro Glu Glu Arg Glu Glu Lys 
145                 150                 155                 160


Gln Lys Asp Leu Glu Asp His Arg Asp Asp Lys Glu Ser Arg Pro Pro 
                165                 170                 175


Arg Lys Phe Pro Ser Asp Lys Ile Phe Glu Ala Ile Ser Ser Met Phe 
            180                 185                 190


Pro Asp Lys Gly Thr Ala Glu Glu Leu Lys Glu Lys Tyr Lys Glu Leu 
        195                 200                 205


Thr Glu Gln Gln Leu Pro Gly Ala Leu Pro Pro Glu Cys Thr Pro Asn 
    210                 215                 220


Ile Asp Gly Pro Asn Ala Lys Ser Val Gln Arg Glu Gln Ser Leu His 
225                 230                 235                 240


Ser Phe His Thr Leu Phe Cys Arg Arg Cys Phe Lys Tyr Asp Cys Phe 
                245                 250                 255


Leu His Pro Phe His Ala Thr Pro Asn Thr Tyr Lys Arg Lys Asn Thr 
            260                 265                 270


Glu Thr Ala Leu Asp Asn Lys Pro Cys Gly Pro Gln Cys Tyr Gln His 
        275                 280                 285


Leu Glu Gly Ala Lys Glu Phe Ala Ala Ala Leu Thr Ala Glu Arg Ile 
    290                 295                 300


Lys Thr Pro Pro Lys Arg Pro Gly Gly Arg Arg Arg Gly Arg Leu Pro 
305                 310                 315                 320


Asn Asn Ser Ser Arg Pro Ser Thr Pro Thr Ile Asn Val Leu Glu Ser 
                325                 330                 335


Lys Asp Thr Asp Ser Asp Arg Glu Ala Gly Thr Glu Thr Gly Gly Glu 
            340                 345                 350


Asn Asn Asp Lys Glu Glu Glu Glu Lys Lys Asp Glu Thr Ser Ser Ser 
        355                 360                 365


Ser Glu Ala Asn Ser Arg Cys Gln Thr Pro Ile Lys Met Lys Pro Asn 
    370                 375                 380


Ile Glu Pro Pro Glu Asn Val Glu Trp Ser Gly Ala Glu Ala Ser Met 
385                 390                 395                 400


Phe Arg Val Leu Ile Gly Thr Tyr Tyr Asp Asn Phe Cys Ala Ile Ala 
                405                 410                 415


Arg Leu Ile Gly Thr Lys Thr Cys Arg Gln Val Tyr Glu Phe Arg Val 
            420                 425                 430


Lys Glu Ser Ser Ile Ile Ala Pro Ala Pro Ala Glu Asp Val Asp Thr 
        435                 440                 445


Pro Pro Arg Lys Lys Lys Arg Lys His Arg Leu Trp Ala Ala His Cys 
    450                 455                 460


Arg Lys Ile Gln Leu Lys Lys Asp Gly Ser Ser Asn His Val Tyr Asn 
465                 470                 475                 480


Tyr Gln Pro Cys Asp His Pro Arg Gln Pro Cys Asp Ser Ser Cys Pro 
                485                 490                 495


Cys Val Ile Ala Gln Asn Phe Cys Glu Lys Phe Cys Gln Cys Ser Ser 
            500                 505                 510


Glu Cys Gln Asn Arg Phe Pro Gly Cys Arg Cys Lys Ala Gln Cys Asn 
        515                 520                 525


Thr Lys Gln Cys Pro Cys Tyr Leu Ala Val Arg Glu Cys Asp Pro Asp 
    530                 535                 540


Leu Cys Leu Thr Cys Gly Ala Ala Asp His Trp Asp Ser Lys Asn Val 
545                 550                 555                 560


Ser Cys Lys Asn Cys Ser Ile Gln Arg Gly Ser Lys Lys His Leu Leu 
                565                 570                 575


Leu Ala Pro Ser Asp Val Ala Gly Trp Gly Ile Phe Ile Lys Asp Pro 
            580                 585                 590


Val Gln Lys Asn Glu Phe Ile Ser Glu Tyr Cys Gly Glu Ile Ile Ser 
        595                 600                 605


Gln Asp Glu Ala Asp Arg Arg Gly Lys Val Tyr Asp Lys Tyr Met Cys 
    610                 615                 620


Ser Phe Leu Phe Asn Leu Asn Asn Asp Phe Val Val Asp Ala Thr Arg 
625                 630                 635                 640


Lys Gly Asn Lys Ile Arg Phe Ala Asn His Ser Val Asn Pro Asn Cys 
                645                 650                 655


Tyr Ala Lys Val Met Met Val Asn Gly Asp His Arg Ile Gly Ile Phe 
            660                 665                 670


Ala Lys Arg Ala Ile Gln Thr Gly Glu Glu Leu Phe Phe Asp Tyr Arg 
        675                 680                 685


Tyr Ser Gln Ala Asp Ala Leu Lys Tyr Val Gly Ile Glu Arg Glu Met 
    690                 695                 700


Glu Ile Pro 
705


<210>  5466
<211>  580
<212>  DNA
<213>  Homo sapiens

<400>  5466
tatgcaaaag gtaggtacct ttgacgtgag aattggaact cccttttcag tcctgtgatg     60

atggacttga atacttctgg gatagttgtt tgttatgtga acaagtcagt taaccccccg    120

tggcccgtct tcatgctcac tgacaccagt gtgtctcttt gcagttatga tggttaacgg    180

tgatcacagg ataggtattt ttgccaagag agccatccag actggcgaag agctgttttt    240

tgattacaga tacagccagg ctgatgccct gaagtatgtc ggcatcgaaa gagaaatgga    300

aatcccttga catctgctac ctcctccccc ctcctctgaa acagctgcct tagcttcagg    360

aacctcgagt actgtgggca atttagaaaa agaacatgca gtttgaaatt ctgaatttgc    420

aaagtactgt aagaataatt tatagtaatg agtttaaaaa tcaacttttt attgccttct    480

caccagctgc aaagtgtttt gtaccagtga atttttgcaa taatgcagta tggtacattt    540

ttcaactttg aataaagaat acttgaactt gtccttgttg                          580


<210>  5467
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  5467

Met Met Val Asn Gly Asp His Arg Ile Gly Ile Phe Ala Lys Arg Ala 
1               5                   10                  15


Ile Gln Thr Gly Glu Glu Leu Phe Phe Asp Tyr Arg Tyr Ser Gln Ala 
            20                  25                  30


Asp Ala Leu Lys Tyr Val Gly Ile Glu Arg Glu Met Glu Ile Pro 
        35                  40                  45


<210>  5468
<211>  1080
<212>  DNA
<213>  Homo sapiens

<400>  5468
actgcatttg caaccatctt ccagactccc ctggatattc tcaaaggact gagaggaaag     60

gcagctgctt tcatagctga tgttctgggg tagaatgtaa ggctgtgtag ggatgtttct    120

ggtgggatta tgtgaaaatg gaggtaggct taacatgtaa gatattcaga gaaactctta    180

gttggaacaa gtagaatagg tttttttcta tgaatgcttt atagacatta taatgaaaaa    240

aactaatttt aaatgtgaaa atgcctattc gtgatgtttg gaagaatttt gtcagatttt    300

tttttttttt tgctatgttt tgctcagtaa tgtatgttta tagttgataa ttaatagctt    360

ttgagtcaga taaccatctt gaattatagg tgattaattt taacctggaa caatagtgtg    420

ttcttccaaa tgtcatttct tactgaatga agctgcttga tttatttgct tttgcaggca    480

aaccctgaag aactgtaacc agttgcattt acaaaatcat aataacttgg tttacttata    540

actgaaatta ttcactgggc tgtgcttact tttttctttt tagattttgt ggtggatgca    600

acccgcaagg gtaacaaaat tcgttttgca aatcattcgg taaatccaaa ctgctatgca    660

aaagttatga tggttaacgg tgatcacagg ataggtattt ttgccaagag agccatccag    720

actggcgaag agctgttttt tgattacaga tacagccagg ctgatgccct gaagtatgtc    780

ggcatcgaaa gagaaatgga aatcccttga catctgctac ctcctccccc ctcctctgaa    840

acagctgcct tagcttcagg aacctcgagt actgtgggca atttagaaaa agaacatgca    900

gtttgaaatt ctgaatttgc aaagtactgt aagaataatt tatagtaatg agtttaaaaa    960

tcaacttttt attgccttct caccagctgc aaagtgtttt gtaccagtga atttttgcaa   1020

taatgcagta tggtacattt ttcaactttg aataaagaat acttgaactt gtccttgttg   1080


<210>  5469
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  5469

Met Met Val Asn Gly Asp His Arg Ile Gly Ile Phe Ala Lys Arg Ala 
1               5                   10                  15


Ile Gln Thr Gly Glu Glu Leu Phe Phe Asp Tyr Arg Tyr Ser Gln Ala 
            20                  25                  30


Asp Ala Leu Lys Tyr Val Gly Ile Glu Arg Glu Met Glu Ile Pro 
        35                  40                  45


<210>  5470
<211>  1199
<212>  DNA
<213>  Homo sapiens

<400>  5470
tgaggattta cagtgatagc ttttgttttc attctgtagt ctactttgtc cccagtccat     60

tttcaccctc cttttttgat gatgtgattg tgttttattc tctagcatct attgctggca    120

ccatctgacg tggcaggctg ggggattttt atcaaagatc ctgtgcagaa aaatgaattc    180

atctcagaat actgtggaga gattatttct caagatgaag ctgacagaag agggaaagtg    240

tatgataaat acatgtgcag ctttctgttc aacttgaaca atggtatgtt tcagagctgg    300

gaggcagtga gttcctgagt tgcatgtggc agccttctgc cggccgagtg ttcagaaacg    360

agggtagagg tcagtgaggt gaccagaagg aggatctcct tagaggcatg gggggctgct    420

tgcttgaaag gaactggagc aaggaattcc tcagggagca gatagactag atgtgcagga    480

aaccgcctct ctggagtccc ggctgtctgt gggtggcact atcccagcat ctggctgtga    540

aggggacgtt gtgctcttgc tgctcacctc acctcttgtg ttcaggcagc tcagcacacc    600

tcctccagtc agtgcctctg agcggggaag gaggggagga gcactgcatt tgcaaccatc    660

ttccagactc ccctggatat tctcaaagga ctgagaggaa aggcagctgc tttcatagct    720

gatgttctgg ggtagaatgt aaggctgtgt agggatgttt ctggtgggat tatgtgaaaa    780

tggaggtagg cttaacatgt aagatattca gagaaactct tagttggaac aagtagaata    840

ggtttttttc tatgaatgct ttatagacat tataatgaaa aaaactaatt ttaaatgtga    900

aaatgcctat tcgtgatgtt tggaagaatt ttgtcagatt tttttttttt tttgctatgt    960

tttgctcagt aatgtatgtt tatagttgat aattaatagc ttttgagtca gataaccatc   1020

ttgaattata ggtgattaat tttaacctgg aacaatagtg tgttcttcca aatgtcattt   1080

cttactgaat gaagctgctt gatttatttg cttttgcagg caaaccctga agaactgtaa   1140

ccagttgcat ttacaaaatc ataataactt ggtttactta taactgaaat tattcactg    1199


<210>  5471
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  5471

Met Asn Ser Ser Gln Asn Thr Val Glu Arg Leu Phe Leu Lys Met Lys 
1               5                   10                  15


Leu Thr Glu Glu Gly Lys Cys Met Ile Asn Thr Cys Ala Ala Phe Cys 
            20                  25                  30


Ser Thr 



<210>  5472
<211>  537
<212>  DNA
<213>  Homo sapiens

<400>  5472
attgggcggg ggggtggtat gtgtatatgt tggggaggga gcagctttgg ggtgtttcct     60

caaattctct aattggggga cccctgcaaa agagtgtcac taagaagaaa ggtattgggt    120

tggtgcaaaa gtaattgctg tttttaccat taaaagtaat ggcaaaactg taattacttt    180

tgcatcaacc taatatcttg ataatctggg atggaataag agtaggtggc agctgcagca    240

tgggcactcc caaaggctcc aagaggtacc cagagcaggg aggtgcattg cagcagagca    300

gttggaacag cctggactct gacccgagag gagtgtggaa cgaaccctgg aactccagca    360

gttctggagg ctacaagatg gaatcaaggt gtcagcaagg ttgcccttcc tccgaagact    420

ctacagaaga atcttctagc ttctgctggc agctggtgac ccctggcaat ccttggattg    480

tgacaggatc actttaatct cacgccttgc cttcacttgg attttttccc tgtttgt       537


<210>  5473
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  5473

Met Gly Thr Pro Lys Gly Ser Lys Arg Tyr Pro Glu Gln Gly Gly Ala 
1               5                   10                  15


Leu Gln Gln Ser Ser Trp Asn Ser Leu Asp Ser Asp Pro Arg Gly Val 
            20                  25                  30


Trp Asn Glu Pro Trp Asn Ser Ser Ser Ser Gly Gly Tyr Lys Met Glu 
        35                  40                  45


Ser Arg Cys Gln Gln Gly Cys Pro Ser Ser Glu Asp Ser Thr Glu Glu 
    50                  55                  60


Ser Ser Ser Phe Cys Trp Gln Leu Val Thr Pro Gly Asn Pro Trp Ile 
65                  70                  75                  80


Val Thr Gly Ser Leu 
                85


<210>  5474
<211>  896
<212>  DNA
<213>  Homo sapiens

<400>  5474
cccaaagtac ttgtgtccgg gtggtggact ggattagctg cggagccctg gaagctgcct     60

gtccttctcc ctgtgcttaa ccagaggtgc ccatgggttg gacaatgagg ctggtcacag    120

cagcactgtt actgggtctc atgatggtgg tcactggaga cgaggatgag aacagcccgt    180

gtgcccatga ggccctcttg gacgaggaca ccctcttttg ccagggcctt gaagttttct    240

acccagagtt ggggaacatt ggctgcaagg ttgttcctga ttgtaacaac tacagacaga    300

agatcacctc ctggatggag ccgatagtca agttcccggg ggccgtggac ggcgcaacct    360

atatcctggt gatggtggat ccagatgccc ctagcagagc agaacccaga cagagattct    420

ggagacattg gctggtaaca gatatcaagg gcgccgacct gaagaaaggg aagattcagg    480

gccaggagtt atcagcctac caggctccct ccccaccggc acacagtggc ttccatcgct    540

accagttctt tgtctatctt caggaaggaa aagtcatctc tctccttccc aaggaaaaca    600

aaactcgagg ctcttggaaa atggacagat ttctgaaccg tttccacctg ggcgaacctg    660

aagcaagcac ccagttcatg acccagaact accaggactc accaaccctc caggctccca    720

gagaaagggc cagcgagccc aagcacaaaa accaggcgga gatagctgcc tgctagatag    780

ccggctttgc catccgggca tgtggccaca ctgcccacca ccgacgatgt gggtatggaa    840

ccccctctgg atacagaacc ccttcttttc caaataaaaa aaaaatcatc cagggc        896


<210>  5475
<211>  227
<212>  PRT
<213>  Homo sapiens

<400>  5475

Met Gly Trp Thr Met Arg Leu Val Thr Ala Ala Leu Leu Leu Gly Leu 
1               5                   10                  15


Met Met Val Val Thr Gly Asp Glu Asp Glu Asn Ser Pro Cys Ala His 
            20                  25                  30


Glu Ala Leu Leu Asp Glu Asp Thr Leu Phe Cys Gln Gly Leu Glu Val 
        35                  40                  45


Phe Tyr Pro Glu Leu Gly Asn Ile Gly Cys Lys Val Val Pro Asp Cys 
    50                  55                  60


Asn Asn Tyr Arg Gln Lys Ile Thr Ser Trp Met Glu Pro Ile Val Lys 
65                  70                  75                  80


Phe Pro Gly Ala Val Asp Gly Ala Thr Tyr Ile Leu Val Met Val Asp 
                85                  90                  95


Pro Asp Ala Pro Ser Arg Ala Glu Pro Arg Gln Arg Phe Trp Arg His 
            100                 105                 110


Trp Leu Val Thr Asp Ile Lys Gly Ala Asp Leu Lys Lys Gly Lys Ile 
        115                 120                 125


Gln Gly Gln Glu Leu Ser Ala Tyr Gln Ala Pro Ser Pro Pro Ala His 
    130                 135                 140


Ser Gly Phe His Arg Tyr Gln Phe Phe Val Tyr Leu Gln Glu Gly Lys 
145                 150                 155                 160


Val Ile Ser Leu Leu Pro Lys Glu Asn Lys Thr Arg Gly Ser Trp Lys 
                165                 170                 175


Met Asp Arg Phe Leu Asn Arg Phe His Leu Gly Glu Pro Glu Ala Ser 
            180                 185                 190


Thr Gln Phe Met Thr Gln Asn Tyr Gln Asp Ser Pro Thr Leu Gln Ala 
        195                 200                 205


Pro Arg Glu Arg Ala Ser Glu Pro Lys His Lys Asn Gln Ala Glu Ile 
    210                 215                 220


Ala Ala Cys 
225


<210>  5476
<211>  475
<212>  DNA
<213>  Homo sapiens

<400>  5476
ccttcttttc ctgcactcta gtgtcccttc tgcctgactc tctgtgcatc ttgaaaggag     60

aaacggtgcc catgggttgg acaatgaggc tggtcacagc agcactgtta ctgggtctca    120

tgatggtggt cactggagac gaggatgaga acagcccgtg tgcccatgag gccctcttgg    180

acgaggacac cctcttttgc cagggccttg aagttttcta cccagagttg gggaacattg    240

gctgcaaggt tgttcctgat tgtaacaact acagacagaa gatcacctcc tggatggagc    300

cgatagtcaa gttcccgggg gccgtggacg gcgcaaccta tatcctggtg atggtggatc    360

cagatgcccc tagcagagca gaacccagac agagattctg gagacattgg ctggtaacag    420

atatcaagat ggggaaagca gagcccagag aagttgaatg atgccatctc ttagc         475


<210>  5477
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  5477

Met Gly Trp Thr Met Arg Leu Val Thr Ala Ala Leu Leu Leu Gly Leu 
1               5                   10                  15


Met Met Val Val Thr Gly Asp Glu Asp Glu Asn Ser Pro Cys Ala His 
            20                  25                  30


Glu Ala Leu Leu Asp Glu Asp Thr Leu Phe Cys Gln Gly Leu Glu Val 
        35                  40                  45


Phe Tyr Pro Glu Leu Gly Asn Ile Gly Cys Lys Val Val Pro Asp Cys 
    50                  55                  60


Asn Asn Tyr Arg Gln Lys Ile Thr Ser Trp Met Glu Pro Ile Val Lys 
65                  70                  75                  80


Phe Pro Gly Ala Val Asp Gly Ala Thr Tyr Ile Leu Val Met Val Asp 
                85                  90                  95


Pro Asp Ala Pro Ser Arg Ala Glu Pro Arg Gln Arg Phe Trp Arg His 
            100                 105                 110


Trp Leu Val Thr Asp Ile Lys Met Gly Lys Ala Glu Pro Arg Glu Val 
        115                 120                 125


Glu 



<210>  5478
<211>  444
<212>  DNA
<213>  Homo sapiens

<400>  5478
aggccatggt agatgtgggc agggaactgg agactccggg cccagtgggt tcaacctcat     60

gagggagtgg agttgagatg ctttggggat cagtgacaca acctcttact tggcttgggg    120

tgcaaaccta gactccctgt caccctggcc ttctcctctc caagagaagg agaactgtgg    180

gcatcgcagt ggtgacactt cagttatcac aggctcagca gccaagtgaa aagatgatgt    240

tggaatttcc tagatgattc cattcatgga ttggccatgc agcagtcctt agggatcccc    300

tcctaaaagt cacgatctac ccaagaatcc actgtgaatc gaccatccgc cagtttctcc    360

aaacgtttta aagagcaatt tgtattttca acctgtctca cctcttgggg ataatgaatt    420

agacgagttg actacccact gtgt                                           444


<210>  5479
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  5479

Phe His Ser Trp Ile Gly His Ala Ala Val Leu Arg Asp Pro Leu Leu 
1               5                   10                  15


Lys Val Thr Ile Tyr Pro Arg Ile His Cys Glu Ser Thr Ile Arg Gln 
            20                  25                  30


Phe Leu Gln Thr Phe 
        35


<210>  5480
<211>  853
<212>  DNA
<213>  Homo sapiens

<400>  5480
ggttactttc tcagctgtaa ccaggaggca gggaagaagg caatgcagtc ctcattcttt     60

agagactcaa cctgtgtccc cagccctccc cacctcctcc cacacccccc tccaaactca    120

gcttggctgg gaaaggaaac tccccagtct gctgtgctcc tgcaagctga gtgtttgcag    180

gtgaatctac tccaggccgt gagcgcccca gaggtgggaa ctatatctta gtcacccttg    240

tactttcaag cctcacaatg ggacctgccg aaaaaagggc actcagtaaa cgtcttgtga    300

acgcatgaat tgggcagctg ttggtgtacg tgttttgttt ctgatgctga gacccttcct    360

gaaccggatc tccatccctt cactgagcag ggttcacaca tatttatgtt ggagtgcaaa    420

ggcttccgat gcccggacac gtgtcctcca atctgagaag ggaaccaggg aaggggctgg    480

agttgatgca tcttgactta agggctgaag agttggcaat tttggaggcc agtgaagagc    540

cacgtagaaa atgtcccgct gcctgccatc atcagcagct cctcttgctc ccatcctgca    600

gagagggctc ccacacagag agcagacaca gggacctctt taaaatgaag atgaaatgca    660

cctggttcta ccacctagtt agaagcagtt atgaaggttg aagagctgtt atctgagatt    720

tatagcccca aatctatgag atagactctc ctaattaata agacaaggat gactagaaag    780

ttgtgaaaac tacctggcag ggcttggagc ctgctgtcac caccacgatg atagcactgt    840

ctttgctgct gag                                                       853


<210>  5481
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  5481

Met Asn Trp Ala Ala Val Gly Val Arg Val Leu Phe Leu Met Leu Arg 
1               5                   10                  15


Pro Phe Leu Asn Arg Ile Ser Ile Pro Ser Leu Ser Arg Val His Thr 
            20                  25                  30


Tyr Leu Cys Trp Ser Ala Lys Ala Ser Asp Ala Arg Thr Arg Val Leu 
        35                  40                  45


Gln Ser Glu Lys Gly Thr Arg Glu Gly Ala Gly Val Asp Ala Ser 
    50                  55                  60


<210>  5482
<211>  3879
<212>  DNA
<213>  Homo sapiens

<400>  5482
agctgtaacc aggaggcagg gaagaaggca atgcagtcct cattctttag agactcaacc     60

tgtgtcccca gccctcccca cctcctccca cacccccctc caaactcagc ttggctggga    120

aaggaaactc cccagtctgc tgtgctcctg caagctgagt gtttgcaggg cagctgttgg    180

tgtacgtgtt ttgtttctga tgctgagacc cttcctgaac cggatctcca tcccttcact    240

gagcagggtt cacacatatt tatgttggag tgcaaaggct tccgatgccc ggacacgtgt    300

cctccaatct gagaagggaa ccagggaagg ggctggagtt gatgcatctt gacttaaggg    360

ctgaagagtt ggcaattttg gaggccagtg aagagccacg tagaaaatgt cccgctgcct    420

gccatcatca gcagctcctc ttgctcccat cctgcagaga gggctcccac acagagagca    480

gacacaggga cctctttaaa atgaagatga aatgcacctg gttctaccac ctagttagaa    540

gcagttatga aggttgaaga gctgttatct gagatttata gccccaaatc tatgagatag    600

actctcctaa ttaataagac aaggatgact agaaagttgt gaaaactacc tggcagggct    660

tggagcctgc tgtcaccacc acgatgatag cactgtcttt gctgctgagc ctattagaat    720

gtcaggatgt gcattcttct ctcctagtgg gatggcacgg ttcacctggc tattacagag    780

aagcaagtgc agatcgtgac ttaaggctcc gggaggagag ttaatcaggg aagagctggt    840

tgacaagact cactcagtgc atgacttgag agcaccaaga gggggaaagg gagaagaaag    900

aacctcttcc aaaggcagca tccaccccct tgacaaaggg ccatttcccc cagcccgggg    960

tgctttctga cttcctttgt tccccgatga gcattttctt ccttgtcccc agccttcaca   1020

taagttcaat tcaacatcct ctctctcttc tcccaatgtc ctctccttaa ttttgctgca   1080

tcctccaatg tgaatgtttg cctcctggtc tgggatctgt cttattccct ttatctcacc   1140

tgaaaaaact ctccccttta atctctgctc attcaagtcc tgcccatcct tcaaagtatg   1200

gccaagctca cctcttccag aaagccccac cctgtggtgt tatctccatc ctgaatcaca   1260

gcagcactta ctgtgagata actatcaggt tacatctatc agagttcaat gcactctccc   1320

caaatgaagt ggacacttgt tggcagtaag aagagaagct ttttgcacca agtggtgcat   1380

tcaatgcaat gcaaggagac tgtgacgata ctgaaatgag tattacccgg ccccaggaga   1440

tgaacaccgt ccttgcttga tgccagttca taaagagagc tcttgtttat tgagagctta   1500

tgagtgctga ggaattcaca taaatcatct catctaaatt ttccaacaat catgagatgg   1560

tttctcttat ttcctccttt tacgcatgaa gaaactgggg ctcaggaggt tagatgactt   1620

tctcagagtc acacagatag tacagggctg acccagaatt caagcccagg tctggcagac   1680

tccagcaccc gccctttgcc tccacgacca agtacaagca gcaggctggc actggccttt   1740

ccctgctatg actgccgagc tgggttacac ctgctgctgg tccccagcac caggcacacg   1800

acgtaactgt gagtcctccg agtatgtgag ggagctggca ctcaccttct gcctgaagca   1860

aaggagctgt gctcttccgt ttcagtgtga aaaagcctca gaagatgccc agcttagaag   1920

gacacaagag acagtctgtg gacaacatct ccacttcctg gcgtcctcag cactgttgct   1980

agtgaagcta ctctgcccaa ggtctccaga gagcttctga aagaagtcag gactcatgca   2040

tgcagatgaa tacgcctcgt gggtattcac caggtcctct tgggaagcca gctctgtgtc   2100

ccaggcacac cgtctgtgtg caagagaagg ggagcacctg agtttgggaa ctgctttcgt   2160

accagcttat aggccacccc aagaaccggc ctcctggctt cctagtcaca gaccgcctgc   2220

agggttgact tatgcatcct tttgcaggag acaggctcac ttctctcctg tgactaacat   2280

ggaattacgg gttaaggagg gaagttgtac tcacctgttg attcatttat tcactcactt   2340

gctcactcat caatcatttc ttcaacaatg aaacccttac tagacaaata ctgactccct   2400

gctccagaat aactatctgt tcggtgctag gactgtcaaa tgagtaagcg tttcttccca   2460

caggcgttca gggtctattt ctgcacttta cagacaggca agacagaagt gatcagaagc   2520

ggccaccaac catggagttc agaaacacgg cacagttctg gaagaggcga aaggcggctc   2580

ttccatccat gctggtcaag aggaaattca acacacctca cagccattga atctgaccag   2640

gcgtgtaata catcccatcg tcttgtcagt tagcagctgt gggaccttga aggcttctta   2700

aattccccaa gtctagactt tcttatcttt aaaatgcagc tgaaaacaat gcctgtctca   2760

tggaggtgta agggttaaat ggaatcatgt agcaagcatt cagcacatgt caagtccagg   2820

tcaaggccaa catgcagggg cagggagagg tgtaacctct ttcagtttgg agccatgcag   2880

gaccctgcca tttgcagccc tttggggtaa gactgtagcc cccaaacatc ctgctgcccc   2940

agagcagtgg cccagcaggt gcactgagag ctctggtgca cctggcatgc cccgactcct   3000

cacacagcag caacagggac agtgacaggg acctgagatg gggtggccca cctggctggc   3060

agctggcact gggcacattg cccagaagtt ggggagttct caggtagggg cagaggtggg   3120

tgtttgaggg agcagttagc agcactgtct gctgtggcag gggtctcctg ggtaaggtca   3180

gagggattcg aggaggccca gggatcaccc cagggtgggg tgggacgctg ctcaagtcac   3240

aaagcaaagt tgcagggtgt aggggagggg atgggactgt tagtctaatt gtgactcatc   3300

tctccttatt tttctcctta tctcttgtat ttattttttt caatcctccc aagttactgg   3360

gccttgagga cactcctagt gtgtgtgtgt gtgtgtgtgt gtgtgtatgt gtgtgtgtgt   3420

gtgtatttct atatatataa tttttctttt ttttgagaca gagtttcgct cttgttgctc   3480

aggtggaagt gcaatggtgc gatctcaact cactgcaacc tgcatctcct gggatcgctt   3540

gagcccagga agtcgaggct gcagtgagcc atgatcatat ttgccagcct gggtgacaga   3600

gcaagaccat ctcaaagaac gtatttaccg aatgaagttt tatgatgttc tctagcactt   3660

tttagtttat tgtctttaaa aagaaaccct ctgaagtgtc tctggagaat acaaacgcat   3720

gcgcgcatgc acacgctggg aacaggagct gcttcagtag gtaactgagt gggagggagg   3780

ttagcttttc actgtgaccc ttatctgtac acctgctaac tcaaaataat ttaataacaa   3840

caacaatgac aataaaaagg gagtgagtgc tctcatttt                          3879


<210>  5483
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  5483

Met Gln Ser Ser Phe Phe Arg Asp Ser Thr Cys Val Pro Ser Pro Pro 
1               5                   10                  15


His Leu Leu Pro His Pro Pro Pro Asn Ser Ala Trp Leu Gly Lys Glu 
            20                  25                  30


Thr Pro Gln Ser Ala Val Leu Leu Gln Ala Glu Cys Leu Gln Gly Ser 
        35                  40                  45


Cys Trp Cys Thr Cys Phe Val Ser Asp Ala Glu Thr Leu Pro Glu Pro 
    50                  55                  60


Asp Leu His Pro Phe Thr Glu Gln Gly Ser His Ile Phe Met Leu Glu 
65                  70                  75                  80


Cys Lys Gly Phe Arg Cys Pro Asp Thr Cys Pro Pro Ile 
                85                  90


<210>  5484
<211>  559
<212>  DNA
<213>  Homo sapiens

<400>  5484
ccaaagtact tgtgtccggg tggtggactg gattagctgc ggagccctgg aagctgcctg     60

tccttctccc tgtgcttaac cagaggtgcc catgggttgg acaatgaggc tggtcacagc    120

agcactgtta ctgggtctca tgatggtggt cactggagac gaggatgaga acagcccgtg    180

tgcccatgag gccctcttgg acgaggacac cctcttttgc cagggccttg aagttttcta    240

cccagagttg gggaacattg gctgcaaggt tgttcctgat tgtaacaact acagacagaa    300

gatcacctcc tggatggagc cgatagtcaa gttcccgggg gccgtggacg tgagtgatgc    360

ctgggacaca gagctggctt cccaagagga cctggtgaat acccacgagg cgtattcatc    420

tgcatgcatg agtcctgact tctttcagaa gctctctgga gaccttgggc agagtagctt    480

cactagcaac agtgctgagg acgccaggaa gtggagatgt tgtccacaga ctgtctcttg    540

tgtccttcta agctgggca                                                 559


<210>  5485
<211>  155
<212>  PRT
<213>  Homo sapiens

<400>  5485

Met Gly Trp Thr Met Arg Leu Val Thr Ala Ala Leu Leu Leu Gly Leu 
1               5                   10                  15


Met Met Val Val Thr Gly Asp Glu Asp Glu Asn Ser Pro Cys Ala His 
            20                  25                  30


Glu Ala Leu Leu Asp Glu Asp Thr Leu Phe Cys Gln Gly Leu Glu Val 
        35                  40                  45


Phe Tyr Pro Glu Leu Gly Asn Ile Gly Cys Lys Val Val Pro Asp Cys 
    50                  55                  60


Asn Asn Tyr Arg Gln Lys Ile Thr Ser Trp Met Glu Pro Ile Val Lys 
65                  70                  75                  80


Phe Pro Gly Ala Val Asp Val Ser Asp Ala Trp Asp Thr Glu Leu Ala 
                85                  90                  95


Ser Gln Glu Asp Leu Val Asn Thr His Glu Ala Tyr Ser Ser Ala Cys 
            100                 105                 110


Met Ser Pro Asp Phe Phe Gln Lys Leu Ser Gly Asp Leu Gly Gln Ser 
        115                 120                 125


Ser Phe Thr Ser Asn Ser Ala Glu Asp Ala Arg Lys Trp Arg Cys Cys 
    130                 135                 140


Pro Gln Thr Val Ser Cys Val Leu Leu Ser Trp 
145                 150                 155


<210>  5486
<211>  898
<212>  DNA
<213>  Homo sapiens

<400>  5486
gggagacatg gttcatttca tagcatatgg gaaaggctga gggaagagca ggtttaggag     60

atgagtacaa gagctcaggg cctctgatct ggacatgatc ttcatcagat cacactccag    120

ctatgacagt gattgtccaa gctccattcc ctgtctctcc tcccagacta ggacatcttc    180

ttcttctggg ttcccacatc attctaggtt ccagtggcac ttttcttact tgatgcaagg    240

atgtgggatt tgggaacatg gtttcatctc tccaaccaca ataccagcaa ctttcaggca    300

actgtctgat gccacacagc aaatctgccc cagggcagag ggggcagtag gtaggcagta    360

actgggagca caggcagaga ggctggcatg aagaaacctg cccatgggaa gcagggccaa    420

tgccacctag gctgggttca aggatgtggc caaaaaagca gaacttccga caaacttgga    480

aaactagtca ggttactgaa acaggaactt aagcttctca gcaaattaga cgtaacatat    540

aaactggaaa aatcagtgaa cttgaagata gagcaacaga aatgatctaa agaaatataa    600

agagagaaaa gaaggctggg ggacagaaca gagcacccaa gcattgtgag acaacataaa    660

atggtctaac atatgtatag ttgggatctc attaagaaaa gagagcagag tagaactatt    720

tgaagagata atgaccaaga acttgttaaa gaaaggcaac ataccacaag tccaagatac    780

tcagagaacc ttaatcagaa tttttaaaaa aatccaccta gatgtgtcat gatcaaactg    840

ctaaaaacca aagataaatt ctgaagacaa ccaaggaaaa cagaatgccg gtgtcccc      898


<210>  5487
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  5487

Met Ile Phe Ile Arg Ser His Ser Ser Tyr Asp Ser Asp Cys Pro Ser 
1               5                   10                  15


Ser Ile Pro Cys Leu Ser Ser Gln Thr Arg Thr Ser Ser Ser Ser Gly 
            20                  25                  30


Phe Pro His His Ser Arg Phe Gln Trp His Phe Ser Tyr Leu Met Gln 
        35                  40                  45


Gly Cys Gly Ile Trp Glu His Gly Phe Ile Ser Pro Thr Thr Ile Pro 
    50                  55                  60


Ala Thr Phe Arg Gln Leu Ser Asp Ala Thr Gln Gln Ile Cys Pro Arg 
65                  70                  75                  80


Ala Glu Gly Ala Val Gly Arg Gln 
                85


<210>  5488
<211>  2934
<212>  DNA
<213>  Homo sapiens

<400>  5488
caggtcttct tcagccggat gactgtggag cgccaccaca agcagggcct gcaacccagg     60

catccaggct agacaccaaa tcagcaaact ttattcccgc gctgccgagt acaagccggc    120

gcctccccgg cgcacacagt acacatcagc tccgggagac ctacccgacc cgcccctcca    180

gcgccgtccc cgcccccgtt cctgccccac ccctttcccc gcccccggcc cggctcgcct    240

ttctcgcggc gctgcaaccc tcccaccaca gcccatccag ccccgcccag cgcgccgcgg    300

tgcgcatgcg tggaggccct cgctgccgct gagcacctcg ggaagtgtag tctcttcgca    360

ggtgcggctg ggcagctaga gtcctgcatc ccggtggaat ccggagaagt gagaacattc    420

ccgccgcccg gtcctcattc ccatcttccc acctgtccag tcccctcgca ctcccgctgc    480

accccacgcg ccgggcttca gtcagagagt gcactgagga agagcggaga ccccctcttc    540

ccctcagcag gctgtgccgg gggaggcggg gtccaccgcc cgccccccgc cgtcgctctc    600

cccgcctccc cttccctccc ctcctggcgg gtgcggggcc ggtgtccgaa gtcaggcggc    660

ggcccccgca gcggccgcag gaggggcggc tgcggtgggc gccgcgggcg atgcccctgc    720

ccggctgctc cggcgggggg cagtgcgagc ggcggcggcg ggggaggagg cggggggcgg    780

cggctgcggc ggctgcagca gaggggccga gagctggcgg tggcggcggc ggtggtcgtg    840

aagggcatcg gcggcggcgg tgatggcaga gatgatgtga gtgcccgccg gctggagacc    900

tggggccgcg gagcgcggga cgggcggcgg cggcgtgcgg gagcggcccc gggggcggcg    960

gagggatgcg gggagcgcgg gcagagccgg agcggcggcc gccaaccggc cggcagtggc   1020

tggagccccg cgctgcggcg ccgggggagc cgggcccggc gtgggggtcg cgggcggcgg   1080

cggggcggtc aggccgaggg gcgtctgcga ttgttctcaa cacccctccc ccaccccatc   1140

ccgtgtgtct gtttgttact tgcagctgaa gatggaaaga gccaggcgaa ggggaggcgg   1200

cggcggccgc ggccgcggag gcaagaatgt agggggctct ggcctaagca agagtagact   1260

ctatccccag gcccagcact cccactaccc ccactacgcg gcctcagcca cccctaatca   1320

ggccgggggc gcagccgaaa tccaggagct ggcctccaaa cgagtggaca tccagaaaaa   1380

gaggttttac ctagacgtga agcaaagctc ccggggccgc ttcctaaaga tagccgaagt   1440

ctggataggg agaggccggc aggacaacat cagaaagagt aaactgaccc tctccctgtc   1500

tgtggcagcg gagctgaagg actgtctagg ggacttcatc gagcactatg cccacctggg   1560

cctgaaaggc caccggcaag agcatggcca cagcaaagag caaggctcca gaaggaggca   1620

gaagcactcg gcaccctccc caccagtctc ggtggggtcc gaagagcatc ctcacagtgt   1680

cctgaaaaca gactatatcg agagggacaa taggaaatat tacctagacc taaaggaaaa   1740

tcagcggggt cgcttcctac ggattagaca aaccatgatg cgggggactg gcatgatagg   1800

ttattttggc cacagtttgg gccaagaaca gactattgtc ctcccagcac aaggaatgat   1860

tgagtttcgt gatgccttgg ttcagctgat tgaagactat ggcgaaggag acatagaaga   1920

acgaagaggt ggagacgatg acccgcttga actcccagag gggacttctt tcagagtgga   1980

caataaaagg ttctactttg atgtgggctc taataaatat ggaattttcc tgaagctcac   2040

aaattacccc aaatccagag agaatatcaa cctttttcac tgttgtcaaa tcaagcataa   2100

ggaacagccc catgatacta caaaaacagt tgaggaataa ggaataaatc tcttatgtta   2160

cacctcagaa taaaggcatt cggtgaaaga aatgaactga agttcatcat gaatgtaagg   2220

cctcagtact tgacattcct ccacggaagg gaagacaagt atcaacacca ctggcatcat   2280

ttccaaactg atcttatgtt gaataatttc caccacattg aagtaccttt cgactctatc   2340

cagtttttgg gttttgtttt ttttaattca tcaagccttt cgttttcaaa ccaccatttg   2400

tcagccttga ggtagagaga catatagatt tgaaaatact ttcttaagag atcatgtaac   2460

tatataactc tgaatttaaa aattgagggg ggagggataa tttcaaccca ctgcctctta   2520

ccagaaacat ttttttaaat ctgtaactgc tttagtgtta acagggtgca aggtggtttt   2580

tgtcccgtat tgttcttaaa aggttctcat ttattgtgat tgtattgtac tgtatgagaa   2640

caaatcataa attgccttgt attgtttata atagaccata ccacgtacta cttcagtttt   2700

tatgttccaa gtttttcagt gatgcatgtt aacagttagg tcctaaaatt ctgtggtgct   2760

aattctccca tacccaatgg tgcttttgtg gatgctaact gcacacatgc tgaacaaagc   2820

ttgaagttta aaactttcct cccttcctct gtttatatga agtaaaatga aataacttga   2880

atttgtctca aagtatcact gacaatctaa taaacttgtt tatatgtgtg atta         2934


<210>  5489
<211>  322
<212>  PRT
<213>  Homo sapiens

<400>  5489

Met Glu Arg Ala Arg Arg Arg Gly Gly Gly Gly Gly Arg Gly Arg Gly 
1               5                   10                  15


Gly Lys Asn Val Gly Gly Ser Gly Leu Ser Lys Ser Arg Leu Tyr Pro 
            20                  25                  30


Gln Ala Gln His Ser His Tyr Pro His Tyr Ala Ala Ser Ala Thr Pro 
        35                  40                  45


Asn Gln Ala Gly Gly Ala Ala Glu Ile Gln Glu Leu Ala Ser Lys Arg 
    50                  55                  60


Val Asp Ile Gln Lys Lys Arg Phe Tyr Leu Asp Val Lys Gln Ser Ser 
65                  70                  75                  80


Arg Gly Arg Phe Leu Lys Ile Ala Glu Val Trp Ile Gly Arg Gly Arg 
                85                  90                  95


Gln Asp Asn Ile Arg Lys Ser Lys Leu Thr Leu Ser Leu Ser Val Ala 
            100                 105                 110


Ala Glu Leu Lys Asp Cys Leu Gly Asp Phe Ile Glu His Tyr Ala His 
        115                 120                 125


Leu Gly Leu Lys Gly His Arg Gln Glu His Gly His Ser Lys Glu Gln 
    130                 135                 140


Gly Ser Arg Arg Arg Gln Lys His Ser Ala Pro Ser Pro Pro Val Ser 
145                 150                 155                 160


Val Gly Ser Glu Glu His Pro His Ser Val Leu Lys Thr Asp Tyr Ile 
                165                 170                 175


Glu Arg Asp Asn Arg Lys Tyr Tyr Leu Asp Leu Lys Glu Asn Gln Arg 
            180                 185                 190


Gly Arg Phe Leu Arg Ile Arg Gln Thr Met Met Arg Gly Thr Gly Met 
        195                 200                 205


Ile Gly Tyr Phe Gly His Ser Leu Gly Gln Glu Gln Thr Ile Val Leu 
    210                 215                 220


Pro Ala Gln Gly Met Ile Glu Phe Arg Asp Ala Leu Val Gln Leu Ile 
225                 230                 235                 240


Glu Asp Tyr Gly Glu Gly Asp Ile Glu Glu Arg Arg Gly Gly Asp Asp 
                245                 250                 255


Asp Pro Leu Glu Leu Pro Glu Gly Thr Ser Phe Arg Val Asp Asn Lys 
            260                 265                 270


Arg Phe Tyr Phe Asp Val Gly Ser Asn Lys Tyr Gly Ile Phe Leu Lys 
        275                 280                 285


Leu Thr Asn Tyr Pro Lys Ser Arg Glu Asn Ile Asn Leu Phe His Cys 
    290                 295                 300


Cys Gln Ile Lys His Lys Glu Gln Pro His Asp Thr Thr Lys Thr Val 
305                 310                 315                 320


Glu Glu 



<210>  5490
<211>  527
<212>  DNA
<213>  Homo sapiens

<400>  5490
ttaatgacta ttaaatatta ggacttaaaa gaccttggaa ttaatttaat cccttagttt     60

tccattttgt gacatacatc atgtagctca aattgttcat agttactaga atacgctaag    120

taaacagaat ttaaaggcta gagcttaaat tgctgattat ctcaagatat ataaatggtg    180

agaaatatac taatttcttc taaaagcata tcgcattttt accatcttcc tgtatcctct    240

ctgtacgtat agaatggagg aactatatac tgtactgtgt ttatagtacc tttttttgtc    300

ttcaaactct gcctcccagg ttcaagcgat tctccagcct cagcctcccg agtagctgga    360

attacaggcg cgtgccacca cgcccagcta atttttgtat tcttggtaga aacagggttt    420

tgccatgtgt tcgagaccag cctggctaac atagtgaaac cccatctcta ctaaaaatac    480

aaaaaattag ccaggcatgg ggatgacaga gtgagactcc atctcac                  527


<210>  5491
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  5491

Lys His Ile Ala Phe Leu Pro Ser Ser Cys Ile Leu Ser Val Arg Ile 
1               5                   10                  15


Glu Trp Arg Asn Tyr Ile Leu Tyr Cys Val Tyr Ser Thr Phe Phe Cys 
            20                  25                  30


Leu Gln Thr Leu Pro Pro Arg Phe Lys Arg Phe Ser Ser Leu Ser Leu 
        35                  40                  45


Pro Ser Ser Trp Asn Tyr Arg Arg Val Pro Pro Arg Pro Ala Asn Phe 
    50                  55                  60


Cys Ile Leu Gly Arg Asn Arg Val Leu Pro Cys Val Arg Asp Gln Pro 
65                  70                  75                  80


Gly 



<210>  5492
<211>  2874
<212>  DNA
<213>  Homo sapiens

<400>  5492
ctttctcgcg gcgctgcaac cctcccacca cagcccatcc agccccgccc agcgcgccgc     60

ggtgcgcatg cgtggaggcc ctcgctgccg ctgagcacct cgggaagtgt agtctcttcg    120

caggtgcggc tgggcagcta gagtcctgca tcccggtgga atccggagaa gtgagaacat    180

tcccgccgcc cggtcctcat tcccatcttc ccacctgtcc agtcccctcg cactcccgct    240

gcaccccacg cgccgggctt cagtcagaga gtgcactgag gaagagcgga gaccccctct    300

tcccctcagc aggctgtgcc gggggaggcg gggtccaccg cccgcccccc gccgtcgctc    360

tccccgcctc cccttccctc ccctcctggc gggtgcgggg ccggtgtccg aagtcaggcg    420

gcggcccccg cagcggccgc aggaggggcg gctgcggtgg gcgccgcggg cgatgcccct    480

gcccggctgc tccggcgggg ggcagtgcga gcggcggcgg cgggggagga ggcggggggc    540

ggcggctgcg gcggctgcag cagaggggcc gagagctggc ggtggcggcg gcggtggtcg    600

tgaagggcat cggcggcggc ggtgatggca gagatgatgt gagtgcccgc cggctggaga    660

cctggggccg cggagcgcgg gacgggcggc ggcggcgtgc gggagcggcc ccgggggcgg    720

cggagggatg cggggagcgc gggcagagcc ggagcggcgg ccgccaaccg gccggcagtg    780

gctggagccc cgcgctgcgg cgccggggga gccgggcccg gcgtgggggt cgcgggcggc    840

ggcggggcgg tcaggccgag gggcgtctgc gattgttctc aacacccctc ccccacccca    900

tcccgtgtgt ctgtttgtta cttgcagctg aagatggaaa gagccaggcg aaggggaggc    960

ggcggcggcc gcggccgcgg aggcaagaat gtagggggct ctggcctaag caagagtaga   1020

ctctatcccc aggcccagca ctcccactac ccccactacg cggcctcagc cacccctaat   1080

caggccgggg gcgcagccga aatccaggag ctggcctcca aacgagtgga catccagaaa   1140

aagaggtttt acctagacgt gaagcaaagc tcccggggcc gcttcctaaa gatagccgaa   1200

gtctggatag ggagaggccg gcaggacaac atcagaaaga gtaaactgac cctctccctg   1260

tctgtggcag cggagctgaa ggactgtcta ggggacttca tcgagcacta tgcccacctg   1320

ggcctgaaag gccaccggca agagcatggc cacagcaaag agcaaggctc cagaaggagg   1380

cagaagcact cggcaccctc cccaccagtc tcggtggggt ccgaagagca tcctcacagt   1440

gtcctgaaaa cagactatat cgagagggac aataggaaat attacctaga cctaaaggaa   1500

aatcagcggg gtcgcttcct acggattaga caaaccatga tgcgggggac tggcatgata   1560

ggttattttg gccacagttt gggccaagaa cagactattg tcctcccagc acaaggaatg   1620

attgagtttc gtgatgcctt ggttcagctg attgaagact atggcgaagg agacatagaa   1680

gaacgaagag gtggagacga tgacccgctt gaactcccag aggggacttc tttcagagtg   1740

gacaataaaa ggttctactt tgatgtgggc tctaataaat atggaatttt cctgaaggta   1800

agtgaggtga gaccacctta ccgtaatact attactgttc cattcaaagc ttggacaagg   1860

tttggggaga attttatcaa gtatgaagaa gagatgagga aaatttgcaa cagccataaa   1920

gaaaagagaa tggatggcag aaaggccagt ggtgaagaac aagaatgcct cgactagagt   1980

gaaattgaac tccatcaggc aaaatttaaa atcacaaatt ggctaaaagt actgatccat   2040

tatcctttga agaagttttt cctctttttt ggcccgttgt tattagtaat acctctagta   2100

gttgatactt caggaagtct gattctcatg ttatgttaca catagatcac tataattctt   2160

acgggaattc caaccttccc agagctaaat agtttagctg cttcaactgc tccagactat   2220

tgaagtatgc aaatcagcac aaaatgtgac attctgacat tctaaatacc ataactaaga   2280

tttacattgc actatgacat aatcccgaaa aaagatacat atacttaaat agaagtgtga   2340

ctttccccca aaagtatttc aattctactt cattaaaagc tgctaagctt acctgtaggg   2400

cagttaccac agaaacagaa attgacctcc ggtatatata aatatttact tataaaagta   2460

caagtagacg tatattgtcc gttgaataac tgaatatacc atcaaaggat caaatcttat   2520

tacctaatta aaccttaaaa atataatgtc ataatatttc ttaagaatac tatagtattc   2580

tataatttca aactttgtgg taaccctaca ttttatagtt gccatatcaa agccatggga   2640

gagttttaat tcgttattct aagtttagtt acaatccctt ctttacctct acttaatgtt   2700

ccatatattt ttattgactt tccaaagttt caggaattac ttttatgtca cattgagtgg   2760

gaggcttcat ccaatggctt tgctatggaa atcttggtgg tgtagctttt catgctaatt   2820

taaagattgc aagaggtttc ttccccaaaa tatatcatgg actcaaggtg ttat         2874


<210>  5493
<211>  347
<212>  PRT
<213>  Homo sapiens

<400>  5493

Met Glu Arg Ala Arg Arg Arg Gly Gly Gly Gly Gly Arg Gly Arg Gly 
1               5                   10                  15


Gly Lys Asn Val Gly Gly Ser Gly Leu Ser Lys Ser Arg Leu Tyr Pro 
            20                  25                  30


Gln Ala Gln His Ser His Tyr Pro His Tyr Ala Ala Ser Ala Thr Pro 
        35                  40                  45


Asn Gln Ala Gly Gly Ala Ala Glu Ile Gln Glu Leu Ala Ser Lys Arg 
    50                  55                  60


Val Asp Ile Gln Lys Lys Arg Phe Tyr Leu Asp Val Lys Gln Ser Ser 
65                  70                  75                  80


Arg Gly Arg Phe Leu Lys Ile Ala Glu Val Trp Ile Gly Arg Gly Arg 
                85                  90                  95


Gln Asp Asn Ile Arg Lys Ser Lys Leu Thr Leu Ser Leu Ser Val Ala 
            100                 105                 110


Ala Glu Leu Lys Asp Cys Leu Gly Asp Phe Ile Glu His Tyr Ala His 
        115                 120                 125


Leu Gly Leu Lys Gly His Arg Gln Glu His Gly His Ser Lys Glu Gln 
    130                 135                 140


Gly Ser Arg Arg Arg Gln Lys His Ser Ala Pro Ser Pro Pro Val Ser 
145                 150                 155                 160


Val Gly Ser Glu Glu His Pro His Ser Val Leu Lys Thr Asp Tyr Ile 
                165                 170                 175


Glu Arg Asp Asn Arg Lys Tyr Tyr Leu Asp Leu Lys Glu Asn Gln Arg 
            180                 185                 190


Gly Arg Phe Leu Arg Ile Arg Gln Thr Met Met Arg Gly Thr Gly Met 
        195                 200                 205


Ile Gly Tyr Phe Gly His Ser Leu Gly Gln Glu Gln Thr Ile Val Leu 
    210                 215                 220


Pro Ala Gln Gly Met Ile Glu Phe Arg Asp Ala Leu Val Gln Leu Ile 
225                 230                 235                 240


Glu Asp Tyr Gly Glu Gly Asp Ile Glu Glu Arg Arg Gly Gly Asp Asp 
                245                 250                 255


Asp Pro Leu Glu Leu Pro Glu Gly Thr Ser Phe Arg Val Asp Asn Lys 
            260                 265                 270


Arg Phe Tyr Phe Asp Val Gly Ser Asn Lys Tyr Gly Ile Phe Leu Lys 
        275                 280                 285


Val Ser Glu Val Arg Pro Pro Tyr Arg Asn Thr Ile Thr Val Pro Phe 
    290                 295                 300


Lys Ala Trp Thr Arg Phe Gly Glu Asn Phe Ile Lys Tyr Glu Glu Glu 
305                 310                 315                 320


Met Arg Lys Ile Cys Asn Ser His Lys Glu Lys Arg Met Asp Gly Arg 
                325                 330                 335


Lys Ala Ser Gly Glu Glu Gln Glu Cys Leu Asp 
            340                 345


<210>  5494
<211>  1396
<212>  DNA
<213>  Homo sapiens

<400>  5494
gcggcggcgg tgatggcaga gatgatgcaa gaatgtaggg ggctctggcc taagcaagag     60

tagactctat ccccaggccc agcactccca ctacccccac tacgcggcct cagccacccc    120

taatcaggcc gggggcgcag ccgaaatcca ggagctggcc tccaaacgag tggacatcca    180

gaaaaagagg ttttacctag acgtgaagca aagctcccgg ggccgcttcc taaagatagc    240

cgaagtctgg atagggagag gccggcagga caacatcaga aagagtaaac tgaccctctc    300

cctgtctgtg gcagcggagc tgaaggactg tctaggggac ttcatcgagc actatgccca    360

cctgggcctg aaaggccacc ggcaagagca tggccacagc aaagagcaag gctccagaag    420

gaggcagaag cactcggcac cctccccacc agtctcggtg gggtccgaag agcatcctca    480

cagtgtcctg aaaacagact atatcgagag ggacaatagg aaatattacc tagacctaaa    540

ggaaaatcag cggggtcgct tcctacggat tagacaaacc atgatgcggg ggactggcat    600

gataggttat tttggccaca gtttgggcca agaacagact attgtcctcc cagcacaagg    660

aatgattgag tttcgtgatg ccttggttca gctgattgaa gactatggcg aaggagacat    720

agaagaacga agaggtggag acgatgaccc gcttgaactc ccagagggga cttctttcag    780

agtggacaat aaaaggttct actttgatgt gggctctaat aaatatggaa ttttcctgaa    840

ggtaagtgag gtgagaccac cttaccgtaa tactattact gttccattca aagcttggac    900

aaggtttggg gagaatttta tcaagtatga agaagagatg aggaaaattt gcaacagcca    960

taaagaaaag agaatggatg gcagaaaggc cagtggtgaa gaacaagaat gcctcgacta   1020

gagtgaaatt gaactccatc aggcaaaatt taaaatcaca aattggctaa aagtactgat   1080

ccattatcct ttgaagaagt ttttcctctt ttttggcccg ttgttattag taatacctct   1140

agtagttgat acttcaggaa gtctgattct catgttatgt tacacataga tcactataat   1200

tcttacggga attccaacct tcccagagct aaatagttta gctgcttcaa ctgctccaga   1260

ctattgaagt atgcaaatca gcacaaaatg tgacattctg acattctaaa taccataact   1320

aagatttaca ttgcactatg acataatccc gaaaaaagat acatatactt aaatagaagt   1380

gtgactttcc cccaaa                                                   1396


<210>  5495
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  5495

Met Met Arg Gly Thr Gly Met Ile Gly Tyr Phe Gly His Ser Leu Gly 
1               5                   10                  15


Gln Glu Gln Thr Ile Val Leu Pro Ala Gln Gly Met Ile Glu Phe Arg 
            20                  25                  30


Asp Ala Leu Val Gln Leu Ile Glu Asp Tyr Gly Glu Gly Asp Ile Glu 
        35                  40                  45


Glu Arg Arg Gly Gly Asp Asp Asp Pro Leu Glu Leu Pro Glu Gly Thr 
    50                  55                  60


Ser Phe Arg Val Asp Asn Lys Arg Phe Tyr Phe Asp Val Gly Ser Asn 
65                  70                  75                  80


Lys Tyr Gly Ile Phe Leu Lys Val Ser Glu Val Arg Pro Pro Tyr Arg 
                85                  90                  95


Asn Thr Ile Thr Val Pro Phe Lys Ala Trp Thr Arg Phe Gly Glu Asn 
            100                 105                 110


Phe Ile Lys Tyr Glu Glu Glu Met Arg Lys Ile Cys Asn Ser His Lys 
        115                 120                 125


Glu Lys Arg Met Asp Gly Arg Lys Ala Ser Gly Glu Glu Gln Glu Cys 
    130                 135                 140


Leu Asp 
145


<210>  5496
<211>  614
<212>  DNA
<213>  Homo sapiens

<400>  5496
gggggaggag gcggggggcg gcggctgcgg cggctgcagc agaggggccg agagctggcg     60

gtggcggcgg cggtggtcgt gaagggcatc ggcggcggcg gtgatggcag agatgatctg    120

aagatggaaa gagccaggcg aaggggaggc ggcggcggcc gcggccgcgg aggcaagaat    180

gtagggggct ctggcctaag caagagtaga ctctatcccc aggcccagca ctcccactac    240

ccccactacg cggcctcagc cacccctaat caggccgggg gcgcagccga aatccaggag    300

ctggcctcca aacgagtgga catccagaaa aagaggtttt acctagacgt gaagcaaagc    360

tcccggggcc gcttcctaaa gatagccgaa gtctggatag ggagaggccg gcaggacaac    420

atcagaaaga gtaaactgac cctctccctg tctgtggcag cggagctgaa ggactgtcta    480

ggggacttca tcgagcacta tgcccacctg ggcctgaaag gccaccggca agagcatggc    540

cacagcaaag agcaaggctc cagaaggagg cagaagcact cggcaccctc cccaccagtc    600

tcggtggggt ccga                                                      614


<210>  5497
<211>  162
<212>  PRT
<213>  Homo sapiens

<400>  5497

Met Glu Arg Ala Arg Arg Arg Gly Gly Gly Gly Gly Arg Gly Arg Gly 
1               5                   10                  15


Gly Lys Asn Val Gly Gly Ser Gly Leu Ser Lys Ser Arg Leu Tyr Pro 
            20                  25                  30


Gln Ala Gln His Ser His Tyr Pro His Tyr Ala Ala Ser Ala Thr Pro 
        35                  40                  45


Asn Gln Ala Gly Gly Ala Ala Glu Ile Gln Glu Leu Ala Ser Lys Arg 
    50                  55                  60


Val Asp Ile Gln Lys Lys Arg Phe Tyr Leu Asp Val Lys Gln Ser Ser 
65                  70                  75                  80


Arg Gly Arg Phe Leu Lys Ile Ala Glu Val Trp Ile Gly Arg Gly Arg 
                85                  90                  95


Gln Asp Asn Ile Arg Lys Ser Lys Leu Thr Leu Ser Leu Ser Val Ala 
            100                 105                 110


Ala Glu Leu Lys Asp Cys Leu Gly Asp Phe Ile Glu His Tyr Ala His 
        115                 120                 125


Leu Gly Leu Lys Gly His Arg Gln Glu His Gly His Ser Lys Glu Gln 
    130                 135                 140


Gly Ser Arg Arg Arg Gln Lys His Ser Ala Pro Ser Pro Pro Val Ser 
145                 150                 155                 160


Val Gly 



<210>  5498
<211>  5745
<212>  DNA
<213>  Homo sapiens

<400>  5498
cagccgcccc tcctgcggcc gctgcggggg ccgccgcctg acttcggaca ccggccccgc     60

acccgccagg aggggaggga aggggaggcg gggagagcga cggcgggggg cgggcggtgg    120

accccgcctc ccccggcaca gcctgctgag gggaagaggg ggtctccgct cttcctcagt    180

gcactctctg actgaagccc ggcgcgtggg gtgcagcggg agtgcgaggg gactggacag    240

gtgggaagat gggaatgagg accgggcggc gggaatgttc tcacttctcc ggattccacc    300

gggatgcagg actctagctg cccagccgca cctgcgaaga gactacactt cccgaggtgc    360

tcagcggcag cgagggcctc cacgcatgcg caccgcggcg cgctgggcgg ggctggatgg    420

gctgtggtgg gagggttgca gcgccgcgag aaaggcgagc cgggccgggg gcggggaaag    480

gggtggggca ggaacggggg cggggacggc gctggagggg cgggtcgggt aggtctcccg    540

gagctgatgt gtactgtgtg cgccggggag gcgccggctt gtactcggca gcgcgggaat    600

aaagtttgct gatttggtgt ctagcctgga tgcctgggtt gcaggccctg cttgtggtgg    660

cgctccacag tcatccggct gaagaagacc tgttggactg gatcttctcg ggttttcttt    720

cagatattgt tttgtattta cccatgaaga cattgttttt tggactctgc aaataggaca    780

tttcaaagat gagtgaaaaa aaattggaaa caactgcaca gcagcggaaa tgtcctgaat    840

ggatgaatgt gcagaataaa agatgtgctg tagaagaaag aaaggcatgt gttcggaaga    900

gtgtttttga agatgacctc cccttcttag aattcactgg atccattgtg tatagttacg    960

atgctagtga ttgctctttc ctgtcagaag atattagcat gagtctatca gatggggatg   1020

tggtgggatt tgacatggag tggccaccat tatacaatag agggaaactt ggcaaagttg   1080

cactaattca gttgtgtgtt tctgagagca aatgttactt gttccacgtt tcttccatgt   1140

cagtttttcc ccagggatta aaaatgttgc ttgaaaataa agcagttaaa aaggcaggtg   1200

taggaattga aggagatcag tggaaacttc tacgtgactt tgatatcaaa ttgaagaatt   1260

ttgtggagtt gacagatgtt gccaataaaa agctgaaatg cacagagacc tggagcctta   1320

acagtctggt taaacacctc ttaggtaaac agctcctgaa agacaagtct atccgctgta   1380

gcaattggag taaatttcct ctcactgagg accagaaact gtatgcagcc actgatgctt   1440

atgctggttt tattatttac cgaaatttag agattttgga tgatactgtg caaaggtttg   1500

ctataaataa agaggaagaa atcctactta gcgacatgaa caaacagttg acttcaatct   1560

ctgaggaagt gatggatctg gctaagcatc ttcctcatgc tttcagtaaa ttggaaaacc   1620

cacggagggt ttctatctta ctaaaggata tttcagaaaa tctatattca ctgaggagga   1680

tgataattgg gtctactaac attgagactg aactgaggcc cagcaataat ttaaacttat   1740

tatcctttga agattcaact actgggggag tacaacagaa acaaattaga gaacatgaag   1800

ttttaattca cgttgaagat gaaacatggg acccaacact tgatcattta gctaaacatg   1860

atggagaaga tgtacttgga aataaagtgg aacgaaaaga agatggattt gaagatggag   1920

tagaagacaa caaattgaaa gagaatatgg aaagagcttg tttgatgtcg ttagatatta   1980

cagaacatga actccaaatt ttggaacagc agtctcagga agaatatctt agtgatattg   2040

cttataaatc tactgagcat ttatctccca atgataatga aaacgatacg tcctatgtaa   2100

ttgagagtga tgaagattta gaaatggaga tgcttaagca tttatctccc aatgataatg   2160

aaaacgatac gtcctatgta attgagagtg atgaagattt agaaatggag atgcttaagt   2220

ctttagaaaa cctcaatagt ggcacggtag aaccaactca ttctaaatgc ttaaaaatgg   2280

aaagaaatct gggtcttcct actaaagaag aagaagaaga tgatgaaaat gaagctaatg   2340

aaggggaaga agatgatgat aaggactttt tgtggccagc acccaatgaa gagcaagtta   2400

cttgcctcaa gatgtacttt ggccattcca gttttaaacc agttcagtgg aaagtgattc   2460

attcagtatt agaagaaaga agagataatg ttgctgtcat ggcaactgga tatggaaaga   2520

gtttgtgctt ccagtatcca cctgtttatg taggcaagat tggccttgtt atctctcccc   2580

ttatttctct gatggaagac caagtgctac agcttaaaat gtccaacatc ccagcttgct   2640

tccttggatc agcacagtca gaaaatgttc taacagatat taaattaggt aaataccgga   2700

ttgtatacgt aactccagaa tactgttcag gtaacatggg cctgctccag caacttgagg   2760

ctgatattgg tatcacgctc attgctgtgg atgaggctca ctgtatttct gagtgggggc   2820

atgattttag ggattcattc aggaagttgg gctccctaaa gacagcactg ccaatggttc   2880

caatcgttgc acttactgct actgcaagtt cttcaatccg ggaagacatt gtacgttgct   2940

taaatctgag aaatcctcag atcacctgta ctggttttga tcgaccaaac ctgtatttag   3000

aagttaggcg aaaaacaggg aatatccttc aggatctgca gccatttctt gtcaaaacaa   3060

gttcccactg ggaatttgaa ggtccaacaa tcatctactg tccttctaga aaaatgacac   3120

aacaagttac aggtgaactt aggaaactga atctatcctg tggaacatac catgcgggca   3180

tgagttttag cacaaggaaa gacattcatc ataggtttgt aagagatgaa attcagtgtg   3240

tcatagctac catagctttt ggaatgggca ttaataaagc tgacattcgc caagtcattc   3300

attacggtgc tcctaaggac atggaatcat attatcagga gattggtaga gctggtcgtg   3360

atggacttca aagttcttgt cacgtcctct gggctcctgc agacattaac ttaaataggc   3420

accttcttac tgagatacgt aatgagaagt ttcgattata caaattaaag atgatggcaa   3480

agatggaaaa atatcttcat tctagcagat gtaggagaca aatcatcttg tctcattttg   3540

aggacaaaca agtacaaaaa gcctccttgg gaattatggg aactgaaaaa tgctgtgata   3600

attgcaggtc cagattggat cattgctatt ccatggatga ctcagaggat acatcctggg   3660

actttggtcc acaagcattt aagcttttgt ctgctgtgga catcttaggc gaaaaatttg   3720

gaattgggct tccaatttta tttctccgag gatctaattc tcagcgtctt gccgatcaat   3780

atcgcaggca cagtttattt ggcactggca aggatcaaac agagagttgg tggaaggctt   3840

tttcccgtca gctgatcact gagggattct tggtagaagt ttctcggtat aacaaattta   3900

tgaagatttg cgcccttacg aaaaagggta gaaattggct tcataaagct aatacagaat   3960

ctcagagcct catccttcaa gctaatgaag aattgtgtcc aaagaagttg cttctgccta   4020

gttcgaaaac tgtatcttcg ggcaccaaag agcattgtta taatcaagta ccagttgaat   4080

taagtacaga gaagaagtct aacttggaga agttatattc ttataaacca tgtgataaga   4140

tttcttctgg gagtaacatt tctaaaaaaa gtatcatggt acagtcacca gaaaaagctt   4200

acagttcctc acagcctgtt atttcggcac aagagcagga gactcagatt gtgttatatg   4260

gcaaattggt agaagctagg cagaaacatg ccaataaaat ggatgttccc ccagctattc   4320

tggcaacaaa caagatactg gtggatatgg ccaaaatgag accaactacg gttgaaaacg   4380

taaaaaggat tgatggtgtt tctgaaggca aagctgccat gttggcccct ctgttggaag   4440

tcatcaaaca tttctgccaa acaaatagtg ttcagacaga cctcttttca agtacaaaac   4500

ctcaagaaga acagaagacg agtctggtag caaaaaataa aatatgcaca ctttcacagt   4560

ctatggccat cacatactct ttattccaag aaaagaagat gcctttgaag agcatagctg   4620

agagcaggat tctgcctctc atgacaattg gcatgcactt atcccaagcg gtgaaagctg   4680

gctgccccct tgatttggag cgagcaggcc tgactccaga ggttcagaag attattgctg   4740

atgttatccg aaaccctccc gtcaactcag atatgagtaa aattagccta atcagaatgt   4800

tagttcctga aaacattgac acgtacctta tccacatggc aattgagatc cttaaacatg   4860

gtcctgacag cggacttcaa ccttcatgtg atgtcaacaa aaggagatgt tttcccggtt   4920

ctgaagagat ctgttcaagt tctaagagaa gcaaggaaga agtaggcatc aatactgaga   4980

cttcatctgc agagagaaag agacgattac ctgtgtggtt tgccaaagga agtgatacca   5040

gcaagaaatt aatggacaaa acgaaaaggg gaggtctttt tagttaagct ggcaattacc   5100

agaacaatta tgtttcttgc tgtattataa gaggatagct atattttatt tctgaagagt   5160

aaggagtagt attttggctt aaaaatcatt ctaattacaa agttcactgt ttattgaaga   5220

actggcatct taaatcagcc ttccgcaatt catgtagttt ctgggtcttc tgggagccta   5280

cgtgagtaca tcacctaaca gaatattaaa ttagacttcc tgtaagattg ctttaagaaa   5340

ctgttactgt cctgttttct aatctcttta ttaaaacagt gtatttggaa aatgttatgt   5400

gctctgattt gatatagata acagattagt agttacatgg taattatgtg atataaaata   5460

ttcatatatt atcaaaattc tgttttgtaa atgtaagaaa gcatagttat tttacaaatt   5520

gtttttactg tcttttgaag aagttcttaa atacgttgtt aaatggtatt agttgaccag   5580

ggcagtgaaa atgaaaccgc attttgggtg ccattaaata gggaaaaaac atgtaaaaaa   5640

tgtaaaatgg agaccaattg cactaggcaa gtgtatattt tgtattttat atacaatttc   5700

tattattttt caagtaataa aacaatgttt ttcatactga atatt                   5745


<210>  5499
<211>  1432
<212>  PRT
<213>  Homo sapiens

<400>  5499

Met Ser Glu Lys Lys Leu Glu Thr Thr Ala Gln Gln Arg Lys Cys Pro 
1               5                   10                  15


Glu Trp Met Asn Val Gln Asn Lys Arg Cys Ala Val Glu Glu Arg Lys 
            20                  25                  30


Ala Cys Val Arg Lys Ser Val Phe Glu Asp Asp Leu Pro Phe Leu Glu 
        35                  40                  45


Phe Thr Gly Ser Ile Val Tyr Ser Tyr Asp Ala Ser Asp Cys Ser Phe 
    50                  55                  60


Leu Ser Glu Asp Ile Ser Met Ser Leu Ser Asp Gly Asp Val Val Gly 
65                  70                  75                  80


Phe Asp Met Glu Trp Pro Pro Leu Tyr Asn Arg Gly Lys Leu Gly Lys 
                85                  90                  95


Val Ala Leu Ile Gln Leu Cys Val Ser Glu Ser Lys Cys Tyr Leu Phe 
            100                 105                 110


His Val Ser Ser Met Ser Val Phe Pro Gln Gly Leu Lys Met Leu Leu 
        115                 120                 125


Glu Asn Lys Ala Val Lys Lys Ala Gly Val Gly Ile Glu Gly Asp Gln 
    130                 135                 140


Trp Lys Leu Leu Arg Asp Phe Asp Ile Lys Leu Lys Asn Phe Val Glu 
145                 150                 155                 160


Leu Thr Asp Val Ala Asn Lys Lys Leu Lys Cys Thr Glu Thr Trp Ser 
                165                 170                 175


Leu Asn Ser Leu Val Lys His Leu Leu Gly Lys Gln Leu Leu Lys Asp 
            180                 185                 190


Lys Ser Ile Arg Cys Ser Asn Trp Ser Lys Phe Pro Leu Thr Glu Asp 
        195                 200                 205


Gln Lys Leu Tyr Ala Ala Thr Asp Ala Tyr Ala Gly Phe Ile Ile Tyr 
    210                 215                 220


Arg Asn Leu Glu Ile Leu Asp Asp Thr Val Gln Arg Phe Ala Ile Asn 
225                 230                 235                 240


Lys Glu Glu Glu Ile Leu Leu Ser Asp Met Asn Lys Gln Leu Thr Ser 
                245                 250                 255


Ile Ser Glu Glu Val Met Asp Leu Ala Lys His Leu Pro His Ala Phe 
            260                 265                 270


Ser Lys Leu Glu Asn Pro Arg Arg Val Ser Ile Leu Leu Lys Asp Ile 
        275                 280                 285


Ser Glu Asn Leu Tyr Ser Leu Arg Arg Met Ile Ile Gly Ser Thr Asn 
    290                 295                 300


Ile Glu Thr Glu Leu Arg Pro Ser Asn Asn Leu Asn Leu Leu Ser Phe 
305                 310                 315                 320


Glu Asp Ser Thr Thr Gly Gly Val Gln Gln Lys Gln Ile Arg Glu His 
                325                 330                 335


Glu Val Leu Ile His Val Glu Asp Glu Thr Trp Asp Pro Thr Leu Asp 
            340                 345                 350


His Leu Ala Lys His Asp Gly Glu Asp Val Leu Gly Asn Lys Val Glu 
        355                 360                 365


Arg Lys Glu Asp Gly Phe Glu Asp Gly Val Glu Asp Asn Lys Leu Lys 
    370                 375                 380


Glu Asn Met Glu Arg Ala Cys Leu Met Ser Leu Asp Ile Thr Glu His 
385                 390                 395                 400


Glu Leu Gln Ile Leu Glu Gln Gln Ser Gln Glu Glu Tyr Leu Ser Asp 
                405                 410                 415


Ile Ala Tyr Lys Ser Thr Glu His Leu Ser Pro Asn Asp Asn Glu Asn 
            420                 425                 430


Asp Thr Ser Tyr Val Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met 
        435                 440                 445


Leu Lys His Leu Ser Pro Asn Asp Asn Glu Asn Asp Thr Ser Tyr Val 
    450                 455                 460


Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met Leu Lys Ser Leu Glu 
465                 470                 475                 480


Asn Leu Asn Ser Gly Thr Val Glu Pro Thr His Ser Lys Cys Leu Lys 
                485                 490                 495


Met Glu Arg Asn Leu Gly Leu Pro Thr Lys Glu Glu Glu Glu Asp Asp 
            500                 505                 510


Glu Asn Glu Ala Asn Glu Gly Glu Glu Asp Asp Asp Lys Asp Phe Leu 
        515                 520                 525


Trp Pro Ala Pro Asn Glu Glu Gln Val Thr Cys Leu Lys Met Tyr Phe 
    530                 535                 540


Gly His Ser Ser Phe Lys Pro Val Gln Trp Lys Val Ile His Ser Val 
545                 550                 555                 560


Leu Glu Glu Arg Arg Asp Asn Val Ala Val Met Ala Thr Gly Tyr Gly 
                565                 570                 575


Lys Ser Leu Cys Phe Gln Tyr Pro Pro Val Tyr Val Gly Lys Ile Gly 
            580                 585                 590


Leu Val Ile Ser Pro Leu Ile Ser Leu Met Glu Asp Gln Val Leu Gln 
        595                 600                 605


Leu Lys Met Ser Asn Ile Pro Ala Cys Phe Leu Gly Ser Ala Gln Ser 
    610                 615                 620


Glu Asn Val Leu Thr Asp Ile Lys Leu Gly Lys Tyr Arg Ile Val Tyr 
625                 630                 635                 640


Val Thr Pro Glu Tyr Cys Ser Gly Asn Met Gly Leu Leu Gln Gln Leu 
                645                 650                 655


Glu Ala Asp Ile Gly Ile Thr Leu Ile Ala Val Asp Glu Ala His Cys 
            660                 665                 670


Ile Ser Glu Trp Gly His Asp Phe Arg Asp Ser Phe Arg Lys Leu Gly 
        675                 680                 685


Ser Leu Lys Thr Ala Leu Pro Met Val Pro Ile Val Ala Leu Thr Ala 
    690                 695                 700


Thr Ala Ser Ser Ser Ile Arg Glu Asp Ile Val Arg Cys Leu Asn Leu 
705                 710                 715                 720


Arg Asn Pro Gln Ile Thr Cys Thr Gly Phe Asp Arg Pro Asn Leu Tyr 
                725                 730                 735


Leu Glu Val Arg Arg Lys Thr Gly Asn Ile Leu Gln Asp Leu Gln Pro 
            740                 745                 750


Phe Leu Val Lys Thr Ser Ser His Trp Glu Phe Glu Gly Pro Thr Ile 
        755                 760                 765


Ile Tyr Cys Pro Ser Arg Lys Met Thr Gln Gln Val Thr Gly Glu Leu 
    770                 775                 780


Arg Lys Leu Asn Leu Ser Cys Gly Thr Tyr His Ala Gly Met Ser Phe 
785                 790                 795                 800


Ser Thr Arg Lys Asp Ile His His Arg Phe Val Arg Asp Glu Ile Gln 
                805                 810                 815


Cys Val Ile Ala Thr Ile Ala Phe Gly Met Gly Ile Asn Lys Ala Asp 
            820                 825                 830


Ile Arg Gln Val Ile His Tyr Gly Ala Pro Lys Asp Met Glu Ser Tyr 
        835                 840                 845


Tyr Gln Glu Ile Gly Arg Ala Gly Arg Asp Gly Leu Gln Ser Ser Cys 
    850                 855                 860


His Val Leu Trp Ala Pro Ala Asp Ile Asn Leu Asn Arg His Leu Leu 
865                 870                 875                 880


Thr Glu Ile Arg Asn Glu Lys Phe Arg Leu Tyr Lys Leu Lys Met Met 
                885                 890                 895


Ala Lys Met Glu Lys Tyr Leu His Ser Ser Arg Cys Arg Arg Gln Ile 
            900                 905                 910


Ile Leu Ser His Phe Glu Asp Lys Gln Val Gln Lys Ala Ser Leu Gly 
        915                 920                 925


Ile Met Gly Thr Glu Lys Cys Cys Asp Asn Cys Arg Ser Arg Leu Asp 
    930                 935                 940


His Cys Tyr Ser Met Asp Asp Ser Glu Asp Thr Ser Trp Asp Phe Gly 
945                 950                 955                 960


Pro Gln Ala Phe Lys Leu Leu Ser Ala Val Asp Ile Leu Gly Glu Lys 
                965                 970                 975


Phe Gly Ile Gly Leu Pro Ile Leu Phe Leu Arg Gly Ser Asn Ser Gln 
            980                 985                 990


Arg Leu Ala Asp Gln Tyr Arg Arg His Ser Leu Phe Gly Thr Gly Lys 
        995                 1000                1005


Asp Gln Thr Glu Ser Trp Trp Lys Ala Phe Ser Arg Gln Leu Ile Thr 
    1010                1015                1020


Glu Gly Phe Leu Val Glu Val Ser Arg Tyr Asn Lys Phe Met Lys Ile 
1025                1030                1035                1040


Cys Ala Leu Thr Lys Lys Gly Arg Asn Trp Leu His Lys Ala Asn Thr 
                1045                1050                1055


Glu Ser Gln Ser Leu Ile Leu Gln Ala Asn Glu Glu Leu Cys Pro Lys 
            1060                1065                1070


Lys Leu Leu Leu Pro Ser Ser Lys Thr Val Ser Ser Gly Thr Lys Glu 
        1075                1080                1085


His Cys Tyr Asn Gln Val Pro Val Glu Leu Ser Thr Glu Lys Lys Ser 
    1090                1095                1100


Asn Leu Glu Lys Leu Tyr Ser Tyr Lys Pro Cys Asp Lys Ile Ser Ser 
1105                1110                1115                1120


Gly Ser Asn Ile Ser Lys Lys Ser Ile Met Val Gln Ser Pro Glu Lys 
                1125                1130                1135


Ala Tyr Ser Ser Ser Gln Pro Val Ile Ser Ala Gln Glu Gln Glu Thr 
            1140                1145                1150


Gln Ile Val Leu Tyr Gly Lys Leu Val Glu Ala Arg Gln Lys His Ala 
        1155                1160                1165


Asn Lys Met Asp Val Pro Pro Ala Ile Leu Ala Thr Asn Lys Ile Leu 
    1170                1175                1180


Val Asp Met Ala Lys Met Arg Pro Thr Thr Val Glu Asn Val Lys Arg 
1185                1190                1195                1200


Ile Asp Gly Val Ser Glu Gly Lys Ala Ala Met Leu Ala Pro Leu Leu 
                1205                1210                1215


Glu Val Ile Lys His Phe Cys Gln Thr Asn Ser Val Gln Thr Asp Leu 
            1220                1225                1230


Phe Ser Ser Thr Lys Pro Gln Glu Glu Gln Lys Thr Ser Leu Val Ala 
        1235                1240                1245


Lys Asn Lys Ile Cys Thr Leu Ser Gln Ser Met Ala Ile Thr Tyr Ser 
    1250                1255                1260


Leu Phe Gln Glu Lys Lys Met Pro Leu Lys Ser Ile Ala Glu Ser Arg 
1265                1270                1275                1280


Ile Leu Pro Leu Met Thr Ile Gly Met His Leu Ser Gln Ala Val Lys 
                1285                1290                1295


Ala Gly Cys Pro Leu Asp Leu Glu Arg Ala Gly Leu Thr Pro Glu Val 
            1300                1305                1310


Gln Lys Ile Ile Ala Asp Val Ile Arg Asn Pro Pro Val Asn Ser Asp 
        1315                1320                1325


Met Ser Lys Ile Ser Leu Ile Arg Met Leu Val Pro Glu Asn Ile Asp 
    1330                1335                1340


Thr Tyr Leu Ile His Met Ala Ile Glu Ile Leu Lys His Gly Pro Asp 
1345                1350                1355                1360


Ser Gly Leu Gln Pro Ser Cys Asp Val Asn Lys Arg Arg Cys Phe Pro 
                1365                1370                1375


Gly Ser Glu Glu Ile Cys Ser Ser Ser Lys Arg Ser Lys Glu Glu Val 
            1380                1385                1390


Gly Ile Asn Thr Glu Thr Ser Ser Ala Glu Arg Lys Arg Arg Leu Pro 
        1395                1400                1405


Val Trp Phe Ala Lys Gly Ser Asp Thr Ser Lys Lys Leu Met Asp Lys 
    1410                1415                1420


Thr Lys Arg Gly Gly Leu Phe Ser 
1425                1430


<210>  5500
<211>  5119
<212>  DNA
<213>  Homo sapiens

<400>  5500
ggagctgatg tgtactgtgt gcgccgggga ggcgccggct tgtactcggc agcgcgggaa     60

taaagtttgc tgatttggtg tctagcctgg atgcctgggt tgcaggccct gcttgtggtg    120

gcgctccaca gtcatccggc tgaagaagac ctgttggact ggatcttctc gggttttctt    180

tcagatattg ttttgtattt acccatgaag acattgtttt ttggactctg caaataggac    240

atttcaaaga tgagtgaaaa aaaattggaa acaactgcac agcagcggaa atgtcctgaa    300

tggatgaatg tgcagaataa aagatgtgct gtagaagaaa gaaaggcatg tgttcggaag    360

agtgtttttg aagatgacct ccccttctta gaattcactg gatccattgt gtatagttac    420

gatgctagtg attgctcttt cctgtcagaa gatattagca tgagtctatc agatggggat    480

gtggtgggat ttgacatgga gtggccacca ttatacaata gagggaaact tggcaaagtt    540

gcactaattc agttgtgtgt ttctgagagc aaatgttact tgttccacgt ttcttccatg    600

tcagtttttc cccagggatt aaaaatgttg cttgaaaata aagcagttaa aaaggcaggt    660

gtaggaattg aaggagatca gtggaaactt ctacgtgact ttgatatcaa attgaagaat    720

tttgtggagt tgacagatgt tgccaataaa aagctgaaat gcacagagac ctggagcctt    780

aacagtctgg ttaaacacct cttaggtaaa cagctcctga aagacaagtc tatccgctgt    840

agcaattgga gtaaatttcc tctcactgag gaccagaaac tgtatgcagc cactgatgct    900

tatgctggtt ttattattta ccgaaattta gagattttgg atgatactgt gcaaaggttt    960

gctataaata aagaggaaga aatcctactt agcgacatga acaaacagtt gacttcaatc   1020

tctgaggaag tgatggatct ggctaagcat cttcctcatg ctttcagtaa attggaaaac   1080

ccacggaggg tttctatctt actaaaggat atttcagaaa atctatattc actgaggagg   1140

atgataattg ggtctactaa cattgagact gaactgaggc ccagcaataa tttaaactta   1200

ttatcctttg aagattcaac tactggggga gtacaacaga aacaaattag agaacatgaa   1260

gttttaattc acgttgaaga tgaaacatgg gacccaacac ttgatcattt agctaaacat   1320

gatggagaag atgtacttgg aaataaagtg gaacgaaaag aagatggatt tgaagatgga   1380

gtagaagaca acaaattgaa agagaatatg gaaagagctt gtttgatgtc gttagatatt   1440

acagaacatg aactccaaat tttggaacag cagtctcagg aagaatatct tagtgatatt   1500

gcttataaat ctactgagca tttatctccc aatgataatg aaaacgatac gtcctatgta   1560

attgagagtg atgaagattt agaaatggag atgcttaagc atttatctcc caatgataat   1620

gaaaacgata cgtcctatgt aattgagagt gatgaagatt tagaaatgga gatgcttaag   1680

tctttagaaa acctcaatag tggcacggta gaaccaactc attctaaatg cttaaaaatg   1740

gaaagaaatc tggcacccaa tgaagagcaa gttacttgcc tcaagatgta ctttggccat   1800

tccagtttta aaccagttca gtggaaagtg attcattcag tattagaaga aagaagagat   1860

aatgttgctg tcatggcaac tggatatgga aagagtttgt gcttccagta tccacctgtt   1920

tatgtaggca agattggcct tgttatctct ccccttattt ctctgatgga agaccaagtg   1980

ctacagctta aaatgtccaa catcccagct tgcttccttg gatcagcaca gtcagaaaat   2040

gttctaacag atattaaatt aggtaaatac cggattgtat acgtaactcc agaatactgt   2100

tcaggtaaca tgggcctgct ccagcaactt gaggctgata ttggtatcac gctcattgct   2160

gtggatgagg ctcactgtat ttctgagtgg gggcatgatt ttagggattc attcaggaag   2220

ttgggctccc taaagacagc actgccaatg gttccaatcg ttgcacttac tgctactgca   2280

agttcttcaa tccgggaaga cattgtacgt tgcttaaatc tgagaaatcc tcagatcacc   2340

tgtactggtt ttgatcgacc aaacctgtat ttagaagtta ggcgaaaaac agggaatatc   2400

cttcaggatc tgcagccatt tcttgtcaaa acaagttccc actgggaatt tgaaggtcca   2460

acaatcatct actgtccttc tagaaaaatg acacaacaag ttacaggtga acttaggaaa   2520

ctgaatctat cctgtggaac ataccatgcg ggcatgagtt ttagcacaag gaaagacatt   2580

catcataggt ttgtaagaga tgaaattcag tgtgtcatag ctaccatagc ttttggaatg   2640

ggcattaata aagctgacat tcgccaagtc attcattacg gtgctcctaa ggacatggaa   2700

tcatattatc aggagattgg tagagctggt cgtgatggac ttcaaagttc ttgtcacgtc   2760

ctctgggctc ctgcagacat taacttaaat aggcaccttc ttactgagat acgtaatgag   2820

aagtttcgat tatacaaatt aaagatgatg gcaaagatgg aaaaatatct tcattctagc   2880

agatgtagga gacaaatcat cttgtctcat tttgaggaca aacaagtaca aaaagcctcc   2940

ttgggaatta tgggaactga aaaatgctgt gataattgca ggtccagatt ggatcattgc   3000

tattccatgg atgactcaga ggatacatcc tgggactttg gtccacaagc atttaagctt   3060

ttgtctgctg tggacatctt aggcgaaaaa tttggaattg ggcttccaat tttatttctc   3120

cgaggatcta attctcagcg tcttgccgat caatatcgca ggcacagttt atttggcact   3180

ggcaaggatc aaacagagag ttggtggaag gctttttccc gtcagctgat cactgaggga   3240

ttcttggtag aagtttctcg gtataacaaa tttatgaaga tttgcgccct tacgaaaaag   3300

ggtagaaatt ggcttcataa agctaataca gaatctcaga gcctcatcct tcaagctaat   3360

gaagaattgt gtccaaagaa gttgcttctg cctagttcga aaactgtatc ttcgggcacc   3420

aaagagcatt gttataatca agtaccagtt gaattaagta cagagaagaa gtctaacttg   3480

gagaagttat attcttataa accatgtgat aagatttctt ctgggagtaa catttctaaa   3540

aaaagtatca tggtacagtc accagaaaaa gcttacagtt cctcacagcc tgttatttcg   3600

gcacaagagc aggagactca gattgtgtta tatggcaaat tggtagaagc taggcagaaa   3660

catgccaata aaatggatgt tcccccagct attctggcaa caaacaagat actggtggat   3720

atggccaaaa tgagaccaac tacggttgaa aacgtaaaaa ggattgatgg tgtttctgaa   3780

ggcaaagctg ccatgttggc ccctctgttg gaagtcatca aacatttctg ccaaacaaat   3840

agtgttcaga cagacctctt ttcaagtaca aaacctcaag aagaacagaa gacgagtctg   3900

gtagcaaaaa ataaaatatg cacactttca cagtctatgg ccatcacata ctctttattc   3960

caagaaaaga agatgccttt gaagagcata gctgagagca ggattctgcc tctcatgaca   4020

attggcatgc acttatccca agcggtgaaa gctggctgcc cccttgattt ggagcgagca   4080

ggcctgactc cagaggttca gaagattatt gctgatgtta tccgaaaccc tcccgtcaac   4140

tcagatatga gtaaaattag cctaatcaga atgttagttc ctgaaaacat tgacacgtac   4200

cttatccaca tggcaattga gatccttaaa catggtcctg acagcggact tcaaccttca   4260

tgtgatgtca acaaaaggag atgttttccc ggttctgaag agatctgttc aagttctaag   4320

agaagcaagg aagaagtagg catcaatact gagacttcat ctgcagagag aaagagacga   4380

ttacctgtgt ggtttgccaa aggaagtgat accagcaaga aattaatgga caaaacgaaa   4440

aggggaggtc tttttagtta agctggcaat taccagaaca attatgtttc ttgctgtatt   4500

ataagaggat agctatattt tatttctgaa gagtaaggag tagtattttg gcttaaaaat   4560

cattctaatt acaaagttca ctgtttattg aagaactggc atcttaaatc agccttccgc   4620

aattcatgta gtttctgggt cttctgggag cctacgtgag tacatcacct aacagaatat   4680

taaattagac ttcctgtaag attgctttaa gaaactgtta ctgtcctgtt ttctaatctc   4740

tttattaaaa cagtgtattt ggaaaatgtt atgtgctctg atttgatata gataacagat   4800

tagtagttac atggtaatta tgtgatataa aatattcata tattatcaaa attctgtttt   4860

gtaaatgtaa gaaagcatag ttattttaca aattgttttt actgtctttt gaagaagttc   4920

ttaaatacgt tgttaaatgg tattagttga ccagggcagt gaaaatgaaa ccgcattttg   4980

ggtgccatta aatagggaaa aaacatgtaa aaaatgtaaa atggagacca attgcactag   5040

gcaagtgtat attttgtatt ttatatacaa tttctattat ttttcaagta ataaaacaat   5100

gtttttcata ctgaatatt                                                5119


<210>  5501
<211>  1403
<212>  PRT
<213>  Homo sapiens

<400>  5501

Met Ser Glu Lys Lys Leu Glu Thr Thr Ala Gln Gln Arg Lys Cys Pro 
1               5                   10                  15


Glu Trp Met Asn Val Gln Asn Lys Arg Cys Ala Val Glu Glu Arg Lys 
            20                  25                  30


Ala Cys Val Arg Lys Ser Val Phe Glu Asp Asp Leu Pro Phe Leu Glu 
        35                  40                  45


Phe Thr Gly Ser Ile Val Tyr Ser Tyr Asp Ala Ser Asp Cys Ser Phe 
    50                  55                  60


Leu Ser Glu Asp Ile Ser Met Ser Leu Ser Asp Gly Asp Val Val Gly 
65                  70                  75                  80


Phe Asp Met Glu Trp Pro Pro Leu Tyr Asn Arg Gly Lys Leu Gly Lys 
                85                  90                  95


Val Ala Leu Ile Gln Leu Cys Val Ser Glu Ser Lys Cys Tyr Leu Phe 
            100                 105                 110


His Val Ser Ser Met Ser Val Phe Pro Gln Gly Leu Lys Met Leu Leu 
        115                 120                 125


Glu Asn Lys Ala Val Lys Lys Ala Gly Val Gly Ile Glu Gly Asp Gln 
    130                 135                 140


Trp Lys Leu Leu Arg Asp Phe Asp Ile Lys Leu Lys Asn Phe Val Glu 
145                 150                 155                 160


Leu Thr Asp Val Ala Asn Lys Lys Leu Lys Cys Thr Glu Thr Trp Ser 
                165                 170                 175


Leu Asn Ser Leu Val Lys His Leu Leu Gly Lys Gln Leu Leu Lys Asp 
            180                 185                 190


Lys Ser Ile Arg Cys Ser Asn Trp Ser Lys Phe Pro Leu Thr Glu Asp 
        195                 200                 205


Gln Lys Leu Tyr Ala Ala Thr Asp Ala Tyr Ala Gly Phe Ile Ile Tyr 
    210                 215                 220


Arg Asn Leu Glu Ile Leu Asp Asp Thr Val Gln Arg Phe Ala Ile Asn 
225                 230                 235                 240


Lys Glu Glu Glu Ile Leu Leu Ser Asp Met Asn Lys Gln Leu Thr Ser 
                245                 250                 255


Ile Ser Glu Glu Val Met Asp Leu Ala Lys His Leu Pro His Ala Phe 
            260                 265                 270


Ser Lys Leu Glu Asn Pro Arg Arg Val Ser Ile Leu Leu Lys Asp Ile 
        275                 280                 285


Ser Glu Asn Leu Tyr Ser Leu Arg Arg Met Ile Ile Gly Ser Thr Asn 
    290                 295                 300


Ile Glu Thr Glu Leu Arg Pro Ser Asn Asn Leu Asn Leu Leu Ser Phe 
305                 310                 315                 320


Glu Asp Ser Thr Thr Gly Gly Val Gln Gln Lys Gln Ile Arg Glu His 
                325                 330                 335


Glu Val Leu Ile His Val Glu Asp Glu Thr Trp Asp Pro Thr Leu Asp 
            340                 345                 350


His Leu Ala Lys His Asp Gly Glu Asp Val Leu Gly Asn Lys Val Glu 
        355                 360                 365


Arg Lys Glu Asp Gly Phe Glu Asp Gly Val Glu Asp Asn Lys Leu Lys 
    370                 375                 380


Glu Asn Met Glu Arg Ala Cys Leu Met Ser Leu Asp Ile Thr Glu His 
385                 390                 395                 400


Glu Leu Gln Ile Leu Glu Gln Gln Ser Gln Glu Glu Tyr Leu Ser Asp 
                405                 410                 415


Ile Ala Tyr Lys Ser Thr Glu His Leu Ser Pro Asn Asp Asn Glu Asn 
            420                 425                 430


Asp Thr Ser Tyr Val Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met 
        435                 440                 445


Leu Lys His Leu Ser Pro Asn Asp Asn Glu Asn Asp Thr Ser Tyr Val 
    450                 455                 460


Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met Leu Lys Ser Leu Glu 
465                 470                 475                 480


Asn Leu Asn Ser Gly Thr Val Glu Pro Thr His Ser Lys Cys Leu Lys 
                485                 490                 495


Met Glu Arg Asn Leu Ala Pro Asn Glu Glu Gln Val Thr Cys Leu Lys 
            500                 505                 510


Met Tyr Phe Gly His Ser Ser Phe Lys Pro Val Gln Trp Lys Val Ile 
        515                 520                 525


His Ser Val Leu Glu Glu Arg Arg Asp Asn Val Ala Val Met Ala Thr 
    530                 535                 540


Gly Tyr Gly Lys Ser Leu Cys Phe Gln Tyr Pro Pro Val Tyr Val Gly 
545                 550                 555                 560


Lys Ile Gly Leu Val Ile Ser Pro Leu Ile Ser Leu Met Glu Asp Gln 
                565                 570                 575


Val Leu Gln Leu Lys Met Ser Asn Ile Pro Ala Cys Phe Leu Gly Ser 
            580                 585                 590


Ala Gln Ser Glu Asn Val Leu Thr Asp Ile Lys Leu Gly Lys Tyr Arg 
        595                 600                 605


Ile Val Tyr Val Thr Pro Glu Tyr Cys Ser Gly Asn Met Gly Leu Leu 
    610                 615                 620


Gln Gln Leu Glu Ala Asp Ile Gly Ile Thr Leu Ile Ala Val Asp Glu 
625                 630                 635                 640


Ala His Cys Ile Ser Glu Trp Gly His Asp Phe Arg Asp Ser Phe Arg 
                645                 650                 655


Lys Leu Gly Ser Leu Lys Thr Ala Leu Pro Met Val Pro Ile Val Ala 
            660                 665                 670


Leu Thr Ala Thr Ala Ser Ser Ser Ile Arg Glu Asp Ile Val Arg Cys 
        675                 680                 685


Leu Asn Leu Arg Asn Pro Gln Ile Thr Cys Thr Gly Phe Asp Arg Pro 
    690                 695                 700


Asn Leu Tyr Leu Glu Val Arg Arg Lys Thr Gly Asn Ile Leu Gln Asp 
705                 710                 715                 720


Leu Gln Pro Phe Leu Val Lys Thr Ser Ser His Trp Glu Phe Glu Gly 
                725                 730                 735


Pro Thr Ile Ile Tyr Cys Pro Ser Arg Lys Met Thr Gln Gln Val Thr 
            740                 745                 750


Gly Glu Leu Arg Lys Leu Asn Leu Ser Cys Gly Thr Tyr His Ala Gly 
        755                 760                 765


Met Ser Phe Ser Thr Arg Lys Asp Ile His His Arg Phe Val Arg Asp 
    770                 775                 780


Glu Ile Gln Cys Val Ile Ala Thr Ile Ala Phe Gly Met Gly Ile Asn 
785                 790                 795                 800


Lys Ala Asp Ile Arg Gln Val Ile His Tyr Gly Ala Pro Lys Asp Met 
                805                 810                 815


Glu Ser Tyr Tyr Gln Glu Ile Gly Arg Ala Gly Arg Asp Gly Leu Gln 
            820                 825                 830


Ser Ser Cys His Val Leu Trp Ala Pro Ala Asp Ile Asn Leu Asn Arg 
        835                 840                 845


His Leu Leu Thr Glu Ile Arg Asn Glu Lys Phe Arg Leu Tyr Lys Leu 
    850                 855                 860


Lys Met Met Ala Lys Met Glu Lys Tyr Leu His Ser Ser Arg Cys Arg 
865                 870                 875                 880


Arg Gln Ile Ile Leu Ser His Phe Glu Asp Lys Gln Val Gln Lys Ala 
                885                 890                 895


Ser Leu Gly Ile Met Gly Thr Glu Lys Cys Cys Asp Asn Cys Arg Ser 
            900                 905                 910


Arg Leu Asp His Cys Tyr Ser Met Asp Asp Ser Glu Asp Thr Ser Trp 
        915                 920                 925


Asp Phe Gly Pro Gln Ala Phe Lys Leu Leu Ser Ala Val Asp Ile Leu 
    930                 935                 940


Gly Glu Lys Phe Gly Ile Gly Leu Pro Ile Leu Phe Leu Arg Gly Ser 
945                 950                 955                 960


Asn Ser Gln Arg Leu Ala Asp Gln Tyr Arg Arg His Ser Leu Phe Gly 
                965                 970                 975


Thr Gly Lys Asp Gln Thr Glu Ser Trp Trp Lys Ala Phe Ser Arg Gln 
            980                 985                 990


Leu Ile Thr Glu Gly Phe Leu Val Glu Val Ser Arg Tyr Asn Lys Phe 
        995                 1000                1005


Met Lys Ile Cys Ala Leu Thr Lys Lys Gly Arg Asn Trp Leu His Lys 
    1010                1015                1020


Ala Asn Thr Glu Ser Gln Ser Leu Ile Leu Gln Ala Asn Glu Glu Leu 
1025                1030                1035                1040


Cys Pro Lys Lys Leu Leu Leu Pro Ser Ser Lys Thr Val Ser Ser Gly 
                1045                1050                1055


Thr Lys Glu His Cys Tyr Asn Gln Val Pro Val Glu Leu Ser Thr Glu 
            1060                1065                1070


Lys Lys Ser Asn Leu Glu Lys Leu Tyr Ser Tyr Lys Pro Cys Asp Lys 
        1075                1080                1085


Ile Ser Ser Gly Ser Asn Ile Ser Lys Lys Ser Ile Met Val Gln Ser 
    1090                1095                1100


Pro Glu Lys Ala Tyr Ser Ser Ser Gln Pro Val Ile Ser Ala Gln Glu 
1105                1110                1115                1120


Gln Glu Thr Gln Ile Val Leu Tyr Gly Lys Leu Val Glu Ala Arg Gln 
                1125                1130                1135


Lys His Ala Asn Lys Met Asp Val Pro Pro Ala Ile Leu Ala Thr Asn 
            1140                1145                1150


Lys Ile Leu Val Asp Met Ala Lys Met Arg Pro Thr Thr Val Glu Asn 
        1155                1160                1165


Val Lys Arg Ile Asp Gly Val Ser Glu Gly Lys Ala Ala Met Leu Ala 
    1170                1175                1180


Pro Leu Leu Glu Val Ile Lys His Phe Cys Gln Thr Asn Ser Val Gln 
1185                1190                1195                1200


Thr Asp Leu Phe Ser Ser Thr Lys Pro Gln Glu Glu Gln Lys Thr Ser 
                1205                1210                1215


Leu Val Ala Lys Asn Lys Ile Cys Thr Leu Ser Gln Ser Met Ala Ile 
            1220                1225                1230


Thr Tyr Ser Leu Phe Gln Glu Lys Lys Met Pro Leu Lys Ser Ile Ala 
        1235                1240                1245


Glu Ser Arg Ile Leu Pro Leu Met Thr Ile Gly Met His Leu Ser Gln 
    1250                1255                1260


Ala Val Lys Ala Gly Cys Pro Leu Asp Leu Glu Arg Ala Gly Leu Thr 
1265                1270                1275                1280


Pro Glu Val Gln Lys Ile Ile Ala Asp Val Ile Arg Asn Pro Pro Val 
                1285                1290                1295


Asn Ser Asp Met Ser Lys Ile Ser Leu Ile Arg Met Leu Val Pro Glu 
            1300                1305                1310


Asn Ile Asp Thr Tyr Leu Ile His Met Ala Ile Glu Ile Leu Lys His 
        1315                1320                1325


Gly Pro Asp Ser Gly Leu Gln Pro Ser Cys Asp Val Asn Lys Arg Arg 
    1330                1335                1340


Cys Phe Pro Gly Ser Glu Glu Ile Cys Ser Ser Ser Lys Arg Ser Lys 
1345                1350                1355                1360


Glu Glu Val Gly Ile Asn Thr Glu Thr Ser Ser Ala Glu Arg Lys Arg 
                1365                1370                1375


Arg Leu Pro Val Trp Phe Ala Lys Gly Ser Asp Thr Ser Lys Lys Leu 
            1380                1385                1390


Met Asp Lys Thr Lys Arg Gly Gly Leu Phe Ser 
        1395                1400


<210>  5502
<211>  6163
<212>  DNA
<213>  Homo sapiens

<400>  5502
ggagctgatg tgtactgtgt gcgccgggga ggcgccggct tgtactcggc agcgcgggaa     60

taaagtttgc tgatttggtg tctagcctgg atgcctgggt tgcaggccct gcttgtggtg    120

gcgctccaca gtcatccggc tgaagaagac ctgttggact ggatcttctc gggttttctt    180

tcagatattg ttttgtattt acccatgaag acattgtttt ttggactctg caaataggac    240

atttcaaaga tgagtgaaaa aaaattggaa acaactgcac agcagcggaa atgtcctgaa    300

tggatgaatg tgcagaataa aagatgtgct gtagaagaaa gaaaggcatg tgttcggaag    360

agtgtttttg aagatgacct ccccttctta gaattcactg gatccattgt gtatagttac    420

gatgctagtg attgctcttt cctgtcagaa gatattagca tgagtctatc agatggggat    480

gtggtgggat ttgacatgga gtggccacca ttatacaata gagggaaact tggcaaagtt    540

gcactaattc agttgtgtgt ttctgagagc aaatgttact tgttccacgt ttcttccatg    600

tcagtttttc cccagggatt aaaaatgttg cttgaaaata aagcagttaa aaaggcaggt    660

gtaggaattg aaggagatca gtggaaactt ctacgtgact ttgatatcaa attgaagaat    720

tttgtggagt tgacagatgt tgccaataaa aagctgaaat gcacagagac ctggagcctt    780

aacagtctgg ttaaacacct cttaggtaaa cagctcctga aagacaagtc tatccgctgt    840

agcaattgga gtaaatttcc tctcactgag gaccagaaac tgtatgcagc cactgatgct    900

tatgctggtt ttattattta ccgaaattta gagattttgg atgatactgt gcaaaggttt    960

gctataaata aagaggaaga aatcctactt agcgacatga acaaacagtt gacttcaatc   1020

tctgaggaag tgatggatct ggctaagcat cttcctcatg ctttcagtaa attggaaaac   1080

ccacggaggg tttctatctt actaaaggat atttcagaaa atctatattc actgaggagg   1140

atgataattg ggtctactaa cattgagact gaactgaggc ccagcaataa tttaaactta   1200

ttatcctttg aagattcaac tactggggga gtacaacaga aacaaattag agaacatgaa   1260

gttttaattc acgttgaaga tgaaacatgg gacccaacac ttgatcattt agctaaacat   1320

gatggagaag atgtacttgg aaataaagtg gaacgaaaag aagatggatt tgaagatgga   1380

gtagaagaca acaaattgaa agagaatatg gaaagagctt gtttgatgtc gttagatatt   1440

acagaacatg aactccaaat tttggaacag cagtctcagg aagaatatct tagtgatatt   1500

gcttataaat ctactgagca tttatctccc aatgataatg aaaacgatac gtcctatgta   1560

attgagagtg atgaagattt agaaatggag atgcttaagc atttatctcc caatgataat   1620

gaaaacgata cgtcctatgt aattgagagt gatgaagatt tagaaatgga gatgcttaag   1680

tctttagaaa acctcaatag tggcacggta gaaccaactc attctaaatg cttaaaaatg   1740

gaaagaaatc tggcacccaa tgaagagcaa gttacttgcc tcaagatgta ctttggccat   1800

tccagtttta aaccagttca gtggaaagtg attcattcag tattagaaga aagaagagat   1860

aatgttgctg tcatggcaac tggatatgga aagagtttgt gcttccagta tccacctgtt   1920

tatgtaggca agattggcct tgttatctct ccccttattt ctctgatgga agaccaagtg   1980

ctacagctta aaatgtccaa catcccagct tgcttccttg gatcagcaca gtcagaaaat   2040

gttctaacag atattaaatt aggtaaatac cggattgtat acgtaactcc agaatactgt   2100

tcaggtaaca tgggcctgct ccagcaactt gaggctgata ttggtatcac gctcattgct   2160

gtggatgagg ctcactgtat ttctgagtgg gggcatgatt ttagggattc attcaggaag   2220

ttgggctccc taaagacagc actgccaatg gttccaatcg ttgcacttac tgctactgca   2280

agttcttcaa tccgggaaga cattgtacgt tgcttaaatc tgagaaatcc tcagatcacc   2340

tgtactggtt ttgatcgacc aaacctgtat ttagaagtta ggcgaaaaac agggaatatc   2400

cttcaggatc tgcagccatt tcttgtcaaa acaagttccc actgggaatt tgaaggtcca   2460

acaatcatct actgtccttc tagaaaaatg acacaacaag ttacaggtga acttaggaaa   2520

ctgaatctat cctgtggaac ataccatgcg ggcatgagtt ttagcacaag gaaagacatt   2580

catcataggt ttgtaagaga tgaaattcag tgtgtcatag ctaccatagc ttttggaatg   2640

ggcattaata aagctgacat tcgccaagtc attcattacg gtgctcctaa ggacatggaa   2700

tcatattatc aggagattgg tagagctggt cgtgatggac ttcaaagttc ttgtcacgtc   2760

ctctgggctc ctgcagacat taacttaaat aggcaccttc ttactgagat acgtaatgag   2820

aagtttcgat tatacaaatt aaagatgatg gcaaagatgg aaaaatatct tcattctagc   2880

agatgtagga gacaaatcat cttgtctcat tttgaggaca aacaagtaca aaaagcctcc   2940

ttgggaatta tgggaactga aaaatgctgt gataattgca ggtccagatt ggatcattgc   3000

tattccatgg atgactcaga ggatacatcc tgggactttg gtccacaagc atttaagctt   3060

ttgtctgctg tggacatctt aggcgaaaaa tttggaattg ggcttccaat tttatttctc   3120

cgaggatcta attctcagcg tcttgccgat caatatcgca ggcacagttt atttggcact   3180

ggcaaggatc aaacagagag ttggtggaag gctttttccc gtcagctgat cactgaggga   3240

ttcttggtag aagtttctcg gtataacaaa tttatgaaga tttgcgccct tacgaaaaag   3300

ggtagaaatt ggcttcataa agctaataca gaatctcaga gcctcatcct tcaagctaat   3360

gaagaattgt gtccaaagaa gttgcttctg cctagttcga aaactgtatc ttcgggcacc   3420

aaagagcatt gttataatca agtaccagtt gaattaagta cagagaagaa gtctaacttg   3480

gagaagttat attcttataa accatgtgat aagatttctt ctgggagtaa catttctaaa   3540

aaaagtatca tggtacagtc accagaaaaa gcttacagtt cctcacagcc tgttatttcg   3600

gcacaagagc aggagactca gattgtgtta tatggcaaat tggtagaagc taggcagaaa   3660

catgccaata aaatggatgt tcccccagct attctggcaa caaacaagat actggtggat   3720

atggccaaaa tgagaccaac tacggttgaa aacgtaaaaa ggattgatgg tgtttctgaa   3780

ggcaaagctg ccatgttggc ccctctgttg gaagtcatca aacatttctg ccaaacaaat   3840

agtgttcaga cagacctctt ttcaagtaca aaacctcaag aagaacagaa gacgagtctg   3900

gtagcaaaaa ataaaatatg cacactttca cagtctatgg ccatcacata ctctttattc   3960

caagaaaaga agatgccttt gaagagcata gctgagagca ggattctgcc tctcatgaca   4020

attggcatgc acttatccca agcggtgaaa gctggctgcc cccttgattt ggagcgagca   4080

ggcctgactc cagaggttca gaagattatt gctgatgtta tccgaaaccc tcccgtcaac   4140

tcagatatga gtaaaattag cctaatcaga atgttagttc ctgaaaacat tgacacgtac   4200

cttatccaca tggcaattga gatccttaaa catggtcctg acagcggact tcaaccttca   4260

tgtgatgtca acaaaaggag atgttttccc ggttctgaag agatctgttc aagttctaag   4320

agaagcaagg aagaagtagg catcaatact gagacttcat ctgcagagag aaagagacga   4380

ttacctgtgt ggtttgccaa aggaagtgat accagcaaga aattaatgga caaaacgaaa   4440

aggggaggtc tttttagtta agctggcaat taccagaaca attatgtttc ttgctgtatt   4500

ataagaggat agctatattt tatttctgaa gagtaaggag tagtattttg gcttaaaaat   4560

cattctaatt acaaagttca ctgtttattg aagaactggc atcttaaatc agccttccgc   4620

aattcatgta gtttctgggt cttctgggag cctacgtgag tacatcacct aacagaatat   4680

taaattagac ttcctgtaag attgctttaa gaaactgtta ctgtcctgtt ttctaatctc   4740

tttattaaaa cagtgtattt ggaaaatgtt atgtgctctg atttgatata gataacagat   4800

tagtagttac atggtaatta tgtgatataa aatattcata tattatcaaa attctgtttt   4860

gtaaatgtaa gaaagcatag ttattttaca aattgttttt actgtctttt gaagaagttc   4920

ttaaatacgt tgttaaatgg tattagttga ccagggcagt gaaaatgaaa ccgcattttg   4980

ggtgccatta aatagggaaa aaacatgtaa aaaatgtaaa atggagacca attgcactag   5040

gcaagtgtat attttgtatt ttatatacaa tttctattat ttttcaagta ataaaacaat   5100

gtttttcata ctgaatatta tatatatatt ttttagcttt catttactta attattttaa   5160

gtacctttat ttttccagga tgtcagaatt tgattctaat ctctcttatg tagcacatgt   5220

gacttaattt aaaacctata ctgtgacaca gagttgggta aacgatgatt atttaacttt   5280

aagcagttca ccatccattt caaagccttt gattggcttt tttgtaaata aaaataactt   5340

gttaagaaac aaatatatct gtcatagaag aactagaaaa tccagggaag tgagaaaaat   5400

gaaaataaaa atcattcata gttttactag tagctaatca cagtcaacct cttttgtgta   5460

tcccaccaga cttttttata ttcatttgtt tttagttaaa atataaaagt ctcgtatatt   5520

cccatttttc tgcattgcat taccagaagg tagtggcgcc tattaaatat gtgatatgtt   5580

gttgtccagc catggcttct gcatttgcat gcttttgtgt gtgcatctgc aataccctgt   5640

gaatatcctg tgtgatggag tggcaagtac gcacagacac gtctgctgca tgcctaggta   5700

cgaggctgtc tccaggagaa gcacttgttt gattatttga gttgccaatt gaatttgctg   5760

ctttttttca tggcttgcca ttttcactga aaagaatgac taatgaaaaa cgatgattgg   5820

ttattagatt tggatgtttg gcagacattt tctcaaaatt gaactaagtt ggcctcttca   5880

cggaaaacaa ctggtatttg ttgtgccaat gataaaattg gagatttcta gcaaaatgta   5940

taattttgga aaagttgtgt tcctccactg gaagcttgac agctttcctt aacataaaga   6000

cttctctttc tcttcgcttt cactactact actactaatt cttcttctga ttcttcttct   6060

tctccttctt ccttcttcct tccttcctcc tcctcctcct tcttcttcct cttcctcttc   6120

ttctttctct ctttccttcc ttcccttccc ttccccttcc ttc                     6163


<210>  5503
<211>  1403
<212>  PRT
<213>  Homo sapiens

<400>  5503

Met Ser Glu Lys Lys Leu Glu Thr Thr Ala Gln Gln Arg Lys Cys Pro 
1               5                   10                  15


Glu Trp Met Asn Val Gln Asn Lys Arg Cys Ala Val Glu Glu Arg Lys 
            20                  25                  30


Ala Cys Val Arg Lys Ser Val Phe Glu Asp Asp Leu Pro Phe Leu Glu 
        35                  40                  45


Phe Thr Gly Ser Ile Val Tyr Ser Tyr Asp Ala Ser Asp Cys Ser Phe 
    50                  55                  60


Leu Ser Glu Asp Ile Ser Met Ser Leu Ser Asp Gly Asp Val Val Gly 
65                  70                  75                  80


Phe Asp Met Glu Trp Pro Pro Leu Tyr Asn Arg Gly Lys Leu Gly Lys 
                85                  90                  95


Val Ala Leu Ile Gln Leu Cys Val Ser Glu Ser Lys Cys Tyr Leu Phe 
            100                 105                 110


His Val Ser Ser Met Ser Val Phe Pro Gln Gly Leu Lys Met Leu Leu 
        115                 120                 125


Glu Asn Lys Ala Val Lys Lys Ala Gly Val Gly Ile Glu Gly Asp Gln 
    130                 135                 140


Trp Lys Leu Leu Arg Asp Phe Asp Ile Lys Leu Lys Asn Phe Val Glu 
145                 150                 155                 160


Leu Thr Asp Val Ala Asn Lys Lys Leu Lys Cys Thr Glu Thr Trp Ser 
                165                 170                 175


Leu Asn Ser Leu Val Lys His Leu Leu Gly Lys Gln Leu Leu Lys Asp 
            180                 185                 190


Lys Ser Ile Arg Cys Ser Asn Trp Ser Lys Phe Pro Leu Thr Glu Asp 
        195                 200                 205


Gln Lys Leu Tyr Ala Ala Thr Asp Ala Tyr Ala Gly Phe Ile Ile Tyr 
    210                 215                 220


Arg Asn Leu Glu Ile Leu Asp Asp Thr Val Gln Arg Phe Ala Ile Asn 
225                 230                 235                 240


Lys Glu Glu Glu Ile Leu Leu Ser Asp Met Asn Lys Gln Leu Thr Ser 
                245                 250                 255


Ile Ser Glu Glu Val Met Asp Leu Ala Lys His Leu Pro His Ala Phe 
            260                 265                 270


Ser Lys Leu Glu Asn Pro Arg Arg Val Ser Ile Leu Leu Lys Asp Ile 
        275                 280                 285


Ser Glu Asn Leu Tyr Ser Leu Arg Arg Met Ile Ile Gly Ser Thr Asn 
    290                 295                 300


Ile Glu Thr Glu Leu Arg Pro Ser Asn Asn Leu Asn Leu Leu Ser Phe 
305                 310                 315                 320


Glu Asp Ser Thr Thr Gly Gly Val Gln Gln Lys Gln Ile Arg Glu His 
                325                 330                 335


Glu Val Leu Ile His Val Glu Asp Glu Thr Trp Asp Pro Thr Leu Asp 
            340                 345                 350


His Leu Ala Lys His Asp Gly Glu Asp Val Leu Gly Asn Lys Val Glu 
        355                 360                 365


Arg Lys Glu Asp Gly Phe Glu Asp Gly Val Glu Asp Asn Lys Leu Lys 
    370                 375                 380


Glu Asn Met Glu Arg Ala Cys Leu Met Ser Leu Asp Ile Thr Glu His 
385                 390                 395                 400


Glu Leu Gln Ile Leu Glu Gln Gln Ser Gln Glu Glu Tyr Leu Ser Asp 
                405                 410                 415


Ile Ala Tyr Lys Ser Thr Glu His Leu Ser Pro Asn Asp Asn Glu Asn 
            420                 425                 430


Asp Thr Ser Tyr Val Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met 
        435                 440                 445


Leu Lys His Leu Ser Pro Asn Asp Asn Glu Asn Asp Thr Ser Tyr Val 
    450                 455                 460


Ile Glu Ser Asp Glu Asp Leu Glu Met Glu Met Leu Lys Ser Leu Glu 
465                 470                 475                 480


Asn Leu Asn Ser Gly Thr Val Glu Pro Thr His Ser Lys Cys Leu Lys 
                485                 490                 495


Met Glu Arg Asn Leu Ala Pro Asn Glu Glu Gln Val Thr Cys Leu Lys 
            500                 505                 510


Met Tyr Phe Gly His Ser Ser Phe Lys Pro Val Gln Trp Lys Val Ile 
        515                 520                 525


His Ser Val Leu Glu Glu Arg Arg Asp Asn Val Ala Val Met Ala Thr 
    530                 535                 540


Gly Tyr Gly Lys Ser Leu Cys Phe Gln Tyr Pro Pro Val Tyr Val Gly 
545                 550                 555                 560


Lys Ile Gly Leu Val Ile Ser Pro Leu Ile Ser Leu Met Glu Asp Gln 
                565                 570                 575


Val Leu Gln Leu Lys Met Ser Asn Ile Pro Ala Cys Phe Leu Gly Ser 
            580                 585                 590


Ala Gln Ser Glu Asn Val Leu Thr Asp Ile Lys Leu Gly Lys Tyr Arg 
        595                 600                 605


Ile Val Tyr Val Thr Pro Glu Tyr Cys Ser Gly Asn Met Gly Leu Leu 
    610                 615                 620


Gln Gln Leu Glu Ala Asp Ile Gly Ile Thr Leu Ile Ala Val Asp Glu 
625                 630                 635                 640


Ala His Cys Ile Ser Glu Trp Gly His Asp Phe Arg Asp Ser Phe Arg 
                645                 650                 655


Lys Leu Gly Ser Leu Lys Thr Ala Leu Pro Met Val Pro Ile Val Ala 
            660                 665                 670


Leu Thr Ala Thr Ala Ser Ser Ser Ile Arg Glu Asp Ile Val Arg Cys 
        675                 680                 685


Leu Asn Leu Arg Asn Pro Gln Ile Thr Cys Thr Gly Phe Asp Arg Pro 
    690                 695                 700


Asn Leu Tyr Leu Glu Val Arg Arg Lys Thr Gly Asn Ile Leu Gln Asp 
705                 710                 715                 720


Leu Gln Pro Phe Leu Val Lys Thr Ser Ser His Trp Glu Phe Glu Gly 
                725                 730                 735


Pro Thr Ile Ile Tyr Cys Pro Ser Arg Lys Met Thr Gln Gln Val Thr 
            740                 745                 750


Gly Glu Leu Arg Lys Leu Asn Leu Ser Cys Gly Thr Tyr His Ala Gly 
        755                 760                 765


Met Ser Phe Ser Thr Arg Lys Asp Ile His His Arg Phe Val Arg Asp 
    770                 775                 780


Glu Ile Gln Cys Val Ile Ala Thr Ile Ala Phe Gly Met Gly Ile Asn 
785                 790                 795                 800


Lys Ala Asp Ile Arg Gln Val Ile His Tyr Gly Ala Pro Lys Asp Met 
                805                 810                 815


Glu Ser Tyr Tyr Gln Glu Ile Gly Arg Ala Gly Arg Asp Gly Leu Gln 
            820                 825                 830


Ser Ser Cys His Val Leu Trp Ala Pro Ala Asp Ile Asn Leu Asn Arg 
        835                 840                 845


His Leu Leu Thr Glu Ile Arg Asn Glu Lys Phe Arg Leu Tyr Lys Leu 
    850                 855                 860


Lys Met Met Ala Lys Met Glu Lys Tyr Leu His Ser Ser Arg Cys Arg 
865                 870                 875                 880


Arg Gln Ile Ile Leu Ser His Phe Glu Asp Lys Gln Val Gln Lys Ala 
                885                 890                 895


Ser Leu Gly Ile Met Gly Thr Glu Lys Cys Cys Asp Asn Cys Arg Ser 
            900                 905                 910


Arg Leu Asp His Cys Tyr Ser Met Asp Asp Ser Glu Asp Thr Ser Trp 
        915                 920                 925


Asp Phe Gly Pro Gln Ala Phe Lys Leu Leu Ser Ala Val Asp Ile Leu 
    930                 935                 940


Gly Glu Lys Phe Gly Ile Gly Leu Pro Ile Leu Phe Leu Arg Gly Ser 
945                 950                 955                 960


Asn Ser Gln Arg Leu Ala Asp Gln Tyr Arg Arg His Ser Leu Phe Gly 
                965                 970                 975


Thr Gly Lys Asp Gln Thr Glu Ser Trp Trp Lys Ala Phe Ser Arg Gln 
            980                 985                 990


Leu Ile Thr Glu Gly Phe Leu Val Glu Val Ser Arg Tyr Asn Lys Phe 
        995                 1000                1005


Met Lys Ile Cys Ala Leu Thr Lys Lys Gly Arg Asn Trp Leu His Lys 
    1010                1015                1020


Ala Asn Thr Glu Ser Gln Ser Leu Ile Leu Gln Ala Asn Glu Glu Leu 
1025                1030                1035                1040


Cys Pro Lys Lys Leu Leu Leu Pro Ser Ser Lys Thr Val Ser Ser Gly 
                1045                1050                1055


Thr Lys Glu His Cys Tyr Asn Gln Val Pro Val Glu Leu Ser Thr Glu 
            1060                1065                1070


Lys Lys Ser Asn Leu Glu Lys Leu Tyr Ser Tyr Lys Pro Cys Asp Lys 
        1075                1080                1085


Ile Ser Ser Gly Ser Asn Ile Ser Lys Lys Ser Ile Met Val Gln Ser 
    1090                1095                1100


Pro Glu Lys Ala Tyr Ser Ser Ser Gln Pro Val Ile Ser Ala Gln Glu 
1105                1110                1115                1120


Gln Glu Thr Gln Ile Val Leu Tyr Gly Lys Leu Val Glu Ala Arg Gln 
                1125                1130                1135


Lys His Ala Asn Lys Met Asp Val Pro Pro Ala Ile Leu Ala Thr Asn 
            1140                1145                1150


Lys Ile Leu Val Asp Met Ala Lys Met Arg Pro Thr Thr Val Glu Asn 
        1155                1160                1165


Val Lys Arg Ile Asp Gly Val Ser Glu Gly Lys Ala Ala Met Leu Ala 
    1170                1175                1180


Pro Leu Leu Glu Val Ile Lys His Phe Cys Gln Thr Asn Ser Val Gln 
1185                1190                1195                1200


Thr Asp Leu Phe Ser Ser Thr Lys Pro Gln Glu Glu Gln Lys Thr Ser 
                1205                1210                1215


Leu Val Ala Lys Asn Lys Ile Cys Thr Leu Ser Gln Ser Met Ala Ile 
            1220                1225                1230


Thr Tyr Ser Leu Phe Gln Glu Lys Lys Met Pro Leu Lys Ser Ile Ala 
        1235                1240                1245


Glu Ser Arg Ile Leu Pro Leu Met Thr Ile Gly Met His Leu Ser Gln 
    1250                1255                1260


Ala Val Lys Ala Gly Cys Pro Leu Asp Leu Glu Arg Ala Gly Leu Thr 
1265                1270                1275                1280


Pro Glu Val Gln Lys Ile Ile Ala Asp Val Ile Arg Asn Pro Pro Val 
                1285                1290                1295


Asn Ser Asp Met Ser Lys Ile Ser Leu Ile Arg Met Leu Val Pro Glu 
            1300                1305                1310


Asn Ile Asp Thr Tyr Leu Ile His Met Ala Ile Glu Ile Leu Lys His 
        1315                1320                1325


Gly Pro Asp Ser Gly Leu Gln Pro Ser Cys Asp Val Asn Lys Arg Arg 
    1330                1335                1340


Cys Phe Pro Gly Ser Glu Glu Ile Cys Ser Ser Ser Lys Arg Ser Lys 
1345                1350                1355                1360


Glu Glu Val Gly Ile Asn Thr Glu Thr Ser Ser Ala Glu Arg Lys Arg 
                1365                1370                1375


Arg Leu Pro Val Trp Phe Ala Lys Gly Ser Asp Thr Ser Lys Lys Leu 
            1380                1385                1390


Met Asp Lys Thr Lys Arg Gly Gly Leu Phe Ser 
        1395                1400


<210>  5504
<211>  3592
<212>  DNA
<213>  Homo sapiens

<400>  5504
gtagtatggc ttgcacatct gccagctttc gacaaaattg taggccctgt taataatagt     60

ccttttgtgt ttggtgaaaa agatacgaca ctgtcagtgg ttttgctttt aagatttctt    120

ttaaactttc agtctttaga aaacctcaat agtggcacgg tagaaccaac tcattctaaa    180

tgcttaaaaa tggaaagaaa tctgggtctt cctactaaag aagaagaaga agatgatgaa    240

aatgaagcta atgaagggga agaagatgat gataaggact ttttgtggcc agcacccaat    300

gaagagcaag ttacttgcct caagatgtac tttggccatt ccagttttaa accgatatgg    360

aaagagtttg tgcttccagt atccacctgt ttatgtaggc aagattggcc ttgttatctc    420

tccccttatt tctctgatgg aagaccaagt gctacagctt aaaatgtcca acatcccagc    480

ttgcttcctt ggatcagcac agtcagaaaa tgttctaaca gatattaaat taggtaaata    540

ccggattgta tacgtaactc cagaatactg ttcaggtaac atgggcctgc tccagcaact    600

tgaggctgat attggtatca cgctcattgc tgtggatgag gctcactgta tttctgagtg    660

ggggcatgat tttagggatt cattcaggaa gttgggctcc ctaaagacag cactgccaat    720

ggttccaatc gttgcactta ctgctactgc aagttcttca atccgggaag acattgtacg    780

ttgcttaaat ctgagaaatc ctcagatcac ctgtactggt tttgatcgac caaacctgta    840

tttagaagtt aggcgaaaaa cagggaatat ccttcaggat ctgcagccat ttcttgtcaa    900

aacaagttcc cactgggaat ttgaaggtcc aacaatcatc tactgtcctt ctagaaaaat    960

gacacaacaa gttacaggtg aacttaggaa actgaatcta tcctgtggaa cataccatgc   1020

gggcatgagt tttagcacaa ggaaagacat tcatcatagg tttgtaagag atgaaattca   1080

gtgtgtcata gctaccatag cttttggaat gggcattaat aaagctgaca ttcgccaagt   1140

cattcattac ggtgctccta aggacatgga atcatattat caggagattg gtagagctgg   1200

tcgtgatgga cttcaaagtt cttgtcacgt cctctgggct cctgcagaca ttaacttaaa   1260

taggcacctt cttactgaga tacgtaatga gaagtttcga ttatacaaat taaagatgat   1320

ggcaaagatg gaaaaatatc ttcattctag cagatgtagg agacaaatca tcttgtctca   1380

ttttgaggac aaacaagtac aaaaagcctc cttgggaatt atgggaactg aaaaatgctg   1440

tgataattgc aggtccagat tggatcattg ctattccatg gatgactcag aggatacatc   1500

ctgggacttt ggtccacaag catttaagct tttgtctgct gtggacatct taggcgaaaa   1560

atttggaatt gggcttccaa ttttatttct ccgaggatct aattctcagc gtcttgccga   1620

tcaatatcgc aggcacagtt tatttggcac tggcaaggat caaacagaga gttggtggaa   1680

ggctttttcc cgtcagctga tcactgaggg attcttggta gaagtttctc ggtataacaa   1740

atttatgaag atttgcgccc ttacgaaaaa gggtagaaat tggcttcata aagctaatac   1800

agaatctcag agcctcatcc ttcaagctaa tgaagaattg tgtccaaaga agttgcttct   1860

gcctagttcg aaaactgtat cttcgggcac caaagagcat tgttataatc aagtaccagt   1920

tgaattaagt acagagaaga agtctaactt ggagaagtta tattcttata aaccatgtga   1980

taagatttct tctgggagta acatttctaa aaaaagtatc atggtacagt caccagaaaa   2040

agcttacagt tcctcacagc ctgttatttc ggcacaagag caggagactc agattgtgtt   2100

atatggcaaa ttggtagaag ctaggcagaa acatgccaat aaaatggatg ttcccccagc   2160

tattctggca acaaacaaga tactggtgga tatggccaaa atgagaccaa ctacggttga   2220

aaacgtaaaa aggattgatg gtgtttctga aggcaaagct gccatgttgg cccctctgtt   2280

ggaagtcatc aaacatttct gccaaacaaa tagtgttcag acagacctct tttcaagtac   2340

aaaacctcaa gaagaacaga agacgagtct ggtagcaaaa aataaaatat gcacactttc   2400

acagtctatg gccatcacat actctttatt ccaagaaaag aagatgcctt tgaagagcat   2460

agctgagagc aggattctgc ctctcatgac aattggcatg cacttatccc aagcggtgaa   2520

agctggctgc ccccttgatt tggagcgagc aggcctgact ccagaggttc agaagattat   2580

tgctgatgtt atccgaaacc ctcccgtcaa ctcagatatg agtaaaatta gcctaatcag   2640

aatgttagtt cctgaaaaca ttgacacgta ccttatccac atggcaattg agatccttaa   2700

acatggtcct gacagcggac ttcaaccttc atgtgatgtc aacaaaagga gatgttttcc   2760

cggttctgaa gagatctgtt caagttctaa gagaagcaag gaagaagtag gcatcaatac   2820

tgagacttca tctgcagaga gaaagagacg attacctgtg tggtttgcca aaggaagtga   2880

taccagcaag aaattaatgg acaaaacgaa aaggggaggt ctttttagtt aagctggcaa   2940

ttaccagaac aattatgttt cttgctgtat tataagagga tagctatatt ttatttctga   3000

agagtaagga gtagtatttt ggcttaaaaa tcattctaat tacaaagttc actgtttatt   3060

gaagaactgg catcttaaat cagccttccg caattcatgt agtttctggg tcttctggga   3120

gcctacgtga gtacatcacc taacagaata ttaaattaga cttcctgtaa gattgcttta   3180

agaaactgtt actgtcctgt tttctaatct ctttattaaa acagtgtatt tggaaaatgt   3240

tatgtgctct gatttgatat agataacaga ttagtagtta catggtaatt atgtgatata   3300

aaatattcat atattatcaa aattctgttt tgtaaatgta agaaagcata gttattttac   3360

aaattgtttt tactgtcttt tgaagaagtt cttaaatacg ttgttaaatg gtattagttg   3420

accagggcag tgaaaatgaa accgcatttt gggtgccatt aaatagggaa aaaacatgta   3480

aaaaatgtaa aatggagacc aattgcacta ggcaagtgta tattttgtat tttatataca   3540

atttctatta tttttcaagt aataaaacaa tgtttttcat actgaatatt at           3592


<210>  5505
<211>  899
<212>  PRT
<213>  Homo sapiens

<400>  5505

Met Met Lys Met Lys Leu Met Lys Gly Lys Lys Met Met Ile Arg Thr 
1               5                   10                  15


Phe Cys Gly Gln His Pro Met Lys Ser Lys Leu Leu Ala Ser Arg Cys 
            20                  25                  30


Thr Leu Ala Ile Pro Val Leu Asn Arg Tyr Gly Lys Ser Leu Cys Phe 
        35                  40                  45


Gln Tyr Pro Pro Val Tyr Val Gly Lys Ile Gly Leu Val Ile Ser Pro 
    50                  55                  60


Leu Ile Ser Leu Met Glu Asp Gln Val Leu Gln Leu Lys Met Ser Asn 
65                  70                  75                  80


Ile Pro Ala Cys Phe Leu Gly Ser Ala Gln Ser Glu Asn Val Leu Thr 
                85                  90                  95


Asp Ile Lys Leu Gly Lys Tyr Arg Ile Val Tyr Val Thr Pro Glu Tyr 
            100                 105                 110


Cys Ser Gly Asn Met Gly Leu Leu Gln Gln Leu Glu Ala Asp Ile Gly 
        115                 120                 125


Ile Thr Leu Ile Ala Val Asp Glu Ala His Cys Ile Ser Glu Trp Gly 
    130                 135                 140


His Asp Phe Arg Asp Ser Phe Arg Lys Leu Gly Ser Leu Lys Thr Ala 
145                 150                 155                 160


Leu Pro Met Val Pro Ile Val Ala Leu Thr Ala Thr Ala Ser Ser Ser 
                165                 170                 175


Ile Arg Glu Asp Ile Val Arg Cys Leu Asn Leu Arg Asn Pro Gln Ile 
            180                 185                 190


Thr Cys Thr Gly Phe Asp Arg Pro Asn Leu Tyr Leu Glu Val Arg Arg 
        195                 200                 205


Lys Thr Gly Asn Ile Leu Gln Asp Leu Gln Pro Phe Leu Val Lys Thr 
    210                 215                 220


Ser Ser His Trp Glu Phe Glu Gly Pro Thr Ile Ile Tyr Cys Pro Ser 
225                 230                 235                 240


Arg Lys Met Thr Gln Gln Val Thr Gly Glu Leu Arg Lys Leu Asn Leu 
                245                 250                 255


Ser Cys Gly Thr Tyr His Ala Gly Met Ser Phe Ser Thr Arg Lys Asp 
            260                 265                 270


Ile His His Arg Phe Val Arg Asp Glu Ile Gln Cys Val Ile Ala Thr 
        275                 280                 285


Ile Ala Phe Gly Met Gly Ile Asn Lys Ala Asp Ile Arg Gln Val Ile 
    290                 295                 300


His Tyr Gly Ala Pro Lys Asp Met Glu Ser Tyr Tyr Gln Glu Ile Gly 
305                 310                 315                 320


Arg Ala Gly Arg Asp Gly Leu Gln Ser Ser Cys His Val Leu Trp Ala 
                325                 330                 335


Pro Ala Asp Ile Asn Leu Asn Arg His Leu Leu Thr Glu Ile Arg Asn 
            340                 345                 350


Glu Lys Phe Arg Leu Tyr Lys Leu Lys Met Met Ala Lys Met Glu Lys 
        355                 360                 365


Tyr Leu His Ser Ser Arg Cys Arg Arg Gln Ile Ile Leu Ser His Phe 
    370                 375                 380


Glu Asp Lys Gln Val Gln Lys Ala Ser Leu Gly Ile Met Gly Thr Glu 
385                 390                 395                 400


Lys Cys Cys Asp Asn Cys Arg Ser Arg Leu Asp His Cys Tyr Ser Met 
                405                 410                 415


Asp Asp Ser Glu Asp Thr Ser Trp Asp Phe Gly Pro Gln Ala Phe Lys 
            420                 425                 430


Leu Leu Ser Ala Val Asp Ile Leu Gly Glu Lys Phe Gly Ile Gly Leu 
        435                 440                 445


Pro Ile Leu Phe Leu Arg Gly Ser Asn Ser Gln Arg Leu Ala Asp Gln 
    450                 455                 460


Tyr Arg Arg His Ser Leu Phe Gly Thr Gly Lys Asp Gln Thr Glu Ser 
465                 470                 475                 480


Trp Trp Lys Ala Phe Ser Arg Gln Leu Ile Thr Glu Gly Phe Leu Val 
                485                 490                 495


Glu Val Ser Arg Tyr Asn Lys Phe Met Lys Ile Cys Ala Leu Thr Lys 
            500                 505                 510


Lys Gly Arg Asn Trp Leu His Lys Ala Asn Thr Glu Ser Gln Ser Leu 
        515                 520                 525


Ile Leu Gln Ala Asn Glu Glu Leu Cys Pro Lys Lys Leu Leu Leu Pro 
    530                 535                 540


Ser Ser Lys Thr Val Ser Ser Gly Thr Lys Glu His Cys Tyr Asn Gln 
545                 550                 555                 560


Val Pro Val Glu Leu Ser Thr Glu Lys Lys Ser Asn Leu Glu Lys Leu 
                565                 570                 575


Tyr Ser Tyr Lys Pro Cys Asp Lys Ile Ser Ser Gly Ser Asn Ile Ser 
            580                 585                 590


Lys Lys Ser Ile Met Val Gln Ser Pro Glu Lys Ala Tyr Ser Ser Ser 
        595                 600                 605


Gln Pro Val Ile Ser Ala Gln Glu Gln Glu Thr Gln Ile Val Leu Tyr 
    610                 615                 620


Gly Lys Leu Val Glu Ala Arg Gln Lys His Ala Asn Lys Met Asp Val 
625                 630                 635                 640


Pro Pro Ala Ile Leu Ala Thr Asn Lys Ile Leu Val Asp Met Ala Lys 
                645                 650                 655


Met Arg Pro Thr Thr Val Glu Asn Val Lys Arg Ile Asp Gly Val Ser 
            660                 665                 670


Glu Gly Lys Ala Ala Met Leu Ala Pro Leu Leu Glu Val Ile Lys His 
        675                 680                 685


Phe Cys Gln Thr Asn Ser Val Gln Thr Asp Leu Phe Ser Ser Thr Lys 
    690                 695                 700


Pro Gln Glu Glu Gln Lys Thr Ser Leu Val Ala Lys Asn Lys Ile Cys 
705                 710                 715                 720


Thr Leu Ser Gln Ser Met Ala Ile Thr Tyr Ser Leu Phe Gln Glu Lys 
                725                 730                 735


Lys Met Pro Leu Lys Ser Ile Ala Glu Ser Arg Ile Leu Pro Leu Met 
            740                 745                 750


Thr Ile Gly Met His Leu Ser Gln Ala Val Lys Ala Gly Cys Pro Leu 
        755                 760                 765


Asp Leu Glu Arg Ala Gly Leu Thr Pro Glu Val Gln Lys Ile Ile Ala 
    770                 775                 780


Asp Val Ile Arg Asn Pro Pro Val Asn Ser Asp Met Ser Lys Ile Ser 
785                 790                 795                 800


Leu Ile Arg Met Leu Val Pro Glu Asn Ile Asp Thr Tyr Leu Ile His 
                805                 810                 815


Met Ala Ile Glu Ile Leu Lys His Gly Pro Asp Ser Gly Leu Gln Pro 
            820                 825                 830


Ser Cys Asp Val Asn Lys Arg Arg Cys Phe Pro Gly Ser Glu Glu Ile 
        835                 840                 845


Cys Ser Ser Ser Lys Arg Ser Lys Glu Glu Val Gly Ile Asn Thr Glu 
    850                 855                 860


Thr Ser Ser Ala Glu Arg Lys Arg Arg Leu Pro Val Trp Phe Ala Lys 
865                 870                 875                 880


Gly Ser Asp Thr Ser Lys Lys Leu Met Asp Lys Thr Lys Arg Gly Gly 
                885                 890                 895


Leu Phe Ser 



<210>  5506
<211>  2128
<212>  DNA
<213>  Homo sapiens

<400>  5506
gatgggctcc tctcctgagt gggaaggcaa ggaaataggg gcttaccacc caaaagatgg     60

gaggcagaag atacccacct gagttgccca gagcccacag tgtttgcttt ctcaccactc    120

cggactccac ctttgagctc tttgcgagag atgtggattt ccagctttga acaatccaag    180

aaagaagccc aggcactaag cttattggta tttggcaaac ctggtatcct gcagccgagc    240

atgaacatga aatacattag aacttggcaa tgagagatcc catctgttgg tttccaggga    300

tgtaagtgag taataaaagc tgtttcaagt ttatccacta tccactcttc aagtgaaaag    360

aacttatgtg tgtctacctt cttctccata ccctgagcca cctctctcac tttctttagt    420

tgtgccttgc cctatcgcct cccattttcc cttcaaagta gaatgtcttg taaagacaca    480

gtaactcctg tgtgttttga ttagtgagat gttaccactt accccttctg ctgcgcagaa    540

taatattaag aattgctatg cttatgattc aggctggaca gcctggacat tttgagcagc    600

gcgagagtag aagtgaatac ccccaggaac tccaattgtg ctgaagctga tttgtctgtt    660

cgtaggatga tgtgcagcct gtcacagtgg cagccacagg cattcagttt gtgggcattt    720

cctgtcattt cggatcctgc tatagggaag gttcagctct cctgtctggg gcatctactg    780

gagcacctca gaagacaagg aggaaaacac tggctcatgt tttctttcca tgtgagggag    840

gggaggtttc tagatgatac taaaagcctg ttgccactgt tgtgtcatga tttccattct    900

tcatcatgga aagccacaag cctcagaagg cagccagagg acaggaagag tctgtgatgc    960

tcatgtctgt gtcatggcat gagggggaat tgacgagtgc ttgcttagca tcagctctca   1020

ttgtattgaa ggctgtgccc ttggtgtgct tagcagtgag cagcgtcttc attaggtagc   1080

tctggctggg ctttgtcagc cagcgtgtga gaaaggagaa ccaaaaccaa tacctcctta   1140

tagaagccag aaggatcaca ttggatgaga gaaggtgtct ataactgggt tcttcccaat   1200

cccagctctt tcattaacta aatatgatct tggacatatc tcttaacctc catcggcctt   1260

agtttttgca tccaaaaaga agtgattggg ctggtcttgg aaggtttttt tctttttttt   1320

cccctgtgta acattcttca ttgttcatca acatttaaga aatttaattt tgtagatgtt   1380

tttactaaag agggtaacaa actattttgg aactgctgta tgttattcaa gggaagcacg   1440

ctgtttggag gaaggagcat acttaatggg tagtattgag gatgaaaggg aatttctctc   1500

tctgccattt tatttgataa tattaaagaa ataaagactg gaaaggggga ttccttgtta   1560

aaggtcagat tttaaattgc atataaaatg aagtgagttg tgtttttttg aaccctcaaa   1620

agaaagcctg agaggtgatt tatgcctctg gcaaggtatt atcatgataa cttcagttct   1680

tctccataaa tgccttcagc aaatacccag tgcttatgtg ctgtgtgtat gtcttaaacc   1740

ttaactttca tgaaatctca ttccatctta gttcttcatc aagtccatag ataaaatcct   1800

ctctaagcgt ttctgaagta tgtatccctg aacaaattta gtgaaataaa atcattaatc   1860

tgtgttgatc ccattttgcc atacctttca ctttacctca ctgtctcctt ttgtgaaata   1920

ttttaagaaa gcaacgtccc tcacaggact gttttgagga atgcctcatg gctgtgaagg   1980

agtttgtaca atgcaacatt ttgcttagcc cttcagtaca ttttacttgg attgttttca   2040

agaactttat tttttttgag aagaagtctt gctctatcac ctaggctgga gtgcagtggt   2100

gcgatctcag ctcactgcaa cctccacc                                      2128


<210>  5507
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  5507

Met Trp Ile Ser Ser Phe Glu Gln Ser Lys Lys Glu Ala Gln Ala Leu 
1               5                   10                  15


Ser Leu Leu Val Phe Gly Lys Pro Gly Ile Leu Gln Pro Ser Met Asn 
            20                  25                  30


Met Lys Tyr Ile Arg Thr Trp Gln 
        35                  40


<210>  5508
<211>  3892
<212>  DNA
<213>  Homo sapiens

<400>  5508
agaatttttt tgattccttc ttatttggag aaatctccag ctgctctgat gatagcctaa     60

gaagactgca tgctgcttcc tctcgatgcc aagccagacc ctctcacaac ctcggatctc    120

agtccttcat ggagacctgg tcccagcagg aatggcagtg caggaaattg gcgcccagat    180

ggttcttcca tgtgaagttg tctcgggctc tgggctgacg agagaacacc tggtaaccag    240

gtcatggttg agctggggaa gtttgaaagg aaggagttta aaagttccag tttgcaagat    300

ggacatacaa aaatggagga agcacctacg catcttaatt catttcttaa gaaagaagga    360

ttgaccttca acaggaaaag aaaatgggaa ttggacagct accccattat gctctggtgg    420

tccccgctga cgggggagac tgggaggtta ggccaatgtg gagcagatgc ttgtttcttc    480

accatcaacc ggacctacct ccatcatcac atgaccaaag cattcctctt ctatggtact    540

gactttaaca tagatagctt acctctgcct cggaaagccc atcatgactg ggctgttttt    600

catgaagagt ccccgaaaaa caattataag ctctttcata aaccagtgat caccttgttc    660

aactacactg ccacgttcag caggcattcc cacttgccac taactaccca atacttggag    720

agcattgaag tcctgaagtc actccgatac ctagttcctt tgcagtccaa aaacaagctt    780

agaaaaagac ttgctccgct ggtgtatgta cagtcagact gtgacccacc atcagacagg    840

gacagctatg ttcgcgagct gatgacttac atcgaggtcg attcctatgg tgaatgttta    900

cgaaacaaag acctccctca gcagctgaaa aatccagcct ctatggatgc cgatggcttt    960

tataggatca ttgcacagta taagtttatc ctagcttttg agaatgcagt ttgtgatgac   1020

tacatcactg agaagttctg gaggccactg aaactggggg tagtccctgt atattacgga   1080

tcccccagca tcacagactg gcttccaagt aacaaaagtg ctattcttgt atcagaattt   1140

tctcacccca gggaactggc aagttacatc agacgactgg attctgatga cagattgtat   1200

gaggcctatg tagaatggaa gctgaagggt gagatctcta accagcgact tctgacagct   1260

ctcagggaac ggaaatgggg agtgcaagac gtcaaccagg acaattacat cgatgcattt   1320

gagtgtatgg tgtgcaccaa ggtgtgggct aatatcaggc ttcaggaaaa gggcttacca   1380

cccaaaagat gggaggcaga agatacccac ctgagttgcc cagagcccac agtgtttgct   1440

ttctcaccac tccggactcc acctttgagc tctttgcgag agatgtggat ttccagcttt   1500

gaacaatcca agaaagaagc ccaggcacta aggtggctgg ttgataggaa tcaaaacttt   1560

tcatctcaag agttttgggg cctagtattc aaggactgat ttcaaaaatg atcagaatga   1620

aacagactag agccttcttg aggtttattt tctaggttgc cttaatattt gaacataata   1680

gctattctgt tgactatcca tcaggataat aattagttgc tgcagtactc ataatgagcc   1740

ctttcaagga atagatgtaa attaccctta ggggtagcca ctatattttt tatactaaaa   1800

aaggaaatat ttcttatgga cactggttat cttccatgtc cgtgtctgtg gacccacata   1860

cttactgcct tttgtggaaa ttcacctaga gtgagtactt tccttgtgca atggagggag   1920

acgatctagc tatagattct tgatactcac ctcactctca acagcttatt ggtatttggc   1980

aaacctggta tcctgcagcc gagcatgaac atgaaataca ttagaacttg gcaatgagag   2040

atcccatctg ttggtttcca gggatgtaag tgagtaataa aagctgtttc aagtttatcc   2100

actatccact cttcaagtga aaagaactta tgtgtgtcta ccttcttctc cataccctga   2160

gccacctctc tcactttctt tagttgtgcc ttgccctatc gcctcccatt ttcccttcaa   2220

agtagaatgt cttgtaaaga cacagtaact cctgtgtgtt ttgattagtg agatgttacc   2280

acttacccct tctgctgcgc agaataatat taagaattgc tatgcttatg attcaggctg   2340

gacagcctgg acattttgag cagcgcgaga gtagaagtga atacccccag gaactccaat   2400

tgtgctgaag ctgatttgtc tgttcgtagg atgatgtgca gcctgtcaca gtggcagcca   2460

caggcattca gtttgtgggc atttcctgtc atttcggatc ctgctatagg gaaggttcag   2520

ctctcctgtc tggggcatct actggagcac ctcagaagac aaggaggaaa acactggctc   2580

atgttttctt tccatgtgag ggaggggagg tttctagatg atactaaaag cctgttgcca   2640

ctgttgtgtc atgatttcca ttcttcatca tggaaagcca caagcctcag aaggcagcca   2700

gaggacagga agagtctgtg atgctcatgt ctgtgtcatg gcatgagggg gaattgacga   2760

gtgcttgctt agcatcagct ctcattgtat tgaaggctgt gcccttggtg tgcttagcag   2820

tgagcagcgt cttcattagg tagctctggc tgggctttgt cagccagcgt gtgagaaagg   2880

agaaccaaaa ccaatacctc cttatagaag ccagaaggat cacattggat gagagaaggt   2940

gtctataact gggttcttcc caatcccagc tctttcatta actaaatatg atcttggaca   3000

tatctcttaa cctccatcgg ccttagtttt tgcatccaaa aagaagtgat tgggctggtc   3060

ttggaaggtt tttttctttt ttttcccctg tgtaacattc ttcattgttc atcaacattt   3120

aagaaattta attttgtaga tgtttttact aaagagggta acaaactatt ttggaactgc   3180

tgtatgttat tcaagggaag cacgctgttt ggaggaagga gcatacttaa tgggtagtat   3240

tgaggatgaa agggaatttc tctctctgcc attttatttg ataatattaa agaaataaag   3300

actggaaagg gggattcctt gttaaaggtc agattttaaa ttgcatataa aatgaagtga   3360

gttgtgtttt tttgaaccct caaaagaaag cctgagaggt gatttatgcc tctggcaagg   3420

tattatcatg ataacttcag ttcttctcca taaatgcctt cagcaaatac ccagtgctta   3480

tgtgctgtgt gtatgtctta aaccttaact ttcatgaaat ctcattccat cttagttctt   3540

catcaagtcc atagataaaa tcctctctaa gcgtttctga agtatgtatc cctgaacaaa   3600

tttagtgaaa taaaatcatt aatctgtgtt gatcccattt tgccatacct ttcactttac   3660

ctcactgtct ccttttgtga aatattttaa gaaagcaacg tccctcacag gactgttttg   3720

aggaatgcct catggctgtg aaggagtttg tacaatgcaa cattttgctt agcccttcag   3780

tacattttac ttggattgtt ttcaagaact ttattttttt tgagaagaag tcttgctcta   3840

tcacctaggc tggagtgcag tggtgcgatc tcagctcact gcaacctcca cc           3892


<210>  5509
<211>  451
<212>  PRT
<213>  Homo sapiens

<400>  5509

Met Val Glu Leu Gly Lys Phe Glu Arg Lys Glu Phe Lys Ser Ser Ser 
1               5                   10                  15


Leu Gln Asp Gly His Thr Lys Met Glu Glu Ala Pro Thr His Leu Asn 
            20                  25                  30


Ser Phe Leu Lys Lys Glu Gly Leu Thr Phe Asn Arg Lys Arg Lys Trp 
        35                  40                  45


Glu Leu Asp Ser Tyr Pro Ile Met Leu Trp Trp Ser Pro Leu Thr Gly 
    50                  55                  60


Glu Thr Gly Arg Leu Gly Gln Cys Gly Ala Asp Ala Cys Phe Phe Thr 
65                  70                  75                  80


Ile Asn Arg Thr Tyr Leu His His His Met Thr Lys Ala Phe Leu Phe 
                85                  90                  95


Tyr Gly Thr Asp Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala 
            100                 105                 110


His His Asp Trp Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr 
        115                 120                 125


Lys Leu Phe His Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr 
    130                 135                 140


Phe Ser Arg His Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser 
145                 150                 155                 160


Ile Glu Val Leu Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys 
                165                 170                 175


Asn Lys Leu Arg Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp 
            180                 185                 190


Cys Asp Pro Pro Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr 
        195                 200                 205


Tyr Ile Glu Val Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu 
    210                 215                 220


Pro Gln Gln Leu Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr 
225                 230                 235                 240


Arg Ile Ile Ala Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val 
                245                 250                 255


Cys Asp Asp Tyr Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly 
            260                 265                 270


Val Val Pro Val Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro 
        275                 280                 285


Ser Asn Lys Ser Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu 
    290                 295                 300


Leu Ala Ser Tyr Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu 
305                 310                 315                 320


Ala Tyr Val Glu Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu 
                325                 330                 335


Leu Thr Ala Leu Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln 
            340                 345                 350


Asp Asn Tyr Ile Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp 
        355                 360                 365


Ala Asn Ile Arg Leu Gln Glu Lys Gly Leu Pro Pro Lys Arg Trp Glu 
    370                 375                 380


Ala Glu Asp Thr His Leu Ser Cys Pro Glu Pro Thr Val Phe Ala Phe 
385                 390                 395                 400


Ser Pro Leu Arg Thr Pro Pro Leu Ser Ser Leu Arg Glu Met Trp Ile 
                405                 410                 415


Ser Ser Phe Glu Gln Ser Lys Lys Glu Ala Gln Ala Leu Arg Trp Leu 
            420                 425                 430


Val Asp Arg Asn Gln Asn Phe Ser Ser Gln Glu Phe Trp Gly Leu Val 
        435                 440                 445


Phe Lys Asp 
    450


<210>  5510
<211>  4357
<212>  DNA
<213>  Homo sapiens

<400>  5510
cctagtccag ttggagaagc ggagagtttc ccctgtctta aagaagaggg cccccgcagc     60

cttcccgaga actttccata gggccgtggc ctcaggcgga ctgcgaacca agatcatcag    120

cagggggcgg cccggtgttc ttagaacccg ggtcccaaga gcttgtgaac agggcacgag    180

tgaaaacccg gatccaggct ggctccgccg gaacgcgccc cgagctcgcc cgcgcggccg    240

cctcttccgc tcctgatcgg ctcttcgggt cttcccggcg cccaggcttg ggctcatagg    300

gagaaaggaa gctgcgctgc attctgcggg acgaaccctg ctccgcgcga gaattttttt    360

gattccttct tatttggaga aatctccagc tgctctgatg atagcctaag aagactgcat    420

gctgcttcct ctcgatgcca agccagaccc tctcacaacc tcggatctca gtccttcatg    480

gagacctggt cccagcagga atggcagtgc aggaaattgg cgcccagatg gttcttccat    540

gtgaagttgt ctcgggctct gggctgacga gagaacacct ggtaaccagg ttagccctct    600

gtcagtcacc cagggcaggg cagcatggtg cggattcaga ggaggaagct tttggcatct    660

tgcctgtgcg tcacagccac cgtctttctg cttgtcacac tccaggtcat ggttgagctg    720

gggaagtttg aaaggaagga gtttaaaagt tccagtttgc aagatggaca tacaaaaatg    780

gaggaagcac ctacgcatct taattcattt cttaagaaag aaggattgac cttcaacagg    840

aaaagaaaat gggaattgga cagctacccc attatgctct ggtggtcccc gctgacgggg    900

gagactggga ggttaggcca atgtggagca gatgcttgtt tcttcaccat caaccggacc    960

tacctccatc atcacatgac caaagcattc ctcttctatg gtactgactt taacatagat   1020

agcttacctc tgcctcggaa agcccatcat gactgggctg tttttcatga agagtccccg   1080

aaaaacaatt ataagctctt tcataaacca gtgatcacct tgttcaacta cactgccacg   1140

ttcagcaggc attcccactt gccactaact acccaatact tggagagcat tgaagtcctg   1200

aagtcactcc gatacctagt tcctttgcag tccaaaaaca agcttagaaa aagacttgct   1260

ccgctggtgt atgtacagtc agactgtgac ccaccatcag acagggacag ctatgttcgc   1320

gagctgatga cttacatcga ggtcgattcc tatggtgaat gtttacgaaa caaagacctc   1380

cctcagcagc tgaaaaatcc agcctctatg gatgccgatg gcttttatag gatcattgca   1440

cagtataagt ttatcctagc ttttgagaat gcagtttgtg atgactacat cactgagaag   1500

ttctggaggc cactgaaact gggggtagtc cctgtatatt acggatcccc cagcatcaca   1560

gactggcttc caagtaacaa aagtgctatt cttgtatcag aattttctca ccccagggaa   1620

ctggcaagtt acatcagacg actggattct gatgacagat tgtatgaggc ctatgtagaa   1680

tggaagctga agggtgagat ctctaaccag cgacttctga cagctctcag ggaacggaaa   1740

tggggagtgc aagacgtcaa ccaggacaat tacatcgatg catttgagtg tatggtgtgc   1800

accaaggtgt gggctaatat caggcttcag gaaaagggct taccacccaa aagatgggag   1860

gcagaagata cccacctgag ttgcccagag cccacagtgt ttgctttctc accactccgg   1920

actccacctt tgagctcttt gcgagagatg tggatttcca gctttgaaca atccaagaaa   1980

gaagcccagg cactaaggtg gctggttgat aggaatcaaa acttttcatc tcaagagttt   2040

tggggcctag tattcaagga ctgatttcaa aaatgatcag aatgaaacag actagagcct   2100

tcttgaggtt tattttctag gttgccttaa tatttgaaca taatagctat tctgttgact   2160

atccatcagg ataataatta gttgctgcag tactcataat gagccctttc aaggaataga   2220

tgtaaattac ccttaggggt agccactata ttttttatac taaaaaagga aatatttctt   2280

atggacactg gttatcttcc atgtccgtgt ctgtggaccc acatacttac tgccttttgt   2340

ggaaattcac ctagagtgag tactttcctt gtgcaatgga gggagacgat ctagctatag   2400

attcttgata ctcacctcac tctcaacagc ttattggtat ttggcaaacc tggtatcctg   2460

cagccgagca tgaacatgaa atacattaga acttggcaat gagagatccc atctgttggt   2520

ttccagggat gtaagtgagt aataaaagct gtttcaagtt tatccactat ccactcttca   2580

agtgaaaaga acttatgtgt gtctaccttc ttctccatac cctgagccac ctctctcact   2640

ttctttagtt gtgccttgcc ctatcgcctc ccattttccc ttcaaagtag aatgtcttgt   2700

aaagacacag taactcctgt gtgttttgat tagtgagatg ttaccactta ccccttctgc   2760

tgcgcagaat aatattaaga attgctatgc ttatgattca ggctggacag cctggacatt   2820

ttgagcagcg cgagagtaga agtgaatacc cccaggaact ccaattgtgc tgaagctgat   2880

ttgtctgttc gtaggatgat gtgcagcctg tcacagtggc agccacaggc attcagtttg   2940

tgggcatttc ctgtcatttc ggatcctgct atagggaagg ttcagctctc ctgtctgggg   3000

catctactgg agcacctcag aagacaagga ggaaaacact ggctcatgtt ttctttccat   3060

gtgagggagg ggaggtttct agatgatact aaaagcctgt tgccactgtt gtgtcatgat   3120

ttccattctt catcatggaa agccacaagc ctcagaaggc agccagagga caggaagagt   3180

ctgtgatgct catgtctgtg tcatggcatg agggggaatt gacgagtgct tgcttagcat   3240

cagctctcat tgtattgaag gctgtgccct tggtgtgctt agcagtgagc agcgtcttca   3300

ttaggtagct ctggctgggc tttgtcagcc agcgtgtgag aaaggagaac caaaaccaat   3360

acctccttat agaagccaga aggatcacat tggatgagag aaggtgtcta taactgggtt   3420

cttcccaatc ccagctcttt cattaactaa atatgatctt ggacatatct cttaacctcc   3480

atcggcctta gtttttgcat ccaaaaagaa gtgattgggc tggtcttgga aggttttttt   3540

cttttttttc ccctgtgtaa cattcttcat tgttcatcaa catttaagaa atttaatttt   3600

gtagatgttt ttactaaaga gggtaacaaa ctattttgga actgctgtat gttattcaag   3660

ggaagcacgc tgtttggagg aaggagcata cttaatgggt agtattgagg atgaaaggga   3720

atttctctct ctgccatttt atttgataat attaaagaaa taaagactgg aaagggggat   3780

tccttgttaa aggtcagatt ttaaattgca tataaaatga agtgagttgt gtttttttga   3840

accctcaaaa gaaagcctga gaggtgattt atgcctctgg caaggtatta tcatgataac   3900

ttcagttctt ctccataaat gccttcagca aatacccagt gcttatgtgc tgtgtgtatg   3960

tcttaaacct taactttcat gaaatctcat tccatcttag ttcttcatca agtccataga   4020

taaaatcctc tctaagcgtt tctgaagtat gtatccctga acaaatttag tgaaataaaa   4080

tcattaatct gtgttgatcc cattttgcca tacctttcac tttacctcac tgtctccttt   4140

tgtgaaatat tttaagaaag caacgtccct cacaggactg ttttgaggaa tgcctcatgg   4200

ctgtgaagga gtttgtacaa tgcaacattt tgcttagccc ttcagtacat tttacttgga   4260

ttgttttcaa gaactttatt ttttttgaga agaagtcttg ctctatcacc taggctggag   4320

tgcagtggtg cgatctcagc tcactgcaac ctccacc                            4357


<210>  5511
<211>  479
<212>  PRT
<213>  Homo sapiens

<400>  5511

Met Val Arg Ile Gln Arg Arg Lys Leu Leu Ala Ser Cys Leu Cys Val 
1               5                   10                  15


Thr Ala Thr Val Phe Leu Leu Val Thr Leu Gln Val Met Val Glu Leu 
            20                  25                  30


Gly Lys Phe Glu Arg Lys Glu Phe Lys Ser Ser Ser Leu Gln Asp Gly 
        35                  40                  45


His Thr Lys Met Glu Glu Ala Pro Thr His Leu Asn Ser Phe Leu Lys 
    50                  55                  60


Lys Glu Gly Leu Thr Phe Asn Arg Lys Arg Lys Trp Glu Leu Asp Ser 
65                  70                  75                  80


Tyr Pro Ile Met Leu Trp Trp Ser Pro Leu Thr Gly Glu Thr Gly Arg 
                85                  90                  95


Leu Gly Gln Cys Gly Ala Asp Ala Cys Phe Phe Thr Ile Asn Arg Thr 
            100                 105                 110


Tyr Leu His His His Met Thr Lys Ala Phe Leu Phe Tyr Gly Thr Asp 
        115                 120                 125


Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala His His Asp Trp 
    130                 135                 140


Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr Lys Leu Phe His 
145                 150                 155                 160


Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr Phe Ser Arg His 
                165                 170                 175


Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser Ile Glu Val Leu 
            180                 185                 190


Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys Asn Lys Leu Arg 
        195                 200                 205


Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp Cys Asp Pro Pro 
    210                 215                 220


Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr Tyr Ile Glu Val 
225                 230                 235                 240


Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu Pro Gln Gln Leu 
                245                 250                 255


Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr Arg Ile Ile Ala 
            260                 265                 270


Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val Cys Asp Asp Tyr 
        275                 280                 285


Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly Val Val Pro Val 
    290                 295                 300


Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro Ser Asn Lys Ser 
305                 310                 315                 320


Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu Leu Ala Ser Tyr 
                325                 330                 335


Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu Ala Tyr Val Glu 
            340                 345                 350


Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu Leu Thr Ala Leu 
        355                 360                 365


Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln Asp Asn Tyr Ile 
    370                 375                 380


Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp Ala Asn Ile Arg 
385                 390                 395                 400


Leu Gln Glu Lys Gly Leu Pro Pro Lys Arg Trp Glu Ala Glu Asp Thr 
                405                 410                 415


His Leu Ser Cys Pro Glu Pro Thr Val Phe Ala Phe Ser Pro Leu Arg 
            420                 425                 430


Thr Pro Pro Leu Ser Ser Leu Arg Glu Met Trp Ile Ser Ser Phe Glu 
        435                 440                 445


Gln Ser Lys Lys Glu Ala Gln Ala Leu Arg Trp Leu Val Asp Arg Asn 
    450                 455                 460


Gln Asn Phe Ser Ser Gln Glu Phe Trp Gly Leu Val Phe Lys Asp 
465                 470                 475


<210>  5512
<211>  2561
<212>  DNA
<213>  Homo sapiens

<400>  5512
cctagtccag ttggagaagc ggagagtttc ccctgtctta aagaagaggg cccccgcagc     60

cttcccgaga actttccata gggccgtggc ctcaggcgga ctgcgaacca agatcatcag    120

cagggggcgg cccggtgttc ttagaacccg ggtcccaaga gcttgtgaac agggcacgag    180

tgaaaacccg gatccaggct ggctccgccg gaacgcgccc cgagctcgcc cgcgcggccg    240

cctcttccgc tcctgatcgg ctcttcgggt cttcccggcg cccaggcttg ggctcatagg    300

gagaaaggaa gctgcgctgc attctgcggg acgaaccctg ctccgcgcga gaattttttt    360

gattccttct tatttggaga aatctccagc tgctctgatg atagcctaag aagactgcat    420

gctgcttcct ctcgatgcca agccagaccc tctcacaacc tcggatctca gtccttcatg    480

gagacctggt cccagcagga atggcagtgc aggaaattgg cgcccagatg gttcttccat    540

gtgaagttgt ctcgggctct gggctgacga gagaacacct ggtaaccagg ttagccctct    600

gtcagtcacc cagggcaggg cagcatggtg cggattcaga ggaggaagct tttggcatct    660

tgcctgtgcg tcacagccac cgtctttctg cttgtcacac tccaggtcat ggttgagctg    720

gggaagtttg aaaggaagga gtttaaaagt tccagtttgc aagatggaca tacaaaaatg    780

gaggaagcac ctacgcatct taattcattt cttaagaaag aaggattgac cttcaacagg    840

aaaagaaaat gggaattgga cagctacccc attatgctct ggtggtcccc gctgacgggg    900

gagactggga ggttaggcca atgtggagca gatgcttgtt tcttcaccat caaccggacc    960

tacctccatc atcacatgac caaagcattc ctcttctatg gtactgactt taacatagat   1020

agcttacctc tgcctcggaa agcccatcat gactgggctg tttttcatga agagtccccg   1080

aaaaacaatt ataagctctt tcataaacca gtgatcacct tgttcaacta cactgccacg   1140

ttcagcaggc attcccactt gccactaact acccaatact tggagagcat tgaagtcctg   1200

aagtcactcc gatacctagt tcctttgcag tccaaaaaca agcttagaaa aagacttgct   1260

ccgctggtgt atgtacagtc agactgtgac ccaccatcag acagggacag ctatgttcgc   1320

gagctgatga cttacatcga ggtcgattcc tatggtgaat gtttacgaaa caaagacctc   1380

cctcagcagc tgaaaaatcc agcctctatg gatgccgatg gcttttatag gatcattgca   1440

cagtataagt ttatcctagc ttttgagaat gcagtttgtg atgactacat cactgagaag   1500

ttctggaggc cactgaaact gggggtagtc cctgtatatt acggatcccc cagcatcaca   1560

gactggcttc caagtaacaa aagtgctatt cttgtatcag aattttctca ccccagggaa   1620

ctggcaagtt acatcagacg actggattct gatgacagat tgtatgaggc ctatgtagaa   1680

tggaagctga agggtgagat ctctaaccag cgacttctga cagctctcag ggaacggaaa   1740

tggggagtgc aagacgtcaa ccaggacaat tacatcgatg catttgagtg tatggtgtgc   1800

accaaggtgt gggctaatat caggcttcag gaaaagggct taccacccaa aagatgggag   1860

gcagaagata cccacctgag ttgcccagag cccacagtgt ttgctttctc accactccgg   1920

actccacctt tgagctcttt gcgagagatg tggatttcca gctttgaaca atccaagaaa   1980

gaagcccagg cactaaggtg gctggttgat aggaatcaaa acttttcatc tcaagagttt   2040

tggggcctag tattcaagga ctgatttcaa aaatgatcag aatgaaacag actagagcct   2100

tcttgaggtt tattttctag gttgccttaa tatttgaaca taatagctat tctgttgact   2160

atccatcagg ataataatta gttgctgcag tactcataat gagccctttc aaggaataga   2220

tgtaaattac ccttaggggt agccactata ttttttatac taaaaaagga aatatttctt   2280

atggacactg gttatcttcc atgtccgtgt ctgtggaccc acatacttac tgccttttgt   2340

ggaaattcac ctagagtgag tactttcctt gtgcaatgga gggagacgat ctagctatag   2400

attcttgata ctcacctcac tctcaacagc ttattggtat ttggcaaacc tggtatcctg   2460

cagccgagca tgaacatgaa atacattaga acttggcaat gagagatccc atctgttggt   2520

ttccagggat gtaagtgagt aataaaagct gtttcaagtt t                       2561


<210>  5513
<211>  479
<212>  PRT
<213>  Homo sapiens

<400>  5513

Met Val Arg Ile Gln Arg Arg Lys Leu Leu Ala Ser Cys Leu Cys Val 
1               5                   10                  15


Thr Ala Thr Val Phe Leu Leu Val Thr Leu Gln Val Met Val Glu Leu 
            20                  25                  30


Gly Lys Phe Glu Arg Lys Glu Phe Lys Ser Ser Ser Leu Gln Asp Gly 
        35                  40                  45


His Thr Lys Met Glu Glu Ala Pro Thr His Leu Asn Ser Phe Leu Lys 
    50                  55                  60


Lys Glu Gly Leu Thr Phe Asn Arg Lys Arg Lys Trp Glu Leu Asp Ser 
65                  70                  75                  80


Tyr Pro Ile Met Leu Trp Trp Ser Pro Leu Thr Gly Glu Thr Gly Arg 
                85                  90                  95


Leu Gly Gln Cys Gly Ala Asp Ala Cys Phe Phe Thr Ile Asn Arg Thr 
            100                 105                 110


Tyr Leu His His His Met Thr Lys Ala Phe Leu Phe Tyr Gly Thr Asp 
        115                 120                 125


Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala His His Asp Trp 
    130                 135                 140


Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr Lys Leu Phe His 
145                 150                 155                 160


Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr Phe Ser Arg His 
                165                 170                 175


Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser Ile Glu Val Leu 
            180                 185                 190


Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys Asn Lys Leu Arg 
        195                 200                 205


Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp Cys Asp Pro Pro 
    210                 215                 220


Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr Tyr Ile Glu Val 
225                 230                 235                 240


Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu Pro Gln Gln Leu 
                245                 250                 255


Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr Arg Ile Ile Ala 
            260                 265                 270


Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val Cys Asp Asp Tyr 
        275                 280                 285


Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly Val Val Pro Val 
    290                 295                 300


Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro Ser Asn Lys Ser 
305                 310                 315                 320


Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu Leu Ala Ser Tyr 
                325                 330                 335


Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu Ala Tyr Val Glu 
            340                 345                 350


Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu Leu Thr Ala Leu 
        355                 360                 365


Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln Asp Asn Tyr Ile 
    370                 375                 380


Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp Ala Asn Ile Arg 
385                 390                 395                 400


Leu Gln Glu Lys Gly Leu Pro Pro Lys Arg Trp Glu Ala Glu Asp Thr 
                405                 410                 415


His Leu Ser Cys Pro Glu Pro Thr Val Phe Ala Phe Ser Pro Leu Arg 
            420                 425                 430


Thr Pro Pro Leu Ser Ser Leu Arg Glu Met Trp Ile Ser Ser Phe Glu 
        435                 440                 445


Gln Ser Lys Lys Glu Ala Gln Ala Leu Arg Trp Leu Val Asp Arg Asn 
    450                 455                 460


Gln Asn Phe Ser Ser Gln Glu Phe Trp Gly Leu Val Phe Lys Asp 
465                 470                 475


<210>  5514
<211>  2504
<212>  DNA
<213>  Homo sapiens

<400>  5514
cctagtccag ttggagaagc ggagagtttc ccctgtctta aagaagaggg cccccgcagc     60

cttcccgaga actttccata gggccgtggc ctcaggcgga ctgcgaacca agatcatcag    120

cagggggcgg cccggtgttc ttagaacccg ggtcccaaga gcttgtgaac agggcacgag    180

tgaaaacccg gatccaggct ggctccgccg gaacgcgccc cgagctcgcc cgcgcggccg    240

cctcttccgc tcctgatcgg ctcttcgggt cttcccggcg cccaggcttg ggctcatagg    300

gagaaaggaa gctgcgctgc attctgcggg acgaaccctg ctccgcgcga gaattttttt    360

gattccttct tatttggaga aatctccagc tgctctgatg atagcctaag aagactgcat    420

gctgcttcct ctcgatgcca agccagaccc tctcacaacc tcggatctca gtccttcatg    480

gagacctggt cccagcagga atggcagtgc aggaaattgg cgcccagatg gttcttccat    540

gtgaagttgt ctcgggctct gggctgacga gagaacacct ggtaaccagg ttagccctct    600

gtcagtcacc cagggcaggg cagcatggtg cggattcaga ggaggaagct tttggcatct    660

tgcctgtgcg tcacagccac cgtctttctg cttgtcacac tccaggtgaa actgaggttt    720

agtgaatgga cgtgtcaggc agaaacaaag tcattgaaat agaaggtcat ggttgagctg    780

gggaagtttg aaaggaagga gtttaaaagt tccagtttgc aagatggaca tacaaaaatg    840

gaggaagcac ctacgcatct taattcattt cttaagaaag aaggattgac cttcaacagg    900

aaaagaaaat gggaattgga cagctacccc attatgctct ggtggtcccc gctgacgggg    960

gagactggga ggttaggcca atgtggagca gatgcttgtt tcttcaccat caaccggacc   1020

tacctccatc atcacatgac caaagcattc ctcttctatg gtactgactt taacatagat   1080

agcttacctc tgcctcggaa agcccatcat gactgggctg tttttcatga agagtccccg   1140

aaaaacaatt ataagctctt tcataaacca gtgatcacct tgttcaacta cactgccacg   1200

ttcagcaggc attcccactt gccactaact acccaatact tggagagcat tgaagtcctg   1260

aagtcactcc gatacctagt tcctttgcag tccaaaaaca agcttagaaa aagacttgct   1320

ccgctggtgt atgtacagtc agactgtgac ccaccatcag acagggacag ctatgttcgc   1380

gagctgatga cttacatcga ggtcgattcc tatggtgaat gtttacgaaa caaagacctc   1440

cctcagcagc tgaaaaatcc agcctctatg gatgccgatg gcttttatag gatcattgca   1500

cagtataagt ttatcctagc ttttgagaat gcagtttgtg atgactacat cactgagaag   1560

ttctggaggc cactgaaact gggggtagtc cctgtatatt acggatcccc cagcatcaca   1620

gactggcttc caagtaacaa aagtgctatt cttgtatcag aattttctca ccccagggaa   1680

ctggcaagtt acatcagacg actggattct gatgacagat tgtatgaggc ctatgtagaa   1740

tggaagctga agggtgagat ctctaaccag cgacttctga cagctctcag ggaacggaaa   1800

tggggagtgc aagacgtcaa ccaggacaat tacatcgatg catttgagtg tatggtgtgc   1860

accaaggtgt gggctaatat caggcttcag gaaaaggtaa gcaaatcaaa ggtgggcata   1920

gagccagcag gctggccatc ttgatgttct ctgctctcct gcatttcctt ctgttgttgc   1980

cacctcatca gtgttcttca ttcctatcag aaagaccggg ctttgcagga aggttgaata   2040

ttccattact accttttggg actgtcgtaa agtttacaag ccctggacag gccttcattc   2100

ctgaaagcct tcattctcct ttattgtttc ttctggggga tcccgtgctg caggtgctgg   2160

gcagtgacac agaaaactgc agaaaagggg aagagtccct aacataaaaa attaagagtt   2220

cttgccacac atgatggctc acgcctgtaa ttggagcact ttgggaggtt gaggtgggtg   2280

gatcacttga gcccaggggt tcgagaccag cctgggcaac atggcaaaac cccatctcta   2340

ctaaaaatat aaaaattagc ccggcatggt gacatgcact tgtaatccca gctactcgag   2400

aggctgaagt gggagaattg ctggaatcca ggatgcagag gttgcagtga gccgagatca   2460

tgccacaata ctacagcctg ggcgacagag cgagactctg tctc                    2504


<210>  5515
<211>  391
<212>  PRT
<213>  Homo sapiens

<400>  5515

Met Val Glu Leu Gly Lys Phe Glu Arg Lys Glu Phe Lys Ser Ser Ser 
1               5                   10                  15


Leu Gln Asp Gly His Thr Lys Met Glu Glu Ala Pro Thr His Leu Asn 
            20                  25                  30


Ser Phe Leu Lys Lys Glu Gly Leu Thr Phe Asn Arg Lys Arg Lys Trp 
        35                  40                  45


Glu Leu Asp Ser Tyr Pro Ile Met Leu Trp Trp Ser Pro Leu Thr Gly 
    50                  55                  60


Glu Thr Gly Arg Leu Gly Gln Cys Gly Ala Asp Ala Cys Phe Phe Thr 
65                  70                  75                  80


Ile Asn Arg Thr Tyr Leu His His His Met Thr Lys Ala Phe Leu Phe 
                85                  90                  95


Tyr Gly Thr Asp Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala 
            100                 105                 110


His His Asp Trp Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr 
        115                 120                 125


Lys Leu Phe His Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr 
    130                 135                 140


Phe Ser Arg His Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser 
145                 150                 155                 160


Ile Glu Val Leu Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys 
                165                 170                 175


Asn Lys Leu Arg Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp 
            180                 185                 190


Cys Asp Pro Pro Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr 
        195                 200                 205


Tyr Ile Glu Val Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu 
    210                 215                 220


Pro Gln Gln Leu Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr 
225                 230                 235                 240


Arg Ile Ile Ala Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val 
                245                 250                 255


Cys Asp Asp Tyr Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly 
            260                 265                 270


Val Val Pro Val Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro 
        275                 280                 285


Ser Asn Lys Ser Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu 
    290                 295                 300


Leu Ala Ser Tyr Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu 
305                 310                 315                 320


Ala Tyr Val Glu Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu 
                325                 330                 335


Leu Thr Ala Leu Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln 
            340                 345                 350


Asp Asn Tyr Ile Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp 
        355                 360                 365


Ala Asn Ile Arg Leu Gln Glu Lys Val Ser Lys Ser Lys Val Gly Ile 
    370                 375                 380


Glu Pro Ala Gly Trp Pro Ser 
385                 390


<210>  5516
<211>  2482
<212>  DNA
<213>  Homo sapiens

<400>  5516
cctagtccag ttggagaagc ggagagtttc ccctgtctta aagaagaggg cccccgcagc     60

cttcccgaga actttccata gggccgtggc ctcaggcgga ctgcgaacca agatcatcag    120

cagggggcgg cccggtgttc ttagaacccg ggtcccaaga gcttgtgaac agggcacgag    180

tgaaaacccg gatccaggct ggctccgccg gaacgcgccc cgagctcgcc cgcgcggccg    240

cctcttccgc tcctgatcgg ctcttcgggt cttcccggcg cccaggcttg ggctcatagg    300

gagaaaggaa gctgcgctgc attctgcggg acgaaccctg ctccgcgcga gaattttttt    360

gattccttct tatttggaga aatctccagc tgctctgatg atagcctaag aagactgcat    420

gctgcttcct ctcgatgcca agccagaccc tctcacaacc tcggatctca gtccttcatg    480

gagacctggt cccagcagga atggcagtgc aggaaattgg cgcccagatg gttcttccat    540

gtgaagttgt ctcgggctct gggctgacga gagaacacct ggtaaccagg ttagccctct    600

gtcagtcacc cagggcaggg cagcatggtg cggattcaga ggaggaagct tttggcatct    660

tgcctgtgcg tcacagccac cgtctttctg cttgtcacac tccaggtcat ggttgagctg    720

gggaagtttg aaaggaagga gtttaaaagt tccagtttgc aagatggaca tacaaaaatg    780

gaggaagcac ctacgcatct taattcattt cttaagaaag aaggattgac cttcaacagg    840

aaaagaaaat gggaattgga cagctacccc attatgctct ggtggtcccc gctgacgggg    900

gagactggga ggttaggcca atgtggagca gatgcttgtt tcttcaccat caaccggacc    960

tacctccatc atcacatgac caaagcattc ctcttctatg gtcccaagaa gaatcaccac   1020

ctttggcaga aaatgatggt actgacttta acatagatag cttacctctg cctcggaaag   1080

cccatcatga ctgggctgtt tttcatgaag agtccccgaa aaacaattat aagctctttc   1140

ataaaccagt gatcaccttg ttcaactaca ctgccacgtt cagcaggcat tcccacttgc   1200

cactaactac ccaatacttg gagagcattg aagtcctgaa gtcactccga tacctagttc   1260

ctttgcagtc caaaaacaag cttagaaaaa gacttgctcc gctggtgtat gtacagtcag   1320

actgtgaccc accatcagac agggacagct atgttcgcga gctgatgact tacatcgagg   1380

tcgattccta tggtgaatgt ttacgaaaca aagacctccc tcagcagctg aaaaatccag   1440

cctctatgga tgccgatggc ttttatagga tcattgcaca gtataagttt atcctagctt   1500

ttgagaatgc agtttgtgat gactacatca ctgagaagtt ctggaggcca ctgaaactgg   1560

gggtagtccc tgtatattac ggatccccca gcatcacaga ctggcttcca agtaacaaaa   1620

gtgctattct tgtatcagaa ttttctcacc ccagggaact ggcaagttac atcagacgac   1680

tggattctga tgacagattg tatgaggcct atgtagaatg gaagctgaag ggtgagatct   1740

ctaaccagcg acttctgaca gctctcaggg aacggaaatg gggagtgcaa gacgtcaacc   1800

aggacaatta catcgatgca tttgagtgta tggtgtgcac caaggtgtgg gctaatatca   1860

ggcttcagga aaaggtaagc aaatcaaagg tgggcataga gccagcaggc tggccatctt   1920

gatgttctct gctctcctgc atttccttct gttgttgcca cctcatcagt gttcttcatt   1980

cctatcagaa agaccgggct ttgcaggaag gttgaatatt ccattactac cttttgggac   2040

tgtcgtaaag tttacaagcc ctggacaggc cttcattcct gaaagccttc attctccttt   2100

attgtttctt ctgggggatc ccgtgctgca ggtgctgggc agtgacacag aaaactgcag   2160

aaaaggggaa gagtccctaa cataaaaaat taagagttct tgccacacat gatggctcac   2220

gcctgtaatt ggagcacttt gggaggttga ggtgggtgga tcacttgagc ccaggggttc   2280

gagaccagcc tgggcaacat ggcaaaaccc catctctact aaaaatataa aaattagccc   2340

ggcatggtga catgcacttg taatcccagc tactcgagag gctgaagtgg gagaattgct   2400

ggaatccagg atgcagaggt tgcagtgagc cgagatcatg ccacaatact acagcctggg   2460

cgacagagcg agactctgtc tc                                            2482


<210>  5517
<211>  357
<212>  PRT
<213>  Homo sapiens

<400>  5517

Met Gly Ile Gly Gln Leu Pro His Tyr Ala Leu Val Val Pro Ala Asp 
1               5                   10                  15


Gly Gly Asp Trp Glu Val Arg Pro Met Trp Ser Arg Cys Leu Phe Leu 
            20                  25                  30


His His Gln Pro Asp Leu Pro Pro Ser Ser His Asp Gln Ser Ile Pro 
        35                  40                  45


Leu Leu Trp Ser Gln Glu Glu Ser Pro Pro Leu Ala Glu Asn Asp Gly 
    50                  55                  60


Thr Asp Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala His His 
65                  70                  75                  80


Asp Trp Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr Lys Leu 
                85                  90                  95


Phe His Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr Phe Ser 
            100                 105                 110


Arg His Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser Ile Glu 
        115                 120                 125


Val Leu Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys Asn Lys 
    130                 135                 140


Leu Arg Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp Cys Asp 
145                 150                 155                 160


Pro Pro Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr Tyr Ile 
                165                 170                 175


Glu Val Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu Pro Gln 
            180                 185                 190


Gln Leu Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr Arg Ile 
        195                 200                 205


Ile Ala Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val Cys Asp 
    210                 215                 220


Asp Tyr Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly Val Val 
225                 230                 235                 240


Pro Val Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro Ser Asn 
                245                 250                 255


Lys Ser Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu Leu Ala 
            260                 265                 270


Ser Tyr Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu Ala Tyr 
        275                 280                 285


Val Glu Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu Leu Thr 
    290                 295                 300


Ala Leu Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln Asp Asn 
305                 310                 315                 320


Tyr Ile Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp Ala Asn 
                325                 330                 335


Ile Arg Leu Gln Glu Lys Val Ser Lys Ser Lys Val Gly Ile Glu Pro 
            340                 345                 350


Ala Gly Trp Pro Ser 
        355


<210>  5518
<211>  2444
<212>  DNA
<213>  Homo sapiens

<400>  5518
cctagtccag ttggagaagc ggagagtttc ccctgtctta aagaagaggg cccccgcagc     60

cttcccgaga actttccata gggccgtggc ctcaggcgga ctgcgaacca agatcatcag    120

cagggggcgg cccggtgttc ttagaacccg ggtcccaaga gcttgtgaac agggcacgag    180

tgaaaacccg gatccaggct ggctccgccg gaacgcgccc cgagctcgcc cgcgcggccg    240

cctcttccgc tcctgatcgg ctcttcgggt cttcccggcg cccaggcttg ggctcatagg    300

gagaaaggaa gctgcgctgc attctgcggg acgaaccctg ctccgcgcga gaattttttt    360

gattccttct tatttggaga aatctccagc tgctctgatg atagcctaag aagactgcat    420

gctgcttcct ctcgatgcca agccagaccc tctcacaacc tcggatctca gtccttcatg    480

gagacctggt cccagcagga atggcagtgc aggaaattgg cgcccagatg gttcttccat    540

gtgaagttgt ctcgggctct gggctgacga gagaacacct ggtaaccagg ttagccctct    600

gtcagtcacc cagggcaggg cagcatggtg cggattcaga ggaggaagct tttggcatct    660

tgcctgtgcg tcacagccac cgtctttctg cttgtcacac tccaggtcat ggttgagctg    720

gggaagtttg aaaggaagga gtttaaaagt tccagtttgc aagatggaca tacaaaaatg    780

gaggaagcac ctacgcatct taattcattt cttaagaaag aaggattgac cttcaacagg    840

aaaagaaaat gggaattgga cagctacccc attatgctct ggtggtcccc gctgacgggg    900

gagactggga ggttaggcca atgtggagca gatgcttgtt tcttcaccat caaccggacc    960

tacctccatc atcacatgac caaagcattc ctcttctatg gtactgactt taacatagat   1020

agcttacctc tgcctcggaa agcccatcat gactgggctg tttttcatga agagtccccg   1080

aaaaacaatt ataagctctt tcataaacca gtgatcacct tgttcaacta cactgccacg   1140

ttcagcaggc attcccactt gccactaact acccaatact tggagagcat tgaagtcctg   1200

aagtcactcc gatacctagt tcctttgcag tccaaaaaca agcttagaaa aagacttgct   1260

ccgctggtgt atgtacagtc agactgtgac ccaccatcag acagggacag ctatgttcgc   1320

gagctgatga cttacatcga ggtcgattcc tatggtgaat gtttacgaaa caaagacctc   1380

cctcagcagc tgaaaaatcc agcctctatg gatgccgatg gcttttatag gatcattgca   1440

cagtataagt ttatcctagc ttttgagaat gcagtttgtg atgactacat cactgagaag   1500

ttctggaggc cactgaaact gggggtagtc cctgtatatt acggatcccc cagcatcaca   1560

gactggcttc caagtaacaa aagtgctatt cttgtatcag aattttctca ccccagggaa   1620

ctggcaagtt acatcagacg actggattct gatgacagat tgtatgaggc ctatgtagaa   1680

tggaagctga agggtgagat ctctaaccag cgacttctga cagctctcag ggaacggaaa   1740

tggggagtgc aagacgtcaa ccaggacaat tacatcgatg catttgagtg tatggtgtgc   1800

accaaggtgt gggctaatat caggcttcag gaaaaggtaa gcaaatcaaa ggtgggcata   1860

gagccagcag gctggccatc ttgatgttct ctgctctcct gcatttcctt ctgttgttgc   1920

cacctcatca gtgttcttca ttcctatcag aaagaccggg ctttgcagga aggttgaata   1980

ttccattact accttttggg actgtcgtaa agtttacaag ccctggacag gccttcattc   2040

ctgaaagcct tcattctcct ttattgtttc ttctggggga tcccgtgctg caggtgctgg   2100

gcagtgacac agaaaactgc agaaaagggg aagagtccct aacataaaaa attaagagtt   2160

cttgccacac atgatggctc acgcctgtaa ttggagcact ttgggaggtt gaggtgggtg   2220

gatcacttga gcccaggggt tcgagaccag cctgggcaac atggcaaaac cccatctcta   2280

ctaaaaatat aaaaattagc ccggcatggt gacatgcact tgtaatccca gctactcgag   2340

aggctgaagt gggagaattg ctggaatcca ggatgcagag gttgcagtga gccgagatca   2400

tgccacaata ctacagcctg ggcgacagag cgagactctg tctc                    2444


<210>  5519
<211>  419
<212>  PRT
<213>  Homo sapiens

<400>  5519

Met Val Arg Ile Gln Arg Arg Lys Leu Leu Ala Ser Cys Leu Cys Val 
1               5                   10                  15


Thr Ala Thr Val Phe Leu Leu Val Thr Leu Gln Val Met Val Glu Leu 
            20                  25                  30


Gly Lys Phe Glu Arg Lys Glu Phe Lys Ser Ser Ser Leu Gln Asp Gly 
        35                  40                  45


His Thr Lys Met Glu Glu Ala Pro Thr His Leu Asn Ser Phe Leu Lys 
    50                  55                  60


Lys Glu Gly Leu Thr Phe Asn Arg Lys Arg Lys Trp Glu Leu Asp Ser 
65                  70                  75                  80


Tyr Pro Ile Met Leu Trp Trp Ser Pro Leu Thr Gly Glu Thr Gly Arg 
                85                  90                  95


Leu Gly Gln Cys Gly Ala Asp Ala Cys Phe Phe Thr Ile Asn Arg Thr 
            100                 105                 110


Tyr Leu His His His Met Thr Lys Ala Phe Leu Phe Tyr Gly Thr Asp 
        115                 120                 125


Phe Asn Ile Asp Ser Leu Pro Leu Pro Arg Lys Ala His His Asp Trp 
    130                 135                 140


Ala Val Phe His Glu Glu Ser Pro Lys Asn Asn Tyr Lys Leu Phe His 
145                 150                 155                 160


Lys Pro Val Ile Thr Leu Phe Asn Tyr Thr Ala Thr Phe Ser Arg His 
                165                 170                 175


Ser His Leu Pro Leu Thr Thr Gln Tyr Leu Glu Ser Ile Glu Val Leu 
            180                 185                 190


Lys Ser Leu Arg Tyr Leu Val Pro Leu Gln Ser Lys Asn Lys Leu Arg 
        195                 200                 205


Lys Arg Leu Ala Pro Leu Val Tyr Val Gln Ser Asp Cys Asp Pro Pro 
    210                 215                 220


Ser Asp Arg Asp Ser Tyr Val Arg Glu Leu Met Thr Tyr Ile Glu Val 
225                 230                 235                 240


Asp Ser Tyr Gly Glu Cys Leu Arg Asn Lys Asp Leu Pro Gln Gln Leu 
                245                 250                 255


Lys Asn Pro Ala Ser Met Asp Ala Asp Gly Phe Tyr Arg Ile Ile Ala 
            260                 265                 270


Gln Tyr Lys Phe Ile Leu Ala Phe Glu Asn Ala Val Cys Asp Asp Tyr 
        275                 280                 285


Ile Thr Glu Lys Phe Trp Arg Pro Leu Lys Leu Gly Val Val Pro Val 
    290                 295                 300


Tyr Tyr Gly Ser Pro Ser Ile Thr Asp Trp Leu Pro Ser Asn Lys Ser 
305                 310                 315                 320


Ala Ile Leu Val Ser Glu Phe Ser His Pro Arg Glu Leu Ala Ser Tyr 
                325                 330                 335


Ile Arg Arg Leu Asp Ser Asp Asp Arg Leu Tyr Glu Ala Tyr Val Glu 
            340                 345                 350


Trp Lys Leu Lys Gly Glu Ile Ser Asn Gln Arg Leu Leu Thr Ala Leu 
        355                 360                 365


Arg Glu Arg Lys Trp Gly Val Gln Asp Val Asn Gln Asp Asn Tyr Ile 
    370                 375                 380


Asp Ala Phe Glu Cys Met Val Cys Thr Lys Val Trp Ala Asn Ile Arg 
385                 390                 395                 400


Leu Gln Glu Lys Val Ser Lys Ser Lys Val Gly Ile Glu Pro Ala Gly 
                405                 410                 415


Trp Pro Ser 



<210>  5520
<211>  1179
<212>  DNA
<213>  Homo sapiens

<400>  5520
gtggcctgcg tttgtaatcc cagctactcc agaggctgag gcaggagaat cacttgaact     60

cgggaagagg aggctgcagt aggctgagat cacgccattg cactctagcc tgggcgacag    120

agagagactc tgtctcaaaa aataaaaaaa taaaaaataa ataaaaaaat aagttgtatg    180

gcagaagaag aatctctcct taaaagcatc cctattattt ggaaatgaat ttataactca    240

catagtagat attgatctga aatgtggaat aaattttacc tttggagttg tatcctatgg    300

ctttctaaaa gcctttcttt taagtgactg gttgtacatt tgcaggggaa gaaggtcaga    360

tgaaaagata gtttgtggct acaagtcatc tcccatggat caaactactg gggagagcca    420

cattgttcca tcataaaaat gctgagagag ctattggcaa caggcagact ttagttttca    480

gtgatggctc tgctgctcta gtgttgactt tggcgtctca ggtgatccat gactttttaa    540

agccaatata atttcttact ccttctggag tgctgcttgg ctttcactca gtggtttttt    600

ttttttttct tttttggcct tggataccgt tgagaatcta atgaaagtca cgggccctcc    660

ccagggagtt acagactcca tgcaatgctt caatgatcag cggcctttat ctaacaccag    720

gagcagcgag cacataaaag aggtcatggt tgagctgggg aagtttgaaa ggaaggagtt    780

taaaagttcc agtttgcaag atggacatac aaaaatggag gaagcaccta cgcatcttaa    840

ttcatttctt aagaaagaag gattgacctt caacaggaaa agaaaatggg aattggacag    900

ctaccccatt atgctctggt ggtccccgct gacgggggag actgggaggt taggccaatg    960

tggagcagat gcttgtttct tcaccatcaa ccggacctac ctccatcatc acatgaccaa   1020

agcattcctc ttctatggta agcaggactt tcgcctttct cccttgtttg ctgtggtctt   1080

cctccaaagc tgagttacag tttacctctg aaaagtgatg gtggagctcc ccttgaaaac   1140

actttgacac ccctgatttc ctttgcattt gctctgtgg                          1179


<210>  5521
<211>  150
<212>  PRT
<213>  Homo sapiens

<400>  5521

Met Lys Val Thr Gly Pro Pro Gln Gly Val Thr Asp Ser Met Gln Cys 
1               5                   10                  15


Phe Asn Asp Gln Arg Pro Leu Ser Asn Thr Arg Ser Ser Glu His Ile 
            20                  25                  30


Lys Glu Val Met Val Glu Leu Gly Lys Phe Glu Arg Lys Glu Phe Lys 
        35                  40                  45


Ser Ser Ser Leu Gln Asp Gly His Thr Lys Met Glu Glu Ala Pro Thr 
    50                  55                  60


His Leu Asn Ser Phe Leu Lys Lys Glu Gly Leu Thr Phe Asn Arg Lys 
65                  70                  75                  80


Arg Lys Trp Glu Leu Asp Ser Tyr Pro Ile Met Leu Trp Trp Ser Pro 
                85                  90                  95


Leu Thr Gly Glu Thr Gly Arg Leu Gly Gln Cys Gly Ala Asp Ala Cys 
            100                 105                 110


Phe Phe Thr Ile Asn Arg Thr Tyr Leu His His His Met Thr Lys Ala 
        115                 120                 125


Phe Leu Phe Tyr Gly Lys Gln Asp Phe Arg Leu Ser Pro Leu Phe Ala 
    130                 135                 140


Val Val Phe Leu Gln Ser 
145                 150


<210>  5522
<211>  703
<212>  DNA
<213>  Homo sapiens

<400>  5522
aaggaggaaa gccctcacta ggaagagact tgtgccaccc ggggcaagaa catcagagat     60

ccagtgacag cccagcgacc tccgggatca attgcaatgg gaggtgtgtt ttatggacca    120

tgtgctgcta tgtatgcctg aagaagtact tgaaatgcaa atttggggag actttgccat    180

ataaatgctt ggctggatta agcgcctaat taggatggtt tttcaacaag ttggagtaag    240

catgcaatcg gtactttggt ctaggaagcc atatggttcg tctcgaagta tcgtaaggaa    300

aattggtact aatttgtctc tgattcagtg tccaagagtt cagtttcaga ttaacagcca    360

tgcaacagaa tggagtccca gccacccagg agaggatgca gtggcgtctt ttgctgatgt    420

tggatgggta gccaaagaag aaggagagtg ttcagcaaga ctaaggacag aggtcagatc    480

aaggccaccc cttcaggatg accttctttt ctttgagaag gccccaagca gacagatttc    540

cttaccagac ttgtctcaag aagagcctca gctgaagacc ccagcgctgg caaatgagga    600

agcactgcag aagatttgcg ctctcgaaaa tgaacttgct gctctcagag ctcagattgc    660

caaaattgtg acccagcagg agcagcaaaa tctcactgca ggt                      703


<210>  5523
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  5523

Met Leu Gly Trp Ile Lys Arg Leu Ile Arg Met Val Phe Gln Gln Val 
1               5                   10                  15


Gly Val Ser Met Gln Ser Val Leu Trp Ser Arg Lys Pro Tyr Gly Ser 
            20                  25                  30


Ser Arg Ser Ile Val Arg Lys Ile Gly Thr Asn Leu Ser Leu Ile Gln 
        35                  40                  45


Cys Pro Arg Val Gln Phe Gln Ile Asn Ser His Ala Thr Glu Trp Ser 
    50                  55                  60


Pro Ser His Pro Gly Glu Asp Ala Val Ala Ser Phe Ala Asp Val Gly 
65                  70                  75                  80


Trp Val Ala Lys Glu Glu Gly Glu Cys Ser Ala Arg Leu Arg Thr Glu 
                85                  90                  95


Val Arg Ser Arg Pro Pro Leu Gln Asp Asp Leu Leu Phe Phe Glu Lys 
            100                 105                 110


Ala Pro Ser Arg Gln Ile Ser Leu Pro Asp Leu Ser Gln Glu Glu Pro 
        115                 120                 125


Gln Leu Lys Thr Pro Ala Leu Ala Asn Glu Glu Ala Leu Gln Lys Ile 
    130                 135                 140


Cys Ala Leu Glu Asn Glu Leu Ala Ala Leu Arg Ala Gln Ile Ala Lys 
145                 150                 155                 160


Ile Val Thr Gln Gln Glu Gln Gln Asn Leu Thr Ala 
                165                 170


<210>  5524
<211>  2811
<212>  DNA
<213>  Homo sapiens

<400>  5524
ccgactgtga ctctcagcag ccggcttgcg gagcggttgc cgcgtcctct gccgagcttc     60

ttgtgcccgc ctccgagcct gaggaaacag ctgattgatc agcctggctc aggcttgggg    120

cggggattgg ctgattggca gcaacgccac gggacagcca agctagaagc ctgaggagcc    180

ggagagggtg ctggctgccg cgcggccgag tgtgttttat ggaccatgtg ctgctatgta    240

tgcctgaaga agtacttgaa atgcaaattt ggggagactt tgccatataa atgcttggct    300

ggattaagcg cctaattagg atggtttttc aacaagttgg agtaagcatg caatcggtac    360

tttggtctag gaagccatat ggttcgtctc gaagtatcgt aaggaaaatt ggtactaatt    420

tgtctctgat tcagtgtcca agagttcagt ttcagattaa cagccatgca acagaatgga    480

gtcccagcca cccaggagag gatgcagtgg cgtcttttgc tgatgttgga tgggtagcca    540

aagaagaagg agagtgttca gcaagactaa ggacagaggt cagatcaagg ccaccccttc    600

aggatgacct tcttttcttt gagaaggccc caagcagaca gatttcctta ccagacttgt    660

ctcaagaaga gcctcagctg aagaccccag cgctggcaaa tgaggaagca ctgcagaaga    720

tttgcgctct cgaaaatgaa cttgctgctc tcagagctca gattgccaaa attgtgaccc    780

agcaggagca gcaaaatctc actgcaggtg acttagattc taccacattt ggtaccatac    840

caccacaccc tccacctccc ccaccgcccc tgcctccccc tgcactgggg ctccaccaaa    900

gtacatctgc tgttgatctg attaaagaac gaagagagaa aagagccaat gctggaaaga    960

ctttggttaa gaacaatcca aagaaacctg aaatgccaaa tatgctagag atccttaaag   1020

agatgaacag tgtaaaactt cggtcagtga agaggtcaga gcaagatgtg aagcccaagc   1080

cagtggatgc tactgaccct gctgccctca tagcagaggc tctgaaaaag aaatttgctt   1140

atcggtatcg aagtgatagc caagatgaag ttgaaaaagg aattccaaag tctgaatcag   1200

aggccacctc agagagagtg ttgtttgggc cacacatgtt gaagccaaca ggaaaaatga   1260

aggctttaat tgaaaatgta tcagactcct aatagacaat gagctgcgaa aagactcctg   1320

gttcccctgt tgatttgtga gggccaagtt tgctagtaga aatcgacact gtttagtaaa   1380

tacctcttta gtattcagtg gtcttctttt caggctaatt agtggattaa gcaataatga   1440

aagcactaag tttggttttg cttttgtgag atggtcagct ttggtgctct ccacaacatg   1500

tgtgttctga catgtttcta atatgtggcc agggcgttca gatttccagt tttgaaaaca   1560

attgtataga tttcacaaca caaaaaggac atttgtggat gttactgcac attttaaatt   1620

cttaacacta atttatctgt ataagtgttt tatatgcata tttttggaca taaacagttt   1680

atgtaaaatt agtaatgaat gatggcaacg agggcactgt tatcttcgtt tgttttcaat   1740

gatcatttag cattcaatga tggaacagct ggtataacat aagttgttgg catgaaatat   1800

ttgagattgg aaacttcttg ccttgaacag aacttatatc ttagattctc tctcacattt   1860

tcttggagct ggggtttgaa taggaaccag atgatgttca ctgctgaaat tccataatgc   1920

ttcccattga agggaagttg agaaccagga aagctgcttt cacgtcattg ccatccagta   1980

ctgacaggga agaaagatgt agttttccag tagtgatgaa tcaaattatt gaattaaatt   2040

tcttcttaag aagtaaaaac tcagaatgta ccatcttgtt tcctttcagt ttattaaatg   2100

gcatcataaa gatgactttg ctaagttaat agagttaaaa atttttttaa tataagccaa   2160

aatattaact ttaatgaaac attgacttgg caaatgaatt tcctataaat tatcattggt   2220

cagaatgctg ttttgtttaa taatattacg caacataaac cataggtgtt attagaagtg   2280

gagaactgcc tttttcatct ggggctttta aggacttgct ataaatgatt attttttaaa   2340

tgctttataa atcttcatgg tttttctatt tctgatacac tcagctatag ttaataccag   2400

agtatcctac caggagtaat atttggaata tttaaatcta gtaaaagaag aaagttgtac   2460

ttcctggctg ggagtattag gagatgggag tagagattca cttttaagtt cttgaaaata   2520

tatgcattct cctaaatatt aacaaaaatg atttggggaa atgacatggc ttgattgttc   2580

tgtttaaatt tgtactgtgg cttatgttac acatgttcat gttcacctct cattcacctg   2640

ttttatatgg tttaaaattc tctttaacaa aattcagaaa attcacctga aacgtatttt   2700

gacctaaaag aaacatattt ttgtatcagt attgaatttt ggacagtgcc cccatataag   2760

gaagttactg ttttaaaata aagcaaacta actgttttat tttccttgga c            2811


<210>  5525
<211>  333
<212>  PRT
<213>  Homo sapiens

<400>  5525

Met Leu Gly Trp Ile Lys Arg Leu Ile Arg Met Val Phe Gln Gln Val 
1               5                   10                  15


Gly Val Ser Met Gln Ser Val Leu Trp Ser Arg Lys Pro Tyr Gly Ser 
            20                  25                  30


Ser Arg Ser Ile Val Arg Lys Ile Gly Thr Asn Leu Ser Leu Ile Gln 
        35                  40                  45


Cys Pro Arg Val Gln Phe Gln Ile Asn Ser His Ala Thr Glu Trp Ser 
    50                  55                  60


Pro Ser His Pro Gly Glu Asp Ala Val Ala Ser Phe Ala Asp Val Gly 
65                  70                  75                  80


Trp Val Ala Lys Glu Glu Gly Glu Cys Ser Ala Arg Leu Arg Thr Glu 
                85                  90                  95


Val Arg Ser Arg Pro Pro Leu Gln Asp Asp Leu Leu Phe Phe Glu Lys 
            100                 105                 110


Ala Pro Ser Arg Gln Ile Ser Leu Pro Asp Leu Ser Gln Glu Glu Pro 
        115                 120                 125


Gln Leu Lys Thr Pro Ala Leu Ala Asn Glu Glu Ala Leu Gln Lys Ile 
    130                 135                 140


Cys Ala Leu Glu Asn Glu Leu Ala Ala Leu Arg Ala Gln Ile Ala Lys 
145                 150                 155                 160


Ile Val Thr Gln Gln Glu Gln Gln Asn Leu Thr Ala Gly Asp Leu Asp 
                165                 170                 175


Ser Thr Thr Phe Gly Thr Ile Pro Pro His Pro Pro Pro Pro Pro Pro 
            180                 185                 190


Pro Leu Pro Pro Pro Ala Leu Gly Leu His Gln Ser Thr Ser Ala Val 
        195                 200                 205


Asp Leu Ile Lys Glu Arg Arg Glu Lys Arg Ala Asn Ala Gly Lys Thr 
    210                 215                 220


Leu Val Lys Asn Asn Pro Lys Lys Pro Glu Met Pro Asn Met Leu Glu 
225                 230                 235                 240


Ile Leu Lys Glu Met Asn Ser Val Lys Leu Arg Ser Val Lys Arg Ser 
                245                 250                 255


Glu Gln Asp Val Lys Pro Lys Pro Val Asp Ala Thr Asp Pro Ala Ala 
            260                 265                 270


Leu Ile Ala Glu Ala Leu Lys Lys Lys Phe Ala Tyr Arg Tyr Arg Ser 
        275                 280                 285


Asp Ser Gln Asp Glu Val Glu Lys Gly Ile Pro Lys Ser Glu Ser Glu 
    290                 295                 300


Ala Thr Ser Glu Arg Val Leu Phe Gly Pro His Met Leu Lys Pro Thr 
305                 310                 315                 320


Gly Lys Met Lys Ala Leu Ile Glu Asn Val Ser Asp Ser 
                325                 330


<210>  5526
<211>  765
<212>  DNA
<213>  Homo sapiens

<400>  5526
ctgaggaaac agctgattga tcagcctggc tcaggcttgg ggcggggatt ggctgattgg     60

cagcaacgcc acgggacagc caagctagaa gcctgaggag ccggagaggg tgctggctgc    120

cgcgcggccg agtgtgtttt atggaccatg tgctgctatg tatgcctgaa gaagtacttg    180

aaatgcaaat ttggggagac tttgccatat aaatgcttgg ctggattaag cgcctaatta    240

ggatggtttt tcaacaagtt ggagtaagca tgcaatcggt actttggtct aggaagccat    300

atggttcgtc tcgaagtatc gtaaggaaaa ttggtactaa tttgtctctg attcagtgtc    360

caagagttca gtttcagctg tagtaggaca ggaccttgct gggaaccttc aattaacagc    420

catgcaacag aatggagtcc cagccaccca ggagaggatg cagtggcgtc ttttgctgat    480

gttggatggg tagccaaaga agaaggagag tgttcagcaa gactaaggac agaggtcaga    540

tcaaggccac cccttcagga tgaccttctt ttctttgaga aggccccaag cagacagatt    600

tccttaccag acttgtctca agaagagcct cagctgaaga ccccagcgct ggcaaatgag    660

gaagcactgc agaagatttg cgctctcgaa aatgaacttg ctgctctcag agctcagatt    720

gccaaaattg tgacccagca ggagcagcaa aatctcactg caggt                    765


<210>  5527
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  5527

Met Leu Gly Trp Ile Lys Arg Leu Ile Arg Met Val Phe Gln Gln Val 
1               5                   10                  15


Gly Val Ser Met Gln Ser Val Leu Trp Ser Arg Lys Pro Tyr Gly Ser 
            20                  25                  30


Ser Arg Ser Ile Val Arg Lys Ile Gly Thr Asn Leu Ser Leu Ile Gln 
        35                  40                  45


Cys Pro Arg Val Gln Phe Gln Leu 
    50                  55


<210>  5528
<211>  802
<212>  DNA
<213>  Homo sapiens

<400>  5528
ctgaggaaac agctgattga tcagcctggc tcaggcttgg ggcggggatt ggctgattgg     60

cagcaacgcc acgggacagc caagctagaa gcctgaggag ccggagaggg tgctggctgc    120

cgcgcggccg agtgtgtttt atggaccatg tgctgctatg tatgcctgaa gaagtacttg    180

aaatgcaaat ttggggagac tttgccatat aaatgcttgg ctggattaag cgcctaatta    240

ggatggtttt tcaacaagtt ggagtaagca tgcaatcgaa tagtatgaaa acctgatgaa    300

aataaaattt ttactgtact ttggtctagg aagccatatg gttcgtctcg aagtatcgta    360

aggaaaattg gtactaattt gtctctgatt cagtgtccaa gagttcagtt tcagctgtag    420

taggacagga ccttgctggg aaccttcaat taacagccat gcaacagaat ggagtcccag    480

ccacccagga gaggatgcag tggcgtcttt tgctgatgtt ggatgggtag ccaaagaaga    540

aggagagtgt tcagcaagac taaggacaga ggtcagatca aggccacccc ttcaggatga    600

ccttcttttc tttgagaagg ccccaagcag acagatttcc ttaccagact tgtctcaaga    660

agagcctcag ctgaagaccc cagcgctggc aaatgaggaa gcactgcaga agatttgcgc    720

tctcgaaaat gaacttgctg ctctcagagc tcagattgcc aaaattgtga cccagcagga    780

gcagcaaaat ctcactgcag gt                                             802


<210>  5529
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  5529

Phe Ser Val Gln Glu Phe Ser Phe Ser Cys Ser Arg Thr Gly Pro Cys 
1               5                   10                  15


Trp Glu Pro Ser Ile Asn Ser His Ala Thr Glu Trp Ser Pro Ser His 
            20                  25                  30


Pro Gly Glu Asp Ala Val Ala Ser Phe Ala Asp Val Gly Trp Val Ala 
        35                  40                  45


Lys Glu Glu Gly Glu Cys Ser Ala Arg Leu Arg Thr Glu Val Arg Ser 
    50                  55                  60


Arg Pro Pro Leu Gln Asp Asp Leu Leu Phe Phe Glu Lys Ala Pro Ser 
65                  70                  75                  80


Arg Gln Ile Ser Leu Pro Asp Leu Ser Gln Glu Glu Pro Gln Leu Lys 
                85                  90                  95


Thr Pro Ala Leu Ala Asn Glu Glu Ala Leu Gln Lys Ile Cys Ala Leu 
            100                 105                 110


Glu Asn Glu Leu Ala Ala Leu Arg Ala Gln Ile Ala Lys Ile Val Thr 
        115                 120                 125


Gln Gln Glu Gln Gln Asn Leu Thr Ala 
    130                 135


<210>  5530
<211>  813
<212>  DNA
<213>  Homo sapiens

<400>  5530
ctgaggaaac agctgattga tcagcctggc tcaggcttgg ggcggggatt ggctgattgg     60

cagcaacgcc acgggacagc caagctagaa gcctgaggag ccggagaggg tgctggctgc    120

cgcgcggccg agtgtgtttt atggaccatg tgctgctatg tatgcctgaa gaagtacttg    180

aaatgcaaat ttggggagac tttgccatat aaatgcttgg ctggattaag cgcctaatta    240

ggatggtttt tcaacaagtt ggagtaagca tgcaatcggt actttggtct aggaagccat    300

atggttcgtc tcgaagtatc gtaaggaaaa ttggtactaa tttgtctctg attcagtgtc    360

caagagttca gtttcagatt aacagccatg caacagaatg gagtcccagc cacccaggag    420

aggatgcagt ggcgtctttt gctgatgttg gatgggtagc caaagaagaa ggagagtgtt    480

cagcaagact aaggacagag gtcagatcaa ggccacccct tcaggatgac cttcttttct    540

ttgagaaggc cccaagcaga cagatttcct taccagactt gtctcaagaa gagcctcagc    600

tgaagacccc agcgctggca aatgaggaag cactgcagaa gatttgcgct ctcgaaaatg    660

aacttgctgt tgatctgatt aaagaacgaa gagagaaaag agccaatgct ggaaagactt    720

tggttaagaa caatccaaag aaacctgaaa tgccaaatat gctagagatc cttaaagaga    780

tgaacagtgt aaaacttcgg tcagtgaaga ggt                                 813


<210>  5531
<211>  199
<212>  PRT
<213>  Homo sapiens

<400>  5531

Met Leu Gly Trp Ile Lys Arg Leu Ile Arg Met Val Phe Gln Gln Val 
1               5                   10                  15


Gly Val Ser Met Gln Ser Val Leu Trp Ser Arg Lys Pro Tyr Gly Ser 
            20                  25                  30


Ser Arg Ser Ile Val Arg Lys Ile Gly Thr Asn Leu Ser Leu Ile Gln 
        35                  40                  45


Cys Pro Arg Val Gln Phe Gln Ile Asn Ser His Ala Thr Glu Trp Ser 
    50                  55                  60


Pro Ser His Pro Gly Glu Asp Ala Val Ala Ser Phe Ala Asp Val Gly 
65                  70                  75                  80


Trp Val Ala Lys Glu Glu Gly Glu Cys Ser Ala Arg Leu Arg Thr Glu 
                85                  90                  95


Val Arg Ser Arg Pro Pro Leu Gln Asp Asp Leu Leu Phe Phe Glu Lys 
            100                 105                 110


Ala Pro Ser Arg Gln Ile Ser Leu Pro Asp Leu Ser Gln Glu Glu Pro 
        115                 120                 125


Gln Leu Lys Thr Pro Ala Leu Ala Asn Glu Glu Ala Leu Gln Lys Ile 
    130                 135                 140


Cys Ala Leu Glu Asn Glu Leu Ala Val Asp Leu Ile Lys Glu Arg Arg 
145                 150                 155                 160


Glu Lys Arg Ala Asn Ala Gly Lys Thr Leu Val Lys Asn Asn Pro Lys 
                165                 170                 175


Lys Pro Glu Met Pro Asn Met Leu Glu Ile Leu Lys Glu Met Asn Ser 
            180                 185                 190


Val Lys Leu Arg Ser Val Lys 
        195


<210>  5532
<211>  635
<212>  DNA
<213>  Homo sapiens

<400>  5532
atctcagcta ctcaagaggc tgaagcagga gaatcacttg aacctggagg gggcagaggt     60

tgcagggagc cgagattgct ccacttcact ccagcctggg cgaaagagtg aaactccatc    120

tcaaaaataa atacataata gtaataaggt actttggtct aggaagccat atggttcgtc    180

tcgaagtatc gtaaggaaaa ttggtactaa tttgtctctg attcagtgtc caagagttca    240

gtttcagctg tagtaggaca ggaccttgct gggaaccttc aattaacagc catgcaacag    300

aatggagtcc cagccaccca ggagaggatg cagtggcgtc ttttgctgat gttggatggg    360

tagccaaaga agaaggagag tgttcagcaa gactaaggac agaggtcaga tcaaggccac    420

cccttcagga tgaccttctt ttctttgaga aggccccaag cagacagatt tccttaccag    480

acttgtctca agaagagcct cagctgaaga ccccagcgct ggcaaatgag gaagcactgc    540

agaagatttg cgctctcgaa aatgaacttg ctgctctcag agctcagatt gccaaaattg    600

tgacccagca ggagcagcaa aatctcactg caggt                               635


<210>  5533
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  5533

Phe Ser Val Gln Glu Phe Ser Phe Ser Cys Ser Arg Thr Gly Pro Cys 
1               5                   10                  15


Trp Glu Pro Ser Ile Asn Ser His Ala Thr Glu Trp Ser Pro Ser His 
            20                  25                  30


Pro Gly Glu Asp Ala Val Ala Ser Phe Ala Asp Val Gly Trp Val Ala 
        35                  40                  45


Lys Glu Glu Gly Glu Cys Ser Ala Arg Leu Arg Thr Glu Val Arg Ser 
    50                  55                  60


Arg Pro Pro Leu Gln Asp Asp Leu Leu Phe Phe Glu Lys Ala Pro Ser 
65                  70                  75                  80


Arg Gln Ile Ser Leu Pro Asp Leu Ser Gln Glu Glu Pro Gln Leu Lys 
                85                  90                  95


Thr Pro Ala Leu Ala Asn Glu Glu Ala Leu Gln Lys Ile Cys Ala Leu 
            100                 105                 110


Glu Asn Glu Leu Ala Ala Leu Arg Ala Gln Ile Ala Lys Ile Val Thr 
        115                 120                 125


Gln Gln Glu Gln Gln Asn Leu Thr Ala 
    130                 135


<210>  5534
<211>  978
<212>  DNA
<213>  Homo sapiens

<400>  5534
caggctaatt agtggattaa gcaataatga aagcactaag tttggttttg cttttgtgag     60

atggtcagct ttggtgctct ccacaacatg tgtgttctga catgtttcta atatgtggcc    120

agggcgttca gatttccagt tttgaaaaca attgtataga tttcacaaca caaaaaggac    180

atttgtggat gttactgcac attttaaatt cttaacacta atttatctgt ataagtgttt    240

tatatgcata tttttggaca taaacagttt atgtaaaatt agtaatgaat gatggcaacg    300

agggcactgt tatcttcgtt tgttttcaat gatcatttag cattcaatga tggaacagct    360

ggtataacat aagttgttgg catgaaatat ttgagattgg aaacttcttg ccttgaacag    420

aacttatatc ttagattctc tctcacattt tcttggagct ggggtttgaa taggaaccag    480

atgatgttca ctgctgaaat tccataatgc ttcccattga agggaagttg agaaccagga    540

aagctgcttt cacgtcattg ccatccagta ctgacaggga agaaagatgt agttttccag    600

tagtgatgaa tcaaattatt gaattaaatt tcttcttaag aagtaaaaac tcagaatgta    660

ccatcttgtt tcctttcagt ttattaaatg gcatcataaa gatgactttg ctaagttaat    720

agagttaaaa atttttttaa tataagccaa aatattaact ttaatgaaac attgacttgg    780

caaatgaatt tcctataaat tatcattggt cagaatgctg ttttatatgg tttaaaattc    840

tctttaacaa aattcagaaa attcacctga aacgtatttt gacctaaaag aaacatattt    900

ttgtatcagt attgaatttt ggacagtgcc cccatataag gaagttactg ttttaaaata    960

aagcaaacta actgtttt                                                  978


<210>  5535
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  5535

Met Leu Pro Ile Glu Gly Lys Leu Arg Thr Arg Lys Ala Ala Phe Thr 
1               5                   10                  15


Ser Leu Pro Ser Ser Thr Asp Arg Glu Glu Arg Cys Ser Phe Pro Val 
            20                  25                  30


Val Met Asn Gln Ile Ile Glu Leu Asn Phe Phe Leu Arg Ser Lys Asn 
        35                  40                  45


Ser Glu Cys Thr Ile Leu Phe Pro Phe Ser Leu Leu Asn Gly Ile Ile 
    50                  55                  60


Lys Met Thr Leu Leu Ser 
65                  70


<210>  5536
<211>  1195
<212>  DNA
<213>  Homo sapiens

<400>  5536
aactaggctg gagtgcagtg gcatgatcac tgcagcctcc acctcctagg ctcaagcaat     60

cctcccacct cagcctcctg agtgccacca caccacccag tccagcctag gtgacagagc    120

aagactctgt ctcaaaaaaa aaaaaaaaac ttttttatag agacagggtc tctctttgtt    180

ggcttggctg gtcttgaact cttgggctca agcagtcctg ccaccgtggc ctctcaaagt    240

gctgggatta caggtgtgag acactgcatc aggcctatag ctccacttaa atacgaccta    300

tattactgga atattttttt ctaaaaaatt ttaggaaaca gttaaatatt taaaagatta    360

cttttttaaa aagcaagtaa atattacaga acagaatgca aaatttattt tacatgggag    420

actaaaaatt ttcacacaca tggccaccct ttgggcctct tggctcaaca tttcaggggc    480

tgagggagtc tctgctctag gagtaaaagg tccttggaga gaaaattttg acaagtccta    540

actttaaaaa agaaaaattg gttcctggtc aatatttgta ctcactgtaa atgtgatggt    600

tggtaatgat actctgtata aaagtaaaaa tcatatttta tgtcctttgc aaacaaatat    660

atttgtacct gaggtacaga ttagaggtgc tagtaattcc ttgaagattc tgaaaatgat    720

ctttttttcc aaaatgcttt cttggttttt attaaacttt ctattttctt aaaactctca    780

catcaggtat ttccagtgtt ttcaagcatg tataaatatt ttaatgtata aatgttgttt    840

aaaatcccct caatcggtat ctcctgattg agaaaataca cagtgaccaa tagctaatag    900

gaattcagta ttgctttcaa agaaatgtgc atattaatca ctgtagcatc tgcatacatt    960

tgaaacacgg agtaatacag gtctgtgcaa gaattagcag cttgttcctt gctaataatg   1020

acttgtgtca tctggaaggc ccccaagagc ccatggtcta caggtggaat gaccaccact   1080

tgggagtgag ctgatggaga gcacccagca ggtctcctcc atcttcctgg ttcctgtgct   1140

caccataggg ctggtgtaca ttgggccatt aataaacgtt tgttgaacaa attaa        1195


<210>  5537
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  5537

Met Val Gly Asn Asp Thr Leu Tyr Lys Ser Lys Asn His Ile Leu Cys 
1               5                   10                  15


Pro Leu Gln Thr Asn Ile Phe Val Pro Glu Val Gln Ile Arg Gly Ala 
            20                  25                  30


Ser Asn Ser Leu Lys Ile Leu Lys Met Ile Phe Phe Ser Lys Met Leu 
        35                  40                  45


Ser Trp Phe Leu Leu Asn Phe Leu Phe Ser 
    50                  55


<210>  5538
<211>  4021
<212>  DNA
<213>  Homo sapiens

<400>  5538
ggtgatcact gttggaaggc agctgcttga ggtccaaggc agtcagtgtc ccctctcttt     60

tgcctcggga cagctggtat ttatcagact cctaagaagt tttccttgct ccctagtaga    120

agagagagat tatgcagcgg gcttttgatt gatccaatgg gaattacatt gatctggtgt    180

ctggccttgg ttcttatcaa gtggatcacc tctaagaggc gtggagctat ttcctatgac    240

agttctgatc agactgcatt atacattcgt atgctaggag atgtacgtgt aaggagccga    300

gcaggatttg aatcagaaag aagaggttct cacccatata ttgattttcg tattttccac    360

tctcaatctg aaattgaagt gtctgtctct gcaaggaata tcagaaggct actaagtttc    420

cagcgatatc ttagatcttc acgctttttt cgtggtactg cggtttcaaa ttccctaaac    480

attttagatg atgattataa tggacaagcc aagtgtatgc tggaaaaagt tggaaattgg    540

aattttgata tctttctatt tgatagacta acaaatggaa atagtctagt aagcttaacc    600

tttcatttat ttagtcttca tggattaatt gagtacttcc atttagatat gatgaaactt    660

cgtagatttt tagttatgat tcaagaagat taccacagtc aaaatcctta ccataacgca    720

gtccacgctg cggatgttac tcaggccatg cactgttact taaaggaacc taagcttgcc    780

aattctgtaa ctccttggga tatcttgctg agcttaattg cagctgccac tcatgatctg    840

gatcatccag gtgttaatca acctttcctt attaaaacta accattactt ggcaacttta    900

tacaagaata cctcagtact ggaaaatcac cactggagat ctgcagtggg cttattgaga    960

gaatcaggct tattctcaca tctgccatta gaaagcaggc aacaaatgga gacacagata   1020

ggtgctctga tactagccac agacatcagt cgccagaatg agtatctgtc tttgtttagg   1080

tcccatttgg atagaggtga tttatgccta gaagacacca gacacagaca tttggtttta   1140

cagatggctt tgaaatgtgc tgatatttgt aacccatgtc ggacgtggga attaagcaag   1200

cagtggagtg aaaaagtaac ggaggaattc ttccatcaag gcaaatatag aaaaaaaata   1260

tcatttgggt gtgagtccac tttgcgatcg tcacactgaa tctattgcca acatccagat   1320

tggttttatg acttacctag tggagccttt atttacagaa tgggccaggt tttccaatac   1380

aaggctatcc cagacaatgc ttggacacgt ggggctgaat aaagccagct ggaagggact   1440

gcagagagaa cagtcgagca gtgaggacac tgatgctgca tttgagttga actcacagtt   1500

attacctcag gaaaatcggt tatcataacc cccagaacca gtgggacaaa ctgcctcctg   1560

gaggttttta gaaatgtgaa atggggtctt gaggtgagag aacttaactc ttgactgcca   1620

aggtttccaa gtgagtgatg ccagccagca ttatttattt ccaagatttc ctctgttgga   1680

tcatttgaac ccacttgtta attgcaagac ccgaacatac agcaatatga atttggcttt   1740

catgtgaaac cttgaatatg caaagcccag caggagagaa tccgaaagga gtaacaaagg   1800

aagttttgat atgtgccacg actttttcaa agcatctaat cttcaaaacg tgaaacttga   1860

attgttcagc aacaatctct tggaatttaa ccagtctgat gcaacaatgt gtatcttgta   1920

ccttccacta agttctctct gagaaaatgg aaatgtgaag tgcccagcct ctgctgcctc   1980

tggcaagaca atgtttacaa atcaactctg aaaatattgg ttctaaattg ccttggagca   2040

tgattgtgaa ggaaccactc aaacaaattt aaagatcaaa ctttagactg cagctctttc   2100

cccctggttt gcctttttct tctttggatg ccaccaaagc ctcccatttg ctatagtttt   2160

atttcatgca ctggaaactg agcatttatc gtagagtacc gccaagcttt cactccagtg   2220

ccgtttggca atgcaatttt ttttagcaat tagtttttaa tttggggtgg gaggggaaga   2280

acaccaatgt cctagctgta ttatgattct gcagtgaaga cattgcatgt tgttttcact   2340

actgtacact tgacctgcac atgcgagaaa aaggtggaat gtttaaaaca ccataatcag   2400

ctcagggtat ttgccaatct gaaataaaag tgggatggga gagtgtgtcc ttcagatcaa   2460

gggtactaaa gtccctttcg ctgcagtgag tgagaggtat gttgtgtgtg aatgtacgga   2520

tgtgtgtttg cgtgcatgtt tgtgcatgtg tgactgtgca tgttatgttt ctccatgtgg   2580

gcaaagattt gaaatgtaag cttttattta ttattttaga atgtgacata atgagcagcc   2640

acactcgggg gaggggaagg ttggtaggta agctgtaaca gattgctcca gttgccttaa   2700

actatgcaca tagctaagtg accaaacttc ttgttttgat ttgaaaaaag tgcattgttt   2760

tcttgtccct ccctttgatg aaacgttacc ctttgacggg ccttttgatg tgaacagatg   2820

ttttctagga caaactataa ggactaattt taaacttcaa acattccact tttgtaattt   2880

gttttaaatt gttttatgta tagtaagcac aactgtaatc tagttttaag agaaaccggt   2940

gctttctttt agttcatttg tatttccctt gttactgtaa aagactgttt attaattgtt   3000

tacagtttgt tgcaacagcc attttcttgg gagaaagctt gagtgtaaag ccatttgtaa   3060

aaggctttgc catactcatt ttaatatgtg cctgttgctg ttaacttttg atgaataaaa   3120

acctatcttt tcatattttt atctttgaca tttaccttat aactcaatct tttggaaaac   3180

acaatgctaa attacaagga aatcaaagtt agcttcttgg ctcttgtaat tcatccctca   3240

gatgtttact cagtccgagc ttatctacta atgactcacc ttgcaagtga gtaagcagaa   3300

gcccagttag ggctgttgga gtcctgacta acacagggga gaggtcagct ttgagccagg   3360

ccttttgttc ctacagtggt gaactgcata agacatcagc aagtcttgca agtactaaaa   3420

tactagttgt atttatttct atcaatcatt ggccttttta aagtgataag aaaaggccac   3480

tccactctac ttgattgata tcagttgtaa acaaggtacc actgtgccat tccctatatc   3540

ttcccaggtc caactcatta gaagggatat ggtgcaaact tctaaatcaa acacattaac   3600

atattatttg tacagaagag tgttgatgtc caatagaaac agaatccaag ccacataatt   3660

ttcggttttc tagtagccac atttagaaaa catggaatta attttagtaa catctattcc   3720

aatacgtcca aaatattgta tcactttaaa atgtcaatat aaaaacaatt agatgttttt   3780

acattctttt ggggggtact aagtctttga aatccagtgt atattgtgta cttacagcac   3840

atctcaattt ggactagtca tatctcaggc acccaatatc cacatgtggc tagtggctac   3900

catattggac agtgtgggta tagaggtctg agggtagtag aggaatatgg tcagctggtc   3960

actctcgtga gatggccata ccttggccta tatttaatgt gtacagaaag tctgataact   4020

c                                                                   4021


<210>  5539
<211>  380
<212>  PRT
<213>  Homo sapiens

<400>  5539

Met Gly Ile Thr Leu Ile Trp Cys Leu Ala Leu Val Leu Ile Lys Trp 
1               5                   10                  15


Ile Thr Ser Lys Arg Arg Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln 
            20                  25                  30


Thr Ala Leu Tyr Ile Arg Met Leu Gly Asp Val Arg Val Arg Ser Arg 
        35                  40                  45


Ala Gly Phe Glu Ser Glu Arg Arg Gly Ser His Pro Tyr Ile Asp Phe 
    50                  55                  60


Arg Ile Phe His Ser Gln Ser Glu Ile Glu Val Ser Val Ser Ala Arg 
65                  70                  75                  80


Asn Ile Arg Arg Leu Leu Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg 
                85                  90                  95


Phe Phe Arg Gly Thr Ala Val Ser Asn Ser Leu Asn Ile Leu Asp Asp 
            100                 105                 110


Asp Tyr Asn Gly Gln Ala Lys Cys Met Leu Glu Lys Val Gly Asn Trp 
        115                 120                 125


Asn Phe Asp Ile Phe Leu Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu 
    130                 135                 140


Val Ser Leu Thr Phe His Leu Phe Ser Leu His Gly Leu Ile Glu Tyr 
145                 150                 155                 160


Phe His Leu Asp Met Met Lys Leu Arg Arg Phe Leu Val Met Ile Gln 
                165                 170                 175


Glu Asp Tyr His Ser Gln Asn Pro Tyr His Asn Ala Val His Ala Ala 
            180                 185                 190


Asp Val Thr Gln Ala Met His Cys Tyr Leu Lys Glu Pro Lys Leu Ala 
        195                 200                 205


Asn Ser Val Thr Pro Trp Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala 
    210                 215                 220


Thr His Asp Leu Asp His Pro Gly Val Asn Gln Pro Phe Leu Ile Lys 
225                 230                 235                 240


Thr Asn His Tyr Leu Ala Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu 
                245                 250                 255


Asn His His Trp Arg Ser Ala Val Gly Leu Leu Arg Glu Ser Gly Leu 
            260                 265                 270


Phe Ser His Leu Pro Leu Glu Ser Arg Gln Gln Met Glu Thr Gln Ile 
        275                 280                 285


Gly Ala Leu Ile Leu Ala Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu 
    290                 295                 300


Ser Leu Phe Arg Ser His Leu Asp Arg Gly Asp Leu Cys Leu Glu Asp 
305                 310                 315                 320


Thr Arg His Arg His Leu Val Leu Gln Met Ala Leu Lys Cys Ala Asp 
                325                 330                 335


Ile Cys Asn Pro Cys Arg Thr Trp Glu Leu Ser Lys Gln Trp Ser Glu 
            340                 345                 350


Lys Val Thr Glu Glu Phe Phe His Gln Gly Lys Tyr Arg Lys Lys Ile 
        355                 360                 365


Ser Phe Gly Cys Glu Ser Thr Leu Arg Ser Ser His 
    370                 375                 380


<210>  5540
<211>  4396
<212>  DNA
<213>  Homo sapiens

<400>  5540
gagctggtcg ctgctcctga gtcccgcgcg ccctgggtct ggccgctggc tccagctgtc     60

ttttcttgca ctgctttgct ccgttcgtgc tgcgctcgaa ctctgcagtc cgggtacctg    120

ctcctctcgg ccgaggagcc ccagggcggc ggggttccct ttccgacttt gcctgtgctg    180

gccccgcttg caccccgtcc cccctcgcct ggagcgaggc gcgcgccggt cctggtaatt    240

ggcgccgcgg ccgccgcgga gccttcccgc cggcggcccg agcggagggc tggggttggg    300

gaggcgtgag cgcggcttcc cagcccgggg tcggtccccg cccgccctgc ccccgtctcg    360

gcccggagcc cccgagccgc ggccccctcc cactgcaggg gccggcggcc gcggcagggc    420

gggcgccgcg cggaggcagg gcgggcgtat tcaatggaag tgtgttacca gctgccggta    480

ctgcccctgg acaggccggt cccccagcac gtcctcagcc gccgaggagc catcagcttc    540

agctccagct ccgctctctt cggctgcccc aatccccggc agctctctca gaggcgtgga    600

gctatttcct atgacagttc tgatcagact gcattataca ttcgtatgct aggagatgta    660

cgtgtaagga gccgagcagg atttgaatca gaaagaagag gttctcaccc atatattgat    720

tttcgtattt tccactctca atctgaaatt gaagtgtctg tctctgcaag gaatatcaga    780

aggctactaa gtttccagcg atatcttaga tcttcacgct tttttcgtgg tactgcggtt    840

tcaaattccc taaacatttt agatgatgat tataatggac aagccaagtg tatgctggaa    900

aaagttggaa attggaattt tgatatcttt ctatttgata gactaacaaa tggaaatagt    960

ctagtaagct taacctttca tttatttagt cttcatggat taattgagta cttccattta   1020

gatatgatga aacttcgtag atttttagtt atgattcaag aagattacca cagtcaaaat   1080

ccttaccata acgcagtcca cgctgcggat gttactcagg ccatgcactg ttacttaaag   1140

gaacctaagc ttgccaattc tgtaactcct tgggatatct tgctgagctt aattgcagct   1200

gccactcatg atctggatca tccaggtgtt aatcaacctt tccttattaa aactaaccat   1260

tacttggcaa ctttatacaa gaatacctca gtactggaaa atcaccactg gagatctgca   1320

gtgggcttat tgagagaatc aggcttattc tcacatctgc cattagaaag caggcaacaa   1380

atggagacac agataggtgc tctgatacta gccacagaca tcagtcgcca gaatgagtat   1440

ctgtctttgt ttaggtccca tttggataga ggtgatttat gcctagaaga caccagacac   1500

agacatttgg ttttacagat ggctttgaaa tgtgctgata tttgtaaccc atgtcggacg   1560

tgggaattaa gcaagcagtg gagtgaaaaa gtaacggagg aattcttcca tcaaggcaaa   1620

tatagaaaaa aaatatcatt tgggtgtgag tccactttgc gatcgtcaca ctgaatctat   1680

tgccaacatc cagattggtt ttatgactta cctagtggag cctttattta cagaatgggc   1740

caggttttcc aatacaaggc tatcccagac aatgcttgga cacgtggggc tgaataaagc   1800

cagctggaag ggactgcaga gagaacagtc gagcagtgag gacactgatg ctgcatttga   1860

gttgaactca cagttattac ctcaggaaaa tcggttatca taacccccag aaccagtggg   1920

acaaactgcc tcctggaggt ttttagaaat gtgaaatggg gtcttgaggt gagagaactt   1980

aactcttgac tgccaaggtt tccaagtgag tgatgccagc cagcattatt tatttccaag   2040

atttcctctg ttggatcatt tgaacccact tgttaattgc aagacccgaa catacagcaa   2100

tatgaatttg gctttcatgt gaaaccttga atatgcaaag cccagcagga gagaatccga   2160

aaggagtaac aaaggaagtt ttgatatgtg ccacgacttt ttcaaagcat ctaatcttca   2220

aaacgtgaaa cttgaattgt tcagcaacaa tctcttggaa tttaaccagt ctgatgcaac   2280

aatgtgtatc ttgtaccttc cactaagttc tctctgagaa aatggaaatg tgaagtgccc   2340

agcctctgct gcctctggca agacaatgtt tacaaatcaa ctctgaaaat attggttcta   2400

aattgccttg gagcatgatt gtgaaggaac cactcaaaca aatttaaaga tcaaacttta   2460

gactgcagct ctttccccct ggtttgcctt tttcttcttt ggatgccacc aaagcctccc   2520

atttgctata gttttatttc atgcactgga aactgagcat ttatcgtaga gtaccgccaa   2580

gctttcactc cagtgccgtt tggcaatgca atttttttta gcaattagtt tttaatttgg   2640

ggtgggaggg gaagaacacc aatgtcctag ctgtattatg attctgcagt gaagacattg   2700

catgttgttt tcactactgt acacttgacc tgcacatgcg agaaaaaggt ggaatgttta   2760

aaacaccata atcagctcag ggtatttgcc aatctgaaat aaaagtggga tgggagagtg   2820

tgtccttcag atcaagggta ctaaagtccc tttcgctgca gtgagtgaga ggtatgttgt   2880

gtgtgaatgt acggatgtgt gtttgcgtgc atgtttgtgc atgtgtgact gtgcatgtta   2940

tgtttctcca tgtgggcaaa gatttgaaat gtaagctttt atttattatt ttagaatgtg   3000

acataatgag cagccacact cgggggaggg gaaggttggt aggtaagctg taacagattg   3060

ctccagttgc cttaaactat gcacatagct aagtgaccaa acttcttgtt ttgatttgaa   3120

aaaagtgcat tgttttcttg tccctccctt tgatgaaacg ttaccctttg acgggccttt   3180

tgatgtgaac agatgttttc taggacaaac tataaggact aattttaaac ttcaaacatt   3240

ccacttttgt aatttgtttt aaattgtttt atgtatagta agcacaactg taatctagtt   3300

ttaagagaaa ccggtgcttt cttttagttc atttgtattt cccttgttac tgtaaaagac   3360

tgtttattaa ttgtttacag tttgttgcaa cagccatttt cttgggagaa agcttgagtg   3420

taaagccatt tgtaaaaggc tttgccatac tcattttaat atgtgcctgt tgctgttaac   3480

ttttgatgaa taaaaaccta tcttttcata tttttatctt tgacatttac cttataactc   3540

aatcttttgg aaaacacaat gctaaattac aaggaaatca aagttagctt cttggctctt   3600

gtaattcatc cctcagatgt ttactcagtc cgagcttatc tactaatgac tcaccttgca   3660

agtgagtaag cagaagccca gttagggctg ttggagtcct gactaacaca ggggagaggt   3720

cagctttgag ccaggccttt tgttcctaca gtggtgaact gcataagaca tcagcaagtc   3780

ttgcaagtac taaaatacta gttgtattta tttctatcaa tcattggcct ttttaaagtg   3840

ataagaaaag gccactccac tctacttgat tgatatcagt tgtaaacaag gtaccactgt   3900

gccattccct atatcttccc aggtccaact cattagaagg gatatggtgc aaacttctaa   3960

atcaaacaca ttaacatatt atttgtacag aagagtgttg atgtccaata gaaacagaat   4020

ccaagccaca taattttcgg ttttctagta gccacattta gaaaacatgg aattaatttt   4080

agtaacatct attccaatac gtccaaaata ttgtatcact ttaaaatgtc aatataaaaa   4140

caattagatg tttttacatt cttttggggg gtactaagtc tttgaaatcc agtgtatatt   4200

gtgtacttac agcacatctc aatttggact agtcatatct caggcaccca atatccacat   4260

gtggctagtg gctaccatat tggacagtgt gggtatagag gtctgagggt agtagaggaa   4320

tatggtcagc tggtcactct cgtgagatgg ccataccttg gcctatattt aatgtgtaca   4380

gaaagtctga taactc                                                   4396


<210>  5541
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  5541

Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro Val 
1               5                   10                  15


Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser Ser Ser 
            20                  25                  30


Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser Gln Arg Arg 
        35                  40                  45


Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala Leu Tyr Ile Arg 
    50                  55                  60


Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala Gly Phe Glu Ser Glu 
65                  70                  75                  80


Arg Arg Gly Ser His Pro Tyr Ile Asp Phe Arg Ile Phe His Ser Gln 
                85                  90                  95


Ser Glu Ile Glu Val Ser Val Ser Ala Arg Asn Ile Arg Arg Leu Leu 
            100                 105                 110


Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg Phe Phe Arg Gly Thr Ala 
        115                 120                 125


Val Ser Asn Ser Leu Asn Ile Leu Asp Asp Asp Tyr Asn Gly Gln Ala 
    130                 135                 140


Lys Cys Met Leu Glu Lys Val Gly Asn Trp Asn Phe Asp Ile Phe Leu 
145                 150                 155                 160


Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His 
                165                 170                 175


Leu Phe Ser Leu His Gly Leu Ile Glu Tyr Phe His Leu Asp Met Met 
            180                 185                 190


Lys Leu Arg Arg Phe Leu Val Met Ile Gln Glu Asp Tyr His Ser Gln 
        195                 200                 205


Asn Pro Tyr His Asn Ala Val His Ala Ala Asp Val Thr Gln Ala Met 
    210                 215                 220


His Cys Tyr Leu Lys Glu Pro Lys Leu Ala Asn Ser Val Thr Pro Trp 
225                 230                 235                 240


Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala Thr His Asp Leu Asp His 
                245                 250                 255


Pro Gly Val Asn Gln Pro Phe Leu Ile Lys Thr Asn His Tyr Leu Ala 
            260                 265                 270


Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu Asn His His Trp Arg Ser 
        275                 280                 285


Ala Val Gly Leu Leu Arg Glu Ser Gly Leu Phe Ser His Leu Pro Leu 
    290                 295                 300


Glu Ser Arg Gln Gln Met Glu Thr Gln Ile Gly Ala Leu Ile Leu Ala 
305                 310                 315                 320


Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu Ser Leu Phe Arg Ser His 
                325                 330                 335


Leu Asp Arg Gly Asp Leu Cys Leu Glu Asp Thr Arg His Arg His Leu 
            340                 345                 350


Val Leu Gln Met Ala Leu Lys Cys Ala Asp Ile Cys Asn Pro Cys Arg 
        355                 360                 365


Thr Trp Glu Leu Ser Lys Gln Trp Ser Glu Lys Val Thr Glu Glu Phe 
    370                 375                 380


Phe His Gln Gly Lys Tyr Arg Lys Lys Ile Ser Phe Gly Cys Glu Ser 
385                 390                 395                 400


Thr Leu Arg Ser Ser His 
                405


<210>  5542
<211>  3147
<212>  DNA
<213>  Homo sapiens

<400>  5542
ggtgatcact gttggaaggc agctgcttga ggtccaaggc agtcagtgtc ccctctcttt     60

tgcctcggga cagctggtat ttatcagact cctaagaagt tttccttgct ccctagtaga    120

agagagagat tatgcagcgg gcttttgatt gatccaatgg gaattacatt gatctggtgt    180

ctggccttgg ttcttatcaa gtggatcacc tctaagaggc gtggagctat ttcctatgac    240

agttctgatc agactgcatt atacattcgt atgctaggag atgtacgtgt aaggagccga    300

gcaggatttg aatcagaaag aagaggttct cacccatata ttgattttcg tattttccac    360

tctcaatctg aaattgaagt gtctgtctct gcaaggaata tcagaaggct actaagtttc    420

cagcgatatc ttagatcttc acgctttttt cgtggtactg cggtttcaaa ttccctaaac    480

attttagatg atgattataa tggacaagcc aagtgtatgc tggaaaaagt tggaaattgg    540

aattttgata tctttctatt tgatagacta acaaatggaa atagtctagt aagcttaacc    600

tttcatttat ttagtcttca tggattaatt gagtacttcc atttagatat gatgaaactt    660

cgtagatttt tagttatgat tcaagaagat taccacagtc aaaatcctta ccataacgca    720

gtccacgctg cggatgttac tcaggccatg cactgttact taaaggaacc taagcttgcc    780

aattctgtaa ctccttggga tatcttgctg agcttaattg cagctgccac tcatgatctg    840

gatcatccag gtgttaatca acctttcctt attaaaacta accattactt ggcaacttta    900

tacaagaata cctcagtact ggaaaatcac cactggagat ctgcagtggg cttattgaga    960

gaatcaggct tattctcaca tctgccatta gaaagcaggc aacaaatgga gacacagata   1020

ggtgctctga tactagccac agacatcagt cgccagaatg agtatctgtc tttgtttagg   1080

tcccatttgg atagaggtga tttatgccta gaagacacca gacacagaca tttggtttta   1140

cagatggctt tgaaatgtgc tgatatttgt aacccatgtc ggacgtggga attaagcaag   1200

cagtggagtg aaaaagtaac ggaggaattc ttccatcaag gcaaatatag aaaaaaaata   1260

tcatttgggt gtgagtccac tttgcgatcg tcacactgaa tctattgcca acatccagat   1320

tggttttatg acttacctag tggagccttt atttacagaa tgggccaggt tttccaatac   1380

aaggctatcc cagacaatgc ttggacacgt ggggctgaat aaagccagct ggaagggact   1440

gcagagagaa cagtcgagca gtgaggacac tgatgctgca tttgagttga actcacagtt   1500

attacctcag gaaaatcggt tatcataacc cccagaacca gtgggacaaa ctgcctcctg   1560

gaggttttta gaaatgtgaa atggggtctt gaggtgagag aacttaactc ttgactgcca   1620

aggtttccaa gtgagtgatg ccagccagca ttatttattt ccaagatttc ctctgttgga   1680

tcatttgaac ccacttgtta attgcaagac ccgaacatac agcaatatga atttggcttt   1740

catgtgaaac cttgaatatg caaagcccag caggagagaa tccgaaagga gtaacaaagg   1800

aagttttgat atgtgccacg actttttcaa agcatctaat cttcaaaacg tgaaacttga   1860

attgttcagc aacaatctct tggaatttaa ccagtctgat gcaacaatgt gtatcttgta   1920

ccttccacta agttctctct gagaaaatgg aaatgtgaag tgcccagcct ctgctgcctc   1980

tggcaagaca atgtttacaa atcaactctg aaaatattgg ttctaaattg ccttggagca   2040

tgattgtgaa ggaaccactc aaacaaattt aaagatcaaa ctttagactg cagctctttc   2100

cccctggttt gcctttttct tctttggatg ccaccaaagc ctcccatttg ctatagtttt   2160

atttcatgca ctggaaactg agcatttatc gtagagtacc gccaagcttt cactccagtg   2220

ccgtttggca atgcaatttt ttttagcaat tagtttttaa tttggggtgg gaggggaaga   2280

acaccaatgt cctagctgta ttatgattct gcagtgaaga cattgcatgt tgttttcact   2340

actgtacact tgacctgcac atgcgagaaa aaggtggaat gtttaaaaca ccataatcag   2400

ctcagggtat ttgccaatct gaaataaaag tgggatggga gagtgtgtcc ttcagatcaa   2460

gggtactaaa gtccctttcg ctgcagtgag tgagaggtat gttgtgtgtg aatgtacgga   2520

tgtgtgtttg cgtgcatgtt tgtgcatgtg tgactgtgca tgttatgttt ctccatgtgg   2580

gcaaagattt gaaatgtaag cttttattta ttattttaga atgtgacata atgagcagcc   2640

acactcgggg gaggggaagg ttggtaggta agctgtaaca gattgctcca gttgccttaa   2700

actatgcaca tagctaagtg accaaacttc ttgttttgat ttgaaaaaag tgcattgttt   2760

tcttgtccct ccctttgatg aaacgttacc ctttgacggg ccttttgatg tgaacagatg   2820

ttttctagga caaactataa ggactaattt taaacttcaa acattccact tttgtaattt   2880

gttttaaatt gttttatgta tagtaagcac aactgtaatc tagttttaag agaaaccggt   2940

gctttctttt agttcatttg tatttccctt gttactgtaa aagactgttt attaattgtt   3000

tacagtttgt tgcaacagcc attttcttgg gagaaagctt gagtgtaaag ccatttgtaa   3060

aaggctttgc catactcatt ttaatatgtg cctgttgctg ttaacttttg atgaataaaa   3120

acctatcttt tcatattttt atctttg                                       3147


<210>  5543
<211>  380
<212>  PRT
<213>  Homo sapiens

<400>  5543

Met Gly Ile Thr Leu Ile Trp Cys Leu Ala Leu Val Leu Ile Lys Trp 
1               5                   10                  15


Ile Thr Ser Lys Arg Arg Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln 
            20                  25                  30


Thr Ala Leu Tyr Ile Arg Met Leu Gly Asp Val Arg Val Arg Ser Arg 
        35                  40                  45


Ala Gly Phe Glu Ser Glu Arg Arg Gly Ser His Pro Tyr Ile Asp Phe 
    50                  55                  60


Arg Ile Phe His Ser Gln Ser Glu Ile Glu Val Ser Val Ser Ala Arg 
65                  70                  75                  80


Asn Ile Arg Arg Leu Leu Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg 
                85                  90                  95


Phe Phe Arg Gly Thr Ala Val Ser Asn Ser Leu Asn Ile Leu Asp Asp 
            100                 105                 110


Asp Tyr Asn Gly Gln Ala Lys Cys Met Leu Glu Lys Val Gly Asn Trp 
        115                 120                 125


Asn Phe Asp Ile Phe Leu Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu 
    130                 135                 140


Val Ser Leu Thr Phe His Leu Phe Ser Leu His Gly Leu Ile Glu Tyr 
145                 150                 155                 160


Phe His Leu Asp Met Met Lys Leu Arg Arg Phe Leu Val Met Ile Gln 
                165                 170                 175


Glu Asp Tyr His Ser Gln Asn Pro Tyr His Asn Ala Val His Ala Ala 
            180                 185                 190


Asp Val Thr Gln Ala Met His Cys Tyr Leu Lys Glu Pro Lys Leu Ala 
        195                 200                 205


Asn Ser Val Thr Pro Trp Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala 
    210                 215                 220


Thr His Asp Leu Asp His Pro Gly Val Asn Gln Pro Phe Leu Ile Lys 
225                 230                 235                 240


Thr Asn His Tyr Leu Ala Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu 
                245                 250                 255


Asn His His Trp Arg Ser Ala Val Gly Leu Leu Arg Glu Ser Gly Leu 
            260                 265                 270


Phe Ser His Leu Pro Leu Glu Ser Arg Gln Gln Met Glu Thr Gln Ile 
        275                 280                 285


Gly Ala Leu Ile Leu Ala Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu 
    290                 295                 300


Ser Leu Phe Arg Ser His Leu Asp Arg Gly Asp Leu Cys Leu Glu Asp 
305                 310                 315                 320


Thr Arg His Arg His Leu Val Leu Gln Met Ala Leu Lys Cys Ala Asp 
                325                 330                 335


Ile Cys Asn Pro Cys Arg Thr Trp Glu Leu Ser Lys Gln Trp Ser Glu 
            340                 345                 350


Lys Val Thr Glu Glu Phe Phe His Gln Gly Lys Tyr Arg Lys Lys Ile 
        355                 360                 365


Ser Phe Gly Cys Glu Ser Thr Leu Arg Ser Ser His 
    370                 375                 380


<210>  5544
<211>  3522
<212>  DNA
<213>  Homo sapiens

<400>  5544
gagctggtcg ctgctcctga gtcccgcgcg ccctgggtct ggccgctggc tccagctgtc     60

ttttcttgca ctgctttgct ccgttcgtgc tgcgctcgaa ctctgcagtc cgggtacctg    120

ctcctctcgg ccgaggagcc ccagggcggc ggggttccct ttccgacttt gcctgtgctg    180

gccccgcttg caccccgtcc cccctcgcct ggagcgaggc gcgcgccggt cctggtaatt    240

ggcgccgcgg ccgccgcgga gccttcccgc cggcggcccg agcggagggc tggggttggg    300

gaggcgtgag cgcggcttcc cagcccgggg tcggtccccg cccgccctgc ccccgtctcg    360

gcccggagcc cccgagccgc ggccccctcc cactgcaggg gccggcggcc gcggcagggc    420

gggcgccgcg cggaggcagg gcgggcgtat tcaatggaag tgtgttacca gctgccggta    480

ctgcccctgg acaggccggt cccccagcac gtcctcagcc gccgaggagc catcagcttc    540

agctccagct ccgctctctt cggctgcccc aatccccggc agctctctca gaggcgtgga    600

gctatttcct atgacagttc tgatcagact gcattataca ttcgtatgct aggagatgta    660

cgtgtaagga gccgagcagg atttgaatca gaaagaagag gttctcaccc atatattgat    720

tttcgtattt tccactctca atctgaaatt gaagtgtctg tctctgcaag gaatatcaga    780

aggctactaa gtttccagcg atatcttaga tcttcacgct tttttcgtgg tactgcggtt    840

tcaaattccc taaacatttt agatgatgat tataatggac aagccaagtg tatgctggaa    900

aaagttggaa attggaattt tgatatcttt ctatttgata gactaacaaa tggaaatagt    960

ctagtaagct taacctttca tttatttagt cttcatggat taattgagta cttccattta   1020

gatatgatga aacttcgtag atttttagtt atgattcaag aagattacca cagtcaaaat   1080

ccttaccata acgcagtcca cgctgcggat gttactcagg ccatgcactg ttacttaaag   1140

gaacctaagc ttgccaattc tgtaactcct tgggatatct tgctgagctt aattgcagct   1200

gccactcatg atctggatca tccaggtgtt aatcaacctt tccttattaa aactaaccat   1260

tacttggcaa ctttatacaa gaatacctca gtactggaaa atcaccactg gagatctgca   1320

gtgggcttat tgagagaatc aggcttattc tcacatctgc cattagaaag caggcaacaa   1380

atggagacac agataggtgc tctgatacta gccacagaca tcagtcgcca gaatgagtat   1440

ctgtctttgt ttaggtccca tttggataga ggtgatttat gcctagaaga caccagacac   1500

agacatttgg ttttacagat ggctttgaaa tgtgctgata tttgtaaccc atgtcggacg   1560

tgggaattaa gcaagcagtg gagtgaaaaa gtaacggagg aattcttcca tcaaggcaaa   1620

tatagaaaaa aaatatcatt tgggtgtgag tccactttgc gatcgtcaca ctgaatctat   1680

tgccaacatc cagattggtt ttatgactta cctagtggag cctttattta cagaatgggc   1740

caggttttcc aatacaaggc tatcccagac aatgcttgga cacgtggggc tgaataaagc   1800

cagctggaag ggactgcaga gagaacagtc gagcagtgag gacactgatg ctgcatttga   1860

gttgaactca cagttattac ctcaggaaaa tcggttatca taacccccag aaccagtggg   1920

acaaactgcc tcctggaggt ttttagaaat gtgaaatggg gtcttgaggt gagagaactt   1980

aactcttgac tgccaaggtt tccaagtgag tgatgccagc cagcattatt tatttccaag   2040

atttcctctg ttggatcatt tgaacccact tgttaattgc aagacccgaa catacagcaa   2100

tatgaatttg gctttcatgt gaaaccttga atatgcaaag cccagcagga gagaatccga   2160

aaggagtaac aaaggaagtt ttgatatgtg ccacgacttt ttcaaagcat ctaatcttca   2220

aaacgtgaaa cttgaattgt tcagcaacaa tctcttggaa tttaaccagt ctgatgcaac   2280

aatgtgtatc ttgtaccttc cactaagttc tctctgagaa aatggaaatg tgaagtgccc   2340

agcctctgct gcctctggca agacaatgtt tacaaatcaa ctctgaaaat attggttcta   2400

aattgccttg gagcatgatt gtgaaggaac cactcaaaca aatttaaaga tcaaacttta   2460

gactgcagct ctttccccct ggtttgcctt tttcttcttt ggatgccacc aaagcctccc   2520

atttgctata gttttatttc atgcactgga aactgagcat ttatcgtaga gtaccgccaa   2580

gctttcactc cagtgccgtt tggcaatgca atttttttta gcaattagtt tttaatttgg   2640

ggtgggaggg gaagaacacc aatgtcctag ctgtattatg attctgcagt gaagacattg   2700

catgttgttt tcactactgt acacttgacc tgcacatgcg agaaaaaggt ggaatgttta   2760

aaacaccata atcagctcag ggtatttgcc aatctgaaat aaaagtggga tgggagagtg   2820

tgtccttcag atcaagggta ctaaagtccc tttcgctgca gtgagtgaga ggtatgttgt   2880

gtgtgaatgt acggatgtgt gtttgcgtgc atgtttgtgc atgtgtgact gtgcatgtta   2940

tgtttctcca tgtgggcaaa gatttgaaat gtaagctttt atttattatt ttagaatgtg   3000

acataatgag cagccacact cgggggaggg gaaggttggt aggtaagctg taacagattg   3060

ctccagttgc cttaaactat gcacatagct aagtgaccaa acttcttgtt ttgatttgaa   3120

aaaagtgcat tgttttcttg tccctccctt tgatgaaacg ttaccctttg acgggccttt   3180

tgatgtgaac agatgttttc taggacaaac tataaggact aattttaaac ttcaaacatt   3240

ccacttttgt aatttgtttt aaattgtttt atgtatagta agcacaactg taatctagtt   3300

ttaagagaaa ccggtgcttt cttttagttc atttgtattt cccttgttac tgtaaaagac   3360

tgtttattaa ttgtttacag tttgttgcaa cagccatttt cttgggagaa agcttgagtg   3420

taaagccatt tgtaaaaggc tttgccatac tcattttaat atgtgcctgt tgctgttaac   3480

ttttgatgaa taaaaaccta tcttttcata tttttatctt tg                      3522


<210>  5545
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  5545

Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro Val 
1               5                   10                  15


Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser Ser Ser 
            20                  25                  30


Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser Gln Arg Arg 
        35                  40                  45


Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala Leu Tyr Ile Arg 
    50                  55                  60


Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala Gly Phe Glu Ser Glu 
65                  70                  75                  80


Arg Arg Gly Ser His Pro Tyr Ile Asp Phe Arg Ile Phe His Ser Gln 
                85                  90                  95


Ser Glu Ile Glu Val Ser Val Ser Ala Arg Asn Ile Arg Arg Leu Leu 
            100                 105                 110


Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg Phe Phe Arg Gly Thr Ala 
        115                 120                 125


Val Ser Asn Ser Leu Asn Ile Leu Asp Asp Asp Tyr Asn Gly Gln Ala 
    130                 135                 140


Lys Cys Met Leu Glu Lys Val Gly Asn Trp Asn Phe Asp Ile Phe Leu 
145                 150                 155                 160


Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His 
                165                 170                 175


Leu Phe Ser Leu His Gly Leu Ile Glu Tyr Phe His Leu Asp Met Met 
            180                 185                 190


Lys Leu Arg Arg Phe Leu Val Met Ile Gln Glu Asp Tyr His Ser Gln 
        195                 200                 205


Asn Pro Tyr His Asn Ala Val His Ala Ala Asp Val Thr Gln Ala Met 
    210                 215                 220


His Cys Tyr Leu Lys Glu Pro Lys Leu Ala Asn Ser Val Thr Pro Trp 
225                 230                 235                 240


Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala Thr His Asp Leu Asp His 
                245                 250                 255


Pro Gly Val Asn Gln Pro Phe Leu Ile Lys Thr Asn His Tyr Leu Ala 
            260                 265                 270


Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu Asn His His Trp Arg Ser 
        275                 280                 285


Ala Val Gly Leu Leu Arg Glu Ser Gly Leu Phe Ser His Leu Pro Leu 
    290                 295                 300


Glu Ser Arg Gln Gln Met Glu Thr Gln Ile Gly Ala Leu Ile Leu Ala 
305                 310                 315                 320


Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu Ser Leu Phe Arg Ser His 
                325                 330                 335


Leu Asp Arg Gly Asp Leu Cys Leu Glu Asp Thr Arg His Arg His Leu 
            340                 345                 350


Val Leu Gln Met Ala Leu Lys Cys Ala Asp Ile Cys Asn Pro Cys Arg 
        355                 360                 365


Thr Trp Glu Leu Ser Lys Gln Trp Ser Glu Lys Val Thr Glu Glu Phe 
    370                 375                 380


Phe His Gln Gly Lys Tyr Arg Lys Lys Ile Ser Phe Gly Cys Glu Ser 
385                 390                 395                 400


Thr Leu Arg Ser Ser His 
                405


<210>  5546
<211>  1556
<212>  DNA
<213>  Homo sapiens

<400>  5546
tcaagtgtac agtagtgaaa acaacatgca atgtcttcac tgcagaatca taatacagct     60

aggacattgg tgttcttccc ctcccacccc aaattaaaaa ctaattgcta aaaaaaattg    120

cattgccaaa cggcactgga gtgaaagctt ggcggtactc tacgataaat gctcagtttc    180

cagtgcatga aataaaacta tagcaaatgg gaggctttgg tggcatccaa agaagaaaaa    240

ggcaaaccag ggggaaagag ctgcagtcta aagtttgatc tttaaatttg tttgagtggt    300

tccttcacaa tcatgctcca aggcaattta gaaccaatat tttcagagtt gatttgtaaa    360

cattgtcttg ccagaggcag cagaggctgg gcacttcaca tttccatttt ctcagagaga    420

acttagtgga aggtacaaga tacacattgt tgcatcagac tggttaaatt ccaagagatt    480

gttgctgaac aattcaagtt tcacgttttg aagattagat gctttgaaaa agtcgtggca    540

catatcaaaa cttcctttgt tactcctttc ggattctctc ctgctgggct ttgcatattc    600

aaggtttcac atgaaagcca aattcatatt gctgtatgtt cgggtcttgc aattaacaag    660

tgggttcaaa tgatccaaca gaggaaatct tggaaataaa taatgctggc tggcatcact    720

cacttggaaa ccttggcagt caagagttaa gttctctcac ctcaagaccc catttcacat    780

ttctaaaaac ctccaggagg cagtttgtcc cactggttct gggggttatg ataaccgatt    840

ttcctgaggt aataactgtg agttcaactc aaatgcagca tcagtgtcct cactgctcga    900

ctgttctctc tgcagtccct tccagctggc tttattcagc cccacgtgtc caagcattgt    960

ctgggatagc cttgtattgg aaaacctggc ccattctgta aataaaggct ccactagatt   1020

tcacaggacg ccttgtcaaa tgccttactc ttatccagta catattttct tgttcaacaa   1080

aattagtatt cctatcaaag aaagaaactg tattagttca acatgacttg tacatactgc   1140

ccctatgttg gggagtagta atcactgctt ggtgagttgt taagaggctg ggatttgatg   1200

tccgaaagac ctggatttga agcccaacac caacagctgt taactgcatg aagtgggcaa   1260

accatctgaa aataaggatg ctcaaagcac cggtccccta gggttgttgt gtggagtcag   1320

cagatgtcaa caatcaccat cagatcagtg accttatccc tgacaaccca ttctagatct   1380

gtacaacact gacaagatca atagcttgag atgaacagtg aaagggatct agcttctgtt   1440

accttataaa aattacaatg ttttaaatct catttgcaag ttctcccatt aagcaaggga   1500

gtagtttact aggataaaaa gacatttaat attaaaagta actgagttga ctaccg       1556


<210>  5547
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5547

Met Ile Thr Asp Phe Pro Glu Val Ile Thr Val Ser Ser Thr Gln Met 
1               5                   10                  15


Gln His Gln Cys Pro His Cys Ser Thr Val Leu Ser Ala Val Pro Ser 
            20                  25                  30


Ser Trp Leu Tyr Ser Ala Pro Arg Val Gln Ala Leu Ser Gly Ile Ala 
        35                  40                  45


Leu Tyr Trp Lys Thr Trp Pro Ile Leu 
    50                  55


<210>  5548
<211>  4187
<212>  DNA
<213>  Homo sapiens

<400>  5548
gagctggtcg ctgctcctga gtcccgcgcg ccctgggtct ggccgctggc tccagctgtc     60

ttttcttgca ctgctttgct ccgttcgtgc tgcgctcgaa ctctgcagtc cgggtacctg    120

ctcctctcgg ccgaggagcc ccagggcggc ggggttccct ttccgacttt gcctgtgctg    180

gccccgcttg caccccgtcc cccctcgcct ggagcgaggc gcgcgccggt cctggtaatt    240

ggcgccgcgg ccgccgcgga gccttcccgc cggcggcccg agcggagggc tggggttggg    300

gaggcgtgag cgcggcttcc cagcccgggg tcggtccccg cccgccctgc ccccgtctcg    360

gcccggagcc cccgagccgc ggccccctcc cactgcaggg gccggcggcc gcggcagggc    420

gggcgccgcg cggaggcagg gcgggcgtat tcaatggaag tgtgttacca gctgccggta    480

ctgcccctgg acaggccggt cccccagcac gtcctcagcc gccgaggagc catcagcttc    540

agctccagct ccgctctctt cggctgcccc aatccccggc agctctctca gaggcgtgga    600

gctatttcct atgacagttc tgatcagact gcattataca ttcgtatgct aggagatgta    660

cgtgtaagga gccgagcagg atttgaatca gaaagaagag gttctcaccc atatattgat    720

tttcgtattt tccactctca atctgaaatt gaagtgtctg tctctgcaag gaatatcaga    780

aggctactaa gtttccagcg atatcttaga tcttcacgct tttttcgtgg tactgcggtt    840

tcaaattccc taaacatttt agatgatgat tataatggac aagccaagtg tatgctggaa    900

aaagttggaa attggaattt tgatatcttt ctatttgata gactaacaaa tggaaatagt    960

ctagtaagct taacctttca tttatttagt cttcatggat taattgagta cttccattta   1020

gatatgatga aacttcgtag atttttagtt atgattcaag aagattacca cagtcaaaat   1080

ccttaccata acgcagtcca cgctgcggat gttactcagg ccatgcactg ttacttaaag   1140

gaacctaagc ttgccaattc tgtaactcct tgggatatct tgctgagctt aattgcagct   1200

gccactcatg atctggatca tccaggtgtt aatcaacctt tccttattaa aactaaccat   1260

tacttggcaa ctttatacaa gaatacctca gtactggaaa atcaccactg gagatctgca   1320

gtgggcttat tgagagaatc aggcttattc tcacatctgc cattagaaag caggcaacaa   1380

atggagacac agataggtgc tctgatacta gccacagaca tcagtcgcca gaatgagtat   1440

ctgtctttgt ttaggtccca tttggataga ggtgatttat gcctagaaga caccagacac   1500

agacatttgg ttttacagat ggctttgaaa tgtgctgata tttgtaaccc atgtcggacg   1560

tgggaattaa gcaagcagtg gagtgaaaaa gtaacggagg aattcttcca tcaaggcaaa   1620

tatagaaaaa aaatatcatt tgggtgtgag tccactttgc gatcgtcaca ctgaatctat   1680

tgccaacatc cagattggta actatacata tttagatata gctggttaga aaaatgccac   1740

tgtttttatc aagaagggaa atatatttga aatataaaat attaaaatta tgctcatttc   1800

tatttttaaa aataatttaa gaaattttac ccttgttttc ccttgttatg gctcttctaa   1860

ttctcattta attttaggat gtaaaaagta tatttttgca gaacaggcag cagcaataac   1920

ttgtttctgt tcttatgtaa ataagaatcc attattcgct catgtggaag cttcttttgc   1980

atcatttggg actgccattt aaaaaaggat aggtaaacaa agaaatgaca aaaataaaat   2040

aaataaaata aaaatggata ggtggtgacc cactgagcct gatcataata cgaagaccag   2100

cttctgccac tgcctttcca gactcttacc actgcctgtt gattaaatct aactcttcaa   2160

catcctagac aggcccttat aatcttgctt caaatgctgt gcagccatct tgcctcaact   2220

tccctctcat ttgcctacag catctcggga cgcttctgtg tttcccaagt atacgctgtt   2280

ctttcgctct ttgtgcctcg ccagtgcttt ccatgtgcct cgtagagtta tttttcttga   2340

agaggcagct caaatgtcac cttctccaga agctgctctc cacttgcttt aggcagagtc   2400

agtcactttt cttctagatt ccaaagtgcc tgatccactt ggttgtggat tcctggagcc   2460

tagcaccaca ccagaagcac gaggcccttg agaactgtgt gttgagtgaa ctaataactg   2520

tattatagaa agcataatga aaatgtcctg tgactgaagt atgtgtagct tgttgcagga   2580

gttcacagga aagttgacta ggattgagtg tgttgggctt tgggtataaa ggagggggat   2640

tctacggggg cagtagctca acaaggaata gagggaggag tgtaattttg gtagctggtg   2700

ttgaataggg cctttgagaa tcagactgaa cacagtgaaa tatgtgccca aagttcagaa   2760

agatgaagtt tccagaaact aagaaggtag cacaatatgt ggcatcatac tcagaaagga   2820

agaccatgcc atggggccag aaattcagaa acgtaattct tacattgtga ttgcaatgga   2880

tactcatgga agaaagtggg tagtggccga tttgacttca gagtgacagg tagagaaggg   2940

aagagcgtgt agaactgtgg ccagacttta ggagtgtgag ggatgctgaa tctcccagag   3000

agctcacact ggccaggaat gctgagagta gcagatgctt ttcttttggg aggatagtaa   3060

aacaatttag aaccagatat gctttgtctt gattctcaag tagaataatc ttcaaatgca   3120

aaagaataca ttagaaatgg acaaaagtgg ccaggagcgg tagctcatac ttgtaaccca   3180

gcactttggg aagccgaggc gggctgatcg cttgaggtca ggagttcgag accagcctgg   3240

ccaaaatagt gaaactcacg tttctactaa aaatacaaaa attagctggg tgtgatggcc   3300

acttgggagg ctgagatagg agaatcgctt gaacctggga ggcagaggtt gcagtgagcc   3360

aatatcgtgc cactgcattc cagcctgggt gacagaatga aactccatca ctccatctca   3420

aaaaaaaaaa aaaaaaaaaa tggacaaaag agaattgaat cgaagacagg tgaatcggta   3480

gtcaactcag ttacttttaa tattaaatgt ctttttatcc tagtaaacta ctcccttgct   3540

taatgggaga acttgcaaat gagatttaaa acattgtaat ttttataagg taacagaagc   3600

tagatccctt tcactgttca tctcaagcta ttgatcttgt cagtgttgta cagatctaga   3660

atgggttgtc agggataagg tcactgatct gatggtgatt gttgacatct gctgactcca   3720

cacaacaacc ctaggggacc ggtgctttga gcatccttat tttcagatgg tttgcccact   3780

tcatgcagtt aacagctgtt ggtgttgggc ttcaaatcca ggtctttcgg acatcaaatc   3840

ccagcctctt aacaactcac caagcagtga ttactactcc ccaacatagg ggcagtatgt   3900

acaagtcatg ttgaactaat acagtttctt tctttgatag gaatactaat tttgttgaac   3960

aagaaaatat gtactggata agagtaaggc atttgacaag gcgtcctgtg aaatctgtga   4020

agataaagta gaggcttgtg gggctagtac aattaaatgg agtcacaaat ggttgaacag   4080

ctgtgttcga ggtactaatt aacagagtcc tgccctccaa gagagaggct ggtccatggc   4140

tctggtctgt tcatttttat caggtattta aaacctaaaa gaaattt                 4187


<210>  5549
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  5549

Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro Val 
1               5                   10                  15


Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser Ser Ser 
            20                  25                  30


Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser Gln Arg Arg 
        35                  40                  45


Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala Leu Tyr Ile Arg 
    50                  55                  60


Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala Gly Phe Glu Ser Glu 
65                  70                  75                  80


Arg Arg Gly Ser His Pro Tyr Ile Asp Phe Arg Ile Phe His Ser Gln 
                85                  90                  95


Ser Glu Ile Glu Val Ser Val Ser Ala Arg Asn Ile Arg Arg Leu Leu 
            100                 105                 110


Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg Phe Phe Arg Gly Thr Ala 
        115                 120                 125


Val Ser Asn Ser Leu Asn Ile Leu Asp Asp Asp Tyr Asn Gly Gln Ala 
    130                 135                 140


Lys Cys Met Leu Glu Lys Val Gly Asn Trp Asn Phe Asp Ile Phe Leu 
145                 150                 155                 160


Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His 
                165                 170                 175


Leu Phe Ser Leu His Gly Leu Ile Glu Tyr Phe His Leu Asp Met Met 
            180                 185                 190


Lys Leu Arg Arg Phe Leu Val Met Ile Gln Glu Asp Tyr His Ser Gln 
        195                 200                 205


Asn Pro Tyr His Asn Ala Val His Ala Ala Asp Val Thr Gln Ala Met 
    210                 215                 220


His Cys Tyr Leu Lys Glu Pro Lys Leu Ala Asn Ser Val Thr Pro Trp 
225                 230                 235                 240


Asp Ile Leu Leu Ser Leu Ile Ala Ala Ala Thr His Asp Leu Asp His 
                245                 250                 255


Pro Gly Val Asn Gln Pro Phe Leu Ile Lys Thr Asn His Tyr Leu Ala 
            260                 265                 270


Thr Leu Tyr Lys Asn Thr Ser Val Leu Glu Asn His His Trp Arg Ser 
        275                 280                 285


Ala Val Gly Leu Leu Arg Glu Ser Gly Leu Phe Ser His Leu Pro Leu 
    290                 295                 300


Glu Ser Arg Gln Gln Met Glu Thr Gln Ile Gly Ala Leu Ile Leu Ala 
305                 310                 315                 320


Thr Asp Ile Ser Arg Gln Asn Glu Tyr Leu Ser Leu Phe Arg Ser His 
                325                 330                 335


Leu Asp Arg Gly Asp Leu Cys Leu Glu Asp Thr Arg His Arg His Leu 
            340                 345                 350


Val Leu Gln Met Ala Leu Lys Cys Ala Asp Ile Cys Asn Pro Cys Arg 
        355                 360                 365


Thr Trp Glu Leu Ser Lys Gln Trp Ser Glu Lys Val Thr Glu Glu Phe 
    370                 375                 380


Phe His Gln Gly Lys Tyr Arg Lys Lys Ile Ser Phe Gly Cys Glu Ser 
385                 390                 395                 400


Thr Leu Arg Ser Ser His 
                405


<210>  5550
<211>  442
<212>  DNA
<213>  Homo sapiens

<400>  5550
tcagaaagat gaagtttcca gaaactaaga aggtagcaca atatgtggca tcatactcag     60

aaaggaagac catgccatgg ggccagaaat tcagaaacgt aattcttaca ttgtgattgc    120

aatggatact catggaagaa agtgggtagt ggccgatttg acttcagagt gacaggtaga    180

gaagggaaga gcgtgtagaa ctgtggccag actttaggag tgtgagggat gctgaatctc    240

ccagagagct cacactggcc aggaatgctg agagtagcag atgcttttct tttgggagga    300

tagtaaaaca atttagaacc agatatgctt tgtcttgatt ctcaagtaga ataatcttca    360

aatgcaaaag aatacatgag ccaatatcgt gccactgcat tccagcctgg gtgacagaat    420

gaaactccat cactccatct ca                                             442


<210>  5551
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  5551

Met Lys Phe Pro Glu Thr Lys Lys Val Ala Gln Tyr Val Ala Ser Tyr 
1               5                   10                  15


Ser Glu Arg Lys Thr Met Pro Trp Gly Gln Lys Phe Arg Asn Val Ile 
            20                  25                  30


Leu Thr Leu 
        35


<210>  5552
<211>  4031
<212>  DNA
<213>  Homo sapiens

<400>  5552
aaaaaatcaa ctttattgtg gtagaactta catgcagtaa tacagtgcat acattttatg     60

tgtacggttt tgacaaatgt atactcccaa ccacccaact gttttttttt ctctaagaga    120

cagggtttca cagtgttgcc aggctggagt gcagtggcgt gatcatggct cactgcagcc    180

tcgacatcct gggctcaagc tggaggccag ctaatttttt aaattttttg tagagacagg    240

gtctcactct attgcccacc ccaattttta aattaaactt caaaaaaatc tctgggccaa    300

gactgcatcc tctgtttgag aatgttgtgg gagagattga tgagtaatca ccatacaatc    360

tggtaagtgg aaagatggta ataagttctc tgcagcacac aaaagggtta acctggtcag    420

cgaaggcttc tgcactccca tctccctctg ggcacaccca acccaagcca ggggcaggga    480

aatctgggtg atgccaggtg agcagggtgg ggatgcatgt ggacaaaaat taataaaaac    540

atgattttga acactttttg cctgtggagt tctgataata cttaaacact tttcatcctt    600

aacatactca gtgaacactt tacccaaggc ttcaattaag gatatagata aaatcacaaa    660

gccctacaat gcaggcattt cccttctccc ttatcatagt gaacatttta aaatggagtc    720

acccaggact gggcacggtg actcatgcct gtaataccag ctacttggga ggctgaggca    780

gaagaatcac ttaaacccgg gaggtggagg tttcggtgag ccgtgattgc gccattactc    840

tgcagcctgg gcaacaagag cgaaactcca tctcaaaaaa aaaaaaaaaa aaaaaaaaaa    900

gaagtgcgca acctggatcc ctcacatgca cagtttacaa tagggtttgt gctcctatga    960

gaagctactg cttccaaggc agagctcagg caataatgct cactggctgg cagctcacct   1020

cctgctgtgc acctggttcc tctcaggttc ctaacaggcc atggaccagt accggtccat   1080

ggcctgggga ttgaggagcc ctgcgaggac cgccttgtcc ttttgccttc tgtgtgtggg   1140

aggttcattt ctttcagtaa tttctcagga tggacataat gtgtcaagaa tctgtcttca   1200

ctaggcaggg catggtggct tatgcctgtg attccagcac tttgggaggc caaggcaggc   1260

ggatcacctg agattaggaa ttcgagacca gcctggccaa catggtgaaa ccccatctct   1320

ataaaagtac caaaaaaaaa aaaaagtcag gcatggtggt aggcgcctat aatcccagct   1380

gctcaggagc ctgagtaaga gaatcgattg aacctgggag gcagaggctg cagtgagccg   1440

agatcgcacc actgcactcc aggctgggca tcagcaagac tctgtcacaa aaaaatagaa   1500

tctgttttca gaggtagcat cattaggaaa aataaaaata caatactgat tcaggacatt   1560

ttatgtcact aaactgctct cctccatgat agtgccacct cctctttacc ctcagcaagc   1620

caccagtatc tcaggtacct tctttctgct atttctacta tatttttgat ttgccaattt   1680

agccaaaaaa aaaaaaaaaa aaaaaaagct accaccaacg aaactcactg tgataaccat   1740

tacaatggga aatgataagg gctggcaggc agtgaaaaca gtaagctttt cactgaacac   1800

agcaaaactc accacttaat agttttctat tttattgaaa aagaacccta atgatggctt   1860

tgcagataca agtaaaagct gaccttcaca tatgttaaat aatctgtagt ttcttttttg   1920

acatttcttt gttgtcagct cttaacagat gtaatcacag aatggaaata acatctgtct   1980

tttaatccac cttaaaaagt taagttattg aagtccttgt ctttgttata atattgaaaa   2040

ttttgtttct gatgaaaggt ttttttttac aagcagaaat gttacatttt tatatcaaat   2100

atttttttgc atgtgtgatt tgtttttaaa gttactttct cttcacagaa tttttgagaa   2160

ttcagttgct tattgtcatg ttcctatttt taatggttaa ctctttaata tacctgagaa   2220

tgttttgatg tcatgtgcag tcatacatta attttttaaa tcagtctaat tttggattat   2280

tgtattctcc caggatgtct attcttctgc caataagaat gtaacccctt tgcatactgc   2340

ctaataaatt acatgttcat aagacataga cacccatgcc cattcatgta tatgtcaagg   2400

aggggagatt gctttatatg cagtatgctt tatatcctat gcattctgtt catcttgatt   2460

agtaagcagc gctttagaat gctttatttt ttcaatgctt ttgtatatcc taaagaggaa   2520

ataattttct tcatcttctc ctattcattg accttctccg tgtactaatt atatgcgata   2580

caaaaataaa taatatgcat ctctgcttcc aggtagctta cagttttcca ggagattcaa   2640

gccctcagac agtgatttct ctgactgaga tgaacttaac acagggagta gaaagagatg   2700

attgattcgt tctagcagag aaagaaaaca atagaatttg aatctaaaat tatttttatc   2760

tcatttttaa aattttcagt ttttatcttt gttgtataac atataaatgt tagttcagta   2820

taataatcca taagtacata tacttaatat aagtggtgta tgctcaaaaa ttttcactgt   2880

tagagcacag gatcattaca gtttagtcag cactgtccta acgtaaacct aaataatacc   2940

atgctctgat gagtggtatt gtggcaggtc atgaggtgct gtgggaacac aaatctggcc   3000

aagtttgcca gaaaatgaga ggcatttcat gaaaagcaga tgatatagtc aaggtgatct   3060

tttttatcat tgaacatttg tcagctaatc ataaactttt atttattgtg attattaaat   3120

aagtttggta atgattattg agagtaaagt tacaatttct ggtgtgcaag attgctttcc   3180

ctgacatgaa tacattgtat cattgttatg aatgtagcca tccgttaggg gaggatttta   3240

tcacagactt gacatagact tccacttaac atgattactc agtagcctcc ttaaacatca   3300

ggactaaagg aataacctta catcttagat tacattattg aaatccaata accaatttgt   3360

tgataaataa acacccttaa aattttagat cttttgttca gtaatggcta cagtaataaa   3420

aatgtgccaa actatgtttg tcattttaaa gccattattt ctcaaaaaga acggtttatg   3480

ttttagctgc cattttaatt aagcttgtta aaaatgaaat ggcctaagga tgaactctgt   3540

aaactccaca tgggcagggc cactgttgta tcatggcttt gccagtgtgg tgatgagatc   3600

aggacctggc agatgtgctt ggtgaaccta atgaacaacc acctgaggaa tgacgtgaag   3660

ggggaggaga ttaccaccac taccattggc tgctaattca aaactactgt gatggcgtag   3720

agcttatttt agatatatct gtgattcatt attcttttgt cacacttcag cttgccaatt   3780

ctgtaactcc ttgggatatc ttgctgagct taattgcagc tgccactcat gatctggatc   3840

atccaggtgt taatcaacct ttccttatta aaactaacca ttacttggca actttataca   3900

aggttagtgc aattttatca tcaagattta ttatttttgc attctagaaa atctttcata   3960

ttttgaagaa atgaaagtaa tgaaaataaa ttctcaatga atgttagaat tttaaccaga   4020

ttaatattgc t                                                        4031


<210>  5553
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  5553

Met Gln Ala Phe Pro Phe Ser Leu Ile Ile Val Asn Ile Leu Lys Trp 
1               5                   10                  15


Ser His Pro Gly Leu Gly Thr Val Thr His Ala Cys Asn Thr Ser Tyr 
            20                  25                  30


Leu Gly Gly 
        35


<210>  5554
<211>  1089
<212>  DNA
<213>  Homo sapiens

<400>  5554
gagctggtcg ctgctcctga gtcccgcgcg ccctgggtct ggccgctggc tccagctgtc     60

ttttcttgca ctgctttgct ccgttcgtgc tgcgctcgaa ctctgcagtc cgggtacctg    120

ctcctctcgg ccgaggagcc ccagggcggc ggggttccct ttccgacttt gcctgtgctg    180

gccccgcttg caccccgtcc cccctcgcct ggagcgaggc gcgcgccggt cctggtaatt    240

ggcgccgcgg ccgccgcgga gccttcccgc cggcggcccg agcggagggc tggggttggg    300

gaggcgtgag cgcggcttcc cagcccgggg tcggtccccg cccgccctgc ccccgtctcg    360

gcccggagcc cccgagccgc ggccccctcc cactgcaggg gccggcggcc gcggcagggc    420

gggcgccgcg cggaggcagg gcgggcgtat tcaatggaag tgtgttacca gctgccggta    480

ctgcccctgg acaggccggt cccccagcac gtcctcagcc gccgaggagc catcagcttc    540

agctccagct ccgctctctt cggctgcccc aatccccggc agctctctca gaggcgtgga    600

gctatttcct atgacagttc tgatcagact gcattataca ttcgtatgct aggagatgta    660

cgtgtaagga gccgagcagg atttgaatca gaaagaagag gttctcaccc atatattgat    720

tttcgtattt tccactctca atctgaaatt gaagtgtctg tctctgcaag gaatatcaga    780

aggctactaa gtttccagcg atatcttaga tcttcacgct tttttcgtgg tactgcggtt    840

tcaaattccc taaacatttt agatgatgat tataatggac aagccaagtg tatgctggaa    900

aaagttggaa attggaattt tgatatcttt ctatttgata gactaacaaa tggaaatagt    960

ctagtaagct taacctttca tttatttagt cttcatggat taattgagta cttccattta   1020

gatatgatga aacttcgtag atttttaggt aagtgattct aacccattaa cagtaacaag   1080

atttacatt                                                           1089


<210>  5555
<211>  200
<212>  PRT
<213>  Homo sapiens

<400>  5555

Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro Val 
1               5                   10                  15


Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser Ser Ser 
            20                  25                  30


Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser Gln Arg Arg 
        35                  40                  45


Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala Leu Tyr Ile Arg 
    50                  55                  60


Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala Gly Phe Glu Ser Glu 
65                  70                  75                  80


Arg Arg Gly Ser His Pro Tyr Ile Asp Phe Arg Ile Phe His Ser Gln 
                85                  90                  95


Ser Glu Ile Glu Val Ser Val Ser Ala Arg Asn Ile Arg Arg Leu Leu 
            100                 105                 110


Ser Phe Gln Arg Tyr Leu Arg Ser Ser Arg Phe Phe Arg Gly Thr Ala 
        115                 120                 125


Val Ser Asn Ser Leu Asn Ile Leu Asp Asp Asp Tyr Asn Gly Gln Ala 
    130                 135                 140


Lys Cys Met Leu Glu Lys Val Gly Asn Trp Asn Phe Asp Ile Phe Leu 
145                 150                 155                 160


Phe Asp Arg Leu Thr Asn Gly Asn Ser Leu Val Ser Leu Thr Phe His 
                165                 170                 175


Leu Phe Ser Leu His Gly Leu Ile Glu Tyr Phe His Leu Asp Met Met 
            180                 185                 190


Lys Leu Arg Arg Phe Leu Gly Lys 
        195                 200


<210>  5556
<211>  608
<212>  DNA
<213>  Homo sapiens

<400>  5556
aaaagctgca tgcaagatac caactgagga ttataatacc aagacagaca cttcaatttc     60

agattgagct gaaataaaaa gaataaaaga aaagactcgt taaagtcaga acctgctgga    120

caagaaggcc tatggcaaat cctactgaag ataaatttat aagccttaag agaataagga    180

ctatgacaaa aacaatccaa accacaataa ttcatggtag gaaatattgt ggcatctaca    240

taataaaatg gttgaggtcc ttcttttgtt aattttgagg cctataattg ctccttaact    300

ggtcaggtat cttagatatc agctggctca caggagaatg tatcttcata atataaaccc    360

aaacgttgct tataataaac tgtacatata aaaaatctta aaagaaaagt tcaatattgc    420

aatatagatg tctaatttct aggtaaattt agtaaacaga atatgttcaa catggagaaa    480

atcacactcc agaaataagt taaaaatatt tcaacatcta aaaaaaaatt cagcagcacc    540

cacagataca gcacatagaa gaaattaaaa aattatgaat agttttaata aataacacta    600

atatcata                                                             608


<210>  5557
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  5557

Met Ala Asn Pro Thr Glu Asp Lys Phe Ile Ser Leu Lys Arg Ile Arg 
1               5                   10                  15


Thr Met Thr Lys Thr Ile Gln Thr Thr Ile Ile His Gly Arg Lys Tyr 
            20                  25                  30


Cys Gly Ile Tyr Ile Ile Lys Trp Leu Arg Ser Phe Phe Cys 
        35                  40                  45


<210>  5558
<211>  572
<212>  DNA
<213>  Homo sapiens

<400>  5558
agaagaaaaa ctcttagaag ccagcaactt ttacaagcac cctgggacat ttagttgagg     60

ggcttgagtg ttgtataaca caataatttt tagtcagaat aatgttaata gagcctgttt    120

ttaaaagttg aaagattcgt actgtttttt tgtttttaaa aagatttcca tgccaaagag    180

ttttaagtat tgatgctgaa ctgaaatgga caagcttgag ttacctggaa aattcattta    240

tgtggatgga acaccagctc ttccaaggat gccaatagaa gagagagatt atgcagcggg    300

cttttgattg atccaatggg aattacattg atctggtgtc tggccttggt tcttatcaag    360

tggatcacct ctaagaggcg tggagctatt tcctatgaca gttctgatca gactgcatta    420

tacattcgta tgctaggaga tgtacgtgta aggagccgag caggatttga atcagaaaga    480

agaggttctc acccatatat tgattttcgt attttccact ctcaatctga aattgaagtg    540

tctgtctctg caaggaatat cagaaggcta ct                                  572


<210>  5559
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  5559

Met Gly Ile Thr Leu Ile Trp Cys Leu Ala Leu Val Leu Ile Lys Trp 
1               5                   10                  15


Ile Thr Ser Lys Arg Arg Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln 
            20                  25                  30


Thr Ala Leu Tyr Ile Arg Met Leu Gly Asp Val Arg Val Arg Ser Arg 
        35                  40                  45


Ala Gly Phe Glu Ser Glu Arg Arg Gly Ser His Pro Tyr Ile Asp Phe 
    50                  55                  60


Arg Ile Phe His Ser Gln Ser Glu Ile Glu Val Ser Val Ser Ala Arg 
65                  70                  75                  80


Asn Ile Arg Arg 



<210>  5560
<211>  725
<212>  DNA
<213>  Homo sapiens

<400>  5560
ggaaaagcca gcagtgaccc cgcggtcagg gctgaggacg gcgactgcgc cgggtgcttt     60

gggtttctgg ggtcggcagg ccggaacgcc gcctctagcg cgggacgagc acaccccata    120

gcctaggcgc gctggaacgc acgaatttag cgctcggggg gatgccccga aacggtgggg    180

cctcgtgcgc acgcgccttg gctggcgagg agctagggaa gggagtcacg gcggggcgcg    240

aagggaactg cggatgagat agatggggga aaacgtttgt cgggaggcga ctccaacaga    300

gccccagggt gcagaacaca aggaaggcta ctgtcgccct cggccgcttg ccagtctccc    360

tgggcgctgc ggcggcgcgg ggcgctgggc ctgcggcgcg gcgtcgtgac gtcacggtgg    420

cggcagccgt ggttggcgca aggccggtcc cccagcacgt cctcagccgc cgaggagcca    480

tcagcttcag ctccagctcc gctctcttcg gctgccccaa tccccggcag ctctctcaga    540

ggcgtggagc tatttcctat gacagttctg atcagactgc attatacatt cgtatgctag    600

gagatgtacg tgtaaggagc cgagcaggat ttgaatcaga aagaagaggt tctcacccat    660

atattgattt tcgtattttc cactctcaat ctgaaattga agtgtctgtc tctgcaagga    720

atatc                                                                725


<210>  5561
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  5561

Met Leu Gly Asp Val Arg Val Arg Ser Arg Ala Gly Phe Glu Ser Glu 
1               5                   10                  15


Arg Arg Gly Ser His Pro Tyr Ile Asp Phe Arg Ile Phe His Ser Gln 
            20                  25                  30


Ser Glu Ile Glu Val Ser Val Ser Ala Arg Asn 
        35                  40


<210>  5562
<211>  872
<212>  DNA
<213>  Homo sapiens

<400>  5562
gagctggtcg ctgctcctga gtcccgcgcg ccctgggtct ggccgctggc tccagctgtc     60

ttttcttgca ctgctttgct ccgttcgtgc tgcgctcgaa ctctgcagtc cgggtacctg    120

ctcctctcgg ccgaggagcc ccagggcggc ggggttccct ttccgacttt gcctgtgctg    180

gccccgcttg caccccgtcc cccctcgcct ggagcgaggc gcgcgccggt cctggtaatt    240

ggcgccgcgg ccgccgcgga gccttcccgc cggcggcccg agcggagggc tggggttggg    300

gaggcgtgag cgcggcttcc cagcccgggg tcggtccccg cccgccctgc ccccgtctcg    360

gcccggagcc cccgagccgc ggccccctcc cactgcaggg gccggcggcc gcggcagggc    420

gggcgccgcg cggaggcagg gcgggcgtat tcaatggaag tgtgttacca gctgccggta    480

ctgcccctgg acaggccggt cccccagcac gtcctcagcc gccgaggagc catcagcttc    540

agctccagct ccgctctctt cggctgcccc aatccccggc agctctctca gaggcgtgga    600

gctatttcct atgacagttc tgatcagact gcattataca ttcgtatgct agcatgaagg    660

aatggccaca ggacaggtga ctagtcattg tgggatggaa ttatagtcga tgaagtgagc    720

cttggaggaa gtcatggtcc tactcagaga aacagagaga tgtacgtgta aggagccgag    780

caggatttga atcagaaaga agaggttctc acccatatat tgattttcgt attttccact    840

ctcaatctga aattgaagtg tctgtctctg ca                                  872


<210>  5563
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  5563

Met Glu Val Cys Tyr Gln Leu Pro Val Leu Pro Leu Asp Arg Pro Val 
1               5                   10                  15


Pro Gln His Val Leu Ser Arg Arg Gly Ala Ile Ser Phe Ser Ser Ser 
            20                  25                  30


Ser Ala Leu Phe Gly Cys Pro Asn Pro Arg Gln Leu Ser Gln Arg Arg 
        35                  40                  45


Gly Ala Ile Ser Tyr Asp Ser Ser Asp Gln Thr Ala Leu Tyr Ile Arg 
    50                  55                  60


Met Leu Ala 
65


<210>  5564
<211>  2451
<212>  DNA
<213>  Homo sapiens

<400>  5564
agcagcctcg gggagcagcc cgggctgttt gttccgtcac cggggaaagg aggtacacac     60

agtcgcgcgc gcacggacac acacacacac gcacgcacgc acacacaccg gtggcgagtt    120

cgagccccgc ggcccctgtc cgcccgcgtg cgcccctcga cacagctcgc ctcccgcccc    180

ctgattcctg ctgctgccgc ccagaggaga aaggaacctc tgcctcgaat ttccccactg    240

cgccgggcgc tgcggagagc ggcgagggtg ggcgcgaggc ggagaacgcg atgaatgagt    300

tctcccctcg cctcggagtt gtctgagttg gcggcgctgc gcccaggctt ccggctctca    360

gcgccccacg cgcgcgtggc tccccgggct gccacccacg cccgcggccg gggccgagcc    420

agccacgcag ggcagccgag gctccggagc tcctgtcccg gccccagtcc gggtaaaagg    480

agggttgtcc ccagcggagg cgcacagccg cgcgttctcc ctgcactctc ttcgcggtcc    540

catctgttcc ccatggcgtc tcatccgcaa acccggatcc aggcttacct ggagaagaac    600

aagatcggtc ccctgtttga ggaattaatg accaagttaa taactgagac acctgaccag    660

ccaatcccat ttctcattga ccatcttcag tctaaacaag ggaaccgtgg acaacttcaa    720

agaactttgt ctggatctgc agctctatgg gcagaaagtg aaaaatcaga atccaaagga    780

acaagaaggg atttcagaag ctatgataaa ccttggcaat taaatgcaaa gaagcctaaa    840

aaatcaaaaa gtgaccttgc tgtgtctaat atttctccac catcaccgga ctccaaatca    900

tgtaaggaag tctcttattc aaatgctatt caaagcatgt aagtttatgt tgttaagaaa    960

atgaagaaaa ggtattaatt gaagcccaac ttttcatctg atatttctgg cctttaatct   1020

tagtgaattt cacttttact ccgcatttac attgatcttc attcatacgt atgtatttgc   1080

ttgcttatat tctcaaacat gtgtaattca cttggaccct tttgagtata atattccttg   1140

aagaatataa actgcatgga gcgggtctct tgtttctcat agccaattgt agcattacat   1200

catattgaaa gcagtagcta cctatattta atgaagtatg taaaagcaaa ttaaatctct   1260

tagaatagaa gcaaagaaga tttctattca aaacatttca taaaatttct taaaaaatat   1320

ttcatctggg attttcctga agtcctactc attaatttgt gatggaagtc cctatattct   1380

cttcactact actgtaatat ctttgttttt atgttactac aaaggaatga ctgaggttgg   1440

gtattttata aagaaaaaag gtttatttgg cttacggttc tgcagactgt acaagaagca   1500

tgacactagc atctgcttct tgtgagagcc gcaggaagct tccactcatg gcagaaggtg   1560

aaggggtgca cgcatcatat ggcgagagga aggagaaaga gatagcagag ggaggtgcca   1620

ggctcttttt aacagtcaga tcttgtaaga accaacagag tgagaagtca ctccttacca   1680

tgaggacagc accaagccac tcatgaggga ttgaccccca taacccaaat accttccacc   1740

aggccccacc tccgatattg gtgatcaaat ttaccatgtg atttggagag gacaaatatc   1800

caagctatac cacctaagta tcccttctct ctcaatggcc tactgctttg gtagctactg   1860

ggattctcca gtgctctgct atccccacat atgtataaac atgtcaaaaa tctcaggagc   1920

ctctagcaaa tcacagctat tcttggaaga aaagagaact tgcaagctgt tcttcttata   1980

catcaattcc ttgtgcttgt tacagggtga gatgtttgat tttagtttca acagagaaag   2040

gagtaggcag aaaatattta tctttgtttg aaaatgtttg aaaaaccact atgtgctaac   2100

tggaatctgc atctgggtca tttgtgaaag caactaaatt taactttgtg agcagcttca   2160

tttacatagt ggtactcata aaaagtattg cattaaccac accaagttct tgtgagaatt   2220

atatgaagtg ttaacaactt aaaatgttct tcagaaattg tgattgtaac caaattgtcc   2280

tgcttcatca gtttggtata tagaattagg tcccaacatt ttaaaaaata tacaagttta   2340

aaatttgcat gtctttttta caacagtata gccagtaata tccagcacag tgcctgtttc   2400

aattaataaa tgctaaatga taaaaatgaa taaaggaaga aataaaaaat g            2451


<210>  5565
<211>  215
<212>  PRT
<213>  Homo sapiens

<400>  5565

Met Ser Ser Pro Leu Ala Ser Glu Leu Ser Glu Leu Ala Ala Leu Arg 
1               5                   10                  15


Pro Gly Phe Arg Leu Ser Ala Pro His Ala Arg Val Ala Pro Arg Ala 
            20                  25                  30


Ala Thr His Ala Arg Gly Arg Gly Arg Ala Ser His Ala Gly Gln Pro 
        35                  40                  45


Arg Leu Arg Ser Ser Cys Pro Gly Pro Ser Pro Gly Lys Arg Arg Val 
    50                  55                  60


Val Pro Ser Gly Gly Ala Gln Pro Arg Val Leu Pro Ala Leu Ser Ser 
65                  70                  75                  80


Arg Ser His Leu Phe Pro Met Ala Ser His Pro Gln Thr Arg Ile Gln 
                85                  90                  95


Ala Tyr Leu Glu Lys Asn Lys Ile Gly Pro Leu Phe Glu Glu Leu Met 
            100                 105                 110


Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu Ile 
        115                 120                 125


Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg Thr 
    130                 135                 140


Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu Ser 
145                 150                 155                 160


Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln Leu 
                165                 170                 175


Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser Asn 
            180                 185                 190


Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Cys Lys Glu Val Ser Tyr 
        195                 200                 205


Ser Asn Ala Ile Gln Ser Met 
    210                 215


<210>  5566
<211>  1087
<212>  DNA
<213>  Homo sapiens

<400>  5566
agcagcctcg gggagcagcc cgggctgttt gttccgtcac cggggaaagg aggtacacac     60

agtcgcgcgc gcacggacac acacacacac gcacgcacgc acacacaccg gtggcgagtt    120

cgagccccgc ggcccctgtc cgcccgcgtg cgcccctcga cacagctcgc ctcccgcccc    180

ctgattcctg ctgctgccgc ccagaggaga aaggaacctc tgcctcgaat ttccccactg    240

cgccgggcgc tgcggagagc ggcgagggtg ggcgcgaggc ggagaacgcg atgaatgagt    300

tctcccctcg cctcggagtt gtctgagttg gcggcgctgc gcccaggctt ccggctctca    360

gcgccccacg cgcgcgtggc tccccgggct gccacccacg cccgcggccg gggccgagcc    420

agccacgcag ggcagccgag gctccggagc tcctgtcccg gccccagtcc gggtaaaagg    480

agggttgtcc ccagcggagg cgcacagccg cgcgttctcc ctgcactctc ttcgcggtcc    540

catctgttcc ccatggcgtc tcatccgcaa acccggatcc aggcttacct ggagaagaac    600

aagatcggtc ccctgtttga ggaattaatg accaagttaa taactgagac acctgaccag    660

ccaatcccat ttctcattga ccatcttcag tctaaacaag ggaaccgtgg acaacttcaa    720

agaactttgt ctggatctgc agctctatgg gcagaaagtg aaaaatcaga atccaaagga    780

acaagaaggg atttcagaag ctatgataaa ccttggcaat taaatgcaaa gaagcctaaa    840

aaatcaaaaa gtgaccttgc tgtgtctaat atttctccac catcaccgga ctccaaatca    900

ttgccaaggt cagtagagca tccaaagtgg aactggagga ctaaaccaca aagccgtgat    960

tttgatgaat tgaatcacat ccttcaggag agcaagaagc tggggaaagc ccttgagaat   1020

ctctctcgaa gtaagttcat ttacttgatt ataattgaaa cagtgacatt taattcttct   1080

cttctga                                                             1087


<210>  5567
<211>  263
<212>  PRT
<213>  Homo sapiens

<400>  5567

Met Ser Ser Pro Leu Ala Ser Glu Leu Ser Glu Leu Ala Ala Leu Arg 
1               5                   10                  15


Pro Gly Phe Arg Leu Ser Ala Pro His Ala Arg Val Ala Pro Arg Ala 
            20                  25                  30


Ala Thr His Ala Arg Gly Arg Gly Arg Ala Ser His Ala Gly Gln Pro 
        35                  40                  45


Arg Leu Arg Ser Ser Cys Pro Gly Pro Ser Pro Gly Lys Arg Arg Val 
    50                  55                  60


Val Pro Ser Gly Gly Ala Gln Pro Arg Val Leu Pro Ala Leu Ser Ser 
65                  70                  75                  80


Arg Ser His Leu Phe Pro Met Ala Ser His Pro Gln Thr Arg Ile Gln 
                85                  90                  95


Ala Tyr Leu Glu Lys Asn Lys Ile Gly Pro Leu Phe Glu Glu Leu Met 
            100                 105                 110


Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu Ile 
        115                 120                 125


Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg Thr 
    130                 135                 140


Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu Ser 
145                 150                 155                 160


Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln Leu 
                165                 170                 175


Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser Asn 
            180                 185                 190


Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Leu Pro Arg Ser Val Glu 
        195                 200                 205


His Pro Lys Trp Asn Trp Arg Thr Lys Pro Gln Ser Arg Asp Phe Asp 
    210                 215                 220


Glu Leu Asn His Ile Leu Gln Glu Ser Lys Lys Leu Gly Lys Ala Leu 
225                 230                 235                 240


Glu Asn Leu Ser Arg Ser Lys Phe Ile Tyr Leu Ile Ile Ile Glu Thr 
                245                 250                 255


Val Thr Phe Asn Ser Ser Leu 
            260


<210>  5568
<211>  1072
<212>  DNA
<213>  Homo sapiens

<400>  5568
agcagcctcg gggagcagcc cgggctgttt gttccgtcac cggggaaagg aggtacacac     60

agtcgcgcgc gcacggacac acacacacac gcacgcacgc acacacaccg gtggcgagtt    120

cgagccccgc ggcccctgtc cgcccgcgtg cgcccctcga cacagctcgc ctcccgcccc    180

ctgattcctg ctgctgccgc ccagaggaga aaggaacctc tgcctcgaat ttccccactg    240

cgccgggcgc tgcggagagc ggcgagggtg ggcgcgaggc ggagaacgcg atgaatgagt    300

tctcccctcg cctcggagtt gtctgagttg gcggcgctgc gcccaggctt ccggctctca    360

gcgccccacg cgcgcgtggc tccccgggct gccacccacg cccgcggccg gggccgagcc    420

agccacgcag ggcagccgag gctccggagc tcctgtcccg gccccagtcc gggtaaaagg    480

agggttgtcc ccagcggagg cgcacagccg cgcgttctcc ctgcactctc ttcgcggtcc    540

catctgttcc ccatggcgtc tcatccgcaa acccggatcc aggcttacct ggagaagaac    600

aagatcggtc ccctgtttga ggaattaatg accaagttaa taactgagac acctgaccag    660

ccaatcccat ttctcattga ccatcttcag tctaaacaag ggaaccgtgg acaacttcaa    720

agaactttgt ctggatctgc agctctatgg gcagaaagtg aaaaatcaga atccaaagga    780

acaagaaggg atttcagaag ctatgataaa ccttggcaat taaatgcaaa gaagcctaaa    840

aaatcaaaaa gtgaccttgc tgtgtctaat atttctccac catcaccgga ctccaaatca    900

tgtattgcaa tttcagatga actcgataag gaaacagtga catttaattc ttctcttctg    960

aggccccgtg tgattggaga atggattggt agagaagaaa atgatgctga tcccctagct   1020

gctgaaatgc tacagcctcc aattccaaga agcaaaaatg accaatggga aa           1072


<210>  5569
<211>  258
<212>  PRT
<213>  Homo sapiens

<400>  5569

Met Ser Ser Pro Leu Ala Ser Glu Leu Ser Glu Leu Ala Ala Leu Arg 
1               5                   10                  15


Pro Gly Phe Arg Leu Ser Ala Pro His Ala Arg Val Ala Pro Arg Ala 
            20                  25                  30


Ala Thr His Ala Arg Gly Arg Gly Arg Ala Ser His Ala Gly Gln Pro 
        35                  40                  45


Arg Leu Arg Ser Ser Cys Pro Gly Pro Ser Pro Gly Lys Arg Arg Val 
    50                  55                  60


Val Pro Ser Gly Gly Ala Gln Pro Arg Val Leu Pro Ala Leu Ser Ser 
65                  70                  75                  80


Arg Ser His Leu Phe Pro Met Ala Ser His Pro Gln Thr Arg Ile Gln 
                85                  90                  95


Ala Tyr Leu Glu Lys Asn Lys Ile Gly Pro Leu Phe Glu Glu Leu Met 
            100                 105                 110


Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu Ile 
        115                 120                 125


Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg Thr 
    130                 135                 140


Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu Ser 
145                 150                 155                 160


Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln Leu 
                165                 170                 175


Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser Asn 
            180                 185                 190


Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Cys Ile Ala Ile Ser Asp 
        195                 200                 205


Glu Leu Asp Lys Glu Thr Val Thr Phe Asn Ser Ser Leu Leu Arg Pro 
    210                 215                 220


Arg Val Ile Gly Glu Trp Ile Gly Arg Glu Glu Asn Asp Ala Asp Pro 
225                 230                 235                 240


Leu Ala Ala Glu Met Leu Gln Pro Pro Ile Pro Arg Ser Lys Asn Asp 
                245                 250                 255


Gln Trp 



<210>  5570
<211>  4078
<212>  DNA
<213>  Homo sapiens

<400>  5570
agcagcctcg gggagcagcc cgggctgttt gttccgtcac cggggaaagg aggtacacac     60

agtcgcgcgc gcacggacac acacacacac gcacgcacgc acacacaccg gtggcgagtt    120

cgagccccgc ggcccctgtc cgcccgcgtg cgcccctcga cacagctcgc ctcccgcccc    180

ctgattcctg ctgctgccgc ccagaggaga aaggaacctc tgcctcgaat ttccccactg    240

cgccgggcgc tgcggagagc ggcgagggtg ggcgcgaggc ggagaacgcg atgaatgagt    300

tctcccctcg cctcggagtt gtctgagttg gcggcgctgc gcccaggctt ccggctctca    360

gcgccccacg cgcgcgtggc tccccgggct gccacccacg cccgcggccg gggccgagcc    420

agccacgcag ggcagccgag gctccggagc tcctgtcccg gccccagtcc gggtaaaagg    480

agggttgtcc ccagcggagg cgcacagccg cgcgttctcc ctgcactctc ttcgcggtcc    540

catctgttcc ccatggcgtc tcatccgcaa acccggatcc aggcttacct ggagaagaac    600

aagatcggtc ccctgtttga ggaattaatg accaagttaa taactgagac acctgaccag    660

ccaatcccat ttctcattga ccatcttcag tctaaacaag ggaaccgtgg acaacttcaa    720

agaactttgt ctggatctgc agctctatgg gcagaaagtg aaaaatcaga atccaaagga    780

acaagaaggg atttcagaag ctatgataaa ccttggcaat taaatgcaaa gaagcctaaa    840

aaatcaaaaa gtgaccttgc tgtgtctaat atttctccac catcaccgga ctccaaatca    900

ttgccaaggt cagtagagca tccaaagtgg aactggagga ctaaaccaca aagccgtgat    960

tttgatgaat tgaatcacat ccttcaggag agcaagaagc tggggaaagc ccttgagaat   1020

ctctctcgaa gtattgcaat ttcagatgaa ctcgataagg aaacagtgac atttaattct   1080

tctcttctga ggccccgtgt gattggagaa tggattggta gagaagaaaa tgatgctgat   1140

cccctagctg ctgaaatgct acagcctcca attccaagaa gcaaaaatga ccaatgggaa   1200

agtgaagata gtggctctag tcctgcagga agcttaaaga tggagcctaa gaacaaagga   1260

ttaaaacagc agcaacagca acataagaaa ctcctggccg caatgctctc tcaagattct   1320

tttgagtcca tccacagccc taccccatct gtaacagaag aagatattga taatgaagat   1380

gatgcaatgg aattgctggg taattttaaa aattaataat ttctcatttt cttctttgac   1440

attgtaaaaa aaacgtgtgg tgattaagag attttaaaag ttttgaatag ccttgtctta   1500

gggaaaagaa accatttagt acatatttta tttacattag actcacataa agttgcatgt   1560

aagaactaaa ttgaaatacc ctaagcatat gaatatttat tagactgtat tttgtgcttt   1620

gtgtatgctg cactttacct tctgactacg taatgaagcg ttattctgtg tgcaactgtg   1680

atcaaaattc aagtctgtct gctttattct ctgataataa ttgccttgtt tacatctatt   1740

gtctataaaa tatacccaaa gtacatattt cagccctcac tccaaaatgt ctacctttta   1800

ttttgaggat gctttagaaa aatagaataa agttgaaagg ggcagatagt aaattcaggt   1860

tttatgtttt ccgtaaatga cgggaaagtt tgcagagatt tcaaagtttc ttcaggcctg   1920

ttactttcat gaaaccttat taatcttgta tatgtaggat atctttttat attttttaat   1980

gtagtatatg tatgtttttg cttcatcaga aatctcttca tataaatttt taaactgaac   2040

ttctctttgg aacatcattt ttctgaagaa agaaaatgaa atgttatttc agagtgatcc   2100

acatataaaa caatgagttt tgaagtcagt ggtatcaatt attctgctac aaataaagag   2160

tatgattttc aaatacttta taacaatatg ctgttgtatt ttatttagaa agagaataaa   2220

taatataatt atttgaaagc cttaaacacg ttttacatat agaatatgga atctcagaaa   2280

aatataggcc attttctgaa gtttttgtta aaaatgagat tccttggttt taagtgttta   2340

tggcagtaaa atactatcat tataaaaaat gatatattgc ttatcatttt tgcataggcc   2400

tacaaaggtg ttatttggtc aatggtgaca ggtttgaaag atgttttctg atgctgtaaa   2460

aactgcattc atgctaacat taaggagatt gtatcatggc gttttcatta catgctgttg   2520

gtcccttcca attgggtctt ttcctcacct ccaaatcatt aacatggcag acgtgcccta   2580

tgtggcagtg gtagcttcat tcaacaaaca tttactgagc acttactcta tgctaagcac   2640

ttggctgggg tctgggaaca taaaaataaa atcattgtga tctgtgtttg aaggaatttt   2700

acattgtaat gttcaagata caatacgtca ctacctgtgc taactgcgct aattggatga   2760

agcacacagt tgtgtatagg ggtaacacct aaagcagagg taagggacag tgacccagga   2820

atgtttccta gagaagccga ttactctggc tagtcctgaa aagcaaatag atgtaagctc   2880

agcaggtggg gtgtggtcat tgtaggtttg ctcacgtagg tatgggctgt tttgcgattg   2940

tgctccataa ctatacctgt aaatggttcc tctgctttgg acagtaacag ggaaggggca   3000

actgagatcc agggtttctt tcaggagatg cagttgtcca ctccatgctg gtactcccta   3060

gatctcagct gccctgactg aaggttctag tctcccaagc tgaagaccga ggattgagtc   3120

ttggagacta tctaatgatg agcaattaat aactagtcct cattaattct ttttttagac   3180

attttagcct gtggtctgag caagtttaat aataagagat agttgaaggt ttggactttc   3240

ttcatgtaat tccacatatc tcagcacagg tggcaagcag tgtaataatg ttggtctcta   3300

ggtcatgaga ttatcctctt atagcttgga atgttacaag tccactggac tttatcttaa   3360

aataatgcca tattcaattt cttgtttttg aaatggattc cagcaaaatg tatgtgattg   3420

tgtctatttc agaaaaatat aaatgctaag ttcttggaaa tttatgtgaa atctaatttt   3480

atagagttta tatagaatca ttgtaagatg caatagagac atctggtatt taaaatcttt   3540

ttgaatctac attttgtaga tgtgtgtgct atagcttatg tgtttgtaaa tgtttaactt   3600

gtctttgtta tctataccaa gatataactg gctgaaaaat atttattatg catggaaagc   3660

actctgtaaa ccttgtgaag tgataaataa gtgaaaggta taattgttag ttgacattaa   3720

tataaaaaag gattattctt caataaaatt ggttgatttg aagggaaaaa atccttttag   3780

ttgaactagt agaagttagt aataactatt gactcttgtt ttgtttatta aggaaactag   3840

cattgttaat atatactgat taatatttaa ttattcacag ttgtttaatt atatatttgt   3900

ggatttcttt tctaaatgtt ttaggcatat gaaaatatta tagtacaaca cctgtaattt   3960

ttaagtagat caaatatttt ctgtaagatt gctttaaatg ctccttataa attcacattg   4020

caaaagtaac ttaatatgga attaacactt gtcagataat aaaacagcca aacttgtg     4078


<210>  5571
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  5571

Met Ser Ser Pro Leu Ala Ser Glu Leu Ser Glu Leu Ala Ala Leu Arg 
1               5                   10                  15


Pro Gly Phe Arg Leu Ser Ala Pro His Ala Arg Val Ala Pro Arg Ala 
            20                  25                  30


Ala Thr His Ala Arg Gly Arg Gly Arg Ala Ser His Ala Gly Gln Pro 
        35                  40                  45


Arg Leu Arg Ser Ser Cys Pro Gly Pro Ser Pro Gly Lys Arg Arg Val 
    50                  55                  60


Val Pro Ser Gly Gly Ala Gln Pro Arg Val Leu Pro Ala Leu Ser Ser 
65                  70                  75                  80


Arg Ser His Leu Phe Pro Met Ala Ser His Pro Gln Thr Arg Ile Gln 
                85                  90                  95


Ala Tyr Leu Glu Lys Asn Lys Ile Gly Pro Leu Phe Glu Glu Leu Met 
            100                 105                 110


Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu Ile 
        115                 120                 125


Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg Thr 
    130                 135                 140


Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu Ser 
145                 150                 155                 160


Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln Leu 
                165                 170                 175


Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser Asn 
            180                 185                 190


Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Leu Pro Arg Ser Val Glu 
        195                 200                 205


His Pro Lys Trp Asn Trp Arg Thr Lys Pro Gln Ser Arg Asp Phe Asp 
    210                 215                 220


Glu Leu Asn His Ile Leu Gln Glu Ser Lys Lys Leu Gly Lys Ala Leu 
225                 230                 235                 240


Glu Asn Leu Ser Arg Ser Ile Ala Ile Ser Asp Glu Leu Asp Lys Glu 
                245                 250                 255


Thr Val Thr Phe Asn Ser Ser Leu Leu Arg Pro Arg Val Ile Gly Glu 
            260                 265                 270


Trp Ile Gly Arg Glu Glu Asn Asp Ala Asp Pro Leu Ala Ala Glu Met 
        275                 280                 285


Leu Gln Pro Pro Ile Pro Arg Ser Lys Asn Asp Gln Trp Glu Ser Glu 
    290                 295                 300


Asp Ser Gly Ser Ser Pro Ala Gly Ser Leu Lys Met Glu Pro Lys Asn 
305                 310                 315                 320


Lys Gly Leu Lys Gln Gln Gln Gln Gln His Lys Lys Leu Leu Ala Ala 
                325                 330                 335


Met Leu Ser Gln Asp Ser Phe Glu Ser Ile His Ser Pro Thr Pro Ser 
            340                 345                 350


Val Thr Glu Glu Asp Ile Asp Asn Glu Asp Asp Ala Met Glu Leu Leu 
        355                 360                 365


Gly Asn Phe Lys Asn 
    370


<210>  5572
<211>  2688
<212>  DNA
<213>  Homo sapiens

<400>  5572
agcagcctcg gggagcagcc cgggctgttt gttccgtcac cggggaaagg aggtacacac     60

agtcgcgcgc gcacggacac acacacacac gcacgcacgc acacacaccg gtggcgagtt    120

cgagccccgc ggcccctgtc cgcccgcgtg cgcccctcga cacagctcgc ctcccgcccc    180

ctgattcctg ctgctgccgc ccagaggaga aaggaacctc tgcctcgaat ttccccactg    240

cgccgggcgc tgcggagagc ggcgagggtg ggcgcgaggc ggagaacgcg atgaatgagt    300

tctcccctcg cctcggagtt gtctgagttg gcggcgctgc gcccaggctt ccggctctca    360

gcgccccacg cgcgcgtggc tccccgggct gccacccacg cccgcggccg gggccgagcc    420

agccacgcag ggcagccgag gctccggagc tcctgtcccg gccccagtcc gggtaaaagg    480

agggttgtcc ccagcggagg cgcacagccg cgcgttctcc ctgcactctc ttcgcggtcc    540

catctgttcc ccatggcgtc tcatccgcaa acccggatcc aggcttacct ggagaagaac    600

aagatcggtc ccctgtttga ggaattaatg accaagttaa taactgagac acctgaccag    660

ccaatcccat ttctcattga ccatcttcag tctaaacaag ggaaccgtgg acaacttcaa    720

agaactttgt ctggatctgc agctctatgg gcagaaagtg aaaaatcaga atccaaagga    780

acaagaaggg atttcagaag ctatgataaa ccttggcaat taaatgcaaa gaagcctaaa    840

aaatcaaaaa gtgaccttgc tgtgtctaat atttctccac catcaccgga ctccaaatca    900

ttgccaaggt cagtagagca tccaaagtgg aactggagga ctaaaccaca aagccgtgat    960

tttgatgaat tgaatcacat ccttcaggag agcaagaagc tggggaaagc ccttgagaat   1020

ctctctcgaa gtattgcaat ttcagatgaa ctcgataagg aaacagtgac atttaattct   1080

tctcttctga ggccccgtgt gattggagaa tggattggta gagaagaaaa tgatgctgat   1140

cccctagctg ctgaaatgct acagcctcca attccaagaa gcaaaaatga ccaatgggaa   1200

agtgaagata gtggctctag tcctgcagga agcttaaaga tggagcctaa gaacaaagga   1260

ttaaaacagc agcaacagca acataagaaa ctcctggccg caatgctctc tcaagattct   1320

tttgagtcca tccacagccc taccccatct gtaacagaag aagatattga taatgaagat   1380

gatgcaatgg aattgctgga ggatcttaat gatttaagaa tggagggagt aacaaccctg   1440

gtaccttctg ggagcaaatt taaccaaggc cgtcctactt accctgctga gcctcaggcc   1500

aaggtcacac tgaacatctg ttcaaggtgt gccaggcttc aaggagacaa cctggaagaa   1560

aggacagaag agtcactacc aatactccat tctccagatg aaaaaatccc agattcattc   1620

gattccttgc ctgggactga agaagcacta atggaggagg gtgacgaatt tgagaaagca   1680

tctaaactaa caggacctgg agaagcctcc agtggagtag gacactcact gaaaaactac   1740

atggaagaag atgaatcctt aaagcaattg caggtagttc atcaaccatg gatcttgcca   1800

agtgacacag aaagtgaagg agtggaagca gaacaagaga aacgttccgc tgatcttctt   1860

ctttgcgttc catgctcttc ttgtcctacg ctggtctact ctggtttgtg aaacagagag   1920

aagaagttgc aagtggtcct taaagaaatg cagttattca aatccttatg tatagttcta   1980

attttattta ctatgtgtaa tcatttagag aatggttatt tttataatct caataataaa   2040

caagtactat cgtagccagg gggtgcccaa gtatgtaatc agagaacact aatcctggca   2100

aaggattgtg gggtggtcag gaggccggct gccttttgac atggttagag tcctgggttt   2160

agattacttt ataaatagtt attaagatta atatttgata tattaaatat tgcctgattc   2220

aaataacttt gcttaaaatt tttctgtatt ttaacttgtc tagggttttc tacttcttct   2280

atttttataa tattttctca ttttttagat tactaaacat tctacttatc cacatgtgcc   2340

aagatgtgcc atttaggtct ctgcagaaat tagctgtttg gtatcatcac ctgccataca   2400

tgttgtgtgc agcagtgaga agtatattct ctaccactgc tctttctcat gattattttc   2460

tctattccta ttaaaatgaa taattgatat gttaattaag taaagcaaat caataaggaa   2520

tgaaatgcat ggcccaaaac atagaaaatg aaaatcgttt gaccatttat ccaattattg   2580

aacccaatta agatgatcca ttttaaattt aatatatgct cgcttttgga atgtgttatg   2640

cattgatgtt aagtgaatgg atctaagtaa atctattgat atctctac                2688


<210>  5573
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  5573

Met Ser Ser Pro Leu Ala Ser Glu Leu Ser Glu Leu Ala Ala Leu Arg 
1               5                   10                  15


Pro Gly Phe Arg Leu Ser Ala Pro His Ala Arg Val Ala Pro Arg Ala 
            20                  25                  30


Ala Thr His Ala Arg Gly Arg Gly Arg Ala Ser His Ala Gly Gln Pro 
        35                  40                  45


Arg Leu Arg Ser Ser Cys Pro Gly Pro Ser Pro Gly Lys Arg Arg Val 
    50                  55                  60


Val Pro Ser Gly Gly Ala Gln Pro Arg Val Leu Pro Ala Leu Ser Ser 
65                  70                  75                  80


Arg Ser His Leu Phe Pro Met Ala Ser His Pro Gln Thr Arg Ile Gln 
                85                  90                  95


Ala Tyr Leu Glu Lys Asn Lys Ile Gly Pro Leu Phe Glu Glu Leu Met 
            100                 105                 110


Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu Ile 
        115                 120                 125


Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg Thr 
    130                 135                 140


Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu Ser 
145                 150                 155                 160


Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln Leu 
                165                 170                 175


Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser Asn 
            180                 185                 190


Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Leu Pro Arg Ser Val Glu 
        195                 200                 205


His Pro Lys Trp Asn Trp Arg Thr Lys Pro Gln Ser Arg Asp Phe Asp 
    210                 215                 220


Glu Leu Asn His Ile Leu Gln Glu Ser Lys Lys Leu Gly Lys Ala Leu 
225                 230                 235                 240


Glu Asn Leu Ser Arg Ser Ile Ala Ile Ser Asp Glu Leu Asp Lys Glu 
                245                 250                 255


Thr Val Thr Phe Asn Ser Ser Leu Leu Arg Pro Arg Val Ile Gly Glu 
            260                 265                 270


Trp Ile Gly Arg Glu Glu Asn Asp Ala Asp Pro Leu Ala Ala Glu Met 
        275                 280                 285


Leu Gln Pro Pro Ile Pro Arg Ser Lys Asn Asp Gln Trp Glu Ser Glu 
    290                 295                 300


Asp Ser Gly Ser Ser Pro Ala Gly Ser Leu Lys Met Glu Pro Lys Asn 
305                 310                 315                 320


Lys Gly Leu Lys Gln Gln Gln Gln Gln His Lys Lys Leu Leu Ala Ala 
                325                 330                 335


Met Leu Ser Gln Asp Ser Phe Glu Ser Ile His Ser Pro Thr Pro Ser 
            340                 345                 350


Val Thr Glu Glu Asp Ile Asp Asn Glu Asp Asp Ala Met Glu Leu Leu 
        355                 360                 365


Glu Asp Leu Asn Asp Leu Arg Met Glu Gly Val Thr Thr Leu Val Pro 
    370                 375                 380


Ser Gly Ser Lys Phe Asn Gln Gly Arg Pro Thr Tyr Pro Ala Glu Pro 
385                 390                 395                 400


Gln Ala Lys Val Thr Leu Asn Ile Cys Ser Arg Cys Ala Arg Leu Gln 
                405                 410                 415


Gly Asp Asn Leu Glu Glu Arg Thr Glu Glu Ser Leu Pro Ile Leu His 
            420                 425                 430


Ser Pro Asp Glu Lys Ile Pro Asp Ser Phe Asp Ser Leu Pro Gly Thr 
        435                 440                 445


Glu Glu Ala Leu Met Glu Glu Gly Asp Glu Phe Glu Lys Ala Ser Lys 
    450                 455                 460


Leu Thr Gly Pro Gly Glu Ala Ser Ser Gly Val Gly His Ser Leu Lys 
465                 470                 475                 480


Asn Tyr Met Glu Glu Asp Glu Ser Leu Lys Gln Leu Gln Val Val His 
                485                 490                 495


Gln Pro Trp Ile Leu Pro Ser Asp Thr Glu Ser Glu Gly Val Glu Ala 
            500                 505                 510


Glu Gln Glu Lys Arg Ser Ala Asp Leu Leu Leu Cys Val Pro Cys Ser 
        515                 520                 525


Ser Cys Pro Thr Leu Val Tyr Ser Gly Leu 
    530                 535


<210>  5574
<211>  3653
<212>  DNA
<213>  Homo sapiens

<400>  5574
gcccaggtaa agccatgttt tcctacactt aaaaatgtaa ataaatatcc cttagataat     60

ctggacagca gtttcttata tagcatgtct gagcactata ttttgctggg ctataaaagg    120

tttaattgtt gtttattggt acaataaggg attctagtta ctaatatcta cctgtagtca    180

ataaagcaaa cattgattgg ttgatcgaat cattgattca ttcaataggt attgattcag    240

caccagctat gagctaggca gagttctagg ccctacagag aaaactgata tcaaactaag    300

aaagtctttt tccaagtgct acagtagggg tgggggagga gagagataac aaactggtga    360

gcaaatgtta aacaaaatga ttctagagag tgctaaatac tgtgaggaag ataaaatgat    420

aaaataataa agacttctga agattggtta gggtaacctc ttgtagaagt atcattggag    480

accgaaggat gacacaccag ccatctgacc atgagagaac atcattcaag gcaaaggaaa    540

cagaccacca ccaacaaaaa aagatgcact ggggaatttc cagtaacact tttgttagct    600

ctcttaatat ctgatttttt gagcactaga acactgcctc tcacagaatc ctagcttaaa    660

acagcaatga acagactaga attctaggct aaaaccaaca agatgaaatg tgactgatat    720

gaatataaat ggtgcacata agttcacaaa cccaattaca cagcacaaaa tgatatccac    780

gtggcttgac agctgttcat attagaaaaa tctagggatt ctaatggact acatattgga    840

gattgctctt tgctgttcct gactggaaaa aaaaatatgt agatattacc cttgggcaga    900

tttcagccca acttaaagta tcattagagc tgtccaaaat ggaacagcct gctttgcaca    960

tagagaactc acattgctca actcaaaaaa gagcagaagg aaggaagaag gaaggacacg   1020

taacagggat ttttacaaaa acagaattcg gtatttcttg gagactactt taagacagtt   1080

tttggtttct gtaagtctgt gacttattac ttgttccttt aattccaata aaattttctt   1140

catttttgtt atttttaaaa cattaagaag aaaaaaatga tattgatata aggtagatgg   1200

tgaagtttag caaaagttta gtttataatg atatctctca aaatagcaaa ctgaagttta   1260

aaattcttaa gctataattt taaaggaatt tagattaaac ttttaatatg ttgttggcta   1320

agtataatac aaaataaaaa ctaaataaat cttggttttg ccacatatta gctgtgtaat   1380

atagacaatt tacttctctg ttattgtttc ctcagaatga gggcagtaac ttgtagccgt   1440

ctgaaaagat tgttataagc atggagttag ttgctgtata taaagcagtt agaccagtac   1500

ctgacaatat tacatgctaa gtaagtgctt gctattactg ttgctgttat tattaattat   1560

aattgtgtgc tctattctgc cttcaggaat taatgaccaa gttaataact gagacacctg   1620

accagccaat cccatttctc attgaccatc ttcagtctaa acaagggaac cgtggacaac   1680

ttcaaagaac tttgtctgga tctgcagctc tatgggcaga aagtgaaaaa tcagaatcca   1740

aaggaacaag aagggatttc agaagctatg ataaaccttg gcaattaaat gcaaagaagc   1800

ctaaaaaatc aaaaagtgac cttgctgtgt ctaatatttc tccaccatca ccggactcca   1860

aatcattgcc aaggtcagta gagcatccaa agtggaactg gaggactaaa ccacaaagcc   1920

gtgattttga tgaattgaat cacatccttc aggagagcaa gaagctgggg aaagcccttg   1980

agaatctctc tcgaagtatt gcaatttcag atgaactcga taaggaaaca gtgacattta   2040

attcttctct tctgaggccc cgtgtgattg gagaatggat tggtagagaa gaaaatgatg   2100

ctgatcccct agctgctgaa atgctacagc ctccaattcc aagaagcaaa aatgaccaat   2160

gggaaagtga agatagtggc tctagtcctg caggaagctt aaagatggag cctaagaaca   2220

aaggattaaa acagcagcaa cagcaacata agaaactcct ggccgcaatg ctctctcaag   2280

attcttttga gtccatccac agccctaccc catctgtaac agaagaagat attgataatg   2340

aagatgatgc aatggaattg ctggaggatc ttaatgattt aagaatggag ggagtaacaa   2400

ccctggtacc ttctgggagc aaatttaacc aaggccgtcc tacttaccct gctgagcctc   2460

aggccaaggt cacactgaac atctgttcaa ggtgtgccag gcttcaagga gacaacctgg   2520

aagaaaggac agaagagtca ctaccaatac tccattctcc agatgaaaaa atcccagatt   2580

cattcgattc cttgcctggg actgaagaag cactaatgga ggagggtgac gaatttgaga   2640

aagcatctaa actaacagga cctggagaag cctccagtgg agtaggacac tcactgaaaa   2700

actacatgga agaagatgaa tccttaaagc aattgcaggt agttcatcaa ccatggatct   2760

tgccaagtga cacagaaagt gaaggagtgg aagcagaaca agagaaacgt tccgctgatc   2820

ttcttctttg cgttccatgc tcttcttgtc ctacgctggt ctactctggt ttgtgaaaca   2880

gagagaagaa gttgcaagtg gtccttaaag aaatgcagtt attcaaatcc ttatgtatag   2940

ttctaatttt atttactatg tgtaatcatt tagagaatgg ttatttttat aatctcaata   3000

ataaacaagt actatcgtag ccagggggtg cccaagtatg taatcagaga acactaatcc   3060

tggcaaagga ttgtggggtg gtcaggaggc cggctgcctt ttgacatggt tagagtcctg   3120

ggtttagatt actttataaa tagttattaa gattaatatt tgatatatta aatattgcct   3180

gattcaaata actttgctta aaatttttct gtattttaac ttgtctaggg ttttctactt   3240

cttctatttt tataatattt tctcattttt tagattacta aacattctac ttatccacat   3300

gtgccaagat gtgccattta ggtctctgca gaaattagct gtttggtatc atcacctgcc   3360

atacatgttg tgtgcagcag tgagaagtat attctctacc actgctcttt ctcatgatta   3420

ttttctctat tcctattaaa atgaataatt gatatgttaa ttaagtaaag caaatcaata   3480

aggaatgaaa tgcatggccc aaaacataga aaatgaaaat cgtttgacca tttatccaat   3540

tattgaaccc aattaagatg atccatttta aatttaatat atgctcgctt ttggaatgtg   3600

ttatgcattg atgttaagtg aatggatcta agtaaatcta ttgatatctc tac          3653


<210>  5575
<211>  427
<212>  PRT
<213>  Homo sapiens

<400>  5575

Met Thr Lys Leu Ile Thr Glu Thr Pro Asp Gln Pro Ile Pro Phe Leu 
1               5                   10                  15


Ile Asp His Leu Gln Ser Lys Gln Gly Asn Arg Gly Gln Leu Gln Arg 
            20                  25                  30


Thr Leu Ser Gly Ser Ala Ala Leu Trp Ala Glu Ser Glu Lys Ser Glu 
        35                  40                  45


Ser Lys Gly Thr Arg Arg Asp Phe Arg Ser Tyr Asp Lys Pro Trp Gln 
    50                  55                  60


Leu Asn Ala Lys Lys Pro Lys Lys Ser Lys Ser Asp Leu Ala Val Ser 
65                  70                  75                  80


Asn Ile Ser Pro Pro Ser Pro Asp Ser Lys Ser Leu Pro Arg Ser Val 
                85                  90                  95


Glu His Pro Lys Trp Asn Trp Arg Thr Lys Pro Gln Ser Arg Asp Phe 
            100                 105                 110


Asp Glu Leu Asn His Ile Leu Gln Glu Ser Lys Lys Leu Gly Lys Ala 
        115                 120                 125


Leu Glu Asn Leu Ser Arg Ser Ile Ala Ile Ser Asp Glu Leu Asp Lys 
    130                 135                 140


Glu Thr Val Thr Phe Asn Ser Ser Leu Leu Arg Pro Arg Val Ile Gly 
145                 150                 155                 160


Glu Trp Ile Gly Arg Glu Glu Asn Asp Ala Asp Pro Leu Ala Ala Glu 
                165                 170                 175


Met Leu Gln Pro Pro Ile Pro Arg Ser Lys Asn Asp Gln Trp Glu Ser 
            180                 185                 190


Glu Asp Ser Gly Ser Ser Pro Ala Gly Ser Leu Lys Met Glu Pro Lys 
        195                 200                 205


Asn Lys Gly Leu Lys Gln Gln Gln Gln Gln His Lys Lys Leu Leu Ala 
    210                 215                 220


Ala Met Leu Ser Gln Asp Ser Phe Glu Ser Ile His Ser Pro Thr Pro 
225                 230                 235                 240


Ser Val Thr Glu Glu Asp Ile Asp Asn Glu Asp Asp Ala Met Glu Leu 
                245                 250                 255


Leu Glu Asp Leu Asn Asp Leu Arg Met Glu Gly Val Thr Thr Leu Val 
            260                 265                 270


Pro Ser Gly Ser Lys Phe Asn Gln Gly Arg Pro Thr Tyr Pro Ala Glu 
        275                 280                 285


Pro Gln Ala Lys Val Thr Leu Asn Ile Cys Ser Arg Cys Ala Arg Leu 
    290                 295                 300


Gln Gly Asp Asn Leu Glu Glu Arg Thr Glu Glu Ser Leu Pro Ile Leu 
305                 310                 315                 320


His Ser Pro Asp Glu Lys Ile Pro Asp Ser Phe Asp Ser Leu Pro Gly 
                325                 330                 335


Thr Glu Glu Ala Leu Met Glu Glu Gly Asp Glu Phe Glu Lys Ala Ser 
            340                 345                 350


Lys Leu Thr Gly Pro Gly Glu Ala Ser Ser Gly Val Gly His Ser Leu 
        355                 360                 365


Lys Asn Tyr Met Glu Glu Asp Glu Ser Leu Lys Gln Leu Gln Val Val 
    370                 375                 380


His Gln Pro Trp Ile Leu Pro Ser Asp Thr Glu Ser Glu Gly Val Glu 
385                 390                 395                 400


Ala Glu Gln Glu Lys Arg Ser Ala Asp Leu Leu Leu Cys Val Pro Cys 
                405                 410                 415


Ser Ser Cys Pro Thr Leu Val Tyr Ser Gly Leu 
            420                 425


<210>  5576
<211>  3268
<212>  DNA
<213>  Homo sapiens

<400>  5576
gggggcgggg agcccgaggg gtggaagccg gcggcggccg agcggggtca gttctctgta     60

gtgtttgcca atgttggagc cgtctgcaaa gtgtccccgg caagaagagg ctgcctacca    120

caaggacttt agcttacttt ttaaagattg aagaaaaaaa agaagacaga aaaagaagaa    180

ctcaaagata cacaaagtaa tttgaaccaa ggctcagaag tttttggagc cgtgagggat    240

acagcagttt ggtcaatatt gtcttaacat gcttcaaata aatcagatgt tctcagtgca    300

gctgagtctt ggtgagcaga catgggaatc cgaaggcagc agtataaaga aggctcagca    360

ggctgttgcc aataaagctt tgactgaatc tacgcttccc aaaccagttc agaagccacc    420

caaaagtaat gttaacaata acccaggcag tataactcca actgtggaac tgaatgggct    480

tgctatgaaa aggggagagc ctgccatcta caggccatta gatccaaagc cattcccaaa    540

ttatagagct aattacaact ttcggggcat gtacaatcag aggtatcatt gcccagtgcc    600

taagatcttt tatgttcagc tcactgtagg aaataatgaa ttttttgggg aaggaaagac    660

tcgacaagct gctagacaca atgctgcaat gaaagccctc caagcactgc agaatgaacc    720

tattccagaa agatctcctc agaatggtga atcaggaaag gatgtggatg atgacaaaga    780

tgcaaataag tctgagatca gcttagtgtt tgaaattgct ctgaagcgaa atatgcctgt    840

cagttttgag gttattaaag aaagtggacc accacatatg aaaagctttg ttactcgagt    900

gtcagtagga gagttctctg cagaaggaga aggaaatagc aaaaaactct ccaagaagcg    960

cgctgcgacc accgtcttac aggagcttaa aaaacttcca cctcttcctg tggtggaaaa   1020

gccaaaacta ttttttaaaa aacgccctaa aacaatagta aaggccggac cagaatatgg   1080

ccaagggatg aaccctatta gccgcctggc gcaaattcaa caggccaaaa aggaaaagga   1140

gccggattat gttttgcttt cagaaagagg aatgcctcga cgtcgagaat ttgtgatgca   1200

ggtgaaggta ggcaatgaag ttgctacagg aacaggacct aataaaaaga tagccaaaaa   1260

aaatgctgca gaagcaatgc tgttacaact tggttataaa gcatccacta atcttcagga   1320

tcaacttgag aagacagggg aaaacaaagg atggagtggt ccaaagcctg ggtttcctga   1380

accaacaaat aatactccaa aaggaattct tcatttgtct cctgatgttt atcaagagat   1440

ggaagccagc cgccacaaag taatctctgg cactactcta ggctatttgt cacccaaaga   1500

tatgaaccaa ccttcaagct ctttcttcag tatatctccc acatcgaata gttcagctac   1560

aattgccagg gaactcctta tgaatggaac atcttctaca gctgaagcca taggtttaaa   1620

aggaagttct cctactcccc cttgttctcc agtacaacct tcaaaacaac tggaatattt   1680

agcaaggatt caaggctttc aggcagcctt aagtgccttg aaacaatttt ctgaacaagg   1740

actggatcca atcgatggag caatgaatat cgaaaaaggt tctcttgaaa aacaagccaa   1800

gcatctgaga gagaaagcgg acaataacca ggcacccccg ggctccatcg ctcaggactg   1860

caagaaatca aactcggccg tctagcagct cccagaaccc gcggctgcca ccgcatcctt   1920

ataaacctgt cagcacgcat gagggtgtct gtgttcaggg aaatgaatga ctaataccat   1980

tatttgagtc ttatgtgaag acaacactat tctaacacga gagataatat acatggtact   2040

gtttattcaa ctggggaaaa ataaaacttt gagcatttcc cttggaactc gagatcagat   2100

cataactcat ttgcctagag gcagcagaaa tctgatcctg ctactggagc ttaaaataac   2160

aagtaaagaa aagtgttaga aacaaagcta aaattttaac atgattaata atagagaagt   2220

tgggtttggt tctgttgtta tgattgtttt gtcgtggtgc ttgtgttcag ttatattctc   2280

tctctctctc atttcaaata ctgcttgaca attcgaaaat gaaccaatga tgtgctgtgg   2340

aatgtgatgg ttgtcttcat atagagtcac atggtttctc tttttatgca gatatttata   2400

atcttcatcc tatatcagta ggaataacta taaggtgcac tacaaaaaga tgtatgcaaa   2460

caaacatgtt ttaaatcagg tcagatatct gatgaaaaat acgaactaat gttaagagca   2520

agtagtttca acatactcca ggaactgaga aacaaaacaa agcaattgtg ggttttgagc   2580

tccatatact cttagcaagt aagggggcgt cttgccccta tatatcatct tcccggattc   2640

cactccctgt tgtgggaatc gcgcccaccc ccatccgtgt gttgtagcca ctcacggttt   2700

gcatcaagag tgttttttgt aactgcctct ggacttggga cagtgagtag gatcaaaaat   2760

aaataatgta catgacgggg aagggaaaaa cctgttggag ttgcttccag ccagccacgc   2820

tccgggccag catgttggaa tccagcgtgg agcagatgca gtaaaaatgt ggttggtttc   2880

tgtgtgaagc gctgttgttg ttcttttgtt ctctcactct catcttttaa atatcacctc   2940

cgtgaaaccc atccgaaagg ccaccacccg gcctagtcac tgcccagcag tgggattaga   3000

gaatggatag gctgtacctg agaaactgca gagccgcctc ctgggtgact cgggccgggt   3060

tcctggccaa cgtcatcgca ttgttcaggc tttctcctta ttgatttgca aacattgtgc   3120

aatgagaaaa cactacatgg tctaactgct cgacccaaca tgacaatagg aatataatta   3180

tgtaagattt cacaagcaaa accaccacaa atcatgatct ggctgactca cacgcgactg   3240

gagaataaac aaacagcaac ataaggaa                                      3268


<210>  5577
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  5577

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
465                 470                 475                 480


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
                485                 490                 495


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
            500                 505                 510


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
        515                 520                 525


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
    530                 535


<210>  5578
<211>  3442
<212>  DNA
<213>  Homo sapiens

<400>  5578
gcggcgggag cgccggggag gcgggcggag gcgggcggag gcggggggcg gggagcccga     60

ggggtggaag ccggcggcgg ccgagcgggg tcagttctct gtagtgtttg ccaatgttgg    120

agccgtctgc aaagtgtccc cggcaagaag aggctgccta ccacaaggac tttagcttac    180

tttttaaaga ttgaagaaaa aaaagaagac agaaaaagaa gaactcaaag atacacaaag    240

taatttgaac caaggctcag aagtttttgg agccgtgagg gatacagcag tttggtcaat    300

attgtcttaa catgcttcaa ataaatcagc ttctctccaa gataaaatgg caaacccaaa    360

agagaaaact gcaatgtgtc tggtaaatga gttagcccgt ttcaatagag tccaacccca    420

gtataaactt ctgaatgaaa gagggcctgc tcattcaaag atgttctcag tgcagctgag    480

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    540

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    600

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    660

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    720

agctaattac aactttcggg gcatgtacaa tcagaggtat cattgcccag tgcctaagat    780

cttttatgtt cagctcactg taggaaataa tgaatttttt ggggaaggaa agactcgaca    840

agctgctaga cacaatgctg caatgaaagc cctccaagca ctgcagaatg aacctattcc    900

agaaagatct cctcagaatg gtgaatcagg aaaggatgtg gatgatgaca aagatgcaaa    960

taagtctgag atcagcttag tgtttgaaat tgctctgaag cgaaatatgc ctgtcagttt   1020

tgaggttatt aaagaaagtg gaccaccaca tatgaaaagc tttgttactc gagtgtcagt   1080

aggagagttc tctgcagaag gagaaggaaa tagcaaaaaa ctctccaaga agcgcgctgc   1140

gaccaccgtc ttacaggagc ttaaaaaact tccacctctt cctgtggtgg aaaagccaaa   1200

actatttttt aaaaaacgcc ctaaaacaat agtaaaggcc ggaccagaat atggccaagg   1260

gatgaaccct attagccgcc tggcgcaaat tcaacaggcc aaaaaggaaa aggagccgga   1320

ttatgttttg ctttcagaaa gaggaatgcc tcgacgtcga gaatttgtga tgcaggtgaa   1380

ggtaggcaat gaagttgcta caggaacagg acctaataaa aagatagcca aaaaaaatgc   1440

tgcagaagca atgctgttac aacttggtta taaagcatcc actaatcttc aggatcaact   1500

tgagaagaca ggggaaaaca aaggatggag tggtccaaag cctgggtttc ctgaaccaac   1560

aaataatact ccaaaaggaa ttcttcattt gtctcctgat gtttatcaag agatggaagc   1620

cagccgccac aaagtaatct ctggcactac tctaggctat ttgtcaccca aagatatgaa   1680

ccaaccttca agctctttct tcagtatatc tcccacatcg aatagttcag ctacaattgc   1740

cagggaactc cttatgaatg gaacatcttc tacagctgaa gccataggtt taaaaggaag   1800

ttctcctact cccccttgtt ctccagtaca accttcaaaa caactggaat atttagcaag   1860

gattcaaggc tttcaggcag ccttaagtgc cttgaaacaa ttttctgaac aaggactgga   1920

tccaatcgat ggagcaatga atatcgaaaa aggttctctt gaaaaacaag ccaagcatct   1980

gagagagaaa gcggacaata accaggcacc cccgggctcc atcgctcagg actgcaagaa   2040

atcaaactcg gccgtctagc agctcccaga acccgcggct gccaccgcat ccttataaac   2100

ctgtcagcac gcatgagggt gtctgtgttc agggaaatga atgactaata ccattatttg   2160

agtcttatgt gaagacaaca ctattctaac acgagagata atatacatgg tactgtttat   2220

tcaactgggg aaaaataaaa ctttgagcat ttcccttgga actcgagatc agatcataac   2280

tcatttgcct agaggcagca gaaatctgat cctgctactg gagcttaaaa taacaagtaa   2340

agaaaagtgt tagaaacaaa gctaaaattt taacatgatt aataatagag aagttgggtt   2400

tggttctgtt gttatgattg ttttgtcgtg gtgcttgtgt tcagttatat tctctctctc   2460

tctcatttca aatactgctt gacaattcga aaatgaacca atgatgtgct gtggaatgtg   2520

atggttgtct tcatatagag tcacatggtt tctcttttta tgcagatatt tataatcttc   2580

atcctatatc agtaggaata actataaggt gcactacaaa aagatgtatg caaacaaaca   2640

tgttttaaat caggtcagat atctgatgaa aaatacgaac taatgttaag agcaagtagt   2700

ttcaacatac tccaggaact gagaaacaaa acaaagcaat tgtgggtttt gagctccata   2760

tactcttagc aagtaagggg gcgtcttgcc cctatatatc atcttcccgg attccactcc   2820

ctgttgtggg aatcgcgccc acccccatcc gtgtgttgta gccactcacg gtttgcatca   2880

agagtgtttt ttgtaactgc ctctggactt gggacagtga gtaggatcaa aaataaataa   2940

tgtacatgac ggggaaggga aaaacctgtt ggagttgctt ccagccagcc acgctccggg   3000

ccagcatgtt ggaatccagc gtggagcaga tgcagtaaaa atgtggttgg tttctgtgtg   3060

aagcgctgtt gttgttcttt tgttctctca ctctcatctt ttaaatatca cctccgtgaa   3120

acccatccga aaggccacca cccggcctag tcactgccca gcagtgggat tagagaatgg   3180

ataggctgta cctgagaaac tgcagagccg cctcctgggt gactcgggcc gggttcctgg   3240

ccaacgtcat cgcattgttc aggctttctc cttattgatt tgcaaacatt gtgcaatgag   3300

aaaacactac atggtctaac tgctcgaccc aacatgacaa taggaatata attatgtaag   3360

atttcacaag caaaaccacc acaaatcatg atctggctga ctcacacgcg actggagaat   3420

aaacaaacag caacataagg aa                                            3442


<210>  5579
<211>  570
<212>  PRT
<213>  Homo sapiens

<400>  5579

Met Ala Asn Pro Lys Glu Lys Thr Ala Met Cys Leu Val Asn Glu Leu 
1               5                   10                  15


Ala Arg Phe Asn Arg Val Gln Pro Gln Tyr Lys Leu Leu Asn Glu Arg 
            20                  25                  30


Gly Pro Ala His Ser Lys Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
        35                  40                  45


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
    50                  55                  60


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
65                  70                  75                  80


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
                85                  90                  95


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
            100                 105                 110


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
        115                 120                 125


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
    130                 135                 140


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
145                 150                 155                 160


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
                165                 170                 175


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
            180                 185                 190


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
        195                 200                 205


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
    210                 215                 220


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
225                 230                 235                 240


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
                245                 250                 255


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
            260                 265                 270


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
        275                 280                 285


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
    290                 295                 300


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
305                 310                 315                 320


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
                325                 330                 335


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
            340                 345                 350


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
        355                 360                 365


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
    370                 375                 380


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
385                 390                 395                 400


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
                405                 410                 415


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
            420                 425                 430


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
        435                 440                 445


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
    450                 455                 460


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
465                 470                 475                 480


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
                485                 490                 495


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
            500                 505                 510


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
        515                 520                 525


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
    530                 535                 540


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
545                 550                 555                 560


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
                565                 570


<210>  5580
<211>  2886
<212>  DNA
<213>  Homo sapiens

<400>  5580
gggggcgggg agcccgaggg gtggaagccg gcggcggccg agcggggtca gttctctgta     60

gtgtttgcca atgttggagc cgtctgcaaa gtgtccccgg caagaagagg ctgcctacca    120

caaggacttt agcttacttt ttaaagattg aagaaaaaaa agaagacaga aaaagaagaa    180

ctcaaagata cacaaagtaa tttgaaccaa ggctcagaag tttttggagc cgtgagggat    240

acagcagttt ggtcaatatt gtcttaacat gcttcaaata aatcagatgt tctcagtgca    300

gctgagtctt ggtgagcaga catgggaatc cgaaggcagc agtataaaga aggctcagca    360

ggctgttgcc aataaagctt tgactgaatc tacgcttccc aaaccagttc agaagccacc    420

caaaagtaat gttaacaata acccaggcag tataactcca actgtggaac tgaatgggct    480

tgctatgaaa aggggagagc ctgccatcta caggccatta gatccaaagc cattcccaaa    540

ttatagagct aattacaact ttcggggcat gtacaatcag aggtatcatt gcccagtgcc    600

taagatcttt tatgttcagc tcactgtagg aaataatgaa ttttttgggg aaggaaagac    660

tcgacaagct gctagacaca atgctgcaat gaaagccctc caagcactgc agaatgaacc    720

tattccagaa agatctcctc agaatggtga atcaggaaag gatgtggatg atgacaaaga    780

tgcaaataag tctgagatca gcttagtgtt tgaaattgct ctgaagcgaa atatgcctgt    840

cagttttgag gttattaaag aaagtggacc accacatatg aaaagctttg ttactcgagt    900

gtcagtagga gagttctctg cagaaggaga aggaaatagc aaaaaactct ccaagaagcg    960

cgctgcgacc accgtcttac aggagcttaa aaaacttcca cctcttcctg tggtggaaaa   1020

gccaaaacta ttttttaaaa aacgccctaa aacaatagta aaggccggac cagaatatgg   1080

ccaagggatg aaccctatta gccgcctggc gcaaattcaa caggccaaaa aggaaaagga   1140

gccggattat gttttgcttt cagaaagagg aatgcctcga cgtcgagaat ttgtgatgca   1200

ggtgaaggta ggcaatgaag ttgctacagg aacaggacct aataaaaaga tagccaaaaa   1260

aaatgctgca gaagcaatgc tgttacaact tggttataaa gcatccacta atcttcagga   1320

tcaacttgag aagacagggg aaaacaaagg atggagtggt ccaaagcctg ggtttcctga   1380

accaacaaat aatactccaa aaggaattct tcatttgtct cctgatgttt atcaagagat   1440

ggaagccagc cgccacaaag taatctctgg cactactcta ggctatttgt cacccaaaga   1500

tatgaaccaa ccttcaagct ctttcttcag tatatctccc acatcgaata gttcagctac   1560

aattgccagg gaactcctta tgaatggaac atcttctaca gctgaagcca taggtttaaa   1620

aggaagttct cctactcccc cttgttctcc agtacaacct tcaaaacaac tggaatattt   1680

agcaaggatt caaggctttc aggcagcctt aagtgccttg aaacaatttt ctgaacaagg   1740

actggatcca atcgatggag caatgaatat cgaaaaaggt tctcttgaaa aacaagccaa   1800

gcatctgaga gagaaagcgg acaataacca ggcacccccg ggctccatcg ctcaggactg   1860

caagaaatca aactcggccg tctagcagct cccagaaccc gcggctgcca ccgcatcctt   1920

ataaacctgt cagcacgcat gagggtgtct gtgttcaggg aaatgaatga ctaataccat   1980

tatttgagtc ttatgtgaag acaacactat tctaacacga gagataatat acatggtact   2040

gtttattcaa ctggggaaaa ataaaacttt gagcatttcc cttggaactc gagatcagat   2100

cataactcat ttgcctagag gcagcagaaa tctgatcctg ctactggagc ttaaaataac   2160

aagtaaagaa aagtgttaga aacaaagcta aaattttaac atgattaata atagagaagt   2220

tgggtttggt tctgttgtta tgattgtttt gtcgtggtgc ttgtgttcag ttatattctc   2280

tctctctctc atttcaaata ctgcttgaca attcgaaaat gaaccaatga tgtgctgtgg   2340

aatgtgatgg ttgtcttcat atagagtcac atggtttctc tttttatgca gatatttata   2400

atcttcatcc tatatcagta ggaataacta taaggtgcac tacaaaaaga tgtatgcaaa   2460

caaacatgtt ttaaatcagg tcagatatct gatgaaaaat acgaactaat gttaagagca   2520

agtagtttca acatactcca ggaactgaga aacaaaacaa agcaattgtg ggttttgagc   2580

tccatatact cttagcaagt aagggggcgt cttgccccta tatatcatct tcccggattc   2640

cactccctgt tgtgggaatc gcgcccaccc ccatccgtgt gttgtagcca ctcacggttt   2700

gcatcaagag tgttttttgt aactgcctct ggacttggga cagtgagtag gatcaaaaat   2760

aaataatgta catgacgggg aagggaaaaa cctgttggag ttgcttccag ccagccacgc   2820

tccgggccag catgttggaa tccagcgtgg agcagatgca gtaaaaatgt ggttggtttc   2880

tgtgtg                                                              2886


<210>  5581
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  5581

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
465                 470                 475                 480


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
                485                 490                 495


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
            500                 505                 510


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
        515                 520                 525


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
    530                 535


<210>  5582
<211>  3060
<212>  DNA
<213>  Homo sapiens

<400>  5582
gcggcgggag cgccggggag gcgggcggag gcgggcggag gcggggggcg gggagcccga     60

ggggtggaag ccggcggcgg ccgagcgggg tcagttctct gtagtgtttg ccaatgttgg    120

agccgtctgc aaagtgtccc cggcaagaag aggctgccta ccacaaggac tttagcttac    180

tttttaaaga ttgaagaaaa aaaagaagac agaaaaagaa gaactcaaag atacacaaag    240

taatttgaac caaggctcag aagtttttgg agccgtgagg gatacagcag tttggtcaat    300

attgtcttaa catgcttcaa ataaatcagc ttctctccaa gataaaatgg caaacccaaa    360

agagaaaact gcaatgtgtc tggtaaatga gttagcccgt ttcaatagag tccaacccca    420

gtataaactt ctgaatgaaa gagggcctgc tcattcaaag atgttctcag tgcagctgag    480

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    540

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    600

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    660

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    720

agctaattac aactttcggg gcatgtacaa tcagaggtat cattgcccag tgcctaagat    780

cttttatgtt cagctcactg taggaaataa tgaatttttt ggggaaggaa agactcgaca    840

agctgctaga cacaatgctg caatgaaagc cctccaagca ctgcagaatg aacctattcc    900

agaaagatct cctcagaatg gtgaatcagg aaaggatgtg gatgatgaca aagatgcaaa    960

taagtctgag atcagcttag tgtttgaaat tgctctgaag cgaaatatgc ctgtcagttt   1020

tgaggttatt aaagaaagtg gaccaccaca tatgaaaagc tttgttactc gagtgtcagt   1080

aggagagttc tctgcagaag gagaaggaaa tagcaaaaaa ctctccaaga agcgcgctgc   1140

gaccaccgtc ttacaggagc ttaaaaaact tccacctctt cctgtggtgg aaaagccaaa   1200

actatttttt aaaaaacgcc ctaaaacaat agtaaaggcc ggaccagaat atggccaagg   1260

gatgaaccct attagccgcc tggcgcaaat tcaacaggcc aaaaaggaaa aggagccgga   1320

ttatgttttg ctttcagaaa gaggaatgcc tcgacgtcga gaatttgtga tgcaggtgaa   1380

ggtaggcaat gaagttgcta caggaacagg acctaataaa aagatagcca aaaaaaatgc   1440

tgcagaagca atgctgttac aacttggtta taaagcatcc actaatcttc aggatcaact   1500

tgagaagaca ggggaaaaca aaggatggag tggtccaaag cctgggtttc ctgaaccaac   1560

aaataatact ccaaaaggaa ttcttcattt gtctcctgat gtttatcaag agatggaagc   1620

cagccgccac aaagtaatct ctggcactac tctaggctat ttgtcaccca aagatatgaa   1680

ccaaccttca agctctttct tcagtatatc tcccacatcg aatagttcag ctacaattgc   1740

cagggaactc cttatgaatg gaacatcttc tacagctgaa gccataggtt taaaaggaag   1800

ttctcctact cccccttgtt ctccagtaca accttcaaaa caactggaat atttagcaag   1860

gattcaaggc tttcaggcag ccttaagtgc cttgaaacaa ttttctgaac aaggactgga   1920

tccaatcgat ggagcaatga atatcgaaaa aggttctctt gaaaaacaag ccaagcatct   1980

gagagagaaa gcggacaata accaggcacc cccgggctcc atcgctcagg actgcaagaa   2040

atcaaactcg gccgtctagc agctcccaga acccgcggct gccaccgcat ccttataaac   2100

ctgtcagcac gcatgagggt gtctgtgttc agggaaatga atgactaata ccattatttg   2160

agtcttatgt gaagacaaca ctattctaac acgagagata atatacatgg tactgtttat   2220

tcaactgggg aaaaataaaa ctttgagcat ttcccttgga actcgagatc agatcataac   2280

tcatttgcct agaggcagca gaaatctgat cctgctactg gagcttaaaa taacaagtaa   2340

agaaaagtgt tagaaacaaa gctaaaattt taacatgatt aataatagag aagttgggtt   2400

tggttctgtt gttatgattg ttttgtcgtg gtgcttgtgt tcagttatat tctctctctc   2460

tctcatttca aatactgctt gacaattcga aaatgaacca atgatgtgct gtggaatgtg   2520

atggttgtct tcatatagag tcacatggtt tctcttttta tgcagatatt tataatcttc   2580

atcctatatc agtaggaata actataaggt gcactacaaa aagatgtatg caaacaaaca   2640

tgttttaaat caggtcagat atctgatgaa aaatacgaac taatgttaag agcaagtagt   2700

ttcaacatac tccaggaact gagaaacaaa acaaagcaat tgtgggtttt gagctccata   2760

tactcttagc aagtaagggg gcgtcttgcc cctatatatc atcttcccgg attccactcc   2820

ctgttgtggg aatcgcgccc acccccatcc gtgtgttgta gccactcacg gtttgcatca   2880

agagtgtttt ttgtaactgc ctctggactt gggacagtga gtaggatcaa aaataaataa   2940

tgtacatgac ggggaaggga aaaacctgtt ggagttgctt ccagccagcc acgctccggg   3000

ccagcatgtt ggaatccagc gtggagcaga tgcagtaaaa atgtggttgg tttctgtgtg   3060


<210>  5583
<211>  570
<212>  PRT
<213>  Homo sapiens

<400>  5583

Met Ala Asn Pro Lys Glu Lys Thr Ala Met Cys Leu Val Asn Glu Leu 
1               5                   10                  15


Ala Arg Phe Asn Arg Val Gln Pro Gln Tyr Lys Leu Leu Asn Glu Arg 
            20                  25                  30


Gly Pro Ala His Ser Lys Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
        35                  40                  45


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
    50                  55                  60


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
65                  70                  75                  80


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
                85                  90                  95


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
            100                 105                 110


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
        115                 120                 125


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
    130                 135                 140


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
145                 150                 155                 160


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
                165                 170                 175


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
            180                 185                 190


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
        195                 200                 205


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
    210                 215                 220


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
225                 230                 235                 240


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
                245                 250                 255


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
            260                 265                 270


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
        275                 280                 285


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
    290                 295                 300


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
305                 310                 315                 320


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
                325                 330                 335


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
            340                 345                 350


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
        355                 360                 365


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
    370                 375                 380


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
385                 390                 395                 400


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
                405                 410                 415


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
            420                 425                 430


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
        435                 440                 445


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
    450                 455                 460


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
465                 470                 475                 480


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
                485                 490                 495


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Ala Ala 
            500                 505                 510


Leu Ser Ala Leu Lys Gln Phe Ser Glu Gln Gly Leu Asp Pro Ile Asp 
        515                 520                 525


Gly Ala Met Asn Ile Glu Lys Gly Ser Leu Glu Lys Gln Ala Lys His 
    530                 535                 540


Leu Arg Glu Lys Ala Asp Asn Asn Gln Ala Pro Pro Gly Ser Ile Ala 
545                 550                 555                 560


Gln Asp Cys Lys Lys Ser Asn Ser Ala Val 
                565                 570


<210>  5584
<211>  5156
<212>  DNA
<213>  Homo sapiens

<400>  5584
gggggcgggg agcccgaggg gtggaagccg gcggcggccg agcggggtca gttctctgta     60

gtgtttgcca atgttggagc cgtctgcaaa gtgtccccgg caagaagagg ctgcctacca    120

caaggacttt agcttacttt ttaaagattg aagaaaaaaa agaagacaga aaaagaagaa    180

ctcaaagata cacaaagtaa tttgaaccaa ggctcagaag tttttggagc cgtgagggat    240

acagcagttt ggtcaatatt gtcttaacat gcttcaaata aatcagatgt tctcagtgca    300

gctgagtctt ggtgagcaga catgggaatc cgaaggcagc agtataaaga aggctcagca    360

ggctgttgcc aataaagctt tgactgaatc tacgcttccc aaaccagttc agaagccacc    420

caaaagtaat gttaacaata acccaggcag tataactcca actgtggaac tgaatgggct    480

tgctatgaaa aggggagagc ctgccatcta caggccatta gatccaaagc cattcccaaa    540

ttatagagct aattacaact ttcggggcat gtacaatcag aggtatcatt gcccagtgcc    600

taagatcttt tatgttcagc tcactgtagg aaataatgaa ttttttgggg aaggaaagac    660

tcgacaagct gctagacaca atgctgcaat gaaagccctc caagcactgc agaatgaacc    720

tattccagaa agatctcctc agaatggtga atcaggaaag gatgtggatg atgacaaaga    780

tgcaaataag tctgagatca gcttagtgtt tgaaattgct ctgaagcgaa atatgcctgt    840

cagttttgag gttattaaag aaagtggacc accacatatg aaaagctttg ttactcgagt    900

gtcagtagga gagttctctg cagaaggaga aggaaatagc aaaaaactct ccaagaagcg    960

cgctgcgacc accgtcttac aggagcttaa aaaacttcca cctcttcctg tggtggaaaa   1020

gccaaaacta ttttttaaaa aacgccctaa aacaatagta aaggccggac cagaatatgg   1080

ccaagggatg aaccctatta gccgcctggc gcaaattcaa caggccaaaa aggaaaagga   1140

gccggattat gttttgcttt cagaaagagg aatgcctcga cgtcgagaat ttgtgatgca   1200

ggtgaaggta ggcaatgaag ttgctacagg aacaggacct aataaaaaga tagccaaaaa   1260

aaatgctgca gaagcaatgc tgttacaact tggttataaa gcatccacta atcttcagga   1320

tcaacttgag aagacagggg aaaacaaagg atggagtggt ccaaagcctg ggtttcctga   1380

accaacaaat aatactccaa aaggaattct tcatttgtct cctgatgttt atcaagagat   1440

ggaagccagc cgccacaaag taatctctgg cactactcta ggctatttgt cacccaaaga   1500

tatgaaccaa ccttcaagct ctttcttcag tatatctccc acatcgaata gttcagctac   1560

aattgccagg gaactcctta tgaatggaac atcttctaca gctgaagcca taggtttaaa   1620

aggaagttct cctactcccc cttgttctcc agtacaacct tcaaaacaac tggaatattt   1680

agcaaggatt caaggctttc aggtatgaat taaaagcaaa aacaaaaaac aaaacaattc   1740

attagcctca gattcttcat ctgtatacat cacaaggctc attcttgcct gctagtatgg   1800

cctacatgcc acttacgttt taagttattt aggaacacaa aggacagaca aaaaagccat   1860

atgcacatgc ctcattttct cttatttttg atctatctag taattctttt gctgcctgtc   1920

tcttctccat tttccttctt cttttttaag catttttcat attcttcact gtcttctatt   1980

tggtcttgat taggtgcatc tatctcttcg ctctgtcttc cacaaacaaa aattctgcct   2040

tcagacattt ggtgttagta tttcacactc agttctccct ttttttacat aaggattgag   2100

tttcttttta tgatgatttt acctttatag caattttgaa ttttgcattc tattgctagt   2160

attgattcag gtacaccatt aagatacaac attctagaag tctattacct taggagttaa   2220

ttaaacatga tatttgaaga ataatgaaat gctttatagt tgtttgaggc ataacaatgt   2280

gtatttgttt tactggatca tgttttgaac tgactaggga gggtagcacc tgcctcagat   2340

agtaccaaca attctgtttc actgggtagt ctaaaactag cttatagttt aacttaactt   2400

gttgtgtatg tgaatttagg gatggaaact ttttttcccc tatttattct ttgtttcctt   2460

ctgggaaaaa accccacaaa aatcagcact cctttatgga tacattggag cttttgaaag   2520

aattgtaaac tctaggaagg ggaaatatct gtgtcttgat ttcttagttg ccttgaaaat   2580

catgtactga actgtaaccg ctaacttgac tggatgaact agtttgcttg tgtgtagaga   2640

gtgtattgct tcctcagatt tcactgtttt catctccttt tccatcttag tctttattcc   2700

ttaagaccaa aaactgtaat atcctttaga aatgctctag aagatctgta ttgtgtagaa   2760

tgatcatgta tttataaata ttttacaagt ttagattata aaatgaaaaa gaaggtcatg   2820

tgttttgggg ggtattttgc atgttcggat ttttttttca cttcaccgaa cccttctgat   2880

tctttcaaac tattgccagg tagttgttag tgtttctaat tggactctta atatgaactt   2940

caagaagctg ttaccagtta tcggctctgt catctgaaat tttaaccact taatttaaag   3000

ttacaatttt agaatttgtt tttgttgttt taccttaaga aacacaataa atcactgttt   3060

aaaaaagatc tcaatttata taaagtactg gaaaaaagct aagtaatttt tagttctatc   3120

tataatctcc gtaggatgaa ttagaaataa attgtgatga aaagaaatta actgcttatt   3180

tatgaatcta atcatttaga aatgtctgag agtaacactg cattcttata gaaacaaagc   3240

acaaattgca ttcaagctct gaattgattt tttgcttgga gctgttgtta cagtagctgt   3300

aattttgcta ccagaatgtc ttaatttttt aaatttgttt ttatttctaa gctcttggca   3360

atgacaataa ttataatttt aacatatctt cactgtagtc aacatgtaga gtctgcttcc   3420

ctcattattg cattgctaag gcctttttaa aaagcttatg cttacataat atactctttt   3480

ttatggacac gttatatgtt tccaaatctg tgtattgtga tttttacata ctaatgaata   3540

taaacaggtg attttaaaat attactgtgc ttctttggtt gaatgagctg gtattgatgt   3600

aaaatactct gtcattgatg gaccactacc tgcagctaag cagtgagcag aatctccggg   3660

aaatgactta gtctggccac atgcatagcc catcttcata atgtcgcagc agaaggttct   3720

ttgtggttaa aagttttaaa gcctatttct ttataggtaa ccctctcagg tatatttacc   3780

tggtagaaaa acatgtagat tgtttctatt acttaaatgt tttaattgga ctgtagttta   3840

gaaattacag gaccagcttg ttacagatta tacactattc tgttactttt atttctgaaa   3900

cttaaaaaca ataaattctt tttctgtgtt tctaggttag aactttttta ttttattgca   3960

cactgaacag atactgttgc ttattgaata ttgtgtaaac ccttctttgg ctttccttgc   4020

ccattgcaat ttgatttaag cctactagag ccattgtatg tgacagctat attgtattac   4080

aaagtaaaaa tatatgagtg tattgaaaac aaagttgttt taacttttaa ttttgtttca   4140

tcacccagtc tttaatttga atttataaat tacaaaaagc tactttgatc aactgaatgt   4200

aggtatccaa gctcaaattc ttttaaacct acaaaatagg taaaattatt atacaattaa   4260

agttattaat aaaactgact taagagagca gaatgtgacc gaacacttac acattctcag   4320

cagttctgtt attcttgttt ggtctcacct aaagttttta tcgtatttta gaatcgaacc   4380

ttttggatct ctgtcagaaa tgaatgttta tttctttcaa gttttatcaa gtattaatac   4440

gttttattta tattctttta aatgttttat tcagtagttc tgtgaacttc agactttgtt   4500

gttcagccta atcgtatgct tctgtaactt ctacacattt tataagaact cattcaaagt   4560

tgtagtccta ccatagtgtt tcagggttcc ttgttgtgta cacttttact ataatggcaa   4620

aatgtttcaa aatcattcag ctttttaaag aaacttatta tgcaaaagac actcttgaaa   4680

tgctgtgcat ttgagctgaa gtgaaagaat ttgtttcatg ttgtactttg cattatttta   4740

agttttcaca tctttaatat gcttttctat gctaattata ttagaaatct ataaatataa   4800

gtggtttctt tgtttaaact agtcattaaa aattaggttg aaaatgaaag tggattattt   4860

tagcaaatcg tcccttctag atggatttca tttcagtttg ctattctgtg cctctcctgt   4920

gagcatcatc cactgtaaca gtgttgtttg tgaaaccttc cgagtatagt gtaacaaact   4980

aggttttttc cctcacataa ataatataaa gaaacactta gttggtgttt tagttaaact   5040

ataattagtt tattgtccaa aatcagggag tgttttatgg aggggcattt cattattgat   5100

cataatcatg ccatttccag caagatgaga ttgtccactt aaattaaaat cttcct       5156


<210>  5585
<211>  479
<212>  PRT
<213>  Homo sapiens

<400>  5585

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Val 
465                 470                 475


<210>  5586
<211>  4105
<212>  DNA
<213>  Homo sapiens

<400>  5586
gggggcgggg agcccgaggg gtggaagccg gcggcggccg agcggggtca gttctctgta     60

gtgtttgcca atgttggagc cgtctgcaaa gtgtccccgg caagaagagg ctgcctacca    120

caaggacttt agcttacttt ttaaagattg aagaaaaaaa agaagacaga aaaagaagaa    180

ctcaaagata cacaaagtaa tttgaaccaa ggctcagaag tttttggagc cgtgagggat    240

acagcagttt ggtcaatatt gtcttaacat gcttcaaata aatcagatgt tctcagtgca    300

gctgagtctt ggtgagcaga catgggaatc cgaaggcagc agtataaaga aggctcagca    360

ggctgttgcc aataaagctt tgactgaatc tacgcttccc aaaccagttc agaagccacc    420

caaaagtaat gttaacaata acccaggcag tataactcca actgtggaac tgaatgggct    480

tgctatgaaa aggggagagc ctgccatcta caggccatta gatccaaagc cattcccaaa    540

ttatagagct aattacaact ttcggggcat gtacaatcag aggtatcatt gcccagtgcc    600

taagatcttt tatgttcagc tcactgtagg aaataatgaa ttttttgggg aaggaaagac    660

tcgacaagct gctagacaca atgctgcaat gaaagccctc caagcactgc agaatgaacc    720

tattccagaa agatctcctc agaatggtga atcaggaaag gatgtggatg atgacaaaga    780

tgcaaataag tctgagatca gcttagtgtt tgaaattgct ctgaagcgaa atatgcctgt    840

cagttttgag gttattaaag aaagtggacc accacatatg aaaagctttg ttactcgagt    900

gtcagtagga gagttctctg cagaaggaga aggaaatagc aaaaaactct ccaagaagcg    960

cgctgcgacc accgtcttac aggagcttaa aaaacttcca cctcttcctg tggtggaaaa   1020

gccaaaacta ttttttaaaa aacgccctaa aacaatagta aaggccggac cagaatatgg   1080

ccaagggatg aaccctatta gccgcctggc gcaaattcaa caggccaaaa aggaaaagga   1140

gccggattat gttttgcttt cagaaagagg aatgcctcga cgtcgagaat ttgtgatgca   1200

ggtgaaggta ggcaatgaag ttgctacagg aacaggacct aataaaaaga tagccaaaaa   1260

aaatgctgca gaagcaatgc tgttacaact tggttataaa gcatccacta atcttcagga   1320

tcaacttgag aagacagggg aaaacaaagg atggagtggt ccaaagcctg ggtttcctga   1380

accaacaaat aatactccaa aaggaattct tcatttgtct cctgatgttt atcaagagat   1440

ggaagccagc cgccacaaag taatctctgg cactactcta ggctatttgt cacccaaaga   1500

tatgaaccaa ccttcaagct ctttcttcag tatatctccc acatcgaata gttcagctac   1560

aattgccagg gaactcctta tgaatggaac atcttctaca gctgaagcca taggtttaaa   1620

aggaagttct cctactcccc cttgttctcc agtacaacct tcaaaacaac tggaatattt   1680

agcaaggatt caaggctttc aggtatgaat taaaagcaaa aacaaaaaac aaaacaattc   1740

attagcctca gattcttcat ctgtatacat cacaaggctc attcttgcct gctagtatgg   1800

cctacatgcc acttacgttt taagttattt aggaacacaa aggacagaca aaaaagccat   1860

atgcacatgc ctcattttct cttatttttg atctatctag taattctttt gctgcctgtc   1920

tcttctccat tttccttctt cttttttaag catttttcat attcttcact gtcttctatt   1980

tggtcttgat taggtgcatc tatctcttcg ctctgtcttc cacaaacaaa aattctgcct   2040

tcagacattt ggtgttagta tttcacactc agttctccct ttttttacat aaggattgag   2100

tttcttttta tgatgatttt acctttatag caattttgaa ttttgcattc tattgctagt   2160

attgattcag gtacaccatt aagatacaac attctagaag tctattacct taggagttaa   2220

ttaaacatga tatttgaaga ataatgaaat gctttatagt tgtttgaggc ataacaatgt   2280

gtatttgttt tactggatca tgttttgaac tgactaggga gggtagcacc tgcctcagat   2340

agtaccaaca attctgtttc actgggtagt ctaaaactag cttatagttt aacttaactt   2400

gttgtgtatg tgaatttagg gatggaaact ttttttcccc tatttattct ttgtttcctt   2460

ctgggaaaaa accccacaaa aatcagcact cctttatgga tacattggag cttttgaaag   2520

aattgtaaac tctaggaagg ggaaatatct gtgtcttgat ttcttagttg ccttgaaaat   2580

catgtactga actgtaaccg ctaacttgac tggatgaact agtttgcttg tgtgtagaga   2640

gtgtattgct tcctcagatt tcactgtttt catctccttt tccatcttag tctttattcc   2700

ttaagaccaa aaactgtaat atcctttaga aatgctctag aagatctgta ttgtgtagaa   2760

tgatcatgta tttataaata ttttacaagt ttagattata aaatgaaaaa gaaggtcatg   2820

tgttttgggg ggtattttgc atgttcggat ttttttttca cttcaccgaa cccttctgat   2880

tctttcaaac tattgccagg tagttgttag tgtttctaat tggactctta atatgaactt   2940

caagaagctg ttaccagtta tcggctctgt catctgaaat tttaaccact taatttaaag   3000

ttacaatttt agaatttgtt tttgttgttt taccttaaga aacacaataa atcactgttt   3060

aaaaaagatc tcaatttata taaagtactg gaaaaaagct aagtaatttt tagttctatc   3120

tataatctcc gtaggatgaa ttagaaataa attgtgatga aaagaaatta actgcttatt   3180

tatgaatcta atcatttaga aatgtctgag agtaacactg cattcttata gaaacaaagc   3240

acaaattgca ttcaagctct gaattgattt tttgcttgga gctgttgtta cagtagctgt   3300

aattttgcta ccagaatgtc ttaatttttt aaatttgttt ttatttctaa gctcttggca   3360

atgacaataa ttataatttt aacatatctt cactgtagtc aacatgtaga gtctgcttcc   3420

ctcattattg cattgctaag gcctttttaa aaagcttatg cttacataat atactctttt   3480

ttatggacac gttatatgtt tccaaatctg tgtattgtga tttttacata ctaatgaata   3540

taaacaggtg attttaaaat attactgtgc ttctttggtt gaatgagctg gtattgatgt   3600

aaaatactct gtcattgatg gaccactacc tgcagctaag cagtgagcag aatctccggg   3660

aaatgactta gtctggccac atgcatagcc catcttcata atgtcgcagc agaaggttct   3720

ttgtggttaa aagttttaaa gcctatttct ttataggtaa ccctctcagg tatatttacc   3780

tggtagaaaa acatgtagat tgtttctatt acttaaatgt tttaattgga ctgtagttta   3840

gaaattacag gaccagcttg ttacagatta tacactattc tgttactttt atttctgaaa   3900

cttaaaaaca ataaattctt tttctgtgtt tctaggttag aactttttta ttttattgca   3960

cactgaacag atactgttgc ttattgaata ttgtgtaaac ccttctttgg ctttccttgc   4020

ccattgcaat ttgatttaag cctactagag ccattgtatg tgacagctat attgtattac   4080

aaagtaaaaa tatatgagtg tattg                                         4105


<210>  5587
<211>  479
<212>  PRT
<213>  Homo sapiens

<400>  5587

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg Tyr His Cys Pro Val Pro Lys 
            100                 105                 110


Ile Phe Tyr Val Gln Leu Thr Val Gly Asn Asn Glu Phe Phe Gly Glu 
        115                 120                 125


Gly Lys Thr Arg Gln Ala Ala Arg His Asn Ala Ala Met Lys Ala Leu 
    130                 135                 140


Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser Pro Gln Asn Gly 
145                 150                 155                 160


Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala Asn Lys Ser Glu 
                165                 170                 175


Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn Met Pro Val Ser 
            180                 185                 190


Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met Lys Ser Phe Val 
        195                 200                 205


Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly Glu Gly Asn Ser 
    210                 215                 220


Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val Leu Gln Glu Leu 
225                 230                 235                 240


Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro Lys Leu Phe Phe 
                245                 250                 255


Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro Glu Tyr Gly Gln 
            260                 265                 270


Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln Gln Ala Lys Lys 
        275                 280                 285


Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg Gly Met Pro Arg 
    290                 295                 300


Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn Glu Val Ala Thr 
305                 310                 315                 320


Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn Ala Ala Glu Ala 
                325                 330                 335


Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn Leu Gln Asp Gln 
            340                 345                 350


Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly Pro Lys Pro Gly 
        355                 360                 365


Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile Leu His Leu Ser 
    370                 375                 380


Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His Lys Val Ile Ser 
385                 390                 395                 400


Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met Asn Gln Pro Ser 
                405                 410                 415


Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser Ser Ala Thr Ile 
            420                 425                 430


Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr Ala Glu Ala Ile 
        435                 440                 445


Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser Pro Val Gln Pro 
    450                 455                 460


Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly Phe Gln Val 
465                 470                 475


<210>  5588
<211>  2679
<212>  DNA
<213>  Homo sapiens

<400>  5588
cggggagccc gaggggtgga agccggcggc ggccgagcgg ggtcagttct ctgtagtgtt     60

tgccaatgtt ggagccgtct gcaaagtgtc cccggcaaga aggtatcatt gcccagtgcc    120

taagatcttt tatgttcagc tcactgtagg aaataatgaa ttttttgggg aaggaaagac    180

tcgacaagct gctagacaca atgctgcaat gaaagccctc caagcactgc agaatgaacc    240

tattccagaa agatctcctc agaatggtga atcaggaaag gatgtggatg atgacaaaga    300

tgcaaataag tctgagatca gcttagtgtt tgaaattgct ctgaagcgaa atatgcctgt    360

cagttttgag gttattaaag aaagtggacc accacatatg aaaagctttg ttactcgagt    420

gtcagtagga gagttctctg cagaaggaga aggaaatagc aaaaaactct ccaagaagcg    480

cgctgcgacc accgtcttac aggagcttaa aaaacttcca cctcttcctg tggtggaaaa    540

gccaaaacta ttttttaaaa aacgccctaa aacaatagta aaggccggac cagaatatgg    600

ccaagggatg aaccctatta gccgcctggc gcaaattcaa caggccaaaa aggaaaagga    660

gccggattat gttttgcttt cagaaagagg aatgcctcga cgtcgagaat ttgtgatgca    720

ggtgaaggta ggcaatgaag ttgctacagg aacaggacct aataaaaaga tagccaaaaa    780

aaatgctgca gaagcaatgc tgttacaact tggttataaa gcatccacta atcttcagga    840

tcaacttgag aagacagggg aaaacaaagg atggagtggt ccaaagcctg ggtttcctga    900

accaacaaat aatactccaa aaggaattct tcatttgtct cctgatgttt atcaagagat    960

ggaagccagc cgccacaaag taatctctgg cactactcta ggctatttgt cacccaaaga   1020

tatgaaccaa ccttcaagct ctttcttcag tatatctccc acatcgaata gttcagctac   1080

aattgccagg gaactcctta tgaatggaac atcttctaca gctgaagcca taggtttaaa   1140

aggaagttct cctactcccc cttgttctcc agtacaacct tcaaaacaac tggaatattt   1200

agcaaggatt caaggctttc aggtatgaat taaaagcaaa aacaaaaaac aaaacaattc   1260

attagcctca gattcttcat ctgtatacat cacaaggctc attcttgcct gctagtatgg   1320

cctacatgcc acttacgttt taagttattt aggaacacaa aggacagaca aaaaagccat   1380

atgcacatgc ctcattttct cttatttttg atctatctag taattctttt gctgcctgtc   1440

tcttctccat tttccttctt cttttttaag catttttcat attcttcact gtcttctatt   1500

tggtcttgat taggtgcatc tatctcttcg ctctgtcttc cacaaacaaa aattctgcct   1560

tcagacattt ggtgttagta tttcacactc agttctccct ttttttacat aaggattgag   1620

tttcttttta tgatgatttt acctttatag caattttgaa ttttgcattc tattgctagt   1680

attgattcag gtacaccatt aagatacaac attctagaag tctattacct taggagttaa   1740

ttaaacatga tatttgaaga ataatgaaat gctttatagt tgtttgaggc ataacaatgt   1800

gtatttgttt tactggatca tgttttgaac tgactaggga gggtagcacc tgcctcagat   1860

agtaccaaca attctgtttc actgggtagt ctaaaactag cttatagttt aacttaactt   1920

gttgtgtatg tgaatttagg gatggaaact ttttttcccc tatttattct ttgtttcctt   1980

ctgggaaaaa accccacaaa aatcagcact cctttatgga tacattggag cttttgaaag   2040

aattgtaaac tctaggaagg ggaaatatct gtgtcttgat ttcttagttg ccttgaaaat   2100

catgtactga actgtaaccg ctaacttgac tggatgaact agtttgcttg tgtgtagaga   2160

gtgtattgct tcctcagatt tcactgtttt catctccttt tccatcttag tctttattcc   2220

ttaagaccaa aaactgtaat atcctttaga aatgctctag aagatctgta ttgtgtagaa   2280

tgatcatgta tttataaata ttttacaagt ttagattata aaatgaaaaa gaaggtcatg   2340

tgttttgggg ggtattttgc atgttcggat ttttttttca cttcaccgaa cccttctgat   2400

tctttcaaac tattgccagg tagttgttag tgtttctaat tggactctta atatgaactt   2460

caagaagctg ttaccagtta tcggctctgt catctgaaat tttaaccact taatttaaag   2520

ttacaatttt agaatttgtt tttgttgttt taccttaaga aacacaataa atcactgttt   2580

aaaaaagatc tcaatttata taaagtactg gaaaaaagct aagtaatttt tagttctatc   2640

tataatctcc gtaggatgaa ttagaaataa attgtgatg                          2679


<210>  5589
<211>  339
<212>  PRT
<213>  Homo sapiens

<400>  5589

Met Lys Ala Leu Gln Ala Leu Gln Asn Glu Pro Ile Pro Glu Arg Ser 
1               5                   10                  15


Pro Gln Asn Gly Glu Ser Gly Lys Asp Val Asp Asp Asp Lys Asp Ala 
            20                  25                  30


Asn Lys Ser Glu Ile Ser Leu Val Phe Glu Ile Ala Leu Lys Arg Asn 
        35                  40                  45


Met Pro Val Ser Phe Glu Val Ile Lys Glu Ser Gly Pro Pro His Met 
    50                  55                  60


Lys Ser Phe Val Thr Arg Val Ser Val Gly Glu Phe Ser Ala Glu Gly 
65                  70                  75                  80


Glu Gly Asn Ser Lys Lys Leu Ser Lys Lys Arg Ala Ala Thr Thr Val 
                85                  90                  95


Leu Gln Glu Leu Lys Lys Leu Pro Pro Leu Pro Val Val Glu Lys Pro 
            100                 105                 110


Lys Leu Phe Phe Lys Lys Arg Pro Lys Thr Ile Val Lys Ala Gly Pro 
        115                 120                 125


Glu Tyr Gly Gln Gly Met Asn Pro Ile Ser Arg Leu Ala Gln Ile Gln 
    130                 135                 140


Gln Ala Lys Lys Glu Lys Glu Pro Asp Tyr Val Leu Leu Ser Glu Arg 
145                 150                 155                 160


Gly Met Pro Arg Arg Arg Glu Phe Val Met Gln Val Lys Val Gly Asn 
                165                 170                 175


Glu Val Ala Thr Gly Thr Gly Pro Asn Lys Lys Ile Ala Lys Lys Asn 
            180                 185                 190


Ala Ala Glu Ala Met Leu Leu Gln Leu Gly Tyr Lys Ala Ser Thr Asn 
        195                 200                 205


Leu Gln Asp Gln Leu Glu Lys Thr Gly Glu Asn Lys Gly Trp Ser Gly 
    210                 215                 220


Pro Lys Pro Gly Phe Pro Glu Pro Thr Asn Asn Thr Pro Lys Gly Ile 
225                 230                 235                 240


Leu His Leu Ser Pro Asp Val Tyr Gln Glu Met Glu Ala Ser Arg His 
                245                 250                 255


Lys Val Ile Ser Gly Thr Thr Leu Gly Tyr Leu Ser Pro Lys Asp Met 
            260                 265                 270


Asn Gln Pro Ser Ser Ser Phe Phe Ser Ile Ser Pro Thr Ser Asn Ser 
        275                 280                 285


Ser Ala Thr Ile Ala Arg Glu Leu Leu Met Asn Gly Thr Ser Ser Thr 
    290                 295                 300


Ala Glu Ala Ile Gly Leu Lys Gly Ser Ser Pro Thr Pro Pro Cys Ser 
305                 310                 315                 320


Pro Val Gln Pro Ser Lys Gln Leu Glu Tyr Leu Ala Arg Ile Gln Gly 
                325                 330                 335


Phe Gln Val 



<210>  5590
<211>  2204
<212>  DNA
<213>  Homo sapiens

<400>  5590
ggggagcccg aggggtggaa gccggcggcg gccgagcggg gtcagttctc tgtagtgttt     60

gccaatgttg gagccgtctg caaagtgtcc ccggcaagaa gaggctgcct accacaagga    120

ctttagctta ctttttaaag attgaagaaa aaaaagaaga cagaaaaaga agaactcaaa    180

gatacacaaa gtaatttgaa ccaaggctca gaagtttttg gagccgtgag ggatacagca    240

gtttggtcaa tattgtctta acatgcttca aataaatcag atgttctcag tgcagctgag    300

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    360

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    420

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    480

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    540

agctaattac aactttcggg gcatgtacaa tcagagatga agagttacct aagtcagtgt    600

tataagatgt tccatggtaa aagggatttg aagacaaatt ttggaaatgc tgcatactgt    660

atctctcttg aagactccta aaggtgtcat gaagaaaact gtttacctaa gtggttccta    720

acactgactg aacatcaggc tttcctgggc agctttaaaa attctgatgc ccagacttta    780

tgtggactaa ttaaatcaga atttctggtt gcagagcttg aaccgcactg ttttttaaaa    840

cttccccaag taattctatg tccagtcatt taaatactgg tccccacaac ccaaaacaca    900

ttaccctcta ttaacatcaa agattatgag atggtttgaa tagtcataga acttttgaaa    960

gaagtaaaga agaagggaag aattacagtt aaccacactc cttaaggata attgttctgg   1020

acagctagct tccccacatt gctgagggtt cacttttttt tggaacctaa aactttactt   1080

agttcagtaa ttttggatag aaatatttct aaaagttatg gcatatattt tttatatcct   1140

taaatagaaa atgccacaat tcttagcatg aagaatcctt gctgttgact cattatcaac   1200

cttataaaca ataagtatta caagcctcat gagatatgta catggtttgt ccttatacca   1260

gataatccta gacatctgtt tctagagtac ccaagtgtgc ttttagttac tttccaaatc   1320

attgttgtca gtcagattgt catcttattt cttgtttttg tcagtgcacc tttgcatatt   1380

gcttgctcct ttctttgatg cttttcaatt gctattatct tgaaaaccga tattattgtt   1440

tgaatttggg gcaaagtaag agtagcaggg ctttaattac gccctaagat gtccccttaa   1500

ctgtggaaaa catcgagttt tatctagttg gtgaattttt ttacttcaga atttattttt   1560

ttctgtcata aattttgcta aggatctgca ttttgagtag aatgaagtgg ccagatagtt   1620

gaataatggt ttggtgaata tctatatgta tatatgtatg tgtatgtgtg ttacacatac   1680

atatttaatg acatgaagta ctttggttgc ttggaattgg acagaaataa cagttttttt   1740

ttttttttgg gacagagtct tgctctgtca cctaggctgg agtgcaatgg cgcgatctct   1800

gctcactgca acttccacct cccaggttca agtgattctc ctgccgcagc ctcccgagta   1860

gctgggattg caggcgcctg ccagcatgcc cgccagcacg cctggctaat tttttttttt   1920

gtatttttag tagagatggg gtttcactat gttggccagg ctggtcttgg aactcctgat   1980

ctcgtgatct gtgtgccttg gcctcccaaa gtgctgggat tacaggcgtg agccaccgcg   2040

cctggccaga aataacagtt ttaataaatt tcatgaaatc actttcttgt atgttaaagg   2100

aaacagaaag ggttcatttg tgcatggttt agtctttctt ttgaatgtgg aagtttttct   2160

tcttatttgt gtgtctaaaa aaattaaaaa gtgaaacatt ttcc                    2204


<210>  5591
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  5591

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg 
            100                 105


<210>  5592
<211>  1110
<212>  DNA
<213>  Homo sapiens

<400>  5592
gcggcgggag cgccggggag gcgggcggag gcgggcggag gcggggggcg gggagcccga     60

ggggtggaag ccggcggcgg ccgagcgggg tcagttctct gtagtgtttg ccaatgttgg    120

agccgtctgc aaagtgtccc cggcaagaag aggctgccta ccacaaggac tttagcttac    180

tttttaaaga ttgaagaaaa aaaagaagac agaaaaagaa gaactcaaag atacacaaag    240

taatttgaac caaggctcag aagtttttgg agccgtgagg gatacagcag tttggtcaat    300

attgtcttaa catgcttcaa ataaatcagc ttctctccaa gataaaatgg caaacccaaa    360

agagaaaact gcaatgtgtc tggtaaatga gttagcccgt ttcaatagag tccaacccca    420

gtataaactt ctgaatgaaa gagggcctgc tcattcaaag atgttctcag tgcagctgag    480

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    540

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    600

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    660

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    720

agctaattac aactttcggg gcatgtacaa tcagagatga agagttacct aagtcagtgt    780

tataagatgt tccatggtaa aagggatttg aagacaaatt ttggaaatgc tgcatactgt    840

atctctcttg aagactccta aaggtgtcat gaagaaaact gtttacctaa gtggttccta    900

acactgactg aacatcaggc tttcctgggc agctttaaaa attctgatgc ccagacttta    960

tgtggactaa ttaaatcaga atttctggtt gcagagcttg aaccgcactg ttttttaaaa   1020

cttccccaag taattctatg tccagtcatt taaatactgg tccccacaac ccaaaacaca   1080

ttaccctcta ttaacatcaa agattatgag                                    1110


<210>  5593
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  5593

Met Ala Asn Pro Lys Glu Lys Thr Ala Met Cys Leu Val Asn Glu Leu 
1               5                   10                  15


Ala Arg Phe Asn Arg Val Gln Pro Gln Tyr Lys Leu Leu Asn Glu Arg 
            20                  25                  30


Gly Pro Ala His Ser Lys Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
        35                  40                  45


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
    50                  55                  60


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
65                  70                  75                  80


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
                85                  90                  95


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
            100                 105                 110


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
        115                 120                 125


Asn Phe Arg Gly Met Tyr Asn Gln Arg 
    130                 135


<210>  5594
<211>  814
<212>  DNA
<213>  Homo sapiens

<400>  5594
ggggagcccg aggggtggaa gccggcggcg gccgagcggg gtcagttctc tgtagtgttt     60

gccaatgttg gagccgtctg caaagtgtcc ccggcaagaa gaggctgcct accacaagga    120

ctttagctta ctttttaaag attgaagaaa aaaaagaaga cagaaaaaga agaactcaaa    180

gatacacaaa gtaatttgaa ccaaggctca gaagtttttg gagccgtgag ggatacagca    240

gtttggtcaa tattgtctta acatgcttca aataaatcag atgttctcag tgcagctgag    300

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    360

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    420

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    480

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    540

agctaattac aactttcggg gcatgtacaa tcagagatga agagttacct aagtcagtgt    600

tataagatgt tccatggtaa aagggatttg aagacaaatt ttggaaatgc tgcatactgt    660

atctctcttg aagactccta aaggtgtcat gaagaaaact gtttacctaa gtggttccta    720

acactgactg aacatcaggc tttcctgggc agctttaaaa attctgatgc ccagacttta    780

tgtggactaa ttaaatcaga atttctggtt gcag                                814


<210>  5595
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  5595

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg 
            100                 105


<210>  5596
<211>  908
<212>  DNA
<213>  Homo sapiens

<400>  5596
gtttgccaat gttggagccg tctgcaaagt gtccccggca agaagttttt ggagccgtga     60

gggatacagc agtttggtca atattgtctt aacatgcttc aaataaatca gattgaagaa    120

ctcccttcag gatttcttgt agaacaagtc tggtgttgat gaaatccttc ggcttttgtt    180

tgtctgggaa agactttatc tctccttcat aattaaagga tattttcacc agatatacta    240

ttctagatgt tctcagtgca gctgagtctt ggtgagcaga catgggaatc cgaaggcagc    300

agtataaaga aggctcagca ggctgttgcc aataaagctt tgactgaatc tacgcttccc    360

aaaccagttc agaagccacc caaaagtaat gttaacaata acccaggcag tataactcca    420

actgtggaac tgaatgggct tgctatgaaa aggggagagc ctgccatcta caggccatta    480

gatccaaagc cattcccaaa ttatagagct aattacaact ttcggggcat gtacaatcag    540

agatggcaac acttgaatgg attacaggga ctctggagcc aaagatccaa ggagatgtct    600

tttccttgtc agaacccaga ttaatcatta gcttcttaag gcagggaatg aaaggtgaag    660

tccaagaaac agatgaagag ttacctaagt cagtgttata agatgttcca tggtaaaagg    720

gatttgaaga caaattttgg aaatgctgca tactgtatct ctcttgaaga ctcctaaagg    780

tgtcatgaag aaaactgttt acctaagtgg ttcctaacac tgactgaaca tcaggctttc    840

ctgggcagct ttaaaaattc tgatgcccag actttatgtg gactaattaa atcagaattt    900

ctggttgc                                                             908


<210>  5597
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5597

Met Phe Ser Val Gln Leu Ser Leu Gly Glu Gln Thr Trp Glu Ser Glu 
1               5                   10                  15


Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala Val Ala Asn Lys Ala Leu 
            20                  25                  30


Thr Glu Ser Thr Leu Pro Lys Pro Val Gln Lys Pro Pro Lys Ser Asn 
        35                  40                  45


Val Asn Asn Asn Pro Gly Ser Ile Thr Pro Thr Val Glu Leu Asn Gly 
    50                  55                  60


Leu Ala Met Lys Arg Gly Glu Pro Ala Ile Tyr Arg Pro Leu Asp Pro 
65                  70                  75                  80


Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr Asn Phe Arg Gly Met Tyr 
                85                  90                  95


Asn Gln Arg Trp Gln His Leu Asn Gly Leu Gln Gly Leu Trp Ser Gln 
            100                 105                 110


Arg Ser Lys Glu Met Ser Phe Pro Cys Gln Asn Pro Asp 
        115                 120                 125


<210>  5598
<211>  539
<212>  DNA
<213>  Homo sapiens

<400>  5598
aaggaagcca agaaaagctg agggtttagg cccattagca aggggaagat agtagataca     60

ctctggaagc attacctaag ggagaaaaag acggactaga tgccaccaac tgcaagtttc    120

cacacctcgt ggacaaggca cacgaccaca aagaaaagag gaactaaagg acaacacaag    180

atgcctctac agagcaaaga agcctggcat actcctcacc gcatgacaaa agtcgtcact    240

gatgggacaa gtcaatctca ggcgtctcct catagaaagc actaagaggc tgaaccattt    300

aacattccca ccagcaacat acgagggttc cagtttctcc acatcgtcct caaaaccagt    360

tactgcccgt cttttgattc tggccatcct agtaggtgag aagtggtatc ttactgtggt    420

tttcatttgc atctccctga tcactaatga tgttgagtat taatgatgtg tttatcttct    480

cagagtaact gtctattcca agtcctttgc ccatttttta gttgagcttt tttttgctg     539


<210>  5599
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  5599

Met Gly Gln Val Asn Leu Arg Arg Leu Leu Ile Glu Ser Thr Lys Arg 
1               5                   10                  15


Leu Asn His Leu Thr Phe Pro Pro Ala Thr Tyr Glu Gly Ser Ser Phe 
            20                  25                  30


Ser Thr Ser Ser Ser Lys Pro Val Thr Ala Arg Leu Leu Ile Leu Ala 
        35                  40                  45


Ile Leu Val Gly Glu Lys Trp Tyr Leu Thr Val Val Phe Ile Cys Ile 
    50                  55                  60


Ser Leu Ile Thr Asn Asp Val Glu Tyr 
65                  70


<210>  5600
<211>  793
<212>  DNA
<213>  Homo sapiens

<400>  5600
gggagcccga ggggtggaag ccggcggcgg ccgagcgggg tcagttctct gtagtgtttg     60

ccaatgttgg agccgtctgc aaagtgtccc cggcaagaag aggctgccta ccacaaggac    120

tttagcttac tttttaaaga ttgaagaaaa aaaagaagac agaaaaagaa gaactcaaag    180

atacacaaag taatttgaac caaggctcag aagtttttgg agccgtgagg gatacagcag    240

tttggtcaat attgtcttaa catgcttcaa ataaatcagc ttctctccaa gataaaatgg    300

caaacccaaa agagaaaact gcaatgtgtc tggtaaatga gttagcccgt ttcaatagag    360

tccaacccca gtataaactt ctgaatgaaa gagggcctgc tcattcaaag gcagtataac    420

tccaactgtg gaactgaatg ggcttgctat gaaaagggga gagcctgcca tctacaggcc    480

attagatcca aagccattcc caaattatag agctaattac aactttcggg gcatgtacaa    540

tcagagcctc acgtgatcac cactcagatc gagatacaga atgttcccaa tcacctctga    600

gagtttcctc agacctcttt gtctttgaca catccttctc ccagaaataa tcactatttt    660

attatcatag actagttttt gcctgttgtt gaacttttta tatctagact catacagtat    720

ttatgtgcat ctggcttctt ttactttgta taatgatttt cttgtttggg gattcatcca    780

tgttgcttat atc                                                       793


<210>  5601
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  5601

Met Lys Glu Gly Leu Leu Ile Gln Arg Gln Tyr Asn Ser Asn Cys Gly 
1               5                   10                  15


Thr Glu Trp Ala Cys Tyr Glu Lys Gly Arg Ala Cys His Leu Gln Ala 
            20                  25                  30


Ile Arg Ser Lys Ala Ile Pro Lys Leu 
        35                  40


<210>  5602
<211>  1171
<212>  DNA
<213>  Homo sapiens

<400>  5602
ggggagcccg aggggtggaa gccggcggcg gccgagcggg gtcagttctc tgtagtgttt     60

gccaatgttg gagccgtctg caaagtgtcc ccggcaagaa gaggctgcct accacaagga    120

ctttagctta ctttttaaag attgaagaaa aaaaagaaga cagaaaaaga agaactcaaa    180

gatacacaaa gtaatttgaa ccaaggctca gaagtttttg gagccgtgag ggatacagca    240

gtttggtcaa tattgtctta acatgcttca aataaatcag atgttctcag tgcagctgag    300

tcttggtgag cagacatggg aatccgaagg cagcagtata aagaaggctc agcaggctgt    360

tgccaataaa gctttgactg aatctacgct tcccaaacca gttcagaagc cacccaaaag    420

taatgttaac aataacccag gcagtataac tccaactgtg gaactgaatg ggcttgctat    480

gaaaagggga gagcctgcca tctacaggcc attagatcca aagccattcc caaattatag    540

agctaattac aactttcggg gcatgtacaa tcagaggttt gtatgtcttt tttggttttg    600

ttcttaatta ttattttatc catgttataa aagtttctca cactcaaaag agtattttca    660

ttgtaaatct aattgacctt gggcattgtg catggaattt agataaagca ggttcacaag    720

gaatatttaa attaataact taaagaaacc cagttttcag gaactagttt tttttttttt    780

tcccctaccc cacaaacgta aaagatctga aggaactagt ttttattgtg tcatgagggc    840

cctgtatttg ttgcagggaa gaccaagtct taaagtcatt tcacagttta tagtgttgac    900

tttctcattc atttaccaag cagagctcag tttttttctt gatttgtcta aatacattag    960

tgaacatgaa tgtttgtaat ttatagggaa aaaagaaaaa atgtaaataa tgtaatccca   1020

gaatttgcca ccttttatat tttcatgtac tttacattct ttttttcttt gcatttaaat   1080

atatttaacc aagttgaagt tgtcctttat atgcagtttt tgtagtactt tatgaaggta   1140

tgatagacat acagtaaaat gtacaaatct t                                  1171


<210>  5603
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  5603

Met Leu Gln Ile Asn Gln Met Phe Ser Val Gln Leu Ser Leu Gly Glu 
1               5                   10                  15


Gln Thr Trp Glu Ser Glu Gly Ser Ser Ile Lys Lys Ala Gln Gln Ala 
            20                  25                  30


Val Ala Asn Lys Ala Leu Thr Glu Ser Thr Leu Pro Lys Pro Val Gln 
        35                  40                  45


Lys Pro Pro Lys Ser Asn Val Asn Asn Asn Pro Gly Ser Ile Thr Pro 
    50                  55                  60


Thr Val Glu Leu Asn Gly Leu Ala Met Lys Arg Gly Glu Pro Ala Ile 
65                  70                  75                  80


Tyr Arg Pro Leu Asp Pro Lys Pro Phe Pro Asn Tyr Arg Ala Asn Tyr 
                85                  90                  95


Asn Phe Arg Gly Met Tyr Asn Gln Arg Phe Val Cys Leu Phe Trp Phe 
            100                 105                 110


Cys Ser 



<210>  5604
<211>  383
<212>  DNA
<213>  Homo sapiens

<400>  5604
agggttccag tttctccaca tcgtcctcaa aaccagttac tgcccgtctt ttgattctgg     60

ccatcctagt aggctatatt ctatggctac aagagacatg agcagattac agagctccac    120

acccagtctt ggaaagaaaa gtaactacta ctaagtagca gcaactttta agagaaaaga    180

atagagttcc tggtgcttgt ggcaagaagc aggaggacct tgaagccaat ctgggcttga    240

gaaagtggtt cattccccca aatacttcac tcaatgatct acctaaatgt ctgccgtctg    300

ccctcctttc ccaccaattt ccagtcaggc agcaatagcc aacagcaata ttaatagtaa    360

aattaatagc agtagtacca gca                                            383


<210>  5605
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  5605

Met Ser Ala Val Cys Pro Pro Phe Pro Pro Ile Ser Ser Gln Ala Ala 
1               5                   10                  15


Ile Ala Asn Ser Asn Ile Asn Ser Lys Ile Asn Ser Ser Ser Thr 
            20                  25                  30


<210>  5606
<211>  1919
<212>  DNA
<213>  Homo sapiens

<400>  5606
agttctctgt agtgtttgcc aatgttggag ccgtctgcaa agtgtccccg gcaagaaggt     60

aaataccctc atcgggggcg tccgggagac cccgacttcc gcgccgccgg cgaagaaggc    120

agagggcgct ggggagccct gcagttccgc agcacgggga acccggagaa aagcagcccc    180

cttcgcggcc tcccctcccc cgcgccttcc ctcccacatc gggctctcgg ggcagcagcg    240

gggaggggag accggcgggg gagggaggac agggaggcga aggaattggg gtggggggtg    300

cgtgtgtggt ggagggggtg ggacgacaca ggtgtcctga ggggaggagc cgggaggaag    360

gcgaggaggc cgggccaagt gggggtgcgg aggtcgggga gacaggaacg cggctgcggg    420

cgcgggaggc tggggttcta gggggccggg gtggtagcgg ccggaagaga ggacggcgag    480

tgcagccacg gtgtggctgc gagggagagg gagcgcctag agtagggcag gggagggcgg    540

cccggggagg gtctgcggga aatgggcctg ggggcgctgg aggcggagcg gcggggccgg    600

ggcgcgccgg agggtggcgg cggcagctat ttctgtagaa tgggctagtg gtaaagacgt    660

aacttgccga aatggggagg gtaggtgggg ccgaggggac aaaatatatc ctatgacagg    720

caagttctgc tgtggctgtt acgaactcct accgtgatgg ctcggcttaa aggggtagtt    780

ggcggtagtg accttgccgg ggtgaaggga gttgggcgag gagacaaagc tcagttacgg    840

aatccgctgt gtgagagcag gaactctagt ctcttcgggg tcgagccggg ggctgtggct    900

tgggggctgg gggtgctccg cagaggccat tgagaagcac gccactctgg gattcttagg    960

gaggcggtgg gggtaatggc cgtgggattc tggaagtctt tggaaatgtg tgtagaattt   1020

tgcatttgtg aataattttc tttggtaagg gtccatattt gctgtgatgt ccccttaccc   1080

ccatccccac tccaaagggt taagaactgc ttgagcagat agagagggac cattcaatta   1140

gggtagacct gggaatttac caaaggattt taaagtgggt ggatcctgca gaaagaaagg   1200

ctagagatga tcctttaaag atattttact gttaattgaa aacgtttttt atttaatgtt   1260

tgctttcaca attttggtga acttttgctg agcattactt ggcttctgat gcatcctgtg   1320

tttcagacca gcatcgtgaa tacttgaaat caaaattgtg atggacaggc agggtgatag   1380

taaccttgga ggagaaaaga tttcaacatt tctccaggat atttcttccc cgtccttgct   1440

ttctttagat gattcaagta cactgttgtg aactcagctg cggtggaaaa atcttattta   1500

ataaaactac caaaaccaag acttactctc catctctgtt ttgtagtatg gccagatttt   1560

cattgttcag tttgtatctt actgcaaaca agagatatca cataacactt taattgtaga   1620

ttgctgcatt ttgcagcagg cctgtattaa atttgcgaag cagttatgcc aaactatctg   1680

gtgtgtttgt gttttcctgc tatggtttca agtcaagtca ctattgccat attttattat   1740

atggtaggct agtctgaaat ttattcctaa gtgatgataa gttggtagga tatggtacat   1800

acttgctcac aaattactgc atttttcccc ataaaaacca gtgttttgta tttgtaagaa   1860

tgttgctgtg taatccaagt atgtattgtt aatttcaaat aaaatgctgt gtaattttt    1919


<210>  5607
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  5607

Met Leu Glu Pro Ser Ala Lys Cys Pro Arg Gln Glu Gly Lys Tyr Pro 
1               5                   10                  15


His Arg Gly Arg Pro Gly Asp Pro Asp Phe Arg Ala Ala Gly Glu Glu 
            20                  25                  30


Gly Arg Gly Arg Trp Gly Ala Leu Gln Phe Arg Ser Thr Gly Asn Pro 
        35                  40                  45


Glu Lys Ser Ser Pro Leu Arg Gly Leu Pro Ser Pro Ala Pro Ser Leu 
    50                  55                  60


Pro His Arg Ala Leu Gly Ala Ala Ala Gly Arg Gly Asp Arg Arg Gly 
65                  70                  75                  80


Arg Glu Asp Arg Glu Ala Lys Glu Leu Gly Trp Gly Val Arg Val Trp 
                85                  90                  95


Trp Arg Gly Trp Asp Asp Thr Gly Val Leu Arg Gly Gly Ala Gly Arg 
            100                 105                 110


Lys Ala Arg Arg Pro Gly Gln Val Gly Val Arg Arg Ser Gly Arg Gln 
        115                 120                 125


Glu Arg Gly Cys Gly Arg Gly Arg Leu Gly Phe 
    130                 135


<210>  5608
<211>  3901
<212>  DNA
<213>  Homo sapiens

<400>  5608
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagaa acgactacag aaagaactgt tggctttgca aaatgaccca cctcctggaa    120

tgaccttaaa tgagaagagt gttcaaaatt caattacaca gtcatgttta ctggtgaaaa    180

tattcctgtt catcctcatg tttatagcaa tggtcatatc tgtttatcca ttctaacaga    240

agactggtcc ccagcgctct cagtccaatc agtttgtctt agcattatta gcatgctttc    300

cagctgcaag gaaaagagac gaccaccgga taattctttt tatgtgcgaa catgtaacaa    360

gaatccaaag aaaacaaaat ggtggtatca tgatgatact tgttgatgcc actgttatca    420

tcctcctagc agaagatagt cctactgaga aaatgagcac tttgatcatt cagtctttga    480

actttaacct ttgactggaa gtgacctata ggcaatgaag actacttcct tttactgcat    540

ttttactcgt gtgcattctg ggcgcatgtt gatcgctggt tcagtccagg caactgacat    600

gcttttatta gtcatacagt attaatgcag gtgtcaggaa atgtcaaata taattccatt    660

ttttattttt atttttttaa gcttttggaa aagctccagg tcctcatgta ttgtgcaata    720

acaatgactt ccttggcggt tttggtacgt tcattgccgg caatgggcgt tgtaacagga    780

aaagttttca ttaactcctg ccattcaatg attaatgcat gatagggcct atgaaatgaa    840

cttactggtt atagtgggaa tataaataaa gtgagggatc caacattact ttaaaagtca    900

ccccaactgt ttatatttgg attctatgca ctgtgatcct aaggttaaca gcatgaatta    960

acatgcgtct ttaaaggact gtaatgaaag atcattgcat atttattgaa ttgtttatat   1020

ctactgtcaa gttgttttga catggaagat tttcaagtaa cattggcaga gaggtacagt   1080

atgttatccc tatggtgaaa ataaattaat ttgttgtata tagttcctca atctctgaag   1140

taaaggtatg agtaatatag ggtatgaatg gtttaatcaa ggctttattt tggaagtaag   1200

aaaaatggca gtgatgatta aattgctgca gtccataatt tgggcttgtt atttgtacat   1260

taaagatttt ttccaagtaa gttacactct gttaacttcc tgctagccat cagcatgagc   1320

cctactgcct aaacactatt tcatttattt atgtttggaa accccgtaaa catttttgtt   1380

tgcaatcttg tttcttttgt tataagtcaa gtttgaatgt tacaatactt ttattgaaac   1440

ttttgttaag ttttttcttg taaattttct ttacttgtga gtatcatctt gtcctttaat   1500

cctgtaccct aaaataagaa atacattttt gacagaggct taatgtttta acaaaagagt   1560

gtggacattt ttattttaaa atttaggcaa aagtcactat caaatggttg cttatttgtc   1620

tcacacagcc atatagtttt tcctggaggg ttttgttttg ttgttgttga aaagactttg   1680

cttacagcta gatgaaactt tctatagaaa aaaaaaattg ttgaaaggtc cagttctcag   1740

taccatgtga gttaatgata ctacaactaa gttcttttta aaaagtgatt aatgtatttt   1800

ataaattacc ttttcacata tgcaaaatct gtttctacta caatgttatt tttactaatg   1860

ccttattgtt gcactctttt tgaaatatcc tgcagtgaat atatgaatca atttgggctt   1920

aaaactgaaa gccagttggc tgaaaggttt gaaatacgta ccccagtaaa accattcaat   1980

caataattgg taaataatat tttaaaattg tttttaatct gtatagatga cattttgtag   2040

ctttgtacat gttgttaatt aagggcatat aattttacac tcaaagtata attgctgaac   2100

tcaggggtgg gtagacttca aaaatatgtc tgctatagaa ataacttgaa aaaaaaaatt   2160

aaaaccgtgg ccagccacca aattgtggac actgtttata tactgctagt taacaattac   2220

cacttttaaa aaattataac cgtttttgtt ctatcttgac tagataaatt ctcacaatga   2280

tctctgtcag ttttattagt tggcctgttt aaccaagaca gaaagtcttt gaattactca   2340

tagttttaaa ctgcttttaa tatgaaaatt gcagctgtaa attatgtatt ttcatatttt   2400

gcgtaactgc tctacactac tgtttgactt gatcttcttc tgggggttag ggagaaatct   2460

gtctccatat tgctggttct cttaccaaaa tgcttttata aagaaatgac cggtgacatt   2520

tattcaccaa aggaattaat atactgagtc aaagattaac aatgctatac tatagagtaa   2580

taggtcatat atagcctcaa ttgagttttt tatgacaata ttttaacata cctctctctc   2640

tacatataaa taccataaag taaactaaaa tgacacagag gaaagtagag gaaaatgaaa   2700

taatttcggt acatcttatg gtttaaagag tagaaaataa gatgaaatat cctaaaatat   2760

aggagcacag acatttaaaa ttcataatca ggctaacaac actctcttga atttaggaat   2820

cattgaaaac tccttgcact tagatttaat ttatatgtta gttacattat taaaagtcat   2880

aaggcattta tctgagtcat tgctctacag agagcaatta atggcttgta ataataaaaa   2940

gaatatttct ctgtaatgca ttgttgaaag acaaccagaa tatcaagaaa atgtatatag   3000

gaatatgcta cttgcctcct ccctgcattt cctcgtgggg cactatttgc gacataggcc   3060

tacagaatta gactttcata cttagaagat aaggtacact cttcttcttt tatttattta   3120

tttatttatt tttaggccat tcttctggtt tgccaaattc tattaagaca gtgatacatt   3180

tgcttcctta tttatgcatg cttagatcat gaacatgatg cccttctttt tttttttttt   3240

ctttggtcaa gtagggatta atgccatagg tttagagaga aggattgttt tcagttttta   3300

agagaatttt ttaaaaatac attttatggt tctcttaagg aattaatatt cacttctgaa   3360

ggacttactt gtaatatata atttatcatt ttagccagca gggaaataaa tcatttttaa   3420

tccccagaag aaagtgctgg aaatagcttc tatatagtca gcagttcacc tggagaaaga   3480

tcttaattcc ttgttgtttt gactaggaat atcaatattt ggtataaaat aactagaata   3540

gtttattacc ttttccctca tgaaatttta aatatatgca aatatatata tcattagatt   3600

cctgtggtgg ataataattt cttcagattc taaaacaggt gtctagtgac tgcttaattg   3660

tttccaagtt gcatcaaaga tgaattggta aataatggaa atgagtagtg atatgaaaat   3720

ggttatgtaa ctacatatta cttgtttctg gtaatcaagt cttatttttt aaaagcctat   3780

tgtttttcag aattgagata tttaaaactt gttataactt cttcctaaaa atagaagaga   3840

agaggaggta ctgtgtgtta caaaaatttt tttaaataaa gaattcagtg tcactagttc   3900

t                                                                   3901


<210>  5609
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  5609

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Asp Asp Thr Cys 
65                  70                  75                  80


<210>  5610
<211>  4004
<212>  DNA
<213>  Homo sapiens

<400>  5610
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagaa acgactacag aaagaactgt tggctttgca aaatgaccca cctcctggaa    120

tgaccttaaa tgagaagagt gttcaaaatt caattacaca gtggattgta gacatggaag    180

gtgcaccagg taccttatat gaaggggaaa aatttcaact tctatttaaa tttagtagtc    240

gatatccttt tgactctcct caggtcatgt ttactggtga aaatattcct gttcatcctc    300

atgtttatag caatggtcat atctgtttat ccattctaac agaagactgg tccccagcgc    360

tctcagtcca atcagtttgt cttagcatta ttagcatgct ttccagctgc aaggaaaaga    420

gacgaccacc ggataattct ttttatgtgc gaacatgtaa caagaatcca aagaaaacaa    480

aatggtggta tcatgatgat acttgttgat gccactgtta tcatcctcct agcagaagat    540

agtcctactg agaaaatgag cactttgatc attcagtctt tgaactttaa cctttgactg    600

gaagtgacct ataggcaatg aagactactt ccttttactg catttttact cgtgtgcatt    660

ctgggcgcat gttgatcgct ggttcagtcc aggcaactga catgctttta ttagtcatac    720

agtattaatg caggtgtcag gaaatgtcaa atataattcc attttttatt tttatttttt    780

taagcttttg gaaaagctcc aggtcctcat gtattgtgca ataacaatga cttccttggc    840

ggttttggta cgttcattgc cggcaatggg cgttgtaaca ggaaaagttt tcattaactc    900

ctgccattca atgattaatg catgataggg cctatgaaat gaacttactg gttatagtgg    960

gaatataaat aaagtgaggg atccaacatt actttaaaag tcaccccaac tgtttatatt   1020

tggattctat gcactgtgat cctaaggtta acagcatgaa ttaacatgcg tctttaaagg   1080

actgtaatga aagatcattg catatttatt gaattgttta tatctactgt caagttgttt   1140

tgacatggaa gattttcaag taacattggc agagaggtac agtatgttat ccctatggtg   1200

aaaataaatt aatttgttgt atatagttcc tcaatctctg aagtaaaggt atgagtaata   1260

tagggtatga atggtttaat caaggcttta ttttggaagt aagaaaaatg gcagtgatga   1320

ttaaattgct gcagtccata atttgggctt gttatttgta cattaaagat tttttccaag   1380

taagttacac tctgttaact tcctgctagc catcagcatg agccctactg cctaaacact   1440

atttcattta tttatgtttg gaaaccccgt aaacattttt gtttgcaatc ttgtttcttt   1500

tgttataagt caagtttgaa tgttacaata cttttattga aacttttgtt aagttttttc   1560

ttgtaaattt tctttacttg tgagtatcat cttgtccttt aatcctgtac cctaaaataa   1620

gaaatacatt tttgacagag gcttaatgtt ttaacaaaag agtgtggaca tttttatttt   1680

aaaatttagg caaaagtcac tatcaaatgg ttgcttattt gtctcacaca gccatatagt   1740

ttttcctgga gggttttgtt ttgttgttgt tgaaaagact ttgcttacag ctagatgaaa   1800

ctttctatag aaaaaaaaaa ttgttgaaag gtccagttct cagtaccatg tgagttaatg   1860

atactacaac taagttcttt ttaaaaagtg attaatgtat tttataaatt accttttcac   1920

atatgcaaaa tctgtttcta ctacaatgtt atttttacta atgccttatt gttgcactct   1980

ttttgaaata tcctgcagtg aatatatgaa tcaatttggg cttaaaactg aaagccagtt   2040

ggctgaaagg tttgaaatac gtaccccagt aaaaccattc aatcaataat tggtaaataa   2100

tattttaaaa ttgtttttaa tctgtataga tgacattttg tagctttgta catgttgtta   2160

attaagggca tataatttta cactcaaagt ataattgctg aactcagggg tgggtagact   2220

tcaaaaatat gtctgctata gaaataactt gaaaaaaaaa attaaaaccg tggccagcca   2280

ccaaattgtg gacactgttt atatactgct agttaacaat taccactttt aaaaaattat   2340

aaccgttttt gttctatctt gactagataa attctcacaa tgatctctgt cagttttatt   2400

agttggcctg tttaaccaag acagaaagtc tttgaattac tcatagtttt aaactgcttt   2460

taatatgaaa attgcagctg taaattatgt attttcatat tttgcgtaac tgctctacac   2520

tactgtttga cttgatcttc ttctgggggt tagggagaaa tctgtctcca tattgctggt   2580

tctcttacca aaatgctttt ataaagaaat gaccggtgac atttattcac caaaggaatt   2640

aatatactga gtcaaagatt aacaatgcta tactatagag taataggtca tatatagcct   2700

caattgagtt ttttatgaca atattttaac atacctctct ctctacatat aaataccata   2760

aagtaaacta aaatgacaca gaggaaagta gaggaaaatg aaataatttc ggtacatctt   2820

atggtttaaa gagtagaaaa taagatgaaa tatcctaaaa tataggagca cagacattta   2880

aaattcataa tcaggctaac aacactctct tgaatttagg aatcattgaa aactccttgc   2940

acttagattt aatttatatg ttagttacat tattaaaagt cataaggcat ttatctgagt   3000

cattgctcta cagagagcaa ttaatggctt gtaataataa aaagaatatt tctctgtaat   3060

gcattgttga aagacaacca gaatatcaag aaaatgtata taggaatatg ctacttgcct   3120

cctccctgca tttcctcgtg gggcactatt tgcgacatag gcctacagaa ttagactttc   3180

atacttagaa gataaggtac actcttcttc ttttatttat ttatttattt atttttaggc   3240

cattcttctg gtttgccaaa ttctattaag acagtgatac atttgcttcc ttatttatgc   3300

atgcttagat catgaacatg atgcccttct tttttttttt tttctttggt caagtaggga   3360

ttaatgccat aggtttagag agaaggattg ttttcagttt ttaagagaat tttttaaaaa   3420

tacattttat ggttctctta aggaattaat attcacttct gaaggactta cttgtaatat   3480

ataatttatc attttagcca gcagggaaat aaatcatttt taatccccag aagaaagtgc   3540

tggaaatagc ttctatatag tcagcagttc acctggagaa agatcttaat tccttgttgt   3600

tttgactagg aatatcaata tttggtataa aataactaga atagtttatt accttttccc   3660

tcatgaaatt ttaaatatat gcaaatatat atatcattag attcctgtgg tggataataa   3720

tttcttcaga ttctaaaaca ggtgtctagt gactgcttaa ttgtttccaa gttgcatcaa   3780

agatgaattg gtaaataatg gaaatgagta gtgatatgaa aatggttatg taactacata   3840

ttacttgttt ctggtaatca agtcttattt tttaaaagcc tattgttttt cagaattgag   3900

atatttaaaa cttgttataa cttcttccta aaaatagaag agaagaggag gtactgtgtg   3960

ttacaaaaat ttttttaaat aaagaattca gtgtcactag ttct                    4004


<210>  5611
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5611

Met Ala Ser Met Gln Lys Arg Leu Gln Lys Glu Leu Leu Ala Leu Gln 
1               5                   10                  15


Asn Asp Pro Pro Pro Gly Met Thr Leu Asn Glu Lys Ser Val Gln Asn 
            20                  25                  30


Ser Ile Thr Gln Trp Ile Val Asp Met Glu Gly Ala Pro Gly Thr Leu 
        35                  40                  45


Tyr Glu Gly Glu Lys Phe Gln Leu Leu Phe Lys Phe Ser Ser Arg Tyr 
    50                  55                  60


Pro Phe Asp Ser Pro Gln Val Met Phe Thr Gly Glu Asn Ile Pro Val 
65                  70                  75                  80


His Pro His Val Tyr Ser Asn Gly His Ile Cys Leu Ser Ile Leu Thr 
                85                  90                  95


Glu Asp Trp Ser Pro Ala Leu Ser Val Gln Ser Val Cys Leu Ser Ile 
            100                 105                 110


Ile Ser Met Leu Ser Ser Cys Lys Glu Lys Arg Arg Pro Pro Asp Asn 
        115                 120                 125


Ser Phe Tyr Val Arg Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp 
    130                 135                 140


Trp Tyr His Asp Asp Thr Cys 
145                 150


<210>  5612
<211>  4037
<212>  DNA
<213>  Homo sapiens

<400>  5612
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagac cacaggaagg agggtggaag tatggtttcc aaaacgacta cagaaagaac    120

tgttggcttt gcaaaatgac ccacctcctg gaatgacctt aaatgagaag agtgttcaaa    180

attcaattac acagtggatt gtagacatgg aaggtgcacc aggtacctta tatgaagggg    240

aaaaatttca acttctattt aaatttagta gtcgatatcc ttttgactct cctcaggtca    300

tgtttactgg tgaaaatatt cctgttcatc ctcatgttta tagcaatggt catatctgtt    360

tatccattct aacagaagac tggtccccag cgctctcagt ccaatcagtt tgtcttagca    420

ttattagcat gctttccagc tgcaaggaaa agagacgacc accggataat tctttttatg    480

tgcgaacatg taacaagaat ccaaagaaaa caaaatggtg gtatcatgat gatacttgtt    540

gatgccactg ttatcatcct cctagcagaa gatagtccta ctgagaaaat gagcactttg    600

atcattcagt ctttgaactt taacctttga ctggaagtga cctataggca atgaagacta    660

cttcctttta ctgcattttt actcgtgtgc attctgggcg catgttgatc gctggttcag    720

tccaggcaac tgacatgctt ttattagtca tacagtatta atgcaggtgt caggaaatgt    780

caaatataat tccatttttt atttttattt ttttaagctt ttggaaaagc tccaggtcct    840

catgtattgt gcaataacaa tgacttcctt ggcggttttg gtacgttcat tgccggcaat    900

gggcgttgta acaggaaaag ttttcattaa ctcctgccat tcaatgatta atgcatgata    960

gggcctatga aatgaactta ctggttatag tgggaatata aataaagtga gggatccaac   1020

attactttaa aagtcacccc aactgtttat atttggattc tatgcactgt gatcctaagg   1080

ttaacagcat gaattaacat gcgtctttaa aggactgtaa tgaaagatca ttgcatattt   1140

attgaattgt ttatatctac tgtcaagttg ttttgacatg gaagattttc aagtaacatt   1200

ggcagagagg tacagtatgt tatccctatg gtgaaaataa attaatttgt tgtatatagt   1260

tcctcaatct ctgaagtaaa ggtatgagta atatagggta tgaatggttt aatcaaggct   1320

ttattttgga agtaagaaaa atggcagtga tgattaaatt gctgcagtcc ataatttggg   1380

cttgttattt gtacattaaa gattttttcc aagtaagtta cactctgtta acttcctgct   1440

agccatcagc atgagcccta ctgcctaaac actatttcat ttatttatgt ttggaaaccc   1500

cgtaaacatt tttgtttgca atcttgtttc ttttgttata agtcaagttt gaatgttaca   1560

atacttttat tgaaactttt gttaagtttt ttcttgtaaa ttttctttac ttgtgagtat   1620

catcttgtcc tttaatcctg taccctaaaa taagaaatac atttttgaca gaggcttaat   1680

gttttaacaa aagagtgtgg acatttttat tttaaaattt aggcaaaagt cactatcaaa   1740

tggttgctta tttgtctcac acagccatat agtttttcct ggagggtttt gttttgttgt   1800

tgttgaaaag actttgctta cagctagatg aaactttcta tagaaaaaaa aaattgttga   1860

aaggtccagt tctcagtacc atgtgagtta atgatactac aactaagttc tttttaaaaa   1920

gtgattaatg tattttataa attacctttt cacatatgca aaatctgttt ctactacaat   1980

gttattttta ctaatgcctt attgttgcac tctttttgaa atatcctgca gtgaatatat   2040

gaatcaattt gggcttaaaa ctgaaagcca gttggctgaa aggtttgaaa tacgtacccc   2100

agtaaaacca ttcaatcaat aattggtaaa taatatttta aaattgtttt taatctgtat   2160

agatgacatt ttgtagcttt gtacatgttg ttaattaagg gcatataatt ttacactcaa   2220

agtataattg ctgaactcag gggtgggtag acttcaaaaa tatgtctgct atagaaataa   2280

cttgaaaaaa aaaattaaaa ccgtggccag ccaccaaatt gtggacactg tttatatact   2340

gctagttaac aattaccact tttaaaaaat tataaccgtt tttgttctat cttgactaga   2400

taaattctca caatgatctc tgtcagtttt attagttggc ctgtttaacc aagacagaaa   2460

gtctttgaat tactcatagt tttaaactgc ttttaatatg aaaattgcag ctgtaaatta   2520

tgtattttca tattttgcgt aactgctcta cactactgtt tgacttgatc ttcttctggg   2580

ggttagggag aaatctgtct ccatattgct ggttctctta ccaaaatgct tttataaaga   2640

aatgaccggt gacatttatt caccaaagga attaatatac tgagtcaaag attaacaatg   2700

ctatactata gagtaatagg tcatatatag cctcaattga gttttttatg acaatatttt   2760

aacatacctc tctctctaca tataaatacc ataaagtaaa ctaaaatgac acagaggaaa   2820

gtagaggaaa atgaaataat ttcggtacat cttatggttt aaagagtaga aaataagatg   2880

aaatatccta aaatatagga gcacagacat ttaaaattca taatcaggct aacaacactc   2940

tcttgaattt aggaatcatt gaaaactcct tgcacttaga tttaatttat atgttagtta   3000

cattattaaa agtcataagg catttatctg agtcattgct ctacagagag caattaatgg   3060

cttgtaataa taaaaagaat atttctctgt aatgcattgt tgaaagacaa ccagaatatc   3120

aagaaaatgt atataggaat atgctacttg cctcctccct gcatttcctc gtggggcact   3180

atttgcgaca taggcctaca gaattagact ttcatactta gaagataagg tacactcttc   3240

ttcttttatt tatttattta tttattttta ggccattctt ctggtttgcc aaattctatt   3300

aagacagtga tacatttgct tccttattta tgcatgctta gatcatgaac atgatgccct   3360

tctttttttt ttttttcttt ggtcaagtag ggattaatgc cataggttta gagagaagga   3420

ttgttttcag tttttaagag aattttttaa aaatacattt tatggttctc ttaaggaatt   3480

aatattcact tctgaaggac ttacttgtaa tatataattt atcattttag ccagcaggga   3540

aataaatcat ttttaatccc cagaagaaag tgctggaaat agcttctata tagtcagcag   3600

ttcacctgga gaaagatctt aattccttgt tgttttgact aggaatatca atatttggta   3660

taaaataact agaatagttt attacctttt ccctcatgaa attttaaata tatgcaaata   3720

tatatatcat tagattcctg tggtggataa taatttcttc agattctaaa acaggtgtct   3780

agtgactgct taattgtttc caagttgcat caaagatgaa ttggtaaata atggaaatga   3840

gtagtgatat gaaaatggtt atgtaactac atattacttg tttctggtaa tcaagtctta   3900

ttttttaaaa gcctattgtt tttcagaatt gagatattta aaacttgtta taacttcttc   3960

ctaaaaatag aagagaagag gaggtactgt gtgttacaaa aattttttta aataaagaat   4020

tcagtgtcac tagttct                                                  4037


<210>  5613
<211>  162
<212>  PRT
<213>  Homo sapiens

<400>  5613

Met Ala Ser Met Gln Thr Thr Gly Arg Arg Val Glu Val Trp Phe Pro 
1               5                   10                  15


Lys Arg Leu Gln Lys Glu Leu Leu Ala Leu Gln Asn Asp Pro Pro Pro 
            20                  25                  30


Gly Met Thr Leu Asn Glu Lys Ser Val Gln Asn Ser Ile Thr Gln Trp 
        35                  40                  45


Ile Val Asp Met Glu Gly Ala Pro Gly Thr Leu Tyr Glu Gly Glu Lys 
    50                  55                  60


Phe Gln Leu Leu Phe Lys Phe Ser Ser Arg Tyr Pro Phe Asp Ser Pro 
65                  70                  75                  80


Gln Val Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr 
                85                  90                  95


Ser Asn Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro 
            100                 105                 110


Ala Leu Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser 
        115                 120                 125


Ser Cys Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg 
    130                 135                 140


Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Asp Asp 
145                 150                 155                 160


Thr Cys 



<210>  5614
<211>  3534
<212>  DNA
<213>  Homo sapiens

<400>  5614
agaaacgact acagaaagaa ctgttggctt tgcaaaatga cccacctcct ggaatgacct     60

taaatgagaa gagtgttcaa aattcaatta cacagtcatg tttactggtg aaaatattcc    120

tgttcatcct catgtttata gcaatggtca tatctgttta tccattctaa cagaagactg    180

gtccccagcg ctctcagtcc aatcagtttg tcttagcatt attagcatgc tttccagctg    240

caaggaaaag ggcaaagcag tttgtgggta caaggccttc tatgttcctg ttacgcttaa    300

agactataga aagagacgac caccggataa ttctttttat gtgcgaacat gtaacaagaa    360

tccaaagaaa acaaaatggt ggtatcatga tgatacttgt tgatgccact gttatcatcc    420

tcctagcaga agatagtcct actgagaaaa tgagcacttt gatcattcag tctttgaact    480

tactggttat agtgggaata taaataaagt gagggatcca acattacttt aaaagtcacc    540

ccaactgttt atatttggat tctatgcact gtgatcctaa ggttaacagc atgaattaac    600

atgcgtcttt aaaggactgt aatgaaagat cattgcatat ttattgaatt gtttatatct    660

actgtcaagt tgttttgaca tggaagattt tcaagtaaca ttggcagaga ggtacagtat    720

gttatcccta tggtgaaaat aaattaattt gttgtatata gttcctcaat ctctgaagta    780

aaggtatgag taatataggg tatgaatggt ttaatcaagg ctttattttg gaagtaagaa    840

aaatggcagt gatgattaaa ttgctgcagt ccataatttg ggcttgttat ttgtacatta    900

aagatttttt ccaagtaagt tacactctgt taacttcctg ctagccatca gcatgagccc    960

tactgcctaa acactatttc atttatttat gtttggaaac cccgtaaaca tttttgtttg   1020

caatcttgtt tcttttgtta taagtcaagt ttgaatgtta caatactttt attgaaactt   1080

ttgttaagtt ttttcttgta aattttcttt acttgtgagt atcatcttgt cctttaatcc   1140

tgtaccctaa aataagaaat acatttttga cagaggctta atgttttaac aaaagagtgt   1200

ggacattttt attttaaaat ttaggcaaaa gtcactatca aatggttgct tatttgtctc   1260

acacagccat atagtttttc ctggagggtt ttgttttgtt gttgttgaaa agactttgct   1320

tacagctaga tgaaactttc tatagaaaaa aaaaattgtt gaaaggtcca gttctcagta   1380

ccatgtgagt taatgatact acaactaagt tctttttaaa aagtgattaa tgtattttat   1440

aaattacctt ttcacatatg caaaatctgt ttctactaca atgttatttt tactaatgcc   1500

ttattgttgc actctttttg aaatatcctg cagtgaatat atgaatcaat ttgggcttaa   1560

aactgaaagc cagttggctg aaaggtttga aatacgtacc ccagtaaaac cattcaatca   1620

ataattggta aataatattt taaaattgtt tttaatctgt atagatgaca ttttgtagct   1680

ttgtacatgt tgttaattaa gggcatataa ttttacactc aaagtataat tgctgaactc   1740

aggggtgggt agacttcaaa aatatgtctg ctatagaaat aacttgaaaa aaaaaattaa   1800

aaccgtggcc agccaccaaa ttgtggacac tgtttatata ctgctagtta acaattacca   1860

cttttaaaaa attataaccg tttttgttct atcttgacta gataaattct cacaatgatc   1920

tctgtcagtt ttattagttg gcctgtttaa ccaagacaga aagtctttga attactcata   1980

gttttaaact gcttttaata tgaaaattgc agctgtaaat tatgtatttt catattttgc   2040

gtaactgctc tacactactg tttgacttga tcttcttctg ggggttaggg agaaatctgt   2100

ctccatattg ctggttctct taccaaaatg cttttataaa gaaatgaccg gtgacattta   2160

ttcaccaaag gaattaatat actgagtcaa agattaacaa tgctatacta tagagtaata   2220

ggtcatatat agcctcaatt gagtttttta tgacaatatt ttaacatacc tctctctcta   2280

catataaata ccataaagta aactaaaatg acacagagga aagtagagga aaatgaaata   2340

atttcggtac atcttatggt ttaaagagta gaaaataaga tgaaatatcc taaaatatag   2400

gagcacagac atttaaaatt cataatcagg ctaacaacac tctcttgaat ttaggaatca   2460

ttgaaaactc cttgcactta gatttaattt atatgttagt tacattatta aaagtcataa   2520

ggcatttatc tgagtcattg ctctacagag agcaattaat ggcttgtaat aataaaaaga   2580

atatttctct gtaatgcatt gttgaaagac aaccagaata tcaagaaaat gtatatagga   2640

atatgctact tgcctcctcc ctgcatttcc tcgtggggca ctatttgcga cataggccta   2700

cagaattaga ctttcatact tagaagataa ggtacactct tcttctttta tttatttatt   2760

tatttatttt taggccattc ttctggtttg ccaaattcta ttaagacagt gatacatttg   2820

cttccttatt tatgcatgct tagatcatga acatgatgcc cttctttttt ttttttttct   2880

ttggtcaagt agggattaat gccataggtt tagagagaag gattgttttc agtttttaag   2940

agaatttttt aaaaatacat tttatggttc tcttaaggaa ttaatattca cttctgaagg   3000

acttacttgt aatatataat ttatcatttt agccagcagg gaaataaatc atttttaatc   3060

cccagaagaa agtgctggaa atagcttcta tatagtcagc agttcacctg gagaaagatc   3120

ttaattcctt gttgttttga ctaggaatat caatatttgg tataaaataa ctagaatagt   3180

ttattacctt ttccctcatg aaattttaaa tatatgcaaa tatatatatc attagattcc   3240

tgtggtggat aataatttct tcagattcta aaacaggtgt ctagtgactg cttaattgtt   3300

tccaagttgc atcaaagatg aattggtaaa taatggaaat gagtagtgat atgaaaatgg   3360

ttatgtaact acatattact tgtttctggt aatcaagtct tattttttaa aagcctattg   3420

tttttcagaa ttgagatatt taaaacttgt tataacttct tcctaaaaat agaagagaag   3480

aggaggtact gtgtgttaca aaaatttttt taaataaaga attcagtgtc acta         3534


<210>  5615
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  5615

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Gly Lys Ala Val Cys Gly Tyr Lys Ala Phe Tyr Val Pro 
    50                  55                  60


Val Thr Leu Lys Asp Tyr Arg Lys Arg Arg Pro Pro Asp Asn Ser Phe 
65                  70                  75                  80


Tyr Val Arg Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr 
                85                  90                  95


His Asp Asp Thr Cys 
            100


<210>  5616
<211>  3959
<212>  DNA
<213>  Homo sapiens

<400>  5616
ggcctcgccg gtcttggggg gatggttcca tcatggcgtc aatgcagaaa cgactacaga     60

aagaactgtt ggctttgcaa aatgacccac ctcctggaat gaccttaaat gagaagagtg    120

ttcaaaattc aattacacag tcatgtttac tggtgaaaat attcctgttc atcctcatgt    180

ttatagcaat ggtcatatct gtttatccat tctaacagaa gactggtccc cagcgctctc    240

agtccaatca gtttgtctta gcattattag catgctttcc agctgcaagg aaaagagacg    300

accaccggat aattcttttt atgtgcgaac atgtaacaag aatccaaaga aaacaaaatg    360

gtggtatcat gccatcatgg attcgtagtc ccgcaagtcc ctgttgatct agctgttaca    420

gatcatttgt ttcttcaaaa cgagggtatt caaagatgat acttgttgat gccactgtta    480

tcatcctcct agcagaagat agtcctactg agaaaatgag cactttgatc attcagtctt    540

tgaactttaa cctttgactg gaagtgacct ataggcaatg aagactactt ccttttactg    600

catttttact cgtgtgcatt ctgggcgcat gttgatcgct ggttcagtcc aggcaactga    660

catgctttta ttagtcatac agtattaatg caggtgtcag gaaatgtcaa atataattcc    720

attttttatt tttatttttt taagcttttg gaaaagctcc aggtcctcat gtattgtgca    780

ataacaatga cttccttggc ggttttggta cgttcattgc cggcaatggg cgttgtaaca    840

ggaaaagttt tcattaactc ctgccattca atgattaatg catgataggg cctatgaaat    900

gaacttactg gttatagtgg gaatataaat aaagtgaggg atccaacatt actttaaaag    960

tcaccccaac tgtttatatt tggattctat gcactgtgat cctaaggtta acagcatgaa   1020

ttaacatgcg tctttaaagg actgtaatga aagatcattg catatttatt gaattgttta   1080

tatctactgt caagttgttt tgacatggaa gattttcaag taacattggc agagaggtac   1140

agtatgttat ccctatggtg aaaataaatt aatttgttgt atatagttcc tcaatctctg   1200

aagtaaaggt atgagtaata tagggtatga atggtttaat caaggcttta ttttggaagt   1260

aagaaaaatg gcagtgatga ttaaattgct gcagtccata atttgggctt gttatttgta   1320

cattaaagat tttttccaag taagttacac tctgttaact tcctgctagc catcagcatg   1380

agccctactg cctaaacact atttcattta tttatgtttg gaaaccccgt aaacattttt   1440

gtttgcaatc ttgtttcttt tgttataagt caagtttgaa tgttacaata cttttattga   1500

aacttttgtt aagttttttc ttgtaaattt tctttacttg tgagtatcat cttgtccttt   1560

aatcctgtac cctaaaataa gaaatacatt tttgacagag gcttaatgtt ttaacaaaag   1620

agtgtggaca tttttatttt aaaatttagg caaaagtcac tatcaaatgg ttgcttattt   1680

gtctcacaca gccatatagt ttttcctgga gggttttgtt ttgttgttgt tgaaaagact   1740

ttgcttacag ctagatgaaa ctttctatag aaaaaaaaaa ttgttgaaag gtccagttct   1800

cagtaccatg tgagttaatg atactacaac taagttcttt ttaaaaagtg attaatgtat   1860

tttataaatt accttttcac atatgcaaaa tctgtttcta ctacaatgtt atttttacta   1920

atgccttatt gttgcactct ttttgaaata tcctgcagtg aatatatgaa tcaatttggg   1980

cttaaaactg aaagccagtt ggctgaaagg tttgaaatac gtaccccagt aaaaccattc   2040

aatcaataat tggtaaataa tattttaaaa ttgtttttaa tctgtataga tgacattttg   2100

tagctttgta catgttgtta attaagggca tataatttta cactcaaagt ataattgctg   2160

aactcagggg tgggtagact tcaaaaatat gtctgctata gaaataactt gaaaaaaaaa   2220

attaaaaccg tggccagcca ccaaattgtg gacactgttt atatactgct agttaacaat   2280

taccactttt aaaaaattat aaccgttttt gttctatctt gactagataa attctcacaa   2340

tgatctctgt cagttttatt agttggcctg tttaaccaag acagaaagtc tttgaattac   2400

tcatagtttt aaactgcttt taatatgaaa attgcagctg taaattatgt attttcatat   2460

tttgcgtaac tgctctacac tactgtttga cttgatcttc ttctgggggt tagggagaaa   2520

tctgtctcca tattgctggt tctcttacca aaatgctttt ataaagaaat gaccggtgac   2580

atttattcac caaaggaatt aatatactga gtcaaagatt aacaatgcta tactatagag   2640

taataggtca tatatagcct caattgagtt ttttatgaca atattttaac atacctctct   2700

ctctacatat aaataccata aagtaaacta aaatgacaca gaggaaagta gaggaaaatg   2760

aaataatttc ggtacatctt atggtttaaa gagtagaaaa taagatgaaa tatcctaaaa   2820

tataggagca cagacattta aaattcataa tcaggctaac aacactctct tgaatttagg   2880

aatcattgaa aactccttgc acttagattt aatttatatg ttagttacat tattaaaagt   2940

cataaggcat ttatctgagt cattgctcta cagagagcaa ttaatggctt gtaataataa   3000

aaagaatatt tctctgtaat gcattgttga aagacaacca gaatatcaag aaaatgtata   3060

taggaatatg ctacttgcct cctccctgca tttcctcgtg gggcactatt tgcgacatag   3120

gcctacagaa ttagactttc atacttagaa gataaggtac actcttcttc ttttatttat   3180

ttatttattt atttttaggc cattcttctg gtttgccaaa ttctattaag acagtgatac   3240

atttgcttcc ttatttatgc atgcttagat catgaacatg atgcccttct tttttttttt   3300

tttctttggt caagtaggga ttaatgccat aggtttagag agaaggattg ttttcagttt   3360

ttaagagaat tttttaaaaa tacattttat ggttctctta aggaattaat attcacttct   3420

gaaggactta cttgtaatat ataatttatc attttagcca gcagggaaat aaatcatttt   3480

taatccccag aagaaagtgc tggaaatagc ttctatatag tcagcagttc acctggagaa   3540

agatcttaat tccttgttgt tttgactagg aatatcaata tttggtataa aataactaga   3600

atagtttatt accttttccc tcatgaaatt ttaaatatat gcaaatatat atatcattag   3660

attcctgtgg tggataataa tttcttcaga ttctaaaaca ggtgtctagt gactgcttaa   3720

ttgtttccaa gttgcatcaa agatgaattg gtaaataatg gaaatgagta gtgatatgaa   3780

aatggttatg taactacata ttacttgttt ctggtaatca agtcttattt tttaaaagcc   3840

tattgttttt cagaattgag atatttaaaa cttgttataa cttcttccta aaaatagaag   3900

agaagaggag gtactgtgtg ttacaaaaat ttttttaaat aaagaattca gtgtcacta    3959


<210>  5617
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  5617

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Ala Ile Met Asp 
65                  70                  75                  80


Ser 



<210>  5618
<211>  4005
<212>  DNA
<213>  Homo sapiens

<400>  5618
gtctctggcc tcgccggtct tggggggatg gttccatcat ggcgtcaatg cagaaacgac     60

tacagaaaga actgttggct ttgcaaaatg acccacctcc tggaatgacc ttaaatgaga    120

agagtgttca aaattcaatt acacagtcat gtttactggt gaaaatattc ctgttcatcc    180

tcatgtttat agcaatggtc atatctgttt atccattcta acagaagact ggtccccagc    240

gctctcagtc caatcagttt gtcttagcat tattagcatg ctttccagct gcaaggaaaa    300

gagacgacca ccggataatt ctttttatgt gcgaacatgt aacaagaatc caaagaaaac    360

aaaatggtgg tatcatgagg caacattttg ccgtattgcc taggctggtc ttgaactcct    420

gggcccaagc agtccatcca cctcagcctc cccaaatgct ggaattacag gcgtgagcca    480

ctttgcattg ccaagaaaat tatgatactt gttgatgcca ctgttatcat cctcctagca    540

gaagatagtc ctactgagaa aatgagcact ttgatcattc agtctttgaa ctttaacctt    600

tgactggaag tgacctatag gcaatgaaga ctacttcctt ttactgcatt tttactcgtg    660

tgcattctgg gcgcatgttg atcgctggtt cagtccaggc aactgacatg cttttattag    720

tcatacagta ttaatgcagg tgtcaggaaa tgtcaaatat aattccattt tttattttta    780

tttttttaag cttttggaaa agctccaggt cctcatgtat tgtgcaataa caatgacttc    840

cttggcggtt ttggtacgtt cattgccggc aatgggcgtt gtaacaggaa aagttttcat    900

taactcctgc cattcaatga ttaatgcatg atagggccta tgaaatgaac ttactggtta    960

tagtgggaat ataaataaag tgagggatcc aacattactt taaaagtcac cccaactgtt   1020

tatatttgga ttctatgcac tgtgatccta aggttaacag catgaattaa catgcgtctt   1080

taaaggactg taatgaaaga tcattgcata tttattgaat tgtttatatc tactgtcaag   1140

ttgttttgac atggaagatt ttcaagtaac attggcagag aggtacagta tgttatccct   1200

atggtgaaaa taaattaatt tgttgtatat agttcctcaa tctctgaagt aaaggtatga   1260

gtaatatagg gtatgaatgg tttaatcaag gctttatttt ggaagtaaga aaaatggcag   1320

tgatgattaa attgctgcag tccataattt gggcttgtta tttgtacatt aaagattttt   1380

tccaagtaag ttacactctg ttaacttcct gctagccatc agcatgagcc ctactgccta   1440

aacactattt catttattta tgtttggaaa ccccgtaaac atttttgttt gcaatcttgt   1500

ttcttttgtt ataagtcaag tttgaatgtt acaatacttt tattgaaact tttgttaagt   1560

tttttcttgt aaattttctt tacttgtgag tatcatcttg tcctttaatc ctgtacccta   1620

aaataagaaa tacatttttg acagaggctt aatgttttaa caaaagagtg tggacatttt   1680

tattttaaaa tttaggcaaa agtcactatc aaatggttgc ttatttgtct cacacagcca   1740

tatagttttt cctggagggt tttgttttgt tgttgttgaa aagactttgc ttacagctag   1800

atgaaacttt ctatagaaaa aaaaaattgt tgaaaggtcc agttctcagt accatgtgag   1860

ttaatgatac tacaactaag ttctttttaa aaagtgatta atgtatttta taaattacct   1920

tttcacatat gcaaaatctg tttctactac aatgttattt ttactaatgc cttattgttg   1980

cactcttttt gaaatatcct gcagtgaata tatgaatcaa tttgggctta aaactgaaag   2040

ccagttggct gaaaggtttg aaatacgtac cccagtaaaa ccattcaatc aataattggt   2100

aaataatatt ttaaaattgt ttttaatctg tatagatgac attttgtagc tttgtacatg   2160

ttgttaatta agggcatata attttacact caaagtataa ttgctgaact caggggtggg   2220

tagacttcaa aaatatgtct gctatagaaa taacttgaaa aaaaaaatta aaaccgtggc   2280

cagccaccaa attgtggaca ctgtttatat actgctagtt aacaattacc acttttaaaa   2340

aattataacc gtttttgttc tatcttgact agataaattc tcacaatgat ctctgtcagt   2400

tttattagtt ggcctgttta accaagacag aaagtctttg aattactcat agttttaaac   2460

tgcttttaat atgaaaattg cagctgtaaa ttatgtattt tcatattttg cgtaactgct   2520

ctacactact gtttgacttg atcttcttct gggggttagg gagaaatctg tctccatatt   2580

gctggttctc ttaccaaaat gcttttataa agaaatgacc ggtgacattt attcaccaaa   2640

ggaattaata tactgagtca aagattaaca atgctatact atagagtaat aggtcatata   2700

tagcctcaat tgagtttttt atgacaatat tttaacatac ctctctctct acatataaat   2760

accataaagt aaactaaaat gacacagagg aaagtagagg aaaatgaaat aatttcggta   2820

catcttatgg tttaaagagt agaaaataag atgaaatatc ctaaaatata ggagcacaga   2880

catttaaaat tcataatcag gctaacaaca ctctcttgaa tttaggaatc attgaaaact   2940

ccttgcactt agatttaatt tatatgttag ttacattatt aaaagtcata aggcatttat   3000

ctgagtcatt gctctacaga gagcaattaa tggcttgtaa taataaaaag aatatttctc   3060

tgtaatgcat tgttgaaaga caaccagaat atcaagaaaa tgtatatagg aatatgctac   3120

ttgcctcctc cctgcatttc ctcgtggggc actatttgcg acataggcct acagaattag   3180

actttcatac ttagaagata aggtacactc ttcttctttt atttatttat ttatttattt   3240

ttaggccatt cttctggttt gccaaattct attaagacag tgatacattt gcttccttat   3300

ttatgcatgc ttagatcatg aacatgatgc ccttcttttt tttttttttc tttggtcaag   3360

tagggattaa tgccataggt ttagagagaa ggattgtttt cagtttttaa gagaattttt   3420

taaaaataca ttttatggtt ctcttaagga attaatattc acttctgaag gacttacttg   3480

taatatataa tttatcattt tagccagcag ggaaataaat catttttaat ccccagaaga   3540

aagtgctgga aatagcttct atatagtcag cagttcacct ggagaaagat cttaattcct   3600

tgttgttttg actaggaata tcaatatttg gtataaaata actagaatag tttattacct   3660

tttccctcat gaaattttaa atatatgcaa atatatatat cattagattc ctgtggtgga   3720

taataatttc ttcagattct aaaacaggtg tctagtgact gcttaattgt ttccaagttg   3780

catcaaagat gaattggtaa ataatggaaa tgagtagtga tatgaaaatg gttatgtaac   3840

tacatattac ttgtttctgg taatcaagtc ttatttttta aaagcctatt gtttttcaga   3900

attgagatat ttaaaacttg ttataacttc ttcctaaaaa tagaagagaa gaggaggtac   3960

tgtgtgttac aaaaattttt ttaaataaag aattcagtgt cacta                   4005


<210>  5619
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  5619

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Glu Ala Thr Phe 
65                  70                  75                  80


Cys Arg Ile Ala 



<210>  5620
<211>  1190
<212>  DNA
<213>  Homo sapiens

<400>  5620
agaaacgact acagaaagaa ctgttggctt tgcaaaatga cccacctcct ggaatgacct     60

taaatgagaa gagtgttcaa aattcaatta cacagtcatg tttactggtg aaaatattcc    120

tgttcatcct catgtttata gcaatggtca tatctgttta tccattctaa cagaagactg    180

gtccccagcg ctctcagtcc aatcagtttg tcttagcatt attagcatgc tttccagctg    240

caaggaaaag ggcaaagcag tttgtgggta caaggccttc tatgttcctg ttacgcttaa    300

agactataga aagagacgac caccggataa ttctttttat gtgcgaacat gtaacaagaa    360

tccaaagaaa acaaaatggt ggtatcatga tgatacttgt tgatgccact gttatcatcc    420

tcctagcaga agatagtcct actgagaaaa tgagcacttt gatcattcag tctttgaact    480

tactggttat agtgggaata taaataaagt gagggatcca acattacttt aaaagtcacc    540

ccaactgttt atatttggat tctatgcact gtgatcctaa ggttaacagc atgaattaac    600

atgcgtcttt aaaggactgt aatgaaagat cattgcatat ttattgaatt gtttatatct    660

actgtcaagt tgttttgaca tggaagattt tcaagtaaca ttggcagaga ggtacagtat    720

gttatcccta tggtgaaaat aaattaattt gttgtatata gttcctcaat ctctgaagta    780

aaggtatgag taatataggg tatgaatggt ttaatcaagg ctttattttg gaagtaagaa    840

aaatggcagt gatgattaaa ttgctgcagt ccataatttg ggcttgttat ttgtacatta    900

aagatttttt ccaagtaagt tacactctgt taacttcctg ctagccatca gcatgagccc    960

tactgcctaa acactatttc atttatttat gtttggaaac cccgtaaaca tttttgtttg   1020

caatcttgtt tcttttgtta taagtcaagt ttgaatgtta caatactttt attgaaactt   1080

ttgttaagtt ttttcttgta aattttcttt acttgtgagt atcatcttgt cctttaatcc   1140

tgtaccctaa aataagaaat acatttttga cagaggctta atgttttaac              1190


<210>  5621
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  5621

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Gly Lys Ala Val Cys Gly Tyr Lys Ala Phe Tyr Val Pro 
    50                  55                  60


Val Thr Leu Lys Asp Tyr Arg Lys Arg Arg Pro Pro Asp Asn Ser Phe 
65                  70                  75                  80


Tyr Val Arg Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr 
                85                  90                  95


His Asp Asp Thr Cys 
            100


<210>  5622
<211>  1615
<212>  DNA
<213>  Homo sapiens

<400>  5622
ggcctcgccg gtcttggggg gatggttcca tcatggcgtc aatgcagaaa cgactacaga     60

aagaactgtt ggctttgcaa aatgacccac ctcctggaat gaccttaaat gagaagagtg    120

ttcaaaattc aattacacag tcatgtttac tggtgaaaat attcctgttc atcctcatgt    180

ttatagcaat ggtcatatct gtttatccat tctaacagaa gactggtccc cagcgctctc    240

agtccaatca gtttgtctta gcattattag catgctttcc agctgcaagg aaaagagacg    300

accaccggat aattcttttt atgtgcgaac atgtaacaag aatccaaaga aaacaaaatg    360

gtggtatcat gccatcatgg attcgtagtc ccgcaagtcc ctgttgatct agctgttaca    420

gatcatttgt ttcttcaaaa cgagggtatt caaagatgat acttgttgat gccactgtta    480

tcatcctcct agcagaagat agtcctactg agaaaatgag cactttgatc attcagtctt    540

tgaactttaa cctttgactg gaagtgacct ataggcaatg aagactactt ccttttactg    600

catttttact cgtgtgcatt ctgggcgcat gttgatcgct ggttcagtcc aggcaactga    660

catgctttta ttagtcatac agtattaatg caggtgtcag gaaatgtcaa atataattcc    720

attttttatt tttatttttt taagcttttg gaaaagctcc aggtcctcat gtattgtgca    780

ataacaatga cttccttggc ggttttggta cgttcattgc cggcaatggg cgttgtaaca    840

ggaaaagttt tcattaactc ctgccattca atgattaatg catgataggg cctatgaaat    900

gaacttactg gttatagtgg gaatataaat aaagtgaggg atccaacatt actttaaaag    960

tcaccccaac tgtttatatt tggattctat gcactgtgat cctaaggtta acagcatgaa   1020

ttaacatgcg tctttaaagg actgtaatga aagatcattg catatttatt gaattgttta   1080

tatctactgt caagttgttt tgacatggaa gattttcaag taacattggc agagaggtac   1140

agtatgttat ccctatggtg aaaataaatt aatttgttgt atatagttcc tcaatctctg   1200

aagtaaaggt atgagtaata tagggtatga atggtttaat caaggcttta ttttggaagt   1260

aagaaaaatg gcagtgatga ttaaattgct gcagtccata atttgggctt gttatttgta   1320

cattaaagat tttttccaag taagttacac tctgttaact tcctgctagc catcagcatg   1380

agccctactg cctaaacact atttcattta tttatgtttg gaaaccccgt aaacattttt   1440

gtttgcaatc ttgtttcttt tgttataagt caagtttgaa tgttacaata cttttattga   1500

aacttttgtt aagttttttc ttgtaaattt tctttacttg tgagtatcat cttgtccttt   1560

aatcctgtac cctaaaataa gaaatacatt tttgacagag gcttaatgtt ttaac        1615


<210>  5623
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  5623

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Ala Ile Met Asp 
65                  70                  75                  80


Ser 



<210>  5624
<211>  1661
<212>  DNA
<213>  Homo sapiens

<400>  5624
gtctctggcc tcgccggtct tggggggatg gttccatcat ggcgtcaatg cagaaacgac     60

tacagaaaga actgttggct ttgcaaaatg acccacctcc tggaatgacc ttaaatgaga    120

agagtgttca aaattcaatt acacagtcat gtttactggt gaaaatattc ctgttcatcc    180

tcatgtttat agcaatggtc atatctgttt atccattcta acagaagact ggtccccagc    240

gctctcagtc caatcagttt gtcttagcat tattagcatg ctttccagct gcaaggaaaa    300

gagacgacca ccggataatt ctttttatgt gcgaacatgt aacaagaatc caaagaaaac    360

aaaatggtgg tatcatgagg caacattttg ccgtattgcc taggctggtc ttgaactcct    420

gggcccaagc agtccatcca cctcagcctc cccaaatgct ggaattacag gcgtgagcca    480

ctttgcattg ccaagaaaat tatgatactt gttgatgcca ctgttatcat cctcctagca    540

gaagatagtc ctactgagaa aatgagcact ttgatcattc agtctttgaa ctttaacctt    600

tgactggaag tgacctatag gcaatgaaga ctacttcctt ttactgcatt tttactcgtg    660

tgcattctgg gcgcatgttg atcgctggtt cagtccaggc aactgacatg cttttattag    720

tcatacagta ttaatgcagg tgtcaggaaa tgtcaaatat aattccattt tttattttta    780

tttttttaag cttttggaaa agctccaggt cctcatgtat tgtgcaataa caatgacttc    840

cttggcggtt ttggtacgtt cattgccggc aatgggcgtt gtaacaggaa aagttttcat    900

taactcctgc cattcaatga ttaatgcatg atagggccta tgaaatgaac ttactggtta    960

tagtgggaat ataaataaag tgagggatcc aacattactt taaaagtcac cccaactgtt   1020

tatatttgga ttctatgcac tgtgatccta aggttaacag catgaattaa catgcgtctt   1080

taaaggactg taatgaaaga tcattgcata tttattgaat tgtttatatc tactgtcaag   1140

ttgttttgac atggaagatt ttcaagtaac attggcagag aggtacagta tgttatccct   1200

atggtgaaaa taaattaatt tgttgtatat agttcctcaa tctctgaagt aaaggtatga   1260

gtaatatagg gtatgaatgg tttaatcaag gctttatttt ggaagtaaga aaaatggcag   1320

tgatgattaa attgctgcag tccataattt gggcttgtta tttgtacatt aaagattttt   1380

tccaagtaag ttacactctg ttaacttcct gctagccatc agcatgagcc ctactgccta   1440

aacactattt catttattta tgtttggaaa ccccgtaaac atttttgttt gcaatcttgt   1500

ttcttttgtt ataagtcaag tttgaatgtt acaatacttt tattgaaact tttgttaagt   1560

tttttcttgt aaattttctt tacttgtgag tatcatcttg tcctttaatc ctgtacccta   1620

aaataagaaa tacatttttg acagaggctt aatgttttaa c                       1661


<210>  5625
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  5625

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Glu Ala Thr Phe 
65                  70                  75                  80


Cys Arg Ile Ala 



<210>  5626
<211>  1552
<212>  DNA
<213>  Homo sapiens

<400>  5626
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagaa acgactacag aaagaactgt tggctttgca aaatgaccca cctcctggaa    120

tgaccttaaa tgagaagagt gttcaaaatt caattacaca gtcatgttta ctggtgaaaa    180

tattcctgtt catcctcatg tttatagcaa tggtcatatc tgtttatcca ttctaacaga    240

agactggtcc ccagcgctct cagtccaatc agtttgtctt agcattatta gcatgctttc    300

cagctgcaag gaaaagagac gaccaccgga taattctttt tatgtgcgaa catgtaacaa    360

gaatccaaag aaaacaaaat ggtggtatca tgatgatact tgttgatgcc actgttatca    420

tcctcctagc agaagatagt cctactgaga aaatgagcac tttgatcatt cagtctttga    480

actttaacct ttgactggaa gtgacctata ggcaatgaag actacttcct tttactgcat    540

ttttactcgt gtgcattctg ggcgcatgtt gatcgctggt tcagtccagg caactgacat    600

gcttttatta gtcatacagt attaatgcag gtgtcaggaa atgtcaaata taattccatt    660

ttttattttt atttttttaa gcttttggaa aagctccagg tcctcatgta ttgtgcaata    720

acaatgactt ccttggcggt tttggtacgt tcattgccgg caatgggcgt tgtaacagga    780

aaagttttca ttaactcctg ccattcaatg attaatgcat gatagggcct atgaaatgaa    840

cttactggtt atagtgggaa tataaataaa gtgagggatc caacattact ttaaaagtca    900

ccccaactgt ttatatttgg attctatgca ctgtgatcct aaggttaaca gcatgaatta    960

acatgcgtct ttaaaggact gtaatgaaag atcattgcat atttattgaa ttgtttatat   1020

ctactgtcaa gttgttttga catggaagat tttcaagtaa cattggcaga gaggtacagt   1080

atgttatccc tatggtgaaa ataaattaat ttgttgtata tagttcctca atctctgaag   1140

taaaggtatg agtaatatag ggtatgaatg gtttaatcaa ggctttattt tggaagtaag   1200

aaaaatggca gtgatgatta aattgctgca gtccataatt tgggcttgtt atttgtacat   1260

taaagatttt ttccaagtaa gttacactct gttaacttcc tgctagccat cagcatgagc   1320

cctactgcct aaacactatt tcatttattt atgtttggaa accccgtaaa catttttgtt   1380

tgcaatcttg tttcttttgt tataagtcaa gtttgaatgt tacaatactt ttattgaaac   1440

ttttgttaag ttttttcttg taaattttct ttacttgtga gtatcatctt gtcctttaat   1500

cctgtaccct aaaataagaa atacattttt gacagaggct taatgtttta ac           1552


<210>  5627
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  5627

Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr Ser Asn 
1               5                   10                  15


Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro Ala Leu 
            20                  25                  30


Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser Ser Cys 
        35                  40                  45


Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg Thr Cys 
    50                  55                  60


Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Asp Asp Thr Cys 
65                  70                  75                  80


<210>  5628
<211>  1655
<212>  DNA
<213>  Homo sapiens

<400>  5628
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagaa acgactacag aaagaactgt tggctttgca aaatgaccca cctcctggaa    120

tgaccttaaa tgagaagagt gttcaaaatt caattacaca gtggattgta gacatggaag    180

gtgcaccagg taccttatat gaaggggaaa aatttcaact tctatttaaa tttagtagtc    240

gatatccttt tgactctcct caggtcatgt ttactggtga aaatattcct gttcatcctc    300

atgtttatag caatggtcat atctgtttat ccattctaac agaagactgg tccccagcgc    360

tctcagtcca atcagtttgt cttagcatta ttagcatgct ttccagctgc aaggaaaaga    420

gacgaccacc ggataattct ttttatgtgc gaacatgtaa caagaatcca aagaaaacaa    480

aatggtggta tcatgatgat acttgttgat gccactgtta tcatcctcct agcagaagat    540

agtcctactg agaaaatgag cactttgatc attcagtctt tgaactttaa cctttgactg    600

gaagtgacct ataggcaatg aagactactt ccttttactg catttttact cgtgtgcatt    660

ctgggcgcat gttgatcgct ggttcagtcc aggcaactga catgctttta ttagtcatac    720

agtattaatg caggtgtcag gaaatgtcaa atataattcc attttttatt tttatttttt    780

taagcttttg gaaaagctcc aggtcctcat gtattgtgca ataacaatga cttccttggc    840

ggttttggta cgttcattgc cggcaatggg cgttgtaaca ggaaaagttt tcattaactc    900

ctgccattca atgattaatg catgataggg cctatgaaat gaacttactg gttatagtgg    960

gaatataaat aaagtgaggg atccaacatt actttaaaag tcaccccaac tgtttatatt   1020

tggattctat gcactgtgat cctaaggtta acagcatgaa ttaacatgcg tctttaaagg   1080

actgtaatga aagatcattg catatttatt gaattgttta tatctactgt caagttgttt   1140

tgacatggaa gattttcaag taacattggc agagaggtac agtatgttat ccctatggtg   1200

aaaataaatt aatttgttgt atatagttcc tcaatctctg aagtaaaggt atgagtaata   1260

tagggtatga atggtttaat caaggcttta ttttggaagt aagaaaaatg gcagtgatga   1320

ttaaattgct gcagtccata atttgggctt gttatttgta cattaaagat tttttccaag   1380

taagttacac tctgttaact tcctgctagc catcagcatg agccctactg cctaaacact   1440

atttcattta tttatgtttg gaaaccccgt aaacattttt gtttgcaatc ttgtttcttt   1500

tgttataagt caagtttgaa tgttacaata cttttattga aacttttgtt aagttttttc   1560

ttgtaaattt tctttacttg tgagtatcat cttgtccttt aatcctgtac cctaaaataa   1620

gaaatacatt tttgacagag gcttaatgtt ttaac                              1655


<210>  5629
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5629

Met Ala Ser Met Gln Lys Arg Leu Gln Lys Glu Leu Leu Ala Leu Gln 
1               5                   10                  15


Asn Asp Pro Pro Pro Gly Met Thr Leu Asn Glu Lys Ser Val Gln Asn 
            20                  25                  30


Ser Ile Thr Gln Trp Ile Val Asp Met Glu Gly Ala Pro Gly Thr Leu 
        35                  40                  45


Tyr Glu Gly Glu Lys Phe Gln Leu Leu Phe Lys Phe Ser Ser Arg Tyr 
    50                  55                  60


Pro Phe Asp Ser Pro Gln Val Met Phe Thr Gly Glu Asn Ile Pro Val 
65                  70                  75                  80


His Pro His Val Tyr Ser Asn Gly His Ile Cys Leu Ser Ile Leu Thr 
                85                  90                  95


Glu Asp Trp Ser Pro Ala Leu Ser Val Gln Ser Val Cys Leu Ser Ile 
            100                 105                 110


Ile Ser Met Leu Ser Ser Cys Lys Glu Lys Arg Arg Pro Pro Asp Asn 
        115                 120                 125


Ser Phe Tyr Val Arg Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp 
    130                 135                 140


Trp Tyr His Asp Asp Thr Cys 
145                 150


<210>  5630
<211>  1688
<212>  DNA
<213>  Homo sapiens

<400>  5630
agctcctccc cctgcgtctc tggcctcgcc ggtcttgggg ggatggttcc atcatggcgt     60

caatgcagac cacaggaagg agggtggaag tatggtttcc aaaacgacta cagaaagaac    120

tgttggcttt gcaaaatgac ccacctcctg gaatgacctt aaatgagaag agtgttcaaa    180

attcaattac acagtggatt gtagacatgg aaggtgcacc aggtacctta tatgaagggg    240

aaaaatttca acttctattt aaatttagta gtcgatatcc ttttgactct cctcaggtca    300

tgtttactgg tgaaaatatt cctgttcatc ctcatgttta tagcaatggt catatctgtt    360

tatccattct aacagaagac tggtccccag cgctctcagt ccaatcagtt tgtcttagca    420

ttattagcat gctttccagc tgcaaggaaa agagacgacc accggataat tctttttatg    480

tgcgaacatg taacaagaat ccaaagaaaa caaaatggtg gtatcatgat gatacttgtt    540

gatgccactg ttatcatcct cctagcagaa gatagtccta ctgagaaaat gagcactttg    600

atcattcagt ctttgaactt taacctttga ctggaagtga cctataggca atgaagacta    660

cttcctttta ctgcattttt actcgtgtgc attctgggcg catgttgatc gctggttcag    720

tccaggcaac tgacatgctt ttattagtca tacagtatta atgcaggtgt caggaaatgt    780

caaatataat tccatttttt atttttattt ttttaagctt ttggaaaagc tccaggtcct    840

catgtattgt gcaataacaa tgacttcctt ggcggttttg gtacgttcat tgccggcaat    900

gggcgttgta acaggaaaag ttttcattaa ctcctgccat tcaatgatta atgcatgata    960

gggcctatga aatgaactta ctggttatag tgggaatata aataaagtga gggatccaac   1020

attactttaa aagtcacccc aactgtttat atttggattc tatgcactgt gatcctaagg   1080

ttaacagcat gaattaacat gcgtctttaa aggactgtaa tgaaagatca ttgcatattt   1140

attgaattgt ttatatctac tgtcaagttg ttttgacatg gaagattttc aagtaacatt   1200

ggcagagagg tacagtatgt tatccctatg gtgaaaataa attaatttgt tgtatatagt   1260

tcctcaatct ctgaagtaaa ggtatgagta atatagggta tgaatggttt aatcaaggct   1320

ttattttgga agtaagaaaa atggcagtga tgattaaatt gctgcagtcc ataatttggg   1380

cttgttattt gtacattaaa gattttttcc aagtaagtta cactctgtta acttcctgct   1440

agccatcagc atgagcccta ctgcctaaac actatttcat ttatttatgt ttggaaaccc   1500

cgtaaacatt tttgtttgca atcttgtttc ttttgttata agtcaagttt gaatgttaca   1560

atacttttat tgaaactttt gttaagtttt ttcttgtaaa ttttctttac ttgtgagtat   1620

catcttgtcc tttaatcctg taccctaaaa taagaaatac atttttgaca gaggcttaat   1680

gttttaac                                                            1688


<210>  5631
<211>  162
<212>  PRT
<213>  Homo sapiens

<400>  5631

Met Ala Ser Met Gln Thr Thr Gly Arg Arg Val Glu Val Trp Phe Pro 
1               5                   10                  15


Lys Arg Leu Gln Lys Glu Leu Leu Ala Leu Gln Asn Asp Pro Pro Pro 
            20                  25                  30


Gly Met Thr Leu Asn Glu Lys Ser Val Gln Asn Ser Ile Thr Gln Trp 
        35                  40                  45


Ile Val Asp Met Glu Gly Ala Pro Gly Thr Leu Tyr Glu Gly Glu Lys 
    50                  55                  60


Phe Gln Leu Leu Phe Lys Phe Ser Ser Arg Tyr Pro Phe Asp Ser Pro 
65                  70                  75                  80


Gln Val Met Phe Thr Gly Glu Asn Ile Pro Val His Pro His Val Tyr 
                85                  90                  95


Ser Asn Gly His Ile Cys Leu Ser Ile Leu Thr Glu Asp Trp Ser Pro 
            100                 105                 110


Ala Leu Ser Val Gln Ser Val Cys Leu Ser Ile Ile Ser Met Leu Ser 
        115                 120                 125


Ser Cys Lys Glu Lys Arg Arg Pro Pro Asp Asn Ser Phe Tyr Val Arg 
    130                 135                 140


Thr Cys Asn Lys Asn Pro Lys Lys Thr Lys Trp Trp Tyr His Asp Asp 
145                 150                 155                 160


Thr Cys 



<210>  5632
<211>  380
<212>  DNA
<213>  Homo sapiens

<400>  5632
aaaaaaaaaa tctggacata cccaagctgt gtatgtgcct gagatcttcc cttccaagtg     60

atttattaaa ctgggaagtc agaagcagtc ctgtgaacat ttgtttgttg aagcatgaaa    120

aggcagaatt gatgagtcct tgcttgagtc tatgcctcca cccagtagtt tgttcttagt    180

ctcctagggg ctgatctcag cagagaaatg gagacagttc agtcaccaac agtttgttac    240

tggattttgg aaaaggtacc aaagtaagaa tccaaggctt gtattcttat cttagctctg    300

tgattaacaa gcttaggtaa ggcttctaat ctttctgggt ttctttcctt atcaataaaa    360

tgcgcaagtc agactgcata                                                380


<210>  5633
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  5633

Met Cys Leu Arg Ser Ser Leu Pro Ser Asp Leu Leu Asn Trp Glu Val 
1               5                   10                  15


Arg Ser Ser Pro Val Asn Ile Cys Leu Leu Lys His Glu Lys Ala Glu 
            20                  25                  30


Leu Met Ser Pro Cys Leu Ser Leu Cys Leu His Pro Val Val Cys Ser 
        35                  40                  45


<210>  5634
<211>  2075
<212>  DNA
<213>  Homo sapiens

<400>  5634
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tatttaatac ctgtagttca gttagtaact ttttcatata    660

tagcatgttg cctgtatgca gttgaactat ataaagttca ttgcaaagca gattatcttg    720

tttttttgca tagcaatcaa agttgaaatt tgtttgctac atcaacaaat taaggacatt    780

ttcacaaact gagaaataaa caaatatgcc aattcgtagg tggttttgcc ttatcctttg    840

aatgtgactt aaaatcagca atgatgatat agtaaatact gaaatttagg tgtaaatcaa    900

tacgttctac agggaaataa tgaggctaag tatttttatg tttttagtgg ttttttagaa    960

acctaatctt atagccgcca ttagcattac tagagttatg caaataattg cattataaac   1020

atgtttataa cttagccaaa acattgattt ttataactct ccaagtatga gttgaaattt   1080

cttatgtctt ttgataaact gcagtattct ttaagtgtac tttgtccttt tgtttattgc   1140

tacaatttaa gaactttatt taaaaacaat tttggaaggt tactaggtac agcttttgca   1200

gaagaaactg aactgtagcc agatggtcag caagtaaact acatgactta gagttcttgt   1260

gcattataca ttttgggtaa ttcaaagtac tgtatttgca ttgactataa agcgtcgttt   1320

gcaatattta ttcttccttc atagtccctt gttgtgatta tacttccagt tgtttaaatg   1380

tattttaaaa gactcactat taactttatt cagatcttaa aagctacacc tttttgaact   1440

attccagtct ttctccatcc aattagaatg ttatggaata acatgtgaag agatacagtg   1500

aaaatcatat tataatgcat tgaagatatc ctacatgaat tatcttctat taaaatatgt   1560

cccaataaat atacccataa tcagtgggtc ttctactgaa atcaagctca ttcagctttt   1620

ctattaagca gccaaaaaat tttttgaaaa aatatgacag catcattcct tatgcatggg   1680

gaaagaagca ctggagatgg gtttagtatt gtctttatct cagaggtgga acaaagttgt   1740

cattataggg tctataaact taagtctcca gcttatttga gactggctta atatggctga   1800

gcccggtggc tcatgcctgt aatcccagca ctttcagagg acgaggcggg tagatcactt   1860

gaggccagga gtttgagacc agcctggcca ccatggcaaa accccatctc taccaaaaat   1920

gcaaaaatta gctaggccat ggtggcacac gcctgtaatc ccagctactt gtgaggctga   1980

ggcatgagaa tcgcttgaac ctgggaggtg gaggtggcag tgagccgaga tcgcaccact   2040

gcactccagc ctgggtgaca gagcgagact gtctc                              2075


<210>  5635
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5635

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5636
<211>  1923
<212>  DNA
<213>  Homo sapiens

<400>  5636
cagacggaag tgagcgacac actctgcgtc ctcgcctcac caggaaacta ctaaagttcc     60

tggggaagca aagtagaatt tcataagaac aaaatggatg gagaggagaa aacctatggt    120

ggctgtgaag gacctgatgc catgtatgtc aaattgatat catctgatgg ccatgaattt    180

attgtaaaaa gagaacatgc attaacatca ggcacgataa aagccatgtt gagtggccca    240

ggtcagtttg ctgagaacga aaccaatgag gtcaatttta gagagatacc ttcacatgtg    300

ctatcgaaag tatgcatgta ttttacgtac aaggttcgct acactaacag ctccaccgag    360

attcctgaat tcccaattgc acctgaaatt gcactggaac tgctgatggc tgcgaacttc    420

ttagattgtt aaataaaata aattataata aactgttaac tcttttcagt atttaatacc    480

tgtagttcag ttagtaactt tttcatatat agcatgttgc ctgtatgcag ttgaactata    540

taaagttcat tgcaaagcag attatcttgt ttttttgcat agcaatcaaa gttgaaattt    600

gtttgctaca tcaacaaatt aaggacattt tcacaaactg agaaataaac aaatatgcca    660

attcgtaggt ggttttgcct tatcctttga atgtgactta aaatcagcaa tgatgatata    720

gtaaatactg aaatttaggt gtaaatcaat acgttctaca gggaaataat gaggctaagt    780

atttttatgt ttttagtggt tttttagaaa cctaatctta tagccgccat tagcattact    840

agagttatgc aaataattgc attataaaca tgtttataac ttagccaaaa cattgatttt    900

tataactctc caagtatgag ttgaaatttc ttatgtcttt tgataaactg cagtattctt    960

taagtgtact ttgtcctttt gtttattgct acaatttaag aactttattt aaaaacaatt   1020

ttggaaggtt actaggtaca gcttttgcag aagaaactga actgtagcca gatggtcagc   1080

aagtaaacta catgacttag agttcttgtg cattatacat tttgggtaat tcaaagtact   1140

gtatttgcat tgactataaa gcgtcgtttg caatatttat tcttccttca tagtcccttg   1200

ttgtgattat acttccagtt gtttaaatgt attttaaaag actcactatt aactttattc   1260

agatcttaaa agctacacct ttttgaacta ttccagtctt tctccatcca attagaatgt   1320

tatggaataa catgtgaaga gatacagtga aaatcatatt ataatgcatt gaagatatcc   1380

tacatgaatt atcttctatt aaaatatgtc ccaataaata tacccataat cagtgggtct   1440

tctactgaaa tcaagctcat tcagcttttc tattaagcag ccaaaaaatt ttttgaaaaa   1500

atatgacagc atcattcctt atgcatgggg aaagaagcac tggagatggg tttagtattg   1560

tctttatctc agaggtggaa caaagttgtc attatagggt ctataaactt aagtctccag   1620

cttatttgag actggcttaa tatggctgag cccggtggct catgcctgta atcccagcac   1680

tttcagagga cgaggcgggt agatcacttg aggccaggag tttgagacca gcctggccac   1740

catggcaaaa ccccatctct accaaaaatg caaaaattag ctaggccatg gtggcacacg   1800

cctgtaatcc cagctacttg tgaggctgag gcatgagaat cgcttgaacc tgggaggtgg   1860

aggtggcagt gagccgagat cgcaccactg cactccagcc tgggtgacag agcgagactg   1920

tct                                                                 1923


<210>  5637
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5637

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5638
<211>  1325
<212>  DNA
<213>  Homo sapiens

<400>  5638
agagacagag tctcattctg ttgcccaggc tggagtgcaa tggtgcggtc tcagctcact     60

gcaatctccg cctgctgggt tcaggcaatt ctcctgcctc agagtagctg gaattacagg    120

tcagtttgct gagaacgaaa ccaatgaggt caattttaga gagatacctt cacatgtgct    180

atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac actaacagct ccaccgagat    240

tcctgaattc ccaattgcac ctgaaattgc actggaactg ctgatggctg cgaacttctt    300

agattgttaa ataaaataaa ttataataaa ctgttaactc ttttcagtat ttaatacctg    360

tagttcagtt agtaactttt tcatatatag catgttgcct gtatgcagtt gaactatata    420

aagttcattg caaagcagat tatcttgttt ttttgcatag caatcaaagt tgaaatttgt    480

ttgctacatc aacaaattaa ggacattttc acaaactgag aaataaacaa atatgccaat    540

tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa atcagcaatg atgatatagt    600

aaatactgaa atttaggtgt aaatcaatac gttctacagg gaaataatga ggctaagtat    660

ttttatgttt ttagtggttt tttagaaacc taatcttata gccgccatta gcattactag    720

agttatgcaa ataattgcat tataaacatg tttataactt agccaaaaca ttgattttta    780

taactctcca agtatgagtt gaaatttctt atgtcttttg ataaactgca gtattcttta    840

agtgtacttt gtccttttgt ttattgctac aatttaagaa ctttatttaa aaacaatttt    900

ggaaggttac taggtacagc ttttgcagaa gaaactgaac tgtagccaga tggtcagcaa    960

gtaaactaca tgacttagag ttcttgtgca ttatacattt tgggtaattc aaagtactgt   1020

atttgcattg actataaagc gtcgtttgca atatttattc ttccttcata gtcccttgtt   1080

gtgattatac ttccagttgt ttaaatgtat tttaaaagac tcactattaa ctttattcag   1140

atcttaaaag ctacaccttt ttgaactatt ccagtctttc tccatccaat tagaatgtta   1200

tggaataaca tgtgaagaga tacagtgaaa atcatattat aatgcattga agatatccta   1260

catgaattat cttctattaa aatatgtccc aataaatata cccataatca gtgggtcttc   1320

tactg                                                               1325


<210>  5639
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5639

Met Val Arg Ser Gln Leu Thr Ala Ile Ser Ala Cys Trp Val Gln Ala 
1               5                   10                  15


Ile Leu Leu Pro Gln Ser Ser Trp Asn Tyr Arg Ser Val Cys 
            20                  25                  30


<210>  5640
<211>  1516
<212>  DNA
<213>  Homo sapiens

<400>  5640
tgttagcatt tgcatagcta gaaaatttgg gttaatttta ttaccgatgt cactttcaaa     60

agcttaatta ggcagaaaac catcctagag tgatgatatc tttggagtta aggaaactac    120

taaagttcct ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa    180

acctatggtg gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc    240

catgaattta ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg    300

agtggcccag gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct    360

tcacatgtgc tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc    420

tccaccgaga ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct    480

gcgaacttct tagattgtta aataaaataa attataataa actgttaact cttttcagta    540

tttaatacct gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt    600

tgaactatat aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag    660

ttgaaatttg tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca    720

aatatgccaa ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat    780

gatgatatag taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg    840

aggctaagta tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt    900

agcattacta gagttatgca aataattgca ttataaacat gtttataact tagccaaaac    960

attgattttt ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc   1020

agtattcttt aagtgtactt tgtccttttg tttattgcta caatttaaga actttattta   1080

aaaacaattt tggaaggtta ctaggtacag cttttgcaga agaaactgaa ctgtagccag   1140

atggtcagca agtaaactac atgacttaga gttcttgtgc attatacatt ttgggtaatt   1200

caaagtactg tatttgcatt gactataaag cgtcgtttgc aatatttatt cttccttcat   1260

agtcccttgt tgtgattata cttccagttg tttaaatgta ttttaaaaga ctcactatta   1320

actttattca gatcttaaaa gctacacctt tttgaactat tccagtcttt ctccatccaa   1380

ttagaatgtt atggaataac atgtgaagag atacagtgaa aatcatatta taatgcattg   1440

aagatatcct acatgaatta tcttctatta aaatatgtcc caataaatat acccataatc   1500

agtgggtctt ctactg                                                   1516


<210>  5641
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5641

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5642
<211>  1461
<212>  DNA
<213>  Homo sapiens

<400>  5642
gcagtttaca tgtggattta ttcattctgg agatacaatg gcaaggaaac agctgtggaa     60

actactaaag ttcctgggga agcaaagtag aatttcataa gaacaaaatg gatggagagg    120

agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg atatcatctg    180

atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg ataaaagcca    240

tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat tttagagaga    300

taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt cgctacacta    360

acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg gaactgctga    420

tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt taactctttt    480

cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg ttgcctgtat    540

gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt gcatagcaat    600

caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa actgagaaat    660

aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga cttaaaatca    720

gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc tacagggaaa    780

taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat cttatagccg    840

ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta taacttagcc    900

aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt cttttgataa    960

actgcagtat tctttaagtg tactttgtcc ttttgtttat tgctacaatt taagaacttt   1020

atttaaaaac aattttggaa ggttactagg tacagctttt gcagaagaaa ctgaactgta   1080

gccagatggt cagcaagtaa actacatgac ttagagttct tgtgcattat acattttggg   1140

taattcaaag tactgtattt gcattgacta taaagcgtcg tttgcaatat ttattcttcc   1200

ttcatagtcc cttgttgtga ttatacttcc agttgtttaa atgtatttta aaagactcac   1260

tattaacttt attcagatct taaaagctac acctttttga actattccag tctttctcca   1320

tccaattaga atgttatgga ataacatgtg aagagataca gtgaaaatca tattataatg   1380

cattgaagat atcctacatg aattatcttc tattaaaata tgtcccaata aatataccca   1440

taatcagtgg gtcttctact g                                             1461


<210>  5643
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5643

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5644
<211>  1638
<212>  DNA
<213>  Homo sapiens

<400>  5644
gggagaagag ggcggcggga cctttcctgg cgccgctcgc agtttacatg tggatttatt     60

cattctggag atacaatggc aaggaaacag ctgtgagtct tgctgtgtgg cccaggctgg    120

agtgcccggc tggtctcaaa ttcctgacct caagtgatct ccctcccaaa gtgttgcgat    180

tgcaggtgtg agccactgca cctggctgct gagaaatctt tgcctacagt gagggaaact    240

actaaagttc ctggggaagc aaagtagaat ttcataagaa caaaatggat ggagaggaga    300

aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt caaattgata tcatctgatg    360

gccatgaatt tattgtaaaa agagaacatg cattaacatc aggcacgata aaagccatgt    420

tgagtggccc aggtcagttt gctgagaacg aaaccaatga ggtcaatttt agagagatac    480

cttcacatgt gctatcgaaa gtatgcatgt attttacgta caaggttcgc tacactaaca    540

gctccaccga gattcctgaa ttcccaattg cacctgaaat tgcactggaa ctgctgatgg    600

ctgcgaactt cttagattgt taaataaaat aaattataat aaactgttaa ctcttttcag    660

tatttaatac ctgtagttca gttagtaact ttttcatata tagcatgttg cctgtatgca    720

gttgaactat ataaagttca ttgcaaagca gattatcttg tttttttgca tagcaatcaa    780

agttgaaatt tgtttgctac atcaacaaat taaggacatt ttcacaaact gagaaataaa    840

caaatatgcc aattcgtagg tggttttgcc ttatcctttg aatgtgactt aaaatcagca    900

atgatgatat agtaaatact gaaatttagg tgtaaatcaa tacgttctac agggaaataa    960

tgaggctaag tatttttatg tttttagtgg ttttttagaa acctaatctt atagccgcca   1020

ttagcattac tagagttatg caaataattg cattataaac atgtttataa cttagccaaa   1080

acattgattt ttataactct ccaagtatga gttgaaattt cttatgtctt ttgataaact   1140

gcagtattct ttaagtgtac tttgtccttt tgtttattgc tacaatttaa gaactttatt   1200

taaaaacaat tttggaaggt tactaggtac agcttttgca gaagaaactg aactgtagcc   1260

agatggtcag caagtaaact acatgactta gagttcttgt gcattataca ttttgggtaa   1320

ttcaaagtac tgtatttgca ttgactataa agcgtcgttt gcaatattta ttcttccttc   1380

atagtccctt gttgtgatta tacttccagt tgtttaaatg tattttaaaa gactcactat   1440

taactttatt cagatcttaa aagctacacc tttttgaact attccagtct ttctccatcc   1500

aattagaatg ttatggaata acatgtgaag agatacagtg aaaatcatat tataatgcat   1560

tgaagatatc ctacatgaat tatcttctat taaaatatgt cccaataaat atacccataa   1620

tcagtgggtc ttctactg                                                 1638


<210>  5645
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5645

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5646
<211>  1469
<212>  DNA
<213>  Homo sapiens

<400>  5646
acccggctgc ggtggctgcg ggactgacga gtgagtctcg ggctggggcg gaaacggagc     60

tccgggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga acaaaatgga    120

tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg tcaaattgat    180

atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat caggcacgat    240

aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg aggtcaattt    300

tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt acaaggttcg    360

ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa ttgcactgga    420

actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa taaactgtta    480

actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat atagcatgtt    540

gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt gtttttttgc    600

atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat tttcacaaac    660

tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt gaatgtgact    720

taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca atacgttcta    780

cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga aacctaatct    840

tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa catgtttata    900

acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt tcttatgtct    960

tttgataaac tgcagtattc tttaagtgta ctttgtcctt ttgtttattg ctacaattta   1020

agaactttat ttaaaaacaa ttttggaagg ttactaggta cagcttttgc agaagaaact   1080

gaactgtagc cagatggtca gcaagtaaac tacatgactt agagttcttg tgcattatac   1140

attttgggta attcaaagta ctgtatttgc attgactata aagcgtcgtt tgcaatattt   1200

attcttcctt catagtccct tgttgtgatt atacttccag ttgtttaaat gtattttaaa   1260

agactcacta ttaactttat tcagatctta aaagctacac ctttttgaac tattccagtc   1320

tttctccatc caattagaat gttatggaat aacatgtgaa gagatacagt gaaaatcata   1380

ttataatgca ttgaagatat cctacatgaa ttatcttcta ttaaaatatg tcccaataaa   1440

tatacccata atcagtgggt cttctactg                                     1469


<210>  5647
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5647

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5648
<211>  1674
<212>  DNA
<213>  Homo sapiens

<400>  5648
cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat tctttcgact gccccggaac     60

ccaccggagc aggcagctgg gggtgggggg gcggccctgg gataggggct gtggcagtac    120

gcggggaccc ggctgcggtg gctgcgggac tgacgagatc atcagggaag gaagacctct    180

ctgaggagtt gatgttttac ctggagacct aaatgatgag gatttaaaag cttttcggac    240

aacagcaatt acaaatgcaa agaccttgag gaaactacta aagttcctgg ggaagcaaag    300

tagaatttca taagaacaaa atggatggag aggagaaaac ctatggtggc tgtgaaggac    360

ctgatgccat gtatgtcaaa ttgatatcat ctgatggcca tgaatttatt gtaaaaagag    420

aacatgcatt aacatcaggc acgataaaag ccatgttgag tggcccaggt cagtttgctg    480

agaacgaaac caatgaggtc aattttagag agataccttc acatgtgcta tcgaaagtat    540

gcatgtattt tacgtacaag gttcgctaca ctaacagctc caccgagatt cctgaattcc    600

caattgcacc tgaaattgca ctggaactgc tgatggctgc gaacttctta gattgttaaa    660

taaaataaat tataataaac tgttaactct tttcagtatt taatacctgt agttcagtta    720

gtaacttttt catatatagc atgttgcctg tatgcagttg aactatataa agttcattgc    780

aaagcagatt atcttgtttt tttgcatagc aatcaaagtt gaaatttgtt tgctacatca    840

acaaattaag gacattttca caaactgaga aataaacaaa tatgccaatt cgtaggtggt    900

tttgccttat cctttgaatg tgacttaaaa tcagcaatga tgatatagta aatactgaaa    960

tttaggtgta aatcaatacg ttctacaggg aaataatgag gctaagtatt tttatgtttt   1020

tagtggtttt ttagaaacct aatcttatag ccgccattag cattactaga gttatgcaaa   1080

taattgcatt ataaacatgt ttataactta gccaaaacat tgatttttat aactctccaa   1140

gtatgagttg aaatttctta tgtcttttga taaactgcag tattctttaa gtgtactttg   1200

tccttttgtt tattgctaca atttaagaac tttatttaaa aacaattttg gaaggttact   1260

aggtacagct tttgcagaag aaactgaact gtagccagat ggtcagcaag taaactacat   1320

gacttagagt tcttgtgcat tatacatttt gggtaattca aagtactgta tttgcattga   1380

ctataaagcg tcgtttgcaa tatttattct tccttcatag tcccttgttg tgattatact   1440

tccagttgtt taaatgtatt ttaaaagact cactattaac tttattcaga tcttaaaagc   1500

tacacctttt tgaactattc cagtctttct ccatccaatt agaatgttat ggaataacat   1560

gtgaagagat acagtgaaaa tcatattata atgcattgaa gatatcctac atgaattatc   1620

ttctattaaa atatgtccca ataaatatac ccataatcag tgggtcttct actg         1674


<210>  5649
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5649

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5650
<211>  1719
<212>  DNA
<213>  Homo sapiens

<400>  5650
ctcaccaggt acggatctcc cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat     60

tctttcgact gccccggaac ccaccggagc aggcagctgg gggtgggggg gcggccctgg    120

gataggggct gtggcagtac gcggggaccc ggctgcggtg gctgcgggac tgacgaagtc    180

ttgctgtgtg gcccaggctg gagtgcccgg ctggtctcaa attcctgacc tcaagtgatc    240

tccctcccaa agtgttgcga ttgcaggtgt gagccactgc acctggctgc tgagaaatct    300

ttgcctacag tgagggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga    360

acaaaatgga tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg    420

tcaaattgat atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat    480

caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg    540

aggtcaattt tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt    600

acaaggttcg ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa    660

ttgcactgga actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa    720

taaactgtta actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat    780

atagcatgtt gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt    840

gtttttttgc atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat    900

tttcacaaac tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt    960

gaatgtgact taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca   1020

atacgttcta cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga   1080

aacctaatct tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa   1140

catgtttata acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt   1200

tcttatgtct tttgataaac tgcagtattc tttaagtgta ctttgtcctt ttgtttattg   1260

ctacaattta agaactttat ttaaaaacaa ttttggaagg ttactaggta cagcttttgc   1320

agaagaaact gaactgtagc cagatggtca gcaagtaaac tacatgactt agagttcttg   1380

tgcattatac attttgggta attcaaagta ctgtatttgc attgactata aagcgtcgtt   1440

tgcaatattt attcttcctt catagtccct tgttgtgatt atacttccag ttgtttaaat   1500

gtattttaaa agactcacta ttaactttat tcagatctta aaagctacac ctttttgaac   1560

tattccagtc tttctccatc caattagaat gttatggaat aacatgtgaa gagatacagt   1620

gaaaatcata ttataatgca ttgaagatat cctacatgaa ttatcttcta ttaaaatatg   1680

tcccaataaa tatacccata atcagtgggt cttctactg                          1719


<210>  5651
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5651

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5652
<211>  1531
<212>  DNA
<213>  Homo sapiens

<400>  5652
ctcgcctcac caggtacgga tctcccgcgc gtcgccgaaa gcggctctga cccagcggaa     60

gtaattcttt cgactgcccc ggaacccacc ggagcaggca gctgggggtg ggggggcggc    120

cctgggatag gggctgtggc agtacgcggg gacccggctg cggtggctgc gggactgacg    180

aatggagagg agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg    240

atatcatctg atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg    300

ataaaagcca tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat    360

tttagagaga taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt    420

cgctacacta acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg    480

gaactgctga tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt    540

taactctttt cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg    600

ttgcctgtat gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt    660

gcatagcaat caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa    720

actgagaaat aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga    780

cttaaaatca gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc    840

tacagggaaa taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat    900

cttatagccg ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta    960

taacttagcc aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt   1020

cttttgataa actgcagtat tctttaagtg tactttgtcc ttttgtttat tgctacaatt   1080

taagaacttt atttaaaaac aattttggaa ggttactagg tacagctttt gcagaagaaa   1140

ctgaactgta gccagatggt cagcaagtaa actacatgac ttagagttct tgtgcattat   1200

acattttggg taattcaaag tactgtattt gcattgacta taaagcgtcg tttgcaatat   1260

ttattcttcc ttcatagtcc cttgttgtga ttatacttcc agttgtttaa atgtatttta   1320

aaagactcac tattaacttt attcagatct taaaagctac acctttttga actattccag   1380

tctttctcca tccaattaga atgttatgga ataacatgtg aagagataca gtgaaaatca   1440

tattataatg cattgaagat atcctacatg aattatcttc tattaaaata tgtcccaata   1500

aatataccca taatcagtgg gtcttctact g                                  1531


<210>  5653
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5653

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5654
<211>  1598
<212>  DNA
<213>  Homo sapiens

<400>  5654
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tatttaatac ctgtagttca gttagtaact ttttcatata    660

tagcatgttg cctgtatgca gttgaactat ataaagttca ttgcaaagca gattatcttg    720

tttttttgca tagcaatcaa agttgaaatt tgtttgctac atcaacaaat taaggacatt    780

ttcacaaact gagaaataaa caaatatgcc aattcgtagg tggttttgcc ttatcctttg    840

aatgtgactt aaaatcagca atgatgatat agtaaatact gaaatttagg tgtaaatcaa    900

tacgttctac agggaaataa tgaggctaag tatttttatg tttttagtgg ttttttagaa    960

acctaatctt atagccgcca ttagcattac tagagttatg caaataattg cattataaac   1020

atgtttataa cttagccaaa acattgattt ttataactct ccaagtatga gttgaaattt   1080

cttatgtctt ttgataaact gcagtattct ttaagtgtac tttgtccttt tgtttattgc   1140

tacaatttaa gaactttatt taaaaacaat tttggaaggt tactaggtac agcttttgca   1200

gaagaaactg aactgtagcc agatggtcag caagtaaact acatgactta gagttcttgt   1260

gcattataca ttttgggtaa ttcaaagtac tgtatttgca ttgactataa agcgtcgttt   1320

gcaatattta ttcttccttc atagtccctt gttgtgatta tacttccagt tgtttaaatg   1380

tattttaaaa gactcactat taactttatt cagatcttaa aagctacacc tttttgaact   1440

attccagtct ttctccatcc aattagaatg ttatggaata acatgtgaag agatacagtg   1500

aaaatcatat tataatgcat tgaagatatc ctacatgaat tatcttctat taaaatatgt   1560

cccaataaat atacccataa tcagtgggtc ttctactg                           1598


<210>  5655
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5655

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5656
<211>  1392
<212>  DNA
<213>  Homo sapiens

<400>  5656
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agatggagag gagaaaacct     60

atggtggctg tgaaggacct gatgccatgt atgtcaaatt gatatcatct gatggccatg    120

aatttattgt aaaaagagaa catgcattaa catcaggcac gataaaagcc atgttgagtg    180

gcccaggtca gtttgctgag aacgaaacca atgaggtcaa ttttagagag ataccttcac    240

atgtgctatc gaaagtatgc atgtatttta cgtacaaggt tcgctacact aacagctcca    300

ccgagattcc tgaattccca attgcacctg aaattgcact ggaactgctg atggctgcga    360

acttcttaga ttgttaaata aaataaatta taataaactg ttaactcttt tcagtattta    420

atacctgtag ttcagttagt aactttttca tatatagcat gttgcctgta tgcagttgaa    480

ctatataaag ttcattgcaa agcagattat cttgtttttt tgcatagcaa tcaaagttga    540

aatttgtttg ctacatcaac aaattaagga cattttcaca aactgagaaa taaacaaata    600

tgccaattcg taggtggttt tgccttatcc tttgaatgtg acttaaaatc agcaatgatg    660

atatagtaaa tactgaaatt taggtgtaaa tcaatacgtt ctacagggaa ataatgaggc    720

taagtatttt tatgttttta gtggtttttt agaaacctaa tcttatagcc gccattagca    780

ttactagagt tatgcaaata attgcattat aaacatgttt ataacttagc caaaacattg    840

atttttataa ctctccaagt atgagttgaa atttcttatg tcttttgata aactgcagta    900

ttctttaagt gtactttgtc cttttgttta ttgctacaat ttaagaactt tatttaaaaa    960

caattttgga aggttactag gtacagcttt tgcagaagaa actgaactgt agccagatgg   1020

tcagcaagta aactacatga cttagagttc ttgtgcatta tacattttgg gtaattcaaa   1080

gtactgtatt tgcattgact ataaagcgtc gtttgcaata tttattcttc cttcatagtc   1140

ccttgttgtg attatacttc cagttgttta aatgtatttt aaaagactca ctattaactt   1200

tattcagatc ttaaaagcta cacctttttg aactattcca gtctttctcc atccaattag   1260

aatgttatgg aataacatgt gaagagatac agtgaaaatc atattataat gcattgaaga   1320

tatcctacat gaattatctt ctattaaaat atgtcccaat aaatataccc ataatcagtg   1380

ggtcttctac tg                                                       1392


<210>  5657
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5657

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5658
<211>  1585
<212>  DNA
<213>  Homo sapiens

<400>  5658
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agagtcttgc tgtgtggccc     60

aggctggagt gcccggctgg tctcaaattc ctgacctcaa gtgatctccc tcccaaagtg    120

ttgcgattgc aggtgtgagc cactgcacct ggctgctgag aaatctttgc ctacagtgag    180

ggaaactact aaagttcctg gggaagcaaa gtagaatttc ataagaacaa aatggatgga    240

gaggagaaaa cctatggtgg ctgtgaagga cctgatgcca tgtatgtcaa attgatatca    300

tctgatggcc atgaatttat tgtaaaaaga gaacatgcat taacatcagg cacgataaaa    360

gccatgttga gtggcccagg tcagtttgct gagaacgaaa ccaatgaggt caattttaga    420

gagatacctt cacatgtgct atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac    480

actaacagct ccaccgagat tcctgaattc ccaattgcac ctgaaattgc actggaactg    540

ctgatggctg cgaacttctt agattgttaa ataaaataaa ttataataaa ctgttaactc    600

ttttcagtat ttaatacctg tagttcagtt agtaactttt tcatatatag catgttgcct    660

gtatgcagtt gaactatata aagttcattg caaagcagat tatcttgttt ttttgcatag    720

caatcaaagt tgaaatttgt ttgctacatc aacaaattaa ggacattttc acaaactgag    780

aaataaacaa atatgccaat tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa    840

atcagcaatg atgatatagt aaatactgaa atttaggtgt aaatcaatac gttctacagg    900

gaaataatga ggctaagtat ttttatgttt ttagtggttt tttagaaacc taatcttata    960

gccgccatta gcattactag agttatgcaa ataattgcat tataaacatg tttataactt   1020

agccaaaaca ttgattttta taactctcca agtatgagtt gaaatttctt atgtcttttg   1080

ataaactgca gtattcttta agtgtacttt gtccttttgt ttattgctac aatttaagaa   1140

ctttatttaa aaacaatttt ggaaggttac taggtacagc ttttgcagaa gaaactgaac   1200

tgtagccaga tggtcagcaa gtaaactaca tgacttagag ttcttgtgca ttatacattt   1260

tgggtaattc aaagtactgt atttgcattg actataaagc gtcgtttgca atatttattc   1320

ttccttcata gtcccttgtt gtgattatac ttccagttgt ttaaatgtat tttaaaagac   1380

tcactattaa ctttattcag atcttaaaag ctacaccttt ttgaactatt ccagtctttc   1440

tccatccaat tagaatgtta tggaataaca tgtgaagaga tacagtgaaa atcatattat   1500

aatgcattga agatatccta catgaattat cttctattaa aatatgtccc aataaatata   1560

cccataatca gtgggtcttc tactg                                         1585


<210>  5659
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5659

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5660
<211>  1446
<212>  DNA
<213>  Homo sapiens

<400>  5660
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc aggaaactac taaagttcct     60

ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa acctatggtg    120

gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc catgaattta    180

ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg agtggcccag    240

gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct tcacatgtgc    300

tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc tccaccgaga    360

ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct gcgaacttct    420

tagattgtta aataaaataa attataataa actgttaact cttttcagta tttaatacct    480

gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt tgaactatat    540

aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag ttgaaatttg    600

tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca aatatgccaa    660

ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat gatgatatag    720

taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg aggctaagta    780

tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt agcattacta    840

gagttatgca aataattgca ttataaacat gtttataact tagccaaaac attgattttt    900

ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc agtattcttt    960

aagtgtactt tgtccttttg tttattgcta caatttaaga actttattta aaaacaattt   1020

tggaaggtta ctaggtacag cttttgcaga agaaactgaa ctgtagccag atggtcagca   1080

agtaaactac atgacttaga gttcttgtgc attatacatt ttgggtaatt caaagtactg   1140

tatttgcatt gactataaag cgtcgtttgc aatatttatt cttccttcat agtcccttgt   1200

tgtgattata cttccagttg tttaaatgta ttttaaaaga ctcactatta actttattca   1260

gatcttaaaa gctacacctt tttgaactat tccagtcttt ctccatccaa ttagaatgtt   1320

atggaataac atgtgaagag atacagtgaa aatcatatta taatgcattg aagatatcct   1380

acatgaatta tcttctatta aaatatgtcc caataaatat acccataatc agtgggtctt   1440

ctactg                                                              1446


<210>  5661
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5661

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5662
<211>  1064
<212>  DNA
<213>  Homo sapiens

<400>  5662
agagacagag tctcattctg ttgcccaggc tggagtgcaa tggtgcggtc tcagctcact     60

gcaatctccg cctgctgggt tcaggcaatt ctcctgcctc agagtagctg gaattacagg    120

tcagtttgct gagaacgaaa ccaatgaggt caattttaga gagatacctt cacatgtgct    180

atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac actaacagct ccaccgagat    240

tcctgaattc ccaattgcac ctgaaattgc actggaactg ctgatggctg cgaacttctt    300

agattgttaa ataaaataaa ttataataaa ctgttaactc ttttcagtat ttaatacctg    360

tagttcagtt agtaactttt tcatatatag catgttgcct gtatgcagtt gaactatata    420

aagttcattg caaagcagat tatcttgttt ttttgcatag caatcaaagt tgaaatttgt    480

ttgctacatc aacaaattaa ggacattttc acaaactgag aaataaacaa atatgccaat    540

tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa atcagcaatg atgatatagt    600

aaatactgaa atttaggtgt aaatcaatac gttctacagg gaaataatga ggctaagtat    660

ttttatgttt ttagtggttt tttagaaacc taatcttata gccgccatta gcattactag    720

agttatgcaa ataattgcat tataaacatg tttataactt agccaaaaca ttgattttta    780

taactctcca agtatgagtt gaaatttctt atgtcttttg ataaactgca gtattcttta    840

agtgtacttt gtccttttgt ttattgctac aatttaagaa ctttatttaa aaacaatttt    900

ggaaggttac taggtacagc ttttgcagaa gaaactgaac tgtagccaga tggtcagcaa    960

gtaaactaca tgacttagag ttcttgtgca ttatacattt tgggtaattc aaagtactgt   1020

atttgcattg actataaagc gtcgtttgca atatttattc ttcc                    1064


<210>  5663
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5663

Met Val Arg Ser Gln Leu Thr Ala Ile Ser Ala Cys Trp Val Gln Ala 
1               5                   10                  15


Ile Leu Leu Pro Gln Ser Ser Trp Asn Tyr Arg Ser Val Cys 
            20                  25                  30


<210>  5664
<211>  1255
<212>  DNA
<213>  Homo sapiens

<400>  5664
tgttagcatt tgcatagcta gaaaatttgg gttaatttta ttaccgatgt cactttcaaa     60

agcttaatta ggcagaaaac catcctagag tgatgatatc tttggagtta aggaaactac    120

taaagttcct ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa    180

acctatggtg gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc    240

catgaattta ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg    300

agtggcccag gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct    360

tcacatgtgc tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc    420

tccaccgaga ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct    480

gcgaacttct tagattgtta aataaaataa attataataa actgttaact cttttcagta    540

tttaatacct gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt    600

tgaactatat aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag    660

ttgaaatttg tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca    720

aatatgccaa ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat    780

gatgatatag taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg    840

aggctaagta tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt    900

agcattacta gagttatgca aataattgca ttataaacat gtttataact tagccaaaac    960

attgattttt ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc   1020

agtattcttt aagtgtactt tgtccttttg tttattgcta caatttaaga actttattta   1080

aaaacaattt tggaaggtta ctaggtacag cttttgcaga agaaactgaa ctgtagccag   1140

atggtcagca agtaaactac atgacttaga gttcttgtgc attatacatt ttgggtaatt   1200

caaagtactg tatttgcatt gactataaag cgtcgtttgc aatatttatt cttcc        1255


<210>  5665
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5665

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5666
<211>  1200
<212>  DNA
<213>  Homo sapiens

<400>  5666
gcagtttaca tgtggattta ttcattctgg agatacaatg gcaaggaaac agctgtggaa     60

actactaaag ttcctgggga agcaaagtag aatttcataa gaacaaaatg gatggagagg    120

agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg atatcatctg    180

atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg ataaaagcca    240

tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat tttagagaga    300

taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt cgctacacta    360

acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg gaactgctga    420

tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt taactctttt    480

cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg ttgcctgtat    540

gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt gcatagcaat    600

caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa actgagaaat    660

aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga cttaaaatca    720

gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc tacagggaaa    780

taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat cttatagccg    840

ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta taacttagcc    900

aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt cttttgataa    960

actgcagtat tctttaagtg tactttgtcc ttttgtttat tgctacaatt taagaacttt   1020

atttaaaaac aattttggaa ggttactagg tacagctttt gcagaagaaa ctgaactgta   1080

gccagatggt cagcaagtaa actacatgac ttagagttct tgtgcattat acattttggg   1140

taattcaaag tactgtattt gcattgacta taaagcgtcg tttgcaatat ttattcttcc   1200


<210>  5667
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5667

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5668
<211>  1377
<212>  DNA
<213>  Homo sapiens

<400>  5668
gggagaagag ggcggcggga cctttcctgg cgccgctcgc agtttacatg tggatttatt     60

cattctggag atacaatggc aaggaaacag ctgtgagtct tgctgtgtgg cccaggctgg    120

agtgcccggc tggtctcaaa ttcctgacct caagtgatct ccctcccaaa gtgttgcgat    180

tgcaggtgtg agccactgca cctggctgct gagaaatctt tgcctacagt gagggaaact    240

actaaagttc ctggggaagc aaagtagaat ttcataagaa caaaatggat ggagaggaga    300

aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt caaattgata tcatctgatg    360

gccatgaatt tattgtaaaa agagaacatg cattaacatc aggcacgata aaagccatgt    420

tgagtggccc aggtcagttt gctgagaacg aaaccaatga ggtcaatttt agagagatac    480

cttcacatgt gctatcgaaa gtatgcatgt attttacgta caaggttcgc tacactaaca    540

gctccaccga gattcctgaa ttcccaattg cacctgaaat tgcactggaa ctgctgatgg    600

ctgcgaactt cttagattgt taaataaaat aaattataat aaactgttaa ctcttttcag    660

tatttaatac ctgtagttca gttagtaact ttttcatata tagcatgttg cctgtatgca    720

gttgaactat ataaagttca ttgcaaagca gattatcttg tttttttgca tagcaatcaa    780

agttgaaatt tgtttgctac atcaacaaat taaggacatt ttcacaaact gagaaataaa    840

caaatatgcc aattcgtagg tggttttgcc ttatcctttg aatgtgactt aaaatcagca    900

atgatgatat agtaaatact gaaatttagg tgtaaatcaa tacgttctac agggaaataa    960

tgaggctaag tatttttatg tttttagtgg ttttttagaa acctaatctt atagccgcca   1020

ttagcattac tagagttatg caaataattg cattataaac atgtttataa cttagccaaa   1080

acattgattt ttataactct ccaagtatga gttgaaattt cttatgtctt ttgataaact   1140

gcagtattct ttaagtgtac tttgtccttt tgtttattgc tacaatttaa gaactttatt   1200

taaaaacaat tttggaaggt tactaggtac agcttttgca gaagaaactg aactgtagcc   1260

agatggtcag caagtaaact acatgactta gagttcttgt gcattataca ttttgggtaa   1320

ttcaaagtac tgtatttgca ttgactataa agcgtcgttt gcaatattta ttcttcc      1377


<210>  5669
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5669

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5670
<211>  1208
<212>  DNA
<213>  Homo sapiens

<400>  5670
acccggctgc ggtggctgcg ggactgacga gtgagtctcg ggctggggcg gaaacggagc     60

tccgggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga acaaaatgga    120

tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg tcaaattgat    180

atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat caggcacgat    240

aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg aggtcaattt    300

tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt acaaggttcg    360

ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa ttgcactgga    420

actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa taaactgtta    480

actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat atagcatgtt    540

gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt gtttttttgc    600

atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat tttcacaaac    660

tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt gaatgtgact    720

taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca atacgttcta    780

cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga aacctaatct    840

tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa catgtttata    900

acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt tcttatgtct    960

tttgataaac tgcagtattc tttaagtgta ctttgtcctt ttgtttattg ctacaattta   1020

agaactttat ttaaaaacaa ttttggaagg ttactaggta cagcttttgc agaagaaact   1080

gaactgtagc cagatggtca gcaagtaaac tacatgactt agagttcttg tgcattatac   1140

attttgggta attcaaagta ctgtatttgc attgactata aagcgtcgtt tgcaatattt   1200

attcttcc                                                            1208


<210>  5671
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5671

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5672
<211>  1413
<212>  DNA
<213>  Homo sapiens

<400>  5672
cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat tctttcgact gccccggaac     60

ccaccggagc aggcagctgg gggtgggggg gcggccctgg gataggggct gtggcagtac    120

gcggggaccc ggctgcggtg gctgcgggac tgacgagatc atcagggaag gaagacctct    180

ctgaggagtt gatgttttac ctggagacct aaatgatgag gatttaaaag cttttcggac    240

aacagcaatt acaaatgcaa agaccttgag gaaactacta aagttcctgg ggaagcaaag    300

tagaatttca taagaacaaa atggatggag aggagaaaac ctatggtggc tgtgaaggac    360

ctgatgccat gtatgtcaaa ttgatatcat ctgatggcca tgaatttatt gtaaaaagag    420

aacatgcatt aacatcaggc acgataaaag ccatgttgag tggcccaggt cagtttgctg    480

agaacgaaac caatgaggtc aattttagag agataccttc acatgtgcta tcgaaagtat    540

gcatgtattt tacgtacaag gttcgctaca ctaacagctc caccgagatt cctgaattcc    600

caattgcacc tgaaattgca ctggaactgc tgatggctgc gaacttctta gattgttaaa    660

taaaataaat tataataaac tgttaactct tttcagtatt taatacctgt agttcagtta    720

gtaacttttt catatatagc atgttgcctg tatgcagttg aactatataa agttcattgc    780

aaagcagatt atcttgtttt tttgcatagc aatcaaagtt gaaatttgtt tgctacatca    840

acaaattaag gacattttca caaactgaga aataaacaaa tatgccaatt cgtaggtggt    900

tttgccttat cctttgaatg tgacttaaaa tcagcaatga tgatatagta aatactgaaa    960

tttaggtgta aatcaatacg ttctacaggg aaataatgag gctaagtatt tttatgtttt   1020

tagtggtttt ttagaaacct aatcttatag ccgccattag cattactaga gttatgcaaa   1080

taattgcatt ataaacatgt ttataactta gccaaaacat tgatttttat aactctccaa   1140

gtatgagttg aaatttctta tgtcttttga taaactgcag tattctttaa gtgtactttg   1200

tccttttgtt tattgctaca atttaagaac tttatttaaa aacaattttg gaaggttact   1260

aggtacagct tttgcagaag aaactgaact gtagccagat ggtcagcaag taaactacat   1320

gacttagagt tcttgtgcat tatacatttt gggtaattca aagtactgta tttgcattga   1380

ctataaagcg tcgtttgcaa tatttattct tcc                                1413


<210>  5673
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5673

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5674
<211>  1458
<212>  DNA
<213>  Homo sapiens

<400>  5674
ctcaccaggt acggatctcc cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat     60

tctttcgact gccccggaac ccaccggagc aggcagctgg gggtgggggg gcggccctgg    120

gataggggct gtggcagtac gcggggaccc ggctgcggtg gctgcgggac tgacgaagtc    180

ttgctgtgtg gcccaggctg gagtgcccgg ctggtctcaa attcctgacc tcaagtgatc    240

tccctcccaa agtgttgcga ttgcaggtgt gagccactgc acctggctgc tgagaaatct    300

ttgcctacag tgagggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga    360

acaaaatgga tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg    420

tcaaattgat atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat    480

caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg    540

aggtcaattt tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt    600

acaaggttcg ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa    660

ttgcactgga actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa    720

taaactgtta actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat    780

atagcatgtt gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt    840

gtttttttgc atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat    900

tttcacaaac tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt    960

gaatgtgact taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca   1020

atacgttcta cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga   1080

aacctaatct tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa   1140

catgtttata acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt   1200

tcttatgtct tttgataaac tgcagtattc tttaagtgta ctttgtcctt ttgtttattg   1260

ctacaattta agaactttat ttaaaaacaa ttttggaagg ttactaggta cagcttttgc   1320

agaagaaact gaactgtagc cagatggtca gcaagtaaac tacatgactt agagttcttg   1380

tgcattatac attttgggta attcaaagta ctgtatttgc attgactata aagcgtcgtt   1440

tgcaatattt attcttcc                                                 1458


<210>  5675
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5675

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5676
<211>  1270
<212>  DNA
<213>  Homo sapiens

<400>  5676
ctcgcctcac caggtacgga tctcccgcgc gtcgccgaaa gcggctctga cccagcggaa     60

gtaattcttt cgactgcccc ggaacccacc ggagcaggca gctgggggtg ggggggcggc    120

cctgggatag gggctgtggc agtacgcggg gacccggctg cggtggctgc gggactgacg    180

aatggagagg agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg    240

atatcatctg atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg    300

ataaaagcca tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat    360

tttagagaga taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt    420

cgctacacta acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg    480

gaactgctga tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt    540

taactctttt cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg    600

ttgcctgtat gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt    660

gcatagcaat caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa    720

actgagaaat aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga    780

cttaaaatca gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc    840

tacagggaaa taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat    900

cttatagccg ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta    960

taacttagcc aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt   1020

cttttgataa actgcagtat tctttaagtg tactttgtcc ttttgtttat tgctacaatt   1080

taagaacttt atttaaaaac aattttggaa ggttactagg tacagctttt gcagaagaaa   1140

ctgaactgta gccagatggt cagcaagtaa actacatgac ttagagttct tgtgcattat   1200

acattttggg taattcaaag tactgtattt gcattgacta taaagcgtcg tttgcaatat   1260

ttattcttcc                                                          1270


<210>  5677
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5677

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5678
<211>  1337
<212>  DNA
<213>  Homo sapiens

<400>  5678
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tatttaatac ctgtagttca gttagtaact ttttcatata    660

tagcatgttg cctgtatgca gttgaactat ataaagttca ttgcaaagca gattatcttg    720

tttttttgca tagcaatcaa agttgaaatt tgtttgctac atcaacaaat taaggacatt    780

ttcacaaact gagaaataaa caaatatgcc aattcgtagg tggttttgcc ttatcctttg    840

aatgtgactt aaaatcagca atgatgatat agtaaatact gaaatttagg tgtaaatcaa    900

tacgttctac agggaaataa tgaggctaag tatttttatg tttttagtgg ttttttagaa    960

acctaatctt atagccgcca ttagcattac tagagttatg caaataattg cattataaac   1020

atgtttataa cttagccaaa acattgattt ttataactct ccaagtatga gttgaaattt   1080

cttatgtctt ttgataaact gcagtattct ttaagtgtac tttgtccttt tgtttattgc   1140

tacaatttaa gaactttatt taaaaacaat tttggaaggt tactaggtac agcttttgca   1200

gaagaaactg aactgtagcc agatggtcag caagtaaact acatgactta gagttcttgt   1260

gcattataca ttttgggtaa ttcaaagtac tgtatttgca ttgactataa agcgtcgttt   1320

gcaatattta ttcttcc                                                  1337


<210>  5679
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5679

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5680
<211>  1324
<212>  DNA
<213>  Homo sapiens

<400>  5680
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agagtcttgc tgtgtggccc     60

aggctggagt gcccggctgg tctcaaattc ctgacctcaa gtgatctccc tcccaaagtg    120

ttgcgattgc aggtgtgagc cactgcacct ggctgctgag aaatctttgc ctacagtgag    180

ggaaactact aaagttcctg gggaagcaaa gtagaatttc ataagaacaa aatggatgga    240

gaggagaaaa cctatggtgg ctgtgaagga cctgatgcca tgtatgtcaa attgatatca    300

tctgatggcc atgaatttat tgtaaaaaga gaacatgcat taacatcagg cacgataaaa    360

gccatgttga gtggcccagg tcagtttgct gagaacgaaa ccaatgaggt caattttaga    420

gagatacctt cacatgtgct atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac    480

actaacagct ccaccgagat tcctgaattc ccaattgcac ctgaaattgc actggaactg    540

ctgatggctg cgaacttctt agattgttaa ataaaataaa ttataataaa ctgttaactc    600

ttttcagtat ttaatacctg tagttcagtt agtaactttt tcatatatag catgttgcct    660

gtatgcagtt gaactatata aagttcattg caaagcagat tatcttgttt ttttgcatag    720

caatcaaagt tgaaatttgt ttgctacatc aacaaattaa ggacattttc acaaactgag    780

aaataaacaa atatgccaat tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa    840

atcagcaatg atgatatagt aaatactgaa atttaggtgt aaatcaatac gttctacagg    900

gaaataatga ggctaagtat ttttatgttt ttagtggttt tttagaaacc taatcttata    960

gccgccatta gcattactag agttatgcaa ataattgcat tataaacatg tttataactt   1020

agccaaaaca ttgattttta taactctcca agtatgagtt gaaatttctt atgtcttttg   1080

ataaactgca gtattcttta agtgtacttt gtccttttgt ttattgctac aatttaagaa   1140

ctttatttaa aaacaatttt ggaaggttac taggtacagc ttttgcagaa gaaactgaac   1200

tgtagccaga tggtcagcaa gtaaactaca tgacttagag ttcttgtgca ttatacattt   1260

tgggtaattc aaagtactgt atttgcattg actataaagc gtcgtttgca atatttattc   1320

ttcc                                                                1324


<210>  5681
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5681

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5682
<211>  1185
<212>  DNA
<213>  Homo sapiens

<400>  5682
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc aggaaactac taaagttcct     60

ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa acctatggtg    120

gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc catgaattta    180

ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg agtggcccag    240

gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct tcacatgtgc    300

tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc tccaccgaga    360

ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct gcgaacttct    420

tagattgtta aataaaataa attataataa actgttaact cttttcagta tttaatacct    480

gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt tgaactatat    540

aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag ttgaaatttg    600

tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca aatatgccaa    660

ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat gatgatatag    720

taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg aggctaagta    780

tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt agcattacta    840

gagttatgca aataattgca ttataaacat gtttataact tagccaaaac attgattttt    900

ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc agtattcttt    960

aagtgtactt tgtccttttg tttattgcta caatttaaga actttattta aaaacaattt   1020

tggaaggtta ctaggtacag cttttgcaga agaaactgaa ctgtagccag atggtcagca   1080

agtaaactac atgacttaga gttcttgtgc attatacatt ttgggtaatt caaagtactg   1140

tatttgcatt gactataaag cgtcgtttgc aatatttatt cttcc                   1185


<210>  5683
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5683

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5684
<211>  1131
<212>  DNA
<213>  Homo sapiens

<400>  5684
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agatggagag gagaaaacct     60

atggtggctg tgaaggacct gatgccatgt atgtcaaatt gatatcatct gatggccatg    120

aatttattgt aaaaagagaa catgcattaa catcaggcac gataaaagcc atgttgagtg    180

gcccaggtca gtttgctgag aacgaaacca atgaggtcaa ttttagagag ataccttcac    240

atgtgctatc gaaagtatgc atgtatttta cgtacaaggt tcgctacact aacagctcca    300

ccgagattcc tgaattccca attgcacctg aaattgcact ggaactgctg atggctgcga    360

acttcttaga ttgttaaata aaataaatta taataaactg ttaactcttt tcagtattta    420

atacctgtag ttcagttagt aactttttca tatatagcat gttgcctgta tgcagttgaa    480

ctatataaag ttcattgcaa agcagattat cttgtttttt tgcatagcaa tcaaagttga    540

aatttgtttg ctacatcaac aaattaagga cattttcaca aactgagaaa taaacaaata    600

tgccaattcg taggtggttt tgccttatcc tttgaatgtg acttaaaatc agcaatgatg    660

atatagtaaa tactgaaatt taggtgtaaa tcaatacgtt ctacagggaa ataatgaggc    720

taagtatttt tatgttttta gtggtttttt agaaacctaa tcttatagcc gccattagca    780

ttactagagt tatgcaaata attgcattat aaacatgttt ataacttagc caaaacattg    840

atttttataa ctctccaagt atgagttgaa atttcttatg tcttttgata aactgcagta    900

ttctttaagt gtactttgtc cttttgttta ttgctacaat ttaagaactt tatttaaaaa    960

caattttgga aggttactag gtacagcttt tgcagaagaa actgaactgt agccagatgg   1020

tcagcaagta aactacatga cttagagttc ttgtgcatta tacattttgg gtaattcaaa   1080

gtactgtatt tgcattgact ataaagcgtc gtttgcaata tttattcttc c            1131


<210>  5685
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5685

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5686
<211>  839
<212>  DNA
<213>  Homo sapiens

<400>  5686
agagacagag tctcattctg ttgcccaggc tggagtgcaa tggtgcggtc tcagctcact     60

gcaatctccg cctgctgggt tcaggcaatt ctcctgcctc agagtagctg gaattacagg    120

tcagtttgct gagaacgaaa ccaatgaggt caattttaga gagatacctt cacatgtgct    180

atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac actaacagct ccaccgagat    240

tcctgaattc ccaattgcac ctgaaattgc actggaactg ctgatggctg cgaacttctt    300

agattgttaa ataaaataaa ttataataaa ctgttaactc ttttcagtat ttaatacctg    360

tagttcagtt agtaactttt tcatatatag catgttgcct gtatgcagtt gaactatata    420

aagttcattg caaagcagat tatcttgttt ttttgcatag caatcaaagt tgaaatttgt    480

ttgctacatc aacaaattaa ggacattttc acaaactgag aaataaacaa atatgccaat    540

tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa atcagcaatg atgatatagt    600

aaatactgaa atttaggtgt aaatcaatac gttctacagg gaaataatga ggctaagtat    660

ttttatgttt ttagtggttt tttagaaacc taatcttata gccgccatta gcattactag    720

agttatgcaa ataattgcat tataaacatg tttataactt agccaaaaca ttgattttta    780

taactctcca agtatgagtt gaaatttctt atgtcttttg ataaactgca gtattcttt     839


<210>  5687
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5687

Met Val Arg Ser Gln Leu Thr Ala Ile Ser Ala Cys Trp Val Gln Ala 
1               5                   10                  15


Ile Leu Leu Pro Gln Ser Ser Trp Asn Tyr Arg Ser Val Cys 
            20                  25                  30


<210>  5688
<211>  1030
<212>  DNA
<213>  Homo sapiens

<400>  5688
tgttagcatt tgcatagcta gaaaatttgg gttaatttta ttaccgatgt cactttcaaa     60

agcttaatta ggcagaaaac catcctagag tgatgatatc tttggagtta aggaaactac    120

taaagttcct ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa    180

acctatggtg gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc    240

catgaattta ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg    300

agtggcccag gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct    360

tcacatgtgc tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc    420

tccaccgaga ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct    480

gcgaacttct tagattgtta aataaaataa attataataa actgttaact cttttcagta    540

tttaatacct gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt    600

tgaactatat aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag    660

ttgaaatttg tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca    720

aatatgccaa ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat    780

gatgatatag taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg    840

aggctaagta tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt    900

agcattacta gagttatgca aataattgca ttataaacat gtttataact tagccaaaac    960

attgattttt ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc   1020

agtattcttt                                                          1030


<210>  5689
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5689

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5690
<211>  975
<212>  DNA
<213>  Homo sapiens

<400>  5690
gcagtttaca tgtggattta ttcattctgg agatacaatg gcaaggaaac agctgtggaa     60

actactaaag ttcctgggga agcaaagtag aatttcataa gaacaaaatg gatggagagg    120

agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg atatcatctg    180

atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg ataaaagcca    240

tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat tttagagaga    300

taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt cgctacacta    360

acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg gaactgctga    420

tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt taactctttt    480

cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg ttgcctgtat    540

gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt gcatagcaat    600

caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa actgagaaat    660

aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga cttaaaatca    720

gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc tacagggaaa    780

taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat cttatagccg    840

ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta taacttagcc    900

aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt cttttgataa    960

actgcagtat tcttt                                                     975


<210>  5691
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5691

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5692
<211>  1152
<212>  DNA
<213>  Homo sapiens

<400>  5692
gggagaagag ggcggcggga cctttcctgg cgccgctcgc agtttacatg tggatttatt     60

cattctggag atacaatggc aaggaaacag ctgtgagtct tgctgtgtgg cccaggctgg    120

agtgcccggc tggtctcaaa ttcctgacct caagtgatct ccctcccaaa gtgttgcgat    180

tgcaggtgtg agccactgca cctggctgct gagaaatctt tgcctacagt gagggaaact    240

actaaagttc ctggggaagc aaagtagaat ttcataagaa caaaatggat ggagaggaga    300

aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt caaattgata tcatctgatg    360

gccatgaatt tattgtaaaa agagaacatg cattaacatc aggcacgata aaagccatgt    420

tgagtggccc aggtcagttt gctgagaacg aaaccaatga ggtcaatttt agagagatac    480

cttcacatgt gctatcgaaa gtatgcatgt attttacgta caaggttcgc tacactaaca    540

gctccaccga gattcctgaa ttcccaattg cacctgaaat tgcactggaa ctgctgatgg    600

ctgcgaactt cttagattgt taaataaaat aaattataat aaactgttaa ctcttttcag    660

tatttaatac ctgtagttca gttagtaact ttttcatata tagcatgttg cctgtatgca    720

gttgaactat ataaagttca ttgcaaagca gattatcttg tttttttgca tagcaatcaa    780

agttgaaatt tgtttgctac atcaacaaat taaggacatt ttcacaaact gagaaataaa    840

caaatatgcc aattcgtagg tggttttgcc ttatcctttg aatgtgactt aaaatcagca    900

atgatgatat agtaaatact gaaatttagg tgtaaatcaa tacgttctac agggaaataa    960

tgaggctaag tatttttatg tttttagtgg ttttttagaa acctaatctt atagccgcca   1020

ttagcattac tagagttatg caaataattg cattataaac atgtttataa cttagccaaa   1080

acattgattt ttataactct ccaagtatga gttgaaattt cttatgtctt ttgataaact   1140

gcagtattct tt                                                       1152


<210>  5693
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5693

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5694
<211>  983
<212>  DNA
<213>  Homo sapiens

<400>  5694
acccggctgc ggtggctgcg ggactgacga gtgagtctcg ggctggggcg gaaacggagc     60

tccgggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga acaaaatgga    120

tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg tcaaattgat    180

atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat caggcacgat    240

aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg aggtcaattt    300

tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt acaaggttcg    360

ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa ttgcactgga    420

actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa taaactgtta    480

actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat atagcatgtt    540

gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt gtttttttgc    600

atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat tttcacaaac    660

tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt gaatgtgact    720

taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca atacgttcta    780

cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga aacctaatct    840

tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa catgtttata    900

acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt tcttatgtct    960

tttgataaac tgcagtattc ttt                                            983


<210>  5695
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5695

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5696
<211>  1188
<212>  DNA
<213>  Homo sapiens

<400>  5696
cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat tctttcgact gccccggaac     60

ccaccggagc aggcagctgg gggtgggggg gcggccctgg gataggggct gtggcagtac    120

gcggggaccc ggctgcggtg gctgcgggac tgacgagatc atcagggaag gaagacctct    180

ctgaggagtt gatgttttac ctggagacct aaatgatgag gatttaaaag cttttcggac    240

aacagcaatt acaaatgcaa agaccttgag gaaactacta aagttcctgg ggaagcaaag    300

tagaatttca taagaacaaa atggatggag aggagaaaac ctatggtggc tgtgaaggac    360

ctgatgccat gtatgtcaaa ttgatatcat ctgatggcca tgaatttatt gtaaaaagag    420

aacatgcatt aacatcaggc acgataaaag ccatgttgag tggcccaggt cagtttgctg    480

agaacgaaac caatgaggtc aattttagag agataccttc acatgtgcta tcgaaagtat    540

gcatgtattt tacgtacaag gttcgctaca ctaacagctc caccgagatt cctgaattcc    600

caattgcacc tgaaattgca ctggaactgc tgatggctgc gaacttctta gattgttaaa    660

taaaataaat tataataaac tgttaactct tttcagtatt taatacctgt agttcagtta    720

gtaacttttt catatatagc atgttgcctg tatgcagttg aactatataa agttcattgc    780

aaagcagatt atcttgtttt tttgcatagc aatcaaagtt gaaatttgtt tgctacatca    840

acaaattaag gacattttca caaactgaga aataaacaaa tatgccaatt cgtaggtggt    900

tttgccttat cctttgaatg tgacttaaaa tcagcaatga tgatatagta aatactgaaa    960

tttaggtgta aatcaatacg ttctacaggg aaataatgag gctaagtatt tttatgtttt   1020

tagtggtttt ttagaaacct aatcttatag ccgccattag cattactaga gttatgcaaa   1080

taattgcatt ataaacatgt ttataactta gccaaaacat tgatttttat aactctccaa   1140

gtatgagttg aaatttctta tgtcttttga taaactgcag tattcttt                1188


<210>  5697
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5697

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5698
<211>  1233
<212>  DNA
<213>  Homo sapiens

<400>  5698
ctcaccaggt acggatctcc cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat     60

tctttcgact gccccggaac ccaccggagc aggcagctgg gggtgggggg gcggccctgg    120

gataggggct gtggcagtac gcggggaccc ggctgcggtg gctgcgggac tgacgaagtc    180

ttgctgtgtg gcccaggctg gagtgcccgg ctggtctcaa attcctgacc tcaagtgatc    240

tccctcccaa agtgttgcga ttgcaggtgt gagccactgc acctggctgc tgagaaatct    300

ttgcctacag tgagggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga    360

acaaaatgga tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg    420

tcaaattgat atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat    480

caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg    540

aggtcaattt tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt    600

acaaggttcg ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa    660

ttgcactgga actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa    720

taaactgtta actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat    780

atagcatgtt gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt    840

gtttttttgc atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat    900

tttcacaaac tgagaaataa acaaatatgc caattcgtag gtggttttgc cttatccttt    960

gaatgtgact taaaatcagc aatgatgata tagtaaatac tgaaatttag gtgtaaatca   1020

atacgttcta cagggaaata atgaggctaa gtatttttat gtttttagtg gttttttaga   1080

aacctaatct tatagccgcc attagcatta ctagagttat gcaaataatt gcattataaa   1140

catgtttata acttagccaa aacattgatt tttataactc tccaagtatg agttgaaatt   1200

tcttatgtct tttgataaac tgcagtattc ttt                                1233


<210>  5699
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5699

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5700
<211>  1045
<212>  DNA
<213>  Homo sapiens

<400>  5700
ctcgcctcac caggtacgga tctcccgcgc gtcgccgaaa gcggctctga cccagcggaa     60

gtaattcttt cgactgcccc ggaacccacc ggagcaggca gctgggggtg ggggggcggc    120

cctgggatag gggctgtggc agtacgcggg gacccggctg cggtggctgc gggactgacg    180

aatggagagg agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg    240

atatcatctg atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg    300

ataaaagcca tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat    360

tttagagaga taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt    420

cgctacacta acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg    480

gaactgctga tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt    540

taactctttt cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg    600

ttgcctgtat gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt    660

gcatagcaat caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa    720

actgagaaat aaacaaatat gccaattcgt aggtggtttt gccttatcct ttgaatgtga    780

cttaaaatca gcaatgatga tatagtaaat actgaaattt aggtgtaaat caatacgttc    840

tacagggaaa taatgaggct aagtattttt atgtttttag tggtttttta gaaacctaat    900

cttatagccg ccattagcat tactagagtt atgcaaataa ttgcattata aacatgttta    960

taacttagcc aaaacattga tttttataac tctccaagta tgagttgaaa tttcttatgt   1020

cttttgataa actgcagtat tcttt                                         1045


<210>  5701
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5701

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5702
<211>  1112
<212>  DNA
<213>  Homo sapiens

<400>  5702
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tatttaatac ctgtagttca gttagtaact ttttcatata    660

tagcatgttg cctgtatgca gttgaactat ataaagttca ttgcaaagca gattatcttg    720

tttttttgca tagcaatcaa agttgaaatt tgtttgctac atcaacaaat taaggacatt    780

ttcacaaact gagaaataaa caaatatgcc aattcgtagg tggttttgcc ttatcctttg    840

aatgtgactt aaaatcagca atgatgatat agtaaatact gaaatttagg tgtaaatcaa    900

tacgttctac agggaaataa tgaggctaag tatttttatg tttttagtgg ttttttagaa    960

acctaatctt atagccgcca ttagcattac tagagttatg caaataattg cattataaac   1020

atgtttataa cttagccaaa acattgattt ttataactct ccaagtatga gttgaaattt   1080

cttatgtctt ttgataaact gcagtattct tt                                 1112


<210>  5703
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5703

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5704
<211>  960
<212>  DNA
<213>  Homo sapiens

<400>  5704
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc aggaaactac taaagttcct     60

ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa acctatggtg    120

gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc catgaattta    180

ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg agtggcccag    240

gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct tcacatgtgc    300

tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc tccaccgaga    360

ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct gcgaacttct    420

tagattgtta aataaaataa attataataa actgttaact cttttcagta tttaatacct    480

gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt tgaactatat    540

aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag ttgaaatttg    600

tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca aatatgccaa    660

ttcgtaggtg gttttgcctt atcctttgaa tgtgacttaa aatcagcaat gatgatatag    720

taaatactga aatttaggtg taaatcaata cgttctacag ggaaataatg aggctaagta    780

tttttatgtt tttagtggtt ttttagaaac ctaatcttat agccgccatt agcattacta    840

gagttatgca aataattgca ttataaacat gtttataact tagccaaaac attgattttt    900

ataactctcc aagtatgagt tgaaatttct tatgtctttt gataaactgc agtattcttt    960


<210>  5705
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5705

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5706
<211>  906
<212>  DNA
<213>  Homo sapiens

<400>  5706
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agatggagag gagaaaacct     60

atggtggctg tgaaggacct gatgccatgt atgtcaaatt gatatcatct gatggccatg    120

aatttattgt aaaaagagaa catgcattaa catcaggcac gataaaagcc atgttgagtg    180

gcccaggtca gtttgctgag aacgaaacca atgaggtcaa ttttagagag ataccttcac    240

atgtgctatc gaaagtatgc atgtatttta cgtacaaggt tcgctacact aacagctcca    300

ccgagattcc tgaattccca attgcacctg aaattgcact ggaactgctg atggctgcga    360

acttcttaga ttgttaaata aaataaatta taataaactg ttaactcttt tcagtattta    420

atacctgtag ttcagttagt aactttttca tatatagcat gttgcctgta tgcagttgaa    480

ctatataaag ttcattgcaa agcagattat cttgtttttt tgcatagcaa tcaaagttga    540

aatttgtttg ctacatcaac aaattaagga cattttcaca aactgagaaa taaacaaata    600

tgccaattcg taggtggttt tgccttatcc tttgaatgtg acttaaaatc agcaatgatg    660

atatagtaaa tactgaaatt taggtgtaaa tcaatacgtt ctacagggaa ataatgaggc    720

taagtatttt tatgttttta gtggtttttt agaaacctaa tcttatagcc gccattagca    780

ttactagagt tatgcaaata attgcattat aaacatgttt ataacttagc caaaacattg    840

atttttataa ctctccaagt atgagttgaa atttcttatg tcttttgata aactgcagta    900

ttcttt                                                               906


<210>  5707
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5707

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5708
<211>  1099
<212>  DNA
<213>  Homo sapiens

<400>  5708
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agagtcttgc tgtgtggccc     60

aggctggagt gcccggctgg tctcaaattc ctgacctcaa gtgatctccc tcccaaagtg    120

ttgcgattgc aggtgtgagc cactgcacct ggctgctgag aaatctttgc ctacagtgag    180

ggaaactact aaagttcctg gggaagcaaa gtagaatttc ataagaacaa aatggatgga    240

gaggagaaaa cctatggtgg ctgtgaagga cctgatgcca tgtatgtcaa attgatatca    300

tctgatggcc atgaatttat tgtaaaaaga gaacatgcat taacatcagg cacgataaaa    360

gccatgttga gtggcccagg tcagtttgct gagaacgaaa ccaatgaggt caattttaga    420

gagatacctt cacatgtgct atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac    480

actaacagct ccaccgagat tcctgaattc ccaattgcac ctgaaattgc actggaactg    540

ctgatggctg cgaacttctt agattgttaa ataaaataaa ttataataaa ctgttaactc    600

ttttcagtat ttaatacctg tagttcagtt agtaactttt tcatatatag catgttgcct    660

gtatgcagtt gaactatata aagttcattg caaagcagat tatcttgttt ttttgcatag    720

caatcaaagt tgaaatttgt ttgctacatc aacaaattaa ggacattttc acaaactgag    780

aaataaacaa atatgccaat tcgtaggtgg ttttgcctta tcctttgaat gtgacttaaa    840

atcagcaatg atgatatagt aaatactgaa atttaggtgt aaatcaatac gttctacagg    900

gaaataatga ggctaagtat ttttatgttt ttagtggttt tttagaaacc taatcttata    960

gccgccatta gcattactag agttatgcaa ataattgcat tataaacatg tttataactt   1020

agccaaaaca ttgattttta taactctcca agtatgagtt gaaatttctt atgtcttttg   1080

ataaactgca gtattcttt                                                1099


<210>  5709
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5709

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5710
<211>  544
<212>  DNA
<213>  Homo sapiens

<400>  5710
agagacagag tctcattctg ttgcccaggc tggagtgcaa tggtgcggtc tcagctcact     60

gcaatctccg cctgctgggt tcaggcaatt ctcctgcctc agagtagctg gaattacagg    120

tcagtttgct gagaacgaaa ccaatgaggt caattttaga gagatacctt cacatgtgct    180

atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac actaacagct ccaccgagat    240

tcctgaattc ccaattgcac ctgaaattgc actggaactg ctgatggctg cgaacttctt    300

agattgttaa ataaaataaa ttataataaa ctgttaactc ttttcagtat ttaatacctg    360

tagttcagtt agtaactttt tcatatatag catgttgcct gtatgcagtt gaactatata    420

aagttcattg caaagcagat tatcttgttt ttttgcatag caatcaaagt tgaaatttgt    480

ttgctacatc aacaaattaa ggacattttc acaaactgag aaataaacaa atatgccaat    540

tcgt                                                                 544


<210>  5711
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5711

Met Val Arg Ser Gln Leu Thr Ala Ile Ser Ala Cys Trp Val Gln Ala 
1               5                   10                  15


Ile Leu Leu Pro Gln Ser Ser Trp Asn Tyr Arg Ser Val Cys 
            20                  25                  30


<210>  5712
<211>  735
<212>  DNA
<213>  Homo sapiens

<400>  5712
tgttagcatt tgcatagcta gaaaatttgg gttaatttta ttaccgatgt cactttcaaa     60

agcttaatta ggcagaaaac catcctagag tgatgatatc tttggagtta aggaaactac    120

taaagttcct ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa    180

acctatggtg gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc    240

catgaattta ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg    300

agtggcccag gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct    360

tcacatgtgc tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc    420

tccaccgaga ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct    480

gcgaacttct tagattgtta aataaaataa attataataa actgttaact cttttcagta    540

tttaatacct gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt    600

tgaactatat aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag    660

ttgaaatttg tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca    720

aatatgccaa ttcgt                                                     735


<210>  5713
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5713

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5714
<211>  857
<212>  DNA
<213>  Homo sapiens

<400>  5714
gggagaagag ggcggcggga cctttcctgg cgccgctcgc agtttacatg tggatttatt     60

cattctggag atacaatggc aaggaaacag ctgtgagtct tgctgtgtgg cccaggctgg    120

agtgcccggc tggtctcaaa ttcctgacct caagtgatct ccctcccaaa gtgttgcgat    180

tgcaggtgtg agccactgca cctggctgct gagaaatctt tgcctacagt gagggaaact    240

actaaagttc ctggggaagc aaagtagaat ttcataagaa caaaatggat ggagaggaga    300

aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt caaattgata tcatctgatg    360

gccatgaatt tattgtaaaa agagaacatg cattaacatc aggcacgata aaagccatgt    420

tgagtggccc aggtcagttt gctgagaacg aaaccaatga ggtcaatttt agagagatac    480

cttcacatgt gctatcgaaa gtatgcatgt attttacgta caaggttcgc tacactaaca    540

gctccaccga gattcctgaa ttcccaattg cacctgaaat tgcactggaa ctgctgatgg    600

ctgcgaactt cttagattgt taaataaaat aaattataat aaactgttaa ctcttttcag    660

tatttaatac ctgtagttca gttagtaact ttttcatata tagcatgttg cctgtatgca    720

gttgaactat ataaagttca ttgcaaagca gattatcttg tttttttgca tagcaatcaa    780

agttgaaatt tgtttgctac atcaacaaat taaggacatt ttcacaaact gagaaataaa    840

caaatatgcc aattcgt                                                   857


<210>  5715
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5715

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5716
<211>  688
<212>  DNA
<213>  Homo sapiens

<400>  5716
acccggctgc ggtggctgcg ggactgacga gtgagtctcg ggctggggcg gaaacggagc     60

tccgggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga acaaaatgga    120

tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg tcaaattgat    180

atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat caggcacgat    240

aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg aggtcaattt    300

tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt acaaggttcg    360

ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa ttgcactgga    420

actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa taaactgtta    480

actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat atagcatgtt    540

gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt gtttttttgc    600

atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat tttcacaaac    660

tgagaaataa acaaatatgc caattcgt                                       688


<210>  5717
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5717

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5718
<211>  893
<212>  DNA
<213>  Homo sapiens

<400>  5718
cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat tctttcgact gccccggaac     60

ccaccggagc aggcagctgg gggtgggggg gcggccctgg gataggggct gtggcagtac    120

gcggggaccc ggctgcggtg gctgcgggac tgacgagatc atcagggaag gaagacctct    180

ctgaggagtt gatgttttac ctggagacct aaatgatgag gatttaaaag cttttcggac    240

aacagcaatt acaaatgcaa agaccttgag gaaactacta aagttcctgg ggaagcaaag    300

tagaatttca taagaacaaa atggatggag aggagaaaac ctatggtggc tgtgaaggac    360

ctgatgccat gtatgtcaaa ttgatatcat ctgatggcca tgaatttatt gtaaaaagag    420

aacatgcatt aacatcaggc acgataaaag ccatgttgag tggcccaggt cagtttgctg    480

agaacgaaac caatgaggtc aattttagag agataccttc acatgtgcta tcgaaagtat    540

gcatgtattt tacgtacaag gttcgctaca ctaacagctc caccgagatt cctgaattcc    600

caattgcacc tgaaattgca ctggaactgc tgatggctgc gaacttctta gattgttaaa    660

taaaataaat tataataaac tgttaactct tttcagtatt taatacctgt agttcagtta    720

gtaacttttt catatatagc atgttgcctg tatgcagttg aactatataa agttcattgc    780

aaagcagatt atcttgtttt tttgcatagc aatcaaagtt gaaatttgtt tgctacatca    840

acaaattaag gacattttca caaactgaga aataaacaaa tatgccaatt cgt           893


<210>  5719
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5719

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5720
<211>  938
<212>  DNA
<213>  Homo sapiens

<400>  5720
ctcaccaggt acggatctcc cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat     60

tctttcgact gccccggaac ccaccggagc aggcagctgg gggtgggggg gcggccctgg    120

gataggggct gtggcagtac gcggggaccc ggctgcggtg gctgcgggac tgacgaagtc    180

ttgctgtgtg gcccaggctg gagtgcccgg ctggtctcaa attcctgacc tcaagtgatc    240

tccctcccaa agtgttgcga ttgcaggtgt gagccactgc acctggctgc tgagaaatct    300

ttgcctacag tgagggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga    360

acaaaatgga tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg    420

tcaaattgat atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat    480

caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg    540

aggtcaattt tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt    600

acaaggttcg ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa    660

ttgcactgga actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa    720

taaactgtta actcttttca gtatttaata cctgtagttc agttagtaac tttttcatat    780

atagcatgtt gcctgtatgc agttgaacta tataaagttc attgcaaagc agattatctt    840

gtttttttgc atagcaatca aagttgaaat ttgtttgcta catcaacaaa ttaaggacat    900

tttcacaaac tgagaaataa acaaatatgc caattcgt                            938


<210>  5721
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5721

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5722
<211>  750
<212>  DNA
<213>  Homo sapiens

<400>  5722
ctcgcctcac caggtacgga tctcccgcgc gtcgccgaaa gcggctctga cccagcggaa     60

gtaattcttt cgactgcccc ggaacccacc ggagcaggca gctgggggtg ggggggcggc    120

cctgggatag gggctgtggc agtacgcggg gacccggctg cggtggctgc gggactgacg    180

aatggagagg agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg    240

atatcatctg atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg    300

ataaaagcca tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat    360

tttagagaga taccttcaca tgtgctatcg aaagtatgca tgtattttac gtacaaggtt    420

cgctacacta acagctccac cgagattcct gaattcccaa ttgcacctga aattgcactg    480

gaactgctga tggctgcgaa cttcttagat tgttaaataa aataaattat aataaactgt    540

taactctttt cagtatttaa tacctgtagt tcagttagta actttttcat atatagcatg    600

ttgcctgtat gcagttgaac tatataaagt tcattgcaaa gcagattatc ttgttttttt    660

gcatagcaat caaagttgaa atttgtttgc tacatcaaca aattaaggac attttcacaa    720

actgagaaat aaacaaatat gccaattcgt                                     750


<210>  5723
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5723

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5724
<211>  817
<212>  DNA
<213>  Homo sapiens

<400>  5724
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tatttaatac ctgtagttca gttagtaact ttttcatata    660

tagcatgttg cctgtatgca gttgaactat ataaagttca ttgcaaagca gattatcttg    720

tttttttgca tagcaatcaa agttgaaatt tgtttgctac atcaacaaat taaggacatt    780

ttcacaaact gagaaataaa caaatatgcc aattcgt                             817


<210>  5725
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5725

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5726
<211>  665
<212>  DNA
<213>  Homo sapiens

<400>  5726
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc aggaaactac taaagttcct     60

ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa acctatggtg    120

gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc catgaattta    180

ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg agtggcccag    240

gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct tcacatgtgc    300

tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc tccaccgaga    360

ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct gcgaacttct    420

tagattgtta aataaaataa attataataa actgttaact cttttcagta tttaatacct    480

gtagttcagt tagtaacttt ttcatatata gcatgttgcc tgtatgcagt tgaactatat    540

aaagttcatt gcaaagcaga ttatcttgtt tttttgcata gcaatcaaag ttgaaatttg    600

tttgctacat caacaaatta aggacatttt cacaaactga gaaataaaca aatatgccaa    660

ttcgt                                                                665


<210>  5727
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5727

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5728
<211>  611
<212>  DNA
<213>  Homo sapiens

<400>  5728
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agatggagag gagaaaacct     60

atggtggctg tgaaggacct gatgccatgt atgtcaaatt gatatcatct gatggccatg    120

aatttattgt aaaaagagaa catgcattaa catcaggcac gataaaagcc atgttgagtg    180

gcccaggtca gtttgctgag aacgaaacca atgaggtcaa ttttagagag ataccttcac    240

atgtgctatc gaaagtatgc atgtatttta cgtacaaggt tcgctacact aacagctcca    300

ccgagattcc tgaattccca attgcacctg aaattgcact ggaactgctg atggctgcga    360

acttcttaga ttgttaaata aaataaatta taataaactg ttaactcttt tcagtattta    420

atacctgtag ttcagttagt aactttttca tatatagcat gttgcctgta tgcagttgaa    480

ctatataaag ttcattgcaa agcagattat cttgtttttt tgcatagcaa tcaaagttga    540

aatttgtttg ctacatcaac aaattaagga cattttcaca aactgagaaa taaacaaata    600

tgccaattcg t                                                         611


<210>  5729
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5729

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5730
<211>  804
<212>  DNA
<213>  Homo sapiens

<400>  5730
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agagtcttgc tgtgtggccc     60

aggctggagt gcccggctgg tctcaaattc ctgacctcaa gtgatctccc tcccaaagtg    120

ttgcgattgc aggtgtgagc cactgcacct ggctgctgag aaatctttgc ctacagtgag    180

ggaaactact aaagttcctg gggaagcaaa gtagaatttc ataagaacaa aatggatgga    240

gaggagaaaa cctatggtgg ctgtgaagga cctgatgcca tgtatgtcaa attgatatca    300

tctgatggcc atgaatttat tgtaaaaaga gaacatgcat taacatcagg cacgataaaa    360

gccatgttga gtggcccagg tcagtttgct gagaacgaaa ccaatgaggt caattttaga    420

gagatacctt cacatgtgct atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac    480

actaacagct ccaccgagat tcctgaattc ccaattgcac ctgaaattgc actggaactg    540

ctgatggctg cgaacttctt agattgttaa ataaaataaa ttataataaa ctgttaactc    600

ttttcagtat ttaatacctg tagttcagtt agtaactttt tcatatatag catgttgcct    660

gtatgcagtt gaactatata aagttcattg caaagcagat tatcttgttt ttttgcatag    720

caatcaaagt tgaaatttgt ttgctacatc aacaaattaa ggacattttc acaaactgag    780

aaataaacaa atatgccaat tcgt                                           804


<210>  5731
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5731

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5732
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  5732
tgttagcatt tgcatagcta gaaaatttgg gttaatttta ttaccgatgt cactttcaaa     60

agcttaatta ggcagaaaac catcctagag tgatgatatc tttggagtta aggaaactac    120

taaagttcct ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa    180

acctatggtg gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc    240

catgaattta ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg    300

agtggcccag gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct    360

tcacatgtgc tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc    420

tccaccgaga ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct    480

gcgaacttct tagattgtta aataaaataa attataataa actgttaact cttttcagta    540

ttt                                                                  543


<210>  5733
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5733

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5734
<211>  598
<212>  DNA
<213>  Homo sapiens

<400>  5734
aggggctgtg gcagtacgcg gggacccggc tgcggtggct gcgggactga cgagatcatc     60

agggaaggaa gacctctctg aggagttgat gttttacctg gagacctaaa tgatgaggat    120

ttaaaagctt ttcggacaac agcaattaca aatgcaaaga ccttgaggaa actactaaag    180

ttcctgggga agcaaagtag aatttcataa gaacaaaatg gatggagagg agaaaaccta    240

tggtggctgt gaaggacctg atgccatgta tgtcaaattg atatcatctg atggccatga    300

atttattgta aaaagagaac atgcattaac atcaggcacg ataaaagcca tgttgagtgg    360

cccaggtcag tttgctgaga acgaaaccaa tgaggtcaat tttagagaga taccttcaca    420

tgtgctatcg aaagtatgca tgtattttac gtacaaggtt cgctacacta acagctccac    480

cgagattcct gaattcccaa ttgcacctga aattgcactg gaactgctga tggctgcgaa    540

cttcttagat tgttaaataa aataaattat aataaactgt taactctttt cagtattt      598


<210>  5735
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5735

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5736
<211>  448
<212>  DNA
<213>  Homo sapiens

<400>  5736
ggggggcggc cctgggatag gggctgtggc agtacgcggg gacccggctg cggtggctgc     60

gggactgacg aatggagagg agaaaaccta tggtggctgt gaaggacctg atgccatgta    120

tgtcaaattg atatcatctg atggccatga atttattgta aaaagagaac atgcattaac    180

atcaggcacg ataaaagcca tgttgagtgg cccaggtcag tttgctgaga acgaaaccaa    240

tgaggtcaat tttagagaga taccttcaca tgtgctatcg aaagtatgca tgtattttac    300

gtacaaggtt cgctacacta acagctccac cgagattcct gaattcccaa ttgcacctga    360

aattgcactg gaactgctga tggctgcgaa cttcttagat tgttaaataa aataaattat    420

aataaactgt taactctttt cagtattt                                       448


<210>  5737
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5737

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5738
<211>  746
<212>  DNA
<213>  Homo sapiens

<400>  5738
ctcaccaggt acggatctcc cgcgcgtcgc cgaaagcggc tctgacccag cggaagtaat     60

tctttcgact gccccggaac ccaccggagc aggcagctgg gggtgggggg gcggccctgg    120

gataggggct gtggcagtac gcggggaccc ggctgcggtg gctgcgggac tgacgaagtc    180

ttgctgtgtg gcccaggctg gagtgcccgg ctggtctcaa attcctgacc tcaagtgatc    240

tccctcccaa agtgttgcga ttgcaggtgt gagccactgc acctggctgc tgagaaatct    300

ttgcctacag tgagggaaac tactaaagtt cctggggaag caaagtagaa tttcataaga    360

acaaaatgga tggagaggag aaaacctatg gtggctgtga aggacctgat gccatgtatg    420

tcaaattgat atcatctgat ggccatgaat ttattgtaaa aagagaacat gcattaacat    480

caggcacgat aaaagccatg ttgagtggcc caggtcagtt tgctgagaac gaaaccaatg    540

aggtcaattt tagagagata ccttcacatg tgctatcgaa agtatgcatg tattttacgt    600

acaaggttcg ctacactaac agctccaccg agattcctga attcccaatt gcacctgaaa    660

ttgcactgga actgctgatg gctgcgaact tcttagattg ttaaataaaa taaattataa    720

taaactgtta actcttttca gtattt                                         746


<210>  5739
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5739

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5740
<211>  625
<212>  DNA
<213>  Homo sapiens

<400>  5740
cacactctgc gtcctcgcct caccaggtac ggatctcccg cgcgtcgccg aaagcggctc     60

tgacccagcg gaagtaattc tttcgactgc cccggaaccc accggagcag gcagctgggg    120

gtgggggggc ggccctggga taggggctgt ggcagtacgc ggggacccgg ctgcggtggc    180

tgcgggactg acgagaaact actaaagttc ctggggaagc aaagtagaat ttcataagaa    240

caaaatggat ggagaggaga aaacctatgg tggctgtgaa ggacctgatg ccatgtatgt    300

caaattgata tcatctgatg gccatgaatt tattgtaaaa agagaacatg cattaacatc    360

aggcacgata aaagccatgt tgagtggccc aggtcagttt gctgagaacg aaaccaatga    420

ggtcaatttt agagagatac cttcacatgt gctatcgaaa gtatgcatgt attttacgta    480

caaggttcgc tacactaaca gctccaccga gattcctgaa ttcccaattg cacctgaaat    540

tgcactggaa ctgctgatgg ctgcgaactt cttagattgt taaataaaat aaattataat    600

aaactgttaa ctcttttcag tattt                                          625


<210>  5741
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5741

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5742
<211>  473
<212>  DNA
<213>  Homo sapiens

<400>  5742
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc aggaaactac taaagttcct     60

ggggaagcaa agtagaattt cataagaaca aaatggatgg agaggagaaa acctatggtg    120

gctgtgaagg acctgatgcc atgtatgtca aattgatatc atctgatggc catgaattta    180

ttgtaaaaag agaacatgca ttaacatcag gcacgataaa agccatgttg agtggcccag    240

gtcagtttgc tgagaacgaa accaatgagg tcaattttag agagatacct tcacatgtgc    300

tatcgaaagt atgcatgtat tttacgtaca aggttcgcta cactaacagc tccaccgaga    360

ttcctgaatt cccaattgca cctgaaattg cactggaact gctgatggct gcgaacttct    420

tagattgtta aataaaataa attataataa actgttaact cttttcagta ttt           473


<210>  5743
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5743

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5744
<211>  419
<212>  DNA
<213>  Homo sapiens

<400>  5744
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agatggagag gagaaaacct     60

atggtggctg tgaaggacct gatgccatgt atgtcaaatt gatatcatct gatggccatg    120

aatttattgt aaaaagagaa catgcattaa catcaggcac gataaaagcc atgttgagtg    180

gcccaggtca gtttgctgag aacgaaacca atgaggtcaa ttttagagag ataccttcac    240

atgtgctatc gaaagtatgc atgtatttta cgtacaaggt tcgctacact aacagctcca    300

ccgagattcc tgaattccca attgcacctg aaattgcact ggaactgctg atggctgcga    360

acttcttaga ttgttaaata aaataaatta taataaactg ttaactcttt tcagtattt     419


<210>  5745
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5745

Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
1               5                   10                  15


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
            20                  25                  30


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
        35                  40                  45


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
    50                  55                  60


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
65                  70                  75                  80


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
                85                  90                  95


<210>  5746
<211>  612
<212>  DNA
<213>  Homo sapiens

<400>  5746
agacggaagt gagcgacaca ctctgcgtcc tcgcctcacc agagtcttgc tgtgtggccc     60

aggctggagt gcccggctgg tctcaaattc ctgacctcaa gtgatctccc tcccaaagtg    120

ttgcgattgc aggtgtgagc cactgcacct ggctgctgag aaatctttgc ctacagtgag    180

ggaaactact aaagttcctg gggaagcaaa gtagaatttc ataagaacaa aatggatgga    240

gaggagaaaa cctatggtgg ctgtgaagga cctgatgcca tgtatgtcaa attgatatca    300

tctgatggcc atgaatttat tgtaaaaaga gaacatgcat taacatcagg cacgataaaa    360

gccatgttga gtggcccagg tcagtttgct gagaacgaaa ccaatgaggt caattttaga    420

gagatacctt cacatgtgct atcgaaagta tgcatgtatt ttacgtacaa ggttcgctac    480

actaacagct ccaccgagat tcctgaattc ccaattgcac ctgaaattgc actggaactg    540

ctgatggctg cgaacttctt agattgttaa ataaaataaa ttataataaa ctgttaactc    600

ttttcagtat tt                                                        612


<210>  5747
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  5747

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Gly Gln Phe Ala Glu Asn Glu Thr Asn Glu Val Asn Phe Arg Glu 
    50                  55                  60


Ile Pro Ser His Val Leu Ser Lys Val Cys Met Tyr Phe Thr Tyr Lys 
65                  70                  75                  80


Val Arg Tyr Thr Asn Ser Ser Thr Glu Ile Pro Glu Phe Pro Ile Ala 
                85                  90                  95


Pro Glu Ile Ala Leu Glu Leu Leu Met Ala Ala Asn Phe Leu Asp Cys 
            100                 105                 110


<210>  5748
<211>  531
<212>  DNA
<213>  Homo sapiens

<400>  5748
actactaaag ttcctgggga agcaaagtag aatttcataa gaacaaaatg gatggagagg     60

agaaaaccta tggtggctgt gaaggacctg atgccatgta tgtcaaattg atatcatctg    120

atggccatga atttattgta aaaagagaac atgcattaac atcaggcacg ataaaagcca    180

tgttgagtgg cccagagaga cagagtctca ttctgttgcc caggctggag tgcaatggtg    240

cggtctcagc tcactgcaat ctccgcctgc tgggttcagg caattctcct gcctcagagt    300

agctggaatt acaggtcagt ttgctgagaa cgaaaccaat gaggtcaatt ttagagagat    360

accttcacat gtgctatcga aagtatgcat gtattttacg tacaaggttc gctacactaa    420

cagctccacc gagattcctg aattcccaat tgcacctgaa attgcactgg aactgctgat    480

ggctgcgaac ttcttagatt gttaaataaa ataaattata ataaactgtt a             531


<210>  5749
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  5749

Met Asp Gly Glu Glu Lys Thr Tyr Gly Gly Cys Glu Gly Pro Asp Ala 
1               5                   10                  15


Met Tyr Val Lys Leu Ile Ser Ser Asp Gly His Glu Phe Ile Val Lys 
            20                  25                  30


Arg Glu His Ala Leu Thr Ser Gly Thr Ile Lys Ala Met Leu Ser Gly 
        35                  40                  45


Pro Glu Arg Gln Ser Leu Ile Leu Leu Pro Arg Leu Glu Cys Asn Gly 
    50                  55                  60


Ala Val Ser Ala His Cys Asn Leu Arg Leu Leu Gly Ser Gly Asn Ser 
65                  70                  75                  80


Pro Ala Ser Glu 



<210>  5750
<211>  758
<212>  DNA
<213>  Homo sapiens

<400>  5750
ctgcgctcga cccggacgcc ggagaaggcg cgcggctccc gaaggccccg tactccagcc     60

ggctaccggc cccgaaggcc cgctgctgga ggacgcccgg gagacagagg cccggggacc    120

tcggagcgcg gcggccgcac acaatgcagt cctccttccg cagagaggca gttcgaccgc    180

ccacgggctt ctttataaca gtgtggaggg gcagagggct gtacgagaat gacaatgccc    240

agaagccagg gttaaatatt tttttttctc gtggacgaca tcactaaaaa ctgtttcctt    300

tgcggaaaat gattctagcc ataggaaacg cgggggggtg ggaagcgggg cgtggaatga    360

gaaagaagtt cccaaaaact gagtaacggt ttggcaggcg cctggatttt ctgtgcgtga    420

gctccggatc caggacagct gagctaaccc agaggcaaag gcaggaccct cgcgggtgga    480

gtgggggacg tggttagttt tcagttaaca ttgaattcta ccgggaagag aggaaatgag    540

gccagccgat tgcgctagtc gttgctgtgc tggctcttca gcacgcacag caacttttca    600

ccagggacag atgctgcttc ataaagagta cgatctcgtt agcaaagaaa ccgccctccc    660

acgtttcaat ctttcctcag cagtctccca cctccaggcg taaccctaaa tgagaggtac    720

ggacagtctc tgtaaccacc aaaatcttaa cacgcagt                            758


<210>  5751
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  5751

Met Gln Ser Ser Phe Arg Arg Glu Ala Val Arg Pro Pro Thr Gly Phe 
1               5                   10                  15


Phe Ile Thr Val Trp Arg Gly Arg Gly Leu Tyr Glu Asn Asp Asn Ala 
            20                  25                  30


Gln Lys Pro Gly Leu Asn Ile Phe Phe Ser Arg Gly Arg His His 
        35                  40                  45


<210>  5752
<211>  2067
<212>  DNA
<213>  Homo sapiens

<400>  5752
tatttttcac ctgtttaata acagtggttt tcctacaccc atagggtgcc accaagggag     60

gagtgcacag ttgcagaaac aaattaagat actgaagaca acactactta ccatttcccg    120

tatagctaac caccagttca actgtacatg tatgttctta tgggcaatca tgccaggggt    180

taggcaaaaa cctgtgttct gaaccaaaga agacttaaaa ctgctcccat aatttgtgaa    240

tttcttgaaa ttttgcggtt ttttgaaaat tttttaacaa ctggtaatca atttatgaaa    300

acagttgact taagcatttg caatggtgac ttccatctca actcctggct caatactgat    360

ggaagtaatc tgcttaacta tctgaggact gcgcaagtca atgagtcgct tgtggattct    420

catctggaaa cgatcccatg ccttagaacc ttcaccgtaa gtttttcttg tagtgattct    480

caaagtcttg gtaggcattc aaactggtcc tttcactgat tcttttcctt tgctcctcag    540

atcaagtcag cacacacctt atccagggat tttacgttgc aactcgttag agtgatatga    600

attcggtgaa ttgccacctc tgactccacg ggtgtttttc tggtatgttt aaaagccatg    660

gctgctgcaa ggcttcctag ccagcttcct gacagacttg gtcctcaggc aacagcaaag    720

agcagtgagt caggagcagg agcaggtgga ccacagctcc gcaccaccta tgactgtgtc    780

ttcctcaaag agaaaatgtc ttttaatgtc ggaaaatatt tatacactta gaaaaatcca    840

tacacaaaga ataaagcaac tctcccattt gctactgaca tcagatcccc agtttagagt    900

caaccacagt aacacagaac tcttatacta gcatgaacat atttattcac atacctttct    960

aaaacacgaa tggtagatac tacattttgg ttttcaaaca tagcttgttt tattataaac   1020

aaacatcatt ctctggaaat taaaagcttt gataatttca aattattttt aacaatcagt   1080

cactaacgga atgcaaaagg caattttatt attatacatt aaaacgtaaa tcacatttga   1140

gcacgaacac taacaaatag gctcatttgt catctttatg ccgtttctct tcactggttt   1200

cttccatata caaaataaat tcttctttgt cataacccat tagatggata tagtcttcac   1260

ggtttggaaa gagcactgga ttaactaaca gtgattttgt tttagcataa aatgtggtaa   1320

atacatgttt agcatctgga atcttcacat cattctggtg aaacactgta ctcgtttctg   1380

caagcatagc attgtaggta atggctttat aagtgtctgt tgtggcctca tggtacaatc   1440

gaatgacata gccttttgta ataaagtgaa gcagcactgg ggtgatcacc gtaaagcttc   1500

ccatgatgcc atagaatatg atttgaatag gcagaggcac actttcagaa atagcattat   1560

tttgtgtaaa aatgtatggc agaaatgtaa ggccaatcag actcgtagaa taagagaaac   1620

atttcacacc aaacactgct cgggccatat tgccagtata aattagcctt ccatcttctg   1680

atttgtcaga tggcgtattt aagaatcgaa catatccttc ccaataaaca gggatctgcg   1740

ctcgacccgg acgccggaga aggcgcgcgg ctcccgaagg ccccgtactc cagccggcta   1800

ccggccccga aggcccgctg ctggaggacg cccgggagac agaggcccgg ggacctcgga   1860

gcgcggcggc cgcacacaat gcagtcctcc ttccgcagag aggcagttcg accgcccacg   1920

ggctgcccaa cgccagaaac agcatcacgc gggtgacgag cggctgcgga cgccccagct   1980

gcacgagtcc acgactgcga gacacggctt cccacccgac tgccgcacaa gtggcgcatg   2040

cccagcccgg gacgcctgac tggcagc                                       2067


<210>  5753
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  5753

Met Phe Ser Ile Trp Asn Leu His Ile Ile Leu Val Lys His Cys Thr 
1               5                   10                  15


Arg Phe Cys Lys His Ser Ile Val Gly Asn Gly Phe Ile Ser Val Cys 
            20                  25                  30


Cys Gly Leu Met Val Gln Ser Asn Asp Ile Ala Phe Cys Asn Lys Val 
        35                  40                  45


Lys Gln His Trp Gly Asp His Arg Lys Ala Ser His Asp Ala Ile Glu 
    50                  55                  60


Tyr Asp Leu Asn Arg Gln Arg His Thr Phe Arg Asn Ser Ile Ile Leu 
65                  70                  75                  80


Cys Lys Asn Val Trp Gln Lys Cys Lys Ala Asn Gln Thr Arg Arg Ile 
                85                  90                  95


Arg Glu Thr Phe His Thr Lys His Cys Ser Gly His Ile Ala Ser Ile 
            100                 105                 110


Asn 



<210>  5754
<211>  1053
<212>  DNA
<213>  Homo sapiens

<400>  5754
cttatactag catgaacata tttattcaca tacctttcta aaacacgaat ggtagatact     60

acattttggt tttcaaacat agcttgtttt attataaaca aacatcattc tctggaaatt    120

aaaagctttg ataatttcaa attattttta acaatcagtc actaacggaa tgcaaaaggc    180

aattttatta ttatacatta aaacgtaaat cacatttgag cacgaacact aacaaatagg    240

ctcatttgtc atctttatgc cgtttctctt cactggtttc ttccatatac aaaataaatt    300

cttctttgtc ataacccatt agatggatat agtcttcacg gtttggaaag agcactggat    360

taactaacag tgattttgtt ttagcataaa atgtggtaaa tacatgttta gcatctggaa    420

tcttcacatc attctggtga aacactgtac tcgtttctgc aagcatagca ttgtaggtaa    480

tggctttata agtgtctgtt gtggcctcat ggtacaatcg aatgacatag ccttttgtaa    540

taaagtgaag cagcactggg gtgatcaccg taaagcttcc catgatgcca tagaatatga    600

tttgaatagg cagaggcaca ctttcagaaa tagcattatt ttgtgtaaaa atgtatggca    660

gaaatgtaag gccaatcaga ctcgtagaat aagagaaaca tttcacacca aacactgctc    720

gggccatatt gccagtataa attagccttc catcttctga tttgtcagat ggcgtattta    780

agaatcgaac atatccttcc caataaacag ggatccggct accggccccg aaggcccgct    840

gctggaggac gcccgggaga cagaggcccg gggacctcgg agcgcggcgg ccgcacacaa    900

tgcagtcctc cttccgcaga gaggcagttc gaccgcccac gggctgccca acgccagaaa    960

cagcatcacg cgggtgacga gcggctgcgg acgccccagc tgcacgagtc cacgactgcg   1020

agacacggct tcccacccga ctgccgcaca agt                                1053


<210>  5755
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  5755

Met Phe Ser Ile Trp Asn Leu His Ile Ile Leu Val Lys His Cys Thr 
1               5                   10                  15


Arg Phe Cys Lys His Ser Ile Val Gly Asn Gly Phe Ile Ser Val Cys 
            20                  25                  30


Cys Gly Leu Met Val Gln Ser Asn Asp Ile Ala Phe Cys Asn Lys Val 
        35                  40                  45


Lys Gln His Trp Gly Asp His Arg Lys Ala Ser His Asp Ala Ile Glu 
    50                  55                  60


Tyr Asp Leu Asn Arg Gln Arg His Thr Phe Arg Asn Ser Ile Ile Leu 
65                  70                  75                  80


Cys Lys Asn Val Trp Gln Lys Cys Lys Ala Asn Gln Thr Arg Arg Ile 
                85                  90                  95


Arg Glu Thr Phe His Thr Lys His Cys Ser Gly His Ile Ala Ser Ile 
            100                 105                 110


Asn 



<210>  5756
<211>  1204
<212>  DNA
<213>  Homo sapiens

<400>  5756
cttatactag catgaacata tttattcaca tacctttcta aaacacgaat ggtagatact     60

acattttggt tttcaaacat agcttgtttt attataaaca aacatcattc tctggaaatt    120

aaaagctttg ataatttcaa attattttta acaatcagtc actaacggaa tgcaaaaggc    180

aattttatta ttatacatta aaacgtaaat cacatttgag cacgaacact aacaaatagg    240

ctcatttgtc atctttatgc cgtttctctt cactggtttc ttccatatac aaaataaatt    300

cttctttgtc ataacccatt agatggatat agtcttcacg gtttggaaag agcactggat    360

taactaacag tgattttgtt ttagcataaa atgtggtaaa tacatgttta gcatctggaa    420

tcttcacatc attctggtga aacactgtac tcgtttctgc aagcatagca ttgtaggtaa    480

tggctttata agtgtctgtt gtggcctcat ggtacaatcg aatgacatag ccttttgtaa    540

taaagtgaag cagcactggg gtgatcaccg taaagcttcc catgatgcca tagaatatga    600

tttgaatagg cagaggcaca ctttcagaaa tagcattatt ttgtgtaaaa atgtatggca    660

gaaatgtaag gccaatcaga ctcgtagaat aagagaaaca tttcacacct gtaatcccag    720

caggaggctg agccaggaga atcgcttgaa catgggaggc gaagagtatg gtgaaccaag    780

atcatgccac tgcactccag ccaaacactg ctcgggccat attgccagta taaattagcc    840

ttccatcttc tgatttgtca gatggcgtat ttaagaatcg aacatatcct tcccaataaa    900

cagggatctg cgctcgaccc ggacgccgga gaaggcgcgc ggctcccgaa ggccccgtac    960

tccagccggc taccggcccc gaaggcccgc tgctggagga cgcccgggag acagaggccc   1020

ggggacctcg gagcgcggcg gccgcacaca atgcagtcct ccttccgcag agaggcagtt   1080

cgaccgccca cgggctgccc aacgccagaa acagcatcac gcgggtgacg agcggctgcg   1140

gacgccccag ctgcacgagt ccacgactgc gagacacggc ttcccacccg actgccgcac   1200

aagt                                                                1204


<210>  5757
<211>  144
<212>  PRT
<213>  Homo sapiens

<400>  5757

Met Phe Ser Ile Trp Asn Leu His Ile Ile Leu Val Lys His Cys Thr 
1               5                   10                  15


Arg Phe Cys Lys His Ser Ile Val Gly Asn Gly Phe Ile Ser Val Cys 
            20                  25                  30


Cys Gly Leu Met Val Gln Ser Asn Asp Ile Ala Phe Cys Asn Lys Val 
        35                  40                  45


Lys Gln His Trp Gly Asp His Arg Lys Ala Ser His Asp Ala Ile Glu 
    50                  55                  60


Tyr Asp Leu Asn Arg Gln Arg His Thr Phe Arg Asn Ser Ile Ile Leu 
65                  70                  75                  80


Cys Lys Asn Val Trp Gln Lys Cys Lys Ala Asn Gln Thr Arg Arg Ile 
                85                  90                  95


Arg Glu Thr Phe His Thr Cys Asn Pro Ser Arg Arg Leu Ser Gln Glu 
            100                 105                 110


Asn Arg Leu Asn Met Gly Gly Glu Glu Tyr Gly Glu Pro Arg Ser Cys 
        115                 120                 125


His Cys Thr Pro Ala Lys His Cys Ser Gly His Ile Ala Ser Ile Asn 
    130                 135                 140


<210>  5758
<211>  539
<212>  DNA
<213>  Homo sapiens

<400>  5758
acatcttatc aacacacctc aagaaaaaaa aatgaaaatc taattttcct tacgtcttgt     60

aattaaggga tgccataaca acaagtaaga tatggtaagg atatttttac aattaaaaga    120

gaaaaaaaca aagtaagtac acccacctcc aattacttac caaacactgc tcgggccata    180

ttgccagtat aaattagcct tccatcttct gatttgtcag atggcgtatt taagaatcga    240

acatatcctt cccaataaac agggatctgc gctcgacccg gacgccggag aaggcgcgcg    300

gctcccgaag gccccgtact ccagccggct accggccccg aaggcccgct gctggaggac    360

gcccgggaga cagaggcccg gggacctcgg agcgcggcgg ccgcacacaa tgcagtcctc    420

cttccgcaga gaggcagttc gaccgcccac gggctgccca acgccagaaa cagcatcacg    480

cgggtgacga gcggctgcgg acgccccagc tgcacgagtc cacgactgcg agacacggc     539


<210>  5759
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  5759

Met Ala Tyr Leu Arg Ile Glu His Ile Leu Pro Asn Lys Gln Gly Ser 
1               5                   10                  15


Ala Leu Asp Pro Asp Ala Gly Glu Gly Ala Arg Leu Pro Lys Ala Pro 
            20                  25                  30


Tyr Ser Ser Arg Leu Pro Ala Pro Lys Ala Arg Cys Trp Arg Thr Pro 
        35                  40                  45


Gly Arg Gln Arg Pro Gly Asp Leu Gly Ala Arg Arg Pro His Thr Met 
    50                  55                  60


Gln Ser Ser Phe Arg Arg Glu Ala Val Arg Pro Pro Thr Gly Cys Pro 
65                  70                  75                  80


Thr Pro Glu Thr Ala Ser Arg Gly 
                85


<210>  5760
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  5760
tataacattt tatttttttc ttctcagcaa ggcagtttac ttctatagaa gggggcgccc     60

tcacagatgg agcaatgccg tgaagaggat gccctgcaga ctcactgccc accggctccc    120

tcccccgcat ccctgcaacc ccagaggcga agatggcctc aggagtgcaa gtagctgatg    180

aagtatgtcg cattttttat gacatgaaag ttcgtaaatg ctccacacca gaagaaatca    240

agaaaagaaa gaaggctgtc attttttgtc tcggtgcaga cgaaaagtgc atcattgtag    300

aagaaggcaa agagatcttg gttggagatg ttggtgtaac cataactggt cctttcaagc    360

attttgtggg aatgcttcct gaaaaagatt gtcgctgtgc tttgtatgat gcaagctttg    420

aaacaaaaga atccagtaca gaagagttga tttttttttt gtaggcatga gaactagcac    480

ctctgaaaag taaaatgatc tgtgcaacat ccaaggatgc aatgaaaaag aaatttcaag    540

gca                                                                  543


<210>  5761
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  5761

Met Glu Gln Cys Arg Glu Glu Asp Ala Leu Gln Thr His Cys Pro Pro 
1               5                   10                  15


Ala Pro Ser Pro Ala Ser Leu Gln Pro Gln Arg Arg Arg Trp Pro Gln 
            20                  25                  30


Glu Cys Lys 
        35


<210>  5762
<211>  622
<212>  DNA
<213>  Homo sapiens

<400>  5762
agaaatcatg tgactgatga ctaagttaaa tcttttctgc ttactgaaaa ggaagagtct     60

gatgattagt tactgatcct ctttgcattt gtaaagcttt ggagatattg aatcatgtta    120

ccatttctgt ttttttccac cctgttttct tccatattta ctgaagctca gaagcagtat    180

tgggtctgca actcatccga tgcaagtatt tcatacacct actgtgataa aatgcaatac    240

ccaatttcaa ttaatgttaa cccctgtata gaattgaaaa gatccaaagg attattgcac    300

attttctaca ttccaaggag agatttaaag caattatatt tcaatctcta tataactgtc    360

aacaccatga atcttccaaa gcgcaaagaa gttatttgcc gaggatctga tgacgattac    420

tctttttgca gagctctgaa gggagagact gtgaatacaa caatatcatt ctccttcaag    480

ggaataaaat tttctaaggg aaaatacaaa tgtgttgttg aagctatttc tgggagccca    540

gaagaaatgc tcttttgctt ggagtttgtc atcctacacc aacctaattc aaattagaat    600

aaattgagta tttaaaaaaa aa                                             622


<210>  5763
<211>  160
<212>  PRT
<213>  Homo sapiens

<400>  5763

Met Leu Pro Phe Leu Phe Phe Ser Thr Leu Phe Ser Ser Ile Phe Thr 
1               5                   10                  15


Glu Ala Gln Lys Gln Tyr Trp Val Cys Asn Ser Ser Asp Ala Ser Ile 
            20                  25                  30


Ser Tyr Thr Tyr Cys Asp Lys Met Gln Tyr Pro Ile Ser Ile Asn Val 
        35                  40                  45


Asn Pro Cys Ile Glu Leu Lys Arg Ser Lys Gly Leu Leu His Ile Phe 
    50                  55                  60


Tyr Ile Pro Arg Arg Asp Leu Lys Gln Leu Tyr Phe Asn Leu Tyr Ile 
65                  70                  75                  80


Thr Val Asn Thr Met Asn Leu Pro Lys Arg Lys Glu Val Ile Cys Arg 
                85                  90                  95


Gly Ser Asp Asp Asp Tyr Ser Phe Cys Arg Ala Leu Lys Gly Glu Thr 
            100                 105                 110


Val Asn Thr Thr Ile Ser Phe Ser Phe Lys Gly Ile Lys Phe Ser Lys 
        115                 120                 125


Gly Lys Tyr Lys Cys Val Val Glu Ala Ile Ser Gly Ser Pro Glu Glu 
    130                 135                 140


Met Leu Phe Cys Leu Glu Phe Val Ile Leu His Gln Pro Asn Ser Asn 
145                 150                 155                 160


<210>  5764
<211>  614
<212>  DNA
<213>  Homo sapiens

<400>  5764
tatttctgta aattgttgtg ttagtggagg caagaagagt tcagggcttc tgattctgcc     60

acattgctga tgtcattctt ctggggagat attttcaatc atcatcaatt tttcttattt    120

tataatttta atgcaagatt catcttaaaa ggctgatatt cagaatacta tacttaatgg    180

agatgatttg tagtaattta ttgacattat ctttattgct tttagataaa atgcaatacc    240

caatttcaat taatgttaac ccctgtatag aattgaaaag atccaaagga ttattgcaca    300

ttttctacat tccaaggaga gatttaaagc aattatattt caatctctat ataactgtca    360

acaccatgaa tcttccaaag cgcaaagaag ttatttgccg aggatctgat gacgattact    420

ctttttgcag agctctgaag ggagagactg tgaatacaac aatatcattc tccttcaagg    480

gaataaaatt ttctaaggga aaatacaaat gtgttgttga agctatttct gggagcccag    540

aagaaatgct cttttgcttg gagtttgtca tcctacacca acctaattca aattagaata    600

aattgagtat ttaa                                                      614


<210>  5765
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  5765

Met Glu Met Ile Cys Ser Asn Leu Leu Thr Leu Ser Leu Leu Leu Leu 
1               5                   10                  15


Asp Lys Met Gln Tyr Pro Ile Ser Ile Asn Val Asn Pro Cys Ile Glu 
            20                  25                  30


Leu Lys Arg Ser Lys Gly Leu Leu His Ile Phe Tyr Ile Pro Arg Arg 
        35                  40                  45


Asp Leu Lys Gln Leu Tyr Phe Asn Leu Tyr Ile Thr Val Asn Thr Met 
    50                  55                  60


Asn Leu Pro Lys Arg Lys Glu Val Ile Cys Arg Gly Ser Asp Asp Asp 
65                  70                  75                  80


Tyr Ser Phe Cys Arg Ala Leu Lys Gly Glu Thr Val Asn Thr Thr Ile 
                85                  90                  95


Ser Phe Ser Phe Lys Gly Ile Lys Phe Ser Lys Gly Lys Tyr Lys Cys 
            100                 105                 110


Val Val Glu Ala Ile Ser Gly Ser Pro Glu Glu Met Leu Phe Cys Leu 
        115                 120                 125


Glu Phe Val Ile Leu His Gln Pro Asn Ser Asn 
    130                 135


<210>  5766
<211>  512
<212>  DNA
<213>  Homo sapiens

<400>  5766
aaagaagttt ctgctgttta taagataccc tcatttatgg tgttttgtta ttcagatcga     60

acagactagg aaatagtatg gaaataccag aaaggaacca gggtccggtt gcggctatta    120

gatcttgaac ttacgtctag gttcctggga gcaacaacag atacaactgt actagaggct    180

aatgcagttc tcttgggaat ccaggagagt aaagactcaa gatcgaaaga agaacatcat    240

gaaaaataaa tgaactttgc ttagtggatt gactcctttg ctgaagtcag ttattcatca    300

agaatgcaat tagactaatt gtgaataaat gattgaatga agatataata aataaaagct    360

ataattatag ataactctta ttagaatttt ctttagcaat attcccaccc cccacccctt    420

gttttgctct taatgttttt ttcctttggt ggggatagta tacactgtac taagaaattg    480

tcattcaata aatacgtttt gagtgctgtc ta                                  512


<210>  5767
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5767

Glu Ile Val Trp Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu 
1               5                   10                  15


Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr 
            20                  25                  30


Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys 
        35                  40                  45


Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
    50                  55


<210>  5768
<211>  720
<212>  DNA
<213>  Homo sapiens

<400>  5768
cctggacttc cagcctctag aactatgaga aagaagtttc tgctgtttat aagataccct     60

catttatggt gttttgttat tcagatcgaa cagactagga aatagtatgg agtcccattt    120

cgtggtatgc tgtttggagg agattttcac aagtgatgat aacctgtttt tcttccaact    180

ctgactttgg aaaacatcgt aaaagataaa gaagttgtaa tacaacatgg atgaaccctg    240

aaaacattat gccaaatgaa agaagccatt cacaaaagat catatattga aataccagaa    300

aggaaccagg gtccggttgc ggctattaga tcttgaactt acgtctaggt tcctgggagc    360

aacaacagat acaactgtac tagaggctaa tgcagttctc ttgggaatcc aggagagtaa    420

agactcaaga tcgaaagaag aacatcatga aaaataaatg aactttgctt agtggattga    480

ctcctttgct gaagtcagtt attcatcaag aatgcaatta gactaattgt gaataaatga    540

ttgaatgaag atataataaa taaaagctat aattatagat aactcttatt agaattttct    600

ttagcaatat tcccaccccc caccccttgt tttgctctta atgttttttt cctttggtgg    660

ggatagtata cactgtacta agaaattgtc attcaataaa tacgttttga gtgctgtcta    720


<210>  5769
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  5769

Lys Lys Pro Phe Thr Lys Asp His Ile Leu Lys Tyr Gln Lys Gly Thr 
1               5                   10                  15


Arg Val Arg Leu Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu 
            20                  25                  30


Gly Ala Thr Thr Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu 
        35                  40                  45


Gly Ile Gln Glu Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu 
    50                  55                  60


Lys 
65


<210>  5770
<211>  808
<212>  DNA
<213>  Homo sapiens

<400>  5770
gagttgcggt gcgttgtggc tcagccctcg gcccctagaa tctgtgcttg gtgtttttct     60

tcctttcgtt gtccttttgt gtggcatttg cgtactgggc cgggtctgtc cacactgcgc    120

ttgttttcct gggattgaat gctggtggga agagatgggg ttttgccatg ttgcccaggc    180

tggtcttgaa ctcctgggtt caagtgatcc tcctgcgttg gcctcccaaa gtgctgggat    240

tacagatgac agatatggga cctgcaaagg ataaactggt cattggacgg atctttcata    300

ttgtggagaa tgatctgtac atagattttg gtggaaagtt tcattgtgta tgtagaagac    360

cagaagtgga tggagagaaa taccagaaag gaaccagggt ccggttgcgg ctattagatc    420

ttgaacttac gtctaggttc ctgggagcaa caacagatac aactgtacta gaggctaatg    480

cagttctctt gggaatccag gagagtaaag actcaagatc gaaagaagaa catcatgaaa    540

aataaatgaa ctttgcttag tggattgact cctttgctga agtcagttat tcatcaagaa    600

tgcaattaga ctaattgtga ataaatgatt gaatgaagat ataataaata aaagctataa    660

ttatagataa ctcttattag aattttcttt agcaatattc ccacccccca ccccttgttt    720

tgctcttaat gtttttttcc tttggtgggg atagtataca ctgtactaag aaattgtcat    780

tcaataaata cgttttgagt gctgtcta                                       808


<210>  5771
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5771

Met Leu Pro Arg Leu Val Leu Asn Ser Trp Val Gln Val Ile Leu Leu 
1               5                   10                  15


Arg Trp Pro Pro Lys Val Leu Gly Leu Gln Met Thr Asp Met Gly Pro 
            20                  25                  30


Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn 
        35                  40                  45


Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg 
    50                  55                  60


Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu 
65                  70                  75                  80


Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr 
                85                  90                  95


Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu 
            100                 105                 110


Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
        115                 120                 125


<210>  5772
<211>  675
<212>  DNA
<213>  Homo sapiens

<400>  5772
ggggcggagc ctggcttagg aaggggagct gaggtccggg gcccagtttt ccggagttgc     60

gggttctcca aaaaatgtgg aatcctttgc atctatgctg agacattctc ctcttacaca    120

gatgggacct gcaaaggata aactggtcat tggacggatc tttcatattg tggagaatga    180

tctgtacata gattttggtg gaaagtttca ttgtgtatgt agaagaccag aagtggatgg    240

agagaaatac cagaaaggaa ccagggtccg gttgcggcta ttagatcttg aacttacgtc    300

taggttcctg ggagcaacaa cagatacaac tgtactagag gctaatgcag ttctcttggg    360

aatccaggag agtaaagact caagatcgaa agaagaacat catgaaaaat aaatgaactt    420

tgcttagtgg attgactcct ttgctgaagt cagttattca tcaagaatgc aattagacta    480

attgtgaata aatgattgaa tgaagatata ataaataaaa gctataatta tagataactc    540

ttattagaat tttctttagc aatattccca ccccccaccc cttgttttgc tcttaatgtt    600

tttttccttt ggtggggata gtatacactg tactaagaaa ttgtcattca ataaatacgt    660

tttgagtgct gtcta                                                     675


<210>  5773
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  5773

Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys Asp Lys 
1               5                   10                  15


Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu Tyr Ile 
            20                  25                  30


Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu Val Asp 
        35                  40                  45


Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu Leu Asp 
    50                  55                  60


Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr Thr Val 
65                  70                  75                  80


Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys Asp Ser 
                85                  90                  95


Arg Ser Lys Glu Glu His His Glu Lys 
            100                 105


<210>  5774
<211>  726
<212>  DNA
<213>  Homo sapiens

<400>  5774
tcgggaatag gggcggagcc tggcttagga aggggagctg aggtccgggg cccagttttc     60

cggagttgcg agatggggtt ttgccatgtt gcccaggctg gtcttgaact cctgggttca    120

agtgatcctc ctgcgttggc ctcccaaagt gctgggatta cagatgacag atatgggacc    180

tgcaaaggat aaactggtca ttggacggat ctttcatatt gtggagaatg atctgtacat    240

agattttggt ggaaagtttc attgtgtatg tagaagacca gaagtggatg gagagaaata    300

ccagaaagga accagggtcc ggttgcggct attagatctt gaacttacgt ctaggttcct    360

gggagcaaca acagatacaa ctgtactaga ggctaatgca gttctcttgg gaatccagga    420

gagtaaagac tcaagatcga aagaagaaca tcatgaaaaa taaatgaact ttgcttagtg    480

gattgactcc tttgctgaag tcagttattc atcaagaatg caattagact aattgtgaat    540

aaatgattga atgaagatat aataaataaa agctataatt atagataact cttattagaa    600

ttttctttag caatattccc accccccacc ccttgttttg ctcttaatgt ttttttcctt    660

tggtggggat agtatacact gtactaagaa attgtcattc aataaatacg ttttgagtgc    720

tgtcta                                                               726


<210>  5775
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5775

Met Leu Pro Arg Leu Val Leu Asn Ser Trp Val Gln Val Ile Leu Leu 
1               5                   10                  15


Arg Trp Pro Pro Lys Val Leu Gly Leu Gln Met Thr Asp Met Gly Pro 
            20                  25                  30


Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn 
        35                  40                  45


Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg 
    50                  55                  60


Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu 
65                  70                  75                  80


Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr 
                85                  90                  95


Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu 
            100                 105                 110


Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
        115                 120                 125


<210>  5776
<211>  764
<212>  DNA
<213>  Homo sapiens

<400>  5776
agaggtaaag aagtcatggc ggcgctgtgt cggacccgtg ctgtggctgc cgagagccat     60

tttctgcgag tgtttctctt cttcaggccc tttcggggtg taggcactga gagtggatcc    120

gaaagtggta gttccaatgc caaggagcct aagacgcgcg caggcggttt cgcgagcgcg    180

ttggagcggc actcggagct tctacagaag atgggacctg caaaggataa actggtcatt    240

ggacggatct ttcatattgt ggagaatgat ctgtacatag attttggtgg aaagtttcat    300

tgtgtatgta gaagaccaga agtggatgga gagaaatacc agaaaggaac cagggtccgg    360

ttgcggctat tagatcttga acttacgtct aggttcctgg gagcaacaac agatacaact    420

gtactagagg ctaatgcagt tctcttggga atccaggaga gtaaagactc aagatcgaaa    480

gaagaacatc atgaaaaata aatgaacttt gcttagtgga ttgactcctt tgctgaagtc    540

agttattcat caagaatgca attagactaa ttgtgaataa atgattgaat gaagatataa    600

taaataaaag ctataattat agataactct tattagaatt ttctttagca atattcccac    660

cccccacccc ttgttttgct cttaatgttt ttttcctttg gtggggatag tatacactgt    720

actaagaaat tgtcattcaa taaatacgtt ttgagtgctg tcta                     764


<210>  5777
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  5777

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Met Gly Pro Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His 
65                  70                  75                  80


Ile Val Glu Asn Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys 
                85                  90                  95


Val Cys Arg Arg Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr 
            100                 105                 110


Arg Val Arg Leu Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu 
        115                 120                 125


Gly Ala Thr Thr Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu 
    130                 135                 140


Gly Ile Gln Glu Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu 
145                 150                 155                 160


Lys 



<210>  5778
<211>  661
<212>  DNA
<213>  Homo sapiens

<400>  5778
cagaggtaaa gaagtcatgg cggcgctgtg tcggacccgt gctgtggctg ccgagagcca     60

ttttctgcga gtgtttctct tcttcaggcc ctttcggggt gtaggcactg agagtggatc    120

cgaaagtggt agttccaatg ccaaggagcc taagacgcgc gcaggcggtt tcgcgagcgc    180

gttggagcgg cactcggagc ttctacagaa ggtggagccc ctacagaagg aaataccaga    240

aaggaaccag ggtccggttg cggctattag atcttgaact tacgtctagg ttcctgggag    300

caacaacaga tacaactgta ctagaggcta atgcagttct cttgggaatc caggagagta    360

aagactcaag atcgaaagaa gaacatcatg aaaaataaat gaactttgct tagtggattg    420

actcctttgc tgaagtcagt tattcatcaa gaatgcaatt agactaattg tgaataaatg    480

attgaatgaa gatataataa ataaaagcta taattataga taactcttat tagaattttc    540

tttagcaata ttcccacccc ccaccccttg ttttgctctt aatgtttttt tcctttggtg    600

gggatagtat acactgtact aagaaattgt cattcaataa atacgttttg agtgctgtct    660

a                                                                    661


<210>  5779
<211>  86
<212>  PRT
<213>  Homo sapiens

<400>  5779

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Val Glu Pro Leu Gln Lys Glu Ile Pro Glu Arg Asn Gln Gly Pro 
65                  70                  75                  80


Val Ala Ala Ile Arg Ser 
                85


<210>  5780
<211>  861
<212>  DNA
<213>  Homo sapiens

<400>  5780
ggaggggagg tcaaaggtca gaggtaaaga agtcatggcg gcgctgtgtc ggacccgtgc     60

tgtggctgcc gagagccatt ttctgcgagt gtttctcttc ttcaggccct ttcggggtgt    120

aggcactgag agtggatccg aaagtggtag ttccaatgcc aaggagccta agacgcgcgc    180

aggcggtttc gcgagcgcgt tggagcggca ctcggagctt ctacagaagg tggagcccct    240

acagaagggt tctccaaaaa atgtggaatc ctttgcatct atgctgagac attctcctct    300

tacacagatg ggacctgcaa aggataaact ggtcattgga cggatctttc atattgtgga    360

gaatgatctg tacatagatt ttggtggaaa gtttcattgt gtatgtagaa gaccagaagt    420

ggatggagag aaataccaga aaggaaccag ggtccggttg cggctattag atcttgaact    480

tacgtctagg ttcctgggag caacaacaga tacaactgta ctagaggcta atgcagttct    540

cttgggaatc caggagagta aagactcaag atcgaaagaa gaacatcatg aaaaataaat    600

gaactttgct tagtggattg actcctttgc tgaagtcagt tattcatcaa gaatgcaatt    660

agactaattg tgaataaatg attgaatgaa gatataataa ataaaagcta taattataga    720

taactcttat tagaattttc tttagcaata ttcccacccc ccaccccttg ttttgctctt    780

aatgtttttt tcctttggtg gggatagtat acactgtact aagaaattgt cattcaataa    840

atacgttttg agtgctgtct a                                              861


<210>  5781
<211>  187
<212>  PRT
<213>  Homo sapiens

<400>  5781

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Val Glu Pro Leu Gln Lys Gly Ser Pro Lys Asn Val Glu Ser Phe 
65                  70                  75                  80


Ala Ser Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys 
                85                  90                  95


Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu 
            100                 105                 110


Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu 
        115                 120                 125


Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu 
    130                 135                 140


Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr 
145                 150                 155                 160


Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys 
                165                 170                 175


Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
            180                 185


<210>  5782
<211>  372
<212>  DNA
<213>  Homo sapiens

<400>  5782
aaagaagttt ctgctgttta taagataccc tcatttatgg tgttttgtta ttcagatcga     60

acagactagg aaatagtatg gaaataccag aaaggaacca gggtccggtt gcggctatta    120

gatcttgaac ttacgtctag gttcctggga gcaacaacag atacaactgt actagaggct    180

aatgcagttc tcttgggaat ccaggagagt aaagactcaa gatcgaaaga agaacatcat    240

gaaaaataaa tgaactttgc ttagtggatt gactcctttg ctgaagtcag ttattcatca    300

agaatgcaat tagactaatt gtgaataaat gattgaatga agatataata aataaaagct    360

ataattatag at                                                        372


<210>  5783
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5783

Glu Ile Val Trp Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu 
1               5                   10                  15


Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr 
            20                  25                  30


Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys 
        35                  40                  45


Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
    50                  55


<210>  5784
<211>  580
<212>  DNA
<213>  Homo sapiens

<400>  5784
cctggacttc cagcctctag aactatgaga aagaagtttc tgctgtttat aagataccct     60

catttatggt gttttgttat tcagatcgaa cagactagga aatagtatgg agtcccattt    120

cgtggtatgc tgtttggagg agattttcac aagtgatgat aacctgtttt tcttccaact    180

ctgactttgg aaaacatcgt aaaagataaa gaagttgtaa tacaacatgg atgaaccctg    240

aaaacattat gccaaatgaa agaagccatt cacaaaagat catatattga aataccagaa    300

aggaaccagg gtccggttgc ggctattaga tcttgaactt acgtctaggt tcctgggagc    360

aacaacagat acaactgtac tagaggctaa tgcagttctc ttgggaatcc aggagagtaa    420

agactcaaga tcgaaagaag aacatcatga aaaataaatg aactttgctt agtggattga    480

ctcctttgct gaagtcagtt attcatcaag aatgcaatta gactaattgt gaataaatga    540

ttgaatgaag atataataaa taaaagctat aattatagat                          580


<210>  5785
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  5785

Lys Lys Pro Phe Thr Lys Asp His Ile Leu Lys Tyr Gln Lys Gly Thr 
1               5                   10                  15


Arg Val Arg Leu Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu 
            20                  25                  30


Gly Ala Thr Thr Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu 
        35                  40                  45


Gly Ile Gln Glu Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu 
    50                  55                  60


Lys 
65


<210>  5786
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  5786
cttttgtgtg gcatttgcgt actgggccgg gtctgtccac actgcgcttg ttttcctggg     60

attgaatgct ggtgggaagg gttctccaaa aaatgtggaa tcctttgcat ctatgctgag    120

acattctcct cttacacaga tgggacctgc aaaggataaa ctggtcattg gacggatctt    180

tcatattgtg gagaatgatc tgtacataga ttttggtgga aagtttcatt gtgtatgtag    240

aagaccagaa gtggatggag agaaatacca gaaaggaacc agggtccggt tgcggctatt    300

agatcttgaa cttacgtcta ggttcctggg agcaacaaca gatacaactg tactagaggc    360

taatgcagtt ctcttgggaa tccaggagag taaagactca agatcgaaag aagaacatca    420

tgaaaaataa atgaactttg cttagtggat tgactccttt gctgaagtca gttattcatc    480

aagaatgcaa ttagactaat tgtgaataaa tgattgaatg aagatataat aaataaaagc    540

tataattata gat                                                       553


<210>  5787
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  5787

Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys Asp Lys 
1               5                   10                  15


Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu Tyr Ile 
            20                  25                  30


Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu Val Asp 
        35                  40                  45


Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu Leu Asp 
    50                  55                  60


Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr Thr Val 
65                  70                  75                  80


Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys Asp Ser 
                85                  90                  95


Arg Ser Lys Glu Glu His His Glu Lys 
            100                 105


<210>  5788
<211>  668
<212>  DNA
<213>  Homo sapiens

<400>  5788
gagttgcggt gcgttgtggc tcagccctcg gcccctagaa tctgtgcttg gtgtttttct     60

tcctttcgtt gtccttttgt gtggcatttg cgtactgggc cgggtctgtc cacactgcgc    120

ttgttttcct gggattgaat gctggtggga agagatgggg ttttgccatg ttgcccaggc    180

tggtcttgaa ctcctgggtt caagtgatcc tcctgcgttg gcctcccaaa gtgctgggat    240

tacagatgac agatatggga cctgcaaagg ataaactggt cattggacgg atctttcata    300

ttgtggagaa tgatctgtac atagattttg gtggaaagtt tcattgtgta tgtagaagac    360

cagaagtgga tggagagaaa taccagaaag gaaccagggt ccggttgcgg ctattagatc    420

ttgaacttac gtctaggttc ctgggagcaa caacagatac aactgtacta gaggctaatg    480

cagttctctt gggaatccag gagagtaaag actcaagatc gaaagaagaa catcatgaaa    540

aataaatgaa ctttgcttag tggattgact cctttgctga agtcagttat tcatcaagaa    600

tgcaattaga ctaattgtga ataaatgatt gaatgaagat ataataaata aaagctataa    660

ttatagat                                                             668


<210>  5789
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5789

Met Leu Pro Arg Leu Val Leu Asn Ser Trp Val Gln Val Ile Leu Leu 
1               5                   10                  15


Arg Trp Pro Pro Lys Val Leu Gly Leu Gln Met Thr Asp Met Gly Pro 
            20                  25                  30


Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn 
        35                  40                  45


Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg 
    50                  55                  60


Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu 
65                  70                  75                  80


Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr 
                85                  90                  95


Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu 
            100                 105                 110


Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
        115                 120                 125


<210>  5790
<211>  535
<212>  DNA
<213>  Homo sapiens

<400>  5790
ggggcggagc ctggcttagg aaggggagct gaggtccggg gcccagtttt ccggagttgc     60

gggttctcca aaaaatgtgg aatcctttgc atctatgctg agacattctc ctcttacaca    120

gatgggacct gcaaaggata aactggtcat tggacggatc tttcatattg tggagaatga    180

tctgtacata gattttggtg gaaagtttca ttgtgtatgt agaagaccag aagtggatgg    240

agagaaatac cagaaaggaa ccagggtccg gttgcggcta ttagatcttg aacttacgtc    300

taggttcctg ggagcaacaa cagatacaac tgtactagag gctaatgcag ttctcttggg    360

aatccaggag agtaaagact caagatcgaa agaagaacat catgaaaaat aaatgaactt    420

tgcttagtgg attgactcct ttgctgaagt cagttattca tcaagaatgc aattagacta    480

attgtgaata aatgattgaa tgaagatata ataaataaaa gctataatta tagat         535


<210>  5791
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  5791

Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys Asp Lys 
1               5                   10                  15


Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu Tyr Ile 
            20                  25                  30


Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu Val Asp 
        35                  40                  45


Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu Leu Asp 
    50                  55                  60


Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr Thr Val 
65                  70                  75                  80


Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys Asp Ser 
                85                  90                  95


Arg Ser Lys Glu Glu His His Glu Lys 
            100                 105


<210>  5792
<211>  586
<212>  DNA
<213>  Homo sapiens

<400>  5792
tcgggaatag gggcggagcc tggcttagga aggggagctg aggtccgggg cccagttttc     60

cggagttgcg agatggggtt ttgccatgtt gcccaggctg gtcttgaact cctgggttca    120

agtgatcctc ctgcgttggc ctcccaaagt gctgggatta cagatgacag atatgggacc    180

tgcaaaggat aaactggtca ttggacggat ctttcatatt gtggagaatg atctgtacat    240

agattttggt ggaaagtttc attgtgtatg tagaagacca gaagtggatg gagagaaata    300

ccagaaagga accagggtcc ggttgcggct attagatctt gaacttacgt ctaggttcct    360

gggagcaaca acagatacaa ctgtactaga ggctaatgca gttctcttgg gaatccagga    420

gagtaaagac tcaagatcga aagaagaaca tcatgaaaaa taaatgaact ttgcttagtg    480

gattgactcc tttgctgaag tcagttattc atcaagaatg caattagact aattgtgaat    540

aaatgattga atgaagatat aataaataaa agctataatt atagat                   586


<210>  5793
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  5793

Met Leu Pro Arg Leu Val Leu Asn Ser Trp Val Gln Val Ile Leu Leu 
1               5                   10                  15


Arg Trp Pro Pro Lys Val Leu Gly Leu Gln Met Thr Asp Met Gly Pro 
            20                  25                  30


Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn 
        35                  40                  45


Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg 
    50                  55                  60


Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu 
65                  70                  75                  80


Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr 
                85                  90                  95


Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu 
            100                 105                 110


Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
        115                 120                 125


<210>  5794
<211>  624
<212>  DNA
<213>  Homo sapiens

<400>  5794
agaggtaaag aagtcatggc ggcgctgtgt cggacccgtg ctgtggctgc cgagagccat     60

tttctgcgag tgtttctctt cttcaggccc tttcggggtg taggcactga gagtggatcc    120

gaaagtggta gttccaatgc caaggagcct aagacgcgcg caggcggttt cgcgagcgcg    180

ttggagcggc actcggagct tctacagaag atgggacctg caaaggataa actggtcatt    240

ggacggatct ttcatattgt ggagaatgat ctgtacatag attttggtgg aaagtttcat    300

tgtgtatgta gaagaccaga agtggatgga gagaaatacc agaaaggaac cagggtccgg    360

ttgcggctat tagatcttga acttacgtct aggttcctgg gagcaacaac agatacaact    420

gtactagagg ctaatgcagt tctcttggga atccaggaga gtaaagactc aagatcgaaa    480

gaagaacatc atgaaaaata aatgaacttt gcttagtgga ttgactcctt tgctgaagtc    540

agttattcat caagaatgca attagactaa ttgtgaataa atgattgaat gaagatataa    600

taaataaaag ctataattat agat                                           624


<210>  5795
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  5795

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Met Gly Pro Ala Lys Asp Lys Leu Val Ile Gly Arg Ile Phe His 
65                  70                  75                  80


Ile Val Glu Asn Asp Leu Tyr Ile Asp Phe Gly Gly Lys Phe His Cys 
                85                  90                  95


Val Cys Arg Arg Pro Glu Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr 
            100                 105                 110


Arg Val Arg Leu Arg Leu Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu 
        115                 120                 125


Gly Ala Thr Thr Asp Thr Thr Val Leu Glu Ala Asn Ala Val Leu Leu 
    130                 135                 140


Gly Ile Gln Glu Ser Lys Asp Ser Arg Ser Lys Glu Glu His His Glu 
145                 150                 155                 160


Lys 



<210>  5796
<211>  521
<212>  DNA
<213>  Homo sapiens

<400>  5796
cagaggtaaa gaagtcatgg cggcgctgtg tcggacccgt gctgtggctg ccgagagcca     60

ttttctgcga gtgtttctct tcttcaggcc ctttcggggt gtaggcactg agagtggatc    120

cgaaagtggt agttccaatg ccaaggagcc taagacgcgc gcaggcggtt tcgcgagcgc    180

gttggagcgg cactcggagc ttctacagaa ggtggagccc ctacagaagg aaataccaga    240

aaggaaccag ggtccggttg cggctattag atcttgaact tacgtctagg ttcctgggag    300

caacaacaga tacaactgta ctagaggcta atgcagttct cttgggaatc caggagagta    360

aagactcaag atcgaaagaa gaacatcatg aaaaataaat gaactttgct tagtggattg    420

actcctttgc tgaagtcagt tattcatcaa gaatgcaatt agactaattg tgaataaatg    480

attgaatgaa gatataataa ataaaagcta taattataga t                        521


<210>  5797
<211>  86
<212>  PRT
<213>  Homo sapiens

<400>  5797

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Val Glu Pro Leu Gln Lys Glu Ile Pro Glu Arg Asn Gln Gly Pro 
65                  70                  75                  80


Val Ala Ala Ile Arg Ser 
                85


<210>  5798
<211>  712
<212>  DNA
<213>  Homo sapiens

<400>  5798
gtcaaaggtc agaggtaaag aagtcatggc ggcgctgtgt cggacccgtg ctgtggctgc     60

cgagagccat tttctgcgag tgtttctctt cttcaggccc tttcggggtg taggcactga    120

gagtggatcc gaaagtggta gttccaatgc caaggagcct aagacgcgcg caggcggttt    180

cgcgagcgcg ttggagcggc actcggagct tctacagaag gtggagcccc tacagaaggg    240

ttctccaaaa aatgtggaat cctttgcatc tatgctgaga cattctcctc ttacacagat    300

gggacctgca aaggataaac tggtcattgg acggatcttt catattgtgg agaatgatct    360

gtacatagat tttggtggaa agtttcattg tgtatgtaga agaccagaag tggatggaga    420

gaaataccag aaaggaacca gggtccggtt gcggctatta gatcttgaac ttacgtctag    480

gttcctggga gcaacaacag atacaactgt actagaggct aatgcagttc tcttgggaat    540

ccaggagagt aaagactcaa gatcgaaaga agaacatcat gaaaaataaa tgaactttgc    600

ttagtggatt gactcctttg ctgaagtcag ttattcatca agaatgcaat tagactaatt    660

gtgaataaat gattgaatga agatataata aataaaagct ataattatag at            712


<210>  5799
<211>  187
<212>  PRT
<213>  Homo sapiens

<400>  5799

Met Ala Ala Leu Cys Arg Thr Arg Ala Val Ala Ala Glu Ser His Phe 
1               5                   10                  15


Leu Arg Val Phe Leu Phe Phe Arg Pro Phe Arg Gly Val Gly Thr Glu 
            20                  25                  30


Ser Gly Ser Glu Ser Gly Ser Ser Asn Ala Lys Glu Pro Lys Thr Arg 
        35                  40                  45


Ala Gly Gly Phe Ala Ser Ala Leu Glu Arg His Ser Glu Leu Leu Gln 
    50                  55                  60


Lys Val Glu Pro Leu Gln Lys Gly Ser Pro Lys Asn Val Glu Ser Phe 
65                  70                  75                  80


Ala Ser Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys 
                85                  90                  95


Asp Lys Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu 
            100                 105                 110


Tyr Ile Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu 
        115                 120                 125


Val Asp Gly Glu Lys Tyr Gln Lys Gly Thr Arg Val Arg Leu Arg Leu 
    130                 135                 140


Leu Asp Leu Glu Leu Thr Ser Arg Phe Leu Gly Ala Thr Thr Asp Thr 
145                 150                 155                 160


Thr Val Leu Glu Ala Asn Ala Val Leu Leu Gly Ile Gln Glu Ser Lys 
                165                 170                 175


Asp Ser Arg Ser Lys Glu Glu His His Glu Lys 
            180                 185


<210>  5800
<211>  406
<212>  DNA
<213>  Homo sapiens

<400>  5800
atggtggtgg taatctttaa gaagtttggc ataaacagta accaagtctt tggtcttcaa     60

tgcattctat gatgattctt tcaatgatgt aggtaataca gtaagatttt aaactgtaac    120

acaaacacac acatatacac acacacacaa gcacaattac aaaatgcctt cggatagatg    180

actagaaata aaaataattc cacaacattc taaaagcatc tttatcaata tagctaattt    240

aatgaataaa tgttatttgc catctgaagt aaaactttga gtttcagagc tttactttac    300

atcacaccag ctgaccttta agatgttgtt gaggacaagt cttaaccaat atcaaatgaa    360

taaatttctg ctgctattca tcctggagtc agatgtgaag tcagtc                   406


<210>  5801
<211>  622
<212>  DNA
<213>  Homo sapiens

<400>  5801
aaaaatgtgg aatcctttgc atctatgctg agacattctc ctcttacaca gatgggacct     60

gcaaaggata aactggtcat tggacggatc tttcatattg tggagaatga tctgtacata    120

gattttggtg gaaagtttca ttgtgtatgt agaagaccag aagtggatgg agagagtccc    180

atttcgtggt atgctgtttg gaggagattt tcacaagtga tgataacctg tttttcttcc    240

aactctgact ttggaaaaca tcgtaaaaga taaagaagtt gtaatacaac atggatgaac    300

cctgaaaaca ttatgccaaa tgaaagaagc cattcacaaa agatcatata ttgtatgatt    360

ccatttatat gaaatgttca gaatagacaa atccacagag acagaaagta gattagtcat    420

ccccagagtc tagaataggg gagggggaga gattgctaat gagtacaggg tttctttttt    480

ggggtgatga aaatgttcta aaattaggtt atggtaaaag ctgtacagct ctgagaatat    540

attcaaagtc actgaattat acactttggg tagattttat gatatgtgaa ttatatctca    600

ataaagctgt taaagtttta gt                                             622


<210>  5802
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  5802

Met Leu Arg His Ser Pro Leu Thr Gln Met Gly Pro Ala Lys Asp Lys 
1               5                   10                  15


Leu Val Ile Gly Arg Ile Phe His Ile Val Glu Asn Asp Leu Tyr Ile 
            20                  25                  30


Asp Phe Gly Gly Lys Phe His Cys Val Cys Arg Arg Pro Glu Val Asp 
        35                  40                  45


Gly Glu Ser Pro Ile Ser Trp Tyr Ala Val Trp Arg Arg Phe Ser Gln 
    50                  55                  60


Val Met Ile Thr Cys Phe Ser Ser Asn Ser Asp Phe Gly Lys His Arg 
65                  70                  75                  80


Lys Arg 



<210>  5803
<211>  2580
<212>  DNA
<213>  Homo sapiens

<400>  5803
aatgttatgc aagtgtagag acagacagtt cactaggtac tttaaaataa tagaccttac     60

aaagttttct agacagactt cctgtgaaga acaaggagca gggggaaagg ggaaggggta    120

gaatttacca atctgaatat ttcagcaagg gagaatgcat gagttttact ataaaaccac    180

actgaacatt gcaacaatac taaattccat acatatataa taatcactga gctataaggt    240

tgctgatgta tttgttcttg aaagtgaatt agagttactt tatgcagaat cagctagttt    300

tatgtttcat aatgtctttc ccttttttga actttttttt aagtctaaag tagggggaac    360

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    420

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    480

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    540

catgaatttc taccagatgt gcttttattt agctttacat attcttatga aaaccaaatt    600

ttaaaagcca caggtgttga ttgttataaa ataacatgct gccattcttg attgctagag    660

tttttgttag tactttggat gcaattaaaa ctatgtgcta tcacatgtga aaagcttaat    720

aaattccatc tatcagtagt ataggtctca atatttatta tgagaccagt ggtctggaaa    780

cagcttgttg taccgaatca actggagtct atgcttaaaa aaaaaaaatt tttttttaac    840

catccttaaa ttattgctta atggtatcat attaacatat tctaaataag ggctttaagg    900

cacaggctgt tgaagcattt tctcagagga gtggatctgt agaagtctgt ctttctatag    960

aaatattgtg cttactcaag tgttaaatta ttttttctat gaactagtct acttcttaaa   1020

attcaaacat attcttttga tcacattgtt tcttgagcat cctgccctgc tactaacttt   1080

tcaacaaggc aaaatggagt aaagtggcaa tttctttaga tgagtgaaat accctcaagt   1140

ctcttttctg cccaaaaagg gaaaagtgat agaaatgggg gtggcaagtg gggtgagtgg   1200

atgaaggtgg gtattggggg tggctgtgaa agaaaataat ggagaatcac ttttctagac   1260

atctacctat acttaatcta agaaacaaag taatctactg taaagtactc tgccccttga   1320

aagaagtatt aaaaagagtg aggatggatt tagaaaaaaa catgaattta gaaatattca   1380

aaatggtttt tgtggcagat tcaatattat gaattcacag atatttaaag aatgagaaac   1440

atagtaatta gtagaaatgc cagaaacagt tcctggttcc tcttgtgttt gacactaaga   1500

aaatagcaag agtgtgaaat ctcagatact tatgaaatct cacagatgta aggactcaag   1560

tgtagaagaa aatatcccct tcttacaaaa agaaatgtca atttatggag tttgtgggaa   1620

atagggcaag aattcttatg cttatgagag ccaagtagtc agtggaagag agtagagctc   1680

aaaactggat tatcacctta gcaacttaga atagtttgaa atagaaaaaa agtatttaat   1740

ttggatctgg atctgttaag atatgcacag tctatttttt gtatagtatt ggaaaataaa   1800

aatgctataa tttgggtatg ggttcttttg tatacattac ctgcccattg aggaaagggg   1860

caagtccatt atgcaacttc tctccaaacc cttcatattc tggatatgat acttaaagag   1920

ccatgagcag ctacattctg cctatcagaa ggcatttatt aaatgactgc ttgctgaaga   1980

tgtgtccaaa gagatcctac attaaggtca tttgtcagaa tgatgtttgt gtttgtttag   2040

agttggctga cctccaactc ctggggtcaa ggaatcctac tgccttagct tcccaaatag   2100

ctaggactat aggcatgcac ccggccatgt gttttattta tagctcttaa agcccagatg   2160

aagaaatcac atttttgccc atagtgaaga aacatttggc cattgattag tccttatttt   2220

cagtgactgt cctgttttca ttagattaga gagaccctgt gtgggccaca gttaatataa   2280

accattatca cttttaagta aacctgcaca tcttagattt cataatttcc ttattgttct   2340

gactcaaaat gaactaagag cttttcactt tttgtttgta agttctcaga gagtcgggtc   2400

tgcaagtgct tttgcctgcc aggattttgt actcaaataa atgctatttg gcaactaaaa   2460

ttcttgccag ctctcatgta attttgatgt tactgaggtt ggttggtagt ttattttatt   2520

aattttgtgg ttcttctatc atatagaaaa agccaaatac agttttgttt gaatatttgt   2580


<210>  5804
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  5804

Met His Cys His Glu Phe Leu Pro Asp Val Leu Leu Phe Ser Phe Thr 
1               5                   10                  15


Tyr Ser Tyr Glu Asn Gln Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr 
            20                  25                  30


Lys Ile Thr Cys Cys His Ser 
        35


<210>  5805
<211>  3777
<212>  DNA
<213>  Homo sapiens

<400>  5805
attacttatg tctgagactg gccctgttca tggaatcaaa tgcatactct taaaatatta     60

gatcagaaat tgagaatctt acattataaa tacttgtatg tacctgcaca tatatggtac    120

agattatatc tgttcttttg ccgattgaga ataatgttga agaggaatca attatatttt    180

caaactagtt ggattttttt tcagtatttg tatttactat ttgtttttct tttctctcca    240

tagaaactcc ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg    300

gggaaccaag cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag    360

tgccaccacc acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct    420

ttgttctgct acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg    480

cattgccatg aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa    540

atagtttgtg ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt    600

tagtgtacat ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat    660

ggggacattc actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt    720

acaaaattgc tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt    780

ttttcccctc tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat    840

tctgaatcct ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac    900

tagctacaaa aaatattttg gaataagcat tgttttggta taaggtacat attttggttg    960

aagacaccag actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca   1020

atatgtaatc aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac   1080

cgtttgtgac agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt   1140

ttcaccaggt taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg   1200

ttcagtaggt tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta   1260

gatctagaag ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc   1320

acttaatcca tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt   1380

gaaaattttt tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa   1440

atcaactcat cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag   1500

aacctgtctc ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca   1560

tatttgcata gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt   1620

ttccttatac tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg   1680

attgttttat tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat   1740

tttttaaaag catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta   1800

aaagccacag gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt   1860

ttgttagtac tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa   1920

ttccatctat cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag   1980

cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat   2040

ccttaaatta ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac   2100

aggctgttga agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa   2160

tattgtgctt actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt   2220

caaacatatt cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca   2280

acaaggcaaa atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc   2340

ttttctgccc aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg   2400

aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc   2460

tacctatact taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag   2520

aagtattaaa aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa   2580

tggtttttgt ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata   2640

gtaattagta gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa   2700

tagcaagagt gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt   2760

agaagaaaat atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata   2820

gggcaagaat tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa   2880

actggattat caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg   2940

gatctggatc tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat   3000

gctataattt gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa   3060

gtccattatg caacttctct ccaaaccctt catattctgg atatgatact taaagagcca   3120

tgagcagcta cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt   3180

gtccaaagag atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt   3240

tggctgacct ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta   3300

ggactatagg catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag   3360

aaatcacatt tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag   3420

tgactgtcct gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc   3480

attatcactt ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac   3540

tcaaaatgaa ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc   3600

aagtgctttt gcctgccagg attttgtact caaataaatg ctatttggca actaaaattc   3660

ttgccagctc tcatgtaatt ttgatgttac tgaggttggt tggtagttta ttttattaat   3720

tttgtggttc ttctatcata tagaaaaagc caaatacagt tttgtttgaa tatttgt      3777


<210>  5806
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5806

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5807
<211>  3711
<212>  DNA
<213>  Homo sapiens

<400>  5807
actccttcaa accagtacct ggaaggctca tctaaggtct tctaggccta gcattctaac     60

atcaaatgat catctgatga tcatttaagg ttgttgaaaa attctggttg tgaacttctt    120

tgtcttttta gttcttcatg atcatgcagg attgcaagcc ttttcacatt cctttagaaa    180

ctccccaact tttaaatcat ttgaagaaaa ggtcgaaaac ttaaaggcaa tagggggaac    240

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    300

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    360

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    420

catgaatttc taccagatgt gcttttattt agctttacat attcctttga ccaaatagtt    480

tgtgggttaa acaaaatgaa aatatcttca cctctattct tgggaaacac cctttagtgt    540

acatttatgt tcctttattt aggaaacacc attataaaaa cacttatagt aaatggggac    600

attcactata atgatctaag aagctacaga ttgtcatagt tgttttcctg ctttacaaaa    660

ttgctccaga tctggaatgc cagtttgacc tttgtcttct ataatatttc ctttttttcc    720

cctctttgaa tctctgtata tttgattctt aactaaaatt gttctcttaa atattctgaa    780

tcctggtaat taaaagtttg ggtgtatttt ctttacctcc aaggaaagaa ctactagcta    840

caaaaaatat tttggaataa gcattgtttt ggtataaggt acatattttg gttgaagaca    900

ccagactgaa gtaaacagct gtgcatccaa tttattatag ttttgtaagt aacaatatgt    960

aatcaaactt ctaggtgact tgagagtgga acctcctata tcattattta gcaccgtttg   1020

tgacagtaac catttcagtg tattgtttat tataccactt atatcaactt atttttcacc   1080

aggttaaaat tttaatttct acaaaataac attctgaatc aagcacactg tatgttcagt   1140

aggttgaact atgaacactg tcatcaatgt tcagttcaaa agcctgaaag tttagatcta   1200

gaagctggta aaaatgacaa tatcaatcac attaggggaa ccattgttgt cttcacttaa   1260

tccatttagc actatttaaa ataagcacac caagttatat gactaatata acttgaaaat   1320

tttttatact gaggggttgg tgataactct tgaggatgta atgcattaat aaaaatcaac   1380

tcatcatttt ctacttgttt tcaatgtgtt ggaaactgta aaatgatact gtagaacctg   1440

tctcctactt tgaaaactga atgtcagggc tgagtgaatc aaagtgtcta gacatatttg   1500

catagaggcc aaggtattct attctaataa ctgcttactc aacactacca ccttttcctt   1560

atactgtata tgattatggc ctacaatgtt gtatttgtta tttattaaat tgtgattgtt   1620

ttattattgt ttatgccaaa tgttaactgc caagcttgga gtgacctaaa gcatttttta   1680

aaagcatggc tagatttact tcagtataaa ttatcttatg aaaaccaaat tttaaaagcc   1740

acaggtgttg attgttataa aataacatgc tgccattctt gattgctaga gtttttgtta   1800

gtactttgga tgcaattaaa actatgtgct atcacatgtg aaaagcttaa taaattccat   1860

ctatcagtag tataggtctc aatatttatt atgagaccag tggtctggaa acagcttgtt   1920

gtaccgaatc aactggagtc tatgcttaaa aaaaaaaaat ttttttttaa ccatccttaa   1980

attattgctt aatggtatca tattaacata ttctaaataa gggctttaag gcacaggctg   2040

ttgaagcatt ttctcagagg agtggatctg tagaagtctg tctttctata gaaatattgt   2100

gcttactcaa gtgttaaatt attttttcta tgaactagtc tacttcttaa aattcaaaca   2160

tattcttttg atcacattgt ttcttgagca tcctgccctg ctactaactt ttcaacaagg   2220

caaaatggag taaagtggca atttctttag atgagtgaaa taccctcaag tctcttttct   2280

gcccaaaaag ggaaaagtga tagaaatggg ggtggcaagt ggggtgagtg gatgaaggtg   2340

ggtattgggg gtggctgtga aagaaaataa tggagaatca cttttctaga catctaccta   2400

tacttaatct aagaaacaaa gtaatctact gtaaagtact ctgccccttg aaagaagtat   2460

taaaaagagt gaggatggat ttagaaaaaa acatgaattt agaaatattc aaaatggttt   2520

ttgtggcaga ttcaatatta tgaattcaca gatatttaaa gaatgagaaa catagtaatt   2580

agtagaaatg ccagaaacag ttcctggttc ctcttgtgtt tgacactaag aaaatagcaa   2640

gagtgtgaaa tctcagatac ttatgaaatc tcacagatgt aaggactcaa gtgtagaaga   2700

aaatatcccc ttcttacaaa aagaaatgtc aatttatgga gtttgtggga aatagggcaa   2760

gaattcttat gcttatgaga gccaagtagt cagtggaaga gagtagagct caaaactgga   2820

ttatcacctt agcaacttag aatagtttga aatagaaaaa aagtatttaa tttggatctg   2880

gatctgttaa gatatgcaca gtctattttt tgtatagtat tggaaaataa aaatgctata   2940

atttgggtat gggttctttt gtatacatta cctgcccatt gaggaaaggg gcaagtccat   3000

tatgcaactt ctctccaaac ccttcatatt ctggatatga tacttaaaga gccatgagca   3060

gctacattct gcctatcaga aggcatttat taaatgactg cttgctgaag atgtgtccaa   3120

agagatccta cattaaggtc atttgtcaga atgatgtttg tgtttgttta gagttggctg   3180

acctccaact cctggggtca aggaatccta ctgccttagc ttcccaaata gctaggacta   3240

taggcatgca cccggccatg tgttttattt atagctctta aagcccagat gaagaaatca   3300

catttttgcc catagtgaag aaacatttgg ccattgatta gtccttattt tcagtgactg   3360

tcctgttttc attagattag agagaccctg tgtgggccac agttaatata aaccattatc   3420

acttttaagt aaacctgcac atcttagatt tcataatttc cttattgttc tgactcaaaa   3480

tgaactaaga gcttttcact ttttgtttgt aagttctcag agagtcgggt ctgcaagtgc   3540

ttttgcctgc caggattttg tactcaaata aatgctattt ggcaactaaa attcttgcca   3600

gctctcatgt aattttgatg ttactgaggt tggttggtag tttattttat taattttgtg   3660

gttcttctat catatagaaa aagccaaata cagttttgtt tgaatatttg t            3711


<210>  5808
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5808

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5809
<211>  3699
<212>  DNA
<213>  Homo sapiens

<400>  5809
agagtgaggg agggcactcc ttcaaaccag tacctggaag gctcatctaa ggtcttctag     60

gcctagcatt ctaacatcaa atgatcatct gatgatcatt taaggttgtt gaaaaattct    120

ggttgtgaac ttctttgtct ttttagttct tcatgatcat gcaggaaact ccccaacttt    180

taaatcattt gaagaaaagg tcgaaaactt aaaggcaata gggggaacca agcctgctgg    240

tggtgatttt ggagaagtct tgaattcggc tgcaaatgct agtgccacca ccacggagcc    300

tcttccagaa aagacacagg agagcctgtg agattcctac ctttgttctg ctacccactg    360

ccagatgctg caagcgaggt ccaagcacat cttgtcaaca tgcattgcca tgaatttcta    420

ccagatgtgc ttttatttag ctttacatat tcctttgacc aaatagtttg tgggttaaac    480

aaaatgaaaa tatcttcacc tctattcttg ggaaacaccc tttagtgtac atttatgttc    540

ctttatttag gaaacaccat tataaaaaca cttatagtaa atggggacat tcactataat    600

gatctaagaa gctacagatt gtcatagttg ttttcctgct ttacaaaatt gctccagatc    660

tggaatgcca gtttgacctt tgtcttctat aatatttcct ttttttcccc tctttgaatc    720

tctgtatatt tgattcttaa ctaaaattgt tctcttaaat attctgaatc ctggtaatta    780

aaagtttggg tgtattttct ttacctccaa ggaaagaact actagctaca aaaaatattt    840

tggaataagc attgttttgg tataaggtac atattttggt tgaagacacc agactgaagt    900

aaacagctgt gcatccaatt tattatagtt ttgtaagtaa caatatgtaa tcaaacttct    960

aggtgacttg agagtggaac ctcctatatc attatttagc accgtttgtg acagtaacca   1020

tttcagtgta ttgtttatta taccacttat atcaacttat ttttcaccag gttaaaattt   1080

taatttctac aaaataacat tctgaatcaa gcacactgta tgttcagtag gttgaactat   1140

gaacactgtc atcaatgttc agttcaaaag cctgaaagtt tagatctaga agctggtaaa   1200

aatgacaata tcaatcacat taggggaacc attgttgtct tcacttaatc catttagcac   1260

tatttaaaat aagcacacca agttatatga ctaatataac ttgaaaattt tttatactga   1320

ggggttggtg ataactcttg aggatgtaat gcattaataa aaatcaactc atcattttct   1380

acttgttttc aatgtgttgg aaactgtaaa atgatactgt agaacctgtc tcctactttg   1440

aaaactgaat gtcagggctg agtgaatcaa agtgtctaga catatttgca tagaggccaa   1500

ggtattctat tctaataact gcttactcaa cactaccacc ttttccttat actgtatatg   1560

attatggcct acaatgttgt atttgttatt tattaaattg tgattgtttt attattgttt   1620

atgccaaatg ttaactgcca agcttggagt gacctaaagc attttttaaa agcatggcta   1680

gatttacttc agtataaatt atcttatgaa aaccaaattt taaaagccac aggtgttgat   1740

tgttataaaa taacatgctg ccattcttga ttgctagagt ttttgttagt actttggatg   1800

caattaaaac tatgtgctat cacatgtgaa aagcttaata aattccatct atcagtagta   1860

taggtctcaa tatttattat gagaccagtg gtctggaaac agcttgttgt accgaatcaa   1920

ctggagtcta tgcttaaaaa aaaaaaattt ttttttaacc atccttaaat tattgcttaa   1980

tggtatcata ttaacatatt ctaaataagg gctttaaggc acaggctgtt gaagcatttt   2040

ctcagaggag tggatctgta gaagtctgtc tttctataga aatattgtgc ttactcaagt   2100

gttaaattat tttttctatg aactagtcta cttcttaaaa ttcaaacata ttcttttgat   2160

cacattgttt cttgagcatc ctgccctgct actaactttt caacaaggca aaatggagta   2220

aagtggcaat ttctttagat gagtgaaata ccctcaagtc tcttttctgc ccaaaaaggg   2280

aaaagtgata gaaatggggg tggcaagtgg ggtgagtgga tgaaggtggg tattgggggt   2340

ggctgtgaaa gaaaataatg gagaatcact tttctagaca tctacctata cttaatctaa   2400

gaaacaaagt aatctactgt aaagtactct gccccttgaa agaagtatta aaaagagtga   2460

ggatggattt agaaaaaaac atgaatttag aaatattcaa aatggttttt gtggcagatt   2520

caatattatg aattcacaga tatttaaaga atgagaaaca tagtaattag tagaaatgcc   2580

agaaacagtt cctggttcct cttgtgtttg acactaagaa aatagcaaga gtgtgaaatc   2640

tcagatactt atgaaatctc acagatgtaa ggactcaagt gtagaagaaa atatcccctt   2700

cttacaaaaa gaaatgtcaa tttatggagt ttgtgggaaa tagggcaaga attcttatgc   2760

ttatgagagc caagtagtca gtggaagaga gtagagctca aaactggatt atcaccttag   2820

caacttagaa tagtttgaaa tagaaaaaaa gtatttaatt tggatctgga tctgttaaga   2880

tatgcacagt ctattttttg tatagtattg gaaaataaaa atgctataat ttgggtatgg   2940

gttcttttgt atacattacc tgcccattga ggaaaggggc aagtccatta tgcaacttct   3000

ctccaaaccc ttcatattct ggatatgata cttaaagagc catgagcagc tacattctgc   3060

ctatcagaag gcatttatta aatgactgct tgctgaagat gtgtccaaag agatcctaca   3120

ttaaggtcat ttgtcagaat gatgtttgtg tttgtttaga gttggctgac ctccaactcc   3180

tggggtcaag gaatcctact gccttagctt cccaaatagc taggactata ggcatgcacc   3240

cggccatgtg ttttatttat agctcttaaa gcccagatga agaaatcaca tttttgccca   3300

tagtgaagaa acatttggcc attgattagt ccttattttc agtgactgtc ctgttttcat   3360

tagattagag agaccctgtg tgggccacag ttaatataaa ccattatcac ttttaagtaa   3420

acctgcacat cttagatttc ataatttcct tattgttctg actcaaaatg aactaagagc   3480

ttttcacttt ttgtttgtaa gttctcagag agtcgggtct gcaagtgctt ttgcctgcca   3540

ggattttgta ctcaaataaa tgctatttgg caactaaaat tcttgccagc tctcatgtaa   3600

ttttgatgtt actgaggttg gttggtagtt tattttatta attttgtggt tcttctatca   3660

tatagaaaaa gccaaataca gttttgtttg aatatttgt                          3699


<210>  5810
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5810

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5811
<211>  3867
<212>  DNA
<213>  Homo sapiens

<400>  5811
ctttctggct ggactagggc actgcagaag attgtgcctg agcttagggt tgagcatacg     60

aagatgtggt gatgccgctc tgctggttat gaaggatttt agaagttctg aaaaatgttt    120

tctctttttg agagttctcc agcaggtggt gaccactgca cttgaaacaa ttgatattag    180

aaaagatgag ctgacccttc ttttgctctg tgtgtttata atttaatata gttacaagaa    240

gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg    300

ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga    360

agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg    420

agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa    480

gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca    540

agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt    600

ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata    660

tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga    720

aacaccatta taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc    780

tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt    840

ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg    900

attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg    960

tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat   1020

tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc   1080

atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag   1140

agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt   1200

gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa   1260

aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat   1320

caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc   1380

aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa   1440

gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat   1500

aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa   1560

tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt   1620

cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc   1680

taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac   1740

aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt   1800

aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag   1860

tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata   1920

acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta   1980

tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata   2040

tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg   2100

cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt   2160

aacatattct aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg   2220

gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt   2280

tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct   2340

tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt   2400

ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga   2460

aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga   2520

aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa   2580

tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag   2640

aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa   2700

ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc   2760

tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat   2820

gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga   2880

aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca   2940

agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca acttagaata   3000

gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct   3060

attttttgta tagtattgga aaataaaaat gctataattt gggtatgggt tcttttgtat   3120

acattacctg cccattgagg aaaggggcaa gtccattatg caacttctct ccaaaccctt   3180

catattctgg atatgatact taaagagcca tgagcagcta cattctgcct atcagaaggc   3240

atttattaaa tgactgcttg ctgaagatgt gtccaaagag atcctacatt aaggtcattt   3300

gtcagaatga tgtttgtgtt tgtttagagt tggctgacct ccaactcctg gggtcaagga   3360

atcctactgc cttagcttcc caaatagcta ggactatagg catgcacccg gccatgtgtt   3420

ttatttatag ctcttaaagc ccagatgaag aaatcacatt tttgcccata gtgaagaaac   3480

atttggccat tgattagtcc ttattttcag tgactgtcct gttttcatta gattagagag   3540

accctgtgtg ggccacagtt aatataaacc attatcactt ttaagtaaac ctgcacatct   3600

tagatttcat aatttcctta ttgttctgac tcaaaatgaa ctaagagctt ttcacttttt   3660

gtttgtaagt tctcagagag tcgggtctgc aagtgctttt gcctgccagg attttgtact   3720

caaataaatg ctatttggca actaaaattc ttgccagctc tcatgtaatt ttgatgttac   3780

tgaggttggt tggtagttta ttttattaat tttgtggttc ttctatcata tagaaaaagc   3840

caaatacagt tttgtttgaa tatttgt                                       3867


<210>  5812
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5812

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5813
<211>  3965
<212>  DNA
<213>  Homo sapiens

<400>  5813
ggagcttaaa tagggatttt acttagattt tgcactttaa aaaatggttt aaatccccaa     60

ccaggtctgc tgagaacaga cccagtccct gaggaaggag aagatgttgc tgccacgatc    120

agtgccacag agaccctctc ggaagaggag caggaagagc taagaagaga acttgcaaag    180

gtagaagaag aaatccagac tctgtctcaa gtgttagcag caaaagagaa gcatctagca    240

gagatcaagc ggaaacttgg aatcaattct ctacaggaac taaaacagaa cattgccaaa    300

gggtggcaag acgtgacagc aacatctgct tacaagaaga catctgaaac cttatcccag    360

gctggacaga aggcctcagc tgctttttcg tctgttggct cagtcatcac caaaaagctg    420

gaagatgtaa aaaactcccc aacttttaaa tcatttgaag aaaaggtcga aaacttaaag    480

gcaatagggg gaaccaagcc tgctggtggt gattttggag aagtcttgaa ttcggctgca    540

aatgctagtg ccaccaccac ggagcctctt ccagaaaaga cacaggagag cctgtgagat    600

tcctaccttt gttctgctac ccactgccag atgctgcaag cgaggtccaa gcacatcttg    660

tcaacatgca ttgccatgaa tttctaccag atgtgctttt atttagcttt acatattcct    720

ttgaccaaat agtttgtggg ttaaacaaaa tgaaaatatc ttcacctcta ttcttgggaa    780

acacccttta gtgtacattt atgttccttt atttaggaaa caccattata aaaacactta    840

tagtaaatgg ggacattcac tataatgatc taagaagcta cagattgtca tagttgtttt    900

cctgctttac aaaattgctc cagatctgga atgccagttt gacctttgtc ttctataata    960

tttccttttt ttcccctctt tgaatctctg tatatttgat tcttaactaa aattgttctc   1020

ttaaatattc tgaatcctgg taattaaaag tttgggtgta ttttctttac ctccaaggaa   1080

agaactacta gctacaaaaa atattttgga ataagcattg ttttggtata aggtacatat   1140

tttggttgaa gacaccagac tgaagtaaac agctgtgcat ccaatttatt atagttttgt   1200

aagtaacaat atgtaatcaa acttctaggt gacttgagag tggaacctcc tatatcatta   1260

tttagcaccg tttgtgacag taaccatttc agtgtattgt ttattatacc acttatatca   1320

acttattttt caccaggtta aaattttaat ttctacaaaa taacattctg aatcaagcac   1380

actgtatgtt cagtaggttg aactatgaac actgtcatca atgttcagtt caaaagcctg   1440

aaagtttaga tctagaagct ggtaaaaatg acaatatcaa tcacattagg ggaaccattg   1500

ttgtcttcac ttaatccatt tagcactatt taaaataagc acaccaagtt atatgactaa   1560

tataacttga aaatttttta tactgagggg ttggtgataa ctcttgagga tgtaatgcat   1620

taataaaaat caactcatca ttttctactt gttttcaatg tgttggaaac tgtaaaatga   1680

tactgtagaa cctgtctcct actttgaaaa ctgaatgtca gggctgagtg aatcaaagtg   1740

tctagacata tttgcataga ggccaaggta ttctattcta ataactgctt actcaacact   1800

accacctttt ccttatactg tatatgatta tggcctacaa tgttgtattt gttatttatt   1860

aaattgtgat tgttttatta ttgtttatgc caaatgttaa ctgccaagct tggagtgacc   1920

taaagcattt tttaaaagca tggctagatt tacttcagta taaattatct tatgaaaacc   1980

aaattttaaa agccacaggt gttgattgtt ataaaataac atgctgccat tcttgattgc   2040

tagagttttt gttagtactt tggatgcaat taaaactatg tgctatcaca tgtgaaaagc   2100

ttaataaatt ccatctatca gtagtatagg tctcaatatt tattatgaga ccagtggtct   2160

ggaaacagct tgttgtaccg aatcaactgg agtctatgct taaaaaaaaa aaattttttt   2220

ttaaccatcc ttaaattatt gcttaatggt atcatattaa catattctaa ataagggctt   2280

taaggcacag gctgttgaag cattttctca gaggagtgga tctgtagaag tctgtctttc   2340

tatagaaata ttgtgcttac tcaagtgtta aattattttt tctatgaact agtctacttc   2400

ttaaaattca aacatattct tttgatcaca ttgtttcttg agcatcctgc cctgctacta   2460

acttttcaac aaggcaaaat ggagtaaagt ggcaatttct ttagatgagt gaaataccct   2520

caagtctctt ttctgcccaa aaagggaaaa gtgatagaaa tgggggtggc aagtggggtg   2580

agtggatgaa ggtgggtatt gggggtggct gtgaaagaaa ataatggaga atcacttttc   2640

tagacatcta cctatactta atctaagaaa caaagtaatc tactgtaaag tactctgccc   2700

cttgaaagaa gtattaaaaa gagtgaggat ggatttagaa aaaaacatga atttagaaat   2760

attcaaaatg gtttttgtgg cagattcaat attatgaatt cacagatatt taaagaatga   2820

gaaacatagt aattagtaga aatgccagaa acagttcctg gttcctcttg tgtttgacac   2880

taagaaaata gcaagagtgt gaaatctcag atacttatga aatctcacag atgtaaggac   2940

tcaagtgtag aagaaaatat ccccttctta caaaaagaaa tgtcaattta tggagtttgt   3000

gggaaatagg gcaagaattc ttatgcttat gagagccaag tagtcagtgg aagagagtag   3060

agctcaaaac tggattatca ccttagcaac ttagaatagt ttgaaataga aaaaaagtat   3120

ttaatttgga tctggatctg ttaagatatg cacagtctat tttttgtata gtattggaaa   3180

ataaaaatgc tataatttgg gtatgggttc ttttgtatac attacctgcc cattgaggaa   3240

aggggcaagt ccattatgca acttctctcc aaacccttca tattctggat atgatactta   3300

aagagccatg agcagctaca ttctgcctat cagaaggcat ttattaaatg actgcttgct   3360

gaagatgtgt ccaaagagat cctacattaa ggtcatttgt cagaatgatg tttgtgtttg   3420

tttagagttg gctgacctcc aactcctggg gtcaaggaat cctactgcct tagcttccca   3480

aatagctagg actataggca tgcacccggc catgtgtttt atttatagct cttaaagccc   3540

agatgaagaa atcacatttt tgcccatagt gaagaaacat ttggccattg attagtcctt   3600

attttcagtg actgtcctgt tttcattaga ttagagagac cctgtgtggg ccacagttaa   3660

tataaaccat tatcactttt aagtaaacct gcacatctta gatttcataa tttccttatt   3720

gttctgactc aaaatgaact aagagctttt cactttttgt ttgtaagttc tcagagagtc   3780

gggtctgcaa gtgcttttgc ctgccaggat tttgtactca aataaatgct atttggcaac   3840

taaaattctt gccagctctc atgtaatttt gatgttactg aggttggttg gtagtttatt   3900

ttattaattt tgtggttctt ctatcatata gaaaaagcca aatacagttt tgtttgaata   3960

tttgt                                                               3965


<210>  5814
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5814

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5815
<211>  4487
<212>  DNA
<213>  Homo sapiens

<400>  5815
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cgaggagcaa gcttctagca gcagaaaccg aactgctctg tcttctgtat tgagagccat    840

ctgcagagct gttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca    900

gctgcttttt cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc    960

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag   1020

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc   1080

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct   1140

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg   1200

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg   1260

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1320

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1380

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1440

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1500

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1560

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1620

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1680

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1740

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1800

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1860

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1920

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1980

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   2040

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   2100

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   2160

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   2220

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   2280

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2340

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2400

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2460

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2520

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2580

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2640

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2700

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2760

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2820

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2880

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2940

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   3000

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   3060

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   3120

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   3180

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   3240

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3300

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3360

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3420

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3480

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3540

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3600

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3660

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3720

gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg   3780

caacttctct ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta   3840

cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag   3900

atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct   3960

ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg   4020

catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt   4080

tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct   4140

gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt   4200

ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa   4260

ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt   4320

gcctgccagg attttgtact caaataaatg ctatttggca actaaaattc ttgccagctc   4380

tcatgtaatt ttgatgttac tgaggttggt tggtagttta ttttattaat tttgtggttc   4440

ttctatcata tagaaaaagc caaatacagt tttgtttgaa tatttgt                 4487


<210>  5816
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5816

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Arg Ser Lys Leu Leu Ala Ala Glu Thr 
    130                 135                 140


Glu Leu Leu Cys Leu Leu Tyr 
145                 150


<210>  5817
<211>  4486
<212>  DNA
<213>  Homo sapiens

<400>  5817
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaattgcaa gccttttcac    900

attcctttag tatacgttcc attcagcatt caattagcat gcctgctatg agaaactccc    960

caacttttaa atcatttgaa gaaaaggtcg aaaacttaaa ggcaataggg ggaaccaagc   1020

ctgctggtgg tgattttgga gaagtcttga attcggctgc aaatgctagt gccaccacca   1080

cggagcctct tccagaaaag acacaggaga gcctgtgaga ttcctacctt tgttctgcta   1140

cccactgcca gatgctgcaa gcgaggtcca agcacatctt gtcaacatgc attgccatga   1200

atttctacca gatgtgcttt tatttagctt tacatattcc tttgaccaaa tagtttgtgg   1260

gttaaacaaa atgaaaatat cttcacctct attcttggga aacacccttt agtgtacatt   1320

tatgttcctt tatttaggaa acaccattat aaaaacactt atagtaaatg gggacattca   1380

ctataatgat ctaagaagct acagattgtc atagttgttt tcctgcttta caaaattgct   1440

ccagatctgg aatgccagtt tgacctttgt cttctataat atttcctttt tttcccctct   1500

ttgaatctct gtatatttga ttcttaacta aaattgttct cttaaatatt ctgaatcctg   1560

gtaattaaaa gtttgggtgt attttcttta cctccaagga aagaactact agctacaaaa   1620

aatattttgg aataagcatt gttttggtat aaggtacata ttttggttga agacaccaga   1680

ctgaagtaaa cagctgtgca tccaatttat tatagttttg taagtaacaa tatgtaatca   1740

aacttctagg tgacttgaga gtggaacctc ctatatcatt atttagcacc gtttgtgaca   1800

gtaaccattt cagtgtattg tttattatac cacttatatc aacttatttt tcaccaggtt   1860

aaaattttaa tttctacaaa ataacattct gaatcaagca cactgtatgt tcagtaggtt   1920

gaactatgaa cactgtcatc aatgttcagt tcaaaagcct gaaagtttag atctagaagc   1980

tggtaaaaat gacaatatca atcacattag gggaaccatt gttgtcttca cttaatccat   2040

ttagcactat ttaaaataag cacaccaagt tatatgacta atataacttg aaaatttttt   2100

atactgaggg gttggtgata actcttgagg atgtaatgca ttaataaaaa tcaactcatc   2160

attttctact tgttttcaat gtgttggaaa ctgtaaaatg atactgtaga acctgtctcc   2220

tactttgaaa actgaatgtc agggctgagt gaatcaaagt gtctagacat atttgcatag   2280

aggccaaggt attctattct aataactgct tactcaacac taccaccttt tccttatact   2340

gtatatgatt atggcctaca atgttgtatt tgttatttat taaattgtga ttgttttatt   2400

attgtttatg ccaaatgtta actgccaagc ttggagtgac ctaaagcatt ttttaaaagc   2460

atggctagat ttacttcagt ataaattatc ttatgaaaac caaattttaa aagccacagg   2520

tgttgattgt tataaaataa catgctgcca ttcttgattg ctagagtttt tgttagtact   2580

ttggatgcaa ttaaaactat gtgctatcac atgtgaaaag cttaataaat tccatctatc   2640

agtagtatag gtctcaatat ttattatgag accagtggtc tggaaacagc ttgttgtacc   2700

gaatcaactg gagtctatgc ttaaaaaaaa aaaatttttt tttaaccatc cttaaattat   2760

tgcttaatgg tatcatatta acatattcta aataagggct ttaaggcaca ggctgttgaa   2820

gcattttctc agaggagtgg atctgtagaa gtctgtcttt ctatagaaat attgtgctta   2880

ctcaagtgtt aaattatttt ttctatgaac tagtctactt cttaaaattc aaacatattc   2940

ttttgatcac attgtttctt gagcatcctg ccctgctact aacttttcaa caaggcaaaa   3000

tggagtaaag tggcaatttc tttagatgag tgaaataccc tcaagtctct tttctgccca   3060

aaaagggaaa agtgatagaa atgggggtgg caagtggggt gagtggatga aggtgggtat   3120

tgggggtggc tgtgaaagaa aataatggag aatcactttt ctagacatct acctatactt   3180

aatctaagaa acaaagtaat ctactgtaaa gtactctgcc ccttgaaaga agtattaaaa   3240

agagtgagga tggatttaga aaaaaacatg aatttagaaa tattcaaaat ggtttttgtg   3300

gcagattcaa tattatgaat tcacagatat ttaaagaatg agaaacatag taattagtag   3360

aaatgccaga aacagttcct ggttcctctt gtgtttgaca ctaagaaaat agcaagagtg   3420

tgaaatctca gatacttatg aaatctcaca gatgtaagga ctcaagtgta gaagaaaata   3480

tccccttctt acaaaaagaa atgtcaattt atggagtttg tgggaaatag ggcaagaatt   3540

cttatgctta tgagagccaa gtagtcagtg gaagagagta gagctcaaaa ctggattatc   3600

accttagcaa cttagaatag tttgaaatag aaaaaaagta tttaatttgg atctggatct   3660

gttaagatat gcacagtcta ttttttgtat agtattggaa aataaaaatg ctataatttg   3720

ggtatgggtt cttttgtata cattacctgc ccattgagga aaggggcaag tccattatgc   3780

aacttctctc caaacccttc atattctgga tatgatactt aaagagccat gagcagctac   3840

attctgccta tcagaaggca tttattaaat gactgcttgc tgaagatgtg tccaaagaga   3900

tcctacatta aggtcatttg tcagaatgat gtttgtgttt gtttagagtt ggctgacctc   3960

caactcctgg ggtcaaggaa tcctactgcc ttagcttccc aaatagctag gactataggc   4020

atgcacccgg ccatgtgttt tatttatagc tcttaaagcc cagatgaaga aatcacattt   4080

ttgcccatag tgaagaaaca tttggccatt gattagtcct tattttcagt gactgtcctg   4140

ttttcattag attagagaga ccctgtgtgg gccacagtta atataaacca ttatcacttt   4200

taagtaaacc tgcacatctt agatttcata atttccttat tgttctgact caaaatgaac   4260

taagagcttt tcactttttg tttgtaagtt ctcagagagt cgggtctgca agtgcttttg   4320

cctgccagga ttttgtactc aaataaatgc tatttggcaa ctaaaattct tgccagctct   4380

catgtaattt tgatgttact gaggttggtt ggtagtttat tttattaatt ttgtggttct   4440

tctatcatat agaaaaagcc aaatacagtt ttgtttgaat atttgt                  4486


<210>  5818
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  5818

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Leu Gln Ala Phe Ser His Ser 
                165                 170                 175


Phe Ser Ile Arg Ser Ile Gln His Ser Ile Ser Met Pro Ala Met Arg 
            180                 185                 190


Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu Lys 
        195                 200                 205


Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val Leu 
    210                 215                 220


Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro Glu 
225                 230                 235                 240


Lys Thr Gln Glu Ser Leu 
                245


<210>  5819
<211>  4417
<212>  DNA
<213>  Homo sapiens

<400>  5819
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta    900

aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg    960

gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc   1020

ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc   1080

agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc   1140

agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa   1200

aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct   1260

ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc actataatga   1320

tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg   1380

gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc   1440

tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa   1500

agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg   1560

gaataagcat tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa   1620

acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag   1680

gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt   1740

tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta   1800

atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga   1860

acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa   1920

tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta   1980

tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg   2040

ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac   2100

ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa   2160

aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg   2220

tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat   2280

tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat   2340

gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga   2400

tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg   2460

ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca   2520

attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata   2580

ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact   2640

ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg   2700

gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga agcattttct   2760

cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt   2820

taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca   2880

cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa   2940

gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa   3000

aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg   3060

ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga   3120

aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg   3180

atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca   3240

atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag   3300

aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc   3360

agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct   3420

tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt   3480

atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca   3540

acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata   3600

tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt gggtatgggt   3660

tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg caacttctct   3720

ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta cattctgcct   3780

atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag atcctacatt   3840

aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct ccaactcctg   3900

gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg catgcacccg   3960

gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt tttgcccata   4020

gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct gttttcatta   4080

gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt ttaagtaaac   4140

ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa ctaagagctt   4200

ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt gcctgccagg   4260

attttgtact caaataaatg ctatttggca actaaaattc ttgccagctc tcatgtaatt   4320

ttgatgttac tgaggttggt tggtagttta ttttattaat tttgtggttc ttctatcata   4380

tagaaaaagc caaatacagt tttgtttgaa tatttgt                            4417


<210>  5820
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  5820

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Asn Ser Pro Thr Phe Lys Ser 
                165                 170                 175


Phe Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro 
            180                 185                 190


Ala Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser 
        195                 200                 205


Ala Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
    210                 215                 220


<210>  5821
<211>  3917
<212>  DNA
<213>  Homo sapiens

<400>  5821
gggagtcgcc ggcggaggcg aggaggagct ctgcgcggcg cggcgggcga tccgagccgg     60

gacgggctgc aggcgggggt gctgcagagg acacgaggcg gcgggctgga gacatggacc    120

gcggcgagca aggtagaaga agaaatccag actctgtctc aagtgttagc agcaaaagag    180

aagcatctag cagagatcaa gcggaaactt ggaatcaatt ctctacagga actaaaacag    240

aacattgcca aagggtggca agacgtgaca gcaacatctg cttacaagaa gacatctgaa    300

accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg ctcagtcatc    360

accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga agaaaaggtc    420

gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg agaagtcttg    480

aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa gacacaggag    540

agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca agcgaggtcc    600

aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt ttatttagct    660

ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata tcttcacctc    720

tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga aacaccatta    780

taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc tacagattgt    840

catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt ttgacctttg    900

tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg attcttaact    960

aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg tattttcttt   1020

acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat tgttttggta   1080

taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc atccaattta   1140

ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag agtggaacct   1200

cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt gtttattata   1260

ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa aataacattc   1320

tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat caatgttcag   1380

ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc aatcacatta   1440

ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa gcacaccaag   1500

ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat aactcttgag   1560

gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa tgtgttggaa   1620

actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt cagggctgag   1680

tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc taataactgc   1740

ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac aatgttgtat   1800

ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt aactgccaag   1860

cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag tataaattat   1920

cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata acatgctgcc   1980

attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta tgtgctatca   2040

catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata tttattatga   2100

gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa   2160

aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt aacatattct   2220

aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg gatctgtaga   2280

agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt tttctatgaa   2340

ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct tgagcatcct   2400

gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt ctttagatga   2460

gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga aatgggggtg   2520

gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga   2580

gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa tctactgtaa   2640

agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag aaaaaaacat   2700

gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa ttcacagata   2760

tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc tggttcctct   2820

tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat gaaatctcac   2880

agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga aatgtcaatt   2940

tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca agtagtcagt   3000

ggaagagagt agagctcaaa actggattat caccttagca acttagaata gtttgaaata   3060

gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct attttttgta   3120

tagtattgga aaataaaaat gctataattt gggtatgggt tcttttgtat acattacctg   3180

cccattgagg aaaggggcaa gtccattatg caacttctct ccaaaccctt catattctgg   3240

atatgatact taaagagcca tgagcagcta cattctgcct atcagaaggc atttattaaa   3300

tgactgcttg ctgaagatgt gtccaaagag atcctacatt aaggtcattt gtcagaatga   3360

tgtttgtgtt tgtttagagt tggctgacct ccaactcctg gggtcaagga atcctactgc   3420

cttagcttcc caaatagcta ggactatagg catgcacccg gccatgtgtt ttatttatag   3480

ctcttaaagc ccagatgaag aaatcacatt tttgcccata gtgaagaaac atttggccat   3540

tgattagtcc ttattttcag tgactgtcct gttttcatta gattagagag accctgtgtg   3600

ggccacagtt aatataaacc attatcactt ttaagtaaac ctgcacatct tagatttcat   3660

aatttcctta ttgttctgac tcaaaatgaa ctaagagctt ttcacttttt gtttgtaagt   3720

tctcagagag tcgggtctgc aagtgctttt gcctgccagg attttgtact caaataaatg   3780

ctatttggca actaaaattc ttgccagctc tcatgtaatt ttgatgttac tgaggttggt   3840

tggtagttta ttttattaat tttgtggttc ttctatcata tagaaaaagc caaatacagt   3900

tttgtttgaa tatttgt                                                  3917


<210>  5822
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  5822

Met Asp Arg Gly Glu Gln Gly Arg Arg Arg Asn Pro Asp Ser Val Ser 
1               5                   10                  15


Ser Val Ser Ser Lys Arg Glu Ala Ser Ser Arg Asp Gln Ala Glu Thr 
            20                  25                  30


Trp Asn Gln Phe Ser Thr Gly Thr Lys Thr Glu His Cys Gln Arg Val 
        35                  40                  45


Ala Arg Arg Asp Ser Asn Ile Cys Leu Gln Glu Asp Ile 
    50                  55                  60


<210>  5823
<211>  4042
<212>  DNA
<213>  Homo sapiens

<400>  5823
ggacttcgcg ggagtcgccg gcggaggcga ggaggagctc tgcgcggcgc ggcgggcgat     60

ccgagccggg acgggctgca ggcgggggtg ctgcagagga cacgaggcgg cgggctggag    120

acatggaccg cggcgagcaa ggtctgctga gaacagaccc agtccctgag gaaggagaag    180

atgttgctgc cacgatcagt gccacagaga ccctctcgga agaggagcag gaagagctaa    240

gaagagaact tgcaaaggta gaagaagaaa tccagactct gtctcaagtg ttagcagcaa    300

aagagaagca tctagcagag atcaagcgga aacttggaat caattctcta caggaactaa    360

aacagaacat tgccaaaggg tggcaagacg tgacagcaac atctgcttac aagaagacat    420

ctgaaacctt atcccaggct ggacagaagg cctcagctgc tttttcgtct gttggctcag    480

tcatcaccaa aaagctggaa gatgtaaaaa actccccaac ttttaaatca tttgaagaaa    540

aggtcgaaaa cttaaaggca atagggggaa ccaagcctgc tggtggtgat tttggagaag    600

tcttgaattc ggctgcaaat gctagtgcca ccaccacgga gcctcttcca gaaaagacac    660

aggagagcct gtgagattcc tacctttgtt ctgctaccca ctgccagatg ctgcaagcga    720

ggtccaagca catcttgtca acatgcattg ccatgaattt ctaccagatg tgcttttatt    780

tagctttaca tattcctttg accaaatagt ttgtgggtta aacaaaatga aaatatcttc    840

acctctattc ttgggaaaca ccctttagtg tacatttatg ttcctttatt taggaaacac    900

cattataaaa acacttatag taaatgggga cattcactat aatgatctaa gaagctacag    960

attgtcatag ttgttttcct gctttacaaa attgctccag atctggaatg ccagtttgac   1020

ctttgtcttc tataatattt cctttttttc ccctctttga atctctgtat atttgattct   1080

taactaaaat tgttctctta aatattctga atcctggtaa ttaaaagttt gggtgtattt   1140

tctttacctc caaggaaaga actactagct acaaaaaata ttttggaata agcattgttt   1200

tggtataagg tacatatttt ggttgaagac accagactga agtaaacagc tgtgcatcca   1260

atttattata gttttgtaag taacaatatg taatcaaact tctaggtgac ttgagagtgg   1320

aacctcctat atcattattt agcaccgttt gtgacagtaa ccatttcagt gtattgttta   1380

ttataccact tatatcaact tatttttcac caggttaaaa ttttaatttc tacaaaataa   1440

cattctgaat caagcacact gtatgttcag taggttgaac tatgaacact gtcatcaatg   1500

ttcagttcaa aagcctgaaa gtttagatct agaagctggt aaaaatgaca atatcaatca   1560

cattagggga accattgttg tcttcactta atccatttag cactatttaa aataagcaca   1620

ccaagttata tgactaatat aacttgaaaa ttttttatac tgaggggttg gtgataactc   1680

ttgaggatgt aatgcattaa taaaaatcaa ctcatcattt tctacttgtt ttcaatgtgt   1740

tggaaactgt aaaatgatac tgtagaacct gtctcctact ttgaaaactg aatgtcaggg   1800

ctgagtgaat caaagtgtct agacatattt gcatagaggc caaggtattc tattctaata   1860

actgcttact caacactacc accttttcct tatactgtat atgattatgg cctacaatgt   1920

tgtatttgtt atttattaaa ttgtgattgt tttattattg tttatgccaa atgttaactg   1980

ccaagcttgg agtgacctaa agcatttttt aaaagcatgg ctagatttac ttcagtataa   2040

attatcttat gaaaaccaaa ttttaaaagc cacaggtgtt gattgttata aaataacatg   2100

ctgccattct tgattgctag agtttttgtt agtactttgg atgcaattaa aactatgtgc   2160

tatcacatgt gaaaagctta ataaattcca tctatcagta gtataggtct caatatttat   2220

tatgagacca gtggtctgga aacagcttgt tgtaccgaat caactggagt ctatgcttaa   2280

aaaaaaaaaa ttttttttta accatcctta aattattgct taatggtatc atattaacat   2340

attctaaata agggctttaa ggcacaggct gttgaagcat tttctcagag gagtggatct   2400

gtagaagtct gtctttctat agaaatattg tgcttactca agtgttaaat tattttttct   2460

atgaactagt ctacttctta aaattcaaac atattctttt gatcacattg tttcttgagc   2520

atcctgccct gctactaact tttcaacaag gcaaaatgga gtaaagtggc aatttcttta   2580

gatgagtgaa ataccctcaa gtctcttttc tgcccaaaaa gggaaaagtg atagaaatgg   2640

gggtggcaag tggggtgagt ggatgaaggt gggtattggg ggtggctgtg aaagaaaata   2700

atggagaatc acttttctag acatctacct atacttaatc taagaaacaa agtaatctac   2760

tgtaaagtac tctgcccctt gaaagaagta ttaaaaagag tgaggatgga tttagaaaaa   2820

aacatgaatt tagaaatatt caaaatggtt tttgtggcag attcaatatt atgaattcac   2880

agatatttaa agaatgagaa acatagtaat tagtagaaat gccagaaaca gttcctggtt   2940

cctcttgtgt ttgacactaa gaaaatagca agagtgtgaa atctcagata cttatgaaat   3000

ctcacagatg taaggactca agtgtagaag aaaatatccc cttcttacaa aaagaaatgt   3060

caatttatgg agtttgtggg aaatagggca agaattctta tgcttatgag agccaagtag   3120

tcagtggaag agagtagagc tcaaaactgg attatcacct tagcaactta gaatagtttg   3180

aaatagaaaa aaagtattta atttggatct ggatctgtta agatatgcac agtctatttt   3240

ttgtatagta ttggaaaata aaaatgctat aatttgggta tgggttcttt tgtatacatt   3300

acctgcccat tgaggaaagg ggcaagtcca ttatgcaact tctctccaaa cccttcatat   3360

tctggatatg atacttaaag agccatgagc agctacattc tgcctatcag aaggcattta   3420

ttaaatgact gcttgctgaa gatgtgtcca aagagatcct acattaaggt catttgtcag   3480

aatgatgttt gtgtttgttt agagttggct gacctccaac tcctggggtc aaggaatcct   3540

actgccttag cttcccaaat agctaggact ataggcatgc acccggccat gtgttttatt   3600

tatagctctt aaagcccaga tgaagaaatc acatttttgc ccatagtgaa gaaacatttg   3660

gccattgatt agtccttatt ttcagtgact gtcctgtttt cattagatta gagagaccct   3720

gtgtgggcca cagttaatat aaaccattat cacttttaag taaacctgca catcttagat   3780

ttcataattt ccttattgtt ctgactcaaa atgaactaag agcttttcac tttttgtttg   3840

taagttctca gagagtcggg tctgcaagtg cttttgcctg ccaggatttt gtactcaaat   3900

aaatgctatt tggcaactaa aattcttgcc agctctcatg taattttgat gttactgagg   3960

ttggttggta gtttatttta ttaattttgt ggttcttcta tcatatagaa aaagccaaat   4020

acagttttgt ttgaatattt gt                                            4042


<210>  5824
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  5824

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu 
    130                 135                 140


Lys Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val 
145                 150                 155                 160


Leu Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro 
                165                 170                 175


Glu Lys Thr Gln Glu Ser Leu 
            180


<210>  5825
<211>  4187
<212>  DNA
<213>  Homo sapiens

<400>  5825
ggttgggtga cgccccagga aagcgctcca ggccgagggc gggcggcgcc gccgcgcccg     60

acgcctctgg gggtggggac ttcgcgggag tcgccggcgg aggcgaggag gagctctgcg    120

cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg ggggtgctgc agaggacacg    180

aggcggcggg ctggagacat ggaccgcggc gagcaaggtc tgctgagaac agacccagtc    240

cctgaggaag gagaagatgt tgctgccacg atcagtgcca cagagaccct ctcggaagag    300

gagcaggaag agctaagaag agaacttgca aaggtagaag aagaaatcca gactctgtct    360

caagtgttag cagcaaaaga gaagcatcta gcagagatca agcggaaact tggaatcaat    420

tctctacagg aactaaaaca gaacattgcc aaagggtggc aagacgtgac agcaacatct    480

gcttacaaga agacatctga aaccttatcc caggctggac agaaggcctc agctgctttt    540

tcgtctgttg gctcagtcat caccaaaaag ctggaagatg taaaattgca agccttttca    600

cattccttta gtatacgttc cattcagcat tcaattagca tgcctgctat gagaaactcc    660

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag    720

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc    780

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct    840

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg    900

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg    960

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1020

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1080

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1140

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1200

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1260

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1320

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1380

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1440

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1500

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1560

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1620

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1680

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   1740

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   1800

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   1860

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   1920

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   1980

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2040

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2100

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2160

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2220

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2280

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2340

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2400

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2460

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2520

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2580

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2640

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   2700

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   2760

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   2820

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   2880

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   2940

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3000

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3060

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3120

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3180

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3240

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3300

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3360

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3420

gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg   3480

caacttctct ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta   3540

cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag   3600

atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct   3660

ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg   3720

catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt   3780

tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct   3840

gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt   3900

ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa   3960

ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt   4020

gcctgccagg attttgtact caaataaatg ctatttggca actaaaattc ttgccagctc   4080

tcatgtaatt ttgatgttac tgaggttggt tggtagttta ttttattaat tttgtggttc   4140

ttctatcata tagaaaaagc caaatacagt tttgtttgaa tatttgt                 4187


<210>  5826
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  5826

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Leu Gln Ala Phe Ser His Ser Phe Ser Ile Arg Ser Ile Gln His 
    130                 135                 140


Ser Ile Ser Met Pro Ala Met Arg Asn Ser Pro Thr Phe Lys Ser Phe 
145                 150                 155                 160


Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro Ala 
                165                 170                 175


Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser Ala 
            180                 185                 190


Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
        195                 200                 205


<210>  5827
<211>  2456
<212>  DNA
<213>  Homo sapiens

<400>  5827
aatgttatgc aagtgtagag acagacagtt cactaggtac tttaaaataa tagaccttac     60

aaagttttct agacagactt cctgtgaaga acaaggagca gggggaaagg ggaaggggta    120

gaatttacca atctgaatat ttcagcaagg gagaatgcat gagttttact ataaaaccac    180

actgaacatt gcaacaatac taaattccat acatatataa taatcactga gctataaggt    240

tgctgatgta tttgttcttg aaagtgaatt agagttactt tatgcagaat cagctagttt    300

tatgtttcat aatgtctttc ccttttttga actttttttt aagtctaaag tagggggaac    360

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    420

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    480

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    540

catgaatttc taccagatgt gcttttattt agctttacat attcttatga aaaccaaatt    600

ttaaaagcca caggtgttga ttgttataaa ataacatgct gccattcttg attgctagag    660

tttttgttag tactttggat gcaattaaaa ctatgtgcta tcacatgtga aaagcttaat    720

aaattccatc tatcagtagt ataggtctca atatttatta tgagaccagt ggtctggaaa    780

cagcttgttg taccgaatca actggagtct atgcttaaaa aaaaaaaatt tttttttaac    840

catccttaaa ttattgctta atggtatcat attaacatat tctaaataag ggctttaagg    900

cacaggctgt tgaagcattt tctcagagga gtggatctgt agaagtctgt ctttctatag    960

aaatattgtg cttactcaag tgttaaatta ttttttctat gaactagtct acttcttaaa   1020

attcaaacat attcttttga tcacattgtt tcttgagcat cctgccctgc tactaacttt   1080

tcaacaaggc aaaatggagt aaagtggcaa tttctttaga tgagtgaaat accctcaagt   1140

ctcttttctg cccaaaaagg gaaaagtgat agaaatgggg gtggcaagtg gggtgagtgg   1200

atgaaggtgg gtattggggg tggctgtgaa agaaaataat ggagaatcac ttttctagac   1260

atctacctat acttaatcta agaaacaaag taatctactg taaagtactc tgccccttga   1320

aagaagtatt aaaaagagtg aggatggatt tagaaaaaaa catgaattta gaaatattca   1380

aaatggtttt tgtggcagat tcaatattat gaattcacag atatttaaag aatgagaaac   1440

atagtaatta gtagaaatgc cagaaacagt tcctggttcc tcttgtgttt gacactaaga   1500

aaatagcaag agtgtgaaat ctcagatact tatgaaatct cacagatgta aggactcaag   1560

tgtagaagaa aatatcccct tcttacaaaa agaaatgtca atttatggag tttgtgggaa   1620

atagggcaag aattcttatg cttatgagag ccaagtagtc agtggaagag agtagagctc   1680

aaaactggat tatcacctta gcaacttaga atagtttgaa atagaaaaaa agtatttaat   1740

ttggatctgg atctgttaag atatgcacag tctatttttt gtatagtatt ggaaaataaa   1800

aatgctataa tttgggtatg ggttcttttg tatacattac ctgcccattg aggaaagggg   1860

caagtccatt atgcaacttc tctccaaacc cttcatattc tggatatgat acttaaagag   1920

ccatgagcag ctacattctg cctatcagaa ggcatttatt aaatgactgc ttgctgaaga   1980

tgtgtccaaa gagatcctac attaaggtca tttgtcagaa tgatgtttgt gtttgtttag   2040

agttggctga cctccaactc ctggggtcaa ggaatcctac tgccttagct tcccaaatag   2100

ctaggactat aggcatgcac ccggccatgt gttttattta tagctcttaa agcccagatg   2160

aagaaatcac atttttgccc atagtgaaga aacatttggc cattgattag tccttatttt   2220

cagtgactgt cctgttttca ttagattaga gagaccctgt gtgggccaca gttaatataa   2280

accattatca cttttaagta aacctgcaca tcttagattt cataatttcc ttattgttct   2340

gactcaaaat gaactaagag cttttcactt tttgtttgta agttctcaga gagtcgggtc   2400

tgcaagtgct tttgcctgcc aggattttgt actcaaataa atgctatttg gcaact       2456


<210>  5828
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  5828

Met His Cys His Glu Phe Leu Pro Asp Val Leu Leu Phe Ser Phe Thr 
1               5                   10                  15


Tyr Ser Tyr Glu Asn Gln Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr 
            20                  25                  30


Lys Ile Thr Cys Cys His Ser 
        35


<210>  5829
<211>  3653
<212>  DNA
<213>  Homo sapiens

<400>  5829
attacttatg tctgagactg gccctgttca tggaatcaaa tgcatactct taaaatatta     60

gatcagaaat tgagaatctt acattataaa tacttgtatg tacctgcaca tatatggtac    120

agattatatc tgttcttttg ccgattgaga ataatgttga agaggaatca attatatttt    180

caaactagtt ggattttttt tcagtatttg tatttactat ttgtttttct tttctctcca    240

tagaaactcc ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg    300

gggaaccaag cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag    360

tgccaccacc acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct    420

ttgttctgct acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg    480

cattgccatg aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa    540

atagtttgtg ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt    600

tagtgtacat ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat    660

ggggacattc actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt    720

acaaaattgc tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt    780

ttttcccctc tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat    840

tctgaatcct ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac    900

tagctacaaa aaatattttg gaataagcat tgttttggta taaggtacat attttggttg    960

aagacaccag actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca   1020

atatgtaatc aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac   1080

cgtttgtgac agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt   1140

ttcaccaggt taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg   1200

ttcagtaggt tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta   1260

gatctagaag ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc   1320

acttaatcca tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt   1380

gaaaattttt tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa   1440

atcaactcat cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag   1500

aacctgtctc ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca   1560

tatttgcata gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt   1620

ttccttatac tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg   1680

attgttttat tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat   1740

tttttaaaag catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta   1800

aaagccacag gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt   1860

ttgttagtac tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa   1920

ttccatctat cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag   1980

cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat   2040

ccttaaatta ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac   2100

aggctgttga agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa   2160

tattgtgctt actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt   2220

caaacatatt cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca   2280

acaaggcaaa atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc   2340

ttttctgccc aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg   2400

aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc   2460

tacctatact taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag   2520

aagtattaaa aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa   2580

tggtttttgt ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata   2640

gtaattagta gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa   2700

tagcaagagt gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt   2760

agaagaaaat atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata   2820

gggcaagaat tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa   2880

actggattat caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg   2940

gatctggatc tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat   3000

gctataattt gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa   3060

gtccattatg caacttctct ccaaaccctt catattctgg atatgatact taaagagcca   3120

tgagcagcta cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt   3180

gtccaaagag atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt   3240

tggctgacct ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta   3300

ggactatagg catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag   3360

aaatcacatt tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag   3420

tgactgtcct gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc   3480

attatcactt ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac   3540

tcaaaatgaa ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc   3600

aagtgctttt gcctgccagg attttgtact caaataaatg ctatttggca act          3653


<210>  5830
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5830

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5831
<211>  3587
<212>  DNA
<213>  Homo sapiens

<400>  5831
actccttcaa accagtacct ggaaggctca tctaaggtct tctaggccta gcattctaac     60

atcaaatgat catctgatga tcatttaagg ttgttgaaaa attctggttg tgaacttctt    120

tgtcttttta gttcttcatg atcatgcagg attgcaagcc ttttcacatt cctttagaaa    180

ctccccaact tttaaatcat ttgaagaaaa ggtcgaaaac ttaaaggcaa tagggggaac    240

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    300

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    360

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    420

catgaatttc taccagatgt gcttttattt agctttacat attcctttga ccaaatagtt    480

tgtgggttaa acaaaatgaa aatatcttca cctctattct tgggaaacac cctttagtgt    540

acatttatgt tcctttattt aggaaacacc attataaaaa cacttatagt aaatggggac    600

attcactata atgatctaag aagctacaga ttgtcatagt tgttttcctg ctttacaaaa    660

ttgctccaga tctggaatgc cagtttgacc tttgtcttct ataatatttc ctttttttcc    720

cctctttgaa tctctgtata tttgattctt aactaaaatt gttctcttaa atattctgaa    780

tcctggtaat taaaagtttg ggtgtatttt ctttacctcc aaggaaagaa ctactagcta    840

caaaaaatat tttggaataa gcattgtttt ggtataaggt acatattttg gttgaagaca    900

ccagactgaa gtaaacagct gtgcatccaa tttattatag ttttgtaagt aacaatatgt    960

aatcaaactt ctaggtgact tgagagtgga acctcctata tcattattta gcaccgtttg   1020

tgacagtaac catttcagtg tattgtttat tataccactt atatcaactt atttttcacc   1080

aggttaaaat tttaatttct acaaaataac attctgaatc aagcacactg tatgttcagt   1140

aggttgaact atgaacactg tcatcaatgt tcagttcaaa agcctgaaag tttagatcta   1200

gaagctggta aaaatgacaa tatcaatcac attaggggaa ccattgttgt cttcacttaa   1260

tccatttagc actatttaaa ataagcacac caagttatat gactaatata acttgaaaat   1320

tttttatact gaggggttgg tgataactct tgaggatgta atgcattaat aaaaatcaac   1380

tcatcatttt ctacttgttt tcaatgtgtt ggaaactgta aaatgatact gtagaacctg   1440

tctcctactt tgaaaactga atgtcagggc tgagtgaatc aaagtgtcta gacatatttg   1500

catagaggcc aaggtattct attctaataa ctgcttactc aacactacca ccttttcctt   1560

atactgtata tgattatggc ctacaatgtt gtatttgtta tttattaaat tgtgattgtt   1620

ttattattgt ttatgccaaa tgttaactgc caagcttgga gtgacctaaa gcatttttta   1680

aaagcatggc tagatttact tcagtataaa ttatcttatg aaaaccaaat tttaaaagcc   1740

acaggtgttg attgttataa aataacatgc tgccattctt gattgctaga gtttttgtta   1800

gtactttgga tgcaattaaa actatgtgct atcacatgtg aaaagcttaa taaattccat   1860

ctatcagtag tataggtctc aatatttatt atgagaccag tggtctggaa acagcttgtt   1920

gtaccgaatc aactggagtc tatgcttaaa aaaaaaaaat ttttttttaa ccatccttaa   1980

attattgctt aatggtatca tattaacata ttctaaataa gggctttaag gcacaggctg   2040

ttgaagcatt ttctcagagg agtggatctg tagaagtctg tctttctata gaaatattgt   2100

gcttactcaa gtgttaaatt attttttcta tgaactagtc tacttcttaa aattcaaaca   2160

tattcttttg atcacattgt ttcttgagca tcctgccctg ctactaactt ttcaacaagg   2220

caaaatggag taaagtggca atttctttag atgagtgaaa taccctcaag tctcttttct   2280

gcccaaaaag ggaaaagtga tagaaatggg ggtggcaagt ggggtgagtg gatgaaggtg   2340

ggtattgggg gtggctgtga aagaaaataa tggagaatca cttttctaga catctaccta   2400

tacttaatct aagaaacaaa gtaatctact gtaaagtact ctgccccttg aaagaagtat   2460

taaaaagagt gaggatggat ttagaaaaaa acatgaattt agaaatattc aaaatggttt   2520

ttgtggcaga ttcaatatta tgaattcaca gatatttaaa gaatgagaaa catagtaatt   2580

agtagaaatg ccagaaacag ttcctggttc ctcttgtgtt tgacactaag aaaatagcaa   2640

gagtgtgaaa tctcagatac ttatgaaatc tcacagatgt aaggactcaa gtgtagaaga   2700

aaatatcccc ttcttacaaa aagaaatgtc aatttatgga gtttgtggga aatagggcaa   2760

gaattcttat gcttatgaga gccaagtagt cagtggaaga gagtagagct caaaactgga   2820

ttatcacctt agcaacttag aatagtttga aatagaaaaa aagtatttaa tttggatctg   2880

gatctgttaa gatatgcaca gtctattttt tgtatagtat tggaaaataa aaatgctata   2940

atttgggtat gggttctttt gtatacatta cctgcccatt gaggaaaggg gcaagtccat   3000

tatgcaactt ctctccaaac ccttcatatt ctggatatga tacttaaaga gccatgagca   3060

gctacattct gcctatcaga aggcatttat taaatgactg cttgctgaag atgtgtccaa   3120

agagatccta cattaaggtc atttgtcaga atgatgtttg tgtttgttta gagttggctg   3180

acctccaact cctggggtca aggaatccta ctgccttagc ttcccaaata gctaggacta   3240

taggcatgca cccggccatg tgttttattt atagctctta aagcccagat gaagaaatca   3300

catttttgcc catagtgaag aaacatttgg ccattgatta gtccttattt tcagtgactg   3360

tcctgttttc attagattag agagaccctg tgtgggccac agttaatata aaccattatc   3420

acttttaagt aaacctgcac atcttagatt tcataatttc cttattgttc tgactcaaaa   3480

tgaactaaga gcttttcact ttttgtttgt aagttctcag agagtcgggt ctgcaagtgc   3540

ttttgcctgc caggattttg tactcaaata aatgctattt ggcaact                 3587


<210>  5832
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5832

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5833
<211>  3575
<212>  DNA
<213>  Homo sapiens

<400>  5833
agagtgaggg agggcactcc ttcaaaccag tacctggaag gctcatctaa ggtcttctag     60

gcctagcatt ctaacatcaa atgatcatct gatgatcatt taaggttgtt gaaaaattct    120

ggttgtgaac ttctttgtct ttttagttct tcatgatcat gcaggaaact ccccaacttt    180

taaatcattt gaagaaaagg tcgaaaactt aaaggcaata gggggaacca agcctgctgg    240

tggtgatttt ggagaagtct tgaattcggc tgcaaatgct agtgccacca ccacggagcc    300

tcttccagaa aagacacagg agagcctgtg agattcctac ctttgttctg ctacccactg    360

ccagatgctg caagcgaggt ccaagcacat cttgtcaaca tgcattgcca tgaatttcta    420

ccagatgtgc ttttatttag ctttacatat tcctttgacc aaatagtttg tgggttaaac    480

aaaatgaaaa tatcttcacc tctattcttg ggaaacaccc tttagtgtac atttatgttc    540

ctttatttag gaaacaccat tataaaaaca cttatagtaa atggggacat tcactataat    600

gatctaagaa gctacagatt gtcatagttg ttttcctgct ttacaaaatt gctccagatc    660

tggaatgcca gtttgacctt tgtcttctat aatatttcct ttttttcccc tctttgaatc    720

tctgtatatt tgattcttaa ctaaaattgt tctcttaaat attctgaatc ctggtaatta    780

aaagtttggg tgtattttct ttacctccaa ggaaagaact actagctaca aaaaatattt    840

tggaataagc attgttttgg tataaggtac atattttggt tgaagacacc agactgaagt    900

aaacagctgt gcatccaatt tattatagtt ttgtaagtaa caatatgtaa tcaaacttct    960

aggtgacttg agagtggaac ctcctatatc attatttagc accgtttgtg acagtaacca   1020

tttcagtgta ttgtttatta taccacttat atcaacttat ttttcaccag gttaaaattt   1080

taatttctac aaaataacat tctgaatcaa gcacactgta tgttcagtag gttgaactat   1140

gaacactgtc atcaatgttc agttcaaaag cctgaaagtt tagatctaga agctggtaaa   1200

aatgacaata tcaatcacat taggggaacc attgttgtct tcacttaatc catttagcac   1260

tatttaaaat aagcacacca agttatatga ctaatataac ttgaaaattt tttatactga   1320

ggggttggtg ataactcttg aggatgtaat gcattaataa aaatcaactc atcattttct   1380

acttgttttc aatgtgttgg aaactgtaaa atgatactgt agaacctgtc tcctactttg   1440

aaaactgaat gtcagggctg agtgaatcaa agtgtctaga catatttgca tagaggccaa   1500

ggtattctat tctaataact gcttactcaa cactaccacc ttttccttat actgtatatg   1560

attatggcct acaatgttgt atttgttatt tattaaattg tgattgtttt attattgttt   1620

atgccaaatg ttaactgcca agcttggagt gacctaaagc attttttaaa agcatggcta   1680

gatttacttc agtataaatt atcttatgaa aaccaaattt taaaagccac aggtgttgat   1740

tgttataaaa taacatgctg ccattcttga ttgctagagt ttttgttagt actttggatg   1800

caattaaaac tatgtgctat cacatgtgaa aagcttaata aattccatct atcagtagta   1860

taggtctcaa tatttattat gagaccagtg gtctggaaac agcttgttgt accgaatcaa   1920

ctggagtcta tgcttaaaaa aaaaaaattt ttttttaacc atccttaaat tattgcttaa   1980

tggtatcata ttaacatatt ctaaataagg gctttaaggc acaggctgtt gaagcatttt   2040

ctcagaggag tggatctgta gaagtctgtc tttctataga aatattgtgc ttactcaagt   2100

gttaaattat tttttctatg aactagtcta cttcttaaaa ttcaaacata ttcttttgat   2160

cacattgttt cttgagcatc ctgccctgct actaactttt caacaaggca aaatggagta   2220

aagtggcaat ttctttagat gagtgaaata ccctcaagtc tcttttctgc ccaaaaaggg   2280

aaaagtgata gaaatggggg tggcaagtgg ggtgagtgga tgaaggtggg tattgggggt   2340

ggctgtgaaa gaaaataatg gagaatcact tttctagaca tctacctata cttaatctaa   2400

gaaacaaagt aatctactgt aaagtactct gccccttgaa agaagtatta aaaagagtga   2460

ggatggattt agaaaaaaac atgaatttag aaatattcaa aatggttttt gtggcagatt   2520

caatattatg aattcacaga tatttaaaga atgagaaaca tagtaattag tagaaatgcc   2580

agaaacagtt cctggttcct cttgtgtttg acactaagaa aatagcaaga gtgtgaaatc   2640

tcagatactt atgaaatctc acagatgtaa ggactcaagt gtagaagaaa atatcccctt   2700

cttacaaaaa gaaatgtcaa tttatggagt ttgtgggaaa tagggcaaga attcttatgc   2760

ttatgagagc caagtagtca gtggaagaga gtagagctca aaactggatt atcaccttag   2820

caacttagaa tagtttgaaa tagaaaaaaa gtatttaatt tggatctgga tctgttaaga   2880

tatgcacagt ctattttttg tatagtattg gaaaataaaa atgctataat ttgggtatgg   2940

gttcttttgt atacattacc tgcccattga ggaaaggggc aagtccatta tgcaacttct   3000

ctccaaaccc ttcatattct ggatatgata cttaaagagc catgagcagc tacattctgc   3060

ctatcagaag gcatttatta aatgactgct tgctgaagat gtgtccaaag agatcctaca   3120

ttaaggtcat ttgtcagaat gatgtttgtg tttgtttaga gttggctgac ctccaactcc   3180

tggggtcaag gaatcctact gccttagctt cccaaatagc taggactata ggcatgcacc   3240

cggccatgtg ttttatttat agctcttaaa gcccagatga agaaatcaca tttttgccca   3300

tagtgaagaa acatttggcc attgattagt ccttattttc agtgactgtc ctgttttcat   3360

tagattagag agaccctgtg tgggccacag ttaatataaa ccattatcac ttttaagtaa   3420

acctgcacat cttagatttc ataatttcct tattgttctg actcaaaatg aactaagagc   3480

ttttcacttt ttgtttgtaa gttctcagag agtcgggtct gcaagtgctt ttgcctgcca   3540

ggattttgta ctcaaataaa tgctatttgg caact                              3575


<210>  5834
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5834

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5835
<211>  3743
<212>  DNA
<213>  Homo sapiens

<400>  5835
ctttctggct ggactagggc actgcagaag attgtgcctg agcttagggt tgagcatacg     60

aagatgtggt gatgccgctc tgctggttat gaaggatttt agaagttctg aaaaatgttt    120

tctctttttg agagttctcc agcaggtggt gaccactgca cttgaaacaa ttgatattag    180

aaaagatgag ctgacccttc ttttgctctg tgtgtttata atttaatata gttacaagaa    240

gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg    300

ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga    360

agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg    420

agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa    480

gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca    540

agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt    600

ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata    660

tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga    720

aacaccatta taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc    780

tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt    840

ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg    900

attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg    960

tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat   1020

tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc   1080

atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag   1140

agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt   1200

gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa   1260

aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat   1320

caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc   1380

aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa   1440

gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat   1500

aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa   1560

tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt   1620

cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc   1680

taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac   1740

aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt   1800

aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag   1860

tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata   1920

acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta   1980

tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata   2040

tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg   2100

cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt   2160

aacatattct aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg   2220

gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt   2280

tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct   2340

tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt   2400

ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga   2460

aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga   2520

aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa   2580

tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag   2640

aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa   2700

ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc   2760

tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat   2820

gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga   2880

aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca   2940

agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca acttagaata   3000

gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct   3060

attttttgta tagtattgga aaataaaaat gctataattt gggtatgggt tcttttgtat   3120

acattacctg cccattgagg aaaggggcaa gtccattatg caacttctct ccaaaccctt   3180

catattctgg atatgatact taaagagcca tgagcagcta cattctgcct atcagaaggc   3240

atttattaaa tgactgcttg ctgaagatgt gtccaaagag atcctacatt aaggtcattt   3300

gtcagaatga tgtttgtgtt tgtttagagt tggctgacct ccaactcctg gggtcaagga   3360

atcctactgc cttagcttcc caaatagcta ggactatagg catgcacccg gccatgtgtt   3420

ttatttatag ctcttaaagc ccagatgaag aaatcacatt tttgcccata gtgaagaaac   3480

atttggccat tgattagtcc ttattttcag tgactgtcct gttttcatta gattagagag   3540

accctgtgtg ggccacagtt aatataaacc attatcactt ttaagtaaac ctgcacatct   3600

tagatttcat aatttcctta ttgttctgac tcaaaatgaa ctaagagctt ttcacttttt   3660

gtttgtaagt tctcagagag tcgggtctgc aagtgctttt gcctgccagg attttgtact   3720

caaataaatg ctatttggca act                                           3743


<210>  5836
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5836

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5837
<211>  3841
<212>  DNA
<213>  Homo sapiens

<400>  5837
ggagcttaaa tagggatttt acttagattt tgcactttaa aaaatggttt aaatccccaa     60

ccaggtctgc tgagaacaga cccagtccct gaggaaggag aagatgttgc tgccacgatc    120

agtgccacag agaccctctc ggaagaggag caggaagagc taagaagaga acttgcaaag    180

gtagaagaag aaatccagac tctgtctcaa gtgttagcag caaaagagaa gcatctagca    240

gagatcaagc ggaaacttgg aatcaattct ctacaggaac taaaacagaa cattgccaaa    300

gggtggcaag acgtgacagc aacatctgct tacaagaaga catctgaaac cttatcccag    360

gctggacaga aggcctcagc tgctttttcg tctgttggct cagtcatcac caaaaagctg    420

gaagatgtaa aaaactcccc aacttttaaa tcatttgaag aaaaggtcga aaacttaaag    480

gcaatagggg gaaccaagcc tgctggtggt gattttggag aagtcttgaa ttcggctgca    540

aatgctagtg ccaccaccac ggagcctctt ccagaaaaga cacaggagag cctgtgagat    600

tcctaccttt gttctgctac ccactgccag atgctgcaag cgaggtccaa gcacatcttg    660

tcaacatgca ttgccatgaa tttctaccag atgtgctttt atttagcttt acatattcct    720

ttgaccaaat agtttgtggg ttaaacaaaa tgaaaatatc ttcacctcta ttcttgggaa    780

acacccttta gtgtacattt atgttccttt atttaggaaa caccattata aaaacactta    840

tagtaaatgg ggacattcac tataatgatc taagaagcta cagattgtca tagttgtttt    900

cctgctttac aaaattgctc cagatctgga atgccagttt gacctttgtc ttctataata    960

tttccttttt ttcccctctt tgaatctctg tatatttgat tcttaactaa aattgttctc   1020

ttaaatattc tgaatcctgg taattaaaag tttgggtgta ttttctttac ctccaaggaa   1080

agaactacta gctacaaaaa atattttgga ataagcattg ttttggtata aggtacatat   1140

tttggttgaa gacaccagac tgaagtaaac agctgtgcat ccaatttatt atagttttgt   1200

aagtaacaat atgtaatcaa acttctaggt gacttgagag tggaacctcc tatatcatta   1260

tttagcaccg tttgtgacag taaccatttc agtgtattgt ttattatacc acttatatca   1320

acttattttt caccaggtta aaattttaat ttctacaaaa taacattctg aatcaagcac   1380

actgtatgtt cagtaggttg aactatgaac actgtcatca atgttcagtt caaaagcctg   1440

aaagtttaga tctagaagct ggtaaaaatg acaatatcaa tcacattagg ggaaccattg   1500

ttgtcttcac ttaatccatt tagcactatt taaaataagc acaccaagtt atatgactaa   1560

tataacttga aaatttttta tactgagggg ttggtgataa ctcttgagga tgtaatgcat   1620

taataaaaat caactcatca ttttctactt gttttcaatg tgttggaaac tgtaaaatga   1680

tactgtagaa cctgtctcct actttgaaaa ctgaatgtca gggctgagtg aatcaaagtg   1740

tctagacata tttgcataga ggccaaggta ttctattcta ataactgctt actcaacact   1800

accacctttt ccttatactg tatatgatta tggcctacaa tgttgtattt gttatttatt   1860

aaattgtgat tgttttatta ttgtttatgc caaatgttaa ctgccaagct tggagtgacc   1920

taaagcattt tttaaaagca tggctagatt tacttcagta taaattatct tatgaaaacc   1980

aaattttaaa agccacaggt gttgattgtt ataaaataac atgctgccat tcttgattgc   2040

tagagttttt gttagtactt tggatgcaat taaaactatg tgctatcaca tgtgaaaagc   2100

ttaataaatt ccatctatca gtagtatagg tctcaatatt tattatgaga ccagtggtct   2160

ggaaacagct tgttgtaccg aatcaactgg agtctatgct taaaaaaaaa aaattttttt   2220

ttaaccatcc ttaaattatt gcttaatggt atcatattaa catattctaa ataagggctt   2280

taaggcacag gctgttgaag cattttctca gaggagtgga tctgtagaag tctgtctttc   2340

tatagaaata ttgtgcttac tcaagtgtta aattattttt tctatgaact agtctacttc   2400

ttaaaattca aacatattct tttgatcaca ttgtttcttg agcatcctgc cctgctacta   2460

acttttcaac aaggcaaaat ggagtaaagt ggcaatttct ttagatgagt gaaataccct   2520

caagtctctt ttctgcccaa aaagggaaaa gtgatagaaa tgggggtggc aagtggggtg   2580

agtggatgaa ggtgggtatt gggggtggct gtgaaagaaa ataatggaga atcacttttc   2640

tagacatcta cctatactta atctaagaaa caaagtaatc tactgtaaag tactctgccc   2700

cttgaaagaa gtattaaaaa gagtgaggat ggatttagaa aaaaacatga atttagaaat   2760

attcaaaatg gtttttgtgg cagattcaat attatgaatt cacagatatt taaagaatga   2820

gaaacatagt aattagtaga aatgccagaa acagttcctg gttcctcttg tgtttgacac   2880

taagaaaata gcaagagtgt gaaatctcag atacttatga aatctcacag atgtaaggac   2940

tcaagtgtag aagaaaatat ccccttctta caaaaagaaa tgtcaattta tggagtttgt   3000

gggaaatagg gcaagaattc ttatgcttat gagagccaag tagtcagtgg aagagagtag   3060

agctcaaaac tggattatca ccttagcaac ttagaatagt ttgaaataga aaaaaagtat   3120

ttaatttgga tctggatctg ttaagatatg cacagtctat tttttgtata gtattggaaa   3180

ataaaaatgc tataatttgg gtatgggttc ttttgtatac attacctgcc cattgaggaa   3240

aggggcaagt ccattatgca acttctctcc aaacccttca tattctggat atgatactta   3300

aagagccatg agcagctaca ttctgcctat cagaaggcat ttattaaatg actgcttgct   3360

gaagatgtgt ccaaagagat cctacattaa ggtcatttgt cagaatgatg tttgtgtttg   3420

tttagagttg gctgacctcc aactcctggg gtcaaggaat cctactgcct tagcttccca   3480

aatagctagg actataggca tgcacccggc catgtgtttt atttatagct cttaaagccc   3540

agatgaagaa atcacatttt tgcccatagt gaagaaacat ttggccattg attagtcctt   3600

attttcagtg actgtcctgt tttcattaga ttagagagac cctgtgtggg ccacagttaa   3660

tataaaccat tatcactttt aagtaaacct gcacatctta gatttcataa tttccttatt   3720

gttctgactc aaaatgaact aagagctttt cactttttgt ttgtaagttc tcagagagtc   3780

gggtctgcaa gtgcttttgc ctgccaggat tttgtactca aataaatgct atttggcaac   3840

t                                                                   3841


<210>  5838
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  5838

Met Ser Ser Tyr Ile Leu Pro Ile Arg Arg His Leu Leu Asn Asp Cys 
1               5                   10                  15


Leu Leu Lys Met Cys Pro Lys Arg Ser Tyr Ile Lys Val Ile Cys Gln 
            20                  25                  30


Asn Asp Val Cys Val Cys Leu Glu Leu Ala Asp Leu Gln Leu Leu Gly 
        35                  40                  45


Ser Arg Asn Pro Thr Ala Leu Ala Ser Gln Ile Ala Arg Thr Ile Gly 
    50                  55                  60


Met His Pro Ala Met Cys Phe Ile Tyr Ser Ser 
65                  70                  75


<210>  5839
<211>  4362
<212>  DNA
<213>  Homo sapiens

<400>  5839
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaattgcaa gccttttcac    900

attcctttag tatacgttcc attcagcatt caattagcat gcctgctatg agaaactccc    960

caacttttaa atcatttgaa gaaaaggtcg aaaacttaaa ggcaataggg ggaaccaagc   1020

ctgctggtgg tgattttgga gaagtcttga attcggctgc aaatgctagt gccaccacca   1080

cggagcctct tccagaaaag acacaggaga gcctgtgaga ttcctacctt tgttctgcta   1140

cccactgcca gatgctgcaa gcgaggtcca agcacatctt gtcaacatgc attgccatga   1200

atttctacca gatgtgcttt tatttagctt tacatattcc tttgaccaaa tagtttgtgg   1260

gttaaacaaa atgaaaatat cttcacctct attcttggga aacacccttt agtgtacatt   1320

tatgttcctt tatttaggaa acaccattat aaaaacactt atagtaaatg gggacattca   1380

ctataatgat ctaagaagct acagattgtc atagttgttt tcctgcttta caaaattgct   1440

ccagatctgg aatgccagtt tgacctttgt cttctataat atttcctttt tttcccctct   1500

ttgaatctct gtatatttga ttcttaacta aaattgttct cttaaatatt ctgaatcctg   1560

gtaattaaaa gtttgggtgt attttcttta cctccaagga aagaactact agctacaaaa   1620

aatattttgg aataagcatt gttttggtat aaggtacata ttttggttga agacaccaga   1680

ctgaagtaaa cagctgtgca tccaatttat tatagttttg taagtaacaa tatgtaatca   1740

aacttctagg tgacttgaga gtggaacctc ctatatcatt atttagcacc gtttgtgaca   1800

gtaaccattt cagtgtattg tttattatac cacttatatc aacttatttt tcaccaggtt   1860

aaaattttaa tttctacaaa ataacattct gaatcaagca cactgtatgt tcagtaggtt   1920

gaactatgaa cactgtcatc aatgttcagt tcaaaagcct gaaagtttag atctagaagc   1980

tggtaaaaat gacaatatca atcacattag gggaaccatt gttgtcttca cttaatccat   2040

ttagcactat ttaaaataag cacaccaagt tatatgacta atataacttg aaaatttttt   2100

atactgaggg gttggtgata actcttgagg atgtaatgca ttaataaaaa tcaactcatc   2160

attttctact tgttttcaat gtgttggaaa ctgtaaaatg atactgtaga acctgtctcc   2220

tactttgaaa actgaatgtc agggctgagt gaatcaaagt gtctagacat atttgcatag   2280

aggccaaggt attctattct aataactgct tactcaacac taccaccttt tccttatact   2340

gtatatgatt atggcctaca atgttgtatt tgttatttat taaattgtga ttgttttatt   2400

attgtttatg ccaaatgtta actgccaagc ttggagtgac ctaaagcatt ttttaaaagc   2460

atggctagat ttacttcagt ataaattatc ttatgaaaac caaattttaa aagccacagg   2520

tgttgattgt tataaaataa catgctgcca ttcttgattg ctagagtttt tgttagtact   2580

ttggatgcaa ttaaaactat gtgctatcac atgtgaaaag cttaataaat tccatctatc   2640

agtagtatag gtctcaatat ttattatgag accagtggtc tggaaacagc ttgttgtacc   2700

gaatcaactg gagtctatgc ttaaaaaaaa aaaatttttt tttaaccatc cttaaattat   2760

tgcttaatgg tatcatatta acatattcta aataagggct ttaaggcaca ggctgttgaa   2820

gcattttctc agaggagtgg atctgtagaa gtctgtcttt ctatagaaat attgtgctta   2880

ctcaagtgtt aaattatttt ttctatgaac tagtctactt cttaaaattc aaacatattc   2940

ttttgatcac attgtttctt gagcatcctg ccctgctact aacttttcaa caaggcaaaa   3000

tggagtaaag tggcaatttc tttagatgag tgaaataccc tcaagtctct tttctgccca   3060

aaaagggaaa agtgatagaa atgggggtgg caagtggggt gagtggatga aggtgggtat   3120

tgggggtggc tgtgaaagaa aataatggag aatcactttt ctagacatct acctatactt   3180

aatctaagaa acaaagtaat ctactgtaaa gtactctgcc ccttgaaaga agtattaaaa   3240

agagtgagga tggatttaga aaaaaacatg aatttagaaa tattcaaaat ggtttttgtg   3300

gcagattcaa tattatgaat tcacagatat ttaaagaatg agaaacatag taattagtag   3360

aaatgccaga aacagttcct ggttcctctt gtgtttgaca ctaagaaaat agcaagagtg   3420

tgaaatctca gatacttatg aaatctcaca gatgtaagga ctcaagtgta gaagaaaata   3480

tccccttctt acaaaaagaa atgtcaattt atggagtttg tgggaaatag ggcaagaatt   3540

cttatgctta tgagagccaa gtagtcagtg gaagagagta gagctcaaaa ctggattatc   3600

accttagcaa cttagaatag tttgaaatag aaaaaaagta tttaatttgg atctggatct   3660

gttaagatat gcacagtcta ttttttgtat agtattggaa aataaaaatg ctataatttg   3720

ggtatgggtt cttttgtata cattacctgc ccattgagga aaggggcaag tccattatgc   3780

aacttctctc caaacccttc atattctgga tatgatactt aaagagccat gagcagctac   3840

attctgccta tcagaaggca tttattaaat gactgcttgc tgaagatgtg tccaaagaga   3900

tcctacatta aggtcatttg tcagaatgat gtttgtgttt gtttagagtt ggctgacctc   3960

caactcctgg ggtcaaggaa tcctactgcc ttagcttccc aaatagctag gactataggc   4020

atgcacccgg ccatgtgttt tatttatagc tcttaaagcc cagatgaaga aatcacattt   4080

ttgcccatag tgaagaaaca tttggccatt gattagtcct tattttcagt gactgtcctg   4140

ttttcattag attagagaga ccctgtgtgg gccacagtta atataaacca ttatcacttt   4200

taagtaaacc tgcacatctt agatttcata atttccttat tgttctgact caaaatgaac   4260

taagagcttt tcactttttg tttgtaagtt ctcagagagt cgggtctgca agtgcttttg   4320

cctgccagga ttttgtactc aaataaatgc tatttggcaa ct                      4362


<210>  5840
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  5840

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Leu Gln Ala Phe Ser His Ser 
                165                 170                 175


Phe Ser Ile Arg Ser Ile Gln His Ser Ile Ser Met Pro Ala Met Arg 
            180                 185                 190


Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu Lys 
        195                 200                 205


Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val Leu 
    210                 215                 220


Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro Glu 
225                 230                 235                 240


Lys Thr Gln Glu Ser Leu 
                245


<210>  5841
<211>  4293
<212>  DNA
<213>  Homo sapiens

<400>  5841
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta    900

aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg    960

gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc   1020

ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc   1080

agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc   1140

agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa   1200

aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct   1260

ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc actataatga   1320

tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg   1380

gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc   1440

tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa   1500

agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg   1560

gaataagcat tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa   1620

acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag   1680

gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt   1740

tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta   1800

atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga   1860

acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa   1920

tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta   1980

tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg   2040

ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac   2100

ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa   2160

aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg   2220

tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat   2280

tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat   2340

gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga   2400

tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg   2460

ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca   2520

attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata   2580

ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact   2640

ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg   2700

gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga agcattttct   2760

cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt   2820

taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca   2880

cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa   2940

gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa   3000

aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg   3060

ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga   3120

aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg   3180

atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca   3240

atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag   3300

aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc   3360

agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct   3420

tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt   3480

atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca   3540

acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata   3600

tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt gggtatgggt   3660

tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg caacttctct   3720

ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta cattctgcct   3780

atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag atcctacatt   3840

aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct ccaactcctg   3900

gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg catgcacccg   3960

gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt tttgcccata   4020

gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct gttttcatta   4080

gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt ttaagtaaac   4140

ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa ctaagagctt   4200

ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt gcctgccagg   4260

attttgtact caaataaatg ctatttggca act                                4293


<210>  5842
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  5842

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Asn Ser Pro Thr Phe Lys Ser 
                165                 170                 175


Phe Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro 
            180                 185                 190


Ala Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser 
        195                 200                 205


Ala Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
    210                 215                 220


<210>  5843
<211>  4363
<212>  DNA
<213>  Homo sapiens

<400>  5843
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cgaggagcaa gcttctagca gcagaaaccg aactgctctg tcttctgtat tgagagccat    840

ctgcagagct gttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca    900

gctgcttttt cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc    960

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag   1020

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc   1080

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct   1140

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg   1200

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg   1260

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1320

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1380

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1440

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1500

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1560

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1620

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1680

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1740

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1800

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1860

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1920

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1980

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   2040

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   2100

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   2160

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   2220

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   2280

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2340

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2400

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2460

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2520

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2580

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2640

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2700

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2760

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2820

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2880

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2940

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   3000

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   3060

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   3120

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   3180

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   3240

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3300

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3360

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3420

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3480

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3540

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3600

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3660

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3720

gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg   3780

caacttctct ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta   3840

cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag   3900

atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct   3960

ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg   4020

catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt   4080

tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct   4140

gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt   4200

ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa   4260

ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt   4320

gcctgccagg attttgtact caaataaatg ctatttggca act                     4363


<210>  5844
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5844

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Arg Ser Lys Leu Leu Ala Ala Glu Thr 
    130                 135                 140


Glu Leu Leu Cys Leu Leu Tyr 
145                 150


<210>  5845
<211>  3793
<212>  DNA
<213>  Homo sapiens

<400>  5845
gggagtcgcc ggcggaggcg aggaggagct ctgcgcggcg cggcgggcga tccgagccgg     60

gacgggctgc aggcgggggt gctgcagagg acacgaggcg gcgggctgga gacatggacc    120

gcggcgagca aggtagaaga agaaatccag actctgtctc aagtgttagc agcaaaagag    180

aagcatctag cagagatcaa gcggaaactt ggaatcaatt ctctacagga actaaaacag    240

aacattgcca aagggtggca agacgtgaca gcaacatctg cttacaagaa gacatctgaa    300

accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg ctcagtcatc    360

accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga agaaaaggtc    420

gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg agaagtcttg    480

aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa gacacaggag    540

agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca agcgaggtcc    600

aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt ttatttagct    660

ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata tcttcacctc    720

tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga aacaccatta    780

taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc tacagattgt    840

catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt ttgacctttg    900

tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg attcttaact    960

aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg tattttcttt   1020

acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat tgttttggta   1080

taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc atccaattta   1140

ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag agtggaacct   1200

cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt gtttattata   1260

ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa aataacattc   1320

tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat caatgttcag   1380

ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc aatcacatta   1440

ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa gcacaccaag   1500

ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat aactcttgag   1560

gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa tgtgttggaa   1620

actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt cagggctgag   1680

tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc taataactgc   1740

ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac aatgttgtat   1800

ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt aactgccaag   1860

cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag tataaattat   1920

cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata acatgctgcc   1980

attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta tgtgctatca   2040

catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata tttattatga   2100

gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa   2160

aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt aacatattct   2220

aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg gatctgtaga   2280

agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt tttctatgaa   2340

ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct tgagcatcct   2400

gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt ctttagatga   2460

gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga aatgggggtg   2520

gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga   2580

gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa tctactgtaa   2640

agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag aaaaaaacat   2700

gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa ttcacagata   2760

tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc tggttcctct   2820

tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat gaaatctcac   2880

agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga aatgtcaatt   2940

tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca agtagtcagt   3000

ggaagagagt agagctcaaa actggattat caccttagca acttagaata gtttgaaata   3060

gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct attttttgta   3120

tagtattgga aaataaaaat gctataattt gggtatgggt tcttttgtat acattacctg   3180

cccattgagg aaaggggcaa gtccattatg caacttctct ccaaaccctt catattctgg   3240

atatgatact taaagagcca tgagcagcta cattctgcct atcagaaggc atttattaaa   3300

tgactgcttg ctgaagatgt gtccaaagag atcctacatt aaggtcattt gtcagaatga   3360

tgtttgtgtt tgtttagagt tggctgacct ccaactcctg gggtcaagga atcctactgc   3420

cttagcttcc caaatagcta ggactatagg catgcacccg gccatgtgtt ttatttatag   3480

ctcttaaagc ccagatgaag aaatcacatt tttgcccata gtgaagaaac atttggccat   3540

tgattagtcc ttattttcag tgactgtcct gttttcatta gattagagag accctgtgtg   3600

ggccacagtt aatataaacc attatcactt ttaagtaaac ctgcacatct tagatttcat   3660

aatttcctta ttgttctgac tcaaaatgaa ctaagagctt ttcacttttt gtttgtaagt   3720

tctcagagag tcgggtctgc aagtgctttt gcctgccagg attttgtact caaataaatg   3780

ctatttggca act                                                      3793


<210>  5846
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  5846

Met Asp Arg Gly Glu Gln Gly Arg Arg Arg Asn Pro Asp Ser Val Ser 
1               5                   10                  15


Ser Val Ser Ser Lys Arg Glu Ala Ser Ser Arg Asp Gln Ala Glu Thr 
            20                  25                  30


Trp Asn Gln Phe Ser Thr Gly Thr Lys Thr Glu His Cys Gln Arg Val 
        35                  40                  45


Ala Arg Arg Asp Ser Asn Ile Cys Leu Gln Glu Asp Ile 
    50                  55                  60


<210>  5847
<211>  3954
<212>  DNA
<213>  Homo sapiens

<400>  5847
gggcggcgcc gccgcgcccg acgcctctgg gggtggggac ttcgcgggag tcgccggcgg     60

aggcgaggag gagctctgcg cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg    120

ggggtgctgc agaggacacg aggcggcggg ctggagacat ggaccgcggc gagcaaggtc    180

tgctgagaac agacccagtc cctgaggaag gagaagatgt tgctgccacg atcagtgcca    240

cagagaccct ctcggaagag gagcaggaag agctaagaag agaacttgca aaggtagaag    300

aagaaatcca gactctgtct caagtgttag cagcaaaaga gaagcatcta gcagagatca    360

agcggaaact tggaatcaat tctctacagg aactaaaaca gaacattgcc aaagggtggc    420

aagacgtgac agcaacatct gcttacaaga agacatctga aaccttatcc caggctggac    480

agaaggcctc agctgctttt tcgtctgttg gctcagtcat caccaaaaag ctggaagatg    540

taaaaaactc cccaactttt aaatcatttg aagaaaaggt cgaaaactta aaggcaatag    600

ggggaaccaa gcctgctggt ggtgattttg gagaagtctt gaattcggct gcaaatgcta    660

gtgccaccac cacggagcct cttccagaaa agacacagga gagcctgtga gattcctacc    720

tttgttctgc tacccactgc cagatgctgc aagcgaggtc caagcacatc ttgtcaacat    780

gcattgccat gaatttctac cagatgtgct tttatttagc tttacatatt cctttgacca    840

aatagtttgt gggttaaaca aaatgaaaat atcttcacct ctattcttgg gaaacaccct    900

ttagtgtaca tttatgttcc tttatttagg aaacaccatt ataaaaacac ttatagtaaa    960

tggggacatt cactataatg atctaagaag ctacagattg tcatagttgt tttcctgctt   1020

tacaaaattg ctccagatct ggaatgccag tttgaccttt gtcttctata atatttcctt   1080

tttttcccct ctttgaatct ctgtatattt gattcttaac taaaattgtt ctcttaaata   1140

ttctgaatcc tggtaattaa aagtttgggt gtattttctt tacctccaag gaaagaacta   1200

ctagctacaa aaaatatttt ggaataagca ttgttttggt ataaggtaca tattttggtt   1260

gaagacacca gactgaagta aacagctgtg catccaattt attatagttt tgtaagtaac   1320

aatatgtaat caaacttcta ggtgacttga gagtggaacc tcctatatca ttatttagca   1380

ccgtttgtga cagtaaccat ttcagtgtat tgtttattat accacttata tcaacttatt   1440

tttcaccagg ttaaaatttt aatttctaca aaataacatt ctgaatcaag cacactgtat   1500

gttcagtagg ttgaactatg aacactgtca tcaatgttca gttcaaaagc ctgaaagttt   1560

agatctagaa gctggtaaaa atgacaatat caatcacatt aggggaacca ttgttgtctt   1620

cacttaatcc atttagcact atttaaaata agcacaccaa gttatatgac taatataact   1680

tgaaaatttt ttatactgag gggttggtga taactcttga ggatgtaatg cattaataaa   1740

aatcaactca tcattttcta cttgttttca atgtgttgga aactgtaaaa tgatactgta   1800

gaacctgtct cctactttga aaactgaatg tcagggctga gtgaatcaaa gtgtctagac   1860

atatttgcat agaggccaag gtattctatt ctaataactg cttactcaac actaccacct   1920

tttccttata ctgtatatga ttatggccta caatgttgta tttgttattt attaaattgt   1980

gattgtttta ttattgttta tgccaaatgt taactgccaa gcttggagtg acctaaagca   2040

ttttttaaaa gcatggctag atttacttca gtataaatta tcttatgaaa accaaatttt   2100

aaaagccaca ggtgttgatt gttataaaat aacatgctgc cattcttgat tgctagagtt   2160

tttgttagta ctttggatgc aattaaaact atgtgctatc acatgtgaaa agcttaataa   2220

attccatcta tcagtagtat aggtctcaat atttattatg agaccagtgg tctggaaaca   2280

gcttgttgta ccgaatcaac tggagtctat gcttaaaaaa aaaaaatttt tttttaacca   2340

tccttaaatt attgcttaat ggtatcatat taacatattc taaataaggg ctttaaggca   2400

caggctgttg aagcattttc tcagaggagt ggatctgtag aagtctgtct ttctatagaa   2460

atattgtgct tactcaagtg ttaaattatt ttttctatga actagtctac ttcttaaaat   2520

tcaaacatat tcttttgatc acattgtttc ttgagcatcc tgccctgcta ctaacttttc   2580

aacaaggcaa aatggagtaa agtggcaatt tctttagatg agtgaaatac cctcaagtct   2640

cttttctgcc caaaaaggga aaagtgatag aaatgggggt ggcaagtggg gtgagtggat   2700

gaaggtgggt attgggggtg gctgtgaaag aaaataatgg agaatcactt ttctagacat   2760

ctacctatac ttaatctaag aaacaaagta atctactgta aagtactctg ccccttgaaa   2820

gaagtattaa aaagagtgag gatggattta gaaaaaaaca tgaatttaga aatattcaaa   2880

atggtttttg tggcagattc aatattatga attcacagat atttaaagaa tgagaaacat   2940

agtaattagt agaaatgcca gaaacagttc ctggttcctc ttgtgtttga cactaagaaa   3000

atagcaagag tgtgaaatct cagatactta tgaaatctca cagatgtaag gactcaagtg   3060

tagaagaaaa tatccccttc ttacaaaaag aaatgtcaat ttatggagtt tgtgggaaat   3120

agggcaagaa ttcttatgct tatgagagcc aagtagtcag tggaagagag tagagctcaa   3180

aactggatta tcaccttagc aacttagaat agtttgaaat agaaaaaaag tatttaattt   3240

ggatctggat ctgttaagat atgcacagtc tattttttgt atagtattgg aaaataaaaa   3300

tgctataatt tgggtatggg ttcttttgta tacattacct gcccattgag gaaaggggca   3360

agtccattat gcaacttctc tccaaaccct tcatattctg gatatgatac ttaaagagcc   3420

atgagcagct acattctgcc tatcagaagg catttattaa atgactgctt gctgaagatg   3480

tgtccaaaga gatcctacat taaggtcatt tgtcagaatg atgtttgtgt ttgtttagag   3540

ttggctgacc tccaactcct ggggtcaagg aatcctactg ccttagcttc ccaaatagct   3600

aggactatag gcatgcaccc ggccatgtgt tttatttata gctcttaaag cccagatgaa   3660

gaaatcacat ttttgcccat agtgaagaaa catttggcca ttgattagtc cttattttca   3720

gtgactgtcc tgttttcatt agattagaga gaccctgtgt gggccacagt taatataaac   3780

cattatcact tttaagtaaa cctgcacatc ttagatttca taatttcctt attgttctga   3840

ctcaaaatga actaagagct tttcactttt tgtttgtaag ttctcagaga gtcgggtctg   3900

caagtgcttt tgcctgccag gattttgtac tcaaataaat gctatttggc aact         3954


<210>  5848
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  5848

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu 
    130                 135                 140


Lys Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val 
145                 150                 155                 160


Leu Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro 
                165                 170                 175


Glu Lys Thr Gln Glu Ser Leu 
            180


<210>  5849
<211>  4063
<212>  DNA
<213>  Homo sapiens

<400>  5849
ggttgggtga cgccccagga aagcgctcca ggccgagggc gggcggcgcc gccgcgcccg     60

acgcctctgg gggtggggac ttcgcgggag tcgccggcgg aggcgaggag gagctctgcg    120

cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg ggggtgctgc agaggacacg    180

aggcggcggg ctggagacat ggaccgcggc gagcaaggtc tgctgagaac agacccagtc    240

cctgaggaag gagaagatgt tgctgccacg atcagtgcca cagagaccct ctcggaagag    300

gagcaggaag agctaagaag agaacttgca aaggtagaag aagaaatcca gactctgtct    360

caagtgttag cagcaaaaga gaagcatcta gcagagatca agcggaaact tggaatcaat    420

tctctacagg aactaaaaca gaacattgcc aaagggtggc aagacgtgac agcaacatct    480

gcttacaaga agacatctga aaccttatcc caggctggac agaaggcctc agctgctttt    540

tcgtctgttg gctcagtcat caccaaaaag ctggaagatg taaaattgca agccttttca    600

cattccttta gtatacgttc cattcagcat tcaattagca tgcctgctat gagaaactcc    660

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag    720

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc    780

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct    840

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg    900

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg    960

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1020

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1080

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1140

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1200

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1260

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1320

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1380

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1440

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1500

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1560

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1620

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1680

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   1740

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   1800

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   1860

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   1920

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   1980

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2040

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2100

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2160

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2220

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2280

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2340

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2400

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2460

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2520

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2580

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2640

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   2700

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   2760

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   2820

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   2880

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   2940

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3000

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3060

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3120

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3180

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3240

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3300

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3360

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3420

gggtatgggt tcttttgtat acattacctg cccattgagg aaaggggcaa gtccattatg   3480

caacttctct ccaaaccctt catattctgg atatgatact taaagagcca tgagcagcta   3540

cattctgcct atcagaaggc atttattaaa tgactgcttg ctgaagatgt gtccaaagag   3600

atcctacatt aaggtcattt gtcagaatga tgtttgtgtt tgtttagagt tggctgacct   3660

ccaactcctg gggtcaagga atcctactgc cttagcttcc caaatagcta ggactatagg   3720

catgcacccg gccatgtgtt ttatttatag ctcttaaagc ccagatgaag aaatcacatt   3780

tttgcccata gtgaagaaac atttggccat tgattagtcc ttattttcag tgactgtcct   3840

gttttcatta gattagagag accctgtgtg ggccacagtt aatataaacc attatcactt   3900

ttaagtaaac ctgcacatct tagatttcat aatttcctta ttgttctgac tcaaaatgaa   3960

ctaagagctt ttcacttttt gtttgtaagt tctcagagag tcgggtctgc aagtgctttt   4020

gcctgccagg attttgtact caaataaatg ctatttggca act                     4063


<210>  5850
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  5850

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Leu Gln Ala Phe Ser His Ser Phe Ser Ile Arg Ser Ile Gln His 
    130                 135                 140


Ser Ile Ser Met Pro Ala Met Arg Asn Ser Pro Thr Phe Lys Ser Phe 
145                 150                 155                 160


Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro Ala 
                165                 170                 175


Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser Ala 
            180                 185                 190


Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
        195                 200                 205


<210>  5851
<211>  1817
<212>  DNA
<213>  Homo sapiens

<400>  5851
aatgttatgc aagtgtagag acagacagtt cactaggtac tttaaaataa tagaccttac     60

aaagttttct agacagactt cctgtgaaga acaaggagca gggggaaagg ggaaggggta    120

gaatttacca atctgaatat ttcagcaagg gagaatgcat gagttttact ataaaaccac    180

actgaacatt gcaacaatac taaattccat acatatataa taatcactga gctataaggt    240

tgctgatgta tttgttcttg aaagtgaatt agagttactt tatgcagaat cagctagttt    300

tatgtttcat aatgtctttc ccttttttga actttttttt aagtctaaag tagggggaac    360

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    420

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    480

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    540

catgaatttc taccagatgt gcttttattt agctttacat attcttatga aaaccaaatt    600

ttaaaagcca caggtgttga ttgttataaa ataacatgct gccattcttg attgctagag    660

tttttgttag tactttggat gcaattaaaa ctatgtgcta tcacatgtga aaagcttaat    720

aaattccatc tatcagtagt ataggtctca atatttatta tgagaccagt ggtctggaaa    780

cagcttgttg taccgaatca actggagtct atgcttaaaa aaaaaaaatt tttttttaac    840

catccttaaa ttattgctta atggtatcat attaacatat tctaaataag ggctttaagg    900

cacaggctgt tgaagcattt tctcagagga gtggatctgt agaagtctgt ctttctatag    960

aaatattgtg cttactcaag tgttaaatta ttttttctat gaactagtct acttcttaaa   1020

attcaaacat attcttttga tcacattgtt tcttgagcat cctgccctgc tactaacttt   1080

tcaacaaggc aaaatggagt aaagtggcaa tttctttaga tgagtgaaat accctcaagt   1140

ctcttttctg cccaaaaagg gaaaagtgat agaaatgggg gtggcaagtg gggtgagtgg   1200

atgaaggtgg gtattggggg tggctgtgaa agaaaataat ggagaatcac ttttctagac   1260

atctacctat acttaatcta agaaacaaag taatctactg taaagtactc tgccccttga   1320

aagaagtatt aaaaagagtg aggatggatt tagaaaaaaa catgaattta gaaatattca   1380

aaatggtttt tgtggcagat tcaatattat gaattcacag atatttaaag aatgagaaac   1440

atagtaatta gtagaaatgc cagaaacagt tcctggttcc tcttgtgttt gacactaaga   1500

aaatagcaag agtgtgaaat ctcagatact tatgaaatct cacagatgta aggactcaag   1560

tgtagaagaa aatatcccct tcttacaaaa agaaatgtca atttatggag tttgtgggaa   1620

atagggcaag aattcttatg cttatgagag ccaagtagtc agtggaagag agtagagctc   1680

aaaactggat tatcacctta gcaacttaga atagtttgaa atagaaaaaa agtatttaat   1740

ttggatctgg atctgttaag atatgcacag tctatttttt gtatagtatt ggaaaataaa   1800

aatgctataa tttgggt                                                  1817


<210>  5852
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  5852

Met His Cys His Glu Phe Leu Pro Asp Val Leu Leu Phe Ser Phe Thr 
1               5                   10                  15


Tyr Ser Tyr Glu Asn Gln Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr 
            20                  25                  30


Lys Ile Thr Cys Cys His Ser 
        35


<210>  5853
<211>  3014
<212>  DNA
<213>  Homo sapiens

<400>  5853
attacttatg tctgagactg gccctgttca tggaatcaaa tgcatactct taaaatatta     60

gatcagaaat tgagaatctt acattataaa tacttgtatg tacctgcaca tatatggtac    120

agattatatc tgttcttttg ccgattgaga ataatgttga agaggaatca attatatttt    180

caaactagtt ggattttttt tcagtatttg tatttactat ttgtttttct tttctctcca    240

tagaaactcc ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg    300

gggaaccaag cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag    360

tgccaccacc acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct    420

ttgttctgct acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg    480

cattgccatg aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa    540

atagtttgtg ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt    600

tagtgtacat ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat    660

ggggacattc actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt    720

acaaaattgc tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt    780

ttttcccctc tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat    840

tctgaatcct ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac    900

tagctacaaa aaatattttg gaataagcat tgttttggta taaggtacat attttggttg    960

aagacaccag actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca   1020

atatgtaatc aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac   1080

cgtttgtgac agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt   1140

ttcaccaggt taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg   1200

ttcagtaggt tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta   1260

gatctagaag ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc   1320

acttaatcca tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt   1380

gaaaattttt tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa   1440

atcaactcat cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag   1500

aacctgtctc ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca   1560

tatttgcata gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt   1620

ttccttatac tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg   1680

attgttttat tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat   1740

tttttaaaag catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta   1800

aaagccacag gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt   1860

ttgttagtac tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa   1920

ttccatctat cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag   1980

cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat   2040

ccttaaatta ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac   2100

aggctgttga agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa   2160

tattgtgctt actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt   2220

caaacatatt cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca   2280

acaaggcaaa atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc   2340

ttttctgccc aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg   2400

aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc   2460

tacctatact taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag   2520

aagtattaaa aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa   2580

tggtttttgt ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata   2640

gtaattagta gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa   2700

tagcaagagt gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt   2760

agaagaaaat atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata   2820

gggcaagaat tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa   2880

actggattat caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg   2940

gatctggatc tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat   3000

gctataattt gggt                                                     3014


<210>  5854
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  5854

Met His Thr Leu Lys Ile Leu Asp Gln Lys Leu Arg Ile Leu His Tyr 
1               5                   10                  15


Lys Tyr Leu Tyr Val Pro Ala His Ile Trp Tyr Arg Leu Tyr Leu Phe 
            20                  25                  30


Phe Cys Arg Leu Arg Ile Met Leu Lys Arg Asn Gln Leu Tyr Phe Gln 
        35                  40                  45


Thr Ser Trp Ile Phe Phe Gln Tyr Leu Tyr Leu Leu Phe Val Phe Leu 
    50                  55                  60


Phe Ser Pro 
65


<210>  5855
<211>  2948
<212>  DNA
<213>  Homo sapiens

<400>  5855
actccttcaa accagtacct ggaaggctca tctaaggtct tctaggccta gcattctaac     60

atcaaatgat catctgatga tcatttaagg ttgttgaaaa attctggttg tgaacttctt    120

tgtcttttta gttcttcatg atcatgcagg attgcaagcc ttttcacatt cctttagaaa    180

ctccccaact tttaaatcat ttgaagaaaa ggtcgaaaac ttaaaggcaa tagggggaac    240

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    300

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    360

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    420

catgaatttc taccagatgt gcttttattt agctttacat attcctttga ccaaatagtt    480

tgtgggttaa acaaaatgaa aatatcttca cctctattct tgggaaacac cctttagtgt    540

acatttatgt tcctttattt aggaaacacc attataaaaa cacttatagt aaatggggac    600

attcactata atgatctaag aagctacaga ttgtcatagt tgttttcctg ctttacaaaa    660

ttgctccaga tctggaatgc cagtttgacc tttgtcttct ataatatttc ctttttttcc    720

cctctttgaa tctctgtata tttgattctt aactaaaatt gttctcttaa atattctgaa    780

tcctggtaat taaaagtttg ggtgtatttt ctttacctcc aaggaaagaa ctactagcta    840

caaaaaatat tttggaataa gcattgtttt ggtataaggt acatattttg gttgaagaca    900

ccagactgaa gtaaacagct gtgcatccaa tttattatag ttttgtaagt aacaatatgt    960

aatcaaactt ctaggtgact tgagagtgga acctcctata tcattattta gcaccgtttg   1020

tgacagtaac catttcagtg tattgtttat tataccactt atatcaactt atttttcacc   1080

aggttaaaat tttaatttct acaaaataac attctgaatc aagcacactg tatgttcagt   1140

aggttgaact atgaacactg tcatcaatgt tcagttcaaa agcctgaaag tttagatcta   1200

gaagctggta aaaatgacaa tatcaatcac attaggggaa ccattgttgt cttcacttaa   1260

tccatttagc actatttaaa ataagcacac caagttatat gactaatata acttgaaaat   1320

tttttatact gaggggttgg tgataactct tgaggatgta atgcattaat aaaaatcaac   1380

tcatcatttt ctacttgttt tcaatgtgtt ggaaactgta aaatgatact gtagaacctg   1440

tctcctactt tgaaaactga atgtcagggc tgagtgaatc aaagtgtcta gacatatttg   1500

catagaggcc aaggtattct attctaataa ctgcttactc aacactacca ccttttcctt   1560

atactgtata tgattatggc ctacaatgtt gtatttgtta tttattaaat tgtgattgtt   1620

ttattattgt ttatgccaaa tgttaactgc caagcttgga gtgacctaaa gcatttttta   1680

aaagcatggc tagatttact tcagtataaa ttatcttatg aaaaccaaat tttaaaagcc   1740

acaggtgttg attgttataa aataacatgc tgccattctt gattgctaga gtttttgtta   1800

gtactttgga tgcaattaaa actatgtgct atcacatgtg aaaagcttaa taaattccat   1860

ctatcagtag tataggtctc aatatttatt atgagaccag tggtctggaa acagcttgtt   1920

gtaccgaatc aactggagtc tatgcttaaa aaaaaaaaat ttttttttaa ccatccttaa   1980

attattgctt aatggtatca tattaacata ttctaaataa gggctttaag gcacaggctg   2040

ttgaagcatt ttctcagagg agtggatctg tagaagtctg tctttctata gaaatattgt   2100

gcttactcaa gtgttaaatt attttttcta tgaactagtc tacttcttaa aattcaaaca   2160

tattcttttg atcacattgt ttcttgagca tcctgccctg ctactaactt ttcaacaagg   2220

caaaatggag taaagtggca atttctttag atgagtgaaa taccctcaag tctcttttct   2280

gcccaaaaag ggaaaagtga tagaaatggg ggtggcaagt ggggtgagtg gatgaaggtg   2340

ggtattgggg gtggctgtga aagaaaataa tggagaatca cttttctaga catctaccta   2400

tacttaatct aagaaacaaa gtaatctact gtaaagtact ctgccccttg aaagaagtat   2460

taaaaagagt gaggatggat ttagaaaaaa acatgaattt agaaatattc aaaatggttt   2520

ttgtggcaga ttcaatatta tgaattcaca gatatttaaa gaatgagaaa catagtaatt   2580

agtagaaatg ccagaaacag ttcctggttc ctcttgtgtt tgacactaag aaaatagcaa   2640

gagtgtgaaa tctcagatac ttatgaaatc tcacagatgt aaggactcaa gtgtagaaga   2700

aaatatcccc ttcttacaaa aagaaatgtc aatttatgga gtttgtggga aatagggcaa   2760

gaattcttat gcttatgaga gccaagtagt cagtggaaga gagtagagct caaaactgga   2820

ttatcacctt agcaacttag aatagtttga aatagaaaaa aagtatttaa tttggatctg   2880

gatctgttaa gatatgcaca gtctattttt tgtatagtat tggaaaataa aaatgctata   2940

atttgggt                                                            2948


<210>  5856
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5856

Met Glu Asn His Phe Ser Arg His Leu Pro Ile Leu Asn Leu Arg Asn 
1               5                   10                  15


Lys Val Ile Tyr Cys Lys Val Leu Cys Pro Leu Lys Glu Val Leu Lys 
            20                  25                  30


Arg Val Arg Met Asp Leu Glu Lys Asn Met Asn Leu Glu Ile Phe Lys 
        35                  40                  45


Met Val Phe Val Ala Asp Ser Ile Leu 
    50                  55


<210>  5857
<211>  2936
<212>  DNA
<213>  Homo sapiens

<400>  5857
agagtgaggg agggcactcc ttcaaaccag tacctggaag gctcatctaa ggtcttctag     60

gcctagcatt ctaacatcaa atgatcatct gatgatcatt taaggttgtt gaaaaattct    120

ggttgtgaac ttctttgtct ttttagttct tcatgatcat gcaggaaact ccccaacttt    180

taaatcattt gaagaaaagg tcgaaaactt aaaggcaata gggggaacca agcctgctgg    240

tggtgatttt ggagaagtct tgaattcggc tgcaaatgct agtgccacca ccacggagcc    300

tcttccagaa aagacacagg agagcctgtg agattcctac ctttgttctg ctacccactg    360

ccagatgctg caagcgaggt ccaagcacat cttgtcaaca tgcattgcca tgaatttcta    420

ccagatgtgc ttttatttag ctttacatat tcctttgacc aaatagtttg tgggttaaac    480

aaaatgaaaa tatcttcacc tctattcttg ggaaacaccc tttagtgtac atttatgttc    540

ctttatttag gaaacaccat tataaaaaca cttatagtaa atggggacat tcactataat    600

gatctaagaa gctacagatt gtcatagttg ttttcctgct ttacaaaatt gctccagatc    660

tggaatgcca gtttgacctt tgtcttctat aatatttcct ttttttcccc tctttgaatc    720

tctgtatatt tgattcttaa ctaaaattgt tctcttaaat attctgaatc ctggtaatta    780

aaagtttggg tgtattttct ttacctccaa ggaaagaact actagctaca aaaaatattt    840

tggaataagc attgttttgg tataaggtac atattttggt tgaagacacc agactgaagt    900

aaacagctgt gcatccaatt tattatagtt ttgtaagtaa caatatgtaa tcaaacttct    960

aggtgacttg agagtggaac ctcctatatc attatttagc accgtttgtg acagtaacca   1020

tttcagtgta ttgtttatta taccacttat atcaacttat ttttcaccag gttaaaattt   1080

taatttctac aaaataacat tctgaatcaa gcacactgta tgttcagtag gttgaactat   1140

gaacactgtc atcaatgttc agttcaaaag cctgaaagtt tagatctaga agctggtaaa   1200

aatgacaata tcaatcacat taggggaacc attgttgtct tcacttaatc catttagcac   1260

tatttaaaat aagcacacca agttatatga ctaatataac ttgaaaattt tttatactga   1320

ggggttggtg ataactcttg aggatgtaat gcattaataa aaatcaactc atcattttct   1380

acttgttttc aatgtgttgg aaactgtaaa atgatactgt agaacctgtc tcctactttg   1440

aaaactgaat gtcagggctg agtgaatcaa agtgtctaga catatttgca tagaggccaa   1500

ggtattctat tctaataact gcttactcaa cactaccacc ttttccttat actgtatatg   1560

attatggcct acaatgttgt atttgttatt tattaaattg tgattgtttt attattgttt   1620

atgccaaatg ttaactgcca agcttggagt gacctaaagc attttttaaa agcatggcta   1680

gatttacttc agtataaatt atcttatgaa aaccaaattt taaaagccac aggtgttgat   1740

tgttataaaa taacatgctg ccattcttga ttgctagagt ttttgttagt actttggatg   1800

caattaaaac tatgtgctat cacatgtgaa aagcttaata aattccatct atcagtagta   1860

taggtctcaa tatttattat gagaccagtg gtctggaaac agcttgttgt accgaatcaa   1920

ctggagtcta tgcttaaaaa aaaaaaattt ttttttaacc atccttaaat tattgcttaa   1980

tggtatcata ttaacatatt ctaaataagg gctttaaggc acaggctgtt gaagcatttt   2040

ctcagaggag tggatctgta gaagtctgtc tttctataga aatattgtgc ttactcaagt   2100

gttaaattat tttttctatg aactagtcta cttcttaaaa ttcaaacata ttcttttgat   2160

cacattgttt cttgagcatc ctgccctgct actaactttt caacaaggca aaatggagta   2220

aagtggcaat ttctttagat gagtgaaata ccctcaagtc tcttttctgc ccaaaaaggg   2280

aaaagtgata gaaatggggg tggcaagtgg ggtgagtgga tgaaggtggg tattgggggt   2340

ggctgtgaaa gaaaataatg gagaatcact tttctagaca tctacctata cttaatctaa   2400

gaaacaaagt aatctactgt aaagtactct gccccttgaa agaagtatta aaaagagtga   2460

ggatggattt agaaaaaaac atgaatttag aaatattcaa aatggttttt gtggcagatt   2520

caatattatg aattcacaga tatttaaaga atgagaaaca tagtaattag tagaaatgcc   2580

agaaacagtt cctggttcct cttgtgtttg acactaagaa aatagcaaga gtgtgaaatc   2640

tcagatactt atgaaatctc acagatgtaa ggactcaagt gtagaagaaa atatcccctt   2700

cttacaaaaa gaaatgtcaa tttatggagt ttgtgggaaa tagggcaaga attcttatgc   2760

ttatgagagc caagtagtca gtggaagaga gtagagctca aaactggatt atcaccttag   2820

caacttagaa tagtttgaaa tagaaaaaaa gtatttaatt tggatctgga tctgttaaga   2880

tatgcacagt ctattttttg tatagtattg gaaaataaaa atgctataat ttgggt       2936


<210>  5858
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5858

Met Glu Asn His Phe Ser Arg His Leu Pro Ile Leu Asn Leu Arg Asn 
1               5                   10                  15


Lys Val Ile Tyr Cys Lys Val Leu Cys Pro Leu Lys Glu Val Leu Lys 
            20                  25                  30


Arg Val Arg Met Asp Leu Glu Lys Asn Met Asn Leu Glu Ile Phe Lys 
        35                  40                  45


Met Val Phe Val Ala Asp Ser Ile Leu 
    50                  55


<210>  5859
<211>  3104
<212>  DNA
<213>  Homo sapiens

<400>  5859
ctttctggct ggactagggc actgcagaag attgtgcctg agcttagggt tgagcatacg     60

aagatgtggt gatgccgctc tgctggttat gaaggatttt agaagttctg aaaaatgttt    120

tctctttttg agagttctcc agcaggtggt gaccactgca cttgaaacaa ttgatattag    180

aaaagatgag ctgacccttc ttttgctctg tgtgtttata atttaatata gttacaagaa    240

gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg    300

ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga    360

agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg    420

agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa    480

gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca    540

agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt    600

ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata    660

tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga    720

aacaccatta taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc    780

tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt    840

ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg    900

attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg    960

tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat   1020

tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc   1080

atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag   1140

agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt   1200

gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa   1260

aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat   1320

caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc   1380

aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa   1440

gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat   1500

aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa   1560

tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt   1620

cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc   1680

taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac   1740

aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt   1800

aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag   1860

tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata   1920

acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta   1980

tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata   2040

tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg   2100

cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt   2160

aacatattct aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg   2220

gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt   2280

tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct   2340

tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt   2400

ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga   2460

aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga   2520

aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa   2580

tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag   2640

aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa   2700

ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc   2760

tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat   2820

gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga   2880

aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca   2940

agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca acttagaata   3000

gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct   3060

attttttgta tagtattgga aaataaaaat gctataattt gggt                    3104


<210>  5860
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5860

Met Glu Asn His Phe Ser Arg His Leu Pro Ile Leu Asn Leu Arg Asn 
1               5                   10                  15


Lys Val Ile Tyr Cys Lys Val Leu Cys Pro Leu Lys Glu Val Leu Lys 
            20                  25                  30


Arg Val Arg Met Asp Leu Glu Lys Asn Met Asn Leu Glu Ile Phe Lys 
        35                  40                  45


Met Val Phe Val Ala Asp Ser Ile Leu 
    50                  55


<210>  5861
<211>  3202
<212>  DNA
<213>  Homo sapiens

<400>  5861
ggagcttaaa tagggatttt acttagattt tgcactttaa aaaatggttt aaatccccaa     60

ccaggtctgc tgagaacaga cccagtccct gaggaaggag aagatgttgc tgccacgatc    120

agtgccacag agaccctctc ggaagaggag caggaagagc taagaagaga acttgcaaag    180

gtagaagaag aaatccagac tctgtctcaa gtgttagcag caaaagagaa gcatctagca    240

gagatcaagc ggaaacttgg aatcaattct ctacaggaac taaaacagaa cattgccaaa    300

gggtggcaag acgtgacagc aacatctgct tacaagaaga catctgaaac cttatcccag    360

gctggacaga aggcctcagc tgctttttcg tctgttggct cagtcatcac caaaaagctg    420

gaagatgtaa aaaactcccc aacttttaaa tcatttgaag aaaaggtcga aaacttaaag    480

gcaatagggg gaaccaagcc tgctggtggt gattttggag aagtcttgaa ttcggctgca    540

aatgctagtg ccaccaccac ggagcctctt ccagaaaaga cacaggagag cctgtgagat    600

tcctaccttt gttctgctac ccactgccag atgctgcaag cgaggtccaa gcacatcttg    660

tcaacatgca ttgccatgaa tttctaccag atgtgctttt atttagcttt acatattcct    720

ttgaccaaat agtttgtggg ttaaacaaaa tgaaaatatc ttcacctcta ttcttgggaa    780

acacccttta gtgtacattt atgttccttt atttaggaaa caccattata aaaacactta    840

tagtaaatgg ggacattcac tataatgatc taagaagcta cagattgtca tagttgtttt    900

cctgctttac aaaattgctc cagatctgga atgccagttt gacctttgtc ttctataata    960

tttccttttt ttcccctctt tgaatctctg tatatttgat tcttaactaa aattgttctc   1020

ttaaatattc tgaatcctgg taattaaaag tttgggtgta ttttctttac ctccaaggaa   1080

agaactacta gctacaaaaa atattttgga ataagcattg ttttggtata aggtacatat   1140

tttggttgaa gacaccagac tgaagtaaac agctgtgcat ccaatttatt atagttttgt   1200

aagtaacaat atgtaatcaa acttctaggt gacttgagag tggaacctcc tatatcatta   1260

tttagcaccg tttgtgacag taaccatttc agtgtattgt ttattatacc acttatatca   1320

acttattttt caccaggtta aaattttaat ttctacaaaa taacattctg aatcaagcac   1380

actgtatgtt cagtaggttg aactatgaac actgtcatca atgttcagtt caaaagcctg   1440

aaagtttaga tctagaagct ggtaaaaatg acaatatcaa tcacattagg ggaaccattg   1500

ttgtcttcac ttaatccatt tagcactatt taaaataagc acaccaagtt atatgactaa   1560

tataacttga aaatttttta tactgagggg ttggtgataa ctcttgagga tgtaatgcat   1620

taataaaaat caactcatca ttttctactt gttttcaatg tgttggaaac tgtaaaatga   1680

tactgtagaa cctgtctcct actttgaaaa ctgaatgtca gggctgagtg aatcaaagtg   1740

tctagacata tttgcataga ggccaaggta ttctattcta ataactgctt actcaacact   1800

accacctttt ccttatactg tatatgatta tggcctacaa tgttgtattt gttatttatt   1860

aaattgtgat tgttttatta ttgtttatgc caaatgttaa ctgccaagct tggagtgacc   1920

taaagcattt tttaaaagca tggctagatt tacttcagta taaattatct tatgaaaacc   1980

aaattttaaa agccacaggt gttgattgtt ataaaataac atgctgccat tcttgattgc   2040

tagagttttt gttagtactt tggatgcaat taaaactatg tgctatcaca tgtgaaaagc   2100

ttaataaatt ccatctatca gtagtatagg tctcaatatt tattatgaga ccagtggtct   2160

ggaaacagct tgttgtaccg aatcaactgg agtctatgct taaaaaaaaa aaattttttt   2220

ttaaccatcc ttaaattatt gcttaatggt atcatattaa catattctaa ataagggctt   2280

taaggcacag gctgttgaag cattttctca gaggagtgga tctgtagaag tctgtctttc   2340

tatagaaata ttgtgcttac tcaagtgtta aattattttt tctatgaact agtctacttc   2400

ttaaaattca aacatattct tttgatcaca ttgtttcttg agcatcctgc cctgctacta   2460

acttttcaac aaggcaaaat ggagtaaagt ggcaatttct ttagatgagt gaaataccct   2520

caagtctctt ttctgcccaa aaagggaaaa gtgatagaaa tgggggtggc aagtggggtg   2580

agtggatgaa ggtgggtatt gggggtggct gtgaaagaaa ataatggaga atcacttttc   2640

tagacatcta cctatactta atctaagaaa caaagtaatc tactgtaaag tactctgccc   2700

cttgaaagaa gtattaaaaa gagtgaggat ggatttagaa aaaaacatga atttagaaat   2760

attcaaaatg gtttttgtgg cagattcaat attatgaatt cacagatatt taaagaatga   2820

gaaacatagt aattagtaga aatgccagaa acagttcctg gttcctcttg tgtttgacac   2880

taagaaaata gcaagagtgt gaaatctcag atacttatga aatctcacag atgtaaggac   2940

tcaagtgtag aagaaaatat ccccttctta caaaaagaaa tgtcaattta tggagtttgt   3000

gggaaatagg gcaagaattc ttatgcttat gagagccaag tagtcagtgg aagagagtag   3060

agctcaaaac tggattatca ccttagcaac ttagaatagt ttgaaataga aaaaaagtat   3120

ttaatttgga tctggatctg ttaagatatg cacagtctat tttttgtata gtattggaaa   3180

ataaaaatgc tataatttgg gt                                            3202


<210>  5862
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  5862

Met Glu Asn His Phe Ser Arg His Leu Pro Ile Leu Asn Leu Arg Asn 
1               5                   10                  15


Lys Val Ile Tyr Cys Lys Val Leu Cys Pro Leu Lys Glu Val Leu Lys 
            20                  25                  30


Arg Val Arg Met Asp Leu Glu Lys Asn Met Asn Leu Glu Ile Phe Lys 
        35                  40                  45


Met Val Phe Val Ala Asp Ser Ile Leu 
    50                  55


<210>  5863
<211>  3724
<212>  DNA
<213>  Homo sapiens

<400>  5863
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cgaggagcaa gcttctagca gcagaaaccg aactgctctg tcttctgtat tgagagccat    840

ctgcagagct gttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca    900

gctgcttttt cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc    960

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag   1020

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc   1080

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct   1140

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg   1200

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg   1260

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1320

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1380

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1440

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1500

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1560

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1620

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1680

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1740

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1800

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1860

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1920

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1980

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   2040

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   2100

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   2160

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   2220

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   2280

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2340

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2400

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2460

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2520

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2580

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2640

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2700

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2760

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2820

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2880

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2940

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   3000

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   3060

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   3120

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   3180

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   3240

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3300

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3360

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3420

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3480

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3540

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3600

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3660

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3720

gggt                                                                3724


<210>  5864
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5864

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Arg Ser Lys Leu Leu Ala Ala Glu Thr 
    130                 135                 140


Glu Leu Leu Cys Leu Leu Tyr 
145                 150


<210>  5865
<211>  3723
<212>  DNA
<213>  Homo sapiens

<400>  5865
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaattgcaa gccttttcac    900

attcctttag tatacgttcc attcagcatt caattagcat gcctgctatg agaaactccc    960

caacttttaa atcatttgaa gaaaaggtcg aaaacttaaa ggcaataggg ggaaccaagc   1020

ctgctggtgg tgattttgga gaagtcttga attcggctgc aaatgctagt gccaccacca   1080

cggagcctct tccagaaaag acacaggaga gcctgtgaga ttcctacctt tgttctgcta   1140

cccactgcca gatgctgcaa gcgaggtcca agcacatctt gtcaacatgc attgccatga   1200

atttctacca gatgtgcttt tatttagctt tacatattcc tttgaccaaa tagtttgtgg   1260

gttaaacaaa atgaaaatat cttcacctct attcttggga aacacccttt agtgtacatt   1320

tatgttcctt tatttaggaa acaccattat aaaaacactt atagtaaatg gggacattca   1380

ctataatgat ctaagaagct acagattgtc atagttgttt tcctgcttta caaaattgct   1440

ccagatctgg aatgccagtt tgacctttgt cttctataat atttcctttt tttcccctct   1500

ttgaatctct gtatatttga ttcttaacta aaattgttct cttaaatatt ctgaatcctg   1560

gtaattaaaa gtttgggtgt attttcttta cctccaagga aagaactact agctacaaaa   1620

aatattttgg aataagcatt gttttggtat aaggtacata ttttggttga agacaccaga   1680

ctgaagtaaa cagctgtgca tccaatttat tatagttttg taagtaacaa tatgtaatca   1740

aacttctagg tgacttgaga gtggaacctc ctatatcatt atttagcacc gtttgtgaca   1800

gtaaccattt cagtgtattg tttattatac cacttatatc aacttatttt tcaccaggtt   1860

aaaattttaa tttctacaaa ataacattct gaatcaagca cactgtatgt tcagtaggtt   1920

gaactatgaa cactgtcatc aatgttcagt tcaaaagcct gaaagtttag atctagaagc   1980

tggtaaaaat gacaatatca atcacattag gggaaccatt gttgtcttca cttaatccat   2040

ttagcactat ttaaaataag cacaccaagt tatatgacta atataacttg aaaatttttt   2100

atactgaggg gttggtgata actcttgagg atgtaatgca ttaataaaaa tcaactcatc   2160

attttctact tgttttcaat gtgttggaaa ctgtaaaatg atactgtaga acctgtctcc   2220

tactttgaaa actgaatgtc agggctgagt gaatcaaagt gtctagacat atttgcatag   2280

aggccaaggt attctattct aataactgct tactcaacac taccaccttt tccttatact   2340

gtatatgatt atggcctaca atgttgtatt tgttatttat taaattgtga ttgttttatt   2400

attgtttatg ccaaatgtta actgccaagc ttggagtgac ctaaagcatt ttttaaaagc   2460

atggctagat ttacttcagt ataaattatc ttatgaaaac caaattttaa aagccacagg   2520

tgttgattgt tataaaataa catgctgcca ttcttgattg ctagagtttt tgttagtact   2580

ttggatgcaa ttaaaactat gtgctatcac atgtgaaaag cttaataaat tccatctatc   2640

agtagtatag gtctcaatat ttattatgag accagtggtc tggaaacagc ttgttgtacc   2700

gaatcaactg gagtctatgc ttaaaaaaaa aaaatttttt tttaaccatc cttaaattat   2760

tgcttaatgg tatcatatta acatattcta aataagggct ttaaggcaca ggctgttgaa   2820

gcattttctc agaggagtgg atctgtagaa gtctgtcttt ctatagaaat attgtgctta   2880

ctcaagtgtt aaattatttt ttctatgaac tagtctactt cttaaaattc aaacatattc   2940

ttttgatcac attgtttctt gagcatcctg ccctgctact aacttttcaa caaggcaaaa   3000

tggagtaaag tggcaatttc tttagatgag tgaaataccc tcaagtctct tttctgccca   3060

aaaagggaaa agtgatagaa atgggggtgg caagtggggt gagtggatga aggtgggtat   3120

tgggggtggc tgtgaaagaa aataatggag aatcactttt ctagacatct acctatactt   3180

aatctaagaa acaaagtaat ctactgtaaa gtactctgcc ccttgaaaga agtattaaaa   3240

agagtgagga tggatttaga aaaaaacatg aatttagaaa tattcaaaat ggtttttgtg   3300

gcagattcaa tattatgaat tcacagatat ttaaagaatg agaaacatag taattagtag   3360

aaatgccaga aacagttcct ggttcctctt gtgtttgaca ctaagaaaat agcaagagtg   3420

tgaaatctca gatacttatg aaatctcaca gatgtaagga ctcaagtgta gaagaaaata   3480

tccccttctt acaaaaagaa atgtcaattt atggagtttg tgggaaatag ggcaagaatt   3540

cttatgctta tgagagccaa gtagtcagtg gaagagagta gagctcaaaa ctggattatc   3600

accttagcaa cttagaatag tttgaaatag aaaaaaagta tttaatttgg atctggatct   3660

gttaagatat gcacagtcta ttttttgtat agtattggaa aataaaaatg ctataatttg   3720

ggt                                                                 3723


<210>  5866
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  5866

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Leu Gln Ala Phe Ser His Ser 
                165                 170                 175


Phe Ser Ile Arg Ser Ile Gln His Ser Ile Ser Met Pro Ala Met Arg 
            180                 185                 190


Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu Lys 
        195                 200                 205


Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val Leu 
    210                 215                 220


Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro Glu 
225                 230                 235                 240


Lys Thr Gln Glu Ser Leu 
                245


<210>  5867
<211>  3654
<212>  DNA
<213>  Homo sapiens

<400>  5867
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta    900

aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg    960

gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc   1020

ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc   1080

agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc   1140

agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa   1200

aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct   1260

ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc actataatga   1320

tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg   1380

gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc   1440

tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa   1500

agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg   1560

gaataagcat tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa   1620

acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag   1680

gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt   1740

tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta   1800

atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga   1860

acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa   1920

tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta   1980

tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg   2040

ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac   2100

ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa   2160

aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg   2220

tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat   2280

tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat   2340

gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga   2400

tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg   2460

ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca   2520

attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtagtata   2580

ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac cgaatcaact   2640

ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta ttgcttaatg   2700

gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga agcattttct   2760

cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt actcaagtgt   2820

taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt cttttgatca   2880

cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa atggagtaaa   2940

gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa   3000

aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg   3060

ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact taatctaaga   3120

aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa aagagtgagg   3180

atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt ggcagattca   3240

atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta gaaatgccag   3300

aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc   3360

agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat atccccttct   3420

tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat tcttatgctt   3480

atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat caccttagca   3540

acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc tgttaagata   3600

tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt gggt         3654


<210>  5868
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  5868

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Asn Ser Pro Thr Phe Lys Ser 
                165                 170                 175


Phe Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro 
            180                 185                 190


Ala Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser 
        195                 200                 205


Ala Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
    210                 215                 220


<210>  5869
<211>  3154
<212>  DNA
<213>  Homo sapiens

<400>  5869
gggagtcgcc ggcggaggcg aggaggagct ctgcgcggcg cggcgggcga tccgagccgg     60

gacgggctgc aggcgggggt gctgcagagg acacgaggcg gcgggctgga gacatggacc    120

gcggcgagca aggtagaaga agaaatccag actctgtctc aagtgttagc agcaaaagag    180

aagcatctag cagagatcaa gcggaaactt ggaatcaatt ctctacagga actaaaacag    240

aacattgcca aagggtggca agacgtgaca gcaacatctg cttacaagaa gacatctgaa    300

accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg ctcagtcatc    360

accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga agaaaaggtc    420

gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg agaagtcttg    480

aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa gacacaggag    540

agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca agcgaggtcc    600

aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt ttatttagct    660

ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata tcttcacctc    720

tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga aacaccatta    780

taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc tacagattgt    840

catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt ttgacctttg    900

tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg attcttaact    960

aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg tattttcttt   1020

acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat tgttttggta   1080

taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc atccaattta   1140

ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag agtggaacct   1200

cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt gtttattata   1260

ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa aataacattc   1320

tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat caatgttcag   1380

ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc aatcacatta   1440

ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa gcacaccaag   1500

ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat aactcttgag   1560

gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa tgtgttggaa   1620

actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt cagggctgag   1680

tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc taataactgc   1740

ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac aatgttgtat   1800

ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt aactgccaag   1860

cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag tataaattat   1920

cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata acatgctgcc   1980

attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta tgtgctatca   2040

catgtgaaaa gcttaataaa ttccatctat cagtagtata ggtctcaata tttattatga   2100

gaccagtggt ctggaaacag cttgttgtac cgaatcaact ggagtctatg cttaaaaaaa   2160

aaaaattttt ttttaaccat ccttaaatta ttgcttaatg gtatcatatt aacatattct   2220

aaataagggc tttaaggcac aggctgttga agcattttct cagaggagtg gatctgtaga   2280

agtctgtctt tctatagaaa tattgtgctt actcaagtgt taaattattt tttctatgaa   2340

ctagtctact tcttaaaatt caaacatatt cttttgatca cattgtttct tgagcatcct   2400

gccctgctac taacttttca acaaggcaaa atggagtaaa gtggcaattt ctttagatga   2460

gtgaaatacc ctcaagtctc ttttctgccc aaaaagggaa aagtgataga aatgggggtg   2520

gcaagtgggg tgagtggatg aaggtgggta ttgggggtgg ctgtgaaaga aaataatgga   2580

gaatcacttt tctagacatc tacctatact taatctaaga aacaaagtaa tctactgtaa   2640

agtactctgc cccttgaaag aagtattaaa aagagtgagg atggatttag aaaaaaacat   2700

gaatttagaa atattcaaaa tggtttttgt ggcagattca atattatgaa ttcacagata   2760

tttaaagaat gagaaacata gtaattagta gaaatgccag aaacagttcc tggttcctct   2820

tgtgtttgac actaagaaaa tagcaagagt gtgaaatctc agatacttat gaaatctcac   2880

agatgtaagg actcaagtgt agaagaaaat atccccttct tacaaaaaga aatgtcaatt   2940

tatggagttt gtgggaaata gggcaagaat tcttatgctt atgagagcca agtagtcagt   3000

ggaagagagt agagctcaaa actggattat caccttagca acttagaata gtttgaaata   3060

gaaaaaaagt atttaatttg gatctggatc tgttaagata tgcacagtct attttttgta   3120

tagtattgga aaataaaaat gctataattt gggt                               3154


<210>  5870
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  5870

Met Asp Arg Gly Glu Gln Gly Arg Arg Arg Asn Pro Asp Ser Val Ser 
1               5                   10                  15


Ser Val Ser Ser Lys Arg Glu Ala Ser Ser Arg Asp Gln Ala Glu Thr 
            20                  25                  30


Trp Asn Gln Phe Ser Thr Gly Thr Lys Thr Glu His Cys Gln Arg Val 
        35                  40                  45


Ala Arg Arg Asp Ser Asn Ile Cys Leu Gln Glu Asp Ile 
    50                  55                  60


<210>  5871
<211>  3279
<212>  DNA
<213>  Homo sapiens

<400>  5871
ggacttcgcg ggagtcgccg gcggaggcga ggaggagctc tgcgcggcgc ggcgggcgat     60

ccgagccggg acgggctgca ggcgggggtg ctgcagagga cacgaggcgg cgggctggag    120

acatggaccg cggcgagcaa ggtctgctga gaacagaccc agtccctgag gaaggagaag    180

atgttgctgc cacgatcagt gccacagaga ccctctcgga agaggagcag gaagagctaa    240

gaagagaact tgcaaaggta gaagaagaaa tccagactct gtctcaagtg ttagcagcaa    300

aagagaagca tctagcagag atcaagcgga aacttggaat caattctcta caggaactaa    360

aacagaacat tgccaaaggg tggcaagacg tgacagcaac atctgcttac aagaagacat    420

ctgaaacctt atcccaggct ggacagaagg cctcagctgc tttttcgtct gttggctcag    480

tcatcaccaa aaagctggaa gatgtaaaaa actccccaac ttttaaatca tttgaagaaa    540

aggtcgaaaa cttaaaggca atagggggaa ccaagcctgc tggtggtgat tttggagaag    600

tcttgaattc ggctgcaaat gctagtgcca ccaccacgga gcctcttcca gaaaagacac    660

aggagagcct gtgagattcc tacctttgtt ctgctaccca ctgccagatg ctgcaagcga    720

ggtccaagca catcttgtca acatgcattg ccatgaattt ctaccagatg tgcttttatt    780

tagctttaca tattcctttg accaaatagt ttgtgggtta aacaaaatga aaatatcttc    840

acctctattc ttgggaaaca ccctttagtg tacatttatg ttcctttatt taggaaacac    900

cattataaaa acacttatag taaatgggga cattcactat aatgatctaa gaagctacag    960

attgtcatag ttgttttcct gctttacaaa attgctccag atctggaatg ccagtttgac   1020

ctttgtcttc tataatattt cctttttttc ccctctttga atctctgtat atttgattct   1080

taactaaaat tgttctctta aatattctga atcctggtaa ttaaaagttt gggtgtattt   1140

tctttacctc caaggaaaga actactagct acaaaaaata ttttggaata agcattgttt   1200

tggtataagg tacatatttt ggttgaagac accagactga agtaaacagc tgtgcatcca   1260

atttattata gttttgtaag taacaatatg taatcaaact tctaggtgac ttgagagtgg   1320

aacctcctat atcattattt agcaccgttt gtgacagtaa ccatttcagt gtattgttta   1380

ttataccact tatatcaact tatttttcac caggttaaaa ttttaatttc tacaaaataa   1440

cattctgaat caagcacact gtatgttcag taggttgaac tatgaacact gtcatcaatg   1500

ttcagttcaa aagcctgaaa gtttagatct agaagctggt aaaaatgaca atatcaatca   1560

cattagggga accattgttg tcttcactta atccatttag cactatttaa aataagcaca   1620

ccaagttata tgactaatat aacttgaaaa ttttttatac tgaggggttg gtgataactc   1680

ttgaggatgt aatgcattaa taaaaatcaa ctcatcattt tctacttgtt ttcaatgtgt   1740

tggaaactgt aaaatgatac tgtagaacct gtctcctact ttgaaaactg aatgtcaggg   1800

ctgagtgaat caaagtgtct agacatattt gcatagaggc caaggtattc tattctaata   1860

actgcttact caacactacc accttttcct tatactgtat atgattatgg cctacaatgt   1920

tgtatttgtt atttattaaa ttgtgattgt tttattattg tttatgccaa atgttaactg   1980

ccaagcttgg agtgacctaa agcatttttt aaaagcatgg ctagatttac ttcagtataa   2040

attatcttat gaaaaccaaa ttttaaaagc cacaggtgtt gattgttata aaataacatg   2100

ctgccattct tgattgctag agtttttgtt agtactttgg atgcaattaa aactatgtgc   2160

tatcacatgt gaaaagctta ataaattcca tctatcagta gtataggtct caatatttat   2220

tatgagacca gtggtctgga aacagcttgt tgtaccgaat caactggagt ctatgcttaa   2280

aaaaaaaaaa ttttttttta accatcctta aattattgct taatggtatc atattaacat   2340

attctaaata agggctttaa ggcacaggct gttgaagcat tttctcagag gagtggatct   2400

gtagaagtct gtctttctat agaaatattg tgcttactca agtgttaaat tattttttct   2460

atgaactagt ctacttctta aaattcaaac atattctttt gatcacattg tttcttgagc   2520

atcctgccct gctactaact tttcaacaag gcaaaatgga gtaaagtggc aatttcttta   2580

gatgagtgaa ataccctcaa gtctcttttc tgcccaaaaa gggaaaagtg atagaaatgg   2640

gggtggcaag tggggtgagt ggatgaaggt gggtattggg ggtggctgtg aaagaaaata   2700

atggagaatc acttttctag acatctacct atacttaatc taagaaacaa agtaatctac   2760

tgtaaagtac tctgcccctt gaaagaagta ttaaaaagag tgaggatgga tttagaaaaa   2820

aacatgaatt tagaaatatt caaaatggtt tttgtggcag attcaatatt atgaattcac   2880

agatatttaa agaatgagaa acatagtaat tagtagaaat gccagaaaca gttcctggtt   2940

cctcttgtgt ttgacactaa gaaaatagca agagtgtgaa atctcagata cttatgaaat   3000

ctcacagatg taaggactca agtgtagaag aaaatatccc cttcttacaa aaagaaatgt   3060

caatttatgg agtttgtggg aaatagggca agaattctta tgcttatgag agccaagtag   3120

tcagtggaag agagtagagc tcaaaactgg attatcacct tagcaactta gaatagtttg   3180

aaatagaaaa aaagtattta atttggatct ggatctgtta agatatgcac agtctatttt   3240

ttgtatagta ttggaaaata aaaatgctat aatttgggt                          3279


<210>  5872
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  5872

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu 
    130                 135                 140


Lys Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val 
145                 150                 155                 160


Leu Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro 
                165                 170                 175


Glu Lys Thr Gln Glu Ser Leu 
            180


<210>  5873
<211>  3424
<212>  DNA
<213>  Homo sapiens

<400>  5873
ggttgggtga cgccccagga aagcgctcca ggccgagggc gggcggcgcc gccgcgcccg     60

acgcctctgg gggtggggac ttcgcgggag tcgccggcgg aggcgaggag gagctctgcg    120

cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg ggggtgctgc agaggacacg    180

aggcggcggg ctggagacat ggaccgcggc gagcaaggtc tgctgagaac agacccagtc    240

cctgaggaag gagaagatgt tgctgccacg atcagtgcca cagagaccct ctcggaagag    300

gagcaggaag agctaagaag agaacttgca aaggtagaag aagaaatcca gactctgtct    360

caagtgttag cagcaaaaga gaagcatcta gcagagatca agcggaaact tggaatcaat    420

tctctacagg aactaaaaca gaacattgcc aaagggtggc aagacgtgac agcaacatct    480

gcttacaaga agacatctga aaccttatcc caggctggac agaaggcctc agctgctttt    540

tcgtctgttg gctcagtcat caccaaaaag ctggaagatg taaaattgca agccttttca    600

cattccttta gtatacgttc cattcagcat tcaattagca tgcctgctat gagaaactcc    660

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag    720

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc    780

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct    840

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg    900

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg    960

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1020

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1080

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1140

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1200

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1260

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1320

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1380

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1440

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1500

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1560

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1620

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1680

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   1740

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   1800

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   1860

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   1920

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   1980

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2040

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2100

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2160

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2220

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2280

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2340

cagtagtata ggtctcaata tttattatga gaccagtggt ctggaaacag cttgttgtac   2400

cgaatcaact ggagtctatg cttaaaaaaa aaaaattttt ttttaaccat ccttaaatta   2460

ttgcttaatg gtatcatatt aacatattct aaataagggc tttaaggcac aggctgttga   2520

agcattttct cagaggagtg gatctgtaga agtctgtctt tctatagaaa tattgtgctt   2580

actcaagtgt taaattattt tttctatgaa ctagtctact tcttaaaatt caaacatatt   2640

cttttgatca cattgtttct tgagcatcct gccctgctac taacttttca acaaggcaaa   2700

atggagtaaa gtggcaattt ctttagatga gtgaaatacc ctcaagtctc ttttctgccc   2760

aaaaagggaa aagtgataga aatgggggtg gcaagtgggg tgagtggatg aaggtgggta   2820

ttgggggtgg ctgtgaaaga aaataatgga gaatcacttt tctagacatc tacctatact   2880

taatctaaga aacaaagtaa tctactgtaa agtactctgc cccttgaaag aagtattaaa   2940

aagagtgagg atggatttag aaaaaaacat gaatttagaa atattcaaaa tggtttttgt   3000

ggcagattca atattatgaa ttcacagata tttaaagaat gagaaacata gtaattagta   3060

gaaatgccag aaacagttcc tggttcctct tgtgtttgac actaagaaaa tagcaagagt   3120

gtgaaatctc agatacttat gaaatctcac agatgtaagg actcaagtgt agaagaaaat   3180

atccccttct tacaaaaaga aatgtcaatt tatggagttt gtgggaaata gggcaagaat   3240

tcttatgctt atgagagcca agtagtcagt ggaagagagt agagctcaaa actggattat   3300

caccttagca acttagaata gtttgaaata gaaaaaaagt atttaatttg gatctggatc   3360

tgttaagata tgcacagtct attttttgta tagtattgga aaataaaaat gctataattt   3420

gggt                                                                3424


<210>  5874
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  5874

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Leu Gln Ala Phe Ser His Ser Phe Ser Ile Arg Ser Ile Gln His 
    130                 135                 140


Ser Ile Ser Met Pro Ala Met Arg Asn Ser Pro Thr Phe Lys Ser Phe 
145                 150                 155                 160


Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro Ala 
                165                 170                 175


Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser Ala 
            180                 185                 190


Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
        195                 200                 205


<210>  5875
<211>  1936
<212>  DNA
<213>  Homo sapiens

<400>  5875
attacttatg tctgagactg gccctgttca tggaatcaaa tgcatactct taaaatatta     60

gatcagaaat tgagaatctt acattataaa tacttgtatg tacctgcaca tatatggtac    120

agattatatc tgttcttttg ccgattgaga ataatgttga agaggaatca attatatttt    180

caaactagtt ggattttttt tcagtatttg tatttactat ttgtttttct tttctctcca    240

tagaaactcc ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg    300

gggaaccaag cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag    360

tgccaccacc acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct    420

ttgttctgct acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg    480

cattgccatg aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa    540

atagtttgtg ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt    600

tagtgtacat ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat    660

ggggacattc actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt    720

acaaaattgc tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt    780

ttttcccctc tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat    840

tctgaatcct ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac    900

tagctacaaa aaatattttg gaataagcat tgttttggta taaggtacat attttggttg    960

aagacaccag actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca   1020

atatgtaatc aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac   1080

cgtttgtgac agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt   1140

ttcaccaggt taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg   1200

ttcagtaggt tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta   1260

gatctagaag ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc   1320

acttaatcca tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt   1380

gaaaattttt tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa   1440

atcaactcat cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag   1500

aacctgtctc ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca   1560

tatttgcata gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt   1620

ttccttatac tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg   1680

attgttttat tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat   1740

tttttaaaag catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta   1800

aaagccacag gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt   1860

ttgttagtac tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa   1920

ttccatctat cagtag                                                   1936


<210>  5876
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  5876

Met His Thr Leu Lys Ile Leu Asp Gln Lys Leu Arg Ile Leu His Tyr 
1               5                   10                  15


Lys Tyr Leu Tyr Val Pro Ala His Ile Trp Tyr Arg Leu Tyr Leu Phe 
            20                  25                  30


Phe Cys Arg Leu Arg Ile Met Leu Lys Arg Asn Gln Leu Tyr Phe Gln 
        35                  40                  45


Thr Ser Trp Ile Phe Phe Gln Tyr Leu Tyr Leu Leu Phe Val Phe Leu 
    50                  55                  60


Phe Ser Pro 
65


<210>  5877
<211>  1870
<212>  DNA
<213>  Homo sapiens

<400>  5877
actccttcaa accagtacct ggaaggctca tctaaggtct tctaggccta gcattctaac     60

atcaaatgat catctgatga tcatttaagg ttgttgaaaa attctggttg tgaacttctt    120

tgtcttttta gttcttcatg atcatgcagg attgcaagcc ttttcacatt cctttagaaa    180

ctccccaact tttaaatcat ttgaagaaaa ggtcgaaaac ttaaaggcaa tagggggaac    240

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    300

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    360

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    420

catgaatttc taccagatgt gcttttattt agctttacat attcctttga ccaaatagtt    480

tgtgggttaa acaaaatgaa aatatcttca cctctattct tgggaaacac cctttagtgt    540

acatttatgt tcctttattt aggaaacacc attataaaaa cacttatagt aaatggggac    600

attcactata atgatctaag aagctacaga ttgtcatagt tgttttcctg ctttacaaaa    660

ttgctccaga tctggaatgc cagtttgacc tttgtcttct ataatatttc ctttttttcc    720

cctctttgaa tctctgtata tttgattctt aactaaaatt gttctcttaa atattctgaa    780

tcctggtaat taaaagtttg ggtgtatttt ctttacctcc aaggaaagaa ctactagcta    840

caaaaaatat tttggaataa gcattgtttt ggtataaggt acatattttg gttgaagaca    900

ccagactgaa gtaaacagct gtgcatccaa tttattatag ttttgtaagt aacaatatgt    960

aatcaaactt ctaggtgact tgagagtgga acctcctata tcattattta gcaccgtttg   1020

tgacagtaac catttcagtg tattgtttat tataccactt atatcaactt atttttcacc   1080

aggttaaaat tttaatttct acaaaataac attctgaatc aagcacactg tatgttcagt   1140

aggttgaact atgaacactg tcatcaatgt tcagttcaaa agcctgaaag tttagatcta   1200

gaagctggta aaaatgacaa tatcaatcac attaggggaa ccattgttgt cttcacttaa   1260

tccatttagc actatttaaa ataagcacac caagttatat gactaatata acttgaaaat   1320

tttttatact gaggggttgg tgataactct tgaggatgta atgcattaat aaaaatcaac   1380

tcatcatttt ctacttgttt tcaatgtgtt ggaaactgta aaatgatact gtagaacctg   1440

tctcctactt tgaaaactga atgtcagggc tgagtgaatc aaagtgtcta gacatatttg   1500

catagaggcc aaggtattct attctaataa ctgcttactc aacactacca ccttttcctt   1560

atactgtata tgattatggc ctacaatgtt gtatttgtta tttattaaat tgtgattgtt   1620

ttattattgt ttatgccaaa tgttaactgc caagcttgga gtgacctaaa gcatttttta   1680

aaagcatggc tagatttact tcagtataaa ttatcttatg aaaaccaaat tttaaaagcc   1740

acaggtgttg attgttataa aataacatgc tgccattctt gattgctaga gtttttgtta   1800

gtactttgga tgcaattaaa actatgtgct atcacatgtg aaaagcttaa taaattccat   1860

ctatcagtag                                                          1870


<210>  5878
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  5878

Met Pro Asn Val Asn Cys Gln Ala Trp Ser Asp Leu Lys His Phe Leu 
1               5                   10                  15


Lys Ala Trp Leu Asp Leu Leu Gln Tyr Lys Leu Ser Tyr Glu Asn Gln 
            20                  25                  30


Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr Lys Ile Thr Cys Cys His 
        35                  40                  45


Ser 



<210>  5879
<211>  1858
<212>  DNA
<213>  Homo sapiens

<400>  5879
agagtgaggg agggcactcc ttcaaaccag tacctggaag gctcatctaa ggtcttctag     60

gcctagcatt ctaacatcaa atgatcatct gatgatcatt taaggttgtt gaaaaattct    120

ggttgtgaac ttctttgtct ttttagttct tcatgatcat gcaggaaact ccccaacttt    180

taaatcattt gaagaaaagg tcgaaaactt aaaggcaata gggggaacca agcctgctgg    240

tggtgatttt ggagaagtct tgaattcggc tgcaaatgct agtgccacca ccacggagcc    300

tcttccagaa aagacacagg agagcctgtg agattcctac ctttgttctg ctacccactg    360

ccagatgctg caagcgaggt ccaagcacat cttgtcaaca tgcattgcca tgaatttcta    420

ccagatgtgc ttttatttag ctttacatat tcctttgacc aaatagtttg tgggttaaac    480

aaaatgaaaa tatcttcacc tctattcttg ggaaacaccc tttagtgtac atttatgttc    540

ctttatttag gaaacaccat tataaaaaca cttatagtaa atggggacat tcactataat    600

gatctaagaa gctacagatt gtcatagttg ttttcctgct ttacaaaatt gctccagatc    660

tggaatgcca gtttgacctt tgtcttctat aatatttcct ttttttcccc tctttgaatc    720

tctgtatatt tgattcttaa ctaaaattgt tctcttaaat attctgaatc ctggtaatta    780

aaagtttggg tgtattttct ttacctccaa ggaaagaact actagctaca aaaaatattt    840

tggaataagc attgttttgg tataaggtac atattttggt tgaagacacc agactgaagt    900

aaacagctgt gcatccaatt tattatagtt ttgtaagtaa caatatgtaa tcaaacttct    960

aggtgacttg agagtggaac ctcctatatc attatttagc accgtttgtg acagtaacca   1020

tttcagtgta ttgtttatta taccacttat atcaacttat ttttcaccag gttaaaattt   1080

taatttctac aaaataacat tctgaatcaa gcacactgta tgttcagtag gttgaactat   1140

gaacactgtc atcaatgttc agttcaaaag cctgaaagtt tagatctaga agctggtaaa   1200

aatgacaata tcaatcacat taggggaacc attgttgtct tcacttaatc catttagcac   1260

tatttaaaat aagcacacca agttatatga ctaatataac ttgaaaattt tttatactga   1320

ggggttggtg ataactcttg aggatgtaat gcattaataa aaatcaactc atcattttct   1380

acttgttttc aatgtgttgg aaactgtaaa atgatactgt agaacctgtc tcctactttg   1440

aaaactgaat gtcagggctg agtgaatcaa agtgtctaga catatttgca tagaggccaa   1500

ggtattctat tctaataact gcttactcaa cactaccacc ttttccttat actgtatatg   1560

attatggcct acaatgttgt atttgttatt tattaaattg tgattgtttt attattgttt   1620

atgccaaatg ttaactgcca agcttggagt gacctaaagc attttttaaa agcatggcta   1680

gatttacttc agtataaatt atcttatgaa aaccaaattt taaaagccac aggtgttgat   1740

tgttataaaa taacatgctg ccattcttga ttgctagagt ttttgttagt actttggatg   1800

caattaaaac tatgtgctat cacatgtgaa aagcttaata aattccatct atcagtag     1858


<210>  5880
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  5880

Met Pro Asn Val Asn Cys Gln Ala Trp Ser Asp Leu Lys His Phe Leu 
1               5                   10                  15


Lys Ala Trp Leu Asp Leu Leu Gln Tyr Lys Leu Ser Tyr Glu Asn Gln 
            20                  25                  30


Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr Lys Ile Thr Cys Cys His 
        35                  40                  45


Ser 



<210>  5881
<211>  2026
<212>  DNA
<213>  Homo sapiens

<400>  5881
ctttctggct ggactagggc actgcagaag attgtgcctg agcttagggt tgagcatacg     60

aagatgtggt gatgccgctc tgctggttat gaaggatttt agaagttctg aaaaatgttt    120

tctctttttg agagttctcc agcaggtggt gaccactgca cttgaaacaa ttgatattag    180

aaaagatgag ctgacccttc ttttgctctg tgtgtttata atttaatata gttacaagaa    240

gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg    300

ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga    360

agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg    420

agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa    480

gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca    540

agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt    600

ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata    660

tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga    720

aacaccatta taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc    780

tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt    840

ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg    900

attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg    960

tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat   1020

tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc   1080

atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag   1140

agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt   1200

gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa   1260

aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat   1320

caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc   1380

aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa   1440

gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat   1500

aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa   1560

tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt   1620

cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc   1680

taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac   1740

aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt   1800

aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag   1860

tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata   1920

acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta   1980

tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtag                  2026


<210>  5882
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  5882

Met Pro Asn Val Asn Cys Gln Ala Trp Ser Asp Leu Lys His Phe Leu 
1               5                   10                  15


Lys Ala Trp Leu Asp Leu Leu Gln Tyr Lys Leu Ser Tyr Glu Asn Gln 
            20                  25                  30


Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr Lys Ile Thr Cys Cys His 
        35                  40                  45


Ser 



<210>  5883
<211>  2124
<212>  DNA
<213>  Homo sapiens

<400>  5883
ggagcttaaa tagggatttt acttagattt tgcactttaa aaaatggttt aaatccccaa     60

ccaggtctgc tgagaacaga cccagtccct gaggaaggag aagatgttgc tgccacgatc    120

agtgccacag agaccctctc ggaagaggag caggaagagc taagaagaga acttgcaaag    180

gtagaagaag aaatccagac tctgtctcaa gtgttagcag caaaagagaa gcatctagca    240

gagatcaagc ggaaacttgg aatcaattct ctacaggaac taaaacagaa cattgccaaa    300

gggtggcaag acgtgacagc aacatctgct tacaagaaga catctgaaac cttatcccag    360

gctggacaga aggcctcagc tgctttttcg tctgttggct cagtcatcac caaaaagctg    420

gaagatgtaa aaaactcccc aacttttaaa tcatttgaag aaaaggtcga aaacttaaag    480

gcaatagggg gaaccaagcc tgctggtggt gattttggag aagtcttgaa ttcggctgca    540

aatgctagtg ccaccaccac ggagcctctt ccagaaaaga cacaggagag cctgtgagat    600

tcctaccttt gttctgctac ccactgccag atgctgcaag cgaggtccaa gcacatcttg    660

tcaacatgca ttgccatgaa tttctaccag atgtgctttt atttagcttt acatattcct    720

ttgaccaaat agtttgtggg ttaaacaaaa tgaaaatatc ttcacctcta ttcttgggaa    780

acacccttta gtgtacattt atgttccttt atttaggaaa caccattata aaaacactta    840

tagtaaatgg ggacattcac tataatgatc taagaagcta cagattgtca tagttgtttt    900

cctgctttac aaaattgctc cagatctgga atgccagttt gacctttgtc ttctataata    960

tttccttttt ttcccctctt tgaatctctg tatatttgat tcttaactaa aattgttctc   1020

ttaaatattc tgaatcctgg taattaaaag tttgggtgta ttttctttac ctccaaggaa   1080

agaactacta gctacaaaaa atattttgga ataagcattg ttttggtata aggtacatat   1140

tttggttgaa gacaccagac tgaagtaaac agctgtgcat ccaatttatt atagttttgt   1200

aagtaacaat atgtaatcaa acttctaggt gacttgagag tggaacctcc tatatcatta   1260

tttagcaccg tttgtgacag taaccatttc agtgtattgt ttattatacc acttatatca   1320

acttattttt caccaggtta aaattttaat ttctacaaaa taacattctg aatcaagcac   1380

actgtatgtt cagtaggttg aactatgaac actgtcatca atgttcagtt caaaagcctg   1440

aaagtttaga tctagaagct ggtaaaaatg acaatatcaa tcacattagg ggaaccattg   1500

ttgtcttcac ttaatccatt tagcactatt taaaataagc acaccaagtt atatgactaa   1560

tataacttga aaatttttta tactgagggg ttggtgataa ctcttgagga tgtaatgcat   1620

taataaaaat caactcatca ttttctactt gttttcaatg tgttggaaac tgtaaaatga   1680

tactgtagaa cctgtctcct actttgaaaa ctgaatgtca gggctgagtg aatcaaagtg   1740

tctagacata tttgcataga ggccaaggta ttctattcta ataactgctt actcaacact   1800

accacctttt ccttatactg tatatgatta tggcctacaa tgttgtattt gttatttatt   1860

aaattgtgat tgttttatta ttgtttatgc caaatgttaa ctgccaagct tggagtgacc   1920

taaagcattt tttaaaagca tggctagatt tacttcagta taaattatct tatgaaaacc   1980

aaattttaaa agccacaggt gttgattgtt ataaaataac atgctgccat tcttgattgc   2040

tagagttttt gttagtactt tggatgcaat taaaactatg tgctatcaca tgtgaaaagc   2100

ttaataaatt ccatctatca gtag                                          2124


<210>  5884
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  5884

Met Pro Asn Val Asn Cys Gln Ala Trp Ser Asp Leu Lys His Phe Leu 
1               5                   10                  15


Lys Ala Trp Leu Asp Leu Leu Gln Tyr Lys Leu Ser Tyr Glu Asn Gln 
            20                  25                  30


Ile Leu Lys Ala Thr Gly Val Asp Cys Tyr Lys Ile Thr Cys Cys His 
        35                  40                  45


Ser 



<210>  5885
<211>  2576
<212>  DNA
<213>  Homo sapiens

<400>  5885
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta    900

aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg    960

gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc   1020

ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc   1080

agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc   1140

agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa   1200

aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct   1260

ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc actataatga   1320

tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg   1380

gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc   1440

tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa   1500

agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg   1560

gaataagcat tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa   1620

acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag   1680

gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt   1740

tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta   1800

atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga   1860

acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa   1920

tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta   1980

tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg   2040

ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac   2100

ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc ctactttgaa   2160

aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata gaggccaagg   2220

tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac tgtatatgat   2280

tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat tattgtttat   2340

gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag catggctaga   2400

tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag gtgttgattg   2460

ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac tttggatgca   2520

attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat cagtag       2576


<210>  5886
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  5886

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Asn Ser Pro Thr Phe Lys Ser 
                165                 170                 175


Phe Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro 
            180                 185                 190


Ala Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser 
        195                 200                 205


Ala Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
    210                 215                 220


<210>  5887
<211>  2645
<212>  DNA
<213>  Homo sapiens

<400>  5887
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaattgcaa gccttttcac    900

attcctttag tatacgttcc attcagcatt caattagcat gcctgctatg agaaactccc    960

caacttttaa atcatttgaa gaaaaggtcg aaaacttaaa ggcaataggg ggaaccaagc   1020

ctgctggtgg tgattttgga gaagtcttga attcggctgc aaatgctagt gccaccacca   1080

cggagcctct tccagaaaag acacaggaga gcctgtgaga ttcctacctt tgttctgcta   1140

cccactgcca gatgctgcaa gcgaggtcca agcacatctt gtcaacatgc attgccatga   1200

atttctacca gatgtgcttt tatttagctt tacatattcc tttgaccaaa tagtttgtgg   1260

gttaaacaaa atgaaaatat cttcacctct attcttggga aacacccttt agtgtacatt   1320

tatgttcctt tatttaggaa acaccattat aaaaacactt atagtaaatg gggacattca   1380

ctataatgat ctaagaagct acagattgtc atagttgttt tcctgcttta caaaattgct   1440

ccagatctgg aatgccagtt tgacctttgt cttctataat atttcctttt tttcccctct   1500

ttgaatctct gtatatttga ttcttaacta aaattgttct cttaaatatt ctgaatcctg   1560

gtaattaaaa gtttgggtgt attttcttta cctccaagga aagaactact agctacaaaa   1620

aatattttgg aataagcatt gttttggtat aaggtacata ttttggttga agacaccaga   1680

ctgaagtaaa cagctgtgca tccaatttat tatagttttg taagtaacaa tatgtaatca   1740

aacttctagg tgacttgaga gtggaacctc ctatatcatt atttagcacc gtttgtgaca   1800

gtaaccattt cagtgtattg tttattatac cacttatatc aacttatttt tcaccaggtt   1860

aaaattttaa tttctacaaa ataacattct gaatcaagca cactgtatgt tcagtaggtt   1920

gaactatgaa cactgtcatc aatgttcagt tcaaaagcct gaaagtttag atctagaagc   1980

tggtaaaaat gacaatatca atcacattag gggaaccatt gttgtcttca cttaatccat   2040

ttagcactat ttaaaataag cacaccaagt tatatgacta atataacttg aaaatttttt   2100

atactgaggg gttggtgata actcttgagg atgtaatgca ttaataaaaa tcaactcatc   2160

attttctact tgttttcaat gtgttggaaa ctgtaaaatg atactgtaga acctgtctcc   2220

tactttgaaa actgaatgtc agggctgagt gaatcaaagt gtctagacat atttgcatag   2280

aggccaaggt attctattct aataactgct tactcaacac taccaccttt tccttatact   2340

gtatatgatt atggcctaca atgttgtatt tgttatttat taaattgtga ttgttttatt   2400

attgtttatg ccaaatgtta actgccaagc ttggagtgac ctaaagcatt ttttaaaagc   2460

atggctagat ttacttcagt ataaattatc ttatgaaaac caaattttaa aagccacagg   2520

tgttgattgt tataaaataa catgctgcca ttcttgattg ctagagtttt tgttagtact   2580

ttggatgcaa ttaaaactat gtgctatcac atgtgaaaag cttaataaat tccatctatc   2640

agtag                                                               2645


<210>  5888
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  5888

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Leu Gln Ala Phe Ser His Ser 
                165                 170                 175


Phe Ser Ile Arg Ser Ile Gln His Ser Ile Ser Met Pro Ala Met Arg 
            180                 185                 190


Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu Lys 
        195                 200                 205


Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val Leu 
    210                 215                 220


Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro Glu 
225                 230                 235                 240


Lys Thr Gln Glu Ser Leu 
                245


<210>  5889
<211>  2646
<212>  DNA
<213>  Homo sapiens

<400>  5889
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cgaggagcaa gcttctagca gcagaaaccg aactgctctg tcttctgtat tgagagccat    840

ctgcagagct gttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca    900

gctgcttttt cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc    960

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag   1020

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc   1080

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct   1140

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg   1200

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg   1260

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1320

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1380

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1440

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1500

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1560

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1620

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1680

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1740

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1800

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1860

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1920

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1980

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   2040

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   2100

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   2160

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   2220

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   2280

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2340

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2400

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2460

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2520

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2580

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2640

cagtag                                                              2646


<210>  5890
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  5890

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Arg Ser Lys Leu Leu Ala Ala Glu Thr 
    130                 135                 140


Glu Leu Leu Cys Leu Leu Tyr 
145                 150


<210>  5891
<211>  2076
<212>  DNA
<213>  Homo sapiens

<400>  5891
gggagtcgcc ggcggaggcg aggaggagct ctgcgcggcg cggcgggcga tccgagccgg     60

gacgggctgc aggcgggggt gctgcagagg acacgaggcg gcgggctgga gacatggacc    120

gcggcgagca aggtagaaga agaaatccag actctgtctc aagtgttagc agcaaaagag    180

aagcatctag cagagatcaa gcggaaactt ggaatcaatt ctctacagga actaaaacag    240

aacattgcca aagggtggca agacgtgaca gcaacatctg cttacaagaa gacatctgaa    300

accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg ctcagtcatc    360

accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga agaaaaggtc    420

gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg agaagtcttg    480

aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa gacacaggag    540

agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca agcgaggtcc    600

aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt ttatttagct    660

ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata tcttcacctc    720

tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga aacaccatta    780

taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc tacagattgt    840

catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt ttgacctttg    900

tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg attcttaact    960

aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg tattttcttt   1020

acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat tgttttggta   1080

taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc atccaattta   1140

ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag agtggaacct   1200

cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt gtttattata   1260

ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa aataacattc   1320

tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat caatgttcag   1380

ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc aatcacatta   1440

ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa gcacaccaag   1500

ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat aactcttgag   1560

gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttcaa tgtgttggaa   1620

actgtaaaat gatactgtag aacctgtctc ctactttgaa aactgaatgt cagggctgag   1680

tgaatcaaag tgtctagaca tatttgcata gaggccaagg tattctattc taataactgc   1740

ttactcaaca ctaccacctt ttccttatac tgtatatgat tatggcctac aatgttgtat   1800

ttgttattta ttaaattgtg attgttttat tattgtttat gccaaatgtt aactgccaag   1860

cttggagtga cctaaagcat tttttaaaag catggctaga tttacttcag tataaattat   1920

cttatgaaaa ccaaatttta aaagccacag gtgttgattg ttataaaata acatgctgcc   1980

attcttgatt gctagagttt ttgttagtac tttggatgca attaaaacta tgtgctatca   2040

catgtgaaaa gcttaataaa ttccatctat cagtag                             2076


<210>  5892
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  5892

Met Asp Arg Gly Glu Gln Gly Arg Arg Arg Asn Pro Asp Ser Val Ser 
1               5                   10                  15


Ser Val Ser Ser Lys Arg Glu Ala Ser Ser Arg Asp Gln Ala Glu Thr 
            20                  25                  30


Trp Asn Gln Phe Ser Thr Gly Thr Lys Thr Glu His Cys Gln Arg Val 
        35                  40                  45


Ala Arg Arg Asp Ser Asn Ile Cys Leu Gln Glu Asp Ile 
    50                  55                  60


<210>  5893
<211>  2201
<212>  DNA
<213>  Homo sapiens

<400>  5893
ggacttcgcg ggagtcgccg gcggaggcga ggaggagctc tgcgcggcgc ggcgggcgat     60

ccgagccggg acgggctgca ggcgggggtg ctgcagagga cacgaggcgg cgggctggag    120

acatggaccg cggcgagcaa ggtctgctga gaacagaccc agtccctgag gaaggagaag    180

atgttgctgc cacgatcagt gccacagaga ccctctcgga agaggagcag gaagagctaa    240

gaagagaact tgcaaaggta gaagaagaaa tccagactct gtctcaagtg ttagcagcaa    300

aagagaagca tctagcagag atcaagcgga aacttggaat caattctcta caggaactaa    360

aacagaacat tgccaaaggg tggcaagacg tgacagcaac atctgcttac aagaagacat    420

ctgaaacctt atcccaggct ggacagaagg cctcagctgc tttttcgtct gttggctcag    480

tcatcaccaa aaagctggaa gatgtaaaaa actccccaac ttttaaatca tttgaagaaa    540

aggtcgaaaa cttaaaggca atagggggaa ccaagcctgc tggtggtgat tttggagaag    600

tcttgaattc ggctgcaaat gctagtgcca ccaccacgga gcctcttcca gaaaagacac    660

aggagagcct gtgagattcc tacctttgtt ctgctaccca ctgccagatg ctgcaagcga    720

ggtccaagca catcttgtca acatgcattg ccatgaattt ctaccagatg tgcttttatt    780

tagctttaca tattcctttg accaaatagt ttgtgggtta aacaaaatga aaatatcttc    840

acctctattc ttgggaaaca ccctttagtg tacatttatg ttcctttatt taggaaacac    900

cattataaaa acacttatag taaatgggga cattcactat aatgatctaa gaagctacag    960

attgtcatag ttgttttcct gctttacaaa attgctccag atctggaatg ccagtttgac   1020

ctttgtcttc tataatattt cctttttttc ccctctttga atctctgtat atttgattct   1080

taactaaaat tgttctctta aatattctga atcctggtaa ttaaaagttt gggtgtattt   1140

tctttacctc caaggaaaga actactagct acaaaaaata ttttggaata agcattgttt   1200

tggtataagg tacatatttt ggttgaagac accagactga agtaaacagc tgtgcatcca   1260

atttattata gttttgtaag taacaatatg taatcaaact tctaggtgac ttgagagtgg   1320

aacctcctat atcattattt agcaccgttt gtgacagtaa ccatttcagt gtattgttta   1380

ttataccact tatatcaact tatttttcac caggttaaaa ttttaatttc tacaaaataa   1440

cattctgaat caagcacact gtatgttcag taggttgaac tatgaacact gtcatcaatg   1500

ttcagttcaa aagcctgaaa gtttagatct agaagctggt aaaaatgaca atatcaatca   1560

cattagggga accattgttg tcttcactta atccatttag cactatttaa aataagcaca   1620

ccaagttata tgactaatat aacttgaaaa ttttttatac tgaggggttg gtgataactc   1680

ttgaggatgt aatgcattaa taaaaatcaa ctcatcattt tctacttgtt ttcaatgtgt   1740

tggaaactgt aaaatgatac tgtagaacct gtctcctact ttgaaaactg aatgtcaggg   1800

ctgagtgaat caaagtgtct agacatattt gcatagaggc caaggtattc tattctaata   1860

actgcttact caacactacc accttttcct tatactgtat atgattatgg cctacaatgt   1920

tgtatttgtt atttattaaa ttgtgattgt tttattattg tttatgccaa atgttaactg   1980

ccaagcttgg agtgacctaa agcatttttt aaaagcatgg ctagatttac ttcagtataa   2040

attatcttat gaaaaccaaa ttttaaaagc cacaggtgtt gattgttata aaataacatg   2100

ctgccattct tgattgctag agtttttgtt agtactttgg atgcaattaa aactatgtgc   2160

tatcacatgt gaaaagctta ataaattcca tctatcagta g                       2201


<210>  5894
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  5894

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu 
    130                 135                 140


Lys Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val 
145                 150                 155                 160


Leu Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro 
                165                 170                 175


Glu Lys Thr Gln Glu Ser Leu 
            180


<210>  5895
<211>  2346
<212>  DNA
<213>  Homo sapiens

<400>  5895
ggttgggtga cgccccagga aagcgctcca ggccgagggc gggcggcgcc gccgcgcccg     60

acgcctctgg gggtggggac ttcgcgggag tcgccggcgg aggcgaggag gagctctgcg    120

cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg ggggtgctgc agaggacacg    180

aggcggcggg ctggagacat ggaccgcggc gagcaaggtc tgctgagaac agacccagtc    240

cctgaggaag gagaagatgt tgctgccacg atcagtgcca cagagaccct ctcggaagag    300

gagcaggaag agctaagaag agaacttgca aaggtagaag aagaaatcca gactctgtct    360

caagtgttag cagcaaaaga gaagcatcta gcagagatca agcggaaact tggaatcaat    420

tctctacagg aactaaaaca gaacattgcc aaagggtggc aagacgtgac agcaacatct    480

gcttacaaga agacatctga aaccttatcc caggctggac agaaggcctc agctgctttt    540

tcgtctgttg gctcagtcat caccaaaaag ctggaagatg taaaattgca agccttttca    600

cattccttta gtatacgttc cattcagcat tcaattagca tgcctgctat gagaaactcc    660

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag    720

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc    780

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct    840

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg    900

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg    960

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1020

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1080

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1140

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1200

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1260

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1320

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1380

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1440

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1500

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1560

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1620

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1680

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   1740

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   1800

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   1860

cattttctac ttgttttcaa tgtgttggaa actgtaaaat gatactgtag aacctgtctc   1920

ctactttgaa aactgaatgt cagggctgag tgaatcaaag tgtctagaca tatttgcata   1980

gaggccaagg tattctattc taataactgc ttactcaaca ctaccacctt ttccttatac   2040

tgtatatgat tatggcctac aatgttgtat ttgttattta ttaaattgtg attgttttat   2100

tattgtttat gccaaatgtt aactgccaag cttggagtga cctaaagcat tttttaaaag   2160

catggctaga tttacttcag tataaattat cttatgaaaa ccaaatttta aaagccacag   2220

gtgttgattg ttataaaata acatgctgcc attcttgatt gctagagttt ttgttagtac   2280

tttggatgca attaaaacta tgtgctatca catgtgaaaa gcttaataaa ttccatctat   2340

cagtag                                                              2346


<210>  5896
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  5896

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Leu Gln Ala Phe Ser His Ser Phe Ser Ile Arg Ser Ile Gln His 
    130                 135                 140


Ser Ile Ser Met Pro Ala Met Arg Asn Ser Pro Thr Phe Lys Ser Phe 
145                 150                 155                 160


Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro Ala 
                165                 170                 175


Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser Ala 
            180                 185                 190


Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
        195                 200                 205


<210>  5897
<211>  1468
<212>  DNA
<213>  Homo sapiens

<400>  5897
attacttatg tctgagactg gccctgttca tggaatcaaa tgcatactct taaaatatta     60

gatcagaaat tgagaatctt acattataaa tacttgtatg tacctgcaca tatatggtac    120

agattatatc tgttcttttg ccgattgaga ataatgttga agaggaatca attatatttt    180

caaactagtt ggattttttt tcagtatttg tatttactat ttgtttttct tttctctcca    240

tagaaactcc ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg    300

gggaaccaag cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag    360

tgccaccacc acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct    420

ttgttctgct acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg    480

cattgccatg aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa    540

atagtttgtg ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt    600

tagtgtacat ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat    660

ggggacattc actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt    720

acaaaattgc tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt    780

ttttcccctc tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat    840

tctgaatcct ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac    900

tagctacaaa aaatattttg gaataagcat tgttttggta taaggtacat attttggttg    960

aagacaccag actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca   1020

atatgtaatc aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac   1080

cgtttgtgac agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt   1140

ttcaccaggt taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg   1200

ttcagtaggt tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta   1260

gatctagaag ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc   1320

acttaatcca tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt   1380

gaaaattttt tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa   1440

atcaactcat cattttctac ttgttttc                                      1468


<210>  5898
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  5898

Met His Thr Leu Lys Ile Leu Asp Gln Lys Leu Arg Ile Leu His Tyr 
1               5                   10                  15


Lys Tyr Leu Tyr Val Pro Ala His Ile Trp Tyr Arg Leu Tyr Leu Phe 
            20                  25                  30


Phe Cys Arg Leu Arg Ile Met Leu Lys Arg Asn Gln Leu Tyr Phe Gln 
        35                  40                  45


Thr Ser Trp Ile Phe Phe Gln Tyr Leu Tyr Leu Leu Phe Val Phe Leu 
    50                  55                  60


Phe Ser Pro 
65


<210>  5899
<211>  1402
<212>  DNA
<213>  Homo sapiens

<400>  5899
actccttcaa accagtacct ggaaggctca tctaaggtct tctaggccta gcattctaac     60

atcaaatgat catctgatga tcatttaagg ttgttgaaaa attctggttg tgaacttctt    120

tgtcttttta gttcttcatg atcatgcagg attgcaagcc ttttcacatt cctttagaaa    180

ctccccaact tttaaatcat ttgaagaaaa ggtcgaaaac ttaaaggcaa tagggggaac    240

caagcctgct ggtggtgatt ttggagaagt cttgaattcg gctgcaaatg ctagtgccac    300

caccacggag cctcttccag aaaagacaca ggagagcctg tgagattcct acctttgttc    360

tgctacccac tgccagatgc tgcaagcgag gtccaagcac atcttgtcaa catgcattgc    420

catgaatttc taccagatgt gcttttattt agctttacat attcctttga ccaaatagtt    480

tgtgggttaa acaaaatgaa aatatcttca cctctattct tgggaaacac cctttagtgt    540

acatttatgt tcctttattt aggaaacacc attataaaaa cacttatagt aaatggggac    600

attcactata atgatctaag aagctacaga ttgtcatagt tgttttcctg ctttacaaaa    660

ttgctccaga tctggaatgc cagtttgacc tttgtcttct ataatatttc ctttttttcc    720

cctctttgaa tctctgtata tttgattctt aactaaaatt gttctcttaa atattctgaa    780

tcctggtaat taaaagtttg ggtgtatttt ctttacctcc aaggaaagaa ctactagcta    840

caaaaaatat tttggaataa gcattgtttt ggtataaggt acatattttg gttgaagaca    900

ccagactgaa gtaaacagct gtgcatccaa tttattatag ttttgtaagt aacaatatgt    960

aatcaaactt ctaggtgact tgagagtgga acctcctata tcattattta gcaccgtttg   1020

tgacagtaac catttcagtg tattgtttat tataccactt atatcaactt atttttcacc   1080

aggttaaaat tttaatttct acaaaataac attctgaatc aagcacactg tatgttcagt   1140

aggttgaact atgaacactg tcatcaatgt tcagttcaaa agcctgaaag tttagatcta   1200

gaagctggta aaaatgacaa tatcaatcac attaggggaa ccattgttgt cttcacttaa   1260

tccatttagc actatttaaa ataagcacac caagttatat gactaatata acttgaaaat   1320

tttttatact gaggggttgg tgataactct tgaggatgta atgcattaat aaaaatcaac   1380

tcatcatttt ctacttgttt tc                                            1402


<210>  5900
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  5900

Met Leu Val Pro Pro Pro Arg Ser Leu Phe Gln Lys Arg His Arg Arg 
1               5                   10                  15


Ala Cys Glu Ile Pro Thr Phe Val Leu Leu Pro Thr Ala Arg Cys Cys 
            20                  25                  30


Lys Arg Gly Pro Ser Thr Ser Cys Gln His Ala Leu Pro 
        35                  40                  45


<210>  5901
<211>  1390
<212>  DNA
<213>  Homo sapiens

<400>  5901
agagtgaggg agggcactcc ttcaaaccag tacctggaag gctcatctaa ggtcttctag     60

gcctagcatt ctaacatcaa atgatcatct gatgatcatt taaggttgtt gaaaaattct    120

ggttgtgaac ttctttgtct ttttagttct tcatgatcat gcaggaaact ccccaacttt    180

taaatcattt gaagaaaagg tcgaaaactt aaaggcaata gggggaacca agcctgctgg    240

tggtgatttt ggagaagtct tgaattcggc tgcaaatgct agtgccacca ccacggagcc    300

tcttccagaa aagacacagg agagcctgtg agattcctac ctttgttctg ctacccactg    360

ccagatgctg caagcgaggt ccaagcacat cttgtcaaca tgcattgcca tgaatttcta    420

ccagatgtgc ttttatttag ctttacatat tcctttgacc aaatagtttg tgggttaaac    480

aaaatgaaaa tatcttcacc tctattcttg ggaaacaccc tttagtgtac atttatgttc    540

ctttatttag gaaacaccat tataaaaaca cttatagtaa atggggacat tcactataat    600

gatctaagaa gctacagatt gtcatagttg ttttcctgct ttacaaaatt gctccagatc    660

tggaatgcca gtttgacctt tgtcttctat aatatttcct ttttttcccc tctttgaatc    720

tctgtatatt tgattcttaa ctaaaattgt tctcttaaat attctgaatc ctggtaatta    780

aaagtttggg tgtattttct ttacctccaa ggaaagaact actagctaca aaaaatattt    840

tggaataagc attgttttgg tataaggtac atattttggt tgaagacacc agactgaagt    900

aaacagctgt gcatccaatt tattatagtt ttgtaagtaa caatatgtaa tcaaacttct    960

aggtgacttg agagtggaac ctcctatatc attatttagc accgtttgtg acagtaacca   1020

tttcagtgta ttgtttatta taccacttat atcaacttat ttttcaccag gttaaaattt   1080

taatttctac aaaataacat tctgaatcaa gcacactgta tgttcagtag gttgaactat   1140

gaacactgtc atcaatgttc agttcaaaag cctgaaagtt tagatctaga agctggtaaa   1200

aatgacaata tcaatcacat taggggaacc attgttgtct tcacttaatc catttagcac   1260

tatttaaaat aagcacacca agttatatga ctaatataac ttgaaaattt tttatactga   1320

ggggttggtg ataactcttg aggatgtaat gcattaataa aaatcaactc atcattttct   1380

acttgttttc                                                          1390


<210>  5902
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  5902

Met Leu Val Pro Pro Pro Arg Ser Leu Phe Gln Lys Arg His Arg Arg 
1               5                   10                  15


Ala Cys Glu Ile Pro Thr Phe Val Leu Leu Pro Thr Ala Arg Cys Cys 
            20                  25                  30


Lys Arg Gly Pro Ser Thr Ser Cys Gln His Ala Leu Pro 
        35                  40                  45


<210>  5903
<211>  1558
<212>  DNA
<213>  Homo sapiens

<400>  5903
ctttctggct ggactagggc actgcagaag attgtgcctg agcttagggt tgagcatacg     60

aagatgtggt gatgccgctc tgctggttat gaaggatttt agaagttctg aaaaatgttt    120

tctctttttg agagttctcc agcaggtggt gaccactgca cttgaaacaa ttgatattag    180

aaaagatgag ctgacccttc ttttgctctg tgtgtttata atttaatata gttacaagaa    240

gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg    300

ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga    360

agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg    420

agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa    480

gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca    540

agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt    600

ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata    660

tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga    720

aacaccatta taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc    780

tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt    840

ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg    900

attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg    960

tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat   1020

tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc   1080

atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag   1140

agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt   1200

gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa   1260

aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat   1320

caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc   1380

aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa   1440

gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat   1500

aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttc     1558


<210>  5904
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  5904

Met Lys Asp Phe Arg Ser Ser Glu Lys Cys Phe Leu Phe Leu Arg Val 
1               5                   10                  15


Leu Gln Gln Val Val Thr Thr Ala Leu Glu Thr Ile Asp Ile Arg Lys 
            20                  25                  30


Asp Glu Leu Thr Leu Leu Leu Leu Cys Val Phe Ile Ile 
        35                  40                  45


<210>  5905
<211>  1656
<212>  DNA
<213>  Homo sapiens

<400>  5905
ggagcttaaa tagggatttt acttagattt tgcactttaa aaaatggttt aaatccccaa     60

ccaggtctgc tgagaacaga cccagtccct gaggaaggag aagatgttgc tgccacgatc    120

agtgccacag agaccctctc ggaagaggag caggaagagc taagaagaga acttgcaaag    180

gtagaagaag aaatccagac tctgtctcaa gtgttagcag caaaagagaa gcatctagca    240

gagatcaagc ggaaacttgg aatcaattct ctacaggaac taaaacagaa cattgccaaa    300

gggtggcaag acgtgacagc aacatctgct tacaagaaga catctgaaac cttatcccag    360

gctggacaga aggcctcagc tgctttttcg tctgttggct cagtcatcac caaaaagctg    420

gaagatgtaa aaaactcccc aacttttaaa tcatttgaag aaaaggtcga aaacttaaag    480

gcaatagggg gaaccaagcc tgctggtggt gattttggag aagtcttgaa ttcggctgca    540

aatgctagtg ccaccaccac ggagcctctt ccagaaaaga cacaggagag cctgtgagat    600

tcctaccttt gttctgctac ccactgccag atgctgcaag cgaggtccaa gcacatcttg    660

tcaacatgca ttgccatgaa tttctaccag atgtgctttt atttagcttt acatattcct    720

ttgaccaaat agtttgtggg ttaaacaaaa tgaaaatatc ttcacctcta ttcttgggaa    780

acacccttta gtgtacattt atgttccttt atttaggaaa caccattata aaaacactta    840

tagtaaatgg ggacattcac tataatgatc taagaagcta cagattgtca tagttgtttt    900

cctgctttac aaaattgctc cagatctgga atgccagttt gacctttgtc ttctataata    960

tttccttttt ttcccctctt tgaatctctg tatatttgat tcttaactaa aattgttctc   1020

ttaaatattc tgaatcctgg taattaaaag tttgggtgta ttttctttac ctccaaggaa   1080

agaactacta gctacaaaaa atattttgga ataagcattg ttttggtata aggtacatat   1140

tttggttgaa gacaccagac tgaagtaaac agctgtgcat ccaatttatt atagttttgt   1200

aagtaacaat atgtaatcaa acttctaggt gacttgagag tggaacctcc tatatcatta   1260

tttagcaccg tttgtgacag taaccatttc agtgtattgt ttattatacc acttatatca   1320

acttattttt caccaggtta aaattttaat ttctacaaaa taacattctg aatcaagcac   1380

actgtatgtt cagtaggttg aactatgaac actgtcatca atgttcagtt caaaagcctg   1440

aaagtttaga tctagaagct ggtaaaaatg acaatatcaa tcacattagg ggaaccattg   1500

ttgtcttcac ttaatccatt tagcactatt taaaataagc acaccaagtt atatgactaa   1560

tataacttga aaatttttta tactgagggg ttggtgataa ctcttgagga tgtaatgcat   1620

taataaaaat caactcatca ttttctactt gttttc                             1656


<210>  5906
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  5906

Met Leu Val Pro Pro Pro Arg Ser Leu Phe Gln Lys Arg His Arg Arg 
1               5                   10                  15


Ala Cys Glu Ile Pro Thr Phe Val Leu Leu Pro Thr Ala Arg Cys Cys 
            20                  25                  30


Lys Arg Gly Pro Ser Thr Ser Cys Gln His Ala Leu Pro 
        35                  40                  45


<210>  5907
<211>  2108
<212>  DNA
<213>  Homo sapiens

<400>  5907
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaaaactcc ccaactttta    900

aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag cctgctggtg    960

gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc acggagcctc   1020

ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct acccactgcc   1080

agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg aatttctacc   1140

agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg ggttaaacaa   1200

aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat ttatgttcct   1260

ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc actataatga   1320

tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc tccagatctg   1380

gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc tttgaatctc   1440

tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct ggtaattaaa   1500

agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa aaatattttg   1560

gaataagcat tgttttggta taaggtacat attttggttg aagacaccag actgaagtaa   1620

acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc aaacttctag   1680

gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac agtaaccatt   1740

tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt taaaatttta   1800

atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt tgaactatga   1860

acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa   1920

tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca tttagcacta   1980

tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt tatactgagg   2040

ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat cattttctac   2100

ttgttttc                                                            2108


<210>  5908
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  5908

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Asn Ser Pro Thr Phe Lys Ser 
                165                 170                 175


Phe Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro 
            180                 185                 190


Ala Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser 
        195                 200                 205


Ala Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
    210                 215                 220


<210>  5909
<211>  2177
<212>  DNA
<213>  Homo sapiens

<400>  5909
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttggtct gctgagaaca gacccagtcc    540

ctgaggaagg agaagatgtt gctgccacga tcagtgccac agagaccctc tcggaagagg    600

agcaggaaga gctaagaaga gaacttgcaa aggtagaaga agaaatccag actctgtctc    660

aagtgttagc agcaaaagag aagcatctag cagagatcaa gcggaaactt ggaatcaatt    720

ctctacagga actaaaacag aacattgcca aagggtggca agacgtgaca gcaacatctg    780

cttacaagaa gacatctgaa accttatccc aggctggaca gaaggcctca gctgcttttt    840

cgtctgttgg ctcagtcatc accaaaaagc tggaagatgt aaaattgcaa gccttttcac    900

attcctttag tatacgttcc attcagcatt caattagcat gcctgctatg agaaactccc    960

caacttttaa atcatttgaa gaaaaggtcg aaaacttaaa ggcaataggg ggaaccaagc   1020

ctgctggtgg tgattttgga gaagtcttga attcggctgc aaatgctagt gccaccacca   1080

cggagcctct tccagaaaag acacaggaga gcctgtgaga ttcctacctt tgttctgcta   1140

cccactgcca gatgctgcaa gcgaggtcca agcacatctt gtcaacatgc attgccatga   1200

atttctacca gatgtgcttt tatttagctt tacatattcc tttgaccaaa tagtttgtgg   1260

gttaaacaaa atgaaaatat cttcacctct attcttggga aacacccttt agtgtacatt   1320

tatgttcctt tatttaggaa acaccattat aaaaacactt atagtaaatg gggacattca   1380

ctataatgat ctaagaagct acagattgtc atagttgttt tcctgcttta caaaattgct   1440

ccagatctgg aatgccagtt tgacctttgt cttctataat atttcctttt tttcccctct   1500

ttgaatctct gtatatttga ttcttaacta aaattgttct cttaaatatt ctgaatcctg   1560

gtaattaaaa gtttgggtgt attttcttta cctccaagga aagaactact agctacaaaa   1620

aatattttgg aataagcatt gttttggtat aaggtacata ttttggttga agacaccaga   1680

ctgaagtaaa cagctgtgca tccaatttat tatagttttg taagtaacaa tatgtaatca   1740

aacttctagg tgacttgaga gtggaacctc ctatatcatt atttagcacc gtttgtgaca   1800

gtaaccattt cagtgtattg tttattatac cacttatatc aacttatttt tcaccaggtt   1860

aaaattttaa tttctacaaa ataacattct gaatcaagca cactgtatgt tcagtaggtt   1920

gaactatgaa cactgtcatc aatgttcagt tcaaaagcct gaaagtttag atctagaagc   1980

tggtaaaaat gacaatatca atcacattag gggaaccatt gttgtcttca cttaatccat   2040

ttagcactat ttaaaataag cacaccaagt tatatgacta atataacttg aaaatttttt   2100

atactgaggg gttggtgata actcttgagg atgtaatgca ttaataaaaa tcaactcatc   2160

attttctact tgttttc                                                  2177


<210>  5910
<211>  246
<212>  PRT
<213>  Homo sapiens

<400>  5910

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Gly Leu 
        35                  40                  45


Leu Arg Thr Asp Pro Val Pro Glu Glu Gly Glu Asp Val Ala Ala Thr 
    50                  55                  60


Ile Ser Ala Thr Glu Thr Leu Ser Glu Glu Glu Gln Glu Glu Leu Arg 
65                  70                  75                  80


Arg Glu Leu Ala Lys Val Glu Glu Glu Ile Gln Thr Leu Ser Gln Val 
                85                  90                  95


Leu Ala Ala Lys Glu Lys His Leu Ala Glu Ile Lys Arg Lys Leu Gly 
            100                 105                 110


Ile Asn Ser Leu Gln Glu Leu Lys Gln Asn Ile Ala Lys Gly Trp Gln 
        115                 120                 125


Asp Val Thr Ala Thr Ser Ala Tyr Lys Lys Thr Ser Glu Thr Leu Ser 
    130                 135                 140


Gln Ala Gly Gln Lys Ala Ser Ala Ala Phe Ser Ser Val Gly Ser Val 
145                 150                 155                 160


Ile Thr Lys Lys Leu Glu Asp Val Lys Leu Gln Ala Phe Ser His Ser 
                165                 170                 175


Phe Ser Ile Arg Ser Ile Gln His Ser Ile Ser Met Pro Ala Met Arg 
            180                 185                 190


Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu Lys 
        195                 200                 205


Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val Leu 
    210                 215                 220


Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro Glu 
225                 230                 235                 240


Lys Thr Gln Glu Ser Leu 
                245


<210>  5911
<211>  1608
<212>  DNA
<213>  Homo sapiens

<400>  5911
gggagtcgcc ggcggaggcg aggaggagct ctgcgcggcg cggcgggcga tccgagccgg     60

gacgggctgc aggcgggggt gctgcagagg acacgaggcg gcgggctgga gacatggacc    120

gcggcgagca aggtagaaga agaaatccag actctgtctc aagtgttagc agcaaaagag    180

aagcatctag cagagatcaa gcggaaactt ggaatcaatt ctctacagga actaaaacag    240

aacattgcca aagggtggca agacgtgaca gcaacatctg cttacaagaa gacatctgaa    300

accttatccc aggctggaca gaaggcctca gctgcttttt cgtctgttgg ctcagtcatc    360

accaaaaagc tggaagatgt aaaaaactcc ccaactttta aatcatttga agaaaaggtc    420

gaaaacttaa aggcaatagg gggaaccaag cctgctggtg gtgattttgg agaagtcttg    480

aattcggctg caaatgctag tgccaccacc acggagcctc ttccagaaaa gacacaggag    540

agcctgtgag attcctacct ttgttctgct acccactgcc agatgctgca agcgaggtcc    600

aagcacatct tgtcaacatg cattgccatg aatttctacc agatgtgctt ttatttagct    660

ttacatattc ctttgaccaa atagtttgtg ggttaaacaa aatgaaaata tcttcacctc    720

tattcttggg aaacaccctt tagtgtacat ttatgttcct ttatttagga aacaccatta    780

taaaaacact tatagtaaat ggggacattc actataatga tctaagaagc tacagattgt    840

catagttgtt ttcctgcttt acaaaattgc tccagatctg gaatgccagt ttgacctttg    900

tcttctataa tatttccttt ttttcccctc tttgaatctc tgtatatttg attcttaact    960

aaaattgttc tcttaaatat tctgaatcct ggtaattaaa agtttgggtg tattttcttt   1020

acctccaagg aaagaactac tagctacaaa aaatattttg gaataagcat tgttttggta   1080

taaggtacat attttggttg aagacaccag actgaagtaa acagctgtgc atccaattta   1140

ttatagtttt gtaagtaaca atatgtaatc aaacttctag gtgacttgag agtggaacct   1200

cctatatcat tatttagcac cgtttgtgac agtaaccatt tcagtgtatt gtttattata   1260

ccacttatat caacttattt ttcaccaggt taaaatttta atttctacaa aataacattc   1320

tgaatcaagc acactgtatg ttcagtaggt tgaactatga acactgtcat caatgttcag   1380

ttcaaaagcc tgaaagttta gatctagaag ctggtaaaaa tgacaatatc aatcacatta   1440

ggggaaccat tgttgtcttc acttaatcca tttagcacta tttaaaataa gcacaccaag   1500

ttatatgact aatataactt gaaaattttt tatactgagg ggttggtgat aactcttgag   1560

gatgtaatgc attaataaaa atcaactcat cattttctac ttgttttc                1608


<210>  5912
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  5912

Met Asp Arg Gly Glu Gln Gly Arg Arg Arg Asn Pro Asp Ser Val Ser 
1               5                   10                  15


Ser Val Ser Ser Lys Arg Glu Ala Ser Ser Arg Asp Gln Ala Glu Thr 
            20                  25                  30


Trp Asn Gln Phe Ser Thr Gly Thr Lys Thr Glu His Cys Gln Arg Val 
        35                  40                  45


Ala Arg Arg Asp Ser Asn Ile Cys Leu Gln Glu Asp Ile 
    50                  55                  60


<210>  5913
<211>  1733
<212>  DNA
<213>  Homo sapiens

<400>  5913
ggacttcgcg ggagtcgccg gcggaggcga ggaggagctc tgcgcggcgc ggcgggcgat     60

ccgagccggg acgggctgca ggcgggggtg ctgcagagga cacgaggcgg cgggctggag    120

acatggaccg cggcgagcaa ggtctgctga gaacagaccc agtccctgag gaaggagaag    180

atgttgctgc cacgatcagt gccacagaga ccctctcgga agaggagcag gaagagctaa    240

gaagagaact tgcaaaggta gaagaagaaa tccagactct gtctcaagtg ttagcagcaa    300

aagagaagca tctagcagag atcaagcgga aacttggaat caattctcta caggaactaa    360

aacagaacat tgccaaaggg tggcaagacg tgacagcaac atctgcttac aagaagacat    420

ctgaaacctt atcccaggct ggacagaagg cctcagctgc tttttcgtct gttggctcag    480

tcatcaccaa aaagctggaa gatgtaaaaa actccccaac ttttaaatca tttgaagaaa    540

aggtcgaaaa cttaaaggca atagggggaa ccaagcctgc tggtggtgat tttggagaag    600

tcttgaattc ggctgcaaat gctagtgcca ccaccacgga gcctcttcca gaaaagacac    660

aggagagcct gtgagattcc tacctttgtt ctgctaccca ctgccagatg ctgcaagcga    720

ggtccaagca catcttgtca acatgcattg ccatgaattt ctaccagatg tgcttttatt    780

tagctttaca tattcctttg accaaatagt ttgtgggtta aacaaaatga aaatatcttc    840

acctctattc ttgggaaaca ccctttagtg tacatttatg ttcctttatt taggaaacac    900

cattataaaa acacttatag taaatgggga cattcactat aatgatctaa gaagctacag    960

attgtcatag ttgttttcct gctttacaaa attgctccag atctggaatg ccagtttgac   1020

ctttgtcttc tataatattt cctttttttc ccctctttga atctctgtat atttgattct   1080

taactaaaat tgttctctta aatattctga atcctggtaa ttaaaagttt gggtgtattt   1140

tctttacctc caaggaaaga actactagct acaaaaaata ttttggaata agcattgttt   1200

tggtataagg tacatatttt ggttgaagac accagactga agtaaacagc tgtgcatcca   1260

atttattata gttttgtaag taacaatatg taatcaaact tctaggtgac ttgagagtgg   1320

aacctcctat atcattattt agcaccgttt gtgacagtaa ccatttcagt gtattgttta   1380

ttataccact tatatcaact tatttttcac caggttaaaa ttttaatttc tacaaaataa   1440

cattctgaat caagcacact gtatgttcag taggttgaac tatgaacact gtcatcaatg   1500

ttcagttcaa aagcctgaaa gtttagatct agaagctggt aaaaatgaca atatcaatca   1560

cattagggga accattgttg tcttcactta atccatttag cactatttaa aataagcaca   1620

ccaagttata tgactaatat aacttgaaaa ttttttatac tgaggggttg gtgataactc   1680

ttgaggatgt aatgcattaa taaaaatcaa ctcatcattt tctacttgtt ttc          1733


<210>  5914
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  5914

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Asn Ser Pro Thr Phe Lys Ser Phe Glu Glu Lys Val Glu Asn Leu 
    130                 135                 140


Lys Ala Ile Gly Gly Thr Lys Pro Ala Gly Gly Asp Phe Gly Glu Val 
145                 150                 155                 160


Leu Asn Ser Ala Ala Asn Ala Ser Ala Thr Thr Thr Glu Pro Leu Pro 
                165                 170                 175


Glu Lys Thr Gln Glu Ser Leu 
            180


<210>  5915
<211>  1878
<212>  DNA
<213>  Homo sapiens

<400>  5915
ggttgggtga cgccccagga aagcgctcca ggccgagggc gggcggcgcc gccgcgcccg     60

acgcctctgg gggtggggac ttcgcgggag tcgccggcgg aggcgaggag gagctctgcg    120

cggcgcggcg ggcgatccga gccgggacgg gctgcaggcg ggggtgctgc agaggacacg    180

aggcggcggg ctggagacat ggaccgcggc gagcaaggtc tgctgagaac agacccagtc    240

cctgaggaag gagaagatgt tgctgccacg atcagtgcca cagagaccct ctcggaagag    300

gagcaggaag agctaagaag agaacttgca aaggtagaag aagaaatcca gactctgtct    360

caagtgttag cagcaaaaga gaagcatcta gcagagatca agcggaaact tggaatcaat    420

tctctacagg aactaaaaca gaacattgcc aaagggtggc aagacgtgac agcaacatct    480

gcttacaaga agacatctga aaccttatcc caggctggac agaaggcctc agctgctttt    540

tcgtctgttg gctcagtcat caccaaaaag ctggaagatg taaaattgca agccttttca    600

cattccttta gtatacgttc cattcagcat tcaattagca tgcctgctat gagaaactcc    660

ccaactttta aatcatttga agaaaaggtc gaaaacttaa aggcaatagg gggaaccaag    720

cctgctggtg gtgattttgg agaagtcttg aattcggctg caaatgctag tgccaccacc    780

acggagcctc ttccagaaaa gacacaggag agcctgtgag attcctacct ttgttctgct    840

acccactgcc agatgctgca agcgaggtcc aagcacatct tgtcaacatg cattgccatg    900

aatttctacc agatgtgctt ttatttagct ttacatattc ctttgaccaa atagtttgtg    960

ggttaaacaa aatgaaaata tcttcacctc tattcttggg aaacaccctt tagtgtacat   1020

ttatgttcct ttatttagga aacaccatta taaaaacact tatagtaaat ggggacattc   1080

actataatga tctaagaagc tacagattgt catagttgtt ttcctgcttt acaaaattgc   1140

tccagatctg gaatgccagt ttgacctttg tcttctataa tatttccttt ttttcccctc   1200

tttgaatctc tgtatatttg attcttaact aaaattgttc tcttaaatat tctgaatcct   1260

ggtaattaaa agtttgggtg tattttcttt acctccaagg aaagaactac tagctacaaa   1320

aaatattttg gaataagcat tgttttggta taaggtacat attttggttg aagacaccag   1380

actgaagtaa acagctgtgc atccaattta ttatagtttt gtaagtaaca atatgtaatc   1440

aaacttctag gtgacttgag agtggaacct cctatatcat tatttagcac cgtttgtgac   1500

agtaaccatt tcagtgtatt gtttattata ccacttatat caacttattt ttcaccaggt   1560

taaaatttta atttctacaa aataacattc tgaatcaagc acactgtatg ttcagtaggt   1620

tgaactatga acactgtcat caatgttcag ttcaaaagcc tgaaagttta gatctagaag   1680

ctggtaaaaa tgacaatatc aatcacatta ggggaaccat tgttgtcttc acttaatcca   1740

tttagcacta tttaaaataa gcacaccaag ttatatgact aatataactt gaaaattttt   1800

tatactgagg ggttggtgat aactcttgag gatgtaatgc attaataaaa atcaactcat   1860

cattttctac ttgttttc                                                 1878


<210>  5916
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  5916

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Leu Gln Ala Phe Ser His Ser Phe Ser Ile Arg Ser Ile Gln His 
    130                 135                 140


Ser Ile Ser Met Pro Ala Met Arg Asn Ser Pro Thr Phe Lys Ser Phe 
145                 150                 155                 160


Glu Glu Lys Val Glu Asn Leu Lys Ala Ile Gly Gly Thr Lys Pro Ala 
                165                 170                 175


Gly Gly Asp Phe Gly Glu Val Leu Asn Ser Ala Ala Asn Ala Ser Ala 
            180                 185                 190


Thr Thr Thr Glu Pro Leu Pro Glu Lys Thr Gln Glu Ser Leu 
        195                 200                 205


<210>  5917
<211>  587
<212>  DNA
<213>  Homo sapiens

<400>  5917
gatccgagcc gggacgggct gcaggcgggg gtgctgcaga ggacacgagg cggcgggctg     60

gagacatgga ccgcggcgag caagcttttt atttcatctg gaatttctgg cttgaattag    120

ggaaagattt atcttttctc cactcatata aaatgtctgc tgagaacaga cccagtccct    180

gaggaaggag aagatgttgc tgccacgatc agtgccacag agaccctctc ggaagaggag    240

caggaagagc taagaagaga acttgcaaag gtagaagaag aaatccagac tctgtctcaa    300

gtgttagcag caaaagagaa gcatctagca gagatcaagc ggaaacttgg aatcaattct    360

ctacaggaac taaaacagaa cattgccaaa gggtggcaag acgtgacagc aacatctgct    420

tacaagaaga catctgaaac cttatcccag gctggacaga aggcctcagc tgctttttcg    480

tctgttggct cagtcatcac caaaaagctg gaagatgtaa aattgcaagc cttttcacat    540

tcctttagta tacgttccat tcagcattca attagcatgc ctgctat                  587


<210>  5918
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  5918

Met Asp Arg Gly Glu Gln Ala Phe Tyr Phe Ile Trp Asn Phe Trp Leu 
1               5                   10                  15


Glu Leu Gly Lys Asp Leu Ser Phe Leu His Ser Tyr Lys Met Ser Ala 
            20                  25                  30


Glu Asn Arg Pro Ser Pro 
        35


<210>  5919
<211>  564
<212>  DNA
<213>  Homo sapiens

<400>  5919
ggaggcgagg aggagctctg cgcggcgcgg cgggcgatcc gagccgggac gggctgcagg     60

cgggggtgct gcagaggaca cgaggcggcg ggctggagac atggaccgcg gcgagcaagg    120

tctgctgaga acagacccag tccctgagga aggagaagat gttgctgcca cgatcagtgc    180

cacagagacc ctctcggaag aggagcagga agagctaaga agagaacttg caaaggtaga    240

agaagaaatc cagactctgt ctcaagtgtt agcagcaaaa gagaagcatc tagcagagat    300

caagcggaaa cttggaatca attctctaca ggaactaaaa cagaacattg ccaaagggtg    360

gcaagacgtg acagcaacat ctgcttacaa gaagacatct gaaaccttat cccaggctgg    420

acagaaggcc tcagctgctt tttcgtctgt tggctcagtc atcaccaaaa agctggaaga    480

tgtaaagtat gtcctcattt ttccttgctc attaagtagc tgacgcaaat taaaatgtta    540

ttgttgttgc atctgtttcc tgac                                           564


<210>  5920
<211>  140
<212>  PRT
<213>  Homo sapiens

<400>  5920

Met Asp Arg Gly Glu Gln Gly Leu Leu Arg Thr Asp Pro Val Pro Glu 
1               5                   10                  15


Glu Gly Glu Asp Val Ala Ala Thr Ile Ser Ala Thr Glu Thr Leu Ser 
            20                  25                  30


Glu Glu Glu Gln Glu Glu Leu Arg Arg Glu Leu Ala Lys Val Glu Glu 
        35                  40                  45


Glu Ile Gln Thr Leu Ser Gln Val Leu Ala Ala Lys Glu Lys His Leu 
    50                  55                  60


Ala Glu Ile Lys Arg Lys Leu Gly Ile Asn Ser Leu Gln Glu Leu Lys 
65                  70                  75                  80


Gln Asn Ile Ala Lys Gly Trp Gln Asp Val Thr Ala Thr Ser Ala Tyr 
                85                  90                  95


Lys Lys Thr Ser Glu Thr Leu Ser Gln Ala Gly Gln Lys Ala Ser Ala 
            100                 105                 110


Ala Phe Ser Ser Val Gly Ser Val Ile Thr Lys Lys Leu Glu Asp Val 
        115                 120                 125


Lys Tyr Val Leu Ile Phe Pro Cys Ser Leu Ser Ser 
    130                 135                 140


<210>  5921
<211>  1920
<212>  DNA
<213>  Homo sapiens

<400>  5921
agtgtctgat gtttgcctga actgtttgta cctctgggcc atattgcaga accctgccct     60

tctttgttga ctgaggaaag ctcgctccct gcccaggttt ttcattgttg atcgaaatta    120

acaccaggtg gtgaatagag cccctcctaa ggttgctcag gataaatcat ttattaaata    180

ggtctgctta tcaggagggg cgtgaaggct cccaaaagga aatgctggca cctgggccca    240

gaagccaggg cctctaactc ctggggttga tttcttcagt gaagttgcac cctacaaagg    300

gaatatggcc aaagcggcac tcaactgaag gctgatatca ggcgattaga cagccatgca    360

ttctgcgttt gtctggaatg gattgtagag agatggactt atatgaggac taccagtccc    420

cgtttgattt tgatgcagga gtgaacaaaa gctatctcta cttgtctcct agtggaaatt    480

catctccacc cggatcacct actcttcaga aatttgactg caccttttaa ttttaatgat    540

aatgatttgc tgccacctac gggctaatgt ggaaagagca gaacatgtca ttaccaactt    600

tcttagatgc tgaatataaa atctcaaggt catcctggca gacttgaagc caactggaca    660

acccgtcatc ctcttttctg agagatttat tttccttgat agcctagccg catacttgaa    720

tagaaccaga atccccttgg attctttttg gaattgggca gtatacataa agcattgtgt    780

tagcagtcag atactgtatt tctccccttg tttgagtaga tttgcaaaac agtgtgtatc    840

aaaaaagcat gaaagagtct ttgctattta agtaatggtt tggtacctga gttttgcttg    900

ttttgttttg gagatctgtt gtagttggag aacctgggag ttctgtacaa aacattaaaa    960

ataaaataac gtttaacagg tagctctgtt atggttctta ctgtgttgcc ttatatgatt   1020

gttacttgaa tgcttgactc tcagtttcaa tctcatacaa ctttcttcac ataatctgac   1080

atagagggta gatttacaag cacacacaga tgctgggaaa tggtttctga cagtacatag   1140

tacagcacgt tgttcacggt gtggtttggc aggagttgga gtaagaggtg ccaatgccag   1200

ctagcaggag acgggtccag taagggctac ctgccaacct caggggtcac actttgcttt   1260

gaaaacagta aggaatcacc aaaggatttt aagctgaaga gtgatacagt cagatttcta   1320

ttatagaaat attatttggg cagtctgttc acaaatattt tagaggaaga cctgcggaag   1380

caattatgca ttgagctttt ctacttgctg attgtaccta ttaaatattt tatattcagt   1440

caagagctta atcatatttt ttgccagtcc gatttgtggt ttttgaattt tttgtgttac   1500

ttttatgcct ttaacagttc tgtgctttcc aggtaggcac tattttggtg ctgccatgct   1560

gatgattatt attataatta ttaactgcta ttaatcagtg agtgtacagt agagcctgta   1620

ccaagtgcct ttgtaacttg tacaccatgt acataagcat catctcattg actcatgtaa   1680

ttctctaatg cttgctgcga cgctggctgc ttgttccaca gtgtggttat tctccttcct   1740

ttttcttctg tgtctgctcc ctggcgcctt gcattgggca ggatgccaca ttgctgctgt   1800

ggctgaactg gcagttctca gaaatggtcc tggggggtag cagggaacaa ctgcagtggc   1860

tgtgatgctc actggcagga agagcaggca gaggagtaaa ccttcccctg gtttctttgc   1920


<210>  5922
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  5922

Met Asp Cys Arg Glu Met Asp Leu Tyr Glu Asp Tyr Gln Ser Pro Phe 
1               5                   10                  15


Asp Phe Asp Ala Gly Val Asn Lys Ser Tyr Leu Tyr Leu Ser Pro Ser 
            20                  25                  30


Gly Asn Ser Ser Pro Pro Gly Ser Pro Thr Leu Gln Lys Phe Asp Cys 
        35                  40                  45


Thr Phe 
    50


<210>  5923
<211>  5149
<212>  DNA
<213>  Homo sapiens

<400>  5923
aagcaccaac ctatcaagga gaagtcccac ccagtctgcc ctgtgcctat ataaaggcga     60

caagtggcgg ccgcagcact cattgaagcc gccagttggg agaggagcag agccaggccg    120

gtgctcccga aggcagcaag atgttgcgag ccacagctcc ctgctggttc ccccctggat    180

acccagaagc taagaaggtg gccgaggagg cggccctgga ggcaagccgc catttgggag    240

gggagcagag ccaggccggt gctcccgaag gcagcaagat gttgcgagcc acagctccct    300

gctggttccg ccctggatac ccagaagcta agaaggtggc caaggaggcg gccccggagg    360

caagccgcca tttgggagcg gagcagagcc cggccggtgc tcccgaaggc agcaagatgt    420

tgcgagccac agctccctgc tggttcccac ctggataccc agaagctaag aaggtggccg    480

aggaggcggc cctcgaggct ccagaattcc cactgccctc tcatcagcct gcccagagct    540

tcgggctctg ggtgccccag atgcacaagc aggcctcagc atttgtggac atccaggcgg    600

agccccagaa caggggtccg gcggtgcccc cagcgtggcc caagatggtg acggagtcgt    660

gctacttccc tgcgcagagg ggatcggcct gccgcttgcc agccgcccca aggctgacag    720

agaggccctc gggagtccgc atctcagccc ccaggaagag gaagacgatc gcccactctt    780

ccagcccttg cttggtcaca ggttacacag atgccaagag aacccgggtg gccagcagca    840

gccaacgctc ccgtggctcc aaggtcggca gacagccagg gaagactcgc aacaggtcag    900

ggatggcatg caagaccacc gccaccacca gctctaagcg aatcgtccgt cgtccatcct    960

taccgagttt gagtttgaag aaacccatta tcctccgaag ctctgggtgc caagtcccca   1020

ccgtcctccg ccgaggctat ctccaactgt tcaccgaaga gtgtctcaag ttctgcgcct   1080

ccaagcagga ggccgaggag aaggcgctga acgaggagaa ggtggcctac gactgcagcc   1140

ccaacaagaa caggtacctg aacgtggtcc tgaacaccct caagagactg aagggcctga   1200

cccccagctc catgcccggc ctcagcaggg ccgccctgta cagccgcctc caggagttcc   1260

tgctcaccca ggaccagctc aaggagaacg gctacccctt cccgcacccc gagcggcccg   1320

gaggcgccgt cctcttcact ggccagggga aggggcccgg cgactcctcc tgcagggtct   1380

gctgccgttg tggcaccgag tacctggtgt cctcctcggg ccgctgtgta cgcgaccagt   1440

tgtgttatta tcactggggg cgggtccgct cgagccaggt ggctggaggc cgggttagcc   1500

agtacacctg ctgtgcagct gctcctggct ctgtgggctg ccaggtggca aagcagcacg   1560

tgcgggacgg ccgcaaggag agcctcgatg gcttcgtgga gaccttcaag aaagagttgt   1620

ccagagacgc ttatccagga atctacgcct tggactgtga gatgtgctac accacgcatg   1680

gcctggagct gacccgcgtc accgtggtgg acgccgacat gcgagtggtg tacgacacct   1740

tcgtcaagcc cgacaacgag atcgtggact acaacaccag gttttccgga gtcaccgagg   1800

ccgacgtcgc caagacgagc atcacgttgc cccaagtcca agccatcctg ctgagctttt   1860

tcagcgccca aaccatcctc atcgggcaca gcctggagag cgacctgctg gccctgaagc   1920

tcatccacaa caccgtggtg gacacggccg tgctcttccc gcactacctg ggtttcccct   1980

acaagcgctc cctcaggaat ctcgcggccg actacctggc acagatcatc caggacagcc   2040

aggacggcca caactccagc gaggacgcaa acgcctgcct gcagctggtg atgtggaagg   2100

tccgacagcg cgcccagatc cagccacgcc accggtccgc ctctcccgcc gccctggcct   2160

gtccttagcc ccaggcctct tccaaaaccg ccatcagtcc cgagagctca ccctgcccac   2220

ctcgccgcaa agcgaaagaa actggagcag ccggcggcag gagagggcaa aaagccaaga   2280

gtaaccccaa ccccccactc ccggtccccc ggaatccctg ccgcggcccc tcgggcctgt   2340

ccacatccct ctgcccctcc cagacctctg tccttccacc aatcgcctcc cgcagccccg   2400

agccgccact cccagtcccc cgagtccctg ccgcgcgccc tcgcgcctgt ccacatccct   2460

ctgcccatcc gagacctctg tccttacacc actagccacc ccacgtggga cttccatggc   2520

ttctgagtac aaggccagcc ccccggccca ccagctttcg gaatgcctgc ttacctcttt   2580

ttctgtacta tttacggttg ttgcttccta aacatgaact acgtttaggc tgatatttca   2640

gacaatgaaa cctttgagtg cccgtagcgg gaagatctcg gttgctgagt gcagggaagg   2700

aggatgtaat tccatcatat atactctctg tgcctaccgc atttggaacc atgcgagtga   2760

tacctattta taaaataaaa taaaccaagc aaaagtacga acttagcaac actatattga   2820

gttaatagaa cggtatcttg tatttcttct gtccaggtat acttataaat gcctgcaggg   2880

atttcaccac ctcagggtgg agggactgaa tgcttgtgag ggaattagga tggtggaata   2940

ttggtgttac cagggaaggg ggcgggatgt ttgaaaatgc tatgtttact cgttcttggg   3000

ttccaataaa ggagaaacag ggcacaggag tcggaaggac tagtggcaat agtgatgaaa   3060

ggacctcctt atcatgctgg caatgttaat tacccaggtg taggaagcca tacactgagg   3120

cggaagatcg caagtcagag tggccggcag gcacaacctc ctggcacacc agaggcaggt   3180

cttcaatacc cactggtttc cccaacaggc tgcgtaaggg accctgagcc acagtgagtt   3240

ggtcaaatgc tcctgacagt gtggagaaac caacagacaa aacgtgggtg caaaagtgat   3300

gagaccccac actttacact cgtggtgaca atgaagctat taagtaacag cttctcaacc   3360

tatgctgttt cctgttggat gcacataatc catttgcact gcagacaatt ttaggatgtg   3420

gtttacagta aggtggatgg taccttatgg caaaaatctc tcagaaattt atgtgtggtt   3480

ttaaagtcat tccagtccta gcacgttgtg cttttcagag acgccatagc tgtttttccc   3540

tttgtaatat caaagcagta atatgttctc tggaggcctg ttgggtgaat ttaatggaat   3600

caagttaagt aggtgccaga accattgctg ttttccctcc atagccctgc cacccactgt   3660

aaaaaggttg atgagattac ttaatgattt ccaattaagt tgtatttcca aatatcatga   3720

tttccatttt aatgtagttg gtatggagct ctgtgagtgt gtgcttcttt tattatggat   3780

cacgttcagc ttctttttat ttgcctccta gtcataatag taaaactcta ctcctctact   3840

ccgaggagtc cctaccaccc atctcatcac tttccagccc agcactcttc atgctcattc   3900

atttaaagca ttcaacattg tgtaaatgaa tcttggaagg caaaagctac tgaatttagc   3960

gaatttgtgg aggcattgcc acaaatcagc caggtgaagt ttcacacaat cgaagactgc   4020

acaactccta gaaggcagca ctatgctgca aacccagacg gccactcttc tcacccctcg   4080

tccgtttgct gttctggata atgaggttca aaagtcacct aggcaactgc caaaatagct   4140

gaaatggaga aagggcttca ggctggtgac tagcagaggt ccacctgacc cccgtaagct   4200

gctgaacaag tagggctgcc agaaatgtcc cactagggaa tttggtagag acgaagacat   4260

gctcaccgga caagggttcc tcccaggata cgcccgagcg gaagaagcgg gctctgagcc   4320

acgccctttc accctcctct accccgccct gggctggtga aggtgcgcgc caggatgtgg   4380

actaccgagc cctgaagaaa taagtccttc cactttgacc ccatggagga ttgcctgtga   4440

ggaacttaaa cgagtctacc agtgtctaga cacgggggca ggtctgtccg gcacagcagc   4500

tccctcaagg aggagaagag tgaggagaaa ggaaactcaa gtctcaccat tctgtcctgg   4560

gagagaagag gaggatctca tctctcatct gtccaaacaa gtcaaggaga ctttctctca   4620

tctttccaag caaggcaagg ctgtgttgaa cattgcccaa ctcctgggag agaagtgggt   4680

gcggtccact tcctgtcctc aatttgtccg cagcggagga gtgcacagag caaggaaagg   4740

caacccaatc ctaggtagcc caattccagt agccattata ggactgccct gcagggacag   4800

ttacttaact caggaaaagc aacctagctc caagtttagc aaccgggagc tccagttgat   4860

tccattagcg caccccctga ggcattccca agctggagtc tggtggaaga tgaggctcag   4920

ggtgattgga ctgaagcacc aacctatcaa ggagaagtcc cacccagtct gccctgtgcg   4980

tatataaagg cgacgcgtgg cggccgcagc actcattgaa gccgccagtt gggagaggag   5040

cagagccagg ccggtgctcc cgaaggcagc aagatgttgc gagccacagc tccctgctgg   5100

ttcccacctg gatacccaga aactaagaag gtggccgagg aggcggccc               5149


<210>  5924
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  5924

Met Ala Ser Glu Tyr Lys Ala Ser Pro Pro Ala His Gln Leu Ser Glu 
1               5                   10                  15


Cys Leu Leu Thr Ser Phe Ser Val Leu Phe Thr Val Val Ala Ser 
            20                  25                  30


<210>  5925
<211>  5402
<212>  DNA
<213>  Homo sapiens

<400>  5925
aagcaccaac ctatcaagga gaagtcccac ccagtctgcc ctgtgcctat ataaaggcga     60

caagtggcgg ccgcagcact cattgaagcc gccagttggg agaggagcag agccaggccg    120

gtgctcccga aggcagcaag atgttgcgag ccacagctcc ctgctggttc ccccctggat    180

acccagaagc taagaaggtg gccgaggagg cggccctgga ggcaagccgc catttgggag    240

gggagcagag ccaggccggt gctcccgaag gcagcaagat gttgcgagcc acagctccct    300

gctggttccg ccctggatac ccagaagcta agaaggtggc caaggaggcg gccccggagg    360

caagccgcca tttgggagcg gagcagagcc cggccggtgc tcccgaaggc agcaagatgt    420

tgcgagccac agctccctgc tggttcccac ctggataccc agaagctaag aaggtggccg    480

aggaggcggc cctcgaggct ccagaattcc cactgccctc tcatcagcct gcccagagct    540

tcgggctctg ggtgccccag atgcacaagc aggcctcagc atttgtggac atccaggcgg    600

agccccagaa caggggtccg gcggtgcccc cagcgtggcc caagatggtg acggagtcgt    660

gctacttccc tgcgcagagg ggatcggcct gccgcttgcc agccgcccca aggctgacag    720

agaggccctc gggagtccgc atctcagccc ccaggaagag gaagacgatc gcccactctt    780

ccagcccttg cttggtcaca ggttacacag atgccaagag aacccgggtg gccagcagca    840

gccaacgctc ccgtggctcc aaggtcggca gacagccagg gaagacgcgc aacaggtcag    900

ggatggcatg caagaccacc gccaccacca gctctaagcg aatcgtccgt cgtccatcct    960

taccgagttt gagtttgaag aaacccatta tcctccgaag ctctgggtgt caagtcccca   1020

ccgtcctccg ccgaggctat ctccaactgt tcaccgaaga gtgtctcaag ttctgcgcct   1080

ccaagcagga ggccgaggag aaggcgctga acgaggagaa ggtggcctac gactgcagcc   1140

ccaacaagaa caggtacctg aacgtggtcc tgaacaccct caagagactg aagggcctga   1200

cccccagctc catgcccggc ctcagcaggg ccgccctgta cagccgcctc caggagttcc   1260

tgctcaccca ggaccagctc aaggagaacg gctacccctt cccgcacccc gagcggcccg   1320

gaggcgccgt cctcttcact ggccagggga aggggcccgg cgactcctcc tgcagggtct   1380

gctgccgttg tggcaccgag tacctggtgt cctcctcggg ccgctgtgta cgcgaccagt   1440

tgtgttatta tcactggggg cgggtccgct cgagccaggt ggctggaggc cgggttagcc   1500

agtacacctg ctgtgcagct gctcctggct ctgtgggctg ccaggtggca aagcagcacg   1560

tgcgggacgg ccgcaaggag agcctccatg gcttcgtgga gaccttcaag aaagagttgt   1620

ccagagacgc ttatccagga atctacgcct tggactgtga gatgtgctac accacgcatg   1680

gcctagagct ggcccgcgtc accgtggtgg acgccgacat gcgagtggtg tacgacacct   1740

tcgtcaagcc cgacaacgag atcgtggact acaacaccag gttttccgga gtcaccgagg   1800

ccgacgtcgc taagacgagc atcacgttgc cccaagtcca agccatcctg ctgagctttt   1860

tcagcgccca aaccatcctc atcgggcaca gcctggagag cgacctgctg gccctgaagc   1920

tcatccacag caccgtggtg gacacggccg tgctcttccc gcactacctg ggtttcccct   1980

acaagcgctc cctcaggaat ctcgcggccg actacctggc acagatcatc caggacagcc   2040

aggacggcca caactccagc gaggacgcaa acgcctgcct gcagctggtg atgtggaagg   2100

tccgacagcg cgcccagatc cagccacgcc accggtccgc ctctcccgcc gccctggcct   2160

gtccttagcc ccaggcctct tccaaaaccg ccatcagtcc cgagagctca ccctgcccac   2220

ctcgccgcaa agcgaaagaa actggagcag ccggcggcag gagagggcaa aaagccaaga   2280

gtaaccccaa ccccccactc ccggtccccc ggaatccctg ccgcggcccc tcgggcctgt   2340

ccacatccct ctgcccctcc cagacctctg tccttccacc aatcgcctcc cgcagccccg   2400

agccgccact cccagtcccc cgagtccctg ccgcgcgccc tcgcgcctgt ccacatccct   2460

ctgcccatcc gagacctctg tccttacacc actagccacc ccacgtggga cttccatggc   2520

ttctgagtac aaggccagcc ccccggccca ccagctttcg gaatgcctgc ttacctcttt   2580

ttctgtctat ttacggttgt tgcttcctaa acataaacta cgtttaggct gatatttcag   2640

acaatgaaac ctttgagtgc ccgtagcggg aagatctcgg ttgctgagtg cagggaagga   2700

ggatgtaatt ccatcatata tactctctgt gcctaccgca tttggaacca tgcgagtgat   2760

acgtatttat aaaataaaat aaaccaagca caagtacgaa cttagcaaca ctatattgag   2820

ttaatagaac ggtatcttgt atttcttctg tccaggtata cttataaatg cctgcaggga   2880

tttcaccacc tcagggtgga gagactgaat gcttgtgagg gaattaggat ggtggaatat   2940

tggtgttacc agggaagggg gcgggatgtt tgaaaatgct atgtttactc gttcttgggt   3000

tccaataaag gagaaacagg gcacaggagt cggaaggact agtggcaata gtgatgaaag   3060

gacctcctta tcatgctggc catgttaatt acccaggtgt aggaagccat acactgaggc   3120

ggaagatcgc aagtcagagt ggccggcagg cacaacgtcc tggcacacca gaggcaggtc   3180

ttcaataccc actggtttcc ccaacaggct gcgtaaggga ccctgagcca cagtgagttg   3240

gtcaaatgct cctgacagtg tggagaaacc aacaggcaaa acgtgggtgc aaaagtgatg   3300

agaccccaca ctttacactc gtggtgacaa tgaagctatt atgtaacagc ttctcaacct   3360

atgctgtttc ctgttggatg cacataatcc atttgcactg cagacaattt taggatgtgg   3420

tttacagtaa ggtggatggt accttatggc aaaaatctct cagaaattta tgtgtggttt   3480

taaagtcatt ccagtcctag cacgttgtgc ttttcagaga cgccatagct gtttttccct   3540

ttgtaatatc aaagcagtaa tatgttctct ggaggcctgt tgggtgaatt taatggaatc   3600

aagttaagta ggtgccagaa ccattgctgt tttccctcca tagccctgcc acccactgta   3660

aaaaggttga tgagattact taatgatttc caattaagtt gtatttccaa atatcatgat   3720

ttccatttta atgtagttgg tatggagctc tgtgagtgtg tgcttctttt attatggatc   3780

acgttcagct tctttttatt tgcctcctag tcataatagt aaaactctac tcctctactc   3840

cgaggagtcc ctaccaccca tctcatcact ttccagccca gcactcttca tgctcattca   3900

tttaaagcat tcaacattgt gtaaatgaat cttggaaggc aaaagctact gaatttagcg   3960

aatttgtgga ggcattgcca caaatcagcc aggtgaagtt tcacacaatc gaagactgca   4020

caactcctag aaggcagcac tatgctgcaa acccagacgg ccactcttct cacccctcgt   4080

ccgtttgctg ttctggataa tgaggttcaa aagtcaccta ggcaactgcc aaaatagctg   4140

aaatggagaa agggcttcag gctggtgact agcaaaggtc cacctgaccc ccgtaagctg   4200

ctgaacaagt agggctgcca gaaatgtccc actagggaat ttggtagaga cgaagacatg   4260

ctcaccggac aagggttcct cccaggatac gcccgagcgg aagaagcggg ctctgagcca   4320

cgccctttca ccctcctcta ccccgccctg ggctggtgaa ggtgcgcgcc aggatgtgga   4380

ctactgagcc ctgaagaaat aagtccttcc actttgaccc catggaggat tgcctgtgag   4440

gaacttaaac gagtctacca gtgtctagac acgggggcag gtctgtccgg cacagcagct   4500

ccctcaagga ggagaagagt gaggagaaag gaaactcaag tctcaccatt ctgtcctggg   4560

agagaagagg aggatctcat ctctcatctg tccaaacaag gcaaggagac tttctctcat   4620

ctttccaagc aaggcaagga cctgtgttga acattgccca agtcctggga gagaagtggg   4680

tgcggtccgc ttcctgtcct caatttgccc gcagcggcgg agtgcacaga gcagggaaag   4740

gcagccccag agggatcccg ccctccagca tgcactaggt agcccaattc cagtagccat   4800

tataggactg ccctgcaggg acagttactt aactcaggaa aagcaaccta gctccaagtt   4860

tagcaaccgg gagttccagt tgattccatt agcgcacccc ctgaggcatt cccaagctgg   4920

agtctggtgg aagatgaggc tcagtgtgat tggactgaag caccaaccta tcaaggagaa   4980

gtcccaccca gtctgccctg tgcctatata aaggcgacaa gtggcggccg cagcactcat   5040

tgaagccgcc agttgggaga ggagcagagc caggccggtg ctcccgaagg cagcaagatg   5100

ttgcgagcca cagctccctg ctggttcccc cctggatacc cagaagctaa gaaggtggcc   5160

gaggaggcgg ccctggaggc aagccgccat ctgggagggg agcagagcca ggccggtgct   5220

cccgaaggca gcaagatgtt gcgagccaca gctccctgct ggttcccccc tggataccca   5280

gaagctaaga aggtggccaa ggaggcggcc ccggaggcaa gccgccattt gggagcggag   5340

cagagcccgg ccggtgctcc cgaaggcagc aagatgttgc gagccacagc tccctgctgg   5400

tt                                                                  5402


<210>  5926
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  5926

Met Ala Ser Glu Tyr Lys Ala Ser Pro Pro Ala His Gln Leu Ser Glu 
1               5                   10                  15


Cys Leu Leu Thr Ser Phe Ser Val Tyr Leu Arg Leu Leu Leu Pro Lys 
            20                  25                  30


His Lys Leu Arg Leu Gly 
        35


<210>  5927
<211>  1607
<212>  DNA
<213>  Homo sapiens

<400>  5927
ggcggagccc cagaacaggg gtccggcggt gcccccagcg tggcccaaga tggtgacgga     60

gtcgtgctac ttccctgcgc agaggggatc ggcctgccgc ttgccagccg ccccaaggct    120

gacagagagg ccctcgggag tccgcatctc agcccccagg aagaggaaga cgatcgccca    180

ctcttccagc ccttgcttgg tcacaggtta cacagatgcc aagagaaccc gggtggccag    240

cagcagccaa cgctcccgtg gctccaaggt cggcagacag ccagggaaga cgcgcaacag    300

gtcagggatg gcatgcaaga ccaccgccac caccagctct aagcgaatcg tccgtcgtgc    360

atccttaccg agtttgagtt tgaagaaacc cattatcctc cgaagctctg ggtgccaagt    420

ccccaccgtc ctccgccgag gctatctcca actgttcacc gaagagtgtc tcaagttctg    480

cgcctccaag caggaggccg aggagaaggc gctgaacgag gagaaggtgg cctacgactg    540

cagccccaac aagaacaggt acctgaacgt ggtcctgaac accctcaaga gactgaaggg    600

cctgaccccc agctccatgc ccggcctcag cagggccgcc ctgtacagcc gcctccagga    660

gttcctgctc acccaggacc agctcaagga gaacggctac cccttcccgc accccgagcg    720

gcccggaggc gccgtcctct tcactggcca ggggaagggg cccggcgact cctcctgcag    780

ggtctgctgc cgttgtggca ccgagtacct ggtgtcctcc tcgggccgct gtgtacgcga    840

ccagttgtgt tattatcact gggggcgggt ccgctcgagc caggtggctg gaggccgggt    900

tagccagtac acctgctgtg cagctgctcc tggctctgtg ggctgccagg tggcaaagca    960

gcacgtgcgg gacggccgca aggagagcct cgatggcttc gtggagacct tcaagaaaga   1020

gttgtccaga gacgcttatc caggaatcta cgccttggac tgtgagatgt gctacaccac   1080

gcatggccta gagctgaccc gcgtcaccgt ggtggacgcc gacatgcgag tggtgtacga   1140

caccttcgtc aagcccgaca acgagatcgt ggactacaac accaggtttt ccggagtcac   1200

cgaggccgac gtcgccaaga cgagcatcac gttgccccaa gtccaagcca tcctgctgag   1260

ctttttcagc gcccaaacca tcctcatcgg gcacagcctg gagagcgacc tgctggccct   1320

gaagctcatc cacagcaccg tggtggacac ggccgtgctc ttcccgcact acctgggttt   1380

cccctacaag cgctccctca ggaatctcgc ggccgactac ctggcacaga tcatccagga   1440

cagccaggac ggccacaact ccagcgagga cgcaaacgcc tgcctgcagc tggtgatgtg   1500

gaaggtccga cagcgcgccc agatccagcc acgccaccgg tccgcctctc ccgccgccct   1560

ggcctgtcct tagccccagg cctcttccaa aaccgccatc agtcccg                 1607


<210>  5928
<211>  507
<212>  PRT
<213>  Homo sapiens

<400>  5928

Met Val Thr Glu Ser Cys Tyr Phe Pro Ala Gln Arg Gly Ser Ala Cys 
1               5                   10                  15


Arg Leu Pro Ala Ala Pro Arg Leu Thr Glu Arg Pro Ser Gly Val Arg 
            20                  25                  30


Ile Ser Ala Pro Arg Lys Arg Lys Thr Ile Ala His Ser Ser Ser Pro 
        35                  40                  45


Cys Leu Val Thr Gly Tyr Thr Asp Ala Lys Arg Thr Arg Val Ala Ser 
    50                  55                  60


Ser Ser Gln Arg Ser Arg Gly Ser Lys Val Gly Arg Gln Pro Gly Lys 
65                  70                  75                  80


Thr Arg Asn Arg Ser Gly Met Ala Cys Lys Thr Thr Ala Thr Thr Ser 
                85                  90                  95


Ser Lys Arg Ile Val Arg Arg Ala Ser Leu Pro Ser Leu Ser Leu Lys 
            100                 105                 110


Lys Pro Ile Ile Leu Arg Ser Ser Gly Cys Gln Val Pro Thr Val Leu 
        115                 120                 125


Arg Arg Gly Tyr Leu Gln Leu Phe Thr Glu Glu Cys Leu Lys Phe Cys 
    130                 135                 140


Ala Ser Lys Gln Glu Ala Glu Glu Lys Ala Leu Asn Glu Glu Lys Val 
145                 150                 155                 160


Ala Tyr Asp Cys Ser Pro Asn Lys Asn Arg Tyr Leu Asn Val Val Leu 
                165                 170                 175


Asn Thr Leu Lys Arg Leu Lys Gly Leu Thr Pro Ser Ser Met Pro Gly 
            180                 185                 190


Leu Ser Arg Ala Ala Leu Tyr Ser Arg Leu Gln Glu Phe Leu Leu Thr 
        195                 200                 205


Gln Asp Gln Leu Lys Glu Asn Gly Tyr Pro Phe Pro His Pro Glu Arg 
    210                 215                 220


Pro Gly Gly Ala Val Leu Phe Thr Gly Gln Gly Lys Gly Pro Gly Asp 
225                 230                 235                 240


Ser Ser Cys Arg Val Cys Cys Arg Cys Gly Thr Glu Tyr Leu Val Ser 
                245                 250                 255


Ser Ser Gly Arg Cys Val Arg Asp Gln Leu Cys Tyr Tyr His Trp Gly 
            260                 265                 270


Arg Val Arg Ser Ser Gln Val Ala Gly Gly Arg Val Ser Gln Tyr Thr 
        275                 280                 285


Cys Cys Ala Ala Ala Pro Gly Ser Val Gly Cys Gln Val Ala Lys Gln 
    290                 295                 300


His Val Arg Asp Gly Arg Lys Glu Ser Leu Asp Gly Phe Val Glu Thr 
305                 310                 315                 320


Phe Lys Lys Glu Leu Ser Arg Asp Ala Tyr Pro Gly Ile Tyr Ala Leu 
                325                 330                 335


Asp Cys Glu Met Cys Tyr Thr Thr His Gly Leu Glu Leu Thr Arg Val 
            340                 345                 350


Thr Val Val Asp Ala Asp Met Arg Val Val Tyr Asp Thr Phe Val Lys 
        355                 360                 365


Pro Asp Asn Glu Ile Val Asp Tyr Asn Thr Arg Phe Ser Gly Val Thr 
    370                 375                 380


Glu Ala Asp Val Ala Lys Thr Ser Ile Thr Leu Pro Gln Val Gln Ala 
385                 390                 395                 400


Ile Leu Leu Ser Phe Phe Ser Ala Gln Thr Ile Leu Ile Gly His Ser 
                405                 410                 415


Leu Glu Ser Asp Leu Leu Ala Leu Lys Leu Ile His Ser Thr Val Val 
            420                 425                 430


Asp Thr Ala Val Leu Phe Pro His Tyr Leu Gly Phe Pro Tyr Lys Arg 
        435                 440                 445


Ser Leu Arg Asn Leu Ala Ala Asp Tyr Leu Ala Gln Ile Ile Gln Asp 
    450                 455                 460


Ser Gln Asp Gly His Asn Ser Ser Glu Asp Ala Asn Ala Cys Leu Gln 
465                 470                 475                 480


Leu Val Met Trp Lys Val Arg Gln Arg Ala Gln Ile Gln Pro Arg His 
                485                 490                 495


Arg Ser Ala Ser Pro Ala Ala Leu Ala Cys Pro 
            500                 505


<210>  5929
<211>  5086
<212>  DNA
<213>  Homo sapiens

<400>  5929
atgttgcgag ccacagctcc ctgctggttc ccacctggat acccagaagc taagaaggtg     60

gccgaggagg cggccctcga ggctccagaa ttcccactgc cctctcatca gcctgcccag    120

agcttcgggc tctgggtgcc ccagatgcac aagcaggcct cagcatttgt ggacatccag    180

gcggagcccc agaacagggg tccggcggtg cccccagcgt ggcccaagat ggtgacggag    240

tcgtgctact tccctgcgca gaggggatcg gcctgccgct tgccagccgc cccaaggctg    300

acagagaggc cctcgggagt ccgcatctca gcccccagga agaggaagac gatcgcccac    360

tcttccagcc cttgcttggt cacaggttac acagatgcca agagaacccg ggtggccagc    420

agcagccaac gctccattgg ctcccaggtc ggcagacagc cagggaagac gcgcaagagg    480

tcagggatgg catgcaagac caccgccacc atcagctcta agcgaatcgt ccgtcgtcta    540

tccttaccga gtttgaagaa acccattatc ctccgaagct ctgggtgcca agtccccacc    600

atcctccgcc gatgctatct ccaactgttc accgaagagt gtctcaagtt ctgcgcctcc    660

aagcaggagg ccgaggagaa ggcgctgaac gaggagaagg tggcctacga ctgcagcccc    720

aacaagaaca ggtacctgaa cgtggtcctg aacaccctca agagactgaa gggcctgacc    780

cccagctcca tgcccggcct cagcagggcc gccctgtaca gccgcctcca ggagttcctg    840

ctcacccagg accagctcaa ggagaacggc taccccttcc cgcaccccga gcggcccgga    900

ggcgccgtcc tcttcactgg ccaggggaag gggcccggcg actcctcctg cagggtctgc    960

tgccgttgtg gcaccgagta cctggtgtcc tccttgggcc gctgtgtacg cgaccagttg   1020

tgttattatc actgggggcg ggtccgctcg agccaggtgg ctggaggccg ggttagccag   1080

tacacctgct gtgcagctgc tcctggctct gtgggctgcc aggtggcaaa gcagcacgtg   1140

cgggacggcc gcaaggagag cctccatggc ttcgtggaga ccttcaagaa agagttgtcc   1200

agagacgctt atccaggaat ctacgccttg gactgtgaga tgtgctacac cacgcatggc   1260

ctagagctga cccgcgtcac cgtggtggac gccgacatgc gagtggtgta cgacaccttc   1320

gtcaagcccg acaacgagat cgtggactac aacaccaggt tttccggagt caccgaggcc   1380

gacgtcgcca agacgagcat cacgttgccc caagtccaag ccatcctgct gagctttttc   1440

agcgcccaaa ccatcctcat cgggcacagc ctggagagcg acctgctggc cctgaagctc   1500

atccacagca ccgtggtgga cacggccgtg ctcttcccgc actacctggg tttcccctac   1560

aagcgctccc tcaggaatct cgcggccgac tacctggcac agatcatcca ggacagccag   1620

gacggccaca actccagcga ggacgcaaac gcctgcctgc agcttggtga tgtggaaggt   1680

caacagcgcg cccagatcca gccacgccac cggtccgcct ctcccgccgc cctggcctgt   1740

ccttagcccc aggcctcttc caaaaccgcc atcagtcccg agagctcacc ctgcccacct   1800

cgccgcaaag cgaaagaaac tggagcagcc ggcggcagga gagggcaaaa agccaagagt   1860

aaccccaacc cccgactccc ggtaccccgg aatccctgcc gcggcccctc gggcctgtcc   1920

acatccctct gcccctccca gacctctgac cgtccaccaa gcgcctcccg cagccccgag   1980

ccgccactcc caggcccccg agtccctgcc gcgcgccctc gcgccggacc acatccctct   2040

gcccatccga gacctctgtc cttacaccac tagccacccc acgtgggact tccatggctt   2100

ctgagtacaa ggccagcccc ccggcccacc agctttcgga atgcctgctt acctcttttt   2160

ctgtctattt acggttgttg cttcctaaac ataaactacg tttaggctga tatttcagac   2220

aatgaaacct ttgagtgccc gtagcgggaa gatctcggtt gctgagtgca gggaaggagg   2280

atgtaattcc atcatatata ctctctgtgc ctaccgcatt tggaaccatg cgagtgatac   2340

gtatttataa aataaaataa accaagcaca agtacgaact tagcaacact atattgagtt   2400

aatagaacgg tatcttgtat ttcttctgtc caggtatact tataaatgcc tgcagggatt   2460

tcaccacctc agggtggaga gactgaatgc ttgtgaggga attaggatgg tggaatattg   2520

gtgttaccag ggaagggggc gggatgtttg aaaatgctat gtttactcgt tcttgggttc   2580

caataaagga gaaacagggc acaggagtcg gaaggactag tggcaatagt gatgaaagga   2640

cctccttatc atgctggcaa tgttaattac ccaggtgtag gaagccatac actgaggcgg   2700

aagatcgcaa gtcagagtgg ccggcaggca caacgtcctg gcacaccaga ggcaggtctt   2760

caatacccac tggtttcccc aacaggctgc gtaagggacc ctgagccaca gtgagttggt   2820

gaaatgctcc tgacagtgtg gagaaaccaa caggcaaaac gtgggtgcaa aagtgatgag   2880

accccacact ttacactcgt ggtgacaatg aagctattaa gtaacagctt ctcaacctat   2940

gctgtttcct gttggatgca cataatccat ttgcactgca gacaatttta ggatgtggtt   3000

tacagtaagg tggatggtac cttatggcaa aaatctctca gaaatttatg tgtggtttta   3060

aagtcattcc agtcctagca cgttgtgctt ttcagagacg ccatagctgt ttttcccttt   3120

gtaatatcaa agcagtaata tgttctctgg aggcctgttg ggtgaattta atggaatcaa   3180

gttaagtagg tgccagaacc attgctgttt tccctccata gccctgccac ccactgtaaa   3240

aaggttgatg agattactta atgatttcca attaagttgt atttccaaat atcatgattt   3300

ccattttaat gtagttggta tggagctctg tgagtgtgtg cttcttttat tatggatcac   3360

gttcagcttc tttttatttg cctcctagtc ataatagtaa aactctactc ctctactccg   3420

aggagtccct accacccatc tcatcacttt ccagcccagc actcttcatg ctcattcatt   3480

taaagcattc aacattgtgt aaatgaatct tggaaggcaa aagctactga atttagcgaa   3540

tttgtggagg cattgccaca aatcagccag gtgaagtttc acacaatcga agactgcaca   3600

actcctagaa ggcagcacta tgctgcaaac ccagacggcc actcttctca cccctcgtcc   3660

gtttgctgtt ctggataatg aggttcaaaa gtcacctagg caactgccaa aatagctgaa   3720

atggagaaag ggcttcaggc tggtgactag cagaggtcca cctgaccccc gtaagctgct   3780

gaacaagtag ggctgccaga aatgtcccac tagggaattt ggtagagacg aagacatgct   3840

caccggacaa gagttcctcc caggatacgc ccgagcggaa gaagcgggct ctgagccacg   3900

ccctttcacc ctcctctacc ccgccctggg ctggtgaagg tgcgcgccag gatgtggact   3960

actgagccct gaagaaataa gtccttccac tttgacccca tggaggattg cctgtgagga   4020

acttaaacga gtctaccagt gtctagacac gggggcaggt ctgtccggca cagcagctcc   4080

ctcaaggagg agaagagtga ggagaaagga aactcaagtc tcaccattct gtcctgggag   4140

agaagaggag gatctcatct ctcatctgtc caaacaaggc aaggagactt tctctcatct   4200

ttccaagcaa ggcaaggacc tgtgttgaac attgcccaag tcctgggaga gaagtgggtg   4260

cggtccgctt cctgtcctca atttgcccgc agcggcggag tgcacagagc agggaaaggc   4320

agccccagag ggatcccgcc ctccagcatg cagcagactg ctggcccagt cctggctcca   4380

aggggtgctg tgtgggccca agcaagttga ccaacctccc tgaaccttaa tttcatccta   4440

ggtagcccaa ttccagtagc cattatagga ctgccctgca gggacagtta cttaactcag   4500

gaaaagcaac ctagctccaa gtttagcaac cgggagttcc agttgattcc attagcgcac   4560

cccctgaggc attcccaagc tggagtctgg tggaagatga ggctcagtgt gattggactg   4620

aagcaccaac ctatcaagga gaagtcccac ccagtctgcc ctgtgcctat ataaaggcga   4680

caagtggcgg ccgcagcact cattgaagcc gccagttggg agaggagcag agccaggccg   4740

gtgctcccga aggcagcaag atgttgcgag ccacagctcc ctgctggttc ccccctggat   4800

acccagaagc taagaaggtg gccgaggagg cggccctgga ggcaagccgc catttgggag   4860

gggagcagag ccaggccggt gctcccgaag gcagcaagat gttgcgagcc acagctccct   4920

gctggttccg ccctggatac ccagaagcta agaaggtggc caaggaggcg gccccggagg   4980

caagccgcca tttgggagcg gagcagagcc cggccggtgc tcccgaaggc agcaagatgt   5040

tgcgagccac agctccctgc tggttcccac ctggataccc agaagc                  5086


<210>  5930
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  5930

Met Ala Ser Glu Tyr Lys Ala Ser Pro Pro Ala His Gln Leu Ser Glu 
1               5                   10                  15


Cys Leu Leu Thr Ser Phe Ser Val Tyr Leu Arg Leu Leu Leu Pro Lys 
            20                  25                  30


His Lys Leu Arg Leu Gly 
        35


<210>  5931
<211>  517
<212>  DNA
<213>  Homo sapiens

<400>  5931
gccttctcct gtctgccacc acgtgagatg tgcctttcac cttccactat gattgtgagg     60

cctcaccagc catgtggaac tagttcaaga tttcaacatt ttaagataat ctgaaaaaaa    120

ttggaatgtg cccccagctg cgctactggt gacttcttca acagttgaga aactgaacta    180

tgtgttcatg aaaatactcc atcattaaag tttatgcaat actctctcaa cactgtttat    240

caaaggaacc aatatggaag gaaaaacatt gctttgaagg gaagatggat ggatccccta    300

gtaaactaca gcttgaggtg caatttccta aagttcaaat gcctgaaaaa ggaaacgaaa    360

gaaagaaact caactcttga gacagcttca atgctagctt tgatctcaat tatagagtta    420

tttatgaaaa gtgcattttt acaactaaaa ataaattagg atcaaaagct tctagaggct    480

atactatgga gtgcttaata aaaagttgag taaagag                             517


<210>  5932
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  5932

Met Gln Tyr Ser Leu Asn Thr Val Tyr Gln Arg Asn Gln Tyr Gly Arg 
1               5                   10                  15


Lys Asn Ile Ala Leu Lys Gly Arg Trp Met Asp Pro Leu Val Asn Tyr 
            20                  25                  30


Ser Leu Arg Cys Asn Phe Leu Lys Phe Lys Cys Leu Lys Lys Glu Thr 
        35                  40                  45


Lys Glu Arg Asn Ser Thr Leu Glu Thr Ala Ser Met Leu Ala Leu Ile 
    50                  55                  60


Ser Ile Ile Glu Leu Phe Met Lys Ser Ala Phe Leu Gln Leu Lys Ile 
65                  70                  75                  80


Asn 



<210>  5933
<211>  359
<212>  DNA
<213>  Homo sapiens

<400>  5933
gagtcattaa atctcaagga tatctatttg gtcatgtttt cttgtggtat ttcaaggcta     60

ctggtgactt cttcaacagt tgagaaactg aactatgtgt tcatgaaaat actccatcat    120

taaagtttat gatcttgtcc atcattctta acaatttgac agcgtgtcca gaacattgcg    180

cctaaatgaa tctaacaaga ggtaagttga acataatatt ggtatttgaa agtcttcaat    240

agaattaggc ccttaattta gctttttcta agactttaaa cattcaaatg tttcttctgc    300

ttatacttaa atagtcttta aggcaactta tttgttccct gaacaaactt cagttgctt     359


<210>  5934
<211>  854
<212>  DNA
<213>  Homo sapiens

<400>  5934
aacctgggat gagatcctcg tttcagaaaa tgatttgatc ctcctgaagg cgctccctgc     60

taaggatcta aactcaggag acgggatttc accatgtttg ccaggctggt cttgaactcc    120

tgacctgaag tgatctgccc acctcagcct cccaaagtgt tgggattaca gagcatctct    180

cagggattct taaaataaaa taagtcactg tgaatacaca aaggaaatga aaacatatac    240

agagtgtgaa ataacagcca aaaaggctag tgcaaatctt caggggccgt ccaggactac    300

agagctgttt caccctacct tggcttcaat ctcttccccc atgctcgaag gtgcggagct    360

gtacttcaac gtggaccatg gctacctgga gggcctggtt cgaggatgca aggccagcct    420

cctgacccag caagactata tcaacctggt ccagtgtgag accctagaag gtaagtgtag    480

ctcttctcac cctttaaaaa gaaaaaaaaa aaaatgaaat gatgtccctc tccagaagca    540

tggagaaaaa aagcccataa tcatatggtt tgagagttct gagcagatcc ttattcctgc    600

agtccagatt tctggggtcc ataaacttga atgaggaaaa aaaaataaat ctctattttt    660

aatctctaag tgaactataa catctttcat tactaatgta ggcaacaaat cacagtagtt    720

gagataagta gtatctgtga cactgtcacc aacaaaaatt caatgttttc atatcccttt    780

aaagttcttg cagatacctt gaaatgtcat gtatgttttc tctattttga agtaagatac    840

cacactcatc cttt                                                      854


<210>  5935
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  5935

Met Lys Thr Tyr Thr Glu Cys Glu Ile Thr Ala Lys Lys Ala Ser Ala 
1               5                   10                  15


Asn Leu Gln Gly Pro Ser Arg Thr Thr Glu Leu Phe His Pro Thr Leu 
            20                  25                  30


Ala Ser Ile Ser Ser Pro Met Leu Glu Gly Ala Glu Leu Tyr Phe Asn 
        35                  40                  45


Val Asp His Gly Tyr Leu Glu Gly Leu Val Arg Gly Cys Lys Ala Ser 
    50                  55                  60


Leu Leu Thr Gln Gln Asp Tyr Ile Asn Leu Val Gln Cys Glu Thr Leu 
65                  70                  75                  80


Glu Gly Lys Cys Ser Ser Ser His Pro Leu Lys Arg Lys Lys Lys Lys 
                85                  90                  95


<210>  5936
<211>  629
<212>  DNA
<213>  Homo sapiens

<400>  5936
gaattgcaaa gtcagcaaag ataggaggtt ataagatttg ggtgagtgga attaacttgg     60

ggagaatgag gtcatcacct tctcactcca ctctaccgct aaagcaatga gatccggtct    120

aatgtctcct gaaccctaag atgtaacttg ctttggtgat ctcacagatg tgataagaaa    180

actgagaaga cagagaggtt aaatatcttt cctaaggtca cagaactgat atgacatcaa    240

agctcttatt gggacaggca gtttcagcag ggttgtcagg gtagagcaga agaccaccaa    300

gaaacctttt gcaataaaag tgatggaaac cagagagagg gaaggtagag aagcgtgcgt    360

gtctgagctg agcgtcctgc ggcgggttag ccatcgttac attgtccagc tcatggagat    420

ctttgagact gaggatcaag tttacatggt aatggagctg gctaccggag gggagctctt    480

tgatcgactc attgctcagg gatcctttac agagcgggat gccgtcagga tcctccagat    540

ggttgctgat gggattaggt atttgcatgc gctgcagata actcatagga atctaaagcc    600

tgaaaacctc ttatactatc atccaggtg                                      629


<210>  5937
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  5937

Met Glu Thr Arg Glu Arg Glu Gly Arg Glu Ala Cys Val Ser Glu Leu 
1               5                   10                  15


Ser Val Leu Arg Arg Val Ser His Arg Tyr Ile Val Gln Leu Met Glu 
            20                  25                  30


Ile Phe Glu Thr Glu Asp Gln Val Tyr Met Val Met Glu Leu Ala Thr 
        35                  40                  45


Gly Gly Glu Leu Phe Asp Arg Leu Ile Ala Gln Gly Ser Phe Thr Glu 
    50                  55                  60


Arg Asp Ala Val Arg Ile Leu Gln Met Val Ala Asp Gly Ile Arg Tyr 
65                  70                  75                  80


Leu His Ala Leu Gln Ile Thr His Arg Asn Leu Lys Pro Glu Asn Leu 
                85                  90                  95


Leu Tyr Tyr His Pro 
            100


<210>  5938
<211>  878
<212>  DNA
<213>  Homo sapiens

<400>  5938
gataaaataa gttcctatgg tgaggaatgg aggcctccag ctgacagaga gcaaagaact     60

gaggcctgcg acaactatag gcgtgatcct gggaaccgat tctcaacctc atctgagcct    120

tgagacgact gctgctctgg ccgacagcct gacggcaacc tcctgagaca gctctgagag    180

gagattttcc aggttcaagt cccgagacga ggtttcaccg tgctggccaa gctggtctcc    240

acctcaggtg atctgccccg ctaagcctcc gcaagtgctg ggattacagg ctagtgcaaa    300

tcttcagggg ccgtccagga ctacagagct gtttcaccct accttggctt caatctcttc    360

ccccatgctc gaaggtgcgg agctgtactt caacgtggac catggctacc tggagggcct    420

ggttcgagga tgcaaggcca gcctcctgac ccagcaagac tatatcaacc tggtccagtg    480

tgagacccta gaaggtaagt gtagctcttc tcacccttta aaaagaaaaa aaaaaaaatg    540

aaatgatgtc cctctccaga agcatggaga aaaaaagccc ataatcatat ggtttgagag    600

ttctgagcag atccttattc ctgcagtcca gatttctggg gtccataaac ttgaatgagg    660

aaaaaaaaat aaatctctat ttttaatctc taagtgaact ataacatctt tcattactaa    720

tgtaggcaac aaatcacagt agttgagata agtagtatct gtgacactgt caccaacaaa    780

aattcaatgt tttcatatcc ctttaaagtt cttgcagata ccttgaaatg tcatgtatgt    840

tttctctatt ttgaagtaag ataccacact catccttt                            878


<210>  5939
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  5939

Met Leu Glu Gly Ala Glu Leu Tyr Phe Asn Val Asp His Gly Tyr Leu 
1               5                   10                  15


Glu Gly Leu Val Arg Gly Cys Lys Ala Ser Leu Leu Thr Gln Gln Asp 
            20                  25                  30


Tyr Ile Asn Leu Val Gln Cys Glu Thr Leu Glu Gly Lys Cys Ser Ser 
        35                  40                  45


Ser His Pro Leu Lys Arg Lys Lys Lys Lys 
    50                  55


<210>  5940
<211>  2446
<212>  DNA
<213>  Homo sapiens

<400>  5940
acaaaaaccc tgactatcac ctgatagatt gcttgtgctg cctgataatt actcgcactt     60

ttcccaggct agtgcaaatc ttcaggggcc gtccaggact acagagctgt ttcaccctac    120

cttggcttca atctcttccc ccatgctcga aggtgcggag ctgtacttca acgtggacca    180

tggctacctg gagggcctgg ttcgaggatg caaggccagc ctcctgaccc agcaagacta    240

tatcaacctg gtccagtgtg agaccctaga agacctgaaa attcatctcc agactactga    300

ttatggtaac tttttggcta atcacacaaa tcctcttact gtttccaaaa ttgacactga    360

gatgaggaaa agactatgtg gagaatttga gtatttccgg aatcattccc tggagcccct    420

cagcacattt ctcacctata tgacgtgcag ttatatgata gacaatgtga ttctgctgat    480

gaatggtgca ttgcagaaaa aatctgtgaa agaaattctg gggaagtgcc accccttggg    540

ccgtttcaca gaaatggaag ctgtcaacat tgcagagaca ccttcagatc tctttaatgc    600

cattctgatc gaaacgccat tagctccatt cttccaagac tgcatgtctg aaaatgctct    660

agatgaactg aatattgaat tgctacgcaa taaactatac aagtcttacc ttgaggcatt    720

ctataaattc tgtaagaatc atggtgatgt cacagcagaa gttatgtgtc ccattcttga    780

gtttgaggcc gacagacgtg cttttatcat cactcttaac tcctttggca ctgaattgag    840

caaagaagac cgagagaccc tctatccaac cttcggcaaa ctctatcctg aggggttgcg    900

gctgttggct caagcagaag actttgacca gatgaagaac gtagcggatc attacggagt    960

atacaaacct ttatttgaag ctgtaggtgg cagtggggga aagacattgg aggacgtgtt   1020

ttacgagcgt gaggtacaaa tgaatgtgct ggcattcaac agacagttcc actacggtgt   1080

gttttatgca tatgtaaagc tgaaggaaca ggaaattaga aatattgtgt ggatagcaga   1140

atgtatttca cagaggcatc gaactaaaat caacagttac attccaattt tataacccaa   1200

gtaaggttct caaatgtaga aaattataaa tgttaaaagg aagttattga agaaaataaa   1260

agaaattatg ttatattatc tagactacac aaaagtaagc cacactatat cttcatgagt   1320

tgcaaatcca tggaaacaca gtaaaccagc cctgaaacaa agcatttcct tgttttcagt   1380

ggtattagat cttgtttcca catgtctgtc tcattcttca ctgggcctta caggttagtt   1440

ttaattaact ctatggtatt tttcttattc ttgtttgatc atgttaaaaa ttggacctaa   1500

taaaagtatt ttattcttgc ttttccatgc ttctctacag gtccaaatac tgaatgtctc   1560

ctttactttt tctcttttaa atttttttct agacagggtc tcactctgtc acctaggcta   1620

cagtgcagtg gtgtgatcac agctcactgc agcctcgact tcccaggctc aagtgatcct   1680

cccagctctc agcctccaaa gtagctggca ctacaagtgt acacccccac acaaggctaa   1740

gttttgtatt ttttgtagag acagggtttc aacatattat ccaggctggt gtcgaattcc   1800

tgggctccag ggatccacag tcccccttgg cctcccaaag tgttgggatt acatgcatga   1860

gccactgtgc tgggcttcat ttacatttta actgtctgtt ccttgcctag attcacagaa   1920

atccaaagct gtatgtagtc aacatggttc acaagtgttg gaaaatgtgt tttttgtttt   1980

gttttgtttt gtttcgtttt gttttgagac agagtttccc tctgtcgccc aggctagagt   2040

gcaatggcgt gatctcggct cactgcaacc tccacctccc agattcaagc aactctctgc   2100

ctcagcctcc cgagtagctg ggattacaag cacccaccac tacactcagc taattttttg   2160

tatttttagt agagccgggg tttcaccatc ttggccaggc tgatcttgaa ctcctgagct   2220

catgatccac ccgcctcagc ctcccaaagt gctgggatta caggcccctt gttcagccac   2280

tgcacctggc cccttatttt gtttttgttt tctaatatac tttgatgtaa tcagcttgag   2340

aaagcaacac aatttcaaat cctatcttct agatgcaagc agtgttaaat ttgttaataa   2400

atttgctttt cacacctttc tttaaataaa aggtatatct ctcttt                  2446


<210>  5941
<211>  350
<212>  PRT
<213>  Homo sapiens

<400>  5941

Met Leu Glu Gly Ala Glu Leu Tyr Phe Asn Val Asp His Gly Tyr Leu 
1               5                   10                  15


Glu Gly Leu Val Arg Gly Cys Lys Ala Ser Leu Leu Thr Gln Gln Asp 
            20                  25                  30


Tyr Ile Asn Leu Val Gln Cys Glu Thr Leu Glu Asp Leu Lys Ile His 
        35                  40                  45


Leu Gln Thr Thr Asp Tyr Gly Asn Phe Leu Ala Asn His Thr Asn Pro 
    50                  55                  60


Leu Thr Val Ser Lys Ile Asp Thr Glu Met Arg Lys Arg Leu Cys Gly 
65                  70                  75                  80


Glu Phe Glu Tyr Phe Arg Asn His Ser Leu Glu Pro Leu Ser Thr Phe 
                85                  90                  95


Leu Thr Tyr Met Thr Cys Ser Tyr Met Ile Asp Asn Val Ile Leu Leu 
            100                 105                 110


Met Asn Gly Ala Leu Gln Lys Lys Ser Val Lys Glu Ile Leu Gly Lys 
        115                 120                 125


Cys His Pro Leu Gly Arg Phe Thr Glu Met Glu Ala Val Asn Ile Ala 
    130                 135                 140


Glu Thr Pro Ser Asp Leu Phe Asn Ala Ile Leu Ile Glu Thr Pro Leu 
145                 150                 155                 160


Ala Pro Phe Phe Gln Asp Cys Met Ser Glu Asn Ala Leu Asp Glu Leu 
                165                 170                 175


Asn Ile Glu Leu Leu Arg Asn Lys Leu Tyr Lys Ser Tyr Leu Glu Ala 
            180                 185                 190


Phe Tyr Lys Phe Cys Lys Asn His Gly Asp Val Thr Ala Glu Val Met 
        195                 200                 205


Cys Pro Ile Leu Glu Phe Glu Ala Asp Arg Arg Ala Phe Ile Ile Thr 
    210                 215                 220


Leu Asn Ser Phe Gly Thr Glu Leu Ser Lys Glu Asp Arg Glu Thr Leu 
225                 230                 235                 240


Tyr Pro Thr Phe Gly Lys Leu Tyr Pro Glu Gly Leu Arg Leu Leu Ala 
                245                 250                 255


Gln Ala Glu Asp Phe Asp Gln Met Lys Asn Val Ala Asp His Tyr Gly 
            260                 265                 270


Val Tyr Lys Pro Leu Phe Glu Ala Val Gly Gly Ser Gly Gly Lys Thr 
        275                 280                 285


Leu Glu Asp Val Phe Tyr Glu Arg Glu Val Gln Met Asn Val Leu Ala 
    290                 295                 300


Phe Asn Arg Gln Phe His Tyr Gly Val Phe Tyr Ala Tyr Val Lys Leu 
305                 310                 315                 320


Lys Glu Gln Glu Ile Arg Asn Ile Val Trp Ile Ala Glu Cys Ile Ser 
                325                 330                 335


Gln Arg His Arg Thr Lys Ile Asn Ser Tyr Ile Pro Ile Leu 
            340                 345                 350


<210>  5942
<211>  559
<212>  DNA
<213>  Homo sapiens

<400>  5942
agctgtttca ccctaccttg gcttcaatct cttcccccat gctcgaaggt gcggagatgg     60

ttcacaagtg ttggaaaatg tgttttttgt tttgttttgt tttgtttcgt tttgttttga    120

gacagagttt ccctctgtcg cccaggctag agtgcaatgg cgtgatctcg gctcactgca    180

acctccacct cccagattca agcaactctc tgcctcagcc tcccgagtag ctgggattac    240

aagcacccac cactacactc agctaatttt ttgtattttt agtagagccg gggtttcacc    300

atcttggcca ggctgatctt gaactcctga gctcatgatc cacccgcctc agcctcccaa    360

agtgctggga ttacaggccc cttgttcagc cactgcacct ggccccttat tttgtttttg    420

ttttctaata tactttgatg taatcagctt gagaaagcaa cacaatttca aatcctatct    480

tctagatgca agcagtgtta aatttgttaa taaatttgct tttcacacct ttctttaaat    540

aaaaggtata tctctcttt                                                 559


<210>  5943
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  5943

Met Leu Glu Gly Ala Glu Met Val His Lys Cys Trp Lys Met Cys Phe 
1               5                   10                  15


Leu Phe Cys Phe Val Leu Phe Arg Phe Val Leu Arg Gln Ser Phe Pro 
            20                  25                  30


Leu Ser Pro Arg Leu Glu Cys Asn Gly Val Ile Ser Ala His Cys Asn 
        35                  40                  45


Leu His Leu Pro Asp Ser Ser Asn Ser Leu Pro Gln Pro Pro Glu 
    50                  55                  60


<210>  5944
<211>  277
<212>  DNA
<213>  Homo sapiens

<400>  5944
caatctcttc ccccatgctc gaaggtgcgg agctgtactt caacgtggac catggctacc     60

tggagggcct ggttcgagga tgcaaggcca gcctcctgac ccagcaagac tatatcaacc    120

tggcccctta ttttgttttt gttttctaat atactttgat gtaatcagct tgagaaagca    180

acacaatttc aaatcctatc ttctagatgc aagcagtgtt aaatttgtta ataaatttgc    240

ttttcacacc tttctttaaa taaaaggtat atctctc                             277


<210>  5945
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  5945

Met Gln Gly Gln Pro Pro Asp Pro Ala Arg Leu Tyr Gln Pro Gly Pro 
1               5                   10                  15


Leu Phe Cys Phe Cys Phe Leu Ile Tyr Phe Asp Val Ile Ser Leu Arg 
            20                  25                  30


Lys Gln His Asn Phe Lys Ser Tyr Leu Leu Asp Ala Ser Ser Val Lys 
        35                  40                  45


Phe Val Asn Lys Phe Ala Phe His Thr Phe Leu 
    50                  55


<210>  5946
<211>  1877
<212>  DNA
<213>  Homo sapiens

<400>  5946
agaattattt tatttcagga atccatcaac atcctttgca gctacatagg caggaaaatc     60

tagaaattgt aatttatata gaattttaaa actcttcaat tacaatggat agaggggaga    120

aaatacagct caagagagtg tttggatatt ggtggggcac aagttttttg cttattaata    180

tcattggtgc aggaattttt gtgtccccca aaggtgtgtt ggcatactct tgcatgaacg    240

tgggagtctc cctgtgcgtt tgggctggct gtgccatact ggccatgaca tcaactcttt    300

gctctgcaga gataagtata agcttcccat gcagtggagc tcaatactat tttctcaaga    360

gatactttgg ctccacggtt gcttttttga atctctggac atccttgttt ctggggtcag    420

gggtagttgc tggccaagct ctgctccttg ctgagtacag catccagcct ttttttccca    480

gctgctctgt cccaaagctg cctaagaaat gtctggcatt ggccatgttg tggattgtag    540

gaattctgac ttctcgtggt gtgaaagaag tgacttggct tcagatagct agctcagtgc    600

tgaaagtgtc catacttagc ttcatttccc taactggagt agtgttcctg ataagaggga    660

aaaaggagaa tgtagaacga tttcagaatg cttttgatgc tgaacttcca gatatctctc    720

accttataca agccatcttc caaggatatt ttgcatattc aggcggggca tgctttacac    780

ttatagcagg ggagctgaag aagcccagaa caacaattcc caaatgcata tttactgcgt    840

tacctctggt gactgtagtt tatttactgg ttaacatttc ctatctgact gttctgacac    900

ccagggaaat tctctcttca gatgctgtag ctatcacatg ggctgatcga gcttttccct    960

cattagcatg gattatgcct tttgctattt ctacctcatt atttagcaac cttctgattt   1020

ctatatttaa atcatcgaga ccaatatatc ttgcaagcca agagggccag ctgcctttgc   1080

tatttaatac acttaatagt cactcttctc catttacagc tgtgctacta cttgtcactt   1140

tgggatccct tgcaattatc ttaacaagtc taattgattt gataaactat atttttttca   1200

cgggttcatt atggtctata ttattaatga taggaatact aaggcggaga taccaggaac   1260

ccaatctatc tataccttat aaggtgtttt tgtcatttcc attagcaaca atagtcatcg   1320

acgtgggctt ggttgtgata ccattggtaa agtctccaaa tgtgcattat gtctacgtgc   1380

ttctgttagt tctcagcgga ttactatttt acataccttt aatacatttt aaaataagat   1440

tggcttggtt tgagaagatg acttgctatt tacaattact atttaatatt tgcctccctg   1500

atgtgtctga ggaatagatg tcggaagtgc aaactcttaa aaaattggcc ttctaaaaaa   1560

catatatcag attccaaatc aaggttaaac atatgataga acattcatgg tgaaattcct   1620

atggtaaata tttttttctc aaatgaaata agtaatgtat acaaaagtgc ctaagacagt   1680

acctggcttc agagtcacta agaaattgct aaaagctctg cttcgcatgg taaaaaactt   1740

aagtcctggt ttgcgtagct tgatagagtg attatacaac ttccattctc tcactttttt   1800

tttctgtatc ccaccccttt tctactgaat ttgtggggat cctataataa aagtgaatga   1860

ctaaaaattt taaaagc                                                  1877


<210>  5947
<211>  470
<212>  PRT
<213>  Homo sapiens

<400>  5947

Met Asp Arg Gly Glu Lys Ile Gln Leu Lys Arg Val Phe Gly Tyr Trp 
1               5                   10                  15


Trp Gly Thr Ser Phe Leu Leu Ile Asn Ile Ile Gly Ala Gly Ile Phe 
            20                  25                  30


Val Ser Pro Lys Gly Val Leu Ala Tyr Ser Cys Met Asn Val Gly Val 
        35                  40                  45


Ser Leu Cys Val Trp Ala Gly Cys Ala Ile Leu Ala Met Thr Ser Thr 
    50                  55                  60


Leu Cys Ser Ala Glu Ile Ser Ile Ser Phe Pro Cys Ser Gly Ala Gln 
65                  70                  75                  80


Tyr Tyr Phe Leu Lys Arg Tyr Phe Gly Ser Thr Val Ala Phe Leu Asn 
                85                  90                  95


Leu Trp Thr Ser Leu Phe Leu Gly Ser Gly Val Val Ala Gly Gln Ala 
            100                 105                 110


Leu Leu Leu Ala Glu Tyr Ser Ile Gln Pro Phe Phe Pro Ser Cys Ser 
        115                 120                 125


Val Pro Lys Leu Pro Lys Lys Cys Leu Ala Leu Ala Met Leu Trp Ile 
    130                 135                 140


Val Gly Ile Leu Thr Ser Arg Gly Val Lys Glu Val Thr Trp Leu Gln 
145                 150                 155                 160


Ile Ala Ser Ser Val Leu Lys Val Ser Ile Leu Ser Phe Ile Ser Leu 
                165                 170                 175


Thr Gly Val Val Phe Leu Ile Arg Gly Lys Lys Glu Asn Val Glu Arg 
            180                 185                 190


Phe Gln Asn Ala Phe Asp Ala Glu Leu Pro Asp Ile Ser His Leu Ile 
        195                 200                 205


Gln Ala Ile Phe Gln Gly Tyr Phe Ala Tyr Ser Gly Gly Ala Cys Phe 
    210                 215                 220


Thr Leu Ile Ala Gly Glu Leu Lys Lys Pro Arg Thr Thr Ile Pro Lys 
225                 230                 235                 240


Cys Ile Phe Thr Ala Leu Pro Leu Val Thr Val Val Tyr Leu Leu Val 
                245                 250                 255


Asn Ile Ser Tyr Leu Thr Val Leu Thr Pro Arg Glu Ile Leu Ser Ser 
            260                 265                 270


Asp Ala Val Ala Ile Thr Trp Ala Asp Arg Ala Phe Pro Ser Leu Ala 
        275                 280                 285


Trp Ile Met Pro Phe Ala Ile Ser Thr Ser Leu Phe Ser Asn Leu Leu 
    290                 295                 300


Ile Ser Ile Phe Lys Ser Ser Arg Pro Ile Tyr Leu Ala Ser Gln Glu 
305                 310                 315                 320


Gly Gln Leu Pro Leu Leu Phe Asn Thr Leu Asn Ser His Ser Ser Pro 
                325                 330                 335


Phe Thr Ala Val Leu Leu Leu Val Thr Leu Gly Ser Leu Ala Ile Ile 
            340                 345                 350


Leu Thr Ser Leu Ile Asp Leu Ile Asn Tyr Ile Phe Phe Thr Gly Ser 
        355                 360                 365


Leu Trp Ser Ile Leu Leu Met Ile Gly Ile Leu Arg Arg Arg Tyr Gln 
    370                 375                 380


Glu Pro Asn Leu Ser Ile Pro Tyr Lys Val Phe Leu Ser Phe Pro Leu 
385                 390                 395                 400


Ala Thr Ile Val Ile Asp Val Gly Leu Val Val Ile Pro Leu Val Lys 
                405                 410                 415


Ser Pro Asn Val His Tyr Val Tyr Val Leu Leu Leu Val Leu Ser Gly 
            420                 425                 430


Leu Leu Phe Tyr Ile Pro Leu Ile His Phe Lys Ile Arg Leu Ala Trp 
        435                 440                 445


Phe Glu Lys Met Thr Cys Tyr Leu Gln Leu Leu Phe Asn Ile Cys Leu 
    450                 455                 460


Pro Asp Val Ser Glu Glu 
465                 470


<210>  5948
<211>  856
<212>  DNA
<213>  Homo sapiens

<400>  5948
aattcttata gggggtctga tgggtcagac ctcagtggag ccagtctggt accttgaaga     60

ggatttcatt ttactaaatg tcaagagttt gattgttttt gttgatcata atttgacaag    120

caacatgggg cctcagagaa gactaagaac cctgaaggag ttgtctgaac ctcgagctaa    180

ggatcagcag gagctcattg aaagcctcct tgactttgag tttctcctct ggtagaattg    240

gggagctgaa gaagcccaga acaacaattc ccaaatgcat atttactgcg ttacctctgg    300

tgactgtagt ttatttactg gttaacattt cctatctgac tgttctgaca cccagggaaa    360

ttctctcttc agatgctgta gctatcacat gggctgatcg agcttttccc tcattagcat    420

ggattatgcc ttttgctatt tctacctcat tatttagcaa ccttctgatt tctatattta    480

aatcatcgag accaatatat cttgcaagcc aagagggcca gctgcctttg ctatttaata    540

cacttaatag tcactcttct ccatttacag ctgtgctact acttgtcact ttgggatccc    600

ttgcaattat cttaacaagt ctaattgatt tgataaacta tatttttttc acgggttcat    660

tatggtctat attattaatg ataggaatac taaggcggag ataccaggaa cccaatctat    720

ctatacctta taaggtaaaa ttggatttct aattcttttc tgtgtgaaat aacagatatt    780

gagtataact gtatttaaga ttataatcag agcatctata agtagatctt ctgaatactc    840

agttactgtg aaacac                                                    856


<210>  5949
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  5949

Met Gly Gln Thr Ser Val Glu Pro Val Trp Tyr Leu Glu Glu Asp Phe 
1               5                   10                  15


Ile Leu Leu Asn Val Lys Ser Leu Ile Val Phe Val Asp His Asn Leu 
            20                  25                  30


Thr Ser Asn Met Gly Pro Gln Arg Arg Leu Arg Thr Leu Lys Glu Leu 
        35                  40                  45


Ser Glu Pro Arg Ala Lys Asp Gln Gln Glu Leu Ile Glu Ser Leu Leu 
    50                  55                  60


Asp Phe Glu Phe Leu Leu Trp 
65                  70


<210>  5950
<211>  526
<212>  DNA
<213>  Homo sapiens

<400>  5950
aaggcacagt cataaataca gagggttttc agaaccacct cagagaagat gtttaaatcg     60

ctgacaaaag tcaacaaggt gaagcctata ggagagaaca atgagaatga acaaagttct    120

cgtcggaatg aagaaggctc tcacccaagt aatcagtctc agcaaaccac agcacaggaa    180

gaaaacaaag gtgaagagaa atctctcaaa accaagtcaa ctccagtcac gtctgaagag    240

ccacacacca acatacaaga caaactctcc aagaaaaatt cctctggaga tctgaccaca    300

aaccctgacc ctcaaaatgc agcagaacca actggaacag tgccagagca gaaggaaatg    360

gaccccggga aagaaggtcc aaacagccca caaaacaaac cgcctgcagc tcctgttata    420

aatgagtatg ccgatgccca gctacacaac ctggtgaaaa gaatgcgtca aagaacagcc    480

ctctacaaga aaaagttggt agagggagat ctctcctcac ccgaag                   526


<210>  5951
<211>  158
<212>  PRT
<213>  Homo sapiens

<400>  5951

Met Phe Lys Ser Leu Thr Lys Val Asn Lys Val Lys Pro Ile Gly Glu 
1               5                   10                  15


Asn Asn Glu Asn Glu Gln Ser Ser Arg Arg Asn Glu Glu Gly Ser His 
            20                  25                  30


Pro Ser Asn Gln Ser Gln Gln Thr Thr Ala Gln Glu Glu Asn Lys Gly 
        35                  40                  45


Glu Glu Lys Ser Leu Lys Thr Lys Ser Thr Pro Val Thr Ser Glu Glu 
    50                  55                  60


Pro His Thr Asn Ile Gln Asp Lys Leu Ser Lys Lys Asn Ser Ser Gly 
65                  70                  75                  80


Asp Leu Thr Thr Asn Pro Asp Pro Gln Asn Ala Ala Glu Pro Thr Gly 
                85                  90                  95


Thr Val Pro Glu Gln Lys Glu Met Asp Pro Gly Lys Glu Gly Pro Asn 
            100                 105                 110


Ser Pro Gln Asn Lys Pro Pro Ala Ala Pro Val Ile Asn Glu Tyr Ala 
        115                 120                 125


Asp Ala Gln Leu His Asn Leu Val Lys Arg Met Arg Gln Arg Thr Ala 
    130                 135                 140


Leu Tyr Lys Lys Lys Leu Val Glu Gly Asp Leu Ser Ser Pro 
145                 150                 155


<210>  5952
<211>  946
<212>  DNA
<213>  Homo sapiens

<400>  5952
cataaataca gagggttttc agaaccacct cagagaagat gtttaaatcg ctgacaaaag     60

tcaacaaggt gaagcctata ggagagaaca atgagaatga acaaagttct cgtcggaatg    120

aagaaggctc tcacccaagt aatcagtctc agcaaaccac agcacaggaa gaaaacaaag    180

gtgaagagaa atctctcaaa accaagtcaa ctccagtcac gtctgaagag ccacacacca    240

acatacaaga caaactctcc aagaaaaatt cctctggaga tctgaccaca aaccctgacc    300

ctcaaaatgc agcagaacca actggaacag tgccagagca gaaggaaatg gaccccggga    360

aagaaggtcc aaacagttga ccctagaaca acaagaattt gaactgtggt accacttatc    420

cctggatttt cttccttctc tgccatctgt gagacagcaa cacgatctct cctcttcttg    480

ctcctcctca gcctactcaa catgaggaca actggatgca gacctttctg atgatccact    540

tccacttagg caatagtaaa tatatggtct cttctttatg attttaataa cattttctct    600

tctctggctt gctttattgt aagaatgcag tatgtaacat gtataacatg aaatatgtac    660

ccatccatat gaacaagtaa ggcttctggc caacagtagg ctattagtag ttaagtttgg    720

gaggagtcaa aagtcatatg caattttcag ctacacagga ggtctagtgc ccctaacctc    780

tacatcattt atgggccaac tgtaatttgc aataaatttt gactgctaga aataataaga    840

aatattagtt tttatgatat ttattctttc ttatagtgta atttacatgt ccacaatagt    900

aaatttgaaa aatatcacaa aataaaagta aaaatgactt ataatc                   946


<210>  5953
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  5953

Met Phe Lys Ser Leu Thr Lys Val Asn Lys Val Lys Pro Ile Gly Glu 
1               5                   10                  15


Asn Asn Glu Asn Glu Gln Ser Ser Arg Arg Asn Glu Glu Gly Ser His 
            20                  25                  30


Pro Ser Asn Gln Ser Gln Gln Thr Thr Ala Gln Glu Glu Asn Lys Gly 
        35                  40                  45


Glu Glu Lys Ser Leu Lys Thr Lys Ser Thr Pro Val Thr Ser Glu Glu 
    50                  55                  60


Pro His Thr Asn Ile Gln Asp Lys Leu Ser Lys Lys Asn Ser Ser Gly 
65                  70                  75                  80


Asp Leu Thr Thr Asn Pro Asp Pro Gln Asn Ala Ala Glu Pro Thr Gly 
                85                  90                  95


Thr Val Pro Glu Gln Lys Glu Met Asp Pro Gly Lys Glu Gly Pro Asn 
            100                 105                 110


Ser 



<210>  5954
<211>  801
<212>  DNA
<213>  Homo sapiens

<400>  5954
agtgaggcag tggggggtta gcaagttgaa ggcagataat atggggctct gtgggccatc     60

atgaggactt cagcttttac ctcggcatga gatgggaaac cactggagaa tctagaggag    120

aaagggatga tctgcccttc aacaggatca tccaggctac tccggtgaat atagaccata    180

tgagggcaaa gattggaagc taggtgagca gttagaaggc tactgcaata gctatgtgag    240

agagatgaac taggagagta gcagtggaga tctgagatac ggcaaagtct agatataaca    300

caaaggaata gccgacagaa tttgcttttg gattggctgt attgtaggag agaaaaaata    360

gggtgcattt ttgggttgag caaagagaag aatgaagatt ccttgtactg agatggggaa    420

aactgcagga ggagtgggtc tgaaagaggc aagttggttg ccatgttgtg agcagccccc    480

ttgaaaggcc catgtgatga tgaattgaaa cctcctgtca acagccatgt gagtgaccta    540

ggaagcagat cctgcagccc agtcatgctt cagatgaggc atatctgagg cacagagagg    600

ttaagttggg gactgaagtg tggctccaga atctaagttt ctaactgcca tgctatggta    660

agtgagattg gtaagtgcac atgaggaact cgtgagcctc aaagtcattc atcaatgcag    720

cattcaatga tggcttacat gaaggtatag aggtaggctc atcactttta cccaaactca    780

aaaaactgaa tttttattaa g                                              801


<210>  5955
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5955

Met Lys Ile Pro Cys Thr Glu Met Gly Lys Thr Ala Gly Gly Val Gly 
1               5                   10                  15


Leu Lys Glu Ala Ser Trp Leu Pro Cys Cys Glu Gln Pro Pro 
            20                  25                  30


<210>  5956
<211>  761
<212>  DNA
<213>  Homo sapiens

<400>  5956
gggtgattac acagtggttc tcaaagtatg gacctccaac cagcagcatc agcagcatct     60

ggatacttgc tagaaatgga aattctctgg ccctattcca ggccttccaa gttggaaact    120

ttgtgatggg gcccagcact ctgtgtttta acaagccctc tagccttaag gaaaacaact    180

ctgaggactt ttgtcacgga cttgaaattc tcatctgtgc ttggacaaga ctctgaaaca    240

taccaactgt gtattttcct gcctttggta aatctggagc tattaactga ttctaaagaa    300

catttgactt aaaaagacta tggaaagccc aaagaataaa gggacacttg tcactggatt    360

gaaggcatat tctaatttag gacaatgtct tgagatcttt aacttaacta catttgcaaa    420

gacccaattt ccaagtaact ggaacattct agataatgaa gaccccagtg gattattatt    480

agcaaatgaa aactggatat caagaagggc aaaatcttca accttatcag cagaaagagt    540

ttatgtaaaa atataccaca tagaataact aaaaaaataa gcaagtgata ccttatctga    600

gctcaaaata tctgtttctt tgcaaatgga taaaggattt attatattat agcaccttga    660

ggacagagac tttatgtttc taactaccca tcccagcatc atctagttca ttcctatgct    720

gaacagcccc taacacattg cctaaataaa tactaacatt a                        761


<210>  5957
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  5957

Met Glu Ser Pro Lys Asn Lys Gly Thr Leu Val Thr Gly Leu Lys Ala 
1               5                   10                  15


Tyr Ser Asn Leu Gly Gln Cys Leu Glu Ile Phe Asn Leu Thr Thr Phe 
            20                  25                  30


Ala Lys Thr Gln Phe Pro Ser Asn Trp Asn Ile Leu Asp Asn Glu Asp 
        35                  40                  45


Pro Ser Gly Leu Leu Leu Ala Asn Glu Asn Trp Ile Ser Arg Arg Ala 
    50                  55                  60


Lys Ser Ser Thr Leu Ser Ala Glu Arg Val Tyr Val Lys Ile Tyr His 
65                  70                  75                  80


Ile Glu 



<210>  5958
<211>  2911
<212>  DNA
<213>  Homo sapiens

<400>  5958
gcgcagggga gaggccagcc caggcagccg ttgtcgggtt cgactggagg ggcgggggag     60

tcacctgcga gcggctgcgc tggcggccag cccgcccacc gcgtctggat cgcgccggct    120

gcgcggggct gcggacagca cacaccctgg aaggccccgg cggggaacgg gcagagtccg    180

cgccctgcgt ccgcgaccag gaggatcgga ccttcgcctt cgctgtcgcc gccgccgccg    240

cccgcggccg tcggggctat tagtgaaaga tggtggatcg cttggcaaac agtgaagcaa    300

atactagacg tataagtata gtggaaaact gttttggagc agctggtcaa cctttaacta    360

tacctggacg agttcttatt ggagaaggag tattgactaa gttgtgcagg aaaaagccca    420

aagcaaggca gtttttcttg tttaatgata ttcttgtata tggcaatatt gtcatccaga    480

agaaaaaata taacaaacaa catattattc ccctggaaaa tgtcactatt gattccatca    540

aagatgaggg agacttaagg aatggatggc taatcaagac accaactaaa tcttttgcag    600

tttatgctgc cactgctacg gagaaatcag aatggatgaa tcatataaat aaatgtgtta    660

ctgatttact ctccaaaagt gggaagacac ccagtaatga acatgctgct gtctgggttc    720

ctgactctga ggcaactgta tgtatgcgtt gtcagaaagc aaaattcaca cctgttaatc    780

gtcgccacca ttgccgcaaa tgtggttttg ttgtctgtgg gccctgctct gaaaagagat    840

ttcttcttcc cagccagtcc tctaagcctg tgcggatttg tgacttctgc tatgacctgc    900

tttctgctgg ggacatggcc acatgccagc ctgctagatc agactcttac agccagtcat    960

tgaagtctcc tttaaatgat atgtctgatg atgatgacga tgatgatagc agtgactaag   1020

gacacatttg ggagtattta atcaggtgtg gctatctgag aaatcaactt tgggggaaat   1080

gtaagattct gagctctctc tctgttttgt tctagccatg aatttgcctg agaaacttgt   1140

aacctatgtg cctcaatata ttccatagaa agtaggtccc cctgccttct cccactcctc   1200

acactcttct acagggatag gcttttgcaa atatatcaga taaatttttt gtttcttgtt   1260

tatttttagg ttattttctt ggaaggttgg gaaaagatgt ttgttttaac aggtcatgta   1320

ctacgttgtt gttttcattt ctgttataag taaaactaaa agcacagaat ggtgggaaag   1380

gggctataat gtggttcatt aataatgtta gcagcttttt tctaaccatc ctgtctaatg   1440

gttaagacac cagtaacaaa aacacatgat ttggaaatac tttggctttt tcatatacct   1500

agtggtgcct tatcataata gcactgttac atgaaataag cccctacctt cttactttct   1560

ggtttgttga aaaaatacac tggtgctctt tgaagtgata aaatgagtgt ttatgaatgg   1620

gtgtaattag gaaatacttc tcatctgaca gctacaaata actaagtttg gaggtatttt   1680

cactctatat gaataaatat ttttccataa aatagttgtg attatatttt tgttttatat   1740

aggtcccaaa ttataattgt caaatatata ttttaaatta ataaaagttg tcattcttag   1800

gaatttggtt tgaaatttat cagttataca gaattgtcat actgcattag cttctacctt   1860

tagtaagaca tattttttag gtataaattc ttatgcttta acattatttc tggattgaaa   1920

atcttataaa acccttgaaa ataaacagtc tcttttttac aaagcctgtg ttagagcaca   1980

gatttaccta ggcttgaaga tttggaagaa ataatatgta agaatggcct caaggcagac   2040

cactttaagt ttggctagac ttcatatcgt ggaagtattg tctatttcag tgtgaaacta   2100

tcttgaattt gcaaatatag tgttatattt tataaagttt tgtaaaatcc caaacaatat   2160

ttctattttt gtaaaacaat tgtatgtata atctgtattt gaaatcattt tgcaatctat   2220

ggaaatagag tagcaattgc tatttctaaa ttgtgaactt taagtcaatc tagatttatt   2280

ttgagaagta attgttcact ctttactttt gaggcagcca ttaggttgaa agtatatatt   2340

tatcatataa aacttgatgc gttttgcact actctttcca tttatatgct gcaaacaact   2400

acagtctttg aaatatggaa aatcagcagt ctaaagtttg ttttaaattc taaatttaaa   2460

aaatcttcaa atctgaatat accgcaaatg tcatgagaag tttgattcag taacttgtga   2520

tggaggattc tttggtatct tactgtttgg ttaaggcact aattttactt acctattaga   2580

ttttgaaagt atctgagata tacaaatctc cctgtaggaa atgtgaaaga aaagcacaac   2640

aaaactaggg ttttttgttc atttgcttgc ttttatgatt ttttttggtt tgttttaata   2700

tcaggtggat ttttgtttct aagcaatata tacataaaat caaccaacat atctgaaaag   2760

gatcatgaaa cctgagaaat gctaatggag atttgctggt acataggaat ctagcaaatt   2820

caggaaccaa ggggaaatgt tgtgagataa catttacatt gtcaaccttt attgactttg   2880

tttttacaat aaaaaatatt ttacaactta c                                  2911


<210>  5959
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  5959

Met Val Asp Arg Leu Ala Asn Ser Glu Ala Asn Thr Arg Arg Ile Ser 
1               5                   10                  15


Ile Val Glu Asn Cys Phe Gly Ala Ala Gly Gln Pro Leu Thr Ile Pro 
            20                  25                  30


Gly Arg Val Leu Ile Gly Glu Gly Val Leu Thr Lys Leu Cys Arg Lys 
        35                  40                  45


Lys Pro Lys Ala Arg Gln Phe Phe Leu Phe Asn Asp Ile Leu Val Tyr 
    50                  55                  60


Gly Asn Ile Val Ile Gln Lys Lys Lys Tyr Asn Lys Gln His Ile Ile 
65                  70                  75                  80


Pro Leu Glu Asn Val Thr Ile Asp Ser Ile Lys Asp Glu Gly Asp Leu 
                85                  90                  95


Arg Asn Gly Trp Leu Ile Lys Thr Pro Thr Lys Ser Phe Ala Val Tyr 
            100                 105                 110


Ala Ala Thr Ala Thr Glu Lys Ser Glu Trp Met Asn His Ile Asn Lys 
        115                 120                 125


Cys Val Thr Asp Leu Leu Ser Lys Ser Gly Lys Thr Pro Ser Asn Glu 
    130                 135                 140


His Ala Ala Val Trp Val Pro Asp Ser Glu Ala Thr Val Cys Met Arg 
145                 150                 155                 160


Cys Gln Lys Ala Lys Phe Thr Pro Val Asn Arg Arg His His Cys Arg 
                165                 170                 175


Lys Cys Gly Phe Val Val Cys Gly Pro Cys Ser Glu Lys Arg Phe Leu 
            180                 185                 190


Leu Pro Ser Gln Ser Ser Lys Pro Val Arg Ile Cys Asp Phe Cys Tyr 
        195                 200                 205


Asp Leu Leu Ser Ala Gly Asp Met Ala Thr Cys Gln Pro Ala Arg Ser 
    210                 215                 220


Asp Ser Tyr Ser Gln Ser Leu Lys Ser Pro Leu Asn Asp Met Ser Asp 
225                 230                 235                 240


Asp Asp Asp Asp Asp Asp Ser Ser Asp 
                245


<210>  5960
<211>  2999
<212>  DNA
<213>  Homo sapiens

<400>  5960
gcgcagggga gaggccagcc caggcagccg ttgtcgggtt cgactggagg ggcgggggag     60

tcacctgcga gcggctgcgc tggcggccag cccgcccacc gcgtctggat cgcgccggct    120

gcgcggggct gcggacagca cacaccctgg aaggccccgg cggggaacgg gcagagtccg    180

cgccctgcgt ccgcgaccag gaggatcgga ccttcgcctt cgctgtcgcc gccgccgccg    240

cccgcggccg tcggggctat tagtgaaaga tggtggatcg cttggcaaac agtgaagcaa    300

atactagacg tataagtata gtggaaaact gttttggagc agctggtcaa cctttaacta    360

tacctggacg agttcttatt ggagaaggag tattgactaa gttgtgcagg aaaaagccca    420

aagcaaggca gtttttcttg tttaatgata ttcttgtata tggcaatatt gtcatccaga    480

agaaaaaata taacaaacaa catattattc ccctggaaaa tgtcactatt gattccatca    540

aagatgaggg agacttaagg aatggatggc taatcaagac accaactaaa tcttttgcag    600

tttatgctgc cactgctacg gagaaatcag aatggatgaa tcatataaat aaatgtgtta    660

ctgatttact ctccaaaagt gggaagacac ccagtaatga acatgctgct gtctgggttc    720

ctgactctga ggcaactgta tgtatgcgtt gtcagaaagc aaaattcaca cctgttaatc    780

gtcgccacca ttgccgcaaa tgtggttttg ttgtctgtgg gccctgctct gaaaagagat    840

ttcttcttcc cagccagtcc tctaagcctg tgcggatttg tgacttctgc tatgacctgc    900

tttctgctgg ggacatggcc acatgccagc ctgctagatc agactcttac agccagtcat    960

tgaagtctcc tttaaatgat atgtctgatg atgatgacga tgatgatagc agtgactaag   1020

gacacatttg ggagtattta atcaggtgtg gctatctgag aaatcaactt tgggggaaat   1080

gtaagattct gagctctctc tctgttttgt tctagccatg aatttgcctg agaaacttgt   1140

aacctatgtg cctcaatata ttccatagaa agtaggtccc cctgccttct cccactcctc   1200

acactcttct acagggatag gcttttgcaa atatatcaga taaatttttt gtttcttgtt   1260

tatttttagg ttattttctt ggaaggttgg gaaaagatgt ttgttttaac aggtcatgta   1320

ctacgttgtt gttttcattt ctgttataag taaaactaaa agcacagaat ggtgggaaag   1380

gggctataat gtggttcatt aataatgtta gcagcttttt tctaaccatc ctgtctaatg   1440

gttaagacac cagtaacaaa aacacatgat ttggaaatac tttggctttt tcatatacct   1500

agtggtgcct tatcataata gcactgttac atgaaataag cccctacctt cttactttct   1560

ggtttgttga aaaaatacac tggtgctctt tgaagtgata aaatgagtgt ttatgaatgg   1620

gtgtaattag gaaatacttc tcatctgaca gctacaaata actaagtttg gaggtatttt   1680

cactctatat gaataaatat ttttccataa aatagttgtg attatatttt tgttttatat   1740

aggtcccaaa ttataattgt caaatatata ttttaaatta ataaaagttg tcattcttag   1800

gaatttggtt tgaaatttat cagttataca gaattgtcat actgcattag cttctacctt   1860

tagtaagaca tattttttag gtataaattc ttatgcttta acattatttc tggattgaaa   1920

atcttataaa acccttgaaa ataaacagtc tcttttttac aaagcctgtg ttagagcaca   1980

gatttaccta ggcttgaaga tttggaagaa ataatatgta agaatggcct caaggcagac   2040

cactttaagt ttggctagac ttcatatcgt ggaagtattg tctatttcag tgtgaaacta   2100

tcttgaattt gcaaatatag tgttatattt tataaagttt tgtaaaatcc caaacaatat   2160

ttctattttt gtaaaacaat tgtatgtata atctgtattt gaaatcattt tgcaatctat   2220

ggaaatagag tagcaattgc tatttctaaa ttgtgaactt taagtcaatc tagatttatt   2280

ttgagaagta attgttcact ctttactttt gaggcagcca ttaggttgaa agtatatatt   2340

tatcatataa aacttgatgc gttttgcact actctttcca tttatatgct gcaaacaact   2400

acagtctttg aaatatggaa aatcagcagt ctaaagtttg ttttaaattc taaatttaaa   2460

aaatcttcaa atctgaatat accgcaaatg tcatgagaag tttgattcag taacttgtga   2520

tggaggattc tttggtatct tactgtttgg ttaaggcact aattttactt acctattaga   2580

ttttgaaagt atctgagata tacaaatctc cctgtaggaa atgtgaaaga aaagcacaac   2640

aaaactaggg ttttttgttc atttgcttgc ttttatgatt ttttttggtt tgttttaata   2700

tcaggtggat ttttgtttct aagcaatata tacataaaat caaccaacat atctgaaaag   2760

gatcatgaaa cctgagaaat gctaatggag atttgctggt acataggaat ctagcaaatt   2820

caggaaccaa ggggaaatgt tgtgagataa catttacatt gtcaaccttt attgactttg   2880

tttttacaat aaaaaatatt ttacaactta ctttctgttc tctgtatatt gtgacttgag   2940

gatttacccc ctctgctaag ataataaaga tattatgcat attttgccta ataattcaa    2999


<210>  5961
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  5961

Met Val Asp Arg Leu Ala Asn Ser Glu Ala Asn Thr Arg Arg Ile Ser 
1               5                   10                  15


Ile Val Glu Asn Cys Phe Gly Ala Ala Gly Gln Pro Leu Thr Ile Pro 
            20                  25                  30


Gly Arg Val Leu Ile Gly Glu Gly Val Leu Thr Lys Leu Cys Arg Lys 
        35                  40                  45


Lys Pro Lys Ala Arg Gln Phe Phe Leu Phe Asn Asp Ile Leu Val Tyr 
    50                  55                  60


Gly Asn Ile Val Ile Gln Lys Lys Lys Tyr Asn Lys Gln His Ile Ile 
65                  70                  75                  80


Pro Leu Glu Asn Val Thr Ile Asp Ser Ile Lys Asp Glu Gly Asp Leu 
                85                  90                  95


Arg Asn Gly Trp Leu Ile Lys Thr Pro Thr Lys Ser Phe Ala Val Tyr 
            100                 105                 110


Ala Ala Thr Ala Thr Glu Lys Ser Glu Trp Met Asn His Ile Asn Lys 
        115                 120                 125


Cys Val Thr Asp Leu Leu Ser Lys Ser Gly Lys Thr Pro Ser Asn Glu 
    130                 135                 140


His Ala Ala Val Trp Val Pro Asp Ser Glu Ala Thr Val Cys Met Arg 
145                 150                 155                 160


Cys Gln Lys Ala Lys Phe Thr Pro Val Asn Arg Arg His His Cys Arg 
                165                 170                 175


Lys Cys Gly Phe Val Val Cys Gly Pro Cys Ser Glu Lys Arg Phe Leu 
            180                 185                 190


Leu Pro Ser Gln Ser Ser Lys Pro Val Arg Ile Cys Asp Phe Cys Tyr 
        195                 200                 205


Asp Leu Leu Ser Ala Gly Asp Met Ala Thr Cys Gln Pro Ala Arg Ser 
    210                 215                 220


Asp Ser Tyr Ser Gln Ser Leu Lys Ser Pro Leu Asn Asp Met Ser Asp 
225                 230                 235                 240


Asp Asp Asp Asp Asp Asp Ser Ser Asp 
                245


<210>  5962
<211>  2912
<212>  DNA
<213>  Homo sapiens

<400>  5962
ggaggggaga cgcgaaactt tccgggcgct tcctcccgcg gtcccggagc cgtcgcagcg     60

ccgggaggtg tcgtcgtcgc gggcggtggc ggccgacgcc atgttggggt ctgtgagaaa    120

cggggcgctc ccggccgctc ccctcgcgcc ggggccggcc cgcgggccag ttgccgccgc    180

cgtcccgcca gcccgggagc gagccgcgcc cgcccgtagg acgccgccgc cgccgcgggg    240

ggacgggggc cgccgggcta ttagtgaaag atggtggatc gcttggcaaa cagtgaagca    300

aatactagac gtataagtat agtggaaaac tgttttggag cagctggtca acctttaact    360

atacctggac gagttcttat tggagaagga gtattgacta agttgtgcag gaaaaagccc    420

aaagcaaggc agtttttctt gtttaatgat attcttgtat atggcaatat tgtcatccag    480

aagaaaaaat ataacaaaca acatattatt cccctggaaa atgtcactat tgattccatc    540

aaagatgagg gagacttaag gaatggatgg ctaatcaaga caccaactaa atcttttgca    600

gtttatgctg ccactgctac ggagaaatca gaatggatga atcatataaa taaatgtgtt    660

actgatttac tctccaaaag tgggaagaca cccagtaatg aacatgctgc tgtctgggtt    720

cctgactctg aggcaactgt atgtatgcgt tgtcagaaag caaaattcac acctgttaat    780

cgtcgccacc attgccgcaa atgtggtttt gttgtctgtg ggccctgctc tgaaaagaga    840

tttcttcttc ccagccagtc ctctaagcct gtgcggattt gtgacttctg ctatgacctg    900

ctttctgctg gggacatggc cacatgccag cctgctagat cagactctta cagccagtca    960

ttgaagtctc ctttaaatga tatgtctgat gatgatgacg atgatgatag cagtgactaa   1020

ggacacattt gggagtattt aatcaggtgt ggctatctga gaaatcaact ttgggggaaa   1080

tgtaagattc tgagctctct ctctgttttg ttctagccat gaatttgcct gagaaacttg   1140

taacctatgt gcctcaatat attccataga aagtaggtcc ccctgccttc tcccactcct   1200

cacactcttc tacagggata ggcttttgca aatatatcag ataaattttt tgtttcttgt   1260

ttatttttag gttattttct tggaaggttg ggaaaagatg tttgttttaa caggtcatgt   1320

actacgttgt tgttttcatt tctgttataa gtaaaactaa aagcacagaa tggtgggaaa   1380

ggggctataa tgtggttcat taataatgtt agcagctttt ttctaaccat cctgtctaat   1440

ggttaagaca ccagtaacaa aaacacatga tttggaaata ctttggcttt ttcatatacc   1500

tagtggtgcc ttatcataat agcactgtta catgaaataa gcccctacct tcttactttc   1560

tggtttgttg aaaaaataca ctggtgctct ttgaagtgat aaaatgagtg tttatgaatg   1620

ggtgtaatta ggaaatactt ctcatctgac agctacaaat aactaagttt ggaggtattt   1680

tcactctata tgaataaata tttttccata aaatagttgt gattatattt ttgttttata   1740

taggtcccaa attataattg tcaaatatat attttaaatt aataaaagtt gtcattctta   1800

ggaatttggt ttgaaattta tcagttatac agaattgtca tactgcatta gcttctacct   1860

ttagtaagac atatttttta ggtataaatt cttatgcttt aacattattt ctggattgaa   1920

aatcttataa aacccttgaa aataaacagt ctctttttta caaagcctgt gttagagcac   1980

agatttacct aggcttgaag atttggaaga aataatatgt aagaatggcc tcaaggcaga   2040

ccactttaag tttggctaga cttcatatcg tggaagtatt gtctatttca gtgtgaaact   2100

atcttgaatt tgcaaatata gtgttatatt ttataaagtt ttgtaaaatc ccaaacaata   2160

tttctatttt tgtaaaacaa ttgtatgtat aatctgtatt tgaaatcatt ttgcaatcta   2220

tggaaataga gtagcaattg ctatttctaa attgtgaact ttaagtcaat ctagatttat   2280

tttgagaagt aattgttcac tctttacttt tgaggcagcc attaggttga aagtatatat   2340

ttatcatata aaacttgatg cgttttgcac tactctttcc atttatatgc tgcaaacaac   2400

tacagtcttt gaaatatgga aaatcagcag tctaaagttt gttttaaatt ctaaatttaa   2460

aaaatcttca aatctgaata taccgcaaat gtcatgagaa gtttgattca gtaacttgtg   2520

atggaggatt ctttggtatc ttactgtttg gttaaggcac taattttact tacctattag   2580

attttgaaag tatctgagat atacaaatct ccctgtagga aatgtgaaag aaaagcacaa   2640

caaaactagg gttttttgtt catttgcttg cttttatgat tttttttggt ttgttttaat   2700

atcaggtgga tttttgtttc taagcaatat atacataaaa tcaaccaaca tatctgaaaa   2760

ggatcatgaa acctgagaaa tgctaatgga gatttgctgg tacataggaa tctagcaaat   2820

tcaggaacca aggggaaatg ttgtgagata acatttacat tgtcaacctt tattgacttt   2880

gtttttacaa taaaaaatat tttacaactt ac                                 2912


<210>  5963
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  5963

Met Leu Gly Ser Val Arg Asn Gly Ala Leu Pro Ala Ala Pro Leu Ala 
1               5                   10                  15


Pro Gly Pro Ala Arg Gly Pro Val Ala Ala Ala Val Pro Pro Ala Arg 
            20                  25                  30


Glu Arg Ala Ala Pro Ala Arg Arg Thr Pro Pro Pro Pro Arg Gly Asp 
        35                  40                  45


Gly Gly Arg Arg Ala Ile Ser Glu Arg Trp Trp Ile Ala Trp Gln Thr 
    50                  55                  60


Val Lys Gln Ile Leu Asp Val 
65                  70


<210>  5964
<211>  3000
<212>  DNA
<213>  Homo sapiens

<400>  5964
ggaggggaga cgcgaaactt tccgggcgct tcctcccgcg gtcccggagc cgtcgcagcg     60

ccgggaggtg tcgtcgtcgc gggcggtggc ggccgacgcc atgttggggt ctgtgagaaa    120

cggggcgctc ccggccgctc ccctcgcgcc ggggccggcc cgcgggccag ttgccgccgc    180

cgtcccgcca gcccgggagc gagccgcgcc cgcccgtagg acgccgccgc cgccgcgggg    240

ggacgggggc cgccgggcta ttagtgaaag atggtggatc gcttggcaaa cagtgaagca    300

aatactagac gtataagtat agtggaaaac tgttttggag cagctggtca acctttaact    360

atacctggac gagttcttat tggagaagga gtattgacta agttgtgcag gaaaaagccc    420

aaagcaaggc agtttttctt gtttaatgat attcttgtat atggcaatat tgtcatccag    480

aagaaaaaat ataacaaaca acatattatt cccctggaaa atgtcactat tgattccatc    540

aaagatgagg gagacttaag gaatggatgg ctaatcaaga caccaactaa atcttttgca    600

gtttatgctg ccactgctac ggagaaatca gaatggatga atcatataaa taaatgtgtt    660

actgatttac tctccaaaag tgggaagaca cccagtaatg aacatgctgc tgtctgggtt    720

cctgactctg aggcaactgt atgtatgcgt tgtcagaaag caaaattcac acctgttaat    780

cgtcgccacc attgccgcaa atgtggtttt gttgtctgtg ggccctgctc tgaaaagaga    840

tttcttcttc ccagccagtc ctctaagcct gtgcggattt gtgacttctg ctatgacctg    900

ctttctgctg gggacatggc cacatgccag cctgctagat cagactctta cagccagtca    960

ttgaagtctc ctttaaatga tatgtctgat gatgatgacg atgatgatag cagtgactaa   1020

ggacacattt gggagtattt aatcaggtgt ggctatctga gaaatcaact ttgggggaaa   1080

tgtaagattc tgagctctct ctctgttttg ttctagccat gaatttgcct gagaaacttg   1140

taacctatgt gcctcaatat attccataga aagtaggtcc ccctgccttc tcccactcct   1200

cacactcttc tacagggata ggcttttgca aatatatcag ataaattttt tgtttcttgt   1260

ttatttttag gttattttct tggaaggttg ggaaaagatg tttgttttaa caggtcatgt   1320

actacgttgt tgttttcatt tctgttataa gtaaaactaa aagcacagaa tggtgggaaa   1380

ggggctataa tgtggttcat taataatgtt agcagctttt ttctaaccat cctgtctaat   1440

ggttaagaca ccagtaacaa aaacacatga tttggaaata ctttggcttt ttcatatacc   1500

tagtggtgcc ttatcataat agcactgtta catgaaataa gcccctacct tcttactttc   1560

tggtttgttg aaaaaataca ctggtgctct ttgaagtgat aaaatgagtg tttatgaatg   1620

ggtgtaatta ggaaatactt ctcatctgac agctacaaat aactaagttt ggaggtattt   1680

tcactctata tgaataaata tttttccata aaatagttgt gattatattt ttgttttata   1740

taggtcccaa attataattg tcaaatatat attttaaatt aataaaagtt gtcattctta   1800

ggaatttggt ttgaaattta tcagttatac agaattgtca tactgcatta gcttctacct   1860

ttagtaagac atatttttta ggtataaatt cttatgcttt aacattattt ctggattgaa   1920

aatcttataa aacccttgaa aataaacagt ctctttttta caaagcctgt gttagagcac   1980

agatttacct aggcttgaag atttggaaga aataatatgt aagaatggcc tcaaggcaga   2040

ccactttaag tttggctaga cttcatatcg tggaagtatt gtctatttca gtgtgaaact   2100

atcttgaatt tgcaaatata gtgttatatt ttataaagtt ttgtaaaatc ccaaacaata   2160

tttctatttt tgtaaaacaa ttgtatgtat aatctgtatt tgaaatcatt ttgcaatcta   2220

tggaaataga gtagcaattg ctatttctaa attgtgaact ttaagtcaat ctagatttat   2280

tttgagaagt aattgttcac tctttacttt tgaggcagcc attaggttga aagtatatat   2340

ttatcatata aaacttgatg cgttttgcac tactctttcc atttatatgc tgcaaacaac   2400

tacagtcttt gaaatatgga aaatcagcag tctaaagttt gttttaaatt ctaaatttaa   2460

aaaatcttca aatctgaata taccgcaaat gtcatgagaa gtttgattca gtaacttgtg   2520

atggaggatt ctttggtatc ttactgtttg gttaaggcac taattttact tacctattag   2580

attttgaaag tatctgagat atacaaatct ccctgtagga aatgtgaaag aaaagcacaa   2640

caaaactagg gttttttgtt catttgcttg cttttatgat tttttttggt ttgttttaat   2700

atcaggtgga tttttgtttc taagcaatat atacataaaa tcaaccaaca tatctgaaaa   2760

ggatcatgaa acctgagaaa tgctaatgga gatttgctgg tacataggaa tctagcaaat   2820

tcaggaacca aggggaaatg ttgtgagata acatttacat tgtcaacctt tattgacttt   2880

gtttttacaa taaaaaatat tttacaactt actttctgtt ctctgtatat tgtgacttga   2940

ggatttaccc cctctgctaa gataataaag atattatgca tattttgcct aataattcaa   3000


<210>  5965
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  5965

Met Leu Gly Ser Val Arg Asn Gly Ala Leu Pro Ala Ala Pro Leu Ala 
1               5                   10                  15


Pro Gly Pro Ala Arg Gly Pro Val Ala Ala Ala Val Pro Pro Ala Arg 
            20                  25                  30


Glu Arg Ala Ala Pro Ala Arg Arg Thr Pro Pro Pro Pro Arg Gly Asp 
        35                  40                  45


Gly Gly Arg Arg Ala Ile Ser Glu Arg Trp Trp Ile Ala Trp Gln Thr 
    50                  55                  60


Val Lys Gln Ile Leu Asp Val 
65                  70


<210>  5966
<211>  1416
<212>  DNA
<213>  Homo sapiens

<400>  5966
ggctattagt gaaagatggt ggatcgcttg gcaaacagtg aagcaaatac tagacgtata     60

agtatagtgg aaaactgttt tggagcagct ggtcaacctt taactatacc tggacgagtt    120

cttattggag aaggagtatt gactaagttg tgcaggaaaa agcccaaagc aaggcagttt    180

ttcttgttta atgatattct tgtatatggc aatattgtca tccagaagaa aaaatataac    240

aaacaacata ttattcccct ggaaaatgtc actattgatt ccatcaaaga tgagggagac    300

ttaaggaatg gatggctaat caagacacca actaaatctt ttgcagttta tgctgccact    360

gctacggaga aatcagaatg gatgaatcat ataaataaat gtgttactga tttactctcc    420

aaaagtggga agacacccag taatgaacat gctgctgtct gggttcctga ctctgaggca    480

actgtatgta tgcgttgtca gaaagcaaaa ttcacacctg ttaatcgtcg ccaccattgc    540

cgcaaatgtg gttttgttgt ctgtgggccc tgctctgaaa agagatttct tcttcccagc    600

cagtcctcta agcctgtgcg gatttgtgac ttctgctatg acctgctttc tgctggggac    660

atggccacat gccagcctgc tagatcagac tcttacagcc agtcattgaa gtctccttta    720

aatgatatgt ctgatgatga tgacgatgat gatagcagtg actaaggaca catttgggag    780

tatttaatca ggtgtggcta tctgagaaat caactttggg ggaaatgtaa gattctgagc    840

tctctctctg ttttgttcta gccatgaatt tgcctgagaa acttgtaacc tatgtgcctc    900

aatatattcc atagaaagta ggtccccctg ccttctccca ctcctcacac tcttctacag    960

ggataggctt ttgcaaatat atcagataaa ttttttgttt cttgtttatt tttaggttat   1020

tttcttggaa ggttgggaaa agatgtttgt tttaacaggt catgtactac gttgttgttt   1080

tcatttctgt tataatatct gagatataca aatctccctg taggaaatgt gaaagaaaag   1140

cacaacaaaa ctagggtttt ttgttcattt gcttgctttt atgatttttt ttggtttgtt   1200

ttaatatcag gtggattttt gtttctaagc aatatataca taaaatcaac caacatatct   1260

gaaaaggatc atgaaacctg agaaatgcta atggagattt gctggtacat aggaatctag   1320

caaattcagg aaccaagggg aaatgttgtg agataacatt tacattgtca acctttattg   1380

actttgtttt tacaataaaa aatattttac aactta                             1416


<210>  5967
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  5967

Met Tyr Tyr Val Val Val Phe Ile Ser Val Ile Ile Ser Glu Ile Tyr 
1               5                   10                  15


Lys Ser Pro Cys Arg Lys Cys Glu Arg Lys Ala Gln Gln Asn 
            20                  25                  30


<210>  5968
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  5968
acttgcaccc agagaaagag agagagagcc agagctgtcg gtctttgcag atggacaggg     60

ggagccagga cacagctcag cctactcatg cccagagaga gaaagagttc agctgctgac    120

cctgaaggca agggagagct ggccacgcag gtgtgtgtgg gagctggctg ctgagaggag    180

ccgccgagct ggagcaggca gccaaaataa aggtgaacag tgtaaacgag ctagtgtaag    240

ctgctgatga gagagctgct gaataaaatt acatttcacc tgcctacagc accccgagtg    300

ttctttcagc tatctgctca tccatcccct cttttcggac ctcagctggg actggacccc    360

aaccctgagc ataacaacaa gtgatacttt tgttaggtcc attttcactt catcagaaat    420

gtcctgagct ctccctgggc actgtcctgt ggctggtaag aggcagaggg caggaaccgt    480

gtcagtcttg ttccttgttg taacccagtg ccgggcacat gtgggccaaa taatcatggc    540

aacaggactt ttagaagcac gt                                             562


<210>  5969
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  5969

Met Arg Glu Leu Leu Asn Lys Ile Thr Phe His Leu Pro Thr Ala Pro 
1               5                   10                  15


Arg Val Phe Phe Gln Leu Ser Ala His Pro Ser Pro Leu Phe Gly Pro 
            20                  25                  30


Gln Leu Gly Leu Asp Pro Asn Pro Glu His Asn Asn Lys 
        35                  40                  45


<210>  5970
<211>  519
<212>  DNA
<213>  Homo sapiens

<400>  5970
gcgagcctcc caggattctc aaacagaagc agcctgccag gctgagccat ccagaagacc     60

ccctccctct tccctgagct ctgtttcttc catgaggttg aagaaaaatg ccgtcgtggt    120

cccctgcctg cttactcagc gtgtcaagca ggagttctca gctccagtgt gccatggagg    180

gccttgggaa gaggtcacat accattccca tccccaggca caggagcact gaggaccctt    240

cttgacctcc tggatcagaa aggcagagga aatgctgggc agaagtcaag gtgtcagtgg    300

gctgccctcc ctccggaggc tccaggggag aatctattcc tcgcctcttc caattgctgg    360

tggctgatgg cacaccttgg cttgtggcca caatactcca atttctgcct ccatggtcac    420

actgacttca tttcttctgt gtgcatcaaa tttctctctg ctctgtgatt gcatttaggg    480

cccctggatc agcaatgtca taaaagaccc cagttcttc                           519


<210>  5971
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  5971

Met Arg Leu Lys Lys Asn Ala Val Val Val Pro Cys Leu Leu Thr Gln 
1               5                   10                  15


Arg Val Lys Gln Glu Phe Ser Ala Pro Val Cys His Gly Gly Pro Trp 
            20                  25                  30


Glu Glu Val Thr Tyr His Ser His Pro Gln Ala Gln Glu His 
        35                  40                  45


<210>  5972
<211>  2532
<212>  DNA
<213>  Homo sapiens

<400>  5972
accggagcct tggcgattgg aggggaaaag gccaggcgat tcaagatggc ggaggacctg     60

gacgagctct tggatgaagt cgagtccaag ttttgcacac ctgaccttct aagacggggt    120

atggtcgagc agcccaaagg ctgcggcggc ggcacccaca gtagcgaccg gaaccaagcc    180

aaggcgaaag agacgctcag atcaacagaa acatttaaaa aagaagatga tcttgacagt    240

cttattaatg aaatacttga agagcccaac ttggacaaaa aaccctctaa attaaaatct    300

aaatcttcag gtaacacatc tgtcagagct tccattgaag gccttggtaa aagttgcagt    360

ccggtgtacc ttggtggaag ctctattcca tgtgggattg gaacaaatat ttcatggaga    420

gcatgtgacc atctgcgttg tatagcctgt gatttcttgg tagtcagcta tgatgactat    480

atgtgggaca aatcgtgtga ttatctgttt ttcaggaaca acatgccaga atttcacaaa    540

ttaaaagcaa agttgataaa gaagaaagga acacgggcat atgcctgcca gtgtagctgg    600

agaactattg aagaagtgac tgaccttcag acagatcatc agcttcgctg ggtttgtggt    660

aaacattaag aatgcagact gcacattcgg acagatgcat ccatgagagt ggtctccatg    720

aatcatcatc atgtttagac aatagtccct agcaatacca ttccctgtgg gaaaaggcag    780

tgaattttat tgatacaact acatacattt ttgaagacca aatggactaa ggaagatcat    840

gtattataac actttggaat tattcctgat acatggatgt ttcacttagt aacaggcatc    900

tacattcttt actaatctgt cttctgttta atagaggttt gattatggag ttccatacaa    960

atatctagtt tttcattagc aactgcaata ttgattgcta atacgtttag caaatcattc   1020

cccaacttgt agcagttaaa gtggataaag ccggccaggg caaagagatc atttaggggt   1080

gtctacaaca cttcttccag tcagatcttt tgttgccaaa gatcataatt tggacatggc   1140

agaaaccagg tgatcagtgg ctgactgaag ggtgttcaga agtagttaca ggtattttgc   1200

aaaaacactg cctcatagct gatcttacct catcaactca aagcaatgtt atgcacaata   1260

ttaaatacat gttaccagtt ttagcttatt tttccctctt ttgttcattt aactatcaaa   1320

agttattttc tattttgatt acccaataat atataaaaag agtttgatgc acccaaaatc   1380

acaaaaatcc taatacatac aggttattgt tggattttcc aagtactttc tatcctttaa   1440

tgcctaaaac tccatcaagg gaagtaaaca gcaagtaata taatttttca ggcagcctgt   1500

ggacttctct ggtaggatca ggttgacata tcgtttatta ggtgagtaag tgaaaagaca   1560

agtaaagcat aactgaacca acaggtaacc tgttgggctc cttcctgaca tcactgagat   1620

ctgaggagcc ctacaatagc agcacattca ggaaatcagg tccctcaaaa tttctagctc   1680

ccaaccccat tgagagattt tgggagcttt ccaatctgcc acaaactccc tgctacatat   1740

gtactatata gttcaaatgt gtgatacaga gcaccctgaa agggaataat tgaaacaaag   1800

ttataatctt cttagtctta tgctaaattt attccagcca ccctactgaa gggaggaaga   1860

tctgatcatt agaatccttt tcctagccat gacacattta catacttgta aaatttattg   1920

tagtaagtct agcattgcaa cagaatagat cttataatgg ccaatcctca cacttttgta   1980

ttaaggatat tatgacagac taaagcctac attgcctcta ctttgaaggg acaaagttgt   2040

cctggttttt ttttcccttt tattatttca ttataactat cctaaaactt acatacattg   2100

cctatgtttg gcattccata acataataat tataataatc ccccaatgtc agaaatgtat   2160

gtgtgagttc ccatgtttat tggcaattta taagcttttt aatattgtac tattttaaac   2220

taaaatgtag aaagaatatt atgtttatat acagtcagat aaattattaa ctgttgtaat   2280

ttaagctgaa aatgaaacta ttttagtatc agtatagaag aaaagtatag tttctaatca   2340

tctataattt taaaatgcaa agcctataaa actttcaaga tgttttgcct gtttgttttt   2400

aagatttata ataattttct atctttagca agtagctatt tttaagccag gtaacttctt   2460

tatttgaact gtattatact ctcagaccct catcctgcct agaaatgaat aagtaataaa   2520

taattactct gt                                                       2532


<210>  5973
<211>  207
<212>  PRT
<213>  Homo sapiens

<400>  5973

Met Ala Glu Asp Leu Asp Glu Leu Leu Asp Glu Val Glu Ser Lys Phe 
1               5                   10                  15


Cys Thr Pro Asp Leu Leu Arg Arg Gly Met Val Glu Gln Pro Lys Gly 
            20                  25                  30


Cys Gly Gly Gly Thr His Ser Ser Asp Arg Asn Gln Ala Lys Ala Lys 
        35                  40                  45


Glu Thr Leu Arg Ser Thr Glu Thr Phe Lys Lys Glu Asp Asp Leu Asp 
    50                  55                  60


Ser Leu Ile Asn Glu Ile Leu Glu Glu Pro Asn Leu Asp Lys Lys Pro 
65                  70                  75                  80


Ser Lys Leu Lys Ser Lys Ser Ser Gly Asn Thr Ser Val Arg Ala Ser 
                85                  90                  95


Ile Glu Gly Leu Gly Lys Ser Cys Ser Pro Val Tyr Leu Gly Gly Ser 
            100                 105                 110


Ser Ile Pro Cys Gly Ile Gly Thr Asn Ile Ser Trp Arg Ala Cys Asp 
        115                 120                 125


His Leu Arg Cys Ile Ala Cys Asp Phe Leu Val Val Ser Tyr Asp Asp 
    130                 135                 140


Tyr Met Trp Asp Lys Ser Cys Asp Tyr Leu Phe Phe Arg Asn Asn Met 
145                 150                 155                 160


Pro Glu Phe His Lys Leu Lys Ala Lys Leu Ile Lys Lys Lys Gly Thr 
                165                 170                 175


Arg Ala Tyr Ala Cys Gln Cys Ser Trp Arg Thr Ile Glu Glu Val Thr 
            180                 185                 190


Asp Leu Gln Thr Asp His Gln Leu Arg Trp Val Cys Gly Lys His 
        195                 200                 205


<210>  5974
<211>  2503
<212>  DNA
<213>  Homo sapiens

<400>  5974
aaaaggccag gcgattcaag atggcggagg acctggacga gctcttggat gaagtcgagt     60

ccaagttttg cacacctgac cttctaagac ggggtatggt cgagcagccc aaaggctgcg    120

gcggcggcac ccacagtagc gaccggaacc aagccaaggc gaaagagacg ctcagatcaa    180

cagaaacatt taaaaaagaa gatgatcttg acagtcttat taatgaaata cttgaagagc    240

ccaacttgga caaaaaaccc tctaaattaa aatctaaatc ttcaggtaac acatctgtca    300

gagcttccat tgaaggcctt ggtaaaagtt gcagtccggt gtaccttggt ggaagctcta    360

ttccatgtgg gattggaaca aatatttcat ggagagcatg tgaccatctg cgttgtatag    420

cctgtgattt cttggtagtc agctatgatg actatatgtg ggacaaatcg tgtgattatc    480

tgtttttcag gaacaacatg ccagaatttc acaaattaaa agcaaagttg ataaagaaga    540

aaggaacacg ggcatatgcc tgccagtgta gctggagaac tattgaagaa gtgactgacc    600

ttcagacaga tcatcagctt cgctgggttt gtggtaaaca ttaagaatgc agactgcaca    660

ttcggacaga tgcatccatg agagtggtct ccatgaatca tcatcatgtt tagacaatag    720

tccctagcaa taccattccc tgtgggaaaa ggcagtgaat tttattgata caactacata    780

catttttgaa gaccaaatgg actaaggaag atcatgtatt ataacacttt ggaattattc    840

ctgatacatg gatgtttcac ttagtaacag gcatctacat tctttactaa tctgtcttct    900

gtttaataga ggtttgatta tggagttcca tacaaatatc tagtttttca ttagcaactg    960

caatattgat tgctaatacg tttagcaaat cattccccaa cttgtagcag ttaaagtgga   1020

taaagccggc cagggcaaag agatcattta ggggtgtcta caacacttct tccagtcaga   1080

tcttttgttg ccaaagatca taatttggac atggcagaaa ccaggtgatc agtggctgac   1140

tgaagggtgt tcagaagtag ttacaggtat tttgcaaaaa cactgcctca tagctgatct   1200

tacctcatca actcaaagca atgttatgca caatattaaa tacatgttac cagttttagc   1260

ttatttttcc ctcttttgtt catttaacta tcaaaagtta ttttctattt tgattaccca   1320

ataatatata aaaagagttt gatgcaccca aaatcacaaa aatcctaata catacaggtt   1380

attgttggat tttccaagta ctttctatcc tttaatgcct aaaactccat caagggaagt   1440

aaacagcaag taatataatt tttcaggcag cctgtggact tctctggtag gatcaggttg   1500

acatatcgtt tattaggtga gtaagtgaaa agacaagtaa agcataactg aaccaacagg   1560

taacctgttg ggctccttcc tgacatcact gagatctgag gagccctaca atagcagcac   1620

attcaggaaa tcaggtccct caaaatttct agctcccaac cccattgaga gattttggga   1680

gctttccaat ctgccacaaa ctccctgcta catatgtact atatagttca aatgtgtgat   1740

acagagcacc ctgaaaggga ataattgaaa caaagttata atcttcttag tcttatgcta   1800

aatttattcc agccacccta ctgaagggag gaagatctga tcattagaat ccttttccta   1860

gccatgacac atttacatac ttgtaaaatt tattgtagta agtctagcat tgcaacagaa   1920

tagatcttat aatggccaat cctcacactt ttgtattaag gatattatga cagactaagc   1980

atggtagctc acgcctgtaa tcccagcact ttgggaggct gaggcaggca gatcagctga   2040

ggtcaggagt tcaagaccag cctggccaac atgataaaac accatctcta ctaaaaatac   2100

aaaaattagc tgggcgcggt ggtgcatgcc tgtaatccca actactcggg aggccgaggc   2160

aggaaaattt attgaacctg ggaggcagag gttgtagtga gccaaggtcg cgccactgcg   2220

ctccagcctg gacaacacag tgagactctg tctcaaaaaa aaaaaaaaga cattatgaca   2280

gattttatct tttaataaaa atgtattata tccctaaagt tatatctata tgtaattgag   2340

tcagaaacct agggggatgt cgattgaagt cgactgctgg aaaaaaatag cagagcaaca   2400

agatccacac atttagaacc tcatagaatt tgacacatta ttcataatgg tgcaattctt   2460

tcttttttat tccagtaagc aaatttacta aatcactaat ttg                     2503


<210>  5975
<211>  207
<212>  PRT
<213>  Homo sapiens

<400>  5975

Met Ala Glu Asp Leu Asp Glu Leu Leu Asp Glu Val Glu Ser Lys Phe 
1               5                   10                  15


Cys Thr Pro Asp Leu Leu Arg Arg Gly Met Val Glu Gln Pro Lys Gly 
            20                  25                  30


Cys Gly Gly Gly Thr His Ser Ser Asp Arg Asn Gln Ala Lys Ala Lys 
        35                  40                  45


Glu Thr Leu Arg Ser Thr Glu Thr Phe Lys Lys Glu Asp Asp Leu Asp 
    50                  55                  60


Ser Leu Ile Asn Glu Ile Leu Glu Glu Pro Asn Leu Asp Lys Lys Pro 
65                  70                  75                  80


Ser Lys Leu Lys Ser Lys Ser Ser Gly Asn Thr Ser Val Arg Ala Ser 
                85                  90                  95


Ile Glu Gly Leu Gly Lys Ser Cys Ser Pro Val Tyr Leu Gly Gly Ser 
            100                 105                 110


Ser Ile Pro Cys Gly Ile Gly Thr Asn Ile Ser Trp Arg Ala Cys Asp 
        115                 120                 125


His Leu Arg Cys Ile Ala Cys Asp Phe Leu Val Val Ser Tyr Asp Asp 
    130                 135                 140


Tyr Met Trp Asp Lys Ser Cys Asp Tyr Leu Phe Phe Arg Asn Asn Met 
145                 150                 155                 160


Pro Glu Phe His Lys Leu Lys Ala Lys Leu Ile Lys Lys Lys Gly Thr 
                165                 170                 175


Arg Ala Tyr Ala Cys Gln Cys Ser Trp Arg Thr Ile Glu Glu Val Thr 
            180                 185                 190


Asp Leu Gln Thr Asp His Gln Leu Arg Trp Val Cys Gly Lys His 
        195                 200                 205


<210>  5976
<211>  377
<212>  DNA
<213>  Homo sapiens

<400>  5976
gagtgaagag gtgccagaat ccgcgaagag ggtcgacgaa tgcgctgccg cggaggcaac     60

aatggccatg agggattcaa ggattatgcg tctctgcacc ctacaataca ccaactggca    120

gttccatcat ttgaaagaaa atcttcaagg taaagacatt tacaatgaca caaaaacctt    180

tcaaaggcat catggtccta aagggctttc cccaagggac agcacagtgt gttccaggcc    240

ctgacaagag gtttaagacc tgtgacacag actgaagctc tcctggcata ctctgaagct    300

ctcctggcac cctccccttt atgcttcaca ggtgtttctc ctaataaatt tcttgtatgt    360

ctcatcccat ctgggaa                                                   377


<210>  5977
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  5977

Met Ala Met Arg Asp Ser Arg Ile Met Arg Leu Cys Thr Leu Gln Tyr 
1               5                   10                  15


Thr Asn Trp Gln Phe His His Leu Lys Glu Asn Leu Gln Gly Lys Asp 
            20                  25                  30


Ile Tyr Asn Asp Thr Lys Thr Phe Gln Arg His His Gly Pro Lys Gly 
        35                  40                  45


Leu Ser Pro Arg Asp Ser Thr Val Cys Ser Arg Pro 
    50                  55                  60


<210>  5978
<211>  4705
<212>  DNA
<213>  Homo sapiens

<400>  5978
ctctccccct cccctcctca ctgtcacact ctctgtgccc ccgtctctct tctctcattt     60

gcttgctcat ctccgaacgt gaatccgcgg ctcccggagg agcccagcgc ccggagcacc    120

tggagtccgg ccggcggcgg gccgagcctg gccagcggcg gcggcggcgg cggcggcggc    180

gggagccgag ggagcggcag ccgcgaccgc gggcaccgcg ggagccccag cggcagcagc    240

cgccgccgag atgtcccggc gaaagcaaag caaaccccgg cagatcaaac ggccgcttga    300

agatgccatt gaagatgagg aagaagaatg tccatcagag gaaacagaca tcatctccaa    360

aggagacttt ccattggagg aaagcttttc cacagaattt gggcctgaaa atctgagctg    420

cgaagaagtg gaatactttt gtaacaaagg tgatgatgaa ggaatccagg agacagcaga    480

atcagatggg gacacacagt cagagaaacc ggggcaacct ggagttgaga cagacgactg    540

ggatggacca ggagagctgg aggtgtttca gaaagatggg gaacgaaaaa ttcagagtcg    600

acagcaactt ccagtgggaa caacctgggg gccgtttcct gggaagatgg acttgaataa    660

taattctttg aagacaaagg ctcaggtccc aatggtgctg actgctggtc ccaagtggtt    720

gctggatgtg acttggcaag gagtggaaga caacaaaaac aactgcattg tgtacagcaa    780

agggggtcag ctttggtgta caactacgaa ggccatctct gagggtgaag agctaattgc    840

ctttgtggtg gattttgact caaggctaca agctgccagt cagatgactc tcacagaagg    900

gatgtaccct gcacgcctgc tggactcaat tcagctgctt cctcagcaag ctgccatggc    960

ttctattttg cccacagcta ttgtcaataa ggatatattc ccttgcaagt cctgtggcat   1020

ctggtatcgg agtgagcgga atctgcaggc ccatttgatg tactactgca gtgggaggca   1080

aagagaagct gctccggtgt cagaggaaaa tgaagacagt gcccatcaga tttccagcct   1140

gtgccccttc ccacagtgca ccaagagctt ttcaaatgct cgagctctag aaatgcacct   1200

gaattcacac agtggagtga aaatggaaga attcctgccc cctggtgcta gtctaaaatg   1260

caccgtctgt agctacactg ctgattccgt gatcaacttt caccaacacc tgttctccca   1320

tctcactcaa gctgccttcc gatgtaatca ctgccatttc ggcttccaga ctcagaggga   1380

gttattgcag caccaggagc tccatgtccc tagcggcaaa cttcccagag aaagtgacat   1440

ggaacactct ccaagtgcaa ctgaagacag cttacagcca gccacagact tattgaccag   1500

aagcgaactt ccccagagcc aaaaggccat gcagactaaa gatgcgagct ctgacacaga   1560

gctggacaag tgtgagaaaa agactcagct ctttctcacg aaccagagac cagagataca   1620

gcctacaaca aataaacaaa gcttttctta cacaaaaata aagtctgagc cctctagccc   1680

aagacttgcc tcatctccag ttcagcctaa tattgggcct tctttccctg tgggcccttt   1740

cctatctcag ttttctttcc cccaagatat caccatggtc cctcaagctt cagagatctt   1800

agctaagatg tctgaactgg tgcatcggcg actgaggcat ggcagtagta gctaccctcc   1860

cgtcatttac agccctttga tgcccaaggg ggctacttgt tttgagtgta acataacatt   1920

caataatttg gataattatc tagtgcacaa aaagcattat tgcagcagcc gatggcagca   1980

gatggctaag tccccagagt tccctagtgt gtcagaaaag atgcctgaag ctttgagtcc   2040

caacactggc caaacctcca taaaccttct caacccagct gctcattctg ctgatcctga   2100

gaatccactt cttcaaacat cttgcatcaa ttcttccact gtcttagatt taattgggcc   2160

aaatgggaag ggccatgaca aggacttttc cactcaaact aagaagctct ccacctccag   2220

taacaatgat gacaaaatta atggaaaacc tgttgatgtg aaaaatccca gtgtcccctt   2280

agtggatggg gaaagtgacc caaataagac tacctgtgaa gcttgcaaca ttaccttcag   2340

ccggcacgaa acatacatgg tccacaaaca gtattactgt gctacacgcc acgaccctcc   2400

actgaagagg tctgcttcca acaaagtgcc tgccatgcag agaaccatgc gcacacgcaa   2460

gcgcagaaag atgtatgaga tgtgcctacc tgagcaggaa caaaggcctc cactggttca   2520

gcagagattt cttgacgtag ccaacctcaa taatccttgt acctccactc aagaacccac   2580

agaagggcta ggagagtgct accacccaag atgtgatatc tttccaggaa ttgtctctaa   2640

acacttggaa acttctctga cgatcaacaa gtgtgttcca gtttccaaat gtgatactac   2700

tcattccagt gtttcctgcc tagagatgga cgtgcccata gatctcagca aaaagtgttt   2760

atctcagtct gagcggacga ccacgtctcc caaaaggctg ctggactatc acgagtgcac   2820

tgtgtgcaag atcagtttca ataaggtaga aaactatctg gcccacaagc agaatttctg   2880

cccggttact gcacatcagc gtaatgacct gggtcaactg gacggcaaag tgtttccgaa   2940

tccagaaagc gaacgaaaca gccctgatgt cagctacgaa agaagcataa taaaatgtga   3000

gaaaaatggg aatttgaagc agccttcccc caatggaaac ttattttcat cccacctagc   3060

aaccctgcaa ggcttgaagg tctttagtga agctgctcag ctcattgcta caaaagaaga   3120

aaacagacat ttgtttcttc cacaatgcct ttaccctgga gcaataaaga aagcaaaagg   3180

agccgaccag ctttctccat attatggaat caagccaagt gattatattt ctggttctct   3240

tgtcatccat aacactgaca tcgagcaaag cagaaatgca gaaaatgaat ctcctaaagg   3300

ccaggcttcc tcaaatgggt gtgctgcgct gaagaaagat tctctgccat tgttgcccaa   3360

aaatcgagga atggtaatag tgaatggtgg actgaaacaa gatgagagac ctgctgccaa   3420

cccacagcaa gagaacattt cccagaatcc tcagcacgaa gacgaccaca aatctccctc   3480

gtggatctct gagaacccat tagctgccaa tgagaatgtc tcaccaggaa ttccctcagc   3540

agaggaacag ttgtctagta tagcaaaagg tgtgaatggt tccagccagg ctccaaccag   3600

tgggaaatat tgccggctat gtgatatcca gttcaacaac ctttcaaact ttataactca   3660

caagaagttt tattgctcat cacatgcagc agaacatgtc aaatgaacta actaaacatc   3720

agtcaccttt ggtatcagtg tttagtatgt tgttctaacc agtccagaaa aaaaaataag   3780

ctgtttgaat tacatctggg caatcaggag ataattcatt atggctgagt tgaagactta   3840

aggtgtaatt tcattacagt ccattagtaa agtgtattat tggtgccatt ttcaaaaaaa   3900

ttaatttatt ttaccagcag tattcatagc tgtggttatg ttatttttta tttaaaaact   3960

ttatattaaa gtcatttgta atgttattgt atagttattg tgtagcacat atggtttgca   4020

ctgtatagta gcttttaaag aaaatagtca caatacagaa aagcatttta gaaatagctt   4080

caaaagcact tgtgtatctt gattttttct tatatgctgt tgcagatata tgtatatgct   4140

aaaatataac ttgcaaagat gttctaaata cacatgctat aagttcgcct taagatttca   4200

attcttggat aatcaggctc tgtttgcact ttatatttta gcagatacag tctcttagtc   4260

actaggcttt gcatttgtat gtagctgtat gtttccgtcc attttcttaa tcctgaacct   4320

gtatgttaaa tgaagatggc aatttttttc ttgtatagta cttgtatttt ctttcgctga   4380

tgcagctctg tctcaatttt taaacctttg ctgttaaatg caatacttta taaagaatga   4440

acaaaattac tggaagcagt attgtaagta atgaggtagt attaatcagt tttatctttt   4500

gaaaggcaca gtctaaatcg aaaccctaaa ctcaatgctg caagtatgaa tttaattcat   4560

atataagatc tatttaaata taagagtagc aatactgcac ctggtgatca caaagataat   4620

gttctacttc tgatagaaat aatttctcaa caaatgttgt tactatgcat gtatatggat   4680

ggaataaaat tccagattgt tggag                                         4705


<210>  5979
<211>  1151
<212>  PRT
<213>  Homo sapiens

<400>  5979

Met Ser Arg Arg Lys Gln Ser Lys Pro Arg Gln Ile Lys Arg Pro Leu 
1               5                   10                  15


Glu Asp Ala Ile Glu Asp Glu Glu Glu Glu Cys Pro Ser Glu Glu Thr 
            20                  25                  30


Asp Ile Ile Ser Lys Gly Asp Phe Pro Leu Glu Glu Ser Phe Ser Thr 
        35                  40                  45


Glu Phe Gly Pro Glu Asn Leu Ser Cys Glu Glu Val Glu Tyr Phe Cys 
    50                  55                  60


Asn Lys Gly Asp Asp Glu Gly Ile Gln Glu Thr Ala Glu Ser Asp Gly 
65                  70                  75                  80


Asp Thr Gln Ser Glu Lys Pro Gly Gln Pro Gly Val Glu Thr Asp Asp 
                85                  90                  95


Trp Asp Gly Pro Gly Glu Leu Glu Val Phe Gln Lys Asp Gly Glu Arg 
            100                 105                 110


Lys Ile Gln Ser Arg Gln Gln Leu Pro Val Gly Thr Thr Trp Gly Pro 
        115                 120                 125


Phe Pro Gly Lys Met Asp Leu Asn Asn Asn Ser Leu Lys Thr Lys Ala 
    130                 135                 140


Gln Val Pro Met Val Leu Thr Ala Gly Pro Lys Trp Leu Leu Asp Val 
145                 150                 155                 160


Thr Trp Gln Gly Val Glu Asp Asn Lys Asn Asn Cys Ile Val Tyr Ser 
                165                 170                 175


Lys Gly Gly Gln Leu Trp Cys Thr Thr Thr Lys Ala Ile Ser Glu Gly 
            180                 185                 190


Glu Glu Leu Ile Ala Phe Val Val Asp Phe Asp Ser Arg Leu Gln Ala 
        195                 200                 205


Ala Ser Gln Met Thr Leu Thr Glu Gly Met Tyr Pro Ala Arg Leu Leu 
    210                 215                 220


Asp Ser Ile Gln Leu Leu Pro Gln Gln Ala Ala Met Ala Ser Ile Leu 
225                 230                 235                 240


Pro Thr Ala Ile Val Asn Lys Asp Ile Phe Pro Cys Lys Ser Cys Gly 
                245                 250                 255


Ile Trp Tyr Arg Ser Glu Arg Asn Leu Gln Ala His Leu Met Tyr Tyr 
            260                 265                 270


Cys Ser Gly Arg Gln Arg Glu Ala Ala Pro Val Ser Glu Glu Asn Glu 
        275                 280                 285


Asp Ser Ala His Gln Ile Ser Ser Leu Cys Pro Phe Pro Gln Cys Thr 
    290                 295                 300


Lys Ser Phe Ser Asn Ala Arg Ala Leu Glu Met His Leu Asn Ser His 
305                 310                 315                 320


Ser Gly Val Lys Met Glu Glu Phe Leu Pro Pro Gly Ala Ser Leu Lys 
                325                 330                 335


Cys Thr Val Cys Ser Tyr Thr Ala Asp Ser Val Ile Asn Phe His Gln 
            340                 345                 350


His Leu Phe Ser His Leu Thr Gln Ala Ala Phe Arg Cys Asn His Cys 
        355                 360                 365


His Phe Gly Phe Gln Thr Gln Arg Glu Leu Leu Gln His Gln Glu Leu 
    370                 375                 380


His Val Pro Ser Gly Lys Leu Pro Arg Glu Ser Asp Met Glu His Ser 
385                 390                 395                 400


Pro Ser Ala Thr Glu Asp Ser Leu Gln Pro Ala Thr Asp Leu Leu Thr 
                405                 410                 415


Arg Ser Glu Leu Pro Gln Ser Gln Lys Ala Met Gln Thr Lys Asp Ala 
            420                 425                 430


Ser Ser Asp Thr Glu Leu Asp Lys Cys Glu Lys Lys Thr Gln Leu Phe 
        435                 440                 445


Leu Thr Asn Gln Arg Pro Glu Ile Gln Pro Thr Thr Asn Lys Gln Ser 
    450                 455                 460


Phe Ser Tyr Thr Lys Ile Lys Ser Glu Pro Ser Ser Pro Arg Leu Ala 
465                 470                 475                 480


Ser Ser Pro Val Gln Pro Asn Ile Gly Pro Ser Phe Pro Val Gly Pro 
                485                 490                 495


Phe Leu Ser Gln Phe Ser Phe Pro Gln Asp Ile Thr Met Val Pro Gln 
            500                 505                 510


Ala Ser Glu Ile Leu Ala Lys Met Ser Glu Leu Val His Arg Arg Leu 
        515                 520                 525


Arg His Gly Ser Ser Ser Tyr Pro Pro Val Ile Tyr Ser Pro Leu Met 
    530                 535                 540


Pro Lys Gly Ala Thr Cys Phe Glu Cys Asn Ile Thr Phe Asn Asn Leu 
545                 550                 555                 560


Asp Asn Tyr Leu Val His Lys Lys His Tyr Cys Ser Ser Arg Trp Gln 
                565                 570                 575


Gln Met Ala Lys Ser Pro Glu Phe Pro Ser Val Ser Glu Lys Met Pro 
            580                 585                 590


Glu Ala Leu Ser Pro Asn Thr Gly Gln Thr Ser Ile Asn Leu Leu Asn 
        595                 600                 605


Pro Ala Ala His Ser Ala Asp Pro Glu Asn Pro Leu Leu Gln Thr Ser 
    610                 615                 620


Cys Ile Asn Ser Ser Thr Val Leu Asp Leu Ile Gly Pro Asn Gly Lys 
625                 630                 635                 640


Gly His Asp Lys Asp Phe Ser Thr Gln Thr Lys Lys Leu Ser Thr Ser 
                645                 650                 655


Ser Asn Asn Asp Asp Lys Ile Asn Gly Lys Pro Val Asp Val Lys Asn 
            660                 665                 670


Pro Ser Val Pro Leu Val Asp Gly Glu Ser Asp Pro Asn Lys Thr Thr 
        675                 680                 685


Cys Glu Ala Cys Asn Ile Thr Phe Ser Arg His Glu Thr Tyr Met Val 
    690                 695                 700


His Lys Gln Tyr Tyr Cys Ala Thr Arg His Asp Pro Pro Leu Lys Arg 
705                 710                 715                 720


Ser Ala Ser Asn Lys Val Pro Ala Met Gln Arg Thr Met Arg Thr Arg 
                725                 730                 735


Lys Arg Arg Lys Met Tyr Glu Met Cys Leu Pro Glu Gln Glu Gln Arg 
            740                 745                 750


Pro Pro Leu Val Gln Gln Arg Phe Leu Asp Val Ala Asn Leu Asn Asn 
        755                 760                 765


Pro Cys Thr Ser Thr Gln Glu Pro Thr Glu Gly Leu Gly Glu Cys Tyr 
    770                 775                 780


His Pro Arg Cys Asp Ile Phe Pro Gly Ile Val Ser Lys His Leu Glu 
785                 790                 795                 800


Thr Ser Leu Thr Ile Asn Lys Cys Val Pro Val Ser Lys Cys Asp Thr 
                805                 810                 815


Thr His Ser Ser Val Ser Cys Leu Glu Met Asp Val Pro Ile Asp Leu 
            820                 825                 830


Ser Lys Lys Cys Leu Ser Gln Ser Glu Arg Thr Thr Thr Ser Pro Lys 
        835                 840                 845


Arg Leu Leu Asp Tyr His Glu Cys Thr Val Cys Lys Ile Ser Phe Asn 
    850                 855                 860


Lys Val Glu Asn Tyr Leu Ala His Lys Gln Asn Phe Cys Pro Val Thr 
865                 870                 875                 880


Ala His Gln Arg Asn Asp Leu Gly Gln Leu Asp Gly Lys Val Phe Pro 
                885                 890                 895


Asn Pro Glu Ser Glu Arg Asn Ser Pro Asp Val Ser Tyr Glu Arg Ser 
            900                 905                 910


Ile Ile Lys Cys Glu Lys Asn Gly Asn Leu Lys Gln Pro Ser Pro Asn 
        915                 920                 925


Gly Asn Leu Phe Ser Ser His Leu Ala Thr Leu Gln Gly Leu Lys Val 
    930                 935                 940


Phe Ser Glu Ala Ala Gln Leu Ile Ala Thr Lys Glu Glu Asn Arg His 
945                 950                 955                 960


Leu Phe Leu Pro Gln Cys Leu Tyr Pro Gly Ala Ile Lys Lys Ala Lys 
                965                 970                 975


Gly Ala Asp Gln Leu Ser Pro Tyr Tyr Gly Ile Lys Pro Ser Asp Tyr 
            980                 985                 990


Ile Ser Gly Ser Leu Val Ile His Asn Thr Asp Ile Glu Gln Ser Arg 
        995                 1000                1005


Asn Ala Glu Asn Glu Ser Pro Lys Gly Gln Ala Ser Ser Asn Gly Cys 
    1010                1015                1020


Ala Ala Leu Lys Lys Asp Ser Leu Pro Leu Leu Pro Lys Asn Arg Gly 
1025                1030                1035                1040


Met Val Ile Val Asn Gly Gly Leu Lys Gln Asp Glu Arg Pro Ala Ala 
                1045                1050                1055


Asn Pro Gln Gln Glu Asn Ile Ser Gln Asn Pro Gln His Glu Asp Asp 
            1060                1065                1070


His Lys Ser Pro Ser Trp Ile Ser Glu Asn Pro Leu Ala Ala Asn Glu 
        1075                1080                1085


Asn Val Ser Pro Gly Ile Pro Ser Ala Glu Glu Gln Leu Ser Ser Ile 
    1090                1095                1100


Ala Lys Gly Val Asn Gly Ser Ser Gln Ala Pro Thr Ser Gly Lys Tyr 
1105                1110                1115                1120


Cys Arg Leu Cys Asp Ile Gln Phe Asn Asn Leu Ser Asn Phe Ile Thr 
                1125                1130                1135


His Lys Lys Phe Tyr Cys Ser Ser His Ala Ala Glu His Val Lys 
            1140                1145                1150


<210>  5980
<211>  1581
<212>  DNA
<213>  Homo sapiens

<400>  5980
ctgactggtg tgtttacaaa ccttgagcaa gatacagagt gccaattgct gtatttacaa     60

tcccttagct agacataaag gttctccaag tccccaccag actcaggagc ccagctggct    120

tcacccagtg gatcccgcat tggggcgcag gtggagctgc ctgccagtct cgtgctgtgc    180

gcccgcactc ctcagccctt gggtggtcga tgggactggg cgccgtagag caggcggcag    240

cgctcgtcgg ggaggctccg gctgcgcagg agcccacagc gtgggggagg ctcaggcatg    300

gtgggctgca ggtcccaagc cctgccccgc cgggaggcag ctaaggcccg gcgagaagtc    360

cggcacagca gctgctggcc caggtgctaa gcccctcact gcctagggcg ggcggggccg    420

gctggctggc cgctctgagt gcagggcccg tggagcccac gcccacccgg aactggcact    480

gacccgcaag cgctgtgcgc agccgcggtt cctgcccgcg cctctacttc cacacctccc    540

cgcaagctga gggagccggc tccggcctcg gccagcccag gaaggggctc caccgtgcag    600

cggcgggctg aagggctcct caagtgccgc caaagtggga gcccaggcag aggaggactc    660

gagaacgagc aagggctgcg agcgctgcca gcacgctgtc acctctcaat cccactcaaa    720

ctgtgtttac agagcatcag agaaaaaaag acaacctgta ttcgccctgg aaaaactaat    780

ggccgcttga agatgccatt gaagatgagg aagaagaatg tccatcagag gaaacagaca    840

tcatctccaa aggagacttt ccattggagg aaagcttttc cacagaattt gggcctgaaa    900

atctgagctg cgaagaagtg gaatactttt gtaacaaagg tgatgatgaa ggaatccagg    960

agacagcaga atcagatggg gacacacagt cagagaaacc ggggcaacct ggagttgaga   1020

cagacgactg ggatggacca ggagagctgg aggtgtttca gaaagatggg gaacgaaaaa   1080

ttcagagtcg acagcaactt ccagtgggaa caacctgggg gccgtttcct gggaagatgg   1140

acttgaataa taattctttg aagacaaagg ctcaggtccc aatggtgctg actgctggtc   1200

ccaagtggtt gctggatgtg acttggcaag gagtggaaga caacaaaaac aactgcattg   1260

tgtacagcaa agggggtcag ctttggtgta caactacgaa ggccatctct gagggtgaag   1320

agctaattgc ctttgtggtg gattttgact caaggctaca agctgccagt cagatgactc   1380

tcacagaagg gatgtaccct gcacgcctgc tggactcaat tcagctgctt cctcagcaag   1440

ctgccatggc ttctattttg cccacagcta ttgtcaatag taagtgctca gtgctgtgta   1500

gcccagcttt agaggtgatg ggaatttatg ggagaaaaaa atgtctactg acaagaaacc   1560

aggaacagac ctttttcctt c                                             1581


<210>  5981
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  5981

Met Asp Leu Asn Asn Asn Ser Leu Lys Thr Lys Ala Gln Val Pro Met 
1               5                   10                  15


Val Leu Thr Ala Gly Pro Lys Trp Leu Leu Asp Val Thr Trp Gln Gly 
            20                  25                  30


Val Glu Asp Asn Lys Asn Asn Cys Ile Val Tyr Ser Lys Gly Gly Gln 
        35                  40                  45


Leu Trp Cys Thr Thr Thr Lys Ala Ile Ser Glu Gly Glu Glu Leu Ile 
    50                  55                  60


Ala Phe Val Val Asp Phe Asp Ser Arg Leu Gln Ala Ala Ser Gln Met 
65                  70                  75                  80


Thr Leu Thr Glu Gly Met Tyr Pro Ala Arg Leu Leu Asp Ser Ile Gln 
                85                  90                  95


Leu Leu Pro Gln Gln Ala Ala Met Ala Ser Ile Leu Pro Thr Ala Ile 
            100                 105                 110


Val Asn Ser Lys Cys Ser Val Leu Cys Ser Pro Ala Leu Glu Val Met 
        115                 120                 125


Gly Ile Tyr Gly Arg Lys Lys Cys Leu Leu Thr Arg Asn Gln Glu Gln 
    130                 135                 140


Thr Phe Phe 
145


<210>  5982
<211>  630
<212>  DNA
<213>  Homo sapiens

<400>  5982
aggaataaag aatcacaaac ttgtccgctg acctcagcag gtggagtgcc ggaattcagg     60

ggaatctgtg ttatcatgca cactcttctc tgaggataga atcacaggca caccaaaaac    120

tagccatcgc cgttagggac ggcatcagaa gggacagccc caaaagatta cacaggacaa    180

aagaagtggt caaatacaag gattcctttg taagtggatg ctttaaatat attagtatat    240

tgagtaatcc tttatctagt tgctctcctc tgctggggac cagaaagttg ataagaaata    300

ttaaaaaaaa atttttttga aagggttgtg gttgtgcttg aaccaacttc agagttacat    360

attaggccta gtgtcatgga gacaaaacag aaatgcaatc tttggatact gcagctgctt    420

cgtgcttttg ccagcttatg ctgctaaaga aggagaaaaa aaaaggactg ccagagctaa    480

gaaaatttaa taccttggag ctgatatata cggtattatt ttgtcttttt gacagggtcc    540

ggtgctattt ttacccaagt tgatacaggg gttaggttag gactttagaa agaaatggtg    600

atttatttta agtactgttt gtgtaatagc                                     630


<210>  5983
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  5983

Met Gln Ser Leu Asp Thr Ala Ala Ala Ser Cys Phe Cys Gln Leu Met 
1               5                   10                  15


Leu Leu Lys Lys Glu Lys Lys Lys Gly Leu Pro Glu Leu Arg Lys Phe 
            20                  25                  30


Asn Thr Leu Glu Leu Ile Tyr Thr Val Leu Phe Cys Leu Phe Asp Arg 
        35                  40                  45


Val Arg Cys Tyr Phe Tyr Pro Ser 
    50                  55


<210>  5984
<211>  2479
<212>  DNA
<213>  Homo sapiens

<400>  5984
ctggaaactg cgacgagatg ggaactttct gaattaagca gcaattcccg cgctggtttt     60

ctggggagtc ctcgcctcca gagctagtta tgtatcaaat cccatttgca agggttgttt    120

gtcttgttca aaggacaatg ggtgtagccg atgtcaacag aagttgttct tcttccttcg    180

aagagaaggg atgcgccagt atggagagtg cctgcattcc tgcccatccg ggtactatgg    240

acaccgagcc ccagatatga acagatgtgc aagatgcaga atagaaaact gtgattcttg    300

ctttagcaaa gacttttgta ccaagtgcaa agtaggcttt tatttgcata gaggccgttg    360

ctttgatgaa tgtccagatg gttttgcacc attagaagaa accatggaat gtgtggaagg    420

atgtgaagtt ggtcattgga gcgaatgggg aacttgtagc agaaataatc gcacatgtgg    480

atttaaatgg ggtctggaaa ccagaacacg gcaaattgtt aaaaagccag tgaaagacac    540

aatactgtgt ccaaccattg ctgaatccag gagatgcaag atgacaatga ggcattgtcc    600

aggagggaag agaacaccaa aggcgaagga gaagaggaac aagaaaaaga aaaggaagct    660

gatagaaagg gcccaggagc aacacagcgt cttcctagct acagacagag ctaaccaata    720

aaacaagaga tccggtagat ttttaggggt ttttgttttt gcaaatgtgc acaaagctac    780

tctccactcc tgcacactgg tgtgcagcct ttgtgctgct ctgcccagta tctgttccca    840

gtaacatggt gaaaggaagc accaccagca tggcccctgt gttatttatg ctttgatttg    900

aatctggaga ctgtgaaggc aggagtaagt gcacagcccg tgacttggct cagtgtgtgc    960

tgagagaatc cgtccccggc accatggaca tgctagaggt gtgaggctgc agaacaccgc   1020

tggaggacgg acttgtgcct atttatgtga aagaagatgc ttggcaggca atgcgctact   1080

cactcgtgac ctttatttct cacattgtgc attttcaagg atatgtttgt gtggatatct   1140

gcttagtgtt accacatggt attctcagca tgttaccttc acactgttgt gcgatgaaac   1200

tgcttttagc tgaggatatg ctctggaaat tcctgctcag tttcactgca gccctaatat   1260

gtacatatac tgcaggagct acatataaag ctcttattta ctgtatattt atgctttctt   1320

gtgggtaaca agtcatacct gattaatatg atgccacttt gtttctagtg gttcctaacc   1380

cattgtctga taaatgactt ttctagtttg gggaattgac acttgttttg ttgcctcttg   1440

aaactttttt tttttcccct cattgtgggc ttatttctca ttgtaagggt aggataaact   1500

agtttttgta tatagagtca aatgaccagt gtcaaagagt ttgcatattg ggtagacctt   1560

ctccactcca catgtcccac acatatagat aaagcagcag gcggcatctg gcaatcagaa   1620

gcccaaactg cctttgagtc taagatgtga tgactttgat gaaacacaac tgaaaacatg   1680

agggactata tccagtcact tgtagccagt ttcacaggcc agctacagaa ttgtccaaac   1740

aaacattatt tctgactgca atttttttcc cccaaattta aagcaatccc tggctttaaa   1800

tgacaaggca cctaccaatg ttcttgggtc actgaagaag ctactaccat gagcctgggc   1860

atagaatttt aggagataaa aggatgaatt tctgtgactg ccagtcagat cttaacaggt   1920

ttctgttgag ccagaatctg tttcagatcc aagatggaga ggaacactat ggaaacttcc   1980

caggtgactt tcagagcagt tgtttcaaac acatcattgt ccttttaggg gaaccagttt   2040

ttagaaggtt gtgaattggc tttttcacaa agcatgatta tcttcctggc tgatccagga   2100

gaaaattaga acagaaaaat aatggttgtg gattttgaaa caaagcaagg taaagccttt   2160

tttttttcac cttgcattgg caaaactacc tcttcagtgt ttttaacttt tgattcaaaa   2220

gcatcttacc aataaggata aatatcatat acatcgttat gaaaatattg ctatgagata   2280

ataagccaca tatgaatgtt gtatacaact ttagggttta catttaatcc tgaagtgtta   2340

cctcctttca tgtctattta cactattttc ccatttacta agtggggagg gggtctcctt   2400

atatagtgct tcatcgttaa taagtcaata cctgttgttc ctgggatgtt cttttttgtg   2460

cattaaaaac ttcaaaatt                                                2479


<210>  5985
<211>  176
<212>  PRT
<213>  Homo sapiens

<400>  5985

Met Arg Gln Tyr Gly Glu Cys Leu His Ser Cys Pro Ser Gly Tyr Tyr 
1               5                   10                  15


Gly His Arg Ala Pro Asp Met Asn Arg Cys Ala Arg Cys Arg Ile Glu 
            20                  25                  30


Asn Cys Asp Ser Cys Phe Ser Lys Asp Phe Cys Thr Lys Cys Lys Val 
        35                  40                  45


Gly Phe Tyr Leu His Arg Gly Arg Cys Phe Asp Glu Cys Pro Asp Gly 
    50                  55                  60


Phe Ala Pro Leu Glu Glu Thr Met Glu Cys Val Glu Gly Cys Glu Val 
65                  70                  75                  80


Gly His Trp Ser Glu Trp Gly Thr Cys Ser Arg Asn Asn Arg Thr Cys 
                85                  90                  95


Gly Phe Lys Trp Gly Leu Glu Thr Arg Thr Arg Gln Ile Val Lys Lys 
            100                 105                 110


Pro Val Lys Asp Thr Ile Leu Cys Pro Thr Ile Ala Glu Ser Arg Arg 
        115                 120                 125


Cys Lys Met Thr Met Arg His Cys Pro Gly Gly Lys Arg Thr Pro Lys 
    130                 135                 140


Ala Lys Glu Lys Arg Asn Lys Lys Lys Lys Arg Lys Leu Ile Glu Arg 
145                 150                 155                 160


Ala Gln Glu Gln His Ser Val Phe Leu Ala Thr Asp Arg Ala Asn Gln 
                165                 170                 175


<210>  5986
<211>  3148
<212>  DNA
<213>  Homo sapiens

<400>  5986
agcctagact tagatgcctt ggaccacagc accacctact tatagaagca tcccaagcct     60

cagccggtct gcatctccat cggaaagtgc gcttgccaca tcccttcgga tcacttcgtc    120

ctcccgagag cgttctgcct tctacagctc ggaaagaaag aaatcttagc tgtgaagtga    180

ccgtggagaa agcgcaggaa gcgacacaat tggttaggga ggcagagagt gtgagcgggc    240

gcaccccttg cctggggacc gcgctcgcgg gcggggacgg agcatcccag tggctgcacc    300

cgccgctccg cgctcctgcc tggcgtcgcc aaccccgcgg cggccgctgg aattccagag    360

ctgccaggcg ctcccagccg gtctcggcaa acttttcccc agcccacgtg ctaaccaagc    420

ggctcgcttc ccgagcccgg gatggagcac cgcgcctagg gaggccgcgc cgcccgagac    480

gtgcgcacgg ttcgtggcgg agagatgctg atcgcgctga actgaccggt gcggcccggg    540

ggtgagtggc gagtctccct ctgagtcctc cccagcagcg cggccggcgc cggctctttg    600

ggcgaaccct ccagttccta gactttgaga ggcgtctctc ccccgcccga ccgcccagat    660

gcagtttcgc cttttctcct ttgccctcat cattctgaac tgcatggatt acagccactg    720

ccaaggcaac cgatggagac gcagtaagcg agctagttat gtatcaaatc ccatttgcaa    780

gggttgtttg tcttgttcaa aggacaatgg gtgtagccga tgtcaacaga agttgttctt    840

cttccttcga agagaaggga tgcgccagta tggagagtgc ctgcattcct gcccatccgg    900

gtactatgga caccgagccc cagatatgaa cagatgtgca agatgcagaa tagaaaactg    960

tgattcttgc tttagcaaag acttttgtac caagtgcaaa gtaggctttt atttgcatag   1020

aggccgttgc tttgatgaat gtccagatgg ttttgcacca ttagaagaaa ccatggaatg   1080

tgtggaagga tgtgaagttg gtcattggag cgaatgggga acttgtagca gaaataatcg   1140

cacatgtgga tttaaatggg gtctggaaac cagaacacgg caaattgtta aaaagccagt   1200

gaaagacaca atactgtgtc caaccattgc tgaatccagg agatgcaaga tgacaatgag   1260

gcattgtcca ggagggaaga gaacaccaaa ggcgaaggag aagaggaaca agaaaaagaa   1320

aaggaagctg atagaaaggg cccaggagca acacagcgtc ttcctagcta cagacagagc   1380

taaccaataa aacaagagat ccggtagatt tttaggggtt tttgtttttg caaatgtgca   1440

caaagctact ctccactcct gcacactggt gtgcagcctt tgtgctgctc tgcccagtat   1500

ctgttcccag taacatggtg aaaggaagca ccaccagcat ggcccctgtg ttatttatgc   1560

tttgatttga atctggagac tgtgaaggca ggagtaagtg cacagcccgt gacttggctc   1620

agtgtgtgct gagagaatcc gtccccggca ccatggacat gctagaggtg tgaggctgca   1680

gaacaccgct ggaggacgga cttgtgccta tttatgtgaa agaagatgct tggcaggcaa   1740

tgcgctactc actcgtgacc tttatttctc acattgtgca ttttcaagga tatgtttgtg   1800

tggatatctg cttagtgtta ccacatggta ttctcagcat gttaccttca cactgttgtg   1860

cgatgaaact gcttttagct gaggatatgc tctggaaatt cctgctcagt ttcactgcag   1920

ccctaatatg tacatatact gcaggagcta catataaagc tcttatttac tgtatattta   1980

tgctttcttg tgggtaacaa gtcatacctg attaatatga tgccactttg tttctagtgg   2040

ttcctaaccc attgtctgat aaatgacttt tctagtttgg ggaattgaca cttgttttgt   2100

tgcctcttga aacttttttt ttttcccctc attgtgggct tatttctcat tgtaagggta   2160

ggataaacta gtttttgtat atagagtcaa atgaccagtg tcaaagagtt tgcatattgg   2220

gtagaccttc tccactccac atgtcccaca catatagata aagcagcagg cggcatctgg   2280

caatcagaag cccaaactgc ctttgagtct aagatgtgat gactttgatg aaacacaact   2340

gaaaacatga gggactatat ccagtcactt gtagccagtt tcacaggcca gctacagaat   2400

tgtccaaaca aacattattt ctgactgcaa tttttttccc ccaaatttaa agcaatccct   2460

ggctttaaat gacaaggcac ctaccaatgt tcttgggtca ctgaagaagc tactaccatg   2520

agcctgggca tagaatttta ggagataaaa ggatgaattt ctgtgactgc cagtcagatc   2580

ttaacaggtt tctgttgagc cagaatctgt ttcagatcca agatggagag gaacactatg   2640

gaaacttccc aggtgacttt cagagcagtt gtttcaaaca catcattgtc cttttagggg   2700

aaccagtttt tagaaggttg tgaattggct ttttcacaaa gcatgattat cttcctggct   2760

gatccaggag aaaattagaa cagaaaaata atggttgtgg attttgaaac aaagcaaggt   2820

aaagcctttt ttttttcacc ttgcattggc aaaactacct cttcagtgtt tttaactttt   2880

gattcaaaag catcttacca ataaggataa atatcatata catcgttatg aaaatattgc   2940

tatgagataa taagccacat atgaatgttg tatacaactt tagggtttac atttaatcct   3000

gaagtgttac ctcctttcat gtctatttac actattttcc catttactaa gtggggaggg   3060

ggtctcctta tatagtgctt catcgttaat aagtcaatac ctgttgttcc tgggatgttc   3120

ttttttgtgc attaaaaact tcaaaatt                                      3148


<210>  5987
<211>  243
<212>  PRT
<213>  Homo sapiens

<400>  5987

Met Gln Phe Arg Leu Phe Ser Phe Ala Leu Ile Ile Leu Asn Cys Met 
1               5                   10                  15


Asp Tyr Ser His Cys Gln Gly Asn Arg Trp Arg Arg Ser Lys Arg Ala 
            20                  25                  30


Ser Tyr Val Ser Asn Pro Ile Cys Lys Gly Cys Leu Ser Cys Ser Lys 
        35                  40                  45


Asp Asn Gly Cys Ser Arg Cys Gln Gln Lys Leu Phe Phe Phe Leu Arg 
    50                  55                  60


Arg Glu Gly Met Arg Gln Tyr Gly Glu Cys Leu His Ser Cys Pro Ser 
65                  70                  75                  80


Gly Tyr Tyr Gly His Arg Ala Pro Asp Met Asn Arg Cys Ala Arg Cys 
                85                  90                  95


Arg Ile Glu Asn Cys Asp Ser Cys Phe Ser Lys Asp Phe Cys Thr Lys 
            100                 105                 110


Cys Lys Val Gly Phe Tyr Leu His Arg Gly Arg Cys Phe Asp Glu Cys 
        115                 120                 125


Pro Asp Gly Phe Ala Pro Leu Glu Glu Thr Met Glu Cys Val Glu Gly 
    130                 135                 140


Cys Glu Val Gly His Trp Ser Glu Trp Gly Thr Cys Ser Arg Asn Asn 
145                 150                 155                 160


Arg Thr Cys Gly Phe Lys Trp Gly Leu Glu Thr Arg Thr Arg Gln Ile 
                165                 170                 175


Val Lys Lys Pro Val Lys Asp Thr Ile Leu Cys Pro Thr Ile Ala Glu 
            180                 185                 190


Ser Arg Arg Cys Lys Met Thr Met Arg His Cys Pro Gly Gly Lys Arg 
        195                 200                 205


Thr Pro Lys Ala Lys Glu Lys Arg Asn Lys Lys Lys Lys Arg Lys Leu 
    210                 215                 220


Ile Glu Arg Ala Gln Glu Gln His Ser Val Phe Leu Ala Thr Asp Arg 
225                 230                 235                 240


Ala Asn Gln 



<210>  5988
<211>  666
<212>  DNA
<213>  Homo sapiens

<400>  5988
atggatcaaa ttcatttggt gaagcatcca gttactaaaa attttggtga gagtaacttt     60

acagaaaagc cgtaatgtag aattgcaaat ttagatattt ggggtaagaa ttatggtgat    120

tcttttgcga tcagttcctt gatgacctgg catctctagt tgatgccaat ctgttccaat    180

cttgacacca ccttggggct ccacttctgg ccaccttctt ctgttgaaat gccttcagat    240

tttcttccca ggactaccac ttaataacta tgtggacttg gacacatctc tgatactgtg    300

gagactgatt atggaactga tgttgcaggc tcgtgaggtt taacattacc tgacttcaca    360

atatgttaca agtccatggt aatccaaaca gcatgtattg ctgtaaaaac agacacatag    420

accaatggaa caaaatagtc cagaaataaa tccacagact tacagataac tgatttttca    480

gtacaagtgc taacaacata cactggggag aggagagcct cttcaataaa tggtgctggg    540

aaaattgaga atccatacgc agaaggatga aactggacct tgtctctccc catataaaaa    600

aaaaaaaaaa caactgaaga tggattaaag acttaaacta aggcctgaaa ccataaaact    660

actagt                                                               666


<210>  5989
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  5989

Met Pro Ile Cys Ser Asn Leu Asp Thr Thr Leu Gly Leu His Phe Trp 
1               5                   10                  15


Pro Pro Ser Ser Val Glu Met Pro Ser Asp Phe Leu Pro Arg Thr Thr 
            20                  25                  30


Thr 



<210>  5990
<211>  524
<212>  DNA
<213>  Homo sapiens

<400>  5990
agatgccttg gaccacagca ccacctactt atagaagcat cccaagcctc agccggtctg     60

catctccatc ggaaagtgcg cttgccacat cccttcggat cacttcgtcc tcccgagagc    120

gttctgcctt ctacagctcg gaaagaaaga aatcttagct gtgaagtgac cgtggagaaa    180

gcgcaggaag cgacacaatt ggttagggag gcagagagtg tgagcgggcg caccccttgc    240

ctggggaccg cgctcgcggg cggggacgga gcatcccagt ggctgcaccc gccgctccgc    300

gctcctgcct ggcgtcgcca accccgcggc ggccgctgga attccagagc tgccaggcgc    360

tcccagccgg tctcggcaaa cttttcccca gcccacgtgc taaccaagcg gctcgcttcc    420

cgagcccaga agggatgcgc cagtatggag agtgcctgca ttcctgccca tccgggtact    480

atggacaccg agccccagat atgaacagat gtgcaagtga gcat                     524


<210>  5991
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  5991

Met Pro Trp Thr Thr Ala Pro Pro Thr Tyr Arg Ser Ile Pro Ser Leu 
1               5                   10                  15


Ser Arg Ser Ala Ser Pro Ser Glu Ser Ala Leu Ala Thr Ser Leu Arg 
            20                  25                  30


Ile Thr Ser Ser Ser Arg Glu Arg Ser Ala Phe Tyr Ser Ser Glu Arg 
        35                  40                  45


Lys Lys Ser 
    50


<210>  5992
<211>  865
<212>  DNA
<213>  Homo sapiens

<400>  5992
acgccctgcg cgcgccgagc cgggagccgg ctgcctcgct ttgcgtgacc gcggcagctc     60

tccactgtgg tttgaatcca cggggtattg atcaccctgc ccatgctgaa ggtattaaac    120

tgcaaattga aggtgaaggt gtggaatctc aatccattaa aaataaaaat ttccagaagg    180

tgcctgacca gaaaggaact cccaagcgac tgcaggcaga agctgagacg gctaagtcag    240

ctacggtgaa gctatctaaa ccggtggctc tatggaccca gcaggatgtc tgcaagtggt    300

tgaagaaaca ttgtccgaat cagtatcaga tctacagtga gtcattcaaa cagcatgaca    360

taactgggcg agccctgctg agacttactg acaaaaagct cgagcgaatg gggattgccc    420

aggagaacct ccggcagcac atcttacaac aggtgctcca gctgaaggtg cgagaagaag    480

tcagaaatct acagttactc acacaagcat catctgaggg ttctccataa acacggttag    540

ccttccaagc tgctgtcctg ccagttgata tgaacatggc ctgttcctca cagaaagact    600

aacccatggc actgccagaa gatatccttg gatcgtggac agattaactg gattaactga    660

aaaaagcacc cattcagtca atattatggg ttttggaaaa atcttgcttt gctgtggatt    720

taaaatgagg tgcataatat aatgccaact cattccaagt ggtcattggc agaccattag    780

ctggaaaatt gcttccagtt ttcatcactg tgcataactc aagttccctt tggggagctg    840

tctgtgccct tcactagaag tcctg                                          865


<210>  5993
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  5993

Met Leu Lys Val Leu Asn Cys Lys Leu Lys Val Lys Val Trp Asn Leu 
1               5                   10                  15


Asn Pro Leu Lys Ile Lys Ile Ser Arg Arg Cys Leu Thr Arg Lys Glu 
            20                  25                  30


Leu Pro Ser Asp Cys Arg Gln Lys Leu Arg Arg Leu Ser Gln Leu Arg 
        35                  40                  45


<210>  5994
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  5994
gaatatttag gcgaaagcga gaggaagggg ggagcgcggg gcaggaggag tacctcggcc     60

aagaaaatta tgcatgcgtt agggaagctc tgagagaatg gctgtggaag ctctccactg    120

tggtttgaat ccacggggta ttgatcaccc tgcccatgct gaaggtatta aactgcaaat    180

tgaaggtgaa ggtgtggaat ctcaatccat taaaaataaa aatttccaga aggtgcctga    240

ccagaaagga actcccaagc gactgcaggc agaagctgag acggctaagg gcgagccctg    300

ctgagactta ctgacaaaaa gctcgagcga atggggattg cccaggagaa cctccggcag    360

cacatcttac aacaggtgct ccagctgaag gtgcgagaag aagtcagaaa tctacagtta    420

ctcacacaag gatattcagg aatatggaga tatccctgac tcttccaaaa gaatgaccaa    480

gatcatgcct aattacctcc atgtcctggg aaagccccgc tgtaatggag atggcatctt    540


<210>  5995
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  5995

Met Ala Val Glu Ala Leu His Cys Gly Leu Asn Pro Arg Gly Ile Asp 
1               5                   10                  15


His Pro Ala His Ala Glu Gly Ile Lys Leu Gln Ile Glu Gly Glu Gly 
            20                  25                  30


Val Glu Ser Gln Ser Ile Lys Asn Lys Asn Phe Gln Lys Val Pro Asp 
        35                  40                  45


Gln Lys Gly Thr Pro Lys Arg Leu Gln Ala Glu Ala Glu Thr Ala Lys 
    50                  55                  60


Gly Glu Pro Cys 
65


<210>  5996
<211>  673
<212>  DNA
<213>  Homo sapiens

<400>  5996
agattaataa cacacaggaa aaaccctcaa cttctttcat tcgcctgttg agataaaggg     60

aaagagagtc cccatccagg cctgcaggag agggagaact ggtggatgca aatgaaaaag    120

cagaggcatt cctcagagat tatagtgctg gagttggaag aagatgggag aaacatatga    180

ggagagaagg aagtcgagct cataccatga tgaagaagat aactcctgaa gattgggaag    240

ggcactggct ggctctcaaa gatggacaaa tggctttacg acgcttaagg ggatgctctg    300

tggagtctgc ttgggtgcaa atcaccacca tgacacacta cccaatgagc aaacaaaagc    360

aaactggtta aggatcctga caaagacttc gcagccagaa gaggcgatgc cgtgggtcaa    420

atctaggacc accagatttc aaaccttata cttctaatca ctatatgaca ctgaacatga    480

ttttaagaaa ctttcttaca aaaatgtatg aattggacaa gagagtaaca aaaacagagt    540

aattcactga tctctcattt tgtagatgta agttttgtat aatgagtttc catacatcag    600

gagacacttg gaaacataaa taagtcaaag ttacagacaa taaagttaca gagaattgta    660

ttattgtcct ctg                                                       673


<210>  5997
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  5997

Met Arg Arg Glu Gly Ser Arg Ala His Thr Met Met Lys Lys Ile Thr 
1               5                   10                  15


Pro Glu Asp Trp Glu Gly His Trp Leu Ala Leu Lys Asp Gly Gln Met 
            20                  25                  30


Ala Leu Arg Arg Leu Arg Gly Cys Ser Val Glu Ser Ala Trp Val Gln 
        35                  40                  45


Ile Thr Thr Met Thr His Tyr Pro Met Ser Lys Gln Lys Gln Thr Gly 
    50                  55                  60


<210>  5998
<211>  3066
<212>  DNA
<213>  Homo sapiens

<400>  5998
atatagtacc agatgttgca ccatctggat gatgtgtagg agataaagcc aaattgcaaa     60

aataaaagac tcatgatttc ccaaggaaag tcaactgtgc atggtggcta tcagacaaca    120

ccctagcaat gaatggggga acttgcagaa gaaagagtta atgcttgctt aaaccttccc    180

tggggagatt tgttcccagg ctttcacggc tttaacctca gcaaccctgt aagaaaattg    240

tgattcatat tttgatttgt tatcatagat gcaaagagac ataatttcat ggattctaag    300

atacacagag caagaagaga ttttgatcac ccagaacaac cacctgtctt tttagatcaa    360

gaagcagaag ctcagagcaa agaacatcac accacgtccc tcagtgattg aagcagtgat    420

tgagtcacag aataaatctg gaactcaggt cttctgatct ttgctccaga tgttagagac    480

aaaactaaaa gtaaaatacc aagtgaaatc aaagcatcac gattgagccc agaacatgaa    540

aaagaacttc ctggcccact tgagaaactg ttaaaccgga catacctttg gggacttctt    600

cccttctctg gaataagatt gatgtttcca tgctgtgaaa gacgatgatg ttccttctcc    660

cagattcctg catgtttgga ctggttcacc tttttggccc atcacttggg ctcattcagc    720

aacagtcatg ccttaggttg catcctcatc tataggccaa ttaaacaggg tttcttcttg    780

ataaatccct atggttttga ttttaggaag tcaggcatga tttcttttgg gatctatatg    840

acccaaagtg gccagtttta ccaaaggtgt ccctttgcac tgggatctct gggtctcatt    900

tgaacacagc ttgggtcctc ttgccttgtc ccagagaatc cccatgttgt caggacataa    960

gcagatactc tagggccttc accaaaagct acaaagaagc agacaggact caacttagga   1020

catcttatgg ttatgtaact aagagattat tttaggaagt aaacaggcct ctgttggctc   1080

aaatgaacat cttcattgtt agtttccact tacattgttc tcgggataaa tcggccagaa   1140

tttggcaggg ctccccagca gtccttgtga atccctgtgg taggatgttt cagttctcct   1200

gagtcaggct gaagtgaaag ctcctaagag atattcagaa agaaggatgg tcaagttcta   1260

gaacaacaat agttggccca gtaattttaa agattgtcat tctacctaag ccttcatcct   1320

ccagatagca ctgttatggg cttaaaataa gcttcaaggg aaataatgaa tttctttgac   1380

accgccaaaa atcggctgta tataagaata acttgagaat ggcttacaat gaggtagtca   1440

aaagcccagc tcagtgctca ggaatgtatt tgtaattcct cttagacttg tcgaatggac   1500

tgcaatttga tacctaagag taataaaaaa tgagaccata ttttatgtta atgttccctt   1560

ctcttcctct gcccacaaaa gtgaggtcag ggaaggggag agaaacttat cctaagcact   1620

ccttatgagt tgcttgtgac atgatagctc tctctaaagt tcatgcaatc ctcatcgcaa   1680

ccccatgagg gagatgttat tgtctccatc ttatagatga ggaaactgaa gacaagacct   1740

tgtcaaaggt cacacattgt aagaagtaga gctgcatatt caaccaaagc ccgtgtacct   1800

ggaaagctca ttctctctcc cccttcttcc tctcaaatca ggccctagct cctccacaat   1860

gcttcgggct tctacgttca ctcagcttta cagtaaaatg atcacagacc catgagttcc   1920

ctggagagta gagtgatgcc tgggtcagct gttcctcttg tctgttcagc aggtcctttg   1980

agtggcttca caatccagct gtcagtggca gaaaataatg cctcataaat tattcacctg   2040

gttcacattg gaatccatta gctctcgggg cttggtgtgg ctgcagatca tccacaagtg   2100

ccccttgttc tctgccccca aggagctcct gtcattgttt ttaaccaaac aagttcaaat   2160

atctccacgt ctctgctgac tctggtcttt tgtctctaga ctgtaccttt atttctgagc   2220

tctgaaattc tgcagaaaca ggtgagtcta taaaaacatt ctgtgggagg ccaaaagctc   2280

agaacagttg tgtctctctt tctcagtatt aaaagatcaa ggtttcccat ggaagccaac   2340

ctgatctggt aattgggccc ttctataccc ctctgaatac ttttccaagg agggggcagt   2400

tcccaccccc atagttcccc tgagggttaa gagtccaggt ggtggccaag ttgcaagatt   2460

tggggcagcc attttgccaa ggatcagaga tttgctgttg gagaggtgaa gtcggctctg   2520

tgccatcctg aaaaatcaac ttagaaagat aggtggactt catcagattt gtcagtcctt   2580

ccttgtttta aagagaaaaa tgatctctgc cttgcttcag ataggatatg gctatttttt   2640

ttccttcttt ttctaatgta gcagtgatgg aaaacaccag tctttgaaga acaaatggag   2700

gttcccagtg acatgaatcc attatatttg attttggatt gtatttttta accccttttt   2760

atggcataga attctggtgc cttgctccct gggtttgtct ctgtgctacg agtaggcttt   2820

cttcacattc tggcttacag gggaacacaa ctattccaca agtggccttt agtgctcttt   2880

ataatatgat ttcctgtaat ttttaaactg tatgtgtaat ttatattctg gctctgtcca   2940

atatttgaac aactttaata ggttgatttc catatatatt atgcaaataa ttcttacctg   3000

attttttatg ttctatctta aataaatact gcaccactta ttaataaata gacatttcag   3060

tgatta                                                              3066


<210>  5999
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  5999

Met Met Phe Leu Leu Pro Asp Ser Cys Met Phe Gly Leu Val His Leu 
1               5                   10                  15


Phe Gly Pro Ser Leu Gly Leu Ile Gln Gln Gln Ser Cys Leu Arg Leu 
            20                  25                  30


His Pro His Leu 
        35


<210>  6000
<211>  5593
<212>  DNA
<213>  Homo sapiens

<400>  6000
cggccgcgac gaggggcagc ggaggacccc gcagggcatc gggctcctgg ccaagacccc     60

gctgagccgc ccagtcaaga gaaacaacgc caagtaccgg cgcatccaaa ctttgatcta    120

cgacgccctg gagagaccgc ggggctgggc gctgctttac cacgcgttgg tgttcctgat    180

tgtcctgggg tgcttgattc tggctgtcct gaccacattc aaggagtatg agactgtctc    240

gggagactgg cttctgttac tggagacatt tgctattttc atctttggag ccgagtttgc    300

tttgaggatc tgggctgctg gatgttgctg ccgatacaaa ggctggcggg gccgactgaa    360

gtttgccagg aagcccctgt gcatgttgga catctttgtg ctgattgcct ctgtgccagt    420

ggttgctgtg ggaaaccaag gcaatgttct ggccacctcc ctgcgaagcc tgcgcttcct    480

gcagatcctg cgcatgctgc ggatggaccg gagaggtggc acctggaagc ttctgggctc    540

agccatctgt gcccacagca aagaactcat cacggcctgg tacatcggtt tcctgacact    600

catcctttct tcatttcttg tctacctggt tgagaaagac gtcccagagg tggatgcaca    660

aggagaggag atgaaagagg agtttgagac ctatgcagat gccctgtggt ggggcctgat    720

cacactggcc accattggct atggagacaa gacacccaaa acgtgggaag gccgtctgat    780

tgccgccacc ttttccttaa ttggcgtctc cttttttgcc cttccagcgg gcatcctggg    840

gtccgggctg gccctcaagg tgcaggagca acaccgtcag aagcactttg agaaaaggag    900

gaagccagct gctgagctca ttcaggctgc ctggaggtat tatgctacca accccaacag    960

gattgacctg gtggcgacat ggagatttta tgaatcagtc gtctcttttc ctttcttcag   1020

gcaaaacagc tggaggcagc atccagccaa aagctgggtc tcttggatcg ggttcgcctt   1080

tctaatcctc gtggtagcaa tactaaagga aagctattta cccctctgaa tgtagatgcc   1140

atagaagaaa gtccttctaa agaaccaaag cctgttggct taaacaataa agagcgtttc   1200

cgcacggcct tccgcatgaa agcctacgct ttctggcaga gttctgaagg taatgccttt   1260

ttatctccct ccctgtctct tccacttctt cctcccccaa gtccacttcc ttcctcacct   1320

ctccctttgc ccacttaaga acctttgact ccacaaggta actctctccc ttccctcgac   1380

aagccaactt cttgcttccc taactcctcc tgtcccttgg gctgaggcat tgtgatgtat   1440

tcccaggagt ctagggctgc aggctcccaa gttaggagcc tggaaacctg tcaccttggt   1500

ttctaagggt ccgccccgac cccccgcccc atgattggat tgttatggag gtcaacttga   1560

aggatggggc ggtgccaggt gcaaagcaat ttagagacca gggcacggga agagtggcag   1620

aaaagcgccc tctggaggct gtaggagcca tggcctcatg tgcctctttt acttatgcaa   1680

agggaggaca tgcagaaaag cctgtttcct cagtgtctga gcccacccag gccctcaatc   1740

ctcattgtat cattcagttc tctccaaggc ctctgatgtg acagtgtgtg ttgtttgctg   1800

gcttctgtgt cctttgctgg cttctggctc tgggggccac tctggaactg cggagctcac   1860

ttctcctccc tgctagcctt ttccctcact accagtcatg agctgcgcac acttttgact   1920

tggacttctg ggtaatagaa tgagggtgcc aagaaaggct gaacagcatc acagcttgag   1980

aataccgtgg agtcttgcaa cgtggaaata aagactctgg ggattgacac atccagaggc   2040

gtggaaggct ttgaccgaac agtggggtcc ccaagccttt tccaggtctg tggcctgccg   2100

ttcatatgtg tgtctccctc ccagatgccg ggacaggtga ccccatggcg gaagacaggg   2160

gctatgggaa tgacttcccc atcgaagaca tgatccccac cctgaaggcc gccatccgag   2220

ccgtcagaat tctacaattc cgtctctata aaaaaaaatt caaggagact ttgaggcctt   2280

acgatgtgaa ggatgtgatt gagcagtatt ctgccgggca tctcgacatg ctttccagga   2340

taaagtacct tcagacgaga atagatatga ttttcacccc tggacctccc tccacgccaa   2400

aacacaagaa gtctcagaaa gggtcagcat tcaccttccc atcccagcaa tctcccagga   2460

atgaaccata tgtagccaga ccatccacat cagaaatcga agaccaaagc atgatgggga   2520

agtttgtaaa agttgaaaga caggttcagg acatggggaa gaagctggac ttcctcgtgg   2580

atatgcacat gcaacacatg gaacggttgc aggtgcaggt cacggagtat tacccaacca   2640

agggcacctc ctcgccagct gaagcagaga agaaggagga caacaggtat tccgatttga   2700

aaaccatcat ctgcaactat tctgagacag gccccccgga accaccctac agcttccacc   2760

aggtgaccat tgacaaagtc agcccctatg ggttttttgc acatgaccct gtgaacctgc   2820

cccgaggggg acccagttct ggaaaggttc aggcaactcc tccttcctca gcaacaacgt   2880

atgtggagag gcccacggtc ctgcctatct tgactcttct cgactcccga gtgagctgcc   2940

actcccaggc tgacctgcag ggcccctact cggaccgaat ctccccccgg cagagacgta   3000

gcatcacgcg agacagtgac acacctctgt ccctgatgtc ggtcaaccac gaggagctgg   3060

agaggtctcc aagtggcttc agcatctccc aggacagaga tgattatgtg ttcggcccca   3120

atggggggtc gagctggatg agggagaagc ggtacctcgc cgagggtgag acggacacag   3180

acacggaccc cttcacgccc agcggctcca tgcctctgtc gtccacaggg gatgggattt   3240

ctgattcagt atggacccct tccaataagc ccatttaaaa gaggtcactg gctgacccct   3300

ccttgtaatg tagacagact ttgtatagtt cacttactct tacacccgac gcttaccagc   3360

ggggacacca atggctgcat caaatgcatg cgtgtgcgtg gtggccccac ccaggcaggg   3420

gcttcccaca gcctcttcct ccccatgtca ccacaacaaa gtgcttcctt ttcagcatgg   3480

tttgcatgac tttacactat ataaatggtt ccgctaatct cttctaggat acacatttat   3540

ctgctgttct tacttttaat cacgattgga ccagtacagg gagaaattac tgatgagcca   3600

tgctatttgt ctgtttggtt ggctggtttg ggttttggtt tggtaagcag agaaagtagt   3660

ttaagttatt tctaggatca ctgccctctt gtgtaaaacg ctccagcaat taactgtttt   3720

tgaaagcaag gaaataattt tctcaacaaa accacattgt gtatcagtgg ggctgcctac   3780

tgagctaaca ttaggaaagg aatgagatag tcattgtgtc tctaaaacaa agaatttaaa   3840

caaatattta aggcaaaacc ttttaaaagc tctccaaaag acctcacttg gcctgatgtt   3900

acttagtatc atgcctcagt ttccttatct gtaaaaagtg gtggtaatcc caagtgtagc   3960

atttctgatg agttatgaat tggcagggag aaaacacaca cacacacaca cacacacaca   4020

cacacacaca catacacaaa gttaaaatag tttccaattt atgtagccaa ggacaatgga   4080

atttatcaga agtgaagtgc ccctctgggc aggagctgag ttcagtgcct ttaaaatgaa   4140

tttccaactc tcatttcttc ccatgatact gaagtacaaa atatccatct aaaatagaaa   4200

ttaaagtcaa gaaggcacac agaaattttc tagtccaagg acttcctttt ataaatgaag   4260

aatcttaggc tcaggtaaag tgacataccc agagtcactc agttgtccca tagagaacca   4320

ggactcaaaa gtcaggtctg cccactctcc ctgaccttgt ttcccctcac cacaccattc   4380

ttccatttat ataatgcatc ctagagattg tgtcaagata tatgactttg tgtcgcgtgg   4440

aaagcaccca gtttatccag caggaggggg atttccactt ttattgcaaa acatgcttgc   4500

ttgatgcaat gcatttcaga tctagaaaaa aataatgcaa gcaagctaca tttacagatg   4560

tgtaaacagg caaaatttcc agaaccgtcc aattttactt ttccaaattt atggaaccaa   4620

cccagatttt ttaaatgaaa atactaaaac catatgtaac cgtaagacaa gctaaaatgt   4680

aagcagacag cctgggaagc actgccctac tgtacaggtg tgatattaag cacaagccat   4740

cctctggcct cttatgagat gttgttattc tctgaaaaac tttgatggaa aaggtttctg   4800

ttaggcttag actgaattag ctaaatgacc atgccacagt attattgtat cactcttctc   4860

acacacctag gcactggttg tggatagttg ccatggtgac aatcaagata atccagatga   4920

cctaaacaaa tgtctgtatg cagctgacac tgctattctc cctcacagtc ttgtcaagag   4980

ccacagtagc tatggcagac atttggttga tggtttcatc atttcctaat acgagagtct   5040

ggcactatgt tggagagagg aatcacttcc tcagagatag gttcctttca actcacatgt   5100

caacagttac tgtacaaaaa gctcagaata cagtaatgat tagagcttga cccctgactt   5160

taggaactta gaaccaaagc ccaaagtccc aggccaaggg cagacattgt gagcagcaga   5220

agggtgtttt ttatggagag ccccataaat ggatgggtgt agaccttgaa gtctgagatg   5280

ggaaatatac cagaatgctc aatgcatcag acatgaagcc ccacgggctt ccatttgaca   5340

tgctggcaat ctgaaggaca aagggcatgg gttatttggg ccttttcccc actccttcaa   5400

tatggctgaa agtgccagtg gggattacaa cctaagaaac cctatgcccc ttcctgaggg   5460

cttgattatt gaatcctgat cttcctggaa tctttcactt gagatgatca cctgcctaac   5520

atccaacatg ttactatgct cttctttatg tacatgagtt actggaaacc aacaataaag   5580

gagagtgagt cat                                                      5593


<210>  6001
<211>  390
<212>  PRT
<213>  Homo sapiens

<400>  6001

Met Cys Val Ser Leu Pro Asp Ala Gly Thr Gly Asp Pro Met Ala Glu 
1               5                   10                  15


Asp Arg Gly Tyr Gly Asn Asp Phe Pro Ile Glu Asp Met Ile Pro Thr 
            20                  25                  30


Leu Lys Ala Ala Ile Arg Ala Val Arg Ile Leu Gln Phe Arg Leu Tyr 
        35                  40                  45


Lys Lys Lys Phe Lys Glu Thr Leu Arg Pro Tyr Asp Val Lys Asp Val 
    50                  55                  60


Ile Glu Gln Tyr Ser Ala Gly His Leu Asp Met Leu Ser Arg Ile Lys 
65                  70                  75                  80


Tyr Leu Gln Thr Arg Ile Asp Met Ile Phe Thr Pro Gly Pro Pro Ser 
                85                  90                  95


Thr Pro Lys His Lys Lys Ser Gln Lys Gly Ser Ala Phe Thr Phe Pro 
            100                 105                 110


Ser Gln Gln Ser Pro Arg Asn Glu Pro Tyr Val Ala Arg Pro Ser Thr 
        115                 120                 125


Ser Glu Ile Glu Asp Gln Ser Met Met Gly Lys Phe Val Lys Val Glu 
    130                 135                 140


Arg Gln Val Gln Asp Met Gly Lys Lys Leu Asp Phe Leu Val Asp Met 
145                 150                 155                 160


His Met Gln His Met Glu Arg Leu Gln Val Gln Val Thr Glu Tyr Tyr 
                165                 170                 175


Pro Thr Lys Gly Thr Ser Ser Pro Ala Glu Ala Glu Lys Lys Glu Asp 
            180                 185                 190


Asn Arg Tyr Ser Asp Leu Lys Thr Ile Ile Cys Asn Tyr Ser Glu Thr 
        195                 200                 205


Gly Pro Pro Glu Pro Pro Tyr Ser Phe His Gln Val Thr Ile Asp Lys 
    210                 215                 220


Val Ser Pro Tyr Gly Phe Phe Ala His Asp Pro Val Asn Leu Pro Arg 
225                 230                 235                 240


Gly Gly Pro Ser Ser Gly Lys Val Gln Ala Thr Pro Pro Ser Ser Ala 
                245                 250                 255


Thr Thr Tyr Val Glu Arg Pro Thr Val Leu Pro Ile Leu Thr Leu Leu 
            260                 265                 270


Asp Ser Arg Val Ser Cys His Ser Gln Ala Asp Leu Gln Gly Pro Tyr 
        275                 280                 285


Ser Asp Arg Ile Ser Pro Arg Gln Arg Arg Ser Ile Thr Arg Asp Ser 
    290                 295                 300


Asp Thr Pro Leu Ser Leu Met Ser Val Asn His Glu Glu Leu Glu Arg 
305                 310                 315                 320


Ser Pro Ser Gly Phe Ser Ile Ser Gln Asp Arg Asp Asp Tyr Val Phe 
                325                 330                 335


Gly Pro Asn Gly Gly Ser Ser Trp Met Arg Glu Lys Arg Tyr Leu Ala 
            340                 345                 350


Glu Gly Glu Thr Asp Thr Asp Thr Asp Pro Phe Thr Pro Ser Gly Ser 
        355                 360                 365


Met Pro Leu Ser Ser Thr Gly Asp Gly Ile Ser Asp Ser Val Trp Thr 
    370                 375                 380


Pro Ser Asn Lys Pro Ile 
385                 390


<210>  6002
<211>  5158
<212>  DNA
<213>  Homo sapiens

<400>  6002
gacccgcgcg ggatgtgacc ccctgacccc ctgcctggcc tcccctgccc cccagggggc     60

ccgcctttgc ctgcttttgg gggggggtgg ggaggggcgc gcggatcatg gcattggagt    120

tcccgggctt gcagccgccg ccgccgcctc gttcacgcac cccgagcgcc ccttcttccc    180

agagcagcag cggagaaggc gaagcggccg gcgggggcga ggcagatggg gctcaaggcg    240

cgcagggcgg cgggggcggc tggcggcggc ggcgacgggg gcggcggagg cggcggggcg    300

gctaacccag ccggagggga cgcggcggcg gccggcgacg aggagcggaa agtggggctg    360

gcgcccggcg acgtggagca agtcaccttg gcgctcgggg ccggagccga caaagacggg    420

accctgctgc tggagggcgg cggccgcgac gaggggcagc ggaggacccc gcagggcatc    480

gggctcctgg ccaagacccc gctgagccgc ccagtcaaga gaaacaacgc caagtaccgg    540

cgcatccaaa ctttgatcta cgacgccctg gagagaccgc ggggctgggc gctgctttac    600

cacgcgttgg tgttcctgat tgtcctgggg tgcttgattc tggctgtcct gaccacattc    660

aaggagtatg agactgtctc gggagactgg cttctgttac tggagacatt tgctattttc    720

atctttggag ccgagtttgc tttgaggatc tgggctgctg gatgttgctg ccgatacaaa    780

ggctggcggg gccgactgaa gtttgccagg aagcccctgt gcatgttgga catctttgtg    840

ctgattgcct ctgtgccagt ggttgctgtg ggaaaccaag gcaatgttct ggccacctcc    900

ctgcgaagcc tgcgcttcct gcagatcctg cgcatgctgc ggatggaccg gagaggtggc    960

acctggaagc ttctgggctc agccatctgt gcccacagca aagaactcat cacggcctgg   1020

tacatcggtt tcctgacact catcctttct tcatttcttg tctacctggt tgagaaagac   1080

gtcccagagg tggatgcaca aggagaggag atgaaagagg agtttgagac ctatgcagat   1140

gccctgtggt ggggcctgat cacactggcc accattggct atggagacaa gacacccaaa   1200

acgtgggaag gccgtctgat tgccgccacc ttttccttaa ttggcgtctc cttttttgcc   1260

cttccagcgg gcatcctggg gtccgggctg gccctcaagg tgcaggagca acaccgtcag   1320

aagcactttg agaaaaggag gaagccagct gctgagctca ttcaggctgc ctggaggtat   1380

tatgctacca accccaacag gattgacctg gtggcgacat ggagatttta tgaatcagtc   1440

gtctcttttc ctttcttcag gcaaaacagc tggaggcagc atccagccaa aagctgggtc   1500

tcttggatcg ggttcgcctt tctaatcctc gtggtagcaa tactaaagga aagctattta   1560

cccctctgaa tgtagatgcc atagaagaaa gtccttctaa agaaccaaag cctgttggct   1620

taaacaataa agagcgtttc cgcacggcct tccgcatgaa agcctacgct ttctggcaga   1680

gttctgaaga tgccgggaca ggtgacccca tggcggaaga caggggctat gggaatgact   1740

tccccatcga agacatgatc cccaccctga aggccgccat ccgagccgtc agaattctac   1800

aattccgtct ctataaaaaa aaattcaagg agactttgag gccttacgat gtgaaggatg   1860

tgattgagca gtattctgcc gggcatctcg acatgctttc caggataaag taccttcaga   1920

cgagaataga tatgattttc acccctggac ctccctccac gccaaaacac aagaagtctc   1980

agaaagggtc agcattcacc ttcccatccc agcaatctcc caggaatgaa ccatatgtag   2040

ccagaccatc cacatcagaa atcgaagacc aaagcatgat ggggaagttt gtaaaagttg   2100

aaagacaggt tcaggacatg gggaagaagc tggacttcct cgtggatatg cacatgcaac   2160

acatggaacg gttgcaggtg caggtcacgg agtattaccc aaccaagggc acctcctcgc   2220

cagctgaagc agagaagaag gaggacaaca ggtattccga tttgaaaacc atcatctgca   2280

actattctga gacaggcccc ccggaaccac cctacagctt ccaccaggtg accattgaca   2340

aagtcagccc ctatgggttt tttgcacatg accctgtgaa cctgccccga gggggaccca   2400

gttctggaaa ggttcaggca actcctcctt cctcagcaac aacgtatgtg gagaggccca   2460

cggtcctgcc tatcttgact cttctcgact cccgagtgag ctgccactcc caggctgacc   2520

tgcagggccc ctactcggac cgaatctccc cccggcagag acgtagcatc acgcgagaca   2580

gtgacacacc tctgtccctg atgtcggtca accacgagga gctggagagg tctccaagtg   2640

gcttcagcat ctcccaggac agagatgatt atgtgttcgg ccccaatggg gggtcgagct   2700

ggatgaggga gaagcggtac ctcgccgagg gtgagacgga cacagacacg gaccccttca   2760

cgcccagcgg ctccatgcct ctgtcgtcca caggggatgg gatttctgat tcagtatgga   2820

ccccttccaa taagcccatt taaaagaggt cactggctga cccctccttg taatgtagac   2880

agactttgta tagttcactt actcttacac ccgacgctta ccagcgggga caccaatggc   2940

tgcatcaaat gcatgcgtgt gcgtggtggc cccacccagg caggggcttc ccacagcctc   3000

ttcctcccca tgtcaccaca acaaagtgct tccttttcag catggtttgc atgactttac   3060

actatataaa tggttccgct aatctcttct aggatacaca tttatctgct gttcttactt   3120

ttaatcacga ttggaccagt acagggagaa attactgatg agccatgcta tttgtctgtt   3180

tggttggctg gtttgggttt tggtttggta agcagagaaa gtagtttaag ttatttctag   3240

gatcactgcc ctcttgtgta aaacgctcca gcaattaact gtttttgaaa gcaaggaaat   3300

aattttctca acaaaaccac attgtgtatc agtggggctg cctactgagc taacattagg   3360

aaaggaatga gatagtcatt gtgtctctaa aacaaagaat ttaaacaaat atttaaggca   3420

aaacctttta aaagctctcc aaaagacctc acttggcctg atgttactta gtatcatgcc   3480

tcagtttcct tatctgtaaa aagtggtggt aatcccaagt gtagcatttc tgatgagtta   3540

tgaattggca gggagaaaac acacacacac acacacacac acacacacac acacacatac   3600

acaaagttaa aatagtttcc aatttatgta gccaaggaca atggaattta tcagaagtga   3660

agtgcccctc tgggcaggag ctgagttcag tgcctttaaa atgaatttcc aactctcatt   3720

tcttcccatg atactgaagt acaaaatatc catctaaaat agaaattaaa gtcaagaagg   3780

cacacagaaa ttttctagtc caaggacttc cttttataaa tgaagaatct taggctcagg   3840

taaagtgaca tacccagagt cactcagttg tcccatagag aaccaggact caaaagtcag   3900

gtctgcccac tctccctgac cttgtttccc ctcaccacac cattcttcca tttatataat   3960

gcatcctaga gattgtgtca agatatatga ctttgtgtcg cgtggaaagc acccagttta   4020

tccagcagga gggggatttc cacttttatt gcaaaacatg cttgcttgat gcaatgcatt   4080

tcagatctag aaaaaaataa tgcaagcaag ctacatttac agatgtgtaa acaggcaaaa   4140

tttccagaac cgtccaattt tacttttcca aatttatgga accaacccag attttttaaa   4200

tgaaaatact aaaaccatat gtaaccgtaa gacaagctaa aatgtaagca gacagcctgg   4260

gaagcactgc cctactgtac aggtgtgata ttaagcacaa gccatcctct ggcctcttat   4320

gagatgttgt tattctctga aaaactttga tggaaaaggt ttctgttagg cttagactga   4380

attagctaaa tgaccatgcc acagtattat tgtatcactc ttctcacaca cctaggcact   4440

ggttgtggat agttgccatg gtgacaatca agataatcca gatgacctaa acaaatgtct   4500

gtatgcagct gacactgcta ttctccctca cagtcttgtc aagagccaca gtagctatgg   4560

cagacatttg gttgatggtt tcatcatttc ctaatacgag agtctggcac tatgttggag   4620

agaggaatca cttcctcaga gataggttcc tttcaactca catgtcaaca gttactgtac   4680

aaaaagctca gaatacagta atgattagag cttgacccct gactttagga acttagaacc   4740

aaagcccaaa gtcccaggcc aagggcagac attgtgagca gcagaagggt gttttttatg   4800

gagagcccca taaatggatg ggtgtagacc ttgaagtctg agatgggaaa tataccagaa   4860

tgctcaatgc atcagacatg aagccccacg ggcttccatt tgacatgctg gcaatctgaa   4920

ggacaaaggg catgggttat ttgggccttt tccccactcc ttcaatatgg ctgaaagtgc   4980

cagtggggat tacaacctaa gaaaccctat gccccttcct gagggcttga ttattgaatc   5040

ctgatcttcc tggaatcttt cacttgagat gatcacctgc ctaacatcca acatgttact   5100

atgctcttct ttatgtacat gagttactgg aaaccaacaa taaaggagag tgagtcat     5158


<210>  6003
<211>  447
<212>  PRT
<213>  Homo sapiens

<400>  6003

Met Gly Leu Lys Ala Arg Arg Ala Ala Gly Ala Ala Gly Gly Gly Gly 
1               5                   10                  15


Asp Gly Gly Gly Gly Gly Gly Gly Ala Ala Asn Pro Ala Gly Gly Asp 
            20                  25                  30


Ala Ala Ala Ala Gly Asp Glu Glu Arg Lys Val Gly Leu Ala Pro Gly 
        35                  40                  45


Asp Val Glu Gln Val Thr Leu Ala Leu Gly Ala Gly Ala Asp Lys Asp 
    50                  55                  60


Gly Thr Leu Leu Leu Glu Gly Gly Gly Arg Asp Glu Gly Gln Arg Arg 
65                  70                  75                  80


Thr Pro Gln Gly Ile Gly Leu Leu Ala Lys Thr Pro Leu Ser Arg Pro 
                85                  90                  95


Val Lys Arg Asn Asn Ala Lys Tyr Arg Arg Ile Gln Thr Leu Ile Tyr 
            100                 105                 110


Asp Ala Leu Glu Arg Pro Arg Gly Trp Ala Leu Leu Tyr His Ala Leu 
        115                 120                 125


Val Phe Leu Ile Val Leu Gly Cys Leu Ile Leu Ala Val Leu Thr Thr 
    130                 135                 140


Phe Lys Glu Tyr Glu Thr Val Ser Gly Asp Trp Leu Leu Leu Leu Glu 
145                 150                 155                 160


Thr Phe Ala Ile Phe Ile Phe Gly Ala Glu Phe Ala Leu Arg Ile Trp 
                165                 170                 175


Ala Ala Gly Cys Cys Cys Arg Tyr Lys Gly Trp Arg Gly Arg Leu Lys 
            180                 185                 190


Phe Ala Arg Lys Pro Leu Cys Met Leu Asp Ile Phe Val Leu Ile Ala 
        195                 200                 205


Ser Val Pro Val Val Ala Val Gly Asn Gln Gly Asn Val Leu Ala Thr 
    210                 215                 220


Ser Leu Arg Ser Leu Arg Phe Leu Gln Ile Leu Arg Met Leu Arg Met 
225                 230                 235                 240


Asp Arg Arg Gly Gly Thr Trp Lys Leu Leu Gly Ser Ala Ile Cys Ala 
                245                 250                 255


His Ser Lys Glu Leu Ile Thr Ala Trp Tyr Ile Gly Phe Leu Thr Leu 
            260                 265                 270


Ile Leu Ser Ser Phe Leu Val Tyr Leu Val Glu Lys Asp Val Pro Glu 
        275                 280                 285


Val Asp Ala Gln Gly Glu Glu Met Lys Glu Glu Phe Glu Thr Tyr Ala 
    290                 295                 300


Asp Ala Leu Trp Trp Gly Leu Ile Thr Leu Ala Thr Ile Gly Tyr Gly 
305                 310                 315                 320


Asp Lys Thr Pro Lys Thr Trp Glu Gly Arg Leu Ile Ala Ala Thr Phe 
                325                 330                 335


Ser Leu Ile Gly Val Ser Phe Phe Ala Leu Pro Ala Gly Ile Leu Gly 
            340                 345                 350


Ser Gly Leu Ala Leu Lys Val Gln Glu Gln His Arg Gln Lys His Phe 
        355                 360                 365


Glu Lys Arg Arg Lys Pro Ala Ala Glu Leu Ile Gln Ala Ala Trp Arg 
    370                 375                 380


Tyr Tyr Ala Thr Asn Pro Asn Arg Ile Asp Leu Val Ala Thr Trp Arg 
385                 390                 395                 400


Phe Tyr Glu Ser Val Val Ser Phe Pro Phe Phe Arg Gln Asn Ser Trp 
                405                 410                 415


Arg Gln His Pro Ala Lys Ser Trp Val Ser Trp Ile Gly Phe Ala Phe 
            420                 425                 430


Leu Ile Leu Val Val Ala Ile Leu Lys Glu Ser Tyr Leu Pro Leu 
        435                 440                 445


<210>  6004
<211>  3530
<212>  DNA
<213>  Homo sapiens

<400>  6004
cggccgcgac gaggggcagc ggaggacccc gcagggcatc gggctcctgg ccaagacccc     60

gctgagccgc ccagtcaaga gaaacaacgc caagtaccgg cgcatccaaa ctttgatcta    120

cgacgccctg gagagaccgc ggggctgggc gctgctttac cacgcgttgg tgttcctgat    180

tgtcctgggg tgcttgattc tggctgtcct gaccacattc aaggagtatg agactgtctc    240

gggagactgg cttctgttac tggagacatt tgctattttc atctttggag ccgagtttgc    300

tttgaggatc tgggctgctg gatgttgctg ccgatacaaa ggctggcggg gccgactgaa    360

gtttgccagg aagcccctgt gcatgttgga catctttgtg ctgattgcct ctgtgccagt    420

ggttgctgtg ggaaaccaag gcaatgttct ggccacctcc ctgcgaagcc tgcgcttcct    480

gcagatcctg cgcatgctgc ggatggaccg gagaggtggc acctggaagc ttctgggctc    540

agccatctgt gcccacagca aagaactcat cacggcctgg tacatcggtt tcctgacact    600

catcctttct tcatttcttg tctacctggt tgagaaagac gtcccagagg tggatgcaca    660

aggagaggag atgaaagagg agtttgagac ctatgcagat gccctgtggt ggggcctgat    720

cacactggcc accattggct atggagacaa gacacccaaa acgtgggaag gccgtctgat    780

tgccgccacc ttttccttaa ttggcgtctc cttttttgcc cttccagcgg gcatcctggg    840

gtccgggctg gccctcaagg tgcaggagca acaccgtcag aagcactttg agaaaaggag    900

gaagccagct gctgagctca ttcaggctgc ctggaggtat tatgctacca accccaacag    960

gattgacctg gtggcgacat ggagatttta tgaatcagtc gtctcttttc ctttcttcag   1020

gcaaaacagc tggaggcagc atccagccaa aagctgggtc tcttggatcg ggttcgcctt   1080

tctaatcctc gtggtagcaa tactaaagga aagctattta cccctctgaa tgtagatgcc   1140

atagaagaaa gtccttctaa agaaccaaag cctgttggct taaacaataa agagcgtttc   1200

cgcacggcct tccgcatgaa agcctacgct ttctggcaga gttctgaagg taatgccttt   1260

ttatctccct ccctgtctct tccacttctt cctcccccaa gtccacttcc ttcctcacct   1320

ctccctttgc ccacttaaga acctttgact ccacaaggta actctctccc ttccctcgac   1380

aagccaactt cttgcttccc taactcctcc tgtcccttgg gctgaggcat tgtgatgtat   1440

tcccaggagt ctagggctgc aggctcccaa gttaggagcc tggaaacctg tcaccttggt   1500

ttctaagggt ccgccccgac cccccgcccc atgattggat tgttatggag gtcaacttga   1560

aggatggggc ggtgccaggt gcaaagcaat ttagagacca gggcacggga agagtggcag   1620

aaaagcgccc tctggaggct gtaggagcca tggcctcatg tgcctctttt acttatgcaa   1680

agggaggaca tgcagaaaag cctgtttcct cagtgtctga gcccacccag gccctcaatc   1740

ctcattgtat cattcagttc tctccaaggc ctctgatgtg acagtgtgtg ttgtttgctg   1800

gcttctgtgt cctttgctgg cttctggctc tgggggccac tctggaactg cggagctcac   1860

ttctcctccc tgctagcctt ttccctcact accagtcatg agctgcgcac acttttgact   1920

tggacttctg ggtaatagaa tgagggtgcc aagaaaggct gaacagcatc acagcttgag   1980

aataccgtgg agtcttgcaa cgtggaaata aagactctgg ggattgacac atccagaggc   2040

gtggaaggct ttgaccgaac agtggggtcc ccaagccttt tccaggtctg tggcctgccg   2100

ttcatatgtg tgtctccctc ccagatgccg ggacaggtga ccccatggcg gaagacaggg   2160

gctatgggaa tgacttcccc atcgaagaca tgatccccac cctgaaggcc gccatccgag   2220

ccgtcagaat tctacaattc cgtctctata aaaaaaaatt caaggagact ttgaggcctt   2280

acgatgtgaa ggatgtgatt gagcagtatt ctgccgggca tctcgacatg ctttccagga   2340

taaagtacct tcagacgaga atagatatga ttttcacccc tggacctccc tccacgccaa   2400

aacacaagaa gtctcagaaa gggtcagcat tcaccttccc atcccagcaa tctcccagga   2460

atgaaccata tgtagccaga ccatccacat cagaaatcga agaccaaagc atgatgggga   2520

agtttgtaaa agttgaaaga caggttcagg acatggggaa gaagctggac ttcctcgtgg   2580

atatgcacat gcaacacatg gaacggttgc aggtgcaggt cacggagtat tacccaacca   2640

agggcacctc ctcgccagct gaagcagaga agaaggagga caacaggtat tccgatttga   2700

aaaccatcat ctgcaactat tctgagacag gccccccgga accaccctac agcttccacc   2760

aggtgaccat tgacaaagtc agcccctatg ggttttttgc acatgaccct gtgaacctgc   2820

cccgaggggg acccagttct ggaaaggttc aggcaactcc tccttcctca gcaacaacgt   2880

atgtggagag gcccacggtc ctgcctatct tgactcttct cgactcccga gtgagctgcc   2940

actcccaggc tgacctgcag ggcccctact cggaccgaat ctccccccgg cagagacgta   3000

gcatcacgcg agacagtgac acacctctgt ccctgatgtc ggtcaaccac gaggagctgg   3060

agaggtctcc aagtggcttc agcatctccc aggacagaga tgattatgtg ttcggcccca   3120

atggggggtc gagctggatg agggagaagc ggtacctcgc cgagggtgag acggacacag   3180

acacggaccc cttcacgccc agcggctcca tgcctctgtc gtccacaggg gatgggattt   3240

ctgattcagt atggacccct tccaataagc ccatttaaaa gaggtcactg gctgacccct   3300

ccttgtaatg tagacagact ttgtatagtt cacttactct tacacccgac gcttaccagc   3360

ggggacacca atggctgcat caaatgcatg cgtgtgcgtg gtggccccac ccaggcaggg   3420

gcttcccaca gcctcttcct ccccatgtca ccacaacaaa gtgcttcctt ttcagcatgg   3480

tttgcatgac tttacactat ataaatggtt ccgctaatct cttctaggat              3530


<210>  6005
<211>  390
<212>  PRT
<213>  Homo sapiens

<400>  6005

Met Cys Val Ser Leu Pro Asp Ala Gly Thr Gly Asp Pro Met Ala Glu 
1               5                   10                  15


Asp Arg Gly Tyr Gly Asn Asp Phe Pro Ile Glu Asp Met Ile Pro Thr 
            20                  25                  30


Leu Lys Ala Ala Ile Arg Ala Val Arg Ile Leu Gln Phe Arg Leu Tyr 
        35                  40                  45


Lys Lys Lys Phe Lys Glu Thr Leu Arg Pro Tyr Asp Val Lys Asp Val 
    50                  55                  60


Ile Glu Gln Tyr Ser Ala Gly His Leu Asp Met Leu Ser Arg Ile Lys 
65                  70                  75                  80


Tyr Leu Gln Thr Arg Ile Asp Met Ile Phe Thr Pro Gly Pro Pro Ser 
                85                  90                  95


Thr Pro Lys His Lys Lys Ser Gln Lys Gly Ser Ala Phe Thr Phe Pro 
            100                 105                 110


Ser Gln Gln Ser Pro Arg Asn Glu Pro Tyr Val Ala Arg Pro Ser Thr 
        115                 120                 125


Ser Glu Ile Glu Asp Gln Ser Met Met Gly Lys Phe Val Lys Val Glu 
    130                 135                 140


Arg Gln Val Gln Asp Met Gly Lys Lys Leu Asp Phe Leu Val Asp Met 
145                 150                 155                 160


His Met Gln His Met Glu Arg Leu Gln Val Gln Val Thr Glu Tyr Tyr 
                165                 170                 175


Pro Thr Lys Gly Thr Ser Ser Pro Ala Glu Ala Glu Lys Lys Glu Asp 
            180                 185                 190


Asn Arg Tyr Ser Asp Leu Lys Thr Ile Ile Cys Asn Tyr Ser Glu Thr 
        195                 200                 205


Gly Pro Pro Glu Pro Pro Tyr Ser Phe His Gln Val Thr Ile Asp Lys 
    210                 215                 220


Val Ser Pro Tyr Gly Phe Phe Ala His Asp Pro Val Asn Leu Pro Arg 
225                 230                 235                 240


Gly Gly Pro Ser Ser Gly Lys Val Gln Ala Thr Pro Pro Ser Ser Ala 
                245                 250                 255


Thr Thr Tyr Val Glu Arg Pro Thr Val Leu Pro Ile Leu Thr Leu Leu 
            260                 265                 270


Asp Ser Arg Val Ser Cys His Ser Gln Ala Asp Leu Gln Gly Pro Tyr 
        275                 280                 285


Ser Asp Arg Ile Ser Pro Arg Gln Arg Arg Ser Ile Thr Arg Asp Ser 
    290                 295                 300


Asp Thr Pro Leu Ser Leu Met Ser Val Asn His Glu Glu Leu Glu Arg 
305                 310                 315                 320


Ser Pro Ser Gly Phe Ser Ile Ser Gln Asp Arg Asp Asp Tyr Val Phe 
                325                 330                 335


Gly Pro Asn Gly Gly Ser Ser Trp Met Arg Glu Lys Arg Tyr Leu Ala 
            340                 345                 350


Glu Gly Glu Thr Asp Thr Asp Thr Asp Pro Phe Thr Pro Ser Gly Ser 
        355                 360                 365


Met Pro Leu Ser Ser Thr Gly Asp Gly Ile Ser Asp Ser Val Trp Thr 
    370                 375                 380


Pro Ser Asn Lys Pro Ile 
385                 390


<210>  6006
<211>  2729
<212>  DNA
<213>  Homo sapiens

<400>  6006
ggcgacgtgg agcaagtcac cttggcgctc ggggccggag ccgacaaaga cgggaccctg     60

ctgctggagg gcggcggccg cgacgagggg cagcggagga ccccgcaggg catcgggctc    120

ctggccaaga ccccgctgag ccgcccagtc aagagaaaca acgccaagta ccggcgcatc    180

caaactttga tctacgacgc cctggagaga ccgcggggct gggcgctgct ttaccacgcg    240

ttggtgttcc tgattgtcct ggggtgcttg attctggctg tcctgaccac attcaaggag    300

tatgagactg tctcgggaga ctggcttctg ttactggaga catttgctat tttcatcttt    360

ggagccgagt ttgctttgag gatctgggct gctggatgtt gctgccgata caaaggctgg    420

cggggccgac tgaagtttgc caggaagccc ctgtgcatgt tggacatctt tgtgctgatt    480

gcctctgtgc cagtggttgc tgtgggaaac caaggcaatg ttctggccac ctccctgcga    540

agcctgcgct tcctgcagat cctgcgcatg ctgcggatgg accggagagg tggcacctgg    600

aagcttctgg gctcagccat ctgtgcccac agcaaagaac tcatcacggc ctggtacatc    660

ggtttcctga cactcatcct ttcttcattt cttgtctacc tggttgagaa agacgtccca    720

gaggtggatg cacaaggaga ggagatgaaa gaggagtttg agacctatgc agatgccctg    780

tggtggggcc tgatcacact ggccaccatt ggctatggag acaagacacc caaaacgtgg    840

gaaggccgtc tgattgccgc caccttttcc ttaattggcg tctccttttt tgcccttcca    900

gcgggcatcc tggggtccgg gctggccctc aaggtgcagg agcaacaccg tcagaagcac    960

tttgagaaaa ggaggaagcc agctgctgag ctcattcagg ctgcctggag gtattatgct   1020

accaacccca acaggattga cctggtggcg acatggagat tttatgaatc agtcgtctct   1080

tttcctttct tcaggcaaaa cagctggagg cagcatccag ccaaaagctg ggtctcttgg   1140

atcgggttcg cctttctaat cctcgtggta gcaatactaa aggaaagcta tttacccctc   1200

tgaatgtaga tgccatagaa gaaagtcctt ctaaagaacc aaagcctgtt ggcttaaaca   1260

ataaagagcg tttccgcacg gccttccgca tgaaagccta cgctttctgg cagagttctg   1320

aagatgccgg gacaggtgac cccatggcgg aagacagggg ctatgggaat gacttcccca   1380

tcgaagacat gatccccacc ctgaaggccg ccatccgagc cgtcagaatt ctacaattcc   1440

gtctctataa aaaaaaattc aaggagactt tgaggcctta cgatgtgaag gatgtgattg   1500

agcagtattc tgccgggcat ctcgacatgc tttccaggat aaagtacctt cagacgagaa   1560

tagatatgat tttcacccct ggacctccct ccacgccaaa acacaagaag tctcagaaag   1620

ggtcagcatt caccttccca tcccagcaat ctcccaggaa tgaaccatat gtagccagac   1680

catccacatc agaaatcgaa gaccaaagca tgatggggaa gtttgtaaaa gttgaaagac   1740

aggttcagga catggggaag aagctggact tcctcgtgga tatgcacatg caacacatgg   1800

aacggttgca ggtgcaggtc acggagtatt acccaaccaa gggcacctcc tcgccagctg   1860

aagcagagaa gaaggaggac aacaggtatt ccgatttgaa aaccatcatc tgcaactatt   1920

ctgagacagg ccccccggaa ccaccctaca gcttccacca ggtgaccatt gacaaagtca   1980

gcccctatgg gttttttgca catgaccctg tgaacctgcc ccgaggggga cccagttctg   2040

gaaaggttca ggcaactcct ccttcctcag caacaacgta tgtggagagg cccacggtcc   2100

tgcctatctt gactcttctc gactcccgag tgagctgcca ctcccaggct gacctgcagg   2160

gcccctactc ggaccgaatc tccccccggc agagacgtag catcacgcga gacagtgaca   2220

cacctctgtc cctgatgtcg gtcaaccacg aggagctgga gaggtctcca agtggcttca   2280

gcatctccca ggacagagat gattatgtgt tcggccccaa tggggggtcg agctggatga   2340

gggagaagcg gtacctcgcc gagggtgaga cggacacaga cacggacccc ttcacgccca   2400

gcggctccat gcctctgtcg tccacagggg atgggatttc tgattcagta tggacccctt   2460

ccaataagcc catttaaaag aggtcactgg ctgacccctc cttgtaatgt agacagactt   2520

tgtatagttc acttactctt acacccgacg cttaccagcg gggacaccaa tggctgcatc   2580

aaatgcatgc gtgtgcgtgg tggccccacc caggcagggg cttcccacag cctcttcctc   2640

cccatgtcac cacaacaaag tgcttccttt tcagcatggt ttgcatgact ttacactata   2700

taaatggttc cgctaatctc ttctaggat                                     2729


<210>  6007
<211>  395
<212>  PRT
<213>  Homo sapiens

<400>  6007

Met Lys Ala Tyr Ala Phe Trp Gln Ser Ser Glu Asp Ala Gly Thr Gly 
1               5                   10                  15


Asp Pro Met Ala Glu Asp Arg Gly Tyr Gly Asn Asp Phe Pro Ile Glu 
            20                  25                  30


Asp Met Ile Pro Thr Leu Lys Ala Ala Ile Arg Ala Val Arg Ile Leu 
        35                  40                  45


Gln Phe Arg Leu Tyr Lys Lys Lys Phe Lys Glu Thr Leu Arg Pro Tyr 
    50                  55                  60


Asp Val Lys Asp Val Ile Glu Gln Tyr Ser Ala Gly His Leu Asp Met 
65                  70                  75                  80


Leu Ser Arg Ile Lys Tyr Leu Gln Thr Arg Ile Asp Met Ile Phe Thr 
                85                  90                  95


Pro Gly Pro Pro Ser Thr Pro Lys His Lys Lys Ser Gln Lys Gly Ser 
            100                 105                 110


Ala Phe Thr Phe Pro Ser Gln Gln Ser Pro Arg Asn Glu Pro Tyr Val 
        115                 120                 125


Ala Arg Pro Ser Thr Ser Glu Ile Glu Asp Gln Ser Met Met Gly Lys 
    130                 135                 140


Phe Val Lys Val Glu Arg Gln Val Gln Asp Met Gly Lys Lys Leu Asp 
145                 150                 155                 160


Phe Leu Val Asp Met His Met Gln His Met Glu Arg Leu Gln Val Gln 
                165                 170                 175


Val Thr Glu Tyr Tyr Pro Thr Lys Gly Thr Ser Ser Pro Ala Glu Ala 
            180                 185                 190


Glu Lys Lys Glu Asp Asn Arg Tyr Ser Asp Leu Lys Thr Ile Ile Cys 
        195                 200                 205


Asn Tyr Ser Glu Thr Gly Pro Pro Glu Pro Pro Tyr Ser Phe His Gln 
    210                 215                 220


Val Thr Ile Asp Lys Val Ser Pro Tyr Gly Phe Phe Ala His Asp Pro 
225                 230                 235                 240


Val Asn Leu Pro Arg Gly Gly Pro Ser Ser Gly Lys Val Gln Ala Thr 
                245                 250                 255


Pro Pro Ser Ser Ala Thr Thr Tyr Val Glu Arg Pro Thr Val Leu Pro 
            260                 265                 270


Ile Leu Thr Leu Leu Asp Ser Arg Val Ser Cys His Ser Gln Ala Asp 
        275                 280                 285


Leu Gln Gly Pro Tyr Ser Asp Arg Ile Ser Pro Arg Gln Arg Arg Ser 
    290                 295                 300


Ile Thr Arg Asp Ser Asp Thr Pro Leu Ser Leu Met Ser Val Asn His 
305                 310                 315                 320


Glu Glu Leu Glu Arg Ser Pro Ser Gly Phe Ser Ile Ser Gln Asp Arg 
                325                 330                 335


Asp Asp Tyr Val Phe Gly Pro Asn Gly Gly Ser Ser Trp Met Arg Glu 
            340                 345                 350


Lys Arg Tyr Leu Ala Glu Gly Glu Thr Asp Thr Asp Thr Asp Pro Phe 
        355                 360                 365


Thr Pro Ser Gly Ser Met Pro Leu Ser Ser Thr Gly Asp Gly Ile Ser 
    370                 375                 380


Asp Ser Val Trp Thr Pro Ser Asn Lys Pro Ile 
385                 390                 395


<210>  6008
<211>  9367
<212>  DNA
<213>  Homo sapiens

<400>  6008
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aaagccgtca gctcctcctc   2100

aagacattag ttgcaccagc ccaagttcca ctagtatttt ggtaagttgg caacctccac   2160

cagtggaaaa acagaatggc attatcactg aatactccat caagtacact gcagtggatg   2220

gggaagatga caagcctcac gagattttgg gaattccttc ggacactacc aaataccttt   2280

tggaacagct ggaaaaatgg actgaatacc ggatcactgt gacagcccat acagatgtcg   2340

gccctggccc tgagagcttg tccgtgttga ttcgaaccaa tgaagatgtt cctagtggtc   2400

ctcctcgcaa agtcgaggta gaggctgtca actcaacatc tgttaaagtc tcatggcgct   2460

cacccgtgcc caataaacag catggccaga taagaggata tcaggtgcat tatgtgagga   2520

tggaaaatgg tgagcccaag ggccagccca tgctgaaaga tgtcatgctg gctgatgcac   2580

aggacatgat catttctggg ctccagcctg aaacttccta ctccctcacc gtcacagcct   2640

acacaaccaa aggagatggt gctcgcagca agcccaaact ggtgtccacc actggggcag   2700

ttccagggaa acctcggctt gtgattaacc acactcagat gaatactgct cttattcagt   2760

ggcaccctcc ggtggacaca tttggacctc ttcagggcta ccgtctaaaa tttggccgca   2820

aggatatgga gccacttact actcttgagt tctctgaaaa agaagatcac tttacagcta   2880

cagacatcca caagggagca tcatacgtct tcaggctctc agccagaaac aaagtgggct   2940

ttggggagga gatggtgaag gagatttcca ttccagaaga agtaccaact ggattccctc   3000

aaaaccttca ctcagaaggc accacttcaa cctccgtcca gttatcttgg caaccacctg   3060

tcctggcaga gagaaatggc attatcacca agtataccct tctttatagg gatatcaaca   3120

tcccccttct cccgatggag cagcttattg ttccagctga caccactatg acactcactg   3180

gcttaaaacc agataccaca tacgatgtaa aagtacgtgc tcatacgagc aaagggcccg   3240

ggccatatag tcccagtgtc cagttcagga cactgcctgt ggatcaagtg tttgcaaaaa   3300

attttcatgt caaagcagta atgaagactt ccgtgttgct gtcttgggag attccagaga   3360

attataactc cgccatgcct ttcaaaattc tttatgatga tgggaaaatg gtagaagaag   3420

tggatggccg agccacacag aagttaattg tcaacctgaa gcctgagaaa tcatattcat   3480

ttgtgctgac aaatcgtgga aacagtgctg gtgggctgca gcacagggtc acggcaaaga   3540

ctgcaccaga tgtattacgt accaagcctg ccttcattgg gaagaccaac ttggatggca   3600

tgattactgt gcaactgcct gaagtacctg caaatgagaa tataaaaggt tactacataa   3660

taattgtgcc tttgaagaaa tctcgcggga aatttatcaa gccatgggag agtccagatg   3720

aaatggaatt agatgagctg cttaaggaga tatctaggaa gcgcagaagc atccgttatg   3780

ggagagaagt tgaattaaag ccatatattg ccgctcactt tgatgtcctt cccactgagt   3840

tcaccctggg ggatgacaag cattatggtg gatttacaaa caagcaactc caaagtggtc   3900

aagaatatgt cttctttgtg ttagcagtaa tggaacatgc agagtctaag atgtatgcaa   3960

ccagccctta ctccgacccc gtggtgtcaa tggatctgga tccgcagcca atcacggatg   4020

aagaagaagg cttgatctgg gttgtaggtc ctgtccttgc agtggtcttt atcatctgca   4080

ttgtcattgc tattcttctt tataaaagga agagggcaga gtccgactct agaaaaagca   4140

gcataccgaa caataaggag atcccttcac accacccaac agaccctgta gaactgaggc   4200

gccttaactt tcaaacaccg ggtatggcta gccatcctcc aatacccatc ttggaacttg   4260

cagaccacat tgaaagattg aaagcaaatg acaacttgaa gttttcccag gaatatgagt   4320

caattgaccc tggccagcag ttcacttggg aacattcaaa cttggaagta aacaaaccaa   4380

agaatagata cgcgaatgta atcgcatatg atcattcccg ggttctccta tcagctatag   4440

aagggatccc aggaagtgac tatgtgaatg ccaactacat agatgggtat aggaagcaaa   4500

atgcctatat tgcaacacag ggatctctcc ccgaaacatt tggggacttt tggagaatga   4560

tatgggaaca acggagtgcc acagttgtca tgatgacaaa actagaagaa agatcaaggg   4620

tgaagtgtga ccagtattgg cctagcagag gcacagaaac ccacggactc gttcaagtaa   4680

cgctgcttga tactgtggag ctggccacat attgtgttcg aacatttgca ctttacaaga   4740

atggttcaag tgagaagaga gaagtgagac aattccagtt caccgcctgg cctgatcatg   4800

gtgttccaga acaccctaca ccttttctag ctttcttacg tagagtcaaa acctgtaacc   4860

ctcccgatgc tggtccgatg gttgtgcact gcagtgcggg agttggccgg actggttgct   4920

tcatcgtcat agatgccatg ttagaaagaa taaagcatga aaaaactgta gatatttatg   4980

gccatgtaac tttaatgaga gcccagagga actatatggt tcaaacagaa gaccaataca   5040

tctttatcca tgatgcactg ttagaagcag tgacttgtgg aaataccgaa gtgccagcta   5100

gaaacttgta tgcctacatt cagaagctga cacaaataga aacgggagag aatgtcacag   5160

gaatggagct cgaatttaag cgtctagcca gctcaaaagc tcacacctca aggtttatca   5220

gtgccaatct tccatgtaat aaattcaaaa atcgccttgt taatattatg ccatatgaat   5280

ccacaagggt atgcctgcag cctatccgtg gagtagaagg atctgattac atcaatgcca   5340

gttttattga tggatacaga caacagaaag cctacatcgc tacccagggg cccttggcag   5400

agaccactga agacttctgg cggatgctct gggaacacaa ttccaccata gttgtgatgc   5460

tcaccaagct gcgtgaaatg ggcagagaga aatgtcacca atactggcca gcagaacggt   5520

ctgcaagata ccagtacttt gttgtagatc ccatggctga gtacaacatg ccacagtata   5580

tcctaaggga attcaaggtc acagatgcca gggacggcca gtcccgaaca gtaaggcagt   5640

tccagttcac tgactggcca gagcaaggag tgccaaagtc cggagaagga tttattgact   5700

tcatcggcca agtccataaa acaaaagaac agtttggcca agatggaccc atttcagtcc   5760

attgcagcgc gggcgttgga agaactggag tcttcataac gctaagcatt gttttggaaa   5820

gaatgagata tgaaggagtt gtagatatct tccagactgt caaaatgtta agaacacaac   5880

gaccagctat ggtacagaca gaggatcaat atcagttttc ctatcgtgcc gcactagagt   5940

acctgggcag ctttgaccac tatgcaacgt agaaacccct gacccattct ggatttttac   6000

tacaggccct tcaatatcca tggagtctct tctgagccat acagggcact tgagaagtcc   6060

ttcttaactt ctagctaaca actacttagt gggactatta cacacaaaac aaattaaaaa   6120

caaattattc caggtggacc aagaatctgc tttgacatcg ccccttccca ccatactgct   6180

cataataaca ttttaggggg aaaggggagg gaatgtttaa aaagaaagtc cttgatttag   6240

ttttttagta ttgtaaagat actgctgacc tgtgcttcat ttctaactgt gtaaactttt   6300

ttttaacaaa atgtatcatt cgataaagtg aattttaaaa aagttacata actcttcatt   6360

tttttatttc caaatcgtag gtttttttaa gctgtagaac tgttatctgt aatatcttgc   6420

tgtagaaata tcaaatcatt tgaaaatttg cacatttttg tgcaaaactc aatctacagt   6480

atcagtctcg tcagatatat taattttaca cttcagtttt gattggtgag aaagtaccca   6540

ttctcttcaa ataatcaaag ataattatta ttttgttttg tttttggaat caacagggag   6600

gcgcaaagta taaagttgct gctaacatat atacatatat atccatattt tataagggtg   6660

tctatgtata tatagacagt gtgtccacac aaaaaataga tacagttatc agtcagtcag   6720

ttcttccatg atttagtttt tttaaacgta gaaaagctat tgtaaacatc tctttccatt   6780

tattcttaat tttttgacat attggtattt ctttaaaggg aaatgaggaa tgcacatcag   6840

tgattgattg tcaaacctca ccccctgatt tcctacctaa tctaccccca cctaaccaat   6900

caatcacatc cacaaattgt tttgtttgtt tgttagtcag gcttccaaca aagttcaata   6960

tttctaacac tctagtgcaa taaaaattat tattaaatag ctaagaggtg tgcatgtggg   7020

aaaggtcagt gcatatccct ttaggagggg agaatgttgt aatatatcag ctatcgagtt   7080

gtttaaaaaa agtgtattca atcgtatatt gtctatagta tgtgctatga aatttgcatt   7140

tatgatatgt aacaggggca aagccaaatt catgttactc tgttcagtca gaaacatttt   7200

gtggcataca gcattcctgg gaagtgctgt actttgtttc gttttggttt tagttttgca   7260

tttagagtgc cttataattg atgcctattt taatagcatt tctttttagc ttttggttcg   7320

tatttccatt cactgttcgt atctgttact ttctattaaa gcattatctg tttaccacat   7380

gtacaaaaac tctttgaata atatgcattc ctagttttca gccaagtcgg ggatgttagt   7440

gattgtacca gcccaaagca cttggataat cagggccctt cttcctttta taatcaatca   7500

tcaacatcag aaaaagctac ttgttttatt tatattccct tccaaatccg ctctggaaca   7560

tgcagtaact gcaccaaact tattttagta acaaatatca ttggcaactt tggaatatat   7620

ttgatattcc attaggattt ttctaaaagg ggaaataaac tatatatata tatgtatctt   7680

acccccaatt cttccaacag aatttctata ggaagccatg gatgatggca taagtttgcc   7740

acatattaca tgattttaaa taatcctcaa aatacccaag gaactcttaa agagttttgg   7800

tatgagtata ctactttggt ttaattttag cttcatggat gttctgcatg gaaggatttt   7860

tgttttccac attttcccat tgctagcaga gtgaaatcca agagaccaaa catttgcaag   7920

cattgtattt gagcactttt gtaaaaaaca aagaaaaaga aaaaaaagaa aatatatata   7980

atactaaaaa aaagtatcta gaaggctacc tcagaatgag actctctaac ctacatcaga   8040

accagagaag aatgtgcact atgtgggtct gttatcatta ttttctttta gtttgtatct   8100

ttttggagat ttatccaagt gccagattac tcagtgctat aattttcttt tagttaaaca   8160

aagggggtca gacagacatt gcatcatcca gacatgcctt gttggacatg tagaatccga   8220

tggagcactg cacaccagaa tgattggcca atgagcagct tctctccctg aaacaataac   8280

tgcccatttg gcaaagggaa agatgacaat aatcagaaga agaaaatgaa tgggatgcat   8340

accatagacg aacgaggcgg agactattgc gggaatctta ctgttcagga gctgttccta   8400

gaactaactc ccttactgtc attgatgtgc attccactct gtgcttttct gtacaaccat   8460

tcaagtttta atttcccagg tgaaccatct ttatctgcca ttaccacaag ctttcaagtt   8520

tccagttatt ttcatcatca taaccagtac ggtgctatta tttacctatg tacgtgtagt   8580

tatgtataat tttgtaatta gttacaatgg taaaaaaaat caaaatatat aaaaagtgat   8640

ttgtacagaa ctttatttta gctctttttt aaaaatgatt tgcatggtta gaaaacggcg   8700

aggacagcca ggggagggaa gggcctctag ggaactttgc actttctata cctttgtact   8760

atgcactgcc ctattgattc tacacccaat aatgatatta cttgaaccca tctgtaagaa   8820

actgcttcgg aaattcattt gtgtgtatgt aaataacaca acatagaaac aggaagggaa   8880

aaaagtctgc agtaatgcac gtattttttt tctttcctgt ttattttcgg ttttgcttta   8940

agtcctttta tttttaattc cctttttgtt tttctttttg ggttttggtt ccttttgggt   9000

ttatgggtgc cctgatactc cagcagagat cagaaggcta cagatccatt ctatccatcc   9060

gttatgtggc tttgccatcc cagcttggag tgtctttaca aagataataa cagttgtgtt   9120

ctttgctctc gttttggatg catagactga aaaattaaaa caaataactt gtaaaatggc   9180

ttgttaaaaa atacaattac ctctaattag tagtacgcgt aaatgtttta cagaatgaaa   9240

ggcgtgcttt ttattttctt acttcgttac attggtggcg aaagaagtct gtatgaaaat   9300

cagttctttg ctgacacaag ttccatttgt tacaaatgaa ttctaataaa aatgtcagtg   9360

ttatgca                                                             9367


<210>  6009
<211>  1656
<212>  PRT
<213>  Homo sapiens

<400>  6009

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Asp 
        515                 520                 525


Met Ile Ile Ser Gly Leu Gln Pro Glu Thr Ser Tyr Ser Leu Thr Val 
    530                 535                 540


Thr Ala Tyr Thr Thr Lys Gly Asp Gly Ala Arg Ser Lys Pro Lys Leu 
545                 550                 555                 560


Val Ser Thr Thr Gly Ala Val Pro Gly Lys Pro Arg Leu Val Ile Asn 
                565                 570                 575


His Thr Gln Met Asn Thr Ala Leu Ile Gln Trp His Pro Pro Val Asp 
            580                 585                 590


Thr Phe Gly Pro Leu Gln Gly Tyr Arg Leu Lys Phe Gly Arg Lys Asp 
        595                 600                 605


Met Glu Pro Leu Thr Thr Leu Glu Phe Ser Glu Lys Glu Asp His Phe 
    610                 615                 620


Thr Ala Thr Asp Ile His Lys Gly Ala Ser Tyr Val Phe Arg Leu Ser 
625                 630                 635                 640


Ala Arg Asn Lys Val Gly Phe Gly Glu Glu Met Val Lys Glu Ile Ser 
                645                 650                 655


Ile Pro Glu Glu Val Pro Thr Gly Phe Pro Gln Asn Leu His Ser Glu 
            660                 665                 670


Gly Thr Thr Ser Thr Ser Val Gln Leu Ser Trp Gln Pro Pro Val Leu 
        675                 680                 685


Ala Glu Arg Asn Gly Ile Ile Thr Lys Tyr Thr Leu Leu Tyr Arg Asp 
    690                 695                 700


Ile Asn Ile Pro Leu Leu Pro Met Glu Gln Leu Ile Val Pro Ala Asp 
705                 710                 715                 720


Thr Thr Met Thr Leu Thr Gly Leu Lys Pro Asp Thr Thr Tyr Asp Val 
                725                 730                 735


Lys Val Arg Ala His Thr Ser Lys Gly Pro Gly Pro Tyr Ser Pro Ser 
            740                 745                 750


Val Gln Phe Arg Thr Leu Pro Val Asp Gln Val Phe Ala Lys Asn Phe 
        755                 760                 765


His Val Lys Ala Val Met Lys Thr Ser Val Leu Leu Ser Trp Glu Ile 
    770                 775                 780


Pro Glu Asn Tyr Asn Ser Ala Met Pro Phe Lys Ile Leu Tyr Asp Asp 
785                 790                 795                 800


Gly Lys Met Val Glu Glu Val Asp Gly Arg Ala Thr Gln Lys Leu Ile 
                805                 810                 815


Val Asn Leu Lys Pro Glu Lys Ser Tyr Ser Phe Val Leu Thr Asn Arg 
            820                 825                 830


Gly Asn Ser Ala Gly Gly Leu Gln His Arg Val Thr Ala Lys Thr Ala 
        835                 840                 845


Pro Asp Val Leu Arg Thr Lys Pro Ala Phe Ile Gly Lys Thr Asn Leu 
    850                 855                 860


Asp Gly Met Ile Thr Val Gln Leu Pro Glu Val Pro Ala Asn Glu Asn 
865                 870                 875                 880


Ile Lys Gly Tyr Tyr Ile Ile Ile Val Pro Leu Lys Lys Ser Arg Gly 
                885                 890                 895


Lys Phe Ile Lys Pro Trp Glu Ser Pro Asp Glu Met Glu Leu Asp Glu 
            900                 905                 910


Leu Leu Lys Glu Ile Ser Arg Lys Arg Arg Ser Ile Arg Tyr Gly Arg 
        915                 920                 925


Glu Val Glu Leu Lys Pro Tyr Ile Ala Ala His Phe Asp Val Leu Pro 
    930                 935                 940


Thr Glu Phe Thr Leu Gly Asp Asp Lys His Tyr Gly Gly Phe Thr Asn 
945                 950                 955                 960


Lys Gln Leu Gln Ser Gly Gln Glu Tyr Val Phe Phe Val Leu Ala Val 
                965                 970                 975


Met Glu His Ala Glu Ser Lys Met Tyr Ala Thr Ser Pro Tyr Ser Asp 
            980                 985                 990


Pro Val Val Ser Met Asp Leu Asp Pro Gln Pro Ile Thr Asp Glu Glu 
        995                 1000                1005


Glu Gly Leu Ile Trp Val Val Gly Pro Val Leu Ala Val Val Phe Ile 
    1010                1015                1020


Ile Cys Ile Val Ile Ala Ile Leu Leu Tyr Lys Arg Lys Arg Ala Glu 
1025                1030                1035                1040


Ser Asp Ser Arg Lys Ser Ser Ile Pro Asn Asn Lys Glu Ile Pro Ser 
                1045                1050                1055


His His Pro Thr Asp Pro Val Glu Leu Arg Arg Leu Asn Phe Gln Thr 
            1060                1065                1070


Pro Gly Met Ala Ser His Pro Pro Ile Pro Ile Leu Glu Leu Ala Asp 
        1075                1080                1085


His Ile Glu Arg Leu Lys Ala Asn Asp Asn Leu Lys Phe Ser Gln Glu 
    1090                1095                1100


Tyr Glu Ser Ile Asp Pro Gly Gln Gln Phe Thr Trp Glu His Ser Asn 
1105                1110                1115                1120


Leu Glu Val Asn Lys Pro Lys Asn Arg Tyr Ala Asn Val Ile Ala Tyr 
                1125                1130                1135


Asp His Ser Arg Val Leu Leu Ser Ala Ile Glu Gly Ile Pro Gly Ser 
            1140                1145                1150


Asp Tyr Val Asn Ala Asn Tyr Ile Asp Gly Tyr Arg Lys Gln Asn Ala 
        1155                1160                1165


Tyr Ile Ala Thr Gln Gly Ser Leu Pro Glu Thr Phe Gly Asp Phe Trp 
    1170                1175                1180


Arg Met Ile Trp Glu Gln Arg Ser Ala Thr Val Val Met Met Thr Lys 
1185                1190                1195                1200


Leu Glu Glu Arg Ser Arg Val Lys Cys Asp Gln Tyr Trp Pro Ser Arg 
                1205                1210                1215


Gly Thr Glu Thr His Gly Leu Val Gln Val Thr Leu Leu Asp Thr Val 
            1220                1225                1230


Glu Leu Ala Thr Tyr Cys Val Arg Thr Phe Ala Leu Tyr Lys Asn Gly 
        1235                1240                1245


Ser Ser Glu Lys Arg Glu Val Arg Gln Phe Gln Phe Thr Ala Trp Pro 
    1250                1255                1260


Asp His Gly Val Pro Glu His Pro Thr Pro Phe Leu Ala Phe Leu Arg 
1265                1270                1275                1280


Arg Val Lys Thr Cys Asn Pro Pro Asp Ala Gly Pro Met Val Val His 
                1285                1290                1295


Cys Ser Ala Gly Val Gly Arg Thr Gly Cys Phe Ile Val Ile Asp Ala 
            1300                1305                1310


Met Leu Glu Arg Ile Lys His Glu Lys Thr Val Asp Ile Tyr Gly His 
        1315                1320                1325


Val Thr Leu Met Arg Ala Gln Arg Asn Tyr Met Val Gln Thr Glu Asp 
    1330                1335                1340


Gln Tyr Ile Phe Ile His Asp Ala Leu Leu Glu Ala Val Thr Cys Gly 
1345                1350                1355                1360


Asn Thr Glu Val Pro Ala Arg Asn Leu Tyr Ala Tyr Ile Gln Lys Leu 
                1365                1370                1375


Thr Gln Ile Glu Thr Gly Glu Asn Val Thr Gly Met Glu Leu Glu Phe 
            1380                1385                1390


Lys Arg Leu Ala Ser Ser Lys Ala His Thr Ser Arg Phe Ile Ser Ala 
        1395                1400                1405


Asn Leu Pro Cys Asn Lys Phe Lys Asn Arg Leu Val Asn Ile Met Pro 
    1410                1415                1420


Tyr Glu Ser Thr Arg Val Cys Leu Gln Pro Ile Arg Gly Val Glu Gly 
1425                1430                1435                1440


Ser Asp Tyr Ile Asn Ala Ser Phe Ile Asp Gly Tyr Arg Gln Gln Lys 
                1445                1450                1455


Ala Tyr Ile Ala Thr Gln Gly Pro Leu Ala Glu Thr Thr Glu Asp Phe 
            1460                1465                1470


Trp Arg Met Leu Trp Glu His Asn Ser Thr Ile Val Val Met Leu Thr 
        1475                1480                1485


Lys Leu Arg Glu Met Gly Arg Glu Lys Cys His Gln Tyr Trp Pro Ala 
    1490                1495                1500


Glu Arg Ser Ala Arg Tyr Gln Tyr Phe Val Val Asp Pro Met Ala Glu 
1505                1510                1515                1520


Tyr Asn Met Pro Gln Tyr Ile Leu Arg Glu Phe Lys Val Thr Asp Ala 
                1525                1530                1535


Arg Asp Gly Gln Ser Arg Thr Val Arg Gln Phe Gln Phe Thr Asp Trp 
            1540                1545                1550


Pro Glu Gln Gly Val Pro Lys Ser Gly Glu Gly Phe Ile Asp Phe Ile 
        1555                1560                1565


Gly Gln Val His Lys Thr Lys Glu Gln Phe Gly Gln Asp Gly Pro Ile 
    1570                1575                1580


Ser Val His Cys Ser Ala Gly Val Gly Arg Thr Gly Val Phe Ile Thr 
1585                1590                1595                1600


Leu Ser Ile Val Leu Glu Arg Met Arg Tyr Glu Gly Val Val Asp Ile 
                1605                1610                1615


Phe Gln Thr Val Lys Met Leu Arg Thr Gln Arg Pro Ala Met Val Gln 
            1620                1625                1630


Thr Glu Asp Gln Tyr Gln Phe Ser Tyr Arg Ala Ala Leu Glu Tyr Leu 
        1635                1640                1645


Gly Ser Phe Asp His Tyr Ala Thr 
    1650                1655


<210>  6010
<211>  9394
<212>  DNA
<213>  Homo sapiens

<400>  6010
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aaagccgtca gctcctcctc   2100

aagacattag ttgcaccagc ccaagttcca ctagtatttt ggtaagttgg caacctccac   2160

cagtggaaaa acagaatggc attatcactg aatactccat caagtacact gcagtggatg   2220

gggaagatga caagcctcac gagattttgg gaattccttc ggacactacc aaataccttt   2280

tggaacagct ggaaaaatgg actgaatacc ggatcactgt gacagcccat acagatgtcg   2340

gccctggccc tgagagcttg tccgtgttga ttcgaaccaa tgaagatgtt cctagtggtc   2400

ctcctcgcaa agtcgaggta gaggctgtca actcaacatc tgttaaagtc tcatggcgct   2460

cacccgtgcc caataaacag catggccaga taagaggata tcaggtgcat tatgtgagga   2520

tggaaaatgg tgagcccaag ggccagccca tgctgaaaga tgtcatgctg gctgatgcac   2580

agtgggaatt tgatgatact actgaacatg acatgatcat ttctgggctc cagcctgaaa   2640

cttcctactc cctcaccgtc acagcctaca caaccaaagg agatggtgct cgcagcaagc   2700

ccaaactggt gtccaccact ggggcagttc cagggaaacc tcggcttgtg attaaccaca   2760

ctcagatgaa tactgctctt attcagtggc accctccggt ggacacattt ggacctcttc   2820

agggctaccg tctaaaattt ggccgcaagg atatggagcc acttactact cttgagttct   2880

ctgaaaaaga agatcacttt acagctacag acatccacaa gggagcatca tacgtcttca   2940

ggctctcagc cagaaacaaa gtgggctttg gggaggagat ggtgaaggag atttccattc   3000

cagaagaagt accaactgga ttccctcaaa accttcactc agaaggcacc acttcaacct   3060

ccgtccagtt atcttggcaa ccacctgtcc tggcagagag aaatggcatt atcaccaagt   3120

atacccttct ttatagggat atcaacatcc cccttctccc gatggagcag cttattgttc   3180

cagctgacac cactatgaca ctcactggct taaaaccaga taccacatac gatgtaaaag   3240

tacgtgctca tacgagcaaa gggcccgggc catatagtcc cagtgtccag ttcaggacac   3300

tgcctgtgga tcaagtgttt gcaaaaaatt ttcatgtcaa agcagtaatg aagacttccg   3360

tgttgctgtc ttgggagatt ccagagaatt ataactccgc catgcctttc aaaattcttt   3420

atgatgatgg gaaaatggta gaagaagtgg atggccgagc cacacagaag ttaattgtca   3480

acctgaagcc tgagaaatca tattcatttg tgctgacaaa tcgtggaaac agtgctggtg   3540

ggctgcagca cagggtcacg gcaaagactg caccagatgt attacgtacc aagcctgcct   3600

tcattgggaa gaccaacttg gatggcatga ttactgtgca actgcctgaa gtacctgcaa   3660

atgagaatat aaaaggttac tacataataa ttgtgccttt gaagaaatct cgcgggaaat   3720

ttatcaagcc atgggagagt ccagatgaaa tggaattaga tgagctgctt aaggagatat   3780

ctaggaagcg cagaagcatc cgttatggga gagaagttga attaaagcca tatattgccg   3840

ctcactttga tgtccttccc actgagttca ccctggggga tgacaagcat tatggtggat   3900

ttacaaacaa gcaactccaa agtggtcaag aatatgtctt ctttgtgtta gcagtaatgg   3960

aacatgcaga gtctaagatg tatgcaacca gcccttactc cgaccccgtg gtgtcaatgg   4020

atctggatcc gcagccaatc acggatgaag aagaaggctt gatctgggtt gtaggtcctg   4080

tccttgcagt ggtctttatc atctgcattg tcattgctat tcttctttat aaaaggaaga   4140

gggcagagtc cgactctaga aaaagcagca taccgaacaa taaggagatc ccttcacacc   4200

acccaacaga ccctgtagaa ctgaggcgcc ttaactttca aacaccgggt atggctagcc   4260

atcctccaat acccatcttg gaacttgcag accacattga aagattgaaa gcaaatgaca   4320

acttgaagtt ttcccaggaa tatgagtcaa ttgaccctgg ccagcagttc acttgggaac   4380

attcaaactt ggaagtaaac aaaccaaaga atagatacgc gaatgtaatc gcatatgatc   4440

attcccgggt tctcctatca gctatagaag ggatcccagg aagtgactat gtgaatgcca   4500

actacataga tgggtatagg aagcaaaatg cctatattgc aacacaggga tctctccccg   4560

aaacatttgg ggacttttgg agaatgatat gggaacaacg gagtgccaca gttgtcatga   4620

tgacaaaact agaagaaaga tcaagggtga agtgtgacca gtattggcct agcagaggca   4680

cagaaaccca cggactcgtt caagtaacgc tgcttgatac tgtggagctg gccacatatt   4740

gtgttcgaac atttgcactt tacaagaatg gttcaagtga gaagagagaa gtgagacaat   4800

tccagttcac cgcctggcct gatcatggtg ttccagaaca ccctacacct tttctagctt   4860

tcttacgtag agtcaaaacc tgtaaccctc ccgatgctgg tccgatggtt gtgcactgca   4920

gtgcgggagt tggccggact ggttgcttca tcgtcataga tgccatgtta gaaagaataa   4980

agcatgaaaa aactgtagat atttatggcc atgtaacttt aatgagagcc cagaggaact   5040

atatggttca aacagaagac caatacatct ttatccatga tgcactgtta gaagcagtga   5100

cttgtggaaa taccgaagtg ccagctagaa acttgtatgc ctacattcag aagctgacac   5160

aaatagaaac gggagagaat gtcacaggaa tggagctcga atttaagcgt ctagccagct   5220

caaaagctca cacctcaagg tttatcagtg ccaatcttcc atgtaataaa ttcaaaaatc   5280

gccttgttaa tattatgcca tatgaatcca caagggtatg cctgcagcct atccgtggag   5340

tagaaggatc tgattacatc aatgccagtt ttattgatgg atacagacaa cagaaagcct   5400

acatcgctac ccaggggccc ttggcagaga ccactgaaga cttctggcgg atgctctggg   5460

aacacaattc caccatagtt gtgatgctca ccaagctgcg tgaaatgggc agagagaaat   5520

gtcaccaata ctggccagca gaacggtctg caagatacca gtactttgtt gtagatccca   5580

tggctgagta caacatgcca cagtatatcc taagggaatt caaggtcaca gatgccaggg   5640

acggccagtc ccgaacagta aggcagttcc agttcactga ctggccagag caaggagtgc   5700

caaagtccgg agaaggattt attgacttca tcggccaagt ccataaaaca aaagaacagt   5760

ttggccaaga tggacccatt tcagtccatt gcagcgcggg cgttggaaga actggagtct   5820

tcataacgct aagcattgtt ttggaaagaa tgagatatga aggagttgta gatatcttcc   5880

agactgtcaa aatgttaaga acacaacgac cagctatggt acagacagag gatcaatatc   5940

agttttccta tcgtgccgca ctagagtacc tgggcagctt tgaccactat gcaacgtaga   6000

aacccctgac ccattctgga tttttactac aggcccttca atatccatgg agtctcttct   6060

gagccataca gggcacttga gaagtccttc ttaacttcta gctaacaact acttagtggg   6120

actattacac acaaaacaaa ttaaaaacaa attattccag gtggaccaag aatctgcttt   6180

gacatcgccc cttcccacca tactgctcat aataacattt tagggggaaa ggggagggaa   6240

tgtttaaaaa gaaagtcctt gatttagttt tttagtattg taaagatact gctgacctgt   6300

gcttcatttc taactgtgta aacttttttt taacaaaatg tatcattcga taaagtgaat   6360

tttaaaaaag ttacataact cttcattttt ttatttccaa atcgtaggtt tttttaagct   6420

gtagaactgt tatctgtaat atcttgctgt agaaatatca aatcatttga aaatttgcac   6480

atttttgtgc aaaactcaat ctacagtatc agtctcgtca gatatattaa ttttacactt   6540

cagttttgat tggtgagaaa gtacccattc tcttcaaata atcaaagata attattattt   6600

tgttttgttt ttggaatcaa cagggaggcg caaagtataa agttgctgct aacatatata   6660

catatatatc catattttat aagggtgtct atgtatatat agacagtgtg tccacacaaa   6720

aaatagatac agttatcagt cagtcagttc ttccatgatt tagttttttt aaacgtagaa   6780

aagctattgt aaacatctct ttccatttat tcttaatttt ttgacatatt ggtatttctt   6840

taaagggaaa tgaggaatgc acatcagtga ttgattgtca aacctcaccc cctgatttcc   6900

tacctaatct acccccacct aaccaatcaa tcacatccac aaattgtttt gtttgtttgt   6960

tagtcaggct tccaacaaag ttcaatattt ctaacactct agtgcaataa aaattattat   7020

taaatagcta agaggtgtgc atgtgggaaa ggtcagtgca tatcccttta ggaggggaga   7080

atgttgtaat atatcagcta tcgagttgtt taaaaaaagt gtattcaatc gtatattgtc   7140

tatagtatgt gctatgaaat ttgcatttat gatatgtaac aggggcaaag ccaaattcat   7200

gttactctgt tcagtcagaa acattttgtg gcatacagca ttcctgggaa gtgctgtact   7260

ttgtttcgtt ttggttttag ttttgcattt agagtgcctt ataattgatg cctattttaa   7320

tagcatttct ttttagcttt tggttcgtat ttccattcac tgttcgtatc tgttactttc   7380

tattaaagca ttatctgttt accacatgta caaaaactct ttgaataata tgcattccta   7440

gttttcagcc aagtcgggga tgttagtgat tgtaccagcc caaagcactt ggataatcag   7500

ggcccttctt ccttttataa tcaatcatca acatcagaaa aagctacttg ttttatttat   7560

attcccttcc aaatccgctc tggaacatgc agtaactgca ccaaacttat tttagtaaca   7620

aatatcattg gcaactttgg aatatatttg atattccatt aggatttttc taaaagggga   7680

aataaactat atatatatat gtatcttacc cccaattctt ccaacagaat ttctatagga   7740

agccatggat gatggcataa gtttgccaca tattacatga ttttaaataa tcctcaaaat   7800

acccaaggaa ctcttaaaga gttttggtat gagtatacta ctttggttta attttagctt   7860

catggatgtt ctgcatggaa ggatttttgt tttccacatt ttcccattgc tagcagagtg   7920

aaatccaaga gaccaaacat ttgcaagcat tgtatttgag cacttttgta aaaaacaaag   7980

aaaaagaaaa aaaagaaaat atatataata ctaaaaaaaa gtatctagaa ggctacctca   8040

gaatgagact ctctaaccta catcagaacc agagaagaat gtgcactatg tgggtctgtt   8100

atcattattt tcttttagtt tgtatctttt tggagattta tccaagtgcc agattactca   8160

gtgctataat tttcttttag ttaaacaaag ggggtcagac agacattgca tcatccagac   8220

atgccttgtt ggacatgtag aatccgatgg agcactgcac accagaatga ttggccaatg   8280

agcagcttct ctccctgaaa caataactgc ccatttggca aagggaaaga tgacaataat   8340

cagaagaaga aaatgaatgg gatgcatacc atagacgaac gaggcggaga ctattgcggg   8400

aatcttactg ttcaggagct gttcctagaa ctaactccct tactgtcatt gatgtgcatt   8460

ccactctgtg cttttctgta caaccattca agttttaatt tcccaggtga accatcttta   8520

tctgccatta ccacaagctt tcaagtttcc agttattttc atcatcataa ccagtacggt   8580

gctattattt acctatgtac gtgtagttat gtataatttt gtaattagtt acaatggtaa   8640

aaaaaatcaa aatatataaa aagtgatttg tacagaactt tattttagct cttttttaaa   8700

aatgatttgc atggttagaa aacggcgagg acagccaggg gagggaaggg cctctaggga   8760

actttgcact ttctatacct ttgtactatg cactgcccta ttgattctac acccaataat   8820

gatattactt gaacccatct gtaagaaact gcttcggaaa ttcatttgtg tgtatgtaaa   8880

taacacaaca tagaaacagg aagggaaaaa agtctgcagt aatgcacgta ttttttttct   8940

ttcctgttta ttttcggttt tgctttaagt ccttttattt ttaattccct ttttgttttt   9000

ctttttgggt tttggttcct tttgggttta tgggtgccct gatactccag cagagatcag   9060

aaggctacag atccattcta tccatccgtt atgtggcttt gccatcccag cttggagtgt   9120

ctttacaaag ataataacag ttgtgttctt tgctctcgtt ttggatgcat agactgaaaa   9180

attaaaacaa ataacttgta aaatggcttg ttaaaaaata caattacctc taattagtag   9240

tacgcgtaaa tgttttacag aatgaaaggc gtgcttttta ttttcttact tcgttacatt   9300

ggtggcgaaa gaagtctgta tgaaaatcag ttctttgctg acacaagttc catttgttac   9360

aaatgaattc taataaaaat gtcagtgtta tgca                               9394


<210>  6011
<211>  1665
<212>  PRT
<213>  Homo sapiens

<400>  6011

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Trp 
        515                 520                 525


Glu Phe Asp Asp Thr Thr Glu His Asp Met Ile Ile Ser Gly Leu Gln 
    530                 535                 540


Pro Glu Thr Ser Tyr Ser Leu Thr Val Thr Ala Tyr Thr Thr Lys Gly 
545                 550                 555                 560


Asp Gly Ala Arg Ser Lys Pro Lys Leu Val Ser Thr Thr Gly Ala Val 
                565                 570                 575


Pro Gly Lys Pro Arg Leu Val Ile Asn His Thr Gln Met Asn Thr Ala 
            580                 585                 590


Leu Ile Gln Trp His Pro Pro Val Asp Thr Phe Gly Pro Leu Gln Gly 
        595                 600                 605


Tyr Arg Leu Lys Phe Gly Arg Lys Asp Met Glu Pro Leu Thr Thr Leu 
    610                 615                 620


Glu Phe Ser Glu Lys Glu Asp His Phe Thr Ala Thr Asp Ile His Lys 
625                 630                 635                 640


Gly Ala Ser Tyr Val Phe Arg Leu Ser Ala Arg Asn Lys Val Gly Phe 
                645                 650                 655


Gly Glu Glu Met Val Lys Glu Ile Ser Ile Pro Glu Glu Val Pro Thr 
            660                 665                 670


Gly Phe Pro Gln Asn Leu His Ser Glu Gly Thr Thr Ser Thr Ser Val 
        675                 680                 685


Gln Leu Ser Trp Gln Pro Pro Val Leu Ala Glu Arg Asn Gly Ile Ile 
    690                 695                 700


Thr Lys Tyr Thr Leu Leu Tyr Arg Asp Ile Asn Ile Pro Leu Leu Pro 
705                 710                 715                 720


Met Glu Gln Leu Ile Val Pro Ala Asp Thr Thr Met Thr Leu Thr Gly 
                725                 730                 735


Leu Lys Pro Asp Thr Thr Tyr Asp Val Lys Val Arg Ala His Thr Ser 
            740                 745                 750


Lys Gly Pro Gly Pro Tyr Ser Pro Ser Val Gln Phe Arg Thr Leu Pro 
        755                 760                 765


Val Asp Gln Val Phe Ala Lys Asn Phe His Val Lys Ala Val Met Lys 
    770                 775                 780


Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu Asn Tyr Asn Ser Ala 
785                 790                 795                 800


Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys Met Val Glu Glu Val 
                805                 810                 815


Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn Leu Lys Pro Glu Lys 
            820                 825                 830


Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn Ser Ala Gly Gly Leu 
        835                 840                 845


Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp Val Leu Arg Thr Lys 
    850                 855                 860


Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly Met Ile Thr Val Gln 
865                 870                 875                 880


Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys Gly Tyr Tyr Ile Ile 
                885                 890                 895


Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe Ile Lys Pro Trp Glu 
            900                 905                 910


Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu Lys Glu Ile Ser Arg 
        915                 920                 925


Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val Glu Leu Lys Pro Tyr 
    930                 935                 940


Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu Phe Thr Leu Gly Asp 
945                 950                 955                 960


Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln Leu Gln Ser Gly Gln 
                965                 970                 975


Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu His Ala Glu Ser Lys 
            980                 985                 990


Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val Val Ser Met Asp Leu 
        995                 1000                1005


Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly Leu Ile Trp Val Val 
    1010                1015                1020


Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys Ile Val Ile Ala Ile 
1025                1030                1035                1040


Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp Ser Arg Lys Ser Ser 
                1045                1050                1055


Ile Pro Asn Asn Lys Glu Ile Pro Ser His His Pro Thr Asp Pro Val 
            1060                1065                1070


Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly Met Ala Ser His Pro 
        1075                1080                1085


Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile Glu Arg Leu Lys Ala 
    1090                1095                1100


Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu Ser Ile Asp Pro Gly 
1105                1110                1115                1120


Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu Val Asn Lys Pro Lys 
                1125                1130                1135


Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His Ser Arg Val Leu Leu 
            1140                1145                1150


Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr Val Asn Ala Asn Tyr 
        1155                1160                1165


Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile Ala Thr Gln Gly Ser 
    1170                1175                1180


Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met Ile Trp Glu Gln Arg 
1185                1190                1195                1200


Ser Ala Thr Val Val Met Met Thr Lys Leu Glu Glu Arg Ser Arg Val 
                1205                1210                1215


Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr Glu Thr His Gly Leu 
            1220                1225                1230


Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu Ala Thr Tyr Cys Val 
        1235                1240                1245


Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser Glu Lys Arg Glu Val 
    1250                1255                1260


Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His Gly Val Pro Glu His 
1265                1270                1275                1280


Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val Lys Thr Cys Asn Pro 
                1285                1290                1295


Pro Asp Ala Gly Pro Met Val Val His Cys Ser Ala Gly Val Gly Arg 
            1300                1305                1310


Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu Glu Arg Ile Lys His 
        1315                1320                1325


Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr Leu Met Arg Ala Gln 
    1330                1335                1340


Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr Ile Phe Ile His Asp 
1345                1350                1355                1360


Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr Glu Val Pro Ala Arg 
                1365                1370                1375


Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln Ile Glu Thr Gly Glu 
            1380                1385                1390


Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg Leu Ala Ser Ser Lys 
        1395                1400                1405


Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu Pro Cys Asn Lys Phe 
    1410                1415                1420


Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu Ser Thr Arg Val Cys 
1425                1430                1435                1440


Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp Tyr Ile Asn Ala Ser 
                1445                1450                1455


Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr Ile Ala Thr Gln Gly 
            1460                1465                1470


Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg Met Leu Trp Glu His 
        1475                1480                1485


Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu Arg Glu Met Gly Arg 
    1490                1495                1500


Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg Ser Ala Arg Tyr Gln 
1505                1510                1515                1520


Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn Met Pro Gln Tyr Ile 
                1525                1530                1535


Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp Gly Gln Ser Arg Thr 
            1540                1545                1550


Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu Gln Gly Val Pro Lys 
        1555                1560                1565


Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln Val His Lys Thr Lys 
    1570                1575                1580


Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val His Cys Ser Ala Gly 
1585                1590                1595                1600


Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser Ile Val Leu Glu Arg 
                1605                1610                1615


Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln Thr Val Lys Met Leu 
            1620                1625                1630


Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu Asp Gln Tyr Gln Phe 
        1635                1640                1645


Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser Phe Asp His Tyr Ala 
    1650                1655                1660


Thr 
1665


<210>  6012
<211>  9382
<212>  DNA
<213>  Homo sapiens

<400>  6012
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcagt tcgccgtgtc ccaccaagat    960

tctctatccc acccactaat catgaaatca tgccaggcgg aagcgttaat atcacctgtg   1020

tggccgtggg gtcaccaatg ccttatgtaa agtggatgtt gggggcagaa gatctgacac   1080

ctgaagatga tatgccaata ggaagaaatg tgctagaact gaatgatgta agacagtcag   1140

caaattacac ctgtgttgct atgtcaacac tgggtgtcat tgaagcaata gcacagatca   1200

ctgtcaaagc cttacccaaa cctccaggaa ctcctgtagt gaccgagagc acagctacaa   1260

gcatcacact gacgtgggac tctgggaacc ctgagcctgt ttcttattac ataattcagc   1320

ataaacctaa aaactctgag gaactttaca aagaaattga tggggtggcg accacacgct   1380

acagtgtcgc tggactaagt ccctactcgg attatgaatt cagggttgtt gctgtcaata   1440

acattgggcg ggggcctccc agcgaacctg tgctaacaca aacctcagag caagcaccat   1500

ccagtgcccc gagggatgtc caggcacgaa tgttgagttc gaccaccatt ttggtacagt   1560

ggaaggaacc tgaagagcca aatggacaga tccaaggata tagagtttat tatacaatgg   1620

atcccactca acatgtcaac aactggatga aacacaatgt agctgacagc caaatcacta   1680

ctattggcaa cttagtgccc cagaaaacat attctgtcaa agtcctggct tttacctcaa   1740

ttggagatgg tcccctttca agtgacatac aagtcatcac tcagacagga gtaccagggc   1800

agccactaaa cttcaaagca gaacctgagt ctgaaacaag tattttgctc tcttggacac   1860

ctccacgttc agataccatt gccaactatg aactggtcta caaagatggg gagcatggag   1920

aggagcaacg aattaccatt gagccaggga catcatatag gctgcaagga ctgaaaccaa   1980

acagcttata ctatttccgt ctggctgcac gctcccctca aggcctgggt gcttctactg   2040

cagaaatatc agctagaacc atgcagtcaa agccgtcagc tcctcctcaa gacattagtt   2100

gcaccagccc aagttccact agtattttgg taagttggca acctccacca gtggaaaaac   2160

agaatggcat tatcactgaa tactccatca agtacactgc agtggatggg gaagatgaca   2220

agcctcacga gattttggga attccttcgg acactaccaa ataccttttg gaacagctgg   2280

aaaaatggac tgaataccgg atcactgtga cagcccatac agatgtcggc cctggccctg   2340

agagcttgtc cgtgttgatt cgaaccaatg aagatgttcc tagtggtcct cctcgcaaag   2400

tcgaggtaga ggctgtcaac tcaacatctg ttaaagtctc atggcgctca cccgtgccca   2460

ataaacagca tggccagata agaggatatc aggtgcatta tgtgaggatg gaaaatggtg   2520

agcccaaggg ccagcccatg ctgaaagatg tcatgctggc tgatgcacag tgggaatttg   2580

atgatactac tgaacatgac atgatcattt ctgggctcca gcctgaaact tcctactccc   2640

tcaccgtcac agcctacaca accaaaggag atggtgctcg cagcaagccc aaactggtgt   2700

ccaccactgg ggcagttcca gggaaacctc ggcttgtgat taaccacact cagatgaata   2760

ctgctcttat tcagtggcac cctccggtgg acacatttgg acctcttcag ggctaccgtc   2820

taaaatttgg ccgcaaggat atggagccac ttactactct tgagttctct gaaaaagaag   2880

atcactttac agctacagac atccacaagg gagcatcata cgtcttcagg ctctcagcca   2940

gaaacaaagt gggctttggg gaggagatgg tgaaggagat ttccattcca gaagaagtac   3000

caactggatt ccctcaaaac cttcactcag aaggcaccac ttcaacctcc gtccagttat   3060

cttggcaacc acctgtcctg gcagagagaa atggcattat caccaagtat acccttcttt   3120

atagggatat caacatcccc cttctcccga tggagcagct tattgttcca gctgacacca   3180

ctatgacact cactggctta aaaccagata ccacatacga tgtaaaagta cgtgctcata   3240

cgagcaaagg gcccgggcca tatagtccca gtgtccagtt caggacactg cctgtggatc   3300

aagtgtttgc aaaaaatttt catgtcaaag cagtaatgaa gacttccgtg ttgctgtctt   3360

gggagattcc agagaattat aactccgcca tgcctttcaa aattctttat gatgatggga   3420

aaatggtaga agaagtggat ggccgagcca cacagaagtt aattgtcaac ctgaagcctg   3480

agaaatcata ttcatttgtg ctgacaaatc gtggaaacag tgctggtggg ctgcagcaca   3540

gggtcacggc aaagactgca ccagatgtat tacgtaccaa gcctgccttc attgggaaga   3600

ccaacttgga tggcatgatt actgtgcaac tgcctgaagt acctgcaaat gagaatataa   3660

aaggttacta cataataatt gtgcctttga agaaatctcg cgggaaattt atcaagccat   3720

gggagagtcc agatgaaatg gaattagatg agctgcttaa ggagatatct aggaagcgca   3780

gaagcatccg ttatgggaga gaagttgaat taaagccata tattgccgct cactttgatg   3840

tccttcccac tgagttcacc ctgggggatg acaagcatta tggtggattt acaaacaagc   3900

aactccaaag tggtcaagaa tatgtcttct ttgtgttagc agtaatggaa catgcagagt   3960

ctaagatgta tgcaaccagc ccttactccg accccgtggt gtcaatggat ctggatccgc   4020

agccaatcac ggatgaagaa gaaggcttga tctgggttgt aggtcctgtc cttgcagtgg   4080

tctttatcat ctgcattgtc attgctattc ttctttataa aaggaagagg gcagagtccg   4140

actctagaaa aagcagcata ccgaacaata aggagatccc ttcacaccac ccaacagacc   4200

ctgtagaact gaggcgcctt aactttcaaa caccgggtat ggctagccat cctccaatac   4260

ccatcttgga acttgcagac cacattgaaa gattgaaagc aaatgacaac ttgaagtttt   4320

cccaggaata tgagtcaatt gaccctggcc agcagttcac ttgggaacat tcaaacttgg   4380

aagtaaacaa accaaagaat agatacgcga atgtaatcgc atatgatcat tcccgggttc   4440

tcctatcagc tatagaaggg atcccaggaa gtgactatgt gaatgccaac tacatagatg   4500

ggtataggaa gcaaaatgcc tatattgcaa cacagggatc tctccccgaa acatttgggg   4560

acttttggag aatgatatgg gaacaacgga gtgccacagt tgtcatgatg acaaaactag   4620

aagaaagatc aagggtgaag tgtgaccagt attggcctag cagaggcaca gaaacccacg   4680

gactcgttca agtaacgctg cttgatactg tggagctggc cacatattgt gttcgaacat   4740

ttgcacttta caagaatggt tcaagtgaga agagagaagt gagacaattc cagttcaccg   4800

cctggcctga tcatggtgtt ccagaacacc ctacaccttt tctagctttc ttacgtagag   4860

tcaaaacctg taaccctccc gatgctggtc cgatggttgt gcactgcagt gcgggagttg   4920

gccggactgg ttgcttcatc gtcatagatg ccatgttaga aagaataaag catgaaaaaa   4980

ctgtagatat ttatggccat gtaactttaa tgagagccca gaggaactat atggttcaaa   5040

cagaagacca atacatcttt atccatgatg cactgttaga agcagtgact tgtggaaata   5100

ccgaagtgcc agctagaaac ttgtatgcct acattcagaa gctgacacaa atagaaacgg   5160

gagagaatgt cacaggaatg gagctcgaat ttaagcgtct agccagctca aaagctcaca   5220

cctcaaggtt tatcagtgcc aatcttccat gtaataaatt caaaaatcgc cttgttaata   5280

ttatgccata tgaatccaca agggtatgcc tgcagcctat ccgtggagta gaaggatctg   5340

attacatcaa tgccagtttt attgatggat acagacaaca gaaagcctac atcgctaccc   5400

aggggccctt ggcagagacc actgaagact tctggcggat gctctgggaa cacaattcca   5460

ccatagttgt gatgctcacc aagctgcgtg aaatgggcag agagaaatgt caccaatact   5520

ggccagcaga acggtctgca agataccagt actttgttgt agatcccatg gctgagtaca   5580

acatgccaca gtatatccta agggaattca aggtcacaga tgccagggac ggccagtccc   5640

gaacagtaag gcagttccag ttcactgact ggccagagca aggagtgcca aagtccggag   5700

aaggatttat tgacttcatc ggccaagtcc ataaaacaaa agaacagttt ggccaagatg   5760

gacccatttc agtccattgc agcgcgggcg ttggaagaac tggagtcttc ataacgctaa   5820

gcattgtttt ggaaagaatg agatatgaag gagttgtaga tatcttccag actgtcaaaa   5880

tgttaagaac acaacgacca gctatggtac agacagagga tcaatatcag ttttcctatc   5940

gtgccgcact agagtacctg ggcagctttg accactatgc aacgtagaaa cccctgaccc   6000

attctggatt tttactacag gcccttcaat atccatggag tctcttctga gccatacagg   6060

gcacttgaga agtccttctt aacttctagc taacaactac ttagtgggac tattacacac   6120

aaaacaaatt aaaaacaaat tattccaggt ggaccaagaa tctgctttga catcgcccct   6180

tcccaccata ctgctcataa taacatttta gggggaaagg ggagggaatg tttaaaaaga   6240

aagtccttga tttagttttt tagtattgta aagatactgc tgacctgtgc ttcatttcta   6300

actgtgtaaa ctttttttta acaaaatgta tcattcgata aagtgaattt taaaaaagtt   6360

acataactct tcattttttt atttccaaat cgtaggtttt tttaagctgt agaactgtta   6420

tctgtaatat cttgctgtag aaatatcaaa tcatttgaaa atttgcacat ttttgtgcaa   6480

aactcaatct acagtatcag tctcgtcaga tatattaatt ttacacttca gttttgattg   6540

gtgagaaagt acccattctc ttcaaataat caaagataat tattattttg ttttgttttt   6600

ggaatcaaca gggaggcgca aagtataaag ttgctgctaa catatataca tatatatcca   6660

tattttataa gggtgtctat gtatatatag acagtgtgtc cacacaaaaa atagatacag   6720

ttatcagtca gtcagttctt ccatgattta gtttttttaa acgtagaaaa gctattgtaa   6780

acatctcttt ccatttattc ttaatttttt gacatattgg tatttcttta aagggaaatg   6840

aggaatgcac atcagtgatt gattgtcaaa cctcaccccc tgatttccta cctaatctac   6900

ccccacctaa ccaatcaatc acatccacaa attgttttgt ttgtttgtta gtcaggcttc   6960

caacaaagtt caatatttct aacactctag tgcaataaaa attattatta aatagctaag   7020

aggtgtgcat gtgggaaagg tcagtgcata tccctttagg aggggagaat gttgtaatat   7080

atcagctatc gagttgttta aaaaaagtgt attcaatcgt atattgtcta tagtatgtgc   7140

tatgaaattt gcatttatga tatgtaacag gggcaaagcc aaattcatgt tactctgttc   7200

agtcagaaac attttgtggc atacagcatt cctgggaagt gctgtacttt gtttcgtttt   7260

ggttttagtt ttgcatttag agtgccttat aattgatgcc tattttaata gcatttcttt   7320

ttagcttttg gttcgtattt ccattcactg ttcgtatctg ttactttcta ttaaagcatt   7380

atctgtttac cacatgtaca aaaactcttt gaataatatg cattcctagt tttcagccaa   7440

gtcggggatg ttagtgattg taccagccca aagcacttgg ataatcaggg cccttcttcc   7500

ttttataatc aatcatcaac atcagaaaaa gctacttgtt ttatttatat tcccttccaa   7560

atccgctctg gaacatgcag taactgcacc aaacttattt tagtaacaaa tatcattggc   7620

aactttggaa tatatttgat attccattag gatttttcta aaaggggaaa taaactatat   7680

atatatatgt atcttacccc caattcttcc aacagaattt ctataggaag ccatggatga   7740

tggcataagt ttgccacata ttacatgatt ttaaataatc ctcaaaatac ccaaggaact   7800

cttaaagagt tttggtatga gtatactact ttggtttaat tttagcttca tggatgttct   7860

gcatggaagg atttttgttt tccacatttt cccattgcta gcagagtgaa atccaagaga   7920

ccaaacattt gcaagcattg tatttgagca cttttgtaaa aaacaaagaa aaagaaaaaa   7980

aagaaaatat atataatact aaaaaaaagt atctagaagg ctacctcaga atgagactct   8040

ctaacctaca tcagaaccag agaagaatgt gcactatgtg ggtctgttat cattattttc   8100

ttttagtttg tatctttttg gagatttatc caagtgccag attactcagt gctataattt   8160

tcttttagtt aaacaaaggg ggtcagacag acattgcatc atccagacat gccttgttgg   8220

acatgtagaa tccgatggag cactgcacac cagaatgatt ggccaatgag cagcttctct   8280

ccctgaaaca ataactgccc atttggcaaa gggaaagatg acaataatca gaagaagaaa   8340

atgaatggga tgcataccat agacgaacga ggcggagact attgcgggaa tcttactgtt   8400

caggagctgt tcctagaact aactccctta ctgtcattga tgtgcattcc actctgtgct   8460

tttctgtaca accattcaag ttttaatttc ccaggtgaac catctttatc tgccattacc   8520

acaagctttc aagtttccag ttattttcat catcataacc agtacggtgc tattatttac   8580

ctatgtacgt gtagttatgt ataattttgt aattagttac aatggtaaaa aaaatcaaaa   8640

tatataaaaa gtgatttgta cagaacttta ttttagctct tttttaaaaa tgatttgcat   8700

ggttagaaaa cggcgaggac agccagggga gggaagggcc tctagggaac tttgcacttt   8760

ctataccttt gtactatgca ctgccctatt gattctacac ccaataatga tattacttga   8820

acccatctgt aagaaactgc ttcggaaatt catttgtgtg tatgtaaata acacaacata   8880

gaaacaggaa gggaaaaaag tctgcagtaa tgcacgtatt ttttttcttt cctgtttatt   8940

ttcggttttg ctttaagtcc ttttattttt aattcccttt ttgtttttct ttttgggttt   9000

tggttccttt tgggtttatg ggtgccctga tactccagca gagatcagaa ggctacagat   9060

ccattctatc catccgttat gtggctttgc catcccagct tggagtgtct ttacaaagat   9120

aataacagtt gtgttctttg ctctcgtttt ggatgcatag actgaaaaat taaaacaaat   9180

aacttgtaaa atggcttgtt aaaaaataca attacctcta attagtagta cgcgtaaatg   9240

ttttacagaa tgaaaggcgt gctttttatt ttcttacttc gttacattgg tggcgaaaga   9300

agtctgtatg aaaatcagtt ctttgctgac acaagttcca tttgttacaa atgaattcta   9360

ataaaaatgt cagtgttatg ca                                            9382


<210>  6013
<211>  1665
<212>  PRT
<213>  Homo sapiens

<400>  6013

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Trp 
        515                 520                 525


Glu Phe Asp Asp Thr Thr Glu His Asp Met Ile Ile Ser Gly Leu Gln 
    530                 535                 540


Pro Glu Thr Ser Tyr Ser Leu Thr Val Thr Ala Tyr Thr Thr Lys Gly 
545                 550                 555                 560


Asp Gly Ala Arg Ser Lys Pro Lys Leu Val Ser Thr Thr Gly Ala Val 
                565                 570                 575


Pro Gly Lys Pro Arg Leu Val Ile Asn His Thr Gln Met Asn Thr Ala 
            580                 585                 590


Leu Ile Gln Trp His Pro Pro Val Asp Thr Phe Gly Pro Leu Gln Gly 
        595                 600                 605


Tyr Arg Leu Lys Phe Gly Arg Lys Asp Met Glu Pro Leu Thr Thr Leu 
    610                 615                 620


Glu Phe Ser Glu Lys Glu Asp His Phe Thr Ala Thr Asp Ile His Lys 
625                 630                 635                 640


Gly Ala Ser Tyr Val Phe Arg Leu Ser Ala Arg Asn Lys Val Gly Phe 
                645                 650                 655


Gly Glu Glu Met Val Lys Glu Ile Ser Ile Pro Glu Glu Val Pro Thr 
            660                 665                 670


Gly Phe Pro Gln Asn Leu His Ser Glu Gly Thr Thr Ser Thr Ser Val 
        675                 680                 685


Gln Leu Ser Trp Gln Pro Pro Val Leu Ala Glu Arg Asn Gly Ile Ile 
    690                 695                 700


Thr Lys Tyr Thr Leu Leu Tyr Arg Asp Ile Asn Ile Pro Leu Leu Pro 
705                 710                 715                 720


Met Glu Gln Leu Ile Val Pro Ala Asp Thr Thr Met Thr Leu Thr Gly 
                725                 730                 735


Leu Lys Pro Asp Thr Thr Tyr Asp Val Lys Val Arg Ala His Thr Ser 
            740                 745                 750


Lys Gly Pro Gly Pro Tyr Ser Pro Ser Val Gln Phe Arg Thr Leu Pro 
        755                 760                 765


Val Asp Gln Val Phe Ala Lys Asn Phe His Val Lys Ala Val Met Lys 
    770                 775                 780


Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu Asn Tyr Asn Ser Ala 
785                 790                 795                 800


Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys Met Val Glu Glu Val 
                805                 810                 815


Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn Leu Lys Pro Glu Lys 
            820                 825                 830


Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn Ser Ala Gly Gly Leu 
        835                 840                 845


Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp Val Leu Arg Thr Lys 
    850                 855                 860


Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly Met Ile Thr Val Gln 
865                 870                 875                 880


Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys Gly Tyr Tyr Ile Ile 
                885                 890                 895


Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe Ile Lys Pro Trp Glu 
            900                 905                 910


Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu Lys Glu Ile Ser Arg 
        915                 920                 925


Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val Glu Leu Lys Pro Tyr 
    930                 935                 940


Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu Phe Thr Leu Gly Asp 
945                 950                 955                 960


Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln Leu Gln Ser Gly Gln 
                965                 970                 975


Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu His Ala Glu Ser Lys 
            980                 985                 990


Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val Val Ser Met Asp Leu 
        995                 1000                1005


Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly Leu Ile Trp Val Val 
    1010                1015                1020


Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys Ile Val Ile Ala Ile 
1025                1030                1035                1040


Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp Ser Arg Lys Ser Ser 
                1045                1050                1055


Ile Pro Asn Asn Lys Glu Ile Pro Ser His His Pro Thr Asp Pro Val 
            1060                1065                1070


Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly Met Ala Ser His Pro 
        1075                1080                1085


Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile Glu Arg Leu Lys Ala 
    1090                1095                1100


Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu Ser Ile Asp Pro Gly 
1105                1110                1115                1120


Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu Val Asn Lys Pro Lys 
                1125                1130                1135


Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His Ser Arg Val Leu Leu 
            1140                1145                1150


Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr Val Asn Ala Asn Tyr 
        1155                1160                1165


Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile Ala Thr Gln Gly Ser 
    1170                1175                1180


Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met Ile Trp Glu Gln Arg 
1185                1190                1195                1200


Ser Ala Thr Val Val Met Met Thr Lys Leu Glu Glu Arg Ser Arg Val 
                1205                1210                1215


Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr Glu Thr His Gly Leu 
            1220                1225                1230


Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu Ala Thr Tyr Cys Val 
        1235                1240                1245


Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser Glu Lys Arg Glu Val 
    1250                1255                1260


Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His Gly Val Pro Glu His 
1265                1270                1275                1280


Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val Lys Thr Cys Asn Pro 
                1285                1290                1295


Pro Asp Ala Gly Pro Met Val Val His Cys Ser Ala Gly Val Gly Arg 
            1300                1305                1310


Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu Glu Arg Ile Lys His 
        1315                1320                1325


Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr Leu Met Arg Ala Gln 
    1330                1335                1340


Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr Ile Phe Ile His Asp 
1345                1350                1355                1360


Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr Glu Val Pro Ala Arg 
                1365                1370                1375


Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln Ile Glu Thr Gly Glu 
            1380                1385                1390


Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg Leu Ala Ser Ser Lys 
        1395                1400                1405


Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu Pro Cys Asn Lys Phe 
    1410                1415                1420


Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu Ser Thr Arg Val Cys 
1425                1430                1435                1440


Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp Tyr Ile Asn Ala Ser 
                1445                1450                1455


Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr Ile Ala Thr Gln Gly 
            1460                1465                1470


Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg Met Leu Trp Glu His 
        1475                1480                1485


Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu Arg Glu Met Gly Arg 
    1490                1495                1500


Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg Ser Ala Arg Tyr Gln 
1505                1510                1515                1520


Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn Met Pro Gln Tyr Ile 
                1525                1530                1535


Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp Gly Gln Ser Arg Thr 
            1540                1545                1550


Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu Gln Gly Val Pro Lys 
        1555                1560                1565


Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln Val His Lys Thr Lys 
    1570                1575                1580


Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val His Cys Ser Ala Gly 
1585                1590                1595                1600


Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser Ile Val Leu Glu Arg 
                1605                1610                1615


Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln Thr Val Lys Met Leu 
            1620                1625                1630


Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu Asp Gln Tyr Gln Phe 
        1635                1640                1645


Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser Phe Asp His Tyr Ala 
    1650                1655                1660


Thr 
1665


<210>  6014
<211>  8161
<212>  DNA
<213>  Homo sapiens

<400>  6014
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aatgtttgca aaaaattttc   2100

atgtcaaagc agtaatgaag acttccgtgt tgctgtcttg ggagattcca gagaattata   2160

actccgccat gcctttcaaa attctttatg atgatgggaa aatggtagaa gaagtggatg   2220

gccgagccac acagaagtta attgtcaacc tgaagcctga gaaatcatat tcatttgtgc   2280

tgacaaatcg tggaaacagt gctggtgggc tgcagcacag ggtcacggca aagactgcac   2340

cagatgtatt acgtaccaag cctgccttca ttgggaagac caacttggat ggcatgatta   2400

ctgtgcaact gcctgaagta cctgcaaatg agaatataaa aggttactac ataataattg   2460

tgcctttgaa gaaatctcgc gggaaattta tcaagccatg ggagagtcca gatgaaatgg   2520

aattagatga gctgcttaag gagatatcta ggaagcgcag aagcatccgt tatgggagag   2580

aagttgaatt aaagccatat attgccgctc actttgatgt ccttcccact gagttcaccc   2640

tgggggatga caagcattat ggtggattta caaacaagca actccaaagt ggtcaagaat   2700

atgtcttctt tgtgttagca gtaatggaac atgcagagtc taagatgtat gcaaccagcc   2760

cttactccga ccccgtggtg tcaatggatc tggatccgca gccaatcacg gatgaagaag   2820

aaggcttgat ctgggttgta ggtcctgtcc ttgcagtggt ctttatcatc tgcattgtca   2880

ttgctattct tctttataaa aggaagaggg cagagtccga ctctagaaaa agcagcatac   2940

cgaacaataa ggagatccct tcacaccacc caacagaccc tgtagaactg aggcgcctta   3000

actttcaaac accgggtatg gctagccatc ctccaatacc catcttggaa cttgcagacc   3060

acattgaaag attgaaagca aatgacaact tgaagttttc ccaggaatat gagtcaattg   3120

accctggcca gcagttcact tgggaacatt caaacttgga agtaaacaaa ccaaagaata   3180

gatacgcgaa tgtaatcgca tatgatcatt cccgggttct cctatcagct atagaaggga   3240

tcccaggaag tgactatgtg aatgccaact acatagatgg gtataggaag caaaatgcct   3300

atattgcaac acagggatct ctccccgaaa catttgggga cttttggaga atgatatggg   3360

aacaacggag tgccacagtt gtcatgatga caaaactaga agaaagatca agggtgaagt   3420

gtgaccagta ttggcctagc agaggcacag aaacccacgg actcgttcaa gtaacgctgc   3480

ttgatactgt ggagctggcc acatattgtg ttcgaacatt tgcactttac aagaatggtt   3540

caagtgagaa gagagaagtg agacaattcc agttcaccgc ctggcctgat catggtgttc   3600

cagaacaccc tacacctttt ctagctttct tacgtagagt caaaacctgt aaccctcccg   3660

atgctggtcc gatggttgtg cactgcagtg cgggagttgg ccggactggt tgcttcatcg   3720

tcatagatgc catgttagaa agaataaagc atgaaaaaac tgtagatatt tatggccatg   3780

taactttaat gagagcccag aggaactata tggttcaaac agaagaccaa tacatcttta   3840

tccatgatgc actgttagaa gcagtgactt gtggaaatac cgaagtgcca gctagaaact   3900

tgtatgccta cattcagaag ctgacacaaa tagaaacggg agagaatgtc acaggaatgg   3960

agctcgaatt taagcgtcta gccagctcaa aagctcacac ctcaaggttt atcagtgcca   4020

atcttccatg taataaattc aaaaatcgcc ttgttaatat tatgccatat gaatccacaa   4080

gggtatgcct gcagcctatc cgtggagtag aaggatctga ttacatcaat gccagtttta   4140

ttgatggata cagacaacag aaagcctaca tcgctaccca ggggcccttg gcagagacca   4200

ctgaagactt ctggcggatg ctctgggaac acaattccac catagttgtg atgctcacca   4260

agctgcgtga aatgggcaga gagaaatgtc accaatactg gccagcagaa cggtctgcaa   4320

gataccagta ctttgttgta gatcccatgg ctgagtacaa catgccacag tatatcctaa   4380

gggaattcaa ggtcacagat gccagggacg gccagtcccg aacagtaagg cagttccagt   4440

tcactgactg gccagagcaa ggagtgccaa agtccggaga aggatttatt gacttcatcg   4500

gccaagtcca taaaacaaaa gaacagtttg gccaagatgg acccatttca gtccattgca   4560

gcgcgggcgt tggaagaact ggagtcttca taacgctaag cattgttttg gaaagaatga   4620

gatatgaagg agttgtagat atcttccaga ctgtcaaaat gttaagaaca caacgaccag   4680

ctatggtaca gacagaggat caatatcagt tttcctatcg tgccgcacta gagtacctgg   4740

gcagctttga ccactatgca acgtagaaac ccctgaccca ttctggattt ttactacagg   4800

cccttcaata tccatggagt ctcttctgag ccatacaggg cacttgagaa gtccttctta   4860

acttctagct aacaactact tagtgggact attacacaca aaacaaatta aaaacaaatt   4920

attccaggtg gaccaagaat ctgctttgac atcgcccctt cccaccatac tgctcataat   4980

aacattttag ggggaaaggg gagggaatgt ttaaaaagaa agtccttgat ttagtttttt   5040

agtattgtaa agatactgct gacctgtgct tcatttctaa ctgtgtaaac ttttttttaa   5100

caaaatgtat cattcgataa agtgaatttt aaaaaagtta cataactctt cattttttta   5160

tttccaaatc gtaggttttt ttaagctgta gaactgttat ctgtaatatc ttgctgtaga   5220

aatatcaaat catttgaaaa tttgcacatt tttgtgcaaa actcaatcta cagtatcagt   5280

ctcgtcagat atattaattt tacacttcag ttttgattgg tgagaaagta cccattctct   5340

tcaaataatc aaagataatt attattttgt tttgtttttg gaatcaacag ggaggcgcaa   5400

agtataaagt tgctgctaac atatatacat atatatccat attttataag ggtgtctatg   5460

tatatataga cagtgtgtcc acacaaaaaa tagatacagt tatcagtcag tcagttcttc   5520

catgatttag tttttttaaa cgtagaaaag ctattgtaaa catctctttc catttattct   5580

taattttttg acatattggt atttctttaa agggaaatga ggaatgcaca tcagtgattg   5640

attgtcaaac ctcaccccct gatttcctac ctaatctacc cccacctaac caatcaatca   5700

catccacaaa ttgttttgtt tgtttgttag tcaggcttcc aacaaagttc aatatttcta   5760

acactctagt gcaataaaaa ttattattaa atagctaaga ggtgtgcatg tgggaaaggt   5820

cagtgcatat ccctttagga ggggagaatg ttgtaatata tcagctatcg agttgtttaa   5880

aaaaagtgta ttcaatcgta tattgtctat agtatgtgct atgaaatttg catttatgat   5940

atgtaacagg ggcaaagcca aattcatgtt actctgttca gtcagaaaca ttttgtggca   6000

tacagcattc ctgggaagtg ctgtactttg tttcgttttg gttttagttt tgcatttaga   6060

gtgccttata attgatgcct attttaatag catttctttt tagcttttgg ttcgtatttc   6120

cattcactgt tcgtatctgt tactttctat taaagcatta tctgtttacc acatgtacaa   6180

aaactctttg aataatatgc attcctagtt ttcagccaag tcggggatgt tagtgattgt   6240

accagcccaa agcacttgga taatcagggc ccttcttcct tttataatca atcatcaaca   6300

tcagaaaaag ctacttgttt tatttatatt cccttccaaa tccgctctgg aacatgcagt   6360

aactgcacca aacttatttt agtaacaaat atcattggca actttggaat atatttgata   6420

ttccattagg atttttctaa aaggggaaat aaactatata tatatatgta tcttaccccc   6480

aattcttcca acagaatttc tataggaagc catggatgat ggcataagtt tgccacatat   6540

tacatgattt taaataatcc tcaaaatacc caaggaactc ttaaagagtt ttggtatgag   6600

tatactactt tggtttaatt ttagcttcat ggatgttctg catggaagga tttttgtttt   6660

ccacattttc ccattgctag cagagtgaaa tccaagagac caaacatttg caagcattgt   6720

atttgagcac ttttgtaaaa aacaaagaaa aagaaaaaaa agaaaatata tataatacta   6780

aaaaaaagta tctagaaggc tacctcagaa tgagactctc taacctacat cagaaccaga   6840

gaagaatgtg cactatgtgg gtctgttatc attattttct tttagtttgt atctttttgg   6900

agatttatcc aagtgccaga ttactcagtg ctataatttt cttttagtta aacaaagggg   6960

gtcagacaga cattgcatca tccagacatg ccttgttgga catgtagaat ccgatggagc   7020

actgcacacc agaatgattg gccaatgagc agcttctctc cctgaaacaa taactgccca   7080

tttggcaaag ggaaagatga caataatcag aagaagaaaa tgaatgggat gcataccata   7140

gacgaacgag gcggagacta ttgcgggaat cttactgttc aggagctgtt cctagaacta   7200

actcccttac tgtcattgat gtgcattcca ctctgtgctt ttctgtacaa ccattcaagt   7260

tttaatttcc caggtgaacc atctttatct gccattacca caagctttca agtttccagt   7320

tattttcatc atcataacca gtacggtgct attatttacc tatgtacgtg tagttatgta   7380

taattttgta attagttaca atggtaaaaa aaatcaaaat atataaaaag tgatttgtac   7440

agaactttat tttagctctt ttttaaaaat gatttgcatg gttagaaaac ggcgaggaca   7500

gccaggggag ggaagggcct ctagggaact ttgcactttc tatacctttg tactatgcac   7560

tgccctattg attctacacc caataatgat attacttgaa cccatctgta agaaactgct   7620

tcggaaattc atttgtgtgt atgtaaataa cacaacatag aaacaggaag ggaaaaaagt   7680

ctgcagtaat gcacgtattt tttttctttc ctgtttattt tcggttttgc tttaagtcct   7740

tttattttta attccctttt tgtttttctt tttgggtttt ggttcctttt gggtttatgg   7800

gtgccctgat actccagcag agatcagaag gctacagatc cattctatcc atccgttatg   7860

tggctttgcc atcccagctt ggagtgtctt tacaaagata ataacagttg tgttctttgc   7920

tctcgttttg gatgcataga ctgaaaaatt aaaacaaata acttgtaaaa tggcttgtta   7980

aaaaatacaa ttacctctaa ttagtagtac gcgtaaatgt tttacagaat gaaaggcgtg   8040

ctttttattt tcttacttcg ttacattggt ggcgaaagaa gtctgtatga aaatcagttc   8100

tttgctgaca caagttccat ttgttacaaa tgaattctaa taaaaatgtc agtgttatgc   8160

a                                                                   8161


<210>  6015
<211>  1254
<212>  PRT
<213>  Homo sapiens

<400>  6015

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Met Phe Ala Lys Asn Phe His Val 
        355                 360                 365


Lys Ala Val Met Lys Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu 
    370                 375                 380


Asn Tyr Asn Ser Ala Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys 
385                 390                 395                 400


Met Val Glu Glu Val Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn 
                405                 410                 415


Leu Lys Pro Glu Lys Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn 
            420                 425                 430


Ser Ala Gly Gly Leu Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp 
        435                 440                 445


Val Leu Arg Thr Lys Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly 
    450                 455                 460


Met Ile Thr Val Gln Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys 
465                 470                 475                 480


Gly Tyr Tyr Ile Ile Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe 
                485                 490                 495


Ile Lys Pro Trp Glu Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu 
            500                 505                 510


Lys Glu Ile Ser Arg Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val 
        515                 520                 525


Glu Leu Lys Pro Tyr Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu 
    530                 535                 540


Phe Thr Leu Gly Asp Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln 
545                 550                 555                 560


Leu Gln Ser Gly Gln Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu 
                565                 570                 575


His Ala Glu Ser Lys Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val 
            580                 585                 590


Val Ser Met Asp Leu Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly 
        595                 600                 605


Leu Ile Trp Val Val Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys 
    610                 615                 620


Ile Val Ile Ala Ile Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp 
625                 630                 635                 640


Ser Arg Lys Ser Ser Ile Pro Asn Asn Lys Glu Ile Pro Ser His His 
                645                 650                 655


Pro Thr Asp Pro Val Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly 
            660                 665                 670


Met Ala Ser His Pro Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile 
        675                 680                 685


Glu Arg Leu Lys Ala Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu 
    690                 695                 700


Ser Ile Asp Pro Gly Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu 
705                 710                 715                 720


Val Asn Lys Pro Lys Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His 
                725                 730                 735


Ser Arg Val Leu Leu Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr 
            740                 745                 750


Val Asn Ala Asn Tyr Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile 
        755                 760                 765


Ala Thr Gln Gly Ser Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met 
    770                 775                 780


Ile Trp Glu Gln Arg Ser Ala Thr Val Val Met Met Thr Lys Leu Glu 
785                 790                 795                 800


Glu Arg Ser Arg Val Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr 
                805                 810                 815


Glu Thr His Gly Leu Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu 
            820                 825                 830


Ala Thr Tyr Cys Val Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser 
        835                 840                 845


Glu Lys Arg Glu Val Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His 
    850                 855                 860


Gly Val Pro Glu His Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val 
865                 870                 875                 880


Lys Thr Cys Asn Pro Pro Asp Ala Gly Pro Met Val Val His Cys Ser 
                885                 890                 895


Ala Gly Val Gly Arg Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu 
            900                 905                 910


Glu Arg Ile Lys His Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr 
        915                 920                 925


Leu Met Arg Ala Gln Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr 
    930                 935                 940


Ile Phe Ile His Asp Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr 
945                 950                 955                 960


Glu Val Pro Ala Arg Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln 
                965                 970                 975


Ile Glu Thr Gly Glu Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg 
            980                 985                 990


Leu Ala Ser Ser Lys Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu 
        995                 1000                1005


Pro Cys Asn Lys Phe Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu 
    1010                1015                1020


Ser Thr Arg Val Cys Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp 
1025                1030                1035                1040


Tyr Ile Asn Ala Ser Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr 
                1045                1050                1055


Ile Ala Thr Gln Gly Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg 
            1060                1065                1070


Met Leu Trp Glu His Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu 
        1075                1080                1085


Arg Glu Met Gly Arg Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg 
    1090                1095                1100


Ser Ala Arg Tyr Gln Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn 
1105                1110                1115                1120


Met Pro Gln Tyr Ile Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp 
                1125                1130                1135


Gly Gln Ser Arg Thr Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu 
            1140                1145                1150


Gln Gly Val Pro Lys Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln 
        1155                1160                1165


Val His Lys Thr Lys Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val 
    1170                1175                1180


His Cys Ser Ala Gly Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser 
1185                1190                1195                1200


Ile Val Leu Glu Arg Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln 
                1205                1210                1215


Thr Val Lys Met Leu Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu 
            1220                1225                1230


Asp Gln Tyr Gln Phe Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser 
        1235                1240                1245


Phe Asp His Tyr Ala Thr 
    1250


<210>  6016
<211>  6172
<212>  DNA
<213>  Homo sapiens

<400>  6016
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aatgtttgca aaaaattttc   2100

atgtcaaagc agtaatgaag acttccgtgt tgctgtcttg ggagattcca gagaattata   2160

actccgccat gcctttcaaa attctttatg atgatgggaa aatggtagaa gaagtggatg   2220

gccgagccac acagaagtta attgtcaacc tgaagcctga gaaatcatat tcatttgtgc   2280

tgacaaatcg tggaaacagt gctggtgggc tgcagcacag ggtcacggca aagactgcac   2340

cagatgtatt acgtaccaag cctgccttca ttgggaagac caacttggat ggcatgatta   2400

ctgtgcaact gcctgaagta cctgcaaatg agaatataaa aggttactac ataataattg   2460

tgcctttgaa gaaatctcgc gggaaattta tcaagccatg ggagagtcca gatgaaatgg   2520

aattagatga gctgcttaag gagatatcta ggaagcgcag aagcatccgt tatgggagag   2580

aagttgaatt aaagccatat attgccgctc actttgatgt ccttcccact gagttcaccc   2640

tgggggatga caagcattat ggtggattta caaacaagca actccaaagt ggtcaagaat   2700

atgtcttctt tgtgttagca gtaatggaac atgcagagtc taagatgtat gcaaccagcc   2760

cttactccga ccccgtggtg tcaatggatc tggatccgca gccaatcacg gatgaagaag   2820

aaggcttgat ctgggttgta ggtcctgtcc ttgcagtggt ctttatcatc tgcattgtca   2880

ttgctattct tctttataaa aggaagaggg cagagtccga ctctagaaaa agcagcatac   2940

cgaacaataa ggagatccct tcacaccacc caacagaccc tgtagaactg aggcgcctta   3000

actttcaaac accgggtatg gctagccatc ctccaatacc catcttggaa cttgcagacc   3060

acattgaaag attgaaagca aatgacaact tgaagttttc ccaggaatat gagtcaattg   3120

accctggcca gcagttcact tgggaacatt caaacttgga agtaaacaaa ccaaagaata   3180

gatacgcgaa tgtaatcgca tatgatcatt cccgggttct cctatcagct atagaaggga   3240

tcccaggaag tgactatgtg aatgccaact acatagatgg gtataggaag caaaatgcct   3300

atattgcaac acagggatct ctccccgaaa catttgggga cttttggaga atgatatggg   3360

aacaacggag tgccacagtt gtcatgatga caaaactaga agaaagatca agggtgaagt   3420

gtgaccagta ttggcctagc agaggcacag aaacccacgg actcgttcaa gtaacgctgc   3480

ttgatactgt ggagctggcc acatattgtg ttcgaacatt tgcactttac aagaatggtt   3540

caagtgagaa gagagaagtg agacaattcc agttcaccgc ctggcctgat catggtgttc   3600

cagaacaccc tacacctttt ctagctttct tacgtagagt caaaacctgt aaccctcccg   3660

atgctggtcc gatggttgtg cactgcagtg cgggagttgg ccggactggt tgcttcatcg   3720

tcatagatgc catgttagaa agaataaagc atgaaaaaac tgtagatatt tatggccatg   3780

taactttaat gagagcccag aggaactata tggttcaaac agaagaccaa tacatcttta   3840

tccatgatgc actgttagaa gcagtgactt gtggaaatac cgaagtgcca gctagaaact   3900

tgtatgccta cattcagaag ctgacacaaa tagaaacggg agagaatgtc acaggaatgg   3960

agctcgaatt taagcgtcta gccagctcaa aagctcacac ctcaaggttt atcagtgcca   4020

atcttccatg taataaattc aaaaatcgcc ttgttaatat tatgccatat gaatccacaa   4080

gggtatgcct gcagcctatc cgtggagtag aaggatctga ttacatcaat gccagtttta   4140

ttgatggata cagacaacag aaagcctaca tcgctaccca ggggcccttg gcagagacca   4200

ctgaagactt ctggcggatg ctctgggaac acaattccac catagttgtg atgctcacca   4260

agctgcgtga aatgggcaga gagaaatgtc accaatactg gccagcagaa cggtctgcaa   4320

gataccagta ctttgttgta gatcccatgg ctgagtacaa catgccacag tatatcctaa   4380

gggaattcaa ggtcacagat gccagggacg gccagtcccg aacagtaagg cagttccagt   4440

tcactgactg gccagagcaa ggagtgccaa agtccggaga aggatttatt gacttcatcg   4500

gccaagtcca taaaacaaaa gaacagtttg gccaagatgg acccatttca gtccattgca   4560

gcgcgggcgt tggaagaact ggagtcttca taacgctaag cattgttttg gaaagaatga   4620

gatatgaagg agttgtagat atcttccaga ctgtcaaaat gttaagaaca caacgaccag   4680

ctatggtaca gacagaggat caatatcagt tttcctatcg tgccgcacta gagtacctgg   4740

gcagctttga ccactatgca acgtagaaac ccctgaccca ttctggattt ttactacagg   4800

cccttcaata tccatggagt ctcttctgag ccatacaggg cacttgagaa gtccttctta   4860

acttctagct aacaactact tagtgggact attacacaca aaacaaatta aaaacaaatt   4920

attccaggtg gaccaagaat ctgctttgac atcgcccctt cccaccatac tgctcataat   4980

aacattttag ggggaaaggg gagggaatgt ttaaaaagaa agtccttgat ttagtttttt   5040

agtattgtaa agatactgct gacctgtgct tcatttctaa ctgtgtaaac ttttttttaa   5100

caaaatgtat cattcgataa agtgaatttt aaaaaagtta cataactctt cattttttta   5160

tttccaaatc gtaggttttt ttaagctgta gaactgttat ctgtaatatc ttgctgtaga   5220

aatatcaaat catttgaaaa tttgcacatt tttgtgcaaa actcaatcta cagtatcagt   5280

ctcgtcagat atattaattt tacacttcag ttttgattgg tgagaaagta cccattctct   5340

tcaaataatc aaagataatt attattttgt tttgtttttg gaatcaacag ggaggcgcaa   5400

agtataaagt tgctgctaac atatatacat atatatccat attttataag ggtgtctatg   5460

tatatataga cagtgtgtcc acacaaaaaa tagatacagt tatcagtcag tcagttcttc   5520

catgatttag tttttttaaa cgtagaaaag ctattgtaaa catctctttc catttattct   5580

taattttttg acatattggt atttctttaa agggaaatga ggaatgcaca tcagtgattg   5640

attgtcaaac ctcaccccct gatttcctac ctaatctacc cccacctaac caatcaatca   5700

catccacaaa ttgttttgtt tgtttgttag tcaggcttcc aacaaagttc aatatttcta   5760

acactctagt gcaataaaaa ttattattaa atagctaaga ggtgtgcatg tgggaaaggt   5820

cagtgcatat ccctttagga ggggagaatg ttgtaatata tcagctatcg agttgtttaa   5880

aaaaagtgta ttcaatcgta tattgtctat agtatgtgct atgaaatttg catttatgat   5940

atgtaacagg ggcaaagcca aattcatgtt actctgttca gtcagaaaca ttttgtggca   6000

tacagcattc ctgggaagtg ctgtactttg tttcgttttg gttttagttt tgcatttaga   6060

gtgccttata attgatgcct attttaatag catttctttt tagcttttgg ttcgtatttc   6120

cattcactgt tcgtatctgt tactttctat taaagcatta tctgtttacc ac           6172


<210>  6017
<211>  1254
<212>  PRT
<213>  Homo sapiens

<400>  6017

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Met Phe Ala Lys Asn Phe His Val 
        355                 360                 365


Lys Ala Val Met Lys Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu 
    370                 375                 380


Asn Tyr Asn Ser Ala Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys 
385                 390                 395                 400


Met Val Glu Glu Val Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn 
                405                 410                 415


Leu Lys Pro Glu Lys Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn 
            420                 425                 430


Ser Ala Gly Gly Leu Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp 
        435                 440                 445


Val Leu Arg Thr Lys Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly 
    450                 455                 460


Met Ile Thr Val Gln Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys 
465                 470                 475                 480


Gly Tyr Tyr Ile Ile Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe 
                485                 490                 495


Ile Lys Pro Trp Glu Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu 
            500                 505                 510


Lys Glu Ile Ser Arg Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val 
        515                 520                 525


Glu Leu Lys Pro Tyr Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu 
    530                 535                 540


Phe Thr Leu Gly Asp Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln 
545                 550                 555                 560


Leu Gln Ser Gly Gln Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu 
                565                 570                 575


His Ala Glu Ser Lys Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val 
            580                 585                 590


Val Ser Met Asp Leu Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly 
        595                 600                 605


Leu Ile Trp Val Val Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys 
    610                 615                 620


Ile Val Ile Ala Ile Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp 
625                 630                 635                 640


Ser Arg Lys Ser Ser Ile Pro Asn Asn Lys Glu Ile Pro Ser His His 
                645                 650                 655


Pro Thr Asp Pro Val Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly 
            660                 665                 670


Met Ala Ser His Pro Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile 
        675                 680                 685


Glu Arg Leu Lys Ala Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu 
    690                 695                 700


Ser Ile Asp Pro Gly Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu 
705                 710                 715                 720


Val Asn Lys Pro Lys Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His 
                725                 730                 735


Ser Arg Val Leu Leu Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr 
            740                 745                 750


Val Asn Ala Asn Tyr Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile 
        755                 760                 765


Ala Thr Gln Gly Ser Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met 
    770                 775                 780


Ile Trp Glu Gln Arg Ser Ala Thr Val Val Met Met Thr Lys Leu Glu 
785                 790                 795                 800


Glu Arg Ser Arg Val Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr 
                805                 810                 815


Glu Thr His Gly Leu Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu 
            820                 825                 830


Ala Thr Tyr Cys Val Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser 
        835                 840                 845


Glu Lys Arg Glu Val Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His 
    850                 855                 860


Gly Val Pro Glu His Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val 
865                 870                 875                 880


Lys Thr Cys Asn Pro Pro Asp Ala Gly Pro Met Val Val His Cys Ser 
                885                 890                 895


Ala Gly Val Gly Arg Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu 
            900                 905                 910


Glu Arg Ile Lys His Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr 
        915                 920                 925


Leu Met Arg Ala Gln Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr 
    930                 935                 940


Ile Phe Ile His Asp Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr 
945                 950                 955                 960


Glu Val Pro Ala Arg Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln 
                965                 970                 975


Ile Glu Thr Gly Glu Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg 
            980                 985                 990


Leu Ala Ser Ser Lys Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu 
        995                 1000                1005


Pro Cys Asn Lys Phe Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu 
    1010                1015                1020


Ser Thr Arg Val Cys Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp 
1025                1030                1035                1040


Tyr Ile Asn Ala Ser Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr 
                1045                1050                1055


Ile Ala Thr Gln Gly Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg 
            1060                1065                1070


Met Leu Trp Glu His Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu 
        1075                1080                1085


Arg Glu Met Gly Arg Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg 
    1090                1095                1100


Ser Ala Arg Tyr Gln Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn 
1105                1110                1115                1120


Met Pro Gln Tyr Ile Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp 
                1125                1130                1135


Gly Gln Ser Arg Thr Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu 
            1140                1145                1150


Gln Gly Val Pro Lys Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln 
        1155                1160                1165


Val His Lys Thr Lys Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val 
    1170                1175                1180


His Cys Ser Ala Gly Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser 
1185                1190                1195                1200


Ile Val Leu Glu Arg Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln 
                1205                1210                1215


Thr Val Lys Met Leu Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu 
            1220                1225                1230


Asp Gln Tyr Gln Phe Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser 
        1235                1240                1245


Phe Asp His Tyr Ala Thr 
    1250


<210>  6018
<211>  7393
<212>  DNA
<213>  Homo sapiens

<400>  6018
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcagt tcgccgtgtc ccaccaagat    960

tctctatccc acccactaat catgaaatca tgccaggcgg aagcgttaat atcacctgtg   1020

tggccgtggg gtcaccaatg ccttatgtaa agtggatgtt gggggcagaa gatctgacac   1080

ctgaagatga tatgccaata ggaagaaatg tgctagaact gaatgatgta agacagtcag   1140

caaattacac ctgtgttgct atgtcaacac tgggtgtcat tgaagcaata gcacagatca   1200

ctgtcaaagc cttacccaaa cctccaggaa ctcctgtagt gaccgagagc acagctacaa   1260

gcatcacact gacgtgggac tctgggaacc ctgagcctgt ttcttattac ataattcagc   1320

ataaacctaa aaactctgag gaactttaca aagaaattga tggggtggcg accacacgct   1380

acagtgtcgc tggactaagt ccctactcgg attatgaatt cagggttgtt gctgtcaata   1440

acattgggcg ggggcctccc agcgaacctg tgctaacaca aacctcagag caagcaccat   1500

ccagtgcccc gagggatgtc caggcacgaa tgttgagttc gaccaccatt ttggtacagt   1560

ggaaggaacc tgaagagcca aatggacaga tccaaggata tagagtttat tatacaatgg   1620

atcccactca acatgtcaac aactggatga aacacaatgt agctgacagc caaatcacta   1680

ctattggcaa cttagtgccc cagaaaacat attctgtcaa agtcctggct tttacctcaa   1740

ttggagatgg tcccctttca agtgacatac aagtcatcac tcagacagga gtaccagggc   1800

agccactaaa cttcaaagca gaacctgagt ctgaaacaag tattttgctc tcttggacac   1860

ctccacgttc agataccatt gccaactatg aactggtcta caaagatggg gagcatggag   1920

aggagcaacg aattaccatt gagccaggga catcatatag gctgcaagga ctgaaaccaa   1980

acagcttata ctatttccgt ctggctgcac gctcccctca aggcctgggt gcttctactg   2040

cagaaatatc agctagaacc atgcagtcaa agccgtcagc tcctcctcaa gacattagtt   2100

gcaccagccc aagttccact agtattttgg taagttggca acctccacca gtggaaaaac   2160

agaatggcat tatcactgaa tactccatca agtacactgc agtggatggg gaagatgaca   2220

agcctcacga gattttggga attccttcgg acactaccaa ataccttttg gaacagctgg   2280

aaaaatggac tgaataccgg atcactgtga cagcccatac agatgtcggc cctggccctg   2340

agagcttgtc cgtgttgatt cgaaccaatg aagatgttcc tagtggtcct cctcgcaaag   2400

tcgaggtaga ggctgtcaac tcaacatctg ttaaagtctc atggcgctca cccgtgccca   2460

ataaacagca tggccagata agaggatatc aggtgcatta tgtgaggatg gaaaatggtg   2520

agcccaaggg ccagcccatg ctgaaagatg tcatgctggc tgatgcacag tgggaatttg   2580

atgatactac tgaacatgac atgatcattt ctgggctcca gcctgaaact tcctactccc   2640

tcaccgtcac agcctacaca accaaaggag atggtgctcg cagcaagccc aaactggtgt   2700

ccaccactgg ggcagttcca gggaaacctc ggcttgtgat taaccacact cagatgaata   2760

ctgctcttat tcagtggcac cctccggtgg acacatttgg acctcttcag ggctaccgtc   2820

taaaatttgg ccgcaaggat atggagccac ttactactct tgagttctct gaaaaagaag   2880

atcactttac agctacagac atccacaagg gagcatcata cgtcttcagg ctctcagcca   2940

gaaacaaagt gggctttggg gaggagatgg tgaaggagat ttccattcca gaagaagtac   3000

caactggatt ccctcaaaac cttcactcag aaggcaccac ttcaacctcc gtccagttat   3060

cttggcaacc acctgtcctg gcagagagaa atggcattat caccaagtat acccttcttt   3120

atagggatat caacatcccc cttctcccga tggagcagct tattgttcca gctgacacca   3180

ctatgacact cactggctta aaaccagata ccacatacga tgtaaaagta cgtgctcata   3240

cgagcaaagg gcccgggcca tatagtccca gtgtccagtt caggacactg cctgtggatc   3300

aagtgtttgc aaaaaatttt catgtcaaag cagtaatgaa gacttccgtg ttgctgtctt   3360

gggagattcc agagaattat aactccgcca tgcctttcaa aattctttat gatgatggga   3420

aaatggtaga agaagtggat ggccgagcca cacagaagtt aattgtcaac ctgaagcctg   3480

agaaatcata ttcatttgtg ctgacaaatc gtggaaacag tgctggtggg ctgcagcaca   3540

gggtcacggc aaagactgca ccagatgtat tacgtaccaa gcctgccttc attgggaaga   3600

ccaacttgga tggcatgatt actgtgcaac tgcctgaagt acctgcaaat gagaatataa   3660

aaggttacta cataataatt gtgcctttga agaaatctcg cgggaaattt atcaagccat   3720

gggagagtcc agatgaaatg gaattagatg agctgcttaa ggagatatct aggaagcgca   3780

gaagcatccg ttatgggaga gaagttgaat taaagccata tattgccgct cactttgatg   3840

tccttcccac tgagttcacc ctgggggatg acaagcatta tggtggattt acaaacaagc   3900

aactccaaag tggtcaagaa tatgtcttct ttgtgttagc agtaatggaa catgcagagt   3960

ctaagatgta tgcaaccagc ccttactccg accccgtggt gtcaatggat ctggatccgc   4020

agccaatcac ggatgaagaa gaaggcttga tctgggttgt aggtcctgtc cttgcagtgg   4080

tctttatcat ctgcattgtc attgctattc ttctttataa aaggaagagg gcagagtccg   4140

actctagaaa aagcagcata ccgaacaata aggagatccc ttcacaccac ccaacagacc   4200

ctgtagaact gaggcgcctt aactttcaaa caccgggtat ggctagccat cctccaatac   4260

ccatcttgga acttgcagac cacattgaaa gattgaaagc aaatgacaac ttgaagtttt   4320

cccaggaata tgagtcaatt gaccctggcc agcagttcac ttgggaacat tcaaacttgg   4380

aagtaaacaa accaaagaat agatacgcga atgtaatcgc atatgatcat tcccgggttc   4440

tcctatcagc tatagaaggg atcccaggaa gtgactatgt gaatgccaac tacatagatg   4500

ggtataggaa gcaaaatgcc tatattgcaa cacagggatc tctccccgaa acatttgggg   4560

acttttggag aatgatatgg gaacaacgga gtgccacagt tgtcatgatg acaaaactag   4620

aagaaagatc aagggtgaag tgtgaccagt attggcctag cagaggcaca gaaacccacg   4680

gactcgttca agtaacgctg cttgatactg tggagctggc cacatattgt gttcgaacat   4740

ttgcacttta caagaatggt tcaagtgaga agagagaagt gagacaattc cagttcaccg   4800

cctggcctga tcatggtgtt ccagaacacc ctacaccttt tctagctttc ttacgtagag   4860

tcaaaacctg taaccctccc gatgctggtc cgatggttgt gcactgcagt gcgggagttg   4920

gccggactgg ttgcttcatc gtcatagatg ccatgttaga aagaataaag catgaaaaaa   4980

ctgtagatat ttatggccat gtaactttaa tgagagccca gaggaactat atggttcaaa   5040

cagaagacca atacatcttt atccatgatg cactgttaga agcagtgact tgtggaaata   5100

ccgaagtgcc agctagaaac ttgtatgcct acattcagaa gctgacacaa atagaaacgg   5160

gagagaatgt cacaggaatg gagctcgaat ttaagcgtct agccagctca aaagctcaca   5220

cctcaaggtt tatcagtgcc aatcttccat gtaataaatt caaaaatcgc cttgttaata   5280

ttatgccata tgaatccaca agggtatgcc tgcagcctat ccgtggagta gaaggatctg   5340

attacatcaa tgccagtttt attgatggat acagacaaca gaaagcctac atcgctaccc   5400

aggggccctt ggcagagacc actgaagact tctggcggat gctctgggaa cacaattcca   5460

ccatagttgt gatgctcacc aagctgcgtg aaatgggcag agagaaatgt caccaatact   5520

ggccagcaga acggtctgca agataccagt actttgttgt agatcccatg gctgagtaca   5580

acatgccaca gtatatccta agggaattca aggtcacaga tgccagggac ggccagtccc   5640

gaacagtaag gcagttccag ttcactgact ggccagagca aggagtgcca aagtccggag   5700

aaggatttat tgacttcatc ggccaagtcc ataaaacaaa agaacagttt ggccaagatg   5760

gacccatttc agtccattgc agcgcgggcg ttggaagaac tggagtcttc ataacgctaa   5820

gcattgtttt ggaaagaatg agatatgaag gagttgtaga tatcttccag actgtcaaaa   5880

tgttaagaac acaacgacca gctatggtac agacagagga tcaatatcag ttttcctatc   5940

gtgccgcact agagtacctg ggcagctttg accactatgc aacgtagaaa cccctgaccc   6000

attctggatt tttactacag gcccttcaat atccatggag tctcttctga gccatacagg   6060

gcacttgaga agtccttctt aacttctagc taacaactac ttagtgggac tattacacac   6120

aaaacaaatt aaaaacaaat tattccaggt ggaccaagaa tctgctttga catcgcccct   6180

tcccaccata ctgctcataa taacatttta gggggaaagg ggagggaatg tttaaaaaga   6240

aagtccttga tttagttttt tagtattgta aagatactgc tgacctgtgc ttcatttcta   6300

actgtgtaaa ctttttttta acaaaatgta tcattcgata aagtgaattt taaaaaagtt   6360

acataactct tcattttttt atttccaaat cgtaggtttt tttaagctgt agaactgtta   6420

tctgtaatat cttgctgtag aaatatcaaa tcatttgaaa atttgcacat ttttgtgcaa   6480

aactcaatct acagtatcag tctcgtcaga tatattaatt ttacacttca gttttgattg   6540

gtgagaaagt acccattctc ttcaaataat caaagataat tattattttg ttttgttttt   6600

ggaatcaaca gggaggcgca aagtataaag ttgctgctaa catatataca tatatatcca   6660

tattttataa gggtgtctat gtatatatag acagtgtgtc cacacaaaaa atagatacag   6720

ttatcagtca gtcagttctt ccatgattta gtttttttaa acgtagaaaa gctattgtaa   6780

acatctcttt ccatttattc ttaatttttt gacatattgg tatttcttta aagggaaatg   6840

aggaatgcac atcagtgatt gattgtcaaa cctcaccccc tgatttccta cctaatctac   6900

ccccacctaa ccaatcaatc acatccacaa attgttttgt ttgtttgtta gtcaggcttc   6960

caacaaagtt caatatttct aacactctag tgcaataaaa attattatta aatagctaag   7020

aggtgtgcat gtgggaaagg tcagtgcata tccctttagg aggggagaat gttgtaatat   7080

atcagctatc gagttgttta aaaaaagtgt attcaatcgt atattgtcta tagtatgtgc   7140

tatgaaattt gcatttatga tatgtaacag gggcaaagcc aaattcatgt tactctgttc   7200

agtcagaaac attttgtggc atacagcatt cctgggaagt gctgtacttt gtttcgtttt   7260

ggttttagtt ttgcatttag agtgccttat aattgatgcc tattttaata gcatttcttt   7320

ttagcttttg gttcgtattt ccattcactg ttcgtatctg ttactttcta ttaaagcatt   7380

atctgtttac cac                                                      7393


<210>  6019
<211>  1665
<212>  PRT
<213>  Homo sapiens

<400>  6019

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Trp 
        515                 520                 525


Glu Phe Asp Asp Thr Thr Glu His Asp Met Ile Ile Ser Gly Leu Gln 
    530                 535                 540


Pro Glu Thr Ser Tyr Ser Leu Thr Val Thr Ala Tyr Thr Thr Lys Gly 
545                 550                 555                 560


Asp Gly Ala Arg Ser Lys Pro Lys Leu Val Ser Thr Thr Gly Ala Val 
                565                 570                 575


Pro Gly Lys Pro Arg Leu Val Ile Asn His Thr Gln Met Asn Thr Ala 
            580                 585                 590


Leu Ile Gln Trp His Pro Pro Val Asp Thr Phe Gly Pro Leu Gln Gly 
        595                 600                 605


Tyr Arg Leu Lys Phe Gly Arg Lys Asp Met Glu Pro Leu Thr Thr Leu 
    610                 615                 620


Glu Phe Ser Glu Lys Glu Asp His Phe Thr Ala Thr Asp Ile His Lys 
625                 630                 635                 640


Gly Ala Ser Tyr Val Phe Arg Leu Ser Ala Arg Asn Lys Val Gly Phe 
                645                 650                 655


Gly Glu Glu Met Val Lys Glu Ile Ser Ile Pro Glu Glu Val Pro Thr 
            660                 665                 670


Gly Phe Pro Gln Asn Leu His Ser Glu Gly Thr Thr Ser Thr Ser Val 
        675                 680                 685


Gln Leu Ser Trp Gln Pro Pro Val Leu Ala Glu Arg Asn Gly Ile Ile 
    690                 695                 700


Thr Lys Tyr Thr Leu Leu Tyr Arg Asp Ile Asn Ile Pro Leu Leu Pro 
705                 710                 715                 720


Met Glu Gln Leu Ile Val Pro Ala Asp Thr Thr Met Thr Leu Thr Gly 
                725                 730                 735


Leu Lys Pro Asp Thr Thr Tyr Asp Val Lys Val Arg Ala His Thr Ser 
            740                 745                 750


Lys Gly Pro Gly Pro Tyr Ser Pro Ser Val Gln Phe Arg Thr Leu Pro 
        755                 760                 765


Val Asp Gln Val Phe Ala Lys Asn Phe His Val Lys Ala Val Met Lys 
    770                 775                 780


Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu Asn Tyr Asn Ser Ala 
785                 790                 795                 800


Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys Met Val Glu Glu Val 
                805                 810                 815


Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn Leu Lys Pro Glu Lys 
            820                 825                 830


Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn Ser Ala Gly Gly Leu 
        835                 840                 845


Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp Val Leu Arg Thr Lys 
    850                 855                 860


Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly Met Ile Thr Val Gln 
865                 870                 875                 880


Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys Gly Tyr Tyr Ile Ile 
                885                 890                 895


Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe Ile Lys Pro Trp Glu 
            900                 905                 910


Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu Lys Glu Ile Ser Arg 
        915                 920                 925


Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val Glu Leu Lys Pro Tyr 
    930                 935                 940


Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu Phe Thr Leu Gly Asp 
945                 950                 955                 960


Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln Leu Gln Ser Gly Gln 
                965                 970                 975


Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu His Ala Glu Ser Lys 
            980                 985                 990


Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val Val Ser Met Asp Leu 
        995                 1000                1005


Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly Leu Ile Trp Val Val 
    1010                1015                1020


Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys Ile Val Ile Ala Ile 
1025                1030                1035                1040


Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp Ser Arg Lys Ser Ser 
                1045                1050                1055


Ile Pro Asn Asn Lys Glu Ile Pro Ser His His Pro Thr Asp Pro Val 
            1060                1065                1070


Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly Met Ala Ser His Pro 
        1075                1080                1085


Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile Glu Arg Leu Lys Ala 
    1090                1095                1100


Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu Ser Ile Asp Pro Gly 
1105                1110                1115                1120


Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu Val Asn Lys Pro Lys 
                1125                1130                1135


Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His Ser Arg Val Leu Leu 
            1140                1145                1150


Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr Val Asn Ala Asn Tyr 
        1155                1160                1165


Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile Ala Thr Gln Gly Ser 
    1170                1175                1180


Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met Ile Trp Glu Gln Arg 
1185                1190                1195                1200


Ser Ala Thr Val Val Met Met Thr Lys Leu Glu Glu Arg Ser Arg Val 
                1205                1210                1215


Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr Glu Thr His Gly Leu 
            1220                1225                1230


Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu Ala Thr Tyr Cys Val 
        1235                1240                1245


Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser Glu Lys Arg Glu Val 
    1250                1255                1260


Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His Gly Val Pro Glu His 
1265                1270                1275                1280


Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val Lys Thr Cys Asn Pro 
                1285                1290                1295


Pro Asp Ala Gly Pro Met Val Val His Cys Ser Ala Gly Val Gly Arg 
            1300                1305                1310


Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu Glu Arg Ile Lys His 
        1315                1320                1325


Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr Leu Met Arg Ala Gln 
    1330                1335                1340


Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr Ile Phe Ile His Asp 
1345                1350                1355                1360


Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr Glu Val Pro Ala Arg 
                1365                1370                1375


Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln Ile Glu Thr Gly Glu 
            1380                1385                1390


Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg Leu Ala Ser Ser Lys 
        1395                1400                1405


Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu Pro Cys Asn Lys Phe 
    1410                1415                1420


Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu Ser Thr Arg Val Cys 
1425                1430                1435                1440


Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp Tyr Ile Asn Ala Ser 
                1445                1450                1455


Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr Ile Ala Thr Gln Gly 
            1460                1465                1470


Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg Met Leu Trp Glu His 
        1475                1480                1485


Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu Arg Glu Met Gly Arg 
    1490                1495                1500


Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg Ser Ala Arg Tyr Gln 
1505                1510                1515                1520


Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn Met Pro Gln Tyr Ile 
                1525                1530                1535


Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp Gly Gln Ser Arg Thr 
            1540                1545                1550


Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu Gln Gly Val Pro Lys 
        1555                1560                1565


Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln Val His Lys Thr Lys 
    1570                1575                1580


Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val His Cys Ser Ala Gly 
1585                1590                1595                1600


Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser Ile Val Leu Glu Arg 
                1605                1610                1615


Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln Thr Val Lys Met Leu 
            1620                1625                1630


Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu Asp Gln Tyr Gln Phe 
        1635                1640                1645


Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser Phe Asp His Tyr Ala 
    1650                1655                1660


Thr 
1665


<210>  6020
<211>  7405
<212>  DNA
<213>  Homo sapiens

<400>  6020
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aaagccgtca gctcctcctc   2100

aagacattag ttgcaccagc ccaagttcca ctagtatttt ggtaagttgg caacctccac   2160

cagtggaaaa acagaatggc attatcactg aatactccat caagtacact gcagtggatg   2220

gggaagatga caagcctcac gagattttgg gaattccttc ggacactacc aaataccttt   2280

tggaacagct ggaaaaatgg actgaatacc ggatcactgt gacagcccat acagatgtcg   2340

gccctggccc tgagagcttg tccgtgttga ttcgaaccaa tgaagatgtt cctagtggtc   2400

ctcctcgcaa agtcgaggta gaggctgtca actcaacatc tgttaaagtc tcatggcgct   2460

cacccgtgcc caataaacag catggccaga taagaggata tcaggtgcat tatgtgagga   2520

tggaaaatgg tgagcccaag ggccagccca tgctgaaaga tgtcatgctg gctgatgcac   2580

agtgggaatt tgatgatact actgaacatg acatgatcat ttctgggctc cagcctgaaa   2640

cttcctactc cctcaccgtc acagcctaca caaccaaagg agatggtgct cgcagcaagc   2700

ccaaactggt gtccaccact ggggcagttc cagggaaacc tcggcttgtg attaaccaca   2760

ctcagatgaa tactgctctt attcagtggc accctccggt ggacacattt ggacctcttc   2820

agggctaccg tctaaaattt ggccgcaagg atatggagcc acttactact cttgagttct   2880

ctgaaaaaga agatcacttt acagctacag acatccacaa gggagcatca tacgtcttca   2940

ggctctcagc cagaaacaaa gtgggctttg gggaggagat ggtgaaggag atttccattc   3000

cagaagaagt accaactgga ttccctcaaa accttcactc agaaggcacc acttcaacct   3060

ccgtccagtt atcttggcaa ccacctgtcc tggcagagag aaatggcatt atcaccaagt   3120

atacccttct ttatagggat atcaacatcc cccttctccc gatggagcag cttattgttc   3180

cagctgacac cactatgaca ctcactggct taaaaccaga taccacatac gatgtaaaag   3240

tacgtgctca tacgagcaaa gggcccgggc catatagtcc cagtgtccag ttcaggacac   3300

tgcctgtgga tcaagtgttt gcaaaaaatt ttcatgtcaa agcagtaatg aagacttccg   3360

tgttgctgtc ttgggagatt ccagagaatt ataactccgc catgcctttc aaaattcttt   3420

atgatgatgg gaaaatggta gaagaagtgg atggccgagc cacacagaag ttaattgtca   3480

acctgaagcc tgagaaatca tattcatttg tgctgacaaa tcgtggaaac agtgctggtg   3540

ggctgcagca cagggtcacg gcaaagactg caccagatgt attacgtacc aagcctgcct   3600

tcattgggaa gaccaacttg gatggcatga ttactgtgca actgcctgaa gtacctgcaa   3660

atgagaatat aaaaggttac tacataataa ttgtgccttt gaagaaatct cgcgggaaat   3720

ttatcaagcc atgggagagt ccagatgaaa tggaattaga tgagctgctt aaggagatat   3780

ctaggaagcg cagaagcatc cgttatggga gagaagttga attaaagcca tatattgccg   3840

ctcactttga tgtccttccc actgagttca ccctggggga tgacaagcat tatggtggat   3900

ttacaaacaa gcaactccaa agtggtcaag aatatgtctt ctttgtgtta gcagtaatgg   3960

aacatgcaga gtctaagatg tatgcaacca gcccttactc cgaccccgtg gtgtcaatgg   4020

atctggatcc gcagccaatc acggatgaag aagaaggctt gatctgggtt gtaggtcctg   4080

tccttgcagt ggtctttatc atctgcattg tcattgctat tcttctttat aaaaggaaga   4140

gggcagagtc cgactctaga aaaagcagca taccgaacaa taaggagatc ccttcacacc   4200

acccaacaga ccctgtagaa ctgaggcgcc ttaactttca aacaccgggt atggctagcc   4260

atcctccaat acccatcttg gaacttgcag accacattga aagattgaaa gcaaatgaca   4320

acttgaagtt ttcccaggaa tatgagtcaa ttgaccctgg ccagcagttc acttgggaac   4380

attcaaactt ggaagtaaac aaaccaaaga atagatacgc gaatgtaatc gcatatgatc   4440

attcccgggt tctcctatca gctatagaag ggatcccagg aagtgactat gtgaatgcca   4500

actacataga tgggtatagg aagcaaaatg cctatattgc aacacaggga tctctccccg   4560

aaacatttgg ggacttttgg agaatgatat gggaacaacg gagtgccaca gttgtcatga   4620

tgacaaaact agaagaaaga tcaagggtga agtgtgacca gtattggcct agcagaggca   4680

cagaaaccca cggactcgtt caagtaacgc tgcttgatac tgtggagctg gccacatatt   4740

gtgttcgaac atttgcactt tacaagaatg gttcaagtga gaagagagaa gtgagacaat   4800

tccagttcac cgcctggcct gatcatggtg ttccagaaca ccctacacct tttctagctt   4860

tcttacgtag agtcaaaacc tgtaaccctc ccgatgctgg tccgatggtt gtgcactgca   4920

gtgcgggagt tggccggact ggttgcttca tcgtcataga tgccatgtta gaaagaataa   4980

agcatgaaaa aactgtagat atttatggcc atgtaacttt aatgagagcc cagaggaact   5040

atatggttca aacagaagac caatacatct ttatccatga tgcactgtta gaagcagtga   5100

cttgtggaaa taccgaagtg ccagctagaa acttgtatgc ctacattcag aagctgacac   5160

aaatagaaac gggagagaat gtcacaggaa tggagctcga atttaagcgt ctagccagct   5220

caaaagctca cacctcaagg tttatcagtg ccaatcttcc atgtaataaa ttcaaaaatc   5280

gccttgttaa tattatgcca tatgaatcca caagggtatg cctgcagcct atccgtggag   5340

tagaaggatc tgattacatc aatgccagtt ttattgatgg atacagacaa cagaaagcct   5400

acatcgctac ccaggggccc ttggcagaga ccactgaaga cttctggcgg atgctctggg   5460

aacacaattc caccatagtt gtgatgctca ccaagctgcg tgaaatgggc agagagaaat   5520

gtcaccaata ctggccagca gaacggtctg caagatacca gtactttgtt gtagatccca   5580

tggctgagta caacatgcca cagtatatcc taagggaatt caaggtcaca gatgccaggg   5640

acggccagtc ccgaacagta aggcagttcc agttcactga ctggccagag caaggagtgc   5700

caaagtccgg agaaggattt attgacttca tcggccaagt ccataaaaca aaagaacagt   5760

ttggccaaga tggacccatt tcagtccatt gcagcgcggg cgttggaaga actggagtct   5820

tcataacgct aagcattgtt ttggaaagaa tgagatatga aggagttgta gatatcttcc   5880

agactgtcaa aatgttaaga acacaacgac cagctatggt acagacagag gatcaatatc   5940

agttttccta tcgtgccgca ctagagtacc tgggcagctt tgaccactat gcaacgtaga   6000

aacccctgac ccattctgga tttttactac aggcccttca atatccatgg agtctcttct   6060

gagccataca gggcacttga gaagtccttc ttaacttcta gctaacaact acttagtggg   6120

actattacac acaaaacaaa ttaaaaacaa attattccag gtggaccaag aatctgcttt   6180

gacatcgccc cttcccacca tactgctcat aataacattt tagggggaaa ggggagggaa   6240

tgtttaaaaa gaaagtcctt gatttagttt tttagtattg taaagatact gctgacctgt   6300

gcttcatttc taactgtgta aacttttttt taacaaaatg tatcattcga taaagtgaat   6360

tttaaaaaag ttacataact cttcattttt ttatttccaa atcgtaggtt tttttaagct   6420

gtagaactgt tatctgtaat atcttgctgt agaaatatca aatcatttga aaatttgcac   6480

atttttgtgc aaaactcaat ctacagtatc agtctcgtca gatatattaa ttttacactt   6540

cagttttgat tggtgagaaa gtacccattc tcttcaaata atcaaagata attattattt   6600

tgttttgttt ttggaatcaa cagggaggcg caaagtataa agttgctgct aacatatata   6660

catatatatc catattttat aagggtgtct atgtatatat agacagtgtg tccacacaaa   6720

aaatagatac agttatcagt cagtcagttc ttccatgatt tagttttttt aaacgtagaa   6780

aagctattgt aaacatctct ttccatttat tcttaatttt ttgacatatt ggtatttctt   6840

taaagggaaa tgaggaatgc acatcagtga ttgattgtca aacctcaccc cctgatttcc   6900

tacctaatct acccccacct aaccaatcaa tcacatccac aaattgtttt gtttgtttgt   6960

tagtcaggct tccaacaaag ttcaatattt ctaacactct agtgcaataa aaattattat   7020

taaatagcta agaggtgtgc atgtgggaaa ggtcagtgca tatcccttta ggaggggaga   7080

atgttgtaat atatcagcta tcgagttgtt taaaaaaagt gtattcaatc gtatattgtc   7140

tatagtatgt gctatgaaat ttgcatttat gatatgtaac aggggcaaag ccaaattcat   7200

gttactctgt tcagtcagaa acattttgtg gcatacagca ttcctgggaa gtgctgtact   7260

ttgtttcgtt ttggttttag ttttgcattt agagtgcctt ataattgatg cctattttaa   7320

tagcatttct ttttagcttt tggttcgtat ttccattcac tgttcgtatc tgttactttc   7380

tattaaagca ttatctgttt accac                                         7405


<210>  6021
<211>  1665
<212>  PRT
<213>  Homo sapiens

<400>  6021

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Trp 
        515                 520                 525


Glu Phe Asp Asp Thr Thr Glu His Asp Met Ile Ile Ser Gly Leu Gln 
    530                 535                 540


Pro Glu Thr Ser Tyr Ser Leu Thr Val Thr Ala Tyr Thr Thr Lys Gly 
545                 550                 555                 560


Asp Gly Ala Arg Ser Lys Pro Lys Leu Val Ser Thr Thr Gly Ala Val 
                565                 570                 575


Pro Gly Lys Pro Arg Leu Val Ile Asn His Thr Gln Met Asn Thr Ala 
            580                 585                 590


Leu Ile Gln Trp His Pro Pro Val Asp Thr Phe Gly Pro Leu Gln Gly 
        595                 600                 605


Tyr Arg Leu Lys Phe Gly Arg Lys Asp Met Glu Pro Leu Thr Thr Leu 
    610                 615                 620


Glu Phe Ser Glu Lys Glu Asp His Phe Thr Ala Thr Asp Ile His Lys 
625                 630                 635                 640


Gly Ala Ser Tyr Val Phe Arg Leu Ser Ala Arg Asn Lys Val Gly Phe 
                645                 650                 655


Gly Glu Glu Met Val Lys Glu Ile Ser Ile Pro Glu Glu Val Pro Thr 
            660                 665                 670


Gly Phe Pro Gln Asn Leu His Ser Glu Gly Thr Thr Ser Thr Ser Val 
        675                 680                 685


Gln Leu Ser Trp Gln Pro Pro Val Leu Ala Glu Arg Asn Gly Ile Ile 
    690                 695                 700


Thr Lys Tyr Thr Leu Leu Tyr Arg Asp Ile Asn Ile Pro Leu Leu Pro 
705                 710                 715                 720


Met Glu Gln Leu Ile Val Pro Ala Asp Thr Thr Met Thr Leu Thr Gly 
                725                 730                 735


Leu Lys Pro Asp Thr Thr Tyr Asp Val Lys Val Arg Ala His Thr Ser 
            740                 745                 750


Lys Gly Pro Gly Pro Tyr Ser Pro Ser Val Gln Phe Arg Thr Leu Pro 
        755                 760                 765


Val Asp Gln Val Phe Ala Lys Asn Phe His Val Lys Ala Val Met Lys 
    770                 775                 780


Thr Ser Val Leu Leu Ser Trp Glu Ile Pro Glu Asn Tyr Asn Ser Ala 
785                 790                 795                 800


Met Pro Phe Lys Ile Leu Tyr Asp Asp Gly Lys Met Val Glu Glu Val 
                805                 810                 815


Asp Gly Arg Ala Thr Gln Lys Leu Ile Val Asn Leu Lys Pro Glu Lys 
            820                 825                 830


Ser Tyr Ser Phe Val Leu Thr Asn Arg Gly Asn Ser Ala Gly Gly Leu 
        835                 840                 845


Gln His Arg Val Thr Ala Lys Thr Ala Pro Asp Val Leu Arg Thr Lys 
    850                 855                 860


Pro Ala Phe Ile Gly Lys Thr Asn Leu Asp Gly Met Ile Thr Val Gln 
865                 870                 875                 880


Leu Pro Glu Val Pro Ala Asn Glu Asn Ile Lys Gly Tyr Tyr Ile Ile 
                885                 890                 895


Ile Val Pro Leu Lys Lys Ser Arg Gly Lys Phe Ile Lys Pro Trp Glu 
            900                 905                 910


Ser Pro Asp Glu Met Glu Leu Asp Glu Leu Leu Lys Glu Ile Ser Arg 
        915                 920                 925


Lys Arg Arg Ser Ile Arg Tyr Gly Arg Glu Val Glu Leu Lys Pro Tyr 
    930                 935                 940


Ile Ala Ala His Phe Asp Val Leu Pro Thr Glu Phe Thr Leu Gly Asp 
945                 950                 955                 960


Asp Lys His Tyr Gly Gly Phe Thr Asn Lys Gln Leu Gln Ser Gly Gln 
                965                 970                 975


Glu Tyr Val Phe Phe Val Leu Ala Val Met Glu His Ala Glu Ser Lys 
            980                 985                 990


Met Tyr Ala Thr Ser Pro Tyr Ser Asp Pro Val Val Ser Met Asp Leu 
        995                 1000                1005


Asp Pro Gln Pro Ile Thr Asp Glu Glu Glu Gly Leu Ile Trp Val Val 
    1010                1015                1020


Gly Pro Val Leu Ala Val Val Phe Ile Ile Cys Ile Val Ile Ala Ile 
1025                1030                1035                1040


Leu Leu Tyr Lys Arg Lys Arg Ala Glu Ser Asp Ser Arg Lys Ser Ser 
                1045                1050                1055


Ile Pro Asn Asn Lys Glu Ile Pro Ser His His Pro Thr Asp Pro Val 
            1060                1065                1070


Glu Leu Arg Arg Leu Asn Phe Gln Thr Pro Gly Met Ala Ser His Pro 
        1075                1080                1085


Pro Ile Pro Ile Leu Glu Leu Ala Asp His Ile Glu Arg Leu Lys Ala 
    1090                1095                1100


Asn Asp Asn Leu Lys Phe Ser Gln Glu Tyr Glu Ser Ile Asp Pro Gly 
1105                1110                1115                1120


Gln Gln Phe Thr Trp Glu His Ser Asn Leu Glu Val Asn Lys Pro Lys 
                1125                1130                1135


Asn Arg Tyr Ala Asn Val Ile Ala Tyr Asp His Ser Arg Val Leu Leu 
            1140                1145                1150


Ser Ala Ile Glu Gly Ile Pro Gly Ser Asp Tyr Val Asn Ala Asn Tyr 
        1155                1160                1165


Ile Asp Gly Tyr Arg Lys Gln Asn Ala Tyr Ile Ala Thr Gln Gly Ser 
    1170                1175                1180


Leu Pro Glu Thr Phe Gly Asp Phe Trp Arg Met Ile Trp Glu Gln Arg 
1185                1190                1195                1200


Ser Ala Thr Val Val Met Met Thr Lys Leu Glu Glu Arg Ser Arg Val 
                1205                1210                1215


Lys Cys Asp Gln Tyr Trp Pro Ser Arg Gly Thr Glu Thr His Gly Leu 
            1220                1225                1230


Val Gln Val Thr Leu Leu Asp Thr Val Glu Leu Ala Thr Tyr Cys Val 
        1235                1240                1245


Arg Thr Phe Ala Leu Tyr Lys Asn Gly Ser Ser Glu Lys Arg Glu Val 
    1250                1255                1260


Arg Gln Phe Gln Phe Thr Ala Trp Pro Asp His Gly Val Pro Glu His 
1265                1270                1275                1280


Pro Thr Pro Phe Leu Ala Phe Leu Arg Arg Val Lys Thr Cys Asn Pro 
                1285                1290                1295


Pro Asp Ala Gly Pro Met Val Val His Cys Ser Ala Gly Val Gly Arg 
            1300                1305                1310


Thr Gly Cys Phe Ile Val Ile Asp Ala Met Leu Glu Arg Ile Lys His 
        1315                1320                1325


Glu Lys Thr Val Asp Ile Tyr Gly His Val Thr Leu Met Arg Ala Gln 
    1330                1335                1340


Arg Asn Tyr Met Val Gln Thr Glu Asp Gln Tyr Ile Phe Ile His Asp 
1345                1350                1355                1360


Ala Leu Leu Glu Ala Val Thr Cys Gly Asn Thr Glu Val Pro Ala Arg 
                1365                1370                1375


Asn Leu Tyr Ala Tyr Ile Gln Lys Leu Thr Gln Ile Glu Thr Gly Glu 
            1380                1385                1390


Asn Val Thr Gly Met Glu Leu Glu Phe Lys Arg Leu Ala Ser Ser Lys 
        1395                1400                1405


Ala His Thr Ser Arg Phe Ile Ser Ala Asn Leu Pro Cys Asn Lys Phe 
    1410                1415                1420


Lys Asn Arg Leu Val Asn Ile Met Pro Tyr Glu Ser Thr Arg Val Cys 
1425                1430                1435                1440


Leu Gln Pro Ile Arg Gly Val Glu Gly Ser Asp Tyr Ile Asn Ala Ser 
                1445                1450                1455


Phe Ile Asp Gly Tyr Arg Gln Gln Lys Ala Tyr Ile Ala Thr Gln Gly 
            1460                1465                1470


Pro Leu Ala Glu Thr Thr Glu Asp Phe Trp Arg Met Leu Trp Glu His 
        1475                1480                1485


Asn Ser Thr Ile Val Val Met Leu Thr Lys Leu Arg Glu Met Gly Arg 
    1490                1495                1500


Glu Lys Cys His Gln Tyr Trp Pro Ala Glu Arg Ser Ala Arg Tyr Gln 
1505                1510                1515                1520


Tyr Phe Val Val Asp Pro Met Ala Glu Tyr Asn Met Pro Gln Tyr Ile 
                1525                1530                1535


Leu Arg Glu Phe Lys Val Thr Asp Ala Arg Asp Gly Gln Ser Arg Thr 
            1540                1545                1550


Val Arg Gln Phe Gln Phe Thr Asp Trp Pro Glu Gln Gly Val Pro Lys 
        1555                1560                1565


Ser Gly Glu Gly Phe Ile Asp Phe Ile Gly Gln Val His Lys Thr Lys 
    1570                1575                1580


Glu Gln Phe Gly Gln Asp Gly Pro Ile Ser Val His Cys Ser Ala Gly 
1585                1590                1595                1600


Val Gly Arg Thr Gly Val Phe Ile Thr Leu Ser Ile Val Leu Glu Arg 
                1605                1610                1615


Met Arg Tyr Glu Gly Val Val Asp Ile Phe Gln Thr Val Lys Met Leu 
            1620                1625                1630


Arg Thr Gln Arg Pro Ala Met Val Gln Thr Glu Asp Gln Tyr Gln Phe 
        1635                1640                1645


Ser Tyr Arg Ala Ala Leu Glu Tyr Leu Gly Ser Phe Asp His Tyr Ala 
    1650                1655                1660


Thr 
1665


<210>  6022
<211>  7378
<212>  DNA
<213>  Homo sapiens

<400>  6022
tgagaccaca gcagaatgtg ccttggacaa aggtctcagg gtggtgaact ttttcttcga     60

attcctaacc tgtgagctta cgatgatggt gcctgtccat taactgaaca actgtggttt    120

tgaacttctt gaggccaggg actgtgtctg aaaacaccga cggtggctaa ctcaagggag    180

acgtctggtg aacacccgtg ggatctaaag aacaagctct gaaagtgttc cagctgaaat    240

ttcagatcgg acagactcgc tgcggctccg gaggcagtga ttccaagctg ctcgcgcacg    300

ctgctgccaa gctgcaggat ggtgcacgta gccaggctgc tgctgctgct cctcactttc    360

ttcctccgca cggatgctga gacacctcca aggtttacac gaacacccgt tgatcagaca    420

ggggtctctg gcggagttgc ctctttcatc tgccaagcta cgggagaccc aagacctaaa    480

attgtctgga acaaaaaagg aaagaaagtc agcaatcaga gatttgaggt aatagagttt    540

gacgatgggt ctggatcagt tctcagaata caacccttac ggactccgag ggatgaggcc    600

atttatgaat gtgtggcctc aaataatgtg ggagaaataa gtgtatccac cagactcaca    660

gttttgcggg aagatcaaat tcccaggggc ttccctacca ttgacatggg cccacagttg    720

aaggtggttg agcgtactcg cacggccacc atgctttgtg cagccagtgg taatccggat    780

ccagaaatca cttggtttaa agatttctta cctgtggaca caagcaacaa caatggtcgt    840

attaagcagt tacgatcagg agcccttcag attgagcaga gtgaagagtc tgaccaagga    900

aaatatgagt gtgttgccac caacagcgcg ggcactcaga gctgcgagaa gttcgccgtg    960

tcccaccaag attctctatc ccacccacta atcatgaaat catgccaggc ggaagcgtta   1020

atatcacctg tgtggccgtg gggtcaccaa tgccttatgt aaagtggatg ttgggggcag   1080

aagatctgac acctgaagat gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg   1140

taagacagtc agcaaattac acctgtgttg ctatgtcaac actgggtgtc attgaagcaa   1200

tagcacagat cactgtcaaa gccttaccca aacctccagg aactcctgta gtgaccgaga   1260

gcacagctac aagcatcaca ctgacgtggg actctgggaa ccctgagcct gtttcttatt   1320

acataattca gcataaacct aaaaactctg aggaacttta caaagaaatt gatggggtgg   1380

cgaccacacg ctacagtgtc gctggactaa gtccctactc ggattatgaa ttcagggttg   1440

ttgctgtcaa taacattggg cgggggcctc ccagcgaacc tgtgctaaca caaacctcag   1500

agcaagcacc atccagtgcc ccgagggatg tccaggcacg aatgttgagt tcgaccacca   1560

ttttggtaca gtggaaggaa cctgaagagc caaatggaca gatccaagga tatagagttt   1620

attatacaat ggatcccact caacatgtca acaactggat gaaacacaat gtagctgaca   1680

gccaaatcac tactattggc aacttagtgc cccagaaaac atattctgtc aaagtcctgg   1740

cttttacctc aattggagat ggtccccttt caagtgacat acaagtcatc actcagacag   1800

gagtaccagg gcagccacta aacttcaaag cagaacctga gtctgaaaca agtattttgc   1860

tctcttggac acctccacgt tcagatacca ttgccaacta tgaactggtc tacaaagatg   1920

gggagcatgg agaggagcaa cgaattacca ttgagccagg gacatcatat aggctgcaag   1980

gactgaaacc aaacagctta tactatttcc gtctggctgc acgctcccct caaggcctgg   2040

gtgcttctac tgcagaaata tcagctagaa ccatgcagtc aaagccgtca gctcctcctc   2100

aagacattag ttgcaccagc ccaagttcca ctagtatttt ggtaagttgg caacctccac   2160

cagtggaaaa acagaatggc attatcactg aatactccat caagtacact gcagtggatg   2220

gggaagatga caagcctcac gagattttgg gaattccttc ggacactacc aaataccttt   2280

tggaacagct ggaaaaatgg actgaatacc ggatcactgt gacagcccat acagatgtcg   2340

gccctggccc tgagagcttg tccgtgttga ttcgaaccaa tgaagatgtt cctagtggtc   2400

ctcctcgcaa agtcgaggta gaggctgtca actcaacatc tgttaaagtc tcatggcgct   2460

cacccgtgcc caataaacag catggccaga taagaggata tcaggtgcat tatgtgagga   2520

tggaaaatgg tgagcccaag ggccagccca tgctgaaaga tgtcatgctg gctgatgcac   2580

aggacatgat catttctggg ctccagcctg aaacttccta ctccctcacc gtcacagcct   2640

acacaaccaa aggagatggt gctcgcagca agcccaaact ggtgtccacc actggggcag   2700

ttccagggaa acctcggctt gtgattaacc acactcagat gaatactgct cttattcagt   2760

ggcaccctcc ggtggacaca tttggacctc ttcagggcta ccgtctaaaa tttggccgca   2820

aggatatgga gccacttact actcttgagt tctctgaaaa agaagatcac tttacagcta   2880

cagacatcca caagggagca tcatacgtct tcaggctctc agccagaaac aaagtgggct   2940

ttggggagga gatggtgaag gagatttcca ttccagaaga agtaccaact ggattccctc   3000

aaaaccttca ctcagaaggc accacttcaa cctccgtcca gttatcttgg caaccacctg   3060

tcctggcaga gagaaatggc attatcacca agtataccct tctttatagg gatatcaaca   3120

tcccccttct cccgatggag cagcttattg ttccagctga caccactatg acactcactg   3180

gcttaaaacc agataccaca tacgatgtaa aagtacgtgc tcatacgagc aaagggcccg   3240

ggccatatag tcccagtgtc cagttcagga cactgcctgt ggatcaagtg tttgcaaaaa   3300

attttcatgt caaagcagta atgaagactt ccgtgttgct gtcttgggag attccagaga   3360

attataactc cgccatgcct ttcaaaattc tttatgatga tgggaaaatg gtagaagaag   3420

tggatggccg agccacacag aagttaattg tcaacctgaa gcctgagaaa tcatattcat   3480

ttgtgctgac aaatcgtgga aacagtgctg gtgggctgca gcacagggtc acggcaaaga   3540

ctgcaccaga tgtattacgt accaagcctg ccttcattgg gaagaccaac ttggatggca   3600

tgattactgt gcaactgcct gaagtacctg caaatgagaa tataaaaggt tactacataa   3660

taattgtgcc tttgaagaaa tctcgcggga aatttatcaa gccatgggag agtccagatg   3720

aaatggaatt agatgagctg cttaaggaga tatctaggaa gcgcagaagc atccgttatg   3780

ggagagaagt tgaattaaag ccatatattg ccgctcactt tgatgtcctt cccactgagt   3840

tcaccctggg ggatgacaag cattatggtg gatttacaaa caagcaactc caaagtggtc   3900

aagaatatgt cttctttgtg ttagcagtaa tggaacatgc agagtctaag atgtatgcaa   3960

ccagccctta ctccgacccc gtggtgtcaa tggatctgga tccgcagcca atcacggatg   4020

aagaagaagg cttgatctgg gttgtaggtc ctgtccttgc agtggtcttt atcatctgca   4080

ttgtcattgc tattcttctt tataaaagga agagggcaga gtccgactct agaaaaagca   4140

gcataccgaa caataaggag atcccttcac accacccaac agaccctgta gaactgaggc   4200

gccttaactt tcaaacaccg ggtatggcta gccatcctcc aatacccatc ttggaacttg   4260

cagaccacat tgaaagattg aaagcaaatg acaacttgaa gttttcccag gaatatgagt   4320

caattgaccc tggccagcag ttcacttggg aacattcaaa cttggaagta aacaaaccaa   4380

agaatagata cgcgaatgta atcgcatatg atcattcccg ggttctccta tcagctatag   4440

aagggatccc aggaagtgac tatgtgaatg ccaactacat agatgggtat aggaagcaaa   4500

atgcctatat tgcaacacag ggatctctcc ccgaaacatt tggggacttt tggagaatga   4560

tatgggaaca acggagtgcc acagttgtca tgatgacaaa actagaagaa agatcaaggg   4620

tgaagtgtga ccagtattgg cctagcagag gcacagaaac ccacggactc gttcaagtaa   4680

cgctgcttga tactgtggag ctggccacat attgtgttcg aacatttgca ctttacaaga   4740

atggttcaag tgagaagaga gaagtgagac aattccagtt caccgcctgg cctgatcatg   4800

gtgttccaga acaccctaca ccttttctag ctttcttacg tagagtcaaa acctgtaacc   4860

ctcccgatgc tggtccgatg gttgtgcact gcagtgcggg agttggccgg actggttgct   4920

tcatcgtcat agatgccatg ttagaaagaa taaagcatga aaaaactgta gatatttatg   4980

gccatgtaac tttaatgaga gcccagagga actatatggt tcaaacagaa gaccaataca   5040

tctttatcca tgatgcactg ttagaagcag tgacttgtgg aaataccgaa gtgccagcta   5100

gaaacttgta tgcctacatt cagaagctga cacaaataga aacgggagag aatgtcacag   5160

gaatggagct cgaatttaag cgtctagcca gctcaaaagc tcacacctca aggtttatca   5220

gtgccaatct tccatgtaat aaattcaaaa atcgccttgt taatattatg ccatatgaat   5280

ccacaagggt atgcctgcag cctatccgtg gagtagaagg atctgattac atcaatgcca   5340

gttttattga tggatacaga caacagaaag cctacatcgc tacccagggg cccttggcag   5400

agaccactga agacttctgg cggatgctct gggaacacaa ttccaccata gttgtgatgc   5460

tcaccaagct gcgtgaaatg ggcagagaga aatgtcacca atactggcca gcagaacggt   5520

ctgcaagata ccagtacttt gttgtagatc ccatggctga gtacaacatg ccacagtata   5580

tcctaaggga attcaaggtc acagatgcca gggacggcca gtcccgaaca gtaaggcagt   5640

tccagttcac tgactggcca gagcaaggag tgccaaagtc cggagaagga tttattgact   5700

tcatcggcca agtccataaa acaaaagaac agtttggcca agatggaccc atttcagtcc   5760

attgcagcgc gggcgttgga agaactggag tcttcataac gctaagcatt gttttggaaa   5820

gaatgagata tgaaggagtt gtagatatct tccagactgt caaaatgtta agaacacaac   5880

gaccagctat ggtacagaca gaggatcaat atcagttttc ctatcgtgcc gcactagagt   5940

acctgggcag ctttgaccac tatgcaacgt agaaacccct gacccattct ggatttttac   6000

tacaggccct tcaatatcca tggagtctct tctgagccat acagggcact tgagaagtcc   6060

ttcttaactt ctagctaaca actacttagt gggactatta cacacaaaac aaattaaaaa   6120

caaattattc caggtggacc aagaatctgc tttgacatcg ccccttccca ccatactgct   6180

cataataaca ttttaggggg aaaggggagg gaatgtttaa aaagaaagtc cttgatttag   6240

ttttttagta ttgtaaagat actgctgacc tgtgcttcat ttctaactgt gtaaactttt   6300

ttttaacaaa atgtatcatt cgataaagtg aattttaaaa aagttacata actcttcatt   6360

tttttatttc caaatcgtag gtttttttaa gctgtagaac tgttatctgt aatatcttgc   6420

tgtagaaata tcaaatcatt tgaaaatttg cacatttttg tgcaaaactc aatctacagt   6480

atcagtctcg tcagatatat taattttaca cttcagtttt gattggtgag aaagtaccca   6540

ttctcttcaa ataatcaaag ataattatta ttttgttttg tttttggaat caacagggag   6600

gcgcaaagta taaagttgct gctaacatat atacatatat atccatattt tataagggtg   6660

tctatgtata tatagacagt gtgtccacac aaaaaataga tacagttatc agtcagtcag   6720

ttcttccatg atttagtttt tttaaacgta gaaaagctat tgtaaacatc tctttccatt   6780

tattcttaat tttttgacat attggtattt ctttaaaggg aaatgaggaa tgcacatcag   6840

tgattgattg tcaaacctca ccccctgatt tcctacctaa tctaccccca cctaaccaat   6900

caatcacatc cacaaattgt tttgtttgtt tgttagtcag gcttccaaca aagttcaata   6960

tttctaacac tctagtgcaa taaaaattat tattaaatag ctaagaggtg tgcatgtggg   7020

aaaggtcagt gcatatccct ttaggagggg agaatgttgt aatatatcag ctatcgagtt   7080

gtttaaaaaa agtgtattca atcgtatatt gtctatagta tgtgctatga aatttgcatt   7140

tatgatatgt aacaggggca aagccaaatt catgttactc tgttcagtca gaaacatttt   7200

gtggcataca gcattcctgg gaagtgctgt actttgtttc gttttggttt tagttttgca   7260

tttagagtgc cttataattg atgcctattt taatagcatt tctttttagc ttttggttcg   7320

tatttccatt cactgttcgt atctgttact ttctattaaa gcattatctg tttaccac     7378


<210>  6023
<211>  1656
<212>  PRT
<213>  Homo sapiens

<400>  6023

Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val Gly Ser Pro 
1               5                   10                  15


Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu Thr Pro Glu 
            20                  25                  30


Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn Asp Val Arg 
        35                  40                  45


Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu Gly Val Ile 
    50                  55                  60


Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys Pro Pro Gly 
65                  70                  75                  80


Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr Leu Thr Trp 
                85                  90                  95


Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile Gln His Lys 
            100                 105                 110


Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly Val Ala Thr 
        115                 120                 125


Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp Tyr Glu Phe 
    130                 135                 140


Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro Ser Glu Pro 
145                 150                 155                 160


Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala Pro Arg Asp 
                165                 170                 175


Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val Gln Trp Lys 
            180                 185                 190


Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg Val Tyr Tyr 
        195                 200                 205


Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys His Asn Val 
    210                 215                 220


Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro Gln Lys Thr 
225                 230                 235                 240


Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp Gly Pro Leu 
                245                 250                 255


Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro Gly Gln Pro 
            260                 265                 270


Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile Leu Leu Ser 
        275                 280                 285


Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu Leu Val Tyr 
    290                 295                 300


Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile Glu Pro Gly 
305                 310                 315                 320


Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu Tyr Tyr Phe 
                325                 330                 335


Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser Thr Ala Glu 
            340                 345                 350


Ile Ser Ala Arg Thr Met Gln Ser Lys Pro Ser Ala Pro Pro Gln Asp 
        355                 360                 365


Ile Ser Cys Thr Ser Pro Ser Ser Thr Ser Ile Leu Val Ser Trp Gln 
    370                 375                 380


Pro Pro Pro Val Glu Lys Gln Asn Gly Ile Ile Thr Glu Tyr Ser Ile 
385                 390                 395                 400


Lys Tyr Thr Ala Val Asp Gly Glu Asp Asp Lys Pro His Glu Ile Leu 
                405                 410                 415


Gly Ile Pro Ser Asp Thr Thr Lys Tyr Leu Leu Glu Gln Leu Glu Lys 
            420                 425                 430


Trp Thr Glu Tyr Arg Ile Thr Val Thr Ala His Thr Asp Val Gly Pro 
        435                 440                 445


Gly Pro Glu Ser Leu Ser Val Leu Ile Arg Thr Asn Glu Asp Val Pro 
    450                 455                 460


Ser Gly Pro Pro Arg Lys Val Glu Val Glu Ala Val Asn Ser Thr Ser 
465                 470                 475                 480


Val Lys Val Ser Trp Arg Ser Pro Val Pro Asn Lys Gln His Gly Gln 
                485                 490                 495


Ile Arg Gly Tyr Gln Val His Tyr Val Arg Met Glu Asn Gly Glu Pro 
            500                 505                 510


Lys Gly Gln Pro Met Leu Lys Asp Val Met Leu Ala Asp Ala Gln Asp 
        515                 520                 525


Met Ile Ile Ser Gly Leu Gln Pro Glu Thr Ser Tyr Ser Leu Thr Val 
    530                 535                 540


Thr Ala Tyr Thr Thr Lys Gly Asp Gly Ala Arg Ser Lys Pro Lys Leu 
545                 550                 555                 560


Val Ser Thr Thr Gly Ala Val Pro Gly Lys Pro Arg Leu Val Ile Asn 
                565                 570                 575


His Thr Gln Met Asn Thr Ala Leu Ile Gln Trp His Pro Pro Val Asp 
            580                 585                 590


Thr Phe Gly Pro Leu Gln Gly Tyr Arg Leu Lys Phe Gly Arg Lys Asp 
        595                 600                 605


Met Glu Pro Leu Thr Thr Leu Glu Phe Ser Glu Lys Glu Asp His Phe 
    610                 615                 620


Thr Ala Thr Asp Ile His Lys Gly Ala Ser Tyr Val Phe Arg Leu Ser 
625                 630                 635                 640


Ala Arg Asn Lys Val Gly Phe Gly Glu Glu Met Val Lys Glu Ile Ser 
                645                 650                 655


Ile Pro Glu Glu Val Pro Thr Gly Phe Pro Gln Asn Leu His Ser Glu 
            660                 665                 670


Gly Thr Thr Ser Thr Ser Val Gln Leu Ser Trp Gln Pro Pro Val Leu 
        675                 680                 685


Ala Glu Arg Asn Gly Ile Ile Thr Lys Tyr Thr Leu Leu Tyr Arg Asp 
    690                 695                 700


Ile Asn Ile Pro Leu Leu Pro Met Glu Gln Leu Ile Val Pro Ala Asp 
705                 710                 715                 720


Thr Thr Met Thr Leu Thr Gly Leu Lys Pro Asp Thr Thr Tyr Asp Val 
                725                 730                 735


Lys Val Arg Ala His Thr Ser Lys Gly Pro Gly Pro Tyr Ser Pro Ser 
            740                 745                 750


Val Gln Phe Arg Thr Leu Pro Val Asp Gln Val Phe Ala Lys Asn Phe 
        755                 760                 765


His Val Lys Ala Val Met Lys Thr Ser Val Leu Leu Ser Trp Glu Ile 
    770                 775                 780


Pro Glu Asn Tyr Asn Ser Ala Met Pro Phe Lys Ile Leu Tyr Asp Asp 
785                 790                 795                 800


Gly Lys Met Val Glu Glu Val Asp Gly Arg Ala Thr Gln Lys Leu Ile 
                805                 810                 815


Val Asn Leu Lys Pro Glu Lys Ser Tyr Ser Phe Val Leu Thr Asn Arg 
            820                 825                 830


Gly Asn Ser Ala Gly Gly Leu Gln His Arg Val Thr Ala Lys Thr Ala 
        835                 840                 845


Pro Asp Val Leu Arg Thr Lys Pro Ala Phe Ile Gly Lys Thr Asn Leu 
    850                 855                 860


Asp Gly Met Ile Thr Val Gln Leu Pro Glu Val Pro Ala Asn Glu Asn 
865                 870                 875                 880


Ile Lys Gly Tyr Tyr Ile Ile Ile Val Pro Leu Lys Lys Ser Arg Gly 
                885                 890                 895


Lys Phe Ile Lys Pro Trp Glu Ser Pro Asp Glu Met Glu Leu Asp Glu 
            900                 905                 910


Leu Leu Lys Glu Ile Ser Arg Lys Arg Arg Ser Ile Arg Tyr Gly Arg 
        915                 920                 925


Glu Val Glu Leu Lys Pro Tyr Ile Ala Ala His Phe Asp Val Leu Pro 
    930                 935                 940


Thr Glu Phe Thr Leu Gly Asp Asp Lys His Tyr Gly Gly Phe Thr Asn 
945                 950                 955                 960


Lys Gln Leu Gln Ser Gly Gln Glu Tyr Val Phe Phe Val Leu Ala Val 
                965                 970                 975


Met Glu His Ala Glu Ser Lys Met Tyr Ala Thr Ser Pro Tyr Ser Asp 
            980                 985                 990


Pro Val Val Ser Met Asp Leu Asp Pro Gln Pro Ile Thr Asp Glu Glu 
        995                 1000                1005


Glu Gly Leu Ile Trp Val Val Gly Pro Val Leu Ala Val Val Phe Ile 
    1010                1015                1020


Ile Cys Ile Val Ile Ala Ile Leu Leu Tyr Lys Arg Lys Arg Ala Glu 
1025                1030                1035                1040


Ser Asp Ser Arg Lys Ser Ser Ile Pro Asn Asn Lys Glu Ile Pro Ser 
                1045                1050                1055


His His Pro Thr Asp Pro Val Glu Leu Arg Arg Leu Asn Phe Gln Thr 
            1060                1065                1070


Pro Gly Met Ala Ser His Pro Pro Ile Pro Ile Leu Glu Leu Ala Asp 
        1075                1080                1085


His Ile Glu Arg Leu Lys Ala Asn Asp Asn Leu Lys Phe Ser Gln Glu 
    1090                1095                1100


Tyr Glu Ser Ile Asp Pro Gly Gln Gln Phe Thr Trp Glu His Ser Asn 
1105                1110                1115                1120


Leu Glu Val Asn Lys Pro Lys Asn Arg Tyr Ala Asn Val Ile Ala Tyr 
                1125                1130                1135


Asp His Ser Arg Val Leu Leu Ser Ala Ile Glu Gly Ile Pro Gly Ser 
            1140                1145                1150


Asp Tyr Val Asn Ala Asn Tyr Ile Asp Gly Tyr Arg Lys Gln Asn Ala 
        1155                1160                1165


Tyr Ile Ala Thr Gln Gly Ser Leu Pro Glu Thr Phe Gly Asp Phe Trp 
    1170                1175                1180


Arg Met Ile Trp Glu Gln Arg Ser Ala Thr Val Val Met Met Thr Lys 
1185                1190                1195                1200


Leu Glu Glu Arg Ser Arg Val Lys Cys Asp Gln Tyr Trp Pro Ser Arg 
                1205                1210                1215


Gly Thr Glu Thr His Gly Leu Val Gln Val Thr Leu Leu Asp Thr Val 
            1220                1225                1230


Glu Leu Ala Thr Tyr Cys Val Arg Thr Phe Ala Leu Tyr Lys Asn Gly 
        1235                1240                1245


Ser Ser Glu Lys Arg Glu Val Arg Gln Phe Gln Phe Thr Ala Trp Pro 
    1250                1255                1260


Asp His Gly Val Pro Glu His Pro Thr Pro Phe Leu Ala Phe Leu Arg 
1265                1270                1275                1280


Arg Val Lys Thr Cys Asn Pro Pro Asp Ala Gly Pro Met Val Val His 
                1285                1290                1295


Cys Ser Ala Gly Val Gly Arg Thr Gly Cys Phe Ile Val Ile Asp Ala 
            1300                1305                1310


Met Leu Glu Arg Ile Lys His Glu Lys Thr Val Asp Ile Tyr Gly His 
        1315                1320                1325


Val Thr Leu Met Arg Ala Gln Arg Asn Tyr Met Val Gln Thr Glu Asp 
    1330                1335                1340


Gln Tyr Ile Phe Ile His Asp Ala Leu Leu Glu Ala Val Thr Cys Gly 
1345                1350                1355                1360


Asn Thr Glu Val Pro Ala Arg Asn Leu Tyr Ala Tyr Ile Gln Lys Leu 
                1365                1370                1375


Thr Gln Ile Glu Thr Gly Glu Asn Val Thr Gly Met Glu Leu Glu Phe 
            1380                1385                1390


Lys Arg Leu Ala Ser Ser Lys Ala His Thr Ser Arg Phe Ile Ser Ala 
        1395                1400                1405


Asn Leu Pro Cys Asn Lys Phe Lys Asn Arg Leu Val Asn Ile Met Pro 
    1410                1415                1420


Tyr Glu Ser Thr Arg Val Cys Leu Gln Pro Ile Arg Gly Val Glu Gly 
1425                1430                1435                1440


Ser Asp Tyr Ile Asn Ala Ser Phe Ile Asp Gly Tyr Arg Gln Gln Lys 
                1445                1450                1455


Ala Tyr Ile Ala Thr Gln Gly Pro Leu Ala Glu Thr Thr Glu Asp Phe 
            1460                1465                1470


Trp Arg Met Leu Trp Glu His Asn Ser Thr Ile Val Val Met Leu Thr 
        1475                1480                1485


Lys Leu Arg Glu Met Gly Arg Glu Lys Cys His Gln Tyr Trp Pro Ala 
    1490                1495                1500


Glu Arg Ser Ala Arg Tyr Gln Tyr Phe Val Val Asp Pro Met Ala Glu 
1505                1510                1515                1520


Tyr Asn Met Pro Gln Tyr Ile Leu Arg Glu Phe Lys Val Thr Asp Ala 
                1525                1530                1535


Arg Asp Gly Gln Ser Arg Thr Val Arg Gln Phe Gln Phe Thr Asp Trp 
            1540                1545                1550


Pro Glu Gln Gly Val Pro Lys Ser Gly Glu Gly Phe Ile Asp Phe Ile 
        1555                1560                1565


Gly Gln Val His Lys Thr Lys Glu Gln Phe Gly Gln Asp Gly Pro Ile 
    1570                1575                1580


Ser Val His Cys Ser Ala Gly Val Gly Arg Thr Gly Val Phe Ile Thr 
1585                1590                1595                1600


Leu Ser Ile Val Leu Glu Arg Met Arg Tyr Glu Gly Val Val Asp Ile 
                1605                1610                1615


Phe Gln Thr Val Lys Met Leu Arg Thr Gln Arg Pro Ala Met Val Gln 
            1620                1625                1630


Thr Glu Asp Gln Tyr Gln Phe Ser Tyr Arg Ala Ala Leu Glu Tyr Leu 
        1635                1640                1645


Gly Ser Phe Asp His Tyr Ala Thr 
    1650                1655


<210>  6024
<211>  2401
<212>  DNA
<213>  Homo sapiens

<400>  6024
cggcgccgcc agccagcctc ggcggggaga gtgcagttta ttctgggcct gtgtggaata     60

gaaagacaat tctttatttg actggtagga aagaaaagag aagactcctc agggtttcca    120

aggaggactg gagcggctgc tttagtgaag aagtgaagaa tcaaggaagt aaaggacctg    180

tctcaaagtc acacaactag gaaatcttga ggagtctgat acttttcatc ctccagctat    240

aaaatcatct tgtaggggga agctgtacat tggtggaaaa taaaaggcaa gcagttcctg    300

gcccgtgata ttccagttag aggtgtctga ctgacagcat gttggcaccg agggaagcga    360

tgggcttcgg ctccaggttt ctgtcctgag accacagcag aatgtgcctt ggacaaaggc    420

ttggactcct tgatcttctg gtaacttcaa aaatctggtc tcagggtggt gaactttttc    480

ttcgaattcc taacctgtga gcttacgaaa aagggagcat gcctgtctta ttctcagtgc    540

ctcatgggaa ataaaagatt gggagatgat agctacctga tgatggtgcc tgtccattaa    600

ctgaacaact gtggttttga acttcttgag gccagggact gtgtctgaaa acaccgacgg    660

tggctaactc aagggagacg tctggtgaac acccgtggga tctaaagaac aagctctgaa    720

agtgttccag ctgaaatttc agatcggaca gactcgctgc ggctccggag gcagtgattc    780

caagctgctc gcgcacgctg ctgccaagct gcaggatggt gcacgtagcc aggctgctgc    840

tgctgctcct cactttcttc ctccgcacgg atgctgagac acctccaagg tttacacgaa    900

cacccgttga tcagacaggg gtctctggcg gagttgcctc tttcatctgc caagctacgg    960

gagacccaag acctaaaatt gtctggaaca aaaaaggaaa gaaagtcagc aatcagagat   1020

ttgaggtaat agagtttgac gatgggtctg gatcagttct cagaatacaa cccttacgga   1080

ctccgaggga tgaggccatt tatgaatgtg tggcctcaaa taatgtggga gaaataagtg   1140

tatccaccag actcacagtt ttgcgggaag atcaaattcc caggggcttc cctaccattg   1200

acatgggccc acagttgaag gtggttgagc gtactcgcac ggccaccatg ctttgtgcag   1260

ccagtggtaa tccggatcca gaaatcactt ggtttaaaga tttcttacct gtggacacaa   1320

gcaacaacaa tggtcgtatt aagcagttac gatcaggtac tgatttttct ccctcttctc   1380

tttctctgtt acttaatggg tggtccatgt ttgtgatgtc atagcctgtt tcagagtctg   1440

tctttctcct tttctctgtg tgttttgcag cttctgttta atccacattg ctcactgctg   1500

tgactgtatt tttggtaatt ttttaattta ctgctttttc gcagtatttg atggatccat   1560

tttctcctct ttctttcttc tttctctgtt ttcttttgaa acaaatttat ttcaacattg   1620

gacttcattc agaacttgca aggagatcca atggttgtat ccattaaaaa ataaaatgtt   1680

catattaaac cctaaaatgt ttcaatttta ttaaagtatg ttttctgcta tcttttctac   1740

atttgaactc atcaaagtac caaagtttag taagtctggg cacatctgct ttcttttcac   1800

taatacataa aaacacagaa acgttatctc atgagtaacc agatgtatgt ttttaaaagt   1860

ctttagaaaa taccagtaaa aggaggggat ttttattaat actatgataa taacattgtg   1920

agtgaacatt ttctacacat tagccacagt agtgtgcgcc cgtcaaggtt tttgaaccct   1980

ccagtgactg gatctacaga agtctgcttt tggtgtagac tccagctttt gctgttttct   2040

ctctctcttt acccttttct ccttttccca ttcccatccc aagtttatgc ctttgctctc   2100

ttagattaaa agtagagata attctaaatt tcttaagttt tagagcctgt ccctaggtaa   2160

tttcacaggg atatataata ataagctgtt tactttgaca ttggtagtaa tattggtata   2220

gaattctaag ttgtttaact gcctgtcttc ccagaattct cagcttttga cctgtcctgt   2280

gatgttaaag cgtcttgtta actgcctctt ttgcttgttg tcagcagaat tgtgtagatt   2340

agcattctgt tattgtaaat gaagaattaa ttattcacat gtaacataga tgatttagta   2400

t                                                                   2401


<210>  6025
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  6025

Met Val His Val Ala Arg Leu Leu Leu Leu Leu Leu Thr Phe Phe Leu 
1               5                   10                  15


Arg Thr Asp Ala Glu Thr Pro Pro Arg Phe Thr Arg Thr Pro Val Asp 
            20                  25                  30


Gln Thr Gly Val Ser Gly Gly Val Ala Ser Phe Ile Cys Gln Ala Thr 
        35                  40                  45


Gly Asp Pro Arg Pro Lys Ile Val Trp Asn Lys Lys Gly Lys Lys Val 
    50                  55                  60


Ser Asn Gln Arg Phe Glu Val Ile Glu Phe Asp Asp Gly Ser Gly Ser 
65                  70                  75                  80


Val Leu Arg Ile Gln Pro Leu Arg Thr Pro Arg Asp Glu Ala Ile Tyr 
                85                  90                  95


Glu Cys Val Ala Ser Asn Asn Val Gly Glu Ile Ser Val Ser Thr Arg 
            100                 105                 110


Leu Thr Val Leu Arg Glu Asp Gln Ile Pro Arg Gly Phe Pro Thr Ile 
        115                 120                 125


Asp Met Gly Pro Gln Leu Lys Val Val Glu Arg Thr Arg Thr Ala Thr 
    130                 135                 140


Met Leu Cys Ala Ala Ser Gly Asn Pro Asp Pro Glu Ile Thr Trp Phe 
145                 150                 155                 160


Lys Asp Phe Leu Pro Val Asp Thr Ser Asn Asn Asn Gly Arg Ile Lys 
                165                 170                 175


Gln Leu Arg Ser Gly Thr Asp Phe Ser Pro Ser Ser Leu Ser Leu Leu 
            180                 185                 190


Leu Asn Gly Trp Ser Met Phe Val Met Ser 
        195                 200


<210>  6026
<211>  717
<212>  DNA
<213>  Homo sapiens

<400>  6026
agattcacag gtacatgtgg acgtttgtta cctgggcata ctgcatgacg ccgaggcttg     60

ggatatgaat catctcatct cccagcccct ggcaaccacc atcgtactct ctgcatctgt    120

atgttcagct ttttggattc catacaagac atcttcaaat caattgatgg aagattgaga    180

gaaagagaac ttcaggtcca ggtgctgtgg ctcatgcctg taatcccagc actttgggtg    240

actgagaatt tcagaagaga aagagtctct cagcatttct cactggacat gcctgaagaa    300

gcatgtagtc ttaattgcta ctgacatcat cccataacca caatggaaaa ggactggaga    360

tattgtctga gagctcttgt tatgtgctaa ccatcctgtt ggacaatggg aacaaagata    420

tgagactcct tcaaggaagg actcaagcta ccaaaggtaa agctttgaaa aactattaca    480

ggcatttctt gaaaacagta tggaatcatc tgataacact gaggtgatat gaatactcct    540

ttaaccggca atgtggctct taggaactga tgggcatgca catcaggata tacacaaaag    600

atttcccagc agcactgttt gtaatagcct tgagctagaa acaataaatg tccaccaaga    660

gtaaaatgta taaaatatac aatggaatac cagacatcaa tgaaaatgaa taaacta       717


<210>  6027
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  6027

Met Phe Ser Phe Leu Asp Ser Ile Gln Asp Ile Phe Lys Ser Ile Asp 
1               5                   10                  15


Gly Arg Leu Arg Glu Arg Glu Leu Gln Val Gln Val Leu Trp Leu Met 
            20                  25                  30


Pro Val Ile Pro Ala Leu Trp Val Thr Glu Asn Phe Arg Arg Glu Arg 
        35                  40                  45


Val Ser Gln His Phe Ser Leu Asp Met Pro Glu Glu Ala Cys Ser Leu 
    50                  55                  60


Asn Cys Tyr 
65


<210>  6028
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  6028
agtgctccag gaggcagaga aaatgaagga aaacagcttt ctacagctct tacccccaca     60

acccccatct ctctgtaact taatttttct tctcaagttt cgaacaagta cagatagaac    120

aacttgtttt ctaatctttt tctctttttc tcattcctct tctttcttta ttcttctttt    180

cccccctctt tttgtttcct tttcctgact cttgaaaacc atggcaagtg cttattattt    240

cagttgaata tgttaaaaat tgttatcaag aagttgattt tttgtgtata aaaatggtga    300

actaagatac tgttaaaaga gtggaataaa tgaagaggag agacagaaga accaaagatg    360

ggaaaaggac tggaaaagaa aaagagacta aaaggaagag gctgaaaact taaaaaattg    420

gatgaaaatt atgaagatag tctgacatga tatattaaga gctctgaatg atgcctaggg    480

atgtagaaga ggagaaaaac acttgaggaa gagagaccaa agagaattct actttgaccc    540

tggcttaaga gtg                                                       553


<210>  6029
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  6029

Met Lys Glu Asn Ser Phe Leu Gln Leu Leu Pro Pro Gln Pro Pro Ser 
1               5                   10                  15


Leu Cys Asn Leu Ile Phe Leu Leu Lys Phe Arg Thr Ser Thr Asp Arg 
            20                  25                  30


Thr Thr Cys Phe Leu Ile Phe Phe Ser Phe Ser His Ser Ser Ser Phe 
        35                  40                  45


Phe Ile Leu Leu Phe Pro Pro Leu Phe Val Ser Phe Ser 
    50                  55                  60


<210>  6030
<211>  621
<212>  DNA
<213>  Homo sapiens

<400>  6030
ctcggacaat gcacacaaaa gcctggttaa ggagcacttc caaagtcatt ccttcctcac     60

cccaccaatg accactatgc ataaaggaaa agccaagttt gagaaggaga atttcttaga    120

tgtcctggac gtgctcatcc tcaccctctc tagaagattc aagatgaaga aactgggaga    180

ctacagctca gtataagtag aaatagtgag aggtgaccac gggctagcag ccctggctcg    240

ctctcagcac ctcctcagtc ttgtcgtctg ctctggccat gctcgaggag ccctttagcc    300

caccactaca ctgttggagc ccctctctgg gctagctgag gctggagccg gctccctctg    360

cttgtgggaa ggagtggagg gacaggcaca ggcgggaacc ggggctgcgc accacgtttg    420

cggaccaggg caagttccgg gtgggcgtgg gctcggcggg cctcacactc acagctgccg    480

gccagcgcct cgggccctgt gcagtgaggg tcttagcacc ctggccagca gctgcggagg    540

gggcgctggg tcctcgaaca ctgacagccc acccccacca cgcttgaatt ctcgccgggc    600

ctcagccgcc tccccgcggg g                                              621


<210>  6031
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  6031

Met Thr Thr Met His Lys Gly Lys Ala Lys Phe Glu Lys Glu Asn Phe 
1               5                   10                  15


Leu Asp Val Leu Asp Val Leu Ile Leu Thr Leu Ser Arg Arg Phe Lys 
            20                  25                  30


Met Lys Lys Leu Gly Asp Tyr Ser Ser Val 
        35                  40


<210>  6032
<211>  2322
<212>  DNA
<213>  Homo sapiens

<400>  6032
attaacttag cgcccggggt ctctgccagg ctcacgggac agctgcacct ctcagcgtct     60

ccagctccag gacgcggtcg tcccaactcc ttccgagtgg aaagagtgta aaacttttgt    120

ccgtgcgcgg gtggagctca gtaggaccac ggcgcgtcct gccccggctt ccccagcctc    180

ccagcagggt tagctgcggt cagcgcactt tccacttggg actcccggcc agaaatttct    240

cgggaatgga gcggtcacag tgtggcagca gagaccgagg cgttagcggc cgacctcact    300

tggcccctgg gctagtggtg gctgcccctc cgcccccgtc cccggcgttg ccggtaccat    360

cggggatgca ggttccccca gcgttcctgc ggccgcccag cctctttctg cgagcagcgg    420

ccgcggccgc cgccgccgct gccgccacct cgggaagcgg aggctgcccg ccggctcccg    480

ggctggagag cggggtaggc gcggtgggct gcggctaccc gcggacgccc aagtgcgccc    540

gctgtcgtaa ccatggtgtg gtgtcagcgc tcaagggcca caagcgcttc tgccgctggc    600

gggactgcgc gtgtgccaag tgcaccctga tcgccgagcg ccagcgcgtc atggccgccc    660

aggtggcgct gcgcaggcag caggcgcagg aggagagcga agcccggggg ctacagaggc    720

tcctgtgctc ggggctctcc tggccccccg gtggtcgggc atccgggggc ggcggcagag    780

ccgagaatcc acagtccacg ggcggccctg cggcgggggc tgcgctggga ctgggtgcct    840

tgagacaggc cagtggttcc gcgacccccg ctttcgaagt tttccagcaa gattatcctg    900

aggaaaaaca agaacaaaaa gagagtaaat gtgagtcatg ccagaatgga caagaagaac    960

tgatctccaa atcccatcag ctttacctag gatcatcttc taggtctaat ggtgtcattg   1020

ggaaacaaag tatcgggtca tctatttcag aatactccaa caagcctgat agtatcctgt   1080

ctcctcatcc tggagagcaa tcaggaggtg aagagagtcc caggtcctta tcatcctctg   1140

atctggaatc aggaaatgaa agtgaatggg tcaaagactt gactgcgacc aaggcaagcc   1200

ttccgacagt gtcctcaaga ccaagagatc ctcttgatat ccttactaag attttcccaa   1260

attacaggcg cagccggcta gaaggcattc tacggttctg caaaggggat gtggtccaag   1320

ccattgaaca ggttttaaat ggcaaagaac acaagccaga caacaggaac ctagcaaact   1380

cagaagaact ggaaaacaca gcctttcaga gagcttcaag ttttagtctt gctggaattg   1440

gttttggaac tctaggtaat aaatcagctt tctctcctct tcaaactact tctgcttctt   1500

atggaggtga ttcaagtctc tacggcgtaa atcctagagt aggtatcagt ccattaaggc   1560

tggcatattc ttctgcagga agagggttat ctggttttat gtcaccctac ctaacacctg   1620

ggttagtacc aaccttacct tttcggccag ctttggatta tgccttttca gggatgatta   1680

gagattcttc ctacctttcc agtaaagact caataacttg tggcagactg tacttcagac   1740

caaatcagga caatccgtaa tgtatatgcc cattctctct ttctggagtt tttccagcat   1800

acaatacatg cacgtgcaca cacatacaca cacatccatt aatatacttc agtaagtatg   1860

tgagtggatt atgaggtctt aaaatgctgg gttttttttt tttcaagcaa tataataggt   1920

cttagatctg aaaactcttc attaggattt atcaagtgaa agaagtaaat ctgaacatta   1980

tatgtgcctt gaataaagct atttcaggaa atatttaatg aattttctcc ctaaattatc   2040

atttgtaaac atttttattt taaaactagt ttttatttta ttgaaaagtg gaatttttag   2100

tgataaaata catttgtaag tgtaaagcaa tacagcataa tagaatagaa tataaaccga   2160

aaggaagaac tgaacaatta aggcaattct aaataattac catttcaaaa ctgtttcttc   2220

tattcctggt tcataggaaa gaaaaaagtt attcaaagta tttttaaagc atttgatttg   2280

cagatgggtg attcgtaata aataaaacat ttgagcattt tg                      2322


<210>  6033
<211>  504
<212>  PRT
<213>  Homo sapiens

<400>  6033

Met Glu Arg Ser Gln Cys Gly Ser Arg Asp Arg Gly Val Ser Gly Arg 
1               5                   10                  15


Pro His Leu Ala Pro Gly Leu Val Val Ala Ala Pro Pro Pro Pro Ser 
            20                  25                  30


Pro Ala Leu Pro Val Pro Ser Gly Met Gln Val Pro Pro Ala Phe Leu 
        35                  40                  45


Arg Pro Pro Ser Leu Phe Leu Arg Ala Ala Ala Ala Ala Ala Ala Ala 
    50                  55                  60


Ala Ala Ala Thr Ser Gly Ser Gly Gly Cys Pro Pro Ala Pro Gly Leu 
65                  70                  75                  80


Glu Ser Gly Val Gly Ala Val Gly Cys Gly Tyr Pro Arg Thr Pro Lys 
                85                  90                  95


Cys Ala Arg Cys Arg Asn His Gly Val Val Ser Ala Leu Lys Gly His 
            100                 105                 110


Lys Arg Phe Cys Arg Trp Arg Asp Cys Ala Cys Ala Lys Cys Thr Leu 
        115                 120                 125


Ile Ala Glu Arg Gln Arg Val Met Ala Ala Gln Val Ala Leu Arg Arg 
    130                 135                 140


Gln Gln Ala Gln Glu Glu Ser Glu Ala Arg Gly Leu Gln Arg Leu Leu 
145                 150                 155                 160


Cys Ser Gly Leu Ser Trp Pro Pro Gly Gly Arg Ala Ser Gly Gly Gly 
                165                 170                 175


Gly Arg Ala Glu Asn Pro Gln Ser Thr Gly Gly Pro Ala Ala Gly Ala 
            180                 185                 190


Ala Leu Gly Leu Gly Ala Leu Arg Gln Ala Ser Gly Ser Ala Thr Pro 
        195                 200                 205


Ala Phe Glu Val Phe Gln Gln Asp Tyr Pro Glu Glu Lys Gln Glu Gln 
    210                 215                 220


Lys Glu Ser Lys Cys Glu Ser Cys Gln Asn Gly Gln Glu Glu Leu Ile 
225                 230                 235                 240


Ser Lys Ser His Gln Leu Tyr Leu Gly Ser Ser Ser Arg Ser Asn Gly 
                245                 250                 255


Val Ile Gly Lys Gln Ser Ile Gly Ser Ser Ile Ser Glu Tyr Ser Asn 
            260                 265                 270


Lys Pro Asp Ser Ile Leu Ser Pro His Pro Gly Glu Gln Ser Gly Gly 
        275                 280                 285


Glu Glu Ser Pro Arg Ser Leu Ser Ser Ser Asp Leu Glu Ser Gly Asn 
    290                 295                 300


Glu Ser Glu Trp Val Lys Asp Leu Thr Ala Thr Lys Ala Ser Leu Pro 
305                 310                 315                 320


Thr Val Ser Ser Arg Pro Arg Asp Pro Leu Asp Ile Leu Thr Lys Ile 
                325                 330                 335


Phe Pro Asn Tyr Arg Arg Ser Arg Leu Glu Gly Ile Leu Arg Phe Cys 
            340                 345                 350


Lys Gly Asp Val Val Gln Ala Ile Glu Gln Val Leu Asn Gly Lys Glu 
        355                 360                 365


His Lys Pro Asp Asn Arg Asn Leu Ala Asn Ser Glu Glu Leu Glu Asn 
    370                 375                 380


Thr Ala Phe Gln Arg Ala Ser Ser Phe Ser Leu Ala Gly Ile Gly Phe 
385                 390                 395                 400


Gly Thr Leu Gly Asn Lys Ser Ala Phe Ser Pro Leu Gln Thr Thr Ser 
                405                 410                 415


Ala Ser Tyr Gly Gly Asp Ser Ser Leu Tyr Gly Val Asn Pro Arg Val 
            420                 425                 430


Gly Ile Ser Pro Leu Arg Leu Ala Tyr Ser Ser Ala Gly Arg Gly Leu 
        435                 440                 445


Ser Gly Phe Met Ser Pro Tyr Leu Thr Pro Gly Leu Val Pro Thr Leu 
    450                 455                 460


Pro Phe Arg Pro Ala Leu Asp Tyr Ala Phe Ser Gly Met Ile Arg Asp 
465                 470                 475                 480


Ser Ser Tyr Leu Ser Ser Lys Asp Ser Ile Thr Cys Gly Arg Leu Tyr 
                485                 490                 495


Phe Arg Pro Asn Gln Asp Asn Pro 
            500


<210>  6034
<211>  3240
<212>  DNA
<213>  Homo sapiens

<400>  6034
aatttagaga agatgtaggg agtgttcaac atgttcgttg tggaagagaa agagctaaga     60

gagaggagct taaagacaca aacgggtaga atcaaggagt gtgctctcaa atgagaggaa    120

caggagtgac attaaccttg aaatgctcgg agactctact ccttcatgac agtaggagga    180

taattaacaa tagatacaaa tgcaggaatt gatgagtgcc atcagaaagc tgtatcatga    240

gctgcctgca cttctaaagt gtccagtgga tttttaatca catgagcctg gaaatagggt    300

tatgagaaga agctcagagc agagcaccga aagtggccac taccagcatg aagagcccaa    360

caattcaaac tggtgaagtg agaaaaacag aatgcagctt tcaaggttcg tttcaagcag    420

ttggcttgtg ggactctgag agatgctgct gcccatgaca tgcgggaatt atcatgatca    480

actacccagc ttggatttca cccagtggcc aagagctttg tgtgggagac ggcaagggtt    540

ggatttttca aaagagtaaa ccaggataaa tcatgaggaa cctataaccc ttttggccac    600

atgcaaaaaa gcaagacccg tgaccaaggt gtagactaag aagtggagtc atgcttcaca    660

cggccatatc atgctggcag ccattcctgg gtctggctgt ggtgttaatc ttcatgggat    720

ccaccattgg ctgccccgct cgctgtgagt gctctgccca gaacaaatct gttagctgtc    780

acagaaggcg attgatcgcc atcccagagg gcattcccat cgaaaccaaa atcttggacc    840

tcagtaaaaa caggctaaaa agcgtcaacc ctgaagaatt catatcatat cctctgctgg    900

aagagataga cttgagtgac aacatcattg ccaatgtgga accaggagca ttcaacaatc    960

tctttaacct gcgttccctc cgcctaaaag gcaatcgtct aaagctggtc cctttgggag   1020

tattcacggg gctgtccaat ctcactaagc ttgacattag tgagaataag attgtcattt   1080

tactagacta catgttccaa gatctacata acctgaagtc tctagaagtg ggggacaatg   1140

atttggttta tatatcacac agggcattca gtgggcttct tagcttggag cagctcaccc   1200

tggagaaatg caacttaaca gcagtaccaa cagaagccct ctcccacctc cgcagcctca   1260

tcagcctgca tctgaagcat ctcaatatca acaatatgcc tgtgtatgcc tttaaaagat   1320

tgttccacct gaaacaccta gagattgact attggccttt actggatatg atgcctgcca   1380

atagcctcta cggtctcaac ctcacatccc tttcagtcac caacaccaat ctgtctactg   1440

tacccttcct tgcctttaaa cacctggtat acctgactca ccttaacctc tcctacaatc   1500

ccatcagcac tattgaagca ggcatgttct ctgacctgat ccgccttcag gagcttcata   1560

tagtgggggc ccagcttcgc accattgagc ctcactcctt ccaagggctc cgcttcctac   1620

gcgtgctcaa tgtgtctcag aacctgctgg aaactttgga agagaatgtc ttctcctccc   1680

ctagggctct ggaggtcttg agcattaaca acaaccctct ggcctgtgac tgccgccttc   1740

tctggatctt gcagcgacag cccaccctgc agtttggtgg ccagcaacct atgtgtgctg   1800

gcccagacac catccgtgag aggtctttca aggatttcca tagcactgcc ctttcttttt   1860

actttacctg caaaaaaccc aaaatccgtg aaaagaagtt gcagcatctg ctagtagatg   1920

aagggcagac agtccagcta gaatgcagtg cagatggaga cccgcagcct gtgatttcct   1980

gggtgacacc ccgaaggcgt ttcatcacca ccaagtccaa tggaagagcc accgtgttgg   2040

gtgatggcac cttggaaatc cgctttgccc aggatcaaga cagcgggatg tatgtttgca   2100

tcgctagcaa tgctgctggg aatgatacct tcacagcctc cttaactgtg aaaggattcg   2160

cttcagatcg ttttctttat gcgaacagga cccctatgta catgaccgac tccaatgaca   2220

ccatttccaa tggcaccaat gccaatactt tttccctgga ccttaaaaca atactggtgt   2280

ctacagctat gggctgcttc acattcctgg gagtggtttt attttgtttt cttctccttt   2340

ttgtgtggag ccgagggaaa ggcaagcaca aaaacagcat tgaccttgag tatgtgccca   2400

gaaaaaacaa tggtgctgtt gtggaagggg aggtagctgg acccaggagg ttcaacatga   2460

aaatgatttg aaggcccacc cctcacatta ctgtctcttt gtcaatgtgg gtaatcagta   2520

agacagtatg gcacagtaaa ttactagatt aagaggcagc catgtgcagc tgcccctgta   2580

tcaaaagcag ggtctatgga agcaggagga cttccaatgg agactctcca tcgaaaggca   2640

ggcaggcagg catgtgtcag agcccttcac acagtgggat actaagtgtt tgcgttgcaa   2700

atattggcgt tctggggatc tcagtaatga acctgaatat ttggctcaca ctcacggaca   2760

attattcagc attttctacc actgcaaaaa acaaaagaaa aaataaaaaa gaacaaccta   2820

cagtgtagga tttacatatt aaaaagacac atttgtctaa aacatactct acagaaaaat   2880

ttgtatctat gattatcatt tgttaaagcc ttgcatcata ccatattgtt ggttcagtac   2940

cacaaagaga tcaatatatt cttttcttcc ttttttgaaa catatatgct gtacatgttt   3000

taaagcaata tgaatgagag gttgtgcttt tagttactca ccactataga tccaagtgtg   3060

atttcacctt ccgttaccta cagatgaccc tgagactaga tccctggagt tatgggcgga   3120

gatattttga gagatgtgtt tgtctgatgt aggatgccaa gaaacaggac ccaaggcaaa   3180

actgctcaac tctgttaact tctgttacta taaataaagg catgtgccta gttttgatac   3240


<210>  6035
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  6035

Met Lys Ser Pro Thr Ile Gln Thr Gly Glu Val Arg Lys Thr Glu Cys 
1               5                   10                  15


Ser Phe Gln Gly Ser Phe Gln Ala Val Gly Leu Trp Asp Ser Glu Arg 
            20                  25                  30


Cys Cys Cys Pro 
        35


<210>  6036
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  6036
gctttacaca tttatggcta gcctttcagc cctgccttgc tgagttacaa gtgaagtgag     60

aaaaacagaa tgcagctttc aaggttcgtt tcaagcagtt ggcttgtggg actctgagag    120

atgctgctgc ccatgacatg cgggaattat catgatcaac tacccagctt ggatttcacc    180

cagtggccaa gagctttgtg tgggagacgg caagggttgg atttttcaaa agagtaaacc    240

aggtggatac atttgcaaag tggaatcctc caggtgcctt taaggagttt acagtctagt    300

aggaactgca gaaagaattg aaaagaaaat aacggcaatg aaagccccat tctttagcca    360

gaaatatcct ttcacctaac aatctgacaa ctagttaaaa ccctatcatc ttccaatttc    420

atgtgctaag aggataaagg ataaatcatg aggaacctat aacccttttg gccacatgca    480

aaaaagcaag acccgtgacc aaggtgtaga ctaagaagtg gagtcatgct tcacacggcc    540

atatcatgct ggcagccatt cctgggtctg gct                                 573


<210>  6037
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  6037

Met Ile Asn Tyr Pro Ala Trp Ile Ser Pro Ser Gly Gln Glu Leu Cys 
1               5                   10                  15


Val Gly Asp Gly Lys Gly Trp Ile Phe Gln Lys Ser Lys Pro Gly Gly 
            20                  25                  30


Tyr Ile Cys Lys Val Glu Ser Ser Arg Cys Leu 
        35                  40


<210>  6038
<211>  887
<212>  DNA
<213>  Homo sapiens

<400>  6038
agctcctgag aagctgaggc cctgactcat ttttctagca tggcatttgg gtactcttca     60

cccaaaaaga gattcctaag tataactctt ggccggcctg gatgtctcat cacagaaaca    120

gcctatccag tcgtacctct tcagtcctca gactgggtcc tgcccatgtg aatggatcta    180

ggattacttc cctgactctt cccaactcac ttgacctatc tgcctgactt gatactgtga    240

gatggatagc tgaactctaa ggaaatggaa aattggaagc gctcttaggt gtttgattta    300

tgtatcaact gtatgagctc caataactca agacaactct ggatgaagct cgttctctga    360

tcttggccta aattcttatt ctgatggtgg aggtcaagga ggcaacatgc ctttgtttat    420

actgatatga cctcatcaga agataaacac ctgaagatgc agcagctcct gacttgcaca    480

tttataaata gctcctattt attaatggcc atcctctctt caaccacctg ctaaagttga    540

accacctgca cggcaattac aaagatgact gggccagagg gtatgggaag acgcctgaga    600

tgactatctt tcctgcaatt ttgcctggga aaagctctgc ttccggaaaa aaaattactg    660

ttatcttctc tatcaccaaa aattgggaca atcaaatttt ttctaaccct tttggatata    720

agaggcagtt aaaaaaaagt gacggagatt tcctagacat tcttatgttt tctatagaca    780

atgtttggag tatggtgaca agccaaggaa aatgcagaaa tggtcactat aactatagca    840

cctgcttcta tattcccata attaataaat aatgctattc ctactgt                  887


<210>  6039
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  6039

Met Thr Ser Ser Glu Asp Lys His Leu Lys Met Gln Gln Leu Leu Thr 
1               5                   10                  15


Cys Thr Phe Ile Asn Ser Ser Tyr Leu Leu Met Ala Ile Leu Ser Ser 
            20                  25                  30


Thr Thr Cys 
        35


<210>  6040
<211>  1322
<212>  DNA
<213>  Homo sapiens

<400>  6040
agatgcccag tgtgcacccg gccacagaga agtgggtgac ttaggagtat cctctccgct     60

tctgaccctt ggtttcgtct gtgcacaact cactcaaaat gggcaactca ttaagcatat    120

tttgttcctg gttccgccac aggtcctggc catgccattg gcaacctgct cgtcttgtcc    180

atgaggcctt cccagctggc cgggctaacc ccgcggctcc tgcacctgtg cctgcccggg    240

gaatcgtggg ccgtttccca ctcctcttca accctcagcg acatcttggg ccttcttttc    300

cagtcagttg ggacggcgcc cctatgaggc tgtgtcttat ccctcggaac atgggcaccc    360

cacagagggt cctgtctcct gtggtctgga gccccgcctc aaggaagaaa cccatgctgt    420

ctgctcacaa ctccaggatg tttggacacc tcagccccgt gaggattcct catctcagag    480

gcaagtttaa ccttcaactt ccttcattag atgagcaggt gatcccagcc aggctcccga    540

agatggaggt gagggcagaa gagcccagag aagcaacgga ggtgacagac caggtagaga    600

cccaggggca ggaggacaat aaaaggggcc cctgtagcaa tggggaagca gcttccacct    660

ctaggcccct ggagactcag ggaaacttca cttcctcctg gtacaatccc aggcccttgg    720

agggaaatgt ccacctcaag agcttgacag aaaacaacca gactgacaag gcccaggtgc    780

ctgcagtgag tttctactcc aacggccatg gagtcgccag ttcacacagc cctgctggag    840

gcatccttcc ctttgggaag cctgacccac ttccaacagt gctccctgcc ccagttccag    900

gctgctccct gtggccagag aaggcggcct tgaaggtgct gggtaaagac cacctgccca    960

gctctccagg cttgctgatg gtgggggagg acatgcagcc caaggatcct gcagctcttg   1020

ggtcaagtag gtcttctcca cacagagctg ccggccacag ttcccacaaa agaaaactgt   1080

cggggccacc gctgcagctg caaccgaccc ctcccctgca actgaggtgg gatagagacg   1140

aggggccccc accggctaag cttccatgtc tatctcctga ggcactgttg gtgggtcagg   1200

cttcccaaag agaaggacgc ctccagcagg gcaacatgtg taagaacatg agggtgttaa   1260

gtagaacatc aaaattcagg agagtaagag agctgcttag gaggagaaag aagagatggt   1320

ag                                                                  1322


<210>  6041
<211>  407
<212>  PRT
<213>  Homo sapiens

<400>  6041

Met Gly Asn Ser Leu Ser Ile Phe Cys Ser Trp Phe Arg His Arg Ser 
1               5                   10                  15


Trp Pro Cys His Trp Gln Pro Ala Arg Leu Val His Glu Ala Phe Pro 
            20                  25                  30


Ala Gly Arg Ala Asn Pro Ala Ala Pro Ala Pro Val Pro Ala Arg Gly 
        35                  40                  45


Ile Val Gly Arg Phe Pro Leu Leu Phe Asn Pro Gln Arg His Leu Gly 
    50                  55                  60


Pro Ser Phe Pro Val Ser Trp Asp Gly Ala Pro Met Arg Leu Cys Leu 
65                  70                  75                  80


Ile Pro Arg Asn Met Gly Thr Pro Gln Arg Val Leu Ser Pro Val Val 
                85                  90                  95


Trp Ser Pro Ala Ser Arg Lys Lys Pro Met Leu Ser Ala His Asn Ser 
            100                 105                 110


Arg Met Phe Gly His Leu Ser Pro Val Arg Ile Pro His Leu Arg Gly 
        115                 120                 125


Lys Phe Asn Leu Gln Leu Pro Ser Leu Asp Glu Gln Val Ile Pro Ala 
    130                 135                 140


Arg Leu Pro Lys Met Glu Val Arg Ala Glu Glu Pro Arg Glu Ala Thr 
145                 150                 155                 160


Glu Val Thr Asp Gln Val Glu Thr Gln Gly Gln Glu Asp Asn Lys Arg 
                165                 170                 175


Gly Pro Cys Ser Asn Gly Glu Ala Ala Ser Thr Ser Arg Pro Leu Glu 
            180                 185                 190


Thr Gln Gly Asn Phe Thr Ser Ser Trp Tyr Asn Pro Arg Pro Leu Glu 
        195                 200                 205


Gly Asn Val His Leu Lys Ser Leu Thr Glu Asn Asn Gln Thr Asp Lys 
    210                 215                 220


Ala Gln Val Pro Ala Val Ser Phe Tyr Ser Asn Gly His Gly Val Ala 
225                 230                 235                 240


Ser Ser His Ser Pro Ala Gly Gly Ile Leu Pro Phe Gly Lys Pro Asp 
                245                 250                 255


Pro Leu Pro Thr Val Leu Pro Ala Pro Val Pro Gly Cys Ser Leu Trp 
            260                 265                 270


Pro Glu Lys Ala Ala Leu Lys Val Leu Gly Lys Asp His Leu Pro Ser 
        275                 280                 285


Ser Pro Gly Leu Leu Met Val Gly Glu Asp Met Gln Pro Lys Asp Pro 
    290                 295                 300


Ala Ala Leu Gly Ser Ser Arg Ser Ser Pro His Arg Ala Ala Gly His 
305                 310                 315                 320


Ser Ser His Lys Arg Lys Leu Ser Gly Pro Pro Leu Gln Leu Gln Pro 
                325                 330                 335


Thr Pro Pro Leu Gln Leu Arg Trp Asp Arg Asp Glu Gly Pro Pro Pro 
            340                 345                 350


Ala Lys Leu Pro Cys Leu Ser Pro Glu Ala Leu Leu Val Gly Gln Ala 
        355                 360                 365


Ser Gln Arg Glu Gly Arg Leu Gln Gln Gly Asn Met Cys Lys Asn Met 
    370                 375                 380


Arg Val Leu Ser Arg Thr Ser Lys Phe Arg Arg Val Arg Glu Leu Leu 
385                 390                 395                 400


Arg Arg Arg Lys Lys Arg Trp 
                405


<210>  6042
<211>  1482
<212>  DNA
<213>  Homo sapiens

<400>  6042
gacgggactg ttaggttgcg ggctttgggg ctcactcccg acggcattgt cttctcctct     60

tctcagacag ggcagaccga ggagtttgga ccgagagttt atagaaacct attcaccaaa    120

atggcatcct ggttatatga atgtctttgt gaagctgaac ttgcacagta ttattctcat    180

ttcactgccc ttggccttca gaaaatagat gaattagcca agattacaat gaaggactac    240

tccaaattag gagtccatga catgaacgac cgcaaacgtc tcttccaact tatcaaaatt    300

attaagatta tgcaagaaga agataaagca gtcagtatcc cagagcgtca tcttcagaca    360

agcagcctgc gcatcaaatc tcaggaatta agatctggcc ctcgcagaca gctgaatttt    420

gattctcctg ctgacaataa agacagaaat gccagcaatg atgggtttga aatgtgcagt    480

ttatcagatt tctctgcaaa tgaacagaag tccacttacc taaaagtgct agaacacatg    540

ctaccagatg attcccagta ccatacaaaa acaggaattc tgaatgccac agctggtgat    600

tcctatgtgc aaacagaaat cagcacttca ctcttttcac caaattacct ttctgcaata    660

ctgggggatt gtgatattcc cattattcaa agaatctctc atgtttcagg gtataactat    720

ggaatccctc attcttgtat caggtaataa attttatctt tctttctttt gagggaaagt    780

agcctcaggc aagggcaggc ctctccttca tgtccagcag acagcatcta ctccttattt    840

atagtaaatg aatataacag aaattatcat gaacagcatt tgcatcaata ataggaatac    900

ctggatgtgg gaaaattaat gagaaattgg gactttctag gtgggagaaa gatgatattg    960

ttcatgtaca tcagaacagc tgctacttgc caggatctgt agcagatctg tttctattgt   1020

ttattatagc gtaacatgat acatctagta catctgtgaa agtgaaatag ttaacccttc   1080

tacagtggag aaaaaaatta cacaatccac aggacttttt taaggttatc aaattcactt   1140

aacccaacca ggagacttaa agatgctttg ttaaaaaaca agggcatgta gtttaattaa   1200

gtaggtcttt ggggcagtta gttcacctac acacattgaa atatgatcct aattttgagt   1260

gctttctaca atttcaaccc cggaaaaaac agataatttt ggtgattaca aacagtaaga   1320

cattgttggt ggagatgaga gtttgagagt cagggtgaca ataagttatt ttcacctagt   1380

gcttcgagtt agaatttgaa ataaggtccc taagaggtga aataacaagt aatccctagt   1440

actaacaatg gtataatagg aaatatgttc ttttaatctt gt                      1482


<210>  6043
<211>  208
<212>  PRT
<213>  Homo sapiens

<400>  6043

Met Ala Ser Trp Leu Tyr Glu Cys Leu Cys Glu Ala Glu Leu Ala Gln 
1               5                   10                  15


Tyr Tyr Ser His Phe Thr Ala Leu Gly Leu Gln Lys Ile Asp Glu Leu 
            20                  25                  30


Ala Lys Ile Thr Met Lys Asp Tyr Ser Lys Leu Gly Val His Asp Met 
        35                  40                  45


Asn Asp Arg Lys Arg Leu Phe Gln Leu Ile Lys Ile Ile Lys Ile Met 
    50                  55                  60


Gln Glu Glu Asp Lys Ala Val Ser Ile Pro Glu Arg His Leu Gln Thr 
65                  70                  75                  80


Ser Ser Leu Arg Ile Lys Ser Gln Glu Leu Arg Ser Gly Pro Arg Arg 
                85                  90                  95


Gln Leu Asn Phe Asp Ser Pro Ala Asp Asn Lys Asp Arg Asn Ala Ser 
            100                 105                 110


Asn Asp Gly Phe Glu Met Cys Ser Leu Ser Asp Phe Ser Ala Asn Glu 
        115                 120                 125


Gln Lys Ser Thr Tyr Leu Lys Val Leu Glu His Met Leu Pro Asp Asp 
    130                 135                 140


Ser Gln Tyr His Thr Lys Thr Gly Ile Leu Asn Ala Thr Ala Gly Asp 
145                 150                 155                 160


Ser Tyr Val Gln Thr Glu Ile Ser Thr Ser Leu Phe Ser Pro Asn Tyr 
                165                 170                 175


Leu Ser Ala Ile Leu Gly Asp Cys Asp Ile Pro Ile Ile Gln Arg Ile 
            180                 185                 190


Ser His Val Ser Gly Tyr Asn Tyr Gly Ile Pro His Ser Cys Ile Arg 
        195                 200                 205


<210>  6044
<211>  1175
<212>  DNA
<213>  Homo sapiens

<400>  6044
gagatgcggc ctggccgccg ccggtggctc ccgggttgac gggactgtta ggttgcgggc     60

tttggggctc actcccgacg gcattgtctt ctcctcttct cagacagggc agaccgagga    120

gtttggaccg aggccggacc aggtgcccag tgaacagcag ggagccgctc tgggtgtccc    180

acaccaggaa gatgaagggg tggtcggagt agaacagctt ggggctgcgc agctccttgc    240

tcccatagat gtcctggtca aaggagttgc cgtctgtgtc caactcaaag gcggtggcgt    300

ggaacacgct ggtcagagtt tatagaaacc tattcaccaa aatggcatcc tggttatatg    360

aatgtctttg tgaagctgaa cttgcacagt attattctca tttcactgcc cttggccttc    420

agaaaataga tgaattagcc aagattacaa tgaaggacta ctccaaatta ggagtccatg    480

acatgaacga ccgcaaacgt ctcttccaac ttatcaaaat tattaagatt atgcaagaag    540

aagataaagc agtcagtatc ccagagcgtc atcttcagac aagcagcctg cgcatcaaat    600

ctcaggaatt aagatctggc cctcgcagac agctgaattt tgattctcct gctgacaata    660

aagacagaaa tgccagcaat gatgggtttg aaatgtgcag tttatcagat ttctctgcaa    720

atgaacagaa gtccacttac ctaaaagtgc tagaacacat gctaccagat gattcccagt    780

accatacaaa aacaggaatt ctgaatgcca cagctggtga ttcctatgtg caaacagaaa    840

tcagcacttc actcttttca ccaaattacc tttctgcaat actgggggat tgtgatattc    900

ccattattca aagaatctct catgtttcag ggtataacta tggaatccct cattcttgta    960

tcaggtaata aattttatct ttctttcttt tgagggaaag tagcctcagg caagggcagg   1020

cctctccttc atgtccagca gacagcatct actccttatt tatagtaaat gaatataaca   1080

gaaattatca tgaacagcat ttgcatcaat aataggaata cctggatgtg ggaaaattaa   1140

tgagaaattg ggactttcta ggtgggagaa agatg                              1175


<210>  6045
<211>  239
<212>  PRT
<213>  Homo sapiens

<400>  6045

Met Ser Trp Ser Lys Glu Leu Pro Ser Val Ser Asn Ser Lys Ala Val 
1               5                   10                  15


Ala Trp Asn Thr Leu Val Arg Val Tyr Arg Asn Leu Phe Thr Lys Met 
            20                  25                  30


Ala Ser Trp Leu Tyr Glu Cys Leu Cys Glu Ala Glu Leu Ala Gln Tyr 
        35                  40                  45


Tyr Ser His Phe Thr Ala Leu Gly Leu Gln Lys Ile Asp Glu Leu Ala 
    50                  55                  60


Lys Ile Thr Met Lys Asp Tyr Ser Lys Leu Gly Val His Asp Met Asn 
65                  70                  75                  80


Asp Arg Lys Arg Leu Phe Gln Leu Ile Lys Ile Ile Lys Ile Met Gln 
                85                  90                  95


Glu Glu Asp Lys Ala Val Ser Ile Pro Glu Arg His Leu Gln Thr Ser 
            100                 105                 110


Ser Leu Arg Ile Lys Ser Gln Glu Leu Arg Ser Gly Pro Arg Arg Gln 
        115                 120                 125


Leu Asn Phe Asp Ser Pro Ala Asp Asn Lys Asp Arg Asn Ala Ser Asn 
    130                 135                 140


Asp Gly Phe Glu Met Cys Ser Leu Ser Asp Phe Ser Ala Asn Glu Gln 
145                 150                 155                 160


Lys Ser Thr Tyr Leu Lys Val Leu Glu His Met Leu Pro Asp Asp Ser 
                165                 170                 175


Gln Tyr His Thr Lys Thr Gly Ile Leu Asn Ala Thr Ala Gly Asp Ser 
            180                 185                 190


Tyr Val Gln Thr Glu Ile Ser Thr Ser Leu Phe Ser Pro Asn Tyr Leu 
        195                 200                 205


Ser Ala Ile Leu Gly Asp Cys Asp Ile Pro Ile Ile Gln Arg Ile Ser 
    210                 215                 220


His Val Ser Gly Tyr Asn Tyr Gly Ile Pro His Ser Cys Ile Arg 
225                 230                 235


<210>  6046
<211>  962
<212>  DNA
<213>  Homo sapiens

<400>  6046
ctattgatgg gcccaagcgt aaccaggctc ttctgattgg ccggtgtact tcagtttccg     60

tccaaggtcc gcctcctacc tccttctgct tcggtgcgtt tgcttctgag gatctccagt    120

gtcacaacaa acacatgcca gccctgtttt acagggagcc ctggaggagt tgggatagag    180

gccacattga ctgagggtag ttgccagggt cctgcagtta tacacaaagt ccttaggata    240

agaccatggc cttgagagca tgtggcttga tcatcttccg aagatgcctc attcccaaag    300

tggacaacaa tgcaattgag tttttactgc tgcaggcatc agatggcatt catcactgga    360

ctcctcccaa aggccatgtg gaaccaggag aggatgactt ggaaacagcc ctgagggaga    420

cccaagagga agcaggcata gaagcaggcc agctgaccat tattgagggg ttcaaaaggg    480

aactcaatta tgtggccagg aacaagccta aaacagtcat ttactggctg gcggaggtga    540

aggactatga cgtggagatc cgcctctccc atgagcacca agcctaccgc tggctggggc    600

tggaggaggc ctgccagttg gctcagttca aggagatgaa ggcagcgctc caagaaggac    660

accagtttct ttgctccata gaggcctgag ctgactggag cagagtcatt tgcttcagca    720

ggatccttgt gggccttcta agatgaagcc accctcaggt ccagggaagg ttgtgctggt    780

atttggctca tgacagccaa gagcagattt gtgaaatcgg ctcaactccc aggtgagagc    840

aagcaaaaat cttggctggg tggaaaggaa ggcaaaagag taaaaattaa aaaggccagg    900

cccagtaagt gtaccttgta ctttataaat aaacctcaag cagctcaagg ttgtccttct    960

aa                                                                   962


<210>  6047
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6047

Met Ala Leu Arg Ala Cys Gly Leu Ile Ile Phe Arg Arg Cys Leu Ile 
1               5                   10                  15


Pro Lys Val Asp Asn Asn Ala Ile Glu Phe Leu Leu Leu Gln Ala Ser 
            20                  25                  30


Asp Gly Ile His His Trp Thr Pro Pro Lys Gly His Val Glu Pro Gly 
        35                  40                  45


Glu Asp Asp Leu Glu Thr Ala Leu Arg Glu Thr Gln Glu Glu Ala Gly 
    50                  55                  60


Ile Glu Ala Gly Gln Leu Thr Ile Ile Glu Gly Phe Lys Arg Glu Leu 
65                  70                  75                  80


Asn Tyr Val Ala Arg Asn Lys Pro Lys Thr Val Ile Tyr Trp Leu Ala 
                85                  90                  95


Glu Val Lys Asp Tyr Asp Val Glu Ile Arg Leu Ser His Glu His Gln 
            100                 105                 110


Ala Tyr Arg Trp Leu Gly Leu Glu Glu Ala Cys Gln Leu Ala Gln Phe 
        115                 120                 125


Lys Glu Met Lys Ala Ala Leu Gln Glu Gly His Gln Phe Leu Cys Ser 
    130                 135                 140


Ile Glu Ala 
145


<210>  6048
<211>  1004
<212>  DNA
<213>  Homo sapiens

<400>  6048
ctattgatgg gcccaagcgt aaccaggctc ttctgattgg ccggtgtact tcagtttccg     60

tccaaggtcc gcctcctacc tccttctgct tcggttctac agtgatgggg tgcttccttt    120

tggcttctgg aatgggtgcg tttgcttctg aggatctcca gtgtcacaac aaacacatgc    180

cagccctgtt ttacagggag ccctggagga gttgggatag aggccacatt gactgagggt    240

agttgccagg gtcctgcagt tatacacaaa gtccttagga taagaccatg gccttgagag    300

catgtggctt gatcatcttc cgaagatgcc tcattcccaa agtggacaac aatgcaattg    360

agtttttact gctgcaggca tcagatggca ttcatcactg gactcctccc aaaggccatg    420

tggaaccagg agaggatgac ttggaaacag ccctgaggga gacccaagag gaagcaggca    480

tagaagcagg ccagctgacc attattgagg ggttcaaaag ggaactcaat tatgtggcca    540

ggaacaagcc taaaacagtc atttactggc tggcggaggt gaaggactat gacgtggaga    600

tccgcctctc ccatgagcac caagcctacc gctggctggg gctggaggag gcctgccagt    660

tggctcagtt caaggagatg aaggcagcgc tccaagaagg acaccagttt ctttgctcca    720

tagaggcctg agctgactgg agcagagtca tttgcttcag caggatcctt gtgggccttc    780

taagatgaag ccaccctcag gtccagggaa ggttgtgctg gtatttggct catgacagcc    840

aagagcagat ttgtgaaatc ggctcaactc ccaggtgaga gcaagcaaaa atcttggctg    900

ggtggaaagg aaggcaaaag agtaaaaatt aaaaaggcca ggcccagtaa gtgtaccttg    960

tactttataa ataaacctca agcagctcaa ggttgtcctt ctaa                    1004


<210>  6049
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6049

Met Ala Leu Arg Ala Cys Gly Leu Ile Ile Phe Arg Arg Cys Leu Ile 
1               5                   10                  15


Pro Lys Val Asp Asn Asn Ala Ile Glu Phe Leu Leu Leu Gln Ala Ser 
            20                  25                  30


Asp Gly Ile His His Trp Thr Pro Pro Lys Gly His Val Glu Pro Gly 
        35                  40                  45


Glu Asp Asp Leu Glu Thr Ala Leu Arg Glu Thr Gln Glu Glu Ala Gly 
    50                  55                  60


Ile Glu Ala Gly Gln Leu Thr Ile Ile Glu Gly Phe Lys Arg Glu Leu 
65                  70                  75                  80


Asn Tyr Val Ala Arg Asn Lys Pro Lys Thr Val Ile Tyr Trp Leu Ala 
                85                  90                  95


Glu Val Lys Asp Tyr Asp Val Glu Ile Arg Leu Ser His Glu His Gln 
            100                 105                 110


Ala Tyr Arg Trp Leu Gly Leu Glu Glu Ala Cys Gln Leu Ala Gln Phe 
        115                 120                 125


Lys Glu Met Lys Ala Ala Leu Gln Glu Gly His Gln Phe Leu Cys Ser 
    130                 135                 140


Ile Glu Ala 
145


<210>  6050
<211>  1075
<212>  DNA
<213>  Homo sapiens

<400>  6050
ctattgatgg gcccaagcgt aaccaggctc ttctgattgg ccggtgtact tcagtttccg     60

tccaaggtcc gcctcctacc tccttctgct tcggggaggg catgggatca gctacctgtt    120

tctgcctcaa ccacggacca ataatatgag atctttgttc accagttcta cagtgatggg    180

gtgcttcctt ttggcttctg gaatgggtgc gtttgcttct gaggatctcc agtgtcacaa    240

caaacacatg ccagccctgt tttacaggga gccctggagg agttgggata gaggccacat    300

tgactgaggg tagttgccag ggtcctgcag ttatacacaa agtccttagg ataagaccat    360

ggccttgaga gcatgtggct tgatcatctt ccgaagatgc ctcattccca aagtggacaa    420

caatgcaatt gagtttttac tgctgcaggc atcagatggc attcatcact ggactcctcc    480

caaaggccat gtggaaccag gagaggatga cttggaaaca gccctgaggg agacccaaga    540

ggaagcaggc atagaagcag gccagctgac cattattgag gggttcaaaa gggaactcaa    600

ttatgtggcc aggaacaagc ctaaaacagt catttactgg ctggcggagg tgaaggacta    660

tgacgtggag atccgcctct cccatgagca ccaagcctac cgctggctgg ggctggagga    720

ggcctgccag ttggctcagt tcaaggagat gaaggcagcg ctccaagaag gacaccagtt    780

tctttgctcc atagaggcct gagctgactg gagcagagtc atttgcttca gcaggatcct    840

tgtgggcctt ctaagatgaa gccaccctca ggtccaggga aggttgtgct ggtatttggc    900

tcatgacagc caagagcaga tttgtgaaat cggctcaact cccaggtgag agcaagcaaa    960

aatcttggct gggtggaaag gaaggcaaaa gagtaaaaat taaaaaggcc aggcccagta   1020

agtgtacctt gtactttata aataaacctc aagcagctca aggttgtcct tctaa        1075


<210>  6051
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6051

Met Ala Leu Arg Ala Cys Gly Leu Ile Ile Phe Arg Arg Cys Leu Ile 
1               5                   10                  15


Pro Lys Val Asp Asn Asn Ala Ile Glu Phe Leu Leu Leu Gln Ala Ser 
            20                  25                  30


Asp Gly Ile His His Trp Thr Pro Pro Lys Gly His Val Glu Pro Gly 
        35                  40                  45


Glu Asp Asp Leu Glu Thr Ala Leu Arg Glu Thr Gln Glu Glu Ala Gly 
    50                  55                  60


Ile Glu Ala Gly Gln Leu Thr Ile Ile Glu Gly Phe Lys Arg Glu Leu 
65                  70                  75                  80


Asn Tyr Val Ala Arg Asn Lys Pro Lys Thr Val Ile Tyr Trp Leu Ala 
                85                  90                  95


Glu Val Lys Asp Tyr Asp Val Glu Ile Arg Leu Ser His Glu His Gln 
            100                 105                 110


Ala Tyr Arg Trp Leu Gly Leu Glu Glu Ala Cys Gln Leu Ala Gln Phe 
        115                 120                 125


Lys Glu Met Lys Ala Ala Leu Gln Glu Gly His Gln Phe Leu Cys Ser 
    130                 135                 140


Ile Glu Ala 
145


<210>  6052
<211>  675
<212>  DNA
<213>  Homo sapiens

<400>  6052
ggcccaagcg taaccaggct cttctgattg gccggtgtac ttcagtttcc gtccaaggtc     60

cgcctcctac ctccttctgc ttcgggccat gtggaaccag gagaggatga cttggaaaca    120

gccctgaggg agacccaaga ggaagcaggc atagaagcag gccagctgac cattattgag    180

gggttcaaaa gggaactcaa ttatgtggcc aggaacaagc ctaaaacagt catttactgg    240

ctggcggagg tgaaggacta tgacgtggag atccgcctct cccatgagca ccaagcctac    300

cgctggctgg ggctggagga ggcctgccag ttggctcagt tcaaggagat gaaggcagcg    360

ctccaagaag gacaccagtt tctttgctcc atagaggcct gagctgactg gagcagagtc    420

atttgcttca gcaggatcct tgtgggcctt ctaagatgaa gccaccctca ggtccaggga    480

aggttgtgct ggtatttggc tcatgacagc caagagcaga tttgtgaaat cggctcaact    540

cccaggtgag agcaagcaaa aatcttggct gggtggaaag gaaggcaaaa gagtaaaaat    600

taaaaaggcc aggcccagta agtgtacctt gtactttata aataaacctc aagcagctca    660

aggttgtcct tctaa                                                     675


<210>  6053
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  6053

Met Thr Ala Lys Ser Arg Phe Val Lys Ser Ala Gln Leu Pro Gly Glu 
1               5                   10                  15


Ser Lys Gln Lys Ser Trp Leu Gly Gly Lys Glu Gly Lys Arg Val Lys 
            20                  25                  30


Ile Lys Lys Ala Arg Pro Ser Lys Cys Thr Leu Tyr Phe Ile Asn Lys 
        35                  40                  45


Pro Gln Ala Ala Gln Gly Cys Pro 
    50                  55


<210>  6054
<211>  766
<212>  DNA
<213>  Homo sapiens

<400>  6054
ccaaggtccg cctcctacct ccttctgctt cggtccttag gataagacca tggccttgag     60

agcatgtggc ttgatcatct tccgaagatg cctcattccc aaagtggaca acaatgcaat    120

tgagttttta ctgctgcagg catcagatgg cattcatcac tggactcctc ccaaaggcca    180

tgtggaacca ggagaggatg acttggaaac agccctgagg gagacccaag aggaagcagg    240

catagaagca ggccagctga ccattattga ggggttcaaa agggaactca attatgtggc    300

caggaacaag cctaaaacag tcatttactg gctggcggag gtgaaggact atgacgtgga    360

gatccgcctc tcccatgagc accaagccta ccgctggctg gggctggagg aggcctgcca    420

gttggctcag ttcaaggaga tgaaggcagc gctccaagaa ggacaccagt ttctttgctc    480

catagaggcc tgagctgact ggagcagagt catttgcttc agcaggatcc ttgtgggcct    540

tctaagatga agccaccctc aggtccaggg aaggttgtgc tggtatttgg ctcatgacag    600

ccaagagcag atttgtgaaa tcggctcaac tcccaggtga gagcaagcaa aaatcttggc    660

tgggtggaaa ggaaggcaaa agagtaaaaa ttaaaaaggc caggcccagt aagtgtacct    720

tgtactttat aaataaacct caagcagctc aaggttgtcc ttctaa                   766


<210>  6055
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6055

Met Ala Leu Arg Ala Cys Gly Leu Ile Ile Phe Arg Arg Cys Leu Ile 
1               5                   10                  15


Pro Lys Val Asp Asn Asn Ala Ile Glu Phe Leu Leu Leu Gln Ala Ser 
            20                  25                  30


Asp Gly Ile His His Trp Thr Pro Pro Lys Gly His Val Glu Pro Gly 
        35                  40                  45


Glu Asp Asp Leu Glu Thr Ala Leu Arg Glu Thr Gln Glu Glu Ala Gly 
    50                  55                  60


Ile Glu Ala Gly Gln Leu Thr Ile Ile Glu Gly Phe Lys Arg Glu Leu 
65                  70                  75                  80


Asn Tyr Val Ala Arg Asn Lys Pro Lys Thr Val Ile Tyr Trp Leu Ala 
                85                  90                  95


Glu Val Lys Asp Tyr Asp Val Glu Ile Arg Leu Ser His Glu His Gln 
            100                 105                 110


Ala Tyr Arg Trp Leu Gly Leu Glu Glu Ala Cys Gln Leu Ala Gln Phe 
        115                 120                 125


Lys Glu Met Lys Ala Ala Leu Gln Glu Gly His Gln Phe Leu Cys Ser 
    130                 135                 140


Ile Glu Ala 
145


<210>  6056
<211>  544
<212>  DNA
<213>  Homo sapiens

<400>  6056
gtgcgtttgc ttctgaggat ctccagtgtc acaacaaaca catgcccagc taattttttt     60

ttttttttgt atttttagta gagatggggt ttcaccgtgt tagccaggat ggtctcaatc    120

tcctgacctc gtgatccacc cacctcggcc tcccaaagtg ctgggattgc aggtgtgagc    180

caccgcgccc ggctgtaagt tgtattcttt gcaggaataa ctgacagtag ggtgggacta    240

aagcatgtta tgggaggtgg atgagggtgg gagagagagg agctgagatt aggatgtggc    300

aggtgagtag gctttgacaa catcaccact ttgcttttgg ccagtggggc ttgggcaacc    360

tgaactcaga ccccagagcg ttacaaaatc cagctcccgt gccccaccac acccctctca    420

actggcagag cagcactctg ccgatgctgc actttgggtt aggccaggcc tcagggagac    480

ctcagcagag ttgtaccagt tcaggagatg cttccatgtt gaagttttcc tccagagaat    540

gggg                                                                 544


<210>  6057
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  6057

Met Leu His Phe Gly Leu Gly Gln Ala Ser Gly Arg Pro Gln Gln Ser 
1               5                   10                  15


Cys Thr Ser Ser Gly Asp Ala Ser Met Leu Lys Phe Ser Ser Arg Glu 
            20                  25                  30


<210>  6058
<211>  4203
<212>  DNA
<213>  Homo sapiens

<400>  6058
agacagagcc ccgcgcggcg cggcggcagc ttcactctgg ttcaagcgca ggggatcggc     60

gggaagctct ttcacccccg cttctgccgg gctgtaactg caatggagca ggttgagatg    120

aactcagtca gatggcccca cggcccgctc ctttcttagc agcccactaa tgctccagaa    180

ccctcaggag aagagccagg cctacccccg ccgccgccgg cctggctgct acgcatagcg    240

tcagaacccc gaggccatcg cagccgcagc tatgtacacc ttcctgcccg acaacttctc    300

acctgccaag cccaagcctt ccaaagacct gaagccgctg ctgggctccg cggttctggg    360

gctgctgctt gtgctggccg cggtggtggc ctggtgctac tacagcgtct ccctacgcaa    420

ggcggagcga cttcgcgcgg agctgctgga cctgaaagct ggcggcttct ccatccgcaa    480

tcagaaggga gagcaggtct tccgcctggc cttccgctcc ggcgcgctgg accttgactc    540

ctgcagccgc gatggcgccc tgctgggctg ctcgctcacg gccgacgggc tgccgctgca    600

cttcttcatc cagactgtgc ggcccaagga cacggtcatg tgctaccgcg tgcgctggga    660

ggaggcagcg ccgggccggg ccgtggagca cgccatgttc ttgggcgacg cggcggccca    720

ctggtatggt ggcgccgaga tgaggacgca acactggccc atccgcctgg atggccagca    780

ggagccccag ccgttcgtca ccagcgatgt ctactcctcc gacgccgcgt ttgggggcat    840

cctcgagcgc tactggctat cttcgcgcgc ggccgccatc aaagtcaatg actcagtgcc    900

cttccacctg ggctggaaca gcacggagcg ctcgctgcgg cttcaggcgc gctaccacga    960

cacgccctac aagccacccg ccggccgcgc cgcagcgcca gagctgagct accgagtgtg   1020

cgtgggctca gacgtcacct ccatccacaa gtacatggtg cgtcgctact tcaacaagcc   1080

gtcaagggtg ccagcacccg aggccttccg agaccccatt tggtccacat gggcgctgta   1140

cgggcgcgcc gtggaccagg acaaggtgct gcgttttgcc caacagatcc gcctgcacca   1200

cttcaacagc agccacctgg aaatcgacga catgtacaca cctgcttatg gcgacttcga   1260

cttcgatgag gtcaaattcc ccaacgccag cgacatgttc cgccgcctgc gcgacgccgg   1320

cttccgcgtc acgctctggg tgcacccttt tgtcaactac aactcgtcgc gcttcggcga   1380

gggcgtggag cgcgagctgt tcgtgcgcga acccacgggc cggttacctg cgctggtgcg   1440

ctggtggaac ggcatcggcg cggtgctaga cttcacgcac ccaaaggccc gcgactggtt   1500

ccagggacac ctgcggcggc tgcgctctcg ctactccgtg gcttccttca agttcgacgc   1560

gggcgaggtc agctacctgc cgcgggactt cagcacctac cggccgctgc cggaccccag   1620

cgtctggagc cggcgctaca ctgagatggc gctgcccttc ttctcgctgg cggaggtgcg   1680

cgtaggctac cagtcacaga acatctcctg cttcttccgc ctggtggatc gcgactctgt   1740

gtggggctac gacctggggt tgcgctcact catccccgcg gtgctcaccg tcagcatgct   1800

gggctaccca ttcatcctac ccgatatggt gggcggcaac gccgtgcccc agcggacagc   1860

cggcggcgat gtgcccgagc gcgagctcta cattcgctgg ctggaagtgg ccgcctttat   1920

gccggccatg cagttctcta tcccgccctg gcgctacgac gcggaagtgg tggccatcgc   1980

gcagaagttc gccgccctgc gggcctcgct tgtggcaccg ctgttgcttg agctggcggg   2040

cgaggtcacc gacacgggtg accctatcgt gcgccccctt tggtggattg cgcccggcga   2100

cgagacagct caccgtatcg actcgcagtt ccttattggg gacacgctgc ttgtggcccc   2160

ggtgctggag ccaggcaagc aggagcgcga cgtctatttg cccgccggca agtggcgcag   2220

ctacaagggt gagcttttcg acaagacgcc ggtgctgctc accgattacc cggtcgacct   2280

ggatgagatc gcctacttta cctgggcgtc ctgacccagc ccagggcccg gtaaccgcaa   2340

agcccccagt cttcatgcag accttgaacc ctccgtcaca cccgcaccat gtactcccag   2400

gaacctccca cctctatacc acccattaag tggctgctga cttaaatgtg ctggaaccag   2460

ctgctgaagg tggggcctag ggagggggca ctgaagcaat ctcctgctcc aacgcacaat   2520

ccttactgtg ccctttccac ccccacactc acaccaatct gcagaaacct cttccctggg   2580

gtggaagcca gagagcttag aggaaaaagg tcagctctct tcctgttata catggttata   2640

catggttggg gtttaaaagc acaaagagaa acctccccct cctggctttc gtggccatct   2700

ttgtccatct taggtgggga cttgatctta tttaaggtct ccaaatagcc cccaccacac   2760

ttagaacgtg tgttttctta gtgttagaag ccaggccctg agtccccagc actcacctga   2820

actgtggctg atttggtccc agtccagctg gggaggtgtt tggctgacaa ggaggcaaga   2880

gatcccctcc cagggaacag gaggactggg cttagcacag agccatcatc atgttcccaa   2940

tttgtgaaga gactcctaac actgcactaa cccatttgtg tacatacatg ggctcagccc   3000

tgggccaaat gtgcctgatg ggaacagact tgcagggcca tgcaggccag acttcgtgcc   3060

ttaactgaag agtgtgcgtg tgtgtgtgtg agagagagag agagagagaa acacgcatca   3120

tgggtccctg atctatgaaa tgaacacaac ctctctgagg ctggatgatc tggaggaagg   3180

gggcatggag caaatttgag gctctgattg ctgagccagc ctcctcccag gcggtttccc   3240

caggactctc gtaggaaata aatagccctt tcaagattcc tcagctgcct caccccctgc   3300

acatgtgcct ggggtgtggc ctagaaggga gtgatgttct tactctggtg gtctgtgctt   3360

ctgaacacag gctacatgca cacactgaca actaccaata aacagacagg ggaaggtctt   3420

tcatctcagc cattttctct tccccccgcc cccccttaga tggagtcttg ctctgtcacc   3480

caggttggag tgcagtggca caatcagctc actgcaaccc ctcctcctag gttcaagcga   3540

ttgagtagct gagattacag gcatgcatca ctatgcctgg ctttttgtat tttttagtag   3600

agatggggtt taccatgttg gccaggctag tctcaaactc ctgacctagt gatgcaccca   3660

ccttggcctc ccaaagtgtt gggattacag gcatgagcca ccacgccagc cattttctct   3720

ttctaagaag agcaacctca gccggagtga gttttttctg actttgcagc tgagtctgga   3780

gaaaagtggc atgccagagc gggtcggtgg gaaacagggt gaactttagc ttccatcaac   3840

agctctggta gcaaaaccag tcccctaccc cctagagaat gcatccgttt ccccacctga   3900

tatggtttgg ctgtgtcccc acctaaaact catcttgaat tgtagctccc ataattgcca   3960

tgtgttgtgg gaaggaccca gtgggagata attgaaatat gggggcagtt tccgccatac   4020

tgttctggtg atagtgaata gatctcatga gagctgatga ttttataaga ggtttcccct   4080

tttgcttagt tctcattctc tcttgcctgc cgccatgtaa gacgtgcctt tctgtcatgc   4140

ttgtgaggcc tccccagcca cgtggagctg tgagttcatt aaacctcttt ttctttataa   4200

att                                                                 4203


<210>  6059
<211>  680
<212>  PRT
<213>  Homo sapiens

<400>  6059

Met Tyr Thr Phe Leu Pro Asp Asn Phe Ser Pro Ala Lys Pro Lys Pro 
1               5                   10                  15


Ser Lys Asp Leu Lys Pro Leu Leu Gly Ser Ala Val Leu Gly Leu Leu 
            20                  25                  30


Leu Val Leu Ala Ala Val Val Ala Trp Cys Tyr Tyr Ser Val Ser Leu 
        35                  40                  45


Arg Lys Ala Glu Arg Leu Arg Ala Glu Leu Leu Asp Leu Lys Ala Gly 
    50                  55                  60


Gly Phe Ser Ile Arg Asn Gln Lys Gly Glu Gln Val Phe Arg Leu Ala 
65                  70                  75                  80


Phe Arg Ser Gly Ala Leu Asp Leu Asp Ser Cys Ser Arg Asp Gly Ala 
                85                  90                  95


Leu Leu Gly Cys Ser Leu Thr Ala Asp Gly Leu Pro Leu His Phe Phe 
            100                 105                 110


Ile Gln Thr Val Arg Pro Lys Asp Thr Val Met Cys Tyr Arg Val Arg 
        115                 120                 125


Trp Glu Glu Ala Ala Pro Gly Arg Ala Val Glu His Ala Met Phe Leu 
    130                 135                 140


Gly Asp Ala Ala Ala His Trp Tyr Gly Gly Ala Glu Met Arg Thr Gln 
145                 150                 155                 160


His Trp Pro Ile Arg Leu Asp Gly Gln Gln Glu Pro Gln Pro Phe Val 
                165                 170                 175


Thr Ser Asp Val Tyr Ser Ser Asp Ala Ala Phe Gly Gly Ile Leu Glu 
            180                 185                 190


Arg Tyr Trp Leu Ser Ser Arg Ala Ala Ala Ile Lys Val Asn Asp Ser 
        195                 200                 205


Val Pro Phe His Leu Gly Trp Asn Ser Thr Glu Arg Ser Leu Arg Leu 
    210                 215                 220


Gln Ala Arg Tyr His Asp Thr Pro Tyr Lys Pro Pro Ala Gly Arg Ala 
225                 230                 235                 240


Ala Ala Pro Glu Leu Ser Tyr Arg Val Cys Val Gly Ser Asp Val Thr 
                245                 250                 255


Ser Ile His Lys Tyr Met Val Arg Arg Tyr Phe Asn Lys Pro Ser Arg 
            260                 265                 270


Val Pro Ala Pro Glu Ala Phe Arg Asp Pro Ile Trp Ser Thr Trp Ala 
        275                 280                 285


Leu Tyr Gly Arg Ala Val Asp Gln Asp Lys Val Leu Arg Phe Ala Gln 
    290                 295                 300


Gln Ile Arg Leu His His Phe Asn Ser Ser His Leu Glu Ile Asp Asp 
305                 310                 315                 320


Met Tyr Thr Pro Ala Tyr Gly Asp Phe Asp Phe Asp Glu Val Lys Phe 
                325                 330                 335


Pro Asn Ala Ser Asp Met Phe Arg Arg Leu Arg Asp Ala Gly Phe Arg 
            340                 345                 350


Val Thr Leu Trp Val His Pro Phe Val Asn Tyr Asn Ser Ser Arg Phe 
        355                 360                 365


Gly Glu Gly Val Glu Arg Glu Leu Phe Val Arg Glu Pro Thr Gly Arg 
    370                 375                 380


Leu Pro Ala Leu Val Arg Trp Trp Asn Gly Ile Gly Ala Val Leu Asp 
385                 390                 395                 400


Phe Thr His Pro Lys Ala Arg Asp Trp Phe Gln Gly His Leu Arg Arg 
                405                 410                 415


Leu Arg Ser Arg Tyr Ser Val Ala Ser Phe Lys Phe Asp Ala Gly Glu 
            420                 425                 430


Val Ser Tyr Leu Pro Arg Asp Phe Ser Thr Tyr Arg Pro Leu Pro Asp 
        435                 440                 445


Pro Ser Val Trp Ser Arg Arg Tyr Thr Glu Met Ala Leu Pro Phe Phe 
    450                 455                 460


Ser Leu Ala Glu Val Arg Val Gly Tyr Gln Ser Gln Asn Ile Ser Cys 
465                 470                 475                 480


Phe Phe Arg Leu Val Asp Arg Asp Ser Val Trp Gly Tyr Asp Leu Gly 
                485                 490                 495


Leu Arg Ser Leu Ile Pro Ala Val Leu Thr Val Ser Met Leu Gly Tyr 
            500                 505                 510


Pro Phe Ile Leu Pro Asp Met Val Gly Gly Asn Ala Val Pro Gln Arg 
        515                 520                 525


Thr Ala Gly Gly Asp Val Pro Glu Arg Glu Leu Tyr Ile Arg Trp Leu 
    530                 535                 540


Glu Val Ala Ala Phe Met Pro Ala Met Gln Phe Ser Ile Pro Pro Trp 
545                 550                 555                 560


Arg Tyr Asp Ala Glu Val Val Ala Ile Ala Gln Lys Phe Ala Ala Leu 
                565                 570                 575


Arg Ala Ser Leu Val Ala Pro Leu Leu Leu Glu Leu Ala Gly Glu Val 
            580                 585                 590


Thr Asp Thr Gly Asp Pro Ile Val Arg Pro Leu Trp Trp Ile Ala Pro 
        595                 600                 605


Gly Asp Glu Thr Ala His Arg Ile Asp Ser Gln Phe Leu Ile Gly Asp 
    610                 615                 620


Thr Leu Leu Val Ala Pro Val Leu Glu Pro Gly Lys Gln Glu Arg Asp 
625                 630                 635                 640


Val Tyr Leu Pro Ala Gly Lys Trp Arg Ser Tyr Lys Gly Glu Leu Phe 
                645                 650                 655


Asp Lys Thr Pro Val Leu Leu Thr Asp Tyr Pro Val Asp Leu Asp Glu 
            660                 665                 670


Ile Ala Tyr Phe Thr Trp Ala Ser 
        675                 680


<210>  6060
<211>  591
<212>  DNA
<213>  Homo sapiens

<400>  6060
gctgaagggc gggagaagtt gcggcgtggc gataggaggc caggatggag acagcagttc     60

gaggaatgcc cttggaatgc cctcctaggc cggagcggct caatgcctac gagcgcgaag    120

tgatggtgaa catgctgaac tcactgtcgc ggaaccagca gctgccgcgg atcacgcccc    180

gatgcgggtg cgtggacccg ctgcccggcc gcctgccctt ccatggttac gaaagtgctt    240

gctcgggccg ccactactgt ctgcgcggga tggactacta cgccagcggg gcgccctgca    300

ccgaccgccg cctgcggcct tggtgccggg agcaaccgac tatgtgtacc tccctacgag    360

caccggcccg gaatgcagtg tgctgttaca actcccccgc cgtcatacta cccatatccg    420

aaccttagat gggacacaag tcacttcaag aagtctggtg gtccccagag aaacaactat    480

gttatccatc ctgagtttgt gtctgagacc tatcccgact atcgttgctg gtagagcctg    540

ggcttgctgt gccaaggggg cagagcaata aataaactct tcaaccccaa a             591


<210>  6061
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  6061

Met Arg Val Arg Gly Pro Ala Ala Arg Pro Pro Ala Leu Pro Trp Leu 
1               5                   10                  15


Arg Lys Cys Leu Leu Gly Pro Pro Leu Leu Ser Ala Arg Asp Gly Leu 
            20                  25                  30


Leu Arg Gln Arg Gly Ala Leu His Arg Pro Pro Pro Ala Ala Leu Val 
        35                  40                  45


Pro Gly Ala Thr Asp Tyr Val Tyr Leu Pro Thr Ser Thr Gly Pro Glu 
    50                  55                  60


Cys Ser Val Leu Leu Gln Leu Pro Arg Arg His Thr Thr His Ile Arg 
65                  70                  75                  80


Thr Leu Asp Gly Thr Gln Val Thr Ser Arg Ser Leu Val Val Pro Arg 
                85                  90                  95


Glu Thr Thr Met Leu Ser Ile Leu Ser Leu Cys Leu Arg Pro Ile Pro 
            100                 105                 110


Thr Ile Val Ala Gly Arg Ala Trp Ala Cys Cys Ala Lys Gly Ala Glu 
        115                 120                 125


Gln 



<210>  6062
<211>  712
<212>  DNA
<213>  Homo sapiens

<400>  6062
tgacagccgc caacacagag ccctggagag gtggggagct gctgaagggc gggagaagtt     60

gcggcgtggc gataggtctg ggtgttctgg gaggacccct aaaagggagc agctctgcca    120

ggtcagagct tgaggtagca tgtgtgccgc ttccaggagg ccaggatgga gacagcagtt    180

cgaggaatgc ccttggaatg ccctcctagg ccggagcggc tcaatgccta cgagcgcgaa    240

gtgatggtga acatgctgaa ctcactgtcg cggaaccagc agctgccgcg gatcacgccc    300

cgatgcgggt gcgtggaccc gctgcccggc cgcctgccct tccatggtta cgaaagtgct    360

tgctcgggcc gccactactg tctgcgcggg atggactact acgccagcgg ggcgccctgc    420

accgaccgcc gcctgcggcc ttggtgccgg gagcaaccga ctatgtgtac ctccctacga    480

gcaccggccc ggaatgcagt gtgctgttac aactcccccg ccgtcatact acccatatcc    540

gaaccttaga tgggacacaa gtcacttcaa gaagtctggt ggtccccaga gaaacaacta    600

tgttatccat cctgagtttg tgtctgagac ctatcccgac tatcgttgct ggtagagcct    660

gggcttgctg tgccaagggg gcagagcaat aaataaactc ttcaacccca aa            712


<210>  6063
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  6063

Met Arg Val Arg Gly Pro Ala Ala Arg Pro Pro Ala Leu Pro Trp Leu 
1               5                   10                  15


Arg Lys Cys Leu Leu Gly Pro Pro Leu Leu Ser Ala Arg Asp Gly Leu 
            20                  25                  30


Leu Arg Gln Arg Gly Ala Leu His Arg Pro Pro Pro Ala Ala Leu Val 
        35                  40                  45


Pro Gly Ala Thr Asp Tyr Val Tyr Leu Pro Thr Ser Thr Gly Pro Glu 
    50                  55                  60


Cys Ser Val Leu Leu Gln Leu Pro Arg Arg His Thr Thr His Ile Arg 
65                  70                  75                  80


Thr Leu Asp Gly Thr Gln Val Thr Ser Arg Ser Leu Val Val Pro Arg 
                85                  90                  95


Glu Thr Thr Met Leu Ser Ile Leu Ser Leu Cys Leu Arg Pro Ile Pro 
            100                 105                 110


Thr Ile Val Ala Gly Arg Ala Trp Ala Cys Cys Ala Lys Gly Ala Glu 
        115                 120                 125


Gln 



<210>  6064
<211>  1170
<212>  DNA
<213>  Homo sapiens

<400>  6064
aatgggcagt gcccatcctg gagggggcat cagtgtgggg tgggagcagg aaggctgttg     60

gggaaggaag ctgagagatc ctctgcagga ggggattata gcagctaagg gcacctgcca    120

ggctggaggt gtggcctgtc taggggaagg gtggtcactg atgtccagca ggagcccttg    180

acaggtagag cccaccacgg catctccaag accacaccat gttcctgttc tcccgtaaga    240

ccaggacccc tatcagtacc tacagtgact cctacagggc tcccacctcc atcaaggagg    300

tctataagga cccacccctg tgtgcctggg aagccaacaa gtttctgact ccgggtctga    360

ctcataccat ggagcgacat gtggatcccg aagccctgca gaagatggcc aaatgtgctg    420

tacaggacta cacttatagg gggtccatat caggccaccc ctacttgcct gagaagtact    480

ggctttctca agaggaagca gacaaatgca gcccaaacta cctgggcagt gactggtaca    540

acacatggag gatggaacct tacaacagca gctgctgcaa caagtatacc acctaccttc    600

ctcggctgcc taaggaggcc aggatggaga cagcagttcg aggaatgccc ttggaatgcc    660

ctcctaggcc ggagcggctc aatgcctacg agcgcgaagt gatggtgaac atgctgaact    720

cactgtcgcg gaaccagcag ctgccgcgga tcacgccccg atgcgggtgc gtggacccgc    780

tgcccggccg cctgcccttc catggttacg aaagtgcttg ctcgggccgc cactactgtc    840

tgcgcgggat ggactactac gccagcgggg cgccctgcac cgaccgccgc ctgcggcctt    900

ggtgccggga gcaaccgact atgtgtacct ccctacgagc accggcccgg aatgcagtgt    960

gctgttacaa ctcccccgcc gtcatactac ccatatccga accttagatg ggacacaagt   1020

cacttcaaga agtctggtgg tccccagaga aacaactatg ttatccatcc tgagtttgtg   1080

tctgagacct atcccgacta tcgttgctgg tagagcctgg gcttgctgtg ccaagggggc   1140

agagcaataa ataaactctt caaccccaaa                                    1170


<210>  6065
<211>  262
<212>  PRT
<213>  Homo sapiens

<400>  6065

Met Phe Leu Phe Ser Arg Lys Thr Arg Thr Pro Ile Ser Thr Tyr Ser 
1               5                   10                  15


Asp Ser Tyr Arg Ala Pro Thr Ser Ile Lys Glu Val Tyr Lys Asp Pro 
            20                  25                  30


Pro Leu Cys Ala Trp Glu Ala Asn Lys Phe Leu Thr Pro Gly Leu Thr 
        35                  40                  45


His Thr Met Glu Arg His Val Asp Pro Glu Ala Leu Gln Lys Met Ala 
    50                  55                  60


Lys Cys Ala Val Gln Asp Tyr Thr Tyr Arg Gly Ser Ile Ser Gly His 
65                  70                  75                  80


Pro Tyr Leu Pro Glu Lys Tyr Trp Leu Ser Gln Glu Glu Ala Asp Lys 
                85                  90                  95


Cys Ser Pro Asn Tyr Leu Gly Ser Asp Trp Tyr Asn Thr Trp Arg Met 
            100                 105                 110


Glu Pro Tyr Asn Ser Ser Cys Cys Asn Lys Tyr Thr Thr Tyr Leu Pro 
        115                 120                 125


Arg Leu Pro Lys Glu Ala Arg Met Glu Thr Ala Val Arg Gly Met Pro 
    130                 135                 140


Leu Glu Cys Pro Pro Arg Pro Glu Arg Leu Asn Ala Tyr Glu Arg Glu 
145                 150                 155                 160


Val Met Val Asn Met Leu Asn Ser Leu Ser Arg Asn Gln Gln Leu Pro 
                165                 170                 175


Arg Ile Thr Pro Arg Cys Gly Cys Val Asp Pro Leu Pro Gly Arg Leu 
            180                 185                 190


Pro Phe His Gly Tyr Glu Ser Ala Cys Ser Gly Arg His Tyr Cys Leu 
        195                 200                 205


Arg Gly Met Asp Tyr Tyr Ala Ser Gly Ala Pro Cys Thr Asp Arg Arg 
    210                 215                 220


Leu Arg Pro Trp Cys Arg Glu Gln Pro Thr Met Cys Thr Ser Leu Arg 
225                 230                 235                 240


Ala Pro Ala Arg Asn Ala Val Cys Cys Tyr Asn Ser Pro Ala Val Ile 
                245                 250                 255


Leu Pro Ile Ser Glu Pro 
            260


<210>  6066
<211>  290
<212>  DNA
<213>  Homo sapiens

<400>  6066
aaaggcccaa cccctccatg ctcgcggctt cctccttctc cagatgtgta cctccctacg     60

agcaccggcc cggaatgcag tgtgctgtta caactccccc gccgtcatac tacccatatc    120

cgaaccttag atgggacaca agtcacttca agaagtctgg tggtccccag agaaacaact    180

atgttatcca tcctgagttt gtgtctgaga cctatcccga ctatcgttgc tggtagagcc    240

tgggcttgct gtgccaaggg ggcagagcaa taaataaact cttcaacccc               290


<210>  6067
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  6067

Met Leu Ala Ala Ser Ser Phe Ser Arg Cys Val Pro Pro Tyr Glu His 
1               5                   10                  15


Arg Pro Gly Met Gln Cys Ala Val Thr Thr Pro Pro Pro Ser Tyr Tyr 
            20                  25                  30


Pro Tyr Pro Asn Leu Arg Trp Asp Thr Ser His Phe Lys Lys Ser Gly 
        35                  40                  45


Gly Pro Gln Arg Asn Asn Tyr Val Ile His Pro Glu Phe Val Ser Glu 
    50                  55                  60


Thr Tyr Pro Asp Tyr Arg Cys Trp 
65                  70


<210>  6068
<211>  2342
<212>  DNA
<213>  Homo sapiens

<400>  6068
tgacagccgc caacacagag ccctggagag gtggggagct gctgaagggc gggagaagtt     60

gcggcgtggc gataggtctg ggtgttctgg gaggacccct aaaagggagc agctctgcca    120

ggtcagagct tgaggtagca tgtgtgccgc ttccaggagg ccaggatgga gacagcagtt    180

cgaggaatgc ccttggaatg ccctcctagg ccggagcggc tcaatgccta cgagcgcgaa    240

gtgatggtga acatgctgaa ctcactgtcg cggaaccagc agctgccgcg gatcacgccc    300

cgatgcgggt gcgtggaccc gctgcccggc cgcctgccct tccatggtta cgaaagtgct    360

tgctcgggcc gccactactg tctgcgcggg atggactact acgccagcgg ggcgccctgc    420

accgaccgcc gcctgcggcc ttggtgccgg gagcaaccga ctgtaaggtt cgcagggctc    480

cgcccgcctc agccgggctc caccccacac aagccccgcc ccagaacccc gcccccttcc    540

agcccggcca gcttccgtgc aggcccccag cctgctctag ccccgcgctg cacgctctcg    600

aggccctgcc gtgtcccgcc ctcgggctcc aaggcctgaa ctaacaactg aggcgggaga    660

accagcacga aggttactcc aagtccccga cccctgtccc tctcaaactg ggctcaaggt    720

caacctggcc tctctatatg ctctggaggt cccgtcagag ggtttttgag gaagaaaccc    780

cgcacatcag tcgcatcctc ttcccccatc tccttggccc tgcccccttt cctggactcc    840

tggccctaga gacgcaggtt ctagcctgtg gagtgccctg cgttctcaga aaaatgtcct    900

ctcttgctgg tcccccgtca ccgtcggtag tgggtgcggt cattcctggg ggctacgtga    960

gccgggaaat ggtgaccact ttaccagaat ggctctggcc tcctcggatc ccgcaccacc   1020

tgcggaggta ggcaccctcg cgtgttactg ctaagaaaac tgaggcccga gcgcacagct   1080

ggagcccaga ctgcagctcg gcattcgtcc tgcacgcggc ggcagccaag cctgggagaa   1140

ctttgtccgc ggtagcccag agagctgtgc agtgggggtc catagtgatc ccccgcccct   1200

ctccaggccg agagagcctg attcattgtg caagactgag tcttatccct ctcaagggca   1260

taggggagtg ggaaagtgtc tgagcctcta ggaagctcag aaatgatgcc tcgtcctact   1320

gctggagaaa ttgctgtcca gtggcgggga tccggtggtt ccaggtcctc aacgcccgga   1380

gcccgacctt ccccagggtc cagcgctctt tcctcaacgg cagaaatgag gccttgccgg   1440

gagggagtct tccaaggggg gttcccgaat cggtgctgca gtgggggttt tgaagggtga   1500

ggaagaagga gaggaggatt tccgagcctt gggacggaca cctgaagcgc cgcccagggg   1560

cttggtctaa atcgggggat gagagtcaaa aggcccaacc cctccatgct cgcggcttcc   1620

tccttctcca gatgtgtacc tccctacgag caccggcccg gaatgcagtg tgctgttaca   1680

actcccccgc cgtcatacta cccatatccg aaccttaggt aagtctaacg cgcacacact   1740

catttgcaca cgcaccctga aggcttggtg aggcggggct gggggaggat gtctggtaga   1800

cgggatgaga acgctccgcg gtgcactgac aggcacatac cacgaggggg agctagtggc   1860

atggagcagt caaaggtggt aaggacagag gaccttaaga gagggctagg aggccggtat   1920

tgaagggtta caggttggca gtgggcttac agccaaaggc gttggttcag agcttgaagt   1980

aatgagtaag aagtcgatgt taaggaggaa atattgggta tcagcaactt aacagtagaa   2040

cctaaggtca ggaggtcagt attggaaccc aaggtcagtg ctatagacaa agtgtaggga   2100

taaggttagc attgcaaact ggagtcagat attcactttg acatatgagg atccaaaacg   2160

gctgacccat ctcttcctgt agatgggaca caagtcactt caagaagtct ggtggtcccc   2220

agagaaacaa ctatgttatc catcctgagt ttgtgtctga gacctatccc gactatcgtt   2280

gctggtagag cctgggcttg ctgtgccaag ggggcagagc aataaataaa ctcttcaacc   2340

cc                                                                  2342


<210>  6069
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  6069

Met Glu Thr Ala Val Arg Gly Met Pro Leu Glu Cys Pro Pro Arg Pro 
1               5                   10                  15


Glu Arg Leu Asn Ala Tyr Glu Arg Glu Val Met Val Asn Met Leu Asn 
            20                  25                  30


Ser Leu Ser Arg Asn Gln Gln Leu Pro Arg Ile Thr Pro Arg Cys Gly 
        35                  40                  45


Cys Val Asp Pro Leu Pro Gly Arg Leu Pro Phe His Gly Tyr Glu Ser 
    50                  55                  60


Ala Cys Ser Gly Arg His Tyr Cys Leu Arg Gly Met Asp Tyr Tyr Ala 
65                  70                  75                  80


Ser Gly Ala Pro Cys Thr Asp Arg Arg Leu Arg Pro Trp Cys Arg Glu 
                85                  90                  95


Gln Pro Thr Val Arg Phe Ala Gly Leu Arg Pro Pro Gln Pro Gly Ser 
            100                 105                 110


Thr Pro His Lys Pro Arg Pro Arg Thr Pro Pro Pro Ser Ser Pro Ala 
        115                 120                 125


Ser Phe Arg Ala Gly Pro Gln Pro Ala Leu Ala Pro Arg Cys Thr Leu 
    130                 135                 140


Ser Arg Pro Cys Arg Val Pro Pro Ser Gly Ser Lys Ala 
145                 150                 155


<210>  6070
<211>  555
<212>  DNA
<213>  Homo sapiens

<400>  6070
tgacagccgc caacacagag ccctggagag gtggggagct gctgaagggc gggagaagtt     60

gcggcgtggc gataggtctg ggtgttctgg gaggacccct aaaagggagc agctctgcca    120

ggtcagagct tgaggtagca tgtgtgccgc ttccaggagg ccaggatgga gacagcagtt    180

cgaggaatgc ccttggaatg ccctcctagg ccggagcggc tcaatgccta cgagcgcgaa    240

gtgatggtga acatgctgaa ctcactgtcg cggaaccagc agctgccgcg gatcacgccc    300

cgatgcggat gtgtacctcc ctacgagcac cggcccggaa tgcagtgtgc tgttacaact    360

cccccgccgt catactaccc atatccgaac cttagatggg acacaagtca cttcaagaag    420

tctggtggtc cccagagaaa caactatgtt atccatcctg agtttgtgtc tgagacctat    480

cccgactatc gttgctggta gagcctgggc ttgctgtgcc aagggggcag agcaataaat    540

aaactcttca acccc                                                     555


<210>  6071
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  6071

Met Glu Thr Ala Val Arg Gly Met Pro Leu Glu Cys Pro Pro Arg Pro 
1               5                   10                  15


Glu Arg Leu Asn Ala Tyr Glu Arg Glu Val Met Val Asn Met Leu Asn 
            20                  25                  30


Ser Leu Ser Arg Asn Gln Gln Leu Pro Arg Ile Thr Pro Arg Cys Gly 
        35                  40                  45


Cys Val Pro Pro Tyr Glu His Arg Pro Gly Met Gln Cys Ala Val Thr 
    50                  55                  60


Thr Pro Pro Pro Ser Tyr Tyr Pro Tyr Pro Asn Leu Arg Trp Asp Thr 
65                  70                  75                  80


Ser His Phe Lys Lys Ser Gly Gly Pro Gln Arg Asn Asn Tyr Val Ile 
                85                  90                  95


His Pro Glu Phe Val Ser Glu Thr Tyr Pro Asp Tyr Arg Cys Trp 
            100                 105                 110


<210>  6072
<211>  716
<212>  DNA
<213>  Homo sapiens

<400>  6072
tggagggggc atcagtgtgg ggtgggagca ggaaggctgt tggggaagga agctgagaga     60

tcctctgcag gaggggatta tagcagctaa gggcacctgc caggctggag gtgtggcctg    120

tctaggggaa gggtggtcac tgatgtccag caggagccct tgacaggtag agcccaccac    180

ggcatctcca agaccacacc atgttcctgt tctcccgtaa gaccaggacc cctatcagta    240

cctacagtga ctcctacagg gctcccacct ccatcaagga ggtctataag gacccacccc    300

tgtgtgcctg ggaagccaac aagtttctga ctccgggtct gactcatacc atggagcgac    360

atgtggatcc cgaagccctg cagaagatgg ccaaatgtgc tgtacaggac tacacttata    420

gggggtccat atcaggccac ccctacttgc ctgagaagta ctggctttct caagaggaag    480

cagacaaatg cagcccaaac tacctgggca gtgactggta caacacatgg aggatggaac    540

cttacaacag cagctgctgc aacaagtata ccacctacct tcctcggctg cctaaggagg    600

ccaggatgga gacagcagtt cgaggaatgc ccttggaatg ccctcctagg ccggagcggc    660

tcaatgccta cgagcgcgaa gtgatggtga acatgctgaa ctcactgtcg cggaac        716


<210>  6073
<211>  171
<212>  PRT
<213>  Homo sapiens

<400>  6073

Met Phe Leu Phe Ser Arg Lys Thr Arg Thr Pro Ile Ser Thr Tyr Ser 
1               5                   10                  15


Asp Ser Tyr Arg Ala Pro Thr Ser Ile Lys Glu Val Tyr Lys Asp Pro 
            20                  25                  30


Pro Leu Cys Ala Trp Glu Ala Asn Lys Phe Leu Thr Pro Gly Leu Thr 
        35                  40                  45


His Thr Met Glu Arg His Val Asp Pro Glu Ala Leu Gln Lys Met Ala 
    50                  55                  60


Lys Cys Ala Val Gln Asp Tyr Thr Tyr Arg Gly Ser Ile Ser Gly His 
65                  70                  75                  80


Pro Tyr Leu Pro Glu Lys Tyr Trp Leu Ser Gln Glu Glu Ala Asp Lys 
                85                  90                  95


Cys Ser Pro Asn Tyr Leu Gly Ser Asp Trp Tyr Asn Thr Trp Arg Met 
            100                 105                 110


Glu Pro Tyr Asn Ser Ser Cys Cys Asn Lys Tyr Thr Thr Tyr Leu Pro 
        115                 120                 125


Arg Leu Pro Lys Glu Ala Arg Met Glu Thr Ala Val Arg Gly Met Pro 
    130                 135                 140


Leu Glu Cys Pro Pro Arg Pro Glu Arg Leu Asn Ala Tyr Glu Arg Glu 
145                 150                 155                 160


Val Met Val Asn Met Leu Asn Ser Leu Ser Arg 
                165                 170


<210>  6074
<211>  376
<212>  DNA
<213>  Homo sapiens

<400>  6074
tgcctgggaa gccaacaagt ttctgactcc gggtctgact cataccatgg agcgacatgt     60

ggatcccgaa gccctgcaga agatggccaa atgtgctgta caggactaca cttatagggg    120

gtccatatca ggccacccct acttgcctga gaagtactgg ctttctcaag aggaagcaga    180

caaatgcagc ccaaactacc tgggcagtga ctggtacaac acatggagga tggaacctta    240

caacagcagc tgctgcaaca agtataccac ctaccttcct cggctgccta aggtatctgt    300

tgcacccagc acagacgtct ggggactggg acacgcatac cccaccacct cccaaactac    360

agtgactgat atttca                                                    376


<210>  6075
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  6075

Met Glu Arg His Val Asp Pro Glu Ala Leu Gln Lys Met Ala Lys Cys 
1               5                   10                  15


Ala Val Gln Asp Tyr Thr Tyr Arg Gly Ser Ile Ser Gly His Pro Tyr 
            20                  25                  30


Leu Pro Glu Lys Tyr Trp Leu Ser Gln Glu Glu Ala Asp Lys Cys Ser 
        35                  40                  45


Pro Asn Tyr Leu Gly Ser Asp Trp Tyr Asn Thr Trp Arg Met Glu Pro 
    50                  55                  60


Tyr Asn Ser Ser Cys Cys Asn Lys Tyr Thr Thr Tyr Leu Pro Arg Leu 
65                  70                  75                  80


Pro Lys Val Ser Val Ala Pro Ser Thr Asp Val Trp Gly Leu Gly His 
                85                  90                  95


Ala Tyr Pro Thr Thr Ser Gln Thr Thr Val Thr Asp Ile 
            100                 105


<210>  6076
<211>  2478
<212>  DNA
<213>  Homo sapiens

<400>  6076
atctgtgtga ccctgactga attaattaat tttgatgtgt ctcagtttct ccaactttaa     60

aatggggata atagtaccat ttacttcaca gggttgctgt gaggtttaag tgagttagta    120

tatgtaagac atttagaatg atgcttggca cataaaaaac tattatgatt attctactgt    180

tatccttgcc tcacctttga aatcctataa tccagccttg acatagcacc tgtggtactt    240

ttcacaaatg aaaatttgac caagacaccc tcctacttaa aaccctatag ggtttgtctg    300

ccttagcccc cagtcaccta agcctgtcct acaaggccct ccatgatcca acagtctgaa    360

agaatacata tgcgacacgg tgtggaggaa gccctagcga agagcagctg tctgagggga    420

ggggtgcagt gctgggattt ggagttcggg gatggcagtt tgcacatact gaaactgagg    480

tgtttgggga catccagatc aagatgacta taagcatatg aagaagagtg gaattctgat    540

gagaggacaa atctggaaat taggatttga agctgtcagt aattaaaggc ttgtgttaaa    600

tcaaatggcc ttggaggagg agcaagggga gaagagggtg caggataaca ccctgaggaa    660

ccccatgttt ccacagtgga tgcacaggaa agggaggcat cagagaagct gaggaggaag    720

ttgtttcaag aagtagagtg tggtcatagc ctgtgtgctg gaggattaac atacaaaaca    780

acatcaacaa caaaacgagt agagagtggt cagaagagtg caattcattg gtctaggagg    840

gtaaaggtct cagagggtaa agactgcaga gtcctgtgga tttggtaatc agagccatgc    900

aagagcaatt tattgtttca tcataggaga tgcacattcc caacttccat tgggaattct    960

cagtccattc aactcccaaa gtgcttggat tactggcctg agacaccatg cctggctttt   1020

ccttcattct taataccact gctatctgac tttcactcct cgccattcat tgaagctgtc   1080

tggctaagtt accaagagtt actacatccg agagatttct ctgtcactaa cacttgacac   1140

tgatctttgt ctaataatgc tgtctttatt ggtttatctt tgattttcct cctagttctc   1200

tggcaataat tctctgtctt cttttatggc tttttttcct ttacctaccc ttaaatattt   1260

atattctcca aagttatgtc cttggccatt ttctctctct tctttggcaa tttcatctct   1320

tcctatgact tcacccacca tttatatgat gatgacttca agatctctat ctataaccca   1380

gacctctttc ctttgcttca gataagtata tctaactact tgccaaacat cttttcctgg   1440

atatcctcaa atatttttgt tctcaaatga actccaaatc tctaatctgt tattccaaac   1500

ctcagttgat agcattagca ttcctccagc tgccacagcc aaaaactcaa gggtcaccct   1560

aatctctcac cttaccatcc atatggtgac caaaatctgt tcatctactt tttaaaattc   1620

ccttctattg agtatggagt caggcactct catattttgc ttgtggaaat gtaaattgtt   1680

acaaccctta cttattatgg caatttgagg tatatagcaa aagttttaaa aatgtgtata   1740

tcttttctcc taacaatttc atgtctagta atttatccta agggaataat tggaaatgtg   1800

tacaaagata catgtataag aatgattata ctagcaaaat tttataaagt acctaaattt   1860

tcaataagat tccttaaata caccattttg taataaattt tatttatttt tataataaac   1920

aatatttgct tcctgaaagg gcatacgata atatattaac aatggtaatt ttaggtagta   1980

ggattttaga ccttttttct ttgtgcttct ctgagttatc tgcattttct acattcagcg   2040

tatatttatt ttggagttag acaaaataaa ttattttaaa aattctctcc tattcaacga   2100

attccttttt tcattgtgac aatctcctta tctcccacct acatcctcct tcctcatctg   2160

ttcacccctc gctggccttc ctgccctcaa ccccagcccc tgcaattccc tgacactgtg   2220

gccagagtgg cctaactcac aattgaacca tgactctccc tcccaggttc aaaaacctgg   2280

agccttatgt ccacgctcca caacatagcc agagaggccc ttcttggtct gcagactcct   2340

ctctcaccca aggactaaac tctcctgctc taacagtttc agtttctggt aggtccctgc   2400

ccacaggctg ccttttctcc tgactgtctt ctgctggaag cctcctcctc ctggatccct   2460

cagtaggtct gcccttca                                                 2478


<210>  6077
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  6077

Met Ser Leu Ala Ile Phe Ser Leu Phe Phe Gly Asn Phe Ile Ser Ser 
1               5                   10                  15


Tyr Asp Phe Thr His His Leu Tyr Asp Asp Asp Phe Lys Ile Ser Ile 
            20                  25                  30


Tyr Asn Pro Asp Leu Phe Pro Leu Leu Gln Ile Ser Ile Ser Asn Tyr 
        35                  40                  45


Leu Pro Asn Ile Phe Ser Trp Ile Ser Ser Asn Ile Phe Val Leu Lys 
    50                  55                  60


<210>  6078
<211>  2038
<212>  DNA
<213>  Homo sapiens

<400>  6078
gggtaaggtg ggccttacag acaggctgag gtttgggtgg tgtgatctgt cctaattggc     60

ccctcaccaa tgcatctatc tgtctgccac cagcccaccc caccctgccc ccaccctcac    120

ccacgcttct gctcattggt ctcaatccca gcctggaagc agggagtaag gctggactcc    180

aatggcccat tcccctcacc ccagcccaag acgtgggagg ctgcttccca gtaagaatcc    240

aggagcaagc tttggtgaat ccagtgggct gagtggctct atggatgtgg ttgtttggat    300

gtggtaggga gtgcttagca gaatgtgtgt gtatctctga ggctgtcagg gggtgggtgg    360

gtgtgtgtct ctgttggacc tgtctctcct cagtctattc ctgtcataga tgtgggtgtc    420

cctggtaggg aagtgcctgt gtggtctgtt tacagtgcag aaggcggctc agcagtgcaa    480

tgggctgaca gccttggacc gggagtcaga agcctgggtt ctggttgtag ctctggcccc    540

tccctgtgat cttcaacaag ccacttgctt tctctcgtct tcagtttcct caactagaaa    600

atgaacagca gctgaaatta tgttgaagat ccttttatac ctgaaagagt ttcttcatag    660

aaatttctgt ggtggggagg gggcaatctc tgtgtgtctc agtataccta aaggttgggg    720

tggggcggag ttgtgtgtct ctgtagaaag gcgaaggggc agttcctatc aggactgtgt    780

atgtctgagc acatgtggct ctgtttggga ttacgtgttt gtctgtgaat gtgtgtgtgt    840

gttggagggt tgtctattgt gtgtggctgt atagggtgtc tgtagatcaa gatgtgtata    900

cagctgcttc tgctattgct ggtttggggg aggggactgg aaagctgaga ctgaaaatca    960

agagggaaga ggtgggagct ggaatgggga gcaatgagag gagggagtga gactgttggc   1020

ttaggaaggg tggtacctct ccctgcatca tacccaggaa ctgccagctc caaaatattg   1080

gggtacagct caccaccccc cactccgcca acccattcct acctcctcta gtgcagggac   1140

ccaagttaga tgatgagaaa atgccaaaca aagggaggca aggacagaga aggtacctgc   1200

aggacccaca aggcccatac tggcccccat ctgaacccac ctctcccacc cagatcaaca   1260

tccccccaac ccctgtgccc ccatcatctg gaccccagag ccagccctcc cactaccacc   1320

accaccaccc cggggctcct tggctcacct ttctagaaca tgggtacctc ctctttttgg   1380

gggctcattt agactgctgc ctttgctgct gacttgcagt gtgactcggg cccattgttc   1440

aatctctgtg gccctgagac accagggaaa atctcccccc ccacaggaca tactagttcc   1500

ctggcaggca agggcttcca actgaggcag tgcatgtgtg gcagagagag gcaggaagct   1560

ggcagtggca gcttctgtgt ctagggaggg gtgtggctcc ctccttccct gtctgggagg   1620

ttggagggaa gaatctaggc cttagcttgc cctcctgcca cccttcccct tgtagatact   1680

gccttaacac tccctcctct ctcagctgtg gctgccaccc agccaggttt ctccgtgctc   1740

actaatttat ttccaggaag gtgtgtggaa gacatgagcc gtgtataata ttttttttaa   1800

cattttcatt gcagtattga ccatcatcct tggttgtgta tcgtgtaaca caaataatga   1860

tattaaaagc atcaaacaag ccagcctcag ctccctccct ggggtgtggg caaggggcag   1920

atgggctggg aagcagacag aactggtcct ctgggcacac atgttactcc acctccacct   1980

gtgggttccc aggcatgcca ctgacctgct gcatgaccct gggtgagtca caacccct     2038


<210>  6079
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  6079

Met Leu Lys Ile Leu Leu Tyr Leu Lys Glu Phe Leu His Arg Asn Phe 
1               5                   10                  15


Cys Gly Gly Glu Gly Ala Ile Ser Val Cys Leu Ser Ile Pro Lys Gly 
            20                  25                  30


Trp Gly Gly Ala Glu Leu Cys Val Ser Val Glu Arg Arg Arg Gly Ser 
        35                  40                  45


Ser Tyr Gln Asp Cys Val Cys Leu Ser Thr Cys Gly Ser Val Trp Asp 
    50                  55                  60


Tyr Val Phe Val Cys Glu Cys Val Cys Val Leu Glu Gly Cys Leu Leu 
65                  70                  75                  80


Cys Val Ala Val 



<210>  6080
<211>  3765
<212>  DNA
<213>  Homo sapiens

<400>  6080
gtcaccgcag tggctgagct gctgacagga ggcggcagcg gagtaggagg cgaggcaaga     60

cctgcggctc ggcccggcca cagccgcggt agtgctaggc aagcccacgg agtcacgccg    120

gcctcagcca gtctgcgaac ctctcgcccc cgcccacccc tgcatccgcc cggcccctgc    180

ccgcccgagt ggtccgggga ggcctagtct gcaccacccg ccgggctcct ggggccgccg    240

ccccgcgcgg tcctgtcggc gtccgcggcc gcgcccggcc cctggcccgc tcgcccgccg    300

gcaccatgat ggaggagatc gaccggttcc aggacccagc cgccgcctcc atctctgacg    360

gagactgtga cgcccgggag ggtgagtcag tagccatgaa ttacaaacca tccccgctcc    420

aagtgaagct ggagaagcag cgggagctgg cccggaaggg ctccctgaag aatggcagca    480

tgggtagccc tgtcaaccag caacccaaga agaacaatgt catggcccga acaaggctgg    540

tcgtccccaa taaaggctac tcctcacttg accagagccc tgatgagaag ccactggtag    600

cccttgacac ggacagcgat gatgactttg acatgtctag atactcctcc tccggctact    660

cctctgctga gcagatcaac caagatttga acatccagct gctgaaggac ggctaccggt    720

tagatgagat ccccgacgac gaggacctag acctcatccc ccccaagtcc gtgaacccca    780

cgtgcatgtg ctgccaggcc acgtcctcca ccgcctgcca cattcagtag cgggcggggc    840

cactgcggtc gccggggcgg ggccgccaag ggccgggtag gacgggcaga ggccgacccc    900

ttcccagctc gtctgcctgc ccccggcccc gcgcccctac agccgccaac ctcgtataac    960

agtcattgct tcctcctatg gtaggacgtg tacctctgtg tgttcatgga gctggagaaa   1020

ccaaaactgg gtctctctcc acccgggagc tgaggagggg tgggggccgt ttgttcagtt   1080

acctggggga acctcaccca gcaccctgcc ccgcttccca gggctggcca agagagaaga   1140

ctggacggca gggaggtcaa cattaacgag tggggggatc acaaagccag gggcttggcc   1200

ccaccccagc gaagccatga actcccaagc cccggcctca gcctaaccag gaaaggggct   1260

cggagggaga aaggcccagg gcagtgggga cgggtcccag cacctcggag cccccttcac   1320

acgcccccta ccggcccatg tttctatttg catttccccc tcctcagatg ggaagcctgg   1380

caaagctgcc caaccgggta gtgcccctca cccatcggat cactgccttc ttcctcctct   1440

tgccccattc acccgcttcc ttgcactctg ggagtggggc agggtaaggt gggccttaca   1500

gacaggctga ggtttgggtg gtgtgatctg tcctaattgg cccctcacca atgcatctat   1560

ctgtctgcca ccagcccacc ccaccctgcc cccaccctca cccacgcttc tgctcattgg   1620

tctcaatccc agcctggaag cagggagtaa ggctggactc caatggccca ttcccctcac   1680

cccagcccaa gacgtgggag gctgcttccc agtaagaatc caggagcaag ctttggtgaa   1740

tccagtgggc tgagtggctc tatggatgtg gttgtttgga tgtggtaggg agtgcttagc   1800

agaatgtgtg tgtatctctg aggctgtcag ggggtgggtg ggtgtgtgtc tctgttggac   1860

ctgtctctcc tcagtctatt cctgtcatag atgtgggtgt ccctggtagg gaagtgcctg   1920

tgtggtctgt ttacagtgca gaaggcggct cagcagtgca atgggctgac agccttggac   1980

cgggagtcag aagcctgggt tctggttgta gctctggccc ctccctgtga tcttcaacaa   2040

gccacttgct ttctctcgtc ttcagtttcc tcaactagaa aatgaacagc agctgaaatt   2100

atgttgaaga tccttttata cctgaaagag tttcttcata gaaatttctg tggtggggag   2160

ggggcaatct ctgtgtgtct cagtatacct aaaggttggg gtggggcgga gttgtgtgtc   2220

tctgtagaaa ggcgaagggg cagttcctat caggactgtg tatgtctgag cacatgtggc   2280

tctgtttggg attacgtgtt tgtctgtgaa tgtgtgtgtg tgttggaggg ttgtctattg   2340

tgtgtggctg tatagggtgt ctgtagatca agatgtgtat acagctgctt ctgctattgc   2400

tggtttgggg gaggggactg gaaagctgag actgaaaatc aagagggaag aggtgaggaa   2460

ggcccacccc tggggctggg cagtgtagac ctgccaccgt gtgaagaaaa atgaaagcac   2520

agatagccta agactgcaca ggcctgtgcc cacatacctt atagcacagg cccaggtgga   2580

tcatctcatg ctaacacccc acatgtgctg gtggatccac tcccatggat ccactcacat   2640

gctgcaggca tgcagtagac tcacccacag cccactctct ggacaccaat cctgggaggt   2700

gggagctgga atggggagca atgagaggag ggagtgagac tgttggctta ggaagggtgg   2760

tacctctccc tgcatcatac ccaggaactg ccagctccaa aatattgggg tacagctcac   2820

caccccccac tccgccaacc cattcctacc tcctctagtg cagggaccca agttagatga   2880

tgagaaaatg ccaaacaaag ggaggcaagg acagagaagg tacctgcagg acccacaagg   2940

cccatactgg cccccatctg aacccacctc tcccacccag atcaacatcc ccccaacccc   3000

tgtgccccca tcatctggac cccagagcca gccctcccac taccaccacc accaccccgg   3060

ggctccttgg ctcacctttc tagaacatgg gtacctcctc tttttggggg ctcatttaga   3120

ctgctgcctt tgctgctgac ttgcagtgtg actcgggccc attgttcaat ctctgtggcc   3180

ctgagacacc agggaaaatc tcccccccca caggacatac tagttccctg gcaggcaagg   3240

gcttccaact gaggcagtgc atgtgtggca gagagaggca ggaagctggc agtggcagct   3300

tctgtgtcta gggaggggtg tggctccctc cttccctgtc tgggaggttg gagggaagaa   3360

tctaggcctt agcttgccct cctgccaccc ttccccttgt agatactgcc ttaacactcc   3420

ctcctctctc agctgtggct gccacccagc caggtttctc cgtgctcact aatttatttc   3480

caggaaggtg tgtggaagac atgagccgtg tataatattt tttttaacat tttcattgca   3540

gtattgacca tcatccttgg ttgtgtatcg tgtaacacaa ataatgatat taaaagcatc   3600

aaacaagcca gcctcagctc cctccctggg gtgtgggcaa ggggcagatg ggctgggaag   3660

cagacagaac tggtcctctg ggcacacatg ttactccacc tccacctgtg ggttcccagg   3720

catgccactg acctgctgca tgaccctggg tgagtcacaa cccct                   3765


<210>  6081
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  6081

Met Met Glu Glu Ile Asp Arg Phe Gln Asp Pro Ala Ala Ala Ser Ile 
1               5                   10                  15


Ser Asp Gly Asp Cys Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn 
            20                  25                  30


Tyr Lys Pro Ser Pro Leu Gln Val Lys Leu Glu Lys Gln Arg Glu Leu 
        35                  40                  45


Ala Arg Lys Gly Ser Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn 
    50                  55                  60


Gln Gln Pro Lys Lys Asn Asn Val Met Ala Arg Thr Arg Leu Val Val 
65                  70                  75                  80


Pro Asn Lys Gly Tyr Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro 
                85                  90                  95


Leu Val Ala Leu Asp Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg 
            100                 105                 110


Tyr Ser Ser Ser Gly Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu 
        115                 120                 125


Asn Ile Gln Leu Leu Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp 
    130                 135                 140


Asp Glu Asp Leu Asp Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys 
145                 150                 155                 160


Met Cys Cys Gln Ala Thr Ser Ser Thr Ala Cys His Ile Gln 
                165                 170


<210>  6082
<211>  3435
<212>  DNA
<213>  Homo sapiens

<400>  6082
gagtcaccgc agtggctgag ctgctgacag gaggcggcag cggagtagga ggcgaggcaa     60

gacctgcggc tcggcccggc cacagccgcg gtagtgctag gcaagcccac ggagtcacgc    120

cggcctcagc cagtctgcga acctctcgcc cccgcccacc cctgcatccg cccggcccct    180

gcccgcccga gtggtccggg gagcatgatg gaggagatcg accggttcca ggacccagcc    240

gccgcctcca tctctgacgg agactgtgac gcccgggagg agaagcagcg ggagctggcc    300

cggaagggct ccctgaagaa tggcagcatg ggtagccctg tcaaccagca acccaagaag    360

aacaatgtca tggcccgaac aaggctggtc gtccccaata aaggctactc ctcacttgac    420

cagagccctg atgagaagcc actggtagcc cttgacacgg acagcgatga tgactttgac    480

atgtctagat actcctcctc cggctactcc tctgctgagc agatcaacca agatttgaac    540

atccagctgc tgaaggacgg ctaccggtta gatgagatcc ccgacgacga ggacctagac    600

ctcatccccc ccaagtccgt gaaccccacg tgcatgtgct gccaggccac gtcctccacc    660

gcctgccaca ttcagtagcg ggcggggcca ctgcggtcgc cggggcgggg ccgccaaggg    720

ccgggtagga cgggcagagg ccgacccctt cccagctcgt ctgcctgccc ccggccccgc    780

gcccctacag ccgccaacct cgtataacag tcattgcttc ctcctatggt aggacgtgta    840

cctctgtgtg ttcatggagc tggagaaacc aaaactgggt ctctctccac ccgggagctg    900

aggaggggtg ggggccgttt gttcagttac ctgggggaac ctcacccagc accctgcccc    960

gcttcccagg gctggccaag agagaagact ggacggcagg gaggtcaaca ttaacgagtg   1020

gggggatcac aaagccaggg gcttggcccc accccagcga agccatgaac tcccaagccc   1080

cggcctcagc ctaaccagga aaggggctcg gagggagaaa ggcccagggc agtggggacg   1140

ggtcccagca cctcggagcc cccttcacac gccccctacc ggcccatgtt tctatttgca   1200

tttccccctc ctcagatggg aagcctggca aagctgccca accgggtagt gcccctcacc   1260

catcggatca ctgccttctt cctcctcttg ccccattcac ccgcttcctt gcactctggg   1320

agtggggcag ggtaaggtgg gccttacaga caggctgagg tttgggtggt gtgatctgtc   1380

ctaattggcc cctcaccaat gcatctatct gtctgccacc agcccacccc accctgcccc   1440

caccctcacc cacgcttctg ctcattggtc tcaatcccag cctggaagca gggagtaagg   1500

ctggactcca atggcccatt cccctcaccc cagcccaaga cgtgggaggc tgcttcccag   1560

taagaatcca ggagcaagct ttggtgaatc cagtgggctg agtggctcta tggatgtggt   1620

tgtttggatg tggtagggag tgcttagcag aatgtgtgtg tatctctgag gctgtcaggg   1680

ggtgggtggg tgtgtgtctc tgttggacct gtctctcctc agtctattcc tgtcatagat   1740

gtgggtgtcc ctggtaggga agtgcctgtg tggtctgttt acagtgtata cctgaaagag   1800

tttcttcata gaaatttctg tggtggggag ggggcaatct ctgtgtgtct cagtatacct   1860

aaaggttggg gtggggcgga gttgtgtgtc tctgtagaaa ggcgaagggg cagttcctat   1920

caggactgtg tatgtctgag cacatgtggc tctgtttggg attacgtgtt tgtctgtgaa   1980

tgtgtgtgtg tgttggaggg ttgtctattg tgtgtggctg tatagggtgt ctgtagatca   2040

agatgtgtat acagctgctt ctgctattgc tggtttgggg gaggggactg gaaagctgag   2100

actgaaaatc aagagggaag aggtgaggaa ggcccacccc tggggctggg cagtgtagac   2160

ctgccaccgt gtgaagaaaa atgaaagcac agatagccta agactgcaca ggcctgtgcc   2220

cacatacctt atagcacagg cccaggtgga tcatctcatg ctaacacccc acatgtgctg   2280

gtggatccac tcccatggat ccactcacat gctgcaggca tgcagtagac tcacccacag   2340

cccactctct ggacaccaat cctgggaggt gggagctgga atggggagca atgagaggag   2400

ggagtgagac tgttggctta ggaagggtgg tacctctccc tgcatcatac ccaggaactg   2460

ccagctccaa aatattgggg tacagctcac caccccccac tccgccaacc cattcctacc   2520

tcctctagtg cagggaccca agttagatga tgagaaaatg ccaaacaaag ggaggcaagg   2580

acagagaagg tacctgcagg acccacaagg cccatactgg cccccatctg aacccacctc   2640

tcccacccag atcaacatcc ccccaacccc tgtgccccca tcatctggac cccagagcca   2700

gccctcccac taccaccacc accaccccgg ggctccttgg ctcacctttc tagaacatgg   2760

gtacctcctc tttttggggg ctcatttaga ctgctgcctt tgctgctgac ttgcagtgtg   2820

actcgggccc attgttcaat ctctgtggcc ctgagacacc agggaaaatc tcccccccca   2880

caggacatac tagttccctg gcaggcaagg gcttccaact gaggcagtgc atgtgtggca   2940

gagagaggca ggaagctggc agtggcagct tctgtgtcta gggaggggtg tggctccctc   3000

cttccctgtc tgggaggttg gagggaagaa tctaggcctt agcttgccct cctgccaccc   3060

ttccccttgt agatactgcc ttaacactcc ctcctctctc agctgtggct gccacccagc   3120

caggtttctc cgtgctcact aatttatttc caggaaggtg tgtggaagac atgagccgtg   3180

tataatattt tttttaacat tttcattgca gtattgacca tcatccttgg ttgtgtatcg   3240

tgtaacacaa ataatgatat taaaagcatc aaacaagcca gcctcagctc cctccctggg   3300

gtgtgggcaa ggggcagatg ggctgggaag cagacagaac tggtcctctg ggcacacatg   3360

ttactccacc tccacctgtg ggttcccagg catgccactg acctgctgca tgaccctggg   3420

tgagtcacaa cccct                                                    3435


<210>  6083
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  6083

Met Met Glu Glu Ile Asp Arg Phe Gln Asp Pro Ala Ala Ala Ser Ile 
1               5                   10                  15


Ser Asp Gly Asp Cys Asp Ala Arg Glu Glu Lys Gln Arg Glu Leu Ala 
            20                  25                  30


Arg Lys Gly Ser Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln 
        35                  40                  45


Gln Pro Lys Lys Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro 
    50                  55                  60


Asn Lys Gly Tyr Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu 
65                  70                  75                  80


Val Ala Leu Asp Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr 
                85                  90                  95


Ser Ser Ser Gly Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn 
            100                 105                 110


Ile Gln Leu Leu Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp 
        115                 120                 125


Glu Asp Leu Asp Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met 
    130                 135                 140


Cys Cys Gln Ala Thr Ser Ser Thr Ala Cys His Ile Gln 
145                 150                 155


<210>  6084
<211>  1894
<212>  DNA
<213>  Homo sapiens

<400>  6084
gagtcaccgc agtggctgag ctgctgacag gaggcggcag cggagtagga ggcgaggcaa     60

gacctgcggc tcggcccggc cacagccgcg gtagtgctag gcaagcccac ggagtcacgc    120

cggcctcagc cagtctgcga acctctcgcc cccgcccacc cctgcatccg cccggcccct    180

gcccgcccga gtggtccggg gaggcctagt ctgcaccacc cgccgggctc ctggggccgc    240

cgccccgcgc ggtcctgtcg gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc    300

cggcaccatg atggaggaga tcgaccggtt ccaggtgccc accgcgcact cggagatgca    360

gccgctggac ccagccgccg cctccatctc tgacggagac tgtgacgccc gggagggtga    420

gtcagtagcc atgaattaca aaccatcccc gctccaagtg aagctgggtg agtgtgttgt    480

atagggtgtc tgtagatcaa gatgtgtata cagctgcttc tgctattgct ggtttggggg    540

aggggactgg aaagctgaga ctgaaaatca agagggaaga ggtgaggaag gcccacccct    600

ggggctgggc agtgtagacc tgccaccgtg tgaagaaaaa tgaaagcaca gatagcctaa    660

gactgcacag gcctgtgccc acatacctta tagcacaggc ccaggtggat catctcatgc    720

taacacccca catgtgctgg tggatccact cccatggatc cactcacatg ctgcaggcat    780

gcagtagact cacccacagc ccactctctg gacaccaatc ctgggaggtg ggagctggaa    840

tggggagcaa tgagaggagg gagtgagact gttggcttag gaagggtggt acctctccct    900

gcatcatacc caggaactgc cagctccaaa atattggggt acagctcacc accccccact    960

ccgccaaccc attcctacct cctctagtgc agggacccaa gttagatgat gagaaaatgc   1020

caaacaaagg gaggcaagga cagagaaggt acctgcagga cccacaaggc ccatactggc   1080

ccccatctga acccacctct cccacccaga tcaacatccc cccaacccct gtgcccccat   1140

catctggacc ccagagccag ccctcccact accaccacca ccaccccggg gctccttggc   1200

tcacctttct agaacatggg tacctcctct ttttgggggc tcatttagac tgctgccttt   1260

gctgctgact tgcagtgtga ctcgggccca ttgttcaatc tctgtggccc tgagacacca   1320

gggaaaatct ccccccccac aggacatact agttccctgg caggcaaggg cttccaactg   1380

aggcagtgca tgtgtggcag agagaggcag gaagctggca gtggcagctt ctgtgtctag   1440

ggaggggtgt ggctccctcc ttccctgtct gggaggttgg agggaagaat ctaggcctta   1500

gcttgccctc ctgccaccct tccccttgta gatactgcct taacactccc tcctctctca   1560

gctgtggctg ccacccagcc aggtttctcc gtgctcacta atttatttcc aggaaggtgt   1620

gtggaagaca tgagccgtgt ataatatttt ttttaacatt ttcattgcag tattgaccat   1680

catccttggt tgtgtatcgt gtaacacaaa taatgatatt aaaagcatca aacaagccag   1740

cctcagctcc ctccctgggg tgtgggcaag gggcagatgg gctgggaagc agacagaact   1800

ggtcctctgg gcacacatgt tactccacct ccacctgtgg gttcccaggc atgccactga   1860

cctgctgcat gaccctgggt gagtcacaac ccct                               1894


<210>  6085
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  6085

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn Tyr Lys Pro Ser Pro 
        35                  40                  45


Leu Gln Val Lys Leu Gly Glu Cys Val Val 
    50                  55


<210>  6086
<211>  3840
<212>  DNA
<213>  Homo sapiens

<400>  6086
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggtgccc accgcgcact cggagatgca gccgctggac ccagccgccg    420

cctccatctc tgacggagac tgtgacgccc gggagggtga gtcagtagcc atgaattaca    480

aaccatcccc gctccaagtg aagctggaga agcagcggga gctggcccgg aagggctccc    540

tgaagaatgg cagcatgggt agccctgtca accagcaacc caagaagaac aatgtcatgg    600

cccgaacaag gctggtcgtc cccaataaag gctactcctc acttgaccag agccctgatg    660

agaagccact ggtagccctt gacacggaca gcgatgatga ctttgacatg tctagatact    720

cctcctccgg ctactcctct gctgagcaga tcaaccaaga tttgaacatc cagctgctga    780

aggacggcta ccggttagat gagatccccg acgacgagga cctagacctc atccccccca    840

agtccgtgaa ccccacgtgc atgtgctgcc aggccacgtc ctccaccgcc tgccacattc    900

agtagcgggc ggggccactg cggtcgccgg ggcggggccg ccaagggccg ggtaggacgg    960

gcagaggccg accccttccc agctcgtctg cctgcccccg gccccgcgcc cctacagccg   1020

ccaacctcgt ataacagtca ttgcttcctc ctatggtagg acgtgtacct ctgtgtgttc   1080

atggagctgg agaaaccaaa actgggtctc tctccacccg ggagctgagg aggggtgggg   1140

gccgtttgtt cagttacctg ggggaacctc acccagcacc ctgccccgct tcccagggct   1200

ggccaagaga gaagactgga cggcagggag gtcaacatta acgagtgggg ggatcacaaa   1260

gccaggggct tggccccacc ccagcgaagc catgaactcc caagccccgg cctcagccta   1320

accaggaaag gggctcggag ggagaaaggc ccagggcagt ggggacgggt cccagcacct   1380

cggagccccc ttcacacgcc ccctaccggc ccatgtttct atttgcattt ccccctcctc   1440

agatgggaag cctggcaaag ctgcccaacc gggtagtgcc cctcacccat cggatcactg   1500

ccttcttcct cctcttgccc cattcacccg cttccttgca ctctgggagt ggggcagggt   1560

aaggtgggcc ttacagacag gctgaggttt gggtggtgtg atctgtccta attggcccct   1620

caccaatgca tctatctgtc tgccaccagc ccaccccacc ctgcccccac cctcacccac   1680

gcttctgctc attggtctca atcccagcct ggaagcaggg agtaaggctg gactccaatg   1740

gcccattccc ctcaccccag cccaagacgt gggaggctgc ttcccagtaa gaatccagga   1800

gcaagctttg gtgaatccag tgggctgagt ggctctatgg atgtggttgt ttggatgtgg   1860

tagggagtgc ttagcagaat gtgtgtgtat ctctgaggct gtcagggggt gggtgggtgt   1920

gtgtctctgt tggacctgtc tctcctcagt ctattcctgt catagatgtg ggtgtccctg   1980

gtagggaagt gcctgtgtgg tctgtttaca gtgcagaagg cggctcagca gtgcaatggg   2040

ctgacagcct tggaccggga gtcagaagcc tgggttctgg ttgtagctct ggcccctccc   2100

tgtgatcttc aacaagccac ttgctttctc tcgtcttcag tttcctcaac tagaaaatga   2160

acagcagctg aaattatgtt gaagatcctt ttatacctga aagagtttct tcatagaaat   2220

ttctgtggtg gggagggggc aatctctgtg tgtctcagta tacctaaagg ttggggtggg   2280

gcggagttgt gtgtctctgt agaaaggcga aggggcagtt cctatcagga ctgtgtatgt   2340

ctgagcacat gtggctctgt ttgggattac gtgtttgtct gtgaatgtgt gtgtgtgttg   2400

gagggttgtc tattgtgtgt ggctgtatag ggtgtctgta gatcaagatg tgtatacagc   2460

tgcttctgct attgctggtt tgggggaggg gactggaaag ctgagactga aaatcaagag   2520

ggaagaggtg aggaaggccc acccctgggg ctgggcagtg tagacctgcc accgtgtgaa   2580

gaaaaatgaa agcacagata gcctaagact gcacaggcct gtgcccacat accttatagc   2640

acaggcccag gtggatcatc tcatgctaac accccacatg tgctggtgga tccactccca   2700

tggatccact cacatgctgc aggcatgcag tagactcacc cacagcccac tctctggaca   2760

ccaatcctgg gaggtgggag ctggaatggg gagcaatgag aggagggagt gagactgttg   2820

gcttaggaag ggtggtacct ctccctgcat catacccagg aactgccagc tccaaaatat   2880

tggggtacag ctcaccaccc cccactccgc caacccattc ctacctcctc tagtgcaggg   2940

acccaagtta gatgatgaga aaatgccaaa caaagggagg caaggacaga gaaggtacct   3000

gcaggaccca caaggcccat actggccccc atctgaaccc acctctccca cccagatcaa   3060

catcccccca acccctgtgc ccccatcatc tggaccccag agccagccct cccactacca   3120

ccaccaccac cccggggctc cttggctcac ctttctagaa catgggtacc tcctcttttt   3180

gggggctcat ttagactgct gcctttgctg ctgacttgca gtgtgactcg ggcccattgt   3240

tcaatctctg tggccctgag acaccaggga aaatctcccc ccccacagga catactagtt   3300

ccctggcagg caagggcttc caactgaggc agtgcatgtg tggcagagag aggcaggaag   3360

ctggcagtgg cagcttctgt gtctagggag gggtgtggct ccctccttcc ctgtctggga   3420

ggttggaggg aagaatctag gccttagctt gccctcctgc cacccttccc cttgtagata   3480

ctgccttaac actccctcct ctctcagctg tggctgccac ccagccaggt ttctccgtgc   3540

tcactaattt atttccagga aggtgtgtgg aagacatgag ccgtgtataa tatttttttt   3600

aacattttca ttgcagtatt gaccatcatc cttggttgtg tatcgtgtaa cacaaataat   3660

gatattaaaa gcatcaaaca agccagcctc agctccctcc ctggggtgtg ggcaaggggc   3720

agatgggctg ggaagcagac agaactggtc ctctgggcac acatgttact ccacctccac   3780

ctgtgggttc ccaggcatgc cactgacctg ctgcatgacc ctgggtgagt cacaacccct   3840


<210>  6087
<211>  185
<212>  PRT
<213>  Homo sapiens

<400>  6087

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn Tyr Lys Pro Ser Pro 
        35                  40                  45


Leu Gln Val Lys Leu Glu Lys Gln Arg Glu Leu Ala Arg Lys Gly Ser 
    50                  55                  60


Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln Gln Pro Lys Lys 
65                  70                  75                  80


Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro Asn Lys Gly Tyr 
                85                  90                  95


Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu Val Ala Leu Asp 
            100                 105                 110


Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr Ser Ser Ser Gly 
        115                 120                 125


Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn Ile Gln Leu Leu 
    130                 135                 140


Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp Glu Asp Leu Asp 
145                 150                 155                 160


Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met Cys Cys Gln Ala 
                165                 170                 175


Thr Ser Ser Thr Ala Cys His Ile Gln 
            180                 185


<210>  6088
<211>  3789
<212>  DNA
<213>  Homo sapiens

<400>  6088
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggtgccc accgcgcact cggagatgca gccgctggac ccagccgccg    420

cctccatctc tgacggagac tgtgacgccc gggaggagaa gcagcgggag ctggcccgga    480

agggctccct gaagaatggc agcatgggta gccctgtcaa ccagcaaccc aagaagaaca    540

atgtcatggc ccgaacaagg ctggtcgtcc ccaataaagg ctactcctca cttgaccaga    600

gccctgatga gaagccactg gtagcccttg acacggacag cgatgatgac tttgacatgt    660

ctagatactc ctcctccggc tactcctctg ctgagcagat caaccaagat ttgaacatcc    720

agctgctgaa ggacggctac cggttagatg agatccccga cgacgaggac ctagacctca    780

tcccccccaa gtccgtgaac cccacgtgca tgtgctgcca ggccacgtcc tccaccgcct    840

gccacattca gtagcgggcg gggccactgc ggtcgccggg gcggggccgc caagggccgg    900

gtaggacggg cagaggccga ccccttccca gctcgtctgc ctgcccccgg ccccgcgccc    960

ctacagccgc caacctcgta taacagtcat tgcttcctcc tatggtagga cgtgtacctc   1020

tgtgtgttca tggagctgga gaaaccaaaa ctgggtctct ctccacccgg gagctgagga   1080

ggggtggggg ccgtttgttc agttacctgg gggaacctca cccagcaccc tgccccgctt   1140

cccagggctg gccaagagag aagactggac ggcagggagg tcaacattaa cgagtggggg   1200

gatcacaaag ccaggggctt ggccccaccc cagcgaagcc atgaactccc aagccccggc   1260

ctcagcctaa ccaggaaagg ggctcggagg gagaaaggcc cagggcagtg gggacgggtc   1320

ccagcacctc ggagccccct tcacacgccc cctaccggcc catgtttcta tttgcatttc   1380

cccctcctca gatgggaagc ctggcaaagc tgcccaaccg ggtagtgccc ctcacccatc   1440

ggatcactgc cttcttcctc ctcttgcccc attcacccgc ttccttgcac tctgggagtg   1500

gggcagggta aggtgggcct tacagacagg ctgaggtttg ggtggtgtga tctgtcctaa   1560

ttggcccctc accaatgcat ctatctgtct gccaccagcc caccccaccc tgcccccacc   1620

ctcacccacg cttctgctca ttggtctcaa tcccagcctg gaagcaggga gtaaggctgg   1680

actccaatgg cccattcccc tcaccccagc ccaagacgtg ggaggctgct tcccagtaag   1740

aatccaggag caagctttgg tgaatccagt gggctgagtg gctctatgga tgtggttgtt   1800

tggatgtggt agggagtgct tagcagaatg tgtgtgtatc tctgaggctg tcagggggtg   1860

ggtgggtgtg tgtctctgtt ggacctgtct ctcctcagtc tattcctgtc atagatgtgg   1920

gtgtccctgg tagggaagtg cctgtgtggt ctgtttacag tgcagaaggc ggctcagcag   1980

tgcaatgggc tgacagcctt ggaccgggag tcagaagcct gggttctggt tgtagctctg   2040

gcccctccct gtgatcttca acaagccact tgctttctct cgtcttcagt ttcctcaact   2100

agaaaatgaa cagcagctga aattatgttg aagatccttt tatacctgaa agagtttctt   2160

catagaaatt tctgtggtgg ggagggggca atctctgtgt gtctcagtat acctaaaggt   2220

tggggtgggg cggagttgtg tgtctctgta gaaaggcgaa ggggcagttc ctatcaggac   2280

tgtgtatgtc tgagcacatg tggctctgtt tgggattacg tgtttgtctg tgaatgtgtg   2340

tgtgtgttgg agggttgtct attgtgtgtg gctgtatagg gtgtctgtag atcaagatgt   2400

gtatacagct gcttctgcta ttgctggttt gggggagggg actggaaagc tgagactgaa   2460

aatcaagagg gaagaggtga ggaaggccca cccctggggc tgggcagtgt agacctgcca   2520

ccgtgtgaag aaaaatgaaa gcacagatag cctaagactg cacaggcctg tgcccacata   2580

ccttatagca caggcccagg tggatcatct catgctaaca ccccacatgt gctggtggat   2640

ccactcccat ggatccactc acatgctgca ggcatgcagt agactcaccc acagcccact   2700

ctctggacac caatcctggg aggtgggagc tggaatgggg agcaatgaga ggagggagtg   2760

agactgttgg cttaggaagg gtggtacctc tccctgcatc atacccagga actgccagct   2820

ccaaaatatt ggggtacagc tcaccacccc ccactccgcc aacccattcc tacctcctct   2880

agtgcaggga cccaagttag atgatgagaa aatgccaaac aaagggaggc aaggacagag   2940

aaggtacctg caggacccac aaggcccata ctggccccca tctgaaccca cctctcccac   3000

ccagatcaac atccccccaa cccctgtgcc cccatcatct ggaccccaga gccagccctc   3060

ccactaccac caccaccacc ccggggctcc ttggctcacc tttctagaac atgggtacct   3120

cctctttttg ggggctcatt tagactgctg cctttgctgc tgacttgcag tgtgactcgg   3180

gcccattgtt caatctctgt ggccctgaga caccagggaa aatctccccc cccacaggac   3240

atactagttc cctggcaggc aagggcttcc aactgaggca gtgcatgtgt ggcagagaga   3300

ggcaggaagc tggcagtggc agcttctgtg tctagggagg ggtgtggctc cctccttccc   3360

tgtctgggag gttggaggga agaatctagg ccttagcttg ccctcctgcc acccttcccc   3420

ttgtagatac tgccttaaca ctccctcctc tctcagctgt ggctgccacc cagccaggtt   3480

tctccgtgct cactaattta tttccaggaa ggtgtgtgga agacatgagc cgtgtataat   3540

atttttttta acattttcat tgcagtattg accatcatcc ttggttgtgt atcgtgtaac   3600

acaaataatg atattaaaag catcaaacaa gccagcctca gctccctccc tggggtgtgg   3660

gcaaggggca gatgggctgg gaagcagaca gaactggtcc tctgggcaca catgttactc   3720

cacctccacc tgtgggttcc caggcatgcc actgacctgc tgcatgaccc tgggtgagtc   3780

acaacccct                                                           3789


<210>  6089
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  6089

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Glu Lys Gln Arg Glu Leu Ala Arg Lys Gly Ser Leu 
        35                  40                  45


Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln Gln Pro Lys Lys Asn 
    50                  55                  60


Asn Val Met Ala Arg Thr Arg Leu Val Val Pro Asn Lys Gly Tyr Ser 
65                  70                  75                  80


Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu Val Ala Leu Asp Thr 
                85                  90                  95


Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr Ser Ser Ser Gly Tyr 
            100                 105                 110


Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn Ile Gln Leu Leu Lys 
        115                 120                 125


Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp Glu Asp Leu Asp Leu 
    130                 135                 140


Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met Cys Cys Gln Ala Thr 
145                 150                 155                 160


Ser Ser Thr Ala Cys His Ile Gln 
                165


<210>  6090
<211>  942
<212>  DNA
<213>  Homo sapiens

<400>  6090
catccagctg ctgaaggacg gctaccggtt agatgagatc cccgacgacg aggacctaga     60

cctcatcccc cccaagtccg tgaaccccac gtgcatgtgc tgccaggcca cgtcctccac    120

cgcctgccac attcagtagc gggcggggcc actgcggtcg ccggggcggg gccgccaagg    180

gccgggtagg acgggcagag gccgacccct tcccagctcg tctgcctgcc cccggccccg    240

cgcccctaca gccgccaacc tcgtataaca gtcattgctt cctcctatgg taggacgtgt    300

acctctgtgt gttcatggag ctggagaaac caaaactggg tctctctcca cccgggagct    360

gaggaggggt gggggccgtt tgttcagtta cctgggggaa cctcacccag caccctgccc    420

cgcttcccag ggctggccaa gagagaagac tggacggcag ggaggtcaac attaacgagt    480

ggggggatca caaagccagg ggcttggccc caccccagcg aagccatgaa ctcccaagcc    540

ccggcctcag cctaaccagg aaaggggctc ggagggagaa aggcccaggg cagtggggac    600

gggtcccagc acctcggagc ccccttcaca cgccccctac cggcccatgt ttctatttgc    660

atttccccct cctcagatgg gaagcctggc aaagctgccc aaccgggtag tgcccctcac    720

ccttcccctt gtagatactg ccttaacact ccctcctctc tcagctgtgg ctgccaccca    780

gccaggtttc tccgtgctca ctaatttatt tccaggaagg tgtgtggaag acatgagccg    840

tgtataatat tttttttaac attttcattg cagtattgac catcatcctt ggttgtgtat    900

cgtgtaacac aaataatgat attaaaagca tcaaacaagc ca                       942


<210>  6091
<211>  66
<212>  PRT
<213>  Homo sapiens

<400>  6091

Met Phe Leu Phe Ala Phe Pro Pro Pro Gln Met Gly Ser Leu Ala Lys 
1               5                   10                  15


Leu Pro Asn Arg Val Val Pro Leu Thr Leu Pro Leu Val Asp Thr Ala 
            20                  25                  30


Leu Thr Leu Pro Pro Leu Ser Ala Val Ala Ala Thr Gln Pro Gly Phe 
        35                  40                  45


Ser Val Leu Thr Asn Leu Phe Pro Gly Arg Cys Val Glu Asp Met Ser 
    50                  55                  60


Arg Val 
65


<210>  6092
<211>  1882
<212>  DNA
<213>  Homo sapiens

<400>  6092
gggtaaggtg ggccttacag acaggctgag gtttgggtgg tgtgatctgt cctaattggc     60

ccctcaccaa tgcatctatc tgtctgccac cagcccaccc caccctgccc ccaccctcac    120

ccacgcttct gctcattggt ctcaatccca gcctggaagc agggagtaag gctggactcc    180

aatggcccat tcccctcacc ccagcccaag acgtgggagg ctgcttccca gtaagaatcc    240

aggagcaagc tttggtgaat ccagtgggct gagtggctct atggatgtgg ttgtttggat    300

gtggtaggga gtgcttagca gaatgtgtgt gtatctctga ggctgtcagg gggtgggtgg    360

gtgtgtgtct ctgttggacc tgtctctcct cagtctattc ctgtcataga tgtgggtgtc    420

cctggtaggg aagtgcctgt gtggtctgtt tacagtgcag aaggcggctc agcagtgcaa    480

tgggctgaca gccttggacc gggagtcaga agcctgggtt ctggttgtag ctctggcccc    540

tccctgtgat cttcaacaag ccacttgctt tctctcgtct tcagtttcct caactagaaa    600

atgaacagca gctgaaatta tgttgaagat ccttttatac ctgaaagagt ttcttcatag    660

aaatttctgt ggtggggagg gggcaatctc tgtgtgtctc agtataccta aaggttgggg    720

tggggcggag ttgtgtgtct ctgtagaaag gcgaaggggc agttcctatc aggactgtgt    780

atgtctgagc acatgtggct ctgtttggga ttacgtgttt gtctgtgaat gtgtgtgtgt    840

gttggagggt tgtctattgt gtgtggctgt atagggtgtc tgtagatcaa gatgtgtata    900

cagctgcttc tgctattgct ggtttggggg aggggactgg aaagctgaga ctgaaaatca    960

agagggaaga ggtgggagct ggaatgggga gcaatgagag gagggagtga gactgttggc   1020

ttaggaaggg tggtacctct ccctgcatca tacccaggaa ctgccagctc caaaatattg   1080

gggtacagct caccaccccc cactccgcca acccattcct acctcctcta gtgcagggac   1140

ccaagttaga tgatgagaaa atgccaaaca aagggaggca aggacagaga aggtacctgc   1200

aggacccaca aggcccatac tggcccccat ctgaacccac ctctcccacc cagatcaaca   1260

tccccccaac ccctgtgccc ccatcatctg gaccccagag ccagccctcc cactaccacc   1320

accaccaccc cggggctcct tggctcacct ttctagaaca tgggtacctc ctctttttgg   1380

gggctcattt agactgctgc ctttgctgct gacttgcagt gtgactcggg cccattgttc   1440

aatctctgtg gccctgagac accagggaaa atctcccccc ccacaggaca tactagttcc   1500

ctggcaggca agggcttcca actgaggcag tgcatgtgtg gcagagagag gcaggaagct   1560

ggcagtggca gcttctgtgt ctagggaggg gtgtggctcc ctccttccct gtctgggagg   1620

ttggagggaa gaatctaggc cttagcttgc cctcctgcca cccttcccct tgtagatact   1680

gccttaacac tccctcctct ctcagctgtg gctgccaccc agccaggttt ctccgtgctc   1740

actaatttat ttccaggaag gtgtgtggaa gacatgagcc gtgtataata ttttttttaa   1800

cattttcatt gcagtattga ccatcatcct tggttgtgta tcgtgtaaca caaataatga   1860

tattaaaagc atcaaacaag cc                                            1882


<210>  6093
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  6093

Met Leu Lys Ile Leu Leu Tyr Leu Lys Glu Phe Leu His Arg Asn Phe 
1               5                   10                  15


Cys Gly Gly Glu Gly Ala Ile Ser Val Cys Leu Ser Ile Pro Lys Gly 
            20                  25                  30


Trp Gly Gly Ala Glu Leu Cys Val Ser Val Glu Arg Arg Arg Gly Ser 
        35                  40                  45


Ser Tyr Gln Asp Cys Val Cys Leu Ser Thr Cys Gly Ser Val Trp Asp 
    50                  55                  60


Tyr Val Phe Val Cys Glu Cys Val Cys Val Leu Glu Gly Cys Leu Leu 
65                  70                  75                  80


Cys Val Ala Val 



<210>  6094
<211>  3609
<212>  DNA
<213>  Homo sapiens

<400>  6094
gtcaccgcag tggctgagct gctgacagga ggcggcagcg gagtaggagg cgaggcaaga     60

cctgcggctc ggcccggcca cagccgcggt agtgctaggc aagcccacgg agtcacgccg    120

gcctcagcca gtctgcgaac ctctcgcccc cgcccacccc tgcatccgcc cggcccctgc    180

ccgcccgagt ggtccgggga ggcctagtct gcaccacccg ccgggctcct ggggccgccg    240

ccccgcgcgg tcctgtcggc gtccgcggcc gcgcccggcc cctggcccgc tcgcccgccg    300

gcaccatgat ggaggagatc gaccggttcc aggacccagc cgccgcctcc atctctgacg    360

gagactgtga cgcccgggag ggtgagtcag tagccatgaa ttacaaacca tccccgctcc    420

aagtgaagct ggagaagcag cgggagctgg cccggaaggg ctccctgaag aatggcagca    480

tgggtagccc tgtcaaccag caacccaaga agaacaatgt catggcccga acaaggctgg    540

tcgtccccaa taaaggctac tcctcacttg accagagccc tgatgagaag ccactggtag    600

cccttgacac ggacagcgat gatgactttg acatgtctag atactcctcc tccggctact    660

cctctgctga gcagatcaac caagatttga acatccagct gctgaaggac ggctaccggt    720

tagatgagat ccccgacgac gaggacctag acctcatccc ccccaagtcc gtgaacccca    780

cgtgcatgtg ctgccaggcc acgtcctcca ccgcctgcca cattcagtag cgggcggggc    840

cactgcggtc gccggggcgg ggccgccaag ggccgggtag gacgggcaga ggccgacccc    900

ttcccagctc gtctgcctgc ccccggcccc gcgcccctac agccgccaac ctcgtataac    960

agtcattgct tcctcctatg gtaggacgtg tacctctgtg tgttcatgga gctggagaaa   1020

ccaaaactgg gtctctctcc acccgggagc tgaggagggg tgggggccgt ttgttcagtt   1080

acctggggga acctcaccca gcaccctgcc ccgcttccca gggctggcca agagagaaga   1140

ctggacggca gggaggtcaa cattaacgag tggggggatc acaaagccag gggcttggcc   1200

ccaccccagc gaagccatga actcccaagc cccggcctca gcctaaccag gaaaggggct   1260

cggagggaga aaggcccagg gcagtgggga cgggtcccag cacctcggag cccccttcac   1320

acgcccccta ccggcccatg tttctatttg catttccccc tcctcagatg ggaagcctgg   1380

caaagctgcc caaccgggta gtgcccctca cccatcggat cactgccttc ttcctcctct   1440

tgccccattc acccgcttcc ttgcactctg ggagtggggc agggtaaggt gggccttaca   1500

gacaggctga ggtttgggtg gtgtgatctg tcctaattgg cccctcacca atgcatctat   1560

ctgtctgcca ccagcccacc ccaccctgcc cccaccctca cccacgcttc tgctcattgg   1620

tctcaatccc agcctggaag cagggagtaa ggctggactc caatggccca ttcccctcac   1680

cccagcccaa gacgtgggag gctgcttccc agtaagaatc caggagcaag ctttggtgaa   1740

tccagtgggc tgagtggctc tatggatgtg gttgtttgga tgtggtaggg agtgcttagc   1800

agaatgtgtg tgtatctctg aggctgtcag ggggtgggtg ggtgtgtgtc tctgttggac   1860

ctgtctctcc tcagtctatt cctgtcatag atgtgggtgt ccctggtagg gaagtgcctg   1920

tgtggtctgt ttacagtgca gaaggcggct cagcagtgca atgggctgac agccttggac   1980

cgggagtcag aagcctgggt tctggttgta gctctggccc ctccctgtga tcttcaacaa   2040

gccacttgct ttctctcgtc ttcagtttcc tcaactagaa aatgaacagc agctgaaatt   2100

atgttgaaga tccttttata cctgaaagag tttcttcata gaaatttctg tggtggggag   2160

ggggcaatct ctgtgtgtct cagtatacct aaaggttggg gtggggcgga gttgtgtgtc   2220

tctgtagaaa ggcgaagggg cagttcctat caggactgtg tatgtctgag cacatgtggc   2280

tctgtttggg attacgtgtt tgtctgtgaa tgtgtgtgtg tgttggaggg ttgtctattg   2340

tgtgtggctg tatagggtgt ctgtagatca agatgtgtat acagctgctt ctgctattgc   2400

tggtttgggg gaggggactg gaaagctgag actgaaaatc aagagggaag aggtgaggaa   2460

ggcccacccc tggggctggg cagtgtagac ctgccaccgt gtgaagaaaa atgaaagcac   2520

agatagccta agactgcaca ggcctgtgcc cacatacctt atagcacagg cccaggtgga   2580

tcatctcatg ctaacacccc acatgtgctg gtggatccac tcccatggat ccactcacat   2640

gctgcaggca tgcagtagac tcacccacag cccactctct ggacaccaat cctgggaggt   2700

gggagctgga atggggagca atgagaggag ggagtgagac tgttggctta ggaagggtgg   2760

tacctctccc tgcatcatac ccaggaactg ccagctccaa aatattgggg tacagctcac   2820

caccccccac tccgccaacc cattcctacc tcctctagtg cagggaccca agttagatga   2880

tgagaaaatg ccaaacaaag ggaggcaagg acagagaagg tacctgcagg acccacaagg   2940

cccatactgg cccccatctg aacccacctc tcccacccag atcaacatcc ccccaacccc   3000

tgtgccccca tcatctggac cccagagcca gccctcccac taccaccacc accaccccgg   3060

ggctccttgg ctcacctttc tagaacatgg gtacctcctc tttttggggg ctcatttaga   3120

ctgctgcctt tgctgctgac ttgcagtgtg actcgggccc attgttcaat ctctgtggcc   3180

ctgagacacc agggaaaatc tcccccccca caggacatac tagttccctg gcaggcaagg   3240

gcttccaact gaggcagtgc atgtgtggca gagagaggca ggaagctggc agtggcagct   3300

tctgtgtcta gggaggggtg tggctccctc cttccctgtc tgggaggttg gagggaagaa   3360

tctaggcctt agcttgccct cctgccaccc ttccccttgt agatactgcc ttaacactcc   3420

ctcctctctc agctgtggct gccacccagc caggtttctc cgtgctcact aatttatttc   3480

caggaaggtg tgtggaagac atgagccgtg tataatattt tttttaacat tttcattgca   3540

gtattgacca tcatccttgg ttgtgtatcg tgtaacacaa ataatgatat taaaagcatc   3600

aaacaagcc                                                           3609


<210>  6095
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  6095

Met Met Glu Glu Ile Asp Arg Phe Gln Asp Pro Ala Ala Ala Ser Ile 
1               5                   10                  15


Ser Asp Gly Asp Cys Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn 
            20                  25                  30


Tyr Lys Pro Ser Pro Leu Gln Val Lys Leu Glu Lys Gln Arg Glu Leu 
        35                  40                  45


Ala Arg Lys Gly Ser Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn 
    50                  55                  60


Gln Gln Pro Lys Lys Asn Asn Val Met Ala Arg Thr Arg Leu Val Val 
65                  70                  75                  80


Pro Asn Lys Gly Tyr Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro 
                85                  90                  95


Leu Val Ala Leu Asp Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg 
            100                 105                 110


Tyr Ser Ser Ser Gly Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu 
        115                 120                 125


Asn Ile Gln Leu Leu Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp 
    130                 135                 140


Asp Glu Asp Leu Asp Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys 
145                 150                 155                 160


Met Cys Cys Gln Ala Thr Ser Ser Thr Ala Cys His Ile Gln 
                165                 170


<210>  6096
<211>  3279
<212>  DNA
<213>  Homo sapiens

<400>  6096
gagtcaccgc agtggctgag ctgctgacag gaggcggcag cggagtagga ggcgaggcaa     60

gacctgcggc tcggcccggc cacagccgcg gtagtgctag gcaagcccac ggagtcacgc    120

cggcctcagc cagtctgcga acctctcgcc cccgcccacc cctgcatccg cccggcccct    180

gcccgcccga gtggtccggg gagcatgatg gaggagatcg accggttcca ggacccagcc    240

gccgcctcca tctctgacgg agactgtgac gcccgggagg agaagcagcg ggagctggcc    300

cggaagggct ccctgaagaa tggcagcatg ggtagccctg tcaaccagca acccaagaag    360

aacaatgtca tggcccgaac aaggctggtc gtccccaata aaggctactc ctcacttgac    420

cagagccctg atgagaagcc actggtagcc cttgacacgg acagcgatga tgactttgac    480

atgtctagat actcctcctc cggctactcc tctgctgagc agatcaacca agatttgaac    540

atccagctgc tgaaggacgg ctaccggtta gatgagatcc ccgacgacga ggacctagac    600

ctcatccccc ccaagtccgt gaaccccacg tgcatgtgct gccaggccac gtcctccacc    660

gcctgccaca ttcagtagcg ggcggggcca ctgcggtcgc cggggcgggg ccgccaaggg    720

ccgggtagga cgggcagagg ccgacccctt cccagctcgt ctgcctgccc ccggccccgc    780

gcccctacag ccgccaacct cgtataacag tcattgcttc ctcctatggt aggacgtgta    840

cctctgtgtg ttcatggagc tggagaaacc aaaactgggt ctctctccac ccgggagctg    900

aggaggggtg ggggccgttt gttcagttac ctgggggaac ctcacccagc accctgcccc    960

gcttcccagg gctggccaag agagaagact ggacggcagg gaggtcaaca ttaacgagtg   1020

gggggatcac aaagccaggg gcttggcccc accccagcga agccatgaac tcccaagccc   1080

cggcctcagc ctaaccagga aaggggctcg gagggagaaa ggcccagggc agtggggacg   1140

ggtcccagca cctcggagcc cccttcacac gccccctacc ggcccatgtt tctatttgca   1200

tttccccctc ctcagatggg aagcctggca aagctgccca accgggtagt gcccctcacc   1260

catcggatca ctgccttctt cctcctcttg ccccattcac ccgcttcctt gcactctggg   1320

agtggggcag ggtaaggtgg gccttacaga caggctgagg tttgggtggt gtgatctgtc   1380

ctaattggcc cctcaccaat gcatctatct gtctgccacc agcccacccc accctgcccc   1440

caccctcacc cacgcttctg ctcattggtc tcaatcccag cctggaagca gggagtaagg   1500

ctggactcca atggcccatt cccctcaccc cagcccaaga cgtgggaggc tgcttcccag   1560

taagaatcca ggagcaagct ttggtgaatc cagtgggctg agtggctcta tggatgtggt   1620

tgtttggatg tggtagggag tgcttagcag aatgtgtgtg tatctctgag gctgtcaggg   1680

ggtgggtggg tgtgtgtctc tgttggacct gtctctcctc agtctattcc tgtcatagat   1740

gtgggtgtcc ctggtaggga agtgcctgtg tggtctgttt acagtgtata cctgaaagag   1800

tttcttcata gaaatttctg tggtggggag ggggcaatct ctgtgtgtct cagtatacct   1860

aaaggttggg gtggggcgga gttgtgtgtc tctgtagaaa ggcgaagggg cagttcctat   1920

caggactgtg tatgtctgag cacatgtggc tctgtttggg attacgtgtt tgtctgtgaa   1980

tgtgtgtgtg tgttggaggg ttgtctattg tgtgtggctg tatagggtgt ctgtagatca   2040

agatgtgtat acagctgctt ctgctattgc tggtttgggg gaggggactg gaaagctgag   2100

actgaaaatc aagagggaag aggtgaggaa ggcccacccc tggggctggg cagtgtagac   2160

ctgccaccgt gtgaagaaaa atgaaagcac agatagccta agactgcaca ggcctgtgcc   2220

cacatacctt atagcacagg cccaggtgga tcatctcatg ctaacacccc acatgtgctg   2280

gtggatccac tcccatggat ccactcacat gctgcaggca tgcagtagac tcacccacag   2340

cccactctct ggacaccaat cctgggaggt gggagctgga atggggagca atgagaggag   2400

ggagtgagac tgttggctta ggaagggtgg tacctctccc tgcatcatac ccaggaactg   2460

ccagctccaa aatattgggg tacagctcac caccccccac tccgccaacc cattcctacc   2520

tcctctagtg cagggaccca agttagatga tgagaaaatg ccaaacaaag ggaggcaagg   2580

acagagaagg tacctgcagg acccacaagg cccatactgg cccccatctg aacccacctc   2640

tcccacccag atcaacatcc ccccaacccc tgtgccccca tcatctggac cccagagcca   2700

gccctcccac taccaccacc accaccccgg ggctccttgg ctcacctttc tagaacatgg   2760

gtacctcctc tttttggggg ctcatttaga ctgctgcctt tgctgctgac ttgcagtgtg   2820

actcgggccc attgttcaat ctctgtggcc ctgagacacc agggaaaatc tcccccccca   2880

caggacatac tagttccctg gcaggcaagg gcttccaact gaggcagtgc atgtgtggca   2940

gagagaggca ggaagctggc agtggcagct tctgtgtcta gggaggggtg tggctccctc   3000

cttccctgtc tgggaggttg gagggaagaa tctaggcctt agcttgccct cctgccaccc   3060

ttccccttgt agatactgcc ttaacactcc ctcctctctc agctgtggct gccacccagc   3120

caggtttctc cgtgctcact aatttatttc caggaaggtg tgtggaagac atgagccgtg   3180

tataatattt tttttaacat tttcattgca gtattgacca tcatccttgg ttgtgtatcg   3240

tgtaacacaa ataatgatat taaaagcatc aaacaagcc                          3279


<210>  6097
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  6097

Met Met Glu Glu Ile Asp Arg Phe Gln Asp Pro Ala Ala Ala Ser Ile 
1               5                   10                  15


Ser Asp Gly Asp Cys Asp Ala Arg Glu Glu Lys Gln Arg Glu Leu Ala 
            20                  25                  30


Arg Lys Gly Ser Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln 
        35                  40                  45


Gln Pro Lys Lys Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro 
    50                  55                  60


Asn Lys Gly Tyr Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu 
65                  70                  75                  80


Val Ala Leu Asp Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr 
                85                  90                  95


Ser Ser Ser Gly Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn 
            100                 105                 110


Ile Gln Leu Leu Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp 
        115                 120                 125


Glu Asp Leu Asp Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met 
    130                 135                 140


Cys Cys Gln Ala Thr Ser Ser Thr Ala Cys His Ile Gln 
145                 150                 155


<210>  6098
<211>  1738
<212>  DNA
<213>  Homo sapiens

<400>  6098
gagtcaccgc agtggctgag ctgctgacag gaggcggcag cggagtagga ggcgaggcaa     60

gacctgcggc tcggcccggc cacagccgcg gtagtgctag gcaagcccac ggagtcacgc    120

cggcctcagc cagtctgcga acctctcgcc cccgcccacc cctgcatccg cccggcccct    180

gcccgcccga gtggtccggg gaggcctagt ctgcaccacc cgccgggctc ctggggccgc    240

cgccccgcgc ggtcctgtcg gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc    300

cggcaccatg atggaggaga tcgaccggtt ccaggtgccc accgcgcact cggagatgca    360

gccgctggac ccagccgccg cctccatctc tgacggagac tgtgacgccc gggagggtga    420

gtcagtagcc atgaattaca aaccatcccc gctccaagtg aagctgggtg agtgtgttgt    480

atagggtgtc tgtagatcaa gatgtgtata cagctgcttc tgctattgct ggtttggggg    540

aggggactgg aaagctgaga ctgaaaatca agagggaaga ggtgaggaag gcccacccct    600

ggggctgggc agtgtagacc tgccaccgtg tgaagaaaaa tgaaagcaca gatagcctaa    660

gactgcacag gcctgtgccc acatacctta tagcacaggc ccaggtggat catctcatgc    720

taacacccca catgtgctgg tggatccact cccatggatc cactcacatg ctgcaggcat    780

gcagtagact cacccacagc ccactctctg gacaccaatc ctgggaggtg ggagctggaa    840

tggggagcaa tgagaggagg gagtgagact gttggcttag gaagggtggt acctctccct    900

gcatcatacc caggaactgc cagctccaaa atattggggt acagctcacc accccccact    960

ccgccaaccc attcctacct cctctagtgc agggacccaa gttagatgat gagaaaatgc   1020

caaacaaagg gaggcaagga cagagaaggt acctgcagga cccacaaggc ccatactggc   1080

ccccatctga acccacctct cccacccaga tcaacatccc cccaacccct gtgcccccat   1140

catctggacc ccagagccag ccctcccact accaccacca ccaccccggg gctccttggc   1200

tcacctttct agaacatggg tacctcctct ttttgggggc tcatttagac tgctgccttt   1260

gctgctgact tgcagtgtga ctcgggccca ttgttcaatc tctgtggccc tgagacacca   1320

gggaaaatct ccccccccac aggacatact agttccctgg caggcaaggg cttccaactg   1380

aggcagtgca tgtgtggcag agagaggcag gaagctggca gtggcagctt ctgtgtctag   1440

ggaggggtgt ggctccctcc ttccctgtct gggaggttgg agggaagaat ctaggcctta   1500

gcttgccctc ctgccaccct tccccttgta gatactgcct taacactccc tcctctctca   1560

gctgtggctg ccacccagcc aggtttctcc gtgctcacta atttatttcc aggaaggtgt   1620

gtggaagaca tgagccgtgt ataatatttt ttttaacatt ttcattgcag tattgaccat   1680

catccttggt tgtgtatcgt gtaacacaaa taatgatatt aaaagcatca aacaagcc     1738


<210>  6099
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  6099

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn Tyr Lys Pro Ser Pro 
        35                  40                  45


Leu Gln Val Lys Leu Gly Glu Cys Val Val 
    50                  55


<210>  6100
<211>  3684
<212>  DNA
<213>  Homo sapiens

<400>  6100
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggtgccc accgcgcact cggagatgca gccgctggac ccagccgccg    420

cctccatctc tgacggagac tgtgacgccc gggagggtga gtcagtagcc atgaattaca    480

aaccatcccc gctccaagtg aagctggaga agcagcggga gctggcccgg aagggctccc    540

tgaagaatgg cagcatgggt agccctgtca accagcaacc caagaagaac aatgtcatgg    600

cccgaacaag gctggtcgtc cccaataaag gctactcctc acttgaccag agccctgatg    660

agaagccact ggtagccctt gacacggaca gcgatgatga ctttgacatg tctagatact    720

cctcctccgg ctactcctct gctgagcaga tcaaccaaga tttgaacatc cagctgctga    780

aggacggcta ccggttagat gagatccccg acgacgagga cctagacctc atccccccca    840

agtccgtgaa ccccacgtgc atgtgctgcc aggccacgtc ctccaccgcc tgccacattc    900

agtagcgggc ggggccactg cggtcgccgg ggcggggccg ccaagggccg ggtaggacgg    960

gcagaggccg accccttccc agctcgtctg cctgcccccg gccccgcgcc cctacagccg   1020

ccaacctcgt ataacagtca ttgcttcctc ctatggtagg acgtgtacct ctgtgtgttc   1080

atggagctgg agaaaccaaa actgggtctc tctccacccg ggagctgagg aggggtgggg   1140

gccgtttgtt cagttacctg ggggaacctc acccagcacc ctgccccgct tcccagggct   1200

ggccaagaga gaagactgga cggcagggag gtcaacatta acgagtgggg ggatcacaaa   1260

gccaggggct tggccccacc ccagcgaagc catgaactcc caagccccgg cctcagccta   1320

accaggaaag gggctcggag ggagaaaggc ccagggcagt ggggacgggt cccagcacct   1380

cggagccccc ttcacacgcc ccctaccggc ccatgtttct atttgcattt ccccctcctc   1440

agatgggaag cctggcaaag ctgcccaacc gggtagtgcc cctcacccat cggatcactg   1500

ccttcttcct cctcttgccc cattcacccg cttccttgca ctctgggagt ggggcagggt   1560

aaggtgggcc ttacagacag gctgaggttt gggtggtgtg atctgtccta attggcccct   1620

caccaatgca tctatctgtc tgccaccagc ccaccccacc ctgcccccac cctcacccac   1680

gcttctgctc attggtctca atcccagcct ggaagcaggg agtaaggctg gactccaatg   1740

gcccattccc ctcaccccag cccaagacgt gggaggctgc ttcccagtaa gaatccagga   1800

gcaagctttg gtgaatccag tgggctgagt ggctctatgg atgtggttgt ttggatgtgg   1860

tagggagtgc ttagcagaat gtgtgtgtat ctctgaggct gtcagggggt gggtgggtgt   1920

gtgtctctgt tggacctgtc tctcctcagt ctattcctgt catagatgtg ggtgtccctg   1980

gtagggaagt gcctgtgtgg tctgtttaca gtgcagaagg cggctcagca gtgcaatggg   2040

ctgacagcct tggaccggga gtcagaagcc tgggttctgg ttgtagctct ggcccctccc   2100

tgtgatcttc aacaagccac ttgctttctc tcgtcttcag tttcctcaac tagaaaatga   2160

acagcagctg aaattatgtt gaagatcctt ttatacctga aagagtttct tcatagaaat   2220

ttctgtggtg gggagggggc aatctctgtg tgtctcagta tacctaaagg ttggggtggg   2280

gcggagttgt gtgtctctgt agaaaggcga aggggcagtt cctatcagga ctgtgtatgt   2340

ctgagcacat gtggctctgt ttgggattac gtgtttgtct gtgaatgtgt gtgtgtgttg   2400

gagggttgtc tattgtgtgt ggctgtatag ggtgtctgta gatcaagatg tgtatacagc   2460

tgcttctgct attgctggtt tgggggaggg gactggaaag ctgagactga aaatcaagag   2520

ggaagaggtg aggaaggccc acccctgggg ctgggcagtg tagacctgcc accgtgtgaa   2580

gaaaaatgaa agcacagata gcctaagact gcacaggcct gtgcccacat accttatagc   2640

acaggcccag gtggatcatc tcatgctaac accccacatg tgctggtgga tccactccca   2700

tggatccact cacatgctgc aggcatgcag tagactcacc cacagcccac tctctggaca   2760

ccaatcctgg gaggtgggag ctggaatggg gagcaatgag aggagggagt gagactgttg   2820

gcttaggaag ggtggtacct ctccctgcat catacccagg aactgccagc tccaaaatat   2880

tggggtacag ctcaccaccc cccactccgc caacccattc ctacctcctc tagtgcaggg   2940

acccaagtta gatgatgaga aaatgccaaa caaagggagg caaggacaga gaaggtacct   3000

gcaggaccca caaggcccat actggccccc atctgaaccc acctctccca cccagatcaa   3060

catcccccca acccctgtgc ccccatcatc tggaccccag agccagccct cccactacca   3120

ccaccaccac cccggggctc cttggctcac ctttctagaa catgggtacc tcctcttttt   3180

gggggctcat ttagactgct gcctttgctg ctgacttgca gtgtgactcg ggcccattgt   3240

tcaatctctg tggccctgag acaccaggga aaatctcccc ccccacagga catactagtt   3300

ccctggcagg caagggcttc caactgaggc agtgcatgtg tggcagagag aggcaggaag   3360

ctggcagtgg cagcttctgt gtctagggag gggtgtggct ccctccttcc ctgtctggga   3420

ggttggaggg aagaatctag gccttagctt gccctcctgc cacccttccc cttgtagata   3480

ctgccttaac actccctcct ctctcagctg tggctgccac ccagccaggt ttctccgtgc   3540

tcactaattt atttccagga aggtgtgtgg aagacatgag ccgtgtataa tatttttttt   3600

aacattttca ttgcagtatt gaccatcatc cttggttgtg tatcgtgtaa cacaaataat   3660

gatattaaaa gcatcaaaca agcc                                          3684


<210>  6101
<211>  185
<212>  PRT
<213>  Homo sapiens

<400>  6101

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn Tyr Lys Pro Ser Pro 
        35                  40                  45


Leu Gln Val Lys Leu Glu Lys Gln Arg Glu Leu Ala Arg Lys Gly Ser 
    50                  55                  60


Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln Gln Pro Lys Lys 
65                  70                  75                  80


Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro Asn Lys Gly Tyr 
                85                  90                  95


Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu Val Ala Leu Asp 
            100                 105                 110


Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr Ser Ser Ser Gly 
        115                 120                 125


Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn Ile Gln Leu Leu 
    130                 135                 140


Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp Glu Asp Leu Asp 
145                 150                 155                 160


Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met Cys Cys Gln Ala 
                165                 170                 175


Thr Ser Ser Thr Ala Cys His Ile Gln 
            180                 185


<210>  6102
<211>  3600
<212>  DNA
<213>  Homo sapiens

<400>  6102
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggaccca gccgccgcct ccatctctga cggagactgt gacgcccggg    420

aggagaagca gcgggagctg gcccggaagg gctccctgaa gaatggcagc atgggtagcc    480

ctgtcaacca gcaacccaag aagaacaatg tcatggcccg aacaaggctg gtcgtcccca    540

ataaaggcta ctcctcactt gaccagagcc ctgatgagaa gccactggta gcccttgaca    600

cggacagcga tgatgacttt gacatgtcta gatactcctc ctccggctac tcctctgctg    660

agcagatcaa ccaagatttg aacatccagc tgctgaagga cggctaccgg ttagatgaga    720

tccccgacga cgaggaccta gacctcatcc cccccaagtc cgtgaacccc acgtgcatgt    780

gctgccaggc cacgtcctcc accgcctgcc acattcagta gcgggcgggg ccactgcggt    840

cgccggggcg gggccgccaa gggccgggta ggacgggcag aggccgaccc cttcccagct    900

cgtctgcctg cccccggccc cgcgccccta cagccgccaa cctcgtataa cagtcattgc    960

ttcctcctat ggtaggacgt gtacctctgt gtgttcatgg agctggagaa accaaaactg   1020

ggtctctctc cacccgggag ctgaggaggg gtgggggccg tttgttcagt tacctggggg   1080

aacctcaccc agcaccctgc cccgcttccc agggctggcc aagagagaag actggacggc   1140

agggaggtca acattaacga gtggggggat cacaaagcca ggggcttggc cccaccccag   1200

cgaagccatg aactcccaag ccccggcctc agcctaacca ggaaaggggc tcggagggag   1260

aaaggcccag ggcagtgggg acgggtccca gcacctcgga gcccccttca cacgccccct   1320

accggcccat gtttctattt gcatttcccc ctcctcagat gggaagcctg gcaaagctgc   1380

ccaaccgggt agtgcccctc acccatcgga tcactgcctt cttcctcctc ttgccccatt   1440

cacccgcttc cttgcactct gggagtgggg cagggtaagg tgggccttac agacaggctg   1500

aggtttgggt ggtgtgatct gtcctaattg gcccctcacc aatgcatcta tctgtctgcc   1560

accagcccac cccaccctgc ccccaccctc acccacgctt ctgctcattg gtctcaatcc   1620

cagcctggaa gcagggagta aggctggact ccaatggccc attcccctca ccccagccca   1680

agacgtggga ggctgcttcc cagtaagaat ccaggagcaa gctttggtga atccagtggg   1740

ctgagtggct ctatggatgt ggttgtttgg atgtggtagg gagtgcttag cagaatgtgt   1800

gtgtatctct gaggctgtca gggggtgggt gggtgtgtgt ctctgttgga cctgtctctc   1860

ctcagtctat tcctgtcata gatgtgggtg tccctggtag ggaagtgcct gtgtggtctg   1920

tttacagtgc agaaggcggc tcagcagtgc aatgggctga cagccttgga ccgggagtca   1980

gaagcctggg ttctggttgt agctctggcc cctccctgtg atcttcaaca agccacttgc   2040

tttctctcgt cttcagtttc ctcaactaga aaatgaacag cagctgaaat tatgttgaag   2100

atccttttat acctgaaaga gtttcttcat agaaatttct gtggtgggga gggggcaatc   2160

tctgtgtgtc tcagtatacc taaaggttgg ggtggggcgg agttgtgtgt ctctgtagaa   2220

aggcgaaggg gcagttccta tcaggactgt gtatgtctga gcacatgtgg ctctgtttgg   2280

gattacgtgt ttgtctgtga atgtgtgtgt gtgttggagg gttgtctatt gtgtgtggct   2340

gtatagggtg tctgtagatc aagatgtgta tacagctgct tctgctattg ctggtttggg   2400

ggaggggact ggaaagctga gactgaaaat caagagggaa gaggtgagga aggcccaccc   2460

ctggggctgg gcagtgtaga cctgccaccg tgtgaagaaa aatgaaagca cagatagcct   2520

aagactgcac aggcctgtgc ccacatacct tatagcacag gcccaggtgg atcatctcat   2580

gctaacaccc cacatgtgct ggtggatcca ctcccatgga tccactcaca tgctgcaggc   2640

atgcagtaga ctcacccaca gcccactctc tggacaccaa tcctgggagg tgggagctgg   2700

aatggggagc aatgagagga gggagtgaga ctgttggctt aggaagggtg gtacctctcc   2760

ctgcatcata cccaggaact gccagctcca aaatattggg gtacagctca ccacccccca   2820

ctccgccaac ccattcctac ctcctctagt gcagggaccc aagttagatg atgagaaaat   2880

gccaaacaaa gggaggcaag gacagagaag gtacctgcag gacccacaag gcccatactg   2940

gcccccatct gaacccacct ctcccaccca gatcaacatc cccccaaccc ctgtgccccc   3000

atcatctgga ccccagagcc agccctccca ctaccaccac caccaccccg gggctccttg   3060

gctcaccttt ctagaacatg ggtacctcct ctttttgggg gctcatttag actgctgcct   3120

ttgctgctga cttgcagtgt gactcgggcc cattgttcaa tctctgtggc cctgagacac   3180

cagggaaaat ctcccccccc acaggacata ctagttccct ggcaggcaag ggcttccaac   3240

tgaggcagtg catgtgtggc agagagaggc aggaagctgg cagtggcagc ttctgtgtct   3300

agggaggggt gtggctccct ccttccctgt ctgggaggtt ggagggaaga atctaggcct   3360

tagcttgccc tcctgccacc cttccccttg tagatactgc cttaacactc cctcctctct   3420

cagctgtggc tgccacccag ccaggtttct ccgtgctcac taatttattt ccaggaaggt   3480

gtgtggaaga catgagccgt gtataatatt ttttttaaca ttttcattgc agtattgacc   3540

atcatccttg gttgtgtatc gtgtaacaca aataatgata ttaaaagcat caaacaagcc   3600


<210>  6103
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  6103

Met Met Glu Glu Ile Asp Arg Phe Gln Asp Pro Ala Ala Ala Ser Ile 
1               5                   10                  15


Ser Asp Gly Asp Cys Asp Ala Arg Glu Glu Lys Gln Arg Glu Leu Ala 
            20                  25                  30


Arg Lys Gly Ser Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln 
        35                  40                  45


Gln Pro Lys Lys Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro 
    50                  55                  60


Asn Lys Gly Tyr Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu 
65                  70                  75                  80


Val Ala Leu Asp Thr Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr 
                85                  90                  95


Ser Ser Ser Gly Tyr Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn 
            100                 105                 110


Ile Gln Leu Leu Lys Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp 
        115                 120                 125


Glu Asp Leu Asp Leu Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met 
    130                 135                 140


Cys Cys Gln Ala Thr Ser Ser Thr Ala Cys His Ile Gln 
145                 150                 155


<210>  6104
<211>  3633
<212>  DNA
<213>  Homo sapiens

<400>  6104
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggtgccc accgcgcact cggagatgca gccgctggac ccagccgccg    420

cctccatctc tgacggagac tgtgacgccc gggaggagaa gcagcgggag ctggcccgga    480

agggctccct gaagaatggc agcatgggta gccctgtcaa ccagcaaccc aagaagaaca    540

atgtcatggc ccgaacaagg ctggtcgtcc ccaataaagg ctactcctca cttgaccaga    600

gccctgatga gaagccactg gtagcccttg acacggacag cgatgatgac tttgacatgt    660

ctagatactc ctcctccggc tactcctctg ctgagcagat caaccaagat ttgaacatcc    720

agctgctgaa ggacggctac cggttagatg agatccccga cgacgaggac ctagacctca    780

tcccccccaa gtccgtgaac cccacgtgca tgtgctgcca ggccacgtcc tccaccgcct    840

gccacattca gtagcgggcg gggccactgc ggtcgccggg gcggggccgc caagggccgg    900

gtaggacggg cagaggccga ccccttccca gctcgtctgc ctgcccccgg ccccgcgccc    960

ctacagccgc caacctcgta taacagtcat tgcttcctcc tatggtagga cgtgtacctc   1020

tgtgtgttca tggagctgga gaaaccaaaa ctgggtctct ctccacccgg gagctgagga   1080

ggggtggggg ccgtttgttc agttacctgg gggaacctca cccagcaccc tgccccgctt   1140

cccagggctg gccaagagag aagactggac ggcagggagg tcaacattaa cgagtggggg   1200

gatcacaaag ccaggggctt ggccccaccc cagcgaagcc atgaactccc aagccccggc   1260

ctcagcctaa ccaggaaagg ggctcggagg gagaaaggcc cagggcagtg gggacgggtc   1320

ccagcacctc ggagccccct tcacacgccc cctaccggcc catgtttcta tttgcatttc   1380

cccctcctca gatgggaagc ctggcaaagc tgcccaaccg ggtagtgccc ctcacccatc   1440

ggatcactgc cttcttcctc ctcttgcccc attcacccgc ttccttgcac tctgggagtg   1500

gggcagggta aggtgggcct tacagacagg ctgaggtttg ggtggtgtga tctgtcctaa   1560

ttggcccctc accaatgcat ctatctgtct gccaccagcc caccccaccc tgcccccacc   1620

ctcacccacg cttctgctca ttggtctcaa tcccagcctg gaagcaggga gtaaggctgg   1680

actccaatgg cccattcccc tcaccccagc ccaagacgtg ggaggctgct tcccagtaag   1740

aatccaggag caagctttgg tgaatccagt gggctgagtg gctctatgga tgtggttgtt   1800

tggatgtggt agggagtgct tagcagaatg tgtgtgtatc tctgaggctg tcagggggtg   1860

ggtgggtgtg tgtctctgtt ggacctgtct ctcctcagtc tattcctgtc atagatgtgg   1920

gtgtccctgg tagggaagtg cctgtgtggt ctgtttacag tgcagaaggc ggctcagcag   1980

tgcaatgggc tgacagcctt ggaccgggag tcagaagcct gggttctggt tgtagctctg   2040

gcccctccct gtgatcttca acaagccact tgctttctct cgtcttcagt ttcctcaact   2100

agaaaatgaa cagcagctga aattatgttg aagatccttt tatacctgaa agagtttctt   2160

catagaaatt tctgtggtgg ggagggggca atctctgtgt gtctcagtat acctaaaggt   2220

tggggtgggg cggagttgtg tgtctctgta gaaaggcgaa ggggcagttc ctatcaggac   2280

tgtgtatgtc tgagcacatg tggctctgtt tgggattacg tgtttgtctg tgaatgtgtg   2340

tgtgtgttgg agggttgtct attgtgtgtg gctgtatagg gtgtctgtag atcaagatgt   2400

gtatacagct gcttctgcta ttgctggttt gggggagggg actggaaagc tgagactgaa   2460

aatcaagagg gaagaggtga ggaaggccca cccctggggc tgggcagtgt agacctgcca   2520

ccgtgtgaag aaaaatgaaa gcacagatag cctaagactg cacaggcctg tgcccacata   2580

ccttatagca caggcccagg tggatcatct catgctaaca ccccacatgt gctggtggat   2640

ccactcccat ggatccactc acatgctgca ggcatgcagt agactcaccc acagcccact   2700

ctctggacac caatcctggg aggtgggagc tggaatgggg agcaatgaga ggagggagtg   2760

agactgttgg cttaggaagg gtggtacctc tccctgcatc atacccagga actgccagct   2820

ccaaaatatt ggggtacagc tcaccacccc ccactccgcc aacccattcc tacctcctct   2880

agtgcaggga cccaagttag atgatgagaa aatgccaaac aaagggaggc aaggacagag   2940

aaggtacctg caggacccac aaggcccata ctggccccca tctgaaccca cctctcccac   3000

ccagatcaac atccccccaa cccctgtgcc cccatcatct ggaccccaga gccagccctc   3060

ccactaccac caccaccacc ccggggctcc ttggctcacc tttctagaac atgggtacct   3120

cctctttttg ggggctcatt tagactgctg cctttgctgc tgacttgcag tgtgactcgg   3180

gcccattgtt caatctctgt ggccctgaga caccagggaa aatctccccc cccacaggac   3240

atactagttc cctggcaggc aagggcttcc aactgaggca gtgcatgtgt ggcagagaga   3300

ggcaggaagc tggcagtggc agcttctgtg tctagggagg ggtgtggctc cctccttccc   3360

tgtctgggag gttggaggga agaatctagg ccttagcttg ccctcctgcc acccttcccc   3420

ttgtagatac tgccttaaca ctccctcctc tctcagctgt ggctgccacc cagccaggtt   3480

tctccgtgct cactaattta tttccaggaa ggtgtgtgga agacatgagc cgtgtataat   3540

atttttttta acattttcat tgcagtattg accatcatcc ttggttgtgt atcgtgtaac   3600

acaaataatg atattaaaag catcaaacaa gcc                                3633


<210>  6105
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  6105

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Glu Lys Gln Arg Glu Leu Ala Arg Lys Gly Ser Leu 
        35                  40                  45


Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln Gln Pro Lys Lys Asn 
    50                  55                  60


Asn Val Met Ala Arg Thr Arg Leu Val Val Pro Asn Lys Gly Tyr Ser 
65                  70                  75                  80


Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu Val Ala Leu Asp Thr 
                85                  90                  95


Asp Ser Asp Asp Asp Phe Asp Met Ser Arg Tyr Ser Ser Ser Gly Tyr 
            100                 105                 110


Ser Ser Ala Glu Gln Ile Asn Gln Asp Leu Asn Ile Gln Leu Leu Lys 
        115                 120                 125


Asp Gly Tyr Arg Leu Asp Glu Ile Pro Asp Asp Glu Asp Leu Asp Leu 
    130                 135                 140


Ile Pro Pro Lys Ser Val Asn Pro Thr Cys Met Cys Cys Gln Ala Thr 
145                 150                 155                 160


Ser Ser Thr Ala Cys His Ile Gln 
                165


<210>  6106
<211>  1090
<212>  DNA
<213>  Homo sapiens

<400>  6106
aagatccggg cggtgtcccg gacccggaag tggagttgcc gagtcaccgc agtggctgag     60

ctgctgacag gaggcggcag cggagtagga ggcgaggcaa gacctgcggc tcggcccggc    120

cacagccgcg gtagtgctag gcaagcccac ggagtcacgc cggcctcagc cagtctgcga    180

acctctcgcc cccgcccacc cctgcatccg cccggcccct gcccgcccga gtggtccggg    240

gaggcctagt ctgcaccacc cgccgggctc ctggggccgc cgccccgcgc ggtcctgtcg    300

gcgtccgcgg ccgcgcccgg cccctggccc gctcgcccgc cggcaccatg atggaggaga    360

tcgaccggtt ccaggtgccc accgcgcact cggagatgca gccgctggac ccagccgccg    420

cctccatctc tgacggagac tgtgacgccc gggagggtga gtcagtagcc atgaattaca    480

aaccatcccc gctccaagtg aagctggaga agcagcggga gctggcccgg aagggctccc    540

tgaagaatgg cagcatgggt agccctgtca accagcaacc caagaagaac aatgtcatgg    600

cccgaacaag gctggtcgtc cccaataaag gctactcctc acttgaccag agccctgatg    660

agaagccact ggtagccctt gacacggaca ggtgtgtatg ggggcttggg ggtagctggg    720

cagcccaaag gaacctgtat agcacaagtg ggctgtacag gccacacctg ctatattgtc    780

agaattggga tattcttcag ccagaatctc tccaagggtg aattctccag ggatgggaat    840

ttttttacac cagggactgg gggttgaaga gaggtggcag agagaggaaa ggggggcctg    900

cgttgtctgc tgtcatcctg ggacaactga tccaatggtt gtccctaatt ggcctgtgat    960

gttgtctctg gacagcagaa tatgatgctt aatgccccat cccctcagga aggagcccta   1020

ctccctggaa aacacctggc tagacttgga ctttgggaat atcctacaag tcagggtgat   1080

ttgagtctac                                                          1090


<210>  6107
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  6107

Met Met Glu Glu Ile Asp Arg Phe Gln Val Pro Thr Ala His Ser Glu 
1               5                   10                  15


Met Gln Pro Leu Asp Pro Ala Ala Ala Ser Ile Ser Asp Gly Asp Cys 
            20                  25                  30


Asp Ala Arg Glu Gly Glu Ser Val Ala Met Asn Tyr Lys Pro Ser Pro 
        35                  40                  45


Leu Gln Val Lys Leu Glu Lys Gln Arg Glu Leu Ala Arg Lys Gly Ser 
    50                  55                  60


Leu Lys Asn Gly Ser Met Gly Ser Pro Val Asn Gln Gln Pro Lys Lys 
65                  70                  75                  80


Asn Asn Val Met Ala Arg Thr Arg Leu Val Val Pro Asn Lys Gly Tyr 
                85                  90                  95


Ser Ser Leu Asp Gln Ser Pro Asp Glu Lys Pro Leu Val Ala Leu Asp 
            100                 105                 110


Thr Asp Arg Cys Val Trp Gly Leu Gly Gly Ser Trp Ala Ala Gln Arg 
        115                 120                 125


Asn Leu Tyr Ser Thr Ser Gly Leu Tyr Arg Pro His Leu Leu Tyr Cys 
    130                 135                 140


Gln Asn Trp Asp Ile Leu Gln Pro Glu Ser Leu Gln Gly 
145                 150                 155


<210>  6108
<211>  3198
<212>  DNA
<213>  Homo sapiens

<400>  6108
gggggcgggg ccttgccgct gcggaggccg gagacgcggc ggcgctggac gcggaggcgc     60

tgggcgcacg gcgcggagcc ggccggagct cgaggccggc ggcggcggga gagcgacccg    120

ggcggcctcg tagcggggcc ccggatcccc gagtggcggc cggagcctcg aaaagagatt    180

ctcagcgctg attttgagat gatgggcttg ggaaacgggc gtcgcagcat gaagtcgccg    240

cccctcgtgc tggccgccct ggtggcctgc atcatcgtct tgggcttcaa ctactggatt    300

gcgagctccc ggagcgtgga cctccagaca cggatcatgg agctggaagg cagggtccgc    360

agggcggctg cagagagagg cgccgtggag ctgaagaaga acgagttcca gggagagctg    420

gagaagcagc gggagcagct tgacaaaatc cagtccagcc acaacttcca gctggagagc    480

gtcaacaagc tgtaccagga cgaaaaggcg gttttggtga ataacatcac cacaggtgag    540

aggctcatcc gagtgctgca agaccagtta aagaccctgc agaggaatta cggcaggctg    600

cagcaggatg tcctccagtt tcagaagaac cagaccaacc tggagaggaa gttctcctac    660

gacctgagcc agtgcatcaa tcagatgaag gaggtgaagg aacagtgtga ggagcgaata    720

gaagaggtca ccaaaaaggg gaatgaagct gtagcttcca gagacctgag tgaaaacaac    780

gaccagagac agcagctcca agccctcagt gagcctcagc ccaggctgca ggcagcaggc    840

ctgccacaca cagaggtgcc acaagggaag ggaaacgtgc ttggtaacag caagtcccag    900

acaccagccc ccagttccga agtggttttg gattcaaaga gacaagttga gaaagaggaa    960

accaatgaga tccaggtggt gaatgaggag cctcagaggg acaggctgcc gcaggagcca   1020

ggccgggagc aggtggtgga agacagacct gtaggtggaa gaggcttcgg gggagccgga   1080

gaactgggcc agaccccaca ggtgcaggct gccctgtcag tgagccagga aaatccagag   1140

atggagggcc ctgagcgaga ccagcttgtc atccccgacg gacaggagga ggagcaggaa   1200

gctgccgggg aagggagaaa ccagcagaaa ctgagaggag aagatgacta caacatggat   1260

gaaaatgaag cagaatctga gacagacaag caagcagccc tggcagggaa tgacagaaac   1320

atagatgttt ttaatgttga agatcagaaa agagacacca taaatttact tgatcagcgt   1380

gaaaagcgga atcatacact ctgaattgaa ctggaatcac atatttcaca acagggccga   1440

agagatgact ataaaatgtt catgagggac tgaatactga aaactgtgaa atgtactaaa   1500

taaaatgtac atctgaagat gattattgtg aaattttagt atgcactttg tgtaggaaaa   1560

aatggaatgg tcttttaaac agcttttggg gggtactttg gaagtgtcta ataaggtgtc   1620

acaatttttg gtagtaggta tttcgtgaga agttcaacac caaaactgga acatagttct   1680

ccttcaagtg ttggcgacag cggggcttcc tgattctgga atataacttt gtgtaaatta   1740

acagccacct atagaagagt ccatctgctg tgaaggagag acagagaact ctgggttccg   1800

tcgtcctgtc cacgtgctgt accaagtgct ggtgccagcc tgttacctgt tctcactgaa   1860

aagtctggct aatgctcttg tgtagtcact tctgattctg acaatcaatc aatcaatggc   1920

ctagagcact gactgttaac acaaacgtca ctagcaaagt agcaacagct ttaagtctaa   1980

atacaaagct gttctgtgtg agaatttttt aaaaggctac ttgtataata acccttgtca   2040

tttttaatgt acaaaacgct attaagtggc ttagaatttg aacatttgtg gtctttattt   2100

actttgcttc gtgtgtgggc aaagcaacat cttccctaaa tatatattac caagaaaagc   2160

aagaagcaga ttaggttttt gacaaaacaa acaggccaaa agggggctga cctggagcag   2220

agcatggtga gaggcaaggc atgagagggc aagtttgttg tggacagatc tgtgcctact   2280

ttattactgg agtaaaagaa aacaaagttc attgatgtcg aaggatatat acagtgttag   2340

aaattaggac tgtttagaaa aacaggaata caatggttgt ttttatcata gtgtacacat   2400

ttagcttgtg gtaaatgact cacaaaactg attttaaaat caagttaatg tgaattttga   2460

aaattactac ttaatcctaa ttcacaataa caatggcatt aaggtttgac ttgagttggt   2520

tcttagtatt atttatggta aataggctct taccacttgc aaataactgg ccacatcatt   2580

aatgactgac ttcccagtaa ggctctctaa ggggtaagta ggaggatcca caggatttga   2640

gatgctaagg ccccagagat cgtttgatcc aaccctctta ttttcagagg ggaaaatggg   2700

gcctagaagt tacagagcat ctagctggtg cgctggcacc cctggcctca cacagactcc   2760

cgagtagctg ggactacagg cacacagtca ctgaagcagg ccctgtttgc aattcacgtt   2820

gccacctcca acttaaacat tcttcatatg tgatgtcctt agtcactaag gttaaacttt   2880

cccacccaga aaaggcaact tagataaaat cttagagtac tttcatactc ttctaagtcc   2940

tcttccagcc tcactttgag tcctccttgg ggttgatagg aattttctct tgctttctca   3000

ataaagtctc tattcatctc atgtttaatt tgtacgcata gaattgctga gaaataaaat   3060

gttctgttca acttataaaa cttgtcacag ctctgttttt ttgcttttcc ccttcatcct   3120

ctattagatc cttaaagaat ccaccctcaa actgtggact aaggatggca gtttgcctta   3180

aaccttctgt ggaatgag                                                 3198


<210>  6109
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6109

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6110
<211>  3198
<212>  DNA
<213>  Homo sapiens

<400>  6110
gtttcaaatg cagctgcccg ggctataaga tcacacccga aggcgtccgg gaatcttcac     60

tttttccgtt gctagcagtg gaagggtcac agaccaaaca ctaaggcctg agcggtgaca    120

accgaggcga gatgatggtc aacagggaat gcctcgtggg agaaaaaaga caattttatt    180

ctcagcgctg attttgagat gatgggcttg ggaaacgggc gtcgcagcat gaagtcgccg    240

cccctcgtgc tggccgccct ggtggcctgc atcatcgtct tgggcttcaa ctactggatt    300

gcgagctccc ggagcgtgga cctccagaca cggatcatgg agctggaagg cagggtccgc    360

agggcggctg cagagagagg cgccgtggag ctgaagaaga acgagttcca gggagagctg    420

gagaagcagc gggagcagct tgacaaaatc cagtccagcc acaacttcca gctggagagc    480

gtcaacaagc tgtaccagga cgaaaaggcg gttttggtga ataacatcac cacaggtgag    540

aggctcatcc gagtgctgca agaccagtta aagaccctgc agaggaatta cggcaggctg    600

cagcaggatg tcctccagtt tcagaagaac cagaccaacc tggagaggaa gttctcctac    660

gacctgagcc agtgcatcaa tcagatgaag gaggtgaagg aacagtgtga ggagcgaata    720

gaagaggtca ccaaaaaggg gaatgaagct gtagcttcca gagacctgag tgaaaacaac    780

gaccagagac agcagctcca agccctcagt gagcctcagc ccaggctgca ggcagcaggc    840

ctgccacaca cagaggtgcc acaagggaag ggaaacgtgc ttggtaacag caagtcccag    900

acaccagccc ccagttccga agtggttttg gattcaaaga gacaagttga gaaagaggaa    960

accaatgaga tccaggtggt gaatgaggag cctcagaggg acaggctgcc gcaggagcca   1020

ggccgggagc aggtggtgga agacagacct gtaggtggaa gaggcttcgg gggagccgga   1080

gaactgggcc agaccccaca ggtgcaggct gccctgtcag tgagccagga aaatccagag   1140

atggagggcc ctgagcgaga ccagcttgtc atccccgacg gacaggagga ggagcaggaa   1200

gctgccgggg aagggagaaa ccagcagaaa ctgagaggag aagatgacta caacatggat   1260

gaaaatgaag cagaatctga gacagacaag caagcagccc tggcagggaa tgacagaaac   1320

atagatgttt ttaatgttga agatcagaaa agagacacca taaatttact tgatcagcgt   1380

gaaaagcgga atcatacact ctgaattgaa ctggaatcac atatttcaca acagggccga   1440

agagatgact ataaaatgtt catgagggac tgaatactga aaactgtgaa atgtactaaa   1500

taaaatgtac atctgaagat gattattgtg aaattttagt atgcactttg tgtaggaaaa   1560

aatggaatgg tcttttaaac agcttttggg gggtactttg gaagtgtcta ataaggtgtc   1620

acaatttttg gtagtaggta tttcgtgaga agttcaacac caaaactgga acatagttct   1680

ccttcaagtg ttggcgacag cggggcttcc tgattctgga atataacttt gtgtaaatta   1740

acagccacct atagaagagt ccatctgctg tgaaggagag acagagaact ctgggttccg   1800

tcgtcctgtc cacgtgctgt accaagtgct ggtgccagcc tgttacctgt tctcactgaa   1860

aagtctggct aatgctcttg tgtagtcact tctgattctg acaatcaatc aatcaatggc   1920

ctagagcact gactgttaac acaaacgtca ctagcaaagt agcaacagct ttaagtctaa   1980

atacaaagct gttctgtgtg agaatttttt aaaaggctac ttgtataata acccttgtca   2040

tttttaatgt acaaaacgct attaagtggc ttagaatttg aacatttgtg gtctttattt   2100

actttgcttc gtgtgtgggc aaagcaacat cttccctaaa tatatattac caagaaaagc   2160

aagaagcaga ttaggttttt gacaaaacaa acaggccaaa agggggctga cctggagcag   2220

agcatggtga gaggcaaggc atgagagggc aagtttgttg tggacagatc tgtgcctact   2280

ttattactgg agtaaaagaa aacaaagttc attgatgtcg aaggatatat acagtgttag   2340

aaattaggac tgtttagaaa aacaggaata caatggttgt ttttatcata gtgtacacat   2400

ttagcttgtg gtaaatgact cacaaaactg attttaaaat caagttaatg tgaattttga   2460

aaattactac ttaatcctaa ttcacaataa caatggcatt aaggtttgac ttgagttggt   2520

tcttagtatt atttatggta aataggctct taccacttgc aaataactgg ccacatcatt   2580

aatgactgac ttcccagtaa ggctctctaa ggggtaagta ggaggatcca caggatttga   2640

gatgctaagg ccccagagat cgtttgatcc aaccctctta ttttcagagg ggaaaatggg   2700

gcctagaagt tacagagcat ctagctggtg cgctggcacc cctggcctca cacagactcc   2760

cgagtagctg ggactacagg cacacagtca ctgaagcagg ccctgtttgc aattcacgtt   2820

gccacctcca acttaaacat tcttcatatg tgatgtcctt agtcactaag gttaaacttt   2880

cccacccaga aaaggcaact tagataaaat cttagagtac tttcatactc ttctaagtcc   2940

tcttccagcc tcactttgag tcctccttgg ggttgatagg aattttctct tgctttctca   3000

ataaagtctc tattcatctc atgtttaatt tgtacgcata gaattgctga gaaataaaat   3060

gttctgttca acttataaaa cttgtcacag ctctgttttt ttgcttttcc ccttcatcct   3120

ctattagatc cttaaagaat ccaccctcaa actgtggact aaggatggca gtttgcctta   3180

aaccttctgt ggaatgag                                                 3198


<210>  6111
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6111

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6112
<211>  3076
<212>  DNA
<213>  Homo sapiens

<400>  6112
gggggcgggg ccttgccgct gcggaggccg gagacgcggc ggcgctggac gcggaggcgc     60

tgggcgcacg gcgcggagcc ggccggagct cgaggccggc ggcggcggga gagcgacccg    120

ggcggcctcg tagcggggcc ccggatcccc gagtggcggc cggagcctcg aaaagagatt    180

ctcagcgctg attttgagat gatgggcttg ggaaacgggc gtcgcagcat gaagtcgccg    240

cccctcgtgc tggccgccct ggtggcctgc atcatcgtct tgggcttcaa ctactggatt    300

gcgagctccc ggagcgtgga cctccagaca cggatcatgg agctggaagg cagggtccgc    360

agggcggctg cagagagagg cgccgtggag ctgaagaaga acgagttcca gggagagctg    420

gagaagcagc gggagcagct tgacaaaatc cagtccagcc acaacttcca gctggagagc    480

gtcaacaagc tgtaccagga cgaaaaggcg gttttggtga ataacatcac cacaggtgag    540

aggctcatcc gagtgctgca agaccagtta aagaccctgc agaggaatta cggcaggctg    600

cagcaggatg tcctccagtt tcagaagaac cagaccaacc tggagaggaa gttctcctac    660

gacctgagcc agtgcatcaa tcagatgaag gaggtgaagg aacagtgtga ggagcgaata    720

gaagaggtca ccaaaaaggg gaatgaagct gtagcttcca gagacctgag tgaaaacaac    780

gaccagagac agcagctcca agccctcagt gagcctcagc ccaggctgca ggcagcaggc    840

ctgccacaca cagaggtgcc acaagggaag ggaaacgtgc ttggtaacag caagtcccag    900

acaccagccc ccagttccga agtggttttg gattcaaaga gacaagttga gaaagaggaa    960

accaatgaga tccaggtggt gaatgaggag cctcagaggg acaggctgcc gcaggagcca   1020

ggccgggagc aggtggtgga agacagacct gtaggtggaa gaggcttcgg gggagccgga   1080

gaactgggcc agaccccaca ggtgcaggct gccctgtcag tgagccagga aaatccagag   1140

atggagggcc ctgagcgaga ccagcttgtc atccccgacg gacaggagga ggagcaggaa   1200

gctgccgggg aagggagaaa ccagcagaaa ctgagaggag aagatgacta caacatggat   1260

gaaaatgaag cagaatctga gacagacaag caagcagccc tggcagggaa tgacagaaac   1320

atagatgttt ttaatgttga agatcagaaa agagacacca taaatttact tgatcagcgt   1380

gaaaagcgga atcatacact ctgaattgaa ctggaatcac atatttcaca acagggccga   1440

agagatgact ataaaatgtt catgagggac tgaatactga aaactgtgaa atgtactaaa   1500

taaaatgtac atctgaagat gattattgtg aaattttagt atgcactttg tgtaggaaaa   1560

aatggaatgg tcttttaaac agcttttggg gggtactttg gaagtgtcta ataaggtgtc   1620

acaatttttg gtagtaggta tttcgtgaga agttcaacac caaaactgga acatagttct   1680

ccttcaagtg ttggcgacag cggggcttcc tgattctgga atataacttt gtgtaaatta   1740

acagccacct atagaagagt ccatctgctg tgaaggagag acagagaact ctgggttccg   1800

tcgtcctgtc cacgtgctgt accaagtgct ggtgccagcc tgttacctgt tctcactgaa   1860

aagtctggct aatgctcttg tgtagtcact tctgattctg acaatcaatc aatcaatggc   1920

ctagagcact gactgttaac acaaacgtca ctagcaaagt agcaacagct ttaagtctaa   1980

atacaaagct gttctgtgtg agaatttttt aaaaggctac ttgtataata acccttgtca   2040

tttttaatgt acaaaacgct attaagtggc ttagaatttg aacatttgtg gtctttattt   2100

actttgcttc gtgtgtgggc aaagcaacat cttccctaaa tatatattac caagaaaagc   2160

aagaagcaga ttaggttttt gacaaaacaa acaggccaaa agggggctga cctggagcag   2220

agcatggtga gaggcaaggc atgagagggc aagtttgttg tggacagatc tgtgcctact   2280

ttattactgg agtaaaagaa aacaaagttc attgatgtcg aaggatatat acagtgttag   2340

aaattaggac tgtttagaaa aacaggaata caatggttgt ttttatcata gtgtacacat   2400

ttagcttgtg gtaaatgact cacaaaactg attttaaaat caagttaatg tgaattttga   2460

aaattactac ttaatcctaa ttcacaataa caatggcatt aaggtttgac ttgagttggt   2520

tcttagtatt atttatggta aataggctct taccacttgc aaataactgg ccacatcatt   2580

aatgactgac ttcccagtaa ggctctctaa ggggtaagta ggaggatcca caggatttga   2640

gatgctaagg ccccagagat cgtttgatcc aaccctctta ttttcagagg ggaaaatggg   2700

gcctagaagt tacagagcat ctagctggtg cgctggcacc cctggcctca cacagactcc   2760

cgagtagctg ggactacagg cacacagtca ctgaagcagg ccctgtttgc aattcacgtt   2820

gccacctcca acttaaacat tcttcatatg tgatgtcctt agtcactaag gttaaacttt   2880

cccacccaga aaaggcaact tagataaaat cttagagtac tttcatactc ttctaagtcc   2940

tcttccagcc tcactttgag tcctccttgg ggttgatagg aattttctct tgctttctca   3000

ataaagtctc tattcatctc atgtttaatt tgtacgcata gaattgctga gaaataaaat   3060

gttctgttca acttat                                                   3076


<210>  6113
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6113

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6114
<211>  3076
<212>  DNA
<213>  Homo sapiens

<400>  6114
gtttcaaatg cagctgcccg ggctataaga tcacacccga aggcgtccgg gaatcttcac     60

tttttccgtt gctagcagtg gaagggtcac agaccaaaca ctaaggcctg agcggtgaca    120

accgaggcga gatgatggtc aacagggaat gcctcgtggg agaaaaaaga caattttatt    180

ctcagcgctg attttgagat gatgggcttg ggaaacgggc gtcgcagcat gaagtcgccg    240

cccctcgtgc tggccgccct ggtggcctgc atcatcgtct tgggcttcaa ctactggatt    300

gcgagctccc ggagcgtgga cctccagaca cggatcatgg agctggaagg cagggtccgc    360

agggcggctg cagagagagg cgccgtggag ctgaagaaga acgagttcca gggagagctg    420

gagaagcagc gggagcagct tgacaaaatc cagtccagcc acaacttcca gctggagagc    480

gtcaacaagc tgtaccagga cgaaaaggcg gttttggtga ataacatcac cacaggtgag    540

aggctcatcc gagtgctgca agaccagtta aagaccctgc agaggaatta cggcaggctg    600

cagcaggatg tcctccagtt tcagaagaac cagaccaacc tggagaggaa gttctcctac    660

gacctgagcc agtgcatcaa tcagatgaag gaggtgaagg aacagtgtga ggagcgaata    720

gaagaggtca ccaaaaaggg gaatgaagct gtagcttcca gagacctgag tgaaaacaac    780

gaccagagac agcagctcca agccctcagt gagcctcagc ccaggctgca ggcagcaggc    840

ctgccacaca cagaggtgcc acaagggaag ggaaacgtgc ttggtaacag caagtcccag    900

acaccagccc ccagttccga agtggttttg gattcaaaga gacaagttga gaaagaggaa    960

accaatgaga tccaggtggt gaatgaggag cctcagaggg acaggctgcc gcaggagcca   1020

ggccgggagc aggtggtgga agacagacct gtaggtggaa gaggcttcgg gggagccgga   1080

gaactgggcc agaccccaca ggtgcaggct gccctgtcag tgagccagga aaatccagag   1140

atggagggcc ctgagcgaga ccagcttgtc atccccgacg gacaggagga ggagcaggaa   1200

gctgccgggg aagggagaaa ccagcagaaa ctgagaggag aagatgacta caacatggat   1260

gaaaatgaag cagaatctga gacagacaag caagcagccc tggcagggaa tgacagaaac   1320

atagatgttt ttaatgttga agatcagaaa agagacacca taaatttact tgatcagcgt   1380

gaaaagcgga atcatacact ctgaattgaa ctggaatcac atatttcaca acagggccga   1440

agagatgact ataaaatgtt catgagggac tgaatactga aaactgtgaa atgtactaaa   1500

taaaatgtac atctgaagat gattattgtg aaattttagt atgcactttg tgtaggaaaa   1560

aatggaatgg tcttttaaac agcttttggg gggtactttg gaagtgtcta ataaggtgtc   1620

acaatttttg gtagtaggta tttcgtgaga agttcaacac caaaactgga acatagttct   1680

ccttcaagtg ttggcgacag cggggcttcc tgattctgga atataacttt gtgtaaatta   1740

acagccacct atagaagagt ccatctgctg tgaaggagag acagagaact ctgggttccg   1800

tcgtcctgtc cacgtgctgt accaagtgct ggtgccagcc tgttacctgt tctcactgaa   1860

aagtctggct aatgctcttg tgtagtcact tctgattctg acaatcaatc aatcaatggc   1920

ctagagcact gactgttaac acaaacgtca ctagcaaagt agcaacagct ttaagtctaa   1980

atacaaagct gttctgtgtg agaatttttt aaaaggctac ttgtataata acccttgtca   2040

tttttaatgt acaaaacgct attaagtggc ttagaatttg aacatttgtg gtctttattt   2100

actttgcttc gtgtgtgggc aaagcaacat cttccctaaa tatatattac caagaaaagc   2160

aagaagcaga ttaggttttt gacaaaacaa acaggccaaa agggggctga cctggagcag   2220

agcatggtga gaggcaaggc atgagagggc aagtttgttg tggacagatc tgtgcctact   2280

ttattactgg agtaaaagaa aacaaagttc attgatgtcg aaggatatat acagtgttag   2340

aaattaggac tgtttagaaa aacaggaata caatggttgt ttttatcata gtgtacacat   2400

ttagcttgtg gtaaatgact cacaaaactg attttaaaat caagttaatg tgaattttga   2460

aaattactac ttaatcctaa ttcacaataa caatggcatt aaggtttgac ttgagttggt   2520

tcttagtatt atttatggta aataggctct taccacttgc aaataactgg ccacatcatt   2580

aatgactgac ttcccagtaa ggctctctaa ggggtaagta ggaggatcca caggatttga   2640

gatgctaagg ccccagagat cgtttgatcc aaccctctta ttttcagagg ggaaaatggg   2700

gcctagaagt tacagagcat ctagctggtg cgctggcacc cctggcctca cacagactcc   2760

cgagtagctg ggactacagg cacacagtca ctgaagcagg ccctgtttgc aattcacgtt   2820

gccacctcca acttaaacat tcttcatatg tgatgtcctt agtcactaag gttaaacttt   2880

cccacccaga aaaggcaact tagataaaat cttagagtac tttcatactc ttctaagtcc   2940

tcttccagcc tcactttgag tcctccttgg ggttgatagg aattttctct tgctttctca   3000

ataaagtctc tattcatctc atgtttaatt tgtacgcata gaattgctga gaaataaaat   3060

gttctgttca acttat                                                   3076


<210>  6115
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6115

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6116
<211>  2065
<212>  DNA
<213>  Homo sapiens

<400>  6116
ccgctgcgga ggccggagac gcggcggcgc tggacgcgga ggcgctgggc gcacggcgcg     60

gagccggccg gagctcgagg ccggcggcgg cgggagagcg acccgggcgg cctcgtagcg    120

gggccccgga tccccgagtg gcggccggag cctcgaaaag agattctcag cgctgatttt    180

gagatgatgg gcttgggaaa cgggcgtcgc agcatgaagt cgccgcccct cgtgctggcc    240

gccctggtgg cctgcatcat cgtcttgggc ttcaactact ggattgcgag ctcccggagc    300

gtggacctcc agacacggat catggagctg gaaggcaggg tccgcagggc ggctgcagag    360

agaggcgccg tggagctgaa gaagaacgag ttccagggag agctggagaa gcagcgggag    420

cagcttgaca aaatccagtc cagccacaac ttccagctgg agagcgtcaa caagctgtac    480

caggacgaaa aggcggtttt ggtgaataac atcaccacag gtgagaggct catccgagtg    540

ctgcaagacc agttaaagac cctgcagagg aattacggca ggctgcagca ggatgtcctc    600

cagtttcaga agaaccagac caacctggag aggaagttct cctacgacct gagccagtgc    660

atcaatcaga tgaaggaggt gaaggaacag tgtgaggagc gaatagaaga ggtcaccaaa    720

aaggggaatg aagctgtagc ttccagagac ctgagtgaaa acaacgacca gagacagcag    780

ctccaagccc tcagtgagcc tcagcccagg ctgcaggcag caggcctgcc acacacagag    840

gtgccacaag ggaagggaaa cgtgcttggt aacagcaagt cccagacacc agcccccagt    900

tccgaagtgg ttttggattc aaagagacaa gttgagaaag aggaaaccaa tgagatccag    960

gtggtgaatg aggagcctca gagggacagg ctgccgcagg agccaggccg ggagcaggtg   1020

gtggaagaca gacctgtagg tggaagaggc ttcgggggag ccggagaact gggccagacc   1080

ccacaggtgc aggctgccct gtcagtgagc caggaaaatc cagagatgga gggccctgag   1140

cgagaccagc ttgtcatccc cgacggacag gaggaggagc aggaagctgc cggggaaggg   1200

agaaaccagc agaaactgag aggagaagat gactacaaca tggatgaaaa tgaagcagaa   1260

tctgagacag acaagcaagc agccctggca gggaatgaca gaaacataga tgtttttaat   1320

gttgaagatc agaaaagaga caccataaat ttacttgatc agcgtgaaaa gcggaatcat   1380

acactctgaa ttgaactgga atcacatatt tcacaacagg gccgaagaga tgactataaa   1440

atgttcatga gggactgaat actgaaaact gtgaaatgta ctaaataaaa tgtacatctg   1500

aagatgatta ttgtgaaatt ttagtatgca ctttgtgtag gaaaaaatgg aatggtcttt   1560

taaacagctt ttggggggta ctttggaagt gtctaataag gtgtcacaat ttttggtagt   1620

aggtatttcg tgagaagttc aacaccaaaa ctggaacata gttctccttc aagtgttggc   1680

gacagcgggg cttcctgatt ctggaatata actttgtgta aattaacagc cacctataga   1740

agagtccatc tgctgtgaag gagagacaga gaactctggg ttccgtcgtc ctgtccacgt   1800

gctgtaccaa gtgctggtgc cagcctgtta cctgttctca ctgaaaagtc tggctaatgc   1860

tcttgtgtag tcacttctga ttctgacaat caatcaatca atggcctaga gcactgactg   1920

ttaacacaaa cgtcactagc aaagtagcaa cagctttaag tctaaataca aagctgttct   1980

gtgtgagaat tttttaaaag gctacttgta taataaccct tgtcattttt aatgtacaaa   2040

acgctattaa gtggcttaga atttg                                         2065


<210>  6117
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6117

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6118
<211>  1509
<212>  DNA
<213>  Homo sapiens

<400>  6118
ccgctgcgga ggccggagac gcggcggcgc tggacgcgga ggcgctgggc gcacggcgcg     60

gagccggccg gagctcgagg ccggcggcgg cgggagagcg acccgggcgg cctcgtagcg    120

gggccccgga tccccgagtg gcggccggag cctcgaaaag agattctcag cgctgatttt    180

gagatgatgg gcttgggaaa cgggcgtcgc agcatgaagt cgccgcccct cgtgctggcc    240

gccctggtgg cctgcatcat cgtcttgggc ttcaactact ggattgcgag ctcccggagc    300

gtggacctcc agacacggat catggagctg gaaggcaggg tccgcagggc ggctgcagag    360

agaggcgccg tggagctgaa gaagaacgag ttccagggag agctggagaa gcagcgggag    420

cagcttgaca aaatccagtc cagccacaac ttccagctgg agagcgtcaa caagctgtac    480

caggacgaaa aggcggtttt ggtgaataac atcaccacag gtgagaggct catccgagtg    540

ctgcaagacc agttaaagac cctgcagagg aattacggca ggctgcagca ggatgtcctc    600

cagtttcaga agaaccagac caacctggag aggaagttct cctacgacct gagccagtgc    660

atcaatcaga tgaaggaggt gaaggaacag tgtgaggagc gaatagaaga ggtcaccaaa    720

aaggggaatg aagctgtagc ttccagagac ctgagtgaaa acaacgacca gagacagcag    780

ctccaagccc tcagtgagcc tcagcccagg ctgcaggcag caggcctgcc acacacagag    840

gtgccacaag ggaagggaaa cgtgcttggt aacagcaagt cccagacacc agcccccagt    900

tccgaagtgg ttttggattc aaagagacaa gttgagaaag aggaaaccaa tgagatccag    960

gtggtgaatg aggagcctca gagggacagg ctgccgcagg agccaggccg ggagcaggtg   1020

gtggaagaca gacctgtagg tggaagaggc ttcgggggag ccggagaact gggccagacc   1080

ccacaggtgc aggctgccct gtcagtgagc caggaaaatc cagagatgga gggccctgag   1140

cgagaccagc ttgtcatccc cgacggacag gaggaggagc aggaagctgc cggggaaggg   1200

agaaaccagc agaaactgag aggagaagat gactacaaca tggatgaaaa tgaagcagaa   1260

tctgagacag acaagcaagc agccctggca gggaatgaca gaaacataga tgtttttaat   1320

gttgaagatc agaaaagaga caccataaat ttacttgatc agcgtgaaaa gcggaatcat   1380

acactctgaa ttgaactgga atcacatatt tcacaacagg gccgaagaga tgactataaa   1440

atgttcatga gggactgaat actgaaaact gtgaaatgta ctaaataaaa tgtacatctg   1500

aagatgatt                                                           1509


<210>  6119
<211>  401
<212>  PRT
<213>  Homo sapiens

<400>  6119

Met Met Gly Leu Gly Asn Gly Arg Arg Ser Met Lys Ser Pro Pro Leu 
1               5                   10                  15


Val Leu Ala Ala Leu Val Ala Cys Ile Ile Val Leu Gly Phe Asn Tyr 
            20                  25                  30


Trp Ile Ala Ser Ser Arg Ser Val Asp Leu Gln Thr Arg Ile Met Glu 
        35                  40                  45


Leu Glu Gly Arg Val Arg Arg Ala Ala Ala Glu Arg Gly Ala Val Glu 
    50                  55                  60


Leu Lys Lys Asn Glu Phe Gln Gly Glu Leu Glu Lys Gln Arg Glu Gln 
65                  70                  75                  80


Leu Asp Lys Ile Gln Ser Ser His Asn Phe Gln Leu Glu Ser Val Asn 
                85                  90                  95


Lys Leu Tyr Gln Asp Glu Lys Ala Val Leu Val Asn Asn Ile Thr Thr 
            100                 105                 110


Gly Glu Arg Leu Ile Arg Val Leu Gln Asp Gln Leu Lys Thr Leu Gln 
        115                 120                 125


Arg Asn Tyr Gly Arg Leu Gln Gln Asp Val Leu Gln Phe Gln Lys Asn 
    130                 135                 140


Gln Thr Asn Leu Glu Arg Lys Phe Ser Tyr Asp Leu Ser Gln Cys Ile 
145                 150                 155                 160


Asn Gln Met Lys Glu Val Lys Glu Gln Cys Glu Glu Arg Ile Glu Glu 
                165                 170                 175


Val Thr Lys Lys Gly Asn Glu Ala Val Ala Ser Arg Asp Leu Ser Glu 
            180                 185                 190


Asn Asn Asp Gln Arg Gln Gln Leu Gln Ala Leu Ser Glu Pro Gln Pro 
        195                 200                 205


Arg Leu Gln Ala Ala Gly Leu Pro His Thr Glu Val Pro Gln Gly Lys 
    210                 215                 220


Gly Asn Val Leu Gly Asn Ser Lys Ser Gln Thr Pro Ala Pro Ser Ser 
225                 230                 235                 240


Glu Val Val Leu Asp Ser Lys Arg Gln Val Glu Lys Glu Glu Thr Asn 
                245                 250                 255


Glu Ile Gln Val Val Asn Glu Glu Pro Gln Arg Asp Arg Leu Pro Gln 
            260                 265                 270


Glu Pro Gly Arg Glu Gln Val Val Glu Asp Arg Pro Val Gly Gly Arg 
        275                 280                 285


Gly Phe Gly Gly Ala Gly Glu Leu Gly Gln Thr Pro Gln Val Gln Ala 
    290                 295                 300


Ala Leu Ser Val Ser Gln Glu Asn Pro Glu Met Glu Gly Pro Glu Arg 
305                 310                 315                 320


Asp Gln Leu Val Ile Pro Asp Gly Gln Glu Glu Glu Gln Glu Ala Ala 
                325                 330                 335


Gly Glu Gly Arg Asn Gln Gln Lys Leu Arg Gly Glu Asp Asp Tyr Asn 
            340                 345                 350


Met Asp Glu Asn Glu Ala Glu Ser Glu Thr Asp Lys Gln Ala Ala Leu 
        355                 360                 365


Ala Gly Asn Asp Arg Asn Ile Asp Val Phe Asn Val Glu Asp Gln Lys 
    370                 375                 380


Arg Asp Thr Ile Asn Leu Leu Asp Gln Arg Glu Lys Arg Asn His Thr 
385                 390                 395                 400


Leu 



<210>  6120
<211>  2771
<212>  DNA
<213>  Homo sapiens

<400>  6120
agacaaaacg atcgcggtta aagcttgcgg ctcagagccc acctggccgc gctgctggga     60

aacggacgga gcggcgcttc aatcagaggt attactcagc acagaaattc aggagacaca    120

gacaagttct tccacgatgt cgtacagacg agaactagag aaataccgtg acctggatga    180

agatgaaatc cttggagccc taacagagga agagctgagg accctggaaa atgagctgga    240

tgagctggac cctgataatg cactgctgcc tgcaggcctg aggcagaagg atcagaccac    300

caaggcgccc acgggcccct ttaaaagaga ggagctcttg gatcacttgg aaaagcaagc    360

aaaggagttt aaggaccgag aagatctggt cccctacaca ggggaaaaac gaggaaaggt    420

ctgggttcct aagcagaagc cactggatcc tgtgctggaa agtgtgacgc tggaaccgga    480

gctggaggaa gccttggcaa atgcttcaga tgcagaactc tgtgacattg cagcgatcct    540

gggcatgcac acgctcatga gtaaccagca gtactaccag gccctgagca gcagctccat    600

catgaacaag gaggggctca acagcgtgat taaacccaca caatacaagc ctgtgcccga    660

cgaagaacca aattcaacag acgtagagga aacgctggaa cggataaaga acaacgaccc    720

aaaacttgaa gaagttaacc tcaataatat ccggaatatc cccatcccca ccctcaaggc    780

atatgcagaa gccctgaaag aaaactcata tgtgaagaag ttcagcatcg tggggacacg    840

gagtaatgac cccgtggcgt atgcccttgc tgagatgctc aaggagaaca aggtgttgaa    900

gacactgaat gtggaatcca acttcatttc tggagctggg attctgcgcc tggtagaagc    960

cctcccatac aacacttctc tggtggaaat gaaaattgac aaccagagcc agcccctggg   1020

caacaaagtg gaaatggaga ttgtgagcat gttggaaaaa aacgcaacac ttctcaaatt   1080

cggctaccac tttacccagc aaggaccccg gcttcgggca tccaacgcaa tgatgaacaa   1140

caatgacctt gtgaggaaga ggaggcttgc ggacctgact gggcccatca ttcccaagtg   1200

ccggagtggt gtctagtgtg tggcggtgga gtccatgcct ttgaactgga tgtgttctat   1260

tgatgacctg tgctctgcag gggaaaccag aaggcaaaat gctggcagca tgaaaccctt   1320

ttgtggttca gttctttatg cactaaggtt ttaggttgac tagtggttgt agttgaaaat   1380

tttataaaat accgttaatg tgaagttttt ctttagtcac agaagttgaa tctggttatt   1440

atttaaaaac tagaagcccc caaaccagca gatcttactg aagatgatgt tccagcagca   1500

gcgacttagc cccaggagcc cagtttcaat ggccttgctg tgtggtgttt caagtgcatt   1560

taaaatgtgt gacacagaaa cggcacactc ttccacatgc ttttgaagta ttataaaaca   1620

ctttattaca aatttgtctt agctattagc aaataaaact gattatcatt ctttattaac   1680

cctccttgga attttgaaaa cctcgattaa agttgccaaa ttgattactg gatccagaac   1740

acaattttcc cctcagaaca gatagacaga ctgaagccac tgaactctgc caggagtcaa   1800

catgagattc cttttgctgg atatgcagaa atgataggaa aaaaaccaat ggtgaaattt   1860

caagtttcaa aaaccaacct ttcattacca atcccaggca acaaacatgt ccctgagtgt   1920

tctttaagaa catttgggat ttatgtacaa tttaatactg gagttagaac tttttcctta   1980

ttgaatgcca accttatgat ggatgtgaaa atctacggcc aaatactttt gaaaacacct   2040

ttctatattg cacagtgggc aaatggctta tgtgaggtaa gacactagag ggataaattt   2100

ccagatcaac atggctatgg tatttagtaa tggcccagct tagagacttc agctactgat   2160

ctcatcactt attagacaaa ttgctgctga ccttacgcct gtatattaag cctccgcagg   2220

atgccggaca atggtgaaga aactccagat atcaaggaat tgggaaatcc tggccaaacc   2280

accccaagat gattacactg aaatgtagta ttagtactgc tgccagatct ctttttaaca   2340

tcatgtgcgt ctcttgggat ccagcaaaag tgttaagcca caatgccctt gtgcctttta   2400

atataccaca gtgccagtta aactaatatt tttgtttgtt gcttttggga gttattttca   2460

ttagtgattt cagcaaatct catgataaag gacaaggtca agaactccag agcactgagc   2520

agagaggctg gtgatgaaaa ggtgaaggcc tgcgcactga actgtaaggc agtgggcagt   2580

acagggtaac tggaggcggg gccagggcct cagcgctatg gaagagtgtc cactgaggct   2640

gcacatggcc caggagtggc accatgttgc agggacaacc atccccattt ggcttctcct   2700

taaaacacaa ttgcagctgc attctgcatc gctgaaaact gcaatataat attaaatctg   2760

ttggtctatg c                                                        2771


<210>  6121
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6121

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6122
<211>  3265
<212>  DNA
<213>  Homo sapiens

<400>  6122
agacaaaacg atcgcggtta aagcttgcgg ctcagagccc acctggccgc gctgctggga     60

aacggacgga gcggcgcttc aatcagaggt attactcagc acagaaattc aggagacaca    120

gacaagttct tccacgatgt cgtacagacg agaactagag aaataccgtg acctggatga    180

agatgaaatc cttggagccc taacagagga agagctgagg accctggaaa atgagctgga    240

tgagctggac cctgataatg cactgctgcc tgcaggcctg aggcagaagg atcagaccac    300

caaggcgccc acgggcccct ttaaaagaga ggagctcttg gatcacttgg aaaagcaagc    360

aaaggagttt aaggaccgag aagatctggt cccctacaca ggggaaaaac gaggaaaggt    420

ctgggttcct aagcagaagc cactggatcc tgtgctggaa agtgtgacgc tggaaccgga    480

gctggaggaa gccttggcaa atgcttcaga tgcagaactc tgtgacattg cagcgatcct    540

gggcatgcac acgctcatga gtaaccagca gtactaccag gccctgagca gcagctccat    600

catgaacaag gaggggctca acagcgtgat taaacccaca caatacaagc ctgtgcccga    660

cgaagaacca aattcaacag acgtagagga aacgctggaa cggataaaga acaacgaccc    720

aaaacttgaa gaagttaacc tcaataatat ccggaatatc cccatcccca ccctcaaggc    780

atatgcagaa gccctgaaag aaaactcata tgtgaagaag ttcagcatcg tggggacacg    840

gagtaatgac cccgtggcgt atgcccttgc tgagatgctc aaggagaaca aggtgttgaa    900

gacactgaat gtggaatcca acttcatttc tggagctggg attctgcgcc tggtagaagc    960

cctcccatac aacacttctc tggtggaaat gaaaattgac aaccagagcc agcccctggg   1020

caacaaagtg gaaatggaga ttgtgagcat gttggaaaaa aacgcaacac ttctcaaatt   1080

cggctaccac tttacccagc aaggaccccg gcttcgggca tccaacgcaa tgatgaacaa   1140

caatgacctt gtgaggaaga ggaggcttgc ggacctgact gggcccatca ttcccaagtg   1200

ccggagtggt gtctagtgtg tggcggtgga gtccatgcct ttgaactgga tgtgttctat   1260

tgatgacctg tgctctgcag gggaaaccag aaggcaaaat gctggcagca tgaaaccctt   1320

ttgtggttca gttctttatg cactaaggtt ttaggttgac tagtggttgt agttgaaaat   1380

tttataaaat accgttaatg tgaagttttt ctttagtcac agaagttgaa tctggttatt   1440

atttaaaaac tagaagcccc caaaccagca gatcttactg aagatgatgt tccagcagca   1500

gcgacttagc cccaggagcc cagtttcaat ggccttgctg tgtggtgttt caagtgcatt   1560

taaaatgtgt gacacagaaa cggcacactc ttccacatgc ttttgaagta ttataaaaca   1620

ctttattaca aatttgtctt agctattagc aaataaaact gattatcatt ctttattaac   1680

cctccttgga attttgaaaa cctcgattaa agttgccaaa ttgattactg gatccagaac   1740

acaattttcc cctcagaaca gatagacaga ctgaagccac tgaactctgc caggagtcaa   1800

catgagattc cttttgctgg atatgcagaa atgataggaa aaaaaccaat ggtgaaattt   1860

caagtttcaa aaaccaacct ttcattacca atcccaggca acaaacatgt ccctgagtgt   1920

tctttaagaa catttgggat ttatgtacaa tttaatactg gagttagaac tttttcctta   1980

ttgaatgcca accttatgat ggatgtgaaa atctacggcc aaatactttt gaaaacacct   2040

ttctatattg cacagtgggc aaatggctta tgtgaggtaa gacactagag ggataaattt   2100

ccagatcaac atggctatgg tatttagtaa tggcccagct tagagacttc agctactgat   2160

ctcatcactt attagacaaa ttgctgctga ccttacgcct gtatattaag cctccgcagg   2220

atgccggaca atggtgaaga aactccagat atcaaggaat tgggaaatcc tggccaaacc   2280

accccaagat gattacactg aaatgtagta ttagtactgc tgccagatct ctttttaaca   2340

tcatgtgcgt ctcttgggat ccagcaaaag tgttaagcca caatgccctt gtgcctttta   2400

atataccaca gtgccagtta aactaatatt tttgtttgtt gcttttggga gttattttca   2460

ttagtgattt cagcaaatct catgataaag gacaaggtca agaactccag agcactgagc   2520

agagaggctg gtgatgaaaa ggtgaaggcc tgcgcactga actgtaaggc agtgggcagt   2580

acagggtaac tggaggcggg gccagggcct cagcgctatg gaagagtgtc cactgaggct   2640

gcacatggcc caggagtggc accatgttgc agggacaacc atccccattt ggcttctcct   2700

taaaacacaa ttgcagctgc attctgcatc gctgaaaact gcaatataat attaaatctg   2760

ttggtctatg catggctgcg tatgtgtttc ttggaacctg tgtgacaggg acatgtgcct   2820

ggcacactgg ccagaagact gggcagccac catggcagtg ctggatgacc tcagtaagaa   2880

tgtgtcatgt attccaggtg ctgatctaaa aactgtggct caaatgtcac cgagcttata   2940

tgaagctccc agagagaaca tttaaaagct cagagagtaa gtgctgggga aagcagagct   3000

atcagaggaa atctctcata gaaacgaaac caaaccaaca gaaaatgaag aaggccacat   3060

ctttaaggcc acctctgcct ctatcagatg agctgctggt ctagatcagg ggctggcaaa   3120

cttttctgta aaaggccaga cagtaaaaat ttccgatttt gcaggccaca tagtgtctgt   3180

tgcaactatt caactctgcc atagatcatg tgtaaaggaa tgggtgtggc tgttcaataa   3240

actatacagt tgacccttga acaat                                         3265


<210>  6123
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6123

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6124
<211>  3406
<212>  DNA
<213>  Homo sapiens

<400>  6124
agacaaaacg atcgcggtta aagcttgcgg ctcagagccc acctggccgc gctgctggga     60

aacggacgga gcggcgcttc aatcagaggt attactcagc acagaaattc aggagacaca    120

gacaagttct tccacgatgt cgtacagacg agaactagag aaataccgtg acctggatga    180

agatgaaatc cttggagccc taacagagga agagctgagg accctggaaa atgagctgga    240

tgagctggac cctgataatg cactgctgcc tgcaggcctg aggcagaagg atcagaccac    300

caaggcgccc acgggcccct ttaaaagaga ggagctcttg gatcacttgg aaaagcaagc    360

aaaggagttt aaggaccgag aagatctggt cccctacaca ggggaaaaac gaggaaaggt    420

ctgggttcct aagcagaagc cactggatcc tgtgctggaa agtgtgacgc tggaaccgga    480

gctggaggaa gccttggcaa atgcttcaga tgcagaactc tgtgacattg cagcgatcct    540

gggcatgcac acgctcatga gtaaccagca gtactaccag gccctgagca gcagctccat    600

catgaacaag gaggggctca acagcgtgat taaacccaca caatacaagc ctgtgcccga    660

cgaagaacca aattcaacag acgtagagga aacgctggaa cggataaaga acaacgaccc    720

aaaacttgaa gaagttaacc tcaataatat ccggaatatc cccatcccca ccctcaaggc    780

atatgcagaa gccctgaaag aaaactcata tgtgaagaag ttcagcatcg tggggacacg    840

gagtaatgac cccgtggcgt atgcccttgc tgagatgctc aaggagaaca aggtgttgaa    900

gacactgaat gtggaatcca acttcatttc tggagctggg attctgcgcc tggtagaagc    960

cctcccatac aacacttctc tggtggaaat gaaaattgac aaccagagcc agcccctggg   1020

caacaaagtg gaaatggaga ttgtgagcat gttggaaaaa aacgcaacac ttctcaaatt   1080

cggctaccac tttacccagc aaggaccccg gcttcgggca tccaacgcaa tgatgaacaa   1140

caatgacctt gtgaggaaga ggaggcttgc ggacctgact gggcccatca ttcccaagtg   1200

ccggagtggt gtctagtgtg tggcggtgga gtccatgcct ttgaactgga tgtgttctat   1260

tgatgacctg tgctctgcag gggaaaccag aaggcaaaat gctggcagca tgaaaccctt   1320

ttgtggttca gttctttatg cactaaggtt ttaggttgac tagtggttgt agttgaaaat   1380

tttataaaat accgttaatg tgaagttttt ctttagtcac agaagttgaa tctggttatt   1440

atttaaaaac tagaagcccc caaaccagca gatcttactg aagatgatgt tccagcagca   1500

gcgacttagc cccaggagcc cagtttcaat ggccttgctg tgtggtgttt caagtgcatt   1560

taaaatgtgt gacacagaaa cggcacactc ttccacatgc ttttgaagta ttataaaaca   1620

ctttattaca aatttgtctt agctattagc aaataaaact gattatcatt ctttattaac   1680

cctccttgga attttgaaaa cctcgattaa agttgccaaa ttgattactg gatccagaac   1740

acaattttcc cctcagaaca gatagacaga ctgaagccac tgaactctgc caggagtcaa   1800

catgagattc cttttgctgg atatgcagaa atgataggaa aaaaaccaat ggtgaaattt   1860

caagtttcaa aaaccaacct ttcattacca atcccaggca acaaacatgt ccctgagtgt   1920

tctttaagaa catttgggat ttatgtacaa tttaatactg gagttagaac tttttcctta   1980

ttgaatgcca accttatgat ggatgtgaaa atctacggcc aaatactttt gaaaacacct   2040

ttctatattg cacagtgggc aaatggctta tgtgaggtaa gacactagag ggataaattt   2100

ccagatcaac atggctatgg tatttagtaa tggcccagct tagagacttc agctactgat   2160

ctcatcactt attagacaaa ttgctgctga ccttacgcct gtatattaag cctccgcagg   2220

atgccggaca atggtgaaga aactccagat atcaaggaat tgggaaatcc tggccaaacc   2280

accccaagat gattacactg aaatgtagta ttagtactgc tgccagatct ctttttaaca   2340

tcatgtgcgt ctcttgggat ccagcaaaag tgttaagcca caatgccctt gtgcctttta   2400

atataccaca gtgccagtta aactaatatt tttgtttgtt gcttttggga gttattttca   2460

ttagtgattt cagcaaatct catgataaag gacaaggtca agaactccag agcactgagc   2520

agagaggctg gtgatgaaaa ggtgaaggcc tgcgcactga actgtaaggc agtgggcagt   2580

acagggtaac tggaggcggg gccagggcct cagcgctatg gaagagtgtc cactgaggct   2640

gcacatggcc caggagtggc accatgttgc agggacaacc atccccattt ggcttctcct   2700

taaaacacaa ttgcagctgc attctgcatc gctgaaaact gcaatataat attaaatctg   2760

ttggtctatg catggctgcg tatgtgtttc ttggaacctg tgtgacaggg acatgtgcct   2820

ggcacactgg ccagaagact gggcagccac catggcagtg ctggatgacc tcagtaagaa   2880

tgtgtcatgt attccaggtg ctgatctaaa aactgtggct caaatgtcac cgagcttata   2940

tgaagctccc agagagaaca tttaaaagct cagagagtaa gtgctgggga aagcagagct   3000

atcagaggaa atctctcata gaaacgaaac caaaccaaca gaaaatgaag aaggccacat   3060

ctttaaggcc acctctgcct ctatcagatg agctgctggt ctagatcagg ggctggcaaa   3120

cttttctgta aaaggccaga cagtaaaaat ttccgatttt gcaggccaca tagtgtctgt   3180

tgcaactatt caactctgcc atagatcatg tgtaaaggaa tgggtgtggc tgttcaataa   3240

actatacagt tgacccttga acaatatggg tttgaactgc atggctgcac ttatatatgg   3300

atttttttca accatacagg ttgaaaatac agtattggca gggggcgaaa cctgcgtaca   3360

tggagggctg atttatcaca tacgtgggtt ctgtagggcc cactgt                  3406


<210>  6125
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6125

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6126
<211>  1754
<212>  DNA
<213>  Homo sapiens

<400>  6126
agctcccgcc cgcccgcggc cgcccgggag ctcgtccagc cccgcgctgc gctcgcccgc     60

ccgctgcccg ccggagcacc gcggcctccg cccgcgtcca tctgcccgcc gcccgcgcct    120

gttccgcagc ccgcgtccgc gccggcccca cagctctgcg tccgggtatt actcagcaca    180

gaaattcagg agacacagac aagttcttcc acgatgtcgt acagacgaga actagagaaa    240

taccgtgacc tggatgaaga tgaaatcctt ggagccctaa cagaggaaga gctgaggacc    300

ctggaaaatg agctggatga gctggaccct gataatgcac tgctgcctgc aggcctgagg    360

cagaaggatc agaccaccaa ggcgcccacg ggccccttta aaagagagga gctcttggat    420

cacttggaaa agcaagcaaa ggagtttaag gaccgagaag atctggtccc ctacacaggg    480

gaaaaacgag gaaaggtctg ggttcctaag cagaagccac tggatcctgt gctggaaagt    540

gtgacgctgg aaccggagct ggaggaagcc ttggcaaatg cttcagatgc agaactctgt    600

gacattgcag cgatcctggg catgcacacg ctcatgagta accagcagta ctaccaggcc    660

ctgagcagca gctccatcat gaacaaggag gggctcaaca gcgtgattaa acccacacaa    720

tacaagcctg tgcccgacga agaaccaaat tcaacagacg tagaggaaac gctggaacgg    780

ataaagaaca acgacccaaa acttgaagaa gttaacctca ataatatccg gaatatcccc    840

atccccaccc tcaaggcata tgcagaagcc ctgaaagaaa actcatatgt gaagaagttc    900

agcatcgtgg ggacacggag taatgacccc gtggcgtatg cccttgctga gatgctcaag    960

gagaacaagg tgttgaagac actgaatgtg gaatccaact tcatttctgg agctgggatt   1020

ctgcgcctgg tagaagccct cccatacaac acttctctgg tggaaatgaa aattgacaac   1080

cagagccagc ccctgggcaa caaagtggaa atggagattg tgagcatgtt ggaaaaaaac   1140

gcaacacttc tcaaattcgg ctaccacttt acccagcaag gaccccggct tcgggcatcc   1200

aacgcaatga tgaacaacaa tgaccttgtg aggaagagga ggcttgcgga cctgactggg   1260

cccatcattc ccaagtgccg gagtggtgtc tagtgtgtgg cggtggagtc catgcctttg   1320

aactggatgt gttctattga tgacctgtgc tctgcagggg aaaccagaag gcaaaatgct   1380

ggcagcatga aacccttttg tggttcagtt ctttatgcac taaggtttta ggttgactag   1440

tggttgtagt tgaaaatttt ataaaatacc gttaatgtga agtttttctt tagtcacaga   1500

agttgaatct ggttattatt taaaaactag aagcccccaa accagcagat cttactgaag   1560

atgatgttcc agcagcagcg acttagcccc aggagcccag tttcaatggc cttgctgtgt   1620

ggtgtttcaa gtgcatttaa aatgtgtgac acagaaacgg cacactcttc cacatgcttt   1680

tgaagtatta taaaacactt tattacaaat ttgtcttagc tattagcaaa taaaactgat   1740

tatcattctt tatt                                                     1754


<210>  6127
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6127

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6128
<211>  2848
<212>  DNA
<213>  Homo sapiens

<400>  6128
agctcccgcc cgcccgcggc cgcccgggag ctcgtccagc cccgcgctgc gctcgcccgc     60

ccgctgcccg ccggagcacc gcggcctccg cccgcgtcca tctgcccgcc gcccgcgcct    120

gttccgcagc ccgcgtccgc gccggcccca cagctctgcg tccgggtatt actcagcaca    180

gaaattcagg agacacagac aagttcttcc acgatgtcgt acagacgaga actagagaaa    240

taccgtgacc tggatgaaga tgaaatcctt ggagccctaa cagaggaaga gctgaggacc    300

ctggaaaatg agctggatga gctggaccct gataatgcac tgctgcctgc aggcctgagg    360

cagaaggatc agaccaccaa ggcgcccacg ggccccttta aaagagagga gctcttggat    420

cacttggaaa agcaagcaaa ggagtttaag gaccgagaag atctggtccc ctacacaggg    480

gaaaaacgag gaaaggtctg ggttcctaag cagaagccac tggatcctgt gctggaaagt    540

gtgacgctgg aaccggagct ggaggaagcc ttggcaaatg cttcagatgc agaactctgt    600

gacattgcag cgatcctggg catgcacacg ctcatgagta accagcagta ctaccaggcc    660

ctgagcagca gctccatcat gaacaaggag gggctcaaca gcgtgattaa acccacacaa    720

tacaagcctg tgcccgacga agaaccaaat tcaacagacg tagaggaaac gctggaacgg    780

ataaagaaca acgacccaaa acttgaagaa gttaacctca ataatatccg gaatatcccc    840

atccccaccc tcaaggcata tgcagaagcc ctgaaagaaa actcatatgt gaagaagttc    900

agcatcgtgg ggacacggag taatgacccc gtggcgtatg cccttgctga gatgctcaag    960

gagaacaagg tgttgaagac actgaatgtg gaatccaact tcatttctgg agctgggatt   1020

ctgcgcctgg tagaagccct cccatacaac acttctctgg tggaaatgaa aattgacaac   1080

cagagccagc ccctgggcaa caaagtggaa atggagattg tgagcatgtt ggaaaaaaac   1140

gcaacacttc tcaaattcgg ctaccacttt acccagcaag gaccccggct tcgggcatcc   1200

aacgcaatga tgaacaacaa tgaccttgtg aggaagagga ggcttgcgga cctgactggg   1260

cccatcattc ccaagtgccg gagtggtgtc tagtgtgtgg cggtggagtc catgcctttg   1320

aactggatgt gttctattga tgacctgtgc tctgcagggg aaaccagaag gcaaaatgct   1380

ggcagcatga aacccttttg tggttcagtt ctttatgcac taaggtttta ggttgactag   1440

tggttgtagt tgaaaatttt ataaaatacc gttaatgtga agtttttctt tagtcacaga   1500

agttgaatct ggttattatt taaaaactag aagcccccaa accagcagat cttactgaag   1560

atgatgttcc agcagcagcg acttagcccc aggagcccag tttcaatggc cttgctgtgt   1620

ggtgtttcaa gtgcatttaa aatgtgtgac acagaaacgg cacactcttc cacatgcttt   1680

tgaagtatta taaaacactt tattacaaat ttgtcttagc tattagcaaa taaaactgat   1740

tatcattctt tattaaccct ccttggaatt ttgaaaacct cgattaaagt tgccaaattg   1800

attactggat ccagaacaca attttcccct cagaacagat agacagactg aagccactga   1860

actctgccag gagtcaacat gagattcctt ttgctggata tgcagaaatg ataggaaaaa   1920

aaccaatggt gaaatttcaa gtttcaaaaa ccaacctttc attaccaatc ccaggcaaca   1980

aacatgtccc tgagtgttct ttaagaacat ttgggattta tgtacaattt aatactggag   2040

ttagaacttt ttccttattg aatgccaacc ttatgatgga tgtgaaaatc tacggccaaa   2100

tacttttgaa aacacctttc tatattgcac agtgggcaaa tggcttatgt gaggtaagac   2160

actagaggga taaatttcca gatcaacatg gctatggtat ttagtaatgg cccagcttag   2220

agacttcagc tactgatctc atcacttatt agacaaattg ctgctgacct tacgcctgta   2280

tattaagcct ccgcaggatg ccggacaatg gtgaagaaac tccagatatc aaggaattgg   2340

gaaatcctgg ccaaaccacc ccaagatgat tacactgaaa tgtagtatta gtactgctgc   2400

cagatctctt tttaacatca tgtgcgtctc ttgggatcca gcaaaagtgt taagccacaa   2460

tgcccttgtg ccttttaata taccacagtg ccagttaaac taatattttt gtttgttgct   2520

tttgggagtt attttcatta gtgatttcag caaatctcat gataaaggac aaggtcaaga   2580

actccagagc actgagcaga gaggctggtg atgaaaaggt gaaggcctgc gcactgaact   2640

gtaaggcagt gggcagtaca gggtaactgg aggcggggcc agggcctcag cgctatggaa   2700

gagtgtccac tgaggctgca catggcccag gagtggcacc atgttgcagg gacaaccatc   2760

cccatttggc ttctccttaa aacacaattg cagctgcatt ctgcatcgct gaaaactgca   2820

atataatatt aaatctgttg gtctatgc                                      2848


<210>  6129
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6129

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6130
<211>  3342
<212>  DNA
<213>  Homo sapiens

<400>  6130
agctcccgcc cgcccgcggc cgcccgggag ctcgtccagc cccgcgctgc gctcgcccgc     60

ccgctgcccg ccggagcacc gcggcctccg cccgcgtcca tctgcccgcc gcccgcgcct    120

gttccgcagc ccgcgtccgc gccggcccca cagctctgcg tccgggtatt actcagcaca    180

gaaattcagg agacacagac aagttcttcc acgatgtcgt acagacgaga actagagaaa    240

taccgtgacc tggatgaaga tgaaatcctt ggagccctaa cagaggaaga gctgaggacc    300

ctggaaaatg agctggatga gctggaccct gataatgcac tgctgcctgc aggcctgagg    360

cagaaggatc agaccaccaa ggcgcccacg ggccccttta aaagagagga gctcttggat    420

cacttggaaa agcaagcaaa ggagtttaag gaccgagaag atctggtccc ctacacaggg    480

gaaaaacgag gaaaggtctg ggttcctaag cagaagccac tggatcctgt gctggaaagt    540

gtgacgctgg aaccggagct ggaggaagcc ttggcaaatg cttcagatgc agaactctgt    600

gacattgcag cgatcctggg catgcacacg ctcatgagta accagcagta ctaccaggcc    660

ctgagcagca gctccatcat gaacaaggag gggctcaaca gcgtgattaa acccacacaa    720

tacaagcctg tgcccgacga agaaccaaat tcaacagacg tagaggaaac gctggaacgg    780

ataaagaaca acgacccaaa acttgaagaa gttaacctca ataatatccg gaatatcccc    840

atccccaccc tcaaggcata tgcagaagcc ctgaaagaaa actcatatgt gaagaagttc    900

agcatcgtgg ggacacggag taatgacccc gtggcgtatg cccttgctga gatgctcaag    960

gagaacaagg tgttgaagac actgaatgtg gaatccaact tcatttctgg agctgggatt   1020

ctgcgcctgg tagaagccct cccatacaac acttctctgg tggaaatgaa aattgacaac   1080

cagagccagc ccctgggcaa caaagtggaa atggagattg tgagcatgtt ggaaaaaaac   1140

gcaacacttc tcaaattcgg ctaccacttt acccagcaag gaccccggct tcgggcatcc   1200

aacgcaatga tgaacaacaa tgaccttgtg aggaagagga ggcttgcgga cctgactggg   1260

cccatcattc ccaagtgccg gagtggtgtc tagtgtgtgg cggtggagtc catgcctttg   1320

aactggatgt gttctattga tgacctgtgc tctgcagggg aaaccagaag gcaaaatgct   1380

ggcagcatga aacccttttg tggttcagtt ctttatgcac taaggtttta ggttgactag   1440

tggttgtagt tgaaaatttt ataaaatacc gttaatgtga agtttttctt tagtcacaga   1500

agttgaatct ggttattatt taaaaactag aagcccccaa accagcagat cttactgaag   1560

atgatgttcc agcagcagcg acttagcccc aggagcccag tttcaatggc cttgctgtgt   1620

ggtgtttcaa gtgcatttaa aatgtgtgac acagaaacgg cacactcttc cacatgcttt   1680

tgaagtatta taaaacactt tattacaaat ttgtcttagc tattagcaaa taaaactgat   1740

tatcattctt tattaaccct ccttggaatt ttgaaaacct cgattaaagt tgccaaattg   1800

attactggat ccagaacaca attttcccct cagaacagat agacagactg aagccactga   1860

actctgccag gagtcaacat gagattcctt ttgctggata tgcagaaatg ataggaaaaa   1920

aaccaatggt gaaatttcaa gtttcaaaaa ccaacctttc attaccaatc ccaggcaaca   1980

aacatgtccc tgagtgttct ttaagaacat ttgggattta tgtacaattt aatactggag   2040

ttagaacttt ttccttattg aatgccaacc ttatgatgga tgtgaaaatc tacggccaaa   2100

tacttttgaa aacacctttc tatattgcac agtgggcaaa tggcttatgt gaggtaagac   2160

actagaggga taaatttcca gatcaacatg gctatggtat ttagtaatgg cccagcttag   2220

agacttcagc tactgatctc atcacttatt agacaaattg ctgctgacct tacgcctgta   2280

tattaagcct ccgcaggatg ccggacaatg gtgaagaaac tccagatatc aaggaattgg   2340

gaaatcctgg ccaaaccacc ccaagatgat tacactgaaa tgtagtatta gtactgctgc   2400

cagatctctt tttaacatca tgtgcgtctc ttgggatcca gcaaaagtgt taagccacaa   2460

tgcccttgtg ccttttaata taccacagtg ccagttaaac taatattttt gtttgttgct   2520

tttgggagtt attttcatta gtgatttcag caaatctcat gataaaggac aaggtcaaga   2580

actccagagc actgagcaga gaggctggtg atgaaaaggt gaaggcctgc gcactgaact   2640

gtaaggcagt gggcagtaca gggtaactgg aggcggggcc agggcctcag cgctatggaa   2700

gagtgtccac tgaggctgca catggcccag gagtggcacc atgttgcagg gacaaccatc   2760

cccatttggc ttctccttaa aacacaattg cagctgcatt ctgcatcgct gaaaactgca   2820

atataatatt aaatctgttg gtctatgcat ggctgcgtat gtgtttcttg gaacctgtgt   2880

gacagggaca tgtgcctggc acactggcca gaagactggg cagccaccat ggcagtgctg   2940

gatgacctca gtaagaatgt gtcatgtatt ccaggtgctg atctaaaaac tgtggctcaa   3000

atgtcaccga gcttatatga agctcccaga gagaacattt aaaagctcag agagtaagtg   3060

ctggggaaag cagagctatc agaggaaatc tctcatagaa acgaaaccaa accaacagaa   3120

aatgaagaag gccacatctt taaggccacc tctgcctcta tcagatgagc tgctggtcta   3180

gatcaggggc tggcaaactt ttctgtaaaa ggccagacag taaaaatttc cgattttgca   3240

ggccacatag tgtctgttgc aactattcaa ctctgccata gatcatgtgt aaaggaatgg   3300

gtgtggctgt tcaataaact atacagttga cccttgaaca at                      3342


<210>  6131
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6131

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6132
<211>  3483
<212>  DNA
<213>  Homo sapiens

<400>  6132
agctcccgcc cgcccgcggc cgcccgggag ctcgtccagc cccgcgctgc gctcgcccgc     60

ccgctgcccg ccggagcacc gcggcctccg cccgcgtcca tctgcccgcc gcccgcgcct    120

gttccgcagc ccgcgtccgc gccggcccca cagctctgcg tccgggtatt actcagcaca    180

gaaattcagg agacacagac aagttcttcc acgatgtcgt acagacgaga actagagaaa    240

taccgtgacc tggatgaaga tgaaatcctt ggagccctaa cagaggaaga gctgaggacc    300

ctggaaaatg agctggatga gctggaccct gataatgcac tgctgcctgc aggcctgagg    360

cagaaggatc agaccaccaa ggcgcccacg ggccccttta aaagagagga gctcttggat    420

cacttggaaa agcaagcaaa ggagtttaag gaccgagaag atctggtccc ctacacaggg    480

gaaaaacgag gaaaggtctg ggttcctaag cagaagccac tggatcctgt gctggaaagt    540

gtgacgctgg aaccggagct ggaggaagcc ttggcaaatg cttcagatgc agaactctgt    600

gacattgcag cgatcctggg catgcacacg ctcatgagta accagcagta ctaccaggcc    660

ctgagcagca gctccatcat gaacaaggag gggctcaaca gcgtgattaa acccacacaa    720

tacaagcctg tgcccgacga agaaccaaat tcaacagacg tagaggaaac gctggaacgg    780

ataaagaaca acgacccaaa acttgaagaa gttaacctca ataatatccg gaatatcccc    840

atccccaccc tcaaggcata tgcagaagcc ctgaaagaaa actcatatgt gaagaagttc    900

agcatcgtgg ggacacggag taatgacccc gtggcgtatg cccttgctga gatgctcaag    960

gagaacaagg tgttgaagac actgaatgtg gaatccaact tcatttctgg agctgggatt   1020

ctgcgcctgg tagaagccct cccatacaac acttctctgg tggaaatgaa aattgacaac   1080

cagagccagc ccctgggcaa caaagtggaa atggagattg tgagcatgtt ggaaaaaaac   1140

gcaacacttc tcaaattcgg ctaccacttt acccagcaag gaccccggct tcgggcatcc   1200

aacgcaatga tgaacaacaa tgaccttgtg aggaagagga ggcttgcgga cctgactggg   1260

cccatcattc ccaagtgccg gagtggtgtc tagtgtgtgg cggtggagtc catgcctttg   1320

aactggatgt gttctattga tgacctgtgc tctgcagggg aaaccagaag gcaaaatgct   1380

ggcagcatga aacccttttg tggttcagtt ctttatgcac taaggtttta ggttgactag   1440

tggttgtagt tgaaaatttt ataaaatacc gttaatgtga agtttttctt tagtcacaga   1500

agttgaatct ggttattatt taaaaactag aagcccccaa accagcagat cttactgaag   1560

atgatgttcc agcagcagcg acttagcccc aggagcccag tttcaatggc cttgctgtgt   1620

ggtgtttcaa gtgcatttaa aatgtgtgac acagaaacgg cacactcttc cacatgcttt   1680

tgaagtatta taaaacactt tattacaaat ttgtcttagc tattagcaaa taaaactgat   1740

tatcattctt tattaaccct ccttggaatt ttgaaaacct cgattaaagt tgccaaattg   1800

attactggat ccagaacaca attttcccct cagaacagat agacagactg aagccactga   1860

actctgccag gagtcaacat gagattcctt ttgctggata tgcagaaatg ataggaaaaa   1920

aaccaatggt gaaatttcaa gtttcaaaaa ccaacctttc attaccaatc ccaggcaaca   1980

aacatgtccc tgagtgttct ttaagaacat ttgggattta tgtacaattt aatactggag   2040

ttagaacttt ttccttattg aatgccaacc ttatgatgga tgtgaaaatc tacggccaaa   2100

tacttttgaa aacacctttc tatattgcac agtgggcaaa tggcttatgt gaggtaagac   2160

actagaggga taaatttcca gatcaacatg gctatggtat ttagtaatgg cccagcttag   2220

agacttcagc tactgatctc atcacttatt agacaaattg ctgctgacct tacgcctgta   2280

tattaagcct ccgcaggatg ccggacaatg gtgaagaaac tccagatatc aaggaattgg   2340

gaaatcctgg ccaaaccacc ccaagatgat tacactgaaa tgtagtatta gtactgctgc   2400

cagatctctt tttaacatca tgtgcgtctc ttgggatcca gcaaaagtgt taagccacaa   2460

tgcccttgtg ccttttaata taccacagtg ccagttaaac taatattttt gtttgttgct   2520

tttgggagtt attttcatta gtgatttcag caaatctcat gataaaggac aaggtcaaga   2580

actccagagc actgagcaga gaggctggtg atgaaaaggt gaaggcctgc gcactgaact   2640

gtaaggcagt gggcagtaca gggtaactgg aggcggggcc agggcctcag cgctatggaa   2700

gagtgtccac tgaggctgca catggcccag gagtggcacc atgttgcagg gacaaccatc   2760

cccatttggc ttctccttaa aacacaattg cagctgcatt ctgcatcgct gaaaactgca   2820

atataatatt aaatctgttg gtctatgcat ggctgcgtat gtgtttcttg gaacctgtgt   2880

gacagggaca tgtgcctggc acactggcca gaagactggg cagccaccat ggcagtgctg   2940

gatgacctca gtaagaatgt gtcatgtatt ccaggtgctg atctaaaaac tgtggctcaa   3000

atgtcaccga gcttatatga agctcccaga gagaacattt aaaagctcag agagtaagtg   3060

ctggggaaag cagagctatc agaggaaatc tctcatagaa acgaaaccaa accaacagaa   3120

aatgaagaag gccacatctt taaggccacc tctgcctcta tcagatgagc tgctggtcta   3180

gatcaggggc tggcaaactt ttctgtaaaa ggccagacag taaaaatttc cgattttgca   3240

ggccacatag tgtctgttgc aactattcaa ctctgccata gatcatgtgt aaaggaatgg   3300

gtgtggctgt tcaataaact atacagttga cccttgaaca atatgggttt gaactgcatg   3360

gctgcactta tatatggatt tttttcaacc atacaggttg aaaatacagt attggcaggg   3420

ggcgaaacct gcgtacatgg agggctgatt tatcacatac gtgggttctg tagggcccac   3480

tgt                                                                 3483


<210>  6133
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6133

Met Ser Tyr Arg Arg Glu Leu Glu Lys Tyr Arg Asp Leu Asp Glu Asp 
1               5                   10                  15


Glu Ile Leu Gly Ala Leu Thr Glu Glu Glu Leu Arg Thr Leu Glu Asn 
            20                  25                  30


Glu Leu Asp Glu Leu Asp Pro Asp Asn Ala Leu Leu Pro Ala Gly Leu 
        35                  40                  45


Arg Gln Lys Asp Gln Thr Thr Lys Ala Pro Thr Gly Pro Phe Lys Arg 
    50                  55                  60


Glu Glu Leu Leu Asp His Leu Glu Lys Gln Ala Lys Glu Phe Lys Asp 
65                  70                  75                  80


Arg Glu Asp Leu Val Pro Tyr Thr Gly Glu Lys Arg Gly Lys Val Trp 
                85                  90                  95


Val Pro Lys Gln Lys Pro Leu Asp Pro Val Leu Glu Ser Val Thr Leu 
            100                 105                 110


Glu Pro Glu Leu Glu Glu Ala Leu Ala Asn Ala Ser Asp Ala Glu Leu 
        115                 120                 125


Cys Asp Ile Ala Ala Ile Leu Gly Met His Thr Leu Met Ser Asn Gln 
    130                 135                 140


Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu Gly 
145                 150                 155                 160


Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp Glu 
                165                 170                 175


Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys Asn 
            180                 185                 190


Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn Ile 
        195                 200                 205


Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn Ser 
    210                 215                 220


Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro Val 
225                 230                 235                 240


Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys Thr 
                245                 250                 255


Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg Leu 
            260                 265                 270


Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile Asp 
        275                 280                 285


Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val Ser 
    290                 295                 300


Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe Thr 
305                 310                 315                 320


Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn Asn 
                325                 330                 335


Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile Ile 
            340                 345                 350


Pro Lys Cys Arg Ser Gly Val 
        355


<210>  6134
<211>  2515
<212>  DNA
<213>  Homo sapiens

<400>  6134
gtgccaggtc agagctgcaa ctctgtgcta cgtttctgtg tggctttctt gaaactactt     60

ctctttattt ttgttggcgt ggctatttat tgttatctgt aacgacgcaa tatgctgccg    120

aagtctggga aggagagggg agctgtaagt ctacaccagt gttaactggc taaccttgga    180

tgcctgtcat ttgatgttgg acatttgaaa gatggcagca tctctgggga aggagggact    240

gaacactttt gaccacctac catgtcccag gttctatcga tcctgggcat gcacacgctc    300

atgagtaacc agcagtacta ccaggccctg agcagcagct ccatcatgaa caaggagggg    360

ctcaacagcg tgattaaacc cacacaatac aagcctgtgc ccgacgaaga accaaattca    420

acagacgtag aggaaacgct ggaacggata aagaacaacg acccaaaact tgaagaagtt    480

aacctcaata atatccggaa tatccccatc cccaccctca aggcatatgc agaagccctg    540

aaagaaaact catatgtgaa gaagttcagc atcgtgggga cacggagtaa tgaccccgtg    600

gcgtatgccc ttgctgagat gctcaaggag aacaaggtgt tgaagacact gaatgtggaa    660

tccaacttca tttctggagc tgggattctg cgcctggtag aagccctccc atacaacact    720

tctctggtgg aaatgaaaat tgacaaccag agccagcccc tgggcaacaa agtggaaatg    780

gagattgtga gcatgttgga aaaaaacgca acacttctca aattcggcta ccactttacc    840

cagcaaggac cccggcttcg ggcatccaac gcaatgatga acaacaatga ccttgtgagg    900

aagaggaggc ttgcggacct gactgggccc atcattccca agtgccggag tggtgtctag    960

tgtgtggcgg tggagtccat gcctttgaac tggatgtgtt ctattgatga cctgtgctct   1020

gcaggggaaa ccagaaggca aaatgctggc agcatgaaac ccttttgtgg ttcagttctt   1080

tatgcactaa ggttttaggt tgactagtgg ttgtagttga aaattttata aaataccgtt   1140

aatgtgaagt ttttctttag tcacagaagt tgaatctggt tattatttaa aaactagaag   1200

cccccaaacc agcagatctt actgaagatg atgttccagc agcagcgact tagccccagg   1260

agcccagttt caatggcctt gctgtgtggt gtttcaagtg catttaaaat gtgtgacaca   1320

gaaacggcac actcttccac atgcttttga agtattataa aacactttat tacaaatttg   1380

tcttagctat tagcaaataa aactgattat cattctttat taaccctcct tggaattttg   1440

aaaacctcga ttaaagttgc caaattgatt actggatcca gaacacaatt ttcccctcag   1500

aacagataga cagactgaag ccactgaact ctgccaggag tcaacatgag attccttttg   1560

ctggatatgc agaaatgata ggaaaaaaac caatggtgaa atttcaagtt tcaaaaacca   1620

acctttcatt accaatccca ggcaacaaac atgtccctga gtgttcttta agaacatttg   1680

ggatttatgt acaatttaat actggagtta gaactttttc cttattgaat gccaacctta   1740

tgatggatgt gaaaatctac ggccaaatac ttttgaaaac acctttctat attgcacagt   1800

gggcaaatgg cttatgtgag gtaagacact agagggataa atttccagat caacatggct   1860

atggtattta gtaatggccc agcttagaga cttcagctac tgatctcatc acttattaga   1920

caaattgctg ctgaccttac gcctgtatat taagcctccg caggatgccg gacaatggtg   1980

aagaaactcc agatatcaag gaattgggaa atcctggcca aaccacccca agatgattac   2040

actgaaatgt agtattagta ctgctgccag atctcttttt aacatcatgt gcgtctcttg   2100

ggatccagca aaagtgttaa gccacaatgc ccttgtgcct tttaatatac cacagtgcca   2160

gttaaactaa tatttttgtt tgttgctttt gggagttatt ttcattagtg atttcagcaa   2220

atctcatgat aaaggacaag gtcaagaact ccagagcact gagcagagag gctggtgatg   2280

aaaaggtgaa ggcctgcgca ctgaactgta aggcagtggg cagtacaggg taactggagg   2340

cggggccagg gcctcagcgc tatggaagag tgtccactga ggctgcacat ggcccaggag   2400

tggcaccatg ttgcagggac aaccatcccc atttggcttc tccttaaaac acaattgcag   2460

ctgcattctg catcgctgaa aactgcaata taatattaaa tctgttggtc tatgc        2515


<210>  6135
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  6135

Met Ser Gln Val Leu Ser Ile Leu Gly Met His Thr Leu Met Ser Asn 
1               5                   10                  15


Gln Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu 
            20                  25                  30


Gly Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp 
        35                  40                  45


Glu Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys 
    50                  55                  60


Asn Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn 
65                  70                  75                  80


Ile Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn 
                85                  90                  95


Ser Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro 
            100                 105                 110


Val Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys 
        115                 120                 125


Thr Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg 
    130                 135                 140


Leu Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile 
145                 150                 155                 160


Asp Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val 
                165                 170                 175


Ser Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe 
            180                 185                 190


Thr Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn 
        195                 200                 205


Asn Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile 
    210                 215                 220


Ile Pro Lys Cys Arg Ser Gly Val 
225                 230


<210>  6136
<211>  3009
<212>  DNA
<213>  Homo sapiens

<400>  6136
gtgccaggtc agagctgcaa ctctgtgcta cgtttctgtg tggctttctt gaaactactt     60

ctctttattt ttgttggcgt ggctatttat tgttatctgt aacgacgcaa tatgctgccg    120

aagtctggga aggagagggg agctgtaagt ctacaccagt gttaactggc taaccttgga    180

tgcctgtcat ttgatgttgg acatttgaaa gatggcagca tctctgggga aggagggact    240

gaacactttt gaccacctac catgtcccag gttctatcga tcctgggcat gcacacgctc    300

atgagtaacc agcagtacta ccaggccctg agcagcagct ccatcatgaa caaggagggg    360

ctcaacagcg tgattaaacc cacacaatac aagcctgtgc ccgacgaaga accaaattca    420

acagacgtag aggaaacgct ggaacggata aagaacaacg acccaaaact tgaagaagtt    480

aacctcaata atatccggaa tatccccatc cccaccctca aggcatatgc agaagccctg    540

aaagaaaact catatgtgaa gaagttcagc atcgtgggga cacggagtaa tgaccccgtg    600

gcgtatgccc ttgctgagat gctcaaggag aacaaggtgt tgaagacact gaatgtggaa    660

tccaacttca tttctggagc tgggattctg cgcctggtag aagccctccc atacaacact    720

tctctggtgg aaatgaaaat tgacaaccag agccagcccc tgggcaacaa agtggaaatg    780

gagattgtga gcatgttgga aaaaaacgca acacttctca aattcggcta ccactttacc    840

cagcaaggac cccggcttcg ggcatccaac gcaatgatga acaacaatga ccttgtgagg    900

aagaggaggc ttgcggacct gactgggccc atcattccca agtgccggag tggtgtctag    960

tgtgtggcgg tggagtccat gcctttgaac tggatgtgtt ctattgatga cctgtgctct   1020

gcaggggaaa ccagaaggca aaatgctggc agcatgaaac ccttttgtgg ttcagttctt   1080

tatgcactaa ggttttaggt tgactagtgg ttgtagttga aaattttata aaataccgtt   1140

aatgtgaagt ttttctttag tcacagaagt tgaatctggt tattatttaa aaactagaag   1200

cccccaaacc agcagatctt actgaagatg atgttccagc agcagcgact tagccccagg   1260

agcccagttt caatggcctt gctgtgtggt gtttcaagtg catttaaaat gtgtgacaca   1320

gaaacggcac actcttccac atgcttttga agtattataa aacactttat tacaaatttg   1380

tcttagctat tagcaaataa aactgattat cattctttat taaccctcct tggaattttg   1440

aaaacctcga ttaaagttgc caaattgatt actggatcca gaacacaatt ttcccctcag   1500

aacagataga cagactgaag ccactgaact ctgccaggag tcaacatgag attccttttg   1560

ctggatatgc agaaatgata ggaaaaaaac caatggtgaa atttcaagtt tcaaaaacca   1620

acctttcatt accaatccca ggcaacaaac atgtccctga gtgttcttta agaacatttg   1680

ggatttatgt acaatttaat actggagtta gaactttttc cttattgaat gccaacctta   1740

tgatggatgt gaaaatctac ggccaaatac ttttgaaaac acctttctat attgcacagt   1800

gggcaaatgg cttatgtgag gtaagacact agagggataa atttccagat caacatggct   1860

atggtattta gtaatggccc agcttagaga cttcagctac tgatctcatc acttattaga   1920

caaattgctg ctgaccttac gcctgtatat taagcctccg caggatgccg gacaatggtg   1980

aagaaactcc agatatcaag gaattgggaa atcctggcca aaccacccca agatgattac   2040

actgaaatgt agtattagta ctgctgccag atctcttttt aacatcatgt gcgtctcttg   2100

ggatccagca aaagtgttaa gccacaatgc ccttgtgcct tttaatatac cacagtgcca   2160

gttaaactaa tatttttgtt tgttgctttt gggagttatt ttcattagtg atttcagcaa   2220

atctcatgat aaaggacaag gtcaagaact ccagagcact gagcagagag gctggtgatg   2280

aaaaggtgaa ggcctgcgca ctgaactgta aggcagtggg cagtacaggg taactggagg   2340

cggggccagg gcctcagcgc tatggaagag tgtccactga ggctgcacat ggcccaggag   2400

tggcaccatg ttgcagggac aaccatcccc atttggcttc tccttaaaac acaattgcag   2460

ctgcattctg catcgctgaa aactgcaata taatattaaa tctgttggtc tatgcatggc   2520

tgcgtatgtg tttcttggaa cctgtgtgac agggacatgt gcctggcaca ctggccagaa   2580

gactgggcag ccaccatggc agtgctggat gacctcagta agaatgtgtc atgtattcca   2640

ggtgctgatc taaaaactgt ggctcaaatg tcaccgagct tatatgaagc tcccagagag   2700

aacatttaaa agctcagaga gtaagtgctg gggaaagcag agctatcaga ggaaatctct   2760

catagaaacg aaaccaaacc aacagaaaat gaagaaggcc acatctttaa ggccacctct   2820

gcctctatca gatgagctgc tggtctagat caggggctgg caaacttttc tgtaaaaggc   2880

cagacagtaa aaatttccga ttttgcaggc cacatagtgt ctgttgcaac tattcaactc   2940

tgccatagat catgtgtaaa ggaatgggtg tggctgttca ataaactata cagttgaccc   3000

ttgaacaat                                                           3009


<210>  6137
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  6137

Met Ser Gln Val Leu Ser Ile Leu Gly Met His Thr Leu Met Ser Asn 
1               5                   10                  15


Gln Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu 
            20                  25                  30


Gly Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp 
        35                  40                  45


Glu Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys 
    50                  55                  60


Asn Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn 
65                  70                  75                  80


Ile Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn 
                85                  90                  95


Ser Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro 
            100                 105                 110


Val Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys 
        115                 120                 125


Thr Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg 
    130                 135                 140


Leu Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile 
145                 150                 155                 160


Asp Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val 
                165                 170                 175


Ser Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe 
            180                 185                 190


Thr Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn 
        195                 200                 205


Asn Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile 
    210                 215                 220


Ile Pro Lys Cys Arg Ser Gly Val 
225                 230


<210>  6138
<211>  3150
<212>  DNA
<213>  Homo sapiens

<400>  6138
gtgccaggtc agagctgcaa ctctgtgcta cgtttctgtg tggctttctt gaaactactt     60

ctctttattt ttgttggcgt ggctatttat tgttatctgt aacgacgcaa tatgctgccg    120

aagtctggga aggagagggg agctgtaagt ctacaccagt gttaactggc taaccttgga    180

tgcctgtcat ttgatgttgg acatttgaaa gatggcagca tctctgggga aggagggact    240

gaacactttt gaccacctac catgtcccag gttctatcga tcctgggcat gcacacgctc    300

atgagtaacc agcagtacta ccaggccctg agcagcagct ccatcatgaa caaggagggg    360

ctcaacagcg tgattaaacc cacacaatac aagcctgtgc ccgacgaaga accaaattca    420

acagacgtag aggaaacgct ggaacggata aagaacaacg acccaaaact tgaagaagtt    480

aacctcaata atatccggaa tatccccatc cccaccctca aggcatatgc agaagccctg    540

aaagaaaact catatgtgaa gaagttcagc atcgtgggga cacggagtaa tgaccccgtg    600

gcgtatgccc ttgctgagat gctcaaggag aacaaggtgt tgaagacact gaatgtggaa    660

tccaacttca tttctggagc tgggattctg cgcctggtag aagccctccc atacaacact    720

tctctggtgg aaatgaaaat tgacaaccag agccagcccc tgggcaacaa agtggaaatg    780

gagattgtga gcatgttgga aaaaaacgca acacttctca aattcggcta ccactttacc    840

cagcaaggac cccggcttcg ggcatccaac gcaatgatga acaacaatga ccttgtgagg    900

aagaggaggc ttgcggacct gactgggccc atcattccca agtgccggag tggtgtctag    960

tgtgtggcgg tggagtccat gcctttgaac tggatgtgtt ctattgatga cctgtgctct   1020

gcaggggaaa ccagaaggca aaatgctggc agcatgaaac ccttttgtgg ttcagttctt   1080

tatgcactaa ggttttaggt tgactagtgg ttgtagttga aaattttata aaataccgtt   1140

aatgtgaagt ttttctttag tcacagaagt tgaatctggt tattatttaa aaactagaag   1200

cccccaaacc agcagatctt actgaagatg atgttccagc agcagcgact tagccccagg   1260

agcccagttt caatggcctt gctgtgtggt gtttcaagtg catttaaaat gtgtgacaca   1320

gaaacggcac actcttccac atgcttttga agtattataa aacactttat tacaaatttg   1380

tcttagctat tagcaaataa aactgattat cattctttat taaccctcct tggaattttg   1440

aaaacctcga ttaaagttgc caaattgatt actggatcca gaacacaatt ttcccctcag   1500

aacagataga cagactgaag ccactgaact ctgccaggag tcaacatgag attccttttg   1560

ctggatatgc agaaatgata ggaaaaaaac caatggtgaa atttcaagtt tcaaaaacca   1620

acctttcatt accaatccca ggcaacaaac atgtccctga gtgttcttta agaacatttg   1680

ggatttatgt acaatttaat actggagtta gaactttttc cttattgaat gccaacctta   1740

tgatggatgt gaaaatctac ggccaaatac ttttgaaaac acctttctat attgcacagt   1800

gggcaaatgg cttatgtgag gtaagacact agagggataa atttccagat caacatggct   1860

atggtattta gtaatggccc agcttagaga cttcagctac tgatctcatc acttattaga   1920

caaattgctg ctgaccttac gcctgtatat taagcctccg caggatgccg gacaatggtg   1980

aagaaactcc agatatcaag gaattgggaa atcctggcca aaccacccca agatgattac   2040

actgaaatgt agtattagta ctgctgccag atctcttttt aacatcatgt gcgtctcttg   2100

ggatccagca aaagtgttaa gccacaatgc ccttgtgcct tttaatatac cacagtgcca   2160

gttaaactaa tatttttgtt tgttgctttt gggagttatt ttcattagtg atttcagcaa   2220

atctcatgat aaaggacaag gtcaagaact ccagagcact gagcagagag gctggtgatg   2280

aaaaggtgaa ggcctgcgca ctgaactgta aggcagtggg cagtacaggg taactggagg   2340

cggggccagg gcctcagcgc tatggaagag tgtccactga ggctgcacat ggcccaggag   2400

tggcaccatg ttgcagggac aaccatcccc atttggcttc tccttaaaac acaattgcag   2460

ctgcattctg catcgctgaa aactgcaata taatattaaa tctgttggtc tatgcatggc   2520

tgcgtatgtg tttcttggaa cctgtgtgac agggacatgt gcctggcaca ctggccagaa   2580

gactgggcag ccaccatggc agtgctggat gacctcagta agaatgtgtc atgtattcca   2640

ggtgctgatc taaaaactgt ggctcaaatg tcaccgagct tatatgaagc tcccagagag   2700

aacatttaaa agctcagaga gtaagtgctg gggaaagcag agctatcaga ggaaatctct   2760

catagaaacg aaaccaaacc aacagaaaat gaagaaggcc acatctttaa ggccacctct   2820

gcctctatca gatgagctgc tggtctagat caggggctgg caaacttttc tgtaaaaggc   2880

cagacagtaa aaatttccga ttttgcaggc cacatagtgt ctgttgcaac tattcaactc   2940

tgccatagat catgtgtaaa ggaatgggtg tggctgttca ataaactata cagttgaccc   3000

ttgaacaata tgggtttgaa ctgcatggct gcacttatat atggattttt ttcaaccata   3060

caggttgaaa atacagtatt ggcagggggc gaaacctgcg tacatggagg gctgatttat   3120

cacatacgtg ggttctgtag ggcccactgt                                    3150


<210>  6139
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  6139

Met Ser Gln Val Leu Ser Ile Leu Gly Met His Thr Leu Met Ser Asn 
1               5                   10                  15


Gln Gln Tyr Tyr Gln Ala Leu Ser Ser Ser Ser Ile Met Asn Lys Glu 
            20                  25                  30


Gly Leu Asn Ser Val Ile Lys Pro Thr Gln Tyr Lys Pro Val Pro Asp 
        35                  40                  45


Glu Glu Pro Asn Ser Thr Asp Val Glu Glu Thr Leu Glu Arg Ile Lys 
    50                  55                  60


Asn Asn Asp Pro Lys Leu Glu Glu Val Asn Leu Asn Asn Ile Arg Asn 
65                  70                  75                  80


Ile Pro Ile Pro Thr Leu Lys Ala Tyr Ala Glu Ala Leu Lys Glu Asn 
                85                  90                  95


Ser Tyr Val Lys Lys Phe Ser Ile Val Gly Thr Arg Ser Asn Asp Pro 
            100                 105                 110


Val Ala Tyr Ala Leu Ala Glu Met Leu Lys Glu Asn Lys Val Leu Lys 
        115                 120                 125


Thr Leu Asn Val Glu Ser Asn Phe Ile Ser Gly Ala Gly Ile Leu Arg 
    130                 135                 140


Leu Val Glu Ala Leu Pro Tyr Asn Thr Ser Leu Val Glu Met Lys Ile 
145                 150                 155                 160


Asp Asn Gln Ser Gln Pro Leu Gly Asn Lys Val Glu Met Glu Ile Val 
                165                 170                 175


Ser Met Leu Glu Lys Asn Ala Thr Leu Leu Lys Phe Gly Tyr His Phe 
            180                 185                 190


Thr Gln Gln Gly Pro Arg Leu Arg Ala Ser Asn Ala Met Met Asn Asn 
        195                 200                 205


Asn Asp Leu Val Arg Lys Arg Arg Leu Ala Asp Leu Thr Gly Pro Ile 
    210                 215                 220


Ile Pro Lys Cys Arg Ser Gly Val 
225                 230


<210>  6140
<211>  889
<212>  DNA
<213>  Homo sapiens

<400>  6140
aatatagaca actttacata caaatcgtct attttgtgac cagggttttt tttctttttt     60

tttctttcca ttcaatattg gttcatggcc atctttacat gctatggcca aggatttgca    120

ccatcatttt agagctgccc acattctatt tagtatggtt gaactatcat ttatctgagc    180

aactctctat gaattctttt tttttcaatt tttatttatt ttttgttttt tggagacaga    240

gtctcgctct gtcgcctggg ctggagggca gtggcacaat ttcggctcgc tgcaaactct    300

gcctcccggg ttcaagccat tctccctgtc tctactaaaa atacaaaaaa ttagccgggc    360

atggtggcag gcacctgtaa tcccagctcc ttgggaggct gaggcaggag gatcgcttga    420

acccgggagg cagaaattgc agtgagccaa gaccacacca ttgcacttca gtgtgggcaa    480

caagaaaact ccatcaaaaa aaaaagaaga agaaaaaaag aaaaggctac tcctttcctc    540

acagccaccc aagccagaaa tctgggcctg ttcctagatg ctgcctccac cccagccagc    600

cagtcacctc cttgccaatc ccagtgtcct gccgtgtatg ttgagccctc gtcacagtta    660

tctcctccaa catcctcagg cccccagctc ctccagggca ggcacccctg gcactcatcc    720

caagtctcct tccgaagctt gccttgtcac ccctccactt agaaccctca cttgcctccc    780

attgctctca gtcaggcccc ttgaaatgac tcccaagtct cttaataata gctgactctt    840

acatggcact tactgtgtgt tagagactgt tctgaatact tcccatctc                889


<210>  6141
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  6141

Met Leu Trp Pro Arg Ile Cys Thr Ile Ile Leu Glu Leu Pro Thr Phe 
1               5                   10                  15


Tyr Leu Val Trp Leu Asn Tyr His Leu Ser Glu Gln Leu Ser Met Asn 
            20                  25                  30


Ser Phe Phe Phe Asn Phe Tyr Leu Phe Phe Val Phe Trp Arg Gln Ser 
        35                  40                  45


Leu Ala Leu Ser Pro Gly Leu Glu Gly Ser Gly Thr Ile Ser Ala Arg 
    50                  55                  60


Cys Lys Leu Cys Leu Pro Gly Ser Ser His Ser Pro Cys Leu Tyr 
65                  70                  75


<210>  6142
<211>  3832
<212>  DNA
<213>  Homo sapiens

<400>  6142
ctatgttccc caggcttccc cttgtatttt aatacttacc catcttctag ctttcctgtc     60

tttttctctc ctttactttc tttctcatat gtcgtttctg ttgtccaccc ctcttgccct    120

tttctctttt actcatgcac acacacttag acacattctt cttgctcctt tgcattaaaa    180

atgtatctat tccaacttta ttccataact ttttgctcac acctgcctgt gggttcttag    240

ccttcaacgt gggttcgacc ttaatataga acagtttaca aagcctgtag tcagccacgt    300

acttgcccag ctcctccatg tacagtgaca atagagcagt ggccatttcc tgacctacca    360

gtgaccatac aatggaccag caaattcaca tggcaattta gatcccagtt gcctggtttt    420

tatcactagg gttaggccaa gtatgaggat gcaaaattct ttgactagtt atttctaaac    480

taccaggtct ccattgccct cattttagga ggagggagat tgaggatacc tggaattact    540

ggaattacta agttatttca tcatgatcat caagtagtgt tcttttcaga cagttgtaat    600

tatgaagaga agagatttgg gtggaaagaa acaaagcaac acgtaagtca ggctgggtga    660

gtcatgattg ggttttggtt tttttgtctt tgttttaata taattttttt ggtttggttt    720

taggaatcca tttatcccca ggtgaatttc ataaagaagt agaaaagttt ttatctcagg    780

caaatcaaga acaaagtgat actatccttc ttgattgcag aaacttctat gaaagcaaaa    840

taggacgatt ccaaggctgc ttagccccag acatcaggaa attcagttac ttccctagct    900

acgttgacaa aaatctagaa cttttcagag agaagagagt gctgatgtac tgtaccgggg    960

gcatccgctg tgagcggggt tcagcctacc tcaaagccaa gggagtgtgc aaggaggtgt   1020

tccagctcaa gggtggcatc cacaagtacc tggaagagtt tcctgatggc ttttacaaag   1080

ggaagttgtt tgtttttgat gaacgctatg ctctgtccta caacagtgat gtggtgtcag   1140

agtgttcata ctgtggagcc cgctgggacc agtataaact ctgctctact ccccagtgcc   1200

gccagctcgt tttgacctgc cctgcctgtc aaggacaagg attcacagcc tgttgtgtca   1260

catgtcaaga caaggggagc aggaaagttt caggccctat gcaagacagc tttaaagagg   1320

aatgcgagtg cacagcccga cggccacgca tacctaggga actcttgcag catgtgcgac   1380

agcctgtgag cccagagcca gggcctgatg ctgatgagga tgggccagtg cttatgtgag   1440

cagcaccttt ggcattttcc caggccctcg gtaaaagtag gtttggggtg actatacaga   1500

gaaagcatgg caagactgca gaaacagaga aatcgggaac ttcagttctg gccgctgcca   1560

ccgtggcagc cgtctacact tcacagcggg aggggaggag tcacgttgtc taccacttac   1620

ctgagacatt ctgatttgga tgatgctaga gcacagaaaa taggtgagct gcatgggatc   1680

ccaaagctgc tgagggatag agcctgagcc tggtggccac agcatatgcc ctttctgttc   1740

catgcagctg gggctgttag tagtcattgc ccttgtcagc agaccttcta ccctggtggc   1800

aaacacatga aagctgtggc cctgggagtg gcctcctaaa acaagccact taggtcatct   1860

gccatctacc cttaacctct gtctctcgcc tgaggggaat ctgcaagctg tgcattgggc   1920

ttacctcctg cttttgtaga aataaccatc ctttggtata catggaggat agttccagaa   1980

cgcctgagta tacaaaaacc caatgcatac tcaagtccca cagtgggccc tacagaaccc   2040

acgtatgtga taaatcagcc ctccatgtac gcaggtttcg ccccctgcca atactgtatt   2100

ttcaacctgt atggttgaaa aaaatccata tataagtgca gccatgcagt tcaaacccat   2160

attgttcaag ggtcaactgt atagtttatt gaacagccac acccattcct ttacacatga   2220

tctatggcag agttgaatag ttgcaacaga cactatgtgg cctgcaaaat cggaaatttt   2280

tactgtctgg ccttttacag aaaagtttgc cagcccctga tctagaccag cagctcatct   2340

gatagaggca gaggtggcct taaagatgtg gccttcttca ttttctgttg gtttggtttc   2400

gtttctatga gagatttcct ctgatagctc tgctttcccc agcacttact ctctgagctt   2460

ttaaatgttc tctctgggag cttcatataa gctcggtgac atttgagcca cagtttttag   2520

atcagcacct ggaatacatg acacattctt actgaggtca tccagcactg ccatggtggc   2580

tgcccagtct tctggccagt gtgccaggca catgtccctg tcacacaggt tccaagaaac   2640

acatacgcag ccatgcatag accaacagat ttaatattat attgcagttt tcagcgatgc   2700

agaatgcagc tgcaattgtg ttttaaggag aagccaaatg gggatggttg tccctgcaac   2760

atggtgccac tcctgggcca tgtgcagcct cagtggacac tcttccatag cgctgaggcc   2820

ctggccccgc ctccagttac cctgtactgc ccactgcctt acagttcagt gcgcaggcct   2880

tcaccttttc atcaccagcc tctctgctca gtgctctgga gttcttgacc ttgtccttta   2940

tcatgagatt tgctgaaatc actaatgaaa ataactccca aaagcaacaa acaaaaatat   3000

tagtttaact ggcactgtgg tatattaaaa ggcacaaggg cattgtggct taacactttt   3060

gctggatccc aagagacgca catgatgtta aaaagagatc tggcagcagt actaatacta   3120

catttcagtg taatcatctt ggggtggttt ggccaggatt tcccaattcc ttgatatctg   3180

gagtttcttc accattgtcc ggcatcctgc ggaggcttaa tatacaggcg taaggtcagc   3240

agcaatttgt ctaataagtg atgagatcag tagctgaagt ctctaagctg ggccattact   3300

aaataccata gccatgttga tctggaaatt tatccctcta gtgtcttacc tcacataagc   3360

catttgccca ctgtgcaata tagaaaggtg ttttcaaaag tatttggccg tagattttca   3420

catccatcat aaggttggca ttcaataagg aaaaagttct aactccagta ttaaattgta   3480

cataaatccc aaatgttctt aaagaacact cagggacatg tttgttgcct gggattggta   3540

atgaaaggtt ggtttttgaa acttgaaatt tcaccattgg tttttttcct atcatttctg   3600

catatccagc aaaaggaatc tcatgttgac tcctggcaga gttcagtggc ttcagtctgt   3660

ctatctgttc tgaggggaaa attgtgttct ggatccagta atcaatttgg caactttaat   3720

cgaggttttc aaaattccaa ggagggttaa taaagaatga taatcagttt tatttgctaa   3780

tagctaagac aaatttgtaa taaagtgttt tataatactt caaaagcatg tg           3832


<210>  6143
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  6143

Met Tyr Cys Thr Gly Gly Ile Arg Cys Glu Arg Gly Ser Ala Tyr Leu 
1               5                   10                  15


Lys Ala Lys Gly Val Cys Lys Glu Val Phe Gln Leu Lys Gly Gly Ile 
            20                  25                  30


His Lys Tyr Leu Glu Glu Phe Pro Asp Gly Phe Tyr Lys Gly Lys Leu 
        35                  40                  45


Phe Val Phe Asp Glu Arg Tyr Ala Leu Ser Tyr Asn Ser Asp Val Val 
    50                  55                  60


Ser Glu Cys Ser Tyr Cys Gly Ala Arg Trp Asp Gln Tyr Lys Leu Cys 
65                  70                  75                  80


Ser Thr Pro Gln Cys Arg Gln Leu Val Leu Thr Cys Pro Ala Cys Gln 
                85                  90                  95


Gly Gln Gly Phe Thr Ala Cys Cys Val Thr Cys Gln Asp Lys Gly Ser 
            100                 105                 110


Arg Lys Val Ser Gly Pro Met Gln Asp Ser Phe Lys Glu Glu Cys Glu 
        115                 120                 125


Cys Thr Ala Arg Arg Pro Arg Ile Pro Arg Glu Leu Leu Gln His Val 
    130                 135                 140


Arg Gln Pro Val Ser Pro Glu Pro Gly Pro Asp Ala Asp Glu Asp Gly 
145                 150                 155                 160


Pro Val Leu Met 



<210>  6144
<211>  6714
<212>  DNA
<213>  Homo sapiens

<400>  6144
ggaaaaagta ttcagcatta ctactaatca aaaatattaa aaaaaaaaat agggtagcat     60

ttcttttgcc ttttatttgg accaacatta aaaatattga tgataaaaaa tactgataga    120

actcagtgag gctatggata aaatggcacc cacatgcttt tctggttaga gtataaattg    180

gtacattttt cctggaagtc actattacag attaaaattt catgttcttt gacccctcaa    240

tttttatttt agatattcta agtaggtggt taaagatata gaaagataga tgcatggaat    300

gctcattcaa catggctttt aattgcaaat attagaaaca atctaaatgt tcatcagttg    360

gtaactggtt aagagaattt tctgtttgat tgttttacaa taagcataag taatttttat    420

aaaaacagta atattatttt ccaagaagga agatattttg gtacgtttct tcctggtctt    480

tttcaatgta ctttttaatg tggttaagat tacattgcat aagcaatttt atccaatttt    540

tttcacttaa tattatatca taaaatattt ttccatataa cttaaaactg gctgcttaat    600

attccatggt aagcatactt cataatttac tttccatatt cctttcgaaa ataactaata    660

gtgttatttg tgatatttta ggccaaactg tattatgtat tttccagtgt gacttagtct    720

tatatcctga gaataaaatt atgatgctga gagttattta acctcctcaa tataaagcct    780

agttttaatt tctctaatag tctcttctaa agcttactaa taagagaagt gttacttctc    840

agagaattgt ataacataat ggaacataaa actagaagcc cctgtggaaa gataatctaa    900

agaatcttag tgagacttct attagccata aacctaaggt tatttaacag tgttagcatt    960

tgaaatctaa ttgcaggcct ttgccctttt tgtcaaaacc aaagaagttc caacaaaaag   1020

gagttttgaa tgtaaagaaa aattgtggaa atgctgtcgg cagctattca cagaccaaac   1080

cagcatccat agacatgtgg caacacaaca tgctgatgaa atttatcacc agacagcttc   1140

tattttaaag caactggctg tgacattgag cacctcaaag agtctttcgt ctgcagatga   1200

aaagaaccct ttaaaagagt gccttccaca tagccatgac gtgtctgctt ggctccctga   1260

tataagctgc tttaaccctg atgagctgat aagtggccag ggcagtgaag aaggggaggt   1320

gctcctttat tactgctacc atgacctgga ggatccccaa tggatctgtg cctggcagac   1380

agctctgtgt cagcacctgc acctcacagg caagattcga attgctgcag aaggaatcaa   1440

tgggacagtt ggtggaagca aattggctac cagactttat gtggaagtca tgctttcctt   1500

cccattgttt aaggatgacc tgtgtaaaga tgattttaag accagcaaag gaggagctca   1560

ctgttttcca gaattgcgtg ttggtgtatt tgaagaaatc gtgcccatgg ggatcagccc   1620

caaaaagatc tcctacaaga agcctggaat ccatttatcc ccaggtgaat ttcataaaga   1680

agtagaaaag tttttatctc aggcaaatca agaacaaagt gatactatcc ttcttgattg   1740

cagaaacttc tatgaaagca aaataggacg attccaaggc tgcttagccc cagacatcag   1800

gaaattcagt tacttcccta gctacgttga caaaaatcta gaacttttca gagagaagag   1860

agtgctgatg tactgtaccg ggggcatccg ctgtgagcgg ggttcagcct acctcaaagc   1920

caagggagtg tgcaaggagg tgttccagct caagggtggc atccacaagt acctggaaga   1980

gtttcctgat ggcttttaca aagggaagtt gtttgttttt gatgaacgct atgctctgtc   2040

ctacaacagt gatgtggtgt caggtaggtc agcacaggct cagagcccaa actgaaatga   2100

agcacattgt cagttcacta ttctagaaaa atgacacagg gaagacaggc cagtgctcat   2160

tactgagcac tgaataagca gggaaaataa gtacattgtg ccaccatttt cccagctgtg   2220

gagctgagag aaccctagcc caggagtcag gaggcctggg ttgggatcct ggcttcacca   2280

ttgctagctg gacaagccca ttaacatggg gatcatctca cctgccctgc ctgcctgtct   2340

acctgccaag agctgtacta ctgggctaat tcagggctct taacctggaa ttggtacata   2400

gatttcaggg attctgtgaa tttggatgga aaaataattg tatctttgtt ttcaataaca   2460

cctcactaaa atgaagcatt tcctttagtt atgaatgtag gcaacaaagt accagttgta   2520

ttaatgtacc tgtgactttg tcttcagtag gattcacaat actttcatat catgttctag   2580

ttgcctcaga tatctcaaaa tagtatttat actcatcact gcttcaaaat gaaaatagtt   2640

attaggccca ccactaagag ttgatatata atgtgttaat aaatggcacg tcttattata   2700

tattacagat tttgaaaaag actttgatat tttgtatttc tgtatagttg gtttcctttg   2760

taatcttaca tattttatgc atttaaaaat atttttctag gtcaggcaca gaggctcatg   2820

cctgtaatcc catcactttt ggaggccaag gtaggaggat cacttgagcc ctggagtttg   2880

agaccagtct gggcaacata gctcactatg tctctacaaa aactttttta aattagctga   2940

gcatggtggt gtgtaccaga tactcaggag gctgaggcag gaggattgct tgagcccggg   3000

aggttgaggt tgcagtgagt ttaaatcatg ccactgtact ccagcctggg tgacacagca   3060

agaccctgtc tcaaaaaagt ttttctaggc caggatctat agtcttcacc agactaccaa   3120

gtaaatccgt agcacacatg attttaggaa ctcatagctc tctgtggacc caggtggcat   3180

gcacatttga gtaagatttg cgtttgattg tcctctccta ctttcttggt cttattttca   3240

ttttagtggt tttgagttgt ctcttattga tcactacttc gatctgtttt ggagctagat   3300

ggagtataaa ttctaaacaa gtagaaagag tagatttgat tttacagagg ttatattggc   3360

tggactcgat gggtacctgc gtgtgagtat gaaggagaga gggaaggctc agaggtagct   3420

tagataagca aggtaaggaa aagtgaggaa gaatgatgtt atcaatagta acaggaggtc   3480

atcagggaaa aacaggtgaa gaagatggtg tgagttttag gaatcagatg gtcaagtgcc   3540

ctagcaacag caggagagac acaggcctcg gggagagggg tgtggactgc gcatgttcac   3600

tgtaggtggg ttatcgcctg tatttaggtg tgttgtcccc cctggaaaag ggaacaatca   3660

aagaggaaaa gaccacttaa caagggggtt gggaggtagt tggccagctt tggaatagct   3720

ggtgagagag agaaactttc attaccatct agttaccacc tgttctctag atgggaaaaa   3780

gaaaaaaaaa gtcagtaaat actggaagca gacagttacc agaagtcacc cccacaaaaa   3840

aataagctgg gtggtggggg tggtggttag ttgttgttgc tagaagacag aagacttact   3900

atttggaaac cttccccggg ttccacagga tctacgagat tctagtcagc aaagggagca   3960

atgcctgtcc acgtgtgtgt gaatgtatgt gtttataatg atggcttttc cttcctcccc   4020

agagtgttca tactgtggag cccgctggga ccagtataaa ctctgctcta ctccccagtg   4080

ccgccagctc gttttgacct gccctgcctg tcaaggacaa ggattcacag cctgttgtgt   4140

cacatgtcaa gacaagggga gcaggaaagt ttcaggccct atgcaagaca gctttaaaga   4200

ggaatgcgag tgcacagccc gacggccacg catacctagg gaactcttgc agcatgtgcg   4260

acagcctgtg agcccagagc cagggcctga tgctgatgag gatgggccag tgcttatgtg   4320

agcagcacct ttggcatttt cccaggccct cggtaaaagt aggtttgggg tgactataca   4380

gagaaagcat ggcaagactg cagaaacaga gaaatcggga acttcagttc tggccgctgc   4440

caccgtggca gccgtctaca cttcacagcg ggaggggagg agtcacgttg tctaccactt   4500

acctgagaca ttctgatttg gatgatgcta gagcacagaa aataggtgag ctgcatggga   4560

tcccaaagct gctgagggat agagcctgag cctggtggcc acagcatatg ccctttctgt   4620

tccatgcagc tggggctgtt agtagtcatt gcccttgtca gcagaccttc taccctggtg   4680

gcaaacacat gaaagctgtg gccctgggag tggcctccta aaacaagcca cttaggtcat   4740

ctgccatcta cccttaacct ctgtctctcg cctgagggga atctgcaagc tgtgcattgg   4800

gcttacctcc tgcttttgta gaaataacca tcctttggta tacatggagg atagttccag   4860

aacgcctgag tatacaaaaa cccaatgcat actcaagtcc cacagtgggc cctacagaac   4920

ccacgtatgt gataaatcag ccctccatgt acgcaggttt cgccccctgc caatactgta   4980

ttttcaacct gtatggttga aaaaaatcca tatataagtg cagccatgca gttcaaaccc   5040

atattgttca agggtcaact gtatagttta ttgaacagcc acacccattc ctttacacat   5100

gatctatggc agagttgaat agttgcaaca gacactatgt ggcctgcaaa atcggaaatt   5160

tttactgtct ggccttttac agaaaagttt gccagcccct gatctagacc agcagctcat   5220

ctgatagagg cagaggtggc cttaaagatg tggccttctt cattttctgt tggtttggtt   5280

tcgtttctat gagagatttc ctctgatagc tctgctttcc ccagcactta ctctctgagc   5340

ttttaaatgt tctctctggg agcttcatat aagctcggtg acatttgagc cacagttttt   5400

agatcagcac ctggaataca tgacacattc ttactgaggt catccagcac tgccatggtg   5460

gctgcccagt cttctggcca gtgtgccagg cacatgtccc tgtcacacag gttccaagaa   5520

acacatacgc agccatgcat agaccaacag atttaatatt atattgcagt tttcagcgat   5580

gcagaatgca gctgcaattg tgttttaagg agaagccaaa tggggatggt tgtccctgca   5640

acatggtgcc actcctgggc catgtgcagc ctcagtggac actcttccat agcgctgagg   5700

ccctggcccc gcctccagtt accctgtact gcccactgcc ttacagttca gtgcgcaggc   5760

cttcaccttt tcatcaccag cctctctgct cagtgctctg gagttcttga ccttgtcctt   5820

tatcatgaga tttgctgaaa tcactaatga aaataactcc caaaagcaac aaacaaaaat   5880

attagtttaa ctggcactgt ggtatattaa aaggcacaag ggcattgtgg cttaacactt   5940

ttgctggatc ccaagagacg cacatgatgt taaaaagaga tctggcagca gtactaatac   6000

tacatttcag tgtaatcatc ttggggtggt ttggccagga tttcccaatt ccttgatatc   6060

tggagtttct tcaccattgt ccggcatcct gcggaggctt aatatacagg cgtaaggtca   6120

gcagcaattt gtctaataag tgatgagatc agtagctgaa gtctctaagc tgggccatta   6180

ctaaatacca tagccatgtt gatctggaaa tttatccctc tagtgtctta cctcacataa   6240

gccatttgcc cactgtgcaa tatagaaagg tgttttcaaa agtatttggc cgtagatttt   6300

cacatccatc ataaggttgg cattcaataa ggaaaaagtt ctaactccag tattaaattg   6360

tacataaatc ccaaatgttc ttaaagaaca ctcagggaca tgtttgttgc ctgggattgg   6420

taatgaaagg ttggtttttg aaacttgaaa tttcaccatt ggtttttttc ctatcatttc   6480

tgcatatcca gcaaaaggaa tctcatgttg actcctggca gagttcagtg gcttcagtct   6540

gtctatctgt tctgagggga aaattgtgtt ctggatccag taatcaattt ggcaacttta   6600

atcgaggttt tcaaaattcc aaggagggtt aataaagaat gataatcagt tttatttgct   6660

aatagctaag acaaatttgt aataaagtgt tttataatac ttcaaaagca tgtg         6714


<210>  6145
<211>  201
<212>  PRT
<213>  Homo sapiens

<400>  6145

Met Leu Ser Phe Pro Leu Phe Lys Asp Asp Leu Cys Lys Asp Asp Phe 
1               5                   10                  15


Lys Thr Ser Lys Gly Gly Ala His Cys Phe Pro Glu Leu Arg Val Gly 
            20                  25                  30


Val Phe Glu Glu Ile Val Pro Met Gly Ile Ser Pro Lys Lys Ile Ser 
        35                  40                  45


Tyr Lys Lys Pro Gly Ile His Leu Ser Pro Gly Glu Phe His Lys Glu 
    50                  55                  60


Val Glu Lys Phe Leu Ser Gln Ala Asn Gln Glu Gln Ser Asp Thr Ile 
65                  70                  75                  80


Leu Leu Asp Cys Arg Asn Phe Tyr Glu Ser Lys Ile Gly Arg Phe Gln 
                85                  90                  95


Gly Cys Leu Ala Pro Asp Ile Arg Lys Phe Ser Tyr Phe Pro Ser Tyr 
            100                 105                 110


Val Asp Lys Asn Leu Glu Leu Phe Arg Glu Lys Arg Val Leu Met Tyr 
        115                 120                 125


Cys Thr Gly Gly Ile Arg Cys Glu Arg Gly Ser Ala Tyr Leu Lys Ala 
    130                 135                 140


Lys Gly Val Cys Lys Glu Val Phe Gln Leu Lys Gly Gly Ile His Lys 
145                 150                 155                 160


Tyr Leu Glu Glu Phe Pro Asp Gly Phe Tyr Lys Gly Lys Leu Phe Val 
                165                 170                 175


Phe Asp Glu Arg Tyr Ala Leu Ser Tyr Asn Ser Asp Val Val Ser Gly 
            180                 185                 190


Arg Ser Ala Gln Ala Gln Ser Pro Asn 
        195                 200


<210>  6146
<211>  2636
<212>  DNA
<213>  Homo sapiens

<400>  6146
gagacttccg gagcttggtg acgtcacgag cgagcttttc tacccaaata cgcggcgggg     60

gaataggctc gagggcggtg agcagtgaca attgctaggc ggagacagtg cagggaagag    120

agaccttaga aaggatcagg actggcggga ggtatttaac tgaaaggaat atctgcttca    180

ctgttgcaac caaaccagat gccttcttcc acttcaccag accaaggaga tgacctggag    240

aactgcattt taagattttc tgacctggat ttaaaagata tgagtcttat taatcccagc    300

agcagtctta aagcagaatt agatggcagt acaaaaaaga aatactcgtt tgcaaagaaa    360

aaggtagaat tcttatgaat gtttcatgat catgtatgtg tggttaacgc agatacattt    420

ggaagtcggt tatcaaggtt gctctccagc tcaaggcctt tgcccttttt gtcaaaacca    480

aagaagttcc aacaaaaagg agttttgaat gtaaagaaaa attgtggaaa tgctgtcggc    540

agctattcac agaccaaacc agcatccata gacatgtggc aacacaacat gctgatgaaa    600

tttatcacca gacagcttct attttaaagc aactggctgt gacattgagc acctcaaaga    660

gtctttcgtc tgcagatgaa aagaaccctt taaaagagtg ccttccacat agccatgacg    720

tgtctgcttg gctccctgat ataagctgct ttaaccctga tgagctgata agtggccagg    780

gcagtgaaga aggggaggtg ctcctttatt actgctacca tgacctggag gatccccaat    840

ggatctgtgc ctggcagaca gctctgtgtc agcacctgca cctcacaggc aagattcgaa    900

ttgctgcaga aggaatcaat gggacagttg gtggaagcaa attggctacc agactttatg    960

tggaagtcat gctttccttc ccattgttta aggatgacct gtgtaaagat gattttaaga   1020

ccagcaaagg aggagctcac tgttttccag aattgcgtgt tggtgtattt gaagaaatcg   1080

tgcccatggg gatcagcccc aaaaagatct cctacaagaa gcctggaatc catttatccc   1140

caggtgaatt tcataaagaa gtagaaaagt ttttatctca ggcaaatcaa gaacaaagtg   1200

atactatcct tcttgattgc agaaacttct atgaaagcaa aataggacga ttccaaggct   1260

gcttagcccc agacatcagg aaattcagtt acttccctag ctacgttgac aaaaatctag   1320

aacttttcag agagaagaga gtgctgatgt actgtaccgg gggcatccgc tgtgagcggg   1380

gttcagccta cctcaaagcc aagggagtgt gcaaggaggt gttccagctc aagggtggca   1440

tccacaagta cctggaagag tttcctgatg gcttttacaa agggaagttg tttgtttttg   1500

atgaacgcta tgctctgtcc tacaacagtg atgtggtgtc agagtgttca tactgtggag   1560

cccgctggga ccagtataaa ctctgctcta ctccccatgg acactcttcc atagcgctga   1620

ggccctggcc ccgcctccag ttaccctgta ctgcccactg ccttacagtt cagtgcgcag   1680

gccttcacct tttcatcacc agcctctctg ctcagtgctc tggagttctt gaccttgtcc   1740

tttatcatga gatttgctga aatcactaat gaaaataact cccaaaagca acaaacaaaa   1800

atattagttt aactggcact gtggtatatt aaaaggcaca agggcattgt ggcttaacac   1860

ttttgctgga tcccaagaga cgcacatgat gttaaaaaga gatctggcag cagtactaat   1920

actacatttc agtgtaatca tcttggggtg gtttggccag gatttcccaa ttccttgata   1980

tctggagttt cttcaccatt gtccggcatc ctgcggaggc ttaatataca ggcgtaaggt   2040

cagcagcaat ttgtctaata agtgatgaga tcagtagctg aagtctctaa gctgggccat   2100

tactaaatac catagccatg ttgatctgga aatttatccc tctagtgtct tacctcacat   2160

aagccatttg cccactgtgc aatatagaaa ggtgttttca aaagtatttg gccgtagatt   2220

ttcacatcca tcataaggtt ggcattcaat aaggaaaaag ttctaactcc agtattaaat   2280

tgtacataaa tcccaaatgt tcttaaagaa cactcaggga catgtttgtt gcctgggatt   2340

ggtaatgaaa ggttggtttt tgaaacttga aatttcacca ttggtttttt tcctatcatt   2400

tctgcatatc cagcaaaagg aatctcatgt tgactcctgg cagagttcag tggcttcagt   2460

ctgtctatct gttctgaggg gaaaattgtg ttctggatcc agtaatcaat ttggcaactt   2520

taatcgaggt tttcaaaatt ccaaggaggg ttaataaaga atgataatca gttttatttg   2580

ctaatagcta agacaaattt gtaataaagt gttttataat acttcaaaag catgtg       2636


<210>  6147
<211>  263
<212>  PRT
<213>  Homo sapiens

<400>  6147

Met Leu Ser Phe Pro Leu Phe Lys Asp Asp Leu Cys Lys Asp Asp Phe 
1               5                   10                  15


Lys Thr Ser Lys Gly Gly Ala His Cys Phe Pro Glu Leu Arg Val Gly 
            20                  25                  30


Val Phe Glu Glu Ile Val Pro Met Gly Ile Ser Pro Lys Lys Ile Ser 
        35                  40                  45


Tyr Lys Lys Pro Gly Ile His Leu Ser Pro Gly Glu Phe His Lys Glu 
    50                  55                  60


Val Glu Lys Phe Leu Ser Gln Ala Asn Gln Glu Gln Ser Asp Thr Ile 
65                  70                  75                  80


Leu Leu Asp Cys Arg Asn Phe Tyr Glu Ser Lys Ile Gly Arg Phe Gln 
                85                  90                  95


Gly Cys Leu Ala Pro Asp Ile Arg Lys Phe Ser Tyr Phe Pro Ser Tyr 
            100                 105                 110


Val Asp Lys Asn Leu Glu Leu Phe Arg Glu Lys Arg Val Leu Met Tyr 
        115                 120                 125


Cys Thr Gly Gly Ile Arg Cys Glu Arg Gly Ser Ala Tyr Leu Lys Ala 
    130                 135                 140


Lys Gly Val Cys Lys Glu Val Phe Gln Leu Lys Gly Gly Ile His Lys 
145                 150                 155                 160


Tyr Leu Glu Glu Phe Pro Asp Gly Phe Tyr Lys Gly Lys Leu Phe Val 
                165                 170                 175


Phe Asp Glu Arg Tyr Ala Leu Ser Tyr Asn Ser Asp Val Val Ser Glu 
            180                 185                 190


Cys Ser Tyr Cys Gly Ala Arg Trp Asp Gln Tyr Lys Leu Cys Ser Thr 
        195                 200                 205


Pro His Gly His Ser Ser Ile Ala Leu Arg Pro Trp Pro Arg Leu Gln 
    210                 215                 220


Leu Pro Cys Thr Ala His Cys Leu Thr Val Gln Cys Ala Gly Leu His 
225                 230                 235                 240


Leu Phe Ile Thr Ser Leu Ser Ala Gln Cys Ser Gly Val Leu Asp Leu 
                245                 250                 255


Val Leu Tyr His Glu Ile Cys 
            260


<210>  6148
<211>  4249
<212>  DNA
<213>  Homo sapiens

<400>  6148
cggccgctct agtctccgcc tccgctcagg ccggtcctcc ggggcttctc aatggtttcc     60

cggtggcctc tcaatggttt tcccggcggc ccttgcgccg acgccaggag acttccggag    120

cttggtgacg tcacgagcga gcttttctac ccaaatacgc ggcgggggaa taggctcgag    180

ggcggtgagc agtgacaatt gctaggcgga gacagtgcag ggaagagaga ccttagaaag    240

gatcaggact ggcgggaggt atttaactga aaggaatatc tgcttcactg ttgcaaccaa    300

accagatgcc ttcttccact tcaccagacc aaggagatga cctggagaac tgcattttaa    360

gattttctga cctggattta aaagatatga gtcttattaa tcccagcagc agtcttaaag    420

cagaattaga tggcagtaca aaaaagaaat actcgtttgc aaagaaaaag gcctttgccc    480

tttttgtcaa aaccaaagaa gttccaacaa aaaggagttt tgaatgtaaa gaaaaattgt    540

ggaaatgctg tcggcagcta ttcacagacc aaaccagcat ccatagacat gtggcaacac    600

aacatgctga tgaaatttat caccagacag cttctatttt aaagcaactg gctgtgacat    660

tgagcacctc aaagagtctt tcgtctgcag atgaaaagaa ccctttaaaa gagtgccttc    720

cacatagcca tgacgtgtct gcttggctcc ctgatataag ctgctttaac cctgatgagc    780

tgataagtgg ccagggcagt gaagaagggg aggtgctcct ttattactgc taccatgacc    840

tggaggatcc ccaatggatc tgtgcctggc agacagctct gtgtcagcac ctgcacctca    900

caggcaagat tcgaattgct gcagaaggaa tcaatgggac agttggtgga agcaaattgg    960

ctaccagact ttatgtggaa gtcatgcttt ccttcccatt gtttaaggat gacctgtgta   1020

aagatgattt taagaccagc aaaggaggag ctcactgttt tccagaattg cgtgttggtg   1080

tatttgaaga aatcgtgccc atggggatca gccccaaaaa gatctcctac aagaagcctg   1140

gaatccattt atccccaggt gaatttcata aagaagtaga aaagttttta tctcaggcaa   1200

atcaagaaca aagtgatact atccttcttg attgcagaaa cttctatgaa agcaaaatag   1260

gacgattcca aggctgctta gccccagaca tcaggaaatt cagttacttc cctagctacg   1320

ttgacaaaaa tctagaactt ttcagagaga agagagtgct gatgtactgt accgggggca   1380

tccgctgtga gcggggttca gcctacctca aagccaaggg agtgtgcaag gaggtgttcc   1440

agctcaaggg tggcatccac aagtacctgg aagagtttcc tgatggcttt tacaaaggga   1500

agttgtttgt ttttgatgaa cgctatgctc tgtcctacaa cagtgatgtg gtgtcagagt   1560

gttcatactg tggagcccgc tgggaccagt ataaactctg ctctactccc cagtgccgcc   1620

agctcgtttt gacctgccct gcctgtcaag gacaaggatt cacagcctgt tgtgtcacat   1680

gtcaagacaa ggggagcagg aaagtttcag gccctatgca agacagcttt aaagaggaat   1740

gcgagtgcac agcccgacgg ccacgcatac ctagggaact cttgcagcat gtgcgacagc   1800

ctgtgagccc agagccaggg cctgatgctg atgaggatgg gccagtgctt atgtgagcag   1860

cacctttggc attttcccag gccctcggta aaagtaggtt tggggtgact atacagagaa   1920

agcatggcaa gactgcagaa acagagaaat cgggaacttc agttctggcc gctgccaccg   1980

tggcagccgt ctacacttca cagcgggagg ggaggagtca cgttgtctac cacttacctg   2040

agacattctg atttggatga tgctagagca cagaaaatag gtgagctgca tgggatccca   2100

aagctgctga gggatagagc ctgagcctgg tggccacagc atatgccctt tctgttccat   2160

gcagctgggg ctgttagtag tcattgccct tgtcagcaga ccttctaccc tggtggcaaa   2220

cacatgaaag ctgtggccct gggagtggcc tcctaaaaca agccacttag gtcatctgcc   2280

atctaccctt aacctctgtc tctcgcctga ggggaatctg caagctgtgc attgggctta   2340

cctcctgctt ttgtagaaat aaccatcctt tggtatacat ggaggatagt tccagaacgc   2400

ctgagtatac aaaaacccaa tgcatactca agtcccacag tgggccctac agaacccacg   2460

tatgtgataa atcagccctc catgtacgca ggtttcgccc cctgccaata ctgtattttc   2520

aacctgtatg gttgaaaaaa atccatatat aagtgcagcc atgcagttca aacccatatt   2580

gttcaagggt caactgtata gtttattgaa cagccacacc cattccttta cacatgatct   2640

atggcagagt tgaatagttg caacagacac tatgtggcct gcaaaatcgg aaatttttac   2700

tgtctggcct tttacagaaa agtttgccag cccctgatct agaccagcag ctcatctgat   2760

agaggcagag gtggccttaa agatgtggcc ttcttcattt tctgttggtt tggtttcgtt   2820

tctatgagag atttcctctg atagctctgc tttccccagc acttactctc tgagctttta   2880

aatgttctct ctgggagctt catataagct cggtgacatt tgagccacag tttttagatc   2940

agcacctgga atacatgaca cattcttact gaggtcatcc agcactgcca tggtggctgc   3000

ccagtcttct ggccagtgtg ccaggcacat gtccctgtca cacaggttcc aagaaacaca   3060

tacgcagcca tgcatagacc aacagattta atattatatt gcagttttca gcgatgcaga   3120

atgcagctgc aattgtgttt taaggagaag ccaaatgggg atggttgtcc ctgcaacatg   3180

gtgccactcc tgggccatgt gcagcctcag tggacactct tccatagcgc tgaggccctg   3240

gccccgcctc cagttaccct gtactgccca ctgccttaca gttcagtgcg caggccttca   3300

ccttttcatc accagcctct ctgctcagtg ctctggagtt cttgaccttg tcctttatca   3360

tgagatttgc tgaaatcact aatgaaaata actcccaaaa gcaacaaaca aaaatattag   3420

tttaactggc actgtggtat attaaaaggc acaagggcat tgtggcttaa cacttttgct   3480

ggatcccaag agacgcacat gatgttaaaa agagatctgg cagcagtact aatactacat   3540

ttcagtgtaa tcatcttggg gtggtttggc caggatttcc caattccttg atatctggag   3600

tttcttcacc attgtccggc atcctgcgga ggcttaatat acaggcgtaa ggtcagcagc   3660

aatttgtcta ataagtgatg agatcagtag ctgaagtctc taagctgggc cattactaaa   3720

taccatagcc atgttgatct ggaaatttat ccctctagtg tcttacctca cataagccat   3780

ttgcccactg tgcaatatag aaaggtgttt tcaaaagtat ttggccgtag attttcacat   3840

ccatcataag gttggcattc aataaggaaa aagttctaac tccagtatta aattgtacat   3900

aaatcccaaa tgttcttaaa gaacactcag ggacatgttt gttgcctggg attggtaatg   3960

aaaggttggt ttttgaaact tgaaatttca ccattggttt ttttcctatc atttctgcat   4020

atccagcaaa aggaatctca tgttgactcc tggcagagtt cagtggcttc agtctgtcta   4080

tctgttctga ggggaaaatt gtgttctgga tccagtaatc aatttggcaa ctttaatcga   4140

ggttttcaaa attccaagga gggttaataa agaatgataa tcagttttat ttgctaatag   4200

ctaagacaaa tttgtaataa agtgttttat aatacttcaa aagcatgtg               4249


<210>  6149
<211>  516
<212>  PRT
<213>  Homo sapiens

<400>  6149

Met Pro Ser Ser Thr Ser Pro Asp Gln Gly Asp Asp Leu Glu Asn Cys 
1               5                   10                  15


Ile Leu Arg Phe Ser Asp Leu Asp Leu Lys Asp Met Ser Leu Ile Asn 
            20                  25                  30


Pro Ser Ser Ser Leu Lys Ala Glu Leu Asp Gly Ser Thr Lys Lys Lys 
        35                  40                  45


Tyr Ser Phe Ala Lys Lys Lys Ala Phe Ala Leu Phe Val Lys Thr Lys 
    50                  55                  60


Glu Val Pro Thr Lys Arg Ser Phe Glu Cys Lys Glu Lys Leu Trp Lys 
65                  70                  75                  80


Cys Cys Arg Gln Leu Phe Thr Asp Gln Thr Ser Ile His Arg His Val 
                85                  90                  95


Ala Thr Gln His Ala Asp Glu Ile Tyr His Gln Thr Ala Ser Ile Leu 
            100                 105                 110


Lys Gln Leu Ala Val Thr Leu Ser Thr Ser Lys Ser Leu Ser Ser Ala 
        115                 120                 125


Asp Glu Lys Asn Pro Leu Lys Glu Cys Leu Pro His Ser His Asp Val 
    130                 135                 140


Ser Ala Trp Leu Pro Asp Ile Ser Cys Phe Asn Pro Asp Glu Leu Ile 
145                 150                 155                 160


Ser Gly Gln Gly Ser Glu Glu Gly Glu Val Leu Leu Tyr Tyr Cys Tyr 
                165                 170                 175


His Asp Leu Glu Asp Pro Gln Trp Ile Cys Ala Trp Gln Thr Ala Leu 
            180                 185                 190


Cys Gln His Leu His Leu Thr Gly Lys Ile Arg Ile Ala Ala Glu Gly 
        195                 200                 205


Ile Asn Gly Thr Val Gly Gly Ser Lys Leu Ala Thr Arg Leu Tyr Val 
    210                 215                 220


Glu Val Met Leu Ser Phe Pro Leu Phe Lys Asp Asp Leu Cys Lys Asp 
225                 230                 235                 240


Asp Phe Lys Thr Ser Lys Gly Gly Ala His Cys Phe Pro Glu Leu Arg 
                245                 250                 255


Val Gly Val Phe Glu Glu Ile Val Pro Met Gly Ile Ser Pro Lys Lys 
            260                 265                 270


Ile Ser Tyr Lys Lys Pro Gly Ile His Leu Ser Pro Gly Glu Phe His 
        275                 280                 285


Lys Glu Val Glu Lys Phe Leu Ser Gln Ala Asn Gln Glu Gln Ser Asp 
    290                 295                 300


Thr Ile Leu Leu Asp Cys Arg Asn Phe Tyr Glu Ser Lys Ile Gly Arg 
305                 310                 315                 320


Phe Gln Gly Cys Leu Ala Pro Asp Ile Arg Lys Phe Ser Tyr Phe Pro 
                325                 330                 335


Ser Tyr Val Asp Lys Asn Leu Glu Leu Phe Arg Glu Lys Arg Val Leu 
            340                 345                 350


Met Tyr Cys Thr Gly Gly Ile Arg Cys Glu Arg Gly Ser Ala Tyr Leu 
        355                 360                 365


Lys Ala Lys Gly Val Cys Lys Glu Val Phe Gln Leu Lys Gly Gly Ile 
    370                 375                 380


His Lys Tyr Leu Glu Glu Phe Pro Asp Gly Phe Tyr Lys Gly Lys Leu 
385                 390                 395                 400


Phe Val Phe Asp Glu Arg Tyr Ala Leu Ser Tyr Asn Ser Asp Val Val 
                405                 410                 415


Ser Glu Cys Ser Tyr Cys Gly Ala Arg Trp Asp Gln Tyr Lys Leu Cys 
            420                 425                 430


Ser Thr Pro Gln Cys Arg Gln Leu Val Leu Thr Cys Pro Ala Cys Gln 
        435                 440                 445


Gly Gln Gly Phe Thr Ala Cys Cys Val Thr Cys Gln Asp Lys Gly Ser 
    450                 455                 460


Arg Lys Val Ser Gly Pro Met Gln Asp Ser Phe Lys Glu Glu Cys Glu 
465                 470                 475                 480


Cys Thr Ala Arg Arg Pro Arg Ile Pro Arg Glu Leu Leu Gln His Val 
                485                 490                 495


Arg Gln Pro Val Ser Pro Glu Pro Gly Pro Asp Ala Asp Glu Asp Gly 
            500                 505                 510


Pro Val Leu Met 
        515


<210>  6150
<211>  1123
<212>  DNA
<213>  Homo sapiens

<400>  6150
tcccccctgg aaaagggaac aatcaaagag gaaaagacca cttaacaagg gggttgggag     60

gtagttggcc agctttggaa tagctggtga gagagagaaa ctttcattac catctagtta    120

ccacctgttc tctagatggg aaaaagaaaa aaaaagtcag taaatactgg aagcagacag    180

ttaccagaag tcacccccac aaaaaaataa gctgggtggt gggggtggtg gttagttgtt    240

gttgctagaa gacagaagac ttactatttg gaaaccttcc ccgggttcca caggatctac    300

gagattctag tcagcaaagg gagcaatgcc tgtccacgtg tgtgtgaatg tatgtgttta    360

taatgatggc ttttccttcc tccccagagt gttcatactg tggagcccgc tgggaccagt    420

ataaactctg ctctactccc cagtgccgcc agctcgtttt gacctgccct gcctgtcaag    480

gacaaggatt cacagcctgt tgtgtcacat gtcaagacaa ggggagcagg aaagtttcag    540

gccctatgca agacagcttt aaagaggaat gcgagtgcac agcccgacgg ccacgcatac    600

ctagggaact cttgcagcat gtgcgacagc ctgtgagccc agagccaggg cctgatgctg    660

atgaggatgg gccagtgctt atgtgagcag cacctttggc attttcccag gccctcggta    720

aaagtaggtt tggggtgact atacagagaa agcatggcaa gactgcagaa acagagaaat    780

cgggaacttc agttctggcc gctgccaccg tggcagccgt ctacacttca cagcgggagg    840

ggaggagtca cgttgtctac cacttacctg agacattctg atttggatga tgctagagca    900

cagaaaatag caaaaggaat ctcatgttga ctcctggcag agttcagtgg cttcagtctg    960

tctatctgtt ctgaggggaa aattgtgttc tggatccagt aatcaatttg gcaactttaa   1020

tcgaggtttt caaaattcca aggagggtta ataaagaatg ataatcagtt ttatttgcta   1080

atagctaaga caaatttgta ataaagtgtt ttataatact tca                     1123


<210>  6151
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  6151

Met Ala Arg Leu Gln Lys Gln Arg Asn Arg Glu Leu Gln Phe Trp Pro 
1               5                   10                  15


Leu Pro Pro Trp Gln Pro Ser Thr Leu His Ser Gly Arg Gly Gly Val 
            20                  25                  30


Thr Leu Ser Thr Thr Tyr Leu Arg His Ser Asp Leu Asp Asp Ala Arg 
        35                  40                  45


Ala Gln Lys Ile Ala Lys Gly Ile Ser Cys 
    50                  55


<210>  6152
<211>  987
<212>  DNA
<213>  Homo sapiens

<400>  6152
ctatgttccc caggcttccc cttgtatttt aatacttacc catcttctag ctttcctgtc     60

tttttctctc ctttactttc tttctcatat gtcgtttctg ttgtccaccc ctcttgccct    120

tttctctttt actcatgcac acacacttag acacattctt cttgctcctt tgcattaaaa    180

atgtatctat tccaacttta ttccataact ttttgctcac acctgcctgt gggttcttag    240

ccttcaacgt gggttcgacc ttaatataga acagtttaca aagcctgtag tcagccacgt    300

acttgcccag ctcctccatg tacagtgaca atagagcagt ggccatttcc tgacctacca    360

gtgaccatac aatggaccag caaattcaca tggcaattta gatcccagtt gcctggtttt    420

tatcactagg gttaggccaa gtatgaggat gcaaaattct ttgactagtt atttctaaac    480

taccaggtct ccattgccct cattttagga ggagggagat tgaggatacc tggaattact    540

ggaattacta agttatttca tcatgatcat caagtagtgt tcttttcaga cagttgtaat    600

tatgaagaga agagatttgg gtggaaagaa acaaagcaac acgaatccat ttatccccag    660

gtgaatttca taaagaagta gaaaagtttt tatctcaggc aaatcaagaa caaagtgata    720

ctatccttct tgattgcaga aacttctatg aaagcaaaat aggacgattc caaggctgct    780

tagccccaga catcaggaaa ttcagttact tccctagcta cgttgacaaa aatctagaac    840

ttttcagaga gaagagagtg ctgatgtact gtaccggggg catccgctgt gagcggggtt    900

cagcctacct caaagccaag gaggcaagat ctggccagtt ggtgccttga ccccttggtc    960

agcaattcct cagtgtcccg cagtggg                                        987


<210>  6153
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  6153

Met His Thr His Leu Asp Thr Phe Phe Leu Leu Leu Cys Ile Lys Asn 
1               5                   10                  15


Val Ser Ile Pro Thr Leu Phe His Asn Phe Leu Leu Thr Pro Ala Cys 
            20                  25                  30


Gly Phe Leu Ala Phe Asn Val Gly Ser Thr Leu Ile 
        35                  40


<210>  6154
<211>  1209
<212>  DNA
<213>  Homo sapiens

<400>  6154
agcctcggct cccaaccggg agcggcctcc gtggccgggc cgcaggcact caccgtcgtt     60

ctcgtcgctg tgccgccgcc gcgacatgct gccctccggt gcgccgcgga accgagaggc    120

caggcggtaa gcgctgcagg aactgtctgg ccgctggccg acgcaaggac agctgcaagg    180

cgcgcggatg ggccggcacg caggcgcact agctcgccac ggccccggaa gcgcaggaga    240

ggccgccggg tggggctagg cgctgcgaca gccggcgtga ggaagctcag tgggctacga    300

acgtctggca cacatgcaac cgccccctcg ggctgcctcc gcctgccggc tacttctttc    360

tcccgccttc cgctctatgt ccttccgggg ccacgcagaa agtgccgccg ctttggccac    420

tcagagcccc cgggccgcgg tcgtcgtacg cctgaaggcg ggtcgtgccg gcggccgctc    480

tagtctccgc ctccgctcag gccggtcctc cggggcttct caatggtttc ccggtggcct    540

ctcaatggtt ttcccggcgg cccttgcgcc gacgccagga gacttccgga gcttggtgac    600

gtcacgagcg agcttttcta cccaaatacg cggcggggga ataggctcga gggcggtgag    660

cagtgacaat tgctaggcgg agacagtgca gggaagagag accttagaaa ggatcaggac    720

tggcgggagg tatttaactg aaaggaatat ctgcttcact gttgcaacca aaccagatgc    780

cttcttccac ttcaccagac caaggagatg acctggagaa ctgcatttta agattttctg    840

acctggattt aaaagatatg agtcttatta atcccagcag cagtcttaaa gcagaattag    900

atggcagtac aaaaaagaaa tactcgtttg caaagaaaaa ggcctttgcc ctttttgtca    960

aaaccaaaga agttccaaca aaaaggagtt ttgaatgtaa agaaaaattg tggaaatgct   1020

gtcggcagct attcacagac caaaccagca tccatagaca tgtggcaaca caacatgctg   1080

atgaaattta tcaccagaca gctagattcg aattgctgca gaaggaatca atgggacagt   1140

tggtggaagc aaattggcta ccagacttta tgtggaagtc atgctttcct tcccattgtt   1200

taaggatga                                                           1209


<210>  6155
<211>  143
<212>  PRT
<213>  Homo sapiens

<400>  6155

Met Pro Ser Ser Thr Ser Pro Asp Gln Gly Asp Asp Leu Glu Asn Cys 
1               5                   10                  15


Ile Leu Arg Phe Ser Asp Leu Asp Leu Lys Asp Met Ser Leu Ile Asn 
            20                  25                  30


Pro Ser Ser Ser Leu Lys Ala Glu Leu Asp Gly Ser Thr Lys Lys Lys 
        35                  40                  45


Tyr Ser Phe Ala Lys Lys Lys Ala Phe Ala Leu Phe Val Lys Thr Lys 
    50                  55                  60


Glu Val Pro Thr Lys Arg Ser Phe Glu Cys Lys Glu Lys Leu Trp Lys 
65                  70                  75                  80


Cys Cys Arg Gln Leu Phe Thr Asp Gln Thr Ser Ile His Arg His Val 
                85                  90                  95


Ala Thr Gln His Ala Asp Glu Ile Tyr His Gln Thr Ala Arg Phe Glu 
            100                 105                 110


Leu Leu Gln Lys Glu Ser Met Gly Gln Leu Val Glu Ala Asn Trp Leu 
        115                 120                 125


Pro Asp Phe Met Trp Lys Ser Cys Phe Pro Ser His Cys Leu Arg 
    130                 135                 140


<210>  6156
<211>  647
<212>  DNA
<213>  Homo sapiens

<400>  6156
attgatgata aaaaatactg atagaactca gtgaggctat ggataaaatg gcacccacat     60

gcttttctgg ttagagtata aattggtaca tttttcctgg aagtcactat tacagattaa    120

aatttcatgt tctttgaccc ctcaattttt attttagata ttctaagtag gtggttaaag    180

atatagaaag atagatgcat ggaatgctca ttcaacatgg cttttaattg caaatattag    240

aaacaatcta aatgttcatc agttggtaac tggttaagag aattttctgt ttgattgttt    300

tacaataagc ataagtaatt tttataaaaa cagtaatatt attttccaag aaggaagata    360

ttttggtacg tttcttcctg gtctttttca atgtactttt taatgtggtt aagattacat    420

tgcataagca attttatcca atttttttca cttaatatta tatcataaaa tatttttcca    480

tataacttaa aactggctgc ttaatattcc atggcctttg ccctttttgt caaaaccaaa    540

gaagttccaa caaaaaggag ttttgaatgt aaagaaaaat tgtggaaatg ctgtcggcag    600

ctattcacag accaaaccag catccataga catgtggcaa cacaaca                  647


<210>  6157
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  6157

Met Ala Phe Ala Leu Phe Val Lys Thr Lys Glu Val Pro Thr Lys Arg 
1               5                   10                  15


Ser Phe Glu Cys Lys Glu Lys Leu Trp Lys Cys Cys Arg Gln Leu Phe 
            20                  25                  30


Thr Asp Gln Thr Ser Ile His Arg His Val Ala Thr 
        35                  40


<210>  6158
<211>  1314
<212>  DNA
<213>  Homo sapiens

<400>  6158
ggcaaaagcc ggaaagtggg agtagatgag cacatacccg ccagtcctga tcctttctaa     60

ggtctctctt ccctgcactg tctccgccta gcaattgtca ctgctcaccg ccctcgagcc    120

tattcccccg ccgcgtattt gggtagaaaa gctcgctcgt gacgtcacca agctccggaa    180

gtctcctggc gtcggcgcaa gggccgccgg gaaaaccatt gagaggccac cgggaaacca    240

ttgagaagcc ccggaggacc ggcctgagcg gaggcggaga ctagagcggc cgccggcacg    300

acccgccttc aggcgtacga cgaccgcggc ccgggggctc tgagtggcca aagcggcggc    360

actttctgcg tggccccgga aggacataga gcggaaggcg ggagaaagaa gtagccggca    420

ggcggaggca gcccgagggg gcggttgcat gtgtgccaga cgttcgtagc ccactgagct    480

tcctcacgcc ggctgtcgca gcgcctagcc ccacccggcg gcctctcctg cgcttccggg    540

gccgtggcga gctagtgcgc ctgcgtgccg gcccatccgc gcgccttgca gctgtccttg    600

cgtcggccag cggccagaca gttcctgcag cgcttaccgc ctggcctctc ggttccgcgg    660

cgcaccggag ggcagcatgt cgcggcggcg gcacagcgac gagaacgacg gtgggcagcc    720

tcacaaaagg agaaagacct ctgatgcaaa tgaaactgaa gatcatttgg aatctttaat    780

atgtaaagta ggagaaaaga gtgcctgctc tttggagagc aacctagaag gcttggctgg    840

tgttttggaa gctgatcttc ctaactacaa gagcaagatc ttaaggcttc tttgtacagt    900

gtatgtatgc aaaagattta tgaatccagg tgataatgta ttatctactc ttaaatgctt    960

tgggaaatgt tcaaaataca tgtttatgtt ctatatgtcc ttggctttac ttctatgggg   1020

aaatttgtac aaatgagcca acctttggcg ctttggcgaa ctctttttct tagggataaa   1080

actaaaattg aacattttcc ttgtatgttc ttacaacctt agaatcattt tagttgactt   1140

tttatagaga tagtagatac tgtctcattc agatatatat ttttaagcat gtacatttaa   1200

atgtatgata cttacatttt taaattagta ccagacaaat ttgggaattg gtaactcagg   1260

taatagccct tcttggaaga ctgaagatgc tttggaagcc actgttaata ggca         1314


<210>  6159
<211>  119
<212>  PRT
<213>  Homo sapiens

<400>  6159

Met Ser Arg Arg Arg His Ser Asp Glu Asn Asp Gly Gly Gln Pro His 
1               5                   10                  15


Lys Arg Arg Lys Thr Ser Asp Ala Asn Glu Thr Glu Asp His Leu Glu 
            20                  25                  30


Ser Leu Ile Cys Lys Val Gly Glu Lys Ser Ala Cys Ser Leu Glu Ser 
        35                  40                  45


Asn Leu Glu Gly Leu Ala Gly Val Leu Glu Ala Asp Leu Pro Asn Tyr 
    50                  55                  60


Lys Ser Lys Ile Leu Arg Leu Leu Cys Thr Val Tyr Val Cys Lys Arg 
65                  70                  75                  80


Phe Met Asn Pro Gly Asp Asn Val Leu Ser Thr Leu Lys Cys Phe Gly 
                85                  90                  95


Lys Cys Ser Lys Tyr Met Phe Met Phe Tyr Met Ser Leu Ala Leu Leu 
            100                 105                 110


Leu Trp Gly Asn Leu Tyr Lys 
        115


<210>  6160
<211>  3479
<212>  DNA
<213>  Homo sapiens

<400>  6160
ggcaaaagcc ggaaagtggg agtagatgag cacatacccg ccagtcctga tcctttctaa     60

ggtctctctt ccctgcactg tctccgccta gcaattgtca ctgctcaccg ccctcgagcc    120

tattcccccg ccgcgtattt gggtagaaaa gctcgctcgt gacgtcacca agctccggaa    180

gtctcctggc gtcggcgcaa gggccgccgg gaaaaccatt gagaggccac cgggaaacca    240

ttgagaagcc ccggaggacc ggcctgagcg gaggcggaga ctagagcggc cgccggcacg    300

acccgccttc aggcgtacga cgaccgcggc ccgggggctc tgagtggcca aagcggcggc    360

actttctgcg tggccccgga aggacataga gcggaaggcg ggagaaagaa gtagccggca    420

ggcggaggca gcccgagggg gcggttgcat gtgtgccaga cgttcgtagc ccactgagct    480

tcctcacgcc ggctgtcgca gcgcctagcc ccacccggcg gcctctcctg cgcttccggg    540

gccgtggcga gctagtgcgc ctgcgtgccg gcccatccgc gcgccttgca gctgtccttg    600

cgtcggccag cggccagaca gttcctgcag cgcttaccgc ctggcctctc ggttccgcgg    660

cgcaccggag ggcagcatgt cgcggcggcg gcacagcgac gagaacgacg gtgggcagcc    720

tcacaaaagg agaaagacct ctgatgcaaa tgaaactgaa gatcatttgg aatctttaat    780

atgtaaagta ggagaaaaga gtgcctgctc tttggagagc aacctagaag gcttggctgg    840

tgttttggaa gctgatcttc ctaactacaa gagcaagatc ttaaggcttc tttgtacagt    900

tgcacgccta ttacctgaga agctgacaat ttatacaaca ttagttggac tactgaatgc    960

caggaattac aattttggtg gagaatttgt agaagccatg attcgtcaac ttaaagaatc   1020

attgaaagca aacaattata atgaagccgt gtatttggtc cgttttttat ctgatcttgt   1080

gaattgtcat gtgattgccg ccccatcaat ggttgctatg tttgaaaatt ttgtaagcgt   1140

aactcaggaa gaagatgtac ctcaggtgcg acgagattgg tatgtgtatg catttctgtc   1200

atctttgccc tgggttggaa aggagttgta cgaaaagaaa gatgcagaga tggaccgcat   1260

ctttgccaac actgaaagct atcttaaaag acgccaaaag actcatgtac ccatgttaca   1320

ggtatggact gctgataaac cacatccaca agaagagtat ttagattgcc tgtgggccca   1380

gattcagaaa ttgaaaaagg atcgctggca ggaacggcac atcctaagac cttatcttgc   1440

ctttgacagc atcctgtgtg aagcactgca gcacaatctg cctcctttta caccacctcc   1500

tcacactgaa gattcagtgt acccaatgcc aagggtcatc ttcagaatgt ttgattacac   1560

agatgatccc gagggtcctg tcatgccagg gagtcattca gtggaaagat ttgtaataga   1620

agagaatctt cactgcatca ttaagtccca ctggaaggaa aggaagactt gtgctgcaca   1680

gttagtgagc tatccaggga agaacaagat ccccttgaac taccacatag ttgaggtgat   1740

ctttgcagag ctgtttcaac ttccagcacc ccctcacatt gatgtgatgt acacaacact   1800

cctcattgaa ctgtgcaaac ttcaacctgg ctctctaccc caagttcttg cacaggcaac   1860

tgaaatgcta tacatgcgtt tggacacaat gaacactacc tgtgtagaca ggtttattaa   1920

ttggttttct catcatctaa gtaacttcca gttccgttgg agctgggaag attggtcaga   1980

ttgtcttagt caagatcctg aaagtcccaa accgaagttt gtaagagaag ttctagaaaa   2040

atgtatgagg ttgtcttacc atcagcgtat attagatatt gttcctccta ccttctcagc   2100

tctgtgtcct gcaaacccaa cctgcattta caagtatgga gatgaaagta gcaattctct   2160

tcctggacat tctgttgccc tctgtttagc tgttgccttt aaaagtaagg caaccaatga   2220

tgaaatcttc agcattctga aagatgtacc aaatcctaac caggatgatg acgacgatga   2280

aggattcagt tttaacccat tgaaaataga agtctttgta cagactctgc tacacttggc   2340

agccaaatca ttcagccact ccttcagtgc tcttgcaaag tttcatgaag tcttcaaaac   2400

cctagctgaa agtgatgaag gaaagttaca tgtgctaaga gttatgtttg aggtctggag   2460

gaaccatcca cagatgattg ctgtactagt ggataagatg attcgtacac aaatagttga   2520

ttgtgctgcc gtagcaaatt ggatcttctc ttcagaacta tctcgtgact ttaccagatt   2580

gtttgtttgg gaaattttgc actctacaat tcgtaagatg aacaaacatg tcctgaagat   2640

ccagaaagag ctggaagaag ctaaagagaa acttgctagg caacacaaac ggcgaagtga   2700

tgatgacgac agaagcagtg acaggaaaga cggggttctt gaggaacaaa tagaacgact   2760

tcaggaaaaa gtggaatctg ctcagagtga acaaaagaat cttttcctcg ttatatttca   2820

gcggtttatc atgatcttga ccgagcacct agtacgatgc gaaactgatg ggaccagtgt   2880

attaacacca tggtataaga actgtataga gaggctgcag cagatcttcc tacagcatca   2940

ccaaataatc cagcagtaca tggtgaccct ggagaacctt ctcttcactg ctgaattaga   3000

ccctcatatc ttggccgtgt tccagcagtt ctgtgccctg caggcctaag ggtcattttt   3060

tcctcatgtc aaggtttttt ttgatatctt aaaataattt gtcttatttt ttgatggttt   3120

gaatgcttgc tttcttgtag tatcctttca cttcttaaag gaaacaaagg ggaagaggac   3180

agtgaatgaa catggcatta cttttaattg ccctgaaaag caaatacttc ctaacggcag   3240

taatgtgact atgaccatga tatattatat atgtgacaga tacaaattct ctgtgatcag   3300

tttgttattt tttttctcct taaggcacaa aataattggt ttgaggtatg tgaaacacta   3360

gaggtcaacc ttacatagta tatagaactg atgggtttac ccagctaccc agtagcataa   3420

cttttcacag ctcggggatg aattaacatg gctgaaataa aactaaaagt atggttttt    3479


<210>  6161
<211>  790
<212>  PRT
<213>  Homo sapiens

<400>  6161

Met Ser Arg Arg Arg His Ser Asp Glu Asn Asp Gly Gly Gln Pro His 
1               5                   10                  15


Lys Arg Arg Lys Thr Ser Asp Ala Asn Glu Thr Glu Asp His Leu Glu 
            20                  25                  30


Ser Leu Ile Cys Lys Val Gly Glu Lys Ser Ala Cys Ser Leu Glu Ser 
        35                  40                  45


Asn Leu Glu Gly Leu Ala Gly Val Leu Glu Ala Asp Leu Pro Asn Tyr 
    50                  55                  60


Lys Ser Lys Ile Leu Arg Leu Leu Cys Thr Val Ala Arg Leu Leu Pro 
65                  70                  75                  80


Glu Lys Leu Thr Ile Tyr Thr Thr Leu Val Gly Leu Leu Asn Ala Arg 
                85                  90                  95


Asn Tyr Asn Phe Gly Gly Glu Phe Val Glu Ala Met Ile Arg Gln Leu 
            100                 105                 110


Lys Glu Ser Leu Lys Ala Asn Asn Tyr Asn Glu Ala Val Tyr Leu Val 
        115                 120                 125


Arg Phe Leu Ser Asp Leu Val Asn Cys His Val Ile Ala Ala Pro Ser 
    130                 135                 140


Met Val Ala Met Phe Glu Asn Phe Val Ser Val Thr Gln Glu Glu Asp 
145                 150                 155                 160


Val Pro Gln Val Arg Arg Asp Trp Tyr Val Tyr Ala Phe Leu Ser Ser 
                165                 170                 175


Leu Pro Trp Val Gly Lys Glu Leu Tyr Glu Lys Lys Asp Ala Glu Met 
            180                 185                 190


Asp Arg Ile Phe Ala Asn Thr Glu Ser Tyr Leu Lys Arg Arg Gln Lys 
        195                 200                 205


Thr His Val Pro Met Leu Gln Val Trp Thr Ala Asp Lys Pro His Pro 
    210                 215                 220


Gln Glu Glu Tyr Leu Asp Cys Leu Trp Ala Gln Ile Gln Lys Leu Lys 
225                 230                 235                 240


Lys Asp Arg Trp Gln Glu Arg His Ile Leu Arg Pro Tyr Leu Ala Phe 
                245                 250                 255


Asp Ser Ile Leu Cys Glu Ala Leu Gln His Asn Leu Pro Pro Phe Thr 
            260                 265                 270


Pro Pro Pro His Thr Glu Asp Ser Val Tyr Pro Met Pro Arg Val Ile 
        275                 280                 285


Phe Arg Met Phe Asp Tyr Thr Asp Asp Pro Glu Gly Pro Val Met Pro 
    290                 295                 300


Gly Ser His Ser Val Glu Arg Phe Val Ile Glu Glu Asn Leu His Cys 
305                 310                 315                 320


Ile Ile Lys Ser His Trp Lys Glu Arg Lys Thr Cys Ala Ala Gln Leu 
                325                 330                 335


Val Ser Tyr Pro Gly Lys Asn Lys Ile Pro Leu Asn Tyr His Ile Val 
            340                 345                 350


Glu Val Ile Phe Ala Glu Leu Phe Gln Leu Pro Ala Pro Pro His Ile 
        355                 360                 365


Asp Val Met Tyr Thr Thr Leu Leu Ile Glu Leu Cys Lys Leu Gln Pro 
    370                 375                 380


Gly Ser Leu Pro Gln Val Leu Ala Gln Ala Thr Glu Met Leu Tyr Met 
385                 390                 395                 400


Arg Leu Asp Thr Met Asn Thr Thr Cys Val Asp Arg Phe Ile Asn Trp 
                405                 410                 415


Phe Ser His His Leu Ser Asn Phe Gln Phe Arg Trp Ser Trp Glu Asp 
            420                 425                 430


Trp Ser Asp Cys Leu Ser Gln Asp Pro Glu Ser Pro Lys Pro Lys Phe 
        435                 440                 445


Val Arg Glu Val Leu Glu Lys Cys Met Arg Leu Ser Tyr His Gln Arg 
    450                 455                 460


Ile Leu Asp Ile Val Pro Pro Thr Phe Ser Ala Leu Cys Pro Ala Asn 
465                 470                 475                 480


Pro Thr Cys Ile Tyr Lys Tyr Gly Asp Glu Ser Ser Asn Ser Leu Pro 
                485                 490                 495


Gly His Ser Val Ala Leu Cys Leu Ala Val Ala Phe Lys Ser Lys Ala 
            500                 505                 510


Thr Asn Asp Glu Ile Phe Ser Ile Leu Lys Asp Val Pro Asn Pro Asn 
        515                 520                 525


Gln Asp Asp Asp Asp Asp Glu Gly Phe Ser Phe Asn Pro Leu Lys Ile 
    530                 535                 540


Glu Val Phe Val Gln Thr Leu Leu His Leu Ala Ala Lys Ser Phe Ser 
545                 550                 555                 560


His Ser Phe Ser Ala Leu Ala Lys Phe His Glu Val Phe Lys Thr Leu 
                565                 570                 575


Ala Glu Ser Asp Glu Gly Lys Leu His Val Leu Arg Val Met Phe Glu 
            580                 585                 590


Val Trp Arg Asn His Pro Gln Met Ile Ala Val Leu Val Asp Lys Met 
        595                 600                 605


Ile Arg Thr Gln Ile Val Asp Cys Ala Ala Val Ala Asn Trp Ile Phe 
    610                 615                 620


Ser Ser Glu Leu Ser Arg Asp Phe Thr Arg Leu Phe Val Trp Glu Ile 
625                 630                 635                 640


Leu His Ser Thr Ile Arg Lys Met Asn Lys His Val Leu Lys Ile Gln 
                645                 650                 655


Lys Glu Leu Glu Glu Ala Lys Glu Lys Leu Ala Arg Gln His Lys Arg 
            660                 665                 670


Arg Ser Asp Asp Asp Asp Arg Ser Ser Asp Arg Lys Asp Gly Val Leu 
        675                 680                 685


Glu Glu Gln Ile Glu Arg Leu Gln Glu Lys Val Glu Ser Ala Gln Ser 
    690                 695                 700


Glu Gln Lys Asn Leu Phe Leu Val Ile Phe Gln Arg Phe Ile Met Ile 
705                 710                 715                 720


Leu Thr Glu His Leu Val Arg Cys Glu Thr Asp Gly Thr Ser Val Leu 
                725                 730                 735


Thr Pro Trp Tyr Lys Asn Cys Ile Glu Arg Leu Gln Gln Ile Phe Leu 
            740                 745                 750


Gln His His Gln Ile Ile Gln Gln Tyr Met Val Thr Leu Glu Asn Leu 
        755                 760                 765


Leu Phe Thr Ala Glu Leu Asp Pro His Ile Leu Ala Val Phe Gln Gln 
    770                 775                 780


Phe Cys Ala Leu Gln Ala 
785                 790


<210>  6162
<211>  5564
<212>  DNA
<213>  Homo sapiens

<400>  6162
ggcaaaagcc ggaaagtggg agtagatgag cacatacccg ccagtcctga tcctttctaa     60

ggtctctctt ccctgcactg tctccgccta gcaattgtca ctgctcaccg ccctcgagcc    120

tattcccccg ccgcgtattt gggtagaaaa gctcgctcgt gacgtcacca agctccggaa    180

gtctcctggc gtcggcgcaa gggccgccgg gaaaaccatt gagaggccac cgggaaacca    240

ttgagaagcc ccggaggacc ggcctgagcg gaggcggaga ctagagcggc cgccggcacg    300

acccgccttc aggcgtacga cgaccgcggc ccgggggctc tgagtggcca aagcggcggc    360

actttctgcg tggccccgga aggacataga gcggaaggcg ggagaaagaa gtagccggca    420

ggcggaggca gcccgagggg gcggttgcat gtgtgccaga cgttcgtagc ccactgagct    480

tcctcacgcc ggctgtcgca gcgcctagcc ccacccggcg gcctctcctg cgcttccggg    540

gccgtggcga gctagtgcgc ctgcgtgccg gcccatccgc gcgccttgca gctgtccttg    600

cgtcggccag cggccagaca gttcctgcag cgcttaccgc ctggcctctc ggttccgcgg    660

cgcaccggag ggcagcatgt cgcggcggcg gcacagcgac gagaacgacg gtgggcagcc    720

tcacaaaagg agaaagacct ctgatgcaaa tgaaactgaa gatcatttgg aatctttaat    780

atgtaaagta ggagaaaaga gtgcctgctc tttggagagc aacctagaag gcttggctgg    840

tgttttggaa gctgatcttc ctaactacaa gagcaagatc ttaaggcttc tttgtacagt    900

tgcacgccta ttacctgaga agctgacaat ttatacaaca ttagttggac tactgaatgc    960

caggaattac aattttggtg gagaatttgt agaagccatg attcgtcaac ttaaagaatc   1020

attgaaagca aacaattata atgaagccgt gtatttggtc cgttttttat ctgatcttgt   1080

gaattgtcat gtgattgccg ccccatcaat ggttgctatg tttgaaaatt ttgtaagcgt   1140

aactcaggaa gaagatgtac ctcaggtgcg acgagattgg tatgtgtatg catttctgtc   1200

atctttgccc tgggttggaa aggagttgta cgaaaagaaa gatgcagaga tggaccgcat   1260

ctttgccaac actgaaagct atcttaaaag acgccaaaag actcatgtac ccatgttaca   1320

ggtatggact gctgataaac cacatccaca agaagagtat ttagattgcc tgtgggccca   1380

gattcagaaa ttgaaaaagg atcgctggca ggaacggcac atcctaagac cttatcttgc   1440

ctttgacagc atcctgtgtg aagcactgca gcacaatctg cctcctttta caccacctcc   1500

tcacactgaa gattcagtgt acccaatgcc aagggtcatc ttcagaatgt ttgattacac   1560

agatgatccc gagggtcctg tcatgccagg gagtcattca gtggaaagat ttgtaataga   1620

agagaatctt cactgcatca ttaagtccca ctggaaggaa aggaagactt gtgctgcaca   1680

gttagtgagc tatccaggga agaacaagat ccccttgaac taccacatag ttgaggtgat   1740

ctttgcagag ctgtttcaac ttccagcacc ccctcacatt gatgtgatgt acacaacact   1800

cctcattgaa ctgtgcaaac ttcaacctgg ctctctaccc caagttcttg cacaggcaac   1860

tgaaatgcta tacatgcgtt tggacacaat gaacactacc tgtgtagaca ggtttattaa   1920

ttggttttct catcatctaa gtaacttcca gttccgttgg agctgggaag attggtcaga   1980

ttgtcttagt caagatcctg aaagtcccaa accgaagttt gtaagagaag ttctagaaaa   2040

atgtatgagg ttgtcttacc atcagcgtat attagatatt gttcctccta ccttctcagc   2100

tctgtgtcct gcaaacccaa cctgcattta caagtatgga gatgaaagta gcaattctct   2160

tcctggacat tctgttgccc tctgtttagc tgttgccttt aaaagtaagg caaccaatga   2220

tgaaatcttc agcattctga aagatgtacc aaatcctaac caggatgatg acgacgatga   2280

aggattcagt tttaacccat tgaaaataga agtctttgta cagactctgc tacacttggc   2340

agccaaatca ttcagccact ccttcagtgc tcttgcaaag tttcatgaag tcttcaaaac   2400

cctagctgaa agtgatgaag gaaagttaca tgtgctaaga gttatgtttg aggtctggag   2460

gaaccatcca cagatgattg ctgtactagt ggataagatg attcgtacac aaatagttga   2520

ttgtgctgcc gtagcaaatt ggatcttctc ttcagaacta tctcgtgact ttaccagatt   2580

gtttgtttgg gaaattttgc actctacaat tcgtaagatg aacaaacatg tcctgaagat   2640

ccagaaagag ctggaagaag ctaaagagaa acttgctagg caacacaaac ggcgaagtga   2700

tgatgacgac agaagcagtg acaggaaaga cggggttctt gaggaacaaa tagaacgact   2760

tcaggaaaaa gtggaatctg ctcagagtga acaaaagaat cttttcctcg ttatatttca   2820

gcggtttatc atgatcttga ccgagcacct agtacgatgc gaaactgatg ggaccagtgt   2880

attaacacca tggtataaga actgtataga gaggctgcag cagatcttcc tacagcatca   2940

ccaaataatc cagcagtaca tggtgaccct ggagaacctt ctcttcactg ctgaattaga   3000

ccctcatatc ttggccgtgt tccagcagtt ctgtgccctg caggcctaag ggtcattttt   3060

tcctcatgtc aaggtttttt ttgatatctt aaaataattt gtcttatttt ttgatggttt   3120

gaatgcttgc tttcttgtag tatcctttca cttcttaaag gaaacaaagg ggaagaggac   3180

agtgaatgaa catggcatta cttttaattg ccctgaaaag caaatacttc ctaacggcag   3240

taatgtgact atgaccatga tatattatat atgtgacaga tacaaattct ctgtgatcag   3300

tttgttattt tttttctcct taaggcacaa aataattggt ttgaggtatg tgaaacacta   3360

gaggtcaacc ttacatagta tatagaactg atgggtttac ccagctaccc agtagcataa   3420

cttttcacag ctcggggatg aattaacatg gctgaaataa aactaaaagt atggttttta   3480

aactttggca tttcatgatt tatcatctca ctctactcta aaactggtgg tttcttactg   3540

aaggtgttct ccatttgaaa ttttatcttc aaagtatttt taagtagtat ctttaagaca   3600

tgacttgtta gtaataaaag tgttactagt tggaagagta gctctcaaat ttgtcttaat   3660

gtaaatcacc tgggaatctt tcaagttatt ttgaaattta aaccaccgtc tgggggtgga   3720

acgcagacat cctcagtaat ccttaaagtt tccccaggtg attccaggtt tggtcaccat   3780

tatcttagag catctactca cttcctctag ccttggggtt atttgtccaa ggtcttgtag   3840

tgagttacag aatactaaag tggatgtaga agtggtcaga ttgactgaaa ctataccctg   3900

aattagatgt gagtttagat tttgtttata tggaacctga tccaaaaaac tacgaagtcc   3960

tgagcttgtt tcctgtatag tactgatgct gaaataagat gacagcagtt tgtaaaataa   4020

tacacaaata tgaggaattg tctgacattc caaatttcga ggatttttag acttttttca   4080

ttaaacctta gaaaaaaatt accagtaatc ctacaactac tggtagtgtt gttgtgcatt   4140

tgcacaaaat aggtataatt ttttcttatt acatcccaag tttatgatgc attaagcgtt   4200

ttgcatattt tgatatattt ttgctttggt ttaccataca ttttagtggc tacagaatgt   4260

agtctgctta ataaatggga attcctagaa tgtttaaata ccatactatt taagacaaaa   4320

tacaaaatat ccagaaaaat ccaggttgcg tggctggtta gtaaaggact aaaacccagg   4380

ttcttggcta aatgttttcg tttatactgt ttatctttcc cattgcttaa gcacagcaca   4440

aactatgtaa ttatatataa ttacagttga cccttgaaca acatgggttt gaactgtgtg   4500

agtctcctta cacacaggtt ttcttccacc cctgagatgg caagaccagc cccttgtctt   4560

cctcagcctg ctcaacgtga agatgatgag gatgaagacc tttatgatga tccacttcta   4620

cttattaaat agtaaatata tttttttctt atgattttat tttcttttct ctagcttcat   4680

aagaatatag catatgggct gggcgcagtg gctcacgcct gtaatcccag cactttggga   4740

ggctgaggcg ggcggatcac aaggtcagga gattgagacc atcctggcta acacagtgaa   4800

accctgtctc tactaaaaac acaaaaactt agccaggcgt ggtggtacat ggctgtagtc   4860

ccagctactt gggaggctga gacaggagaa tcgcttgaac ctgggaggtg gaggtttcag   4920

tgagccaaga ttgtgccact gcactccagc ctgggtgatg gagcgaggct ctgtctcaaa   4980

aaagaaaaaa aatatatagc atataacata caaaatgagt ttatcaactg tttgttattg   5040

gtaagtcagc agtgggctat tggtggttaa gttttggggg agtcaaaagt tacatgcaaa   5100

ttttttactg tgcggggtgt cagcatccct aaccccatgt tgttcaaggg tcaactgtag   5160

tttaaaatga ctcctgtctc aaaaaaccaa aggataacct ttaagggatt ggtaactttg   5220

actcaaaact gctttgtaat cttttcacaa tgtactgaaa agtgtggcta gttatgtttg   5280

atccacattc tagagaaatt tgtaggtttt aatttctttt ctcttggtcc tctcttcatg   5340

tataatggtt gcttttaaca gctgttcgct gatgtggtcc tgctctgtcc cagtctagca   5400

gctttagtgt atggaaaaat tgaactagga attgagtttt gaagaaataa aggtgtaaga   5460

gcaaacattc aacagttgct gtccccagta atgaagttca tacagacaaa agatggcatg   5520

tcactgtaca tcataccttg caataaatat tctgttaaat tgtg                    5564


<210>  6163
<211>  790
<212>  PRT
<213>  Homo sapiens

<400>  6163

Met Ser Arg Arg Arg His Ser Asp Glu Asn Asp Gly Gly Gln Pro His 
1               5                   10                  15


Lys Arg Arg Lys Thr Ser Asp Ala Asn Glu Thr Glu Asp His Leu Glu 
            20                  25                  30


Ser Leu Ile Cys Lys Val Gly Glu Lys Ser Ala Cys Ser Leu Glu Ser 
        35                  40                  45


Asn Leu Glu Gly Leu Ala Gly Val Leu Glu Ala Asp Leu Pro Asn Tyr 
    50                  55                  60


Lys Ser Lys Ile Leu Arg Leu Leu Cys Thr Val Ala Arg Leu Leu Pro 
65                  70                  75                  80


Glu Lys Leu Thr Ile Tyr Thr Thr Leu Val Gly Leu Leu Asn Ala Arg 
                85                  90                  95


Asn Tyr Asn Phe Gly Gly Glu Phe Val Glu Ala Met Ile Arg Gln Leu 
            100                 105                 110


Lys Glu Ser Leu Lys Ala Asn Asn Tyr Asn Glu Ala Val Tyr Leu Val 
        115                 120                 125


Arg Phe Leu Ser Asp Leu Val Asn Cys His Val Ile Ala Ala Pro Ser 
    130                 135                 140


Met Val Ala Met Phe Glu Asn Phe Val Ser Val Thr Gln Glu Glu Asp 
145                 150                 155                 160


Val Pro Gln Val Arg Arg Asp Trp Tyr Val Tyr Ala Phe Leu Ser Ser 
                165                 170                 175


Leu Pro Trp Val Gly Lys Glu Leu Tyr Glu Lys Lys Asp Ala Glu Met 
            180                 185                 190


Asp Arg Ile Phe Ala Asn Thr Glu Ser Tyr Leu Lys Arg Arg Gln Lys 
        195                 200                 205


Thr His Val Pro Met Leu Gln Val Trp Thr Ala Asp Lys Pro His Pro 
    210                 215                 220


Gln Glu Glu Tyr Leu Asp Cys Leu Trp Ala Gln Ile Gln Lys Leu Lys 
225                 230                 235                 240


Lys Asp Arg Trp Gln Glu Arg His Ile Leu Arg Pro Tyr Leu Ala Phe 
                245                 250                 255


Asp Ser Ile Leu Cys Glu Ala Leu Gln His Asn Leu Pro Pro Phe Thr 
            260                 265                 270


Pro Pro Pro His Thr Glu Asp Ser Val Tyr Pro Met Pro Arg Val Ile 
        275                 280                 285


Phe Arg Met Phe Asp Tyr Thr Asp Asp Pro Glu Gly Pro Val Met Pro 
    290                 295                 300


Gly Ser His Ser Val Glu Arg Phe Val Ile Glu Glu Asn Leu His Cys 
305                 310                 315                 320


Ile Ile Lys Ser His Trp Lys Glu Arg Lys Thr Cys Ala Ala Gln Leu 
                325                 330                 335


Val Ser Tyr Pro Gly Lys Asn Lys Ile Pro Leu Asn Tyr His Ile Val 
            340                 345                 350


Glu Val Ile Phe Ala Glu Leu Phe Gln Leu Pro Ala Pro Pro His Ile 
        355                 360                 365


Asp Val Met Tyr Thr Thr Leu Leu Ile Glu Leu Cys Lys Leu Gln Pro 
    370                 375                 380


Gly Ser Leu Pro Gln Val Leu Ala Gln Ala Thr Glu Met Leu Tyr Met 
385                 390                 395                 400


Arg Leu Asp Thr Met Asn Thr Thr Cys Val Asp Arg Phe Ile Asn Trp 
                405                 410                 415


Phe Ser His His Leu Ser Asn Phe Gln Phe Arg Trp Ser Trp Glu Asp 
            420                 425                 430


Trp Ser Asp Cys Leu Ser Gln Asp Pro Glu Ser Pro Lys Pro Lys Phe 
        435                 440                 445


Val Arg Glu Val Leu Glu Lys Cys Met Arg Leu Ser Tyr His Gln Arg 
    450                 455                 460


Ile Leu Asp Ile Val Pro Pro Thr Phe Ser Ala Leu Cys Pro Ala Asn 
465                 470                 475                 480


Pro Thr Cys Ile Tyr Lys Tyr Gly Asp Glu Ser Ser Asn Ser Leu Pro 
                485                 490                 495


Gly His Ser Val Ala Leu Cys Leu Ala Val Ala Phe Lys Ser Lys Ala 
            500                 505                 510


Thr Asn Asp Glu Ile Phe Ser Ile Leu Lys Asp Val Pro Asn Pro Asn 
        515                 520                 525


Gln Asp Asp Asp Asp Asp Glu Gly Phe Ser Phe Asn Pro Leu Lys Ile 
    530                 535                 540


Glu Val Phe Val Gln Thr Leu Leu His Leu Ala Ala Lys Ser Phe Ser 
545                 550                 555                 560


His Ser Phe Ser Ala Leu Ala Lys Phe His Glu Val Phe Lys Thr Leu 
                565                 570                 575


Ala Glu Ser Asp Glu Gly Lys Leu His Val Leu Arg Val Met Phe Glu 
            580                 585                 590


Val Trp Arg Asn His Pro Gln Met Ile Ala Val Leu Val Asp Lys Met 
        595                 600                 605


Ile Arg Thr Gln Ile Val Asp Cys Ala Ala Val Ala Asn Trp Ile Phe 
    610                 615                 620


Ser Ser Glu Leu Ser Arg Asp Phe Thr Arg Leu Phe Val Trp Glu Ile 
625                 630                 635                 640


Leu His Ser Thr Ile Arg Lys Met Asn Lys His Val Leu Lys Ile Gln 
                645                 650                 655


Lys Glu Leu Glu Glu Ala Lys Glu Lys Leu Ala Arg Gln His Lys Arg 
            660                 665                 670


Arg Ser Asp Asp Asp Asp Arg Ser Ser Asp Arg Lys Asp Gly Val Leu 
        675                 680                 685


Glu Glu Gln Ile Glu Arg Leu Gln Glu Lys Val Glu Ser Ala Gln Ser 
    690                 695                 700


Glu Gln Lys Asn Leu Phe Leu Val Ile Phe Gln Arg Phe Ile Met Ile 
705                 710                 715                 720


Leu Thr Glu His Leu Val Arg Cys Glu Thr Asp Gly Thr Ser Val Leu 
                725                 730                 735


Thr Pro Trp Tyr Lys Asn Cys Ile Glu Arg Leu Gln Gln Ile Phe Leu 
            740                 745                 750


Gln His His Gln Ile Ile Gln Gln Tyr Met Val Thr Leu Glu Asn Leu 
        755                 760                 765


Leu Phe Thr Ala Glu Leu Asp Pro His Ile Leu Ala Val Phe Gln Gln 
    770                 775                 780


Phe Cys Ala Leu Gln Ala 
785                 790


<210>  6164
<211>  5595
<212>  DNA
<213>  Homo sapiens

<400>  6164
ggcaaaagcc ggaaagtggg agtagatgag cacatacccg ccagtcctga tcctttctaa     60

ggtctctctt ccctgcactg tctccgccta gcaattgtca ctgctcaccg ccctcgagcc    120

tattcccccg ccgcgtattt gggtagaaaa gctcgctcgt gacgtcacca agctccggaa    180

gtctcctggc gtcggcgcaa gggccgccgg gaaaaccatt gagaggccac cgggaaacca    240

ttgagaagcc ccggaggacc ggcctgagcg gaggcggaga ctagagcggc cgccggcacg    300

acccgccttc aggcgtacga cgaccgcggc ccgggggctc tgagtggcca aagcggcggc    360

actttctgcg tggccccgga aggacataga gcggaaggcg ggagaaagaa gtagccggca    420

ggcggaggca gcccgagggg gcggttgcat gtgtgccaga cgttcgtagc ccactgagct    480

tcctcacgcc ggctgtcgca gcgcctagcc ccacccggcg gcctctcctg cgcttccggg    540

gccgtggcga gctagtgcgc ctgcgtgccg gcccatccgc gcgccttgca gctgtccttg    600

cgtcggccag cggccagaca gttcctgcag cgcttaccgc ctggcctctc ggttccgcgg    660

cgcaccggag ggcagcatgt cgcggcggcg gcacagcgac gagaacgacg gtgggcagcc    720

tcacaaaagg agaaagacct ctgatgcaaa tgaaactgaa gatcatttgg aatctttaat    780

atgtaaagta ggagaaaaga gtgcctgctc tttggagagc aacctagaag gcttggctgg    840

tgttttggaa gctgatcttc ctaactacaa gagcaagatc ttaaggcttc tttgtacagt    900

tgcacgccta ttacctgaga agctgacaat ttatacaaca ttagttggac tactgaatgc    960

caggaattac aattttggtg gagaatttgt agaagccatg attcgtcaac ttaaagaatc   1020

attgaaagca aacaattata atgaagccgt gtatttggtc cgttttttat ctgatcttgt   1080

gaattgtcat gtgattgccg ccccatcaat ggttgctatg tttgaaaatt ttgtaagcgt   1140

aactcaggaa gaagatgtac ctcaggtgcg acgagattgg tatgtgtatg catttctgtc   1200

atctttgccc tgggttggaa aggagttgta cgaaaagaaa gatgcagaga tggaccgcat   1260

ctttgccaac actgaaagct atcttaaaag acgccaaaag actcatgtac ccatgttaca   1320

ggtatggact gctgataaac cacatccaca agaagagtat ttagattgcc tgtgggccca   1380

gattcagaaa ttgaaaaagg atcgctggca ggaacggcac atcctaagac cttatcttgc   1440

ctttgacagc atcctgtgtg aagcactgca gcacaatctg cctcctttta caccacctcc   1500

tcacactgaa gattcagtgt acccaatgcc aagggtcatc ttcagaatgt ttgattacac   1560

agatgatccc gagggtcctg tcatgccagg gagtcattca gtggaaagat ttgtaataga   1620

agagaatctt cactgcatca ttaagtccca ctggaaggaa aggaagactt gtgctgcaca   1680

gttagtgagc tatccaggga agaacaagat ccccttgaac taccacatag ttgaggtgat   1740

ctttgcagag ctgtttcaac ttccagcacc ccctcacatt gatgtgatgt acacaacact   1800

cctcattgaa ctgtgcaaac ttcaacctgg ctctctaccc caagttcttg cacaggcaac   1860

tgaaatgcta tacatgcgtt tggacacaat gaacactacc tgtgtagaca ggtttattaa   1920

ttggttttct catcatctaa gtaacttcca gttccgttgg agctgggaag attggtcaga   1980

ttgtcttagt caagatcctg aaagtcccaa accgaagttt gtaagagaag ttctagaaaa   2040

atgtatgagg ttgtcttacc atcagcgtat attagatatt gttcctccta ccttctcagc   2100

tctgtgtcct gcaaacccaa cctgcattta caagtatgga gatgaaagta gcaattctct   2160

tcctggacat tctgttgccc tctgtttagc tgttgccttt aaaagtaagg caaccaatga   2220

tgaaatcttc agcattctga aagatgtacc aaatcctaac caggatgatg acgacgatga   2280

aggattcagt tttaacccat tgaaaataga agtctttgta cagactctgc tacacttggc   2340

agccaaatca ttcagccact ccttcagtgc tcttgcaaag tttcatgaag tcttcaaaac   2400

cctagctgaa agtgatgaag gaaagttaca tgtgctaaga gttatgtttg aggtctggag   2460

gaaccatcca cagatgattg ctgtactagt ggataagatg attcgtacac aaatagttga   2520

ttgtgctgcc gtagcaaatt ggatcttctc ttcagaacta tctcgtgact ttaccagatt   2580

gtttgtttgg gaaattttgc actctacaat tcgtaagatg aacaaacatg tcctgaagat   2640

ccagaaagag ctggaagaag ctaaagagaa acttgctagg caacacaaac ggcgaagtga   2700

tgatgacgac agaagcagtg acaggaaaga cggggttctt gaggaacaaa tagaacgact   2760

tcaggaaaaa gtggaatctg ctcagagtga acaaaagaat cttttcctcg ttatatttca   2820

gcggtttatc atgatcttga ccgagcacct agtacgatgc gaaactgatg ggaccagtgt   2880

attaacacca tggtataaga actgtataga gaggctgcag cagatcttcc tacagcatca   2940

ccaaataatc cagcagtaca tggtgaccct ggagaacctt ctcttcactg ctgaattaga   3000

ccctcatatc ttggccgtgt tccagcagtt ctgtgccctg caggcctaag ggtcattttt   3060

tcctcatgtc aaggtttttt ttgatatctt aaaataattt gtcttatttt ttgatggttt   3120

gaatgcttgc tttcttgtag tatcctttca cttcttaaag gaaacaaagg ggaagaggac   3180

agtgaatgaa catggcatta cttttaattg ccctgaaaag caaatacttc ctaacggcag   3240

taatgtgact atgaccatga tatattatat atgtgacaga tacaaattct ctgtgatcag   3300

tttgttattt tttttctcct taaggcacaa aataattggt ttgaggtatg tgaaacacta   3360

gaggtcaacc ttacatagta tatagaactg atgggtttac ccagctaccc agtagcataa   3420

cttttcacag ctcggggatg aattaacatg gctgaaataa aactaaaagt atggttttta   3480

aactttggca tttcatgatt tatcatctca ctctactcta aaactggtgg tttcttactg   3540

aaggtgttct ccatttgaaa ttttatcttc aaagtatttt taagtagtat ctttaagaca   3600

tgacttgtta gtaataaaag tgttactagt tggaagagta gctctcaaat ttgtcttaat   3660

gtaaatcacc tgggaatctt tcaagttatt ttgaaattta aaccaccgtc tgggggtgga   3720

acgcagacat cctcagtaat ccttaaagtt tccccaggtg attccaggtt tggtcaccat   3780

tatcttagag catctactca cttcctctag ccttggggtt atttgtccaa ggtcttgtag   3840

tgagttacag aatactaaag tggatgtaga agtggtcaga ttgactgaaa ctataccctg   3900

aattagatgt gagtttagat tttgtttata tggaacctga tccaaaaaac tacgaagtcc   3960

tgagcttgtt tcctgtatag tactgatgct gaaataagat gacagcagtt tgtaaaataa   4020

tacacaaata tgaggaattg tctgacattc caaatttcga ggatttttag acttttttca   4080

ttaaacctta gaaaaaaatt accagtaatc ctacaactac tggtagtgtt gttgtgcatt   4140

tgcacaaaat aggtataatt ttttcttatt acatcccaag tttatgatgc attaagcgtt   4200

ttgcatattt tgatatattt ttgctttggt ttaccataca ttttagtggc tacagaatgt   4260

agtctgctta ataaatggga attcctagaa tgtttaaata ccatactatt taagacaaaa   4320

tacaaaatat ccagaaaaat ccaggttgcg tggctggtta gtaaaggact aaaacccagg   4380

ttcttggcta aatgttttcg tttatactgt ttatctttcc cattgcttaa gcacagcaca   4440

aactatgtaa ttatatataa ttacagttga cccttgaaca acatgggttt gaactgtgtg   4500

agtctcctta cacacaggtt ttcttccacc cctgagatgg caagaccagc cccttgtctt   4560

cctcagcctg ctcaacgtga agatgatgag gatgaagacc tttatgatga tccacttcta   4620

cttattaaat agtaaatata tttttttctt atgattttat tttcttttct ctagcttcat   4680

aagaatatag catatgggct gggcgcagtg gctcacgcct gtaatcccag cactttggga   4740

ggctgaggcg ggcggatcac aaggtcagga gattgagacc atcctggcta acacagtgaa   4800

accctgtctc tactaaaaac acaaaaactt agccaggcgt ggtggtacat ggctgtagtc   4860

ccagctactt gggaggctga gacaggagaa tcgcttgaac ctgggaggtg gaggtttcag   4920

tgagccaaga ttgtgccact gcactccagc ctgggtgatg gagcgaggct ctgtctcaaa   4980

aaagaaaaaa aatatatagc atataacata caaaatgagt ttatcaactg tttgttattg   5040

gtaagtcagc agtgggctat tggtggttaa gttttggggg agtcaaaagt tacatgcaaa   5100

ttttttactg tgcggggtgt cagcatccct aaccccatgt tgttcaaggg tcaactgtag   5160

tttaaaatga ctcctgtctc aaaaaaccaa aggataacct ttaagggatt ggtaactttg   5220

actcaaaact gctttgtaat cttttcacaa tgtactgaaa agtgtggcta gttatgtttg   5280

atccacattc tagagaaatt tgtaggtttt aatttctttt ctcttggtcc tctcttcatg   5340

tataatggtt gcttttaaca gctgttcgct gatgtggtcc tgctctgtcc cagtctagca   5400

gctttagtgt atggaaaaat tgaactagga attgagtttt gaagaaataa aggtgtaaga   5460

gcaaacattc aacagttgct gtccccagta atgaagttca tacagacaaa agatggcatg   5520

tcactgtaca tcataccttg caataaatat tctgttaaat tgtgctggtg caatttaaca   5580

tgcttttgtc aaagt                                                    5595


<210>  6165
<211>  790
<212>  PRT
<213>  Homo sapiens

<400>  6165

Met Ser Arg Arg Arg His Ser Asp Glu Asn Asp Gly Gly Gln Pro His 
1               5                   10                  15


Lys Arg Arg Lys Thr Ser Asp Ala Asn Glu Thr Glu Asp His Leu Glu 
            20                  25                  30


Ser Leu Ile Cys Lys Val Gly Glu Lys Ser Ala Cys Ser Leu Glu Ser 
        35                  40                  45


Asn Leu Glu Gly Leu Ala Gly Val Leu Glu Ala Asp Leu Pro Asn Tyr 
    50                  55                  60


Lys Ser Lys Ile Leu Arg Leu Leu Cys Thr Val Ala Arg Leu Leu Pro 
65                  70                  75                  80


Glu Lys Leu Thr Ile Tyr Thr Thr Leu Val Gly Leu Leu Asn Ala Arg 
                85                  90                  95


Asn Tyr Asn Phe Gly Gly Glu Phe Val Glu Ala Met Ile Arg Gln Leu 
            100                 105                 110


Lys Glu Ser Leu Lys Ala Asn Asn Tyr Asn Glu Ala Val Tyr Leu Val 
        115                 120                 125


Arg Phe Leu Ser Asp Leu Val Asn Cys His Val Ile Ala Ala Pro Ser 
    130                 135                 140


Met Val Ala Met Phe Glu Asn Phe Val Ser Val Thr Gln Glu Glu Asp 
145                 150                 155                 160


Val Pro Gln Val Arg Arg Asp Trp Tyr Val Tyr Ala Phe Leu Ser Ser 
                165                 170                 175


Leu Pro Trp Val Gly Lys Glu Leu Tyr Glu Lys Lys Asp Ala Glu Met 
            180                 185                 190


Asp Arg Ile Phe Ala Asn Thr Glu Ser Tyr Leu Lys Arg Arg Gln Lys 
        195                 200                 205


Thr His Val Pro Met Leu Gln Val Trp Thr Ala Asp Lys Pro His Pro 
    210                 215                 220


Gln Glu Glu Tyr Leu Asp Cys Leu Trp Ala Gln Ile Gln Lys Leu Lys 
225                 230                 235                 240


Lys Asp Arg Trp Gln Glu Arg His Ile Leu Arg Pro Tyr Leu Ala Phe 
                245                 250                 255


Asp Ser Ile Leu Cys Glu Ala Leu Gln His Asn Leu Pro Pro Phe Thr 
            260                 265                 270


Pro Pro Pro His Thr Glu Asp Ser Val Tyr Pro Met Pro Arg Val Ile 
        275                 280                 285


Phe Arg Met Phe Asp Tyr Thr Asp Asp Pro Glu Gly Pro Val Met Pro 
    290                 295                 300


Gly Ser His Ser Val Glu Arg Phe Val Ile Glu Glu Asn Leu His Cys 
305                 310                 315                 320


Ile Ile Lys Ser His Trp Lys Glu Arg Lys Thr Cys Ala Ala Gln Leu 
                325                 330                 335


Val Ser Tyr Pro Gly Lys Asn Lys Ile Pro Leu Asn Tyr His Ile Val 
            340                 345                 350


Glu Val Ile Phe Ala Glu Leu Phe Gln Leu Pro Ala Pro Pro His Ile 
        355                 360                 365


Asp Val Met Tyr Thr Thr Leu Leu Ile Glu Leu Cys Lys Leu Gln Pro 
    370                 375                 380


Gly Ser Leu Pro Gln Val Leu Ala Gln Ala Thr Glu Met Leu Tyr Met 
385                 390                 395                 400


Arg Leu Asp Thr Met Asn Thr Thr Cys Val Asp Arg Phe Ile Asn Trp 
                405                 410                 415


Phe Ser His His Leu Ser Asn Phe Gln Phe Arg Trp Ser Trp Glu Asp 
            420                 425                 430


Trp Ser Asp Cys Leu Ser Gln Asp Pro Glu Ser Pro Lys Pro Lys Phe 
        435                 440                 445


Val Arg Glu Val Leu Glu Lys Cys Met Arg Leu Ser Tyr His Gln Arg 
    450                 455                 460


Ile Leu Asp Ile Val Pro Pro Thr Phe Ser Ala Leu Cys Pro Ala Asn 
465                 470                 475                 480


Pro Thr Cys Ile Tyr Lys Tyr Gly Asp Glu Ser Ser Asn Ser Leu Pro 
                485                 490                 495


Gly His Ser Val Ala Leu Cys Leu Ala Val Ala Phe Lys Ser Lys Ala 
            500                 505                 510


Thr Asn Asp Glu Ile Phe Ser Ile Leu Lys Asp Val Pro Asn Pro Asn 
        515                 520                 525


Gln Asp Asp Asp Asp Asp Glu Gly Phe Ser Phe Asn Pro Leu Lys Ile 
    530                 535                 540


Glu Val Phe Val Gln Thr Leu Leu His Leu Ala Ala Lys Ser Phe Ser 
545                 550                 555                 560


His Ser Phe Ser Ala Leu Ala Lys Phe His Glu Val Phe Lys Thr Leu 
                565                 570                 575


Ala Glu Ser Asp Glu Gly Lys Leu His Val Leu Arg Val Met Phe Glu 
            580                 585                 590


Val Trp Arg Asn His Pro Gln Met Ile Ala Val Leu Val Asp Lys Met 
        595                 600                 605


Ile Arg Thr Gln Ile Val Asp Cys Ala Ala Val Ala Asn Trp Ile Phe 
    610                 615                 620


Ser Ser Glu Leu Ser Arg Asp Phe Thr Arg Leu Phe Val Trp Glu Ile 
625                 630                 635                 640


Leu His Ser Thr Ile Arg Lys Met Asn Lys His Val Leu Lys Ile Gln 
                645                 650                 655


Lys Glu Leu Glu Glu Ala Lys Glu Lys Leu Ala Arg Gln His Lys Arg 
            660                 665                 670


Arg Ser Asp Asp Asp Asp Arg Ser Ser Asp Arg Lys Asp Gly Val Leu 
        675                 680                 685


Glu Glu Gln Ile Glu Arg Leu Gln Glu Lys Val Glu Ser Ala Gln Ser 
    690                 695                 700


Glu Gln Lys Asn Leu Phe Leu Val Ile Phe Gln Arg Phe Ile Met Ile 
705                 710                 715                 720


Leu Thr Glu His Leu Val Arg Cys Glu Thr Asp Gly Thr Ser Val Leu 
                725                 730                 735


Thr Pro Trp Tyr Lys Asn Cys Ile Glu Arg Leu Gln Gln Ile Phe Leu 
            740                 745                 750


Gln His His Gln Ile Ile Gln Gln Tyr Met Val Thr Leu Glu Asn Leu 
        755                 760                 765


Leu Phe Thr Ala Glu Leu Asp Pro His Ile Leu Ala Val Phe Gln Gln 
    770                 775                 780


Phe Cys Ala Leu Gln Ala 
785                 790


<210>  6166
<211>  6689
<212>  DNA
<213>  Homo sapiens

<400>  6166
ggcaaaagcc ggaaagtggg agtagatgag cacatacccg ccagtcctga tcctttctaa     60

ggtctctctt ccctgcactg tctccgccta gcaattgtca ctgctcaccg ccctcgagcc    120

tattcccccg ccgcgtattt gggtagaaaa gctcgctcgt gacgtcacca agctccggaa    180

gtctcctggc gtcggcgcaa gggccgccgg gaaaaccatt gagaggccac cgggaaacca    240

ttgagaagcc ccggaggacc ggcctgagcg gaggcggaga ctagagcggc cgccggcacg    300

acccgccttc aggcgtacga cgaccgcggc ccgggggctc tgagtggcca aagcggcggc    360

actttctgcg tggccccgga aggacataga gcggaaggcg ggagaaagaa gtagccggca    420

ggcggaggca gcccgagggg gcggttgcat gtgtgccaga cgttcgtagc ccactgagct    480

tcctcacgcc ggctgtcgca gcgcctagcc ccacccggcg gcctctcctg cgcttccggg    540

gccgtggcga gctagtgcgc ctgcgtgccg gcccatccgc gcgccttgca gctgtccttg    600

cgtcggccag cggccagaca gttcctgcag cgcttaccgc ctggcctctc ggttccgcgg    660

cgcaccggag ggcagcatgt cgcggcggcg gcacagcgac gagaacgacg gtgggcagcc    720

tcacaaaagg agaaagacct ctgatgcaaa tgaaactgaa gatcatttgg aatctttaat    780

atgtaaagta ggagaaaaga gtgcctgctc tttggagagc aacctagaag gcttggctgg    840

tgttttggaa gctgatcttc ctaactacaa gagcaagatc ttaaggcttc tttgtacagt    900

tgcacgccta ttacctgaga agctgacaat ttatacaaca ttagttggac tactgaatgc    960

caggaattac aattttggtg gagaatttgt agaagccatg attcgtcaac ttaaagaatc   1020

attgaaagca aacaattata atgaagccgt gtatttggtc cgttttttat ctgatcttgt   1080

gaattgtcat gtgattgccg ccccatcaat ggttgctatg tttgaaaatt ttgtaagcgt   1140

aactcaggaa gaagatgtac ctcaggtgcg acgagattgg tatgtgtatg catttctgtc   1200

atctttgccc tgggttggaa aggagttgta cgaaaagaaa gatgcagaga tggaccgcat   1260

ctttgccaac actgaaagct atcttaaaag acgccaaaag actcatgtac ccatgttaca   1320

ggtatggact gctgataaac cacatccaca agaagagtat ttagattgcc tgtgggccca   1380

gattcagaaa ttgaaaaagg atcgctggca ggaacggcac atcctaagac cttatcttgc   1440

ctttgacagc atcctgtgtg aagcactgca gcacaatctg cctcctttta caccacctcc   1500

tcacactgaa gattcagtgt acccaatgcc aagggtcatc ttcagaatgt ttgattacac   1560

agatgatccc gagggtcctg tcatgccagg gagtcattca gtggaaagat ttgtaataga   1620

agagaatctt cactgcatca ttaagtccca ctggaaggaa aggaagactt gtgctgcaca   1680

gttagtgagc tatccaggga agaacaagat ccccttgaac taccacatag ttgaggtgat   1740

ctttgcagag ctgtttcaac ttccagcacc ccctcacatt gatgtgatgt acacaacact   1800

cctcattgaa ctgtgcaaac ttcaacctgg ctctctaccc caagttcttg cacaggcaac   1860

tgaaatgcta tacatgcgtt tggacacaat gaacactacc tgtgtagaca ggtttattaa   1920

ttggttttct catcatctaa gtaacttcca gttccgttgg agctgggaag attggtcaga   1980

ttgtcttagt caagatcctg aaagtcccaa accgaagttt gtaagagaag ttctagaaaa   2040

atgtatgagg ttgtcttacc atcagcgtat attagatatt gttcctccta ccttctcagc   2100

tctgtgtcct gcaaacccaa cctgcattta caagtatgga gatgaaagta gcaattctct   2160

tcctggacat tctgttgccc tctgtttagc tgttgccttt aaaagtaagg caaccaatga   2220

tgaaatcttc agcattctga aagatgtacc aaatcctaac caggatgatg acgacgatga   2280

aggattcagt tttaacccat tgaaaataga agtctttgta cagactctgc tacacttggc   2340

agccaaatca ttcagccact ccttcagtgc tcttgcaaag tttcatgaag tcttcaaaac   2400

cctagctgaa agtgatgaag gaaagttaca tgtgctaaga gttatgtttg aggtctggag   2460

gaaccatcca cagatgattg ctgtactagt ggataagatg attcgtacac aaatagttga   2520

ttgtgctgcc gtagcaaatt ggatcttctc ttcagaacta tctcgtgact ttaccagatt   2580

gtttgtttgg gaaattttgc actctacaat tcgtaagatg aacaaacatg tcctgaagat   2640

ccagaaagag ctggaagaag ctaaagagaa acttgctagg caacacaaac ggcgaagtga   2700

tgatgacgac agaagcagtg acaggaaaga cggggttctt gaggaacaaa tagaacgact   2760

tcaggaaaaa gtggaatctg ctcagagtga acaaaagaat cttttcctcg ttatatttca   2820

gcggtttatc atgatcttga ccgagcacct agtacgatgc gaaactgatg ggaccagtgt   2880

attaacacca tggtataaga actgtataga gaggctgcag cagatcttcc tacagcatca   2940

ccaaataatc cagcagtaca tggtgaccct ggagaacctt ctcttcactg ctgaattaga   3000

ccctcatatc ttggccgtgt tccagcagtt ctgtgccctg caggcctaag ggtcattttt   3060

tcctcatgtc aaggtttttt ttgatatctt aaaataattt gtcttatttt ttgatggttt   3120

gaatgcttgc tttcttgtag tatcctttca cttcttaaag gaaacaaagg ggaagaggac   3180

agtgaatgaa catggcatta cttttaattg ccctgaaaag caaatacttc ctaacggcag   3240

taatgtgact atgaccatga tatattatat atgtgacaga tacaaattct ctgtgatcag   3300

tttgttattt tttttctcct taaggcacaa aataattggt ttgaggtatg tgaaacacta   3360

gaggtcaacc ttacatagta tatagaactg atgggtttac ccagctaccc agtagcataa   3420

cttttcacag ctcggggatg aattaacatg gctgaaataa aactaaaagt atggttttta   3480

aactttggca tttcatgatt tatcatctca ctctactcta aaactggtgg tttcttactg   3540

aaggtgttct ccatttgaaa ttttatcttc aaagtatttt taagtagtat ctttaagaca   3600

tgacttgtta gtaataaaag tgttactagt tggaagagta gctctcaaat ttgtcttaat   3660

gtaaatcacc tgggaatctt tcaagttatt ttgaaattta aaccaccgtc tgggggtgga   3720

acgcagacat cctcagtaat ccttaaagtt tccccaggtg attccaggtt tggtcaccat   3780

tatcttagag catctactca cttcctctag ccttggggtt atttgtccaa ggtcttgtag   3840

tgagttacag aatactaaag tggatgtaga agtggtcaga ttgactgaaa ctataccctg   3900

aattagatgt gagtttagat tttgtttata tggaacctga tccaaaaaac tacgaagtcc   3960

tgagcttgtt tcctgtatag tactgatgct gaaataagat gacagcagtt tgtaaaataa   4020

tacacaaata tgaggaattg tctgacattc caaatttcga ggatttttag acttttttca   4080

ttaaacctta gaaaaaaatt accagtaatc ctacaactac tggtagtgtt gttgtgcatt   4140

tgcacaaaat aggtataatt ttttcttatt acatcccaag tttatgatgc attaagcgtt   4200

ttgcatattt tgatatattt ttgctttggt ttaccataca ttttagtggc tacagaatgt   4260

agtctgctta ataaatggga attcctagaa tgtttaaata ccatactatt taagacaaaa   4320

tacaaaatat ccagaaaaat ccaggttgcg tggctggtta gtaaaggact aaaacccagg   4380

ttcttggcta aatgttttcg tttatactgt ttatctttcc cattgcttaa gcacagcaca   4440

aactatgtaa ttatatataa ttacagttga cccttgaaca acatgggttt gaactgtgtg   4500

agtctcctta cacacaggtt ttcttccacc cctgagatgg caagaccagc cccttgtctt   4560

cctcagcctg ctcaacgtga agatgatgag gatgaagacc tttatgatga tccacttcta   4620

cttattaaat agtaaatata tttttttctt atgattttat tttcttttct ctagcttcat   4680

aagaatatag catatgggct gggcgcagtg gctcacgcct gtaatcccag cactttggga   4740

ggctgaggcg ggcggatcac aaggtcagga gattgagacc atcctggcta acacagtgaa   4800

accctgtctc tactaaaaac acaaaaactt agccaggcgt ggtggtacat ggctgtagtc   4860

ccagctactt gggaggctga gacaggagaa tcgcttgaac ctgggaggtg gaggtttcag   4920

tgagccaaga ttgtgccact gcactccagc ctgggtgatg gagcgaggct ctgtctcaaa   4980

aaagaaaaaa aatatatagc atataacata caaaatgagt ttatcaactg tttgttattg   5040

gtaagtcagc agtgggctat tggtggttaa gttttggggg agtcaaaagt tacatgcaaa   5100

ttttttactg tgcggggtgt cagcatccct aaccccatgt tgttcaaggg tcaactgtag   5160

tttaaaatga ctcctgtctc aaaaaaccaa aggataacct ttaagggatt ggtaactttg   5220

actcaaaact gctttgtaat cttttcacaa tgtactgaaa agtgtggcta gttatgtttg   5280

atccacattc tagagaaatt tgtaggtttt aatttctttt ctcttggtcc tctcttcatg   5340

tataatggtt gcttttaaca gctgttcgct gatgtggtcc tgctctgtcc cagtctagca   5400

gctttagtgt atggaaaaat tgaactagga attgagtttt gaagaaataa aggtgtaaga   5460

gcaaacattc aacagttgct gtccccagta atgaagttca tacagacaaa agatggcatg   5520

tcactgtaca tcataccttg caataaatat tctgttaaat tgtgctggtg caatttaaca   5580

tgcttttgtc aaagtaaaca tactgttttc ctaatttata actgtacttg aaaatgaaag   5640

atgaggaagg gaccttgcca acctatgtag agcaggttta gctgttagtg atttctggat   5700

accaggattg tcttaaactg gtaagggtgt agagggtgaa tagaagcatc ccttaactag   5760

acaaatctat tttctgtaac atagtggcct tggtaataca tgctcattaa ctagtggtta   5820

ttatgtgcca ggtgctatag gttcacccta ttaactactt caaacagtcc tttgagatga   5880

ttatgccctc tttacagata aaaacaggtt ttggagtaat ttacccacgg tccacagcta   5940

gtaagtggaa tttgaaccta gatccagttg gcccaagagc tccttccccg cccccataat   6000

gctcttacaa caacctgaac ccctagttat tctgttgtca tcatctgttg tcatcaagct   6060

gaaagctttt ttccccagag acatcttgct gcccattcag aatcaatttt tactaagctg   6120

taatatttag catagcacgt attagtcatt gagtgtgaag gtgtttaaaa aaaaatcaaa   6180

cttgaaaaat acacaaacat ttctgtgtag tctgaattat ttggacatga cttgttttga   6240

cttagccttt ctccaagcat aatctccatt aaagaaaaaa aaatggaaat gtttaaactt   6300

cctattctat ttgtacagta ggataaaatg tcatgtcaaa caatttgaaa atatcaggtt   6360

attttaacta actggaattt gtttttgtca aaaaataatg catagaccca ataattcttt   6420

tgacaagcta caggaaaatt tcactaaagt tgatgcagat gcctgcggtg atgtgagact   6480

tcaccttcct ttccttagaa gtctgaaagc agcatggaag caagcctggg actaaatgaa   6540

catactccta aggcacttag gtgcatgcct ggcacctggt tggtaaatgc tcagtaaatg   6600

ttagcactac ttaaaataaa catcagtgcc ttctttgatc aacaatcaga tagtcaacca   6660

tgaaaacagc tcttttccat tttaatcca                                     6689


<210>  6167
<211>  790
<212>  PRT
<213>  Homo sapiens

<400>  6167

Met Ser Arg Arg Arg His Ser Asp Glu Asn Asp Gly Gly Gln Pro His 
1               5                   10                  15


Lys Arg Arg Lys Thr Ser Asp Ala Asn Glu Thr Glu Asp His Leu Glu 
            20                  25                  30


Ser Leu Ile Cys Lys Val Gly Glu Lys Ser Ala Cys Ser Leu Glu Ser 
        35                  40                  45


Asn Leu Glu Gly Leu Ala Gly Val Leu Glu Ala Asp Leu Pro Asn Tyr 
    50                  55                  60


Lys Ser Lys Ile Leu Arg Leu Leu Cys Thr Val Ala Arg Leu Leu Pro 
65                  70                  75                  80


Glu Lys Leu Thr Ile Tyr Thr Thr Leu Val Gly Leu Leu Asn Ala Arg 
                85                  90                  95


Asn Tyr Asn Phe Gly Gly Glu Phe Val Glu Ala Met Ile Arg Gln Leu 
            100                 105                 110


Lys Glu Ser Leu Lys Ala Asn Asn Tyr Asn Glu Ala Val Tyr Leu Val 
        115                 120                 125


Arg Phe Leu Ser Asp Leu Val Asn Cys His Val Ile Ala Ala Pro Ser 
    130                 135                 140


Met Val Ala Met Phe Glu Asn Phe Val Ser Val Thr Gln Glu Glu Asp 
145                 150                 155                 160


Val Pro Gln Val Arg Arg Asp Trp Tyr Val Tyr Ala Phe Leu Ser Ser 
                165                 170                 175


Leu Pro Trp Val Gly Lys Glu Leu Tyr Glu Lys Lys Asp Ala Glu Met 
            180                 185                 190


Asp Arg Ile Phe Ala Asn Thr Glu Ser Tyr Leu Lys Arg Arg Gln Lys 
        195                 200                 205


Thr His Val Pro Met Leu Gln Val Trp Thr Ala Asp Lys Pro His Pro 
    210                 215                 220


Gln Glu Glu Tyr Leu Asp Cys Leu Trp Ala Gln Ile Gln Lys Leu Lys 
225                 230                 235                 240


Lys Asp Arg Trp Gln Glu Arg His Ile Leu Arg Pro Tyr Leu Ala Phe 
                245                 250                 255


Asp Ser Ile Leu Cys Glu Ala Leu Gln His Asn Leu Pro Pro Phe Thr 
            260                 265                 270


Pro Pro Pro His Thr Glu Asp Ser Val Tyr Pro Met Pro Arg Val Ile 
        275                 280                 285


Phe Arg Met Phe Asp Tyr Thr Asp Asp Pro Glu Gly Pro Val Met Pro 
    290                 295                 300


Gly Ser His Ser Val Glu Arg Phe Val Ile Glu Glu Asn Leu His Cys 
305                 310                 315                 320


Ile Ile Lys Ser His Trp Lys Glu Arg Lys Thr Cys Ala Ala Gln Leu 
                325                 330                 335


Val Ser Tyr Pro Gly Lys Asn Lys Ile Pro Leu Asn Tyr His Ile Val 
            340                 345                 350


Glu Val Ile Phe Ala Glu Leu Phe Gln Leu Pro Ala Pro Pro His Ile 
        355                 360                 365


Asp Val Met Tyr Thr Thr Leu Leu Ile Glu Leu Cys Lys Leu Gln Pro 
    370                 375                 380


Gly Ser Leu Pro Gln Val Leu Ala Gln Ala Thr Glu Met Leu Tyr Met 
385                 390                 395                 400


Arg Leu Asp Thr Met Asn Thr Thr Cys Val Asp Arg Phe Ile Asn Trp 
                405                 410                 415


Phe Ser His His Leu Ser Asn Phe Gln Phe Arg Trp Ser Trp Glu Asp 
            420                 425                 430


Trp Ser Asp Cys Leu Ser Gln Asp Pro Glu Ser Pro Lys Pro Lys Phe 
        435                 440                 445


Val Arg Glu Val Leu Glu Lys Cys Met Arg Leu Ser Tyr His Gln Arg 
    450                 455                 460


Ile Leu Asp Ile Val Pro Pro Thr Phe Ser Ala Leu Cys Pro Ala Asn 
465                 470                 475                 480


Pro Thr Cys Ile Tyr Lys Tyr Gly Asp Glu Ser Ser Asn Ser Leu Pro 
                485                 490                 495


Gly His Ser Val Ala Leu Cys Leu Ala Val Ala Phe Lys Ser Lys Ala 
            500                 505                 510


Thr Asn Asp Glu Ile Phe Ser Ile Leu Lys Asp Val Pro Asn Pro Asn 
        515                 520                 525


Gln Asp Asp Asp Asp Asp Glu Gly Phe Ser Phe Asn Pro Leu Lys Ile 
    530                 535                 540


Glu Val Phe Val Gln Thr Leu Leu His Leu Ala Ala Lys Ser Phe Ser 
545                 550                 555                 560


His Ser Phe Ser Ala Leu Ala Lys Phe His Glu Val Phe Lys Thr Leu 
                565                 570                 575


Ala Glu Ser Asp Glu Gly Lys Leu His Val Leu Arg Val Met Phe Glu 
            580                 585                 590


Val Trp Arg Asn His Pro Gln Met Ile Ala Val Leu Val Asp Lys Met 
        595                 600                 605


Ile Arg Thr Gln Ile Val Asp Cys Ala Ala Val Ala Asn Trp Ile Phe 
    610                 615                 620


Ser Ser Glu Leu Ser Arg Asp Phe Thr Arg Leu Phe Val Trp Glu Ile 
625                 630                 635                 640


Leu His Ser Thr Ile Arg Lys Met Asn Lys His Val Leu Lys Ile Gln 
                645                 650                 655


Lys Glu Leu Glu Glu Ala Lys Glu Lys Leu Ala Arg Gln His Lys Arg 
            660                 665                 670


Arg Ser Asp Asp Asp Asp Arg Ser Ser Asp Arg Lys Asp Gly Val Leu 
        675                 680                 685


Glu Glu Gln Ile Glu Arg Leu Gln Glu Lys Val Glu Ser Ala Gln Ser 
    690                 695                 700


Glu Gln Lys Asn Leu Phe Leu Val Ile Phe Gln Arg Phe Ile Met Ile 
705                 710                 715                 720


Leu Thr Glu His Leu Val Arg Cys Glu Thr Asp Gly Thr Ser Val Leu 
                725                 730                 735


Thr Pro Trp Tyr Lys Asn Cys Ile Glu Arg Leu Gln Gln Ile Phe Leu 
            740                 745                 750


Gln His His Gln Ile Ile Gln Gln Tyr Met Val Thr Leu Glu Asn Leu 
        755                 760                 765


Leu Phe Thr Ala Glu Leu Asp Pro His Ile Leu Ala Val Phe Gln Gln 
    770                 775                 780


Phe Cys Ala Leu Gln Ala 
785                 790


<210>  6168
<211>  285
<212>  DNA
<213>  Homo sapiens

<400>  6168
ttactctgag gttctcgcgg caagacccaa atggacagtg atttggctgc cagctggtgt     60

taaaaacaag ccaactccaa gaaagttatg gattacctct aagtgagaaa aaggaagcat    120

tagaacaaca aagaaaagaa caaaagactc aagttctcca gcccccaaaa ttattccatc    180

tttatgaagg caacactgat ctccacgagc acaatcatcc aaacggagat gggaacccct    240

gttctaactc tctcagaggc ctgaagttag ttttctagca ctctc                    285


<210>  6169
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  6169

Phe Gly Cys Gln Leu Val Leu Lys Thr Ser Gln Leu Gln Glu Ser Tyr 
1               5                   10                  15


Gly Leu Pro Leu Ser Glu Lys Lys Glu Ala Leu Glu Gln Gln Arg Lys 
            20                  25                  30


Glu Gln Lys Thr Gln Val Leu Gln Pro Pro Lys Leu Phe His Leu Tyr 
        35                  40                  45


Glu Gly Asn Thr Asp Leu His Glu His Asn His Pro Asn Gly Asp Gly 
    50                  55                  60


Asn Pro Cys Ser Asn Ser Leu Arg Gly Leu Lys Leu Val Phe 
65                  70                  75


<210>  6170
<211>  536
<212>  DNA
<213>  Homo sapiens

<400>  6170
ttaacctatt agaaaaagct ttcacatacg gtatttatat gtgattaaat attgaccttg     60

ggataaagag catcctattt tgaaaggaag aatttaaaaa aaatttttct cagttattta    120

actgttcatt agaatagtct tgaaacctga tctgtcattc cccttacccc caattctgtg    180

tttagattct cttcctggac attctgttgc cctctgttta gctgttgcct ttaaaagtaa    240

ggcaaccaat gatgaaatct tcagcattct gaaagatgta ccaaatccta accaggatga    300

tgacgacgat gaaggattca gttttaaccc attgaaaata gaagtctttg tacagactct    360

gctacacttg gcagccaaat cattcagcca ctccttcagt gctcttgcaa agtatgtatg    420

agtacagagc cttgcttgag agtttggaat tttgcttggt gaacaccagt ggtatggtaa    480

tttttaccta agattgttga atatgaagat cttaatagtg tataattgga cacagt        536


<210>  6171
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  6171

Leu Phe Ile Arg Ile Val Leu Lys Pro Asp Leu Ser Phe Pro Leu Pro 
1               5                   10                  15


Pro Ile Leu Cys Leu Asp Ser Leu Pro Gly His Ser Val Ala Leu Cys 
            20                  25                  30


Leu Ala Val Ala Phe Lys Ser Lys Ala Thr Asn Asp Glu Ile Phe Ser 
        35                  40                  45


Ile Leu Lys Asp Val Pro Asn Pro Asn Gln Asp Asp Asp Asp Asp Glu 
    50                  55                  60


Gly Phe Ser Phe Asn Pro Leu Lys Ile Glu Val Phe Val Gln Thr Leu 
65                  70                  75                  80


Leu His Leu Ala Ala Lys Ser Phe Ser His Ser Phe Ser Ala Leu Ala 
                85                  90                  95


Lys Tyr Val 



<210>  6172
<211>  864
<212>  DNA
<213>  Homo sapiens

<400>  6172
ctccttttcc tactgtggca ttctgttatc tgaagtcaaa cgtacctgaa tgtgtcctat     60

tgtgttactc aactcacttc tgaatatggt tctgttttgc ataccaccaa cccacataac    120

catttctgaa tctcttgttt cacactgctc cagtgacaac ttgattcaca ggccgaacta    180

gtgagaattg cggcgagcag taagaagcag cgtgtggaaa agggagacga ttgttcatca    240

acatgagtat ggaccagaag aaaacctaga agatgacatg taccgtaaga cttgtactat    300

gtgtggccat gaactgacat atgaaaaaat gtgatttttt agttcagtga cctgttttat    360

agaattttat atttaaataa aggaaattta gattggtcct tttcaaaatt caaaaaaaaa    420

agcaacatct tcatagatga atgaaaccct tgtataagta atacttcagt aataattatg    480

tatgttatgg cttaaaagca agtttcagtg aaggtcacct ggcctggttg tgtgcacaat    540

gtcatgtctg tgattgcctt cttacaacag agatgggagc tgagtgctag agtaggtgca    600

gaagtggtag gtcagctaca aatttgagga caagatacca aggcaaaccc tagattgggg    660

tagagggaaa agggttcaac aaaggctgaa ctggattctt aaccaagaaa caaataatag    720

caatggtggt gcaccactgt accccaggtt ctagtcatgt gttttttagg acgatttctg    780

tctccacgat ggtggaaaca gtggggaact actgctggaa aaagccctaa tagcagaaat    840

aaacattgag ttgtacgagt ctga                                           864


<210>  6173
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  6173

Met Cys Pro Ile Val Leu Leu Asn Ser Leu Leu Asn Met Val Leu Phe 
1               5                   10                  15


Cys Ile Pro Pro Thr His Ile Thr Ile Ser Glu Ser Leu Val Ser His 
            20                  25                  30


Cys Ser Ser Asp Asn Leu Ile His Arg Pro Asn 
        35                  40


<210>  6174
<211>  746
<212>  DNA
<213>  Homo sapiens

<400>  6174
ggaggcttca ttttagaaga ggaagaagaa gaagaacaga aaattggaaa agttgttcat     60

caaccagaat tgcggcgagc agtaagaagc agcgtgtgga aaagggagac gattgttcat    120

caacatgagt atggaccaga agaaaaccta gaagatgaca tgtaccgtaa gacttgtact    180

atgtgtggcc atgaactgac atatgaaaaa atgtgatttt ttagttcagt gacctgtttt    240

atagaatttt atatttaaat aaaggaaatt tagattggtc cttttcaaaa ttcaaaaaaa    300

aaagcaacat cttcatagat gaatgaaacc cttgtataag taatacttca gtaataatta    360

tgtatgttat ggcttaaaag caagtttcag tgaaggtcac ctggcctggt tgtgtgcaca    420

atgtcatgtc tgtgattgcc ttcttacaac agagatggga gctgagtgct agagtaggtg    480

cagaagtggt aggtcagcta caaatttgag gacaagatac caaggcaaac cctagattgg    540

ggtagaggga aaagggttca acaaaggctg aactggattc ttaaccaaga aacaaataat    600

agcaatggtg gtgcaccact gtaccccagg ttctagtcat gtgtttttta ggacgatttc    660

tgtctccacg atggtggaaa cagtggggaa ctactgctgg aaaaagccct aatagcagaa    720

ataaacattg agttgtacga gtctga                                         746


<210>  6175
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  6175

Met Val Val His His Cys Thr Pro Gly Ser Ser His Val Phe Phe Arg 
1               5                   10                  15


Thr Ile Ser Val Ser Thr Met Val Glu Thr Val Gly Asn Tyr Cys Trp 
            20                  25                  30


Lys Lys Pro 
        35


<210>  6176
<211>  1700
<212>  DNA
<213>  Homo sapiens

<400>  6176
cactcagaaa ggccgctggg tgcggggagc gcagaggcgg tgcagggcgg ctggctcgcc     60

tcggcgtgca gtgcgcgtgc gtggagctgg gagctaggtc ctcggagtgg gccagagatg    120

gcggcggccg acggggcttt gccggaggcg gcggctttag agcaacccgc ggagctgcct    180

gcctcggtgc gggcgagtat cgagcggaag cggcagcggg cactgatgct gcgccaggcc    240

cggctggctg cccggcccta ctcggcgacg gcggctgcgg ctactggagg catggctaat    300

gtaaaagcag ccccaaagat aattgacaca ggaggaggct tcattttaga agaggaagaa    360

gaagaagaac agaaaattgg aaaagttgtt catcaaccag gacctgttat ggaatttgat    420

tatgtaatat gcgaagaatg tgggaaagaa tttatggatt cttatcttat gaaccacttt    480

gatttgccaa cttgtgataa ctgcagagat gctgatgata aacacaagct tataaccaaa    540

acagaggcaa aacaagaata tcttctgaaa gactgtgatt tagaaaaaag agagccacct    600

cttaaattta ttgtgaagaa gaatccacat cattcacaat ggggtgatat gaaactctac    660

ttaaagttac agattgtgaa gaggtctctt gaagtttggg gtagtcaaga agcattagaa    720

gaagcaaagg aagtccgaca ggaaaaccga gaaaaaatga aacagaagaa atttgataaa    780

aaagtaaaag aggttgttcc cgccttcctg aataggccac aaagggctga gactggagta    840

gacactgtag agattagaca caaggagctt actgtgcagt tttctcagaa ggctcagaac    900

agagaggaat aaaagcaagt ctaaaagtat tttagttgaa aagaaattgg aacctggttc    960

ctcttggtct tctgattttg atccacaaag aagctgacac agtttacttc tttatgggaa   1020

gaattgcggc gagcagtaag aagcagcgtg tggaaaaggg agacgattgt tcatcaacat   1080

gagtatggac cagaagaaaa cctagaagat gacatgtacc gtaagacttg tactatgtgt   1140

ggccatgaac tgacatatga aaaaatgtga ttttttagtt cagtgacctg ttttatagaa   1200

ttttatattt aaataaagga aatttagatt ggtccttttc aaaattcaaa aaaaaaagca   1260

acatcttcat agatgaatga aacccttgta taagtaatac ttcagtaata attatgtatg   1320

ttatggctta aaagcaagtt tcagtgaagg tcacctggcc tggttgtgtg cacaatgtca   1380

tgtctgtgat tgccttctta caacagagat gggagctgag tgctagagta ggtgcagaag   1440

tggtaggtca gctacaaatt tgaggacaag ataccaaggc aaaccctaga ttggggtaga   1500

gggaaaaggg ttcaacaaag gctgaactgg attcttaacc aagaaacaaa taatagcaat   1560

ggtggtgcac cactgtaccc caggttctag tcatgtgttt tttaggacga tttctgtctc   1620

cacgatggtg gaaacagtgg ggaactactg ctggaaaaag ccctaatagc agaaataaac   1680

attgagttgt acgagtctga                                               1700


<210>  6177
<211>  264
<212>  PRT
<213>  Homo sapiens

<400>  6177

Met Ala Ala Ala Asp Gly Ala Leu Pro Glu Ala Ala Ala Leu Glu Gln 
1               5                   10                  15


Pro Ala Glu Leu Pro Ala Ser Val Arg Ala Ser Ile Glu Arg Lys Arg 
            20                  25                  30


Gln Arg Ala Leu Met Leu Arg Gln Ala Arg Leu Ala Ala Arg Pro Tyr 
        35                  40                  45


Ser Ala Thr Ala Ala Ala Ala Thr Gly Gly Met Ala Asn Val Lys Ala 
    50                  55                  60


Ala Pro Lys Ile Ile Asp Thr Gly Gly Gly Phe Ile Leu Glu Glu Glu 
65                  70                  75                  80


Glu Glu Glu Glu Gln Lys Ile Gly Lys Val Val His Gln Pro Gly Pro 
                85                  90                  95


Val Met Glu Phe Asp Tyr Val Ile Cys Glu Glu Cys Gly Lys Glu Phe 
            100                 105                 110


Met Asp Ser Tyr Leu Met Asn His Phe Asp Leu Pro Thr Cys Asp Asn 
        115                 120                 125


Cys Arg Asp Ala Asp Asp Lys His Lys Leu Ile Thr Lys Thr Glu Ala 
    130                 135                 140


Lys Gln Glu Tyr Leu Leu Lys Asp Cys Asp Leu Glu Lys Arg Glu Pro 
145                 150                 155                 160


Pro Leu Lys Phe Ile Val Lys Lys Asn Pro His His Ser Gln Trp Gly 
                165                 170                 175


Asp Met Lys Leu Tyr Leu Lys Leu Gln Ile Val Lys Arg Ser Leu Glu 
            180                 185                 190


Val Trp Gly Ser Gln Glu Ala Leu Glu Glu Ala Lys Glu Val Arg Gln 
        195                 200                 205


Glu Asn Arg Glu Lys Met Lys Gln Lys Lys Phe Asp Lys Lys Val Lys 
    210                 215                 220


Glu Val Val Pro Ala Phe Leu Asn Arg Pro Gln Arg Ala Glu Thr Gly 
225                 230                 235                 240


Val Asp Thr Val Glu Ile Arg His Lys Glu Leu Thr Val Gln Phe Ser 
                245                 250                 255


Gln Lys Ala Gln Asn Arg Glu Glu 
            260


<210>  6178
<211>  1469
<212>  DNA
<213>  Homo sapiens

<400>  6178
cactcagaaa ggccgctggg tgcggggagc gcagaggcgg tgcagggcgg ctggctcgcc     60

tcggcgtgca gtgcgcgtgc gtggagctgg gagctaggtc ctcggagtgg gccagagatg    120

gcggcggccg acggggcttt gccggaggcg gcggctttag agcaacccgc ggagctgcct    180

gcctcggtgc gggcgagtat cgagcggaag cggcagcggg cactgatgct gcgccaggcc    240

cggctggctg cccggcccta ctcggcgacg gcggctgcgg ctactggagg catggctaat    300

gtaaaagcag ccccaaagat aattgacaca ggaggaggct tcattttaga agaggaagaa    360

gaagaagaac agaaaattgg aaaagttgtt catcaaccag gacctgttat ggaatttgat    420

tatgtaatat gcgaagaatg tgggaaagaa tttatggatt cttatcttat gaaccacttt    480

gatttgccaa cttgtgataa ctgcagagat gctgatgata aacacaagct tataaccaaa    540

acagaggcaa aacaagaata tcttctgaaa gactgtgatt tagaaaaaag agagccacct    600

cttaaattta ttgtgaagaa gaatccacat cattcacaat ggggtgatat gaaactctac    660

ttaaagttac agattgtgaa gaggtctctt gaagtttggg gtagtcaaga agcattagaa    720

gaagcaaagg aagtccgaca ggaaaaccga gaaaaaatga aacagaagaa atttgataaa    780

aaagtaaaag aattgcggcg agcagtaaga agcagcgtgt ggaaaaggga gacgattgtt    840

catcaacatg agtatggacc agaagaaaac ctagaagatg acatgtaccg taagacttgt    900

actatgtgtg gccatgaact gacatatgaa aaaatgtgat tttttagttc agtgacctgt    960

tttatagaat tttatattta aataaaggaa atttagattg gtccttttca aaattcaaaa   1020

aaaaaagcaa catcttcata gatgaatgaa acccttgtat aagtaatact tcagtaataa   1080

ttatgtatgt tatggcttaa aagcaagttt cagtgaaggt cacctggcct ggttgtgtgc   1140

acaatgtcat gtctgtgatt gccttcttac aacagagatg ggagctgagt gctagagtag   1200

gtgcagaagt ggtaggtcag ctacaaattt gaggacaaga taccaaggca aaccctagat   1260

tggggtagag ggaaaagggt tcaacaaagg ctgaactgga ttcttaacca agaaacaaat   1320

aatagcaatg gtggtgcacc actgtacccc aggttctagt catgtgtttt ttaggacgat   1380

ttctgtctcc acgatggtgg aaacagtggg gaactactgc tggaaaaagc cctaatagca   1440

gaaataaaca ttgagttgta cgagtctga                                     1469


<210>  6179
<211>  273
<212>  PRT
<213>  Homo sapiens

<400>  6179

Met Ala Ala Ala Asp Gly Ala Leu Pro Glu Ala Ala Ala Leu Glu Gln 
1               5                   10                  15


Pro Ala Glu Leu Pro Ala Ser Val Arg Ala Ser Ile Glu Arg Lys Arg 
            20                  25                  30


Gln Arg Ala Leu Met Leu Arg Gln Ala Arg Leu Ala Ala Arg Pro Tyr 
        35                  40                  45


Ser Ala Thr Ala Ala Ala Ala Thr Gly Gly Met Ala Asn Val Lys Ala 
    50                  55                  60


Ala Pro Lys Ile Ile Asp Thr Gly Gly Gly Phe Ile Leu Glu Glu Glu 
65                  70                  75                  80


Glu Glu Glu Glu Gln Lys Ile Gly Lys Val Val His Gln Pro Gly Pro 
                85                  90                  95


Val Met Glu Phe Asp Tyr Val Ile Cys Glu Glu Cys Gly Lys Glu Phe 
            100                 105                 110


Met Asp Ser Tyr Leu Met Asn His Phe Asp Leu Pro Thr Cys Asp Asn 
        115                 120                 125


Cys Arg Asp Ala Asp Asp Lys His Lys Leu Ile Thr Lys Thr Glu Ala 
    130                 135                 140


Lys Gln Glu Tyr Leu Leu Lys Asp Cys Asp Leu Glu Lys Arg Glu Pro 
145                 150                 155                 160


Pro Leu Lys Phe Ile Val Lys Lys Asn Pro His His Ser Gln Trp Gly 
                165                 170                 175


Asp Met Lys Leu Tyr Leu Lys Leu Gln Ile Val Lys Arg Ser Leu Glu 
            180                 185                 190


Val Trp Gly Ser Gln Glu Ala Leu Glu Glu Ala Lys Glu Val Arg Gln 
        195                 200                 205


Glu Asn Arg Glu Lys Met Lys Gln Lys Lys Phe Asp Lys Lys Val Lys 
    210                 215                 220


Glu Leu Arg Arg Ala Val Arg Ser Ser Val Trp Lys Arg Glu Thr Ile 
225                 230                 235                 240


Val His Gln His Glu Tyr Gly Pro Glu Glu Asn Leu Glu Asp Asp Met 
                245                 250                 255


Tyr Arg Lys Thr Cys Thr Met Cys Gly His Glu Leu Thr Tyr Glu Lys 
            260                 265                 270


Met 



<210>  6180
<211>  1016
<212>  DNA
<213>  Homo sapiens

<400>  6180
cactcagaaa ggccgctggg tgcggggagc gcagaggcgg tgcagggcgg ctggctcgcc     60

tcggcgtgca gtgcgcgtgc gtggagctgg gagctaggtc ctcggagtgg gccagagatg    120

gcggcggccg acggggcttt gccggaggcg gcggctttag agcaacccgc ggagctgcct    180

gcctcggtgc gggcgagtat cgagcggaag cggcagcggg cactgatgct gcgccaggcc    240

cggctggctg cccggcccta ctcggcgacg gcggctgcgg ctactggagg catggctaat    300

gtaaaagcag ccccaaagat aattgacaca ggaggaggct tcattttaga agaggaagaa    360

gaagaagaac agaaaattgg aaaagttgtt catcaaccag gacctgttat ggaatttgat    420

tatgtaatat gcgaagaatg tgggaaagaa tttatggatt cttatcttat gaaccacttt    480

gatttgccaa cttgtgataa ctgcagagat gctgatgata aacacaagct tataaccaaa    540

acagaggcaa aacaagaata tcttctgaaa gactgtgatt tagaaaaaag agagccacct    600

cttaaattta ttgtgaagaa gaatccacat cattcacaat ggggtgatat gaaactctac    660

ttaaagttac agattgtgaa gaggtctctt gaagtttggg gtagtcaaga agcattagaa    720

gaagcaaagg aagtccgaca ggaaaaccga gaaaaaatga aacagaagaa atttgataaa    780

aaagtaaaag aattgcggcg agcagtaaga agcagcgtgt ggaaaaggga gacgattgtt    840

catcaacatg agtatggacc agaagaaaac ctagaagatg acatgtaccg taagacttgt    900

actatgtgtg gccatgaact gacatatgaa aaaatgtgat tttttagttc agtgacctgt    960

tttatagaat tttatattta aataaaggaa atttagattg gtccttttca aaattc       1016


<210>  6181
<211>  273
<212>  PRT
<213>  Homo sapiens

<400>  6181

Met Ala Ala Ala Asp Gly Ala Leu Pro Glu Ala Ala Ala Leu Glu Gln 
1               5                   10                  15


Pro Ala Glu Leu Pro Ala Ser Val Arg Ala Ser Ile Glu Arg Lys Arg 
            20                  25                  30


Gln Arg Ala Leu Met Leu Arg Gln Ala Arg Leu Ala Ala Arg Pro Tyr 
        35                  40                  45


Ser Ala Thr Ala Ala Ala Ala Thr Gly Gly Met Ala Asn Val Lys Ala 
    50                  55                  60


Ala Pro Lys Ile Ile Asp Thr Gly Gly Gly Phe Ile Leu Glu Glu Glu 
65                  70                  75                  80


Glu Glu Glu Glu Gln Lys Ile Gly Lys Val Val His Gln Pro Gly Pro 
                85                  90                  95


Val Met Glu Phe Asp Tyr Val Ile Cys Glu Glu Cys Gly Lys Glu Phe 
            100                 105                 110


Met Asp Ser Tyr Leu Met Asn His Phe Asp Leu Pro Thr Cys Asp Asn 
        115                 120                 125


Cys Arg Asp Ala Asp Asp Lys His Lys Leu Ile Thr Lys Thr Glu Ala 
    130                 135                 140


Lys Gln Glu Tyr Leu Leu Lys Asp Cys Asp Leu Glu Lys Arg Glu Pro 
145                 150                 155                 160


Pro Leu Lys Phe Ile Val Lys Lys Asn Pro His His Ser Gln Trp Gly 
                165                 170                 175


Asp Met Lys Leu Tyr Leu Lys Leu Gln Ile Val Lys Arg Ser Leu Glu 
            180                 185                 190


Val Trp Gly Ser Gln Glu Ala Leu Glu Glu Ala Lys Glu Val Arg Gln 
        195                 200                 205


Glu Asn Arg Glu Lys Met Lys Gln Lys Lys Phe Asp Lys Lys Val Lys 
    210                 215                 220


Glu Leu Arg Arg Ala Val Arg Ser Ser Val Trp Lys Arg Glu Thr Ile 
225                 230                 235                 240


Val His Gln His Glu Tyr Gly Pro Glu Glu Asn Leu Glu Asp Asp Met 
                245                 250                 255


Tyr Arg Lys Thr Cys Thr Met Cys Gly His Glu Leu Thr Tyr Glu Lys 
            260                 265                 270


Met 



<210>  6182
<211>  932
<212>  DNA
<213>  Homo sapiens

<400>  6182
tggctcgcct cggcgtgcag tgcgcgtgcg tggagctggg agctaggtcc tcggagtggg     60

ccagagatgg cggcggccga cggggctttg ccggaggcgg cggctttaga gcaacccgcg    120

gagctgcctg cctcggtgcg ggcgagtatc gagcggaagc ggcagcgggc actgatgctg    180

cgccaggccc ggctggctgc ccggccctac tcggcgacgg cggctgcggc tactggaggc    240

atggctaatg taaaagcagc cccaaagata attgacacag gaggaggctt cattttagaa    300

gaggaagaag aagaagaaca gaaaattgga aaagttgttc atcaaccagg taaagtgagt    360

ttttcaaaaa taagtatcta gattggttat tttgagtaac atgcataatt ctatgcaaag    420

tgatgctaaa taatgccata actactttaa tcagtgagta cattatcttt ataaaagtga    480

taaagtttgg cagttttgct agtagattaa aaaaacaatc aaagaaacag ccatgcatat    540

ggaaatgatt atttaacttg tggctgatgt acttaggggt tgctgctctc tgttgtttta    600

taataggcag ggttagccag tatattgatt ggtagaataa atactcaaaa ttatcttgat    660

aggctgaaat gaggcaccag aatccaagag ataacattta ggacattctt ttatttatct    720

gtggagaaag aaagcagctt acaaagtata agatagacca gcataaaaag aaggatgtaa    780

ctatgatcta aggttagtgc tttggtaaat cacttatatg tacacatatc ttcacagtga    840

gggtactttc acactctttg ggaaaaagat agaaacactt tatttgttca taagtttggc    900

agccaacagt gcaatataac agctttttat ta                                  932


<210>  6183
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  6183

Met Ala Ala Ala Asp Gly Ala Leu Pro Glu Ala Ala Ala Leu Glu Gln 
1               5                   10                  15


Pro Ala Glu Leu Pro Ala Ser Val Arg Ala Ser Ile Glu Arg Lys Arg 
            20                  25                  30


Gln Arg Ala Leu Met Leu Arg Gln Ala Arg Leu Ala Ala Arg Pro Tyr 
        35                  40                  45


Ser Ala Thr Ala Ala Ala Ala Thr Gly Gly Met Ala Asn Val Lys Ala 
    50                  55                  60


Ala Pro Lys Ile Ile Asp Thr Gly Gly Gly Phe Ile Leu Glu Glu Glu 
65                  70                  75                  80


Glu Glu Glu Glu Gln Lys Ile Gly Lys Val Val His Gln Pro Gly Lys 
                85                  90                  95


Val Ser Phe Ser Lys Ile Ser Ile 
            100


<210>  6184
<211>  370
<212>  DNA
<213>  Homo sapiens

<400>  6184
tcttccatct ccacacagcc aaagatagct gaacttttgt ttgacatttt acacggtgtc     60

ttatacctgc ctgaaagaag gggtgcaggt cttcacagaa tgaggaaagg ccagagattt    120

ggactccaaa gaccacagct tggattctaa gctgtcactt accagccaaa agggaatctt    180

ggcccagtca ctgaagcccc ctgagtctca actacctcat ctgtaaaggg tctcatcagg    240

cccacattag attatctact cgaccatcag ttcaagctct aaggtaaaga tgtagagcaa    300

ctggaacttt catacactgc tgcaaccact ttggagacta tcagcatttt ccactaaagc    360

tgaacattat                                                           370


<210>  6185
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  6185

Ser Pro Leu Ser Leu Asn Tyr Leu Ile Cys Lys Gly Ser His Gln Ala 
1               5                   10                  15


His Ile Arg Leu Ser Thr Arg Pro Ser Val Gln Ala Leu Arg 
            20                  25                  30


<210>  6186
<211>  8674
<212>  DNA
<213>  Homo sapiens

<400>  6186
ggagagggag ggagggagag agagagagag ggagagagac ggatatctca ggtcatctgc     60

agctgcagcg agtctgagga gccgaggaag gcagggaaga tggcgatcct ccattgctga    120

gacccggcag aagcacatga gactcccaaa caacttccac aacaataacc cgagcaggaa    180

gaggagaaag agaaagagga taaggaggcg gtggggctgg agaacccgaa gcacctcccg    240

gcgccgggac gcttcttctg ttcctaatgt gagaggctag acccagatca tggaggtgct    300

tcagtgtgat ggctgtgatt tccgagcccc gtcttatgaa gatctcaagg cacacattca    360

ggatgtccac acggcatttc tgcagccaac tgatgttgct gaggacaatg tgaatgagct    420

acgatgtggg tccgtgaatg ccagtaatca gacagaggtg gagttttctt ctataaagga    480

tgaatttgcc attgcagaag atttatcagg tcaaaatgca acttcattgg ggaccggagg    540

ttactatggc cacagtccag gatattatgg tcagcatatt gccgctaatc ccaaaccaac    600

aaacaagttt tttcaatgca agttctgtgt acgctacttc aggtcaaaaa acctcctcat    660

agaacacact agaaaggtcc atggagctca agctgaaggg agttcatcag gaccccctgt    720

cccgggatcc ttaaattata atatcatgat gcacgaggga tttggaaagg tcttctcttg    780

ccagttttgc acatacaagt caccaagaag ggcaagaata attaagcatc agaagatgta    840

tcacaaaaac aatttgaagg agaccactgc tcccccacct gctcctgctc caatgccaga    900

ccctgtggtt ccgcccgtat cactgcagga cccctgcaag gaactgccag cagaggttgt    960

ggagcgcagc atcttagagt ctatggtcaa gcctttgacc aaatctcgag gcaacttttg   1020

ttgtgagtgg tgcagctacc agaccccccg ccgagaacgc tggtgtgacc acatgatgaa   1080

gaaacaccgc agtatggtca agatcctttc cagtctcaga cagcaacaag aaggaactaa   1140

tctacctgat gtgccgaaca agagtgcccc cagccccact tccaactcca cctatctgac   1200

catgaatgct gcaagccggg agatacccaa tactaccgtc tccaacttca ggggctccat   1260

gggcaactcc atcatgagac ccaattcttc agcttccaag ttttcgccca tgtcttaccc   1320

tcagatgaag ccgaagtcac ctcacaattc tggtctagtt aacttgacag agagatcccg   1380

ttatggaatg actgacatga ccaattcttc tgctgacctg gaaactaaca gcatgctaaa   1440

tgactctagt tctgatgaag agttaaatga aatagacagt gagaatggtt taagtgctat   1500

ggatcaccag acatcaggcc tgtctgcaga gcagctgatg ggctcagatg gcaacaaatt   1560

attggagacc aaggggattc catttagaag attcatgaat aggttccagt gccccttttg   1620

tcctttcctc accatgcatc gacgtagcat ctctcgtcac atagaaaaca tccacttatc   1680

tggaaagaca gctgtctaca aatgtgacga atgtccgttt acttgcaaga gctcgttgaa   1740

acttggggct cacaaacagt gtcacacggg tacaacgtca gattgggatg ctgtgaattc   1800

ccagagtgaa agcatttctt cctcactgaa tgaaggtgtg gtgtcttatg agagctcaag   1860

catcaatggt agaaagtcag gagtcatgtt ggatcccttg cagcagcaac agccaccgca   1920

gccaccacca ccgccgccgc caccaccacc atcacagcca cagccactgc agcagccaca   1980

gccaccacag ctgcagccac cacatcaggt gccaccccag ccacaaacac agccaccacc   2040

aacgcagcag ccacagccac ccacacaagc cgcacctctg cacccataca aatgcaccat   2100

gtgtaattac tccaccacaa ctctgaaagg gctaagagtc catcagcagc ataaacattc   2160

attctgtgac aacttgccaa aattcgaggg gcagccctca agcctaccat tggaaaatga   2220

gacagacagc cacccctctt ccagcaacac tgtgaagaaa agtcagacct caattcttgg   2280

gttgtcctcc aagaacaatt ttgtagctaa agcctctagg aagctcgcca atgactttcc   2340

tctagatttg tcacccgtga agaagagaac caggattgac gagatagcaa gcaaccttca   2400

gagcaaaatt aaccaaacca aacagcagga agatgcagtg atcaatgttg aggatgatga   2460

agaggaagag gaagacaacg aagtcgagat agaggttgag ttggacaggg aggaagaacc   2520

gacagaaccc atcatagagg ttcccacttc cttttctgcc caacagatat gggtaagaga   2580

taccagtgag ccccagaaag agcccaactt cagaaacatc acccacgatt acaatgccac   2640

caatggggct gagattgagc tcaccctttc tgaagatgaa gaggattatt atggctcctc   2700

aacaaacttg aaagatcacc aagtttccaa tactgctctg ctgaataccc aaactcccat   2760

ctatgggact gagcacaata gtgaaaacac agactttggt gactctggaa ggctttacta   2820

ttgtaaacac tgtgacttta acaacaaatc tgcccggagt gttagcaccc actaccaacg   2880

aatgcaccca tacattaaat tcagctttag gtacatcttg gaccccaatg atcacagtgc   2940

agtgtacagg tgcctggaat gctacatcga ttacaccaac ttcgaagatc tccagcagca   3000

ttatggcgag caccacccag aagccatgaa tgtactcaac tttgatcact cggacctgat   3060

ctaccggtgt cggttttgtt catacacgag cccgaatgtt agaagcctga tgccacatta   3120

ccaaagaatg catcccacgg tgaagatcaa caacgcgatg atattttcaa gctatgtcgt   3180

ggagcagcag gaagggctga atacagaatc ccagaccctg agggagattc tgaattcggc   3240

tcccaagaac atggcgactt ccacacctgt ggctcgtggt ggtggtttgc cagctacgtt   3300

caacaaaaac actcctaaga cctttactcc tgaatgtgaa aatcagaagg accctttggt   3360

caacactgtt gttgtttatg attgtgatgt ttgttcgttt gcaagcccca acatgcattc   3420

tgtcttggtt cattatcaga agaaacaccc cgaagaaaag gcttcctact ttaggatcca   3480

gaaaactatg cgaatggtgt ctgtggacag gggctctgcc ctttctcaat tatcatttga   3540

ggtgggtgct ccaatgtctc ccaaaatgtc caacatgggt tccccacccc ccccacaacc   3600

cccgccacca gacctcagta ctgagcttta ctactgcaaa cactgttcct acagcaatcg   3660

gtcagttgtg ggagtgcttg tccactacca gaaaagacac ccagaaataa aggttactgc   3720

caaatatatc agacaggctc ctcccacagc tgcaatgatg agaggggtcg aagggcccca   3780

aggctccccc cggccacccg cccccataca acagctgaac cgaagcagct ctgagagaga   3840

tggccctcct gtggagaatg agatgttctt ttgccagcac tgtgattatg ggaaccggac   3900

ggtcaaaggg gtactcattc attatcagaa gaagcaccga gacttcaagg ccaatgcaga   3960

tgtgatccgg cagcatacgg ccaccattcg aagcctctgc gaccgaaatc agaagaagcc   4020

tgccagctgc gtgcttgtct ccccctctaa tctggagcgg gacaaaacga aactccgagc   4080

actcaaatgt aggcagtgct catatacctc cccctacttc tatgcactga ggaagcatat   4140

caagaaagac caccccgccc tgaaagccac agtcacgtcc atcatgcgat gggcatttct   4200

agatggcttg atagaagctg gctaccactg cgagtggtgc atctactccc atacggagcc   4260

caacggtttg ctcctgcatt accaacggag gcatccagaa cactatgttg attacaccta   4320

catggctact aaactgtggg ctgggccaga cccatcccct ccctctctca caatgccagc   4380

cgaagccaaa acctacagat gcagggactg tgttttcgaa gctgtttcca tctgggacat   4440

cactaatcac taccaagcat tccacccctg ggccatgaat ggtgatgagt cagtgctact   4500

ggacatcatc aaggagaaag atgctgtgga gaagcccatt ctttcatccg aagagttggc   4560

aggccctgtg aattgtgaaa acagtatacc cacccctttc ccggagcagg aagctgaatg   4620

tccagaggat gcaagactgt cccctgagaa aagcctgcag ctagcttcag ccaaccccgc   4680

catatcctcc accccatacc agtgcacggt atgccaatct gagtataaca acttgcacgg   4740

ccttctcact cattatggga agaagcaccc tggcatgaaa gtgaaggctg ctgactttgc   4800

ccaggacatt gacatcaacc caggtgccgt ctacaaatgc aggcattgcc catacatcaa   4860

cacccgcatc cacggcgtac tgacccacta ccagaagcga cacccgtcca tcaaggtgac   4920

cgctgaggac tttgtgcacg acgtagagca gtctgctgac atatcccaga atgacgtgga   4980

ggagacgagc aggatcttca agcaagggta tggcgcctac cggtgcaaac tgtgtccgta   5040

cacacacggc actttggaga aactaaaaat ccactacgag aagtatcaca atcagcctga   5100

atttgatgtc ttttcccagt cgcccccgaa gctgccagtc cccctcgagc ccgagatgac   5160

cactgaagtg agcccttccc aagtctccat cactgaggag gaggtgggag aggagcccgt   5220

gtccacttct cacttctcta cctcccacct ggtctcccac actgtgttcc ggtgccagct   5280

ctgcaagtac ttctgctcca cgaggaaggg gatcgccagg cactaccgca tcaagcacaa   5340

taatgtccga gcccagccag aaggcaagaa caacctcttc aagtgtgccc tgtgtgccta   5400

caccaacccc atccgcaaag gtctggcagc ccactaccag aagcgccacg acattgatgc   5460

gtattacact cactgcttgg cagcctccag gaccatcagc gacaagccca acaaagtgat   5520

catcccatcc ccgcccaagg acgactcccc tcagctgagc gaggaactcc ggcgggcagt   5580

ggagaagaaa aagtgctcct tgtgctcttt ccagtcgttc agcaagaagg gcatcgtgtc   5640

ccattacatg aaacgccacc caggggtgtt cccaaagaag cagcacgcca gcaagttggg   5700

gggctacttc acggccgtct atgcagatga gcatgagaag cccacactga tggaagaaga   5760

ggagagaggc aactttgaga aagccgaggt ggagggtgaa gctcaggaaa tcgagtggct   5820

cccattccgc tgcatcaaat gcttcaagct gtcctttagc actgcagagc tgctgtgcat   5880

gcattacact gaccaccaca gtcgggacct aaagagggac ttcatcattc tgggcaacgg   5940

cccccgcttg cagaactcca cctaccagtg taagcactgt gatagcaaac tgcaaagcac   6000

agccgagctg acctcacact tgaacattca caatgaggaa ttccagaagc gtgccaaacg   6060

tcaggagagg aggaaacagc ttttgagcaa gcagaaatat gcagatggtg cttttgcaga   6120

tttcaaacaa gagaggcctt ttggtcactt agaagaggtg ccaaagatca aggagaggaa   6180

agtggtgggc tacaaatgta aattctgtgt ggaagtgcac ccaacgctcc gagccatctg   6240

caatcacctc cgaaagcacg tccagtatgg caatgtccca gctgtgtcag ctgctgtgaa   6300

ggggctgcgt tctcatgaga ggagccacct ggccctggcc atgtttaccc gcgaggacaa   6360

gtacagctgc cagtattgct cgtttgtttc tgctttcagg cacaatttgg atcgccatat   6420

gcaaacccac cacggacacc ataaaccatt ccgatgcaaa ctctgctcct tcaagtcctc   6480

ctataacagc cggctgaaaa cacatatact caaagctcat gctggtgagc atgcctacaa   6540

gtgttcttgg tgctcattct ccaccatgac aatcagccag ctgaaggaac actccctcaa   6600

ggtccacgga aaagccctga ccctccccag gccacggatc gtcagtctcc tctcctcaca   6660

ctcccaccac tcctcccaaa aagctacccc ggctgaagaa gtggaagact ccaatgactc   6720

atcatattca gagcccccag atgttcagca gcagttgaac cactatcagt cagctgccct   6780

ggcaaggaac aacagccgtg ttagccctgt gcctctttct ggggctgctg ctggcactga   6840

gcagaaaact gaagccgtgc ttcactgcga attctgtgaa ttctcctccg gctacatcca   6900

gagcatcagg cgtcattacc gggacaagca tggtgggaag aagcttttca agtgcaaaga   6960

ctgctccttt tacacaggct ttaaatctgc ttttactatg cacgtggaag ctgggcactc   7020

agcagttccc gaggagggcc ccaaagatct tcgctgtcct ctctgcctct atcacaccaa   7080

atacaagcgc aacatgattg accacatcgt gctgcaccga gaagagcgtg ttgtccccat   7140

tgaagtttgc cggtccaaac tgtccaaata cttgcaggga gtagttttcc gctgtgataa   7200

gtgtaccttc acctgctcca gtgatgagag cctccagcaa catatagaaa agcacaatga   7260

actgaaacct tacaaatgcc agctctgcta ctatgagacc aagcacacgg aggaactgga   7320

cagccacctt cgggatgagc ataaggtaag ccgtaacttt gagctggttg gacgggttaa   7380

cttggatcag ctggaacaga tgaaggagaa aatggagagc tccagcagcg atgatgagga   7440

caaggaagaa gaaatgaaca gcaaggctga agacagagag ctgatgagat tttctgacca   7500

cggggctgct cttaacactg agaagcgttt tccatgtgaa ttttgtggac gggcgttttc   7560

acagggctct gagtgggaaa gacatgtgct gagacacggc atggcattga atgacaccaa   7620

gcaggtgagc agagaagaaa tccacccaaa agagatcatg gagaacagtg ttaaaatgcc   7680

ctccatagag gaaaaggaag atgacgaggc cattgggata gacttttccc taaagaatga   7740

aacagtagcc atctgtgtag taactgccga caaatctctc ctggagaatg cagaggccaa   7800

aaaagaatga gcgtttggtg aaattcttaa tcaaacctta cttgaacagt gatgaaaaag   7860

tgggagggct ggcttgggct gagaagggag ggacagaaaa gagaagacag aacaaagctg   7920

ctttttagga ctgaacaatc tattttcaaa gcactggtac ctgtgtgagt gagtatgtaa   7980

attaaagtta tttaaatggt tggaatatgt ggctcctttt ccatcactac atcttttctt   8040

ccggatcttc atcatggaag tttcatttgt tgcggaatat ggaagcacct cccaatggta   8100

cggtgcaccc tgtggtggtc ttggacagta tgtggaaaca gaagctccat gacggtagaa   8160

gacttctcat tggggagcaa ctttttgacg cacaactttt ggtgcgtttt tctagtttta   8220

ataccttaag ctttttcaag acctaactgc agccgctttg ggaaaaaaaa acaaaaaaca   8280

aaaaacagaa aacaaaaaaa aaaaaactgc tttgcataaa acagtcacct gtttcctagt   8340

acctcaaact taaccaaggg aactctctgc atttgtcagt actacctgtc gtcgttgtgg   8400

ttaaatgtag agagaactgc tgggcaagat ggtgaatgga gaaaaaaaaa gagttttaaa   8460

gaaaggaaca caaattgtgc ttaaaatccc catgtgggtt ttatttctta aaatactgtg   8520

atttttttaa ttattttagt aaaaaacaaa acaaaaaaaa gaaacagact ttaattatta   8580

gataactgtt tgtgaattgt catcctttat tccaggtaag ctgtttatta gtgttcaact   8640

ataatttaga atttggtaga ttcatgtgag ctaa                               8674


<210>  6187
<211>  2506
<212>  PRT
<213>  Homo sapiens

<400>  6187

Met Glu Val Leu Gln Cys Asp Gly Cys Asp Phe Arg Ala Pro Ser Tyr 
1               5                   10                  15


Glu Asp Leu Lys Ala His Ile Gln Asp Val His Thr Ala Phe Leu Gln 
            20                  25                  30


Pro Thr Asp Val Ala Glu Asp Asn Val Asn Glu Leu Arg Cys Gly Ser 
        35                  40                  45


Val Asn Ala Ser Asn Gln Thr Glu Val Glu Phe Ser Ser Ile Lys Asp 
    50                  55                  60


Glu Phe Ala Ile Ala Glu Asp Leu Ser Gly Gln Asn Ala Thr Ser Leu 
65                  70                  75                  80


Gly Thr Gly Gly Tyr Tyr Gly His Ser Pro Gly Tyr Tyr Gly Gln His 
                85                  90                  95


Ile Ala Ala Asn Pro Lys Pro Thr Asn Lys Phe Phe Gln Cys Lys Phe 
            100                 105                 110


Cys Val Arg Tyr Phe Arg Ser Lys Asn Leu Leu Ile Glu His Thr Arg 
        115                 120                 125


Lys Val His Gly Ala Gln Ala Glu Gly Ser Ser Ser Gly Pro Pro Val 
    130                 135                 140


Pro Gly Ser Leu Asn Tyr Asn Ile Met Met His Glu Gly Phe Gly Lys 
145                 150                 155                 160


Val Phe Ser Cys Gln Phe Cys Thr Tyr Lys Ser Pro Arg Arg Ala Arg 
                165                 170                 175


Ile Ile Lys His Gln Lys Met Tyr His Lys Asn Asn Leu Lys Glu Thr 
            180                 185                 190


Thr Ala Pro Pro Pro Ala Pro Ala Pro Met Pro Asp Pro Val Val Pro 
        195                 200                 205


Pro Val Ser Leu Gln Asp Pro Cys Lys Glu Leu Pro Ala Glu Val Val 
    210                 215                 220


Glu Arg Ser Ile Leu Glu Ser Met Val Lys Pro Leu Thr Lys Ser Arg 
225                 230                 235                 240


Gly Asn Phe Cys Cys Glu Trp Cys Ser Tyr Gln Thr Pro Arg Arg Glu 
                245                 250                 255


Arg Trp Cys Asp His Met Met Lys Lys His Arg Ser Met Val Lys Ile 
            260                 265                 270


Leu Ser Ser Leu Arg Gln Gln Gln Glu Gly Thr Asn Leu Pro Asp Val 
        275                 280                 285


Pro Asn Lys Ser Ala Pro Ser Pro Thr Ser Asn Ser Thr Tyr Leu Thr 
    290                 295                 300


Met Asn Ala Ala Ser Arg Glu Ile Pro Asn Thr Thr Val Ser Asn Phe 
305                 310                 315                 320


Arg Gly Ser Met Gly Asn Ser Ile Met Arg Pro Asn Ser Ser Ala Ser 
                325                 330                 335


Lys Phe Ser Pro Met Ser Tyr Pro Gln Met Lys Pro Lys Ser Pro His 
            340                 345                 350


Asn Ser Gly Leu Val Asn Leu Thr Glu Arg Ser Arg Tyr Gly Met Thr 
        355                 360                 365


Asp Met Thr Asn Ser Ser Ala Asp Leu Glu Thr Asn Ser Met Leu Asn 
    370                 375                 380


Asp Ser Ser Ser Asp Glu Glu Leu Asn Glu Ile Asp Ser Glu Asn Gly 
385                 390                 395                 400


Leu Ser Ala Met Asp His Gln Thr Ser Gly Leu Ser Ala Glu Gln Leu 
                405                 410                 415


Met Gly Ser Asp Gly Asn Lys Leu Leu Glu Thr Lys Gly Ile Pro Phe 
            420                 425                 430


Arg Arg Phe Met Asn Arg Phe Gln Cys Pro Phe Cys Pro Phe Leu Thr 
        435                 440                 445


Met His Arg Arg Ser Ile Ser Arg His Ile Glu Asn Ile His Leu Ser 
    450                 455                 460


Gly Lys Thr Ala Val Tyr Lys Cys Asp Glu Cys Pro Phe Thr Cys Lys 
465                 470                 475                 480


Ser Ser Leu Lys Leu Gly Ala His Lys Gln Cys His Thr Gly Thr Thr 
                485                 490                 495


Ser Asp Trp Asp Ala Val Asn Ser Gln Ser Glu Ser Ile Ser Ser Ser 
            500                 505                 510


Leu Asn Glu Gly Val Val Ser Tyr Glu Ser Ser Ser Ile Asn Gly Arg 
        515                 520                 525


Lys Ser Gly Val Met Leu Asp Pro Leu Gln Gln Gln Gln Pro Pro Gln 
    530                 535                 540


Pro Pro Pro Pro Pro Pro Pro Pro Pro Pro Ser Gln Pro Gln Pro Leu 
545                 550                 555                 560


Gln Gln Pro Gln Pro Pro Gln Leu Gln Pro Pro His Gln Val Pro Pro 
                565                 570                 575


Gln Pro Gln Thr Gln Pro Pro Pro Thr Gln Gln Pro Gln Pro Pro Thr 
            580                 585                 590


Gln Ala Ala Pro Leu His Pro Tyr Lys Cys Thr Met Cys Asn Tyr Ser 
        595                 600                 605


Thr Thr Thr Leu Lys Gly Leu Arg Val His Gln Gln His Lys His Ser 
    610                 615                 620


Phe Cys Asp Asn Leu Pro Lys Phe Glu Gly Gln Pro Ser Ser Leu Pro 
625                 630                 635                 640


Leu Glu Asn Glu Thr Asp Ser His Pro Ser Ser Ser Asn Thr Val Lys 
                645                 650                 655


Lys Ser Gln Thr Ser Ile Leu Gly Leu Ser Ser Lys Asn Asn Phe Val 
            660                 665                 670


Ala Lys Ala Ser Arg Lys Leu Ala Asn Asp Phe Pro Leu Asp Leu Ser 
        675                 680                 685


Pro Val Lys Lys Arg Thr Arg Ile Asp Glu Ile Ala Ser Asn Leu Gln 
    690                 695                 700


Ser Lys Ile Asn Gln Thr Lys Gln Gln Glu Asp Ala Val Ile Asn Val 
705                 710                 715                 720


Glu Asp Asp Glu Glu Glu Glu Glu Asp Asn Glu Val Glu Ile Glu Val 
                725                 730                 735


Glu Leu Asp Arg Glu Glu Glu Pro Thr Glu Pro Ile Ile Glu Val Pro 
            740                 745                 750


Thr Ser Phe Ser Ala Gln Gln Ile Trp Val Arg Asp Thr Ser Glu Pro 
        755                 760                 765


Gln Lys Glu Pro Asn Phe Arg Asn Ile Thr His Asp Tyr Asn Ala Thr 
    770                 775                 780


Asn Gly Ala Glu Ile Glu Leu Thr Leu Ser Glu Asp Glu Glu Asp Tyr 
785                 790                 795                 800


Tyr Gly Ser Ser Thr Asn Leu Lys Asp His Gln Val Ser Asn Thr Ala 
                805                 810                 815


Leu Leu Asn Thr Gln Thr Pro Ile Tyr Gly Thr Glu His Asn Ser Glu 
            820                 825                 830


Asn Thr Asp Phe Gly Asp Ser Gly Arg Leu Tyr Tyr Cys Lys His Cys 
        835                 840                 845


Asp Phe Asn Asn Lys Ser Ala Arg Ser Val Ser Thr His Tyr Gln Arg 
    850                 855                 860


Met His Pro Tyr Ile Lys Phe Ser Phe Arg Tyr Ile Leu Asp Pro Asn 
865                 870                 875                 880


Asp His Ser Ala Val Tyr Arg Cys Leu Glu Cys Tyr Ile Asp Tyr Thr 
                885                 890                 895


Asn Phe Glu Asp Leu Gln Gln His Tyr Gly Glu His His Pro Glu Ala 
            900                 905                 910


Met Asn Val Leu Asn Phe Asp His Ser Asp Leu Ile Tyr Arg Cys Arg 
        915                 920                 925


Phe Cys Ser Tyr Thr Ser Pro Asn Val Arg Ser Leu Met Pro His Tyr 
    930                 935                 940


Gln Arg Met His Pro Thr Val Lys Ile Asn Asn Ala Met Ile Phe Ser 
945                 950                 955                 960


Ser Tyr Val Val Glu Gln Gln Glu Gly Leu Asn Thr Glu Ser Gln Thr 
                965                 970                 975


Leu Arg Glu Ile Leu Asn Ser Ala Pro Lys Asn Met Ala Thr Ser Thr 
            980                 985                 990


Pro Val Ala Arg Gly Gly Gly Leu Pro Ala Thr Phe Asn Lys Asn Thr 
        995                 1000                1005


Pro Lys Thr Phe Thr Pro Glu Cys Glu Asn Gln Lys Asp Pro Leu Val 
    1010                1015                1020


Asn Thr Val Val Val Tyr Asp Cys Asp Val Cys Ser Phe Ala Ser Pro 
1025                1030                1035                1040


Asn Met His Ser Val Leu Val His Tyr Gln Lys Lys His Pro Glu Glu 
                1045                1050                1055


Lys Ala Ser Tyr Phe Arg Ile Gln Lys Thr Met Arg Met Val Ser Val 
            1060                1065                1070


Asp Arg Gly Ser Ala Leu Ser Gln Leu Ser Phe Glu Val Gly Ala Pro 
        1075                1080                1085


Met Ser Pro Lys Met Ser Asn Met Gly Ser Pro Pro Pro Pro Gln Pro 
    1090                1095                1100


Pro Pro Pro Asp Leu Ser Thr Glu Leu Tyr Tyr Cys Lys His Cys Ser 
1105                1110                1115                1120


Tyr Ser Asn Arg Ser Val Val Gly Val Leu Val His Tyr Gln Lys Arg 
                1125                1130                1135


His Pro Glu Ile Lys Val Thr Ala Lys Tyr Ile Arg Gln Ala Pro Pro 
            1140                1145                1150


Thr Ala Ala Met Met Arg Gly Val Glu Gly Pro Gln Gly Ser Pro Arg 
        1155                1160                1165


Pro Pro Ala Pro Ile Gln Gln Leu Asn Arg Ser Ser Ser Glu Arg Asp 
    1170                1175                1180


Gly Pro Pro Val Glu Asn Glu Met Phe Phe Cys Gln His Cys Asp Tyr 
1185                1190                1195                1200


Gly Asn Arg Thr Val Lys Gly Val Leu Ile His Tyr Gln Lys Lys His 
                1205                1210                1215


Arg Asp Phe Lys Ala Asn Ala Asp Val Ile Arg Gln His Thr Ala Thr 
            1220                1225                1230


Ile Arg Ser Leu Cys Asp Arg Asn Gln Lys Lys Pro Ala Ser Cys Val 
        1235                1240                1245


Leu Val Ser Pro Ser Asn Leu Glu Arg Asp Lys Thr Lys Leu Arg Ala 
    1250                1255                1260


Leu Lys Cys Arg Gln Cys Ser Tyr Thr Ser Pro Tyr Phe Tyr Ala Leu 
1265                1270                1275                1280


Arg Lys His Ile Lys Lys Asp His Pro Ala Leu Lys Ala Thr Val Thr 
                1285                1290                1295


Ser Ile Met Arg Trp Ala Phe Leu Asp Gly Leu Ile Glu Ala Gly Tyr 
            1300                1305                1310


His Cys Glu Trp Cys Ile Tyr Ser His Thr Glu Pro Asn Gly Leu Leu 
        1315                1320                1325


Leu His Tyr Gln Arg Arg His Pro Glu His Tyr Val Asp Tyr Thr Tyr 
    1330                1335                1340


Met Ala Thr Lys Leu Trp Ala Gly Pro Asp Pro Ser Pro Pro Ser Leu 
1345                1350                1355                1360


Thr Met Pro Ala Glu Ala Lys Thr Tyr Arg Cys Arg Asp Cys Val Phe 
                1365                1370                1375


Glu Ala Val Ser Ile Trp Asp Ile Thr Asn His Tyr Gln Ala Phe His 
            1380                1385                1390


Pro Trp Ala Met Asn Gly Asp Glu Ser Val Leu Leu Asp Ile Ile Lys 
        1395                1400                1405


Glu Lys Asp Ala Val Glu Lys Pro Ile Leu Ser Ser Glu Glu Leu Ala 
    1410                1415                1420


Gly Pro Val Asn Cys Glu Asn Ser Ile Pro Thr Pro Phe Pro Glu Gln 
1425                1430                1435                1440


Glu Ala Glu Cys Pro Glu Asp Ala Arg Leu Ser Pro Glu Lys Ser Leu 
                1445                1450                1455


Gln Leu Ala Ser Ala Asn Pro Ala Ile Ser Ser Thr Pro Tyr Gln Cys 
            1460                1465                1470


Thr Val Cys Gln Ser Glu Tyr Asn Asn Leu His Gly Leu Leu Thr His 
        1475                1480                1485


Tyr Gly Lys Lys His Pro Gly Met Lys Val Lys Ala Ala Asp Phe Ala 
    1490                1495                1500


Gln Asp Ile Asp Ile Asn Pro Gly Ala Val Tyr Lys Cys Arg His Cys 
1505                1510                1515                1520


Pro Tyr Ile Asn Thr Arg Ile His Gly Val Leu Thr His Tyr Gln Lys 
                1525                1530                1535


Arg His Pro Ser Ile Lys Val Thr Ala Glu Asp Phe Val His Asp Val 
            1540                1545                1550


Glu Gln Ser Ala Asp Ile Ser Gln Asn Asp Val Glu Glu Thr Ser Arg 
        1555                1560                1565


Ile Phe Lys Gln Gly Tyr Gly Ala Tyr Arg Cys Lys Leu Cys Pro Tyr 
    1570                1575                1580


Thr His Gly Thr Leu Glu Lys Leu Lys Ile His Tyr Glu Lys Tyr His 
1585                1590                1595                1600


Asn Gln Pro Glu Phe Asp Val Phe Ser Gln Ser Pro Pro Lys Leu Pro 
                1605                1610                1615


Val Pro Leu Glu Pro Glu Met Thr Thr Glu Val Ser Pro Ser Gln Val 
            1620                1625                1630


Ser Ile Thr Glu Glu Glu Val Gly Glu Glu Pro Val Ser Thr Ser His 
        1635                1640                1645


Phe Ser Thr Ser His Leu Val Ser His Thr Val Phe Arg Cys Gln Leu 
    1650                1655                1660


Cys Lys Tyr Phe Cys Ser Thr Arg Lys Gly Ile Ala Arg His Tyr Arg 
1665                1670                1675                1680


Ile Lys His Asn Asn Val Arg Ala Gln Pro Glu Gly Lys Asn Asn Leu 
                1685                1690                1695


Phe Lys Cys Ala Leu Cys Ala Tyr Thr Asn Pro Ile Arg Lys Gly Leu 
            1700                1705                1710


Ala Ala His Tyr Gln Lys Arg His Asp Ile Asp Ala Tyr Tyr Thr His 
        1715                1720                1725


Cys Leu Ala Ala Ser Arg Thr Ile Ser Asp Lys Pro Asn Lys Val Ile 
    1730                1735                1740


Ile Pro Ser Pro Pro Lys Asp Asp Ser Pro Gln Leu Ser Glu Glu Leu 
1745                1750                1755                1760


Arg Arg Ala Val Glu Lys Lys Lys Cys Ser Leu Cys Ser Phe Gln Ser 
                1765                1770                1775


Phe Ser Lys Lys Gly Ile Val Ser His Tyr Met Lys Arg His Pro Gly 
            1780                1785                1790


Val Phe Pro Lys Lys Gln His Ala Ser Lys Leu Gly Gly Tyr Phe Thr 
        1795                1800                1805


Ala Val Tyr Ala Asp Glu His Glu Lys Pro Thr Leu Met Glu Glu Glu 
    1810                1815                1820


Glu Arg Gly Asn Phe Glu Lys Ala Glu Val Glu Gly Glu Ala Gln Glu 
1825                1830                1835                1840


Ile Glu Trp Leu Pro Phe Arg Cys Ile Lys Cys Phe Lys Leu Ser Phe 
                1845                1850                1855


Ser Thr Ala Glu Leu Leu Cys Met His Tyr Thr Asp His His Ser Arg 
            1860                1865                1870


Asp Leu Lys Arg Asp Phe Ile Ile Leu Gly Asn Gly Pro Arg Leu Gln 
        1875                1880                1885


Asn Ser Thr Tyr Gln Cys Lys His Cys Asp Ser Lys Leu Gln Ser Thr 
    1890                1895                1900


Ala Glu Leu Thr Ser His Leu Asn Ile His Asn Glu Glu Phe Gln Lys 
1905                1910                1915                1920


Arg Ala Lys Arg Gln Glu Arg Arg Lys Gln Leu Leu Ser Lys Gln Lys 
                1925                1930                1935


Tyr Ala Asp Gly Ala Phe Ala Asp Phe Lys Gln Glu Arg Pro Phe Gly 
            1940                1945                1950


His Leu Glu Glu Val Pro Lys Ile Lys Glu Arg Lys Val Val Gly Tyr 
        1955                1960                1965


Lys Cys Lys Phe Cys Val Glu Val His Pro Thr Leu Arg Ala Ile Cys 
    1970                1975                1980


Asn His Leu Arg Lys His Val Gln Tyr Gly Asn Val Pro Ala Val Ser 
1985                1990                1995                2000


Ala Ala Val Lys Gly Leu Arg Ser His Glu Arg Ser His Leu Ala Leu 
                2005                2010                2015


Ala Met Phe Thr Arg Glu Asp Lys Tyr Ser Cys Gln Tyr Cys Ser Phe 
            2020                2025                2030


Val Ser Ala Phe Arg His Asn Leu Asp Arg His Met Gln Thr His His 
        2035                2040                2045


Gly His His Lys Pro Phe Arg Cys Lys Leu Cys Ser Phe Lys Ser Ser 
    2050                2055                2060


Tyr Asn Ser Arg Leu Lys Thr His Ile Leu Lys Ala His Ala Gly Glu 
2065                2070                2075                2080


His Ala Tyr Lys Cys Ser Trp Cys Ser Phe Ser Thr Met Thr Ile Ser 
                2085                2090                2095


Gln Leu Lys Glu His Ser Leu Lys Val His Gly Lys Ala Leu Thr Leu 
            2100                2105                2110


Pro Arg Pro Arg Ile Val Ser Leu Leu Ser Ser His Ser His His Ser 
        2115                2120                2125


Ser Gln Lys Ala Thr Pro Ala Glu Glu Val Glu Asp Ser Asn Asp Ser 
    2130                2135                2140


Ser Tyr Ser Glu Pro Pro Asp Val Gln Gln Gln Leu Asn His Tyr Gln 
2145                2150                2155                2160


Ser Ala Ala Leu Ala Arg Asn Asn Ser Arg Val Ser Pro Val Pro Leu 
                2165                2170                2175


Ser Gly Ala Ala Ala Gly Thr Glu Gln Lys Thr Glu Ala Val Leu His 
            2180                2185                2190


Cys Glu Phe Cys Glu Phe Ser Ser Gly Tyr Ile Gln Ser Ile Arg Arg 
        2195                2200                2205


His Tyr Arg Asp Lys His Gly Gly Lys Lys Leu Phe Lys Cys Lys Asp 
    2210                2215                2220


Cys Ser Phe Tyr Thr Gly Phe Lys Ser Ala Phe Thr Met His Val Glu 
2225                2230                2235                2240


Ala Gly His Ser Ala Val Pro Glu Glu Gly Pro Lys Asp Leu Arg Cys 
                2245                2250                2255


Pro Leu Cys Leu Tyr His Thr Lys Tyr Lys Arg Asn Met Ile Asp His 
            2260                2265                2270


Ile Val Leu His Arg Glu Glu Arg Val Val Pro Ile Glu Val Cys Arg 
        2275                2280                2285


Ser Lys Leu Ser Lys Tyr Leu Gln Gly Val Val Phe Arg Cys Asp Lys 
    2290                2295                2300


Cys Thr Phe Thr Cys Ser Ser Asp Glu Ser Leu Gln Gln His Ile Glu 
2305                2310                2315                2320


Lys His Asn Glu Leu Lys Pro Tyr Lys Cys Gln Leu Cys Tyr Tyr Glu 
                2325                2330                2335


Thr Lys His Thr Glu Glu Leu Asp Ser His Leu Arg Asp Glu His Lys 
            2340                2345                2350


Val Ser Arg Asn Phe Glu Leu Val Gly Arg Val Asn Leu Asp Gln Leu 
        2355                2360                2365


Glu Gln Met Lys Glu Lys Met Glu Ser Ser Ser Ser Asp Asp Glu Asp 
    2370                2375                2380


Lys Glu Glu Glu Met Asn Ser Lys Ala Glu Asp Arg Glu Leu Met Arg 
2385                2390                2395                2400


Phe Ser Asp His Gly Ala Ala Leu Asn Thr Glu Lys Arg Phe Pro Cys 
                2405                2410                2415


Glu Phe Cys Gly Arg Ala Phe Ser Gln Gly Ser Glu Trp Glu Arg His 
            2420                2425                2430


Val Leu Arg His Gly Met Ala Leu Asn Asp Thr Lys Gln Val Ser Arg 
        2435                2440                2445


Glu Glu Ile His Pro Lys Glu Ile Met Glu Asn Ser Val Lys Met Pro 
    2450                2455                2460


Ser Ile Glu Glu Lys Glu Asp Asp Glu Ala Ile Gly Ile Asp Phe Ser 
2465                2470                2475                2480


Leu Lys Asn Glu Thr Val Ala Ile Cys Val Val Thr Ala Asp Lys Ser 
                2485                2490                2495


Leu Leu Glu Asn Ala Glu Ala Lys Lys Glu 
            2500                2505


<210>  6188
<211>  5226
<212>  DNA
<213>  Homo sapiens

<400>  6188
tactactgca aacactgttc ctacagcaat cggtcagttg tgggagtgct tgtccactac     60

cagaaaagac acccagaaat aaaggttact gccaaatata tcagacaggc tcctcccaca    120

gctgcaatga tgagaggggt cgaagggccc caaggctccc cccggccacc cgcccccata    180

caacagctga accgaagcag ctctgagaga gatggccctc ctgtggagaa tgagatgttc    240

ttttgccagc actgtgatta tgggaaccgg acggtcaaag gggtactcat tcattatcag    300

aagaagcacc gagacttcaa ggccaatgca gatgtgatcc ggcagcatac ggccaccatt    360

cgaagcctct gcgaccgaaa tcagaagaag cctgccagct gcgtgcttgt ctccccctct    420

aatctggagc gggacaaaac gaaactccga gcactcaaat gtaggcagtg ctcatatacc    480

tccccctact tctatgcact gaggaagcat atcaagaaag accaccccgc cctgaaagcc    540

acagtcacgt ccatcatgcg atgggcattt ctagatggct tgatagaagc tggctaccac    600

tgcgagtggt gcatctactc ccatacggag cccaacggtt tgctcctgca ttaccaacgg    660

aggcatccag aacactatgt tgattacacc tacatggcta ctaaactgtg ggctgggcca    720

gacccatccc ctccctctct cacaatgcca gccgaagcca aaacctacag atgcagggac    780

tgtgttttcg aagctgtttc catctgggac atcactaatc actaccaagc attccacccc    840

tgggccatga atggtgatga gtcagtgcta ctggacatca tcaaggagaa agatgctgtg    900

gagaagccca ttctttcatc cgaagagttg gcaggccctg tgaattgtga aaacagtata    960

cccacccctt tcccggagca ggaagctgaa tgtccagagg atgcaagact gtcccctgag   1020

aaaagcctgc agctagcttc agccaacccc gccatatcct ccaccccata ccagtgcacg   1080

gtatgccaat ctgagtataa caacttgcac ggccttctca ctcattatgg gaagaagcac   1140

cctggcatga aagtgaaggc tgctgacttt gcccaggaca ttgacatcaa cccaggtgcc   1200

gtctacaaat gcaggcattg cccatacatc aacacccgca tccacggcgt actgacccac   1260

taccagaagc gacacccgtc catcaaggtg accgctgagg actttgtgca cgacgtagag   1320

cagtctgctg acatatccca gaatgacgtg gaggagacga gcaggatctt caagcaaggg   1380

tatggcgcct accggtgcaa actgtgtccg tacacacacg gcactttgga gaaactaaaa   1440

atccactacg agaagtatca caatcagcct gaatttgatg tcttttccca gtcgcccccg   1500

aagctgccag tccccctcga gcccgagatg accactgaag tgagcccttc ccaagtctcc   1560

atcactgagg aggaggtggg agaggagccc gtgtccactt ctcacttctc tacctcccac   1620

ctggtctccc acactgtgtt ccggtgccag ctctgcaagt acttctgctc cacgaggaag   1680

gggatcgcca ggcactaccg catcaagcac aataatgtcc gagcccagcc agaaggcaag   1740

aacaacctct tcaagtgtgc cctgtgtgcc tacaccaacc ccatccgcaa aggtctggca   1800

gcccactacc agaagcgcca cgacattgat gcgtattaca ctcactgctt ggcagcctcc   1860

aggaccatca gcgacaagcc caacaaagtg atcatcccat ccccgcccaa ggacgactcc   1920

cctcagctga gcgaggaact ccggcgggca gtggagaaga aaaagtgctc cttgtgctct   1980

ttccagtcgt tcagcaagaa gggcatcgtg tcccattaca tgaaacgcca cccaggggtg   2040

ttcccaaaga agcagcacgc cagcaagttg gggggctact tcacggccgt ctatgcagat   2100

gagcatgaga agcccacact gatggaagaa gaggagagag gcaactttga gaaagccgag   2160

gtggagggtg aagctcagga aatcgagtgg ctcccattcc gctgcatcaa atgcttcaag   2220

ctgtccttta gcactgcaga gctgctgtgc atgcattaca ctgaccacca cagtcgggac   2280

ctaaagaggg acttcatcat tctgggcaac ggcccccgct tgcagaactc cacctaccag   2340

tgtaagcact gtgatagcaa actgcaaagc acagccgagc tgacctcaca cttgaacatt   2400

cacaatgagg aattccagaa gcgtgccaaa cgtcaggaga ggaggaaaca gcttttgagc   2460

aagcagaaat atgcagatgg tgcttttgca gatttcaaac aagagaggcc ttttggtcac   2520

ttagaagagg tgccaaagat caaggagagg aaagtggtgg gctacaaatg taaattctgt   2580

gtggaagtgc acccaacgct ccgagccatc tgcaatcacc tccgaaagca cgtccagtat   2640

ggcaatgtcc cagctgtgtc agctgctgtg aaggaggcgg atgaccctgc ccacttgttc   2700

ctggatggat tggaagcagc caaagacgcc agtggcgccc tggtgggccg ggtggatggt   2760

gaacactgct tgcttgatgg aatgttggag gatgaaaccc ggccgggggg ataccattgc   2820

agtcaatgtg acagagtcct gatgtccatg caggggctgc gttctcatga gaggagccac   2880

ctggccctgg ccatgtttac ccgcgaggac aagtacagct gccagtattg ctcgtttgtt   2940

tctgctttca ggcacaattt ggatcgccat atgcaaaccc accacggaca ccataaacca   3000

ttccgatgca aactctgctc cttcaagtcc tcctataaca gccggctgaa aacacatata   3060

ctcaaagctc atgctggtga gcatgcctac aagtgttctt ggtgctcatt ctccaccatg   3120

acaatcagcc agctgaagga acactccctc aaggtccacg gaaaagccct gaccctcccc   3180

aggccacgga tcgtcagtct cctctcctca cactcccacc actcctccca aaaagctacc   3240

ccggctgaag aagtggaaga ctccaatgac tcatcatatt cagagccccc agatgttcag   3300

cagcagttga accactatca gtcagctgcc ctggcaagga acaacagccg tgttagccct   3360

gtgcctcttt ctggggctgc tgctggcact gagcagaaaa ctgaagccgt gcttcactgc   3420

gaattctgtg aattctcctc cggctacatc cagagcatca ggcgtcatta ccgggacaag   3480

catggtggga agaagctttt caagtgcaaa gactgctcct tttacacagg ctttaaatct   3540

gcttttacta tgcacgtgga agctgggcac tcagcagttc ccgaggaggg ccccaaagat   3600

cttcgctgtc ctctctgcct ctatcacacc aaatacaagc gcaacatgat tgaccacatc   3660

gtgctgcacc gagaagagcg tgttgtcccc attgaagttt gccggtccaa actgtccaaa   3720

tacttgcagg gagtagtttt ccgctgtgat aagtgtacct tcacctgctc cagtgatgag   3780

agcctccagc aacatataga aaagcacaat gaactgaaac cttacaaatg ccagctctgc   3840

tactatgaga ccaagcacac ggaggaactg gacagccacc ttcgggatga gcataaggta   3900

agccgtaact ttgagctggt tggacgggtt aacttggatc agctggaaca gatgaaggag   3960

aaaatggaga gctccagcag cgatgatgag gacaaggaag aagaaatgaa cagcaaggct   4020

gaagacagag agctgatgag attttctgac cacggggctg ctcttaacac tgagaagcgt   4080

tttccatgtg aattttgtgg acgggcgttt tcacagggct ctgagtggga aagacatgtg   4140

ctgagacacg gcatggcatt gaatgacacc aagcaggtga gcagagaaga aatccaccca   4200

aaagagatca tggagaacag tgttaaaatg ccctccatag aggaaaagga agatgacgag   4260

gccattggga tagacttttc cctaaagaat gaaacagtag ccatctgtgt agtaactgcc   4320

gacaaatctc tcctggagaa tgcagaggcc aaaaaagaat gagcgtttgg tgaaattctt   4380

aatcaaacct tacttgaaca gtgatgaaaa agtgggaggg ctggcttggg ctgagaaggg   4440

agggacagaa aagagaagac agaacaaagc tgctttttag gactgaacaa tctattttca   4500

aagcactggt acctgtgtga gtgagtatgt aaattaaagt tatttaaatg gttggaatat   4560

gtggctcctt ttccatcact acatcttttc ttccggatct tcatcatgga agtttcattt   4620

gttgcggaat atggaagcac ctcccaatgg tacggtgcac cctgtggtgg tcttggacag   4680

tatgtggaaa cagaagctcc atgacggtag aagacttctc attggggagc aactttttga   4740

cgcacaactt ttggtgcgtt tttctagttt taatacctta agctttttca agacctaact   4800

gcagccgctt tgggaaaaaa aaacaaaaaa caaaaaacag aaaacaaaaa aaaaaaaact   4860

gctttgcata aaacagtcac ctgtttccta gtacctcaaa cttaaccaag ggaactctct   4920

gcatttgtca gtactacctg tcgtcgttgt ggttaaatgt agagagaact gctgggcaag   4980

atggtgaatg gagaaaaaaa aagagtttta aagaaaggaa cacaaattgt gcttaaaatc   5040

cccatgtggg ttttatttct taaaatactg tgattttttt aattatttta gtaaaaaaca   5100

aaacaaaaaa aagaaacaga ctttaattat tagataactg tttgtgaatt gtcatccttt   5160

attccaggta agctgtttat tagtgttcaa ctataattta gaatttggta gattcatgtg   5220

agctaa                                                              5226


<210>  6189
<211>  1411
<212>  PRT
<213>  Homo sapiens

<400>  6189

Met Met Arg Gly Val Glu Gly Pro Gln Gly Ser Pro Arg Pro Pro Ala 
1               5                   10                  15


Pro Ile Gln Gln Leu Asn Arg Ser Ser Ser Glu Arg Asp Gly Pro Pro 
            20                  25                  30


Val Glu Asn Glu Met Phe Phe Cys Gln His Cys Asp Tyr Gly Asn Arg 
        35                  40                  45


Thr Val Lys Gly Val Leu Ile His Tyr Gln Lys Lys His Arg Asp Phe 
    50                  55                  60


Lys Ala Asn Ala Asp Val Ile Arg Gln His Thr Ala Thr Ile Arg Ser 
65                  70                  75                  80


Leu Cys Asp Arg Asn Gln Lys Lys Pro Ala Ser Cys Val Leu Val Ser 
                85                  90                  95


Pro Ser Asn Leu Glu Arg Asp Lys Thr Lys Leu Arg Ala Leu Lys Cys 
            100                 105                 110


Arg Gln Cys Ser Tyr Thr Ser Pro Tyr Phe Tyr Ala Leu Arg Lys His 
        115                 120                 125


Ile Lys Lys Asp His Pro Ala Leu Lys Ala Thr Val Thr Ser Ile Met 
    130                 135                 140


Arg Trp Ala Phe Leu Asp Gly Leu Ile Glu Ala Gly Tyr His Cys Glu 
145                 150                 155                 160


Trp Cys Ile Tyr Ser His Thr Glu Pro Asn Gly Leu Leu Leu His Tyr 
                165                 170                 175


Gln Arg Arg His Pro Glu His Tyr Val Asp Tyr Thr Tyr Met Ala Thr 
            180                 185                 190


Lys Leu Trp Ala Gly Pro Asp Pro Ser Pro Pro Ser Leu Thr Met Pro 
        195                 200                 205


Ala Glu Ala Lys Thr Tyr Arg Cys Arg Asp Cys Val Phe Glu Ala Val 
    210                 215                 220


Ser Ile Trp Asp Ile Thr Asn His Tyr Gln Ala Phe His Pro Trp Ala 
225                 230                 235                 240


Met Asn Gly Asp Glu Ser Val Leu Leu Asp Ile Ile Lys Glu Lys Asp 
                245                 250                 255


Ala Val Glu Lys Pro Ile Leu Ser Ser Glu Glu Leu Ala Gly Pro Val 
            260                 265                 270


Asn Cys Glu Asn Ser Ile Pro Thr Pro Phe Pro Glu Gln Glu Ala Glu 
        275                 280                 285


Cys Pro Glu Asp Ala Arg Leu Ser Pro Glu Lys Ser Leu Gln Leu Ala 
    290                 295                 300


Ser Ala Asn Pro Ala Ile Ser Ser Thr Pro Tyr Gln Cys Thr Val Cys 
305                 310                 315                 320


Gln Ser Glu Tyr Asn Asn Leu His Gly Leu Leu Thr His Tyr Gly Lys 
                325                 330                 335


Lys His Pro Gly Met Lys Val Lys Ala Ala Asp Phe Ala Gln Asp Ile 
            340                 345                 350


Asp Ile Asn Pro Gly Ala Val Tyr Lys Cys Arg His Cys Pro Tyr Ile 
        355                 360                 365


Asn Thr Arg Ile His Gly Val Leu Thr His Tyr Gln Lys Arg His Pro 
    370                 375                 380


Ser Ile Lys Val Thr Ala Glu Asp Phe Val His Asp Val Glu Gln Ser 
385                 390                 395                 400


Ala Asp Ile Ser Gln Asn Asp Val Glu Glu Thr Ser Arg Ile Phe Lys 
                405                 410                 415


Gln Gly Tyr Gly Ala Tyr Arg Cys Lys Leu Cys Pro Tyr Thr His Gly 
            420                 425                 430


Thr Leu Glu Lys Leu Lys Ile His Tyr Glu Lys Tyr His Asn Gln Pro 
        435                 440                 445


Glu Phe Asp Val Phe Ser Gln Ser Pro Pro Lys Leu Pro Val Pro Leu 
    450                 455                 460


Glu Pro Glu Met Thr Thr Glu Val Ser Pro Ser Gln Val Ser Ile Thr 
465                 470                 475                 480


Glu Glu Glu Val Gly Glu Glu Pro Val Ser Thr Ser His Phe Ser Thr 
                485                 490                 495


Ser His Leu Val Ser His Thr Val Phe Arg Cys Gln Leu Cys Lys Tyr 
            500                 505                 510


Phe Cys Ser Thr Arg Lys Gly Ile Ala Arg His Tyr Arg Ile Lys His 
        515                 520                 525


Asn Asn Val Arg Ala Gln Pro Glu Gly Lys Asn Asn Leu Phe Lys Cys 
    530                 535                 540


Ala Leu Cys Ala Tyr Thr Asn Pro Ile Arg Lys Gly Leu Ala Ala His 
545                 550                 555                 560


Tyr Gln Lys Arg His Asp Ile Asp Ala Tyr Tyr Thr His Cys Leu Ala 
                565                 570                 575


Ala Ser Arg Thr Ile Ser Asp Lys Pro Asn Lys Val Ile Ile Pro Ser 
            580                 585                 590


Pro Pro Lys Asp Asp Ser Pro Gln Leu Ser Glu Glu Leu Arg Arg Ala 
        595                 600                 605


Val Glu Lys Lys Lys Cys Ser Leu Cys Ser Phe Gln Ser Phe Ser Lys 
    610                 615                 620


Lys Gly Ile Val Ser His Tyr Met Lys Arg His Pro Gly Val Phe Pro 
625                 630                 635                 640


Lys Lys Gln His Ala Ser Lys Leu Gly Gly Tyr Phe Thr Ala Val Tyr 
                645                 650                 655


Ala Asp Glu His Glu Lys Pro Thr Leu Met Glu Glu Glu Glu Arg Gly 
            660                 665                 670


Asn Phe Glu Lys Ala Glu Val Glu Gly Glu Ala Gln Glu Ile Glu Trp 
        675                 680                 685


Leu Pro Phe Arg Cys Ile Lys Cys Phe Lys Leu Ser Phe Ser Thr Ala 
    690                 695                 700


Glu Leu Leu Cys Met His Tyr Thr Asp His His Ser Arg Asp Leu Lys 
705                 710                 715                 720


Arg Asp Phe Ile Ile Leu Gly Asn Gly Pro Arg Leu Gln Asn Ser Thr 
                725                 730                 735


Tyr Gln Cys Lys His Cys Asp Ser Lys Leu Gln Ser Thr Ala Glu Leu 
            740                 745                 750


Thr Ser His Leu Asn Ile His Asn Glu Glu Phe Gln Lys Arg Ala Lys 
        755                 760                 765


Arg Gln Glu Arg Arg Lys Gln Leu Leu Ser Lys Gln Lys Tyr Ala Asp 
    770                 775                 780


Gly Ala Phe Ala Asp Phe Lys Gln Glu Arg Pro Phe Gly His Leu Glu 
785                 790                 795                 800


Glu Val Pro Lys Ile Lys Glu Arg Lys Val Val Gly Tyr Lys Cys Lys 
                805                 810                 815


Phe Cys Val Glu Val His Pro Thr Leu Arg Ala Ile Cys Asn His Leu 
            820                 825                 830


Arg Lys His Val Gln Tyr Gly Asn Val Pro Ala Val Ser Ala Ala Val 
        835                 840                 845


Lys Glu Ala Asp Asp Pro Ala His Leu Phe Leu Asp Gly Leu Glu Ala 
    850                 855                 860


Ala Lys Asp Ala Ser Gly Ala Leu Val Gly Arg Val Asp Gly Glu His 
865                 870                 875                 880


Cys Leu Leu Asp Gly Met Leu Glu Asp Glu Thr Arg Pro Gly Gly Tyr 
                885                 890                 895


His Cys Ser Gln Cys Asp Arg Val Leu Met Ser Met Gln Gly Leu Arg 
            900                 905                 910


Ser His Glu Arg Ser His Leu Ala Leu Ala Met Phe Thr Arg Glu Asp 
        915                 920                 925


Lys Tyr Ser Cys Gln Tyr Cys Ser Phe Val Ser Ala Phe Arg His Asn 
    930                 935                 940


Leu Asp Arg His Met Gln Thr His His Gly His His Lys Pro Phe Arg 
945                 950                 955                 960


Cys Lys Leu Cys Ser Phe Lys Ser Ser Tyr Asn Ser Arg Leu Lys Thr 
                965                 970                 975


His Ile Leu Lys Ala His Ala Gly Glu His Ala Tyr Lys Cys Ser Trp 
            980                 985                 990


Cys Ser Phe Ser Thr Met Thr Ile Ser Gln Leu Lys Glu His Ser Leu 
        995                 1000                1005


Lys Val His Gly Lys Ala Leu Thr Leu Pro Arg Pro Arg Ile Val Ser 
    1010                1015                1020


Leu Leu Ser Ser His Ser His His Ser Ser Gln Lys Ala Thr Pro Ala 
1025                1030                1035                1040


Glu Glu Val Glu Asp Ser Asn Asp Ser Ser Tyr Ser Glu Pro Pro Asp 
                1045                1050                1055


Val Gln Gln Gln Leu Asn His Tyr Gln Ser Ala Ala Leu Ala Arg Asn 
            1060                1065                1070


Asn Ser Arg Val Ser Pro Val Pro Leu Ser Gly Ala Ala Ala Gly Thr 
        1075                1080                1085


Glu Gln Lys Thr Glu Ala Val Leu His Cys Glu Phe Cys Glu Phe Ser 
    1090                1095                1100


Ser Gly Tyr Ile Gln Ser Ile Arg Arg His Tyr Arg Asp Lys His Gly 
1105                1110                1115                1120


Gly Lys Lys Leu Phe Lys Cys Lys Asp Cys Ser Phe Tyr Thr Gly Phe 
                1125                1130                1135


Lys Ser Ala Phe Thr Met His Val Glu Ala Gly His Ser Ala Val Pro 
            1140                1145                1150


Glu Glu Gly Pro Lys Asp Leu Arg Cys Pro Leu Cys Leu Tyr His Thr 
        1155                1160                1165


Lys Tyr Lys Arg Asn Met Ile Asp His Ile Val Leu His Arg Glu Glu 
    1170                1175                1180


Arg Val Val Pro Ile Glu Val Cys Arg Ser Lys Leu Ser Lys Tyr Leu 
1185                1190                1195                1200


Gln Gly Val Val Phe Arg Cys Asp Lys Cys Thr Phe Thr Cys Ser Ser 
                1205                1210                1215


Asp Glu Ser Leu Gln Gln His Ile Glu Lys His Asn Glu Leu Lys Pro 
            1220                1225                1230


Tyr Lys Cys Gln Leu Cys Tyr Tyr Glu Thr Lys His Thr Glu Glu Leu 
        1235                1240                1245


Asp Ser His Leu Arg Asp Glu His Lys Val Ser Arg Asn Phe Glu Leu 
    1250                1255                1260


Val Gly Arg Val Asn Leu Asp Gln Leu Glu Gln Met Lys Glu Lys Met 
1265                1270                1275                1280


Glu Ser Ser Ser Ser Asp Asp Glu Asp Lys Glu Glu Glu Met Asn Ser 
                1285                1290                1295


Lys Ala Glu Asp Arg Glu Leu Met Arg Phe Ser Asp His Gly Ala Ala 
            1300                1305                1310


Leu Asn Thr Glu Lys Arg Phe Pro Cys Glu Phe Cys Gly Arg Ala Phe 
        1315                1320                1325


Ser Gln Gly Ser Glu Trp Glu Arg His Val Leu Arg His Gly Met Ala 
    1330                1335                1340


Leu Asn Asp Thr Lys Gln Val Ser Arg Glu Glu Ile His Pro Lys Glu 
1345                1350                1355                1360


Ile Met Glu Asn Ser Val Lys Met Pro Ser Ile Glu Glu Lys Glu Asp 
                1365                1370                1375


Asp Glu Ala Ile Gly Ile Asp Phe Ser Leu Lys Asn Glu Thr Val Ala 
            1380                1385                1390


Ile Cys Val Val Thr Ala Asp Lys Ser Leu Leu Glu Asn Ala Glu Ala 
        1395                1400                1405


Lys Lys Glu 
    1410


<210>  6190
<211>  1444
<212>  DNA
<213>  Homo sapiens

<400>  6190
tgatgcgtat tacactcact gcttggcagc ctccaggacc atcagcgaca agcccaacaa     60

agtgatcatc ccatccccgc ccaaggacga ctcccctcag ctgagcgagg aactccggcg    120

ggcagtggag aagaaaaagt gctccttgtg ctctttccag tcgttcagca agaagggcat    180

cgtgtcccat tacatgaaac gccacccagg ggtgttccca aagaagcagc acgccagcaa    240

gttggggggc tacttcacgg ccgtctatgc agatgagcat gagaagccca cactgatgga    300

agaagaggag agaggcaact ttgagaaagc cgaggtggag ggtgaagctc aggaaatcga    360

gtggctccca ttccgctgca tcaaatgctt caagctgtcc tttagcactg cagagctgct    420

gtgcatgcat tacactgacc accacagtcg ggacctaaag agggacttca tcattctggg    480

caacggcccc cgcttgcaga actccaccta ccagtgtaag cactgtgata gcaaactgca    540

aagcacagcc gagctgacct cacacttgaa cattcacaat gaggaattcc agaagcgtgc    600

caaacgtcag gagaggagga aacagctttt gagcaagcag aaatatgcag atggtgcttt    660

tgcagatttc aaacaagaga ggccttttgg tcacttagaa gaggtgccaa agatcaagga    720

gaggaaagtg gtgggctaca aatgtaaatt ctgtgtggaa gtgcacccaa cgctccgagc    780

catctgcaat cacctccgaa agcacgtcca gtatggcaat gtcccagctg tgtcagctgc    840

tgtgaaggtt ggaccttcct catctttctg ttcagggaaa ggtcgagttt cgatctggtt    900

tccttccacg cggatagttt ggtggcagca gaaggtccag gattctcggt ctaggaggct    960

tcgggtcgtc cttctattct gcgtttagtg ccattagctc ttcgttcttc caagttgccc   1020

gagctcttga gaggaatcaa gaggcggatg accctgccca cttgttcctg gatggattgg   1080

aagcagccaa agacgccagt ggcgccctgg tgggccgggt ggatggtgaa cactgcttgc   1140

ttgatggaat gttggaggat gaaacccggc cggggggata ccattgcagt caatgtgaca   1200

gagtcctgat gtccatgcag gggctgcgtt ctcatgagag gagccacctg gccctggcca   1260

tgtttacccg cgaggacaag tacagctgcc agtattgctc gtttgtttct gctttcaggc   1320

acaatttgga tcgccatatg caaacccacc acggacacca taaaccattc cgatgcaaac   1380

tctgctcctt caagtcctcc tataacagcc ggctgaaaac acatatactc aaagctcatg   1440

ctgg                                                                1444


<210>  6191
<211>  264
<212>  PRT
<213>  Homo sapiens

<400>  6191

Met Lys Arg His Pro Gly Val Phe Pro Lys Lys Gln His Ala Ser Lys 
1               5                   10                  15


Leu Gly Gly Tyr Phe Thr Ala Val Tyr Ala Asp Glu His Glu Lys Pro 
            20                  25                  30


Thr Leu Met Glu Glu Glu Glu Arg Gly Asn Phe Glu Lys Ala Glu Val 
        35                  40                  45


Glu Gly Glu Ala Gln Glu Ile Glu Trp Leu Pro Phe Arg Cys Ile Lys 
    50                  55                  60


Cys Phe Lys Leu Ser Phe Ser Thr Ala Glu Leu Leu Cys Met His Tyr 
65                  70                  75                  80


Thr Asp His His Ser Arg Asp Leu Lys Arg Asp Phe Ile Ile Leu Gly 
                85                  90                  95


Asn Gly Pro Arg Leu Gln Asn Ser Thr Tyr Gln Cys Lys His Cys Asp 
            100                 105                 110


Ser Lys Leu Gln Ser Thr Ala Glu Leu Thr Ser His Leu Asn Ile His 
        115                 120                 125


Asn Glu Glu Phe Gln Lys Arg Ala Lys Arg Gln Glu Arg Arg Lys Gln 
    130                 135                 140


Leu Leu Ser Lys Gln Lys Tyr Ala Asp Gly Ala Phe Ala Asp Phe Lys 
145                 150                 155                 160


Gln Glu Arg Pro Phe Gly His Leu Glu Glu Val Pro Lys Ile Lys Glu 
                165                 170                 175


Arg Lys Val Val Gly Tyr Lys Cys Lys Phe Cys Val Glu Val His Pro 
            180                 185                 190


Thr Leu Arg Ala Ile Cys Asn His Leu Arg Lys His Val Gln Tyr Gly 
        195                 200                 205


Asn Val Pro Ala Val Ser Ala Ala Val Lys Val Gly Pro Ser Ser Ser 
    210                 215                 220


Phe Cys Ser Gly Lys Gly Arg Val Ser Ile Trp Phe Pro Ser Thr Arg 
225                 230                 235                 240


Ile Val Trp Trp Gln Gln Lys Val Gln Asp Ser Arg Ser Arg Arg Leu 
                245                 250                 255


Arg Val Val Leu Leu Phe Cys Val 
            260


<210>  6192
<211>  2277
<212>  DNA
<213>  Homo sapiens

<400>  6192
acagatggac ctcacagtct cgcaactaac atgggaacca gtaatctcat gccagaggaa     60

gcactcctga ggcagaggag atttcaggag agaacaggtt gaacattaat aaggaggagc    120

tttggcactg gtccaagaaa caggataagc taaatctctg catctattct ggacaccaga    180

atggcgcggg gaccatttag aggtgagatg ggcagatgag gagctgaagt ttcagagagg    240

ttaagcaatt tgcctaggtt cacacagcaa agatgatgaa acttacaacc acaagcaatc    300

cccagaagca gccctttcac agagaggaag ctgaggctta gagggtgtca atggatgatc    360

cagtgctgca gagccagaag ggccaccata acaatgaaat ggaggcagca tacattggta    420

atggaaagag catgggagtt tggaagtcaa aagagatgga tgttttctga ccttgataag    480

gactctgaaa atgatcctta caagtaaaca gaagagacca caaataacca gtgacaggta    540

atgtgatgag acatgggatc aaaggactgc gattgactgc ttaccagttg ggtgactttg    600

agtgagtgat tccagctctc atgtgccctg caaaacttac tattgtattt atgatgggca    660

caatatgcac tacgtcacac actgtgccct tcaggaaaac ctgctagaca aattcctcta    720

ggtttcagtg tctaggattc ctgaaaattt cctgaatgac agttcaaaaa agtctaacaa    780

gcagttgaaa tctggttgct tctgtgggtt tcttttctac catggtaggc aaggaatctc    840

agggcgaaat ctgcagccca ctgtgaacaa gggcatggca cctcatggta tccactgggt    900

atccaaactc tcagctagct ttttcatact tagaggtgaa ctttccacta gtttcttctt    960

attttgcatt taccccaatt tccttatttg tttttaaacc tatagttcgg cacacacgtc   1020

tttaagatat cttaaaacct ttgtgaaatg aagtagatgg caaataagta cattaaatta   1080

ttttaaaaat agtttgtctc actctcaagt ttcacaggca tacaacggga atagagtaat   1140

agtatccttc acaatgttgc tggaagatga agtgactgtg cgtgtaagcg gcactttgtt   1200

gagggtagaa tgctatggga gtatttgtgg tcgtagtgtt taatctctct ttgcttcccc   1260

ctttcttgtg ttctcagctc agggagggaa agtcattgag cttgttaggc atcaaagctc   1320

tgttcctgcc aggcagcaat atgggaaaag aagggaacca accacagaaa gtgaagactc   1380

gccatgtctg ctcggcagca gccctgctga tggcccctta ccaagctgtg atagggcaca   1440

gagccaccgc aacacatggg ctgggggacc ggaagccagg tgactgaggc ggaacaccag   1500

gcgggaccac tcgggccaag aattcctgcc taaatgttcc tatgatactt ctcccagctt   1560

gcaggtggac atcctagcca gcaacgatct catgtctcat tagagtgcaa gggggaggag   1620

ggaaatctgt gcatgttaaa tgtccagcct tccattgagt ttgcatgaac atgggtgagt   1680

atgtcacaaa tgtattggcc aaaggcaatg gctcaggggc aatgtgaggt gtgttgccaa   1740

tggcccccaa atactcagca tttcagagtg agtgacatcc cagcaagaca acagatgaca   1800

ctcattgctt ttgaggcata tgtgacaaat attggaaggc tttctaaggt cagaggcgaa   1860

ggaatgaaga taggagggaa gaggatgaaa agaagggatg gagagaaaga atgaagtaga   1920

tggaaagatc agtagaaaca ccaatcaaga ctggcaatga gtactccagt aatctttttc   1980

tatccacctg tagcttgaat cttttcagga cgaaacagat tctacatatt tttccttcca   2040

atgcagagga aggctgttgt ttaacagtgt tttaattggc caagggtaaa tgcaactcaa   2100

agaaagaccg aagtggactt aaaagaagta tcactgttta tcagcaggaa ccaacattta   2160

ttgagcagtc attatgcatc cattatgaaa aaccactgga cactttaccc attatctcat   2220

aggtacaatc atctctttta atggatggag aggttaaaca cagtgggctc taaaacc      2277


<210>  6193
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  6193

Met Ile Gln Cys Cys Arg Ala Arg Arg Ala Thr Ile Thr Met Lys Trp 
1               5                   10                  15


Arg Gln His Thr Leu Val Met Glu Arg Ala Trp Glu Phe Gly Ser Gln 
            20                  25                  30


Lys Arg Trp Met Phe Ser Asp Leu Asp Lys Asp Ser Glu Asn Asp Pro 
        35                  40                  45


Tyr Lys 
    50


<210>  6194
<211>  1552
<212>  DNA
<213>  Homo sapiens

<400>  6194
ctgatataaa tcatcacaca agggagagaa taaatcggaa aaaataatgc tcagattcct     60

ttggaatctc gggcaagcgg ctcttcagtc aagaaagacc cagattttgt gatagaagca    120

ttggggaggt gaggcgaaat gaggtcttgg ggcccaagaa ccagaaacag ttctcgaatg    180

ctattcaagg aatgccctaa gggggaaacc taagaaaaag tgaggaatct ggaaattgct    240

ttcaccacat ggctttatca gtgaaggtag gagagagggt atcctaatga atgctgactt    300

acctattctg ctgattccca cagcacacag gtaacacttc tgctttctct ttgcagagct    360

gatgagattt tctgaccacg gggctgctct taacactgag aagcgttttc catgtgaatt    420

ttgtggacgg gcgttttcac agggctctga gtgggaaaga catgtgctga gacacggcat    480

ggcattgaat gacaccaagc aggtgagcag agaagaaatc cacccaaaag agatcatgga    540

gaacagtgtt aaaatgccct ccatagagga aaaggaagat gacgaggcca ttgggataga    600

cttttcccta aagaatgaaa cagtagccat ctgtgtagta actgccgaca aatctctcct    660

ggagaatgca gaggccaaaa aagaatgagc gtttggtgaa attcttaatc aaaccttact    720

tgaacagtga tgaaaaagtg ggagggctgg cttgggctga gaagggaggg acagaaaaga    780

gaagacagaa caaagctgct ttttaggact gaacaatcta ttttcaaagc actggtacct    840

gtgtgagtga gtatgtaaat taaagttatt taaatggttg gaatatgtgg ctccttttcc    900

atcactacat cttttcttcc ggatcttcat catggaagtt tcatttgttg cggaatatgg    960

aagcacctcc caatggtacg gtgcaccctg tggtggtctt ggacagtatg tggaaacaga   1020

agctccatga cggtagaaga cttctcattg gggagcaact ttttgacgca caacttttgg   1080

tgcgtttttc tagttttaat accttaagct ttttcaagac ctaactgcag ccgctttggg   1140

aaaaaaaaac aaaaaacaaa aaacagaaaa caaaaaaaaa aaaactgctt tgcataaaac   1200

agtcacctgt ttcctagtac ctcaaactta accaagggaa ctctctgcat ttgtcagtac   1260

tacctgtcgt cgttgtggtt aaatgtagag agaactgctg ggcaagatgg tgaatggaga   1320

aaaaaaaaga gttttaaaga aaggaacaca aattgtgctt aaaatcccca tgtgggtttt   1380

atttcttaaa atactgtgat ttttttaatt attttagtaa aaaacaaaac aaaaaaaaga   1440

aacagacttt aattattaga taactgtttg tgaattgtca tcctttattc caggtaagct   1500

gtttattagt gttcaactat aatttagaat ttggtagatt catgtgagct aa           1552


<210>  6195
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  6195

Met Arg Phe Ser Asp His Gly Ala Ala Leu Asn Thr Glu Lys Arg Phe 
1               5                   10                  15


Pro Cys Glu Phe Cys Gly Arg Ala Phe Ser Gln Gly Ser Glu Trp Glu 
            20                  25                  30


Arg His Val Leu Arg His Gly Met Ala Leu Asn Asp Thr Lys Gln Val 
        35                  40                  45


Ser Arg Glu Glu Ile His Pro Lys Glu Ile Met Glu Asn Ser Val Lys 
    50                  55                  60


Met Pro Ser Ile Glu Glu Lys Glu Asp Asp Glu Ala Ile Gly Ile Asp 
65                  70                  75                  80


Phe Ser Leu Lys Asn Glu Thr Val Ala Ile Cys Val Val Thr Ala Asp 
                85                  90                  95


Lys Ser Leu Leu Glu Asn Ala Glu Ala Lys Lys Glu 
            100                 105


<210>  6196
<211>  2485
<212>  DNA
<213>  Homo sapiens

<400>  6196
acgcggtctg tgggagaccg gagcgggaga cagcggtgac aggagcagcg gccgggagcc     60

cttagggagg cagacagagc ctgcagccaa tgccccagga gccctcggtt ccaaccaact    120

gatgcccctg tgcccactgg cccacgccat gcagccccag tccgttctgc acagcggcta    180

cttccaccca ctacttcggg cctggctctc cgagctgtgg accgggatgt acgggaagga    240

gctgacatgc tcatggtgaa gccgggaatg ccctacctgg acatcgtgcg ggaggtaaag    300

gacaagcacc ctgacctccc tctcgccgtg taccacgtct ctggagagtt tgccatgctg    360

tggcatggag cccaggccgg ggcatttgat ctcaaggctg ccgtactgga ggccatgact    420

gccttccgca gagcaggtgc tgacatcatc atcacctact acacaccgca gctgctgcag    480

tggctgaagg aggaatgatg gagacagtgc caggcccaag aactagaact ttaaaacgtt    540

cccggggcct cagacaagtg aaaaccaaag taaatgctgc ttttagaact gtgccctcat    600

gccctcttcc tgctcacatg ctagcggggc ccagcagccc tgggtggttt tgccagcatg    660

ctaactcttg taactcgcag ctgcatccta tgagctctcc caagcttccc cgcccctccc    720

ctgggtcagc cgtgaggccc acctttgcca ccctcagctc tttcctctgg tgtggcttca    780

gcttgaaagc aacctggagt cgggggcaca gcctttgggg cctggctggg agagggtctt    840

ggagcattag gggaagaaga gagcagtggg atcttggggc ctgagaagcc ttggaacgct    900

tctggcagca gagctgggtg tgggaatgag gcctagatcg atatccctgg gttagagttg    960

aaatttgccg caattccact ggaaggcatt tcccacgagg ccagaggttg ccaggctgcc   1020

tgaggtctcc tattctactc tgaaccataa acccagagaa gaattactca ttaaccagca   1080

taaatactgc ctgaggatca aaactcagag gcaaagaggg agttcctgac tgctagaggt   1140

gccaccacca caaacacttt ttattcagga gatacttttt gagaatctct gctctgttcc   1200

taggttcagt gctgggtcct gggaatacag caggacagac ctcagcttat ctcttcatag   1260

aaattataca aagagaattg gggagacagc taagaagaaa acaaagaaat aaagcagtta   1320

caaattgtga taagtgcttt gaaggaaaga aggggtctga gacaacaaca gggaaggggc   1380

ctctcttgaa acagtagttg ggaaggaggc agacatgcac cagtgatgtg gtgacaggtg   1440

ctctgaagga ggtcaccagg acctgacctc tttgaaggat cagaaaatac ttccctgaag   1500

gactgacatt tgagcctaga cctgaagggt gagccatcaa gctaagacaa ttggggaaga   1560

gcattccagg gagagggagg agttgtgcaa aggccctggg gctccttcta gctggaggaa   1620

tgcaaggcta gcttgtctgg agcactgaga ggatggcctg aactgagtgg agagagacag   1680

accaggacca aaccatgcag aggtcaaggg ccacattcac cttttcagag tgactcaatc   1740

aaatttgtag tttgtaaaag tattttaaca gctctgcggc aaagtgcaaa tgaaaagtct   1800

tgatggcatg gactggagcg gggacagtgg ggatggagaa aggggaatgg attgtggatg   1860

tgtttagaag gtagattcga tgtgaaggat gaatctggct tgaccttctg ggtggctgat   1920

gggccattta ctgagatggg gcagcctgga agaggaacag aagcagggtc ggggtggagg   1980

gagaatacta aacttagctt gagacatttt gcaataagga agctatatct agagtgctta   2040

tgtgactcac ctaaggccac tcaacaagtt tgtggcagaa ctggattaga actgcacaga   2100

aaacagccaa gctgggattt gaacccatgt agtccaactc caaggcctct gcccctaacc   2160

actgtgccat accacctccc aataatcaac agcaaaatta taggtctaac aatgttttat   2220

agacacccct ccatttatgt gatgggtttg catcctgata aacccatcat aagttgaaaa   2280

tatgatcata agttgaaaat atgatcataa gtcaaaaatg tatttaatat acctaaccta   2340

ccaaacatca tagcttagcc tagcctgcct taaacatgct cagaacactt acattagcct   2400

acagtgggca aaactatcca acacaaaatc tatattgtaa taaagttgta aagaattttg   2460

aataaaaatt caatatttga agtac                                         2485


<210>  6197
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  6197

Met Leu Met Val Lys Pro Gly Met Pro Tyr Leu Asp Ile Val Arg Glu 
1               5                   10                  15


Val Lys Asp Lys His Pro Asp Leu Pro Leu Ala Val Tyr His Val Ser 
            20                  25                  30


Gly Glu Phe Ala Met Leu Trp His Gly Ala Gln Ala Gly Ala Phe Asp 
        35                  40                  45


Leu Lys Ala Ala Val Leu Glu Ala Met Thr Ala Phe Arg Arg Ala Gly 
    50                  55                  60


Ala Asp Ile Ile Ile Thr Tyr Tyr Thr Pro Gln Leu Leu Gln Trp Leu 
65                  70                  75                  80


Lys Glu Glu 



<210>  6198
<211>  2379
<212>  DNA
<213>  Homo sapiens

<400>  6198
tacgcggtct gtgggagacc ggagcgggag acagcggtga caggagcact tttggggacc     60

gccgctgcta ccagctgccc cctggagcac gaggcctggc tctccgagct gtggaccggg    120

atgtacggga aggagctgac atgctcatgg tgaagccggg aatgccctac ctggacatcg    180

tgcgggaggt aaaggacaag caccctgacc tccctctcgc cgtgtaccac gtctctggag    240

agtttgccat gctgtggcat ggagcccagg ccggggcatt tgatctcaag gctgccgtac    300

tggaggccat gactgccttc cgcagagcag gtgctgacat catcatcacc tactacacac    360

cgcagctgct gcagtggctg aaggaggaat gatggagaca gtgccaggcc caagaactag    420

aactttaaaa cgttcccggg gcctcagaca agtgaaaacc aaagtaaatg ctgcttttag    480

aactgtgccc tcatgccctc ttcctgctca catgctagcg gggcccagca gccctgggtg    540

gttttgccag catgctaact cttgtaactc gcagctgcat cctatgagct ctcccaagct    600

tccccgcccc tcccctgggt cagccgtgag gcccaccttt gccaccctca gctctttcct    660

ctggtgtggc ttcagcttga aagcaacctg gagtcggggg cacagccttt ggggcctggc    720

tgggagaggg tcttggagca ttaggggaag aagagagcag tgggatcttg gggcctgaga    780

agccttggaa cgcttctggc agcagagctg ggtgtgggaa tgaggcctag atcgatatcc    840

ctgggttaga gttgaaattt gccgcaattc cactggaagg catttcccac gaggccagag    900

gttgccaggc tgcctgaggt ctcctattct actctgaacc ataaacccag agaagaatta    960

ctcattaacc agcataaata ctgcctgagg atcaaaactc agaggcaaag agggagttcc   1020

tgactgctag aggtgccacc accacaaaca ctttttattc aggagatact ttttgagaat   1080

ctctgctctg ttcctaggtt cagtgctggg tcctgggaat acagcaggac agacctcagc   1140

ttatctcttc atagaaatta tacaaagaga attggggaga cagctaagaa gaaaacaaag   1200

aaataaagca gttacaaatt gtgataagtg ctttgaagga aagaaggggt ctgagacaac   1260

aacagggaag gggcctctct tgaaacagta gttgggaagg aggcagacat gcaccagtga   1320

tgtggtgaca ggtgctctga aggaggtcac caggacctga cctctttgaa ggatcagaaa   1380

atacttccct gaaggactga catttgagcc tagacctgaa gggtgagcca tcaagctaag   1440

acaattgggg aagagcattc cagggagagg gaggagttgt gcaaaggccc tggggctcct   1500

tctagctgga ggaatgcaag gctagcttgt ctggagcact gagaggatgg cctgaactga   1560

gtggagagag acagaccagg accaaaccat gcagaggtca agggccacat tcaccttttc   1620

agagtgactc aatcaaattt gtagtttgta aaagtatttt aacagctctg cggcaaagtg   1680

caaatgaaaa gtcttgatgg catggactgg agcggggaca gtggggatgg agaaagggga   1740

atggattgtg gatgtgttta gaaggtagat tcgatgtgaa ggatgaatct ggcttgacct   1800

tctgggtggc tgatgggcca tttactgaga tggggcagcc tggaagagga acagaagcag   1860

ggtcggggtg gagggagaat actaaactta gcttgagaca ttttgcaata aggaagctat   1920

atctagagtg cttatgtgac tcacctaagg ccactcaaca agtttgtggc agaactggat   1980

tagaactgca cagaaaacag ccaagctggg atttgaaccc atgtagtcca actccaaggc   2040

ctctgcccct aaccactgtg ccataccacc tcccaataat caacagcaaa attataggtc   2100

taacaatgtt ttatagacac ccctccattt atgtgatggg tttgcatcct gataaaccca   2160

tcataagttg aaaatatgat cataagttga aaatatgatc ataagtcaaa aatgtattta   2220

atatacctaa cctaccaaac atcatagctt agcctagcct gccttaaaca tgctcagaac   2280

acttacatta gcctacagtg ggcaaaacta tccaacacaa aatctatatt gtaataaagt   2340

tgtaaagaat tttgaataaa aattcaatat ttgaagtac                          2379


<210>  6199
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  6199

Met Leu Met Val Lys Pro Gly Met Pro Tyr Leu Asp Ile Val Arg Glu 
1               5                   10                  15


Val Lys Asp Lys His Pro Asp Leu Pro Leu Ala Val Tyr His Val Ser 
            20                  25                  30


Gly Glu Phe Ala Met Leu Trp His Gly Ala Gln Ala Gly Ala Phe Asp 
        35                  40                  45


Leu Lys Ala Ala Val Leu Glu Ala Met Thr Ala Phe Arg Arg Ala Gly 
    50                  55                  60


Ala Asp Ile Ile Ile Thr Tyr Tyr Thr Pro Gln Leu Leu Gln Trp Leu 
65                  70                  75                  80


Lys Glu Glu 



<210>  6200
<211>  3348
<212>  DNA
<213>  Homo sapiens

<400>  6200
gtggaggggg cggaccgtgg ggaagctgct tccgggtgag ccccccccgc tcttacgcgg     60

tctgtgggag accggagcgg gagacagcgg tgacaggagc agcggccggg agcccttagg    120

gaggcagaca gagcctgcag ccaatgcccc aggagccctc ggttccaacc aactgatgcc    180

cctgtgccca ctggcccacg ccatgcagcc ccagtccgtt ctgcacagcg gctacttcca    240

cccactactt cgggcctggc agacagccac caccaccctc aatgcctcca acctcatcta    300

ccccatcttt gtcacgccct gggcttggcc aggcagggaa gccagacact ggatcccatc    360

ctcctcccac catctccact tccatatttc tttcctgctt cccaaccatc cctctcagtc    420

gcccccgcac cactggccct tcccacagct accaatccat atcccacccc cgctcttgca    480

gggatgttcc tgatgacata cagcctatca ccagcctccc aggagtggcc aggtatggtg    540

tgaagcggct ggaagagatg ctgaggccct tggtggaaga gggcctacgc tgtgtcttga    600

tctttggcgt ccccagcaga gttcccaagg acgagcgggg ttccgcagct gactccgagg    660

agtccccagc tattgaggca atccatctgt tgaggaagac cttccccaac ctcctggtgg    720

cctgtgatgt ctgcctgtgt ccctacacct cccatggtca ctgcgggctc ctgagtgaaa    780

acggagcatt ccgggctgag gagagccgcc agcggctggc tgaggtggca ttggcgtatg    840

ccaaggcagg atgtcaggtg gtagccccgt cggacatgat ggatggacgc gtggaagcca    900

tcaaagaggc cctgatggca catggacttg gcaacagggt atcggtgatg agctacagtg    960

ccaaatttgc ttcctgtttc tatggccctt tccgggatgc agctaagtca agcccagctt   1020

ttggggaccg ccgctgctac cagctgcccc ctggagcacg aggcctggct ctccgagctg   1080

tggaccggga tgtacgggaa ggagctgaca tgctcatggt gaagccggga atgccctacc   1140

tggacatcgt gcgggaggta aaggacaagc accctgacct ccctctcgcc gtgtaccacg   1200

tctctggaga gtttgccatg ctgtggcatg gagcccaggc cggggcattt gatctcaagg   1260

ctgccgtact ggaggccatg actgccttcc gcagagcagg tgctgacatc atcatcacct   1320

actacacacc gcagctgctg cagtggctga aggaggaatg atggagacag tgccaggccc   1380

aagaactaga actttaaaac gttcccgggg cctcagacaa gtgaaaacca aagtaaatgc   1440

tgcttttaga actgtgccct catgccctct tcctgctcac atgctagcgg ggcccagcag   1500

ccctgggtgg ttttgccagc atgctaactc ttgtaactcg cagctgcatc ctatgagctc   1560

tcccaagctt ccccgcccct cccctgggtc agccgtgagg cccacctttg ccaccctcag   1620

ctctttcctc tggtgtggct tcagcttgaa agcaacctgg agtcgggggc acagcctttg   1680

gggcctggct gggagagggt cttggagcat taggggaaga agagagcagt gggatcttgg   1740

ggcctgagaa gccttggaac gcttctggca gcagagctgg gtgtgggaat gaggcctaga   1800

tcgatatccc tgggttagag ttgaaatttg ccgcaattcc actggaaggc atttcccacg   1860

aggccagagg ttgccaggct gcctgaggtc tcctattcta ctctgaacca taaacccaga   1920

gaagaattac tcattaacca gcataaatac tgcctgagga tcaaaactca gaggcaaaga   1980

gggagttcct gactgctaga ggtgccacca ccacaaacac tttttattca ggagatactt   2040

tttgagaatc tctgctctgt tcctaggttc agtgctgggt cctgggaata cagcaggaca   2100

gacctcagct tatctcttca tagaaattat acaaagagaa ttggggagac agctaagaag   2160

aaaacaaaga aataaagcag ttacaaattg tgataagtgc tttgaaggaa agaaggggtc   2220

tgagacaaca acagggaagg ggcctctctt gaaacagtag ttgggaagga ggcagacatg   2280

caccagtgat gtggtgacag gtgctctgaa ggaggtcacc aggacctgac ctctttgaag   2340

gatcagaaaa tacttccctg aaggactgac atttgagcct agacctgaag ggtgagccat   2400

caagctaaga caattgggga agagcattcc agggagaggg aggagttgtg caaaggccct   2460

ggggctcctt ctagctggag gaatgcaagg ctagcttgtc tggagcactg agaggatggc   2520

ctgaactgag tggagagaga cagaccagga ccaaaccatg cagaggtcaa gggccacatt   2580

caccttttca gagtgactca atcaaatttg tagtttgtaa aagtatttta acagctctgc   2640

ggcaaagtgc aaatgaaaag tcttgatggc atggactgga gcggggacag tggggatgga   2700

gaaaggggaa tggattgtgg atgtgtttag aaggtagatt cgatgtgaag gatgaatctg   2760

gcttgacctt ctgggtggct gatgggccat ttactgagat ggggcagcct ggaagaggaa   2820

cagaagcagg gtcggggtgg agggagaata ctaaacttag cttgagacat tttgcaataa   2880

ggaagctata tctagagtgc ttatgtgact cacctaaggc cactcaacaa gtttgtggca   2940

gaactggatt agaactgcac agaaaacagc caagctggga tttgaaccca tgtagtccaa   3000

ctccaaggcc tctgccccta accactgtgc cataccacct cccaataatc aacagcaaaa   3060

ttataggtct aacaatgttt tatagacacc cctccattta tgtgatgggt ttgcatcctg   3120

ataaacccat cataagttga aaatatgatc ataagttgaa aatatgatca taagtcaaaa   3180

atgtatttaa tatacctaac ctaccaaaca tcatagctta gcctagcctg ccttaaacat   3240

gctcagaaca cttacattag cctacagtgg gcaaaactat ccaacacaaa atctatattg   3300

taataaagtt gtaaagaatt ttgaataaaa attcaatatt tgaagtac                3348


<210>  6201
<211>  359
<212>  PRT
<213>  Homo sapiens

<400>  6201

Met Pro Pro Thr Ser Ser Thr Pro Ser Leu Ser Arg Pro Gly Leu Gly 
1               5                   10                  15


Gln Ala Gly Lys Pro Asp Thr Gly Ser His Pro Pro Pro Thr Ile Ser 
            20                  25                  30


Thr Ser Ile Phe Leu Ser Cys Phe Pro Thr Ile Pro Leu Ser Arg Pro 
        35                  40                  45


Arg Thr Thr Gly Pro Ser His Ser Tyr Gln Ser Ile Ser His Pro Arg 
    50                  55                  60


Ser Cys Arg Asp Val Pro Asp Asp Ile Gln Pro Ile Thr Ser Leu Pro 
65                  70                  75                  80


Gly Val Ala Arg Tyr Gly Val Lys Arg Leu Glu Glu Met Leu Arg Pro 
                85                  90                  95


Leu Val Glu Glu Gly Leu Arg Cys Val Leu Ile Phe Gly Val Pro Ser 
            100                 105                 110


Arg Val Pro Lys Asp Glu Arg Gly Ser Ala Ala Asp Ser Glu Glu Ser 
        115                 120                 125


Pro Ala Ile Glu Ala Ile His Leu Leu Arg Lys Thr Phe Pro Asn Leu 
    130                 135                 140


Leu Val Ala Cys Asp Val Cys Leu Cys Pro Tyr Thr Ser His Gly His 
145                 150                 155                 160


Cys Gly Leu Leu Ser Glu Asn Gly Ala Phe Arg Ala Glu Glu Ser Arg 
                165                 170                 175


Gln Arg Leu Ala Glu Val Ala Leu Ala Tyr Ala Lys Ala Gly Cys Gln 
            180                 185                 190


Val Val Ala Pro Ser Asp Met Met Asp Gly Arg Val Glu Ala Ile Lys 
        195                 200                 205


Glu Ala Leu Met Ala His Gly Leu Gly Asn Arg Val Ser Val Met Ser 
    210                 215                 220


Tyr Ser Ala Lys Phe Ala Ser Cys Phe Tyr Gly Pro Phe Arg Asp Ala 
225                 230                 235                 240


Ala Lys Ser Ser Pro Ala Phe Gly Asp Arg Arg Cys Tyr Gln Leu Pro 
                245                 250                 255


Pro Gly Ala Arg Gly Leu Ala Leu Arg Ala Val Asp Arg Asp Val Arg 
            260                 265                 270


Glu Gly Ala Asp Met Leu Met Val Lys Pro Gly Met Pro Tyr Leu Asp 
        275                 280                 285


Ile Val Arg Glu Val Lys Asp Lys His Pro Asp Leu Pro Leu Ala Val 
    290                 295                 300


Tyr His Val Ser Gly Glu Phe Ala Met Leu Trp His Gly Ala Gln Ala 
305                 310                 315                 320


Gly Ala Phe Asp Leu Lys Ala Ala Val Leu Glu Ala Met Thr Ala Phe 
                325                 330                 335


Arg Arg Ala Gly Ala Asp Ile Ile Ile Thr Tyr Tyr Thr Pro Gln Leu 
            340                 345                 350


Leu Gln Trp Leu Lys Glu Glu 
        355


<210>  6202
<211>  3185
<212>  DNA
<213>  Homo sapiens

<400>  6202
actgtggagg gggcggaccg tggggaagct gcttccgggt gagccccccc cgctcttacg     60

cggtctgtgg gagaccggag cgggagacag cggtgacagg agcagcggcc gggagccctt    120

agggaggcag acagagcctg cagccaatgc cccaggagcc ctcggttcca accaactgat    180

gcccctgtgc ccactggccc acgccatgca gccccagtcc gttctgcaca gcggctactt    240

ccacccacta cttcgggcct ggcagacagc caccaccacc ctcaatgcct ccaacctcat    300

ctaccccatc tttgtcacgg atgttcctga tgacatacag cctatcacca gcctcccagg    360

agtggccagg tatggtgtga agcggctgga agagatgctg aggcccttgg tggaagaggg    420

cctacgctgt gtcttgatct ttggcgtccc cagcagagtt cccaaggacg agcggggttc    480

cgcagctgac tccgaggagt ccccagctat tgaggcaatc catctgttga ggaagacctt    540

ccccaacctc ctggtggcct gtgatgtctg cctgtgtccc tacacctccc atggtcactg    600

cgggctcctg agtgaaaacg gagcattccg ggctgaggag agccgccagc ggctggctga    660

ggtggcattg gcgtatgcca aggcaggatg tcaggtggta gccccgtcgg acatgatgga    720

tggacgcgtg gaagccatca aagaggccct gatggcacat ggacttggca acagggtatc    780

ggtgatgagc tacagtgcca aatttgcttc ctgtttctat ggccctttcc gggatgcagc    840

taagtcaagc ccagcttttg gggaccgccg ctgctaccag ctgccccctg gagcacgagg    900

cctggctctc cgagctgtgg accgggatgt acgggaagga gctgacatgc tcatggtgaa    960

gccgggaatg ccctacctgg acatcgtgcg ggaggtaaag gacaagcacc ctgacctccc   1020

tctcgccgtg taccacgtct ctggagagtt tgccatgctg tggcatggag cccaggccgg   1080

ggcatttgat ctcaaggctg ccgtactgga ggccatgact gccttccgca gagcaggtgc   1140

tgacatcatc atcacctact acacaccgca gctgctgcag tggctgaagg aggaatgatg   1200

gagacagtgc caggcccaag aactagaact ttaaaacgtt cccggggcct cagacaagtg   1260

aaaaccaaag taaatgctgc ttttagaact gtgccctcat gccctcttcc tgctcacatg   1320

ctagcggggc ccagcagccc tgggtggttt tgccagcatg ctaactcttg taactcgcag   1380

ctgcatccta tgagctctcc caagcttccc cgcccctccc ctgggtcagc cgtgaggccc   1440

acctttgcca ccctcagctc tttcctctgg tgtggcttca gcttgaaagc aacctggagt   1500

cgggggcaca gcctttgggg cctggctggg agagggtctt ggagcattag gggaagaaga   1560

gagcagtggg atcttggggc ctgagaagcc ttggaacgct tctggcagca gagctgggtg   1620

tgggaatgag gcctagatcg atatccctgg gttagagttg aaatttgccg caattccact   1680

ggaaggcatt tcccacgagg ccagaggttg ccaggctgcc tgaggtctcc tattctactc   1740

tgaaccataa acccagagaa gaattactca ttaaccagca taaatactgc ctgaggatca   1800

aaactcagag gcaaagaggg agttcctgac tgctagaggt gccaccacca caaacacttt   1860

ttattcagga gatacttttt gagaatctct gctctgttcc taggttcagt gctgggtcct   1920

gggaatacag caggacagac ctcagcttat ctcttcatag aaattataca aagagaattg   1980

gggagacagc taagaagaaa acaaagaaat aaagcagtta caaattgtga taagtgcttt   2040

gaaggaaaga aggggtctga gacaacaaca gggaaggggc ctctcttgaa acagtagttg   2100

ggaaggaggc agacatgcac cagtgatgtg gtgacaggtg ctctgaagga ggtcaccagg   2160

acctgacctc tttgaaggat cagaaaatac ttccctgaag gactgacatt tgagcctaga   2220

cctgaagggt gagccatcaa gctaagacaa ttggggaaga gcattccagg gagagggagg   2280

agttgtgcaa aggccctggg gctccttcta gctggaggaa tgcaaggcta gcttgtctgg   2340

agcactgaga ggatggcctg aactgagtgg agagagacag accaggacca aaccatgcag   2400

aggtcaaggg ccacattcac cttttcagag tgactcaatc aaatttgtag tttgtaaaag   2460

tattttaaca gctctgcggc aaagtgcaaa tgaaaagtct tgatggcatg gactggagcg   2520

gggacagtgg ggatggagaa aggggaatgg attgtggatg tgtttagaag gtagattcga   2580

tgtgaaggat gaatctggct tgaccttctg ggtggctgat gggccattta ctgagatggg   2640

gcagcctgga agaggaacag aagcagggtc ggggtggagg gagaatacta aacttagctt   2700

gagacatttt gcaataagga agctatatct agagtgctta tgtgactcac ctaaggccac   2760

tcaacaagtt tgtggcagaa ctggattaga actgcacaga aaacagccaa gctgggattt   2820

gaacccatgt agtccaactc caaggcctct gcccctaacc actgtgccat accacctccc   2880

aataatcaac agcaaaatta taggtctaac aatgttttat agacacccct ccatttatgt   2940

gatgggtttg catcctgata aacccatcat aagttgaaaa tatgatcata agttgaaaat   3000

atgatcataa gtcaaaaatg tatttaatat acctaaccta ccaaacatca tagcttagcc   3060

tagcctgcct taaacatgct cagaacactt acattagcct acagtgggca aaactatcca   3120

acacaaaatc tatattgtaa taaagttgta aagaattttg aataaaaatt caatatttga   3180

agtac                                                               3185


<210>  6203
<211>  339
<212>  PRT
<213>  Homo sapiens

<400>  6203

Met Pro Leu Cys Pro Leu Ala His Ala Met Gln Pro Gln Ser Val Leu 
1               5                   10                  15


His Ser Gly Tyr Phe His Pro Leu Leu Arg Ala Trp Gln Thr Ala Thr 
            20                  25                  30


Thr Thr Leu Asn Ala Ser Asn Leu Ile Tyr Pro Ile Phe Val Thr Asp 
        35                  40                  45


Val Pro Asp Asp Ile Gln Pro Ile Thr Ser Leu Pro Gly Val Ala Arg 
    50                  55                  60


Tyr Gly Val Lys Arg Leu Glu Glu Met Leu Arg Pro Leu Val Glu Glu 
65                  70                  75                  80


Gly Leu Arg Cys Val Leu Ile Phe Gly Val Pro Ser Arg Val Pro Lys 
                85                  90                  95


Asp Glu Arg Gly Ser Ala Ala Asp Ser Glu Glu Ser Pro Ala Ile Glu 
            100                 105                 110


Ala Ile His Leu Leu Arg Lys Thr Phe Pro Asn Leu Leu Val Ala Cys 
        115                 120                 125


Asp Val Cys Leu Cys Pro Tyr Thr Ser His Gly His Cys Gly Leu Leu 
    130                 135                 140


Ser Glu Asn Gly Ala Phe Arg Ala Glu Glu Ser Arg Gln Arg Leu Ala 
145                 150                 155                 160


Glu Val Ala Leu Ala Tyr Ala Lys Ala Gly Cys Gln Val Val Ala Pro 
                165                 170                 175


Ser Asp Met Met Asp Gly Arg Val Glu Ala Ile Lys Glu Ala Leu Met 
            180                 185                 190


Ala His Gly Leu Gly Asn Arg Val Ser Val Met Ser Tyr Ser Ala Lys 
        195                 200                 205


Phe Ala Ser Cys Phe Tyr Gly Pro Phe Arg Asp Ala Ala Lys Ser Ser 
    210                 215                 220


Pro Ala Phe Gly Asp Arg Arg Cys Tyr Gln Leu Pro Pro Gly Ala Arg 
225                 230                 235                 240


Gly Leu Ala Leu Arg Ala Val Asp Arg Asp Val Arg Glu Gly Ala Asp 
                245                 250                 255


Met Leu Met Val Lys Pro Gly Met Pro Tyr Leu Asp Ile Val Arg Glu 
            260                 265                 270


Val Lys Asp Lys His Pro Asp Leu Pro Leu Ala Val Tyr His Val Ser 
        275                 280                 285


Gly Glu Phe Ala Met Leu Trp His Gly Ala Gln Ala Gly Ala Phe Asp 
    290                 295                 300


Leu Lys Ala Ala Val Leu Glu Ala Met Thr Ala Phe Arg Arg Ala Gly 
305                 310                 315                 320


Ala Asp Ile Ile Ile Thr Tyr Tyr Thr Pro Gln Leu Leu Gln Trp Leu 
                325                 330                 335


Lys Glu Glu 



<210>  6204
<211>  593
<212>  DNA
<213>  Homo sapiens

<400>  6204
acgcggtctg tgggagaccg gagcgggaga cagcggtgac aggagcagcg gccgggagcc     60

cttagggagg cagacagagc ctgcagccaa tgccccagga gccctcggtt ccaaccaact    120

gatgcccctg tgcccactgg cccacgccat gcagccccag tccgttctgc acagcggcta    180

cttccaccca ctacttcggg cctggctctc cgagctgtgg accgggatgt acgggaagga    240

gctgacatgc tcatggtgaa gccgggaatg ccctacctgg acatcgtgcg ggaggtaaag    300

gacaagcacc ctgacctccc tctcgccgtg taccacgtct ctggagagtt tgccatgctg    360

tggcatggag cccaggccgg ggcatttgat ctcaaggctg ccgtactgga ggccatgact    420

gccttccgca gagcaggtgc tgacatcatc atcacctact acacaccgca gctgctgcag    480

tggctgaagg aggaatgatg gagacagtgc caggcccaag aactagaact ttaaaacgtt    540

cccggggcct cagacaagtg aaaaccaaag taaatgctgc ttttagaact gtg           593


<210>  6205
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  6205

Met Leu Met Val Lys Pro Gly Met Pro Tyr Leu Asp Ile Val Arg Glu 
1               5                   10                  15


Val Lys Asp Lys His Pro Asp Leu Pro Leu Ala Val Tyr His Val Ser 
            20                  25                  30


Gly Glu Phe Ala Met Leu Trp His Gly Ala Gln Ala Gly Ala Phe Asp 
        35                  40                  45


Leu Lys Ala Ala Val Leu Glu Ala Met Thr Ala Phe Arg Arg Ala Gly 
    50                  55                  60


Ala Asp Ile Ile Ile Thr Tyr Tyr Thr Pro Gln Leu Leu Gln Trp Leu 
65                  70                  75                  80


Lys Glu Glu 



<210>  6206
<211>  567
<212>  DNA
<213>  Homo sapiens

<400>  6206
acgcggtctg tgggagaccg gagcgggaga cagcggtgac aggagcagcg gccgggagcc     60

cttagggagg cagacagagc ctgcagccaa tgccccagga gccctcggtt ccaaccaact    120

gatgcccctg tgcccactgg cccacgccat gcagccccag tccgttctgc acagcggcta    180

cttccaccca ctacttcggg cctggcagac agccaccacc accctcaatg cctccaacct    240

catctacccc atctttgtca cgacgagcgg ggttccgcag ctgactccga ggagtcccca    300

gctattgagg caatccatct gttgaggaag accttcccca acctcctggt ggcctgtgat    360

gtctgcctgt gtccctacac ctcccatggt cactgcggtg agttccctcc ctcccaccag    420

ccctgctgcc acccacactc ctactgccca cttctcaaca gggtggggac aggccagggc    480

ccaaggtgct ccccaaaacc cagtcatctg tcctgaaggg ctcctgagtg aaaacggagc    540

attccgggct gaggagagcc gccagcg                                        567


<210>  6207
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  6207

Met Pro Leu Cys Pro Leu Ala His Ala Met Gln Pro Gln Ser Val Leu 
1               5                   10                  15


His Ser Gly Tyr Phe His Pro Leu Leu Arg Ala Trp Gln Thr Ala Thr 
            20                  25                  30


Thr Thr Leu Asn Ala Ser Asn Leu Ile Tyr Pro Ile Phe Val Thr Thr 
        35                  40                  45


Ser Gly Val Pro Gln Leu Thr Pro Arg Ser Pro Gln Leu Leu Arg Gln 
    50                  55                  60


Ser Ile Cys 
65


<210>  6208
<211>  604
<212>  DNA
<213>  Homo sapiens

<400>  6208
cttacgcggt ctgtgggaga ccggagcggg agacagcggt gacaggagca gcggccggga     60

gcccttaggg aggcagacag agcctgcagc caatgcccca ggagccctcg gttccaacca    120

actgatgccc ctgtgcccac tggcccacgc catgcagccc cagtccgttc tgcacagcgg    180

ctacttccac ccactacttc gggcctggca gacagccacc accaccctca atgcctccaa    240

cctcatctac cccatctttg tcacggatgt tcctgatgac atacagccta tcaccagcct    300

cccaggagtg gccaggtatg gtgtgaagcg gctggaagag atgctgaggc ccttggtgga    360

agagggccta cgctgtgtct tgatctttgg cgtccccagc agagttccca aggacgagcg    420

gggttccgca gctgactccg aggagtcccc agctattgag gcaatccatc tgttgaggaa    480

gaccttcccc aacctcctgg tggcctgtga tgtctgcctg tgtccctaca cctcccatgg    540

tcactgcggt gagttccctc cctcccacca gccctgctgc cacccacact cctactgccc    600

actt                                                                 604


<210>  6209
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  6209

Met Pro Leu Cys Pro Leu Ala His Ala Met Gln Pro Gln Ser Val Leu 
1               5                   10                  15


His Ser Gly Tyr Phe His Pro Leu Leu Arg Ala Trp Gln Thr Ala Thr 
            20                  25                  30


Thr Thr Leu Asn Ala Ser Asn Leu Ile Tyr Pro Ile Phe Val Thr Asp 
        35                  40                  45


Val Pro Asp Asp Ile Gln Pro Ile Thr Ser Leu Pro Gly Val Ala Arg 
    50                  55                  60


Tyr Gly Val Lys Arg Leu Glu Glu Met Leu Arg Pro Leu Val Glu Glu 
65                  70                  75                  80


Gly Leu Arg Cys Val Leu Ile Phe Gly Val Pro Ser Arg Val Pro Lys 
                85                  90                  95


Asp Glu Arg Gly Ser Ala Ala Asp Ser Glu Glu Ser Pro Ala Ile Glu 
            100                 105                 110


Ala Ile His Leu Leu Arg Lys Thr Phe Pro Asn Leu Leu Val Ala Cys 
        115                 120                 125


Asp Val Cys Leu Cys Pro Tyr Thr Ser His Gly His Cys Gly Glu Phe 
    130                 135                 140


Pro Pro Ser His Gln Pro Cys Cys His Pro His Ser Tyr Cys Pro 
145                 150                 155


<210>  6210
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  6210
acgcggtctg tgggagaccg gagcgggaga cagcggtgac aggagcagcg gccgggagcc     60

cttagggagg cagacagagc ctgcagccaa tgccccagga gccctcggtt ccaaccaact    120

gatgcccctg tgcccactgg cccacgccat gcagccccag tccgttctgc acagcggcta    180

cttccaccca ctacttcggg cctggcagac agccaccacc accctcaatg cctccaacct    240

catctacccc atctttgtca cgtgagtctc caagaatggg ccaggcctct gctctgctgg    300

ttggggttgg ggttggggag ggagtgttga ctggagcggg catcagtatg gctgggggtg    360

gcaaagtgag ctgtcagctt gaaattcaag gcactggaag caggctactt ggattaagga    420

caggaatctt aggaacaaaa caaactttga aagaactcat tcatcccatt tggaaaatta    480

gaagaataac ccttgcctgc catcctgagc tcttgcagta agacagaagc tgagaaggtg    540

ctctgta                                                              547


<210>  6211
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  6211

Met Pro Pro Thr Ser Ser Thr Pro Ser Leu Ser Arg Glu Ser Pro Arg 
1               5                   10                  15


Met Gly Gln Ala Ser Ala Leu Leu Val Gly Val Gly Val Gly Glu Gly 
            20                  25                  30


Val Leu Thr Gly Ala Gly Ile Ser Met Ala Gly Gly Gly Lys Val Ser 
        35                  40                  45


Cys Gln Leu Glu Ile Gln Gly Thr Gly Ser Arg Leu Leu Gly Leu Arg 
    50                  55                  60


Thr Gly Ile Leu Gly Thr Lys Gln Thr Leu Lys Glu Leu Ile His Pro 
65                  70                  75                  80


Ile Trp Lys Ile Arg Arg Ile Thr Leu Ala Cys His Pro Glu Leu Leu 
                85                  90                  95


Gln 



<210>  6212
<211>  944
<212>  DNA
<213>  Homo sapiens

<400>  6212
aaggatctcc cagttcacct gggagttaac acaccagggt tctagtcctt ttgctcgctg     60

tgtggctttg ggtaagtcct tgcccctctc tggaccttga ggtcccattc atacaaaaag    120

cagttggact caggcctgcc agcccccatt tttgtggctc ttccccgccc ctccccatcc    180

tttggctatg ggatagtctc ccaggcacct ccaaaaggaa gtgtctaaaa cagagctctc    240

cacctcctct ccaagcccag ctccccactg ccctcttcct gccctgtccc tgtctccgct    300

gccctttaga tcaggcaggc aggcaggcct agagcatccg ccctgagaca ctgcctgttg    360

gctgccttaa gacgcccctt ccttctctgc ccgcagcctc cccagcctct gcattcctct    420

gcttcctgtc tgctctgctc agcctgcagg attgatcttc ccaaagccag gtgtcaacca    480

ggccactaac cctacccact gctcagaaat cttcccacag cctcagcctg gccccctctt    540

atccatcccc tccatacaca cttgcctcag ctcctcaaaa cagtccacag ccatcctcct    600

tccccacctt tgcccctttc ttcccttcct aaggaaatat tggccccctt ctctccacca    660

ggctgaaccc actcatcctg caaaaccaag ttcaacgccc tgtcattttc tttttttttt    720

ttttttttga gatggagtct cacactgtcg cccaggctag agtgcaatgg gtgcactctc    780

ggctcactgc aacctctgcc tcctaggttc aatcgattct tctgcctcag cctccagagg    840

aactctgact acagacagag cctgcagcca atgccccagg agccctcggt tccaaccaac    900

tgatgcccct gtgcccactg gcccacgcca tgcagcccca gtcc                     944


<210>  6213
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  6213

Met Gly Ala Leu Ser Ala His Cys Asn Leu Cys Leu Leu Gly Ser Ile 
1               5                   10                  15


Asp Ser Ser Ala Ser Ala Ser Arg Gly Thr Leu Thr Thr Asp Arg Ala 
            20                  25                  30


Cys Ser Gln Cys Pro Arg Ser Pro Arg Phe Gln Pro Thr Asp Ala Pro 
        35                  40                  45


Val Pro Thr Gly Pro Arg His Ala Ala Pro 
    50                  55


<210>  6214
<211>  1435
<212>  DNA
<213>  Homo sapiens

<400>  6214
aaaaaaacag actcggaaga gcaagacaag agcagggatg aggacaatga tgaagacgaa     60

gaaaggctgg aagaagaaga acagaatgaa gaggaagaag tagacaactg aaaagggcgg    120

gagactgtgg caccttggaa ggtaccactt gaaatgagac gtgctacgtg tttctgtgaa    180

gcttttccat gctgggcaga gtagtctcag gcaaaagtgc ctgaaaagat cagaataaaa    240

actgactaga aataccgtca aaaccagcac ttaccaaact cagagcatct gagtagcaga    300

atcctgtttt gcttcatcaa tctgaaggtt atggcctttt gacaagaggg attctgaacg    360

actaaattag tcagtttgct cgcttttgtt tacttaaatg tatggttaga tggtttttga    420

tctgcagtct tccctagtcc cccaaataag taataataac ttccatgctg cctgctgtgt    480

tccagatcac agaggcagcc aaggctcagg aaaaactggg gctttgctta tggtcagcct    540

atgtttgatt gcacagtctt tgacaatagt agcttactaa gactgctcag aatgagtaag    600

ctttaggaaa ctactaaaat gctgtgggag aataacaaaa tccgttctct ctcttcactt    660

gacagaagca ttaactgaat tttgtttttc atagacccac ttggcccaaa acctttctat    720

attgcctgta gatgatcggc ctgctggtgt ggtagtaatc tgatcacaga tattcttaaa    780

tcagcagtgt ggaatggtat tagtcaaaca tggtgccagt gtcttttaca aaaacagatg    840

gcatagtgtc agatgtacct tactctctgc tactgtacag ctttaggatt tgtcatcacc    900

tcccggaagg tgtaaaaccc caggcttcct cttcttgtag tccatctccc agacttgtga    960

ctatggcttt tcattcttca attcatgacg atgcagtggc atgatcatag ctcattgcat   1020

ccttgaaatc ctgggctcag gtgatcctcc cgcctgagcc tcctgagtat ctgggactac   1080

agatgcgtgc caccaagcct ggctaatttt gtctcatgtc ttctaaaaat tattttgtga   1140

agccccttca caaaaaacct taagggaaat ctgatggtgc tcaggaatct aactctccct   1200

aaaccatcct ctttaactgc ttctaaaata tctctgttgg cctttcttag cctttttctg   1260

tttccattca gtgctccaag cgctttttgt ttctaagttg agtgcttggg gtttgacagg   1320

tagtgacgtg tagtttgaca ctgttaactt gttaaataca gtgaaaagtt tgtgagtgaa   1380

gaatgctgag aagattgtaa tgctttgtac aaataaaagt cttgttaaaa aatga        1435


<210>  6215
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  6215

Met Val Pro Val Ser Phe Thr Lys Thr Asp Gly Ile Val Ser Asp Val 
1               5                   10                  15


Pro Tyr Ser Leu Leu Leu Tyr Ser Phe Arg Ile Cys His His Leu Pro 
            20                  25                  30


Glu Gly Val Lys Pro Gln Ala Ser Ser Ser Cys Ser Pro Ser Pro Arg 
        35                  40                  45


Leu Val Thr Met Ala Phe His Ser Ser Ile His Asp Asp Ala Val Ala 
    50                  55                  60


<210>  6216
<211>  2399
<212>  DNA
<213>  Homo sapiens

<400>  6216
gtagctccct gaagcggagg cgaaggggag tttaagcccc agcggcggca atggcggaga     60

ggcccgagga cctaaacctg cccaatgccg tgatcaccag gatcatcaag gaggcgctcc    120

cggacggtgt caacatctcc aaggaggccc ggagcgccat ctcccgcgcc gccagcgtct    180

tcgtgctgta cgccacatcc tggtgagcgg gacagaggca taagggaggc gcggggatac    240

ctggctggga gttgctggct gggagcctac aaaccccaac gattgtgttc tccctcggtg    300

gggacatgtt cacagtcctc tgccagtttt tacaagttct gaagcaaaat aacacaacaa    360

aatcactttg ctttagcttt tttgtgcaga gaagggaagg acttatccct gtcacaccaa    420

aatccataca tgtaagaggc aggctttccc gttccacctc tgggtgctcc ttttcccact    480

cacgccttac aaacaagagg gagtctgaca gcctttctct tctctcagtg ctaacaactt    540

tgcaatgaaa ggaaagcgga agacgctgaa tgccagtgat gtgctctcag ccatggaaga    600

gatggagttc cagcggttcg ttaccccatt gaaagaagct ctggaagcat ataggcggga    660

gcagaaaggc aagaaggagg cctcagagca aaagaagaag gacaaagaca aaaaaacaga    720

ctcggaagag caagacaaga gcagggatga ggacaatgat gaagacgaag aaaggctgga    780

agaagaagaa cagaatgaag aggaagaagt agacaactga aaagggcggg agactgtggc    840

accttggaag gtaccacttg aaatgagacg tgctacgtgt ttctgtgaag cttttccatg    900

ctgggcagag tagtctcagg caaaagtgcc tgaaaagatc agaataaaaa ctgactagaa    960

ataccgtcaa aaccagcact taccaaactc agagcatctg agtagcagaa tcctgttttg   1020

cttcatcaat ctgaaggtta tggccttttg acaagaggga ttctgaacga ctaaattagt   1080

cagtttgctc gcttttgttt acttaaatgt atggttagat ggtttttgat ctgcagtctt   1140

ccctagtccc ccaaataagt aataataact tccatgctgc ctgctgtgtt ccagatcaca   1200

gaggcagcca aggctcagga aaaactgggg ctttgcttat ggtcagccta tgtttgattg   1260

cacagtcttt gacaatagta gcttactaag actgctcaga atgagtaagc tttaggaaac   1320

tactaaaatg ctgtgggaga ataacaaaat ccgttctctc tcttcacttg acagaagcat   1380

taactgaatt ttgtttttca tagacccact tggcccaaaa cctttctata ttgcctgtag   1440

atgatcggcc tgctggtgtg gtagtaatct gatcacagat attcttaaat cagcagtgtg   1500

gaatggtatt agtcaaacat ggtgccagtg tcttttacaa aaacagatgg catagtgtca   1560

gatgtacctt actctctgct actgtacagc tttaggattt gtcatcacct cccggaaggt   1620

gtaaaacccc aggcttcctc ttcttgtagt ccatctccca gacttgtgac tatggctttt   1680

cattcttcaa ttcatgacga gtgccaaact tgattttctc taggcacagc tttctccctc   1740

tgtgcctcct gcttcctttc tctctcctgc ctctcctctg ctccccatcc cactttctca   1800

tctgcctcct tttctcactt ctgtcagtct gtaagctttg ataacctgct taatactcca   1860

aagtgtgagt tcctctgatc tcttgattcc ttagttctaa tctcacgttt tgtttttaag   1920

agatggagtc tctcactctg tggcccaggc tggagtgcag tggcatgatc atagctcatt   1980

gcatccttga aatcctgggc tcaggtgatc ctcccgcctg agcctcctga gtatctggga   2040

ctacagatgc gtgccaccaa gcctggctaa ttttgtctca tgtcttctaa aaattatttt   2100

gtgaagcccc ttcacaaaaa accttaaggg aaatctgatg gtgctcagga atctaactct   2160

ccctaaacca tcctctttaa ctgcttctaa aatatctctg ttggcctttc ttagcctttt   2220

tctgtttcca ttcagtgctc caagcgcttt ttgtttctaa gttgagtgct tggggtttga   2280

caggtagtga cgtgtagttt gacactgtta acttgttaaa tacagtgaaa agtttgtgag   2340

tgaagaatgc tgagaagatt gtaatgcttt gtacaaataa aagtcttgtt aaaaaatga    2399


<210>  6217
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  6217

Met Lys Gly Lys Arg Lys Thr Leu Asn Ala Ser Asp Val Leu Ser Ala 
1               5                   10                  15


Met Glu Glu Met Glu Phe Gln Arg Phe Val Thr Pro Leu Lys Glu Ala 
            20                  25                  30


Leu Glu Ala Tyr Arg Arg Glu Gln Lys Gly Lys Lys Glu Ala Ser Glu 
        35                  40                  45


Gln Lys Lys Lys Asp Lys Asp Lys Lys Thr Asp Ser Glu Glu Gln Asp 
    50                  55                  60


Lys Ser Arg Asp Glu Asp Asn Asp Glu Asp Glu Glu Arg Leu Glu Glu 
65                  70                  75                  80


Glu Glu Gln Asn Glu Glu Glu Glu Val Asp Asn 
                85                  90


<210>  6218
<211>  2018
<212>  DNA
<213>  Homo sapiens

<400>  6218
agaccgtagc gacgcgggaa gtccggacgc agtagctccc tgaagcggag gcgaagggga     60

gtttaagccc cagcggcggc aatggcggag aggcccgagg acctaaacct gcccaatgcc    120

gtgatcacca ggatcatcaa ggaggcgtgc taacaacttt gcaatgaaag gaaagcggaa    180

gacgctgaat gccagtgatg tgctctcagc catggaagag atggagttcc agcggttcgt    240

taccccattg aaagaagctc tggaagcata taggcgggag cagaaaggca agaaggaggc    300

ctcagagcaa aagaagaagg acaaagacaa aaaaacagac tcggaagagc aagacaagag    360

cagggatgag gacaatgatg aagacgaaga aaggctggaa gaagaagaac agaatgaaga    420

ggaagaagta gacaactgaa aagggcggga gactgtggca ccttggaagg taccacttga    480

aatgagacgt gctacgtgtt tctgtgaagc ttttccatgc tgggcagagt agtctcaggc    540

aaaagtgcct gaaaagatca gaataaaaac tgactagaaa taccgtcaaa accagcactt    600

accaaactca gagcatctga gtagcagaat cctgttttgc ttcatcaatc tgaaggttat    660

ggccttttga caagagggat tctgaacgac taaattagtc agtttgctcg cttttgttta    720

cttaaatgta tggttagatg gtttttgatc tgcagtcttc cctagtcccc caaataagta    780

ataataactt ccatgctgcc tgctgtgttc cagatcacag aggcagccaa ggctcaggaa    840

aaactggggc tttgcttatg gtcagcctat gtttgattgc acagtctttg acaatagtag    900

cttactaaga ctgctcagaa tgagtaagct ttaggaaact actaaaatgc tgtgggagaa    960

taacaaaatc cgttctctct cttcacttga cagaagcatt aactgaattt tgtttttcat   1020

agacccactt ggcccaaaac ctttctatat tgcctgtaga tgatcggcct gctggtgtgg   1080

tagtaatctg atcacagata ttcttaaatc agcagtgtgg aatggtatta gtcaaacatg   1140

gtgccagtgt cttttacaaa aacagatggc atagtgtcag atgtacctta ctctctgcta   1200

ctgtacagct ttaggatttg tcatcacctc ccggaaggtg taaaacccca ggcttcctct   1260

tcttgtagtc catctcccag acttgtgact atggcttttc attcttcaat tcatgacgag   1320

tgccaaactt gattttctct aggcacagct ttctccctct gtgcctcctg cttcctttct   1380

ctctcctgcc tctcctctgc tccccatccc actttctcat ctgcctcctt ttctcacttc   1440

tgtcagtctg taagctttga taacctgctt aatactccaa agtgtgagtt cctctgatct   1500

cttgattcct tagttctaat ctcacgtttt gtttttaaga gatggagtct ctcactctgt   1560

ggcccaggct ggagtgcagt ggcatgatca tagctcattg catccttgaa atcctgggct   1620

caggtgatcc tcccgcctga gcctcctgag tatctgggac tacagatgcg tgccaccaag   1680

cctggctaat tttgtctcat gtcttctaaa aattattttg tgaagcccct tcacaaaaaa   1740

ccttaaggga aatctgatgg tgctcaggaa tctaactctc cctaaaccat cctctttaac   1800

tgcttctaaa atatctctgt tggcctttct tagccttttt ctgtttccat tcagtgctcc   1860

aagcgctttt tgtttctaag ttgagtgctt ggggtttgac aggtagtgac gtgtagtttg   1920

acactgttaa cttgttaaat acagtgaaaa gtttgtgagt gaagaatgct gagaagattg   1980

taatgctttg tacaaataaa agtcttgtta aaaaatga                           2018


<210>  6219
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  6219

Met Lys Gly Lys Arg Lys Thr Leu Asn Ala Ser Asp Val Leu Ser Ala 
1               5                   10                  15


Met Glu Glu Met Glu Phe Gln Arg Phe Val Thr Pro Leu Lys Glu Ala 
            20                  25                  30


Leu Glu Ala Tyr Arg Arg Glu Gln Lys Gly Lys Lys Glu Ala Ser Glu 
        35                  40                  45


Gln Lys Lys Lys Asp Lys Asp Lys Lys Thr Asp Ser Glu Glu Gln Asp 
    50                  55                  60


Lys Ser Arg Asp Glu Asp Asn Asp Glu Asp Glu Glu Arg Leu Glu Glu 
65                  70                  75                  80


Glu Glu Gln Asn Glu Glu Glu Glu Val Asp Asn 
                85                  90


<210>  6220
<211>  2316
<212>  DNA
<213>  Homo sapiens

<400>  6220
aaaatccgga tgcgccggta tttgaggcgg aggcggggct gtggggggag gagggaggct     60

atggcgctca gagcactgtg ggacactgta ggccacgtgg ggcggaacgg aaacctcgca    120

gggtcagacc gtagcgacgc gggaagtccg gacgcagtag ctccctgaag cggaggcgaa    180

ggggagttta agccccagcg gcggcaatgg cggagaggcc cgaggaccta aacctgccca    240

atgccgtgat caccaggatc atcaaggagg cggtgagcag ctcggggggg gcggacgaac    300

gggcaggagg gaagcaggtg ctggaacggc agctttgctc acccccggtc tcctcgcagc    360

tcccggacgg tgtcaacatc tccaaggagg cccggagcgc catctcccgc gccgccagcg    420

tcttcgtgct gtacgccaca tcctgtgcta acaactttgc aatgaaagga aagcggaaga    480

cgctgaatgc cagtgatgtg ctctcagcca tggaagagat ggagttccag cggttcgtta    540

ccccattgaa agaagctctg gaagcatata ggcgggagca gaaaggcaag aaggaggcct    600

cagagcaaaa gaagaaggac aaagacaaaa aaacagactc ggaagagcaa gacaagagca    660

gggatgagga caatgatgaa gacgaagaaa ggctggaaga agaagaacag aatgaagagg    720

aagaagtaga caactgaaaa gggcgggaga ctgtggcacc ttggaaggta ccacttgaaa    780

tgagacgtgc tacgtgtttc tgtgaagctt ttccatgctg ggcagagtag tctcaggcaa    840

aagtgcctga aaagatcaga ataaaaactg actagaaata ccgtcaaaac cagcacttac    900

caaactcaga gcatctgagt agcagaatcc tgttttgctt catcaatctg aaggttatgg    960

ccttttgaca agagggattc tgaacgacta aattagtcag tttgctcgct tttgtttact   1020

taaatgtatg gttagatggt ttttgatctg cagtcttccc tagtccccca aataagtaat   1080

aataacttcc atgctgcctg ctgtgttcca gatcacagag gcagccaagg ctcaggaaaa   1140

actggggctt tgcttatggt cagcctatgt ttgattgcac agtctttgac aatagtagct   1200

tactaagact gctcagaatg agtaagcttt aggaaactac taaaatgctg tgggagaata   1260

acaaaatccg ttctctctct tcacttgaca gaagcattaa ctgaattttg tttttcatag   1320

acccacttgg cccaaaacct ttctatattg cctgtagatg atcggcctgc tggtgtggta   1380

gtaatctgat cacagatatt cttaaatcag cagtgtggaa tggtattagt caaacatggt   1440

gccagtgtct tttacaaaaa cagatggcat agtgtcagat gtaccttact ctctgctact   1500

gtacagcttt aggatttgtc atcacctccc ggaaggtgta aaaccccagg cttcctcttc   1560

ttgtagtcca tctcccagac ttgtgactat ggcttttcat tcttcaattc atgacgagtg   1620

ccaaacttga ttttctctag gcacagcttt ctccctctgt gcctcctgct tcctttctct   1680

ctcctgcctc tcctctgctc cccatcccac tttctcatct gcctcctttt ctcacttctg   1740

tcagtctgta agctttgata acctgcttaa tactccaaag tgtgagttcc tctgatctct   1800

tgattcctta gttctaatct cacgttttgt ttttaagaga tggagtctct cactctgtgg   1860

cccaggctgg agtgcagtgg catgatcata gctcattgca tccttgaaat cctgggctca   1920

ggtgatcctc ccgcctgagc ctcctgagta tctgggacta cagatgcgtg ccaccaagcc   1980

tggctaattt tgtctcatgt cttctaaaaa ttattttgtg aagccccttc acaaaaaacc   2040

ttaagggaaa tctgatggtg ctcaggaatc taactctccc taaaccatcc tctttaactg   2100

cttctaaaat atctctgttg gcctttctta gcctttttct gtttccattc agtgctccaa   2160

gcgctttttg tttctaagtt gagtgcttgg ggtttgacag gtagtgacgt gtagtttgac   2220

actgttaact tgttaaatac agtgaaaagt ttgtgagtga agaatgctga gaagattgta   2280

atgctttgta caaataaaag tcttgttaaa aaatga                             2316


<210>  6221
<211>  176
<212>  PRT
<213>  Homo sapiens

<400>  6221

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Val Ser Ser Ser Gly Gly Ala Asp Glu Arg 
            20                  25                  30


Ala Gly Gly Lys Gln Val Leu Glu Arg Gln Leu Cys Ser Pro Pro Val 
        35                  40                  45


Ser Ser Gln Leu Pro Asp Gly Val Asn Ile Ser Lys Glu Ala Arg Ser 
    50                  55                  60


Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala Thr Ser Cys 
65                  70                  75                  80


Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu Asn Ala Ser 
                85                  90                  95


Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg Phe Val Thr 
            100                 105                 110


Pro Leu Lys Glu Ala Leu Glu Ala Tyr Arg Arg Glu Gln Lys Gly Lys 
        115                 120                 125


Lys Glu Ala Ser Glu Gln Lys Lys Lys Asp Lys Asp Lys Lys Thr Asp 
    130                 135                 140


Ser Glu Glu Gln Asp Lys Ser Arg Asp Glu Asp Asn Asp Glu Asp Glu 
145                 150                 155                 160


Glu Arg Leu Glu Glu Glu Glu Gln Asn Glu Glu Glu Glu Val Asp Asn 
                165                 170                 175


<210>  6222
<211>  2245
<212>  DNA
<213>  Homo sapiens

<400>  6222
aaataagttg gtgagaaggt tcccgacgcg gcgatggcga gaagcagaga aatggacctg     60

gggaggggcg gaggctatgg cgctcagagc actgtgggac actgtaggcc acgtggggcg    120

gaacggaaac ctcgcagggt cagaccgtag cgacgcggga agtccggacg cagtagctcc    180

ctgaagcgga ggcgaagggg agtttaagcc ccagcggcgg caatggcgga gaggcccgag    240

gacctaaacc tgcccaatgc cgtgatcacc aggatcatca aggaggcgct cccggacggt    300

gtcaacatct ccaaggaggc ccggagcgcc atctcccgcg ccgccagcgt cttcgtgctg    360

tacgccacat cctgtgctaa caactttgca atgaaaggaa agcggaagac gctgaatgcc    420

agtgatgtgc tctcagccat ggaagagatg gagttccagc ggttcgttac cccattgaaa    480

gaagctctgg aagcatatag gcgggagcag aaaggcaaga aggaggcctc agagcaaaag    540

aagaaggaca aagacaaaaa aacagactcg gaagagcaag acaagagcag ggatgaggac    600

aatgatgaag acgaagaaag gctggaagaa gaagaacaga atgaagagga agaagtagac    660

aactgaaaag ggcgggagac tgtggcacct tggaaggtac cacttgaaat gagacgtgct    720

acgtgtttct gtgaagcttt tccatgctgg gcagagtagt ctcaggcaaa agtgcctgaa    780

aagatcagaa taaaaactga ctagaaatac cgtcaaaacc agcacttacc aaactcagag    840

catctgagta gcagaatcct gttttgcttc atcaatctga aggttatggc cttttgacaa    900

gagggattct gaacgactaa attagtcagt ttgctcgctt ttgtttactt aaatgtatgg    960

ttagatggtt tttgatctgc agtcttccct agtcccccaa ataagtaata ataacttcca   1020

tgctgcctgc tgtgttccag atcacagagg cagccaaggc tcaggaaaaa ctggggcttt   1080

gcttatggtc agcctatgtt tgattgcaca gtctttgaca atagtagctt actaagactg   1140

ctcagaatga gtaagcttta ggaaactact aaaatgctgt gggagaataa caaaatccgt   1200

tctctctctt cacttgacag aagcattaac tgaattttgt ttttcataga cccacttggc   1260

ccaaaacctt tctatattgc ctgtagatga tcggcctgct ggtgtggtag taatctgatc   1320

acagatattc ttaaatcagc agtgtggaat ggtattagtc aaacatggtg ccagtgtctt   1380

ttacaaaaac agatggcata gtgtcagatg taccttactc tctgctactg tacagcttta   1440

ggatttgtca tcacctcccg gaaggtgtaa aaccccaggc ttcctcttct tgtagtccat   1500

ctcccagact tgtgactatg gcttttcatt cttcaattca tgacgagtgc caaacttgat   1560

tttctctagg cacagctttc tccctctgtg cctcctgctt cctttctctc tcctgcctct   1620

cctctgctcc ccatcccact ttctcatctg cctccttttc tcacttctgt cagtctgtaa   1680

gctttgataa cctgcttaat actccaaagt gtgagttcct ctgatctctt gattccttag   1740

ttctaatctc acgttttgtt tttaagagat ggagtctctc actctgtggc ccaggctgga   1800

gtgcagtggc atgatcatag ctcattgcat ccttgaaatc ctgggctcag gtgatcctcc   1860

cgcctgagcc tcctgagtat ctgggactac agatgcgtgc caccaagcct ggctaatttt   1920

gtctcatgtc ttctaaaaat tattttgtga agccccttca caaaaaacct taagggaaat   1980

ctgatggtgc tcaggaatct aactctccct aaaccatcct ctttaactgc ttctaaaata   2040

tctctgttgg cctttcttag cctttttctg tttccattca gtgctccaag cgctttttgt   2100

ttctaagttg agtgcttggg gtttgacagg tagtgacgtg tagtttgaca ctgttaactt   2160

gttaaataca gtgaaaagtt tgtgagtgaa gaatgctgag aagattgtaa tgctttgtac   2220

aaataaaagt cttgttaaaa aatga                                         2245


<210>  6223
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6223

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Leu Pro Asp Gly Val Asn Ile Ser Lys Glu 
            20                  25                  30


Ala Arg Ser Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala 
        35                  40                  45


Thr Ser Cys Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu 
    50                  55                  60


Asn Ala Ser Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg 
65                  70                  75                  80


Phe Val Thr Pro Leu Lys Glu Ala Leu Glu Ala Tyr Arg Arg Glu Gln 
                85                  90                  95


Lys Gly Lys Lys Glu Ala Ser Glu Gln Lys Lys Lys Asp Lys Asp Lys 
            100                 105                 110


Lys Thr Asp Ser Glu Glu Gln Asp Lys Ser Arg Asp Glu Asp Asn Asp 
        115                 120                 125


Glu Asp Glu Glu Arg Leu Glu Glu Glu Glu Gln Asn Glu Glu Glu Glu 
    130                 135                 140


Val Asp Asn 
145


<210>  6224
<211>  2381
<212>  DNA
<213>  Homo sapiens

<400>  6224
aaacggacgg aagctccatt gagccaaata agttggtgag aaggttcccg acgcggcgat     60

ggcgagaagc agagaaatgg acctggggag gggcgtgcgg ggtgcggtag ggttggatgg    120

aagccttggc gggccaaaac cactgcggct tcaaaatccg gatgcgccgg tatttgaggc    180

ggaggcgggg ctgtgggggg aggagggagg ctatggcgct cagagcactg tgggacactg    240

taggccacgt ggggcggaac ggaaacctcg cagggtcaga ccgtagcgac gcgggaagtc    300

cggacgcagt agctccctga agcggaggcg aaggggagtt taagccccag cggcggcaat    360

ggcggagagg cccgaggacc taaacctgcc caatgccgtg atcaccagga tcatcaagga    420

ggcgctcccg gacggtgtca acatctccaa ggaggcccgg agcgccatct cccgcgccgc    480

cagcgtcttc gtgctgtacg ccacatcctg tgctaacaac tttgcaatga aaggaaagcg    540

gaagacgctg aatgccagtg atgtgctctc agccatggaa gagatggagt tccagcggtt    600

cgttacccca ttgaaagaag ctctggaagc atataggcgg gagcagaaag gcaagaagga    660

ggcctcagag caaaagaaga aggacaaaga caaaaaaaca gactcggaag agcaagacaa    720

gagcagggat gaggacaatg atgaagacga agaaaggctg gaagaagaag aacagaatga    780

agaggaagaa gtagacaact gaaaagggcg ggagactgtg gcaccttgga aggtaccact    840

tgaaatgaga cgtgctacgt gtttctgtga agcttttcca tgctgggcag agtagtctca    900

ggcaaaagtg cctgaaaaga tcagaataaa aactgactag aaataccgtc aaaaccagca    960

cttaccaaac tcagagcatc tgagtagcag aatcctgttt tgcttcatca atctgaaggt   1020

tatggccttt tgacaagagg gattctgaac gactaaatta gtcagtttgc tcgcttttgt   1080

ttacttaaat gtatggttag atggtttttg atctgcagtc ttccctagtc ccccaaataa   1140

gtaataataa cttccatgct gcctgctgtg ttccagatca cagaggcagc caaggctcag   1200

gaaaaactgg ggctttgctt atggtcagcc tatgtttgat tgcacagtct ttgacaatag   1260

tagcttacta agactgctca gaatgagtaa gctttaggaa actactaaaa tgctgtggga   1320

gaataacaaa atccgttctc tctcttcact tgacagaagc attaactgaa ttttgttttt   1380

catagaccca cttggcccaa aacctttcta tattgcctgt agatgatcgg cctgctggtg   1440

tggtagtaat ctgatcacag atattcttaa atcagcagtg tggaatggta ttagtcaaac   1500

atggtgccag tgtcttttac aaaaacagat ggcatagtgt cagatgtacc ttactctctg   1560

ctactgtaca gctttaggat ttgtcatcac ctcccggaag gtgtaaaacc ccaggcttcc   1620

tcttcttgta gtccatctcc cagacttgtg actatggctt ttcattcttc aattcatgac   1680

gagtgccaaa cttgattttc tctaggcaca gctttctccc tctgtgcctc ctgcttcctt   1740

tctctctcct gcctctcctc tgctccccat cccactttct catctgcctc cttttctcac   1800

ttctgtcagt ctgtaagctt tgataacctg cttaatactc caaagtgtga gttcctctga   1860

tctcttgatt ccttagttct aatctcacgt tttgttttta agagatggag tctctcactc   1920

tgtggcccag gctggagtgc agtggcatga tcatagctca ttgcatcctt gaaatcctgg   1980

gctcaggtga tcctcccgcc tgagcctcct gagtatctgg gactacagat gcgtgccacc   2040

aagcctggct aattttgtct catgtcttct aaaaattatt ttgtgaagcc ccttcacaaa   2100

aaaccttaag ggaaatctga tggtgctcag gaatctaact ctccctaaac catcctcttt   2160

aactgcttct aaaatatctc tgttggcctt tcttagcctt tttctgtttc cattcagtgc   2220

tccaagcgct ttttgtttct aagttgagtg cttggggttt gacaggtagt gacgtgtagt   2280

ttgacactgt taacttgtta aatacagtga aaagtttgtg agtgaagaat gctgagaaga   2340

ttgtaatgct ttgtacaaat aaaagtcttg ttaaaaaatg a                       2381


<210>  6225
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6225

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Leu Pro Asp Gly Val Asn Ile Ser Lys Glu 
            20                  25                  30


Ala Arg Ser Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala 
        35                  40                  45


Thr Ser Cys Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu 
    50                  55                  60


Asn Ala Ser Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg 
65                  70                  75                  80


Phe Val Thr Pro Leu Lys Glu Ala Leu Glu Ala Tyr Arg Arg Glu Gln 
                85                  90                  95


Lys Gly Lys Lys Glu Ala Ser Glu Gln Lys Lys Lys Asp Lys Asp Lys 
            100                 105                 110


Lys Thr Asp Ser Glu Glu Gln Asp Lys Ser Arg Asp Glu Asp Asn Asp 
        115                 120                 125


Glu Asp Glu Glu Arg Leu Glu Glu Glu Glu Gln Asn Glu Glu Glu Glu 
    130                 135                 140


Val Asp Asn 
145


<210>  6226
<211>  2197
<212>  DNA
<213>  Homo sapiens

<400>  6226
agcagcggcg cagggcacca tgggaaacgg acggaagctc cattgagcca aataagttgg     60

ccacgtgggg cggaacggaa acctcgcagg gtcagaccgt agcgacgcgg gaagtccgga    120

cgcagtagct ccctgaagcg gaggcgaagg ggagtttaag ccccagcggc ggcaatggcg    180

gagaggcccg aggacctaaa cctgcccaat gccgtgatca ccaggatcat caaggaggcg    240

ctcccggacg gtgtcaacat ctccaaggag gcccggagcg ccatctcccg cgccgccagc    300

gtcttcgtgc tgtacgccac atcctgtgct aacaactttg caatgaaagg aaagcggaag    360

acgctgaatg ccagtgatgt gctctcagcc atggaagaga tggagttcca gcggttcgtt    420

accccattga aagaagctct ggaagcatat aggcgggagc agaaaggcaa gaaggaggcc    480

tcagagcaaa agaagaagga caaagacaaa aaaacagact cggaagagca agacaagagc    540

agggatgagg acaatgatga agacgaagaa aggctggaag aagaagaaca gaatgaagag    600

gaagaagtag acaactgaaa agggcgggag actgtggcac cttggaaggt accacttgaa    660

atgagacgtg ctacgtgttt ctgtgaagct tttccatgct gggcagagta gtctcaggca    720

aaagtgcctg aaaagatcag aataaaaact gactagaaat accgtcaaaa ccagcactta    780

ccaaactcag agcatctgag tagcagaatc ctgttttgct tcatcaatct gaaggttatg    840

gccttttgac aagagggatt ctgaacgact aaattagtca gtttgctcgc ttttgtttac    900

ttaaatgtat ggttagatgg tttttgatct gcagtcttcc ctagtccccc aaataagtaa    960

taataacttc catgctgcct gctgtgttcc agatcacaga ggcagccaag gctcaggaaa   1020

aactggggct ttgcttatgg tcagcctatg tttgattgca cagtctttga caatagtagc   1080

ttactaagac tgctcagaat gagtaagctt taggaaacta ctaaaatgct gtgggagaat   1140

aacaaaatcc gttctctctc ttcacttgac agaagcatta actgaatttt gtttttcata   1200

gacccacttg gcccaaaacc tttctatatt gcctgtagat gatcggcctg ctggtgtggt   1260

agtaatctga tcacagatat tcttaaatca gcagtgtgga atggtattag tcaaacatgg   1320

tgccagtgtc ttttacaaaa acagatggca tagtgtcaga tgtaccttac tctctgctac   1380

tgtacagctt taggatttgt catcacctcc cggaaggtgt aaaaccccag gcttcctctt   1440

cttgtagtcc atctcccaga cttgtgacta tggcttttca ttcttcaatt catgacgagt   1500

gccaaacttg attttctcta ggcacagctt tctccctctg tgcctcctgc ttcctttctc   1560

tctcctgcct ctcctctgct ccccatccca ctttctcatc tgcctccttt tctcacttct   1620

gtcagtctgt aagctttgat aacctgctta atactccaaa gtgtgagttc ctctgatctc   1680

ttgattcctt agttctaatc tcacgttttg tttttaagag atggagtctc tcactctgtg   1740

gcccaggctg gagtgcagtg gcatgatcat agctcattgc atccttgaaa tcctgggctc   1800

aggtgatcct cccgcctgag cctcctgagt atctgggact acagatgcgt gccaccaagc   1860

ctggctaatt ttgtctcatg tcttctaaaa attattttgt gaagcccctt cacaaaaaac   1920

cttaagggaa atctgatggt gctcaggaat ctaactctcc ctaaaccatc ctctttaact   1980

gcttctaaaa tatctctgtt ggcctttctt agcctttttc tgtttccatt cagtgctcca   2040

agcgcttttt gtttctaagt tgagtgcttg gggtttgaca ggtagtgacg tgtagtttga   2100

cactgttaac ttgttaaata cagtgaaaag tttgtgagtg aagaatgctg agaagattgt   2160

aatgctttgt acaaataaaa gtcttgttaa aaaatga                            2197


<210>  6227
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6227

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Leu Pro Asp Gly Val Asn Ile Ser Lys Glu 
            20                  25                  30


Ala Arg Ser Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala 
        35                  40                  45


Thr Ser Cys Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu 
    50                  55                  60


Asn Ala Ser Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg 
65                  70                  75                  80


Phe Val Thr Pro Leu Lys Glu Ala Leu Glu Ala Tyr Arg Arg Glu Gln 
                85                  90                  95


Lys Gly Lys Lys Glu Ala Ser Glu Gln Lys Lys Lys Asp Lys Asp Lys 
            100                 105                 110


Lys Thr Asp Ser Glu Glu Gln Asp Lys Ser Arg Asp Glu Asp Asn Asp 
        115                 120                 125


Glu Asp Glu Glu Arg Leu Glu Glu Glu Glu Gln Asn Glu Glu Glu Glu 
    130                 135                 140


Val Asp Asn 
145


<210>  6228
<211>  1232
<212>  DNA
<213>  Homo sapiens

<400>  6228
agcatatagg cgggagcaga aaggcaagaa ggaggcctca gagcaaaaga agaaggacaa     60

agacaaaaaa acagactcgg aagagcaaga caagagcagg gatgaggaca atgatgaaga    120

cgaagaaagg ctggaagaag aagaacagaa tgaagaggaa gaagtagaca actgaaaagg    180

gcgggagact gtggcacctt ggaaggtacc acttgaaatg agacgtgcta cgtgtttctg    240

tgaagctttt ccatgctggg cagagtagtc tcaggcaaaa gtgcctgaaa agatcagaat    300

aaaaactgac tagaaatacc gtcaaaacca gcacttacca aactcagagc atctgagtag    360

cagaatcctg ttttgcttca tcaatctgaa ggttatggcc ttttgacaag agggattctg    420

aacgactaaa ttagtcagtt tgctcgcttt tgtttactta aatgtatggt tagatggttt    480

ttgatctgca gtcttcccta gtcccccaaa taagtaataa taacttccat gctgcctgct    540

gtgttccaga tcacagaggc agccaaggct caggaaaaac tggggctttg cttatggtca    600

gcctatgttt gattgcacag tctttgacaa tagtagctta ctaagactgc tcagaatgag    660

taagctttag gaaactacta aaatgctgtg ggagaataac aaaatccgtt ctctctcttc    720

acttgacaga agcattaact gaattttgtt tttcatagac ccacttggcc caaaaccttt    780

ctatattgcc tgtagatgat cggcctgctg gtgtggtagt aatctgatca cagatattct    840

taaatcagca gtgtggaatg gtattagtca aacatggtgc cagtgtcttt tacaaaaaca    900

gatggcatag tgtcagatgt accttactct ctgctactgt acagctttag gatttgtcat    960

cacctcccgg aaggtgtaaa accccaggct tcctcttctt gtagtccatc tcccagactt   1020

gtgactatgg cttttcattc tttcttagcc tttttctgtt tccattcagt gctccaagcg   1080

ctttttgttt ctaagttgag tgcttggggt ttgacaggta gtgacgtgta gtttgacact   1140

gttaacttgt taaatacagt gaaaagtttg tgagtgaaga atgctgagaa gattgtaatg   1200

ctttgtacaa ataaaagtct tgttaaaaaa tg                                 1232


<210>  6229
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  6229

Met Val Pro Val Ser Phe Thr Lys Thr Asp Gly Ile Val Ser Asp Val 
1               5                   10                  15


Pro Tyr Ser Leu Leu Leu Tyr Ser Phe Arg Ile Cys His His Leu Pro 
            20                  25                  30


Glu Gly Val Lys Pro Gln Ala Ser Ser Ser Cys Ser Pro Ser Pro Arg 
        35                  40                  45


Leu Val Thr Met Ala Phe His Ser Phe Leu Ala Phe Phe Cys Phe His 
    50                  55                  60


Ser Val Leu Gln Ala Leu Phe Val Ser Lys Leu Ser Ala Trp Gly Leu 
65                  70                  75                  80


Thr Gly Ser Asp Val 
                85


<210>  6230
<211>  1890
<212>  DNA
<213>  Homo sapiens

<400>  6230
cacgtggggc ggaacggaaa cctcgcaggg tcagaccgta gcgacgcggg aagtccggac     60

gcagtagctc cctgaagcgg aggcgaaggg gagtttaagc cccagcggcg gcaatggcgg    120

agaggcccga ggacctaaac ctgcccaatg ccgtgatcac caggatcatc aaggaggcgc    180

tcccggacgg tgtcaacatc tccaaggagg cccggagcgc catctcccgc gccgccagcg    240

tcttcgtgct gtacgccaca tcctgtgcta acaactttgc aatgaaagga aagcggaaga    300

cgctgaatgc cagtgatgtg ctctcagcca tggaagagat ggagttccag cggttcgtta    360

ccccattgaa agaaaagaag gacaaagaca aaaaaacaga ctcggaagag caagacaaga    420

gcagggatga ggacaatgat gaagacgaag aaaggctgga agaagaagaa cagaatgaag    480

aggaagaagt agacaactga aaagggcggg agactgtggc accttggaag gtaccacttg    540

aaatgagacg tgctacgtgt ttctgtgaag cttttccatg ctgggcagag tagtctcagg    600

caaaagtgcc tgaaaagatc agaataaaaa ctgactagaa ataccgtcaa aaccagcact    660

taccaaactc agagcatctg agtagcagaa tcctgttttg cttcatcaat ctgaaggtta    720

tggccttttg acaagaggga ttctgaacga ctaaattagt cagtttgctc gcttttgttt    780

acttaaatgt atggttagat ggtttttgat ctgcagtctt ccctagtccc ccaaataagt    840

aataataact tccatgctgc ctgctgtgtt ccagatcaca gaggcagcca aggctcagga    900

aaaactgggg ctttgcttat ggtcagccta tgtttgattg cacagtcttt gacaatagta    960

gcttactaag actgctcaga atgagtaagc tttaggaaac tactaaaatg ctgtgggaga   1020

ataacaaaat ccgttctctc tcttcacttg acagaagcat taactgaatt ttgtttttca   1080

tagacccact tggcccaaaa cctttctata ttgcctgtag atgatcggcc tgctggtgtg   1140

gtagtaatct gatcacagat attcttaaat cagcagtgtg gaatggtatt agtcaaacat   1200

ggtgccagtg tcttttacaa aaacagatgg catagtgtca gatgtacctt actctctgct   1260

actgtacagc tttaggattt gtcatcacct cccggaaggt gtaaaacccc aggcttcctc   1320

ttcttgtagt ccatctccca gacttgtgac tatggctttt cattcttcaa ttcatgacga   1380

gtgccaaact tgattttctc taggcacagc tttctccctc tgtgcctcct gcttcctttc   1440

tctctcctgc ctctcctctg ctccccatcc cactttctca tctgcctcct tttctcactt   1500

ctgtcagtct gtaagctttg ataacctgct taatactcca aagtgtgagt tcctctgatc   1560

tcttgattcc ttagtcttct aaaaattatt ttgtgaagcc ccttcacaaa aaaccttaag   1620

ggaaatctga tggtgctcag gaatctaact ctccctaaac catcctcttt aactgcttct   1680

aaaatatctc tgttggcctt tcttagcctt tttctgtttc cattcagtgc tccaagcgct   1740

ttttgtttct aagttgagtg cttggggttt gacaggtagt gacgtgtagt ttgacactgt   1800

taacttgtta aatacagtga aaagtttgtg agtgaagaat gctgagaaga ttgtaatgct   1860

ttgtacaaat aaaagtcttg ttaaaaaatg                                    1890


<210>  6231
<211>  128
<212>  PRT
<213>  Homo sapiens

<400>  6231

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Leu Pro Asp Gly Val Asn Ile Ser Lys Glu 
            20                  25                  30


Ala Arg Ser Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala 
        35                  40                  45


Thr Ser Cys Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu 
    50                  55                  60


Asn Ala Ser Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg 
65                  70                  75                  80


Phe Val Thr Pro Leu Lys Glu Lys Lys Asp Lys Asp Lys Lys Thr Asp 
                85                  90                  95


Ser Glu Glu Gln Asp Lys Ser Arg Asp Glu Asp Asn Asp Glu Asp Glu 
            100                 105                 110


Glu Arg Leu Glu Glu Glu Glu Gln Asn Glu Glu Glu Glu Val Asp Asn 
        115                 120                 125


<210>  6232
<211>  1125
<212>  DNA
<213>  Homo sapiens

<400>  6232
agcatatagg cgggagcaga aaggcaagaa ggaggcctca gagcaaaaga agaaggacaa     60

agacaaaaaa acagactcgg aagagcaaga caagagcagg gatgaggaca atgatgaaga    120

cgaagaaagg ctggaagaag aagaacagaa tgaagaggaa gaagtagaca actgaaaagg    180

gcgggagact gtggcacctt ggaaggtacc acttgaaatg agacgtgcta cgtgtttctg    240

tgaagctttt ccatgctggg cagagtagtc tcaggcaaaa gtgcctgaaa agatcagaat    300

aaaaactgac tagaaatacc gtcaaaacca gcacttacca aactcagagc atctgagtag    360

cagaatcctg ttttgcttca tcaatctgaa ggttatggcc ttttgacaag agggattctg    420

aacgactaaa ttagtcagtt tgctcgcttt tgtttactta aatgtatggt tagatggttt    480

ttgatctgca gtcttcccta gtcccccaaa taagtaataa taacttccat gctgcctgct    540

gtgttccaga tcacagaggc agccaaggct caggaaaaac tggggctttg cttatggtca    600

gcctatgttt gattgcacag tctttgacaa tagtagctta ctaagactgc tcagaatgag    660

taagctttag gaaactacta aaatgctgtg ggagaataac aaaatccgtt ctctctcttc    720

acttgacaga agcattaact gaattttgtt tttcatagac ccacttggcc caaaaccttt    780

ctatattgcc tgtagatgat cggcctgctg gtgtggtagt aatctgatca cagatattct    840

taaatcagca gtgtggaatg gtattagtca aacatggtgc cagtgtcttt tacaaaaaca    900

gatggcatag tgtcagatgt accttactct ctgctactgt acagctttag gatttgtcat    960

cacctcccgg aaggtgtaaa accccaggct tctaagttga gtgcttgggg tttgacaggt   1020

agtgacgtgt agtttgacac tgttaacttg ttaaatacag tgaaaagttt gtgagtgaag   1080

aatgctgaga agattgtaat gctttgtaca aataaaagtc ttgtt                   1125


<210>  6233
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  6233

Met Val Pro Val Ser Phe Thr Lys Thr Asp Gly Ile Val Ser Asp Val 
1               5                   10                  15


Pro Tyr Ser Leu Leu Leu Tyr Ser Phe Arg Ile Cys His His Leu Pro 
            20                  25                  30


Glu Gly Val Lys Pro Gln Ala Ser Lys Leu Ser Ala Trp Gly Leu Thr 
        35                  40                  45


Gly Ser Asp Val 
    50


<210>  6234
<211>  646
<212>  DNA
<213>  Homo sapiens

<400>  6234
agcagcggcg cagggcacca tgggaaacgg acggaagctc cattgagcca aataagttgg     60

tgagaaggtt cccgacgcgg cgatggcgag aagcagagaa atggacctgg ggaggggcgt    120

gcggggtgcg gtagggttgg atggaagcct tggcgggcca aaaccactgc ggcttcaaaa    180

tccggatgcg ccggtatttg aggcggaggc ggggctgtgg ggggaggagg gaggctatgg    240

cgctcagagc actgtgggac actgtaggcc acgtggggcg gaacggaaac ctcgcagggt    300

cagaccgtag cgacgcggga agtccggacg cagtagctcc ctgaagcgga ggcgaagggg    360

agtttaagcc ccagcggcgg caatggcgga gaggcccgag gacctaaacc tgcccaatgc    420

cgtgatcacc aggatcatca aggaggcgct cccggacggt gtcaacatct ccaaggaggc    480

ccggagcgcc atctcccgcg ccgccagcgt cttcgtgctg tacgccacat cctgtgctaa    540

caactttgca atgaaaggaa agcggaagac gctgaatgcc agtgatgtgc tctcagccat    600

ggaagagatg gagttccagc ggttcgttac cccattgaaa gaagct                   646


<210>  6235
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  6235

Met Ala Glu Arg Pro Glu Asp Leu Asn Leu Pro Asn Ala Val Ile Thr 
1               5                   10                  15


Arg Ile Ile Lys Glu Ala Leu Pro Asp Gly Val Asn Ile Ser Lys Glu 
            20                  25                  30


Ala Arg Ser Ala Ile Ser Arg Ala Ala Ser Val Phe Val Leu Tyr Ala 
        35                  40                  45


Thr Ser Cys Ala Asn Asn Phe Ala Met Lys Gly Lys Arg Lys Thr Leu 
    50                  55                  60


Asn Ala Ser Asp Val Leu Ser Ala Met Glu Glu Met Glu Phe Gln Arg 
65                  70                  75                  80


Phe Val Thr Pro Leu Lys Glu 
                85


<210>  6236
<211>  1007
<212>  DNA
<213>  Homo sapiens

<400>  6236
gcagtggttt tggcccgcca aggcttccat ccaaccctac cgcaccccgc acgcccctcc     60

ccaggtccat ttctctgctt ctcgccatcg ccgcgtcggg aaccttctca ccaacttatt    120

tggctcaatg gagcttccgt ccgtttccca tggtgccctg cgccgctgct gggtgacggc    180

gcggccgggc gcagcgcgtg ggagacgaag gcgtggctga ctcggcgggg cggatccctt    240

taggacccga ggcaggctct gggcccgccg ggtccgttaa tctcaccgcg ccgcaagggg    300

ccacgtttta ccacttgatt tagcaaccct aagcggtttg gaatctgctt tgctctcaca    360

ggacctcagc ccgtcgtgat cagattctcc cactttcttt tttctttcct ggaatggagt    420

gggcagtctt tttccatctc taccgaagtt gatgttcatt tttaatcttt tcgcccctca    480

cgcttttgta ataatgagca ctagaatgct gcagggttgg cctttggcct aaaccatttc    540

tagctatgga cttgccagat gagagccagt gggacgaaac cacctgtggc ttggctgttt    600

gtcagcaccc acaatgctgg gcaactatcc gccgcattga gaggggccat cctcgaatcc    660

tcggctcatc ctgcaaaact cccctggatg ctgaagtttc cagtgttgaa tttgaatgag    720

acgcaacttc cctgccctga agatgttaga aatatggttg tattgtggat cccagaagaa    780

acagagatac atgtgagcca gcatgggaag aagaaaagaa agaactcggc agtgaaaagc    840

aagtcatttc tgggtctctc tggaaatcag tccgcaggaa cacgagtagg aacaccaggg    900

atgatcgtgc ctcccccaac cccagtgcaa ttgtctgaac aattcagttc agatttccta    960

cctctctggg ctcaatccga agcgttacct caggatctac tgaagga                 1007


<210>  6237
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  6237

Met Arg Ala Ser Gly Thr Lys Pro Pro Val Ala Trp Leu Phe Val Ser 
1               5                   10                  15


Thr His Asn Ala Gly Gln Leu Ser Ala Ala Leu Arg Gly Ala Ile Leu 
            20                  25                  30


Glu Ser Ser Ala His Pro Ala Lys Leu Pro Trp Met Leu Lys Phe Pro 
        35                  40                  45


Val Leu Asn Leu Asn Glu Thr Gln Leu Pro Cys Pro Glu Asp Val Arg 
    50                  55                  60


Asn Met Val Val Leu Trp Ile Pro Glu Glu Thr Glu Ile His Val Ser 
65                  70                  75                  80


Gln His Gly Lys Lys Lys Arg Lys Asn Ser Ala Val Lys Ser Lys Ser 
                85                  90                  95


Phe Leu Gly Leu Ser Gly Asn Gln Ser Ala Gly Thr Arg Val Gly Thr 
            100                 105                 110


Pro Gly Met Ile Val Pro Pro Pro Thr Pro Val Gln Leu Ser Glu Gln 
        115                 120                 125


Phe Ser Ser Asp Phe Leu Pro Leu Trp Ala Gln Ser Glu Ala Leu Pro 
    130                 135                 140


Gln Asp Leu Leu 
145


<210>  6238
<211>  2142
<212>  DNA
<213>  Homo sapiens

<400>  6238
gcagtggttt tggcccgcca aggcttccat ccaaccctac cgcaccccgc acgcccctcc     60

ccaggtccat ttctctgctt ctcgccatcg ccgcgtcggg aaccttctca ccaacttatt    120

tggctcaatg gagcttccgt ccgtttccca tggtgccctg cgccgctgct gggtgacggc    180

gcggccgggc gcagcgcgtg ggagacgaag gcgtggctga ctcggcgggg cggatccctt    240

taggacccga ggcaggctct gggcccgccg ggtccgttaa tctcaccgcg ccgcaagggg    300

ccacgtttta ccacttgatt tagcaaccct aagcggtttg gaatctgctt tgctctcaca    360

ggacctcagc ccgtcgtgat cagattctcc cactttcttt tttctttcct ggaatggagt    420

gggcagtctt tttccatctc taccgaagtt gatgttcatt tttaatcttt tcgcccctca    480

cgcttttgta ataatgagca ctagaatgct gcagggttgg cctttggcct aaaccatttc    540

tagctatgga cttgccagat gagagccagt gggacgaaac cacctgtggc ttggctgttt    600

gtcagcaccc acaatgctgg gcaactatcc gccgcattga gaggggccat cctcgaatcc    660

tcggctcatc ctgcaaaact cccctggatg ctgaagataa actcccagtg ctcaccgtgg    720

tagacatctt agattccggc tttgcagctc atcatttacc agaatgtacc tttactaagg    780

cccattcttt attgtctcag agttcaaagt tttactccaa atttcatggc aggcctccga    840

agggtttacc tgacaaaagt ttgatcaact gtactaacag acttcccaaa tttccagtgt    900

tgaatttgaa tgagacgcaa cttccctgcc ctgaagatgt tagaaatatg gttgtattgt    960

ggatcccaga agaaacagag atacatgtga gccagcatgg gaagaagaaa agaaagaact   1020

cggcagtgaa aagcaagtca tttctgggtc tctctggaaa tcagtccgca ggaacacgag   1080

taggaacacc agggatgatc gtgcctcccc caaccccagt gcaattgtct gaacaattca   1140

gttcagattt cctacctctc tgggctcaat ccgaagcgtt acctcaggat ctactgaagg   1200

aacttttgcc aggtggaaag caaaccatgc tctgtccaga gatgaagata aaattggcca   1260

tgatgaaaaa gaatcttccc ttggaaaaga accgacctga cagtgtgatt tcttctaaga   1320

tgtttctatc tatacaccgc ctcaccctgg aaagaccagc actgcgatat cctgaacgtt   1380

tgaagaaatt acataacctg aagacagaag gttacaggaa acagcagcag cggcagcagc   1440

agcagcagca gcaacagaag aaggtgaaaa cacctattaa gaaacaggag gctaaaaaga   1500

aagccaagag tgatccaggg atccagagca cttcacataa acatccagtt accaccgttc   1560

atgaccgtct ctatggttac agaactctgc caggtcagaa cagtgacatg aagcagcagc   1620

agcagatgga aaaaggaacc acttcgaaac aggattccac ggagagacca aagatgaact   1680

actatgacca tgcggatttc caccacagtg taaaaagtcc tgaattgtat gaaacagaac   1740

ccactaacaa ggacattagt gctccagtgg acgctgtgcc agaagcccag gctgccaggc   1800

aaaagaagat ctcctttaac ttttcagaaa ttatggctag cacaggctgg aactctgagc   1860

tcaaactact taggattctt caggacactg atgatgagga tgaggaggac cagtcctctg   1920

gggcagagtg agaagcctct ggaggaatag actgaaggca tcccctgggg cagccgtgtt   1980

ccaaagcggg atggctggta tcctgagggc agcaacgttt cacataaggg caagaggaga   2040

ggggcttctg ctctctggag cctttaccag ggcctgagct ctgagcttag ggattccatt   2100

ttctttgttc acctctactt gcctctaaaa taaatgtagg ag                      2142


<210>  6239
<211>  461
<212>  PRT
<213>  Homo sapiens

<400>  6239

Met Asp Leu Pro Asp Glu Ser Gln Trp Asp Glu Thr Thr Cys Gly Leu 
1               5                   10                  15


Ala Val Cys Gln His Pro Gln Cys Trp Ala Thr Ile Arg Arg Ile Glu 
            20                  25                  30


Arg Gly His Pro Arg Ile Leu Gly Ser Ser Cys Lys Thr Pro Leu Asp 
        35                  40                  45


Ala Glu Asp Lys Leu Pro Val Leu Thr Val Val Asp Ile Leu Asp Ser 
    50                  55                  60


Gly Phe Ala Ala His His Leu Pro Glu Cys Thr Phe Thr Lys Ala His 
65                  70                  75                  80


Ser Leu Leu Ser Gln Ser Ser Lys Phe Tyr Ser Lys Phe His Gly Arg 
                85                  90                  95


Pro Pro Lys Gly Leu Pro Asp Lys Ser Leu Ile Asn Cys Thr Asn Arg 
            100                 105                 110


Leu Pro Lys Phe Pro Val Leu Asn Leu Asn Glu Thr Gln Leu Pro Cys 
        115                 120                 125


Pro Glu Asp Val Arg Asn Met Val Val Leu Trp Ile Pro Glu Glu Thr 
    130                 135                 140


Glu Ile His Val Ser Gln His Gly Lys Lys Lys Arg Lys Asn Ser Ala 
145                 150                 155                 160


Val Lys Ser Lys Ser Phe Leu Gly Leu Ser Gly Asn Gln Ser Ala Gly 
                165                 170                 175


Thr Arg Val Gly Thr Pro Gly Met Ile Val Pro Pro Pro Thr Pro Val 
            180                 185                 190


Gln Leu Ser Glu Gln Phe Ser Ser Asp Phe Leu Pro Leu Trp Ala Gln 
        195                 200                 205


Ser Glu Ala Leu Pro Gln Asp Leu Leu Lys Glu Leu Leu Pro Gly Gly 
    210                 215                 220


Lys Gln Thr Met Leu Cys Pro Glu Met Lys Ile Lys Leu Ala Met Met 
225                 230                 235                 240


Lys Lys Asn Leu Pro Leu Glu Lys Asn Arg Pro Asp Ser Val Ile Ser 
                245                 250                 255


Ser Lys Met Phe Leu Ser Ile His Arg Leu Thr Leu Glu Arg Pro Ala 
            260                 265                 270


Leu Arg Tyr Pro Glu Arg Leu Lys Lys Leu His Asn Leu Lys Thr Glu 
        275                 280                 285


Gly Tyr Arg Lys Gln Gln Gln Arg Gln Gln Gln Gln Gln Gln Gln Gln 
    290                 295                 300


Lys Lys Val Lys Thr Pro Ile Lys Lys Gln Glu Ala Lys Lys Lys Ala 
305                 310                 315                 320


Lys Ser Asp Pro Gly Ile Gln Ser Thr Ser His Lys His Pro Val Thr 
                325                 330                 335


Thr Val His Asp Arg Leu Tyr Gly Tyr Arg Thr Leu Pro Gly Gln Asn 
            340                 345                 350


Ser Asp Met Lys Gln Gln Gln Gln Met Glu Lys Gly Thr Thr Ser Lys 
        355                 360                 365


Gln Asp Ser Thr Glu Arg Pro Lys Met Asn Tyr Tyr Asp His Ala Asp 
    370                 375                 380


Phe His His Ser Val Lys Ser Pro Glu Leu Tyr Glu Thr Glu Pro Thr 
385                 390                 395                 400


Asn Lys Asp Ile Ser Ala Pro Val Asp Ala Val Pro Glu Ala Gln Ala 
                405                 410                 415


Ala Arg Gln Lys Lys Ile Ser Phe Asn Phe Ser Glu Ile Met Ala Ser 
            420                 425                 430


Thr Gly Trp Asn Ser Glu Leu Lys Leu Leu Arg Ile Leu Gln Asp Thr 
        435                 440                 445


Asp Asp Glu Asp Glu Glu Asp Gln Ser Ser Gly Ala Glu 
    450                 455                 460


<210>  6240
<211>  2077
<212>  DNA
<213>  Homo sapiens

<400>  6240
agacgaaggc gtggctgact cggcggggcg gatcccttta ggacccgagg caggctctgg     60

gcccgccggg tccgttaatc tcaccgcgcc gcaaggggcc acgttttacc acttgattta    120

gcaaccctaa gcggtttgga atctgctttg ctctcacagg acctcagccc gtcgtgatca    180

gattctccca ctttcttttt tctttcctgg aatggagtgg gcagtctttt tccatctcta    240

ccgaagttga tgttcatttt taatcttttc gcccctcacg cttttgtaat aatggtacta    300

agactgagtg ttatttagat tttattgttg ttgtttgtgt ttaacgcgaa ctatttaggc    360

agcccaggga taatgctggc catatagaga tgcgcctgat taggtctcag gagtcaattc    420

ggactgggca gagcactaga atgctgcagg gttggccttt ggcctaaacc atttctagct    480

atggacttgc cagatgagag ccagtgggac gaaaccacct gtggcttggc tgtttgtcag    540

cacccacaat gctgggcaac tatccgccgc attgagaggg gccatcctcg aatcctcggc    600

tcatcctgca aaactcccct ggatgctgaa gataaactcc cagtgctcac cgtggtagac    660

atcttagatt ccggctttgc agctcatcat ttaccagaat gtacctttac taaggcccat    720

tctttattgt ctcagagttc aaagttttac tccaaatttc atggcaggcc tccgaagggt    780

ttacctgaca aaagtttgat caactgtact aacagacttc ccaaatttcc agtgttgaat    840

ttgaatgaga cgcaacttcc ctgccctgaa gatgttagaa atatggttgt attgtggatc    900

ccagaagaaa cagagataca tgtgagccag catgggaaga agaaaagaaa gaactcggca    960

gtgaaaagca agtcatttct gggtctctct ggaaatcagt ccgcaggaac acgagtagga   1020

acaccaggga tgatcgtgcc tcccccaacc ccagtgcaat tgtctgaaca attcagttca   1080

gatttcctac ctctctgggc tcaatccgaa gcgttacctc aggatctact gaaggaactt   1140

ttgccaggtg gaaagcaaac catgctctgt ccagagatga agataaaatt ggccatgatg   1200

aaaaagaatc ttcccttgga aaagaaccga cctgacagtg tgatttcttc taagatgttt   1260

ctatctatac accgcctcac cctggaaaga ccagcactgc gatatcctga acgtttgaag   1320

aaattacata acctgaagac agaaggttac aggaaacagc agcagcggca gcagcagcag   1380

cagcagcaac agaagaaggt gaaaacacct attaagaaac aggaggctaa aaagaaagcc   1440

aagagtgatc cagggatcca gagcacttca cataaacatc cagttaccac cgttcatgac   1500

cgtctctatg gttacagaac tctgccaggt cagaacagtg acatgaagca gcagcagcag   1560

atggaaaaag gaaccacttc gaaacaggat tccacggaga gaccaaagat gaactactat   1620

gaccatgcgg atttccacca cagtgtaaaa agtcctgaat tgtatgaaac agaacccact   1680

aacaaggaca ttagtgctcc agtggacgct gtgccagaag cccaggctgc caggcaaaag   1740

aagatctcct ttaacttttc agaaattatg gctagcacag gctggaactc tgagctcaaa   1800

ctacttagga ttcttcagga cactgatgat gaggatgagg aggaccagtc ctctggggca   1860

gagtgagaag cctctggagg aatagactga aggcatcccc tggggcagcc gtgttccaaa   1920

gcgggatggc tggtatcctg agggcagcaa cgtttcacat aagggcaaga ggagaggggc   1980

ttctgctctc tggagccttt accagggcct gagctctgag cttagggatt ccattttctt   2040

tgttcacctc tacttgcctc taaaataaat gtaggag                            2077


<210>  6241
<211>  461
<212>  PRT
<213>  Homo sapiens

<400>  6241

Met Asp Leu Pro Asp Glu Ser Gln Trp Asp Glu Thr Thr Cys Gly Leu 
1               5                   10                  15


Ala Val Cys Gln His Pro Gln Cys Trp Ala Thr Ile Arg Arg Ile Glu 
            20                  25                  30


Arg Gly His Pro Arg Ile Leu Gly Ser Ser Cys Lys Thr Pro Leu Asp 
        35                  40                  45


Ala Glu Asp Lys Leu Pro Val Leu Thr Val Val Asp Ile Leu Asp Ser 
    50                  55                  60


Gly Phe Ala Ala His His Leu Pro Glu Cys Thr Phe Thr Lys Ala His 
65                  70                  75                  80


Ser Leu Leu Ser Gln Ser Ser Lys Phe Tyr Ser Lys Phe His Gly Arg 
                85                  90                  95


Pro Pro Lys Gly Leu Pro Asp Lys Ser Leu Ile Asn Cys Thr Asn Arg 
            100                 105                 110


Leu Pro Lys Phe Pro Val Leu Asn Leu Asn Glu Thr Gln Leu Pro Cys 
        115                 120                 125


Pro Glu Asp Val Arg Asn Met Val Val Leu Trp Ile Pro Glu Glu Thr 
    130                 135                 140


Glu Ile His Val Ser Gln His Gly Lys Lys Lys Arg Lys Asn Ser Ala 
145                 150                 155                 160


Val Lys Ser Lys Ser Phe Leu Gly Leu Ser Gly Asn Gln Ser Ala Gly 
                165                 170                 175


Thr Arg Val Gly Thr Pro Gly Met Ile Val Pro Pro Pro Thr Pro Val 
            180                 185                 190


Gln Leu Ser Glu Gln Phe Ser Ser Asp Phe Leu Pro Leu Trp Ala Gln 
        195                 200                 205


Ser Glu Ala Leu Pro Gln Asp Leu Leu Lys Glu Leu Leu Pro Gly Gly 
    210                 215                 220


Lys Gln Thr Met Leu Cys Pro Glu Met Lys Ile Lys Leu Ala Met Met 
225                 230                 235                 240


Lys Lys Asn Leu Pro Leu Glu Lys Asn Arg Pro Asp Ser Val Ile Ser 
                245                 250                 255


Ser Lys Met Phe Leu Ser Ile His Arg Leu Thr Leu Glu Arg Pro Ala 
            260                 265                 270


Leu Arg Tyr Pro Glu Arg Leu Lys Lys Leu His Asn Leu Lys Thr Glu 
        275                 280                 285


Gly Tyr Arg Lys Gln Gln Gln Arg Gln Gln Gln Gln Gln Gln Gln Gln 
    290                 295                 300


Lys Lys Val Lys Thr Pro Ile Lys Lys Gln Glu Ala Lys Lys Lys Ala 
305                 310                 315                 320


Lys Ser Asp Pro Gly Ile Gln Ser Thr Ser His Lys His Pro Val Thr 
                325                 330                 335


Thr Val His Asp Arg Leu Tyr Gly Tyr Arg Thr Leu Pro Gly Gln Asn 
            340                 345                 350


Ser Asp Met Lys Gln Gln Gln Gln Met Glu Lys Gly Thr Thr Ser Lys 
        355                 360                 365


Gln Asp Ser Thr Glu Arg Pro Lys Met Asn Tyr Tyr Asp His Ala Asp 
    370                 375                 380


Phe His His Ser Val Lys Ser Pro Glu Leu Tyr Glu Thr Glu Pro Thr 
385                 390                 395                 400


Asn Lys Asp Ile Ser Ala Pro Val Asp Ala Val Pro Glu Ala Gln Ala 
                405                 410                 415


Ala Arg Gln Lys Lys Ile Ser Phe Asn Phe Ser Glu Ile Met Ala Ser 
            420                 425                 430


Thr Gly Trp Asn Ser Glu Leu Lys Leu Leu Arg Ile Leu Gln Asp Thr 
        435                 440                 445


Asp Asp Glu Asp Glu Glu Asp Gln Ser Ser Gly Ala Glu 
    450                 455                 460


<210>  6242
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  6242
attaactaat ttttataatg accctgtgaa ataagcttat cctcatttta cagtggaggc     60

aacaggctca gactggttaa gtcccaggtc actcagctat taaatagcca attaggagac    120

ctgaagtcct gctctcaaac tcttgccatt ctactttatg ctgagctatt ttcatacttg    180

cttgttatcc aatctttaat tattttgtgg ccatcattta cctatatagg ttcaatagaa    240

atattttata ctgtgagttc aaattaacat ctggactgta tggctaatgt ataatactcc    300

ctaattatgt agctgttgat tttccagagc actagaatgc tgcagggttg gcctttggcc    360

taaaccattt ctagctatgg acttgccaga tgagagccag tgggacgaaa ccacctgtgg    420

cttggctgtt tgtcagcacc cacaatgctg ggcaactatc cgccgcattg agaggggcca    480

tcctcgaatc ctcggctcat cctgcaaaac tcccctggat gctgaagata aactcccagt    540

gctcacc                                                              547


<210>  6243
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  6243

Met Asp Leu Pro Asp Glu Ser Gln Trp Asp Glu Thr Thr Cys Gly Leu 
1               5                   10                  15


Ala Val Cys Gln His Pro Gln Cys Trp Ala Thr Ile Arg Arg Ile Glu 
            20                  25                  30


Arg Gly His Pro Arg Ile Leu Gly Ser Ser Cys Lys Thr Pro Leu Asp 
        35                  40                  45


Ala Glu Asp Lys Leu Pro Val Leu 
    50                  55


<210>  6244
<211>  594
<212>  DNA
<213>  Homo sapiens

<400>  6244
attgtgccta gaacatagag caggaatgga agagtggtca gagatgaggc tggggagctg     60

cagtagaaac aggaagcagg agtctgtgtc atgtaggact tcataaagca ggctgagtgt    120

tagctggaga gaagagtagg ctatgaattc tgtttgatgg aacaaatagt tgtgaagtat    180

ttgcagtgtg caatgtctgt taaggagctg ttccgggaaa aacaaacaaa acttaaggat    240

atggtgagat cctacattca tttgtctttt gtatttctgt tttatgtgtg gaactcattt    300

tttaggcctc cgaagggttt acctgacaaa agtttgatca actgtactaa cagacttccc    360

aaatttccag tgttgaattt gaatgagacg caacttccct gccctgaaga tgttagaaat    420

atggttgtat tgtggatccc agaagaaaca gagatacatg tgagccagca tgggaagaag    480

aaaagaaaga actcggcagt gaaaagcaag tcatttctgg gtctctctgg aaatcagtcc    540

gcaggaacac gagtaggaac accagggatg atcgtgcctc ccccaacccc agtg          594


<210>  6245
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  6245

Met Glu Gln Ile Val Val Lys Tyr Leu Gln Cys Ala Met Ser Val Lys 
1               5                   10                  15


Glu Leu Phe Arg Glu Lys Gln Thr Lys Leu Lys Asp Met Val Arg Ser 
            20                  25                  30


Tyr Ile His Leu Ser Phe Val Phe Leu Phe Tyr Val Trp Asn Ser Phe 
        35                  40                  45


Phe Arg Pro Pro Lys Gly Leu Pro Asp Lys Ser Leu Ile Asn Cys Thr 
    50                  55                  60


Asn Arg Leu Pro Lys Phe Pro Val Leu Asn Leu Asn Glu Thr Gln Leu 
65                  70                  75                  80


Pro Cys Pro Glu Asp Val Arg Asn Met Val Val Leu Trp Ile Pro Glu 
                85                  90                  95


Glu Thr Glu Ile His Val Ser Gln His Gly Lys Lys Lys Arg Lys Asn 
            100                 105                 110


Ser Ala Val Lys Ser Lys Ser Phe Leu Gly Leu Ser Gly Asn Gln Ser 
        115                 120                 125


Ala Gly Thr Arg Val Gly Thr Pro Gly Met Ile Val Pro Pro Pro Thr 
    130                 135                 140


Pro 
145


<210>  6246
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  6246
ggttacagaa ctctgccagg tcagaacagt gacatgaagc agcagcagca gatggaaaaa     60

ggaaccactt cgaaacaggt cctgaattgt atgaaacaga acccactaac aaggacatta    120

gtgctccagt ggacgctgtg ccagaagccc aggctgccag gcaaaagaag atctccttta    180

acttttcaga aattatggct agcacaggct ggaactctga gctcaaacta cttaggattc    240

ttcaggacac tgatgatgag gatgaggagg accagtcctc tggggcagag tgagaagcct    300

ctggaggaat agactgaagg catcccctgg ggcagccgtg ttccaaagcg ggatggctgg    360

tatcctgagg gcagcaacgt ttcacataag ggcaagagga gaggggcttc tgctctctgg    420

agcctttacc agggcctgag ctctgagctt agggattcca ttttctttgt tcacctctac    480

ttgcctctaa aataaatgta ggagaaaaat ccccagcctt tttaaattta gattatttcc    540

tttccattag ggtcagaata attttggtga ttaaacacaa ctgcttttc                589


<210>  6247
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6247

Met Lys Gln Gln Gln Gln Met Glu Lys Gly Thr Thr Ser Lys Gln Val 
1               5                   10                  15


Leu Asn Cys Met Lys Gln Asn Pro Leu Thr Arg Thr Leu Val Leu Gln 
            20                  25                  30


Trp Thr Leu Cys Gln Lys Pro Arg Leu Pro Gly Lys Arg Arg Ser Pro 
        35                  40                  45


Leu Thr Phe Gln Lys Leu Trp Leu Ala Gln Ala Gly Thr Leu Ser Ser 
    50                  55                  60


Asn Tyr Leu Gly Phe Phe Arg Thr Leu Met Met Arg Met Arg Arg Thr 
65                  70                  75                  80


Ser Pro Leu Gly Gln Ser Glu Lys Pro Leu Glu Glu 
                85                  90


<210>  6248
<211>  4444
<212>  DNA
<213>  Homo sapiens

<400>  6248
agaactttgg ctcagcctgt cttcatccac tgtatcctga cacctctcct actccttctc     60

tttaatgtac agctgagact gggataccct tagactgaaa ggaaggacac ggctatgtag    120

aaaagaattg actgaagggg aggagtactc gtgaacccct tgcttcagcc tcccaatgtt    180

ctgagagagg aggagccagg cgcagtggct catgcctgta atcccagcac tttgggaggt    240

tgagatgggc agatcgcaag gtcaggagat cgagaccatc ctggctaaca ggtctgccac    300

gtctctgtgc tcagtgtcct ctctacatcc tgtggcttga gcctgagctt gcccatattc    360

cctggctgga tggagtggct aagccctgat atcgctctgc ccagaagaga tgagtggact    420

caaacttctc cagccaggaa gaggatcacg catgccaaag tccagggtgc aggtcagctg    480

aggctgtcca ttgatgccca ggaccgggtt ctgctgcttc acattataga aggtaaaggc    540

ctgatcagca aacagcctgg cacctgtgat ccgtatgtga agatttcttt gatccctgaa    600

gatagtagac tacgccacca gaagacgcag accgttccag actgcagaga cccggctttc    660

cacgagcact tcttctttcc tgtccaagag gaggatgatc agaagcgtct cttggttact    720

gtgtggaaca gggccagcca gtccagacag agtggactca ttggctgcat gagctttggg    780

gtgaagtctc tcctgactcc agacaaggag atcagtggtt ggtactacct cctaggggag    840

cacctgggcc ggaccaagca cttgaaggtg gccaggcggc gactgcggcc gctgagagac    900

ccgctgctga gaatgccagg aggtggggac actgagaatg ggaagaaact aaagatcacc    960

atcccgaggg gaaaggacgg ctttggcttc accatctgct gcgactctcc agttcgagtc   1020

caggccgtgg attccggggg tccggcggaa cgggcagggc tgcagcagct ggacacggtg   1080

ctgcagctga atgagaggcc tgtggagcac tggaaatgtg tggagctggc ccacgagatc   1140

cggagctgcc ccagtgagat catcctactc gtgtggcgca tggtccccca ggtcaagcca   1200

ggaccagatg gcggggtcct gcggcgggcc tcctgcaagt cgacacatga cctccagtca   1260

ccccccaaca aacgggagaa gaactgcacc catggggtcc aggcacggcc tgagcagcgc   1320

cacagctgcc acctggtatg tgacagctct gatgggctgc tgctcggcgg ctgggagcgc   1380

tacaccgagg tggccaagcg cgggggccag cacaccctgc ctgcactgtc ccgtgccact   1440

gcccccaccg accccaacta catcatcctg gccccgctga atcctgggag ccagctgctc   1500

cggcctgtgt accaggagga taccatcccc gaagaatcag ggagtcccag taaagggaag   1560

tcctacacag gcctggggaa gaagtcccgg ctgatgaaga cagtgcagac catgaagggc   1620

cacgggaact accaaaactg cccggttgtg aggccgcatg ccacgcactc aagctatggc   1680

acctacgtca ccctggcccc caaagtcctg gtgttccctg tctttgttca gcctctagat   1740

ctctgtaatc ctgcccggac cctcctgctg tcagaggagc tgctgctgta tgaagggagg   1800

aacaaggctg ccgaggtgac actgtttgcc tattcggacc tgctgctctt caccaaggag   1860

gacgagcctg gccgctgcga cgtcctgagg aaccccctct acctccagag tgtgaagctg   1920

caggaaggtt cttcagaaga cctgaaattc tgcgtgctct atctagcaga gaaggcagag   1980

tgcttattca ctttggaagc gcactcgcag gagcagaaga agagagtgtg ctggtgcctg   2040

tcggagaaca tcgccaagca gcaacagctg gcagcatcac ccccggacag caagatgttt   2100

gagacggagg cagatgagaa gagggagatg gccttggagg aagggaaggg gcctggtgcc   2160

gaggattccc cacccagcaa ggagccctct cctggccagg agcttcctcc aggacaagac   2220

cttccaccca acaaggactc cccttctggg caggaacccg ctcccagcca agaaccactg   2280

tccagcaaag actcagctac ctctgaagga tcccctccag gcccagatgc tccgcccagc   2340

aaggatgtgc caccatgcca ggaaccccct ccagcccaag acctctcacc ctgccaggac   2400

ctacctgctg gtcaagaacc cctgcctcac caggaccctc tactcaccaa agacctccct   2460

gccatccagg aatcccccac ccgggacctt ccaccctgtc aagatctgcc tcctagccag   2520

gtctccctgc cagccaaggc ccttactgag gacaccatga gctccgggga cctactagca   2580

gctactgggg acccacctgc ggcccccagg ccagccttcg tgatccctga ggtccggctg   2640

gatagcacct acagccagaa ggcaggggca gagcagggct gctcgggaga tgaggaggat   2700

gcagaagagg ccgaggaggt ggaggagggg gaggaagggg aggaggacga ggatgaggac   2760

accagcgatg acaactacgg agagcgcagt gaggccaagc gcagcagcat gatcgagacg   2820

ggccaggggg ctgagggtgg cctctcactg cgtgtgcaga actcgctgcg gcgccggacg   2880

cacagcgagg gcagcctgct gcaggagccc cgagggccct gctttgcctc cgacaccacc   2940

ttgcactgct cagacggtga gggcgccgcc tccacctggg gcatgccttc gcccagcacc   3000

ctcaagaaag agctgggccg caatggtggc tccatgcacc acctttccct cttcttcaca   3060

ggacacagga agatgagcgg ggctgacacc gttggggatg atgacgaagc ctcccggaag   3120

agaaagagca aaaacctagc caaggacatg aagaacaagc tggggatctt cagacggcgg   3180

aatgagtccc ctggagcccc tcccgcgggc aaggcagaca aaatgatgaa gtcattcaag   3240

cccacctcag aggaagccct caagtggggc gagtccttgg agaagctgct ggttcacaaa   3300

tacgggttag cagtgttcca agccttcctt cgcactgagt tcagtgagga gaatctggag   3360

ttctggttgg cttgtgagga cttcaagaag gtcaagtcac agtccaagat ggcatccaag   3420

gccaagaaga tctttgctga atacatcgcg atccaggcat gcaaggaggt caacctggac   3480

tcctacacgc gggagcacac caaggacaac ctgcagagcg tcacgcgggg ctgcttcgac   3540

ctggcacaga agcgcatctt cgggctcatg gaaaaggact cgtaccctcg ctttctccgt   3600

tctgacctct acctggacct tattaaccag aagaagatga gtcccccgct ttaggggcca   3660

ctggagtcga gctcagcgtt cacaccaggc gggctgggtc ccctgcccac ctgcctccct   3720

gccccctgtg acggaggggg caagcaagcc cccagaggct gtgtctctgg acagacggat   3780

agacatacgg aagcgaggcc tggaccaaga gaggcccagg ctactggagg agtagaagga   3840

tgggccccgt ggggtcccca ctgccccggt acgagggggc ccaagaccct ggcaggtcag   3900

gggccctggc caagccagat ctggagctgc tgctccctgc tgcggagacc gcggaggctt   3960

cgcgttgacc aagttcctta aagaactggc tgatggggca ggaggtccag gcctgggctc   4020

tcgggccctc ctagagggcc attggagctt gcagctcaga cccccacttt gagttttatt   4080

tatttaaata gtagttggat gcttggcacg tcgtcctgta ataggaaacc cttgcctcat   4140

cagttttcct gatttacaag tgcaatattt tagccaatgc cttgggagaa gctgccatgc   4200

aaaggtggac accattctcc agcttcaggg gatatgctcg tcccgggcac cggtggcagg   4260

cagctggcct tctggactaa ggcagcctgg ggggacactg cagtctggct acacacagag   4320

atctggcacc ccctgggtgg agtgtccctc gggggctttg ggaaagcatg gcaccctcag   4380

accacacagt agccaagttc tggagcaaat aaaaggcctg tgttatttct tgttcttgac   4440

cctt                                                                4444


<210>  6249
<211>  1094
<212>  PRT
<213>  Homo sapiens

<400>  6249

Met Glu Trp Leu Ser Pro Asp Ile Ala Leu Pro Arg Arg Asp Glu Trp 
1               5                   10                  15


Thr Gln Thr Ser Pro Ala Arg Lys Arg Ile Thr His Ala Lys Val Gln 
            20                  25                  30


Gly Ala Gly Gln Leu Arg Leu Ser Ile Asp Ala Gln Asp Arg Val Leu 
        35                  40                  45


Leu Leu His Ile Ile Glu Gly Lys Gly Leu Ile Ser Lys Gln Pro Gly 
    50                  55                  60


Thr Cys Asp Pro Tyr Val Lys Ile Ser Leu Ile Pro Glu Asp Ser Arg 
65                  70                  75                  80


Leu Arg His Gln Lys Thr Gln Thr Val Pro Asp Cys Arg Asp Pro Ala 
                85                  90                  95


Phe His Glu His Phe Phe Phe Pro Val Gln Glu Glu Asp Asp Gln Lys 
            100                 105                 110


Arg Leu Leu Val Thr Val Trp Asn Arg Ala Ser Gln Ser Arg Gln Ser 
        115                 120                 125


Gly Leu Ile Gly Cys Met Ser Phe Gly Val Lys Ser Leu Leu Thr Pro 
    130                 135                 140


Asp Lys Glu Ile Ser Gly Trp Tyr Tyr Leu Leu Gly Glu His Leu Gly 
145                 150                 155                 160


Arg Thr Lys His Leu Lys Val Ala Arg Arg Arg Leu Arg Pro Leu Arg 
                165                 170                 175


Asp Pro Leu Leu Arg Met Pro Gly Gly Gly Asp Thr Glu Asn Gly Lys 
            180                 185                 190


Lys Leu Lys Ile Thr Ile Pro Arg Gly Lys Asp Gly Phe Gly Phe Thr 
        195                 200                 205


Ile Cys Cys Asp Ser Pro Val Arg Val Gln Ala Val Asp Ser Gly Gly 
    210                 215                 220


Pro Ala Glu Arg Ala Gly Leu Gln Gln Leu Asp Thr Val Leu Gln Leu 
225                 230                 235                 240


Asn Glu Arg Pro Val Glu His Trp Lys Cys Val Glu Leu Ala His Glu 
                245                 250                 255


Ile Arg Ser Cys Pro Ser Glu Ile Ile Leu Leu Val Trp Arg Met Val 
            260                 265                 270


Pro Gln Val Lys Pro Gly Pro Asp Gly Gly Val Leu Arg Arg Ala Ser 
        275                 280                 285


Cys Lys Ser Thr His Asp Leu Gln Ser Pro Pro Asn Lys Arg Glu Lys 
    290                 295                 300


Asn Cys Thr His Gly Val Gln Ala Arg Pro Glu Gln Arg His Ser Cys 
305                 310                 315                 320


His Leu Val Cys Asp Ser Ser Asp Gly Leu Leu Leu Gly Gly Trp Glu 
                325                 330                 335


Arg Tyr Thr Glu Val Ala Lys Arg Gly Gly Gln His Thr Leu Pro Ala 
            340                 345                 350


Leu Ser Arg Ala Thr Ala Pro Thr Asp Pro Asn Tyr Ile Ile Leu Ala 
        355                 360                 365


Pro Leu Asn Pro Gly Ser Gln Leu Leu Arg Pro Val Tyr Gln Glu Asp 
    370                 375                 380


Thr Ile Pro Glu Glu Ser Gly Ser Pro Ser Lys Gly Lys Ser Tyr Thr 
385                 390                 395                 400


Gly Leu Gly Lys Lys Ser Arg Leu Met Lys Thr Val Gln Thr Met Lys 
                405                 410                 415


Gly His Gly Asn Tyr Gln Asn Cys Pro Val Val Arg Pro His Ala Thr 
            420                 425                 430


His Ser Ser Tyr Gly Thr Tyr Val Thr Leu Ala Pro Lys Val Leu Val 
        435                 440                 445


Phe Pro Val Phe Val Gln Pro Leu Asp Leu Cys Asn Pro Ala Arg Thr 
    450                 455                 460


Leu Leu Leu Ser Glu Glu Leu Leu Leu Tyr Glu Gly Arg Asn Lys Ala 
465                 470                 475                 480


Ala Glu Val Thr Leu Phe Ala Tyr Ser Asp Leu Leu Leu Phe Thr Lys 
                485                 490                 495


Glu Asp Glu Pro Gly Arg Cys Asp Val Leu Arg Asn Pro Leu Tyr Leu 
            500                 505                 510


Gln Ser Val Lys Leu Gln Glu Gly Ser Ser Glu Asp Leu Lys Phe Cys 
        515                 520                 525


Val Leu Tyr Leu Ala Glu Lys Ala Glu Cys Leu Phe Thr Leu Glu Ala 
    530                 535                 540


His Ser Gln Glu Gln Lys Lys Arg Val Cys Trp Cys Leu Ser Glu Asn 
545                 550                 555                 560


Ile Ala Lys Gln Gln Gln Leu Ala Ala Ser Pro Pro Asp Ser Lys Met 
                565                 570                 575


Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu Gly 
            580                 585                 590


Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser Pro 
        595                 600                 605


Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp Ser 
    610                 615                 620


Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser Lys 
625                 630                 635                 640


Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro Pro 
                645                 650                 655


Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp Leu 
            660                 665                 670


Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His Gln 
        675                 680                 685


Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro Thr 
    690                 695                 700


Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser Leu 
705                 710                 715                 720


Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu Leu 
                725                 730                 735


Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val Ile 
            740                 745                 750


Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala Glu 
        755                 760                 765


Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu Val 
    770                 775                 780


Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser Asp 
785                 790                 795                 800


Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile Glu 
                805                 810                 815


Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn Ser 
            820                 825                 830


Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro Arg 
        835                 840                 845


Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly Glu 
    850                 855                 860


Gly Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr Leu Lys Lys 
865                 870                 875                 880


Glu Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser Leu Phe Phe 
                885                 890                 895


Thr Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly Asp Asp Asp 
            900                 905                 910


Glu Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Ala Lys Asp Met Lys 
        915                 920                 925


Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly Ala Pro 
    930                 935                 940


Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro Thr Ser 
945                 950                 955                 960


Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu Val His 
                965                 970                 975


Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu Phe Ser 
            980                 985                 990


Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys Lys Val 
        995                 1000                1005


Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe Ala Glu 
    1010                1015                1020


Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr Thr 
1025                1030                1035                1040


Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly Cys Phe 
                1045                1050                1055


Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp Ser Tyr 
            1060                1065                1070


Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln Lys 
        1075                1080                1085


Lys Met Ser Pro Pro Leu 
    1090


<210>  6250
<211>  4596
<212>  DNA
<213>  Homo sapiens

<400>  6250
aactttggct cagcctgtct tcatccactg tatcctgaca cctctcctac tccttctctt     60

taatgtacag ctgagactgg gataccctta gactgaaagg aaggacacgg ctatgtagaa    120

aagaattgac tgaaggggag gagtactcgt gaaccccttg cttcagcctc ccaatgttct    180

gagagaggag gagccaggcg cagtggctca tgcctgtaat cccagcactt tgggaggttg    240

agatgggcag atcgcaaggt caggagatcg agaccatcct ggctaacagg tcacattcag    300

acagcacacc tttgcccaat tttctttctg gatctcaccg tcctgagtgt tgtacctgca    360

ggttgctcac agcctctgga gcccaagata gtctcccctt tgggaggagg ctctacagtg    420

gtccctggcg aagttgtgaa gaggtctgcc acgtctctgt gctcagtgtc ctctctacat    480

cctgtggctt gagcctgagc ttgcccatat tccctggctg gatggagtgg ctaagccctg    540

atatcgctct gcccagaaga gatgagtgga ctcaaacttc tccagccagg aagaggatca    600

cgcatgccaa agtccagggt gcaggtcagc tgaggctgtc cattgatgcc caggaccggg    660

ttctgctgct tcacattata gaaggtaaag gcctgatcag caaacagcct ggcacctgtg    720

atccgtatgt gaagatttct ttgatccctg aagatagtag actacgccac cagaagacgc    780

agaccgttcc agactgcaga gacccggctt tccacgagca cttcttcttt cctgtccaag    840

aggaggatga tcagaagcgt ctcttggtta ctgtgtggaa cagggccagc cagtccagac    900

agagtggact cattggctgc atgagctttg gggtgaagtc tctcctgact ccagacaagg    960

agatcagtgg ttggtactac ctcctagggg agcacctggg ccggaccaag cacttgaagg   1020

tggccaggcg gcgactgcgg ccgctgagag acccgctgct gagaatgcca ggaggtgggg   1080

acactgagaa tgggaagaaa ctaaagatca ccatcccgag gggaaaggac ggctttggct   1140

tcaccatctg ctgcgactct ccagttcgag tccaggccgt ggattccggg ggtccggcgg   1200

aacgggcagg gctgcagcag ctggacacgg tgctgcagct gaatgagagg cctgtggagc   1260

actggaaatg tgtggagctg gcccacgaga tccggagctg ccccagtgag atcatcctac   1320

tcgtgtggcg catggtcccc caggtcaagc caggaccaga tggcggggtc ctgcggcggg   1380

cctcctgcaa gtcgacacat gacctccagt caccccccaa caaacgggag aagaactgca   1440

cccatggggt ccaggcacgg cctgagcagc gccacagctg ccacctggta tgtgacagct   1500

ctgatgggct gctgctcggc ggctgggagc gctacaccga ggtggccaag cgcgggggcc   1560

agcacaccct gcctgcactg tcccgtgcca ctgcccccac cgaccccaac tacatcatcc   1620

tggccccgct gaatcctggg agccagctgc tccggcctgt gtaccaggag gataccatcc   1680

ccgaagaatc agggagtccc agtaaaggga agtcctacac aggcctgggg aagaagtccc   1740

ggctgatgaa gacagtgcag accatgaagg gccacgggaa ctaccaaaac tgcccggttg   1800

tgaggccgca tgccacgcac tcaagctatg gcacctacgt caccctggcc cccaaagtcc   1860

tggtgttccc tgtctttgtt cagcctctag atctctgtaa tcctgcccgg accctcctgc   1920

tgtcagagga gctgctgctg tatgaaggga ggaacaaggc tgccgaggtg acactgtttg   1980

cctattcgga cctgctgctc ttcaccaagg aggacgagcc tggccgctgc gacgtcctga   2040

ggaaccccct ctacctccag agtgtgaagc tgcaggaagg ttcttcagaa gacctgaaat   2100

tctgcgtgct ctatctagca gagaaggcag agtgcttatt cactttggaa gcgcactcgc   2160

aggagcagaa gaagagagtg tgctggtgcc tgtcggagaa catcgccaag cagcaacagc   2220

tggcagcatc acccccggac agcaagatgt ttgagacgga ggcagatgag aagagggaga   2280

tggccttgga ggaagggaag gggcctggtg ccgaggattc cccacccagc aaggagccct   2340

ctcctggcca ggagcttcct ccaggacaag accttccacc caacaaggac tccccttctg   2400

ggcaggaacc cgctcccagc caagaaccac tgtccagcaa agactcagct acctctgaag   2460

gatcccctcc aggcccagat gctccgccca gcaaggatgt gccaccatgc caggaacccc   2520

ctccagccca agacctctca ccctgccagg acctacctgc tggtcaagaa cccctgcctc   2580

accaggaccc tctactcacc aaagacctcc ctgccatcca ggaatccccc acccgggacc   2640

ttccaccctg tcaagatctg cctcctagcc aggtctccct gccagccaag gcccttactg   2700

aggacaccat gagctccggg gacctactag cagctactgg ggacccacct gcggccccca   2760

ggccagcctt cgtgatccct gaggtccggc tggatagcac ctacagccag aaggcagggg   2820

cagagcaggg ctgctcggga gatgaggagg atgcagaaga ggccgaggag gtggaggagg   2880

gggaggaagg ggaggaggac gaggatgagg acaccagcga tgacaactac ggagagcgca   2940

gtgaggccaa gcgcagcagc atgatcgaga cgggccaggg ggctgagggt ggcctctcac   3000

tgcgtgtgca gaactcgctg cggcgccgga cgcacagcga gggcagcctg ctgcaggagc   3060

cccgagggcc ctgctttgcc tccgacacca ccttgcactg ctcagacggt gagggcgccg   3120

cctccacctg gggcatgcct tcgcccagca ccctcaagaa agagctgggc cgcaatggtg   3180

gctccatgca ccacctttcc ctcttcttca caggacacag gaagatgagc ggggctgaca   3240

ccgttgggga tgatgacgaa gcctcccgga agagaaagag caaaaaccta gccaaggaca   3300

tgaagaacaa gctggggatc ttcagacggc ggaatgagtc ccctggagcc cctcccgcgg   3360

gcaaggcaga caaaatgatg aagtcattca agcccacctc agaggaagcc ctcaagtggg   3420

gcgagtcctt ggagaagctg ctggttcaca aatacgggtt agcagtgttc caagccttcc   3480

ttcgcactga gttcagtgag gagaatctgg agttctggtt ggcttgtgag gacttcaaga   3540

aggtcaagtc acagtccaag atggcatcca aggccaagaa gatctttgct gaatacatcg   3600

cgatccaggc atgcaaggag gtcaacctgg actcctacac gcgggagcac accaaggaca   3660

acctgcagag cgtcacgcgg ggctgcttcg acctggcaca gaagcgcatc ttcgggctca   3720

tggaaaagga ctcgtaccct cgctttctcc gttctgacct ctacctggac cttattaacc   3780

agaagaagat gagtcccccg ctttaggggc cactggagtc gagctcagcg ttcacaccag   3840

gcgggctggg tcccctgccc acctgcctcc ctgccccctg tgacggaggg ggcaagcaag   3900

cccccagagg ctgtgtctct ggacagacgg atagacatac ggaagcgagg cctggaccaa   3960

gagaggccca ggctactgga ggagtagaag gatgggcccc gtggggtccc cactgccccg   4020

gtacgagggg gcccaagacc ctggcaggtc aggggccctg gccaagccag atctggagct   4080

gctgctccct gctgcggaga ccgcggaggc ttcgcgttga ccaagttcct taaagaactg   4140

gctgatgggg caggaggtcc aggcctgggc tctcgggccc tcctagaggg ccattggagc   4200

ttgcagctca gacccccact ttgagtttta tttatttaaa tagtagttgg atgcttggca   4260

cgtcgtcctg taataggaaa cccttgcctc atcagttttc ctgatttaca agtgcaatat   4320

tttagccaat gccttgggag aagctgccat gcaaaggtgg acaccattct ccagcttcag   4380

gggatatgct cgtcccgggc accggtggca ggcagctggc cttctggact aaggcagcct   4440

ggggggacac tgcagtctgg ctacacacag agatctggca ccccctgggt ggagtgtccc   4500

tcgggggctt tgggaaagca tggcaccctc agaccacaca gtagccaagt tctggagcaa   4560

ataaaaggcc tgtgttattt cttgttcttg accctt                             4596


<210>  6251
<211>  1198
<212>  PRT
<213>  Homo sapiens

<400>  6251

Met Pro Val Ile Pro Ala Leu Trp Glu Val Glu Met Gly Arg Ser Gln 
1               5                   10                  15


Gly Gln Glu Ile Glu Thr Ile Leu Ala Asn Arg Ser His Ser Asp Ser 
            20                  25                  30


Thr Pro Leu Pro Asn Phe Leu Ser Gly Ser His Arg Pro Glu Cys Cys 
        35                  40                  45


Thr Cys Arg Leu Leu Thr Ala Ser Gly Ala Gln Asp Ser Leu Pro Phe 
    50                  55                  60


Gly Arg Arg Leu Tyr Ser Gly Pro Trp Arg Ser Cys Glu Glu Val Cys 
65                  70                  75                  80


His Val Ser Val Leu Ser Val Leu Ser Thr Ser Cys Gly Leu Ser Leu 
                85                  90                  95


Ser Leu Pro Ile Phe Pro Gly Trp Met Glu Trp Leu Ser Pro Asp Ile 
            100                 105                 110


Ala Leu Pro Arg Arg Asp Glu Trp Thr Gln Thr Ser Pro Ala Arg Lys 
        115                 120                 125


Arg Ile Thr His Ala Lys Val Gln Gly Ala Gly Gln Leu Arg Leu Ser 
    130                 135                 140


Ile Asp Ala Gln Asp Arg Val Leu Leu Leu His Ile Ile Glu Gly Lys 
145                 150                 155                 160


Gly Leu Ile Ser Lys Gln Pro Gly Thr Cys Asp Pro Tyr Val Lys Ile 
                165                 170                 175


Ser Leu Ile Pro Glu Asp Ser Arg Leu Arg His Gln Lys Thr Gln Thr 
            180                 185                 190


Val Pro Asp Cys Arg Asp Pro Ala Phe His Glu His Phe Phe Phe Pro 
        195                 200                 205


Val Gln Glu Glu Asp Asp Gln Lys Arg Leu Leu Val Thr Val Trp Asn 
    210                 215                 220


Arg Ala Ser Gln Ser Arg Gln Ser Gly Leu Ile Gly Cys Met Ser Phe 
225                 230                 235                 240


Gly Val Lys Ser Leu Leu Thr Pro Asp Lys Glu Ile Ser Gly Trp Tyr 
                245                 250                 255


Tyr Leu Leu Gly Glu His Leu Gly Arg Thr Lys His Leu Lys Val Ala 
            260                 265                 270


Arg Arg Arg Leu Arg Pro Leu Arg Asp Pro Leu Leu Arg Met Pro Gly 
        275                 280                 285


Gly Gly Asp Thr Glu Asn Gly Lys Lys Leu Lys Ile Thr Ile Pro Arg 
    290                 295                 300


Gly Lys Asp Gly Phe Gly Phe Thr Ile Cys Cys Asp Ser Pro Val Arg 
305                 310                 315                 320


Val Gln Ala Val Asp Ser Gly Gly Pro Ala Glu Arg Ala Gly Leu Gln 
                325                 330                 335


Gln Leu Asp Thr Val Leu Gln Leu Asn Glu Arg Pro Val Glu His Trp 
            340                 345                 350


Lys Cys Val Glu Leu Ala His Glu Ile Arg Ser Cys Pro Ser Glu Ile 
        355                 360                 365


Ile Leu Leu Val Trp Arg Met Val Pro Gln Val Lys Pro Gly Pro Asp 
    370                 375                 380


Gly Gly Val Leu Arg Arg Ala Ser Cys Lys Ser Thr His Asp Leu Gln 
385                 390                 395                 400


Ser Pro Pro Asn Lys Arg Glu Lys Asn Cys Thr His Gly Val Gln Ala 
                405                 410                 415


Arg Pro Glu Gln Arg His Ser Cys His Leu Val Cys Asp Ser Ser Asp 
            420                 425                 430


Gly Leu Leu Leu Gly Gly Trp Glu Arg Tyr Thr Glu Val Ala Lys Arg 
        435                 440                 445


Gly Gly Gln His Thr Leu Pro Ala Leu Ser Arg Ala Thr Ala Pro Thr 
    450                 455                 460


Asp Pro Asn Tyr Ile Ile Leu Ala Pro Leu Asn Pro Gly Ser Gln Leu 
465                 470                 475                 480


Leu Arg Pro Val Tyr Gln Glu Asp Thr Ile Pro Glu Glu Ser Gly Ser 
                485                 490                 495


Pro Ser Lys Gly Lys Ser Tyr Thr Gly Leu Gly Lys Lys Ser Arg Leu 
            500                 505                 510


Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln Asn Cys 
        515                 520                 525


Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr Tyr Val 
    530                 535                 540


Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln Pro Leu 
545                 550                 555                 560


Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu 
                565                 570                 575


Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr 
            580                 585                 590


Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp 
        595                 600                 605


Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly 
    610                 615                 620


Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala 
625                 630                 635                 640


Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys Lys Arg 
                645                 650                 655


Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala 
            660                 665                 670


Ala Ser Pro Pro Asp Ser Lys Met Phe Glu Thr Glu Ala Asp Glu Lys 
        675                 680                 685


Arg Glu Met Ala Leu Glu Glu Gly Lys Gly Pro Gly Ala Glu Asp Ser 
    690                 695                 700


Pro Pro Ser Lys Glu Pro Ser Pro Gly Gln Glu Leu Pro Pro Gly Gln 
705                 710                 715                 720


Asp Leu Pro Pro Asn Lys Asp Ser Pro Ser Gly Gln Glu Pro Ala Pro 
                725                 730                 735


Ser Gln Glu Pro Leu Ser Ser Lys Asp Ser Ala Thr Ser Glu Gly Ser 
            740                 745                 750


Pro Pro Gly Pro Asp Ala Pro Pro Ser Lys Asp Val Pro Pro Cys Gln 
        755                 760                 765


Glu Pro Pro Pro Ala Gln Asp Leu Ser Pro Cys Gln Asp Leu Pro Ala 
    770                 775                 780


Gly Gln Glu Pro Leu Pro His Gln Asp Pro Leu Leu Thr Lys Asp Leu 
785                 790                 795                 800


Pro Ala Ile Gln Glu Ser Pro Thr Arg Asp Leu Pro Pro Cys Gln Asp 
                805                 810                 815


Leu Pro Pro Ser Gln Val Ser Leu Pro Ala Lys Ala Leu Thr Glu Asp 
            820                 825                 830


Thr Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala 
        835                 840                 845


Ala Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr 
    850                 855                 860


Tyr Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu 
865                 870                 875                 880


Asp Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu 
                885                 890                 895


Asp Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu 
            900                 905                 910


Ala Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly 
        915                 920                 925


Leu Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu 
    930                 935                 940


Gly Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr 
945                 950                 955                 960


Thr Leu His Cys Ser Asp Gly Glu Gly Ala Ala Ser Thr Trp Gly Met 
                965                 970                 975


Pro Ser Pro Ser Thr Leu Lys Lys Glu Leu Gly Arg Asn Gly Gly Ser 
            980                 985                 990


Met His His Leu Ser Leu Phe Phe Thr Gly His Arg Lys Met Ser Gly 
        995                 1000                1005


Ala Asp Thr Val Gly Asp Asp Asp Glu Ala Ser Arg Lys Arg Lys Ser 
    1010                1015                1020


Lys Asn Leu Ala Lys Asp Met Lys Asn Lys Leu Gly Ile Phe Arg Arg 
1025                1030                1035                1040


Arg Asn Glu Ser Pro Gly Ala Pro Pro Ala Gly Lys Ala Asp Lys Met 
                1045                1050                1055


Met Lys Ser Phe Lys Pro Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu 
            1060                1065                1070


Ser Leu Glu Lys Leu Leu Val His Lys Tyr Gly Leu Ala Val Phe Gln 
        1075                1080                1085


Ala Phe Leu Arg Thr Glu Phe Ser Glu Glu Asn Leu Glu Phe Trp Leu 
    1090                1095                1100


Ala Cys Glu Asp Phe Lys Lys Val Lys Ser Gln Ser Lys Met Ala Ser 
1105                1110                1115                1120


Lys Ala Lys Lys Ile Phe Ala Glu Tyr Ile Ala Ile Gln Ala Cys Lys 
                1125                1130                1135


Glu Val Asn Leu Asp Ser Tyr Thr Arg Glu His Thr Lys Asp Asn Leu 
            1140                1145                1150


Gln Ser Val Thr Arg Gly Cys Phe Asp Leu Ala Gln Lys Arg Ile Phe 
        1155                1160                1165


Gly Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Arg Ser Asp Leu 
    1170                1175                1180


Tyr Leu Asp Leu Ile Asn Gln Lys Lys Met Ser Pro Pro Leu 
1185                1190                1195


<210>  6252
<211>  4427
<212>  DNA
<213>  Homo sapiens

<400>  6252
cccaccatct gggcctaagg aagcagaagc gcagtggctc atgcctgtaa tcccagcact     60

ttgggaggtt gagatgggca gatcgcaagg tcaggagatc gagaccatcc tggctaacag    120

gtcacattca gacagcacac ctttgcccaa ttttctttct ggatctcacc gtcctgagtg    180

ttgtacctgc aggttgctca cagcctctgg agcccaagat agtctcccct ttgggaggag    240

gctctacagt ggtccctggc gaagttgtga agaggtctgc cacgtctctg tgctcagtgt    300

cctctctaca tcctgtggct tgagcctgag cttgcccata ttccctggct ggatggagtg    360

gctaagccct gatatcgctc tgcccagaag agatgagtgg actcaaactt ctccagccag    420

gaagaggatc acgcatgcca aagtccaggg tgcaggtcag ctgaggctgt ccattgatgc    480

ccaggaccgg gttctgctgc ttcacattat agaaggtaaa ggcctgatca gcaaacagcc    540

tggcacctgt gatccgtatg tgaagatttc tttgatccct gaagatagta gactacgcca    600

ccagaagacg cagaccgttc cagactgcag agacccggct ttccacgagc acttcttctt    660

tcctgtccaa gaggaggatg atcagaagcg tctcttggtt actgtgtgga acagggccag    720

ccagtccaga cagagtggac tcattggctg catgagcttt ggggtgaagt ctctcctgac    780

tccagacaag gagatcagtg gttggtacta cctcctaggg gagcacctgg gccggaccaa    840

gcacttgaag gtggccaggc ggcgactgcg gccgctgaga gacccgctgc tgagaatgcc    900

aggaggtggg gacactgaga atgggaagaa actaaagatc accatcccga ggggaaagga    960

cggctttggc ttcaccatct gctgcgactc tccagttcga gtccaggccg tggattccgg   1020

gggtccggcg gaacgggcag ggctgcagca gctggacacg gtgctgcagc tgaatgagag   1080

gcctgtggag cactggaaat gtgtggagct ggcccacgag atccggagct gccccagtga   1140

gatcatccta ctcgtgtggc gcatggtccc ccaggtcaag ccaggaccag atggcggggt   1200

cctgcggcgg gcctcctgca agtcgacaca tgacctccag tcacccccca acaaacggga   1260

gaagaactgc acccatgggg tccaggcacg gcctgagcag cgccacagct gccacctggt   1320

atgtgacagc tctgatgggc tgctgctcgg cggctgggag cgctacaccg aggtggccaa   1380

gcgcgggggc cagcacaccc tgcctgcact gtcccgtgcc actgccccca ccgaccccaa   1440

ctacatcatc ctggccccgc tgaatcctgg gagccagctg ctccggcctg tgtaccagga   1500

ggataccatc cccgaagaat cagggagtcc cagtaaaggg aagtcctaca caggcctggg   1560

gaagaagtcc cggctgatga agacagtgca gaccatgaag ggccacggga actaccaaaa   1620

ctgcccggtt gtgaggccgc atgccacgca ctcaagctat ggcacctacg tcaccctggc   1680

ccccaaagtc ctggtgttcc ctgtctttgt tcagcctcta gatctctgta atcctgcccg   1740

gaccctcctg ctgtcagagg agctgctgct gtatgaaggg aggaacaagg ctgccgaggt   1800

gacactgttt gcctattcgg acctgctgct cttcaccaag gaggacgagc ctggccgctg   1860

cgacgtcctg aggaaccccc tctacctcca gagtgtgaag ctgcaggaag gttcttcaga   1920

agacctgaaa ttctgcgtgc tctatctagc agagaaggca gagtgcttat tcactttgga   1980

agcgcactcg caggagcaga agaagagagt gtgctggtgc ctgtcggaga acatcgccaa   2040

gcagcaacag ctggcagcat cacccccgga cagcaagatg tttgagacgg aggcagatga   2100

gaagagggag atggccttgg aggaagggaa ggggcctggt gccgaggatt ccccacccag   2160

caaggagccc tctcctggcc aggagcttcc tccaggacaa gaccttccac ccaacaagga   2220

ctccccttct gggcaggaac ccgctcccag ccaagaacca ctgtccagca aagactcagc   2280

tacctctgaa ggatcccctc caggcccaga tgctccgccc agcaaggatg tgccaccatg   2340

ccaggaaccc cctccagccc aagacctctc accctgccag gacctacctg ctggtcaaga   2400

acccctgcct caccaggacc ctctactcac caaagacctc cctgccatcc aggaatcccc   2460

cacccgggac cttccaccct gtcaagatct gcctcctagc caggtctccc tgccagccaa   2520

ggcccttact gaggacacca tgagctccgg ggacctacta gcagctactg gggacccacc   2580

tgcggccccc aggccagcct tcgtgatccc tgaggtccgg ctggatagca cctacagcca   2640

gaaggcaggg gcagagcagg gctgctcggg agatgaggag gatgcagaag aggccgagga   2700

ggtggaggag ggggaggaag gggaggagga cgaggatgag gacaccagcg atgacaacta   2760

cggagagcgc agtgaggcca agcgcagcag catgatcgag acgggccagg gggctgaggg   2820

tggcctctca ctgcgtgtgc agaactcgct gcggcgccgg acgcacagcg agggcagcct   2880

gctgcaggag ccccgagggc cctgctttgc ctccgacacc accttgcact gctcagacgg   2940

tgagggcgcc gcctccacct ggggcatgcc ttcgcccagc accctcaaga aagagctggg   3000

ccgcaatggt ggctccatgc accacctttc cctcttcttc acaggacaca ggaagatgag   3060

cggggctgac accgttgggg atgatgacga agcctcccgg aagagaaaga gcaaaaacct   3120

agccaaggac atgaagaaca agctggggat cttcagacgg cggaatgagt cccctggagc   3180

ccctcccgcg ggcaaggcag acaaaatgat gaagtcattc aagcccacct cagaggaagc   3240

cctcaagtgg ggcgagtcct tggagaagct gctggttcac aaatacgggt tagcagtgtt   3300

ccaagccttc cttcgcactg agttcagtga ggagaatctg gagttctggt tggcttgtga   3360

ggacttcaag aaggtcaagt cacagtccaa gatggcatcc aaggccaaga agatctttgc   3420

tgaatacatc gcgatccagg catgcaagga ggtcaacctg gactcctaca cgcgggagca   3480

caccaaggac aacctgcaga gcgtcacgcg gggctgcttc gacctggcac agaagcgcat   3540

cttcgggctc atggaaaagg actcgtaccc tcgctttctc cgttctgacc tctacctgga   3600

ccttattaac cagaagaaga tgagtccccc gctttagggg ccactggagt cgagctcagc   3660

gttcacacca ggcgggctgg gtcccctgcc cacctgcctc cctgccccct gtgacggagg   3720

gggcaagcaa gcccccagag gctgtgtctc tggacagacg gatagacata cggaagcgag   3780

gcctggacca agagaggccc aggctactgg aggagtagaa ggatgggccc cgtggggtcc   3840

ccactgcccc ggtacgaggg ggcccaagac cctggcaggt caggggccct ggccaagcca   3900

gatctggagc tgctgctccc tgctgcggag accgcggagg cttcgcgttg accaagttcc   3960

ttaaagaact ggctgatggg gcaggaggtc caggcctggg ctctcgggcc ctcctagagg   4020

gccattggag cttgcagctc agacccccac tttgagtttt atttatttaa atagtagttg   4080

gatgcttggc acgtcgtcct gtaataggaa acccttgcct catcagtttt cctgatttac   4140

aagtgcaata ttttagccaa tgccttggga gaagctgcca tgcaaaggtg gacaccattc   4200

tccagcttca ggggatatgc tcgtcccggg caccggtggc aggcagctgg ccttctggac   4260

taaggcagcc tggggggaca ctgcagtctg gctacacaca gagatctggc accccctggg   4320

tggagtgtcc ctcgggggct ttgggaaagc atggcaccct cagaccacac agtagccaag   4380

ttctggagca aataaaaggc ctgtgttatt tcttgttctt gaccctt                 4427


<210>  6253
<211>  1198
<212>  PRT
<213>  Homo sapiens

<400>  6253

Met Pro Val Ile Pro Ala Leu Trp Glu Val Glu Met Gly Arg Ser Gln 
1               5                   10                  15


Gly Gln Glu Ile Glu Thr Ile Leu Ala Asn Arg Ser His Ser Asp Ser 
            20                  25                  30


Thr Pro Leu Pro Asn Phe Leu Ser Gly Ser His Arg Pro Glu Cys Cys 
        35                  40                  45


Thr Cys Arg Leu Leu Thr Ala Ser Gly Ala Gln Asp Ser Leu Pro Phe 
    50                  55                  60


Gly Arg Arg Leu Tyr Ser Gly Pro Trp Arg Ser Cys Glu Glu Val Cys 
65                  70                  75                  80


His Val Ser Val Leu Ser Val Leu Ser Thr Ser Cys Gly Leu Ser Leu 
                85                  90                  95


Ser Leu Pro Ile Phe Pro Gly Trp Met Glu Trp Leu Ser Pro Asp Ile 
            100                 105                 110


Ala Leu Pro Arg Arg Asp Glu Trp Thr Gln Thr Ser Pro Ala Arg Lys 
        115                 120                 125


Arg Ile Thr His Ala Lys Val Gln Gly Ala Gly Gln Leu Arg Leu Ser 
    130                 135                 140


Ile Asp Ala Gln Asp Arg Val Leu Leu Leu His Ile Ile Glu Gly Lys 
145                 150                 155                 160


Gly Leu Ile Ser Lys Gln Pro Gly Thr Cys Asp Pro Tyr Val Lys Ile 
                165                 170                 175


Ser Leu Ile Pro Glu Asp Ser Arg Leu Arg His Gln Lys Thr Gln Thr 
            180                 185                 190


Val Pro Asp Cys Arg Asp Pro Ala Phe His Glu His Phe Phe Phe Pro 
        195                 200                 205


Val Gln Glu Glu Asp Asp Gln Lys Arg Leu Leu Val Thr Val Trp Asn 
    210                 215                 220


Arg Ala Ser Gln Ser Arg Gln Ser Gly Leu Ile Gly Cys Met Ser Phe 
225                 230                 235                 240


Gly Val Lys Ser Leu Leu Thr Pro Asp Lys Glu Ile Ser Gly Trp Tyr 
                245                 250                 255


Tyr Leu Leu Gly Glu His Leu Gly Arg Thr Lys His Leu Lys Val Ala 
            260                 265                 270


Arg Arg Arg Leu Arg Pro Leu Arg Asp Pro Leu Leu Arg Met Pro Gly 
        275                 280                 285


Gly Gly Asp Thr Glu Asn Gly Lys Lys Leu Lys Ile Thr Ile Pro Arg 
    290                 295                 300


Gly Lys Asp Gly Phe Gly Phe Thr Ile Cys Cys Asp Ser Pro Val Arg 
305                 310                 315                 320


Val Gln Ala Val Asp Ser Gly Gly Pro Ala Glu Arg Ala Gly Leu Gln 
                325                 330                 335


Gln Leu Asp Thr Val Leu Gln Leu Asn Glu Arg Pro Val Glu His Trp 
            340                 345                 350


Lys Cys Val Glu Leu Ala His Glu Ile Arg Ser Cys Pro Ser Glu Ile 
        355                 360                 365


Ile Leu Leu Val Trp Arg Met Val Pro Gln Val Lys Pro Gly Pro Asp 
    370                 375                 380


Gly Gly Val Leu Arg Arg Ala Ser Cys Lys Ser Thr His Asp Leu Gln 
385                 390                 395                 400


Ser Pro Pro Asn Lys Arg Glu Lys Asn Cys Thr His Gly Val Gln Ala 
                405                 410                 415


Arg Pro Glu Gln Arg His Ser Cys His Leu Val Cys Asp Ser Ser Asp 
            420                 425                 430


Gly Leu Leu Leu Gly Gly Trp Glu Arg Tyr Thr Glu Val Ala Lys Arg 
        435                 440                 445


Gly Gly Gln His Thr Leu Pro Ala Leu Ser Arg Ala Thr Ala Pro Thr 
    450                 455                 460


Asp Pro Asn Tyr Ile Ile Leu Ala Pro Leu Asn Pro Gly Ser Gln Leu 
465                 470                 475                 480


Leu Arg Pro Val Tyr Gln Glu Asp Thr Ile Pro Glu Glu Ser Gly Ser 
                485                 490                 495


Pro Ser Lys Gly Lys Ser Tyr Thr Gly Leu Gly Lys Lys Ser Arg Leu 
            500                 505                 510


Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln Asn Cys 
        515                 520                 525


Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr Tyr Val 
    530                 535                 540


Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln Pro Leu 
545                 550                 555                 560


Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu 
                565                 570                 575


Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr 
            580                 585                 590


Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp 
        595                 600                 605


Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly 
    610                 615                 620


Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala 
625                 630                 635                 640


Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys Lys Arg 
                645                 650                 655


Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala 
            660                 665                 670


Ala Ser Pro Pro Asp Ser Lys Met Phe Glu Thr Glu Ala Asp Glu Lys 
        675                 680                 685


Arg Glu Met Ala Leu Glu Glu Gly Lys Gly Pro Gly Ala Glu Asp Ser 
    690                 695                 700


Pro Pro Ser Lys Glu Pro Ser Pro Gly Gln Glu Leu Pro Pro Gly Gln 
705                 710                 715                 720


Asp Leu Pro Pro Asn Lys Asp Ser Pro Ser Gly Gln Glu Pro Ala Pro 
                725                 730                 735


Ser Gln Glu Pro Leu Ser Ser Lys Asp Ser Ala Thr Ser Glu Gly Ser 
            740                 745                 750


Pro Pro Gly Pro Asp Ala Pro Pro Ser Lys Asp Val Pro Pro Cys Gln 
        755                 760                 765


Glu Pro Pro Pro Ala Gln Asp Leu Ser Pro Cys Gln Asp Leu Pro Ala 
    770                 775                 780


Gly Gln Glu Pro Leu Pro His Gln Asp Pro Leu Leu Thr Lys Asp Leu 
785                 790                 795                 800


Pro Ala Ile Gln Glu Ser Pro Thr Arg Asp Leu Pro Pro Cys Gln Asp 
                805                 810                 815


Leu Pro Pro Ser Gln Val Ser Leu Pro Ala Lys Ala Leu Thr Glu Asp 
            820                 825                 830


Thr Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala 
        835                 840                 845


Ala Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr 
    850                 855                 860


Tyr Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu 
865                 870                 875                 880


Asp Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu 
                885                 890                 895


Asp Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu 
            900                 905                 910


Ala Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly 
        915                 920                 925


Leu Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu 
    930                 935                 940


Gly Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr 
945                 950                 955                 960


Thr Leu His Cys Ser Asp Gly Glu Gly Ala Ala Ser Thr Trp Gly Met 
                965                 970                 975


Pro Ser Pro Ser Thr Leu Lys Lys Glu Leu Gly Arg Asn Gly Gly Ser 
            980                 985                 990


Met His His Leu Ser Leu Phe Phe Thr Gly His Arg Lys Met Ser Gly 
        995                 1000                1005


Ala Asp Thr Val Gly Asp Asp Asp Glu Ala Ser Arg Lys Arg Lys Ser 
    1010                1015                1020


Lys Asn Leu Ala Lys Asp Met Lys Asn Lys Leu Gly Ile Phe Arg Arg 
1025                1030                1035                1040


Arg Asn Glu Ser Pro Gly Ala Pro Pro Ala Gly Lys Ala Asp Lys Met 
                1045                1050                1055


Met Lys Ser Phe Lys Pro Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu 
            1060                1065                1070


Ser Leu Glu Lys Leu Leu Val His Lys Tyr Gly Leu Ala Val Phe Gln 
        1075                1080                1085


Ala Phe Leu Arg Thr Glu Phe Ser Glu Glu Asn Leu Glu Phe Trp Leu 
    1090                1095                1100


Ala Cys Glu Asp Phe Lys Lys Val Lys Ser Gln Ser Lys Met Ala Ser 
1105                1110                1115                1120


Lys Ala Lys Lys Ile Phe Ala Glu Tyr Ile Ala Ile Gln Ala Cys Lys 
                1125                1130                1135


Glu Val Asn Leu Asp Ser Tyr Thr Arg Glu His Thr Lys Asp Asn Leu 
            1140                1145                1150


Gln Ser Val Thr Arg Gly Cys Phe Asp Leu Ala Gln Lys Arg Ile Phe 
        1155                1160                1165


Gly Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Arg Ser Asp Leu 
    1170                1175                1180


Tyr Leu Asp Leu Ile Asn Gln Lys Lys Met Ser Pro Pro Leu 
1185                1190                1195


<210>  6254
<211>  2640
<212>  DNA
<213>  Homo sapiens

<400>  6254
ttcaaacccg cgcgggccaa tcagggccgg gcgcgccctg gccgttccaa cgcttggggc     60

agccctacct cccgctcgcg ctcctcccgc cctggagact ccggttactg gggagcaaca    120

cagccgcctc gggttgcaga cgctcctgtc cgggtcgcag tgggacgcca tggagcgctc    180

cctgcaccgc gtctccctcg ggagccggcg tgcccacccg gacttgtcct tctacctcac    240

cacctttggt cagctgaggc tgtccattga tgcccaggac cgggttctgc tgcttcacat    300

tatagaaggt aaaggcctga tcagcaaaca gcctggcacc tgtgatccgt atgtgaagat    360

ttctttgatc cctgaagata gtagactacg ccaccagaag acgcagaccg ttccagactg    420

cagagacccg gctttccacg agcacttctt ctttcctgtc caagaggagg atgatcagaa    480

gcgtctcttg gttactgtgt ggaacagggc cagccagtcc agacagagtg gactcattgg    540

ctgcatgagc tttggggtga agtctctcct gactccagac aaggagatca gtggttggta    600

ctacctccta ggggagcacc tgggccggac caagcacttg aaggtggcca ggcggcgact    660

gcggccgctg agagacccgc tgctgagaat gccaggaggt ggggacactg agaatgggaa    720

gaaactaaag atcaccatcc cgaggggaaa ggacggcttt ggcttcacca tctgctgcga    780

ctctccagtt cgagtccagg ccgtggattc cgggggtccg gcggaacggg cagggctgca    840

gcagctggac acggtgctgc agctgaatga gaggcctgtg gagcactgga aatgtgtgga    900

gctggcccac gagatccgga gctgccccag tgagatcatc ctactcgtgt ggcgcatggt    960

cccccaggtc aagccaggac cagatggcgg ggtcctgcgg cgggcctcct gcaagtcgac   1020

acatgacctc cagtcacccc ccaacaaacg ggagaagaac tgcacccatg gggtccaggc   1080

acggcctgag cagcgccaca gctgccacct ggtatgtgac agctctgatg ggctgctgct   1140

cggcggctgg gagcgctaca ccgaggtggc caagcgcggg ggccagcaca ccctgcctgc   1200

actgtcccgt gccactgccc ccaccgaccc caactacatc atcctggccc cgctgaatcc   1260

tgggagccag ctgctccggc ctgtgtacca ggaggatacc atccccgaag aatcagggag   1320

tcccagtaaa gggaagtcct acacaggcct ggggaagaag tcccggctga tgaagacagt   1380

gcagaccatg aagggccacg ggaactacca aaactgcccg gttgtgaggc cgcatgccac   1440

gcactcaagc tatggcacct acgtcaccct ggcccccaaa gtcctggtgt tccctgtctt   1500

tgttcagcct ctagatctct gtaatcctgc ccggaccctc ctgctgtcag aggagctgct   1560

gctgtatgaa gggaggaaca aggctgccga ggtgacactg tttgcctatt cggacctgct   1620

gctcttcacc aaggaggacg agcctggccg ctgcgacgtc ctgaggaacc ccctctacct   1680

ccagagtgtg aagctgcagg aaggttcttc agaagacctg aaattctgcg tgctctatct   1740

agcagagaag gcagagtgct tattcacttt ggaagcgcac tcgcaggagc agaagaagag   1800

agtgtgctgg tgcctgtcgg agaacatcgc caagcagcaa cagctggcag catcaccccc   1860

ggacagcaag aaactccacc ctttcggctc tctccagcag gagatggggc cggtcaactc   1920

aaccaatgcc acccaggata gaagctttac ctcaccagga cagactctga ttggctgagc   1980

aaacccaagg gcgggactct gcttctggca acttaaccct ttcttgggca tcccctacca   2040

cacagtaacc tcacctcaac tggacctgaa acagaggacc aagatggtgg gtctagggtc   2100

atctgaaggg agtggtccca agggtgcatg tggatgtcaa cagaaggacc acaatggtgt   2160

gagaggcctt gtgggcatgc agagactggc agcagaaagt cccaagagga gaggactcag   2220

aggcttcttc cttccaagga ggaggaggag gaggacattc cacatctggg cttccagtgg   2280

tggctcccgg acctgccttg ggggcagcag gagaggttgg gagaggtcac cctgatgaag   2340

aacaatgcca tgatctgctg ctgccagagg acatctccgc ccatccactc attttccacc   2400

tgtacacatt ggctcattca ttcgatggat atttcgggtg catctacttt atgccaggct   2460

ctatgctagg agctggggat actgtggaga aaaagtcgga tatggtctcg ctctcatcaa   2520

gatttcagtc tagctgggag tgagcgttaa ataagtcaat accaacacac acacgtgcac   2580

acacgtgatg gcaagctgtg atcatctatg aaagaaaaaa cacagatttc tttaagaggg   2640


<210>  6255
<211>  602
<212>  PRT
<213>  Homo sapiens

<400>  6255

Met Glu Arg Ser Leu His Arg Val Ser Leu Gly Ser Arg Arg Ala His 
1               5                   10                  15


Pro Asp Leu Ser Phe Tyr Leu Thr Thr Phe Gly Gln Leu Arg Leu Ser 
            20                  25                  30


Ile Asp Ala Gln Asp Arg Val Leu Leu Leu His Ile Ile Glu Gly Lys 
        35                  40                  45


Gly Leu Ile Ser Lys Gln Pro Gly Thr Cys Asp Pro Tyr Val Lys Ile 
    50                  55                  60


Ser Leu Ile Pro Glu Asp Ser Arg Leu Arg His Gln Lys Thr Gln Thr 
65                  70                  75                  80


Val Pro Asp Cys Arg Asp Pro Ala Phe His Glu His Phe Phe Phe Pro 
                85                  90                  95


Val Gln Glu Glu Asp Asp Gln Lys Arg Leu Leu Val Thr Val Trp Asn 
            100                 105                 110


Arg Ala Ser Gln Ser Arg Gln Ser Gly Leu Ile Gly Cys Met Ser Phe 
        115                 120                 125


Gly Val Lys Ser Leu Leu Thr Pro Asp Lys Glu Ile Ser Gly Trp Tyr 
    130                 135                 140


Tyr Leu Leu Gly Glu His Leu Gly Arg Thr Lys His Leu Lys Val Ala 
145                 150                 155                 160


Arg Arg Arg Leu Arg Pro Leu Arg Asp Pro Leu Leu Arg Met Pro Gly 
                165                 170                 175


Gly Gly Asp Thr Glu Asn Gly Lys Lys Leu Lys Ile Thr Ile Pro Arg 
            180                 185                 190


Gly Lys Asp Gly Phe Gly Phe Thr Ile Cys Cys Asp Ser Pro Val Arg 
        195                 200                 205


Val Gln Ala Val Asp Ser Gly Gly Pro Ala Glu Arg Ala Gly Leu Gln 
    210                 215                 220


Gln Leu Asp Thr Val Leu Gln Leu Asn Glu Arg Pro Val Glu His Trp 
225                 230                 235                 240


Lys Cys Val Glu Leu Ala His Glu Ile Arg Ser Cys Pro Ser Glu Ile 
                245                 250                 255


Ile Leu Leu Val Trp Arg Met Val Pro Gln Val Lys Pro Gly Pro Asp 
            260                 265                 270


Gly Gly Val Leu Arg Arg Ala Ser Cys Lys Ser Thr His Asp Leu Gln 
        275                 280                 285


Ser Pro Pro Asn Lys Arg Glu Lys Asn Cys Thr His Gly Val Gln Ala 
    290                 295                 300


Arg Pro Glu Gln Arg His Ser Cys His Leu Val Cys Asp Ser Ser Asp 
305                 310                 315                 320


Gly Leu Leu Leu Gly Gly Trp Glu Arg Tyr Thr Glu Val Ala Lys Arg 
                325                 330                 335


Gly Gly Gln His Thr Leu Pro Ala Leu Ser Arg Ala Thr Ala Pro Thr 
            340                 345                 350


Asp Pro Asn Tyr Ile Ile Leu Ala Pro Leu Asn Pro Gly Ser Gln Leu 
        355                 360                 365


Leu Arg Pro Val Tyr Gln Glu Asp Thr Ile Pro Glu Glu Ser Gly Ser 
    370                 375                 380


Pro Ser Lys Gly Lys Ser Tyr Thr Gly Leu Gly Lys Lys Ser Arg Leu 
385                 390                 395                 400


Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln Asn Cys 
                405                 410                 415


Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr Tyr Val 
            420                 425                 430


Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln Pro Leu 
        435                 440                 445


Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu 
    450                 455                 460


Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr 
465                 470                 475                 480


Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp 
                485                 490                 495


Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly 
            500                 505                 510


Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala 
        515                 520                 525


Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys Lys Arg 
    530                 535                 540


Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala 
545                 550                 555                 560


Ala Ser Pro Pro Asp Ser Lys Lys Leu His Pro Phe Gly Ser Leu Gln 
                565                 570                 575


Gln Glu Met Gly Pro Val Asn Ser Thr Asn Ala Thr Gln Asp Arg Ser 
            580                 585                 590


Phe Thr Ser Pro Gly Gln Thr Leu Ile Gly 
        595                 600


<210>  6256
<211>  2855
<212>  DNA
<213>  Homo sapiens

<400>  6256
ttcaaacccg cgcgggccaa tcagggccgg gcgcgccctg gccgttccaa cgcttggggc     60

agccctacct cccgctcgcg ctcctcccgc cctggagact ccggttactg gggagcaaca    120

cagccgcctc gggttgcaga cgctcctgtc cgggtcgcag tgggacgcca tggagcgctc    180

cctgcaccgc gtctccctcg ggagccggcg tgcccacccg gacttgtcct tctacctcac    240

cacctttggt cagctgaggc tgtccattga tgcccaggac cgggttctgc tgcttcacat    300

tatagaaggt aaaggcctga tcagcaaaca gcctggcacc tgtgatccgt atgtgaagat    360

ttctttgatc cctgaagata gtagactacg ccaccagaag acgcagaccg ttccagactg    420

cagagacccg gctttccacg agcacttctt ctttcctgtc caagaggagg atgatcagaa    480

gcgtctcttg gttactgtgt ggaacagggc cagccagtcc agacagagtg gactcattgg    540

ctgcatgagc tttggggtga agtctctcct gactccagac aaggagatca gtggttggta    600

ctacctccta ggggagcacc tgggccggac caagcacttg aaggtggcca ggcggcgact    660

gcggccgctg agagacccgc tgctgagaat gccaggaggt ggggacactg agaatgggaa    720

gaaactaaag atcaccatcc cgaggggaaa ggacggcttt ggcttcacca tctgctgcga    780

ctctccagtt cgagtccagg ccgtggattc cgggggtccg gcggaacggg cagggctgca    840

gcagctggac acggtgctgc agctgaatga gaggcctgtg gagcactgga aatgtgtgga    900

gctggcccac gagatccgga gctgccccag tgagatcatc ctactcgtgt ggcgcatggt    960

cccccaggtc aagccaggac cagatggcgg ggtcctgcgg cgggcctcct gcaagtcgac   1020

acatgacctc cagtcacccc ccaacaaacg ggagaagaac tgcacccatg gggtccaggc   1080

acggcctgag cagcgccaca gctgccacct ggtatgtgac agctctgatg ggctgctgct   1140

cggcggctgg gagcgctaca ccgaggtggc caagcgcggg ggccagcaca ccctgcctgc   1200

actgtcccgt gccactgccc ccaccgaccc caactacatc atcctggccc cgctgaatcc   1260

tgggagccag ctgctccggc ctgtgtacca ggaggatacc atccccgaag aatcagggag   1320

tcccagtaaa gggaagtcct acacaggcct ggggaagaag tcccggctga tgaagacagt   1380

gcagaccatg aagggccacg ggaactacca aaactgcccg gttgtgaggc cgcatgccac   1440

gcactcaagc tatggcacct acgtcaccct ggcccccaaa gtcctggtgt tccctgtctt   1500

tgttcagcct ctagatctct gtaatcctgc ccggaccctc ctgctgtcag aggagctgct   1560

gctgtatgaa gggaggaaca aggctgccga ggtgacactg tttgcctatt cggacctgct   1620

gctcttcacc aaggaggacg agcctggccg ctgcgacgtc ctgaggaacc ccctctacct   1680

ccagagtgtg aagctgcagg aaggttcttc agaagacctg aaattctgcg tgctctatct   1740

agcagagaag gcagagtgct tattcacttt ggaagcgcac tcgcaggagc agaagaagag   1800

agtgtgctgg tgcctgtcgg agaacatcgc caagcagcaa cagctggcag catcaccccc   1860

ggacagcaag aaactccacc ctttcggctc tctccagcag gagatggggc cggtcaactc   1920

aaccaatgcc acccaggata gaagctttac ctcaccagga cagactctga ttggctgagc   1980

aaacccaagg gcgggactct gcttctggca acttaaccct ttcttgggca tcccctacca   2040

cacagtaacc tcacctcaac tggacctgaa acagaggacc aagatggtgg gtctagggtc   2100

atctgaaggg agtggtccca agggtgcatg tggatgtcaa cagaaggacc acaatggtgt   2160

gagaggcctt gtgggcatgc agagactggc agcagaaagt cccaagagga gaggactcag   2220

aggcttcttc cttccaagga ggaggaggag gaggacattc cacatctggg cttccagtgg   2280

tggctcccgg acctgccttg ggggcagcag gagaggttgg gagaggtcac cctgatgaag   2340

aacaatgcca tgatctgctg ctgccagagg acatctccgc ccatccactc attttccacc   2400

tgtacacatt ggctcattca ttcgatggat atttcgggtg catctacttt atgccaggct   2460

ctatgctagg agctggggat actgtggaga aaaagtcgga tatggtctcg ctctcatcaa   2520

gatttcagtc tagctgggag tgagcgttaa ataagtcaat accaacacac acacgtgcac   2580

acacgtgatg gcaagctgtg atcatctatg aaagaaaaaa cacagatttc tttaagaggg   2640

aattgtactt agagtgctgt gtgtgggggt ggggatgggg aaggacataa cttttaaacc   2700

gagacttgtg ggctggagag gaaggagcca gtcctggact tggggaagag tgttcgcggt   2760

ggatggaata gcacgtggag agtccctgag atgggaagga gctcagtggg ctggaggaat   2820

ggcgagcagg ccagtgtggc tggagcttag tgagg                              2855


<210>  6257
<211>  602
<212>  PRT
<213>  Homo sapiens

<400>  6257

Met Glu Arg Ser Leu His Arg Val Ser Leu Gly Ser Arg Arg Ala His 
1               5                   10                  15


Pro Asp Leu Ser Phe Tyr Leu Thr Thr Phe Gly Gln Leu Arg Leu Ser 
            20                  25                  30


Ile Asp Ala Gln Asp Arg Val Leu Leu Leu His Ile Ile Glu Gly Lys 
        35                  40                  45


Gly Leu Ile Ser Lys Gln Pro Gly Thr Cys Asp Pro Tyr Val Lys Ile 
    50                  55                  60


Ser Leu Ile Pro Glu Asp Ser Arg Leu Arg His Gln Lys Thr Gln Thr 
65                  70                  75                  80


Val Pro Asp Cys Arg Asp Pro Ala Phe His Glu His Phe Phe Phe Pro 
                85                  90                  95


Val Gln Glu Glu Asp Asp Gln Lys Arg Leu Leu Val Thr Val Trp Asn 
            100                 105                 110


Arg Ala Ser Gln Ser Arg Gln Ser Gly Leu Ile Gly Cys Met Ser Phe 
        115                 120                 125


Gly Val Lys Ser Leu Leu Thr Pro Asp Lys Glu Ile Ser Gly Trp Tyr 
    130                 135                 140


Tyr Leu Leu Gly Glu His Leu Gly Arg Thr Lys His Leu Lys Val Ala 
145                 150                 155                 160


Arg Arg Arg Leu Arg Pro Leu Arg Asp Pro Leu Leu Arg Met Pro Gly 
                165                 170                 175


Gly Gly Asp Thr Glu Asn Gly Lys Lys Leu Lys Ile Thr Ile Pro Arg 
            180                 185                 190


Gly Lys Asp Gly Phe Gly Phe Thr Ile Cys Cys Asp Ser Pro Val Arg 
        195                 200                 205


Val Gln Ala Val Asp Ser Gly Gly Pro Ala Glu Arg Ala Gly Leu Gln 
    210                 215                 220


Gln Leu Asp Thr Val Leu Gln Leu Asn Glu Arg Pro Val Glu His Trp 
225                 230                 235                 240


Lys Cys Val Glu Leu Ala His Glu Ile Arg Ser Cys Pro Ser Glu Ile 
                245                 250                 255


Ile Leu Leu Val Trp Arg Met Val Pro Gln Val Lys Pro Gly Pro Asp 
            260                 265                 270


Gly Gly Val Leu Arg Arg Ala Ser Cys Lys Ser Thr His Asp Leu Gln 
        275                 280                 285


Ser Pro Pro Asn Lys Arg Glu Lys Asn Cys Thr His Gly Val Gln Ala 
    290                 295                 300


Arg Pro Glu Gln Arg His Ser Cys His Leu Val Cys Asp Ser Ser Asp 
305                 310                 315                 320


Gly Leu Leu Leu Gly Gly Trp Glu Arg Tyr Thr Glu Val Ala Lys Arg 
                325                 330                 335


Gly Gly Gln His Thr Leu Pro Ala Leu Ser Arg Ala Thr Ala Pro Thr 
            340                 345                 350


Asp Pro Asn Tyr Ile Ile Leu Ala Pro Leu Asn Pro Gly Ser Gln Leu 
        355                 360                 365


Leu Arg Pro Val Tyr Gln Glu Asp Thr Ile Pro Glu Glu Ser Gly Ser 
    370                 375                 380


Pro Ser Lys Gly Lys Ser Tyr Thr Gly Leu Gly Lys Lys Ser Arg Leu 
385                 390                 395                 400


Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln Asn Cys 
                405                 410                 415


Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr Tyr Val 
            420                 425                 430


Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln Pro Leu 
        435                 440                 445


Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu 
    450                 455                 460


Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr 
465                 470                 475                 480


Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp 
                485                 490                 495


Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly 
            500                 505                 510


Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala 
        515                 520                 525


Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys Lys Arg 
    530                 535                 540


Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala 
545                 550                 555                 560


Ala Ser Pro Pro Asp Ser Lys Lys Leu His Pro Phe Gly Ser Leu Gln 
                565                 570                 575


Gln Glu Met Gly Pro Val Asn Ser Thr Asn Ala Thr Gln Asp Arg Ser 
            580                 585                 590


Phe Thr Ser Pro Gly Gln Thr Leu Ile Gly 
        595                 600


<210>  6258
<211>  4231
<212>  DNA
<213>  Homo sapiens

<400>  6258
agactccggt tactggggag caacacagcc gcctcgggtt gcagacgctc ctgtccgggt     60

cgcagtggga cgccatggag cgctccctgc accgcgtctc cctcgggagc cggcgtgccc    120

acccggactt gtccttctac ctcaccacct ttggtcagct gaggctgtcc attgatgccc    180

aggaccgggt tctgctgctt cacagtctct ttattcgtgt ggatggatat gtctatgtgt    240

gtctctcttt ctcgctgtgt gtgtgtgtat gtttccattc atccacccca atgtctgaat    300

tctcttttag ttatagaagg taaaggcctg atcagcaaac agcctggcac ctgtgatccg    360

tatgtgaaga tttctttgat ccctgaagat agtagactac gccaccagaa gacgcagacc    420

gttccagact gcagagaccc ggctttccac gagcacttct tctttcctgt ccaagaggag    480

gatgatcaga agcgtctctt ggttactgtg tggaacaggg ccagccagtc cagacagagt    540

ggactcattg gctgcatgag ctttggggtg aagtctctcc tgactccaga caaggagatc    600

agtggttggt actacctcct aggggagcac ctgggccgga ccaagcactt gaaggtggcc    660

aggcggcgac tgcggccgct gagagacccg ctgctgagaa tgccaggagg tggggacact    720

gagaatggga agaaactaaa gatcaccatc ccgaggggaa aggacggctt tggcttcacc    780

atctgctgcg actctccagt tcgagtccag gccgtggatt ccgggggtcc ggcggaacgg    840

gcagggctgc agcagctgga cacggtgctg cagctgaatg agaggcctgt ggagcactgg    900

aaatgtgtgg agctggccca cgagatccgg agctgcccca gtgagatcat cctactcgtg    960

tggcgcatgg tcccccaggt caagccagga ccagatggcg gggtcctgcg gcgggcctcc   1020

tgcaagtcga cacatgacct ccagtcaccc cccaacaaac gggagaagaa ctgcacccat   1080

ggggtccagg cacggcctga gcagcgccac agctgccacc tggtatgtga cagctctgat   1140

gggctgctgc tcggcggctg ggagcgctac accgaggtgg ccaagcgcgg gggccagcac   1200

accctgcctg cactgtcccg tgccactgcc cccaccgacc ccaactacat catcctggcc   1260

ccgctgaatc ctgggagcca gctgctccgg cctgtgtacc aggaggatac catccccgaa   1320

gaatcaggga gtcccagtaa agggaagtcc tacacaggcc tggggaagaa gtcccggctg   1380

atgaagacag tgcagaccat gaagggccac gggaactacc aaaactgccc ggttgtgagg   1440

ccgcatgcca cgcactcaag ctatggcacc tacgtcaccc tggcccccaa agtcctggtg   1500

ttccctgtct ttgttcagcc tctagatctc tgtaatcctg cccggaccct cctgctgtca   1560

gaggagctgc tgctgtatga agggaggaac aaggctgccg aggtgacact gtttgcctat   1620

tcggacctgc tgctcttcac caaggaggac gagcctggcc gctgcgacgt cctgaggaac   1680

cccctctacc tccagagtgt gaagctgcag gaaggttctt cagaagacct gaaattctgc   1740

gtgctctatc tagcagagaa ggcagagtgc ttattcactt tggaagcgca ctcgcaggag   1800

cagaagaaga gagtgtgctg gtgcctgtcg gagaacatcg ccaagcagca acagctggca   1860

gcatcacccc cggacagcaa gatgtttgag acggaggcag atgagaagag ggagatggcc   1920

ttggaggaag ggaaggggcc tggtgccgag gattccccac ccagcaagga gccctctcct   1980

ggccaggagc ttcctccagg acaagacctt ccacccaaca aggactcccc ttctgggcag   2040

gaacccgctc ccagccaaga accactgtcc agcaaagact cagctacctc tgaaggatcc   2100

cctccaggcc cagatgctcc gcccagcaag gatgtgccac catgccagga accccctcca   2160

gcccaagacc tctcaccctg ccaggaccta cctgctggtc aagaacccct gcctcaccag   2220

gaccctctac tcaccaaaga cctccctgcc atccaggaat cccccacccg ggaccttcca   2280

ccctgtcaag atctgcctcc tagccaggtc tccctgccag ccaaggccct tactgaggac   2340

accatgagct ccggggacct actagcagct actggggacc cacctgcggc ccccaggcca   2400

gccttcgtga tccctgaggt ccggctggat agcacctaca gccagaaggc aggggcagag   2460

cagggctgct cgggagatga ggaggatgca gaagaggccg aggaggtgga ggagggggag   2520

gaaggggagg aggacgagga tgaggacacc agcgatgaca actacggaga gcgcagtgag   2580

gccaagcgca gcagcatgat cgagacgggc cagggggctg agggtggcct ctcactgcgt   2640

gtgcagaact cgctgcggcg ccggacgcac agcgagggca gcctgctgca ggagccccga   2700

gggccctgct ttgcctccga caccaccttg cactgctcag acggtgaggg cgccgcctcc   2760

acctggggca tgccttcgcc cagcaccctc aagaaagagc tgggccgcaa tggtggctcc   2820

atgcaccacc tttccctctt cttcacagga cacaggaaga tgagcggggc tgacaccgtt   2880

ggggatgatg acgaagcctc ccggaagaga aagagcaaaa acctagccaa ggacatgaag   2940

aacaagctgg ggatcttcag acggcggaat gagtcccctg gagcccctcc cgcgggcaag   3000

gcagacaaaa tgatgaagtc attcaagccc acctcagagg aagccctcaa gtggggcgag   3060

tccttggaga agctgctggt tcacaaatac gggttagcag tgttccaagc cttccttcgc   3120

actgagttca gtgaggagaa tctggagttc tggttggctt gtgaggactt caagaaggtc   3180

aagtcacagt ccaagatggc atccaaggcc aagaagatct ttgctgaata catcgcgatc   3240

caggcatgca aggaggtcaa cctggactcc tacacgcggg agcacaccaa ggacaacctg   3300

cagagcgtca cgcggggctg cttcgacctg gcacagaagc gcatcttcgg gctcatggaa   3360

aaggactcgt accctcgctt tctccgttct gacctctacc tggaccttat taaccagaag   3420

aagatgagtc ccccgcttta ggggccactg gagtcgagct cagcgttcac accaggcggg   3480

ctgggtcccc tgcccacctg cctccctgcc ccctgtgacg gagggggcaa gcaagccccc   3540

agaggctgtg tctctggaca gacggataga catacggaag cgaggcctgg accaagagag   3600

gcccaggcta ctggaggagt agaaggatgg gccccgtggg gtccccactg ccccggtacg   3660

agggggccca agaccctggc aggtcagggg ccctggccaa gccagatctg gagctgctgc   3720

tccctgctgc ggagaccgcg gaggcttcgc gttgaccaag ttccttaaag aactggctga   3780

tggggcagga ggtccaggcc tgggctctcg ggccctccta gagggccatt ggagcttgca   3840

gctcagaccc ccactttgag ttttatttat ttaaatagta gttggatgct tggcacgtcg   3900

tcctgtaata ggaaaccctt gcctcatcag ttttcctgat ttacaagtgc aatattttag   3960

ccaatgcctt gggagaagct gccatgcaaa ggtggacacc attctccagc ttcaggggat   4020

atgctcgtcc cgggcaccgg tggcaggcag ctggccttct ggactaaggc agcctggggg   4080

gacactgcag tctggctaca cacagagatc tggcaccccc tgggtggagt gtccctcggg   4140

ggctttggga aagcatggca ccctcagacc acacagtagc caagttctgg agcaaataaa   4200

aggcctgtgt tatttcttgt tcttgaccct t                                  4231


<210>  6259
<211>  1088
<212>  PRT
<213>  Homo sapiens

<400>  6259

Met Pro Arg Thr Gly Phe Cys Cys Phe Thr Val Ser Leu Phe Val Trp 
1               5                   10                  15


Met Asp Met Ser Met Cys Val Ser Leu Ser Arg Cys Val Cys Val Tyr 
            20                  25                  30


Val Ser Ile His Pro Pro Gln Cys Leu Asn Ser Leu Leu Val Ile Glu 
        35                  40                  45


Gly Lys Gly Leu Ile Ser Lys Gln Pro Gly Thr Cys Asp Pro Tyr Val 
    50                  55                  60


Lys Ile Ser Leu Ile Pro Glu Asp Ser Arg Leu Arg His Gln Lys Thr 
65                  70                  75                  80


Gln Thr Val Pro Asp Cys Arg Asp Pro Ala Phe His Glu His Phe Phe 
                85                  90                  95


Phe Pro Val Gln Glu Glu Asp Asp Gln Lys Arg Leu Leu Val Thr Val 
            100                 105                 110


Trp Asn Arg Ala Ser Gln Ser Arg Gln Ser Gly Leu Ile Gly Cys Met 
        115                 120                 125


Ser Phe Gly Val Lys Ser Leu Leu Thr Pro Asp Lys Glu Ile Ser Gly 
    130                 135                 140


Trp Tyr Tyr Leu Leu Gly Glu His Leu Gly Arg Thr Lys His Leu Lys 
145                 150                 155                 160


Val Ala Arg Arg Arg Leu Arg Pro Leu Arg Asp Pro Leu Leu Arg Met 
                165                 170                 175


Pro Gly Gly Gly Asp Thr Glu Asn Gly Lys Lys Leu Lys Ile Thr Ile 
            180                 185                 190


Pro Arg Gly Lys Asp Gly Phe Gly Phe Thr Ile Cys Cys Asp Ser Pro 
        195                 200                 205


Val Arg Val Gln Ala Val Asp Ser Gly Gly Pro Ala Glu Arg Ala Gly 
    210                 215                 220


Leu Gln Gln Leu Asp Thr Val Leu Gln Leu Asn Glu Arg Pro Val Glu 
225                 230                 235                 240


His Trp Lys Cys Val Glu Leu Ala His Glu Ile Arg Ser Cys Pro Ser 
                245                 250                 255


Glu Ile Ile Leu Leu Val Trp Arg Met Val Pro Gln Val Lys Pro Gly 
            260                 265                 270


Pro Asp Gly Gly Val Leu Arg Arg Ala Ser Cys Lys Ser Thr His Asp 
        275                 280                 285


Leu Gln Ser Pro Pro Asn Lys Arg Glu Lys Asn Cys Thr His Gly Val 
    290                 295                 300


Gln Ala Arg Pro Glu Gln Arg His Ser Cys His Leu Val Cys Asp Ser 
305                 310                 315                 320


Ser Asp Gly Leu Leu Leu Gly Gly Trp Glu Arg Tyr Thr Glu Val Ala 
                325                 330                 335


Lys Arg Gly Gly Gln His Thr Leu Pro Ala Leu Ser Arg Ala Thr Ala 
            340                 345                 350


Pro Thr Asp Pro Asn Tyr Ile Ile Leu Ala Pro Leu Asn Pro Gly Ser 
        355                 360                 365


Gln Leu Leu Arg Pro Val Tyr Gln Glu Asp Thr Ile Pro Glu Glu Ser 
    370                 375                 380


Gly Ser Pro Ser Lys Gly Lys Ser Tyr Thr Gly Leu Gly Lys Lys Ser 
385                 390                 395                 400


Arg Leu Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln 
                405                 410                 415


Asn Cys Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr 
            420                 425                 430


Tyr Val Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln 
        435                 440                 445


Pro Leu Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu 
    450                 455                 460


Leu Leu Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe 
465                 470                 475                 480


Ala Tyr Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg 
                485                 490                 495


Cys Asp Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln 
            500                 505                 510


Glu Gly Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu 
        515                 520                 525


Lys Ala Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys 
    530                 535                 540


Lys Arg Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln 
545                 550                 555                 560


Leu Ala Ala Ser Pro Pro Asp Ser Lys Met Phe Glu Thr Glu Ala Asp 
                565                 570                 575


Glu Lys Arg Glu Met Ala Leu Glu Glu Gly Lys Gly Pro Gly Ala Glu 
            580                 585                 590


Asp Ser Pro Pro Ser Lys Glu Pro Ser Pro Gly Gln Glu Leu Pro Pro 
        595                 600                 605


Gly Gln Asp Leu Pro Pro Asn Lys Asp Ser Pro Ser Gly Gln Glu Pro 
    610                 615                 620


Ala Pro Ser Gln Glu Pro Leu Ser Ser Lys Asp Ser Ala Thr Ser Glu 
625                 630                 635                 640


Gly Ser Pro Pro Gly Pro Asp Ala Pro Pro Ser Lys Asp Val Pro Pro 
                645                 650                 655


Cys Gln Glu Pro Pro Pro Ala Gln Asp Leu Ser Pro Cys Gln Asp Leu 
            660                 665                 670


Pro Ala Gly Gln Glu Pro Leu Pro His Gln Asp Pro Leu Leu Thr Lys 
        675                 680                 685


Asp Leu Pro Ala Ile Gln Glu Ser Pro Thr Arg Asp Leu Pro Pro Cys 
    690                 695                 700


Gln Asp Leu Pro Pro Ser Gln Val Ser Leu Pro Ala Lys Ala Leu Thr 
705                 710                 715                 720


Glu Asp Thr Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro 
                725                 730                 735


Pro Ala Ala Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp 
            740                 745                 750


Ser Thr Tyr Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp 
        755                 760                 765


Glu Glu Asp Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly 
    770                 775                 780


Glu Glu Asp Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg 
785                 790                 795                 800


Ser Glu Ala Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu 
                805                 810                 815


Gly Gly Leu Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His 
            820                 825                 830


Ser Glu Gly Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser 
        835                 840                 845


Asp Thr Thr Leu His Cys Ser Asp Gly Glu Gly Ala Ala Ser Thr Trp 
    850                 855                 860


Gly Met Pro Ser Pro Ser Thr Leu Lys Lys Glu Leu Gly Arg Asn Gly 
865                 870                 875                 880


Gly Ser Met His His Leu Ser Leu Phe Phe Thr Gly His Arg Lys Met 
                885                 890                 895


Ser Gly Ala Asp Thr Val Gly Asp Asp Asp Glu Ala Ser Arg Lys Arg 
            900                 905                 910


Lys Ser Lys Asn Leu Ala Lys Asp Met Lys Asn Lys Leu Gly Ile Phe 
        915                 920                 925


Arg Arg Arg Asn Glu Ser Pro Gly Ala Pro Pro Ala Gly Lys Ala Asp 
    930                 935                 940


Lys Met Met Lys Ser Phe Lys Pro Thr Ser Glu Glu Ala Leu Lys Trp 
945                 950                 955                 960


Gly Glu Ser Leu Glu Lys Leu Leu Val His Lys Tyr Gly Leu Ala Val 
                965                 970                 975


Phe Gln Ala Phe Leu Arg Thr Glu Phe Ser Glu Glu Asn Leu Glu Phe 
            980                 985                 990


Trp Leu Ala Cys Glu Asp Phe Lys Lys Val Lys Ser Gln Ser Lys Met 
        995                 1000                1005


Ala Ser Lys Ala Lys Lys Ile Phe Ala Glu Tyr Ile Ala Ile Gln Ala 
    1010                1015                1020


Cys Lys Glu Val Asn Leu Asp Ser Tyr Thr Arg Glu His Thr Lys Asp 
1025                1030                1035                1040


Asn Leu Gln Ser Val Thr Arg Gly Cys Phe Asp Leu Ala Gln Lys Arg 
                1045                1050                1055


Ile Phe Gly Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Arg Ser 
            1060                1065                1070


Asp Leu Tyr Leu Asp Leu Ile Asn Gln Lys Lys Met Ser Pro Pro Leu 
        1075                1080                1085


<210>  6260
<211>  679
<212>  DNA
<213>  Homo sapiens

<400>  6260
gaggtttcag gaagccttcg ggcttatcgt gcagaggcac acagcacaga cagggcttgg     60

ggagggcccg ccccaggcta acgctctgtg aacctctgtg agaaaggaag aagggagcca    120

ggaaaacagt ggatcaaaga tcaccatccc gaggggaaag gacggctttg gcttcaccat    180

ctgctgcgac tctccagttc gagtccaggc cgtggattcc gggggtccgg cggaacgggc    240

agggctgcag cagctggaca cggtgctgca gctgaatgag aggcctgtgg agcactggaa    300

atgtgtggag ctggcccacg agatccggag ctgccccagt gagatcatcc tactcgtgtg    360

gcgcatggtc ccccaggtca agccaggacc agatggcggg gtcctgcggc gggcctcctg    420

caagtcgaca catgacctcc agtcaccccc caacaaacgg gagaagaact gcacccatgg    480

ggtccaggca cggcctgagc agcgccacag ctgccacctg gtatgtgaca gctctgatgg    540

gctgctgctc ggcggctggg agcgctacac cgaggtggcc aagcgcgggg gccagcacac    600

cctgcctgca ctgtcccgtg ccactgcccc caccgacccc aactacatca tcctggcccc    660

gctgaatcct gggagccag                                                 679


<210>  6261
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  6261

Met Arg Gly Leu Trp Ser Thr Gly Asn Val Trp Ser Trp Pro Thr Arg 
1               5                   10                  15


Ser Gly Ala Ala Pro Val Arg Ser Ser Tyr Ser Cys Gly Ala Trp Ser 
            20                  25                  30


Pro Arg Ser Ser Gln Asp Gln Met Ala Gly Ser Cys Gly Gly Pro Pro 
        35                  40                  45


Ala Ser Arg His Met Thr Ser Ser His Pro Pro Thr Asn Gly Arg Arg 
    50                  55                  60


Thr Ala Pro Met Gly Ser Arg His Gly Leu Ser Ser Ala Thr Ala Ala 
65                  70                  75                  80


Thr Trp Tyr Val Thr Ala Leu Met Gly Cys Cys Ser Ala Ala Gly Ser 
                85                  90                  95


Ala Thr Pro Arg Trp Pro Ser Ala Gly Ala Ser Thr Pro Cys Leu His 
            100                 105                 110


Cys Pro Val Pro Leu Pro Pro Pro Thr Pro Thr Thr Ser Ser Trp Pro 
        115                 120                 125


Arg 



<210>  6262
<211>  3694
<212>  DNA
<213>  Homo sapiens

<400>  6262
ttggggaggt gagaggtgat ttcctgccat tcttctgtgg ggcgggcttc ccagggtgct     60

catgccaggc tgacgggtcc agtgcgggct cccgctgctg ggggagagct gggttttcat    120

ggggcggcag ccgaggcagg acccgcagcc atgaaccgct tcaatgggct ctgcaaggtg    180

tgctcggagc gccgctaccg ccagatcacc atcccgaggg gaaaggacgg ctttggcttc    240

accatctgct gcgactctcc agttcgagtc caggccgtgg attccggggg tccggcggaa    300

cgggcagggc tgcagcagct ggacacggtg ctgcagctga atgagaggcc tgtggagcac    360

tggaaatgtg tggagctggc ccacgagatc cggagctgcc ccagtgagat catcctactc    420

gtgtggcgca tggtccccca ggtcaagcca ggaccagatg gcggggtcct gcggcgggcc    480

tcctgcaagt cgacacatga cctccagtca ccccccaaca aacgggagaa gaactgcacc    540

catggggtcc aggcacggcc tgagcagcgc cacagctgcc acctggtatg tgacagctct    600

gatgggctgc tgctcggcgg ctgggagcgc tacaccgagg tggccaagcg cgggggccag    660

cacaccctgc ctgcactgtc ccgtgccact gcccccaccg accccaacta catcatcctg    720

gccccgctga atcctgggag ccagctgctc cggcctgtgt accaggagga taccatcccc    780

gaagaatcag ggagtcccag taaagggaag tcctacacag gcctggggaa gaagtcccgg    840

ctgatgaaga cagtgcagac catgaagggc cacgggaact accaaaactg cccggttgtg    900

aggccgcatg ccacgcactc aagctatggc acctacgtca ccctggcccc caaagtcctg    960

gtgttccctg tctttgttca gcctctagat ctctgtaatc ctgcccggac cctcctgctg   1020

tcagaggagc tgctgctgta tgaagggagg aacaaggctg ccgaggtgac actgtttgcc   1080

tattcggacc tgctgctctt caccaaggag gacgagcctg gccgctgcga cgtcctgagg   1140

aaccccctct acctccagag tgtgaagctg caggaaggtt cttcagaaga cctgaaattc   1200

tgcgtgctct atctagcaga gaaggcagag tgcttattca ctttggaagc gcactcgcag   1260

gagcagaaga agagagtgtg ctggtgcctg tcggagaaca tcgccaagca gcaacagctg   1320

gcagcatcac ccccggacag caagatgttt gagacggagg cagatgagaa gagggagatg   1380

gccttggagg aagggaaggg gcctggtgcc gaggattccc cacccagcaa ggagccctct   1440

cctggccagg agcttcctcc aggacaagac cttccaccca acaaggactc cccttctggg   1500

caggaacccg ctcccagcca agaaccactg tccagcaaag actcagctac ctctgaagga   1560

tcccctccag gcccagatgc tccgcccagc aaggatgtgc caccatgcca ggaaccccct   1620

ccagcccaag acctctcacc ctgccaggac ctacctgctg gtcaagaacc cctgcctcac   1680

caggaccctc tactcaccaa agacctccct gccatccagg aatcccccac ccgggacctt   1740

ccaccctgtc aagatctgcc tcctagccag gtctccctgc cagccaaggc ccttactgag   1800

gacaccatga gctccgggga cctactagca gctactgggg acccacctgc ggcccccagg   1860

ccagccttcg tgatccctga ggtccggctg gatagcacct acagccagaa ggcaggggca   1920

gagcagggct gctcgggaga tgaggaggat gcagaagagg ccgaggaggt ggaggagggg   1980

gaggaagggg aggaggacga ggatgaggac accagcgatg acaactacgg agagcgcagt   2040

gaggccaagc gcagcagcat gatcgagacg ggccaggggg ctgagggtgg cctctcactg   2100

cgtgtgcaga actcgctgcg gcgccggacg cacagcgagg gcagcctgct gcaggagccc   2160

cgagggccct gctttgcctc cgacaccacc ttgcactgct cagacggtga gggcgccgcc   2220

tccacctggg gcatgccttc gcccagcacc ctcaagaaag agctgggccg caatggtggc   2280

tccatgcacc acctttccct cttcttcaca ggacacagga agatgagcgg ggctgacacc   2340

gttggggatg atgacgaagc ctcccggaag agaaagagca aaaacctagc caaggacatg   2400

aagaacaagc tggggatctt cagacggcgg aatgagtccc ctggagcccc tcccgcgggc   2460

aaggcagaca aaatgatgaa gtcattcaag cccacctcag aggaagccct caagtggggc   2520

gagtccttgg agaagctgct ggttcacaaa tacgggttag cagtgttcca agccttcctt   2580

cgcactgagt tcagtgagga gaatctggag ttctggttgg cttgtgagga cttcaagaag   2640

gtcaagtcac agtccaagat ggcatccaag gccaagaaga tctttgctga atacatcgcg   2700

atccaggcat gcaaggaggt caacctggac tcctacacgc gggagcacac caaggacaac   2760

ctgcagagcg tcacgcgggg ctgcttcgac ctggcacaga agcgcatctt cgggctcatg   2820

gaaaaggact cgtaccctcg ctttctccgt tctgacctct acctggacct tattaaccag   2880

aagaagatga gtcccccgct ttaggggcca ctggagtcga gctcagcgtt cacaccaggc   2940

gggctgggtc ccctgcccac ctgcctccct gccccctgtg acggaggggg caagcaagcc   3000

cccagaggct gtgtctctgg acagacggat agacatacgg aagcgaggcc tggaccaaga   3060

gaggcccagg ctactggagg agtagaagga tgggccccgt ggggtcccca ctgccccggt   3120

acgagggggc ccaagaccct ggcaggtcag gggccctggc caagccagat ctggagctgc   3180

tgctccctgc tgcggagacc gcggaggctt cgcgttgacc aagttcctta aagaactggc   3240

tgatggggca ggaggtccag gcctgggctc tcgggccctc ctagagggcc attggagctt   3300

gcagctcaga cccccacttt gagttttatt tatttaaata gtagttggat gcttggcacg   3360

tcgtcctgta ataggaaacc cttgcctcat cagttttcct gatttacaag tgcaatattt   3420

tagccaatgc cttgggagaa gctgccatgc aaaggtggac accattctcc agcttcaggg   3480

gatatgctcg tcccgggcac cggtggcagg cagctggcct tctggactaa ggcagcctgg   3540

ggggacactg cagtctggct acacacagag atctggcacc ccctgggtgg agtgtccctc   3600

gggggctttg ggaaagcatg gcaccctcag accacacagt agccaagttc tggagcaaat   3660

aaaaggcctg tgttatttct tgttcttgac cctt                               3694


<210>  6263
<211>  917
<212>  PRT
<213>  Homo sapiens

<400>  6263

Met Asn Arg Phe Asn Gly Leu Cys Lys Val Cys Ser Glu Arg Arg Tyr 
1               5                   10                  15


Arg Gln Ile Thr Ile Pro Arg Gly Lys Asp Gly Phe Gly Phe Thr Ile 
            20                  25                  30


Cys Cys Asp Ser Pro Val Arg Val Gln Ala Val Asp Ser Gly Gly Pro 
        35                  40                  45


Ala Glu Arg Ala Gly Leu Gln Gln Leu Asp Thr Val Leu Gln Leu Asn 
    50                  55                  60


Glu Arg Pro Val Glu His Trp Lys Cys Val Glu Leu Ala His Glu Ile 
65                  70                  75                  80


Arg Ser Cys Pro Ser Glu Ile Ile Leu Leu Val Trp Arg Met Val Pro 
                85                  90                  95


Gln Val Lys Pro Gly Pro Asp Gly Gly Val Leu Arg Arg Ala Ser Cys 
            100                 105                 110


Lys Ser Thr His Asp Leu Gln Ser Pro Pro Asn Lys Arg Glu Lys Asn 
        115                 120                 125


Cys Thr His Gly Val Gln Ala Arg Pro Glu Gln Arg His Ser Cys His 
    130                 135                 140


Leu Val Cys Asp Ser Ser Asp Gly Leu Leu Leu Gly Gly Trp Glu Arg 
145                 150                 155                 160


Tyr Thr Glu Val Ala Lys Arg Gly Gly Gln His Thr Leu Pro Ala Leu 
                165                 170                 175


Ser Arg Ala Thr Ala Pro Thr Asp Pro Asn Tyr Ile Ile Leu Ala Pro 
            180                 185                 190


Leu Asn Pro Gly Ser Gln Leu Leu Arg Pro Val Tyr Gln Glu Asp Thr 
        195                 200                 205


Ile Pro Glu Glu Ser Gly Ser Pro Ser Lys Gly Lys Ser Tyr Thr Gly 
    210                 215                 220


Leu Gly Lys Lys Ser Arg Leu Met Lys Thr Val Gln Thr Met Lys Gly 
225                 230                 235                 240


His Gly Asn Tyr Gln Asn Cys Pro Val Val Arg Pro His Ala Thr His 
                245                 250                 255


Ser Ser Tyr Gly Thr Tyr Val Thr Leu Ala Pro Lys Val Leu Val Phe 
            260                 265                 270


Pro Val Phe Val Gln Pro Leu Asp Leu Cys Asn Pro Ala Arg Thr Leu 
        275                 280                 285


Leu Leu Ser Glu Glu Leu Leu Leu Tyr Glu Gly Arg Asn Lys Ala Ala 
    290                 295                 300


Glu Val Thr Leu Phe Ala Tyr Ser Asp Leu Leu Leu Phe Thr Lys Glu 
305                 310                 315                 320


Asp Glu Pro Gly Arg Cys Asp Val Leu Arg Asn Pro Leu Tyr Leu Gln 
                325                 330                 335


Ser Val Lys Leu Gln Glu Gly Ser Ser Glu Asp Leu Lys Phe Cys Val 
            340                 345                 350


Leu Tyr Leu Ala Glu Lys Ala Glu Cys Leu Phe Thr Leu Glu Ala His 
        355                 360                 365


Ser Gln Glu Gln Lys Lys Arg Val Cys Trp Cys Leu Ser Glu Asn Ile 
    370                 375                 380


Ala Lys Gln Gln Gln Leu Ala Ala Ser Pro Pro Asp Ser Lys Met Phe 
385                 390                 395                 400


Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu Gly Lys 
                405                 410                 415


Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser Pro Gly 
            420                 425                 430


Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp Ser Pro 
        435                 440                 445


Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser Lys Asp 
    450                 455                 460


Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro Pro Ser 
465                 470                 475                 480


Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp Leu Ser 
                485                 490                 495


Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His Gln Asp 
            500                 505                 510


Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro Thr Arg 
        515                 520                 525


Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser Leu Pro 
    530                 535                 540


Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu Leu Ala 
545                 550                 555                 560


Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val Ile Pro 
                565                 570                 575


Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala Glu Gln 
            580                 585                 590


Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu Val Glu 
        595                 600                 605


Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser Asp Asp 
    610                 615                 620


Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile Glu Thr 
625                 630                 635                 640


Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn Ser Leu 
                645                 650                 655


Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro Arg Gly 
            660                 665                 670


Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly Glu Gly 
        675                 680                 685


Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr Leu Lys Lys Glu 
    690                 695                 700


Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser Leu Phe Phe Thr 
705                 710                 715                 720


Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly Asp Asp Asp Glu 
                725                 730                 735


Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Ala Lys Asp Met Lys Asn 
            740                 745                 750


Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly Ala Pro Pro 
        755                 760                 765


Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro Thr Ser Glu 
    770                 775                 780


Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu Val His Lys 
785                 790                 795                 800


Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu Phe Ser Glu 
                805                 810                 815


Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys Lys Val Lys 
            820                 825                 830


Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe Ala Glu Tyr 
        835                 840                 845


Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr Thr Arg 
    850                 855                 860


Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly Cys Phe Asp 
865                 870                 875                 880


Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp Ser Tyr Pro 
                885                 890                 895


Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln Lys Lys 
            900                 905                 910


Met Ser Pro Pro Leu 
        915


<210>  6264
<211>  2664
<212>  DNA
<213>  Homo sapiens

<400>  6264
agggtgctca tgccaggctg acgggtccag tgcgggctcc cgctgctggg ggagagctgg     60

gttttcatgg ggcggcagcc gaggcaggac ccgcagccat gaaccgcttc aatgggctct    120

gcaaggtgtg ctcggagcgc cgctaccgcc agatcaccat cccgagggga aaggacggct    180

ttggcttcac catctgctgc gactctccag ttcgagtcca ggccgtggat tccgggggtc    240

cggcggaacg ggcagggctg cagcagctgg acacggtgct gcagctgaat gagaggcctg    300

tggagcactg gaaatgtgtg gagctggccc acgagatccg gagctgcccc agtgagatca    360

tcctactcgt gtggcgcatg gtcccccagg tcaagccagg accagatggc ggggtcctgc    420

ggcgggcctc ctgcaagtcg acacatgacc tccagtcacc ccccaacaaa cgggagaaga    480

actgcaccca tggggtccag gcacggcctg agcagcgcca cagctgccac ctggtatgtg    540

acagctctga tgggctgctg ctcggcggct gggagcgcta caccgaggtg gccaagcgcg    600

ggggccagca caccctgcct gcactgtccc gtgccactgc ccccaccgac cccaactaca    660

tcatcctggc cccgctgaat cctgggagcc agctgctccg gcctgtgtac caggaggata    720

ccatccccga agaatcaggg agtcccagta aagggaagtc ctacacaggc ctggggaaga    780

agtcccggct gatgaagaca gtgcagacca tgaagggcca cgggaactac caaaactgcc    840

cggttgtgag gccgcatgcc acgcactcaa gctatggcac ctacgtcacc ctggccccca    900

aagtcctggt gttccctgtc tttgttcagc ctctagatct ctgtaatcct gcccggaccc    960

tcctgctgtc agaggagctg ctgctgtatg aagggaggaa caaggctgcc gaggtgacac   1020

tgtttgccta ttcggacctg ctgctcttca ccaaggagga cgagcctggc cgctgcgacg   1080

tcctgaggaa ccccctctac ctccagagtg tgaagctgca ggaaggttct tcagaagacc   1140

tgaaattctg cgtgctctat ctagcagaga aggcagagtg cttattcact ttggaagcgc   1200

actcgcagga gcagaagaag agagtgtgct ggtgcctgtc ggagaacatc gccaagcagc   1260

aacagctggc agcatcaccc ccggacagca agatgagcgg ggctgacacc gttggggatg   1320

atgacgaagc ctcccggaag agaaagagca aaaacctagc caaggacatg aagaacaagc   1380

tggggatctt cagacggcgg aatgagtccc ctggagcccc tcccgcgggc aaggcagaca   1440

aaatgatgaa gtcattcaag cccacctcag aggaagccct caagtggggc gagtccttgg   1500

agaagctgct ggttcacaaa tacgggttag cagtgttcca agccttcctt cgcactgagt   1560

tcagtgagga gaatctggag ttctggttgg cttgtgagga cttcaagaag gtcaagtcac   1620

agtccaagat ggcatccaag gccaagaaga tctttgctga atacatcgcg atccaggcat   1680

gcaaggaggt caacctggac tcctacacgc gggagcacac caaggacaac ctgcagagcg   1740

tcacgcgggg ctgcttcgac ctggcacaga agcgcatctt cgggctcatg gaaaaggact   1800

cgtaccctcg ctttctccgt tctgacctct acctggacct tattaaccag aagaagatga   1860

gtcccccgct ttaggggcca ctggagtcga gctcagcgtt cacaccaggc gggctgggtc   1920

ccctgcccac ctgcctccct gccccctgtg acggaggggg caagcaagcc cccagaggct   1980

gtgtctctgg acagacggat agacatacgg aagcgaggcc tggaccaaga gaggcccagg   2040

ctactggagg agtagaagga tgggccccgt ggggtcccca ctgccccggt acgagggggc   2100

ccaagaccct ggcaggtcag gggccctggc caagccagat ctggagctgc tgctccctgc   2160

tgcggagacc gcggaggctt cgcgttgacc aagttcctta aagaactggc tgatggggca   2220

ggaggtccag gcctgggctc tcgggccctc ctagagggcc attggagctt gcagctcaga   2280

cccccacttt gagttttatt tatttaaata gtagttggat gcttggcacg tcgtcctgta   2340

ataggaaacc cttgcctcat cagttttcct gatttacaag tgcaatattt tagccaatgc   2400

cttgggagaa gctgccatgc aaaggtggac accattctcc agcttcaggg gatatgctcg   2460

tcccgggcac cggtggcagg cagctggcct tctggactaa ggcagcctgg ggggacactg   2520

cagtctggct acacacagag atctggcacc ccctgggtgg agtgtccctc gggggctttg   2580

ggaaagcatg gcaccctcag accacacagt agccaagttc tggagcaaat aaaaggcctg   2640

tgttatttct tgttcttgac cctt                                          2664


<210>  6265
<211>  591
<212>  PRT
<213>  Homo sapiens

<400>  6265

Met Asn Arg Phe Asn Gly Leu Cys Lys Val Cys Ser Glu Arg Arg Tyr 
1               5                   10                  15


Arg Gln Ile Thr Ile Pro Arg Gly Lys Asp Gly Phe Gly Phe Thr Ile 
            20                  25                  30


Cys Cys Asp Ser Pro Val Arg Val Gln Ala Val Asp Ser Gly Gly Pro 
        35                  40                  45


Ala Glu Arg Ala Gly Leu Gln Gln Leu Asp Thr Val Leu Gln Leu Asn 
    50                  55                  60


Glu Arg Pro Val Glu His Trp Lys Cys Val Glu Leu Ala His Glu Ile 
65                  70                  75                  80


Arg Ser Cys Pro Ser Glu Ile Ile Leu Leu Val Trp Arg Met Val Pro 
                85                  90                  95


Gln Val Lys Pro Gly Pro Asp Gly Gly Val Leu Arg Arg Ala Ser Cys 
            100                 105                 110


Lys Ser Thr His Asp Leu Gln Ser Pro Pro Asn Lys Arg Glu Lys Asn 
        115                 120                 125


Cys Thr His Gly Val Gln Ala Arg Pro Glu Gln Arg His Ser Cys His 
    130                 135                 140


Leu Val Cys Asp Ser Ser Asp Gly Leu Leu Leu Gly Gly Trp Glu Arg 
145                 150                 155                 160


Tyr Thr Glu Val Ala Lys Arg Gly Gly Gln His Thr Leu Pro Ala Leu 
                165                 170                 175


Ser Arg Ala Thr Ala Pro Thr Asp Pro Asn Tyr Ile Ile Leu Ala Pro 
            180                 185                 190


Leu Asn Pro Gly Ser Gln Leu Leu Arg Pro Val Tyr Gln Glu Asp Thr 
        195                 200                 205


Ile Pro Glu Glu Ser Gly Ser Pro Ser Lys Gly Lys Ser Tyr Thr Gly 
    210                 215                 220


Leu Gly Lys Lys Ser Arg Leu Met Lys Thr Val Gln Thr Met Lys Gly 
225                 230                 235                 240


His Gly Asn Tyr Gln Asn Cys Pro Val Val Arg Pro His Ala Thr His 
                245                 250                 255


Ser Ser Tyr Gly Thr Tyr Val Thr Leu Ala Pro Lys Val Leu Val Phe 
            260                 265                 270


Pro Val Phe Val Gln Pro Leu Asp Leu Cys Asn Pro Ala Arg Thr Leu 
        275                 280                 285


Leu Leu Ser Glu Glu Leu Leu Leu Tyr Glu Gly Arg Asn Lys Ala Ala 
    290                 295                 300


Glu Val Thr Leu Phe Ala Tyr Ser Asp Leu Leu Leu Phe Thr Lys Glu 
305                 310                 315                 320


Asp Glu Pro Gly Arg Cys Asp Val Leu Arg Asn Pro Leu Tyr Leu Gln 
                325                 330                 335


Ser Val Lys Leu Gln Glu Gly Ser Ser Glu Asp Leu Lys Phe Cys Val 
            340                 345                 350


Leu Tyr Leu Ala Glu Lys Ala Glu Cys Leu Phe Thr Leu Glu Ala His 
        355                 360                 365


Ser Gln Glu Gln Lys Lys Arg Val Cys Trp Cys Leu Ser Glu Asn Ile 
    370                 375                 380


Ala Lys Gln Gln Gln Leu Ala Ala Ser Pro Pro Asp Ser Lys Met Ser 
385                 390                 395                 400


Gly Ala Asp Thr Val Gly Asp Asp Asp Glu Ala Ser Arg Lys Arg Lys 
                405                 410                 415


Ser Lys Asn Leu Ala Lys Asp Met Lys Asn Lys Leu Gly Ile Phe Arg 
            420                 425                 430


Arg Arg Asn Glu Ser Pro Gly Ala Pro Pro Ala Gly Lys Ala Asp Lys 
        435                 440                 445


Met Met Lys Ser Phe Lys Pro Thr Ser Glu Glu Ala Leu Lys Trp Gly 
    450                 455                 460


Glu Ser Leu Glu Lys Leu Leu Val His Lys Tyr Gly Leu Ala Val Phe 
465                 470                 475                 480


Gln Ala Phe Leu Arg Thr Glu Phe Ser Glu Glu Asn Leu Glu Phe Trp 
                485                 490                 495


Leu Ala Cys Glu Asp Phe Lys Lys Val Lys Ser Gln Ser Lys Met Ala 
            500                 505                 510


Ser Lys Ala Lys Lys Ile Phe Ala Glu Tyr Ile Ala Ile Gln Ala Cys 
        515                 520                 525


Lys Glu Val Asn Leu Asp Ser Tyr Thr Arg Glu His Thr Lys Asp Asn 
    530                 535                 540


Leu Gln Ser Val Thr Arg Gly Cys Phe Asp Leu Ala Gln Lys Arg Ile 
545                 550                 555                 560


Phe Gly Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Arg Ser Asp 
                565                 570                 575


Leu Tyr Leu Asp Leu Ile Asn Gln Lys Lys Met Ser Pro Pro Leu 
            580                 585                 590


<210>  6266
<211>  677
<212>  DNA
<213>  Homo sapiens

<400>  6266
aatgtggtca gtgatcatgg tggacagagt gtaattctgc ttcctccgag ctaggagcac     60

agggcccgcc ccaggctaac gctctgtgaa cctctgtgag aaaggaagaa gggagccagg    120

aaaacagtgg atcaaagatc accatcccga ggggaaagga cggctttggc ttcaccatct    180

gctgcgactc tccagttcga gtccaggccg tggattccgg gggtccggcg gaacgggcag    240

ggctgcagca gctggacacg gtgctgcagc tgaatgagag gcctgtggag cactggaaat    300

gtgtggagct ggcccacgag atccggagct gccccagtga gatcatccta ctcgtgtggc    360

gcatggtccc ccaggtcaag ccaggaccag atggcggggt cctgcggcgg gcctcctgca    420

agtcgacaca tgacctccag tcacccccca acaaacggga gaagaactgc acccatgggg    480

tccaggcacg gcctgagcag cgccacagct gccacctggt atgtgacagc tctgatgggc    540

tgctgctcgg cggctgggag cgctacaccg aggtggccaa gcgcgggggc cagcacaccc    600

tgcctgcact gtcccgtgcc actgccccca ccgaccccaa ctacatcatc ctggccccgc    660

tgaatcctgg gagccag                                                   677


<210>  6267
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  6267

Met Arg Gly Leu Trp Ser Thr Gly Asn Val Trp Ser Trp Pro Thr Arg 
1               5                   10                  15


Ser Gly Ala Ala Pro Val Arg Ser Ser Tyr Ser Cys Gly Ala Trp Ser 
            20                  25                  30


Pro Arg Ser Ser Gln Asp Gln Met Ala Gly Ser Cys Gly Gly Pro Pro 
        35                  40                  45


Ala Ser Arg His Met Thr Ser Ser His Pro Pro Thr Asn Gly Arg Arg 
    50                  55                  60


Thr Ala Pro Met Gly Ser Arg His Gly Leu Ser Ser Ala Thr Ala Ala 
65                  70                  75                  80


Thr Trp Tyr Val Thr Ala Leu Met Gly Cys Cys Ser Ala Ala Gly Ser 
                85                  90                  95


Ala Thr Pro Arg Trp Pro Ser Ala Gly Ala Ser Thr Pro Cys Leu His 
            100                 105                 110


Cys Pro Val Pro Leu Pro Pro Pro Thr Pro Thr Thr Ser Ser Trp Pro 
        115                 120                 125


Arg 



<210>  6268
<211>  2090
<212>  DNA
<213>  Homo sapiens

<400>  6268
agtgctcaag ttgtctgggc tgagataggg acactgaggg gctggctagc tcctttgtgc     60

ctccagttcc cttggagagg agggtggctc ttggcagggg tgggctgtgg gcttcctgac    120

cttggggtag aggcaagagc ctccagcttc tggcagtgac cgggcagggc tgtgtcctag    180

atcaccatcc cgaggggaaa ggacggcttt ggcttcacca tctgctgcga ctctccagtt    240

cgagtccagg ccgtggattc cgggggtccg gcggaacggg cagggctgca gcagctggac    300

acggtgctgc agctgaatga gaggcctgtg gagcactgga aatgtgtgga gctggcccac    360

gagatccgga gctgccccag tgagatcatc ctactcgtgt ggcgcatggt cccccaggtc    420

aagccaggac cagatggcgg ggtcctgcgg cgggcctcct gcaagtcgac acatgacctc    480

cagtcacccc ccaacaaacg ggagaagaac tgcacccatg gggtccaggc acggcctgag    540

cagcgccaca gctgccacct ggtatgtgac agctctgatg ggctgctgct cggcggctgg    600

gagcgctaca ccgaggtggc caagcgcggg ggccagcaca ccctgcctgc actgtcccgt    660

gccactgccc ccaccgaccc caactacatc atcctggccc cgctgaatcc tgggagccag    720

ctgctccggc ctgtgtacca ggaggatacc atccccgaag aatcagggag tcccagtaaa    780

gggaagtcct acacaggcct ggggaagaag tcccggctga tgaagacagt gcagaccatg    840

aagggccacg ggaactacca aaactgcccg gttgtgaggc cgcatgccac gcactcaagc    900

tatggcacct acgtcaccct ggcccccaaa gtcctggtgt tccctgtctt tgttcagcct    960

ctagatctct gtaatcctgc ccggaccctc ctgctgtcag aggagctgct gctgtatgaa   1020

gggaggaaca aggctgccga ggtgacactg tttgcctatt cggacctgct gctcttcacc   1080

aaggaggacg agcctggccg ctgcgacgtc ctgaggaacc ccctctacct ccagagtgtg   1140

aagctgcagg aaggttcttc agaagacctg aaattctgcg tgctctatct agcagagaag   1200

gcagagtgct tattcacttt ggaagcgcac tcgcaggagc agaagaagag agtgtgctgg   1260

tgcctgtcgg agaacatcgc caagcagcaa cagctggcag catcaccccc ggacagcaag   1320

aaactccacc ctttcggctc tctccagcag gagatggggc cggtcaactc aaccaatgcc   1380

acccaggata gaagctttac ctcaccagga cagactctga ttggctgagc aaacccaagg   1440

gcgggactct gcttctggca acttaaccct ttcttgggca tcccctacca cacagtaacc   1500

tcacctcaac tggacctgaa acagaggacc aagatggtgg gtctagggtc atctgaaggg   1560

agtggtccca agggtgcatg tggatgtcaa cagaaggacc acaatggtgt gagaggcctt   1620

gtgggcatgc agagactggc agcagaaagt cccaagagga gaggactcag aggcttcttc   1680

cttccaagga ggaggaggag gaggacattc cacatctggg cttccagtgg tggctcccgg   1740

acctgccttg ggggcagcag gagaggttgg gagaggtcac cctgatgaag aacaatgcca   1800

tgatctgctg ctgccagagg acatctccgc ccatccactc attttccacc tgtacacatt   1860

ggctcattca ttcgatggat atttcgggtg catctacttt atgccaggct ctatgctagg   1920

agctggggat actgtggaga aaaagtcgga tatggtctcg ctctcatcaa gatttcagtc   1980

tagctgggag tgagcgttaa ataagtcaat accaacacac acacgtgcac acacgtgatg   2040

gcaagctgtg atcatctatg aaagaaaaaa cacagatttc tttaagaggg              2090


<210>  6269
<211>  340
<212>  PRT
<213>  Homo sapiens

<400>  6269

Met Val Pro Gln Val Lys Pro Gly Pro Asp Gly Gly Val Leu Arg Arg 
1               5                   10                  15


Ala Ser Cys Lys Ser Thr His Asp Leu Gln Ser Pro Pro Asn Lys Arg 
            20                  25                  30


Glu Lys Asn Cys Thr His Gly Val Gln Ala Arg Pro Glu Gln Arg His 
        35                  40                  45


Ser Cys His Leu Val Cys Asp Ser Ser Asp Gly Leu Leu Leu Gly Gly 
    50                  55                  60


Trp Glu Arg Tyr Thr Glu Val Ala Lys Arg Gly Gly Gln His Thr Leu 
65                  70                  75                  80


Pro Ala Leu Ser Arg Ala Thr Ala Pro Thr Asp Pro Asn Tyr Ile Ile 
                85                  90                  95


Leu Ala Pro Leu Asn Pro Gly Ser Gln Leu Leu Arg Pro Val Tyr Gln 
            100                 105                 110


Glu Asp Thr Ile Pro Glu Glu Ser Gly Ser Pro Ser Lys Gly Lys Ser 
        115                 120                 125


Tyr Thr Gly Leu Gly Lys Lys Ser Arg Leu Met Lys Thr Val Gln Thr 
    130                 135                 140


Met Lys Gly His Gly Asn Tyr Gln Asn Cys Pro Val Val Arg Pro His 
145                 150                 155                 160


Ala Thr His Ser Ser Tyr Gly Thr Tyr Val Thr Leu Ala Pro Lys Val 
                165                 170                 175


Leu Val Phe Pro Val Phe Val Gln Pro Leu Asp Leu Cys Asn Pro Ala 
            180                 185                 190


Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu Leu Tyr Glu Gly Arg Asn 
        195                 200                 205


Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr Ser Asp Leu Leu Leu Phe 
    210                 215                 220


Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp Val Leu Arg Asn Pro Leu 
225                 230                 235                 240


Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly Ser Ser Glu Asp Leu Lys 
                245                 250                 255


Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala Glu Cys Leu Phe Thr Leu 
            260                 265                 270


Glu Ala His Ser Gln Glu Gln Lys Lys Arg Val Cys Trp Cys Leu Ser 
        275                 280                 285


Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala Ala Ser Pro Pro Asp Ser 
    290                 295                 300


Lys Lys Leu His Pro Phe Gly Ser Leu Gln Gln Glu Met Gly Pro Val 
305                 310                 315                 320


Asn Ser Thr Asn Ala Thr Gln Asp Arg Ser Phe Thr Ser Pro Gly Gln 
                325                 330                 335


Thr Leu Ile Gly 
            340


<210>  6270
<211>  1101
<212>  DNA
<213>  Homo sapiens

<400>  6270
cccttgcagc tgctccggcc tgtgtaccag gaggatacca tccccgaagc ctctagatct     60

ctgtaatcct gcccggaccc tcctgctgtc agaggagctg ctgctgtatg aagggaggaa    120

caaggctgcc gaggtgacac tgtttgccta ttcggacctg ctgctcttca ccaaggagga    180

cgagcctggc cgctgcgacg tcctgaggaa ccccctctac ctccagagtg tgaagctgca    240

ggaaggttct tcagaagacc tgaaattctg cgtgctctat ctagcagaga aggcagagtg    300

cttattcact ttggaagcgc actcgcagga cttcctccag gacaagacct tccacccaac    360

aaggactccc cttctgggca ggaacccgct cccagccaag aaccactgtc cagcaaagac    420

tcagctacct ctgaaggatc ccctccaggc ccagatgctc cgcccagcaa ggatgtgcca    480

ccatgccagg aaccccctcc agcccaagac ctctcaccct gccaggacct acctgctggt    540

caagaacccc tgcctcacca ggaccctcta ctcaccaaag acctccctgc catccaggaa    600

tcccccaccc gggaccttcc accctgtcaa gatctgcctc ctagccaggt ctccctgcca    660

gccaaggccc ttactgagga caccatgagc tccggggacc tactagcagc tactggggac    720

ccacctgcgg cccccaggcc agccttcgtg atccctgagg tccggctgga tagcacctac    780

agccagaagg caggggcaga gcagggctgc tcgggagatg aggaggatgc agaagaggcc    840

gaggaggtgg aggaggggga ggaaggggag gaggacgagg atgaggacac cagcgatgac    900

aactacggag agcgcagtga ggccaagcgc agcagcatga tcgagacggg ccagggggct    960

gagggtggcc tctcactgcg tgtgcagaac tcgctgcggc gccggacgca cagcgagggc   1020

agcctgctgc aggagccccg agggccctgc tttgcctccg acaccacctt gcactgctca   1080

gacggtgagg gcgccgcctc c                                             1101


<210>  6271
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  6271

Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala 
1               5                   10                  15


Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr 
            20                  25                  30


Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp 
        35                  40                  45


Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu Asp 
    50                  55                  60


Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala 
65                  70                  75                  80


Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu 
                85                  90                  95


Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu Gly 
            100                 105                 110


Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr 
        115                 120                 125


Leu His Cys Ser Asp Gly Glu Gly Ala Ala 
    130                 135


<210>  6272
<211>  1399
<212>  DNA
<213>  Homo sapiens

<400>  6272
ggggaagaag tcccggctga tgaagacagt gcagaccatg aagggccacg ggaactacca     60

aaactgcccg gttgtgaggc cgcatgccac gcactcaagc tatggcacct acgtcaccct    120

ggcccccaaa gtcctggtgt tccctgtctt tgttcagcct ctagatctct gtaatcctgc    180

ccggaccctc ctgctgtcag aggagctgct gctgtatgaa gggaggaaca aggctgccga    240

ggtgacactg tttgcctatt cggacctgct gctcttcacc aaggaggacg agcctggccg    300

ctgcgacgtc ctgaggaacc ccctctacct ccagagtgtg aagctgcagg aaggttcttc    360

agaagacctg aaattctgcg tgctctatct agcagagaag gcagagtgct tattcacttt    420

ggaagcgcac tcgcaggagc agaagaagag agtgtgctgg tgcctgtcgg agaacatcgc    480

caagcagcaa cagctggcag catcaccccc ggacagcaag atgtttgaga cggaggcaga    540

tgagaagagg gagatggcct tggaggaagg gaaggggcct ggtgccgagg attccccacc    600

cagcaaggag ccctctcctg gccaggagct tcctccagga caagaccttc cacccaacaa    660

ggactcccct tctgggcagg aacccgctcc cagccaagaa ccactgtcca gcaaagactc    720

agctacctct gaaggatccc ctccaggccc agatgctccg cccagcaagg atgtgccacc    780

atgccaggaa ccccctccag cccaagacct ctcaccctgc caggacctac ctgctggtca    840

agaacccctg cctcaccagg accctctact caccaaagac ctccctgcca tccaggaatc    900

ccccacccgg gaccttccac cctgtcaaga tctgcctcct agccaggtct ccctgccagc    960

caaggccctt actgaggaca ccatgagctc cggggaccta ctagcagcta ctggggaccc   1020

acctgcggcc cccaggccag ccttcgtgat ccctgaggtc cggctggata gcacctacag   1080

ccagaaggca ggggcagagc agggctgctc gggagatgag gaggatgcag aagaggccga   1140

ggaggtggag gagggggagg aaggggagga ggacgaggat gaggacacca gcgatgacaa   1200

ctacggagag cgcagtgagg ccaagcgcag cagcatgatc gagacgggcc agggggctga   1260

gggtggcctc tcactgcgtg tgcagaactc gctgcggcgc cggacgcaca gcgagggcag   1320

cctgctgcag gagccccgag ggccctgctt tgcctccgac accaccttgc actgctcaga   1380

cggtgagggc gccgcctcc                                                1399


<210>  6273
<211>  459
<212>  PRT
<213>  Homo sapiens

<400>  6273

Met Lys Thr Val Gln Thr Met Lys Gly His Gly Asn Tyr Gln Asn Cys 
1               5                   10                  15


Pro Val Val Arg Pro His Ala Thr His Ser Ser Tyr Gly Thr Tyr Val 
            20                  25                  30


Thr Leu Ala Pro Lys Val Leu Val Phe Pro Val Phe Val Gln Pro Leu 
        35                  40                  45


Asp Leu Cys Asn Pro Ala Arg Thr Leu Leu Leu Ser Glu Glu Leu Leu 
    50                  55                  60


Leu Tyr Glu Gly Arg Asn Lys Ala Ala Glu Val Thr Leu Phe Ala Tyr 
65                  70                  75                  80


Ser Asp Leu Leu Leu Phe Thr Lys Glu Asp Glu Pro Gly Arg Cys Asp 
                85                  90                  95


Val Leu Arg Asn Pro Leu Tyr Leu Gln Ser Val Lys Leu Gln Glu Gly 
            100                 105                 110


Ser Ser Glu Asp Leu Lys Phe Cys Val Leu Tyr Leu Ala Glu Lys Ala 
        115                 120                 125


Glu Cys Leu Phe Thr Leu Glu Ala His Ser Gln Glu Gln Lys Lys Arg 
    130                 135                 140


Val Cys Trp Cys Leu Ser Glu Asn Ile Ala Lys Gln Gln Gln Leu Ala 
145                 150                 155                 160


Ala Ser Pro Pro Asp Ser Lys Met Phe Glu Thr Glu Ala Asp Glu Lys 
                165                 170                 175


Arg Glu Met Ala Leu Glu Glu Gly Lys Gly Pro Gly Ala Glu Asp Ser 
            180                 185                 190


Pro Pro Ser Lys Glu Pro Ser Pro Gly Gln Glu Leu Pro Pro Gly Gln 
        195                 200                 205


Asp Leu Pro Pro Asn Lys Asp Ser Pro Ser Gly Gln Glu Pro Ala Pro 
    210                 215                 220


Ser Gln Glu Pro Leu Ser Ser Lys Asp Ser Ala Thr Ser Glu Gly Ser 
225                 230                 235                 240


Pro Pro Gly Pro Asp Ala Pro Pro Ser Lys Asp Val Pro Pro Cys Gln 
                245                 250                 255


Glu Pro Pro Pro Ala Gln Asp Leu Ser Pro Cys Gln Asp Leu Pro Ala 
            260                 265                 270


Gly Gln Glu Pro Leu Pro His Gln Asp Pro Leu Leu Thr Lys Asp Leu 
        275                 280                 285


Pro Ala Ile Gln Glu Ser Pro Thr Arg Asp Leu Pro Pro Cys Gln Asp 
    290                 295                 300


Leu Pro Pro Ser Gln Val Ser Leu Pro Ala Lys Ala Leu Thr Glu Asp 
305                 310                 315                 320


Thr Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala 
                325                 330                 335


Ala Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr 
            340                 345                 350


Tyr Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu 
        355                 360                 365


Asp Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu 
    370                 375                 380


Asp Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu 
385                 390                 395                 400


Ala Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly 
                405                 410                 415


Leu Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu 
            420                 425                 430


Gly Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr 
        435                 440                 445


Thr Leu His Cys Ser Asp Gly Glu Gly Ala Ala 
    450                 455


<210>  6274
<211>  1279
<212>  DNA
<213>  Homo sapiens

<400>  6274
gtggttagac ttcctgtcaa tgagtgtagc tctcacgcct ctagatctct gtaatcctgc     60

ccggaccctc ctgctgtcag aggagctgct gctgtatgaa gggaggaaca aggctgccga    120

ggtgacactg tttgcctatt cggacctgct gctcttcacc aaggaggacg agcctggccg    180

ctgcgacgtc ctgaggaacc ccctctacct ccagagtgtg aagctgcagg aaggttcttc    240

agaagacctg aaattctgcg tgctctatct agcagagaag gcagagtgct tattcacttt    300

ggaagcgcac tcgcaggagc agaagaagag agtgtgctgg tgcctgtcgg agaacatcgc    360

caagcagcaa cagctggcag catcaccccc ggacagcaag atgtttgaga cggaggcaga    420

tgagaagagg gagatggcct tggaggaagg gaaggggcct ggtgccgagg attccccacc    480

cagcaaggag ccctctcctg gccaggagct tcctccagga caagaccttc cacccaacaa    540

ggactcccct tctgggcagg aacccgctcc cagccaagaa ccactgtcca gcaaagactc    600

agctacctct gaaggatccc ctccaggccc agatgctccg cccagcaagg atgtgccacc    660

atgccaggaa ccccctccag cccaagacct ctcaccctgc caggacctac ctgctggtca    720

agaacccctg cctcaccagg accctctact caccaaagac ctccctgcca tccaggaatc    780

ccccacccgg gaccttccac cctgtcaaga tctgcctcct agccaggtct ccctgccagc    840

caaggccctt actgaggaca ccatgagctc cggggaccta ctagcagcta ctggggaccc    900

acctgcggcc cccaggccag ccttcgtgat ccctgaggtc cggctggata gcacctacag    960

ccagaaggca ggggcagagc agggctgctc gggagatgag gaggatgcag aagaggccga   1020

ggaggtggag gagggggagg aaggggagga ggacgaggat gaggacacca gcgatgacaa   1080

ctacggagag cgcagtgagg ccaagcgcag cagcatgatc gagacgggcc agggggctga   1140

gggtggcctc tcactgcgtg tgcagaactc gctgcggcgc cggacgcaca gcgagggcag   1200

cctgctgcag gagccccgag ggccctgctt tgcctccgac accaccttgc actgctcaga   1260

cggtgagggc gccgcctcc                                                1279


<210>  6275
<211>  419
<212>  PRT
<213>  Homo sapiens

<400>  6275

Met Ser Val Ala Leu Thr Pro Leu Asp Leu Cys Asn Pro Ala Arg Thr 
1               5                   10                  15


Leu Leu Leu Ser Glu Glu Leu Leu Leu Tyr Glu Gly Arg Asn Lys Ala 
            20                  25                  30


Ala Glu Val Thr Leu Phe Ala Tyr Ser Asp Leu Leu Leu Phe Thr Lys 
        35                  40                  45


Glu Asp Glu Pro Gly Arg Cys Asp Val Leu Arg Asn Pro Leu Tyr Leu 
    50                  55                  60


Gln Ser Val Lys Leu Gln Glu Gly Ser Ser Glu Asp Leu Lys Phe Cys 
65                  70                  75                  80


Val Leu Tyr Leu Ala Glu Lys Ala Glu Cys Leu Phe Thr Leu Glu Ala 
                85                  90                  95


His Ser Gln Glu Gln Lys Lys Arg Val Cys Trp Cys Leu Ser Glu Asn 
            100                 105                 110


Ile Ala Lys Gln Gln Gln Leu Ala Ala Ser Pro Pro Asp Ser Lys Met 
        115                 120                 125


Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu Gly 
    130                 135                 140


Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser Pro 
145                 150                 155                 160


Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp Ser 
                165                 170                 175


Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser Lys 
            180                 185                 190


Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro Pro 
        195                 200                 205


Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp Leu 
    210                 215                 220


Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His Gln 
225                 230                 235                 240


Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro Thr 
                245                 250                 255


Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser Leu 
            260                 265                 270


Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu Leu 
        275                 280                 285


Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val Ile 
    290                 295                 300


Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala Glu 
305                 310                 315                 320


Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu Val 
                325                 330                 335


Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser Asp 
            340                 345                 350


Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile Glu 
        355                 360                 365


Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn Ser 
    370                 375                 380


Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro Arg 
385                 390                 395                 400


Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly Glu 
                405                 410                 415


Gly Ala Ala 



<210>  6276
<211>  1243
<212>  DNA
<213>  Homo sapiens

<400>  6276
aaacttatcc acaaggaatt tgataatatt agctcacatt gtgtggcgct ttactaggtc     60

tgcaaaaagc tcttggaagg atcctgtgac actgtttgcc tattcggacc tgctgctctt    120

caccaaggag gacgagcctg gccgctgcga cgtcctgagg aaccccctct acctccagag    180

tgtgaagctg caggaaggtt cttcagaaga cctgaaattc tgcgtgctct atctagcaga    240

gaaggcagag tgcttattca ctttggaagc gcactcgcag gagcagaaga agagagtgtg    300

ctggtgcctg tcggagaaca tcgccaagca gcaacagctg gcagcatcac ccccggacag    360

caagatgttt gagacggagg cagatgagaa gagggagatg gccttggagg aagggaaggg    420

gcctggtgcc gaggattccc cacccagcaa ggagccctct cctggccagg agcttcctcc    480

aggacaagac cttccaccca acaaggactc cccttctggg caggaacccg ctcccagcca    540

agaaccactg tccagcaaag actcagctac ctctgaagga tcccctccag gcccagatgc    600

tccgcccagc aaggatgtgc caccatgcca ggaaccccct ccagcccaag acctctcacc    660

ctgccaggac ctacctgctg gtcaagaacc cctgcctcac caggaccctc tactcaccaa    720

agacctccct gccatccagg aatcccccac ccgggacctt ccaccctgtc aagatctgcc    780

tcctagccag gtctccctgc cagccaaggc ccttactgag gacaccatga gctccgggga    840

cctactagca gctactgggg acccacctgc ggcccccagg ccagccttcg tgatccctga    900

ggtccggctg gatagcacct acagccagaa ggcaggggca gagcagggct gctcgggaga    960

tgaggaggat gcagaagagg ccgaggaggt ggaggagggg gaggaagggg aggaggacga   1020

ggatgaggac accagcgatg acaactacgg agagcgcagt gaggccaagc gcagcagcat   1080

gatcgagacg ggccaggggg ctgagggtgg cctctcactg cgtgtgcaga actcgctgcg   1140

gcgccggacg cacagcgagg gcagcctgct gcaggagccc cgagggccct gctttgcctc   1200

cgacaccacc ttgcactgct cagacggtga gggcgccgcc tcc                     1243


<210>  6277
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6277

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6278
<211>  1336
<212>  DNA
<213>  Homo sapiens

<400>  6278
agtgctcttt cagccagaca cttagagcag aataaaagca aatatggaaa atcttacagc     60

ttaaggattg ctccaagccc caggtgctgg gctggaggct ccaggagcat ttggtcagag    120

atgtaggctt cggggatcag gctgtggaga ggcttgcaga gaccagctgc catggagggt    180

gacactgttt gcctattcgg acctgctgct cttcaccaag gaggacgagc ctggccgctg    240

cgacgtcctg aggaaccccc tctacctcca gagtgtgaag ctgcaggaag gttcttcaga    300

agacctgaaa ttctgcgtgc tctatctagc agagaaggca gagtgcttat tcactttgga    360

agcgcactcg caggagcaga agaagagagt gtgctggtgc ctgtcggaga acatcgccaa    420

gcagcaacag ctggcagcat cacccccgga cagcaagatg tttgagacgg aggcagatga    480

gaagagggag atggccttgg aggaagggaa ggggcctggt gccgaggatt ccccacccag    540

caaggagccc tctcctggcc aggagcttcc tccaggacaa gaccttccac ccaacaagga    600

ctccccttct gggcaggaac ccgctcccag ccaagaacca ctgtccagca aagactcagc    660

tacctctgaa ggatcccctc caggcccaga tgctccgccc agcaaggatg tgccaccatg    720

ccaggaaccc cctccagccc aagacctctc accctgccag gacctacctg ctggtcaaga    780

acccctgcct caccaggacc ctctactcac caaagacctc cctgccatcc aggaatcccc    840

cacccgggac cttccaccct gtcaagatct gcctcctagc caggtctccc tgccagccaa    900

ggcccttact gaggacacca tgagctccgg ggacctacta gcagctactg gggacccacc    960

tgcggccccc aggccagcct tcgtgatccc tgaggtccgg ctggatagca cctacagcca   1020

gaaggcaggg gcagagcagg gctgctcggg agatgaggag gatgcagaag aggccgagga   1080

ggtggaggag ggggaggaag gggaggagga cgaggatgag gacaccagcg atgacaacta   1140

cggagagcgc agtgaggcca agcgcagcag catgatcgag acgggccagg gggctgaggg   1200

tggcctctca ctgcgtgtgc agaactcgct gcggcgccgg acgcacagcg agggcagcct   1260

gctgcaggag ccccgagggc cctgctttgc ctccgacacc accttgcact gctcagacgg   1320

tgagggcgcc gcctcc                                                   1336


<210>  6279
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6279

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6280
<211>  1321
<212>  DNA
<213>  Homo sapiens

<400>  6280
gtgctgcctg cccctggggg tgacctcatc ggctctgtcc tgctctccac aggcctctgc     60

tgtgttggga gccactgcct tcctcccctc ccccaacctg tgggcccaca gctcgccagc    120

tggcccttga acccacttcc ctgcgcctct ggctgcctca atgtcactgg ggattagtgt    180

gcatttgcgg cttttggcgg acactcccct cctggctgca gcctcaccct ctggagccca    240

gggatgggct tgggcctggg agccccctga accagggagc agccctgacc gtccgtttct    300

ctattttccc tgacgtcaga aggcagagtg cttattcact ttggaagcgc actcgcagga    360

gcagaagaag agagtgtgct ggtgcctgtc ggagaacatc gccaagcagc aacagctggc    420

agcatcaccc ccggacagca agatgtttga gacggaggca gatgagaaga gggagatggc    480

cttggaggaa gggaaggggc ctggtgccga ggattcccca cccagcaagg agccctctcc    540

tggccaggag cttcctccag gacaagacct tccacccaac aaggactccc cttctgggca    600

ggaacccgct cccagccaag aaccactgtc cagcaaagac tcagctacct ctgaaggatc    660

ccctccaggc ccagatgctc cgcccagcaa ggatgtgcca ccatgccagg aaccccctcc    720

agcccaagac ctctcaccct gccaggacct acctgctggt caagaacccc tgcctcacca    780

ggaccctcta ctcaccaaag acctccctgc catccaggaa tcccccaccc gggaccttcc    840

accctgtcaa gatctgcctc ctagccaggt ctccctgcca gccaaggccc ttactgagga    900

caccatgagc tccggggacc tactagcagc tactggggac ccacctgcgg cccccaggcc    960

agccttcgtg atccctgagg tccggctgga tagcacctac agccagaagg caggggcaga   1020

gcagggctgc tcgggagatg aggaggatgc agaagaggcc gaggaggtgg aggaggggga   1080

ggaaggggag gaggacgagg atgaggacac cagcgatgac aactacggag agcgcagtga   1140

ggccaagcgc agcagcatga tcgagacggg ccagggggct gagggtggcc tctcactgcg   1200

tgtgcagaac tcgctgcggc gccggacgca cagcgagggc agcctgctgc aggagccccg   1260

agggccctgc tttgcctccg acaccacctt gcactgctca gacggtgagg gcgccgcctc   1320

c                                                                   1321


<210>  6281
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6281

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6282
<211>  1185
<212>  DNA
<213>  Homo sapiens

<400>  6282
atcggctctg tcctgctctc cacaggcctc tgctgtgttg ggagccactg ccttcctccc     60

ctcccccaac ctgtgggccc acagctcgcc agctggccct tgaacccact tccctgcgcc    120

tctggctgcc tcaatgtcac tggggattag tgtgcatttg cggcttttgg cggacactcc    180

cctcctggct gcagcctcac cctctggagc ccagggatgg gcttgggcct gggagccccc    240

tgaaccaggg agcagccctg accgtccgtt tctctatttt ccctgacgtc agaaggcaga    300

gtgcttattc actttggaag cgcactcgca ggagcagaag aagagagtgt gctggtgcct    360

gtcggagaac atcgccaagc agcaacagct ggcagcatca cccccggaca gcaagaaact    420

ccaccctttc ggctctctcc agcaggagat ggggccggtc aactcaacca atgccaccca    480

ggatagaagc tttacctcac caggacagac tctgattggc tgagcaaacc caagggcggg    540

actctgcttc tggcaactta accctttctt gggcatcccc taccacacag taacctcacc    600

tcaactggac ctgaaacaga ggaccaagat ggtgggtcta gggtcatctg aagggagtgg    660

tcccaagggt gcatgtggat gtcaacagaa ggaccacaat ggtgtgagag gccttgtggg    720

catgcagaga ctggcagcag aaagtcccaa gaggagagga ctcagaggct tcttccttcc    780

aaggaggagg aggaggagga cattccacat ctgggcttcc agtggtggct cccggacctg    840

ccttgggggc agcaggagag gttgggagag gtcaccctga tgaagaacaa tgccatgatc    900

tgctgctgcc agaggacatc tccgcccatc cactcatttt ccacctgtac acattggctc    960

attcattcga tggatatttc gggtgcatct actttatgcc aggctctatg ctaggagctg   1020

gggatactgt ggagaaaaag tcggatatgg tctcgctctc atcaagattt cagtctagct   1080

gggagtgagc gttaaataag tcaataccaa cacacacacg tgcacacacg tgatggcaag   1140

ctgtgatcat ctatgaaaga aaaaacacag atttctttaa gaggg                   1185


<210>  6283
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  6283

Met Trp Met Ser Thr Glu Gly Pro Gln Trp Cys Glu Arg Pro Cys Gly 
1               5                   10                  15


His Ala Glu Thr Gly Ser Arg Lys Ser Gln Glu Glu Arg Thr Gln Arg 
            20                  25                  30


Leu Leu Pro Ser Lys Glu Glu Glu Glu Glu Asp Ile Pro His Leu Gly 
        35                  40                  45


Phe Gln Trp Trp Leu Pro Asp Leu Pro Trp Gly Gln Gln Glu Arg Leu 
    50                  55                  60


Gly Glu Val Thr Leu Met Lys Asn Asn Ala Met Ile Cys Cys Cys Gln 
65                  70                  75                  80


Arg Thr Ser Pro Pro Ile His Ser Phe Ser Thr Cys Thr His Trp Leu 
                85                  90                  95


Ile His Ser Met Asp Ile Ser Gly Ala Ser Thr Leu Cys Gln Ala Leu 
            100                 105                 110


Cys 



<210>  6284
<211>  1400
<212>  DNA
<213>  Homo sapiens

<400>  6284
atcggctctg tcctgctctc cacaggcctc tgctgtgttg ggagccactg ccttcctccc     60

ctcccccaac ctgtgggccc acagctcgcc agctggccct tgaacccact tccctgcgcc    120

tctggctgcc tcaatgtcac tggggattag tgtgcatttg cggcttttgg cggacactcc    180

cctcctggct gcagcctcac cctctggagc ccagggatgg gcttgggcct gggagccccc    240

tgaaccaggg agcagccctg accgtccgtt tctctatttt ccctgacgtc agaaggcaga    300

gtgcttattc actttggaag cgcactcgca ggagcagaag aagagagtgt gctggtgcct    360

gtcggagaac atcgccaagc agcaacagct ggcagcatca cccccggaca gcaagaaact    420

ccaccctttc ggctctctcc agcaggagat ggggccggtc aactcaacca atgccaccca    480

ggatagaagc tttacctcac caggacagac tctgattggc tgagcaaacc caagggcggg    540

actctgcttc tggcaactta accctttctt gggcatcccc taccacacag taacctcacc    600

tcaactggac ctgaaacaga ggaccaagat ggtgggtcta gggtcatctg aagggagtgg    660

tcccaagggt gcatgtggat gtcaacagaa ggaccacaat ggtgtgagag gccttgtggg    720

catgcagaga ctggcagcag aaagtcccaa gaggagagga ctcagaggct tcttccttcc    780

aaggaggagg aggaggagga cattccacat ctgggcttcc agtggtggct cccggacctg    840

ccttgggggc agcaggagag gttgggagag gtcaccctga tgaagaacaa tgccatgatc    900

tgctgctgcc agaggacatc tccgcccatc cactcatttt ccacctgtac acattggctc    960

attcattcga tggatatttc gggtgcatct actttatgcc aggctctatg ctaggagctg   1020

gggatactgt ggagaaaaag tcggatatgg tctcgctctc atcaagattt cagtctagct   1080

gggagtgagc gttaaataag tcaataccaa cacacacacg tgcacacacg tgatggcaag   1140

ctgtgatcat ctatgaaaga aaaaacacag atttctttaa gagggaattg tacttagagt   1200

gctgtgtgtg ggggtgggga tggggaagga cataactttt aaaccgagac ttgtgggctg   1260

gagaggaagg agccagtcct ggacttgggg aagagtgttc gcggtggatg gaatagcacg   1320

tggagagtcc ctgagatggg aaggagctca gtgggctgga ggaatggcga gcaggccagt   1380

gtggctggag cttagtgagg                                               1400


<210>  6285
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  6285

Met Trp Met Ser Thr Glu Gly Pro Gln Trp Cys Glu Arg Pro Cys Gly 
1               5                   10                  15


His Ala Glu Thr Gly Ser Arg Lys Ser Gln Glu Glu Arg Thr Gln Arg 
            20                  25                  30


Leu Leu Pro Ser Lys Glu Glu Glu Glu Glu Asp Ile Pro His Leu Gly 
        35                  40                  45


Phe Gln Trp Trp Leu Pro Asp Leu Pro Trp Gly Gln Gln Glu Arg Leu 
    50                  55                  60


Gly Glu Val Thr Leu Met Lys Asn Asn Ala Met Ile Cys Cys Cys Gln 
65                  70                  75                  80


Arg Thr Ser Pro Pro Ile His Ser Phe Ser Thr Cys Thr His Trp Leu 
                85                  90                  95


Ile His Ser Met Asp Ile Ser Gly Ala Ser Thr Leu Cys Gln Ala Leu 
            100                 105                 110


Cys 



<210>  6286
<211>  2765
<212>  DNA
<213>  Homo sapiens

<400>  6286
atcggctctg tcctgctctc cacaggcctc tgctgtgttg ggagccactg ccttcctccc     60

ctcccccaac ctgtgggccc acagctcgcc agctggccct tgaacccact tccctgcgcc    120

tctggctgcc tcaatgtcac tggggattag tgtgcatttg cggcttttgg cggacactcc    180

cctcctggct gcagcctcac cctctggagc ccagggatgg gcttgggcct gggagccccc    240

tgaaccaggg agcagccctg accgtccgtt tctctatttt ccctgacgtc agaaggcaga    300

gtgcttattc actttggaag cgcactcgca ggagcagaag aagagagtgt gctggtgcct    360

gtcggagaac atcgccaagc agcaacagct ggcagcatca cccccggaca gcaagatgtt    420

tgagacggag gcagatgaga agagggagat ggccttggag gaagggaagg ggcctggtgc    480

cgaggattcc ccacccagca aggagccctc tcctggccag gagcttcctc caggacaaga    540

ccttccaccc aacaaggact ccccttctgg gcaggaaccc gctcccagcc aagaaccact    600

gtccagcaaa gactcagcta cctctgaagg atcccctcca ggcccagatg ctccgcccag    660

caaggatgtg ccaccatgcc aggaaccccc tccagcccaa gacctctcac cctgccagga    720

cctacctgct ggtcaagaac ccctgcctca ccaggaccct ctactcacca aagacctccc    780

tgccatccag gaatccccca cccgggacct tccaccctgt caagatctgc ctcctagcca    840

ggtctccctg ccagccaagg cccttactga ggacaccatg agctccgggg acctactagc    900

agctactggg gacccacctg cggcccccag gccagccttc gtgatccctg aggtccggct    960

ggatagcacc tacagccaga aggcaggggc agagcagggc tgctcgggag atgaggagga   1020

tgcagaagag gccgaggagg tggaggaggg ggaggaaggg gaggaggacg aggatgagga   1080

caccagcgat gacaactacg gagagcgcag tgaggccaag cgcagcagca tgatcgagac   1140

gggccagggg gctgagggtg gcctctcact gcgtgtgcag aactcgctgc ggcgccggac   1200

gcacagcgag ggcagcctgc tgcaggagcc ccgagggccc tgctttgcct ccgacaccac   1260

cttgcactgc tcagacggtg agggcgccgc ctccacctgg ggcatgcctt cgcccagcac   1320

cctcaagaaa gagctgggcc gcaatggtgg ctccatgcac cacctttccc tcttcttcac   1380

aggacacagg aagatgagcg gggctgacac cgttggggat gatgacgaag cctcccggaa   1440

gagaaagagc aaaaacctag ccaaggacat gaagaacaag ctggggatct tcagacggcg   1500

gaatgagtcc cctggagccc ctcccgcggg caaggcagac aaaatgatga agtcattcaa   1560

gcccacctca gaggaagccc tcaagtgggg cgagtccttg gagaagctgc tggttcacaa   1620

atacgggtta gcagtgttcc aagccttcct tcgcactgag ttcagtgagg agaatctgga   1680

gttctggttg gcttgtgagg acttcaagaa ggtcaagtca cagtccaaga tggcatccaa   1740

ggccaagaag atctttgctg aatacatcgc gatccaggca tgcaaggagg tcaacctgga   1800

ctcctacacg cgggagcaca ccaaggacaa cctgcagagc gtcacgcggg gctgcttcga   1860

cctggcacag aagcgcatct tcgggctcat ggaaaaggac tcgtaccctc gctttctccg   1920

ttctgacctc tacctggacc ttattaacca gaagaagatg agtcccccgc tttaggggcc   1980

actggagtcg agctcagcgt tcacaccagg cgggctgggt cccctgccca cctgcctccc   2040

tgccccctgt gacggagggg gcaagcaagc ccccagaggc tgtgtctctg gacagacgga   2100

tagacatacg gaagcgaggc ctggaccaag agaggcccag gctactggag gagtagaagg   2160

atgggccccg tggggtcccc actgccccgg tacgaggggg cccaagaccc tggcaggtca   2220

ggggccctgg ccaagccaga tctggagctg ctgctccctg ctgcggagac cgcggaggct   2280

tcgcgttgac caagttcctt aaagaactgg ctgatggggc aggaggtcca ggcctgggct   2340

ctcgggccct cctagagggc cattggagct tgcagctcag acccccactt tgagttttat   2400

ttatttaaat agtagttgga tgcttggcac gtcgtcctgt aataggaaac ccttgcctca   2460

tcagttttcc tgatttacaa gtgcaatatt ttagccaatg ccttgggaga agctgccatg   2520

caaaggtgga caccattctc cagcttcagg ggatatgctc gtcccgggca ccggtggcag   2580

gcagctggcc ttctggacta aggcagcctg gggggacact gcagtctggc tacacacaga   2640

gatctggcac cccctgggtg gagtgtccct cgggggcttt gggaaagcat ggcaccctca   2700

gaccacacag tagccaagtt ctggagcaaa taaaaggcct gtgttatttc ttgttcttga   2760

ccctt                                                               2765


<210>  6287
<211>  519
<212>  PRT
<213>  Homo sapiens

<400>  6287

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr Leu Lys 
    290                 295                 300


Lys Glu Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser Leu Phe 
305                 310                 315                 320


Phe Thr Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly Asp Asp 
                325                 330                 335


Asp Glu Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Ala Lys Asp Met 
            340                 345                 350


Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly Ala 
        355                 360                 365


Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro Thr 
    370                 375                 380


Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu Val 
385                 390                 395                 400


His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu Phe 
                405                 410                 415


Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys Lys 
            420                 425                 430


Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe Ala 
        435                 440                 445


Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr 
    450                 455                 460


Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly Cys 
465                 470                 475                 480


Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp Ser 
                485                 490                 495


Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln 
            500                 505                 510


Lys Lys Met Ser Pro Pro Leu 
        515


<210>  6288
<211>  854
<212>  DNA
<213>  Homo sapiens

<400>  6288
ttccacatag gattctgcag agtttagcat tcaaagattc agctgtgtgc tgggaaggga     60

ctgaagctgc caccccccac cctgggggca gtcgcattct ggaagtcagc gtgtgctggc    120

tgcaggagcc tgggttcagt tgcagcctcc cactgggaca ggaacagcgt cggggtgggg    180

gtgtgacagg gaagcctcgg tgcctcggtg attggcttgg tcttgcaggg agcggctgcc    240

agcaggccgg ctggaggcgg ctttgcgctg ccccagcctg ggagccctca ggatgtgtgt    300

ggggtggagc ctgctaggga tcccagtgcc agggggtgcc gttgtgaggg atggacgcct    360

ctcccccgga gcagcacttt ggggccagct tgggccctgg ggatgagcca caggggaccc    420

acagcctatg cgtgtgagca tgtaacccgg gagccagctg ggcccctcgc ggggtgggca    480

gaaggacggg ctggcccagg accctcttct ttgagacatc ccggactcca tctcggatga    540

aagtgctttg agaaaccaca gagttttctg tttaatggaa gaaagaaatc cagcctctct    600

ccagagtggc ggtggccggc tagacagggc tgtggctctt acccgtgccg agctttcaca    660

tccgctcaca tctgtgctcc cagatgccag cgtgacccct gacacgtgtg tgcagcagcc    720

tgcagctgcc ccaagccatg gctgaacact gactcccagc tgtggggctt caccattaca    780

gactccccag ggcttcaaag acttctcagc ttcgagcatg gcttttggct gtcagggcag    840

ctgtacaata gtgg                                                      854


<210>  6289
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  6289

Met Glu Glu Arg Asn Pro Ala Ser Leu Gln Ser Gly Gly Gly Arg Leu 
1               5                   10                  15


Asp Arg Ala Val Ala Leu Thr Arg Ala Glu Leu Ser His Pro Leu Thr 
            20                  25                  30


Ser Val Leu Pro Asp Ala Ser Val Thr Pro Asp Thr Cys Val Gln Gln 
        35                  40                  45


Pro Ala Ala Ala Pro Ser His Gly 
    50                  55


<210>  6290
<211>  1507
<212>  DNA
<213>  Homo sapiens

<400>  6290
ttccacatag gattctgcag agtttagcat tcaaagattc agctgtgtgc tgggaaggga     60

ctgaagctgc caccccccac cctgggggca gtcgcattct ggaagtcagc gtgtgctggc    120

tgcaggagcc tgggttcagt tgcagcctcc cactgggaca ggaacagcgt cggggtgggg    180

gtgtgacagg gaagcctcgg tgcctcggtg attggcttgg tcttgcaggg agcggctgcc    240

agcaggccgg ctggaggcgg ctttgcgctg ccccagcctg ggagccctca ggatgtgtgt    300

ggggtggagc ctgctaggga tcccagtgcc agggggtgcc gttgtgaggg atggacgcct    360

ctcccccgga gcagcacttt ggggccagct tgggccctgg ggatgagcca caggggaccc    420

acagcctatg cgtgtgagca tgtaacccgg gagccagctg ggcccctcgc ggggtgggca    480

gaaggacggg ctggcccagg accctcttct ttgagacatc ccggactcca tctcggatga    540

aagtgctttg agaaaccaca gagttttctg tttaatggaa gaaagaaatc cagcctctct    600

ccagagtggc ggtggccggc tagacaggat gtttgagacg gaggcagatg agaagaggga    660

gatggccttg gaggaaggga aggggcctgg tgccgaggat tccccaccca gcaaggagcc    720

ctctcctggc caggagcttc ctccaggaca agaccttcca cccaacaagg actccccttc    780

tgggcaggaa cccgctccca gccaagaacc actgtccagc aaagactcag ctacctctga    840

aggatcccct ccaggcccag atgctccgcc cagcaaggat gtgccaccat gccaggaacc    900

ccctccagcc caagacctct caccctgcca ggacctacct gctggtcaag aacccctgcc    960

tcaccaggac cctctactca ccaaagacct ccctgccatc caggaatccc ccacccggga   1020

ccttccaccc tgtcaagatc tgcctcctag ccaggtctcc ctgccagcca aggcccttac   1080

tgaggacacc atgagctccg gggacctact agcagctact ggggacccac ctgcggcccc   1140

caggccagcc ttcgtgatcc ctgaggtccg gctggatagc acctacagcc agaaggcagg   1200

ggcagagcag ggctgctcgg gagatgagga ggatgcagaa gaggccgagg aggtggagga   1260

gggggaggaa ggggaggagg acgaggatga ggacaccagc gatgacaact acggagagcg   1320

cagtgaggcc aagcgcagca gcatgatcga gacgggccag ggggctgagg gtggcctctc   1380

actgcgtgtg cagaactcgc tgcggcgccg gacgcacagc gagggcagcc tgctgcagga   1440

gccccgaggg ccctgctttg cctccgacac caccttgcac tgctcagacg gtgagggcgc   1500

cgcctcc                                                             1507


<210>  6291
<211>  310
<212>  PRT
<213>  Homo sapiens

<400>  6291

Met Glu Glu Arg Asn Pro Ala Ser Leu Gln Ser Gly Gly Gly Arg Leu 
1               5                   10                  15


Asp Arg Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu 
            20                  25                  30


Glu Glu Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu 
        35                  40                  45


Pro Ser Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn 
    50                  55                  60


Lys Asp Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu 
65                  70                  75                  80


Ser Ser Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp 
                85                  90                  95


Ala Pro Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala 
            100                 105                 110


Gln Asp Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu 
        115                 120                 125


Pro His Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu 
    130                 135                 140


Ser Pro Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln 
145                 150                 155                 160


Val Ser Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly 
                165                 170                 175


Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala 
            180                 185                 190


Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala 
        195                 200                 205


Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala 
    210                 215                 220


Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp 
225                 230                 235                 240


Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser 
                245                 250                 255


Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val 
            260                 265                 270


Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln 
        275                 280                 285


Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser 
    290                 295                 300


Asp Gly Glu Gly Ala Ala 
305                 310


<210>  6292
<211>  1720
<212>  DNA
<213>  Homo sapiens

<400>  6292
ttccacatag gattctgcag agtttagcat tcaaagattc agctgtgtgc tgggaaggga     60

ctgaagctgc caccccccac cctgggggca gtcgcattct ggaagtcagc gtgtgctggc    120

tgcaggagcc tgggttcagt tgcagcctcc cactgggaca ggaacagcgt cggggtgggg    180

gtgtgacagg gaagcctcgg tgcctcggtg attggcttgg tcttgcaggg agcggctgcc    240

agcaggccgg ctggaggcgg ctttgcgctg ccccagcctg ggagccctca ggatgtgtgt    300

ggggtggagc ctgctaggga tcccagtgcc agggggtgcc gttgtgaggg atggacgcct    360

ctcccccgga gcagcacttt ggggccagct tgggccctgg ggatgagcca caggggaccc    420

acagcctatg cgtgtgagca tgtaacccgg gagccagctg ggcccctcgc ggggtgggca    480

gaaggacggg ctggcccagg accctcttct ttgagacatc ccggactcca tctcggatga    540

aagtgctttg agaaaccaca gagttttctg tttaatggaa gaaagaaatc cagcctctct    600

ccagagtggc ggtggccggc tagacagggt atcgctcccc tggggaactt gggtaagtcc    660

ataaatagct ctgctgacac aaaggagctc tgtctgggga aggcagccgc ttgacacggc    720

cgccaggagc tgccacagcc acggccgccc gcctgcggga ggagccgggt ggaaacctgg    780

gcgggcgagc tggcaggagc ggcagccagg agtcgcctgg gtccctgctg gagtatgctg    840

gatgtttgag acggaggcag atgagaagag ggagatggcc ttggaggaag ggaaggggcc    900

tggtgccgag gattccccac ccagcaagga gccctctcct ggccaggagc ttcctccagg    960

acaagacctt ccacccaaca aggactcccc ttctgggcag gaacccgctc ccagccaaga   1020

accactgtcc agcaaagact cagctacctc tgaaggatcc cctccaggcc cagatgctcc   1080

gcccagcaag gatgtgccac catgccagga accccctcca gcccaagacc tctcaccctg   1140

ccaggaccta cctgctggtc aagaacccct gcctcaccag gaccctctac tcaccaaaga   1200

cctccctgcc atccaggaat cccccacccg ggaccttcca ccctgtcaag atctgcctcc   1260

tagccaggtc tccctgccag ccaaggccct tactgaggac accatgagct ccggggacct   1320

actagcagct actggggacc cacctgcggc ccccaggcca gccttcgtga tccctgaggt   1380

ccggctggat agcacctaca gccagaaggc aggggcagag cagggctgct cgggagatga   1440

ggaggatgca gaagaggccg aggaggtgga ggagggggag gaaggggagg aggacgagga   1500

tgaggacacc agcgatgaca actacggaga gcgcagtgag gccaagcgca gcagcatgat   1560

cgagacgggc cagggggctg agggtggcct ctcactgcgt gtgcagaact cgctgcggcg   1620

ccggacgcac agcgagggca gcctgctgca ggagccccga gggccctgct ttgcctccga   1680

caccaccttg cactgctcag acggtgaggg cgccgcctcc                         1720


<210>  6293
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6293

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6294
<211>  1935
<212>  DNA
<213>  Homo sapiens

<400>  6294
ttccacatag gattctgcag agtttagcat tcaaagattc agctgtgtgc tgggaaggga     60

ctgaagctgc caccccccac cctgggggca gtcgcattct ggaagtcagc gtgtgctggc    120

tgcaggagcc tgggttcagt tgcagcctcc cactgggaca ggaacagcgt cggggtgggg    180

gtgtgacagg gaagcctcgg tgcctcggtg attggcttgg tcttgcaggg agcggctgcc    240

agcaggccgg ctggaggcgg ctttgcgctg ccccagcctg ggagccctca ggatgtgtgt    300

ggggtggagc ctgctaggga tcccagtgcc agggggtgcc gttgtgaggg atggacgcct    360

ctcccccgga gcagcacttt ggggccagct tgggccctgg ggatgagcca caggggaccc    420

acagcctatg cgtgtgagca tgtaacccgg gagccagctg ggcccctcgc ggggtgggca    480

gaaggacggg ctggcccagg accctcttct ttgagacatc ccggactcca tctcggatga    540

aagtgctttg agaaaccaca gagttttctg tttaatggaa gaaagaaatc cagcctctct    600

ccagagtggc ggtggccggc tagacaggag ccaaggacat gaagaacaag ctggggatct    660

tcagacggcg gaatgagtcc cctggagccc ctcccgcggg caaggcagac aaaatgatga    720

agtcattcaa gcccacctca gaggaagccc tcaagtgggg cgagtccttg gagaagctgc    780

tggttcacaa atacgggtta gcagtgttcc aagccttcct tcgcactgag ttcagtgagg    840

agaatctgga gttctggttg gcttgtgagg acttcaagaa ggtcaagtca cagtccaaga    900

tggcatccaa ggccaagaag atctttgctg aatacatcgc gatccaggca tgcaaggagg    960

tcaacctgga ctcctacacg cgggagcaca ccaaggacaa cctgcagagc gtcacgcggg   1020

gctgcttcga cctggcacag aagcgcatct tcgggctcat ggaaaaggac tcgtaccctc   1080

gctttctccg ttctgacctc tacctggacc ttattaacca gaagaagatg agtcccccgc   1140

tttaggggcc actggagtcg agctcagcgt tcacaccagg cgggctgggt cccctgccca   1200

cctgcctccc tgccccctgt gacggagggg gcaagcaagc ccccagaggc tgtgtctctg   1260

gacagacgga tagacatacg gaagcgaggc ctggaccaag agaggcccag gctactggag   1320

gagtagaagg atgggccccg tggggtcccc actgccccgg tacgaggggg cccaagaccc   1380

tggcaggtca ggggccctgg ccaagccaga tctggagctg ctgctccctg ctgcggagac   1440

cgcggaggct tcgcgttgac caagttcctt aaagaactgg ctgatggggc aggaggtcca   1500

ggcctgggct ctcgggccct cctagagggc cattggagct tgcagctcag acccccactt   1560

tgagttttat ttatttaaat agtagttgga tgcttggcac gtcgtcctgt aataggaaac   1620

ccttgcctca tcagttttcc tgatttacaa gtgcaatatt ttagccaatg ccttgggaga   1680

agctgccatg caaaggtgga caccattctc cagcttcagg ggatatgctc gtcccgggca   1740

ccggtggcag gcagctggcc ttctggacta aggcagcctg gggggacact gcagtctggc   1800

tacacacaga gatctggcac cccctgggtg gagtgtccct cgggggcttt gggaaagcat   1860

ggcaccctca gaccacacag tagccaagtt ctggagcaaa taaaaggcct gtgttatttc   1920

ttgttcttga ccctt                                                    1935


<210>  6295
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  6295

Met Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly 
1               5                   10                  15


Ala Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro 
            20                  25                  30


Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu 
        35                  40                  45


Val His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu 
    50                  55                  60


Phe Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys 
65                  70                  75                  80


Lys Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe 
                85                  90                  95


Ala Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser 
            100                 105                 110


Tyr Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly 
        115                 120                 125


Cys Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp 
    130                 135                 140


Ser Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn 
145                 150                 155                 160


Gln Lys Lys Met Ser Pro Pro Leu 
                165


<210>  6296
<211>  1103
<212>  DNA
<213>  Homo sapiens

<400>  6296
gattggcttg gtcttgcagg gagcggctgc cagcaggccg gctggaggcg gctttgcgct     60

gccccagcct gggagccctc aggatgtgtg tggggtggag cctgctaggg atcccagtgc    120

cagggggtgc cgttgtgagg gatggacgcc tctcccccgg agcagcactt tggggccagc    180

ttgggccctg gggatgagcc acaggggacc cacagcctat gcgtatgttt gagacggagg    240

cagatgagaa gagggagatg gccttggagg aagggaaggg gcctggtgcc gaggattccc    300

cacccagcaa ggagccctct cctggccagg agcttcctcc aggacaagac cttccaccca    360

acaaggactc cccttctggg caggaacccg ctcccagcca agaaccactg tccagcaaag    420

actcagctac ctctgaagga tcccctccag gcccagatgc tccgcccagc aaggatgtgc    480

caccatgcca ggaaccccct ccagcccaag acctctcacc ctgccaggac ctacctgctg    540

gtcaagaacc cctgcctcac caggaccctc tactcaccaa agacctccct gccatccagg    600

aatcccccac ccgggacctt ccaccctgtc aagatctgcc tcctagccag gtctccctgc    660

cagccaaggc ccttactgag gacaccatga gctccgggga cctactagca gctactgggg    720

acccacctgc ggcccccagg ccagccttcg tgatccctga ggtccggctg gatagcacct    780

acagccagaa ggcaggggca gagcagggct gctcgggaga tgaggaggat gcagaagagg    840

ccgaggaggt ggaggagggg gaggaagggg aggaggacga ggatgaggac accagcgatg    900

acaactacgg agagcgcagt gaggccaagc gcagcagcat gatcgagacg ggccaggggg    960

ctgagggtgg cctctcactg cgtgtgcaga actcgctgcg gcgccggacg cacagcgagg   1020

gcagcctgct gcaggagccc cgagggccct gctttgcctc cgacaccacc ttgcactgct   1080

cagacggtga gggcgccgcc tcc                                           1103


<210>  6297
<211>  294
<212>  PRT
<213>  Homo sapiens

<400>  6297

Met Arg Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu 
1               5                   10                  15


Glu Glu Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu 
            20                  25                  30


Pro Ser Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn 
        35                  40                  45


Lys Asp Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu 
    50                  55                  60


Ser Ser Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp 
65                  70                  75                  80


Ala Pro Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala 
                85                  90                  95


Gln Asp Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu 
            100                 105                 110


Pro His Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu 
        115                 120                 125


Ser Pro Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln 
    130                 135                 140


Val Ser Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly 
145                 150                 155                 160


Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala 
                165                 170                 175


Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala 
            180                 185                 190


Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala 
        195                 200                 205


Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp 
    210                 215                 220


Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser 
225                 230                 235                 240


Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val 
                245                 250                 255


Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln 
            260                 265                 270


Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser 
        275                 280                 285


Asp Gly Glu Gly Ala Ala 
    290


<210>  6298
<211>  1588
<212>  DNA
<213>  Homo sapiens

<400>  6298
aggatgtgtg tggggtggag cctgctaggg atcccagtgc cagggggtgc cgttgtgagg     60

gatggacgcc tctcccccgg agcagcactt tggggccagc ttgggccctg gggatgagcc    120

acaggggacc cacagcctat gcgtgtgagc atgtaacccg ggagccagct gggcccctcg    180

cggggtgggc agaaggacgg gctggcccag gaccctcttc tttgagacat cccggactcc    240

atctcggatg aaagtgcttt gagaaaccac agagttttct gtttaatgga agaaagaaat    300

ccagcctctc tccagagtgg cggtggccgg ctagacaggg tgtgtgtttg ggaaaggcgc    360

tggaggagga ggaagaggag gaggacaagt aggaggagga ggaagaggag gagggacggg    420

tgatgcaagg gttttgaaag cgctacctag atgtgggagg tggaacctgg tcatttggtt    480

ctgcttttcc tagcaggtat cgctcccctg gggaacttgg gtaagtccat aaatagctct    540

gctgacacaa aggagctctg tctggggaag gcagccgctt gacacggccg ccaggagctg    600

ccacagccac ggccgcccgc ctgcgggagg agccgggtgg aaacctgggc gggcgagctg    660

gcaggagcgg cagccaggag tcgcctgggt ccctgctgga gtatgctgga tgtttgagac    720

ggaggcagat gagaagaggg agatggcctt ggaggaaggg aaggggcctg gtgccgagga    780

ttccccaccc agcaaggagc cctctcctgg ccaggagctt cctccaggac aagaccttcc    840

acccaacaag gactcccctt ctgggcagga acccgctccc agccaagaac cactgtccag    900

caaagactca gctacctctg aaggatcccc tccaggccca gatgctccgc ccagcaagga    960

tgtgccacca tgccaggaac cccctccagc ccaagacctc tcaccctgcc aggacctacc   1020

tgctggtcaa gaacccctgc ctcaccagga ccctctactc accaaagacc tccctgccat   1080

ccaggaatcc cccacccggg accttccacc ctgtcaagat ctgcctccta gccaggtctc   1140

cctgccagcc aaggccctta ctgaggacac catgagctcc ggggacctac tagcagctac   1200

tggggaccca cctgcggccc ccaggccagc cttcgtgatc cctgaggtcc ggctggatag   1260

cacctacagc cagaaggcag gggcagagca gggctgctcg ggagatgagg aggatgcaga   1320

agaggccgag gaggtggagg agggggagga aggggaggag gacgaggatg aggacaccag   1380

cgatgacaac tacggagagc gcagtgaggc caagcgcagc agcatgatcg agacgggcca   1440

gggggctgag ggtggcctct cactgcgtgt gcagaactcg ctgcggcgcc ggacgcacag   1500

cgagggcagc ctgctgcagg agccccgagg gccctgcttt gcctccgaca ccaccttgca   1560

ctgctcagac ggtgagggcg ccgcctcc                                      1588


<210>  6299
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6299

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6300
<211>  1018
<212>  DNA
<213>  Homo sapiens

<400>  6300
agtgccaggg ggtgccgttg tgagggatgg acgcctctcc cccggagcag cactttgggg     60

ccagcttggg ccctggggat gagccacagg ggacccacag cctatgcgag tcgcctgggt    120

ccctgctgga gtatgctgga tgtttgagac ggaggcagat gagaagaggg agatggcctt    180

ggaggaaggg aaggggcctg gtgccgagga ttccccaccc agcaaggagc cctctcctgg    240

ccaggagctt cctccaggac aagaccttcc acccaacaag gactcccctt ctgggcagga    300

acccgctccc agccaagaac cactgtccag caaagactca gctacctctg aaggatcccc    360

tccaggccca gatgctccgc ccagcaagga tgtgccacca tgccaggaac cccctccagc    420

ccaagacctc tcaccctgcc aggacctacc tgctggtcaa gaacccctgc ctcaccagga    480

ccctctactc accaaagacc tccctgccat ccaggaatcc cccacccggg accttccacc    540

ctgtcaagat ctgcctccta gccaggtctc cctgccagcc aaggccctta ctgaggacac    600

catgagctcc ggggacctac tagcagctac tggggaccca cctgcggccc ccaggccagc    660

cttcgtgatc cctgaggtcc ggctggatag cacctacagc cagaaggcag gggcagagca    720

gggctgctcg ggagatgagg aggatgcaga agaggccgag gaggtggagg agggggagga    780

aggggaggag gacgaggatg aggacaccag cgatgacaac tacggagagc gcagtgaggc    840

caagcgcagc agcatgatcg agacgggcca gggggctgag ggtggcctct cactgcgtgt    900

gcagaactcg ctgcggcgcc ggacgcacag cgagggcagc ctgctgcagg agccccgagg    960

gccctgcttt gcctccgaca ccaccttgca ctgctcagac ggtgagggcg ccgcctcc     1018


<210>  6301
<211>  304
<212>  PRT
<213>  Homo sapiens

<400>  6301

Met Arg Val Ala Trp Val Pro Ala Gly Val Cys Trp Met Phe Glu Thr 
1               5                   10                  15


Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu Gly Lys Gly Pro 
            20                  25                  30


Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser Pro Gly Gln Glu 
        35                  40                  45


Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp Ser Pro Ser Gly 
    50                  55                  60


Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser Lys Asp Ser Ala 
65                  70                  75                  80


Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro Pro Ser Lys Asp 
                85                  90                  95


Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp Leu Ser Pro Cys 
            100                 105                 110


Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His Gln Asp Pro Leu 
        115                 120                 125


Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro Thr Arg Asp Leu 
    130                 135                 140


Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser Leu Pro Ala Lys 
145                 150                 155                 160


Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu Leu Ala Ala Thr 
                165                 170                 175


Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val Ile Pro Glu Val 
            180                 185                 190


Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys 
        195                 200                 205


Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu Val Glu Glu Gly 
    210                 215                 220


Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr 
225                 230                 235                 240


Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile Glu Thr Gly Gln 
                245                 250                 255


Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn Ser Leu Arg Arg 
            260                 265                 270


Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys 
        275                 280                 285


Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly Glu Gly Ala Ala 
    290                 295                 300


<210>  6302
<211>  1201
<212>  DNA
<213>  Homo sapiens

<400>  6302
agtgccaggg ggtgccgttg tgagggatgg acgcctctcc cccggagcag cactttgggg     60

ccagcttggg ccctggggat gagccacagg ggacccacag cctatgcgtg tatcgctccc    120

ctggggaact tgggtaagtc cataaatagc tctgctgaca caaaggagct ctgtctgggg    180

aaggcagccg cttgacacgg ccgccaggag ctgccacagc cacggccgcc cgcctgcggg    240

aggagccggg tggaaacctg ggcgggcgag ctggcaggag cggcagccag gagtcgcctg    300

ggtccctgct ggagtatgct ggatgtttga gacggaggca gatgagaaga gggagatggc    360

cttggaggaa gggaaggggc ctggtgccga ggattcccca cccagcaagg agccctctcc    420

tggccaggag cttcctccag gacaagacct tccacccaac aaggactccc cttctgggca    480

ggaacccgct cccagccaag aaccactgtc cagcaaagac tcagctacct ctgaaggatc    540

ccctccaggc ccagatgctc cgcccagcaa ggatgtgcca ccatgccagg aaccccctcc    600

agcccaagac ctctcaccct gccaggacct acctgctggt caagaacccc tgcctcacca    660

ggaccctcta ctcaccaaag acctccctgc catccaggaa tcccccaccc gggaccttcc    720

accctgtcaa gatctgcctc ctagccaggt ctccctgcca gccaaggccc ttactgagga    780

caccatgagc tccggggacc tactagcagc tactggggac ccacctgcgg cccccaggcc    840

agccttcgtg atccctgagg tccggctgga tagcacctac agccagaagg caggggcaga    900

gcagggctgc tcgggagatg aggaggatgc agaagaggcc gaggaggtgg aggaggggga    960

ggaaggggag gaggacgagg atgaggacac cagcgatgac aactacggag agcgcagtga   1020

ggccaagcgc agcagcatga tcgagacggg ccagggggct gagggtggcc tctcactgcg   1080

tgtgcagaac tcgctgcggc gccggacgca cagcgagggc agcctgctgc aggagccccg   1140

agggccctgc tttgcctccg acaccacctt gcactgctca gacggtgagg gcgccgcctc   1200

c                                                                   1201


<210>  6303
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6303

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6304
<211>  1364
<212>  DNA
<213>  Homo sapiens

<400>  6304
agtgccaggg ggtgccgttg tgagggatgg acgcctctcc cccggagcag cactttgggg     60

ccagcttggg ccctggggat gagccacagg ggacccacag cctatgcgtg tgagcatgta    120

acccgggagc cagctgggcc cctcgcgggg tgggcagaag gacgggctgg cccaggaccc    180

tcttctttga gacatcccgg actccatctc ggatgaaagt gctttgagaa accacagagt    240

tttctgttta atggaagaaa gaaatccagc ctctctccag agtggcggtg gccggctaga    300

cagggtgtgt gtttgggaaa ggcgctggag gaggaggaag aggaggagga caagtaggag    360

gaggaggaag aggaggaggg acgggtgatg caagggtttt gaaagcgcta cctagatgtg    420

ggaggtggaa cctggtcatt tggttctgct tttcctagca ggtatcgctc ccctggggaa    480

cttggatgtt tgagacggag gcagatgaga agagggagat ggccttggag gaagggaagg    540

ggcctggtgc cgaggattcc ccacccagca aggagccctc tcctggccag gagcttcctc    600

caggacaaga ccttccaccc aacaaggact ccccttctgg gcaggaaccc gctcccagcc    660

aagaaccact gtccagcaaa gactcagcta cctctgaagg atcccctcca ggcccagatg    720

ctccgcccag caaggatgtg ccaccatgcc aggaaccccc tccagcccaa gacctctcac    780

cctgccagga cctacctgct ggtcaagaac ccctgcctca ccaggaccct ctactcacca    840

aagacctccc tgccatccag gaatccccca cccgggacct tccaccctgt caagatctgc    900

ctcctagcca ggtctccctg ccagccaagg cccttactga ggacaccatg agctccgggg    960

acctactagc agctactggg gacccacctg cggcccccag gccagccttc gtgatccctg   1020

aggtccggct ggatagcacc tacagccaga aggcaggggc agagcagggc tgctcgggag   1080

atgaggagga tgcagaagag gccgaggagg tggaggaggg ggaggaaggg gaggaggacg   1140

aggatgagga caccagcgat gacaactacg gagagcgcag tgaggccaag cgcagcagca   1200

tgatcgagac gggccagggg gctgagggtg gcctctcact gcgtgtgcag aactcgctgc   1260

ggcgccggac gcacagcgag ggcagcctgc tgcaggagcc ccgagggccc tgctttgcct   1320

ccgacaccac cttgcactgc tcagacggtg agggcgccgc ctcc                    1364


<210>  6305
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  6305

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala 
    290


<210>  6306
<211>  392
<212>  DNA
<213>  Homo sapiens

<400>  6306
ccaccagagt tgtaaacata catgtgtgta cgtgcacaca gaggcacaca ccgtatggtg     60

tgtgatttca gagcaagtgt ttggaaccag acctggatat aaatcctgct ttcaccaact    120

ttggctgcat caatgcctgc ccagggccta gtctgcaaag gccctccaaa gggattctcc    180

tttccatctt ctccccactg tctcactatg tgaccttgtc cagctgaaaa gcagatggag    240

caaaacgctg ccgcgctgcc tcctgaatgc ctgctcagtg tcagatccac gccaagcacc    300

tcacctacat cgctgcattt aataacagcc acctatgaga tgggcgctag tggcactccc    360

actgctatca ggacacagaa tccattcaca tg                                  392


<210>  6307
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  6307

Met Glu Gln Asn Ala Ala Ala Leu Pro Pro Glu Cys Leu Leu Ser Val 
1               5                   10                  15


Arg Ser Thr Pro Ser Thr Ser Pro Thr Ser Leu His Leu Ile Thr Ala 
            20                  25                  30


Thr Tyr Glu Met Gly Ala Ser Gly Thr Pro Thr Ala Ile Arg Thr Gln 
        35                  40                  45


Asn Pro Phe 
    50


<210>  6308
<211>  2799
<212>  DNA
<213>  Homo sapiens

<400>  6308
ttctcggctg atctctctgg gtaggtgccc tctgggggca gtacccctgc ctgagtggca     60

cttcccctcc tggctttgtt tggtttggcc tcgatttaga acagggttgg cagaggcagg    120

ctgacttgca tttctggttt tgggtttgtt gctgcacttt ccccaagggg tgggcgggct    180

ctgactgaca gtcaccactg ggacaggcct gggccccacc ctcaccaccc aggaaagggg    240

aaatgcggcc cgctccccac tcagtgccac tctgtgccac tccgtgccag gccctgaggg    300

cacccggttg ctgcttcctt ccgtctttcc ccaaggacta tcagagatgc cagcgtgacc    360

cctgacacgt gtgtgcagca gcctgcagct gccccaagcc atggctgaac actgactccc    420

agctgtgggg cttcaccatt acagactccc cagggcttca aagacttctc agcttcgagc    480

atggcttttg gctgtcaggg cagctgtaca atagtggatg tttgagacgg aggcagatga    540

gaagagggag atggccttgg aggaagggaa ggggcctggt gccgaggatt ccccacccag    600

caaggagccc tctcctggcc aggagcttcc tccaggacaa gaccttccac ccaacaagga    660

ctccccttct gggcaggaac ccgctcccag ccaagaacca ctgtccagca aagactcagc    720

tacctctgaa ggatcccctc caggcccaga tgctccgccc agcaaggatg tgccaccatg    780

ccaggaaccc cctccagccc aagacctctc accctgccag gacctacctg ctggtcaaga    840

acccctgcct caccaggacc ctctactcac caaagacctc cctgccatcc aggaatcccc    900

cacccgggac cttccaccct gtcaagatct gcctcctagc caggtctccc tgccagccaa    960

ggcccttact gaggacacca tgagctccgg ggacctacta gcagctactg gggacccacc   1020

tgcggccccc aggccagcct tcgtgatccc tgaggtccgg ctggatagca cctacagcca   1080

gaaggcaggg gcagagcagg gctgctcggg agatcaccag cgatgacaac tacggagagc   1140

gcagtgaggc caagcgcagc agcatgatcg agacgggcca gggggctgag ggtggcctct   1200

cactgcgtgt gcagaactcg ctgcggcgcc ggacgcacag cgagggcagc ctgctgcagg   1260

agccccgagg gccctgcttt gcctccgaca ccaccttgca ctgctcagac ggtgagggcg   1320

ccgcctccac ctggggcatg ccttcgccca gcaccctcaa gaaagagctg ggccgcaatg   1380

gtggctccat gcaccacctt tccctcttct tcacaggaca caggaagatg agcggggctg   1440

acaccgttgg ggatgatgac gaagcctccc ggaagagaaa gagcaaaaac ctagccaagg   1500

acatgaagaa caagctgggg atcttcagac ggcggaatga gtcccctgga gcccctcccg   1560

cgggcaaggc agacaaaatg atgaagtcat tcaagcccac ctcagaggaa gccctcaagt   1620

ggggcgagtc cttggagaag ctgctggttc acaaatacgg gttagcagtg ttccaagcct   1680

tccttcgcac tgagttcagt gaggagaatc tggagttctg gttggcttgt gaggacttca   1740

agaaggtcaa gtcacagtcc aagatggcat ccaaggccaa gaagatcttt gctgaataca   1800

tcgcgatcca ggcatgcaag gaggtcaacc tggactccta cacgcgggag cacaccaagg   1860

acaacctgca gagcgtcacg cggggctgct tcgacctggc acagaagcgc atcttcgggc   1920

tcatggaaaa ggactcgtac cctcgctttc tccgttctga cctctacctg gaccttatta   1980

accagaagaa gatgagtccc ccgctttagg ggccactgga gtcgagctca gcgttcacac   2040

caggcgggct gggtcccctg cccacctgcc tccctgcccc ctgtgacgga gggggcaagc   2100

aagcccccag aggctgtgtc tctggacaga cggatagaca tacggaagcg aggcctggac   2160

caagagaggc ccaggctact ggaggagtag aaggatgggc cccgtggggt ccccactgcc   2220

ccggtacgag ggggcccaag accctggcag gtcaggggcc ctggccaagc cagatctgga   2280

gctgctgctc cctgctgcgg agaccgcgga ggcttcgcgt tgaccaagtt ccttaaagaa   2340

ctggctgatg gggcaggagg tccaggcctg ggctctcggg ccctcctaga gggccattgg   2400

agcttgcagc tcagaccccc actttgagtt ttatttattt aaatagtagt tggatgcttg   2460

gcacgtcgtc ctgtaatagg aaacccttgc ctcatcagtt ttcctgattt acaagtgcaa   2520

tattttagcc aatgccttgg gagaagctgc catgcaaagg tggacaccat tctccagctt   2580

caggggatat gctcgtcccg ggcaccggtg gcaggcagct ggccttctgg actaaggcag   2640

cctgggggga cactgcagtc tggctacaca cagagatctg gcaccccctg ggtggagtgt   2700

ccctcggggg ctttgggaaa gcatggcacc ctcagaccac acagtagcca agttctggag   2760

caaataaaag gcctgtgtta tttcttgttc ttgaccctt                          2799


<210>  6309
<211>  281
<212>  PRT
<213>  Homo sapiens

<400>  6309

Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val 
1               5                   10                  15


Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln 
            20                  25                  30


Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser 
        35                  40                  45


Asp Gly Glu Gly Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr 
    50                  55                  60


Leu Lys Lys Glu Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser 
65                  70                  75                  80


Leu Phe Phe Thr Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly 
                85                  90                  95


Asp Asp Asp Glu Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Ala Lys 
            100                 105                 110


Asp Met Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro 
        115                 120                 125


Gly Ala Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys 
    130                 135                 140


Pro Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu 
145                 150                 155                 160


Leu Val His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr 
                165                 170                 175


Glu Phe Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe 
            180                 185                 190


Lys Lys Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile 
        195                 200                 205


Phe Ala Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp 
    210                 215                 220


Ser Tyr Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg 
225                 230                 235                 240


Gly Cys Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys 
                245                 250                 255


Asp Ser Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile 
            260                 265                 270


Asn Gln Lys Lys Met Ser Pro Pro Leu 
        275                 280


<210>  6310
<211>  2867
<212>  DNA
<213>  Homo sapiens

<400>  6310
ttctcggctg atctctctgg gtaggtgccc tctgggggca gtacccctgc ctgagtggca     60

cttcccctcc tggctttgtt tggtttggcc tcgatttaga acagggttgg cagaggcagg    120

ctgacttgca tttctggttt tgggtttgtt gctgcacttt ccccaagggg tgggcgggct    180

ctgactgaca gtcaccactg ggacaggcct gggccccacc ctcaccaccc aggaaagggg    240

aaatgcggcc cgctccccac tcagtgccac tctgtgccac tccgtgccag gccctgaggg    300

cacccggttg ctgcttcctt ccgtctttcc ccaaggacta tcagagatgc cagcgtgacc    360

cctgacacgt gtgtgcagca gcctgcagct gccccaagcc atggctgaac actgactccc    420

agctgtgggg cttcaccatt acagactccc cagggcttca aagacttctc agcttcgagc    480

atggcttttg gctgtcaggg cagctgtaca atagtggatg tttgagacgg aggcagatga    540

gaagagggag atggccttgg aggaagggaa ggggcctggt gccgaggatt ccccacccag    600

caaggagccc tctcctggcc aggagcttcc tccaggacaa gaccttccac ccaacaagga    660

ctccccttct gggcaggaac ccgctcccag ccaagaacca ctgtccagca aagactcagc    720

tacctctgaa ggatcccctc caggcccaga tgctccgccc agcaaggatg tgccaccatg    780

ccaggaaccc cctccagccc aagacctctc accctgccag gacctacctg ctggtcaaga    840

acccctgcct caccaggacc ctctactcac caaagacctc cctgccatcc aggaatcccc    900

cacccgggac cttccaccct gtcaagatct gcctcctagc caggtctccc tgccagccaa    960

ggcccttact gaggacacca tgagctccgg ggacctacta gcagctactg gggacccacc   1020

tgcggccccc aggccagcct tcgtgatccc tgaggtccgg ctggatagca cctacagcca   1080

gaaggcaggg gcagagcagg gctgctcggg agatgaggag gatgcagaag aggccgagga   1140

ggtggaggag ggggaggaag gggaggagga cgaggatgag gacaccagcg atgacaacta   1200

cggagagcgc agtgaggcca agcgcagcag catgatcgag acgggccagg gggctgaggg   1260

tggcctctca ctgcgtgtgc agaactcgct gcggcgccgg acgcacagcg agggcagcct   1320

gctgcaggag ccccgagggc cctgctttgc ctccgacacc accttgcact gctcagacgg   1380

tgagggcgcc gcctccacct ggggcatgcc ttcgcccagc accctcaaga aagagctggg   1440

ccgcaatggt ggctccatgc accacctttc cctcttcttc acaggacaca ggaagatgag   1500

cggggctgac accgttgggg atgatgacga agcctcccgg aagagaaaga gcaaaaacct   1560

agccaaggac atgaagaaca agctggggat cttcagacgg cggaatgagt cccctggagc   1620

ccctcccgcg ggcaaggcag acaaaatgat gaagtcattc aagcccacct cagaggaagc   1680

cctcaagtgg ggcgagtcct tggagaagct gctggttcac aaatacgggt tagcagtgtt   1740

ccaagccttc cttcgcactg agttcagtga ggagaatctg gagttctggt tggcttgtga   1800

ggacttcaag aaggtcaagt cacagtccaa gatggcatcc aaggccaaga agatctttgc   1860

tgaatacatc gcgatccagg catgcaagga ggtcaacctg gactcctaca cgcgggagca   1920

caccaaggac aacctgcaga gcgtcacgcg gggctgcttc gacctggcac agaagcgcat   1980

cttcgggctc atggaaaagg actcgtaccc tcgctttctc cgttctgacc tctacctgga   2040

ccttattaac cagaagaaga tgagtccccc gctttagggg ccactggagt cgagctcagc   2100

gttcacacca ggcgggctgg gtcccctgcc cacctgcctc cctgccccct gtgacggagg   2160

gggcaagcaa gcccccagag gctgtgtctc tggacagacg gatagacata cggaagcgag   2220

gcctggacca agagaggccc aggctactgg aggagtagaa ggatgggccc cgtggggtcc   2280

ccactgcccc ggtacgaggg ggcccaagac cctggcaggt caggggccct ggccaagcca   2340

gatctggagc tgctgctccc tgctgcggag accgcggagg cttcgcgttg accaagttcc   2400

ttaaagaact ggctgatggg gcaggaggtc caggcctggg ctctcgggcc ctcctagagg   2460

gccattggag cttgcagctc agacccccac tttgagtttt atttatttaa atagtagttg   2520

gatgcttggc acgtcgtcct gtaataggaa acccttgcct catcagtttt cctgatttac   2580

aagtgcaata ttttagccaa tgccttggga gaagctgcca tgcaaaggtg gacaccattc   2640

tccagcttca ggggatatgc tcgtcccggg caccggtggc aggcagctgg ccttctggac   2700

taaggcagcc tggggggaca ctgcagtctg gctacacaca gagatctggc accccctggg   2760

tggagtgtcc ctcgggggct ttgggaaagc atggcaccct cagaccacac agtagccaag   2820

ttctggagca aataaaaggc ctgtgttatt tcttgttctt gaccctt                 2867


<210>  6311
<211>  519
<212>  PRT
<213>  Homo sapiens

<400>  6311

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr Leu Lys 
    290                 295                 300


Lys Glu Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser Leu Phe 
305                 310                 315                 320


Phe Thr Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly Asp Asp 
                325                 330                 335


Asp Glu Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Ala Lys Asp Met 
            340                 345                 350


Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly Ala 
        355                 360                 365


Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro Thr 
    370                 375                 380


Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu Val 
385                 390                 395                 400


His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu Phe 
                405                 410                 415


Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys Lys 
            420                 425                 430


Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe Ala 
        435                 440                 445


Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr 
    450                 455                 460


Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly Cys 
465                 470                 475                 480


Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp Ser 
                485                 490                 495


Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln 
            500                 505                 510


Lys Lys Met Ser Pro Pro Leu 
        515


<210>  6312
<211>  3999
<212>  DNA
<213>  Homo sapiens

<400>  6312
aaaggggaaa tgcggcccgc tccccactca gtgccactct gtgccactcc gtgccaggcc     60

ctgagggcac ccggttgctg cttccttccg tctttcccca aggactatca gaggcaggtg    120

gctgggccag ggggtgggtc ggggggaggt ctggccatgt ggtagggtga taggactgag    180

gggccccagg gagctggctg cagggcagtt tgtttctcct gatggagaat gctccctggt    240

gggtggggcg atgggctggg gactggtttg ttcatgggga cagagatcag aagtgggctt    300

gagaagaaca gggccagaag gcctggactc tggccccagc ctagccccta atttgtgcag    360

ggtggctttg ggcaagtcac taagtcactg tctagactgg gccctcagcc ttcctgtcta    420

cccaatggag ggtctttctg tccacctggg aacagcctga taggactgaa gcacagccct    480

tagtttccag atgagaattc tggactggag gccctgacat tacaattgcc aacactgact    540

ctggtgtttg gcaaaatttg gtgtatgtgg gaaacacgtg cctctggttg aggtccttaa    600

cttcagaatt tccctctaga tcaatgcttt ttaaagcact aactccaaca ccaccatctt    660

ctgtaggagc tttcgagctt tccagctttt ccagcatacg ctcctgatct gttactcagg    720

catgctggtt atcccatttc atacgtggac accttgaggc ctaaaggttg gtgactggct    780

ctacctgaca cctctgtgtg attctaggtt gccccttgct cctctctggg cctcagcctt    840

tctgtctatg cagtggggat ttcggatcgc tgttgtttca gagtctgagg ctatgaggtc    900

tgagagggcc cttgtgtgga gtcacctctg agctgcaggc aggatttcca gggcaagaag    960

gccacagcat cagcaggcac ctgtctttgg cctgtgagcc atagcctaag gcgtgccctt   1020

cccgaccttg gccagatcac gctagagtcc tccaaggcct cccctccctt gcccagccac   1080

cttctctgct ctgcagggct ccactttcac tttcacactc ccaggctgtg gctcttaccc   1140

gtgccgagct ttcacatccg ctcacatctg tgctcccaga tgccagcgtg acccctgaca   1200

cgtgtgtgca gcagcctgca gctgccccaa gccatggctg aacactgact cccagctgtg   1260

gggcttcacc attacagact ccccagggct tcaaagactt ctcagcttcg agcatggctt   1320

ttggctgtca gggcagctgt acaatagtgg atgtttgaga cggaggcaga tgagaagagg   1380

gagatggcct tggaggaagg gaaggggcct ggtgccgagg attccccacc cagcaaggag   1440

ccctctcctg gccaggagct tcctccagga caagaccttc cacccaacaa ggactcccct   1500

tctgggcagg aacccgctcc cagccaagaa ccactgtcca gcaaagactc agctacctct   1560

gaaggatccc ctccaggccc agatgctccg cccagcaagg atgtgccacc atgccaggaa   1620

ccccctccag cccaagacct ctcaccctgc caggacctac ctgctggtca agaacccctg   1680

cctcaccagg accctctact caccaaagac ctccctgcca tccaggaatc ccccacccgg   1740

gaccttccac cctgtcaaga tctgcctcct agccaggtct ccctgccagc caaggccctt   1800

actgaggaca ccatgagctc cggggaccta ctagcagcta ctggggaccc acctgcggcc   1860

cccaggccag ccttcgtgat ccctgaggtc cggctggata gcacctacag ccagaaggca   1920

ggggcagagc agggctgctc gggagatgag gaggatgcag aagaggccga ggaggtggag   1980

gagggggagg aaggggagga ggacgaggat gaggacacca gcgatgacaa ctacggagag   2040

cgcagtgagg ccaagcgcag cagcatgatc gagacgggcc agggggctga gggtggcctc   2100

tcactgcgtg tgcagaactc gctgcggcgc cggacgcaca gcgagggcag cctgctgcag   2160

gagccccgag ggccctgctt tgcctccgac accaccttgc actgctcaga cggtgagggc   2220

gccgcctcca cctggggcat gccttcgccc agcaccctca agaaagagct gggccgcaat   2280

ggtggctcca tgcaccacct ttccctcttc ttcacaggac acaggaagat gagcggggct   2340

gacaccgttg gggatgatga cgaagcctcc cggaagagaa agagcaaaaa cctgtacgtt   2400

gggaagatcc ctggcttctg cgctcctctt cctcccttgc cccagggctt gtctctcctc   2460

taggggtcca ggtggggaga agaggttgtg cctggtcccg cccacaaccc cagacagaca   2520

ccaaggaaaa actggatctt ggaactttgc agtgacccca aagtggggtc acctgggtcc   2580

tgagcattct ctccaagtga ggcaaagtgc tgattcagta cccggaagcc acagtgaacc   2640

agaagcaacc agcccgtttg ccctggcttt agcccagctt ctgagccaag cagggaccaa   2700

gtgacttcaa caactccttt gctccctctg ggcccaagag tgacctgaga aggggtggaa   2760

ctgacagtca ttggctcctc tttctcttcc tgagctcctg aatgctaata gtctcaggca   2820

ttgccaggag ggggcgctgc tggcccagct gccgaatccc gcactcgcca agcctttctg   2880

gccacactca ggccttctta tactataggg tgtttgttag aggtgtcaat gaaaaagatg   2940

tgtgtgtggg ttctcaggtc ttcttctacc cccaggccta agaccctgga gactcggggg   3000

aggtataggg aggaggcagt ggggtgcatg cacagtgaca cctccagagg aagcccctcc   3060

ccaccaggtc ctgtagcacc caccactagg caggaattgg gctataggga ggagcctcct   3120

gcaaccctct tctctggcct tgaccgtggg tggggtccac taccctagaa agccttcctc   3180

accccagctg ccttgacctc tccagctttc tgcagcaact gttggcttct cttactccac   3240

agccaattgc attttcttag caaggtgaaa tgcataaacc aaaacagtcc cttgcaccaa   3300

ccatcttcac ttaacctttt gtaggatgag agaggatcca gggggtgcca ggactgttga   3360

atgtggtgct ggaagtggga ggtgtaggga agcagtgtgt ggcgcagagg gcaggcatcc   3420

cgggtgctgg agcagccctg tctagcctcc tttcaatgta ggtgctgcct tttgaattgc   3480

ctgaagccca cacttttttt ttttggagac agagtctcct tctgtcaccc aggctggagt   3540

gcgatcttgg cttgctgcaa cctccgcctc ccaagttcaa gcagttcttg tccctcagcc   3600

tcccaagtag ctgcgattac aggtgtgtgc catcacaccc agcaaatttt ttttgtactt   3660

ttagtagaga tgggggtttt gccatgttgg ccaggctgtt ctcaaactcc tggcctcaag   3720

tgatcttccc gcctcggcct cccaaagtgc tgggattaca gacatgagcc accatgcctg   3780

gcctctgaag gtcatactct taaaagctta gacgaagagt cttagaacat ctacggtaat   3840

aataagaata accattaatg tttattatgc cccgcactgt tctgtgtgta tttcatatgt   3900

aatctaattt aatctttacc actactttta ttttccgttc tgttctttct tattgacctt   3960

acccttattt tacacgtgaa taaactactg tgcaaagag                          3999


<210>  6313
<211>  370
<212>  PRT
<213>  Homo sapiens

<400>  6313

Met Phe Glu Thr Glu Ala Asp Glu Lys Arg Glu Met Ala Leu Glu Glu 
1               5                   10                  15


Gly Lys Gly Pro Gly Ala Glu Asp Ser Pro Pro Ser Lys Glu Pro Ser 
            20                  25                  30


Pro Gly Gln Glu Leu Pro Pro Gly Gln Asp Leu Pro Pro Asn Lys Asp 
        35                  40                  45


Ser Pro Ser Gly Gln Glu Pro Ala Pro Ser Gln Glu Pro Leu Ser Ser 
    50                  55                  60


Lys Asp Ser Ala Thr Ser Glu Gly Ser Pro Pro Gly Pro Asp Ala Pro 
65                  70                  75                  80


Pro Ser Lys Asp Val Pro Pro Cys Gln Glu Pro Pro Pro Ala Gln Asp 
                85                  90                  95


Leu Ser Pro Cys Gln Asp Leu Pro Ala Gly Gln Glu Pro Leu Pro His 
            100                 105                 110


Gln Asp Pro Leu Leu Thr Lys Asp Leu Pro Ala Ile Gln Glu Ser Pro 
        115                 120                 125


Thr Arg Asp Leu Pro Pro Cys Gln Asp Leu Pro Pro Ser Gln Val Ser 
    130                 135                 140


Leu Pro Ala Lys Ala Leu Thr Glu Asp Thr Met Ser Ser Gly Asp Leu 
145                 150                 155                 160


Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala Pro Arg Pro Ala Phe Val 
                165                 170                 175


Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr Ser Gln Lys Ala Gly Ala 
            180                 185                 190


Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp Ala Glu Glu Ala Glu Glu 
        195                 200                 205


Val Glu Glu Gly Glu Glu Gly Glu Glu Asp Glu Asp Glu Asp Thr Ser 
    210                 215                 220


Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala Lys Arg Ser Ser Met Ile 
225                 230                 235                 240


Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu Ser Leu Arg Val Gln Asn 
                245                 250                 255


Ser Leu Arg Arg Arg Thr His Ser Glu Gly Ser Leu Leu Gln Glu Pro 
            260                 265                 270


Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr Leu His Cys Ser Asp Gly 
        275                 280                 285


Glu Gly Ala Ala Ser Thr Trp Gly Met Pro Ser Pro Ser Thr Leu Lys 
    290                 295                 300


Lys Glu Leu Gly Arg Asn Gly Gly Ser Met His His Leu Ser Leu Phe 
305                 310                 315                 320


Phe Thr Gly His Arg Lys Met Ser Gly Ala Asp Thr Val Gly Asp Asp 
                325                 330                 335


Asp Glu Ala Ser Arg Lys Arg Lys Ser Lys Asn Leu Tyr Val Gly Lys 
            340                 345                 350


Ile Pro Gly Phe Cys Ala Pro Leu Pro Pro Leu Pro Gln Gly Leu Ser 
        355                 360                 365


Leu Leu 
    370


<210>  6314
<211>  598
<212>  DNA
<213>  Homo sapiens

<400>  6314
aaatgcggcc cgctccccac tcagtgccac tctgtgccac tccgtgccag gccctgaggg     60

cacccggttg ctgcttcctt ccgtctttcc ccaaggacta tcagaggttg ccccttgctc    120

ctctctgggc ctcagccttt ctgtctatgc agtggggatt tcggatcgct gttgtttcag    180

agtctgaggc tatgaggtct gagagggccc ttgtgtggag tcacctctga gctgcaggca    240

ggatttccag ggcaagaagg ccacagcatc agcaggcacc tgtctttggc ctgtgagcca    300

tagcctaagg cgtgcccttc ccgaccttgg ccagatcacg ctagagtcct ccaaggcctc    360

ccctcccttg cccagccacc ttctctgctc tgcagggctc cactttcact ttcacactcc    420

caggctgtgg ctcttacccg tgccgagctt tcacatccgc tcacatctgt gctcccagat    480

gccagcgtga cccctgacac gtgtgtgcag cagcctgcag ctgccccaag ccatggctga    540

acactgactc ccagctgtgg ggcttcacca ttacagactc cccagggctt caaagact      598


<210>  6315
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  6315

Met Arg Pro Ala Pro His Ser Val Pro Leu Cys Ala Thr Pro Cys Gln 
1               5                   10                  15


Ala Leu Arg Ala Pro Gly Cys Cys Phe Leu Pro Ser Phe Pro Lys Asp 
            20                  25                  30


Tyr Gln Arg Leu Pro Leu Ala Pro Leu Trp Ala Ser Ala Phe Leu Ser 
        35                  40                  45


Met Gln Trp Gly Phe Arg Ile Ala Val Val Ser Glu Ser Glu Ala Met 
    50                  55                  60


Arg Ser Glu Arg Ala Leu Val Trp Ser His Leu 
65                  70                  75


<210>  6316
<211>  1010
<212>  DNA
<213>  Homo sapiens

<400>  6316
tcactttcac actcccaggc tgtggctctt acccgtgccg agctttcaca tccgctcaca     60

tctgtgctcc cagatgccag cgtgacccct gacacgtgtg tgcagcagcc tgcagctgcc    120

ccaagccatg gctgaacact gactcccagc tgtggggctt caccattaca gactccccag    180

ggaaggggcc tggtgccgag gattccccac ccagcaagga gccctctcct ggccaggagc    240

ttcctccagg acaagacctt ccacccaaca aggactcccc ttctgggcag gaacccgctc    300

ccagccaaga accactgtcc agcaaagact cagctacctc tgaaggatcc cctccaggcc    360

cagatgctcc gcccagcaag gatgtgccac catgccagga accccctcca gcccaagacc    420

tctcaccctg ccaggaccta cctgctggtc aagaacccct gcctcaccag gaccctctac    480

tcaccaaaga cctccctgcc atccaggaat cccccacccg ggaccttcca ccctgtcaag    540

atctgcctcc tagccaggtc tccctgccag ccaaggccct tactgaggac accatgagct    600

ccggggacct actagcagct actggggacc cacctgcggc ccccaggcca gccttcgtga    660

tccctgaggt ccggctggat agcacctaca gccagaaggc aggggcagag cagggctgct    720

cgggagatga ggaggatgca gaagaggccg aggaggtgga ggagggggag gaaggggagg    780

aggacgagga tgaggacacc agcgatgaca actacggaga gcgcagtgag gccaagcgca    840

gcagcatgat cgagacgggc cagggggctg agggtggcct ctcactgcgt gtgcagaact    900

cgctgcggcg ccggacgcac agcgagggca gcctgctgca ggagccccga gggccctgct    960

ttgcctccga caccaccttg cactgctcag acggtgaggg cgccgcctcc              1010


<210>  6317
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  6317

Met Ser Ser Gly Asp Leu Leu Ala Ala Thr Gly Asp Pro Pro Ala Ala 
1               5                   10                  15


Pro Arg Pro Ala Phe Val Ile Pro Glu Val Arg Leu Asp Ser Thr Tyr 
            20                  25                  30


Ser Gln Lys Ala Gly Ala Glu Gln Gly Cys Ser Gly Asp Glu Glu Asp 
        35                  40                  45


Ala Glu Glu Ala Glu Glu Val Glu Glu Gly Glu Glu Gly Glu Glu Asp 
    50                  55                  60


Glu Asp Glu Asp Thr Ser Asp Asp Asn Tyr Gly Glu Arg Ser Glu Ala 
65                  70                  75                  80


Lys Arg Ser Ser Met Ile Glu Thr Gly Gln Gly Ala Glu Gly Gly Leu 
                85                  90                  95


Ser Leu Arg Val Gln Asn Ser Leu Arg Arg Arg Thr His Ser Glu Gly 
            100                 105                 110


Ser Leu Leu Gln Glu Pro Arg Gly Pro Cys Phe Ala Ser Asp Thr Thr 
        115                 120                 125


Leu His Cys Ser Asp Gly Glu Gly Ala Ala 
    130                 135


<210>  6318
<211>  1726
<212>  DNA
<213>  Homo sapiens

<400>  6318
atggtaacga ggaggccagt cacaaatagc tgggactggc ttcctgccgg ggcggcccca     60

gaggctgtcc cttgcagaca catgcccctt tcacggctcc ctctcagggt tggccagaag    120

gaattttttt ttccgctccc cctcctggtc cctcccattt cctggctcct cctgtctgag    180

tcccagcccc ggcttgtgcc tgggagtcca gtcatcaggc caggattcca gagagcgtgt    240

gtggctgcag cctgcaccgt tgctgcccgc tgcccaggac gcggggtggg ggacaggagc    300

cagagtggtg cctcctacag accaatctgc ggccccaagg tggggggccc tacagagatg    360

ctccgaggca tgtacctcac tcgcaacggg aacctgcaga ggcgacacac gatgaaggaa    420

gccaaggaca tgaagaacaa gctggggatc ttcagacggc ggaatgagtc ccctggagcc    480

cctcccgcgg gcaaggcaga caaaatgatg aagtcattca agcccacctc agaggaagcc    540

ctcaagtggg gcgagtcctt ggagaagctg ctggttcaca aatacgggtt agcagtgttc    600

caagccttcc ttcgcactga gttcagtgag gagaatctgg agttctggtt ggcttgtgag    660

gacttcaaga aggtcaagtc acagtccaag atggcatcca aggccaagaa gatctttgct    720

gaatacatcg cgatccaggc atgcaaggag gtcaacctgg actcctacac gcgggagcac    780

accaaggaca acctgcagag cgtcacgcgg ggctgcttcg acctggcaca gaagcgcatc    840

ttcgggctca tggaaaagga ctcgtaccct cgctttctcc gttctgacct ctacctggac    900

cttattaacc agaagaagat gagtcccccg ctttaggggc cactggagtc gagctcagcg    960

ttcacaccag gcgggctggg tcccctgccc acctgcctcc ctgccccctg tgacggaggg   1020

ggcaagcaag cccccagagg ctgtgtctct ggacagacgg atagacatac ggaagcgagg   1080

cctggaccaa gagaggccca ggctactgga ggagtagaag gatgggcccc gtggggtccc   1140

cactgccccg gtacgagggg gcccaagacc ctggcaggtc aggggccctg gccaagccag   1200

atctggagct gctgctccct gctgcggaga ccgcggaggc ttcgcgttga ccaagttcct   1260

taaagaactg gctgatgggg caggaggtcc aggcctgggc tctcgggccc tcctagaggg   1320

ccattggagc ttgcagctca gacccccact ttgagtttta tttatttaaa tagtagttgg   1380

atgcttggca cgtcgtcctg taataggaaa cccttgcctc atcagttttc ctgatttaca   1440

agtgcaatat tttagccaat gccttgggag aagctgccat gcaaaggtgg acaccattct   1500

ccagcttcag gggatatgct cgtcccgggc accggtggca ggcagctggc cttctggact   1560

aaggcagcct ggggggacac tgcagtctgg ctacacacag agatctggca ccccctgggt   1620

ggagtgtccc tcgggggctt tgggaaagca tggcaccctc agaccacaca gtagccaagt   1680

tctggagcaa ataaaaggcc tgtgttattt cttgttcttg accctt                  1726


<210>  6319
<211>  311
<212>  PRT
<213>  Homo sapiens

<400>  6319

Met Val Thr Arg Arg Pro Val Thr Asn Ser Trp Asp Trp Leu Pro Ala 
1               5                   10                  15


Gly Ala Ala Pro Glu Ala Val Pro Cys Arg His Met Pro Leu Ser Arg 
            20                  25                  30


Leu Pro Leu Arg Val Gly Gln Lys Glu Phe Phe Phe Pro Leu Pro Leu 
        35                  40                  45


Leu Val Pro Pro Ile Ser Trp Leu Leu Leu Ser Glu Ser Gln Pro Arg 
    50                  55                  60


Leu Val Pro Gly Ser Pro Val Ile Arg Pro Gly Phe Gln Arg Ala Cys 
65                  70                  75                  80


Val Ala Ala Ala Cys Thr Val Ala Ala Arg Cys Pro Gly Arg Gly Val 
                85                  90                  95


Gly Asp Arg Ser Gln Ser Gly Ala Ser Tyr Arg Pro Ile Cys Gly Pro 
            100                 105                 110


Lys Val Gly Gly Pro Thr Glu Met Leu Arg Gly Met Tyr Leu Thr Arg 
        115                 120                 125


Asn Gly Asn Leu Gln Arg Arg His Thr Met Lys Glu Ala Lys Asp Met 
    130                 135                 140


Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly Ala 
145                 150                 155                 160


Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro Thr 
                165                 170                 175


Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu Val 
            180                 185                 190


His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu Phe 
        195                 200                 205


Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys Lys 
    210                 215                 220


Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe Ala 
225                 230                 235                 240


Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr 
                245                 250                 255


Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly Cys 
            260                 265                 270


Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp Ser 
        275                 280                 285


Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln 
    290                 295                 300


Lys Lys Met Ser Pro Pro Leu 
305                 310


<210>  6320
<211>  730
<212>  DNA
<213>  Homo sapiens

<400>  6320
gaggccagtc acaaatagct gggactggct tcctgccggg gcggccccag aggctgtccc     60

ttgcagacac atgccccttt cacggctccc tctcagggtt ggccagaagg aatttttttt    120

tccgctcccc ctcctggtcc ctcccatttc ctggctcctc ctgtctgagt cccagccccg    180

gcttgtgcct gggagtccag tcatcaggcc aggattccag agagcgtgtg tggctgcagc    240

ctgcaccgtt gctgcccgct gcccaggacg cggggtgggg gacaggagcc agagtggtgc    300

ctcctacaga ccaatctgcg gccccaaggt ggggggccct acagagatgc tccgaggcat    360

gtacctcact cgcaacggga acctgcagag gcgacacacg atgaaggaag ccaaggacat    420

gaagaacaag ctggggatct tcagacggcg gaatgagtcc cctggagccc ctcccgcggg    480

caaggcagac aaaatgatga agtcattcaa gtaggtcctc cctggcaccc tgggaccctt    540

tggggaactc actggctccc cggggagtag gactgagtgg tagggttgag gggaaggggc    600

ttgccggctt gatccagctc tgggggagac aggctttcac agagggagct gggtacctgg    660

caagcagcta ccctcacagg gagcagctgc cctaggggga aggctaggtg gggtggagat    720

gggggctgga                                                           730


<210>  6321
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  6321

Met Pro Leu Ser Arg Leu Pro Leu Arg Val Gly Gln Lys Glu Phe Phe 
1               5                   10                  15


Phe Pro Leu Pro Leu Leu Val Pro Pro Ile Ser Trp Leu Leu Leu Ser 
            20                  25                  30


Glu Ser Gln Pro Arg Leu Val Pro Gly Ser Pro Val Ile Arg Pro Gly 
        35                  40                  45


Phe Gln Arg Ala Cys Val Ala Ala Ala Cys Thr Val Ala Ala Arg Cys 
    50                  55                  60


Pro Gly Arg Gly Val Gly Asp Arg Ser Gln Ser Gly Ala Ser Tyr Arg 
65                  70                  75                  80


Pro Ile Cys Gly Pro Lys Val Gly Gly Pro Thr Glu Met Leu Arg Gly 
                85                  90                  95


Met Tyr Leu Thr Arg Asn Gly Asn Leu Gln Arg Arg His Thr Met Lys 
            100                 105                 110


Glu Ala Lys Asp Met Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn 
        115                 120                 125


Glu Ser Pro Gly Ala Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys 
    130                 135                 140


Ser Phe Lys 
145


<210>  6322
<211>  777
<212>  DNA
<213>  Homo sapiens

<400>  6322
gaggccagtc acaaatagct gggactggct tcctgccggg gcggccccag aggctgtccc     60

ttgcagacac atgccccttt cacggctccc tctcagggtt ggccagaagg aatttttttt    120

tccgctcccc ctcctggtcc ctcccatttc ctggctcctc ctgtctgagt cccagccccg    180

gcttgtgcct gggagtccag tcatcaggcc aggattccag agagcgtgtg tggctgcagc    240

ctgcaccgtt gctgcccgct gcccaggacg cggggtgggg gacaggagcc agagtggtgc    300

ctcctacaga ccaatctgcg gccccaaggt ggggggccct acagagatgc tccgaggcat    360

gtacctcact cgcaacggga acctgcagag gcgacacacg atgaaggagt aggtgccctc    420

gacccagctc tcccgactct ggatttgcag gggcgagtgg gccaggctga gcaaccctct    480

tttctgcttc tgtccccaga gccaaggaca tgaagaacaa gctggggatc ttcagacggc    540

ggaatgagtc ccctggagcc cctcccgcgg gcaaggcaga caaaatgatg aagtcattca    600

agcccacctc agaggaagcc ctcaagtggg gcgagtcctt ggagaagctg ctggttcaca    660

aatgtaagtt gggcctgcct gcccactccc tgtgccctct ctccctctcc ccttcgcccc    720

catccagacc ctgtgtagct ggtgctagag aggccgcctt ccctctcctc ggccgtc       777


<210>  6323
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  6323

Met Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly 
1               5                   10                  15


Ala Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro 
            20                  25                  30


Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu 
        35                  40                  45


Val His Lys Cys Lys Leu Gly Leu Pro Ala His Ser Leu Cys Pro Leu 
    50                  55                  60


Ser Leu Ser Pro Ser Pro Pro Ser Arg Pro Cys Val Ala Gly Ala Arg 
65                  70                  75                  80


Glu Ala Ala Phe Pro Leu Leu Gly 
                85


<210>  6324
<211>  1665
<212>  DNA
<213>  Homo sapiens

<400>  6324
gaggccagtc acaaatagct gggactggct tcctgccggg gcggccccag aggctgtccc     60

ttgcagacac atgccccttt cacggctccc tctcagggtt ggccagaagg aatttttttt    120

tccgctcccc ctcctggtcc ctcccatttc ctggctcctc ctgtctgagt cccagccccg    180

gcttgtgcct gggagtccag tcatcaggcc aggattccag agagcgtgtg tggctgcagc    240

ctgcaccgtt gctgcccgct gcccaggacg cggggtgggg gacaggagcc agagtggtgc    300

ctcctacaga ccaatctgcg gccccaaggt ggggggccct acagagatgc tccgaggcat    360

ccaaggacat gaagaacaag ctggggatct tcagacggcg gaatgagtcc cctggagccc    420

ctcccgcggg caaggcagac aaaatgatga agtcattcaa gcccacctca gaggaagccc    480

tcaagtgggg cgagtccttg gagaagctgc tggttcacaa atacgggtta gcagtgttcc    540

aagccttcct tcgcactgag ttcagtgagg agaatctgga gttctggttg gcttgtgagg    600

acttcaagaa ggtcaagtca cagtccaaga tggcatccaa ggccaagaag atctttgctg    660

aatacatcgc gatccaggca tgcaaggagg tcaacctgga ctcctacacg cgggagcaca    720

ccaaggacaa cctgcagagc gtcacgcggg gctgcttcga cctggcacag aagcgcatct    780

tcgggctcat ggaaaaggac tcgtaccctc gctttctccg ttctgacctc tacctggacc    840

ttattaacca gaagaagatg agtcccccgc tttaggggcc actggagtcg agctcagcgt    900

tcacaccagg cgggctgggt cccctgccca cctgcctccc tgccccctgt gacggagggg    960

gcaagcaagc ccccagaggc tgtgtctctg gacagacgga tagacatacg gaagcgaggc   1020

ctggaccaag agaggcccag gctactggag gagtagaagg atgggccccg tggggtcccc   1080

actgccccgg tacgaggggg cccaagaccc tggcaggtca ggggccctgg ccaagccaga   1140

tctggagctg ctgctccctg ctgcggagac cgcggaggct tcgcgttgac caagttcctt   1200

aaagaactgg ctgatggggc aggaggtcca ggcctgggct ctcgggccct cctagagggc   1260

cattggagct tgcagctcag acccccactt tgagttttat ttatttaaat agtagttgga   1320

tgcttggcac gtcgtcctgt aataggaaac ccttgcctca tcagttttcc tgatttacaa   1380

gtgcaatatt ttagccaatg ccttgggaga agctgccatg caaaggtgga caccattctc   1440

cagcttcagg ggatatgctc gtcccgggca ccggtggcag gcagctggcc ttctggacta   1500

aggcagcctg gggggacact gcagtctggc tacacacaga gatctggcac cccctgggtg   1560

gagtgtccct cgggggcttt gggaaagcat ggcaccctca gaccacacag tagccaagtt   1620

ctggagcaaa taaaaggcct gtgttatttc ttgttcttga ccctt                   1665


<210>  6325
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  6325

Met Lys Asn Lys Leu Gly Ile Phe Arg Arg Arg Asn Glu Ser Pro Gly 
1               5                   10                  15


Ala Pro Pro Ala Gly Lys Ala Asp Lys Met Met Lys Ser Phe Lys Pro 
            20                  25                  30


Thr Ser Glu Glu Ala Leu Lys Trp Gly Glu Ser Leu Glu Lys Leu Leu 
        35                  40                  45


Val His Lys Tyr Gly Leu Ala Val Phe Gln Ala Phe Leu Arg Thr Glu 
    50                  55                  60


Phe Ser Glu Glu Asn Leu Glu Phe Trp Leu Ala Cys Glu Asp Phe Lys 
65                  70                  75                  80


Lys Val Lys Ser Gln Ser Lys Met Ala Ser Lys Ala Lys Lys Ile Phe 
                85                  90                  95


Ala Glu Tyr Ile Ala Ile Gln Ala Cys Lys Glu Val Asn Leu Asp Ser 
            100                 105                 110


Tyr Thr Arg Glu His Thr Lys Asp Asn Leu Gln Ser Val Thr Arg Gly 
        115                 120                 125


Cys Phe Asp Leu Ala Gln Lys Arg Ile Phe Gly Leu Met Glu Lys Asp 
    130                 135                 140


Ser Tyr Pro Arg Phe Leu Arg Ser Asp Leu Tyr Leu Asp Leu Ile Asn 
145                 150                 155                 160


Gln Lys Lys Met Ser Pro Pro Leu 
                165


<210>  6326
<211>  1270
<212>  DNA
<213>  Homo sapiens

<400>  6326
cggggacggg cattgtactc agctcccagc acgcccatct ttaaagtcct gtaggggtaa     60

gctgaggcat cttaagggca ggagaggctg agtttgcctc ttaccccagg atccgttctc    120

ctcacagacg ggttagcagt gttccaagcc ttccttcgca ctgagttcag tgaggagaat    180

ctggagttct ggttggcttg tgaggacttc aagaaggtca agtcacagtc caagatggca    240

tccaaggcca agaagatctt tgctgaatac atcgcgatcc aggcatgcaa ggaggtcaac    300

ctggactcct acacgcggga gcacaccaag gacaacctgc agagcgtcac gcggggctgc    360

ttcgacctgg cacagaagcg catcttcggg ctcatggaaa aggactcgta ccctcgcttt    420

ctccgttctg acctctacct ggaccttatt aaccagaaga agatgagtcc cccgctttag    480

gggccactgg agtcgagctc agcgttcaca ccaggcgggc tgggtcccct gcccacctgc    540

ctccctgccc cctgtgacgg agggggcaag caagccccca gaggctgtgt ctctggacag    600

acggatagac atacggaagc gaggcctgga ccaagagagg cccaggctac tggaggagta    660

gaaggatggg ccccgtgggg tccccactgc cccggtacga gggggcccaa gaccctggca    720

ggtcaggggc cctggccaag ccagatctgg agctgctgct ccctgctgcg gagaccgcgg    780

aggcttcgcg ttgaccaagt tccttaaaga actggctgat ggggcaggag gtccaggcct    840

gggctctcgg gccctcctag agggccattg gagcttgcag ctcagacccc cactttgagt    900

tttatttatt taaatagtag ttggatgctt ggcacgtcgt cctgtaatag gaaacccttg    960

cctcatcagt tttcctgatt tacaagtgca atattttagc caatgccttg ggagaagctg   1020

ccatgcaaag gtggacacca ttctccagct tcaggggata tgctcgtccc gggcaccggt   1080

ggcaggcagc tggccttctg gactaaggca gcctgggggg acactgcagt ctggctacac   1140

acagagatct ggcaccccct gggtggagtg tccctcgggg gctttgggaa agcatggcac   1200

cctcagacca cacagtagcc aagttctgga gcaaataaaa ggcctgtgtt atttcttgtt   1260

cttgaccctt                                                          1270


<210>  6327
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  6327

Met Ala Ser Lys Ala Lys Lys Ile Phe Ala Glu Tyr Ile Ala Ile Gln 
1               5                   10                  15


Ala Cys Lys Glu Val Asn Leu Asp Ser Tyr Thr Arg Glu His Thr Lys 
            20                  25                  30


Asp Asn Leu Gln Ser Val Thr Arg Gly Cys Phe Asp Leu Ala Gln Lys 
        35                  40                  45


Arg Ile Phe Gly Leu Met Glu Lys Asp Ser Tyr Pro Arg Phe Leu Arg 
    50                  55                  60


Ser Asp Leu Tyr Leu Asp Leu Ile Asn Gln Lys Lys Met Ser Pro Pro 
65                  70                  75                  80


Leu 



<210>  6328
<211>  3043
<212>  DNA
<213>  Homo sapiens

<400>  6328
ctgtgggcca gaggagagca ctgggtacca gaatcacaga tcaggagctg tggaaggcgc     60

tgcccgacag gatgggggac cctgggagag ggatgcagcc acatccaaac tgtggcccag    120

aagagggagt gggaaaagtc ctcgacctct ctgtcttcct gctgtcttcc aatatcctac    180

ctggaaagca acgggtctga aaggtaattc tgttcttgat gagggtgcag gcagcagagg    240

gaattgtcat cctgctgaag acacacagct cttccatgct ctaccctatg tgtaatttgt    300

tcttatctgc tcctggagcc accacctgct acagtgtaaa gagaccccac agactctctg    360

gatcaaacta ctcactgtcc agaaggagaa aatgaggtcc tatgtctgtg gctagaaccc    420

aggcctctgg ggagcaaccc agggctccat ccagggtgac ctgagcctgc tctgctcatc    480

agagccagtc tttaccaccc ttcatatccc gggagcccac aggtagaaag atgggcattg    540

caggtcaccg tggttccccc actgaagcaa gttccctggc tcgcgattag ccagtgctct    600

gctggttcat gatgcgctcc aaatgctaga ccaagaaaga aactgggtcg gtgggcagga    660

cacaggacca gcgctctggg aggagagctg ttctcaagca gtttggtggc atcagagcct    720

ctgtgtggtc agtcaagcag ggcagccaat ttcctctcct ttcagcccta actctggact    780

cctgtacctg gaggggctcc ctttgtgctc ctgcagccca gaagccctcc gaggcttgac    840

atgaaagagt cgcgggatct tggactgttc cggtggaagg gctcctagca aaacccagat    900

gttttctctt cttgtatgga tgggaggacc gaagtccaga gaagtggaat aacttgccca    960

gggttgtgct gagatttgtg aaggtgccgg atgctggtgt gctggtggct ggcatgctct   1020

gagcccttcc ttcccgctgt ttccctggag ttctgcttgg caaccacccg cctgcatttt   1080

tgcaaagtga tgtcatctgc agataatggt ttttccgttc ctggtggagc aggagttcca   1140

gatacagtgc ttcgggggag gggctcaaga gagctgattg tgcactcctc aggcaagtgg   1200

gggctgcata gaccccctcc cctctgacag tcacatctca gttgtaaggc aaggcaccgt   1260

ctcaggcttc ctggactccg gaacctggaa tgaccaaaat ggcagaggcc ccagagacaa   1320

gcctcccctg cctcctcctt gtagagttgg gaatctgagg cccagagagg gcagagcctt   1380

gcccaagctc acacagcatt tacaggcaaa accttgactc acatcccgac tcctaacatc   1440

tgtggccact tgcccgtggt tgggggtttt tcaccctcaa caccgttgac attttgggcc   1500

aaggagtttt gttgtggggg cagtcccttt catggcagga tgtttggcag catccctggc   1560

ctcgacctcc tacaggccag tagcacccct ctccagttct caaatccaga cactgccaaa   1620

tgtctttcac ctaagttggg gtgggagaaa gtaaccctcc agctcctaag acctttatcc   1680

actgccatag gcaggagagg tttcttgagt ccaagcccaa agggtgcttt gtctgaggct   1740

ctgacttaac gtcaggcacc ttcaggatgg gaggcaggcc tggagggggc tatgaggggc   1800

tggagatggt ccaggccctc cttctggtta ggaacactgc ttcctctgat cacttttctt   1860

ggagcaaaac tgccgattta ttttcctggg gaaataaaaa taaatgctgg ctgttgtaat   1920

ctcatccctg atcccatctg gaaaaagcag gctcatgaat cttggccgcc tgagctctga   1980

ggactgtgtc tggcggaacc tggagttaca atgggccttc gaacatcgga acagtcacgg   2040

ctgacatttc ctttcccgtt acatggctcc ttggaatgtg agccccaggg ggccgtccgt   2100

gggcaggcgg aatttggtgg aaagaagtgc tgcacgggcc ggaggccagc tcagcttctg   2160

acttgctgtg tgactttggg ccacttttct gttcgtttct gggccttgat ttctccatct   2220

gcagaatgag gggagccacg ttcctcaaca aggggtccat ggaccacctt gtatcagaac   2280

catttaggga atgtgtttat ggctattcct gatatttctg attcctcttc cagacctcct   2340

aaagttttta tgcatctcta agtgatttcg atatatataa gttttgggac ccacaacacc   2400

aaggactttg aactttccac ccagtttcaa gtttgaacac atcacagttc ttcagcctcc   2460

ttccccctca taacgaagtg tagagttatg aagctagagg gtaaaattat ggggtgggct   2520

ggaactgggc attgctccta acaattatct gctttcaaac tcttggcagg gtctctgggg   2580

tccttgatcc aactgaaatc actgttaaag cactttattc ctccagtaat gaaactcgag   2640

ctgctagtta cagagtttgg tttcaaaatt gtgccattta ttatttttgt tggattggct   2700

tataaaccct catatagtca tacatcattt ataatgcatt attccatgag aatgcatttt   2760

ccagatgaga tttatttttt ctgttaaaaa cttaaaactg ttcttttttt ttttttaaat   2820

ggcagtcttt cgccatgtgt tacctattta taccacctta agtgaaggtc aggaaatgca   2880

attttactta ttctcaatgc tccagggttg tcattgtgag ttttaactac tgtatgcatt   2940

gatgtaaatt ttagggactc caaaactcac tgtgcctgaa ctatgaatgt cccccaagct   3000

gcttagccct tgtgtctgct tttaaaagtt ctgctttgct tct                     3043


<210>  6329
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  6329

Met Gly Asp Pro Gly Arg Gly Met Gln Pro His Pro Asn Cys Gly Pro 
1               5                   10                  15


Glu Glu Gly Val Gly Lys Val Leu Asp Leu Ser Val Phe Leu Leu Ser 
            20                  25                  30


Ser Asn Ile Leu Pro Gly Lys Gln Arg Val 
        35                  40


<210>  6330
<211>  1221
<212>  DNA
<213>  Homo sapiens

<400>  6330
gaagactcac tggtccagaa gtcagaacac ctgagtcact tgacatgcac tctcagatga     60

gctgctgcac tgctctgtgc ctcagccgct ttcatctgta gaatgggatg gtcatgatgc    120

ctggccagca gggcccatgg agcttgtata aaacctgatg ggaggggagg ttgcagtaaa    180

agccttggag atgaaaacac tggacacagg tcccctggag tcattggaat gcaggttcct    240

actcggaggc ctgggtttcc aacaatctcc cagttcctag gcccagatgt ccaccctcct    300

tcacgagctc agaattgagc tcgtatcgcc aacatgtttt gcggaaatgc tcatatcaac    360

acttggtgaa ccaggaagac tgtaccctca ttcctttctc ctgctgcctg ctaggttgag    420

ttagaaagct tactctcgag ttttactggc ttgcttgtgc tttttggcat tttcaaaatt    480

ttgtacaatg atcttcaaaa agcaaaaata cattaatttt tttaaaggta ggatccatat    540

gagattggat cttcatcttc taacactttg gagaacagaa aagtggtatt tggagatata    600

atcttcataa gaattgtggc actgaataaa agagcactgg aagaggaaag aaacataaag    660

gaaagaaagg aaaagaaaag accaaaagaa aagcaaggct ccacttgcaa atgagagagc    720

aacttggaaa acctgccact cactaccact gatgcccaca agagggcgtc tcagggtcat    780

ccggaaggca aaactcaagt ccaagatccg cttcccagca gctggaaatg accaatgagt    840

aggttctgga atatcagcaa tgaccctggc tctccagcac tttacagttt acattagact    900

ctcctccccg acgtcatttg cacctcccaa ggccagttct cccggtggtt tccagccctg    960

gggcgtttgt ggttctctct gcctagtggg atgcaactgg catttagtgt ttgtccgtat   1020

gtgggtgtgg ctggggaggg cagagaggca aacagccccg cacaagctgt acagtccccc   1080

tcatcaagat gtggcactcc ctctttgcca atagcaactc ctttttgaaa cactgggcct   1140

gaagcaatca tcttgaagac atttttcatc aatcttgttg aaatcaacct ggtttttcaa   1200

aatagaggaa gcacatcaat g                                             1221


<210>  6331
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  6331

Met Gly Gly Glu Val Ala Val Lys Ala Leu Glu Met Lys Thr Leu Asp 
1               5                   10                  15


Thr Gly Pro Leu Glu Ser Leu Glu Cys Arg Phe Leu Leu Gly Gly Leu 
            20                  25                  30


Gly Phe Gln Gln Ser Pro Ser Ser 
        35                  40


<210>  6332
<211>  8884
<212>  DNA
<213>  Homo sapiens

<400>  6332
cgcaaaaaat aaataaatta gagcatcttt tggggggagg gaattcagcg gatcagtctt     60

aagaggagct tttttttgga gcgagaaatc atataaaata aaatgaaata aaacaaggag    120

gaaggcaacc agctgttagg ggaaaaataa ggcagataaa ggagcgggga gagaaattaa    180

ttgccaacca ggaggagttg ggctgtattt ttcaaaggtg gggagagtgg agcacacacc    240

ttgaggagga aagcgagaaa gaaaagaaaa aagcaagtgg aaaggggggc tcgcccaaga    300

agggtgaaga agcgaagaaa gtcgaggcgc cgaggctccc aaagctggca gctccgggtg    360

gcggtgcagg ggcgaagggg gggcgggggg aaccgtcgga catgcggctc tggagttggg    420

tgctgcacct ggggctgctg agcgccgcgc tgggctgcgg gctggccgag cgtccccgcc    480

gggcccggag agacccgcgg gccggccgac ccccgcgccc cgccgccggc ccggccacct    540

gcgccacccg ggcggcccgc ggccgccgcg cctcgccgcc gccgccgccg ccgccgggcg    600

gtgcctggga agccgtgcgc gtcccccggc ggcggcagca gcgggaggcg aggggcgcca    660

ccgaggagcc gagcccgccg agccgggcgc tctatttcag cgggcgaggc gagcagctgc    720

gcctccgggc cgacctcgag ctgccccggg acgcgttcac gctgcaagtg tggctgcgag    780

cggagggggg ccagaggtct ccggcagtga tcacagggct gtatgacaaa tgttcttata    840

tctcacgtga ccgaggatgg gtcgtgggca ttcacaccat cagtgaccaa gacaacaaag    900

acccacgcta ctttttctcc ttgaagacag accgagcccg gcaagtgacc accatcaatg    960

cccaccgcag ctacctccca ggccagtggg tatacctagc tgccacctat gatgggcagt   1020

tcatgaagct ctatgtgaat ggtgcccagg tggccacctc tggggaacaa gtgggtggca   1080

tattcagccc actgacccag aagtgcaaag tgctcatgtt agggggcagt gccctgaatc   1140

acaactaccg gggctacatc gagcacttca gtctgtggaa ggtggccagg actcagcggg   1200

agatactgtc tgacatggaa acccatggcg cccacactgc tctacctcag ctcctcctcc   1260

aggagaactg ggacaatgtg aagcatgcct ggtcccccat gaaggatggc agcagcccca   1320

aagtggaatt cagcaatgcc cacggctttc tgctggacac gagtctggag cctcctctgt   1380

gcggacagac attgtgtgac aacacagagg tcattgccag ctacaatcag ctctcaagtt   1440

tccgccagcc caaggtggtg cgctaccgcg tggtcaacct ctatgaagat gatcataaga   1500

acccgacggt gacgcgcgag caggtggact tccagcacca tcagctggct gaggccttca   1560

agcaatacaa catctcctgg gagctggacg tgctggaggt gagcaactcc tcccttcgcc   1620

gccgcctcat cctggccaac tgtgacatca gcaagattgg ggatgagaac tgtgaccccg   1680

agtgcaacca cacgctgacg ggccacgacg gcggggattg ccgccacctg cgccaccctg   1740

ccttcgtgaa gaagcagcac aacggggtgt gtgacatgga ctgcaactat gaacggttca   1800

actttgatgg tggagagtgc tgtgaccctg aaatcaccaa tgtcactcag acttgctttg   1860

accccgactc tccacacaga gcctacttgg atgttaatga gctgaagaac attcttaaat   1920

tggatggatc aacacatctc aatattttct ttgcaaaatc ctcagaggag gagttggcag   1980

gagtagcaac ttggccatgg gacaaggagg ccctgatgca cttaggtggc attgtcttga   2040

acccatcttt ctatggcatg cctgggcaca cccacaccat gatccatgag attggtcaca   2100

gcctgggcct ctatcacgtc ttccgaggca tctcagaaat ccagtcctgc agtgacccct   2160

gcatggagac agagccctcc ttcgagactg gagacctctg caatgatacc aacccagccc   2220

ctaaacacaa gtcctgtggt gacccagggc caggaaatga cacctgtggc tttcatagct   2280

tcttcaacac tccttacaac aacttcatga gctatgcaga tgacgactgt acggactcct   2340

tcacgcccaa tcaagtcgcc agaatgcact gttacctgga cctggtctac cagggctggc   2400

agccctccag gaaaccagcg cctgttgccc tcgcccccca agttctgggc cacacaacgg   2460

actctgtgac actggagtgg ttcccaccta tagatggcca tttctttgaa agagaattgg   2520

gatcagcatg tcatctttgc ctggaaggga gaatcctggt gcagtatgct tccaacgctt   2580

cctccccaat gccctgcagc ccatcaggac actggagccc tcgtgaagca gaaggtcatc   2640

ctgatgttga acagccctgt aagtccagtg tccgcacctg gagcccaaat tcagctgtca   2700

acccacacac ggttcctcca gcctgccctg agcctcaagg ctgctacctc gagctggagt   2760

tcctctaccc cttggtccct gagtctctga ccatttgggt gacctttgtc tccactgact   2820

gggactctag tggagctgtc aatgacatca aactgttggc tgtcagtggg aagaacatct   2880

ccctgggtcc tcagaatgtc ttctgtgatg tcccactgac catcagactc tgggacgtgg   2940

gcgaggaggt gtatggcatc caaatctaca cgctggatga gcacctggag atcgatgctg   3000

ccatgttgac ctccactgca gacaccccac tctgtctaca gtgtaagccc ctgaagtata   3060

aggtggtccg ggaccctcct ctccagatgg atgtggcctc catcctacat ctcaatagga   3120

aattcgtaga catggatcta aatcttggca gtgtgtacca gtattgggtc ataactattt   3180

caggaactga agagagtgag ccatcacctg ctgtcacata catccatgga agtgggtact   3240

gtggcgatgg cattatacaa aaagaccaag gtgaacaatg cgacgacatg aataagatca   3300

atggtgatgg ctgctccctt ttctgccgac aagaagtctc cttcaattgt attgatgaac   3360

ccagccggtg ctatttccat gatggtgatg gggtatgtga ggagtttgaa caaaaaacca   3420

gcattaagga ctgtggtgtc tacacgcccc agggattcct ggatcagtgg gcatccaatg   3480

cttcagtatc tcatcaagac cagcaatgcc caggctgggt catcatcgga cagccagcag   3540

catcccaggt gtgtcgaacc aaggtgatag atctcagtga aggcatttcc cagcatgcct   3600

ggtacccttg caccatcagc tacccatatt cccagctggc tcagaccact ttttggctcc   3660

gggcgtattt ttctcaacca atggttgccg cagctgtcat tgtccacctg gtgacggatg   3720

ggacatatta tggggaccaa aagcaggaga ccatcagcgt gcagctgctt gataccaaag   3780

atcagagcca cgatctaggc ctccatgtcc tgagctgcag gaacaatccc ctgattatcc   3840

ctgtggtcca tgacctcagc cagcccttct accacagcca ggcggtacgt gtgagcttca   3900

gttcgcccct ggtcgccatc tcgggggtgg ccctccgttc cttcgacaac tttgaccccg   3960

tcaccctgag cagctgccag agaggggaga cctacagccc tgccgagcag agctgcgtgc   4020

acttcgcatg tgagaaaact gactgtccag agctggctgt ggagaatgct tctctcaatt   4080

gctccagcag cgaccgctac cacggtgccc agtgtactgt gagctgccgg acaggctacg   4140

tgctccagat acggcgggat gatgagctga tcaagagcca gacgggaccc agcgtcacag   4200

tgacctgtac agagggcaag tggaataagc aggtggcctg tgagccagtc gactgcagca   4260

tcccagatca ccatcaagtc tatgctgcct ccttctcctg ccctgagggc accacctttg   4320

gcagtcaatg ttccttccag tgccgtcacc ctgcacaatt gaaaggcaac aacagcctcc   4380

tgacctgcat ggaggatggg ctgtggtcct tcccagaggc cctgtgtgag ctcatgtgcc   4440

tcgctccacc ccctgtgccc aatgcagacc tccagaccgc ccggtgccga gagaataagc   4500

acaaggtggg ctccttctgc aaatacaaat gcaagcctgg ataccatgtg cctggatcct   4560

ctcggaagtc aaagaaacgg gccttcaaga ctcagtgtac ccaggatggc agctggcagg   4620

agggagcttg tgttcctgtg acctgtgacc cacctccacc aaaattccat gggctctacc   4680

agtgtactaa tggcttccag ttcaacagtg agtgtaggat caagtgtgaa gacagtgatg   4740

cctcccaggg acttgggagc aatgtcattc attgccggaa agatggcacc tggaacggct   4800

ccttccatgt ctgccaggag atgcaaggcc agtgctcggt tccaaacgag ctcaacagca   4860

acctcaaact gcagtgccct gatggctatg ccatagggtc ggagtgtgcc acctcgtgcc   4920

tggaccacaa cagcgagtcc atcatcctgc caatgaacgt gaccgtgcgt gacatccccc   4980

actggctgaa ccccacacgg gtagagagag ttgtctgcac tgctggtctc aagtggtatc   5040

ctcaccctgc tctgattcac tgtgtcaaag gctgtgagcc cttcatggga gacaattatt   5100

gtgatgccat caacaaccga gccttttgca actatgacgg tggggattgc tgcacctcca   5160

cagtgaagac caaaaaggtc accccattcc ctatgtcctg tgatctacaa ggtgactgtg   5220

cttgtcggga cccccaggcc caagaacaca gccggaaaga cctccgggga tacagccatg   5280

gctaaggaag gacaagaagt tgtcaaagaa ttcccaacgc caggacccac atccctttgg   5340

tattgatttc acagtcagct gctcaacgga atggcctctc cacaccaggg atccttagca   5400

cccaaccggt ctgcctttaa ttttacccag gaaggactca cattggggcg aatgaaccaa   5460

gtttcgccat gctggatgat gaaatggatt cccatcccaa agtctgagat ggattgcata   5520

tacagtgtgc agtcccagag cctcctaaaa ttctagccat ttgtcacaca accacagcaa   5580

gaaacgtgtt ctatatctag agtgtgccca tctgtgttta gtacacatgc atgcatacac   5640

acccatacaa acatctgtgt gagggcagtt ctggagatga gcagagagag accggaataa   5700

actcaatctt ttctttccca agctcctagc caacactatc cttgggagaa agaaatttgc   5760

agaaactgct aagaccaagt gtggagatgt caagctagtt cacactctga ggctcagaat   5820

atgtaggaca tgcacaattg tgcagtcctt tgggattgga agtgaaacag tctgtgatcc   5880

cctaccttct agggaactag gacctaggaa gaggtaaaga ttatcaggta tgcaaagcgc   5940

cccaattctt ctgctgccat gggggatttt accccaactc cagggttcga ggccaatctg   6000

agaatggctt aggattgcaa tgtcaaggta ttatatcagc cccttgcttg aggcttgagg   6060

tcataatatc cctctaggac ttacctgttc ccccagatct tgccttggga ccacatttgc   6120

tgctactttt cctgctgctc tatcctatac attgaataat ccaagatggt agaactaggt   6180

taggaaaaat tccacacaac caaacagtct gccttaaaag tgacccacat ttttccatag   6240

ctcctcactt tttagccctt ctgcaagaga aaaaccctca tgggtccaca tggtgagaag   6300

ttaagtttcc tgtaagtggg cctctcaccc tggaaaggag ttgagggaca tcagatgctg   6360

gaaccctcac tgaaagtcca gaatgtctaa gccagtgtta gattttgtaa acaagtggaa   6420

cagtgttaaa tttctatgat gttggagcca tccagagact actggaattg tcgagacttt   6480

tggattatta tccttatcct tatcctaatc ttcctagccc ttcaggctag agtaggcttt   6540

gatcctgaga accttgctgt tgctctgagg agatataatt ctgggagaaa gaatctttta   6600

taagaacagt acagattgtt ctcaagaggg ccatcagaag gaagccaaag agttcacagc   6660

ctcagcacca acaactcaac atggtcatca tgttttctat atggtttttc cagctagcag   6720

tactcccttc catacctgtg actgggcagt gcttttctct ctcccatgtc tagcctccaa   6780

aagttaagtg aaaattagtc aactgcacgt ggaagccccc accactttgg ggatctcttt   6840

atttcttttc agccagggac ctgtccactc cctttgaatt aatatgggaa gaaattaata   6900

caggatgaac tggagagaag ggttgagtgt ggcatacttt ctgaaacctg gagctgggaa   6960

ttgcggagaa gggaaggtct agactagtta catcacatag ggattactgt aaatcaagtc   7020

atctcaagtc tagtgaagac agccaacaga aacaaaacct agcataggga tagaaaatac   7080

catgcacgtg tgcagcccca cctaattcct gcatccaagg caggtgttgt taatctatca   7140

tagcacttaa aaaaaaaaaa aaaaagagac caaaaataac tttaggaacc accatattat   7200

atcactccca atagcactga cctggtgatc aaaaacactt gagaagacat ctattggcca   7260

tctctggcca attacactaa gaaacatatc aaggtgcttt tggcacaggt gcccacaaat   7320

acggatgcag tgctgagata gtttatgaga cttgtaccat ttcacaaact ctgaaattgg   7380

gttccatatt ggcaaggctg ccacagttgt taagaataat cctctatgtt tcttcctcac   7440

aaaaccatat ctcatttata tccagaccat tacttcacta taattacaag gacaaattat   7500

tagcaagaaa taagaatagt attagaagaa ttgatcctat tttgaacccc tctccagtat   7560

cttcacactc ttgtcaactc tccaggcctc tctcttgccc tgagttatca gcctgtgtgg   7620

tgttaactac cttagaaggt acaagctaag aaatgtaaca gtatcaaccc tcccagttgc   7680

ttaattatac ccataggtaa tacaaaaagc tctgaagacc caaagatgac attactaatg   7740

atgtgatttc aggagccaca gaagaacctt accagcttcc ctcaaatcag tccttatcct   7800

ctttctatct tcactcccat catcatctat tttcacacta tccagctaag caaagattcc   7860

tggaggctga cttgtatctt cagactcaca gagtgaattc agctcttctg aatcaagacc   7920

cacccagtct ctttcattca gacctgttgc taacaaattt atatttgcca aggatattag   7980

gcaaaagagg ctacttgatt ggtggccaac ctcgtgccca catggaaggt atctttaata   8040

gggtcttttc aaaccttagt ggaggagggt cagctcaatt tgggcaatgc atttgttccc   8100

agtttcattt tcttcctggg aattaactcg tcatttcatt ccttcagtca tcttctgtgt   8160

aggtgaccgg agcactgaga ggcagctctg atgcactatt gtgtgtcagc agctcaaagg   8220

ccctaaaaca ctgaaggttc tgcatctgaa gtattagatt gttagcagca aaatatgaaa   8280

gatgaggtgg acagtcctct aagccctatt tagggaagct tttccaagcc acaatcttaa   8340

ctacctaccc aaaggatttg cattaccccc agattctgtg ccaacaacct tttaaggaaa   8400

tacagtcctt gggaaatgag ttttgatggt gaattggggt gttaaggaag ggaaagattg   8460

tcatagatgg tagggctttg aaaatgcagg gtatcagctg ccactcctgg cttcaacaca   8520

ttgagtcact gcctagacgg ttctcttggt cttattccca tcctggccaa tgcttaaata   8580

ctatttgttg aaaataattc tttgagacag atttcagcta cctcccttcc aggttcgatt   8640

taacttggtt gtaattgtca atttgttgtt ataggtctta cctgtgtgaa agaaagaaaa   8700

agaaagaaag aaagaaagag aaaggaaatt ataaggtcaa gttaacagtt ttgaggtttt   8760

gtgttttttt ctggaactac ttcaagtgag aaaataaaaa aaaatggtga caaagctgta   8820

cagatagaga taatagaaga caaagagatt aaaaggaaat aaaaatgcat gattaaaaac   8880

taag                                                                8884


<210>  6333
<211>  1627
<212>  PRT
<213>  Homo sapiens

<400>  6333

Met Arg Leu Trp Ser Trp Val Leu His Leu Gly Leu Leu Ser Ala Ala 
1               5                   10                  15


Leu Gly Cys Gly Leu Ala Glu Arg Pro Arg Arg Ala Arg Arg Asp Pro 
            20                  25                  30


Arg Ala Gly Arg Pro Pro Arg Pro Ala Ala Gly Pro Ala Thr Cys Ala 
        35                  40                  45


Thr Arg Ala Ala Arg Gly Arg Arg Ala Ser Pro Pro Pro Pro Pro Pro 
    50                  55                  60


Pro Gly Gly Ala Trp Glu Ala Val Arg Val Pro Arg Arg Arg Gln Gln 
65                  70                  75                  80


Arg Glu Ala Arg Gly Ala Thr Glu Glu Pro Ser Pro Pro Ser Arg Ala 
                85                  90                  95


Leu Tyr Phe Ser Gly Arg Gly Glu Gln Leu Arg Leu Arg Ala Asp Leu 
            100                 105                 110


Glu Leu Pro Arg Asp Ala Phe Thr Leu Gln Val Trp Leu Arg Ala Glu 
        115                 120                 125


Gly Gly Gln Arg Ser Pro Ala Val Ile Thr Gly Leu Tyr Asp Lys Cys 
    130                 135                 140


Ser Tyr Ile Ser Arg Asp Arg Gly Trp Val Val Gly Ile His Thr Ile 
145                 150                 155                 160


Ser Asp Gln Asp Asn Lys Asp Pro Arg Tyr Phe Phe Ser Leu Lys Thr 
                165                 170                 175


Asp Arg Ala Arg Gln Val Thr Thr Ile Asn Ala His Arg Ser Tyr Leu 
            180                 185                 190


Pro Gly Gln Trp Val Tyr Leu Ala Ala Thr Tyr Asp Gly Gln Phe Met 
        195                 200                 205


Lys Leu Tyr Val Asn Gly Ala Gln Val Ala Thr Ser Gly Glu Gln Val 
    210                 215                 220


Gly Gly Ile Phe Ser Pro Leu Thr Gln Lys Cys Lys Val Leu Met Leu 
225                 230                 235                 240


Gly Gly Ser Ala Leu Asn His Asn Tyr Arg Gly Tyr Ile Glu His Phe 
                245                 250                 255


Ser Leu Trp Lys Val Ala Arg Thr Gln Arg Glu Ile Leu Ser Asp Met 
            260                 265                 270


Glu Thr His Gly Ala His Thr Ala Leu Pro Gln Leu Leu Leu Gln Glu 
        275                 280                 285


Asn Trp Asp Asn Val Lys His Ala Trp Ser Pro Met Lys Asp Gly Ser 
    290                 295                 300


Ser Pro Lys Val Glu Phe Ser Asn Ala His Gly Phe Leu Leu Asp Thr 
305                 310                 315                 320


Ser Leu Glu Pro Pro Leu Cys Gly Gln Thr Leu Cys Asp Asn Thr Glu 
                325                 330                 335


Val Ile Ala Ser Tyr Asn Gln Leu Ser Ser Phe Arg Gln Pro Lys Val 
            340                 345                 350


Val Arg Tyr Arg Val Val Asn Leu Tyr Glu Asp Asp His Lys Asn Pro 
        355                 360                 365


Thr Val Thr Arg Glu Gln Val Asp Phe Gln His His Gln Leu Ala Glu 
    370                 375                 380


Ala Phe Lys Gln Tyr Asn Ile Ser Trp Glu Leu Asp Val Leu Glu Val 
385                 390                 395                 400


Ser Asn Ser Ser Leu Arg Arg Arg Leu Ile Leu Ala Asn Cys Asp Ile 
                405                 410                 415


Ser Lys Ile Gly Asp Glu Asn Cys Asp Pro Glu Cys Asn His Thr Leu 
            420                 425                 430


Thr Gly His Asp Gly Gly Asp Cys Arg His Leu Arg His Pro Ala Phe 
        435                 440                 445


Val Lys Lys Gln His Asn Gly Val Cys Asp Met Asp Cys Asn Tyr Glu 
    450                 455                 460


Arg Phe Asn Phe Asp Gly Gly Glu Cys Cys Asp Pro Glu Ile Thr Asn 
465                 470                 475                 480


Val Thr Gln Thr Cys Phe Asp Pro Asp Ser Pro His Arg Ala Tyr Leu 
                485                 490                 495


Asp Val Asn Glu Leu Lys Asn Ile Leu Lys Leu Asp Gly Ser Thr His 
            500                 505                 510


Leu Asn Ile Phe Phe Ala Lys Ser Ser Glu Glu Glu Leu Ala Gly Val 
        515                 520                 525


Ala Thr Trp Pro Trp Asp Lys Glu Ala Leu Met His Leu Gly Gly Ile 
    530                 535                 540


Val Leu Asn Pro Ser Phe Tyr Gly Met Pro Gly His Thr His Thr Met 
545                 550                 555                 560


Ile His Glu Ile Gly His Ser Leu Gly Leu Tyr His Val Phe Arg Gly 
                565                 570                 575


Ile Ser Glu Ile Gln Ser Cys Ser Asp Pro Cys Met Glu Thr Glu Pro 
            580                 585                 590


Ser Phe Glu Thr Gly Asp Leu Cys Asn Asp Thr Asn Pro Ala Pro Lys 
        595                 600                 605


His Lys Ser Cys Gly Asp Pro Gly Pro Gly Asn Asp Thr Cys Gly Phe 
    610                 615                 620


His Ser Phe Phe Asn Thr Pro Tyr Asn Asn Phe Met Ser Tyr Ala Asp 
625                 630                 635                 640


Asp Asp Cys Thr Asp Ser Phe Thr Pro Asn Gln Val Ala Arg Met His 
                645                 650                 655


Cys Tyr Leu Asp Leu Val Tyr Gln Gly Trp Gln Pro Ser Arg Lys Pro 
            660                 665                 670


Ala Pro Val Ala Leu Ala Pro Gln Val Leu Gly His Thr Thr Asp Ser 
        675                 680                 685


Val Thr Leu Glu Trp Phe Pro Pro Ile Asp Gly His Phe Phe Glu Arg 
    690                 695                 700


Glu Leu Gly Ser Ala Cys His Leu Cys Leu Glu Gly Arg Ile Leu Val 
705                 710                 715                 720


Gln Tyr Ala Ser Asn Ala Ser Ser Pro Met Pro Cys Ser Pro Ser Gly 
                725                 730                 735


His Trp Ser Pro Arg Glu Ala Glu Gly His Pro Asp Val Glu Gln Pro 
            740                 745                 750


Cys Lys Ser Ser Val Arg Thr Trp Ser Pro Asn Ser Ala Val Asn Pro 
        755                 760                 765


His Thr Val Pro Pro Ala Cys Pro Glu Pro Gln Gly Cys Tyr Leu Glu 
    770                 775                 780


Leu Glu Phe Leu Tyr Pro Leu Val Pro Glu Ser Leu Thr Ile Trp Val 
785                 790                 795                 800


Thr Phe Val Ser Thr Asp Trp Asp Ser Ser Gly Ala Val Asn Asp Ile 
                805                 810                 815


Lys Leu Leu Ala Val Ser Gly Lys Asn Ile Ser Leu Gly Pro Gln Asn 
            820                 825                 830


Val Phe Cys Asp Val Pro Leu Thr Ile Arg Leu Trp Asp Val Gly Glu 
        835                 840                 845


Glu Val Tyr Gly Ile Gln Ile Tyr Thr Leu Asp Glu His Leu Glu Ile 
    850                 855                 860


Asp Ala Ala Met Leu Thr Ser Thr Ala Asp Thr Pro Leu Cys Leu Gln 
865                 870                 875                 880


Cys Lys Pro Leu Lys Tyr Lys Val Val Arg Asp Pro Pro Leu Gln Met 
                885                 890                 895


Asp Val Ala Ser Ile Leu His Leu Asn Arg Lys Phe Val Asp Met Asp 
            900                 905                 910


Leu Asn Leu Gly Ser Val Tyr Gln Tyr Trp Val Ile Thr Ile Ser Gly 
        915                 920                 925


Thr Glu Glu Ser Glu Pro Ser Pro Ala Val Thr Tyr Ile His Gly Ser 
    930                 935                 940


Gly Tyr Cys Gly Asp Gly Ile Ile Gln Lys Asp Gln Gly Glu Gln Cys 
945                 950                 955                 960


Asp Asp Met Asn Lys Ile Asn Gly Asp Gly Cys Ser Leu Phe Cys Arg 
                965                 970                 975


Gln Glu Val Ser Phe Asn Cys Ile Asp Glu Pro Ser Arg Cys Tyr Phe 
            980                 985                 990


His Asp Gly Asp Gly Val Cys Glu Glu Phe Glu Gln Lys Thr Ser Ile 
        995                 1000                1005


Lys Asp Cys Gly Val Tyr Thr Pro Gln Gly Phe Leu Asp Gln Trp Ala 
    1010                1015                1020


Ser Asn Ala Ser Val Ser His Gln Asp Gln Gln Cys Pro Gly Trp Val 
1025                1030                1035                1040


Ile Ile Gly Gln Pro Ala Ala Ser Gln Val Cys Arg Thr Lys Val Ile 
                1045                1050                1055


Asp Leu Ser Glu Gly Ile Ser Gln His Ala Trp Tyr Pro Cys Thr Ile 
            1060                1065                1070


Ser Tyr Pro Tyr Ser Gln Leu Ala Gln Thr Thr Phe Trp Leu Arg Ala 
        1075                1080                1085


Tyr Phe Ser Gln Pro Met Val Ala Ala Ala Val Ile Val His Leu Val 
    1090                1095                1100


Thr Asp Gly Thr Tyr Tyr Gly Asp Gln Lys Gln Glu Thr Ile Ser Val 
1105                1110                1115                1120


Gln Leu Leu Asp Thr Lys Asp Gln Ser His Asp Leu Gly Leu His Val 
                1125                1130                1135


Leu Ser Cys Arg Asn Asn Pro Leu Ile Ile Pro Val Val His Asp Leu 
            1140                1145                1150


Ser Gln Pro Phe Tyr His Ser Gln Ala Val Arg Val Ser Phe Ser Ser 
        1155                1160                1165


Pro Leu Val Ala Ile Ser Gly Val Ala Leu Arg Ser Phe Asp Asn Phe 
    1170                1175                1180


Asp Pro Val Thr Leu Ser Ser Cys Gln Arg Gly Glu Thr Tyr Ser Pro 
1185                1190                1195                1200


Ala Glu Gln Ser Cys Val His Phe Ala Cys Glu Lys Thr Asp Cys Pro 
                1205                1210                1215


Glu Leu Ala Val Glu Asn Ala Ser Leu Asn Cys Ser Ser Ser Asp Arg 
            1220                1225                1230


Tyr His Gly Ala Gln Cys Thr Val Ser Cys Arg Thr Gly Tyr Val Leu 
        1235                1240                1245


Gln Ile Arg Arg Asp Asp Glu Leu Ile Lys Ser Gln Thr Gly Pro Ser 
    1250                1255                1260


Val Thr Val Thr Cys Thr Glu Gly Lys Trp Asn Lys Gln Val Ala Cys 
1265                1270                1275                1280


Glu Pro Val Asp Cys Ser Ile Pro Asp His His Gln Val Tyr Ala Ala 
                1285                1290                1295


Ser Phe Ser Cys Pro Glu Gly Thr Thr Phe Gly Ser Gln Cys Ser Phe 
            1300                1305                1310


Gln Cys Arg His Pro Ala Gln Leu Lys Gly Asn Asn Ser Leu Leu Thr 
        1315                1320                1325


Cys Met Glu Asp Gly Leu Trp Ser Phe Pro Glu Ala Leu Cys Glu Leu 
    1330                1335                1340


Met Cys Leu Ala Pro Pro Pro Val Pro Asn Ala Asp Leu Gln Thr Ala 
1345                1350                1355                1360


Arg Cys Arg Glu Asn Lys His Lys Val Gly Ser Phe Cys Lys Tyr Lys 
                1365                1370                1375


Cys Lys Pro Gly Tyr His Val Pro Gly Ser Ser Arg Lys Ser Lys Lys 
            1380                1385                1390


Arg Ala Phe Lys Thr Gln Cys Thr Gln Asp Gly Ser Trp Gln Glu Gly 
        1395                1400                1405


Ala Cys Val Pro Val Thr Cys Asp Pro Pro Pro Pro Lys Phe His Gly 
    1410                1415                1420


Leu Tyr Gln Cys Thr Asn Gly Phe Gln Phe Asn Ser Glu Cys Arg Ile 
1425                1430                1435                1440


Lys Cys Glu Asp Ser Asp Ala Ser Gln Gly Leu Gly Ser Asn Val Ile 
                1445                1450                1455


His Cys Arg Lys Asp Gly Thr Trp Asn Gly Ser Phe His Val Cys Gln 
            1460                1465                1470


Glu Met Gln Gly Gln Cys Ser Val Pro Asn Glu Leu Asn Ser Asn Leu 
        1475                1480                1485


Lys Leu Gln Cys Pro Asp Gly Tyr Ala Ile Gly Ser Glu Cys Ala Thr 
    1490                1495                1500


Ser Cys Leu Asp His Asn Ser Glu Ser Ile Ile Leu Pro Met Asn Val 
1505                1510                1515                1520


Thr Val Arg Asp Ile Pro His Trp Leu Asn Pro Thr Arg Val Glu Arg 
                1525                1530                1535


Val Val Cys Thr Ala Gly Leu Lys Trp Tyr Pro His Pro Ala Leu Ile 
            1540                1545                1550


His Cys Val Lys Gly Cys Glu Pro Phe Met Gly Asp Asn Tyr Cys Asp 
        1555                1560                1565


Ala Ile Asn Asn Arg Ala Phe Cys Asn Tyr Asp Gly Gly Asp Cys Cys 
    1570                1575                1580


Thr Ser Thr Val Lys Thr Lys Lys Val Thr Pro Phe Pro Met Ser Cys 
1585                1590                1595                1600


Asp Leu Gln Gly Asp Cys Ala Cys Arg Asp Pro Gln Ala Gln Glu His 
                1605                1610                1615


Ser Arg Lys Asp Leu Arg Gly Tyr Ser His Gly 
            1620                1625


<210>  6334
<211>  10991
<212>  DNA
<213>  Homo sapiens

<400>  6334
cgcaaaaaat aaataaatta gagcatcttt tggggggagg gaattcagcg gatcagtctt     60

aagaggagct tttttttgga gcgagaaatc atataaaata aaatgaaata aaacaaggag    120

gaaggcaacc agctgttagg ggaaaaataa ggcagataaa ggagcgggga gagaaattaa    180

ttgccaacca ggaggagttg ggctgtattt ttcaaaggtg gggagagtgg agcacacacc    240

ttgaggagga aagcgagaaa gaaaagaaaa aagcaagtgg aaaggggggc tcgcccaaga    300

agggtgaaga agcgaagaaa gtcgaggcgc cgaggctccc aaagctggca gctccgggtg    360

gcggtgcagg ggcgaagggg gggcgggggg aaccgtcgga catgcggctc tggagttggg    420

tgctgcacct ggggctgctg agcgccgcgc tgggctgcgg gctggccgag cgtccccgcc    480

gggcccggag agacccgcgg gccggccgac ccccgcgccc cgccgccggc ccggccacct    540

gcgccacccg ggcggcccgc ggccgccgcg cctcgccgcc gccgccgccg ccgccgggcg    600

gtgcctggga agccgtgcgc gtcccccggc ggcggcagca gcgggaggcg aggggcgcca    660

ccgaggagcc gagcccgccg agccgggcgc tctatttcag cgggcgaggc gagcagctgc    720

gcctccgggc cgacctcgag ctgccccggg acgcgttcac gctgcaagtg tggctgcgag    780

cggagggggg ccagaggtct ccggcagtga tcacagggct gtatgacaaa tgttcttata    840

tctcacgtga ccgaggatgg gtcgtgggca ttcacaccat cagtgaccaa gacaacaaag    900

acccacgcta ctttttctcc ttgaagacag accgagcccg gcaagtgacc accatcaatg    960

cccaccgcag ctacctccca ggccagtggg tatacctagc tgccacctat gatgggcagt   1020

tcatgaagct ctatgtgaat ggtgcccagg tggccacctc tggggaacaa gtgggtggca   1080

tattcagccc actgacccag aagtgcaaag tgctcatgtt agggggcagt gccctgaatc   1140

acaactaccg gggctacatc gagcacttca gtctgtggaa ggtggccagg actcagcggg   1200

agatactgtc tgacatggaa acccatggcg cccacactgc tctacctcag ctcctcctcc   1260

aggagaactg ggacaatgtg aagcatgcct ggtcccccat gaaggatggc agcagcccca   1320

aagtggaatt cagcaatgcc cacggctttc tgctggacac gagtctggag cctcctctgt   1380

gcggacagac attgtgtgac aacacagagg tcattgccag ctacaatcag ctctcaagtt   1440

tccgccagcc caaggtggtg cgctaccgcg tggtcaacct ctatgaagat gatcataaga   1500

acccgacggt gacgcgcgag caggtggact tccagcacca tcagctggct gaggccttca   1560

agcaatacaa catctcctgg gagctggacg tgctggaggt gagcaactcc tcccttcgcc   1620

gccgcctcat cctggccaac tgtgacatca gcaagattgg ggatgagaac tgtgaccccg   1680

agtgcaacca cacgctgacg ggccacgacg gcggggattg ccgccacctg cgccaccctg   1740

ccttcgtgaa gaagcagcac aacggggtgt gtgacatgga ctgcaactat gaacggttca   1800

actttgatgg tggagagtgc tgtgaccctg aaatcaccaa tgtcactcag acttgctttg   1860

accccgactc tccacacaga gcctacttgg atgttaatga gctgaagaac attcttaaat   1920

tggatggatc aacacatctc aatattttct ttgcaaaatc ctcagaggag gagttggcag   1980

gagtagcaac ttggccatgg gacaaggagg ccctgatgca cttaggtggc attgtcttga   2040

acccatcttt ctatggcatg cctgggcaca cccacaccat gatccatgag attggtcaca   2100

gcctgggcct ctatcacgtc ttccgaggca tctcagaaat ccagtcctgc agtgacccct   2160

gcatggagac agagccctcc ttcgagactg gagacctctg caatgatacc aacccagccc   2220

ctaaacacaa gtcctgtggt gacccagggc caggaaatga cacctgtggc tttcatagct   2280

tcttcaacac tccttacaac aacttcatga gctatgcaga tgacgactgt acggactcct   2340

tcacgcccaa tcaagtcgcc agaatgcact gttacctgga cctggtctac cagggctggc   2400

agccctccag gaaaccagcg cctgttgccc tcgcccccca agttctgggc cacacaacgg   2460

actctgtgac actggagtgg ttcccaccta tagatggcca tttctttgaa agagaattgg   2520

gatcagcatg tcatctttgc ctggaaggga gaatcctggt gcagtatgct tccaacgctt   2580

cctccccaat gccctgcagc ccatcaggac actggagccc tcgtgaagca gaaggtcatc   2640

ctgatgttga acagccctgt aagtccagtg tccgcacctg gagcccaaat tcagctgtca   2700

acccacacac ggttcctcca gcctgccctg agcctcaagg ctgctacctc gagctggagt   2760

tcctctaccc cttggtccct gagtctctga ccatttgggt gacctttgtc tccactgact   2820

gggactctag tggagctgtc aatgacatca aactgttggc tgtcagtggg aagaacatct   2880

ccctgggtcc tcagaatgtc ttctgtgatg tcccactgac catcagactc tgggacgtgg   2940

gcgaggaggt gtatggcatc caaatctaca cgctggatga gcacctggag atcgatgctg   3000

ccatgttgac ctccactgca gacaccccac tctgtctaca gtgtaagccc ctgaagtata   3060

aggtggtccg ggaccctcct ctccagatgg atgtggcctc catcctacat ctcaatagga   3120

aattcgtaga catggatcta aatcttggca gtgtgtacca gtattgggtc ataactattt   3180

caggaactga agagagtgag ccatcacctg ctgtcacata catccatgga agtgggtact   3240

gtggcgatgg cattatacaa aaagaccaag gtgaacaatg cgacgacatg aataagatca   3300

atggtgatgg ctgctccctt ttctgccgac aagaagtctc cttcaattgt attgatgaac   3360

ccagccggtg ctatttccat gatggtgatg gggtatgtga ggagtttgaa caaaaaacca   3420

gcattaagga ctgtggtgtc tacacgcccc agggattcct ggatcagtgg gcatccaatg   3480

cttcagtatc tcatcaagac cagcaatgcc caggctgggt catcatcgga cagccagcag   3540

catcccaggt gtgtcgaacc aaggtgatag atctcagtga aggcatttcc cagcatgcct   3600

ggtacccttg caccatcagc tacccatatt cccagctggc tcagaccact ttttggctcc   3660

gggcgtattt ttctcaacca atggttgccg cagctgtcat tgtccacctg gtgacggatg   3720

ggacatatta tggggaccaa aagcaggaga ccatcagcgt gcagctgctt gataccaaag   3780

atcagagcca cgatctaggc ctccatgtcc tgagctgcag gaacaatccc ctgattatcc   3840

ctgtggtcca tgacctcagc cagcccttct accacagcca ggcggtacgt gtgagcttca   3900

gttcgcccct ggtcgccatc tcgggggtgg ccctccgttc cttcgacaac tttgaccccg   3960

tcaccctgag cagctgccag agaggggaga cctacagccc tgccgagcag agctgcgtgc   4020

acttcgcatg tgagaaaact gactgtccag agctggctgt ggagaatgct tctctcaatt   4080

gctccagcag cgaccgctac cacggtgccc agtgtactgt gagctgccgg acaggctacg   4140

tgctccagat acggcgggat gatgagctga tcaagagcca gacgggaccc agcgtcacag   4200

tgacctgtac agagggcaag tggaataagc aggtggcctg tgagccagtc gactgcagca   4260

tcccagatca ccatcaagtc tatgctgcct ccttctcctg ccctgagggc accacctttg   4320

gcagtcaatg ttccttccag tgccgtcacc ctgcacaatt gaaaggcaac aacagcctcc   4380

tgacctgcat ggaggatggg ctgtggtcct tcccagaggc cctgtgtgag ctcatgtgcc   4440

tcgctccacc ccctgtgccc aatgcagacc tccagaccgc ccggtgccga gagaataagc   4500

acaaggtggg ctccttctgc aaatacaaat gcaagcctgg ataccatgtg cctggatcct   4560

ctcggaagtc aaagaaacgg gccttcaaga ctcagtgtac ccaggatggc agctggcagg   4620

agggagcttg tgttcctgtg acctgtgacc cacctccacc aaaattccat gggctctacc   4680

agtgtactaa tggcttccag ttcaacagtg agtgtaggat caagtgtgaa gacagtgatg   4740

cctcccaggg acttgggagc aatgtcattc attgccggaa agatggcacc tggaacggct   4800

ccttccatgt ctgccaggag atgcaaggcc agtgctcggt tccaaacgag ctcaacagca   4860

acctcaaact gcagtgccct gatggctatg ccatagggtc ggagtgtgcc acctcgtgcc   4920

tggaccacaa cagcgagtcc atcatcctgc caatgaacgt gaccgtgcgt gacatccccc   4980

actggctgaa ccccacacgg gtagagagag ttgtctgcac tgctggtctc aagtggtatc   5040

ctcaccctgc tctgattcac tgtgtcaaag gctgtgagcc cttcatggga gacaattatt   5100

gtgatgccat caacaaccga gccttttgca actatgacgg tggggattgc tgcacctcca   5160

cagtgaagac caaaaaggtc accccattcc ctatgtcctg tgatctacaa ggtgactgtg   5220

cttgtcggga cccccaggcc caagaacaca gccggaaaga cctccgggga tacagccatg   5280

gctaaggaag gacaagaagt tgtcaaagaa ttcccaacgc caggacccac atccctttgg   5340

tattgatttc acagtcagct gctcaacgga atggcctctc cacaccaggg atccttagca   5400

cccaaccggt ctgcctttaa ttttacccag gaaggactca cattggggcg aatgaaccaa   5460

gtttcgccat gctggatgat gaaatggatt cccatcccaa agtctgagat ggattgcata   5520

tacagtgtgc agtcccagag cctcctaaaa ttctagccat ttgtcacaca accacagcaa   5580

gaaacgtgtt ctatatctag agtgtgccca tctgtgttta gtacacatgc atgcatacac   5640

acccatacaa acatctgtgt gagggcagtt ctggagatga gcagagagag accggaataa   5700

actcaatctt ttctttccca agctcctagc caacactatc cttgggagaa agaaatttgc   5760

agaaactgct aagaccaagt gtggagatgt caagctagtt cacactctga ggctcagaat   5820

atgtaggaca tgcacaattg tgcagtcctt tgggattgga agtgaaacag tctgtgatcc   5880

cctaccttct agggaactag gacctaggaa gaggtaaaga ttatcaggta tgcaaagcgc   5940

cccaattctt ctgctgccat gggggatttt accccaactc cagggttcga ggccaatctg   6000

agaatggctt aggattgcaa tgtcaaggta ttatatcagc cccttgcttg aggcttgagg   6060

tcataatatc cctctaggac ttacctgttc ccccagatct tgccttggga ccacatttgc   6120

tgctactttt cctgctgctc tatcctatac attgaataat ccaagatggt agaactaggt   6180

taggaaaaat tccacacaac caaacagtct gccttaaaag tgacccacat ttttccatag   6240

ctcctcactt tttagccctt ctgcaagaga aaaaccctca tgggtccaca tggtgagaag   6300

ttaagtttcc tgtaagtggg cctctcaccc tggaaaggag ttgagggaca tcagatgctg   6360

gaaccctcac tgaaagtcca gaatgtctaa gccagtgtta gattttgtaa acaagtggaa   6420

cagtgttaaa tttctatgat gttggagcca tccagagact actggaattg tcgagacttt   6480

tggattatta tccttatcct tatcctaatc ttcctagccc ttcaggctag agtaggcttt   6540

gatcctgaga accttgctgt tgctctgagg agatataatt ctgggagaaa gaatctttta   6600

taagaacagt acagattgtt ctcaagaggg ccatcagaag gaagccaaag agttcacagc   6660

ctcagcacca acaactcaac atggtcatca tgttttctat atggtttttc cagctagcag   6720

tactcccttc catacctgtg actgggcagt gcttttctct ctcccatgtc tagcctccaa   6780

aagttaagtg aaaattagtc aactgcacgt ggaagccccc accactttgg ggatctcttt   6840

atttcttttc agccagggac ctgtccactc cctttgaatt aatatgggaa gaaattaata   6900

caggatgaac tggagagaag ggttgagtgt ggcatacttt ctgaaacctg gagctgggaa   6960

ttgcggagaa gggaaggtct agactagtta catcacatag ggattactgt aaatcaagtc   7020

atctcaagtc tagtgaagac agccaacaga aacaaaacct agcataggga tagaaaatac   7080

catgcacgtg tgcagcccca cctaattcct gcatccaagg caggtgttgt taatctatca   7140

tagcacttaa aaaaaaaaaa aaaaagagac caaaaataac tttaggaacc accatattat   7200

atcactccca atagcactga cctggtgatc aaaaacactt gagaagacat ctattggcca   7260

tctctggcca attacactaa gaaacatatc aaggtgcttt tggcacaggt gcccacaaat   7320

acggatgcag tgctgagata gtttatgaga cttgtaccat ttcacaaact ctgaaattgg   7380

gttccatatt ggcaaggctg ccacagttgt taagaataat cctctatgtt tcttcctcac   7440

aaaaccatat ctcatttata tccagaccat tacttcacta taattacaag gacaaattat   7500

tagcaagaaa taagaatagt attagaagaa ttgatcctat tttgaacccc tctccagtat   7560

cttcacactc ttgtcaactc tccaggcctc tctcttgccc tgagttatca gcctgtgtgg   7620

tgttaactac cttagaaggt acaagctaag aaatgtaaca gtatcaaccc tcccagttgc   7680

ttaattatac ccataggtaa tacaaaaagc tctgaagacc caaagatgac attactaatg   7740

atgtgatttc aggagccaca gaagaacctt accagcttcc ctcaaatcag tccttatcct   7800

ctttctatct tcactcccat catcatctat tttcacacta tccagctaag caaagattcc   7860

tggaggctga cttgtatctt cagactcaca gagtgaattc agctcttctg aatcaagacc   7920

cacccagtct ctttcattca gacctgttgc taacaaattt atatttgcca aggatattag   7980

gcaaaagagg ctacttgatt ggtggccaac ctcgtgccca catggaaggt atctttaata   8040

gggtcttttc aaaccttagt ggaggagggt cagctcaatt tgggcaatgc atttgttccc   8100

agtttcattt tcttcctggg aattaactcg tcatttcatt ccttcagtca tcttctgtgt   8160

aggtgaccgg agcactgaga ggcagctctg atgcactatt gtgtgtcagc agctcaaagg   8220

ccctaaaaca ctgaaggttc tgcatctgaa gtattagatt gttagcagca aaatatgaaa   8280

gatgaggtgg acagtcctct aagccctatt tagggaagct tttccaagcc acaatcttaa   8340

ctacctaccc aaaggatttg cattaccccc agattctgtg ccaacaacct tttaaggaaa   8400

tacagtcctt gggaaatgag ttttgatggt gaattggggt gttaaggaag ggaaagattg   8460

tcatagatgg tagggctttg aaaatgcagg gtatcagctg ccactcctgg cttcaacaca   8520

ttgagtcact gcctagacgg ttctcttggt cttattccca tcctggccaa tgcttaaata   8580

ctatttgttg aaaataattc tttgagacag atttcagcta cctcccttcc aggttcgatt   8640

taacttggtt gtaattgtca atttgttgtt ataggtctta cctgtgtgaa agaaagaaaa   8700

agaaagaaag aaagaaagag aaaggaaatt ataaggtcaa gttaacagtt ttgaggtttt   8760

gtgttttttt ctggaactac ttcaagtgag aaaataaaaa aaaatggtga caaagctgta   8820

cagatagaga taatagaaga caaagagatt aaaaggaaat aaaaatgcat gattaaaaac   8880

taagaataaa aaacctattt ttatgtttcc taaaggaaat tgtttattct acagcctcag   8940

taggtagaca caaacataaa gatttcccta gaagacatag agtgggattt gataacactg   9000

tctgttattt tctgtacatt gtggtaggtc caggaaatat gacattttcc cccttgatgt   9060

gttattgttg ttgttgggtg gggtgggcat tttgtttatt tgtttggtgg caatcagtgg   9120

tagtagggag tgggagggct tatattggtt tttccagcta ttaaggggac atattgtgtc   9180

gttgtgcttt tcacgttata aaatgtttat atttaccagt acagcactgg gctttataaa   9240

gactgcactc agaaccacac tgcacagtcc agttttttaa aaagctgcta catgacagac   9300

aggtaatccc actgagtgag ttttgagaaa caaatcaaac gaagtaaaca agaaacataa   9360

aaaccaaata gcaaatgaat aaaagcctgt tcttgtaact tattcaactt ttgccaaatt   9420

cctaccaatc acttgctttt taaaagaaat gtataatagc caaaagagaa attatgtccc   9480

tgttgtacag aagttagaat ttttgactcc aggcagcagt ttgctcagtg atcttgaaca   9540

agttatccaa ttgcctctac atttgcatca gtttctctag ctgcaaaatg gggataatac   9600

tatataccta cctcacagtg ggagggcagg agattttgag gccctgaggt tttaggtggg   9660

ctgtgagggc caacgcttga cacaaagtcc atgggttatt attcaagaat gcacaggccc   9720

atcggccttt tagaaagaca agacagggag tgcttgtttg atatttcaag gaataaagcc   9780

ggagctcctg aattgtagtc caccttaaaa gagagacctg tattggagaa tattttattt   9840

ttttggcaaa tttgatctta ccctttacca gttctataat ttggttaaaa gctgattatg   9900

tcctacaatg tcaaagtcag ctaactgtcg tctacttaag acttctggtc atttccaact   9960

tatagaggaa gggagtctct aaaatctctt cttcagaagg cacctcactt ctcagactta  10020

aaattccaca tcaagtgttc cattaaaaga agataaggca ttctgagtgc aaacaaatgg  10080

gggcttctta aactacacac cagcagtcag tgaggaaaac tttgaacaat tattgagttg  10140

ctttcttggg tctctataat caataacctg tctgcagata tctatctata taaagatatt  10200

atatataaat ataaatttac atatatatgc acatgtatat atagttgtac atatatgtgt  10260

gtatatatat acttaaatgt aatatttaca aaataaaact gtgatctcgt ctagagaaaa  10320

tgtattcata ttacaaactg ctcttccata tttatgtacc atattatacc tttttattat  10380

tgttataatt attatgggta tttctaatta atatgatgtt gaaacctgtt tggcaccttc  10440

tggaagctac caaaaaaatg acactccatt gaagtgctta aaagctgttc tcataagaat  10500

tcttctggcc tattgtaaaa aagaaaaaaa aaaagaaaaa gaagaaagac acaaagaaaa  10560

taatctaaac accaaaaact aaacacaatt ccaatccttt ttctgtacct cacgcgcata  10620

aatttgctgc tcctattttt ttttctgttt atgtgttttt atggatctaa gttaaatctt  10680

ttggcaatat ataaaaatgt aaatagtaaa ctttatttat taagaatgtc atctttttta  10740

atttatattt acacaattgt tcatctaatt tattttttct atacagtttt aaatactcag  10800

acatattttg ctgttcatga tatttttatc ctgttctcat ggatttgttt tcccatactg  10860

ttttctctga tctcaattac aggttggatc tcacaaataa taatgtcaga gacagaaata  10920

ttttgccact gttgattact atactttaaa gttctatatt atgaaaatat ataatagctt  10980

gtacgcttca g                                                       10991


<210>  6335
<211>  1627
<212>  PRT
<213>  Homo sapiens

<400>  6335

Met Arg Leu Trp Ser Trp Val Leu His Leu Gly Leu Leu Ser Ala Ala 
1               5                   10                  15


Leu Gly Cys Gly Leu Ala Glu Arg Pro Arg Arg Ala Arg Arg Asp Pro 
            20                  25                  30


Arg Ala Gly Arg Pro Pro Arg Pro Ala Ala Gly Pro Ala Thr Cys Ala 
        35                  40                  45


Thr Arg Ala Ala Arg Gly Arg Arg Ala Ser Pro Pro Pro Pro Pro Pro 
    50                  55                  60


Pro Gly Gly Ala Trp Glu Ala Val Arg Val Pro Arg Arg Arg Gln Gln 
65                  70                  75                  80


Arg Glu Ala Arg Gly Ala Thr Glu Glu Pro Ser Pro Pro Ser Arg Ala 
                85                  90                  95


Leu Tyr Phe Ser Gly Arg Gly Glu Gln Leu Arg Leu Arg Ala Asp Leu 
            100                 105                 110


Glu Leu Pro Arg Asp Ala Phe Thr Leu Gln Val Trp Leu Arg Ala Glu 
        115                 120                 125


Gly Gly Gln Arg Ser Pro Ala Val Ile Thr Gly Leu Tyr Asp Lys Cys 
    130                 135                 140


Ser Tyr Ile Ser Arg Asp Arg Gly Trp Val Val Gly Ile His Thr Ile 
145                 150                 155                 160


Ser Asp Gln Asp Asn Lys Asp Pro Arg Tyr Phe Phe Ser Leu Lys Thr 
                165                 170                 175


Asp Arg Ala Arg Gln Val Thr Thr Ile Asn Ala His Arg Ser Tyr Leu 
            180                 185                 190


Pro Gly Gln Trp Val Tyr Leu Ala Ala Thr Tyr Asp Gly Gln Phe Met 
        195                 200                 205


Lys Leu Tyr Val Asn Gly Ala Gln Val Ala Thr Ser Gly Glu Gln Val 
    210                 215                 220


Gly Gly Ile Phe Ser Pro Leu Thr Gln Lys Cys Lys Val Leu Met Leu 
225                 230                 235                 240


Gly Gly Ser Ala Leu Asn His Asn Tyr Arg Gly Tyr Ile Glu His Phe 
                245                 250                 255


Ser Leu Trp Lys Val Ala Arg Thr Gln Arg Glu Ile Leu Ser Asp Met 
            260                 265                 270


Glu Thr His Gly Ala His Thr Ala Leu Pro Gln Leu Leu Leu Gln Glu 
        275                 280                 285


Asn Trp Asp Asn Val Lys His Ala Trp Ser Pro Met Lys Asp Gly Ser 
    290                 295                 300


Ser Pro Lys Val Glu Phe Ser Asn Ala His Gly Phe Leu Leu Asp Thr 
305                 310                 315                 320


Ser Leu Glu Pro Pro Leu Cys Gly Gln Thr Leu Cys Asp Asn Thr Glu 
                325                 330                 335


Val Ile Ala Ser Tyr Asn Gln Leu Ser Ser Phe Arg Gln Pro Lys Val 
            340                 345                 350


Val Arg Tyr Arg Val Val Asn Leu Tyr Glu Asp Asp His Lys Asn Pro 
        355                 360                 365


Thr Val Thr Arg Glu Gln Val Asp Phe Gln His His Gln Leu Ala Glu 
    370                 375                 380


Ala Phe Lys Gln Tyr Asn Ile Ser Trp Glu Leu Asp Val Leu Glu Val 
385                 390                 395                 400


Ser Asn Ser Ser Leu Arg Arg Arg Leu Ile Leu Ala Asn Cys Asp Ile 
                405                 410                 415


Ser Lys Ile Gly Asp Glu Asn Cys Asp Pro Glu Cys Asn His Thr Leu 
            420                 425                 430


Thr Gly His Asp Gly Gly Asp Cys Arg His Leu Arg His Pro Ala Phe 
        435                 440                 445


Val Lys Lys Gln His Asn Gly Val Cys Asp Met Asp Cys Asn Tyr Glu 
    450                 455                 460


Arg Phe Asn Phe Asp Gly Gly Glu Cys Cys Asp Pro Glu Ile Thr Asn 
465                 470                 475                 480


Val Thr Gln Thr Cys Phe Asp Pro Asp Ser Pro His Arg Ala Tyr Leu 
                485                 490                 495


Asp Val Asn Glu Leu Lys Asn Ile Leu Lys Leu Asp Gly Ser Thr His 
            500                 505                 510


Leu Asn Ile Phe Phe Ala Lys Ser Ser Glu Glu Glu Leu Ala Gly Val 
        515                 520                 525


Ala Thr Trp Pro Trp Asp Lys Glu Ala Leu Met His Leu Gly Gly Ile 
    530                 535                 540


Val Leu Asn Pro Ser Phe Tyr Gly Met Pro Gly His Thr His Thr Met 
545                 550                 555                 560


Ile His Glu Ile Gly His Ser Leu Gly Leu Tyr His Val Phe Arg Gly 
                565                 570                 575


Ile Ser Glu Ile Gln Ser Cys Ser Asp Pro Cys Met Glu Thr Glu Pro 
            580                 585                 590


Ser Phe Glu Thr Gly Asp Leu Cys Asn Asp Thr Asn Pro Ala Pro Lys 
        595                 600                 605


His Lys Ser Cys Gly Asp Pro Gly Pro Gly Asn Asp Thr Cys Gly Phe 
    610                 615                 620


His Ser Phe Phe Asn Thr Pro Tyr Asn Asn Phe Met Ser Tyr Ala Asp 
625                 630                 635                 640


Asp Asp Cys Thr Asp Ser Phe Thr Pro Asn Gln Val Ala Arg Met His 
                645                 650                 655


Cys Tyr Leu Asp Leu Val Tyr Gln Gly Trp Gln Pro Ser Arg Lys Pro 
            660                 665                 670


Ala Pro Val Ala Leu Ala Pro Gln Val Leu Gly His Thr Thr Asp Ser 
        675                 680                 685


Val Thr Leu Glu Trp Phe Pro Pro Ile Asp Gly His Phe Phe Glu Arg 
    690                 695                 700


Glu Leu Gly Ser Ala Cys His Leu Cys Leu Glu Gly Arg Ile Leu Val 
705                 710                 715                 720


Gln Tyr Ala Ser Asn Ala Ser Ser Pro Met Pro Cys Ser Pro Ser Gly 
                725                 730                 735


His Trp Ser Pro Arg Glu Ala Glu Gly His Pro Asp Val Glu Gln Pro 
            740                 745                 750


Cys Lys Ser Ser Val Arg Thr Trp Ser Pro Asn Ser Ala Val Asn Pro 
        755                 760                 765


His Thr Val Pro Pro Ala Cys Pro Glu Pro Gln Gly Cys Tyr Leu Glu 
    770                 775                 780


Leu Glu Phe Leu Tyr Pro Leu Val Pro Glu Ser Leu Thr Ile Trp Val 
785                 790                 795                 800


Thr Phe Val Ser Thr Asp Trp Asp Ser Ser Gly Ala Val Asn Asp Ile 
                805                 810                 815


Lys Leu Leu Ala Val Ser Gly Lys Asn Ile Ser Leu Gly Pro Gln Asn 
            820                 825                 830


Val Phe Cys Asp Val Pro Leu Thr Ile Arg Leu Trp Asp Val Gly Glu 
        835                 840                 845


Glu Val Tyr Gly Ile Gln Ile Tyr Thr Leu Asp Glu His Leu Glu Ile 
    850                 855                 860


Asp Ala Ala Met Leu Thr Ser Thr Ala Asp Thr Pro Leu Cys Leu Gln 
865                 870                 875                 880


Cys Lys Pro Leu Lys Tyr Lys Val Val Arg Asp Pro Pro Leu Gln Met 
                885                 890                 895


Asp Val Ala Ser Ile Leu His Leu Asn Arg Lys Phe Val Asp Met Asp 
            900                 905                 910


Leu Asn Leu Gly Ser Val Tyr Gln Tyr Trp Val Ile Thr Ile Ser Gly 
        915                 920                 925


Thr Glu Glu Ser Glu Pro Ser Pro Ala Val Thr Tyr Ile His Gly Ser 
    930                 935                 940


Gly Tyr Cys Gly Asp Gly Ile Ile Gln Lys Asp Gln Gly Glu Gln Cys 
945                 950                 955                 960


Asp Asp Met Asn Lys Ile Asn Gly Asp Gly Cys Ser Leu Phe Cys Arg 
                965                 970                 975


Gln Glu Val Ser Phe Asn Cys Ile Asp Glu Pro Ser Arg Cys Tyr Phe 
            980                 985                 990


His Asp Gly Asp Gly Val Cys Glu Glu Phe Glu Gln Lys Thr Ser Ile 
        995                 1000                1005


Lys Asp Cys Gly Val Tyr Thr Pro Gln Gly Phe Leu Asp Gln Trp Ala 
    1010                1015                1020


Ser Asn Ala Ser Val Ser His Gln Asp Gln Gln Cys Pro Gly Trp Val 
1025                1030                1035                1040


Ile Ile Gly Gln Pro Ala Ala Ser Gln Val Cys Arg Thr Lys Val Ile 
                1045                1050                1055


Asp Leu Ser Glu Gly Ile Ser Gln His Ala Trp Tyr Pro Cys Thr Ile 
            1060                1065                1070


Ser Tyr Pro Tyr Ser Gln Leu Ala Gln Thr Thr Phe Trp Leu Arg Ala 
        1075                1080                1085


Tyr Phe Ser Gln Pro Met Val Ala Ala Ala Val Ile Val His Leu Val 
    1090                1095                1100


Thr Asp Gly Thr Tyr Tyr Gly Asp Gln Lys Gln Glu Thr Ile Ser Val 
1105                1110                1115                1120


Gln Leu Leu Asp Thr Lys Asp Gln Ser His Asp Leu Gly Leu His Val 
                1125                1130                1135


Leu Ser Cys Arg Asn Asn Pro Leu Ile Ile Pro Val Val His Asp Leu 
            1140                1145                1150


Ser Gln Pro Phe Tyr His Ser Gln Ala Val Arg Val Ser Phe Ser Ser 
        1155                1160                1165


Pro Leu Val Ala Ile Ser Gly Val Ala Leu Arg Ser Phe Asp Asn Phe 
    1170                1175                1180


Asp Pro Val Thr Leu Ser Ser Cys Gln Arg Gly Glu Thr Tyr Ser Pro 
1185                1190                1195                1200


Ala Glu Gln Ser Cys Val His Phe Ala Cys Glu Lys Thr Asp Cys Pro 
                1205                1210                1215


Glu Leu Ala Val Glu Asn Ala Ser Leu Asn Cys Ser Ser Ser Asp Arg 
            1220                1225                1230


Tyr His Gly Ala Gln Cys Thr Val Ser Cys Arg Thr Gly Tyr Val Leu 
        1235                1240                1245


Gln Ile Arg Arg Asp Asp Glu Leu Ile Lys Ser Gln Thr Gly Pro Ser 
    1250                1255                1260


Val Thr Val Thr Cys Thr Glu Gly Lys Trp Asn Lys Gln Val Ala Cys 
1265                1270                1275                1280


Glu Pro Val Asp Cys Ser Ile Pro Asp His His Gln Val Tyr Ala Ala 
                1285                1290                1295


Ser Phe Ser Cys Pro Glu Gly Thr Thr Phe Gly Ser Gln Cys Ser Phe 
            1300                1305                1310


Gln Cys Arg His Pro Ala Gln Leu Lys Gly Asn Asn Ser Leu Leu Thr 
        1315                1320                1325


Cys Met Glu Asp Gly Leu Trp Ser Phe Pro Glu Ala Leu Cys Glu Leu 
    1330                1335                1340


Met Cys Leu Ala Pro Pro Pro Val Pro Asn Ala Asp Leu Gln Thr Ala 
1345                1350                1355                1360


Arg Cys Arg Glu Asn Lys His Lys Val Gly Ser Phe Cys Lys Tyr Lys 
                1365                1370                1375


Cys Lys Pro Gly Tyr His Val Pro Gly Ser Ser Arg Lys Ser Lys Lys 
            1380                1385                1390


Arg Ala Phe Lys Thr Gln Cys Thr Gln Asp Gly Ser Trp Gln Glu Gly 
        1395                1400                1405


Ala Cys Val Pro Val Thr Cys Asp Pro Pro Pro Pro Lys Phe His Gly 
    1410                1415                1420


Leu Tyr Gln Cys Thr Asn Gly Phe Gln Phe Asn Ser Glu Cys Arg Ile 
1425                1430                1435                1440


Lys Cys Glu Asp Ser Asp Ala Ser Gln Gly Leu Gly Ser Asn Val Ile 
                1445                1450                1455


His Cys Arg Lys Asp Gly Thr Trp Asn Gly Ser Phe His Val Cys Gln 
            1460                1465                1470


Glu Met Gln Gly Gln Cys Ser Val Pro Asn Glu Leu Asn Ser Asn Leu 
        1475                1480                1485


Lys Leu Gln Cys Pro Asp Gly Tyr Ala Ile Gly Ser Glu Cys Ala Thr 
    1490                1495                1500


Ser Cys Leu Asp His Asn Ser Glu Ser Ile Ile Leu Pro Met Asn Val 
1505                1510                1515                1520


Thr Val Arg Asp Ile Pro His Trp Leu Asn Pro Thr Arg Val Glu Arg 
                1525                1530                1535


Val Val Cys Thr Ala Gly Leu Lys Trp Tyr Pro His Pro Ala Leu Ile 
            1540                1545                1550


His Cys Val Lys Gly Cys Glu Pro Phe Met Gly Asp Asn Tyr Cys Asp 
        1555                1560                1565


Ala Ile Asn Asn Arg Ala Phe Cys Asn Tyr Asp Gly Gly Asp Cys Cys 
    1570                1575                1580


Thr Ser Thr Val Lys Thr Lys Lys Val Thr Pro Phe Pro Met Ser Cys 
1585                1590                1595                1600


Asp Leu Gln Gly Asp Cys Ala Cys Arg Asp Pro Gln Ala Gln Glu His 
                1605                1610                1615


Ser Arg Lys Asp Leu Arg Gly Tyr Ser His Gly 
            1620                1625


<210>  6336
<211>  448
<212>  DNA
<213>  Homo sapiens

<400>  6336
aactacaccc tatagacacc ttagacacca gcttaaaacc tggaaaggtt acatttagta     60

tgtttatgtt cttacccatc atccacattc cattaagaca ccttagtatc cagagaactg    120

tgataaatgc tgtaggggtc caagatataa tctctgtctt caaggtgctt gtatcctgtg    180

attcaatgac attttgttac agtcattcaa gagaagttag gaaaggttta atgatggaga    240

agggatgcaa taggctttta gcataagcag gctttgtaat aatagaaaag agctggtggg    300

ctggccagac atgtagtgat aatagggtaa ataaattgaa gtgggaagat gttgaggaga    360

tgcaagaaag atgtgagtct ggttggggct tcatgaaggt agatgccaca gttttttctt    420

cagactgtag acactgaaga ctcgggct                                       448


<210>  6337
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  6337

Met Phe Met Phe Leu Pro Ile Ile His Ile Pro Leu Arg His Leu Ser 
1               5                   10                  15


Ile Gln Arg Thr Val Ile Asn Ala Val Gly Val Gln Asp Ile Ile Ser 
            20                  25                  30


Val Phe Lys Val Leu Val Ser Cys Asp Ser Met Thr Phe Cys Tyr Ser 
        35                  40                  45


His Ser Arg Glu Val Arg Lys Gly Leu Met Met Glu Lys Gly Cys Asn 
    50                  55                  60


Arg Leu Leu Ala 
65


<210>  6338
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  6338
ggttcagaaa ctgttgtcat gtctaacttt tggtgattgg tttgtacaaa cttatgtctt     60

gtttatggat atgtataatt tgaatgtaag aagagttcct gttggtgttg gtgggtggaa    120

catggaggaa cacagagttc ttgcaaactc actttttctt gcctctttgg tgtcttttaa    180

gccaacccat gactggctgt gccagtacag tgtggttacc agactgagaa gatatttgca    240

ggaactagga gacagagggt ataaggagaa agcaaacaat gggcagtgtt ggaaacttaa    300

attccaattg tgactgtcac tgtcttgcgt gtgatgttgg ataagcccca tttcctctct    360

gggtctcatt tccccattga taaaacatgg ttaataatat ggtgctattt ccttcagaaa    420

attgcttggt ggtcaaaatg agataaagga tgctaaagaa ttttgtaaat taaaaagtga    480

taaaggctta gagaaccttc ttcatacctt actaagttca agttgctact tagcaatgtt    540

ttcctttttc ttaatgctgt ctctcccaag gagttctcac agagcccagc cagtagcaca    600

cattagtgat ggtttcctgc tcttcccctc ttagaataat aaagggtctc cccatgt       657


<210>  6339
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  6339

Met Asp Met Tyr Asn Leu Asn Val Arg Arg Val Pro Val Gly Val Gly 
1               5                   10                  15


Gly Trp Asn Met Glu Glu His Arg Val Leu Ala Asn Ser Leu Phe Leu 
            20                  25                  30


Ala Ser Leu Val Ser Phe Lys Pro Thr His Asp Trp Leu Cys Gln Tyr 
        35                  40                  45


Ser Val Val Thr Arg Leu Arg Arg Tyr Leu Gln Glu Leu Gly Asp Arg 
    50                  55                  60


Gly Tyr Lys Glu Lys Ala Asn Asn Gly Gln Cys Trp Lys Leu Lys Phe 
65                  70                  75                  80


Gln Leu 



<210>  6340
<211>  4934
<212>  DNA
<213>  Homo sapiens

<400>  6340
tgaaactccc tagattttac tgtataatgt caatggactc attatttgta caacagctga     60

tgtatttagg acttgttgat tcacttaatt ggtaactgta ctacattcat aacttcaaca    120

actgaaaaca ataggtcagt gtctgctgtt tatgcataaa tagtcacatc ggagcaggat    180

atgtctgaat ggcagaatat gttagtctga ggaggaatct ggcatgtgaa tggctccatt    240

gcttgccata ctgagatcct gaggtgcaga ggcaattccc ggaggactac agtgaccagg    300

aagttctaca gactttgacc aagttttgtt tccccttcta tgtggacagc ctcacagtta    360

gccaagttgg ccagaacttc acattcgtgc tcactgacat tgacagcaaa cagagattcg    420

ggttctgccg cttatcttca ggagcgaaga gctgcttctg tatcttaagg aaaatcagtg    480

gaatgagctt cttgaaactc tgcacaaact tcccatccct gacccaggag tgtctgtcca    540

tctcagcgtg cattcttatt ttactgtgcc tgataccaga gaacttccca gcatacctga    600

gaatagaaat ctgacagaat attttgtggc tgtggatgtt aacaacatgt tgcatctgta    660

cgccagtatg ctgtacgaac gccggatact catcatttgc agcaaactca gcactctgac    720

tgcctgcatc cacgggtctg cggcgatgct ctaccccatg tactggcagc acgtgtacat    780

ccccgtgctg ccgccgcatc tgctggacta ctgctgtgct cccatgccct acctcatagg    840

aatccattta agtttaatgg agaaagtcag aaacatggcc ctggatgatg tcgtgatcct    900

gaatgtggac accaacaccc tggaaacccc cttcgatgac ctccagagcc tcccaaacga    960

cgtgatctct tccctgaaga acaggctgaa aaaggtctcc acaaccactg gggatggtgt   1020

ggccagagcg ttcctcaagg cccaggctgc tttcttcggt agctaccgaa acgctctgaa   1080

aatcgagccg aaaggaagtg gagcaattct gaatactgta aagaccaaag caaatccggc   1140

catgaagact gtctacaagt tcgcaaaaga tcatgcaaaa atgggaataa aagaggtgaa   1200

aaaccgcttg aagcaaaagg acattgccga gaatggctgc gcccccaccc cagaagagca   1260

gctgccaaag actgcaccgt ccccactggt ggaggccaag gaccccaagc tccgagaaga   1320

ccggcggcca atcacagtcc actttggaca ggtgcgccca cctcgtccac atgttgttaa   1380

gagaccaaag agcaacatcg cagtggaagg ccggaggacg tctgtgccga gccctgagca   1440

cctggtaaag cccttgcgac actatgcggt cttcctctcc gaagactcct ctgatgatga   1500

atgccagcgg gaagagggcc cgagctctgg cttcaccgag agctttttct tctccgctcc   1560

ctttgaatgg ccgcagccgt atcggacact cagggagtca gacagcgcgg aaggcgacga   1620

ggcagagagt ccagagcagc aagtgcggaa gtccacaggc cctgtcccag ctccccctga   1680

ccgggctgcc agcatcgacc ttctggaaga cgtcttcagc aacctggaca tggaggccgc   1740

actgcagcca ctgggccagg ccaagagctt agaggacctt cgtgccccca aagacctgag   1800

ggagcagcca gggacctttg actatcagag gctggatctg ggcgggagtg agaggagccg   1860

cggggtgaca gtggccttga agcttaccca cccgtacaac aagctctgga gcctgggcca   1920

ggacgacatg gccatcccca gcaagccccc agctgcctcc cctgagaagc cctcagccct   1980

gctcggaaac tccctggccc tgcctcgaag gccccagaac cgggacagca tcctgaaccc   2040

cagtgacaag gaggaggtgc ccacccctac tctgggcagc atcaccatcc cccggcccca   2100

aggcaggaag accccagagc tgggcatcgt gcctccaccg cccattcccc gcccggccaa   2160

gctccaggct gccggcgccg cacttggtga cgtctcagag cggctgcaga cggatcggga   2220

caggcgagct gccctgagtc cagggctcct gcctggtgtt gtcccccaag gccccactga   2280

actgctccag ccgctcagcc ctggccccgg ggctgcaggc acgagcagtg acgccctgct   2340

cgccctcctg gacccgctca gcacagcctg gtcaggcagc accctcccgt cacgccccgc   2400

caccccgaat gtagccaccc cattcacccc ccaattcagc ttcccccctg cagggacacc   2460

caccccattc ccacagccac cactcaaccc ctttgtccca tccatgccag cagccccacc   2520

caccctgccc ctggtctcca caccagccgg gcctttcggg gcccctccag cttccctggg   2580

gccggctttt gcgtccggcc tcctgctgtc cagtgctggc ttctgtgccc ctcacaggtc   2640

tcagcccaac ctctccgccc tctccatgcc caacctcttt ggccagatgc ccatgggcac   2700

ccacacgagc cccctacagc cgctgggtcc cccagcagtt gccccgtcga ggatccgaac   2760

gttgcccctg gcccgctcaa gtgccagggc tgctgagacc aagcaggggc tggccctgag   2820

gcctggagac cccccgcttc tgcctcccag gccccctcaa ggcctggagc caacactgca   2880

gccctctgct cctcaacagg ccagagaccc ctttgaggat ttgttacaga aaaccaagca   2940

agacgtgagc ccgagtccgg ccctggcccc ggccccagac tcggtggagc agctcaggaa   3000

gcagtgggag accttcgagt gagccgggcc ctgagggtgg gggatgcacc gaggcccgag   3060

ggtccgtcca ctgctgcggt tccgaggctc ccccgccact ctctctctgc ccaggttctg   3120

ctggtgggaa gggatgggac ccctctctgc tgccccctcc tcccctccac actgcccatc   3180

tctgatgtct ggccctgggg aatggcacca gttccagcct gggaatcaac ccagttcctg   3240

agtgcccatc ccaccccgcg gttgcctctc ctcggcaccc ttgattgggt tttgcactaa   3300

agaggtcagc tgggccaatg atattgctcc agaccgagtc ctacccacct tcccccggaa   3360

gtgtcccaag aggctccgaa ggcctcccct ccgagcccag ctctcctgtc tcctccacag   3420

ccaggccctg cacgcccacc tcctcggaca caggtgacag ggttaccctc cagtttgagc   3480

tcatctgcac gagacacagg tagcttgggg ttgaagttag gactcctcct gggctggagg   3540

atttacctgg tggggcactt ccagactgtt tctagcaata tacacacacg ttctttcctg   3600

tgtcttcacc ccaaaacttc agttgattct gacctgggag gatctgggga ccagggggtc   3660

ttgggctgcc ttgtgataca cagccccagc caccctgcac gggggctgcg agcaccagca   3720

actttgattt atagaaggaa aatggaaacc cccatctgag tattttggga ggagccccca   3780

gccctcatcc agctctggca cgctgatacc tccaggtact cccctcactg tcaaagctgg   3840

ggctcagcct cttgtcatct ggagctttgt gggcaaagct gagaagctgc aacccagatt   3900

tcaacccaaa aaggtcaagc tgaatgcctc agactgatgt ggaaggcagc tggccttcct   3960

gggttggaac gaggcagtgg ccctgagccc cttctccagg gccaggtaga aaggacaaac   4020

ttggtctctg cctcggggaa gcaggaggag ggctagaagc cagtccctcc ccacctgccc   4080

agagctccag gccagcacag aaattcctga ggccaacgtc accaaagtta gattgaatgt   4140

ttattatctt tctttttcct ttttacctta ttgatttgat gaatcttgaa atggattcat   4200

ttccataaac caagttaaag tatggcccga ccatttaaga aaacaaccat ctgagacacg   4260

caggaaattg tgagcatttc gacccgagct ctcatttcct atttgtgaag ggtcagacac   4320

agtctaccca ggggtgtctg ggggacaagg gggtctctgg agatgtcacc cagggagccc   4380

cctctatgtc tgagaggctg ccactgctgc acatgctcag tgaggcttgg cggccatcct   4440

ggcacatggc tcttcctggg tcaaccgtga cctgtctggc tcaggaatgg gctctggctg   4500

ctgggggagc cgtgtcactc ctgggccatg ggggcacctc ctgggcactt aggtgtttca   4560

gcatagattc cagtttcgca ccctgggcag acccccaggc cccatccggg atagggcaga   4620

ggaggtgctg gcggccccag ggaaggaggg tgtgtacccc aaggccccct ggctgtgctg   4680

aggggctggg gtgagcgctc catgttcaca tgagcactgc tgcctcttca cttgtgggac   4740

tttttgcaaa cccaaggatg aactttgtgt gcattcaata aaatcatctt ggggaagagg   4800

ctggcatccc cgtgtccttg aagcttttgg gtcggggagg ccccacacgg gcccggagcc   4860

atcctcacca cctgctcctg tagaggcagg ggccaggcgc agagcagtta gggaaggagt   4920

caactccccg cacc                                                     4934


<210>  6341
<211>  791
<212>  PRT
<213>  Homo sapiens

<400>  6341

Met Leu His Leu Tyr Ala Ser Met Leu Tyr Glu Arg Arg Ile Leu Ile 
1               5                   10                  15


Ile Cys Ser Lys Leu Ser Thr Leu Thr Ala Cys Ile His Gly Ser Ala 
            20                  25                  30


Ala Met Leu Tyr Pro Met Tyr Trp Gln His Val Tyr Ile Pro Val Leu 
        35                  40                  45


Pro Pro His Leu Leu Asp Tyr Cys Cys Ala Pro Met Pro Tyr Leu Ile 
    50                  55                  60


Gly Ile His Leu Ser Leu Met Glu Lys Val Arg Asn Met Ala Leu Asp 
65                  70                  75                  80


Asp Val Val Ile Leu Asn Val Asp Thr Asn Thr Leu Glu Thr Pro Phe 
                85                  90                  95


Asp Asp Leu Gln Ser Leu Pro Asn Asp Val Ile Ser Ser Leu Lys Asn 
            100                 105                 110


Arg Leu Lys Lys Val Ser Thr Thr Thr Gly Asp Gly Val Ala Arg Ala 
        115                 120                 125


Phe Leu Lys Ala Gln Ala Ala Phe Phe Gly Ser Tyr Arg Asn Ala Leu 
    130                 135                 140


Lys Ile Glu Pro Lys Gly Ser Gly Ala Ile Leu Asn Thr Val Lys Thr 
145                 150                 155                 160


Lys Ala Asn Pro Ala Met Lys Thr Val Tyr Lys Phe Ala Lys Asp His 
                165                 170                 175


Ala Lys Met Gly Ile Lys Glu Val Lys Asn Arg Leu Lys Gln Lys Asp 
            180                 185                 190


Ile Ala Glu Asn Gly Cys Ala Pro Thr Pro Glu Glu Gln Leu Pro Lys 
        195                 200                 205


Thr Ala Pro Ser Pro Leu Val Glu Ala Lys Asp Pro Lys Leu Arg Glu 
    210                 215                 220


Asp Arg Arg Pro Ile Thr Val His Phe Gly Gln Val Arg Pro Pro Arg 
225                 230                 235                 240


Pro His Val Val Lys Arg Pro Lys Ser Asn Ile Ala Val Glu Gly Arg 
                245                 250                 255


Arg Thr Ser Val Pro Ser Pro Glu His Leu Val Lys Pro Leu Arg His 
            260                 265                 270


Tyr Ala Val Phe Leu Ser Glu Asp Ser Ser Asp Asp Glu Cys Gln Arg 
        275                 280                 285


Glu Glu Gly Pro Ser Ser Gly Phe Thr Glu Ser Phe Phe Phe Ser Ala 
    290                 295                 300


Pro Phe Glu Trp Pro Gln Pro Tyr Arg Thr Leu Arg Glu Ser Asp Ser 
305                 310                 315                 320


Ala Glu Gly Asp Glu Ala Glu Ser Pro Glu Gln Gln Val Arg Lys Ser 
                325                 330                 335


Thr Gly Pro Val Pro Ala Pro Pro Asp Arg Ala Ala Ser Ile Asp Leu 
            340                 345                 350


Leu Glu Asp Val Phe Ser Asn Leu Asp Met Glu Ala Ala Leu Gln Pro 
        355                 360                 365


Leu Gly Gln Ala Lys Ser Leu Glu Asp Leu Arg Ala Pro Lys Asp Leu 
    370                 375                 380


Arg Glu Gln Pro Gly Thr Phe Asp Tyr Gln Arg Leu Asp Leu Gly Gly 
385                 390                 395                 400


Ser Glu Arg Ser Arg Gly Val Thr Val Ala Leu Lys Leu Thr His Pro 
                405                 410                 415


Tyr Asn Lys Leu Trp Ser Leu Gly Gln Asp Asp Met Ala Ile Pro Ser 
            420                 425                 430


Lys Pro Pro Ala Ala Ser Pro Glu Lys Pro Ser Ala Leu Leu Gly Asn 
        435                 440                 445


Ser Leu Ala Leu Pro Arg Arg Pro Gln Asn Arg Asp Ser Ile Leu Asn 
    450                 455                 460


Pro Ser Asp Lys Glu Glu Val Pro Thr Pro Thr Leu Gly Ser Ile Thr 
465                 470                 475                 480


Ile Pro Arg Pro Gln Gly Arg Lys Thr Pro Glu Leu Gly Ile Val Pro 
                485                 490                 495


Pro Pro Pro Ile Pro Arg Pro Ala Lys Leu Gln Ala Ala Gly Ala Ala 
            500                 505                 510


Leu Gly Asp Val Ser Glu Arg Leu Gln Thr Asp Arg Asp Arg Arg Ala 
        515                 520                 525


Ala Leu Ser Pro Gly Leu Leu Pro Gly Val Val Pro Gln Gly Pro Thr 
    530                 535                 540


Glu Leu Leu Gln Pro Leu Ser Pro Gly Pro Gly Ala Ala Gly Thr Ser 
545                 550                 555                 560


Ser Asp Ala Leu Leu Ala Leu Leu Asp Pro Leu Ser Thr Ala Trp Ser 
                565                 570                 575


Gly Ser Thr Leu Pro Ser Arg Pro Ala Thr Pro Asn Val Ala Thr Pro 
            580                 585                 590


Phe Thr Pro Gln Phe Ser Phe Pro Pro Ala Gly Thr Pro Thr Pro Phe 
        595                 600                 605


Pro Gln Pro Pro Leu Asn Pro Phe Val Pro Ser Met Pro Ala Ala Pro 
    610                 615                 620


Pro Thr Leu Pro Leu Val Ser Thr Pro Ala Gly Pro Phe Gly Ala Pro 
625                 630                 635                 640


Pro Ala Ser Leu Gly Pro Ala Phe Ala Ser Gly Leu Leu Leu Ser Ser 
                645                 650                 655


Ala Gly Phe Cys Ala Pro His Arg Ser Gln Pro Asn Leu Ser Ala Leu 
            660                 665                 670


Ser Met Pro Asn Leu Phe Gly Gln Met Pro Met Gly Thr His Thr Ser 
        675                 680                 685


Pro Leu Gln Pro Leu Gly Pro Pro Ala Val Ala Pro Ser Arg Ile Arg 
    690                 695                 700


Thr Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala Ala Glu Thr Lys Gln 
705                 710                 715                 720


Gly Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu Leu Pro Pro Arg Pro 
                725                 730                 735


Pro Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser Ala Pro Gln Gln Ala 
            740                 745                 750


Arg Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr Lys Gln Asp Val Ser 
        755                 760                 765


Pro Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser Val Glu Gln Leu Arg 
    770                 775                 780


Lys Gln Trp Glu Thr Phe Glu 
785                 790


<210>  6342
<211>  2515
<212>  DNA
<213>  Homo sapiens

<400>  6342
ttcgccgggc tggagcgagt acattaaccc ctggaggcgg cggcggcggc gagggagcga     60

gcctcgagcg ggcgggcccc agccatgcca gcagccccac ccaccctgcc cctggtctcc    120

acaccagccg ggcctttcgg ggcccctcca gcttccctgg ggccggcttt tgcgtccggc    180

ctcctgctgt ccagtgctgg cttctgtgcc cctcacaggt ctcagcccaa cctctccgcc    240

ctctccatgc ccaacctctt tggccagatg cccatgggca cccacacgag ccccctacag    300

ccgctgggtc ccccagcagt tgccccgtcg aggatccgaa cgttgcccct ggcccgctca    360

agtgccaggg ctgctgagac caagcagggg ctggccctga ggcctggaga ccccccgctt    420

ctgcctccca ggccccctca aggcctggag ccaacactgc agccctctgc tcctcaacag    480

gccagagacc cctttgagga tttgttacag aaaaccaagc aagacgtgag cccgagtccg    540

gccctggccc cggccccaga ctcggtggag cagctcagga agcagtggga gaccttcgag    600

tgagccgggc cctgagggtg ggggatgcac cgaggcccga gggtccgtcc actgctgcgg    660

ttccgaggct cccccgccac tctctctctg cccaggttct gctggtggga agggatggga    720

cccctctctg ctgccccctc ctcccctcca cactgcccat ctctgatgtc tggccctggg    780

gaatggcacc agttccagcc tgggaatcaa cccagttcct gagtgcccat cccaccccgc    840

ggttgcctct cctcggcacc cttgattggg ttttgcacta aagaggtcag ctgggccaat    900

gatattgctc cagaccgagt cctacccacc ttcccccgga agtgtcccaa gaggctccga    960

aggcctcccc tccgagccca gctctcctgt ctcctccaca gccaggccct gcacgcccac   1020

ctcctcggac acaggtgaca gggttaccct ccagtttgag ctcatctgca cgagacacag   1080

gtagcttggg gttgaagtta ggactcctcc tgggctggag gatttacctg gtggggcact   1140

tccagactgt ttctagcaat atacacacac gttctttcct gtgtcttcac cccaaaactt   1200

cagttgattc tgacctggga ggatctgggg accagggggt cttgggctgc cttgtgatac   1260

acagccccag ccaccctgca cgggggctgc gagcaccagc aactttgatt tatagaagga   1320

aaatggaaac ccccatctga gtattttggg aggagccccc agccctcatc cagctctggc   1380

acgctgatac ctccaggtac tcccctcact gtcaaagctg gggctcagcc tcttgtcatc   1440

tggagctttg tgggcaaagc tgagaagctg caacccagat ttcaacccaa aaaggtcaag   1500

ctgaatgcct cagactgatg tggaaggcag ctggccttcc tgggttggaa cgaggcagtg   1560

gccctgagcc ccttctccag ggccaggtag aaaggacaaa cttggtctct gcctcgggga   1620

agcaggagga gggctagaag ccagtccctc cccacctgcc cagagctcca ggccagcaca   1680

gaaattcctg aggccaacgt caccaaagtt agattgaatg tttattatct ttctttttcc   1740

tttttacctt attgatttga tgaatcttga aatggattca tttccataaa ccaagttaaa   1800

gtatggcccg accatttaag aaaacaacca tctgagacac gcaggaaatt gtgagcattt   1860

cgacccgagc tctcatttcc tatttgtgaa gggtcagaca cagtctaccc aggggtgtct   1920

gggggacaag ggggtctctg gagatgtcac ccagggagcc ccctctatgt ctgagaggct   1980

gccactgctg cacatgctca gtgaggcttg gcggccatcc tggcacatgg ctcttcctgg   2040

gtcaaccgtg acctgtctgg ctcaggaatg ggctctggct gctgggggag ccgtgtcact   2100

cctgggccat gggggcacct cctgggcact taggtgtttc agcatagatt ccagtttcgc   2160

accctgggca gacccccagg ccccatccgg gatagggcag aggaggtgct ggcggcccca   2220

gggaaggagg gtgtgtaccc caaggccccc tggctgtgct gaggggctgg ggtgagcgct   2280

ccatgttcac atgagcactg ctgcctcttc acttgtggga ctttttgcaa acccaaggat   2340

gaactttgtg tgcattcaat aaaatcatct tggggaagag gctggcatcc ccgtgtcctt   2400

gaagcttttg ggtcggggag gccccacacg ggcccggagc catcctcacc acctgctcct   2460

gtagaggcag gggccaggcg cagagcagtt agggaaggag tcaactcccc gcacc        2515


<210>  6343
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  6343

Met Pro Ala Ala Pro Pro Thr Leu Pro Leu Val Ser Thr Pro Ala Gly 
1               5                   10                  15


Pro Phe Gly Ala Pro Pro Ala Ser Leu Gly Pro Ala Phe Ala Ser Gly 
            20                  25                  30


Leu Leu Leu Ser Ser Ala Gly Phe Cys Ala Pro His Arg Ser Gln Pro 
        35                  40                  45


Asn Leu Ser Ala Leu Ser Met Pro Asn Leu Phe Gly Gln Met Pro Met 
    50                  55                  60


Gly Thr His Thr Ser Pro Leu Gln Pro Leu Gly Pro Pro Ala Val Ala 
65                  70                  75                  80


Pro Ser Arg Ile Arg Thr Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala 
                85                  90                  95


Ala Glu Thr Lys Gln Gly Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu 
            100                 105                 110


Leu Pro Pro Arg Pro Pro Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser 
        115                 120                 125


Ala Pro Gln Gln Ala Arg Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr 
    130                 135                 140


Lys Gln Asp Val Ser Pro Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser 
145                 150                 155                 160


Val Glu Gln Leu Arg Lys Gln Trp Glu Thr Phe Glu 
                165                 170


<210>  6344
<211>  2397
<212>  DNA
<213>  Homo sapiens

<400>  6344
ttcgccgggc tggagcgagt acattaaccc ctggaggcgg cggcggcggc gagggagcga     60

gcctcgagcg ggcgggcccc agcttctgtg cccctcacag gtctcagccc aacctctccg    120

ccctctccat gcccaacctc tttggccaga tgcccatggg cacccacacg agccccctac    180

agccgctggg tcccccagca gttgccccgt cgaggatccg aacgttgccc ctggcccgct    240

caagtgccag ggctgctgag accaagcagg ggctggccct gaggcctgga gaccccccgc    300

ttctgcctcc caggccccct caaggcctgg agccaacact gcagccctct gctcctcaac    360

aggccagaga cccctttgag gatttgttac agaaaaccaa gcaagacgtg agcccgagtc    420

cggccctggc cccggcccca gactcggtgg agcagctcag gaagcagtgg gagaccttcg    480

agtgagccgg gccctgaggg tgggggatgc accgaggccc gagggtccgt ccactgctgc    540

ggttccgagg ctcccccgcc actctctctc tgcccaggtt ctgctggtgg gaagggatgg    600

gacccctctc tgctgccccc tcctcccctc cacactgccc atctctgatg tctggccctg    660

gggaatggca ccagttccag cctgggaatc aacccagttc ctgagtgccc atcccacccc    720

gcggttgcct ctcctcggca cccttgattg ggttttgcac taaagaggtc agctgggcca    780

atgatattgc tccagaccga gtcctaccca ccttcccccg gaagtgtccc aagaggctcc    840

gaaggcctcc cctccgagcc cagctctcct gtctcctcca cagccaggcc ctgcacgccc    900

acctcctcgg acacaggtga cagggttacc ctccagtttg agctcatctg cacgagacac    960

aggtagcttg gggttgaagt taggactcct cctgggctgg aggatttacc tggtggggca   1020

cttccagact gtttctagca atatacacac acgttctttc ctgtgtcttc accccaaaac   1080

ttcagttgat tctgacctgg gaggatctgg ggaccagggg gtcttgggct gccttgtgat   1140

acacagcccc agccaccctg cacgggggct gcgagcacca gcaactttga tttatagaag   1200

gaaaatggaa acccccatct gagtattttg ggaggagccc ccagccctca tccagctctg   1260

gcacgctgat acctccaggt actcccctca ctgtcaaagc tggggctcag cctcttgtca   1320

tctggagctt tgtgggcaaa gctgagaagc tgcaacccag atttcaaccc aaaaaggtca   1380

agctgaatgc ctcagactga tgtggaaggc agctggcctt cctgggttgg aacgaggcag   1440

tggccctgag ccccttctcc agggccaggt agaaaggaca aacttggtct ctgcctcggg   1500

gaagcaggag gagggctaga agccagtccc tccccacctg cccagagctc caggccagca   1560

cagaaattcc tgaggccaac gtcaccaaag ttagattgaa tgtttattat ctttcttttt   1620

cctttttacc ttattgattt gatgaatctt gaaatggatt catttccata aaccaagtta   1680

aagtatggcc cgaccattta agaaaacaac catctgagac acgcaggaaa ttgtgagcat   1740

ttcgacccga gctctcattt cctatttgtg aagggtcaga cacagtctac ccaggggtgt   1800

ctgggggaca agggggtctc tggagatgtc acccagggag ccccctctat gtctgagagg   1860

ctgccactgc tgcacatgct cagtgaggct tggcggccat cctggcacat ggctcttcct   1920

gggtcaaccg tgacctgtct ggctcaggaa tgggctctgg ctgctggggg agccgtgtca   1980

ctcctgggcc atgggggcac ctcctgggca cttaggtgtt tcagcataga ttccagtttc   2040

gcaccctggg cagaccccca ggccccatcc gggatagggc agaggaggtg ctggcggccc   2100

cagggaagga gggtgtgtac cccaaggccc cctggctgtg ctgaggggct ggggtgagcg   2160

ctccatgttc acatgagcac tgctgcctct tcacttgtgg gactttttgc aaacccaagg   2220

atgaactttg tgtgcattca ataaaatcat cttggggaag aggctggcat ccccgtgtcc   2280

ttgaagcttt tgggtcgggg aggccccaca cgggcccgga gccatcctca ccacctgctc   2340

ctgtagaggc aggggccagg cgcagagcag ttagggaagg agtcaactcc ccgcacc      2397


<210>  6345
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  6345

Met Pro Asn Leu Phe Gly Gln Met Pro Met Gly Thr His Thr Ser Pro 
1               5                   10                  15


Leu Gln Pro Leu Gly Pro Pro Ala Val Ala Pro Ser Arg Ile Arg Thr 
            20                  25                  30


Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala Ala Glu Thr Lys Gln Gly 
        35                  40                  45


Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu Leu Pro Pro Arg Pro Pro 
    50                  55                  60


Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser Ala Pro Gln Gln Ala Arg 
65                  70                  75                  80


Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr Lys Gln Asp Val Ser Pro 
                85                  90                  95


Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser Val Glu Gln Leu Arg Lys 
            100                 105                 110


Gln Trp Glu Thr Phe Glu 
        115


<210>  6346
<211>  5175
<212>  DNA
<213>  Homo sapiens

<400>  6346
cgcgcgccgg gcacgcgcgc cggcgaccat ggcgttcgcc gggctggagc gagtacatta     60

acccctggag gcggcggcgg cggcgaggga gcgagcctcg agcgggcggg ccccagcctg    120

agggaaggga ggaaggggcg gggagagcgc cagagggagg ccggtcggcc gcgggcgggc    180

gggcagcgca gcgccgagcg gggcccgcgg gcccatgagg aggcctgggg accatgggct    240

ccaggatcaa gcagaatcca gagaccacat ttgaagtata tgttgaagtg gcctatccca    300

ggacaggtgg cactctttca gatcctgagg tgcagaggca attcccggag gactacagtg    360

accaggaagt tctacagact ttgaccaagt tttgtttccc cttctatgtg gacagcctca    420

cagttagcca agttggccag aacttcacat tcgtgctcac tgacattgac agcaaacaga    480

gattcgggtt ctgccgctta tcttcaggag cgaagagctg cttctgtatc ttaagctatc    540

tcccctggtt cgaggtattt tataagctgc ttaacatcct ggcagattac acgacaaaaa    600

gacaggaaaa tcagtggaat gagcttcttg aaactctgca caaacttccc atccctgacc    660

caggagtgtc tgtccatctc agcgtgcatt cttattttac tgtgcctgat accagagaac    720

ttcccagcat acctgagaat agaaatctga cagaatattt tgtggctgtg gatgttaaca    780

acatgttgca tctgtacgcc agtatgctgt acgaacgccg gatactcatc atttgcagca    840

aactcagcac tctgactgcc tgcatccacg ggtctgcggc gatgctctac cccatgtact    900

ggcagcacgt gtacatcccc gtgctgccgc cgcatctgct ggactactgc tgtgctccca    960

tgccctacct cataggaatc catttaagtt taatggagaa agtcagaaac atggccctgg   1020

atgatgtcgt gatcctgaat gtggacacca acaccctgga aacccccttc gatgacctcc   1080

agagcctccc aaacgacgtg atctcttccc tgaagaacag gctgaaaaag gtctccacaa   1140

ccactgggga tggtgtggcc agagcgttcc tcaaggccca ggctgctttc ttcggtagct   1200

accgaaacgc tctgaaaatc gagccggagg agccgatcac tttctgtgag gaagccttcg   1260

tgtcccacta ccgctccgga gccatgaggc agttcctgca gaacgccaca cagctgcagc   1320

tcttcaagca gtttattgat ggtcgattag atcttctcaa ttccggcgaa ggtttcagtg   1380

atgtttttga agaggaaatc aacatgggcg agtacgctgg cagtgacaaa ctgtaccatc   1440

agtggctctc cactgtccgg aaaggaagtg gagcaattct gaatactgta aagaccaaag   1500

caaatccggc catgaagact gtctacaagt tcgcaaaaga tcatgcaaaa atgggaataa   1560

aagaggtgaa aaaccgcttg aagcaaaagg acattgccga gaatggctgc gcccccaccc   1620

cagaagagca gctgccaaag actgcaccgt ccccactggt ggaggccaag gaccccaagc   1680

tccgagaaga ccggcggcca atcacagtcc actttggaca ggtgcgccca cctcgtccac   1740

atgttgttaa gagaccaaag agcaacatcg cagtggaagg ccggaggacg tctgtgccga   1800

gccctgagca gccgcagccg tatcggacac tcagggagtc agacagcgcg gaaggcgacg   1860

aggcagagag tccagagcag caagtgcgga agtccacagg ccctgtccca gctccccctg   1920

accgggctgc cagcatcgac cttctggaag acgtcttcag caacctggac atggaggccg   1980

cactgcagcc actgggccag gccaagagct tagaggacct tcgtgccccc aaagacctga   2040

gggagcagcc agggaccttt gactatcaga ggctggatct gggcgggagt gagaggagcc   2100

gcggggtgac agtggccttg aagcttaccc acccgtacaa caagctctgg agcctgggcc   2160

aggacgacat ggccatcccc agcaagcccc cagctgcctc ccctgagaag ccctcagccc   2220

tgctcggaaa ctccctggcc ctgcctcgaa ggccccagaa ccgggacagc atcctgaacc   2280

ccagtgacaa ggaggaggtg cccaccccta ctctgggcag catcaccatc ccccggcccc   2340

aaggcaggaa gaccccagag ctgggcatcg tgcctccacc gcccattccc cgcccggcca   2400

agctccaggc tgccggcgcc gcacttggtg acgtctcaga gcggctgcag acggatcggg   2460

acaggcgagc tgccctgagt ccagggctcc tgcctggtgt tgtcccccaa ggccccactg   2520

aactgctcca gccgctcagc cctggccccg gggctgcagg cacgagcagt gacgccctgc   2580

tcgccctcct ggacccgctc agcacagcct ggtcaggcag caccctcccg tcacgccccg   2640

ccaccccgaa tgtagccacc ccattcaccc cccaattcag cttcccccct gcagggacac   2700

ccaccccatt cccacagcca ccactcaacc cctttgtccc atccatgcca gcagccccac   2760

ccaccctgcc cctggtctcc acaccagccg ggcctttcgg ggcccctcca gcttccctgg   2820

ggccggcttt tgcgtccggc ctcctgctgt ccagtgctgg cttctgtgcc cctcacaggt   2880

ctcagcccaa cctctccgcc ctctccatgc ccaacctctt tggccagatg cccatgggca   2940

cccacacgag ccccctacag ccgctgggtc ccccagcagt tgccccgtcg aggatccgaa   3000

cgttgcccct ggcccgctca agtgccaggg ctgctgagac caagcagggg ctggccctga   3060

ggcctggaga ccccccgctt ctgcctccca ggccccctca aggcctggag ccaacactgc   3120

agccctctgc tcctcaacag gccagagacc cctttgagga tttgttacag aaaaccaagc   3180

aagacgtgag cccgagtccg gccctggccc cggccccaga ctcggtggag cagctcagga   3240

agcagtggga gaccttcgag tgagccgggc cctgagggtg ggggatgcac cgaggcccga   3300

gggtccgtcc actgctgcgg ttccgaggct cccccgccac tctctctctg cccaggttct   3360

gctggtggga agggatggga cccctctctg ctgccccctc ctcccctcca cactgcccat   3420

ctctgatgtc tggccctggg gaatggcacc agttccagcc tgggaatcaa cccagttcct   3480

gagtgcccat cccaccccgc ggttgcctct cctcggcacc cttgattggg ttttgcacta   3540

aagaggtcag ctgggccaat gatattgctc cagaccgagt cctacccacc ttcccccgga   3600

agtgtcccaa gaggctccga aggcctcccc tccgagccca gctctcctgt ctcctccaca   3660

gccaggccct gcacgcccac ctcctcggac acaggtgaca gggttaccct ccagtttgag   3720

ctcatctgca cgagacacag gtagcttggg gttgaagtta ggactcctcc tgggctggag   3780

gatttacctg gtggggcact tccagactgt ttctagcaat atacacacac gttctttcct   3840

gtgtcttcac cccaaaactt cagttgattc tgacctggga ggatctgggg accagggggt   3900

cttgggctgc cttgtgatac acagccccag ccaccctgca cgggggctgc gagcaccagc   3960

aactttgatt tatagaagga aaatggaaac ccccatctga gtattttggg aggagccccc   4020

agccctcatc cagctctggc acgctgatac ctccaggtac tcccctcact gtcaaagctg   4080

gggctcagcc tcttgtcatc tggagctttg tgggcaaagc tgagaagctg caacccagat   4140

ttcaacccaa aaaggtcaag ctgaatgcct cagactgatg tggaaggcag ctggccttcc   4200

tgggttggaa cgaggcagtg gccctgagcc ccttctccag ggccaggtag aaaggacaaa   4260

cttggtctct gcctcgggga agcaggagga gggctagaag ccagtccctc cccacctgcc   4320

cagagctcca ggccagcaca gaaattcctg aggccaacgt caccaaagtt agattgaatg   4380

tttattatct ttctttttcc tttttacctt attgatttga tgaatcttga aatggattca   4440

tttccataaa ccaagttaaa gtatggcccg accatttaag aaaacaacca tctgagacac   4500

gcaggaaatt gtgagcattt cgacccgagc tctcatttcc tatttgtgaa gggtcagaca   4560

cagtctaccc aggggtgtct gggggacaag ggggtctctg gagatgtcac ccagggagcc   4620

ccctctatgt ctgagaggct gccactgctg cacatgctca gtgaggcttg gcggccatcc   4680

tggcacatgg ctcttcctgg gtcaaccgtg acctgtctgg ctcaggaatg ggctctggct   4740

gctgggggag ccgtgtcact cctgggccat gggggcacct cctgggcact taggtgtttc   4800

agcatagatt ccagtttcgc accctgggca gacccccagg ccccatccgg gatagggcag   4860

aggaggtgct ggcggcccca gggaaggagg gtgtgtaccc caaggccccc tggctgtgct   4920

gaggggctgg ggtgagcgct ccatgttcac atgagcactg ctgcctcttc acttgtggga   4980

ctttttgcaa acccaaggat gaactttgtg tgcattcaat aaaatcatct tggggaagag   5040

gctggcatcc ccgtgtcctt gaagcttttg ggtcggggag gccccacacg ggcccggagc   5100

catcctcacc acctgctcct gtagaggcag gggccaggcg cagagcagtt agggaaggag   5160

tcaactcccc gcacc                                                    5175


<210>  6347
<211>  1009
<212>  PRT
<213>  Homo sapiens

<400>  6347

Met Gly Ser Arg Ile Lys Gln Asn Pro Glu Thr Thr Phe Glu Val Tyr 
1               5                   10                  15


Val Glu Val Ala Tyr Pro Arg Thr Gly Gly Thr Leu Ser Asp Pro Glu 
            20                  25                  30


Val Gln Arg Gln Phe Pro Glu Asp Tyr Ser Asp Gln Glu Val Leu Gln 
        35                  40                  45


Thr Leu Thr Lys Phe Cys Phe Pro Phe Tyr Val Asp Ser Leu Thr Val 
    50                  55                  60


Ser Gln Val Gly Gln Asn Phe Thr Phe Val Leu Thr Asp Ile Asp Ser 
65                  70                  75                  80


Lys Gln Arg Phe Gly Phe Cys Arg Leu Ser Ser Gly Ala Lys Ser Cys 
                85                  90                  95


Phe Cys Ile Leu Ser Tyr Leu Pro Trp Phe Glu Val Phe Tyr Lys Leu 
            100                 105                 110


Leu Asn Ile Leu Ala Asp Tyr Thr Thr Lys Arg Gln Glu Asn Gln Trp 
        115                 120                 125


Asn Glu Leu Leu Glu Thr Leu His Lys Leu Pro Ile Pro Asp Pro Gly 
    130                 135                 140


Val Ser Val His Leu Ser Val His Ser Tyr Phe Thr Val Pro Asp Thr 
145                 150                 155                 160


Arg Glu Leu Pro Ser Ile Pro Glu Asn Arg Asn Leu Thr Glu Tyr Phe 
                165                 170                 175


Val Ala Val Asp Val Asn Asn Met Leu His Leu Tyr Ala Ser Met Leu 
            180                 185                 190


Tyr Glu Arg Arg Ile Leu Ile Ile Cys Ser Lys Leu Ser Thr Leu Thr 
        195                 200                 205


Ala Cys Ile His Gly Ser Ala Ala Met Leu Tyr Pro Met Tyr Trp Gln 
    210                 215                 220


His Val Tyr Ile Pro Val Leu Pro Pro His Leu Leu Asp Tyr Cys Cys 
225                 230                 235                 240


Ala Pro Met Pro Tyr Leu Ile Gly Ile His Leu Ser Leu Met Glu Lys 
                245                 250                 255


Val Arg Asn Met Ala Leu Asp Asp Val Val Ile Leu Asn Val Asp Thr 
            260                 265                 270


Asn Thr Leu Glu Thr Pro Phe Asp Asp Leu Gln Ser Leu Pro Asn Asp 
        275                 280                 285


Val Ile Ser Ser Leu Lys Asn Arg Leu Lys Lys Val Ser Thr Thr Thr 
    290                 295                 300


Gly Asp Gly Val Ala Arg Ala Phe Leu Lys Ala Gln Ala Ala Phe Phe 
305                 310                 315                 320


Gly Ser Tyr Arg Asn Ala Leu Lys Ile Glu Pro Glu Glu Pro Ile Thr 
                325                 330                 335


Phe Cys Glu Glu Ala Phe Val Ser His Tyr Arg Ser Gly Ala Met Arg 
            340                 345                 350


Gln Phe Leu Gln Asn Ala Thr Gln Leu Gln Leu Phe Lys Gln Phe Ile 
        355                 360                 365


Asp Gly Arg Leu Asp Leu Leu Asn Ser Gly Glu Gly Phe Ser Asp Val 
    370                 375                 380


Phe Glu Glu Glu Ile Asn Met Gly Glu Tyr Ala Gly Ser Asp Lys Leu 
385                 390                 395                 400


Tyr His Gln Trp Leu Ser Thr Val Arg Lys Gly Ser Gly Ala Ile Leu 
                405                 410                 415


Asn Thr Val Lys Thr Lys Ala Asn Pro Ala Met Lys Thr Val Tyr Lys 
            420                 425                 430


Phe Ala Lys Asp His Ala Lys Met Gly Ile Lys Glu Val Lys Asn Arg 
        435                 440                 445


Leu Lys Gln Lys Asp Ile Ala Glu Asn Gly Cys Ala Pro Thr Pro Glu 
    450                 455                 460


Glu Gln Leu Pro Lys Thr Ala Pro Ser Pro Leu Val Glu Ala Lys Asp 
465                 470                 475                 480


Pro Lys Leu Arg Glu Asp Arg Arg Pro Ile Thr Val His Phe Gly Gln 
                485                 490                 495


Val Arg Pro Pro Arg Pro His Val Val Lys Arg Pro Lys Ser Asn Ile 
            500                 505                 510


Ala Val Glu Gly Arg Arg Thr Ser Val Pro Ser Pro Glu Gln Pro Gln 
        515                 520                 525


Pro Tyr Arg Thr Leu Arg Glu Ser Asp Ser Ala Glu Gly Asp Glu Ala 
    530                 535                 540


Glu Ser Pro Glu Gln Gln Val Arg Lys Ser Thr Gly Pro Val Pro Ala 
545                 550                 555                 560


Pro Pro Asp Arg Ala Ala Ser Ile Asp Leu Leu Glu Asp Val Phe Ser 
                565                 570                 575


Asn Leu Asp Met Glu Ala Ala Leu Gln Pro Leu Gly Gln Ala Lys Ser 
            580                 585                 590


Leu Glu Asp Leu Arg Ala Pro Lys Asp Leu Arg Glu Gln Pro Gly Thr 
        595                 600                 605


Phe Asp Tyr Gln Arg Leu Asp Leu Gly Gly Ser Glu Arg Ser Arg Gly 
    610                 615                 620


Val Thr Val Ala Leu Lys Leu Thr His Pro Tyr Asn Lys Leu Trp Ser 
625                 630                 635                 640


Leu Gly Gln Asp Asp Met Ala Ile Pro Ser Lys Pro Pro Ala Ala Ser 
                645                 650                 655


Pro Glu Lys Pro Ser Ala Leu Leu Gly Asn Ser Leu Ala Leu Pro Arg 
            660                 665                 670


Arg Pro Gln Asn Arg Asp Ser Ile Leu Asn Pro Ser Asp Lys Glu Glu 
        675                 680                 685


Val Pro Thr Pro Thr Leu Gly Ser Ile Thr Ile Pro Arg Pro Gln Gly 
    690                 695                 700


Arg Lys Thr Pro Glu Leu Gly Ile Val Pro Pro Pro Pro Ile Pro Arg 
705                 710                 715                 720


Pro Ala Lys Leu Gln Ala Ala Gly Ala Ala Leu Gly Asp Val Ser Glu 
                725                 730                 735


Arg Leu Gln Thr Asp Arg Asp Arg Arg Ala Ala Leu Ser Pro Gly Leu 
            740                 745                 750


Leu Pro Gly Val Val Pro Gln Gly Pro Thr Glu Leu Leu Gln Pro Leu 
        755                 760                 765


Ser Pro Gly Pro Gly Ala Ala Gly Thr Ser Ser Asp Ala Leu Leu Ala 
    770                 775                 780


Leu Leu Asp Pro Leu Ser Thr Ala Trp Ser Gly Ser Thr Leu Pro Ser 
785                 790                 795                 800


Arg Pro Ala Thr Pro Asn Val Ala Thr Pro Phe Thr Pro Gln Phe Ser 
                805                 810                 815


Phe Pro Pro Ala Gly Thr Pro Thr Pro Phe Pro Gln Pro Pro Leu Asn 
            820                 825                 830


Pro Phe Val Pro Ser Met Pro Ala Ala Pro Pro Thr Leu Pro Leu Val 
        835                 840                 845


Ser Thr Pro Ala Gly Pro Phe Gly Ala Pro Pro Ala Ser Leu Gly Pro 
    850                 855                 860


Ala Phe Ala Ser Gly Leu Leu Leu Ser Ser Ala Gly Phe Cys Ala Pro 
865                 870                 875                 880


His Arg Ser Gln Pro Asn Leu Ser Ala Leu Ser Met Pro Asn Leu Phe 
                885                 890                 895


Gly Gln Met Pro Met Gly Thr His Thr Ser Pro Leu Gln Pro Leu Gly 
            900                 905                 910


Pro Pro Ala Val Ala Pro Ser Arg Ile Arg Thr Leu Pro Leu Ala Arg 
        915                 920                 925


Ser Ser Ala Arg Ala Ala Glu Thr Lys Gln Gly Leu Ala Leu Arg Pro 
    930                 935                 940


Gly Asp Pro Pro Leu Leu Pro Pro Arg Pro Pro Gln Gly Leu Glu Pro 
945                 950                 955                 960


Thr Leu Gln Pro Ser Ala Pro Gln Gln Ala Arg Asp Pro Phe Glu Asp 
                965                 970                 975


Leu Leu Gln Lys Thr Lys Gln Asp Val Ser Pro Ser Pro Ala Leu Ala 
            980                 985                 990


Pro Ala Pro Asp Ser Val Glu Gln Leu Arg Lys Gln Trp Glu Thr Phe 
        995                 1000                1005


Glu 



<210>  6348
<211>  4797
<212>  DNA
<213>  Homo sapiens

<400>  6348
tgaaactccc tagattttac tgtataatgt caatggactc attatttgta caacagctga     60

tgtatttagg acttgttgat tcacttaatt ggtaactgta ctacattcat aacttcaaca    120

actgaaaaca ataggtcagt gtctgctgtt tatgcataaa tagtcacatc ggagcaggat    180

atgtctgaat ggcagaatat gttagtctga ggaggaatct ggcatgtgaa tggctccatt    240

gcttgccata ctgagatcct gaggtgcaga ggcaattccc ggaggactac agtgaccagg    300

aagttctaca gactttgacc aagttttgtt tccccttcta tgtggacagc ctcacagtta    360

gccaagttgg ccagaacttc acattcgtgc tcactgacat tgacagcaaa cagagattcg    420

ggttctgccg cttatcttca ggagcgaaga gctgcttctg tatcttaagg aaaatcagtg    480

gaatgagctt cttgaaactc tgcacaaact tcccatccct gacccaggag tgtctgtcca    540

tctcagcgtg cattcttatt ttactgtgcc tgataccaga gaacttccca gcatacctga    600

gaatagaaat ctgacagaat attttgtggc tgtggatgtt aacaacatgt tgcatctgta    660

cgccagtatg ctgtacgaac gccggatact catcatttgc agcaaactca gcactctgac    720

tgcctgcatc cacgggtctg cggcgatgct ctaccccatg tactggcagc acgtgtacat    780

ccccgtgctg ccgccgcatc tgctggacta ctgctgtgct cccatgccct acctcatagg    840

aatccattta agtttaatgg agaaagtcag aaacatggcc ctggatgatg tcgtgatcct    900

gaatgtggac accaacaccc tggaaacccc cttcgatgac ctccagagcc tcccaaacga    960

cgtgatctct tccctgaaga acaggctgaa aaaggtctcc acaaccactg gggatggtgt   1020

ggccagagcg ttcctcaagg cccaggctgc tttcttcggt agctaccgaa acgctctgaa   1080

aatcgagccg aaaggaagtg gagcaattct gaatactgta aagaccaaag caaatccggc   1140

catgaagact gtctacaagt tcgcaaaaga tcatgcaaaa atgggaataa aagaggtgaa   1200

aaaccgcttg aagcaaaagg acattgccga gaatggctgc gcccccaccc cagaagagca   1260

gctgccaaag actgcaccgt ccccactggt ggaggccaag gaccccaagc tccgagaaga   1320

ccggcggcca atcacagtcc actttggaca ggtgcgccca cctcgtccac atgttgttaa   1380

gagaccaaag agcaacatcg cagtggaagg ccggaggacg tctgtgccga gccctgagca   1440

cctggtaaag cccttgcgac actatgcggt cttcctctcc gaagactcct ctgatgatga   1500

atgccagcgg gaagagggcc cgagctctgg cttcaccgag agctttttct tctccgctcc   1560

ctttgaatgg ccgcagccgt atcggacact cagggagtca gacagcgcgg aaggcgacga   1620

ggcagagagt ccagagcagc aagtgcggaa gtccacaggc cctgtcccag ctccccctga   1680

ccgggctgcc agcatcgacc ttctggaaga cgtcttcagc aacctggaca tggaggccgc   1740

actgcagcca ctgggccagg ccaagagctt agaggacctt cgtgccccca aagacctgag   1800

ggagcagcca gggacctttg actatcagag gctggatctg ggcgggagtg agaggagccg   1860

cggggtgaca gtggccttga agcttaccca cccgtacaac aagctctgga gcctgggcca   1920

ggacgacatg gccatcccca gcaagccccc agctgcctcc cctgagaagc cctcagccct   1980

gctcggaaac tccctggccc tgcctcgaag gccccagaac cgggacagca tcctgaaccc   2040

cagtgacaag gaggaggtgc ccacccctac tctgggcagc atcaccatcc cccggcccca   2100

aggcaggaag accccagagc tgggcatcgt gcctccaccg cccattcccc gcccggccaa   2160

gctccaggct gccggcgccg cacttggtga cgtctcagag cggctgcaga cggatcggga   2220

caggcgagct gccctgagtc cagggctcct gcctggtgtt gtcccccaag gccccactga   2280

actgctccag ccgctcagcc ctggccccgg ggctgcaggc acgagcagtg acgccctgct   2340

cgccctcctg gacccgctca gcacagcctg gtcaggcagc accctcccgt cacgccccgc   2400

caccccgaat gtagccaccc cattcacccc ccaattcagc ttcccccctg cagggacacc   2460

caccccattc ccacagccac cactcaaccc ctttgtccca tccatgccag cagccccacc   2520

caccctgccc ctggtctcca caccagccgg gcctttcggg gcccctccag cttccctggg   2580

gccggctttt gcgtccggcc tcctgctgtc cagtgctggc ttctgtgccc ctcacaggtc   2640

tcagcccaac ctctccgccc tctccatgcc caacctcttt ggccagatgc ccatgggcac   2700

ccacacgagc cccctacagc cgctgggtcc cccagcagtt gccccgtcga ggatccgaac   2760

gttgcccctg gcccgctcaa gtgccagggc tgctgagacc aagcaggggc tggccctgag   2820

gcctggagac cccccgcttc tgcctcccag gccccctcaa ggcctggagc caacactgca   2880

gccctctgct cctcaacagg ccagagaccc ctttgaggat ttgttacaga aaaccaagca   2940

agacgtgagc ccgagtccgg ccctggcccc ggccccagac tcggtggagc agctcaggaa   3000

gcagtgggag accttcgagt gagccgggcc ctgagggtgg gggatgcacc gaggcccgag   3060

ggtccgtcca ctgctgcggt tccgaggctc ccccgccact ctctctctgc ccaggttctg   3120

ctggtgggaa gggatgggac ccctctctgc tgccccctcc tcccctccac actgcccatc   3180

tctgatgtct ggccctgggg aatggcacca gttccagcct gggaatcaac ccagttcctg   3240

agtgcccatc ccaccccgcg gttgcctctc ctcggcaccc ttgattgggt tttgcactaa   3300

agaggtcagc tgggccaatg atattgctcc agaccgagtc ctacccacct tcccccggaa   3360

gtgtcccaag aggctccgaa ggcctcccct ccgagcccag ctctcctgtc tcctccacag   3420

ccaggccctg cacgcccacc tcctcggaca caggtgacag ggttaccctc cagtttgagc   3480

tcatctgcac gagacacagg tagcttgggg ttgaagttag gactcctcct gggctggagg   3540

atttacctgg tggggcactt ccagactgtt tctagcaata tacacacacg ttctttcctg   3600

tgtcttcacc ccaaaacttc agttgattct gacctgggag gatctgggga ccagggggtc   3660

ttgggctgcc ttgtgataca cagccccagc caccctgcac gggggctgcg agcaccagca   3720

actttgattt atagaaggaa aatggaaacc cccatctgag tattttggga ggagccccca   3780

gccctcatcc agctctggca cgctgatacc tccaggtact cccctcactg tcaaagctgg   3840

ggctcagcct cttgtcatct ggagctttgt gggcaaagct gagaagctgc aacccagatt   3900

tcaacccaaa aaggtcaagc tgaatgcctc agactgatgt ggaaggcagc tggccttcct   3960

gggttggaac gaggcagtgg ccctgagccc cttctccagg gccaggtaga aaggacaaac   4020

ttggtctctg cctcggggaa gcaggaggag ggctagaagc cagtccctcc ccacctgccc   4080

agagctccag gccagcacag aaattcctga ggccaacgtc accaaagtta gattgaatgt   4140

ttattatctt tctttttcct ttttacctta ttgatttgat gaatcttgaa atggattcat   4200

ttccataaac caagttaaag tatggcccga ccatttaaga aaacaaccat ctgagacacg   4260

caggaaattg tgagcatttc gacccgagct ctcatttcct atttgtgaag ggtcagacac   4320

agtctaccca ggggtgtctg ggggacaagg gggtctctgg agatgtcacc cagggagccc   4380

cctctatgtc tgagaggctg ccactgctgc acatgctcag tgaggcttgg cggccatcct   4440

ggcacatggc tcttcctggg tcaaccgtga cctgtctggc tcaggaatgg gctctggctg   4500

ctgggggagc cgtgtcactc ctgggccatg ggggcacctc ctgggcactt aggtgtttca   4560

gcatagattc cagtttcgca ccctgggcag acccccaggc cccatccggg atagggcaga   4620

ggaggtgctg gcggccccag ggaaggaggg tgtgtacccc aaggccccct ggctgtgctg   4680

aggggctggg gtgagcgctc catgttcaca tgagcactgc tgcctcttca cttgtgggac   4740

tttttgcaaa cccaaggatg aactttgtgt gcattcaata aaatcatctt ggggaag      4797


<210>  6349
<211>  791
<212>  PRT
<213>  Homo sapiens

<400>  6349

Met Leu His Leu Tyr Ala Ser Met Leu Tyr Glu Arg Arg Ile Leu Ile 
1               5                   10                  15


Ile Cys Ser Lys Leu Ser Thr Leu Thr Ala Cys Ile His Gly Ser Ala 
            20                  25                  30


Ala Met Leu Tyr Pro Met Tyr Trp Gln His Val Tyr Ile Pro Val Leu 
        35                  40                  45


Pro Pro His Leu Leu Asp Tyr Cys Cys Ala Pro Met Pro Tyr Leu Ile 
    50                  55                  60


Gly Ile His Leu Ser Leu Met Glu Lys Val Arg Asn Met Ala Leu Asp 
65                  70                  75                  80


Asp Val Val Ile Leu Asn Val Asp Thr Asn Thr Leu Glu Thr Pro Phe 
                85                  90                  95


Asp Asp Leu Gln Ser Leu Pro Asn Asp Val Ile Ser Ser Leu Lys Asn 
            100                 105                 110


Arg Leu Lys Lys Val Ser Thr Thr Thr Gly Asp Gly Val Ala Arg Ala 
        115                 120                 125


Phe Leu Lys Ala Gln Ala Ala Phe Phe Gly Ser Tyr Arg Asn Ala Leu 
    130                 135                 140


Lys Ile Glu Pro Lys Gly Ser Gly Ala Ile Leu Asn Thr Val Lys Thr 
145                 150                 155                 160


Lys Ala Asn Pro Ala Met Lys Thr Val Tyr Lys Phe Ala Lys Asp His 
                165                 170                 175


Ala Lys Met Gly Ile Lys Glu Val Lys Asn Arg Leu Lys Gln Lys Asp 
            180                 185                 190


Ile Ala Glu Asn Gly Cys Ala Pro Thr Pro Glu Glu Gln Leu Pro Lys 
        195                 200                 205


Thr Ala Pro Ser Pro Leu Val Glu Ala Lys Asp Pro Lys Leu Arg Glu 
    210                 215                 220


Asp Arg Arg Pro Ile Thr Val His Phe Gly Gln Val Arg Pro Pro Arg 
225                 230                 235                 240


Pro His Val Val Lys Arg Pro Lys Ser Asn Ile Ala Val Glu Gly Arg 
                245                 250                 255


Arg Thr Ser Val Pro Ser Pro Glu His Leu Val Lys Pro Leu Arg His 
            260                 265                 270


Tyr Ala Val Phe Leu Ser Glu Asp Ser Ser Asp Asp Glu Cys Gln Arg 
        275                 280                 285


Glu Glu Gly Pro Ser Ser Gly Phe Thr Glu Ser Phe Phe Phe Ser Ala 
    290                 295                 300


Pro Phe Glu Trp Pro Gln Pro Tyr Arg Thr Leu Arg Glu Ser Asp Ser 
305                 310                 315                 320


Ala Glu Gly Asp Glu Ala Glu Ser Pro Glu Gln Gln Val Arg Lys Ser 
                325                 330                 335


Thr Gly Pro Val Pro Ala Pro Pro Asp Arg Ala Ala Ser Ile Asp Leu 
            340                 345                 350


Leu Glu Asp Val Phe Ser Asn Leu Asp Met Glu Ala Ala Leu Gln Pro 
        355                 360                 365


Leu Gly Gln Ala Lys Ser Leu Glu Asp Leu Arg Ala Pro Lys Asp Leu 
    370                 375                 380


Arg Glu Gln Pro Gly Thr Phe Asp Tyr Gln Arg Leu Asp Leu Gly Gly 
385                 390                 395                 400


Ser Glu Arg Ser Arg Gly Val Thr Val Ala Leu Lys Leu Thr His Pro 
                405                 410                 415


Tyr Asn Lys Leu Trp Ser Leu Gly Gln Asp Asp Met Ala Ile Pro Ser 
            420                 425                 430


Lys Pro Pro Ala Ala Ser Pro Glu Lys Pro Ser Ala Leu Leu Gly Asn 
        435                 440                 445


Ser Leu Ala Leu Pro Arg Arg Pro Gln Asn Arg Asp Ser Ile Leu Asn 
    450                 455                 460


Pro Ser Asp Lys Glu Glu Val Pro Thr Pro Thr Leu Gly Ser Ile Thr 
465                 470                 475                 480


Ile Pro Arg Pro Gln Gly Arg Lys Thr Pro Glu Leu Gly Ile Val Pro 
                485                 490                 495


Pro Pro Pro Ile Pro Arg Pro Ala Lys Leu Gln Ala Ala Gly Ala Ala 
            500                 505                 510


Leu Gly Asp Val Ser Glu Arg Leu Gln Thr Asp Arg Asp Arg Arg Ala 
        515                 520                 525


Ala Leu Ser Pro Gly Leu Leu Pro Gly Val Val Pro Gln Gly Pro Thr 
    530                 535                 540


Glu Leu Leu Gln Pro Leu Ser Pro Gly Pro Gly Ala Ala Gly Thr Ser 
545                 550                 555                 560


Ser Asp Ala Leu Leu Ala Leu Leu Asp Pro Leu Ser Thr Ala Trp Ser 
                565                 570                 575


Gly Ser Thr Leu Pro Ser Arg Pro Ala Thr Pro Asn Val Ala Thr Pro 
            580                 585                 590


Phe Thr Pro Gln Phe Ser Phe Pro Pro Ala Gly Thr Pro Thr Pro Phe 
        595                 600                 605


Pro Gln Pro Pro Leu Asn Pro Phe Val Pro Ser Met Pro Ala Ala Pro 
    610                 615                 620


Pro Thr Leu Pro Leu Val Ser Thr Pro Ala Gly Pro Phe Gly Ala Pro 
625                 630                 635                 640


Pro Ala Ser Leu Gly Pro Ala Phe Ala Ser Gly Leu Leu Leu Ser Ser 
                645                 650                 655


Ala Gly Phe Cys Ala Pro His Arg Ser Gln Pro Asn Leu Ser Ala Leu 
            660                 665                 670


Ser Met Pro Asn Leu Phe Gly Gln Met Pro Met Gly Thr His Thr Ser 
        675                 680                 685


Pro Leu Gln Pro Leu Gly Pro Pro Ala Val Ala Pro Ser Arg Ile Arg 
    690                 695                 700


Thr Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala Ala Glu Thr Lys Gln 
705                 710                 715                 720


Gly Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu Leu Pro Pro Arg Pro 
                725                 730                 735


Pro Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser Ala Pro Gln Gln Ala 
            740                 745                 750


Arg Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr Lys Gln Asp Val Ser 
        755                 760                 765


Pro Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser Val Glu Gln Leu Arg 
    770                 775                 780


Lys Gln Trp Glu Thr Phe Glu 
785                 790


<210>  6350
<211>  2378
<212>  DNA
<213>  Homo sapiens

<400>  6350
ttcgccgggc tggagcgagt acattaaccc ctggaggcgg cggcggcggc gagggagcga     60

gcctcgagcg ggcgggcccc agccatgcca gcagccccac ccaccctgcc cctggtctcc    120

acaccagccg ggcctttcgg ggcccctcca gcttccctgg ggccggcttt tgcgtccggc    180

ctcctgctgt ccagtgctgg cttctgtgcc cctcacaggt ctcagcccaa cctctccgcc    240

ctctccatgc ccaacctctt tggccagatg cccatgggca cccacacgag ccccctacag    300

ccgctgggtc ccccagcagt tgccccgtcg aggatccgaa cgttgcccct ggcccgctca    360

agtgccaggg ctgctgagac caagcagggg ctggccctga ggcctggaga ccccccgctt    420

ctgcctccca ggccccctca aggcctggag ccaacactgc agccctctgc tcctcaacag    480

gccagagacc cctttgagga tttgttacag aaaaccaagc aagacgtgag cccgagtccg    540

gccctggccc cggccccaga ctcggtggag cagctcagga agcagtggga gaccttcgag    600

tgagccgggc cctgagggtg ggggatgcac cgaggcccga gggtccgtcc actgctgcgg    660

ttccgaggct cccccgccac tctctctctg cccaggttct gctggtggga agggatggga    720

cccctctctg ctgccccctc ctcccctcca cactgcccat ctctgatgtc tggccctggg    780

gaatggcacc agttccagcc tgggaatcaa cccagttcct gagtgcccat cccaccccgc    840

ggttgcctct cctcggcacc cttgattggg ttttgcacta aagaggtcag ctgggccaat    900

gatattgctc cagaccgagt cctacccacc ttcccccgga agtgtcccaa gaggctccga    960

aggcctcccc tccgagccca gctctcctgt ctcctccaca gccaggccct gcacgcccac   1020

ctcctcggac acaggtgaca gggttaccct ccagtttgag ctcatctgca cgagacacag   1080

gtagcttggg gttgaagtta ggactcctcc tgggctggag gatttacctg gtggggcact   1140

tccagactgt ttctagcaat atacacacac gttctttcct gtgtcttcac cccaaaactt   1200

cagttgattc tgacctggga ggatctgggg accagggggt cttgggctgc cttgtgatac   1260

acagccccag ccaccctgca cgggggctgc gagcaccagc aactttgatt tatagaagga   1320

aaatggaaac ccccatctga gtattttggg aggagccccc agccctcatc cagctctggc   1380

acgctgatac ctccaggtac tcccctcact gtcaaagctg gggctcagcc tcttgtcatc   1440

tggagctttg tgggcaaagc tgagaagctg caacccagat ttcaacccaa aaaggtcaag   1500

ctgaatgcct cagactgatg tggaaggcag ctggccttcc tgggttggaa cgaggcagtg   1560

gccctgagcc ccttctccag ggccaggtag aaaggacaaa cttggtctct gcctcgggga   1620

agcaggagga gggctagaag ccagtccctc cccacctgcc cagagctcca ggccagcaca   1680

gaaattcctg aggccaacgt caccaaagtt agattgaatg tttattatct ttctttttcc   1740

tttttacctt attgatttga tgaatcttga aatggattca tttccataaa ccaagttaaa   1800

gtatggcccg accatttaag aaaacaacca tctgagacac gcaggaaatt gtgagcattt   1860

cgacccgagc tctcatttcc tatttgtgaa gggtcagaca cagtctaccc aggggtgtct   1920

gggggacaag ggggtctctg gagatgtcac ccagggagcc ccctctatgt ctgagaggct   1980

gccactgctg cacatgctca gtgaggcttg gcggccatcc tggcacatgg ctcttcctgg   2040

gtcaaccgtg acctgtctgg ctcaggaatg ggctctggct gctgggggag ccgtgtcact   2100

cctgggccat gggggcacct cctgggcact taggtgtttc agcatagatt ccagtttcgc   2160

accctgggca gacccccagg ccccatccgg gatagggcag aggaggtgct ggcggcccca   2220

gggaaggagg gtgtgtaccc caaggccccc tggctgtgct gaggggctgg ggtgagcgct   2280

ccatgttcac atgagcactg ctgcctcttc acttgtggga ctttttgcaa acccaaggat   2340

gaactttgtg tgcattcaat aaaatcatct tggggaag                           2378


<210>  6351
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  6351

Met Pro Ala Ala Pro Pro Thr Leu Pro Leu Val Ser Thr Pro Ala Gly 
1               5                   10                  15


Pro Phe Gly Ala Pro Pro Ala Ser Leu Gly Pro Ala Phe Ala Ser Gly 
            20                  25                  30


Leu Leu Leu Ser Ser Ala Gly Phe Cys Ala Pro His Arg Ser Gln Pro 
        35                  40                  45


Asn Leu Ser Ala Leu Ser Met Pro Asn Leu Phe Gly Gln Met Pro Met 
    50                  55                  60


Gly Thr His Thr Ser Pro Leu Gln Pro Leu Gly Pro Pro Ala Val Ala 
65                  70                  75                  80


Pro Ser Arg Ile Arg Thr Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala 
                85                  90                  95


Ala Glu Thr Lys Gln Gly Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu 
            100                 105                 110


Leu Pro Pro Arg Pro Pro Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser 
        115                 120                 125


Ala Pro Gln Gln Ala Arg Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr 
    130                 135                 140


Lys Gln Asp Val Ser Pro Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser 
145                 150                 155                 160


Val Glu Gln Leu Arg Lys Gln Trp Glu Thr Phe Glu 
                165                 170


<210>  6352
<211>  2260
<212>  DNA
<213>  Homo sapiens

<400>  6352
ttcgccgggc tggagcgagt acattaaccc ctggaggcgg cggcggcggc gagggagcga     60

gcctcgagcg ggcgggcccc agcttctgtg cccctcacag gtctcagccc aacctctccg    120

ccctctccat gcccaacctc tttggccaga tgcccatggg cacccacacg agccccctac    180

agccgctggg tcccccagca gttgccccgt cgaggatccg aacgttgccc ctggcccgct    240

caagtgccag ggctgctgag accaagcagg ggctggccct gaggcctgga gaccccccgc    300

ttctgcctcc caggccccct caaggcctgg agccaacact gcagccctct gctcctcaac    360

aggccagaga cccctttgag gatttgttac agaaaaccaa gcaagacgtg agcccgagtc    420

cggccctggc cccggcccca gactcggtgg agcagctcag gaagcagtgg gagaccttcg    480

agtgagccgg gccctgaggg tgggggatgc accgaggccc gagggtccgt ccactgctgc    540

ggttccgagg ctcccccgcc actctctctc tgcccaggtt ctgctggtgg gaagggatgg    600

gacccctctc tgctgccccc tcctcccctc cacactgccc atctctgatg tctggccctg    660

gggaatggca ccagttccag cctgggaatc aacccagttc ctgagtgccc atcccacccc    720

gcggttgcct ctcctcggca cccttgattg ggttttgcac taaagaggtc agctgggcca    780

atgatattgc tccagaccga gtcctaccca ccttcccccg gaagtgtccc aagaggctcc    840

gaaggcctcc cctccgagcc cagctctcct gtctcctcca cagccaggcc ctgcacgccc    900

acctcctcgg acacaggtga cagggttacc ctccagtttg agctcatctg cacgagacac    960

aggtagcttg gggttgaagt taggactcct cctgggctgg aggatttacc tggtggggca   1020

cttccagact gtttctagca atatacacac acgttctttc ctgtgtcttc accccaaaac   1080

ttcagttgat tctgacctgg gaggatctgg ggaccagggg gtcttgggct gccttgtgat   1140

acacagcccc agccaccctg cacgggggct gcgagcacca gcaactttga tttatagaag   1200

gaaaatggaa acccccatct gagtattttg ggaggagccc ccagccctca tccagctctg   1260

gcacgctgat acctccaggt actcccctca ctgtcaaagc tggggctcag cctcttgtca   1320

tctggagctt tgtgggcaaa gctgagaagc tgcaacccag atttcaaccc aaaaaggtca   1380

agctgaatgc ctcagactga tgtggaaggc agctggcctt cctgggttgg aacgaggcag   1440

tggccctgag ccccttctcc agggccaggt agaaaggaca aacttggtct ctgcctcggg   1500

gaagcaggag gagggctaga agccagtccc tccccacctg cccagagctc caggccagca   1560

cagaaattcc tgaggccaac gtcaccaaag ttagattgaa tgtttattat ctttcttttt   1620

cctttttacc ttattgattt gatgaatctt gaaatggatt catttccata aaccaagtta   1680

aagtatggcc cgaccattta agaaaacaac catctgagac acgcaggaaa ttgtgagcat   1740

ttcgacccga gctctcattt cctatttgtg aagggtcaga cacagtctac ccaggggtgt   1800

ctgggggaca agggggtctc tggagatgtc acccagggag ccccctctat gtctgagagg   1860

ctgccactgc tgcacatgct cagtgaggct tggcggccat cctggcacat ggctcttcct   1920

gggtcaaccg tgacctgtct ggctcaggaa tgggctctgg ctgctggggg agccgtgtca   1980

ctcctgggcc atgggggcac ctcctgggca cttaggtgtt tcagcataga ttccagtttc   2040

gcaccctggg cagaccccca ggccccatcc gggatagggc agaggaggtg ctggcggccc   2100

cagggaagga gggtgtgtac cccaaggccc cctggctgtg ctgaggggct ggggtgagcg   2160

ctccatgttc acatgagcac tgctgcctct tcacttgtgg gactttttgc aaacccaagg   2220

atgaactttg tgtgcattca ataaaatcat cttggggaag                         2260


<210>  6353
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  6353

Met Pro Asn Leu Phe Gly Gln Met Pro Met Gly Thr His Thr Ser Pro 
1               5                   10                  15


Leu Gln Pro Leu Gly Pro Pro Ala Val Ala Pro Ser Arg Ile Arg Thr 
            20                  25                  30


Leu Pro Leu Ala Arg Ser Ser Ala Arg Ala Ala Glu Thr Lys Gln Gly 
        35                  40                  45


Leu Ala Leu Arg Pro Gly Asp Pro Pro Leu Leu Pro Pro Arg Pro Pro 
    50                  55                  60


Gln Gly Leu Glu Pro Thr Leu Gln Pro Ser Ala Pro Gln Gln Ala Arg 
65                  70                  75                  80


Asp Pro Phe Glu Asp Leu Leu Gln Lys Thr Lys Gln Asp Val Ser Pro 
                85                  90                  95


Ser Pro Ala Leu Ala Pro Ala Pro Asp Ser Val Glu Gln Leu Arg Lys 
            100                 105                 110


Gln Trp Glu Thr Phe Glu 
        115


<210>  6354
<211>  2137
<212>  DNA
<213>  Homo sapiens

<400>  6354
cgcgcgccgg gcacgcgcgc cggcgaccat ggcgttcgcc gggctggagc gagtacatta     60

acccctggag gcggcggcgg cggcgaggga gcgagcctcg agcgggcggg ccccagcctg    120

agggaaggga ggaaggggcg gggagagcgc cagagggagg ccggtcggcc gcgggcgggc    180

gggcagcgca gcgccgagcg gggcccgcgg gcccatgagg aggcctgggg accatgggct    240

ccaggatcaa gcagaatcca gagaccacat ttgaagtata tgttgaagtg gcctatccca    300

ggacaggtgg cactctttca gatcctgagg tgcagaggca attcccggag gactacagtg    360

accaggaagt tctacagact ttgaccaagt tttgtttccc cttctatgtg gacagcctca    420

cagttagcca agttggccag aacttcacat tcgtgctcac tgacattgac agcaaacaga    480

gattcgggtt ctgccgctta tcttcaggag cgaagagctg cttctgtatc ttaagctatc    540

tcccctggtt cgaggtattt tataagctgc ttaacatcct ggcagattac acgacaaaaa    600

gacaggaaaa tcagtggaat gagcttcttg aaactctgca caaacttccc atccctgacc    660

caggagtgtc tgtccatctc agcgtgcatt cttattttac tgtgcctgat accagagaac    720

ttcccagcat acctgagaat agaaatctga cagaatattt tgtggctgtg gatgttaaca    780

acatgttgca tctgtacgcc agtatgctgt acgaacgccg gatactcatc atttgcagca    840

aactcagcac tctgactgcc tgcatccacg ggtctgcggc gatgctctac cccatgtact    900

ggcagcacgt gtacatcccc gtgctgccgc cgcatctgct ggactactgc tgtgctccca    960

tgccctacct cataggaatc catttaagtt taatggagaa agtcagaaac atggccctgg   1020

atgatgtcgt gatcctgaat gtggacacca acaccctgga aacccccttc gatgacctcc   1080

agagcctccc aaacgacgtg atctcttccc tgaagaacag gctgaaaaag gtctccacaa   1140

ccactgggga tggtgtggcc agagcgttcc tcaaggccca ggctgctttc ttcggtagct   1200

accgaaacgc tctgaaaatc gagccggagg agccgatcac tttctgtgag gaagccttcg   1260

tgtcccacta ccgctccgga gccatgaggc agttcctgca gaacgccaca cagctgcagc   1320

tcttcaagca gtttattgat ggtcgattag atcttctcaa ttccggcgaa ggtttcagtg   1380

atgtttttga agaggaaatc aacatgggcg agtacgctgg cagtgacaaa ctgtaccatc   1440

agtggctctc cactgtccgg aaaggaagtg gagcaattct gaatactgta aagaccaaag   1500

caaatccggc catgaagact gtctacaagt tcgcaaaaga tcatgcaaaa atgggaataa   1560

aagaggtgaa aaaccgcttg aagcaaaagg acattgccga gaatggctgc gcccccaccc   1620

cagaagagca gctgccaaag actgcaccgt ccccactggt ggaggccaag gaccccaagc   1680

tccgagaaga ccggcggcca atcacagtcc actttggaca ggtgcgccca cctcgtccac   1740

atgttgttaa gagaccaaag agcaacatcg cagtggaagg ccggaggacg tctgtgccga   1800

gccctgagca aaacaccatt gcaacaccag ctacactcca catcctacag aaaagcatta   1860

cccattttgc ggccaagttc ccgacgagag gctggacctc ttcatcacat tgacttacgc   1920

cgttgctttt ccagactggg cagaggggct gacttcgcag tgtgtgccaa agagccggtg   1980

tctgataatc ccattttcct gcttatcacc tgaactgtgt cagtatcact tttagttttg   2040

ttggttggtt ggtttgttgt ttgtttaata tgccctgttt tctacttctg ttggaaaata   2100

tttggggttg aaataaacca gtgggagcat gggagcc                            2137


<210>  6355
<211>  559
<212>  PRT
<213>  Homo sapiens

<400>  6355

Met Gly Ser Arg Ile Lys Gln Asn Pro Glu Thr Thr Phe Glu Val Tyr 
1               5                   10                  15


Val Glu Val Ala Tyr Pro Arg Thr Gly Gly Thr Leu Ser Asp Pro Glu 
            20                  25                  30


Val Gln Arg Gln Phe Pro Glu Asp Tyr Ser Asp Gln Glu Val Leu Gln 
        35                  40                  45


Thr Leu Thr Lys Phe Cys Phe Pro Phe Tyr Val Asp Ser Leu Thr Val 
    50                  55                  60


Ser Gln Val Gly Gln Asn Phe Thr Phe Val Leu Thr Asp Ile Asp Ser 
65                  70                  75                  80


Lys Gln Arg Phe Gly Phe Cys Arg Leu Ser Ser Gly Ala Lys Ser Cys 
                85                  90                  95


Phe Cys Ile Leu Ser Tyr Leu Pro Trp Phe Glu Val Phe Tyr Lys Leu 
            100                 105                 110


Leu Asn Ile Leu Ala Asp Tyr Thr Thr Lys Arg Gln Glu Asn Gln Trp 
        115                 120                 125


Asn Glu Leu Leu Glu Thr Leu His Lys Leu Pro Ile Pro Asp Pro Gly 
    130                 135                 140


Val Ser Val His Leu Ser Val His Ser Tyr Phe Thr Val Pro Asp Thr 
145                 150                 155                 160


Arg Glu Leu Pro Ser Ile Pro Glu Asn Arg Asn Leu Thr Glu Tyr Phe 
                165                 170                 175


Val Ala Val Asp Val Asn Asn Met Leu His Leu Tyr Ala Ser Met Leu 
            180                 185                 190


Tyr Glu Arg Arg Ile Leu Ile Ile Cys Ser Lys Leu Ser Thr Leu Thr 
        195                 200                 205


Ala Cys Ile His Gly Ser Ala Ala Met Leu Tyr Pro Met Tyr Trp Gln 
    210                 215                 220


His Val Tyr Ile Pro Val Leu Pro Pro His Leu Leu Asp Tyr Cys Cys 
225                 230                 235                 240


Ala Pro Met Pro Tyr Leu Ile Gly Ile His Leu Ser Leu Met Glu Lys 
                245                 250                 255


Val Arg Asn Met Ala Leu Asp Asp Val Val Ile Leu Asn Val Asp Thr 
            260                 265                 270


Asn Thr Leu Glu Thr Pro Phe Asp Asp Leu Gln Ser Leu Pro Asn Asp 
        275                 280                 285


Val Ile Ser Ser Leu Lys Asn Arg Leu Lys Lys Val Ser Thr Thr Thr 
    290                 295                 300


Gly Asp Gly Val Ala Arg Ala Phe Leu Lys Ala Gln Ala Ala Phe Phe 
305                 310                 315                 320


Gly Ser Tyr Arg Asn Ala Leu Lys Ile Glu Pro Glu Glu Pro Ile Thr 
                325                 330                 335


Phe Cys Glu Glu Ala Phe Val Ser His Tyr Arg Ser Gly Ala Met Arg 
            340                 345                 350


Gln Phe Leu Gln Asn Ala Thr Gln Leu Gln Leu Phe Lys Gln Phe Ile 
        355                 360                 365


Asp Gly Arg Leu Asp Leu Leu Asn Ser Gly Glu Gly Phe Ser Asp Val 
    370                 375                 380


Phe Glu Glu Glu Ile Asn Met Gly Glu Tyr Ala Gly Ser Asp Lys Leu 
385                 390                 395                 400


Tyr His Gln Trp Leu Ser Thr Val Arg Lys Gly Ser Gly Ala Ile Leu 
                405                 410                 415


Asn Thr Val Lys Thr Lys Ala Asn Pro Ala Met Lys Thr Val Tyr Lys 
            420                 425                 430


Phe Ala Lys Asp His Ala Lys Met Gly Ile Lys Glu Val Lys Asn Arg 
        435                 440                 445


Leu Lys Gln Lys Asp Ile Ala Glu Asn Gly Cys Ala Pro Thr Pro Glu 
    450                 455                 460


Glu Gln Leu Pro Lys Thr Ala Pro Ser Pro Leu Val Glu Ala Lys Asp 
465                 470                 475                 480


Pro Lys Leu Arg Glu Asp Arg Arg Pro Ile Thr Val His Phe Gly Gln 
                485                 490                 495


Val Arg Pro Pro Arg Pro His Val Val Lys Arg Pro Lys Ser Asn Ile 
            500                 505                 510


Ala Val Glu Gly Arg Arg Thr Ser Val Pro Ser Pro Glu Gln Asn Thr 
        515                 520                 525


Ile Ala Thr Pro Ala Thr Leu His Ile Leu Gln Lys Ser Ile Thr His 
    530                 535                 540


Phe Ala Ala Lys Phe Pro Thr Arg Gly Trp Thr Ser Ser Ser His 
545                 550                 555


<210>  6356
<211>  2095
<212>  DNA
<213>  Homo sapiens

<400>  6356
ggcgcgcgcc gggcacgcgc gccggcgacc atggcgttcg ccgggctgga gcgagtacat     60

taacccctgg aggcggcggc ggcggcgagg gagcgagcct cgagcgggcg ggccccagcc    120

tgagggaagg gaggaagggg cggggagagc gccagaggga ggccggtcgg ccgcgggcgg    180

gcgggcagcg cagcgccgag cggggcccgc gggcccatga ggaggcctgg ggaccatggg    240

ctccaggatc aagcagaatc cagagaccac atttgaagta tatgttgaag tggcctatcc    300

caggacaggt ggcactcttt caggaagttc tacagacttt gaccaagttt tgtttcccct    360

tctatgtgga cagcctcaca gttagccaag ttggccagaa cttcacattc gtgctcactg    420

acattgacag caaacagaga ttcgggttct gccgcttatc ttcaggagcg aagagctgct    480

tctgtatctt aagctatctc ccctggttcg aggtatttta taagctgctt aacatcctgg    540

cagattacac gacaaaaaga caggaaaatc agtggaatga gcttcttgaa actctgcaca    600

aacttcccat ccctgaccca ggagtgtctg tccatctcag cgtgcattct tattttactg    660

tgcctgatac cagagaactt cccagcatac ctgagaatag aaatctgaca gaatattttg    720

tggctgtgga tgttaacaac atgttgcatc tgtacgccag tatgctgtac gaacgccgga    780

tactcatcat ttgcagcaaa ctcagcactc tgactgcctg catccacggg tctgcggcga    840

tgctctaccc catgtactgg cagcacgtgt acatccccgt gctgccgccg catctgctgg    900

actactgctg tgctcccatg ccctacctca taggaatcca tttaagttta atggagaaag    960

tcagaaacat ggccctggat gatgtcgtga tcctgaatgt ggacaccaac accctggaaa   1020

cccccttcga tgacctccag agcctcccaa acgacgtgat ctcttccctg aagaacaggc   1080

tgaaaaaggt ctccacaacc actggggatg gtgtggccag agcgttcctc aaggcccagg   1140

ctgctttctt cggtagctac cgaaacgctc tgaaaatcga gccggaggag ccgatcactt   1200

tctgtgagga agccttcgtg tcccactacc gctccggagc catgaggcag ttcctgcaga   1260

acgccacaca gctgcagctc ttcaagcagt ttattgatgg tcgattagat cttctcaatt   1320

ccggcgaagg tttcagtgat gtttttgaag aggaaatcaa catgggcgag tacgctggca   1380

gtgacaaact gtaccatcag tggctctcca ctgtccggaa aggaagtgga gcaattctga   1440

atactgtaaa gaccaaagca aatccggcca tgaagactgt ctacaagttc gcaaaagatc   1500

atgcaaaaat gggaataaaa gaggtgaaaa accgcttgaa gcaaaaggac attgccgaga   1560

atggctgcgc ccccacccca gaagagcagc tgccaaagac tgcaccgtcc ccactggtgg   1620

aggccaagga ccccaagctc cgagaagacc ggcggccaat cacagtccac tttggacagg   1680

tgcgcccacc tcgtccacat gttgttaaga gaccaaagag caacatcgca gtggaaggcc   1740

ggaggacgtc tgtgccgagc cctgagcaaa acaccattgc aacaccagct acactccaca   1800

tcctacagaa aagcattacc cattttgcgg ccaagttccc gacgagaggc tggacctctt   1860

catcacattg acttacgccg ttgcttttcc agactgggca gaggggctga cttcgcagtg   1920

tgtgccaaag agccggtgtc tgataatccc attttcctgc ttatcacctg aactgtgtca   1980

gtatcacttt tagttttgtt ggttggttgg tttgttgttt gtttaatatg ccctgttttc   2040

tacttctgtt ggaaaatatt tggggttgaa ataaaccagt gggagcatgg gagcc        2095


<210>  6357
<211>  529
<212>  PRT
<213>  Homo sapiens

<400>  6357

Met Leu Lys Trp Pro Ile Pro Gly Gln Val Ala Leu Phe Gln Glu Val 
1               5                   10                  15


Leu Gln Thr Leu Thr Lys Phe Cys Phe Pro Phe Tyr Val Asp Ser Leu 
            20                  25                  30


Thr Val Ser Gln Val Gly Gln Asn Phe Thr Phe Val Leu Thr Asp Ile 
        35                  40                  45


Asp Ser Lys Gln Arg Phe Gly Phe Cys Arg Leu Ser Ser Gly Ala Lys 
    50                  55                  60


Ser Cys Phe Cys Ile Leu Ser Tyr Leu Pro Trp Phe Glu Val Phe Tyr 
65                  70                  75                  80


Lys Leu Leu Asn Ile Leu Ala Asp Tyr Thr Thr Lys Arg Gln Glu Asn 
                85                  90                  95


Gln Trp Asn Glu Leu Leu Glu Thr Leu His Lys Leu Pro Ile Pro Asp 
            100                 105                 110


Pro Gly Val Ser Val His Leu Ser Val His Ser Tyr Phe Thr Val Pro 
        115                 120                 125


Asp Thr Arg Glu Leu Pro Ser Ile Pro Glu Asn Arg Asn Leu Thr Glu 
    130                 135                 140


Tyr Phe Val Ala Val Asp Val Asn Asn Met Leu His Leu Tyr Ala Ser 
145                 150                 155                 160


Met Leu Tyr Glu Arg Arg Ile Leu Ile Ile Cys Ser Lys Leu Ser Thr 
                165                 170                 175


Leu Thr Ala Cys Ile His Gly Ser Ala Ala Met Leu Tyr Pro Met Tyr 
            180                 185                 190


Trp Gln His Val Tyr Ile Pro Val Leu Pro Pro His Leu Leu Asp Tyr 
        195                 200                 205


Cys Cys Ala Pro Met Pro Tyr Leu Ile Gly Ile His Leu Ser Leu Met 
    210                 215                 220


Glu Lys Val Arg Asn Met Ala Leu Asp Asp Val Val Ile Leu Asn Val 
225                 230                 235                 240


Asp Thr Asn Thr Leu Glu Thr Pro Phe Asp Asp Leu Gln Ser Leu Pro 
                245                 250                 255


Asn Asp Val Ile Ser Ser Leu Lys Asn Arg Leu Lys Lys Val Ser Thr 
            260                 265                 270


Thr Thr Gly Asp Gly Val Ala Arg Ala Phe Leu Lys Ala Gln Ala Ala 
        275                 280                 285


Phe Phe Gly Ser Tyr Arg Asn Ala Leu Lys Ile Glu Pro Glu Glu Pro 
    290                 295                 300


Ile Thr Phe Cys Glu Glu Ala Phe Val Ser His Tyr Arg Ser Gly Ala 
305                 310                 315                 320


Met Arg Gln Phe Leu Gln Asn Ala Thr Gln Leu Gln Leu Phe Lys Gln 
                325                 330                 335


Phe Ile Asp Gly Arg Leu Asp Leu Leu Asn Ser Gly Glu Gly Phe Ser 
            340                 345                 350


Asp Val Phe Glu Glu Glu Ile Asn Met Gly Glu Tyr Ala Gly Ser Asp 
        355                 360                 365


Lys Leu Tyr His Gln Trp Leu Ser Thr Val Arg Lys Gly Ser Gly Ala 
    370                 375                 380


Ile Leu Asn Thr Val Lys Thr Lys Ala Asn Pro Ala Met Lys Thr Val 
385                 390                 395                 400


Tyr Lys Phe Ala Lys Asp His Ala Lys Met Gly Ile Lys Glu Val Lys 
                405                 410                 415


Asn Arg Leu Lys Gln Lys Asp Ile Ala Glu Asn Gly Cys Ala Pro Thr 
            420                 425                 430


Pro Glu Glu Gln Leu Pro Lys Thr Ala Pro Ser Pro Leu Val Glu Ala 
        435                 440                 445


Lys Asp Pro Lys Leu Arg Glu Asp Arg Arg Pro Ile Thr Val His Phe 
    450                 455                 460


Gly Gln Val Arg Pro Pro Arg Pro His Val Val Lys Arg Pro Lys Ser 
465                 470                 475                 480


Asn Ile Ala Val Glu Gly Arg Arg Thr Ser Val Pro Ser Pro Glu Gln 
                485                 490                 495


Asn Thr Ile Ala Thr Pro Ala Thr Leu His Ile Leu Gln Lys Ser Ile 
            500                 505                 510


Thr His Phe Ala Ala Lys Phe Pro Thr Arg Gly Trp Thr Ser Ser Ser 
        515                 520                 525


His 



<210>  6358
<211>  2828
<212>  DNA
<213>  Homo sapiens

<400>  6358
ccggtcggcc gcgggcgggc gggcagcgca gcgccgagcg gggcccgcgg gcccatgagg     60

aggcctgggg accatgggct ccaggatcaa gcagaatcca gagaccacat ttgaagtata    120

tgttgaagtg gcctatccca ggacaggtgg cactctttca gatcctgagg tgcagaggca    180

attcccggag gactacagtg accagcctca cagttagcca agttggccag aacttcacat    240

tcgtgctcac tgacattgac agcaaacaga gattcgggtt ctgccgctta tcttcaggag    300

cgaagagctg cttctgtatc ttaagctatc tcccctggtt cgaggtattt tataagctgc    360

ttaacatcct ggcagattac acgacaaaaa gacaggaaaa tcagtggaat gagcttcttg    420

aaactctgca caaacttccc atccctgacc caggagtgtc tgtccatctc agcgtgcatt    480

cttattttac tgtgcctgat accagagaac ttcccagcat acctgagaat agaaatctga    540

cagaatattt tgtggctgtg gatgttaaca acatgttgca tctgtacgcc agtatgctgt    600

acgaacgccg gatactcatc atttgcagca aactcagcac tctgactgcc tgcatccacg    660

ggtctgcggc gatgctctac cccatgtact ggcagcacgt gtacatcccc gtgctgccgc    720

cgcatctgct ggactactgc tgtgctccca tgccctacct cataggaatc catttaagtt    780

taatggagaa agtcagaaac atggccctgg atgatgtcgt gatcctgaat gtggacacca    840

acaccctgga aacccccttc gatgacctcc agagcctccc aaacgacgtg atctcttccc    900

tgaagaacag gctgaaaaag gtctccacaa ccactgggga tggtgtggcc agagcgttcc    960

tcaaggccca ggctgctttc ttcggtagct accgaaacgc tctgaaaatc gagccggagg   1020

agccgatcac tttctgtgag gaagccttcg tgtcccacta ccgctccgga gccatgaggc   1080

agttcctgca gaacgccaca cagctgcagc tcttcaagca gtttattgat ggtcgattag   1140

atcttctcaa ttccggcgaa ggtttcagtg atgtttttga agaggaaatc aacatgggcg   1200

agtacgctgg cagtgacaaa ctgtaccatc agtggctctc cactgtccgg aaaggaagtg   1260

gagcaattct gaatactgta aagaccaaag caaatccggc catgaagact gtctacaagt   1320

tcgcaaaaga tcatgcaaaa atgggaataa aagaggtgaa aaaccgcttg aagcaaaagg   1380

acattgccga gaatggctgc gcccccaccc cagaagagca gctgccaaag actgcaccgt   1440

ccccactggt ggaggccaag gaccccaagc tccgagaaga ccggcggcca atcacagtcc   1500

actttggaca ggcgttgtga atccccaaaa ggagcaagac agaagacagc atttctcaga   1560

tttgcctggc tggggaacct ccttttttcc cttcacacaa tgcgtctccc aggatggtgt   1620

ttctcagcag acaccctgtg agatgccggc cttccactga gatgatttca tctgccaagt   1680

gccaagactg ggtggacatt tttttaagtc ctctctggaa acaaatgtag gcgatggact   1740

gggaggggga gaggctggag gcagggaaac ctgctgatgg taatggttgc taatgtctgt   1800

tggtggcact gtgcaaagaa cctgacgtcc atcatctcgt tgaatcttcc taacaggaca   1860

ctcgggtagg cagtgctgtt acctgtactt cacagatgag gacagtaagg cttggaatgg   1920

tcaaatcgtg ggcctggagt aacccaggga gtaaatggga gaactggggt tctctccaaa   1980

actgtctgac ccctagaggc tgcctcccga gcgctctggt gcactgccac ccagcaggaa   2040

tggaaatagc ccaagccaga ggtgacaagc agtgaagaca gtggggctgg agaagatggt   2100

tcccccgaag tagaaaggcc aagcataaga gaagcagtat tgtggggagt ggtgtaggag   2160

agctgggtgt ctagacaggg tagcagcctg tgcaccggtg gagggggtgg gctcccctct   2220

ccctgatcac ctcttcctct tgatgaatgg tgtgaattga ggggtggggg ggctgttccc   2280

ctttccccca cacacttcct gtaagccagg aaggggaaaa aacatggtgg ccttgcccat   2340

ccctaggcag cacccccaac tcccgggtag ctgtcagctg aagggtcacc aagcatgggt   2400

cagccctcac gcccagctaa tggcatagga tctgggaagc cacggtgtca ttctatccca   2460

tcgtgttctc catgtgccgc cagggaaccc tccaccaagt ccctggaccc gctttcccct   2520

caggctgccc cgacaggttc catgcagagc accagggacc cagggacaac tgggacacag   2580

gccctgccct ccaggagtag tggggcaggt tcagaaaaca aattctaagg cagatttgag   2640

atctgaagtg tcactcccac tcagtagagc cctatatcag cactgtccaa gaaaaacata   2700

atgggagctt catacgggag tcacatgtgg aattctgaat gtgaaacata aacaggtgaa   2760

attgatttta atataatgaa cccaatatat ccaaaatatt atttcaacat gtaatcaatc   2820

taaaaatt                                                            2828


<210>  6359
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  6359

Met Leu Lys Trp Pro Ile Pro Gly Gln Val Ala Leu Phe Gln Ile Leu 
1               5                   10                  15


Arg Cys Arg Gly Asn Ser Arg Arg Thr Thr Val Thr Ser Leu Thr Val 
            20                  25                  30


Ser Gln Val Gly Gln Asn Phe Thr Phe Val Leu Thr Asp Ile Asp Ser 
        35                  40                  45


Lys Gln Arg Phe Gly Phe Cys Arg Leu Ser Ser Gly Ala Lys Ser Cys 
    50                  55                  60


Phe Cys Ile Leu Ser Tyr Leu Pro Trp Phe Glu Val Phe Tyr Lys Leu 
65                  70                  75                  80


Leu Asn Ile Leu Ala Asp Tyr Thr Thr Lys Arg Gln Glu Asn Gln Trp 
                85                  90                  95


Asn Glu Leu Leu Glu Thr Leu His Lys Leu Pro Ile Pro Asp Pro Gly 
            100                 105                 110


Val Ser Val His Leu Ser Val His Ser Tyr Phe Thr Val Pro Asp Thr 
        115                 120                 125


Arg Glu Leu Pro Ser Ile Pro Glu Asn Arg Asn Leu Thr Glu Tyr Phe 
    130                 135                 140


Val Ala Val Asp Val Asn Asn Met Leu His Leu Tyr Ala Ser Met Leu 
145                 150                 155                 160


Tyr Glu Arg Arg Ile Leu Ile Ile Cys Ser Lys Leu Ser Thr Leu Thr 
                165                 170                 175


Ala Cys Ile His Gly Ser Ala Ala Met Leu Tyr Pro Met Tyr Trp Gln 
            180                 185                 190


His Val Tyr Ile Pro Val Leu Pro Pro His Leu Leu Asp Tyr Cys Cys 
        195                 200                 205


Ala Pro Met Pro Tyr Leu Ile Gly Ile His Leu Ser Leu Met Glu Lys 
    210                 215                 220


Val Arg Asn Met Ala Leu Asp Asp Val Val Ile Leu Asn Val Asp Thr 
225                 230                 235                 240


Asn Thr Leu Glu Thr Pro Phe Asp Asp Leu Gln Ser Leu Pro Asn Asp 
                245                 250                 255


Val Ile Ser Ser Leu Lys Asn Arg Leu Lys Lys Val Ser Thr Thr Thr 
            260                 265                 270


Gly Asp Gly Val Ala Arg Ala Phe Leu Lys Ala Gln Ala Ala Phe Phe 
        275                 280                 285


Gly Ser Tyr Arg Asn Ala Leu Lys Ile Glu Pro Glu Glu Pro Ile Thr 
    290                 295                 300


Phe Cys Glu Glu Ala Phe Val Ser His Tyr Arg Ser Gly Ala Met Arg 
305                 310                 315                 320


Gln Phe Leu Gln Asn Ala Thr Gln Leu Gln Leu Phe Lys Gln Phe Ile 
                325                 330                 335


Asp Gly Arg Leu Asp Leu Leu Asn Ser Gly Glu Gly Phe Ser Asp Val 
            340                 345                 350


Phe Glu Glu Glu Ile Asn Met Gly Glu Tyr Ala Gly Ser Asp Lys Leu 
        355                 360                 365


Tyr His Gln Trp Leu Ser Thr Val Arg Lys Gly Ser Gly Ala Ile Leu 
    370                 375                 380


Asn Thr Val Lys Thr Lys Ala Asn Pro Ala Met Lys Thr Val Tyr Lys 
385                 390                 395                 400


Phe Ala Lys Asp His Ala Lys Met Gly Ile Lys Glu Val Lys Asn Arg 
                405                 410                 415


Leu Lys Gln Lys Asp Ile Ala Glu Asn Gly Cys Ala Pro Thr Pro Glu 
            420                 425                 430


Glu Gln Leu Pro Lys Thr Ala Pro Ser Pro Leu Val Glu Ala Lys Asp 
        435                 440                 445


Pro Lys Leu Arg Glu Asp Arg Arg Pro Ile Thr Val His Phe Gly Gln 
    450                 455                 460


Ala Leu 
465


<210>  6360
<211>  555
<212>  DNA
<213>  Homo sapiens

<400>  6360
actattctgt tttgcttgga ttcactccct atctgctatt acgacgatcc taatattcag     60

aagtctccta ggatctttat cgctctcctt gtttctgaga gtcaaatcgg ggtttatggc    120

ctgcaaggat gagattcagc ctcaggtaac atttacagag tgaatagtgc gcccagtgct    180

gggctctgtg ctttcatatc tggatggtca ccggatcttt ttaaccacct tgaggtaggt    240

gtgaatacta tccccatttt cacagaagag gacagaggga ctccaagagg tcaagtaact    300

tgcccaagac tggctgttct gtaaaatggg aataatatct atcttctagg aatgctgatg    360

gaattgtatt atctctatta agatctttga cctacttgct ctccatagag ttccaaaaag    420

cagtatgaat taagctcaga tatgaaaata tggaagaaaa atggggcctt tgtgctacag    480

ggaatcacac tgaagtattt acattagaga acaagattta gttaagcctt ccctatttat    540

catttataaa ggaaa                                                     555


<210>  6361
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  6361

Asp Ser Ala Ser Gly Asn Ile Tyr Arg Val Asn Ser Ala Pro Ser Ala 
1               5                   10                  15


Gly Leu Cys Ala Phe Ile Ser Gly Trp Ser Pro Asp Leu Phe Asn His 
            20                  25                  30


Leu Glu Val Gly Val Asn Thr Ile Pro Ile Phe Thr Glu Glu Asp Arg 
        35                  40                  45


Gly Thr Pro Arg Gly Gln Val Thr Cys Pro Arg Leu Ala Val Leu 
    50                  55                  60


<210>  6362
<211>  3368
<212>  DNA
<213>  Homo sapiens

<400>  6362
gagtccagca gtgtcctctg cagaagggga agtgaaaaca tttgttcaca tggatagtgg     60

acctatgtga ggttctggct gtccatgata aagcactggt taagtagaca tggggcacca    120

aaaataatat cttttatagc ccccaaacag cgtttgtctt ttgtcttttt ccagggcgca    180

accatgtcgc catttcttcg gattggcttg tccaactttg actgcgggtc ctgccagtct    240

tgtcagggcg aggctgttaa cccttactgt gctgtgctcg tcaaagagta tgtcgaatca    300

gagaacgggc agatgtatat ccagaaaaag cctaccatgt acccaccctg ggacagcact    360

tttgatgccc atatcaacaa gggaagagtc atgcagatca ttgtgaaagg caaaaacgtg    420

gacctcatct ctgaaaccac cgtggagctc tactcgctgg ctgagaggtg caggaagaac    480

aacgggaaga cagaaatatg gttagagctg aaacctcaag gccgaatgct aatgaatgca    540

agatactttc tggaaatgag tgacacaaag gacatgaatg aatttgagac ggaaggcttc    600

tttgctttgc atcagcgccg gggtgccatc aagcaggcaa aggtccacca cgtcaagtgc    660

cacgagttca ctgccacctt cttcccacag cccacatttt gctctgtctg ccacgagttt    720

gtctggggcc tgaacaaaca gggctaccag tgccgacaat gcaatgcagc aattcacaag    780

aagtgtattg ataaagttat agcaaagtgc acaggatcag ctatcaatag ccgagaaacc    840

atgttccaca aggagagatt caaaattgac atgccacaca gatttaaagt ctacaattac    900

aagagcccga ccttctgtga acactgtggg accctgctgt ggggactggc acggcaagga    960

ctcaagtgtg atgcatgtgg catgaatgtg catcatagat gccagacaaa ggtggccaac   1020

ctttgtggca taaaccagaa gctaatggct gaagcgctgg ccatgattga gagcactcaa   1080

caggctcgct gcttaagaga tactgaacag atcttcagag aaggtccggt tgaaattggt   1140

ctcccatgct ccatcaaaaa tgaagcaagg ccgccatgtt taccgacacc gggaaaaaga   1200

gagcctcagg gcatttcctg ggagtctccg ttggatgagg tggataaaat gtgccatctt   1260

ccagaacctg aactgaacaa agaaagacca tctctgcaga ttaaactaaa aattgaggat   1320

tttatcttgc acaaaatgtt ggggaaagga agttttggca aggtcttcct ggcagaattc   1380

aagaaaacca atcaattttt cgcaataaag gccttaaaga aagatgtggt cttgatggac   1440

gatgatgttg agtgcacgat ggtagagaag agagttcttt ccttggcctg ggagcatccg   1500

tttctgacgc acatgttttg tacattccag accaaggaaa acctcttttt tgtgatggag   1560

tacctcaacg gaggggactt aatgtaccac atccaaagct gccacaagtt cgacctttcc   1620

agagcgacgt tttatgctgc tgaaatcatt cttggtctgc agttccttca ttccaaagga   1680

atagtctaca gggacctgaa gctagataac atcctgttag acaaagatgg acatatcaag   1740

atcgcggatt ttggaatgtg caaggagaac atgttaggag atgccaagac gaataccttc   1800

tgtgggacac ctgactacat cgccccagag atcttgctgg gtcagaaata caaccactct   1860

gtggactggt ggtccttcgg ggttctcctt tatgaaatgc tgattggtca gtcgcctttc   1920

cacgggcagg atgaggagga gctcttccac tccatccgca tggacaatcc cttttaccca   1980

cggtggctgg agaaggaagc aaaggacctt ctggtgaagc tcttcgtgcg agaacctgag   2040

aagaggctgg gcgtgagggg agacatccgc cagcaccctt tgtttcggga gatcaactgg   2100

gaggaacttg aacggaagga gattgaccca ccgttccggc cgaaagtgaa atcaccattt   2160

gactgcagca atttcgacaa agaattctta aacgagaagc cccggctgtc atttgccgac   2220

agagcactga tcaacagcat ggaccagaat atgttcagga acttttcctt catgaacccc   2280

gggatggagc ggctgatatc ctgaatcttg cccctccaga gacaggaaag aatttgcctt   2340

ctccctggga actggttcaa gagacactgc ttgggttcct ttttcaactt ggaaaaagaa   2400

agaaacactc aacaataaag actgagaccc gttcgccccc atgtgacttt tatctgtagc   2460

agaaaccaag tctacttcac taatgacgat gccgtgtgtc tcgtctcctg acatgtctca   2520

cagacgctcc tgaagttagg tcattactaa ccatagttat ttacttgaaa gatgggtctc   2580

cgcacttgga aaggtttcaa gacttgatac tgcaataaat tatggctctt cacctgggcg   2640

ccaactgctg atcaatgaaa tgcttgttga atcaggggca aacggagtac agacgtctca   2700

agactgaaac ggccccattg cctggtctag tagcggatct cactcagccg cagacaagta   2760

atcactaacc cgttttattc tattcctatc tgtggatgtg taaatggctg gggggccagc   2820

cctggatagg tttttatggg aattctttac aataaacata gcttgtaact tgagatctac   2880

aaatccattc atcctgattg ggcatgaaat ccatggtcaa gaggacaagt ggaaagtgag   2940

agggaaggtt tgctagacac cttcgcttgt tatcttgtca agatagaaaa gatagtatca   3000

tttcaccctt gccagtaaaa acctttccat ccacccattc tcagcagact ccagtattgg   3060

cacagtcact cactgccatt ctcacactat aacaagaaaa gaaatgaagt gcataagtct   3120

cctgggaaaa gaaccttaac cccttctcgt gccatgactg gtgatttcat gactcataag   3180

cccctccgta ggcatcattc aagatcaatg gcccatgcat gctgtttgca gcagtcaatt   3240

gagttgaatt agaattccaa ccatacattt taaaggtatt tgtgctgtgt gtatattttg   3300

ataaaatgtt gtgacttcat ggcaaacagg tggatgtgta aaaatggaat aaaaaaaaaa   3360

aaagagtc                                                            3368


<210>  6363
<211>  739
<212>  PRT
<213>  Homo sapiens

<400>  6363

Met Ile Lys His Trp Leu Ser Arg His Gly Ala Pro Lys Ile Ile Ser 
1               5                   10                  15


Phe Ile Ala Pro Lys Gln Arg Leu Ser Phe Val Phe Phe Gln Gly Ala 
            20                  25                  30


Thr Met Ser Pro Phe Leu Arg Ile Gly Leu Ser Asn Phe Asp Cys Gly 
        35                  40                  45


Ser Cys Gln Ser Cys Gln Gly Glu Ala Val Asn Pro Tyr Cys Ala Val 
    50                  55                  60


Leu Val Lys Glu Tyr Val Glu Ser Glu Asn Gly Gln Met Tyr Ile Gln 
65                  70                  75                  80


Lys Lys Pro Thr Met Tyr Pro Pro Trp Asp Ser Thr Phe Asp Ala His 
                85                  90                  95


Ile Asn Lys Gly Arg Val Met Gln Ile Ile Val Lys Gly Lys Asn Val 
            100                 105                 110


Asp Leu Ile Ser Glu Thr Thr Val Glu Leu Tyr Ser Leu Ala Glu Arg 
        115                 120                 125


Cys Arg Lys Asn Asn Gly Lys Thr Glu Ile Trp Leu Glu Leu Lys Pro 
    130                 135                 140


Gln Gly Arg Met Leu Met Asn Ala Arg Tyr Phe Leu Glu Met Ser Asp 
145                 150                 155                 160


Thr Lys Asp Met Asn Glu Phe Glu Thr Glu Gly Phe Phe Ala Leu His 
                165                 170                 175


Gln Arg Arg Gly Ala Ile Lys Gln Ala Lys Val His His Val Lys Cys 
            180                 185                 190


His Glu Phe Thr Ala Thr Phe Phe Pro Gln Pro Thr Phe Cys Ser Val 
        195                 200                 205


Cys His Glu Phe Val Trp Gly Leu Asn Lys Gln Gly Tyr Gln Cys Arg 
    210                 215                 220


Gln Cys Asn Ala Ala Ile His Lys Lys Cys Ile Asp Lys Val Ile Ala 
225                 230                 235                 240


Lys Cys Thr Gly Ser Ala Ile Asn Ser Arg Glu Thr Met Phe His Lys 
                245                 250                 255


Glu Arg Phe Lys Ile Asp Met Pro His Arg Phe Lys Val Tyr Asn Tyr 
            260                 265                 270


Lys Ser Pro Thr Phe Cys Glu His Cys Gly Thr Leu Leu Trp Gly Leu 
        275                 280                 285


Ala Arg Gln Gly Leu Lys Cys Asp Ala Cys Gly Met Asn Val His His 
    290                 295                 300


Arg Cys Gln Thr Lys Val Ala Asn Leu Cys Gly Ile Asn Gln Lys Leu 
305                 310                 315                 320


Met Ala Glu Ala Leu Ala Met Ile Glu Ser Thr Gln Gln Ala Arg Cys 
                325                 330                 335


Leu Arg Asp Thr Glu Gln Ile Phe Arg Glu Gly Pro Val Glu Ile Gly 
            340                 345                 350


Leu Pro Cys Ser Ile Lys Asn Glu Ala Arg Pro Pro Cys Leu Pro Thr 
        355                 360                 365


Pro Gly Lys Arg Glu Pro Gln Gly Ile Ser Trp Glu Ser Pro Leu Asp 
    370                 375                 380


Glu Val Asp Lys Met Cys His Leu Pro Glu Pro Glu Leu Asn Lys Glu 
385                 390                 395                 400


Arg Pro Ser Leu Gln Ile Lys Leu Lys Ile Glu Asp Phe Ile Leu His 
                405                 410                 415


Lys Met Leu Gly Lys Gly Ser Phe Gly Lys Val Phe Leu Ala Glu Phe 
            420                 425                 430


Lys Lys Thr Asn Gln Phe Phe Ala Ile Lys Ala Leu Lys Lys Asp Val 
        435                 440                 445


Val Leu Met Asp Asp Asp Val Glu Cys Thr Met Val Glu Lys Arg Val 
    450                 455                 460


Leu Ser Leu Ala Trp Glu His Pro Phe Leu Thr His Met Phe Cys Thr 
465                 470                 475                 480


Phe Gln Thr Lys Glu Asn Leu Phe Phe Val Met Glu Tyr Leu Asn Gly 
                485                 490                 495


Gly Asp Leu Met Tyr His Ile Gln Ser Cys His Lys Phe Asp Leu Ser 
            500                 505                 510


Arg Ala Thr Phe Tyr Ala Ala Glu Ile Ile Leu Gly Leu Gln Phe Leu 
        515                 520                 525


His Ser Lys Gly Ile Val Tyr Arg Asp Leu Lys Leu Asp Asn Ile Leu 
    530                 535                 540


Leu Asp Lys Asp Gly His Ile Lys Ile Ala Asp Phe Gly Met Cys Lys 
545                 550                 555                 560


Glu Asn Met Leu Gly Asp Ala Lys Thr Asn Thr Phe Cys Gly Thr Pro 
                565                 570                 575


Asp Tyr Ile Ala Pro Glu Ile Leu Leu Gly Gln Lys Tyr Asn His Ser 
            580                 585                 590


Val Asp Trp Trp Ser Phe Gly Val Leu Leu Tyr Glu Met Leu Ile Gly 
        595                 600                 605


Gln Ser Pro Phe His Gly Gln Asp Glu Glu Glu Leu Phe His Ser Ile 
    610                 615                 620


Arg Met Asp Asn Pro Phe Tyr Pro Arg Trp Leu Glu Lys Glu Ala Lys 
625                 630                 635                 640


Asp Leu Leu Val Lys Leu Phe Val Arg Glu Pro Glu Lys Arg Leu Gly 
                645                 650                 655


Val Arg Gly Asp Ile Arg Gln His Pro Leu Phe Arg Glu Ile Asn Trp 
            660                 665                 670


Glu Glu Leu Glu Arg Lys Glu Ile Asp Pro Pro Phe Arg Pro Lys Val 
        675                 680                 685


Lys Ser Pro Phe Asp Cys Ser Asn Phe Asp Lys Glu Phe Leu Asn Glu 
    690                 695                 700


Lys Pro Arg Leu Ser Phe Ala Asp Arg Ala Leu Ile Asn Ser Met Asp 
705                 710                 715                 720


Gln Asn Met Phe Arg Asn Phe Ser Phe Met Asn Pro Gly Met Glu Arg 
                725                 730                 735


Leu Ile Ser 



<210>  6364
<211>  3324
<212>  DNA
<213>  Homo sapiens

<400>  6364
agtgcgccgg gcccgccagc cccgccagcc ccgccagccc cgccagcccc gccagtcccc     60

gcgcagtccc cgcgcagtcc ccgcgcagtc ccagcgccac cgggcagcag cggcgccgtg    120

ctcgctccag ggcgcaacca tgtcgccatt tcttcggatt ggcttgtcca actttgactg    180

cgggtcctgc cagtcttgtc agggcgaggc tgttaaccct tactgtgctg tgctcgtcaa    240

agagtatgtc gaatcagaga acgggcagat gtatatccag aaaaagccta ccatgtaccc    300

accctgggac agcacttttg atgcccatat caacaaggga agagtcatgc agatcattgt    360

gaaaggcaaa aacgtggacc tcatctctga aaccaccgtg gagctctact cgctggctga    420

gaggtgcagg aagaacaacg ggaagacaga aatatggtta gagctgaaac ctcaaggccg    480

aatgctaatg aatgcaagat actttctgga aatgagtgac acaaaggaca tgaatgaatt    540

tgagacggaa ggcttctttg ctttgcatca gcgccggggt gccatcaagc aggcaaaggt    600

ccaccacgtc aagtgccacg agttcactgc caccttcttc ccacagccca cattttgctc    660

tgtctgccac gagtttgtct ggggcctgaa caaacagggc taccagtgcc gacaatgcaa    720

tgcagcaatt cacaagaagt gtattgataa agttatagca aagtgcacag gatcagctat    780

caatagccga gaaaccatgt tccacaagga gagattcaaa attgacatgc cacacagatt    840

taaagtctac aattacaaga gcccgacctt ctgtgaacac tgtgggaccc tgctgtgggg    900

actggcacgg caaggactca agtgtgatgc atgtggcatg aatgtgcatc atagatgcca    960

gacaaaggtg gccaaccttt gtggcataaa ccagaagcta atggctgaag cgctggccat   1020

gattgagagc actcaacagg ctcgctgctt aagagatact gaacagatct tcagagaagg   1080

tccggttgaa attggtctcc catgctccat caaaaatgaa gcaaggccgc catgtttacc   1140

gacaccggga aaaagagagc ctcagggcat ttcctgggag tctccgttgg atgaggtgga   1200

taaaatgtgc catcttccag aacctgaact gaacaaagaa agaccatctc tgcagattaa   1260

actaaaaatt gaggatttta tcttgcacaa aatgttgggg aaaggaagtt ttggcaaggt   1320

cttcctggca gaattcaaga aaaccaatca atttttcgca ataaaggcct taaagaaaga   1380

tgtggtcttg atggacgatg atgttgagtg cacgatggta gagaagagag ttctttcctt   1440

ggcctgggag catccgtttc tgacgcacat gttttgtaca ttccagacca aggaaaacct   1500

cttttttgtg atggagtacc tcaacggagg ggacttaatg taccacatcc aaagctgcca   1560

caagttcgac ctttccagag cgacgtttta tgctgctgaa atcattcttg gtctgcagtt   1620

ccttcattcc aaaggaatag tctacaggga cctgaagcta gataacatcc tgttagacaa   1680

agatggacat atcaagatcg cggattttgg aatgtgcaag gagaacatgt taggagatgc   1740

caagacgaat accttctgtg ggacacctga ctacatcgcc ccagagatct tgctgggtca   1800

gaaatacaac cactctgtgg actggtggtc cttcggggtt ctcctttatg aaatgctgat   1860

tggtcagtcg cctttccacg ggcaggatga ggaggagctc ttccactcca tccgcatgga   1920

caatcccttt tacccacggt ggctggagaa ggaagcaaag gaccttctgg tgaagctctt   1980

cgtgcgagaa cctgagaaga ggctgggcgt gaggggagac atccgccagc accctttgtt   2040

tcgggagatc aactgggagg aacttgaacg gaaggagatt gacccaccgt tccggccgaa   2100

agtgaaatca ccatttgact gcagcaattt cgacaaagaa ttcttaaacg agaagccccg   2160

gctgtcattt gccgacagag cactgatcaa cagcatggac cagaatatgt tcaggaactt   2220

ttccttcatg aaccccggga tggagcggct gatatcctga atcttgcccc tccagagaca   2280

ggaaagaatt tgccttctcc ctgggaactg gttcaagaga cactgcttgg gttccttttt   2340

caacttggaa aaagaaagaa acactcaaca ataaagactg agacccgttc gcccccatgt   2400

gacttttatc tgtagcagaa accaagtcta cttcactaat gacgatgccg tgtgtctcgt   2460

ctcctgacat gtctcacaga cgctcctgaa gttaggtcat tactaaccat agttatttac   2520

ttgaaagatg ggtctccgca cttggaaagg tttcaagact tgatactgca ataaattatg   2580

gctcttcacc tgggcgccaa ctgctgatca atgaaatgct tgttgaatca ggggcaaacg   2640

gagtacagac gtctcaagac tgaaacggcc ccattgcctg gtctagtagc ggatctcact   2700

cagccgcaga caagtaatca ctaacccgtt ttattctatt cctatctgtg gatgtgtaaa   2760

tggctggggg gccagccctg gataggtttt tatgggaatt ctttacaata aacatagctt   2820

gtaacttgag atctacaaat ccattcatcc tgattgggca tgaaatccat ggtcaagagg   2880

acaagtggaa agtgagaggg aaggtttgct agacaccttc gcttgttatc ttgtcaagat   2940

agaaaagata gtatcatttc acccttgcca gtaaaaacct ttccatccac ccattctcag   3000

cagactccag tattggcaca gtcactcact gccattctca cactataaca agaaaagaaa   3060

tgaagtgcat aagtctcctg ggaaaagaac cttaacccct tctcgtgcca tgactggtga   3120

tttcatgact cataagcccc tccgtaggca tcattcaaga tcaatggccc atgcatgctg   3180

tttgcagcag tcaattgagt tgaattagaa ttccaaccat acattttaaa ggtatttgtg   3240

ctgtgtgtat attttgataa aatgttgtga cttcatggca aacaggtgga tgtgtaaaaa   3300

tggaataaaa aaaaaaaaag agtc                                          3324


<210>  6365
<211>  706
<212>  PRT
<213>  Homo sapiens

<400>  6365

Met Ser Pro Phe Leu Arg Ile Gly Leu Ser Asn Phe Asp Cys Gly Ser 
1               5                   10                  15


Cys Gln Ser Cys Gln Gly Glu Ala Val Asn Pro Tyr Cys Ala Val Leu 
            20                  25                  30


Val Lys Glu Tyr Val Glu Ser Glu Asn Gly Gln Met Tyr Ile Gln Lys 
        35                  40                  45


Lys Pro Thr Met Tyr Pro Pro Trp Asp Ser Thr Phe Asp Ala His Ile 
    50                  55                  60


Asn Lys Gly Arg Val Met Gln Ile Ile Val Lys Gly Lys Asn Val Asp 
65                  70                  75                  80


Leu Ile Ser Glu Thr Thr Val Glu Leu Tyr Ser Leu Ala Glu Arg Cys 
                85                  90                  95


Arg Lys Asn Asn Gly Lys Thr Glu Ile Trp Leu Glu Leu Lys Pro Gln 
            100                 105                 110


Gly Arg Met Leu Met Asn Ala Arg Tyr Phe Leu Glu Met Ser Asp Thr 
        115                 120                 125


Lys Asp Met Asn Glu Phe Glu Thr Glu Gly Phe Phe Ala Leu His Gln 
    130                 135                 140


Arg Arg Gly Ala Ile Lys Gln Ala Lys Val His His Val Lys Cys His 
145                 150                 155                 160


Glu Phe Thr Ala Thr Phe Phe Pro Gln Pro Thr Phe Cys Ser Val Cys 
                165                 170                 175


His Glu Phe Val Trp Gly Leu Asn Lys Gln Gly Tyr Gln Cys Arg Gln 
            180                 185                 190


Cys Asn Ala Ala Ile His Lys Lys Cys Ile Asp Lys Val Ile Ala Lys 
        195                 200                 205


Cys Thr Gly Ser Ala Ile Asn Ser Arg Glu Thr Met Phe His Lys Glu 
    210                 215                 220


Arg Phe Lys Ile Asp Met Pro His Arg Phe Lys Val Tyr Asn Tyr Lys 
225                 230                 235                 240


Ser Pro Thr Phe Cys Glu His Cys Gly Thr Leu Leu Trp Gly Leu Ala 
                245                 250                 255


Arg Gln Gly Leu Lys Cys Asp Ala Cys Gly Met Asn Val His His Arg 
            260                 265                 270


Cys Gln Thr Lys Val Ala Asn Leu Cys Gly Ile Asn Gln Lys Leu Met 
        275                 280                 285


Ala Glu Ala Leu Ala Met Ile Glu Ser Thr Gln Gln Ala Arg Cys Leu 
    290                 295                 300


Arg Asp Thr Glu Gln Ile Phe Arg Glu Gly Pro Val Glu Ile Gly Leu 
305                 310                 315                 320


Pro Cys Ser Ile Lys Asn Glu Ala Arg Pro Pro Cys Leu Pro Thr Pro 
                325                 330                 335


Gly Lys Arg Glu Pro Gln Gly Ile Ser Trp Glu Ser Pro Leu Asp Glu 
            340                 345                 350


Val Asp Lys Met Cys His Leu Pro Glu Pro Glu Leu Asn Lys Glu Arg 
        355                 360                 365


Pro Ser Leu Gln Ile Lys Leu Lys Ile Glu Asp Phe Ile Leu His Lys 
    370                 375                 380


Met Leu Gly Lys Gly Ser Phe Gly Lys Val Phe Leu Ala Glu Phe Lys 
385                 390                 395                 400


Lys Thr Asn Gln Phe Phe Ala Ile Lys Ala Leu Lys Lys Asp Val Val 
                405                 410                 415


Leu Met Asp Asp Asp Val Glu Cys Thr Met Val Glu Lys Arg Val Leu 
            420                 425                 430


Ser Leu Ala Trp Glu His Pro Phe Leu Thr His Met Phe Cys Thr Phe 
        435                 440                 445


Gln Thr Lys Glu Asn Leu Phe Phe Val Met Glu Tyr Leu Asn Gly Gly 
    450                 455                 460


Asp Leu Met Tyr His Ile Gln Ser Cys His Lys Phe Asp Leu Ser Arg 
465                 470                 475                 480


Ala Thr Phe Tyr Ala Ala Glu Ile Ile Leu Gly Leu Gln Phe Leu His 
                485                 490                 495


Ser Lys Gly Ile Val Tyr Arg Asp Leu Lys Leu Asp Asn Ile Leu Leu 
            500                 505                 510


Asp Lys Asp Gly His Ile Lys Ile Ala Asp Phe Gly Met Cys Lys Glu 
        515                 520                 525


Asn Met Leu Gly Asp Ala Lys Thr Asn Thr Phe Cys Gly Thr Pro Asp 
    530                 535                 540


Tyr Ile Ala Pro Glu Ile Leu Leu Gly Gln Lys Tyr Asn His Ser Val 
545                 550                 555                 560


Asp Trp Trp Ser Phe Gly Val Leu Leu Tyr Glu Met Leu Ile Gly Gln 
                565                 570                 575


Ser Pro Phe His Gly Gln Asp Glu Glu Glu Leu Phe His Ser Ile Arg 
            580                 585                 590


Met Asp Asn Pro Phe Tyr Pro Arg Trp Leu Glu Lys Glu Ala Lys Asp 
        595                 600                 605


Leu Leu Val Lys Leu Phe Val Arg Glu Pro Glu Lys Arg Leu Gly Val 
    610                 615                 620


Arg Gly Asp Ile Arg Gln His Pro Leu Phe Arg Glu Ile Asn Trp Glu 
625                 630                 635                 640


Glu Leu Glu Arg Lys Glu Ile Asp Pro Pro Phe Arg Pro Lys Val Lys 
                645                 650                 655


Ser Pro Phe Asp Cys Ser Asn Phe Asp Lys Glu Phe Leu Asn Glu Lys 
            660                 665                 670


Pro Arg Leu Ser Phe Ala Asp Arg Ala Leu Ile Asn Ser Met Asp Gln 
        675                 680                 685


Asn Met Phe Arg Asn Phe Ser Phe Met Asn Pro Gly Met Glu Arg Leu 
    690                 695                 700


Ile Ser 
705


<210>  6366
<211>  692
<212>  DNA
<213>  Homo sapiens

<400>  6366
agtgcgccgg gcccgccagc cccgccagcc ccgccagccc cgccagcccc gccagtcccc     60

gcgcagtccc cgcgcagtcc ccgcgcagtc ccagcgccac cgggcagcag cggcgccgtg    120

ctcgctccag ggcgcaacca tgtcgccatt tcttcggatt ggcttgtcca actttgactg    180

cgggtcctgc cagtcttgtc agggcgaggc tgttaaccct tactgtgctg tgctcgtcaa    240

agagtatgtc gaatcagaga acgggcagat gtatatccag aaaaagccta ccatgtaccc    300

accctgggac agcacttttg atgcccatat caacaaggga agagtcatgc agatcattgt    360

gaaaggcaaa aacgtggacc tcatctctga aaccaccgtg gagctctact cgctggctga    420

gaggtgcagg aagaacaacg ggaagacaga aatatggaca caaaggacat gaatgaattt    480

gagacggaag gcttctttgc tttgcatcag cgccggggtg ccatcaagca ggcaaaggtc    540

caccacgtca agtgccacga gttcactgcc accttcttcc cacagcccac attttgctct    600

gtctgccacg agtttgtctg gggcctgaac aaacagggct accagtgccg acaatgcaat    660

gcagcaattc acaagaagtg tattgataaa gt                                  692


<210>  6367
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  6367

Met Ser Pro Phe Leu Arg Ile Gly Leu Ser Asn Phe Asp Cys Gly Ser 
1               5                   10                  15


Cys Gln Ser Cys Gln Gly Glu Ala Val Asn Pro Tyr Cys Ala Val Leu 
            20                  25                  30


Val Lys Glu Tyr Val Glu Ser Glu Asn Gly Gln Met Tyr Ile Gln Lys 
        35                  40                  45


Lys Pro Thr Met Tyr Pro Pro Trp Asp Ser Thr Phe Asp Ala His Ile 
    50                  55                  60


Asn Lys Gly Arg Val Met Gln Ile Ile Val Lys Gly Lys Asn Val Asp 
65                  70                  75                  80


Leu Ile Ser Glu Thr Thr Val Glu Leu Tyr Ser Leu Ala Glu Arg Cys 
                85                  90                  95


Arg Lys Asn Asn Gly Lys Thr Glu Ile Trp Thr Gln Arg Thr 
            100                 105                 110


<210>  6368
<211>  588
<212>  DNA
<213>  Homo sapiens

<400>  6368
agccccgcca gccccgccag tccccgcgca gtccccgcgc agtccccgcg cagtcccagc     60

gccaccgggc agcagcggcg ccgtgctcgc tccagggcgc aaccatgtcg ccatttcttc    120

ggattggctt gtccaacttt gactgcgggt cctgccagtc ttgtcagggc gaggctgtta    180

acccttactg tgctgtgctc gtcaaagagt atgtcgaatc agagaacggg cagatgtata    240

tccagaaaaa gcctaccatg tacccaccct gggacagcac ttttgatgcc catatcaaca    300

agggaagagt catgcagatc attgtgaaag gcaaaaacgt ggacctcatc tctgaaacca    360

ccgtggagct ctactcgctg gctgagaggt gcaggaagaa caacgggaag acagaaatat    420

gggtaacgtt gcataaagtg tatgcacata agggataagc atgatggtag ccgatgactg    480

gctcagaact cccatgtcaa tctgagggtg tgattacact ggcctcgggt caccaggctc    540

cctaccactt cctactggtg atttgataat ggcgatggtt attcttta                 588


<210>  6369
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  6369

Met Ser Pro Phe Leu Arg Ile Gly Leu Ser Asn Phe Asp Cys Gly Ser 
1               5                   10                  15


Cys Gln Ser Cys Gln Gly Glu Ala Val Asn Pro Tyr Cys Ala Val Leu 
            20                  25                  30


Val Lys Glu Tyr Val Glu Ser Glu Asn Gly Gln Met Tyr Ile Gln Lys 
        35                  40                  45


Lys Pro Thr Met Tyr Pro Pro Trp Asp Ser Thr Phe Asp Ala His Ile 
    50                  55                  60


Asn Lys Gly Arg Val Met Gln Ile Ile Val Lys Gly Lys Asn Val Asp 
65                  70                  75                  80


Leu Ile Ser Glu Thr Thr Val Glu Leu Tyr Ser Leu Ala Glu Arg Cys 
                85                  90                  95


Arg Lys Asn Asn Gly Lys Thr Glu Ile Trp Val Thr Leu His Lys Val 
            100                 105                 110


Tyr Ala His Lys Gly 
        115


<210>  6370
<211>  2047
<212>  DNA
<213>  Homo sapiens

<400>  6370
gttcatgtgt cttaattctt gattcagaaa agctatcaac tgtattctcc atatctcaaa     60

gttaacgtgt ccaaaataaa atgtctcatc ttctcatgcc atctagttct tcccgcagtg    120

ctcccatctt gtgaatgggg atggcctcct accatgggtt ggggccccaa accttgaggc    180

cgccctgctc ctccttttcc ctcccctcat cttcagtggc ttggtacatc ccatcaagag    240

atatcggaat ccctgcacgc tgccagggtc cttctgctgg tgccctccga ccatcaactg    300

gaagagtgaa gtcgccccca gtagtctctc ttcttctgca cttgctcctt acagtcctct    360

caacacaggg accagggtac cccctttcta ggtgtaaata agtctgctct gcactcaaag    420

ctgaagacag cacgtagacc cctcgggcgg tgtcctacct gaactccaag ttctcaccat    480

ggcctgtgga cagccccatg ggcacaccca cctcgtctgt cttctctacc ccttgctcaa    540

ctccacgcag cccatccgcc ttcccagaac gtgcttggca gctccgacct cacacccatg    600

tttcggccgg gaacgttcac ctgccattgt ctgtgtgact cagtcctctc ctcgtgcagg    660

tctttactca acgtcatttc acagagaccc ttcaggacca gcaaagccct ccctgccgcc    720

ccacccagca ctccccacct ccctcctctg cttagtttgt ttcatgggag tcacctggtg    780

tatttcatat tatattcttc tgctttcttg tctgtctcgt gcatctggac ctctgcacaa    840

aggatgggtt ttgtctcttt ggctgactgc agtgtcctaa gacacttagt gcctagtagc    900

tctagtaact gtttgttgaa tgaatgaatg agtgaatgga tgcatagtca ctaaatcaga    960

aatcgtggat actgtaatca tagaacatta ggtcataaat accaaggatc ctgaggaaga   1020

agaagaaaga atatctatga tttggacagc catttttcca attgtggaac attgtttagc   1080

atttcaaata atgaaaataa acacatatag aaggcttact atgtgctggg cattgttctg   1140

ttttatacat attaactcgt ttaatctgtg caatgcacgt aggagtttat ggagtttcct   1200

cataccttat ctcattcagt tcccaaaata ataccagcag attgtgggtg attacaacat   1260

tttcaaggat tcttccccag ggcagctgct tgtgggagag ctgaggtcta gaaaggagga   1320

gttgagagca ggaaaggaac caagcctgac cccaccccca tgccagcatt ttgatttatg   1380

gaaccctggg agaagagttt ctccaaaatg atacttcatg gcctccagca gatccccctc   1440

aaagaaacca acctgggaat gaccctctgt gtggagatca aggaggaaag aggcaagtga   1500

gcctttcttt tctcctgctc gtggacttag agtaagagtg tctgggacat ccaggtatat   1560

actatttcca tttttccttt tgacatcttc gatgatcaag atacctgcta aggatttgtt   1620

cagaaatcag aattagttgt aaggcagttg cctgaacaac tgaaagcgta atgaccccac   1680

agagagcact aaggcaacag aaagtacggc gaggtgggat tattaggttg gtgcaaaagt   1740

aattgtggtt tttgccaata cttttaatgg caaagttttt ttaaaaagta tttttagtag   1800

aggcagggtt tagccatgtt gatcaggctg gtcttgaact cctgacctca ggtgatccgc   1860

ctgtcttggc ctcccaaaat tctgggatta caggcatgag ccaccatgcc cagccttttt   1920

ttaaatttcc attactttta atggcaaaaa ctgcaaatta ctttcacacc aaattaatag   1980

gatatttgat gagttttaat ataattatcg tttttaccac aattgacctt cccctactct   2040

taccctc                                                             2047


<210>  6371
<211>  133
<212>  PRT
<213>  Homo sapiens

<400>  6371

Met Ala Cys Gly Gln Pro His Gly His Thr His Leu Val Cys Leu Leu 
1               5                   10                  15


Tyr Pro Leu Leu Asn Ser Thr Gln Pro Ile Arg Leu Pro Arg Thr Cys 
            20                  25                  30


Leu Ala Ala Pro Thr Ser His Pro Cys Phe Gly Arg Glu Arg Ser Pro 
        35                  40                  45


Ala Ile Val Cys Val Thr Gln Ser Ser Pro Arg Ala Gly Leu Tyr Ser 
    50                  55                  60


Thr Ser Phe His Arg Asp Pro Ser Gly Pro Ala Lys Pro Ser Leu Pro 
65                  70                  75                  80


Pro His Pro Ala Leu Pro Thr Ser Leu Leu Cys Leu Val Cys Phe Met 
                85                  90                  95


Gly Val Thr Trp Cys Ile Ser Tyr Tyr Ile Leu Leu Leu Ser Cys Leu 
            100                 105                 110


Ser Arg Ala Ser Gly Pro Leu His Lys Gly Trp Val Leu Ser Leu Trp 
        115                 120                 125


Leu Thr Ala Val Ser 
    130


<210>  6372
<211>  813
<212>  DNA
<213>  Homo sapiens

<400>  6372
ctggattcct gaaccaagat attatgcaag atgataaatg ttcatggctg gattaagctg     60

ctgcatcttg gacagccata gatctatggc tgtttacact ctgtagattt ggtgcatgat    120

tatttagtag gtcagatatt gcagttcagt tatctcataa acagctggtt ttatattctt    180

ttcccctgtg taacttatgc tgctgccttc atttcaatct atatactttc ttttcttttt    240

tttttttttg aggctggagt gcagtgatgc aatctcggct tactgaaacc tccgtctcca    300

gggttcaagc gattctcctg cctcagcctc atgagtagct gggctgggat tacagaggtg    360

catcaccacg cccggctgtt taatctgcac acttcctatg tggcttaaat ccatattgtc    420

ttagggtagt tcctttctca tcccccaatt tcctcctcta acgcatatca tggaagtagc    480

cataatctaa gattagttgc ttatattaat tattcaaaac ttcttcaacc tttccgtaga    540

tgaaggttaa actagtcttt agattttttg aagatattag tgattggctt cggctaccaa    600

acactttaat ttcaatcagc acatcattag gacgccaatg aagcagcact gatcctgagt    660

caggaaagaa ctcccggctt tcacaaaaac cattcaaagc agcctcctct gctcatctct    720

cccgctgccc ccatcagaaa atccataacc acaacctttc ccagccttta agctgcctct    780

ggagagtcag ggaagccaat ggcatcattg ttc                                 813


<210>  6373
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  6373

Met Lys Val Lys Leu Val Phe Arg Phe Phe Glu Asp Ile Ser Asp Trp 
1               5                   10                  15


Leu Arg Leu Pro Asn Thr Leu Ile Ser Ile Ser Thr Ser Leu Gly Arg 
            20                  25                  30


Gln 



<210>  6374
<211>  430
<212>  DNA
<213>  Homo sapiens

<400>  6374
gggaacaaaa agaatcaggg agacttttac cctcgaagag ttttcagact gaggagctat     60

gctgtctaca gactccaaga cagggtcaac agtggggtga gatcaacgaa cgctgctgtt    120

gttatttatg atatggagct ggatttcatg ttgactgaag tgtggaatat atacaaaata    180

cagccggagt gcagtggctc acacctgtaa ccccagcact ttgggaggcc gaggtgggtg    240

gatcacctga gaacattttt gggaagacaa gactcttttc ccctggtgtc agaagtaaag    300

acctacagat ataccagcag tctctcagca tcggtagcct cattagggag ctactgaata    360

gcagctaatg gtcttctgta gaacataagt tgaaacaata ctagatagaa tgattattac    420

aaaaacaacc                                                           430


<210>  6375
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  6375

Ser Val Glu Tyr Ile Gln Asn Thr Ala Gly Val Gln Trp Leu Thr Pro 
1               5                   10                  15


Val Thr Pro Ala Leu Trp Glu Ala Glu Val Gly Gly Ser Pro Glu Asn 
            20                  25                  30


Ile Phe Gly Lys Thr Arg Leu Phe Ser Pro Gly Val Arg Ser Lys Asp 
        35                  40                  45


Leu Gln Ile Tyr Gln Gln Ser Leu Ser Ile Gly Ser Leu Ile Arg Glu 
    50                  55                  60


Leu Leu Asn Ser Ser 
65


<210>  6376
<211>  6128
<212>  DNA
<213>  Homo sapiens

<400>  6376
ggagagggct gcgcgcttct cgccaagcaa gcgggaggcg cactggggcc gccgccgttc     60

ccgcgctcct ccctctcctc tgcacccact gtcacgctac ccgcccgcgg gggagcctcg    120

agagcctcca ggtgaattga aagtcgtttc cgggggagga cggagagggt gctgcagtcc    180

tggcatgccc tgaaactgca agtcgggcag aaacgacccg gcggaggagc agggcgcgca    240

gcgccctgcg cagcatcccc gggctgccag aagaggccac cactcggctg gcagccgcga    300

gcggcggccg aacctcggcc ccagactcgg gcccccggca cgctcgcccg ggagataccc    360

cttccccctc ttgcgcattt cgcagctgcg ctggtgtggg gcatgagagc gaggtggctc    420

caggtctccg cggagcagct gccagtggga gagcgaggag aggcgagggg gcggcagcct    480

cggcccgaaa cggagatcct ggggtcctaa atttgtggcc gattgcactg tgtcctggag    540

acggagtgga accacagccc agagcccctg ggaatcatcc ctgaaagact gcattacttc    600

tccatggagt cttcctcctc ctgcttattt tctttttgga acaaggcaaa ggcaatctgc    660

atgtaacatc accagaagat gcagaatgcc gcagaaccaa ggaacgcctt tctaatggaa    720

acagtcgtgg ttcagtttcc aagtcttccc gcaatatccc aaggagacac accctagggg    780

ggccccgaag ttccaaggaa atactgggaa tgcaaacatc tgagatggat cggaagagag    840

aagcgttcct agaacatctg aagcagaagt acccccacca cgcctctgca atcatgggtc    900

accaagagag gctgagagac cagacaagga gccccaaact gtctcacagt cctcaaccac    960

ccagtctggg tgacccggtc gagcatttat cagagacgtc cgctgattct ttggaagcca   1020

tgtctgaggg ggatgctcca accccttttt ccagaggcag ccggactcgt gcgagccttc   1080

ctgtggtgag gtcaaccaac cagacgaaag aaagatctct gggggttctc tatctccagt   1140

atggagatga aaccaagcag ctcaggatgc cgaatgaaat cacaagtgca gacacaatcc   1200

gtgctctctt cgtaagtgcc tttccacagc agctcaccat gaaaatgctg gaatcgccca   1260

gtgtcgccat ttacatcaaa gatgaaagca gaaatgtcta ttatgaatta aatgatgtaa   1320

ggaacattca agacagatca ctcctcaaag tgtacaacaa ggatcctgca catgcgttta   1380

atcacacacc aaaaactatg aatggagaca tgaggatgca gagagaactt gtttatgcaa   1440

gaggagatgg ccctggggcc cctcgccccg gatctactgc tcatccaccc catgcgattc   1500

caaattcccc accgtctact ccagtgcccc attccatgcc cccctccccg tccagaattc   1560

cttatggggg cacccgctcc atggttgttc ctggcaatgc caccatcccc agggacagaa   1620

tctccagcct gccagtctcc agacccatct ctccaagccc aagcgccatt ttagaaagaa   1680

gagatgtcaa gcctgatgaa gacatgagtg gcaaaaacat tgcaatgtac agaaatgagg   1740

gtttctatgc tgatccttac ctttatcacg agggacggat gagcatagcc tcatcccatg   1800

gtggacaccc actggatgtc cccgaccaca tcattgcata tcaccgcacc gccatccggt   1860

cagcgagtgc ttattgtaac ccctcaatgc aagcggaaat gcatatggaa caatcactgt   1920

acagacagaa atcaaggaaa tatccggata gccatttgcc tacactgggc tccaaaacac   1980

cccctgcctc tcctcacaga gtcagtgacc tgaggatgat agacatgcac gctcactata   2040

atgcccacgg cccccctcac accatgcagc cagaccgggc ctctccgagc cgccaggcct   2100

ttaaaaagga gccaggcacc ttggtgtata tagaaaagcc acggagcgct gcaggattat   2160

ccagccttgt agacctcggc cctcctctaa tggagaagca agtttttgcc tacagcacgg   2220

cgacaatacc caaagacaga gagaccagag agaggatgca agccatggag aaacagattg   2280

ccagtttaac tggccttgtt cagtctgcgc tttttaaagg gcccattaca agttatagca   2340

aagatgcgtc tagcgagaaa atgatgaaaa ccacagccaa caggaaccac acagatagtg   2400

caggaacgcc ccatgtgtct ggtgggaaga tgctcagtgc tctggagtcc acggtgcctc   2460

ccagccagcc tccacctgtg ggcacctcag ccatccacat gagcctgctt gagatgaggc   2520

ggagcgtggc ggaactcagg ctccagctcc agcagatgcg gcagctccag ctgcagaacc   2580

aggagttgct gagggcaatg atgaagaagg ccgagctgga aatcagtggc aaagtgatgg   2640

aaacaatgaa gagactggag gatcccgtgc agcgacagcg cgtcctagtg gagcaagaga   2700

gacaaaaata tcttcatgag gaagagaaga tcgtcaagaa gttgtgcgag ttggaagact   2760

ttgttgaaga cttgaagaag gactccacgg cagccagccg attggttact ctgaaagacg   2820

tggaagacgg ggctttcctc ctgcgtcaag tgggagaggc tgtagctacc ctgaaaggag   2880

aatttccaac cttacaaaac aagatgcgag ccatcctgcg catagaagtg gaggccgtgc   2940

ggtttctgaa ggaggagcca cacaagctgg acagtctcct gaagcgtgtg cgcagcatga   3000

cagacgtcct gaccatgctg cggagacatg tcactgatgg gctcctgaaa ggcacggacg   3060

cagcccaagc cgcacagtac atggctatgg aaaaggccac agccgcagaa gtcctgaaga   3120

gtcaggagga ggcagcccac acctccggcc agcccttcca cagcacaggt gcccctggcg   3180

atgcgaagtc ggaagtggtg cctttgtccg gcatgatggt tcgccacgcg cagagctccc   3240

ctgtggtcat ccagccctcc cagcactccg tggccctgct gaaccctgct cagaacttgc   3300

ctcacgtggc cagctcccca gccgtccccc aggaagcaac ctccactctg cagatgtcgc   3360

aggctccgca gtccccacag atacccatga atgggtctgc catgcagagc ttgttcattg   3420

aagaaatcca cagtgtgagt gccaagaaca gggcagtgtc tatcgagaaa gcagaaaaga   3480

aatgggagga aaaaaggcaa aatctggatc actataatgg gaaagagttt gagaagctcc   3540

tagaagaagc tcaggccaat atcatgaagt caataccaaa tctggagatg ccgccagcca   3600

caggcccact gccaagggga gatgccccag tggacaaggt ggaactttca gaagattctc   3660

caaattcgga acaggacttg gaaaagctgg ggggaaagtc gccccctcct cctccgccac   3720

ctcctcgtcg aagctacctg ccaggatcgg gactcaccac cacgaggtca ggcgatgtgg   3780

tctacaccgg cagaaaggag aacatcaccg ctaaggcaag cagtgaagat gctggaccaa   3840

gcccacagac cagagctaca aaatatccag cagaggagcc tgcttcagcc tggaccccat   3900

ccccaccgcc tgtcaccacc tcctcctcaa aggatgagga ggaagaagaa gaagaaggag   3960

acaaaataat ggcagaactc cagggctcca gcggggcccc acagacgagc aggatgcctg   4020

tccccatgag tgccaagaac agacccggaa ccctggacaa acccggcaag cagtccaaac   4080

tgcaggatcc ccgccaatat cgtcaggcta atggaagtgc taagaaatct ggtggggact   4140

ttaagcctac ttccccctcc ttacctgctt ctaagattcc agccctttct cccagctctg   4200

ggaaaagcag ttctctgccc tcttctagtg gtgacagctc taacctccct aatccacctg   4260

ctactaaacc atcgattgct tctaaccctc tcagccccca aacaggacca cctgctcact   4320

ctgcctccct catcccttct gtctctaatg gctctttgaa gtttcagagc ctcactcata   4380

caggtaaagg tcaccatctt tcattctcac cgcagagtca aaatggccga gcaccccctc   4440

ctttgtcatt ttcctcctcc cctccttctc ctgcctcctc cgtctcactg aatcaaggtg   4500

ccaagggcac caggaccatc catactccca gcctcaccag ctacaaggca cagaatggaa   4560

gttcaagcaa agccacccca tccacagcaa aagaaacctc ttaaaggtca aatcctatta   4620

ggcacaagtc ggagttacat ttaaaaaaaa ttaacagtct acaacaactg ttttcacaag   4680

agaatgtaac atattgctgt atcgtttgag gcttaatgct aaatatgtgc taaatactgg   4740

attaatagat ttcagtaaag ctcgttcgtt ttgtttggtt ttctttttac ctagttgcta   4800

tagtgtctac agtctatact caatacctat aaaatgcagt aagcatgtgt tacagaaaga   4860

ggttctggtg ggagagaaag gtgcgtgtga gacaggagaa ttgtcttaag catataaaac   4920

atgtatgatt ccagaatttt agtatgtttt gtataaaact atttttcatt acggagacta   4980

gaagtgaaca gagaattaca caagtgtgac tatacaaatt gtaaaacaga tactataata   5040

tttcctttta ttttagtgtt atttagcttt attacagatt tctatttttg tcaaaacttc   5100

atggttcctt tcaagatctt ttttgccaaa acattttgat actatagcat tgtacatttg   5160

aaagtagtgt tctagactat aaaaccaatg aacttctaca tgagccctac agacaggcat   5220

gtgtagaagg caatttatca aacctattgc actgccatga aaagtgtgta taataatttg   5280

ctagcccaag caagctagtt ttctttgctt gcttcttttc tttctttttt ccttcctttt   5340

tttttttttt ttctttttta acatgttgag attctctagt tgttttcttt ggcgtatcta   5400

accccttctt ttgttttctg agacctggta acccacgctc ttgcattgtg gattttaaaa   5460

tgtatactct gtacggttct gtaaaccgaa aaacttttgt aaatatataa atatacatag   5520

acataaaaat actgtatgtg acagcacata gagtagtttt cccacaccaa agttaatttt   5580

tatgcatgct ttaaaagtat atatcgggac cggcagaaat ggaagtatcc atacattttt   5640

aaaaagcaac aagtttgcac agctagagtg tttttgtaaa taaatgtatt tgtataacac   5700

agtcatgtaa tatacagaac tataagcaga gactttgcaa aactaaataa agggctgcat   5760

gcttattatt ttttgtacct tgtcactata actacttcct agtcaaagaa cgaaatgtaa   5820

ctgttaccga gttaaatgtt tttccgcttt gagggatgta accacatcca ctcagaggac   5880

actacttttc tgaaagctct ggggtgacta atgatgagtt cctaataaat taattgcaag   5940

tgtggtgcct tggatgtggc ctgttggctc gctttcttct ctgtggctta tcaaggtgta   6000

gatgacagaa agcaaacctg gatacagagt ttccaccctc agttcctgga ggggctctta   6060

ttattttctc tctttttaaa aaacttccag tagaagtaaa gtggaaataa aatgtcttta   6120

tcacttgg                                                            6128


<210>  6377
<211>  1264
<212>  PRT
<213>  Homo sapiens

<400>  6377

Met Gln Thr Ser Glu Met Asp Arg Lys Arg Glu Ala Phe Leu Glu His 
1               5                   10                  15


Leu Lys Gln Lys Tyr Pro His His Ala Ser Ala Ile Met Gly His Gln 
            20                  25                  30


Glu Arg Leu Arg Asp Gln Thr Arg Ser Pro Lys Leu Ser His Ser Pro 
        35                  40                  45


Gln Pro Pro Ser Leu Gly Asp Pro Val Glu His Leu Ser Glu Thr Ser 
    50                  55                  60


Ala Asp Ser Leu Glu Ala Met Ser Glu Gly Asp Ala Pro Thr Pro Phe 
65                  70                  75                  80


Ser Arg Gly Ser Arg Thr Arg Ala Ser Leu Pro Val Val Arg Ser Thr 
                85                  90                  95


Asn Gln Thr Lys Glu Arg Ser Leu Gly Val Leu Tyr Leu Gln Tyr Gly 
            100                 105                 110


Asp Glu Thr Lys Gln Leu Arg Met Pro Asn Glu Ile Thr Ser Ala Asp 
        115                 120                 125


Thr Ile Arg Ala Leu Phe Val Ser Ala Phe Pro Gln Gln Leu Thr Met 
    130                 135                 140


Lys Met Leu Glu Ser Pro Ser Val Ala Ile Tyr Ile Lys Asp Glu Ser 
145                 150                 155                 160


Arg Asn Val Tyr Tyr Glu Leu Asn Asp Val Arg Asn Ile Gln Asp Arg 
                165                 170                 175


Ser Leu Leu Lys Val Tyr Asn Lys Asp Pro Ala His Ala Phe Asn His 
            180                 185                 190


Thr Pro Lys Thr Met Asn Gly Asp Met Arg Met Gln Arg Glu Leu Val 
        195                 200                 205


Tyr Ala Arg Gly Asp Gly Pro Gly Ala Pro Arg Pro Gly Ser Thr Ala 
    210                 215                 220


His Pro Pro His Ala Ile Pro Asn Ser Pro Pro Ser Thr Pro Val Pro 
225                 230                 235                 240


His Ser Met Pro Pro Ser Pro Ser Arg Ile Pro Tyr Gly Gly Thr Arg 
                245                 250                 255


Ser Met Val Val Pro Gly Asn Ala Thr Ile Pro Arg Asp Arg Ile Ser 
            260                 265                 270


Ser Leu Pro Val Ser Arg Pro Ile Ser Pro Ser Pro Ser Ala Ile Leu 
        275                 280                 285


Glu Arg Arg Asp Val Lys Pro Asp Glu Asp Met Ser Gly Lys Asn Ile 
    290                 295                 300


Ala Met Tyr Arg Asn Glu Gly Phe Tyr Ala Asp Pro Tyr Leu Tyr His 
305                 310                 315                 320


Glu Gly Arg Met Ser Ile Ala Ser Ser His Gly Gly His Pro Leu Asp 
                325                 330                 335


Val Pro Asp His Ile Ile Ala Tyr His Arg Thr Ala Ile Arg Ser Ala 
            340                 345                 350


Ser Ala Tyr Cys Asn Pro Ser Met Gln Ala Glu Met His Met Glu Gln 
        355                 360                 365


Ser Leu Tyr Arg Gln Lys Ser Arg Lys Tyr Pro Asp Ser His Leu Pro 
    370                 375                 380


Thr Leu Gly Ser Lys Thr Pro Pro Ala Ser Pro His Arg Val Ser Asp 
385                 390                 395                 400


Leu Arg Met Ile Asp Met His Ala His Tyr Asn Ala His Gly Pro Pro 
                405                 410                 415


His Thr Met Gln Pro Asp Arg Ala Ser Pro Ser Arg Gln Ala Phe Lys 
            420                 425                 430


Lys Glu Pro Gly Thr Leu Val Tyr Ile Glu Lys Pro Arg Ser Ala Ala 
        435                 440                 445


Gly Leu Ser Ser Leu Val Asp Leu Gly Pro Pro Leu Met Glu Lys Gln 
    450                 455                 460


Val Phe Ala Tyr Ser Thr Ala Thr Ile Pro Lys Asp Arg Glu Thr Arg 
465                 470                 475                 480


Glu Arg Met Gln Ala Met Glu Lys Gln Ile Ala Ser Leu Thr Gly Leu 
                485                 490                 495


Val Gln Ser Ala Leu Phe Lys Gly Pro Ile Thr Ser Tyr Ser Lys Asp 
            500                 505                 510


Ala Ser Ser Glu Lys Met Met Lys Thr Thr Ala Asn Arg Asn His Thr 
        515                 520                 525


Asp Ser Ala Gly Thr Pro His Val Ser Gly Gly Lys Met Leu Ser Ala 
    530                 535                 540


Leu Glu Ser Thr Val Pro Pro Ser Gln Pro Pro Pro Val Gly Thr Ser 
545                 550                 555                 560


Ala Ile His Met Ser Leu Leu Glu Met Arg Arg Ser Val Ala Glu Leu 
                565                 570                 575


Arg Leu Gln Leu Gln Gln Met Arg Gln Leu Gln Leu Gln Asn Gln Glu 
            580                 585                 590


Leu Leu Arg Ala Met Met Lys Lys Ala Glu Leu Glu Ile Ser Gly Lys 
        595                 600                 605


Val Met Glu Thr Met Lys Arg Leu Glu Asp Pro Val Gln Arg Gln Arg 
    610                 615                 620


Val Leu Val Glu Gln Glu Arg Gln Lys Tyr Leu His Glu Glu Glu Lys 
625                 630                 635                 640


Ile Val Lys Lys Leu Cys Glu Leu Glu Asp Phe Val Glu Asp Leu Lys 
                645                 650                 655


Lys Asp Ser Thr Ala Ala Ser Arg Leu Val Thr Leu Lys Asp Val Glu 
            660                 665                 670


Asp Gly Ala Phe Leu Leu Arg Gln Val Gly Glu Ala Val Ala Thr Leu 
        675                 680                 685


Lys Gly Glu Phe Pro Thr Leu Gln Asn Lys Met Arg Ala Ile Leu Arg 
    690                 695                 700


Ile Glu Val Glu Ala Val Arg Phe Leu Lys Glu Glu Pro His Lys Leu 
705                 710                 715                 720


Asp Ser Leu Leu Lys Arg Val Arg Ser Met Thr Asp Val Leu Thr Met 
                725                 730                 735


Leu Arg Arg His Val Thr Asp Gly Leu Leu Lys Gly Thr Asp Ala Ala 
            740                 745                 750


Gln Ala Ala Gln Tyr Met Ala Met Glu Lys Ala Thr Ala Ala Glu Val 
        755                 760                 765


Leu Lys Ser Gln Glu Glu Ala Ala His Thr Ser Gly Gln Pro Phe His 
    770                 775                 780


Ser Thr Gly Ala Pro Gly Asp Ala Lys Ser Glu Val Val Pro Leu Ser 
785                 790                 795                 800


Gly Met Met Val Arg His Ala Gln Ser Ser Pro Val Val Ile Gln Pro 
                805                 810                 815


Ser Gln His Ser Val Ala Leu Leu Asn Pro Ala Gln Asn Leu Pro His 
            820                 825                 830


Val Ala Ser Ser Pro Ala Val Pro Gln Glu Ala Thr Ser Thr Leu Gln 
        835                 840                 845


Met Ser Gln Ala Pro Gln Ser Pro Gln Ile Pro Met Asn Gly Ser Ala 
    850                 855                 860


Met Gln Ser Leu Phe Ile Glu Glu Ile His Ser Val Ser Ala Lys Asn 
865                 870                 875                 880


Arg Ala Val Ser Ile Glu Lys Ala Glu Lys Lys Trp Glu Glu Lys Arg 
                885                 890                 895


Gln Asn Leu Asp His Tyr Asn Gly Lys Glu Phe Glu Lys Leu Leu Glu 
            900                 905                 910


Glu Ala Gln Ala Asn Ile Met Lys Ser Ile Pro Asn Leu Glu Met Pro 
        915                 920                 925


Pro Ala Thr Gly Pro Leu Pro Arg Gly Asp Ala Pro Val Asp Lys Val 
    930                 935                 940


Glu Leu Ser Glu Asp Ser Pro Asn Ser Glu Gln Asp Leu Glu Lys Leu 
945                 950                 955                 960


Gly Gly Lys Ser Pro Pro Pro Pro Pro Pro Pro Pro Arg Arg Ser Tyr 
                965                 970                 975


Leu Pro Gly Ser Gly Leu Thr Thr Thr Arg Ser Gly Asp Val Val Tyr 
            980                 985                 990


Thr Gly Arg Lys Glu Asn Ile Thr Ala Lys Ala Ser Ser Glu Asp Ala 
        995                 1000                1005


Gly Pro Ser Pro Gln Thr Arg Ala Thr Lys Tyr Pro Ala Glu Glu Pro 
    1010                1015                1020


Ala Ser Ala Trp Thr Pro Ser Pro Pro Pro Val Thr Thr Ser Ser Ser 
1025                1030                1035                1040


Lys Asp Glu Glu Glu Glu Glu Glu Glu Gly Asp Lys Ile Met Ala Glu 
                1045                1050                1055


Leu Gln Gly Ser Ser Gly Ala Pro Gln Thr Ser Arg Met Pro Val Pro 
            1060                1065                1070


Met Ser Ala Lys Asn Arg Pro Gly Thr Leu Asp Lys Pro Gly Lys Gln 
        1075                1080                1085


Ser Lys Leu Gln Asp Pro Arg Gln Tyr Arg Gln Ala Asn Gly Ser Ala 
    1090                1095                1100


Lys Lys Ser Gly Gly Asp Phe Lys Pro Thr Ser Pro Ser Leu Pro Ala 
1105                1110                1115                1120


Ser Lys Ile Pro Ala Leu Ser Pro Ser Ser Gly Lys Ser Ser Ser Leu 
                1125                1130                1135


Pro Ser Ser Ser Gly Asp Ser Ser Asn Leu Pro Asn Pro Pro Ala Thr 
            1140                1145                1150


Lys Pro Ser Ile Ala Ser Asn Pro Leu Ser Pro Gln Thr Gly Pro Pro 
        1155                1160                1165


Ala His Ser Ala Ser Leu Ile Pro Ser Val Ser Asn Gly Ser Leu Lys 
    1170                1175                1180


Phe Gln Ser Leu Thr His Thr Gly Lys Gly His His Leu Ser Phe Ser 
1185                1190                1195                1200


Pro Gln Ser Gln Asn Gly Arg Ala Pro Pro Pro Leu Ser Phe Ser Ser 
                1205                1210                1215


Ser Pro Pro Ser Pro Ala Ser Ser Val Ser Leu Asn Gln Gly Ala Lys 
            1220                1225                1230


Gly Thr Arg Thr Ile His Thr Pro Ser Leu Thr Ser Tyr Lys Ala Gln 
        1235                1240                1245


Asn Gly Ser Ser Ser Lys Ala Thr Pro Ser Thr Ala Lys Glu Thr Ser 
    1250                1255                1260


<210>  6378
<211>  559
<212>  DNA
<213>  Homo sapiens

<400>  6378
ctcttcagac atcctcacgt tgctgtaaaa cagcaccggg ctgagtgaag agaaatgtca     60

caaggaatac aagaggacgc cttcaaacag agatagcgga gacagttaca ctctgaatta    120

gagtctagct ttggagagga tttatttttc ttttgttact tacatcctgg atttgctttt    180

ttttttttaa aggcagcttt gttttttact atttctagta aagcatggac atttgaagaa    240

ataaatataa aaggaagatt tctcaaagat ttgtcctgtt gagtaatgaa gcataccctg    300

aggacccagg gagtagaact agatcagtct ttctttttga gcaaaaaagc ctaatttgaa    360

attcaggatt acttttaaaa tatcactcaa aaacaaggca aaggcaatct gcatgtaaca    420

tcaccagaag atgcagaatg ccgcagaacc aaggaacgcc tttctaatgg aaacagtcgt    480

ggttcagttt ccaagtcttc ccgcaatatc ccaaggagac acaccctagg ggggccccga    540

agttccaagg aaatactgg                                                 559


<210>  6379
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  6379

Met Gln Asn Ala Ala Glu Pro Arg Asn Ala Phe Leu Met Glu Thr Val 
1               5                   10                  15


Val Val Gln Phe Pro Ser Leu Pro Ala Ile Ser Gln Gly Asp Thr Pro 
            20                  25                  30


<210>  6380
<211>  3653
<212>  DNA
<213>  Homo sapiens

<400>  6380
ttttttaact tttaatttaa gttcaggggt atgtgtgcag atttgttaca taggtaaact     60

tgtgtcatgg ggctttgttg tacagattgt ttcatcaccc aggtattatt ttattttcat    120

tttagttttt taaatttctt tttagaggcg gggtctcact gtgttttgcc caggctggtc    180

tcgaactcct cctggtctca agcaatcctc tcgcctctgc ctccccaagt gttgggatta    240

taggcatgag ctactgcact cagcccacca tttgttttaa aaagggtgga tcctatttgt    300

ataaaaagcc atgtgcattt tctgtgtact tgtctacaca ttaatttcca ggctgggcgt    360

ggtggctcac gcttgtaatc ccagcacttt gggaggccaa ggggaggcag atcatgaggt    420

taggagatcg aaaccatcct ggctaacacg gtgaaacccc gtctctacta aaaatacaaa    480

aacaaaatta gcagggtgtt gtggcgggcg cctgtagtcc cagctactca ggaggctgag    540

gcaggagaat ggcatgaacc cgggaggtgg agcttgcagt gagctgagat tgcgccactg    600

ccctccagcc tgggcaacaa agcaagactc catctcaaaa aaaaaaaaaa aaaaaaaaaa    660

aaatgtccct catacctaaa ccttacctct tgctaatttg ctgagggttc attttagata    720

aaaggtgttt aggttttcat attatgtttg taactgtata gctatgattc agtttcctaa    780

atgaaaaaag aaactgtttt aatgtacaga ctatttagat ttgaaaagac tgtgagagct    840

ttttctttta tagcaagaca agtcaagaat agaaggcaca ctgcgagagg gatgtctttt    900

gaaagaaaag aaacactact ttttatattc tcaaatcact gaagaaagct ttagacataa    960

tttcaaacac tagctcctgt ttaattcaga tgcacagaat gcattaaaac cacgagtgta   1020

gtggacgtga tttatacatt ctcttagcac aaatcagtac ctatcttcac tgtaattaga   1080

cttttcttcc tttctccttc tcaaaagcta cttttgaaac cttatgtttt ccctggacat   1140

attttctgta cttcataaaa tagctcagtt ctgcaactaa ctgcaaatat ttgcaaaagg   1200

gaacaaatgt aaaataaacg tcccctaatg cagtgtttgg tgaagaaaca tatgtctgac   1260

attagttggt taacctgaaa aatagtaaga aacaactcta cttaggggaa agggggtaga   1320

attgagcccg tactgtgcaa atcaagagaa agctataatt tacgcaattt ttattaaaga   1380

gaatacaagt gctgtaggct tggggtggtg ctaggtcata tttaagccta attgagcttt   1440

ttctatatca ttagaaaaat gggccaagtt tcctatatta tagggtaaat acaacatttt   1500

cttcctgcaa atattaaata ccactggctt tttaagacgt aaacatccaa atctcaaatg   1560

tctttattca tgccaatgca atacaataaa aatattcccc atatacactt aaatcactgc   1620

aagtaagcct tagaatcccc acaagtatta ttacttacta tatctcagaa actttcacac   1680

acattatttc aaatatagtt ctcccaaaaa aaccctgcgg agagatacct gtaaaccaag   1740

gctgagacta gcctagacag ttcgttcttt agacaacagg agtggagatt tgaacccagc   1800

tattgtgact caagcaagcc tagggcatgt ttctgagatc tctaaggtgt gcgctgtgaa   1860

accggtggct cattttatgg gttggatttc caaacacgac tatcacaatc atgccaggaa   1920

tcaatgactg acttcttgcc tccgtggcct gaagttctcc tctgcacctc ctaccttttt   1980

gccatttcag tgatgcacca aagggtggag ttgaagaaca tcagttttgc tgctgcttgt   2040

tggcaatact ctcaaaaagg cgtggggagg gagaggtgta actcacccct gaagtcaagc   2100

ctggagatta cttgtcagga atgtcaaaag catttgttaa gcaaccttct tcctggcatt   2160

ttaagaagaa agccgcatac atagatcaaa tcccttcctt cagaaacctg tactctctga   2220

acagagcctt ggaattcagc ctagagaaag aatacttggt ggttcataga acttggttca   2280

caaaagagtg cttgctgccc acgcattttg cacaatgact cccaaacaca cagaatgcac   2340

attggcaaca attttacgcg tgtttccaaa agtgctgact ggaattgaag ggacacattt   2400

ggcacttttt ttttttgaaa tggggttgca ctccagcctg ggcgacagag tgagactatg   2460

tctcaaaaaa attaaattaa aattaaaatt gagcctgatg tggtggcaca tgcctgtagt   2520

tccagctatg caggaagtta agatgggagg atcccttgag cttgggagat caaggctgca   2580

gtgagctgtg attgtaacta ctgcattcta gcctaagaaa cagaaagaga cactgtctca   2640

aaaaaaaaaa aaaaaaaaaa acaagaaaaa aaaagaaaga aaaaaacaga tcagaggccc   2700

tggcctgggg tcagtttctc cagaaaggcc tgcacaatgg agttttcatg taaaaaattt   2760

cttacatcct gattttaaaa aatcagatga tcaggaaaca ttgagttccg attcctttgt   2820

tacaacctcc actaaagcta agtaacagct gctgtattaa gatggggctc cccctctcca   2880

tcccacacct gcctccctta catgcctaac tcctgttgta aatagggacc ctaatctgat   2940

gtttttgtag tccctttcct aggggcactg tggggaggtg gaaggaattt cacctttgtt   3000

gttggacaga cttagatttg agaactggtt ctactactta ctgtttgtgt ggtctgggac   3060

aagtcacttg gtccaagtaa gcttctgcat ctgttaaaaa aaaaaaaaaa aaaaaaaaag   3120

gggcggggag ctaagaattc ctgcccagca agttggtttg cagatcagag gcagtgtgtg   3180

agaagtactt aacccagcac ctggcatata gtagatgttc aggacatcgt agcaggaata   3240

agggagacat ctcacaaaac attttgtgag aaaggatcag tttctatcta gtcaatgtct   3300

taaacattca taggttgttc atggtgggag ctgctcgagg aatcatccta gttttatgga   3360

ggaggaatct gaagctggag gaattgtctc cttcaagatt acttagttaa aggcaaacag   3420

gttcatagcc agtggctctt caccaaccca caaaaaggcc tcagattata attttgaaga   3480

ttaagtatat gaaagtgcta tttgagtgat taagtgtaag catcagatca ttttgaactg   3540

gtgagatggc tcacacctgg aattccagca ctttgggagg cccaagaggg aggattgttt   3600

gagcccagga gttcaagacc aacctgggca acattgtgag agcctgtccc tac          3653


<210>  6381
<211>  89
<212>  PRT
<213>  Homo sapiens

<400>  6381

Met Thr Pro Lys His Thr Glu Cys Thr Leu Ala Thr Ile Leu Arg Val 
1               5                   10                  15


Phe Pro Lys Val Leu Thr Gly Ile Glu Gly Thr His Leu Ala Leu Phe 
            20                  25                  30


Phe Phe Glu Met Gly Leu His Ser Ser Leu Gly Asp Arg Val Arg Leu 
        35                  40                  45


Cys Leu Lys Lys Ile Lys Leu Lys Leu Lys Leu Ser Leu Met Trp Trp 
    50                  55                  60


His Met Pro Val Val Pro Ala Met Gln Glu Val Lys Met Gly Gly Ser 
65                  70                  75                  80


Leu Glu Leu Gly Arg Ser Arg Leu Gln 
                85


<210>  6382
<211>  1555
<212>  DNA
<213>  Homo sapiens

<400>  6382
caccatttgt tttaaaaagg gtggatccta tttgtataaa aagccatgtg cattttctgt     60

gtacttgtct acacattaat ttccatttct ggaatgatgt ccaataaatc agagagaggg    120

actagaagac taatgaggac agaagctttt attcttaaca cctatatttt gctaccattt    180

atattgtcat catatgcata taacatttta acatttaaaa actagtttaa acagaaatgg    240

ttgccctgga atgtggcctg tgttctttca agggaggcca gcagtttcta cagtggctga    300

gatggtacct tcatctcaca cacctacgca ggagtgcatt tgtgctttga tgtggttgtc    360

ccttgaagaa ggaagcagtt ctctttttct tttttccctt ttccattata ggatcagtca    420

cttcttgggg cattagtagt ctcatttcca gtggcatctt cccttggcaa aaggaatccc    480

agataggacc tcatctttct aaacaaatgc tgttttgggt cctaaccatc ccatgtttgc    540

tttgaatatg tttaagttgc ctggaattat caacaaaaga attaaattta ttgtaggtca    600

gggcatcttt tgactcattg tataaaacat tcactttaaa tgtataccga aatgtccttt    660

atgtaatttt ctttaaagac tgccactggg tggaacccac tgggcccagt gagaactacg    720

gaaaagagac ccattcttgc cctcattgtt agtgtccaca tccggattta cctaaacccc    780

acccaggtgg catttgcata gtaatgaaaa accggtattt tctagctgtg aatcacactt    840

caaatcctga gcggctgact gtcaggggtg cgtcaggcct gcttgctggg agaatggacg    900

agctggttgt ggagcgggcg ggtcccgcca cccgtgggct cagcactgga ctgctcccag    960

aacattaaag gtctggctga tgttccatgc cacatctgga catgaagacc catgtctgcc   1020

cttctgtaga agggccaaag aagaaaggag gcatcacatg tttctgctgt ggggggccct   1080

tccgagcagc agacaggagc aaggtacagg agtggcctga ttctggggtt tccctgcccc   1140

ccctggggtc cctaaactgc tgtgtgatat gtttctaact atctggacag ctcacccaag   1200

agtcagttgt tcccagtcgc ttcttgctga ggataagcca aaagagggcc gggggccaat   1260

ctggtttctt tcaagtgaaa ttatgcttct caagcagaga atgattgccc acagcagtta   1320

aaccttgttt aatggtaatt aaattgcttt tcttcacttt gaaaaatctc ttaattttct   1380

gtacaaaggc aggaagcatt tttctttgat tctacaggat gtttctaagt atggtgtaat   1440

cagttcatct taccttgccg ggctctgaaa gaatgagtgt gtgggatcag atttagaaat   1500

gcctcaaagg ttagaaagcc gagtgctgcc gattaactca agctcagatg accaa        1555


<210>  6383
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  6383

Met Cys Ile Phe Cys Val Leu Val Tyr Thr Leu Ile Ser Ile Ser Gly 
1               5                   10                  15


Met Met Ser Asn Lys Ser Glu Arg Gly Thr Arg Arg Leu Met Arg Thr 
            20                  25                  30


Glu Ala Phe Ile Leu Asn Thr Tyr Ile Leu Leu Pro Phe Ile Leu Ser 
        35                  40                  45


Ser Tyr Ala Tyr Asn Ile Leu Thr Phe Lys Asn 
    50                  55


<210>  6384
<211>  2113
<212>  DNA
<213>  Homo sapiens

<400>  6384
gatactgggg aactataaat gtctccgtcc aactctgttc aactctaatt tttttttttt     60

tttgagacgg agtcttactc tgtcacccag gctggagtgc aatgacgtaa tcttggctca    120

cagcaacctc tgcctcctgg gttcaagtga ttctcctgcc tcagcctccc aagtagctgg    180

gattacagga gcccgccacc atgcccagct aatttttgta ttttttagta gacacagggt    240

ttcaccatgt tggccaggct ggtctcgaac tcctgacctc aagccatcca cctccctcgg    300

cttcccagag tgctgggatt acaggcatga gccatgacac ccggcctgta attttcttta    360

aagactgcca ctgggtggaa cccactgggc ccagtgagaa ctacggaaaa gagacccatt    420

cttgccctca ttgttagtgt ccacatccgg atttacctaa accccaccca ggtggcattt    480

gcatagtaat gaaaaaccgg tattttctag ctgtgaatca cacttcaaat cctgagcggc    540

tgactgtcag gggtgcgtca ggcctgcttg ctgggagaat ggacgagctg gttgtggagc    600

gggcgggtcc cgccacccgt gggctcagca ctggactgct cccagaacat taaaggtctg    660

gctgatgttc catgccacat ctggacatga agacccatgt ctgcccttct gtagaagggc    720

caaagaagaa aggaggcatc acatgtttct gctgtggggg gcccttccga gcagcagaca    780

ggagcaagac aaggagcccc aaactgtctc acagtcctca accacccagt ctgggtgacc    840

cggtcgagca tttatcagag acgtccgctg attctttgga agccatgtct gagggggatg    900

ctccaacccc tttttccaga ggcagccgga ctcgtgcgag ccttcctgtg gtgaggtcaa    960

ccaaccagac gaaagaaaga tctctggggg ttctctatct ccagtatgga gatgaaacca   1020

agcagctcag gatgccgaat gaaatcacaa gtgcagacac aatccgtgct ctcttcgtaa   1080

gtgcctttcc acagcagctc accatgaaaa tgctggaatc gcccagtgtc gccatttaca   1140

tcaaagatga aagcagaaat gtctattatg aattaaatga tgtaaggaac attcaagaca   1200

gatcactcct caaagtgtac aacaaggatc ctgcacatgc gtttaatcac acaccaaaaa   1260

ctatgaatgg agacatgagg atgcagagag aacttgttta tgcaagagga gatggccctg   1320

gggcccctcg ccccggatct actgctcatc caccccatgc gattccaaat tccccaccgt   1380

ctactccagt gccccattcc atgcccccct ccccgtccag aattccttat gggggcaccc   1440

gctccatggt tgttcctggc aatgccacca tccccaggga cagaatctcc agcctgccag   1500

tctccagacc catctctcca agcccaagcg ccattttaga aagaagagat gtcaagcctg   1560

atgaagacat gagtggcaaa aacattgcaa tgtacagaaa tgagggtttc tatgctgatc   1620

cttaccttta tcacgaggga cggatgagca tagcctcatc ccatggtgga cacccactgg   1680

atgtccccga ccacatcatt gcatatcacc gcaccgccat ccggtcagcg agtgcttatt   1740

gtaacccctc aatgcaagcg gaaatgcata tggaacaatc actgtacaga cagaaatcaa   1800

ggaaatatcc ggatagccat ttgcctacac tgggctccaa aacaccccct gcctctcctc   1860

acagagtcag tgacctgagg atgatagaca tgcacgctca ctataatgcc cacggccccc   1920

ctcacaccat gcagccagac cgggcctctc cgagccgcca ggcctttaaa aaggagccag   1980

gcaccttggt gtatatagaa aagccacgga gcgctgcagg attatccagc cttgtagacc   2040

tcggccctcc tctaatggag aagcaagttt ttgcctacag cacggcgaca atacccaaag   2100

acagagagac cag                                                      2113


<210>  6385
<211>  479
<212>  PRT
<213>  Homo sapiens

<400>  6385

Met Pro His Leu Asp Met Lys Thr His Val Cys Pro Ser Val Glu Gly 
1               5                   10                  15


Pro Lys Lys Lys Gly Gly Ile Thr Cys Phe Cys Cys Gly Gly Pro Phe 
            20                  25                  30


Arg Ala Ala Asp Arg Ser Lys Thr Arg Ser Pro Lys Leu Ser His Ser 
        35                  40                  45


Pro Gln Pro Pro Ser Leu Gly Asp Pro Val Glu His Leu Ser Glu Thr 
    50                  55                  60


Ser Ala Asp Ser Leu Glu Ala Met Ser Glu Gly Asp Ala Pro Thr Pro 
65                  70                  75                  80


Phe Ser Arg Gly Ser Arg Thr Arg Ala Ser Leu Pro Val Val Arg Ser 
                85                  90                  95


Thr Asn Gln Thr Lys Glu Arg Ser Leu Gly Val Leu Tyr Leu Gln Tyr 
            100                 105                 110


Gly Asp Glu Thr Lys Gln Leu Arg Met Pro Asn Glu Ile Thr Ser Ala 
        115                 120                 125


Asp Thr Ile Arg Ala Leu Phe Val Ser Ala Phe Pro Gln Gln Leu Thr 
    130                 135                 140


Met Lys Met Leu Glu Ser Pro Ser Val Ala Ile Tyr Ile Lys Asp Glu 
145                 150                 155                 160


Ser Arg Asn Val Tyr Tyr Glu Leu Asn Asp Val Arg Asn Ile Gln Asp 
                165                 170                 175


Arg Ser Leu Leu Lys Val Tyr Asn Lys Asp Pro Ala His Ala Phe Asn 
            180                 185                 190


His Thr Pro Lys Thr Met Asn Gly Asp Met Arg Met Gln Arg Glu Leu 
        195                 200                 205


Val Tyr Ala Arg Gly Asp Gly Pro Gly Ala Pro Arg Pro Gly Ser Thr 
    210                 215                 220


Ala His Pro Pro His Ala Ile Pro Asn Ser Pro Pro Ser Thr Pro Val 
225                 230                 235                 240


Pro His Ser Met Pro Pro Ser Pro Ser Arg Ile Pro Tyr Gly Gly Thr 
                245                 250                 255


Arg Ser Met Val Val Pro Gly Asn Ala Thr Ile Pro Arg Asp Arg Ile 
            260                 265                 270


Ser Ser Leu Pro Val Ser Arg Pro Ile Ser Pro Ser Pro Ser Ala Ile 
        275                 280                 285


Leu Glu Arg Arg Asp Val Lys Pro Asp Glu Asp Met Ser Gly Lys Asn 
    290                 295                 300


Ile Ala Met Tyr Arg Asn Glu Gly Phe Tyr Ala Asp Pro Tyr Leu Tyr 
305                 310                 315                 320


His Glu Gly Arg Met Ser Ile Ala Ser Ser His Gly Gly His Pro Leu 
                325                 330                 335


Asp Val Pro Asp His Ile Ile Ala Tyr His Arg Thr Ala Ile Arg Ser 
            340                 345                 350


Ala Ser Ala Tyr Cys Asn Pro Ser Met Gln Ala Glu Met His Met Glu 
        355                 360                 365


Gln Ser Leu Tyr Arg Gln Lys Ser Arg Lys Tyr Pro Asp Ser His Leu 
    370                 375                 380


Pro Thr Leu Gly Ser Lys Thr Pro Pro Ala Ser Pro His Arg Val Ser 
385                 390                 395                 400


Asp Leu Arg Met Ile Asp Met His Ala His Tyr Asn Ala His Gly Pro 
                405                 410                 415


Pro His Thr Met Gln Pro Asp Arg Ala Ser Pro Ser Arg Gln Ala Phe 
            420                 425                 430


Lys Lys Glu Pro Gly Thr Leu Val Tyr Ile Glu Lys Pro Arg Ser Ala 
        435                 440                 445


Ala Gly Leu Ser Ser Leu Val Asp Leu Gly Pro Pro Leu Met Glu Lys 
    450                 455                 460


Gln Val Phe Ala Tyr Ser Thr Ala Thr Ile Pro Lys Asp Arg Glu 
465                 470                 475


<210>  6386
<211>  561
<212>  DNA
<213>  Homo sapiens

<400>  6386
cgataactgc atcaccatgc atgagaatgg tgcagtaaag gctactcaac gggaagatga     60

cgaggatgaa gacctttatg atgatccact tccacttaat cttctactgg atatggttgg    120

gtcccctgac caggatctcc aggaagctgc agctggttgt atatccaata tccgcaggct    180

ggctcttgct acagagaagg caagatacac ttgaaattta aatggacatt acaagctatc    240

aaattctaca tgacacagga catgtcactc ccatggccag aaagcctaaa ttgggaaaca    300

gttgttagca aaccctttca accatctaaa tgaaaacaca caaattgaaa atgcacagaa    360

tgtttttcat ctgaaaattg catggagact tttgtttcta tttaatgttt tcgagatatg    420

acatgtgata agatggaaag ccaataaacc tgtgataagt ttctaagaat atgagaatat    480

acgtatatga tgtattttta gttcagtgat gcttttgtat ttgtggcgat tttaataaaa    540

aggatatggc cttcccaatg c                                              561


<210>  6387
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  6387

Met His Glu Asn Gly Ala Val Lys Ala Thr Gln Arg Glu Asp Asp Glu 
1               5                   10                  15


Asp Glu Asp Leu Tyr Asp Asp Pro Leu Pro Leu Asn Leu Leu Leu Asp 
            20                  25                  30


Met Val Gly Ser Pro Asp Gln Asp Leu Gln Glu Ala Ala Ala Gly Cys 
        35                  40                  45


Ile Ser Asn Ile Arg Arg Leu Ala Leu Ala Thr Glu Lys Ala Arg Tyr 
    50                  55                  60


Thr 
65


<210>  6388
<211>  3579
<212>  DNA
<213>  Homo sapiens

<400>  6388
gggcatacgg tgcaacgggt ccgcgggaat cttggatgcg cggaggtccc gagaccaggt     60

gcgtgtgcta agctcaggtc tgagcacggt ggatcccatg ggtgtggctc tgaggaaatt    120

gacgcagtgg actgctgccg gacatggaac tggaatcctc gaaatcaccc ctctaaatga    180

agcgatattg aaagaaatta ttgtgtttgt ggagagtttt atctataaac atcctcaaga    240

ggcaaaattt gtttttgtgg aaccacttga atggaacaca agtttggcgc cctcagcatt    300

tgaatcaggt tatgttgtca gtgaaacaac agtcaaatca gaagaagttg ataaaaatgg    360

acagcctttg ctatttctct ctgtaccaca aattaaaatt aggagctttg ggcagctgtc    420

acgcttgtta cttattgcca aaactgggaa gttgaaggaa gcccaagcat gtgttgaagc    480

taacagagac cccatagtaa aaatcctggg ctctgattat aatacaatga aagaaaactc    540

aattgcatta aatattcttg gcaaaattac cagagatgat gatcctgaaa gtgaaattaa    600

gatgaagatt gctatgctgc ttaagcaatt ggatctgcac ctcctcaatc attctctaaa    660

acatatttca ttagaaataa gtttaagtcc catgacggtg aagaaggata tagaactgct    720

caaacgtttc tcaggaaaag gaaaccaaac agtcttggaa tctattgaat atacctcaga    780

ttatgaattt tcaaatggat gtcgagcccc accgtggaga caaattcgtg gggaaatttg    840

ttatgtgctg gtgaaacctc acgatggtga gactctgtgc attacttgca gtgcaggagg    900

agtattttta aatggtggca aaacagatga tgaaggggac gttaattatg agagaaaagg    960

ttcaatttat aaaaaccttg tcacattttt aagagaaaaa tcaccaaaat tttcagaaaa   1020

tatgtctaaa ttgggaatta gcttcagtga agaccagcaa aaggaaaagg atcagcttgg   1080

caaagccccc aagaaggaag aagcagctgc cctccgcaaa gacatttctg gttcagacaa   1140

aaggtcactg gagaagaacc aaattaattt ttggaggaat caaatgacca agagatggga   1200

accaagctta aactggaaga ccactgttaa ttacaaaggc aaaggctcag caaaagaaat   1260

ccaagaggac aaacacacag gaaaacttga aaaaccaaga ccatctgttt cacacggaag   1320

agcacaatta cttcggaaga gtgctgaaaa gattgaggaa actgttagcg atagctcctc   1380

agaaagtgag gaagatgaag aaccacctga ccatcgtcag gaagcaagtg cagatttgcc   1440

atcagaatat tggcaaattc agaagctggt gaaatattta aagggaggaa atcaaacagc   1500

tacagtgatt gcgttgtgtt caatgaggga tttcagctta gctcaagaaa cctgccagtt   1560

ggccatcaga gatgttggag gcctggaagt gctgataaat ttgcttgaaa ccgatgaagt   1620

caaatgtaag attggttcat taaaaatact gaaggaaatc agtcataatc ctcaaatcag   1680

acagaatatt gttgaccttg ggggcttacc aattatggtg aatatacttg attctccaca   1740

caagagtcta aaatgtttgg cagccgagac tatcgcgaat gttgccaagt ttaaaagagc   1800

acggcgggtg gtgaggcagc acgggggtat caccaaactg gttgctctac tagactgtgc   1860

acatgattcc acaaaacctg cccaatcgag tctgtatgag gccagagacg tggaagtggc   1920

tcgctgtggg gcactggccc tgtggagctg cagtaagagt catacgaata aagaagccat   1980

ccgcaaagct gggggcattc ctctgttggc tcggctgctg aagacttctc atgaaaacat   2040

gctaattcca gtggtgggga cattgcaaga gtgtgcatca gaggaaaact accgggctgc   2100

aatcaaagca gaaaggatca ttgaaaacct tgtcaagaac ctaaatagtg agaatgagca   2160

gctgcaggag cactgcgcca tggccattta ccagtgtgct gaagataagg aaacccggga   2220

cctcgttagg ctgcacggag gacttaagcc cttggccagt ctactcaata acactgacaa   2280

taaagagcgg ttagctgctg tcacaggggc tatatggaaa tgttccatca gcaaagagaa   2340

tgttaccaag tttcgggaat acaaagccat tgaaaccttg gtgggacttc taacagatca   2400

gcctgaagaa gtacttgtga atgtggttgg ggccttggga gaatgctgcc aagaacgtga   2460

aaaccgagtc attgtccgga aatgtggtgg cattcaacca cttgtgaacc tccttgttgg   2520

aataaaccaa gctcttcttg tgaatgttac aaaagcagtt ggtgcttgtg cagtagaacc   2580

tgaaagtatg atgataattg atcgcttaga tggagttcgt ttgttgtggt ccctgctgaa   2640

aaatcctcac ccagacgtga aggccagcgc agcatgggca ctctgtccat gcatcaaaaa   2700

tgcaaaggat gctggggaaa tggttcgttc ctttgttggt ggtttggaac ttattgtcaa   2760

tttactgaaa tcagataaca aagaagttct ggcaagtgta tgtgctgcca ttaccaacat   2820

agcaaaagat caagaaaatt tagctgttat cacagatcat ggagttgttc ctttattgtc   2880

caaactggca aatacaaata acaataaatt gagacatcat ctagcagaag ctatttcacg   2940

ttgctgtatg tggggcagga atagagtggc cttcggtgag cacaaagcag tggctccact   3000

agtgcgttat ctgaaatcaa atgacaccaa cgtgcatcgg gcgacagctc aggccttgta   3060

ccaactctca gaagacgccg ataactgcat caccatgcat gagaatggtg cagtaaagct   3120

tctactggat atggttgggt cccctgacca ggatctccag gaagctgcag ctggttgtat   3180

atccaatatc cgcaggctgg ctcttgctac agagaaggca agatacactt gaaatttaaa   3240

tggacattac aagctatcaa attctacatg acacaggaca tgtcactccc atggccagaa   3300

agcctaaatt gggaaacagt tgttagcaaa ccctttcaac catctaaatg aaaacacaca   3360

aattgaaaat gcacagaatg tttttcatct gaaaattgca tggagacttt tgtttctatt   3420

taatgttttc gagatatgac atgtgataag atggaaagcc aataaacctg tgataagttt   3480

ctaagaatat gagaatatac gtatatgatg tatttttagt tcagtgatgc ttttgtattt   3540

gtggcgattt taataaaaag gatatggcct tcccaatgc                          3579


<210>  6389
<211>  1044
<212>  PRT
<213>  Homo sapiens

<400>  6389

Met Gly Val Ala Leu Arg Lys Leu Thr Gln Trp Thr Ala Ala Gly His 
1               5                   10                  15


Gly Thr Gly Ile Leu Glu Ile Thr Pro Leu Asn Glu Ala Ile Leu Lys 
            20                  25                  30


Glu Ile Ile Val Phe Val Glu Ser Phe Ile Tyr Lys His Pro Gln Glu 
        35                  40                  45


Ala Lys Phe Val Phe Val Glu Pro Leu Glu Trp Asn Thr Ser Leu Ala 
    50                  55                  60


Pro Ser Ala Phe Glu Ser Gly Tyr Val Val Ser Glu Thr Thr Val Lys 
65                  70                  75                  80


Ser Glu Glu Val Asp Lys Asn Gly Gln Pro Leu Leu Phe Leu Ser Val 
                85                  90                  95


Pro Gln Ile Lys Ile Arg Ser Phe Gly Gln Leu Ser Arg Leu Leu Leu 
            100                 105                 110


Ile Ala Lys Thr Gly Lys Leu Lys Glu Ala Gln Ala Cys Val Glu Ala 
        115                 120                 125


Asn Arg Asp Pro Ile Val Lys Ile Leu Gly Ser Asp Tyr Asn Thr Met 
    130                 135                 140


Lys Glu Asn Ser Ile Ala Leu Asn Ile Leu Gly Lys Ile Thr Arg Asp 
145                 150                 155                 160


Asp Asp Pro Glu Ser Glu Ile Lys Met Lys Ile Ala Met Leu Leu Lys 
                165                 170                 175


Gln Leu Asp Leu His Leu Leu Asn His Ser Leu Lys His Ile Ser Leu 
            180                 185                 190


Glu Ile Ser Leu Ser Pro Met Thr Val Lys Lys Asp Ile Glu Leu Leu 
        195                 200                 205


Lys Arg Phe Ser Gly Lys Gly Asn Gln Thr Val Leu Glu Ser Ile Glu 
    210                 215                 220


Tyr Thr Ser Asp Tyr Glu Phe Ser Asn Gly Cys Arg Ala Pro Pro Trp 
225                 230                 235                 240


Arg Gln Ile Arg Gly Glu Ile Cys Tyr Val Leu Val Lys Pro His Asp 
                245                 250                 255


Gly Glu Thr Leu Cys Ile Thr Cys Ser Ala Gly Gly Val Phe Leu Asn 
            260                 265                 270


Gly Gly Lys Thr Asp Asp Glu Gly Asp Val Asn Tyr Glu Arg Lys Gly 
        275                 280                 285


Ser Ile Tyr Lys Asn Leu Val Thr Phe Leu Arg Glu Lys Ser Pro Lys 
    290                 295                 300


Phe Ser Glu Asn Met Ser Lys Leu Gly Ile Ser Phe Ser Glu Asp Gln 
305                 310                 315                 320


Gln Lys Glu Lys Asp Gln Leu Gly Lys Ala Pro Lys Lys Glu Glu Ala 
                325                 330                 335


Ala Ala Leu Arg Lys Asp Ile Ser Gly Ser Asp Lys Arg Ser Leu Glu 
            340                 345                 350


Lys Asn Gln Ile Asn Phe Trp Arg Asn Gln Met Thr Lys Arg Trp Glu 
        355                 360                 365


Pro Ser Leu Asn Trp Lys Thr Thr Val Asn Tyr Lys Gly Lys Gly Ser 
    370                 375                 380


Ala Lys Glu Ile Gln Glu Asp Lys His Thr Gly Lys Leu Glu Lys Pro 
385                 390                 395                 400


Arg Pro Ser Val Ser His Gly Arg Ala Gln Leu Leu Arg Lys Ser Ala 
                405                 410                 415


Glu Lys Ile Glu Glu Thr Val Ser Asp Ser Ser Ser Glu Ser Glu Glu 
            420                 425                 430


Asp Glu Glu Pro Pro Asp His Arg Gln Glu Ala Ser Ala Asp Leu Pro 
        435                 440                 445


Ser Glu Tyr Trp Gln Ile Gln Lys Leu Val Lys Tyr Leu Lys Gly Gly 
    450                 455                 460


Asn Gln Thr Ala Thr Val Ile Ala Leu Cys Ser Met Arg Asp Phe Ser 
465                 470                 475                 480


Leu Ala Gln Glu Thr Cys Gln Leu Ala Ile Arg Asp Val Gly Gly Leu 
                485                 490                 495


Glu Val Leu Ile Asn Leu Leu Glu Thr Asp Glu Val Lys Cys Lys Ile 
            500                 505                 510


Gly Ser Leu Lys Ile Leu Lys Glu Ile Ser His Asn Pro Gln Ile Arg 
        515                 520                 525


Gln Asn Ile Val Asp Leu Gly Gly Leu Pro Ile Met Val Asn Ile Leu 
    530                 535                 540


Asp Ser Pro His Lys Ser Leu Lys Cys Leu Ala Ala Glu Thr Ile Ala 
545                 550                 555                 560


Asn Val Ala Lys Phe Lys Arg Ala Arg Arg Val Val Arg Gln His Gly 
                565                 570                 575


Gly Ile Thr Lys Leu Val Ala Leu Leu Asp Cys Ala His Asp Ser Thr 
            580                 585                 590


Lys Pro Ala Gln Ser Ser Leu Tyr Glu Ala Arg Asp Val Glu Val Ala 
        595                 600                 605


Arg Cys Gly Ala Leu Ala Leu Trp Ser Cys Ser Lys Ser His Thr Asn 
    610                 615                 620


Lys Glu Ala Ile Arg Lys Ala Gly Gly Ile Pro Leu Leu Ala Arg Leu 
625                 630                 635                 640


Leu Lys Thr Ser His Glu Asn Met Leu Ile Pro Val Val Gly Thr Leu 
                645                 650                 655


Gln Glu Cys Ala Ser Glu Glu Asn Tyr Arg Ala Ala Ile Lys Ala Glu 
            660                 665                 670


Arg Ile Ile Glu Asn Leu Val Lys Asn Leu Asn Ser Glu Asn Glu Gln 
        675                 680                 685


Leu Gln Glu His Cys Ala Met Ala Ile Tyr Gln Cys Ala Glu Asp Lys 
    690                 695                 700


Glu Thr Arg Asp Leu Val Arg Leu His Gly Gly Leu Lys Pro Leu Ala 
705                 710                 715                 720


Ser Leu Leu Asn Asn Thr Asp Asn Lys Glu Arg Leu Ala Ala Val Thr 
                725                 730                 735


Gly Ala Ile Trp Lys Cys Ser Ile Ser Lys Glu Asn Val Thr Lys Phe 
            740                 745                 750


Arg Glu Tyr Lys Ala Ile Glu Thr Leu Val Gly Leu Leu Thr Asp Gln 
        755                 760                 765


Pro Glu Glu Val Leu Val Asn Val Val Gly Ala Leu Gly Glu Cys Cys 
    770                 775                 780


Gln Glu Arg Glu Asn Arg Val Ile Val Arg Lys Cys Gly Gly Ile Gln 
785                 790                 795                 800


Pro Leu Val Asn Leu Leu Val Gly Ile Asn Gln Ala Leu Leu Val Asn 
                805                 810                 815


Val Thr Lys Ala Val Gly Ala Cys Ala Val Glu Pro Glu Ser Met Met 
            820                 825                 830


Ile Ile Asp Arg Leu Asp Gly Val Arg Leu Leu Trp Ser Leu Leu Lys 
        835                 840                 845


Asn Pro His Pro Asp Val Lys Ala Ser Ala Ala Trp Ala Leu Cys Pro 
    850                 855                 860


Cys Ile Lys Asn Ala Lys Asp Ala Gly Glu Met Val Arg Ser Phe Val 
865                 870                 875                 880


Gly Gly Leu Glu Leu Ile Val Asn Leu Leu Lys Ser Asp Asn Lys Glu 
                885                 890                 895


Val Leu Ala Ser Val Cys Ala Ala Ile Thr Asn Ile Ala Lys Asp Gln 
            900                 905                 910


Glu Asn Leu Ala Val Ile Thr Asp His Gly Val Val Pro Leu Leu Ser 
        915                 920                 925


Lys Leu Ala Asn Thr Asn Asn Asn Lys Leu Arg His His Leu Ala Glu 
    930                 935                 940


Ala Ile Ser Arg Cys Cys Met Trp Gly Arg Asn Arg Val Ala Phe Gly 
945                 950                 955                 960


Glu His Lys Ala Val Ala Pro Leu Val Arg Tyr Leu Lys Ser Asn Asp 
                965                 970                 975


Thr Asn Val His Arg Ala Thr Ala Gln Ala Leu Tyr Gln Leu Ser Glu 
            980                 985                 990


Asp Ala Asp Asn Cys Ile Thr Met His Glu Asn Gly Ala Val Lys Leu 
        995                 1000                1005


Leu Leu Asp Met Val Gly Ser Pro Asp Gln Asp Leu Gln Glu Ala Ala 
    1010                1015                1020


Ala Gly Cys Ile Ser Asn Ile Arg Arg Leu Ala Leu Ala Thr Glu Lys 
1025                1030                1035                1040


Ala Arg Tyr Thr 



<210>  6390
<211>  545
<212>  DNA
<213>  Homo sapiens

<400>  6390
acagaatatt gttgaccttg ggggcttacc aattatggtg aatatacttg attctccaca     60

caagagtcta aaatgtttgg cagccgagac tatcgcgaat gttgctctac tagactgtgc    120

acatgattcc acaaaacctg cccaatcgag tctgtatgag gccagagacg tggaagtggc    180

tcgctgtggg gcactggccc tgtggagctg cagtaagagt catacgaata aagaagccat    240

ccgcaaagct gggggcattc ctctgttggc tcggctgctg aagacttctc atgaaaacat    300

gctaattcca gtggtgggga cattgcaaga gtgtgcatca gaggaaaact accgggctgc    360

aatcaaagca gaaaggatca ttgaaaacct tgtcaagaac ctaaatagtg agaatgagca    420

gctgcaagga tgctggggaa atggttcgtt cctttgttgg tggtttggaa cttattgtca    480

atttactgaa atcagataac aaagaagttc tggcaagtgt atgtgctgcc attaccaaca    540

tagca                                                                545


<210>  6391
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  6391

Met Val Asn Ile Leu Asp Ser Pro His Lys Ser Leu Lys Cys Leu Ala 
1               5                   10                  15


Ala Glu Thr Ile Ala Asn Val Ala Leu Leu Asp Cys Ala His Asp Ser 
            20                  25                  30


Thr Lys Pro Ala Gln Ser Ser Leu Tyr Glu Ala Arg Asp Val Glu Val 
        35                  40                  45


Ala Arg Cys Gly Ala Leu Ala Leu Trp Ser Cys Ser Lys Ser His Thr 
    50                  55                  60


Asn Lys Glu Ala Ile Arg Lys Ala Gly Gly Ile Pro Leu Leu Ala Arg 
65                  70                  75                  80


Leu Leu Lys Thr Ser His Glu Asn Met Leu Ile Pro Val Val Gly Thr 
                85                  90                  95


Leu Gln Glu Cys Ala Ser Glu Glu Asn Tyr Arg Ala Ala Ile Lys Ala 
            100                 105                 110


Glu Arg Ile Ile Glu Asn Leu Val Lys Asn Leu Asn Ser Glu Asn Glu 
        115                 120                 125


Gln Leu Gln Gly Cys Trp Gly Asn Gly Ser Phe Leu Cys Trp Trp Phe 
    130                 135                 140


Gly Thr Tyr Cys Gln Phe Thr Glu Ile Arg 
145                 150


<210>  6392
<211>  5063
<212>  DNA
<213>  Homo sapiens

<400>  6392
aatggaacta acaggaacca cctgtgcact tccttttaca ggaatgttca taaacagcag     60

gttctcctag gctttgaaca aaatttagct tctccaaggc caaaagcctc attgtgaaga    120

gaaagaaaga aacggcttac aaaatataca gatcttggta gacaacgtgg ctgcaggctg    180

ttgaattgga attccctgtg gctgtccgaa ggcagggtgt ccggagagcg gtgggctgac    240

ctgttcctac accttgcatc atgccagctt tgtcaacggg atctgggagt gacactggtc    300

tgtatgagct gttggctgct ctgccagccc agctgcagcc acatgtggat agccaggaag    360

acctgacctt cctctgggat atgtttggtg aaaaaagcct gcattcattg gtaaagattc    420

atgaaaaact acactactat gagaagcaga gtccggtgcc cattctccat ggtgcggcgg    480

ccttggccga tgatctggcc gaagagcttc agaacaagcc attaaacagt gagatcagag    540

agctgttgaa actactgtca aaacccaatg tgaaggcttt gctctctgta catgatactg    600

tggctcagaa gaattacgac ccagtgttgc ctcctatgcc tgaagatatt gacgatgagg    660

aagactcagt aaaaataatc cgtctggtca aaaatagaga accactggga gctaccatta    720

agaaggatga acagaccggg gcgatcattg tggccagaat catgagagga ggagctgcag    780

atagaagtgg tcttattcat gttggtgatg aacttaggga agtcaacggg ataccagtgg    840

aggataaaag gcctgaggaa ataatacaga ttttggctca gtctcaggga gcaattacat    900

ttaagattat acccggcagc aaagaggaga caccatcaaa agaaggcaag atgtttatca    960

aagccctctt tgactataat cctaatgagg ataaggcaat tccatgtaag gaagctgggc   1020

tttctttcaa aaagggagat attcttcaga ttatgagcca agatgatgca acttggtggc   1080

aagcgaaaca cgaagctgat gccaacccca gggcaggctt gatcccctca aagcatttcc   1140

aggaaaggag attggctttg agacgaccag aaatattggt tcagcccctg aaagtttcca   1200

acaggaaatc atctggtttt agaaaaagtt ttcgtcttag tagaaaagat aagaaaacaa   1260

ataaatccat gtatgaatgc aagaagagtg atcagtacga cacagctgac gtacccacat   1320

acgaagaagt gacaccgtat cggcgacaaa ctaatgaaaa atacagactc gttgtcttgg   1380

ttggtcccgt gggagtaggg ctgaatgaac tgaaacgaaa gctgctgatc agtgacaccc   1440

agcactatgg cgtgacagtg ccccatacca ccagagcaag aagaagccag gagagtgatg   1500

gtgttgaata cattttcatt tccaagcatt tgtttgagac agatgtacaa aataacaagt   1560

ttattgaata tggagaatat aaaaacaact actacggcac aagtatagac tcagttcggt   1620

ctgtccttgc taaaaacaaa gtttgtttgt tggatgttca gcctcataca gtgaagcatt   1680

taaggacact agaatttaag ccctatgtga tatttataaa gcctccatca atagagcgtt   1740

tgagagaaac aagaaaaaat gcaaagatta tttcaagcag agatgaccaa ggtgctgcaa   1800

aacccttcac agaagaagat tttcaagaaa tgattaaatc tgcacagata atggaaagtc   1860

aatatggtca tctttttgac aaaattataa taaatgatga cctcactgtg gcattcaatg   1920

agctcaaaac aacttttgac aaattagaga cagagaccca ttgggtgcca gtgagctggt   1980

tacattcata actaagagaa atttccataa ttgtcttttt ctatagagtg catgatgaaa   2040

tcaattacag ttttggtagt agggttttta aatctatatc actgtcatag atgtacaatc   2100

ttggttcaag ttgaatgctg gttttgtttg tatcttttta cagccttatt tcaaacgcca   2160

tgtgttagta taagatccga aatcaaaata tgcacagtac tgtattctaa gcaaaacctc   2220

aaaccttctc gttgtcttca ataccgctct atctccaaga tgaggctgaa attttcagag   2280

agacttagct agaggcttag tatgtatggg agttcagcgc ttctgctggt ctcaggtgtg   2340

gctgctgctg tcgagtttga atgttagctg ttgaaggtat caattcagca gccatgagca   2400

gctccagaca gacaggtgag ctctgctgtt tctgggtgga tcatcacaga tttagccggg   2460

caggcagtaa ggtgtcctct tactattcaa aaagtgtaga ctttcttaca tattcgcaat   2520

acgttcacag tgtgtgcatt ttaaaataat tcttaaagga gtaactgaaa ttttaccttg   2580

agtgaatggc cttcataata tagcttgaga agtccttttg agtacctgtc agtgactcaa   2640

caacatttaa taagggaaag tagactttta acagttatta tatatgtaac gaaaagcctt   2700

tcctttggga ttaatataag taagaatggt agccttgtgg caagaaatga ttacaaagga   2760

tatttttatt tgtaattcct cagaagacaa tttatgaagt cacccaaaat gttattttag   2820

ctggttttgg atttttccaa taaattagaa gaaggatttc tattctaaaa catgtaaaac   2880

ctgttttaca tattactgat acaattaaag attatttttc atctatgtgc aatagatcac   2940

ccctctttaa attgctctaa gatttatttt agaaaacttt tcatgtgatg ttatttcttt   3000

gtcatcaaaa tgcttgttaa cactgtccag acaccatcct aaccttgcca ttgttaaaga   3060

agtttaggaa agactcttat attgtaaata tttagatggg ttctctcact tttctttgat   3120

actactgatt ttcagcaagt gaattatata attcaaaatg ctagaaatgt ctatccgttc   3180

tataagagag catatcctgc cgttcttgca tgcagtgaag ccctgcccgt cgaaaatcat   3240

tgcatctgtg actttcaaag tggaaaaaaa aatgttattt ttttgttgat ttgtaaagag   3300

agtttaaatg tcatgtgaaa aaaaatagaa tgtagtaaaa ttctatatat ttatgaaata   3360

ttttaaaggc atattttttt aaatatcaaa cggggctatt cataaaataa actgattgta   3420

tgtcaagatg tcctaattta aaagagtagt tttataaatc atggtcaaca ttccatgtaa   3480

atatttgagc tttacaaaga tagatccaag tgtgcgatct gtgcactgca catttgatag   3540

cattattcac tggttttcct tcatacttgt caagttcata ttagaagcag agacaaaaac   3600

cactccaatg gccttgacac atagtcacac caaaatagat aatcagacta agtattatat   3660

aacaacgtga tccagacagt gagttctaag tgtattaatt aaatagcaaa aaattttgtt   3720

tttaaaaaat gaaagaggga gggttgccaa cctgaagtct taagtagatt gtttgggtag   3780

catatttcct tctttgaaca ttgtctgaaa ttttctataa atcaagactt cttgtacaaa   3840

gaatgatggg acatatgtaa taattcaggc aatcacctga gtaatttagg cagtccaaat   3900

tctttaccct gaaataccca cattttaaaa aaattgcaga taattgcttc agttatttac   3960

tttggggaca gagatatagt gtaaagtggg agaaactgag tccttttttg gtggtggtaa   4020

taataagatg ttataaaaat ataacatttt aaaaaagaaa ggtccagacc ttaagcgcag   4080

agctagaaca atatttttta aataatgggg ggaaaagggg gcactttggt aattttagaa   4140

atcaggtagt atactttttt tttttttttt gagacagggt cttgccatgt tgctcaggct   4200

ggtcttgaac tcctgggctc aagcaatcct cctgccttgg cctcccaaag tgctgggatt   4260

acaggcatga tccaccgtgc ccagccggta gacgtggtct taaaaacagt gtttacatgg   4320

ccatcttgat gcttagaaag ataattgatt aaaatttaat aaggcagggc caactccgag   4380

agttcattga caacggcagc aaaaaggccc tgaattctgt actttcttcc cccagcctcc   4440

ttctccagca aggagaatag cactcctccc tccagaagcc agctccctaa gttggagcca   4500

ctatgtaaga gaagaggaac gttcactttt taaaattcat atatttaaaa atcaagacca   4560

aaaagtaaat tctgtactcc tattattgac tgtagtcaat caaacataaa aaggtgaaag   4620

taaaatttaa ttttttaccc ttattttact gaccaatatg gaagttcttg gtatctttaa   4680

ggctgacctt cctggtattg tgtaatgatt gaatgtatct aaactgtaat aatttgaaac   4740

tgacaaacat aaccttctca gacttacaaa actatgttct ttctaaagat acagattttt   4800

attattttat tttgactagg aaggatttat aaataaatgt aatgaaaaat ctttgatctt   4860

aataaagtac cttcaaacag tgtgtgtact tacttgaaaa ttgtttttgc acttggatat   4920

tctattttat tatactacta ttgtgatcta ttccattata ctatttccca tggtagaaca   4980

aattatattt tctactgtga tatgaagtga tgtaattgaa cttgccatgt ctaaaattaa   5040

atttcatatt tttttcaatc aaa                                           5063


<210>  6393
<211>  576
<212>  PRT
<213>  Homo sapiens

<400>  6393

Met Pro Ala Leu Ser Thr Gly Ser Gly Ser Asp Thr Gly Leu Tyr Glu 
1               5                   10                  15


Leu Leu Ala Ala Leu Pro Ala Gln Leu Gln Pro His Val Asp Ser Gln 
            20                  25                  30


Glu Asp Leu Thr Phe Leu Trp Asp Met Phe Gly Glu Lys Ser Leu His 
        35                  40                  45


Ser Leu Val Lys Ile His Glu Lys Leu His Tyr Tyr Glu Lys Gln Ser 
    50                  55                  60


Pro Val Pro Ile Leu His Gly Ala Ala Ala Leu Ala Asp Asp Leu Ala 
65                  70                  75                  80


Glu Glu Leu Gln Asn Lys Pro Leu Asn Ser Glu Ile Arg Glu Leu Leu 
                85                  90                  95


Lys Leu Leu Ser Lys Pro Asn Val Lys Ala Leu Leu Ser Val His Asp 
            100                 105                 110


Thr Val Ala Gln Lys Asn Tyr Asp Pro Val Leu Pro Pro Met Pro Glu 
        115                 120                 125


Asp Ile Asp Asp Glu Glu Asp Ser Val Lys Ile Ile Arg Leu Val Lys 
    130                 135                 140


Asn Arg Glu Pro Leu Gly Ala Thr Ile Lys Lys Asp Glu Gln Thr Gly 
145                 150                 155                 160


Ala Ile Ile Val Ala Arg Ile Met Arg Gly Gly Ala Ala Asp Arg Ser 
                165                 170                 175


Gly Leu Ile His Val Gly Asp Glu Leu Arg Glu Val Asn Gly Ile Pro 
            180                 185                 190


Val Glu Asp Lys Arg Pro Glu Glu Ile Ile Gln Ile Leu Ala Gln Ser 
        195                 200                 205


Gln Gly Ala Ile Thr Phe Lys Ile Ile Pro Gly Ser Lys Glu Glu Thr 
    210                 215                 220


Pro Ser Lys Glu Gly Lys Met Phe Ile Lys Ala Leu Phe Asp Tyr Asn 
225                 230                 235                 240


Pro Asn Glu Asp Lys Ala Ile Pro Cys Lys Glu Ala Gly Leu Ser Phe 
                245                 250                 255


Lys Lys Gly Asp Ile Leu Gln Ile Met Ser Gln Asp Asp Ala Thr Trp 
            260                 265                 270


Trp Gln Ala Lys His Glu Ala Asp Ala Asn Pro Arg Ala Gly Leu Ile 
        275                 280                 285


Pro Ser Lys His Phe Gln Glu Arg Arg Leu Ala Leu Arg Arg Pro Glu 
    290                 295                 300


Ile Leu Val Gln Pro Leu Lys Val Ser Asn Arg Lys Ser Ser Gly Phe 
305                 310                 315                 320


Arg Lys Ser Phe Arg Leu Ser Arg Lys Asp Lys Lys Thr Asn Lys Ser 
                325                 330                 335


Met Tyr Glu Cys Lys Lys Ser Asp Gln Tyr Asp Thr Ala Asp Val Pro 
            340                 345                 350


Thr Tyr Glu Glu Val Thr Pro Tyr Arg Arg Gln Thr Asn Glu Lys Tyr 
        355                 360                 365


Arg Leu Val Val Leu Val Gly Pro Val Gly Val Gly Leu Asn Glu Leu 
    370                 375                 380


Lys Arg Lys Leu Leu Ile Ser Asp Thr Gln His Tyr Gly Val Thr Val 
385                 390                 395                 400


Pro His Thr Thr Arg Ala Arg Arg Ser Gln Glu Ser Asp Gly Val Glu 
                405                 410                 415


Tyr Ile Phe Ile Ser Lys His Leu Phe Glu Thr Asp Val Gln Asn Asn 
            420                 425                 430


Lys Phe Ile Glu Tyr Gly Glu Tyr Lys Asn Asn Tyr Tyr Gly Thr Ser 
        435                 440                 445


Ile Asp Ser Val Arg Ser Val Leu Ala Lys Asn Lys Val Cys Leu Leu 
    450                 455                 460


Asp Val Gln Pro His Thr Val Lys His Leu Arg Thr Leu Glu Phe Lys 
465                 470                 475                 480


Pro Tyr Val Ile Phe Ile Lys Pro Pro Ser Ile Glu Arg Leu Arg Glu 
                485                 490                 495


Thr Arg Lys Asn Ala Lys Ile Ile Ser Ser Arg Asp Asp Gln Gly Ala 
            500                 505                 510


Ala Lys Pro Phe Thr Glu Glu Asp Phe Gln Glu Met Ile Lys Ser Ala 
        515                 520                 525


Gln Ile Met Glu Ser Gln Tyr Gly His Leu Phe Asp Lys Ile Ile Ile 
    530                 535                 540


Asn Asp Asp Leu Thr Val Ala Phe Asn Glu Leu Lys Thr Thr Phe Asp 
545                 550                 555                 560


Lys Leu Glu Thr Glu Thr His Trp Val Pro Val Ser Trp Leu His Ser 
                565                 570                 575


<210>  6394
<211>  4882
<212>  DNA
<213>  Homo sapiens

<400>  6394
aatggaacta acaggaacca cctgtgcact tccttttaca ggaatgttca taaacagcag     60

gttctcctag gctttgaaca aaatttagct tctccaaggc caaaagcctc attgtgaaga    120

gaaagaaaga aacggcttac aaaatataca gatcttggta gacaacgtgg ctgcaggctg    180

ttgaattgga attccctgtg gctgtccgaa ggcagggtgt ccggagagcg gtgggctgac    240

ctgttcctac accttgcatc atgccagctt tgtcaacggg atctgggagt gacactggtc    300

tgtatgagct gttggctgct ctgccagccc agctgcagcc acatgtggat agccaggaag    360

acctgacctt cctctgggat atgtttggtg aaaaaagcct gcattcattg gtaaagattc    420

atgaaaaact acactactat gagaagcaga gtccggtgcc cattctccat ggtgcggcgg    480

ccttggccga tgatctggcc gaagagcttc agaacaagcc attaaacagt gagatcagag    540

agctgttgaa actactgtca aaacccaatg tgaaggcttt gctctctgta catgatactg    600

tggctcagaa gaattacgac ccagtgttgc ctcctatgcc tgaagatatt gacgatgagg    660

aagactcagt aaaaataatc cgtctggtca aaaatagaga accactggga gctaccatta    720

agaaggatga acagaccggg gcgatcattg tggccagaat catgagagga ggagctgcag    780

atagaagtgg tcttattcat gttggtgatg aacttaggga agtcaacggg ataccagtgg    840

aggataaaag gcctgaggaa ataatacaga ttttggctca gtctcaggga gcaattacat    900

ttaagattat acccggcagc aaagaggaga caccatcaaa agaaggcaag atgtttatca    960

aagccctctt tgactataat cctaatgagg ataaggcaat tccatgtaag gaagctgggc   1020

tttctttcaa aaagggagat attcttcaga ttatgagcca agatgatgca acttggtggc   1080

aagcgaaaca cgaagctgat gccaacccca gggcaggctt gatcccctca aagcatttcc   1140

aggaaaggag attggctttg agacgaccag aaatattggt tcagcccctg aaagtttcca   1200

acaggaaatc atctggtttt agaaaaagtt ttcgtcttag tagaaaagat aagaaaacaa   1260

ataaatccat gtatgaatgc aagaagagtg atcagtacga cacagctgac gtacccacat   1320

acgaagaagt gacaccgtat cggcgacaaa ctaatgaaaa atacagactc gttgtcttgg   1380

ttggtcccgt gggagtaggg ctgaatgaac tgaaacgaaa gctgctgatc agtgacaccc   1440

agcactatgg cgtgacagtg ccccatacca ccagagcaag aagaagccag gagagtgatg   1500

gtgttgaata cattttcatt tccaagcatt tgtttgagac agatgtacaa aataacaagt   1560

ttattgaata tggagaatat aaaaacaact actacggcac aagtatagac tcagttcggt   1620

ctgtccttgc taaaaacaaa gtttgtttgt tggatgttca gcctcataca gtgaagcatt   1680

taaggacact agaatttaag ccctatgtga tatttataaa gcctccatca atagagcgtt   1740

tgagagaaac aagaaaaaat gcaaagatta tttcaagcag agatgaccaa ggtgctgcaa   1800

aacccttcac agaagaagat tttcaagaaa tgattaaatc tgcacagata atggaaagtc   1860

aatatggtca tctttttgac aaaattataa taaatgatga cctcactgtg gcattcaatg   1920

agctcaaaac aacttttgac aaattagaga cagagaccca ttgggtgcca gtgagctggt   1980

tacattcata actaagagaa atttccataa ttgtcttttt ctatagagtg catgatgaaa   2040

tcaattacag ttttggtagt agggttttta aatctatatc actgtcatag atgtacaatc   2100

ttggttcaag ttgaatgctg gttttgtttg tatcttttta cagccttatt tcaaacgcca   2160

tgtgttagta taagatccga aatcaaaata tgcacagtac tgtattctaa gcaaaacctc   2220

aaaccttctc gttgtcttca ataccgctct atctccaaga tgaggctgaa attttcagag   2280

agacttagct agaggcttag tatgtatggg agttcagcgc ttctgctggt ctcaggtgtg   2340

gctgctgctg tcgagtttga atgttagctg ttgaaggtat caattcagca gccatgagca   2400

gctccagaca gacaggtgag ctctgctgtt tctgggtgga tcatcacaga tttagccggg   2460

caggcagtaa ggtgtcctct tactattcaa aaagtgtaga ctttcttaca tattcgcaat   2520

acgttcacag tgtgtgcatt ttaaaataat tcttaaagga gtaactgaaa ttttaccttg   2580

agtgaatggc cttcataata tagcttgaga agtccttttg agtacctgtc agtgactcaa   2640

caacatttaa taagggaaag tagactttta acagttatta tatatgtaac gaaaagcctt   2700

tcctttggga ttaatataag taagaatggt agccttgtgg caagaaatga ttacaaagga   2760

tatttttatt tgtaattcct cagaagacaa tttatgaagt cacccaaaat gttattttag   2820

ctggttttgg atttttccaa taaattagaa gaaggatttc tattctaaaa catgtaaaac   2880

ctgttttaca tattactgat acaattaaag attatttttc atctatgtgc aatagatcac   2940

ccctctttaa attgctctaa gatttatttt agaaaacttt tcatgtgatg ttatttcttt   3000

gtcatcaaaa tgcttgttaa cactgtccag acaccatcct aaccttgcca ttgttaaaga   3060

agtttaggaa agactcttat attgtaaata tttagatggg ttctctcact tttctttgat   3120

actactgatt ttcagcaagt gaattatata attcaaaatg ctagaaatgt ctatccgttc   3180

tataagagag catatcctgc cgttcttgca tgcagtgaag ccctgcccgt cgaaaatcat   3240

tgcatctgtg actttcaaag tggaaaaaaa aatgttattt ttttgttgat ttgtaaagag   3300

agtttaaatg tcatgtgaaa aaaaatagaa tgtagtaaaa ttctatatat ttatgaaata   3360

ttttaaaggc atattttttt aaatatcaaa cggggctatt cataaaataa actgattgta   3420

tgtcaagatg tcctaattta aaagagtagt tttataaatc atggtcaaca ttccatgtaa   3480

atatttgagc tttacaaaga tagatccaag tgtgcgatct gtgcactgca catttgatag   3540

cattattcac tggttttcct tcatacttgt caagttcata ttagaagcag agacaaaaac   3600

cactccaatg gccttgacac atagtcacac caaaatagat aatcagacta agtattatat   3660

aacaacgtga tccagacagt gagttctaag tgtattaatt aaatagcaaa aaattttgtt   3720

tttaaaaaat gaaagaggga gggttgccaa cctgaagtct taagtagatt gtttgggtag   3780

catatttcct tctttgaaca ttgtctgaaa ttttctataa atcaagactt cttgtacaaa   3840

gaatgatggg acatatgtaa taattcaggc aatcacctga gtaatttagg cagtccaaat   3900

tctttaccct gaaataccca cattttaaaa aaattgcaga taattgcttc agttatttac   3960

tttggggaca gagatatagt gtaaagtggg agaaactgag tccttttttg gtggtggtaa   4020

taataagatg ttataaaaat ataacatttt aaaaaagaaa ggtccagacc ttaagcgcag   4080

agctagaaca atatttttta aataatgggg ggaaaagggg gcactttggt aattttagaa   4140

atcaggtagt atactttttt tttttttttt gagacagggt cttgccatgt tgctcaggct   4200

ggtcttgaac tcctgggctc aagcaatcct cctgccttgg cctcccaaag tgctgggatt   4260

acaggcatga tccaccgtgc ccagccggta gacgtggtct taaaaacagt gtttacatgg   4320

ccatcttgat gcttagaaag ataattgatt aaaatttaat aaggcagggc caactccgag   4380

agttcattga caacggcagc aaaaaggccc tgaattctgt actttcttcc cccagcctcc   4440

ttctccagca aggagaatag cactcctccc tccagaagcc agctccctaa gttggagcca   4500

ctatgtaaga gaagaggaac gttcactttt taaaattcat atatttaaaa atcaagacca   4560

aaaagtaaat tctgtactcc tattattgac tgtagtcaat caaacataaa aaggtgaaag   4620

taaaatttaa ttttttaccc ttattttact gaccaatatg gaagttcttg gtatctttaa   4680

ggctgacctt cctggtattg tgtaatgatt gaatgtatct aaactgtaat aatttgaaac   4740

tgacaaacat aaccttctca gacttacaaa actatgttct ttctaaagat acagattttt   4800

attattttat tttgactagg aaggatttat aaataaatgt aatgaaaaat ctttgatctt   4860

aataaagtac cttcaaacag tg                                            4882


<210>  6395
<211>  576
<212>  PRT
<213>  Homo sapiens

<400>  6395

Met Pro Ala Leu Ser Thr Gly Ser Gly Ser Asp Thr Gly Leu Tyr Glu 
1               5                   10                  15


Leu Leu Ala Ala Leu Pro Ala Gln Leu Gln Pro His Val Asp Ser Gln 
            20                  25                  30


Glu Asp Leu Thr Phe Leu Trp Asp Met Phe Gly Glu Lys Ser Leu His 
        35                  40                  45


Ser Leu Val Lys Ile His Glu Lys Leu His Tyr Tyr Glu Lys Gln Ser 
    50                  55                  60


Pro Val Pro Ile Leu His Gly Ala Ala Ala Leu Ala Asp Asp Leu Ala 
65                  70                  75                  80


Glu Glu Leu Gln Asn Lys Pro Leu Asn Ser Glu Ile Arg Glu Leu Leu 
                85                  90                  95


Lys Leu Leu Ser Lys Pro Asn Val Lys Ala Leu Leu Ser Val His Asp 
            100                 105                 110


Thr Val Ala Gln Lys Asn Tyr Asp Pro Val Leu Pro Pro Met Pro Glu 
        115                 120                 125


Asp Ile Asp Asp Glu Glu Asp Ser Val Lys Ile Ile Arg Leu Val Lys 
    130                 135                 140


Asn Arg Glu Pro Leu Gly Ala Thr Ile Lys Lys Asp Glu Gln Thr Gly 
145                 150                 155                 160


Ala Ile Ile Val Ala Arg Ile Met Arg Gly Gly Ala Ala Asp Arg Ser 
                165                 170                 175


Gly Leu Ile His Val Gly Asp Glu Leu Arg Glu Val Asn Gly Ile Pro 
            180                 185                 190


Val Glu Asp Lys Arg Pro Glu Glu Ile Ile Gln Ile Leu Ala Gln Ser 
        195                 200                 205


Gln Gly Ala Ile Thr Phe Lys Ile Ile Pro Gly Ser Lys Glu Glu Thr 
    210                 215                 220


Pro Ser Lys Glu Gly Lys Met Phe Ile Lys Ala Leu Phe Asp Tyr Asn 
225                 230                 235                 240


Pro Asn Glu Asp Lys Ala Ile Pro Cys Lys Glu Ala Gly Leu Ser Phe 
                245                 250                 255


Lys Lys Gly Asp Ile Leu Gln Ile Met Ser Gln Asp Asp Ala Thr Trp 
            260                 265                 270


Trp Gln Ala Lys His Glu Ala Asp Ala Asn Pro Arg Ala Gly Leu Ile 
        275                 280                 285


Pro Ser Lys His Phe Gln Glu Arg Arg Leu Ala Leu Arg Arg Pro Glu 
    290                 295                 300


Ile Leu Val Gln Pro Leu Lys Val Ser Asn Arg Lys Ser Ser Gly Phe 
305                 310                 315                 320


Arg Lys Ser Phe Arg Leu Ser Arg Lys Asp Lys Lys Thr Asn Lys Ser 
                325                 330                 335


Met Tyr Glu Cys Lys Lys Ser Asp Gln Tyr Asp Thr Ala Asp Val Pro 
            340                 345                 350


Thr Tyr Glu Glu Val Thr Pro Tyr Arg Arg Gln Thr Asn Glu Lys Tyr 
        355                 360                 365


Arg Leu Val Val Leu Val Gly Pro Val Gly Val Gly Leu Asn Glu Leu 
    370                 375                 380


Lys Arg Lys Leu Leu Ile Ser Asp Thr Gln His Tyr Gly Val Thr Val 
385                 390                 395                 400


Pro His Thr Thr Arg Ala Arg Arg Ser Gln Glu Ser Asp Gly Val Glu 
                405                 410                 415


Tyr Ile Phe Ile Ser Lys His Leu Phe Glu Thr Asp Val Gln Asn Asn 
            420                 425                 430


Lys Phe Ile Glu Tyr Gly Glu Tyr Lys Asn Asn Tyr Tyr Gly Thr Ser 
        435                 440                 445


Ile Asp Ser Val Arg Ser Val Leu Ala Lys Asn Lys Val Cys Leu Leu 
    450                 455                 460


Asp Val Gln Pro His Thr Val Lys His Leu Arg Thr Leu Glu Phe Lys 
465                 470                 475                 480


Pro Tyr Val Ile Phe Ile Lys Pro Pro Ser Ile Glu Arg Leu Arg Glu 
                485                 490                 495


Thr Arg Lys Asn Ala Lys Ile Ile Ser Ser Arg Asp Asp Gln Gly Ala 
            500                 505                 510


Ala Lys Pro Phe Thr Glu Glu Asp Phe Gln Glu Met Ile Lys Ser Ala 
        515                 520                 525


Gln Ile Met Glu Ser Gln Tyr Gly His Leu Phe Asp Lys Ile Ile Ile 
    530                 535                 540


Asn Asp Asp Leu Thr Val Ala Phe Asn Glu Leu Lys Thr Thr Phe Asp 
545                 550                 555                 560


Lys Leu Glu Thr Glu Thr His Trp Val Pro Val Ser Trp Leu His Ser 
                565                 570                 575


<210>  6396
<211>  2145
<212>  DNA
<213>  Homo sapiens

<400>  6396
acagtgccaa tggaactaac aggaaccacc tgtgcacttc cttttacagg aatgttcata     60

aacagcaggt tctcctaggc tttgaacaaa atttagcttc tccaaggcca aaagcctcat    120

tgtgaagaga aagaaaggta tagcagtctt ggcagttgct gaactgaatt cctggctgat    180

ttccttactg cataaactca actgctctca ctgaggtcgt cattaagtcc tgtgtgtgtt    240

tgggcaggcc gacttgattt acagccagca ctccactgcg gaaacggctt acaaaatata    300

cagatcttgg tagacaacgt ggctgcaggc tgttgaattg gaattccctg tggctgtccg    360

aaggcagggt gtccggagag cggtgggctg acctgttcct acaccttgca tcatgccagc    420

tttgtcaacg ggatctggga gtgacactgg tctgtatgag ctgttggctg ctctgccagc    480

ccagctgcag ccacatgtgg atagccagga agacctgacc ttcctctggg atatgtttgg    540

tgaaaaaagc ctgcattcat tggtaaagat tcatgaaaaa ctacactact atgagaagca    600

gagtccggtg cccattctcc atggtgcggc ggccttggcc gatgatctgg ccgaagagct    660

tcagaacaag ccattaaaca gtgagatcag agagctgttg aaactactgt caaaacccaa    720

tgtgaaggct ttgctctctg tacatgatac tgtggctcag aagaattacg acccagtgtt    780

gcctcctatg cctgaagata ttgacgatga ggaagactca gtaaaaataa tccgtctggt    840

caaaaataga gaaccactgg gagctaccat taagaaggat gaacagaccg gggcgatcat    900

tgtggccaga atcatgagag gaggagctgc agatagaagt ggtcttattc atgttggtga    960

tgaacttagg gaagtcaacg ggataccagt ggaggataaa aggcctgagg aaataataca   1020

gattttggct cagtctcagg gagcaattac atttaagatt atacccggca gcaaagagga   1080

gacaccatca aaagaaggca agatgtttat caaagccctc tttgactata atcctaatga   1140

ggataaggca attccatgta aggaagctgg gctttctttc aaaaagggag atattcttca   1200

gattatgagc caagatgatg caacttggtg gcaagcgaaa cacgaagctg atgccaaccc   1260

cagggcaggc ttgatcccct caaagcattt ccaggaaagg agattggctt tgagacgacc   1320

agaaatattg gttcagcccc tgaaagtttc caacaggaaa tcatctggtt ttagaaaaag   1380

ttttcgtctt agtagaaaag ataagaaaac aaataaatcc atgtatgaat gcaagaagag   1440

tgatcagtac gacacagctg acgtacccac atacgaagaa gtgacaccgt atcggcgaca   1500

aactaatgaa aaatacagac tcgttgtctt ggttggtccc gtgggagtag ggctgaatga   1560

actgaaacga aagctgctga tcagtgacac ccagcactat ggcgtgacag tgccccatac   1620

caccagagca agaagaagcc aggagagtga tggtgttgaa tacattttca tttccaagca   1680

tttgtttgag acagatgtac aaaataacaa gtttattgaa tatggagaat ataaaaacaa   1740

ctactacggc acaagtatag actcagttcg gtctgtcctt gctaaaaaca aagtttgttt   1800

gttggatgtt cagcctcata cagtgaagca tttaaggaca ctagaattta agccctatgt   1860

gatatttata aagcctccat caatagagcg tttgagagaa acaagaaaaa atgcaaagat   1920

tatttcaagc agagatgacc aaggtgctgc aaaacccttc acagaagaag attttcaaga   1980

aatgattaaa tctgcacaga taatggaaag tcaatatggt catctttttg acaaaattat   2040

aataaatgat gacctcactg tggcattcaa tgagctcaaa acaacttttg acaaattaga   2100

gacagagacc cattgggtgc cagtgagctg gttacattca taact                   2145


<210>  6397
<211>  576
<212>  PRT
<213>  Homo sapiens

<400>  6397

Met Pro Ala Leu Ser Thr Gly Ser Gly Ser Asp Thr Gly Leu Tyr Glu 
1               5                   10                  15


Leu Leu Ala Ala Leu Pro Ala Gln Leu Gln Pro His Val Asp Ser Gln 
            20                  25                  30


Glu Asp Leu Thr Phe Leu Trp Asp Met Phe Gly Glu Lys Ser Leu His 
        35                  40                  45


Ser Leu Val Lys Ile His Glu Lys Leu His Tyr Tyr Glu Lys Gln Ser 
    50                  55                  60


Pro Val Pro Ile Leu His Gly Ala Ala Ala Leu Ala Asp Asp Leu Ala 
65                  70                  75                  80


Glu Glu Leu Gln Asn Lys Pro Leu Asn Ser Glu Ile Arg Glu Leu Leu 
                85                  90                  95


Lys Leu Leu Ser Lys Pro Asn Val Lys Ala Leu Leu Ser Val His Asp 
            100                 105                 110


Thr Val Ala Gln Lys Asn Tyr Asp Pro Val Leu Pro Pro Met Pro Glu 
        115                 120                 125


Asp Ile Asp Asp Glu Glu Asp Ser Val Lys Ile Ile Arg Leu Val Lys 
    130                 135                 140


Asn Arg Glu Pro Leu Gly Ala Thr Ile Lys Lys Asp Glu Gln Thr Gly 
145                 150                 155                 160


Ala Ile Ile Val Ala Arg Ile Met Arg Gly Gly Ala Ala Asp Arg Ser 
                165                 170                 175


Gly Leu Ile His Val Gly Asp Glu Leu Arg Glu Val Asn Gly Ile Pro 
            180                 185                 190


Val Glu Asp Lys Arg Pro Glu Glu Ile Ile Gln Ile Leu Ala Gln Ser 
        195                 200                 205


Gln Gly Ala Ile Thr Phe Lys Ile Ile Pro Gly Ser Lys Glu Glu Thr 
    210                 215                 220


Pro Ser Lys Glu Gly Lys Met Phe Ile Lys Ala Leu Phe Asp Tyr Asn 
225                 230                 235                 240


Pro Asn Glu Asp Lys Ala Ile Pro Cys Lys Glu Ala Gly Leu Ser Phe 
                245                 250                 255


Lys Lys Gly Asp Ile Leu Gln Ile Met Ser Gln Asp Asp Ala Thr Trp 
            260                 265                 270


Trp Gln Ala Lys His Glu Ala Asp Ala Asn Pro Arg Ala Gly Leu Ile 
        275                 280                 285


Pro Ser Lys His Phe Gln Glu Arg Arg Leu Ala Leu Arg Arg Pro Glu 
    290                 295                 300


Ile Leu Val Gln Pro Leu Lys Val Ser Asn Arg Lys Ser Ser Gly Phe 
305                 310                 315                 320


Arg Lys Ser Phe Arg Leu Ser Arg Lys Asp Lys Lys Thr Asn Lys Ser 
                325                 330                 335


Met Tyr Glu Cys Lys Lys Ser Asp Gln Tyr Asp Thr Ala Asp Val Pro 
            340                 345                 350


Thr Tyr Glu Glu Val Thr Pro Tyr Arg Arg Gln Thr Asn Glu Lys Tyr 
        355                 360                 365


Arg Leu Val Val Leu Val Gly Pro Val Gly Val Gly Leu Asn Glu Leu 
    370                 375                 380


Lys Arg Lys Leu Leu Ile Ser Asp Thr Gln His Tyr Gly Val Thr Val 
385                 390                 395                 400


Pro His Thr Thr Arg Ala Arg Arg Ser Gln Glu Ser Asp Gly Val Glu 
                405                 410                 415


Tyr Ile Phe Ile Ser Lys His Leu Phe Glu Thr Asp Val Gln Asn Asn 
            420                 425                 430


Lys Phe Ile Glu Tyr Gly Glu Tyr Lys Asn Asn Tyr Tyr Gly Thr Ser 
        435                 440                 445


Ile Asp Ser Val Arg Ser Val Leu Ala Lys Asn Lys Val Cys Leu Leu 
    450                 455                 460


Asp Val Gln Pro His Thr Val Lys His Leu Arg Thr Leu Glu Phe Lys 
465                 470                 475                 480


Pro Tyr Val Ile Phe Ile Lys Pro Pro Ser Ile Glu Arg Leu Arg Glu 
                485                 490                 495


Thr Arg Lys Asn Ala Lys Ile Ile Ser Ser Arg Asp Asp Gln Gly Ala 
            500                 505                 510


Ala Lys Pro Phe Thr Glu Glu Asp Phe Gln Glu Met Ile Lys Ser Ala 
        515                 520                 525


Gln Ile Met Glu Ser Gln Tyr Gly His Leu Phe Asp Lys Ile Ile Ile 
    530                 535                 540


Asn Asp Asp Leu Thr Val Ala Phe Asn Glu Leu Lys Thr Thr Phe Asp 
545                 550                 555                 560


Lys Leu Glu Thr Glu Thr His Trp Val Pro Val Ser Trp Leu His Ser 
                565                 570                 575


<210>  6398
<211>  697
<212>  DNA
<213>  Homo sapiens

<400>  6398
cgtgagaccc ttgcgcaagg tgctttccag ctgtgcctgg tgcagccggc gacccgcgag     60

cgcagctgtg ggcacgcccc cacctcttcc cacgccagag ttttcccctc tgctgggggc    120

accctccatt tctgcatggg aatccccggg gcacccaggc gggacgcgac ccgaaagaca    180

cgccggagac ccccaaccct ggattacctg cggccttggc gctcccacgc cggccgagcg    240

ctccagccgc ggccccccga aggttcggtg cgatgctggc tgcaggcctg tgggagccga    300

gcacgccggg ccactgggat ccggcggcgg cagcggcaga agcaggaacc agggcgccgg    360

accccagagc gtggcgcgca gtccagagcg gagcggacga gtgagacccg cgtcgcccgc    420

acgctcagac cgccctgctc tgcccctgac tcacggcgtc tgagcctgcc caggggcggc    480

gcagcggacg ccagccaccg cctccccgac ttttccattt cccctttctc tccgtaaaca    540

gaaagagact gcccggttgc aggtcctcga gccgctgtga agcagtcctc aagcggcagt    600

tatggcagtc cataaaggct cgggcacagc tggaagcaca cgtgacacag atgttggaac    660

aagtccagct agagacagat gaatatactc aacatct                             697


<210>  6399
<211>  133
<212>  PRT
<213>  Homo sapiens

<400>  6399

Met Gly Ile Pro Gly Ala Pro Arg Arg Asp Ala Thr Arg Lys Thr Arg 
1               5                   10                  15


Arg Arg Pro Pro Thr Leu Asp Tyr Leu Arg Pro Trp Arg Ser His Ala 
            20                  25                  30


Gly Arg Ala Leu Gln Pro Arg Pro Pro Glu Gly Ser Val Arg Cys Trp 
        35                  40                  45


Leu Gln Ala Cys Gly Ser Arg Ala Arg Arg Ala Thr Gly Ile Arg Arg 
    50                  55                  60


Arg Gln Arg Gln Lys Gln Glu Pro Gly Arg Arg Thr Pro Glu Arg Gly 
65                  70                  75                  80


Ala Gln Ser Arg Ala Glu Arg Thr Ser Glu Thr Arg Val Ala Arg Thr 
                85                  90                  95


Leu Arg Pro Pro Cys Ser Ala Pro Asp Ser Arg Arg Leu Ser Leu Pro 
            100                 105                 110


Arg Gly Gly Ala Ala Asp Ala Ser His Arg Leu Pro Asp Phe Ser Ile 
        115                 120                 125


Ser Pro Phe Ser Pro 
    130


<210>  6400
<211>  354
<212>  DNA
<213>  Homo sapiens

<400>  6400
gagctggtga aatggctggt ctagcagggt tctctcttgc ttctggctta atccagagca     60

ggttcatctg ttggggtaaa ttagaaggtt ttacttgaaa acgtatgtag agtttttaac    120

aaggaggcca aaagggagag agcaactgaa aagaaagaaa aagtctgtgg actccctgta    180

tgtatgtatg tatgtatgta tgtatgtatg tatgtatgta tgatgtattt gagacaggtt    240

ctggatctgt cgccctggct ggactgcatg agctgagatc gtgtcattgt acttcagcct    300

gggcgacaag agtgaaactc catttcaaaa ataaaaaata aaataaaaat aatt          354


<210>  6401
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  6401

Met Tyr Val Cys Met Tyr Val Cys Met Tyr Val Cys Met Tyr Asp Val 
1               5                   10                  15


Phe Glu Thr Gly Ser Gly Ser Val Ala Leu Ala Gly Leu His Glu Leu 
            20                  25                  30


Arg Ser Cys His Cys Thr Ser Ala Trp Ala Thr Arg Val Lys Leu His 
        35                  40                  45


Phe Lys Asn Lys Lys 
    50


<210>  6402
<211>  1237
<212>  DNA
<213>  Homo sapiens

<400>  6402
gctccgcccg ggcgcccaga gggcaaatga ggggcggcgg ggtggcgggt gggggggaga     60

cgcggaattt cccagcgcgg gggctctggc ttaccctgca accgggcagt ctctttctgt    120

ttacggagag aaaggggaaa tggaaaagtc ggggaggcgg tggctggcgt ccgctgcgcc    180

gcccctgggc aggctcagac gccgtgagtc aggggcagag cagggcggtc tgagcgtgcg    240

ggcgacgcgg gtctcactcg tccgctccgc tctggactgc gcgccacgct ctggggtccg    300

gcgccctggt tcctgcttct gccgctgccg ccgccggatc ccagtggccc ggcgtgctcg    360

gctcccacag gcctgcagcc agcatcgcac cgaaccttcg gggggccgcg gctggagcgc    420

tcggccggcg tgggagcgcc aaggccgcag atgcaatctt cttaccgcga agaagccagg    480

ggaataggta gccacatctt gtttgcagat aagaaaggaa gctaacgcag tatctgcaaa    540

gccaggagtc tgactcagta cttttctcac tcatgcatac aaagcagcta aaaatgacac    600

agcttattta ccatgcccct gacactgcac tgagcacttt atgagcttga actctgttaa    660

tcctcacgac cacctcatga gactctccag aaagagcaac agtaatggag tacatgagca    720

ctggaagtga caataaagaa gagattgatt tattaattaa acatttaaat gtgtctgatg    780

taatagacat tatggaaaat ctttatgcaa gtgaagagcc agcagtttat gaacccagtc    840

taatgaccat gtgtcaagac agtaatcaaa acgatgagcg ttctaagtct ctgctgctta    900

gtggccaaga ggtaccatgg ttgtcatcag tcagatatgg aactgtggag gatttgcttg    960

cttttgcaaa ccatatatcc aacactgcaa agcattttta tggacaacga ccacaggaat   1020

ctggaatttt attaaacatg gtacgtttct ttccgatcag ttgggtgcta tgtgctcagc   1080

tttcctactg cagcttcatt taatgcagag tggtgtttga atttggctta gatgggctgg   1140

caggcatgat tttaaaaaat gtaatcatca gtaagaagta cttccatgtt aaagatgcaa   1200

aaaaaaaagt cttcattaaa atttctattt aaagatt                            1237


<210>  6403
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6403

Met Glu Lys Ser Gly Arg Arg Trp Leu Ala Ser Ala Ala Pro Pro Leu 
1               5                   10                  15


Gly Arg Leu Arg Arg Arg Glu Ser Gly Ala Glu Gln Gly Gly Leu Ser 
            20                  25                  30


Val Arg Ala Thr Arg Val Ser Leu Val Arg Ser Ala Leu Asp Cys Ala 
        35                  40                  45


Pro Arg Ser Gly Val Arg Arg Pro Gly Ser Cys Phe Cys Arg Cys Arg 
    50                  55                  60


Arg Arg Ile Pro Val Ala Arg Arg Ala Arg Leu Pro Gln Ala Cys Ser 
65                  70                  75                  80


Gln His Arg Thr Glu Pro Ser Gly Gly Arg Gly Trp Ser Ala Arg Pro 
                85                  90                  95


Ala Trp Glu Arg Gln Gly Arg Arg Cys Asn Leu Leu Thr Ala Lys Lys 
            100                 105                 110


Pro Gly Glu 
        115


<210>  6404
<211>  2448
<212>  DNA
<213>  Homo sapiens

<400>  6404
gctccgcccg ggcgcccaga gggcaaatga ggggcggcgg ggtggcgggt gggggggaga     60

cgcggaattt cccagcgcgg gggctctggc ttaccctgca accgggcagt ctctttctgt    120

ttacggagag aaaggggaaa tggaaaagtc ggggaggcgg tggctggcgt ccgctgcgcc    180

gcccctgggc aggctcagac gccgtgagtc aggggcagag cagggcggtc tgagcgtgcg    240

ggcgacgcgg gtctcactcg tccgctccgc tctggactgc gcgccacgct ctggggtccg    300

gcgccctggt tcctgcttct gccgctgccg ccgccggatc ccagtggccc ggcgtgctcg    360

gctcccacag gcctgcagcc agcatcgcac cgaaccttcg gggggccgcg gctggagcgc    420

tcggccggcg tgggagcgcc aaggccgcag atgcaatctt cttaccgcga agaagccagg    480

ggaataggta gccacatctt gtttgcagat aagaaaggaa gctaacgcag tatctgcaaa    540

gccaggagtc tgactcagta cttttctcac tcatgcatac aaagcagcta aaaatgacac    600

agcttattta ccatgcccct gacactgcac tgagcacttt atgagcttga actctgttaa    660

tcctcacgac cacctcatga gactctccag aaagagcaac agtaatggag tacatgagca    720

ctggaagtga caataaagaa gagattgatt tattaattaa acatttaaat gtgtctgatg    780

taatagacat tatggaaaat ctttatgcaa gtgaagagcc agcagtttat gaacccagtc    840

taatgaccat gtgtcaagac agtaatcaaa acgatgagcg ttctaagtct ctgctgctta    900

gtggccaaga ggtaccatgg ttgtcatcag tcagatatgg aactgtggag gatttgcttg    960

cttttgcaaa ccatatatcc aacactgcaa agcattttta tggacaacga ccacaggaat   1020

ctggaatttt attaaacatg gtacgtttct ttccgatcag ttgggtgcta tgtgctcagc   1080

tttcctactg cagcttcatt taatgcagag tggtgtttga atttggctta gatgggctgg   1140

caggcatgat tttaaaaaat gtaatcatca gtaagaagta cttccatgtt aaagatgcaa   1200

aaaaaaaagt cttcattaaa atttctattt aaagattctt gatcatattt tagtagtatt   1260

tctacaaata ggtaattaag aagaatgtat tttggccggg tgcaggggct cacgcctgta   1320

atccgcgcac ttggagaggc cgaggtgggt ggatcacttg aggtcagcaa ttagagacca   1380

gtctggccaa catggtgaaa ccccgtctct actaaaaata caaaattagc ctggcatggt   1440

ggcgggtgcc tgtaattcca gctacctggg aggctgaggc acgagaatcc cttgaacctg   1500

ggaggtggag gttgtgatga gccgagatca caccactgca ctccagcctg tgtgactgag   1560

tgagactctg tctcaacaac aacaaagaag aatgtatttt aatttaacag ttcactaaaa   1620

agtttattca tcagttatgc agaaaagaaa ggcttaatga gactccttcg tctgagaggg   1680

gaataaacac tttgtcacta attaatcttg aaggctgaat tatttgttcc tttcttgtca   1740

catcttgaaa tgttattaat tcatttcttg caaaaatgta gtatgtaggc agtaaatagc   1800

tatccacaga ttcactctct ttcattggca aagtatgaat ggcaagtgat atatttgctt   1860

aatcatcgca agtatgcaaa tcatgcaaaa tattgtggca acattttgtt gccataatag   1920

tagatcaggt gatgtgttta ggtgtgcctg ggattctgtc aggcttttag tatgtcagag   1980

gtgaacgtag gtgctggcta aaggtaacct aatattttta aaaagaataa tttgcaaagg   2040

agtaggtggt agcttgcaaa acatgcttat tgatgaaagt gacgcccttt cttttggtgt   2100

atctaaatgg caaaatggct aatgttgggg gaaagtcggt gctgaatgag tgcggagtcc   2160

agaaaaagta cttaattatt ttgctttttt gcataccaca ttcatttaat taaaaacaac   2220

agagtaattt aggtcaggta tgtagtgaat tgttttgtca gaagccagtc atactcaacc   2280

atagctcaca atggagcaag ataatatttt gcattgttgt gtgactgctt tggtctggct   2340

ctatcaagct ctatttaata gtcgactaag tactttacct tcagaatatt tcttcctttt   2400

ataaatgaga aataatcatt tgaactagaa gccatatctg attttccc                2448


<210>  6405
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6405

Met Glu Lys Ser Gly Arg Arg Trp Leu Ala Ser Ala Ala Pro Pro Leu 
1               5                   10                  15


Gly Arg Leu Arg Arg Arg Glu Ser Gly Ala Glu Gln Gly Gly Leu Ser 
            20                  25                  30


Val Arg Ala Thr Arg Val Ser Leu Val Arg Ser Ala Leu Asp Cys Ala 
        35                  40                  45


Pro Arg Ser Gly Val Arg Arg Pro Gly Ser Cys Phe Cys Arg Cys Arg 
    50                  55                  60


Arg Arg Ile Pro Val Ala Arg Arg Ala Arg Leu Pro Gln Ala Cys Ser 
65                  70                  75                  80


Gln His Arg Thr Glu Pro Ser Gly Gly Arg Gly Trp Ser Ala Arg Pro 
                85                  90                  95


Ala Trp Glu Arg Gln Gly Arg Arg Cys Asn Leu Leu Thr Ala Lys Lys 
            100                 105                 110


Pro Gly Glu 
        115


<210>  6406
<211>  3620
<212>  DNA
<213>  Homo sapiens

<400>  6406
gctccgcccg ggcgcccaga gggcaaatga ggggcggcgg ggtggcgggt gggggggaga     60

cgcggaattt cccagcgcgg gggctctggc ttaccctgca accgggcagt ctctttctgt    120

ttacggagag aaaggggaaa tggaaaagtc ggggaggcgg tggctggcgt ccgctgcgcc    180

gcccctgggc aggctcagac gccgtgagtc aggggcagag cagggcggtc tgagcgtgcg    240

ggcgacgcgg gtctcactcg tccgctccgc tctggactgc gcgccacgct ctggggtccg    300

gcgccctggt tcctgcttct gccgctgccg ccgccggatc ccagtggccc ggcgtgctcg    360

gctcccacag gcctgcagcc agcatcgcac cgaaccttcg gggggccgcg gctggagcgc    420

tcggccggcg tgggagcgcc aaggccgcag atgcaatctt cttaccgcga agaagccagg    480

ggaataggta gccacatctt gtttgcagat aagaaaggaa gctaacgcag tatctgcaaa    540

gccaggagtc tgactcagta cttttctcac tcatgcatac aaagcagcta aaaatgacac    600

agcttattta ccatgcccct gacactgcac tgagcacttt atgagcttga actctgttaa    660

tcctcacgac cacctcatga gactctccag aaagagcaac agtaatggag tacatgagca    720

ctggaagtga caataaagaa gagattgatt tattaattaa acatttaaat gtgtctgatg    780

taatagacat tatggaaaat ctttatgcaa gtgaagagcc agcagtttat gaacccagtc    840

taatgaccat gtgtcaagac agtaatcaaa acgatgagcg ttctaagtct ctgctgctta    900

gtggccaaga ggtaccatgg ttgtcatcag tcagatatgg aactgtggag gatttgcttg    960

cttttgcaaa ccatatatcc aacactgcaa agcattttta tggacaacga ccacaggaat   1020

ctggaatttt attaaacatg gtcatcactc cccaaaatgg acgttaccaa atagattccg   1080

atgttctcct gatcccctgg aagctgactt acaggaatat tggttctgat tttattcctc   1140

ggggcgcctt tggaaaggta tacttggcac aagatataaa gacgaagaaa agaatggcgt   1200

gtaaactgat cccagtagat caatttaagc catctgatgt ggaaatccag gcttgcttcc   1260

ggcacgagaa catcgcagag ctgtatggcg cagtcctgtg gggtgaaact gtccatctct   1320

ttatggaagc aggcgaggga gggtctgttc tggagaaact ggagagctgt ggaccaatga   1380

gagaatttga aattatttgg gtgacaaagc atgttctcaa gggacttgat tttctacact   1440

caaagaaagt gatccatcat gatattaaac ctagcaacat tgttttcatg tccacaaaag   1500

ctgttttggt ggattttggc ctaagtgttc aaatgaccga agatgtctat tttcctaagg   1560

acctccgagg aacagagatt tacatgagcc cagaggtcat cctgtgcagg ggccattcaa   1620

ccaaagcaga catctacagc ctgggggcca cgctcatcca catgcagacg ggcaccccac   1680

cctgggtgaa gcgctaccct cgctcagcct atccctccta cctgtacata atccacaagc   1740

aagcacctcc actggaagac attgcagatg actgcagtcc agggatgaga gagctgatag   1800

aagcttccct ggagagaaac cccaatcacc gcccaagagc cgcagaccta ctaaaacatg   1860

aggccctgaa cccgcccaga gaggatcagc cacgctgtca gagtctggac tctgccctct   1920

tggagcgcaa gaggctgctg agtaggaagg agctggaact tcctgagaac attgctgatt   1980

cttcgtgcac aggaagcacc gaggaatctg agatgctcaa gaggcaacgc tctctctaca   2040

tcgacctcgg cgctctggct ggctacttca atcttgttcg gggaccacca acgcttgaat   2100

atggctgaag gatgccatgt ttgctctaaa ttaagacagc attgatctcc tggaggctgg   2160

ttctgctgcc tctacacagg ggccctgtac agtgaatggt gccattttcg aaggagcagt   2220

gtgacctcct gtgacccgtg aatgtgcctc caagcggccc tgtgtgtttg acatgtgaag   2280

ctatttgata tgcaccaggt ctcaaggttc tcatttctca ggtgacgtga ttctaaggca   2340

ggaatttgag agttcacaga aggatcgtgt ctgctgactg tttcattcac tgtgcacttt   2400

gctcaaaatt ttaaaaatac caatcacaag gataatagag tagcctaaaa ttactattct   2460

tggttcttat ttaagtatgg aatattcatt ttactcagaa tagctgtttt gtgtatattg   2520

gtgtatatta tataactctt tgagccttta ttggtaaatt ctggtataca ttgaattcat   2580

tataatttgg gtgactagaa caacttgaag attgtagcaa taagctggac tagtgtccta   2640

aaaatggcta actgatgaat tagaagccat ctgacagcag gccactagtg acagtttctt   2700

ttgtgttcct atggaaacat tttatactgt acatgctatg ctgaagacat tcaaaacgtg   2760

atgttttgaa tgtggataaa actgtgtaaa ccacataatt tttgtacatc ccaaaggatg   2820

agaatgtgac ctttaagaaa aatgaaaact tttgtaaatt attgatgatt ttgtaattct   2880

tatgactaaa ttttctttta agcatttgta tattaaaata gcatactgtg tatgttttat   2940

atcaaatgcc ttcatgaatc tttcatacat atatatattt gtaacattgt aaagtatgtg   3000

agtagtctta tgtaaagtat gtttttacat tatgcaaata aaacccaata cttttgtcca   3060

atgtggttgg tcaaatcaac tgaataaatt cagtattttg ccttagttgt tgtgaagcct   3120

gtgattctca gctgggactg aggatgggct ataggagttg agttatagat tggaaggaaa   3180

tgtgtatcat aagaaggcaa aaaataccag gagctttgca aattgtatta atacactcct   3240

tttctattgc tcttgtatga agctattgtc agctggaatg gtttgcatcc cccggtacat   3300

tgaggtagaa aaaacaattg tggttgtgcc tgtaatccca gcactttggg atgctgaagc   3360

gggaaaactg gttgagccca agagttcaag accagcctgg ccaacatgat gaaatcccat   3420

ctctacaaaa aatacaaaaa tttgccaggt gtgatggtgc atgcctgtag tcccagctac   3480

tcaggtggct gagatgtgag gatcacttaa gcctgggagg cgaaggttgc agtgagccaa   3540

gatcatgcca cactacactc cagcctggat aacagaggga ggccttgtcc ctgctaaaaa   3600

taaaataata attgtgtgcc                                               3620


<210>  6407
<211>  467
<212>  PRT
<213>  Homo sapiens

<400>  6407

Met Glu Tyr Met Ser Thr Gly Ser Asp Asn Lys Glu Glu Ile Asp Leu 
1               5                   10                  15


Leu Ile Lys His Leu Asn Val Ser Asp Val Ile Asp Ile Met Glu Asn 
            20                  25                  30


Leu Tyr Ala Ser Glu Glu Pro Ala Val Tyr Glu Pro Ser Leu Met Thr 
        35                  40                  45


Met Cys Gln Asp Ser Asn Gln Asn Asp Glu Arg Ser Lys Ser Leu Leu 
    50                  55                  60


Leu Ser Gly Gln Glu Val Pro Trp Leu Ser Ser Val Arg Tyr Gly Thr 
65                  70                  75                  80


Val Glu Asp Leu Leu Ala Phe Ala Asn His Ile Ser Asn Thr Ala Lys 
                85                  90                  95


His Phe Tyr Gly Gln Arg Pro Gln Glu Ser Gly Ile Leu Leu Asn Met 
            100                 105                 110


Val Ile Thr Pro Gln Asn Gly Arg Tyr Gln Ile Asp Ser Asp Val Leu 
        115                 120                 125


Leu Ile Pro Trp Lys Leu Thr Tyr Arg Asn Ile Gly Ser Asp Phe Ile 
    130                 135                 140


Pro Arg Gly Ala Phe Gly Lys Val Tyr Leu Ala Gln Asp Ile Lys Thr 
145                 150                 155                 160


Lys Lys Arg Met Ala Cys Lys Leu Ile Pro Val Asp Gln Phe Lys Pro 
                165                 170                 175


Ser Asp Val Glu Ile Gln Ala Cys Phe Arg His Glu Asn Ile Ala Glu 
            180                 185                 190


Leu Tyr Gly Ala Val Leu Trp Gly Glu Thr Val His Leu Phe Met Glu 
        195                 200                 205


Ala Gly Glu Gly Gly Ser Val Leu Glu Lys Leu Glu Ser Cys Gly Pro 
    210                 215                 220


Met Arg Glu Phe Glu Ile Ile Trp Val Thr Lys His Val Leu Lys Gly 
225                 230                 235                 240


Leu Asp Phe Leu His Ser Lys Lys Val Ile His His Asp Ile Lys Pro 
                245                 250                 255


Ser Asn Ile Val Phe Met Ser Thr Lys Ala Val Leu Val Asp Phe Gly 
            260                 265                 270


Leu Ser Val Gln Met Thr Glu Asp Val Tyr Phe Pro Lys Asp Leu Arg 
        275                 280                 285


Gly Thr Glu Ile Tyr Met Ser Pro Glu Val Ile Leu Cys Arg Gly His 
    290                 295                 300


Ser Thr Lys Ala Asp Ile Tyr Ser Leu Gly Ala Thr Leu Ile His Met 
305                 310                 315                 320


Gln Thr Gly Thr Pro Pro Trp Val Lys Arg Tyr Pro Arg Ser Ala Tyr 
                325                 330                 335


Pro Ser Tyr Leu Tyr Ile Ile His Lys Gln Ala Pro Pro Leu Glu Asp 
            340                 345                 350


Ile Ala Asp Asp Cys Ser Pro Gly Met Arg Glu Leu Ile Glu Ala Ser 
        355                 360                 365


Leu Glu Arg Asn Pro Asn His Arg Pro Arg Ala Ala Asp Leu Leu Lys 
    370                 375                 380


His Glu Ala Leu Asn Pro Pro Arg Glu Asp Gln Pro Arg Cys Gln Ser 
385                 390                 395                 400


Leu Asp Ser Ala Leu Leu Glu Arg Lys Arg Leu Leu Ser Arg Lys Glu 
                405                 410                 415


Leu Glu Leu Pro Glu Asn Ile Ala Asp Ser Ser Cys Thr Gly Ser Thr 
            420                 425                 430


Glu Glu Ser Glu Met Leu Lys Arg Gln Arg Ser Leu Tyr Ile Asp Leu 
        435                 440                 445


Gly Ala Leu Ala Gly Tyr Phe Asn Leu Val Arg Gly Pro Pro Thr Leu 
    450                 455                 460


Glu Tyr Gly 
465


<210>  6408
<211>  899
<212>  DNA
<213>  Homo sapiens

<400>  6408
gggcagagca gggcggtctg agcgtgcggg cgacgcgggt ctcactcgtc cgctccgctc     60

tggactgcgc gccacgctct ggggtccggc gccctggttc ctgcttctgc cgctgccgcc    120

gccggatccc agtggcccgg cgtgctcggc tcccacaggc ctgcagccag catcgcaccg    180

aaccttcggg gggccgcggc tggagcgctc ggccggcgtg ggagcgccaa ggccgcagat    240

gcaatcttct taccgcgaag aagccagggg aataggtagc cacatcttgt ttgcagataa    300

gaaaggaagc taacgcagta tctgcaaagc caggagtctg actcagtact tttctcactc    360

atgcatacaa agcagctaaa aatgacacag cttatttacc atgcccctga cactgcactg    420

agcactttat gagcttgaac tctgttaatc ctcacgacca cctcatgagg taggtgctgt    480

tattacttcc attttacaga tggggaaaat tgaggtcgag agaggttacg ttacttgctc    540

aacgtcatgc aagcagtaaa tgggagtgtg gggggaggca atgagatttg actccaagca    600

gtctgagacc agaggaatgt tggattgcag gatgctaaac tgctttcctc agacacaatt    660

catacgtcag aaaatgacca tcaagtaagt gaatgatgac actaaattgc atggttcttt    720

tgtcaaatga aattcactga gaggcagatg gctgggtcat gcgtgcaggt ggctctgcag    780

tggagcattt cctggagctt tgaaatgaag ctccagattg atcagacgtg cgtggcttta    840

gccctgagtg tcctgtgtgt taaaggcttg tgcttctcag aacttgaaat acctttcag     899


<210>  6409
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  6409

Met Lys Phe Thr Glu Arg Gln Met Ala Gly Ser Cys Val Gln Val Ala 
1               5                   10                  15


Leu Gln Trp Ser Ile Ser Trp Ser Phe Glu Met Lys Leu Gln Ile Asp 
            20                  25                  30


Gln Thr Cys Val Ala Leu Ala Leu Ser Val Leu Cys Val Lys Gly Leu 
        35                  40                  45


Cys Phe Ser Glu Leu Glu Ile Pro 
    50                  55


<210>  6410
<211>  3518
<212>  DNA
<213>  Homo sapiens

<400>  6410
ttcctgaaac ttgacctatt gccatcaaat ttgtgtagat tgaaatccat ttttccagct     60

tctggctttc agggcctgag ttttatttgc caagttagct cctgcattta gtgaagaggt    120

tatttttctt taaagtcacc agaggcataa aaaagccata gcgattcttg cagggagggt    180

gccacttcgg gggaatagct gggttgtgta aggttggaag ccctaaagag ccggtagcct    240

aaggtcttca aagatttctg agctgctctt gattcgtgtg tatgtttagt gaaagtttgt    300

tttcagtgcc tgtagctgat accactgact ctgtgagtaa gagtaagctc tctggatctc    360

aggtttccct ctgcaaagtg agctggacta aaggttatct taggtccctt tcaactctgc    420

actgtcaact tgaattcata cacacagttg acacagaacc ctcgttttct gaacaaaagc    480

atataaaatc ctgttgccaa tccttgtatg tcagtttccc atgggtcttg aatgcaaata    540

caaatatcgt aaactaaata tttgtgtttt ctttcctaga ctctccagaa agagcaacag    600

taatggagta catgagcact ggaagtgaca ataaagaaga gattgattta ttaattaaac    660

atttaaatgt gtctgatgta atagacatta tggaaaatct ttatgcaagt gaagagccag    720

cagtttatga acccagtcta atgaccatgt gtcaagacag taatcaaaac gatgagcgtt    780

ctaagtctct gctgcttagt ggccaagagg taccatggtt gtcatcagtc agatatggaa    840

ctgtggagga tttgcttgct tttgcaaacc atatatccaa cactgcaaag catttttatg    900

gacaacgacc acaggaatct ggaattttat taaacatggt catcactccc caaaatggac    960

gttaccaaat agattccgat gttctcctga tcccctggaa gctgacttac aggaatattg   1020

gttctgattt tattcctcgg ggcgcctttg gaaaggtata cttggcacaa gatataaaga   1080

cgaagaaaag aatggcgtgt aaactgatcc cagtagatca atttaagcca tctgatgtgg   1140

aaatccaggc ttgcttccgg cacgagaaca tcgcagagct gtatggcgca gtcctgtggg   1200

gtgaaactgt ccatctcttt atggaagcag gcgagggagg gtctgttctg gagaaactgg   1260

agagctgtgg accaatgaga gaatttgaaa ttatttgggt gacaaagcat gttctcaagg   1320

gacttgattt tctacactca aagaaagtga tccatcatga tattaaacct agcaacattg   1380

ttttcatgtc cacaaaagct gttttggtgg attttggcct aagtgttcaa atgaccgaag   1440

atgtctattt tcctaaggac ctccgaggaa cagagattta catgagccca gaggtcatcc   1500

tgtgcagggg ccattcaacc aaagcagaca tctacagcct gggggccacg ctcatccaca   1560

tgcagacggg caccccaccc tgggtgaagc gctaccctcg ctcagcctat ccctcctacc   1620

tgtacataat ccacaagcaa gcacctccac tggaagacat tgcagatgac tgcagtccag   1680

ggatgagaga gctgatagaa gcttccctgg agagaaaccc caatcaccgc ccaagagccg   1740

cagacctact aaaacatgag gccctgaacc cgcccagaga ggatcagcca cgctgtcaga   1800

gtctggactc tgccctcttg gagcgcaaga ggctgctgag taggaaggag ctggaacttc   1860

ctgagaacat tgctgattct tcgtgcacag gaagcaccga ggaatctgag atgctcaaga   1920

ggcaacgctc tctctacatc gacctcggcg ctctggctgg ctacttcaat cttgttcggg   1980

gaccaccaac gcttgaatat ggctgaagga tgccatgttt gctctaaatt aagacagcat   2040

tgatctcctg gaggctggtt ctgctgcctc tacacagggg ccctgtacag tgaatggtgc   2100

cattttcgaa ggagcagtgt gacctcctgt gacccgtgaa tgtgcctcca agcggccctg   2160

tgtgtttgac atgtgaagct atttgatatg caccaggtct caaggttctc atttctcagg   2220

tgacgtgatt ctaaggcagg aatttgagag ttcacagaag gatcgtgtct gctgactgtt   2280

tcattcactg tgcactttgc tcaaaatttt aaaaatacca atcacaagga taatagagta   2340

gcctaaaatt actattcttg gttcttattt aagtatggaa tattcatttt actcagaata   2400

gctgttttgt gtatattggt gtatattata taactctttg agcctttatt ggtaaattct   2460

ggtatacatt gaattcatta taatttgggt gactagaaca acttgaagat tgtagcaata   2520

agctggacta gtgtcctaaa aatggctaac tgatgaatta gaagccatct gacagcaggc   2580

cactagtgac agtttctttt gtgttcctat ggaaacattt tatactgtac atgctatgct   2640

gaagacattc aaaacgtgat gttttgaatg tggataaaac tgtgtaaacc acataatttt   2700

tgtacatccc aaaggatgag aatgtgacct ttaagaaaaa tgaaaacttt tgtaaattat   2760

tgatgatttt gtaattctta tgactaaatt ttcttttaag catttgtata ttaaaatagc   2820

atactgtgta tgttttatat caaatgcctt catgaatctt tcatacatat atatatttgt   2880

aacattgtaa agtatgtgag tagtcttatg taaagtatgt ttttacatta tgcaaataaa   2940

acccaatact tttgtccaat gtggttggtc aaatcaactg aataaattca gtattttgcc   3000

ttagttgttg tgaagcctgt gattctcagc tgggactgag gatgggctat aggagttgag   3060

ttatagattg gaaggaaatg tgtatcataa gaaggcaaaa aataccagga gctttgcaaa   3120

ttgtattaat acactccttt tctattgctc ttgtatgaag ctattgtcag ctggaatggt   3180

ttgcatcccc cggtacattg aggtagaaaa aacaattgtg gttgtgcctg taatcccagc   3240

actttgggat gctgaagcgg gaaaactggt tgagcccaag agttcaagac cagcctggcc   3300

aacatgatga aatcccatct ctacaaaaaa tacaaaaatt tgccaggtgt gatggtgcat   3360

gcctgtagtc ccagctactc aggtggctga gatgtgagga tcacttaagc ctgggaggcg   3420

aaggttgcag tgagccaaga tcatgccaca ctacactcca gcctggataa cagagggagg   3480

ccttgtccct gctaaaaata aaataataat tgtgtgcc                           3518


<210>  6411
<211>  467
<212>  PRT
<213>  Homo sapiens

<400>  6411

Met Glu Tyr Met Ser Thr Gly Ser Asp Asn Lys Glu Glu Ile Asp Leu 
1               5                   10                  15


Leu Ile Lys His Leu Asn Val Ser Asp Val Ile Asp Ile Met Glu Asn 
            20                  25                  30


Leu Tyr Ala Ser Glu Glu Pro Ala Val Tyr Glu Pro Ser Leu Met Thr 
        35                  40                  45


Met Cys Gln Asp Ser Asn Gln Asn Asp Glu Arg Ser Lys Ser Leu Leu 
    50                  55                  60


Leu Ser Gly Gln Glu Val Pro Trp Leu Ser Ser Val Arg Tyr Gly Thr 
65                  70                  75                  80


Val Glu Asp Leu Leu Ala Phe Ala Asn His Ile Ser Asn Thr Ala Lys 
                85                  90                  95


His Phe Tyr Gly Gln Arg Pro Gln Glu Ser Gly Ile Leu Leu Asn Met 
            100                 105                 110


Val Ile Thr Pro Gln Asn Gly Arg Tyr Gln Ile Asp Ser Asp Val Leu 
        115                 120                 125


Leu Ile Pro Trp Lys Leu Thr Tyr Arg Asn Ile Gly Ser Asp Phe Ile 
    130                 135                 140


Pro Arg Gly Ala Phe Gly Lys Val Tyr Leu Ala Gln Asp Ile Lys Thr 
145                 150                 155                 160


Lys Lys Arg Met Ala Cys Lys Leu Ile Pro Val Asp Gln Phe Lys Pro 
                165                 170                 175


Ser Asp Val Glu Ile Gln Ala Cys Phe Arg His Glu Asn Ile Ala Glu 
            180                 185                 190


Leu Tyr Gly Ala Val Leu Trp Gly Glu Thr Val His Leu Phe Met Glu 
        195                 200                 205


Ala Gly Glu Gly Gly Ser Val Leu Glu Lys Leu Glu Ser Cys Gly Pro 
    210                 215                 220


Met Arg Glu Phe Glu Ile Ile Trp Val Thr Lys His Val Leu Lys Gly 
225                 230                 235                 240


Leu Asp Phe Leu His Ser Lys Lys Val Ile His His Asp Ile Lys Pro 
                245                 250                 255


Ser Asn Ile Val Phe Met Ser Thr Lys Ala Val Leu Val Asp Phe Gly 
            260                 265                 270


Leu Ser Val Gln Met Thr Glu Asp Val Tyr Phe Pro Lys Asp Leu Arg 
        275                 280                 285


Gly Thr Glu Ile Tyr Met Ser Pro Glu Val Ile Leu Cys Arg Gly His 
    290                 295                 300


Ser Thr Lys Ala Asp Ile Tyr Ser Leu Gly Ala Thr Leu Ile His Met 
305                 310                 315                 320


Gln Thr Gly Thr Pro Pro Trp Val Lys Arg Tyr Pro Arg Ser Ala Tyr 
                325                 330                 335


Pro Ser Tyr Leu Tyr Ile Ile His Lys Gln Ala Pro Pro Leu Glu Asp 
            340                 345                 350


Ile Ala Asp Asp Cys Ser Pro Gly Met Arg Glu Leu Ile Glu Ala Ser 
        355                 360                 365


Leu Glu Arg Asn Pro Asn His Arg Pro Arg Ala Ala Asp Leu Leu Lys 
    370                 375                 380


His Glu Ala Leu Asn Pro Pro Arg Glu Asp Gln Pro Arg Cys Gln Ser 
385                 390                 395                 400


Leu Asp Ser Ala Leu Leu Glu Arg Lys Arg Leu Leu Ser Arg Lys Glu 
                405                 410                 415


Leu Glu Leu Pro Glu Asn Ile Ala Asp Ser Ser Cys Thr Gly Ser Thr 
            420                 425                 430


Glu Glu Ser Glu Met Leu Lys Arg Gln Arg Ser Leu Tyr Ile Asp Leu 
        435                 440                 445


Gly Ala Leu Ala Gly Tyr Phe Asn Leu Val Arg Gly Pro Pro Thr Leu 
    450                 455                 460


Glu Tyr Gly 
465


<210>  6412
<211>  594
<212>  DNA
<213>  Homo sapiens

<400>  6412
ggtgggagga tcaattgagc ccaggacttt gagacaagct taggcatcat agcaagaccc     60

catcttaata attatagaat tagagttaac tttataataa gtttagcact taaaaagcag    120

tatgttattt aatccttaca acaacccagt tgttgctatt gttattctta ttttacaatc    180

aaggaaataa gtttgcagag attaaaataa agtgtccaga gtcactcagt gacagaccct    240

ggacttgaac ccagttcttt ctaagtctaa ccctaaggtc taactgctac ataactttaa    300

aaaattataa tattacatac attattaaaa tatattagtg atataactaa tatcactgag    360

ttttggctca atgacagtct taactatggt cattaatatt tatgaggact ctaaaggcct    420

ctctttgagc ctaggaattc tataataaac ctcaagtagt gagcataaat gtatcttatt    480

taaagatgta aaacagcact catgtttaac tcatctgtga agcaaaaaac gacccagaaa    540

agcctttctt tcctgactct aaatgagatt ctgaaaaatg cgttcgcggg cttc          594


<210>  6413
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  6413

Met Phe Asn Ser Ser Val Lys Gln Lys Thr Thr Gln Lys Ser Leu Ser 
1               5                   10                  15


Phe Leu Thr Leu Asn Glu Ile Leu Lys Asn Ala Phe Ala Gly 
            20                  25                  30


<210>  6414
<211>  249
<212>  DNA
<213>  Homo sapiens

<400>  6414
atgtatgcaa ggccacacaa ggtgtatgga agagttgtgg agccaaagag aactgtctca     60

acagaagatt ctcaaagacc aggtgcccac ttagctgtga aaaagatatt tgttggtggc    120

attaaagaag acactgaaga atatcaccta agagattatt ttgaacagtg tggaaaaatt    180

gaagtgattg aaatcatgac tgaaacgagg cagcagcaag aaaaggggct ttgtctttgt    240

aacctttga                                                            249


<210>  6415
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  6415

Met Tyr Ala Arg Pro His Lys Val Tyr Gly Arg Val Val Glu Pro Lys 
1               5                   10                  15


Arg Thr Val Ser Thr Glu Asp Ser Gln Arg Pro Gly Ala His Leu Ala 
            20                  25                  30


Val Lys Lys Ile Phe Val Gly Gly Ile Lys Glu Asp Thr Glu Glu Tyr 
        35                  40                  45


His Leu Arg Asp Tyr Phe Glu Gln Cys Gly Lys Ile Glu Val Ile Glu 
    50                  55                  60


Ile Met Thr Glu Thr Arg Gln Gln Gln Glu Lys Gly Leu Cys Leu Cys 
65                  70                  75                  80


Asn Leu 



<210>  6416
<211>  571
<212>  DNA
<213>  Homo sapiens

<400>  6416
aacttttact ttcagttcag gggtacatgt gcaggtttgt tacataggta aacttgtgtc     60

atggggtttg ctgtacagat gatttcatca cccaggtatt aagcctagta cccattagtt    120

atttctcctg atcctctccc tccttccacc ttccatcctc tgataggaac cagtgtatgt    180

tgttcccctc tatgtgccca tatgttccca tcatttagct cccacttata agcgagaaca    240

tgcagtattt aattttctct tcctgtgcta gtttgctaag gatgatggcc tccagctcca    300

tccatgtctc tgcaaaagac atgatctcat tcttttttat ggctgcatgg ttgtccgtgg    360

tgtgtatgta ccacattttc tttatccagt ctaccattga tgggcattta gtagattcca    420

tgtctttgct attgtgaaca gtgttttggc aagatgaatg gatttaggag aaaactccac    480

cgttcggagt cacacgcgaa ggctggagct cagatgggtg agtagaggca aagctcattg    540

gtaggggtga tgggattgtt tgcagagaga c                                   571


<210>  6417
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  6417

Met Gln Tyr Leu Ile Phe Ser Ser Cys Ala Ser Leu Leu Arg Met Met 
1               5                   10                  15


Ala Ser Ser Ser Ile His Val Ser Ala Lys Asp Met Ile Ser Phe Phe 
            20                  25                  30


Phe Met Ala Ala Trp Leu Ser Val Val Cys Met Tyr His Ile Phe Phe 
        35                  40                  45


Ile Gln Ser Thr Ile Asp Gly His Leu Val Asp Ser Met Ser Leu Leu 
    50                  55                  60


Leu 
65


<210>  6418
<211>  541
<212>  DNA
<213>  Homo sapiens

<400>  6418
gcaacctgtg aagagaaata tttaagctaa tgtgttccat cgtgctggtg agcactttca     60

aaggagtgca tgaaagatat cacagcctca caaatgcaga gaaaagcctc ccttggccac    120

tgctgatcag gaagtgagac tttgtcctcc ccacagtgct atacctagcc ggctggatta    180

tcttcctcat ggccaaaagg agactagaca tggaaggcaa attgcagtta gatgaattta    240

accagctttc tctacaccgc atgaagccag cgactgtgag ggctctgcta cgcggctgag    300

cgggctgtgc aggcattgcc aaggtctcct cccttgttga cgttccctgc tcgtcttcac    360

gtgatcccat ctcagggctc tgccgtccac gccctcacca agctggatcc tggaagtcat    420

gcaattcctt cttccttact tctgtaaacc aaaaagtgtc tgagacagat ctcagtcaac    480

ttagaggttt attttgctga ggttgaggaa acactcagga aaaaagaaac acgagttaca    540

a                                                                    541


<210>  6419
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  6419

Met Ala Lys Arg Arg Leu Asp Met Glu Gly Lys Leu Gln Leu Asp Glu 
1               5                   10                  15


Phe Asn Gln Leu Ser Leu His Arg Met Lys Pro Ala Thr Val Arg Ala 
            20                  25                  30


Leu Leu Arg Gly 
        35


<210>  6420
<211>  4238
<212>  DNA
<213>  Homo sapiens

<400>  6420
gcggcggccg gccggggagg cggcctcggc gcacagtaat ggcagcgctg tgagcagggg     60

aacgcgagct gacagccgcc gccgccgccg cctccgccca ccttcctcgc cggggcttcg    120

tctttcactc cttcgggctg cctccccctc cccttgtccc ctgccccttg ccctgcttct    180

gcagaagatt tcaacactac acttgcacaa tgtctttgaa accaagagta gtagattttg    240

atgaaacatg gaacaaactt ttgacgacaa taaaagccgt ggtcatgttg gaatacgtcg    300

aaagagcaac atggaatgac cgtttctcag atatctatgc tttatgtgtg gcctatcctg    360

aaccccttgg agaaagactt tatacagaaa ctaagatttt tttggaaaat catgttcggc    420

atttgcataa gagagttttg gagtcagaag aacaagtact tgttatgtat cataggtact    480

gggaagaata cagcaagggt gcagactata tggactgctt atataggtat ctcaacaccc    540

agtttattaa aaagaataaa ttaacagaag cggaccttca gtatggctat ggtggtgtag    600

atatgaatga accacttatg gaaataggag agctagcatt ggatatgtgg aggaaattga    660

tggttgaacc acttcaggcc atccttatcc gaatgctgct ccgagaaatc aaaaatgatc    720

gtggtggaga agacccaaac cagaaagtaa tccatggggt tattaactcc tttgttcatg    780

ttgaacagta taagaaaaaa ttccccttaa agttttatca ggaaattttt gagtctccct    840

ttctgactga aacaggagag tattacaaac aagaagcttc aaatttatta caagaatcaa    900

actgctcaca gtatatggaa aaggttctag gtagattaaa agatgaagaa attcgatgtc    960

gaaaatacct acatccaagt tcatatacta aggtgattca tgaatgtcaa caacgaatgg   1020

tagcagacca cttacagttt ttacatgcag aatgtcataa tataattcga caagagaaaa   1080

aaaatgacat ggcaaatatg tacgtcttac tccgtgctgt gtccactggt ttacctcata   1140

tgattcagga gctgcaaaac cacatccatg atgagggcct tcgagcaacc agcaacctta   1200

ctcaggaaaa catgccaaca ctatttgtgg agtcagtttt ggaagtgcat ggtaaatttg   1260

ttcagcttat caacactgtt ttgaatggtg atcagcattt tatgagtgcg ttggataagg   1320

cccttacgtc agttgtaaat tacagagaac ctaagtctgt ttgcaaagca cctgaactgc   1380

ttgctaagta ctgtgacaac ttactgaaga agtcagcgaa agggatgaca gagaatgaag   1440

tggaagacag gctcacgagc ttcatcacag tgttcaaata cattgatgac aaggacgtct   1500

ttcaaaagtt ctacgcaaga atgctggcaa aacgtttaat tcatgggtta tccatgtcta   1560

tggactctga agaagccatg atcaacaaat taaagcaagc ctgtggttat gagtttacca   1620

gcaagctaca tcggatgtat acagatatga gtgtcagcgc tgatctcaac aataagttca   1680

acaattttat caaaaaccaa gacacagtaa tagatttggg aattagtttt caaatatatg   1740

ttctacaggc tggtgcgtgg cctcttactc aggctccttc atctacgttt gcaattcccc   1800

aggaattaga aaaaagtgta cagatgtttg aattatttta tagccaacat ttcagtggaa   1860

ggaaacttac atggttacat tatctgtgta caggtgaagt taaaatgaac tatttgggca   1920

aaccatatgt agccatggtt acaacatacc aaatggcagt tcttcttgcc tttaacaaca   1980

gtgaaactgt cagttataaa gagcttcagg acagcactca gatgaatgaa aaggaactga   2040

caaaaacaat caaatcatta cttgatgtga aaatgattaa ccatgattca gaaaaggaag   2100

atattgatgc agaatcttcg ttttcattaa atatgaactt tagcagtaaa agaacaaaat   2160

ttaaaattac tacatcaatg cagaaagaca caccacaaga aatggagcag actagaagtg   2220

cagttgatga ggaccggaaa atgtatctcc aagctgctat agttcgtatc atgaaagcac   2280

gaaaagtgct tcggcacaat gcccttattc aagaggtgat tagccagtca agagctaggt   2340

ttaatcccag tatcagcatg attaagaagt gtattgaagt tctgatagac aaacaataca   2400

tagaacgcag ccaggcgtcg gcagatgaat acagctacgt cgcgtgatgt cgctctcctc   2460

cagcgtggtg tgagaagatc attgccatca ccatttggtg tgttcctgtg ggaaaaagca   2520

ggactgtgcc tccataattt ggtcatttgg cagcccctgt tttctgctgt ttacaacatc   2580

accagtgcca cgtcatgagc gtcaaagaaa atgcctagag atatttcaag ctcatgtcat   2640

tatgacattt cttaaaactt tattaaaaga atgagtgaag tattgctgaa aagtggaaat   2700

tcggttgggt accatgcttt ttctcccctt cacgtttgca gttgatgtgt cttttttttt   2760

ttttttaatg tatcttaaag gacataaaat ttaaaaactt aaatattgta atatgacaga   2820

taacctaata attgtatcta cattaaaatg acaaacatga tactgctgct tgtcaaataa   2880

aaaaaaaata aagaaataga atgccttttt tatgtggatg gagtatcagg ttgaccacaa   2940

aatatattga ctcaaagcag ctaatgcatc tttagttgcg tttttatctg aatggtttaa   3000

ttcacttgta ctcctattta aatcctacat gaaaaatgtc tagattattg ttcttgactg   3060

cataggactg cattcagcat aaagaatgct ttatttttat ggattagata tattggatct   3120

aaacattttg aatcttgaag atgtaattcc atcagcagtt tctggtggtg tgctactcca   3180

cagacatcgc agagtgtgag caggatgctt ggtgacctca agtctggcac agagagagct   3240

tttcattcaa aagttgtctt tcttcggttg cataatccat taattctagc atagactagt   3300

accctagctc tgtggccttc cctgagtctt aggaaatcta tgataccaac atattccttc   3360

tatatgcctc ccctacctgt tacccttaca accctcctcc aacagtttag atactagagt   3420

cactctcatc aatcacagat gtgcttagca atgcataacc taaatacttt tttaaaaaag   3480

aaaattgtac attgtactgg gtgccacata tataaatccc attattttgt ttattttata   3540

tatatatata tatataatat atatatatat atatctcaac agcagtgtta agagtactgc   3600

gatctattat catatttatt gtctatccac accatcacca ccaccaccac acccctcctc   3660

cctcaacata caatttttct ttattttaaa aaaaataaga gacggggttt cgccatgttt   3720

cccaggctag tctggaactt ctggcctcaa gcaatcctat ctctgtctcc caaagtgctg   3780

ggattacaag catgagccac tgcatccatc caacacaaaa tttttaaaat cggaatattt   3840

taaagcaaat cacacaaatt atttcactta taatacttca gtaaggcctt taaaaaatcc   3900

acagtgatat tattactcct aacaaaaaca ataattactt agtatcatct aatatgtggt   3960

tcatatttaa atttgttgtt ttgagatggg tcttacaatt ggtttattca attgcatttt   4020

ttctaactcg tgtctcaagt gttttaaaaa tctactgaac ttataatgac ttatataatg   4080

tatttctcat tttacctttc ttccaaaaga ggaaataatg gcaaaccata taatattgta   4140

cattcactgt caaaaagcaa acccttgttt tgataacttg ttgattgata aaagttttcc   4200

aaattgattc ctttttttct taaatattta taaatgtt                           4238


<210>  6421
<211>  745
<212>  PRT
<213>  Homo sapiens

<400>  6421

Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys 
1               5                   10                  15


Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg 
            20                  25                  30


Ala Thr Trp Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala 
        35                  40                  45


Tyr Pro Glu Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe 
    50                  55                  60


Leu Glu Asn His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu 
65                  70                  75                  80


Glu Gln Val Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys 
                85                  90                  95


Gly Ala Asp Tyr Met Asp Cys Leu Tyr Arg Tyr Leu Asn Thr Gln Phe 
            100                 105                 110


Ile Lys Lys Asn Lys Leu Thr Glu Ala Asp Leu Gln Tyr Gly Tyr Gly 
        115                 120                 125


Gly Val Asp Met Asn Glu Pro Leu Met Glu Ile Gly Glu Leu Ala Leu 
    130                 135                 140


Asp Met Trp Arg Lys Leu Met Val Glu Pro Leu Gln Ala Ile Leu Ile 
145                 150                 155                 160


Arg Met Leu Leu Arg Glu Ile Lys Asn Asp Arg Gly Gly Glu Asp Pro 
                165                 170                 175


Asn Gln Lys Val Ile His Gly Val Ile Asn Ser Phe Val His Val Glu 
            180                 185                 190


Gln Tyr Lys Lys Lys Phe Pro Leu Lys Phe Tyr Gln Glu Ile Phe Glu 
        195                 200                 205


Ser Pro Phe Leu Thr Glu Thr Gly Glu Tyr Tyr Lys Gln Glu Ala Ser 
    210                 215                 220


Asn Leu Leu Gln Glu Ser Asn Cys Ser Gln Tyr Met Glu Lys Val Leu 
225                 230                 235                 240


Gly Arg Leu Lys Asp Glu Glu Ile Arg Cys Arg Lys Tyr Leu His Pro 
                245                 250                 255


Ser Ser Tyr Thr Lys Val Ile His Glu Cys Gln Gln Arg Met Val Ala 
            260                 265                 270


Asp His Leu Gln Phe Leu His Ala Glu Cys His Asn Ile Ile Arg Gln 
        275                 280                 285


Glu Lys Lys Asn Asp Met Ala Asn Met Tyr Val Leu Leu Arg Ala Val 
    290                 295                 300


Ser Thr Gly Leu Pro His Met Ile Gln Glu Leu Gln Asn His Ile His 
305                 310                 315                 320


Asp Glu Gly Leu Arg Ala Thr Ser Asn Leu Thr Gln Glu Asn Met Pro 
                325                 330                 335


Thr Leu Phe Val Glu Ser Val Leu Glu Val His Gly Lys Phe Val Gln 
            340                 345                 350


Leu Ile Asn Thr Val Leu Asn Gly Asp Gln His Phe Met Ser Ala Leu 
        355                 360                 365


Asp Lys Ala Leu Thr Ser Val Val Asn Tyr Arg Glu Pro Lys Ser Val 
    370                 375                 380


Cys Lys Ala Pro Glu Leu Leu Ala Lys Tyr Cys Asp Asn Leu Leu Lys 
385                 390                 395                 400


Lys Ser Ala Lys Gly Met Thr Glu Asn Glu Val Glu Asp Arg Leu Thr 
                405                 410                 415


Ser Phe Ile Thr Val Phe Lys Tyr Ile Asp Asp Lys Asp Val Phe Gln 
            420                 425                 430


Lys Phe Tyr Ala Arg Met Leu Ala Lys Arg Leu Ile His Gly Leu Ser 
        435                 440                 445


Met Ser Met Asp Ser Glu Glu Ala Met Ile Asn Lys Leu Lys Gln Ala 
    450                 455                 460


Cys Gly Tyr Glu Phe Thr Ser Lys Leu His Arg Met Tyr Thr Asp Met 
465                 470                 475                 480


Ser Val Ser Ala Asp Leu Asn Asn Lys Phe Asn Asn Phe Ile Lys Asn 
                485                 490                 495


Gln Asp Thr Val Ile Asp Leu Gly Ile Ser Phe Gln Ile Tyr Val Leu 
            500                 505                 510


Gln Ala Gly Ala Trp Pro Leu Thr Gln Ala Pro Ser Ser Thr Phe Ala 
        515                 520                 525


Ile Pro Gln Glu Leu Glu Lys Ser Val Gln Met Phe Glu Leu Phe Tyr 
    530                 535                 540


Ser Gln His Phe Ser Gly Arg Lys Leu Thr Trp Leu His Tyr Leu Cys 
545                 550                 555                 560


Thr Gly Glu Val Lys Met Asn Tyr Leu Gly Lys Pro Tyr Val Ala Met 
                565                 570                 575


Val Thr Thr Tyr Gln Met Ala Val Leu Leu Ala Phe Asn Asn Ser Glu 
            580                 585                 590


Thr Val Ser Tyr Lys Glu Leu Gln Asp Ser Thr Gln Met Asn Glu Lys 
        595                 600                 605


Glu Leu Thr Lys Thr Ile Lys Ser Leu Leu Asp Val Lys Met Ile Asn 
    610                 615                 620


His Asp Ser Glu Lys Glu Asp Ile Asp Ala Glu Ser Ser Phe Ser Leu 
625                 630                 635                 640


Asn Met Asn Phe Ser Ser Lys Arg Thr Lys Phe Lys Ile Thr Thr Ser 
                645                 650                 655


Met Gln Lys Asp Thr Pro Gln Glu Met Glu Gln Thr Arg Ser Ala Val 
            660                 665                 670


Asp Glu Asp Arg Lys Met Tyr Leu Gln Ala Ala Ile Val Arg Ile Met 
        675                 680                 685


Lys Ala Arg Lys Val Leu Arg His Asn Ala Leu Ile Gln Glu Val Ile 
    690                 695                 700


Ser Gln Ser Arg Ala Arg Phe Asn Pro Ser Ile Ser Met Ile Lys Lys 
705                 710                 715                 720


Cys Ile Glu Val Leu Ile Asp Lys Gln Tyr Ile Glu Arg Ser Gln Ala 
                725                 730                 735


Ser Ala Asp Glu Tyr Ser Tyr Val Ala 
            740                 745


<210>  6422
<211>  4264
<212>  DNA
<213>  Homo sapiens

<400>  6422
attgctttcc gggtggcggg ggggatttgg cagcagcgga agaaggagac cggagggtgt     60

gtgttgggca aagccggagg cagaggagga cgattgtttt acggatcccg tgatcggccc    120

gtccttctcc cctttccccc cctccctacc gcccctgtcc cgccggggag cggcggcggc    180

cttggacttt gctgtctttc ctcgcggaga cagatttcaa cactacactt gcacaatgtc    240

tttgaaacca agagtagtag attttgatga aacatggaac aaacttttga cgacaataaa    300

agccgtggtc atgttggaat acgtcgaaag agcaacatgg aatgaccgtt tctcagatat    360

ctatgcttta tgtgtggcct atcctgaacc ccttggagaa agactttata cagaaactaa    420

gatttttttg gaaaatcatg ttcggcattt gcataagaga gttttggagt cagaagaaca    480

agtacttgtt atgtatcata ggtactggga agaatacagc aagggtgcag actatatgga    540

ctgcttatat aggtatctca acacccagtt tattaaaaag aataaattaa cagaagcgga    600

ccttcagtat ggctatggtg gtgtagatat gaatgaacca cttatggaaa taggagagct    660

agcattggat atgtggagga aattgatggt tgaaccactt caggccatcc ttatccgaat    720

gctgctccga gaaatcaaaa atgatcgtgg tggagaagac ccaaaccaga aagtaatcca    780

tggggttatt aactcctttg ttcatgttga acagtataag aaaaaattcc ccttaaagtt    840

ttatcaggaa atttttgagt ctccctttct gactgaaaca ggagagtatt acaaacaaga    900

agcttcaaat ttattacaag aatcaaactg ctcacagtat atggaaaagg ttctaggtag    960

attaaaagat gaagaaattc gatgtcgaaa atacctacat ccaagttcat atactaaggt   1020

gattcatgaa tgtcaacaac gaatggtagc agaccactta cagtttttac atgcagaatg   1080

tcataatata attcgacaag agaaaaaaaa tgacatggca aatatgtacg tcttactccg   1140

tgctgtgtcc actggtttac ctcatatgat tcaggagctg caaaaccaca tccatgatga   1200

gggccttcga gcaaccagca accttactca ggaaaacatg ccaacactat ttgtggagtc   1260

agttttggaa gtgcatggta aatttgttca gcttatcaac actgttttga atggtgatca   1320

gcattttatg agtgcgttgg ataaggccct tacgtcagtt gtaaattaca gagaacctaa   1380

gtctgtttgc aaagcacctg aactgcttgc taagtactgt gacaacttac tgaagaagtc   1440

agcgaaaggg atgacagaga atgaagtgga agacaggctc acgagcttca tcacagtgtt   1500

caaatacatt gatgacaagg acgtctttca aaagttctac gcaagaatgc tggcaaaacg   1560

tttaattcat gggttatcca tgtctatgga ctctgaagaa gccatgatca acaaattaaa   1620

gcaagcctgt ggttatgagt ttaccagcaa gctacatcgg atgtatacag atatgagtgt   1680

cagcgctgat ctcaacaata agttcaacaa ttttatcaaa aaccaagaca cagtaataga   1740

tttgggaatt agttttcaaa tatatgttct acaggctggt gcgtggcctc ttactcaggc   1800

tccttcatct acgtttgcaa ttccccagga attagaaaaa agtgtacaga tgtttgaatt   1860

attttatagc caacatttca gtggaaggaa acttacatgg ttacattatc tgtgtacagg   1920

tgaagttaaa atgaactatt tgggcaaacc atatgtagcc atggttacaa cataccaaat   1980

ggcagttctt cttgccttta acaacagtga aactgtcagt tataaagagc ttcaggacag   2040

cactcagatg aatgaaaagg aactgacaaa aacaatcaaa tcattacttg atgtgaaaat   2100

gattaaccat gattcagaaa aggaagatat tgatgcagaa tcttcgtttt cattaaatat   2160

gaactttagc agtaaaagaa caaaatttaa aattactaca tcaatgcaga aagacacacc   2220

acaagaaatg gagcagacta gaagtgcagt tgatgaggac cggaaaatgt atctccaagc   2280

tgctatagtt cgtatcatga aagcacgaaa agtgcttcgg cacaatgccc ttattcaaga   2340

ggtgattagc cagtcaagag ctaggtttaa tcccagtatc agcatgatta agaagtgtat   2400

tgaagttctg atagacaaac aatacataga acgcagccag gcgtcggcag atgaatacag   2460

ctacgtcgcg tgatgtcgct ctcctccagc gtggtgtgag aagatcattg ccatcaccat   2520

ttggtgtgtt cctgtgggaa aaagcaggac tgtgcctcca taatttggtc atttggcagc   2580

ccctgttttc tgctgtttac aacatcacca gtgccacgtc atgagcgtca aagaaaatgc   2640

ctagagatat ttcaagctca tgtcattatg acatttctta aaactttatt aaaagaatga   2700

gtgaagtatt gctgaaaagt ggaaattcgg ttgggtacca tgctttttct ccccttcacg   2760

tttgcagttg atgtgtcttt tttttttttt ttaatgtatc ttaaaggaca taaaatttaa   2820

aaacttaaat attgtaatat gacagataac ctaataattg tatctacatt aaaatgacaa   2880

acatgatact gctgcttgtc aaataaaaaa aaaataaaga aatagaatgc cttttttatg   2940

tggatggagt atcaggttga ccacaaaata tattgactca aagcagctaa tgcatcttta   3000

gttgcgtttt tatctgaatg gtttaattca cttgtactcc tatttaaatc ctacatgaaa   3060

aatgtctaga ttattgttct tgactgcata ggactgcatt cagcataaag aatgctttat   3120

ttttatggat tagatatatt ggatctaaac attttgaatc ttgaagatgt aattccatca   3180

gcagtttctg gtggtgtgct actccacaga catcgcagag tgtgagcagg atgcttggtg   3240

acctcaagtc tggcacagag agagcttttc attcaaaagt tgtctttctt cggttgcata   3300

atccattaat tctagcatag actagtaccc tagctctgtg gccttccctg agtcttagga   3360

aatctatgat accaacatat tccttctata tgcctcccct acctgttacc cttacaaccc   3420

tcctccaaca gtttagatac tagagtcact ctcatcaatc acagatgtgc ttagcaatgc   3480

ataacctaaa tactttttta aaaaagaaaa ttgtacattg tactgggtgc cacatatata   3540

aatcccatta ttttgtttat tttatatata tatatatata taatatatat atatatatat   3600

ctcaacagca gtgttaagag tactgcgatc tattatcata tttattgtct atccacacca   3660

tcaccaccac caccacaccc ctcctccctc aacatacaat ttttctttat tttaaaaaaa   3720

ataagagacg gggtttcgcc atgtttccca ggctagtctg gaacttctgg cctcaagcaa   3780

tcctatctct gtctcccaaa gtgctgggat tacaagcatg agccactgca tccatccaac   3840

acaaaatttt taaaatcgga atattttaaa gcaaatcaca caaattattt cacttataat   3900

acttcagtaa ggcctttaaa aaatccacag tgatattatt actcctaaca aaaacaataa   3960

ttacttagta tcatctaata tgtggttcat atttaaattt gttgttttga gatgggtctt   4020

acaattggtt tattcaattg cattttttct aactcgtgtc tcaagtgttt taaaaatcta   4080

ctgaacttat aatgacttat ataatgtatt tctcatttta cctttcttcc aaaagaggaa   4140

ataatggcaa accatataat attgtacatt cactgtcaaa aagcaaaccc ttgttttgat   4200

aacttgttga ttgataaaag ttttccaaat tgattccttt ttttcttaaa tatttataaa   4260

tgtt                                                                4264


<210>  6423
<211>  745
<212>  PRT
<213>  Homo sapiens

<400>  6423

Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys 
1               5                   10                  15


Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg 
            20                  25                  30


Ala Thr Trp Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala 
        35                  40                  45


Tyr Pro Glu Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe 
    50                  55                  60


Leu Glu Asn His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu 
65                  70                  75                  80


Glu Gln Val Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys 
                85                  90                  95


Gly Ala Asp Tyr Met Asp Cys Leu Tyr Arg Tyr Leu Asn Thr Gln Phe 
            100                 105                 110


Ile Lys Lys Asn Lys Leu Thr Glu Ala Asp Leu Gln Tyr Gly Tyr Gly 
        115                 120                 125


Gly Val Asp Met Asn Glu Pro Leu Met Glu Ile Gly Glu Leu Ala Leu 
    130                 135                 140


Asp Met Trp Arg Lys Leu Met Val Glu Pro Leu Gln Ala Ile Leu Ile 
145                 150                 155                 160


Arg Met Leu Leu Arg Glu Ile Lys Asn Asp Arg Gly Gly Glu Asp Pro 
                165                 170                 175


Asn Gln Lys Val Ile His Gly Val Ile Asn Ser Phe Val His Val Glu 
            180                 185                 190


Gln Tyr Lys Lys Lys Phe Pro Leu Lys Phe Tyr Gln Glu Ile Phe Glu 
        195                 200                 205


Ser Pro Phe Leu Thr Glu Thr Gly Glu Tyr Tyr Lys Gln Glu Ala Ser 
    210                 215                 220


Asn Leu Leu Gln Glu Ser Asn Cys Ser Gln Tyr Met Glu Lys Val Leu 
225                 230                 235                 240


Gly Arg Leu Lys Asp Glu Glu Ile Arg Cys Arg Lys Tyr Leu His Pro 
                245                 250                 255


Ser Ser Tyr Thr Lys Val Ile His Glu Cys Gln Gln Arg Met Val Ala 
            260                 265                 270


Asp His Leu Gln Phe Leu His Ala Glu Cys His Asn Ile Ile Arg Gln 
        275                 280                 285


Glu Lys Lys Asn Asp Met Ala Asn Met Tyr Val Leu Leu Arg Ala Val 
    290                 295                 300


Ser Thr Gly Leu Pro His Met Ile Gln Glu Leu Gln Asn His Ile His 
305                 310                 315                 320


Asp Glu Gly Leu Arg Ala Thr Ser Asn Leu Thr Gln Glu Asn Met Pro 
                325                 330                 335


Thr Leu Phe Val Glu Ser Val Leu Glu Val His Gly Lys Phe Val Gln 
            340                 345                 350


Leu Ile Asn Thr Val Leu Asn Gly Asp Gln His Phe Met Ser Ala Leu 
        355                 360                 365


Asp Lys Ala Leu Thr Ser Val Val Asn Tyr Arg Glu Pro Lys Ser Val 
    370                 375                 380


Cys Lys Ala Pro Glu Leu Leu Ala Lys Tyr Cys Asp Asn Leu Leu Lys 
385                 390                 395                 400


Lys Ser Ala Lys Gly Met Thr Glu Asn Glu Val Glu Asp Arg Leu Thr 
                405                 410                 415


Ser Phe Ile Thr Val Phe Lys Tyr Ile Asp Asp Lys Asp Val Phe Gln 
            420                 425                 430


Lys Phe Tyr Ala Arg Met Leu Ala Lys Arg Leu Ile His Gly Leu Ser 
        435                 440                 445


Met Ser Met Asp Ser Glu Glu Ala Met Ile Asn Lys Leu Lys Gln Ala 
    450                 455                 460


Cys Gly Tyr Glu Phe Thr Ser Lys Leu His Arg Met Tyr Thr Asp Met 
465                 470                 475                 480


Ser Val Ser Ala Asp Leu Asn Asn Lys Phe Asn Asn Phe Ile Lys Asn 
                485                 490                 495


Gln Asp Thr Val Ile Asp Leu Gly Ile Ser Phe Gln Ile Tyr Val Leu 
            500                 505                 510


Gln Ala Gly Ala Trp Pro Leu Thr Gln Ala Pro Ser Ser Thr Phe Ala 
        515                 520                 525


Ile Pro Gln Glu Leu Glu Lys Ser Val Gln Met Phe Glu Leu Phe Tyr 
    530                 535                 540


Ser Gln His Phe Ser Gly Arg Lys Leu Thr Trp Leu His Tyr Leu Cys 
545                 550                 555                 560


Thr Gly Glu Val Lys Met Asn Tyr Leu Gly Lys Pro Tyr Val Ala Met 
                565                 570                 575


Val Thr Thr Tyr Gln Met Ala Val Leu Leu Ala Phe Asn Asn Ser Glu 
            580                 585                 590


Thr Val Ser Tyr Lys Glu Leu Gln Asp Ser Thr Gln Met Asn Glu Lys 
        595                 600                 605


Glu Leu Thr Lys Thr Ile Lys Ser Leu Leu Asp Val Lys Met Ile Asn 
    610                 615                 620


His Asp Ser Glu Lys Glu Asp Ile Asp Ala Glu Ser Ser Phe Ser Leu 
625                 630                 635                 640


Asn Met Asn Phe Ser Ser Lys Arg Thr Lys Phe Lys Ile Thr Thr Ser 
                645                 650                 655


Met Gln Lys Asp Thr Pro Gln Glu Met Glu Gln Thr Arg Ser Ala Val 
            660                 665                 670


Asp Glu Asp Arg Lys Met Tyr Leu Gln Ala Ala Ile Val Arg Ile Met 
        675                 680                 685


Lys Ala Arg Lys Val Leu Arg His Asn Ala Leu Ile Gln Glu Val Ile 
    690                 695                 700


Ser Gln Ser Arg Ala Arg Phe Asn Pro Ser Ile Ser Met Ile Lys Lys 
705                 710                 715                 720


Cys Ile Glu Val Leu Ile Asp Lys Gln Tyr Ile Glu Arg Ser Gln Ala 
                725                 730                 735


Ser Ala Asp Glu Tyr Ser Tyr Val Ala 
            740                 745


<210>  6424
<211>  2906
<212>  DNA
<213>  Homo sapiens

<400>  6424
ggcggcggcc ggccggggag gcggcctcgg cgcacagtaa tggcagcgct gtgagcaggg     60

gaacgcgagc tgacagccgc cgccgccgcc gcctccgccc accttcctcg ccggggcttc    120

gtctttcact ccttcgggct gcctccccct ccccttgtcc cctgcccctt gccctgcttc    180

tgcagaagat ttcaacacta cacttgcaca atgtctttga aaccaagagt agtagatttt    240

gatgaaacat ggaacaaact tttgacgaca ataaaagccg tggtcatgtt ggaatacgtc    300

gaaagagcaa catggaatga ccgtttctca gatatctatg ctttatgtgt ggcctatcct    360

gaaccccttg gagaaagact ttatacagaa actaagattt ttttggaaaa tcatgttcgg    420

catttgcata agagagtttt ggagtcagaa gaacaagtac ttgttatgta tcataggtac    480

tgggaagaat acagcaaggg tgcagactat atggactgct tatataggta tctcaacacc    540

cagtttatta aaaagaataa attaacagaa gcggaccttc agtatggcta tggtggtgta    600

gatatgaatg aaccacttat ggaaatagga gagctagcat tggatatgtg gaggaaattg    660

atggttgaac cacttcaggc catccttatc cgaatgctgc tccgagaaat caaaaatgat    720

cgtggtggag aagacccaaa ccagaaagta atccatgggg ttattaactc ctttgttcat    780

gttgaacagt ataagaaaaa attcccctta aagttttatc aggaaatttt tgagtctccc    840

tttctgactg aaacaggaga gtattacaaa caagaagctt caaatttatt acaagaatca    900

aactgctcac agtatatgga aaaggttcta ggtagattaa aagatgaaga aattcgatgt    960

cgaaaatacc tacatccaag ttcatatact aaggtgattc atgaatgtca acaacgaatg   1020

gtagcagacc acttacagtt tttacatgca gaatgtcata atataattcg acaagagaaa   1080

aaaaatgaca tggcaaatat gtacgtctta ctccgtgctg tgtccactgg tttacctcat   1140

atgattcagg agctgcaaaa ccacatccat gatgagggcc ttcgagcaac cagcaacctt   1200

actcaggaaa acatgccaac actatttgtg gagtcagttt tggaagtgca tggtaaattt   1260

gttcagctta tcaacactgt tttgaatggt gatcagcatt ttatgagtgc gttggataag   1320

gcccttacgt cagttgtaaa ttacagagaa cctaagtctg tttgcaaagc acctgaactg   1380

cttgctaagt actgtgacaa cttactgaag aagtcagcga aagggatgac agagaatgaa   1440

gtggaagaca ggctcacgag cttcatcaca gtgttcaaat acattgatga caaggacgtc   1500

tttcaaaagt tctacgcaag aatgctggca aaacgtttaa ttcatgggtt atccatgtct   1560

atggactctg aagaagccat gatcaacaaa ttaaagcaag cctgtggtta tgagtttacc   1620

agcaagctac atcggatgta tacagatatg agtgtcagcg ctgatctcaa caataagttc   1680

aacaatttta tcaaaaacca agacacagta atagatttgg gaattagttt tcaaatatat   1740

gttctacagg ctggtgcgtg gcctcttact caggctcctt catctacgtt tgcaattccc   1800

caggaattag aaaaaagtgt acagatgttt gaattatttt atagccaaca tttcagtgga   1860

aggaaactta catggttaca ttatctgtgt acaggtgaag ttaaaatgaa ctatttgggc   1920

aaaccatatg tagccatggt tacaacatac caaatggcag ttcttcttgc ctttaacaac   1980

agtgaaactg tcagttataa agagcttcag gacagcactc agatgaatga aaaggaactg   2040

acaaaaacaa tcaaatcatt acttgatgtg aaaatgatta accatgattc agaaaaggaa   2100

gatattgatg cagaatcttc gttttcatta aatatgaact ttagcagtaa aagaacaaaa   2160

tttaaaatta ctacatcaat gcagaaagac acaccacaag aaatggagca gactagaagt   2220

gcagttgatg aggaccggaa aatgtatctc caagctgcta tagttcgtat catgaaagca   2280

cgaaaagtgc ttcggcacaa tgcccttatt caagaggtga ttagccagtc aagagctagg   2340

tttaatccca gtatcagcat gattaagaag tgtattgaag ttctgataga caaacaatac   2400

atagaacgca gccaggcgtc ggcagatgaa tacagctacg tcgcgtgatg tcgctctcct   2460

ccagcgtggt gtgagaagat cattgccatc accatttggt gtgttcctgt gggaaaaagc   2520

aggactgtgc ctccataatt tggtcatttg gcagcccctg ttttctgctg tttacaacat   2580

caccagtgcc acgtcatgag cgtcaaagaa aatgcctaga gatatttcaa gctcatgtca   2640

ttatgacatt tcttaaaact ttattaaaag aatgagtgaa gtattgctga aaagtggaaa   2700

ttcggttggg taccatgctt tttctcccct tcacgtttgc agttgatgtg tctttttttt   2760

tttttttaat gtatcttaaa ggacataaaa tttaaaaact taaatattgt aatatgacag   2820

ataacctaat aattgtatct acattaaaat gacaaacatg atactgctgc ttgtcaaata   2880

aaaaaaaaat aaagaaatag aatgcc                                        2906


<210>  6425
<211>  745
<212>  PRT
<213>  Homo sapiens

<400>  6425

Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys 
1               5                   10                  15


Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg 
            20                  25                  30


Ala Thr Trp Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala 
        35                  40                  45


Tyr Pro Glu Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe 
    50                  55                  60


Leu Glu Asn His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu 
65                  70                  75                  80


Glu Gln Val Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys 
                85                  90                  95


Gly Ala Asp Tyr Met Asp Cys Leu Tyr Arg Tyr Leu Asn Thr Gln Phe 
            100                 105                 110


Ile Lys Lys Asn Lys Leu Thr Glu Ala Asp Leu Gln Tyr Gly Tyr Gly 
        115                 120                 125


Gly Val Asp Met Asn Glu Pro Leu Met Glu Ile Gly Glu Leu Ala Leu 
    130                 135                 140


Asp Met Trp Arg Lys Leu Met Val Glu Pro Leu Gln Ala Ile Leu Ile 
145                 150                 155                 160


Arg Met Leu Leu Arg Glu Ile Lys Asn Asp Arg Gly Gly Glu Asp Pro 
                165                 170                 175


Asn Gln Lys Val Ile His Gly Val Ile Asn Ser Phe Val His Val Glu 
            180                 185                 190


Gln Tyr Lys Lys Lys Phe Pro Leu Lys Phe Tyr Gln Glu Ile Phe Glu 
        195                 200                 205


Ser Pro Phe Leu Thr Glu Thr Gly Glu Tyr Tyr Lys Gln Glu Ala Ser 
    210                 215                 220


Asn Leu Leu Gln Glu Ser Asn Cys Ser Gln Tyr Met Glu Lys Val Leu 
225                 230                 235                 240


Gly Arg Leu Lys Asp Glu Glu Ile Arg Cys Arg Lys Tyr Leu His Pro 
                245                 250                 255


Ser Ser Tyr Thr Lys Val Ile His Glu Cys Gln Gln Arg Met Val Ala 
            260                 265                 270


Asp His Leu Gln Phe Leu His Ala Glu Cys His Asn Ile Ile Arg Gln 
        275                 280                 285


Glu Lys Lys Asn Asp Met Ala Asn Met Tyr Val Leu Leu Arg Ala Val 
    290                 295                 300


Ser Thr Gly Leu Pro His Met Ile Gln Glu Leu Gln Asn His Ile His 
305                 310                 315                 320


Asp Glu Gly Leu Arg Ala Thr Ser Asn Leu Thr Gln Glu Asn Met Pro 
                325                 330                 335


Thr Leu Phe Val Glu Ser Val Leu Glu Val His Gly Lys Phe Val Gln 
            340                 345                 350


Leu Ile Asn Thr Val Leu Asn Gly Asp Gln His Phe Met Ser Ala Leu 
        355                 360                 365


Asp Lys Ala Leu Thr Ser Val Val Asn Tyr Arg Glu Pro Lys Ser Val 
    370                 375                 380


Cys Lys Ala Pro Glu Leu Leu Ala Lys Tyr Cys Asp Asn Leu Leu Lys 
385                 390                 395                 400


Lys Ser Ala Lys Gly Met Thr Glu Asn Glu Val Glu Asp Arg Leu Thr 
                405                 410                 415


Ser Phe Ile Thr Val Phe Lys Tyr Ile Asp Asp Lys Asp Val Phe Gln 
            420                 425                 430


Lys Phe Tyr Ala Arg Met Leu Ala Lys Arg Leu Ile His Gly Leu Ser 
        435                 440                 445


Met Ser Met Asp Ser Glu Glu Ala Met Ile Asn Lys Leu Lys Gln Ala 
    450                 455                 460


Cys Gly Tyr Glu Phe Thr Ser Lys Leu His Arg Met Tyr Thr Asp Met 
465                 470                 475                 480


Ser Val Ser Ala Asp Leu Asn Asn Lys Phe Asn Asn Phe Ile Lys Asn 
                485                 490                 495


Gln Asp Thr Val Ile Asp Leu Gly Ile Ser Phe Gln Ile Tyr Val Leu 
            500                 505                 510


Gln Ala Gly Ala Trp Pro Leu Thr Gln Ala Pro Ser Ser Thr Phe Ala 
        515                 520                 525


Ile Pro Gln Glu Leu Glu Lys Ser Val Gln Met Phe Glu Leu Phe Tyr 
    530                 535                 540


Ser Gln His Phe Ser Gly Arg Lys Leu Thr Trp Leu His Tyr Leu Cys 
545                 550                 555                 560


Thr Gly Glu Val Lys Met Asn Tyr Leu Gly Lys Pro Tyr Val Ala Met 
                565                 570                 575


Val Thr Thr Tyr Gln Met Ala Val Leu Leu Ala Phe Asn Asn Ser Glu 
            580                 585                 590


Thr Val Ser Tyr Lys Glu Leu Gln Asp Ser Thr Gln Met Asn Glu Lys 
        595                 600                 605


Glu Leu Thr Lys Thr Ile Lys Ser Leu Leu Asp Val Lys Met Ile Asn 
    610                 615                 620


His Asp Ser Glu Lys Glu Asp Ile Asp Ala Glu Ser Ser Phe Ser Leu 
625                 630                 635                 640


Asn Met Asn Phe Ser Ser Lys Arg Thr Lys Phe Lys Ile Thr Thr Ser 
                645                 650                 655


Met Gln Lys Asp Thr Pro Gln Glu Met Glu Gln Thr Arg Ser Ala Val 
            660                 665                 670


Asp Glu Asp Arg Lys Met Tyr Leu Gln Ala Ala Ile Val Arg Ile Met 
        675                 680                 685


Lys Ala Arg Lys Val Leu Arg His Asn Ala Leu Ile Gln Glu Val Ile 
    690                 695                 700


Ser Gln Ser Arg Ala Arg Phe Asn Pro Ser Ile Ser Met Ile Lys Lys 
705                 710                 715                 720


Cys Ile Glu Val Leu Ile Asp Lys Gln Tyr Ile Glu Arg Ser Gln Ala 
                725                 730                 735


Ser Ala Asp Glu Tyr Ser Tyr Val Ala 
            740                 745


<210>  6426
<211>  2931
<212>  DNA
<213>  Homo sapiens

<400>  6426
attgctttcc gggtggcggg ggggatttgg cagcagcgga agaaggagac cggagggtgt     60

gtgttgggca aagccggagg cagaggagga cgattgtttt acggatcccg tgatcggccc    120

gtccttctcc cctttccccc cctccctacc gcccctgtcc cgccggggag cggcggcggc    180

cttggacttt gctgtctttc ctcgcggaga cagatttcaa cactacactt gcacaatgtc    240

tttgaaacca agagtagtag attttgatga aacatggaac aaacttttga cgacaataaa    300

agccgtggtc atgttggaat acgtcgaaag agcaacatgg aatgaccgtt tctcagatat    360

ctatgcttta tgtgtggcct atcctgaacc ccttggagaa agactttata cagaaactaa    420

gatttttttg gaaaatcatg ttcggcattt gcataagaga gttttggagt cagaagaaca    480

agtacttgtt atgtatcata ggtactggga agaatacagc aagggtgcag actatatgga    540

ctgcttatat aggtatctca acacccagtt tattaaaaag aataaattaa cagaagcgga    600

ccttcagtat ggctatggtg gtgtagatat gaatgaacca cttatggaaa taggagagct    660

agcattggat atgtggagga aattgatggt tgaaccactt caggccatcc ttatccgaat    720

gctgctccga gaaatcaaaa atgatcgtgg tggagaagac ccaaaccaga aagtaatcca    780

tggggttatt aactcctttg ttcatgttga acagtataag aaaaaattcc ccttaaagtt    840

ttatcaggaa atttttgagt ctccctttct gactgaaaca ggagagtatt acaaacaaga    900

agcttcaaat ttattacaag aatcaaactg ctcacagtat atggaaaagg ttctaggtag    960

attaaaagat gaagaaattc gatgtcgaaa atacctacat ccaagttcat atactaaggt   1020

gattcatgaa tgtcaacaac gaatggtagc agaccactta cagtttttac atgcagaatg   1080

tcataatata attcgacaag agaaaaaaaa tgacatggca aatatgtacg tcttactccg   1140

tgctgtgtcc actggtttac ctcatatgat tcaggagctg caaaaccaca tccatgatga   1200

gggccttcga gcaaccagca accttactca ggaaaacatg ccaacactat ttgtggagtc   1260

agttttggaa gtgcatggta aatttgttca gcttatcaac actgttttga atggtgatca   1320

gcattttatg agtgcgttgg ataaggccct tacgtcagtt gtaaattaca gagaacctaa   1380

gtctgtttgc aaagcacctg aactgcttgc taagtactgt gacaacttac tgaagaagtc   1440

agcgaaaggg atgacagaga atgaagtgga agacaggctc acgagcttca tcacagtgtt   1500

caaatacatt gatgacaagg acgtctttca aaagttctac gcaagaatgc tggcaaaacg   1560

tttaattcat gggttatcca tgtctatgga ctctgaagaa gccatgatca acaaattaaa   1620

gcaagcctgt ggttatgagt ttaccagcaa gctacatcgg atgtatacag atatgagtgt   1680

cagcgctgat ctcaacaata agttcaacaa ttttatcaaa aaccaagaca cagtaataga   1740

tttgggaatt agttttcaaa tatatgttct acaggctggt gcgtggcctc ttactcaggc   1800

tccttcatct acgtttgcaa ttccccagga attagaaaaa agtgtacaga tgtttgaatt   1860

attttatagc caacatttca gtggaaggaa acttacatgg ttacattatc tgtgtacagg   1920

tgaagttaaa atgaactatt tgggcaaacc atatgtagcc atggttacaa cataccaaat   1980

ggcagttctt cttgccttta acaacagtga aactgtcagt tataaagagc ttcaggacag   2040

cactcagatg aatgaaaagg aactgacaaa aacaatcaaa tcattacttg atgtgaaaat   2100

gattaaccat gattcagaaa aggaagatat tgatgcagaa tcttcgtttt cattaaatat   2160

gaactttagc agtaaaagaa caaaatttaa aattactaca tcaatgcaga aagacacacc   2220

acaagaaatg gagcagacta gaagtgcagt tgatgaggac cggaaaatgt atctccaagc   2280

tgctatagtt cgtatcatga aagcacgaaa agtgcttcgg cacaatgccc ttattcaaga   2340

ggtgattagc cagtcaagag ctaggtttaa tcccagtatc agcatgatta agaagtgtat   2400

tgaagttctg atagacaaac aatacataga acgcagccag gcgtcggcag atgaatacag   2460

ctacgtcgcg tgatgtcgct ctcctccagc gtggtgtgag aagatcattg ccatcaccat   2520

ttggtgtgtt cctgtgggaa aaagcaggac tgtgcctcca taatttggtc atttggcagc   2580

ccctgttttc tgctgtttac aacatcacca gtgccacgtc atgagcgtca aagaaaatgc   2640

ctagagatat ttcaagctca tgtcattatg acatttctta aaactttatt aaaagaatga   2700

gtgaagtatt gctgaaaagt ggaaattcgg ttgggtacca tgctttttct ccccttcacg   2760

tttgcagttg atgtgtcttt tttttttttt ttaatgtatc ttaaaggaca taaaatttaa   2820

aaacttaaat attgtaatat gacagataac ctaataattg tatctacatt aaaatgacaa   2880

acatgatact gctgcttgtc aaataaaaaa aaaataaaga aatagaatgc c            2931


<210>  6427
<211>  745
<212>  PRT
<213>  Homo sapiens

<400>  6427

Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys 
1               5                   10                  15


Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg 
            20                  25                  30


Ala Thr Trp Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala 
        35                  40                  45


Tyr Pro Glu Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe 
    50                  55                  60


Leu Glu Asn His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu 
65                  70                  75                  80


Glu Gln Val Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys 
                85                  90                  95


Gly Ala Asp Tyr Met Asp Cys Leu Tyr Arg Tyr Leu Asn Thr Gln Phe 
            100                 105                 110


Ile Lys Lys Asn Lys Leu Thr Glu Ala Asp Leu Gln Tyr Gly Tyr Gly 
        115                 120                 125


Gly Val Asp Met Asn Glu Pro Leu Met Glu Ile Gly Glu Leu Ala Leu 
    130                 135                 140


Asp Met Trp Arg Lys Leu Met Val Glu Pro Leu Gln Ala Ile Leu Ile 
145                 150                 155                 160


Arg Met Leu Leu Arg Glu Ile Lys Asn Asp Arg Gly Gly Glu Asp Pro 
                165                 170                 175


Asn Gln Lys Val Ile His Gly Val Ile Asn Ser Phe Val His Val Glu 
            180                 185                 190


Gln Tyr Lys Lys Lys Phe Pro Leu Lys Phe Tyr Gln Glu Ile Phe Glu 
        195                 200                 205


Ser Pro Phe Leu Thr Glu Thr Gly Glu Tyr Tyr Lys Gln Glu Ala Ser 
    210                 215                 220


Asn Leu Leu Gln Glu Ser Asn Cys Ser Gln Tyr Met Glu Lys Val Leu 
225                 230                 235                 240


Gly Arg Leu Lys Asp Glu Glu Ile Arg Cys Arg Lys Tyr Leu His Pro 
                245                 250                 255


Ser Ser Tyr Thr Lys Val Ile His Glu Cys Gln Gln Arg Met Val Ala 
            260                 265                 270


Asp His Leu Gln Phe Leu His Ala Glu Cys His Asn Ile Ile Arg Gln 
        275                 280                 285


Glu Lys Lys Asn Asp Met Ala Asn Met Tyr Val Leu Leu Arg Ala Val 
    290                 295                 300


Ser Thr Gly Leu Pro His Met Ile Gln Glu Leu Gln Asn His Ile His 
305                 310                 315                 320


Asp Glu Gly Leu Arg Ala Thr Ser Asn Leu Thr Gln Glu Asn Met Pro 
                325                 330                 335


Thr Leu Phe Val Glu Ser Val Leu Glu Val His Gly Lys Phe Val Gln 
            340                 345                 350


Leu Ile Asn Thr Val Leu Asn Gly Asp Gln His Phe Met Ser Ala Leu 
        355                 360                 365


Asp Lys Ala Leu Thr Ser Val Val Asn Tyr Arg Glu Pro Lys Ser Val 
    370                 375                 380


Cys Lys Ala Pro Glu Leu Leu Ala Lys Tyr Cys Asp Asn Leu Leu Lys 
385                 390                 395                 400


Lys Ser Ala Lys Gly Met Thr Glu Asn Glu Val Glu Asp Arg Leu Thr 
                405                 410                 415


Ser Phe Ile Thr Val Phe Lys Tyr Ile Asp Asp Lys Asp Val Phe Gln 
            420                 425                 430


Lys Phe Tyr Ala Arg Met Leu Ala Lys Arg Leu Ile His Gly Leu Ser 
        435                 440                 445


Met Ser Met Asp Ser Glu Glu Ala Met Ile Asn Lys Leu Lys Gln Ala 
    450                 455                 460


Cys Gly Tyr Glu Phe Thr Ser Lys Leu His Arg Met Tyr Thr Asp Met 
465                 470                 475                 480


Ser Val Ser Ala Asp Leu Asn Asn Lys Phe Asn Asn Phe Ile Lys Asn 
                485                 490                 495


Gln Asp Thr Val Ile Asp Leu Gly Ile Ser Phe Gln Ile Tyr Val Leu 
            500                 505                 510


Gln Ala Gly Ala Trp Pro Leu Thr Gln Ala Pro Ser Ser Thr Phe Ala 
        515                 520                 525


Ile Pro Gln Glu Leu Glu Lys Ser Val Gln Met Phe Glu Leu Phe Tyr 
    530                 535                 540


Ser Gln His Phe Ser Gly Arg Lys Leu Thr Trp Leu His Tyr Leu Cys 
545                 550                 555                 560


Thr Gly Glu Val Lys Met Asn Tyr Leu Gly Lys Pro Tyr Val Ala Met 
                565                 570                 575


Val Thr Thr Tyr Gln Met Ala Val Leu Leu Ala Phe Asn Asn Ser Glu 
            580                 585                 590


Thr Val Ser Tyr Lys Glu Leu Gln Asp Ser Thr Gln Met Asn Glu Lys 
        595                 600                 605


Glu Leu Thr Lys Thr Ile Lys Ser Leu Leu Asp Val Lys Met Ile Asn 
    610                 615                 620


His Asp Ser Glu Lys Glu Asp Ile Asp Ala Glu Ser Ser Phe Ser Leu 
625                 630                 635                 640


Asn Met Asn Phe Ser Ser Lys Arg Thr Lys Phe Lys Ile Thr Thr Ser 
                645                 650                 655


Met Gln Lys Asp Thr Pro Gln Glu Met Glu Gln Thr Arg Ser Ala Val 
            660                 665                 670


Asp Glu Asp Arg Lys Met Tyr Leu Gln Ala Ala Ile Val Arg Ile Met 
        675                 680                 685


Lys Ala Arg Lys Val Leu Arg His Asn Ala Leu Ile Gln Glu Val Ile 
    690                 695                 700


Ser Gln Ser Arg Ala Arg Phe Asn Pro Ser Ile Ser Met Ile Lys Lys 
705                 710                 715                 720


Cys Ile Glu Val Leu Ile Asp Lys Gln Tyr Ile Glu Arg Ser Gln Ala 
                725                 730                 735


Ser Ala Asp Glu Tyr Ser Tyr Val Ala 
            740                 745


<210>  6428
<211>  2832
<212>  DNA
<213>  Homo sapiens

<400>  6428
attgctttcc gggtggcggg ggggatttgg cagcagcgga agaaggagac cggagggtgt     60

gtgttgggca aagccggagg cagaggagga cgattgtttt acggatcccg tgatcggccc    120

gtccttctcc cctttccccc cctccctacc gcccctgtcc cgccggggag cggcggcggc    180

cttggacttt gctgtctttc ctcgcggaga cagatttcaa cactacactt gcacaatgtc    240

tttgaaacca agagtagtag attttgatga aacatggaac aaacttttga cgacaataaa    300

agccgtggtc atgttggaat acgtcgaaag agcaacatgg aatgaccgtt tctcagatat    360

ctatgcttta tgtgtggcct atcctgaacc ccttggagaa agactttata cagaaactaa    420

gatttttttg gaaaatcatg ttcggcattt gcataagaga gttttggagt cagaagaaca    480

agtacttgtt atgtatcata ggtactggga agaatacagc aagggtgcag actatatgga    540

ctgcttatat aggtatctca acacccagtt tattaaaaag aataaattaa cagaagcgga    600

ccttcagtat ggctatggtg gtgtagatat gaatgaacca cttatggaaa taggagagct    660

agcattggat atgtggagga aattgatggt tgaaccactt caggccatcc ttatccgaat    720

gctgctccga gaaatcaaaa atgatcgtgg tggagaagac ccaaaccaga aagtaatcca    780

tggggttatt aactcctttg ttcatgttga acagtataag aaaaaattcc ccttaaagtt    840

ttatcaggaa atttttgagt ctccctttct gactgaaaca ggagagtatt acaaacaaga    900

agcttcaaat ttattacaag aatcaaactg ctcacagtat atggaaaagg ttctaggtag    960

attaaaagat gaagaaattc gatgtcgaaa atacctacat ccaagttcat atactaaggt   1020

gattcatgaa tgtcaacaac gaatggtagc agaccactta cagtttttac atgcagaatg   1080

tcataatata attcgacaag agaaaaaaaa tgacatggca aatatgtacg tcttactccg   1140

tgctgtgtcc actggtttac ctcatatgat tcaggagctg caaaaccaca tccatgatga   1200

gggccttcga gcaaccagca accttactca ggaaaacatg ccaacactat ttgtggagtc   1260

agttttggaa gtgcatggta aatttgttca gcttatcaac actgttttga atggtgatca   1320

gcattttatg agtgcgttgg ataaggccct tacgtcagtt gtaaattaca gagaacctaa   1380

gtctgtttgc aaagcacctg aactgcttgc taagtactgt gacaacttac tgaagaagtc   1440

agcgaaaggg atgacagaga atgaagtgga agacaggctc acgagcttca tcacagtgtt   1500

caaatacatt gatgacaagg acgtctttca aaagttctac gcaagaatgc tggcaaaacg   1560

tttaattcat gggttatcca tgtctatgga ctctgaagaa gccatgatca acaaattaaa   1620

gcaagcctgt ggttatgagt ttaccagcaa gctacatcgg atgtatacag atatgagtgt   1680

cagcgctgat ctcaacaata agttcaacaa ttttatcaaa aaccaagaca cagtaataga   1740

tttgggaatt agttttcaaa tatatgttct acaggctggt gcgtggcctc ttactcaggc   1800

tccttcatct acgtttgcaa ttccccagga attagaaaaa agtgtacaga tgtttgaatt   1860

attttatagc caacatttca gtggaaggaa acttacatgg ttacattatc tgtgtacagg   1920

tgaagttaaa atgaactatt tgggcaaacc atatgtagcc atggttacaa cataccaaat   1980

ggcagttctt cttgccttta acaacagtga aactgtcagt tataaagagc ttcaggacag   2040

cactcagatg aatgaaaagg aactgacaaa aacaatcaaa tcattacttg atgtgaaaat   2100

gattaaccat gattcagaaa aggaagatat tgatgcagaa tcttcgtttt cattaaatat   2160

gaactttagc agtaaaagaa caaaatttaa aattactaca tcaatgcaga aagacacacc   2220

acaagatgcc cttattcaag aggtgattag ccagtcaaga gctaggttta atcccagtat   2280

cagcatgatt aagaagtgta ttgaagttct gatagacaaa caatacatag aacgcagcca   2340

ggcgtcggca gatgaataca gctacgtcgc gtgatgtcgc tctcctccag cgtggtgtga   2400

gaagatcatt gccatcacca tttggtgtgt tcctgtggga aaaagcagga ctgtgcctcc   2460

ataatttggt catttggcag cccctgtttt ctgctgttta caacatcacc agtgccacgt   2520

catgagcgtc aaagaaaatg cctagagata tttcaagctc atgtcattat gacatttctt   2580

aaaactttat taaaagaatg agtgaagtat tgctgaaaag tggaaattcg gttgggtacc   2640

atgctttttc tccccttcac gtttgcagtt gatgtgtctt tttttttttt tttaatgtat   2700

cttaaaggac ataaaattta aaaacttaaa tattgtaata tgacagataa cctaataatt   2760

gtatctacat taaaatgaca aacatgatac tgctgcttgt caaataaaaa aaaaataaag   2820

aaatagaatg cc                                                       2832


<210>  6429
<211>  712
<212>  PRT
<213>  Homo sapiens

<400>  6429

Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys 
1               5                   10                  15


Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg 
            20                  25                  30


Ala Thr Trp Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala 
        35                  40                  45


Tyr Pro Glu Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe 
    50                  55                  60


Leu Glu Asn His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu 
65                  70                  75                  80


Glu Gln Val Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys 
                85                  90                  95


Gly Ala Asp Tyr Met Asp Cys Leu Tyr Arg Tyr Leu Asn Thr Gln Phe 
            100                 105                 110


Ile Lys Lys Asn Lys Leu Thr Glu Ala Asp Leu Gln Tyr Gly Tyr Gly 
        115                 120                 125


Gly Val Asp Met Asn Glu Pro Leu Met Glu Ile Gly Glu Leu Ala Leu 
    130                 135                 140


Asp Met Trp Arg Lys Leu Met Val Glu Pro Leu Gln Ala Ile Leu Ile 
145                 150                 155                 160


Arg Met Leu Leu Arg Glu Ile Lys Asn Asp Arg Gly Gly Glu Asp Pro 
                165                 170                 175


Asn Gln Lys Val Ile His Gly Val Ile Asn Ser Phe Val His Val Glu 
            180                 185                 190


Gln Tyr Lys Lys Lys Phe Pro Leu Lys Phe Tyr Gln Glu Ile Phe Glu 
        195                 200                 205


Ser Pro Phe Leu Thr Glu Thr Gly Glu Tyr Tyr Lys Gln Glu Ala Ser 
    210                 215                 220


Asn Leu Leu Gln Glu Ser Asn Cys Ser Gln Tyr Met Glu Lys Val Leu 
225                 230                 235                 240


Gly Arg Leu Lys Asp Glu Glu Ile Arg Cys Arg Lys Tyr Leu His Pro 
                245                 250                 255


Ser Ser Tyr Thr Lys Val Ile His Glu Cys Gln Gln Arg Met Val Ala 
            260                 265                 270


Asp His Leu Gln Phe Leu His Ala Glu Cys His Asn Ile Ile Arg Gln 
        275                 280                 285


Glu Lys Lys Asn Asp Met Ala Asn Met Tyr Val Leu Leu Arg Ala Val 
    290                 295                 300


Ser Thr Gly Leu Pro His Met Ile Gln Glu Leu Gln Asn His Ile His 
305                 310                 315                 320


Asp Glu Gly Leu Arg Ala Thr Ser Asn Leu Thr Gln Glu Asn Met Pro 
                325                 330                 335


Thr Leu Phe Val Glu Ser Val Leu Glu Val His Gly Lys Phe Val Gln 
            340                 345                 350


Leu Ile Asn Thr Val Leu Asn Gly Asp Gln His Phe Met Ser Ala Leu 
        355                 360                 365


Asp Lys Ala Leu Thr Ser Val Val Asn Tyr Arg Glu Pro Lys Ser Val 
    370                 375                 380


Cys Lys Ala Pro Glu Leu Leu Ala Lys Tyr Cys Asp Asn Leu Leu Lys 
385                 390                 395                 400


Lys Ser Ala Lys Gly Met Thr Glu Asn Glu Val Glu Asp Arg Leu Thr 
                405                 410                 415


Ser Phe Ile Thr Val Phe Lys Tyr Ile Asp Asp Lys Asp Val Phe Gln 
            420                 425                 430


Lys Phe Tyr Ala Arg Met Leu Ala Lys Arg Leu Ile His Gly Leu Ser 
        435                 440                 445


Met Ser Met Asp Ser Glu Glu Ala Met Ile Asn Lys Leu Lys Gln Ala 
    450                 455                 460


Cys Gly Tyr Glu Phe Thr Ser Lys Leu His Arg Met Tyr Thr Asp Met 
465                 470                 475                 480


Ser Val Ser Ala Asp Leu Asn Asn Lys Phe Asn Asn Phe Ile Lys Asn 
                485                 490                 495


Gln Asp Thr Val Ile Asp Leu Gly Ile Ser Phe Gln Ile Tyr Val Leu 
            500                 505                 510


Gln Ala Gly Ala Trp Pro Leu Thr Gln Ala Pro Ser Ser Thr Phe Ala 
        515                 520                 525


Ile Pro Gln Glu Leu Glu Lys Ser Val Gln Met Phe Glu Leu Phe Tyr 
    530                 535                 540


Ser Gln His Phe Ser Gly Arg Lys Leu Thr Trp Leu His Tyr Leu Cys 
545                 550                 555                 560


Thr Gly Glu Val Lys Met Asn Tyr Leu Gly Lys Pro Tyr Val Ala Met 
                565                 570                 575


Val Thr Thr Tyr Gln Met Ala Val Leu Leu Ala Phe Asn Asn Ser Glu 
            580                 585                 590


Thr Val Ser Tyr Lys Glu Leu Gln Asp Ser Thr Gln Met Asn Glu Lys 
        595                 600                 605


Glu Leu Thr Lys Thr Ile Lys Ser Leu Leu Asp Val Lys Met Ile Asn 
    610                 615                 620


His Asp Ser Glu Lys Glu Asp Ile Asp Ala Glu Ser Ser Phe Ser Leu 
625                 630                 635                 640


Asn Met Asn Phe Ser Ser Lys Arg Thr Lys Phe Lys Ile Thr Thr Ser 
                645                 650                 655


Met Gln Lys Asp Thr Pro Gln Asp Ala Leu Ile Gln Glu Val Ile Ser 
            660                 665                 670


Gln Ser Arg Ala Arg Phe Asn Pro Ser Ile Ser Met Ile Lys Lys Cys 
        675                 680                 685


Ile Glu Val Leu Ile Asp Lys Gln Tyr Ile Glu Arg Ser Gln Ala Ser 
    690                 695                 700


Ala Asp Glu Tyr Ser Tyr Val Ala 
705                 710


<210>  6430
<211>  779
<212>  DNA
<213>  Homo sapiens

<400>  6430
ggggcagcta aggaaaagat aagcacttta ggtagagaaa atagtaaggg taaaggcaag     60

tgtatgaatc aggctgatgt gttcagtgat ctctaagcag agagaagttc ctagattatg    120

atgtcacagt agggagtacc aggaggagag gaagcttggg tgccatgttg cagttgagcc    180

caaactgaat gctgtctgta gaaggaaaca acaaactttg tactttatgt acagagtaac    240

atggtcaact ttttggctta ggtaggttat ttttgtgtct ttgataaggg caagatctga    300

gattctgatc ttgaagtcaa gaactttgtt ttgtccactg tatcctcaga gcttggaatg    360

gtgcctggca aggaatttca acactacact tgcacaatgt ctttgaaacc aagagtagta    420

gattttgatg aaacatggaa caaacttttg acgacaataa aagccgtggt catgttggaa    480

tacgtcgaaa gagcaacatg gaatgaccgt ttctcagata tctatgcttt atgtgtggcc    540

tatcctgaac cccttggaga aagactttat acagaaacta agattttttt ggaaaatcat    600

gttcggcatt tgcataagag agttttggag tcagaagaac aagtacttgt tatgtatcat    660

aggtactggg aagaatacag caagggtgca gactatatgg actgcttata tagtggactt    720

tatcttgact ttcccaagaa gagtctggga agtagcaaac gagattatag aaattctga     779


<210>  6431
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  6431

Met Val Pro Gly Lys Glu Phe Gln His Tyr Thr Cys Thr Met Ser Leu 
1               5                   10                  15


Lys Pro Arg Val Val Asp Phe Asp Glu Thr Trp Asn Lys Leu Leu Thr 
            20                  25                  30


Thr Ile Lys Ala Val Val Met Leu Glu Tyr Val Glu Arg Ala Thr Trp 
        35                  40                  45


Asn Asp Arg Phe Ser Asp Ile Tyr Ala Leu Cys Val Ala Tyr Pro Glu 
    50                  55                  60


Pro Leu Gly Glu Arg Leu Tyr Thr Glu Thr Lys Ile Phe Leu Glu Asn 
65                  70                  75                  80


His Val Arg His Leu His Lys Arg Val Leu Glu Ser Glu Glu Gln Val 
                85                  90                  95


Leu Val Met Tyr His Arg Tyr Trp Glu Glu Tyr Ser Lys Gly Ala Asp 
            100                 105                 110


Tyr Met Asp Cys Leu Tyr Ser Gly Leu Tyr Leu Asp Phe Pro Lys Lys 
        115                 120                 125


Ser Leu Gly Ser Ser Lys Arg Asp Tyr Arg Asn 
    130                 135


<210>  6432
<211>  675
<212>  DNA
<213>  Homo sapiens

<400>  6432
ggggcagcta aggaaaagat aagcacttta ggtagagaaa atagtaaggg taaaggcaag     60

tgtatgaatc aggctgatgt gttcagtgat ctctaagcag agagaagttc ctagattatg    120

atgtcacagt agggagtacc aggaggagag gaagcttggg tgccatgttg cagttgagcc    180

caaactgaat gctgtctgta gaaggaaaca acaaactttg tactttatgt acagagtaac    240

atggtcaact ttttggctta gatttcaaca ctacacttgc acaatgtctt tgaaaccaag    300

agtagtagat tttgatgaaa catggaacaa acttttgacg acaataaaag ccgtggtcat    360

gttggaatac gtcgaaagag caacatggaa tgaccgtttc tcattcatta tctttacctt    420

ggagacactt ggtggtggtc atcgtactga taagatggca tagctttatc atggaacagt    480

ctggagtata accaccagga ggtcctgacc tctgtgttgc tctggtgtca ttgttcctgt    540

ggacaaatga gctgttacct ccaaaatgcc ttgtcacagt agttggaggc agcatatgaa    600

acacctagtt cccagaatca taatctaata ccgtgtctgg ccccaaagtt ataaatgggc    660

tttgccttaa gtctt                                                     675


<210>  6433
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  6433

Met Tyr Arg Val Thr Trp Ser Thr Phe Trp Leu Arg Phe Gln His Tyr 
1               5                   10                  15


Thr Cys Thr Met Ser Leu Lys Pro Arg Val Val Asp Phe Asp Glu Thr 
            20                  25                  30


Trp Asn Lys Leu Leu Thr Thr Ile Lys Ala Val Val Met Leu Glu Tyr 
        35                  40                  45


Val Glu Arg Ala Thr Trp Asn Asp Arg Phe Ser Phe Ile Ile Phe Thr 
    50                  55                  60


Leu Glu Thr Leu Gly Gly Gly His Arg Thr Asp Lys Met Ala 
65                  70                  75


<210>  6434
<211>  617
<212>  DNA
<213>  Homo sapiens

<400>  6434
accgcgtcct cccgccccgt cctcccctcc cccacgccgg gacggcctcc cgggggaggc     60

cccgaggaaa aaaatccagg ctcgaactcc gccccctgcc ggccgccagc aggagtgaag    120

cgccacaatc caacaatgaa atggaaccgg ggaggggcgg cgggaaggtt atagtgccat    180

catgtggata ctttgttttc ttcaaataaa atgtaacctt tttataacag agactagaaa    240

acccagccat cccaacaccc aggatagagg cactctccat tcctgattgt tccaaggctc    300

aagtggtcag aaatgactgg gaagaaggga gaaaaactca ggtggcaaag gacatggacg    360

aaaacccatg gcgacatgga aagaaaaccc tgtgatatag agaggaaaag cacaggacag    420

cttattgggg agaatggaac tcttctgtat cctgattgcg gtgatggcca cgcatggctg    480

taacactaca cttgcacaat gtctttgaaa ccaagagtag tagattttga tgaaacatgg    540

aacaaacttt tgacgacaat aaaagccgtg gtcatgttgg aatacgtcga aagagcaaca    600

tggaatgacc gtttctc                                                   617


<210>  6435
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  6435

Met Trp Ile Leu Cys Phe Leu Gln Ile Lys Cys Asn Leu Phe Ile Thr 
1               5                   10                  15


Glu Thr Arg Lys Pro Ser His Pro Asn Thr Gln Asp Arg Gly Thr Leu 
            20                  25                  30


His Ser 



<210>  6436
<211>  510
<212>  DNA
<213>  Homo sapiens

<400>  6436
ctgccgaccc cggaccaaaa gtagcgctgc agccgaccga accgcgtcct cccgccccgt     60

cctcccctcc cccacgccgg gacggcctcc cgggggaggc cccgaggaaa aaaatccagg    120

ctcgaactcc gccccctgcc ggccgccagc aggagtgaag cgccacaatc caacaatgaa    180

atggaaccgg ggaggggcgg cgggaaggtt atagtgccat catgtggata ctttgttttc    240

ttcaaataaa atgtaacctt tttataacag agactagaaa acccagccat cccaacaccc    300

aggctgtgca aagaaattgg ggccaaacgt ttttttgcca tgttctgaaa agaggcactc    360

tccattcctg attgttccaa ggctcaagtg gtcagaaatg actgggaaga agggagaaaa    420

actcaggtgg caaaggacat ggacgaaaac ccatggcgac atggaaagaa aaccctgtga    480

tatagagagg aaaagcacag gacagcttat                                     510


<210>  6437
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  6437

Met Trp Ile Leu Cys Phe Leu Gln Ile Lys Cys Asn Leu Phe Ile Thr 
1               5                   10                  15


Glu Thr Arg Lys Pro Ser His Pro Asn Thr Gln Ala Val Gln Arg Asn 
            20                  25                  30


Trp Gly Gln Thr Phe Phe Cys His Val Leu Lys Arg Gly Thr Leu His 
        35                  40                  45


Ser 



<210>  6438
<211>  788
<212>  DNA
<213>  Homo sapiens

<400>  6438
atccaatgac ttgtcagcca gagtaacggc tgttgtcagg tcttcagggt ctcgaggtcg     60

gtttcttcct aacgccgcca accccaagct aaggtagaca tgatcgccaa ggcagctgat    120

tgtcccaagg aataagtatg agcaatgagc acagagggaa aatcatgaaa catctgagga    180

ccatgagaac tgctaaaaca atacgtagaa ctagctatac cagagaaagt caagtgaatg    240

gatcagacaa taagaattga aaataagctt aatagagctt cagagaaaga agggagaatg    300

ttggaaacac aaagcacaaa caagcatttg tgaattggat gttgacaaat attaatgaaa    360

taactcaatg gatgggttga atatagctgg acagttcact catgaaccgg aagattagag    420

caaggaagga actaagaaat ggaaagcatg aaaggagagt taagaaatgt ggaaggtaga    480

agcataaata tttttctaat ggaaattcca gaaggggaaa aaaagaacat gtgaaagaat    540

tattgctgag aatttcccag aattgaagac atactttaga atgaaaaagg ccaactctaa    600

ctttgggatt tctagcttca gagaaatgaa aatttagaat gaccaagggg agtgcacagg    660

attttttggg cagtgaaact attctgcatg atactataat ggtggatgca tgctattaca    720

catttgtcaa aacccattga atgtacatca ctgagaatga agcctaatgt atgcactttg    780

gatgatta                                                             788


<210>  6439
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  6439

Met Ser Asn Glu His Arg Gly Lys Ile Met Lys His Leu Arg Thr Met 
1               5                   10                  15


Arg Thr Ala Lys Thr Ile Arg Arg Thr Ser Tyr Thr Arg Glu Ser Gln 
            20                  25                  30


Val Asn Gly Ser Asp Asn Lys Asn 
        35                  40


<210>  6440
<211>  596
<212>  DNA
<213>  Homo sapiens

<400>  6440
atttcattgt tggattgtgg cgcttcactc ctgctggcgg ccggcagggg gcggagttcg     60

agcctggatt tttttcctcg gggcctcccc cgggaggccg tcccggcgtg ggggagggga    120

ggacggggcg ggaggacgcg gttcggtcgg ctgcagcgct acttttggtc cggggtcggc    180

agggaggccg cggctaccgc atcacagctg acgtgaggac tacgtggggc cgctgccggc    240

tccgggttgc tgggcggcgg cgccgctgct gagcggcggt cgggctcgcc gtctccacct    300

cctcgcgtcc gtaatcagtg acgaggtccg ctacgtaaat ccctttgcgg cggacaaatg    360

accatggaaa cagttgaatc ccagcatgat ggaagtataa cagcttcttt gacagagagc    420

aagtctgctc atgtgcagac tcagactggc caaaattcaa tccctgcttt agctcagagc    480

ttctgctaat caagaatata ctatgaaaat catcagagac ctagcaactg ttgagcttgg    540

ttttggctgt caggcccctg ttctgctgat ggattgaggt gaggtgcagg tacacc        596


<210>  6441
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  6441

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Ser Phe Cys 
        35                  40


<210>  6442
<211>  731
<212>  DNA
<213>  Homo sapiens

<400>  6442
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggat aaataaagaa aacaggaaag    360

gaggaaagca ttgattacaa atatcttaac aatgagcaaa tgtgcaagga aaaaatatat    420

taagacaaat ccaagacaaa tgaccatgga aacagttgaa tcccagcatg atggaagtat    480

aacagcttct ttgacagaga gcaagtctgc tcatgtgcag actcagactg gccaaaattc    540

aatccctgct ttagctcagg taggcaatag gcaggcaccg ttgaaagtca aaatatatgg    600

aaatgagaat taggtgcaga ttctgttttc ttgccattga tcttaaattt tccatgttcc    660

ctggttatca gccattcttg cttatttgat tgtgaagaaa agatacgtgt tgtaattagc    720

cttgcatttt a                                                         731


<210>  6443
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  6443

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Gly Asn Arg Gln Ala Pro Leu 
    50                  55                  60


Lys Val Lys Ile Tyr Gly Asn Glu Asn 
65                  70


<210>  6444
<211>  966
<212>  DNA
<213>  Homo sapiens

<400>  6444
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca gtgcacaatg tgtaaggagt    480

ccctcggaat aaagcagccc tggcatgcca tcggggattg aagtaggaac gatttaacaa    540

gggatacttg gaaatgttgt catgtgcgag ttgtaaattt tcttttttaa tctggtggaa    600

aattggaatg gcatttctct gttttgccca gctatgccaa aaatcttctt ggtcccacat    660

aggcctagga aggatgtaga tggcaatcac aaaacaaaca aaaaatgagc aaacaaatag    720

aagacctcaa gcaacatttt ctcttgttaa taggttagca acctcatatt tgtatattaa    780

agagatctgc attatgttag gttgatttca tataatttca gctaagtaga tctagtttaa    840

ggtcagtgtt ttattgaatc ttgtatttta gcttcagtat attaatttcc ttagctgagg    900

gactcctact gaaggagaaa agtgttcctg ttaaaatttt gaaataaaag tttctgtttt    960

actgta                                                               966


<210>  6445
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  6445

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Cys Thr Met Cys Lys Glu Ser Leu 
        35                  40                  45


Gly Ile Lys Gln Pro Trp His Ala Ile Gly Asp 
    50                  55


<210>  6446
<211>  1149
<212>  DNA
<213>  Homo sapiens

<400>  6446
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacagt atgtatgctg caattcgata    600

tgatacagtg ctagctttaa gtcttctcta gttatattga agcaactcag gttttggcat    660

taaattgttc cattttaaaa tgcatcatta atacctaaac tgtatcatag aatgaaagta    720

tatgttaaaa agtgagatct ttgtattgac agctgtcata taattttgaa aagtaaaaat    780

tttgactgcc gaatatagaa gaaaattttg gggtaaaaag gagaattttt cctatttaca    840

tgtttatatt aatctctagt aaaacattgt ttttgttgtc tttatgatgc atgcgaacat    900

aaatgtctgt atttcattct tgttggcttt tgttacccac aattacatac tattcttact    960

aatctgagag ttttctaaag tatgttttca atgtttcact actctctact ctgttaattt   1020

gtgctacagt ttttcctaaa agagaatgga aaaatgattt aattttttaa actgtagcaa   1080

ttggatagat aattttattt gaaattttac acactgaaag ctctaaataa acagatacat   1140

tcacattca                                                           1149


<210>  6447
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  6447

Met Asn Cys Pro Leu Met Cys Leu Val Phe Pro Arg Leu Lys Lys Arg 
1               5                   10                  15


Asp Gln Arg Lys Lys Glu His His Leu Val Leu Leu Pro Trp Gln Tyr 
            20                  25                  30


Gln Leu Ala Tyr Ile Arg Leu Ala Arg Gly Asn Thr Val Cys Met Leu 
        35                  40                  45


Gln Phe Asp Met Ile Gln Cys 
    50                  55


<210>  6448
<211>  1273
<212>  DNA
<213>  Homo sapiens

<400>  6448
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca ggtagcagca attgcagaga    480

cagatgaatc tgcagaatca gaaggtgtaa ttgattctca taaacgtaga gaaatccttt    540

cacgaagacc ctcttatagg aaaatactga atgaactgtc ctctgatgtg cctggtgttc    600

ccaagattga agaagagaga tcagaggaag aaggaacacc acctagtatt gctaccatgg    660

cagtaccaac tagcatatat cagactagca cggggcaata cagtatgtat gctgcaattc    720

gatatgatac agtgctagct ttaagtcttc tctagttata ttgaagcaac tcaggttttg    780

gcattaaatt gttccatttt aaaatgcatc attaatacct aaactgtatc atagaatgaa    840

agtatatgtt aaaaagtgag atctttgtat tgacagctgt catataattt tgaaaagtaa    900

aaattttgac tgccgaatat agaagaaaat tttggggtaa aaaggagaat ttttcctatt    960

tacatgttta tattaatctc tagtaaaaca ttgtttttgt tgtctttatg atgcatgcga   1020

acataaatgt ctgtatttca ttcttgttgg cttttgttac ccacaattac atactattct   1080

tactaatctg agagttttct aaagtatgtt ttcaatgttt cactactctc tactctgtta   1140

atttgtgcta cagtttttcc taaaagagaa tggaaaaatg atttaatttt ttaaactgta   1200

gcaattggat agataatttt atttgaaatt ttacacactg aaagctctaa ataaacagat   1260

acattcacat tca                                                      1273


<210>  6449
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  6449

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
        35                  40                  45


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
    50                  55                  60


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
65                  70                  75                  80


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
                85                  90                  95


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
            100                 105                 110


Tyr Gln Thr Ser Thr Gly Gln Tyr Ser Met Tyr Ala Ala Ile Arg Tyr 
        115                 120                 125


Asp Thr Val Leu Ala Leu Ser Leu Leu 
    130                 135


<210>  6450
<211>  799
<212>  DNA
<213>  Homo sapiens

<400>  6450
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca ggtagcagca attgcagaga    480

cagatgaatc tgcagaatca gaaggtgtaa ttgattctca taaacgtaga gaaatccttt    540

cacgaagacc ctcttatagg aaaatactga atgaactgtc ctctgatgtg cctggtgttc    600

ccaagattga agaagagaga tcagaggaag aaggaacacc acctagtatt gctaccatgg    660

cagtaccaac tagcatatat cagactagca cggggcaata cattgctata gcccaaggtg    720

gaacaatcca gatttctaac ccaggatctg atggtgttca gggactgcag gcattaacaa    780

tgacaaattc aggagctcc                                                 799


<210>  6451
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  6451

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
        35                  40                  45


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
    50                  55                  60


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
65                  70                  75                  80


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
                85                  90                  95


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
            100                 105                 110


Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr 
        115                 120                 125


Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln Ala 
    130                 135                 140


Leu Thr Met Thr Asn Ser Gly 
145                 150


<210>  6452
<211>  1356
<212>  DNA
<213>  Homo sapiens

<400>  6452
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgcccggga gtgtcgcagg aagaagaaag aatatgtcaa    780

atgtcttgaa aatcgtgtgg ctgtgcttga aaaccaaaac aagactctca ttgaggaact    840

caaggccctc aaagatcttt attgccataa agtagagtaa ctgtctttga cttggacctt    900

gtttactcta atcaaggcag gagatgcagc agtcctactt attgccatgt ggacttgtgg    960

gaaggacacg tgtgaccctt aagaatccag tttggattag tgtttgaaat tgaattggga   1020

atgttgttcc aggatgtgga atgcagccgt gatcacactt accgagctta ctttgatctg   1080

tttgtcaata gcatgcaaaa aatgctttgt ttgccctttg cttctgcttt ttttcaggga   1140

agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta aaatgtctgg agagccgagt   1200

tgcagtgctg gaagtccaga acaagaagct tatagaggaa cttgaaacct tgaaagacat   1260

ttgttctccc aaaacagatt actagaaata tttaactatg aactgaaggc agcatgtata   1320

gttgcttttg aaggaataca atatatagct ggcaag                             1356


<210>  6453
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6453

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn 
                85                  90                  95


Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His 
            100                 105                 110


Lys Val Glu 
        115


<210>  6454
<211>  1115
<212>  DNA
<213>  Homo sapiens

<400>  6454
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    540

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    600

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg    660

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg    720

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa    780

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt    840

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa    900

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt    960

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1020

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1080

ttgcttttga aggaatacaa tatatagctg gcaag                              1115


<210>  6455
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6455

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6456
<211>  954
<212>  DNA
<213>  Homo sapiens

<400>  6456
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa    780

atgtctggag agccgagttg cagtgctgga agtccagaac aagaagctta tagaggaact    840

tgaaaccttg aaagacattt gttctcccaa aacagattac tagaaatatt taactatgaa    900

ctgaaggcag catgtatagt tgcttttgaa ggaatacaat atatagctgg caag          954


<210>  6457
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  6457

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn 
                85                  90                  95


Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro 
            100                 105                 110


Lys Thr Asp Tyr 
        115


<210>  6458
<211>  1239
<212>  DNA
<213>  Homo sapiens

<400>  6458
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca gctgccactg gtgacatgcc    480

aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga tggctgcatc    540

gcccggaagt ttgcacagtc cccagcagct ggcagaagaa gcaacacgca aacgagagct    600

gaggctaatg aaaaacaggg aagctgcccg ggagtgtcgc aggaagaaga aagaatatgt    660

caaatgtctt gaaaatcgtg tggctgtgct tgaaaaccaa aacaagactc tcattgagga    720

actcaaggcc ctcaaagatc tttattgcca taaagtagag taactgtctt tgacttggac    780

cttgtttact ctaatcaagg caggagatgc agcagtccta cttattgcca tgtggacttg    840

tgggaaggac acgtgtgacc cttaagaatc cagtttggat tagtgtttga aattgaattg    900

ggaatgttgt tccaggatgt ggaatgcagc cgtgatcaca cttaccgagc ttactttgat    960

ctgtttgtca atagcatgca aaaaatgctt tgtttgccct ttgcttctgc tttttttcag   1020

ggaagctgcc aaagaatgtc gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg   1080

agttgcagtg ctggaagtcc agaacaagaa gcttatagag gaacttgaaa ccttgaaaga   1140

catttgttct cccaaaacag attactagaa atatttaact atgaactgaa ggcagcatgt   1200

atagttgctt ttgaaggaat acaatatata gctggcaag                          1239


<210>  6459
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6459

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6460
<211>  776
<212>  DNA
<213>  Homo sapiens

<400>  6460
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg gaagctgcca aagaatgtcg acgtcgaaag aaagaatatg taaaatgtct    360

ggagagccga gttgcagtgc tggaagtcca gaacaagaag cttatagagg aacttgaaac    420

cttgaaagac atttgttctc ccaaaacaga ttactagaaa tatttaacta tgaactgaag    480

gcagcatgta tagttgcttt tgaaggaata caatatatag ctggcaagaa tggtggcttc    540

ttttctttgt atcattcatc ttcttcttta atcacttaac attcctaaaa tgcttcactg    600

tacgtagtta agtcgtagct ataacttcaa attttttaaa agagacaaac tgtaaaaaat    660

gtgtgtattc ttaaaatgca atatttgtaa ggcttgttcc aatgccacat acttgcagct    720

cccattctat gtgtcatcaa tagtgtccta tgcaataaaa ttatttgcag gtcttt        776


<210>  6461
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  6461

Met Cys Val Phe Leu Lys Cys Asn Ile Cys Lys Ala Cys Ser Asn Ala 
1               5                   10                  15


Thr Tyr Leu Gln Leu Pro Phe Tyr Val Ser Ser Ile Val Ser Tyr Ala 
            20                  25                  30


Ile Lys Leu Phe Ala Gly 
        35


<210>  6462
<211>  1604
<212>  DNA
<213>  Homo sapiens

<400>  6462
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgcccggga gtgtcgcagg aagaagaaag aatatgtcaa    780

atgtcttgaa aatcgtgtgg ctgtgcttga aaaccaaaac aagactctca ttgaggaact    840

caaggccctc aaagatcttt attgccataa agtagagtaa ctgtctttga cttggacctt    900

gtttactcta atcaaggcag gagatgcagc agtcctactt attgccatgt ggacttgtgg    960

gaaggacacg tgtgaccctt aagaatccag tttggattag tgtttgaaat tgaattggga   1020

atgttgttcc aggatgtgga atgcagccgt gatcacactt accgagctta ctttgatctg   1080

tttgtcaata gcatgcaaaa aatgctttgt ttgccctttg cttctgcttt ttttcaggga   1140

agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta aaatgtctgg agagccgagt   1200

tgcagtgctg gaagtccaga acaagaagct tatagaggaa cttgaaacct tgaaagacat   1260

ttgttctccc aaaacagatt actagaaata tttaactatg aactgaaggc agcatgtata   1320

gttgcttttg aaggaataca atatatagct ggcaagaatg gtggcttctt ttctttgtat   1380

cattcatctt cttctttaat cacttaacat tcctaaaatg cttcactgta cgtagttaag   1440

tcgtagctat aacttcaaat tttttaaaag agacaaactg taaaaaatgt gtgtattctt   1500

aaaatgcaat atttgtaagg cttgttccaa tgccacatac ttgcagctcc cattctatgt   1560

gtcatcaata gtgtcctatg caataaaatt atttgcaggt cttt                    1604


<210>  6463
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6463

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn 
                85                  90                  95


Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His 
            100                 105                 110


Lys Val Glu 
        115


<210>  6464
<211>  1202
<212>  DNA
<213>  Homo sapiens

<400>  6464
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa    780

atgtctggag agccgagttg cagtgctgga agtccagaac aagaagctta tagaggaact    840

tgaaaccttg aaagacattt gttctcccaa aacagattac tagaaatatt taactatgaa    900

ctgaaggcag catgtatagt tgcttttgaa ggaatacaat atatagctgg caagaatggt    960

ggcttctttt ctttgtatca ttcatcttct tctttaatca cttaacattc ctaaaatgct   1020

tcactgtacg tagttaagtc gtagctataa cttcaaattt tttaaaagag acaaactgta   1080

aaaaatgtgt gtattcttaa aatgcaatat ttgtaaggct tgttccaatg ccacatactt   1140

gcagctccca ttctatgtgt catcaatagt gtcctatgca ataaaattat ttgcaggtct   1200

tt                                                                  1202


<210>  6465
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  6465

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn 
                85                  90                  95


Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro 
            100                 105                 110


Lys Thr Asp Tyr 
        115


<210>  6466
<211>  1363
<212>  DNA
<213>  Homo sapiens

<400>  6466
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    540

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    600

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg    660

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg    720

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa    780

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt    840

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa    900

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt    960

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1020

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1080

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1140

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1200

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1260

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1320

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc ttt                     1363


<210>  6467
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6467

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6468
<211>  961
<212>  DNA
<213>  Homo sapiens

<400>  6468
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    540

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    600

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac    660

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg    720

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt    780

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa    840

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg    900

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt    960

t                                                                    961


<210>  6469
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  6469

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile 
65                  70                  75                  80


Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                85                  90                  95


<210>  6470
<211>  1487
<212>  DNA
<213>  Homo sapiens

<400>  6470
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca gctgccactg gtgacatgcc    480

aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga tggctgcatc    540

gcccggaagt ttgcacagtc cccagcagct ggcagaagaa gcaacacgca aacgagagct    600

gaggctaatg aaaaacaggg aagctgcccg ggagtgtcgc aggaagaaga aagaatatgt    660

caaatgtctt gaaaatcgtg tggctgtgct tgaaaaccaa aacaagactc tcattgagga    720

actcaaggcc ctcaaagatc tttattgcca taaagtagag taactgtctt tgacttggac    780

cttgtttact ctaatcaagg caggagatgc agcagtccta cttattgcca tgtggacttg    840

tgggaaggac acgtgtgacc cttaagaatc cagtttggat tagtgtttga aattgaattg    900

ggaatgttgt tccaggatgt ggaatgcagc cgtgatcaca cttaccgagc ttactttgat    960

ctgtttgtca atagcatgca aaaaatgctt tgtttgccct ttgcttctgc tttttttcag   1020

ggaagctgcc aaagaatgtc gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg   1080

agttgcagtg ctggaagtcc agaacaagaa gcttatagag gaacttgaaa ccttgaaaga   1140

catttgttct cccaaaacag attactagaa atatttaact atgaactgaa ggcagcatgt   1200

atagttgctt ttgaaggaat acaatatata gctggcaaga atggtggctt cttttctttg   1260

tatcattcat cttcttcttt aatcacttaa cattcctaaa atgcttcact gtacgtagtt   1320

aagtcgtagc tataacttca aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt   1380

cttaaaatgc aatatttgta aggcttgttc caatgccaca tacttgcagc tcccattcta   1440

tgtgtcatca atagtgtcct atgcaataaa attatttgca ggtcttt                 1487


<210>  6471
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6471

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6472
<211>  1121
<212>  DNA
<213>  Homo sapiens

<400>  6472
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg gaagctgcca aagaatgtcg acgtcgaaag aaagaatatg taaaatgtct    360

ggagagccga gttgcagtgc tggaagtcca gaacaagaag cttatagagg aacttgaaac    420

cttgaaagac atttgttctc ccaaaacaga ttactagaaa tatttaacta tgaactgaag    480

gcagcatgta tagttgcttt tgaaggaata caatatatag ctggcaagaa tggtggcttc    540

ttttctttgt atcattcatc ttcttcttta atcacttaac attcctaaaa tgcttcactg    600

tacgtagtta agtcgtagct ataacttcaa attttttaaa agagacaaac tgtaaaaaat    660

gtgtgtattc ttaaaatgca atatttgtaa ggcttgttcc aatgccacat acttgcagct    720

cccattctat gtgtcatcaa tagtgtccta tgcaataaaa ttatttgcag gtctttaaat    780

cattttagga aaggatgatc aaaaataatg catccagcag tacaataaaa gtaaaccaca    840

aaaaaatacc tcaggaaaga atagaaagaa agtctatcta atgacatgcc tatatgagaa    900

gaatagccta gatatgaata tatggcattt gcagattttt atattagttg ctttgttaaa    960

aaaaaaaaga ttgtattgct gtccttgaat gccatagtca aagagagttt ttaatagaac   1020

catgttggtt gcactttgta gtgtttggtg ctcatttaaa tatctgaaca tttactacag   1080

tttttaactc tactgtgtaa tataaaagat cttgcagaag t                       1121


<210>  6473
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  6473

Met Cys Val Phe Leu Lys Cys Asn Ile Cys Lys Ala Cys Ser Asn Ala 
1               5                   10                  15


Thr Tyr Leu Gln Leu Pro Phe Tyr Val Ser Ser Ile Val Ser Tyr Ala 
            20                  25                  30


Ile Lys Leu Phe Ala Gly Leu 
        35


<210>  6474
<211>  1832
<212>  DNA
<213>  Homo sapiens

<400>  6474
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca gctgccactg gtgacatgcc    480

aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga tggctgcatc    540

gcccggaagt ttgcacagtc cccagcagct ggcagaagaa gcaacacgca aacgagagct    600

gaggctaatg aaaaacaggg aagctgcccg ggagtgtcgc aggaagaaga aagaatatgt    660

caaatgtctt gaaaatcgtg tggctgtgct tgaaaaccaa aacaagactc tcattgagga    720

actcaaggcc ctcaaagatc tttattgcca taaagtagag taactgtctt tgacttggac    780

cttgtttact ctaatcaagg caggagatgc agcagtccta cttattgcca tgtggacttg    840

tgggaaggac acgtgtgacc cttaagaatc cagtttggat tagtgtttga aattgaattg    900

ggaatgttgt tccaggatgt ggaatgcagc cgtgatcaca cttaccgagc ttactttgat    960

ctgtttgtca atagcatgca aaaaatgctt tgtttgccct ttgcttctgc tttttttcag   1020

ggaagctgcc aaagaatgtc gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg   1080

agttgcagtg ctggaagtcc agaacaagaa gcttatagag gaacttgaaa ccttgaaaga   1140

catttgttct cccaaaacag attactagaa atatttaact atgaactgaa ggcagcatgt   1200

atagttgctt ttgaaggaat acaatatata gctggcaaga atggtggctt cttttctttg   1260

tatcattcat cttcttcttt aatcacttaa cattcctaaa atgcttcact gtacgtagtt   1320

aagtcgtagc tataacttca aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt   1380

cttaaaatgc aatatttgta aggcttgttc caatgccaca tacttgcagc tcccattcta   1440

tgtgtcatca atagtgtcct atgcaataaa attatttgca ggtctttaaa tcattttagg   1500

aaaggatgat caaaaataat gcatccagca gtacaataaa agtaaaccac aaaaaaatac   1560

ctcaggaaag aatagaaaga aagtctatct aatgacatgc ctatatgaga agaatagcct   1620

agatatgaat atatggcatt tgcagatttt tatattagtt gctttgttaa aaaaaaaaag   1680

attgtattgc tgtccttgaa tgccatagtc aaagagagtt tttaatagaa ccatgttggt   1740

tgcactttgt agtgtttggt gctcatttaa atatctgaac atttactaca gtttttaact   1800

ctactgtgta atataaaaga tcttgcagaa gt                                 1832


<210>  6475
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6475

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6476
<211>  1547
<212>  DNA
<213>  Homo sapiens

<400>  6476
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa    780

atgtctggag agccgagttg cagtgctgga agtccagaac aagaagctta tagaggaact    840

tgaaaccttg aaagacattt gttctcccaa aacagattac tagaaatatt taactatgaa    900

ctgaaggcag catgtatagt tgcttttgaa ggaatacaat atatagctgg caagaatggt    960

ggcttctttt ctttgtatca ttcatcttct tctttaatca cttaacattc ctaaaatgct   1020

tcactgtacg tagttaagtc gtagctataa cttcaaattt tttaaaagag acaaactgta   1080

aaaaatgtgt gtattcttaa aatgcaatat ttgtaaggct tgttccaatg ccacatactt   1140

gcagctccca ttctatgtgt catcaatagt gtcctatgca ataaaattat ttgcaggtct   1200

ttaaatcatt ttaggaaagg atgatcaaaa ataatgcatc cagcagtaca ataaaagtaa   1260

accacaaaaa aatacctcag gaaagaatag aaagaaagtc tatctaatga catgcctata   1320

tgagaagaat agcctagata tgaatatatg gcatttgcag atttttatat tagttgcttt   1380

gttaaaaaaa aaaagattgt attgctgtcc ttgaatgcca tagtcaaaga gagtttttaa   1440

tagaaccatg ttggttgcac tttgtagtgt ttggtgctca tttaaatatc tgaacattta   1500

ctacagtttt taactctact gtgtaatata aaagatcttg cagaagt                 1547


<210>  6477
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  6477

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn 
                85                  90                  95


Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro 
            100                 105                 110


Lys Thr Asp Tyr 
        115


<210>  6478
<211>  1708
<212>  DNA
<213>  Homo sapiens

<400>  6478
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    540

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    600

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg    660

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg    720

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa    780

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt    840

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa    900

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt    960

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1020

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1080

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1140

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1200

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1260

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1320

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc tttaaatcat tttaggaaag   1380

gatgatcaaa aataatgcat ccagcagtac aataaaagta aaccacaaaa aaatacctca   1440

ggaaagaata gaaagaaagt ctatctaatg acatgcctat atgagaagaa tagcctagat   1500

atgaatatat ggcatttgca gatttttata ttagttgctt tgttaaaaaa aaaaagattg   1560

tattgctgtc cttgaatgcc atagtcaaag agagttttta atagaaccat gttggttgca   1620

ctttgtagtg tttggtgctc atttaaatat ctgaacattt actacagttt ttaactctac   1680

tgtgtaatat aaaagatctt gcagaagt                                      1708


<210>  6479
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6479

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6480
<211>  1949
<212>  DNA
<213>  Homo sapiens

<400>  6480
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgcccggga gtgtcgcagg aagaagaaag aatatgtcaa    780

atgtcttgaa aatcgtgtgg ctgtgcttga aaaccaaaac aagactctca ttgaggaact    840

caaggccctc aaagatcttt attgccataa agtagagtaa ctgtctttga cttggacctt    900

gtttactcta atcaaggcag gagatgcagc agtcctactt attgccatgt ggacttgtgg    960

gaaggacacg tgtgaccctt aagaatccag tttggattag tgtttgaaat tgaattggga   1020

atgttgttcc aggatgtgga atgcagccgt gatcacactt accgagctta ctttgatctg   1080

tttgtcaata gcatgcaaaa aatgctttgt ttgccctttg cttctgcttt ttttcaggga   1140

agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta aaatgtctgg agagccgagt   1200

tgcagtgctg gaagtccaga acaagaagct tatagaggaa cttgaaacct tgaaagacat   1260

ttgttctccc aaaacagatt actagaaata tttaactatg aactgaaggc agcatgtata   1320

gttgcttttg aaggaataca atatatagct ggcaagaatg gtggcttctt ttctttgtat   1380

cattcatctt cttctttaat cacttaacat tcctaaaatg cttcactgta cgtagttaag   1440

tcgtagctat aacttcaaat tttttaaaag agacaaactg taaaaaatgt gtgtattctt   1500

aaaatgcaat atttgtaagg cttgttccaa tgccacatac ttgcagctcc cattctatgt   1560

gtcatcaata gtgtcctatg caataaaatt atttgcaggt ctttaaatca ttttaggaaa   1620

ggatgatcaa aaataatgca tccagcagta caataaaagt aaaccacaaa aaaatacctc   1680

aggaaagaat agaaagaaag tctatctaat gacatgccta tatgagaaga atagcctaga   1740

tatgaatata tggcatttgc agatttttat attagttgct ttgttaaaaa aaaaaagatt   1800

gtattgctgt ccttgaatgc catagtcaaa gagagttttt aatagaacca tgttggttgc   1860

actttgtagt gtttggtgct catttaaata tctgaacatt tactacagtt tttaactcta   1920

ctgtgtaata taaaagatct tgcagaagt                                     1949


<210>  6481
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6481

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn 
                85                  90                  95


Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His 
            100                 105                 110


Lys Val Glu 
        115


<210>  6482
<211>  1306
<212>  DNA
<213>  Homo sapiens

<400>  6482
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    540

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    600

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac    660

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg    720

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt    780

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa    840

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg    900

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt    960

taaatcattt taggaaagga tgatcaaaaa taatgcatcc agcagtacaa taaaagtaaa   1020

ccacaaaaaa atacctcagg aaagaataga aagaaagtct atctaatgac atgcctatat   1080

gagaagaata gcctagatat gaatatatgg catttgcaga tttttatatt agttgctttg   1140

ttaaaaaaaa aaagattgta ttgctgtcct tgaatgccat agtcaaagag agtttttaat   1200

agaaccatgt tggttgcact ttgtagtgtt tggtgctcat ttaaatatct gaacatttac   1260

tacagttttt aactctactg tgtaatataa aagatcttgc agaagt                  1306


<210>  6483
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  6483

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile 
65                  70                  75                  80


Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                85                  90                  95


<210>  6484
<211>  1613
<212>  DNA
<213>  Homo sapiens

<400>  6484
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg gaagctgcca aagaatgtcg acgtcgaaag aaagaatatg taaaatgtct    360

ggagagccga gttgcagtgc tggaagtcca gaacaagaag cttatagagg aacttgaaac    420

cttgaaagac atttgttctc ccaaaacaga ttactagaaa tatttaacta tgaactgaag    480

gcagcatgta tagttgcttt tgaaggaata caatatatag ctggcaagaa tggtggcttc    540

ttttctttgt atcattcatc ttcttcttta atcacttaac attcctaaaa tgcttcactg    600

tacgtagtta agtcgtagct ataacttcaa attttttaaa agagacaaac tgtaaaaaat    660

gtgtgtattc ttaaaatgca atatttgtaa ggcttgttcc aatgccacat acttgcagct    720

cccattctat gtgtcatcaa tagtgtccta tgcaataaaa ttatttgcag gtctttaaat    780

cattttagga aaggatgatc aaaaataatg catccagcag tacaataaaa gtaaaccaca    840

aaaaaatacc tcaggaaaga atagaaagaa agtctatcta atgacatgcc tatatgagaa    900

gaatagccta gatatgaata tatggcattt gcagattttt atattagttg ctttgttaaa    960

aaaaaaaaga ttgtattgct gtccttgaat gccatagtca aagagagttt ttaatagaac   1020

catgttggtt gcactttgta gtgtttggtg ctcatttaaa tatctgaaca tttactacag   1080

tttttaactc tactgtgtaa tataaaagat cttgcagaag ttcttagtgt tggtttaata   1140

ttacctaatg aaagtgatga catatttttt atatctggaa tgagcctgtt gggatcgcat   1200

tgcatacctt cggggtacaa gtcagtttct acactgggtg ctgatccttg cacgcgccct   1260

ttctaccatc tcacggtggg gatggccgca gggctgtgca cccagaagaa gatggctgtt   1320

agcgtttcgg ccttcataat ggcctgagac tttctttctg taggtggtct ggagctgtcc   1380

ggctggtggc cccctatttt gccatttagc gaacaaccac aggaatttta aaaacaaaaa   1440

catcccaaga ttttttcatt tcaaaatgct tcaaagtcca cattagatca gatactccgc   1500

tgtcggcaca ttcagctgag gttcattaca atcgagactg caatgtgatc tatgtttcat   1560

cttgttttta taataaaaag cttcagggaa caagcccaaa gccctcacca cag          1613


<210>  6485
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  6485

Met Ser Leu Leu Gly Ser His Cys Ile Pro Ser Gly Tyr Lys Ser Val 
1               5                   10                  15


Ser Thr Leu Gly Ala Asp Pro Cys Thr Arg Pro Phe Tyr His Leu Thr 
            20                  25                  30


Val Gly Met Ala Ala Gly Leu Cys Thr Gln Lys Lys Met Ala Val Ser 
        35                  40                  45


Val Ser Ala Phe Ile Met Ala 
    50                  55


<210>  6486
<211>  1798
<212>  DNA
<213>  Homo sapiens

<400>  6486
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    540

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    600

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac    660

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg    720

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt    780

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa    840

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg    900

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt    960

taaatcattt taggaaagga tgatcaaaaa taatgcatcc agcagtacaa taaaagtaaa   1020

ccacaaaaaa atacctcagg aaagaataga aagaaagtct atctaatgac atgcctatat   1080

gagaagaata gcctagatat gaatatatgg catttgcaga tttttatatt agttgctttg   1140

ttaaaaaaaa aaagattgta ttgctgtcct tgaatgccat agtcaaagag agtttttaat   1200

agaaccatgt tggttgcact ttgtagtgtt tggtgctcat ttaaatatct gaacatttac   1260

tacagttttt aactctactg tgtaatataa aagatcttgc agaagttctt agtgttggtt   1320

taatattacc taatgaaagt gatgacatat tttttatatc tggaatgagc ctgttgggat   1380

cgcattgcat accttcgggg tacaagtcag tttctacact gggtgctgat ccttgcacgc   1440

gccctttcta ccatctcacg gtggggatgg ccgcagggct gtgcacccag aagaagatgg   1500

ctgttagcgt ttcggccttc ataatggcct gagactttct ttctgtaggt ggtctggagc   1560

tgtccggctg gtggccccct attttgccat ttagcgaaca accacaggaa ttttaaaaac   1620

aaaaacatcc caagattttt tcatttcaaa atgcttcaaa gtccacatta gatcagatac   1680

tccgctgtcg gcacattcag ctgaggttca ttacaatcga gactgcaatg tgatctatgt   1740

ttcatcttgt ttttataata aaaagcttca gggaacaagc ccaaagccct caccacag     1798


<210>  6487
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  6487

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile 
65                  70                  75                  80


Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                85                  90                  95


<210>  6488
<211>  2324
<212>  DNA
<213>  Homo sapiens

<400>  6488
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggaca aatgaccatg gaaacagttg    360

aatcccagca tgatggaagt ataacagctt ctttgacaga gagcaagtct gctcatgtgc    420

agactcagac tggccaaaat tcaatccctg ctttagctca gctgccactg gtgacatgcc    480

aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga tggctgcatc    540

gcccggaagt ttgcacagtc cccagcagct ggcagaagaa gcaacacgca aacgagagct    600

gaggctaatg aaaaacaggg aagctgcccg ggagtgtcgc aggaagaaga aagaatatgt    660

caaatgtctt gaaaatcgtg tggctgtgct tgaaaaccaa aacaagactc tcattgagga    720

actcaaggcc ctcaaagatc tttattgcca taaagtagag taactgtctt tgacttggac    780

cttgtttact ctaatcaagg caggagatgc agcagtccta cttattgcca tgtggacttg    840

tgggaaggac acgtgtgacc cttaagaatc cagtttggat tagtgtttga aattgaattg    900

ggaatgttgt tccaggatgt ggaatgcagc cgtgatcaca cttaccgagc ttactttgat    960

ctgtttgtca atagcatgca aaaaatgctt tgtttgccct ttgcttctgc tttttttcag   1020

ggaagctgcc aaagaatgtc gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg   1080

agttgcagtg ctggaagtcc agaacaagaa gcttatagag gaacttgaaa ccttgaaaga   1140

catttgttct cccaaaacag attactagaa atatttaact atgaactgaa ggcagcatgt   1200

atagttgctt ttgaaggaat acaatatata gctggcaaga atggtggctt cttttctttg   1260

tatcattcat cttcttcttt aatcacttaa cattcctaaa atgcttcact gtacgtagtt   1320

aagtcgtagc tataacttca aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt   1380

cttaaaatgc aatatttgta aggcttgttc caatgccaca tacttgcagc tcccattcta   1440

tgtgtcatca atagtgtcct atgcaataaa attatttgca ggtctttaaa tcattttagg   1500

aaaggatgat caaaaataat gcatccagca gtacaataaa agtaaaccac aaaaaaatac   1560

ctcaggaaag aatagaaaga aagtctatct aatgacatgc ctatatgaga agaatagcct   1620

agatatgaat atatggcatt tgcagatttt tatattagtt gctttgttaa aaaaaaaaag   1680

attgtattgc tgtccttgaa tgccatagtc aaagagagtt tttaatagaa ccatgttggt   1740

tgcactttgt agtgtttggt gctcatttaa atatctgaac atttactaca gtttttaact   1800

ctactgtgta atataaaaga tcttgcagaa gttcttagtg ttggtttaat attacctaat   1860

gaaagtgatg acatattttt tatatctgga atgagcctgt tgggatcgca ttgcatacct   1920

tcggggtaca agtcagtttc tacactgggt gctgatcctt gcacgcgccc tttctaccat   1980

ctcacggtgg ggatggccgc agggctgtgc acccagaaga agatggctgt tagcgtttcg   2040

gccttcataa tggcctgaga ctttctttct gtaggtggtc tggagctgtc cggctggtgg   2100

ccccctattt tgccatttag cgaacaacca caggaatttt aaaaacaaaa acatcccaag   2160

attttttcat ttcaaaatgc ttcaaagtcc acattagatc agatactccg ctgtcggcac   2220

attcagctga ggttcattac aatcgagact gcaatgtgat ctatgtttca tcttgttttt   2280

ataataaaaa gcttcaggga acaagcccaa agccctcacc acag                    2324


<210>  6489
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6489

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6490
<211>  2200
<212>  DNA
<213>  Homo sapiens

<400>  6490
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcggctg ccactggtga catgccaact    360

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    420

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    480

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    540

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    600

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg    660

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg    720

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa    780

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt    840

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa    900

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt    960

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1020

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1080

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1140

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1200

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1260

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1320

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc tttaaatcat tttaggaaag   1380

gatgatcaaa aataatgcat ccagcagtac aataaaagta aaccacaaaa aaatacctca   1440

ggaaagaata gaaagaaagt ctatctaatg acatgcctat atgagaagaa tagcctagat   1500

atgaatatat ggcatttgca gatttttata ttagttgctt tgttaaaaaa aaaaagattg   1560

tattgctgtc cttgaatgcc atagtcaaag agagttttta atagaaccat gttggttgca   1620

ctttgtagtg tttggtgctc atttaaatat ctgaacattt actacagttt ttaactctac   1680

tgtgtaatat aaaagatctt gcagaagttc ttagtgttgg tttaatatta cctaatgaaa   1740

gtgatgacat attttttata tctggaatga gcctgttggg atcgcattgc ataccttcgg   1800

ggtacaagtc agtttctaca ctgggtgctg atccttgcac gcgccctttc taccatctca   1860

cggtggggat ggccgcaggg ctgtgcaccc agaagaagat ggctgttagc gtttcggcct   1920

tcataatggc ctgagacttt ctttctgtag gtggtctgga gctgtccggc tggtggcccc   1980

ctattttgcc atttagcgaa caaccacagg aattttaaaa acaaaaacat cccaagattt   2040

tttcatttca aaatgcttca aagtccacat tagatcagat actccgctgt cggcacattc   2100

agctgaggtt cattacaatc gagactgcaa tgtgatctat gtttcatctt gtttttataa   2160

taaaaagctt cagggaacaa gcccaaagcc ctcaccacag                         2200


<210>  6491
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  6491

Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly 
1               5                   10                  15


Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg 
        35                  40                  45


Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys 
    50                  55                  60


Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile 
65                  70                  75                  80


Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                85                  90                  95


<210>  6492
<211>  2699
<212>  DNA
<213>  Homo sapiens

<400>  6492
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggat aaataaagaa aacaggaaag    360

gaggaaagca ttgattacaa atatcttaac aatgagcaaa tgtgcaagga aaaaatatat    420

taagacaaat ccaagacaaa tgaccatgga aacagttgaa tcccagcatg atggaagtat    480

aacagcttct ttgacagaga gcaagtctgc tcatgtgcag actcagactg gccaaaattc    540

aatccctgct ttagctcagg tagcagcaat tgcagagaca gatgaatctg cagaatcaga    600

aggtgtaatt gattctcata aacgtagaga aatcctttca cgaagaccct cttataggaa    660

aatactgaat gaactgtcct ctgatgtgcc tggtgttccc aagattgaag aagagagatc    720

agaggaagaa ggaacaccac ctagtattgc taccatggca gtaccaacta gcatatatca    780

gactagcacg gggcaataca atgaggaaac tgaacttgcc ccaagtcaca tggctgctgc    840

cactggtgac atgccaactt accagatccg agctcctact gctgctttgc cacagggagt    900

ggtgatggct gcatcgcccg gaagtttgca cagtccccag cagctggcag aagaagcaac    960

acgcaaacga gagctgaggc taatgaaaaa cagggaagct gcccgggagt gtcgcaggaa   1020

gaagaaagaa tatgtcaaat gtcttgaaaa tcgtgtggct gtgcttgaaa accaaaacaa   1080

gactctcatt gaggaactca aggccctcaa agatctttat tgccataaag tagagtaact   1140

gtctttgact tggaccttgt ttactctaat caaggcagga gatgcagcag tcctacttat   1200

tgccatgtgg acttgtggga aggacacgtg tgacccttaa gaatccagtt tggattagtg   1260

tttgaaattg aattgggaat gttgttccag gatgtggaat gcagccgtga tcacacttac   1320

cgagcttact ttgatctgtt tgtcaatagc atgcaaaaaa tgctttgttt gccctttgct   1380

tctgcttttt ttcagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa   1440

atgtctggag agccgagttg cagtgctgga agtccagaac aagaagctta tagaggaact   1500

tgaaaccttg aaagacattt gttctcccaa aacagattac tagaaatatt taactatgaa   1560

ctgaaggcag catgtatagt tgcttttgaa ggaatacaat atatagctgg caagaatggt   1620

ggcttctttt ctttgtatca ttcatcttct tctttaatca cttaacattc ctaaaatgct   1680

tcactgtacg tagttaagtc gtagctataa cttcaaattt tttaaaagag acaaactgta   1740

aaaaatgtgt gtattcttaa aatgcaatat ttgtaaggct tgttccaatg ccacatactt   1800

gcagctccca ttctatgtgt catcaatagt gtcctatgca ataaaattat ttgcaggtct   1860

ttaaatcatt ttaggaaagg atgatcaaaa ataatgcatc cagcagtaca ataaaagtaa   1920

accacaaaaa aatacctcag gaaagaatag aaagaaagtc tatctaatga catgcctata   1980

tgagaagaat agcctagata tgaatatatg gcatttgcag atttttatat tagttgcttt   2040

gttaaaaaaa aaaagattgt attgctgtcc ttgaatgcca tagtcaaaga gagtttttaa   2100

tagaaccatg ttggttgcac tttgtagtgt ttggtgctca tttaaatatc tgaacattta   2160

ctacagtttt taactctact gtgtaatata aaagatcttg cagaagttct tagtgttggt   2220

ttaatattac ctaatgaaag tgatgacata ttttttatat ctggaatgag cctgttggga   2280

tcgcattgca taccttcggg gtacaagtca gtttctacac tgggtgctga tccttgcacg   2340

cgccctttct accatctcac ggtggggatg gccgcagggc tgtgcaccca gaagaagatg   2400

gctgttagcg tttcggcctt cataatggcc tgagactttc tttctgtagg tggtctggag   2460

ctgtccggct ggtggccccc tattttgcca tttagcgaac aaccacagga attttaaaaa   2520

caaaaacatc ccaagatttt ttcatttcaa aatgcttcaa agtccacatt agatcagata   2580

ctccgctgtc ggcacattca gctgaggttc attacaatcg agactgcaat gtgatctatg   2640

tttcatcttg tttttataat aaaaagcttc agggaacaag cccaaagccc tcaccacag    2699


<210>  6493
<211>  248
<212>  PRT
<213>  Homo sapiens

<400>  6493

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Asn Glu Glu Thr Glu Leu Ala Pro 
    130                 135                 140


Ser His Met Ala Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg 
145                 150                 155                 160


Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro 
                165                 170                 175


Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys 
            180                 185                 190


Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg 
        195                 200                 205


Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val 
    210                 215                 220


Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys 
225                 230                 235                 240


Asp Leu Tyr Cys His Lys Val Glu 
                245


<210>  6494
<211>  2039
<212>  DNA
<213>  Homo sapiens

<400>  6494
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgccaaaga atgtcgacgt cgaaagaaag aatatgtaaa    780

atgtctggag agccgagttg cagtgctgga agtccagaac aagaagctta tagaggaact    840

tgaaaccttg aaagacattt gttctcccaa aacagattac tagaaatatt taactatgaa    900

ctgaaggcag catgtatagt tgcttttgaa ggaatacaat atatagctgg caagaatggt    960

ggcttctttt ctttgtatca ttcatcttct tctttaatca cttaacattc ctaaaatgct   1020

tcactgtacg tagttaagtc gtagctataa cttcaaattt tttaaaagag acaaactgta   1080

aaaaatgtgt gtattcttaa aatgcaatat ttgtaaggct tgttccaatg ccacatactt   1140

gcagctccca ttctatgtgt catcaatagt gtcctatgca ataaaattat ttgcaggtct   1200

ttaaatcatt ttaggaaagg atgatcaaaa ataatgcatc cagcagtaca ataaaagtaa   1260

accacaaaaa aatacctcag gaaagaatag aaagaaagtc tatctaatga catgcctata   1320

tgagaagaat agcctagata tgaatatatg gcatttgcag atttttatat tagttgcttt   1380

gttaaaaaaa aaaagattgt attgctgtcc ttgaatgcca tagtcaaaga gagtttttaa   1440

tagaaccatg ttggttgcac tttgtagtgt ttggtgctca tttaaatatc tgaacattta   1500

ctacagtttt taactctact gtgtaatata aaagatcttg cagaagttct tagtgttggt   1560

ttaatattac ctaatgaaag tgatgacata ttttttatat ctggaatgag cctgttggga   1620

tcgcattgca taccttcggg gtacaagtca gtttctacac tgggtgctga tccttgcacg   1680

cgccctttct accatctcac ggtggggatg gccgcagggc tgtgcaccca gaagaagatg   1740

gctgttagcg tttcggcctt cataatggcc tgagactttc tttctgtagg tggtctggag   1800

ctgtccggct ggtggccccc tattttgcca tttagcgaac aaccacagga attttaaaaa   1860

caaaaacatc ccaagatttt ttcatttcaa aatgcttcaa agtccacatt agatcagata   1920

ctccgctgtc ggcacattca gctgaggttc attacaatcg agactgcaat gtgatctatg   1980

tttcatcttg tttttataat aaaaagcttc agggaacaag cccaaagccc tcaccacag    2039


<210>  6495
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  6495

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn 
                85                  90                  95


Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro 
            100                 105                 110


Lys Thr Asp Tyr 
        115


<210>  6496
<211>  2441
<212>  DNA
<213>  Homo sapiens

<400>  6496
gtggcgcttc actcctgctg gcggccggca gggggcggag ttcgagcctg gatttttttc     60

ctcggggcct cccccgggag gccgtcccgg cgtgggggag gggaggacgg ggcgggagga    120

cgcggttcgg tcggctgcag cgctactttt ggtccggggt cggcagggag gccgcggcta    180

ccgcatcaca gctgacgtga ggactacgtg gggccgctgc cggctccggg ttgctgggcg    240

gcggcgccgc tgctgagcgg cggtcgggct cgccgtctcc acctcctcgc gtccgtaatc    300

agtgacgagg tccgctacgt aaatcccttt gcggcgggta gcagcaattg cagagacaga    360

tgaatctgca gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg    420

aagaccctct tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa    480

gattgaagaa gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt    540

accaactagc atatatcaga ctagcacggg gcaatacact gccactggtg acatgccaac    600

ttaccagatc cgagctccta ctgctgcttt gccacaggga gtggtgatgg ctgcatcgcc    660

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    720

gctaatgaaa aacagggaag ctgcccggga gtgtcgcagg aagaagaaag aatatgtcaa    780

atgtcttgaa aatcgtgtgg ctgtgcttga aaaccaaaac aagactctca ttgaggaact    840

caaggccctc aaagatcttt attgccataa agtagagtaa ctgtctttga cttggacctt    900

gtttactcta atcaaggcag gagatgcagc agtcctactt attgccatgt ggacttgtgg    960

gaaggacacg tgtgaccctt aagaatccag tttggattag tgtttgaaat tgaattggga   1020

atgttgttcc aggatgtgga atgcagccgt gatcacactt accgagctta ctttgatctg   1080

tttgtcaata gcatgcaaaa aatgctttgt ttgccctttg cttctgcttt ttttcaggga   1140

agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta aaatgtctgg agagccgagt   1200

tgcagtgctg gaagtccaga acaagaagct tatagaggaa cttgaaacct tgaaagacat   1260

ttgttctccc aaaacagatt actagaaata tttaactatg aactgaaggc agcatgtata   1320

gttgcttttg aaggaataca atatatagct ggcaagaatg gtggcttctt ttctttgtat   1380

cattcatctt cttctttaat cacttaacat tcctaaaatg cttcactgta cgtagttaag   1440

tcgtagctat aacttcaaat tttttaaaag agacaaactg taaaaaatgt gtgtattctt   1500

aaaatgcaat atttgtaagg cttgttccaa tgccacatac ttgcagctcc cattctatgt   1560

gtcatcaata gtgtcctatg caataaaatt atttgcaggt ctttaaatca ttttaggaaa   1620

ggatgatcaa aaataatgca tccagcagta caataaaagt aaaccacaaa aaaatacctc   1680

aggaaagaat agaaagaaag tctatctaat gacatgccta tatgagaaga atagcctaga   1740

tatgaatata tggcatttgc agatttttat attagttgct ttgttaaaaa aaaaaagatt   1800

gtattgctgt ccttgaatgc catagtcaaa gagagttttt aatagaacca tgttggttgc   1860

actttgtagt gtttggtgct catttaaata tctgaacatt tactacagtt tttaactcta   1920

ctgtgtaata taaaagatct tgcagaagtt cttagtgttg gtttaatatt acctaatgaa   1980

agtgatgaca tattttttat atctggaatg agcctgttgg gatcgcattg cataccttcg   2040

gggtacaagt cagtttctac actgggtgct gatccttgca cgcgcccttt ctaccatctc   2100

acggtgggga tggccgcagg gctgtgcacc cagaagaaga tggctgttag cgtttcggcc   2160

ttcataatgg cctgagactt tctttctgta ggtggtctgg agctgtccgg ctggtggccc   2220

cctattttgc catttagcga acaaccacag gaattttaaa aacaaaaaca tcccaagatt   2280

ttttcatttc aaaatgcttc aaagtccaca ttagatcaga tactccgctg tcggcacatt   2340

cagctgaggt tcattacaat cgagactgca atgtgatcta tgtttcatct tgtttttata   2400

ataaaaagct tcagggaaca agcccaaagc cctcaccaca g                       2441


<210>  6497
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6497

Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr 
1               5                   10                  15


Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala 
            20                  25                  30


Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His Ser 
        35                  40                  45


Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu 
    50                  55                  60


Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg Arg Lys Lys Lys Glu 
65                  70                  75                  80


Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val Leu Glu Asn Gln Asn 
                85                  90                  95


Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys Asp Leu Tyr Cys His 
            100                 105                 110


Lys Val Glu 
        115


<210>  6498
<211>  504
<212>  DNA
<213>  Homo sapiens

<400>  6498
atggccctaa aaaggcaaga ctcaggcaga agggaaaatg cgccttccga gagcggtcgc     60

ggctctgccc ttcccactcc ggagactgcc cgcgcccggg accgaatgac tcagctgcga    120

ggccctccgg cccaggtttt gggggaaaac gggctgcgtc cgctttcgtc taaactgcgc    180

tctccttggc ccggccccgg ggtcccggcc cgccgcccac ggctccgctc ggcctctgct    240

gctccaccgc acccggctcc gctccgcctc ctgcctccac ctccacctcc tgcgccgcgt    300

cgcccgctgc tgggtctcgg ggccggagcc gacgcaccac ttacccgccg caaagggatt    360

tacgtagcgg acctcgtcac tgattacgga cgcgaggagg tggagacggc gagcccgacc    420

gccgctcagc agcggcgccg ccgcccagca acccggagcc ggcagcggcc ccacgtagtc    480

ctcacgtcag ctgtgatgcg gtag                                           504


<210>  6499
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  6499

Met Ala Leu Lys Arg Gln Asp Ser Gly Arg Arg Glu Asn Ala Pro Ser 
1               5                   10                  15


Glu Ser Gly Arg Gly Ser Ala Leu Pro Thr Pro Glu Thr Ala Arg Ala 
            20                  25                  30


Arg Asp Arg Met Thr Gln Leu Arg Gly Pro Pro Ala Gln Val Leu Gly 
        35                  40                  45


Glu Asn Gly Leu Arg Pro Leu Ser Ser Lys Leu Arg Ser Pro Trp Pro 
    50                  55                  60


Gly Pro Gly Val Pro Ala Arg Arg Pro Arg Leu Arg Ser Ala Ser Ala 
65                  70                  75                  80


Ala Pro Pro His Pro Ala Pro Leu Arg Leu Leu Pro Pro Pro Pro Pro 
                85                  90                  95


Pro Ala Pro Arg Arg Pro Leu Leu Gly Leu Gly Ala Gly Ala Asp Ala 
            100                 105                 110


Pro Leu Thr Arg Arg Lys Gly Ile Tyr Val Ala Asp Leu Val Thr Asp 
        115                 120                 125


Tyr Gly Arg Glu Glu Val Glu Thr Ala Ser Pro Thr Ala Ala Gln Gln 
    130                 135                 140


Arg Arg Arg Arg Pro Ala Thr Arg Ser Arg Gln Arg Pro His Val Val 
145                 150                 155                 160


Leu Thr Ser Ala Val Met Arg 
                165


<210>  6500
<211>  948
<212>  DNA
<213>  Homo sapiens

<400>  6500
cagtgacgag gtccgctacg taaatccctt tgcggcggga taaataaaga aaacaggaaa     60

ggaggaaagc attgattaca aatatcttaa caatgagcaa atgtgcaagg aaaaaatata    120

ttaagacaaa tccaaggtag cagcaattgc agagacagat gaatctgcag aatcagaagg    180

tgtaattgat tctcataaac gtagagaaat cctttcacga agaccctctt ataggaaaat    240

actgaatgaa ctgtcctctg atgtgcctgg tgttcccaag attgaagaag agagatcaga    300

ggaagaagga acaccaccta gtattgctac catggcagta ccaactagca tatatcagac    360

tagcacgggg caatacagta tgtatgctgc aattcgatat gatacagtgc tagctttaag    420

tcttctctag ttatattgaa gcaactcagg ttttggcatt aaattgttcc attttaaaat    480

gcatcattaa tacctaaact gtatcataga atgaaagtat atgttaaaaa gtgagatctt    540

tgtattgaca gctgtcatat aattttgaaa agtaaaaatt ttgactgccg aatatagaag    600

aaaattttgg ggtaaaaagg agaatttttc ctatttacat gtttatatta atctctagta    660

aaacattgtt tttgttgtct ttatgatgca tgcgaacata aatgtctgta tttcattctt    720

gttggctttt gttacccaca attacatact attcttacta atctgagagt tttctaaagt    780

atgttttcaa tgtttcacta ctctctactc tgttaatttg tgctacagtt tttcctaaaa    840

gagaatggaa aaatgattta attttttaaa ctgtagcaat tggatagata attttatttg    900

aaattttaca cactgaaagc tctaaataaa cagatacatt cacattca                 948


<210>  6501
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  6501

Met Asn Cys Pro Leu Met Cys Leu Val Phe Pro Arg Leu Lys Lys Arg 
1               5                   10                  15


Asp Gln Arg Lys Lys Glu His His Leu Val Leu Leu Pro Trp Gln Tyr 
            20                  25                  30


Gln Leu Ala Tyr Ile Arg Leu Ala Arg Gly Asn Thr Val Cys Met Leu 
        35                  40                  45


Gln Phe Asp Met Ile Gln Cys 
    50                  55


<210>  6502
<211>  1081
<212>  DNA
<213>  Homo sapiens

<400>  6502
ccgccccacg cccgcttcgt gcgctcagct gccccgggac ccgcctgcct cctcgcgaac     60

ttgggacgag ttggaaaatc ctccctgaga gagccgtgcg gctcagggga gcggtttaac    120

tcggaaaagg aaaaggaatc cagaaacaaa tgaccatgga aacagttgaa tcccagcatg    180

atggaagtat aacagcttct ttgacagaga gcaagtctgc tcatgtgcag actcagactg    240

gccaaaattc aatccctgct ttagctcagg tagcagcaat tgcagagaca gatgaatctg    300

cagaatcaga aggtgtaatt gattctcata aacgtagaga aatcctttca cgaagaccct    360

cttataggaa aatactgaat gaactgtcct ctgatgtgcc tggtgttccc aagattgaag    420

aagagagatc agaggaagaa ggaacaccac ctagtattgc taccatggca gtaccaacta    480

gcatatatca gactagcacg gggcaataca gtatgtatgc tgcaattcga tatgatacag    540

tgctagcttt aagtcttctc tagttatatt gaagcaactc aggttttggc attaaattgt    600

tccattttaa aatgcatcat taatacctaa actgtatcat agaatgaaag tatatgttaa    660

aaagtgagat ctttgtattg acagctgtca tataattttg aaaagtaaaa attttgactg    720

ccgaatatag aagaaaattt tggggtaaaa aggagaattt ttcctattta catgtttata    780

ttaatctcta gtaaaacatt gtttttgttg tctttatgat gcatgcgaac ataaatgtct    840

gtatttcatt cttgttggct tttgttaccc acaattacat actattctta ctaatctgag    900

agttttctaa agtatgtttt caatgtttca ctactctcta ctctgttaat ttgtgctaca    960

gtttttccta aaagagaatg gaaaaatgat ttaatttttt aaactgtagc aattggatag   1020

ataattttat ttgaaatttt acacactgaa agctctaaat aaacagatac attcacattc   1080

a                                                                   1081


<210>  6503
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  6503

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
        35                  40                  45


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
    50                  55                  60


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
65                  70                  75                  80


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
                85                  90                  95


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
            100                 105                 110


Tyr Gln Thr Ser Thr Gly Gln Tyr Ser Met Tyr Ala Ala Ile Arg Tyr 
        115                 120                 125


Asp Thr Val Leu Ala Leu Ser Leu Leu 
    130                 135


<210>  6504
<211>  627
<212>  DNA
<213>  Homo sapiens

<400>  6504
cgggacccgc ctgcctcctc gcgaacttgg gacgagttgg aaaatcctcc ctgagagagc     60

cgtgcggctc aggggagcgg tttaactcgg aaaaggaaaa ggaatccaga agataaataa    120

agaaaacagg aaaggaggaa agcattgatt acaaatatct taacaatgag caaatgtgca    180

aggaaaaaat atattaagac aaatccaaga caaatgacca tggaaacagt tgaatcccag    240

catgatggaa gtataacagc ttctttgaca gagagcaagt ctgctcatgt gcagactcag    300

actggccaaa attcaatccc tgctttagct caggtagcag caattgcaga gacagatgaa    360

tctgcagaat cagaaggtgt aattgattct cataaacgta gagaaatcct ttcacgaaga    420

ccctcttata ggaaaatact gaatgaactg tcctctgatg tgcctggtgt tcccaagatt    480

gaagaagaga gatcagagga agaaggaaca ccacctagta ttgctaccat ggcagtacca    540

actagcatat atcagactag cacggggcaa tacattgcta tagcccaagg tggaacaatc    600

cagatttcta acccaggatc tgatggt                                        627


<210>  6505
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  6505

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr 
    130                 135                 140


Ile Gln Ile Ser Asn Pro Gly Ser Asp 
145                 150


<210>  6506
<211>  2221
<212>  DNA
<213>  Homo sapiens

<400>  6506
gacccgcctg cctcctcgcg aacttgggac gagttggaaa atcctccctg agagagccgt     60

gcggctcagg ggagcggttt aactcggaaa aggaaaagga atccagaaga taaataaaga    120

aaacaggaaa ggaggaaagc attgattaca aatatcttaa caatgagcaa atgtgcaagg    180

aaaaaatata ttaagacaaa tccaagacaa atgaccatgg aaacagttga atcccagcat    240

gatggaagta taacagcttc tttgacagag agcaagtctg ctcatgtgca gactcagact    300

ggccaaaatt caatccctgc tttagctcag gtagcagcaa ttgcagagac agatgaatct    360

gcagaatcag aaggtgtaat tgattctcat aaacgtagag aaatcctttc acgaagaccc    420

tcttatagga aaatactgaa tgaactgtcc tctgatgtgc ctggtgttcc caagattgaa    480

gaagagagat cagaggaaga aggaacacca cctagtattg ctaccatggc agtaccaact    540

agcatatatc agactagcac ggggcaatac attgctatag cccaaggtgg aacaatccag    600

atttctaacc caggatctga tggtgttcag ggactgcagg cattaacaat gacaaattca    660

ggagctcctc caccaggtgc tacaattgta cagtacgcag cacaatcagc tgatggcaca    720

cagcagttct ttgtcccagg cagccaggtt gttgttcaag ctgccactgg tgacatgcca    780

acttaccaga tccgagctcc tactgctgct ttgccacagg gagtggtgat ggctgcatcg    840

cccggaagtt tgcacagtcc ccagcagctg gcagaagaag caacacgcaa acgagagctg    900

aggctaatga aaaacaggga agctgccaaa gaatgtcgac gtcgaaagaa agaatatgta    960

aaatgtctgg agagccgagt tgcagtgctg gaagtccaga acaagaagct tatagaggaa   1020

cttgaaacct tgaaagacat ttgttctccc aaaacagatt actagaaata tttaactatg   1080

aactgaaggc agcatgtata gttgcttttg aaggaataca atatatagct ggcaagaatg   1140

gtggcttctt ttctttgtat cattcatctt cttctttaat cacttaacat tcctaaaatg   1200

cttcactgta cgtagttaag tcgtagctat aacttcaaat tttttaaaag agacaaactg   1260

taaaaaatgt gtgtattctt aaaatgcaat atttgtaagg cttgttccaa tgccacatac   1320

ttgcagctcc cattctatgt gtcatcaata gtgtcctatg caataaaatt atttgcaggt   1380

ctttaaatca ttttaggaaa ggatgatcaa aaataatgca tccagcagta caataaaagt   1440

aaaccacaaa aaaatacctc aggaaagaat agaaagaaag tctatctaat gacatgccta   1500

tatgagaaga atagcctaga tatgaatata tggcatttgc agatttttat attagttgct   1560

ttgttaaaaa aaaaaagatt gtattgctgt ccttgaatgc catagtcaaa gagagttttt   1620

aatagaacca tgttggttgc actttgtagt gtttggtgct catttaaata tctgaacatt   1680

tactacagtt tttaactcta ctgtgtaata taaaagatct tgcagaagtt cttagtgttg   1740

gtttaatatt acctaatgaa agtgatgaca tattttttat atctggaatg agcctgttgg   1800

gatcgcattg cataccttcg gggtacaagt cagtttctac actgggtgct gatccttgca   1860

cgcgcccttt ctaccatctc acggtgggga tggccgcagg gctgtgcacc cagaagaaga   1920

tggctgttag cgtttcggcc ttcataatgg cctgagactt tctttctgta ggtggtctgg   1980

agctgtccgg ctggtggccc cctattttgc catttagcga acaaccacag gaattttaaa   2040

aacaaaaaca tcccaagatt ttttcatttc aaaatgcttc aaagtccaca ttagatcaga   2100

tactccgctg tcggcacatt cagctgaggt tcattacaat cgagactgca atgtgatcta   2160

tgtttcatct tgtttttata ataaaaagct tcagggaaca agcccaaagc cctcaccaca   2220

g                                                                   2221


<210>  6507
<211>  300
<212>  PRT
<213>  Homo sapiens

<400>  6507

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr 
    130                 135                 140


Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln Ala 
145                 150                 155                 160


Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val 
                165                 170                 175


Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro 
            180                 185                 190


Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr Tyr 
        195                 200                 205


Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala 
    210                 215                 220


Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala 
225                 230                 235                 240


Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Lys 
                245                 250                 255


Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser Arg 
            260                 265                 270


Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu Glu 
        275                 280                 285


Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
    290                 295                 300


<210>  6508
<211>  1934
<212>  DNA
<213>  Homo sapiens

<400>  6508
gacccgcctg cctcctcgcg aacttgggac gagttggaaa atcctccctg agagagccgt     60

gcggctcagg ggagcggttt aactcggaaa aggaaaagga atccagaaac aaatgaccat    120

ggaaacagtt gaatcccagc atgatggaag tataacagct tctttgacag agagcaagtc    180

tgctcatgtg cagactcaga ctggccaaaa ttcaatccct gctttagctc aggtagcagc    240

aattgcagag acagatgaat ctgcagaatc agaaggtgta attgattctc ataaacgtag    300

agaaatcctt tcacgaagac cctcttatag gaaaatactg aatgaactgt cctctgatgt    360

gcctggtgtt cccaagattg aagaagagag atcagaggaa gaaggaacac cacctagtat    420

tgctaccatg gcagtaccaa ctagcatata tcagactagc acggggcaat acactgccac    480

tggtgacatg ccaacttacc agatccgagc tcctactgct gctttgccac agggagtggt    540

gatggctgca tcgcccggaa gtttgcacag tccccagcag ctggcagaag aagcaacacg    600

caaacgagag ctgaggctaa tgaaaaacag ggaagctgcc aaagaatgtc gacgtcgaaa    660

gaaagaatat gtaaaatgtc tggagagccg agttgcagtg ctggaagtcc agaacaagaa    720

gcttatagag gaacttgaaa ccttgaaaga catttgttct cccaaaacag attactagaa    780

atatttaact atgaactgaa ggcagcatgt atagttgctt ttgaaggaat acaatatata    840

gctggcaaga atggtggctt cttttctttg tatcattcat cttcttcttt aatcacttaa    900

cattcctaaa atgcttcact gtacgtagtt aagtcgtagc tataacttca aattttttaa    960

aagagacaaa ctgtaaaaaa tgtgtgtatt cttaaaatgc aatatttgta aggcttgttc   1020

caatgccaca tacttgcagc tcccattcta tgtgtcatca atagtgtcct atgcaataaa   1080

attatttgca ggtctttaaa tcattttagg aaaggatgat caaaaataat gcatccagca   1140

gtacaataaa agtaaaccac aaaaaaatac ctcaggaaag aatagaaaga aagtctatct   1200

aatgacatgc ctatatgaga agaatagcct agatatgaat atatggcatt tgcagatttt   1260

tatattagtt gctttgttaa aaaaaaaaag attgtattgc tgtccttgaa tgccatagtc   1320

aaagagagtt tttaatagaa ccatgttggt tgcactttgt agtgtttggt gctcatttaa   1380

atatctgaac atttactaca gtttttaact ctactgtgta atataaaaga tcttgcagaa   1440

gttcttagtg ttggtttaat attacctaat gaaagtgatg acatattttt tatatctgga   1500

atgagcctgt tgggatcgca ttgcatacct tcggggtaca agtcagtttc tacactgggt   1560

gctgatcctt gcacgcgccc tttctaccat ctcacggtgg ggatggccgc agggctgtgc   1620

acccagaaga agatggctgt tagcgtttcg gccttcataa tggcctgaga ctttctttct   1680

gtaggtggtc tggagctgtc cggctggtgg ccccctattt tgccatttag cgaacaacca   1740

caggaatttt aaaaacaaaa acatcccaag attttttcat ttcaaaatgc ttcaaagtcc   1800

acattagatc agatactccg ctgtcggcac attcagctga ggttcattac aatcgagact   1860

gcaatgtgat ctatgtttca tcttgttttt ataataaaaa gcttcaggga acaagcccaa   1920

agccctcacc acag                                                     1934


<210>  6509
<211>  221
<212>  PRT
<213>  Homo sapiens

<400>  6509

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
        35                  40                  45


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
    50                  55                  60


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
65                  70                  75                  80


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
                85                  90                  95


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
            100                 105                 110


Tyr Gln Thr Ser Thr Gly Gln Tyr Thr Ala Thr Gly Asp Met Pro Thr 
        115                 120                 125


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
    130                 135                 140


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
145                 150                 155                 160


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
                165                 170                 175


Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser 
            180                 185                 190


Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu 
        195                 200                 205


Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
    210                 215                 220


<210>  6510
<211>  1870
<212>  DNA
<213>  Homo sapiens

<400>  6510
gataaataaa gaaaacagga aaggaggaaa gcattgatta caaatatctt aacaatgagc     60

aaatgtgcaa ggaaaaaata tattaagaca aatccaagac aaatgaccat ggaaacagtt    120

gaatcccagc atgatggaag tataacagct tctttgacag agagcaagtc tgctcatgtg    180

cagactcaga ctggccaaaa ttcaatccct gctttagctc aggtagcagc aattgcagag    240

acagatgaat ctgcagaatc agaaggtgta attgattctc ataaacgtag agaaatcctt    300

tcacgaagac cctcttatag gaaaatactg aatgaactgt cctctgatgt gcctggtgtt    360

cccaagattg aagaagagag atcagaggaa gaaggaacac cacctagtat tgctaccatg    420

gcagtaccaa ctagcatata tcagactagc acggggcaat acaatgagga aactgaactt    480

gccccaagtc acatggctgc tgccactggt gacatgccaa cttaccagat ccgagctcct    540

actgctgctt tgccacaggg agtggtgatg gctgcatcgc ccggaagttt gcacagtccc    600

cagcagctgg cagaagaagc aacacgcaaa cgagagctga ggctaatgaa aaacagggaa    660

gctgcccggg agtgtcgcag gaagaagaaa gaatatgtca aatgtcttga aaatcgtgtg    720

gctgtgcttg aaaaccaaaa caagactctc attgaggaac tcaaggccct caaagatctt    780

tattgccata aagtagagta actgtctttg acttggacct tgtttactct aatcaaggca    840

ggagatgcag cagtcctact tattgccatg tggacttgtg ggaaggacac gtgtgaccct    900

taagaatcca gtttggatta gtgtttgaaa ttgaattggg aatgttgttc caggatgtgg    960

aatgcagccg tgatcacact taccgagctt actttgatct gtttgtcaat agcatgcaaa   1020

aaatgctttg tttgcccttt gcttctgctt tttttcaggg aagctgccaa agaatgtcga   1080

cgtcgaaaga aagaatatgt aaaatgtctg gagagccgag ttgcagtgct ggaagtccag   1140

aacaagaagc ttatagagga acttgaaacc ttgaaagaca tttgttctcc caaaacagat   1200

tactagaaat atttaactat gaactgaagg cagcatgtat agttgctttt gaaggaatac   1260

aatatatagc tggcaagaat ggtggcttct tttctttgta tcattcatct tcttctttaa   1320

tcacttaaca ttcctaaaat gcttcactgt acgtagttaa gtcgtagcta taacttcaaa   1380

ttttttaaaa gagacaaact gtaaaaaatg tgtgtattct taaaatgcaa tatttgtaag   1440

gcttgttcca atgccacata cttgcagctc ccattctatg tgtcatcaat agtgtcctat   1500

gcaataaaat tatttgcagg tctttaaatc attttaggaa aggatgatca aaaataatgc   1560

atccagcagt acaataaaag taaaccacaa aaaaatacct caggaaagaa tagaaagaaa   1620

gtctatctaa tgacatgcct atatgagaag aatagcctag atatgaatat atggcatttg   1680

cagattttta tattagttgc tttgttaaaa aaaaaaagat tgtattgctg tccttgaatg   1740

ccatagtcaa agagagtttt taatagaacc atgttggttg cactttgtag tgtttggtgc   1800

tcatttaaat atctgaacat ttactacagt ttttaactct actgtgtaat ataaaagatc   1860

ttgcagaagt                                                          1870


<210>  6511
<211>  248
<212>  PRT
<213>  Homo sapiens

<400>  6511

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Asn Glu Glu Thr Glu Leu Ala Pro 
    130                 135                 140


Ser His Met Ala Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg 
145                 150                 155                 160


Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro 
                165                 170                 175


Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys 
            180                 185                 190


Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Arg Glu Cys Arg 
        195                 200                 205


Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn Arg Val Ala Val 
    210                 215                 220


Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu Lys Ala Leu Lys 
225                 230                 235                 240


Asp Leu Tyr Cys His Lys Val Glu 
                245


<210>  6512
<211>  2515
<212>  DNA
<213>  Homo sapiens

<400>  6512
gataaataaa gaaaacagga aaggaggaaa gcattgatta caaatatctt aacaatgagc     60

aaatgtgcaa ggaaaaaata tattaagaca aatccaagac aaatgaccat ggaaacagtt    120

gaatcccagc atgatggaag tataacagct tctttgacag agagcaagtc tgctcatgtg    180

cagactcaga ctggccaaaa ttcaatccct gctttagctc aggtagcagc aattgcagag    240

acagatgaat ctgcagaatc agaaggtgta attgattctc ataaacgtag agaaatcctt    300

tcacgaagac cctcttatag gaaaatactg aatgaactgt cctctgatgt gcctggtgtt    360

cccaagattg aagaagagag atcagaggaa gaaggaacac cacctagtat tgctaccatg    420

gcagtaccaa ctagcatata tcagactagc acggggcaat acattgctat agcccaaggt    480

ggaacaatcc agatttctaa cccaggatct gatggtgttc agggactgca ggcattaaca    540

atgacaaatt caggagctcc tccaccaggt gctacaattg tacagtacgc agcacaatca    600

gctgatggca cacagcagtt ctttgtccca ggcagccagg ttgttgttca agctgccact    660

ggtgacatgc caacttacca gatccgagct cctactgctg ctttgccaca gggagtggtg    720

atggctgcat cgcccggaag tttgcacagt ccccagcagc tggcagaaga agcaacacgc    780

aaacgagagc tgaggctaat gaaaaacagg gaagctgccc gggagtgtcg caggaagaag    840

aaagaatatg tcaaatgtct tgaaaatcgt gtggctgtgc ttgaaaacca aaacaagact    900

ctcattgagg aactcaaggc cctcaaagat ctttattgcc ataaagtaga gtaactgtct    960

ttgacttgga ccttgtttac tctaatcaag gcaggagatg cagcagtcct acttattgcc   1020

atgtggactt gtgggaagga cacgtgtgac ccttaagaat ccagtttgga ttagtgtttg   1080

aaattgaatt gggaatgttg ttccaggatg tggaatgcag ccgtgatcac acttaccgag   1140

cttactttga tctgtttgtc aatagcatgc aaaaaatgct ttgtttgccc tttgcttctg   1200

ctttttttca gggaagctgc caaagaatgt cgacgtcgaa agaaagaata tgtaaaatgt   1260

ctggagagcc gagttgcagt gctggaagtc cagaacaaga agcttataga ggaacttgaa   1320

accttgaaag acatttgttc tcccaaaaca gattactaga aatatttaac tatgaactga   1380

aggcagcatg tatagttgct tttgaaggaa tacaatatat agctggcaag aatggtggct   1440

tcttttcttt gtatcattca tcttcttctt taatcactta acattcctaa aatgcttcac   1500

tgtacgtagt taagtcgtag ctataacttc aaatttttta aaagagacaa actgtaaaaa   1560

atgtgtgtat tcttaaaatg caatatttgt aaggcttgtt ccaatgccac atacttgcag   1620

ctcccattct atgtgtcatc aatagtgtcc tatgcaataa aattatttgc aggtctttaa   1680

atcattttag gaaaggatga tcaaaaataa tgcatccagc agtacaataa aagtaaacca   1740

caaaaaaata cctcaggaaa gaatagaaag aaagtctatc taatgacatg cctatatgag   1800

aagaatagcc tagatatgaa tatatggcat ttgcagattt ttatattagt tgctttgtta   1860

aaaaaaaaaa gattgtattg ctgtccttga atgccatagt caaagagagt ttttaataga   1920

accatgttgg ttgcactttg tagtgtttgg tgctcattta aatatctgaa catttactac   1980

agtttttaac tctactgtgt aatataaaag atcttgcaga agttcttagt gttggtttaa   2040

tattacctaa tgaaagtgat gacatatttt ttatatctgg aatgagcctg ttgggatcgc   2100

attgcatacc ttcggggtac aagtcagttt ctacactggg tgctgatcct tgcacgcgcc   2160

ctttctacca tctcacggtg gggatggccg cagggctgtg cacccagaag aagatggctg   2220

ttagcgtttc ggccttcata atggcctgag actttctttc tgtaggtggt ctggagctgt   2280

ccggctggtg gccccctatt ttgccattta gcgaacaacc acaggaattt taaaaacaaa   2340

aacatcccaa gattttttca tttcaaaatg cttcaaagtc cacattagat cagatactcc   2400

gctgtcggca cattcagctg aggttcatta caatcgagac tgcaatgtga tctatgtttc   2460

atcttgtttt tataataaaa agcttcaggg aacaagccca aagccctcac cacag        2515


<210>  6513
<211>  299
<212>  PRT
<213>  Homo sapiens

<400>  6513

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly Thr 
    130                 135                 140


Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln Ala 
145                 150                 155                 160


Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val 
                165                 170                 175


Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro 
            180                 185                 190


Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr Tyr 
        195                 200                 205


Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala 
    210                 215                 220


Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala 
225                 230                 235                 240


Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Arg 
                245                 250                 255


Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn Arg 
            260                 265                 270


Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu Lys 
        275                 280                 285


Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
    290                 295


<210>  6514
<211>  2326
<212>  DNA
<213>  Homo sapiens

<400>  6514
gataaataaa gaaaacagga aaggaggaaa gcattgatta caaatatctt aacaatgagc     60

aaatgtgcaa ggaaaaaata tattaagaca aatccaagac aaatgaccat ggaaacagtt    120

gaatcccagc atgatggaag tataacagct tctttgacag agagcaagtc tgctcatgtg    180

cagactcaga ctggccaaaa ttcaatccct gctttagctc aggtagcagc aattgcagag    240

acagatgaat ctgcagaatc agaaggtgta attgattctc ataaacgtag agaaatcctt    300

tcacgaagac cctcttatag gaaaatactg aatgaactgt cctctgatgt gcctggtgtt    360

cccaagattg aagaagagag atcagaggaa gaaggaacac cacctagtat tgctaccatg    420

gcagtaccaa ctagcatata tcagactagc acggggcaat acactgccac tggtgacatg    480

ccaacttacc agatccgagc tcctactgct gctttgccac agggagtggt gatggctgca    540

tcgcccggaa gtttgcacag tccccagcag ctggcagaag aagcaacacg caaacgagag    600

ctgaggctaa tgaaaaacag ggaagctgcc cgggagtgtc gcaggaagaa gaaagaatat    660

gtcaaatgtc ttgaaaatcg tgtggctgtg cttgaaaacc aaaacaagac tctcattgag    720

gaactcaagg ccctcaaaga tctttattgc cataaagtag agtaactgtc tttgacttgg    780

accttgttta ctctaatcaa ggcaggagat gcagcagtcc tacttattgc catgtggact    840

tgtgggaagg acacgtgtga cccttaagaa tccagtttgg attagtgttt gaaattgaat    900

tgggaatgtt gttccaggat gtggaatgca gccgtgatca cacttaccga gcttactttg    960

atctgtttgt caatagcatg caaaaaatgc tttgtttgcc ctttgcttct gctttttttc   1020

agggaagctg ccaaagaatg tcgacgtcga aagaaagaat atgtaaaatg tctggagagc   1080

cgagttgcag tgctggaagt ccagaacaag aagcttatag aggaacttga aaccttgaaa   1140

gacatttgtt ctcccaaaac agattactag aaatatttaa ctatgaactg aaggcagcat   1200

gtatagttgc ttttgaagga atacaatata tagctggcaa gaatggtggc ttcttttctt   1260

tgtatcattc atcttcttct ttaatcactt aacattccta aaatgcttca ctgtacgtag   1320

ttaagtcgta gctataactt caaatttttt aaaagagaca aactgtaaaa aatgtgtgta   1380

ttcttaaaat gcaatatttg taaggcttgt tccaatgcca catacttgca gctcccattc   1440

tatgtgtcat caatagtgtc ctatgcaata aaattatttg caggtcttta aatcatttta   1500

ggaaaggatg atcaaaaata atgcatccag cagtacaata aaagtaaacc acaaaaaaat   1560

acctcaggaa agaatagaaa gaaagtctat ctaatgacat gcctatatga gaagaatagc   1620

ctagatatga atatatggca tttgcagatt tttatattag ttgctttgtt aaaaaaaaaa   1680

agattgtatt gctgtccttg aatgccatag tcaaagagag tttttaatag aaccatgttg   1740

gttgcacttt gtagtgtttg gtgctcattt aaatatctga acatttacta cagtttttaa   1800

ctctactgtg taatataaaa gatcttgcag aagttcttag tgttggttta atattaccta   1860

atgaaagtga tgacatattt tttatatctg gaatgagcct gttgggatcg cattgcatac   1920

cttcggggta caagtcagtt tctacactgg gtgctgatcc ttgcacgcgc cctttctacc   1980

atctcacggt ggggatggcc gcagggctgt gcacccagaa gaagatggct gttagcgttt   2040

cggccttcat aatggcctga gactttcttt ctgtaggtgg tctggagctg tccggctggt   2100

ggccccctat tttgccattt agcgaacaac cacaggaatt ttaaaaacaa aaacatccca   2160

agattttttc atttcaaaat gcttcaaagt ccacattaga tcagatactc cgctgtcggc   2220

acattcagct gaggttcatt acaatcgaga ctgcaatgtg atctatgttt catcttgttt   2280

ttataataaa aagcttcagg gaacaagccc aaagccctca ccacag                  2326


<210>  6515
<211>  236
<212>  PRT
<213>  Homo sapiens

<400>  6515

Met Ser Lys Cys Ala Arg Lys Lys Tyr Ile Lys Thr Asn Pro Arg Gln 
1               5                   10                  15


Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
            20                  25                  30


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
        35                  40                  45


Asn Ser Ile Pro Ala Leu Ala Gln Val Ala Ala Ile Ala Glu Thr Asp 
    50                  55                  60


Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg Glu 
65                  70                  75                  80


Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu Ser 
                85                  90                  95


Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu 
            100                 105                 110


Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser Ile 
        115                 120                 125


Tyr Gln Thr Ser Thr Gly Gln Tyr Thr Ala Thr Gly Asp Met Pro Thr 
    130                 135                 140


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
145                 150                 155                 160


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
                165                 170                 175


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
            180                 185                 190


Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn 
        195                 200                 205


Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu 
    210                 215                 220


Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
225                 230                 235


<210>  6516
<211>  1475
<212>  DNA
<213>  Homo sapiens

<400>  6516
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    900

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    960

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg   1020

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg   1080

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa   1140

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt   1200

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa   1260

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt   1320

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1380

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1440

ttgcttttga aggaatacaa tatatagctg gcaag                              1475


<210>  6517
<211>  332
<212>  PRT
<213>  Homo sapiens

<400>  6517

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn 
    290                 295                 300


Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu 
305                 310                 315                 320


Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                325                 330


<210>  6518
<211>  1321
<212>  DNA
<213>  Homo sapiens

<400>  6518
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    900

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    960

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac   1020

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg   1080

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt   1140

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa   1200

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg   1260

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt   1320

t                                                                   1321


<210>  6519
<211>  333
<212>  PRT
<213>  Homo sapiens

<400>  6519

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser 
    290                 295                 300


Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu 
305                 310                 315                 320


Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                325                 330


<210>  6520
<211>  1723
<212>  DNA
<213>  Homo sapiens

<400>  6520
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    900

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    960

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg   1020

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg   1080

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa   1140

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt   1200

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa   1260

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt   1320

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1380

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1440

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1500

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1560

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1620

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1680

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc ttt                     1723


<210>  6521
<211>  332
<212>  PRT
<213>  Homo sapiens

<400>  6521

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn 
    290                 295                 300


Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu 
305                 310                 315                 320


Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                325                 330


<210>  6522
<211>  2068
<212>  DNA
<213>  Homo sapiens

<400>  6522
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    900

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    960

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg   1020

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg   1080

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa   1140

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt   1200

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa   1260

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt   1320

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1380

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1440

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1500

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1560

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1620

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1680

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc tttaaatcat tttaggaaag   1740

gatgatcaaa aataatgcat ccagcagtac aataaaagta aaccacaaaa aaatacctca   1800

ggaaagaata gaaagaaagt ctatctaatg acatgcctat atgagaagaa tagcctagat   1860

atgaatatat ggcatttgca gatttttata ttagttgctt tgttaaaaaa aaaaagattg   1920

tattgctgtc cttgaatgcc atagtcaaag agagttttta atagaaccat gttggttgca   1980

ctttgtagtg tttggtgctc atttaaatat ctgaacattt actacagttt ttaactctac   2040

tgtgtaatat aaaagatctt gcagaagt                                      2068


<210>  6523
<211>  332
<212>  PRT
<213>  Homo sapiens

<400>  6523

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn 
    290                 295                 300


Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu 
305                 310                 315                 320


Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                325                 330


<210>  6524
<211>  1666
<212>  DNA
<213>  Homo sapiens

<400>  6524
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    900

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    960

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac   1020

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg   1080

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt   1140

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa   1200

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg   1260

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt   1320

taaatcattt taggaaagga tgatcaaaaa taatgcatcc agcagtacaa taaaagtaaa   1380

ccacaaaaaa atacctcagg aaagaataga aagaaagtct atctaatgac atgcctatat   1440

gagaagaata gcctagatat gaatatatgg catttgcaga tttttatatt agttgctttg   1500

ttaaaaaaaa aaagattgta ttgctgtcct tgaatgccat agtcaaagag agtttttaat   1560

agaaccatgt tggttgcact ttgtagtgtt tggtgctcat ttaaatatct gaacatttac   1620

tacagttttt aactctactg tgtaatataa aagatcttgc agaagt                  1666


<210>  6525
<211>  333
<212>  PRT
<213>  Homo sapiens

<400>  6525

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser 
    290                 295                 300


Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu 
305                 310                 315                 320


Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                325                 330


<210>  6526
<211>  2560
<212>  DNA
<213>  Homo sapiens

<400>  6526
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgcccgggag tgtcgcagga agaagaaaga atatgtcaaa    900

tgtcttgaaa atcgtgtggc tgtgcttgaa aaccaaaaca agactctcat tgaggaactc    960

aaggccctca aagatcttta ttgccataaa gtagagtaac tgtctttgac ttggaccttg   1020

tttactctaa tcaaggcagg agatgcagca gtcctactta ttgccatgtg gacttgtggg   1080

aaggacacgt gtgaccctta agaatccagt ttggattagt gtttgaaatt gaattgggaa   1140

tgttgttcca ggatgtggaa tgcagccgtg atcacactta ccgagcttac tttgatctgt   1200

ttgtcaatag catgcaaaaa atgctttgtt tgccctttgc ttctgctttt tttcagggaa   1260

gctgccaaag aatgtcgacg tcgaaagaaa gaatatgtaa aatgtctgga gagccgagtt   1320

gcagtgctgg aagtccagaa caagaagctt atagaggaac ttgaaacctt gaaagacatt   1380

tgttctccca aaacagatta ctagaaatat ttaactatga actgaaggca gcatgtatag   1440

ttgcttttga aggaatacaa tatatagctg gcaagaatgg tggcttcttt tctttgtatc   1500

attcatcttc ttctttaatc acttaacatt cctaaaatgc ttcactgtac gtagttaagt   1560

cgtagctata acttcaaatt ttttaaaaga gacaaactgt aaaaaatgtg tgtattctta   1620

aaatgcaata tttgtaaggc ttgttccaat gccacatact tgcagctccc attctatgtg   1680

tcatcaatag tgtcctatgc aataaaatta tttgcaggtc tttaaatcat tttaggaaag   1740

gatgatcaaa aataatgcat ccagcagtac aataaaagta aaccacaaaa aaatacctca   1800

ggaaagaata gaaagaaagt ctatctaatg acatgcctat atgagaagaa tagcctagat   1860

atgaatatat ggcatttgca gatttttata ttagttgctt tgttaaaaaa aaaaagattg   1920

tattgctgtc cttgaatgcc atagtcaaag agagttttta atagaaccat gttggttgca   1980

ctttgtagtg tttggtgctc atttaaatat ctgaacattt actacagttt ttaactctac   2040

tgtgtaatat aaaagatctt gcagaagttc ttagtgttgg tttaatatta cctaatgaaa   2100

gtgatgacat attttttata tctggaatga gcctgttggg atcgcattgc ataccttcgg   2160

ggtacaagtc agtttctaca ctgggtgctg atccttgcac gcgccctttc taccatctca   2220

cggtggggat ggccgcaggg ctgtgcaccc agaagaagat ggctgttagc gtttcggcct   2280

tcataatggc ctgagacttt ctttctgtag gtggtctgga gctgtccggc tggtggcccc   2340

ctattttgcc atttagcgaa caaccacagg aattttaaaa acaaaaacat cccaagattt   2400

tttcatttca aaatgcttca aagtccacat tagatcagat actccgctgt cggcacattc   2460

agctgaggtt cattacaatc gagactgcaa tgtgatctat gtttcatctt gtttttataa   2520

taaaaagctt cagggaacaa gcccaaagcc ctcaccacag                         2560


<210>  6527
<211>  332
<212>  PRT
<213>  Homo sapiens

<400>  6527

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Arg Glu Cys Arg Arg Lys Lys Lys Glu Tyr Val Lys Cys Leu Glu Asn 
    290                 295                 300


Arg Val Ala Val Leu Glu Asn Gln Asn Lys Thr Leu Ile Glu Glu Leu 
305                 310                 315                 320


Lys Ala Leu Lys Asp Leu Tyr Cys His Lys Val Glu 
                325                 330


<210>  6528
<211>  2158
<212>  DNA
<213>  Homo sapiens

<400>  6528
atgaccatgg aaacagttga atcccagcat gatggaagta taacagcttc tttgacagag     60

agcaagtctg ctcatgtgca gactcagact ggccaaaatt caatccctgc tttagctcag    120

gtttctgtgg ctggatcagg caccagaaga ggctccccag ctgtaactct agtgcagtta    180

ccttcgggcc aaactataca tgtccaggga gtaattcaga caccacagcc atgggttatt    240

cagtcatcag aaatacacac cgttcaggta gcagcaattg cagagacaga tgaatctgca    300

gaatcagaag gtgtaattga ttctcataaa cgtagagaaa tcctttcacg aagaccctct    360

tataggaaaa tactgaatga actgtcctct gatgtgcctg gtgttcccaa gattgaagaa    420

gagagatcag aggaagaagg aacaccacct agtattgcta ccatggcagt accaactagc    480

atatatcaga ctagcacggg gcaatacatt gctatagccc aaggtggaac aatccagatt    540

tctaacccag gatctgatgg tgttcaggga ctgcaggcat taacaatgac aaattcagga    600

gctcctccac caggtgctac aattgtacag tacgcagcac aatcagctga tggcacacag    660

cagttctttg tcccaggcag ccaggttgtt gttcaagctg ccactggtga catgccaact    720

taccagatcc gagctcctac tgctgctttg ccacagggag tggtgatggc tgcatcgccc    780

ggaagtttgc acagtcccca gcagctggca gaagaagcaa cacgcaaacg agagctgagg    840

ctaatgaaaa acagggaagc tgccaaagaa tgtcgacgtc gaaagaaaga atatgtaaaa    900

tgtctggaga gccgagttgc agtgctggaa gtccagaaca agaagcttat agaggaactt    960

gaaaccttga aagacatttg ttctcccaaa acagattact agaaatattt aactatgaac   1020

tgaaggcagc atgtatagtt gcttttgaag gaatacaata tatagctggc aagaatggtg   1080

gcttcttttc tttgtatcat tcatcttctt ctttaatcac ttaacattcc taaaatgctt   1140

cactgtacgt agttaagtcg tagctataac ttcaaatttt ttaaaagaga caaactgtaa   1200

aaaatgtgtg tattcttaaa atgcaatatt tgtaaggctt gttccaatgc cacatacttg   1260

cagctcccat tctatgtgtc atcaatagtg tcctatgcaa taaaattatt tgcaggtctt   1320

taaatcattt taggaaagga tgatcaaaaa taatgcatcc agcagtacaa taaaagtaaa   1380

ccacaaaaaa atacctcagg aaagaataga aagaaagtct atctaatgac atgcctatat   1440

gagaagaata gcctagatat gaatatatgg catttgcaga tttttatatt agttgctttg   1500

ttaaaaaaaa aaagattgta ttgctgtcct tgaatgccat agtcaaagag agtttttaat   1560

agaaccatgt tggttgcact ttgtagtgtt tggtgctcat ttaaatatct gaacatttac   1620

tacagttttt aactctactg tgtaatataa aagatcttgc agaagttctt agtgttggtt   1680

taatattacc taatgaaagt gatgacatat tttttatatc tggaatgagc ctgttgggat   1740

cgcattgcat accttcgggg tacaagtcag tttctacact gggtgctgat ccttgcacgc   1800

gccctttcta ccatctcacg gtggggatgg ccgcagggct gtgcacccag aagaagatgg   1860

ctgttagcgt ttcggccttc ataatggcct gagactttct ttctgtaggt ggtctggagc   1920

tgtccggctg gtggccccct attttgccat ttagcgaaca accacaggaa ttttaaaaac   1980

aaaaacatcc caagattttt tcatttcaaa atgcttcaaa gtccacatta gatcagatac   2040

tccgctgtcg gcacattcag ctgaggttca ttacaatcga gactgcaatg tgatctatgt   2100

ttcatcttgt ttttataata aaaagcttca gggaacaagc ccaaagccct caccacag     2158


<210>  6529
<211>  333
<212>  PRT
<213>  Homo sapiens

<400>  6529

Met Thr Met Glu Thr Val Glu Ser Gln His Asp Gly Ser Ile Thr Ala 
1               5                   10                  15


Ser Leu Thr Glu Ser Lys Ser Ala His Val Gln Thr Gln Thr Gly Gln 
            20                  25                  30


Asn Ser Ile Pro Ala Leu Ala Gln Val Ser Val Ala Gly Ser Gly Thr 
        35                  40                  45


Arg Arg Gly Ser Pro Ala Val Thr Leu Val Gln Leu Pro Ser Gly Gln 
    50                  55                  60


Thr Ile His Val Gln Gly Val Ile Gln Thr Pro Gln Pro Trp Val Ile 
65                  70                  75                  80


Gln Ser Ser Glu Ile His Thr Val Gln Val Ala Ala Ile Ala Glu Thr 
                85                  90                  95


Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg Arg 
            100                 105                 110


Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu Leu 
        115                 120                 125


Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser Glu 
    130                 135                 140


Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr Ser 
145                 150                 155                 160


Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly Gly 
                165                 170                 175


Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu Gln 
            180                 185                 190


Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile 
        195                 200                 205


Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val 
    210                 215                 220


Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr 
225                 230                 235                 240


Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met 
                245                 250                 255


Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu 
            260                 265                 270


Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala 
        275                 280                 285


Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser 
    290                 295                 300


Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu 
305                 310                 315                 320


Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
                325                 330


<210>  6530
<211>  598
<212>  DNA
<213>  Homo sapiens

<400>  6530
agctgaactc tattaaccct atgatgtatg ccaaaagtga ctgactcttc tgaatttctg     60

atggcttcat atttacttgc cacttgtctc atttttcttc agacttgagg attgtaaatt    120

tccatatgtt ttagatttaa acttagttgt gaataaagag gaatttctga cactcacctt    180

ccttgtttat atgatcagat tatcagtaaa cagtgtggga acaaaaggcg taagcagaac    240

gttcagtggg tttgattctt tgcatctaag gtcatttgat actggttgtt ttgattgtcc    300

tggcctttcc agagcttctg ctaatcaaga atatactatg aaaatcatca gagacctagc    360

aactgttgag cttggttttg gctgtcaggc ccctgttctg ctgatggatt gagactcttg    420

ggaattggta acactgccat gaagacctag gtgggtaagg tcattcagat ggagccagtg    480

gaaaggatgt accttaaaac tgactttctg aagtataatt ctccatagct gctgctgaag    540

cctggaggcc tcgactctga aagctaaata actcttcttt ataaatgact acttctca      598


<210>  6531
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  6531

Met Ile Arg Leu Ser Val Asn Ser Val Gly Thr Lys Gly Val Ser Arg 
1               5                   10                  15


Thr Phe Ser Gly Phe Asp Ser Leu His Leu Arg Ser Phe Asp Thr Gly 
            20                  25                  30


Cys Phe Asp Cys Pro Gly Leu Ser Arg Ala Ser Ala Asn Gln Glu Tyr 
        35                  40                  45


Thr Met Lys Ile Ile Arg Asp Leu Ala Thr Val Glu Leu Gly Phe Gly 
    50                  55                  60


Cys Gln Ala Pro Val Leu Leu Met Asp 
65                  70


<210>  6532
<211>  1101
<212>  DNA
<213>  Homo sapiens

<400>  6532
agctacgggt cagagctagt ccactaggtg ctaatcaaat gctgtgttac aacactgtga     60

ggttttccca gttataagtg tcactattag ggtttttttt aattgcaaag ccaaataagg    120

ctgtcaattg catcatctta ccttatttct tcagattaag tactgtttat agtgggattt    180

ttggtggatg tggtggcatc agcataatct atgtttcagg cgtcctatag aagaggatta    240

ttcttcaggg gatgtggaag aaaaggcaca gtctcgctct gtcatccagg ctggagtgcg    300

gtggcatgat ctcagctcac tgcaacctcg aactcctggg ttcaagaaat tctcatgcct    360

cagcctcatg agtagctggg attacaggaa aatactgaat gaactgtcct ctgatgtgcc    420

tggtgttccc aagattgaag aagagagatc agaggaagaa ggaacaccac ctagtattgc    480

taccatggca gtaccaacta gcatatatca gactagcacg gggcaataca gtatgtatgc    540

tgcaattcga tatgatacag tgctagcttt aagtcttctc tagttatatt gaagcaactc    600

aggttttggc attaaattgt tccattttaa aatgcatcat taatacctaa actgtatcat    660

agaatgaaag tatatgttaa aaagtgagat ctttgtattg acagctgtca tataattttg    720

aaaagtaaaa attttgactg ccgaatatag aagaaaattt tggggtaaaa aggagaattt    780

ttcctattta catgtttata ttaatctcta gtaaaacatt gtttttgttg tctttatgat    840

gcatgcgaac ataaatgtct gtatttcatt cttgttggct tttgttaccc acaattacat    900

actattctta ctaatctgag agttttctaa agtatgtttt caatgtttca ctactctcta    960

ctctgttaat ttgtgctaca gtttttccta aaagagaatg gaaaaatgat ttaatttttt   1020

aaactgtagc aattggatag ataattttat ttgaaatttt acacactgaa agctctaaat   1080

aaacagatac attcacattc a                                             1101


<210>  6533
<211>  131
<212>  PRT
<213>  Homo sapiens

<400>  6533

Met Trp Trp His Gln His Asn Leu Cys Phe Arg Arg Pro Ile Glu Glu 
1               5                   10                  15


Asp Tyr Ser Ser Gly Asp Val Glu Glu Lys Ala Gln Ser Arg Ser Val 
            20                  25                  30


Ile Gln Ala Gly Val Arg Trp His Asp Leu Ser Ser Leu Gln Pro Arg 
        35                  40                  45


Thr Pro Gly Phe Lys Lys Phe Ser Cys Leu Ser Leu Met Ser Ser Trp 
    50                  55                  60


Asp Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val 
65                  70                  75                  80


Pro Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser 
                85                  90                  95


Ile Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly 
            100                 105                 110


Gln Tyr Ser Met Tyr Ala Ala Ile Arg Tyr Asp Thr Val Leu Ala Leu 
        115                 120                 125


Ser Leu Leu 
    130


<210>  6534
<211>  650
<212>  DNA
<213>  Homo sapiens

<400>  6534
agctacgggt cagagctagt ccactaggtg ctaatcaaat gctgtgttac aacactgtga     60

ggttttccca gttataagtg tcactattag ggtttttttt aattgcaaag ccaaataagg    120

ctgtcaattg catcatctta ccttatttct tcagattaag tactgtttat agtgggattt    180

ttggtggatg tggtggcatc agcataatct atgtttcagg cgtcctatag aagaggatta    240

ttcttcaggg gatgtggaag aaaaggtagc agcaattgca gagacagatg aatctgcaga    300

atcagaaggt gtaattgatt ctcataaacg tagagaaatc ctttcacgaa gaccctctta    360

taggaaaata ctgaatgaac tgtcctctga tgtgcctggt gttcccaaga ttgaagaaga    420

gagatcagag gaagaaggaa caccacctag tattgctacc atggcagtac caactagcat    480

atatcagact agcacggggc aatacattgc tatagcccaa ggtggaacaa tccagatttc    540

taacccagga tctgatggtg ttcagggact gcaggcatta acaatgacaa attcaggagc    600

tcctccacca ggtgctacaa ttgtacagta cgcagcacaa tcagctgatg               650


<210>  6535
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  6535

Met Trp Trp His Gln His Asn Leu Cys Phe Arg Arg Pro Ile Glu Glu 
1               5                   10                  15


Asp Tyr Ser Ser Gly Asp Val Glu Glu Lys Val Ala Ala Ile Ala Glu 
            20                  25                  30


Thr Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg 
        35                  40                  45


Arg Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu 
    50                  55                  60


Leu Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser 
65                  70                  75                  80


Glu Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr 
                85                  90                  95


Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly 
            100                 105                 110


Gly Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu 
        115                 120                 125


Gln Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr 
    130                 135                 140


Ile Val Gln Tyr Ala Ala Gln Ser Ala 
145                 150


<210>  6536
<211>  2156
<212>  DNA
<213>  Homo sapiens

<400>  6536
agctacgggt cagagctagt ccactaggtg ctaatcaaat gctgtgttac aacactgtga     60

ggttttccca gttataagtg tcactattag ggtttttttt aattgcaaag ccaaataagg    120

ctgtcaattg catcatctta ccttatttct tcagattaag tactgtttat agtgggattt    180

ttggtggatg tggtggcatc agcataatct atgtttcagg cgtcctatag aagaggatta    240

ttcttcaggg gatgtggaag aaaaggtagc agcaattgca gagacagatg aatctgcaga    300

atcagaaggt gtaattgatt ctcataaacg tagagaaatc ctttcacgaa gaccctctta    360

taggaaaata ctgaatgaac tgtcctctga tgtgcctggt gttcccaaga ttgaagaaga    420

gagatcagag gaagaaggaa caccacctag tattgctacc atggcagtac caactagcat    480

atatcagact agcacggggc aatacattgc tatagcccaa ggtggaacaa tccagatttc    540

taacccagga tctgatggtg ttcagggact gcaggcatta acaatgacaa attcaggagc    600

tcctccacca ggtgctacaa ttgtacagta cgcagcacaa tcagctgatg gcacacagca    660

gttctttgtc ccaggcagcc aggttgttgt tcaagctgcc actggtgaca tgccaactta    720

ccagatccga gctcctactg ctgctttgcc acagggagtg gtgatggctg catcgcccgg    780

aagtttgcac agtccccagc agctggcaga agaagcaaca cgcaaacgag agctgaggct    840

aatgaaaaac agggaagctg ccaaagaatg tcgacgtcga aagaaagaat atgtaaaatg    900

tctggagagc cgagttgcag tgctggaagt ccagaacaag aagcttatag aggaacttga    960

aaccttgaaa gacatttgtt ctcccaaaac agattactag aaatatttaa ctatgaactg   1020

aaggcagcat gtatagttgc ttttgaagga atacaatata tagctggcaa gaatggtggc   1080

ttcttttctt tgtatcattc atcttcttct ttaatcactt aacattccta aaatgcttca   1140

ctgtacgtag ttaagtcgta gctataactt caaatttttt aaaagagaca aactgtaaaa   1200

aatgtgtgta ttcttaaaat gcaatatttg taaggcttgt tccaatgcca catacttgca   1260

gctcccattc tatgtgtcat caatagtgtc ctatgcaata aaattatttg caggtcttta   1320

aatcatttta ggaaaggatg atcaaaaata atgcatccag cagtacaata aaagtaaacc   1380

acaaaaaaat acctcaggaa agaatagaaa gaaagtctat ctaatgacat gcctatatga   1440

gaagaatagc ctagatatga atatatggca tttgcagatt tttatattag ttgctttgtt   1500

aaaaaaaaaa agattgtatt gctgtccttg aatgccatag tcaaagagag tttttaatag   1560

aaccatgttg gttgcacttt gtagtgtttg gtgctcattt aaatatctga acatttacta   1620

cagtttttaa ctctactgtg taatataaaa gatcttgcag aagttcttag tgttggttta   1680

atattaccta atgaaagtga tgacatattt tttatatctg gaatgagcct gttgggatcg   1740

cattgcatac cttcggggta caagtcagtt tctacactgg gtgctgatcc ttgcacgcgc   1800

cctttctacc atctcacggt ggggatggcc gcagggctgt gcacccagaa gaagatggct   1860

gttagcgttt cggccttcat aatggcctga gactttcttt ctgtaggtgg tctggagctg   1920

tccggctggt ggccccctat tttgccattt agcgaacaac cacaggaatt ttaaaaacaa   1980

aaacatccca agattttttc atttcaaaat gcttcaaagt ccacattaga tcagatactc   2040

cgctgtcggc acattcagct gaggttcatt acaatcgaga ctgcaatgtg atctatgttt   2100

catcttgttt ttataataaa aagcttcagg gaacaagccc aaagccctca ccacag       2156


<210>  6537
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  6537

Met Trp Trp His Gln His Asn Leu Cys Phe Arg Arg Pro Ile Glu Glu 
1               5                   10                  15


Asp Tyr Ser Ser Gly Asp Val Glu Glu Lys Val Ala Ala Ile Ala Glu 
            20                  25                  30


Thr Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg 
        35                  40                  45


Arg Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu 
    50                  55                  60


Leu Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser 
65                  70                  75                  80


Glu Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr 
                85                  90                  95


Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Ile Ala Ile Ala Gln Gly 
            100                 105                 110


Gly Thr Ile Gln Ile Ser Asn Pro Gly Ser Asp Gly Val Gln Gly Leu 
        115                 120                 125


Gln Ala Leu Thr Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr 
    130                 135                 140


Ile Val Gln Tyr Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe 
145                 150                 155                 160


Val Pro Gly Ser Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro 
                165                 170                 175


Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val 
            180                 185                 190


Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu 
        195                 200                 205


Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala 
    210                 215                 220


Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu 
225                 230                 235                 240


Ser Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu 
                245                 250                 255


Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
            260                 265                 270


<210>  6538
<211>  1967
<212>  DNA
<213>  Homo sapiens

<400>  6538
agctacgggt cagagctagt ccactaggtg ctaatcaaat gctgtgttac aacactgtga     60

ggttttccca gttataagtg tcactattag ggtttttttt aattgcaaag ccaaataagg    120

ctgtcaattg catcatctta ccttatttct tcagattaag tactgtttat agtgggattt    180

ttggtggatg tggtggcatc agcataatct atgtttcagg cgtcctatag aagaggatta    240

ttcttcaggg gatgtggaag aaaaggtagc agcaattgca gagacagatg aatctgcaga    300

atcagaaggt gtaattgatt ctcataaacg tagagaaatc ctttcacgaa gaccctctta    360

taggaaaata ctgaatgaac tgtcctctga tgtgcctggt gttcccaaga ttgaagaaga    420

gagatcagag gaagaaggaa caccacctag tattgctacc atggcagtac caactagcat    480

atatcagact agcacggggc aatacactgc cactggtgac atgccaactt accagatccg    540

agctcctact gctgctttgc cacagggagt ggtgatggct gcatcgcccg gaagtttgca    600

cagtccccag cagctggcag aagaagcaac acgcaaacga gagctgaggc taatgaaaaa    660

cagggaagct gccaaagaat gtcgacgtcg aaagaaagaa tatgtaaaat gtctggagag    720

ccgagttgca gtgctggaag tccagaacaa gaagcttata gaggaacttg aaaccttgaa    780

agacatttgt tctcccaaaa cagattacta gaaatattta actatgaact gaaggcagca    840

tgtatagttg cttttgaagg aatacaatat atagctggca agaatggtgg cttcttttct    900

ttgtatcatt catcttcttc tttaatcact taacattcct aaaatgcttc actgtacgta    960

gttaagtcgt agctataact tcaaattttt taaaagagac aaactgtaaa aaatgtgtgt   1020

attcttaaaa tgcaatattt gtaaggcttg ttccaatgcc acatacttgc agctcccatt   1080

ctatgtgtca tcaatagtgt cctatgcaat aaaattattt gcaggtcttt aaatcatttt   1140

aggaaaggat gatcaaaaat aatgcatcca gcagtacaat aaaagtaaac cacaaaaaaa   1200

tacctcagga aagaatagaa agaaagtcta tctaatgaca tgcctatatg agaagaatag   1260

cctagatatg aatatatggc atttgcagat ttttatatta gttgctttgt taaaaaaaaa   1320

aagattgtat tgctgtcctt gaatgccata gtcaaagaga gtttttaata gaaccatgtt   1380

ggttgcactt tgtagtgttt ggtgctcatt taaatatctg aacatttact acagttttta   1440

actctactgt gtaatataaa agatcttgca gaagttctta gtgttggttt aatattacct   1500

aatgaaagtg atgacatatt ttttatatct ggaatgagcc tgttgggatc gcattgcata   1560

ccttcggggt acaagtcagt ttctacactg ggtgctgatc cttgcacgcg ccctttctac   1620

catctcacgg tggggatggc cgcagggctg tgcacccaga agaagatggc tgttagcgtt   1680

tcggccttca taatggcctg agactttctt tctgtaggtg gtctggagct gtccggctgg   1740

tggcccccta ttttgccatt tagcgaacaa ccacaggaat tttaaaaaca aaaacatccc   1800

aagatttttt catttcaaaa tgcttcaaag tccacattag atcagatact ccgctgtcgg   1860

cacattcagc tgaggttcat tacaatcgag actgcaatgt gatctatgtt tcatcttgtt   1920

tttataataa aaagcttcag ggaacaagcc caaagccctc accacag                 1967


<210>  6539
<211>  207
<212>  PRT
<213>  Homo sapiens

<400>  6539

Met Trp Trp His Gln His Asn Leu Cys Phe Arg Arg Pro Ile Glu Glu 
1               5                   10                  15


Asp Tyr Ser Ser Gly Asp Val Glu Glu Lys Val Ala Ala Ile Ala Glu 
            20                  25                  30


Thr Asp Glu Ser Ala Glu Ser Glu Gly Val Ile Asp Ser His Lys Arg 
        35                  40                  45


Arg Glu Ile Leu Ser Arg Arg Pro Ser Tyr Arg Lys Ile Leu Asn Glu 
    50                  55                  60


Leu Ser Ser Asp Val Pro Gly Val Pro Lys Ile Glu Glu Glu Arg Ser 
65                  70                  75                  80


Glu Glu Glu Gly Thr Pro Pro Ser Ile Ala Thr Met Ala Val Pro Thr 
                85                  90                  95


Ser Ile Tyr Gln Thr Ser Thr Gly Gln Tyr Thr Ala Thr Gly Asp Met 
            100                 105                 110


Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val 
        115                 120                 125


Val Met Ala Ala Ser Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala 
    130                 135                 140


Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu 
145                 150                 155                 160


Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu 
                165                 170                 175


Glu Ser Arg Val Ala Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu 
            180                 185                 190


Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
        195                 200                 205


<210>  6540
<211>  919
<212>  DNA
<213>  Homo sapiens

<400>  6540
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atggtagcag    120

caattgcaga gacagatgaa tctgcagaat cagaaggtgt aattgattct cataaacgta    180

gagaaatcct ttcacgaaga ccctcttata ggaaaatact gaatgaactg tcctctgatg    240

tgcctggtgt tcccaagatt gaagaagaga gatcagagga agaaggaaca ccacctagta    300

ttgctaccat ggcagtacca actagcatat atcagactag cacggggcaa tacattgcta    360

tagcccaagg tggaacaatc cagatttcta acccaggatc tgatggtgtt cagggactgc    420

aggcattaac aatgacaaat tcaggagctc ctccaccagg tgctacaatt gtacagtacg    480

cagcacaatc agctgatggc acacagcagt tctttgtccc aggcagccag gttgttgttc    540

aagctgccac tggtgacatg ccaacttacc agatccgagc tcctactgct gctttgccac    600

agggagtggt gatggctgca tcgcccggaa gtttgcacag tccccagcag ctggcagaag    660

aagcaacacg caaacgagag ctgaggctaa tgaaaaacag ggaagctgcc aaagaatgtc    720

gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg agttgcagtg ctggaagtcc    780

agaacaagaa gcttatagag gaacttgaaa ccttgaaaga catttgttct cccaaaacag    840

attactagaa atatttaact atgaactgaa ggcagcatgt atagttgctt ttgaaggaat    900

acaatatata gctggcaag                                                 919


<210>  6541
<211>  245
<212>  PRT
<213>  Homo sapiens

<400>  6541

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile Ser Asn Pro Gly 
                85                  90                  95


Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr Met Thr Asn Ser Gly 
            100                 105                 110


Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr Ala Ala Gln Ser Ala 
        115                 120                 125


Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser Gln Val Val Val Gln 
    130                 135                 140


Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala 
145                 150                 155                 160


Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His 
                165                 170                 175


Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg 
            180                 185                 190


Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys 
        195                 200                 205


Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln 
    210                 215                 220


Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser 
225                 230                 235                 240


Pro Lys Thr Asp Tyr 
                245


<210>  6542
<211>  926
<212>  DNA
<213>  Homo sapiens

<400>  6542
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atgttgctat    120

agcccaaggt ggaacaatcc agatttctaa cccaggatct gatggtgttc agggactgca    180

ggcattaaca atgacaaatt caggagctcc tccaccaggt gctacaattg tacagtacgc    240

agcacaatca gctgatggca cacagcagtt ctttgtccca ggcagccagg ttgttgttca    300

agctgccact ggtgacatgc caacttacca gatccgagct cctactgctg ctttgccaca    360

gggagtggtg atggctgcat cgcccggaag tttgcacagt ccccagcagc tggcagaaga    420

agcaacacgc aaacgagagc tgaggctaat gaaaaacagg gaagctgcca aagaatgtcg    480

acgtcgaaag aaagaatatg taaaatgtct ggagagccga gttgcagtgc tggaagtcca    540

gaacaagaag cttatagagg aacttgaaac cttgaaagac atttgttctc ccaaaacaga    600

ttactagaaa tatttaacta tgaactgaag gcagcatgta tagttgcttt tgaaggaata    660

caatatatag ctggcaagaa tggtggcttc ttttctttgt atcattcatc ttcttcttta    720

atcacttaac attcctaaaa tgcttcactg tacgtagtta agtcgtagct ataacttcaa    780

attttttaaa agagacaaac tgtaaaaaat gtgtgtattc ttaaaatgca atatttgtaa    840

ggcttgttcc aatgccacat acttgcagct cccattctat gtgtcatcaa tagtgtccta    900

tgcaataaaa ttatttgcag gtcttt                                         926


<210>  6543
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  6543

Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr 
1               5                   10                  15


Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser 
            20                  25                  30


Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile 
        35                  40                  45


Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser 
    50                  55                  60


Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg 
65                  70                  75                  80


Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys 
                85                  90                  95


Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala 
            100                 105                 110


Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu 
        115                 120                 125


Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
    130                 135


<210>  6544
<211>  1167
<212>  DNA
<213>  Homo sapiens

<400>  6544
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atggtagcag    120

caattgcaga gacagatgaa tctgcagaat cagaaggtgt aattgattct cataaacgta    180

gagaaatcct ttcacgaaga ccctcttata ggaaaatact gaatgaactg tcctctgatg    240

tgcctggtgt tcccaagatt gaagaagaga gatcagagga agaaggaaca ccacctagta    300

ttgctaccat ggcagtacca actagcatat atcagactag cacggggcaa tacattgcta    360

tagcccaagg tggaacaatc cagatttcta acccaggatc tgatggtgtt cagggactgc    420

aggcattaac aatgacaaat tcaggagctc ctccaccagg tgctacaatt gtacagtacg    480

cagcacaatc agctgatggc acacagcagt tctttgtccc aggcagccag gttgttgttc    540

aagctgccac tggtgacatg ccaacttacc agatccgagc tcctactgct gctttgccac    600

agggagtggt gatggctgca tcgcccggaa gtttgcacag tccccagcag ctggcagaag    660

aagcaacacg caaacgagag ctgaggctaa tgaaaaacag ggaagctgcc aaagaatgtc    720

gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg agttgcagtg ctggaagtcc    780

agaacaagaa gcttatagag gaacttgaaa ccttgaaaga catttgttct cccaaaacag    840

attactagaa atatttaact atgaactgaa ggcagcatgt atagttgctt ttgaaggaat    900

acaatatata gctggcaaga atggtggctt cttttctttg tatcattcat cttcttcttt    960

aatcacttaa cattcctaaa atgcttcact gtacgtagtt aagtcgtagc tataacttca   1020

aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt cttaaaatgc aatatttgta   1080

aggcttgttc caatgccaca tacttgcagc tcccattcta tgtgtcatca atagtgtcct   1140

atgcaataaa attatttgca ggtcttt                                       1167


<210>  6545
<211>  245
<212>  PRT
<213>  Homo sapiens

<400>  6545

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile Ser Asn Pro Gly 
                85                  90                  95


Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr Met Thr Asn Ser Gly 
            100                 105                 110


Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr Ala Ala Gln Ser Ala 
        115                 120                 125


Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser Gln Val Val Val Gln 
    130                 135                 140


Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala 
145                 150                 155                 160


Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His 
                165                 170                 175


Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg 
            180                 185                 190


Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys 
        195                 200                 205


Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln 
    210                 215                 220


Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser 
225                 230                 235                 240


Pro Lys Thr Asp Tyr 
                245


<210>  6546
<211>  1271
<212>  DNA
<213>  Homo sapiens

<400>  6546
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atgttgctat    120

agcccaaggt ggaacaatcc agatttctaa cccaggatct gatggtgttc agggactgca    180

ggcattaaca atgacaaatt caggagctcc tccaccaggt gctacaattg tacagtacgc    240

agcacaatca gctgatggca cacagcagtt ctttgtccca ggcagccagg ttgttgttca    300

agctgccact ggtgacatgc caacttacca gatccgagct cctactgctg ctttgccaca    360

gggagtggtg atggctgcat cgcccggaag tttgcacagt ccccagcagc tggcagaaga    420

agcaacacgc aaacgagagc tgaggctaat gaaaaacagg gaagctgcca aagaatgtcg    480

acgtcgaaag aaagaatatg taaaatgtct ggagagccga gttgcagtgc tggaagtcca    540

gaacaagaag cttatagagg aacttgaaac cttgaaagac atttgttctc ccaaaacaga    600

ttactagaaa tatttaacta tgaactgaag gcagcatgta tagttgcttt tgaaggaata    660

caatatatag ctggcaagaa tggtggcttc ttttctttgt atcattcatc ttcttcttta    720

atcacttaac attcctaaaa tgcttcactg tacgtagtta agtcgtagct ataacttcaa    780

attttttaaa agagacaaac tgtaaaaaat gtgtgtattc ttaaaatgca atatttgtaa    840

ggcttgttcc aatgccacat acttgcagct cccattctat gtgtcatcaa tagtgtccta    900

tgcaataaaa ttatttgcag gtctttaaat cattttagga aaggatgatc aaaaataatg    960

catccagcag tacaataaaa gtaaaccaca aaaaaatacc tcaggaaaga atagaaagaa   1020

agtctatcta atgacatgcc tatatgagaa gaatagccta gatatgaata tatggcattt   1080

gcagattttt atattagttg ctttgttaaa aaaaaaaaga ttgtattgct gtccttgaat   1140

gccatagtca aagagagttt ttaatagaac catgttggtt gcactttgta gtgtttggtg   1200

ctcatttaaa tatctgaaca tttactacag tttttaactc tactgtgtaa tataaaagat   1260

cttgcagaag t                                                        1271


<210>  6547
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  6547

Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr 
1               5                   10                  15


Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser 
            20                  25                  30


Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile 
        35                  40                  45


Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser 
    50                  55                  60


Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg 
65                  70                  75                  80


Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys 
                85                  90                  95


Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala 
            100                 105                 110


Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu 
        115                 120                 125


Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
    130                 135


<210>  6548
<211>  1512
<212>  DNA
<213>  Homo sapiens

<400>  6548
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atggtagcag    120

caattgcaga gacagatgaa tctgcagaat cagaaggtgt aattgattct cataaacgta    180

gagaaatcct ttcacgaaga ccctcttata ggaaaatact gaatgaactg tcctctgatg    240

tgcctggtgt tcccaagatt gaagaagaga gatcagagga agaaggaaca ccacctagta    300

ttgctaccat ggcagtacca actagcatat atcagactag cacggggcaa tacattgcta    360

tagcccaagg tggaacaatc cagatttcta acccaggatc tgatggtgtt cagggactgc    420

aggcattaac aatgacaaat tcaggagctc ctccaccagg tgctacaatt gtacagtacg    480

cagcacaatc agctgatggc acacagcagt tctttgtccc aggcagccag gttgttgttc    540

aagctgccac tggtgacatg ccaacttacc agatccgagc tcctactgct gctttgccac    600

agggagtggt gatggctgca tcgcccggaa gtttgcacag tccccagcag ctggcagaag    660

aagcaacacg caaacgagag ctgaggctaa tgaaaaacag ggaagctgcc aaagaatgtc    720

gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg agttgcagtg ctggaagtcc    780

agaacaagaa gcttatagag gaacttgaaa ccttgaaaga catttgttct cccaaaacag    840

attactagaa atatttaact atgaactgaa ggcagcatgt atagttgctt ttgaaggaat    900

acaatatata gctggcaaga atggtggctt cttttctttg tatcattcat cttcttcttt    960

aatcacttaa cattcctaaa atgcttcact gtacgtagtt aagtcgtagc tataacttca   1020

aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt cttaaaatgc aatatttgta   1080

aggcttgttc caatgccaca tacttgcagc tcccattcta tgtgtcatca atagtgtcct   1140

atgcaataaa attatttgca ggtctttaaa tcattttagg aaaggatgat caaaaataat   1200

gcatccagca gtacaataaa agtaaaccac aaaaaaatac ctcaggaaag aatagaaaga   1260

aagtctatct aatgacatgc ctatatgaga agaatagcct agatatgaat atatggcatt   1320

tgcagatttt tatattagtt gctttgttaa aaaaaaaaag attgtattgc tgtccttgaa   1380

tgccatagtc aaagagagtt tttaatagaa ccatgttggt tgcactttgt agtgtttggt   1440

gctcatttaa atatctgaac atttactaca gtttttaact ctactgtgta atataaaaga   1500

tcttgcagaa gt                                                       1512


<210>  6549
<211>  245
<212>  PRT
<213>  Homo sapiens

<400>  6549

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile Ser Asn Pro Gly 
                85                  90                  95


Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr Met Thr Asn Ser Gly 
            100                 105                 110


Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr Ala Ala Gln Ser Ala 
        115                 120                 125


Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser Gln Val Val Val Gln 
    130                 135                 140


Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala 
145                 150                 155                 160


Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His 
                165                 170                 175


Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg 
            180                 185                 190


Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys 
        195                 200                 205


Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln 
    210                 215                 220


Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser 
225                 230                 235                 240


Pro Lys Thr Asp Tyr 
                245


<210>  6550
<211>  1763
<212>  DNA
<213>  Homo sapiens

<400>  6550
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atgttgctat    120

agcccaaggt ggaacaatcc agatttctaa cccaggatct gatggtgttc agggactgca    180

ggcattaaca atgacaaatt caggagctcc tccaccaggt gctacaattg tacagtacgc    240

agcacaatca gctgatggca cacagcagtt ctttgtccca ggcagccagg ttgttgttca    300

agctgccact ggtgacatgc caacttacca gatccgagct cctactgctg ctttgccaca    360

gggagtggtg atggctgcat cgcccggaag tttgcacagt ccccagcagc tggcagaaga    420

agcaacacgc aaacgagagc tgaggctaat gaaaaacagg gaagctgcca aagaatgtcg    480

acgtcgaaag aaagaatatg taaaatgtct ggagagccga gttgcagtgc tggaagtcca    540

gaacaagaag cttatagagg aacttgaaac cttgaaagac atttgttctc ccaaaacaga    600

ttactagaaa tatttaacta tgaactgaag gcagcatgta tagttgcttt tgaaggaata    660

caatatatag ctggcaagaa tggtggcttc ttttctttgt atcattcatc ttcttcttta    720

atcacttaac attcctaaaa tgcttcactg tacgtagtta agtcgtagct ataacttcaa    780

attttttaaa agagacaaac tgtaaaaaat gtgtgtattc ttaaaatgca atatttgtaa    840

ggcttgttcc aatgccacat acttgcagct cccattctat gtgtcatcaa tagtgtccta    900

tgcaataaaa ttatttgcag gtctttaaat cattttagga aaggatgatc aaaaataatg    960

catccagcag tacaataaaa gtaaaccaca aaaaaatacc tcaggaaaga atagaaagaa   1020

agtctatcta atgacatgcc tatatgagaa gaatagccta gatatgaata tatggcattt   1080

gcagattttt atattagttg ctttgttaaa aaaaaaaaga ttgtattgct gtccttgaat   1140

gccatagtca aagagagttt ttaatagaac catgttggtt gcactttgta gtgtttggtg   1200

ctcatttaaa tatctgaaca tttactacag tttttaactc tactgtgtaa tataaaagat   1260

cttgcagaag ttcttagtgt tggtttaata ttacctaatg aaagtgatga catatttttt   1320

atatctggaa tgagcctgtt gggatcgcat tgcatacctt cggggtacaa gtcagtttct   1380

acactgggtg ctgatccttg cacgcgccct ttctaccatc tcacggtggg gatggccgca   1440

gggctgtgca cccagaagaa gatggctgtt agcgtttcgg ccttcataat ggcctgagac   1500

tttctttctg taggtggtct ggagctgtcc ggctggtggc cccctatttt gccatttagc   1560

gaacaaccac aggaatttta aaaacaaaaa catcccaaga ttttttcatt tcaaaatgct   1620

tcaaagtcca cattagatca gatactccgc tgtcggcaca ttcagctgag gttcattaca   1680

atcgagactg caatgtgatc tatgtttcat cttgttttta taataaaaag cttcagggaa   1740

caagcccaaa gccctcacca cag                                           1763


<210>  6551
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  6551

Met Thr Asn Ser Gly Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr 
1               5                   10                  15


Ala Ala Gln Ser Ala Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser 
            20                  25                  30


Gln Val Val Val Gln Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile 
        35                  40                  45


Arg Ala Pro Thr Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser 
    50                  55                  60


Pro Gly Ser Leu His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg 
65                  70                  75                  80


Lys Arg Glu Leu Arg Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys 
                85                  90                  95


Arg Arg Arg Lys Lys Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala 
            100                 105                 110


Val Leu Glu Val Gln Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu 
        115                 120                 125


Lys Asp Ile Cys Ser Pro Lys Thr Asp Tyr 
    130                 135


<210>  6552
<211>  2004
<212>  DNA
<213>  Homo sapiens

<400>  6552
ggaacattct tagccaccga agtatgggca ccaaaagcga taaggagcat gtgttcctta     60

ataaatgtca catcagaaaa tgactgttcc aggacagtaa ccacctcccg atggtagcag    120

caattgcaga gacagatgaa tctgcagaat cagaaggtgt aattgattct cataaacgta    180

gagaaatcct ttcacgaaga ccctcttata ggaaaatact gaatgaactg tcctctgatg    240

tgcctggtgt tcccaagatt gaagaagaga gatcagagga agaaggaaca ccacctagta    300

ttgctaccat ggcagtacca actagcatat atcagactag cacggggcaa tacattgcta    360

tagcccaagg tggaacaatc cagatttcta acccaggatc tgatggtgtt cagggactgc    420

aggcattaac aatgacaaat tcaggagctc ctccaccagg tgctacaatt gtacagtacg    480

cagcacaatc agctgatggc acacagcagt tctttgtccc aggcagccag gttgttgttc    540

aagctgccac tggtgacatg ccaacttacc agatccgagc tcctactgct gctttgccac    600

agggagtggt gatggctgca tcgcccggaa gtttgcacag tccccagcag ctggcagaag    660

aagcaacacg caaacgagag ctgaggctaa tgaaaaacag ggaagctgcc aaagaatgtc    720

gacgtcgaaa gaaagaatat gtaaaatgtc tggagagccg agttgcagtg ctggaagtcc    780

agaacaagaa gcttatagag gaacttgaaa ccttgaaaga catttgttct cccaaaacag    840

attactagaa atatttaact atgaactgaa ggcagcatgt atagttgctt ttgaaggaat    900

acaatatata gctggcaaga atggtggctt cttttctttg tatcattcat cttcttcttt    960

aatcacttaa cattcctaaa atgcttcact gtacgtagtt aagtcgtagc tataacttca   1020

aattttttaa aagagacaaa ctgtaaaaaa tgtgtgtatt cttaaaatgc aatatttgta   1080

aggcttgttc caatgccaca tacttgcagc tcccattcta tgtgtcatca atagtgtcct   1140

atgcaataaa attatttgca ggtctttaaa tcattttagg aaaggatgat caaaaataat   1200

gcatccagca gtacaataaa agtaaaccac aaaaaaatac ctcaggaaag aatagaaaga   1260

aagtctatct aatgacatgc ctatatgaga agaatagcct agatatgaat atatggcatt   1320

tgcagatttt tatattagtt gctttgttaa aaaaaaaaag attgtattgc tgtccttgaa   1380

tgccatagtc aaagagagtt tttaatagaa ccatgttggt tgcactttgt agtgtttggt   1440

gctcatttaa atatctgaac atttactaca gtttttaact ctactgtgta atataaaaga   1500

tcttgcagaa gttcttagtg ttggtttaat attacctaat gaaagtgatg acatattttt   1560

tatatctgga atgagcctgt tgggatcgca ttgcatacct tcggggtaca agtcagtttc   1620

tacactgggt gctgatcctt gcacgcgccc tttctaccat ctcacggtgg ggatggccgc   1680

agggctgtgc acccagaaga agatggctgt tagcgtttcg gccttcataa tggcctgaga   1740

ctttctttct gtaggtggtc tggagctgtc cggctggtgg ccccctattt tgccatttag   1800

cgaacaacca caggaatttt aaaaacaaaa acatcccaag attttttcat ttcaaaatgc   1860

ttcaaagtcc acattagatc agatactccg ctgtcggcac attcagctga ggttcattac   1920

aatcgagact gcaatgtgat ctatgtttca tcttgttttt ataataaaaa gcttcaggga   1980

acaagcccaa agccctcacc acag                                          2004


<210>  6553
<211>  245
<212>  PRT
<213>  Homo sapiens

<400>  6553

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile Ser Asn Pro Gly 
                85                  90                  95


Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr Met Thr Asn Ser Gly 
            100                 105                 110


Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr Ala Ala Gln Ser Ala 
        115                 120                 125


Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser Gln Val Val Val Gln 
    130                 135                 140


Ala Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr Ala 
145                 150                 155                 160


Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu His 
                165                 170                 175


Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu Arg 
            180                 185                 190


Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys Lys 
        195                 200                 205


Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val Gln 
    210                 215                 220


Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys Ser 
225                 230                 235                 240


Pro Lys Thr Asp Tyr 
                245


<210>  6554
<211>  1812
<212>  DNA
<213>  Homo sapiens

<400>  6554
acattcttag ccaccgaagt atgggcacca aaagcgataa ggagcatgtg ttccttaata     60

aatgtcacat cagaaaatga ctgttccagg acagtaacca cctcccgatg gtagcagcaa    120

ttgcagagac agatgaatct gcagaatcag aaggtgtaat tgattctcat aaacgtagag    180

aaatcctttc acgaagaccc tcttatagga aaatactgaa tgaactgtcc tctgatgtgc    240

ctggtgttcc caagattgaa gaagagagat cagaggaaga aggaacacca cctagtattg    300

ctaccatggc agtaccaact agcatatatc agactagcac ggggcaatac actgccactg    360

gtgacatgcc aacttaccag atccgagctc ctactgctgc tttgccacag ggagtggtga    420

tggctgcatc gcccggaagt ttgcacagtc cccagcagct ggcagaagaa gcaacacgca    480

aacgagagct gaggctaatg aaaaacaggg aagctgccaa agaatgtcga cgtcgaaaga    540

aagaatatgt aaaatgtctg gagagccgag ttgcagtgct ggaagtccag aacaagaagc    600

ttatagagga acttgaaacc ttgaaagaca tttgttctcc caaaacagat tactagaaat    660

atttaactat gaactgaagg cagcatgtat agttgctttt gaaggaatac aatatatagc    720

tggcaagaat ggtggcttct tttctttgta tcattcatct tcttctttaa tcacttaaca    780

ttcctaaaat gcttcactgt acgtagttaa gtcgtagcta taacttcaaa ttttttaaaa    840

gagacaaact gtaaaaaatg tgtgtattct taaaatgcaa tatttgtaag gcttgttcca    900

atgccacata cttgcagctc ccattctatg tgtcatcaat agtgtcctat gcaataaaat    960

tatttgcagg tctttaaatc attttaggaa aggatgatca aaaataatgc atccagcagt   1020

acaataaaag taaaccacaa aaaaatacct caggaaagaa tagaaagaaa gtctatctaa   1080

tgacatgcct atatgagaag aatagcctag atatgaatat atggcatttg cagattttta   1140

tattagttgc tttgttaaaa aaaaaaagat tgtattgctg tccttgaatg ccatagtcaa   1200

agagagtttt taatagaacc atgttggttg cactttgtag tgtttggtgc tcatttaaat   1260

atctgaacat ttactacagt ttttaactct actgtgtaat ataaaagatc ttgcagaagt   1320

tcttagtgtt ggtttaatat tacctaatga aagtgatgac atatttttta tatctggaat   1380

gagcctgttg ggatcgcatt gcataccttc ggggtacaag tcagtttcta cactgggtgc   1440

tgatccttgc acgcgccctt tctaccatct cacggtgggg atggccgcag ggctgtgcac   1500

ccagaagaag atggctgtta gcgtttcggc cttcataatg gcctgagact ttctttctgt   1560

aggtggtctg gagctgtccg gctggtggcc ccctattttg ccatttagcg aacaaccaca   1620

ggaattttaa aaacaaaaac atcccaagat tttttcattt caaaatgctt caaagtccac   1680

attagatcag atactccgct gtcggcacat tcagctgagg ttcattacaa tcgagactgc   1740

aatgtgatct atgtttcatc ttgtttttat aataaaaagc ttcagggaac aagcccaaag   1800

ccctcaccac ag                                                       1812


<210>  6555
<211>  182
<212>  PRT
<213>  Homo sapiens

<400>  6555

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Thr Ala Thr Gly Asp Met Pro Thr Tyr Gln Ile Arg Ala Pro Thr 
                85                  90                  95


Ala Ala Leu Pro Gln Gly Val Val Met Ala Ala Ser Pro Gly Ser Leu 
            100                 105                 110


His Ser Pro Gln Gln Leu Ala Glu Glu Ala Thr Arg Lys Arg Glu Leu 
        115                 120                 125


Arg Leu Met Lys Asn Arg Glu Ala Ala Lys Glu Cys Arg Arg Arg Lys 
    130                 135                 140


Lys Glu Tyr Val Lys Cys Leu Glu Ser Arg Val Ala Val Leu Glu Val 
145                 150                 155                 160


Gln Asn Lys Lys Leu Ile Glu Glu Leu Glu Thr Leu Lys Asp Ile Cys 
                165                 170                 175


Ser Pro Lys Thr Asp Tyr 
            180


<210>  6556
<211>  616
<212>  DNA
<213>  Homo sapiens

<400>  6556
attcttagcc accgaagtat gggcaccaaa agcgataagg agcatgtgtt ccttaataaa     60

tgtcacatca gaaaatgact gttccaggac agtaaccacc tcccgatggt agcagcaatt    120

gcagagacag atgaatctgc agaatcagaa ggtgtaattg attctcataa acgtagagaa    180

atcctttcac gaagaccctc ttataggaaa atactgaatg aactgtcctc tgatgtgcct    240

ggtgttccca agattgaaga agagagatca gaggaagaag gaacaccacc tagtattgct    300

accatggcag taccaactag catatatcag actagcacgg ggcaatacat tgctatagcc    360

caaggtggaa caatccagat ttctaaccca ggatctgatg gtgttcaggg actgcaggca    420

ttaacaatga caaattcagg agctcctcca ccaggtgcta caattgtaca gtacgcagca    480

caatcagctg atggcacaca gcagttcttt gtcccaggga gtggtgatgg ctgcatcgcc    540

cggaagtttg cacagtcccc agcagctggc agaagaagca acacgcaaac gagagctgag    600

gctaatgaaa aacagg                                                    616


<210>  6557
<211>  169
<212>  PRT
<213>  Homo sapiens

<400>  6557

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ile Ala Ile Ala Gln Gly Gly Thr Ile Gln Ile Ser Asn Pro Gly 
                85                  90                  95


Ser Asp Gly Val Gln Gly Leu Gln Ala Leu Thr Met Thr Asn Ser Gly 
            100                 105                 110


Ala Pro Pro Pro Gly Ala Thr Ile Val Gln Tyr Ala Ala Gln Ser Ala 
        115                 120                 125


Asp Gly Thr Gln Gln Phe Phe Val Pro Gly Ser Gly Asp Gly Cys Ile 
    130                 135                 140


Ala Arg Lys Phe Ala Gln Ser Pro Ala Ala Gly Arg Arg Ser Asn Thr 
145                 150                 155                 160


Gln Thr Arg Ala Glu Ala Asn Glu Lys 
                165


<210>  6558
<211>  910
<212>  DNA
<213>  Homo sapiens

<400>  6558
accgaagtat gggcaccaaa agcgataagg agcatgtgtt ccttaataaa tgtcacatca     60

gaaaatgact gttccaggac agtaaccacc tcccgatggt agcagcaatt gcagagacag    120

atgaatctgc agaatcagaa ggtgtaattg attctcataa acgtagagaa atcctttcac    180

gaagaccctc ttataggaaa atactgaatg aactgtcctc tgatgtgcct ggtgttccca    240

agattgaaga agagagatca gaggaagaag gaacaccacc tagtattgct accatggcag    300

taccaactag catatatcag actagcacgg ggcaatacag tatgtatgct gcaattcgat    360

atgatacagt gctagcttta agtcttctct agttatattg aagcaactca ggttttggca    420

ttaaattgtt ccattttaaa atgcatcatt aatacctaaa ctgtatcata gaatgaaagt    480

atatgttaaa aagtgagatc tttgtattga cagctgtcat ataattttga aaagtaaaaa    540

ttttgactgc cgaatataga agaaaatttt ggggtaaaaa ggagaatttt tcctatttac    600

atgtttatat taatctctag taaaacattg tttttgttgt ctttatgatg catgcgaaca    660

taaatgtctg tatttcattc ttgttggctt ttgttaccca caattacata ctattcttac    720

taatctgaga gttttctaaa gtatgttttc aatgtttcac tactctctac tctgttaatt    780

tgtgctacag tttttcctaa aagagaatgg aaaaatgatt taatttttta aactgtagca    840

attggataga taattttatt tgaaatttta cacactgaaa gctctaaata aacagataca    900

ttcacattca                                                           910


<210>  6559
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  6559

Met Val Ala Ala Ile Ala Glu Thr Asp Glu Ser Ala Glu Ser Glu Gly 
1               5                   10                  15


Val Ile Asp Ser His Lys Arg Arg Glu Ile Leu Ser Arg Arg Pro Ser 
            20                  25                  30


Tyr Arg Lys Ile Leu Asn Glu Leu Ser Ser Asp Val Pro Gly Val Pro 
        35                  40                  45


Lys Ile Glu Glu Glu Arg Ser Glu Glu Glu Gly Thr Pro Pro Ser Ile 
    50                  55                  60


Ala Thr Met Ala Val Pro Thr Ser Ile Tyr Gln Thr Ser Thr Gly Gln 
65                  70                  75                  80


Tyr Ser Met Tyr Ala Ala Ile Arg Tyr Asp Thr Val Leu Ala Leu Ser 
                85                  90                  95


Leu Leu 



<210>  6560
<211>  4588
<212>  DNA
<213>  Homo sapiens

<400>  6560
atggtaggta tagggctgtg gatatcgtca gtttgaccaa gtattccaag aggccccatg     60

gagtttgtca tctgtaatag aggacgttag tgcattagtg atgaaaaaac tgcttaccac    120

tgactattgt gatctcccag ggagtataag gcagctccgc acttgaaatc catggcccaa    180

aatgactcta ccagtggaga ctctcttctg tgaagaagac gaccagataa gaggttggga    240

tgagcatgcc actgcatcag atctctgcca ttccatccca ggatgccatc tctgctagag    300

tctacagaag taagaccaaa gaaaaggaga gggaagaaca gaatgagaag actttgggac    360

atttcatgag tcattcaagc aacatttcta aggctgggag tcctccgtca gcatcagctc    420

cggctccggt gtcctccttc tctcgcactt ctatcacgcc atccagccag gacatctgca    480

gtgggagaag ttgcagatga cgtccagcga gcgcaggaag atcatgtgct cagtgacatt    540

ccacgtcatt gccatcacat gtgtggtctg gtccttgtat gtgctcattg accgtactgc    600

tgaggagatc aagcaggggc aggcaacagg aatcctagaa tggccctttt ggactaaatt    660

ggtggttgtg gccatcggct tcaccggagg acttcttttt atgtatgttc agtgtaaagt    720

gtatgtgcaa ttgtggaaga gactcaaggc ctataataga gtgatctatg ttcaaaactg    780

tccagaaaca agcaaaaaga atatttttga aaaatctcca ctaacagagc ccaactttga    840

aaataaacat ggatatggaa tctgtcattc cgacacaaac tcttcttgtt gcacagagcc    900

tgaagacact ggagcagaaa tcattcacgt ctgattgtgt gcgggttgtc attttcctgg    960

acatccatga agagctgaag gaaattgttt actgccaatt gtataccttt cttatgtcct   1020

ttaatagcat agactggaca ggtgactatt tatagtggct tctctttttc taaaccctcc   1080

ttagtctcct agaaaacctt cctgtgggcc aggcatgcct gggtcctgcc tctgcctggc   1140

agctctgtgg gaaagtggaa gaccccatga tgacatcatg gggagccagc agagttcctg   1200

cccatggtct tgagctgaat gagagaataa aatgccaatc ccaagggaag aggaggagca   1260

ggggtgccca ggccctgata cccagccgcc tccagcttgc agtggtcccc agcctggagc   1320

agagcattgg ggagtgtcta gccatgacga gaagattccc tctgcatcac ggcgaacccc   1380

aggagatggt attgaaacag acccccaaac acagactcct gcctgccctc tgccgatgct   1440

gcctcctcca tgctcttgag caggtggagc catggtgctc tgtggtggcg catgattcac   1500

tgagcaaaca gcactttaca gaagaaaatc tttattttgt aatatgtgtg tccagcggga   1560

ttgacactca aaaaaagtct cacttagaaa tcttcccttc cttacctttg tatctccttt   1620

acatcatgag agatcaaaaa tccattttgc cttacatatg ctaagaagcg tggcattctt   1680

tctgttcata aaacagactc atgactttta agacaggaca agcaggccag aggctttttt   1740

tttaatcaca gatctcatgg gaattagtgg atgctaaatg gcaattaaag catgattcct   1800

atgcttttga gcctgtttta tgacaaggtg ttactttgta gacctggccc atacatttct   1860

tttttgtcaa cactgaaaaa gaacagtttc tgagatcgaa atggaaggaa aggaagtgag   1920

taatgacaac aaaactgaat atttaaaaaa tattccttta tagttaaatc tctccagttg   1980

gtgttggctt cacattgaaa gagcagccat gtgccaccct ggccggggtg tgtgcactgc   2040

atgcaggttc tcccttgcat gcaagatggg tgctggccca ctgtgaggct tctgctcggg   2100

gaagttctgt ggagtcacta ccagggccaa gaggcaggtg ggctggctct gggacgaggg   2160

ccaggtgtga gcaaactgcc agggtccgct gtgccactgc tccccggcca catgcccgcc   2220

cagctgtcgc cttaaccaga ctgaacagac aggatccttc agggcccttg gccccactct   2280

cagtgcattc tgtcatcagg gattaccacc tgtaccattt tcataaaaca aaaccaaaat   2340

cactaccatc aaatggcctt gtccctctaa aaagtctgct taaaattctg tttttaaaac   2400

ccagtttcct agttttccag gcaaatagtt acctccggga aagttgctgg gggggcctga   2460

agcacaatgt agcgcagatg cttcctttcc aggccattct ctcacccagc ctgcacggag   2520

gagatgggag atgctggggg tcctgccctc agtctttttg ggccttaggc gtttcgttca   2580

tcctgctaag gggatgaagc aaacacgagg tgattccttt gcctttcaga gtggaagccc   2640

tggagtttgt tttgaaggcc aggaggctga aggatctcta agctacggtg tgggcttaat   2700

agcagcaggc tttgtcctcc tgtctcctcc aagccagtgt ctgattcctt ggcaacacag   2760

gtcttagtct gtggagtggc tctgctgtgg ccttcctctg gccgggcagg cactgtccag   2820

ccatagccag ctcctgagaa taggtcagcc tctcctttct gtctcccagg gcacatccag   2880

cccgtgcctg tgttcactgt gccccgaagt gcaattaccc ataccccttc tcagcctggg   2940

gaccccaggc aaccacagac tgtccactca ggggagctga atcccaggtc agccctgcca   3000

atgtccctta ggaactgccc aggcaaggcc cctggttttg tatacttgtt cctgccaccc   3060

agcagtagat gagtgtttca ggtgaagacc aggatagatt ttctaagtgt gaatccccac   3120

ttcacatatg gaacccctta tgctgaactt gaaaagcacc aagacttcct gtagacaaga   3180

aagtgcttag gtagggacag cccctgggca tcccacccaa tgtagctggc accccactat   3240

ggcaaaggtg ccttgataac tgagccctgt atccctccca tgcccagcca gattctcatg   3300

ggaagccctc tcccttcttt tctgcctaac accatctcat cgtttctggc ctcactgtgg   3360

acaatccaca cacattcttc tttcctctcc tggcggggca cagagccacc cccttgcctt   3420

ttcttttctt gaaggttcta gttcagctcc tgattcatca gacccttcta gccccctgca   3480

tctagcagtg aagcatgaag cctggtgggg atgtggtact cccatctggt gtggccacca   3540

gctctgccaa tgttcctgta gccttggaaa acttgctctc tcggttcttt tgggtgctgt   3600

gtactcccca gcttcccccc ttcccccccc attttgcacc tgggtttagt gaaaggatgg   3660

catttggttg acccatatag aaacccagaa tgaggtctca gggccaggag gcctggtatt   3720

tgtaggccag ggaaggggaa gaggcaagtg gtctggggta tcaccagcca gccctctctg   3780

atttggcctc tactccccat aagtcacagt accataagca ggcttctggc ctcagcaatt   3840

tggtctttgt gcccaagttt attgtgagaa tttcctgaaa actctataaa aggtctcttc   3900

ctactgtagg cctctaatgt ttctcccctt tttgcttcag tccactcttc agtcttgtag   3960

gcctagtttt caaacctgca catgtgtcct acctggccac aggcatgcag gcctcaggca   4020

gctgggccag tttgggagcc tcgggtgatg tctgcacgat ctggggctgc ctctgcaccc   4080

ctgctgtggg cttcagggtt ggagaagggc tgggaccaac cgggtgagat ccacaagtct   4140

ctggatgtgg ctgaaggcaa atacacaatt gaagtacttt ctgttttgaa gtgctttccc   4200

ttttgaatct ggtttgaaac atgcagcttc tgtctctagc ccaaggaaag accaaaacat   4260

agggaaataa aagcatttat ctttgtcttg gaagtaattg ttgaagttgt gcagttgatc   4320

agtgcacagt tagatgcaat gtttatagaa attgattgtt aaaccaaatt tacactggca   4380

tgtgtggtgt agtttctaaa aggcacttca catttgaaat ttttcttacc ttagaaagtt   4440

tctagtgatc taaatgtcta gttttgtatt cttttgtgtg tgttcactgt ttctcagtat   4500

taccacttga ataattctct gtacaggggg gtttgtgcta tacactggga tgtctaattg   4560

cagcaataaa gcctttcttt aaaaagga                                      4588


<210>  6561
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  6561

Met Thr Ser Ser Glu Arg Arg Lys Ile Met Cys Ser Val Thr Phe His 
1               5                   10                  15


Val Ile Ala Ile Thr Cys Val Val Trp Ser Leu Tyr Val Leu Ile Asp 
            20                  25                  30


Arg Thr Ala Glu Glu Ile Lys Gln Gly Gln Ala Thr Gly Ile Leu Glu 
        35                  40                  45


Trp Pro Phe Trp Thr Lys Leu Val Val Val Ala Ile Gly Phe Thr Gly 
    50                  55                  60


Gly Leu Leu Phe Met Tyr Val Gln Cys Lys Val Tyr Val Gln Leu Trp 
65                  70                  75                  80


Lys Arg Leu Lys Ala Tyr Asn Arg Val Ile Tyr Val Gln Asn Cys Pro 
                85                  90                  95


Glu Thr Ser Lys Lys Asn Ile Phe Glu Lys Ser Pro Leu Thr Glu Pro 
            100                 105                 110


Asn Phe Glu Asn Lys His Gly Tyr Gly Ile Cys His Ser Asp Thr Asn 
        115                 120                 125


Ser Ser Cys Cys Thr Glu Pro Glu Asp Thr Gly Ala Glu Ile Ile His 
    130                 135                 140


Val 
145


<210>  6562
<211>  1985
<212>  DNA
<213>  Homo sapiens

<400>  6562
atggtaggta tagggctgtg gatatcgtca gtttgaccaa gtattccaag aggccccatg     60

gagtttgtca tctgtaatag aggacgttag tgcattagtg atgaaaaaac tgcttaccac    120

tgactattgt gatctcccag ggagtataag gcagctccgc acttgaaatc catggcccaa    180

aatgactcta ccagtggaga ctctcttctg tgaagaagac gaccagataa gaggttggga    240

tgagcatgcc actgcatcag atctctgcca ttccatccca ggatgccatc tctgctagag    300

tctacagaag taagaccaaa gaaaaggaga gggaagaaca gaatgagaag actttgggac    360

atttcatgag tcattcaagc aacatttcta aggctgggag tcctccgtca gcatcagctc    420

cggctccggt gtcctccttc tctcgcactt ctatcacgcc atccagccag gacatctgca    480

ggatctgcca ctgtgaagga gatgatgaga gccccctgat caccccctgc cactgcacag    540

gaagcctcca cttcgtgcac caggcctgcc tgcagcagtg gatcaagagc tccgacacgc    600

gctgctgcga gctctgcaag tatgagttca tcatggagac caagctgaag ccactgagaa    660

aatgggagaa gttgcagatg acgtccagcg agcgcaggaa gatcatgtgc tcagtgacat    720

tccacgtcat tgccatcaca tgtgtggtct ggtccttgta tgtgctcatt gaccgtactg    780

ctgaggagat caagcagggg caggcaacag gaatcctaga atggcccttt tggactaaat    840

tggtggttgt ggccatcggc ttcaccggag gacttctttt tatgtatgtt cagtgtaaag    900

tgtatgtgca attgtggaag agactcaagg cctataatag agtgatctat gttcaaaact    960

gtccagaaac aagcaaaaag aatatttttg aaaaatctcc actaacagag cccaactttg   1020

aaaataaaca tggatatgga atctgtcatt ccgacacaaa ctcttcttgt tgcacagagc   1080

ctgaagacac tggagcagaa atcattcacg tctgattgtg tgcgggttgt cattttcctg   1140

gacatccatg aagagctgaa ggaaattgtt tactgccaat tgtatacctt tcttatgtcc   1200

tttaatagca tagactggac aggtgactat ttatagtggc ttctcttttt ctaaaccctc   1260

cttagtctcc tagaaaacct tcctgtgggc caggcatgcc tgggtcctgc ctctgcctgg   1320

cagctctgtg ggaaagtgga agaccccatg atgacatcat ggggagccag cagagttcct   1380

gcccatggtc ttgagctgaa tgagagaata aaatgccaat cccaagggaa gaggaggagc   1440

aggggtgccc aggccctgat acccagccgc ctccagcttg cagtggtccc cagcctggag   1500

cagagcattg gggagtgtct agccatgacg agaagattcc ctctgcatca cggcgaaccc   1560

caggagatgg tattgaaaca gacccccaaa cacagactcc tgcctgccct ctgccgatgc   1620

tgcctcctcc atgctcttga gcaggtggag ccatggtgct ctgtggtggc gcatgattca   1680

ctgagcaaac agcactttac agaagaaaat ctttattttg taatatgtgt gtccagcggg   1740

attgacactc aaaaaaagtc tcacttagaa atcttccctt ccttaccttt gtatctcctt   1800

tacatcatga gagatcaaaa atccattttg ccttacatat gctaagaagc gtggcattct   1860

ttctgttcat aaaacagact catgactttt aagacaggac aagcaggcca gaggcttttt   1920

ttttaatcac agatctcatg ggaattagtg gatgctaaat ggcaattaaa gcatgattcc   1980

tatgc                                                               1985


<210>  6563
<211>  291
<212>  PRT
<213>  Homo sapiens

<400>  6563

Met Ser Met Pro Leu His Gln Ile Ser Ala Ile Pro Ser Gln Asp Ala 
1               5                   10                  15


Ile Ser Ala Arg Val Tyr Arg Ser Lys Thr Lys Glu Lys Glu Arg Glu 
            20                  25                  30


Glu Gln Asn Glu Lys Thr Leu Gly His Phe Met Ser His Ser Ser Asn 
        35                  40                  45


Ile Ser Lys Ala Gly Ser Pro Pro Ser Ala Ser Ala Pro Ala Pro Val 
    50                  55                  60


Ser Ser Phe Ser Arg Thr Ser Ile Thr Pro Ser Ser Gln Asp Ile Cys 
65                  70                  75                  80


Arg Ile Cys His Cys Glu Gly Asp Asp Glu Ser Pro Leu Ile Thr Pro 
                85                  90                  95


Cys His Cys Thr Gly Ser Leu His Phe Val His Gln Ala Cys Leu Gln 
            100                 105                 110


Gln Trp Ile Lys Ser Ser Asp Thr Arg Cys Cys Glu Leu Cys Lys Tyr 
        115                 120                 125


Glu Phe Ile Met Glu Thr Lys Leu Lys Pro Leu Arg Lys Trp Glu Lys 
    130                 135                 140


Leu Gln Met Thr Ser Ser Glu Arg Arg Lys Ile Met Cys Ser Val Thr 
145                 150                 155                 160


Phe His Val Ile Ala Ile Thr Cys Val Val Trp Ser Leu Tyr Val Leu 
                165                 170                 175


Ile Asp Arg Thr Ala Glu Glu Ile Lys Gln Gly Gln Ala Thr Gly Ile 
            180                 185                 190


Leu Glu Trp Pro Phe Trp Thr Lys Leu Val Val Val Ala Ile Gly Phe 
        195                 200                 205


Thr Gly Gly Leu Leu Phe Met Tyr Val Gln Cys Lys Val Tyr Val Gln 
    210                 215                 220


Leu Trp Lys Arg Leu Lys Ala Tyr Asn Arg Val Ile Tyr Val Gln Asn 
225                 230                 235                 240


Cys Pro Glu Thr Ser Lys Lys Asn Ile Phe Glu Lys Ser Pro Leu Thr 
                245                 250                 255


Glu Pro Asn Phe Glu Asn Lys His Gly Tyr Gly Ile Cys His Ser Asp 
            260                 265                 270


Thr Asn Ser Ser Cys Cys Thr Glu Pro Glu Asp Thr Gly Ala Glu Ile 
        275                 280                 285


Ile His Val 
    290


<210>  6564
<211>  1842
<212>  DNA
<213>  Homo sapiens

<400>  6564
atggtaggta tagggctgtg gatatcgtca gtttgaccaa gtattccaag aggccccatg     60

gagtttgtca tctgtaatag aggacgttag tgcattagtg atgaaaaaac tgcttaccac    120

tgactattgt gatctcccag ggagtataag gcagctccgc acttgaaatc catggcccaa    180

aatgactcta ccagtggaga ctctcttctg tgaagaagac gaccagataa gaggttggga    240

tgagcatgcc actgcatcag atctctgcca ttccatccca ggatgccatc tctgctagag    300

tctacagaag taagaccaaa gaaaaggaga gggaagaaca gaatgagaag actttgggac    360

atttcatgag tcattcaagc aacatttcta aggctgggag tcctccgtca gcatcagctc    420

cggctccggt gtcctccttc tctcgcactt ctatcacgcc atccagccag gacatctgca    480

ggatctgcca ctgtgaagga gatgatgaga gccccctgat caccccctgc cactgcacag    540

gaagcctcca cttcgtgcac caggcctgcc tgcagcagtg gatcaagagc tccgacacgc    600

gctgctgcga gctctgcaag tatgagttca tcatggagac caagctgaag ccactgagaa    660

aatgggagaa gttgcagatg acgtccagcg agcgcaggaa gatcatgtgc tcagtgacat    720

tccacgtcat tgccatcaca tgtgtggtct ggtccttgta tgtgctcatt gaccgtactg    780

ctgaggagat caagcagggg caggcaacag gaatcctaga atggcccttt tggactaaat    840

tggtggttgt ggccatcggc ttcaccggag gacttctttt tatgtatgtt cagtgtaaag    900

tgtatgtgca attgtggaag agactcaagg cctataatag agtgatctat gttcaaaact    960

gtccagaaac aagcaaaaag aatatttttg aaaaatctcc actaacagag cccaactttg   1020

aaaataaaca tggatatgga atctgtcatt ccgacacaaa ctcttcttgt tgcacagagc   1080

ctgaagacac tggagcagaa atcattcacg tctgattgtg tgcgggttgt cattttcctg   1140

gacatccatg aagagctgaa ggaaattgtt tactgccaat tgtatacctt tcttatgtcc   1200

tttaatagca tagactggac aggtgactat ttatagtggc ttctcttttt ctaaaccctc   1260

cttagtctcc tagaaaacct tcctgtgggc caggcatgcc tgggtcctgc ctctgcctgg   1320

cagctctgtg ggaaagtgga agaccccatg atgacatcat ggggagccag cagagttcct   1380

gcccatggtc ttgagctgaa tgagagaata aaatgccaat cccaagggaa gaggaggagc   1440

aggggtgccc aggccctgat acccagccgc ctccagcttg cagtggtccc cagcctggag   1500

cagagcattg gggagtgtct agccatgacg agaagattcc ctctgcatca cggcgaaccc   1560

caggagatgg tattgaaaca gacccccaaa cacagactcc tgcctgccct ctgccgatgc   1620

tgcctcctcc atgctcttga gcaggtggag ccatggtgct ctgtggtggc gcatgattca   1680

ctgagcaaac agcactttac agaagaaaat ctttattttg taatatgtgt gtccagcggg   1740

attgacactc aaaaaaagtc tcacttagaa atcttccctt ccttaccttt gtatctcctt   1800

tacatcatga gagatcaaaa atccattttg ccttacatat gc                      1842


<210>  6565
<211>  291
<212>  PRT
<213>  Homo sapiens

<400>  6565

Met Ser Met Pro Leu His Gln Ile Ser Ala Ile Pro Ser Gln Asp Ala 
1               5                   10                  15


Ile Ser Ala Arg Val Tyr Arg Ser Lys Thr Lys Glu Lys Glu Arg Glu 
            20                  25                  30


Glu Gln Asn Glu Lys Thr Leu Gly His Phe Met Ser His Ser Ser Asn 
        35                  40                  45


Ile Ser Lys Ala Gly Ser Pro Pro Ser Ala Ser Ala Pro Ala Pro Val 
    50                  55                  60


Ser Ser Phe Ser Arg Thr Ser Ile Thr Pro Ser Ser Gln Asp Ile Cys 
65                  70                  75                  80


Arg Ile Cys His Cys Glu Gly Asp Asp Glu Ser Pro Leu Ile Thr Pro 
                85                  90                  95


Cys His Cys Thr Gly Ser Leu His Phe Val His Gln Ala Cys Leu Gln 
            100                 105                 110


Gln Trp Ile Lys Ser Ser Asp Thr Arg Cys Cys Glu Leu Cys Lys Tyr 
        115                 120                 125


Glu Phe Ile Met Glu Thr Lys Leu Lys Pro Leu Arg Lys Trp Glu Lys 
    130                 135                 140


Leu Gln Met Thr Ser Ser Glu Arg Arg Lys Ile Met Cys Ser Val Thr 
145                 150                 155                 160


Phe His Val Ile Ala Ile Thr Cys Val Val Trp Ser Leu Tyr Val Leu 
                165                 170                 175


Ile Asp Arg Thr Ala Glu Glu Ile Lys Gln Gly Gln Ala Thr Gly Ile 
            180                 185                 190


Leu Glu Trp Pro Phe Trp Thr Lys Leu Val Val Val Ala Ile Gly Phe 
        195                 200                 205


Thr Gly Gly Leu Leu Phe Met Tyr Val Gln Cys Lys Val Tyr Val Gln 
    210                 215                 220


Leu Trp Lys Arg Leu Lys Ala Tyr Asn Arg Val Ile Tyr Val Gln Asn 
225                 230                 235                 240


Cys Pro Glu Thr Ser Lys Lys Asn Ile Phe Glu Lys Ser Pro Leu Thr 
                245                 250                 255


Glu Pro Asn Phe Glu Asn Lys His Gly Tyr Gly Ile Cys His Ser Asp 
            260                 265                 270


Thr Asn Ser Ser Cys Cys Thr Glu Pro Glu Asp Thr Gly Ala Glu Ile 
        275                 280                 285


Ile His Val 
    290


<210>  6566
<211>  767
<212>  DNA
<213>  Homo sapiens

<400>  6566
aagcaccaca ggtagctttt ggcatggtag gtatagggct gtggatatcg tcagtttgac     60

caagtattcc aagaggcccc atggagtttg tcatctgtaa tagaggacgt tagtgcatta    120

gtgatgaaaa aactgcttac cactgactat tgtgatctcc cagggagtat aaggcagctc    180

cgcacttgaa atccatggcc caaaatgact ctaccagtgg agactctctt ctgtgaagaa    240

gacgaccaga taagaggttg ggatgagcat gccactgcat cagatctctg ccattccatc    300

ccaggatgcc atctctgcta gagtctacag aagtaagacc aaagaaaagg agagggaaga    360

acagaatgag aagactttgg gacatttcat gagtcattca agcaacattt ctaaggctgg    420

gagtcctccg tcagcatcag ctccggctcc ggtgtcctcc ttctctcgca cttctatcac    480

gccatccagc caggacatct gcagttccag tgcagtgttt tctgagtgtt gtcaccacag    540

ttccgtgcag tctgctgttg tctcgaaagc tcctcactgc cagagttctc tgacacaagg    600

gctcactgtg acagttatct gtaaggacac attacaggcg tcaaagagaa attcctttgg    660

ttcagaatgg gcccaggcct tgaagcctgc taagaatacc aaagccagaa gaacactaaa    720

gttctcaagg tccctcaatg atgtgggtga gaaggcgcag gatactt                  767


<210>  6567
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  6567

Met Ser Met Pro Leu His Gln Ile Ser Ala Ile Pro Ser Gln Asp Ala 
1               5                   10                  15


Ile Ser Ala Arg Val Tyr Arg Ser Lys Thr Lys Glu Lys Glu Arg Glu 
            20                  25                  30


Glu Gln Asn Glu Lys Thr Leu Gly His Phe Met Ser His Ser Ser Asn 
        35                  40                  45


Ile Ser Lys Ala Gly Ser Pro Pro Ser Ala Ser Ala Pro Ala Pro Val 
    50                  55                  60


Ser Ser Phe Ser Arg Thr Ser Ile Thr Pro Ser Ser Gln Asp Ile Cys 
65                  70                  75                  80


Ser Ser Ser Ala Val Phe Ser Glu Cys Cys His His Ser Ser Val Gln 
                85                  90                  95


Ser Ala Val Val Ser Lys Ala Pro His Cys Gln Ser Ser Leu Thr Gln 
            100                 105                 110


Gly Leu Thr Val Thr Val Ile Cys Lys Asp Thr Leu Gln Ala Ser Lys 
        115                 120                 125


Arg Asn Ser Phe Gly Ser Glu Trp Ala Gln Ala Leu Lys Pro Ala Lys 
    130                 135                 140


Asn Thr Lys Ala Arg Arg Thr Leu Lys Phe Ser Arg Ser Leu Asn Asp 
145                 150                 155                 160


Val Gly Glu Lys Ala Gln Asp 
                165


<210>  6568
<211>  555
<212>  DNA
<213>  Homo sapiens

<400>  6568
gatatcgtca gtttgaccaa gtattccaag aggccccatg gagtttgtca tctgtaatag     60

aggacgttag tgcattagtg atgaaaaaac tgcttaccac tgactattgt gatctcccag    120

ggagtataag gcagctccgc acttgaaatc catggcccaa aatgactcta ccagtggaga    180

ctctcttctg tgaagaagac gaccagataa gaggttggga tgagcatgcc actgcatcag    240

atctctgcca ttccatccca ggatgccatc tctgctagag tctacagaag taagaccaaa    300

gaaaaggaga gggaagaaca gaatgagaag actttgggac atttcatgag tcattcaagc    360

aacatttcta agtgtttctg attacactac cttgagctgt cacatctaag gtgacctggg    420

cctggccact tggaacctga tcctgtgcaa tatccccttg gtcatgatga tctaggctca    480

acaccacatg gaagctgcca aggcttgggg cttgcaccct ctgaagccat gacctgaact    540

ataccctggc tgctt                                                     555


<210>  6569
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  6569

Met Ser Met Pro Leu His Gln Ile Ser Ala Ile Pro Ser Gln Asp Ala 
1               5                   10                  15


Ile Ser Ala Arg Val Tyr Arg Ser Lys Thr Lys Glu Lys Glu Arg Glu 
            20                  25                  30


Glu Gln Asn Glu Lys Thr Leu Gly His Phe Met Ser His Ser Ser Asn 
        35                  40                  45


Ile Ser Lys Cys Phe 
    50


<210>  6570
<211>  1230
<212>  DNA
<213>  Homo sapiens

<400>  6570
atgggagaaa taaaactggc agtggttgaa actatttctg ggaagtttga tgtaggaaaa     60

ttggatttgg tagacagtga tgaaagtgac agaggaataa tgagagtttt atgtggacaa    120

aagatgaatg cagagtctgg cccgtcaggg ccaggagaca ctaaacgaca cacacagagc    180

tggggaagtc ttttcggttc caagcccagt gggttgtcgc ctgggcactg cgaaggggtg    240

gaagcacaga aaggccgcgc ggcggcaccc gctgcagccc gcccccagcg cgctgcagtc    300

gccggggcaa cgcctccacc caactcggcc ggacacgtga cgcccgcgtc acgtgacctg    360

ccactcggtg tcctcccgcg gaggggcgta gggtgtaaac aggcgacgcg ctgggggagg    420

tgcggccttg ctgcgtccac gtctcgggca tgctcgaggc gggccagggc ggtagcgccg    480

ccagctcaga gcccacctga ggtaactcct gcggcctcta ggatcggagt cccccacgcc    540

gcgcgcagcc gccgccgctg gccgccaata agggcggccg agcccccggc ccgggcaggg    600

ggtgtggctg ccggcagcgc gtcggctaca ggtgggctgg gctgggctgg gctgggctgg    660

gctgggtggg ggcggccgcc aaggacccat ccctgcgctg cgggcccggc gtggagcccg    720

cggagaggca gcgcgactcc aggcagtggg tctctctgcc ccggtgctcg cgtctgcccc    780

tggggccggg ccgagcggaa ccaggaatcg cagaaacggt cagcgcccag ggctctaggc    840

cggccgcccc gggtgccagg tgaattcctt tccctgaccg gctgtgagac gttggcccgt    900

cagccgtcgt ctttggcctg agtgtgcaca tctgtaaaat ggaagctcgg actagtgatc    960

cgtgaggacc ttccacgtct gacgtgtgat ctcgagagac ctgcgtacat tcggggtgcc   1020

agaaggaaag catagttgct ccgatacaga atgggaatgg gagacttttg aggccaaccg   1080

aatgggttag gacatatctg aaaaacatga aaacgctaaa aagcatgaaa actgaaggag   1140

tatacgaact caagtcgttg agagtcatga aataatgtga acatgctctt gtgtgaaatc   1200

ttgagaccct ggagcaagag aattttggat                                    1230


<210>  6571
<211>  306
<212>  PRT
<213>  Homo sapiens

<400>  6571

Met Gly Glu Ile Lys Leu Ala Val Val Glu Thr Ile Ser Gly Lys Phe 
1               5                   10                  15


Asp Val Gly Lys Leu Asp Leu Val Asp Ser Asp Glu Ser Asp Arg Gly 
            20                  25                  30


Ile Met Arg Val Leu Cys Gly Gln Lys Met Asn Ala Glu Ser Gly Pro 
        35                  40                  45


Ser Gly Pro Gly Asp Thr Lys Arg His Thr Gln Ser Trp Gly Ser Leu 
    50                  55                  60


Phe Gly Ser Lys Pro Ser Gly Leu Ser Pro Gly His Cys Glu Gly Val 
65                  70                  75                  80


Glu Ala Gln Lys Gly Arg Ala Ala Ala Pro Ala Ala Ala Arg Pro Gln 
                85                  90                  95


Arg Ala Ala Val Ala Gly Ala Thr Pro Pro Pro Asn Ser Ala Gly His 
            100                 105                 110


Val Thr Pro Ala Ser Arg Asp Leu Pro Leu Gly Val Leu Pro Arg Arg 
        115                 120                 125


Gly Val Gly Cys Lys Gln Ala Thr Arg Trp Gly Arg Cys Gly Leu Ala 
    130                 135                 140


Ala Ser Thr Ser Arg Ala Cys Ser Arg Arg Ala Arg Ala Val Ala Pro 
145                 150                 155                 160


Pro Ala Gln Ser Pro Pro Glu Val Thr Pro Ala Ala Ser Arg Ile Gly 
                165                 170                 175


Val Pro His Ala Ala Arg Ser Arg Arg Arg Trp Pro Pro Ile Arg Ala 
            180                 185                 190


Ala Glu Pro Pro Ala Arg Ala Gly Gly Val Ala Ala Gly Ser Ala Ser 
        195                 200                 205


Ala Thr Gly Gly Leu Gly Trp Ala Gly Leu Gly Trp Ala Gly Trp Gly 
    210                 215                 220


Arg Pro Pro Arg Thr His Pro Cys Ala Ala Gly Pro Ala Trp Ser Pro 
225                 230                 235                 240


Arg Arg Gly Ser Ala Thr Pro Gly Ser Gly Ser Leu Cys Pro Gly Ala 
                245                 250                 255


Arg Val Cys Pro Trp Gly Arg Ala Glu Arg Asn Gln Glu Ser Gln Lys 
            260                 265                 270


Arg Ser Ala Pro Arg Ala Leu Gly Arg Pro Pro Arg Val Pro Gly Glu 
        275                 280                 285


Phe Leu Ser Leu Thr Gly Cys Glu Thr Leu Ala Arg Gln Pro Ser Ser 
    290                 295                 300


Leu Ala 
305


<210>  6572
<211>  2798
<212>  DNA
<213>  Homo sapiens

<400>  6572
atctcttgat gtaatatgga aagtggagca ttaacttaca aaagttccta cagacgatcc     60

acttaggaag atggcagagt acttggattc cagtcgagtt gaggtctggg agaagacctc    120

ctgcagcaaa caagttacat ttttggtata ccaagaagga gatcaattga atttctttcc    180

tgcagtagat aggggagatg gcactttaac accgttatct gactcttcaa agaaaataga    240

ttttcatttg catgtcctac ggagaaaagg agaacatcgt atgagtggtg gttctatgta    300

taattcagat acagatgagg atgaagaaac tgagccttct tcttctgggc aacagataat    360

tgaaaattca ataactatga ataagatgaa gctgctgaag gctaagatga agaacatgaa    420

tctcagcaaa aagcctaaga aagctgtcaa gataaaacct cacccacctg tagctcctcg    480

accttctagt ggttccactg caccatctcg ccaccgattg ttaagggtcc tccccaacat    540

tggtcaatct tgttcacctg cttttgggaa tgcatatccg cccgaaatct ccaggaatgg    600

aatttcaagt ttggcaactc aactctctgc tgagagatac atatcttcta tcactggtga    660

atttcttaag gaagataata gctgggagaa taacacactg tctcacttca gtagcaacgt    720

caaactacct cctcagatac cccatttgga gttgggaaat gaccaggagc ttgctgactc    780

tgttctccat cttggatcat ccctgcctag gcaaacaaaa cattttttag gaaacttgcc    840

atctagtaat gggaacattg tcttaccttc agaagaatgt gtaaccgaac aatcacttct    900

acctaaagtg ggctcactgg cttcatttgc agaaggaaat gctgatgaac agagcagcgg    960

cttagaaggt gcgtgcaaag tgaatctgga gttgctactc actaatgctg acaaagggtt   1020

gaaagctcca gagcagcatc tcaagcatgt tgcaggagtg ctgaatgggg aatcagtaga   1080

gacttcagtt cttaactacc gggaattaag tcctcacaag aatagactct tgtcacctct   1140

tcgctgttct gcaccaatgt cgctacataa ttctctggtg aaaccagaga gacagtccaa   1200

atgttttgag tttgggaagc tacagccttc ttcttctcag tcactggatg ttcaaaacat   1260

aactgattct tctttctcta ggactacttg ctttcaaggt gttaaagttg attcacttgg   1320

gaaaagatct gatgttattt ccaaagttga ggctcgggat atcacagaaa tgactaacaa   1380

ggcttccaaa gagcctgttg gttgtgtaaa taatatcagt tttcttgcct cactggccgg   1440

gagcacaagc agaaatagat tacagagcac acgtggggca ggcaggcttc agaactctgg   1500

aactgggctg tctacaaacc tccagcattt tcaggaagaa aactttagga aaagttctcc   1560

ccagttagaa catacaggag tttttttgtc tacccatggt gttggaatga atggaaataa   1620

tgcagcagca gggaaaagcg taggagaatg tactactcat cacctcccac ctgtgaaagc   1680

ccctcttcag acaaagaaga aaacaacaaa tcattgtttt ctttgtggaa agaaaacagg   1740

actggctagt agctacgaat gcagatgtgg aaacaacttc tgtgcatctc atcgttatgc   1800

agaaactcat ggctgtacct atgattacaa gagtgcaggg aggagatact tgcacgaggc   1860

aaatcctgtg gttaatgcac caaagcttcc aaaaatctaa ctcttcctct acatcttact   1920

gttctgcccg ggattcgtat tataatgaca gaagaaatgt tgtttagact attatttttg   1980

ttcgactcta aaagatttgc caaataacaa aagcatacaa tgcatactgt tggagaacaa   2040

gaatgctact gtattttaca tctttatttc ttggtgaaac aaaagtttta aaagtagttt   2100

taacaacttt acactggaat gatttagctt tgttattgca tgtcttgtgt taagtgtttt   2160

gtatatgata ttgcagtttt actaggcaaa tcttcaaaag atgcacttta ggaaacgaaa   2220

tatttcctaa ataaccaggc ttccacattg tacagaatga gcagtcatgt aatgaatggc   2280

tctactcaga ttgaccatat gggttttttc tttttctttc ttttattctt ctccttcttt   2340

ttttttcaga ggtgggatgg gtggagattt tttaaaaatc ccacgtgtga aagtttactg   2400

gctttattag caagttcctt tttacttcaa gctacttttt ataaaaaaga acatttttcc   2460

agtgtggttt ttaacagata atacatttct tccacattca gattagtatt cggacatgaa   2520

tccattctat aaaacacatc gtgttcatga tagtgtatat tttactactt tttgaatgtt   2580

aattttaaaa tagaagatgt cccacttgcc attaaatata gaagccaact ttttaccttt   2640

tgaaatatgg ctacatttaa aacaaaatct cacagctcgg tttttcttat ttgttgagtg   2700

ctattaccag gagaaattca aataaatatt caatttcatt atgaatttca ttatttattt   2760

ataatagttt ttcttttata aataattttt cttttata                           2798


<210>  6573
<211>  609
<212>  PRT
<213>  Homo sapiens

<400>  6573

Met Ala Glu Tyr Leu Asp Ser Ser Arg Val Glu Val Trp Glu Lys Thr 
1               5                   10                  15


Ser Cys Ser Lys Gln Val Thr Phe Leu Val Tyr Gln Glu Gly Asp Gln 
            20                  25                  30


Leu Asn Phe Phe Pro Ala Val Asp Arg Gly Asp Gly Thr Leu Thr Pro 
        35                  40                  45


Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe His Leu His Val Leu Arg 
    50                  55                  60


Arg Lys Gly Glu His Arg Met Ser Gly Gly Ser Met Tyr Asn Ser Asp 
65                  70                  75                  80


Thr Asp Glu Asp Glu Glu Thr Glu Pro Ser Ser Ser Gly Gln Gln Ile 
                85                  90                  95


Ile Glu Asn Ser Ile Thr Met Asn Lys Met Lys Leu Leu Lys Ala Lys 
            100                 105                 110


Met Lys Asn Met Asn Leu Ser Lys Lys Pro Lys Lys Ala Val Lys Ile 
        115                 120                 125


Lys Pro His Pro Pro Val Ala Pro Arg Pro Ser Ser Gly Ser Thr Ala 
    130                 135                 140


Pro Ser Arg His Arg Leu Leu Arg Val Leu Pro Asn Ile Gly Gln Ser 
145                 150                 155                 160


Cys Ser Pro Ala Phe Gly Asn Ala Tyr Pro Pro Glu Ile Ser Arg Asn 
                165                 170                 175


Gly Ile Ser Ser Leu Ala Thr Gln Leu Ser Ala Glu Arg Tyr Ile Ser 
            180                 185                 190


Ser Ile Thr Gly Glu Phe Leu Lys Glu Asp Asn Ser Trp Glu Asn Asn 
        195                 200                 205


Thr Leu Ser His Phe Ser Ser Asn Val Lys Leu Pro Pro Gln Ile Pro 
    210                 215                 220


His Leu Glu Leu Gly Asn Asp Gln Glu Leu Ala Asp Ser Val Leu His 
225                 230                 235                 240


Leu Gly Ser Ser Leu Pro Arg Gln Thr Lys His Phe Leu Gly Asn Leu 
                245                 250                 255


Pro Ser Ser Asn Gly Asn Ile Val Leu Pro Ser Glu Glu Cys Val Thr 
            260                 265                 270


Glu Gln Ser Leu Leu Pro Lys Val Gly Ser Leu Ala Ser Phe Ala Glu 
        275                 280                 285


Gly Asn Ala Asp Glu Gln Ser Ser Gly Leu Glu Gly Ala Cys Lys Val 
    290                 295                 300


Asn Leu Glu Leu Leu Leu Thr Asn Ala Asp Lys Gly Leu Lys Ala Pro 
305                 310                 315                 320


Glu Gln His Leu Lys His Val Ala Gly Val Leu Asn Gly Glu Ser Val 
                325                 330                 335


Glu Thr Ser Val Leu Asn Tyr Arg Glu Leu Ser Pro His Lys Asn Arg 
            340                 345                 350


Leu Leu Ser Pro Leu Arg Cys Ser Ala Pro Met Ser Leu His Asn Ser 
        355                 360                 365


Leu Val Lys Pro Glu Arg Gln Ser Lys Cys Phe Glu Phe Gly Lys Leu 
    370                 375                 380


Gln Pro Ser Ser Ser Gln Ser Leu Asp Val Gln Asn Ile Thr Asp Ser 
385                 390                 395                 400


Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly Val Lys Val Asp Ser Leu 
                405                 410                 415


Gly Lys Arg Ser Asp Val Ile Ser Lys Val Glu Ala Arg Asp Ile Thr 
            420                 425                 430


Glu Met Thr Asn Lys Ala Ser Lys Glu Pro Val Gly Cys Val Asn Asn 
        435                 440                 445


Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser Thr Ser Arg Asn Arg Leu 
    450                 455                 460


Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln Asn Ser Gly Thr Gly Leu 
465                 470                 475                 480


Ser Thr Asn Leu Gln His Phe Gln Glu Glu Asn Phe Arg Lys Ser Ser 
                485                 490                 495


Pro Gln Leu Glu His Thr Gly Val Phe Leu Ser Thr His Gly Val Gly 
            500                 505                 510


Met Asn Gly Asn Asn Ala Ala Ala Gly Lys Ser Val Gly Glu Cys Thr 
        515                 520                 525


Thr His His Leu Pro Pro Val Lys Ala Pro Leu Gln Thr Lys Lys Lys 
    530                 535                 540


Thr Thr Asn His Cys Phe Leu Cys Gly Lys Lys Thr Gly Leu Ala Ser 
545                 550                 555                 560


Ser Tyr Glu Cys Arg Cys Gly Asn Asn Phe Cys Ala Ser His Arg Tyr 
                565                 570                 575


Ala Glu Thr His Gly Cys Thr Tyr Asp Tyr Lys Ser Ala Gly Arg Arg 
            580                 585                 590


Tyr Leu His Glu Ala Asn Pro Val Val Asn Ala Pro Lys Leu Pro Lys 
        595                 600                 605


Ile 



<210>  6574
<211>  2126
<212>  DNA
<213>  Homo sapiens

<400>  6574
gtgaagttgc tcgccgggtc gttgggccct gtcgacctgt aggcgggcga gcgagccaac     60

gccggccgct gctgcccggg gaccggagcg gcgggccgcc tttgcccagg acacacgctc    120

tggcgtttgt tcctttgggc gtgacgccag cttcaacggg tacgcggctt tcccgacggg    180

tgctgatctc cgagtcgctg ttgtcacgcg gactgctgtc ctccagattc aggccggtgg    240

gtctggggag cccggattgg tcttggagga gcaacggctg cgcaggtaca aaactcaaaa    300

catgaacaac aatatatatt accaatcttc aaacctggtt tgcctagaac tggaatacag    360

ttgcctgcga catattttag aagaactaga aaagtcaaag taatggataa cagaaaagag    420

cctccattct tcaatgatga taacatggga ccattttact acagacttca tttctgtgat    480

accatggagc tcttcattga aacattaact ggaacatgtt ttgagctgag agtttcacct    540

tttgaaactg ttatttctgt gaaagcaaaa attcgaagat tggaaggtat tcccatctgt    600

cgacaacact taatttggaa taacatggaa cttgaaaatg attattgctt gaatgattac    660

aacatttcag aagggtgtac cttgaagcta gttttggcta tgcgtggcgg acctataaat    720

actagaagag ttcctacaga cgatccactt aggaagatgg cagagtactt ggattccagt    780

cgagttgagg tctgggagaa gacctcctgc agcaaacaag ttacattttt ggtataccaa    840

gaaggagatc aattgaattt ctttcctgca gtagataggg gagatggcac tttaacaccg    900

ttatctgact cttcaaagaa aatagatttt catttgcatg tcctacggag aaaaggagaa    960

catcgtatga ggagaatgta ctactcatca cctcccacct gtgaaagccc ctcttcagac   1020

aaagaagaaa acaacaaatc attgttttct ttgtggaaag aaaacaggac tggctagtag   1080

ctacgaatgc agatgtggaa acaacttctg tgcatctcat cgttatgcag aaactcatgg   1140

ctgtacctat gattacaaga gtgcagggag gagatacttg cacgaggcaa atcctgtggt   1200

taatgcacca aagcttccaa aaatctaact cttcctctac atcttactgt tctgcccggg   1260

attcgtatta taatgacaga agaaatgttg tttagactat tatttttgtt cgactctaaa   1320

agatttgcca aataacaaaa gcatacaatg catactgttg gagaacaaga atgctactgt   1380

attttacatc tttatttctt ggtgaaacaa aagttttaaa agtagtttta acaactttac   1440

actggaatga tttagctttg ttattgcatg tcttgtgtta agtgttttgt atatgatatt   1500

gcagttttac taggcaaatc ttcaaaagat gcactttagg aaacgaaata tttcctaaat   1560

aaccaggctt ccacattgta cagaatgagc agtcatgtaa tgaatggctc tactcagatt   1620

gaccatatgg gttttttctt tttctttctt ttattcttct ccttcttttt ttttcagagg   1680

tgggatgggt ggagattttt taaaaatccc acgtgtgaaa gtttactggc tttattagca   1740

agttcctttt tacttcaagc tactttttat aaaaaagaac atttttccag tgtggttttt   1800

aacagataat acatttcttc cacattcaga ttagtattcg gacatgaatc cattctataa   1860

aacacatcgt gttcatgata gtgtatattt tactactttt tgaatgttaa ttttaaaata   1920

gaagatgtcc cacttgccat taaatataga agccaacttt ttaccttttg aaatatggct   1980

acatttaaaa caaaatctca cagctcggtt tttcttattt gttgagtgct attaccagga   2040

gaaattcaaa taaatattca atttcattat gaatttcatt atttatttat aatagttttt   2100

cttttataaa taatttttct tttata                                        2126


<210>  6575
<211>  224
<212>  PRT
<213>  Homo sapiens

<400>  6575

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Val Pro Thr 
            100                 105                 110


Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr Leu Asp Ser Ser Arg Val 
        115                 120                 125


Glu Val Trp Glu Lys Thr Ser Cys Ser Lys Gln Val Thr Phe Leu Val 
    130                 135                 140


Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe Pro Ala Val Asp Arg Gly 
145                 150                 155                 160


Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe 
                165                 170                 175


His Leu His Val Leu Arg Arg Lys Gly Glu His Arg Met Arg Arg Met 
            180                 185                 190


Tyr Tyr Ser Ser Pro Pro Thr Cys Glu Ser Pro Ser Ser Asp Lys Glu 
        195                 200                 205


Glu Asn Asn Lys Ser Leu Phe Ser Leu Trp Lys Glu Asn Arg Thr Gly 
    210                 215                 220


<210>  6576
<211>  2743
<212>  DNA
<213>  Homo sapiens

<400>  6576
atctcttgat gtaatatgga aagtggagca ttaacttaca aaagttccta cagacgatcc     60

acttaggaag atggcagagt acttggattc cagtcgagtt gaggtctggg agaagacctc    120

ctgcagcaaa caagttacat ttttggtata ccaagaagga gatcaattga atttctttcc    180

tgcagtagat aggggagatg gcactttaac accgttatct gactcttcaa agaaaataga    240

ttttcatttg catgtcctac ggagaaaagg agaacatcgt atgagtggtg gttctatgta    300

taattcagat acagatgagg atgaagaaac tgagccttct tcttctgggc aacagataat    360

tgaaaattca ataactatga ataagatgaa gctgctgaag gctaagatga agaacatgaa    420

tctcagcaaa aagcctaaga aagctgtcaa gataaaacct cacccacctg tagctcctcg    480

accttctagt ggttccactg caccatctcg ccaccgattg ttaagggtcc tccccaacat    540

tggtcaatct tgttcacctg cttttgggaa tgcatatccg cccgaaatct ccaggaatgg    600

aatttcaagt ttggcaactc aactctctgc tgagagatac atatcttcta tcactggtga    660

atttcttaag gaagataata gctgggagaa taacacactg tctcacttca gtagcaacgt    720

caaactacct cctcagatac cccatttgga gttgggaaat gaccaggagc ttgctgactc    780

tgttctccat cttggatcat ccctgcctag gcaaacaaaa cattttttag gaaacttgcc    840

atctagtaat gggaacattg tcttaccttc agaagaatgt gtaaccgaac aatcacttct    900

acctaaagtg ggctcactgg cttcatttgc agaaggaaat gctgatgaac agagcagcgg    960

cttagaaggt gcgtgcaaag tgaatctgga gttgctactc actaatgctg acaaagggtt   1020

gaaagctcca gagcagcatc tcaagcatgt tgcaggagtg ctgaatgggg aatcagtaga   1080

gacttcagtt cttaactacc gggaattaag tcctcacaag aatagactct tgtcacctct   1140

tcgctgttct gcaccaatgt cgctacataa ttctctggtg aaaccagaga gacagtccaa   1200

atgttttgag tttgggaagc tacagccttc ttcttctcag tcactggatg ttcaaaacat   1260

aactgattct tctttctcta ggactacttg ctttcaaggt gttaaagttg attcacttgg   1320

gaaaagatct gatgttattt ccaaagttga ggctcgggat atcacagaaa tgactaacaa   1380

ggcttccaaa gagcctgttg gttgtgtaaa taatatcagt tttcttgcct cactggccgg   1440

gagcacaagc agaaatagat tacagagcac acgtggggca ggcaggcttc agaactctgg   1500

aactgggctg tctacaaacc tccagcattt tcaggaagaa aactttagga aaagttctcc   1560

ccagttagaa catacaggag tttttttgtc tacccatggt gttggaatga atggaaataa   1620

tgcagcagca gggaaaagcg taggagaatg tactactcat cacctcccac ctgtgaaagc   1680

ccctcttcag acaaagaaga aaacaacaaa tcattgtttt ctttgtggaa agaaaacagg   1740

actggctagt agctacgaat gcagatgtgg aaacaacttc tgtgcatctc atcgttatgc   1800

agaaactcat ggctgtacct atgattacaa gagtgcaggg aggagatact tgcacgaggc   1860

aaatcctgtg gttaatgcac caaagcttcc aaaaatctaa ctcttcctct acatcttact   1920

gttctgcccg ggattcgtat tataatgaca gaagaaatgt tgtttagact attatttttg   1980

ttcgactcta aaagatttgc caaataacaa aagcatacaa tgcatactgt tggagaacaa   2040

gaatgctact gtattttaca tctttatttc ttggtgaaac aaaagtttta aaagtagttt   2100

taacaacttt acactggaat gatttagctt tgttattgca tgtcttgtgt taagtgtttt   2160

gtatatgata ttgcagtttt actaggcaaa tcttcaaaag atgcacttta ggaaacgaaa   2220

tatttcctaa ataaccaggc ttccacattg tacagaatga gcagtcatgt aatgaatggc   2280

tctactcaga ttgaccatat gggttttttc tttttctttc ttttattctt ctccttcttt   2340

ttttttcaga ggtgggatgg gtggagattt tttaaaaatc ccacgtgtga aagtttactg   2400

gctttattag caagttcctt tttacttcaa gctacttttt ataaaaaaga acatttttcc   2460

agtgtggttt ttaacagata atacatttct tccacattca gattagtatt cggacatgaa   2520

tccattctat aaaacacatc gtgttcatga tagtgtatat tttactactt tttgaatgtt   2580

aattttaaaa tagaagatgt cccacttgcc attaaatata gaagccaact ttttaccttt   2640

tgaaatatgg ctacatttaa aacaaaatct cacagctcgg tttttcttat ttgttgagtg   2700

ctattaccag gagaaattca aataaatatt caatttcatt atg                     2743


<210>  6577
<211>  609
<212>  PRT
<213>  Homo sapiens

<400>  6577

Met Ala Glu Tyr Leu Asp Ser Ser Arg Val Glu Val Trp Glu Lys Thr 
1               5                   10                  15


Ser Cys Ser Lys Gln Val Thr Phe Leu Val Tyr Gln Glu Gly Asp Gln 
            20                  25                  30


Leu Asn Phe Phe Pro Ala Val Asp Arg Gly Asp Gly Thr Leu Thr Pro 
        35                  40                  45


Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe His Leu His Val Leu Arg 
    50                  55                  60


Arg Lys Gly Glu His Arg Met Ser Gly Gly Ser Met Tyr Asn Ser Asp 
65                  70                  75                  80


Thr Asp Glu Asp Glu Glu Thr Glu Pro Ser Ser Ser Gly Gln Gln Ile 
                85                  90                  95


Ile Glu Asn Ser Ile Thr Met Asn Lys Met Lys Leu Leu Lys Ala Lys 
            100                 105                 110


Met Lys Asn Met Asn Leu Ser Lys Lys Pro Lys Lys Ala Val Lys Ile 
        115                 120                 125


Lys Pro His Pro Pro Val Ala Pro Arg Pro Ser Ser Gly Ser Thr Ala 
    130                 135                 140


Pro Ser Arg His Arg Leu Leu Arg Val Leu Pro Asn Ile Gly Gln Ser 
145                 150                 155                 160


Cys Ser Pro Ala Phe Gly Asn Ala Tyr Pro Pro Glu Ile Ser Arg Asn 
                165                 170                 175


Gly Ile Ser Ser Leu Ala Thr Gln Leu Ser Ala Glu Arg Tyr Ile Ser 
            180                 185                 190


Ser Ile Thr Gly Glu Phe Leu Lys Glu Asp Asn Ser Trp Glu Asn Asn 
        195                 200                 205


Thr Leu Ser His Phe Ser Ser Asn Val Lys Leu Pro Pro Gln Ile Pro 
    210                 215                 220


His Leu Glu Leu Gly Asn Asp Gln Glu Leu Ala Asp Ser Val Leu His 
225                 230                 235                 240


Leu Gly Ser Ser Leu Pro Arg Gln Thr Lys His Phe Leu Gly Asn Leu 
                245                 250                 255


Pro Ser Ser Asn Gly Asn Ile Val Leu Pro Ser Glu Glu Cys Val Thr 
            260                 265                 270


Glu Gln Ser Leu Leu Pro Lys Val Gly Ser Leu Ala Ser Phe Ala Glu 
        275                 280                 285


Gly Asn Ala Asp Glu Gln Ser Ser Gly Leu Glu Gly Ala Cys Lys Val 
    290                 295                 300


Asn Leu Glu Leu Leu Leu Thr Asn Ala Asp Lys Gly Leu Lys Ala Pro 
305                 310                 315                 320


Glu Gln His Leu Lys His Val Ala Gly Val Leu Asn Gly Glu Ser Val 
                325                 330                 335


Glu Thr Ser Val Leu Asn Tyr Arg Glu Leu Ser Pro His Lys Asn Arg 
            340                 345                 350


Leu Leu Ser Pro Leu Arg Cys Ser Ala Pro Met Ser Leu His Asn Ser 
        355                 360                 365


Leu Val Lys Pro Glu Arg Gln Ser Lys Cys Phe Glu Phe Gly Lys Leu 
    370                 375                 380


Gln Pro Ser Ser Ser Gln Ser Leu Asp Val Gln Asn Ile Thr Asp Ser 
385                 390                 395                 400


Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly Val Lys Val Asp Ser Leu 
                405                 410                 415


Gly Lys Arg Ser Asp Val Ile Ser Lys Val Glu Ala Arg Asp Ile Thr 
            420                 425                 430


Glu Met Thr Asn Lys Ala Ser Lys Glu Pro Val Gly Cys Val Asn Asn 
        435                 440                 445


Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser Thr Ser Arg Asn Arg Leu 
    450                 455                 460


Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln Asn Ser Gly Thr Gly Leu 
465                 470                 475                 480


Ser Thr Asn Leu Gln His Phe Gln Glu Glu Asn Phe Arg Lys Ser Ser 
                485                 490                 495


Pro Gln Leu Glu His Thr Gly Val Phe Leu Ser Thr His Gly Val Gly 
            500                 505                 510


Met Asn Gly Asn Asn Ala Ala Ala Gly Lys Ser Val Gly Glu Cys Thr 
        515                 520                 525


Thr His His Leu Pro Pro Val Lys Ala Pro Leu Gln Thr Lys Lys Lys 
    530                 535                 540


Thr Thr Asn His Cys Phe Leu Cys Gly Lys Lys Thr Gly Leu Ala Ser 
545                 550                 555                 560


Ser Tyr Glu Cys Arg Cys Gly Asn Asn Phe Cys Ala Ser His Arg Tyr 
                565                 570                 575


Ala Glu Thr His Gly Cys Thr Tyr Asp Tyr Lys Ser Ala Gly Arg Arg 
            580                 585                 590


Tyr Leu His Glu Ala Asn Pro Val Val Asn Ala Pro Lys Leu Pro Lys 
        595                 600                 605


Ile 



<210>  6578
<211>  3252
<212>  DNA
<213>  Homo sapiens

<400>  6578
gcgcaggtac aaaactcaaa acatgaacaa caatatatat taccaatctt caaacctggt     60

ttgcctagaa ctggaataca gttgcctgcg acatatttta gaagaactag aaaagtcaaa    120

gtaatggata acagaaaaga gcctccattc ttcaatgatg ataacatggg accattttac    180

tacagacttc atttctgtga taccatggag ctcttcattg aaacattaac tggaacatgt    240

tttgagctga gagtttcacc ttttgaaact gttatttctg tgaaagcaaa aattcgaaga    300

ttggaagacc caggagatcc tactgaagtg agtggctggc cgagtccagt gaccacatca    360

gcacattcag taatgactct tgaagctttt gtctgcccta aatgatttgg tattcccatc    420

tgtcgacaac acttaatttg gaataacatg gaacttgaaa atgattattg cttgaatgat    480

tacaacattt cagaagggtg taccttgaag ctagttttgg ctatgcgtgg cggacctata    540

aatactagaa gagttcctac agacgatcca cttaggaaga tggcagagta cttggattcc    600

agtcgagttg aggtctggga gaagacctcc tgcagcaaac aagttacatt tttggtatac    660

caagaaggag atcaattgaa tttctttcct gcagtagata ggggagatgg cactttaaca    720

ccgttatctg actcttcaaa gaaaatagat tttcatttgc atgtcctacg gagaaaagga    780

gaacatcgta tgagtggtgg ttctatgtat aattcagata cagatgagga tgaagaaact    840

gagccttctt cttctgggca acagataatt gaaaattcaa taactatgaa taagatgaag    900

ctgctgaagg ctaagatgaa gaacatgaat ctcagcaaaa agcctaagaa agctgtcaag    960

ataaaacctc acccacctgt agctcctcga ccttctagtg gttccactgc accatctcgc   1020

caccgattgt taagggtcct ccccaacatt ggtcaatctt gttcacctgc ttttgggaat   1080

gcatatccgc ccgaaatctc caggaatgga atttcaagtt tggcaactca actctctgct   1140

gagagataca tatcttctat cactggtgaa tttcttaagg aagataatag ctgggagaat   1200

aacacactgt ctcacttcag tagcaacgtc aaactacctc ctcagatacc ccatttggag   1260

ttgggaaatg accaggagct tgctgactct gttctccatc ttggatcatc cctgcctagg   1320

caaacaaaac attttttagg aaacttgcca tctagtaatg ggaacattgt cttaccttca   1380

gaagaatgtg taaccgaaca atcacttcta cctaaagtgg gctcactggc ttcatttgca   1440

gaaggaaatg ctgatgaaca gagcagcggc ttagaaggtg cgtgcaaagt gaatctggag   1500

ttgctactca ctaatgctga caaagggttg aaagctccag agcagcatct caagcatgtt   1560

gcaggagtgc tgaatgggga atcagtagag acttcagttc ttaactaccg ggaattaagt   1620

cctcacaaga atagactctt gtcacctctt cgctgttctg caccaatgtc gctacataat   1680

tctctggtga aaccagagag acagtccaaa tgttttgagt ttgggaagct acagccttct   1740

tcttctcagt cactggatgt tcaaaacata actgattctt ctttctctag gactacttgc   1800

tttcaaggtg ttaaagttga ttcacttggg aaaagatctg atgttatttc caaagttgag   1860

gctcgggata tcacagaaat gactaacaag gcttccaaag agcctgttgg ttgtgtaaat   1920

aatatcagtt ttcttgcctc actggccggg agcacaagca gaaatagatt acagagcaca   1980

cgtggggcag gcaggcttca gaactctgga actgggctgt ctacaaacct ccagcatttt   2040

caggaagaaa actttaggaa aagttctccc cagttagaac atacaggagt ttttttgtct   2100

acccatggtg ttggaatgaa tggaaataat gcagcagcag ggaaaagcgt aggagaatgt   2160

actactcatc acctcccacc tgtgaaagcc cctcttcaga caaagaagaa aacaacaaat   2220

cattgttttc tttgtggaaa gaaaacagga ctggctagta gctacgaatg cagatgtgga   2280

aacaacttct gtgcatctca tcgttatgca gaaactcatg gctgtaccta tgattacaag   2340

agtgcaggga ggagatactt gcacgaggca aatcctgtgg ttaatgcacc aaagcttcca   2400

aaaatctaac tcttcctcta catcttactg ttctgcccgg gattcgtatt ataatgacag   2460

aagaaatgtt gtttagacta ttatttttgt tcgactctaa aagatttgcc aaataacaaa   2520

agcatacaat gcatactgtt ggagaacaag aatgctactg tattttacat ctttatttct   2580

tggtgaaaca aaagttttaa aagtagtttt aacaacttta cactggaatg atttagcttt   2640

gttattgcat gtcttgtgtt aagtgttttg tatatgatat tgcagtttta ctaggcaaat   2700

cttcaaaaga tgcactttag gaaacgaaat atttcctaaa taaccaggct tccacattgt   2760

acagaatgag cagtcatgta atgaatggct ctactcagat tgaccatatg ggttttttct   2820

ttttctttct tttattcttc tccttctttt tttttcagag gtgggatggg tggagatttt   2880

ttaaaaatcc cacgtgtgaa agtttactgg ctttattagc aagttccttt ttacttcaag   2940

ctacttttta taaaaaagaa catttttcca gtgtggtttt taacagataa tacatttctt   3000

ccacattcag attagtattc ggacatgaat ccattctata aaacacatcg tgttcatgat   3060

agtgtatatt ttactacttt ttgaatgtta attttaaaat agaagatgtc ccacttgcca   3120

ttaaatatag aagccaactt tttacctttt gaaatatggc tacatttaaa acaaaatctc   3180

acagctcggt ttttcttatt tgttgagtgc tattaccagg agaaattcaa ataaatattc   3240

aatttcatta tg                                                       3252


<210>  6579
<211>  653
<212>  PRT
<213>  Homo sapiens

<400>  6579

Met Glu Leu Glu Asn Asp Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu 
1               5                   10                  15


Gly Cys Thr Leu Lys Leu Val Leu Ala Met Arg Gly Gly Pro Ile Asn 
            20                  25                  30


Thr Arg Arg Val Pro Thr Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr 
        35                  40                  45


Leu Asp Ser Ser Arg Val Glu Val Trp Glu Lys Thr Ser Cys Ser Lys 
    50                  55                  60


Gln Val Thr Phe Leu Val Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe 
65                  70                  75                  80


Pro Ala Val Asp Arg Gly Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser 
                85                  90                  95


Ser Lys Lys Ile Asp Phe His Leu His Val Leu Arg Arg Lys Gly Glu 
            100                 105                 110


His Arg Met Ser Gly Gly Ser Met Tyr Asn Ser Asp Thr Asp Glu Asp 
        115                 120                 125


Glu Glu Thr Glu Pro Ser Ser Ser Gly Gln Gln Ile Ile Glu Asn Ser 
    130                 135                 140


Ile Thr Met Asn Lys Met Lys Leu Leu Lys Ala Lys Met Lys Asn Met 
145                 150                 155                 160


Asn Leu Ser Lys Lys Pro Lys Lys Ala Val Lys Ile Lys Pro His Pro 
                165                 170                 175


Pro Val Ala Pro Arg Pro Ser Ser Gly Ser Thr Ala Pro Ser Arg His 
            180                 185                 190


Arg Leu Leu Arg Val Leu Pro Asn Ile Gly Gln Ser Cys Ser Pro Ala 
        195                 200                 205


Phe Gly Asn Ala Tyr Pro Pro Glu Ile Ser Arg Asn Gly Ile Ser Ser 
    210                 215                 220


Leu Ala Thr Gln Leu Ser Ala Glu Arg Tyr Ile Ser Ser Ile Thr Gly 
225                 230                 235                 240


Glu Phe Leu Lys Glu Asp Asn Ser Trp Glu Asn Asn Thr Leu Ser His 
                245                 250                 255


Phe Ser Ser Asn Val Lys Leu Pro Pro Gln Ile Pro His Leu Glu Leu 
            260                 265                 270


Gly Asn Asp Gln Glu Leu Ala Asp Ser Val Leu His Leu Gly Ser Ser 
        275                 280                 285


Leu Pro Arg Gln Thr Lys His Phe Leu Gly Asn Leu Pro Ser Ser Asn 
    290                 295                 300


Gly Asn Ile Val Leu Pro Ser Glu Glu Cys Val Thr Glu Gln Ser Leu 
305                 310                 315                 320


Leu Pro Lys Val Gly Ser Leu Ala Ser Phe Ala Glu Gly Asn Ala Asp 
                325                 330                 335


Glu Gln Ser Ser Gly Leu Glu Gly Ala Cys Lys Val Asn Leu Glu Leu 
            340                 345                 350


Leu Leu Thr Asn Ala Asp Lys Gly Leu Lys Ala Pro Glu Gln His Leu 
        355                 360                 365


Lys His Val Ala Gly Val Leu Asn Gly Glu Ser Val Glu Thr Ser Val 
    370                 375                 380


Leu Asn Tyr Arg Glu Leu Ser Pro His Lys Asn Arg Leu Leu Ser Pro 
385                 390                 395                 400


Leu Arg Cys Ser Ala Pro Met Ser Leu His Asn Ser Leu Val Lys Pro 
                405                 410                 415


Glu Arg Gln Ser Lys Cys Phe Glu Phe Gly Lys Leu Gln Pro Ser Ser 
            420                 425                 430


Ser Gln Ser Leu Asp Val Gln Asn Ile Thr Asp Ser Ser Phe Ser Arg 
        435                 440                 445


Thr Thr Cys Phe Gln Gly Val Lys Val Asp Ser Leu Gly Lys Arg Ser 
    450                 455                 460


Asp Val Ile Ser Lys Val Glu Ala Arg Asp Ile Thr Glu Met Thr Asn 
465                 470                 475                 480


Lys Ala Ser Lys Glu Pro Val Gly Cys Val Asn Asn Ile Ser Phe Leu 
                485                 490                 495


Ala Ser Leu Ala Gly Ser Thr Ser Arg Asn Arg Leu Gln Ser Thr Arg 
            500                 505                 510


Gly Ala Gly Arg Leu Gln Asn Ser Gly Thr Gly Leu Ser Thr Asn Leu 
        515                 520                 525


Gln His Phe Gln Glu Glu Asn Phe Arg Lys Ser Ser Pro Gln Leu Glu 
    530                 535                 540


His Thr Gly Val Phe Leu Ser Thr His Gly Val Gly Met Asn Gly Asn 
545                 550                 555                 560


Asn Ala Ala Ala Gly Lys Ser Val Gly Glu Cys Thr Thr His His Leu 
                565                 570                 575


Pro Pro Val Lys Ala Pro Leu Gln Thr Lys Lys Lys Thr Thr Asn His 
            580                 585                 590


Cys Phe Leu Cys Gly Lys Lys Thr Gly Leu Ala Ser Ser Tyr Glu Cys 
        595                 600                 605


Arg Cys Gly Asn Asn Phe Cys Ala Ser His Arg Tyr Ala Glu Thr His 
    610                 615                 620


Gly Cys Thr Tyr Asp Tyr Lys Ser Ala Gly Arg Arg Tyr Leu His Glu 
625                 630                 635                 640


Ala Asn Pro Val Val Asn Ala Pro Lys Leu Pro Lys Ile 
                645                 650


<210>  6580
<211>  3323
<212>  DNA
<213>  Homo sapiens

<400>  6580
tgaagttgct cgccgggtcg ttgggccctg tcgacctgta ggcgggcgag cgagccagcg     60

gacaagactg cgggtgctga tctccgagtc gctgttgtca cgcggactgc tgtcctccag    120

attcaggccg gtgggtctgg ggagcccgga ttggtcttgg aggagcaacg gctgcgcagg    180

tacaaaactc aaaacatgaa caacaatata tattaccaat cttcaaacct ggtttgccta    240

gaactggaat acagttgcct gcgacatatt ttagaagaac tagaaaagtc aaagtaatgg    300

ataacagaaa agagcctcca ttcttcaatg atgataacat gggaccattt tactacagac    360

ttcatttctg tgataccatg gagctcttca ttgaaacatt aactggaaca tgttttgagc    420

tgagagtttc accttttgaa actgttattt ctgtgaaagc aaaaattcga agattggaag    480

gtattcccat ctgtcgacaa cacttaattt ggaataacat ggaacttgaa aatgattatt    540

gcttgaatga ttacaacatt tcagaagggt gtaccttgaa gctagttttg gctatgcgtg    600

gcggacctat aaatactaga agagttccta cagacgatcc acttaggaag atggcagagt    660

acttggattc cagtcgagtt gaggtctggg agaagacctc ctgcagcaaa caagttacat    720

ttttggtata ccaagaagga gatcaattga atttctttcc tgcagtagat aggggagatg    780

gcactttaac accgttatct gactcttcaa agaaaataga ttttcatttg catgtcctac    840

ggagaaaagg agaacatcgt atgagtggtg gttctatgta taattcagat acagatgagg    900

atgaagaaac tgagccttct tcttctgggc aacagataat tgaaaattca ataactatga    960

ataagatgaa gctgctgaag gctaagatga agaacatgaa tctcagcaaa aagcctaaga   1020

aagctgtcaa gataaaacct cacccacctg tagctcctcg accttctagt ggttccactg   1080

caccatctcg ccaccgattg ttaagggtcc tccccaacat tggtcaatct tgttcacctg   1140

cttttgggaa tgcatatccg cccgaaatct ccaggaatgg aatttcaagt ttggcaactc   1200

aactctctgc tgagagatac atatcttcta tcactggtga atttcttaag gaagataata   1260

gctgggagaa taacacactg tctcacttca gtagcaacgt caaactacct cctcagatac   1320

cccatttgga gttgggaaat gaccaggagc ttgctgactc tgttctccat cttggatcat   1380

ccctgcctag gcaaacaaaa cattttttag gaaacttgcc atctagtaat gggaacattg   1440

tcttaccttc agaagaatgt gtaaccgaac aatcacttct acctaaagtg ggctcactgg   1500

cttcatttgc agaaggaaat gctgatgaac agagcagcgg cttagaaggt gcgtgcaaag   1560

tgaatctgga gttgctactc actaatgctg acaaagggtt gaaagctcca gagcagcatc   1620

tcaagcatgt tgcaggagtg ctgaatgggg aatcagtaga gacttcagtt cttaactacc   1680

gggaattaag tcctcacaag aatagactct tgtcacctct tcgctgttct gcaccaatgt   1740

cgctacataa ttctctggtg aaaccagaga gacagtccaa atgttttgag tttgggaagc   1800

tacagccttc ttcttctcag tcactggatg ttcaaaacat aactgattct tctttctcta   1860

ggactacttg ctttcaaggt gttaaagttg attcacttgg gaaaagatct gatgttattt   1920

ccaaagttga ggctcgggat atcacagaaa tgactaacaa ggcttccaaa gagcctgttg   1980

gttgtgtaaa taatatcagt tttcttgcct cactggccgg gagcacaagc agaaatagat   2040

tacagagcac acgtggggca ggcaggcttc agaactctgg aactgggctg tctacaaacc   2100

tccagcattt tcaggaagaa aactttagga aaagttctcc ccagttagaa catacaggag   2160

tttttttgtc tacccatggt gttggaatga atggaaataa tgcagcagca gggaaaagcg   2220

taggagaatg tactactcat cacctcccac ctgtgaaagc ccctcttcag acaaagaaga   2280

aaacaacaaa tcattgtttt ctttgtggaa agaaaacagg actggctagt agctacgaat   2340

gcagatgtgg aaacaacttc tgtgcatctc atcgttatgc agaaactcat ggctgtacct   2400

atgattacaa gagtgcaggg aggagatact tgcacgaggc aaatcctgtg gttaatgcac   2460

caaagcttcc aaaaatctaa ctcttcctct acatcttact gttctgcccg ggattcgtat   2520

tataatgaca gaagaaatgt tgtttagact attatttttg ttcgactcta aaagatttgc   2580

caaataacaa aagcatacaa tgcatactgt tggagaacaa gaatgctact gtattttaca   2640

tctttatttc ttggtgaaac aaaagtttta aaagtagttt taacaacttt acactggaat   2700

gatttagctt tgttattgca tgtcttgtgt taagtgtttt gtatatgata ttgcagtttt   2760

actaggcaaa tcttcaaaag atgcacttta ggaaacgaaa tatttcctaa ataaccaggc   2820

ttccacattg tacagaatga gcagtcatgt aatgaatggc tctactcaga ttgaccatat   2880

gggttttttc tttttctttc ttttattctt ctccttcttt ttttttcaga ggtgggatgg   2940

gtggagattt tttaaaaatc ccacgtgtga aagtttactg gctttattag caagttcctt   3000

tttacttcaa gctacttttt ataaaaaaga acatttttcc agtgtggttt ttaacagata   3060

atacatttct tccacattca gattagtatt cggacatgaa tccattctat aaaacacatc   3120

gtgttcatga tagtgtatat tttactactt tttgaatgtt aattttaaaa tagaagatgt   3180

cccacttgcc attaaatata gaagccaact ttttaccttt tgaaatatgg ctacatttaa   3240

aacaaaatct cacagctcgg tttttcttat ttgttgagtg ctattaccag gagaaattca   3300

aataaatatt caatttcatt atg                                           3323


<210>  6581
<211>  727
<212>  PRT
<213>  Homo sapiens

<400>  6581

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Val Pro Thr 
            100                 105                 110


Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr Leu Asp Ser Ser Arg Val 
        115                 120                 125


Glu Val Trp Glu Lys Thr Ser Cys Ser Lys Gln Val Thr Phe Leu Val 
    130                 135                 140


Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe Pro Ala Val Asp Arg Gly 
145                 150                 155                 160


Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe 
                165                 170                 175


His Leu His Val Leu Arg Arg Lys Gly Glu His Arg Met Ser Gly Gly 
            180                 185                 190


Ser Met Tyr Asn Ser Asp Thr Asp Glu Asp Glu Glu Thr Glu Pro Ser 
        195                 200                 205


Ser Ser Gly Gln Gln Ile Ile Glu Asn Ser Ile Thr Met Asn Lys Met 
    210                 215                 220


Lys Leu Leu Lys Ala Lys Met Lys Asn Met Asn Leu Ser Lys Lys Pro 
225                 230                 235                 240


Lys Lys Ala Val Lys Ile Lys Pro His Pro Pro Val Ala Pro Arg Pro 
                245                 250                 255


Ser Ser Gly Ser Thr Ala Pro Ser Arg His Arg Leu Leu Arg Val Leu 
            260                 265                 270


Pro Asn Ile Gly Gln Ser Cys Ser Pro Ala Phe Gly Asn Ala Tyr Pro 
        275                 280                 285


Pro Glu Ile Ser Arg Asn Gly Ile Ser Ser Leu Ala Thr Gln Leu Ser 
    290                 295                 300


Ala Glu Arg Tyr Ile Ser Ser Ile Thr Gly Glu Phe Leu Lys Glu Asp 
305                 310                 315                 320


Asn Ser Trp Glu Asn Asn Thr Leu Ser His Phe Ser Ser Asn Val Lys 
                325                 330                 335


Leu Pro Pro Gln Ile Pro His Leu Glu Leu Gly Asn Asp Gln Glu Leu 
            340                 345                 350


Ala Asp Ser Val Leu His Leu Gly Ser Ser Leu Pro Arg Gln Thr Lys 
        355                 360                 365


His Phe Leu Gly Asn Leu Pro Ser Ser Asn Gly Asn Ile Val Leu Pro 
    370                 375                 380


Ser Glu Glu Cys Val Thr Glu Gln Ser Leu Leu Pro Lys Val Gly Ser 
385                 390                 395                 400


Leu Ala Ser Phe Ala Glu Gly Asn Ala Asp Glu Gln Ser Ser Gly Leu 
                405                 410                 415


Glu Gly Ala Cys Lys Val Asn Leu Glu Leu Leu Leu Thr Asn Ala Asp 
            420                 425                 430


Lys Gly Leu Lys Ala Pro Glu Gln His Leu Lys His Val Ala Gly Val 
        435                 440                 445


Leu Asn Gly Glu Ser Val Glu Thr Ser Val Leu Asn Tyr Arg Glu Leu 
    450                 455                 460


Ser Pro His Lys Asn Arg Leu Leu Ser Pro Leu Arg Cys Ser Ala Pro 
465                 470                 475                 480


Met Ser Leu His Asn Ser Leu Val Lys Pro Glu Arg Gln Ser Lys Cys 
                485                 490                 495


Phe Glu Phe Gly Lys Leu Gln Pro Ser Ser Ser Gln Ser Leu Asp Val 
            500                 505                 510


Gln Asn Ile Thr Asp Ser Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly 
        515                 520                 525


Val Lys Val Asp Ser Leu Gly Lys Arg Ser Asp Val Ile Ser Lys Val 
    530                 535                 540


Glu Ala Arg Asp Ile Thr Glu Met Thr Asn Lys Ala Ser Lys Glu Pro 
545                 550                 555                 560


Val Gly Cys Val Asn Asn Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser 
                565                 570                 575


Thr Ser Arg Asn Arg Leu Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln 
            580                 585                 590


Asn Ser Gly Thr Gly Leu Ser Thr Asn Leu Gln His Phe Gln Glu Glu 
        595                 600                 605


Asn Phe Arg Lys Ser Ser Pro Gln Leu Glu His Thr Gly Val Phe Leu 
    610                 615                 620


Ser Thr His Gly Val Gly Met Asn Gly Asn Asn Ala Ala Ala Gly Lys 
625                 630                 635                 640


Ser Val Gly Glu Cys Thr Thr His His Leu Pro Pro Val Lys Ala Pro 
                645                 650                 655


Leu Gln Thr Lys Lys Lys Thr Thr Asn His Cys Phe Leu Cys Gly Lys 
            660                 665                 670


Lys Thr Gly Leu Ala Ser Ser Tyr Glu Cys Arg Cys Gly Asn Asn Phe 
        675                 680                 685


Cys Ala Ser His Arg Tyr Ala Glu Thr His Gly Cys Thr Tyr Asp Tyr 
    690                 695                 700


Lys Ser Ala Gly Arg Arg Tyr Leu His Glu Ala Asn Pro Val Val Asn 
705                 710                 715                 720


Ala Pro Lys Leu Pro Lys Ile 
                725


<210>  6582
<211>  2071
<212>  DNA
<213>  Homo sapiens

<400>  6582
gtgaagttgc tcgccgggtc gttgggccct gtcgacctgt aggcgggcga gcgagccaac     60

gccggccgct gctgcccggg gaccggagcg gcgggccgcc tttgcccagg acacacgctc    120

tggcgtttgt tcctttgggc gtgacgccag cttcaacggg tacgcggctt tcccgacggg    180

tgctgatctc cgagtcgctg ttgtcacgcg gactgctgtc ctccagattc aggccggtgg    240

gtctggggag cccggattgg tcttggagga gcaacggctg cgcaggtaca aaactcaaaa    300

catgaacaac aatatatatt accaatcttc aaacctggtt tgcctagaac tggaatacag    360

ttgcctgcga catattttag aagaactaga aaagtcaaag taatggataa cagaaaagag    420

cctccattct tcaatgatga taacatggga ccattttact acagacttca tttctgtgat    480

accatggagc tcttcattga aacattaact ggaacatgtt ttgagctgag agtttcacct    540

tttgaaactg ttatttctgt gaaagcaaaa attcgaagat tggaaggtat tcccatctgt    600

cgacaacact taatttggaa taacatggaa cttgaaaatg attattgctt gaatgattac    660

aacatttcag aagggtgtac cttgaagcta gttttggcta tgcgtggcgg acctataaat    720

actagaagag ttcctacaga cgatccactt aggaagatgg cagagtactt ggattccagt    780

cgagttgagg tctgggagaa gacctcctgc agcaaacaag ttacattttt ggtataccaa    840

gaaggagatc aattgaattt ctttcctgca gtagataggg gagatggcac tttaacaccg    900

ttatctgact cttcaaagaa aatagatttt catttgcatg tcctacggag aaaaggagaa    960

catcgtatga ggagaatgta ctactcatca cctcccacct gtgaaagccc ctcttcagac   1020

aaagaagaaa acaacaaatc attgttttct ttgtggaaag aaaacaggac tggctagtag   1080

ctacgaatgc agatgtggaa acaacttctg tgcatctcat cgttatgcag aaactcatgg   1140

ctgtacctat gattacaaga gtgcagggag gagatacttg cacgaggcaa atcctgtggt   1200

taatgcacca aagcttccaa aaatctaact cttcctctac atcttactgt tctgcccggg   1260

attcgtatta taatgacaga agaaatgttg tttagactat tatttttgtt cgactctaaa   1320

agatttgcca aataacaaaa gcatacaatg catactgttg gagaacaaga atgctactgt   1380

attttacatc tttatttctt ggtgaaacaa aagttttaaa agtagtttta acaactttac   1440

actggaatga tttagctttg ttattgcatg tcttgtgtta agtgttttgt atatgatatt   1500

gcagttttac taggcaaatc ttcaaaagat gcactttagg aaacgaaata tttcctaaat   1560

aaccaggctt ccacattgta cagaatgagc agtcatgtaa tgaatggctc tactcagatt   1620

gaccatatgg gttttttctt tttctttctt ttattcttct ccttcttttt ttttcagagg   1680

tgggatgggt ggagattttt taaaaatccc acgtgtgaaa gtttactggc tttattagca   1740

agttcctttt tacttcaagc tactttttat aaaaaagaac atttttccag tgtggttttt   1800

aacagataat acatttcttc cacattcaga ttagtattcg gacatgaatc cattctataa   1860

aacacatcgt gttcatgata gtgtatattt tactactttt tgaatgttaa ttttaaaata   1920

gaagatgtcc cacttgccat taaatataga agccaacttt ttaccttttg aaatatggct   1980

acatttaaaa caaaatctca cagctcggtt tttcttattt gttgagtgct attaccagga   2040

gaaattcaaa taaatattca atttcattat g                                  2071


<210>  6583
<211>  224
<212>  PRT
<213>  Homo sapiens

<400>  6583

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Val Pro Thr 
            100                 105                 110


Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr Leu Asp Ser Ser Arg Val 
        115                 120                 125


Glu Val Trp Glu Lys Thr Ser Cys Ser Lys Gln Val Thr Phe Leu Val 
    130                 135                 140


Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe Pro Ala Val Asp Arg Gly 
145                 150                 155                 160


Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe 
                165                 170                 175


His Leu His Val Leu Arg Arg Lys Gly Glu His Arg Met Arg Arg Met 
            180                 185                 190


Tyr Tyr Ser Ser Pro Pro Thr Cys Glu Ser Pro Ser Ser Asp Lys Glu 
        195                 200                 205


Glu Asn Asn Lys Ser Leu Phe Ser Leu Trp Lys Glu Asn Arg Thr Gly 
    210                 215                 220


<210>  6584
<211>  3279
<212>  DNA
<213>  Homo sapiens

<400>  6584
aggtggtgtc acaaaggggc ggggcgcggc ggcagcggag cgttgtcggc cagtgccttc     60

cgtgaagttg ctcgccgggt cgttgggccc tgtcgacctg taggcgggcg agcgagccag    120

cggacaagac tgcgggtaca aaactcaaaa catgaacaac aatatatatt accaatcttc    180

aaacctggtt tgcctagaac tggaatacag ttgcctgcga catattttag aagaactaga    240

aaagtcaaag taatggataa cagaaaagag cctccattct tcaatgatga taacatggga    300

ccattttact acagacttca tttctgtgat accatggagc tcttcattga aacattaact    360

ggaacatgtt ttgagctgag agtttcacct tttgaaactg ttatttctgt gaaagcaaaa    420

attcgaagat tggaaggtat tcccatctgt cgacaacact taatttggaa taacatggaa    480

cttgaaaatg attattgctt gaatgattac aacatttcag aagggtgtac cttgaagcta    540

gttttggcta tgcgtggcgg acctataaat actagaagag ttcctacaga cgatccactt    600

aggaagatgg cagagtactt ggattccagt cgagttgagg tctgggagaa gacctcctgc    660

agcaaacaag ttacattttt ggtataccaa gaaggagatc aattgaattt ctttcctgca    720

gtagataggg gagatggcac tttaacaccg ttatctgact cttcaaagaa aatagatttt    780

catttgcatg tcctacggag aaaaggagaa catcgtatga gtggtggttc tatgtataat    840

tcagatacag atgaggatga agaaactgag ccttcttctt ctgggcaaca gataattgaa    900

aattcaataa ctatgaataa gatgaagctg ctgaaggcta agatgaagaa catgaatctc    960

agcaaaaagc ctaagaaagc tgtcaagata aaacctcacc cacctgtagc tcctcgacct   1020

tctagtggtt ccactgcacc atctcgccac cgattgttaa gggtcctccc caacattggt   1080

caatcttgtt cacctgcttt tgggaatgca tatccgcccg aaatctccag gaatggaatt   1140

tcaagtttgg caactcaact ctctgctgag agatacatat cttctatcac tggtgaattt   1200

cttaaggaag ataatagctg ggagaataac acactgtctc acttcagtag caacgtcaaa   1260

ctacctcctc agatacccca tttggagttg ggaaatgacc aggagcttgc tgactctgtt   1320

ctccatcttg gatcatccct gcctaggcaa acaaaacatt ttttaggaaa cttgccatct   1380

agtaatggga acattgtctt accttcagaa gaatgtgtaa ccgaacaatc acttctacct   1440

aaagtgggct cactggcttc atttgcagaa ggaaatgctg atgaacagag cagcggctta   1500

gaaggtgcgt gcaaagtgaa tctggagttg ctactcacta atgctgacaa agggttgaaa   1560

gctccagagc agcatctcaa gcatgttgca ggagtgctga atggggaatc agtagagact   1620

tcagttctta actaccggga attaagtcct cacaagaata gactcttgtc acctcttcgc   1680

tgttctgcac caatgtcgct acataattct ctggtgaaac cagagagaca gtccaaatgt   1740

tttgagtttg ggaagctaca gccttcttct tctcagtcac tggatgttca aaacataact   1800

gattcttctt tctctaggac tacttgcttt caaggtgtta aagttgattc acttgggaaa   1860

agatctgatg ttatttccaa agttgaggct cgggatatca cagaaatgac taacaaggct   1920

tccaaagagc ctgttggttg tgtaaataat atcagttttc ttgcctcact ggccgggagc   1980

acaagcagaa atagattaca gagcacacgt ggggcaggca ggcttcagaa ctctggaact   2040

gggctgtcta caaacctcca gcattttcag gaagaaaact ttaggaaaag ttctccccag   2100

ttagaacata caggagtttt tttgtctacc catggtgttg gaatgaatgg aaataatgca   2160

gcagcaggga aaagcgtagg agaatgtact actcatcacc tcccacctgt gaaagcccct   2220

cttcagacaa agaagaaaac aacaaatcat tgttttcttt gtggaaagaa aacaggactg   2280

gctagtagct acgaatgcag atgtggaaac aacttctgtg catctcatcg ttatgcagaa   2340

actcatggct gtacctatga ttacaagagt gcagggagga gatacttgca cgaggcaaat   2400

cctgtggtta atgcaccaaa gcttccaaaa atctaactct tcctctacat cttactgttc   2460

tgcccgggat tcgtattata atgacagaag aaatgttgtt tagactatta tttttgttcg   2520

actctaaaag atttgccaaa taacaaaagc atacaatgca tactgttgga gaacaagaat   2580

gctactgtat tttacatctt tatttcttgg tgaaacaaaa gttttaaaag tagttttaac   2640

aactttacac tggaatgatt tagctttgtt attgcatgtc ttgtgttaag tgttttgtat   2700

atgatattgc agttttacta ggcaaatctt caaaagatgc actttaggaa acgaaatatt   2760

tcctaaataa ccaggcttcc acattgtaca gaatgagcag tcatgtaatg aatggctcta   2820

ctcagattga ccatatgggt tttttctttt tctttctttt attcttctcc ttcttttttt   2880

ttcagaggtg ggatgggtgg agatttttta aaaatcccac gtgtgaaagt ttactggctt   2940

tattagcaag ttccttttta cttcaagcta ctttttataa aaaagaacat ttttccagtg   3000

tggtttttaa cagataatac atttcttcca cattcagatt agtattcgga catgaatcca   3060

ttctataaaa cacatcgtgt tcatgatagt gtatatttta ctactttttg aatgttaatt   3120

ttaaaataga agatgtccca cttgccatta aatatagaag ccaacttttt accttttgaa   3180

atatggctac atttaaaaca aaatctcaca gctcggtttt tcttatttgt tgagtgctat   3240

taccaggaga aattcaaata aatattcaat ttcattatg                          3279


<210>  6585
<211>  727
<212>  PRT
<213>  Homo sapiens

<400>  6585

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Val Pro Thr 
            100                 105                 110


Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr Leu Asp Ser Ser Arg Val 
        115                 120                 125


Glu Val Trp Glu Lys Thr Ser Cys Ser Lys Gln Val Thr Phe Leu Val 
    130                 135                 140


Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe Pro Ala Val Asp Arg Gly 
145                 150                 155                 160


Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe 
                165                 170                 175


His Leu His Val Leu Arg Arg Lys Gly Glu His Arg Met Ser Gly Gly 
            180                 185                 190


Ser Met Tyr Asn Ser Asp Thr Asp Glu Asp Glu Glu Thr Glu Pro Ser 
        195                 200                 205


Ser Ser Gly Gln Gln Ile Ile Glu Asn Ser Ile Thr Met Asn Lys Met 
    210                 215                 220


Lys Leu Leu Lys Ala Lys Met Lys Asn Met Asn Leu Ser Lys Lys Pro 
225                 230                 235                 240


Lys Lys Ala Val Lys Ile Lys Pro His Pro Pro Val Ala Pro Arg Pro 
                245                 250                 255


Ser Ser Gly Ser Thr Ala Pro Ser Arg His Arg Leu Leu Arg Val Leu 
            260                 265                 270


Pro Asn Ile Gly Gln Ser Cys Ser Pro Ala Phe Gly Asn Ala Tyr Pro 
        275                 280                 285


Pro Glu Ile Ser Arg Asn Gly Ile Ser Ser Leu Ala Thr Gln Leu Ser 
    290                 295                 300


Ala Glu Arg Tyr Ile Ser Ser Ile Thr Gly Glu Phe Leu Lys Glu Asp 
305                 310                 315                 320


Asn Ser Trp Glu Asn Asn Thr Leu Ser His Phe Ser Ser Asn Val Lys 
                325                 330                 335


Leu Pro Pro Gln Ile Pro His Leu Glu Leu Gly Asn Asp Gln Glu Leu 
            340                 345                 350


Ala Asp Ser Val Leu His Leu Gly Ser Ser Leu Pro Arg Gln Thr Lys 
        355                 360                 365


His Phe Leu Gly Asn Leu Pro Ser Ser Asn Gly Asn Ile Val Leu Pro 
    370                 375                 380


Ser Glu Glu Cys Val Thr Glu Gln Ser Leu Leu Pro Lys Val Gly Ser 
385                 390                 395                 400


Leu Ala Ser Phe Ala Glu Gly Asn Ala Asp Glu Gln Ser Ser Gly Leu 
                405                 410                 415


Glu Gly Ala Cys Lys Val Asn Leu Glu Leu Leu Leu Thr Asn Ala Asp 
            420                 425                 430


Lys Gly Leu Lys Ala Pro Glu Gln His Leu Lys His Val Ala Gly Val 
        435                 440                 445


Leu Asn Gly Glu Ser Val Glu Thr Ser Val Leu Asn Tyr Arg Glu Leu 
    450                 455                 460


Ser Pro His Lys Asn Arg Leu Leu Ser Pro Leu Arg Cys Ser Ala Pro 
465                 470                 475                 480


Met Ser Leu His Asn Ser Leu Val Lys Pro Glu Arg Gln Ser Lys Cys 
                485                 490                 495


Phe Glu Phe Gly Lys Leu Gln Pro Ser Ser Ser Gln Ser Leu Asp Val 
            500                 505                 510


Gln Asn Ile Thr Asp Ser Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly 
        515                 520                 525


Val Lys Val Asp Ser Leu Gly Lys Arg Ser Asp Val Ile Ser Lys Val 
    530                 535                 540


Glu Ala Arg Asp Ile Thr Glu Met Thr Asn Lys Ala Ser Lys Glu Pro 
545                 550                 555                 560


Val Gly Cys Val Asn Asn Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser 
                565                 570                 575


Thr Ser Arg Asn Arg Leu Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln 
            580                 585                 590


Asn Ser Gly Thr Gly Leu Ser Thr Asn Leu Gln His Phe Gln Glu Glu 
        595                 600                 605


Asn Phe Arg Lys Ser Ser Pro Gln Leu Glu His Thr Gly Val Phe Leu 
    610                 615                 620


Ser Thr His Gly Val Gly Met Asn Gly Asn Asn Ala Ala Ala Gly Lys 
625                 630                 635                 640


Ser Val Gly Glu Cys Thr Thr His His Leu Pro Pro Val Lys Ala Pro 
                645                 650                 655


Leu Gln Thr Lys Lys Lys Thr Thr Asn His Cys Phe Leu Cys Gly Lys 
            660                 665                 670


Lys Thr Gly Leu Ala Ser Ser Tyr Glu Cys Arg Cys Gly Asn Asn Phe 
        675                 680                 685


Cys Ala Ser His Arg Tyr Ala Glu Thr His Gly Cys Thr Tyr Asp Tyr 
    690                 695                 700


Lys Ser Ala Gly Arg Arg Tyr Leu His Glu Ala Asn Pro Val Val Asn 
705                 710                 715                 720


Ala Pro Lys Leu Pro Lys Ile 
                725


<210>  6586
<211>  660
<212>  DNA
<213>  Homo sapiens

<400>  6586
tgttcagtac acatttgaga gaaggcttca gagaggagtt gataattgat gatgtcttac     60

aggataagtc aaattctact gggttgacaa ggtagagttt actttagaag agattgcaga    120

tgtggaagga cttggtacat ccttcgggga gaatgtacta ctcatcacct cccacctgtg    180

aaagcccctc ttcagacaaa gaagaaaaca acaaatcatt gttttctttg tggaaagaaa    240

acaggactgg ctagtagcta cgaatgcagg caggttggcg agctggagaa gctcagatgc    300

tttctctgtg ataacccagc ttggggatta tgcaaaataa aatatttaaa ttgcctgttt    360

ataacatcat taagatgatg ttcaatagct atcttcagtt gaacttctaa ttggctgaag    420

taaagaacaa gtagatagct catgggtttc caaaagacaa aaacagatcc ttccttgtcc    480

tttaagttag gaggtttaaa ccaatctgag agtgtacctt tttcgtctta tgatgaacct    540

gcttggattt tgtttgagtg gcaccttgga agaacccctc cctgaatatt ctattaaaaa    600

tttaattaaa aaattaaaag ttaatataaa atagatgaat aatatatttc caaaaaagta    660


<210>  6587
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  6587

Met Trp Lys Asp Leu Val His Pro Ser Gly Arg Met Tyr Tyr Ser Ser 
1               5                   10                  15


Pro Pro Thr Cys Glu Ser Pro Ser Ser Asp Lys Glu Glu Asn Asn Lys 
            20                  25                  30


Ser Leu Phe Ser Leu Trp Lys Glu Asn Arg Thr Gly 
        35                  40


<210>  6588
<211>  1263
<212>  DNA
<213>  Homo sapiens

<400>  6588
gccatctagt aatgggaaca ttgtcttacc ttcagaagaa tgtgtaaccg aacaatcact     60

tctacctaaa gtgggctcac tggcttcatt tgcagaagga aatgctgatg aacagagcag    120

cggcttagaa ggtgcgtgca aagtgaatct ggagttgcta ctcactaatg ctgacaaagg    180

gttgaaagct ccagagcagc atctcaagca tgttgcagga gtgctgaatg gggaatcagt    240

agagacttca gttcttaact accgggaatt aagtcctcac aagaatagac tcttgtcacc    300

tcttcgctgt tctgcaccaa tgtcgctaca taattctctg gtgaaaccag agagacagtc    360

caaatgtttt gagtttggga agctacagcc ttcttcttct cagtcactgg atgttcaaaa    420

cataactgat tcttctttct ctaggactac ttgctttcaa ggtgttaaag ttgattcact    480

tgggaaaaga tctgatgtta tttccaaagt tgaggctcgg gatatcacag aaatgactaa    540

caaggcttcc aaagagcctg ttggttgtgt aaataatatc agttttcttg cctcactggc    600

cgggagcaca agcagaaata gattacagag cacacgtggg gcaggcaggc ttcagaactc    660

tggaactggg ctgtctacaa acctccagca ttttcaggaa gaaaacttta ggaaaagttc    720

tccccagtta gaacatacag gagttttttt ggagaatgta ctactcatca cctcccacct    780

gtgaaagccc ctcttcagac aaagaagaaa acaacaaatc attgttttct ttgtggaaag    840

aaaacaggac tggctagtag ctacgaatgc aggcaggttg gcgagctgga gaagctcaga    900

tgctttctct gtgataaccc agcttgggga ttatgcaaaa taaaatattt aaattgcctg    960

tttataacat cattaagatg atgttcaata gctatcttca gttgaacttc taattggctg   1020

aagtaaagaa caagtagata gctcatgggt ttccaaaaga caaaaacaga tccttccttg   1080

tcctttaagt taggaggttt aaaccaatct gagagtgtac ctttttcgtc ttatgatgaa   1140

cctgcttgga ttttgtttga gtggcacctt ggaagaaccc ctccctgaat attctattaa   1200

aaatttaatt aaaaaattaa aagttaatat aaaatagatg aataatatat ttccaaaaaa   1260

gta                                                                 1263


<210>  6589
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  6589

Met Ser Leu His Asn Ser Leu Val Lys Pro Glu Arg Gln Ser Lys Cys 
1               5                   10                  15


Phe Glu Phe Gly Lys Leu Gln Pro Ser Ser Ser Gln Ser Leu Asp Val 
            20                  25                  30


Gln Asn Ile Thr Asp Ser Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly 
        35                  40                  45


Val Lys Val Asp Ser Leu Gly Lys Arg Ser Asp Val Ile Ser Lys Val 
    50                  55                  60


Glu Ala Arg Asp Ile Thr Glu Met Thr Asn Lys Ala Ser Lys Glu Pro 
65                  70                  75                  80


Val Gly Cys Val Asn Asn Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser 
                85                  90                  95


Thr Ser Arg Asn Arg Leu Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln 
            100                 105                 110


Asn Ser Gly Thr Gly Leu Ser Thr Asn Leu Gln His Phe Gln Glu Glu 
        115                 120                 125


Asn Phe Arg Lys Ser Ser Pro Gln Leu Glu His Thr Gly Val Phe Leu 
    130                 135                 140


Glu Asn Val Leu Leu Ile Thr Ser His Leu 
145                 150


<210>  6590
<211>  1667
<212>  DNA
<213>  Homo sapiens

<400>  6590
gtggttccac tgcaccatct cgccaccgat tgttaagggt cctccccaac attggtcaat     60

cttgttcacc tgcttttggg aatgcatatc cgcccgaaat ctccaggaat ggaatttcaa    120

gtttggcaac tcaactctct gctgagagat acatatcttc tatcactggt gaatttctta    180

aggaagataa tagctgggag aataacacac tgtctcactt cagtagcaac gtcaaactac    240

ctcctcagat accccatttg gagttgggaa atgaccagga gcttgctgac tctgttctcc    300

atcttggatc atccctgcct aggcaaacaa aacatttttt aggaaacttg ccatctagta    360

atgggaacat tgtcttacct tcagaagaat gtgtaaccga acaatcactt ctacctaaag    420

tgggctcact ggcttcattt gcagaaggaa atgctgatga acagagcagc ggcttagaag    480

gtgcgtgcaa agtgaatctg gagttgctac tcactaatgc tgacaaaggg ttgaaagctc    540

cagagcagca tctcaagcat gttgcaggag tgctgaatgg ggaatcagta gagacttcag    600

ttcttaacta ccgggaatta agtcctcaca agaatagact cttgtcacct cttcgctgtt    660

ctgcaccaat gtcgctacat aattctctgg tgaaaccaga gagacagtcc aaatgttttg    720

agtttgggaa gctacagcct tcttcttctc agtcactgga tgttcaaaac ataactgatt    780

cttctttctc taggactact tgctttcaag gtgttaaagt tgattcactt gggaaaagat    840

ctgatgttat ttccaaagtt gaggctcggg atatcacaga aatgactaac aaggcttcca    900

aagagcctgt tggttgtgta aataatatca gttttcttgc ctcactggcc gggagcacaa    960

gcagaaatag attacagagc acacgtgggg caggcaggct tcagaactct ggaactgggc   1020

tgtctacaaa cctccagcat tttcaggaag aaaactttag gaaaagttct ccccagttag   1080

aacatacagg agtttttttg tctacccatg gtgttggaat gaatggaaat aatgcagcag   1140

cagggaaaag cgtaggagaa tgtactactc atcacctccc acctgtgaaa gcccctcttc   1200

agacaaagaa gaaaacaaca aatcattgtt ttctttgtgg aaagaaaaca ggactggcta   1260

gtagctacga atgcaggcag gttggcgagc tggagaagct cagatgcttt ctctgtgata   1320

acccagcttg gggattatgc aaaataaaat atttaaattg cctgtttata acatcattaa   1380

gatgatgttc aatagctatc ttcagttgaa cttctaattg gctgaagtaa agaacaagta   1440

gatagctcat gggtttccaa aagacaaaaa cagatccttc cttgtccttt aagttaggag   1500

gtttaaacca atctgagagt gtaccttttt cgtcttatga tgaacctgct tggattttgt   1560

ttgagtggca ccttggaaga acccctccct gaatattcta ttaaaaattt aattaaaaaa   1620

ttaaaagtta atataaaata gatgaataat atatttccaa aaaagta                 1667


<210>  6591
<211>  238
<212>  PRT
<213>  Homo sapiens

<400>  6591

Met Ser Leu His Asn Ser Leu Val Lys Pro Glu Arg Gln Ser Lys Cys 
1               5                   10                  15


Phe Glu Phe Gly Lys Leu Gln Pro Ser Ser Ser Gln Ser Leu Asp Val 
            20                  25                  30


Gln Asn Ile Thr Asp Ser Ser Phe Ser Arg Thr Thr Cys Phe Gln Gly 
        35                  40                  45


Val Lys Val Asp Ser Leu Gly Lys Arg Ser Asp Val Ile Ser Lys Val 
    50                  55                  60


Glu Ala Arg Asp Ile Thr Glu Met Thr Asn Lys Ala Ser Lys Glu Pro 
65                  70                  75                  80


Val Gly Cys Val Asn Asn Ile Ser Phe Leu Ala Ser Leu Ala Gly Ser 
                85                  90                  95


Thr Ser Arg Asn Arg Leu Gln Ser Thr Arg Gly Ala Gly Arg Leu Gln 
            100                 105                 110


Asn Ser Gly Thr Gly Leu Ser Thr Asn Leu Gln His Phe Gln Glu Glu 
        115                 120                 125


Asn Phe Arg Lys Ser Ser Pro Gln Leu Glu His Thr Gly Val Phe Leu 
    130                 135                 140


Ser Thr His Gly Val Gly Met Asn Gly Asn Asn Ala Ala Ala Gly Lys 
145                 150                 155                 160


Ser Val Gly Glu Cys Thr Thr His His Leu Pro Pro Val Lys Ala Pro 
                165                 170                 175


Leu Gln Thr Lys Lys Lys Thr Thr Asn His Cys Phe Leu Cys Gly Lys 
            180                 185                 190


Lys Thr Gly Leu Ala Ser Ser Tyr Glu Cys Arg Gln Val Gly Glu Leu 
        195                 200                 205


Glu Lys Leu Arg Cys Phe Leu Cys Asp Asn Pro Ala Trp Gly Leu Cys 
    210                 215                 220


Lys Ile Lys Tyr Leu Asn Cys Leu Phe Ile Thr Ser Leu Arg 
225                 230                 235


<210>  6592
<211>  1264
<212>  DNA
<213>  Homo sapiens

<400>  6592
aggtggtgtc acaaaggggc ggggcgcggc ggcagcggag cgttgtcggc cagtgccttc     60

cgtgaagttg ctcgccgggt cgttgggccc tgtcgacctg taggcgggcg agcgagccag    120

cggacaagac tgcgggtaca aaactcaaaa catgaacaac aatatatatt accaatcttc    180

aaacctggtt tgcctagaac tggaatacag ttgcctgcga catattttag aagaactaga    240

aaagtcaaag taatggataa cagaaaagag cctccattct tcaatgatga taacatggga    300

ccattttact acagacttca tttctgtgat accatggagc tcttcattga aacattaact    360

ggaacatgtt ttgagctgag agtttcacct tttgaaactg ttatttctgt gaaagcaaaa    420

attcgaagat tggaaggtat tcccatctgt cgacaacact taatttggaa taacatggaa    480

cttgaaaatg attattgctt gaatgattac aacatttcag aagggtgtac cttgaagcta    540

gttttggcta tgcgtggcgg acctataaat actagaagag ttcctacaga cgatccactt    600

aggaagatgg cagagtactt ggattccagt cgagttgagg tctgggagaa gacctcctgc    660

agcaaacaag ttacattttt ggtataccaa gaaggagatc aattgaattt ctttcctgca    720

gtagataggg gagatggcac tttaacaccg ttatctgact cttcaaagaa aatagatttt    780

catttgcatg tcctacggag aaaaggagaa catcgtatga gtgagaatct cctcaggatg    840

actaaaaatc tgtacttctc tcccgtgcca aatttaaaaa aattctgatt catggaaatc    900

tcatcagcct gttgtctggg ttgcacaatt atcagccttg gctgataaaa tgaaatcaga    960

cattctcatg gaaatggatt ttgcctcttt gggaatgata tggcagtggt ggttctatgt   1020

ataattcaga tacagatgag gatgaagaaa ctgagccttc ttcttctggg caacagataa   1080

ttgaaaattc aataactatg aataagatga agctgctgaa ggctaagatg aagaacatga   1140

atctcagcaa aaaggtgaag ctgttggcat ttgaccaggc ttatctctag cttacccctg   1200

cagagcactc agcaatgagg tctgttggtc attgtgaaaa aattataaag tattattcat   1260

ttca                                                                1264


<210>  6593
<211>  211
<212>  PRT
<213>  Homo sapiens

<400>  6593

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Val Pro Thr 
            100                 105                 110


Asp Asp Pro Leu Arg Lys Met Ala Glu Tyr Leu Asp Ser Ser Arg Val 
        115                 120                 125


Glu Val Trp Glu Lys Thr Ser Cys Ser Lys Gln Val Thr Phe Leu Val 
    130                 135                 140


Tyr Gln Glu Gly Asp Gln Leu Asn Phe Phe Pro Ala Val Asp Arg Gly 
145                 150                 155                 160


Asp Gly Thr Leu Thr Pro Leu Ser Asp Ser Ser Lys Lys Ile Asp Phe 
                165                 170                 175


His Leu His Val Leu Arg Arg Lys Gly Glu His Arg Met Ser Glu Asn 
            180                 185                 190


Leu Leu Arg Met Thr Lys Asn Leu Tyr Phe Ser Pro Val Pro Asn Leu 
        195                 200                 205


Lys Lys Phe 
    210


<210>  6594
<211>  2048
<212>  DNA
<213>  Homo sapiens

<400>  6594
agcggagcgt tgtcggccag tgccttccgt gaagttgctc gccgggtcgt tgggccctgt     60

cgacctgtag gcgggcgagc gagccagcgg acaagactgc gggtacaaaa ctcaaaacat    120

gaacaacaat atatattacc aatcttcaaa cctggtttgc ctagaactgg aatacagttg    180

cctgcgacat attttagaag aactagaaaa gtcaaagtaa tggataacag aaaagagcct    240

ccattcttca atgatgataa catgggacca ttttactaca gacttcattt ctgtgatacc    300

atggagctct tcattgaaac attaactgga acatgttttg agctgagagt ttcacctttt    360

gaaactgtta tttctgtgaa agcaaaaatt cgaagattgg aaggtattcc catctgtcga    420

caacacttaa tttggaataa catggaactt gaaaatgatt attgcttgaa tgattacaac    480

atttcagaag ggtgtacctt gaagctagtt ttggctatgc gtggcggacc tataaatact    540

agaagagatc ttcaaatccc aagatgatga tcgttttgca aaattccaac attgcctgtt    600

tacctggttt gtgatgtgtc tgggtttcat ggatattatc atggccccgg ttgcatcctt    660

tctcagaata taagtagttc tgaaatccag tcattcattc aacaaatacg tattgagcgt    720

ctactgaatg gtcagtgcaa tgttccaagt atggtagaca tgggagagaa agtctctgct    780

tcatgacagt gcctacaata aatgtgtaaa gagtcgatgt aactcctaat ggttgtaagt    840

gctatgcaga aaatagggta ggaagggccc tcgaaaaaga tgacattagt ggagacttga    900

ttgatgagag ggttttatta agcacaagaa gagacggcag tattcacatt ggtccctgag    960

tcaggtatgt cacatgaatt cccatgaagt ggaggagact agtcagagca tcctcttctg   1020

tggacctcat tttgaggaag tccttcagat ttatttgatc cttcactaac cagaaaaccg   1080

aaggataagt attgattcta ctcctggctt gcttccacat gtcaaattat atccctatgt   1140

ttaataattt tggttagaaa ataggattat tgccatcttt ttcttagcta tttcaagagg   1200

atttaatgag atatgctact ttggctgttg gactgctttt tataggttag agaaaaacaa   1260

agttaataat gttagggcct tttagcactc ctgataccag agacttttaa ttaattggat   1320

ttaggtaatt gtcctatgtg acatttatag taataactat aaatgtttat agtaataact   1380

atgtgatgtt tatagtaata actcttgaag tagcacaaga accctgtgtt tactgaacca   1440

ttatgttaag atagaattat atagtgttta atgccatgtg aactctattg tattacattt   1500

ttgaaagttg gttatttgtg cgtagtacta ctttaaacca aagtgtttaa tcaaaacacc   1560

tacttttctt attagaacta aaattatttt atatgtttat gaggagtgtg atacagattc   1620

tgaggtaaat atatatattt tttacttttc tttttttttt tgagacggag tcttgctctg   1680

tcaccgaggc tggagtgcag tggcatgatc tctgctcact tcaacctctg ccacctgggt   1740

tcaagtgatt ctcctgcctc agcctcccga gtagctggga ttacaggcag tggtattgag   1800

gtcaggagtt tgagaccagc ttggccaaca tggtgaaacc ccatctctac taaaaataca   1860

aaaattagct gggcatggtg gcgggctact caggaggctg agacatgaga attgcttgaa   1920

cctgggagac agacgttaca gtgagtggag actgcgccac tacagtccag tctgggtgac   1980

agaggttaca gtgagtggag actgcgccac tacagtccag tctgggtgac agagtgagac   2040

tctgtctc                                                            2048


<210>  6595
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6595

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Asp Leu Gln 
            100                 105                 110


Ile Pro Arg 
        115


<210>  6596
<211>  614
<212>  DNA
<213>  Homo sapiens

<400>  6596
ttctgttcca ttcttgcctt gtggaagcag cagaatgaac ctaggtacaa aactcaaaac     60

atgaacaaca atatatatta ccaatcttca aacctggttt gcctagaact ggaatacagt    120

tgcctgcgac atattttaga agaactagaa aagtcaaagt aatggataac agaaaagagc    180

ctccattctt caatgatgat aacatgggac cattttacta cagacttcat ttctgtgata    240

ccatggagct cttcattgaa acattaactg gaacatgttt tgagctgaga gtttcacctt    300

ttgaaactgt tatttctgtg aaagcaaaaa ttcgaagatt ggaaggtatt cccatctgtc    360

gacaacactt aatttggaat aacatggaac ttgaaaatga ttattgcttg aatgattaca    420

acatttcaga agggtgtacc ttgaagctag ttttggctat gcgtggcgga cctataaata    480

ctagaagaga tcttcaaatc ccaagatgat gatcgttttg caaaattcca acattgcctg    540

tttacctggt ttgtgatgtg tctgggtttc atggatatta tcatggcccc ggttgcatcc    600

tttctcagaa tata                                                      614


<210>  6597
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  6597

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Gly Ile Pro 
    50                  55                  60


Ile Cys Arg Gln His Leu Ile Trp Asn Asn Met Glu Leu Glu Asn Asp 
65                  70                  75                  80


Tyr Cys Leu Asn Asp Tyr Asn Ile Ser Glu Gly Cys Thr Leu Lys Leu 
                85                  90                  95


Val Leu Ala Met Arg Gly Gly Pro Ile Asn Thr Arg Arg Asp Leu Gln 
            100                 105                 110


Ile Pro Arg 
        115


<210>  6598
<211>  529
<212>  DNA
<213>  Homo sapiens

<400>  6598
agtgccttcc gtgaagttgc tcgccgggtc gttgggccct gtcgacctgt aggcgggcga     60

gcgagccagc ggacaagact gcgggtacaa aactcaaaac atgaacaaca atatatatta    120

ccaatcttca aacctggttt gcctagaact ggaatacagt tgcctgcgac atattttaga    180

agaactagaa aagtcaaagt aatggataac agaaaagagc ctccattctt caatgatgat    240

aacatgggac cattttacta cagacttcat ttctgtgata ccatggagct cttcattgaa    300

acattaactg gaacatgttt tgagctgaga gtttcacctt ttgaaactgt tatttctgtg    360

aaagcaaaaa ttcgaagatt ggaagaccca ggagatccta ctgaagtgag tggctggccg    420

agtccagtga ccacatcagc acattcagta atgactcttg aagcttttgt ctgccctaaa    480

tgatttggta ttcccatctg tcgacaacac ttaatttgga ataacatgg                529


<210>  6599
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  6599

Met Asp Asn Arg Lys Glu Pro Pro Phe Phe Asn Asp Asp Asn Met Gly 
1               5                   10                  15


Pro Phe Tyr Tyr Arg Leu His Phe Cys Asp Thr Met Glu Leu Phe Ile 
            20                  25                  30


Glu Thr Leu Thr Gly Thr Cys Phe Glu Leu Arg Val Ser Pro Phe Glu 
        35                  40                  45


Thr Val Ile Ser Val Lys Ala Lys Ile Arg Arg Leu Glu Asp Pro Gly 
    50                  55                  60


Asp Pro Thr Glu Val Ser Gly Trp Pro Ser Pro Val Thr Thr Ser Ala 
65                  70                  75                  80


His Ser Val Met Thr Leu Glu Ala Phe Val Cys Pro Lys 
                85                  90


<210>  6600
<211>  583
<212>  DNA
<213>  Homo sapiens

<400>  6600
gtgaccttgg agatacctca tcatatcaca caaagagatg cagatagatc tttgagcata     60

cctgatgaac agttacactc atttgcggtt tccaccgtgc acattacgaa gaacagaaat    120

ggaggtggga gtttaaataa ctattcctcc tccattccat cgactcccag caccagccag    180

gaggaccctc agttcagtgt tcctcccact gccaacacac ccacccccgt ttgcaagcgg    240

tccatgcgct ggtccaacct gtttacatct gagaaaggga gtgacccaga caaagagagg    300

aaagccccgg agaatcatgc tgacaccatc gggagcggca gagccatccc cattaaacag    360

ggcatgctct taaagcgaag tgggaaatgg ctgaagacat ggaaaaagaa atacgtcacc    420

ctgtgttcca atggcgtgct cacctattat tcaagcttag gtgattatat gaagaatatt    480

cataaaaaag agattgacct tcagacatct accatcaaag tcccaggaaa gtggccatcc    540

ctagccacat cggcctgcgc acccatctcc agctctaaaa gca                      583


<210>  6601
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  6601

Met Arg Trp Ser Asn Leu Phe Thr Ser Glu Lys Gly Ser Asp Pro Asp 
1               5                   10                  15


Lys Glu Arg Lys Ala Pro Glu Asn His Ala Asp Thr Ile Gly Ser Gly 
            20                  25                  30


Arg Ala Ile Pro Ile Lys Gln Gly Met Leu Leu Lys Arg Ser Gly Lys 
        35                  40                  45


Trp Leu Lys Thr Trp Lys Lys Lys Tyr Val Thr Leu Cys Ser Asn Gly 
    50                  55                  60


Val Leu Thr Tyr Tyr Ser Ser Leu Gly Asp Tyr Met Lys Asn Ile His 
65                  70                  75                  80


Lys Lys Glu Ile Asp Leu Gln Thr Ser Thr Ile Lys Val Pro Gly Lys 
                85                  90                  95


Trp Pro Ser Leu Ala Thr Ser Ala Cys Ala Pro Ile Ser Ser Ser Lys 
            100                 105                 110


<210>  6602
<211>  548
<212>  DNA
<213>  Homo sapiens

<400>  6602
agaggcgggt tgggcggggg gcgctgccgc ccaaggcccg aggcagcggc gcgggatcgg     60

ccaaagcacc ggccgccagt tcggcgggtc tggagagagg ggacctcaag cagccagtgg    120

agcaaccagc ctgggagcct tcgacgtagg cgctgtgggc gaaggaaaag gcctggcctg    180

ctgcctcttc tcttgcagca aaatccgctg ctgtgaagga gctgaaaaga agcagaccta    240

catcgtttgc agatgagctg gctgcccgca tcaaggggga tgccgtgggc cgagtggacg    300

aggagccgac aaatgaagag gataacttat tcgcaccccc caagctgacc gacgaggact    360

tctcgccatt tggctctgga ggtggcctgt tcagtggggg caaggggctc tttgatgatg    420

aggacgagga gagtgacctc ttcacggaag ccccccagga tcggcaagct ggagcctctg    480

ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cctagcagga gctgtttctg    540

tattttta                                                             548


<210>  6603
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  6603

Met Met Arg Thr Arg Arg Val Thr Ser Ser Arg Lys Pro Pro Arg Ile 
1               5                   10                  15


Gly Lys Leu Glu Pro Leu Leu Arg Arg Ser Leu His His Pro Asn Leu 
            20                  25                  30


Glu Arg Lys Ser 
        35


<210>  6604
<211>  861
<212>  DNA
<213>  Homo sapiens

<400>  6604
cgaccacggc cgctcccaca cgggctccga cgccggcacc agctcctggt cgggggtcgt     60

ccggttcatc tgcagcgaaa aaaacgagaa gagaggctga gcctgagggc ggcagggacg    120

gcggccccag cccaggccgg cccctctccg gcccgccgcc ctcaccatcc cagccgcccg    180

gctcggtggg ctccgaggct gccagcacag gccgaggacc gcagagcccc ggaagcctag    240

ccccagccaa gctgcccggg gcgtgaccgg cctcacgtga cctgatgtca cgtgacagaa    300

cccgcacgtg atccgacctg cgatgctgag gggaggaagc tgcggaagtg gactgggact    360

ggagtttggg gttctaccct aggttggggc ggaggaagct ggaggatagg ggctgacgcc    420

aggaacgctg cagaggcggg ttgggcgggg ggcgctgccg cccaaggccc gaggcagcgg    480

cgcgggatcg gccaaagcac cggccgccag ttcggcgggt ctggagagag gggacctcaa    540

gcagccagtg gagcaaccag cctgggagcc ttcgacgtag gcgctgtggg cgaaggaaaa    600

ggcctggcct gctgcctctt ctcttgcagc aaaatccgct gctgtgaagg agctgaaaag    660

aagcagacct acatcgtttg cagatgagct ggctgcccgc atcaaggggg atgccgtggg    720

ccgagtggac gaggagccga caaccttacc ctcaggagaa gcaaaacttc ggaagacact    780

caagagaaga aggaaaggag aactccttcg gacgatgaag aggataactt attcgcaccc    840

cccaagctga ccgacgagga c                                              861


<210>  6605
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  6605

Met Ser Trp Leu Pro Ala Ser Arg Gly Met Pro Trp Ala Glu Trp Thr 
1               5                   10                  15


Arg Ser Arg Gln Pro Tyr Pro Gln Glu Lys Gln Asn Phe Gly Arg His 
            20                  25                  30


Ser Arg Glu Glu Gly Lys Glu Asn Ser Phe Gly Arg 
        35                  40


<210>  6606
<211>  440
<212>  DNA
<213>  Homo sapiens

<400>  6606
tttgaaggag gagcctaaag gctaagtggc agtatctctt ctttagctta ataactagta     60

gttctaattt ggtattttat actcttagca catcacacaa gtgagtgatg aggaagagga    120

tgatgatggc tgtgaccttt ttgctgactc tgagaaggag gagaaagata ttgaggacat    180

tgaagaaaat actagaccta aaagaagcag acctacatcg tttgcagatg agctggctgc    240

ccgcatcaag ggggatgccg tgggccgagt ggacgaggag ccgacaagtg agccccagcc    300

gcgttgatgg ggagtagggg aggggtagtg cagggccctc tgctggcttc accaaaggcg    360

gatttctctt tttattagta attaccacat atatttatta gtaattgcta catataattt    420

aaattgtagt gcttattcct                                                440


<210>  6607
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  6607

Met Arg Lys Arg Met Met Met Ala Val Thr Phe Leu Leu Thr Leu Arg 
1               5                   10                  15


Arg Arg Arg Lys Ile Leu Arg Thr Leu Lys Lys Ile Leu Asp Leu Lys 
            20                  25                  30


Glu Ala Asp Leu His Arg Leu Gln Met Ser Trp Leu Pro Ala Ser Arg 
        35                  40                  45


Gly Met Pro Trp Ala Glu Trp Thr Arg Ser Arg Gln Val Ser Pro Ser 
    50                  55                  60


Arg Val Asp Gly Glu 
65


<210>  6608
<211>  4626
<212>  DNA
<213>  Homo sapiens

<400>  6608
gtcacgcccc gggcagcttg gctggggcta ggcttccggg gctctgcggt cctcggcctg     60

tgctggcagc ctcggagccc accgagccgg gcggctggga tgatgaaccg gacgaccccc    120

gaccaggagc tggtgccggc gtcggagccc gtgtgggagc ggccgtggtc ggtggaggag    180

atccgcagga gcagccagag ctggtcgctg gcggccgacg cgggcctact acagtttcta    240

caggaattct cacagcaaac tatctctagg acccatgaaa tcaagaaaca agtggacgga    300

ctaatccggg aaaccaaagc cacagattgt cgcctgcata atgtcttcaa tgacttcctt    360

atgctctcta atacccagtt catagagaat cgtgtatatg atgaagaagt ggaggagcca    420

gtactcaagg ctgaggcaga aaaaacagag caggagaaga cacgagagca gaaagaagta    480

gatctcattc ctaaagtcca ggaggctgtg aactatggct tacaagtatt ggacagtgcc    540

tttgagcaac ttgatatcaa agcaggaaac tcagactccg aggaagatga tgctaatggg    600

cgggtggaac tgatccttga accaaaggat ctatacattg atcgtccttt accatatctc    660

attgggtcaa agctgttcat ggaacaagaa gatgtaggtc ttggagagct gtccagtgaa    720

gaaggctctg taggcagtga tcgtggcagt attgtggaca ctgaggaaga gaaagaagag    780

gaggagtcag atgaagattt tgcccatcac agtgacaatg aacaaaacca gcacaccaca    840

caaatgagtg atgaggaaga ggatgatgat ggctgtgacc tttttgctga ctctgagaag    900

gaggaggaag atattgagga cattgaagaa aatactagac ctaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagga ccagtggaat   1980

attcctgctt cacagaccca cttagcatct gacagcaggt ctaaaggaga acccagggat   2040

tctgggaccc tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa   2100

gacaaagaag atgatctttt tgccattgcc aaggacagcc aaaagaagac ccagagagtg   2160

tcactcctct ttgaagacga tgttgatagc ggaggctctc tgtttggctc tcctcccaca   2220

tctgttcctc ctgcaacaaa gaaaaaagag actgtctctg aggcaccacc tttgctgttc   2280

agcgatgaag aagagaagga ggcacaactt ggagtgaagt ctgtggataa gaaggttgag   2340

agtgccaagg agtcattaaa atttgggaga actgatgtgg ctgagtcaga aaaggaagga   2400

cttttgacta gatctgctca ggaaacagtc aagcattctg atttattttc ttcatcatcc   2460

ccatgggaca aaggaaccaa gcctagaacc aaaactgttc ttagcttgtt tgatgaggaa   2520

gaggataaaa tggaagatca aaacattatc caggctccac agaaagaagt aggaaagggc   2580

tgcgatcctg atgcccaccc caagagcaca ggtgtcttcc aggatgaaga gctgcttttc   2640

agccacaagc tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa   2700

accaagctgt tagagccaag tgttgggagc ctgtttgggg atgatgaaga tgatgatctt   2760

ttcagctctg ccaagtccca gcctttggta caagagaaaa agagagtagt gaaaaaagac   2820

cactctgtta actctttcaa aaaccagaaa catcctgaat ccattcaagg tagtaaagaa   2880

aaaggcatat ggaagccgga aacacctcag gcaaatttag cgatcaaccc agcggccttg   2940

ctgcccacag cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt   3000

ccttcatctg aacacagaag gagccacggt ctggaaagtg tgcctgtcct tcccgggagt   3060

ggggaggccg gtgtgagttt tgatcttcca gctcaggcag acaccttaca cagtgcaaac   3120

aagagccgtg tcaagatgag agggaagcgt agaccgcaga cccgtgcagc taggcggctg   3180

gctgctcagg agtccagcga ggctgaggac atgagcgtcc ccagaggacc cattgcacag   3240

tgggctgatg gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga   3300

gaagacagca ctgaggaggc cctggcagct gccgctgcac cttgggaagg tggtcctgtg   3360

cctggagtgg acacaagccc ctttgcaaag tctctgggtc attccagagg ggaggctgac   3420

ctttttgatt ctggggacat tttttccacg ggcactggat ctcagtccgt ggagagaaca   3480

aaacccaagg caaagatagc agagaatcct gccaacccac cagtgggtgg taaagcaaag   3540

agccccatgt ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct   3600

aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc tggaagatga ggatgacctc   3660

tttacagatc agaaagtcaa gaagaatgag acaaaatcca gtagtcagca ggatgtcata   3720

ttaacaacac aagatatttt tgaggatgat atatttgcta cggaagcaat taaaccctct   3780

cagaaaacca gagagaagga gaaaacattg gaatctaatt tatttgatga taacattgat   3840

atctttgctg acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag   3900

tctatatttg atgatgatat ggatgacatc ttctccactg gtatccaggc taagacaacc   3960

aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa gatttgaaca caaggtgtcc   4020

aacatctttg atgatcccct gaatgccttt ggaggccagt agagcacaca gggtatccac   4080

atgttaccct gcagctacat tgttgagtta gtgatgatat tgtatatgct catggtctta   4140

actggattac aaaaagcaaa tactagaaca gctagctcat cttttaccca atgtacttag   4200

tatttttctg cactggttta atcatgctta atactacaaa acaaaaataa atatttcaca   4260

gtggttggtt tgttttgttt ttaaaccaca gtttgattta gttagccttg ctggggccat   4320

aatatgcttc agggtgtgta aaagaagaaa tctctttgtg gctttcatgg gcagggaatc   4380

tcagagatag caaatgccac ctgaccagaa gtctttgtta tatggatggg aaccctaact   4440

tagggcttgg gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca   4500

atatgggagc aggttttcac tgaattctga gggtgcctct gcatgtcctc caaggcaaag   4560

tttggcaaac tgtggccccc ccactgtcat attttgttaa taaaatttta ttggaacaca   4620

atcaca                                                              4626


<210>  6609
<211>  1320
<212>  PRT
<213>  Homo sapiens

<400>  6609

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser 
        515                 520                 525


Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser 
    530                 535                 540


Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser 
545                 550                 555                 560


Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu 
                565                 570                 575


Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr 
            580                 585                 590


Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu 
        595                 600                 605


Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp 
    610                 615                 620


Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg 
625                 630                 635                 640


Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala 
                645                 650                 655


Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp 
            660                 665                 670


Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser 
        675                 680                 685


Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser 
    690                 695                 700


Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser 
705                 710                 715                 720


Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln 
                725                 730                 735


Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser 
            740                 745                 750


Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu 
        755                 760                 765


Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser 
    770                 775                 780


Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val 
785                 790                 795                 800


Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile 
                805                 810                 815


Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala 
            820                 825                 830


His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser 
        835                 840                 845


His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly 
    850                 855                 860


Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly 
865                 870                 875                 880


Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu 
                885                 890                 895


Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser 
            900                 905                 910


Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys 
        915                 920                 925


Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro 
    930                 935                 940


Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro 
945                 950                 955                 960


Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His 
                965                 970                 975


Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val 
            980                 985                 990


Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys 
        995                 1000                1005


Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala 
    1010                1015                1020


Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val 
1025                1030                1035                1040


Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn 
                1045                1050                1055


Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu 
            1060                1065                1070


Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro 
        1075                1080                1085


Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly 
    1090                1095                1100


Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly 
1105                1110                1115                1120


Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn 
                1125                1130                1135


Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro 
            1140                1145                1150


Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys 
        1155                1160                1165


Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu 
    1170                1175                1180


Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser 
1185                1190                1195                1200


Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp 
                1205                1210                1215


Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu 
            1220                1225                1230


Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile 
        1235                1240                1245


Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val 
    1250                1255                1260


Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr 
1265                1270                1275                1280


Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala 
                1285                1290                1295


Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp 
            1300                1305                1310


Pro Leu Asn Ala Phe Gly Gly Gln 
        1315                1320


<210>  6610
<211>  4717
<212>  DNA
<213>  Homo sapiens

<400>  6610
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggat ttgttttctt ctcaaagtgc gagtaactta   1680

aaaggtgcat ctctgctgcc tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa   1740

gatgaagagg ataatctttt tgggggtaca gctgctaaga agcagacatt gtctctacaa   1800

gctcagagag aagagaaagc aaaagcctcc gagctctcca aaaagaaagc atctgccctg   1860

ttgttcagca gtgatgagga ggaccagtgg aatattcctg cttcacagac ccacttagca   1920

tctgacagca ggtctaaagg agaacccagg gattctggga ccctccagag ccaggaggcc   1980

aaggctgtga aaaagaccag tctctttgag gaagacaaag aagatgatct ttttgccatt   2040

gccaaggaca gatacatcct acctcctatt gttcccgaag ttgtctgtca agttttgtgt   2100

atggaaagta attcatacct tcatcagatc tcaaaagaag ctttacacac acaagaagaa   2160

gttgagccaa aagaagaccc agagagtgtc actcctcttt gaagacgatg ttgatagcgg   2220

aggctctctg tttggctctc ctcccacatc tgttcctcct gcaacaaaga aaaaagagac   2280

tgtctctgag gcaccacctt tgctgttcag cgatgaagaa gagaaggagg cacaacttgg   2340

agtgaagtct gtggataaga aggttgagag tgccaaggag tcattaaaat ttgggagaac   2400

tgatgtggct gagtcagaaa aggaaggact tttgactaga tctgctcagg aaacagtcaa   2460

gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc ctagaaccaa   2520

aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa acattatcca   2580

ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca agagcacagg   2640

tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca atgacccaga   2700

tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg ttgggagcct   2760

gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc ctttggtaca   2820

agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa accagaaaca   2880

tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa cacctcagga   2940

ctcatcaggt ctcgctccat ttaaaaccaa agaaccatcc actcggatcg ggaagataca   3000

agcaaattta gcgatcaacc cagcggcctt gctgcccaca gcggcttccc agatctctga   3060

agtaaagcct gttttgccag aattggcttt tccttcatct gaacacagaa ggagccacgg   3120

tctggaaagt gtgcctgtcc ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc   3180

agctcaggca gacaccttac acagtgcaaa caagagccgt gtcaagatga gagggaagcg   3240

tagaccgcag acccgtgcag ctaggcggct ggctgctcag gagtccagcg aggctgagga   3300

catgagcgtc cccagaggac ccattgcaca gtgggctgat ggcgccattt ccccaaatgg   3360

ccatcggcca cagctcagag cagccagtgg agaagacagc actgaggagg ccctggcagc   3420

tgccgctgca ccttgggaag gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa   3480

gtctctgggt cattccagag gggaggctga cctttttgat tctggggaca ttttttccac   3540

gggcactgga tctcagtccg tggagagaac aaaacccaag gcaaagatag cagagaatcc   3600

tgccaaccca ccagtgggtg gtaaagcaaa gagccccatg tttcctgctc taggcgaggc   3660

cagcagtgat gatgatctct ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc   3720

ctttcctctc ctggaagatg aggatgacct ctttacagat cagaaagtca agaagaatga   3780

gacaaaatcc agtagtcagc aggatgtcat attaacaaca caagatattt ttgaggatga   3840

tatatttgct acggaagcaa ttaaaccctc tcagaaaacc agagagaagg agaaaacatt   3900

ggaatctaat ttatttgatg ataacattga tatctttgct gacttaactg taaaaccaaa   3960

agaaaagtcc aaaaagaaag tggaagccaa gtctatattt gatgatgata tggatgacat   4020

cttctccact ggtatccagg ctaagacaac caaaccaaaa agccgatctg cacaggccgc   4080

acctgaacca agatttgaac acaaggtgtc caacatcttt gatgatcccc tgaatgcctt   4140

tggaggccag tagagcacac agggtatcca catgttaccc tgcagctaca ttgttgagtt   4200

agtgatgata ttgtatatgc tcatggtctt aactggatta caaaaagcaa atactagaac   4260

agctagctca tcttttaccc aatgtactta gtatttttct gcactggttt aatcatgctt   4320

aatactacaa aacaaaaata aatatttcac agtggttggt ttgttttgtt tttaaaccac   4380

agtttgattt agttagcctt gctggggcca taatatgctt cagggtgtgt aaaagaagaa   4440

atctctttgt ggctttcatg ggcagggaat ctcagagata gcaaatgcca cctgaccaga   4500

agtctttgtt atatggatgg gaaccctaac ttagggcttg ggcaggggaa agagaaagaa   4560

gatgagagat tatacttcat gagtcttagc aatatgggag caggttttca ctgaattctg   4620

agggtgcctc tgcatgtcct ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca   4680

tattttgtta ataaaatttt attggaacac aatcaca                            4717


<210>  6611
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6611

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6612
<211>  4654
<212>  DNA
<213>  Homo sapiens

<400>  6612
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggat ttgttttctt ctcaaagtgc gagtaactta   1680

aaaggtgcat ctctgctgcc tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa   1740

gatgaagagg ataatctttt tgggggtaca gctgctaaga agcagacatt gtctctacaa   1800

gctcagagag aagagaaagc aaaagcctcc gagctctcca aaaagaaagc atctgccctg   1860

ttgttcagca gtgatgagga ggaccagtgg aatattcctg cttcacagac ccacttagca   1920

tctgacagca ggtctaaagg agaacccagg gattctggga ccctccagag ccaggaggcc   1980

aaggctgtga aaaagaccag tctctttgag gaagacaaag aagatgatct ttttgccatt   2040

gccaaggaca gatacatcct acctcctatt gttcccgaag ttgtctgtca agttttgtgt   2100

atggaaagta attcatacct tcatcagatc tcaaaagaag ctttacacac acaagaagaa   2160

gttgagccaa aagaagaccc agagagtgtc actcctcttt gaagacgatg ttgatagcgg   2220

aggctctctg tttggctctc ctcccacatc tgttcctcct gcaacaaaga aaaaagagac   2280

tgtctctgag gcaccacctt tgctgttcag cgatgaagaa gagaaggagg cacaacttgg   2340

agtgaagtct gtggataaga aggttgagag tgccaaggag tcattaaaat ttgggagaac   2400

tgatgtggct gagtcagaaa aggaaggact tttgactaga tctgctcagg aaacagtcaa   2460

gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc ctagaaccaa   2520

aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa acattatcca   2580

ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca agagcacagg   2640

tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca atgacccaga   2700

tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg ttgggagcct   2760

gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc ctttggtaca   2820

agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa accagaaaca   2880

tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa cacctcaggc   2940

aaatttagcg atcaacccag cggccttgct gcccacagcg gcttcccaga tctctgaagt   3000

aaagcctgtt ttgccagaat tggcttttcc ttcatctgaa cacagaagga gccacggtct   3060

ggaaagtgtg cctgtccttc ccgggagtgg ggaggccggt gtgagttttg atcttccagc   3120

tcaggcagac accttacaca gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag   3180

accgcagacc cgtgcagcta ggcggctggc tgctcaggag tccagcgagg ctgaggacat   3240

gagcgtcccc agaggaccca ttgcacagtg ggctgatggc gccatttccc caaatggcca   3300

tcggccacag ctcagagcag ccagtggaga agacagcact gaggaggccc tggcagctgc   3360

cgctgcacct tgggaaggtg gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc   3420

tctgggtcat tccagagggg aggctgacct ttttgattct ggggacattt tttccacggg   3480

cactggatct cagtccgtgg agagaacaaa acccaaggca aagatagcag agaatcctgc   3540

caacccacca gtgggtggta aagcaaagag ccccatgttt cctgctctag gcgaggccag   3600

cagtgatgat gatctctttc agtctgctaa accaaaacca gcaaagaaaa caaatccctt   3660

tcctctcctg gaagatgagg atgacctctt tacagatcag aaagtcaaga agaatgagac   3720

aaaatccagt agtcagcagg atgtcatatt aacaacacaa gatatttttg aggatgatat   3780

atttgctacg gaagcaatta aaccctctca gaaaaccaga gagaaggaga aaacattgga   3840

atctaattta tttgatgata acattgatat ctttgctgac ttaactgtaa aaccaaaaga   3900

aaagtccaaa aagaaagtgg aagccaagtc tatatttgat gatgatatgg atgacatctt   3960

ctccactggt atccaggcta agacaaccaa accaaaaagc cgatctgcac aggccgcacc   4020

tgaaccaaga tttgaacaca aggtgtccaa catctttgat gatcccctga atgcctttgg   4080

aggccagtag agcacacagg gtatccacat gttaccctgc agctacattg ttgagttagt   4140

gatgatattg tatatgctca tggtcttaac tggattacaa aaagcaaata ctagaacagc   4200

tagctcatct tttacccaat gtacttagta tttttctgca ctggtttaat catgcttaat   4260

actacaaaac aaaaataaat atttcacagt ggttggtttg ttttgttttt aaaccacagt   4320

ttgatttagt tagccttgct ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc   4380

tctttgtggc tttcatgggc agggaatctc agagatagca aatgccacct gaccagaagt   4440

ctttgttata tggatgggaa ccctaactta gggcttgggc aggggaaaga gaaagaagat   4500

gagagattat acttcatgag tcttagcaat atgggagcag gttttcactg aattctgagg   4560

gtgcctctgc atgtcctcca aggcaaagtt tggcaaactg tggccccccc actgtcatat   4620

tttgttaata aaattttatt ggaacacaat caca                               4654


<210>  6613
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6613

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6614
<211>  4765
<212>  DNA
<213>  Homo sapiens

<400>  6614
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaagga tttgttttct tctcaaagtg cgagtaactt aaaaggtgca   1800

tctctgctgc ctggcaagct ccccacgtcg gtttccctgt ttgatgatga agatgaagag   1860

gataatcttt ttgggggtac agctgctaag aagcagacat tgtctctaca agctcagaga   1920

gaagagaaag caaaagcctc cgagctctcc aaaaagaaag catctgccct gttgttcagc   1980

agtgatgagg aggaccagtg gaatattcct gcttcacaga cccacttagc atctgacagc   2040

aggtctaaag gagaacccag ggattctggg accctccaga gccaggaggc caaggctgtg   2100

aaaaagacca gtctctttga ggaagacaaa gaagatgatc tttttgccat tgccaaggac   2160

agatacatcc tacctcctat tgttcccgaa gttgtctgtc aagttttgtg tatggaaagt   2220

aattcatacc ttcatcagat ctcaaaagaa gctttacaca cacaagaaga agttgagcca   2280

aaagaagacc cagagagtgt cactcctctt tgaagacgat gttgatagcg gaggctctct   2340

gtttggctct cctcccacat ctgttcctcc tgcaacaaag aaaaaagaga ctgtctctga   2400

ggcaccacct ttgctgttca gcgatgaaga agagaaggag gcacaacttg gagtgaagtc   2460

tgtggataag aaggttgaga gtgccaagga gtcattaaaa tttgggagaa ctgatgtggc   2520

tgagtcagaa aaggaaggac ttttgactag atctgctcag gaaacagtca agcattctga   2580

tttattttct tcatcatccc catgggacaa aggaaccaag cctagaacca aaactgttct   2640

tagcttgttt gatgaggaag aggataaaat ggaagatcaa aacattatcc aggctccaca   2700

gaaagaagta ggaaagggct gcgatcctga tgcccacccc aagagcacag gtgtcttcca   2760

ggatgaagag ctgcttttca gccacaagct ccaaaaggac aatgacccag atgttgacct   2820

ttttgctggc accaaaaaaa ccaagctgtt agagccaagt gttgggagcc tgtttgggga   2880

tgatgaagat gatgatcttt tcagctctgc caagtcccag cctttggtac aagagaaaaa   2940

gagagtagtg aaaaaagacc actctgttaa ctctttcaaa aaccagaaac atcctgaatc   3000

cattcaaggt agtaaagaaa aaggcatatg gaagccggaa acacctcagg caaatttagc   3060

gatcaaccca gcggccttgc tgcccacagc ggcttcccag atctctgaag taaagcctgt   3120

tttgccagaa ttggcttttc cttcatctga acacagaagg agccacggtc tggaaagtgt   3180

gcctgtcctt cccgggagtg gggaggccgg tgtgagtttt gatcttccag ctcaggcaga   3240

caccttacac agtgcaaaca agagccgtgt caagatgaga gggaagcgta gaccgcagac   3300

ccgtgcagct aggcggctgg ctgctcagga gtccagcgag gctgaggaca tgagcgtccc   3360

cagaggaccc attgcacagt gggctgatgg cgccatttcc ccaaatggcc atcggccaca   3420

gctcagagca gccagtggag aagacagcac tgaggaggcc ctggcagctg ccgctgcacc   3480

ttgggaaggt ggtcctgtgc ctggagtgga cacaagcccc tttgcaaagt ctctgggtca   3540

ttccagaggg gaggctgacc tttttgattc tggggacatt ttttccacgg gcactggatc   3600

tcagtccgtg gagagaacaa aacccaaggc aaagatagca gagaatcctg ccaacccacc   3660

agtgggtggt aaagcaaaga gccccatgtt tcctgctcta ggcgaggcca gcagtgatga   3720

tgatctcttt cagtctgcta aaccaaaacc agcaaagaaa acaaatccct ttcctctcct   3780

ggaagatgag gatgacctct ttacagatca gaaagtcaag aagaatgaga caaaatccag   3840

tagtcagcag gatgtcatat taacaacaca agatattttt gaggatgata tatttgctac   3900

ggaagcaatt aaaccctctc agaaaaccag agagaaggag aaaacattgg aatctaattt   3960

atttgatgat aacattgata tctttgctga cttaactgta aaaccaaaag aaaagtccaa   4020

aaagaaagtg gaagccaagt ctatatttga tgatgatatg gatgacatct tctccactgg   4080

tatccaggct aagacaacca aaccaaaaag ccgatctgca caggccgcac ctgaaccaag   4140

atttgaacac aaggtgtcca acatctttga tgatcccctg aatgcctttg gaggccagta   4200

gagcacacag ggtatccaca tgttaccctg cagctacatt gttgagttag tgatgatatt   4260

gtatatgctc atggtcttaa ctggattaca aaaagcaaat actagaacag ctagctcatc   4320

ttttacccaa tgtacttagt atttttctgc actggtttaa tcatgcttaa tactacaaaa   4380

caaaaataaa tatttcacag tggttggttt gttttgtttt taaaccacag tttgatttag   4440

ttagccttgc tggggccata atatgcttca gggtgtgtaa aagaagaaat ctctttgtgg   4500

ctttcatggg cagggaatct cagagatagc aaatgccacc tgaccagaag tctttgttat   4560

atggatggga accctaactt agggcttggg caggggaaag agaaagaaga tgagagatta   4620

tacttcatga gtcttagcaa tatgggagca ggttttcact gaattctgag ggtgcctctg   4680

catgtcctcc aaggcaaagt ttggcaaact gtggcccccc cactgtcata ttttgttaat   4740

aaaattttat tggaacacaa tcaca                                         4765


<210>  6615
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6615

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6616
<211>  4650
<212>  DNA
<213>  Homo sapiens

<400>  6616
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaagga tttgttttct tctcaaagtg cgagtaactt aaaaggtgca   1800

tctctgctgc ctggcaagct ccccacgtcg gtttccctgt ttgatgatga agatgaagag   1860

gataatcttt ttgggggtac agctgctaag aagcagacat tgtctctaca agctcagaga   1920

gaagagaaag caaaagcctc cgagctctcc aaaaagaaag catctgccct gttgttcagc   1980

agtgatgagg aggaccagtg gaatattcct gcttcacaga cccacttagc atctgacagc   2040

aggtctaaag gagaacccag ggattctggg accctccaga gccaggaggc caaggctgtg   2100

aaaaagacca gtctctttga ggaagacaaa gaagatgatc tttttgccat tgccaaggac   2160

agccaaaaga agacccagag agtgtcactc ctctttgaag acgatgttga tagcggaggc   2220

tctctgtttg gctctcctcc cacatctgtt cctcctgcaa caaagaaaaa agagactgtc   2280

tctgaggcac cacctttgct gttcagcgat gaagaagaga aggaggcaca acttggagtg   2340

aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat taaaatttgg gagaactgat   2400

gtggctgagt cagaaaagga aggacttttg actagatctg ctcaggaaac agtcaagcat   2460

tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag aaccaaaact   2520

gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat tatccaggct   2580

ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag cacaggtgtc   2640

ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga cccagatgtt   2700

gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg gagcctgttt   2760

ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt ggtacaagag   2820

aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca gaaacatcct   2880

gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc tcaggcaaat   2940

ttagcgatca acccagcggc cttgctgccc acagcggctt cccagatctc tgaagtaaag   3000

cctgttttgc cagaattggc ttttccttca tctgaacaca gaaggagcca cggtctggaa   3060

agtgtgcctg tccttcccgg gagtggggag gccggtgtga gttttgatct tccagctcag   3120

gcagacacct tacacagtgc aaacaagagc cgtgtcaaga tgagagggaa gcgtagaccg   3180

cagacccgtg cagctaggcg gctggctgct caggagtcca gcgaggctga ggacatgagc   3240

gtccccagag gacccattgc acagtgggct gatggcgcca tttccccaaa tggccatcgg   3300

ccacagctca gagcagccag tggagaagac agcactgagg aggccctggc agctgccgct   3360

gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa gcccctttgc aaagtctctg   3420

ggtcattcca gaggggaggc tgaccttttt gattctgggg acattttttc cacgggcact   3480

ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga tagcagagaa tcctgccaac   3540

ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg ctctaggcga ggccagcagt   3600

gatgatgatc tctttcagtc tgctaaacca aaaccagcaa agaaaacaaa tccctttcct   3660

ctcctggaag atgaggatga cctctttaca gatcagaaag tcaagaagaa tgagacaaaa   3720

tccagtagtc agcaggatgt catattaaca acacaagata tttttgagga tgatatattt   3780

gctacggaag caattaaacc ctctcagaaa accagagaga aggagaaaac attggaatct   3840

aatttatttg atgataacat tgatatcttt gctgacttaa ctgtaaaacc aaaagaaaag   3900

tccaaaaaga aagtggaagc caagtctata tttgatgatg atatggatga catcttctcc   3960

actggtatcc aggctaagac aaccaaacca aaaagccgat ctgcacaggc cgcacctgaa   4020

ccaagatttg aacacaaggt gtccaacatc tttgatgatc ccctgaatgc ctttggaggc   4080

cagtagagca cacagggtat ccacatgtta ccctgcagct acattgttga gttagtgatg   4140

atattgtata tgctcatggt cttaactgga ttacaaaaag caaatactag aacagctagc   4200

tcatctttta cccaatgtac ttagtatttt tctgcactgg tttaatcatg cttaatacta   4260

caaaacaaaa ataaatattt cacagtggtt ggtttgtttt gtttttaaac cacagtttga   4320

tttagttagc cttgctgggg ccataatatg cttcagggtg tgtaaaagaa gaaatctctt   4380

tgtggctttc atgggcaggg aatctcagag atagcaaatg ccacctgacc agaagtcttt   4440

gttatatgga tgggaaccct aacttagggc ttgggcaggg gaaagagaaa gaagatgaga   4500

gattatactt catgagtctt agcaatatgg gagcaggttt tcactgaatt ctgagggtgc   4560

ctctgcatgt cctccaaggc aaagtttggc aaactgtggc ccccccactg tcatattttg   4620

ttaataaaat tttattggaa cacaatcaca                                    4650


<210>  6617
<211>  1098
<212>  PRT
<213>  Homo sapiens

<400>  6617

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly 
                325                 330                 335


Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp 
            340                 345                 350


Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys 
        355                 360                 365


Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser 
    370                 375                 380


Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu 
385                 390                 395                 400


Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp 
                405                 410                 415


Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln 
            420                 425                 430


Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu 
        435                 440                 445


Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg 
    450                 455                 460


Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe 
465                 470                 475                 480


Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr 
                485                 490                 495


Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu 
            500                 505                 510


Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys 
        515                 520                 525


Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu 
    530                 535                 540


Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu 
545                 550                 555                 560


Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys 
                565                 570                 575


Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln 
            580                 585                 590


Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro 
        595                 600                 605


Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu 
    610                 615                 620


Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe 
625                 630                 635                 640


Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu 
                645                 650                 655


Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln 
            660                 665                 670


Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val 
        675                 680                 685


Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys 
    690                 695                 700


Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile 
705                 710                 715                 720


Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val 
                725                 730                 735


Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg 
            740                 745                 750


Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala 
        755                 760                 765


Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala 
    770                 775                 780


Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg 
785                 790                 795                 800


Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met 
                805                 810                 815


Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser 
            820                 825                 830


Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser 
        835                 840                 845


Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro 
    850                 855                 860


Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser 
865                 870                 875                 880


Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly 
                885                 890                 895


Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala 
            900                 905                 910


Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met 
        915                 920                 925


Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser 
    930                 935                 940


Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu 
945                 950                 955                 960


Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr 
                965                 970                 975


Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe 
            980                 985                 990


Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr 
        995                 1000                1005


Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile 
    1010                1015                1020


Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys 
1025                1030                1035                1040


Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe 
                1045                1050                1055


Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala 
            1060                1065                1070


Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe 
        1075                1080                1085


Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
    1090                1095


<210>  6618
<211>  4690
<212>  DNA
<213>  Homo sapiens

<400>  6618
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggaggaccag   1860

tggaatattc ctgcttcaca gacccactta gcatctgaca gcaggtctaa aggagaaccc   1920

agggattctg ggaccctcca gagccaggag gccaaggctg tgaaaaagac cagtctcttt   1980

gaggaagaca aagaagatga tctttttgcc attgccaagg acagatacat cctacctcct   2040

attgttcccg aagttgtctg tcaagttttg tgtatggaaa gtaattcata ccttcatcag   2100

atctcaaaag aagctttaca cacacaagaa gaagttgagc caaaagaaga cccagagagt   2160

gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac   2220

atctgttcct cctgcaacaa agaaaaaaga gactgtctct gaggcaccac ctttgctgtt   2280

cagcgatgaa gaagagaagg aggcacaact tggagtgaag tctgtggata agaaggttga   2340

gagtgccaag gagtcattaa aatttgggag aactgatgtg gctgagtcag aaaaggaagg   2400

acttttgact agatctgctc aggaaacagt caagcattct gatttatttt cttcatcatc   2460

cccatgggac aaaggaacca agcctagaac caaaactgtt cttagcttgt ttgatgagga   2520

agaggataaa atggaagatc aaaacattat ccaggctcca cagaaagaag taggaaaggg   2580

ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc caggatgaag agctgctttt   2640

cagccacaag ctccaaaagg acaatgaccc agatgttgac ctttttgctg gcaccaaaaa   2700

aaccaagctg ttagagccaa gtgttgggag cctgtttggg gatgatgaag atgatgatct   2760

tttcagctct gccaagtccc agcctttggt acaagagaaa aagagagtag tgaaaaaaga   2820

ccactctgtt aactctttca aaaaccagaa acatcctgaa tccattcaag gtagtaaaga   2880

aaaaggcata tggaagccgg aaacacctca ggactcatca ggtctcgctc catttaaaac   2940

caaagaacca tccactcgga tcgggaagat acaagcaaat ttagcgatca acccagcggc   3000

cttgctgccc acagcggctt cccagatctc tgaagtaaag cctgttttgc cagaattggc   3060

ttttccttca tctgaacaca gaaggagcca cggtctggaa agtgtgcctg tccttcccgg   3120

gagtggggag gccggtgtga gttttgatct tccagctcag gcagacacct tacacagtgc   3180

aaacaagagc cgtgtcaaga tgagagggaa gcgtagaccg cagacccgtg cagctaggcg   3240

gctggctgct caggagtcca gcgaggctga ggacatgagc gtccccagag gacccattgc   3300

acagtgggct gatggcgcca tttccccaaa tggccatcgg ccacagctca gagcagccag   3360

tggagaagac agcactgagg aggccctggc agctgccgct gcaccttggg aaggtggtcc   3420

tgtgcctgga gtggacacaa gcccctttgc aaagtctctg ggtcattcca gaggggaggc   3480

tgaccttttt gattctgggg acattttttc cacgggcact ggatctcagt ccgtggagag   3540

aacaaaaccc aaggcaaaga tagcagagaa tcctgccaac ccaccagtgg gtggtaaagc   3600

aaagagcccc atgtttcctg ctctaggcga ggccagcagt gatgatgatc tctttcagtc   3660

tgctaaacca aaaccagcaa agaaaacaaa tccctttcct ctcctggaag atgaggatga   3720

cctctttaca gatcagaaag tcaagaagaa tgagacaaaa tccagtagtc agcaggatgt   3780

catattaaca acacaagata tttttgagga tgatatattt gctacggaag caattaaacc   3840

ctctcagaaa accagagaga aggagaaaac attggaatct aatttatttg atgataacat   3900

tgatatcttt gctgacttaa ctgtaaaacc aaaagaaaag tccaaaaaga aagtggaagc   3960

caagtctata tttgatgatg atatggatga catcttctcc actggtatcc aggctaagac   4020

aaccaaacca aaaagccgat ctgcacaggc cgcacctgaa ccaagatttg aacacaaggt   4080

gtccaacatc tttgatgatc ccctgaatgc ctttggaggc cagtagagca cacagggtat   4140

ccacatgtta ccctgcagct acattgttga gttagtgatg atattgtata tgctcatggt   4200

cttaactgga ttacaaaaag caaatactag aacagctagc tcatctttta cccaatgtac   4260

ttagtatttt tctgcactgg tttaatcatg cttaatacta caaaacaaaa ataaatattt   4320

cacagtggtt ggtttgtttt gtttttaaac cacagtttga tttagttagc cttgctgggg   4380

ccataatatg cttcagggtg tgtaaaagaa gaaatctctt tgtggctttc atgggcaggg   4440

aatctcagag atagcaaatg ccacctgacc agaagtcttt gttatatgga tgggaaccct   4500

aacttagggc ttgggcaggg gaaagagaaa gaagatgaga gattatactt catgagtctt   4560

agcaatatgg gagcaggttt tcactgaatt ctgagggtgc ctctgcatgt cctccaaggc   4620

aaagtttggc aaactgtggc ccccccactg tcatattttg ttaataaaat tttattggaa   4680

cacaatcaca                                                          4690


<210>  6619
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6619

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6620
<211>  4477
<212>  DNA
<213>  Homo sapiens

<400>  6620
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagc caaaagaaga cccagagagt   2100

gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac   2160

atctgttcct cctgcaacaa aggaaggact tttgactaga tctgctcagg aaacagtcaa   2220

gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc ctagaaccaa   2280

aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa acattatcca   2340

ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca agagcacagg   2400

tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca atgacccaga   2460

tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg ttgggagcct   2520

gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc ctttggtaca   2580

agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa accagaaaca   2640

tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa cacctcagga   2700

ctcatcaggt ctcgctccat ttaaaaccaa agaaccatcc actcggatcg ggaagataca   2760

agcaaattta gcgatcaacc cagcggcctt gctgcccaca gcggcttccc agatctctga   2820

agtaaagcct gttttgccag aattggcttt tccttcatct gaacacagaa ggagccacgg   2880

tctggaaagt gtgcctgtcc ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc   2940

agctcaggca gacaccttac acagtgcaaa caagagccgt gtcaagatga gagggaagcg   3000

tagaccgcag acccgtgcag ctaggcggct ggctgctcag gagtccagcg aggctgagga   3060

catgagcgtc cccagaggac ccattgcaca gtgggctgat ggcgccattt ccccaaatgg   3120

ccatcggcca cagctcagag cagccagtgg agaagacagc actgaggagg ccctggcagc   3180

tgccgctgca ccttgggaag gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa   3240

gtctctgggt cattccagag gggaggctga cctttttgat tctggggaca ttttttccac   3300

gggcactgga tctcagtccg tggagagaac aaaacccaag gcaaagatag cagagaatcc   3360

tgccaaccca ccagtgggtg gtaaagcaaa gagccccatg tttcctgctc taggcgaggc   3420

cagcagtgat gatgatctct ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc   3480

ctttcctctc ctggaagatg aggatgacct ctttacagat cagaaagtca agaagaatga   3540

gacaaaatcc agtagtcagc aggatgtcat attaacaaca caagatattt ttgaggatga   3600

tatatttgct acggaagcaa ttaaaccctc tcagaaaacc agagagaagg agaaaacatt   3660

ggaatctaat ttatttgatg ataacattga tatctttgct gacttaactg taaaaccaaa   3720

agaaaagtcc aaaaagaaag tggaagccaa gtctatattt gatgatgata tggatgacat   3780

cttctccact ggtatccagg ctaagacaac caaaccaaaa agccgatctg cacaggccgc   3840

acctgaacca agatttgaac acaaggtgtc caacatcttt gatgatcccc tgaatgcctt   3900

tggaggccag tagagcacac agggtatcca catgttaccc tgcagctaca ttgttgagtt   3960

agtgatgata ttgtatatgc tcatggtctt aactggatta caaaaagcaa atactagaac   4020

agctagctca tcttttaccc aatgtactta gtatttttct gcactggttt aatcatgctt   4080

aatactacaa aacaaaaata aatatttcac agtggttggt ttgttttgtt tttaaaccac   4140

agtttgattt agttagcctt gctggggcca taatatgctt cagggtgtgt aaaagaagaa   4200

atctctttgt ggctttcatg ggcagggaat ctcagagata gcaaatgcca cctgaccaga   4260

agtctttgtt atatggatgg gaaccctaac ttagggcttg ggcaggggaa agagaaagaa   4320

gatgagagat tatacttcat gagtcttagc aatatgggag caggttttca ctgaattctg   4380

agggtgcctc tgcatgtcct ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca   4440

tattttgtta ataaaatttt attggaacac aatcaca                            4477


<210>  6621
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6621

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6622
<211>  4366
<212>  DNA
<213>  Homo sapiens

<400>  6622
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagcc aaaagaagac   1980

ccagagagtg tcactcctct ttgaagacga tgttgatagc ggaggctctc tgtttggctc   2040

tcctcccaca tctgttcctc ctgcaacaaa ggaaggactt ttgactagat ctgctcagga   2100

aacagtcaag cattctgatt tattttcttc atcatcccca tgggacaaag gaaccaagcc   2160

tagaaccaaa actgttctta gcttgtttga tgaggaagag gataaaatgg aagatcaaaa   2220

cattatccag gctccacaga aagaagtagg aaagggctgc gatcctgatg cccaccccaa   2280

gagcacaggt gtcttccagg atgaagagct gcttttcagc cacaagctcc aaaaggacaa   2340

tgacccagat gttgaccttt ttgctggcac caaaaaaacc aagctgttag agccaagtgt   2400

tgggagcctg tttggggatg atgaagatga tgatcttttc agctctgcca agtcccagcc   2460

tttggtacaa gagaaaaaga gagtagtgaa aaaagaccac tctgttaact ctttcaaaaa   2520

ccagaaacat cctgaatcca ttcaaggtag taaagaaaaa ggcatatgga agccggaaac   2580

acctcaggac tcatcaggtc tcgctccatt taaaaccaaa gaaccatcca ctcggatcgg   2640

gaagatacaa gcaaatttag cgatcaaccc agcggccttg ctgcccacag cggcttccca   2700

gatctctgaa gtaaagcctg ttttgccaga attggctttt ccttcatctg aacacagaag   2760

gagccacggt ctggaaagtg tgcctgtcct tcccgggagt ggggaggccg gtgtgagttt   2820

tgatcttcca gctcaggcag acaccttaca cagtgcaaac aagagccgtg tcaagatgag   2880

agggaagcgt agaccgcaga cccgtgcagc taggcggctg gctgctcagg agtccagcga   2940

ggctgaggac atgagcgtcc ccagaggacc cattgcacag tgggctgatg gcgccatttc   3000

cccaaatggc catcggccac agctcagagc agccagtgga gaagacagca ctgaggaggc   3060

cctggcagct gccgctgcac cttgggaagg tggtcctgtg cctggagtgg acacaagccc   3120

ctttgcaaag tctctgggtc attccagagg ggaggctgac ctttttgatt ctggggacat   3180

tttttccacg ggcactggat ctcagtccgt ggagagaaca aaacccaagg caaagatagc   3240

agagaatcct gccaacccac cagtgggtgg taaagcaaag agccccatgt ttcctgctct   3300

aggcgaggcc agcagtgatg atgatctctt tcagtctgct aaaccaaaac cagcaaagaa   3360

aacaaatccc tttcctctcc tggaagatga ggatgacctc tttacagatc agaaagtcaa   3420

gaagaatgag acaaaatcca gtagtcagca ggatgtcata ttaacaacac aagatatttt   3480

tgaggatgat atatttgcta cggaagcaat taaaccctct cagaaaacca gagagaagga   3540

gaaaacattg gaatctaatt tatttgatga taacattgat atctttgctg acttaactgt   3600

aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag tctatatttg atgatgatat   3660

ggatgacatc ttctccactg gtatccaggc taagacaacc aaaccaaaaa gccgatctgc   3720

acaggccgca cctgaaccaa gatttgaaca caaggtgtcc aacatctttg atgatcccct   3780

gaatgccttt ggaggccagt agagcacaca gggtatccac atgttaccct gcagctacat   3840

tgttgagtta gtgatgatat tgtatatgct catggtctta actggattac aaaaagcaaa   3900

tactagaaca gctagctcat cttttaccca atgtacttag tatttttctg cactggttta   3960

atcatgctta atactacaaa acaaaaataa atatttcaca gtggttggtt tgttttgttt   4020

ttaaaccaca gtttgattta gttagccttg ctggggccat aatatgcttc agggtgtgta   4080

aaagaagaaa tctctttgtg gctttcatgg gcagggaatc tcagagatag caaatgccac   4140

ctgaccagaa gtctttgtta tatggatggg aaccctaact tagggcttgg gcaggggaaa   4200

gagaaagaag atgagagatt atacttcatg agtcttagca atatgggagc aggttttcac   4260

tgaattctga gggtgcctct gcatgtcctc caaggcaaag tttggcaaac tgtggccccc   4320

ccactgtcat attttgttaa taaaatttta ttggaacaca atcaca                  4366


<210>  6623
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6623

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6624
<211>  4651
<212>  DNA
<213>  Homo sapiens

<400>  6624
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggatttg ttttcttctc aaagtgcgag taacttaaaa   1680

ggtgcatctc tgctgcctgg caagctcccc acgtcggttt ccctgtttga tgatgaagat   1740

gaagaggata atctttttgg gggtacagct gctaagaagc agacattgtc tctacaagct   1800

cagagagaag agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg   1860

ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca cttagcatct   1920

gacagcaggt ctaaaggaga acccagggat tctgggaccc tccagagcca ggaggccaag   1980

gctgtgaaaa agaccagtct ctttgaggaa gacaaagaag atgatctttt tgccattgcc   2040

aaggacagat acatcctacc tcctattgtt cccgaagttg tctgtcaagt tttgtgtatg   2100

gaaagtaatt cataccttca tcagatctca aaagaagctt tacacacaca agaagaagtt   2160

gagccaaaag aagacccaga gagtgtcact cctctttgaa gacgatgttg atagcggagg   2220

ctctctgttt ggctctcctc ccacatctgt tcctcctgca acaaagaaaa aagagactgt   2280

ctctgaggca ccacctttgc tgttcagcga tgaagaagag aaggaggcac aacttggagt   2340

gaagtctgtg gataagaagg ttgagagtgc caaggagtca ttaaaatttg ggagaactga   2400

tgtggctgag tcagaaaagg aaggactttt gactagatct gctcaggaaa cagtcaagca   2460

ttctgattta ttttcttcat catccccatg ggacaaagga accaagccta gaaccaaaac   2520

tgttcttagc ttgtttgatg aggaagagga taaaatggaa gatcaaaaca ttatccaggc   2580

tccacagaaa gaagtaggaa agggctgcga tcctgatgcc caccccaaga gcacaggtgt   2640

cttccaggat gaagagctgc ttttcagcca caagctccaa aaggacaatg acccagatgt   2700

tgaccttttt gctggcacca aaaaaaccaa gctgttagag ccaagtgttg ggagcctgtt   2760

tggggatgat gaagatgatg atcttttcag ctctgccaag tcccagcctt tggtacaaga   2820

gaaaaagaga gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc agaaacatcc   2880

tgaatccatt caaggtagta aagaaaaagg catatggaag ccggaaacac ctcaggcaaa   2940

tttagcgatc aacccagcgg ccttgctgcc cacagcggct tcccagatct ctgaagtaaa   3000

gcctgttttg ccagaattgg cttttccttc atctgaacac agaaggagcc acggtctgga   3060

aagtgtgcct gtccttcccg ggagtgggga ggccggtgtg agttttgatc ttccagctca   3120

ggcagacacc ttacacagtg caaacaagag ccgtgtcaag atgagaggga agcgtagacc   3180

gcagacccgt gcagctaggc ggctggctgc tcaggagtcc agcgaggctg aggacatgag   3240

cgtccccaga ggacccattg cacagtgggc tgatggcgcc atttccccaa atggccatcg   3300

gccacagctc agagcagcca gtggagaaga cagcactgag gaggccctgg cagctgccgc   3360

tgcaccttgg gaaggtggtc ctgtgcctgg agtggacaca agcccctttg caaagtctct   3420

gggtcattcc agaggggagg ctgacctttt tgattctggg gacatttttt ccacgggcac   3480

tggatctcag tccgtggaga gaacaaaacc caaggcaaag atagcagaga atcctgccaa   3540

cccaccagtg ggtggtaaag caaagagccc catgtttcct gctctaggcg aggccagcag   3600

tgatgatgat ctctttcagt ctgctaaacc aaaaccagca aagaaaacaa atccctttcc   3660

tctcctggaa gatgaggatg acctctttac agatcagaaa gtcaagaaga atgagacaaa   3720

atccagtagt cagcaggatg tcatattaac aacacaagat atttttgagg atgatatatt   3780

tgctacggaa gcaattaaac cctctcagaa aaccagagag aaggagaaaa cattggaatc   3840

taatttattt gatgataaca ttgatatctt tgctgactta actgtaaaac caaaagaaaa   3900

gtccaaaaag aaagtggaag ccaagtctat atttgatgat gatatggatg acatcttctc   3960

cactggtatc caggctaaga caaccaaacc aaaaagccga tctgcacagg ccgcacctga   4020

accaagattt gaacacaagg tgtccaacat ctttgatgat cccctgaatg cctttggagg   4080

ccagtagagc acacagggta tccacatgtt accctgcagc tacattgttg agttagtgat   4140

gatattgtat atgctcatgg tcttaactgg attacaaaaa gcaaatacta gaacagctag   4200

ctcatctttt acccaatgta cttagtattt ttctgcactg gtttaatcat gcttaatact   4260

acaaaacaaa aataaatatt tcacagtggt tggtttgttt tgtttttaaa ccacagtttg   4320

atttagttag ccttgctggg gccataatat gcttcagggt gtgtaaaaga agaaatctct   4380

ttgtggcttt catgggcagg gaatctcaga gatagcaaat gccacctgac cagaagtctt   4440

tgttatatgg atgggaaccc taacttaggg cttgggcagg ggaaagagaa agaagatgag   4500

agattatact tcatgagtct tagcaatatg ggagcaggtt ttcactgaat tctgagggtg   4560

cctctgcatg tcctccaagg caaagtttgg caaactgtgg cccccccact gtcatatttt   4620

gttaataaaa ttttattgga acacaatcac a                                  4651


<210>  6625
<211>  700
<212>  PRT
<213>  Homo sapiens

<400>  6625

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys 
        515                 520                 525


Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe 
    530                 535                 540


Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys 
545                 550                 555                 560


Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala 
                565                 570                 575


Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp 
            580                 585                 590


Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser 
        595                 600                 605


Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser 
    610                 615                 620


Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys 
625                 630                 635                 640


Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Arg Tyr Ile Leu Pro Pro 
                645                 650                 655


Ile Val Pro Glu Val Val Cys Gln Val Leu Cys Met Glu Ser Asn Ser 
            660                 665                 670


Tyr Leu His Gln Ile Ser Lys Glu Ala Leu His Thr Gln Glu Glu Val 
        675                 680                 685


Glu Pro Lys Glu Asp Pro Glu Ser Val Thr Pro Leu 
    690                 695                 700


<210>  6626
<211>  4599
<212>  DNA
<213>  Homo sapiens

<400>  6626
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggatttg ttttcttctc aaagtgcgag taacttaaaa   1680

ggtgcatctc tgctgcctgg caagctcccc acgtcggttt ccctgtttga tgatgaagat   1740

gaagaggata atctttttgg gggtacagct gctaagaagc agacattgtc tctacaagct   1800

cagagagaag agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg   1860

ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca cttagcatct   1920

gacagcaggt ctaaaggaga acccagggat tctgggaccc tccagagcca ggaggccaag   1980

gctgtgaaaa agaccagtct ctttgaggaa gacaaagaag atgatctttt tgccattgcc   2040

aaggacagcc aaaagaagac ccagagagtg tcactcctct ttgaagacga tgttgatagc   2100

ggaggctctc tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag   2160

actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga ggcacaactt   2220

ggagtgaagt ctgtggataa gaaggttgag agtgccaagg agtcattaaa atttgggaga   2280

actgatgtgg ctgagtcaga aaaggaagga cttttgacta gatctgctca ggaaacagtc   2340

aagcattctg atttattttc ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc   2400

aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc   2460

caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc caagagcaca   2520

ggtgtcttcc aggatgaaga gctgcttttc agccacaagc tccaaaagga caatgaccca   2580

gatgttgacc tttttgctgg caccaaaaaa accaagctgt tagagccaag tgttgggagc   2640

ctgtttgggg atgatgaaga tgatgatctt ttcagctctg ccaagtccca gcctttggta   2700

caagagaaaa agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa   2760

catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga aacacctcag   2820

gactcatcag gtctcgctcc atttaaaacc aaagaaccat ccactcggat cgggaagata   2880

caagcaaatt tagcgatcaa cccagcggcc ttgctgccca cagcggcttc ccagatctct   2940

gaagtaaagc ctgttttgcc agaattggct tttccttcat ctgaacacag aaggagccac   3000

ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg ccggtgtgag ttttgatctt   3060

ccagctcagg cagacacctt acacagtgca aacaagagcc gtgtcaagat gagagggaag   3120

cgtagaccgc agacccgtgc agctaggcgg ctggctgctc aggagtccag cgaggctgag   3180

gacatgagcg tccccagagg acccattgca cagtgggctg atggcgccat ttccccaaat   3240

ggccatcggc cacagctcag agcagccagt ggagaagaca gcactgagga ggccctggca   3300

gctgccgctg caccttggga aggtggtcct gtgcctggag tggacacaag cccctttgca   3360

aagtctctgg gtcattccag aggggaggct gacctttttg attctgggga cattttttcc   3420

acgggcactg gatctcagtc cgtggagaga acaaaaccca aggcaaagat agcagagaat   3480

cctgccaacc caccagtggg tggtaaagca aagagcccca tgtttcctgc tctaggcgag   3540

gccagcagtg atgatgatct ctttcagtct gctaaaccaa aaccagcaaa gaaaacaaat   3600

ccctttcctc tcctggaaga tgaggatgac ctctttacag atcagaaagt caagaagaat   3660

gagacaaaat ccagtagtca gcaggatgtc atattaacaa cacaagatat ttttgaggat   3720

gatatatttg ctacggaagc aattaaaccc tctcagaaaa ccagagagaa ggagaaaaca   3780

ttggaatcta atttatttga tgataacatt gatatctttg ctgacttaac tgtaaaacca   3840

aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat ttgatgatga tatggatgac   3900

atcttctcca ctggtatcca ggctaagaca accaaaccaa aaagccgatc tgcacaggcc   3960

gcacctgaac caagatttga acacaaggtg tccaacatct ttgatgatcc cctgaatgcc   4020

tttggaggcc agtagagcac acagggtatc cacatgttac cctgcagcta cattgttgag   4080

ttagtgatga tattgtatat gctcatggtc ttaactggat tacaaaaagc aaatactaga   4140

acagctagct catcttttac ccaatgtact tagtattttt ctgcactggt ttaatcatgc   4200

ttaatactac aaaacaaaaa taaatatttc acagtggttg gtttgttttg tttttaaacc   4260

acagtttgat ttagttagcc ttgctggggc cataatatgc ttcagggtgt gtaaaagaag   4320

aaatctcttt gtggctttca tgggcaggga atctcagaga tagcaaatgc cacctgacca   4380

gaagtctttg ttatatggat gggaacccta acttagggct tgggcagggg aaagagaaag   4440

aagatgagag attatacttc atgagtctta gcaatatggg agcaggtttt cactgaattc   4500

tgagggtgcc tctgcatgtc ctccaaggca aagtttggca aactgtggcc cccccactgt   4560

catattttgt taataaaatt ttattggaac acaatcaca                          4599


<210>  6627
<211>  1312
<212>  PRT
<213>  Homo sapiens

<400>  6627

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys 
        515                 520                 525


Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe 
    530                 535                 540


Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys 
545                 550                 555                 560


Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala 
                565                 570                 575


Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp 
            580                 585                 590


Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser 
        595                 600                 605


Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser 
    610                 615                 620


Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys 
625                 630                 635                 640


Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln 
                645                 650                 655


Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu 
            660                 665                 670


Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu 
        675                 680                 685


Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys 
    690                 695                 700


Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala 
705                 710                 715                 720


Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys 
                725                 730                 735


Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp 
            740                 745                 750


Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr 
        755                 760                 765


Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp 
    770                 775                 780


Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp 
785                 790                 795                 800


Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu 
                805                 810                 815


Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu 
            820                 825                 830


Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser 
        835                 840                 845


Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser 
    850                 855                 860


Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser 
865                 870                 875                 880


Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser 
                885                 890                 895


Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly 
            900                 905                 910


Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile 
        915                 920                 925


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
    930                 935                 940


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
945                 950                 955                 960


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
                965                 970                 975


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
            980                 985                 990


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
        995                 1000                1005


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
    1010                1015                1020


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
1025                1030                1035                1040


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
                1045                1050                1055


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
            1060                1065                1070


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
        1075                1080                1085


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
    1090                1095                1100


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
1105                1110                1115                1120


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
                1125                1130                1135


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
            1140                1145                1150


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
        1155                1160                1165


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
    1170                1175                1180


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
1185                1190                1195                1200


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
                1205                1210                1215


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
            1220                1225                1230


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
        1235                1240                1245


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
    1250                1255                1260


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
1265                1270                1275                1280


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
                1285                1290                1295


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            1300                1305                1310


<210>  6628
<211>  4303
<212>  DNA
<213>  Homo sapiens

<400>  6628
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagcc aaaagaagac   1980

ccagagagtg tcactcctct ttgaagacga tgttgatagc ggaggctctc tgtttggctc   2040

tcctcccaca tctgttcctc ctgcaacaaa ggaaggactt ttgactagat ctgctcagga   2100

aacagtcaag cattctgatt tattttcttc atcatcccca tgggacaaag gaaccaagcc   2160

tagaaccaaa actgttctta gcttgtttga tgaggaagag gataaaatgg aagatcaaaa   2220

cattatccag gctccacaga aagaagtagg aaagggctgc gatcctgatg cccaccccaa   2280

gagcacaggt gtcttccagg atgaagagct gcttttcagc cacaagctcc aaaaggacaa   2340

tgacccagat gttgaccttt ttgctggcac caaaaaaacc aagctgttag agccaagtgt   2400

tgggagcctg tttggggatg atgaagatga tgatcttttc agctctgcca agtcccagcc   2460

tttggtacaa gagaaaaaga gagtagtgaa aaaagaccac tctgttaact ctttcaaaaa   2520

ccagaaacat cctgaatcca ttcaaggtag taaagaaaaa ggcatatgga agccggaaac   2580

acctcaggca aatttagcga tcaacccagc ggccttgctg cccacagcgg cttcccagat   2640

ctctgaagta aagcctgttt tgccagaatt ggcttttcct tcatctgaac acagaaggag   2700

ccacggtctg gaaagtgtgc ctgtccttcc cgggagtggg gaggccggtg tgagttttga   2760

tcttccagct caggcagaca ccttacacag tgcaaacaag agccgtgtca agatgagagg   2820

gaagcgtaga ccgcagaccc gtgcagctag gcggctggct gctcaggagt ccagcgaggc   2880

tgaggacatg agcgtcccca gaggacccat tgcacagtgg gctgatggcg ccatttcccc   2940

aaatggccat cggccacagc tcagagcagc cagtggagaa gacagcactg aggaggccct   3000

ggcagctgcc gctgcacctt gggaaggtgg tcctgtgcct ggagtggaca caagcccctt   3060

tgcaaagtct ctgggtcatt ccagagggga ggctgacctt tttgattctg gggacatttt   3120

ttccacgggc actggatctc agtccgtgga gagaacaaaa cccaaggcaa agatagcaga   3180

gaatcctgcc aacccaccag tgggtggtaa agcaaagagc cccatgtttc ctgctctagg   3240

cgaggccagc agtgatgatg atctctttca gtctgctaaa ccaaaaccag caaagaaaac   3300

aaatcccttt cctctcctgg aagatgagga tgacctcttt acagatcaga aagtcaagaa   3360

gaatgagaca aaatccagta gtcagcagga tgtcatatta acaacacaag atatttttga   3420

ggatgatata tttgctacgg aagcaattaa accctctcag aaaaccagag agaaggagaa   3480

aacattggaa tctaatttat ttgatgataa cattgatatc tttgctgact taactgtaaa   3540

accaaaagaa aagtccaaaa agaaagtgga agccaagtct atatttgatg atgatatgga   3600

tgacatcttc tccactggta tccaggctaa gacaaccaaa ccaaaaagcc gatctgcaca   3660

ggccgcacct gaaccaagat ttgaacacaa ggtgtccaac atctttgatg atcccctgaa   3720

tgcctttgga ggccagtaga gcacacaggg tatccacatg ttaccctgca gctacattgt   3780

tgagttagtg atgatattgt atatgctcat ggtcttaact ggattacaaa aagcaaatac   3840

tagaacagct agctcatctt ttacccaatg tacttagtat ttttctgcac tggtttaatc   3900

atgcttaata ctacaaaaca aaaataaata tttcacagtg gttggtttgt tttgttttta   3960

aaccacagtt tgatttagtt agccttgctg gggccataat atgcttcagg gtgtgtaaaa   4020

gaagaaatct ctttgtggct ttcatgggca gggaatctca gagatagcaa atgccacctg   4080

accagaagtc tttgttatat ggatgggaac cctaacttag ggcttgggca ggggaaagag   4140

aaagaagatg agagattata cttcatgagt cttagcaata tgggagcagg ttttcactga   4200

attctgaggg tgcctctgca tgtcctccaa ggcaaagttt ggcaaactgt ggccccccca   4260

ctgtcatatt ttgttaataa aattttattg gaacacaatc aca                     4303


<210>  6629
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6629

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6630
<211>  4804
<212>  DNA
<213>  Homo sapiens

<400>  6630
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagga ccagtggaat   1980

attcctgctt cacagaccca cttagcatct gacagcaggt ctaaaggaga acccagggat   2040

tctgggaccc tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa   2100

gacaaagaag atgatctttt tgccattgcc aaggacagat acatcctacc tcctattgtt   2160

cccgaagttg tctgtcaagt tttgtgtatg gaaagtaatt cataccttca tcagatctca   2220

aaagaagctt tacacacaca agaagaagtt gagccaaaag aagacccaga gagtgtcact   2280

cctctttgaa gacgatgttg atagcggagg ctctctgttt ggctctcctc ccacatctgt   2340

tcctcctgca acaaagaaaa aagagactgt ctctgaggca ccacctttgc tgttcagcga   2400

tgaagaagag aaggaggcac aacttggagt gaagtctgtg gataagaagg ttgagagtgc   2460

caaggagtca ttaaaatttg ggagaactga tgtggctgag tcagaaaagg aaggactttt   2520

gactagatct gctcaggaaa cagtcaagca ttctgattta ttttcttcat catccccatg   2580

ggacaaagga accaagccta gaaccaaaac tgttcttagc ttgtttgatg aggaagagga   2640

taaaatggaa gatcaaaaca ttatccaggc tccacagaaa gaagtaggaa agggctgcga   2700

tcctgatgcc caccccaaga gcacaggtgt cttccaggat gaagagctgc ttttcagcca   2760

caagctccaa aaggacaatg acccagatgt tgaccttttt gctggcacca aaaaaaccaa   2820

gctgttagag ccaagtgttg ggagcctgtt tggggatgat gaagatgatg atcttttcag   2880

ctctgccaag tcccagcctt tggtacaaga gaaaaagaga gtagtgaaaa aagaccactc   2940

tgttaactct ttcaaaaacc agaaacatcc tgaatccatt caaggtagta aagaaaaagg   3000

catatggaag ccggaaacac ctcaggactc atcaggtctc gctccattta aaaccaaaga   3060

accatccact cggatcggga agatacaagc aaatttagcg atcaacccag cggccttgct   3120

gcccacagcg gcttcccaga tctctgaagt aaagcctgtt ttgccagaat tggcttttcc   3180

ttcatctgaa cacagaagga gccacggtct ggaaagtgtg cctgtccttc ccgggagtgg   3240

ggaggccggt gtgagttttg atcttccagc tcaggcagac accttacaca gtgcaaacaa   3300

gagccgtgtc aagatgagag ggaagcgtag accgcagacc cgtgcagcta ggcggctggc   3360

tgctcaggag tccagcgagg ctgaggacat gagcgtcccc agaggaccca ttgcacagtg   3420

ggctgatggc gccatttccc caaatggcca tcggccacag ctcagagcag ccagtggaga   3480

agacagcact gaggaggccc tggcagctgc cgctgcacct tgggaaggtg gtcctgtgcc   3540

tggagtggac acaagcccct ttgcaaagtc tctgggtcat tccagagggg aggctgacct   3600

ttttgattct ggggacattt tttccacggg cactggatct cagtccgtgg agagaacaaa   3660

acccaaggca aagatagcag agaatcctgc caacccacca gtgggtggta aagcaaagag   3720

ccccatgttt cctgctctag gcgaggccag cagtgatgat gatctctttc agtctgctaa   3780

accaaaacca gcaaagaaaa caaatccctt tcctctcctg gaagatgagg atgacctctt   3840

tacagatcag aaagtcaaga agaatgagac aaaatccagt agtcagcagg atgtcatatt   3900

aacaacacaa gatatttttg aggatgatat atttgctacg gaagcaatta aaccctctca   3960

gaaaaccaga gagaaggaga aaacattgga atctaattta tttgatgata acattgatat   4020

ctttgctgac ttaactgtaa aaccaaaaga aaagtccaaa aagaaagtgg aagccaagtc   4080

tatatttgat gatgatatgg atgacatctt ctccactggt atccaggcta agacaaccaa   4140

accaaaaagc cgatctgcac aggccgcacc tgaaccaaga tttgaacaca aggtgtccaa   4200

catctttgat gatcccctga atgcctttgg aggccagtag agcacacagg gtatccacat   4260

gttaccctgc agctacattg ttgagttagt gatgatattg tatatgctca tggtcttaac   4320

tggattacaa aaagcaaata ctagaacagc tagctcatct tttacccaat gtacttagta   4380

tttttctgca ctggtttaat catgcttaat actacaaaac aaaaataaat atttcacagt   4440

ggttggtttg ttttgttttt aaaccacagt ttgatttagt tagccttgct ggggccataa   4500

tatgcttcag ggtgtgtaaa agaagaaatc tctttgtggc tttcatgggc agggaatctc   4560

agagatagca aatgccacct gaccagaagt ctttgttata tggatgggaa ccctaactta   4620

gggcttgggc aggggaaaga gaaagaagat gagagattat acttcatgag tcttagcaat   4680

atgggagcag gttttcactg aattctgagg gtgcctctgc atgtcctcca aggcaaagtt   4740

tggcaaactg tggccccccc actgtcatat tttgttaata aaattttatt ggaacacaat   4800

caca                                                                4804


<210>  6631
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6631

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6632
<211>  4539
<212>  DNA
<213>  Homo sapiens

<400>  6632
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggat ttgttttctt ctcaaagtgc gagtaactta   1680

aaaggtgcat ctctgctgcc tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa   1740

gatgaagagg ataatctttt tgggggtaca gctgctaaga agcagacatt gtctctacaa   1800

gctcagagag aagagaaagc aaaagcctcc gagctctcca aaaagaaagc atctgccctg   1860

ttgttcagca gtgatgagga ggaccagtgg aatattcctg cttcacagac ccacttagca   1920

tctgacagca ggtctaaagg agaacccagg gattctggga ccctccagag ccaggaggcc   1980

aaggctgtga aaaagaccag tctctttgag gaagacaaag aagatgatct ttttgccatt   2040

gccaaggaca gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat   2100

agcggaggct ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa   2160

gagactgtct ctgaggcacc acctttgctg ttcagcgatg aagaagagaa ggaggcacaa   2220

cttggagtga agtctgtgga taagaaggtt gagagtgcca aggagtcatt aaaatttggg   2280

agaactgatg tggctgagtc agaaaaggaa ggacttttga ctagatctgc tcaggaaaca   2340

gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac caagcctaga   2400

accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga tcaaaacatt   2460

atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca ccccaagagc   2520

acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa ggacaatgac   2580

ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg   2640

agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc ccagcctttg   2700

gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt caaaaaccag   2760

aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct   2820

caggcaaatt tagcgatcaa cccagcggcc ttgctgccca cagcggcttc ccagatctct   2880

gaagtaaagc ctgttttgcc agaattggct tttccttcat ctgaacacag aaggagccac   2940

ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg ccggtgtgag ttttgatctt   3000

ccagctcagg cagacacctt acacagtgca aacaagagcc gtgtcaagat gagagggaag   3060

cgtagaccgc agacccgtgc agctaggcgg ctggctgctc aggagtccag cgaggctgag   3120

gacatgagcg tccccagagg acccattgca cagtgggctg atggcgccat ttccccaaat   3180

ggccatcggc cacagctcag agcagccagt ggagaagaca gcactgagga ggccctggca   3240

gctgccgctg caccttggga aggtggtcct gtgcctggag tggacacaag cccctttgca   3300

aagtctctgg gtcattccag aggggaggct gacctttttg attctgggga cattttttcc   3360

acgggcactg gatctcagtc cgtggagaga acaaaaccca aggcaaagat agcagagaat   3420

cctgccaacc caccagtggg tggtaaagca aagagcccca tgtttcctgc tctaggcgag   3480

gccagcagtg atgatgatct ctttcagtct gctaaaccaa aaccagcaaa gaaaacaaat   3540

ccctttcctc tcctggaaga tgaggatgac ctctttacag atcagaaagt caagaagaat   3600

gagacaaaat ccagtagtca gcaggatgtc atattaacaa cacaagatat ttttgaggat   3660

gatatatttg ctacggaagc aattaaaccc tctcagaaaa ccagagagaa ggagaaaaca   3720

ttggaatcta atttatttga tgataacatt gatatctttg ctgacttaac tgtaaaacca   3780

aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat ttgatgatga tatggatgac   3840

atcttctcca ctggtatcca ggctaagaca accaaaccaa aaagccgatc tgcacaggcc   3900

gcacctgaac caagatttga acacaaggtg tccaacatct ttgatgatcc cctgaatgcc   3960

tttggaggcc agtagagcac acagggtatc cacatgttac cctgcagcta cattgttgag   4020

ttagtgatga tattgtatat gctcatggtc ttaactggat tacaaaaagc aaatactaga   4080

acagctagct catcttttac ccaatgtact tagtattttt ctgcactggt ttaatcatgc   4140

ttaatactac aaaacaaaaa taaatatttc acagtggttg gtttgttttg tttttaaacc   4200

acagtttgat ttagttagcc ttgctggggc cataatatgc ttcagggtgt gtaaaagaag   4260

aaatctcttt gtggctttca tgggcaggga atctcagaga tagcaaatgc cacctgacca   4320

gaagtctttg ttatatggat gggaacccta acttagggct tgggcagggg aaagagaaag   4380

aagatgagag attatacttc atgagtctta gcaatatggg agcaggtttt cactgaattc   4440

tgagggtgcc tctgcatgtc ctccaaggca aagtttggca aactgtggcc cccccactgt   4500

catattttgt taataaaatt ttattggaac acaatcaca                          4539


<210>  6633
<211>  1061
<212>  PRT
<213>  Homo sapiens

<400>  6633

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala 
    50                  55                  60


Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr 
65                  70                  75                  80


Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys 
                85                  90                  95


Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala 
            100                 105                 110


Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly 
        115                 120                 125


Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu 
    130                 135                 140


Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser 
145                 150                 155                 160


Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala 
                165                 170                 175


Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala 
            180                 185                 190


Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro 
        195                 200                 205


Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp 
    210                 215                 220


Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro 
225                 230                 235                 240


Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu 
                245                 250                 255


Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr 
            260                 265                 270


Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu 
        275                 280                 285


Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro 
    290                 295                 300


Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu 
305                 310                 315                 320


Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu 
                325                 330                 335


Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys 
            340                 345                 350


Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn 
        355                 360                 365


Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly 
    370                 375                 380


Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val 
385                 390                 395                 400


Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala 
                405                 410                 415


Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe 
            420                 425                 430


Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr 
        435                 440                 445


Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro 
    450                 455                 460


Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val 
465                 470                 475                 480


Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe 
                485                 490                 495


Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg 
            500                 505                 510


Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser 
        515                 520                 525


Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu 
    530                 535                 540


Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala 
545                 550                 555                 560


Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys 
                565                 570                 575


Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu 
            580                 585                 590


Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys 
        595                 600                 605


Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu 
    610                 615                 620


Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu 
625                 630                 635                 640


Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn 
                645                 650                 655


Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp 
            660                 665                 670


Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
        675                 680                 685


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
    690                 695                 700


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
705                 710                 715                 720


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
                725                 730                 735


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
            740                 745                 750


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
        755                 760                 765


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
    770                 775                 780


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
785                 790                 795                 800


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
                805                 810                 815


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
            820                 825                 830


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
        835                 840                 845


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
    850                 855                 860


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
865                 870                 875                 880


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
                885                 890                 895


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
            900                 905                 910


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
        915                 920                 925


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
    930                 935                 940


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
945                 950                 955                 960


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
                965                 970                 975


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
            980                 985                 990


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
        995                 1000                1005


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
    1010                1015                1020


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
1025                1030                1035                1040


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
                1045                1050                1055


Ala Phe Gly Gly Gln 
            1060


<210>  6634
<211>  4801
<212>  DNA
<213>  Homo sapiens

<400>  6634
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggttacc ttatcttaca gcaaaaatct caagccctca   1680

tcagaaacaa agactcaaaa aggcttattt tcagatgagg aggactctga ggatttgttt   1740

tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc tgcctggcaa gctccccacg   1800

tcggtttccc tgtttgatga tgaagatgaa gaggataatc tttttggggg tacagctgct   1860

aagaagcaga cattgtctct acaagctcag agagaagaga aagcaaaagc ctccgagctc   1920

tccaaaaaga aagcatctgc cctgttgttc agcagtgatg aggaggacca gtggaatatt   1980

cctgcttcac agacccactt agcatctgac agcaggtcta aaggagaacc cagggattct   2040

gggaccctcc agagccagga ggccaaggct gtgaaaaaga ccagtctctt tgaggaagac   2100

aaagaagatg atctttttgc cattgccaag gacagataca tcctacctcc tattgttccc   2160

gaagttgtct gtcaagtttt gtgtatggaa agtaattcat accttcatca gatctcaaaa   2220

gaagctttac acacacaaga agaagttgag ccaaaagaag acccagagag tgtcactcct   2280

ctttgaagac gatgttgata gcggaggctc tctgtttggc tctcctccca catctgttcc   2340

tcctgcaaca aagaaaaaag agactgtctc tgaggcacca cctttgctgt tcagcgatga   2400

agaagagaag gaggcacaac ttggagtgaa gtctgtggat aagaaggttg agagtgccaa   2460

ggagtcatta aaatttggga gaactgatgt ggctgagtca gaaaaggaag gacttttgac   2520

tagatctgct caggaaacag tcaagcattc tgatttattt tcttcatcat ccccatggga   2580

caaaggaacc aagcctagaa ccaaaactgt tcttagcttg tttgatgagg aagaggataa   2640

aatggaagat caaaacatta tccaggctcc acagaaagaa gtaggaaagg gctgcgatcc   2700

tgatgcccac cccaagagca caggtgtctt ccaggatgaa gagctgcttt tcagccacaa   2760

gctccaaaag gacaatgacc cagatgttga cctttttgct ggcaccaaaa aaaccaagct   2820

gttagagcca agtgttggga gcctgtttgg ggatgatgaa gatgatgatc ttttcagctc   2880

tgccaagtcc cagcctttgg tacaagagaa aaagagagta gtgaaaaaag accactctgt   2940

taactctttc aaaaaccaga aacatcctga atccattcaa ggtagtaaag aaaaaggcat   3000

atggaagccg gaaacacctc aggactcatc aggtctcgct ccatttaaaa ccaaagaacc   3060

atccactcgg atcgggaaga tacaagcaaa tttagcgatc aacccagcgg ccttgctgcc   3120

cacagcggct tcccagatct ctgaagtaaa gcctgttttg ccagaattgg cttttccttc   3180

atctgaacac agaaggagcc acggtctgga aagtgtgcct gtccttcccg ggagtgggga   3240

ggccggtgtg agttttgatc ttccagctca ggcagacacc ttacacagtg caaacaagag   3300

ccgtgtcaag atgagaggga agcgtagacc gcagacccgt gcagctaggc ggctggctgc   3360

tcaggagtcc agcgaggctg aggacatgag cgtccccaga ggacccattg cacagtgggc   3420

tgatggcgcc atttccccaa atggccatcg gccacagctc agagcagcca gtggagaaga   3480

cagcactgag gaggccctgg cagctgccgc tgcaccttgg gaaggtggtc ctgtgcctgg   3540

agtggacaca agcccctttg caaagtctct gggtcattcc agaggggagg ctgacctttt   3600

tgattctggg gacatttttt ccacgggcac tggatctcag tccgtggaga gaacaaaacc   3660

caaggcaaag atagcagaga atcctgccaa cccaccagtg ggtggtaaag caaagagccc   3720

catgtttcct gctctaggcg aggccagcag tgatgatgat ctctttcagt ctgctaaacc   3780

aaaaccagca aagaaaacaa atccctttcc tctcctggaa gatgaggatg acctctttac   3840

agatcagaaa gtcaagaaga atgagacaaa atccagtagt cagcaggatg tcatattaac   3900

aacacaagat atttttgagg atgatatatt tgctacggaa gcaattaaac cctctcagaa   3960

aaccagagag aaggagaaaa cattggaatc taatttattt gatgataaca ttgatatctt   4020

tgctgactta actgtaaaac caaaagaaaa gtccaaaaag aaagtggaag ccaagtctat   4080

atttgatgat gatatggatg acatcttctc cactggtatc caggctaaga caaccaaacc   4140

aaaaagccga tctgcacagg ccgcacctga accaagattt gaacacaagg tgtccaacat   4200

ctttgatgat cccctgaatg cctttggagg ccagtagagc acacagggta tccacatgtt   4260

accctgcagc tacattgttg agttagtgat gatattgtat atgctcatgg tcttaactgg   4320

attacaaaaa gcaaatacta gaacagctag ctcatctttt acccaatgta cttagtattt   4380

ttctgcactg gtttaatcat gcttaatact acaaaacaaa aataaatatt tcacagtggt   4440

tggtttgttt tgtttttaaa ccacagtttg atttagttag ccttgctggg gccataatat   4500

gcttcagggt gtgtaaaaga agaaatctct ttgtggcttt catgggcagg gaatctcaga   4560

gatagcaaat gccacctgac cagaagtctt tgttatatgg atgggaaccc taacttaggg   4620

cttgggcagg ggaaagagaa agaagatgag agattatact tcatgagtct tagcaatatg   4680

ggagcaggtt ttcactgaat tctgagggtg cctctgcatg tcctccaagg caaagtttgg   4740

caaactgtgg cccccccact gtcatatttt gttaataaaa ttttattgga acacaatcac   4800

a                                                                   4801


<210>  6635
<211>  729
<212>  PRT
<213>  Homo sapiens

<400>  6635

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser 
        515                 520                 525


Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser 
    530                 535                 540


Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser 
545                 550                 555                 560


Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu 
                565                 570                 575


Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr 
            580                 585                 590


Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu 
        595                 600                 605


Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp 
    610                 615                 620


Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg 
625                 630                 635                 640


Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala 
                645                 650                 655


Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp 
            660                 665                 670


Leu Phe Ala Ile Ala Lys Asp Arg Tyr Ile Leu Pro Pro Ile Val Pro 
        675                 680                 685


Glu Val Val Cys Gln Val Leu Cys Met Glu Ser Asn Ser Tyr Leu His 
    690                 695                 700


Gln Ile Ser Lys Glu Ala Leu His Thr Gln Glu Glu Val Glu Pro Lys 
705                 710                 715                 720


Glu Asp Pro Glu Ser Val Thr Pro Leu 
                725


<210>  6636
<211>  4800
<212>  DNA
<213>  Homo sapiens

<400>  6636
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagg accagtggaa tattcctgct   2100

tcacagaccc acttagcatc tgacagcagg tctaaaggag aacccaggga ttctgggacc   2160

ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc tctttgagga agacaaagaa   2220

gatgatcttt ttgccattgc caaggacagc caaaagaaga cccagagagt gtcactcctc   2280

tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac atctgttcct   2340

cctgcaacaa agaaaaaaga gactgtctct gaggcaccac ctttgctgtt cagcgatgaa   2400

gaagagaagg aggcacaact tggagtgaag tctgtggata agaaggttga gagtgccaag   2460

gagtcattaa aatttgggag aactgatgtg gctgagtcag aaaaggaagg acttttgact   2520

agatctgctc aggaaacagt caagcattct gatttatttt cttcatcatc cccatgggac   2580

aaaggaacca agcctagaac caaaactgtt cttagcttgt ttgatgagga agaggataaa   2640

atggaagatc aaaacattat ccaggctcca cagaaagaag taggaaaggg ctgcgatcct   2700

gatgcccacc ccaagagcac aggtgtcttc caggatgaag agctgctttt cagccacaag   2760

ctccaaaagg acaatgaccc agatgttgac ctttttgctg gcaccaaaaa aaccaagctg   2820

ttagagccaa gtgttgggag cctgtttggg gatgatgaag atgatgatct tttcagctct   2880

gccaagtccc agcctttggt acaagagaaa aagagagtag tgaaaaaaga ccactctgtt   2940

aactctttca aaaaccagaa acatcctgaa tccattcaag gtagtaaaga aaaaggcata   3000

tggaagccgg aaacacctca ggactcatca ggtctcgctc catttaaaac caaagaacca   3060

tccactcgga tcgggaagat acaagcaaat ttagcgatca acccagcggc cttgctgccc   3120

acagcggctt cccagatctc tgaagtaaag cctgttttgc cagaattggc ttttccttca   3180

tctgaacaca gaaggagcca cggtctggaa agtgtgcctg tccttcccgg gagtggggag   3240

gccggtgtga gttttgatct tccagctcag gcagacacct tacacagtgc aaacaagagc   3300

cgtgtcaaga tgagagggaa gcgtagaccg cagacccgtg cagctaggcg gctggctgct   3360

caggagtcca gcgaggctga ggacatgagc gtccccagag gacccattgc acagtgggct   3420

gatggcgcca tttccccaaa tggccatcgg ccacagctca gagcagccag tggagaagac   3480

agcactgagg aggccctggc agctgccgct gcaccttggg aaggtggtcc tgtgcctgga   3540

gtggacacaa gcccctttgc aaagtctctg ggtcattcca gaggggaggc tgaccttttt   3600

gattctgggg acattttttc cacgggcact ggatctcagt ccgtggagag aacaaaaccc   3660

aaggcaaaga tagcagagaa tcctgccaac ccaccagtgg gtggtaaagc aaagagcccc   3720

atgtttcctg ctctaggcga ggccagcagt gatgatgatc tctttcagtc tgctaaacca   3780

aaaccagcaa agaaaacaaa tccctttcct ctcctggaag atgaggatga cctctttaca   3840

gatcagaaag tcaagaagaa tgagacaaaa tccagtagtc agcaggatgt catattaaca   3900

acacaagata tttttgagga tgatatattt gctacggaag caattaaacc ctctcagaaa   3960

accagagaga aggagaaaac attggaatct aatttatttg atgataacat tgatatcttt   4020

gctgacttaa ctgtaaaacc aaaagaaaag tccaaaaaga aagtggaagc caagtctata   4080

tttgatgatg atatggatga catcttctcc actggtatcc aggctaagac aaccaaacca   4140

aaaagccgat ctgcacaggc cgcacctgaa ccaagatttg aacacaaggt gtccaacatc   4200

tttgatgatc ccctgaatgc ctttggaggc cagtagagca cacagggtat ccacatgtta   4260

ccctgcagct acattgttga gttagtgatg atattgtata tgctcatggt cttaactgga   4320

ttacaaaaag caaatactag aacagctagc tcatctttta cccaatgtac ttagtatttt   4380

tctgcactgg tttaatcatg cttaatacta caaaacaaaa ataaatattt cacagtggtt   4440

ggtttgtttt gtttttaaac cacagtttga tttagttagc cttgctgggg ccataatatg   4500

cttcagggtg tgtaaaagaa gaaatctctt tgtggctttc atgggcaggg aatctcagag   4560

atagcaaatg ccacctgacc agaagtcttt gttatatgga tgggaaccct aacttagggc   4620

ttgggcaggg gaaagagaaa gaagatgaga gattatactt catgagtctt agcaatatgg   4680

gagcaggttt tcactgaatt ctgagggtgc ctctgcatgt cctccaaggc aaagtttggc   4740

aaactgtggc ccccccactg tcatattttg ttaataaaat tttattggaa cacaatcaca   4800


<210>  6637
<211>  1148
<212>  PRT
<213>  Homo sapiens

<400>  6637

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser 
                325                 330                 335


Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu 
            340                 345                 350


Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu 
        355                 360                 365


Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp 
    370                 375                 380


Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu 
385                 390                 395                 400


Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser 
                405                 410                 415


Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln 
            420                 425                 430


Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser 
        435                 440                 445


Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys 
    450                 455                 460


Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu 
465                 470                 475                 480


Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu 
                485                 490                 495


Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro 
            500                 505                 510


Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu 
        515                 520                 525


Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu 
    530                 535                 540


Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu 
545                 550                 555                 560


Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu 
                565                 570                 575


Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser 
            580                 585                 590


Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu 
        595                 600                 605


Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile 
    610                 615                 620


Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His 
625                 630                 635                 640


Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His 
                645                 650                 655


Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr 
            660                 665                 670


Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp 
        675                 680                 685


Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val 
    690                 695                 700


Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe 
705                 710                 715                 720


Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly 
                725                 730                 735


Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe 
            740                 745                 750


Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu 
        755                 760                 765


Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser 
    770                 775                 780


Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His 
785                 790                 795                 800


Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly 
                805                 810                 815


Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His 
            820                 825                 830


Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln 
        835                 840                 845


Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu 
    850                 855                 860


Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala 
865                 870                 875                 880


Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu 
                885                 890                 895


Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly 
            900                 905                 910


Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly 
        915                 920                 925


His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser 
    930                 935                 940


Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys 
945                 950                 955                 960


Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser 
                965                 970                 975


Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe 
            980                 985                 990


Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu 
        995                 1000                1005


Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn 
    1010                1015                1020


Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp 
1025                1030                1035                1040


Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln 
                1045                1050                1055


Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp 
            1060                1065                1070


Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser 
        1075                1080                1085


Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp 
    1090                1095                1100


Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg 
1105                1110                1115                1120


Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn 
                1125                1130                1135


Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            1140                1145


<210>  6638
<211>  4512
<212>  DNA
<213>  Homo sapiens

<400>  6638
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggaggaccag   1860

tggaatattc ctgcttcaca gacccactta gcatctgaca gcaggtctaa aggagaaccc   1920

agggattctg ggaccctcca gagccaggag gccaaggctg tgaaaaagac cagtctcttt   1980

gaggaagaca aagaagatga tctttttgcc attgccaagg acagccaaaa gaagacccag   2040

agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt tggctctcct   2100

cccacatctg ttcctcctgc aacaaagaaa aaagagactg tctctgaggc accacctttg   2160

ctgttcagcg atgaagaaga gaaggaggca caacttggag tgaagtctgt ggataagaag   2220

gttgagagtg ccaaggagtc attaaaattt gggagaactg atgtggctga gtcagaaaag   2280

gaaggacttt tgactagatc tgctcaggaa acagtcaagc attctgattt attttcttca   2340

tcatccccat gggacaaagg aaccaagcct agaaccaaaa ctgttcttag cttgtttgat   2400

gaggaagagg ataaaatgga agatcaaaac attatccagg ctccacagaa agaagtagga   2460

aagggctgcg atcctgatgc ccaccccaag agcacaggtg tcttccagga tgaagagctg   2520

cttttcagcc acaagctcca aaaggacaat gacccagatg ttgacctttt tgctggcacc   2580

aaaaaaacca agctgttaga gccaagtgtt gggagcctgt ttggggatga tgaagatgat   2640

gatcttttca gctctgccaa gtcccagcct ttggtacaag agaaaaagag agtagtgaaa   2700

aaagaccact ctgttaactc tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt   2760

aaagaaaaag gcatatggaa gccggaaaca cctcaggcaa atttagcgat caacccagcg   2820

gccttgctgc ccacagcggc ttcccagatc tctgaagtaa agcctgtttt gccagaattg   2880

gcttttcctt catctgaaca cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc   2940

gggagtgggg aggccggtgt gagttttgat cttccagctc aggcagacac cttacacagt   3000

gcaaacaaga gccgtgtcaa gatgagaggg aagcgtagac cgcagacccg tgcagctagg   3060

cggctggctg ctcaggagtc cagcgaggct gaggacatga gcgtccccag aggacccatt   3120

gcacagtggg ctgatggcgc catttcccca aatggccatc ggccacagct cagagcagcc   3180

agtggagaag acagcactga ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt   3240

cctgtgcctg gagtggacac aagccccttt gcaaagtctc tgggtcattc cagaggggag   3300

gctgaccttt ttgattctgg ggacattttt tccacgggca ctggatctca gtccgtggag   3360

agaacaaaac ccaaggcaaa gatagcagag aatcctgcca acccaccagt gggtggtaaa   3420

gcaaagagcc ccatgtttcc tgctctaggc gaggccagca gtgatgatga tctctttcag   3480

tctgctaaac caaaaccagc aaagaaaaca aatccctttc ctctcctgga agatgaggat   3540

gacctcttta cagatcagaa agtcaagaag aatgagacaa aatccagtag tcagcaggat   3600

gtcatattaa caacacaaga tatttttgag gatgatatat ttgctacgga agcaattaaa   3660

ccctctcaga aaaccagaga gaaggagaaa acattggaat ctaatttatt tgatgataac   3720

attgatatct ttgctgactt aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa   3780

gccaagtcta tatttgatga tgatatggat gacatcttct ccactggtat ccaggctaag   3840

acaaccaaac caaaaagccg atctgcacag gccgcacctg aaccaagatt tgaacacaag   3900

gtgtccaaca tctttgatga tcccctgaat gcctttggag gccagtagag cacacagggt   3960

atccacatgt taccctgcag ctacattgtt gagttagtga tgatattgta tatgctcatg   4020

gtcttaactg gattacaaaa agcaaatact agaacagcta gctcatcttt tacccaatgt   4080

acttagtatt tttctgcact ggtttaatca tgcttaatac tacaaaacaa aaataaatat   4140

ttcacagtgg ttggtttgtt ttgtttttaa accacagttt gatttagtta gccttgctgg   4200

ggccataata tgcttcaggg tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag   4260

ggaatctcag agatagcaaa tgccacctga ccagaagtct ttgttatatg gatgggaacc   4320

ctaacttagg gcttgggcag gggaaagaga aagaagatga gagattatac ttcatgagtc   4380

ttagcaatat gggagcaggt tttcactgaa ttctgagggt gcctctgcat gtcctccaag   4440

gcaaagtttg gcaaactgtg gcccccccac tgtcatattt tgttaataaa attttattgg   4500

aacacaatca ca                                                       4512


<210>  6639
<211>  1283
<212>  PRT
<213>  Homo sapiens

<400>  6639

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu 
                245                 250                 255


Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro 
            260                 265                 270


Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu 
        275                 280                 285


Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe 
    290                 295                 300


Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly 
305                 310                 315                 320


Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu 
                325                 330                 335


Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala 
            340                 345                 350


Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro 
        355                 360                 365


Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala 
    370                 375                 380


Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr 
385                 390                 395                 400


Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp 
                405                 410                 415


Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys 
            420                 425                 430


Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp 
        435                 440                 445


Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala 
    450                 455                 460


Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val 
465                 470                 475                 480


Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr 
                485                 490                 495


Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser 
            500                 505                 510


Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys 
        515                 520                 525


Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn 
    530                 535                 540


Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala 
545                 550                 555                 560


Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala 
                565                 570                 575


Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro 
            580                 585                 590


Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro 
        595                 600                 605


Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys 
    610                 615                 620


Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala 
625                 630                 635                 640


Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp 
                645                 650                 655


Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val 
            660                 665                 670


Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu 
        675                 680                 685


Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser 
    690                 695                 700


Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg 
705                 710                 715                 720


Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala 
                725                 730                 735


Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp 
            740                 745                 750


Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp 
        755                 760                 765


Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln 
    770                 775                 780


Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr 
785                 790                 795                 800


Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys 
                805                 810                 815


Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys 
            820                 825                 830


Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp 
        835                 840                 845


Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys 
    850                 855                 860


Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys 
865                 870                 875                 880


His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro 
                885                 890                 895


Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro 
            900                 905                 910


Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu 
        915                 920                 925


Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val 
    930                 935                 940


Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro 
945                 950                 955                 960


Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met 
                965                 970                 975


Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala 
            980                 985                 990


Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile 
        995                 1000                1005


Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln 
    1010                1015                1020


Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala 
1025                1030                1035                1040


Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser 
                1045                1050                1055


Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe 
            1060                1065                1070


Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu 
        1075                1080                1085


Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro 
    1090                1095                1100


Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala 
1105                1110                1115                1120


Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys 
                1125                1130                1135


Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr 
            1140                1145                1150


Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp 
        1155                1160                1165


Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr 
    1170                1175                1180


Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu 
1185                1190                1195                1200


Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr 
                1205                1210                1215


Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile 
            1220                1225                1230


Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys 
        1235                1240                1245


Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg 
    1250                1255                1260


Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe 
1265                1270                1275                1280


Gly Gly Gln 



<210>  6640
<211>  4300
<212>  DNA
<213>  Homo sapiens

<400>  6640
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggttacc ttatcttaca gcaaaaatct caagccctca   1680

tcagaaacaa agactcaaaa aggcttattt tcagatgagg aggactctga ggatttgttt   1740

tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc tgcctggcaa gctccccacg   1800

tcggtttccc tgtttgatga tgaagatgaa gaggataatc tttttggggg tacagctgct   1860

aagaagcaga cattgtctct acaagctcag agagaagaga aagcaaaagc ctccgagctc   1920

tccaaaaaga aagcatctgc cctgttgttc agcagtgatg aggagccaaa agaagaccca   1980

gagagtgtca ctcctctttg aagacgatgt tgatagcgga ggctctctgt ttggctctcc   2040

tcccacatct gttcctcctg caacaaagga aggacttttg actagatctg ctcaggaaac   2100

agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag   2160

aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat   2220

tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag   2280

cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga   2340

cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg   2400

gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt   2460

ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca   2520

gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc   2580

tcaggcaaat ttagcgatca acccagcggc cttgctgccc acagcggctt cccagatctc   2640

tgaagtaaag cctgttttgc cagaattggc ttttccttca tctgaacaca gaaggagcca   2700

cggtctggaa agtgtgcctg tccttcccgg gagtggggag gccggtgtga gttttgatct   2760

tccagctcag gcagacacct tacacagtgc aaacaagagc cgtgtcaaga tgagagggaa   2820

gcgtagaccg cagacccgtg cagctaggcg gctggctgct caggagtcca gcgaggctga   2880

ggacatgagc gtccccagag gacccattgc acagtgggct gatggcgcca tttccccaaa   2940

tggccatcgg ccacagctca gagcagccag tggagaagac agcactgagg aggccctggc   3000

agctgccgct gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa gcccctttgc   3060

aaagtctctg ggtcattcca gaggggaggc tgaccttttt gattctgggg acattttttc   3120

cacgggcact ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga tagcagagaa   3180

tcctgccaac ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg ctctaggcga   3240

ggccagcagt gatgatgatc tctttcagtc tgctaaacca aaaccagcaa agaaaacaaa   3300

tccctttcct ctcctggaag atgaggatga cctctttaca gatcagaaag tcaagaagaa   3360

tgagacaaaa tccagtagtc agcaggatgt catattaaca acacaagata tttttgagga   3420

tgatatattt gctacggaag caattaaacc ctctcagaaa accagagaga aggagaaaac   3480

attggaatct aatttatttg atgataacat tgatatcttt gctgacttaa ctgtaaaacc   3540

aaaagaaaag tccaaaaaga aagtggaagc caagtctata tttgatgatg atatggatga   3600

catcttctcc actggtatcc aggctaagac aaccaaacca aaaagccgat ctgcacaggc   3660

cgcacctgaa ccaagatttg aacacaaggt gtccaacatc tttgatgatc ccctgaatgc   3720

ctttggaggc cagtagagca cacagggtat ccacatgtta ccctgcagct acattgttga   3780

gttagtgatg atattgtata tgctcatggt cttaactgga ttacaaaaag caaatactag   3840

aacagctagc tcatctttta cccaatgtac ttagtatttt tctgcactgg tttaatcatg   3900

cttaatacta caaaacaaaa ataaatattt cacagtggtt ggtttgtttt gtttttaaac   3960

cacagtttga tttagttagc cttgctgggg ccataatatg cttcagggtg tgtaaaagaa   4020

gaaatctctt tgtggctttc atgggcaggg aatctcagag atagcaaatg ccacctgacc   4080

agaagtcttt gttatatgga tgggaaccct aacttagggc ttgggcaggg gaaagagaaa   4140

gaagatgaga gattatactt catgagtctt agcaatatgg gagcaggttt tcactgaatt   4200

ctgagggtgc ctctgcatgt cctccaaggc aaagtttggc aaactgtggc ccccccactg   4260

tcatattttg ttaataaaat tttattggaa cacaatcaca                         4300


<210>  6641
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6641

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6642
<211>  4689
<212>  DNA
<213>  Homo sapiens

<400>  6642
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagga ccagtggaat   1980

attcctgctt cacagaccca cttagcatct gacagcaggt ctaaaggaga acccagggat   2040

tctgggaccc tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa   2100

gacaaagaag atgatctttt tgccattgcc aaggacagcc aaaagaagac ccagagagtg   2160

tcactcctct ttgaagacga tgttgatagc ggaggctctc tgtttggctc tcctcccaca   2220

tctgttcctc ctgcaacaaa gaaaaaagag actgtctctg aggcaccacc tttgctgttc   2280

agcgatgaag aagagaagga ggcacaactt ggagtgaagt ctgtggataa gaaggttgag   2340

agtgccaagg agtcattaaa atttgggaga actgatgtgg ctgagtcaga aaaggaagga   2400

cttttgacta gatctgctca ggaaacagtc aagcattctg atttattttc ttcatcatcc   2460

ccatgggaca aaggaaccaa gcctagaacc aaaactgttc ttagcttgtt tgatgaggaa   2520

gaggataaaa tggaagatca aaacattatc caggctccac agaaagaagt aggaaagggc   2580

tgcgatcctg atgcccaccc caagagcaca ggtgtcttcc aggatgaaga gctgcttttc   2640

agccacaagc tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa   2700

accaagctgt tagagccaag tgttgggagc ctgtttgggg atgatgaaga tgatgatctt   2760

ttcagctctg ccaagtccca gcctttggta caagagaaaa agagagtagt gaaaaaagac   2820

cactctgtta actctttcaa aaaccagaaa catcctgaat ccattcaagg tagtaaagaa   2880

aaaggcatat ggaagccgga aacacctcag gactcatcag gtctcgctcc atttaaaacc   2940

aaagaaccat ccactcggat cgggaagata caagcaaatt tagcgatcaa cccagcggcc   3000

ttgctgccca cagcggcttc ccagatctct gaagtaaagc ctgttttgcc agaattggct   3060

tttccttcat ctgaacacag aaggagccac ggtctggaaa gtgtgcctgt ccttcccggg   3120

agtggggagg ccggtgtgag ttttgatctt ccagctcagg cagacacctt acacagtgca   3180

aacaagagcc gtgtcaagat gagagggaag cgtagaccgc agacccgtgc agctaggcgg   3240

ctggctgctc aggagtccag cgaggctgag gacatgagcg tccccagagg acccattgca   3300

cagtgggctg atggcgccat ttccccaaat ggccatcggc cacagctcag agcagccagt   3360

ggagaagaca gcactgagga ggccctggca gctgccgctg caccttggga aggtggtcct   3420

gtgcctggag tggacacaag cccctttgca aagtctctgg gtcattccag aggggaggct   3480

gacctttttg attctgggga cattttttcc acgggcactg gatctcagtc cgtggagaga   3540

acaaaaccca aggcaaagat agcagagaat cctgccaacc caccagtggg tggtaaagca   3600

aagagcccca tgtttcctgc tctaggcgag gccagcagtg atgatgatct ctttcagtct   3660

gctaaaccaa aaccagcaaa gaaaacaaat ccctttcctc tcctggaaga tgaggatgac   3720

ctctttacag atcagaaagt caagaagaat gagacaaaat ccagtagtca gcaggatgtc   3780

atattaacaa cacaagatat ttttgaggat gatatatttg ctacggaagc aattaaaccc   3840

tctcagaaaa ccagagagaa ggagaaaaca ttggaatcta atttatttga tgataacatt   3900

gatatctttg ctgacttaac tgtaaaacca aaagaaaagt ccaaaaagaa agtggaagcc   3960

aagtctatat ttgatgatga tatggatgac atcttctcca ctggtatcca ggctaagaca   4020

accaaaccaa aaagccgatc tgcacaggcc gcacctgaac caagatttga acacaaggtg   4080

tccaacatct ttgatgatcc cctgaatgcc tttggaggcc agtagagcac acagggtatc   4140

cacatgttac cctgcagcta cattgttgag ttagtgatga tattgtatat gctcatggtc   4200

ttaactggat tacaaaaagc aaatactaga acagctagct catcttttac ccaatgtact   4260

tagtattttt ctgcactggt ttaatcatgc ttaatactac aaaacaaaaa taaatatttc   4320

acagtggttg gtttgttttg tttttaaacc acagtttgat ttagttagcc ttgctggggc   4380

cataatatgc ttcagggtgt gtaaaagaag aaatctcttt gtggctttca tgggcaggga   4440

atctcagaga tagcaaatgc cacctgacca gaagtctttg ttatatggat gggaacccta   4500

acttagggct tgggcagggg aaagagaaag aagatgagag attatacttc atgagtctta   4560

gcaatatggg agcaggtttt cactgaattc tgagggtgcc tctgcatgtc ctccaaggca   4620

aagtttggca aactgtggcc cccccactgt catattttgt taataaaatt ttattggaac   4680

acaatcaca                                                           4689


<210>  6643
<211>  1111
<212>  PRT
<213>  Homo sapiens

<400>  6643

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala 
    50                  55                  60


Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr 
65                  70                  75                  80


Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys 
                85                  90                  95


Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala 
            100                 105                 110


Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly 
        115                 120                 125


Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu 
    130                 135                 140


Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser 
145                 150                 155                 160


Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala 
                165                 170                 175


Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala 
            180                 185                 190


Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro 
        195                 200                 205


Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp 
    210                 215                 220


Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro 
225                 230                 235                 240


Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu 
                245                 250                 255


Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr 
            260                 265                 270


Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr 
        275                 280                 285


Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln 
    290                 295                 300


Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser 
305                 310                 315                 320


Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu 
                325                 330                 335


Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu 
            340                 345                 350


Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln 
        355                 360                 365


Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser 
    370                 375                 380


Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala 
385                 390                 395                 400


Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg 
                405                 410                 415


Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr 
            420                 425                 430


Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys 
        435                 440                 445


Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    450                 455                 460


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
465                 470                 475                 480


Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu 
                485                 490                 495


Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val 
            500                 505                 510


Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr 
        515                 520                 525


Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln 
    530                 535                 540


Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp 
545                 550                 555                 560


Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu 
                565                 570                 575


Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys 
            580                 585                 590


Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly 
        595                 600                 605


Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp 
    610                 615                 620


Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu 
625                 630                 635                 640


Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp 
                645                 650                 655


Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg 
            660                 665                 670


Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His 
        675                 680                 685


Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu 
    690                 695                 700


Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro 
705                 710                 715                 720


Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala 
                725                 730                 735


Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val 
            740                 745                 750


Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly 
        755                 760                 765


Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser 
    770                 775                 780


Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser 
785                 790                 795                 800


Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg 
                805                 810                 815


Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro 
            820                 825                 830


Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly 
        835                 840                 845


His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu 
    850                 855                 860


Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly 
865                 870                 875                 880


Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu 
                885                 890                 895


Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser 
            900                 905                 910


Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro 
        915                 920                 925


Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala 
    930                 935                 940


Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro 
945                 950                 955                 960


Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp 
                965                 970                 975


Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser 
            980                 985                 990


Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp 
        995                 1000                1005


Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys 
    1010                1015                1020


Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe 
1025                1030                1035                1040


Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu 
                1045                1050                1055


Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly 
            1060                1065                1070


Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala 
        1075                1080                1085


Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro 
    1090                1095                1100


Leu Asn Ala Phe Gly Gly Gln 
1105                1110


<210>  6644
<211>  4915
<212>  DNA
<213>  Homo sapiens

<400>  6644
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagg accagtggaa tattcctgct   2100

tcacagaccc acttagcatc tgacagcagg tctaaaggag aacccaggga ttctgggacc   2160

ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc tctttgagga agacaaagaa   2220

gatgatcttt ttgccattgc caaggacaga tacatcctac ctcctattgt tcccgaagtt   2280

gtctgtcaag ttttgtgtat ggaaagtaat tcataccttc atcagatctc aaaagaagct   2340

ttacacacac aagaagaagt tgagccaaaa gaagacccag agagtgtcac tcctctttga   2400

agacgatgtt gatagcggag gctctctgtt tggctctcct cccacatctg ttcctcctgc   2460

aacaaagaaa aaagagactg tctctgaggc accacctttg ctgttcagcg atgaagaaga   2520

gaaggaggca caacttggag tgaagtctgt ggataagaag gttgagagtg ccaaggagtc   2580

attaaaattt gggagaactg atgtggctga gtcagaaaag gaaggacttt tgactagatc   2640

tgctcaggaa acagtcaagc attctgattt attttcttca tcatccccat gggacaaagg   2700

aaccaagcct agaaccaaaa ctgttcttag cttgtttgat gaggaagagg ataaaatgga   2760

agatcaaaac attatccagg ctccacagaa agaagtagga aagggctgcg atcctgatgc   2820

ccaccccaag agcacaggtg tcttccagga tgaagagctg cttttcagcc acaagctcca   2880

aaaggacaat gacccagatg ttgacctttt tgctggcacc aaaaaaacca agctgttaga   2940

gccaagtgtt gggagcctgt ttggggatga tgaagatgat gatcttttca gctctgccaa   3000

gtcccagcct ttggtacaag agaaaaagag agtagtgaaa aaagaccact ctgttaactc   3060

tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt aaagaaaaag gcatatggaa   3120

gccggaaaca cctcaggact catcaggtct cgctccattt aaaaccaaag aaccatccac   3180

tcggatcggg aagatacaag caaatttagc gatcaaccca gcggccttgc tgcccacagc   3240

ggcttcccag atctctgaag taaagcctgt tttgccagaa ttggcttttc cttcatctga   3300

acacagaagg agccacggtc tggaaagtgt gcctgtcctt cccgggagtg gggaggccgg   3360

tgtgagtttt gatcttccag ctcaggcaga caccttacac agtgcaaaca agagccgtgt   3420

caagatgaga gggaagcgta gaccgcagac ccgtgcagct aggcggctgg ctgctcagga   3480

gtccagcgag gctgaggaca tgagcgtccc cagaggaccc attgcacagt gggctgatgg   3540

cgccatttcc ccaaatggcc atcggccaca gctcagagca gccagtggag aagacagcac   3600

tgaggaggcc ctggcagctg ccgctgcacc ttgggaaggt ggtcctgtgc ctggagtgga   3660

cacaagcccc tttgcaaagt ctctgggtca ttccagaggg gaggctgacc tttttgattc   3720

tggggacatt ttttccacgg gcactggatc tcagtccgtg gagagaacaa aacccaaggc   3780

aaagatagca gagaatcctg ccaacccacc agtgggtggt aaagcaaaga gccccatgtt   3840

tcctgctcta ggcgaggcca gcagtgatga tgatctcttt cagtctgcta aaccaaaacc   3900

agcaaagaaa acaaatccct ttcctctcct ggaagatgag gatgacctct ttacagatca   3960

gaaagtcaag aagaatgaga caaaatccag tagtcagcag gatgtcatat taacaacaca   4020

agatattttt gaggatgata tatttgctac ggaagcaatt aaaccctctc agaaaaccag   4080

agagaaggag aaaacattgg aatctaattt atttgatgat aacattgata tctttgctga   4140

cttaactgta aaaccaaaag aaaagtccaa aaagaaagtg gaagccaagt ctatatttga   4200

tgatgatatg gatgacatct tctccactgg tatccaggct aagacaacca aaccaaaaag   4260

ccgatctgca caggccgcac ctgaaccaag atttgaacac aaggtgtcca acatctttga   4320

tgatcccctg aatgcctttg gaggccagta gagcacacag ggtatccaca tgttaccctg   4380

cagctacatt gttgagttag tgatgatatt gtatatgctc atggtcttaa ctggattaca   4440

aaaagcaaat actagaacag ctagctcatc ttttacccaa tgtacttagt atttttctgc   4500

actggtttaa tcatgcttaa tactacaaaa caaaaataaa tatttcacag tggttggttt   4560

gttttgtttt taaaccacag tttgatttag ttagccttgc tggggccata atatgcttca   4620

gggtgtgtaa aagaagaaat ctctttgtgg ctttcatggg cagggaatct cagagatagc   4680

aaatgccacc tgaccagaag tctttgttat atggatggga accctaactt agggcttggg   4740

caggggaaag agaaagaaga tgagagatta tacttcatga gtcttagcaa tatgggagca   4800

ggttttcact gaattctgag ggtgcctctg catgtcctcc aaggcaaagt ttggcaaact   4860

gtggcccccc cactgtcata ttttgttaat aaaattttat tggaacacaa tcaca        4915


<210>  6645
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6645

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6646
<211>  4828
<212>  DNA
<213>  Homo sapiens

<400>  6646
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaagga tttgttttct tctcaaagtg cgagtaactt aaaaggtgca   1800

tctctgctgc ctggcaagct ccccacgtcg gtttccctgt ttgatgatga agatgaagag   1860

gataatcttt ttgggggtac agctgctaag aagcagacat tgtctctaca agctcagaga   1920

gaagagaaag caaaagcctc cgagctctcc aaaaagaaag catctgccct gttgttcagc   1980

agtgatgagg aggaccagtg gaatattcct gcttcacaga cccacttagc atctgacagc   2040

aggtctaaag gagaacccag ggattctggg accctccaga gccaggaggc caaggctgtg   2100

aaaaagacca gtctctttga ggaagacaaa gaagatgatc tttttgccat tgccaaggac   2160

agatacatcc tacctcctat tgttcccgaa gttgtctgtc aagttttgtg tatggaaagt   2220

aattcatacc ttcatcagat ctcaaaagaa gctttacaca cacaagaaga agttgagcca   2280

aaagaagacc cagagagtgt cactcctctt tgaagacgat gttgatagcg gaggctctct   2340

gtttggctct cctcccacat ctgttcctcc tgcaacaaag aaaaaagaga ctgtctctga   2400

ggcaccacct ttgctgttca gcgatgaaga agagaaggag gcacaacttg gagtgaagtc   2460

tgtggataag aaggttgaga gtgccaagga gtcattaaaa tttgggagaa ctgatgtggc   2520

tgagtcagaa aaggaaggac ttttgactag atctgctcag gaaacagtca agcattctga   2580

tttattttct tcatcatccc catgggacaa aggaaccaag cctagaacca aaactgttct   2640

tagcttgttt gatgaggaag aggataaaat ggaagatcaa aacattatcc aggctccaca   2700

gaaagaagta ggaaagggct gcgatcctga tgcccacccc aagagcacag gtgtcttcca   2760

ggatgaagag ctgcttttca gccacaagct ccaaaaggac aatgacccag atgttgacct   2820

ttttgctggc accaaaaaaa ccaagctgtt agagccaagt gttgggagcc tgtttgggga   2880

tgatgaagat gatgatcttt tcagctctgc caagtcccag cctttggtac aagagaaaaa   2940

gagagtagtg aaaaaagacc actctgttaa ctctttcaaa aaccagaaac atcctgaatc   3000

cattcaaggt agtaaagaaa aaggcatatg gaagccggaa acacctcagg actcatcagg   3060

tctcgctcca tttaaaacca aagaaccatc cactcggatc gggaagatac aagcaaattt   3120

agcgatcaac ccagcggcct tgctgcccac agcggcttcc cagatctctg aagtaaagcc   3180

tgttttgcca gaattggctt ttccttcatc tgaacacaga aggagccacg gtctggaaag   3240

tgtgcctgtc cttcccggga gtggggaggc cggtgtgagt tttgatcttc cagctcaggc   3300

agacacctta cacagtgcaa acaagagccg tgtcaagatg agagggaagc gtagaccgca   3360

gacccgtgca gctaggcggc tggctgctca ggagtccagc gaggctgagg acatgagcgt   3420

ccccagagga cccattgcac agtgggctga tggcgccatt tccccaaatg gccatcggcc   3480

acagctcaga gcagccagtg gagaagacag cactgaggag gccctggcag ctgccgctgc   3540

accttgggaa ggtggtcctg tgcctggagt ggacacaagc ccctttgcaa agtctctggg   3600

tcattccaga ggggaggctg acctttttga ttctggggac attttttcca cgggcactgg   3660

atctcagtcc gtggagagaa caaaacccaa ggcaaagata gcagagaatc ctgccaaccc   3720

accagtgggt ggtaaagcaa agagccccat gtttcctgct ctaggcgagg ccagcagtga   3780

tgatgatctc tttcagtctg ctaaaccaaa accagcaaag aaaacaaatc cctttcctct   3840

cctggaagat gaggatgacc tctttacaga tcagaaagtc aagaagaatg agacaaaatc   3900

cagtagtcag caggatgtca tattaacaac acaagatatt tttgaggatg atatatttgc   3960

tacggaagca attaaaccct ctcagaaaac cagagagaag gagaaaacat tggaatctaa   4020

tttatttgat gataacattg atatctttgc tgacttaact gtaaaaccaa aagaaaagtc   4080

caaaaagaaa gtggaagcca agtctatatt tgatgatgat atggatgaca tcttctccac   4140

tggtatccag gctaagacaa ccaaaccaaa aagccgatct gcacaggccg cacctgaacc   4200

aagatttgaa cacaaggtgt ccaacatctt tgatgatccc ctgaatgcct ttggaggcca   4260

gtagagcaca cagggtatcc acatgttacc ctgcagctac attgttgagt tagtgatgat   4320

attgtatatg ctcatggtct taactggatt acaaaaagca aatactagaa cagctagctc   4380

atcttttacc caatgtactt agtatttttc tgcactggtt taatcatgct taatactaca   4440

aaacaaaaat aaatatttca cagtggttgg tttgttttgt ttttaaacca cagtttgatt   4500

tagttagcct tgctggggcc ataatatgct tcagggtgtg taaaagaaga aatctctttg   4560

tggctttcat gggcagggaa tctcagagat agcaaatgcc acctgaccag aagtctttgt   4620

tatatggatg ggaaccctaa cttagggctt gggcagggga aagagaaaga agatgagaga   4680

ttatacttca tgagtcttag caatatggga gcaggttttc actgaattct gagggtgcct   4740

ctgcatgtcc tccaaggcaa agtttggcaa actgtggccc ccccactgtc atattttgtt   4800

aataaaattt tattggaaca caatcaca                                      4828


<210>  6647
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6647

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6648
<211>  4626
<212>  DNA
<213>  Homo sapiens

<400>  6648
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagga ccagtggaat   1980

attcctgctt cacagaccca cttagcatct gacagcaggt ctaaaggaga acccagggat   2040

tctgggaccc tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa   2100

gacaaagaag atgatctttt tgccattgcc aaggacagcc aaaagaagac ccagagagtg   2160

tcactcctct ttgaagacga tgttgatagc ggaggctctc tgtttggctc tcctcccaca   2220

tctgttcctc ctgcaacaaa gaaaaaagag actgtctctg aggcaccacc tttgctgttc   2280

agcgatgaag aagagaagga ggcacaactt ggagtgaagt ctgtggataa gaaggttgag   2340

agtgccaagg agtcattaaa atttgggaga actgatgtgg ctgagtcaga aaaggaagga   2400

cttttgacta gatctgctca ggaaacagtc aagcattctg atttattttc ttcatcatcc   2460

ccatgggaca aaggaaccaa gcctagaacc aaaactgttc ttagcttgtt tgatgaggaa   2520

gaggataaaa tggaagatca aaacattatc caggctccac agaaagaagt aggaaagggc   2580

tgcgatcctg atgcccaccc caagagcaca ggtgtcttcc aggatgaaga gctgcttttc   2640

agccacaagc tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa   2700

accaagctgt tagagccaag tgttgggagc ctgtttgggg atgatgaaga tgatgatctt   2760

ttcagctctg ccaagtccca gcctttggta caagagaaaa agagagtagt gaaaaaagac   2820

cactctgtta actctttcaa aaaccagaaa catcctgaat ccattcaagg tagtaaagaa   2880

aaaggcatat ggaagccgga aacacctcag gcaaatttag cgatcaaccc agcggccttg   2940

ctgcccacag cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt   3000

ccttcatctg aacacagaag gagccacggt ctggaaagtg tgcctgtcct tcccgggagt   3060

ggggaggccg gtgtgagttt tgatcttcca gctcaggcag acaccttaca cagtgcaaac   3120

aagagccgtg tcaagatgag agggaagcgt agaccgcaga cccgtgcagc taggcggctg   3180

gctgctcagg agtccagcga ggctgaggac atgagcgtcc ccagaggacc cattgcacag   3240

tgggctgatg gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga   3300

gaagacagca ctgaggaggc cctggcagct gccgctgcac cttgggaagg tggtcctgtg   3360

cctggagtgg acacaagccc ctttgcaaag tctctgggtc attccagagg ggaggctgac   3420

ctttttgatt ctggggacat tttttccacg ggcactggat ctcagtccgt ggagagaaca   3480

aaacccaagg caaagatagc agagaatcct gccaacccac cagtgggtgg taaagcaaag   3540

agccccatgt ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct   3600

aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc tggaagatga ggatgacctc   3660

tttacagatc agaaagtcaa gaagaatgag acaaaatcca gtagtcagca ggatgtcata   3720

ttaacaacac aagatatttt tgaggatgat atatttgcta cggaagcaat taaaccctct   3780

cagaaaacca gagagaagga gaaaacattg gaatctaatt tatttgatga taacattgat   3840

atctttgctg acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag   3900

tctatatttg atgatgatat ggatgacatc ttctccactg gtatccaggc taagacaacc   3960

aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa gatttgaaca caaggtgtcc   4020

aacatctttg atgatcccct gaatgccttt ggaggccagt agagcacaca gggtatccac   4080

atgttaccct gcagctacat tgttgagtta gtgatgatat tgtatatgct catggtctta   4140

actggattac aaaaagcaaa tactagaaca gctagctcat cttttaccca atgtacttag   4200

tatttttctg cactggttta atcatgctta atactacaaa acaaaaataa atatttcaca   4260

gtggttggtt tgttttgttt ttaaaccaca gtttgattta gttagccttg ctggggccat   4320

aatatgcttc agggtgtgta aaagaagaaa tctctttgtg gctttcatgg gcagggaatc   4380

tcagagatag caaatgccac ctgaccagaa gtctttgtta tatggatggg aaccctaact   4440

tagggcttgg gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca   4500

atatgggagc aggttttcac tgaattctga gggtgcctct gcatgtcctc caaggcaaag   4560

tttggcaaac tgtggccccc ccactgtcat attttgttaa taaaatttta ttggaacaca   4620

atcaca                                                              4626


<210>  6649
<211>  1090
<212>  PRT
<213>  Homo sapiens

<400>  6649

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala 
    50                  55                  60


Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr 
65                  70                  75                  80


Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys 
                85                  90                  95


Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala 
            100                 105                 110


Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly 
        115                 120                 125


Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu 
    130                 135                 140


Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser 
145                 150                 155                 160


Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala 
                165                 170                 175


Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala 
            180                 185                 190


Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro 
        195                 200                 205


Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp 
    210                 215                 220


Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro 
225                 230                 235                 240


Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu 
                245                 250                 255


Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr 
            260                 265                 270


Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr 
        275                 280                 285


Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln 
    290                 295                 300


Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser 
305                 310                 315                 320


Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu 
                325                 330                 335


Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu 
            340                 345                 350


Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln 
        355                 360                 365


Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser 
    370                 375                 380


Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala 
385                 390                 395                 400


Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg 
                405                 410                 415


Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr 
            420                 425                 430


Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys 
        435                 440                 445


Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    450                 455                 460


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
465                 470                 475                 480


Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu 
                485                 490                 495


Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val 
            500                 505                 510


Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr 
        515                 520                 525


Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln 
    530                 535                 540


Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp 
545                 550                 555                 560


Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu 
                565                 570                 575


Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys 
            580                 585                 590


Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly 
        595                 600                 605


Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp 
    610                 615                 620


Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu 
625                 630                 635                 640


Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp 
                645                 650                 655


Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg 
            660                 665                 670


Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His 
        675                 680                 685


Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu 
    690                 695                 700


Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr 
705                 710                 715                 720


Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala 
                725                 730                 735


Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro 
            740                 745                 750


Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala 
        755                 760                 765


Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg 
    770                 775                 780


Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln 
785                 790                 795                 800


Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala 
                805                 810                 815


Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu 
            820                 825                 830


Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala 
        835                 840                 845


Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro 
    850                 855                 860


Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp 
865                 870                 875                 880


Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg 
                885                 890                 895


Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val 
            900                 905                 910


Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser 
        915                 920                 925


Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys 
    930                 935                 940


Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp 
945                 950                 955                 960


Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val 
                965                 970                 975


Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu 
            980                 985                 990


Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu 
        995                 1000                1005


Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val 
    1010                1015                1020


Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe 
1025                1030                1035                1040


Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr 
                1045                1050                1055


Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe 
            1060                1065                1070


Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly 
        1075                1080                1085


Gly Gln 
    1090


<210>  6650
<211>  4602
<212>  DNA
<213>  Homo sapiens

<400>  6650
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggat ttgttttctt ctcaaagtgc gagtaactta   1680

aaaggtgcat ctctgctgcc tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa   1740

gatgaagagg ataatctttt tgggggtaca gctgctaaga agcagacatt gtctctacaa   1800

gctcagagag aagagaaagc aaaagcctcc gagctctcca aaaagaaagc atctgccctg   1860

ttgttcagca gtgatgagga ggaccagtgg aatattcctg cttcacagac ccacttagca   1920

tctgacagca ggtctaaagg agaacccagg gattctggga ccctccagag ccaggaggcc   1980

aaggctgtga aaaagaccag tctctttgag gaagacaaag aagatgatct ttttgccatt   2040

gccaaggaca gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat   2100

agcggaggct ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa   2160

gagactgtct ctgaggcacc acctttgctg ttcagcgatg aagaagagaa ggaggcacaa   2220

cttggagtga agtctgtgga taagaaggtt gagagtgcca aggagtcatt aaaatttggg   2280

agaactgatg tggctgagtc agaaaaggaa ggacttttga ctagatctgc tcaggaaaca   2340

gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac caagcctaga   2400

accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga tcaaaacatt   2460

atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca ccccaagagc   2520

acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa ggacaatgac   2580

ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg   2640

agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc ccagcctttg   2700

gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt caaaaaccag   2760

aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct   2820

caggactcat caggtctcgc tccatttaaa accaaagaac catccactcg gatcgggaag   2880

atacaagcaa atttagcgat caacccagcg gccttgctgc ccacagcggc ttcccagatc   2940

tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca cagaaggagc   3000

cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt gagttttgat   3060

cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa gatgagaggg   3120

aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc cagcgaggct   3180

gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc catttcccca   3240

aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga ggaggccctg   3300

gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacac aagccccttt   3360

gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg ggacattttt   3420

tccacgggca ctggatctca gtccgtggag agaacaaaac ccaaggcaaa gatagcagag   3480

aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc tgctctaggc   3540

gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc aaagaaaaca   3600

aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa agtcaagaag   3660

aatgagacaa aatccagtag tcagcaggat gtcatattaa caacacaaga tatttttgag   3720

gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga gaaggagaaa   3780

acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt aactgtaaaa   3840

ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga tgatatggat   3900

gacatcttct ccactggtat ccaggctaag acaaccaaac caaaaagccg atctgcacag   3960

gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga tcccctgaat   4020

gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag ctacattgtt   4080

gagttagtga tgatattgta tatgctcatg gtcttaactg gattacaaaa agcaaatact   4140

agaacagcta gctcatcttt tacccaatgt acttagtatt tttctgcact ggtttaatca   4200

tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt ttgtttttaa   4260

accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg tgtgtaaaag   4320

aagaaatctc tttgtggctt tcatgggcag ggaatctcag agatagcaaa tgccacctga   4380

ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcttgggcag gggaaagaga   4440

aagaagatga gagattatac ttcatgagtc ttagcaatat gggagcaggt tttcactgaa   4500

ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg gcccccccac   4560

tgtcatattt tgttaataaa attttattgg aacacaatca ca                      4602


<210>  6651
<211>  1082
<212>  PRT
<213>  Homo sapiens

<400>  6651

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala 
    50                  55                  60


Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr 
65                  70                  75                  80


Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys 
                85                  90                  95


Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala 
            100                 105                 110


Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly 
        115                 120                 125


Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu 
    130                 135                 140


Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser 
145                 150                 155                 160


Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala 
                165                 170                 175


Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala 
            180                 185                 190


Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro 
        195                 200                 205


Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp 
    210                 215                 220


Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro 
225                 230                 235                 240


Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu 
                245                 250                 255


Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr 
            260                 265                 270


Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu 
        275                 280                 285


Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro 
    290                 295                 300


Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu 
305                 310                 315                 320


Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu 
                325                 330                 335


Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys 
            340                 345                 350


Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn 
        355                 360                 365


Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly 
    370                 375                 380


Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val 
385                 390                 395                 400


Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala 
                405                 410                 415


Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe 
            420                 425                 430


Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr 
        435                 440                 445


Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro 
    450                 455                 460


Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val 
465                 470                 475                 480


Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe 
                485                 490                 495


Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg 
            500                 505                 510


Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser 
        515                 520                 525


Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu 
    530                 535                 540


Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala 
545                 550                 555                 560


Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys 
                565                 570                 575


Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu 
            580                 585                 590


Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys 
        595                 600                 605


Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu 
    610                 615                 620


Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu 
625                 630                 635                 640


Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn 
                645                 650                 655


Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp 
            660                 665                 670


Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr 
        675                 680                 685


Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile 
    690                 695                 700


Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val 
705                 710                 715                 720


Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg 
                725                 730                 735


Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala 
            740                 745                 750


Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala 
        755                 760                 765


Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg 
    770                 775                 780


Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met 
785                 790                 795                 800


Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser 
                805                 810                 815


Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser 
            820                 825                 830


Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro 
        835                 840                 845


Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser 
    850                 855                 860


Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly 
865                 870                 875                 880


Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala 
                885                 890                 895


Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met 
            900                 905                 910


Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser 
        915                 920                 925


Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu 
    930                 935                 940


Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr 
945                 950                 955                 960


Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe 
                965                 970                 975


Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr 
            980                 985                 990


Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile 
        995                 1000                1005


Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys 
    1010                1015                1020


Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe 
1025                1030                1035                1040


Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala 
                1045                1050                1055


Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe 
            1060                1065                1070


Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        1075                1080


<210>  6652
<211>  4737
<212>  DNA
<213>  Homo sapiens

<400>  6652
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagg accagtggaa tattcctgct   2100

tcacagaccc acttagcatc tgacagcagg tctaaaggag aacccaggga ttctgggacc   2160

ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc tctttgagga agacaaagaa   2220

gatgatcttt ttgccattgc caaggacagc caaaagaaga cccagagagt gtcactcctc   2280

tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac atctgttcct   2340

cctgcaacaa agaaaaaaga gactgtctct gaggcaccac ctttgctgtt cagcgatgaa   2400

gaagagaagg aggcacaact tggagtgaag tctgtggata agaaggttga gagtgccaag   2460

gagtcattaa aatttgggag aactgatgtg gctgagtcag aaaaggaagg acttttgact   2520

agatctgctc aggaaacagt caagcattct gatttatttt cttcatcatc cccatgggac   2580

aaaggaacca agcctagaac caaaactgtt cttagcttgt ttgatgagga agaggataaa   2640

atggaagatc aaaacattat ccaggctcca cagaaagaag taggaaaggg ctgcgatcct   2700

gatgcccacc ccaagagcac aggtgtcttc caggatgaag agctgctttt cagccacaag   2760

ctccaaaagg acaatgaccc agatgttgac ctttttgctg gcaccaaaaa aaccaagctg   2820

ttagagccaa gtgttgggag cctgtttggg gatgatgaag atgatgatct tttcagctct   2880

gccaagtccc agcctttggt acaagagaaa aagagagtag tgaaaaaaga ccactctgtt   2940

aactctttca aaaaccagaa acatcctgaa tccattcaag gtagtaaaga aaaaggcata   3000

tggaagccgg aaacacctca ggcaaattta gcgatcaacc cagcggcctt gctgcccaca   3060

gcggcttccc agatctctga agtaaagcct gttttgccag aattggcttt tccttcatct   3120

gaacacagaa ggagccacgg tctggaaagt gtgcctgtcc ttcccgggag tggggaggcc   3180

ggtgtgagtt ttgatcttcc agctcaggca gacaccttac acagtgcaaa caagagccgt   3240

gtcaagatga gagggaagcg tagaccgcag acccgtgcag ctaggcggct ggctgctcag   3300

gagtccagcg aggctgagga catgagcgtc cccagaggac ccattgcaca gtgggctgat   3360

ggcgccattt ccccaaatgg ccatcggcca cagctcagag cagccagtgg agaagacagc   3420

actgaggagg ccctggcagc tgccgctgca ccttgggaag gtggtcctgt gcctggagtg   3480

gacacaagcc cctttgcaaa gtctctgggt cattccagag gggaggctga cctttttgat   3540

tctggggaca ttttttccac gggcactgga tctcagtccg tggagagaac aaaacccaag   3600

gcaaagatag cagagaatcc tgccaaccca ccagtgggtg gtaaagcaaa gagccccatg   3660

tttcctgctc taggcgaggc cagcagtgat gatgatctct ttcagtctgc taaaccaaaa   3720

ccagcaaaga aaacaaatcc ctttcctctc ctggaagatg aggatgacct ctttacagat   3780

cagaaagtca agaagaatga gacaaaatcc agtagtcagc aggatgtcat attaacaaca   3840

caagatattt ttgaggatga tatatttgct acggaagcaa ttaaaccctc tcagaaaacc   3900

agagagaagg agaaaacatt ggaatctaat ttatttgatg ataacattga tatctttgct   3960

gacttaactg taaaaccaaa agaaaagtcc aaaaagaaag tggaagccaa gtctatattt   4020

gatgatgata tggatgacat cttctccact ggtatccagg ctaagacaac caaaccaaaa   4080

agccgatctg cacaggccgc acctgaacca agatttgaac acaaggtgtc caacatcttt   4140

gatgatcccc tgaatgcctt tggaggccag tagagcacac agggtatcca catgttaccc   4200

tgcagctaca ttgttgagtt agtgatgata ttgtatatgc tcatggtctt aactggatta   4260

caaaaagcaa atactagaac agctagctca tcttttaccc aatgtactta gtatttttct   4320

gcactggttt aatcatgctt aatactacaa aacaaaaata aatatttcac agtggttggt   4380

ttgttttgtt tttaaaccac agtttgattt agttagcctt gctggggcca taatatgctt   4440

cagggtgtgt aaaagaagaa atctctttgt ggctttcatg ggcagggaat ctcagagata   4500

gcaaatgcca cctgaccaga agtctttgtt atatggatgg gaaccctaac ttagggcttg   4560

ggcaggggaa agagaaagaa gatgagagat tatacttcat gagtcttagc aatatgggag   4620

caggttttca ctgaattctg agggtgcctc tgcatgtcct ccaaggcaaa gtttggcaaa   4680

ctgtggcccc cccactgtca tattttgtta ataaaatttt attggaacac aatcaca      4737


<210>  6653
<211>  1127
<212>  PRT
<213>  Homo sapiens

<400>  6653

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser 
                325                 330                 335


Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu 
            340                 345                 350


Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu 
        355                 360                 365


Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp 
    370                 375                 380


Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu 
385                 390                 395                 400


Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser 
                405                 410                 415


Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln 
            420                 425                 430


Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser 
        435                 440                 445


Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys 
    450                 455                 460


Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu 
465                 470                 475                 480


Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu 
                485                 490                 495


Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro 
            500                 505                 510


Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu 
        515                 520                 525


Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu 
    530                 535                 540


Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu 
545                 550                 555                 560


Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu 
                565                 570                 575


Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser 
            580                 585                 590


Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu 
        595                 600                 605


Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile 
    610                 615                 620


Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His 
625                 630                 635                 640


Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His 
                645                 650                 655


Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr 
            660                 665                 670


Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp 
        675                 680                 685


Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val 
    690                 695                 700


Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe 
705                 710                 715                 720


Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly 
                725                 730                 735


Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala 
            740                 745                 750


Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val 
        755                 760                 765


Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly 
    770                 775                 780


Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser 
785                 790                 795                 800


Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser 
                805                 810                 815


Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg 
            820                 825                 830


Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro 
        835                 840                 845


Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly 
    850                 855                 860


His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu 
865                 870                 875                 880


Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly 
                885                 890                 895


Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu 
            900                 905                 910


Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser 
        915                 920                 925


Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro 
    930                 935                 940


Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala 
945                 950                 955                 960


Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro 
                965                 970                 975


Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp 
            980                 985                 990


Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser 
        995                 1000                1005


Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp 
    1010                1015                1020


Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys 
1025                1030                1035                1040


Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe 
                1045                1050                1055


Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu 
            1060                1065                1070


Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly 
        1075                1080                1085


Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala 
    1090                1095                1100


Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro 
1105                1110                1115                1120


Leu Asn Ala Phe Gly Gly Gln 
                1125


<210>  6654
<211>  4488
<212>  DNA
<213>  Homo sapiens

<400>  6654
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggatttgt tttcttctca aagtgcgagt   1560

aacttaaaag gtgcatctct gctgcctggc aagctcccca cgtcggtttc cctgtttgat   1620

gatgaagatg aagaggataa tctttttggg ggtacagctg ctaagaagca gacattgtct   1680

ctacaagctc agagagaaga gaaagcaaaa gcctccgagc tctccaaaaa gaaagcatct   1740

gccctgttgt tcagcagtga tgaggaggac cagtggaata ttcctgcttc acagacccac   1800

ttagcatctg acagcaggtc taaaggagaa cccagggatt ctgggaccct ccagagccag   1860

gaggccaagg ctgtgaaaaa gaccagtctc tttgaggaag acaaagaaga tgatcttttt   1920

gccattgcca aggacagcca aaagaagacc cagagagtgt cactcctctt tgaagacgat   1980

gttgatagcg gaggctctct gtttggctct cctcccacat ctgttcctcc tgcaacaaag   2040

aaaaaagaga ctgtctctga ggcaccacct ttgctgttca gcgatgaaga agagaaggag   2100

gcacaacttg gagtgaagtc tgtggataag aaggttgaga gtgccaagga gtcattaaaa   2160

tttgggagaa ctgatgtggc tgagtcagaa aaggaaggac ttttgactag atctgctcag   2220

gaaacagtca agcattctga tttattttct tcatcatccc catgggacaa aggaaccaag   2280

cctagaacca aaactgttct tagcttgttt gatgaggaag aggataaaat ggaagatcaa   2340

aacattatcc aggctccaca gaaagaagta ggaaagggct gcgatcctga tgcccacccc   2400

aagagcacag gtgtcttcca ggatgaagag ctgcttttca gccacaagct ccaaaaggac   2460

aatgacccag atgttgacct ttttgctggc accaaaaaaa ccaagctgtt agagccaagt   2520

gttgggagcc tgtttgggga tgatgaagat gatgatcttt tcagctctgc caagtcccag   2580

cctttggtac aagagaaaaa gagagtagtg aaaaaagacc actctgttaa ctctttcaaa   2640

aaccagaaac atcctgaatc cattcaaggt agtaaagaaa aaggcatatg gaagccggaa   2700

acacctcagg actcatcagg tctcgctcca tttaaaacca aagaaccatc cactcggatc   2760

gggaagatac aagcaaattt agcgatcaac ccagcggcct tgctgcccac agcggcttcc   2820

cagatctctg aagtaaagcc tgttttgcca gaattggctt ttccttcatc tgaacacaga   2880

aggagccacg gtctggaaag tgtgcctgtc cttcccggga gtggggaggc cggtgtgagt   2940

tttgatcttc cagctcaggc agacacctta cacagtgcaa acaagagccg tgtcaagatg   3000

agagggaagc gtagaccgca gacccgtgca gctaggcggc tggctgctca ggagtccagc   3060

gaggctgagg acatgagcgt ccccagagga cccattgcac agtgggctga tggcgccatt   3120

tccccaaatg gccatcggcc acagctcaga gcagccagtg gagaagacag cactgaggag   3180

gccctggcag ctgccgctgc accttgggaa ggtggtcctg tgcctggagt ggacacaagc   3240

ccctttgcaa agtctctggg tcattccaga ggggaggctg acctttttga ttctggggac   3300

attttttcca cgggcactgg atctcagtcc gtggagagaa caaaacccaa ggcaaagata   3360

gcagagaatc ctgccaaccc accagtgggt ggtaaagcaa agagccccat gtttcctgct   3420

ctaggcgagg ccagcagtga tgatgatctc tttcagtctg ctaaaccaaa accagcaaag   3480

aaaacaaatc cctttcctct cctggaagat gaggatgacc tctttacaga tcagaaagtc   3540

aagaagaatg agacaaaatc cagtagtcag caggatgtca tattaacaac acaagatatt   3600

tttgaggatg atatatttgc tacggaagca attaaaccct ctcagaaaac cagagagaag   3660

gagaaaacat tggaatctaa tttatttgat gataacattg atatctttgc tgacttaact   3720

gtaaaaccaa aagaaaagtc caaaaagaaa gtggaagcca agtctatatt tgatgatgat   3780

atggatgaca tcttctccac tggtatccag gctaagacaa ccaaaccaaa aagccgatct   3840

gcacaggccg cacctgaacc aagatttgaa cacaaggtgt ccaacatctt tgatgatccc   3900

ctgaatgcct ttggaggcca gtagagcaca cagggtatcc acatgttacc ctgcagctac   3960

attgttgagt tagtgatgat attgtatatg ctcatggtct taactggatt acaaaaagca   4020

aatactagaa cagctagctc atcttttacc caatgtactt agtatttttc tgcactggtt   4080

taatcatgct taatactaca aaacaaaaat aaatatttca cagtggttgg tttgttttgt   4140

ttttaaacca cagtttgatt tagttagcct tgctggggcc ataatatgct tcagggtgtg   4200

taaaagaaga aatctctttg tggctttcat gggcagggaa tctcagagat agcaaatgcc   4260

acctgaccag aagtctttgt tatatggatg ggaaccctaa cttagggctt gggcagggga   4320

aagagaaaga agatgagaga ttatacttca tgagtcttag caatatggga gcaggttttc   4380

actgaattct gagggtgcct ctgcatgtcc tccaaggcaa agtttggcaa actgtggccc   4440

ccccactgtc atattttgtt aataaaattt tattggaaca caatcaca                4488


<210>  6655
<211>  1275
<212>  PRT
<213>  Homo sapiens

<400>  6655

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu 
                245                 250                 255


Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro 
            260                 265                 270


Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu 
        275                 280                 285


Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe 
    290                 295                 300


Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly 
305                 310                 315                 320


Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu 
                325                 330                 335


Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala 
            340                 345                 350


Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro 
        355                 360                 365


Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala 
    370                 375                 380


Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr 
385                 390                 395                 400


Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp 
                405                 410                 415


Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys 
            420                 425                 430


Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp 
        435                 440                 445


Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala 
    450                 455                 460


Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp 
465                 470                 475                 480


Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu 
                485                 490                 495


Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu 
            500                 505                 510


Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser 
        515                 520                 525


Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys 
    530                 535                 540


Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp 
545                 550                 555                 560


Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys 
                565                 570                 575


Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala 
            580                 585                 590


Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe 
        595                 600                 605


Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu 
    610                 615                 620


Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro 
625                 630                 635                 640


Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala 
                645                 650                 655


Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly 
            660                 665                 670


Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys 
        675                 680                 685


Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr 
    690                 695                 700


Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser 
705                 710                 715                 720


Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser 
                725                 730                 735


Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln 
            740                 745                 750


Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro 
        755                 760                 765


Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys 
    770                 775                 780


Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys 
785                 790                 795                 800


Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp 
                805                 810                 815


Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln 
            820                 825                 830


Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys 
        835                 840                 845


Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile 
    850                 855                 860


Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys 
865                 870                 875                 880


Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala 
                885                 890                 895


Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu 
            900                 905                 910


Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg 
        915                 920                 925


Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu 
    930                 935                 940


Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser 
945                 950                 955                 960


Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr 
                965                 970                 975


Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp 
            980                 985                 990


Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile 
        995                 1000                1005


Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp 
    1010                1015                1020


Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly 
1025                1030                1035                1040


Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His 
                1045                1050                1055


Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr 
            1060                1065                1070


Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile 
        1075                1080                1085


Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro 
    1090                1095                1100


Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln 
1105                1110                1115                1120


Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu 
                1125                1130                1135


Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu 
            1140                1145                1150


Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile 
        1155                1160                1165


Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys 
    1170                1175                1180


Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn 
1185                1190                1195                1200


Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys 
                1205                1210                1215


Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile 
            1220                1225                1230


Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser 
        1235                1240                1245


Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile 
    1250                1255                1260


Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
1265                1270                1275


<210>  6656
<211>  4363
<212>  DNA
<213>  Homo sapiens

<400>  6656
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggttacc ttatcttaca gcaaaaatct caagccctca   1680

tcagaaacaa agactcaaaa aggcttattt tcagatgagg aggactctga ggatttgttt   1740

tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc tgcctggcaa gctccccacg   1800

tcggtttccc tgtttgatga tgaagatgaa gaggataatc tttttggggg tacagctgct   1860

aagaagcaga cattgtctct acaagctcag agagaagaga aagcaaaagc ctccgagctc   1920

tccaaaaaga aagcatctgc cctgttgttc agcagtgatg aggagccaaa agaagaccca   1980

gagagtgtca ctcctctttg aagacgatgt tgatagcgga ggctctctgt ttggctctcc   2040

tcccacatct gttcctcctg caacaaagga aggacttttg actagatctg ctcaggaaac   2100

agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag   2160

aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat   2220

tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag   2280

cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga   2340

cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg   2400

gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt   2460

ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca   2520

gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc   2580

tcaggactca tcaggtctcg ctccatttaa aaccaaagaa ccatccactc ggatcgggaa   2640

gatacaagca aatttagcga tcaacccagc ggccttgctg cccacagcgg cttcccagat   2700

ctctgaagta aagcctgttt tgccagaatt ggcttttcct tcatctgaac acagaaggag   2760

ccacggtctg gaaagtgtgc ctgtccttcc cgggagtggg gaggccggtg tgagttttga   2820

tcttccagct caggcagaca ccttacacag tgcaaacaag agccgtgtca agatgagagg   2880

gaagcgtaga ccgcagaccc gtgcagctag gcggctggct gctcaggagt ccagcgaggc   2940

tgaggacatg agcgtcccca gaggacccat tgcacagtgg gctgatggcg ccatttcccc   3000

aaatggccat cggccacagc tcagagcagc cagtggagaa gacagcactg aggaggccct   3060

ggcagctgcc gctgcacctt gggaaggtgg tcctgtgcct ggagtggaca caagcccctt   3120

tgcaaagtct ctgggtcatt ccagagggga ggctgacctt tttgattctg gggacatttt   3180

ttccacgggc actggatctc agtccgtgga gagaacaaaa cccaaggcaa agatagcaga   3240

gaatcctgcc aacccaccag tgggtggtaa agcaaagagc cccatgtttc ctgctctagg   3300

cgaggccagc agtgatgatg atctctttca gtctgctaaa ccaaaaccag caaagaaaac   3360

aaatcccttt cctctcctgg aagatgagga tgacctcttt acagatcaga aagtcaagaa   3420

gaatgagaca aaatccagta gtcagcagga tgtcatatta acaacacaag atatttttga   3480

ggatgatata tttgctacgg aagcaattaa accctctcag aaaaccagag agaaggagaa   3540

aacattggaa tctaatttat ttgatgataa cattgatatc tttgctgact taactgtaaa   3600

accaaaagaa aagtccaaaa agaaagtgga agccaagtct atatttgatg atgatatgga   3660

tgacatcttc tccactggta tccaggctaa gacaaccaaa ccaaaaagcc gatctgcaca   3720

ggccgcacct gaaccaagat ttgaacacaa ggtgtccaac atctttgatg atcccctgaa   3780

tgcctttgga ggccagtaga gcacacaggg tatccacatg ttaccctgca gctacattgt   3840

tgagttagtg atgatattgt atatgctcat ggtcttaact ggattacaaa aagcaaatac   3900

tagaacagct agctcatctt ttacccaatg tacttagtat ttttctgcac tggtttaatc   3960

atgcttaata ctacaaaaca aaaataaata tttcacagtg gttggtttgt tttgttttta   4020

aaccacagtt tgatttagtt agccttgctg gggccataat atgcttcagg gtgtgtaaaa   4080

gaagaaatct ctttgtggct ttcatgggca gggaatctca gagatagcaa atgccacctg   4140

accagaagtc tttgttatat ggatgggaac cctaacttag ggcttgggca ggggaaagag   4200

aaagaagatg agagattata cttcatgagt cttagcaata tgggagcagg ttttcactga   4260

attctgaggg tgcctctgca tgtcctccaa ggcaaagttt ggcaaactgt ggccccccca   4320

ctgtcatatt ttgttaataa aattttattg gaacacaatc aca                     4363


<210>  6657
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6657

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6658
<211>  4713
<212>  DNA
<213>  Homo sapiens

<400>  6658
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaagga tttgttttct tctcaaagtg cgagtaactt aaaaggtgca   1800

tctctgctgc ctggcaagct ccccacgtcg gtttccctgt ttgatgatga agatgaagag   1860

gataatcttt ttgggggtac agctgctaag aagcagacat tgtctctaca agctcagaga   1920

gaagagaaag caaaagcctc cgagctctcc aaaaagaaag catctgccct gttgttcagc   1980

agtgatgagg aggaccagtg gaatattcct gcttcacaga cccacttagc atctgacagc   2040

aggtctaaag gagaacccag ggattctggg accctccaga gccaggaggc caaggctgtg   2100

aaaaagacca gtctctttga ggaagacaaa gaagatgatc tttttgccat tgccaaggac   2160

agccaaaaga agacccagag agtgtcactc ctctttgaag acgatgttga tagcggaggc   2220

tctctgtttg gctctcctcc cacatctgtt cctcctgcaa caaagaaaaa agagactgtc   2280

tctgaggcac cacctttgct gttcagcgat gaagaagaga aggaggcaca acttggagtg   2340

aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat taaaatttgg gagaactgat   2400

gtggctgagt cagaaaagga aggacttttg actagatctg ctcaggaaac agtcaagcat   2460

tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag aaccaaaact   2520

gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat tatccaggct   2580

ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag cacaggtgtc   2640

ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga cccagatgtt   2700

gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg gagcctgttt   2760

ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt ggtacaagag   2820

aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca gaaacatcct   2880

gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc tcaggactca   2940

tcaggtctcg ctccatttaa aaccaaagaa ccatccactc ggatcgggaa gatacaagca   3000

aatttagcga tcaacccagc ggccttgctg cccacagcgg cttcccagat ctctgaagta   3060

aagcctgttt tgccagaatt ggcttttcct tcatctgaac acagaaggag ccacggtctg   3120

gaaagtgtgc ctgtccttcc cgggagtggg gaggccggtg tgagttttga tcttccagct   3180

caggcagaca ccttacacag tgcaaacaag agccgtgtca agatgagagg gaagcgtaga   3240

ccgcagaccc gtgcagctag gcggctggct gctcaggagt ccagcgaggc tgaggacatg   3300

agcgtcccca gaggacccat tgcacagtgg gctgatggcg ccatttcccc aaatggccat   3360

cggccacagc tcagagcagc cagtggagaa gacagcactg aggaggccct ggcagctgcc   3420

gctgcacctt gggaaggtgg tcctgtgcct ggagtggaca caagcccctt tgcaaagtct   3480

ctgggtcatt ccagagggga ggctgacctt tttgattctg gggacatttt ttccacgggc   3540

actggatctc agtccgtgga gagaacaaaa cccaaggcaa agatagcaga gaatcctgcc   3600

aacccaccag tgggtggtaa agcaaagagc cccatgtttc ctgctctagg cgaggccagc   3660

agtgatgatg atctctttca gtctgctaaa ccaaaaccag caaagaaaac aaatcccttt   3720

cctctcctgg aagatgagga tgacctcttt acagatcaga aagtcaagaa gaatgagaca   3780

aaatccagta gtcagcagga tgtcatatta acaacacaag atatttttga ggatgatata   3840

tttgctacgg aagcaattaa accctctcag aaaaccagag agaaggagaa aacattggaa   3900

tctaatttat ttgatgataa cattgatatc tttgctgact taactgtaaa accaaaagaa   3960

aagtccaaaa agaaagtgga agccaagtct atatttgatg atgatatgga tgacatcttc   4020

tccactggta tccaggctaa gacaaccaaa ccaaaaagcc gatctgcaca ggccgcacct   4080

gaaccaagat ttgaacacaa ggtgtccaac atctttgatg atcccctgaa tgcctttgga   4140

ggccagtaga gcacacaggg tatccacatg ttaccctgca gctacattgt tgagttagtg   4200

atgatattgt atatgctcat ggtcttaact ggattacaaa aagcaaatac tagaacagct   4260

agctcatctt ttacccaatg tacttagtat ttttctgcac tggtttaatc atgcttaata   4320

ctacaaaaca aaaataaata tttcacagtg gttggtttgt tttgttttta aaccacagtt   4380

tgatttagtt agccttgctg gggccataat atgcttcagg gtgtgtaaaa gaagaaatct   4440

ctttgtggct ttcatgggca gggaatctca gagatagcaa atgccacctg accagaagtc   4500

tttgttatat ggatgggaac cctaacttag ggcttgggca ggggaaagag aaagaagatg   4560

agagattata cttcatgagt cttagcaata tgggagcagg ttttcactga attctgaggg   4620

tgcctctgca tgtcctccaa ggcaaagttt ggcaaactgt ggccccccca ctgtcatatt   4680

ttgttaataa aattttattg gaacacaatc aca                                4713


<210>  6659
<211>  1119
<212>  PRT
<213>  Homo sapiens

<400>  6659

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly 
                325                 330                 335


Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp 
            340                 345                 350


Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys 
        355                 360                 365


Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser 
    370                 375                 380


Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu 
385                 390                 395                 400


Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp 
                405                 410                 415


Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln 
            420                 425                 430


Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu 
        435                 440                 445


Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg 
    450                 455                 460


Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe 
465                 470                 475                 480


Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr 
                485                 490                 495


Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu 
            500                 505                 510


Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys 
        515                 520                 525


Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu 
    530                 535                 540


Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu 
545                 550                 555                 560


Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys 
                565                 570                 575


Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln 
            580                 585                 590


Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro 
        595                 600                 605


Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu 
    610                 615                 620


Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe 
625                 630                 635                 640


Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu 
                645                 650                 655


Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln 
            660                 665                 670


Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val 
        675                 680                 685


Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys 
    690                 695                 700


Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu 
705                 710                 715                 720


Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln 
                725                 730                 735


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            740                 745                 750


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        755                 760                 765


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    770                 775                 780


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
785                 790                 795                 800


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                805                 810                 815


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            820                 825                 830


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        835                 840                 845


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    850                 855                 860


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
865                 870                 875                 880


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                885                 890                 895


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            900                 905                 910


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        915                 920                 925


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    930                 935                 940


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
945                 950                 955                 960


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                965                 970                 975


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            980                 985                 990


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        995                 1000                1005


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    1010                1015                1020


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
1025                1030                1035                1040


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                1045                1050                1055


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            1060                1065                1070


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        1075                1080                1085


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    1090                1095                1100


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
1105                1110                1115


<210>  6660
<211>  4540
<212>  DNA
<213>  Homo sapiens

<400>  6660
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggatttgt tttcttctca aagtgcgagt   1560

aacttaaaag gtgcatctct gctgcctggc aagctcccca cgtcggtttc cctgtttgat   1620

gatgaagatg aagaggataa tctttttggg ggtacagctg ctaagaagca gacattgtct   1680

ctacaagctc agagagaaga gaaagcaaaa gcctccgagc tctccaaaaa gaaagcatct   1740

gccctgttgt tcagcagtga tgaggaggac cagtggaata ttcctgcttc acagacccac   1800

ttagcatctg acagcaggtc taaaggagaa cccagggatt ctgggaccct ccagagccag   1860

gaggccaagg ctgtgaaaaa gaccagtctc tttgaggaag acaaagaaga tgatcttttt   1920

gccattgcca aggacagata catcctacct cctattgttc ccgaagttgt ctgtcaagtt   1980

ttgtgtatgg aaagtaattc ataccttcat cagatctcaa aagaagcttt acacacacaa   2040

gaagaagttg agccaaaaga agacccagag agtgtcactc ctctttgaag acgatgttga   2100

tagcggaggc tctctgtttg gctctcctcc cacatctgtt cctcctgcaa caaagaaaaa   2160

agagactgtc tctgaggcac cacctttgct gttcagcgat gaagaagaga aggaggcaca   2220

acttggagtg aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat taaaatttgg   2280

gagaactgat gtggctgagt cagaaaagga aggacttttg actagatctg ctcaggaaac   2340

agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag   2400

aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat   2460

tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag   2520

cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga   2580

cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg   2640

gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt   2700

ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca   2760

gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc   2820

tcaggcaaat ttagcgatca acccagcggc cttgctgccc acagcggctt cccagatctc   2880

tgaagtaaag cctgttttgc cagaattggc ttttccttca tctgaacaca gaaggagcca   2940

cggtctggaa agtgtgcctg tccttcccgg gagtggggag gccggtgtga gttttgatct   3000

tccagctcag gcagacacct tacacagtgc aaacaagagc cgtgtcaaga tgagagggaa   3060

gcgtagaccg cagacccgtg cagctaggcg gctggctgct caggagtcca gcgaggctga   3120

ggacatgagc gtccccagag gacccattgc acagtgggct gatggcgcca tttccccaaa   3180

tggccatcgg ccacagctca gagcagccag tggagaagac agcactgagg aggccctggc   3240

agctgccgct gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa gcccctttgc   3300

aaagtctctg ggtcattcca gaggggaggc tgaccttttt gattctgggg acattttttc   3360

cacgggcact ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga tagcagagaa   3420

tcctgccaac ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg ctctaggcga   3480

ggccagcagt gatgatgatc tctttcagtc tgctaaacca aaaccagcaa agaaaacaaa   3540

tccctttcct ctcctggaag atgaggatga cctctttaca gatcagaaag tcaagaagaa   3600

tgagacaaaa tccagtagtc agcaggatgt catattaaca acacaagata tttttgagga   3660

tgatatattt gctacggaag caattaaacc ctctcagaaa accagagaga aggagaaaac   3720

attggaatct aatttatttg atgataacat tgatatcttt gctgacttaa ctgtaaaacc   3780

aaaagaaaag tccaaaaaga aagtggaagc caagtctata tttgatgatg atatggatga   3840

catcttctcc actggtatcc aggctaagac aaccaaacca aaaagccgat ctgcacaggc   3900

cgcacctgaa ccaagatttg aacacaaggt gtccaacatc tttgatgatc ccctgaatgc   3960

ctttggaggc cagtagagca cacagggtat ccacatgtta ccctgcagct acattgttga   4020

gttagtgatg atattgtata tgctcatggt cttaactgga ttacaaaaag caaatactag   4080

aacagctagc tcatctttta cccaatgtac ttagtatttt tctgcactgg tttaatcatg   4140

cttaatacta caaaacaaaa ataaatattt cacagtggtt ggtttgtttt gtttttaaac   4200

cacagtttga tttagttagc cttgctgggg ccataatatg cttcagggtg tgtaaaagaa   4260

gaaatctctt tgtggctttc atgggcaggg aatctcagag atagcaaatg ccacctgacc   4320

agaagtcttt gttatatgga tgggaaccct aacttagggc ttgggcaggg gaaagagaaa   4380

gaagatgaga gattatactt catgagtctt agcaatatgg gagcaggttt tcactgaatt   4440

ctgagggtgc ctctgcatgt cctccaaggc aaagtttggc aaactgtggc ccccccactg   4500

tcatattttg ttaataaaat tttattggaa cacaatcaca                         4540


<210>  6661
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6661

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6662
<211>  4425
<212>  DNA
<213>  Homo sapiens

<400>  6662
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggatttgt tttcttctca aagtgcgagt   1560

aacttaaaag gtgcatctct gctgcctggc aagctcccca cgtcggtttc cctgtttgat   1620

gatgaagatg aagaggataa tctttttggg ggtacagctg ctaagaagca gacattgtct   1680

ctacaagctc agagagaaga gaaagcaaaa gcctccgagc tctccaaaaa gaaagcatct   1740

gccctgttgt tcagcagtga tgaggaggac cagtggaata ttcctgcttc acagacccac   1800

ttagcatctg acagcaggtc taaaggagaa cccagggatt ctgggaccct ccagagccag   1860

gaggccaagg ctgtgaaaaa gaccagtctc tttgaggaag acaaagaaga tgatcttttt   1920

gccattgcca aggacagcca aaagaagacc cagagagtgt cactcctctt tgaagacgat   1980

gttgatagcg gaggctctct gtttggctct cctcccacat ctgttcctcc tgcaacaaag   2040

aaaaaagaga ctgtctctga ggcaccacct ttgctgttca gcgatgaaga agagaaggag   2100

gcacaacttg gagtgaagtc tgtggataag aaggttgaga gtgccaagga gtcattaaaa   2160

tttgggagaa ctgatgtggc tgagtcagaa aaggaaggac ttttgactag atctgctcag   2220

gaaacagtca agcattctga tttattttct tcatcatccc catgggacaa aggaaccaag   2280

cctagaacca aaactgttct tagcttgttt gatgaggaag aggataaaat ggaagatcaa   2340

aacattatcc aggctccaca gaaagaagta ggaaagggct gcgatcctga tgcccacccc   2400

aagagcacag gtgtcttcca ggatgaagag ctgcttttca gccacaagct ccaaaaggac   2460

aatgacccag atgttgacct ttttgctggc accaaaaaaa ccaagctgtt agagccaagt   2520

gttgggagcc tgtttgggga tgatgaagat gatgatcttt tcagctctgc caagtcccag   2580

cctttggtac aagagaaaaa gagagtagtg aaaaaagacc actctgttaa ctctttcaaa   2640

aaccagaaac atcctgaatc cattcaaggt agtaaagaaa aaggcatatg gaagccggaa   2700

acacctcagg caaatttagc gatcaaccca gcggccttgc tgcccacagc ggcttcccag   2760

atctctgaag taaagcctgt tttgccagaa ttggcttttc cttcatctga acacagaagg   2820

agccacggtc tggaaagtgt gcctgtcctt cccgggagtg gggaggccgg tgtgagtttt   2880

gatcttccag ctcaggcaga caccttacac agtgcaaaca agagccgtgt caagatgaga   2940

gggaagcgta gaccgcagac ccgtgcagct aggcggctgg ctgctcagga gtccagcgag   3000

gctgaggaca tgagcgtccc cagaggaccc attgcacagt gggctgatgg cgccatttcc   3060

ccaaatggcc atcggccaca gctcagagca gccagtggag aagacagcac tgaggaggcc   3120

ctggcagctg ccgctgcacc ttgggaaggt ggtcctgtgc ctggagtgga cacaagcccc   3180

tttgcaaagt ctctgggtca ttccagaggg gaggctgacc tttttgattc tggggacatt   3240

ttttccacgg gcactggatc tcagtccgtg gagagaacaa aacccaaggc aaagatagca   3300

gagaatcctg ccaacccacc agtgggtggt aaagcaaaga gccccatgtt tcctgctcta   3360

ggcgaggcca gcagtgatga tgatctcttt cagtctgcta aaccaaaacc agcaaagaaa   3420

acaaatccct ttcctctcct ggaagatgag gatgacctct ttacagatca gaaagtcaag   3480

aagaatgaga caaaatccag tagtcagcag gatgtcatat taacaacaca agatattttt   3540

gaggatgata tatttgctac ggaagcaatt aaaccctctc agaaaaccag agagaaggag   3600

aaaacattgg aatctaattt atttgatgat aacattgata tctttgctga cttaactgta   3660

aaaccaaaag aaaagtccaa aaagaaagtg gaagccaagt ctatatttga tgatgatatg   3720

gatgacatct tctccactgg tatccaggct aagacaacca aaccaaaaag ccgatctgca   3780

caggccgcac ctgaaccaag atttgaacac aaggtgtcca acatctttga tgatcccctg   3840

aatgcctttg gaggccagta gagcacacag ggtatccaca tgttaccctg cagctacatt   3900

gttgagttag tgatgatatt gtatatgctc atggtcttaa ctggattaca aaaagcaaat   3960

actagaacag ctagctcatc ttttacccaa tgtacttagt atttttctgc actggtttaa   4020

tcatgcttaa tactacaaaa caaaaataaa tatttcacag tggttggttt gttttgtttt   4080

taaaccacag tttgatttag ttagccttgc tggggccata atatgcttca gggtgtgtaa   4140

aagaagaaat ctctttgtgg ctttcatggg cagggaatct cagagatagc aaatgccacc   4200

tgaccagaag tctttgttat atggatggga accctaactt agggcttggg caggggaaag   4260

agaaagaaga tgagagatta tacttcatga gtcttagcaa tatgggagca ggttttcact   4320

gaattctgag ggtgcctctg catgtcctcc aaggcaaagt ttggcaaact gtggcccccc   4380

cactgtcata ttttgttaat aaaattttat tggaacacaa tcaca                   4425


<210>  6663
<211>  1254
<212>  PRT
<213>  Homo sapiens

<400>  6663

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu 
                245                 250                 255


Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro 
            260                 265                 270


Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu 
        275                 280                 285


Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe 
    290                 295                 300


Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly 
305                 310                 315                 320


Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu 
                325                 330                 335


Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala 
            340                 345                 350


Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro 
        355                 360                 365


Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala 
    370                 375                 380


Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr 
385                 390                 395                 400


Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp 
                405                 410                 415


Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys 
            420                 425                 430


Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp 
        435                 440                 445


Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala 
    450                 455                 460


Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp 
465                 470                 475                 480


Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu 
                485                 490                 495


Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu 
            500                 505                 510


Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser 
        515                 520                 525


Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys 
    530                 535                 540


Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp 
545                 550                 555                 560


Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys 
                565                 570                 575


Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala 
            580                 585                 590


Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe 
        595                 600                 605


Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu 
    610                 615                 620


Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro 
625                 630                 635                 640


Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala 
                645                 650                 655


Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly 
            660                 665                 670


Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys 
        675                 680                 685


Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr 
    690                 695                 700


Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser 
705                 710                 715                 720


Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser 
                725                 730                 735


Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln 
            740                 745                 750


Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro 
        755                 760                 765


Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys 
    770                 775                 780


Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys 
785                 790                 795                 800


Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp 
                805                 810                 815


Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln 
            820                 825                 830


Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys 
        835                 840                 845


Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile 
    850                 855                 860


Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala 
865                 870                 875                 880


Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu 
                885                 890                 895


Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu 
            900                 905                 910


Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe 
        915                 920                 925


Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg 
    930                 935                 940


Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg 
945                 950                 955                 960


Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg 
                965                 970                 975


Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His 
            980                 985                 990


Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala 
        995                 1000                1005


Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val 
    1010                1015                1020


Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala 
1025                1030                1035                1040


Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln 
                1045                1050                1055


Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala 
            1060                1065                1070


Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu 
        1075                1080                1085


Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys 
    1090                1095                1100


Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp 
1105                1110                1115                1120


Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser 
                1125                1130                1135


Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile 
            1140                1145                1150


Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu 
        1155                1160                1165


Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala 
    1170                1175                1180


Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala 
1185                1190                1195                1200


Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile 
                1205                1210                1215


Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro 
            1220                1225                1230


Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu 
        1235                1240                1245


Asn Ala Phe Gly Gly Gln 
    1250


<210>  6664
<211>  4603
<212>  DNA
<213>  Homo sapiens

<400>  6664
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggatttgt tttcttctca aagtgcgagt   1560

aacttaaaag gtgcatctct gctgcctggc aagctcccca cgtcggtttc cctgtttgat   1620

gatgaagatg aagaggataa tctttttggg ggtacagctg ctaagaagca gacattgtct   1680

ctacaagctc agagagaaga gaaagcaaaa gcctccgagc tctccaaaaa gaaagcatct   1740

gccctgttgt tcagcagtga tgaggaggac cagtggaata ttcctgcttc acagacccac   1800

ttagcatctg acagcaggtc taaaggagaa cccagggatt ctgggaccct ccagagccag   1860

gaggccaagg ctgtgaaaaa gaccagtctc tttgaggaag acaaagaaga tgatcttttt   1920

gccattgcca aggacagata catcctacct cctattgttc ccgaagttgt ctgtcaagtt   1980

ttgtgtatgg aaagtaattc ataccttcat cagatctcaa aagaagcttt acacacacaa   2040

gaagaagttg agccaaaaga agacccagag agtgtcactc ctctttgaag acgatgttga   2100

tagcggaggc tctctgtttg gctctcctcc cacatctgtt cctcctgcaa caaagaaaaa   2160

agagactgtc tctgaggcac cacctttgct gttcagcgat gaagaagaga aggaggcaca   2220

acttggagtg aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat taaaatttgg   2280

gagaactgat gtggctgagt cagaaaagga aggacttttg actagatctg ctcaggaaac   2340

agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa ccaagcctag   2400

aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag atcaaaacat   2460

tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc accccaagag   2520

cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa aggacaatga   2580

cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc caagtgttgg   2640

gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt cccagccttt   2700

ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt tcaaaaacca   2760

gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc cggaaacacc   2820

tcaggactca tcaggtctcg ctccatttaa aaccaaagaa ccatccactc ggatcgggaa   2880

gatacaagca aatttagcga tcaacccagc ggccttgctg cccacagcgg cttcccagat   2940

ctctgaagta aagcctgttt tgccagaatt ggcttttcct tcatctgaac acagaaggag   3000

ccacggtctg gaaagtgtgc ctgtccttcc cgggagtggg gaggccggtg tgagttttga   3060

tcttccagct caggcagaca ccttacacag tgcaaacaag agccgtgtca agatgagagg   3120

gaagcgtaga ccgcagaccc gtgcagctag gcggctggct gctcaggagt ccagcgaggc   3180

tgaggacatg agcgtcccca gaggacccat tgcacagtgg gctgatggcg ccatttcccc   3240

aaatggccat cggccacagc tcagagcagc cagtggagaa gacagcactg aggaggccct   3300

ggcagctgcc gctgcacctt gggaaggtgg tcctgtgcct ggagtggaca caagcccctt   3360

tgcaaagtct ctgggtcatt ccagagggga ggctgacctt tttgattctg gggacatttt   3420

ttccacgggc actggatctc agtccgtgga gagaacaaaa cccaaggcaa agatagcaga   3480

gaatcctgcc aacccaccag tgggtggtaa agcaaagagc cccatgtttc ctgctctagg   3540

cgaggccagc agtgatgatg atctctttca gtctgctaaa ccaaaaccag caaagaaaac   3600

aaatcccttt cctctcctgg aagatgagga tgacctcttt acagatcaga aagtcaagaa   3660

gaatgagaca aaatccagta gtcagcagga tgtcatatta acaacacaag atatttttga   3720

ggatgatata tttgctacgg aagcaattaa accctctcag aaaaccagag agaaggagaa   3780

aacattggaa tctaatttat ttgatgataa cattgatatc tttgctgact taactgtaaa   3840

accaaaagaa aagtccaaaa agaaagtgga agccaagtct atatttgatg atgatatgga   3900

tgacatcttc tccactggta tccaggctaa gacaaccaaa ccaaaaagcc gatctgcaca   3960

ggccgcacct gaaccaagat ttgaacacaa ggtgtccaac atctttgatg atcccctgaa   4020

tgcctttgga ggccagtaga gcacacaggg tatccacatg ttaccctgca gctacattgt   4080

tgagttagtg atgatattgt atatgctcat ggtcttaact ggattacaaa aagcaaatac   4140

tagaacagct agctcatctt ttacccaatg tacttagtat ttttctgcac tggtttaatc   4200

atgcttaata ctacaaaaca aaaataaata tttcacagtg gttggtttgt tttgttttta   4260

aaccacagtt tgatttagtt agccttgctg gggccataat atgcttcagg gtgtgtaaaa   4320

gaagaaatct ctttgtggct ttcatgggca gggaatctca gagatagcaa atgccacctg   4380

accagaagtc tttgttatat ggatgggaac cctaacttag ggcttgggca ggggaaagag   4440

aaagaagatg agagattata cttcatgagt cttagcaata tgggagcagg ttttcactga   4500

attctgaggg tgcctctgca tgtcctccaa ggcaaagttt ggcaaactgt ggccccccca   4560

ctgtcatatt ttgttaataa aattttattg gaacacaatc aca                     4603


<210>  6665
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6665

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6666
<211>  4741
<212>  DNA
<213>  Homo sapiens

<400>  6666
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agaaaagaag cagacctaca    960

tcgtttgcag atgagctggc tgcccgcatc aagggggatg ccatgggtcg agtggacgag   1020

gagccgacaa ccttaccctc aggagaagca aaacctcgga agacactcaa agagaagaag   1080

gaaaggagaa ctccttcaga cgatgaagag gataacttat tcgcaccccc caagctgacc   1140

gacgaggact tctcgccatt tggctctgga ggtggcctgt tcagtggcgg caaggggcta   1200

tttgatgatg aggacgagga gagtgacctc ttcacggaag cctcccagga tcggcaagct   1260

ggagcctctg ttaaggagga gtcttcatca tccaaacctg gaaagaaaat cccagcagga   1320

gctgtttctg tatttttagg agacacggat gtgtttggtg ctgcctccgt tccatcactg   1380

aaggagccac agaagcctga gcagcccact ccaaggaaaa gcccctatgg tccccctccc   1440

actggcctct ttgatgatga tgatggtgat gatgatgacg actttttctc ggcaccccac   1500

agcaaacctt ctaaaacacg caaagtccaa tccactgccg atatctttgg tgacgaagaa   1560

ggagatctgt tcaaagaaaa agccgtagca tcgccagaag ccactgtgag tcagacagat   1620

gaaaataaag caagagcaga aaaaaaggtt accttatctt acagcaaaaa tctcaagccc   1680

tcatcagaaa caaagactca aaaaggctta ttttcagatg aggaggactc tgaggatttg   1740

ttttcttctc aaagtgcgag taacttaaaa ggtgcatctc tgctgcctgg caagctcccc   1800

acgtcggttt ccctgtttga tgatgaagat gaagaggata atctttttgg gggtacagct   1860

gctaagaagc agacattgtc tctacaagct cagagagaag agaaagcaaa agcctccgag   1920

ctctccaaaa agaaagcatc tgccctgttg ttcagcagtg atgaggagga ccagtggaat   1980

attcctgctt cacagaccca cttagcatct gacagcaggt ctaaaggaga acccagggat   2040

tctgggaccc tccagagcca ggaggccaag gctgtgaaaa agaccagtct ctttgaggaa   2100

gacaaagaag atgatctttt tgccattgcc aaggacagat acatcctacc tcctattgtt   2160

cccgaagttg tctgtcaagt tttgtgtatg gaaagtaatt cataccttca tcagatctca   2220

aaagaagctt tacacacaca agaagaagtt gagccaaaag aagacccaga gagtgtcact   2280

cctctttgaa gacgatgttg atagcggagg ctctctgttt ggctctcctc ccacatctgt   2340

tcctcctgca acaaagaaaa aagagactgt ctctgaggca ccacctttgc tgttcagcga   2400

tgaagaagag aaggaggcac aacttggagt gaagtctgtg gataagaagg ttgagagtgc   2460

caaggagtca ttaaaatttg ggagaactga tgtggctgag tcagaaaagg aaggactttt   2520

gactagatct gctcaggaaa cagtcaagca ttctgattta ttttcttcat catccccatg   2580

ggacaaagga accaagccta gaaccaaaac tgttcttagc ttgtttgatg aggaagagga   2640

taaaatggaa gatcaaaaca ttatccaggc tccacagaaa gaagtaggaa agggctgcga   2700

tcctgatgcc caccccaaga gcacaggtgt cttccaggat gaagagctgc ttttcagcca   2760

caagctccaa aaggacaatg acccagatgt tgaccttttt gctggcacca aaaaaaccaa   2820

gctgttagag ccaagtgttg ggagcctgtt tggggatgat gaagatgatg atcttttcag   2880

ctctgccaag tcccagcctt tggtacaaga gaaaaagaga gtagtgaaaa aagaccactc   2940

tgttaactct ttcaaaaacc agaaacatcc tgaatccatt caaggtagta aagaaaaagg   3000

catatggaag ccggaaacac ctcaggcaaa tttagcgatc aacccagcgg ccttgctgcc   3060

cacagcggct tcccagatct ctgaagtaaa gcctgttttg ccagaattgg cttttccttc   3120

atctgaacac agaaggagcc acggtctgga aagtgtgcct gtccttcccg ggagtgggga   3180

ggccggtgtg agttttgatc ttccagctca ggcagacacc ttacacagtg caaacaagag   3240

ccgtgtcaag atgagaggga agcgtagacc gcagacccgt gcagctaggc ggctggctgc   3300

tcaggagtcc agcgaggctg aggacatgag cgtccccaga ggacccattg cacagtgggc   3360

tgatggcgcc atttccccaa atggccatcg gccacagctc agagcagcca gtggagaaga   3420

cagcactgag gaggccctgg cagctgccgc tgcaccttgg gaaggtggtc ctgtgcctgg   3480

agtggacaca agcccctttg caaagtctct gggtcattcc agaggggagg ctgacctttt   3540

tgattctggg gacatttttt ccacgggcac tggatctcag tccgtggaga gaacaaaacc   3600

caaggcaaag atagcagaga atcctgccaa cccaccagtg ggtggtaaag caaagagccc   3660

catgtttcct gctctaggcg aggccagcag tgatgatgat ctctttcagt ctgctaaacc   3720

aaaaccagca aagaaaacaa atccctttcc tctcctggaa gatgaggatg acctctttac   3780

agatcagaaa gtcaagaaga atgagacaaa atccagtagt cagcaggatg tcatattaac   3840

aacacaagat atttttgagg atgatatatt tgctacggaa gcaattaaac cctctcagaa   3900

aaccagagag aaggagaaaa cattggaatc taatttattt gatgataaca ttgatatctt   3960

tgctgactta actgtaaaac caaaagaaaa gtccaaaaag aaagtggaag ccaagtctat   4020

atttgatgat gatatggatg acatcttctc cactggtatc caggctaaga caaccaaacc   4080

aaaaagccga tctgcacagg ccgcacctga accaagattt gaacacaagg tgtccaacat   4140

ctttgatgat cccctgaatg cctttggagg ccagtagagc acacagggta tccacatgtt   4200

accctgcagc tacattgttg agttagtgat gatattgtat atgctcatgg tcttaactgg   4260

attacaaaaa gcaaatacta gaacagctag ctcatctttt acccaatgta cttagtattt   4320

ttctgcactg gtttaatcat gcttaatact acaaaacaaa aataaatatt tcacagtggt   4380

tggtttgttt tgtttttaaa ccacagtttg atttagttag ccttgctggg gccataatat   4440

gcttcagggt gtgtaaaaga agaaatctct ttgtggcttt catgggcagg gaatctcaga   4500

gatagcaaat gccacctgac cagaagtctt tgttatatgg atgggaaccc taacttaggg   4560

cttgggcagg ggaaagagaa agaagatgag agattatact tcatgagtct tagcaatatg   4620

ggagcaggtt ttcactgaat tctgagggtg cctctgcatg tcctccaagg caaagtttgg   4680

caaactgtgg cccccccact gtcatatttt gttaataaaa ttttattgga acacaatcac   4740

a                                                                   4741


<210>  6667
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6667

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6668
<211>  4252
<212>  DNA
<213>  Homo sapiens

<400>  6668
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggagccaaaa   1860

gaagacccag agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt   1920

tggctctcct cccacatctg ttcctcctgc aacaaaggaa ggacttttga ctagatctgc   1980

tcaggaaaca gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac   2040

caagcctaga accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga   2100

tcaaaacatt atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca   2160

ccccaagagc acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa   2220

ggacaatgac ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc   2280

aagtgttggg agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc   2340

ccagcctttg gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt   2400

caaaaaccag aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc   2460

ggaaacacct caggactcat caggtctcgc tccatttaaa accaaagaac catccactcg   2520

gatcgggaag atacaagcaa atttagcgat caacccagcg gccttgctgc ccacagcggc   2580

ttcccagatc tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca   2640

cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt   2700

gagttttgat cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa   2760

gatgagaggg aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc   2820

cagcgaggct gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc   2880

catttcccca aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga   2940

ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacac   3000

aagccccttt gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg   3060

ggacattttt tccacgggca ctggatctca gtccgtggag agaacaaaac ccaaggcaaa   3120

gatagcagag aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc   3180

tgctctaggc gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc   3240

aaagaaaaca aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa   3300

agtcaagaag aatgagacaa aatccagtag tcagcaggat gtcatattaa caacacaaga   3360

tatttttgag gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga   3420

gaaggagaaa acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt   3480

aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga   3540

tgatatggat gacatcttct ccactggtat ccaggctaag acaaccaaac caaaaagccg   3600

atctgcacag gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga   3660

tcccctgaat gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag   3720

ctacattgtt gagttagtga tgatattgta tatgctcatg gtcttaactg gattacaaaa   3780

agcaaatact agaacagcta gctcatcttt tacccaatgt acttagtatt tttctgcact   3840

ggtttaatca tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt   3900

ttgtttttaa accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg   3960

tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag ggaatctcag agatagcaaa   4020

tgccacctga ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcttgggcag   4080

gggaaagaga aagaagatga gagattatac ttcatgagtc ttagcaatat gggagcaggt   4140

tttcactgaa ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg   4200

gcccccccac tgtcatattt tgttaataaa attttattgg aacacaatca ca           4252


<210>  6669
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6669

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6670
<211>  4575
<212>  DNA
<213>  Homo sapiens

<400>  6670
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggaggaccag   1860

tggaatattc ctgcttcaca gacccactta gcatctgaca gcaggtctaa aggagaaccc   1920

agggattctg ggaccctcca gagccaggag gccaaggctg tgaaaaagac cagtctcttt   1980

gaggaagaca aagaagatga tctttttgcc attgccaagg acagccaaaa gaagacccag   2040

agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt tggctctcct   2100

cccacatctg ttcctcctgc aacaaagaaa aaagagactg tctctgaggc accacctttg   2160

ctgttcagcg atgaagaaga gaaggaggca caacttggag tgaagtctgt ggataagaag   2220

gttgagagtg ccaaggagtc attaaaattt gggagaactg atgtggctga gtcagaaaag   2280

gaaggacttt tgactagatc tgctcaggaa acagtcaagc attctgattt attttcttca   2340

tcatccccat gggacaaagg aaccaagcct agaaccaaaa ctgttcttag cttgtttgat   2400

gaggaagagg ataaaatgga agatcaaaac attatccagg ctccacagaa agaagtagga   2460

aagggctgcg atcctgatgc ccaccccaag agcacaggtg tcttccagga tgaagagctg   2520

cttttcagcc acaagctcca aaaggacaat gacccagatg ttgacctttt tgctggcacc   2580

aaaaaaacca agctgttaga gccaagtgtt gggagcctgt ttggggatga tgaagatgat   2640

gatcttttca gctctgccaa gtcccagcct ttggtacaag agaaaaagag agtagtgaaa   2700

aaagaccact ctgttaactc tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt   2760

aaagaaaaag gcatatggaa gccggaaaca cctcaggact catcaggtct cgctccattt   2820

aaaaccaaag aaccatccac tcggatcggg aagatacaag caaatttagc gatcaaccca   2880

gcggccttgc tgcccacagc ggcttcccag atctctgaag taaagcctgt tttgccagaa   2940

ttggcttttc cttcatctga acacagaagg agccacggtc tggaaagtgt gcctgtcctt   3000

cccgggagtg gggaggccgg tgtgagtttt gatcttccag ctcaggcaga caccttacac   3060

agtgcaaaca agagccgtgt caagatgaga gggaagcgta gaccgcagac ccgtgcagct   3120

aggcggctgg ctgctcagga gtccagcgag gctgaggaca tgagcgtccc cagaggaccc   3180

attgcacagt gggctgatgg cgccatttcc ccaaatggcc atcggccaca gctcagagca   3240

gccagtggag aagacagcac tgaggaggcc ctggcagctg ccgctgcacc ttgggaaggt   3300

ggtcctgtgc ctggagtgga cacaagcccc tttgcaaagt ctctgggtca ttccagaggg   3360

gaggctgacc tttttgattc tggggacatt ttttccacgg gcactggatc tcagtccgtg   3420

gagagaacaa aacccaaggc aaagatagca gagaatcctg ccaacccacc agtgggtggt   3480

aaagcaaaga gccccatgtt tcctgctcta ggcgaggcca gcagtgatga tgatctcttt   3540

cagtctgcta aaccaaaacc agcaaagaaa acaaatccct ttcctctcct ggaagatgag   3600

gatgacctct ttacagatca gaaagtcaag aagaatgaga caaaatccag tagtcagcag   3660

gatgtcatat taacaacaca agatattttt gaggatgata tatttgctac ggaagcaatt   3720

aaaccctctc agaaaaccag agagaaggag aaaacattgg aatctaattt atttgatgat   3780

aacattgata tctttgctga cttaactgta aaaccaaaag aaaagtccaa aaagaaagtg   3840

gaagccaagt ctatatttga tgatgatatg gatgacatct tctccactgg tatccaggct   3900

aagacaacca aaccaaaaag ccgatctgca caggccgcac ctgaaccaag atttgaacac   3960

aaggtgtcca acatctttga tgatcccctg aatgcctttg gaggccagta gagcacacag   4020

ggtatccaca tgttaccctg cagctacatt gttgagttag tgatgatatt gtatatgctc   4080

atggtcttaa ctggattaca aaaagcaaat actagaacag ctagctcatc ttttacccaa   4140

tgtacttagt atttttctgc actggtttaa tcatgcttaa tactacaaaa caaaaataaa   4200

tatttcacag tggttggttt gttttgtttt taaaccacag tttgatttag ttagccttgc   4260

tggggccata atatgcttca gggtgtgtaa aagaagaaat ctctttgtgg ctttcatggg   4320

cagggaatct cagagatagc aaatgccacc tgaccagaag tctttgttat atggatggga   4380

accctaactt agggcttggg caggggaaag agaaagaaga tgagagatta tacttcatga   4440

gtcttagcaa tatgggagca ggttttcact gaattctgag ggtgcctctg catgtcctcc   4500

aaggcaaagt ttggcaaact gtggcccccc cactgtcata ttttgttaat aaaattttat   4560

tggaacacaa tcaca                                                    4575


<210>  6671
<211>  1304
<212>  PRT
<213>  Homo sapiens

<400>  6671

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu 
                245                 250                 255


Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro 
            260                 265                 270


Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu 
        275                 280                 285


Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe 
    290                 295                 300


Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly 
305                 310                 315                 320


Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu 
                325                 330                 335


Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala 
            340                 345                 350


Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro 
        355                 360                 365


Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala 
    370                 375                 380


Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr 
385                 390                 395                 400


Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp 
                405                 410                 415


Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys 
            420                 425                 430


Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp 
        435                 440                 445


Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala 
    450                 455                 460


Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val 
465                 470                 475                 480


Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr 
                485                 490                 495


Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser 
            500                 505                 510


Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys 
        515                 520                 525


Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn 
    530                 535                 540


Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala 
545                 550                 555                 560


Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala 
                565                 570                 575


Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro 
            580                 585                 590


Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro 
        595                 600                 605


Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys 
    610                 615                 620


Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala 
625                 630                 635                 640


Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp 
                645                 650                 655


Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val 
            660                 665                 670


Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu 
        675                 680                 685


Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser 
    690                 695                 700


Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg 
705                 710                 715                 720


Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala 
                725                 730                 735


Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp 
            740                 745                 750


Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp 
        755                 760                 765


Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln 
    770                 775                 780


Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr 
785                 790                 795                 800


Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys 
                805                 810                 815


Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys 
            820                 825                 830


Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp 
        835                 840                 845


Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys 
    850                 855                 860


Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys 
865                 870                 875                 880


His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro 
                885                 890                 895


Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu 
            900                 905                 910


Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro 
        915                 920                 925


Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro 
    930                 935                 940


Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His 
945                 950                 955                 960


Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val 
                965                 970                 975


Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys 
            980                 985                 990


Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala 
        995                 1000                1005


Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val 
    1010                1015                1020


Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn 
1025                1030                1035                1040


Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu 
                1045                1050                1055


Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro 
            1060                1065                1070


Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly 
        1075                1080                1085


Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly 
    1090                1095                1100


Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn 
1105                1110                1115                1120


Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro 
                1125                1130                1135


Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys 
            1140                1145                1150


Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu 
        1155                1160                1165


Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser 
    1170                1175                1180


Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp 
1185                1190                1195                1200


Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu 
                1205                1210                1215


Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile 
            1220                1225                1230


Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val 
        1235                1240                1245


Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr 
    1250                1255                1260


Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala 
1265                1270                1275                1280


Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp 
                1285                1290                1295


Pro Leu Asn Ala Phe Gly Gly Gln 
            1300


<210>  6672
<211>  4627
<212>  DNA
<213>  Homo sapiens

<400>  6672
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggaggaccag   1860

tggaatattc ctgcttcaca gacccactta gcatctgaca gcaggtctaa aggagaaccc   1920

agggattctg ggaccctcca gagccaggag gccaaggctg tgaaaaagac cagtctcttt   1980

gaggaagaca aagaagatga tctttttgcc attgccaagg acagatacat cctacctcct   2040

attgttcccg aagttgtctg tcaagttttg tgtatggaaa gtaattcata ccttcatcag   2100

atctcaaaag aagctttaca cacacaagaa gaagttgagc caaaagaaga cccagagagt   2160

gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac   2220

atctgttcct cctgcaacaa agaaaaaaga gactgtctct gaggcaccac ctttgctgtt   2280

cagcgatgaa gaagagaagg aggcacaact tggagtgaag tctgtggata agaaggttga   2340

gagtgccaag gagtcattaa aatttgggag aactgatgtg gctgagtcag aaaaggaagg   2400

acttttgact agatctgctc aggaaacagt caagcattct gatttatttt cttcatcatc   2460

cccatgggac aaaggaacca agcctagaac caaaactgtt cttagcttgt ttgatgagga   2520

agaggataaa atggaagatc aaaacattat ccaggctcca cagaaagaag taggaaaggg   2580

ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc caggatgaag agctgctttt   2640

cagccacaag ctccaaaagg acaatgaccc agatgttgac ctttttgctg gcaccaaaaa   2700

aaccaagctg ttagagccaa gtgttgggag cctgtttggg gatgatgaag atgatgatct   2760

tttcagctct gccaagtccc agcctttggt acaagagaaa aagagagtag tgaaaaaaga   2820

ccactctgtt aactctttca aaaaccagaa acatcctgaa tccattcaag gtagtaaaga   2880

aaaaggcata tggaagccgg aaacacctca ggcaaattta gcgatcaacc cagcggcctt   2940

gctgcccaca gcggcttccc agatctctga agtaaagcct gttttgccag aattggcttt   3000

tccttcatct gaacacagaa ggagccacgg tctggaaagt gtgcctgtcc ttcccgggag   3060

tggggaggcc ggtgtgagtt ttgatcttcc agctcaggca gacaccttac acagtgcaaa   3120

caagagccgt gtcaagatga gagggaagcg tagaccgcag acccgtgcag ctaggcggct   3180

ggctgctcag gagtccagcg aggctgagga catgagcgtc cccagaggac ccattgcaca   3240

gtgggctgat ggcgccattt ccccaaatgg ccatcggcca cagctcagag cagccagtgg   3300

agaagacagc actgaggagg ccctggcagc tgccgctgca ccttgggaag gtggtcctgt   3360

gcctggagtg gacacaagcc cctttgcaaa gtctctgggt cattccagag gggaggctga   3420

cctttttgat tctggggaca ttttttccac gggcactgga tctcagtccg tggagagaac   3480

aaaacccaag gcaaagatag cagagaatcc tgccaaccca ccagtgggtg gtaaagcaaa   3540

gagccccatg tttcctgctc taggcgaggc cagcagtgat gatgatctct ttcagtctgc   3600

taaaccaaaa ccagcaaaga aaacaaatcc ctttcctctc ctggaagatg aggatgacct   3660

ctttacagat cagaaagtca agaagaatga gacaaaatcc agtagtcagc aggatgtcat   3720

attaacaaca caagatattt ttgaggatga tatatttgct acggaagcaa ttaaaccctc   3780

tcagaaaacc agagagaagg agaaaacatt ggaatctaat ttatttgatg ataacattga   3840

tatctttgct gacttaactg taaaaccaaa agaaaagtcc aaaaagaaag tggaagccaa   3900

gtctatattt gatgatgata tggatgacat cttctccact ggtatccagg ctaagacaac   3960

caaaccaaaa agccgatctg cacaggccgc acctgaacca agatttgaac acaaggtgtc   4020

caacatcttt gatgatcccc tgaatgcctt tggaggccag tagagcacac agggtatcca   4080

catgttaccc tgcagctaca ttgttgagtt agtgatgata ttgtatatgc tcatggtctt   4140

aactggatta caaaaagcaa atactagaac agctagctca tcttttaccc aatgtactta   4200

gtatttttct gcactggttt aatcatgctt aatactacaa aacaaaaata aatatttcac   4260

agtggttggt ttgttttgtt tttaaaccac agtttgattt agttagcctt gctggggcca   4320

taatatgctt cagggtgtgt aaaagaagaa atctctttgt ggctttcatg ggcagggaat   4380

ctcagagata gcaaatgcca cctgaccaga agtctttgtt atatggatgg gaaccctaac   4440

ttagggcttg ggcaggggaa agagaaagaa gatgagagat tatacttcat gagtcttagc   4500

aatatgggag caggttttca ctgaattctg agggtgcctc tgcatgtcct ccaaggcaaa   4560

gtttggcaaa ctgtggcccc cccactgtca tattttgtta ataaaatttt attggaacac   4620

aatcaca                                                             4627


<210>  6673
<211>  692
<212>  PRT
<213>  Homo sapiens

<400>  6673

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu 
                245                 250                 255


Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro 
            260                 265                 270


Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu 
        275                 280                 285


Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe 
    290                 295                 300


Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly 
305                 310                 315                 320


Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu 
                325                 330                 335


Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala 
            340                 345                 350


Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro 
        355                 360                 365


Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala 
    370                 375                 380


Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr 
385                 390                 395                 400


Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp 
                405                 410                 415


Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys 
            420                 425                 430


Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp 
        435                 440                 445


Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala 
    450                 455                 460


Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val 
465                 470                 475                 480


Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr 
                485                 490                 495


Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser 
            500                 505                 510


Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys 
        515                 520                 525


Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn 
    530                 535                 540


Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala 
545                 550                 555                 560


Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala 
                565                 570                 575


Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro 
            580                 585                 590


Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro 
        595                 600                 605


Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys 
    610                 615                 620


Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala 
625                 630                 635                 640


Lys Asp Arg Tyr Ile Leu Pro Pro Ile Val Pro Glu Val Val Cys Gln 
                645                 650                 655


Val Leu Cys Met Glu Ser Asn Ser Tyr Leu His Gln Ile Ser Lys Glu 
            660                 665                 670


Ala Leu His Thr Gln Glu Glu Val Glu Pro Lys Glu Asp Pro Glu Ser 
        675                 680                 685


Val Thr Pro Leu 
    690


<210>  6674
<211>  4414
<212>  DNA
<213>  Homo sapiens

<400>  6674
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagc caaaagaaga cccagagagt   2100

gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct ctcctcccac   2160

atctgttcct cctgcaacaa aggaaggact tttgactaga tctgctcagg aaacagtcaa   2220

gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc ctagaaccaa   2280

aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa acattatcca   2340

ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca agagcacagg   2400

tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca atgacccaga   2460

tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg ttgggagcct   2520

gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc ctttggtaca   2580

agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa accagaaaca   2640

tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa cacctcaggc   2700

aaatttagcg atcaacccag cggccttgct gcccacagcg gcttcccaga tctctgaagt   2760

aaagcctgtt ttgccagaat tggcttttcc ttcatctgaa cacagaagga gccacggtct   2820

ggaaagtgtg cctgtccttc ccgggagtgg ggaggccggt gtgagttttg atcttccagc   2880

tcaggcagac accttacaca gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag   2940

accgcagacc cgtgcagcta ggcggctggc tgctcaggag tccagcgagg ctgaggacat   3000

gagcgtcccc agaggaccca ttgcacagtg ggctgatggc gccatttccc caaatggcca   3060

tcggccacag ctcagagcag ccagtggaga agacagcact gaggaggccc tggcagctgc   3120

cgctgcacct tgggaaggtg gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc   3180

tctgggtcat tccagagggg aggctgacct ttttgattct ggggacattt tttccacggg   3240

cactggatct cagtccgtgg agagaacaaa acccaaggca aagatagcag agaatcctgc   3300

caacccacca gtgggtggta aagcaaagag ccccatgttt cctgctctag gcgaggccag   3360

cagtgatgat gatctctttc agtctgctaa accaaaacca gcaaagaaaa caaatccctt   3420

tcctctcctg gaagatgagg atgacctctt tacagatcag aaagtcaaga agaatgagac   3480

aaaatccagt agtcagcagg atgtcatatt aacaacacaa gatatttttg aggatgatat   3540

atttgctacg gaagcaatta aaccctctca gaaaaccaga gagaaggaga aaacattgga   3600

atctaattta tttgatgata acattgatat ctttgctgac ttaactgtaa aaccaaaaga   3660

aaagtccaaa aagaaagtgg aagccaagtc tatatttgat gatgatatgg atgacatctt   3720

ctccactggt atccaggcta agacaaccaa accaaaaagc cgatctgcac aggccgcacc   3780

tgaaccaaga tttgaacaca aggtgtccaa catctttgat gatcccctga atgcctttgg   3840

aggccagtag agcacacagg gtatccacat gttaccctgc agctacattg ttgagttagt   3900

gatgatattg tatatgctca tggtcttaac tggattacaa aaagcaaata ctagaacagc   3960

tagctcatct tttacccaat gtacttagta tttttctgca ctggtttaat catgcttaat   4020

actacaaaac aaaaataaat atttcacagt ggttggtttg ttttgttttt aaaccacagt   4080

ttgatttagt tagccttgct ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc   4140

tctttgtggc tttcatgggc agggaatctc agagatagca aatgccacct gaccagaagt   4200

ctttgttata tggatgggaa ccctaactta gggcttgggc aggggaaaga gaaagaagat   4260

gagagattat acttcatgag tcttagcaat atgggagcag gttttcactg aattctgagg   4320

gtgcctctgc atgtcctcca aggcaaagtt tggcaaactg tggccccccc actgtcatat   4380

tttgttaata aaattttatt ggaacacaat caca                               4414


<210>  6675
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6675

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6676
<211>  4686
<212>  DNA
<213>  Homo sapiens

<400>  6676
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggttacc ttatcttaca gcaaaaatct caagccctca   1680

tcagaaacaa agactcaaaa aggcttattt tcagatgagg aggactctga ggatttgttt   1740

tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc tgcctggcaa gctccccacg   1800

tcggtttccc tgtttgatga tgaagatgaa gaggataatc tttttggggg tacagctgct   1860

aagaagcaga cattgtctct acaagctcag agagaagaga aagcaaaagc ctccgagctc   1920

tccaaaaaga aagcatctgc cctgttgttc agcagtgatg aggaggacca gtggaatatt   1980

cctgcttcac agacccactt agcatctgac agcaggtcta aaggagaacc cagggattct   2040

gggaccctcc agagccagga ggccaaggct gtgaaaaaga ccagtctctt tgaggaagac   2100

aaagaagatg atctttttgc cattgccaag gacagccaaa agaagaccca gagagtgtca   2160

ctcctctttg aagacgatgt tgatagcgga ggctctctgt ttggctctcc tcccacatct   2220

gttcctcctg caacaaagaa aaaagagact gtctctgagg caccaccttt gctgttcagc   2280

gatgaagaag agaaggaggc acaacttgga gtgaagtctg tggataagaa ggttgagagt   2340

gccaaggagt cattaaaatt tgggagaact gatgtggctg agtcagaaaa ggaaggactt   2400

ttgactagat ctgctcagga aacagtcaag cattctgatt tattttcttc atcatcccca   2460

tgggacaaag gaaccaagcc tagaaccaaa actgttctta gcttgtttga tgaggaagag   2520

gataaaatgg aagatcaaaa cattatccag gctccacaga aagaagtagg aaagggctgc   2580

gatcctgatg cccaccccaa gagcacaggt gtcttccagg atgaagagct gcttttcagc   2640

cacaagctcc aaaaggacaa tgacccagat gttgaccttt ttgctggcac caaaaaaacc   2700

aagctgttag agccaagtgt tgggagcctg tttggggatg atgaagatga tgatcttttc   2760

agctctgcca agtcccagcc tttggtacaa gagaaaaaga gagtagtgaa aaaagaccac   2820

tctgttaact ctttcaaaaa ccagaaacat cctgaatcca ttcaaggtag taaagaaaaa   2880

ggcatatgga agccggaaac acctcaggac tcatcaggtc tcgctccatt taaaaccaaa   2940

gaaccatcca ctcggatcgg gaagatacaa gcaaatttag cgatcaaccc agcggccttg   3000

ctgcccacag cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt   3060

ccttcatctg aacacagaag gagccacggt ctggaaagtg tgcctgtcct tcccgggagt   3120

ggggaggccg gtgtgagttt tgatcttcca gctcaggcag acaccttaca cagtgcaaac   3180

aagagccgtg tcaagatgag agggaagcgt agaccgcaga cccgtgcagc taggcggctg   3240

gctgctcagg agtccagcga ggctgaggac atgagcgtcc ccagaggacc cattgcacag   3300

tgggctgatg gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga   3360

gaagacagca ctgaggaggc cctggcagct gccgctgcac cttgggaagg tggtcctgtg   3420

cctggagtgg acacaagccc ctttgcaaag tctctgggtc attccagagg ggaggctgac   3480

ctttttgatt ctggggacat tttttccacg ggcactggat ctcagtccgt ggagagaaca   3540

aaacccaagg caaagatagc agagaatcct gccaacccac cagtgggtgg taaagcaaag   3600

agccccatgt ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct   3660

aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc tggaagatga ggatgacctc   3720

tttacagatc agaaagtcaa gaagaatgag acaaaatcca gtagtcagca ggatgtcata   3780

ttaacaacac aagatatttt tgaggatgat atatttgcta cggaagcaat taaaccctct   3840

cagaaaacca gagagaagga gaaaacattg gaatctaatt tatttgatga taacattgat   3900

atctttgctg acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag   3960

tctatatttg atgatgatat ggatgacatc ttctccactg gtatccaggc taagacaacc   4020

aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa gatttgaaca caaggtgtcc   4080

aacatctttg atgatcccct gaatgccttt ggaggccagt agagcacaca gggtatccac   4140

atgttaccct gcagctacat tgttgagtta gtgatgatat tgtatatgct catggtctta   4200

actggattac aaaaagcaaa tactagaaca gctagctcat cttttaccca atgtacttag   4260

tatttttctg cactggttta atcatgctta atactacaaa acaaaaataa atatttcaca   4320

gtggttggtt tgttttgttt ttaaaccaca gtttgattta gttagccttg ctggggccat   4380

aatatgcttc agggtgtgta aaagaagaaa tctctttgtg gctttcatgg gcagggaatc   4440

tcagagatag caaatgccac ctgaccagaa gtctttgtta tatggatggg aaccctaact   4500

tagggcttgg gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca   4560

atatgggagc aggttttcac tgaattctga gggtgcctct gcatgtcctc caaggcaaag   4620

tttggcaaac tgtggccccc ccactgtcat attttgttaa taaaatttta ttggaacaca   4680

atcaca                                                              4686


<210>  6677
<211>  1341
<212>  PRT
<213>  Homo sapiens

<400>  6677

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser 
        515                 520                 525


Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser 
    530                 535                 540


Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser 
545                 550                 555                 560


Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu 
                565                 570                 575


Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr 
            580                 585                 590


Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu 
        595                 600                 605


Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp 
    610                 615                 620


Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg 
625                 630                 635                 640


Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala 
                645                 650                 655


Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp 
            660                 665                 670


Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser 
        675                 680                 685


Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser 
    690                 695                 700


Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser 
705                 710                 715                 720


Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln 
                725                 730                 735


Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser 
            740                 745                 750


Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu 
        755                 760                 765


Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser 
    770                 775                 780


Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val 
785                 790                 795                 800


Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile 
                805                 810                 815


Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala 
            820                 825                 830


His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser 
        835                 840                 845


His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly 
    850                 855                 860


Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly 
865                 870                 875                 880


Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu 
                885                 890                 895


Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser 
            900                 905                 910


Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys 
        915                 920                 925


Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro 
    930                 935                 940


Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn 
945                 950                 955                 960


Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile 
                965                 970                 975


Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu 
            980                 985                 990


His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser 
        995                 1000                1005


Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu 
    1010                1015                1020


His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro 
1025                1030                1035                1040


Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala 
                1045                1050                1055


Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly 
            1060                1065                1070


Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly 
        1075                1080                1085


Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu 
    1090                1095                1100


Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu 
1105                1110                1115                1120


Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe 
                1125                1130                1135


Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala 
            1140                1145                1150


Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys 
        1155                1160                1165


Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu 
    1170                1175                1180


Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro 
1185                1190                1195                1200


Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys 
                1205                1210                1215


Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln 
            1220                1225                1230


Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser 
        1235                1240                1245


Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp 
    1250                1255                1260


Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys 
1265                1270                1275                1280


Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp 
                1285                1290                1295


Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser 
            1300                1305                1310


Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser 
        1315                1320                1325


Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
    1330                1335                1340


<210>  6678
<211>  4852
<212>  DNA
<213>  Homo sapiens

<400>  6678
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaagagtttc actcttgttg cccaagctgg agtggcgcaa    660

tctcggctca ctgcagcttc tgtctcctgg gttcaagcga ttctcctgcc tcagccttcc    720

aagtagctgg gattacagga tctatacatt gatcgtcctt taccatatct cattgggtca    780

aagctgttca tggaacaaga agatgtaggt cttggagagc tgtccagtga agaaggctct    840

gtaggcagtg atcgtggcag tattgtggac actgaggaag agaaagaaga ggaggagtca    900

gatgaagatt ttgcccatca cagtgacaat gaacaaaacc agcacaccac acaaatgagt    960

gatgaggaag aggatgatga tggctgtgac ctttttgctg actctgagaa ggaggaggaa   1020

gatattgagg acattgaaga aaatactaga cctaaaagaa gcagacctac atcgtttgca   1080

gatgagctgg ctgcccgcat caagggggat gccatgggtc gagtggacga ggagccgaca   1140

accttaccct caggagaagc aaaacctcgg aagacactca aagagaagaa ggaaaggaga   1200

actccttcag acgatgaaga ggataactta ttcgcacccc ccaagctgac cgacgaggac   1260

ttctcgccat ttggctctgg aggtggcctg ttcagtggcg gcaaggggct atttgatgat   1320

gaggacgagg agagtgacct cttcacggaa gcctcccagg atcggcaagc tggagcctct   1380

gttaaggagg agtcttcatc atccaaacct ggaaagaaaa tcccagcagg agctgtttct   1440

gtatttttag gagacacgga tgtgtttggt gctgcctccg ttccatcact gaaggagcca   1500

cagaagcctg agcagcccac tccaaggaaa agcccctatg gtccccctcc cactggcctc   1560

tttgatgatg atgatggtga tgatgatgac gactttttct cggcacccca cagcaaacct   1620

tctaaaacac gcaaagtcca atccactgcc gatatctttg gtgacgaaga aggagatctg   1680

ttcaaagaaa aagccgtagc atcgccagaa gccactgtga gtcagacaga tgaaaataaa   1740

gcaagagcag aaaaaaaggt taccttatct tacagcaaaa atctcaagcc ctcatcagaa   1800

acaaagactc aaaaaggctt attttcagat gaggaggact ctgaggattt gttttcttct   1860

caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg gcaagctccc cacgtcggtt   1920

tccctgtttg atgatgaaga tgaagaggat aatctttttg ggggtacagc tgctaagaag   1980

cagacattgt ctctacaagc tcagagagaa gagaaagcaa aagcctccga gctctccaaa   2040

aagaaagcat ctgccctgtt gttcagcagt gatgaggagg accagtggaa tattcctgct   2100

tcacagaccc acttagcatc tgacagcagg tctaaaggag aacccaggga ttctgggacc   2160

ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc tctttgagga agacaaagaa   2220

gatgatcttt ttgccattgc caaggacaga tacatcctac ctcctattgt tcccgaagtt   2280

gtctgtcaag ttttgtgtat ggaaagtaat tcataccttc atcagatctc aaaagaagct   2340

ttacacacac aagaagaagt tgagccaaaa gaagacccag agagtgtcac tcctctttga   2400

agacgatgtt gatagcggag gctctctgtt tggctctcct cccacatctg ttcctcctgc   2460

aacaaagaaa aaagagactg tctctgaggc accacctttg ctgttcagcg atgaagaaga   2520

gaaggaggca caacttggag tgaagtctgt ggataagaag gttgagagtg ccaaggagtc   2580

attaaaattt gggagaactg atgtggctga gtcagaaaag gaaggacttt tgactagatc   2640

tgctcaggaa acagtcaagc attctgattt attttcttca tcatccccat gggacaaagg   2700

aaccaagcct agaaccaaaa ctgttcttag cttgtttgat gaggaagagg ataaaatgga   2760

agatcaaaac attatccagg ctccacagaa agaagtagga aagggctgcg atcctgatgc   2820

ccaccccaag agcacaggtg tcttccagga tgaagagctg cttttcagcc acaagctcca   2880

aaaggacaat gacccagatg ttgacctttt tgctggcacc aaaaaaacca agctgttaga   2940

gccaagtgtt gggagcctgt ttggggatga tgaagatgat gatcttttca gctctgccaa   3000

gtcccagcct ttggtacaag agaaaaagag agtagtgaaa aaagaccact ctgttaactc   3060

tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt aaagaaaaag gcatatggaa   3120

gccggaaaca cctcaggcaa atttagcgat caacccagcg gccttgctgc ccacagcggc   3180

ttcccagatc tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca   3240

cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt   3300

gagttttgat cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa   3360

gatgagaggg aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc   3420

cagcgaggct gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc   3480

catttcccca aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga   3540

ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacac   3600

aagccccttt gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg   3660

ggacattttt tccacgggca ctggatctca gtccgtggag agaacaaaac ccaaggcaaa   3720

gatagcagag aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc   3780

tgctctaggc gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc   3840

aaagaaaaca aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa   3900

agtcaagaag aatgagacaa aatccagtag tcagcaggat gtcatattaa caacacaaga   3960

tatttttgag gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga   4020

gaaggagaaa acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt   4080

aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga   4140

tgatatggat gacatcttct ccactggtat ccaggctaag acaaccaaac caaaaagccg   4200

atctgcacag gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga   4260

tcccctgaat gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag   4320

ctacattgtt gagttagtga tgatattgta tatgctcatg gtcttaactg gattacaaaa   4380

agcaaatact agaacagcta gctcatcttt tacccaatgt acttagtatt tttctgcact   4440

ggtttaatca tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt   4500

ttgtttttaa accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg   4560

tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag ggaatctcag agatagcaaa   4620

tgccacctga ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcttgggcag   4680

gggaaagaga aagaagatga gagattatac ttcatgagtc ttagcaatat gggagcaggt   4740

tttcactgaa ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg   4800

gcccccccac tgtcatattt tgttaataaa attttattgg aacacaatca ca           4852


<210>  6679
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6679

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6680
<211>  4738
<212>  DNA
<213>  Homo sapiens

<400>  6680
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggttacc ttatcttaca gcaaaaatct caagccctca   1680

tcagaaacaa agactcaaaa aggcttattt tcagatgagg aggactctga ggatttgttt   1740

tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc tgcctggcaa gctccccacg   1800

tcggtttccc tgtttgatga tgaagatgaa gaggataatc tttttggggg tacagctgct   1860

aagaagcaga cattgtctct acaagctcag agagaagaga aagcaaaagc ctccgagctc   1920

tccaaaaaga aagcatctgc cctgttgttc agcagtgatg aggaggacca gtggaatatt   1980

cctgcttcac agacccactt agcatctgac agcaggtcta aaggagaacc cagggattct   2040

gggaccctcc agagccagga ggccaaggct gtgaaaaaga ccagtctctt tgaggaagac   2100

aaagaagatg atctttttgc cattgccaag gacagataca tcctacctcc tattgttccc   2160

gaagttgtct gtcaagtttt gtgtatggaa agtaattcat accttcatca gatctcaaaa   2220

gaagctttac acacacaaga agaagttgag ccaaaagaag acccagagag tgtcactcct   2280

ctttgaagac gatgttgata gcggaggctc tctgtttggc tctcctccca catctgttcc   2340

tcctgcaaca aagaaaaaag agactgtctc tgaggcacca cctttgctgt tcagcgatga   2400

agaagagaag gaggcacaac ttggagtgaa gtctgtggat aagaaggttg agagtgccaa   2460

ggagtcatta aaatttggga gaactgatgt ggctgagtca gaaaaggaag gacttttgac   2520

tagatctgct caggaaacag tcaagcattc tgatttattt tcttcatcat ccccatggga   2580

caaaggaacc aagcctagaa ccaaaactgt tcttagcttg tttgatgagg aagaggataa   2640

aatggaagat caaaacatta tccaggctcc acagaaagaa gtaggaaagg gctgcgatcc   2700

tgatgcccac cccaagagca caggtgtctt ccaggatgaa gagctgcttt tcagccacaa   2760

gctccaaaag gacaatgacc cagatgttga cctttttgct ggcaccaaaa aaaccaagct   2820

gttagagcca agtgttggga gcctgtttgg ggatgatgaa gatgatgatc ttttcagctc   2880

tgccaagtcc cagcctttgg tacaagagaa aaagagagta gtgaaaaaag accactctgt   2940

taactctttc aaaaaccaga aacatcctga atccattcaa ggtagtaaag aaaaaggcat   3000

atggaagccg gaaacacctc aggcaaattt agcgatcaac ccagcggcct tgctgcccac   3060

agcggcttcc cagatctctg aagtaaagcc tgttttgcca gaattggctt ttccttcatc   3120

tgaacacaga aggagccacg gtctggaaag tgtgcctgtc cttcccggga gtggggaggc   3180

cggtgtgagt tttgatcttc cagctcaggc agacacctta cacagtgcaa acaagagccg   3240

tgtcaagatg agagggaagc gtagaccgca gacccgtgca gctaggcggc tggctgctca   3300

ggagtccagc gaggctgagg acatgagcgt ccccagagga cccattgcac agtgggctga   3360

tggcgccatt tccccaaatg gccatcggcc acagctcaga gcagccagtg gagaagacag   3420

cactgaggag gccctggcag ctgccgctgc accttgggaa ggtggtcctg tgcctggagt   3480

ggacacaagc ccctttgcaa agtctctggg tcattccaga ggggaggctg acctttttga   3540

ttctggggac attttttcca cgggcactgg atctcagtcc gtggagagaa caaaacccaa   3600

ggcaaagata gcagagaatc ctgccaaccc accagtgggt ggtaaagcaa agagccccat   3660

gtttcctgct ctaggcgagg ccagcagtga tgatgatctc tttcagtctg ctaaaccaaa   3720

accagcaaag aaaacaaatc cctttcctct cctggaagat gaggatgacc tctttacaga   3780

tcagaaagtc aagaagaatg agacaaaatc cagtagtcag caggatgtca tattaacaac   3840

acaagatatt tttgaggatg atatatttgc tacggaagca attaaaccct ctcagaaaac   3900

cagagagaag gagaaaacat tggaatctaa tttatttgat gataacattg atatctttgc   3960

tgacttaact gtaaaaccaa aagaaaagtc caaaaagaaa gtggaagcca agtctatatt   4020

tgatgatgat atggatgaca tcttctccac tggtatccag gctaagacaa ccaaaccaaa   4080

aagccgatct gcacaggccg cacctgaacc aagatttgaa cacaaggtgt ccaacatctt   4140

tgatgatccc ctgaatgcct ttggaggcca gtagagcaca cagggtatcc acatgttacc   4200

ctgcagctac attgttgagt tagtgatgat attgtatatg ctcatggtct taactggatt   4260

acaaaaagca aatactagaa cagctagctc atcttttacc caatgtactt agtatttttc   4320

tgcactggtt taatcatgct taatactaca aaacaaaaat aaatatttca cagtggttgg   4380

tttgttttgt ttttaaacca cagtttgatt tagttagcct tgctggggcc ataatatgct   4440

tcagggtgtg taaaagaaga aatctctttg tggctttcat gggcagggaa tctcagagat   4500

agcaaatgcc acctgaccag aagtctttgt tatatggatg ggaaccctaa cttagggctt   4560

gggcagggga aagagaaaga agatgagaga ttatacttca tgagtcttag caatatggga   4620

gcaggttttc actgaattct gagggtgcct ctgcatgtcc tccaaggcaa agtttggcaa   4680

actgtggccc ccccactgtc atattttgtt aataaaattt tattggaaca caatcaca     4738


<210>  6681
<211>  729
<212>  PRT
<213>  Homo sapiens

<400>  6681

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser 
        515                 520                 525


Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser 
    530                 535                 540


Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser 
545                 550                 555                 560


Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu 
                565                 570                 575


Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr 
            580                 585                 590


Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu 
        595                 600                 605


Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp 
    610                 615                 620


Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg 
625                 630                 635                 640


Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala 
                645                 650                 655


Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp 
            660                 665                 670


Leu Phe Ala Ile Ala Lys Asp Arg Tyr Ile Leu Pro Pro Ile Val Pro 
        675                 680                 685


Glu Val Val Cys Gln Val Leu Cys Met Glu Ser Asn Ser Tyr Leu His 
    690                 695                 700


Gln Ile Ser Lys Glu Ala Leu His Thr Gln Glu Glu Val Glu Pro Lys 
705                 710                 715                 720


Glu Asp Pro Glu Ser Val Thr Pro Leu 
                725


<210>  6682
<211>  4714
<212>  DNA
<213>  Homo sapiens

<400>  6682
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggatttg ttttcttctc aaagtgcgag taacttaaaa   1680

ggtgcatctc tgctgcctgg caagctcccc acgtcggttt ccctgtttga tgatgaagat   1740

gaagaggata atctttttgg gggtacagct gctaagaagc agacattgtc tctacaagct   1800

cagagagaag agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg   1860

ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca cttagcatct   1920

gacagcaggt ctaaaggaga acccagggat tctgggaccc tccagagcca ggaggccaag   1980

gctgtgaaaa agaccagtct ctttgaggaa gacaaagaag atgatctttt tgccattgcc   2040

aaggacagat acatcctacc tcctattgtt cccgaagttg tctgtcaagt tttgtgtatg   2100

gaaagtaatt cataccttca tcagatctca aaagaagctt tacacacaca agaagaagtt   2160

gagccaaaag aagacccaga gagtgtcact cctctttgaa gacgatgttg atagcggagg   2220

ctctctgttt ggctctcctc ccacatctgt tcctcctgca acaaagaaaa aagagactgt   2280

ctctgaggca ccacctttgc tgttcagcga tgaagaagag aaggaggcac aacttggagt   2340

gaagtctgtg gataagaagg ttgagagtgc caaggagtca ttaaaatttg ggagaactga   2400

tgtggctgag tcagaaaagg aaggactttt gactagatct gctcaggaaa cagtcaagca   2460

ttctgattta ttttcttcat catccccatg ggacaaagga accaagccta gaaccaaaac   2520

tgttcttagc ttgtttgatg aggaagagga taaaatggaa gatcaaaaca ttatccaggc   2580

tccacagaaa gaagtaggaa agggctgcga tcctgatgcc caccccaaga gcacaggtgt   2640

cttccaggat gaagagctgc ttttcagcca caagctccaa aaggacaatg acccagatgt   2700

tgaccttttt gctggcacca aaaaaaccaa gctgttagag ccaagtgttg ggagcctgtt   2760

tggggatgat gaagatgatg atcttttcag ctctgccaag tcccagcctt tggtacaaga   2820

gaaaaagaga gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc agaaacatcc   2880

tgaatccatt caaggtagta aagaaaaagg catatggaag ccggaaacac ctcaggactc   2940

atcaggtctc gctccattta aaaccaaaga accatccact cggatcggga agatacaagc   3000

aaatttagcg atcaacccag cggccttgct gcccacagcg gcttcccaga tctctgaagt   3060

aaagcctgtt ttgccagaat tggcttttcc ttcatctgaa cacagaagga gccacggtct   3120

ggaaagtgtg cctgtccttc ccgggagtgg ggaggccggt gtgagttttg atcttccagc   3180

tcaggcagac accttacaca gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag   3240

accgcagacc cgtgcagcta ggcggctggc tgctcaggag tccagcgagg ctgaggacat   3300

gagcgtcccc agaggaccca ttgcacagtg ggctgatggc gccatttccc caaatggcca   3360

tcggccacag ctcagagcag ccagtggaga agacagcact gaggaggccc tggcagctgc   3420

cgctgcacct tgggaaggtg gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc   3480

tctgggtcat tccagagggg aggctgacct ttttgattct ggggacattt tttccacggg   3540

cactggatct cagtccgtgg agagaacaaa acccaaggca aagatagcag agaatcctgc   3600

caacccacca gtgggtggta aagcaaagag ccccatgttt cctgctctag gcgaggccag   3660

cagtgatgat gatctctttc agtctgctaa accaaaacca gcaaagaaaa caaatccctt   3720

tcctctcctg gaagatgagg atgacctctt tacagatcag aaagtcaaga agaatgagac   3780

aaaatccagt agtcagcagg atgtcatatt aacaacacaa gatatttttg aggatgatat   3840

atttgctacg gaagcaatta aaccctctca gaaaaccaga gagaaggaga aaacattgga   3900

atctaattta tttgatgata acattgatat ctttgctgac ttaactgtaa aaccaaaaga   3960

aaagtccaaa aagaaagtgg aagccaagtc tatatttgat gatgatatgg atgacatctt   4020

ctccactggt atccaggcta agacaaccaa accaaaaagc cgatctgcac aggccgcacc   4080

tgaaccaaga tttgaacaca aggtgtccaa catctttgat gatcccctga atgcctttgg   4140

aggccagtag agcacacagg gtatccacat gttaccctgc agctacattg ttgagttagt   4200

gatgatattg tatatgctca tggtcttaac tggattacaa aaagcaaata ctagaacagc   4260

tagctcatct tttacccaat gtacttagta tttttctgca ctggtttaat catgcttaat   4320

actacaaaac aaaaataaat atttcacagt ggttggtttg ttttgttttt aaaccacagt   4380

ttgatttagt tagccttgct ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc   4440

tctttgtggc tttcatgggc agggaatctc agagatagca aatgccacct gaccagaagt   4500

ctttgttata tggatgggaa ccctaactta gggcttgggc aggggaaaga gaaagaagat   4560

gagagattat acttcatgag tcttagcaat atgggagcag gttttcactg aattctgagg   4620

gtgcctctgc atgtcctcca aggcaaagtt tggcaaactg tggccccccc actgtcatat   4680

tttgttaata aaattttatt ggaacacaat caca                               4714


<210>  6683
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6683

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6684
<211>  4189
<212>  DNA
<213>  Homo sapiens

<400>  6684
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagaa aagaagcaga    840

cctacatcgt ttgcagatga gctggctgcc cgcatcaagg gggatgccat gggtcgagtg    900

gacgaggagc cgacaacctt accctcagga gaagcaaaac ctcggaagac actcaaagag    960

aagaaggaaa ggagaactcc ttcagacgat gaagaggata acttattcgc accccccaag   1020

ctgaccgacg aggacttctc gccatttggc tctggaggtg gcctgttcag tggcggcaag   1080

gggctatttg atgatgagga cgaggagagt gacctcttca cggaagcctc ccaggatcgg   1140

caagctggag cctctgttaa ggaggagtct tcatcatcca aacctggaaa gaaaatccca   1200

gcaggagctg tttctgtatt tttaggagac acggatgtgt ttggtgctgc ctccgttcca   1260

tcactgaagg agccacagaa gcctgagcag cccactccaa ggaaaagccc ctatggtccc   1320

cctcccactg gcctctttga tgatgatgat ggtgatgatg atgacgactt tttctcggca   1380

ccccacagca aaccttctaa aacacgcaaa gtccaatcca ctgccgatat ctttggtgac   1440

gaagaaggag atctgttcaa agaaaaagcc gtagcatcgc cagaagccac tgtgagtcag   1500

acagatgaaa ataaagcaag agcagaaaaa aaggttacct tatcttacag caaaaatctc   1560

aagccctcat cagaaacaaa gactcaaaaa ggcttatttt cagatgagga ggactctgag   1620

gatttgtttt cttctcaaag tgcgagtaac ttaaaaggtg catctctgct gcctggcaag   1680

ctccccacgt cggtttccct gtttgatgat gaagatgaag aggataatct ttttgggggt   1740

acagctgcta agaagcagac attgtctcta caagctcaga gagaagagaa agcaaaagcc   1800

tccgagctct ccaaaaagaa agcatctgcc ctgttgttca gcagtgatga ggagccaaaa   1860

gaagacccag agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt   1920

tggctctcct cccacatctg ttcctcctgc aacaaaggaa ggacttttga ctagatctgc   1980

tcaggaaaca gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac   2040

caagcctaga accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga   2100

tcaaaacatt atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca   2160

ccccaagagc acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa   2220

ggacaatgac ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc   2280

aagtgttggg agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc   2340

ccagcctttg gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt   2400

caaaaaccag aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc   2460

ggaaacacct caggcaaatt tagcgatcaa cccagcggcc ttgctgccca cagcggcttc   2520

ccagatctct gaagtaaagc ctgttttgcc agaattggct tttccttcat ctgaacacag   2580

aaggagccac ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg ccggtgtgag   2640

ttttgatctt ccagctcagg cagacacctt acacagtgca aacaagagcc gtgtcaagat   2700

gagagggaag cgtagaccgc agacccgtgc agctaggcgg ctggctgctc aggagtccag   2760

cgaggctgag gacatgagcg tccccagagg acccattgca cagtgggctg atggcgccat   2820

ttccccaaat ggccatcggc cacagctcag agcagccagt ggagaagaca gcactgagga   2880

ggccctggca gctgccgctg caccttggga aggtggtcct gtgcctggag tggacacaag   2940

cccctttgca aagtctctgg gtcattccag aggggaggct gacctttttg attctgggga   3000

cattttttcc acgggcactg gatctcagtc cgtggagaga acaaaaccca aggcaaagat   3060

agcagagaat cctgccaacc caccagtggg tggtaaagca aagagcccca tgtttcctgc   3120

tctaggcgag gccagcagtg atgatgatct ctttcagtct gctaaaccaa aaccagcaaa   3180

gaaaacaaat ccctttcctc tcctggaaga tgaggatgac ctctttacag atcagaaagt   3240

caagaagaat gagacaaaat ccagtagtca gcaggatgtc atattaacaa cacaagatat   3300

ttttgaggat gatatatttg ctacggaagc aattaaaccc tctcagaaaa ccagagagaa   3360

ggagaaaaca ttggaatcta atttatttga tgataacatt gatatctttg ctgacttaac   3420

tgtaaaacca aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat ttgatgatga   3480

tatggatgac atcttctcca ctggtatcca ggctaagaca accaaaccaa aaagccgatc   3540

tgcacaggcc gcacctgaac caagatttga acacaaggtg tccaacatct ttgatgatcc   3600

cctgaatgcc tttggaggcc agtagagcac acagggtatc cacatgttac cctgcagcta   3660

cattgttgag ttagtgatga tattgtatat gctcatggtc ttaactggat tacaaaaagc   3720

aaatactaga acagctagct catcttttac ccaatgtact tagtattttt ctgcactggt   3780

ttaatcatgc ttaatactac aaaacaaaaa taaatatttc acagtggttg gtttgttttg   3840

tttttaaacc acagtttgat ttagttagcc ttgctggggc cataatatgc ttcagggtgt   3900

gtaaaagaag aaatctcttt gtggctttca tgggcaggga atctcagaga tagcaaatgc   3960

cacctgacca gaagtctttg ttatatggat gggaacccta acttagggct tgggcagggg   4020

aaagagaaag aagatgagag attatacttc atgagtctta gcaatatggg agcaggtttt   4080

cactgaattc tgagggtgcc tctgcatgtc ctccaaggca aagtttggca aactgtggcc   4140

cccccactgt catattttgt taataaaatt ttattggaac acaatcaca               4189


<210>  6685
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6685

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6686
<211>  4536
<212>  DNA
<213>  Homo sapiens

<400>  6686
acgccccggg cagcttggct ggggctaggc ttccggggct ctgcggtcct cggcctgtgc     60

tggcagcctc ggagcccacc gagccgggcg gctgggatga tgaaccggac gacccccgac    120

caggagctgg tgccggcgtc ggagcccgtg tgggagcggc cgtggtcggt ggaggagatc    180

cgcaggagca gccagagctg gtcgctggcg gccgacgcgg gcctactaca gtttctacag    240

gaattctcac agcaaactat ctctaggacc catgaaatca agaaacaagt ggacggacta    300

atccgggaaa ccaaagccac agattgtcgc ctgcataatg tcttcaatga cttccttatg    360

ctctctaata cccagttcat agagaatcgt gtatatgatg aagaagtgga ggagccagta    420

ctcaaggctg aggcagaaaa aacagagcag gagaagacac gagagcagaa agaagtagat    480

ctcattccta aagtccagga ggctgtgaac tatggcttac aagtattgga cagtgccttt    540

gagcaacttg atatcaaagc aggaaactca gactccgagg aagatgatgc taatgggcgg    600

gtggaactga tccttgaacc aaaggatcta tacattgatc gtcctttacc atatctcatt    660

gggtcaaagc tgttcatgga acaagaagat gtaggtcttg gagagctgtc cagtgaagaa    720

ggctctgtag gcagtgatcg tggcagtatt gtggacactg aggaagagaa agaagaggag    780

gagtcagatg aagattttgc ccatcacagt gacaatgaac aaaaccagca caccacacaa    840

atgagtgatg aggaagagga tgatgatggc tgtgaccttt ttgctgactc tgagaaggag    900

gaggaagata ttgaggacat tgaagaaaat actagaccta aaagaagcag acctacatcg    960

tttgcagatg agctggctgc ccgcatcaag ggggatgcca tgggtcgagt ggacgaggag   1020

ccgacaacct taccctcagg agaagcaaaa cctcggaaga cactcaaaga gaagaaggaa   1080

aggagaactc cttcagacga tgaagaggat aacttattcg caccccccaa gctgaccgac   1140

gaggacttct cgccatttgg ctctggaggt ggcctgttca gtggcggcaa ggggctattt   1200

gatgatgagg acgaggagag tgacctcttc acggaagcct cccaggatcg gcaagctgga   1260

gcctctgtta aggaggagtc ttcatcatcc aaacctggaa agaaaatccc agcaggagct   1320

gtttctgtat ttttaggaga cacggatgtg tttggtgctg cctccgttcc atcactgaag   1380

gagccacaga agcctgagca gcccactcca aggaaaagcc cctatggtcc ccctcccact   1440

ggcctctttg atgatgatga tggtgatgat gatgacgact ttttctcggc accccacagc   1500

aaaccttcta aaacacgcaa agtccaatcc actgccgata tctttggtga cgaagaagga   1560

gatctgttca aagaaaaagc cgtagcatcg ccagaagcca ctgtgagtca gacagatgaa   1620

aataaagcaa gagcagaaaa aaaggatttg ttttcttctc aaagtgcgag taacttaaaa   1680

ggtgcatctc tgctgcctgg caagctcccc acgtcggttt ccctgtttga tgatgaagat   1740

gaagaggata atctttttgg gggtacagct gctaagaagc agacattgtc tctacaagct   1800

cagagagaag agaaagcaaa agcctccgag ctctccaaaa agaaagcatc tgccctgttg   1860

ttcagcagtg atgaggagga ccagtggaat attcctgctt cacagaccca cttagcatct   1920

gacagcaggt ctaaaggaga acccagggat tctgggaccc tccagagcca ggaggccaag   1980

gctgtgaaaa agaccagtct ctttgaggaa gacaaagaag atgatctttt tgccattgcc   2040

aaggacagcc aaaagaagac ccagagagtg tcactcctct ttgaagacga tgttgatagc   2100

ggaggctctc tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag   2160

actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga ggcacaactt   2220

ggagtgaagt ctgtggataa gaaggttgag agtgccaagg agtcattaaa atttgggaga   2280

actgatgtgg ctgagtcaga aaaggaagga cttttgacta gatctgctca ggaaacagtc   2340

aagcattctg atttattttc ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc   2400

aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc   2460

caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc caagagcaca   2520

ggtgtcttcc aggatgaaga gctgcttttc agccacaagc tccaaaagga caatgaccca   2580

gatgttgacc tttttgctgg caccaaaaaa accaagctgt tagagccaag tgttgggagc   2640

ctgtttgggg atgatgaaga tgatgatctt ttcagctctg ccaagtccca gcctttggta   2700

caagagaaaa agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa   2760

catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga aacacctcag   2820

gcaaatttag cgatcaaccc agcggccttg ctgcccacag cggcttccca gatctctgaa   2880

gtaaagcctg ttttgccaga attggctttt ccttcatctg aacacagaag gagccacggt   2940

ctggaaagtg tgcctgtcct tcccgggagt ggggaggccg gtgtgagttt tgatcttcca   3000

gctcaggcag acaccttaca cagtgcaaac aagagccgtg tcaagatgag agggaagcgt   3060

agaccgcaga cccgtgcagc taggcggctg gctgctcagg agtccagcga ggctgaggac   3120

atgagcgtcc ccagaggacc cattgcacag tgggctgatg gcgccatttc cccaaatggc   3180

catcggccac agctcagagc agccagtgga gaagacagca ctgaggaggc cctggcagct   3240

gccgctgcac cttgggaagg tggtcctgtg cctggagtgg acacaagccc ctttgcaaag   3300

tctctgggtc attccagagg ggaggctgac ctttttgatt ctggggacat tttttccacg   3360

ggcactggat ctcagtccgt ggagagaaca aaacccaagg caaagatagc agagaatcct   3420

gccaacccac cagtgggtgg taaagcaaag agccccatgt ttcctgctct aggcgaggcc   3480

agcagtgatg atgatctctt tcagtctgct aaaccaaaac cagcaaagaa aacaaatccc   3540

tttcctctcc tggaagatga ggatgacctc tttacagatc agaaagtcaa gaagaatgag   3600

acaaaatcca gtagtcagca ggatgtcata ttaacaacac aagatatttt tgaggatgat   3660

atatttgcta cggaagcaat taaaccctct cagaaaacca gagagaagga gaaaacattg   3720

gaatctaatt tatttgatga taacattgat atctttgctg acttaactgt aaaaccaaaa   3780

gaaaagtcca aaaagaaagt ggaagccaag tctatatttg atgatgatat ggatgacatc   3840

ttctccactg gtatccaggc taagacaacc aaaccaaaaa gccgatctgc acaggccgca   3900

cctgaaccaa gatttgaaca caaggtgtcc aacatctttg atgatcccct gaatgccttt   3960

ggaggccagt agagcacaca gggtatccac atgttaccct gcagctacat tgttgagtta   4020

gtgatgatat tgtatatgct catggtctta actggattac aaaaagcaaa tactagaaca   4080

gctagctcat cttttaccca atgtacttag tatttttctg cactggttta atcatgctta   4140

atactacaaa acaaaaataa atatttcaca gtggttggtt tgttttgttt ttaaaccaca   4200

gtttgattta gttagccttg ctggggccat aatatgcttc agggtgtgta aaagaagaaa   4260

tctctttgtg gctttcatgg gcagggaatc tcagagatag caaatgccac ctgaccagaa   4320

gtctttgtta tatggatggg aaccctaact tagggcttgg gcaggggaaa gagaaagaag   4380

atgagagatt atacttcatg agtcttagca atatgggagc aggttttcac tgaattctga   4440

gggtgcctct gcatgtcctc caaggcaaag tttggcaaac tgtggccccc ccactgtcat   4500

attttgttaa taaaatttta ttggaacaca atcaca                             4536


<210>  6687
<211>  1291
<212>  PRT
<213>  Homo sapiens

<400>  6687

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Leu Leu Gln Phe Leu Gln 
        35                  40                  45


Glu Phe Ser Gln Gln Thr Ile Ser Arg Thr His Glu Ile Lys Lys Gln 
    50                  55                  60


Val Asp Gly Leu Ile Arg Glu Thr Lys Ala Thr Asp Cys Arg Leu His 
65                  70                  75                  80


Asn Val Phe Asn Asp Phe Leu Met Leu Ser Asn Thr Gln Phe Ile Glu 
                85                  90                  95


Asn Arg Val Tyr Asp Glu Glu Val Glu Glu Pro Val Leu Lys Ala Glu 
            100                 105                 110


Ala Glu Lys Thr Glu Gln Glu Lys Thr Arg Glu Gln Lys Glu Val Asp 
        115                 120                 125


Leu Ile Pro Lys Val Gln Glu Ala Val Asn Tyr Gly Leu Gln Val Leu 
    130                 135                 140


Asp Ser Ala Phe Glu Gln Leu Asp Ile Lys Ala Gly Asn Ser Asp Ser 
145                 150                 155                 160


Glu Glu Asp Asp Ala Asn Gly Arg Val Glu Leu Ile Leu Glu Pro Lys 
                165                 170                 175


Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr Leu Ile Gly Ser Lys Leu 
            180                 185                 190


Phe Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu 
        195                 200                 205


Gly Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu 
    210                 215                 220


Lys Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn 
225                 230                 235                 240


Glu Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp 
                245                 250                 255


Asp Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile 
            260                 265                 270


Glu Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser 
        275                 280                 285


Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg 
    290                 295                 300


Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg 
305                 310                 315                 320


Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu 
                325                 330                 335


Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser 
            340                 345                 350


Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe 
        355                 360                 365


Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp 
    370                 375                 380


Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro 
385                 390                 395                 400


Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr 
                405                 410                 415


Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys 
            420                 425                 430


Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr 
        435                 440                 445


Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser 
    450                 455                 460


Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala 
465                 470                 475                 480


Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val 
                485                 490                 495


Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg 
            500                 505                 510


Ala Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys 
        515                 520                 525


Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe 
    530                 535                 540


Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys 
545                 550                 555                 560


Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala 
                565                 570                 575


Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp 
            580                 585                 590


Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser 
        595                 600                 605


Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser 
    610                 615                 620


Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys 
625                 630                 635                 640


Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln 
                645                 650                 655


Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu 
            660                 665                 670


Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu 
        675                 680                 685


Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys 
    690                 695                 700


Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala 
705                 710                 715                 720


Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys 
                725                 730                 735


Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp 
            740                 745                 750


Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr 
        755                 760                 765


Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp 
    770                 775                 780


Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp 
785                 790                 795                 800


Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu 
                805                 810                 815


Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu 
            820                 825                 830


Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser 
        835                 840                 845


Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser 
    850                 855                 860


Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser 
865                 870                 875                 880


Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser 
                885                 890                 895


Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala 
            900                 905                 910


Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu 
        915                 920                 925


Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg 
    930                 935                 940


Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu 
945                 950                 955                 960


Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser 
                965                 970                 975


Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr 
            980                 985                 990


Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp 
        995                 1000                1005


Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile 
    1010                1015                1020


Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp 
1025                1030                1035                1040


Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly 
                1045                1050                1055


Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His 
            1060                1065                1070


Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr 
        1075                1080                1085


Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile 
    1090                1095                1100


Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro 
1105                1110                1115                1120


Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln 
                1125                1130                1135


Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu 
            1140                1145                1150


Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu 
        1155                1160                1165


Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile 
    1170                1175                1180


Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys 
1185                1190                1195                1200


Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn 
                1205                1210                1215


Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys 
            1220                1225                1230


Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile 
        1235                1240                1245


Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser 
    1250                1255                1260


Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile 
1265                1270                1275                1280


Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
                1285                1290


<210>  6688
<211>  570
<212>  DNA
<213>  Homo sapiens

<400>  6688
ttccggggct ctgcggtcct cggcctgtgc tggcagcctc ggagcccacc gagccgggcg     60

gctgggatga tgaaccggac gacccccgac caggagctgg tgccggcgtc ggagcccgtg    120

tgggagcggc cgtggtcggt ggaggagatc cgcaggagca gccagagctg gtcgctggcg    180

gccgacgcgg gcgtgagagg cgggccccgg ggacgcgaga gcggcagggg tgacgcttgg    240

cttgcgcgca ggagggccgg accgcgactg cccctgcacc tggcccgtcc cgttgcctgc    300

cctcttagga acacacgccc cgtttagccc ccgagaatgc caccctggca gtccccggcc    360

accagggaga ggggcagacc ctgaccgtgg cccagacgcg acgttccctt catggggttt    420

ctggctcagc tccatccgga ggggagatcc gtttccgcca cactgaggga ttgctcgggc    480

actagggagg cgattcctgt tgggacctgg actaaatggg gtgggaaaca agccagtatg    540

tggatatcct ttaatgggat tcttcaaatc                                     570


<210>  6689
<211>  86
<212>  PRT
<213>  Homo sapiens

<400>  6689

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Val Arg Gly Gly Pro Arg 
        35                  40                  45


Gly Arg Glu Ser Gly Arg Gly Asp Ala Trp Leu Ala Arg Arg Arg Ala 
    50                  55                  60


Gly Pro Arg Leu Pro Leu His Leu Ala Arg Pro Val Ala Cys Pro Leu 
65                  70                  75                  80


Arg Asn Thr Arg Pro Val 
                85


<210>  6690
<211>  2202
<212>  DNA
<213>  Homo sapiens

<400>  6690
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gaggaccagt ggaatattcc tgcttcacag acccacttag   1800

catctgacag caggtctaaa ggagaaccca gggattctgg gaccctccag agccaggagg   1860

ccaaggctgt gaaaaagacc agtctctttg aggaagacaa agaagatgat ctttttgcca   1920

ttgccaagga cagccaaaag aagacccaga gagtgtcact cctctttgaa gacgatgttg   1980

atagcggagg ctctctgttt ggctctcctc ccacatctgt tcctcctgca acaaaggaag   2040

gacttttgac tagatctgct caggaaacag tcaagcattc tgatttattt tcttcatcat   2100

ccccatggga caaaggaacc aagcctagaa ccaaaactgt tcttagcttg tttgatgagg   2160

aagaggataa aatggaagat caaaacatta tccaggctcc ac                      2202


<210>  6691
<211>  713
<212>  PRT
<213>  Homo sapiens

<400>  6691

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln His Thr Thr 
            180                 185                 190


Gln Met Ser Asp Glu Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala 
        195                 200                 205


Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr 
    210                 215                 220


Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala 
225                 230                 235                 240


Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr 
                245                 250                 255


Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys 
            260                 265                 270


Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro 
        275                 280                 285


Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly 
    290                 295                 300


Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser 
305                 310                 315                 320


Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val 
                325                 330                 335


Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly 
            340                 345                 350


Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser 
        355                 360                 365


Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg 
    370                 375                 380


Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp 
385                 390                 395                 400


Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser 
                405                 410                 415


Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu 
            420                 425                 430


Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val 
        435                 440                 445


Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu 
    450                 455                 460


Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys 
465                 470                 475                 480


Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln 
                485                 490                 495


Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro 
            500                 505                 510


Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe 
        515                 520                 525


Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg 
    530                 535                 540


Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala 
545                 550                 555                 560


Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser 
                565                 570                 575


Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp 
            580                 585                 590


Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser 
        595                 600                 605


Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp 
    610                 615                 620


Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val 
625                 630                 635                 640


Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro 
                645                 650                 655


Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys 
            660                 665                 670


His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys 
        675                 680                 685


Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys 
    690                 695                 700


Met Glu Asp Gln Asn Ile Ile Gln Ala 
705                 710


<210>  6692
<211>  4334
<212>  DNA
<213>  Homo sapiens

<400>  6692
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggatttgtt ttcttctcaa agtgcgagta acttaaaagg tgcatctctg ctgcctggca   1500

agctccccac gtcggtttcc ctgtttgatg atgaagatga agaggataat ctttttgggg   1560

gtacagctgc taagaagcag acattgtctc tacaagctca gagagaagag aaagcaaaag   1620

cctccgagct ctccaaaaag aaagcatctg ccctgttgtt cagcagtgat gaggaggacc   1680

agtggaatat tcctgcttca cagacccact tagcatctga cagcaggtct aaaggagaac   1740

ccagggattc tgggaccctc cagagccagg aggccaaggc tgtgaaaaag accagtctct   1800

ttgaggaaga caaagaagat gatctttttg ccattgccaa ggacagccaa aagaagaccc   1860

agagagtgtc actcctcttt gaagacgatg ttgatagcgg aggctctctg tttggctctc   1920

ctcccacatc tgttcctcct gcaacaaaga aaaaagagac tgtctctgag gcaccacctt   1980

tgctgttcag cgatgaagaa gagaaggagg cacaacttgg agtgaagtct gtggataaga   2040

aggttgagag tgccaaggag tcattaaaat ttgggagaac tgatgtggct gagtcagaaa   2100

aggaaggact tttgactaga tctgctcagg aaacagtcaa gcattctgat ttattttctt   2160

catcatcccc atgggacaaa ggaaccaagc ctagaaccaa aactgttctt agcttgtttg   2220

atgaggaaga ggataaaatg gaagatcaaa acattatcca ggctccacag aaagaagtag   2280

gaaagggctg cgatcctgat gcccacccca agagcacagg tgtcttccag gatgaagagc   2340

tgcttttcag ccacaagctc caaaaggaca atgacccaga tgttgacctt tttgctggca   2400

ccaaaaaaac caagctgtta gagccaagtg ttgggagcct gtttggggat gatgaagatg   2460

atgatctttt cagctctgcc aagtcccagc ctttggtaca agagaaaaag agagtagtga   2520

aaaaagacca ctctgttaac tctttcaaaa accagaaaca tcctgaatcc attcaaggta   2580

gtaaagaaaa aggcatatgg aagccggaaa cacctcaggc aaatttagcg atcaacccag   2640

cggccttgct gcccacagcg gcttcccaga tctctgaagt aaagcctgtt ttgccagaat   2700

tggcttttcc ttcatctgaa cacagaagga gccacggtct ggaaagtgtg cctgtccttc   2760

ccgggagtgg ggaggccggt gtgagttttg atcttccagc tcaggcagac accttacaca   2820

gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag accgcagacc cgtgcagcta   2880

ggcggctggc tgctcaggag tccagcgagg ctgaggacat gagcgtcccc agaggaccca   2940

ttgcacagtg ggctgatggc gccatttccc caaatggcca tcggccacag ctcagagcag   3000

ccagtggaga agacagcact gaggaggccc tggcagctgc cgctgcacct tgggaaggtg   3060

gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc tctgggtcat tccagagggg   3120

aggctgacct ttttgattct ggggacattt tttccacggg cactggatct cagtccgtgg   3180

agagaacaaa acccaaggca aagatagcag agaatcctgc caacccacca gtgggtggta   3240

aagcaaagag ccccatgttt cctgctctag gcgaggccag cagtgatgat gatctctttc   3300

agtctgctaa accaaaacca gcaaagaaaa caaatccctt tcctctcctg gaagatgagg   3360

atgacctctt tacagatcag aaagtcaaga agaatgagac aaaatccagt agtcagcagg   3420

atgtcatatt aacaacacaa gatatttttg aggatgatat atttgctacg gaagcaatta   3480

aaccctctca gaaaaccaga gagaaggaga aaacattgga atctaattta tttgatgata   3540

acattgatat ctttgctgac ttaactgtaa aaccaaaaga aaagtccaaa aagaaagtgg   3600

aagccaagtc tatatttgat gatgatatgg atgacatctt ctccactggt atccaggcta   3660

agacaaccaa accaaaaagc cgatctgcac aggccgcacc tgaaccaaga tttgaacaca   3720

aggtgtccaa catctttgat gatcccctga atgcctttgg aggccagtag agcacacagg   3780

gtatccacat gttaccctgc agctacattg ttgagttagt gatgatattg tatatgctca   3840

tggtcttaac tggattacaa aaagcaaata ctagaacagc tagctcatct tttacccaat   3900

gtacttagta tttttctgca ctggtttaat catgcttaat actacaaaac aaaaataaat   3960

atttcacagt ggttggtttg ttttgttttt aaaccacagt ttgatttagt tagccttgct   4020

ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc tctttgtggc tttcatgggc   4080

agggaatctc agagatagca aatgccacct gaccagaagt ctttgttata tggatgggaa   4140

ccctaactta gggcttgggc aggggaaaga gaaagaagat gagagattat acttcatgag   4200

tcttagcaat atgggagcag gttttcactg aattctgagg gtgcctctgc atgtcctcca   4260

aggcaaagtt tggcaaactg tggccccccc actgtcatat tttgttaata aaattttatt   4320

ggaacacaat caca                                                     4334


<210>  6693
<211>  1236
<212>  PRT
<213>  Homo sapiens

<400>  6693

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln His Thr Thr 
            180                 185                 190


Gln Met Ser Asp Glu Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala 
        195                 200                 205


Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr 
    210                 215                 220


Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala 
225                 230                 235                 240


Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr 
                245                 250                 255


Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys 
            260                 265                 270


Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro 
        275                 280                 285


Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly 
    290                 295                 300


Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser 
305                 310                 315                 320


Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val 
                325                 330                 335


Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly 
            340                 345                 350


Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser 
        355                 360                 365


Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg 
    370                 375                 380


Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp 
385                 390                 395                 400


Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser 
                405                 410                 415


Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu 
            420                 425                 430


Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val 
        435                 440                 445


Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu Phe 
    450                 455                 460


Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly 
465                 470                 475                 480


Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp 
                485                 490                 495


Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln 
            500                 505                 510


Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys 
        515                 520                 525


Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile 
    530                 535                 540


Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu 
545                 550                 555                 560


Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys 
                565                 570                 575


Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile 
            580                 585                 590


Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu 
        595                 600                 605


Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser 
    610                 615                 620


Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro 
625                 630                 635                 640


Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys 
                645                 650                 655


Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly 
            660                 665                 670


Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser 
        675                 680                 685


Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro 
    690                 695                 700


Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe 
705                 710                 715                 720


Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro 
                725                 730                 735


Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser 
            740                 745                 750


Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln 
        755                 760                 765


Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr 
    770                 775                 780


Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp 
785                 790                 795                 800


Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys 
                805                 810                 815


Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln 
            820                 825                 830


Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys 
        835                 840                 845


Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
    850                 855                 860


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
865                 870                 875                 880


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
                885                 890                 895


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
            900                 905                 910


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
        915                 920                 925


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
    930                 935                 940


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
945                 950                 955                 960


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
                965                 970                 975


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
            980                 985                 990


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
        995                 1000                1005


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
    1010                1015                1020


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
1025                1030                1035                1040


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
                1045                1050                1055


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
            1060                1065                1070


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
        1075                1080                1085


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
    1090                1095                1100


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
1105                1110                1115                1120


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
                1125                1130                1135


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
            1140                1145                1150


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
        1155                1160                1165


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
    1170                1175                1180


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
1185                1190                1195                1200


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
                1205                1210                1215


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
            1220                1225                1230


Phe Gly Gly Gln 
        1235


<210>  6694
<211>  4536
<212>  DNA
<213>  Homo sapiens

<400>  6694
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gaggaccagt ggaatattcc tgcttcacag acccacttag   1800

catctgacag caggtctaaa ggagaaccca gggattctgg gaccctccag agccaggagg   1860

ccaaggctgt gaaaaagacc agtctctttg aggaagacaa agaagatgat ctttttgcca   1920

ttgccaagga cagatacatc ctacctccta ttgttcccga agttgtctgt caagttttgt   1980

gtatggaaag taattcatac cttcatcaga tctcaaaaga agctttacac acacaagaag   2040

aagttgagcc aaaagaagac ccagagagtg tcactcctct ttgaagacga tgttgatagc   2100

ggaggctctc tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag   2160

actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga ggcacaactt   2220

ggagtgaagt ctgtggataa gaaggttgag agtgccaagg agtcattaaa atttgggaga   2280

actgatgtgg ctgagtcaga aaaggaagga cttttgacta gatctgctca ggaaacagtc   2340

aagcattctg atttattttc ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc   2400

aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc   2460

caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc caagagcaca   2520

ggtgtcttcc aggatgaaga gctgcttttc agccacaagc tccaaaagga caatgaccca   2580

gatgttgacc tttttgctgg caccaaaaaa accaagctgt tagagccaag tgttgggagc   2640

ctgtttgggg atgatgaaga tgatgatctt ttcagctctg ccaagtccca gcctttggta   2700

caagagaaaa agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa   2760

catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga aacacctcag   2820

gcaaatttag cgatcaaccc agcggccttg ctgcccacag cggcttccca gatctctgaa   2880

gtaaagcctg ttttgccaga attggctttt ccttcatctg aacacagaag gagccacggt   2940

ctggaaagtg tgcctgtcct tcccgggagt ggggaggccg gtgtgagttt tgatcttcca   3000

gctcaggcag acaccttaca cagtgcaaac aagagccgtg tcaagatgag agggaagcgt   3060

agaccgcaga cccgtgcagc taggcggctg gctgctcagg agtccagcga ggctgaggac   3120

atgagcgtcc ccagaggacc cattgcacag tgggctgatg gcgccatttc cccaaatggc   3180

catcggccac agctcagagc agccagtgga gaagacagca ctgaggaggc cctggcagct   3240

gccgctgcac cttgggaagg tggtcctgtg cctggagtgg acacaagccc ctttgcaaag   3300

tctctgggtc attccagagg ggaggctgac ctttttgatt ctggggacat tttttccacg   3360

ggcactggat ctcagtccgt ggagagaaca aaacccaagg caaagatagc agagaatcct   3420

gccaacccac cagtgggtgg taaagcaaag agccccatgt ttcctgctct aggcgaggcc   3480

agcagtgatg atgatctctt tcagtctgct aaaccaaaac cagcaaagaa aacaaatccc   3540

tttcctctcc tggaagatga ggatgacctc tttacagatc agaaagtcaa gaagaatgag   3600

acaaaatcca gtagtcagca ggatgtcata ttaacaacac aagatatttt tgaggatgat   3660

atatttgcta cggaagcaat taaaccctct cagaaaacca gagagaagga gaaaacattg   3720

gaatctaatt tatttgatga taacattgat atctttgctg acttaactgt aaaaccaaaa   3780

gaaaagtcca aaaagaaagt ggaagccaag tctatatttg atgatgatat ggatgacatc   3840

ttctccactg gtatccaggc taagacaacc aaaccaaaaa gccgatctgc acaggccgca   3900

cctgaaccaa gatttgaaca caaggtgtcc aacatctttg atgatcccct gaatgccttt   3960

ggaggccagt agagcacaca gggtatccac atgttaccct gcagctacat tgttgagtta   4020

gtgatgatat tgtatatgct catggtctta actggattac aaaaagcaaa tactagaaca   4080

gctagctcat cttttaccca atgtacttag tatttttctg cactggttta atcatgctta   4140

atactacaaa acaaaaataa atatttcaca gtggttggtt tgttttgttt ttaaaccaca   4200

gtttgattta gttagccttg ctggggccat aatatgcttc agggtgtgta aaagaagaaa   4260

tctctttgtg gctttcatgg gcagggaatc tcagagatag caaatgccac ctgaccagaa   4320

gtctttgtta tatggatggg aaccctaact tagggcttgg gcaggggaaa gagaaagaag   4380

atgagagatt atacttcatg agtcttagca atatgggagc aggttttcac tgaattctga   4440

gggtgcctct gcatgtcctc caaggcaaag tttggcaaac tgtggccccc ccactgtcat   4500

attttgttaa taaaatttta ttggaacaca atcaca                             4536


<210>  6695
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6695

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6696
<211>  4161
<212>  DNA
<213>  Homo sapiens

<400>  6696
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gagccaaaag aagacccaga gagtgtcact cctctttgaa   1800

gacgatgttg atagcggagg ctctctgttt ggctctcctc ccacatctgt tcctcctgca   1860

acaaaggaag gacttttgac tagatctgct caggaaacag tcaagcattc tgatttattt   1920

tcttcatcat ccccatggga caaaggaacc aagcctagaa ccaaaactgt tcttagcttg   1980

tttgatgagg aagaggataa aatggaagat caaaacatta tccaggctcc acagaaagaa   2040

gtaggaaagg gctgcgatcc tgatgcccac cccaagagca caggtgtctt ccaggatgaa   2100

gagctgcttt tcagccacaa gctccaaaag gacaatgacc cagatgttga cctttttgct   2160

ggcaccaaaa aaaccaagct gttagagcca agtgttggga gcctgtttgg ggatgatgaa   2220

gatgatgatc ttttcagctc tgccaagtcc cagcctttgg tacaagagaa aaagagagta   2280

gtgaaaaaag accactctgt taactctttc aaaaaccaga aacatcctga atccattcaa   2340

ggtagtaaag aaaaaggcat atggaagccg gaaacacctc aggactcatc aggtctcgct   2400

ccatttaaaa ccaaagaacc atccactcgg atcgggaaga tacaagcaaa tttagcgatc   2460

aacccagcgg ccttgctgcc cacagcggct tcccagatct ctgaagtaaa gcctgttttg   2520

ccagaattgg cttttccttc atctgaacac agaaggagcc acggtctgga aagtgtgcct   2580

gtccttcccg ggagtgggga ggccggtgtg agttttgatc ttccagctca ggcagacacc   2640

ttacacagtg caaacaagag ccgtgtcaag atgagaggga agcgtagacc gcagacccgt   2700

gcagctaggc ggctggctgc tcaggagtcc agcgaggctg aggacatgag cgtccccaga   2760

ggacccattg cacagtgggc tgatggcgcc atttccccaa atggccatcg gccacagctc   2820

agagcagcca gtggagaaga cagcactgag gaggccctgg cagctgccgc tgcaccttgg   2880

gaaggtggtc ctgtgcctgg agtggacaca agcccctttg caaagtctct gggtcattcc   2940

agaggggagg ctgacctttt tgattctggg gacatttttt ccacgggcac tggatctcag   3000

tccgtggaga gaacaaaacc caaggcaaag atagcagaga atcctgccaa cccaccagtg   3060

ggtggtaaag caaagagccc catgtttcct gctctaggcg aggccagcag tgatgatgat   3120

ctctttcagt ctgctaaacc aaaaccagca aagaaaacaa atccctttcc tctcctggaa   3180

gatgaggatg acctctttac agatcagaaa gtcaagaaga atgagacaaa atccagtagt   3240

cagcaggatg tcatattaac aacacaagat atttttgagg atgatatatt tgctacggaa   3300

gcaattaaac cctctcagaa aaccagagag aaggagaaaa cattggaatc taatttattt   3360

gatgataaca ttgatatctt tgctgactta actgtaaaac caaaagaaaa gtccaaaaag   3420

aaagtggaag ccaagtctat atttgatgat gatatggatg acatcttctc cactggtatc   3480

caggctaaga caaccaaacc aaaaagccga tctgcacagg ccgcacctga accaagattt   3540

gaacacaagg tgtccaacat ctttgatgat cccctgaatg cctttggagg ccagtagagc   3600

acacagggta tccacatgtt accctgcagc tacattgttg agttagtgat gatattgtat   3660

atgctcatgg tcttaactgg attacaaaaa gcaaatacta gaacagctag ctcatctttt   3720

acccaatgta cttagtattt ttctgcactg gtttaatcat gcttaatact acaaaacaaa   3780

aataaatatt tcacagtggt tggtttgttt tgtttttaaa ccacagtttg atttagttag   3840

ccttgctggg gccataatat gcttcagggt gtgtaaaaga agaaatctct ttgtggcttt   3900

catgggcagg gaatctcaga gatagcaaat gccacctgac cagaagtctt tgttatatgg   3960

atgggaaccc taacttaggg cttgggcagg ggaaagagaa agaagatgag agattatact   4020

tcatgagtct tagcaatatg ggagcaggtt ttcactgaat tctgagggtg cctctgcatg   4080

tcctccaagg caaagtttgg caaactgtgg cccccccact gtcatatttt gttaataaaa   4140

ttttattgga acacaatcac a                                             4161


<210>  6697
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6697

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6698
<211>  4397
<212>  DNA
<213>  Homo sapiens

<400>  6698
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggatttgtt ttcttctcaa agtgcgagta acttaaaagg tgcatctctg ctgcctggca   1500

agctccccac gtcggtttcc ctgtttgatg atgaagatga agaggataat ctttttgggg   1560

gtacagctgc taagaagcag acattgtctc tacaagctca gagagaagag aaagcaaaag   1620

cctccgagct ctccaaaaag aaagcatctg ccctgttgtt cagcagtgat gaggaggacc   1680

agtggaatat tcctgcttca cagacccact tagcatctga cagcaggtct aaaggagaac   1740

ccagggattc tgggaccctc cagagccagg aggccaaggc tgtgaaaaag accagtctct   1800

ttgaggaaga caaagaagat gatctttttg ccattgccaa ggacagccaa aagaagaccc   1860

agagagtgtc actcctcttt gaagacgatg ttgatagcgg aggctctctg tttggctctc   1920

ctcccacatc tgttcctcct gcaacaaaga aaaaagagac tgtctctgag gcaccacctt   1980

tgctgttcag cgatgaagaa gagaaggagg cacaacttgg agtgaagtct gtggataaga   2040

aggttgagag tgccaaggag tcattaaaat ttgggagaac tgatgtggct gagtcagaaa   2100

aggaaggact tttgactaga tctgctcagg aaacagtcaa gcattctgat ttattttctt   2160

catcatcccc atgggacaaa ggaaccaagc ctagaaccaa aactgttctt agcttgtttg   2220

atgaggaaga ggataaaatg gaagatcaaa acattatcca ggctccacag aaagaagtag   2280

gaaagggctg cgatcctgat gcccacccca agagcacagg tgtcttccag gatgaagagc   2340

tgcttttcag ccacaagctc caaaaggaca atgacccaga tgttgacctt tttgctggca   2400

ccaaaaaaac caagctgtta gagccaagtg ttgggagcct gtttggggat gatgaagatg   2460

atgatctttt cagctctgcc aagtcccagc ctttggtaca agagaaaaag agagtagtga   2520

aaaaagacca ctctgttaac tctttcaaaa accagaaaca tcctgaatcc attcaaggta   2580

gtaaagaaaa aggcatatgg aagccggaaa cacctcagga ctcatcaggt ctcgctccat   2640

ttaaaaccaa agaaccatcc actcggatcg ggaagataca agcaaattta gcgatcaacc   2700

cagcggcctt gctgcccaca gcggcttccc agatctctga agtaaagcct gttttgccag   2760

aattggcttt tccttcatct gaacacagaa ggagccacgg tctggaaagt gtgcctgtcc   2820

ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc agctcaggca gacaccttac   2880

acagtgcaaa caagagccgt gtcaagatga gagggaagcg tagaccgcag acccgtgcag   2940

ctaggcggct ggctgctcag gagtccagcg aggctgagga catgagcgtc cccagaggac   3000

ccattgcaca gtgggctgat ggcgccattt ccccaaatgg ccatcggcca cagctcagag   3060

cagccagtgg agaagacagc actgaggagg ccctggcagc tgccgctgca ccttgggaag   3120

gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa gtctctgggt cattccagag   3180

gggaggctga cctttttgat tctggggaca ttttttccac gggcactgga tctcagtccg   3240

tggagagaac aaaacccaag gcaaagatag cagagaatcc tgccaaccca ccagtgggtg   3300

gtaaagcaaa gagccccatg tttcctgctc taggcgaggc cagcagtgat gatgatctct   3360

ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc ctttcctctc ctggaagatg   3420

aggatgacct ctttacagat cagaaagtca agaagaatga gacaaaatcc agtagtcagc   3480

aggatgtcat attaacaaca caagatattt ttgaggatga tatatttgct acggaagcaa   3540

ttaaaccctc tcagaaaacc agagagaagg agaaaacatt ggaatctaat ttatttgatg   3600

ataacattga tatctttgct gacttaactg taaaaccaaa agaaaagtcc aaaaagaaag   3660

tggaagccaa gtctatattt gatgatgata tggatgacat cttctccact ggtatccagg   3720

ctaagacaac caaaccaaaa agccgatctg cacaggccgc acctgaacca agatttgaac   3780

acaaggtgtc caacatcttt gatgatcccc tgaatgcctt tggaggccag tagagcacac   3840

agggtatcca catgttaccc tgcagctaca ttgttgagtt agtgatgata ttgtatatgc   3900

tcatggtctt aactggatta caaaaagcaa atactagaac agctagctca tcttttaccc   3960

aatgtactta gtatttttct gcactggttt aatcatgctt aatactacaa aacaaaaata   4020

aatatttcac agtggttggt ttgttttgtt tttaaaccac agtttgattt agttagcctt   4080

gctggggcca taatatgctt cagggtgtgt aaaagaagaa atctctttgt ggctttcatg   4140

ggcagggaat ctcagagata gcaaatgcca cctgaccaga agtctttgtt atatggatgg   4200

gaaccctaac ttagggcttg ggcaggggaa agagaaagaa gatgagagat tatacttcat   4260

gagtcttagc aatatgggag caggttttca ctgaattctg agggtgcctc tgcatgtcct   4320

ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca tattttgtta ataaaatttt   4380

attggaacac aatcaca                                                  4397


<210>  6699
<211>  1257
<212>  PRT
<213>  Homo sapiens

<400>  6699

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln His Thr Thr 
            180                 185                 190


Gln Met Ser Asp Glu Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala 
        195                 200                 205


Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr 
    210                 215                 220


Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala 
225                 230                 235                 240


Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr 
                245                 250                 255


Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys 
            260                 265                 270


Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro 
        275                 280                 285


Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly 
    290                 295                 300


Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser 
305                 310                 315                 320


Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val 
                325                 330                 335


Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly 
            340                 345                 350


Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser 
        355                 360                 365


Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg 
    370                 375                 380


Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp 
385                 390                 395                 400


Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser 
                405                 410                 415


Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu 
            420                 425                 430


Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val 
        435                 440                 445


Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu Phe 
    450                 455                 460


Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly 
465                 470                 475                 480


Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp 
                485                 490                 495


Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln 
            500                 505                 510


Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys 
        515                 520                 525


Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile 
    530                 535                 540


Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu 
545                 550                 555                 560


Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys 
                565                 570                 575


Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile 
            580                 585                 590


Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu 
        595                 600                 605


Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser 
    610                 615                 620


Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro 
625                 630                 635                 640


Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys 
                645                 650                 655


Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly 
            660                 665                 670


Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser 
        675                 680                 685


Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro 
    690                 695                 700


Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe 
705                 710                 715                 720


Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro 
                725                 730                 735


Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser 
            740                 745                 750


Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln 
        755                 760                 765


Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr 
    770                 775                 780


Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp 
785                 790                 795                 800


Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys 
                805                 810                 815


Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln 
            820                 825                 830


Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys 
        835                 840                 845


Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys 
    850                 855                 860


Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn 
865                 870                 875                 880


Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys 
                885                 890                 895


Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser 
            900                 905                 910


His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly 
        915                 920                 925


Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn 
    930                 935                 940


Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala 
945                 950                 955                 960


Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser 
                965                 970                 975


Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro 
            980                 985                 990


Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr 
        995                 1000                1005


Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val 
    1010                1015                1020


Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg 
1025                1030                1035                1040


Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr 
                1045                1050                1055


Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu 
            1060                1065                1070


Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe 
        1075                1080                1085


Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala 
    1090                1095                1100


Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp 
1105                1110                1115                1120


Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys 
                1125                1130                1135


Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu 
            1140                1145                1150


Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg 
        1155                1160                1165


Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp 
    1170                1175                1180


Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys 
1185                1190                1195                1200


Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser 
                1205                1210                1215


Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln 
            1220                1225                1230


Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp 
        1235                1240                1245


Asp Pro Leu Asn Ala Phe Gly Gly Gln 
    1250                1255


<210>  6700
<211>  4373
<212>  DNA
<213>  Homo sapiens

<400>  6700
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg aggaccagtg gaatattcct gcttcacaga   1680

cccacttagc atctgacagc aggtctaaag gagaacccag ggattctggg accctccaga   1740

gccaggaggc caaggctgtg aaaaagacca gtctctttga ggaagacaaa gaagatgatc   1800

tttttgccat tgccaaggac agccaaaaga agacccagag agtgtcactc ctctttgaag   1860

acgatgttga tagcggaggc tctctgtttg gctctcctcc cacatctgtt cctcctgcaa   1920

caaagaaaaa agagactgtc tctgaggcac cacctttgct gttcagcgat gaagaagaga   1980

aggaggcaca acttggagtg aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat   2040

taaaatttgg gagaactgat gtggctgagt cagaaaagga aggacttttg actagatctg   2100

ctcaggaaac agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa   2160

ccaagcctag aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag   2220

atcaaaacat tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc   2280

accccaagag cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa   2340

aggacaatga cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc   2400

caagtgttgg gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt   2460

cccagccttt ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt   2520

tcaaaaacca gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc   2580

cggaaacacc tcaggactca tcaggtctcg ctccatttaa aaccaaagaa ccatccactc   2640

ggatcgggaa gatacaagca aatttagcga tcaacccagc ggccttgctg cccacagcgg   2700

cttcccagat ctctgaagta aagcctgttt tgccagaatt ggcttttcct tcatctgaac   2760

acagaaggag ccacggtctg gaaagtgtgc ctgtccttcc cgggagtggg gaggccggtg   2820

tgagttttga tcttccagct caggcagaca ccttacacag tgcaaacaag agccgtgtca   2880

agatgagagg gaagcgtaga ccgcagaccc gtgcagctag gcggctggct gctcaggagt   2940

ccagcgaggc tgaggacatg agcgtcccca gaggacccat tgcacagtgg gctgatggcg   3000

ccatttcccc aaatggccat cggccacagc tcagagcagc cagtggagaa gacagcactg   3060

aggaggccct ggcagctgcc gctgcacctt gggaaggtgg tcctgtgcct ggagtggaca   3120

caagcccctt tgcaaagtct ctgggtcatt ccagagggga ggctgacctt tttgattctg   3180

gggacatttt ttccacgggc actggatctc agtccgtgga gagaacaaaa cccaaggcaa   3240

agatagcaga gaatcctgcc aacccaccag tgggtggtaa agcaaagagc cccatgtttc   3300

ctgctctagg cgaggccagc agtgatgatg atctctttca gtctgctaaa ccaaaaccag   3360

caaagaaaac aaatcccttt cctctcctgg aagatgagga tgacctcttt acagatcaga   3420

aagtcaagaa gaatgagaca aaatccagta gtcagcagga tgtcatatta acaacacaag   3480

atatttttga ggatgatata tttgctacgg aagcaattaa accctctcag aaaaccagag   3540

agaaggagaa aacattggaa tctaatttat ttgatgataa cattgatatc tttgctgact   3600

taactgtaaa accaaaagaa aagtccaaaa agaaagtgga agccaagtct atatttgatg   3660

atgatatgga tgacatcttc tccactggta tccaggctaa gacaaccaaa ccaaaaagcc   3720

gatctgcaca ggccgcacct gaaccaagat ttgaacacaa ggtgtccaac atctttgatg   3780

atcccctgaa tgcctttgga ggccagtaga gcacacaggg tatccacatg ttaccctgca   3840

gctacattgt tgagttagtg atgatattgt atatgctcat ggtcttaact ggattacaaa   3900

aagcaaatac tagaacagct agctcatctt ttacccaatg tacttagtat ttttctgcac   3960

tggtttaatc atgcttaata ctacaaaaca aaaataaata tttcacagtg gttggtttgt   4020

tttgttttta aaccacagtt tgatttagtt agccttgctg gggccataat atgcttcagg   4080

gtgtgtaaaa gaagaaatct ctttgtggct ttcatgggca gggaatctca gagatagcaa   4140

atgccacctg accagaagtc tttgttatat ggatgggaac cctaacttag ggcttgggca   4200

ggggaaagag aaagaagatg agagattata cttcatgagt cttagcaata tgggagcagg   4260

ttttcactga attctgaggg tgcctctgca tgtcctccaa ggcaaagttt ggcaaactgt   4320

ggccccccca ctgtcatatt ttgttaataa aattttattg gaacacaatc aca          4373


<210>  6701
<211>  1249
<212>  PRT
<213>  Homo sapiens

<400>  6701

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln Lys Arg Ser 
            180                 185                 190


Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp 
        195                 200                 205


Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu 
    210                 215                 220


Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro 
225                 230                 235                 240


Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp 
                245                 250                 255


Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly 
            260                 265                 270


Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu 
        275                 280                 285


Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser 
    290                 295                 300


Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe 
305                 310                 315                 320


Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys 
                325                 330                 335


Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly 
            340                 345                 350


Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp 
        355                 360                 365


Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val 
    370                 375                 380


Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys 
385                 390                 395                 400


Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu 
                405                 410                 415


Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn 
            420                 425                 430


Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp 
        435                 440                 445


Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu 
    450                 455                 460


Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu 
465                 470                 475                 480


Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala 
                485                 490                 495


Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys 
            500                 505                 510


Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser 
        515                 520                 525


Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala 
    530                 535                 540


Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln 
545                 550                 555                 560


Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp 
                565                 570                 575


Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr 
            580                 585                 590


Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser 
        595                 600                 605


Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys 
    610                 615                 620


Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu 
625                 630                 635                 640


Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser 
                645                 650                 655


Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu 
            660                 665                 670


Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser 
        675                 680                 685


Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg 
    690                 695                 700


Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu 
705                 710                 715                 720


Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys 
                725                 730                 735


Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu 
            740                 745                 750


Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp 
        755                 760                 765


Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly 
    770                 775                 780


Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys 
785                 790                 795                 800


Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His 
                805                 810                 815


Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly 
            820                 825                 830


Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser 
        835                 840                 845


Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys 
    850                 855                 860


Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala 
865                 870                 875                 880


Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe 
                885                 890                 895


Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val 
            900                 905                 910


Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln 
        915                 920                 925


Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly 
    930                 935                 940


Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu 
945                 950                 955                 960


Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln 
                965                 970                 975


Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg 
            980                 985                 990


Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala 
        995                 1000                1005


Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe 
    1010                1015                1020


Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser 
1025                1030                1035                1040


Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr 
                1045                1050                1055


Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly 
            1060                1065                1070


Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser 
        1075                1080                1085


Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr 
    1090                1095                1100


Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln 
1105                1110                1115                1120


Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile 
                1125                1130                1135


Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala 
            1140                1145                1150


Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser 
        1155                1160                1165


Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys 
    1170                1175                1180


Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp 
1185                1190                1195                1200


Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr 
                1205                1210                1215


Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu 
            1220                1225                1230


His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly 
        1235                1240                1245


Gln 



<210>  6702
<211>  4050
<212>  DNA
<213>  Homo sapiens

<400>  6702
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg agccaaaaga agacccagag agtgtcactc   1680

ctctttgaag acgatgttga tagcggaggc tctctgtttg gctctcctcc cacatctgtt   1740

cctcctgcaa caaaggaagg acttttgact agatctgctc aggaaacagt caagcattct   1800

gatttatttt cttcatcatc cccatgggac aaaggaacca agcctagaac caaaactgtt   1860

cttagcttgt ttgatgagga agaggataaa atggaagatc aaaacattat ccaggctcca   1920

cagaaagaag taggaaaggg ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc   1980

caggatgaag agctgctttt cagccacaag ctccaaaagg acaatgaccc agatgttgac   2040

ctttttgctg gcaccaaaaa aaccaagctg ttagagccaa gtgttgggag cctgtttggg   2100

gatgatgaag atgatgatct tttcagctct gccaagtccc agcctttggt acaagagaaa   2160

aagagagtag tgaaaaaaga ccactctgtt aactctttca aaaaccagaa acatcctgaa   2220

tccattcaag gtagtaaaga aaaaggcata tggaagccgg aaacacctca ggactcatca   2280

ggtctcgctc catttaaaac caaagaacca tccactcgga tcgggaagat acaagcaaat   2340

ttagcgatca acccagcggc cttgctgccc acagcggctt cccagatctc tgaagtaaag   2400

cctgttttgc cagaattggc ttttccttca tctgaacaca gaaggagcca cggtctggaa   2460

agtgtgcctg tccttcccgg gagtggggag gccggtgtga gttttgatct tccagctcag   2520

gcagacacct tacacagtgc aaacaagagc cgtgtcaaga tgagagggaa gcgtagaccg   2580

cagacccgtg cagctaggcg gctggctgct caggagtcca gcgaggctga ggacatgagc   2640

gtccccagag gacccattgc acagtgggct gatggcgcca tttccccaaa tggccatcgg   2700

ccacagctca gagcagccag tggagaagac agcactgagg aggccctggc agctgccgct   2760

gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa gcccctttgc aaagtctctg   2820

ggtcattcca gaggggaggc tgaccttttt gattctgggg acattttttc cacgggcact   2880

ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga tagcagagaa tcctgccaac   2940

ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg ctctaggcga ggccagcagt   3000

gatgatgatc tctttcagtc tgctaaacca aaaccagcaa agaaaacaaa tccctttcct   3060

ctcctggaag atgaggatga cctctttaca gatcagaaag tcaagaagaa tgagacaaaa   3120

tccagtagtc agcaggatgt catattaaca acacaagata tttttgagga tgatatattt   3180

gctacggaag caattaaacc ctctcagaaa accagagaga aggagaaaac attggaatct   3240

aatttatttg atgataacat tgatatcttt gctgacttaa ctgtaaaacc aaaagaaaag   3300

tccaaaaaga aagtggaagc caagtctata tttgatgatg atatggatga catcttctcc   3360

actggtatcc aggctaagac aaccaaacca aaaagccgat ctgcacaggc cgcacctgaa   3420

ccaagatttg aacacaaggt gtccaacatc tttgatgatc ccctgaatgc ctttggaggc   3480

cagtagagca cacagggtat ccacatgtta ccctgcagct acattgttga gttagtgatg   3540

atattgtata tgctcatggt cttaactgga ttacaaaaag caaatactag aacagctagc   3600

tcatctttta cccaatgtac ttagtatttt tctgcactgg tttaatcatg cttaatacta   3660

caaaacaaaa ataaatattt cacagtggtt ggtttgtttt gtttttaaac cacagtttga   3720

tttagttagc cttgctgggg ccataatatg cttcagggtg tgtaaaagaa gaaatctctt   3780

tgtggctttc atgggcaggg aatctcagag atagcaaatg ccacctgacc agaagtcttt   3840

gttatatgga tgggaaccct aacttagggc ttgggcaggg gaaagagaaa gaagatgaga   3900

gattatactt catgagtctt agcaatatgg gagcaggttt tcactgaatt ctgagggtgc   3960

ctctgcatgt cctccaaggc aaagtttggc aaactgtggc ccccccactg tcatattttg   4020

ttaataaaat tttattggaa cacaatcaca                                    4050


<210>  6703
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6703

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6704
<211>  4421
<212>  DNA
<213>  Homo sapiens

<400>  6704
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gaggaccagt ggaatattcc tgcttcacag acccacttag   1800

catctgacag caggtctaaa ggagaaccca gggattctgg gaccctccag agccaggagg   1860

ccaaggctgt gaaaaagacc agtctctttg aggaagacaa agaagatgat ctttttgcca   1920

ttgccaagga cagccaaaag aagacccaga gagtgtcact cctctttgaa gacgatgttg   1980

atagcggagg ctctctgttt ggctctcctc ccacatctgt tcctcctgca acaaagaaaa   2040

aagagactgt ctctgaggca ccacctttgc tgttcagcga tgaagaagag aaggaggcac   2100

aacttggagt gaagtctgtg gataagaagg ttgagagtgc caaggagtca ttaaaatttg   2160

ggagaactga tgtggctgag tcagaaaagg aaggactttt gactagatct gctcaggaaa   2220

cagtcaagca ttctgattta ttttcttcat catccccatg ggacaaagga accaagccta   2280

gaaccaaaac tgttcttagc ttgtttgatg aggaagagga taaaatggaa gatcaaaaca   2340

ttatccaggc tccacagaaa gaagtaggaa agggctgcga tcctgatgcc caccccaaga   2400

gcacaggtgt cttccaggat gaagagctgc ttttcagcca caagctccaa aaggacaatg   2460

acccagatgt tgaccttttt gctggcacca aaaaaaccaa gctgttagag ccaagtgttg   2520

ggagcctgtt tggggatgat gaagatgatg atcttttcag ctctgccaag tcccagcctt   2580

tggtacaaga gaaaaagaga gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc   2640

agaaacatcc tgaatccatt caaggtagta aagaaaaagg catatggaag ccggaaacac   2700

ctcaggcaaa tttagcgatc aacccagcgg ccttgctgcc cacagcggct tcccagatct   2760

ctgaagtaaa gcctgttttg ccagaattgg cttttccttc atctgaacac agaaggagcc   2820

acggtctgga aagtgtgcct gtccttcccg ggagtgggga ggccggtgtg agttttgatc   2880

ttccagctca ggcagacacc ttacacagtg caaacaagag ccgtgtcaag atgagaggga   2940

agcgtagacc gcagacccgt gcagctaggc ggctggctgc tcaggagtcc agcgaggctg   3000

aggacatgag cgtccccaga ggacccattg cacagtgggc tgatggcgcc atttccccaa   3060

atggccatcg gccacagctc agagcagcca gtggagaaga cagcactgag gaggccctgg   3120

cagctgccgc tgcaccttgg gaaggtggtc ctgtgcctgg agtggacaca agcccctttg   3180

caaagtctct gggtcattcc agaggggagg ctgacctttt tgattctggg gacatttttt   3240

ccacgggcac tggatctcag tccgtggaga gaacaaaacc caaggcaaag atagcagaga   3300

atcctgccaa cccaccagtg ggtggtaaag caaagagccc catgtttcct gctctaggcg   3360

aggccagcag tgatgatgat ctctttcagt ctgctaaacc aaaaccagca aagaaaacaa   3420

atccctttcc tctcctggaa gatgaggatg acctctttac agatcagaaa gtcaagaaga   3480

atgagacaaa atccagtagt cagcaggatg tcatattaac aacacaagat atttttgagg   3540

atgatatatt tgctacggaa gcaattaaac cctctcagaa aaccagagag aaggagaaaa   3600

cattggaatc taatttattt gatgataaca ttgatatctt tgctgactta actgtaaaac   3660

caaaagaaaa gtccaaaaag aaagtggaag ccaagtctat atttgatgat gatatggatg   3720

acatcttctc cactggtatc caggctaaga caaccaaacc aaaaagccga tctgcacagg   3780

ccgcacctga accaagattt gaacacaagg tgtccaacat ctttgatgat cccctgaatg   3840

cctttggagg ccagtagagc acacagggta tccacatgtt accctgcagc tacattgttg   3900

agttagtgat gatattgtat atgctcatgg tcttaactgg attacaaaaa gcaaatacta   3960

gaacagctag ctcatctttt acccaatgta cttagtattt ttctgcactg gtttaatcat   4020

gcttaatact acaaaacaaa aataaatatt tcacagtggt tggtttgttt tgtttttaaa   4080

ccacagtttg atttagttag ccttgctggg gccataatat gcttcagggt gtgtaaaaga   4140

agaaatctct ttgtggcttt catgggcagg gaatctcaga gatagcaaat gccacctgac   4200

cagaagtctt tgttatatgg atgggaaccc taacttaggg cttgggcagg ggaaagagaa   4260

agaagatgag agattatact tcatgagtct tagcaatatg ggagcaggtt ttcactgaat   4320

tctgagggtg cctctgcatg tcctccaagg caaagtttgg caaactgtgg cccccccact   4380

gtcatatttt gttaataaaa ttttattgga acacaatcac a                       4421


<210>  6705
<211>  1265
<212>  PRT
<213>  Homo sapiens

<400>  6705

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln His Thr Thr 
            180                 185                 190


Gln Met Ser Asp Glu Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala 
        195                 200                 205


Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr 
    210                 215                 220


Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala 
225                 230                 235                 240


Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr 
                245                 250                 255


Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys 
            260                 265                 270


Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro 
        275                 280                 285


Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly 
    290                 295                 300


Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser 
305                 310                 315                 320


Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val 
                325                 330                 335


Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly 
            340                 345                 350


Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser 
        355                 360                 365


Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg 
    370                 375                 380


Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp 
385                 390                 395                 400


Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser 
                405                 410                 415


Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu 
            420                 425                 430


Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val 
        435                 440                 445


Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu 
    450                 455                 460


Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys 
465                 470                 475                 480


Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln 
                485                 490                 495


Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro 
            500                 505                 510


Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe 
        515                 520                 525


Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg 
    530                 535                 540


Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala 
545                 550                 555                 560


Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser 
                565                 570                 575


Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp 
            580                 585                 590


Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser 
        595                 600                 605


Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp 
    610                 615                 620


Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val 
625                 630                 635                 640


Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro 
                645                 650                 655


Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe 
            660                 665                 670


Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp 
        675                 680                 685


Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp 
    690                 695                 700


Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu 
705                 710                 715                 720


Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys 
                725                 730                 735


Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu 
            740                 745                 750


Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu 
        755                 760                 765


Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val 
    770                 775                 780


Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn 
785                 790                 795                 800


Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu 
                805                 810                 815


Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu 
            820                 825                 830


Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val 
        835                 840                 845


Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro 
    850                 855                 860


Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr 
865                 870                 875                 880


Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala 
                885                 890                 895


Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe 
            900                 905                 910


Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val 
        915                 920                 925


Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln 
    930                 935                 940


Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly 
945                 950                 955                 960


Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu 
                965                 970                 975


Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln 
            980                 985                 990


Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg 
        995                 1000                1005


Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala 
    1010                1015                1020


Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe 
1025                1030                1035                1040


Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser 
                1045                1050                1055


Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr 
            1060                1065                1070


Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly 
        1075                1080                1085


Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser 
    1090                1095                1100


Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr 
1105                1110                1115                1120


Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln 
                1125                1130                1135


Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile 
            1140                1145                1150


Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala 
        1155                1160                1165


Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser 
    1170                1175                1180


Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys 
1185                1190                1195                1200


Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp 
                1205                1210                1215


Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr 
            1220                1225                1230


Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu 
        1235                1240                1245


His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly 
    1250                1255                1260


Gln 
1265


<210>  6706
<211>  4425
<212>  DNA
<213>  Homo sapiens

<400>  6706
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg aggaccagtg gaatattcct gcttcacaga   1680

cccacttagc atctgacagc aggtctaaag gagaacccag ggattctggg accctccaga   1740

gccaggaggc caaggctgtg aaaaagacca gtctctttga ggaagacaaa gaagatgatc   1800

tttttgccat tgccaaggac agatacatcc tacctcctat tgttcccgaa gttgtctgtc   1860

aagttttgtg tatggaaagt aattcatacc ttcatcagat ctcaaaagaa gctttacaca   1920

cacaagaaga agttgagcca aaagaagacc cagagagtgt cactcctctt tgaagacgat   1980

gttgatagcg gaggctctct gtttggctct cctcccacat ctgttcctcc tgcaacaaag   2040

aaaaaagaga ctgtctctga ggcaccacct ttgctgttca gcgatgaaga agagaaggag   2100

gcacaacttg gagtgaagtc tgtggataag aaggttgaga gtgccaagga gtcattaaaa   2160

tttgggagaa ctgatgtggc tgagtcagaa aaggaaggac ttttgactag atctgctcag   2220

gaaacagtca agcattctga tttattttct tcatcatccc catgggacaa aggaaccaag   2280

cctagaacca aaactgttct tagcttgttt gatgaggaag aggataaaat ggaagatcaa   2340

aacattatcc aggctccaca gaaagaagta ggaaagggct gcgatcctga tgcccacccc   2400

aagagcacag gtgtcttcca ggatgaagag ctgcttttca gccacaagct ccaaaaggac   2460

aatgacccag atgttgacct ttttgctggc accaaaaaaa ccaagctgtt agagccaagt   2520

gttgggagcc tgtttgggga tgatgaagat gatgatcttt tcagctctgc caagtcccag   2580

cctttggtac aagagaaaaa gagagtagtg aaaaaagacc actctgttaa ctctttcaaa   2640

aaccagaaac atcctgaatc cattcaaggt agtaaagaaa aaggcatatg gaagccggaa   2700

acacctcagg caaatttagc gatcaaccca gcggccttgc tgcccacagc ggcttcccag   2760

atctctgaag taaagcctgt tttgccagaa ttggcttttc cttcatctga acacagaagg   2820

agccacggtc tggaaagtgt gcctgtcctt cccgggagtg gggaggccgg tgtgagtttt   2880

gatcttccag ctcaggcaga caccttacac agtgcaaaca agagccgtgt caagatgaga   2940

gggaagcgta gaccgcagac ccgtgcagct aggcggctgg ctgctcagga gtccagcgag   3000

gctgaggaca tgagcgtccc cagaggaccc attgcacagt gggctgatgg cgccatttcc   3060

ccaaatggcc atcggccaca gctcagagca gccagtggag aagacagcac tgaggaggcc   3120

ctggcagctg ccgctgcacc ttgggaaggt ggtcctgtgc ctggagtgga cacaagcccc   3180

tttgcaaagt ctctgggtca ttccagaggg gaggctgacc tttttgattc tggggacatt   3240

ttttccacgg gcactggatc tcagtccgtg gagagaacaa aacccaaggc aaagatagca   3300

gagaatcctg ccaacccacc agtgggtggt aaagcaaaga gccccatgtt tcctgctcta   3360

ggcgaggcca gcagtgatga tgatctcttt cagtctgcta aaccaaaacc agcaaagaaa   3420

acaaatccct ttcctctcct ggaagatgag gatgacctct ttacagatca gaaagtcaag   3480

aagaatgaga caaaatccag tagtcagcag gatgtcatat taacaacaca agatattttt   3540

gaggatgata tatttgctac ggaagcaatt aaaccctctc agaaaaccag agagaaggag   3600

aaaacattgg aatctaattt atttgatgat aacattgata tctttgctga cttaactgta   3660

aaaccaaaag aaaagtccaa aaagaaagtg gaagccaagt ctatatttga tgatgatatg   3720

gatgacatct tctccactgg tatccaggct aagacaacca aaccaaaaag ccgatctgca   3780

caggccgcac ctgaaccaag atttgaacac aaggtgtcca acatctttga tgatcccctg   3840

aatgcctttg gaggccagta gagcacacag ggtatccaca tgttaccctg cagctacatt   3900

gttgagttag tgatgatatt gtatatgctc atggtcttaa ctggattaca aaaagcaaat   3960

actagaacag ctagctcatc ttttacccaa tgtacttagt atttttctgc actggtttaa   4020

tcatgcttaa tactacaaaa caaaaataaa tatttcacag tggttggttt gttttgtttt   4080

taaaccacag tttgatttag ttagccttgc tggggccata atatgcttca gggtgtgtaa   4140

aagaagaaat ctctttgtgg ctttcatggg cagggaatct cagagatagc aaatgccacc   4200

tgaccagaag tctttgttat atggatggga accctaactt agggcttggg caggggaaag   4260

agaaagaaga tgagagatta tacttcatga gtcttagcaa tatgggagca ggttttcact   4320

gaattctgag ggtgcctctg catgtcctcc aaggcaaagt ttggcaaact gtggcccccc   4380

cactgtcata ttttgttaat aaaattttat tggaacacaa tcaca                   4425


<210>  6707
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6707

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6708
<211>  3987
<212>  DNA
<213>  Homo sapiens

<400>  6708
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg agccaaaaga agacccagag agtgtcactc   1680

ctctttgaag acgatgttga tagcggaggc tctctgtttg gctctcctcc cacatctgtt   1740

cctcctgcaa caaaggaagg acttttgact agatctgctc aggaaacagt caagcattct   1800

gatttatttt cttcatcatc cccatgggac aaaggaacca agcctagaac caaaactgtt   1860

cttagcttgt ttgatgagga agaggataaa atggaagatc aaaacattat ccaggctcca   1920

cagaaagaag taggaaaggg ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc   1980

caggatgaag agctgctttt cagccacaag ctccaaaagg acaatgaccc agatgttgac   2040

ctttttgctg gcaccaaaaa aaccaagctg ttagagccaa gtgttgggag cctgtttggg   2100

gatgatgaag atgatgatct tttcagctct gccaagtccc agcctttggt acaagagaaa   2160

aagagagtag tgaaaaaaga ccactctgtt aactctttca aaaaccagaa acatcctgaa   2220

tccattcaag gtagtaaaga aaaaggcata tggaagccgg aaacacctca ggcaaattta   2280

gcgatcaacc cagcggcctt gctgcccaca gcggcttccc agatctctga agtaaagcct   2340

gttttgccag aattggcttt tccttcatct gaacacagaa ggagccacgg tctggaaagt   2400

gtgcctgtcc ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc agctcaggca   2460

gacaccttac acagtgcaaa caagagccgt gtcaagatga gagggaagcg tagaccgcag   2520

acccgtgcag ctaggcggct ggctgctcag gagtccagcg aggctgagga catgagcgtc   2580

cccagaggac ccattgcaca gtgggctgat ggcgccattt ccccaaatgg ccatcggcca   2640

cagctcagag cagccagtgg agaagacagc actgaggagg ccctggcagc tgccgctgca   2700

ccttgggaag gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa gtctctgggt   2760

cattccagag gggaggctga cctttttgat tctggggaca ttttttccac gggcactgga   2820

tctcagtccg tggagagaac aaaacccaag gcaaagatag cagagaatcc tgccaaccca   2880

ccagtgggtg gtaaagcaaa gagccccatg tttcctgctc taggcgaggc cagcagtgat   2940

gatgatctct ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc ctttcctctc   3000

ctggaagatg aggatgacct ctttacagat cagaaagtca agaagaatga gacaaaatcc   3060

agtagtcagc aggatgtcat attaacaaca caagatattt ttgaggatga tatatttgct   3120

acggaagcaa ttaaaccctc tcagaaaacc agagagaagg agaaaacatt ggaatctaat   3180

ttatttgatg ataacattga tatctttgct gacttaactg taaaaccaaa agaaaagtcc   3240

aaaaagaaag tggaagccaa gtctatattt gatgatgata tggatgacat cttctccact   3300

ggtatccagg ctaagacaac caaaccaaaa agccgatctg cacaggccgc acctgaacca   3360

agatttgaac acaaggtgtc caacatcttt gatgatcccc tgaatgcctt tggaggccag   3420

tagagcacac agggtatcca catgttaccc tgcagctaca ttgttgagtt agtgatgata   3480

ttgtatatgc tcatggtctt aactggatta caaaaagcaa atactagaac agctagctca   3540

tcttttaccc aatgtactta gtatttttct gcactggttt aatcatgctt aatactacaa   3600

aacaaaaata aatatttcac agtggttggt ttgttttgtt tttaaaccac agtttgattt   3660

agttagcctt gctggggcca taatatgctt cagggtgtgt aaaagaagaa atctctttgt   3720

ggctttcatg ggcagggaat ctcagagata gcaaatgcca cctgaccaga agtctttgtt   3780

atatggatgg gaaccctaac ttagggcttg ggcaggggaa agagaaagaa gatgagagat   3840

tatacttcat gagtcttagc aatatgggag caggttttca ctgaattctg agggtgcctc   3900

tgcatgtcct ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca tattttgtta   3960

ataaaatttt attggaacac aatcaca                                       3987


<210>  6709
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6709

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6710
<211>  4449
<212>  DNA
<213>  Homo sapiens

<400>  6710
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggatttgtt ttcttctcaa agtgcgagta acttaaaagg tgcatctctg ctgcctggca   1500

agctccccac gtcggtttcc ctgtttgatg atgaagatga agaggataat ctttttgggg   1560

gtacagctgc taagaagcag acattgtctc tacaagctca gagagaagag aaagcaaaag   1620

cctccgagct ctccaaaaag aaagcatctg ccctgttgtt cagcagtgat gaggaggacc   1680

agtggaatat tcctgcttca cagacccact tagcatctga cagcaggtct aaaggagaac   1740

ccagggattc tgggaccctc cagagccagg aggccaaggc tgtgaaaaag accagtctct   1800

ttgaggaaga caaagaagat gatctttttg ccattgccaa ggacagatac atcctacctc   1860

ctattgttcc cgaagttgtc tgtcaagttt tgtgtatgga aagtaattca taccttcatc   1920

agatctcaaa agaagcttta cacacacaag aagaagttga gccaaaagaa gacccagaga   1980

gtgtcactcc tctttgaaga cgatgttgat agcggaggct ctctgtttgg ctctcctccc   2040

acatctgttc ctcctgcaac aaagaaaaaa gagactgtct ctgaggcacc acctttgctg   2100

ttcagcgatg aagaagagaa ggaggcacaa cttggagtga agtctgtgga taagaaggtt   2160

gagagtgcca aggagtcatt aaaatttggg agaactgatg tggctgagtc agaaaaggaa   2220

ggacttttga ctagatctgc tcaggaaaca gtcaagcatt ctgatttatt ttcttcatca   2280

tccccatggg acaaaggaac caagcctaga accaaaactg ttcttagctt gtttgatgag   2340

gaagaggata aaatggaaga tcaaaacatt atccaggctc cacagaaaga agtaggaaag   2400

ggctgcgatc ctgatgccca ccccaagagc acaggtgtct tccaggatga agagctgctt   2460

ttcagccaca agctccaaaa ggacaatgac ccagatgttg acctttttgc tggcaccaaa   2520

aaaaccaagc tgttagagcc aagtgttggg agcctgtttg gggatgatga agatgatgat   2580

cttttcagct ctgccaagtc ccagcctttg gtacaagaga aaaagagagt agtgaaaaaa   2640

gaccactctg ttaactcttt caaaaaccag aaacatcctg aatccattca aggtagtaaa   2700

gaaaaaggca tatggaagcc ggaaacacct caggcaaatt tagcgatcaa cccagcggcc   2760

ttgctgccca cagcggcttc ccagatctct gaagtaaagc ctgttttgcc agaattggct   2820

tttccttcat ctgaacacag aaggagccac ggtctggaaa gtgtgcctgt ccttcccggg   2880

agtggggagg ccggtgtgag ttttgatctt ccagctcagg cagacacctt acacagtgca   2940

aacaagagcc gtgtcaagat gagagggaag cgtagaccgc agacccgtgc agctaggcgg   3000

ctggctgctc aggagtccag cgaggctgag gacatgagcg tccccagagg acccattgca   3060

cagtgggctg atggcgccat ttccccaaat ggccatcggc cacagctcag agcagccagt   3120

ggagaagaca gcactgagga ggccctggca gctgccgctg caccttggga aggtggtcct   3180

gtgcctggag tggacacaag cccctttgca aagtctctgg gtcattccag aggggaggct   3240

gacctttttg attctgggga cattttttcc acgggcactg gatctcagtc cgtggagaga   3300

acaaaaccca aggcaaagat agcagagaat cctgccaacc caccagtggg tggtaaagca   3360

aagagcccca tgtttcctgc tctaggcgag gccagcagtg atgatgatct ctttcagtct   3420

gctaaaccaa aaccagcaaa gaaaacaaat ccctttcctc tcctggaaga tgaggatgac   3480

ctctttacag atcagaaagt caagaagaat gagacaaaat ccagtagtca gcaggatgtc   3540

atattaacaa cacaagatat ttttgaggat gatatatttg ctacggaagc aattaaaccc   3600

tctcagaaaa ccagagagaa ggagaaaaca ttggaatcta atttatttga tgataacatt   3660

gatatctttg ctgacttaac tgtaaaacca aaagaaaagt ccaaaaagaa agtggaagcc   3720

aagtctatat ttgatgatga tatggatgac atcttctcca ctggtatcca ggctaagaca   3780

accaaaccaa aaagccgatc tgcacaggcc gcacctgaac caagatttga acacaaggtg   3840

tccaacatct ttgatgatcc cctgaatgcc tttggaggcc agtagagcac acagggtatc   3900

cacatgttac cctgcagcta cattgttgag ttagtgatga tattgtatat gctcatggtc   3960

ttaactggat tacaaaaagc aaatactaga acagctagct catcttttac ccaatgtact   4020

tagtattttt ctgcactggt ttaatcatgc ttaatactac aaaacaaaaa taaatatttc   4080

acagtggttg gtttgttttg tttttaaacc acagtttgat ttagttagcc ttgctggggc   4140

cataatatgc ttcagggtgt gtaaaagaag aaatctcttt gtggctttca tgggcaggga   4200

atctcagaga tagcaaatgc cacctgacca gaagtctttg ttatatggat gggaacccta   4260

acttagggct tgggcagggg aaagagaaag aagatgagag attatacttc atgagtctta   4320

gcaatatggg agcaggtttt cactgaattc tgagggtgcc tctgcatgtc ctccaaggca   4380

aagtttggca aactgtggcc cccccactgt catattttgt taataaaatt ttattggaac   4440

acaatcaca                                                           4449


<210>  6711
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6711

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6712
<211>  4599
<212>  DNA
<213>  Homo sapiens

<400>  6712
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gaggaccagt ggaatattcc tgcttcacag acccacttag   1800

catctgacag caggtctaaa ggagaaccca gggattctgg gaccctccag agccaggagg   1860

ccaaggctgt gaaaaagacc agtctctttg aggaagacaa agaagatgat ctttttgcca   1920

ttgccaagga cagatacatc ctacctccta ttgttcccga agttgtctgt caagttttgt   1980

gtatggaaag taattcatac cttcatcaga tctcaaaaga agctttacac acacaagaag   2040

aagttgagcc aaaagaagac ccagagagtg tcactcctct ttgaagacga tgttgatagc   2100

ggaggctctc tgtttggctc tcctcccaca tctgttcctc ctgcaacaaa gaaaaaagag   2160

actgtctctg aggcaccacc tttgctgttc agcgatgaag aagagaagga ggcacaactt   2220

ggagtgaagt ctgtggataa gaaggttgag agtgccaagg agtcattaaa atttgggaga   2280

actgatgtgg ctgagtcaga aaaggaagga cttttgacta gatctgctca ggaaacagtc   2340

aagcattctg atttattttc ttcatcatcc ccatgggaca aaggaaccaa gcctagaacc   2400

aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa tggaagatca aaacattatc   2460

caggctccac agaaagaagt aggaaagggc tgcgatcctg atgcccaccc caagagcaca   2520

ggtgtcttcc aggatgaaga gctgcttttc agccacaagc tccaaaagga caatgaccca   2580

gatgttgacc tttttgctgg caccaaaaaa accaagctgt tagagccaag tgttgggagc   2640

ctgtttgggg atgatgaaga tgatgatctt ttcagctctg ccaagtccca gcctttggta   2700

caagagaaaa agagagtagt gaaaaaagac cactctgtta actctttcaa aaaccagaaa   2760

catcctgaat ccattcaagg tagtaaagaa aaaggcatat ggaagccgga aacacctcag   2820

gactcatcag gtctcgctcc atttaaaacc aaagaaccat ccactcggat cgggaagata   2880

caagcaaatt tagcgatcaa cccagcggcc ttgctgccca cagcggcttc ccagatctct   2940

gaagtaaagc ctgttttgcc agaattggct tttccttcat ctgaacacag aaggagccac   3000

ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg ccggtgtgag ttttgatctt   3060

ccagctcagg cagacacctt acacagtgca aacaagagcc gtgtcaagat gagagggaag   3120

cgtagaccgc agacccgtgc agctaggcgg ctggctgctc aggagtccag cgaggctgag   3180

gacatgagcg tccccagagg acccattgca cagtgggctg atggcgccat ttccccaaat   3240

ggccatcggc cacagctcag agcagccagt ggagaagaca gcactgagga ggccctggca   3300

gctgccgctg caccttggga aggtggtcct gtgcctggag tggacacaag cccctttgca   3360

aagtctctgg gtcattccag aggggaggct gacctttttg attctgggga cattttttcc   3420

acgggcactg gatctcagtc cgtggagaga acaaaaccca aggcaaagat agcagagaat   3480

cctgccaacc caccagtggg tggtaaagca aagagcccca tgtttcctgc tctaggcgag   3540

gccagcagtg atgatgatct ctttcagtct gctaaaccaa aaccagcaaa gaaaacaaat   3600

ccctttcctc tcctggaaga tgaggatgac ctctttacag atcagaaagt caagaagaat   3660

gagacaaaat ccagtagtca gcaggatgtc atattaacaa cacaagatat ttttgaggat   3720

gatatatttg ctacggaagc aattaaaccc tctcagaaaa ccagagagaa ggagaaaaca   3780

ttggaatcta atttatttga tgataacatt gatatctttg ctgacttaac tgtaaaacca   3840

aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat ttgatgatga tatggatgac   3900

atcttctcca ctggtatcca ggctaagaca accaaaccaa aaagccgatc tgcacaggcc   3960

gcacctgaac caagatttga acacaaggtg tccaacatct ttgatgatcc cctgaatgcc   4020

tttggaggcc agtagagcac acagggtatc cacatgttac cctgcagcta cattgttgag   4080

ttagtgatga tattgtatat gctcatggtc ttaactggat tacaaaaagc aaatactaga   4140

acagctagct catcttttac ccaatgtact tagtattttt ctgcactggt ttaatcatgc   4200

ttaatactac aaaacaaaaa taaatatttc acagtggttg gtttgttttg tttttaaacc   4260

acagtttgat ttagttagcc ttgctggggc cataatatgc ttcagggtgt gtaaaagaag   4320

aaatctcttt gtggctttca tgggcaggga atctcagaga tagcaaatgc cacctgacca   4380

gaagtctttg ttatatggat gggaacccta acttagggct tgggcagggg aaagagaaag   4440

aagatgagag attatacttc atgagtctta gcaatatggg agcaggtttt cactgaattc   4500

tgagggtgcc tctgcatgtc ctccaaggca aagtttggca aactgtggcc cccccactgt   4560

catattttgt taataaaatt ttattggaac acaatcaca                          4599


<210>  6713
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6713

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6714
<211>  4223
<212>  DNA
<213>  Homo sapiens

<400>  6714
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggatttgttt tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc   1380

tgcctggcaa gctccccacg tcggtttccc tgtttgatga tgaagatgaa gaggataatc   1440

tttttggggg tacagctgct aagaagcaga cattgtctct acaagctcag agagaagaga   1500

aagcaaaagc ctccgagctc tccaaaaaga aagcatctgc cctgttgttc agcagtgatg   1560

aggaggacca gtggaatatt cctgcttcac agacccactt agcatctgac agcaggtcta   1620

aaggagaacc cagggattct gggaccctcc agagccagga ggccaaggct gtgaaaaaga   1680

ccagtctctt tgaggaagac aaagaagatg atctttttgc cattgccaag gacagccaaa   1740

agaagaccca gagagtgtca ctcctctttg aagacgatgt tgatagcgga ggctctctgt   1800

ttggctctcc tcccacatct gttcctcctg caacaaagaa aaaagagact gtctctgagg   1860

caccaccttt gctgttcagc gatgaagaag agaaggaggc acaacttgga gtgaagtctg   1920

tggataagaa ggttgagagt gccaaggagt cattaaaatt tgggagaact gatgtggctg   1980

agtcagaaaa ggaaggactt ttgactagat ctgctcagga aacagtcaag cattctgatt   2040

tattttcttc atcatcccca tgggacaaag gaaccaagcc tagaaccaaa actgttctta   2100

gcttgtttga tgaggaagag gataaaatgg aagatcaaaa cattatccag gctccacaga   2160

aagaagtagg aaagggctgc gatcctgatg cccaccccaa gagcacaggt gtcttccagg   2220

atgaagagct gcttttcagc cacaagctcc aaaaggacaa tgacccagat gttgaccttt   2280

ttgctggcac caaaaaaacc aagctgttag agccaagtgt tgggagcctg tttggggatg   2340

atgaagatga tgatcttttc agctctgcca agtcccagcc tttggtacaa gagaaaaaga   2400

gagtagtgaa aaaagaccac tctgttaact ctttcaaaaa ccagaaacat cctgaatcca   2460

ttcaaggtag taaagaaaaa ggcatatgga agccggaaac acctcaggca aatttagcga   2520

tcaacccagc ggccttgctg cccacagcgg cttcccagat ctctgaagta aagcctgttt   2580

tgccagaatt ggcttttcct tcatctgaac acagaaggag ccacggtctg gaaagtgtgc   2640

ctgtccttcc cgggagtggg gaggccggtg tgagttttga tcttccagct caggcagaca   2700

ccttacacag tgcaaacaag agccgtgtca agatgagagg gaagcgtaga ccgcagaccc   2760

gtgcagctag gcggctggct gctcaggagt ccagcgaggc tgaggacatg agcgtcccca   2820

gaggacccat tgcacagtgg gctgatggcg ccatttcccc aaatggccat cggccacagc   2880

tcagagcagc cagtggagaa gacagcactg aggaggccct ggcagctgcc gctgcacctt   2940

gggaaggtgg tcctgtgcct ggagtggaca caagcccctt tgcaaagtct ctgggtcatt   3000

ccagagggga ggctgacctt tttgattctg gggacatttt ttccacgggc actggatctc   3060

agtccgtgga gagaacaaaa cccaaggcaa agatagcaga gaatcctgcc aacccaccag   3120

tgggtggtaa agcaaagagc cccatgtttc ctgctctagg cgaggccagc agtgatgatg   3180

atctctttca gtctgctaaa ccaaaaccag caaagaaaac aaatcccttt cctctcctgg   3240

aagatgagga tgacctcttt acagatcaga aagtcaagaa gaatgagaca aaatccagta   3300

gtcagcagga tgtcatatta acaacacaag atatttttga ggatgatata tttgctacgg   3360

aagcaattaa accctctcag aaaaccagag agaaggagaa aacattggaa tctaatttat   3420

ttgatgataa cattgatatc tttgctgact taactgtaaa accaaaagaa aagtccaaaa   3480

agaaagtgga agccaagtct atatttgatg atgatatgga tgacatcttc tccactggta   3540

tccaggctaa gacaaccaaa ccaaaaagcc gatctgcaca ggccgcacct gaaccaagat   3600

ttgaacacaa ggtgtccaac atctttgatg atcccctgaa tgcctttgga ggccagtaga   3660

gcacacaggg tatccacatg ttaccctgca gctacattgt tgagttagtg atgatattgt   3720

atatgctcat ggtcttaact ggattacaaa aagcaaatac tagaacagct agctcatctt   3780

ttacccaatg tacttagtat ttttctgcac tggtttaatc atgcttaata ctacaaaaca   3840

aaaataaata tttcacagtg gttggtttgt tttgttttta aaccacagtt tgatttagtt   3900

agccttgctg gggccataat atgcttcagg gtgtgtaaaa gaagaaatct ctttgtggct   3960

ttcatgggca gggaatctca gagatagcaa atgccacctg accagaagtc tttgttatat   4020

ggatgggaac cctaacttag ggcttgggca ggggaaagag aaagaagatg agagattata   4080

cttcatgagt cttagcaata tgggagcagg ttttcactga attctgaggg tgcctctgca   4140

tgtcctccaa ggcaaagttt ggcaaactgt ggccccccca ctgtcatatt ttgttaataa   4200

aattttattg gaacacaatc aca                                           4223


<210>  6715
<211>  1199
<212>  PRT
<213>  Homo sapiens

<400>  6715

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln Lys Arg Ser 
            180                 185                 190


Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp 
        195                 200                 205


Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu 
    210                 215                 220


Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro 
225                 230                 235                 240


Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp 
                245                 250                 255


Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly 
            260                 265                 270


Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu 
        275                 280                 285


Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser 
    290                 295                 300


Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe 
305                 310                 315                 320


Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys 
                325                 330                 335


Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly 
            340                 345                 350


Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp 
        355                 360                 365


Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val 
    370                 375                 380


Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys 
385                 390                 395                 400


Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu 
                405                 410                 415


Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala 
            420                 425                 430


Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser 
        435                 440                 445


Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly 
    450                 455                 460


Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu 
465                 470                 475                 480


Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu 
                485                 490                 495


Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr 
            500                 505                 510


His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly 
        515                 520                 525


Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe 
    530                 535                 540


Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln 
545                 550                 555                 560


Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser 
                565                 570                 575


Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr 
            580                 585                 590


Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp 
        595                 600                 605


Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys 
    610                 615                 620


Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala 
625                 630                 635                 640


Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                645                 650                 655


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            660                 665                 670


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        675                 680                 685


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    690                 695                 700


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
705                 710                 715                 720


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                725                 730                 735


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            740                 745                 750


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        755                 760                 765


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    770                 775                 780


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
785                 790                 795                 800


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                805                 810                 815


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            820                 825                 830


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        835                 840                 845


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    850                 855                 860


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
865                 870                 875                 880


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                885                 890                 895


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            900                 905                 910


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        915                 920                 925


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    930                 935                 940


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
945                 950                 955                 960


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                965                 970                 975


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            980                 985                 990


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        995                 1000                1005


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    1010                1015                1020


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
1025                1030                1035                1040


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                1045                1050                1055


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            1060                1065                1070


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        1075                1080                1085


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    1090                1095                1100


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
1105                1110                1115                1120


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                1125                1130                1135


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            1140                1145                1150


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        1155                1160                1165


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    1170                1175                1180


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
1185                1190                1195


<210>  6716
<211>  4488
<212>  DNA
<213>  Homo sapiens

<400>  6716
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg aggaccagtg gaatattcct gcttcacaga   1680

cccacttagc atctgacagc aggtctaaag gagaacccag ggattctggg accctccaga   1740

gccaggaggc caaggctgtg aaaaagacca gtctctttga ggaagacaaa gaagatgatc   1800

tttttgccat tgccaaggac agatacatcc tacctcctat tgttcccgaa gttgtctgtc   1860

aagttttgtg tatggaaagt aattcatacc ttcatcagat ctcaaaagaa gctttacaca   1920

cacaagaaga agttgagcca aaagaagacc cagagagtgt cactcctctt tgaagacgat   1980

gttgatagcg gaggctctct gtttggctct cctcccacat ctgttcctcc tgcaacaaag   2040

aaaaaagaga ctgtctctga ggcaccacct ttgctgttca gcgatgaaga agagaaggag   2100

gcacaacttg gagtgaagtc tgtggataag aaggttgaga gtgccaagga gtcattaaaa   2160

tttgggagaa ctgatgtggc tgagtcagaa aaggaaggac ttttgactag atctgctcag   2220

gaaacagtca agcattctga tttattttct tcatcatccc catgggacaa aggaaccaag   2280

cctagaacca aaactgttct tagcttgttt gatgaggaag aggataaaat ggaagatcaa   2340

aacattatcc aggctccaca gaaagaagta ggaaagggct gcgatcctga tgcccacccc   2400

aagagcacag gtgtcttcca ggatgaagag ctgcttttca gccacaagct ccaaaaggac   2460

aatgacccag atgttgacct ttttgctggc accaaaaaaa ccaagctgtt agagccaagt   2520

gttgggagcc tgtttgggga tgatgaagat gatgatcttt tcagctctgc caagtcccag   2580

cctttggtac aagagaaaaa gagagtagtg aaaaaagacc actctgttaa ctctttcaaa   2640

aaccagaaac atcctgaatc cattcaaggt agtaaagaaa aaggcatatg gaagccggaa   2700

acacctcagg actcatcagg tctcgctcca tttaaaacca aagaaccatc cactcggatc   2760

gggaagatac aagcaaattt agcgatcaac ccagcggcct tgctgcccac agcggcttcc   2820

cagatctctg aagtaaagcc tgttttgcca gaattggctt ttccttcatc tgaacacaga   2880

aggagccacg gtctggaaag tgtgcctgtc cttcccggga gtggggaggc cggtgtgagt   2940

tttgatcttc cagctcaggc agacacctta cacagtgcaa acaagagccg tgtcaagatg   3000

agagggaagc gtagaccgca gacccgtgca gctaggcggc tggctgctca ggagtccagc   3060

gaggctgagg acatgagcgt ccccagagga cccattgcac agtgggctga tggcgccatt   3120

tccccaaatg gccatcggcc acagctcaga gcagccagtg gagaagacag cactgaggag   3180

gccctggcag ctgccgctgc accttgggaa ggtggtcctg tgcctggagt ggacacaagc   3240

ccctttgcaa agtctctggg tcattccaga ggggaggctg acctttttga ttctggggac   3300

attttttcca cgggcactgg atctcagtcc gtggagagaa caaaacccaa ggcaaagata   3360

gcagagaatc ctgccaaccc accagtgggt ggtaaagcaa agagccccat gtttcctgct   3420

ctaggcgagg ccagcagtga tgatgatctc tttcagtctg ctaaaccaaa accagcaaag   3480

aaaacaaatc cctttcctct cctggaagat gaggatgacc tctttacaga tcagaaagtc   3540

aagaagaatg agacaaaatc cagtagtcag caggatgtca tattaacaac acaagatatt   3600

tttgaggatg atatatttgc tacggaagca attaaaccct ctcagaaaac cagagagaag   3660

gagaaaacat tggaatctaa tttatttgat gataacattg atatctttgc tgacttaact   3720

gtaaaaccaa aagaaaagtc caaaaagaaa gtggaagcca agtctatatt tgatgatgat   3780

atggatgaca tcttctccac tggtatccag gctaagacaa ccaaaccaaa aagccgatct   3840

gcacaggccg cacctgaacc aagatttgaa cacaaggtgt ccaacatctt tgatgatccc   3900

ctgaatgcct ttggaggcca gtagagcaca cagggtatcc acatgttacc ctgcagctac   3960

attgttgagt tagtgatgat attgtatatg ctcatggtct taactggatt acaaaaagca   4020

aatactagaa cagctagctc atcttttacc caatgtactt agtatttttc tgcactggtt   4080

taatcatgct taatactaca aaacaaaaat aaatatttca cagtggttgg tttgttttgt   4140

ttttaaacca cagtttgatt tagttagcct tgctggggcc ataatatgct tcagggtgtg   4200

taaaagaaga aatctctttg tggctttcat gggcagggaa tctcagagat agcaaatgcc   4260

acctgaccag aagtctttgt tatatggatg ggaaccctaa cttagggctt gggcagggga   4320

aagagaaaga agatgagaga ttatacttca tgagtcttag caatatggga gcaggttttc   4380

actgaattct gagggtgcct ctgcatgtcc tccaaggcaa agtttggcaa actgtggccc   4440

ccccactgtc atattttgtt aataaaattt tattggaaca caatcaca                4488


<210>  6717
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6717

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6718
<211>  4286
<212>  DNA
<213>  Homo sapiens

<400>  6718
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggatttgttt tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc   1380

tgcctggcaa gctccccacg tcggtttccc tgtttgatga tgaagatgaa gaggataatc   1440

tttttggggg tacagctgct aagaagcaga cattgtctct acaagctcag agagaagaga   1500

aagcaaaagc ctccgagctc tccaaaaaga aagcatctgc cctgttgttc agcagtgatg   1560

aggaggacca gtggaatatt cctgcttcac agacccactt agcatctgac agcaggtcta   1620

aaggagaacc cagggattct gggaccctcc agagccagga ggccaaggct gtgaaaaaga   1680

ccagtctctt tgaggaagac aaagaagatg atctttttgc cattgccaag gacagccaaa   1740

agaagaccca gagagtgtca ctcctctttg aagacgatgt tgatagcgga ggctctctgt   1800

ttggctctcc tcccacatct gttcctcctg caacaaagaa aaaagagact gtctctgagg   1860

caccaccttt gctgttcagc gatgaagaag agaaggaggc acaacttgga gtgaagtctg   1920

tggataagaa ggttgagagt gccaaggagt cattaaaatt tgggagaact gatgtggctg   1980

agtcagaaaa ggaaggactt ttgactagat ctgctcagga aacagtcaag cattctgatt   2040

tattttcttc atcatcccca tgggacaaag gaaccaagcc tagaaccaaa actgttctta   2100

gcttgtttga tgaggaagag gataaaatgg aagatcaaaa cattatccag gctccacaga   2160

aagaagtagg aaagggctgc gatcctgatg cccaccccaa gagcacaggt gtcttccagg   2220

atgaagagct gcttttcagc cacaagctcc aaaaggacaa tgacccagat gttgaccttt   2280

ttgctggcac caaaaaaacc aagctgttag agccaagtgt tgggagcctg tttggggatg   2340

atgaagatga tgatcttttc agctctgcca agtcccagcc tttggtacaa gagaaaaaga   2400

gagtagtgaa aaaagaccac tctgttaact ctttcaaaaa ccagaaacat cctgaatcca   2460

ttcaaggtag taaagaaaaa ggcatatgga agccggaaac acctcaggac tcatcaggtc   2520

tcgctccatt taaaaccaaa gaaccatcca ctcggatcgg gaagatacaa gcaaatttag   2580

cgatcaaccc agcggccttg ctgcccacag cggcttccca gatctctgaa gtaaagcctg   2640

ttttgccaga attggctttt ccttcatctg aacacagaag gagccacggt ctggaaagtg   2700

tgcctgtcct tcccgggagt ggggaggccg gtgtgagttt tgatcttcca gctcaggcag   2760

acaccttaca cagtgcaaac aagagccgtg tcaagatgag agggaagcgt agaccgcaga   2820

cccgtgcagc taggcggctg gctgctcagg agtccagcga ggctgaggac atgagcgtcc   2880

ccagaggacc cattgcacag tgggctgatg gcgccatttc cccaaatggc catcggccac   2940

agctcagagc agccagtgga gaagacagca ctgaggaggc cctggcagct gccgctgcac   3000

cttgggaagg tggtcctgtg cctggagtgg acacaagccc ctttgcaaag tctctgggtc   3060

attccagagg ggaggctgac ctttttgatt ctggggacat tttttccacg ggcactggat   3120

ctcagtccgt ggagagaaca aaacccaagg caaagatagc agagaatcct gccaacccac   3180

cagtgggtgg taaagcaaag agccccatgt ttcctgctct aggcgaggcc agcagtgatg   3240

atgatctctt tcagtctgct aaaccaaaac cagcaaagaa aacaaatccc tttcctctcc   3300

tggaagatga ggatgacctc tttacagatc agaaagtcaa gaagaatgag acaaaatcca   3360

gtagtcagca ggatgtcata ttaacaacac aagatatttt tgaggatgat atatttgcta   3420

cggaagcaat taaaccctct cagaaaacca gagagaagga gaaaacattg gaatctaatt   3480

tatttgatga taacattgat atctttgctg acttaactgt aaaaccaaaa gaaaagtcca   3540

aaaagaaagt ggaagccaag tctatatttg atgatgatat ggatgacatc ttctccactg   3600

gtatccaggc taagacaacc aaaccaaaaa gccgatctgc acaggccgca cctgaaccaa   3660

gatttgaaca caaggtgtcc aacatctttg atgatcccct gaatgccttt ggaggccagt   3720

agagcacaca gggtatccac atgttaccct gcagctacat tgttgagtta gtgatgatat   3780

tgtatatgct catggtctta actggattac aaaaagcaaa tactagaaca gctagctcat   3840

cttttaccca atgtacttag tatttttctg cactggttta atcatgctta atactacaaa   3900

acaaaaataa atatttcaca gtggttggtt tgttttgttt ttaaaccaca gtttgattta   3960

gttagccttg ctggggccat aatatgcttc agggtgtgta aaagaagaaa tctctttgtg   4020

gctttcatgg gcagggaatc tcagagatag caaatgccac ctgaccagaa gtctttgtta   4080

tatggatggg aaccctaact tagggcttgg gcaggggaaa gagaaagaag atgagagatt   4140

atacttcatg agtcttagca atatgggagc aggttttcac tgaattctga gggtgcctct   4200

gcatgtcctc caaggcaaag tttggcaaac tgtggccccc ccactgtcat attttgttaa   4260

taaaatttta ttggaacaca atcaca                                        4286


<210>  6719
<211>  1220
<212>  PRT
<213>  Homo sapiens

<400>  6719

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln Lys Arg Ser 
            180                 185                 190


Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp 
        195                 200                 205


Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu 
    210                 215                 220


Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro 
225                 230                 235                 240


Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp 
                245                 250                 255


Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly 
            260                 265                 270


Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu 
        275                 280                 285


Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser 
    290                 295                 300


Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe 
305                 310                 315                 320


Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys 
                325                 330                 335


Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly 
            340                 345                 350


Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp 
        355                 360                 365


Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val 
    370                 375                 380


Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys 
385                 390                 395                 400


Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu 
                405                 410                 415


Asn Lys Ala Arg Ala Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala 
            420                 425                 430


Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser 
        435                 440                 445


Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly 
    450                 455                 460


Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu 
465                 470                 475                 480


Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu 
                485                 490                 495


Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr 
            500                 505                 510


His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly 
        515                 520                 525


Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe 
    530                 535                 540


Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln 
545                 550                 555                 560


Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser 
                565                 570                 575


Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr 
            580                 585                 590


Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp 
        595                 600                 605


Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys 
    610                 615                 620


Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala 
625                 630                 635                 640


Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                645                 650                 655


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            660                 665                 670


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        675                 680                 685


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    690                 695                 700


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
705                 710                 715                 720


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                725                 730                 735


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            740                 745                 750


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        755                 760                 765


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    770                 775                 780


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
785                 790                 795                 800


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                805                 810                 815


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            820                 825                 830


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        835                 840                 845


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    850                 855                 860


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
865                 870                 875                 880


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                885                 890                 895


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            900                 905                 910


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        915                 920                 925


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    930                 935                 940


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
945                 950                 955                 960


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                965                 970                 975


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            980                 985                 990


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        995                 1000                1005


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    1010                1015                1020


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
1025                1030                1035                1040


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                1045                1050                1055


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            1060                1065                1070


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        1075                1080                1085


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    1090                1095                1100


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
1105                1110                1115                1120


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                1125                1130                1135


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            1140                1145                1150


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        1155                1160                1165


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    1170                1175                1180


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
1185                1190                1195                1200


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                1205                1210                1215


Phe Gly Gly Gln 
            1220


<210>  6720
<211>  4338
<212>  DNA
<213>  Homo sapiens

<400>  6720
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggatttgttt tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc   1380

tgcctggcaa gctccccacg tcggtttccc tgtttgatga tgaagatgaa gaggataatc   1440

tttttggggg tacagctgct aagaagcaga cattgtctct acaagctcag agagaagaga   1500

aagcaaaagc ctccgagctc tccaaaaaga aagcatctgc cctgttgttc agcagtgatg   1560

aggaggacca gtggaatatt cctgcttcac agacccactt agcatctgac agcaggtcta   1620

aaggagaacc cagggattct gggaccctcc agagccagga ggccaaggct gtgaaaaaga   1680

ccagtctctt tgaggaagac aaagaagatg atctttttgc cattgccaag gacagataca   1740

tcctacctcc tattgttccc gaagttgtct gtcaagtttt gtgtatggaa agtaattcat   1800

accttcatca gatctcaaaa gaagctttac acacacaaga agaagttgag ccaaaagaag   1860

acccagagag tgtcactcct ctttgaagac gatgttgata gcggaggctc tctgtttggc   1920

tctcctccca catctgttcc tcctgcaaca aagaaaaaag agactgtctc tgaggcacca   1980

cctttgctgt tcagcgatga agaagagaag gaggcacaac ttggagtgaa gtctgtggat   2040

aagaaggttg agagtgccaa ggagtcatta aaatttggga gaactgatgt ggctgagtca   2100

gaaaaggaag gacttttgac tagatctgct caggaaacag tcaagcattc tgatttattt   2160

tcttcatcat ccccatggga caaaggaacc aagcctagaa ccaaaactgt tcttagcttg   2220

tttgatgagg aagaggataa aatggaagat caaaacatta tccaggctcc acagaaagaa   2280

gtaggaaagg gctgcgatcc tgatgcccac cccaagagca caggtgtctt ccaggatgaa   2340

gagctgcttt tcagccacaa gctccaaaag gacaatgacc cagatgttga cctttttgct   2400

ggcaccaaaa aaaccaagct gttagagcca agtgttggga gcctgtttgg ggatgatgaa   2460

gatgatgatc ttttcagctc tgccaagtcc cagcctttgg tacaagagaa aaagagagta   2520

gtgaaaaaag accactctgt taactctttc aaaaaccaga aacatcctga atccattcaa   2580

ggtagtaaag aaaaaggcat atggaagccg gaaacacctc aggcaaattt agcgatcaac   2640

ccagcggcct tgctgcccac agcggcttcc cagatctctg aagtaaagcc tgttttgcca   2700

gaattggctt ttccttcatc tgaacacaga aggagccacg gtctggaaag tgtgcctgtc   2760

cttcccggga gtggggaggc cggtgtgagt tttgatcttc cagctcaggc agacacctta   2820

cacagtgcaa acaagagccg tgtcaagatg agagggaagc gtagaccgca gacccgtgca   2880

gctaggcggc tggctgctca ggagtccagc gaggctgagg acatgagcgt ccccagagga   2940

cccattgcac agtgggctga tggcgccatt tccccaaatg gccatcggcc acagctcaga   3000

gcagccagtg gagaagacag cactgaggag gccctggcag ctgccgctgc accttgggaa   3060

ggtggtcctg tgcctggagt ggacacaagc ccctttgcaa agtctctggg tcattccaga   3120

ggggaggctg acctttttga ttctggggac attttttcca cgggcactgg atctcagtcc   3180

gtggagagaa caaaacccaa ggcaaagata gcagagaatc ctgccaaccc accagtgggt   3240

ggtaaagcaa agagccccat gtttcctgct ctaggcgagg ccagcagtga tgatgatctc   3300

tttcagtctg ctaaaccaaa accagcaaag aaaacaaatc cctttcctct cctggaagat   3360

gaggatgacc tctttacaga tcagaaagtc aagaagaatg agacaaaatc cagtagtcag   3420

caggatgtca tattaacaac acaagatatt tttgaggatg atatatttgc tacggaagca   3480

attaaaccct ctcagaaaac cagagagaag gagaaaacat tggaatctaa tttatttgat   3540

gataacattg atatctttgc tgacttaact gtaaaaccaa aagaaaagtc caaaaagaaa   3600

gtggaagcca agtctatatt tgatgatgat atggatgaca tcttctccac tggtatccag   3660

gctaagacaa ccaaaccaaa aagccgatct gcacaggccg cacctgaacc aagatttgaa   3720

cacaaggtgt ccaacatctt tgatgatccc ctgaatgcct ttggaggcca gtagagcaca   3780

cagggtatcc acatgttacc ctgcagctac attgttgagt tagtgatgat attgtatatg   3840

ctcatggtct taactggatt acaaaaagca aatactagaa cagctagctc atcttttacc   3900

caatgtactt agtatttttc tgcactggtt taatcatgct taatactaca aaacaaaaat   3960

aaatatttca cagtggttgg tttgttttgt ttttaaacca cagtttgatt tagttagcct   4020

tgctggggcc ataatatgct tcagggtgtg taaaagaaga aatctctttg tggctttcat   4080

gggcagggaa tctcagagat agcaaatgcc acctgaccag aagtctttgt tatatggatg   4140

ggaaccctaa cttagggctt gggcagggga aagagaaaga agatgagaga ttatacttca   4200

tgagtcttag caatatggga gcaggttttc actgaattct gagggtgcct ctgcatgtcc   4260

tccaaggcaa agtttggcaa actgtggccc ccccactgtc atattttgtt aataaaattt   4320

tattggaaca caatcaca                                                 4338


<210>  6721
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6721

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6722
<211>  4098
<212>  DNA
<213>  Homo sapiens

<400>  6722
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gagccaaaag aagacccaga gagtgtcact cctctttgaa   1800

gacgatgttg atagcggagg ctctctgttt ggctctcctc ccacatctgt tcctcctgca   1860

acaaaggaag gacttttgac tagatctgct caggaaacag tcaagcattc tgatttattt   1920

tcttcatcat ccccatggga caaaggaacc aagcctagaa ccaaaactgt tcttagcttg   1980

tttgatgagg aagaggataa aatggaagat caaaacatta tccaggctcc acagaaagaa   2040

gtaggaaagg gctgcgatcc tgatgcccac cccaagagca caggtgtctt ccaggatgaa   2100

gagctgcttt tcagccacaa gctccaaaag gacaatgacc cagatgttga cctttttgct   2160

ggcaccaaaa aaaccaagct gttagagcca agtgttggga gcctgtttgg ggatgatgaa   2220

gatgatgatc ttttcagctc tgccaagtcc cagcctttgg tacaagagaa aaagagagta   2280

gtgaaaaaag accactctgt taactctttc aaaaaccaga aacatcctga atccattcaa   2340

ggtagtaaag aaaaaggcat atggaagccg gaaacacctc aggcaaattt agcgatcaac   2400

ccagcggcct tgctgcccac agcggcttcc cagatctctg aagtaaagcc tgttttgcca   2460

gaattggctt ttccttcatc tgaacacaga aggagccacg gtctggaaag tgtgcctgtc   2520

cttcccggga gtggggaggc cggtgtgagt tttgatcttc cagctcaggc agacacctta   2580

cacagtgcaa acaagagccg tgtcaagatg agagggaagc gtagaccgca gacccgtgca   2640

gctaggcggc tggctgctca ggagtccagc gaggctgagg acatgagcgt ccccagagga   2700

cccattgcac agtgggctga tggcgccatt tccccaaatg gccatcggcc acagctcaga   2760

gcagccagtg gagaagacag cactgaggag gccctggcag ctgccgctgc accttgggaa   2820

ggtggtcctg tgcctggagt ggacacaagc ccctttgcaa agtctctggg tcattccaga   2880

ggggaggctg acctttttga ttctggggac attttttcca cgggcactgg atctcagtcc   2940

gtggagagaa caaaacccaa ggcaaagata gcagagaatc ctgccaaccc accagtgggt   3000

ggtaaagcaa agagccccat gtttcctgct ctaggcgagg ccagcagtga tgatgatctc   3060

tttcagtctg ctaaaccaaa accagcaaag aaaacaaatc cctttcctct cctggaagat   3120

gaggatgacc tctttacaga tcagaaagtc aagaagaatg agacaaaatc cagtagtcag   3180

caggatgtca tattaacaac acaagatatt tttgaggatg atatatttgc tacggaagca   3240

attaaaccct ctcagaaaac cagagagaag gagaaaacat tggaatctaa tttatttgat   3300

gataacattg atatctttgc tgacttaact gtaaaaccaa aagaaaagtc caaaaagaaa   3360

gtggaagcca agtctatatt tgatgatgat atggatgaca tcttctccac tggtatccag   3420

gctaagacaa ccaaaccaaa aagccgatct gcacaggccg cacctgaacc aagatttgaa   3480

cacaaggtgt ccaacatctt tgatgatccc ctgaatgcct ttggaggcca gtagagcaca   3540

cagggtatcc acatgttacc ctgcagctac attgttgagt tagtgatgat attgtatatg   3600

ctcatggtct taactggatt acaaaaagca aatactagaa cagctagctc atcttttacc   3660

caatgtactt agtatttttc tgcactggtt taatcatgct taatactaca aaacaaaaat   3720

aaatatttca cagtggttgg tttgttttgt ttttaaacca cagtttgatt tagttagcct   3780

tgctggggcc ataatatgct tcagggtgtg taaaagaaga aatctctttg tggctttcat   3840

gggcagggaa tctcagagat agcaaatgcc acctgaccag aagtctttgt tatatggatg   3900

ggaaccctaa cttagggctt gggcagggga aagagaaaga agatgagaga ttatacttca   3960

tgagtcttag caatatggga gcaggttttc actgaattct gagggtgcct ctgcatgtcc   4020

tccaaggcaa agtttggcaa actgtggccc ccccactgtc atattttgtt aataaaattt   4080

tattggaaca caatcaca                                                 4098


<210>  6723
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6723

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6724
<211>  4401
<212>  DNA
<213>  Homo sapiens

<400>  6724
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggatttgttt tcttctcaaa gtgcgagtaa cttaaaaggt gcatctctgc   1380

tgcctggcaa gctccccacg tcggtttccc tgtttgatga tgaagatgaa gaggataatc   1440

tttttggggg tacagctgct aagaagcaga cattgtctct acaagctcag agagaagaga   1500

aagcaaaagc ctccgagctc tccaaaaaga aagcatctgc cctgttgttc agcagtgatg   1560

aggaggacca gtggaatatt cctgcttcac agacccactt agcatctgac agcaggtcta   1620

aaggagaacc cagggattct gggaccctcc agagccagga ggccaaggct gtgaaaaaga   1680

ccagtctctt tgaggaagac aaagaagatg atctttttgc cattgccaag gacagataca   1740

tcctacctcc tattgttccc gaagttgtct gtcaagtttt gtgtatggaa agtaattcat   1800

accttcatca gatctcaaaa gaagctttac acacacaaga agaagttgag ccaaaagaag   1860

acccagagag tgtcactcct ctttgaagac gatgttgata gcggaggctc tctgtttggc   1920

tctcctccca catctgttcc tcctgcaaca aagaaaaaag agactgtctc tgaggcacca   1980

cctttgctgt tcagcgatga agaagagaag gaggcacaac ttggagtgaa gtctgtggat   2040

aagaaggttg agagtgccaa ggagtcatta aaatttggga gaactgatgt ggctgagtca   2100

gaaaaggaag gacttttgac tagatctgct caggaaacag tcaagcattc tgatttattt   2160

tcttcatcat ccccatggga caaaggaacc aagcctagaa ccaaaactgt tcttagcttg   2220

tttgatgagg aagaggataa aatggaagat caaaacatta tccaggctcc acagaaagaa   2280

gtaggaaagg gctgcgatcc tgatgcccac cccaagagca caggtgtctt ccaggatgaa   2340

gagctgcttt tcagccacaa gctccaaaag gacaatgacc cagatgttga cctttttgct   2400

ggcaccaaaa aaaccaagct gttagagcca agtgttggga gcctgtttgg ggatgatgaa   2460

gatgatgatc ttttcagctc tgccaagtcc cagcctttgg tacaagagaa aaagagagta   2520

gtgaaaaaag accactctgt taactctttc aaaaaccaga aacatcctga atccattcaa   2580

ggtagtaaag aaaaaggcat atggaagccg gaaacacctc aggactcatc aggtctcgct   2640

ccatttaaaa ccaaagaacc atccactcgg atcgggaaga tacaagcaaa tttagcgatc   2700

aacccagcgg ccttgctgcc cacagcggct tcccagatct ctgaagtaaa gcctgttttg   2760

ccagaattgg cttttccttc atctgaacac agaaggagcc acggtctgga aagtgtgcct   2820

gtccttcccg ggagtgggga ggccggtgtg agttttgatc ttccagctca ggcagacacc   2880

ttacacagtg caaacaagag ccgtgtcaag atgagaggga agcgtagacc gcagacccgt   2940

gcagctaggc ggctggctgc tcaggagtcc agcgaggctg aggacatgag cgtccccaga   3000

ggacccattg cacagtgggc tgatggcgcc atttccccaa atggccatcg gccacagctc   3060

agagcagcca gtggagaaga cagcactgag gaggccctgg cagctgccgc tgcaccttgg   3120

gaaggtggtc ctgtgcctgg agtggacaca agcccctttg caaagtctct gggtcattcc   3180

agaggggagg ctgacctttt tgattctggg gacatttttt ccacgggcac tggatctcag   3240

tccgtggaga gaacaaaacc caaggcaaag atagcagaga atcctgccaa cccaccagtg   3300

ggtggtaaag caaagagccc catgtttcct gctctaggcg aggccagcag tgatgatgat   3360

ctctttcagt ctgctaaacc aaaaccagca aagaaaacaa atccctttcc tctcctggaa   3420

gatgaggatg acctctttac agatcagaaa gtcaagaaga atgagacaaa atccagtagt   3480

cagcaggatg tcatattaac aacacaagat atttttgagg atgatatatt tgctacggaa   3540

gcaattaaac cctctcagaa aaccagagag aaggagaaaa cattggaatc taatttattt   3600

gatgataaca ttgatatctt tgctgactta actgtaaaac caaaagaaaa gtccaaaaag   3660

aaagtggaag ccaagtctat atttgatgat gatatggatg acatcttctc cactggtatc   3720

caggctaaga caaccaaacc aaaaagccga tctgcacagg ccgcacctga accaagattt   3780

gaacacaagg tgtccaacat ctttgatgat cccctgaatg cctttggagg ccagtagagc   3840

acacagggta tccacatgtt accctgcagc tacattgttg agttagtgat gatattgtat   3900

atgctcatgg tcttaactgg attacaaaaa gcaaatacta gaacagctag ctcatctttt   3960

acccaatgta cttagtattt ttctgcactg gtttaatcat gcttaatact acaaaacaaa   4020

aataaatatt tcacagtggt tggtttgttt tgtttttaaa ccacagtttg atttagttag   4080

ccttgctggg gccataatat gcttcagggt gtgtaaaaga agaaatctct ttgtggcttt   4140

catgggcagg gaatctcaga gatagcaaat gccacctgac cagaagtctt tgttatatgg   4200

atgggaaccc taacttaggg cttgggcagg ggaaagagaa agaagatgag agattatact   4260

tcatgagtct tagcaatatg ggagcaggtt ttcactgaat tctgagggtg cctctgcatg   4320

tcctccaagg caaagtttgg caaactgtgg cccccccact gtcatatttt gttaataaaa   4380

ttttattgga acacaatcac a                                             4401


<210>  6725
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6725

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6726
<211>  4512
<212>  DNA
<213>  Homo sapiens

<400>  6726
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggatttgtt ttcttctcaa agtgcgagta acttaaaagg tgcatctctg ctgcctggca   1500

agctccccac gtcggtttcc ctgtttgatg atgaagatga agaggataat ctttttgggg   1560

gtacagctgc taagaagcag acattgtctc tacaagctca gagagaagag aaagcaaaag   1620

cctccgagct ctccaaaaag aaagcatctg ccctgttgtt cagcagtgat gaggaggacc   1680

agtggaatat tcctgcttca cagacccact tagcatctga cagcaggtct aaaggagaac   1740

ccagggattc tgggaccctc cagagccagg aggccaaggc tgtgaaaaag accagtctct   1800

ttgaggaaga caaagaagat gatctttttg ccattgccaa ggacagatac atcctacctc   1860

ctattgttcc cgaagttgtc tgtcaagttt tgtgtatgga aagtaattca taccttcatc   1920

agatctcaaa agaagcttta cacacacaag aagaagttga gccaaaagaa gacccagaga   1980

gtgtcactcc tctttgaaga cgatgttgat agcggaggct ctctgtttgg ctctcctccc   2040

acatctgttc ctcctgcaac aaagaaaaaa gagactgtct ctgaggcacc acctttgctg   2100

ttcagcgatg aagaagagaa ggaggcacaa cttggagtga agtctgtgga taagaaggtt   2160

gagagtgcca aggagtcatt aaaatttggg agaactgatg tggctgagtc agaaaaggaa   2220

ggacttttga ctagatctgc tcaggaaaca gtcaagcatt ctgatttatt ttcttcatca   2280

tccccatggg acaaaggaac caagcctaga accaaaactg ttcttagctt gtttgatgag   2340

gaagaggata aaatggaaga tcaaaacatt atccaggctc cacagaaaga agtaggaaag   2400

ggctgcgatc ctgatgccca ccccaagagc acaggtgtct tccaggatga agagctgctt   2460

ttcagccaca agctccaaaa ggacaatgac ccagatgttg acctttttgc tggcaccaaa   2520

aaaaccaagc tgttagagcc aagtgttggg agcctgtttg gggatgatga agatgatgat   2580

cttttcagct ctgccaagtc ccagcctttg gtacaagaga aaaagagagt agtgaaaaaa   2640

gaccactctg ttaactcttt caaaaaccag aaacatcctg aatccattca aggtagtaaa   2700

gaaaaaggca tatggaagcc ggaaacacct caggactcat caggtctcgc tccatttaaa   2760

accaaagaac catccactcg gatcgggaag atacaagcaa atttagcgat caacccagcg   2820

gccttgctgc ccacagcggc ttcccagatc tctgaagtaa agcctgtttt gccagaattg   2880

gcttttcctt catctgaaca cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc   2940

gggagtgggg aggccggtgt gagttttgat cttccagctc aggcagacac cttacacagt   3000

gcaaacaaga gccgtgtcaa gatgagaggg aagcgtagac cgcagacccg tgcagctagg   3060

cggctggctg ctcaggagtc cagcgaggct gaggacatga gcgtccccag aggacccatt   3120

gcacagtggg ctgatggcgc catttcccca aatggccatc ggccacagct cagagcagcc   3180

agtggagaag acagcactga ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt   3240

cctgtgcctg gagtggacac aagccccttt gcaaagtctc tgggtcattc cagaggggag   3300

gctgaccttt ttgattctgg ggacattttt tccacgggca ctggatctca gtccgtggag   3360

agaacaaaac ccaaggcaaa gatagcagag aatcctgcca acccaccagt gggtggtaaa   3420

gcaaagagcc ccatgtttcc tgctctaggc gaggccagca gtgatgatga tctctttcag   3480

tctgctaaac caaaaccagc aaagaaaaca aatccctttc ctctcctgga agatgaggat   3540

gacctcttta cagatcagaa agtcaagaag aatgagacaa aatccagtag tcagcaggat   3600

gtcatattaa caacacaaga tatttttgag gatgatatat ttgctacgga agcaattaaa   3660

ccctctcaga aaaccagaga gaaggagaaa acattggaat ctaatttatt tgatgataac   3720

attgatatct ttgctgactt aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa   3780

gccaagtcta tatttgatga tgatatggat gacatcttct ccactggtat ccaggctaag   3840

acaaccaaac caaaaagccg atctgcacag gccgcacctg aaccaagatt tgaacacaag   3900

gtgtccaaca tctttgatga tcccctgaat gcctttggag gccagtagag cacacagggt   3960

atccacatgt taccctgcag ctacattgtt gagttagtga tgatattgta tatgctcatg   4020

gtcttaactg gattacaaaa agcaaatact agaacagcta gctcatcttt tacccaatgt   4080

acttagtatt tttctgcact ggtttaatca tgcttaatac tacaaaacaa aaataaatat   4140

ttcacagtgg ttggtttgtt ttgtttttaa accacagttt gatttagtta gccttgctgg   4200

ggccataata tgcttcaggg tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag   4260

ggaatctcag agatagcaaa tgccacctga ccagaagtct ttgttatatg gatgggaacc   4320

ctaacttagg gcttgggcag gggaaagaga aagaagatga gagattatac ttcatgagtc   4380

ttagcaatat gggagcaggt tttcactgaa ttctgagggt gcctctgcat gtcctccaag   4440

gcaaagtttg gcaaactgtg gcccccccac tgtcatattt tgttaataaa attttattgg   4500

aacacaatca ca                                                       4512


<210>  6727
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6727

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6728
<211>  4484
<212>  DNA
<213>  Homo sapiens

<400>  6728
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagcaca ccacacaaat gagtgatgag gaagaggatg    660

atgatggctg tgaccttttt gctgactctg agaaggagga ggaagatatt gaggacattg    720

aagaaaatac tagacctaaa agaagcagac ctacatcgtt tgcagatgag ctggctgccc    780

gcatcaaggg ggatgccatg ggtcgagtgg acgaggagcc gacaacctta ccctcaggag    840

aagcaaaacc tcggaagaca ctcaaagaga agaaggaaag gagaactcct tcagacgatg    900

aagaggataa cttattcgca ccccccaagc tgaccgacga ggacttctcg ccatttggct    960

ctggaggtgg cctgttcagt ggcggcaagg ggctatttga tgatgaggac gaggagagtg   1020

acctcttcac ggaagcctcc caggatcggc aagctggagc ctctgttaag gaggagtctt   1080

catcatccaa acctggaaag aaaatcccag caggagctgt ttctgtattt ttaggagaca   1140

cggatgtgtt tggtgctgcc tccgttccat cactgaagga gccacagaag cctgagcagc   1200

ccactccaag gaaaagcccc tatggtcccc ctcccactgg cctctttgat gatgatgatg   1260

gtgatgatga tgacgacttt ttctcggcac cccacagcaa accttctaaa acacgcaaag   1320

tccaatccac tgccgatatc tttggtgacg aagaaggaga tctgttcaaa gaaaaagccg   1380

tagcatcgcc agaagccact gtgagtcaga cagatgaaaa taaagcaaga gcagaaaaaa   1440

aggttacctt atcttacagc aaaaatctca agccctcatc agaaacaaag actcaaaaag   1500

gcttattttc agatgaggag gactctgagg atttgttttc ttctcaaagt gcgagtaact   1560

taaaaggtgc atctctgctg cctggcaagc tccccacgtc ggtttccctg tttgatgatg   1620

aagatgaaga ggataatctt tttgggggta cagctgctaa gaagcagaca ttgtctctac   1680

aagctcagag agaagagaaa gcaaaagcct ccgagctctc caaaaagaaa gcatctgccc   1740

tgttgttcag cagtgatgag gaggaccagt ggaatattcc tgcttcacag acccacttag   1800

catctgacag caggtctaaa ggagaaccca gggattctgg gaccctccag agccaggagg   1860

ccaaggctgt gaaaaagacc agtctctttg aggaagacaa agaagatgat ctttttgcca   1920

ttgccaagga cagccaaaag aagacccaga gagtgtcact cctctttgaa gacgatgttg   1980

atagcggagg ctctctgttt ggctctcctc ccacatctgt tcctcctgca acaaagaaaa   2040

aagagactgt ctctgaggca ccacctttgc tgttcagcga tgaagaagag aaggaggcac   2100

aacttggagt gaagtctgtg gataagaagg ttgagagtgc caaggagtca ttaaaatttg   2160

ggagaactga tgtggctgag tcagaaaagg aaggactttt gactagatct gctcaggaaa   2220

cagtcaagca ttctgattta ttttcttcat catccccatg ggacaaagga accaagccta   2280

gaaccaaaac tgttcttagc ttgtttgatg aggaagagga taaaatggaa gatcaaaaca   2340

ttatccaggc tccacagaaa gaagtaggaa agggctgcga tcctgatgcc caccccaaga   2400

gcacaggtgt cttccaggat gaagagctgc ttttcagcca caagctccaa aaggacaatg   2460

acccagatgt tgaccttttt gctggcacca aaaaaaccaa gctgttagag ccaagtgttg   2520

ggagcctgtt tggggatgat gaagatgatg atcttttcag ctctgccaag tcccagcctt   2580

tggtacaaga gaaaaagaga gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc   2640

agaaacatcc tgaatccatt caaggtagta aagaaaaagg catatggaag ccggaaacac   2700

ctcaggactc atcaggtctc gctccattta aaaccaaaga accatccact cggatcggga   2760

agatacaagc aaatttagcg atcaacccag cggccttgct gcccacagcg gcttcccaga   2820

tctctgaagt aaagcctgtt ttgccagaat tggcttttcc ttcatctgaa cacagaagga   2880

gccacggtct ggaaagtgtg cctgtccttc ccgggagtgg ggaggccggt gtgagttttg   2940

atcttccagc tcaggcagac accttacaca gtgcaaacaa gagccgtgtc aagatgagag   3000

ggaagcgtag accgcagacc cgtgcagcta ggcggctggc tgctcaggag tccagcgagg   3060

ctgaggacat gagcgtcccc agaggaccca ttgcacagtg ggctgatggc gccatttccc   3120

caaatggcca tcggccacag ctcagagcag ccagtggaga agacagcact gaggaggccc   3180

tggcagctgc cgctgcacct tgggaaggtg gtcctgtgcc tggagtggac acaagcccct   3240

ttgcaaagtc tctgggtcat tccagagggg aggctgacct ttttgattct ggggacattt   3300

tttccacggg cactggatct cagtccgtgg agagaacaaa acccaaggca aagatagcag   3360

agaatcctgc caacccacca gtgggtggta aagcaaagag ccccatgttt cctgctctag   3420

gcgaggccag cagtgatgat gatctctttc agtctgctaa accaaaacca gcaaagaaaa   3480

caaatccctt tcctctcctg gaagatgagg atgacctctt tacagatcag aaagtcaaga   3540

agaatgagac aaaatccagt agtcagcagg atgtcatatt aacaacacaa gatatttttg   3600

aggatgatat atttgctacg gaagcaatta aaccctctca gaaaaccaga gagaaggaga   3660

aaacattgga atctaattta tttgatgata acattgatat ctttgctgac ttaactgtaa   3720

aaccaaaaga aaagtccaaa aagaaagtgg aagccaagtc tatatttgat gatgatatgg   3780

atgacatctt ctccactggt atccaggcta agacaaccaa accaaaaagc cgatctgcac   3840

aggccgcacc tgaaccaaga tttgaacaca aggtgtccaa catctttgat gatcccctga   3900

atgcctttgg aggccagtag agcacacagg gtatccacat gttaccctgc agctacattg   3960

ttgagttagt gatgatattg tatatgctca tggtcttaac tggattacaa aaagcaaata   4020

ctagaacagc tagctcatct tttacccaat gtacttagta tttttctgca ctggtttaat   4080

catgcttaat actacaaaac aaaaataaat atttcacagt ggttggtttg ttttgttttt   4140

aaaccacagt ttgatttagt tagccttgct ggggccataa tatgcttcag ggtgtgtaaa   4200

agaagaaatc tctttgtggc tttcatgggc agggaatctc agagatagca aatgccacct   4260

gaccagaagt ctttgttata tggatgggaa ccctaactta gggcttgggc aggggaaaga   4320

gaaagaagat gagagattat acttcatgag tcttagcaat atgggagcag gttttcactg   4380

aattctgagg gtgcctctgc atgtcctcca aggcaaagtt tggcaaactg tggccccccc   4440

actgtcatat tttgttaata aaattttatt ggaacacaat caca                    4484


<210>  6729
<211>  1286
<212>  PRT
<213>  Homo sapiens

<400>  6729

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln His Thr Thr 
            180                 185                 190


Gln Met Ser Asp Glu Glu Glu Asp Asp Asp Gly Cys Asp Leu Phe Ala 
        195                 200                 205


Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu Asp Ile Glu Glu Asn Thr 
    210                 215                 220


Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala 
225                 230                 235                 240


Arg Ile Lys Gly Asp Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr 
                245                 250                 255


Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys 
            260                 265                 270


Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro 
        275                 280                 285


Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly 
    290                 295                 300


Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser 
305                 310                 315                 320


Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val 
                325                 330                 335


Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly 
            340                 345                 350


Ala Val Ser Val Phe Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser 
        355                 360                 365


Val Pro Ser Leu Lys Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg 
    370                 375                 380


Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp 
385                 390                 395                 400


Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser 
                405                 410                 415


Lys Thr Arg Lys Val Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu 
            420                 425                 430


Gly Asp Leu Phe Lys Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val 
        435                 440                 445


Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu 
    450                 455                 460


Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys 
465                 470                 475                 480


Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln 
                485                 490                 495


Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro 
            500                 505                 510


Thr Ser Val Ser Leu Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe 
        515                 520                 525


Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg 
    530                 535                 540


Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala 
545                 550                 555                 560


Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser 
                565                 570                 575


Gln Thr His Leu Ala Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp 
            580                 585                 590


Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser 
        595                 600                 605


Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp 
    610                 615                 620


Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val 
625                 630                 635                 640


Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro 
                645                 650                 655


Ala Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe 
            660                 665                 670


Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp 
        675                 680                 685


Lys Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp 
    690                 695                 700


Val Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu 
705                 710                 715                 720


Thr Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys 
                725                 730                 735


Gly Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu 
            740                 745                 750


Glu Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu 
        755                 760                 765


Val Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val 
    770                 775                 780


Phe Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn 
785                 790                 795                 800


Asp Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu 
                805                 810                 815


Glu Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu 
            820                 825                 830


Phe Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val 
        835                 840                 845


Val Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro 
    850                 855                 860


Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr 
865                 870                 875                 880


Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser 
                885                 890                 895


Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala 
            900                 905                 910


Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu 
        915                 920                 925


Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu 
    930                 935                 940


Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe 
945                 950                 955                 960


Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg 
                965                 970                 975


Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg 
            980                 985                 990


Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg 
        995                 1000                1005


Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His 
    1010                1015                1020


Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala 
1025                1030                1035                1040


Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val 
                1045                1050                1055


Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala 
            1060                1065                1070


Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln 
        1075                1080                1085


Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala 
    1090                1095                1100


Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu 
1105                1110                1115                1120


Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys 
                1125                1130                1135


Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp 
            1140                1145                1150


Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser 
        1155                1160                1165


Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile 
    1170                1175                1180


Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu 
1185                1190                1195                1200


Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala 
                1205                1210                1215


Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala 
            1220                1225                1230


Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile 
        1235                1240                1245


Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro 
    1250                1255                1260


Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu 
1265                1270                1275                1280


Asn Ala Phe Gly Gly Gln 
                1285


<210>  6730
<211>  4310
<212>  DNA
<213>  Homo sapiens

<400>  6730
gctctgcggt cctcggcctg tgctggcagc ctcggagccc accgagccgg gcggctggga     60

tgatgaaccg gacgaccccc gaccaggagc tggtgccggc gtcggagccc gtgtgggagc    120

ggccgtggtc ggtggaggag atccgcagga gcagccagag ctggtcgctg gcggccgacg    180

cgggccgtgt atatgatgaa gaagtggagg agccagtact caaggctgag gcagaaaaaa    240

cagagcagga gaagacacga gagcagaaag aagtagatct cattcctaaa gtccaggagg    300

ctgtgaacta tggcttacaa gtattggaca gtgcctttga gcaacttgat atcaaagcag    360

gaaactcaga ctccgaggaa gatgatgcta atgggcgggt ggaactgatc cttgaaccaa    420

aggatctata cattgatcgt cctttaccat atctcattgg gtcaaagctg ttcatggaac    480

aagaagatgt aggtcttgga gagctgtcca gtgaagaagg ctctgtaggc agtgatcgtg    540

gcagtattgt ggacactgag gaagagaaag aagaggagga gtcagatgaa gattttgccc    600

atcacagtga caatgaacaa aaccagaaaa gaagcagacc tacatcgttt gcagatgagc    660

tggctgcccg catcaagggg gatgccatgg gtcgagtgga cgaggagccg acaaccttac    720

cctcaggaga agcaaaacct cggaagacac tcaaagagaa gaaggaaagg agaactcctt    780

cagacgatga agaggataac ttattcgcac cccccaagct gaccgacgag gacttctcgc    840

catttggctc tggaggtggc ctgttcagtg gcggcaaggg gctatttgat gatgaggacg    900

aggagagtga cctcttcacg gaagcctccc aggatcggca agctggagcc tctgttaagg    960

aggagtcttc atcatccaaa cctggaaaga aaatcccagc aggagctgtt tctgtatttt   1020

taggagacac ggatgtgttt ggtgctgcct ccgttccatc actgaaggag ccacagaagc   1080

ctgagcagcc cactccaagg aaaagcccct atggtccccc tcccactggc ctctttgatg   1140

atgatgatgg tgatgatgat gacgactttt tctcggcacc ccacagcaaa ccttctaaaa   1200

cacgcaaagt ccaatccact gccgatatct ttggtgacga agaaggagat ctgttcaaag   1260

aaaaagccgt agcatcgcca gaagccactg tgagtcagac agatgaaaat aaagcaagag   1320

cagaaaaaaa ggttacctta tcttacagca aaaatctcaa gccctcatca gaaacaaaga   1380

ctcaaaaagg cttattttca gatgaggagg actctgagga tttgttttct tctcaaagtg   1440

cgagtaactt aaaaggtgca tctctgctgc ctggcaagct ccccacgtcg gtttccctgt   1500

ttgatgatga agatgaagag gataatcttt ttgggggtac agctgctaag aagcagacat   1560

tgtctctaca agctcagaga gaagagaaag caaaagcctc cgagctctcc aaaaagaaag   1620

catctgccct gttgttcagc agtgatgagg aggaccagtg gaatattcct gcttcacaga   1680

cccacttagc atctgacagc aggtctaaag gagaacccag ggattctggg accctccaga   1740

gccaggaggc caaggctgtg aaaaagacca gtctctttga ggaagacaaa gaagatgatc   1800

tttttgccat tgccaaggac agccaaaaga agacccagag agtgtcactc ctctttgaag   1860

acgatgttga tagcggaggc tctctgtttg gctctcctcc cacatctgtt cctcctgcaa   1920

caaagaaaaa agagactgtc tctgaggcac cacctttgct gttcagcgat gaagaagaga   1980

aggaggcaca acttggagtg aagtctgtgg ataagaaggt tgagagtgcc aaggagtcat   2040

taaaatttgg gagaactgat gtggctgagt cagaaaagga aggacttttg actagatctg   2100

ctcaggaaac agtcaagcat tctgatttat tttcttcatc atccccatgg gacaaaggaa   2160

ccaagcctag aaccaaaact gttcttagct tgtttgatga ggaagaggat aaaatggaag   2220

atcaaaacat tatccaggct ccacagaaag aagtaggaaa gggctgcgat cctgatgccc   2280

accccaagag cacaggtgtc ttccaggatg aagagctgct tttcagccac aagctccaaa   2340

aggacaatga cccagatgtt gacctttttg ctggcaccaa aaaaaccaag ctgttagagc   2400

caagtgttgg gagcctgttt ggggatgatg aagatgatga tcttttcagc tctgccaagt   2460

cccagccttt ggtacaagag aaaaagagag tagtgaaaaa agaccactct gttaactctt   2520

tcaaaaacca gaaacatcct gaatccattc aaggtagtaa agaaaaaggc atatggaagc   2580

cggaaacacc tcaggcaaat ttagcgatca acccagcggc cttgctgccc acagcggctt   2640

cccagatctc tgaagtaaag cctgttttgc cagaattggc ttttccttca tctgaacaca   2700

gaaggagcca cggtctggaa agtgtgcctg tccttcccgg gagtggggag gccggtgtga   2760

gttttgatct tccagctcag gcagacacct tacacagtgc aaacaagagc cgtgtcaaga   2820

tgagagggaa gcgtagaccg cagacccgtg cagctaggcg gctggctgct caggagtcca   2880

gcgaggctga ggacatgagc gtccccagag gacccattgc acagtgggct gatggcgcca   2940

tttccccaaa tggccatcgg ccacagctca gagcagccag tggagaagac agcactgagg   3000

aggccctggc agctgccgct gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa   3060

gcccctttgc aaagtctctg ggtcattcca gaggggaggc tgaccttttt gattctgggg   3120

acattttttc cacgggcact ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga   3180

tagcagagaa tcctgccaac ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg   3240

ctctaggcga ggccagcagt gatgatgatc tctttcagtc tgctaaacca aaaccagcaa   3300

agaaaacaaa tccctttcct ctcctggaag atgaggatga cctctttaca gatcagaaag   3360

tcaagaagaa tgagacaaaa tccagtagtc agcaggatgt catattaaca acacaagata   3420

tttttgagga tgatatattt gctacggaag caattaaacc ctctcagaaa accagagaga   3480

aggagaaaac attggaatct aatttatttg atgataacat tgatatcttt gctgacttaa   3540

ctgtaaaacc aaaagaaaag tccaaaaaga aagtggaagc caagtctata tttgatgatg   3600

atatggatga catcttctcc actggtatcc aggctaagac aaccaaacca aaaagccgat   3660

ctgcacaggc cgcacctgaa ccaagatttg aacacaaggt gtccaacatc tttgatgatc   3720

ccctgaatgc ctttggaggc cagtagagca cacagggtat ccacatgtta ccctgcagct   3780

acattgttga gttagtgatg atattgtata tgctcatggt cttaactgga ttacaaaaag   3840

caaatactag aacagctagc tcatctttta cccaatgtac ttagtatttt tctgcactgg   3900

tttaatcatg cttaatacta caaaacaaaa ataaatattt cacagtggtt ggtttgtttt   3960

gtttttaaac cacagtttga tttagttagc cttgctgggg ccataatatg cttcagggtg   4020

tgtaaaagaa gaaatctctt tgtggctttc atgggcaggg aatctcagag atagcaaatg   4080

ccacctgacc agaagtcttt gttatatgga tgggaaccct aacttagggc ttgggcaggg   4140

gaaagagaaa gaagatgaga gattatactt catgagtctt agcaatatgg gagcaggttt   4200

tcactgaatt ctgagggtgc ctctgcatgt cctccaaggc aaagtttggc aaactgtggc   4260

ccccccactg tcatattttg ttaataaaat tttattggaa cacaatcaca              4310


<210>  6731
<211>  1228
<212>  PRT
<213>  Homo sapiens

<400>  6731

Met Met Asn Arg Thr Thr Pro Asp Gln Glu Leu Val Pro Ala Ser Glu 
1               5                   10                  15


Pro Val Trp Glu Arg Pro Trp Ser Val Glu Glu Ile Arg Arg Ser Ser 
            20                  25                  30


Gln Ser Trp Ser Leu Ala Ala Asp Ala Gly Arg Val Tyr Asp Glu Glu 
        35                  40                  45


Val Glu Glu Pro Val Leu Lys Ala Glu Ala Glu Lys Thr Glu Gln Glu 
    50                  55                  60


Lys Thr Arg Glu Gln Lys Glu Val Asp Leu Ile Pro Lys Val Gln Glu 
65                  70                  75                  80


Ala Val Asn Tyr Gly Leu Gln Val Leu Asp Ser Ala Phe Glu Gln Leu 
                85                  90                  95


Asp Ile Lys Ala Gly Asn Ser Asp Ser Glu Glu Asp Asp Ala Asn Gly 
            100                 105                 110


Arg Val Glu Leu Ile Leu Glu Pro Lys Asp Leu Tyr Ile Asp Arg Pro 
        115                 120                 125


Leu Pro Tyr Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val 
    130                 135                 140


Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg 
145                 150                 155                 160


Gly Ser Ile Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Glu Ser Asp 
                165                 170                 175


Glu Asp Phe Ala His His Ser Asp Asn Glu Gln Asn Gln Lys Arg Ser 
            180                 185                 190


Arg Pro Thr Ser Phe Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp 
        195                 200                 205


Ala Met Gly Arg Val Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu 
    210                 215                 220


Ala Lys Pro Arg Lys Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro 
225                 230                 235                 240


Ser Asp Asp Glu Glu Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp 
                245                 250                 255


Glu Asp Phe Ser Pro Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly 
            260                 265                 270


Lys Gly Leu Phe Asp Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu 
        275                 280                 285


Ala Ser Gln Asp Arg Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser 
    290                 295                 300


Ser Ser Lys Pro Gly Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe 
305                 310                 315                 320


Leu Gly Asp Thr Asp Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys 
                325                 330                 335


Glu Pro Gln Lys Pro Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly 
            340                 345                 350


Pro Pro Pro Thr Gly Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp 
        355                 360                 365


Asp Phe Phe Ser Ala Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val 
    370                 375                 380


Gln Ser Thr Ala Asp Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys 
385                 390                 395                 400


Glu Lys Ala Val Ala Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu 
                405                 410                 415


Asn Lys Ala Arg Ala Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn 
            420                 425                 430


Leu Lys Pro Ser Ser Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp 
        435                 440                 445


Glu Glu Asp Ser Glu Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu 
    450                 455                 460


Lys Gly Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu 
465                 470                 475                 480


Phe Asp Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala 
                485                 490                 495


Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys 
            500                 505                 510


Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser 
        515                 520                 525


Asp Glu Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala 
    530                 535                 540


Ser Asp Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln 
545                 550                 555                 560


Ser Gln Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp 
                565                 570                 575


Lys Glu Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr 
            580                 585                 590


Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser 
        595                 600                 605


Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys 
    610                 615                 620


Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu 
625                 630                 635                 640


Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser 
                645                 650                 655


Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu 
            660                 665                 670


Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser 
        675                 680                 685


Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg 
    690                 695                 700


Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu 
705                 710                 715                 720


Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys 
                725                 730                 735


Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu 
            740                 745                 750


Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp 
        755                 760                 765


Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly 
    770                 775                 780


Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys 
785                 790                 795                 800


Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His 
                805                 810                 815


Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly 
            820                 825                 830


Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu 
        835                 840                 845


Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser 
    850                 855                 860


Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His 
865                 870                 875                 880


Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly 
                885                 890                 895


Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His 
            900                 905                 910


Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln 
        915                 920                 925


Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu 
    930                 935                 940


Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala 
945                 950                 955                 960


Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu 
                965                 970                 975


Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly 
            980                 985                 990


Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly 
        995                 1000                1005


His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser 
    1010                1015                1020


Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys 
1025                1030                1035                1040


Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser 
                1045                1050                1055


Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe 
            1060                1065                1070


Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu 
        1075                1080                1085


Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn 
    1090                1095                1100


Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp 
1105                1110                1115                1120


Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln 
                1125                1130                1135


Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp 
            1140                1145                1150


Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser 
        1155                1160                1165


Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp 
    1170                1175                1180


Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg 
1185                1190                1195                1200


Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn 
                1205                1210                1215


Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            1220                1225


<210>  6732
<211>  285
<212>  DNA
<213>  Homo sapiens

<400>  6732
atgcctcaca ggggacaggg cagcatttcc ttcagcagtg gagcctattc ctttcatcat     60

gtacaggatc tatacattga tcgtccttta ccatatctca ttgggtcaaa gctgttcatg    120

gaacaagaag atgtaggtct tggagagctg tccagtgaag aaggctctgt aggcagtgat    180

cgtggcagta ttgtggacac tgaggaagag aaagaagagg aggtaagggc tgtttggtat    240

gaccaggtca cggtgggcag caagcttaat ttaagatggg cctag                    285


<210>  6733
<211>  94
<212>  PRT
<213>  Homo sapiens

<400>  6733

Met Pro His Arg Gly Gln Gly Ser Ile Ser Phe Ser Ser Gly Ala Tyr 
1               5                   10                  15


Ser Phe His His Val Gln Asp Leu Tyr Ile Asp Arg Pro Leu Pro Tyr 
            20                  25                  30


Leu Ile Gly Ser Lys Leu Phe Met Glu Gln Glu Asp Val Gly Leu Gly 
        35                  40                  45


Glu Leu Ser Ser Glu Glu Gly Ser Val Gly Ser Asp Arg Gly Ser Ile 
    50                  55                  60


Val Asp Thr Glu Glu Glu Lys Glu Glu Glu Val Arg Ala Val Trp Tyr 
65                  70                  75                  80


Asp Gln Val Thr Val Gly Ser Lys Leu Asn Leu Arg Trp Ala 
                85                  90


<210>  6734
<211>  4095
<212>  DNA
<213>  Homo sapiens

<400>  6734
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggattt gttttcttct caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg   1080

gcaagctccc cacgtcggtt tccctgtttg atgatgaaga tgaagaggat aatctttttg   1140

ggggtacagc tgctaagaag cagacattgt ctctacaagc tcagagagaa gagaaagcaa   1200

aagcctccga gctctccaaa aagaaagcat ctgccctgtt gttcagcagt gatgaggagg   1260

accagtggaa tattcctgct tcacagaccc acttagcatc tgacagcagg tctaaaggag   1320

aacccaggga ttctgggacc ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc   1380

tctttgagga agacaaagaa gatgatcttt ttgccattgc caaggacaga tacatcctac   1440

ctcctattgt tcccgaagtt gtctgtcaag ttttgtgtat ggaaagtaat tcataccttc   1500

atcagatctc aaaagaagct ttacacacac aagaagaagt tgagccaaaa gaagacccag   1560

agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt tggctctcct   1620

cccacatctg ttcctcctgc aacaaagaaa aaagagactg tctctgaggc accacctttg   1680

ctgttcagcg atgaagaaga gaaggaggca caacttggag tgaagtctgt ggataagaag   1740

gttgagagtg ccaaggagtc attaaaattt gggagaactg atgtggctga gtcagaaaag   1800

gaaggacttt tgactagatc tgctcaggaa acagtcaagc attctgattt attttcttca   1860

tcatccccat gggacaaagg aaccaagcct agaaccaaaa ctgttcttag cttgtttgat   1920

gaggaagagg ataaaatgga agatcaaaac attatccagg ctccacagaa agaagtagga   1980

aagggctgcg atcctgatgc ccaccccaag agcacaggtg tcttccagga tgaagagctg   2040

cttttcagcc acaagctcca aaaggacaat gacccagatg ttgacctttt tgctggcacc   2100

aaaaaaacca agctgttaga gccaagtgtt gggagcctgt ttggggatga tgaagatgat   2160

gatcttttca gctctgccaa gtcccagcct ttggtacaag agaaaaagag agtagtgaaa   2220

aaagaccact ctgttaactc tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt   2280

aaagaaaaag gcatatggaa gccggaaaca cctcaggact catcaggtct cgctccattt   2340

aaaaccaaag aaccatccac tcggatcggg aagatacaag caaatttagc gatcaaccca   2400

gcggccttgc tgcccacagc ggcttcccag atctctgaag taaagcctgt tttgccagaa   2460

ttggcttttc cttcatctga acacagaagg agccacggtc tggaaagtgt gcctgtcctt   2520

cccgggagtg gggaggccgg tgtgagtttt gatcttccag ctcaggcaga caccttacac   2580

agtgcaaaca agagccgtgt caagatgaga gggaagcgta gaccgcagac ccgtgcagct   2640

aggcggctgg ctgctcagga gtccagcgag gctgaggaca tgagcgtccc cagaggaccc   2700

attgcacagt gggctgatgg cgccatttcc ccaaatggcc atcggccaca gctcagagca   2760

gccagtggag aagacagcac tgaggaggcc ctggcagctg ccgctgcacc ttgggaaggt   2820

ggtcctgtgc ctggagtgga cacaagcccc tttgcaaagt ctctgggtca ttccagaggg   2880

gaggctgacc tttttgattc tggggacatt ttttccacgg gcactggatc tcagtccgtg   2940

gagagaacaa aacccaaggc aaagatagca gagaatcctg ccaacccacc agtgggtggt   3000

aaagcaaaga gccccatgtt tcctgctcta ggcgaggcca gcagtgatga tgatctcttt   3060

cagtctgcta aaccaaaacc agcaaagaaa acaaatccct ttcctctcct ggaagatgag   3120

gatgacctct ttacagatca gaaagtcaag aagaatgaga caaaatccag tagtcagcag   3180

gatgtcatat taacaacaca agatattttt gaggatgata tatttgctac ggaagcaatt   3240

aaaccctctc agaaaaccag agagaaggag aaaacattgg aatctaattt atttgatgat   3300

aacattgata tctttgctga cttaactgta aaaccaaaag aaaagtccaa aaagaaagtg   3360

gaagccaagt ctatatttga tgatgatatg gatgacatct tctccactgg tatccaggct   3420

aagacaacca aaccaaaaag ccgatctgca caggccgcac ctgaaccaag atttgaacac   3480

aaggtgtcca acatctttga tgatcccctg aatgcctttg gaggccagta gagcacacag   3540

ggtatccaca tgttaccctg cagctacatt gttgagttag tgatgatatt gtatatgctc   3600

atggtcttaa ctggattaca aaaagcaaat actagaacag ctagctcatc ttttacccaa   3660

tgtacttagt atttttctgc actggtttaa tcatgcttaa tactacaaaa caaaaataaa   3720

tatttcacag tggttggttt gttttgtttt taaaccacag tttgatttag ttagccttgc   3780

tggggccata atatgcttca gggtgtgtaa aagaagaaat ctctttgtgg ctttcatggg   3840

cagggaatct cagagatagc aaatgccacc tgaccagaag tctttgttat atggatggga   3900

accctaactt agggcttggg caggggaaag agaaagaaga tgagagatta tacttcatga   3960

gtcttagcaa tatgggagca ggttttcact gaattctgag ggtgcctctg catgtcctcc   4020

aaggcaaagt ttggcaaact gtggcccccc cactgtcata ttttgttaat aaaattttat   4080

tggaacacaa tcaca                                                    4095


<210>  6735
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6735

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6736
<211>  4119
<212>  DNA
<213>  Homo sapiens

<400>  6736
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggaggacc agtggaatat tcctgcttca cagacccact   1380

tagcatctga cagcaggtct aaaggagaac ccagggattc tgggaccctc cagagccagg   1440

aggccaaggc tgtgaaaaag accagtctct ttgaggaaga caaagaagat gatctttttg   1500

ccattgccaa ggacagatac atcctacctc ctattgttcc cgaagttgtc tgtcaagttt   1560

tgtgtatgga aagtaattca taccttcatc agatctcaaa agaagcttta cacacacaag   1620

aagaagttga gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat   1680

agcggaggct ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa   1740

gagactgtct ctgaggcacc acctttgctg ttcagcgatg aagaagagaa ggaggcacaa   1800

cttggagtga agtctgtgga taagaaggtt gagagtgcca aggagtcatt aaaatttggg   1860

agaactgatg tggctgagtc agaaaaggaa ggacttttga ctagatctgc tcaggaaaca   1920

gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac caagcctaga   1980

accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga tcaaaacatt   2040

atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca ccccaagagc   2100

acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa ggacaatgac   2160

ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg   2220

agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc ccagcctttg   2280

gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt caaaaaccag   2340

aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct   2400

caggcaaatt tagcgatcaa cccagcggcc ttgctgccca cagcggcttc ccagatctct   2460

gaagtaaagc ctgttttgcc agaattggct tttccttcat ctgaacacag aaggagccac   2520

ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg ccggtgtgag ttttgatctt   2580

ccagctcagg cagacacctt acacagtgca aacaagagcc gtgtcaagat gagagggaag   2640

cgtagaccgc agacccgtgc agctaggcgg ctggctgctc aggagtccag cgaggctgag   2700

gacatgagcg tccccagagg acccattgca cagtgggctg atggcgccat ttccccaaat   2760

ggccatcggc cacagctcag agcagccagt ggagaagaca gcactgagga ggccctggca   2820

gctgccgctg caccttggga aggtggtcct gtgcctggag tggacacaag cccctttgca   2880

aagtctctgg gtcattccag aggggaggct gacctttttg attctgggga cattttttcc   2940

acgggcactg gatctcagtc cgtggagaga acaaaaccca aggcaaagat agcagagaat   3000

cctgccaacc caccagtggg tggtaaagca aagagcccca tgtttcctgc tctaggcgag   3060

gccagcagtg atgatgatct ctttcagtct gctaaaccaa aaccagcaaa gaaaacaaat   3120

ccctttcctc tcctggaaga tgaggatgac ctctttacag atcagaaagt caagaagaat   3180

gagacaaaat ccagtagtca gcaggatgtc atattaacaa cacaagatat ttttgaggat   3240

gatatatttg ctacggaagc aattaaaccc tctcagaaaa ccagagagaa ggagaaaaca   3300

ttggaatcta atttatttga tgataacatt gatatctttg ctgacttaac tgtaaaacca   3360

aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat ttgatgatga tatggatgac   3420

atcttctcca ctggtatcca ggctaagaca accaaaccaa aaagccgatc tgcacaggcc   3480

gcacctgaac caagatttga acacaaggtg tccaacatct ttgatgatcc cctgaatgcc   3540

tttggaggcc agtagagcac acagggtatc cacatgttac cctgcagcta cattgttgag   3600

ttagtgatga tattgtatat gctcatggtc ttaactggat tacaaaaagc aaatactaga   3660

acagctagct catcttttac ccaatgtact tagtattttt ctgcactggt ttaatcatgc   3720

ttaatactac aaaacaaaaa taaatatttc acagtggttg gtttgttttg tttttaaacc   3780

acagtttgat ttagttagcc ttgctggggc cataatatgc ttcagggtgt gtaaaagaag   3840

aaatctcttt gtggctttca tgggcaggga atctcagaga tagcaaatgc cacctgacca   3900

gaagtctttg ttatatggat gggaacccta acttagggct tgggcagggg aaagagaaag   3960

aagatgagag attatacttc atgagtctta gcaatatggg agcaggtttt cactgaattc   4020

tgagggtgcc tctgcatgtc ctccaaggca aagtttggca aactgtggcc cccccactgt   4080

catattttgt taataaaatt ttattggaac acaatcaca                          4119


<210>  6737
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6737

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6738
<211>  4182
<212>  DNA
<213>  Homo sapiens

<400>  6738
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggaggacc agtggaatat tcctgcttca cagacccact   1380

tagcatctga cagcaggtct aaaggagaac ccagggattc tgggaccctc cagagccagg   1440

aggccaaggc tgtgaaaaag accagtctct ttgaggaaga caaagaagat gatctttttg   1500

ccattgccaa ggacagatac atcctacctc ctattgttcc cgaagttgtc tgtcaagttt   1560

tgtgtatgga aagtaattca taccttcatc agatctcaaa agaagcttta cacacacaag   1620

aagaagttga gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat   1680

agcggaggct ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa   1740

gagactgtct ctgaggcacc acctttgctg ttcagcgatg aagaagagaa ggaggcacaa   1800

cttggagtga agtctgtgga taagaaggtt gagagtgcca aggagtcatt aaaatttggg   1860

agaactgatg tggctgagtc agaaaaggaa ggacttttga ctagatctgc tcaggaaaca   1920

gtcaagcatt ctgatttatt ttcttcatca tccccatggg acaaaggaac caagcctaga   1980

accaaaactg ttcttagctt gtttgatgag gaagaggata aaatggaaga tcaaaacatt   2040

atccaggctc cacagaaaga agtaggaaag ggctgcgatc ctgatgccca ccccaagagc   2100

acaggtgtct tccaggatga agagctgctt ttcagccaca agctccaaaa ggacaatgac   2160

ccagatgttg acctttttgc tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg   2220

agcctgtttg gggatgatga agatgatgat cttttcagct ctgccaagtc ccagcctttg   2280

gtacaagaga aaaagagagt agtgaaaaaa gaccactctg ttaactcttt caaaaaccag   2340

aaacatcctg aatccattca aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct   2400

caggactcat caggtctcgc tccatttaaa accaaagaac catccactcg gatcgggaag   2460

atacaagcaa atttagcgat caacccagcg gccttgctgc ccacagcggc ttcccagatc   2520

tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca cagaaggagc   2580

cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt gagttttgat   2640

cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa gatgagaggg   2700

aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc cagcgaggct   2760

gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc catttcccca   2820

aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga ggaggccctg   2880

gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacac aagccccttt   2940

gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg ggacattttt   3000

tccacgggca ctggatctca gtccgtggag agaacaaaac ccaaggcaaa gatagcagag   3060

aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc tgctctaggc   3120

gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc aaagaaaaca   3180

aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa agtcaagaag   3240

aatgagacaa aatccagtag tcagcaggat gtcatattaa caacacaaga tatttttgag   3300

gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga gaaggagaaa   3360

acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt aactgtaaaa   3420

ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga tgatatggat   3480

gacatcttct ccactggtat ccaggctaag acaaccaaac caaaaagccg atctgcacag   3540

gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga tcccctgaat   3600

gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag ctacattgtt   3660

gagttagtga tgatattgta tatgctcatg gtcttaactg gattacaaaa agcaaatact   3720

agaacagcta gctcatcttt tacccaatgt acttagtatt tttctgcact ggtttaatca   3780

tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt ttgtttttaa   3840

accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg tgtgtaaaag   3900

aagaaatctc tttgtggctt tcatgggcag ggaatctcag agatagcaaa tgccacctga   3960

ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcttgggcag gggaaagaga   4020

aagaagatga gagattatac ttcatgagtc ttagcaatat gggagcaggt tttcactgaa   4080

ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg gcccccccac   4140

tgtcatattt tgttaataaa attttattgg aacacaatca ca                      4182


<210>  6739
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6739

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6740
<211>  4004
<212>  DNA
<213>  Homo sapiens

<400>  6740
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggaggacc agtggaatat tcctgcttca cagacccact   1380

tagcatctga cagcaggtct aaaggagaac ccagggattc tgggaccctc cagagccagg   1440

aggccaaggc tgtgaaaaag accagtctct ttgaggaaga caaagaagat gatctttttg   1500

ccattgccaa ggacagccaa aagaagaccc agagagtgtc actcctcttt gaagacgatg   1560

ttgatagcgg aggctctctg tttggctctc ctcccacatc tgttcctcct gcaacaaaga   1620

aaaaagagac tgtctctgag gcaccacctt tgctgttcag cgatgaagaa gagaaggagg   1680

cacaacttgg agtgaagtct gtggataaga aggttgagag tgccaaggag tcattaaaat   1740

ttgggagaac tgatgtggct gagtcagaaa aggaaggact tttgactaga tctgctcagg   1800

aaacagtcaa gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc   1860

ctagaaccaa aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa   1920

acattatcca ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca   1980

agagcacagg tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca   2040

atgacccaga tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg   2100

ttgggagcct gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc   2160

ctttggtaca agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa   2220

accagaaaca tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa   2280

cacctcaggc aaatttagcg atcaacccag cggccttgct gcccacagcg gcttcccaga   2340

tctctgaagt aaagcctgtt ttgccagaat tggcttttcc ttcatctgaa cacagaagga   2400

gccacggtct ggaaagtgtg cctgtccttc ccgggagtgg ggaggccggt gtgagttttg   2460

atcttccagc tcaggcagac accttacaca gtgcaaacaa gagccgtgtc aagatgagag   2520

ggaagcgtag accgcagacc cgtgcagcta ggcggctggc tgctcaggag tccagcgagg   2580

ctgaggacat gagcgtcccc agaggaccca ttgcacagtg ggctgatggc gccatttccc   2640

caaatggcca tcggccacag ctcagagcag ccagtggaga agacagcact gaggaggccc   2700

tggcagctgc cgctgcacct tgggaaggtg gtcctgtgcc tggagtggac acaagcccct   2760

ttgcaaagtc tctgggtcat tccagagggg aggctgacct ttttgattct ggggacattt   2820

tttccacggg cactggatct cagtccgtgg agagaacaaa acccaaggca aagatagcag   2880

agaatcctgc caacccacca gtgggtggta aagcaaagag ccccatgttt cctgctctag   2940

gcgaggccag cagtgatgat gatctctttc agtctgctaa accaaaacca gcaaagaaaa   3000

caaatccctt tcctctcctg gaagatgagg atgacctctt tacagatcag aaagtcaaga   3060

agaatgagac aaaatccagt agtcagcagg atgtcatatt aacaacacaa gatatttttg   3120

aggatgatat atttgctacg gaagcaatta aaccctctca gaaaaccaga gagaaggaga   3180

aaacattgga atctaattta tttgatgata acattgatat ctttgctgac ttaactgtaa   3240

aaccaaaaga aaagtccaaa aagaaagtgg aagccaagtc tatatttgat gatgatatgg   3300

atgacatctt ctccactggt atccaggcta agacaaccaa accaaaaagc cgatctgcac   3360

aggccgcacc tgaaccaaga tttgaacaca aggtgtccaa catctttgat gatcccctga   3420

atgcctttgg aggccagtag agcacacagg gtatccacat gttaccctgc agctacattg   3480

ttgagttagt gatgatattg tatatgctca tggtcttaac tggattacaa aaagcaaata   3540

ctagaacagc tagctcatct tttacccaat gtacttagta tttttctgca ctggtttaat   3600

catgcttaat actacaaaac aaaaataaat atttcacagt ggttggtttg ttttgttttt   3660

aaaccacagt ttgatttagt tagccttgct ggggccataa tatgcttcag ggtgtgtaaa   3720

agaagaaatc tctttgtggc tttcatgggc agggaatctc agagatagca aatgccacct   3780

gaccagaagt ctttgttata tggatgggaa ccctaactta gggcttgggc aggggaaaga   3840

gaaagaagat gagagattat acttcatgag tcttagcaat atgggagcag gttttcactg   3900

aattctgagg gtgcctctgc atgtcctcca aggcaaagtt tggcaaactg tggccccccc   3960

actgtcatat tttgttaata aaattttatt ggaacacaat caca                    4004


<210>  6741
<211>  1127
<212>  PRT
<213>  Homo sapiens

<400>  6741

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser 
                325                 330                 335


Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu 
            340                 345                 350


Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu 
        355                 360                 365


Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp 
    370                 375                 380


Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu 
385                 390                 395                 400


Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser 
                405                 410                 415


Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln 
            420                 425                 430


Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser 
        435                 440                 445


Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys 
    450                 455                 460


Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu 
465                 470                 475                 480


Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu 
                485                 490                 495


Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro 
            500                 505                 510


Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu 
        515                 520                 525


Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu 
    530                 535                 540


Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu 
545                 550                 555                 560


Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu 
                565                 570                 575


Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser 
            580                 585                 590


Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu 
        595                 600                 605


Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile 
    610                 615                 620


Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His 
625                 630                 635                 640


Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His 
                645                 650                 655


Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr 
            660                 665                 670


Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp 
        675                 680                 685


Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val 
    690                 695                 700


Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe 
705                 710                 715                 720


Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly 
                725                 730                 735


Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile Asn Pro Ala 
            740                 745                 750


Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val 
        755                 760                 765


Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly 
    770                 775                 780


Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser 
785                 790                 795                 800


Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser 
                805                 810                 815


Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg 
            820                 825                 830


Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro 
        835                 840                 845


Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly 
    850                 855                 860


His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu 
865                 870                 875                 880


Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly 
                885                 890                 895


Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu 
            900                 905                 910


Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser 
        915                 920                 925


Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro 
    930                 935                 940


Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala 
945                 950                 955                 960


Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro 
                965                 970                 975


Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp 
            980                 985                 990


Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser 
        995                 1000                1005


Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp 
    1010                1015                1020


Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys 
1025                1030                1035                1040


Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe 
                1045                1050                1055


Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu 
            1060                1065                1070


Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly 
        1075                1080                1085


Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala 
    1090                1095                1100


Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro 
1105                1110                1115                1120


Leu Asn Ala Phe Gly Gly Gln 
                1125


<210>  6742
<211>  4067
<212>  DNA
<213>  Homo sapiens

<400>  6742
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggaggacc agtggaatat tcctgcttca cagacccact   1380

tagcatctga cagcaggtct aaaggagaac ccagggattc tgggaccctc cagagccagg   1440

aggccaaggc tgtgaaaaag accagtctct ttgaggaaga caaagaagat gatctttttg   1500

ccattgccaa ggacagccaa aagaagaccc agagagtgtc actcctcttt gaagacgatg   1560

ttgatagcgg aggctctctg tttggctctc ctcccacatc tgttcctcct gcaacaaaga   1620

aaaaagagac tgtctctgag gcaccacctt tgctgttcag cgatgaagaa gagaaggagg   1680

cacaacttgg agtgaagtct gtggataaga aggttgagag tgccaaggag tcattaaaat   1740

ttgggagaac tgatgtggct gagtcagaaa aggaaggact tttgactaga tctgctcagg   1800

aaacagtcaa gcattctgat ttattttctt catcatcccc atgggacaaa ggaaccaagc   1860

ctagaaccaa aactgttctt agcttgtttg atgaggaaga ggataaaatg gaagatcaaa   1920

acattatcca ggctccacag aaagaagtag gaaagggctg cgatcctgat gcccacccca   1980

agagcacagg tgtcttccag gatgaagagc tgcttttcag ccacaagctc caaaaggaca   2040

atgacccaga tgttgacctt tttgctggca ccaaaaaaac caagctgtta gagccaagtg   2100

ttgggagcct gtttggggat gatgaagatg atgatctttt cagctctgcc aagtcccagc   2160

ctttggtaca agagaaaaag agagtagtga aaaaagacca ctctgttaac tctttcaaaa   2220

accagaaaca tcctgaatcc attcaaggta gtaaagaaaa aggcatatgg aagccggaaa   2280

cacctcagga ctcatcaggt ctcgctccat ttaaaaccaa agaaccatcc actcggatcg   2340

ggaagataca agcaaattta gcgatcaacc cagcggcctt gctgcccaca gcggcttccc   2400

agatctctga agtaaagcct gttttgccag aattggcttt tccttcatct gaacacagaa   2460

ggagccacgg tctggaaagt gtgcctgtcc ttcccgggag tggggaggcc ggtgtgagtt   2520

ttgatcttcc agctcaggca gacaccttac acagtgcaaa caagagccgt gtcaagatga   2580

gagggaagcg tagaccgcag acccgtgcag ctaggcggct ggctgctcag gagtccagcg   2640

aggctgagga catgagcgtc cccagaggac ccattgcaca gtgggctgat ggcgccattt   2700

ccccaaatgg ccatcggcca cagctcagag cagccagtgg agaagacagc actgaggagg   2760

ccctggcagc tgccgctgca ccttgggaag gtggtcctgt gcctggagtg gacacaagcc   2820

cctttgcaaa gtctctgggt cattccagag gggaggctga cctttttgat tctggggaca   2880

ttttttccac gggcactgga tctcagtccg tggagagaac aaaacccaag gcaaagatag   2940

cagagaatcc tgccaaccca ccagtgggtg gtaaagcaaa gagccccatg tttcctgctc   3000

taggcgaggc cagcagtgat gatgatctct ttcagtctgc taaaccaaaa ccagcaaaga   3060

aaacaaatcc ctttcctctc ctggaagatg aggatgacct ctttacagat cagaaagtca   3120

agaagaatga gacaaaatcc agtagtcagc aggatgtcat attaacaaca caagatattt   3180

ttgaggatga tatatttgct acggaagcaa ttaaaccctc tcagaaaacc agagagaagg   3240

agaaaacatt ggaatctaat ttatttgatg ataacattga tatctttgct gacttaactg   3300

taaaaccaaa agaaaagtcc aaaaagaaag tggaagccaa gtctatattt gatgatgata   3360

tggatgacat cttctccact ggtatccagg ctaagacaac caaaccaaaa agccgatctg   3420

cacaggccgc acctgaacca agatttgaac acaaggtgtc caacatcttt gatgatcccc   3480

tgaatgcctt tggaggccag tagagcacac agggtatcca catgttaccc tgcagctaca   3540

ttgttgagtt agtgatgata ttgtatatgc tcatggtctt aactggatta caaaaagcaa   3600

atactagaac agctagctca tcttttaccc aatgtactta gtatttttct gcactggttt   3660

aatcatgctt aatactacaa aacaaaaata aatatttcac agtggttggt ttgttttgtt   3720

tttaaaccac agtttgattt agttagcctt gctggggcca taatatgctt cagggtgtgt   3780

aaaagaagaa atctctttgt ggctttcatg ggcagggaat ctcagagata gcaaatgcca   3840

cctgaccaga agtctttgtt atatggatgg gaaccctaac ttagggcttg ggcaggggaa   3900

agagaaagaa gatgagagat tatacttcat gagtcttagc aatatgggag caggttttca   3960

ctgaattctg agggtgcctc tgcatgtcct ccaaggcaaa gtttggcaaa ctgtggcccc   4020

cccactgtca tattttgtta ataaaatttt attggaacac aatcaca                 4067


<210>  6743
<211>  1148
<212>  PRT
<213>  Homo sapiens

<400>  6743

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Val Thr Leu Ser Tyr Ser Lys Asn Leu Lys Pro Ser Ser 
                325                 330                 335


Glu Thr Lys Thr Gln Lys Gly Leu Phe Ser Asp Glu Glu Asp Ser Glu 
            340                 345                 350


Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly Ala Ser Leu 
        355                 360                 365


Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp Asp Glu Asp 
    370                 375                 380


Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys Gln Thr Leu 
385                 390                 395                 400


Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser Glu Leu Ser 
                405                 410                 415


Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu Glu Asp Gln 
            420                 425                 430


Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp Ser Arg Ser 
        435                 440                 445


Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln Glu Ala Lys 
    450                 455                 460


Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu Asp Asp Leu 
465                 470                 475                 480


Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg Val Ser Leu 
                485                 490                 495


Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro 
            500                 505                 510


Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr Val Ser Glu 
        515                 520                 525


Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu Ala Gln Leu 
    530                 535                 540


Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys Glu Ser Leu 
545                 550                 555                 560


Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu Gly Leu Leu 
                565                 570                 575


Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser Ser 
            580                 585                 590


Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val Leu 
        595                 600                 605


Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile Ile 
    610                 615                 620


Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro Asp Ala His 
625                 630                 635                 640


Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu Phe Ser His 
                645                 650                 655


Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe Ala Gly Thr 
            660                 665                 670


Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu Phe Gly Asp 
        675                 680                 685


Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln Pro Leu Val 
    690                 695                 700


Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val Asn Ser Phe 
705                 710                 715                 720


Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys Glu Lys Gly 
                725                 730                 735


Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu Ala Pro Phe 
            740                 745                 750


Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln Ala Asn Leu 
        755                 760                 765


Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser 
    770                 775                 780


Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His 
785                 790                 795                 800


Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly 
                805                 810                 815


Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His 
            820                 825                 830


Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln 
        835                 840                 845


Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu 
    850                 855                 860


Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala 
865                 870                 875                 880


Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu 
                885                 890                 895


Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly 
            900                 905                 910


Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly 
        915                 920                 925


His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser 
    930                 935                 940


Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys 
945                 950                 955                 960


Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser 
                965                 970                 975


Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe 
            980                 985                 990


Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu 
        995                 1000                1005


Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn 
    1010                1015                1020


Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp 
1025                1030                1035                1040


Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln 
                1045                1050                1055


Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp 
            1060                1065                1070


Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser 
        1075                1080                1085


Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp 
    1090                1095                1100


Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg 
1105                1110                1115                1120


Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn 
                1125                1130                1135


Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            1140                1145


<210>  6744
<211>  4032
<212>  DNA
<213>  Homo sapiens

<400>  6744
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggattt gttttcttct caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg   1080

gcaagctccc cacgtcggtt tccctgtttg atgatgaaga tgaagaggat aatctttttg   1140

ggggtacagc tgctaagaag cagacattgt ctctacaagc tcagagagaa gagaaagcaa   1200

aagcctccga gctctccaaa aagaaagcat ctgccctgtt gttcagcagt gatgaggagg   1260

accagtggaa tattcctgct tcacagaccc acttagcatc tgacagcagg tctaaaggag   1320

aacccaggga ttctgggacc ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc   1380

tctttgagga agacaaagaa gatgatcttt ttgccattgc caaggacaga tacatcctac   1440

ctcctattgt tcccgaagtt gtctgtcaag ttttgtgtat ggaaagtaat tcataccttc   1500

atcagatctc aaaagaagct ttacacacac aagaagaagt tgagccaaaa gaagacccag   1560

agagtgtcac tcctctttga agacgatgtt gatagcggag gctctctgtt tggctctcct   1620

cccacatctg ttcctcctgc aacaaagaaa aaagagactg tctctgaggc accacctttg   1680

ctgttcagcg atgaagaaga gaaggaggca caacttggag tgaagtctgt ggataagaag   1740

gttgagagtg ccaaggagtc attaaaattt gggagaactg atgtggctga gtcagaaaag   1800

gaaggacttt tgactagatc tgctcaggaa acagtcaagc attctgattt attttcttca   1860

tcatccccat gggacaaagg aaccaagcct agaaccaaaa ctgttcttag cttgtttgat   1920

gaggaagagg ataaaatgga agatcaaaac attatccagg ctccacagaa agaagtagga   1980

aagggctgcg atcctgatgc ccaccccaag agcacaggtg tcttccagga tgaagagctg   2040

cttttcagcc acaagctcca aaaggacaat gacccagatg ttgacctttt tgctggcacc   2100

aaaaaaacca agctgttaga gccaagtgtt gggagcctgt ttggggatga tgaagatgat   2160

gatcttttca gctctgccaa gtcccagcct ttggtacaag agaaaaagag agtagtgaaa   2220

aaagaccact ctgttaactc tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt   2280

aaagaaaaag gcatatggaa gccggaaaca cctcaggcaa atttagcgat caacccagcg   2340

gccttgctgc ccacagcggc ttcccagatc tctgaagtaa agcctgtttt gccagaattg   2400

gcttttcctt catctgaaca cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc   2460

gggagtgggg aggccggtgt gagttttgat cttccagctc aggcagacac cttacacagt   2520

gcaaacaaga gccgtgtcaa gatgagaggg aagcgtagac cgcagacccg tgcagctagg   2580

cggctggctg ctcaggagtc cagcgaggct gaggacatga gcgtccccag aggacccatt   2640

gcacagtggg ctgatggcgc catttcccca aatggccatc ggccacagct cagagcagcc   2700

agtggagaag acagcactga ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt   2760

cctgtgcctg gagtggacac aagccccttt gcaaagtctc tgggtcattc cagaggggag   2820

gctgaccttt ttgattctgg ggacattttt tccacgggca ctggatctca gtccgtggag   2880

agaacaaaac ccaaggcaaa gatagcagag aatcctgcca acccaccagt gggtggtaaa   2940

gcaaagagcc ccatgtttcc tgctctaggc gaggccagca gtgatgatga tctctttcag   3000

tctgctaaac caaaaccagc aaagaaaaca aatccctttc ctctcctgga agatgaggat   3060

gacctcttta cagatcagaa agtcaagaag aatgagacaa aatccagtag tcagcaggat   3120

gtcatattaa caacacaaga tatttttgag gatgatatat ttgctacgga agcaattaaa   3180

ccctctcaga aaaccagaga gaaggagaaa acattggaat ctaatttatt tgatgataac   3240

attgatatct ttgctgactt aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa   3300

gccaagtcta tatttgatga tgatatggat gacatcttct ccactggtat ccaggctaag   3360

acaaccaaac caaaaagccg atctgcacag gccgcacctg aaccaagatt tgaacacaag   3420

gtgtccaaca tctttgatga tcccctgaat gcctttggag gccagtagag cacacagggt   3480

atccacatgt taccctgcag ctacattgtt gagttagtga tgatattgta tatgctcatg   3540

gtcttaactg gattacaaaa agcaaatact agaacagcta gctcatcttt tacccaatgt   3600

acttagtatt tttctgcact ggtttaatca tgcttaatac tacaaaacaa aaataaatat   3660

ttcacagtgg ttggtttgtt ttgtttttaa accacagttt gatttagtta gccttgctgg   3720

ggccataata tgcttcaggg tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag   3780

ggaatctcag agatagcaaa tgccacctga ccagaagtct ttgttatatg gatgggaacc   3840

ctaacttagg gcttgggcag gggaaagaga aagaagatga gagattatac ttcatgagtc   3900

ttagcaatat gggagcaggt tttcactgaa ttctgagggt gcctctgcat gtcctccaag   3960

gcaaagtttg gcaaactgtg gcccccccac tgtcatattt tgttaataaa attttattgg   4020

aacacaatca ca                                                       4032


<210>  6745
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6745

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6746
<211>  3681
<212>  DNA
<213>  Homo sapiens

<400>  6746
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggagccaa aagaagaccc agagagtgtc actcctcttt   1380

gaagacgatg ttgatagcgg aggctctctg tttggctctc ctcccacatc tgttcctcct   1440

gcaacaaagg aaggactttt gactagatct gctcaggaaa cagtcaagca ttctgattta   1500

ttttcttcat catccccatg ggacaaagga accaagccta gaaccaaaac tgttcttagc   1560

ttgtttgatg aggaagagga taaaatggaa gatcaaaaca ttatccaggc tccacagaaa   1620

gaagtaggaa agggctgcga tcctgatgcc caccccaaga gcacaggtgt cttccaggat   1680

gaagagctgc ttttcagcca caagctccaa aaggacaatg acccagatgt tgaccttttt   1740

gctggcacca aaaaaaccaa gctgttagag ccaagtgttg ggagcctgtt tggggatgat   1800

gaagatgatg atcttttcag ctctgccaag tcccagcctt tggtacaaga gaaaaagaga   1860

gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc agaaacatcc tgaatccatt   1920

caaggtagta aagaaaaagg catatggaag ccggaaacac ctcaggcaaa tttagcgatc   1980

aacccagcgg ccttgctgcc cacagcggct tcccagatct ctgaagtaaa gcctgttttg   2040

ccagaattgg cttttccttc atctgaacac agaaggagcc acggtctgga aagtgtgcct   2100

gtccttcccg ggagtgggga ggccggtgtg agttttgatc ttccagctca ggcagacacc   2160

ttacacagtg caaacaagag ccgtgtcaag atgagaggga agcgtagacc gcagacccgt   2220

gcagctaggc ggctggctgc tcaggagtcc agcgaggctg aggacatgag cgtccccaga   2280

ggacccattg cacagtgggc tgatggcgcc atttccccaa atggccatcg gccacagctc   2340

agagcagcca gtggagaaga cagcactgag gaggccctgg cagctgccgc tgcaccttgg   2400

gaaggtggtc ctgtgcctgg agtggacaca agcccctttg caaagtctct gggtcattcc   2460

agaggggagg ctgacctttt tgattctggg gacatttttt ccacgggcac tggatctcag   2520

tccgtggaga gaacaaaacc caaggcaaag atagcagaga atcctgccaa cccaccagtg   2580

ggtggtaaag caaagagccc catgtttcct gctctaggcg aggccagcag tgatgatgat   2640

ctctttcagt ctgctaaacc aaaaccagca aagaaaacaa atccctttcc tctcctggaa   2700

gatgaggatg acctctttac agatcagaaa gtcaagaaga atgagacaaa atccagtagt   2760

cagcaggatg tcatattaac aacacaagat atttttgagg atgatatatt tgctacggaa   2820

gcaattaaac cctctcagaa aaccagagag aaggagaaaa cattggaatc taatttattt   2880

gatgataaca ttgatatctt tgctgactta actgtaaaac caaaagaaaa gtccaaaaag   2940

aaagtggaag ccaagtctat atttgatgat gatatggatg acatcttctc cactggtatc   3000

caggctaaga caaccaaacc aaaaagccga tctgcacagg ccgcacctga accaagattt   3060

gaacacaagg tgtccaacat ctttgatgat cccctgaatg cctttggagg ccagtagagc   3120

acacagggta tccacatgtt accctgcagc tacattgttg agttagtgat gatattgtat   3180

atgctcatgg tcttaactgg attacaaaaa gcaaatacta gaacagctag ctcatctttt   3240

acccaatgta cttagtattt ttctgcactg gtttaatcat gcttaatact acaaaacaaa   3300

aataaatatt tcacagtggt tggtttgttt tgtttttaaa ccacagtttg atttagttag   3360

ccttgctggg gccataatat gcttcagggt gtgtaaaaga agaaatctct ttgtggcttt   3420

catgggcagg gaatctcaga gatagcaaat gccacctgac cagaagtctt tgttatatgg   3480

atgggaaccc taacttaggg cttgggcagg ggaaagagaa agaagatgag agattatact   3540

tcatgagtct tagcaatatg ggagcaggtt ttcactgaat tctgagggtg cctctgcatg   3600

tcctccaagg caaagtttgg caaactgtgg cccccccact gtcatatttt gttaataaaa   3660

ttttattgga acacaatcac a                                             3681


<210>  6747
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6747

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6748
<211>  3744
<212>  DNA
<213>  Homo sapiens

<400>  6748
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggttac cttatcttac agcaaaaatc tcaagccctc atcagaaaca aagactcaaa   1080

aaggcttatt ttcagatgag gaggactctg aggatttgtt ttcttctcaa agtgcgagta   1140

acttaaaagg tgcatctctg ctgcctggca agctccccac gtcggtttcc ctgtttgatg   1200

atgaagatga agaggataat ctttttgggg gtacagctgc taagaagcag acattgtctc   1260

tacaagctca gagagaagag aaagcaaaag cctccgagct ctccaaaaag aaagcatctg   1320

ccctgttgtt cagcagtgat gaggagccaa aagaagaccc agagagtgtc actcctcttt   1380

gaagacgatg ttgatagcgg aggctctctg tttggctctc ctcccacatc tgttcctcct   1440

gcaacaaagg aaggactttt gactagatct gctcaggaaa cagtcaagca ttctgattta   1500

ttttcttcat catccccatg ggacaaagga accaagccta gaaccaaaac tgttcttagc   1560

ttgtttgatg aggaagagga taaaatggaa gatcaaaaca ttatccaggc tccacagaaa   1620

gaagtaggaa agggctgcga tcctgatgcc caccccaaga gcacaggtgt cttccaggat   1680

gaagagctgc ttttcagcca caagctccaa aaggacaatg acccagatgt tgaccttttt   1740

gctggcacca aaaaaaccaa gctgttagag ccaagtgttg ggagcctgtt tggggatgat   1800

gaagatgatg atcttttcag ctctgccaag tcccagcctt tggtacaaga gaaaaagaga   1860

gtagtgaaaa aagaccactc tgttaactct ttcaaaaacc agaaacatcc tgaatccatt   1920

caaggtagta aagaaaaagg catatggaag ccggaaacac ctcaggactc atcaggtctc   1980

gctccattta aaaccaaaga accatccact cggatcggga agatacaagc aaatttagcg   2040

atcaacccag cggccttgct gcccacagcg gcttcccaga tctctgaagt aaagcctgtt   2100

ttgccagaat tggcttttcc ttcatctgaa cacagaagga gccacggtct ggaaagtgtg   2160

cctgtccttc ccgggagtgg ggaggccggt gtgagttttg atcttccagc tcaggcagac   2220

accttacaca gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag accgcagacc   2280

cgtgcagcta ggcggctggc tgctcaggag tccagcgagg ctgaggacat gagcgtcccc   2340

agaggaccca ttgcacagtg ggctgatggc gccatttccc caaatggcca tcggccacag   2400

ctcagagcag ccagtggaga agacagcact gaggaggccc tggcagctgc cgctgcacct   2460

tgggaaggtg gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc tctgggtcat   2520

tccagagggg aggctgacct ttttgattct ggggacattt tttccacggg cactggatct   2580

cagtccgtgg agagaacaaa acccaaggca aagatagcag agaatcctgc caacccacca   2640

gtgggtggta aagcaaagag ccccatgttt cctgctctag gcgaggccag cagtgatgat   2700

gatctctttc agtctgctaa accaaaacca gcaaagaaaa caaatccctt tcctctcctg   2760

gaagatgagg atgacctctt tacagatcag aaagtcaaga agaatgagac aaaatccagt   2820

agtcagcagg atgtcatatt aacaacacaa gatatttttg aggatgatat atttgctacg   2880

gaagcaatta aaccctctca gaaaaccaga gagaaggaga aaacattgga atctaattta   2940

tttgatgata acattgatat ctttgctgac ttaactgtaa aaccaaaaga aaagtccaaa   3000

aagaaagtgg aagccaagtc tatatttgat gatgatatgg atgacatctt ctccactggt   3060

atccaggcta agacaaccaa accaaaaagc cgatctgcac aggccgcacc tgaaccaaga   3120

tttgaacaca aggtgtccaa catctttgat gatcccctga atgcctttgg aggccagtag   3180

agcacacagg gtatccacat gttaccctgc agctacattg ttgagttagt gatgatattg   3240

tatatgctca tggtcttaac tggattacaa aaagcaaata ctagaacagc tagctcatct   3300

tttacccaat gtacttagta tttttctgca ctggtttaat catgcttaat actacaaaac   3360

aaaaataaat atttcacagt ggttggtttg ttttgttttt aaaccacagt ttgatttagt   3420

tagccttgct ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc tctttgtggc   3480

tttcatgggc agggaatctc agagatagca aatgccacct gaccagaagt ctttgttata   3540

tggatgggaa ccctaactta gggcttgggc aggggaaaga gaaagaagat gagagattat   3600

acttcatgag tcttagcaat atgggagcag gttttcactg aattctgagg gtgcctctgc   3660

atgtcctcca aggcaaagtt tggcaaactg tggccccccc actgtcatat tttgttaata   3720

aaattttatt ggaacacaat caca                                          3744


<210>  6749
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6749

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6750
<211>  3980
<212>  DNA
<213>  Homo sapiens

<400>  6750
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggattt gttttcttct caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg   1080

gcaagctccc cacgtcggtt tccctgtttg atgatgaaga tgaagaggat aatctttttg   1140

ggggtacagc tgctaagaag cagacattgt ctctacaagc tcagagagaa gagaaagcaa   1200

aagcctccga gctctccaaa aagaaagcat ctgccctgtt gttcagcagt gatgaggagg   1260

accagtggaa tattcctgct tcacagaccc acttagcatc tgacagcagg tctaaaggag   1320

aacccaggga ttctgggacc ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc   1380

tctttgagga agacaaagaa gatgatcttt ttgccattgc caaggacagc caaaagaaga   1440

cccagagagt gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct   1500

ctcctcccac atctgttcct cctgcaacaa agaaaaaaga gactgtctct gaggcaccac   1560

ctttgctgtt cagcgatgaa gaagagaagg aggcacaact tggagtgaag tctgtggata   1620

agaaggttga gagtgccaag gagtcattaa aatttgggag aactgatgtg gctgagtcag   1680

aaaaggaagg acttttgact agatctgctc aggaaacagt caagcattct gatttatttt   1740

cttcatcatc cccatgggac aaaggaacca agcctagaac caaaactgtt cttagcttgt   1800

ttgatgagga agaggataaa atggaagatc aaaacattat ccaggctcca cagaaagaag   1860

taggaaaggg ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc caggatgaag   1920

agctgctttt cagccacaag ctccaaaagg acaatgaccc agatgttgac ctttttgctg   1980

gcaccaaaaa aaccaagctg ttagagccaa gtgttgggag cctgtttggg gatgatgaag   2040

atgatgatct tttcagctct gccaagtccc agcctttggt acaagagaaa aagagagtag   2100

tgaaaaaaga ccactctgtt aactctttca aaaaccagaa acatcctgaa tccattcaag   2160

gtagtaaaga aaaaggcata tggaagccgg aaacacctca ggactcatca ggtctcgctc   2220

catttaaaac caaagaacca tccactcgga tcgggaagat acaagcaaat ttagcgatca   2280

acccagcggc cttgctgccc acagcggctt cccagatctc tgaagtaaag cctgttttgc   2340

cagaattggc ttttccttca tctgaacaca gaaggagcca cggtctggaa agtgtgcctg   2400

tccttcccgg gagtggggag gccggtgtga gttttgatct tccagctcag gcagacacct   2460

tacacagtgc aaacaagagc cgtgtcaaga tgagagggaa gcgtagaccg cagacccgtg   2520

cagctaggcg gctggctgct caggagtcca gcgaggctga ggacatgagc gtccccagag   2580

gacccattgc acagtgggct gatggcgcca tttccccaaa tggccatcgg ccacagctca   2640

gagcagccag tggagaagac agcactgagg aggccctggc agctgccgct gcaccttggg   2700

aaggtggtcc tgtgcctgga gtggacacaa gcccctttgc aaagtctctg ggtcattcca   2760

gaggggaggc tgaccttttt gattctgggg acattttttc cacgggcact ggatctcagt   2820

ccgtggagag aacaaaaccc aaggcaaaga tagcagagaa tcctgccaac ccaccagtgg   2880

gtggtaaagc aaagagcccc atgtttcctg ctctaggcga ggccagcagt gatgatgatc   2940

tctttcagtc tgctaaacca aaaccagcaa agaaaacaaa tccctttcct ctcctggaag   3000

atgaggatga cctctttaca gatcagaaag tcaagaagaa tgagacaaaa tccagtagtc   3060

agcaggatgt catattaaca acacaagata tttttgagga tgatatattt gctacggaag   3120

caattaaacc ctctcagaaa accagagaga aggagaaaac attggaatct aatttatttg   3180

atgataacat tgatatcttt gctgacttaa ctgtaaaacc aaaagaaaag tccaaaaaga   3240

aagtggaagc caagtctata tttgatgatg atatggatga catcttctcc actggtatcc   3300

aggctaagac aaccaaacca aaaagccgat ctgcacaggc cgcacctgaa ccaagatttg   3360

aacacaaggt gtccaacatc tttgatgatc ccctgaatgc ctttggaggc cagtagagca   3420

cacagggtat ccacatgtta ccctgcagct acattgttga gttagtgatg atattgtata   3480

tgctcatggt cttaactgga ttacaaaaag caaatactag aacagctagc tcatctttta   3540

cccaatgtac ttagtatttt tctgcactgg tttaatcatg cttaatacta caaaacaaaa   3600

ataaatattt cacagtggtt ggtttgtttt gtttttaaac cacagtttga tttagttagc   3660

cttgctgggg ccataatatg cttcagggtg tgtaaaagaa gaaatctctt tgtggctttc   3720

atgggcaggg aatctcagag atagcaaatg ccacctgacc agaagtcttt gttatatgga   3780

tgggaaccct aacttagggc ttgggcaggg gaaagagaaa gaagatgaga gattatactt   3840

catgagtctt agcaatatgg gagcaggttt tcactgaatt ctgagggtgc ctctgcatgt   3900

cctccaaggc aaagtttggc aaactgtggc ccccccactg tcatattttg ttaataaaat   3960

tttattggaa cacaatcaca                                               3980


<210>  6751
<211>  1119
<212>  PRT
<213>  Homo sapiens

<400>  6751

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly 
                325                 330                 335


Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp 
            340                 345                 350


Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys 
        355                 360                 365


Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser 
    370                 375                 380


Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu 
385                 390                 395                 400


Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp 
                405                 410                 415


Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln 
            420                 425                 430


Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu 
        435                 440                 445


Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg 
    450                 455                 460


Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe 
465                 470                 475                 480


Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr 
                485                 490                 495


Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu 
            500                 505                 510


Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys 
        515                 520                 525


Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu 
    530                 535                 540


Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu 
545                 550                 555                 560


Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys 
                565                 570                 575


Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln 
            580                 585                 590


Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro 
        595                 600                 605


Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu 
    610                 615                 620


Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe 
625                 630                 635                 640


Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu 
                645                 650                 655


Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln 
            660                 665                 670


Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val 
        675                 680                 685


Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys 
    690                 695                 700


Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp Ser Ser Gly Leu 
705                 710                 715                 720


Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile Gly Lys Ile Gln 
                725                 730                 735


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            740                 745                 750


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        755                 760                 765


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    770                 775                 780


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
785                 790                 795                 800


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                805                 810                 815


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            820                 825                 830


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        835                 840                 845


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    850                 855                 860


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
865                 870                 875                 880


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                885                 890                 895


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            900                 905                 910


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        915                 920                 925


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    930                 935                 940


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
945                 950                 955                 960


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                965                 970                 975


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            980                 985                 990


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        995                 1000                1005


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    1010                1015                1020


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
1025                1030                1035                1040


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                1045                1050                1055


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            1060                1065                1070


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        1075                1080                1085


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    1090                1095                1100


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
1105                1110                1115


<210>  6752
<211>  3917
<212>  DNA
<213>  Homo sapiens

<400>  6752
tacaggatct atacattgat cgtcctttac catatctcat tgggtcaaag ctgttcatgg     60

aacaagaaga tgtaggtctt ggagagctgt ccagtgaaga aggctctgta ggcagtgatc    120

gtggcagtat tgtggacact gaggaagaga aagaagagga ggagtcagat gaagattttg    180

cccatcacag tgacaatgaa caaaaccagc acaccacaca aatgagtgat gaggaagagg    240

atgatgatgg ctgtgacctt tttgctgact ctgagaagga ggaggaagat attgaggaca    300

ttgaagaaaa tactagacct aaaagaagca gacctacatc gtttgcagat gagctggctg    360

cccgcatcaa gggggatgcc atgggtcgag tggacgagga gccgacaacc ttaccctcag    420

gagaagcaaa acctcggaag acactcaaag agaagaagga aaggagaact ccttcagacg    480

atgaagagga taacttattc gcacccccca agctgaccga cgaggacttc tcgccatttg    540

gctctggagg tggcctgttc agtggcggca aggggctatt tgatgatgag gacgaggaga    600

gtgacctctt cacggaagcc tcccaggatc ggcaagctgg agcctctgtt aaggaggagt    660

cttcatcatc caaacctgga aagaaaatcc cagcaggagc tgtttctgta tttttaggag    720

acacggatgt gtttggtgct gcctccgttc catcactgaa ggagccacag aagcctgagc    780

agcccactcc aaggaaaagc ccctatggtc cccctcccac tggcctcttt gatgatgatg    840

atggtgatga tgatgacgac tttttctcgg caccccacag caaaccttct aaaacacgca    900

aagtccaatc cactgccgat atctttggtg acgaagaagg agatctgttc aaagaaaaag    960

ccgtagcatc gccagaagcc actgtgagtc agacagatga aaataaagca agagcagaaa   1020

aaaaggattt gttttcttct caaagtgcga gtaacttaaa aggtgcatct ctgctgcctg   1080

gcaagctccc cacgtcggtt tccctgtttg atgatgaaga tgaagaggat aatctttttg   1140

ggggtacagc tgctaagaag cagacattgt ctctacaagc tcagagagaa gagaaagcaa   1200

aagcctccga gctctccaaa aagaaagcat ctgccctgtt gttcagcagt gatgaggagg   1260

accagtggaa tattcctgct tcacagaccc acttagcatc tgacagcagg tctaaaggag   1320

aacccaggga ttctgggacc ctccagagcc aggaggccaa ggctgtgaaa aagaccagtc   1380

tctttgagga agacaaagaa gatgatcttt ttgccattgc caaggacagc caaaagaaga   1440

cccagagagt gtcactcctc tttgaagacg atgttgatag cggaggctct ctgtttggct   1500

ctcctcccac atctgttcct cctgcaacaa agaaaaaaga gactgtctct gaggcaccac   1560

ctttgctgtt cagcgatgaa gaagagaagg aggcacaact tggagtgaag tctgtggata   1620

agaaggttga gagtgccaag gagtcattaa aatttgggag aactgatgtg gctgagtcag   1680

aaaaggaagg acttttgact agatctgctc aggaaacagt caagcattct gatttatttt   1740

cttcatcatc cccatgggac aaaggaacca agcctagaac caaaactgtt cttagcttgt   1800

ttgatgagga agaggataaa atggaagatc aaaacattat ccaggctcca cagaaagaag   1860

taggaaaggg ctgcgatcct gatgcccacc ccaagagcac aggtgtcttc caggatgaag   1920

agctgctttt cagccacaag ctccaaaagg acaatgaccc agatgttgac ctttttgctg   1980

gcaccaaaaa aaccaagctg ttagagccaa gtgttgggag cctgtttggg gatgatgaag   2040

atgatgatct tttcagctct gccaagtccc agcctttggt acaagagaaa aagagagtag   2100

tgaaaaaaga ccactctgtt aactctttca aaaaccagaa acatcctgaa tccattcaag   2160

gtagtaaaga aaaaggcata tggaagccgg aaacacctca ggcaaattta gcgatcaacc   2220

cagcggcctt gctgcccaca gcggcttccc agatctctga agtaaagcct gttttgccag   2280

aattggcttt tccttcatct gaacacagaa ggagccacgg tctggaaagt gtgcctgtcc   2340

ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc agctcaggca gacaccttac   2400

acagtgcaaa caagagccgt gtcaagatga gagggaagcg tagaccgcag acccgtgcag   2460

ctaggcggct ggctgctcag gagtccagcg aggctgagga catgagcgtc cccagaggac   2520

ccattgcaca gtgggctgat ggcgccattt ccccaaatgg ccatcggcca cagctcagag   2580

cagccagtgg agaagacagc actgaggagg ccctggcagc tgccgctgca ccttgggaag   2640

gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa gtctctgggt cattccagag   2700

gggaggctga cctttttgat tctggggaca ttttttccac gggcactgga tctcagtccg   2760

tggagagaac aaaacccaag gcaaagatag cagagaatcc tgccaaccca ccagtgggtg   2820

gtaaagcaaa gagccccatg tttcctgctc taggcgaggc cagcagtgat gatgatctct   2880

ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc ctttcctctc ctggaagatg   2940

aggatgacct ctttacagat cagaaagtca agaagaatga gacaaaatcc agtagtcagc   3000

aggatgtcat attaacaaca caagatattt ttgaggatga tatatttgct acggaagcaa   3060

ttaaaccctc tcagaaaacc agagagaagg agaaaacatt ggaatctaat ttatttgatg   3120

ataacattga tatctttgct gacttaactg taaaaccaaa agaaaagtcc aaaaagaaag   3180

tggaagccaa gtctatattt gatgatgata tggatgacat cttctccact ggtatccagg   3240

ctaagacaac caaaccaaaa agccgatctg cacaggccgc acctgaacca agatttgaac   3300

acaaggtgtc caacatcttt gatgatcccc tgaatgcctt tggaggccag tagagcacac   3360

agggtatcca catgttaccc tgcagctaca ttgttgagtt agtgatgata ttgtatatgc   3420

tcatggtctt aactggatta caaaaagcaa atactagaac agctagctca tcttttaccc   3480

aatgtactta gtatttttct gcactggttt aatcatgctt aatactacaa aacaaaaata   3540

aatatttcac agtggttggt ttgttttgtt tttaaaccac agtttgattt agttagcctt   3600

gctggggcca taatatgctt cagggtgtgt aaaagaagaa atctctttgt ggctttcatg   3660

ggcagggaat ctcagagata gcaaatgcca cctgaccaga agtctttgtt atatggatgg   3720

gaaccctaac ttagggcttg ggcaggggaa agagaaagaa gatgagagat tatacttcat   3780

gagtcttagc aatatgggag caggttttca ctgaattctg agggtgcctc tgcatgtcct   3840

ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca tattttgtta ataaaatttt   3900

attggaacac aatcaca                                                  3917


<210>  6753
<211>  1098
<212>  PRT
<213>  Homo sapiens

<400>  6753

Met Glu Gln Glu Asp Val Gly Leu Gly Glu Leu Ser Ser Glu Glu Gly 
1               5                   10                  15


Ser Val Gly Ser Asp Arg Gly Ser Ile Val Asp Thr Glu Glu Glu Lys 
            20                  25                  30


Glu Glu Glu Glu Ser Asp Glu Asp Phe Ala His His Ser Asp Asn Glu 
        35                  40                  45


Gln Asn Gln His Thr Thr Gln Met Ser Asp Glu Glu Glu Asp Asp Asp 
    50                  55                  60


Gly Cys Asp Leu Phe Ala Asp Ser Glu Lys Glu Glu Glu Asp Ile Glu 
65                  70                  75                  80


Asp Ile Glu Glu Asn Thr Arg Pro Lys Arg Ser Arg Pro Thr Ser Phe 
                85                  90                  95


Ala Asp Glu Leu Ala Ala Arg Ile Lys Gly Asp Ala Met Gly Arg Val 
            100                 105                 110


Asp Glu Glu Pro Thr Thr Leu Pro Ser Gly Glu Ala Lys Pro Arg Lys 
        115                 120                 125


Thr Leu Lys Glu Lys Lys Glu Arg Arg Thr Pro Ser Asp Asp Glu Glu 
    130                 135                 140


Asp Asn Leu Phe Ala Pro Pro Lys Leu Thr Asp Glu Asp Phe Ser Pro 
145                 150                 155                 160


Phe Gly Ser Gly Gly Gly Leu Phe Ser Gly Gly Lys Gly Leu Phe Asp 
                165                 170                 175


Asp Glu Asp Glu Glu Ser Asp Leu Phe Thr Glu Ala Ser Gln Asp Arg 
            180                 185                 190


Gln Ala Gly Ala Ser Val Lys Glu Glu Ser Ser Ser Ser Lys Pro Gly 
        195                 200                 205


Lys Lys Ile Pro Ala Gly Ala Val Ser Val Phe Leu Gly Asp Thr Asp 
    210                 215                 220


Val Phe Gly Ala Ala Ser Val Pro Ser Leu Lys Glu Pro Gln Lys Pro 
225                 230                 235                 240


Glu Gln Pro Thr Pro Arg Lys Ser Pro Tyr Gly Pro Pro Pro Thr Gly 
                245                 250                 255


Leu Phe Asp Asp Asp Asp Gly Asp Asp Asp Asp Asp Phe Phe Ser Ala 
            260                 265                 270


Pro His Ser Lys Pro Ser Lys Thr Arg Lys Val Gln Ser Thr Ala Asp 
        275                 280                 285


Ile Phe Gly Asp Glu Glu Gly Asp Leu Phe Lys Glu Lys Ala Val Ala 
    290                 295                 300


Ser Pro Glu Ala Thr Val Ser Gln Thr Asp Glu Asn Lys Ala Arg Ala 
305                 310                 315                 320


Glu Lys Lys Asp Leu Phe Ser Ser Gln Ser Ala Ser Asn Leu Lys Gly 
                325                 330                 335


Ala Ser Leu Leu Pro Gly Lys Leu Pro Thr Ser Val Ser Leu Phe Asp 
            340                 345                 350


Asp Glu Asp Glu Glu Asp Asn Leu Phe Gly Gly Thr Ala Ala Lys Lys 
        355                 360                 365


Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys Ala Ser 
    370                 375                 380


Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser Asp Glu 
385                 390                 395                 400


Glu Asp Gln Trp Asn Ile Pro Ala Ser Gln Thr His Leu Ala Ser Asp 
                405                 410                 415


Ser Arg Ser Lys Gly Glu Pro Arg Asp Ser Gly Thr Leu Gln Ser Gln 
            420                 425                 430


Glu Ala Lys Ala Val Lys Lys Thr Ser Leu Phe Glu Glu Asp Lys Glu 
        435                 440                 445


Asp Asp Leu Phe Ala Ile Ala Lys Asp Ser Gln Lys Lys Thr Gln Arg 
    450                 455                 460


Val Ser Leu Leu Phe Glu Asp Asp Val Asp Ser Gly Gly Ser Leu Phe 
465                 470                 475                 480


Gly Ser Pro Pro Thr Ser Val Pro Pro Ala Thr Lys Lys Lys Glu Thr 
                485                 490                 495


Val Ser Glu Ala Pro Pro Leu Leu Phe Ser Asp Glu Glu Glu Lys Glu 
            500                 505                 510


Ala Gln Leu Gly Val Lys Ser Val Asp Lys Lys Val Glu Ser Ala Lys 
        515                 520                 525


Glu Ser Leu Lys Phe Gly Arg Thr Asp Val Ala Glu Ser Glu Lys Glu 
    530                 535                 540


Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu 
545                 550                 555                 560


Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys 
                565                 570                 575


Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln 
            580                 585                 590


Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Cys Asp Pro 
        595                 600                 605


Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp Glu Glu Leu Leu 
    610                 615                 620


Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp Val Asp Leu Phe 
625                 630                 635                 640


Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser Val Gly Ser Leu 
                645                 650                 655


Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser Ala Lys Ser Gln 
            660                 665                 670


Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys Asp His Ser Val 
        675                 680                 685


Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile Gln Gly Ser Lys 
    690                 695                 700


Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala Asn Leu Ala Ile 
705                 710                 715                 720


Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val 
                725                 730                 735


Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg 
            740                 745                 750


Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala 
        755                 760                 765


Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala 
    770                 775                 780


Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg 
785                 790                 795                 800


Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met 
                805                 810                 815


Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser 
            820                 825                 830


Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser 
        835                 840                 845


Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro 
    850                 855                 860


Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser 
865                 870                 875                 880


Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly 
                885                 890                 895


Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala 
            900                 905                 910


Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met 
        915                 920                 925


Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser 
    930                 935                 940


Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu 
945                 950                 955                 960


Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr 
                965                 970                 975


Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe 
            980                 985                 990


Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr 
        995                 1000                1005


Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile 
    1010                1015                1020


Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys 
1025                1030                1035                1040


Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe 
                1045                1050                1055


Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala 
            1060                1065                1070


Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe 
        1075                1080                1085


Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
    1090                1095


<210>  6754
<211>  424
<212>  DNA
<213>  Homo sapiens

<400>  6754
ggaggagcct aaaggctgac agtatctctt ctttagctta ataactagta gttctaattt     60

ggtattttat actcttagca caccacacaa atgagtgatg aggaagagga tgatgatggc    120

tgtgaccttt ttgctgactc tgagaaggag gaggaagata ttgaggacat tgaagaaaat    180

actagaccta aaagaagcag acctacatcg tttgcagatg agctggctgc ccgcatcaag    240

ggggatgcca tgggtcgagt ggacgaggag ccgacaagtg agccccagcc acgttgatgg    300

ggagtagggg aggagtagtg cagggccctc tgctggcttc accaaaggcg gatttctctt    360

tttattagta attactacat atatttatta gtaattgcta catataattt aaattgtagc    420

gctt                                                                 424


<210>  6755
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  6755

Met Arg Lys Arg Met Met Met Ala Val Thr Phe Leu Leu Thr Leu Arg 
1               5                   10                  15


Arg Arg Arg Lys Ile Leu Arg Thr Leu Lys Lys Ile Leu Asp Leu Lys 
            20                  25                  30


Glu Ala Asp Leu His Arg Leu Gln Met Ser Trp Leu Pro Ala Ser Arg 
        35                  40                  45


Gly Met Pro Trp Val Glu Trp Thr Arg Ser Arg Gln Val Ser Pro Ser 
    50                  55                  60


His Val Asp Gly Glu 
65


<210>  6756
<211>  3779
<212>  DNA
<213>  Homo sapiens

<400>  6756
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat agcggaggct   1440

ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaaggaagga cttttgacta   1500

gatctgctca ggaaacagtc aagcattctg atttattttc ttcatcatcc ccatgggaca   1560

aaggaaccaa gcctagaacc aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa   1620

tggaagatca aaacattatc caggctccac agaaagaagt aggaaagggc tgcgatcctg   1680

atgcccaccc caagagcaca ggtgtcttcc aggatgaaga gctgcttttc agccacaagc   1740

tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa accaagctgt   1800

tagagccaag tgttgggagc ctgtttgggg atgatgaaga tgatgatctt ttcagctctg   1860

ccaagtccca gcctttggta caagagaaaa agagagtagt gaaaaaagac cactctgtta   1920

actctttcaa aaaccagaaa catcctgaat ccattcaagg tagtaaagaa aaaggcatat   1980

ggaagccgga aacacctcag gactcatcag gtctcgctcc atttaaaacc aaagaaccat   2040

ccactcggat cgggaagata caagcaaatt tagcgatcaa cccagcggcc ttgctgccca   2100

cagcggcttc ccagatctct gaagtaaagc ctgttttgcc agaattggct tttccttcat   2160

ctgaacacag aaggagccac ggtctggaaa gtgtgcctgt ccttcccggg agtggggagg   2220

ccggtgtgag ttttgatctt ccagctcagg cagacacctt acacagtgca aacaagagcc   2280

gtgtcaagat gagagggaag cgtagaccgc agacccgtgc agctaggcgg ctggctgctc   2340

aggagtccag cgaggctgag gacatgagcg tccccagagg acccattgca cagtgggctg   2400

atggcgccat ttccccaaat ggccatcggc cacagctcag agcagccagt ggagaagaca   2460

gcactgagga ggccctggca gctgccgctg caccttggga aggtggtcct gtgcctggag   2520

tggacacaag cccctttgca aagtctctgg gtcattccag aggggaggct gacctttttg   2580

attctgggga cattttttcc acgggcactg gatctcagtc cgtggagaga acaaaaccca   2640

aggcaaagat agcagagaat cctgccaacc caccagtggg tggtaaagca aagagcccca   2700

tgtttcctgc tctaggcgag gccagcagtg atgatgatct ctttcagtct gctaaaccaa   2760

aaccagcaaa gaaaacaaat ccctttcctc tcctggaaga tgaggatgac ctctttacag   2820

atcagaaagt caagaagaat gagacaaaat ccagtagtca gcaggatgtc atattaacaa   2880

cacaagatat ttttgaggat gatatatttg ctacggaagc aattaaaccc tctcagaaaa   2940

ccagagagaa ggagaaaaca ttggaatcta atttatttga tgataacatt gatatctttg   3000

ctgacttaac tgtaaaacca aaagaaaagt ccaaaaagaa agtggaagcc aagtctatat   3060

ttgatgatga tatggatgac atcttctcca ctggtatcca ggctaagaca accaaaccaa   3120

aaagccgatc tgcacaggcc gcacctgaac caagatttga acacaaggtg tccaacatct   3180

ttgatgatcc cctgaatgcc tttggaggcc agtagagcac acagggtatc cacatgttac   3240

cctgcagcta cattgttgag ttagtgatga tattgtatat gctcatggtc ttaactggat   3300

tacaaaaagc aaatactaga acagctagct catcttttac ccaatgtact tagtattttt   3360

ctgcactggt ttaatcatgc ttaatactac aaaacaaaaa taaatatttc acagtggttg   3420

gtttgttttg tttttaaacc acagtttgat ttagttagcc ttgctggggc cataatatgc   3480

ttcagggtgt gtaaaagaag aaatctcttt gtggctttca tgggcaggga atctcagaga   3540

tagcaaatgc cacctgacca gaagtctttg ttatatggat gggaacccta acttagggct   3600

tgggcagggg aaagagaaag aagatgagag attatacttc atgagtctta gcaatatggg   3660

agcaggtttt cactgaattc tgagggtgcc tctgcatgtc ctccaaggca aagtttggca   3720

aactgtggcc cccccactgt catattttgt taataaaatt ttattggaac acaatcaca    3779


<210>  6757
<211>  660
<212>  PRT
<213>  Homo sapiens

<400>  6757

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg 
            260                 265                 270


Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu 
        275                 280                 285


Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu 
    290                 295                 300


Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser 
305                 310                 315                 320


Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu 
                325                 330                 335


Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys 
            340                 345                 350


Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
        355                 360                 365


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
    370                 375                 380


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
385                 390                 395                 400


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
                405                 410                 415


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
            420                 425                 430


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
        435                 440                 445


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
    450                 455                 460


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
465                 470                 475                 480


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
                485                 490                 495


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
            500                 505                 510


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
        515                 520                 525


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
    530                 535                 540


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
545                 550                 555                 560


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
                565                 570                 575


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
            580                 585                 590


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
        595                 600                 605


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
    610                 615                 620


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
625                 630                 635                 640


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
                645                 650                 655


Phe Gly Gly Gln 
            660


<210>  6758
<211>  4130
<212>  DNA
<213>  Homo sapiens

<400>  6758
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gatttgtttt cttctcaaag   1080

tgcgagtaac ttaaaaggtg catctctgct gcctggcaag ctccccacgt cggtttccct   1140

gtttgatgat gaagatgaag aggataatct ttttgggggt acagctgcta agaagcagac   1200

attgtctcta caagctcaga gagaagagaa agcaaaagcc tccgagctct ccaaaaagaa   1260

agcatctgcc ctgttgttca gcagtgatga ggaggaccag tggaatattc ctgcttcaca   1320

gacccactta gcatctgaca gcaggtctaa aggagaaccc agggattctg ggaccctcca   1380

gagccaggag gccaaggctg tgaaaaagac cagtctcttt gaggaagaca aagaagatga   1440

tctttttgcc attgccaagg acagatacat cctacctcct attgttcccg aagttgtctg   1500

tcaagttttg tgtatggaaa gtaattcata ccttcatcag atctcaaaag aagctttaca   1560

cacacaagaa gaagttgagc caaaagaaga cccagagagt gtcactcctc tttgaagacg   1620

atgttgatag cggaggctct ctgtttggct ctcctcccac atctgttcct cctgcaacaa   1680

agaaaaaaga gactgtctct gaggcaccac ctttgctgtt cagcgatgaa gaagagaagg   1740

aggcacaact tggagtgaag tctgtggata agaaggttga gagtgccaag gagtcattaa   1800

aatttgggag aactgatgtg gctgagtcag aaaaggaagg acttttgact agatctgctc   1860

aggaaacagt caagcattct gatttatttt cttcatcatc cccatgggac aaaggaacca   1920

agcctagaac caaaactgtt cttagcttgt ttgatgagga agaggataaa atggaagatc   1980

aaaacattat ccaggctcca cagaaagaag taggaaaggg ctgcgatcct gatgcccacc   2040

ccaagagcac aggtgtcttc caggatgaag agctgctttt cagccacaag ctccaaaagg   2100

acaatgaccc agatgttgac ctttttgctg gcaccaaaaa aaccaagctg ttagagccaa   2160

gtgttgggag cctgtttggg gatgatgaag atgatgatct tttcagctct gccaagtccc   2220

agcctttggt acaagagaaa aagagagtag tgaaaaaaga ccactctgtt aactctttca   2280

aaaaccagaa acatcctgaa tccattcaag gtagtaaaga aaaaggcata tggaagccgg   2340

aaacacctca ggactcatca ggtctcgctc catttaaaac caaagaacca tccactcgga   2400

tcgggaagat acaagcaaat ttagcgatca acccagcggc cttgctgccc acagcggctt   2460

cccagatctc tgaagtaaag cctgttttgc cagaattggc ttttccttca tctgaacaca   2520

gaaggagcca cggtctggaa agtgtgcctg tccttcccgg gagtggggag gccggtgtga   2580

gttttgatct tccagctcag gcagacacct tacacagtgc aaacaagagc cgtgtcaaga   2640

tgagagggaa gcgtagaccg cagacccgtg cagctaggcg gctggctgct caggagtcca   2700

gcgaggctga ggacatgagc gtccccagag gacccattgc acagtgggct gatggcgcca   2760

tttccccaaa tggccatcgg ccacagctca gagcagccag tggagaagac agcactgagg   2820

aggccctggc agctgccgct gcaccttggg aaggtggtcc tgtgcctgga gtggacacaa   2880

gcccctttgc aaagtctctg ggtcattcca gaggggaggc tgaccttttt gattctgggg   2940

acattttttc cacgggcact ggatctcagt ccgtggagag aacaaaaccc aaggcaaaga   3000

tagcagagaa tcctgccaac ccaccagtgg gtggtaaagc aaagagcccc atgtttcctg   3060

ctctaggcga ggccagcagt gatgatgatc tctttcagtc tgctaaacca aaaccagcaa   3120

agaaaacaaa tccctttcct ctcctggaag atgaggatga cctctttaca gatcagaaag   3180

tcaagaagaa tgagacaaaa tccagtagtc agcaggatgt catattaaca acacaagata   3240

tttttgagga tgatatattt gctacggaag caattaaacc ctctcagaaa accagagaga   3300

aggagaaaac attggaatct aatttatttg atgataacat tgatatcttt gctgacttaa   3360

ctgtaaaacc aaaagaaaag tccaaaaaga aagtggaagc caagtctata tttgatgatg   3420

atatggatga catcttctcc actggtatcc aggctaagac aaccaaacca aaaagccgat   3480

ctgcacaggc cgcacctgaa ccaagatttg aacacaaggt gtccaacatc tttgatgatc   3540

ccctgaatgc ctttggaggc cagtagagca cacagggtat ccacatgtta ccctgcagct   3600

acattgttga gttagtgatg atattgtata tgctcatggt cttaactgga ttacaaaaag   3660

caaatactag aacagctagc tcatctttta cccaatgtac ttagtatttt tctgcactgg   3720

tttaatcatg cttaatacta caaaacaaaa ataaatattt cacagtggtt ggtttgtttt   3780

gtttttaaac cacagtttga tttagttagc cttgctgggg ccataatatg cttcagggtg   3840

tgtaaaagaa gaaatctctt tgtggctttc atgggcaggg aatctcagag atagcaaatg   3900

ccacctgacc agaagtcttt gttatatgga tgggaaccct aacttagggc ttgggcaggg   3960

gaaagagaaa gaagatgaga gattatactt catgagtctt agcaatatgg gagcaggttt   4020

tcactgaatt ctgagggtgc ctctgcatgt cctccaaggc aaagtttggc aaactgtggc   4080

ccccccactg tcatattttg ttaataaaat tttattggaa cacaatcaca              4130


<210>  6759
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6759

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6760
<211>  4015
<212>  DNA
<213>  Homo sapiens

<400>  6760
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gatttgtttt cttctcaaag   1080

tgcgagtaac ttaaaaggtg catctctgct gcctggcaag ctccccacgt cggtttccct   1140

gtttgatgat gaagatgaag aggataatct ttttgggggt acagctgcta agaagcagac   1200

attgtctcta caagctcaga gagaagagaa agcaaaagcc tccgagctct ccaaaaagaa   1260

agcatctgcc ctgttgttca gcagtgatga ggaggaccag tggaatattc ctgcttcaca   1320

gacccactta gcatctgaca gcaggtctaa aggagaaccc agggattctg ggaccctcca   1380

gagccaggag gccaaggctg tgaaaaagac cagtctcttt gaggaagaca aagaagatga   1440

tctttttgcc attgccaagg acagccaaaa gaagacccag agagtgtcac tcctctttga   1500

agacgatgtt gatagcggag gctctctgtt tggctctcct cccacatctg ttcctcctgc   1560

aacaaagaaa aaagagactg tctctgaggc accacctttg ctgttcagcg atgaagaaga   1620

gaaggaggca caacttggag tgaagtctgt ggataagaag gttgagagtg ccaaggagtc   1680

attaaaattt gggagaactg atgtggctga gtcagaaaag gaaggacttt tgactagatc   1740

tgctcaggaa acagtcaagc attctgattt attttcttca tcatccccat gggacaaagg   1800

aaccaagcct agaaccaaaa ctgttcttag cttgtttgat gaggaagagg ataaaatgga   1860

agatcaaaac attatccagg ctccacagaa agaagtagga aagggctgcg atcctgatgc   1920

ccaccccaag agcacaggtg tcttccagga tgaagagctg cttttcagcc acaagctcca   1980

aaaggacaat gacccagatg ttgacctttt tgctggcacc aaaaaaacca agctgttaga   2040

gccaagtgtt gggagcctgt ttggggatga tgaagatgat gatcttttca gctctgccaa   2100

gtcccagcct ttggtacaag agaaaaagag agtagtgaaa aaagaccact ctgttaactc   2160

tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt aaagaaaaag gcatatggaa   2220

gccggaaaca cctcaggact catcaggtct cgctccattt aaaaccaaag aaccatccac   2280

tcggatcggg aagatacaag caaatttagc gatcaaccca gcggccttgc tgcccacagc   2340

ggcttcccag atctctgaag taaagcctgt tttgccagaa ttggcttttc cttcatctga   2400

acacagaagg agccacggtc tggaaagtgt gcctgtcctt cccgggagtg gggaggccgg   2460

tgtgagtttt gatcttccag ctcaggcaga caccttacac agtgcaaaca agagccgtgt   2520

caagatgaga gggaagcgta gaccgcagac ccgtgcagct aggcggctgg ctgctcagga   2580

gtccagcgag gctgaggaca tgagcgtccc cagaggaccc attgcacagt gggctgatgg   2640

cgccatttcc ccaaatggcc atcggccaca gctcagagca gccagtggag aagacagcac   2700

tgaggaggcc ctggcagctg ccgctgcacc ttgggaaggt ggtcctgtgc ctggagtgga   2760

cacaagcccc tttgcaaagt ctctgggtca ttccagaggg gaggctgacc tttttgattc   2820

tggggacatt ttttccacgg gcactggatc tcagtccgtg gagagaacaa aacccaaggc   2880

aaagatagca gagaatcctg ccaacccacc agtgggtggt aaagcaaaga gccccatgtt   2940

tcctgctcta ggcgaggcca gcagtgatga tgatctcttt cagtctgcta aaccaaaacc   3000

agcaaagaaa acaaatccct ttcctctcct ggaagatgag gatgacctct ttacagatca   3060

gaaagtcaag aagaatgaga caaaatccag tagtcagcag gatgtcatat taacaacaca   3120

agatattttt gaggatgata tatttgctac ggaagcaatt aaaccctctc agaaaaccag   3180

agagaaggag aaaacattgg aatctaattt atttgatgat aacattgata tctttgctga   3240

cttaactgta aaaccaaaag aaaagtccaa aaagaaagtg gaagccaagt ctatatttga   3300

tgatgatatg gatgacatct tctccactgg tatccaggct aagacaacca aaccaaaaag   3360

ccgatctgca caggccgcac ctgaaccaag atttgaacac aaggtgtcca acatctttga   3420

tgatcccctg aatgcctttg gaggccagta gagcacacag ggtatccaca tgttaccctg   3480

cagctacatt gttgagttag tgatgatatt gtatatgctc atggtcttaa ctggattaca   3540

aaaagcaaat actagaacag ctagctcatc ttttacccaa tgtacttagt atttttctgc   3600

actggtttaa tcatgcttaa tactacaaaa caaaaataaa tatttcacag tggttggttt   3660

gttttgtttt taaaccacag tttgatttag ttagccttgc tggggccata atatgcttca   3720

gggtgtgtaa aagaagaaat ctctttgtgg ctttcatggg cagggaatct cagagatagc   3780

aaatgccacc tgaccagaag tctttgttat atggatggga accctaactt agggcttggg   3840

caggggaaag agaaagaaga tgagagatta tacttcatga gtcttagcaa tatgggagca   3900

ggttttcact gaattctgag ggtgcctctg catgtcctcc aaggcaaagt ttggcaaact   3960

gtggcccccc cactgtcata ttttgttaat aaaattttat tggaacacaa tcaca        4015


<210>  6761
<211>  531
<212>  PRT
<213>  Homo sapiens

<400>  6761

Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys 
1               5                   10                  15


Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp 
            20                  25                  30


Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp 
        35                  40                  45


Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser 
    50                  55                  60


Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser 
65                  70                  75                  80


Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys 
                85                  90                  95


Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile 
            100                 105                 110


Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp 
        115                 120                 125


Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile 
    130                 135                 140


Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro 
145                 150                 155                 160


Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu 
                165                 170                 175


Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val 
            180                 185                 190


Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro 
        195                 200                 205


Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met 
    210                 215                 220


Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala 
225                 230                 235                 240


Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile 
                245                 250                 255


Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln 
            260                 265                 270


Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala 
        275                 280                 285


Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser 
    290                 295                 300


Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe 
305                 310                 315                 320


Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu 
                325                 330                 335


Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro 
            340                 345                 350


Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala 
        355                 360                 365


Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys 
    370                 375                 380


Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr 
385                 390                 395                 400


Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp 
                405                 410                 415


Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr 
            420                 425                 430


Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu 
        435                 440                 445


Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr 
    450                 455                 460


Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile 
465                 470                 475                 480


Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys 
                485                 490                 495


Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg 
            500                 505                 510


Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe 
        515                 520                 525


Gly Gly Gln 
    530


<210>  6762
<211>  4154
<212>  DNA
<213>  Homo sapiens

<400>  6762
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

ggaccagtgg aatattcctg cttcacagac ccacttagca tctgacagca ggtctaaagg   1440

agaacccagg gattctggga ccctccagag ccaggaggcc aaggctgtga aaaagaccag   1500

tctctttgag gaagacaaag aagatgatct ttttgccatt gccaaggaca gatacatcct   1560

acctcctatt gttcccgaag ttgtctgtca agttttgtgt atggaaagta attcatacct   1620

tcatcagatc tcaaaagaag ctttacacac acaagaagaa gttgagccaa aagaagaccc   1680

agagagtgtc actcctcttt gaagacgatg ttgatagcgg aggctctctg tttggctctc   1740

ctcccacatc tgttcctcct gcaacaaaga aaaaagagac tgtctctgag gcaccacctt   1800

tgctgttcag cgatgaagaa gagaaggagg cacaacttgg agtgaagtct gtggataaga   1860

aggttgagag tgccaaggag tcattaaaat ttgggagaac tgatgtggct gagtcagaaa   1920

aggaaggact tttgactaga tctgctcagg aaacagtcaa gcattctgat ttattttctt   1980

catcatcccc atgggacaaa ggaaccaagc ctagaaccaa aactgttctt agcttgtttg   2040

atgaggaaga ggataaaatg gaagatcaaa acattatcca ggctccacag aaagaagtag   2100

gaaagggctg cgatcctgat gcccacccca agagcacagg tgtcttccag gatgaagagc   2160

tgcttttcag ccacaagctc caaaaggaca atgacccaga tgttgacctt tttgctggca   2220

ccaaaaaaac caagctgtta gagccaagtg ttgggagcct gtttggggat gatgaagatg   2280

atgatctttt cagctctgcc aagtcccagc ctttggtaca agagaaaaag agagtagtga   2340

aaaaagacca ctctgttaac tctttcaaaa accagaaaca tcctgaatcc attcaaggta   2400

gtaaagaaaa aggcatatgg aagccggaaa cacctcaggc aaatttagcg atcaacccag   2460

cggccttgct gcccacagcg gcttcccaga tctctgaagt aaagcctgtt ttgccagaat   2520

tggcttttcc ttcatctgaa cacagaagga gccacggtct ggaaagtgtg cctgtccttc   2580

ccgggagtgg ggaggccggt gtgagttttg atcttccagc tcaggcagac accttacaca   2640

gtgcaaacaa gagccgtgtc aagatgagag ggaagcgtag accgcagacc cgtgcagcta   2700

ggcggctggc tgctcaggag tccagcgagg ctgaggacat gagcgtcccc agaggaccca   2760

ttgcacagtg ggctgatggc gccatttccc caaatggcca tcggccacag ctcagagcag   2820

ccagtggaga agacagcact gaggaggccc tggcagctgc cgctgcacct tgggaaggtg   2880

gtcctgtgcc tggagtggac acaagcccct ttgcaaagtc tctgggtcat tccagagggg   2940

aggctgacct ttttgattct ggggacattt tttccacggg cactggatct cagtccgtgg   3000

agagaacaaa acccaaggca aagatagcag agaatcctgc caacccacca gtgggtggta   3060

aagcaaagag ccccatgttt cctgctctag gcgaggccag cagtgatgat gatctctttc   3120

agtctgctaa accaaaacca gcaaagaaaa caaatccctt tcctctcctg gaagatgagg   3180

atgacctctt tacagatcag aaagtcaaga agaatgagac aaaatccagt agtcagcagg   3240

atgtcatatt aacaacacaa gatatttttg aggatgatat atttgctacg gaagcaatta   3300

aaccctctca gaaaaccaga gagaaggaga aaacattgga atctaattta tttgatgata   3360

acattgatat ctttgctgac ttaactgtaa aaccaaaaga aaagtccaaa aagaaagtgg   3420

aagccaagtc tatatttgat gatgatatgg atgacatctt ctccactggt atccaggcta   3480

agacaaccaa accaaaaagc cgatctgcac aggccgcacc tgaaccaaga tttgaacaca   3540

aggtgtccaa catctttgat gatcccctga atgcctttgg aggccagtag agcacacagg   3600

gtatccacat gttaccctgc agctacattg ttgagttagt gatgatattg tatatgctca   3660

tggtcttaac tggattacaa aaagcaaata ctagaacagc tagctcatct tttacccaat   3720

gtacttagta tttttctgca ctggtttaat catgcttaat actacaaaac aaaaataaat   3780

atttcacagt ggttggtttg ttttgttttt aaaccacagt ttgatttagt tagccttgct   3840

ggggccataa tatgcttcag ggtgtgtaaa agaagaaatc tctttgtggc tttcatgggc   3900

agggaatctc agagatagca aatgccacct gaccagaagt ctttgttata tggatgggaa   3960

ccctaactta gggcttgggc aggggaaaga gaaagaagat gagagattat acttcatgag   4020

tcttagcaat atgggagcag gttttcactg aattctgagg gtgcctctgc atgtcctcca   4080

aggcaaagtt tggcaaactg tggccccccc actgtcatat tttgttaata aaattttatt   4140

ggaacacaat caca                                                     4154


<210>  6763
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6763

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6764
<211>  4039
<212>  DNA
<213>  Homo sapiens

<400>  6764
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

ggaccagtgg aatattcctg cttcacagac ccacttagca tctgacagca ggtctaaagg   1440

agaacccagg gattctggga ccctccagag ccaggaggcc aaggctgtga aaaagaccag   1500

tctctttgag gaagacaaag aagatgatct ttttgccatt gccaaggaca gccaaaagaa   1560

gacccagaga gtgtcactcc tctttgaaga cgatgttgat agcggaggct ctctgtttgg   1620

ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa gagactgtct ctgaggcacc   1680

acctttgctg ttcagcgatg aagaagagaa ggaggcacaa cttggagtga agtctgtgga   1740

taagaaggtt gagagtgcca aggagtcatt aaaatttggg agaactgatg tggctgagtc   1800

agaaaaggaa ggacttttga ctagatctgc tcaggaaaca gtcaagcatt ctgatttatt   1860

ttcttcatca tccccatggg acaaaggaac caagcctaga accaaaactg ttcttagctt   1920

gtttgatgag gaagaggata aaatggaaga tcaaaacatt atccaggctc cacagaaaga   1980

agtaggaaag ggctgcgatc ctgatgccca ccccaagagc acaggtgtct tccaggatga   2040

agagctgctt ttcagccaca agctccaaaa ggacaatgac ccagatgttg acctttttgc   2100

tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg agcctgtttg gggatgatga   2160

agatgatgat cttttcagct ctgccaagtc ccagcctttg gtacaagaga aaaagagagt   2220

agtgaaaaaa gaccactctg ttaactcttt caaaaaccag aaacatcctg aatccattca   2280

aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct caggcaaatt tagcgatcaa   2340

cccagcggcc ttgctgccca cagcggcttc ccagatctct gaagtaaagc ctgttttgcc   2400

agaattggct tttccttcat ctgaacacag aaggagccac ggtctggaaa gtgtgcctgt   2460

ccttcccggg agtggggagg ccggtgtgag ttttgatctt ccagctcagg cagacacctt   2520

acacagtgca aacaagagcc gtgtcaagat gagagggaag cgtagaccgc agacccgtgc   2580

agctaggcgg ctggctgctc aggagtccag cgaggctgag gacatgagcg tccccagagg   2640

acccattgca cagtgggctg atggcgccat ttccccaaat ggccatcggc cacagctcag   2700

agcagccagt ggagaagaca gcactgagga ggccctggca gctgccgctg caccttggga   2760

aggtggtcct gtgcctggag tggacacaag cccctttgca aagtctctgg gtcattccag   2820

aggggaggct gacctttttg attctgggga cattttttcc acgggcactg gatctcagtc   2880

cgtggagaga acaaaaccca aggcaaagat agcagagaat cctgccaacc caccagtggg   2940

tggtaaagca aagagcccca tgtttcctgc tctaggcgag gccagcagtg atgatgatct   3000

ctttcagtct gctaaaccaa aaccagcaaa gaaaacaaat ccctttcctc tcctggaaga   3060

tgaggatgac ctctttacag atcagaaagt caagaagaat gagacaaaat ccagtagtca   3120

gcaggatgtc atattaacaa cacaagatat ttttgaggat gatatatttg ctacggaagc   3180

aattaaaccc tctcagaaaa ccagagagaa ggagaaaaca ttggaatcta atttatttga   3240

tgataacatt gatatctttg ctgacttaac tgtaaaacca aaagaaaagt ccaaaaagaa   3300

agtggaagcc aagtctatat ttgatgatga tatggatgac atcttctcca ctggtatcca   3360

ggctaagaca accaaaccaa aaagccgatc tgcacaggcc gcacctgaac caagatttga   3420

acacaaggtg tccaacatct ttgatgatcc cctgaatgcc tttggaggcc agtagagcac   3480

acagggtatc cacatgttac cctgcagcta cattgttgag ttagtgatga tattgtatat   3540

gctcatggtc ttaactggat tacaaaaagc aaatactaga acagctagct catcttttac   3600

ccaatgtact tagtattttt ctgcactggt ttaatcatgc ttaatactac aaaacaaaaa   3660

taaatatttc acagtggttg gtttgttttg tttttaaacc acagtttgat ttagttagcc   3720

ttgctggggc cataatatgc ttcagggtgt gtaaaagaag aaatctcttt gtggctttca   3780

tgggcaggga atctcagaga tagcaaatgc cacctgacca gaagtctttg ttatatggat   3840

gggaacccta acttagggct tgggcagggg aaagagaaag aagatgagag attatacttc   3900

atgagtctta gcaatatggg agcaggtttt cactgaattc tgagggtgcc tctgcatgtc   3960

ctccaaggca aagtttggca aactgtggcc cccccactgt catattttgt taataaaatt   4020

ttattggaac acaatcaca                                                4039


<210>  6765
<211>  510
<212>  PRT
<213>  Homo sapiens

<400>  6765

Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys 
1               5                   10                  15


Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp 
            20                  25                  30


Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp 
        35                  40                  45


Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser 
    50                  55                  60


Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser 
65                  70                  75                  80


Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys 
                85                  90                  95


Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile 
            100                 105                 110


Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala 
        115                 120                 125


Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln 
    130                 135                 140


Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser 
145                 150                 155                 160


Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly 
                165                 170                 175


Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr 
            180                 185                 190


Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg 
        195                 200                 205


Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu 
    210                 215                 220


Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp 
225                 230                 235                 240


Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser 
                245                 250                 255


Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp 
            260                 265                 270


Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser 
        275                 280                 285


Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile 
    290                 295                 300


Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys 
305                 310                 315                 320


Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala 
                325                 330                 335


Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp 
            340                 345                 350


Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe 
        355                 360                 365


Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys 
    370                 375                 380


Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr 
385                 390                 395                 400


Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro 
                405                 410                 415


Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe 
            420                 425                 430


Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu 
        435                 440                 445


Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met 
    450                 455                 460


Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys 
465                 470                 475                 480


Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val 
                485                 490                 495


Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            500                 505                 510


<210>  6766
<211>  4102
<212>  DNA
<213>  Homo sapiens

<400>  6766
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

ggaccagtgg aatattcctg cttcacagac ccacttagca tctgacagca ggtctaaagg   1440

agaacccagg gattctggga ccctccagag ccaggaggcc aaggctgtga aaaagaccag   1500

tctctttgag gaagacaaag aagatgatct ttttgccatt gccaaggaca gccaaaagaa   1560

gacccagaga gtgtcactcc tctttgaaga cgatgttgat agcggaggct ctctgtttgg   1620

ctctcctccc acatctgttc ctcctgcaac aaagaaaaaa gagactgtct ctgaggcacc   1680

acctttgctg ttcagcgatg aagaagagaa ggaggcacaa cttggagtga agtctgtgga   1740

taagaaggtt gagagtgcca aggagtcatt aaaatttggg agaactgatg tggctgagtc   1800

agaaaaggaa ggacttttga ctagatctgc tcaggaaaca gtcaagcatt ctgatttatt   1860

ttcttcatca tccccatggg acaaaggaac caagcctaga accaaaactg ttcttagctt   1920

gtttgatgag gaagaggata aaatggaaga tcaaaacatt atccaggctc cacagaaaga   1980

agtaggaaag ggctgcgatc ctgatgccca ccccaagagc acaggtgtct tccaggatga   2040

agagctgctt ttcagccaca agctccaaaa ggacaatgac ccagatgttg acctttttgc   2100

tggcaccaaa aaaaccaagc tgttagagcc aagtgttggg agcctgtttg gggatgatga   2160

agatgatgat cttttcagct ctgccaagtc ccagcctttg gtacaagaga aaaagagagt   2220

agtgaaaaaa gaccactctg ttaactcttt caaaaaccag aaacatcctg aatccattca   2280

aggtagtaaa gaaaaaggca tatggaagcc ggaaacacct caggactcat caggtctcgc   2340

tccatttaaa accaaagaac catccactcg gatcgggaag atacaagcaa atttagcgat   2400

caacccagcg gccttgctgc ccacagcggc ttcccagatc tctgaagtaa agcctgtttt   2460

gccagaattg gcttttcctt catctgaaca cagaaggagc cacggtctgg aaagtgtgcc   2520

tgtccttccc gggagtgggg aggccggtgt gagttttgat cttccagctc aggcagacac   2580

cttacacagt gcaaacaaga gccgtgtcaa gatgagaggg aagcgtagac cgcagacccg   2640

tgcagctagg cggctggctg ctcaggagtc cagcgaggct gaggacatga gcgtccccag   2700

aggacccatt gcacagtggg ctgatggcgc catttcccca aatggccatc ggccacagct   2760

cagagcagcc agtggagaag acagcactga ggaggccctg gcagctgccg ctgcaccttg   2820

ggaaggtggt cctgtgcctg gagtggacac aagccccttt gcaaagtctc tgggtcattc   2880

cagaggggag gctgaccttt ttgattctgg ggacattttt tccacgggca ctggatctca   2940

gtccgtggag agaacaaaac ccaaggcaaa gatagcagag aatcctgcca acccaccagt   3000

gggtggtaaa gcaaagagcc ccatgtttcc tgctctaggc gaggccagca gtgatgatga   3060

tctctttcag tctgctaaac caaaaccagc aaagaaaaca aatccctttc ctctcctgga   3120

agatgaggat gacctcttta cagatcagaa agtcaagaag aatgagacaa aatccagtag   3180

tcagcaggat gtcatattaa caacacaaga tatttttgag gatgatatat ttgctacgga   3240

agcaattaaa ccctctcaga aaaccagaga gaaggagaaa acattggaat ctaatttatt   3300

tgatgataac attgatatct ttgctgactt aactgtaaaa ccaaaagaaa agtccaaaaa   3360

gaaagtggaa gccaagtcta tatttgatga tgatatggat gacatcttct ccactggtat   3420

ccaggctaag acaaccaaac caaaaagccg atctgcacag gccgcacctg aaccaagatt   3480

tgaacacaag gtgtccaaca tctttgatga tcccctgaat gcctttggag gccagtagag   3540

cacacagggt atccacatgt taccctgcag ctacattgtt gagttagtga tgatattgta   3600

tatgctcatg gtcttaactg gattacaaaa agcaaatact agaacagcta gctcatcttt   3660

tacccaatgt acttagtatt tttctgcact ggtttaatca tgcttaatac tacaaaacaa   3720

aaataaatat ttcacagtgg ttggtttgtt ttgtttttaa accacagttt gatttagtta   3780

gccttgctgg ggccataata tgcttcaggg tgtgtaaaag aagaaatctc tttgtggctt   3840

tcatgggcag ggaatctcag agatagcaaa tgccacctga ccagaagtct ttgttatatg   3900

gatgggaacc ctaacttagg gcttgggcag gggaaagaga aagaagatga gagattatac   3960

ttcatgagtc ttagcaatat gggagcaggt tttcactgaa ttctgagggt gcctctgcat   4020

gtcctccaag gcaaagtttg gcaaactgtg gcccccccac tgtcatattt tgttaataaa   4080

attttattgg aacacaatca ca                                            4102


<210>  6767
<211>  531
<212>  PRT
<213>  Homo sapiens

<400>  6767

Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys 
1               5                   10                  15


Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp 
            20                  25                  30


Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp 
        35                  40                  45


Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser 
    50                  55                  60


Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser 
65                  70                  75                  80


Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys 
                85                  90                  95


Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile 
            100                 105                 110


Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Asp 
        115                 120                 125


Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr Arg Ile 
    130                 135                 140


Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro 
145                 150                 155                 160


Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu 
                165                 170                 175


Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val 
            180                 185                 190


Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro 
        195                 200                 205


Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met 
    210                 215                 220


Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala 
225                 230                 235                 240


Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile 
                245                 250                 255


Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln 
            260                 265                 270


Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala 
        275                 280                 285


Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser 
    290                 295                 300


Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe 
305                 310                 315                 320


Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu 
                325                 330                 335


Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro 
            340                 345                 350


Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala 
        355                 360                 365


Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys 
    370                 375                 380


Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr 
385                 390                 395                 400


Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp 
                405                 410                 415


Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr 
            420                 425                 430


Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu 
        435                 440                 445


Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr 
    450                 455                 460


Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile 
465                 470                 475                 480


Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys 
                485                 490                 495


Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg 
            500                 505                 510


Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe 
        515                 520                 525


Gly Gly Gln 
    530


<210>  6768
<211>  4217
<212>  DNA
<213>  Homo sapiens

<400>  6768
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

ggaccagtgg aatattcctg cttcacagac ccacttagca tctgacagca ggtctaaagg   1440

agaacccagg gattctggga ccctccagag ccaggaggcc aaggctgtga aaaagaccag   1500

tctctttgag gaagacaaag aagatgatct ttttgccatt gccaaggaca gatacatcct   1560

acctcctatt gttcccgaag ttgtctgtca agttttgtgt atggaaagta attcatacct   1620

tcatcagatc tcaaaagaag ctttacacac acaagaagaa gttgagccaa aagaagaccc   1680

agagagtgtc actcctcttt gaagacgatg ttgatagcgg aggctctctg tttggctctc   1740

ctcccacatc tgttcctcct gcaacaaaga aaaaagagac tgtctctgag gcaccacctt   1800

tgctgttcag cgatgaagaa gagaaggagg cacaacttgg agtgaagtct gtggataaga   1860

aggttgagag tgccaaggag tcattaaaat ttgggagaac tgatgtggct gagtcagaaa   1920

aggaaggact tttgactaga tctgctcagg aaacagtcaa gcattctgat ttattttctt   1980

catcatcccc atgggacaaa ggaaccaagc ctagaaccaa aactgttctt agcttgtttg   2040

atgaggaaga ggataaaatg gaagatcaaa acattatcca ggctccacag aaagaagtag   2100

gaaagggctg cgatcctgat gcccacccca agagcacagg tgtcttccag gatgaagagc   2160

tgcttttcag ccacaagctc caaaaggaca atgacccaga tgttgacctt tttgctggca   2220

ccaaaaaaac caagctgtta gagccaagtg ttgggagcct gtttggggat gatgaagatg   2280

atgatctttt cagctctgcc aagtcccagc ctttggtaca agagaaaaag agagtagtga   2340

aaaaagacca ctctgttaac tctttcaaaa accagaaaca tcctgaatcc attcaaggta   2400

gtaaagaaaa aggcatatgg aagccggaaa cacctcagga ctcatcaggt ctcgctccat   2460

ttaaaaccaa agaaccatcc actcggatcg ggaagataca agcaaattta gcgatcaacc   2520

cagcggcctt gctgcccaca gcggcttccc agatctctga agtaaagcct gttttgccag   2580

aattggcttt tccttcatct gaacacagaa ggagccacgg tctggaaagt gtgcctgtcc   2640

ttcccgggag tggggaggcc ggtgtgagtt ttgatcttcc agctcaggca gacaccttac   2700

acagtgcaaa caagagccgt gtcaagatga gagggaagcg tagaccgcag acccgtgcag   2760

ctaggcggct ggctgctcag gagtccagcg aggctgagga catgagcgtc cccagaggac   2820

ccattgcaca gtgggctgat ggcgccattt ccccaaatgg ccatcggcca cagctcagag   2880

cagccagtgg agaagacagc actgaggagg ccctggcagc tgccgctgca ccttgggaag   2940

gtggtcctgt gcctggagtg gacacaagcc cctttgcaaa gtctctgggt cattccagag   3000

gggaggctga cctttttgat tctggggaca ttttttccac gggcactgga tctcagtccg   3060

tggagagaac aaaacccaag gcaaagatag cagagaatcc tgccaaccca ccagtgggtg   3120

gtaaagcaaa gagccccatg tttcctgctc taggcgaggc cagcagtgat gatgatctct   3180

ttcagtctgc taaaccaaaa ccagcaaaga aaacaaatcc ctttcctctc ctggaagatg   3240

aggatgacct ctttacagat cagaaagtca agaagaatga gacaaaatcc agtagtcagc   3300

aggatgtcat attaacaaca caagatattt ttgaggatga tatatttgct acggaagcaa   3360

ttaaaccctc tcagaaaacc agagagaagg agaaaacatt ggaatctaat ttatttgatg   3420

ataacattga tatctttgct gacttaactg taaaaccaaa agaaaagtcc aaaaagaaag   3480

tggaagccaa gtctatattt gatgatgata tggatgacat cttctccact ggtatccagg   3540

ctaagacaac caaaccaaaa agccgatctg cacaggccgc acctgaacca agatttgaac   3600

acaaggtgtc caacatcttt gatgatcccc tgaatgcctt tggaggccag tagagcacac   3660

agggtatcca catgttaccc tgcagctaca ttgttgagtt agtgatgata ttgtatatgc   3720

tcatggtctt aactggatta caaaaagcaa atactagaac agctagctca tcttttaccc   3780

aatgtactta gtatttttct gcactggttt aatcatgctt aatactacaa aacaaaaata   3840

aatatttcac agtggttggt ttgttttgtt tttaaaccac agtttgattt agttagcctt   3900

gctggggcca taatatgctt cagggtgtgt aaaagaagaa atctctttgt ggctttcatg   3960

ggcagggaat ctcagagata gcaaatgcca cctgaccaga agtctttgtt atatggatgg   4020

gaaccctaac ttagggcttg ggcaggggaa agagaaagaa gatgagagat tatacttcat   4080

gagtcttagc aatatgggag caggttttca ctgaattctg agggtgcctc tgcatgtcct   4140

ccaaggcaaa gtttggcaaa ctgtggcccc cccactgtca tattttgtta ataaaatttt   4200

attggaacac aatcaca                                                  4217


<210>  6769
<211>  709
<212>  PRT
<213>  Homo sapiens

<400>  6769

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Asp Ser Ser Gly Leu Ala Pro Phe Lys Thr Lys Glu Pro Ser Thr 
305                 310                 315                 320


Arg Ile Gly Lys Ile Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu 
                325                 330                 335


Leu Pro Thr Ala Ala Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro 
            340                 345                 350


Glu Leu Ala Phe Pro Ser Ser Glu His Arg Arg Ser His Gly Leu Glu 
        355                 360                 365


Ser Val Pro Val Leu Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp 
    370                 375                 380


Leu Pro Ala Gln Ala Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val 
385                 390                 395                 400


Lys Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu 
                405                 410                 415


Ala Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly 
            420                 425                 430


Pro Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg 
        435                 440                 445


Pro Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu 
    450                 455                 460


Ala Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp 
465                 470                 475                 480


Thr Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp 
                485                 490                 495


Leu Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser 
            500                 505                 510


Val Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn 
        515                 520                 525


Pro Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly 
    530                 535                 540


Glu Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro 
545                 550                 555                 560


Ala Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu 
                565                 570                 575


Phe Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln 
            580                 585                 590


Gln Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe 
        595                 600                 605


Ala Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys 
    610                 615                 620


Thr Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp 
625                 630                 635                 640


Leu Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys 
                645                 650                 655


Ser Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln 
            660                 665                 670


Ala Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu 
        675                 680                 685


Pro Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn 
    690                 695                 700


Ala Phe Gly Gly Gln 
705


<210>  6770
<211>  3716
<212>  DNA
<213>  Homo sapiens

<400>  6770
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gttaccttat cttacagcaa   1080

aaatctcaag ccctcatcag aaacaaagac tcaaaaaggc ttattttcag atgaggagga   1140

ctctgaggat ttgttttctt ctcaaagtgc gagtaactta aaaggtgcat ctctgctgcc   1200

tggcaagctc cccacgtcgg tttccctgtt tgatgatgaa gatgaagagg ataatctttt   1260

tgggggtaca gctgctaaga agcagacatt gtctctacaa gctcagagag aagagaaagc   1320

aaaagcctcc gagctctcca aaaagaaagc atctgccctg ttgttcagca gtgatgagga   1380

gccaaaagaa gacccagaga gtgtcactcc tctttgaaga cgatgttgat agcggaggct   1440

ctctgtttgg ctctcctccc acatctgttc ctcctgcaac aaaggaagga cttttgacta   1500

gatctgctca ggaaacagtc aagcattctg atttattttc ttcatcatcc ccatgggaca   1560

aaggaaccaa gcctagaacc aaaactgttc ttagcttgtt tgatgaggaa gaggataaaa   1620

tggaagatca aaacattatc caggctccac agaaagaagt aggaaagggc tgcgatcctg   1680

atgcccaccc caagagcaca ggtgtcttcc aggatgaaga gctgcttttc agccacaagc   1740

tccaaaagga caatgaccca gatgttgacc tttttgctgg caccaaaaaa accaagctgt   1800

tagagccaag tgttgggagc ctgtttgggg atgatgaaga tgatgatctt ttcagctctg   1860

ccaagtccca gcctttggta caagagaaaa agagagtagt gaaaaaagac cactctgtta   1920

actctttcaa aaaccagaaa catcctgaat ccattcaagg tagtaaagaa aaaggcatat   1980

ggaagccgga aacacctcag gcaaatttag cgatcaaccc agcggccttg ctgcccacag   2040

cggcttccca gatctctgaa gtaaagcctg ttttgccaga attggctttt ccttcatctg   2100

aacacagaag gagccacggt ctggaaagtg tgcctgtcct tcccgggagt ggggaggccg   2160

gtgtgagttt tgatcttcca gctcaggcag acaccttaca cagtgcaaac aagagccgtg   2220

tcaagatgag agggaagcgt agaccgcaga cccgtgcagc taggcggctg gctgctcagg   2280

agtccagcga ggctgaggac atgagcgtcc ccagaggacc cattgcacag tgggctgatg   2340

gcgccatttc cccaaatggc catcggccac agctcagagc agccagtgga gaagacagca   2400

ctgaggaggc cctggcagct gccgctgcac cttgggaagg tggtcctgtg cctggagtgg   2460

acacaagccc ctttgcaaag tctctgggtc attccagagg ggaggctgac ctttttgatt   2520

ctggggacat tttttccacg ggcactggat ctcagtccgt ggagagaaca aaacccaagg   2580

caaagatagc agagaatcct gccaacccac cagtgggtgg taaagcaaag agccccatgt   2640

ttcctgctct aggcgaggcc agcagtgatg atgatctctt tcagtctgct aaaccaaaac   2700

cagcaaagaa aacaaatccc tttcctctcc tggaagatga ggatgacctc tttacagatc   2760

agaaagtcaa gaagaatgag acaaaatcca gtagtcagca ggatgtcata ttaacaacac   2820

aagatatttt tgaggatgat atatttgcta cggaagcaat taaaccctct cagaaaacca   2880

gagagaagga gaaaacattg gaatctaatt tatttgatga taacattgat atctttgctg   2940

acttaactgt aaaaccaaaa gaaaagtcca aaaagaaagt ggaagccaag tctatatttg   3000

atgatgatat ggatgacatc ttctccactg gtatccaggc taagacaacc aaaccaaaaa   3060

gccgatctgc acaggccgca cctgaaccaa gatttgaaca caaggtgtcc aacatctttg   3120

atgatcccct gaatgccttt ggaggccagt agagcacaca gggtatccac atgttaccct   3180

gcagctacat tgttgagtta gtgatgatat tgtatatgct catggtctta actggattac   3240

aaaaagcaaa tactagaaca gctagctcat cttttaccca atgtacttag tatttttctg   3300

cactggttta atcatgctta atactacaaa acaaaaataa atatttcaca gtggttggtt   3360

tgttttgttt ttaaaccaca gtttgattta gttagccttg ctggggccat aatatgcttc   3420

agggtgtgta aaagaagaaa tctctttgtg gctttcatgg gcagggaatc tcagagatag   3480

caaatgccac ctgaccagaa gtctttgtta tatggatggg aaccctaact tagggcttgg   3540

gcaggggaaa gagaaagaag atgagagatt atacttcatg agtcttagca atatgggagc   3600

aggttttcac tgaattctga gggtgcctct gcatgtcctc caaggcaaag tttggcaaac   3660

tgtggccccc ccactgtcat attttgttaa taaaatttta ttggaacaca atcaca       3716


<210>  6771
<211>  639
<212>  PRT
<213>  Homo sapiens

<400>  6771

Met Met Lys Met Lys Arg Ile Ile Phe Leu Gly Val Gln Leu Leu Arg 
1               5                   10                  15


Ser Arg His Cys Leu Tyr Lys Leu Arg Glu Lys Arg Lys Gln Lys Pro 
            20                  25                  30


Pro Ser Ser Pro Lys Arg Lys His Leu Pro Cys Cys Ser Ala Val Met 
        35                  40                  45


Arg Ser Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp 
    50                  55                  60


Val Asp Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro 
65                  70                  75                  80


Pro Ala Thr Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr Val 
                85                  90                  95


Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly Thr 
            100                 105                 110


Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu Asp 
        115                 120                 125


Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly 
    130                 135                 140


Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln 
145                 150                 155                 160


Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro 
                165                 170                 175


Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro 
            180                 185                 190


Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser 
        195                 200                 205


Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys 
    210                 215                 220


Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser 
225                 230                 235                 240


Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln 
                245                 250                 255


Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser 
            260                 265                 270


Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser 
        275                 280                 285


Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro 
    290                 295                 300


Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp 
305                 310                 315                 320


Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg 
                325                 330                 335


Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser 
            340                 345                 350


Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala 
        355                 360                 365


Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala 
    370                 375                 380


Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro 
385                 390                 395                 400


Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys 
                405                 410                 415


Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp 
            420                 425                 430


Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro 
        435                 440                 445


Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys 
    450                 455                 460


Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp 
465                 470                 475                 480


Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro 
                485                 490                 495


Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val 
            500                 505                 510


Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr 
        515                 520                 525


Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys 
    530                 535                 540


Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu 
545                 550                 555                 560


Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys 
                565                 570                 575


Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp 
            580                 585                 590


Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro 
        595                 600                 605


Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys 
    610                 615                 620


Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
625                 630                 635


<210>  6772
<211>  3952
<212>  DNA
<213>  Homo sapiens

<400>  6772
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gatttgtttt cttctcaaag   1080

tgcgagtaac ttaaaaggtg catctctgct gcctggcaag ctccccacgt cggtttccct   1140

gtttgatgat gaagatgaag aggataatct ttttgggggt acagctgcta agaagcagac   1200

attgtctcta caagctcaga gagaagagaa agcaaaagcc tccgagctct ccaaaaagaa   1260

agcatctgcc ctgttgttca gcagtgatga ggaggaccag tggaatattc ctgcttcaca   1320

gacccactta gcatctgaca gcaggtctaa aggagaaccc agggattctg ggaccctcca   1380

gagccaggag gccaaggctg tgaaaaagac cagtctcttt gaggaagaca aagaagatga   1440

tctttttgcc attgccaagg acagccaaaa gaagacccag agagtgtcac tcctctttga   1500

agacgatgtt gatagcggag gctctctgtt tggctctcct cccacatctg ttcctcctgc   1560

aacaaagaaa aaagagactg tctctgaggc accacctttg ctgttcagcg atgaagaaga   1620

gaaggaggca caacttggag tgaagtctgt ggataagaag gttgagagtg ccaaggagtc   1680

attaaaattt gggagaactg atgtggctga gtcagaaaag gaaggacttt tgactagatc   1740

tgctcaggaa acagtcaagc attctgattt attttcttca tcatccccat gggacaaagg   1800

aaccaagcct agaaccaaaa ctgttcttag cttgtttgat gaggaagagg ataaaatgga   1860

agatcaaaac attatccagg ctccacagaa agaagtagga aagggctgcg atcctgatgc   1920

ccaccccaag agcacaggtg tcttccagga tgaagagctg cttttcagcc acaagctcca   1980

aaaggacaat gacccagatg ttgacctttt tgctggcacc aaaaaaacca agctgttaga   2040

gccaagtgtt gggagcctgt ttggggatga tgaagatgat gatcttttca gctctgccaa   2100

gtcccagcct ttggtacaag agaaaaagag agtagtgaaa aaagaccact ctgttaactc   2160

tttcaaaaac cagaaacatc ctgaatccat tcaaggtagt aaagaaaaag gcatatggaa   2220

gccggaaaca cctcaggcaa atttagcgat caacccagcg gccttgctgc ccacagcggc   2280

ttcccagatc tctgaagtaa agcctgtttt gccagaattg gcttttcctt catctgaaca   2340

cagaaggagc cacggtctgg aaagtgtgcc tgtccttccc gggagtgggg aggccggtgt   2400

gagttttgat cttccagctc aggcagacac cttacacagt gcaaacaaga gccgtgtcaa   2460

gatgagaggg aagcgtagac cgcagacccg tgcagctagg cggctggctg ctcaggagtc   2520

cagcgaggct gaggacatga gcgtccccag aggacccatt gcacagtggg ctgatggcgc   2580

catttcccca aatggccatc ggccacagct cagagcagcc agtggagaag acagcactga   2640

ggaggccctg gcagctgccg ctgcaccttg ggaaggtggt cctgtgcctg gagtggacac   2700

aagccccttt gcaaagtctc tgggtcattc cagaggggag gctgaccttt ttgattctgg   2760

ggacattttt tccacgggca ctggatctca gtccgtggag agaacaaaac ccaaggcaaa   2820

gatagcagag aatcctgcca acccaccagt gggtggtaaa gcaaagagcc ccatgtttcc   2880

tgctctaggc gaggccagca gtgatgatga tctctttcag tctgctaaac caaaaccagc   2940

aaagaaaaca aatccctttc ctctcctgga agatgaggat gacctcttta cagatcagaa   3000

agtcaagaag aatgagacaa aatccagtag tcagcaggat gtcatattaa caacacaaga   3060

tatttttgag gatgatatat ttgctacgga agcaattaaa ccctctcaga aaaccagaga   3120

gaaggagaaa acattggaat ctaatttatt tgatgataac attgatatct ttgctgactt   3180

aactgtaaaa ccaaaagaaa agtccaaaaa gaaagtggaa gccaagtcta tatttgatga   3240

tgatatggat gacatcttct ccactggtat ccaggctaag acaaccaaac caaaaagccg   3300

atctgcacag gccgcacctg aaccaagatt tgaacacaag gtgtccaaca tctttgatga   3360

tcccctgaat gcctttggag gccagtagag cacacagggt atccacatgt taccctgcag   3420

ctacattgtt gagttagtga tgatattgta tatgctcatg gtcttaactg gattacaaaa   3480

agcaaatact agaacagcta gctcatcttt tacccaatgt acttagtatt tttctgcact   3540

ggtttaatca tgcttaatac tacaaaacaa aaataaatat ttcacagtgg ttggtttgtt   3600

ttgtttttaa accacagttt gatttagtta gccttgctgg ggccataata tgcttcaggg   3660

tgtgtaaaag aagaaatctc tttgtggctt tcatgggcag ggaatctcag agatagcaaa   3720

tgccacctga ccagaagtct ttgttatatg gatgggaacc ctaacttagg gcttgggcag   3780

gggaaagaga aagaagatga gagattatac ttcatgagtc ttagcaatat gggagcaggt   3840

tttcactgaa ttctgagggt gcctctgcat gtcctccaag gcaaagtttg gcaaactgtg   3900

gcccccccac tgtcatattt tgttaataaa attttattgg aacacaatca ca           3952


<210>  6773
<211>  510
<212>  PRT
<213>  Homo sapiens

<400>  6773

Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val Gly Lys 
1               5                   10                  15


Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe Gln Asp 
            20                  25                  30


Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp Pro Asp 
        35                  40                  45


Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu Pro Ser 
    50                  55                  60


Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe Ser Ser 
65                  70                  75                  80


Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val Lys Lys 
                85                  90                  95


Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu Ser Ile 
            100                 105                 110


Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro Gln Ala 
        115                 120                 125


Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala Ser Gln 
    130                 135                 140


Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro Ser Ser 
145                 150                 155                 160


Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu Pro Gly 
                165                 170                 175


Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala Asp Thr 
            180                 185                 190


Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys Arg Arg 
        195                 200                 205


Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser Ser Glu 
    210                 215                 220


Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp Ala Asp 
225                 230                 235                 240


Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala Ala Ser 
                245                 250                 255


Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala Pro Trp 
            260                 265                 270


Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala Lys Ser 
        275                 280                 285


Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly Asp Ile 
    290                 295                 300


Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys Pro Lys 
305                 310                 315                 320


Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly Lys Ala 
                325                 330                 335


Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp Asp Asp 
            340                 345                 350


Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn Pro Phe 
        355                 360                 365


Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys Val Lys 
    370                 375                 380


Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu Thr Thr 
385                 390                 395                 400


Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile Lys Pro 
                405                 410                 415


Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn Leu Phe 
            420                 425                 430


Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro Lys Glu 
        435                 440                 445


Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp Asp Met 
    450                 455                 460


Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys Pro Lys 
465                 470                 475                 480


Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His Lys Val 
                485                 490                 495


Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
            500                 505                 510


<210>  6774
<211>  4067
<212>  DNA
<213>  Homo sapiens

<400>  6774
tttacagcaa tcatttcttg tcttcctaga attcttagaa gtatagaaac ttaggaatct     60

caagcatttg ttttcaataa aggatacacc aggccttttc ctgcaaacag ccatgtcgat    120

tacattagac ttgtccctgt gtcagtttgc agatcccttt gtttattctg cccttccttc    180

ccccagattg gttggggaat gggtcttgaa tgtggcgtct gacccgaatg cttgcttcag    240

agtaaatcta gatccagggt gctggcctag agaatgaatg ctgtgtgcca cagacgtgga    300

cagacttgag agtggaggcc cagagagtct tttgagggtg tcagtggact gtgccagggg    360

tttagtgtga aattcatcag actgcctcac actttgttaa atagtgtcag ataaactcca    420

tgccagtttg gagacacagc agatgccaac ccgggaattt gagttctgga cccatcttta    480

atactccctg caaaacattg ctttctgttt gctagatgaa gaggataact tattcgcacc    540

ccccaagctg accgacgagg acttctcgcc atttggctct ggaggtggcc tgttcagtgg    600

cggcaagggg ctatttgatg atgaggacga ggagagtgac ctcttcacgg aagcctccca    660

ggatcggcaa gctggagcct ctgttaagga ggagtcttca tcatccaaac ctggaaagaa    720

aatcccagca ggagctgttt ctgtattttt aggagacacg gatgtgtttg gtgctgcctc    780

cgttccatca ctgaaggagc cacagaagcc tgagcagccc actccaagga aaagccccta    840

tggtccccct cccactggcc tctttgatga tgatgatggt gatgatgatg acgacttttt    900

ctcggcaccc cacagcaaac cttctaaaac acgcaaagtc caatccactg ccgatatctt    960

tggtgacgaa gaaggagatc tgttcaaaga aaaagccgta gcatcgccag aagccactgt   1020

gagtcagaca gatgaaaata aagcaagagc agaaaaaaag gatttgtttt cttctcaaag   1080

tgcgagtaac ttaaaaggtg catctctgct gcctggcaag ctccccacgt cggtttccct   1140

gtttgatgat gaagatgaag aggataatct ttttgggggt acagctgcta agaagcagac   1200

attgtctcta caagctcaga gagaagagaa agcaaaagcc tccgagctct ccaaaaagaa   1260

agcatctgcc ctgttgttca gcagtgatga ggaggaccag tggaatattc ctgcttcaca   1320

gacccactta gcatctgaca gcaggtctaa aggagaaccc agggattctg ggaccctcca   1380

gagccaggag gccaaggctg tgaaaaagac cagtctcttt gaggaagaca aagaagatga   1440

tctttttgcc attgccaagg acagatacat cctacctcct attgttcccg aagttgtctg   1500

tcaagttttg tgtatggaaa gtaattcata ccttcatcag atctcaaaag aagctttaca   1560

cacacaagaa gaagttgagc caaaagaaga cccagagagt gtcactcctc tttgaagacg   1620

atgttgatag cggaggctct ctgtttggct ctcctcccac atctgttcct cctgcaacaa   1680

agaaaaaaga gactgtctct gaggcaccac ctttgctgtt cagcgatgaa gaagagaagg   1740

aggcacaact tggagtgaag tctgtggata agaaggttga gagtgccaag gagtcattaa   1800

aatttgggag aactgatgtg gctgagtcag aaaaggaagg acttttgact agatctgctc   1860

aggaaacagt caagcattct gatttatttt cttcatcatc cccatgggac aaaggaacca   1920

agcctagaac caaaactgtt cttagcttgt ttgatgagga agaggataaa atggaagatc   1980

aaaacattat ccaggctcca cagaaagaag taggaaaggg ctgcgatcct gatgcccacc   2040

ccaagagcac aggtgtcttc caggatgaag agctgctttt cagccacaag ctccaaaagg   2100

acaatgaccc agatgttgac ctttttgctg gcaccaaaaa aaccaagctg ttagagccaa   2160

gtgttgggag cctgtttggg gatgatgaag atgatgatct tttcagctct gccaagtccc   2220

agcctttggt acaagagaaa aagagagtag tgaaaaaaga ccactctgtt aactctttca   2280

aaaaccagaa acatcctgaa tccattcaag gtagtaaaga aaaaggcata tggaagccgg   2340

aaacacctca ggcaaattta gcgatcaacc cagcggcctt gctgcccaca gcggcttccc   2400

agatctctga agtaaagcct gttttgccag aattggcttt tccttcatct gaacacagaa   2460

ggagccacgg tctggaaagt gtgcctgtcc ttcccgggag tggggaggcc ggtgtgagtt   2520

ttgatcttcc agctcaggca gacaccttac acagtgcaaa caagagccgt gtcaagatga   2580

gagggaagcg tagaccgcag acccgtgcag ctaggcggct ggctgctcag gagtccagcg   2640

aggctgagga catgagcgtc cccagaggac ccattgcaca gtgggctgat ggcgccattt   2700

ccccaaatgg ccatcggcca cagctcagag cagccagtgg agaagacagc actgaggagg   2760

ccctggcagc tgccgctgca ccttgggaag gtggtcctgt gcctggagtg gacacaagcc   2820

cctttgcaaa gtctctgggt cattccagag gggaggctga cctttttgat tctggggaca   2880

ttttttccac gggcactgga tctcagtccg tggagagaac aaaacccaag gcaaagatag   2940

cagagaatcc tgccaaccca ccagtgggtg gtaaagcaaa gagccccatg tttcctgctc   3000

taggcgaggc cagcagtgat gatgatctct ttcagtctgc taaaccaaaa ccagcaaaga   3060

aaacaaatcc ctttcctctc ctggaagatg aggatgacct ctttacagat cagaaagtca   3120

agaagaatga gacaaaatcc agtagtcagc aggatgtcat attaacaaca caagatattt   3180

ttgaggatga tatatttgct acggaagcaa ttaaaccctc tcagaaaacc agagagaagg   3240

agaaaacatt ggaatctaat ttatttgatg ataacattga tatctttgct gacttaactg   3300

taaaaccaaa agaaaagtcc aaaaagaaag tggaagccaa gtctatattt gatgatgata   3360

tggatgacat cttctccact ggtatccagg ctaagacaac caaaccaaaa agccgatctg   3420

cacaggccgc acctgaacca agatttgaac acaaggtgtc caacatcttt gatgatcccc   3480

tgaatgcctt tggaggccag tagagcacac agggtatcca catgttaccc tgcagctaca   3540

ttgttgagtt agtgatgata ttgtatatgc tcatggtctt aactggatta caaaaagcaa   3600

atactagaac agctagctca tcttttaccc aatgtactta gtatttttct gcactggttt   3660

aatcatgctt aatactacaa aacaaaaata aatatttcac agtggttggt ttgttttgtt   3720

tttaaaccac agtttgattt agttagcctt gctggggcca taatatgctt cagggtgtgt   3780

aaaagaagaa atctctttgt ggctttcatg ggcagggaat ctcagagata gcaaatgcca   3840

cctgaccaga agtctttgtt atatggatgg gaaccctaac ttagggcttg ggcaggggaa   3900

agagaaagaa gatgagagat tatacttcat gagtcttagc aatatgggag caggttttca   3960

ctgaattctg agggtgcctc tgcatgtcct ccaaggcaaa gtttggcaaa ctgtggcccc   4020

cccactgtca tattttgtta ataaaatttt attggaacac aatcaca                 4067


<210>  6775
<211>  688
<212>  PRT
<213>  Homo sapiens

<400>  6775

Met Ile Phe Leu Pro Leu Pro Arg Thr Asp Thr Ser Tyr Leu Leu Leu 
1               5                   10                  15


Phe Pro Lys Leu Ser Val Lys Phe Cys Val Trp Lys Val Ile His Thr 
            20                  25                  30


Phe Ile Arg Ser Gln Lys Lys Leu Tyr Thr His Lys Lys Lys Leu Ser 
        35                  40                  45


Gln Lys Lys Thr Gln Arg Val Ser Leu Leu Phe Glu Asp Asp Val Asp 
    50                  55                  60


Ser Gly Gly Ser Leu Phe Gly Ser Pro Pro Thr Ser Val Pro Pro Ala 
65                  70                  75                  80


Thr Lys Lys Lys Glu Thr Val Ser Glu Ala Pro Pro Leu Leu Phe Ser 
                85                  90                  95


Asp Glu Glu Glu Lys Glu Ala Gln Leu Gly Val Lys Ser Val Asp Lys 
            100                 105                 110


Lys Val Glu Ser Ala Lys Glu Ser Leu Lys Phe Gly Arg Thr Asp Val 
        115                 120                 125


Ala Glu Ser Glu Lys Glu Gly Leu Leu Thr Arg Ser Ala Gln Glu Thr 
    130                 135                 140


Val Lys His Ser Asp Leu Phe Ser Ser Ser Ser Pro Trp Asp Lys Gly 
145                 150                 155                 160


Thr Lys Pro Arg Thr Lys Thr Val Leu Ser Leu Phe Asp Glu Glu Glu 
                165                 170                 175


Asp Lys Met Glu Asp Gln Asn Ile Ile Gln Ala Pro Gln Lys Glu Val 
            180                 185                 190


Gly Lys Gly Cys Asp Pro Asp Ala His Pro Lys Ser Thr Gly Val Phe 
        195                 200                 205


Gln Asp Glu Glu Leu Leu Phe Ser His Lys Leu Gln Lys Asp Asn Asp 
    210                 215                 220


Pro Asp Val Asp Leu Phe Ala Gly Thr Lys Lys Thr Lys Leu Leu Glu 
225                 230                 235                 240


Pro Ser Val Gly Ser Leu Phe Gly Asp Asp Glu Asp Asp Asp Leu Phe 
                245                 250                 255


Ser Ser Ala Lys Ser Gln Pro Leu Val Gln Glu Lys Lys Arg Val Val 
            260                 265                 270


Lys Lys Asp His Ser Val Asn Ser Phe Lys Asn Gln Lys His Pro Glu 
        275                 280                 285


Ser Ile Gln Gly Ser Lys Glu Lys Gly Ile Trp Lys Pro Glu Thr Pro 
    290                 295                 300


Gln Ala Asn Leu Ala Ile Asn Pro Ala Ala Leu Leu Pro Thr Ala Ala 
305                 310                 315                 320


Ser Gln Ile Ser Glu Val Lys Pro Val Leu Pro Glu Leu Ala Phe Pro 
                325                 330                 335


Ser Ser Glu His Arg Arg Ser His Gly Leu Glu Ser Val Pro Val Leu 
            340                 345                 350


Pro Gly Ser Gly Glu Ala Gly Val Ser Phe Asp Leu Pro Ala Gln Ala 
        355                 360                 365


Asp Thr Leu His Ser Ala Asn Lys Ser Arg Val Lys Met Arg Gly Lys 
    370                 375                 380


Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala Ala Gln Glu Ser 
385                 390                 395                 400


Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro Ile Ala Gln Trp 
                405                 410                 415


Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro Gln Leu Arg Ala 
            420                 425                 430


Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala Ala Ala Ala Ala 
        435                 440                 445


Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr Ser Pro Phe Ala 
    450                 455                 460


Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu Phe Asp Ser Gly 
465                 470                 475                 480


Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val Glu Arg Thr Lys 
                485                 490                 495


Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro Pro Val Gly Gly 
            500                 505                 510


Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu Ala Ser Ser Asp 
        515                 520                 525


Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala Lys Lys Thr Asn 
    530                 535                 540


Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe Thr Asp Gln Lys 
545                 550                 555                 560


Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln Asp Val Ile Leu 
                565                 570                 575


Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala Thr Glu Ala Ile 
            580                 585                 590


Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr Leu Glu Ser Asn 
        595                 600                 605


Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu Thr Val Lys Pro 
    610                 615                 620


Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser Ile Phe Asp Asp 
625                 630                 635                 640


Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala Lys Thr Thr Lys 
                645                 650                 655


Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro Arg Phe Glu His 
            660                 665                 670


Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala Phe Gly Gly Gln 
        675                 680                 685


<210>  6776
<211>  357
<212>  DNA
<213>  Homo sapiens

<400>  6776
atgacctaca agaatgtttt ggatcaagtg gagatacaaa ggaggaggca gccatgtcct     60

gaccattgtc tttctttccc gtcctggctg gagagagcac agtggggaag agaaataaga    120

gagaagacaa cccaaacctt aactctcatg cagtactggg cggtggataa tctttttggg    180

ggtacagctg ctaagaagca gacattgtct ctacaagctc agagagaaga gaaagcaaaa    240

gcctccgagc tctccaaaaa gaaagcatct gccctgttgt tcagcagtga tgaggagtct    300

gatgaagaag cggacagttt tgggggagca cgattagatg aaaggggtgt gacctga       357


<210>  6777
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  6777

Met Thr Tyr Lys Asn Val Leu Asp Gln Val Glu Ile Gln Arg Arg Arg 
1               5                   10                  15


Gln Pro Cys Pro Asp His Cys Leu Ser Phe Pro Ser Trp Leu Glu Arg 
            20                  25                  30


Ala Gln Trp Gly Arg Glu Ile Arg Glu Lys Thr Thr Gln Thr Leu Thr 
        35                  40                  45


Leu Met Gln Tyr Trp Ala Val Asp Asn Leu Phe Gly Gly Thr Ala Ala 
    50                  55                  60


Lys Lys Gln Thr Leu Ser Leu Gln Ala Gln Arg Glu Glu Lys Ala Lys 
65                  70                  75                  80


Ala Ser Glu Leu Ser Lys Lys Lys Ala Ser Ala Leu Leu Phe Ser Ser 
                85                  90                  95


Asp Glu Glu Ser Asp Glu Glu Ala Asp Ser Phe Gly Gly Ala Arg Leu 
            100                 105                 110


Asp Glu Arg Gly Val Thr 
        115


<210>  6778
<211>  528
<212>  DNA
<213>  Homo sapiens

<400>  6778
atgtgcgcac tgtgctgctt aggtctaaga tctcccaggg cctgtgtgaa gagcgttgca     60

tttgcatttg ctgctgaggc tccttggagc tacagtgata caagcatttc atttgtacct    120

gtgttcctgt gtgaaattct cttcctagtg gctgtgtgtg gaccccagtc ctatcccagt    180

cctggtccac acttgactct gactggttgc tgtactgccc tctccctgag tgaaggactt    240

ttgactagat ctgctcagga aacagtcaag cattctgatt tattttcttc atcatcccca    300

tgggacaaag gaaccaagcc tagaaccaaa actgttctta gcttgtttga tgaggaagag    360

gataaaatgg aagatcaaaa cattatccag gctccacaga aagaagtagg aaagggcacc    420

atctggaaag tcaaacgacc acccacaaaa tgggagaaaa gatttacaga tcatgtattt    480

gataaaggac tcagatccag aatatgtaaa agacttataa gtcaataa                 528


<210>  6779
<211>  175
<212>  PRT
<213>  Homo sapiens

<400>  6779

Met Cys Ala Leu Cys Cys Leu Gly Leu Arg Ser Pro Arg Ala Cys Val 
1               5                   10                  15


Lys Ser Val Ala Phe Ala Phe Ala Ala Glu Ala Pro Trp Ser Tyr Ser 
            20                  25                  30


Asp Thr Ser Ile Ser Phe Val Pro Val Phe Leu Cys Glu Ile Leu Phe 
        35                  40                  45


Leu Val Ala Val Cys Gly Pro Gln Ser Tyr Pro Ser Pro Gly Pro His 
    50                  55                  60


Leu Thr Leu Thr Gly Cys Cys Thr Ala Leu Ser Leu Ser Glu Gly Leu 
65                  70                  75                  80


Leu Thr Arg Ser Ala Gln Glu Thr Val Lys His Ser Asp Leu Phe Ser 
                85                  90                  95


Ser Ser Ser Pro Trp Asp Lys Gly Thr Lys Pro Arg Thr Lys Thr Val 
            100                 105                 110


Leu Ser Leu Phe Asp Glu Glu Glu Asp Lys Met Glu Asp Gln Asn Ile 
        115                 120                 125


Ile Gln Ala Pro Gln Lys Glu Val Gly Lys Gly Thr Ile Trp Lys Val 
    130                 135                 140


Lys Arg Pro Pro Thr Lys Trp Glu Lys Arg Phe Thr Asp His Val Phe 
145                 150                 155                 160


Asp Lys Gly Leu Arg Ser Arg Ile Cys Lys Arg Leu Ile Ser Gln 
                165                 170                 175


<210>  6780
<211>  2605
<212>  DNA
<213>  Homo sapiens

<400>  6780
agtcatctcc cctctcctca ctccacacgc cagagtttca tgaatctata ctttaatagt     60

tagtgttttt tgatgccatg ccagatttga ctctgaagtg gagttaaggt aggatgaaga    120

atcttcttcc cactaaagaa tttatttctc cctctggatt tccttggaat agaattaaaa    180

tagaaataaa tataaattac atctgatttc ctgcctgctc tcagtgttgc ctctcccgag    240

gtcattgctg ttgggccgta ctctgcagca gtcttctcag aacgctgtgg agctcctcct    300

gggaacagcc caggactgga gagcgagtga cagttccacg tgcaggtgtc ccagggtgtc    360

tcactgaagc cttagtgtcc tgagccgtaa acctgaggca cttggacgaa cacatcacca    420

ctgacccttc ctggggctca gatcttttgc ttttagagcc agtgcattag gctatggttg    480

aatttttgtg tgctccttga aatttctatt tgataaccaa catggtaatt ttgcctgctg    540

gtcagtttta ggtgctctga taaactgtga ctcttgggaa tcttactcat cttgtattcc    600

ttgactccat atctgatctg gcagctttcc acttatgtga cagaggagga ggcatacgtg    660

aagtagtgct agtgaaacat caggccccag gagagatttg aatgcctttc ccattaaaga    720

gctacagaaa gtgacagttt tgctccatca cagatttatt tacaggcata agaaacactt    780

gtctttctgt ttcccaaatg gatttttaac tggatgtaat cttacacagg actcatcagg    840

tctcgctcca tttaaaacca aagaaccatc cactcggatc gggaagatac aagtaattaa    900

aacactggaa tcttcattgc ctgccctgtg gcatctataa acttttttgg gtttcctact    960

cttgtcagct gctgccaaac atcttctcat ctcttccccc gcctcccctc ccctgcacct   1020

agttgttgtc tcctgtgtgc tgcgtcttta acatctattc tttgagccca gtggtgggca   1080

taggtgtaag acgctctgtt ttaattctga gactagattg ggcgattttc ctacgtttct   1140

ctactcctct cgtattatac attatgtgta ccgaatcttg tcatgtgtca caataaagat   1200

aatagactgc tgtgttgaag aacaaataca gagtttcatt tttcttcttt aggcaaattt   1260

agcgatcaac ccagcggcct tgctgcccac agcggcttcc cagatctctg aagtaaagcc   1320

tgttttgcca gaattggctt ttccttcatc tgaacacaga aggagccacg gtctggaaag   1380

tgtgcctgtc cttcccggga gtggggaggc cggtgtgagt tttgatcttc cagctcaggc   1440

agacacctta cacagtgcaa acaagagccg tgtcaagatg agagggaagc gtagaccgca   1500

gacccgtgca gctaggcggc tggctgctca ggagtccagc gaggctgagg acatgagcgt   1560

ccccagagga cccattgcac agtgggctga tggcgccatt tccccaaatg gccatcggcc   1620

acagctcaga gcagccagtg gagaagacag cactgaggag gccctggcag ctgccgctgc   1680

accttgggaa ggtggtcctg tgcctggagt ggacacaagc ccctttgcaa agtctctggg   1740

tcattccaga ggggaggctg acctttttga ttctggggac attttttcca cgggcactgg   1800

atctcagtcc gtggagagaa caaaacccaa ggcaaagata gcagagaatc ctgccaaccc   1860

accagtgggt ggtaaagcaa agagccccat gtttcctgct ctaggcgagg ccagcagtga   1920

tgatgatctc tttcagtctg ctaaaccaaa accagcaaag aaaacaaatc cctttcctct   1980

cctggaagat gaggatgacc tctttacaga tcagaaagtc aagaagaatg agacaaaatc   2040

cagtagtcag caggatgtca tattaacaac acaagatatt tttgaggatg atatatttgc   2100

tacggaagca attaaaccct ctcagaaaac cagagagaag gagaaaacat tggaatctaa   2160

tttatttgat gataacattg atatctttgc tgacttaact gtaaaaccaa aagaaaagtc   2220

caaaaagaaa gtggaagcca agtctatatt tgatgatgat atggatgaca tcttctccac   2280

tggtatccag gctaagacaa ccaaaccaaa aagccgatct gcacaggccg cacctgaacc   2340

aagatttgaa cacaaggtgt ccaacatctt tgatgatccc ctgaatgcct ttggaggcca   2400

gtagagcaca cagggtatcc acatgttacc ctgcagctac attgttgagt tagtgatgat   2460

attgtatatg ctcatggtct taactggatt acaaaaagca aatactagaa cagctagctc   2520

atcttttacc caatgtactt agtatttttc tgcactggtt taatcatgct taatactaca   2580

aaacaaaaat aaatatttca cagtg                                         2605


<210>  6781
<211>  308
<212>  PRT
<213>  Homo sapiens

<400>  6781

Met Arg Gly Lys Arg Arg Pro Gln Thr Arg Ala Ala Arg Arg Leu Ala 
1               5                   10                  15


Ala Gln Glu Ser Ser Glu Ala Glu Asp Met Ser Val Pro Arg Gly Pro 
            20                  25                  30


Ile Ala Gln Trp Ala Asp Gly Ala Ile Ser Pro Asn Gly His Arg Pro 
        35                  40                  45


Gln Leu Arg Ala Ala Ser Gly Glu Asp Ser Thr Glu Glu Ala Leu Ala 
    50                  55                  60


Ala Ala Ala Ala Pro Trp Glu Gly Gly Pro Val Pro Gly Val Asp Thr 
65                  70                  75                  80


Ser Pro Phe Ala Lys Ser Leu Gly His Ser Arg Gly Glu Ala Asp Leu 
                85                  90                  95


Phe Asp Ser Gly Asp Ile Phe Ser Thr Gly Thr Gly Ser Gln Ser Val 
            100                 105                 110


Glu Arg Thr Lys Pro Lys Ala Lys Ile Ala Glu Asn Pro Ala Asn Pro 
        115                 120                 125


Pro Val Gly Gly Lys Ala Lys Ser Pro Met Phe Pro Ala Leu Gly Glu 
    130                 135                 140


Ala Ser Ser Asp Asp Asp Leu Phe Gln Ser Ala Lys Pro Lys Pro Ala 
145                 150                 155                 160


Lys Lys Thr Asn Pro Phe Pro Leu Leu Glu Asp Glu Asp Asp Leu Phe 
                165                 170                 175


Thr Asp Gln Lys Val Lys Lys Asn Glu Thr Lys Ser Ser Ser Gln Gln 
            180                 185                 190


Asp Val Ile Leu Thr Thr Gln Asp Ile Phe Glu Asp Asp Ile Phe Ala 
        195                 200                 205


Thr Glu Ala Ile Lys Pro Ser Gln Lys Thr Arg Glu Lys Glu Lys Thr 
    210                 215                 220


Leu Glu Ser Asn Leu Phe Asp Asp Asn Ile Asp Ile Phe Ala Asp Leu 
225                 230                 235                 240


Thr Val Lys Pro Lys Glu Lys Ser Lys Lys Lys Val Glu Ala Lys Ser 
                245                 250                 255


Ile Phe Asp Asp Asp Met Asp Asp Ile Phe Ser Thr Gly Ile Gln Ala 
            260                 265                 270


Lys Thr Thr Lys Pro Lys Ser Arg Ser Ala Gln Ala Ala Pro Glu Pro 
        275                 280                 285


Arg Phe Glu His Lys Val Ser Asn Ile Phe Asp Asp Pro Leu Asn Ala 
    290                 295                 300


Phe Gly Gly Gln 
305


<210>  6782
<211>  3017
<212>  DNA
<213>  Homo sapiens

<400>  6782
acttggttgc taattggacc cactctactg aggctttgta tagaactcat agaggaagat     60

ggcttcaagt aatgaactac cctttgcttt tcttaggact aaaatctcag gaagctggtg    120

atgaatgaaa accttagtcc caatggcact gcacgagggg ccaggagagc agcagcatca    180

taagccacag ggtggggcag ccaaggcagg ggcattctga gctgttgggg aggggtggca    240

ggcagggtgg ggcactgtga ggtgtcgggg agggcattgt gaagtgtggg gtggggcatt    300

gtgtgccaca tgcctgggct cccacctggg gccagtgggc ttcagtctgt aggtgactac    360

agaaggagga ggagctccgt ctgttctctc ttcaggcagt tgttgtgtct ctcagcactt    420

gttgggttca caacctatta aataagccgg ctggtcttca ccctcccaga caagtcaact    480

caggggaggc agcagggtgc gggccttggc ccgcagccct agccggggcc ggggccaggg    540

ccagggccag ggctggtgcc cggggccgcg ctgtgaggtg ggcaggcgag gagcgggaag    600

accatctctg caagtgcagc atagcctcgg cctaggacag cgggagtgcg tggccaaagc    660

tgtgagcaga ggcacaggtg gtggcagaca gtagaggcgc cccatgggga acatactgac    720

ctgtcgtgtg caccctagcg tcagcctcga gtttgaccag cagcaggggt cggtgtgtcc    780

ctctgaatct gagatctatg aggcaggagc tggggacagg atggcaggag cgcccatggc    840

tgctgctgta cagcctgctg aggtgactgt tgaagttggt gaggacctcc acatgcacca    900

cgttcgtgac cgggagatgc ctgaagcttt ggagtttaac ccttctgcca atccagaggc    960

aagcacaata ttccagagga actctcaaac agatgttgta gaaataagaa gaagcaactg   1020

tacaaaccat gtatctactg tgcgtttcag tcaacaatac agcttgtgtt cgacaatatt   1080

ccttgatgac agcacagcca tccagcatta tcttacaatg acaataatat ctgtgacctt   1140

ggagatacct catcatatca cacaaagaga tgcagataga tctttgagca tacctgatga   1200

acagttacac tcatttgcgg tttccaccgt gcacattatg aagaaaagaa atggaggtgg   1260

gagtttaaat aactattcct cctccattcc atcgactccc agcaccagcc aggaggaccc   1320

tcagttcagt gttcctccca ctgccaacac acccaccccc gtttgcaagc ggtccatgcg   1380

ctggtccaac ctgtttacat ctgagaaagg gagtgaccca gacaaagaga ggaaagcccc   1440

ggagaatcat gctgacacca tcgggagcgg cagagccatc cccattaaac agggcatgct   1500

cttaaagcga agtgggaaat ggctgaagac atggaaaaag aaatacgtca ccctgtgttc   1560

caatggcgtg ctcacctatt attcaagctt aggtgattat atgaagaata ttcataaaaa   1620

agagattgac cttcagacat ctaccatcaa agtcccagga aagtggccat ccctagccac   1680

atcggcctgc acacccatct ccacctctaa aagcaatggc ctatccaagg acatggacac   1740

cgggctgggt gactccatat gcttcagccc cagtatctcc agcaccacca gccccaagct   1800

caacccgccc ccctctcctc atgccaataa aaagaaacac ctaaagaaga aaagcaccaa   1860

caactttatg attgtgtctg ccactggcca aacgtggcac tttgaagcca cgacgtatga   1920

ggagcgggat gcctgggtcc aagccatcca gagccagatc ctggccagcc tgcagtcatg   1980

cgagagcagt aaaagcaagt cccagctgac cagccagagc aaggccatgg ccctgcagtc   2040

gatccaaaac atgcgtggga acgcccactg tgtggactgt gagacccaga atcctaagtg   2100

ggccagtttg aacttgggag tcctcatgtg tattgaatgc tcaggaatcc accgcagtct   2160

tggcacccgc ctttcccgtg tgcgatctct ggagctggat gactggccag ttgagctcag   2220

gaaggttatg tcatctattg gcaatgacct agccaacagc atctgggaag ggagcagcca   2280

ggggcagaca aaaccctcag aaaagtccac gagggaagag aaggaacggt ggatccgttc   2340

caaatatgag gagaagctct ttctggcccc actaccctgc actgagctgt ccctgggcca   2400

gcagctgctg cgggccaccg ctgatgagga cctgcagaca gccatcctgc tgctggcaca   2460

tggctcccgt gaggaggtga acgagacctg tggggaggga gacggctgca cggcgctcca   2520

tctggcctgc cgcaagggga atgtggtcct ggcgcagctc ctgatctggt acggggtgga   2580

cgtcatggcc cgagatgccc acgggaacac agcgctgacc tacgcccggc aggcctccag   2640

ccaggagtgc atcaacgtgc ttctgcagta cggctgcccc gacaagtgtg tgtagtatct   2700

gttttatttg actgcagtct ccttggtgca aaaacaaaat gggaaaaata aggataactc   2760

agaatttcaa aaggaaatca caaattcagc taataatagc attttcagta cttttcgtaa   2820

actaagtaaa tacacaaaat gttgattttt ctgaccataa gacgtatttt atgtcctttt   2880

gccaaggtgg atttgttagt ctcaggccct cctggccaca ttgcccaagt cacacaggct   2940

tctgtattat gtatttagat aaaatgtgtg aaaatatatt tgaaataaag ttcataaata   3000

tgcattgatt tttgtac                                                  3017


<210>  6783
<211>  663
<212>  PRT
<213>  Homo sapiens

<400>  6783

Met Gly Asn Ile Leu Thr Cys Arg Val His Pro Ser Val Ser Leu Glu 
1               5                   10                  15


Phe Asp Gln Gln Gln Gly Ser Val Cys Pro Ser Glu Ser Glu Ile Tyr 
            20                  25                  30


Glu Ala Gly Ala Gly Asp Arg Met Ala Gly Ala Pro Met Ala Ala Ala 
        35                  40                  45


Val Gln Pro Ala Glu Val Thr Val Glu Val Gly Glu Asp Leu His Met 
    50                  55                  60


His His Val Arg Asp Arg Glu Met Pro Glu Ala Leu Glu Phe Asn Pro 
65                  70                  75                  80


Ser Ala Asn Pro Glu Ala Ser Thr Ile Phe Gln Arg Asn Ser Gln Thr 
                85                  90                  95


Asp Val Val Glu Ile Arg Arg Ser Asn Cys Thr Asn His Val Ser Thr 
            100                 105                 110


Val Arg Phe Ser Gln Gln Tyr Ser Leu Cys Ser Thr Ile Phe Leu Asp 
        115                 120                 125


Asp Ser Thr Ala Ile Gln His Tyr Leu Thr Met Thr Ile Ile Ser Val 
    130                 135                 140


Thr Leu Glu Ile Pro His His Ile Thr Gln Arg Asp Ala Asp Arg Ser 
145                 150                 155                 160


Leu Ser Ile Pro Asp Glu Gln Leu His Ser Phe Ala Val Ser Thr Val 
                165                 170                 175


His Ile Met Lys Lys Arg Asn Gly Gly Gly Ser Leu Asn Asn Tyr Ser 
            180                 185                 190


Ser Ser Ile Pro Ser Thr Pro Ser Thr Ser Gln Glu Asp Pro Gln Phe 
        195                 200                 205


Ser Val Pro Pro Thr Ala Asn Thr Pro Thr Pro Val Cys Lys Arg Ser 
    210                 215                 220


Met Arg Trp Ser Asn Leu Phe Thr Ser Glu Lys Gly Ser Asp Pro Asp 
225                 230                 235                 240


Lys Glu Arg Lys Ala Pro Glu Asn His Ala Asp Thr Ile Gly Ser Gly 
                245                 250                 255


Arg Ala Ile Pro Ile Lys Gln Gly Met Leu Leu Lys Arg Ser Gly Lys 
            260                 265                 270


Trp Leu Lys Thr Trp Lys Lys Lys Tyr Val Thr Leu Cys Ser Asn Gly 
        275                 280                 285


Val Leu Thr Tyr Tyr Ser Ser Leu Gly Asp Tyr Met Lys Asn Ile His 
    290                 295                 300


Lys Lys Glu Ile Asp Leu Gln Thr Ser Thr Ile Lys Val Pro Gly Lys 
305                 310                 315                 320


Trp Pro Ser Leu Ala Thr Ser Ala Cys Thr Pro Ile Ser Thr Ser Lys 
                325                 330                 335


Ser Asn Gly Leu Ser Lys Asp Met Asp Thr Gly Leu Gly Asp Ser Ile 
            340                 345                 350


Cys Phe Ser Pro Ser Ile Ser Ser Thr Thr Ser Pro Lys Leu Asn Pro 
        355                 360                 365


Pro Pro Ser Pro His Ala Asn Lys Lys Lys His Leu Lys Lys Lys Ser 
    370                 375                 380


Thr Asn Asn Phe Met Ile Val Ser Ala Thr Gly Gln Thr Trp His Phe 
385                 390                 395                 400


Glu Ala Thr Thr Tyr Glu Glu Arg Asp Ala Trp Val Gln Ala Ile Gln 
                405                 410                 415


Ser Gln Ile Leu Ala Ser Leu Gln Ser Cys Glu Ser Ser Lys Ser Lys 
            420                 425                 430


Ser Gln Leu Thr Ser Gln Ser Lys Ala Met Ala Leu Gln Ser Ile Gln 
        435                 440                 445


Asn Met Arg Gly Asn Ala His Cys Val Asp Cys Glu Thr Gln Asn Pro 
    450                 455                 460


Lys Trp Ala Ser Leu Asn Leu Gly Val Leu Met Cys Ile Glu Cys Ser 
465                 470                 475                 480


Gly Ile His Arg Ser Leu Gly Thr Arg Leu Ser Arg Val Arg Ser Leu 
                485                 490                 495


Glu Leu Asp Asp Trp Pro Val Glu Leu Arg Lys Val Met Ser Ser Ile 
            500                 505                 510


Gly Asn Asp Leu Ala Asn Ser Ile Trp Glu Gly Ser Ser Gln Gly Gln 
        515                 520                 525


Thr Lys Pro Ser Glu Lys Ser Thr Arg Glu Glu Lys Glu Arg Trp Ile 
    530                 535                 540


Arg Ser Lys Tyr Glu Glu Lys Leu Phe Leu Ala Pro Leu Pro Cys Thr 
545                 550                 555                 560


Glu Leu Ser Leu Gly Gln Gln Leu Leu Arg Ala Thr Ala Asp Glu Asp 
                565                 570                 575


Leu Gln Thr Ala Ile Leu Leu Leu Ala His Gly Ser Arg Glu Glu Val 
            580                 585                 590


Asn Glu Thr Cys Gly Glu Gly Asp Gly Cys Thr Ala Leu His Leu Ala 
        595                 600                 605


Cys Arg Lys Gly Asn Val Val Leu Ala Gln Leu Leu Ile Trp Tyr Gly 
    610                 615                 620


Val Asp Val Met Ala Arg Asp Ala His Gly Asn Thr Ala Leu Thr Tyr 
625                 630                 635                 640


Ala Arg Gln Ala Ser Ser Gln Glu Cys Ile Asn Val Leu Leu Gln Tyr 
                645                 650                 655


Gly Cys Pro Asp Lys Cys Val 
            660


<210>  6784
<211>  2701
<212>  DNA
<213>  Homo sapiens

<400>  6784
ctgataggaa gtgaaaggtg gctgaggtaa tgagaataga cccatctgca gaggatcata     60

aaaccagcaa agacaagatc ttgtctaaga tgccttcaca aactttgtcc atgagaactg    120

taaggtcttc tccagacctg ttggctgctg ctgtgatctc tgcccaagag gagcttctga    180

ccaacatcca aagggcttct ggacccactg gactcctctg gagttgctcc ttcacatgtt    240

cccactctct gtgcggccac catggaagtc ggacctgccc ttctgccatg attgactaaa    300

atctcaggaa gctggtgatg aatgaaaacc ttagtcccaa tggcactgca cgaggggcca    360

ggagagcagc agcatcataa gccacaggcg tcagcctcga gtttgaccag cagcaggggt    420

cggtgtgtcc ctctgaatct gagatctatg aggcaggagc tggggacagg atggcaggag    480

cgcccatggc tgctgctgta cagcctgctg aggtgactgt tgaagttggt gaggacctcc    540

acatgcacca cgttcgtgac cgggagatgc ctgaagcttt ggagtttaac ctttctgcca    600

atccagaggc aagcacaata ttccagagga actctcaaac agatgctttg gagtttaacc    660

cttctgccaa tccagaggca agcacaatat tccagaggaa ctctcaaaca gatggtatct    720

actgtgcgtt tcagtcaaca atacagcttg tgttcgacaa tattccttga tgacagcaca    780

gccatccagc attatcttac aatgacaata atatctgtga ccttggagat acctcatcat    840

atcacacaaa gagatgcaga tagatctttg agcatacctg atgaacagtt acactcattt    900

gcggtttcca ccgtgcacat tatgaagaaa agaaatggag gtgggagttt aaataactat    960

tcctcctcca ttccatcgac tcccagcacc agccaggagg accctcagtt cagtgttcct   1020

cccactgcca acacacccac ccccgtttgc aagcggtcca tgcgctggtc caacctgttt   1080

acatctgaga aagggagtga cccagacaaa gagaggaaag ccccggagaa tcatgctgac   1140

accatcggga gcggcagagc catccccatt aaacagggca tgctcttaaa gcgaagtggg   1200

aaatggctga agacatggaa aaagaaatac gtcaccctgt gttccaatgg cgtgctcacc   1260

tattattcaa gcttaggtga ttatatgaag aatattcata aaaaagagat tgaccttcag   1320

acatctacca tcaaagtccc aggaaagtgg ccatccctag ccacatcggc ctgcacaccc   1380

atctccacct ctaaaagcaa tggcctatcc aaggacatgg acaccgggct gggtgactcc   1440

atatgcttca gccccagtat ctccagcacc accagcccca agctcaaccc gcccccctct   1500

cctcatgcca ataaaaagaa acacctaaag aagaaaagca ccaacaactt tatgattgtg   1560

tctgccactg gccaaacgtg gcactttgaa gccacgacgt atgaggagcg ggatgcctgg   1620

gtccaagcca tccagagcca gatcctggcc agcctgcagt catgcgagag cagtaaaagc   1680

aagtcccagc tgaccagcca gagcaaggcc atggccctgc agtcgatcca aaacatgcgt   1740

gggaacgccc actgtgtgga ctgtgagacc cagaatccta agtgggccag tttgaacttg   1800

ggagtcctca tgtgtattga atgctcagga atccaccgca gtcttggcac ccgcctttcc   1860

cgtgtgcgat ctctggagct ggatgactgg ccagttgagc tcaggaaggt tatgtcatct   1920

attggcaatg acctagccaa cagcatctgg gaagggagca gccaggggca gacaaaaccc   1980

tcagaaaagt ccacgaggga agagaaggaa cggtggatcc gttccaaata tgaggagaag   2040

ctctttctgg ccccactacc ctgcactgag ctgtccctgg gccagcagct gctgcgggcc   2100

accgctgatg aggacctgca gacagccatc ctgctgctgg cacatggctc ccgtgaggag   2160

gtgaacgaga cctgtgggga gggagacggc tgcacggcgc tccatctggc ctgccgcaag   2220

gggaatgtgg tcctggcgca gctcctgatc tggtacgggg tggacgtcat ggcccgagat   2280

gcccacggga acacagcgct gacctacgcc cggcaggcct ccagccagga gtgcatcaac   2340

gtgcttctgc agtacggctg ccccgacaag tgtgtgtagt atctgtttta tttgactgca   2400

gtctccttgg tgcaaaaaca aaatgggaaa aataaggata actcagaatt tcaaaaggaa   2460

atcacaaatt cagctaataa tagcattttc agtacttttc gtaaactaag taaatacaca   2520

aaatgttgat ttttctgacc ataagacgta ttttatgtcc ttttgccaag gtggatttgt   2580

tagtctcagg ccctcctggc cacattgccc aagtcacaca ggcttctgta ttatgtattt   2640

agataaaatg tgtgaaaata tatttgaaat aaagttcata aatatgcatt gatttttgta   2700

c                                                                   2701


<210>  6785
<211>  578
<212>  PRT
<213>  Homo sapiens

<400>  6785

Met Leu Trp Ser Leu Thr Leu Leu Pro Ile Gln Arg Gln Ala Gln Tyr 
1               5                   10                  15


Ser Arg Gly Thr Leu Lys Gln Met Val Ser Thr Val Arg Phe Ser Gln 
            20                  25                  30


Gln Tyr Ser Leu Cys Ser Thr Ile Phe Leu Asp Asp Ser Thr Ala Ile 
        35                  40                  45


Gln His Tyr Leu Thr Met Thr Ile Ile Ser Val Thr Leu Glu Ile Pro 
    50                  55                  60


His His Ile Thr Gln Arg Asp Ala Asp Arg Ser Leu Ser Ile Pro Asp 
65                  70                  75                  80


Glu Gln Leu His Ser Phe Ala Val Ser Thr Val His Ile Met Lys Lys 
                85                  90                  95


Arg Asn Gly Gly Gly Ser Leu Asn Asn Tyr Ser Ser Ser Ile Pro Ser 
            100                 105                 110


Thr Pro Ser Thr Ser Gln Glu Asp Pro Gln Phe Ser Val Pro Pro Thr 
        115                 120                 125


Ala Asn Thr Pro Thr Pro Val Cys Lys Arg Ser Met Arg Trp Ser Asn 
    130                 135                 140


Leu Phe Thr Ser Glu Lys Gly Ser Asp Pro Asp Lys Glu Arg Lys Ala 
145                 150                 155                 160


Pro Glu Asn His Ala Asp Thr Ile Gly Ser Gly Arg Ala Ile Pro Ile 
                165                 170                 175


Lys Gln Gly Met Leu Leu Lys Arg Ser Gly Lys Trp Leu Lys Thr Trp 
            180                 185                 190


Lys Lys Lys Tyr Val Thr Leu Cys Ser Asn Gly Val Leu Thr Tyr Tyr 
        195                 200                 205


Ser Ser Leu Gly Asp Tyr Met Lys Asn Ile His Lys Lys Glu Ile Asp 
    210                 215                 220


Leu Gln Thr Ser Thr Ile Lys Val Pro Gly Lys Trp Pro Ser Leu Ala 
225                 230                 235                 240


Thr Ser Ala Cys Thr Pro Ile Ser Thr Ser Lys Ser Asn Gly Leu Ser 
                245                 250                 255


Lys Asp Met Asp Thr Gly Leu Gly Asp Ser Ile Cys Phe Ser Pro Ser 
            260                 265                 270


Ile Ser Ser Thr Thr Ser Pro Lys Leu Asn Pro Pro Pro Ser Pro His 
        275                 280                 285


Ala Asn Lys Lys Lys His Leu Lys Lys Lys Ser Thr Asn Asn Phe Met 
    290                 295                 300


Ile Val Ser Ala Thr Gly Gln Thr Trp His Phe Glu Ala Thr Thr Tyr 
305                 310                 315                 320


Glu Glu Arg Asp Ala Trp Val Gln Ala Ile Gln Ser Gln Ile Leu Ala 
                325                 330                 335


Ser Leu Gln Ser Cys Glu Ser Ser Lys Ser Lys Ser Gln Leu Thr Ser 
            340                 345                 350


Gln Ser Lys Ala Met Ala Leu Gln Ser Ile Gln Asn Met Arg Gly Asn 
        355                 360                 365


Ala His Cys Val Asp Cys Glu Thr Gln Asn Pro Lys Trp Ala Ser Leu 
    370                 375                 380


Asn Leu Gly Val Leu Met Cys Ile Glu Cys Ser Gly Ile His Arg Ser 
385                 390                 395                 400


Leu Gly Thr Arg Leu Ser Arg Val Arg Ser Leu Glu Leu Asp Asp Trp 
                405                 410                 415


Pro Val Glu Leu Arg Lys Val Met Ser Ser Ile Gly Asn Asp Leu Ala 
            420                 425                 430


Asn Ser Ile Trp Glu Gly Ser Ser Gln Gly Gln Thr Lys Pro Ser Glu 
        435                 440                 445


Lys Ser Thr Arg Glu Glu Lys Glu Arg Trp Ile Arg Ser Lys Tyr Glu 
    450                 455                 460


Glu Lys Leu Phe Leu Ala Pro Leu Pro Cys Thr Glu Leu Ser Leu Gly 
465                 470                 475                 480


Gln Gln Leu Leu Arg Ala Thr Ala Asp Glu Asp Leu Gln Thr Ala Ile 
                485                 490                 495


Leu Leu Leu Ala His Gly Ser Arg Glu Glu Val Asn Glu Thr Cys Gly 
            500                 505                 510


Glu Gly Asp Gly Cys Thr Ala Leu His Leu Ala Cys Arg Lys Gly Asn 
        515                 520                 525


Val Val Leu Ala Gln Leu Leu Ile Trp Tyr Gly Val Asp Val Met Ala 
    530                 535                 540


Arg Asp Ala His Gly Asn Thr Ala Leu Thr Tyr Ala Arg Gln Ala Ser 
545                 550                 555                 560


Ser Gln Glu Cys Ile Asn Val Leu Leu Gln Tyr Gly Cys Pro Asp Lys 
                565                 570                 575


Cys Val 



<210>  6786
<211>  2456
<212>  DNA
<213>  Homo sapiens

<400>  6786
gcagaagcag atgcacatct tctctgggaa aattcacctc tagtctacac ctatgaacct     60

actgggttgg tgacatttac aagacagagt cttgaagatt ttccagaatg ggaaagatgt    120

gaaaaaccct tgacacgatt gcatgtcact tacgaaggta ccatagaaga aaatggccga    180

ggcatgctac aggtggattt tgcaaatcat tttgttggag gtggtgtaac cagtgcagga    240

cttgtgcaag aagaaatccg ctttttaatc aatcctgagt tgattatttc acggctcttc    300

actgaggtgc tggatcacaa tgaatgtcta attatcacag tgtcagagat ggctttggat    360

tccccattct gtgtgctgct gtctggctcc tgaacccacc tgtagaggtg tgtcaatccc    420

agctggtgaa gtactgagaa gaagctacac aaaaggcatc aaagtattag tatctactgt    480

gcgtttcagt caacaataca gcttgtgttc gacaatattc cttgatgaca gcacagccat    540

ccagcattat cttacaatga caataatatc tgtgaccttg gagatacctc atcatatcac    600

acaaagagat gcagatagat ctttgagcat acctgatgaa cagttacact catttgcggt    660

ttccaccgtg cacattatga agaaaagaaa tggaggtggg agtttaaata actattcctc    720

ctccattcca tcgactccca gcaccagcca ggaggaccct cagttcagtg ttcctcccac    780

tgccaacaca cccacccccg tttgcaagcg gtccatgcgc tggtccaacc tgtttacatc    840

tgagaaaggg agtgacccag acaaagagag gaaagccccg gagaatcatg ctgacaccat    900

cgggagcggc agagccatcc ccattaaaca gggcatgctc ttaaagcgaa gtgggaaatg    960

gctgaagaca tggaaaaaga aatacgtcac cctgtgttcc aatggcgtgc tcacctatta   1020

ttcaagctta ggtgattata tgaagaatat tcataaaaaa gagattgacc ttcagacatc   1080

taccatcaaa gtcccaggaa agtggccatc cctagccaca tcggcctgca cacccatctc   1140

cacctctaaa agcaatggcc tatccaagga catggacacc gggctgggtg actccatatg   1200

cttcagcccc agtatctcca gcaccaccag ccccaagctc aacccgcccc cctctcctca   1260

tgccaataaa aagaaacacc taaagaagaa aagcaccaac aactttatga ttgtgtctgc   1320

cactggccaa acgtggcact ttgaagccac gacgtatgag gagcgggatg cctgggtcca   1380

agccatccag agccagatcc tggccagcct gcagtcatgc gagagcagta aaagcaagtc   1440

ccagctgacc agccagagca aggccatggc cctgcagtcg atccaaaaca tgcgtgggaa   1500

cgcccactgt gtggactgtg agacccagaa tcctaagtgg gccagtttga acttgggagt   1560

cctcatgtgt attgaatgct caggaatcca ccgcagtctt ggcacccgcc tttcccgtgt   1620

gcgatctctg gagctggatg actggccagt tgagctcagg aaggttatgt catctattgg   1680

caatgaccta gccaacagca tctgggaagg gagcagccag gggcagacaa aaccctcaga   1740

aaagtccacg agggaagaga aggaacggtg gatccgttcc aaatatgagg agaagctctt   1800

tctggcccca ctaccctgca ctgagctgtc cctgggccag cagctgctgc gggccaccgc   1860

tgatgaggac ctgcagacag ccatcctgct gctggcacat ggctcccgtg aggaggtgaa   1920

cgagacctgt ggggagggag acggctgcac ggcgctccat ctggcctgcc gcaaggggaa   1980

tgtggtcctg gcgcagctcc tgatctggta cggggtggac gtcatggccc gagatgccca   2040

cgggaacaca gcgctgacct acgcccggca ggcctccagc caggagtgca tcaacgtgct   2100

tctgcagtac ggctgccccg acaagtgtgt gtagtatctg ttttatttga ctgcagtctc   2160

cttggtgcaa aaacaaaatg ggaaaaataa ggataactca gaatttcaaa aggaaatcac   2220

aaattcagct aataatagca ttttcagtac ttttcgtaaa ctaagtaaat acacaaaatg   2280

ttgatttttc tgaccataag acgtatttta tgtccttttg ccaaggtgga tttgttagtc   2340

tcaggccctc ctggccacat tgcccaagtc acacaggctt ctgtattatg tatttagata   2400

aaatgtgtga aaatatattt gaaataaagt tcataaatat gcattgattt ttgtac       2456


<210>  6787
<211>  525
<212>  PRT
<213>  Homo sapiens

<400>  6787

Met Thr Ile Ile Ser Val Thr Leu Glu Ile Pro His His Ile Thr Gln 
1               5                   10                  15


Arg Asp Ala Asp Arg Ser Leu Ser Ile Pro Asp Glu Gln Leu His Ser 
            20                  25                  30


Phe Ala Val Ser Thr Val His Ile Met Lys Lys Arg Asn Gly Gly Gly 
        35                  40                  45


Ser Leu Asn Asn Tyr Ser Ser Ser Ile Pro Ser Thr Pro Ser Thr Ser 
    50                  55                  60


Gln Glu Asp Pro Gln Phe Ser Val Pro Pro Thr Ala Asn Thr Pro Thr 
65                  70                  75                  80


Pro Val Cys Lys Arg Ser Met Arg Trp Ser Asn Leu Phe Thr Ser Glu 
                85                  90                  95


Lys Gly Ser Asp Pro Asp Lys Glu Arg Lys Ala Pro Glu Asn His Ala 
            100                 105                 110


Asp Thr Ile Gly Ser Gly Arg Ala Ile Pro Ile Lys Gln Gly Met Leu 
        115                 120                 125


Leu Lys Arg Ser Gly Lys Trp Leu Lys Thr Trp Lys Lys Lys Tyr Val 
    130                 135                 140


Thr Leu Cys Ser Asn Gly Val Leu Thr Tyr Tyr Ser Ser Leu Gly Asp 
145                 150                 155                 160


Tyr Met Lys Asn Ile His Lys Lys Glu Ile Asp Leu Gln Thr Ser Thr 
                165                 170                 175


Ile Lys Val Pro Gly Lys Trp Pro Ser Leu Ala Thr Ser Ala Cys Thr 
            180                 185                 190


Pro Ile Ser Thr Ser Lys Ser Asn Gly Leu Ser Lys Asp Met Asp Thr 
        195                 200                 205


Gly Leu Gly Asp Ser Ile Cys Phe Ser Pro Ser Ile Ser Ser Thr Thr 
    210                 215                 220


Ser Pro Lys Leu Asn Pro Pro Pro Ser Pro His Ala Asn Lys Lys Lys 
225                 230                 235                 240


His Leu Lys Lys Lys Ser Thr Asn Asn Phe Met Ile Val Ser Ala Thr 
                245                 250                 255


Gly Gln Thr Trp His Phe Glu Ala Thr Thr Tyr Glu Glu Arg Asp Ala 
            260                 265                 270


Trp Val Gln Ala Ile Gln Ser Gln Ile Leu Ala Ser Leu Gln Ser Cys 
        275                 280                 285


Glu Ser Ser Lys Ser Lys Ser Gln Leu Thr Ser Gln Ser Lys Ala Met 
    290                 295                 300


Ala Leu Gln Ser Ile Gln Asn Met Arg Gly Asn Ala His Cys Val Asp 
305                 310                 315                 320


Cys Glu Thr Gln Asn Pro Lys Trp Ala Ser Leu Asn Leu Gly Val Leu 
                325                 330                 335


Met Cys Ile Glu Cys Ser Gly Ile His Arg Ser Leu Gly Thr Arg Leu 
            340                 345                 350


Ser Arg Val Arg Ser Leu Glu Leu Asp Asp Trp Pro Val Glu Leu Arg 
        355                 360                 365


Lys Val Met Ser Ser Ile Gly Asn Asp Leu Ala Asn Ser Ile Trp Glu 
    370                 375                 380


Gly Ser Ser Gln Gly Gln Thr Lys Pro Ser Glu Lys Ser Thr Arg Glu 
385                 390                 395                 400


Glu Lys Glu Arg Trp Ile Arg Ser Lys Tyr Glu Glu Lys Leu Phe Leu 
                405                 410                 415


Ala Pro Leu Pro Cys Thr Glu Leu Ser Leu Gly Gln Gln Leu Leu Arg 
            420                 425                 430


Ala Thr Ala Asp Glu Asp Leu Gln Thr Ala Ile Leu Leu Leu Ala His 
        435                 440                 445


Gly Ser Arg Glu Glu Val Asn Glu Thr Cys Gly Glu Gly Asp Gly Cys 
    450                 455                 460


Thr Ala Leu His Leu Ala Cys Arg Lys Gly Asn Val Val Leu Ala Gln 
465                 470                 475                 480


Leu Leu Ile Trp Tyr Gly Val Asp Val Met Ala Arg Asp Ala His Gly 
                485                 490                 495


Asn Thr Ala Leu Thr Tyr Ala Arg Gln Ala Ser Ser Gln Glu Cys Ile 
            500                 505                 510


Asn Val Leu Leu Gln Tyr Gly Cys Pro Asp Lys Cys Val 
        515                 520                 525


<210>  6788
<211>  933
<212>  DNA
<213>  Homo sapiens

<400>  6788
gagagggagt ctcactctgt cgcccatgct ggagttctgt ggcacagtct tggctcactg     60

caacctctgc ctcccagaga cgaggtttta ctacgtaggc gaagttggtc tcgaactcct    120

gacctcagat gatccacccg cctcagcctc ccaaagtgct gggattacag gcgtgagcca    180

ccgcacctgg cctgtttatt ctcttaagag agaaaatgag gggattagtg gactgtagtt    240

ctggacaagg tggaaaactc ttaaagtgga agtattgggg caagtgctct gacaggctag    300

gatggtgcag tcagtccctt cacccagaaa tcagtagaat gttaacagtt cagactcaaa    360

ccttgtgaaa aacaggttct agaaaggaaa tccctcacag caactggcac cataatcaag    420

acagaatttt tgcagaataa atagagttac ctgctttcag ccccaggtcg tagctattgt    480

ctgccctgct gatatgtgat aataatttgt gatcctgttg tcttaaaatg gggtcactca    540

tctccagtag aattaagtcc acagtgaagt tgtcccccca tccccagaga taaacatata    600

tgaatgaact tacgtgataa caactactgc tgcctgggat catgagagac ctgaactgaa    660

ctgataggaa gtgaaaggtg gctgaggtaa tgagaataga cccatctgca gaggatcata    720

aaaccagcaa agacaagatc ttgtctaaga tgccttcaca aactttgtcc atgagaactg    780

taaggtcttc tccagacctg ttggctgctg ctgtgatctc tgcccaagag gagcttctga    840

ccaacatcca aagggcttct ggacccactg gactcctctg gaggtacctt ggtctcccga    900

tccatggctg tgttttttta ctccctttat cgc                                 933


<210>  6789
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  6789

Met Leu Glu Phe Cys Gly Thr Val Leu Ala His Cys Asn Leu Cys Leu 
1               5                   10                  15


Pro Glu Thr Arg Phe Tyr Tyr Val Gly Glu Val Gly Leu Glu Leu Leu 
            20                  25                  30


Thr Ser Asp Asp Pro Pro Ala Ser Ala Ser Gln Ser Ala Gly Ile Thr 
        35                  40                  45


Gly Val Ser His Arg Thr Trp Pro Val Tyr Ser Leu Lys Arg Glu Asn 
    50                  55                  60


Glu Gly Ile Ser Gly Leu 
65                  70


<210>  6790
<211>  2120
<212>  DNA
<213>  Homo sapiens

<400>  6790
gactcacagg acactaaggc tccttttctg aagaagcctt ttaccagtct catttagggg     60

atgggaacaa catgtcttca cctagggact ttagagcaga gcctgtaaac gattatgagg    120

gaaatgactc tgaagcagaa gacttgaatt tcagggagac tttgccttca tcaagtcagg    180

aaaacacacc tagatcaaag gtttttgaaa ataaagttaa ttcagagaag gtaaaacttt    240

ctcttcggaa tttcccacat aatgattatg aggatgtttt tgaagagcct tcagaaagtg    300

gcagtgatcc cagcatgtgg acagccagag gccccttcag aagagacagg tggagcagtg    360

aggatgagga ggctgcaggg ccatcacagg ctctctcccc tctactttct gttcaacatc    420

atggatatag tggcccaaat gagagaacaa cgttctggca tggttcaaac gaaggagcag    480

tatcactttt gttacgatat tgtgcttgaa gttcttcgga aacttctgac tttggattaa    540

gaaagacttc tgttgcctct cacttgaaat taccaagtgg gtttgcacct cctcataaag    600

aacatgtttg cactgtgctg aagggctttg ctatgcatac aatctgcttt cttggtttat    660

cagtttattt tctttctaaa agctccctga agggcaatat catttggctt ggggtgatca    720

gtgtttactt attgatcttg ctagacaata tcaaaataac ttcccacatt ttccagtgaa    780

acagatgtta cataaaacga ttgcagcttg gctatttggt tgaagggatt acagagccca    840

ataaaggatt taaaatatat tcattaagat tttatttgga aaggtggctg gagagagctg    900

aggatttcca ggactttgta agttcttatt ctgggagaac ataaggccaa taatcatgac    960

ctcttccagg catttttaag acagatgtct attcatgttc tttagctaga gcctgtactt   1020

tttgctggca tttgaataac ccagtttaaa aagagtccag ttagggtgga ctaactttgg   1080

acacaaattg gcttccattt cctacatttt catactgctg ccttcctaca gctgctagac   1140

caagacctgt tggtctggga agcatttcat ggatagggag agctcctctc ggtgaacagt   1200

ccaaaactaa aatagatgtt tatatagaaa gcccaagagg agatttttgc catgcctgag   1260

ttctttccta tcccacccta acacttaaca tattacttag tctgctttgt taaaagcaag   1320

tattaccttt aacttgcctc ttactctttg ccctttagct aactaataaa gtttgatata   1380

ggcattatta tataattctg agtcattcat ggtatatctc atgtttgatg tatttttcaa   1440

actaagatct atgatagttt tttttccaga gttccattaa atcatttatt tcctttactt   1500

tctcacctct gttgaaacat ttagaaactg gatttgggaa cccaattttg gaaaaccaga   1560

ttcatagtca tgaaaatgga aacttccata ttctgttttt gaaaagatgt ggccattatt   1620

acagtaattt tattatagga ctttgcctcg tacaattaat agtgatattt tggacaagga   1680

gttctggtga caagctatac ctaattataa gctataaaac aatagatatg agtgtttgta   1740

cagtttaact caatggagat cagaatattc tatgtattga gaaaatgttt aatatcaatc   1800

tataaatctt gaatttctaa gaggcttatt ttgttctttt ggctgaatga gtatatttga   1860

attggttgaa taattaataa ttctcattgt aaaaataatt atatgccaaa aatatatttg   1920

atgttaaatc aaatagatga ttctgtttac attgttcata tgaataataa tctgtgttaa   1980

tttcattttg ataattggcc tttaatattt gtatctctaa ttttattttc tctctgttac   2040

tgtaaaataa tagctataat gtataacaat tttcttcaga agaattctat gctattatta   2100

aaataaaata tttactgtgt                                               2120


<210>  6791
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  6791

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Val Gln His His Gly Tyr Ser Gly Pro Asn Glu Arg Thr Thr Phe 
        115                 120                 125


Trp His Gly Ser Asn Glu Gly Ala Val Ser Leu Leu Leu Arg Tyr Cys 
    130                 135                 140


Ala 
145


<210>  6792
<211>  2161
<212>  DNA
<213>  Homo sapiens

<400>  6792
gactcacagg acactaaggc tccttttctg aagaagcctt ttaccagtct catttagggg     60

atgggaacaa catgtcttca cctagggact ttagagcaga gcctgtgttt tctatttgat    120

cagtttttcc ccccgccttt gttcagtaaa cgattatgag ggaaatgact ctgaagcaga    180

agacttgaat ttcagggaga ctttgccttc atcaagtcag gaaaacacac ctagatcaaa    240

ggtttttgaa aataaagtta attcagagaa ggtaaaactt tctcttcgga atttcccaca    300

taatgattat gaggatgttt ttgaagagcc ttcagaaagt ggcagtgatc ccagcatgtg    360

gacagccaga ggccccttca gaagagacag gtggagcagt gaggatgagg aggctgcagg    420

gccatcacag gctctctccc ctctactttc tgttcaacat catggatata gtggcccaaa    480

tgagagaaca acgttctggc atggttcaaa cgaaggagca gtatcacttt tgttacgata    540

ttgtgcttga agttcttcgg aaacttctga ctttggatta agaaagactt ctgttgcctc    600

tcacttgaaa ttaccaagtg ggtttgcacc tcctcataaa gaacatgttt gcactgtgct    660

gaagggcttt gctatgcata caatctgctt tcttggttta tcagtttatt ttctttctaa    720

aagctccctg aagggcaata tcatttggct tggggtgatc agtgtttact tattgatctt    780

gctagacaat atcaaaataa cttcccacat tttccagtga aacagatgtt acataaaacg    840

attgcagctt ggctatttgg ttgaagggat tacagagccc aataaaggat ttaaaatata    900

ttcattaaga ttttatttgg aaaggtggct ggagagagct gaggatttcc aggactttgt    960

aagttcttat tctgggagaa cataaggcca ataatcatga cctcttccag gcatttttaa   1020

gacagatgtc tattcatgtt ctttagctag agcctgtact ttttgctggc atttgaataa   1080

cccagtttaa aaagagtcca gttagggtgg actaactttg gacacaaatt ggcttccatt   1140

tcctacattt tcatactgct gccttcctac agctgctaga ccaagacctg ttggtctggg   1200

aagcatttca tggataggga gagctcctct cggtgaacag tccaaaacta aaatagatgt   1260

ttatatagaa agcccaagag gagatttttg ccatgcctga gttctttcct atcccaccct   1320

aacacttaac atattactta gtctgctttg ttaaaagcaa gtattacctt taacttgcct   1380

cttactcttt gccctttagc taactaataa agtttgatat aggcattatt atataattct   1440

gagtcattca tggtatatct catgtttgat gtatttttca aactaagatc tatgatagtt   1500

ttttttccag agttccatta aatcatttat ttcctttact ttctcacctc tgttgaaaca   1560

tttagaaact ggatttggga acccaatttt ggaaaaccag attcatagtc atgaaaatgg   1620

aaacttccat attctgtttt tgaaaagatg tggccattat tacagtaatt ttattatagg   1680

actttgcctc gtacaattaa tagtgatatt ttggacaagg agttctggtg acaagctata   1740

cctaattata agctataaaa caatagatat gagtgtttgt acagtttaac tcaatggaga   1800

tcagaatatt ctatgtattg agaaaatgtt taatatcaat ctataaatct tgaatttcta   1860

agaggcttat tttgttcttt tggctgaatg agtatatttg aattggttga ataattaata   1920

attctcattg taaaaataat tatatgccaa aaatatattt gatgttaaat caaatagatg   1980

attctgttta cattgttcat atgaataata atctgtgtta atttcatttt gataattggc   2040

ctttaatatt tgtatctcta attttatttt ctctctgtta ctgtaaaata atagctataa   2100

tgtataacaa ttttcttcag aagaattcta tgctattatt aaaataaaat atttactgtg   2160

t                                                                   2161


<210>  6793
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6793

Met Ile Met Arg Met Phe Leu Lys Ser Leu Gln Lys Val Ala Val Ile 
1               5                   10                  15


Pro Ala Cys Gly Gln Pro Glu Ala Pro Ser Glu Glu Thr Gly Gly Ala 
            20                  25                  30


Val Arg Met Arg Arg Leu Gln Gly His His Arg Leu Ser Pro Leu Tyr 
        35                  40                  45


Phe Leu Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg 
    50                  55                  60


Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile 
65                  70                  75                  80


Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
                85                  90


<210>  6794
<211>  2274
<212>  DNA
<213>  Homo sapiens

<400>  6794
tggcctgact cacaggacac taaggctcct tttctgaaga agccttttac cagtctcatt     60

taggggatgg gaacaacatg tcttcaccta gggactttag agcagagcct ggtttttgaa    120

aataaagtta attcagagaa ggtaaaactt tctcttcgga atttcccaca taatgattat    180

gaggatgttt ttgaagagcc ttcagaaagt ggcagtgatc ccagcatgtg gacagccaga    240

ggccccttca gaagagacag gtggagcagt gaggatgagg aggctgcagg gccatcacag    300

gctctctccc ctctactttc tgatacgcgc aaaattgttt ctgaaggaga actagatcag    360

ttggctcaga ttcggccatt aatattcaat tttcatgagc agacagccat caaggattgt    420

ttgaaaatcc ttgaggaaaa aacagcagcg tatgatatca tgcaggaatt tatggcttta    480

gaacttaaga atctgcctgg tgagttcaac tctgggaatc aaccaagcaa cagagaaaaa    540

aacagatacc gagatattct tccatttcaa catcatggat atagtggccc aaatgagaga    600

acaacgttct ggcatggttc aaacgaagga gcagtatcac ttttgttacg atattgtgct    660

tgaagttctt cggaaacttc tgactttgga ttaagaaaga cttctgttgc ctctcacttg    720

aaattaccaa gtgggtttgc acctcctcat aaagaacatg tttgcactgt gctgaagggc    780

tttgctatgc atacaatctg ctttcttggt ttatcagttt attttctttc taaaagctcc    840

ctgaagggca atatcatttg gcttggggtg atcagtgttt acttattgat cttgctagac    900

aatatcaaaa taacttccca cattttccag tgaaacagat gttacataaa acgattgcag    960

cttggctatt tggttgaagg gattacagag cccaataaag gatttaaaat atattcatta   1020

agattttatt tggaaaggtg gctggagaga gctgaggatt tccaggactt tgtaagttct   1080

tattctggga gaacataagg ccaataatca tgacctcttc caggcatttt taagacagat   1140

gtctattcat gttctttagc tagagcctgt actttttgct ggcatttgaa taacccagtt   1200

taaaaagagt ccagttaggg tggactaact ttggacacaa attggcttcc atttcctaca   1260

ttttcatact gctgccttcc tacagctgct agaccaagac ctgttggtct gggaagcatt   1320

tcatggatag ggagagctcc tctcggtgaa cagtccaaaa ctaaaataga tgtttatata   1380

gaaagcccaa gaggagattt ttgccatgcc tgagttcttt cctatcccac cctaacactt   1440

aacatattac ttagtctgct ttgttaaaag caagtattac ctttaacttg cctcttactc   1500

tttgcccttt agctaactaa taaagtttga tataggcatt attatataat tctgagtcat   1560

tcatggtata tctcatgttt gatgtatttt tcaaactaag atctatgata gttttttttc   1620

cagagttcca ttaaatcatt tatttccttt actttctcac ctctgttgaa acatttagaa   1680

actggatttg ggaacccaat tttggaaaac cagattcata gtcatgaaaa tggaaacttc   1740

catattctgt ttttgaaaag atgtggccat tattacagta attttattat aggactttgc   1800

ctcgtacaat taatagtgat attttggaca aggagttctg gtgacaagct atacctaatt   1860

ataagctata aaacaataga tatgagtgtt tgtacagttt aactcaatgg agatcagaat   1920

attctatgta ttgagaaaat gtttaatatc aatctataaa tcttgaattt ctaagaggct   1980

tattttgttc ttttggctga atgagtatat ttgaattggt tgaataatta ataattctca   2040

ttgtaaaaat aattatatgc caaaaatata tttgatgtta aatcaaatag atgattctgt   2100

ttacattgtt catatgaata ataatctgtg ttaatttcat tttgataatt ggcctttaat   2160

atttgtatct ctaattttat tttctctctg ttactgtaaa ataatagcta taatgtataa   2220

caattttctt cagaagaatt ctatgctatt attaaaataa aatatttact gtgt         2274


<210>  6795
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  6795

Met Gly Thr Thr Cys Leu His Leu Gly Thr Leu Glu Gln Ser Leu Val 
1               5                   10                  15


Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn 
            20                  25                  30


Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser 
        35                  40                  45


Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp 
    50                  55                  60


Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu 
65                  70                  75                  80


Ser Pro Leu Leu Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu 
                85                  90                  95


Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln 
            100                 105                 110


Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala 
        115                 120                 125


Tyr Asp Ile Met Gln Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro 
    130                 135                 140


Gly Glu Phe Asn Ser Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg 
145                 150                 155                 160


Tyr Arg Asp Ile Leu Pro Phe Gln His His Gly Tyr Ser Gly Pro Asn 
                165                 170                 175


Glu Arg Thr Thr Phe Trp His Gly Ser Asn Glu Gly Ala Val Ser Leu 
            180                 185                 190


Leu Leu Arg Tyr Cys Ala 
        195


<210>  6796
<211>  1976
<212>  DNA
<213>  Homo sapiens

<400>  6796
ctctgtggta ggggaatgcc accaactccc tgaggagcag ccgtgtggta tgattggttt     60

ttgaaaataa agttaattca gagaaggtaa aactttctct tcggaatttc ccacataatg    120

attatgagga tgtttttgaa gagccttcag aaagtggcag tgatcccagc atgtggacag    180

ccagaggccc cttcagaaga gacaggtgga gcagtgagga tgaggaggct gcagggccat    240

cacaggctct ctcccctcta ctttctgttc aacatcatgg atatagtggc ccaaatgaga    300

gaacaacgtt ctggcatggt tcaaacgaag gagcagtatc acttttgtta cgatattgtg    360

cttgaagttc ttcggaaact tctgactttg gattaagaaa gacttctgtt gcctctcact    420

tgaaattacc aagtgggttt gcacctcctc ataaagaaca tgtttgcact gtgctgaagg    480

gctttgctat gcatacaatc tgctttcttg gtttatcagt ttattttctt tctaaaagct    540

ccctgaaggg caatatcatt tggcttgggg tgatcagtgt ttacttattg atcttgctag    600

acaatatcaa aataacttcc cacattttcc agtgaaacag atgttacata aaacgattgc    660

agcttggcta tttggttgaa gggattacag agcccaataa aggatttaaa atatattcat    720

taagatttta tttggaaagg tggctggaga gagctgagga tttccaggac tttgtaagtt    780

cttattctgg gagaacataa ggccaataat catgacctct tccaggcatt tttaagacag    840

atgtctattc atgttcttta gctagagcct gtactttttg ctggcatttg aataacccag    900

tttaaaaaga gtccagttag ggtggactaa ctttggacac aaattggctt ccatttccta    960

cattttcata ctgctgcctt cctacagctg ctagaccaag acctgttggt ctgggaagca   1020

tttcatggat agggagagct cctctcggtg aacagtccaa aactaaaata gatgtttata   1080

tagaaagccc aagaggagat ttttgccatg cctgagttct ttcctatccc accctaacac   1140

ttaacatatt acttagtctg ctttgttaaa agcaagtatt acctttaact tgcctcttac   1200

tctttgccct ttagctaact aataaagttt gatataggca ttattatata attctgagtc   1260

attcatggta tatctcatgt ttgatgtatt tttcaaacta agatctatga tagttttttt   1320

tccagagttc cattaaatca tttatttcct ttactttctc acctctgttg aaacatttag   1380

aaactggatt tgggaaccca attttggaaa accagattca tagtcatgaa aatggaaact   1440

tccatattct gtttttgaaa agatgtggcc attattacag taattttatt ataggacttt   1500

gcctcgtaca attaatagtg atattttgga caaggagttc tggtgacaag ctatacctaa   1560

ttataagcta taaaacaata gatatgagtg tttgtacagt ttaactcaat ggagatcaga   1620

atattctatg tattgagaaa atgtttaata tcaatctata aatcttgaat ttctaagagg   1680

cttattttgt tcttttggct gaatgagtat atttgaattg gttgaataat taataattct   1740

cattgtaaaa ataattatat gccaaaaata tatttgatgt taaatcaaat agatgattct   1800

gtttacattg ttcatatgaa taataatctg tgttaatttc attttgataa ttggccttta   1860

atatttgtat ctctaatttt attttctctc tgttactgta aaataatagc tataatgtat   1920

aacaattttc ttcagaagaa ttctatgcta ttattaaaat aaaatattta ctgtgt       1976


<210>  6797
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6797

Met Ile Met Arg Met Phe Leu Lys Ser Leu Gln Lys Val Ala Val Ile 
1               5                   10                  15


Pro Ala Cys Gly Gln Pro Glu Ala Pro Ser Glu Glu Thr Gly Gly Ala 
            20                  25                  30


Val Arg Met Arg Arg Leu Gln Gly His His Arg Leu Ser Pro Leu Tyr 
        35                  40                  45


Phe Leu Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg 
    50                  55                  60


Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile 
65                  70                  75                  80


Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
                85                  90


<210>  6798
<211>  2322
<212>  DNA
<213>  Homo sapiens

<400>  6798
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tgatgattca acacgcgttc ctcttggaaa aagcaaggac tacatcaatg ctagttatat    120

tagaatagtc aattgtggag aagagtattt ttatatcgct actcaaggac cactgctgag    180

caccatagat gacttttggc aaatggtgtt ggaaaataat tcaaatgtta ttgccatgat    240

aaccagagag atagaaggtg gaattatcaa atgctaccat tactggccca tttctctgaa    300

gaagccattg gaattgaaac acttccgtgt attcctggag aactaccaga tacttcaata    360

tttcatcatt cgaatgtttc aagttgtgga gaagtccacg ggaactagtc actctgtaaa    420

acagttgcag ttcaccaagt ggccagacca tggcactcct gcctcagcag atagcttcat    480

aaaatatatt cgttatgcaa ggaagagcca ccttacagga cccatggttg ttcactgcag    540

tgccggcata ggccggacag gggtgttcct atgtgtggat gtcgtgttct gtgccatcgt    600

aaagaactgt tcattcaaca tcatggatat agtggcccaa atgagagaac aacgttctgg    660

catggttcaa acgaaggagc agtatcactt ttgttacgat attgtgcttg aagttcttcg    720

gaaacttctg actttggatt aagaaagact tctgttgcct ctcacttgaa attaccaagt    780

gggtttgcac ctcctcataa agaacatgtt tgcactgtgc tgaagggctt tgctatgcat    840

acaatctgct ttcttggttt atcagtttat tttctttcta aaagctccct gaagggcaat    900

atcatttggc ttggggtgat cagtgtttac ttattgatct tgctagacaa tatcaaaata    960

acttcccaca ttttccagtg aaacagatgt tacataaaac gattgcagct tggctatttg   1020

gttgaaggga ttacagagcc caataaagga tttaaaatat attcattaag attttatttg   1080

gaaaggtggc tggagagagc tgaggatttc caggactttg taagttctta ttctgggaga   1140

acataaggcc aataatcatg acctcttcca ggcattttta agacagatgt ctattcatgt   1200

tctttagcta gagcctgtac tttttgctgg catttgaata acccagttta aaaagagtcc   1260

agttagggtg gactaacttt ggacacaaat tggcttccat ttcctacatt ttcatactgc   1320

tgccttccta cagctgctag accaagacct gttggtctgg gaagcatttc atggataggg   1380

agagctcctc tcggtgaaca gtccaaaact aaaatagatg tttatataga aagcccaaga   1440

ggagattttt gccatgcctg agttctttcc tatcccaccc taacacttaa catattactt   1500

agtctgcttt gttaaaagca agtattacct ttaacttgcc tcttactctt tgccctttag   1560

ctaactaata aagtttgata taggcattat tatataattc tgagtcattc atggtatatc   1620

tcatgtttga tgtatttttc aaactaagat ctatgatagt tttttttcca gagttccatt   1680

aaatcattta tttcctttac tttctcacct ctgttgaaac atttagaaac tggatttggg   1740

aacccaattt tggaaaacca gattcatagt catgaaaatg gaaacttcca tattctgttt   1800

ttgaaaagat gtggccatta ttacagtaat tttattatag gactttgcct cgtacaatta   1860

atagtgatat tttggacaag gagttctggt gacaagctat acctaattat aagctataaa   1920

acaatagata tgagtgtttg tacagtttaa ctcaatggag atcagaatat tctatgtatt   1980

gagaaaatgt ttaatatcaa tctataaatc ttgaatttct aagaggctta ttttgttctt   2040

ttggctgaat gagtatattt gaattggttg aataattaat aattctcatt gtaaaaataa   2100

ttatatgcca aaaatatatt tgatgttaaa tcaaatagat gattctgttt acattgttca   2160

tatgaataat aatctgtgtt aatttcattt tgataattgg cctttaatat ttgtatctct   2220

aattttattt tctctctgtt actgtaaaat aatagctata atgtataaca attttcttca   2280

gaagaattct atgctattat taaaataaaa tatttactgt gt                      2322


<210>  6799
<211>  228
<212>  PRT
<213>  Homo sapiens

<400>  6799

Met Ile Asp Asp Ser Thr Arg Val Pro Leu Gly Lys Ser Lys Asp Tyr 
1               5                   10                  15


Ile Asn Ala Ser Tyr Ile Arg Ile Val Asn Cys Gly Glu Glu Tyr Phe 
            20                  25                  30


Tyr Ile Ala Thr Gln Gly Pro Leu Leu Ser Thr Ile Asp Asp Phe Trp 
        35                  40                  45


Gln Met Val Leu Glu Asn Asn Ser Asn Val Ile Ala Met Ile Thr Arg 
    50                  55                  60


Glu Ile Glu Gly Gly Ile Ile Lys Cys Tyr His Tyr Trp Pro Ile Ser 
65                  70                  75                  80


Leu Lys Lys Pro Leu Glu Leu Lys His Phe Arg Val Phe Leu Glu Asn 
                85                  90                  95


Tyr Gln Ile Leu Gln Tyr Phe Ile Ile Arg Met Phe Gln Val Val Glu 
            100                 105                 110


Lys Ser Thr Gly Thr Ser His Ser Val Lys Gln Leu Gln Phe Thr Lys 
        115                 120                 125


Trp Pro Asp His Gly Thr Pro Ala Ser Ala Asp Ser Phe Ile Lys Tyr 
    130                 135                 140


Ile Arg Tyr Ala Arg Lys Ser His Leu Thr Gly Pro Met Val Val His 
145                 150                 155                 160


Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Phe Leu Cys Val Asp Val 
                165                 170                 175


Val Phe Cys Ala Ile Val Lys Asn Cys Ser Phe Asn Ile Met Asp Ile 
            180                 185                 190


Val Ala Gln Met Arg Glu Gln Arg Ser Gly Met Val Gln Thr Lys Glu 
        195                 200                 205


Gln Tyr His Phe Cys Tyr Asp Ile Val Leu Glu Val Leu Arg Lys Leu 
    210                 215                 220


Leu Thr Leu Asp 
225


<210>  6800
<211>  2225
<212>  DNA
<213>  Homo sapiens

<400>  6800
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tggtttttga aaataaagtt aattcagaga aggtaaaact ttctcttcgg aatttcccac    120

ataatgatta tgaggatgtt tttgaagagc cttcagaaag tggcagtgat cccagcatgt    180

ggacagccag aggccccttc agaagagaca ggtggagcag tgaggatgag gaggctgcag    240

ggccatcaca ggctctctcc cctctacttt ctgatacgcg caaaattgtt tctgaaggag    300

aactagatca gttggctcag attcggccat taatattcaa ttttcatgag cagacagcca    360

tcaaggattg tttgaaaatc cttgaggaaa aaacagcagc gtatgatatc atgcaggaat    420

ttatggcttt agaacttaag aatctgcctg gtgagttcaa ctctgggaat caaccaagca    480

acagagaaaa aaacagatac cgagatattc ttccatttca acatcatgga tatagtggcc    540

caaatgagag aacaacgttc tggcatggtt caaacgaagg agcagtatca cttttgttac    600

gatattgtgc ttgaagttct tcggaaactt ctgactttgg attaagaaag acttctgttg    660

cctctcactt gaaattacca agtgggtttg cacctcctca taaagaacat gtttgcactg    720

tgctgaaggg ctttgctatg catacaatct gctttcttgg tttatcagtt tattttcttt    780

ctaaaagctc cctgaagggc aatatcattt ggcttggggt gatcagtgtt tacttattga    840

tcttgctaga caatatcaaa ataacttccc acattttcca gtgaaacaga tgttacataa    900

aacgattgca gcttggctat ttggttgaag ggattacaga gcccaataaa ggatttaaaa    960

tatattcatt aagattttat ttggaaaggt ggctggagag agctgaggat ttccaggact   1020

ttgtaagttc ttattctggg agaacataag gccaataatc atgacctctt ccaggcattt   1080

ttaagacaga tgtctattca tgttctttag ctagagcctg tactttttgc tggcatttga   1140

ataacccagt ttaaaaagag tccagttagg gtggactaac tttggacaca aattggcttc   1200

catttcctac attttcatac tgctgccttc ctacagctgc tagaccaaga cctgttggtc   1260

tgggaagcat ttcatggata gggagagctc ctctcggtga acagtccaaa actaaaatag   1320

atgtttatat agaaagccca agaggagatt tttgccatgc ctgagttctt tcctatccca   1380

ccctaacact taacatatta cttagtctgc tttgttaaaa gcaagtatta cctttaactt   1440

gcctcttact ctttgccctt tagctaacta ataaagtttg atataggcat tattatataa   1500

ttctgagtca ttcatggtat atctcatgtt tgatgtattt ttcaaactaa gatctatgat   1560

agtttttttt ccagagttcc attaaatcat ttatttcctt tactttctca cctctgttga   1620

aacatttaga aactggattt gggaacccaa ttttggaaaa ccagattcat agtcatgaaa   1680

atggaaactt ccatattctg tttttgaaaa gatgtggcca ttattacagt aattttatta   1740

taggactttg cctcgtacaa ttaatagtga tattttggac aaggagttct ggtgacaagc   1800

tatacctaat tataagctat aaaacaatag atatgagtgt ttgtacagtt taactcaatg   1860

gagatcagaa tattctatgt attgagaaaa tgtttaatat caatctataa atcttgaatt   1920

tctaagaggc ttattttgtt cttttggctg aatgagtata tttgaattgg ttgaataatt   1980

aataattctc attgtaaaaa taattatatg ccaaaaatat atttgatgtt aaatcaaata   2040

gatgattctg tttacattgt tcatatgaat aataatctgt gttaatttca ttttgataat   2100

tggcctttaa tatttgtatc tctaatttta ttttctctct gttactgtaa aataatagct   2160

ataatgtata acaattttct tcagaagaat tctatgctat tattaaaata aaatatttac   2220

tgtgt                                                               2225


<210>  6801
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  6801

Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser Glu 
1               5                   10                  15


Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu Ser 
            20                  25                  30


Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala Gln 
        35                  40                  45


Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys Asp 
    50                  55                  60


Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met Gln 
65                  70                  75                  80


Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro Gly Glu Phe Asn Ser 
                85                  90                  95


Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg Tyr Arg Asp Ile Leu 
            100                 105                 110


Pro Phe Gln His His Gly Tyr Ser Gly Pro Asn Glu Arg Thr Thr Phe 
        115                 120                 125


Trp His Gly Ser Asn Glu Gly Ala Val Ser Leu Leu Leu Arg Tyr Cys 
    130                 135                 140


Ala 
145


<210>  6802
<211>  2933
<212>  DNA
<213>  Homo sapiens

<400>  6802
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgg tttttgaaaa taaagttaat    240

tcagagaagg taaaactttc tcttcggaat ttcccacata atgattatga ggatgttttt    300

gaagagcctt cagaaagtgg cagtgatccc agcatgtgga cagccagagg ccccttcaga    360

agagacaggt ggagcagtga ggatgaggag gctgcagggc catcacaggc tctctcccct    420

ctactttctg atacgcgcaa aattgtttct gaaggagaac tagatcagtt ggctcagatt    480

cggccattaa tattcaattt tcatgagcag acagccatca aggattgttt gaaaatcctt    540

gaggaaaaaa cagcagcgta tgatatcatg caggaattta tggctttaga acttaagaat    600

ctgcctggtg agttcaactc tgggaatcaa ccaagcaaca gagaaaaaaa cagataccga    660

gatattcttc catatgattc aacacgcgtt cctcttggaa aaagcaagga ctacatcaat    720

gctagttata ttagaatagt caattgtgga gaagagtatt tttatatcgc tactcaagga    780

ccactgctga gcaccataga tgacttttgg caaatggtgt tggaaaataa ttcaaatgtt    840

attgccatga taaccagaga gatagaaggt ggaattatca aatgctacca ttactggccc    900

atttctctga agaagccatt ggaattgaaa cacttccgtg tattcctgga gaactaccag    960

atacttcaat atttcatcat tcgaatgttt caagttgtgg agaagtccac gggaactagt   1020

cactctgtaa aacagttgca gttcaccaag tggccagacc atggcactcc tgcctcagca   1080

gatagcttca taaaatatat tcgttatgca aggaagagcc accttacagg acccatggtt   1140

gttcactgca gtgccggcat aggccggaca ggggtgttcc tatgtgtgga tgtcgtgttc   1200

tgtgccatcg taaagaactg ttcattcaac atcatggata tagtggccca aatgagagaa   1260

caacgttctg gcatggttca aacgaaggag cagtatcact tttgttacga tattgtgctt   1320

gaagttcttc ggaaacttct gactttggat taagaaagac ttctgttgcc tctcacttga   1380

aattaccaag tgggtttgca cctcctcata aagaacatgt ttgcactgtg ctgaagggct   1440

ttgctatgca tacaatctgc tttcttggtt tatcagttta ttttctttct aaaagctccc   1500

tgaagggcaa tatcatttgg cttggggtga tcagtgttta cttattgatc ttgctagaca   1560

atatcaaaat aacttcccac attttccagt gaaacagatg ttacataaaa cgattgcagc   1620

ttggctattt ggttgaaggg attacagagc ccaataaagg atttaaaata tattcattaa   1680

gattttattt ggaaaggtgg ctggagagag ctgaggattt ccaggacttt gtaagttctt   1740

attctgggag aacataaggc caataatcat gacctcttcc aggcattttt aagacagatg   1800

tctattcatg ttctttagct agagcctgta ctttttgctg gcatttgaat aacccagttt   1860

aaaaagagtc cagttagggt ggactaactt tggacacaaa ttggcttcca tttcctacat   1920

tttcatactg ctgccttcct acagctgcta gaccaagacc tgttggtctg ggaagcattt   1980

catggatagg gagagctcct ctcggtgaac agtccaaaac taaaatagat gtttatatag   2040

aaagcccaag aggagatttt tgccatgcct gagttctttc ctatcccacc ctaacactta   2100

acatattact tagtctgctt tgttaaaagc aagtattacc tttaacttgc ctcttactct   2160

ttgcccttta gctaactaat aaagtttgat ataggcatta ttatataatt ctgagtcatt   2220

catggtatat ctcatgtttg atgtattttt caaactaaga tctatgatag ttttttttcc   2280

agagttccat taaatcattt atttccttta ctttctcacc tctgttgaaa catttagaaa   2340

ctggatttgg gaacccaatt ttggaaaacc agattcatag tcatgaaaat ggaaacttcc   2400

atattctgtt tttgaaaaga tgtggccatt attacagtaa ttttattata ggactttgcc   2460

tcgtacaatt aatagtgata ttttggacaa ggagttctgg tgacaagcta tacctaatta   2520

taagctataa aacaatagat atgagtgttt gtacagttta actcaatgga gatcagaata   2580

ttctatgtat tgagaaaatg tttaatatca atctataaat cttgaatttc taagaggctt   2640

attttgttct tttggctgaa tgagtatatt tgaattggtt gaataattaa taattctcat   2700

tgtaaaaata attatatgcc aaaaatatat ttgatgttaa atcaaataga tgattctgtt   2760

tacattgttc atatgaataa taatctgtgt taatttcatt ttgataattg gcctttaata   2820

tttgtatctc taattttatt ttctctctgt tactgtaaaa taatagctat aatgtataac   2880

aattttcttc agaagaattc tatgctatta ttaaaataaa atatttactg tgt          2933


<210>  6803
<211>  392
<212>  PRT
<213>  Homo sapiens

<400>  6803

Met Gly Thr Thr Cys Leu His Leu Gly Thr Leu Glu Gln Ser Leu Val 
1               5                   10                  15


Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn 
            20                  25                  30


Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser 
        35                  40                  45


Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp 
    50                  55                  60


Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu 
65                  70                  75                  80


Ser Pro Leu Leu Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu 
                85                  90                  95


Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln 
            100                 105                 110


Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala 
        115                 120                 125


Tyr Asp Ile Met Gln Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro 
    130                 135                 140


Gly Glu Phe Asn Ser Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg 
145                 150                 155                 160


Tyr Arg Asp Ile Leu Pro Tyr Asp Ser Thr Arg Val Pro Leu Gly Lys 
                165                 170                 175


Ser Lys Asp Tyr Ile Asn Ala Ser Tyr Ile Arg Ile Val Asn Cys Gly 
            180                 185                 190


Glu Glu Tyr Phe Tyr Ile Ala Thr Gln Gly Pro Leu Leu Ser Thr Ile 
        195                 200                 205


Asp Asp Phe Trp Gln Met Val Leu Glu Asn Asn Ser Asn Val Ile Ala 
    210                 215                 220


Met Ile Thr Arg Glu Ile Glu Gly Gly Ile Ile Lys Cys Tyr His Tyr 
225                 230                 235                 240


Trp Pro Ile Ser Leu Lys Lys Pro Leu Glu Leu Lys His Phe Arg Val 
                245                 250                 255


Phe Leu Glu Asn Tyr Gln Ile Leu Gln Tyr Phe Ile Ile Arg Met Phe 
            260                 265                 270


Gln Val Val Glu Lys Ser Thr Gly Thr Ser His Ser Val Lys Gln Leu 
        275                 280                 285


Gln Phe Thr Lys Trp Pro Asp His Gly Thr Pro Ala Ser Ala Asp Ser 
    290                 295                 300


Phe Ile Lys Tyr Ile Arg Tyr Ala Arg Lys Ser His Leu Thr Gly Pro 
305                 310                 315                 320


Met Val Val His Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Phe Leu 
                325                 330                 335


Cys Val Asp Val Val Phe Cys Ala Ile Val Lys Asn Cys Ser Phe Asn 
            340                 345                 350


Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg Ser Gly Met Val 
        355                 360                 365


Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile Val Leu Glu Val 
    370                 375                 380


Leu Arg Lys Leu Leu Thr Leu Asp 
385                 390


<210>  6804
<211>  2350
<212>  DNA
<213>  Homo sapiens

<400>  6804
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tggtttttga aaataaagtt aattcagaga aggtaaaact ttctcttcgg aatttcccac    120

ataatgatta tgaggatgtt tttgaagagc cttcagaaag tggcagtgat cccagcatgt    180

ggacagccag aggccccttc agaagagaca ggtggagcag tgaggatgag gaggctgcag    240

ggccatcaca ggctctctcc cctctacttt ctgatacgcg caaaattgtt tctgaaggag    300

aactagatca gttggctcag attcggccat taatattcaa ttttcatgag cagacagcca    360

tcaaggattg tttgaaaatc cttgaggaaa aaacagcagc gtatgatatc atgcaggaat    420

ttatgacggg aactagtcac tctgtaaaac agttgcagtt caccaagtgg ccagaccatg    480

gcactcctgc ctcagcagat agcttcataa aatatattcg ttatgcaagg aagagccacc    540

ttacaggacc catggttgtt cactgcagtg ccggcatagg ccggacaggg gtgttcctat    600

gtgtggatgt cgtgttctgt gccatcgtaa agaactgttc attcaacatc atggatatag    660

tggcccaaat gagagaacaa cgttctggca tggttcaaac gaaggagcag tatcactttt    720

gttacgatat tgtgcttgaa gttcttcgga aacttctgac tttggattaa gaaagacttc    780

tgttgcctct cacttgaaat taccaagtgg gtttgcacct cctcataaag aacatgtttg    840

cactgtgctg aagggctttg ctatgcatac aatctgcttt cttggtttat cagtttattt    900

tctttctaaa agctccctga agggcaatat catttggctt ggggtgatca gtgtttactt    960

attgatcttg ctagacaata tcaaaataac ttcccacatt ttccagtgaa acagatgtta   1020

cataaaacga ttgcagcttg gctatttggt tgaagggatt acagagccca ataaaggatt   1080

taaaatatat tcattaagat tttatttgga aaggtggctg gagagagctg aggatttcca   1140

ggactttgta agttcttatt ctgggagaac ataaggccaa taatcatgac ctcttccagg   1200

catttttaag acagatgtct attcatgttc tttagctaga gcctgtactt tttgctggca   1260

tttgaataac ccagtttaaa aagagtccag ttagggtgga ctaactttgg acacaaattg   1320

gcttccattt cctacatttt catactgctg ccttcctaca gctgctagac caagacctgt   1380

tggtctggga agcatttcat ggatagggag agctcctctc ggtgaacagt ccaaaactaa   1440

aatagatgtt tatatagaaa gcccaagagg agatttttgc catgcctgag ttctttccta   1500

tcccacccta acacttaaca tattacttag tctgctttgt taaaagcaag tattaccttt   1560

aacttgcctc ttactctttg ccctttagct aactaataaa gtttgatata ggcattatta   1620

tataattctg agtcattcat ggtatatctc atgtttgatg tatttttcaa actaagatct   1680

atgatagttt tttttccaga gttccattaa atcatttatt tcctttactt tctcacctct   1740

gttgaaacat ttagaaactg gatttgggaa cccaattttg gaaaaccaga ttcatagtca   1800

tgaaaatgga aacttccata ttctgttttt gaaaagatgt ggccattatt acagtaattt   1860

tattatagga ctttgcctcg tacaattaat agtgatattt tggacaagga gttctggtga   1920

caagctatac ctaattataa gctataaaac aatagatatg agtgtttgta cagtttaact   1980

caatggagat cagaatattc tatgtattga gaaaatgttt aatatcaatc tataaatctt   2040

gaatttctaa gaggcttatt ttgttctttt ggctgaatga gtatatttga attggttgaa   2100

taattaataa ttctcattgt aaaaataatt atatgccaaa aatatatttg atgttaaatc   2160

aaatagatga ttctgtttac attgttcata tgaataataa tctgtgttaa tttcattttg   2220

ataattggcc tttaatattt gtatctctaa ttttattttc tctctgttac tgtaaaataa   2280

tagctataat gtataacaat tttcttcaga agaattctat gctattatta aaataaaata   2340

tttactgtgt                                                          2350


<210>  6805
<211>  197
<212>  PRT
<213>  Homo sapiens

<400>  6805

Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser Glu 
1               5                   10                  15


Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu Ser 
            20                  25                  30


Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala Gln 
        35                  40                  45


Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys Asp 
    50                  55                  60


Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met Gln 
65                  70                  75                  80


Glu Phe Met Thr Gly Thr Ser His Ser Val Lys Gln Leu Gln Phe Thr 
                85                  90                  95


Lys Trp Pro Asp His Gly Thr Pro Ala Ser Ala Asp Ser Phe Ile Lys 
            100                 105                 110


Tyr Ile Arg Tyr Ala Arg Lys Ser His Leu Thr Gly Pro Met Val Val 
        115                 120                 125


His Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Phe Leu Cys Val Asp 
    130                 135                 140


Val Val Phe Cys Ala Ile Val Lys Asn Cys Ser Phe Asn Ile Met Asp 
145                 150                 155                 160


Ile Val Ala Gln Met Arg Glu Gln Arg Ser Gly Met Val Gln Thr Lys 
                165                 170                 175


Glu Gln Tyr His Phe Cys Tyr Asp Ile Val Leu Glu Val Leu Arg Lys 
            180                 185                 190


Leu Leu Thr Leu Asp 
        195


<210>  6806
<211>  2386
<212>  DNA
<213>  Homo sapiens

<400>  6806
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgt aaacgattat gagggaaatg    240

actctgaagc agaagacttg aatttcaggg agactttgcc ttcatcaagt caggaaaaca    300

cacctagatc aaaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    360

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    420

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    480

aggaggctgc agggccatca caggctctct cccctctact ttctgatacg cgcaaaattg    540

tttctgaagg agaactagat cagttggctc agattcggcc attaatattc aattttcatg    600

agcagacagc catcaaggat tgtttgaaaa tccttgagga aaaaacagca gcgtatgata    660

tcatgcagga atttatgttc aacatcatgg atatagtggc ccaaatgaga gaacaacgtt    720

ctggcatggt tcaaacgaag gagcagtatc acttttgtta cgatattgtg cttgaagttc    780

ttcggaaact tctgactttg gattaagaaa gacttctgtt gcctctcact tgaaattacc    840

aagtgggttt gcacctcctc ataaagaaca tgtttgcact gtgctgaagg gctttgctat    900

gcatacaatc tgctttcttg gtttatcagt ttattttctt tctaaaagct ccctgaaggg    960

caatatcatt tggcttgggg tgatcagtgt ttacttattg atcttgctag acaatatcaa   1020

aataacttcc cacattttcc agtgaaacag atgttacata aaacgattgc agcttggcta   1080

tttggttgaa gggattacag agcccaataa aggatttaaa atatattcat taagatttta   1140

tttggaaagg tggctggaga gagctgagga tttccaggac tttgtaagtt cttattctgg   1200

gagaacataa ggccaataat catgacctct tccaggcatt tttaagacag atgtctattc   1260

atgttcttta gctagagcct gtactttttg ctggcatttg aataacccag tttaaaaaga   1320

gtccagttag ggtggactaa ctttggacac aaattggctt ccatttccta cattttcata   1380

ctgctgcctt cctacagctg ctagaccaag acctgttggt ctgggaagca tttcatggat   1440

agggagagct cctctcggtg aacagtccaa aactaaaata gatgtttata tagaaagccc   1500

aagaggagat ttttgccatg cctgagttct ttcctatccc accctaacac ttaacatatt   1560

acttagtctg ctttgttaaa agcaagtatt acctttaact tgcctcttac tctttgccct   1620

ttagctaact aataaagttt gatataggca ttattatata attctgagtc attcatggta   1680

tatctcatgt ttgatgtatt tttcaaacta agatctatga tagttttttt tccagagttc   1740

cattaaatca tttatttcct ttactttctc acctctgttg aaacatttag aaactggatt   1800

tgggaaccca attttggaaa accagattca tagtcatgaa aatggaaact tccatattct   1860

gtttttgaaa agatgtggcc attattacag taattttatt ataggacttt gcctcgtaca   1920

attaatagtg atattttgga caaggagttc tggtgacaag ctatacctaa ttataagcta   1980

taaaacaata gatatgagtg tttgtacagt ttaactcaat ggagatcaga atattctatg   2040

tattgagaaa atgtttaata tcaatctata aatcttgaat ttctaagagg cttattttgt   2100

tcttttggct gaatgagtat atttgaattg gttgaataat taataattct cattgtaaaa   2160

ataattatat gccaaaaata tatttgatgt taaatcaaat agatgattct gtttacattg   2220

ttcatatgaa taataatctg tgttaatttc attttgataa ttggccttta atatttgtat   2280

ctctaatttt attttctctc tgttactgta aaataatagc tataatgtat aacaattttc   2340

ttcagaagaa ttctatgcta ttattaaaat aaaatattta ctgtgt                  2386


<210>  6807
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  6807

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
        115                 120                 125


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
    130                 135                 140


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
145                 150                 155                 160


Gln Glu Phe Met Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu 
                165                 170                 175


Gln Arg Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr 
            180                 185                 190


Asp Ile Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
        195                 200                 205


<210>  6808
<211>  2118
<212>  DNA
<213>  Homo sapiens

<400>  6808
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tgtgttttct atttgatcag tttttccccc cgcctttgtt cagtaaacga ttatgaggga    120

aatgactctg aagcagaaga cttgaatttc agggagactt tgccttcatc aagtcaggaa    180

aacacaccta gatcaaaggt ttttgaaaat aaagttaatt cagagaaggt aaaactttct    240

cttcggaatt tcccacataa tgattatgag gatgtttttg aagagccttc agaaagtggc    300

agtgatccca gcatgtggac agccagaggc cccttcagaa gagacaggtg gagcagtgag    360

gatgaggagg ctgcagggcc atcacaggct ctctcccctc tactttctgt tcaacatcat    420

ggatatagtg gcccaaatga gagaacaacg ttctggcatg gttcaaacga aggagcagta    480

tcacttttgt tacgatattg tgcttgaagt tcttcggaaa cttctgactt tggattaaga    540

aagacttctg ttgcctctca cttgaaatta ccaagtgggt ttgcacctcc tcataaagaa    600

catgtttgca ctgtgctgaa gggctttgct atgcatacaa tctgctttct tggtttatca    660

gtttattttc tttctaaaag ctccctgaag ggcaatatca tttggcttgg ggtgatcagt    720

gtttacttat tgatcttgct agacaatatc aaaataactt cccacatttt ccagtgaaac    780

agatgttaca taaaacgatt gcagcttggc tatttggttg aagggattac agagcccaat    840

aaaggattta aaatatattc attaagattt tatttggaaa ggtggctgga gagagctgag    900

gatttccagg actttgtaag ttcttattct gggagaacat aaggccaata atcatgacct    960

cttccaggca tttttaagac agatgtctat tcatgttctt tagctagagc ctgtactttt   1020

tgctggcatt tgaataaccc agtttaaaaa gagtccagtt agggtggact aactttggac   1080

acaaattggc ttccatttcc tacattttca tactgctgcc ttcctacagc tgctagacca   1140

agacctgttg gtctgggaag catttcatgg atagggagag ctcctctcgg tgaacagtcc   1200

aaaactaaaa tagatgttta tatagaaagc ccaagaggag atttttgcca tgcctgagtt   1260

ctttcctatc ccaccctaac acttaacata ttacttagtc tgctttgtta aaagcaagta   1320

ttacctttaa cttgcctctt actctttgcc ctttagctaa ctaataaagt ttgatatagg   1380

cattattata taattctgag tcattcatgg tatatctcat gtttgatgta tttttcaaac   1440

taagatctat gatagttttt tttccagagt tccattaaat catttatttc ctttactttc   1500

tcacctctgt tgaaacattt agaaactgga tttgggaacc caattttgga aaaccagatt   1560

catagtcatg aaaatggaaa cttccatatt ctgtttttga aaagatgtgg ccattattac   1620

agtaatttta ttataggact ttgcctcgta caattaatag tgatattttg gacaaggagt   1680

tctggtgaca agctatacct aattataagc tataaaacaa tagatatgag tgtttgtaca   1740

gtttaactca atggagatca gaatattcta tgtattgaga aaatgtttaa tatcaatcta   1800

taaatcttga atttctaaga ggcttatttt gttcttttgg ctgaatgagt atatttgaat   1860

tggttgaata attaataatt ctcattgtaa aaataattat atgccaaaaa tatatttgat   1920

gttaaatcaa atagatgatt ctgtttacat tgttcatatg aataataatc tgtgttaatt   1980

tcattttgat aattggcctt taatatttgt atctctaatt ttattttctc tctgttactg   2040

taaaataata gctataatgt ataacaattt tcttcagaag aattctatgc tattattaaa   2100

ataaaatatt tactgtgt                                                 2118


<210>  6809
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6809

Met Ile Met Arg Met Phe Leu Lys Ser Leu Gln Lys Val Ala Val Ile 
1               5                   10                  15


Pro Ala Cys Gly Gln Pro Glu Ala Pro Ser Glu Glu Thr Gly Gly Ala 
            20                  25                  30


Val Arg Met Arg Arg Leu Gln Gly His His Arg Leu Ser Pro Leu Tyr 
        35                  40                  45


Phe Leu Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg 
    50                  55                  60


Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile 
65                  70                  75                  80


Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
                85                  90


<210>  6810
<211>  2477
<212>  DNA
<213>  Homo sapiens

<400>  6810
ctgtggctct gtggtagggg aatgccacca actccctgag gagcagccgt gtggtatgat     60

tggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgt aaacgattat gagggaaatg    240

actctgaagc agaagacttg aatttcaggg agactttgcc ttcatcaagt caggaaaaca    300

cacctagatc aaaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    360

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    420

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    480

aggaggctgc agggccatca caggctctct cccctctact ttctgatacg cgcaaaattg    540

tttctgaagg agaactagat cagttggctc agattcggcc attaatattc aattttcatg    600

agcagacagc catcaaggat tgtttgaaaa tccttgagga aaaaacagca gcgtatgata    660

tcatgcagga atttatggct ttagaactta agaatctgcc tggtgagttc aactctggga    720

atcaaccaag caacagagaa aaaaacagat accgagatat tcttccattt caacatcatg    780

gatatagtgg cccaaatgag agaacaacgt tctggcatgg ttcaaacgaa ggagcagtat    840

cacttttgtt acgatattgt gcttgaagtt cttcggaaac ttctgacttt ggattaagaa    900

agacttctgt tgcctctcac ttgaaattac caagtgggtt tgcacctcct cataaagaac    960

atgtttgcac tgtgctgaag ggctttgcta tgcatacaat ctgctttctt ggtttatcag   1020

tttattttct ttctaaaagc tccctgaagg gcaatatcat ttggcttggg gtgatcagtg   1080

tttacttatt gatcttgcta gacaatatca aaataacttc ccacattttc cagtgaaaca   1140

gatgttacat aaaacgattg cagcttggct atttggttga agggattaca gagcccaata   1200

aaggatttaa aatatattca ttaagatttt atttggaaag gtggctggag agagctgagg   1260

atttccagga ctttgtaagt tcttattctg ggagaacata aggccaataa tcatgacctc   1320

ttccaggcat ttttaagaca gatgtctatt catgttcttt agctagagcc tgtacttttt   1380

gctggcattt gaataaccca gtttaaaaag agtccagtta gggtggacta actttggaca   1440

caaattggct tccatttcct acattttcat actgctgcct tcctacagct gctagaccaa   1500

gacctgttgg tctgggaagc atttcatgga tagggagagc tcctctcggt gaacagtcca   1560

aaactaaaat agatgtttat atagaaagcc caagaggaga tttttgccat gcctgagttc   1620

tttcctatcc caccctaaca cttaacatat tacttagtct gctttgttaa aagcaagtat   1680

tacctttaac ttgcctctta ctctttgccc tttagctaac taataaagtt tgatataggc   1740

attattatat aattctgagt cattcatggt atatctcatg tttgatgtat ttttcaaact   1800

aagatctatg atagtttttt ttccagagtt ccattaaatc atttatttcc tttactttct   1860

cacctctgtt gaaacattta gaaactggat ttgggaaccc aattttggaa aaccagattc   1920

atagtcatga aaatggaaac ttccatattc tgtttttgaa aagatgtggc cattattaca   1980

gtaattttat tataggactt tgcctcgtac aattaatagt gatattttgg acaaggagtt   2040

ctggtgacaa gctataccta attataagct ataaaacaat agatatgagt gtttgtacag   2100

tttaactcaa tggagatcag aatattctat gtattgagaa aatgtttaat atcaatctat   2160

aaatcttgaa tttctaagag gcttattttg ttcttttggc tgaatgagta tatttgaatt   2220

ggttgaataa ttaataattc tcattgtaaa aataattata tgccaaaaat atatttgatg   2280

ttaaatcaaa tagatgattc tgtttacatt gttcatatga ataataatct gtgttaattt   2340

cattttgata attggccttt aatatttgta tctctaattt tattttctct ctgttactgt   2400

aaaataatag ctataatgta taacaatttt cttcagaaga attctatgct attattaaaa   2460

taaaatattt actgtgt                                                  2477


<210>  6811
<211>  226
<212>  PRT
<213>  Homo sapiens

<400>  6811

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
        115                 120                 125


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
    130                 135                 140


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
145                 150                 155                 160


Gln Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro Gly Glu Phe Asn 
                165                 170                 175


Ser Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg Tyr Arg Asp Ile 
            180                 185                 190


Leu Pro Phe Gln His His Gly Tyr Ser Gly Pro Asn Glu Arg Thr Thr 
        195                 200                 205


Phe Trp His Gly Ser Asn Glu Gly Ala Val Ser Leu Leu Leu Arg Tyr 
    210                 215                 220


Cys Ala 
225


<210>  6812
<211>  2136
<212>  DNA
<213>  Homo sapiens

<400>  6812
ccagctgcac tgtgacgcgt gttggggcgc ctatgcgaga cgggaccggg acaggaaccc     60

tgtggctctg tggtagggga atgccaccaa ctccctgagg agcagccgtg tggtatgatt    120

gtaaacgatt atgagggaaa tgactctgaa gcagaagact tgaatttcag ggagactttg    180

ccttcatcaa gtcaggaaaa cacacctaga tcaaaggttt ttgaaaataa agttaattca    240

gagaaggtaa aactttctct tcggaatttc ccacataatg attatgagga tgtttttgaa    300

gagccttcag aaagtggcag tgatcccagc atgtggacag ccagaggccc cttcagaaga    360

gacaggtgga gcagtgagga tgaggaggct gcagggccat cacaggctct ctcccctcta    420

ctttctgttc aacatcatgg atatagtggc ccaaatgaga gaacaacgtt ctggcatggt    480

tcaaacgaag gagcagtatc acttttgtta cgatattgtg cttgaagttc ttcggaaact    540

tctgactttg gattaagaaa gacttctgtt gcctctcact tgaaattacc aagtgggttt    600

gcacctcctc ataaagaaca tgtttgcact gtgctgaagg gctttgctat gcatacaatc    660

tgctttcttg gtttatcagt ttattttctt tctaaaagct ccctgaaggg caatatcatt    720

tggcttgggg tgatcagtgt ttacttattg atcttgctag acaatatcaa aataacttcc    780

cacattttcc agtgaaacag atgttacata aaacgattgc agcttggcta tttggttgaa    840

gggattacag agcccaataa aggatttaaa atatattcat taagatttta tttggaaagg    900

tggctggaga gagctgagga tttccaggac tttgtaagtt cttattctgg gagaacataa    960

ggccaataat catgacctct tccaggcatt tttaagacag atgtctattc atgttcttta   1020

gctagagcct gtactttttg ctggcatttg aataacccag tttaaaaaga gtccagttag   1080

ggtggactaa ctttggacac aaattggctt ccatttccta cattttcata ctgctgcctt   1140

cctacagctg ctagaccaag acctgttggt ctgggaagca tttcatggat agggagagct   1200

cctctcggtg aacagtccaa aactaaaata gatgtttata tagaaagccc aagaggagat   1260

ttttgccatg cctgagttct ttcctatccc accctaacac ttaacatatt acttagtctg   1320

ctttgttaaa agcaagtatt acctttaact tgcctcttac tctttgccct ttagctaact   1380

aataaagttt gatataggca ttattatata attctgagtc attcatggta tatctcatgt   1440

ttgatgtatt tttcaaacta agatctatga tagttttttt tccagagttc cattaaatca   1500

tttatttcct ttactttctc acctctgttg aaacatttag aaactggatt tgggaaccca   1560

attttggaaa accagattca tagtcatgaa aatggaaact tccatattct gtttttgaaa   1620

agatgtggcc attattacag taattttatt ataggacttt gcctcgtaca attaatagtg   1680

atattttgga caaggagttc tggtgacaag ctatacctaa ttataagcta taaaacaata   1740

gatatgagtg tttgtacagt ttaactcaat ggagatcaga atattctatg tattgagaaa   1800

atgtttaata tcaatctata aatcttgaat ttctaagagg cttattttgt tcttttggct   1860

gaatgagtat atttgaattg gttgaataat taataattct cattgtaaaa ataattatat   1920

gccaaaaata tatttgatgt taaatcaaat agatgattct gtttacattg ttcatatgaa   1980

taataatctg tgttaatttc attttgataa ttggccttta atatttgtat ctctaatttt   2040

attttctctc tgttactgta aaataatagc tataatgtat aacaattttc ttcagaagaa   2100

ttctatgcta ttattaaaat aaaatattta ctgtgt                             2136


<210>  6813
<211>  136
<212>  PRT
<213>  Homo sapiens

<400>  6813

Met Ile Val Asn Asp Tyr Glu Gly Asn Asp Ser Glu Ala Glu Asp Leu 
1               5                   10                  15


Asn Phe Arg Glu Thr Leu Pro Ser Ser Ser Gln Glu Asn Thr Pro Arg 
            20                  25                  30


Ser Lys Val Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser 
        35                  40                  45


Leu Arg Asn Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro 
    50                  55                  60


Ser Glu Ser Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe 
65                  70                  75                  80


Arg Arg Asp Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser 
                85                  90                  95


Gln Ala Leu Ser Pro Leu Leu Ser Val Gln His His Gly Tyr Ser Gly 
            100                 105                 110


Pro Asn Glu Arg Thr Thr Phe Trp His Gly Ser Asn Glu Gly Ala Val 
        115                 120                 125


Ser Leu Leu Leu Arg Tyr Cys Ala 
    130                 135


<210>  6814
<211>  2504
<212>  DNA
<213>  Homo sapiens

<400>  6814
ccagctgcac tgtgacgcgt gttggggcgc ctatgcgaga cgggaccggg acaggaaccc     60

tgtggctctg tggtagggga atgccaccaa ctccctgagg agcagccgtg tggtatgatt    120

gtaaacgatt atgagggaaa tgactctgaa gcagaagact tgaatttcag ggagactttg    180

ccttcatcaa gtcaggaaaa cacacctaga tcaaaggttt ttgaaaataa agttaattca    240

gagaaggtaa aactttctct tcggaatttc ccacataatg attatgagga tgtttttgaa    300

gagccttcag aaagtggcag tgatcccagc atgtggacag ccagaggccc cttcagaaga    360

gacaggtgga gcagtgagga tgaggaggct gcagggccat cacaggctct ctcccctcta    420

ctttctgata cgcgcaaaat tgtttctgaa ggagaactag atcagttggc tcagattcgg    480

ccattaatat tcaattttca tgagcagaca gccatcaagg attgtttgaa aatccttgag    540

gaaaaaacag cagcgtatga tatcatgcag gaatttatga cgggaactag tcactctgta    600

aaacagttgc agttcaccaa gtggccagac catggcactc ctgcctcagc agatagcttc    660

ataaaatata ttcgttatgc aaggaagagc caccttacag gacccatggt tgttcactgc    720

agtgccggca taggccggac aggggtgttc ctatgtgtgg atgtcgtgtt ctgtgccatc    780

gtaaagaact gttcattcaa catcatggat atagtggccc aaatgagaga acaacgttct    840

ggcatggttc aaacgaagga gcagtatcac ttttgttacg atattgtgct tgaagttctt    900

cggaaacttc tgactttgga ttaagaaaga cttctgttgc ctctcacttg aaattaccaa    960

gtgggtttgc acctcctcat aaagaacatg tttgcactgt gctgaagggc tttgctatgc   1020

atacaatctg ctttcttggt ttatcagttt attttctttc taaaagctcc ctgaagggca   1080

atatcatttg gcttggggtg atcagtgttt acttattgat cttgctagac aatatcaaaa   1140

taacttccca cattttccag tgaaacagat gttacataaa acgattgcag cttggctatt   1200

tggttgaagg gattacagag cccaataaag gatttaaaat atattcatta agattttatt   1260

tggaaaggtg gctggagaga gctgaggatt tccaggactt tgtaagttct tattctggga   1320

gaacataagg ccaataatca tgacctcttc caggcatttt taagacagat gtctattcat   1380

gttctttagc tagagcctgt actttttgct ggcatttgaa taacccagtt taaaaagagt   1440

ccagttaggg tggactaact ttggacacaa attggcttcc atttcctaca ttttcatact   1500

gctgccttcc tacagctgct agaccaagac ctgttggtct gggaagcatt tcatggatag   1560

ggagagctcc tctcggtgaa cagtccaaaa ctaaaataga tgtttatata gaaagcccaa   1620

gaggagattt ttgccatgcc tgagttcttt cctatcccac cctaacactt aacatattac   1680

ttagtctgct ttgttaaaag caagtattac ctttaacttg cctcttactc tttgcccttt   1740

agctaactaa taaagtttga tataggcatt attatataat tctgagtcat tcatggtata   1800

tctcatgttt gatgtatttt tcaaactaag atctatgata gttttttttc cagagttcca   1860

ttaaatcatt tatttccttt actttctcac ctctgttgaa acatttagaa actggatttg   1920

ggaacccaat tttggaaaac cagattcata gtcatgaaaa tggaaacttc catattctgt   1980

ttttgaaaag atgtggccat tattacagta attttattat aggactttgc ctcgtacaat   2040

taatagtgat attttggaca aggagttctg gtgacaagct atacctaatt ataagctata   2100

aaacaataga tatgagtgtt tgtacagttt aactcaatgg agatcagaat attctatgta   2160

ttgagaaaat gtttaatatc aatctataaa tcttgaattt ctaagaggct tattttgttc   2220

ttttggctga atgagtatat ttgaattggt tgaataatta ataattctca ttgtaaaaat   2280

aattatatgc caaaaatata tttgatgtta aatcaaatag atgattctgt ttacattgtt   2340

catatgaata ataatctgtg ttaatttcat tttgataatt ggcctttaat atttgtatct   2400

ctaattttat tttctctctg ttactgtaaa ataatagcta taatgtataa caattttctt   2460

cagaagaatt ctatgctatt attaaaataa aatatttact gtgt                    2504


<210>  6815
<211>  269
<212>  PRT
<213>  Homo sapiens

<400>  6815

Met Ile Val Asn Asp Tyr Glu Gly Asn Asp Ser Glu Ala Glu Asp Leu 
1               5                   10                  15


Asn Phe Arg Glu Thr Leu Pro Ser Ser Ser Gln Glu Asn Thr Pro Arg 
            20                  25                  30


Ser Lys Val Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser 
        35                  40                  45


Leu Arg Asn Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro 
    50                  55                  60


Ser Glu Ser Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe 
65                  70                  75                  80


Arg Arg Asp Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser 
                85                  90                  95


Gln Ala Leu Ser Pro Leu Leu Ser Asp Thr Arg Lys Ile Val Ser Glu 
            100                 105                 110


Gly Glu Leu Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe Asn Phe 
        115                 120                 125


His Glu Gln Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu Glu Glu Lys 
    130                 135                 140


Thr Ala Ala Tyr Asp Ile Met Gln Glu Phe Met Thr Gly Thr Ser His 
145                 150                 155                 160


Ser Val Lys Gln Leu Gln Phe Thr Lys Trp Pro Asp His Gly Thr Pro 
                165                 170                 175


Ala Ser Ala Asp Ser Phe Ile Lys Tyr Ile Arg Tyr Ala Arg Lys Ser 
            180                 185                 190


His Leu Thr Gly Pro Met Val Val His Cys Ser Ala Gly Ile Gly Arg 
        195                 200                 205


Thr Gly Val Phe Leu Cys Val Asp Val Val Phe Cys Ala Ile Val Lys 
    210                 215                 220


Asn Cys Ser Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln 
225                 230                 235                 240


Arg Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp 
                245                 250                 255


Ile Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
            260                 265


<210>  6816
<211>  2930
<212>  DNA
<213>  Homo sapiens

<400>  6816
ccagctgcac tgtgacgcgt gttggggcgc ctatgcgaga cgggaccggg acaggaaccc     60

tgtggctctg tggtagggga atgccaccaa ctccctgagg agcagccgtg tggtatgatt    120

gtaaacgatt atgagggaaa tgactctgaa gcagaagact tgaatttcag ggagactttg    180

ccttcatcaa gtcaggaaaa cacacctaga tcaaaggttt ttgaaaataa agttaattca    240

gagaaggtaa aactttctct tcggaatttc ccacataatg attatgagga tgtttttgaa    300

gagccttcag aaagtggcag tgatcccagc atgtggacag ccagaggccc cttcagaaga    360

gacaggtgga gcagtgagga tgaggaggct gcagggccat cacaggctct ctcccctcta    420

ctttctgata cgcgcaaaat tgtttctgaa ggagaactag atcagttggc tcagattcgg    480

ccattaatat tcaattttca tgagcagaca gccatcaagg attgtttgaa aatccttgag    540

gaaaaaacag cagcgtatga tatcatgcag gaatttatgg ctttagaact taagaatctg    600

cctggtgagt tcaactctgg gaatcaacca agcaacagag aaaaaaacag ataccgagat    660

attcttccat atgattcaac acgcgttcct cttggaaaaa gcaaggacta catcaatgct    720

agttatatta gaatagtcaa ttgtggagaa gagtattttt atatcgctac tcaaggacca    780

ctgctgagca ccatagatga cttttggcaa atggtgttgg aaaataattc aaatgttatt    840

gccatgataa ccagagagat agaaggtgga attatcaaat gctaccatta ctggcccatt    900

tctctgaaga agccattgga attgaaacac ttccgtgtat tcctggagaa ctaccagata    960

cttcaatatt tcatcattcg aatgtttcaa gttgtggaga agtccacggg aactagtcac   1020

tctgtaaaac agttgcagtt caccaagtgg ccagaccatg gcactcctgc ctcagcagat   1080

agcttcataa aatatattcg ttatgcaagg aagagccacc ttacaggacc catggttgtt   1140

cactgcagtg ccggcatagg ccggacaggg gtgttcctat gtgtggatgt cgtgttctgt   1200

gccatcgtaa agaactgttc attcaacatc atggatatag tggcccaaat gagagaacaa   1260

cgttctggca tggttcaaac gaaggagcag tatcactttt gttacgatat tgtgcttgaa   1320

gttcttcgga aacttctgac tttggattaa gaaagacttc tgttgcctct cacttgaaat   1380

taccaagtgg gtttgcacct cctcataaag aacatgtttg cactgtgctg aagggctttg   1440

ctatgcatac aatctgcttt cttggtttat cagtttattt tctttctaaa agctccctga   1500

agggcaatat catttggctt ggggtgatca gtgtttactt attgatcttg ctagacaata   1560

tcaaaataac ttcccacatt ttccagtgaa acagatgtta cataaaacga ttgcagcttg   1620

gctatttggt tgaagggatt acagagccca ataaaggatt taaaatatat tcattaagat   1680

tttatttgga aaggtggctg gagagagctg aggatttcca ggactttgta agttcttatt   1740

ctgggagaac ataaggccaa taatcatgac ctcttccagg catttttaag acagatgtct   1800

attcatgttc tttagctaga gcctgtactt tttgctggca tttgaataac ccagtttaaa   1860

aagagtccag ttagggtgga ctaactttgg acacaaattg gcttccattt cctacatttt   1920

catactgctg ccttcctaca gctgctagac caagacctgt tggtctggga agcatttcat   1980

ggatagggag agctcctctc ggtgaacagt ccaaaactaa aatagatgtt tatatagaaa   2040

gcccaagagg agatttttgc catgcctgag ttctttccta tcccacccta acacttaaca   2100

tattacttag tctgctttgt taaaagcaag tattaccttt aacttgcctc ttactctttg   2160

ccctttagct aactaataaa gtttgatata ggcattatta tataattctg agtcattcat   2220

ggtatatctc atgtttgatg tatttttcaa actaagatct atgatagttt tttttccaga   2280

gttccattaa atcatttatt tcctttactt tctcacctct gttgaaacat ttagaaactg   2340

gatttgggaa cccaattttg gaaaaccaga ttcatagtca tgaaaatgga aacttccata   2400

ttctgttttt gaaaagatgt ggccattatt acagtaattt tattatagga ctttgcctcg   2460

tacaattaat agtgatattt tggacaagga gttctggtga caagctatac ctaattataa   2520

gctataaaac aatagatatg agtgtttgta cagtttaact caatggagat cagaatattc   2580

tatgtattga gaaaatgttt aatatcaatc tataaatctt gaatttctaa gaggcttatt   2640

ttgttctttt ggctgaatga gtatatttga attggttgaa taattaataa ttctcattgt   2700

aaaaataatt atatgccaaa aatatatttg atgttaaatc aaatagatga ttctgtttac   2760

attgttcata tgaataataa tctgtgttaa tttcattttg ataattggcc tttaatattt   2820

gtatctctaa ttttattttc tctctgttac tgtaaaataa tagctataat gtataacaat   2880

tttcttcaga agaattctat gctattatta aaataaaata tttactgtgt              2930


<210>  6817
<211>  411
<212>  PRT
<213>  Homo sapiens

<400>  6817

Met Ile Val Asn Asp Tyr Glu Gly Asn Asp Ser Glu Ala Glu Asp Leu 
1               5                   10                  15


Asn Phe Arg Glu Thr Leu Pro Ser Ser Ser Gln Glu Asn Thr Pro Arg 
            20                  25                  30


Ser Lys Val Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser 
        35                  40                  45


Leu Arg Asn Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro 
    50                  55                  60


Ser Glu Ser Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe 
65                  70                  75                  80


Arg Arg Asp Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser 
                85                  90                  95


Gln Ala Leu Ser Pro Leu Leu Ser Asp Thr Arg Lys Ile Val Ser Glu 
            100                 105                 110


Gly Glu Leu Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe Asn Phe 
        115                 120                 125


His Glu Gln Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu Glu Glu Lys 
    130                 135                 140


Thr Ala Ala Tyr Asp Ile Met Gln Glu Phe Met Ala Leu Glu Leu Lys 
145                 150                 155                 160


Asn Leu Pro Gly Glu Phe Asn Ser Gly Asn Gln Pro Ser Asn Arg Glu 
                165                 170                 175


Lys Asn Arg Tyr Arg Asp Ile Leu Pro Tyr Asp Ser Thr Arg Val Pro 
            180                 185                 190


Leu Gly Lys Ser Lys Asp Tyr Ile Asn Ala Ser Tyr Ile Arg Ile Val 
        195                 200                 205


Asn Cys Gly Glu Glu Tyr Phe Tyr Ile Ala Thr Gln Gly Pro Leu Leu 
    210                 215                 220


Ser Thr Ile Asp Asp Phe Trp Gln Met Val Leu Glu Asn Asn Ser Asn 
225                 230                 235                 240


Val Ile Ala Met Ile Thr Arg Glu Ile Glu Gly Gly Ile Ile Lys Cys 
                245                 250                 255


Tyr His Tyr Trp Pro Ile Ser Leu Lys Lys Pro Leu Glu Leu Lys His 
            260                 265                 270


Phe Arg Val Phe Leu Glu Asn Tyr Gln Ile Leu Gln Tyr Phe Ile Ile 
        275                 280                 285


Arg Met Phe Gln Val Val Glu Lys Ser Thr Gly Thr Ser His Ser Val 
    290                 295                 300


Lys Gln Leu Gln Phe Thr Lys Trp Pro Asp His Gly Thr Pro Ala Ser 
305                 310                 315                 320


Ala Asp Ser Phe Ile Lys Tyr Ile Arg Tyr Ala Arg Lys Ser His Leu 
                325                 330                 335


Thr Gly Pro Met Val Val His Cys Ser Ala Gly Ile Gly Arg Thr Gly 
            340                 345                 350


Val Phe Leu Cys Val Asp Val Val Phe Cys Ala Ile Val Lys Asn Cys 
        355                 360                 365


Ser Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg Ser 
    370                 375                 380


Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile Val 
385                 390                 395                 400


Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
                405                 410


<210>  6818
<211>  2379
<212>  DNA
<213>  Homo sapiens

<400>  6818
ccagctgcac tgtgacgcgt gttggggcgc ctatgcgaga cgggaccggg acaggaaccc     60

tgtggctctg tggtagggga atgccaccaa ctccctgagg agcagccgtg tggtatgatt    120

gtaaacgatt atgagggaaa tgactctgaa gcagaagact tgaatttcag ggagactttg    180

ccttcatcaa gtcaggaaaa cacacctaga tcaaaggttt ttgaaaataa agttaattca    240

gagaaggtaa aactttctct tcggaatttc ccacataatg attatgagga tgtttttgaa    300

gagccttcag aaagtggcag tgatcccagc atgtggacag ccagaggccc cttcagaaga    360

gacaggtgga gcagtgagga tgaggaggct gcagggccat cacaggctct ctcccctcta    420

ctttctgata cgcgcaaaat tgtttctgaa ggagaactag atcagttggc tcagattcgg    480

ccattaatat tcaattttca tgagcagaca gccatcaagg attgtttgaa aatccttgag    540

gaaaaaacag cagcgtatga tatcatgcag gaatttatgg ctttagaact taagaatctg    600

cctggtgagt tcaactctgg gaatcaacca agcaacagag aaaaaaacag ataccgagat    660

attcttccat ttcaacatca tggatatagt ggcccaaatg agagaacaac gttctggcat    720

ggttcaaacg aaggagcagt atcacttttg ttacgatatt gtgcttgaag ttcttcggaa    780

acttctgact ttggattaag aaagacttct gttgcctctc acttgaaatt accaagtggg    840

tttgcacctc ctcataaaga acatgtttgc actgtgctga agggctttgc tatgcataca    900

atctgctttc ttggtttatc agtttatttt ctttctaaaa gctccctgaa gggcaatatc    960

atttggcttg gggtgatcag tgtttactta ttgatcttgc tagacaatat caaaataact   1020

tcccacattt tccagtgaaa cagatgttac ataaaacgat tgcagcttgg ctatttggtt   1080

gaagggatta cagagcccaa taaaggattt aaaatatatt cattaagatt ttatttggaa   1140

aggtggctgg agagagctga ggatttccag gactttgtaa gttcttattc tgggagaaca   1200

taaggccaat aatcatgacc tcttccaggc atttttaaga cagatgtcta ttcatgttct   1260

ttagctagag cctgtacttt ttgctggcat ttgaataacc cagtttaaaa agagtccagt   1320

tagggtggac taactttgga cacaaattgg cttccatttc ctacattttc atactgctgc   1380

cttcctacag ctgctagacc aagacctgtt ggtctgggaa gcatttcatg gatagggaga   1440

gctcctctcg gtgaacagtc caaaactaaa atagatgttt atatagaaag cccaagagga   1500

gatttttgcc atgcctgagt tctttcctat cccaccctaa cacttaacat attacttagt   1560

ctgctttgtt aaaagcaagt attaccttta acttgcctct tactctttgc cctttagcta   1620

actaataaag tttgatatag gcattattat ataattctga gtcattcatg gtatatctca   1680

tgtttgatgt atttttcaaa ctaagatcta tgatagtttt ttttccagag ttccattaaa   1740

tcatttattt cctttacttt ctcacctctg ttgaaacatt tagaaactgg atttgggaac   1800

ccaattttgg aaaaccagat tcatagtcat gaaaatggaa acttccatat tctgtttttg   1860

aaaagatgtg gccattatta cagtaatttt attataggac tttgcctcgt acaattaata   1920

gtgatatttt ggacaaggag ttctggtgac aagctatacc taattataag ctataaaaca   1980

atagatatga gtgtttgtac agtttaactc aatggagatc agaatattct atgtattgag   2040

aaaatgttta atatcaatct ataaatcttg aatttctaag aggcttattt tgttcttttg   2100

gctgaatgag tatatttgaa ttggttgaat aattaataat tctcattgta aaaataatta   2160

tatgccaaaa atatatttga tgttaaatca aatagatgat tctgtttaca ttgttcatat   2220

gaataataat ctgtgttaat ttcattttga taattggcct ttaatatttg tatctctaat   2280

tttattttct ctctgttact gtaaaataat agctataatg tataacaatt ttcttcagaa   2340

gaattctatg ctattattaa aataaaatat ttactgtgt                          2379


<210>  6819
<211>  217
<212>  PRT
<213>  Homo sapiens

<400>  6819

Met Ile Val Asn Asp Tyr Glu Gly Asn Asp Ser Glu Ala Glu Asp Leu 
1               5                   10                  15


Asn Phe Arg Glu Thr Leu Pro Ser Ser Ser Gln Glu Asn Thr Pro Arg 
            20                  25                  30


Ser Lys Val Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser 
        35                  40                  45


Leu Arg Asn Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro 
    50                  55                  60


Ser Glu Ser Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe 
65                  70                  75                  80


Arg Arg Asp Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser 
                85                  90                  95


Gln Ala Leu Ser Pro Leu Leu Ser Asp Thr Arg Lys Ile Val Ser Glu 
            100                 105                 110


Gly Glu Leu Asp Gln Leu Ala Gln Ile Arg Pro Leu Ile Phe Asn Phe 
        115                 120                 125


His Glu Gln Thr Ala Ile Lys Asp Cys Leu Lys Ile Leu Glu Glu Lys 
    130                 135                 140


Thr Ala Ala Tyr Asp Ile Met Gln Glu Phe Met Ala Leu Glu Leu Lys 
145                 150                 155                 160


Asn Leu Pro Gly Glu Phe Asn Ser Gly Asn Gln Pro Ser Asn Arg Glu 
                165                 170                 175


Lys Asn Arg Tyr Arg Asp Ile Leu Pro Phe Gln His His Gly Tyr Ser 
            180                 185                 190


Gly Pro Asn Glu Arg Thr Thr Phe Trp His Gly Ser Asn Glu Gly Ala 
        195                 200                 205


Val Ser Leu Leu Leu Arg Tyr Cys Ala 
    210                 215


<210>  6820
<211>  2477
<212>  DNA
<213>  Homo sapiens

<400>  6820
gacccaactg gcgaggctgc tggggttgca gcgggacagt tggggcggcc ccgcaggccc     60

aggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgt aaacgattat gagggaaatg    240

actctgaagc agaagacttg aatttcaggg agactttgcc ttcatcaagt caggaaaaca    300

cacctagatc aaaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    360

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    420

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    480

aggaggctgc agggccatca caggctctct cccctctact ttctgatacg cgcaaaattg    540

tttctgaagg agaactagat cagttggctc agattcggcc attaatattc aattttcatg    600

agcagacagc catcaaggat tgtttgaaaa tccttgagga aaaaacagca gcgtatgata    660

tcatgcagga atttatggct ttagaactta agaatctgcc tggtgagttc aactctggga    720

atcaaccaag caacagagaa aaaaacagat accgagatat tcttccattt caacatcatg    780

gatatagtgg cccaaatgag agaacaacgt tctggcatgg ttcaaacgaa ggagcagtat    840

cacttttgtt acgatattgt gcttgaagtt cttcggaaac ttctgacttt ggattaagaa    900

agacttctgt tgcctctcac ttgaaattac caagtgggtt tgcacctcct cataaagaac    960

atgtttgcac tgtgctgaag ggctttgcta tgcatacaat ctgctttctt ggtttatcag   1020

tttattttct ttctaaaagc tccctgaagg gcaatatcat ttggcttggg gtgatcagtg   1080

tttacttatt gatcttgcta gacaatatca aaataacttc ccacattttc cagtgaaaca   1140

gatgttacat aaaacgattg cagcttggct atttggttga agggattaca gagcccaata   1200

aaggatttaa aatatattca ttaagatttt atttggaaag gtggctggag agagctgagg   1260

atttccagga ctttgtaagt tcttattctg ggagaacata aggccaataa tcatgacctc   1320

ttccaggcat ttttaagaca gatgtctatt catgttcttt agctagagcc tgtacttttt   1380

gctggcattt gaataaccca gtttaaaaag agtccagtta gggtggacta actttggaca   1440

caaattggct tccatttcct acattttcat actgctgcct tcctacagct gctagaccaa   1500

gacctgttgg tctgggaagc atttcatgga tagggagagc tcctctcggt gaacagtcca   1560

aaactaaaat agatgtttat atagaaagcc caagaggaga tttttgccat gcctgagttc   1620

tttcctatcc caccctaaca cttaacatat tacttagtct gctttgttaa aagcaagtat   1680

tacctttaac ttgcctctta ctctttgccc tttagctaac taataaagtt tgatataggc   1740

attattatat aattctgagt cattcatggt atatctcatg tttgatgtat ttttcaaact   1800

aagatctatg atagtttttt ttccagagtt ccattaaatc atttatttcc tttactttct   1860

cacctctgtt gaaacattta gaaactggat ttgggaaccc aattttggaa aaccagattc   1920

atagtcatga aaatggaaac ttccatattc tgtttttgaa aagatgtggc cattattaca   1980

gtaattttat tataggactt tgcctcgtac aattaatagt gatattttgg acaaggagtt   2040

ctggtgacaa gctataccta attataagct ataaaacaat agatatgagt gtttgtacag   2100

tttaactcaa tggagatcag aatattctat gtattgagaa aatgtttaat atcaatctat   2160

aaatcttgaa tttctaagag gcttattttg ttcttttggc tgaatgagta tatttgaatt   2220

ggttgaataa ttaataattc tcattgtaaa aataattata tgccaaaaat atatttgatg   2280

ttaaatcaaa tagatgattc tgtttacatt gttcatatga ataataatct gtgttaattt   2340

cattttgata attggccttt aatatttgta tctctaattt tattttctct ctgttactgt   2400

aaaataatag ctataatgta taacaatttt cttcagaaga attctatgct attattaaaa   2460

taaaatattt actgtgt                                                  2477


<210>  6821
<211>  226
<212>  PRT
<213>  Homo sapiens

<400>  6821

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
        115                 120                 125


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
    130                 135                 140


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
145                 150                 155                 160


Gln Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro Gly Glu Phe Asn 
                165                 170                 175


Ser Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg Tyr Arg Asp Ile 
            180                 185                 190


Leu Pro Phe Gln His His Gly Tyr Ser Gly Pro Asn Glu Arg Thr Thr 
        195                 200                 205


Phe Trp His Gly Ser Asn Glu Gly Ala Val Ser Leu Leu Leu Arg Tyr 
    210                 215                 220


Cys Ala 
225


<210>  6822
<211>  2386
<212>  DNA
<213>  Homo sapiens

<400>  6822
gacccaactg gcgaggctgc tggggttgca gcgggacagt tggggcggcc ccgcaggccc     60

aggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgt aaacgattat gagggaaatg    240

actctgaagc agaagacttg aatttcaggg agactttgcc ttcatcaagt caggaaaaca    300

cacctagatc aaaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    360

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    420

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    480

aggaggctgc agggccatca caggctctct cccctctact ttctgatacg cgcaaaattg    540

tttctgaagg agaactagat cagttggctc agattcggcc attaatattc aattttcatg    600

agcagacagc catcaaggat tgtttgaaaa tccttgagga aaaaacagca gcgtatgata    660

tcatgcagga atttatgttc aacatcatgg atatagtggc ccaaatgaga gaacaacgtt    720

ctggcatggt tcaaacgaag gagcagtatc acttttgtta cgatattgtg cttgaagttc    780

ttcggaaact tctgactttg gattaagaaa gacttctgtt gcctctcact tgaaattacc    840

aagtgggttt gcacctcctc ataaagaaca tgtttgcact gtgctgaagg gctttgctat    900

gcatacaatc tgctttcttg gtttatcagt ttattttctt tctaaaagct ccctgaaggg    960

caatatcatt tggcttgggg tgatcagtgt ttacttattg atcttgctag acaatatcaa   1020

aataacttcc cacattttcc agtgaaacag atgttacata aaacgattgc agcttggcta   1080

tttggttgaa gggattacag agcccaataa aggatttaaa atatattcat taagatttta   1140

tttggaaagg tggctggaga gagctgagga tttccaggac tttgtaagtt cttattctgg   1200

gagaacataa ggccaataat catgacctct tccaggcatt tttaagacag atgtctattc   1260

atgttcttta gctagagcct gtactttttg ctggcatttg aataacccag tttaaaaaga   1320

gtccagttag ggtggactaa ctttggacac aaattggctt ccatttccta cattttcata   1380

ctgctgcctt cctacagctg ctagaccaag acctgttggt ctgggaagca tttcatggat   1440

agggagagct cctctcggtg aacagtccaa aactaaaata gatgtttata tagaaagccc   1500

aagaggagat ttttgccatg cctgagttct ttcctatccc accctaacac ttaacatatt   1560

acttagtctg ctttgttaaa agcaagtatt acctttaact tgcctcttac tctttgccct   1620

ttagctaact aataaagttt gatataggca ttattatata attctgagtc attcatggta   1680

tatctcatgt ttgatgtatt tttcaaacta agatctatga tagttttttt tccagagttc   1740

cattaaatca tttatttcct ttactttctc acctctgttg aaacatttag aaactggatt   1800

tgggaaccca attttggaaa accagattca tagtcatgaa aatggaaact tccatattct   1860

gtttttgaaa agatgtggcc attattacag taattttatt ataggacttt gcctcgtaca   1920

attaatagtg atattttgga caaggagttc tggtgacaag ctatacctaa ttataagcta   1980

taaaacaata gatatgagtg tttgtacagt ttaactcaat ggagatcaga atattctatg   2040

tattgagaaa atgtttaata tcaatctata aatcttgaat ttctaagagg cttattttgt   2100

tcttttggct gaatgagtat atttgaattg gttgaataat taataattct cattgtaaaa   2160

ataattatat gccaaaaata tatttgatgt taaatcaaat agatgattct gtttacattg   2220

ttcatatgaa taataatctg tgttaatttc attttgataa ttggccttta atatttgtat   2280

ctctaatttt attttctctc tgttactgta aaataatagc tataatgtat aacaattttc   2340

ttcagaagaa ttctatgcta ttattaaaat aaaatattta ctgtgt                  2386


<210>  6823
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  6823

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
        115                 120                 125


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
    130                 135                 140


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
145                 150                 155                 160


Gln Glu Phe Met Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu 
                165                 170                 175


Gln Arg Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr 
            180                 185                 190


Asp Ile Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
        195                 200                 205


<210>  6824
<211>  2602
<212>  DNA
<213>  Homo sapiens

<400>  6824
gacccaactg gcgaggctgc tggggttgca gcgggacagt tggggcggcc ccgcaggccc     60

aggtgaacaa aaattgtttg ctggccccca ggatactaac tagacctttg gcctgactca    120

caggacacta aggctccttt tctgaagaag ccttttacca gtctcattta ggggatggga    180

acaacatgtc ttcacctagg gactttagag cagagcctgt aaacgattat gagggaaatg    240

actctgaagc agaagacttg aatttcaggg agactttgcc ttcatcaagt caggaaaaca    300

cacctagatc aaaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    360

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    420

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    480

aggaggctgc agggccatca caggctctct cccctctact ttctgatacg cgcaaaattg    540

tttctgaagg agaactagat cagttggctc agattcggcc attaatattc aattttcatg    600

agcagacagc catcaaggat tgtttgaaaa tccttgagga aaaaacagca gcgtatgata    660

tcatgcagga atttatgacg ggaactagtc actctgtaaa acagttgcag ttcaccaagt    720

ggccagacca tggcactcct gcctcagcag atagcttcat aaaatatatt cgttatgcaa    780

ggaagagcca ccttacagga cccatggttg ttcactgcag tgccggcata ggccggacag    840

gggtgttcct atgtgtggat gtcgtgttct gtgccatcgt aaagaactgt tcattcaaca    900

tcatggatat agtggcccaa atgagagaac aacgttctgg catggttcaa acgaaggagc    960

agtatcactt ttgttacgat attgtgcttg aagttcttcg gaaacttctg actttggatt   1020

aagaaagact tctgttgcct ctcacttgaa attaccaagt gggtttgcac ctcctcataa   1080

agaacatgtt tgcactgtgc tgaagggctt tgctatgcat acaatctgct ttcttggttt   1140

atcagtttat tttctttcta aaagctccct gaagggcaat atcatttggc ttggggtgat   1200

cagtgtttac ttattgatct tgctagacaa tatcaaaata acttcccaca ttttccagtg   1260

aaacagatgt tacataaaac gattgcagct tggctatttg gttgaaggga ttacagagcc   1320

caataaagga tttaaaatat attcattaag attttatttg gaaaggtggc tggagagagc   1380

tgaggatttc caggactttg taagttctta ttctgggaga acataaggcc aataatcatg   1440

acctcttcca ggcattttta agacagatgt ctattcatgt tctttagcta gagcctgtac   1500

tttttgctgg catttgaata acccagttta aaaagagtcc agttagggtg gactaacttt   1560

ggacacaaat tggcttccat ttcctacatt ttcatactgc tgccttccta cagctgctag   1620

accaagacct gttggtctgg gaagcatttc atggataggg agagctcctc tcggtgaaca   1680

gtccaaaact aaaatagatg tttatataga aagcccaaga ggagattttt gccatgcctg   1740

agttctttcc tatcccaccc taacacttaa catattactt agtctgcttt gttaaaagca   1800

agtattacct ttaacttgcc tcttactctt tgccctttag ctaactaata aagtttgata   1860

taggcattat tatataattc tgagtcattc atggtatatc tcatgtttga tgtatttttc   1920

aaactaagat ctatgatagt tttttttcca gagttccatt aaatcattta tttcctttac   1980

tttctcacct ctgttgaaac atttagaaac tggatttggg aacccaattt tggaaaacca   2040

gattcatagt catgaaaatg gaaacttcca tattctgttt ttgaaaagat gtggccatta   2100

ttacagtaat tttattatag gactttgcct cgtacaatta atagtgatat tttggacaag   2160

gagttctggt gacaagctat acctaattat aagctataaa acaatagata tgagtgtttg   2220

tacagtttaa ctcaatggag atcagaatat tctatgtatt gagaaaatgt ttaatatcaa   2280

tctataaatc ttgaatttct aagaggctta ttttgttctt ttggctgaat gagtatattt   2340

gaattggttg aataattaat aattctcatt gtaaaaataa ttatatgcca aaaatatatt   2400

tgatgttaaa tcaaatagat gattctgttt acattgttca tatgaataat aatctgtgtt   2460

aatttcattt tgataattgg cctttaatat ttgtatctct aattttattt tctctctgtt   2520

actgtaaaat aatagctata atgtataaca attttcttca gaagaattct atgctattat   2580

taaaataaaa tatttactgt gt                                            2602


<210>  6825
<211>  278
<212>  PRT
<213>  Homo sapiens

<400>  6825

Met Ser Ser Pro Arg Asp Phe Arg Ala Glu Pro Val Asn Asp Tyr Glu 
1               5                   10                  15


Gly Asn Asp Ser Glu Ala Glu Asp Leu Asn Phe Arg Glu Thr Leu Pro 
            20                  25                  30


Ser Ser Ser Gln Glu Asn Thr Pro Arg Ser Lys Val Phe Glu Asn Lys 
        35                  40                  45


Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn Phe Pro His Asn 
    50                  55                  60


Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser Gly Ser Asp Pro 
65                  70                  75                  80


Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser 
                85                  90                  95


Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu 
            100                 105                 110


Ser Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
        115                 120                 125


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
    130                 135                 140


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
145                 150                 155                 160


Gln Glu Phe Met Thr Gly Thr Ser His Ser Val Lys Gln Leu Gln Phe 
                165                 170                 175


Thr Lys Trp Pro Asp His Gly Thr Pro Ala Ser Ala Asp Ser Phe Ile 
            180                 185                 190


Lys Tyr Ile Arg Tyr Ala Arg Lys Ser His Leu Thr Gly Pro Met Val 
        195                 200                 205


Val His Cys Ser Ala Gly Ile Gly Arg Thr Gly Val Phe Leu Cys Val 
    210                 215                 220


Asp Val Val Phe Cys Ala Ile Val Lys Asn Cys Ser Phe Asn Ile Met 
225                 230                 235                 240


Asp Ile Val Ala Gln Met Arg Glu Gln Arg Ser Gly Met Val Gln Thr 
                245                 250                 255


Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile Val Leu Glu Val Leu Arg 
            260                 265                 270


Lys Leu Leu Thr Leu Asp 
        275


<210>  6826
<211>  1994
<212>  DNA
<213>  Homo sapiens

<400>  6826
aggctaggcg tggacccaac tggcgaggct gctggggttg cagcgggaca gttggggcgg     60

ccccgcaggc ccaggttttt gaaaataaag ttaattcaga gaaggtaaaa ctttctcttc    120

ggaatttccc acataatgat tatgaggatg tttttgaaga gccttcagaa agtggcagtg    180

atcccagcat gtggacagcc agaggcccct tcagaagaga caggtggagc agtgaggatg    240

aggaggctgc agggccatca caggctctct cccctctact ttctgttcaa catcatggat    300

atagtggccc aaatgagaga acaacgttct ggcatggttc aaacgaagga gcagtatcac    360

ttttgttacg atattgtgct tgaagttctt cggaaacttc tgactttgga ttaagaaaga    420

cttctgttgc ctctcacttg aaattaccaa gtgggtttgc acctcctcat aaagaacatg    480

tttgcactgt gctgaagggc tttgctatgc atacaatctg ctttcttggt ttatcagttt    540

attttctttc taaaagctcc ctgaagggca atatcatttg gcttggggtg atcagtgttt    600

acttattgat cttgctagac aatatcaaaa taacttccca cattttccag tgaaacagat    660

gttacataaa acgattgcag cttggctatt tggttgaagg gattacagag cccaataaag    720

gatttaaaat atattcatta agattttatt tggaaaggtg gctggagaga gctgaggatt    780

tccaggactt tgtaagttct tattctggga gaacataagg ccaataatca tgacctcttc    840

caggcatttt taagacagat gtctattcat gttctttagc tagagcctgt actttttgct    900

ggcatttgaa taacccagtt taaaaagagt ccagttaggg tggactaact ttggacacaa    960

attggcttcc atttcctaca ttttcatact gctgccttcc tacagctgct agaccaagac   1020

ctgttggtct gggaagcatt tcatggatag ggagagctcc tctcggtgaa cagtccaaaa   1080

ctaaaataga tgtttatata gaaagcccaa gaggagattt ttgccatgcc tgagttcttt   1140

cctatcccac cctaacactt aacatattac ttagtctgct ttgttaaaag caagtattac   1200

ctttaacttg cctcttactc tttgcccttt agctaactaa taaagtttga tataggcatt   1260

attatataat tctgagtcat tcatggtata tctcatgttt gatgtatttt tcaaactaag   1320

atctatgata gttttttttc cagagttcca ttaaatcatt tatttccttt actttctcac   1380

ctctgttgaa acatttagaa actggatttg ggaacccaat tttggaaaac cagattcata   1440

gtcatgaaaa tggaaacttc catattctgt ttttgaaaag atgtggccat tattacagta   1500

attttattat aggactttgc ctcgtacaat taatagtgat attttggaca aggagttctg   1560

gtgacaagct atacctaatt ataagctata aaacaataga tatgagtgtt tgtacagttt   1620

aactcaatgg agatcagaat attctatgta ttgagaaaat gtttaatatc aatctataaa   1680

tcttgaattt ctaagaggct tattttgttc ttttggctga atgagtatat ttgaattggt   1740

tgaataatta ataattctca ttgtaaaaat aattatatgc caaaaatata tttgatgtta   1800

aatcaaatag atgattctgt ttacattgtt catatgaata ataatctgtg ttaatttcat   1860

tttgataatt ggcctttaat atttgtatct ctaattttat tttctctctg ttactgtaaa   1920

ataatagcta taatgtataa caattttctt cagaagaatt ctatgctatt attaaaataa   1980

aatatttact gtgt                                                     1994


<210>  6827
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6827

Met Ile Met Arg Met Phe Leu Lys Ser Leu Gln Lys Val Ala Val Ile 
1               5                   10                  15


Pro Ala Cys Gly Gln Pro Glu Ala Pro Ser Glu Glu Thr Gly Gly Ala 
            20                  25                  30


Val Arg Met Arg Arg Leu Gln Gly His His Arg Leu Ser Pro Leu Tyr 
        35                  40                  45


Phe Leu Phe Asn Ile Met Asp Ile Val Ala Gln Met Arg Glu Gln Arg 
    50                  55                  60


Ser Gly Met Val Gln Thr Lys Glu Gln Tyr His Phe Cys Tyr Asp Ile 
65                  70                  75                  80


Val Leu Glu Val Leu Arg Lys Leu Leu Thr Leu Asp 
                85                  90


<210>  6828
<211>  572
<212>  DNA
<213>  Homo sapiens

<400>  6828
gtggacccaa ctggcgaggc tgctggggtt gcagcgggac agttggggcg gccccgcagg     60

cccaggtttt tgaaaataaa gttaattcag agaaggtaaa actttctctt cggaatttcc    120

cacataatga ttatgaggat gtttttgaag agccttcaga aagtggcagt gatcccagca    180

tgtggacagc cagaggcccc ttcagaagag acaggtggag cagtgaggat gaggaggctg    240

cagggccatc acaggctctc tcccctctac tttctgatac gcgcaaaatt gtttctgaag    300

gagaactaga tcagttggct cagattcggc cattaatatt caattttcat gagcagacag    360

ccatcaagga ttgtttgaaa atccttgagg aaaaaacagc agcgtatgat atcatgcagg    420

aatttatggc tttagaactt aagaatctgc ctggtgagtt caactctggg aatcaaccaa    480

gcaacagaga aaaaaacaga taccgagata ttcttccata tgattcaaca cgcgttcctc    540

ttggaaaaag caaggactac atcaatgcta gt                                  572


<210>  6829
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  6829

Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp Arg Trp Ser Ser Glu 
1               5                   10                  15


Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu Ser Pro Leu Leu Ser 
            20                  25                  30


Asp Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala Gln 
        35                  40                  45


Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys Asp 
    50                  55                  60


Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met Gln 
65                  70                  75                  80


Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro Gly Glu Phe Asn Ser 
                85                  90                  95


Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg Tyr Arg Asp Ile Leu 
            100                 105                 110


Pro Tyr Asp Ser Thr Arg Val Pro Leu Gly Lys Ser Lys Asp Tyr Ile 
        115                 120                 125


Asn Ala 
    130


<210>  6830
<211>  507
<212>  DNA
<213>  Homo sapiens

<400>  6830
atggccccaa agagtagtga tgctggcaat ttggatatgc caaagggaag ctatacgcgc     60

aaaattgttt ctgaaggaga actagatcag ttggctcaga ttcggccatt aatattcaat    120

tttcatgagc agacagccat caaggattgt ttgaaaatcc ttgaggaaaa aacagcagcg    180

tatgatatca tgcaggaatt tatggcttta gaacttaaga atctgcctgg tgagttcaac    240

tctgggaatc aaccaagcaa cagagaaaaa aacagatacc gagatattct tccatttata    300

gaagaactag ctgaccaggg acatgctgac actgctactg ctcaaaagac cctagagctg    360

cagcctaagg cacctgtgga aggggaactt accgacatga atgaccaaag tgcttgtgag    420

gaaaaggata aaggcaacct aggggaagca atgatggtag aaaacttgac attaaagaaa    480

ctttggagct atttcacaac aatataa                                        507


<210>  6831
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  6831

Met Ala Pro Lys Ser Ser Asp Ala Gly Asn Leu Asp Met Pro Lys Gly 
1               5                   10                  15


Ser Tyr Thr Arg Lys Ile Val Ser Glu Gly Glu Leu Asp Gln Leu Ala 
            20                  25                  30


Gln Ile Arg Pro Leu Ile Phe Asn Phe His Glu Gln Thr Ala Ile Lys 
        35                  40                  45


Asp Cys Leu Lys Ile Leu Glu Glu Lys Thr Ala Ala Tyr Asp Ile Met 
    50                  55                  60


Gln Glu Phe Met Ala Leu Glu Leu Lys Asn Leu Pro Gly Glu Phe Asn 
65                  70                  75                  80


Ser Gly Asn Gln Pro Ser Asn Arg Glu Lys Asn Arg Tyr Arg Asp Ile 
                85                  90                  95


Leu Pro Phe Ile Glu Glu Leu Ala Asp Gln Gly His Ala Asp Thr Ala 
            100                 105                 110


Thr Ala Gln Lys Thr Leu Glu Leu Gln Pro Lys Ala Pro Val Glu Gly 
        115                 120                 125


Glu Leu Thr Asp Met Asn Asp Gln Ser Ala Cys Glu Glu Lys Asp Lys 
    130                 135                 140


Gly Asn Leu Gly Glu Ala Met Met Val Glu Asn Leu Thr Leu Lys Lys 
145                 150                 155                 160


Leu Trp Ser Tyr Phe Thr Thr Ile 
                165


<210>  6832
<211>  440
<212>  DNA
<213>  Homo sapiens

<400>  6832
cttttaccag tctcatttag gggatgggaa caacatgtct tcacctaggg actttagagc     60

agagcctggt ttttgaaaat aaagttaatt cagagaaggt aaaactttct cttcggaatt    120

tcccacataa tgattatgag gatgtttttg aagagccttc agaaagtggc agtgatccca    180

gcatgtggac agccagaggc cccttcagaa gagacaggtg gagcagtgag gatgaggagg    240

ctgcagggcc atcacaggct ctctcccctc tactttctgg tatgacatca tcctatttgt    300

agtagcaagt tgaggctcta ttttagagat atgcacaaag atatttctaa tacaaatgaa    360

agaaagagct agggaaaact tcaaaaatgg gaaaatatgg ttttctagga ttttctttta    420

aaaataaaaa aatgcaatta                                                440


<210>  6833
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  6833

Met Gly Thr Thr Cys Leu His Leu Gly Thr Leu Glu Gln Ser Leu Val 
1               5                   10                  15


Phe Glu Asn Lys Val Asn Ser Glu Lys Val Lys Leu Ser Leu Arg Asn 
            20                  25                  30


Phe Pro His Asn Asp Tyr Glu Asp Val Phe Glu Glu Pro Ser Glu Ser 
        35                  40                  45


Gly Ser Asp Pro Ser Met Trp Thr Ala Arg Gly Pro Phe Arg Arg Asp 
    50                  55                  60


Arg Trp Ser Ser Glu Asp Glu Glu Ala Ala Gly Pro Ser Gln Ala Leu 
65                  70                  75                  80


Ser Pro Leu Leu Ser Gly Met Thr Ser Ser Tyr Leu 
                85                  90


<210>  6834
<211>  1883
<212>  DNA
<213>  Homo sapiens

<400>  6834
ggagtgagac tgctcagaga ggcaggattc ctgctgactc cagggggaca cctggcacct     60

cagcttcctt tcccacttct ccaggctgca tggaggggtg ccgggcaggg tcctcctgga    120

agggaacctc ctgcagcctc aagcaccagg tcatgacatg acatctatcc ctttcccagg    180

tgaccgactc ctgcaggtgg atggagtgat tctgtgcggc ctcacccaca agcaggctgt    240

gcagtgcctg aagggtcctg ggcaggttgc aagactggtc ttagagagaa gagtccccag    300

gagtacacag cagtgtcctt ctgctaatga cagcatggga gatgaacgca cggctgtttc    360

cttggtaaca gccttgcctg gcaggccttc gagctgtgtc tcggtgacag atggtcctaa    420

gtttgaagtc aaactaaaaa agaatgccaa tggtttggga ttcagtttcg tgcagatgga    480

gaaagagagc tgcagccatc tcaaaagtga tcttgtgagg attaagaggc tctttccggg    540

gcagccagct gaggagaatg gggccattgc agctggtgac attatcctgg ccgtgaatgg    600

aaggtccacg gaaggcctca tcttccagga ggtgctgcat ttactgagag gggccccaca    660

ggaagtcacg ctcctccttt gccgaccccc tccaggtgcg ctgcctgaga tggagcagga    720

atggcagaca cctgaactct cagctgacaa agaattcacc agggcaacat gtactgactc    780

atgtaccagc cccatcctgg atcaagagga cagctggagg gacagtgcct ccccagatgc    840

aggggaaggc ctgggtctca ggccagagtc ttcccaaaag gccatcagag aggcacaatg    900

gggccaaaac agagagagac cttgggccag ttccttgaca cattctcctg agtcccaccc    960

tcatttatgc aaacttcacc aagaaaggga tgaatcaaca ttggcgacct ctttggaaaa   1020

ggatgtgagg caaaactgct attcagtttg tgatatcatg agacttggaa gatattcctt   1080

ctcatctcct ctaaccagac tttcgacaga tattttctga gcaccttctc tgcatgtctg   1140

cagtgctgtg taaaatgccc tacctttgca tggactattc tttctaatca agaggcgtgt   1200

gtggcgaact tggggcagcc cctggaagtc ttgttctttg accattacgt ctgcggctgc   1260

atcaccagat aatgagcttc accacttgtc tgcctcctgt gtccttccgc ggggagtaaa   1320

tgtcacttca gcttgccgca tctctaaata ggcaaatttt cagtgctcag aaaaggacct   1380

gatctttgca caaagtgctt tgatggttgc ctgcttgagt cactcccaat cccttcctga   1440

agccctttct ttataattct tctgttgaaa tagccatcat attcacagta ctaatcacag   1500

catctcacat ttactaaaaa cttaccccat accaggaacc cagagttggg ggggctgtgt   1560

cagaattatg taatttacgt gtcccaataa tcctagatgc ttcttgacca tctagttttg   1620

tcaaatgaga aaactgaggt tccaaagaag tcaataaact tgtccaaagt ctgaccgact   1680

ctgcttgcca tgtgacgagt ctgtcttaga actgggtcat tgccctgctt gcaatgctgt   1740

gccctctggc aagccccccc acccccctgg tctcctgagc tcggtaaggt gctccagctg   1800

cctctaccat agcacttcct acatggactg taacatttct ttactgctcc aacttctcat   1860

taaattgggg gctcctcaaa gcc                                           1883


<210>  6835
<211>  320
<212>  PRT
<213>  Homo sapiens

<400>  6835

Met Thr Ser Ile Pro Phe Pro Gly Asp Arg Leu Leu Gln Val Asp Gly 
1               5                   10                  15


Val Ile Leu Cys Gly Leu Thr His Lys Gln Ala Val Gln Cys Leu Lys 
            20                  25                  30


Gly Pro Gly Gln Val Ala Arg Leu Val Leu Glu Arg Arg Val Pro Arg 
        35                  40                  45


Ser Thr Gln Gln Cys Pro Ser Ala Asn Asp Ser Met Gly Asp Glu Arg 
    50                  55                  60


Thr Ala Val Ser Leu Val Thr Ala Leu Pro Gly Arg Pro Ser Ser Cys 
65                  70                  75                  80


Val Ser Val Thr Asp Gly Pro Lys Phe Glu Val Lys Leu Lys Lys Asn 
                85                  90                  95


Ala Asn Gly Leu Gly Phe Ser Phe Val Gln Met Glu Lys Glu Ser Cys 
            100                 105                 110


Ser His Leu Lys Ser Asp Leu Val Arg Ile Lys Arg Leu Phe Pro Gly 
        115                 120                 125


Gln Pro Ala Glu Glu Asn Gly Ala Ile Ala Ala Gly Asp Ile Ile Leu 
    130                 135                 140


Ala Val Asn Gly Arg Ser Thr Glu Gly Leu Ile Phe Gln Glu Val Leu 
145                 150                 155                 160


His Leu Leu Arg Gly Ala Pro Gln Glu Val Thr Leu Leu Leu Cys Arg 
                165                 170                 175


Pro Pro Pro Gly Ala Leu Pro Glu Met Glu Gln Glu Trp Gln Thr Pro 
            180                 185                 190


Glu Leu Ser Ala Asp Lys Glu Phe Thr Arg Ala Thr Cys Thr Asp Ser 
        195                 200                 205


Cys Thr Ser Pro Ile Leu Asp Gln Glu Asp Ser Trp Arg Asp Ser Ala 
    210                 215                 220


Ser Pro Asp Ala Gly Glu Gly Leu Gly Leu Arg Pro Glu Ser Ser Gln 
225                 230                 235                 240


Lys Ala Ile Arg Glu Ala Gln Trp Gly Gln Asn Arg Glu Arg Pro Trp 
                245                 250                 255


Ala Ser Ser Leu Thr His Ser Pro Glu Ser His Pro His Leu Cys Lys 
            260                 265                 270


Leu His Gln Glu Arg Asp Glu Ser Thr Leu Ala Thr Ser Leu Glu Lys 
        275                 280                 285


Asp Val Arg Gln Asn Cys Tyr Ser Val Cys Asp Ile Met Arg Leu Gly 
    290                 295                 300


Arg Tyr Ser Phe Ser Ser Pro Leu Thr Arg Leu Ser Thr Asp Ile Phe 
305                 310                 315                 320


<210>  6836
<211>  1881
<212>  DNA
<213>  Homo sapiens

<400>  6836
gcttatgaac acctaatctt attgctcagt ggagaataca atctaaacaa acaggtgaat     60

acagaagaca gtgccagtcg gagggtggca ttaacaccag tgtgccatat ggtggtatct    120

atgtgaaatc cattgttcct ggaagaccag ctgccaagga agggcagatc ctacagggtg    180

accgactcct gcaggtggat ggagtgattc tgtgcggcct cacccacaag caggctgtgc    240

agtgcctgaa gggtcctggg caggttgcaa gactggtctt agagagaaga gtccccagga    300

gtacacagca gtgtccttct gctaatgaca gcatgggaga tgaacgcacg gctgtttcct    360

tggtaacagc cttgcctggc aggccttcga gctgtgtctc ggtgacagat ggtcctaagt    420

ttgaagtcaa actaaaaaag aatgccaatg gtttgggatt cagtttcgtg cagatggaga    480

aagagagctg cagccatctc aaaagtgatc ttgtgaggat taagaggctc tttccggggc    540

agccagctga ggagaatggg gccattgcag ctggtgacat tatcctggcc gtgaatggaa    600

ggtccacgga aggcctcatc ttccaggagg tgctgcattt actgagaggg gccccacagg    660

aagtcacgct cctcctttgc cgaccccctc caggtgcgct gcctgagatg gagcaggaat    720

ggcagacacc tgaactctca gctgacaaag aattcaccag ggcaacatgt actgactcat    780

gtaccagccc catcctggat caagaggaca gctggaggga cagtgcctcc ccagatgcag    840

gggaaggcct gggtctcagg ccagagtctt cccaaaaggc catcagagag gcacaatggg    900

gccaaaacag agagagacct tgggccagtt ccttgacaca ttctcctgag tcccaccctc    960

atttatgcaa acttcaccaa gaaagggatg aatcaacatt ggcgacctct ttggaaaagg   1020

atgtgaggca aaactgctat tcagtttgtg atatcatgag acttggaaga tattccttct   1080

catctcctct aaccagactt tcgacagata ttttctgagc accttctctg catgtctgca   1140

gtgctgtgta aaatgcccta cctttgcatg gactattctt tctaatcaag aggcgtgtgt   1200

ggcgaacttg gggcagcccc tggaagtctt gttctttgac cattacgtct gcggctgcat   1260

caccagataa tgagcttcac cacttgtctg cctcctgtgt ccttccgcgg ggagtaaatg   1320

tcacttcagc ttgccgcatc tctaaatagg caaattttca gtgctcagaa aaggacctga   1380

tctttgcaca aagtgctttg atggttgcct gcttgagtca ctcccaatcc cttcctgaag   1440

ccctttcttt ataattcttc tgttgaaata gccatcatat tcacagtact aatcacagca   1500

tctcacattt actaaaaact taccccatac caggaaccca gagttggggg ggctgtgtca   1560

gaattatgta atttacgtgt cccaataatc ctagatgctt cttgaccatc tagttttgtc   1620

aaatgagaaa actgaggttc caaagaagtc aataaacttg tccaaagtct gaccgactct   1680

gcttgccatg tgacgagtct gtcttagaac tgggtcattg ccctgcttgc aatgctgtgc   1740

cctctggcaa gcccccccac ccccctggtc tcctgagctc ggtaaggtgc tccagctgcc   1800

tctaccatag cacttcctac atggactgta acatttcttt actgctccaa cttctcatta   1860

aattgggggc tcctcaaagc c                                             1881


<210>  6837
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  6837

Met Gly Asp Glu Arg Thr Ala Val Ser Leu Val Thr Ala Leu Pro Gly 
1               5                   10                  15


Arg Pro Ser Ser Cys Val Ser Val Thr Asp Gly Pro Lys Phe Glu Val 
            20                  25                  30


Lys Leu Lys Lys Asn Ala Asn Gly Leu Gly Phe Ser Phe Val Gln Met 
        35                  40                  45


Glu Lys Glu Ser Cys Ser His Leu Lys Ser Asp Leu Val Arg Ile Lys 
    50                  55                  60


Arg Leu Phe Pro Gly Gln Pro Ala Glu Glu Asn Gly Ala Ile Ala Ala 
65                  70                  75                  80


Gly Asp Ile Ile Leu Ala Val Asn Gly Arg Ser Thr Glu Gly Leu Ile 
                85                  90                  95


Phe Gln Glu Val Leu His Leu Leu Arg Gly Ala Pro Gln Glu Val Thr 
            100                 105                 110


Leu Leu Leu Cys Arg Pro Pro Pro Gly Ala Leu Pro Glu Met Glu Gln 
        115                 120                 125


Glu Trp Gln Thr Pro Glu Leu Ser Ala Asp Lys Glu Phe Thr Arg Ala 
    130                 135                 140


Thr Cys Thr Asp Ser Cys Thr Ser Pro Ile Leu Asp Gln Glu Asp Ser 
145                 150                 155                 160


Trp Arg Asp Ser Ala Ser Pro Asp Ala Gly Glu Gly Leu Gly Leu Arg 
                165                 170                 175


Pro Glu Ser Ser Gln Lys Ala Ile Arg Glu Ala Gln Trp Gly Gln Asn 
            180                 185                 190


Arg Glu Arg Pro Trp Ala Ser Ser Leu Thr His Ser Pro Glu Ser His 
        195                 200                 205


Pro His Leu Cys Lys Leu His Gln Glu Arg Asp Glu Ser Thr Leu Ala 
    210                 215                 220


Thr Ser Leu Glu Lys Asp Val Arg Gln Asn Cys Tyr Ser Val Cys Asp 
225                 230                 235                 240


Ile Met Arg Leu Gly Arg Tyr Ser Phe Ser Ser Pro Leu Thr Arg Leu 
                245                 250                 255


Ser Thr Asp Ile Phe 
            260


<210>  6838
<211>  1970
<212>  DNA
<213>  Homo sapiens

<400>  6838
gagacaaaca gaggtactgg ggaacctcag gatgagcagg gcatgcacta ggggactcca     60

aactcatgag gaggcagtgt gggcagagtt ggctgatgtg tcctgactct gaggtcaagc    120

tggactgcag agagagagaa gcacattggg gcttcaggga cacaagctaa agggtggcat    180

taacaccagt gtgccatatg gtggtatcta tgtgaaatcc attgttcctg gaagaccagc    240

tgccaaggaa gggcagatcc tacagggtga ccgactcctg caggtggatg gagtgattct    300

gtgcggcctc acccacaagc aggctgtgca gtgcctgaag ggtcctgggc aggttgcaag    360

actggtctta gagagaagag tccccaggag tacacagcag tgtccttctg ctaatgacag    420

catgggagat gaacgcacgg ctgtttcctt ggtaacagcc ttgcctggca ggccttcgag    480

ctgtgtctcg gtgacagatg gtcctaagtt tgaagtcaaa ctaaaaaaga atgccaatgg    540

tttgggattc agtttcgtgc agatggagaa agagagctgc agccatctca aaagtgatct    600

tgtgaggatt aagaggctct ttccggggca gccagctgag gagaatgggg ccattgcagc    660

tggtgacatt atcctggccg tgaatggaag gtccacggaa ggcctcatct tccaggaggt    720

gctgcattta ctgagagggg ccccacagga agtcacgctc ctcctttgcc gaccccctcc    780

aggtgcgctg cctgagatgg agcaggaatg gcagacacct gaactctcag ctgacaaaga    840

attcaccagg gcaacatgta ctgactcatg taccagcccc atcctggatc aagaggacag    900

ctggagggac agtgcctccc cagatgcagg ggaaggcctg ggtctcaggc cagagtcttc    960

ccaaaaggcc atcagagagg cacaatgggg ccaaaacaga gagagacctt gggccagttc   1020

cttgacacat tctcctgagt cccaccctca tttatgcaaa cttcaccaag aaagggatga   1080

atcaacattg gcgacctctt tggaaaagga tgtgaggcaa aactgctatt cagtttgtga   1140

tatcatgaga cttggaagat attccttctc atctcctcta accagacttt cgacagatat   1200

tttctgagca ccttctctgc atgtctgcag tgctgtgtaa aatgccctac ctttgcatgg   1260

actattcttt ctaatcaaga ggcgtgtgtg gcgaacttgg ggcagcccct ggaagtcttg   1320

ttctttgacc attacgtctg cggctgcatc accagataat gagcttcacc acttgtctgc   1380

ctcctgtgtc cttccgcggg gagtaaatgt cacttcagct tgccgcatct ctaaataggc   1440

aaattttcag tgctcagaaa aggacctgat ctttgcacaa agtgctttga tggttgcctg   1500

cttgagtcac tcccaatccc ttcctgaagc cctttcttta taattcttct gttgaaatag   1560

ccatcatatt cacagtacta atcacagcat ctcacattta ctaaaaactt accccatacc   1620

aggaacccag agttgggggg gctgtgtcag aattatgtaa tttacgtgtc ccaataatcc   1680

tagatgcttc ttgaccatct agttttgtca aatgagaaaa ctgaggttcc aaagaagtca   1740

ataaacttgt ccaaagtctg accgactctg cttgccatgt gacgagtctg tcttagaact   1800

gggtcattgc cctgcttgca atgctgtgcc ctctggcaag cccccccacc cccctggtct   1860

cctgagctcg gtaaggtgct ccagctgcct ctaccatagc acttcctaca tggactgtaa   1920

catttcttta ctgctccaac ttctcattaa attgggggct cctcaaagcc              1970


<210>  6839
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  6839

Met Gly Asp Glu Arg Thr Ala Val Ser Leu Val Thr Ala Leu Pro Gly 
1               5                   10                  15


Arg Pro Ser Ser Cys Val Ser Val Thr Asp Gly Pro Lys Phe Glu Val 
            20                  25                  30


Lys Leu Lys Lys Asn Ala Asn Gly Leu Gly Phe Ser Phe Val Gln Met 
        35                  40                  45


Glu Lys Glu Ser Cys Ser His Leu Lys Ser Asp Leu Val Arg Ile Lys 
    50                  55                  60


Arg Leu Phe Pro Gly Gln Pro Ala Glu Glu Asn Gly Ala Ile Ala Ala 
65                  70                  75                  80


Gly Asp Ile Ile Leu Ala Val Asn Gly Arg Ser Thr Glu Gly Leu Ile 
                85                  90                  95


Phe Gln Glu Val Leu His Leu Leu Arg Gly Ala Pro Gln Glu Val Thr 
            100                 105                 110


Leu Leu Leu Cys Arg Pro Pro Pro Gly Ala Leu Pro Glu Met Glu Gln 
        115                 120                 125


Glu Trp Gln Thr Pro Glu Leu Ser Ala Asp Lys Glu Phe Thr Arg Ala 
    130                 135                 140


Thr Cys Thr Asp Ser Cys Thr Ser Pro Ile Leu Asp Gln Glu Asp Ser 
145                 150                 155                 160


Trp Arg Asp Ser Ala Ser Pro Asp Ala Gly Glu Gly Leu Gly Leu Arg 
                165                 170                 175


Pro Glu Ser Ser Gln Lys Ala Ile Arg Glu Ala Gln Trp Gly Gln Asn 
            180                 185                 190


Arg Glu Arg Pro Trp Ala Ser Ser Leu Thr His Ser Pro Glu Ser His 
        195                 200                 205


Pro His Leu Cys Lys Leu His Gln Glu Arg Asp Glu Ser Thr Leu Ala 
    210                 215                 220


Thr Ser Leu Glu Lys Asp Val Arg Gln Asn Cys Tyr Ser Val Cys Asp 
225                 230                 235                 240


Ile Met Arg Leu Gly Arg Tyr Ser Phe Ser Ser Pro Leu Thr Arg Leu 
                245                 250                 255


Ser Thr Asp Ile Phe 
            260


<210>  6840
<211>  1839
<212>  DNA
<213>  Homo sapiens

<400>  6840
gcaggggaca gagctgggat tcagattggc ctccagagca gaaaccttca ccccaggcct     60

tcctctgggt gctggttctt cttgtcctcc atcacctcca gaaatcagtg ctggtgaaat    120

ctactttgtg gaactggtta aagaagatgg gacacttgga ttcagcgtaa ctgtaagagt    180

ttttaggaga gcttgaaaag cagttaacaa gatgtccgtc tagaacctgg tggccattcc    240

acccagatgg caacctctga cagtgtgctt agtttgcaca aatgtaaggg gtaaataaaa    300

aagccaatgg gggcctgcac tgggggatga gttcagagac aaacagaggt actggggaac    360

ctcaggatga gcagggcatg cactagggga ctccaaactc atgaggaggc agtgtgggca    420

gagttggctg atgtgtcctg actctgaggt caagctggac tgcagagaga gagaagcaca    480

ttggggcttc agggacacaa gctaaagggt ggcattaaca ccagtgtgcc atatggtggt    540

atctatgtga aatccattgt tcctggaaga ccagctgcca aggaagggca gatcctacag    600

ggtgaccgac tcctgcaggt ggatggagtg attctgtgcg gcctcaccca caagcaggct    660

gtgcagtgcc tgaagggtcc tgggcaggtt gcaagactgg tcttagagag aagagtcccc    720

aggagtacac agcagtgtcc ttctgctaat gacagcatgg gagatgaacg cacggctgtt    780

tccttggtaa cagccttgcc tggcaggcct tcgagctgtg tctcggtgac agatggtcct    840

aagtttgaag tcaaactaaa aaagaatgcc aatggtttgg gattcagttt cgtgcagatg    900

gagaaagaga gctgcagcca tctcaaaagt gatcttgtga ggattaagag gctctttccg    960

gggcagccag ctgaggagaa tggggccatt gcagctggtg acattatcct ggccgtgaat   1020

ggaaggtcca cggaaggcct catcttccag gaggtgctgc atttactgag aggggcccca   1080

caggaagtca cgctcctcct ttgccgaccc cctccaggtg cgctgcctga gatggagcag   1140

gaatggcaga cacctgaact ctcagctgac aaagaattca ccagggcaac atgtactgac   1200

tcatgtacca gccccatcct ggatcaagag gacagctgga gggacagtgc ctccccagat   1260

gcaggggaag gcctgggtct caggccagag tcttcccaaa aggccatcag agaggcacaa   1320

tggggccaaa acagagagag accttgggcc agttccttga cacattctcc tgagtcccac   1380

cctcatttat gcaaacttca ccaagaaagg gatgaatcaa cattggcgac ctctttggaa   1440

aaggatgtga ggcaaaactg ctattcagtt tgtgatatca tgagacttgg aagagatact   1500

gtaaatccaa cctgccaaaa ctaaatgcag ttgtcaggag cagagacctg gggctcccag   1560

ctgtgtcatc agggctaatg gagacatcag tatggggcct gatgttggag aactggagac   1620

atgaagggac acaaacccca aactttgttg tgagtttaac cgtaagtaaa taggacaatt   1680

ataatacctt catatttcaa gcctgaaatg cccaatctgc ttctatgaat ttcctcctga   1740

aaggcagaga tgaatttggt ggcccaagtc tttaaaggac agctgtccag aaaagttggg   1800

cacagtgtct tttctcagta aacattctgt agcaagcag                          1839


<210>  6841
<211>  255
<212>  PRT
<213>  Homo sapiens

<400>  6841

Met Gly Asp Glu Arg Thr Ala Val Ser Leu Val Thr Ala Leu Pro Gly 
1               5                   10                  15


Arg Pro Ser Ser Cys Val Ser Val Thr Asp Gly Pro Lys Phe Glu Val 
            20                  25                  30


Lys Leu Lys Lys Asn Ala Asn Gly Leu Gly Phe Ser Phe Val Gln Met 
        35                  40                  45


Glu Lys Glu Ser Cys Ser His Leu Lys Ser Asp Leu Val Arg Ile Lys 
    50                  55                  60


Arg Leu Phe Pro Gly Gln Pro Ala Glu Glu Asn Gly Ala Ile Ala Ala 
65                  70                  75                  80


Gly Asp Ile Ile Leu Ala Val Asn Gly Arg Ser Thr Glu Gly Leu Ile 
                85                  90                  95


Phe Gln Glu Val Leu His Leu Leu Arg Gly Ala Pro Gln Glu Val Thr 
            100                 105                 110


Leu Leu Leu Cys Arg Pro Pro Pro Gly Ala Leu Pro Glu Met Glu Gln 
        115                 120                 125


Glu Trp Gln Thr Pro Glu Leu Ser Ala Asp Lys Glu Phe Thr Arg Ala 
    130                 135                 140


Thr Cys Thr Asp Ser Cys Thr Ser Pro Ile Leu Asp Gln Glu Asp Ser 
145                 150                 155                 160


Trp Arg Asp Ser Ala Ser Pro Asp Ala Gly Glu Gly Leu Gly Leu Arg 
                165                 170                 175


Pro Glu Ser Ser Gln Lys Ala Ile Arg Glu Ala Gln Trp Gly Gln Asn 
            180                 185                 190


Arg Glu Arg Pro Trp Ala Ser Ser Leu Thr His Ser Pro Glu Ser His 
        195                 200                 205


Pro His Leu Cys Lys Leu His Gln Glu Arg Asp Glu Ser Thr Leu Ala 
    210                 215                 220


Thr Ser Leu Glu Lys Asp Val Arg Gln Asn Cys Tyr Ser Val Cys Asp 
225                 230                 235                 240


Ile Met Arg Leu Gly Arg Asp Thr Val Asn Pro Thr Cys Gln Asn 
                245                 250                 255


<210>  6842
<211>  596
<212>  DNA
<213>  Homo sapiens

<400>  6842
aactcttaag gatttcacca gacctgttgg ctgctgctgt gatctctgcc caagaggagc     60

ctctgaccaa catccaaagg gcttctggac ccactggact cctctggagc gtcagcctcg    120

agtttgacca gcagcagggg tcggtgtgtc cctctgaatc tgagatctat gaggcaggag    180

ctgaggacag gatggcagga gcgcccatgg ctgctgctgt acagcctgct gaggtgactg    240

ttgaagttgg tgaggacctc cacatgcacc acgttcgtga ccgggagatg cctgaagctt    300

tggagtttaa cctttctgcc aatccagagg caagcacaat attccagagg aactctcaaa    360

cagatgcttt ggagtttaac ccttctgcca atccagaggc aaacacaata ttccagagga    420

actctcaaac agatgttgta gaaataagaa gaagcaactg tacaaaccat gtaagcactg    480

agaagccttt taggaaaatc gggatggatg tgaggcatct ttctgtgaag aaaagcatcc    540

cagaagattc tgattttcac cccaactcaa tcattccaaa ctttgctgct gattga        596


<210>  6843
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  6843

Met Ala Gly Ala Pro Met Ala Ala Ala Val Gln Pro Ala Glu Val Thr 
1               5                   10                  15


Val Glu Val Gly Glu Asp Leu His Met His His Val Arg Asp Arg Glu 
            20                  25                  30


Met Pro Glu Ala Leu Glu Phe Asn Leu Ser Ala Asn Pro Glu Ala Ser 
        35                  40                  45


Thr Ile Phe Gln Arg Asn Ser Gln Thr Asp Ala Leu Glu Phe Asn Pro 
    50                  55                  60


Ser Ala Asn Pro Glu Ala Asn Thr Ile Phe Gln Arg Asn Ser Gln Thr 
65                  70                  75                  80


Asp Val Val Glu Ile Arg Arg Ser Asn Cys Thr Asn His Val Ser Thr 
                85                  90                  95


Glu Lys Pro Phe Arg Lys Ile Gly Met Asp Val Arg His Leu Ser Val 
            100                 105                 110


Lys Lys Ser Ile Pro Glu Asp Ser Asp Phe His Pro Asn Ser Ile Ile 
        115                 120                 125


Pro Asn Phe Ala Ala Asp 
    130


<210>  6844
<211>  445
<212>  DNA
<213>  Homo sapiens

<400>  6844
ggctggtgcc cggggccgcg ctgtgaggtg ggcaggcgag gagcgggaag accatctctg     60

caagtgcagc atagcctcgg cctaggacag cgggagtgcg tggccaaagc tgtgagcaga    120

ggcacaggtg gtggcagaca gtagaggcgc cccatgggga acatactgac ctgtcgtgtg    180

caccctagcg tcagcctcga gtttgaccag cagcaggggt cggtgtgtcc ctctgaatct    240

gagatctatg aggcaggagc tgaggacagg atggcaggag cgcccatggc tgctgctgta    300

cagcctgctg aggtgactgt tgaagttggt gaggacctcc acatgcacca cgttcgtgac    360

cgggagatgc ctgaagcttt ggagtttaac ctttctgcca atccagaggc aagcacaata    420

ttccagagga actctcaaac agatg                                          445


<210>  6845
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  6845

Met Gly Asn Ile Leu Thr Cys Arg Val His Pro Ser Val Ser Leu Glu 
1               5                   10                  15


Phe Asp Gln Gln Gln Gly Ser Val Cys Pro Ser Glu Ser Glu Ile Tyr 
            20                  25                  30


Glu Ala Gly Ala Glu Asp Arg Met Ala Gly Ala Pro Met Ala Ala Ala 
        35                  40                  45


Val Gln Pro Ala Glu Val Thr Val Glu Val Gly Glu Asp Leu His Met 
    50                  55                  60


His His Val Arg Asp Arg Glu Met Pro Glu Ala Leu Glu Phe Asn Leu 
65                  70                  75                  80


Ser Ala Asn Pro Glu Ala Ser Thr Ile Phe Gln Arg Asn Ser Gln Thr 
                85                  90                  95


<210>  6846
<211>  1801
<212>  DNA
<213>  Homo sapiens

<400>  6846
gaatcgggag ggacgcggac ccggtggaac gcactgcgca gacggcgccg gcgccagcac     60

tcggccgttg acgagtcttt cttccagctg tcccctgcaa gtcgtccagg cggcggtccc    120

tttttttctg cctttttgtt tacctccggc gagtcggcgc gagggtgaat ttccgtttcc    180

ggcggtgtcc aagcggacct aaggagtcgc agttgtgaac aggttagagt tacttgttat    240

tggtaaatag ccactatgga gactaaggac cagaagaaac acagaaagaa aaacagtgga    300

cccaaagctg caaagaaaaa gaagtggcat ctgcaggatc tccagctagg agacgaagaa    360

aatgcccaga agagaaatgc caatgctttt gcagttcagt ctgctgtgtg gatgtctcga    420

tcctttcaca ggactctgga tttgaagaca caaaagcatc atattccagt ggttgatgga    480

actccactag agccgccacc aatagcggta gtggtgacgg ggcctccaaa gttggaaaga    540

gcactttgat ataatgcctc attcggaact tcacctggca gaagttcacc gagatcagag    600

gccctgtgac gatcgtgtca ggtaaaaagc gcagactcac cattattgaa tgtgggtgtg    660

acattaacat gatgattgat ctggctaaag tagcagatct ggtactgatg cttatagatg    720

ccagctttgg gtttgaaatg gaaatgtttg agtttctaaa catctgtcaa gcacatggct    780

ttcctaaaat tctgggagtt ctcacccacc tcgactcctt caagcataac aagcaactga    840

agaagacaaa gaagtgatta aaacacaggt tctggacaga agtttaccag gttgccaaac    900

tgttctacct ttctggaatg gtgcatggag aatatcaaaa ccaagaaatc cacaatctgg    960

gccattttat tacagttatg aagtttaggc ctctcatggc aaacttttca cccttatatc   1020

ctggcagaca gttaaaagga tggaagattt gacaaacccg gaggatatcc aaacaaacat   1080

caaatgtgac ctgcaggtgt cactttatgg ttatttaaga ggagcacact tgaaaaataa   1140

aagccaaatt cacatgccag gggtagaaca ttttgccatg agtgacatca gtttcctccc   1200

agacccttgt gttcttcctg aataacaaaa gaagtgctgt ttaaataaga aggagcagct   1260

ggtttatgcg cctgtttctg gagttgaggg tgtgctgtat gacaaagacg ctgtctgtgt   1320

tgaccttggt ggcagccacg gttttcaggc atcagacaag gtggggctca cccatgagct   1380

ggtccagagt ctcatctcca cctactccac cattgatgcc aagatggctt caagtcgagt   1440

gatgctgctt tccaattcca aaccacttgg gtcagaggct atagataatc aaggcaacct   1500

tgcatcccat gggcccttct tctatggcca catgtctctg tggctctttc cttccccctt   1560

ctcttccact gttaaggact catgtgctta cttagtcctg aatggagaca ccgtcatcat   1620

ccacatgagc ccactgtccg aatccgtgag tggtgtcatt gagcaaacac aaagtcgggc   1680

tcatccaagg atgagatttt gccagagaaa ggacgagcag caagtcaggg agcttaaggt   1740

ggtggaaagg aaatccctca cagcaactgg caccataatc aagacaatgt ttgcagaata   1800

a                                                                   1801


<210>  6847
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  6847

Met Ala Ser Ser Arg Val Met Leu Leu Ser Asn Ser Lys Pro Leu Gly 
1               5                   10                  15


Ser Glu Ala Ile Asp Asn Gln Gly Asn Leu Ala Ser His Gly Pro Phe 
            20                  25                  30


Phe Tyr Gly His Met Ser Leu Trp Leu Phe Pro Ser Pro Phe Ser Ser 
        35                  40                  45


Thr Val Lys Asp Ser Cys Ala Tyr Leu Val Leu Asn Gly Asp Thr Val 
    50                  55                  60


Ile Ile His Met Ser Pro Leu Ser Glu Ser Val Ser Gly Val Ile Glu 
65                  70                  75                  80


Gln Thr Gln Ser Arg Ala His Pro Arg Met Arg Phe Cys Gln Arg Lys 
                85                  90                  95


Asp Glu Gln Gln Val Arg Glu Leu Lys Val Val Glu Arg Lys Ser Leu 
            100                 105                 110


Thr Ala Thr Gly Thr Ile Ile Lys Thr Met Phe Ala Glu 
        115                 120                 125


<210>  6848
<211>  962
<212>  DNA
<213>  Homo sapiens

<400>  6848
gaatcgggag ggacgcggac ccggtggaac gcactgcgca gacggcgccg gcgccagcac     60

tcggccgttg acgagtcttt cttccagctg tcccctgcaa gtcgtccagg cggcggtccc    120

tttttttctg cctttttgtt tacctccggc gagtcggcgc gagggtgaat ttccgtttcc    180

ggcggtgtcc aagcggacct aaggagtcgc agttgtgaac aggttagagt tacttgttat    240

tggtaaatag ccactatgga gactaaggac cagaagaaac acagaaagaa aaacagtgga    300

cccaaagctg caaagaaaaa gaagtggcat ctgcaggatc tccagctagg agacgaagaa    360

aatgcccaga agagaaatgc caatgctttt gcagttcagt ctgctgtgtg gatgtctcga    420

tcctttcaca ggactctgga tttgaagaca caaaagcatc atattccagt ggttgatgga    480

actccactag agccgccacc aatagcggta gtggtgacgg ggcctccaaa gttggaaaga    540

gcactttgat ataatgcctc attcggaact tcacctggca gaagttcacc gagatcagag    600

gccctgtgac gatcgtgtca ggtaaaaagc gcagactcac cattattgaa tgtgggtgtg    660

acattaacat gatgattgat ctggctaaag tagcagatct ggtaagtgag caggggcagc    720

ctggggtgct gatggagact tacagcattg tgataggtta tttaccccgt gatgaaggga    780

agagagtttt gtgattatta aaaggatcat ggtcattatc agggatatag tagatgtgat    840

tgaattgatg atgataataa taatagtaat aaatgttgtc atattaataa tacaaatgga    900

atgtgcacaa tgaaatgtgt tccaaaatct aaaagcagat cacaggacgg agaaaacctt    960

ta                                                                   962


<210>  6849
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  6849

Met Glu Thr Lys Asp Gln Lys Lys His Arg Lys Lys Asn Ser Gly Pro 
1               5                   10                  15


Lys Ala Ala Lys Lys Lys Lys Trp His Leu Gln Asp Leu Gln Leu Gly 
            20                  25                  30


Asp Glu Glu Asn Ala Gln Lys Arg Asn Ala Asn Ala Phe Ala Val Gln 
        35                  40                  45


Ser Ala Val Trp Met Ser Arg Ser Phe His Arg Thr Leu Asp Leu Lys 
    50                  55                  60


Thr Gln Lys His His Ile Pro Val Val Asp Gly Thr Pro Leu Glu Pro 
65                  70                  75                  80


Pro Pro Ile Ala Val Val Val Thr Gly Pro Pro Lys Leu Glu Arg Ala 
                85                  90                  95


Leu 



<210>  6850
<211>  2183
<212>  DNA
<213>  Homo sapiens

<400>  6850
ttcatttatt tctttatgaa gacatgatgt atttgttcac tgaacaaggg tagaaactgc     60

ttaaccatcc ccaatttcat ttctctctgt tatgctataa attagatgag ttacctctgc    120

taaggttaca ttctatggtt aagttacttt ttactcgtct caagtgtcaa catcaccagt    180

acctaaccta gacatcgact ggactaacga agtggtttcc taacttaaac taaaacttaa    240

atttcaataa aaaatttaaa acgtttttat gaacttccaa taggatcgca gtattacttt    300

tagtacctgt tgactctaaa acttctaaat tacagctcat ctacatacat ttgaaaaata    360

gcaatatctg tatgtgtgag atatgactgg ttctagatga tgcctggagg ccccatggac    420

ttacagagac ccttccagtg atttctgagg tacctgggaa tctgtggcca ataaattggt    480

agtcactgaa tctgtgagtt tttttggaat atcgggctgc ataaaatctg acagcttgat    540

tgagaaaaag cggggcaggg tgccatttca ttcagttaag gtcctgtgct atggtctgat    600

tgacagagga aatccaaact agtatcttcc gtgccatgca ataagagcta cattgcaagg    660

ctgcagaggg tgctactgga gcacagaagt gagtcaaagg cttcccacag acacacacac    720

gagcggaaac agaaagtctt tatatatcac catatgtcaa gactatattt tactgccgaa    780

cttgtactgt ttctctccct tttcttcttg gtgggaaaag cacaatttgg ggtcaacaga    840

ttcggctcag gtctaagtcg cctgccggga ccacgtcgcc aggaaacgac gtctccccga    900

caccttccct cccagtccgg gctctctgca gggattcatc ccgtcactct cccaacgacc    960

ctcgggcaca cctcaggcag atgcgaaata tgccgctcct ggggagcaaa gatgacccgg   1020

aggaccgggg gagtaccttc ccacgcgcac gactcgcgat cttcccagtg ccccagagcc   1080

acggacccaa ccgccgccta ccccagcccg cggcacctaa cctgttcaca actgcgactc   1140

cttaggtccg cttggacacc gccggaaacg gaaattcacc ctcgcgccga ctcgccggag   1200

gtaaacaaaa aggcagaaaa aaagggaccg ccgcctggac gacttgcagg ggacagctgg   1260

aagaaagact cgtcaacggc cgagtgctgg cgccggcgcc gtctgcgcag tgcgttccac   1320

cgggtccgcg tccctcccga ttcagcccca ccccgccctc ggaatccgct gcctcagctc   1380

ctgctgtggc actccccagc agcttgcacc tcgctcgcgg agtccttgct gaaggccagg   1440

gcagctgtgc ggcctggcgc gggttacttg atgccgtgca aaagccagga gacacatttg   1500

gttctggccg ccccggagtc accgtgcccg gggcgaatgg actatggctg gattgggaga   1560

ccacttcctc ctctgtaaag atgacagacg agggagatct cacgttctgg gggtgcccta   1620

tagccctctt tttaaggccc tctttttccg ggaccaacag actctgaggg cagggacaaa   1680

ctgacccagc ctaaactgcc tcgccttccc tgctcccggg aaaggggttt tccctgaggg   1740

aaggtagcat cttgccattt tcttcctgca cagctttgcc ttcccaggga tccacccatt   1800

gccacctgag gaaatgcctt ggagcccatc taatccccag cccagctact tgggacgcct   1860

acagagacta cattgtcaga ggatgcatct tcctctagtc ttggagggtt tcttttcaat   1920

atgatcccac cggtgcatgc aaggctcaat tctacatcaa aaaactaggc ccactcctgt   1980

cgccgagacc cccaggcttc aggtcctgtc acagtgacct tgttatcacc cccagcagcc   2040

cccagagtcc acagatgtgg ggatctcaag aagcaggcgt tcctggaact gtttcccctt   2100

cctgtgcttc tggtattgaa aaccattcat cacctgcctg aattcttcag tggtcttcaa   2160

agaaaagtaa ataaaatgtt aag                                           2183


<210>  6851
<211>  274
<212>  PRT
<213>  Homo sapiens

<400>  6851

Met Ser Arg Leu Tyr Phe Thr Ala Glu Leu Val Leu Phe Leu Ser Leu 
1               5                   10                  15


Phe Phe Leu Val Gly Lys Ala Gln Phe Gly Val Asn Arg Phe Gly Ser 
            20                  25                  30


Gly Leu Ser Arg Leu Pro Gly Pro Arg Arg Gln Glu Thr Thr Ser Pro 
        35                  40                  45


Arg His Leu Pro Ser Gln Ser Gly Leu Ser Ala Gly Ile His Pro Val 
    50                  55                  60


Thr Leu Pro Thr Thr Leu Gly His Thr Ser Gly Arg Cys Glu Ile Cys 
65                  70                  75                  80


Arg Ser Trp Gly Ala Lys Met Thr Arg Arg Thr Gly Gly Val Pro Ser 
                85                  90                  95


His Ala His Asp Ser Arg Ser Ser Gln Cys Pro Arg Ala Thr Asp Pro 
            100                 105                 110


Thr Ala Ala Tyr Pro Ser Pro Arg His Leu Thr Cys Ser Gln Leu Arg 
        115                 120                 125


Leu Leu Arg Ser Ala Trp Thr Pro Pro Glu Thr Glu Ile His Pro Arg 
    130                 135                 140


Ala Asp Ser Pro Glu Val Asn Lys Lys Ala Glu Lys Lys Gly Pro Pro 
145                 150                 155                 160


Pro Gly Arg Leu Ala Gly Asp Ser Trp Lys Lys Asp Ser Ser Thr Ala 
                165                 170                 175


Glu Cys Trp Arg Arg Arg Arg Leu Arg Ser Ala Phe His Arg Val Arg 
            180                 185                 190


Val Pro Pro Asp Ser Ala Pro Pro Arg Pro Arg Asn Pro Leu Pro Gln 
        195                 200                 205


Leu Leu Leu Trp His Ser Pro Ala Ala Cys Thr Ser Leu Ala Glu Ser 
    210                 215                 220


Leu Leu Lys Ala Arg Ala Ala Val Arg Pro Gly Ala Gly Tyr Leu Met 
225                 230                 235                 240


Pro Cys Lys Ser Gln Glu Thr His Leu Val Leu Ala Ala Pro Glu Ser 
                245                 250                 255


Pro Cys Pro Gly Arg Met Asp Tyr Gly Trp Ile Gly Arg Pro Leu Pro 
            260                 265                 270


Pro Leu 



<210>  6852
<211>  999
<212>  DNA
<213>  Homo sapiens

<400>  6852
atggccatca tcacgggggg cttcgccacc ttctcctcct gcttccccga cctctgcgag     60

ggcgagcctg ctgccctgct acccatgagc ctctcccagt cctgcctgct cgtgcccagc    120

gtgggcctga ccctcatcct gcctcacctc tacctgggct cgcaggaaga cgtcctgaac    180

aaggatctga tgacgcagaa tggaataagc tacgtcctct atgccagcaa ctcctgcccc    240

aagcctgact tcatctacca gagccacttc ttgcaggtcc ccatcaacga caactactgt    300

gaaaagctgc tgccctggct ggacaagtcc atcgagttca tcgataaagc caagctgtcc    360

agctgccaag tcatcgtcca ccatctggcc ggcatctcct gctgtgccac tatcgccatc    420

gcctacatca tgaagaccat gggcatgtcc tccgaagacg cctacaggtt tgtgaaggac    480

cagcgcccgt ccatctcgcc caacttcaac ttcctgggcc agctgctgga gtaccagagc    540

agcccgaagc tgctggccgc cgtgcagggc gacgcgggca ccccctcagg aatgcaggag    600

cctcccccca gccctgcggc cggggcccca ctgccatggc tgccaccacc tacctcagag    660

accgctgcca ccaggagtgc ggctgccagg gagggcggcc cgagcgcggg caggaagccc    720

ccggcgcccc ccacggccac cagcacgctg cagcagggcc tgcgcagcct gcgcctctcc    780

tcggaccacc tgcaggacac cagccgcctc aagccctcct tctctctgga catcaactgg    840

tcagacgagc tggccccgga ttcgcacttc aagtgctgca gctgccagat ggagttcgag    900

gagggcatgg tggaggggcg cgcgcgcagc gaggagctgg ccgccctggg caagcagggg    960

agcttctcgg gcagcgtgga ggtcatcgag atgtcctga                           999


<210>  6853
<211>  332
<212>  PRT
<213>  Homo sapiens

<400>  6853

Met Ala Ile Ile Thr Gly Gly Phe Ala Thr Phe Ser Ser Cys Phe Pro 
1               5                   10                  15


Asp Leu Cys Glu Gly Glu Pro Ala Ala Leu Leu Pro Met Ser Leu Ser 
            20                  25                  30


Gln Ser Cys Leu Leu Val Pro Ser Val Gly Leu Thr Leu Ile Leu Pro 
        35                  40                  45


His Leu Tyr Leu Gly Ser Gln Glu Asp Val Leu Asn Lys Asp Leu Met 
    50                  55                  60


Thr Gln Asn Gly Ile Ser Tyr Val Leu Tyr Ala Ser Asn Ser Cys Pro 
65                  70                  75                  80


Lys Pro Asp Phe Ile Tyr Gln Ser His Phe Leu Gln Val Pro Ile Asn 
                85                  90                  95


Asp Asn Tyr Cys Glu Lys Leu Leu Pro Trp Leu Asp Lys Ser Ile Glu 
            100                 105                 110


Phe Ile Asp Lys Ala Lys Leu Ser Ser Cys Gln Val Ile Val His His 
        115                 120                 125


Leu Ala Gly Ile Ser Cys Cys Ala Thr Ile Ala Ile Ala Tyr Ile Met 
    130                 135                 140


Lys Thr Met Gly Met Ser Ser Glu Asp Ala Tyr Arg Phe Val Lys Asp 
145                 150                 155                 160


Gln Arg Pro Ser Ile Ser Pro Asn Phe Asn Phe Leu Gly Gln Leu Leu 
                165                 170                 175


Glu Tyr Gln Ser Ser Pro Lys Leu Leu Ala Ala Val Gln Gly Asp Ala 
            180                 185                 190


Gly Thr Pro Ser Gly Met Gln Glu Pro Pro Pro Ser Pro Ala Ala Gly 
        195                 200                 205


Ala Pro Leu Pro Trp Leu Pro Pro Pro Thr Ser Glu Thr Ala Ala Thr 
    210                 215                 220


Arg Ser Ala Ala Ala Arg Glu Gly Gly Pro Ser Ala Gly Arg Lys Pro 
225                 230                 235                 240


Pro Ala Pro Pro Thr Ala Thr Ser Thr Leu Gln Gln Gly Leu Arg Ser 
                245                 250                 255


Leu Arg Leu Ser Ser Asp His Leu Gln Asp Thr Ser Arg Leu Lys Pro 
            260                 265                 270


Ser Phe Ser Leu Asp Ile Asn Trp Ser Asp Glu Leu Ala Pro Asp Ser 
        275                 280                 285


His Phe Lys Cys Cys Ser Cys Gln Met Glu Phe Glu Glu Gly Met Val 
    290                 295                 300


Glu Gly Arg Ala Arg Ser Glu Glu Leu Ala Ala Leu Gly Lys Gln Gly 
305                 310                 315                 320


Ser Phe Ser Gly Ser Val Glu Val Ile Glu Met Ser 
                325                 330


<210>  6854
<211>  1446
<212>  DNA
<213>  Homo sapiens

<400>  6854
gggtcatgac gcagcgagtt tcagtcgtga cttttctggg ggcatcgcgg cgtccccttt     60

ttttgccttt aaagtaaaac gtcgccccga cgcacccccc gcgtatttcg gggggcggag    120

gcggcgggcc acggcgcgaa gaggggcggt gctgacgccg gccggtcacg tgggcgtgtt    180

gtggggggga ggggcgccgc cgcgcggtcg gttccgggcg gttgggagcg cacgagctag    240

cgagcgagag gcagccgcgc ccgccgccgc ccctgctctg tatgccgctc tctcccggcg    300

cggccgccgc cgatcacagc agcaggagcc gccgccgccg cggttgatgt ggttgggccg    360

gggctgagga ggccgccaag atgccgcagt caaagtcccg gaagatcgcg atcctgggct    420

accggtctgt ggggaaatcc tcattgacga ttcaatttgt tgaaggccaa tttgtggact    480

cctacgatcc aaccatagaa aacactttta caaagttgat cacagtaaat ggacaagaat    540

atcatcttta acttgtagac acagccgggc aagatgaata ttctatcttt cctcagacat    600

actccataga tattaatggc tatattcttg tgtattctgt tacatcaatc aaaagttttg    660

aagtgattaa agttatccat ggcaaattgt tggatatggt ggggaaagta caaataccta    720

ttatgttggt tggaaataag aaagacctgc atatggaaag ggtgatcagt tatgaagaag    780

ggaaagcttt ggcagaatct tggaatgcag cttttttgga atcttctgct aaagaaaatc    840

agactgctgt tgatgttttt cgaaggatga ttttggaggc agaaaaaatg gacggggcag    900

cttcacaaga ttccagcgta gttagtgacg ttgtacttca agacttactg gcatatgtgt    960

cctcaaaaca ttcctacctc agagatcttc ctccgagaca gcctcagagg gtgaacagta   1020

tagactttgt agaattggag caccttcaac ctgatgtgtt agtccacgca gtactaagag   1080

ttgttgattt cctatactga cagaggcagt atacagttat agaggacaga agcagaaaaa   1140

agttatgtta acagtggaac aggcccaaga tcaacattat gcgcttgtat tatggggtcc   1200

tggagcagcc tggtaccctc aacttcaaag gaaaaaaggt tatatttggg aatttaaata   1260

tctttttgtt cagcgcaatt acacactaga aaacctagaa ttgcatacaa cgccttggtc   1320

atcctgtgag tgcttgtttg atgatgatat aagggcaatt acatttaaag caaaatttca   1380

aaaaagtgca ccctcctttg tgaagatatc agacttagca acccacctag aggataagtg   1440

ttcagg                                                              1446


<210>  6855
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  6855

Met Val Gly Lys Val Gln Ile Pro Ile Met Leu Val Gly Asn Lys Lys 
1               5                   10                  15


Asp Leu His Met Glu Arg Val Ile Ser Tyr Glu Glu Gly Lys Ala Leu 
            20                  25                  30


Ala Glu Ser Trp Asn Ala Ala Phe Leu Glu Ser Ser Ala Lys Glu Asn 
        35                  40                  45


Gln Thr Ala Val Asp Val Phe Arg Arg Met Ile Leu Glu Ala Glu Lys 
    50                  55                  60


Met Asp Gly Ala Ala Ser Gln Asp Ser Ser Val Val Ser Asp Val Val 
65                  70                  75                  80


Leu Gln Asp Leu Leu Ala Tyr Val Ser Ser Lys His Ser Tyr Leu Arg 
                85                  90                  95


Asp Leu Pro Pro Arg Gln Pro Gln Arg Val Asn Ser Ile Asp Phe Val 
            100                 105                 110


Glu Leu Glu His Leu Gln Pro Asp Val Leu Val His Ala Val Leu Arg 
        115                 120                 125


Val Val Asp Phe Leu Tyr 
    130


<210>  6856
<211>  905
<212>  DNA
<213>  Homo sapiens

<400>  6856
gaggtttgca gctattttat ttgcaagtat acatttaaca caatgaaata aacactgata     60

tattgaagcc tagttaatag tagtgtaaca atatgcatca ttttgatgat tacattattt    120

taaacaacaa actacactga aaaattaatg ccaataaaat tcttggtcat aatattaaga    180

aatacaatat ataaattgaa aatatgattg cttaaaattt gaaaatggaa gtgaactcat    240

ttggacagac tcagagttaa cataatctga agggagggga gctctgaccc aaatgatatc    300

tttcaggtta acagaagaaa aaagaagcat agtttatctc caaggagaac gggcagtttg    360

cttcttcagc tagaatatat tcccagtgtc ctcgggcttt gcagcagaat cacatcaccg    420

agcatgaaga cttgccttgt gaagctgccc cgtccatttt ttctgcctcc aaaatcatcc    480

ttcgaaaaac atcaacagca gtctgatttt ctttagcaga agattccaaa aaagctgcat    540

tccaagattc tgccaaagct ttcccttctt cataactgat caccctttcc atatgcaggt    600

ctttcttatt tccaaccaac ataataggta tttgtacttt ccccaccata tccaacaatt    660

tgccatggat aactttaatc acttcaaaac ttttgattga tgtaacagaa tacacaagaa    720

tatagccatt aatatctatg gagtatgtct gaggaaagat agaatattca tcccacagac    780

cggtagccca ggatcgcgat cttccgggac tttgactgcg gcatcttggc ggcctcctca    840

gccccggccc aaccacatca accgcggcgg cggcggctcc tgctgctgtg atcggcggcg    900

gccgc                                                                905


<210>  6857
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  6857

Met Gln Val Phe Leu Ile Ser Asn Gln His Asn Arg Tyr Leu Tyr Phe 
1               5                   10                  15


Pro His His Ile Gln Gln Phe Ala Met Asp Asn Phe Asn His Phe Lys 
            20                  25                  30


Thr Phe Asp 
        35


<210>  6858
<211>  626
<212>  DNA
<213>  Homo sapiens

<400>  6858
agacagtaaa agaaaaggga tgtaacaggt gaaacaagac tgaccatgtt ttaataagct     60

ggctaataga ttcgggtgta catgtgcagg tctgttacct gggaatactg cgtgatactg    120

aactttgggg tacaagtgat cctgtcaccc aggttaacag aagaaaaaag aagcatagtt    180

tatctccaag gagaacgggc agtttgcttc ttcagctaga atatattccc agtgtcctcg    240

ggctttgcag cagaatcaca tcaccgagca tgaagacttg ccttgtgaag ctgccccgtc    300

cattttttct gcctccaaaa tcatccttcg aaaaacatca acagcagtct gattttcttt    360

agcagaagat tccaaaaaag ctgcattcca agattctgcc aaagctttcc cttcttcata    420

actgatcacc ctttccatat gcaggagtcc acaaattggc cttcaacaaa ttgaatcgtc    480

aatgaggatt tccccacaga ccggtagccc aggatcgcga tcttccggga ctttgactgc    540

ggcatcttgg cggcctcctc agccccggcc caaccacatc aaccgcggcg gcggcggctc    600

ctgctgctgt gatcggcggc ggccgc                                         626


<210>  6859
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  6859

Met Cys Arg Ser Val Thr Trp Glu Tyr Cys Val Ile Leu Asn Phe Gly 
1               5                   10                  15


Val Gln Val Ile Leu Ser Pro Arg Leu Thr Glu Glu Lys Arg Ser Ile 
            20                  25                  30


Val Tyr Leu Gln Gly Glu Arg Ala Val Cys Phe Phe Ser 
        35                  40                  45


<210>  6860
<211>  745
<212>  DNA
<213>  Homo sapiens

<400>  6860
ctgtcgctcg ggtccggctg cgggccacag gccgcggatc gcgctctgcc agcgccccac     60

gcccgcaagc gcggcccctc cgccacctcg cggcccggcc tgacctgtta atcacgtccc    120

cacggctctc ctagcgggga caccgccgtc tgcaggctcc gtccccacag tgcccagacc    180

ccgggaagtt tgtcagtcag caccctgatg ccagccgatt ctcaaaaagc caggaggatc    240

caagcagatg atttgccaga cggtactgca gcaatggaga tgaacagata attcacacag    300

aaagaaggac gcaggatgct cgagactctt gcagtaattt gggcaaagat ttccacagtg    360

caaaatagaa aaaacgtaac tggcaaatag ctgtacaaat tacagtccat tttcatcatg    420

gaatgtcagt ttggcaacaa tggcatcgag gcccaaaagc agctctgcag taggggggtt    480

cctccttggt gactggatgg gcacagcgaa gcacaaattc ctgaagatcc cagctccagg    540

aaacatcagc atggttcatt gcgttgtcca cctgaattct tcacccctcc ctgtggctgt    600

gtccattgcc ctgtagtgtt gcagttcccc tcaggaaaaa gatatcattt acttctctga    660

cccttgattt ggagcttggc tatgtgacgt gctttggcca atgggatatt ggatgacata    720

acataaggag agacacagat atgca                                          745


<210>  6861
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  6861

Met Ala Ser Arg Pro Lys Ser Ser Ser Ala Val Gly Gly Phe Leu Leu 
1               5                   10                  15


Gly Asp Trp Met Gly Thr Ala Lys His Lys Phe Leu Lys Ile Pro Ala 
            20                  25                  30


Pro Gly Asn Ile Ser Met Val His Cys Val Val His Leu Asn Ser Ser 
        35                  40                  45


Pro Leu Pro Val Ala Val Ser Ile Ala Leu 
    50                  55


<210>  6862
<211>  1453
<212>  DNA
<213>  Homo sapiens

<400>  6862
actgcgcggc tccccgcgcc gcagctgggc accagcagca ccacggaccg cccctgtgct     60

cgcccgacgg cgccccgcgg cgctttaaga gacggcctgg cagcccagcc ccagccgccc    120

agaccggcga gaccagcctg cgggagcagc cccatggcgg agcagctggc cctggtgatt    180

gggggcacca tcggggggct gctgctgctg ctgttgatcg gggcaagctg ctgtctgtgg    240

agaaggttct gtgccaccct cacctatgag gagctgcctg ggacaccagc catggccacc    300

acagctgcct ccagtgggca gcgggacagg ccctgccagc cgcatgctag gacccaactg    360

agcaggccac cagctgtgcc attcgtggtg cccccaaccc ttcaaggccg agattgggtg    420

cccctgcaca gtggagagtg ggccgatgcc ccatgggacc cctgcccggc atcagagctg    480

ctgcctcaca cctccagcgg cggccttgga gatgcatgta tggtgggggc catcaaccca    540

gagctgtaca agttcccgga ggacaaaagt gagaccgact tccccgacgg ctgcctgggg    600

cggctgtggt tctcggtgga atatgagcag gaggctgagc ggctgctggt gggcttgatc    660

aaggcacagc acctgcaagc cccctcggag acctgcagcc ccctggtgaa gctctacctg    720

ctgcccgatg agcggcgctt cctccaatcc aagaccaaac gcaaaacctc caacccgcag    780

tttgacgagc acttcatctt tcaggtgtcc agcaagacca tcacccagag ggtgctgaag    840

ttctccgtct accacgtgga caggcagagg aagcaccagc tcctgggcca ggtgctcttc    900

cccttgaaga atgagaccct agtgggggac tgccggcgtg tcatctggag agacctggag    960

gccgagagcc tggagccccc ctcggagttt ggcgacctcc agttctgcct cagctacaac   1020

gactacctga gccgcctgac ggtggttgtg ctgcgtgcca agggcctccg gctccaggag   1080

gacagaggca ttgtcagtgt gtttgtcaaa gtgtctctga tgaaccacaa caagtttgtc   1140

aagtgcaaga acctgggcca gacttggggg aggaatcaag aggaagctta aacttaaaat   1200

gaaatcgaaa gtttagactc ctacatggga ttggacattt taaatgctga acagagccta   1260

tttttatagc tagaagttac aggacacatt tttggttaac tgagaatgat ccaaaaatca   1320

tgtgaatttt gtgatccaga aagtcacaga acatgcccta gattttatcc caggggcagg   1380

gaggagtgac ctgcagagta agtttgaatt ggtaaataga aaacaagaat aaaatagttt   1440

gctgtttaca ttc                                                      1453


<210>  6863
<211>  345
<212>  PRT
<213>  Homo sapiens

<400>  6863

Met Ala Glu Gln Leu Ala Leu Val Ile Gly Gly Thr Ile Gly Gly Leu 
1               5                   10                  15


Leu Leu Leu Leu Leu Ile Gly Ala Ser Cys Cys Leu Trp Arg Arg Phe 
            20                  25                  30


Cys Ala Thr Leu Thr Tyr Glu Glu Leu Pro Gly Thr Pro Ala Met Ala 
        35                  40                  45


Thr Thr Ala Ala Ser Ser Gly Gln Arg Asp Arg Pro Cys Gln Pro His 
    50                  55                  60


Ala Arg Thr Gln Leu Ser Arg Pro Pro Ala Val Pro Phe Val Val Pro 
65                  70                  75                  80


Pro Thr Leu Gln Gly Arg Asp Trp Val Pro Leu His Ser Gly Glu Trp 
                85                  90                  95


Ala Asp Ala Pro Trp Asp Pro Cys Pro Ala Ser Glu Leu Leu Pro His 
            100                 105                 110


Thr Ser Ser Gly Gly Leu Gly Asp Ala Cys Met Val Gly Ala Ile Asn 
        115                 120                 125


Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys Ser Glu Thr Asp Phe Pro 
    130                 135                 140


Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser Val Glu Tyr Glu Gln Glu 
145                 150                 155                 160


Ala Glu Arg Leu Leu Val Gly Leu Ile Lys Ala Gln His Leu Gln Ala 
                165                 170                 175


Pro Ser Glu Thr Cys Ser Pro Leu Val Lys Leu Tyr Leu Leu Pro Asp 
            180                 185                 190


Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys Arg Lys Thr Ser Asn Pro 
        195                 200                 205


Gln Phe Asp Glu His Phe Ile Phe Gln Val Ser Ser Lys Thr Ile Thr 
    210                 215                 220


Gln Arg Val Leu Lys Phe Ser Val Tyr His Val Asp Arg Gln Arg Lys 
225                 230                 235                 240


His Gln Leu Leu Gly Gln Val Leu Phe Pro Leu Lys Asn Glu Thr Leu 
                245                 250                 255


Val Gly Asp Cys Arg Arg Val Ile Trp Arg Asp Leu Glu Ala Glu Ser 
            260                 265                 270


Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu Gln Phe Cys Leu Ser Tyr 
        275                 280                 285


Asn Asp Tyr Leu Ser Arg Leu Thr Val Val Val Leu Arg Ala Lys Gly 
    290                 295                 300


Leu Arg Leu Gln Glu Asp Arg Gly Ile Val Ser Val Phe Val Lys Val 
305                 310                 315                 320


Ser Leu Met Asn His Asn Lys Phe Val Lys Cys Lys Asn Leu Gly Gln 
                325                 330                 335


Thr Trp Gly Arg Asn Gln Glu Glu Ala 
            340                 345


<210>  6864
<211>  1886
<212>  DNA
<213>  Homo sapiens

<400>  6864
actgcgcggc tccccgcgcc gcagctgggc accagcagca ccacggaccg cccctgtgct     60

cgcccgacgg cgccccgcgg cgctttaaga gacggcctgg cagcccagcc ccagccgccc    120

agaccggcga gaccagcctg cgggagcagc cccatggcgg agcagctggc cctggtgatt    180

gggggcacca tcggggggct gctgctgctg ctgttgatcg gggcaagctg ctgtctgtgg    240

agaaggttct gtgccaccct cacctatgag gagctgcctg ggacaccagc catggccacc    300

acagctgcct ccagtgggca gcgggacagg ccctgccagc cgcatgctag gacccaactg    360

agcaggccac cagctgtgcc attcgtggtg cccccaaccc ttcaaggccg agattgggtg    420

cccctgcaca gtggagagtg ggccgatgcc ccatgggacc cctgcccggc atcagagctg    480

ctgcctcaca cctccagcgg cggccttgga gatgcatgta tggtgggggc catcaaccca    540

gagctgtaca agttcccgga ggacaaaagt gagaccgact tccccgacgg ctgcctgggg    600

cggctgtggt tctcggtgga atatgagcag gaggctgagc ggctgctggt gggcttgatc    660

aaggcacagc acctgcaagc cccctcggag acctgcagcc ccctggtgaa gctctacctg    720

ctgcccgatg agcggcgctt cctccaatcc aagaccaaac gcaaaacctc caacccgcag    780

tttgacgagc acttcatctt tcaggtgtcc agcaagacca tcacccagag ggtgctgaag    840

ttctccgtct accacgtgga caggcagagg aagcaccagc tcctgggcca ggtgctcttc    900

cccttgaaga atgagaccct agtgggggac tgccggcgtg tcatctggag agacctggag    960

gccgagagcc tggagccccc ctcggagttt ggcgacctcc agttctgcct cagctacaac   1020

gactacctga gccgcctgac ggtggttgtg ctgcgtgcca agggcctccg gctccaggag   1080

gacagaggca ttgtcagtgt gtttgtcaaa gtgtctctga tgaaccacaa caagtttgtc   1140

aagtgcaaga agacttcagc tgtgctgggc tccatcaacc ctgtgtacaa tgagaccttc   1200

agcttcaagg ccgatgccac cgagctggat accgctagcc tcagcctgac tgtggtgcag   1260

aacatggaag gggacaagca ggctactaca gtggaactgt ttctgtttca tctgacatcc   1320

ggatagatgc cagccacccc cacattccaa gattccagtt ctttgatgaa agtctctatt   1380

ccacccatca agtctgtgtc tgataacacc aatatctggg tcattagtgg ctccgttttg   1440

ttgtgtctgt tttcccctcc ttcctgtttt gtggtgtgtt tgatcactta ttgttgaatg   1500

ctaaccatta taataaattt tagtggctcc aggaaacatg atctgaaaac aatgtctgtc   1560

tcaagggagg gtttaccatg tcatctgata gacagagtgg gaagatttta ccttaatcca   1620

atggtaccga actgactaga gtctatgttg cagtttttgg aaggcttcat ctccatctct   1680

ggtttgcccg tctatctaga gtgtggtcct ccaaggattc caactgagtg tctgatgtga   1740

ttattaggct tcttttcctt ggtgggtcct gaactccaac ttttatctca ttaatatgac   1800

actgccaaaa cctgctgctt ttcatagcct ttctgcatag cttaactcag cagatgcctc   1860

aaggggaaag tgttcctttt ctgtgt                                        1886


<210>  6865
<211>  390
<212>  PRT
<213>  Homo sapiens

<400>  6865

Met Ala Glu Gln Leu Ala Leu Val Ile Gly Gly Thr Ile Gly Gly Leu 
1               5                   10                  15


Leu Leu Leu Leu Leu Ile Gly Ala Ser Cys Cys Leu Trp Arg Arg Phe 
            20                  25                  30


Cys Ala Thr Leu Thr Tyr Glu Glu Leu Pro Gly Thr Pro Ala Met Ala 
        35                  40                  45


Thr Thr Ala Ala Ser Ser Gly Gln Arg Asp Arg Pro Cys Gln Pro His 
    50                  55                  60


Ala Arg Thr Gln Leu Ser Arg Pro Pro Ala Val Pro Phe Val Val Pro 
65                  70                  75                  80


Pro Thr Leu Gln Gly Arg Asp Trp Val Pro Leu His Ser Gly Glu Trp 
                85                  90                  95


Ala Asp Ala Pro Trp Asp Pro Cys Pro Ala Ser Glu Leu Leu Pro His 
            100                 105                 110


Thr Ser Ser Gly Gly Leu Gly Asp Ala Cys Met Val Gly Ala Ile Asn 
        115                 120                 125


Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys Ser Glu Thr Asp Phe Pro 
    130                 135                 140


Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser Val Glu Tyr Glu Gln Glu 
145                 150                 155                 160


Ala Glu Arg Leu Leu Val Gly Leu Ile Lys Ala Gln His Leu Gln Ala 
                165                 170                 175


Pro Ser Glu Thr Cys Ser Pro Leu Val Lys Leu Tyr Leu Leu Pro Asp 
            180                 185                 190


Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys Arg Lys Thr Ser Asn Pro 
        195                 200                 205


Gln Phe Asp Glu His Phe Ile Phe Gln Val Ser Ser Lys Thr Ile Thr 
    210                 215                 220


Gln Arg Val Leu Lys Phe Ser Val Tyr His Val Asp Arg Gln Arg Lys 
225                 230                 235                 240


His Gln Leu Leu Gly Gln Val Leu Phe Pro Leu Lys Asn Glu Thr Leu 
                245                 250                 255


Val Gly Asp Cys Arg Arg Val Ile Trp Arg Asp Leu Glu Ala Glu Ser 
            260                 265                 270


Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu Gln Phe Cys Leu Ser Tyr 
        275                 280                 285


Asn Asp Tyr Leu Ser Arg Leu Thr Val Val Val Leu Arg Ala Lys Gly 
    290                 295                 300


Leu Arg Leu Gln Glu Asp Arg Gly Ile Val Ser Val Phe Val Lys Val 
305                 310                 315                 320


Ser Leu Met Asn His Asn Lys Phe Val Lys Cys Lys Lys Thr Ser Ala 
                325                 330                 335


Val Leu Gly Ser Ile Asn Pro Val Tyr Asn Glu Thr Phe Ser Phe Lys 
            340                 345                 350


Ala Asp Ala Thr Glu Leu Asp Thr Ala Ser Leu Ser Leu Thr Val Val 
        355                 360                 365


Gln Asn Met Glu Gly Asp Lys Gln Ala Thr Thr Val Glu Leu Phe Leu 
    370                 375                 380


Phe His Leu Thr Ser Gly 
385                 390


<210>  6866
<211>  3367
<212>  DNA
<213>  Homo sapiens

<400>  6866
agcaagccca aggagctggt gaagcgctgg catgcgctct gccgcaccac ggagccctga     60

cccttcgccc agcaccgcgg ttccgctttg ggagccgacc atcctcgcag ttgcatgtga    120

cagccacagc cacacgcatg gacgtttcat ccaacagctc cccgagctgc cagccagccc    180

gagccaggag gacgtgagtg ctgatatgca ggagagaaga ggggacaaag aagccctggc    240

ccggtcagcg gctctggcca tacagccttc cgacacactc cctcctcctt atctgcgggg    300

ctgcctgggc tcggaatccc ggctcctggt cctcacagcc ctgatttgga ccagaatctc    360

agatgctcag aagaaagatc ctgtttagtg atgacccagc tctacctgct gaatggacct    420

gcagggtaaa cttgggtgcc tccatctggg aaagctgatg atgtgttcat gcagtcgatg    480

accctcactg ctttttcagc cagggtttct ctgccttctg cctggcagag aaaacacact    540

gctatgggga aaatcacagg gagggcgctg tgaccagcgc actcaggcac caagtgtcgg    600

catggctcac tgtgctgggt gaaggcctcc ccgagcatta ggtcctccac ggggctgtgt    660

caaatgccct cccacattgt gtcaagtctg cccatggccc accctcccca cagtccaaaa    720

ccacacagcc ctggttctcc agctgttctg ctgctgtttc tgtgctctcc ctgattaaga    780

gcattcagtt cctgggctct ccctttgagc aggaaatggt gaaagcatgt ggctatggta    840

tagcccacag ggctgagatt gctgtgttgc agtattgatg taaaatttgt taagaaggaa    900

gtacccacag atcactgcca tcaactcccc agaagttgca ctcaagctag tgagcagccc    960

ttgtgcttgt cacagttact gtaacaggta gtgtgtattt gcacctggca tcgtgcagcc   1020

tgcacgtcaa cacgttgttt tgtgtaacta gaacagcaca tggaaccact atctctttct   1080

cttttttcct tctttttctt tttttttttt ttattttaat tttttgagac ggagtttccc   1140

tcttgtcacc caggctggag tgcaatggcg tgatctcggc tcactgcacc ctccacctcc   1200

caggttcaag cgattctcct gcctcagcct cccaaagtgc tgggattaca ggcatgagtc   1260

accgcaccca gcccgaccag tatctttttc ttatgcagtg aaacaacttt agcaaaagag   1320

gcaatgaatg ttatactgag tttctacctc tttaactcca cctccaattt ctgtcaatct   1380

acaaacacaa gtgtcgcctc gcagtgtttc gtatgaacag aatatcttgt gtttgctttt   1440

tgtcacttat ttcacttgca cattttttgt ttgtttgttt gtttgtttgt ttgttttttg   1500

agatggagtc ttgctctgtc gcccaggctg gagtgcggtg gcgcgatcta ggcttactgc   1560

aagctccgcc tcccgggttt acttacacca ctgtcctgcc tcagcctccg gagtagctgg   1620

gactacagac acctgccacc acgccctgct aattttttgt attttcaagt agagacgggg   1680

tttcactgtg ttagccagga tggtctcgat ctcctgacct catgatctac ccgcctcggc   1740

ctcccaaagt gctgggatta caggcgtgag ccaccacgcc cggcccactt gcacattttc   1800

aaagtagtcc gcaaagctgt agtttctaat agcttcatag ctcacatgta ataggggttc   1860

tctgtgtgtt tatagagcag gctactacag tggaactgtt tctgtttcat ctgacatccg   1920

gatagatgcc agccaccccc acattccaag gtgagatttc tgactagcag tgacttttct   1980

agggccgctt ggaaaagttg ataagtatcc ttttctgcag gacagagtag actggtatct   2040

ctgactcatc cctgaaaaat ctaaatggca agagactagc tggctctctg ctctgatggg   2100

gaggaggttg ttgtttgggc tgttctctac agacatagtc agggcaaaaa gcatacgcat   2160

gcttcccatg gaccagagaa acctggcctg ggttgtctca aatcctgtcc acaaggcaac   2220

tccagaagaa agaagccctt tacatttcca taaaacactt tagaatcagc tagtcaattt   2280

ccacaaaata aagtgctaga atttgattgg atttaattga ttatgtagaa caatttgggg   2340

gccatttgac atcattaaaa tattcaatct tcctattcat taacatggta tatctcttca   2400

ctttaagtct tttgtatgtt tctcagaact atttttgtgg ttttcagtaa agtgttcttg   2460

cacatccttc aatagattta ttcttagacg ttttatattt gtttatggct agtatataca   2520

gattctgttg ctacaaaact atgttgacct tgttatccag tgagaggctt tgtgacattc   2580

atttaaattg taataatttg cagattattt ttgtataatc atgtcctctg tgaatgacag   2640

ttttatttct tcctttctta atctttatgc cttatttagc tcttgccaaa ctgcagtggc   2700

tgagcaattg gacaagataa agaaataaaa gtgatccaga tcataaagaa agaagtaaaa   2760

ctatatctgc acatgacata atcttgtcta tggaaaatcc taaggaatcc acacacaaaa   2820

aaactactag agctaataag tttggcaagg ttgcaagata taaaattggt atacaaattg   2880

cagtggctag gacctccagc agaatgctga ctataagtag tgatagtggg tattcttgtc   2940

tcatcctcaa tctcaggggt ggtgggtgtg gcatgtggag agttgtcaat attcaccatg   3000

aagtttgatg gttgttatag gatttttaat gtactcatta acatatattc tcaagctgtt   3060

aaaaagattt ttttaattac aaataaggtt aaatttctct caaatactta ctctgcacct   3120

tttgaaataa ttttattttt ctcctttatt ctttggatgt gatgacttat actaattgac   3180

tgttgaatgt caaaccaaac ttaacattct tgtaatagaa accagcaggg tgtgtacact   3240

tttgtgtgtg tgcgcaggtt tatacacata aacacaacaa tacttggact tatttattta   3300

aaatttagat ttattagagg gagcatggcc ataaaataaa ataaaataaa atttagattt   3360

aagtcga                                                             3367


<210>  6867
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  6867

Met Arg Ser Ala Ala Pro Arg Ser Pro Asp Pro Ser Pro Ser Thr Ala 
1               5                   10                  15


Val Pro Leu Trp Glu Pro Thr Ile Leu Ala Val Ala Cys Asp Ser His 
            20                  25                  30


Ser His Thr His Gly Arg Phe Ile Gln Gln Leu Pro Glu Leu Pro Ala 
        35                  40                  45


Ser Pro Ser Gln Glu Asp Val Ser Ala Asp Met Gln Glu Arg Arg Gly 
    50                  55                  60


Asp Lys Glu Ala Leu Ala Arg Ser Ala Ala Leu Ala Ile Gln Pro Ser 
65                  70                  75                  80


Asp Thr Leu Pro Pro Pro Tyr Leu Arg Gly Cys Leu Gly Ser Glu Ser 
                85                  90                  95


Arg Leu Leu Val Leu Thr Ala Leu Ile Trp Thr Arg Ile Ser Asp Ala 
            100                 105                 110


Gln Lys Lys Asp Pro Val 
        115


<210>  6868
<211>  4862
<212>  DNA
<213>  Homo sapiens

<400>  6868
actgcgcggc tccccgcgcc gcagctgggc accagcagca ccacggaccg cccctgtgct     60

cgcccgacgg cgccccgcgg cgctttaaga gacggcctgg cagcccagcc ccagccgccc    120

agaccggcga gaccagcctg cgggagcagc cccatggcgg agcagctggc cctggtgatt    180

gggggcacca tcggggggct gctgctgctg ctgttgatcg gggcaagctg ctgtctgtgg    240

agaaggttct gtgccaccct cacctatgag gagctgcctg ggacaccagc catggccacc    300

acagctgcct ccagtgggca gcgggacagg ccctgccagc cgcatgctag gacccaactg    360

agcaggccac cagctgtgcc attcgtggtg cccccaaccc ttcaaggccg agattgggtg    420

cccctgcaca gtggagagtg ggccgatgcc ccatgggacc cctgcccggc atcagagctg    480

ctgcctcaca cctccagcgg cggccttgga gatgcatgta tggtgggggc catcaaccca    540

gagctgtaca agttcccgga ggacaaaagt gagaccgact tccccgacgg ctgcctgggg    600

cggctgtggt tctcggtgga atatgagcag gaggctgagc ggctgctggt gggcttgatc    660

aaggcacagc acctgcaagc cccctcggag acctgcagcc ccctggtgaa gctctacctg    720

ctgcccgatg agcggcgctt cctccaatcc aagaccaaac gcaaaacctc caacccgcag    780

tttgacgagc acttcatctt tcaggtgtcc agcaagacca tcacccagag ggtgctgaag    840

ttctccgtct accacgtgga caggcagagg aagcaccagc tcctgggcca ggtgctcttc    900

cccttgaaga atgagaccct agtgggggac tgccggcgtg tcatctggag agacctggag    960

gccgagagcc tggagccccc ctcggagttt ggcgacctcc agttctgcct cagctacaac   1020

gactacctga gccgcctgac ggtggttgtg ctgcgtgcca agggcctccg gctccaggag   1080

gacagaggca ttgtcagtgt gtttgtcaaa gtgtctctga tgaaccacaa caagtttgtc   1140

aagtgcaaga agacttcagc tgtgctgggc tccatcaacc ctgtgtacaa tgagaccttc   1200

agcttcaagg ccgatgccac cgagctggat accgctagcc tcagcctgac tgtggtgcag   1260

aacatggaag gggacaagag ccagcagctg ggccgagtgg tggtgggccc ctacatgtac   1320

acccgcggca gagagctgga gcactgggac gagatgctca gcaagcccaa ggagctggtg   1380

aagcgctggc atgcgctctg ccgcaccacg gagccctgac ccttcgccca gcaccgcggt   1440

tccgctttgg gagccgacca tcctcgcagt tgcatgtgac agccacagcc acacgcatgg   1500

acgtttcatc caacagctcc ccgagctgcc agccagcccg agccaggagg acgtgagtgc   1560

tgatatgcag gagagaagag gggacaaaga agccctggcc cggtcagcgg ctctggccat   1620

acagccttcc gacacactcc ctcctcctta tctgcggggc tgcctgggct cggaatcccg   1680

gctcctggtc ctcacagccc tgatttggac cagaatctca gatgctcaga agaaagatcc   1740

tgtttagtga tgacccagct ctacctgctg aatggacctg cagggtaaac ttgggtgcct   1800

ccatctggga aagctgatga tgtgttcatg cagtcgatga ccctcactgc tttttcagcc   1860

agggtttctc tgccttctgc ctggcagaga aaacacactg ctatggggaa aatcacaggg   1920

agggcgctgt gaccagcgca ctcaggcacc aagtgtcggc atggctcact gtgctgggtg   1980

aaggcctccc cgagcattag gtcctccacg gggctgtgtc aaatgccctc ccacattgtg   2040

tcaagtctgc ccatggccca ccctccccac agtccaaaac cacacagccc tggttctcca   2100

gctgttctgc tgctgtttct gtgctctccc tgattaagag cattcagttc ctgggctctc   2160

cctttgagca ggaaatggtg aaagcatgtg gctatggtat agcccacagg gctgagattg   2220

ctgtgttgca gtattgatgt aaaatttgtt aagaaggaag tacccacaga tcactgccat   2280

caactcccca gaagttgcac tcaagctagt gagcagccct tgtgcttgtc acagttactg   2340

taacaggtag tgtgtatttg cacctggcat cgtgcagcct gcacgtcaac acgttgtttt   2400

gtgtaactag aacagcacat ggaaccacta tctctttctc ttttttcctt ctttttcttt   2460

tttttttttt tattttaatt ttttgagacg gagtttccct cttgtcaccc aggctggagt   2520

gcaatggcgt gatctcggct cactgcaccc tccacctccc aggttcaagc gattctcctg   2580

cctcagcctc ccaagtagct gggattactg gcgcccgcca ccatgcctgg ctaatttttt   2640

ttatttttag tagagacgga attttaccat gttggctagg ctggtctcaa attcctggcc   2700

tcaggtgatc cacctgcctc agcctcccaa agtgctggga ttacaggcat gagtcaccgc   2760

acccagcccg accagtatct ttttcttatg cagtgaaaca actttagcaa aagaggcaat   2820

gaatgttata ctgagtttct acctctttaa ctccacctcc aatttctgtc aatctacaaa   2880

cacaagtgtc gcctcgcagt gtttcgtatg aacagaatat cttgtgtttg ctttttgtca   2940

cttatttcac ttgcacattt tttgtttgtt tgtttgtttg tttgtttgtt ttttgagatg   3000

gagtcttgct ctgtcgccca ggctggagtg cggtggcgcg atctaggctt actgcaagct   3060

ccgcctcccg ggtttactta caccactgtc ctgcctcagc ctccggagta gctgggacta   3120

cagacacctg ccaccacgcc ctgctaattt tttgtatttt caagtagaga cggggtttca   3180

ctgtgttagc caggatggtc tcgatctcct gacctcatga tctacccgcc tcggcctccc   3240

aaagtgctgg gattacaggc gtgagccacc acgcccggcc cacttgcaca ttttcaaagt   3300

agtccgcaaa gctgtagttt ctaatagctt catagctcac atgtaatagg ggttctctgt   3360

gtgtttatag agcaggctac tacagtggaa ctgtttctgt ttcatctgac atccggatag   3420

atgccagcca cccccacatt ccaaggtgag atttctgact agcagtgact tttctagggc   3480

cgcttggaaa agttgataag tatccttttc tgcaggacag agtagactgg tatctctgac   3540

tcatccctga aaaatctaaa tggcaagaga ctagctggct ctctgctctg atggggagga   3600

ggttgttgtt tgggctgttc tctacagaca tagtcagggc aaaaagcata cgcatgcttc   3660

ccatggacca gagaaacctg gcctgggttg tctcaaatcc tgtccacaag gcaactccag   3720

aagaaagaag ccctttacat ttccataaaa cactttagaa tcagctagtc aatttccaca   3780

aaataaagtg ctagaatttg attggattta attgattatg tagaacaatt tgggggccat   3840

ttgacatcat taaaatattc aatcttccta ttcattaaca tggtatatct cttcacttta   3900

agtcttttgt atgtttctca gaactatttt tgtggttttc agtaaagtgt tcttgcacat   3960

ccttcaatag atttattctt agacgtttta tatttgttta tggctagtat atacagattc   4020

tgttgctaca aaactatgtt gaccttgtta tccagtgaga ggctttgtga cattcattta   4080

aattgtaata atttgcagat tatttttgta taatcatgtc ctctgtgaat gacagtttta   4140

tttcttcctt tcttaatctt tatgccttat ttagctcttg ccaaactgca gtggctgagc   4200

aattggacaa gataaagaaa taaaagtgat ccagatcata aagaaagaag taaaactata   4260

tctgcacatg acataatctt gtctatggaa aatcctaagg aatccacaca caaaaaaact   4320

actagagcta ataagtttgg caaggttgca agatataaaa ttggtataca aattgcagtg   4380

gctaggacct ccagcagaat gctgactata agtagtgata gtgggtattc ttgtctcatc   4440

ctcaatctca ggggtggtgg gtgtggcatg tggagagttg tcaatattca ccatgaagtt   4500

tgatggttgt tataggattt ttaatgtact cattaacata tattctcaag ctgttaaaaa   4560

gattttttta attacaaata aggttaaatt tctctcaaat acttactctg caccttttga   4620

aataatttta tttttctcct ttattctttg gatgtgatga cttatactaa ttgactgttg   4680

aatgtcaaac caaacttaac attcttgtaa tagaaaccag cagggtgtgt acacttttgt   4740

gtgtgtgcgc aggtttatac acataaacac aacaatactt ggacttattt atttaaaatt   4800

tagatttatt agagggagca tggccataaa ataaaataaa ataaaattta gatttaagtc   4860

ga                                                                  4862


<210>  6869
<211>  421
<212>  PRT
<213>  Homo sapiens

<400>  6869

Met Ala Glu Gln Leu Ala Leu Val Ile Gly Gly Thr Ile Gly Gly Leu 
1               5                   10                  15


Leu Leu Leu Leu Leu Ile Gly Ala Ser Cys Cys Leu Trp Arg Arg Phe 
            20                  25                  30


Cys Ala Thr Leu Thr Tyr Glu Glu Leu Pro Gly Thr Pro Ala Met Ala 
        35                  40                  45


Thr Thr Ala Ala Ser Ser Gly Gln Arg Asp Arg Pro Cys Gln Pro His 
    50                  55                  60


Ala Arg Thr Gln Leu Ser Arg Pro Pro Ala Val Pro Phe Val Val Pro 
65                  70                  75                  80


Pro Thr Leu Gln Gly Arg Asp Trp Val Pro Leu His Ser Gly Glu Trp 
                85                  90                  95


Ala Asp Ala Pro Trp Asp Pro Cys Pro Ala Ser Glu Leu Leu Pro His 
            100                 105                 110


Thr Ser Ser Gly Gly Leu Gly Asp Ala Cys Met Val Gly Ala Ile Asn 
        115                 120                 125


Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys Ser Glu Thr Asp Phe Pro 
    130                 135                 140


Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser Val Glu Tyr Glu Gln Glu 
145                 150                 155                 160


Ala Glu Arg Leu Leu Val Gly Leu Ile Lys Ala Gln His Leu Gln Ala 
                165                 170                 175


Pro Ser Glu Thr Cys Ser Pro Leu Val Lys Leu Tyr Leu Leu Pro Asp 
            180                 185                 190


Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys Arg Lys Thr Ser Asn Pro 
        195                 200                 205


Gln Phe Asp Glu His Phe Ile Phe Gln Val Ser Ser Lys Thr Ile Thr 
    210                 215                 220


Gln Arg Val Leu Lys Phe Ser Val Tyr His Val Asp Arg Gln Arg Lys 
225                 230                 235                 240


His Gln Leu Leu Gly Gln Val Leu Phe Pro Leu Lys Asn Glu Thr Leu 
                245                 250                 255


Val Gly Asp Cys Arg Arg Val Ile Trp Arg Asp Leu Glu Ala Glu Ser 
            260                 265                 270


Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu Gln Phe Cys Leu Ser Tyr 
        275                 280                 285


Asn Asp Tyr Leu Ser Arg Leu Thr Val Val Val Leu Arg Ala Lys Gly 
    290                 295                 300


Leu Arg Leu Gln Glu Asp Arg Gly Ile Val Ser Val Phe Val Lys Val 
305                 310                 315                 320


Ser Leu Met Asn His Asn Lys Phe Val Lys Cys Lys Lys Thr Ser Ala 
                325                 330                 335


Val Leu Gly Ser Ile Asn Pro Val Tyr Asn Glu Thr Phe Ser Phe Lys 
            340                 345                 350


Ala Asp Ala Thr Glu Leu Asp Thr Ala Ser Leu Ser Leu Thr Val Val 
        355                 360                 365


Gln Asn Met Glu Gly Asp Lys Ser Gln Gln Leu Gly Arg Val Val Val 
    370                 375                 380


Gly Pro Tyr Met Tyr Thr Arg Gly Arg Glu Leu Glu His Trp Asp Glu 
385                 390                 395                 400


Met Leu Ser Lys Pro Lys Glu Leu Val Lys Arg Trp His Ala Leu Cys 
                405                 410                 415


Arg Thr Thr Glu Pro 
            420


<210>  6870
<211>  3537
<212>  DNA
<213>  Homo sapiens

<400>  6870
gttctaataa tcaccataat aataggcgct gggtgtacag aggggaccca ggcgacgctg     60

gcctccatcc gataaccacc gtaacagggg ctgggccgcg ccgctcctcc gctctaagtg    120

ctctttacat gcttcttaag ttaccggcag gccagccgcc cttacgagag cccctcacgg    180

acattaaccc aattgagaag actgaaccca gcttacgaac gttaagttgt cccaaatcgc    240

agggctggcg agtgaggagc ctgaattgga acccaggagc ttctggaacc cgctccagaa    300

ttgcgctctc gaccggtttg tccgctgaga gcgaacgggt gcgcgagcgc cgcatccctg    360

cccaaggcca tcaggcaggc agcgctgggg ccggggaccc gcgcggagac tccaccccgg    420

gatccgggaa ggctcccccg agccggggtc ggagctgcgg ctggaggggc ctcggcttga    480

ggaggatctg ggagggcggg ggctcagtcc tggccaccag gtgtgagggg tcgggtgcgg    540

agccctgtgt cagacgcggc ggtgaaggct gtagccctgc tctccgggat gggggtggta    600

ctctcacccc accctgcccc aagccgcagg gagcccctgg cgcccctggc gcccgggacc    660

cgccctggct ggagccctgc ggtttccggg agctcacggt cggctctgcg cccctccacc    720

gccgggcctg ggcctgggcc agggacgggc tggggcggga ctgcggcctc ggggcgctgg    780

gtccctgccc ctgccgtgca ctgcgcggct ccccgcgccg cagctgggca ccagcagcac    840

cacggaccgc ccctgtgctc gcccgacggc gccccgcggc gctttaagag acggcctggc    900

agcccagccc cagccgccca gaccggcgag accagcctgc gggagcagcc ccatggcggg    960

ccaccagctg tgccattcgt ggtgccccca acccttcaag gccgagattg ggtgcccctg   1020

cacagtggag agtgggccga tgccccatgg gacccctgcc cggcatcaga gctgctgcct   1080

cacacctcca gcggcggcct tggagatgca tgtatggtgg gggccatcaa cccagagctg   1140

tacaagttcc cggaggacaa aagtgagacc gacttccccg acggctgcct ggggcggctg   1200

tggttctcgg tggaatatga gcaggaggct gagcggctgc tggtgggctt gatcaaggca   1260

cagcacctgc aagccccctc ggagacctgc agccccctgg tgaagctcta cctgctgccc   1320

gatgagcggc gcttcctcca atccaagacc aaacgcaaaa cctccaaccc gcagtttgac   1380

gagcacttca tctttcaggt gtccagcaag accatcaccc agagggtgct gaagttctcc   1440

gtctaccacg tggacaggca gaggaagcac cagctcctgg gccaggtgct cttccccttg   1500

aagaatgaga ccctagtggg ggactgccgg cgtgtcatct ggagagacct ggaggccgag   1560

agcctggagc ccccctcgga gtttggcgac ctccagttct gcctcagcta caacgactac   1620

ctgagccgcc tgacggtggt tgtgctgcgt gccaagggcc tccggctcca ggaggacaga   1680

ggcattgtca gtgtgtttgt caaagtgtct ctgatgaacc acaacaagtt tgtcaagtgc   1740

aagaagactt cagctgtgct gggctccatc aaccctgtgt acaatgagac cttcagcttc   1800

aaggccgatg ccaccgagct ggataccgct agcctcagcc tgactgtggt gcagaacatg   1860

gaaggggaca agagccagca gctgggccga gtggtggtgg gcccctacat gtacacccgc   1920

ggcagagagc tggagcactg ggacgagatg ctcagcaagc ccaaggagct ggtgaagcgc   1980

tggcatgcgc tctgccgcac cacggagccc tgacccttcg cccagcaccg cggttccgct   2040

ttgggagccg accatcctcg cagttgcatg tgacagccac agccacacgc atggacgttt   2100

catccaacag ctccccgagc tgccagccag cccgagccag gaggacgtga gtgctgatat   2160

gcaggagaga agaggggaca aagaagccct ggcccggtca gcggctctgg ccatacagcc   2220

ttccgacaca ctccctcctc cttatctgcg gggctgcctg ggctcggaat cccggctcct   2280

ggtcctcaca gccctgattt ggaccagaat ctcagatgct cagaagaaag atcctgttta   2340

gtgatgaccc agctctacct gctgaatgga cctgcagggt aaacttgggt gcctccatct   2400

gggaaagctg atgatgtgtt catgcagtcg atgaccctca ctgctttttc agccagggtt   2460

tctctgcctt ctgcctggca gagaaaacac actgctatgg ggaaaatcac agggagggcg   2520

ctgtgaccag cgcactcagg caccaagtgt cggcatggct cactgtgctg ggtgaaggcc   2580

tccccgagca ttaggtcctc cacggggctg tgtcaaatgc cctcccacat tgtgtcaagt   2640

ctgcccatgg cccaccctcc ccacagtcca aaaccacaca gccctggttc tccagctgtt   2700

ctgctgctgt ttctgtgctc tccctgatta agagcattca gttcctgggc tctccctttg   2760

agcaggaaat ggtgaaagca tgtggctatg gtatagccca cagggctgag attgctgtgt   2820

tgcagtattg atgtaaaatt tgttaagaag gaagtaccca cagatcactg ccatcaactc   2880

cccagaagtt gcactcaagc tagtgagcag cccttgtgct tgtcacagtt actgtaacag   2940

gtagtgtgta tttgcacctg gcatcgtgca gcctgcacgt caacacgttg ttttgtgtaa   3000

ctagaacagc acatggaacc actatctctt tctctttttt ccttcttttt cttttttttt   3060

tttttatttt aattttttga gacggagttt ccctcttgtc acccaggctg gagtgcaatg   3120

gcgtgatctc ggctcactgc accctccacc tcccaggttc aagcgattct cctgcctcag   3180

cctcccaagt agctgggatt actggcgccc gccaccatgc ctggctaatt ttttttattt   3240

ttagtagaga cggaatttta ccatgttggc taggctggtc tcaaattcct ggcctcaggt   3300

gatccacctg cctcagcctc ccaaagtgct gggattacag gcatgagtca ccgcacccag   3360

cccgaccagt atctttttct tatgcagtga aacaacttta gcaaaagagg caatgaatgt   3420

tatactgagt ttctacctct ttaactccac ctccaatttc tgtcaatcta caaacacaag   3480

tgtcgcctcg cagtgtttcg tatgaacaga atatcttgtg tttgcttttt gtcactt      3537


<210>  6871
<211>  474
<212>  PRT
<213>  Homo sapiens

<400>  6871

Met Gly Val Val Leu Ser Pro His Pro Ala Pro Ser Arg Arg Glu Pro 
1               5                   10                  15


Leu Ala Pro Leu Ala Pro Gly Thr Arg Pro Gly Trp Ser Pro Ala Val 
            20                  25                  30


Ser Gly Ser Ser Arg Ser Ala Leu Arg Pro Ser Thr Ala Gly Pro Gly 
        35                  40                  45


Pro Gly Pro Gly Thr Gly Trp Gly Gly Thr Ala Ala Ser Gly Arg Trp 
    50                  55                  60


Val Pro Ala Pro Ala Val His Cys Ala Ala Pro Arg Ala Ala Ala Gly 
65                  70                  75                  80


His Gln Gln His His Gly Pro Pro Leu Cys Ser Pro Asp Gly Ala Pro 
                85                  90                  95


Arg Arg Phe Lys Arg Arg Pro Gly Ser Pro Ala Pro Ala Ala Gln Thr 
            100                 105                 110


Gly Glu Thr Ser Leu Arg Glu Gln Pro His Gly Gly Pro Pro Ala Val 
        115                 120                 125


Pro Phe Val Val Pro Pro Thr Leu Gln Gly Arg Asp Trp Val Pro Leu 
    130                 135                 140


His Ser Gly Glu Trp Ala Asp Ala Pro Trp Asp Pro Cys Pro Ala Ser 
145                 150                 155                 160


Glu Leu Leu Pro His Thr Ser Ser Gly Gly Leu Gly Asp Ala Cys Met 
                165                 170                 175


Val Gly Ala Ile Asn Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys Ser 
            180                 185                 190


Glu Thr Asp Phe Pro Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser Val 
        195                 200                 205


Glu Tyr Glu Gln Glu Ala Glu Arg Leu Leu Val Gly Leu Ile Lys Ala 
    210                 215                 220


Gln His Leu Gln Ala Pro Ser Glu Thr Cys Ser Pro Leu Val Lys Leu 
225                 230                 235                 240


Tyr Leu Leu Pro Asp Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys Arg 
                245                 250                 255


Lys Thr Ser Asn Pro Gln Phe Asp Glu His Phe Ile Phe Gln Val Ser 
            260                 265                 270


Ser Lys Thr Ile Thr Gln Arg Val Leu Lys Phe Ser Val Tyr His Val 
        275                 280                 285


Asp Arg Gln Arg Lys His Gln Leu Leu Gly Gln Val Leu Phe Pro Leu 
    290                 295                 300


Lys Asn Glu Thr Leu Val Gly Asp Cys Arg Arg Val Ile Trp Arg Asp 
305                 310                 315                 320


Leu Glu Ala Glu Ser Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu Gln 
                325                 330                 335


Phe Cys Leu Ser Tyr Asn Asp Tyr Leu Ser Arg Leu Thr Val Val Val 
            340                 345                 350


Leu Arg Ala Lys Gly Leu Arg Leu Gln Glu Asp Arg Gly Ile Val Ser 
        355                 360                 365


Val Phe Val Lys Val Ser Leu Met Asn His Asn Lys Phe Val Lys Cys 
    370                 375                 380


Lys Lys Thr Ser Ala Val Leu Gly Ser Ile Asn Pro Val Tyr Asn Glu 
385                 390                 395                 400


Thr Phe Ser Phe Lys Ala Asp Ala Thr Glu Leu Asp Thr Ala Ser Leu 
                405                 410                 415


Ser Leu Thr Val Val Gln Asn Met Glu Gly Asp Lys Ser Gln Gln Leu 
            420                 425                 430


Gly Arg Val Val Val Gly Pro Tyr Met Tyr Thr Arg Gly Arg Glu Leu 
        435                 440                 445


Glu His Trp Asp Glu Met Leu Ser Lys Pro Lys Glu Leu Val Lys Arg 
    450                 455                 460


Trp His Ala Leu Cys Arg Thr Thr Glu Pro 
465                 470


<210>  6872
<211>  836
<212>  DNA
<213>  Homo sapiens

<400>  6872
gctttaagag acggcctggc agcccagccc cagccgccca gaccggcgag accagcctgc     60

gggagcagcc ccatggcggg ccaccagctg tgccattcgt ggtgccccca acccttcaag    120

gccgagattg ggtgcccctg cacagtggag agtgggccga tgccccatgg gacccctgcc    180

cggcatcaga gctgctgcct cacacctcca gcggcggcct tggagatgca tgtatggtgg    240

gggccatcaa cccagagctg tacaagttcc cggaggacaa aagtgagacc gacttccccg    300

acggctgcct ggggcggctg tggttctcgg tggaatatga gcaggaggct gagcggctgc    360

tggtgggctt gatcaaggca cagcacctgc aagccccctc ggagacctgc agccccctgg    420

tgaagctcta cctgctgccc gatgagcggc gcttcctcca atccaagacc aaacgcaaaa    480

cctccaaccc gcagtttgac gagcacttca tctttcaggt gtccagcaag accatcaccc    540

agagggtgct gaagttctcc gtctaccacg tggacaggca gaggaagcac cagctcctgg    600

gccaggtgct cttccccttg aagaatgaga ccctagtggg ggactgccgg cgtgtcatct    660

ggagagacct ggaggccgag agcctggagc ccccctcgga gtttggcgac ctccagttct    720

gcctcagcta caacgactac ctgagccgcc tgacggtggt tgtgctgcgt gccaagggcc    780

tccggctcca ggaggacaga ggcattggga agagcccccg actcaatggg cactga        836


<210>  6873
<211>  200
<212>  PRT
<213>  Homo sapiens

<400>  6873

Met Val Gly Ala Ile Asn Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys 
1               5                   10                  15


Ser Glu Thr Asp Phe Pro Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser 
            20                  25                  30


Val Glu Tyr Glu Gln Glu Ala Glu Arg Leu Leu Val Gly Leu Ile Lys 
        35                  40                  45


Ala Gln His Leu Gln Ala Pro Ser Glu Thr Cys Ser Pro Leu Val Lys 
    50                  55                  60


Leu Tyr Leu Leu Pro Asp Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys 
65                  70                  75                  80


Arg Lys Thr Ser Asn Pro Gln Phe Asp Glu His Phe Ile Phe Gln Val 
                85                  90                  95


Ser Ser Lys Thr Ile Thr Gln Arg Val Leu Lys Phe Ser Val Tyr His 
            100                 105                 110


Val Asp Arg Gln Arg Lys His Gln Leu Leu Gly Gln Val Leu Phe Pro 
        115                 120                 125


Leu Lys Asn Glu Thr Leu Val Gly Asp Cys Arg Arg Val Ile Trp Arg 
    130                 135                 140


Asp Leu Glu Ala Glu Ser Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu 
145                 150                 155                 160


Gln Phe Cys Leu Ser Tyr Asn Asp Tyr Leu Ser Arg Leu Thr Val Val 
                165                 170                 175


Val Leu Arg Ala Lys Gly Leu Arg Leu Gln Glu Asp Arg Gly Ile Gly 
            180                 185                 190


Lys Ser Pro Arg Leu Asn Gly His 
        195                 200


<210>  6874
<211>  1122
<212>  DNA
<213>  Homo sapiens

<400>  6874
actgcgcggc tccccgcgcc gcagctgggc accagcagca ccacggaccg cccctgtgct     60

cgcccgacgg cgccccgcgg cgctttaaga gacggcctgg cagcccagcc ccagccgccc    120

agaccggcga gaccagcctg cgggagcagc cccatggcgg agcagctggc cctggtgatt    180

gggggcacca tcggggggct gctgctgctg ctgttgatcg gggcaagctg ctgtctgtgg    240

agaaggttct gtgccaccct cacctatgag gagctgcctg ggacaccagc catggccacc    300

acagctgcct ccagtgggca gcgggacagg ccctgccagc cgcatgctag gacccaactg    360

agcaggccac cagctgtgcc attcgtggtg cccccaaccc ttcaaggccg agattgggtg    420

cccctgcaca gtggagagtg ggccgatgcc ccatgggacc cctgcccggc atcagagctg    480

ctgcctcaca cctccagcgg cggccttgga gatgcatgta tggtgggggc catcaaccca    540

gagctgtaca agttcccgga ggacaaaagt gagaccgact tccccgacgg ctgcctgggg    600

cggctgtggt tctcggtgga atatgagcag gaggctgagc ggctgctggt gggcttgatc    660

aaggcacagc acctgcaagc cccctcggag acctgcagcc ccctggtgaa gctctacctg    720

ctgcccgatg agcggcgctt cctccaatcc aagaccaaac gcaaaacctc caacccgcag    780

tttgacgagc acttcatctt tcaggtgtcc agcaagacca tcacccagag ggtgctgaag    840

ttctccgtct accacgtgga caggcagagg aagcaccagc tcctgggcca ggtgctcttc    900

cccttgaaga atgagaccct agtgggggac tgccggcgtg tcatctggag agacctggag    960

gccgagagcc tggagccccc ctcggagttt ggcgacctcc agttctgcct cagctacaac   1020

gactacctga gccgcctgac ggtggttgtg ctgcgtgcca agggcctccg gctccaggag   1080

gacagaggca ttgggaagag cccccgactc aatgggcact ga                      1122


<210>  6875
<211>  322
<212>  PRT
<213>  Homo sapiens

<400>  6875

Met Ala Glu Gln Leu Ala Leu Val Ile Gly Gly Thr Ile Gly Gly Leu 
1               5                   10                  15


Leu Leu Leu Leu Leu Ile Gly Ala Ser Cys Cys Leu Trp Arg Arg Phe 
            20                  25                  30


Cys Ala Thr Leu Thr Tyr Glu Glu Leu Pro Gly Thr Pro Ala Met Ala 
        35                  40                  45


Thr Thr Ala Ala Ser Ser Gly Gln Arg Asp Arg Pro Cys Gln Pro His 
    50                  55                  60


Ala Arg Thr Gln Leu Ser Arg Pro Pro Ala Val Pro Phe Val Val Pro 
65                  70                  75                  80


Pro Thr Leu Gln Gly Arg Asp Trp Val Pro Leu His Ser Gly Glu Trp 
                85                  90                  95


Ala Asp Ala Pro Trp Asp Pro Cys Pro Ala Ser Glu Leu Leu Pro His 
            100                 105                 110


Thr Ser Ser Gly Gly Leu Gly Asp Ala Cys Met Val Gly Ala Ile Asn 
        115                 120                 125


Pro Glu Leu Tyr Lys Phe Pro Glu Asp Lys Ser Glu Thr Asp Phe Pro 
    130                 135                 140


Asp Gly Cys Leu Gly Arg Leu Trp Phe Ser Val Glu Tyr Glu Gln Glu 
145                 150                 155                 160


Ala Glu Arg Leu Leu Val Gly Leu Ile Lys Ala Gln His Leu Gln Ala 
                165                 170                 175


Pro Ser Glu Thr Cys Ser Pro Leu Val Lys Leu Tyr Leu Leu Pro Asp 
            180                 185                 190


Glu Arg Arg Phe Leu Gln Ser Lys Thr Lys Arg Lys Thr Ser Asn Pro 
        195                 200                 205


Gln Phe Asp Glu His Phe Ile Phe Gln Val Ser Ser Lys Thr Ile Thr 
    210                 215                 220


Gln Arg Val Leu Lys Phe Ser Val Tyr His Val Asp Arg Gln Arg Lys 
225                 230                 235                 240


His Gln Leu Leu Gly Gln Val Leu Phe Pro Leu Lys Asn Glu Thr Leu 
                245                 250                 255


Val Gly Asp Cys Arg Arg Val Ile Trp Arg Asp Leu Glu Ala Glu Ser 
            260                 265                 270


Leu Glu Pro Pro Ser Glu Phe Gly Asp Leu Gln Phe Cys Leu Ser Tyr 
        275                 280                 285


Asn Asp Tyr Leu Ser Arg Leu Thr Val Val Val Leu Arg Ala Lys Gly 
    290                 295                 300


Leu Arg Leu Gln Glu Asp Arg Gly Ile Gly Lys Ser Pro Arg Leu Asn 
305                 310                 315                 320


Gly His 



<210>  6876
<211>  1966
<212>  DNA
<213>  Homo sapiens

<400>  6876
ggaatgctgc ctgctgcttt gcccagagtt ggccctgagt gttcctatca ggccccgttc     60

actctggggt ggattaaacc acctcctgga gggtgctgta tccccactgt gcaatggggg    120

tttgtgctgt gtgcattcct gcctggtcct tgagagttgc tgacaggtgg aacctgaggc    180

agcaggacag cctggcattg gccacgggac atcggccaca accatagcaa cttcggcatc    240

aaatggggca ggagagagaa cattaaggca gccatgagct ccagccgccc cgagccgggt    300

ccctgggcac ccctgagccc ccgccttcag cccctgtccc agagctcttc cagcctgctg    360

ggtgaaggcc gggaacagag gccagagctc cgcaagactg ccagcagcac cgtgtggcag    420

gcccagctgg gcgaggccag caccagaccc caggccccgg aggaagaggg gaacccgcct    480

gagagcatga agccagcacg ggcctctggc cccaaggcgc gacccagtgc tggaggccac    540

tggtggagca gcactgtggg caatgtgtcc accatgggcg gcagtgacct gtgtcgcctg    600

cgggccccta gtgctgctgc tatgcagagg agccattcag acctggtccg tagcacccag    660

atgcggggac acagtggtgc tcggaaggcc agtctcagct gctcagccct tggcagcagc    720

cctgtccaca gggctcagct gcagccaggt ggtacttctg gccagggtgg ccaggcccct    780

gcaggcctgg aaagggacct ggctcctgag gatgagactt ctaactcagc ctggatgctg    840

ggggcgagtc agttgtcagt gccaccacta gacctggggg acacaactgc ccacagcagc    900

agtgcccagg ctgagcccaa agctgctgaa cagctggcta ccaccacctg ccatgctctg    960

cccccagctg ctctactctg tggcatgagg gaggtgaggg ctggtggctg ctgccatgcc   1020

ctacctgcca cagggatcct ggcctttccc aaactagtgg cgtcagtgag cgagtctggg   1080

ctgcaggctc agcatggggt gaagatccac tgtaggttgt ctggggggct ccctgggcat   1140

tcccattgct gtgcccacct ttggggtccc gctgggttag tcccagagcc tggctctagg   1200

accaaagatg tgtggaccat gacctcagcc aatgacttgg cccctgcaga ggcatccccg   1260

ctgtcagccc aggatgctgg tgtgcaggcg gccccagtgg cggcctgcaa ggctgtggcc   1320

accagtccgt ccctggaagc gcctgcagcc ctgcatgtgt tcccagaggt aactctgggg   1380

tccagcctgg aggaggtgcc gtcccctgtg cgggatgtgc gatgggatgc tgagggcatg   1440

acatgggagg tgtacggagc tgcggtggac ctggaggtgc tcggtgtggc catccagaag   1500

cacctggaga tgcagtttga gcagctgcag cgggcgcccg ccagcgagga cagcctgtct   1560

gtggagggcc ggagggggcc actgcgggct gtcatgcagt ccctgcggcg ccccagctgc   1620

tgcggctgct ccggcgcggc ccccgagtga ggagctgtgg cccttggagc tggcctgggc   1680

ccactgactt agtcctagac ctgggccagg gacggtgggg gctccgtgcc ccctggaccc   1740

accggcagct gggcacatct ctcacctgaa tattggctgc ctccagacca caggactgca   1800

gcctggggct tccggcccta cacagctggg ctgttttctt aagggcttga tttccaaggg   1860

ccacatctct gcaccttccg ggctctgaac tttgagacag ggctttagca ctgtgcagag   1920

gggagatcct gagttttctg taaaaaatga ccttttgttc actcca                  1966


<210>  6877
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  6877

Met Gly Val Cys Ala Val Cys Ile Pro Ala Trp Ser Leu Arg Val Ala 
1               5                   10                  15


Asp Arg Trp Asn Leu Arg Gln Gln Asp Ser Leu Ala Leu Ala Thr Gly 
            20                  25                  30


His Arg Pro Gln Pro 
        35


<210>  6878
<211>  7719
<212>  DNA
<213>  Homo sapiens

<400>  6878
gtgggggaca atgaggatgc aggtacactg ggcaagaggg gattaaatgt caggcaggat     60

aggtctgatt gatggtactg ggtgggcatc ttatctcact gctgcaccgt ccccaggggt    120

acagaaaggt ctgaatgaat cccatgttcc ctagccctac agctgggcac gcagtagggg    180

ctcaggagat gctgtggaat caatgaccag atgctgaatg agtccctcat ggaaaaagct    240

gatgcatggg gcctctcctt gcccctggag ctagaggtag gagtcaggga accccagaga    300

catgccagct cagcaaggct aggccaagga ggatgggggt ggttgtggaa gcccagggtg    360

attctcagtg tcctctggtc attgctccct cgtcctgtga actttctctg agctcccact    420

ctgtaccaag gagaccctgt ccacagtgag ttggatactg ccagtcccag gaggaagtag    480

cccagtattg gcctgtccag ctgtgcccgt taagaggcca tagtgcttcc gtgctggttg    540

accaagagct gttatcccac agccccaccc cctagggctg cagtttcacc cccaaagccc    600

cagcagattt ggctctctcc cttcccctcc cacacaaacc agccagtaaa gagttgagag    660

ctgatagagt ggcggcctcc aggaccccac cctagggcag attctaactg cttgagactg    720

atgatgagat aatttgcagt gtcatccttg tgtctaatgt gagatgacct tgatttgaag    780

tgtctggtgt cttgtcactc actgccttgc atatggttct gaccagtcag gcaggctggg    840

actgaaggtg gctccctggt gaacctagca ctgtgggagt tcatagtaga atcggcttag    900

gtgctgccac ccaactcaac tccactccct ccctttctct cttctgcagg cagccatgag    960

ctccagccgc cccgagccgg gtccctgggc acccctgagc ccccgccttc agcccctgtc   1020

ccagagctct tccagcctgc tgggtgaagg ccgggaacag aggccagagc tccgcaagac   1080

tgccagcagc accgtgtggc aggcccagct gggcgaggcc agcaccagac cccaggcccc   1140

ggaggaagag gggaacccgc ctgagagcat gaagccagca cgggcctctg gccccaaggc   1200

gcgacccagt gctggaggcc actggtggag cagcactgtg ggcaatgtgt ccaccatggg   1260

cggcagtgac ctgtgtcgcc tgcgggcccc tagtgctgct gctatgcaga ggagccattc   1320

agacctggtc cgtagcaccc agatgcgggg acacagtggt gctcggaagg ccagtctcag   1380

ctgctcagcc cttggcagca gccctgtcca cagggctcag ctgcagccag gtggtacttc   1440

tggccagggt ggccaggccc ctgcaggcct ggaaagggac ctggctcctg aggatgagac   1500

ttctaactca gcctggatgc tgggggcgag tcagttgtca gtgccaccac tagacctggg   1560

ggacacaact gcccacagca gcagtgccca ggctgagccc aaagctgctg aacagctggc   1620

taccaccacc tgccatgctc tgcccccagc tgctctactc tgtggcatga gggaggtgag   1680

ggctggtggc tgctgccatg ccctacctgc cacagggatc ctggcctttc ccaaactagt   1740

ggcgtcagtg agcgagtctg ggctgcaggc tcagcatggg gtgaagatcc actgtaggtt   1800

gtctgggggg ctccctgggc attcccattg ctgtgcccac ctttggggtc ccgctgggtt   1860

agtcccagag cctggctcta ggaccaaaga tgtgtggacc atgacctcag ccaatgactt   1920

ggcccctgca gaggcatccc cgctgtcagc ccaggatgct ggtgtgcagg cggccccagt   1980

ggcggcctgc aaggctgtgg ccaccagtcc gtccctggaa gcgcctgcag ccctgcatgt   2040

gttcccagag gtaactctgg ggtccagcct ggaggaggtg ccgtcccctg tgcgggatgt   2100

gcgatgggat gctgagggca tgacatggga ggtgtacgga gctgcggtgg acctggaggt   2160

gctcggtgtg gccatccaga agcacctgga gatgcagttt gagcagctgc agcgggcgcc   2220

cgccagcgag gacagcctgt ctgtggaggg ccggaggggg ccactgcggg ctgtcatgca   2280

gtccctgcgg cgccccagct gctgcggctg ctccggcgcg gcccccgagt gaggagctgt   2340

ggcccttgga gctggcctgg gcccactgac ttagtcctag acctgggcca gggacggtgg   2400

gggctccgtg ccccctggac ccaccggcag ctgggcacat ctctcacctg aatattggct   2460

gcctccagac cacaggactg cagcctgggg cttccggccc tacacagctg ggctgttttc   2520

ttaagggctt gatttccaag ggccacatct ctgcaccttc cgggctctga actttgagac   2580

agggctttag cactgtgcag aggggagatc ctgagttttc tgtaaaaaat gaccttttgt   2640

tcactccacc ctcagaactc tgccatgttg cctcgtcaga ctcttggtgg ctttatttga   2700

aatcagtgct gagaaatagt gaattctcga catgaaatgt gaggccccag tgacagggac   2760

tgcccaggtc tttagggaag gggactgatg ttatcagagg cctcctgtgt gccacatact   2820

gtgcttgtcc tgtcttcacc tcttcatcct ggcaagcctt catttggcaa ggctgtagcc   2880

gatgtgcccc acgctggaca gcttgaagag gtgggactga gatccaaagc cagggccagc   2940

tgagccgtgg gtgttgccct gtagcatgtg cccggtccag tcagtgcagt catgtatgag   3000

gagaatttac tgagctcata ctctgtgctg ggttctgtgg attctgtggt gaatgagaca   3060

gaggctgccc ctgccctggc tgagctcatg gtgtgggttg gggatggcag gggaggatgc   3120

tgaccattac ggagggctgc caggcttcca gggtcattgt gtcagaggct ggcctgagga   3180

aggggagaat gggtggccac ctgccctaat ctcagttaca aagcctaaaa ttgcactatt   3240

ttcacctcat tctgtcggct gaaggatttc tccccagctg gtgcagtttg tggaaggagg   3300

gagggcagga atggaggggg acagggcagg agtttgccct ggccctgggg taggggctgt   3360

gaggctgtgg gggctcgctt gcccacatga cctgacctag gctaggcagt gggggccagg   3420

ggccttggag agacagaaac atgggctttg gcacagtctg acttcattgc ccaaagattt   3480

ctcgaggcct gtgaagaatg ggagtgggct tgtgttcttg tcctgggtct ttgtcttgaa   3540

gatcctaaga tcccgtgaca cagcccccca atccacccgt gtgagggacc agagggctag   3600

tgtggggtca tggcccacga cctggcctgt ttctggagcc tcttctgcac ctaggagccc   3660

aggaccccca cagtggtggc ttacttttcc ccatcctcaa ggacctggta ctcattgagg   3720

tggaaatgac tcatgcaaca gttggtgaat ttgtaaagca ggagtggcat ttcaacaggc   3780

cacaaggaca aagtgacaaa ggcgtgcgtc aggtcagatg cctcctgaag cccaacgatg   3840

gaccattctc acccgtaaac atgcctttcc catatgcata ggtgcacccc ttgggattct   3900

ggggctgtca gtccctttgt gtatggtgcc agggcaggca gctcacgttc tggggagtga   3960

cacatgggta tatgccatct tcatgcctgg ctccccatgg agtctccagg aaccccagcc   4020

tgttagggcc acatgagaga gaacaaatgg ctgtgggtgc atggggaggg acctttcaca   4080

cagggccata gctaagtagg gtcttgagga tgcaggggtt agacaggtgg gtggagagag   4140

ggcaggacct gcctggcaga tggaacagcc tggtcagata cttggatgtg cctgtcctgc   4200

ctgggccata atgagtttct gcagtggcgg ctcatttgga gcgtttgttg ggttgggagg   4260

tgaccagggg tccccattgt gaagatcctg atgtaaatga ggaaaggaac tttaagggaa   4320

ctgtggaagg ggttctgagg tgggaccaga tttcagttta gaaatatcca tttggcttcc   4380

agtggagatg tgccaggtga caccaaggag gggcctgttt aggggcaatg gagtgggcag   4440

ctgggggctg ggttcataca cgtgcacaca cacgcataca caggcacaca tgtgtgcaat   4500

ggatttgggg aggaggcatt tcaggatgct gaggtttcca gtttgagcaa gaggagggtg   4560

aggccactac ctgggtcaag gtgaatggca tgttcagcag gtgcagaaag ggccacctgc   4620

cacagggttt ggctgggacc agtgaaacct acttcatgaa gagactttct tctgtgtcac   4680

gtgcagattc ttatgcattc acgctggctg ggtgccactc tgtgctacct ccatgctgcc   4740

ctggcttgcc aggatggcag gccgggctgg gctcagccaa gctcccactc acctcatcgt   4800

cactgagatg agtatttgca gagcggtgct gaaatccaac acctgtgtct tggctggggc   4860

cccagatgat tctcctggct aaaccacgat ccttgtctcc ctagcccagt tgcacagctg   4920

ctgctgacag gtctacctga agtgactgca gcctcatttc tgattggaac tggagacccc   4980

tcccaacccc ctttgctgtg ccctctcctg gaacagccct gatgcctgca gtggtttagg   5040

gccccagagc atggccagcg gtttagttta cagatctcct ccccttggac tctagatttc   5100

tggccagact ttctgggtcc ctttcaggcc ctgctctggg aggtgttgga gttcactgtt   5160

gatgtgtttg tttggctttg aattcaaaac agatacaaat ttggaggtga gagctttgcc   5220

agaccccagc agggatgggg catcggtcct gactggtctt gtttattttg tcctggtaaa   5280

ttctgttctt tggagcataa accctggagt cctagagccc cttgcctcag caggaatccc   5340

ccctctgtct gctccagggg ctccctgctt ctgcccacct gctctccttc catggcattc   5400

aggacccccg acagctgaag cctctcttca tatagcttgt cccctctggg cctgcctgtc   5460

ttgtgtccag gacacaagac acgcatccct tgtctggccc caggctgcca tcactgtcac   5520

aagaaactca tagagtagag ctggtctgag gtcacagtgc tggtggtggt ggaaaagcag   5580

ggatggcctg ttccactgtg atcttacctc ctgtgtcacc tggattgggt ctctgtcccc   5640

ttagacatgc tagatcctaa ctttacaagg gctgaagggg tcttctacac gcaggtccca   5700

acactttggg ctggggttgg ccaccgtagc ttagtgggct aaagctggag tttgaatctg   5760

gatatatagg atccacacct atagccatgt gatcttgggc aagttacaag ccttgatcat   5820

cttcctcatc tgtaagatgg ggatgacaat ggtgcctcct tcacatgctt ggtgtggaga   5880

ttaaatagaa taacccaagt agtgcctggc actgagttag tgctcagcac acaggctggt   5940

agtgttgggc acccctctca tagccacatt caggggccac ctcttaccct gccagcttgg   6000

ctgtgatcac agcccacatc ccacttcctt aaaagtccct tgttcagagc ctctttccag   6060

gttcctcgcc ccacagcttt gcaccctgcc tgggacttgg ccctctggct ggggcttctg   6120

aaaatgtagt tcccagagtg cattgaggag ggctacccta gccctcacca ctcatcttgg   6180

gctgggttcc ccagaagctt ctgctgagat gaggatgctg gagttattag ggaggggaga   6240

gcaagttaag ggaggggcag aaggcaaggc agggtgtgat ttcagtccaa gtcagaccct   6300

aaaggggagc cctggatgca gtcccacctc agagtaagga ctacccaggg gtgaagatgt   6360

agcctccagg cacttctgct ctctggcagg caggctagga agctctagga gccccagggt   6420

aggtttctgc tggagtcgta gggcctattt tgggggaagt tgtgcacaga aaccaccaga   6480

gggagtcaca ggcatctggg ggtgcaccca ttgacatttg catccatgtc atgccaagct   6540

tgtagcccac aaatgcccaa cccttttctc catgcattgc tctgtctcag ttttgttcac   6600

gccaagcagc cttggttagt taaatgcaga gcttggcatt tgcccatgtt aaattccttc   6660

tcctttttca ttctggcctg gcctggtttt gccatctgaa gctatgacaa gtcctttatc   6720

agttttcatc caacttgtca ggcagggcag ggctggtatg aagcccagga catatcactg   6780

ggacatccca taggtctgtg agattcccag gtccctccaa atccacacgg tcatcatggg   6840

caaattagtt taagtctgat ctgttaagat ccagatctct cacaccaaca gcacacaccc   6900

ctttttccca tggccatgga aggagggtag catagcctga ctcgagtcct cgttctcagc   6960

agaactggtt ctgtggtggc cacttccctt tctcaacttt tacctacttc tgtttaatag   7020

gttgttctgc aagtctgaga gcaacagcaa gcttagaagt gtggactcag cctggtacag   7080

tggctcatgc ctgtaatccc agcactttgg gaggctgagg tgggctgact gcttgagctc   7140

aggagttcga aaccagcttg ggcagcatgg agaaatccca tctctacaaa aaatacaaaa   7200

attagctggg catggtggtg tgcatctgta gcctcagcta ctcagggggt tgaggtggga   7260

agatggcttg agcccaggag gtggaggttg cagtgagccg agatagtgcc actgtgctcc   7320

agcctggatg acggagccag accctgtttc aaaaaaagaa aaagacaaga aagaagtatg   7380

gactctacct tcttgccctt gtggagattg ggaactgcct gcccttggcc tctttcctgt   7440

ccatcttgta ttatgaaagg ctgtttctgg cacacccggg ctcctctgtg tggtttctgg   7500

gaagtgactg agggtcaggg gaatggagcc cctctgcagc cggccgctgg taccttccct   7560

attgaaccct tctttaggtt tgctcactct ttttgatggg tgtctttcca aagctggctg   7620

gggacctccc tgattgagag acatggggcc agttctgttg ctgtggctac acgggaataa   7680

taaagcagaa gaacacctga ggaaagctga tgtttacta                          7719


<210>  6879
<211>  458
<212>  PRT
<213>  Homo sapiens

<400>  6879

Met Ser Ser Ser Arg Pro Glu Pro Gly Pro Trp Ala Pro Leu Ser Pro 
1               5                   10                  15


Arg Leu Gln Pro Leu Ser Gln Ser Ser Ser Ser Leu Leu Gly Glu Gly 
            20                  25                  30


Arg Glu Gln Arg Pro Glu Leu Arg Lys Thr Ala Ser Ser Thr Val Trp 
        35                  40                  45


Gln Ala Gln Leu Gly Glu Ala Ser Thr Arg Pro Gln Ala Pro Glu Glu 
    50                  55                  60


Glu Gly Asn Pro Pro Glu Ser Met Lys Pro Ala Arg Ala Ser Gly Pro 
65                  70                  75                  80


Lys Ala Arg Pro Ser Ala Gly Gly His Trp Trp Ser Ser Thr Val Gly 
                85                  90                  95


Asn Val Ser Thr Met Gly Gly Ser Asp Leu Cys Arg Leu Arg Ala Pro 
            100                 105                 110


Ser Ala Ala Ala Met Gln Arg Ser His Ser Asp Leu Val Arg Ser Thr 
        115                 120                 125


Gln Met Arg Gly His Ser Gly Ala Arg Lys Ala Ser Leu Ser Cys Ser 
    130                 135                 140


Ala Leu Gly Ser Ser Pro Val His Arg Ala Gln Leu Gln Pro Gly Gly 
145                 150                 155                 160


Thr Ser Gly Gln Gly Gly Gln Ala Pro Ala Gly Leu Glu Arg Asp Leu 
                165                 170                 175


Ala Pro Glu Asp Glu Thr Ser Asn Ser Ala Trp Met Leu Gly Ala Ser 
            180                 185                 190


Gln Leu Ser Val Pro Pro Leu Asp Leu Gly Asp Thr Thr Ala His Ser 
        195                 200                 205


Ser Ser Ala Gln Ala Glu Pro Lys Ala Ala Glu Gln Leu Ala Thr Thr 
    210                 215                 220


Thr Cys His Ala Leu Pro Pro Ala Ala Leu Leu Cys Gly Met Arg Glu 
225                 230                 235                 240


Val Arg Ala Gly Gly Cys Cys His Ala Leu Pro Ala Thr Gly Ile Leu 
                245                 250                 255


Ala Phe Pro Lys Leu Val Ala Ser Val Ser Glu Ser Gly Leu Gln Ala 
            260                 265                 270


Gln His Gly Val Lys Ile His Cys Arg Leu Ser Gly Gly Leu Pro Gly 
        275                 280                 285


His Ser His Cys Cys Ala His Leu Trp Gly Pro Ala Gly Leu Val Pro 
    290                 295                 300


Glu Pro Gly Ser Arg Thr Lys Asp Val Trp Thr Met Thr Ser Ala Asn 
305                 310                 315                 320


Asp Leu Ala Pro Ala Glu Ala Ser Pro Leu Ser Ala Gln Asp Ala Gly 
                325                 330                 335


Val Gln Ala Ala Pro Val Ala Ala Cys Lys Ala Val Ala Thr Ser Pro 
            340                 345                 350


Ser Leu Glu Ala Pro Ala Ala Leu His Val Phe Pro Glu Val Thr Leu 
        355                 360                 365


Gly Ser Ser Leu Glu Glu Val Pro Ser Pro Val Arg Asp Val Arg Trp 
    370                 375                 380


Asp Ala Glu Gly Met Thr Trp Glu Val Tyr Gly Ala Ala Val Asp Leu 
385                 390                 395                 400


Glu Val Leu Gly Val Ala Ile Gln Lys His Leu Glu Met Gln Phe Glu 
                405                 410                 415


Gln Leu Gln Arg Ala Pro Ala Ser Glu Asp Ser Leu Ser Val Glu Gly 
            420                 425                 430


Arg Arg Gly Pro Leu Arg Ala Val Met Gln Ser Leu Arg Arg Pro Ser 
        435                 440                 445


Cys Cys Gly Cys Ser Gly Ala Ala Pro Glu 
    450                 455


<210>  6880
<211>  1800
<212>  DNA
<213>  Homo sapiens

<400>  6880
gggcacagga gtgcggccgg gggcggggcc gagtgggccc cggtacgaac cctccgggaa     60

gccgggcgcg ctgcctgccc ttggcccggg gcgcagagcg tcacactgga tctggggagc    120

atcctacccc cactgtggac ctcagtctcc tcacctgaga catgggcggc cccatccgca    180

ccctgtaagc cgcaagccaa ggaggcgtca tccctcaagt gtatcactta gttcaagagt    240

cctggaatct tttcacatcc actatgaaca cctctcacct cctggccttg ctgctcccaa    300

aatctccaca aggtgaaaac agaagcaaac ccctgggcac cccatacaac ttctctgaac    360

attgccagga ttccgtggac gtgatggtct tcatcgtcac ttcctacagc attgagactg    420

tcgtgggggt cctgggtaac ctctgcctga tgtgtgtgac tgtgaggcag aaggagaaag    480

ccaacgtgac caacctgctt atcgccaacc tggccttctc tgacttcctc atgtgcctcc    540

tctgccagcc gctgaccgcc gtctacacca tcatggacta ctggatcttt ggagagaccc    600

tctgcaagat gtcggccttc atccagtgca tgtcggtgac ggtctccatc ctctcgctcg    660

tcctcgtggc cctggagagg catcagctca tcatcaaccc aacaggctgg aagcccagca    720

tctcacaggc ctacctgggg attgtgctca tctgggtcat tgcctgtgtc ctctccctgc    780

ccttcctggc caacagcatc ctggagaatg tcttccacaa gaaccactcc aaggctctgg    840

agttcctggc ggataaggtg gtctgtaccg agtcctggcc actggctcac caccgcacca    900

tctacaccac cttcctgctc ctcttccagt actgcctccc actgggcttc atcctggtct    960

gttatgcacg catctaccgg cgcctgcaga ggcaggggcg cgtgtttcac aagggcacct   1020

acagcttgcg agctgggcac atgaagcagg tcaatgtggt gctggtggtg atggtggtgg   1080

cctttgctgt gctctggctg cctctgcatg tgttcaacag cctggaagac tggcaccatg   1140

aggccatccc catctgccac gggaacctca tcttcttagt gtgccacttg cttgccatgg   1200

cctccacctg cgtcaaccca ttcatctatg gctttctcaa caccaacttc aagaaggaga   1260

tcaaggccct ggtgctgact tgccagcaga gcgcccccct ggaggagtcg gagcatctgc   1320

ccctgtccac agtacatacg gaagtctcca aagggtccct gaggctaagt ggcaggtcca   1380

atcccattta accaggtcta ggtcttctcc ctgccatgtc ccttgccagg ctcttccact   1440

tagctaagtg ggcacactgc aagctggggt ggcaccccag cattcctggc tttctggggt   1500

ccagataggc tggcaagagc tgtttttgca tccatttgca tcgtgaagac tggcattttg   1560

atacttcagc tgtttgttcc tgggagaatt ctgagcacag attccagagg tcacagtaag   1620

ccttgcagct tgagctgaaa gatgccagag ccggagatgt ctgctggcag caggcagggt   1680

tcattctggt gacacagcaa cagatgcctg gcctgggaac ccagggattt cacctccacc   1740

agtgagacca cggggccact gtggggtgag ggaaggagcg cttggagtca gagctctaga   1800


<210>  6881
<211>  375
<212>  PRT
<213>  Homo sapiens

<400>  6881

Met Asn Thr Ser His Leu Leu Ala Leu Leu Leu Pro Lys Ser Pro Gln 
1               5                   10                  15


Gly Glu Asn Arg Ser Lys Pro Leu Gly Thr Pro Tyr Asn Phe Ser Glu 
            20                  25                  30


His Cys Gln Asp Ser Val Asp Val Met Val Phe Ile Val Thr Ser Tyr 
        35                  40                  45


Ser Ile Glu Thr Val Val Gly Val Leu Gly Asn Leu Cys Leu Met Cys 
    50                  55                  60


Val Thr Val Arg Gln Lys Glu Lys Ala Asn Val Thr Asn Leu Leu Ile 
65                  70                  75                  80


Ala Asn Leu Ala Phe Ser Asp Phe Leu Met Cys Leu Leu Cys Gln Pro 
                85                  90                  95


Leu Thr Ala Val Tyr Thr Ile Met Asp Tyr Trp Ile Phe Gly Glu Thr 
            100                 105                 110


Leu Cys Lys Met Ser Ala Phe Ile Gln Cys Met Ser Val Thr Val Ser 
        115                 120                 125


Ile Leu Ser Leu Val Leu Val Ala Leu Glu Arg His Gln Leu Ile Ile 
    130                 135                 140


Asn Pro Thr Gly Trp Lys Pro Ser Ile Ser Gln Ala Tyr Leu Gly Ile 
145                 150                 155                 160


Val Leu Ile Trp Val Ile Ala Cys Val Leu Ser Leu Pro Phe Leu Ala 
                165                 170                 175


Asn Ser Ile Leu Glu Asn Val Phe His Lys Asn His Ser Lys Ala Leu 
            180                 185                 190


Glu Phe Leu Ala Asp Lys Val Val Cys Thr Glu Ser Trp Pro Leu Ala 
        195                 200                 205


His His Arg Thr Ile Tyr Thr Thr Phe Leu Leu Leu Phe Gln Tyr Cys 
    210                 215                 220


Leu Pro Leu Gly Phe Ile Leu Val Cys Tyr Ala Arg Ile Tyr Arg Arg 
225                 230                 235                 240


Leu Gln Arg Gln Gly Arg Val Phe His Lys Gly Thr Tyr Ser Leu Arg 
                245                 250                 255


Ala Gly His Met Lys Gln Val Asn Val Val Leu Val Val Met Val Val 
            260                 265                 270


Ala Phe Ala Val Leu Trp Leu Pro Leu His Val Phe Asn Ser Leu Glu 
        275                 280                 285


Asp Trp His His Glu Ala Ile Pro Ile Cys His Gly Asn Leu Ile Phe 
    290                 295                 300


Leu Val Cys His Leu Leu Ala Met Ala Ser Thr Cys Val Asn Pro Phe 
305                 310                 315                 320


Ile Tyr Gly Phe Leu Asn Thr Asn Phe Lys Lys Glu Ile Lys Ala Leu 
                325                 330                 335


Val Leu Thr Cys Gln Gln Ser Ala Pro Leu Glu Glu Ser Glu His Leu 
            340                 345                 350


Pro Leu Ser Thr Val His Thr Glu Val Ser Lys Gly Ser Leu Arg Leu 
        355                 360                 365


Ser Gly Arg Ser Asn Pro Ile 
    370                 375


<210>  6882
<211>  1956
<212>  DNA
<213>  Homo sapiens

<400>  6882
gggcacagga gtgcggccgg gggcggggcc gagtgggccc cggtacgaac cctccgggaa     60

gccgggcgcg ctgcctgccc ttggcccggg gcgcagagcg tcacactgga tctggggagc    120

atcctacccc cactgtggac ctcagtctcc tcacctgaga catgggcggc cccatccgca    180

ccctgtaagc cgcaagccaa ggagattcct ggcccccatc ctggattcac ttaactacat    240

ctcctggtgg aagggccctg ggatctgcac tttcaacatg cttctagaat gattctgatg    300

tttactgaag gttgagaact gcaaccctgt gggattaata atgactagag aatctgagag    360

gcgtcatccc tcaagtgtat cacttagttc aagagtcctg gaatcttttc acatccacta    420

tgaacacctc tcacctcctg gccttgctgc tcccaaaatc tccacaaggt gaaaacagaa    480

gcaaacccct gggcacccca tacaacttct ctgaacattg ccaggattcc gtggacgtga    540

tggtcttcat cgtcacttcc tacagcattg agactgtcgt gggggtcctg ggtaacctct    600

gcctgatgtg tgtgactgtg aggcagaagg agaaagccaa cgtgaccaac ctgcttatcg    660

ccaacctggc cttctctgac ttcctcatgt gcctcctctg ccagccgctg accgccgtct    720

acaccatcat ggactactgg atctttggag agaccctctg caagatgtcg gccttcatcc    780

agtgcatgtc ggtgacggtc tccatcctct cgctcgtcct cgtggccctg gagaggcatc    840

agctcatcat caacccaaca ggctggaagc ccagcatctc acaggcctac ctggggattg    900

tgctcatctg ggtcattgcc tgtgtcctct ccctgccctt cctggccaac agcatcctgg    960

agaatgtctt ccacaagaac cactccaagg ctctggagtt cctggcggat aaggtggtct   1020

gtaccgagtc ctggccactg gctcaccacc gcaccatcta caccaccttc ctgctcctct   1080

tccagtactg cctcccactg ggcttcatcc tggtctgtta tgcacgcatc taccggcgcc   1140

tgcagaggca ggggcgcgtg tttcacaagg gcacctacag cttgcgagct gggcacatga   1200

agcaggtcaa tgtggtgctg gtggtgatgg tggtggcctt tgctgtgctc tggctgcctc   1260

tgcatgtgtt caacagcctg gaagactggc accatgaggc catccccatc tgccacggga   1320

acctcatctt cttagtgtgc cacttgcttg ccatggcctc cacctgcgtc aacccattca   1380

tctatggctt tctcaacacc aacttcaaga aggagatcaa ggccctggtg ctgacttgcc   1440

agcagagcgc ccccctggag gagtcggagc atctgcccct gtccacagta catacggaag   1500

tctccaaagg gtccctgagg ctaagtggca ggtccaatcc catttaacca ggtctaggtc   1560

ttctccctgc catgtccctt gccaggctct tccacttagc taagtgggca cactgcaagc   1620

tggggtggca ccccagcatt cctggctttc tggggtccag ataggctggc aagagctgtt   1680

tttgcatcca tttgcatcgt gaagactggc attttgatac ttcagctgtt tgttcctggg   1740

agaattctga gcacagattc cagaggtcac agtaagcctt gcagcttgag ctgaaagatg   1800

ccagagccgg agatgtctgc tggcagcagg cagggttcat tctggtgaca cagcaacaga   1860

tgcctggcct gggaacccag ggatttcacc tccaccagtg agaccacggg gccactgtgg   1920

ggtgagggaa ggagcgcttg gagtcagagc tctaga                             1956


<210>  6883
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  6883

Met Thr Arg Glu Ser Glu Arg Arg His Pro Ser Ser Val Ser Leu Ser 
1               5                   10                  15


Ser Arg Val Leu Glu Ser Phe His Ile His Tyr Glu His Leu Ser Pro 
            20                  25                  30


Pro Gly Leu Ala Ala Pro Lys Ile Ser Thr Arg 
        35                  40


<210>  6884
<211>  1598
<212>  DNA
<213>  Homo sapiens

<400>  6884
aggcgtcatc cctcaagtgt atcacttagt tcaagagtcc tggaatcttt tcacatccac     60

tatgaacacc tctcacctcc tggccttgct gctcccaaaa tctccacaag gtgaaaacag    120

aagcaaaccc ctgggcaccc catacaactt ctctgaacat tgccaggatt ccgtggacgt    180

gatggtcttc atcgtcactt cctacagcat tgagactgtc gtgggggtcc tgggtaacct    240

ctgcctgatg tgtgtgactg tgaggcagaa ggagaaagcc aacgtgacca acctgcttat    300

cgccaacctg gccttctctg acttcctcat gtgcctcctc tgccagccgc tgaccgccgt    360

ctacaccatc atggactact ggatctttgg agagaccctc tgcaagatgt cggccttcat    420

ccagtgcatg tcggtgacgg tctccatcct ctcgctcgtc ctcgtggccc tggagaggca    480

tcagctcatc atcaacccaa caggctggaa gcccagcatc tcacaggcct acctggggat    540

tgtgctcatc tgggtcattg cctgtgtcct ctccctgccc ttcctggcca acagcatcct    600

ggagaatgtc ttccacaaga accactccaa ggctctggag ttcctggcgg ataaggtggt    660

ctgtaccgag tcctggccac tggctcacca ccgcaccatc tacaccacct tcctgctcct    720

cttccagtac tgcctcccac tgggcttcat cctggtctgt tatgcacgca tctaccggcg    780

cctgcagagg caggggcgcg tgtttcacaa gggcacctac agcttgcgag ctgggcacat    840

gaagcaggtc aatgtggtgc tggtggtgat ggtggtggcc tttgctgtgc tctggctgcc    900

tctgcatgtg ttcaacagcc tggaagactg gcaccatgag gccatcccca tctgccacgg    960

gaacctcatc ttcttagtgt gccacttgct tgccatggcc tccacctgcg tcaacccatt   1020

catctatggc tttctcaaca ccaacttcaa gaaggagatc aaggccctgg tgctgacttg   1080

ccagcagagc gcccccctgg aggagtcgga gcatctgccc ctgtccacag tacatacgga   1140

agtctccaaa gggtccctga ggctaagtgg caggtccaat cccatttaac caggtctagg   1200

tcttctccct gccatgtccc ttgccaggct cttccactta gctaagtggg cacactgcaa   1260

gctggggtgg caccccagca ttcctggctt tctggggtcc agataggctg gcaagagctg   1320

tttttgcatc catttgcatc gtgaagactg gcattttgat acttcagctg tttgttcctg   1380

ggagaattct gagcacagat tccagaggtc acagtaagcc ttgcagcttg agctgaaaga   1440

tgccagagcc ggagatgtct gctggcagca ggcagggttc attctggtga cacagcaaca   1500

gatgcctggc ctgggaaccc agggatttca cctccaccag tgagaccacg gggccactgt   1560

ggggtgaggg aaggagcgct tggagtcaga gctctaga                           1598


<210>  6885
<211>  375
<212>  PRT
<213>  Homo sapiens

<400>  6885

Met Asn Thr Ser His Leu Leu Ala Leu Leu Leu Pro Lys Ser Pro Gln 
1               5                   10                  15


Gly Glu Asn Arg Ser Lys Pro Leu Gly Thr Pro Tyr Asn Phe Ser Glu 
            20                  25                  30


His Cys Gln Asp Ser Val Asp Val Met Val Phe Ile Val Thr Ser Tyr 
        35                  40                  45


Ser Ile Glu Thr Val Val Gly Val Leu Gly Asn Leu Cys Leu Met Cys 
    50                  55                  60


Val Thr Val Arg Gln Lys Glu Lys Ala Asn Val Thr Asn Leu Leu Ile 
65                  70                  75                  80


Ala Asn Leu Ala Phe Ser Asp Phe Leu Met Cys Leu Leu Cys Gln Pro 
                85                  90                  95


Leu Thr Ala Val Tyr Thr Ile Met Asp Tyr Trp Ile Phe Gly Glu Thr 
            100                 105                 110


Leu Cys Lys Met Ser Ala Phe Ile Gln Cys Met Ser Val Thr Val Ser 
        115                 120                 125


Ile Leu Ser Leu Val Leu Val Ala Leu Glu Arg His Gln Leu Ile Ile 
    130                 135                 140


Asn Pro Thr Gly Trp Lys Pro Ser Ile Ser Gln Ala Tyr Leu Gly Ile 
145                 150                 155                 160


Val Leu Ile Trp Val Ile Ala Cys Val Leu Ser Leu Pro Phe Leu Ala 
                165                 170                 175


Asn Ser Ile Leu Glu Asn Val Phe His Lys Asn His Ser Lys Ala Leu 
            180                 185                 190


Glu Phe Leu Ala Asp Lys Val Val Cys Thr Glu Ser Trp Pro Leu Ala 
        195                 200                 205


His His Arg Thr Ile Tyr Thr Thr Phe Leu Leu Leu Phe Gln Tyr Cys 
    210                 215                 220


Leu Pro Leu Gly Phe Ile Leu Val Cys Tyr Ala Arg Ile Tyr Arg Arg 
225                 230                 235                 240


Leu Gln Arg Gln Gly Arg Val Phe His Lys Gly Thr Tyr Ser Leu Arg 
                245                 250                 255


Ala Gly His Met Lys Gln Val Asn Val Val Leu Val Val Met Val Val 
            260                 265                 270


Ala Phe Ala Val Leu Trp Leu Pro Leu His Val Phe Asn Ser Leu Glu 
        275                 280                 285


Asp Trp His His Glu Ala Ile Pro Ile Cys His Gly Asn Leu Ile Phe 
    290                 295                 300


Leu Val Cys His Leu Leu Ala Met Ala Ser Thr Cys Val Asn Pro Phe 
305                 310                 315                 320


Ile Tyr Gly Phe Leu Asn Thr Asn Phe Lys Lys Glu Ile Lys Ala Leu 
                325                 330                 335


Val Leu Thr Cys Gln Gln Ser Ala Pro Leu Glu Glu Ser Glu His Leu 
            340                 345                 350


Pro Leu Ser Thr Val His Thr Glu Val Ser Lys Gly Ser Leu Arg Leu 
        355                 360                 365


Ser Gly Arg Ser Asn Pro Ile 
    370                 375


<210>  6886
<211>  3414
<212>  DNA
<213>  Homo sapiens

<400>  6886
gaggtcgcgt cccccctcgt gaccagcaaa ctcctaaaag cggcccttgc cccagagccc     60

ctgtagcctc caaccggcag tcaggaggca gcgccgtctc agcgccgctt agtggcgcca    120

ggcgtgcctg gaaatccgct ttcgcagcgc cccctcgtag ccgcctccgg ccgcagaaag    180

gcgttccctg gacagagaag cgggcgcgcg ggggcgggcg cgcggggcct tgccggagaa    240

cctgactctc cgcagcagca gtggaagccg gagtgacgcg ttgtgttgaa caccagtttt    300

ctggagcgct gtgtgttctt aacagctgag cagtctgttt ctccaatcag gtttcaaagc    360

cacttcaact gcactggccc ctgtgggtca ctgctgcacc gccctgaccc atgtgggtcc    420

ctgaggagcg acctgccggg gccacctggc tggatgaaaa agacacacct tggacttaag    480

ccgtgagaaa aaaaaaactt catcagtaag aagaatgaat aaacagacta ggttgaatcc    540

atacaatgga atgttagcag acaataaaaa gaaaatgaac tactgatgcc ccctactgca    600

cagcagaagc tctgaatcgt gttcctgaat gaaagaagtc agagatgaaa agatgggcca    660

ggagtccagt ttctggaagg ccaagaatcg aagtagtaag ctgcagccgt tttccagaca    720

agcaggatgt ggggatgcag aagaattcag gactggaggg gcaaactccg atgtgactga    780

ggccccactg ccaaatagca gcatgctcag atagcaccca ggaatttggg gaaaaaaact    840

ggtgctcaca gctgcccagt taaggcacaa ctctcccgcc tgctgcaggg cttgtgaggt    900

gtatcagaac cttgaagaga tactctggga agaaaggcct tcccagactg cctctccgca    960

gcgctgtaag aatcagattt cttctatggg ggacttccag gtctcttcag cattttctca   1020

gtcatcactg tatccctgcc actcagtgaa ccacagcaac aactcccagc ttccagccga   1080

gaagcttgac cctgaagctg gcctcgattc tctacagaag tgaggccaca gagcacaggt   1140

gaagggccac ttacctggta tcatctctgg tctcagctct ggagaactag ctcctctgcc   1200

actgccacat cctgtccacc aagacctcct tgctgaaccc cacccccacc cggtgcctca   1260

ggaccctaac ttgtttgctg acctccatgt cctctcacca gatccagccc tggggagctg   1320

aacttcctct ggcccactgc cagctctgga tcagtccaca ccccagccag ccacagccca   1380

gccctgcctc tctctgtctc tctctcatgg ctgggttggc cttggccaat gctctctcta   1440

gagatcaaga cacaggcacc tctcttggtc tgttctggct gctgtgacaa aatgccttaa   1500

gctgggtggc ttataaacca cagaaattta tttctcactg ttctggaggc tgggaagtcc   1560

tacagactgg ggtactggcc tgcttgtttc ctcgtgaggg ctctcttcct gggttgcaga   1620

tggacatctc cctgatgtat cttcacatgg cagagagaga gagagagaga gagacagaaa   1680

gacagagaaa gagagagaga gagagagaga gcatgctctt tggtctcttc tggtaagggc   1740

ctaatcccgt catgaagaat ccccataact tcaactaaat ctaatcactt ctcaaaggct   1800

ccatctccac ataccatccc attgtgggtt agggtttcaa cataggaatt ctggaggcac   1860

acaaacgtgc agttcaaaac atgtggagac aagggggcaa ggactagaga gccctaccat   1920

cctcgttcaa acccttgaat caagcctgaa gtcaaagaac ttcctttgga gagccccatt   1980

ccatgagccg ataatttccc cattttgcca tcacccactt gagtttggga ttttccccca   2040

gttactgagt gcctgactga catgatgccc cccacagatg ggcctccctg cccccaatct   2100

cacctcctct gttagtttcc tggggttgcc acaacaaagc gttacaggca gagcggctaa   2160

aacgacagaa acttatggtc tcacagttct ggaggctgca agttcaaggt caaggtgtca   2220

gcagggttgg ttccttcgga aggctgtgca ggagcctgtt gggtgcctgt ccctcagctt   2280

ctagtggatt acttccatct tcagcatgcc ttggcttgta gaaggactac cctgaactct   2340

gccttcatgg tcacaacaca tcctccctgt gtgtgtttct gtgtccaaat ttccccttct   2400

tataaggaca ccagtcttat acggacaatg ctcaatgtat gaacctttgc caagggattg   2460

gattagggac ccactatatt ccagtatgac ctcatcttaa ctaattatac ctgcaatgac   2520

actgcttcca aagaaggcca catgatgagg taccgttggt taggaattca atatatgagt   2580

ttggggggac acagttcagc ccacaccacc tcctctgacc ctgaattgga tgctgtttct   2640

gctctgctta tgatcctctt gtcctcactg gcctcttggt ccagcaccca ctgaggcacc   2700

agctctgaga gagctcactg gcttcacaca ggtgcgacct gatggcgcct cacctcacac   2760

cccaaacatc cttctcatct ctgcaggacc tgctctgttt atgtccaggt atgttcagtg   2820

ttcctgtgtg tccccagagt gtggggaggt aatgctccat gtacgaacct ttgccaaggg   2880

aatatggaaa ccgatggatg agttcttacc tcttttttcg tccagacaaa ctgtcctaag   2940

atggttttaa gagataccga gtaatcagct gccagctcag tagcgcatct tcagattgac   3000

tctccctcct tccctgtctc cttccccata ttcttcatct tgttccctgg gatctttctc   3060

cctaataaag gaaaagctca tagacctctg ccccagcttc tgctttctgg ggaatgcagg   3120

ccaatccagc cacactactc tccctccatg taacctgacc atgccatccc cctgcttaaa   3180

agctttcagt gcttctccat tgcccataaa gctcatactt tctagctatg agcttcaagg   3240

ccacttggag gtcatctggc caactgtcct tcctgctaca acagtctaag tcataggctt   3300

tggaagacaa ctgattgggt ttcatctttg gctcttattg aaaatgtgga aaaaattatt   3360

tcacctctat aagcttcagt ttcttcatct atctgatctc aggattgagg gaag         3414


<210>  6887
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  6887

Met Lys Glu Val Arg Asp Glu Lys Met Gly Gln Glu Ser Ser Phe Trp 
1               5                   10                  15


Lys Ala Lys Asn Arg Ser Ser Lys Leu Gln Pro Phe Ser Arg Gln Ala 
            20                  25                  30


Gly Cys Gly Asp Ala Glu Glu Phe Arg Thr Gly Gly Ala Asn Ser Asp 
        35                  40                  45


Val Thr Glu Ala Pro Leu Pro Asn Ser Ser Met Leu Arg 
    50                  55                  60


<210>  6888
<211>  3083
<212>  DNA
<213>  Homo sapiens

<400>  6888
gaggtcgcgt cccccctcgt gaccagcaaa ctcctaaaag cggcccttgc cccagagccc     60

ctgtagcctc caaccggcag tcaggaggca gcgccgtctc agcgccgctt agtggcgcca    120

ggcgtgcctg gaaatccgct ttcgcagcgc cccctcgtag ccgcctccgg ccgcagaaag    180

gcgttccctg gacagagaag cgggcgcgcg ggggcgggcg cgcggggcct tgccggagaa    240

cctgactctc cgcagcagca gtggaagccg gagtgacgcg ttgtgttgaa caccagtttt    300

ctggagcgct gtgtgttctt aacagctgag cagtctgttt ctccaatcag gtttcaaagc    360

cacttcaact gcactggccc ctgtgggtca ctgctgcacc gccctgaccc atgtgggtcc    420

ctgaggagcg acctgccggg gccacctggc tggatgaaaa agacacacct tggacttaag    480

ccgtgagaaa aaaaaaactt catcagtaag aagaatgaat aaacagacta ggttgaatcc    540

atacaatgga atgttagcag acaataaaaa gaaaatgaac tactgatgcc ccctactgca    600

cagcagaagc tctgaatcgt gttcctgaat gaaagaagtc agagatgaaa agatgggcca    660

ggagtccagt ttctggaagg ccaagaatcg aagtagtaag ctgcagccgt tttccagaca    720

agcaggatgt ggggatgcag aagaattcag gactggaggg gcaaactccg atgtgactga    780

ggccccactg ccaaatagca gcatgctcag atagcaccca ggaatttggg gaaaaaaact    840

ggtgctcaca gctgcccagt taaggcacaa ctctcccgcc tgctgcaggg cttgtgaggt    900

gtatcagaac cttgaagaga tactctggga agaaaggcct tcccagactg cctctccgca    960

gcgctgtaag aatcagattt cttctatggg ggacttccag gtctcttcag cattttctca   1020

gtcatcactg tatccctgcc actcagtgaa ccacagcaac aactcccagc ttccagccga   1080

gaagcttgac cctgaagctg gcctcgattc tctacagaag tgaggccaca gagcacaggt   1140

gaagggccac ttacctggta tcatctctgg tctcagctct ggagaactag ctcctctgcc   1200

actgccacat cctgtccacc aagacctcct tgctgaaccc cacccccacc cggtgcctca   1260

ggaccctaac ttgtttgctg acctccatgt cctctcacca gatccagccc tggggagctg   1320

aacttcctct ggcccactgc cagctctgga tcagtccaca ccccagccag ccacagccca   1380

gccctgcctc tctctgtctc tctctcatgg ctgggttggc cttggccaat gctctctcta   1440

gagatcaaga cacaggcacc tctcttggtc tgttctggct gctgtgacaa aatgccttaa   1500

gctgggtggc ttataaacca cagaaattta tttctcactg ttctggaggc tgggaagtcc   1560

tacagactgg ggtactggcc tgcttgtttc ctcgtgaggg ctctcttcct gggttgcaga   1620

tggacatctc cctgatgtat cttcacatgg cagagagaga gagagagaga gagacagaaa   1680

gacagagaaa gagagagaga gagagagaga gcatgctctt tggtctcttc tggtaagggc   1740

ctaatcccgt catgaagaat ccccataact tcaactaaat ctaatcactt ctcaaaggct   1800

ccatctccac ataccatccc attgtgggtt agggtttcaa cataggaatt ctggaggcac   1860

acaaacgtgc agttcaaaac atgtggagac aagggggcaa ggactagaga gccctaccat   1920

cctcgttcaa acccttgaat caagcctgaa gtcaaagaac ttcctttgga gagccccatt   1980

ccatgagccg ataatttccc cattttgcca tcacccactt gagtttggga ttttccccca   2040

gttactgagt gcctgactga catgatgccc cccacagatg ggcctccctg cccccaatct   2100

cacctcctct gttagtttcc tggggttgcc acaacaaagc gttacaggca gagcggctaa   2160

aacgacagaa acttatggtc tcacagttct ggaggctgca agttcaaggt caaggtgtca   2220

gcagggttgg ttccttcgga aggctgtgca ggagcctgtt gggtgcctgt ccctcagctt   2280

ctagtggatt acttccatct tcagcatgcc ttggcttgta gaaggactac cctgaactct   2340

gccttcatgg tcacaacaca tcctccctgt gtgtgtttct gtgtccaaat ttccccttct   2400

tataaggaca ccagtcttat acggacaatg ctcaatgtat gaacctttgc caagggattg   2460

gattagggac ccactatatt ccagtatgac ctcatcttaa ctaattatac ctgcaatgac   2520

actgcttcca aagaaggcca catgatgagg taccgttggt taggaattca atatatgagt   2580

ttggggggac acagttcagc ccacaccacc tcctctgacc ctgaattgga tgctgtttct   2640

gctctgctta tgatcctctt gtcctcactg gcctcttggt ccagcaccca ctgaggcacc   2700

agctctgaga gagctcactg gcttcacaca ggtgcgacct gatggcgcct cacctcacac   2760

cccaaacatc cttctcatct ctgcaggacc tgctctgttt atgtccaggt atgttcagtg   2820

ttcctgtgtg tccccagagt gtggggaggt aatgctccat gtacgaacct ttgccaaggg   2880

aatatggaaa ccgatggatg agttcttacc tcttttttcg tccagacaaa ctgtcctaag   2940

atggttttaa gagataccga gtaatcagct gccagctcag tagcgcatct tcagattgac   3000

tctccctcct tccctgtctc cttccccata ttcttcatct tgttccctgg gatctttctc   3060

cctaataaag gaaaagctca tag                                           3083


<210>  6889
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  6889

Met Lys Glu Val Arg Asp Glu Lys Met Gly Gln Glu Ser Ser Phe Trp 
1               5                   10                  15


Lys Ala Lys Asn Arg Ser Ser Lys Leu Gln Pro Phe Ser Arg Gln Ala 
            20                  25                  30


Gly Cys Gly Asp Ala Glu Glu Phe Arg Thr Gly Gly Ala Asn Ser Asp 
        35                  40                  45


Val Thr Glu Ala Pro Leu Pro Asn Ser Ser Met Leu Arg 
    50                  55                  60


<210>  6890
<211>  881
<212>  DNA
<213>  Homo sapiens

<400>  6890
gaggtcgcgt cccccctcgt gaccagcaaa ctcctaaaag cggcccttgc cccagagccc     60

ctgtagcctc caaccggcag tcaggaggca gcgccgtctc agcgccgctt agtggcgcca    120

ggcgtgcctg gaaatccgct ttcgcagcgc cccctcgtag ccgcctccgg ccgcagaaag    180

gcgttccctg gacagagaag cgggcgcgcg ggggcgggcg cgcggggcct tgccggagaa    240

cctgactctc cgcagcagca gtggaagccg gagtgacgcg ttgtgttgaa caccagtttt    300

ctggagcgct gtgtgttctt aacagctgag cagtctgttt ctccaatcag gtttcaaagc    360

cacttcaact gcactggccc ctgtgggtca ctgctgcacc gccctgaccc atgtgggtcc    420

ctgaggagcg acctgccggg gccacctggc tggatgaaaa agacacacct tggacttaag    480

ccgtgagaaa aaaaaaactt catcagtaag aagaatgaat aaacagacta ggttgaatcc    540

atacaatgga atgttagcag acaataaaaa gaaaatgaac tactgatgcc ccctactgca    600

cagcagaagc tctgaatcgt gttcctgaat gaaagaagtc agagatgaaa agatgggcca    660

ggagtccagt ttctggaagg ccaagaatcg aagtagtaag ctgcagccgt tttccagaca    720

agcaggatgt ggggatgcag aagaattcag gactggaggg gcaaactccg taagcagggg    780

ctgtcacgat tcccatctcc ctctataaac ctctctcttt tcatgtcata ctgttccatg    840

ttatatgtaa ctgttttaaa gctacatact ggacaaaaag t                        881


<210>  6891
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  6891

Met Lys Glu Val Arg Asp Glu Lys Met Gly Gln Glu Ser Ser Phe Trp 
1               5                   10                  15


Lys Ala Lys Asn Arg Ser Ser Lys Leu Gln Pro Phe Ser Arg Gln Ala 
            20                  25                  30


Gly Cys Gly Asp Ala Glu Glu Phe Arg Thr Gly Gly Ala Asn Ser Val 
        35                  40                  45


Ser Arg Gly Cys His Asp Ser His Leu Pro Leu 
    50                  55


<210>  6892
<211>  1434
<212>  DNA
<213>  Homo sapiens

<400>  6892
tgtggtcact caggtcccat agactctaga ggtcaaaggg cctccgagca tttgagaatc     60

agagagggca agtaacttgg ctgatatcac atagcacgaa ggtggcagag ccaggattcc    120

acctgctggc ctcccagatg tctttcctgt tggaccctgc ttgctggcca ctcctggtgg    180

gggtcactcc accattagtg tgttcatcaa actgacagtt gtggtccaga tcccttgcct    240

ctggtgtgcc cagcacctta gctggcacct ccctcagcaa acccagcctt cgccatcctc    300

ccaagcatac ttcccagggc tgttttgtcc attacggtcc cagaatataa ggcctttggg    360

ttttttcagg gcctgtgaaa aggtttgaaa catgaaaaac acactggcag ttccaaaatt    420

ctcaaataaa actgtagaaa tgccttagga attaaatatg taataagatg tgaacacttc    480

attacacacc tacaattagt cacatgccta cgatatgtga ataatgtcag gtcagctagt    540

gaactgttat acagtaattg cgcatcactt atatagatat acacaaagtg cacttactga    600

cttggatgtg tgtgttcatt gtttgaagtg gcgtggatgg aggctccaaa agataaaaga    660

atgtagggga ggtgactctt caaatggccc tcacccaccc cttaccctca gctcacccac    720

catgaagctt ccccttccaa ggaggacaca cctcctttcc tagaacattc ttcagtgcca    780

caagctgctc agtcagccct gattctggag tctccagtga gcgaggccta tactttgcaa    840

aaccatgaaa ccaaggtggc tattggcggt tccagcagca gcagtagcta tggcagtggc    900

agattttaat taggaaacaa agcttagcag gagaggagag ccagagaaat gacagggaat    960

ctacaggtta cgacagattt gtgaactcag ccaagcacag tggtggcagg gcctagctgc   1020

tacaaagaag acatgtttta gacaaatact catgtgtatg ggcaaaaaac tcgaggactg   1080

tatttgtgac taactgtata acaggttatt ttagtttctg ttctgtggga agtgtaaagc   1140

attccagcta agggttttaa tataggtttt ttttttgcac ccatgctgtt gattgctaaa   1200

tgtaatagtc tgatcatgac gctgaataaa tgtcttttgt tttaatgtgc tgtgtaaagt   1260

tagtttactc tgaagctatc ttggtaaatt tccccaacag tgtgaagtta gaattccttc   1320

agggtgatgc caagttctat ttggaattta tatacaacct gcttgggtgg agaagccatt   1380

gtcttcagaa acctttggtg tagttgaact gatagttact gttgtgacct gaag         1434


<210>  6893
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  6893

Met Ser Gly Gln Leu Val Asn Cys Tyr Thr Val Ile Ala His His Leu 
1               5                   10                  15


Tyr Arg Tyr Thr Gln Ser Ala Leu Thr Asp Leu Asp Val Cys Val His 
            20                  25                  30


Cys Leu Lys Trp Arg Gly Trp Arg Leu Gln Lys Ile Lys Glu Cys Arg 
        35                  40                  45


Gly Gly Asp Ser Ser Asn Gly Pro His Pro Pro Leu Thr Leu Ser Ser 
    50                  55                  60


Pro Thr Met Lys Leu Pro Leu Pro Arg Arg Thr His Leu Leu Ser 
65                  70                  75


<210>  6894
<211>  1153
<212>  DNA
<213>  Homo sapiens

<400>  6894
atccaggtag cctcaccctg agtggcagcc tggctgggtg agttctaaaa atgcccaaga     60

cctccaagac taggtgagat ctgaagtaat gaaatgcctc cattcactaa aggcctgaaa    120

ttgtcctgac tgcctcagtc ccacggacca agaagagcct ttcaagctgt gatcccaata    180

cttgtggctg ctgtgagaat aaggaaagca gcctaggcct caagtggaag gatcagatgt    240

ttgtccttca tacctcagag agccttcatc caagtaagat gggtggtgag gagctgtgga    300

tgacagcatg aaggatgagg actgatgcag cagccataat tagattatag gtttccatgg    360

gatgtgccat gactgcttac aaatggggcc cagccatgga attgagttat caactaagct    420

gattcctgag gcacagatca tcctgtcctc cacaacatga ttaaagacta catgatgctc    480

aggaagacct ctgcagctgt gtgcttggaa gagtgtgttt ttcctgctaa agcataagaa    540

aaaagagacc agcaattatt atcttaggcc ttgcagcatc ctttctggtc ccacaagttt    600

gagaaggcag tggcgtggat ggaggctcca aaagataaaa gaatgtaggg gaggtgactc    660

ttcaaatggc cctcacccac cccttaccct cagctcaccc accatgaagc ttccccttcc    720

aaggaggaca cacctccttt cctagaacat tcttcagtgc cacaagctgc tcagtcagcc    780

ctgattctgg agtctccagt gagcgaggcc aggggtggcc ccagtgggat gagccacact    840

ccccacagca ctcagcctgg atgtggcact ggctgcacat agcaagaggc agctattgga    900

cacctgctcg ccacatgttc tgtcttatcc tcccagcaac accgagtgag ggagggagtg    960

ttaacccacc attcaccagg tttaccagag accaagccca ggatctctcc actgcacact   1020

tttaaaaggg tcctttcagc ttcccattaa agaagtttgt tcctttgttc ctcctctcct   1080

gttcttccta agacatcatc actgaaattt aagcttataa atttaaaatg aagtaaatct   1140

ataagggaaa agc                                                      1153


<210>  6895
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  6895

Met Trp His Trp Leu His Ile Ala Arg Gly Ser Tyr Trp Thr Pro Ala 
1               5                   10                  15


Arg His Met Phe Cys Leu Ile Leu Pro Ala Thr Pro Ser Glu Gly Gly 
            20                  25                  30


Ser Val Asn Pro Pro Phe Thr Arg Phe Thr Arg Asp Gln Ala Gln Asp 
        35                  40                  45


Leu Ser Thr Ala His Phe 
    50


<210>  6896
<211>  949
<212>  DNA
<213>  Homo sapiens

<400>  6896
aatacctcgg taagccctag gcctgagtgt gaggttgcag gcacttccat ggccccatgc     60

aggtgtctaa gttccctcgt ggtatttggc caaggggggc cctgtgtgat gccctagcgc    120

ggtgactacc cgtgttcctg gcccatgggc atcttccacg gaattctggg cttagcctgg    180

ggattcatgc gggcacatct ctgtgatctg ctctggagca ggatgtacat caggtctctc    240

agacctgagt ccctggtgcc tggcgctcag ccttgactga agtgcttggc ccaccctgct    300

gggccagcca gctcctgctc agggccacag ccctgtaacc acggcttcct ccccaggact    360

caggaattct cccactccgg aatgccttgc tgctggggta accaggtctt cacttgtgaa    420

acaggagtcg gccacctcag ccctgcgcct ggcctggtgg aacatgggtc accgccccaa    480

cctggggcag ccgccccatc ccaacgcagt tgctgccgct ctccatgcct ccctgtgccc    540

agctaaccgg gggacttgtc ccctgggaaa acctgggtac ccaggctgcc tttggtttca    600

gcccctactc ctcttcccgg gctgcctgtg ctccccggac ggcccctttc cccgggctgt    660

gttcacatcg gctgggaagg gtcccttgca gacagatctt ggacgaggtc gcgtcccccc    720

tcgtgaccag caaactccta aaagcggccc ttgccccaga gcccctgtag cctccaaccg    780

gcagtcagga ggcagcgccg tctcagcgcc gcttagtggc gccaggcgtg cctggaaatc    840

cgctttcgca gcgccccctc gtagccgcct ccggccgcag aaaggcgttc cctggacaga    900

gaagcgggcg cgcgggggcg ggcgcgcggg gccttgccgg agaacctga                949


<210>  6897
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  6897

Met Gly His Arg Pro Asn Leu Gly Gln Pro Pro His Pro Asn Ala Val 
1               5                   10                  15


Ala Ala Ala Leu His Ala Ser Leu Cys Pro Ala Asn Arg Gly Thr Cys 
            20                  25                  30


Pro Leu Gly Lys Pro Gly Tyr Pro Gly Cys Leu Trp Phe Gln Pro Leu 
        35                  40                  45


Leu Leu Phe Pro Gly Cys Leu Cys Ser Pro Asp Gly Pro Phe Pro Arg 
    50                  55                  60


Ala Val Phe Thr Ser Ala Gly Lys Gly Pro Leu Gln Thr Asp Leu Gly 
65                  70                  75                  80


Arg Gly Arg Val Pro Pro Arg Asp Gln Gln Thr Pro Lys Ser Gly Pro 
                85                  90                  95


Cys Pro Arg Ala Pro Val Ala Ser Asn Arg Gln Ser Gly Gly Ser Ala 
            100                 105                 110


Val Ser Ala Pro Leu Ser Gly Ala Arg Arg Ala Trp Lys Ser Ala Phe 
        115                 120                 125


Ala Ala Pro Pro Arg Ser Arg Leu Arg Pro Gln Lys Gly Val Pro Trp 
    130                 135                 140


Thr Glu Lys Arg Ala Arg Gly Gly Gly Arg Ala Gly Pro Cys Arg Arg 
145                 150                 155                 160


Thr 



<210>  6898
<211>  1419
<212>  DNA
<213>  Homo sapiens

<400>  6898
gatatcccct gaagttagtt ccacacccga aacccaagcc ctctggccac ttctgcccag     60

gaaatgagag agggcatgcg attcccttgg ccatgtggcc ccagctgaca tgagactggt    120

cagggatgaa ggtgagcagg aaggccctgc ctgtgaaatt cctggctgag ctgattgctg    180

ccattgctct agtaggaagt cttgttcctg gagcagtgag tattttgtgt ctagaatctg    240

atgtggcaaa ccaaacatac tgcagtttgg agcacttggc atcataaagg aagagttctg    300

ggcagtgggt gagaaggaat taagggagtg gacaccctaa gccaccaaag cttccctcct    360

aatgcttccc tggctgaagc acaggctcct tcccacatct ccctccctct aaaagcccca    420

gaacccaacc acacagatcc gtccatcact cagagatgga caggaaaggt gaggcaggat    480

tgttgatggc tgctgtcttg cccagggagc agggacgcgt gatgggaccc tgataagaaa    540

catcgtttca aggagcgaga ttgacttaaa tcttatcaaa tgtcacttca agaagatgta    600

cggcaagacc ctcagcagca tgatcatgga agacaccagc ggcgactaca agaacgccct    660

gctgagcctg gtgggcagcg acccctgagg cacagaagaa caagagcaaa gaccatgaag    720

ccagagtctc caggactcct cactcaacct cggccatgga cgcaggtcat ttcccagtgt    780

gagcacaatg ccaaccttag tgtttctcca gccagacaga tgcctcagca tgaagggctt    840

ggggacttgt ggatcattcc ttcctccctg caggagcttc ccaagctggt cacagagtct    900

cctgggcaca ggttatacag accccagccc cattcccatc tactgaaaca gggtctccac    960

aagaggggcc agggaatatg ggtttttaac aagcgtctta caaaacactt ctctatcatg   1020

cagccggaga gctggctggg agcccttttg ttttagaaca cacatccttc agcagctgag   1080

aaacgaacac gaatccatcc caaccgagat gccattaaca ttcatctaaa aatgttaggc   1140

tctaaatgga cgaaaaattc tctcgccatc ttaataacaa aataaactac aaattcctga   1200

cccaaggaca ctgtgttata agaggcgtgg gctcccctgg tggctgacca ggtcagctgc   1260

cctggccttg cacccctctg catgcagcac agaagggtgt gaccatgccc tcagcaccac   1320

tcttgtcccc actgaacggc aactgagact gggtacctgg agattctgaa gtgcctttgc   1380

tgtggttttc aaaataataa agatttgtat tcaactcaa                          1419


<210>  6899
<211>  158
<212>  PRT
<213>  Homo sapiens

<400>  6899

Met Ser Leu Gln Glu Asp Val Arg Gln Asp Pro Gln Gln His Asp His 
1               5                   10                  15


Gly Arg His Gln Arg Arg Leu Gln Glu Arg Pro Ala Glu Pro Gly Gly 
            20                  25                  30


Gln Arg Pro Leu Arg His Arg Arg Thr Arg Ala Lys Thr Met Lys Pro 
        35                  40                  45


Glu Ser Pro Gly Leu Leu Thr Gln Pro Arg Pro Trp Thr Gln Val Ile 
    50                  55                  60


Ser Gln Cys Glu His Asn Ala Asn Leu Ser Val Ser Pro Ala Arg Gln 
65                  70                  75                  80


Met Pro Gln His Glu Gly Leu Gly Asp Leu Trp Ile Ile Pro Ser Ser 
                85                  90                  95


Leu Gln Glu Leu Pro Lys Leu Val Thr Glu Ser Pro Gly His Arg Leu 
            100                 105                 110


Tyr Arg Pro Gln Pro His Ser His Leu Leu Lys Gln Gly Leu His Lys 
        115                 120                 125


Arg Gly Gln Gly Ile Trp Val Phe Asn Lys Arg Leu Thr Lys His Phe 
    130                 135                 140


Ser Ile Met Gln Pro Glu Ser Trp Leu Gly Ala Leu Leu Phe 
145                 150                 155


<210>  6900
<211>  1971
<212>  DNA
<213>  Homo sapiens

<400>  6900
ccacccctgg atctggcctg aacccaccaa gaatgaagtc tgccagcagg gaatagtgaa     60

gccatgcagt gctccgtcat gctgggcctt cctattcact tcaccttgaa gcctcgcatc    120

agtctcactt cccagatgag tcagggaggt tgagtaatga agccatactg caccatcaag    180

gcaggaagtg aacacatgcc tacctcactc aaagcccatg ctccttctgc agccctaagt    240

gaaaatgcca accttcccca cccagatgcc aagtctctga gcagtaccca tgggagcaag    300

catgggccca gtctctggac cagacgcccc caggtgcctt agtcctgtgg ggccaaactc    360

cacttgtcac atgggaattc aaaatgcagg gttcctgctg ataagtgtga gagagagggc    420

actctgaggc cagcagccac catcccatgg tgcttctgtg gagctgagag gctggatttt    480

tggtggaggt gtctctgggt tgagagccca gggcctgtcc tgagtctgag ctgcccttgg    540

atgggcttga gctggtgtct tcagacgagc cccacagtct ggtgcatttc acatcttacc    600

cttttgcctg cctgcttggg cctttggagc tgtgcccagt gccccgggct accttccctg    660

tcccacgcca cctgacacaa agcctctcac attgggaaag gcacggaaca aagaaatatg    720

ccaagccttg cacaacactg actcttaaga cctaaggcaa gacataaagt tgtaggcagt    780

gccacctacc agctccagac attaacacag ctttcttgtt tgccagtgaa atgcacccaa    840

aacctccaca gctactttgc agagagactc tactatgcca tgaagggagc agggacgcgt    900

gatgggaccc tgataagaaa catcgtttca aggagcgaga ttgacttaaa tcttatcaaa    960

tgtcacttca agaagatgta cggcaagacc ctcagcagca tgatcatgga gtggaactgt   1020

ctctgattca ttttccacat caatcctgca tgtagttgga agacaccagc ggcgactaca   1080

agaacgccct gctgagcctg gtgggcagcg acccctgagg cacagaagaa caagagcaaa   1140

gaccatgaag ccagagtctc caggactcct cactcaacct cggccatgga cgcaggttgg   1200

gtgtgagggg ggtcccagcc tttcagtctt ctatttccct atttccagtg ctttccagcc   1260

gggtttctga cccagagggt ggaaccggcc tggactcctc ttcccaactt cctccaggtc   1320

atttcccagt gtgagcacaa tgccaacctt agtgtttctc cagccagaca gatgcctcag   1380

catgaagggc ttggggactt gtggatcatt ccttcctccc tgcaggagct tcccaagctg   1440

gtcacagagt ctcctgggca caggttatac agaccccagc cccattccca tctactgaaa   1500

cagggtctcc acaagagggg ccagggaata tgggttttta acaagcgtct tacaaaacac   1560

ttctctatca tgcagccgga gagctggctg ggagcccttt tgttttagaa cacacatcct   1620

tcagcagctg agaaacgaac acgaatccat cccaaccgag atgccattaa cattcatcta   1680

aaaatgttag gctctaaatg gacgaaaaat tctctcgcca tcttaataac aaaataaact   1740

acaaattcct gacccaagga cactgtgtta taagaggcgt gggctcccct ggtggctgac   1800

caggtcagct gccctggcct tgcacccctc tgcatgcagc acagaagggt gtgaccatgc   1860

cctcagcacc actcttgtcc ccactgaacg gcaactgaga ctgggtacct ggagattctg   1920

aagtgccttt gctgtggttt tcaaaataat aaagatttgt attcaactca a            1971


<210>  6901
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  6901

Met Lys Gly Ala Gly Thr Arg Asp Gly Thr Leu Ile Arg Asn Ile Val 
1               5                   10                  15


Ser Arg Ser Glu Ile Asp Leu Asn Leu Ile Lys Cys His Phe Lys Lys 
            20                  25                  30


Met Tyr Gly Lys Thr Leu Ser Ser Met Ile Met Glu Trp Asn Cys Leu 
        35                  40                  45


<210>  6902
<211>  1460
<212>  DNA
<213>  Homo sapiens

<400>  6902
tcctggtgtg cctcctgcag gtgtcacagc ctaggctctt gggagtgcct tggtttggga     60

gtcccaacag ctccacccca gggagcagcc cttgaatagc gccacaagag tcaggggcag    120

cagggatgat gtgagcagct ttgtggaccc aggactggcc ctccaagacg cacaggatct    180

gtatgcggca ggcgagaaga ttcgtgggac tgatgagatg aaattcatca ccatcctgtg    240

cacgcgcagt gccactcacc tgctgagagt gtttgaagag tatgagaaaa ttgccaacaa    300

gagcattgag gacagcatca agagtgagac ccatggctca ctggaggagg ccatgctcac    360

tgtggtgaaa tgcacccaaa acctccacag ctactttgca gagagactct actatgccat    420

gaagggagca gggacgcgtg atgggaccct gataagaaac atcgtttcaa ggagcgagat    480

tgacttaaat cttatcaaat gtcacttcaa gaagatgtac ggcaagaccc tcagcagcat    540

gatcatggaa gacaccagcg gcgactacaa gaacgccctg ctgagcctgg tgggcagcga    600

cccctgaggc acagaagaac aagagcaaag accatgaagc cagagtctcc aggactcctc    660

actcaacctc ggccatggac gcaggttggg tgtgaggggg gtcccagcct ttcagtcttc    720

tatttcccta tttccagtgc tttccagccg ggtttctgac ccagagggtg gaaccggcct    780

ggactcctct tcccaacttc ctccaggtca tttcccagtg tgagcacaat gccaacctta    840

gtgtttctcc agccagacag atgcctcagc atgaagggct tggggacttg tggatcattc    900

cttcctccct gcaggagctt cccaagctgg tcacagagtc tcctgggcac aggttataca    960

gaccccagcc ccattcccat ctactgaaac agggtctcca caagaggggc cagggaatat   1020

gggtttttaa caagcgtctt acaaaacact tctctatcat gcagccggag agctggctgg   1080

gagccctttt gttttagaac acacatcctt cagcagctga gaaacgaaca cgaatccatc   1140

ccaaccgaga tgccattaac attcatctaa aaatgttagg ctctaaatgg acgaaaaatt   1200

ctctcgccat cttaataaca aaataaacta caaattcctg acccaaggac actgtgttat   1260

aagaggcgtg ggctcccctg gtggctgacc aggtcagctg ccctggcctt gcacccctct   1320

gcatgcagca cagaagggtg tgaccatgcc ctcagcacca ctcttgtccc cactgaacgg   1380

caactgagac tgggtacctg gagattctga agtgcctttg ctgtggtttt caaaataata   1440

aagatttgta ttcaactcaa                                               1460


<210>  6903
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  6903

Met Lys Phe Ile Thr Ile Leu Cys Thr Arg Ser Ala Thr His Leu Leu 
1               5                   10                  15


Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala Asn Lys Ser Ile Glu Asp 
            20                  25                  30


Ser Ile Lys Ser Glu Thr His Gly Ser Leu Glu Glu Ala Met Leu Thr 
        35                  40                  45


Val Val Lys Cys Thr Gln Asn Leu His Ser Tyr Phe Ala Glu Arg Leu 
    50                  55                  60


Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg Asp Gly Thr Leu Ile Arg 
65                  70                  75                  80


Asn Ile Val Ser Arg Ser Glu Ile Asp Leu Asn Leu Ile Lys Cys His 
                85                  90                  95


Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser Ser Met Ile Met Glu Asp 
            100                 105                 110


Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu Ser Leu Val Gly Ser Asp 
        115                 120                 125


Pro 



<210>  6904
<211>  2026
<212>  DNA
<213>  Homo sapiens

<400>  6904
tcaacaaggt ggggattaaa atccaggtct gacaaagccc ttgatctctc tgctgctctg     60

tagatcagct gatgtagcct ggtggctcct cgtagcaaca tgtgacctta gaaggaggca    120

catgtgagac gaagtcttta attcaggcat gcattcattc attgagtgcc aagtgacagg    180

tattttatgg tgatgccata ctcagagctt gcagtctagc tagcaatacc aatttcattt    240

tactgagagc ttatgatgtg cccagcactg cactgaatgc tgaattgagt cacacacaac    300

cccctaagca acgggatgaa gcaggagcac gtttctctcc gtgtaaccgg taaagatact    360

gatgctaaga gaagctaagg agctggccca agaaacccag ccagcacgtg gcaaggccca    420

cgcagaatcc agcccaagcc cctggaccca gccaccactc cgctgcctgc actcagatac    480

gaagccaagg agctgcatga cgccatgaag ggcttaggaa ccaaggaggg tgtcatcatt    540

gagatcctgg cctctcggac caagaaccag ctgcgggaga taatgaaggc gtatgaggaa    600

gactatgggt ccagcctgga ggaggacatc caagcagaca caagtggcta cctggagagg    660

atcctggtgt gcctcctgca gggcagcagg gatgatgtga gcagctttgt ggacccagga    720

ctggccctcc aagacgcaca ggatctgtat gcggcaggcg agaagattcg tgggactgat    780

gagatgaaat tcatcaccat cctgtgcacg cgcagtgcca ctcacctgct gagagtgttt    840

gaagagtatg agaaaattgc caacaagagc attgaggaca gcatcaagag tgagacccat    900

ggctcactgg aggaggccat gctcactgtg gtgaaatgca cccaaaacct ccacagctac    960

tttgcagaga gactctacta tgccatgaag ggagcaggga cgcgtgatgg gaccctgata   1020

agaaacatcg tttcaaggag cgagattgac ttaaatctta tcaaatgtca cttcaagaag   1080

atgtacggca agaccctcag cagcatgatc atggaagaca ccagcggcga ctacaagaac   1140

gccctgctga gcctggtggg cagcgacccc tgaggcacag aagaacaaga gcaaagacca   1200

tgaagccaga gtctccagga ctcctcactc aacctcggcc atggacgcag gttgggtgtg   1260

aggggggtcc cagcctttca gtcttctatt tccctatttc cagtgctttc cagccgggtt   1320

tctgacccag agggtggaac cggcctggac tcctcttccc aacttcctcc aggtcatttc   1380

ccagtgtgag cacaatgcca accttagtgt ttctccagcc agacagatgc ctcagcatga   1440

agggcttggg gacttgtgga tcattccttc ctccctgcag gagcttccca agctggtcac   1500

agagtctcct gggcacaggt tatacagacc ccagccccat tcccatctac tgaaacaggg   1560

tctccacaag aggggccagg gaatatgggt ttttaacaag cgtcttacaa aacacttctc   1620

tatcatgcag ccggagagct ggctgggagc ccttttgttt tagaacacac atccttcagc   1680

agctgagaaa cgaacacgaa tccatcccaa ccgagatgcc attaacattc atctaaaaat   1740

gttaggctct aaatggacga aaaattctct cgccatctta ataacaaaat aaactacaaa   1800

ttcctgaccc aaggacactg tgttataaga ggcgtgggct cccctggtgg ctgaccaggt   1860

cagctgccct ggccttgcac ccctctgcat gcagcacaga agggtgtgac catgccctca   1920

gcaccactct tgtccccact gaacggcaac tgagactggg tacctggaga ttctgaagtg   1980

cctttgctgt ggttttcaaa ataataaaga tttgtattca actcaa                  2026


<210>  6905
<211>  222
<212>  PRT
<213>  Homo sapiens

<400>  6905

Met Lys Gly Leu Gly Thr Lys Glu Gly Val Ile Ile Glu Ile Leu Ala 
1               5                   10                  15


Ser Arg Thr Lys Asn Gln Leu Arg Glu Ile Met Lys Ala Tyr Glu Glu 
            20                  25                  30


Asp Tyr Gly Ser Ser Leu Glu Glu Asp Ile Gln Ala Asp Thr Ser Gly 
        35                  40                  45


Tyr Leu Glu Arg Ile Leu Val Cys Leu Leu Gln Gly Ser Arg Asp Asp 
    50                  55                  60


Val Ser Ser Phe Val Asp Pro Gly Leu Ala Leu Gln Asp Ala Gln Asp 
65                  70                  75                  80


Leu Tyr Ala Ala Gly Glu Lys Ile Arg Gly Thr Asp Glu Met Lys Phe 
                85                  90                  95


Ile Thr Ile Leu Cys Thr Arg Ser Ala Thr His Leu Leu Arg Val Phe 
            100                 105                 110


Glu Glu Tyr Glu Lys Ile Ala Asn Lys Ser Ile Glu Asp Ser Ile Lys 
        115                 120                 125


Ser Glu Thr His Gly Ser Leu Glu Glu Ala Met Leu Thr Val Val Lys 
    130                 135                 140


Cys Thr Gln Asn Leu His Ser Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala 
145                 150                 155                 160


Met Lys Gly Ala Gly Thr Arg Asp Gly Thr Leu Ile Arg Asn Ile Val 
                165                 170                 175


Ser Arg Ser Glu Ile Asp Leu Asn Leu Ile Lys Cys His Phe Lys Lys 
            180                 185                 190


Met Tyr Gly Lys Thr Leu Ser Ser Met Ile Met Glu Asp Thr Ser Gly 
        195                 200                 205


Asp Tyr Lys Asn Ala Leu Leu Ser Leu Val Gly Ser Asp Pro 
    210                 215                 220


<210>  6906
<211>  1879
<212>  DNA
<213>  Homo sapiens

<400>  6906
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgtttgaaga gtatgagaaa attgccaaca    840

agagcattga ggacagcatc aagagtgaga cccatggctc actggaggag gccatgctca    900

ctgtggtgaa atgcacccaa aacctccaca gctactttgc agagagactc tactatgcca    960

tgaagggagc agggacgcgt gatgggaccc tgataagaaa catcgtttca aggagcgaga   1020

ttgacttaaa tcttatcaaa tgtcacttca agaagatgta cggcaagacc ctcagcagca   1080

tgatcatgga agacaccagc ggcgactaca agaacgccct gctgagcctg gtgggcagcg   1140

acccctgagg cacagaagaa caagagcaaa gaccatgaag ccagagtctc caggactcct   1200

cactcaacct cggccatgga cgcaggtcat ttcccagtgt gagcacaatg ccaaccttag   1260

tgtttctcca gccagacaga tgcctcagca tgaagggctt ggggacttgt ggatcattcc   1320

ttcctccctg caggagcttc ccaagctggt cacagagtct cctgggcaca ggttatacag   1380

accccagccc cattcccatc tactgaaaca gggtctccac aagaggggcc agggaatatg   1440

ggtttttaac aagcgtctta caaaacactt ctctatcatg cagccggaga gctggctggg   1500

agcccttttg ttttagaaca cacatccttc agcagctgag aaacgaacac gaatccatcc   1560

caaccgagat gccattaaca ttcatctaaa aatgttaggc tctaaatgga cgaaaaattc   1620

tctcgccatc ttaataacaa aataaactac aaattcctga cccaaggaca ctgtgttata   1680

agaggcgtgg gctcccctgg tggctgacca ggtcagctgc cctggccttg cacccctctg   1740

catgcagcac agaagggtgt gaccatgccc tcagcaccac tcttgtcccc actgaacggc   1800

aactgagact gggtacctgg agattctgaa gtgcctttgc tgtggttttc aaaataataa   1860

agatttgtat tcaactcaa                                                1879


<210>  6907
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  6907

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala 
    210                 215                 220


Asn Lys Ser Ile Glu Asp Ser Ile Lys Ser Glu Thr His Gly Ser Leu 
225                 230                 235                 240


Glu Glu Ala Met Leu Thr Val Val Lys Cys Thr Gln Asn Leu His Ser 
                245                 250                 255


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
            260                 265                 270


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
        275                 280                 285


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
    290                 295                 300


Ser Met Ile Met Glu Asp Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu 
305                 310                 315                 320


Ser Leu Val Gly Ser Asp Pro 
                325


<210>  6908
<211>  2001
<212>  DNA
<213>  Homo sapiens

<400>  6908
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgtttgaaga gtatgagaaa attgccaaca    840

agagcattga ggacagcatc aagagtgaga cccatggctc actggaggag gccatgctca    900

ctgtggtgaa atgcacccaa aacctccaca gctactttgc agagagactc tactatgcca    960

tgaagggagc agggacgcgt gatgggaccc tgataagaaa catcgtttca aggagcgaga   1020

ttgacttaaa tcttatcaaa tgtcacttca agaagatgta cggcaagacc ctcagcagca   1080

tgatcatgga agacaccagc ggcgactaca agaacgccct gctgagcctg gtgggcagcg   1140

acccctgagg cacagaagaa caagagcaaa gaccatgaag ccagagtctc caggactcct   1200

cactcaacct cggccatgga cgcaggttgg gtgtgagggg ggtcccagcc tttcagtctt   1260

ctatttccct atttccagtg ctttccagcc gggtttctga cccagagggt ggaaccggcc   1320

tggactcctc ttcccaactt cctccaggtc atttcccagt gtgagcacaa tgccaacctt   1380

agtgtttctc cagccagaca gatgcctcag catgaagggc ttggggactt gtggatcatt   1440

ccttcctccc tgcaggagct tcccaagctg gtcacagagt ctcctgggca caggttatac   1500

agaccccagc cccattccca tctactgaaa cagggtctcc acaagagggg ccagggaata   1560

tgggttttta acaagcgtct tacaaaacac ttctctatca tgcagccgga gagctggctg   1620

ggagcccttt tgttttagaa cacacatcct tcagcagctg agaaacgaac acgaatccat   1680

cccaaccgag atgccattaa cattcatcta aaaatgttag gctctaaatg gacgaaaaat   1740

tctctcgcca tcttaataac aaaataaact acaaattcct gacccaagga cactgtgtta   1800

taagaggcgt gggctcccct ggtggctgac caggtcagct gccctggcct tgcacccctc   1860

tgcatgcagc acagaagggt gtgaccatgc cctcagcacc actcttgtcc ccactgaacg   1920

gcaactgaga ctgggtacct ggagattctg aagtgccttt gctgtggttt tcaaaataat   1980

aaagatttgt attcaactca a                                             2001


<210>  6909
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  6909

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala 
    210                 215                 220


Asn Lys Ser Ile Glu Asp Ser Ile Lys Ser Glu Thr His Gly Ser Leu 
225                 230                 235                 240


Glu Glu Ala Met Leu Thr Val Val Lys Cys Thr Gln Asn Leu His Ser 
                245                 250                 255


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
            260                 265                 270


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
        275                 280                 285


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
    290                 295                 300


Ser Met Ile Met Glu Asp Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu 
305                 310                 315                 320


Ser Leu Val Gly Ser Asp Pro 
                325


<210>  6910
<211>  1905
<212>  DNA
<213>  Homo sapiens

<400>  6910
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgaaatgcac ccaaaacctc cacagctact    840

ttgcagagag actctactat gccatgaagg gagcagggac gcgtgatggg accctgataa    900

gaaacatcgt ttcaaggagc gagattgact taaatcttat caaatgtcac ttcaagaaga    960

tgtacggcaa gaccctcagc agcatgatca tggaagacac cagcggcgac tacaagaacg   1020

ccctgctgag cctggtgggc agcgacccct gaggcacaga agaacaagag caaagaccat   1080

gaagccagag tctccaggac tcctcactca acctcggcca tggacgcagg ttgggtgtga   1140

ggggggtccc agcctttcag tcttctattt ccctatttcc agtgctttcc agccgggttt   1200

ctgacccaga gggtggaacc ggcctggact cctcttccca acttcctcca ggtcatttcc   1260

cagtgtgagc acaatgccaa ccttagtgtt tctccagcca gacagatgcc tcagcatgaa   1320

gggcttgggg acttgtggat cattccttcc tccctgcagg agcttcccaa gctggtcaca   1380

gagtctcctg ggcacaggtt atacagaccc cagccccatt cccatctact gaaacagggt   1440

ctccacaaga ggggccaggg aatatgggtt tttaacaagc gtcttacaaa acacttctct   1500

atcatgcagc cggagagctg gctgggagcc cttttgtttt agaacacaca tccttcagca   1560

gctgagaaac gaacacgaat ccatcccaac cgagatgcca ttaacattca tctaaaaatg   1620

ttaggctcta aatggacgaa aaattctctc gccatcttaa taacaaaata aactacaaat   1680

tcctgaccca aggacactgt gttataagag gcgtgggctc ccctggtggc tgaccaggtc   1740

agctgccctg gccttgcacc cctctgcatg cagcacagaa gggtgtgacc atgccctcag   1800

caccactctt gtccccactg aacggcaact gagactgggt acctggagat tctgaagtgc   1860

ctttgctgtg gttttcaaaa taataaagat ttgtattcaa ctcaa                   1905


<210>  6911
<211>  295
<212>  PRT
<213>  Homo sapiens

<400>  6911

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Lys Cys Thr Gln Asn Leu His Ser 
    210                 215                 220


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
225                 230                 235                 240


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
                245                 250                 255


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
            260                 265                 270


Ser Met Ile Met Glu Asp Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu 
        275                 280                 285


Ser Leu Val Gly Ser Asp Pro 
    290                 295


<210>  6912
<211>  1716
<212>  DNA
<213>  Homo sapiens

<400>  6912
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgtttgaaga gtatgagaaa attgccaaca    840

agagcattga ggacagcatc aagagtgaga cccatggctc actggaggag gccatgctca    900

ctgtggtgaa atgcacccaa aacctccaca gctactttgc agagagactc tactatgcca    960

tgaagggagc agggacgcgt gatgggaccc tgataagaaa catcgtttca aggagcgaga   1020

ttgacttaaa tcttatcaaa tgtcacttca agaagatgta cggcaagacc ctcagcagca   1080

tgatcatgga agacaccagc ggcgactaca agaacgccct gctgagcctg gtgggcagcg   1140

acccctgagg cacagaagaa caagagcaaa gaccatgaag ccagagtctc caggactcct   1200

cactcaacct cggccatgga cgcagacaga tgcctcagca tgaagggctt ggggacttgt   1260

ggatcattcc ttcctccctg caggagcttc ccaagctggt cacagagtct cctgggcaca   1320

gccggagagc tggctgggag cccttttgtt ttagaacaca catccttcag cagctgagaa   1380

acgaacacga atccatccca accgagatgc cattaacatt catctaaaaa tgttaggctc   1440

taaatggacg aaaaattctc tcgccatctt aataacaaaa taaactacaa attcctgacc   1500

caaggacact gtgttataag aggcgtgggc tcccctggtg gctgaccagg tcagctgccc   1560

tggccttgca cccctctgca tgcagcacag aagggtgtga ccatgccctc agcaccactc   1620

ttgtccccac tgaacggcaa ctgagactgg gtacctggag attctgaagt gcctttgctg   1680

tggttttcaa aataataaag atttgtattc aactca                             1716


<210>  6913
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  6913

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala 
    210                 215                 220


Asn Lys Ser Ile Glu Asp Ser Ile Lys Ser Glu Thr His Gly Ser Leu 
225                 230                 235                 240


Glu Glu Ala Met Leu Thr Val Val Lys Cys Thr Gln Asn Leu His Ser 
                245                 250                 255


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
            260                 265                 270


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
        275                 280                 285


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
    290                 295                 300


Ser Met Ile Met Glu Asp Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu 
305                 310                 315                 320


Ser Leu Val Gly Ser Asp Pro 
                325


<210>  6914
<211>  1888
<212>  DNA
<213>  Homo sapiens

<400>  6914
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgtttgaaga gtatgagaaa attgccaaca    840

agagcattga ggacagcatc aagagtgaga cccatggctc actggaggag gccatgctca    900

ctgtggtgaa atgcacccaa aacctccaca gctactttgc agagagactc tactatgcca    960

tgaagggagc agggacgcgt gatgggaccc tgataagaaa catcgtttca aggagcgaga   1020

ttgacttaaa tcttatcaaa tgtcacttca agaagatgta cggcaagacc ctcagcagca   1080

tgatcatgga agacaccagc ggcgactaca agaacgccct gctgagcctg gtgggcagcg   1140

acccctgagg cacagaagaa caagagcaaa gaccatgaag ccagagtctc caggactcct   1200

cactcaacct cggccatgga cgcaggttgg gtgtgagggg ggtcccagcc tttcagtctt   1260

ctatttccct atttccagtg ctttccagcc gggtttctga cccagagggt ggaaccggcc   1320

tggactcctc ttcccaactt cctccaggtc atttcccagt gtgagcacaa tgccaacctt   1380

agtgtttctc cagccagaca gatgcctcag catgaagggc ttggggactt gtggatcatt   1440

ccttcctccc tgcaggagct tcccaagctg gtcacagagt ctcctgggca cagccggaga   1500

gctggctggg agcccttttg ttttagaaca cacatccttc agcagctgag aaacgaacac   1560

gaatccatcc caaccgagat gccattaaca ttcatctaaa aatgttaggc tctaaatgga   1620

cgaaaaattc tctcgccatc ttaataacaa aataaactac aaattcctga cccaaggaca   1680

ctgtgttata agaggcgtgg gctcccctgg tggctgacca ggtcagctgc cctggccttg   1740

cacccctctg catgcagcac agaagggtgt gaccatgccc tcagcaccac tcttgtcccc   1800

actgaacggc aactgagact gggtacctgg agattctgaa gtgcctttgc tgtggttttc   1860

aaaataataa agatttgtat tcaactca                                      1888


<210>  6915
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  6915

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala 
    210                 215                 220


Asn Lys Ser Ile Glu Asp Ser Ile Lys Ser Glu Thr His Gly Ser Leu 
225                 230                 235                 240


Glu Glu Ala Met Leu Thr Val Val Lys Cys Thr Gln Asn Leu His Ser 
                245                 250                 255


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
            260                 265                 270


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
        275                 280                 285


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
    290                 295                 300


Ser Met Ile Met Glu Asp Thr Ser Gly Asp Tyr Lys Asn Ala Leu Leu 
305                 310                 315                 320


Ser Leu Val Gly Ser Asp Pro 
                325


<210>  6916
<211>  1497
<212>  DNA
<213>  Homo sapiens

<400>  6916
gacggcaggc aggtgtggcg ctgccctggg cgggcttgca cccccacacc caagtgagcg     60

gcctgctcac tcctcagctg caggagccag acgtgtggag tcccagcaga ggccaacctg    120

tgtctcttca tctccctggg aaaggtgccc ccgaggtgaa agagatggcc tggtggaaat    180

cctggattga acaggagggt gtcacagtga agagcagctc ccacttcaac ccagaccctg    240

atgcagagac cctctaccaa gccatgaagg ggatcgggac caacgagcag gctatcatcg    300

atgtgctcac caagagaagc aacacgcagc ggcagcagat cgccaagtcc ttcaaggctc    360

agttcggcaa ggacctcact gagaccttga agtctgagct cagtggcaag tttgagaggc    420

tcattgtggc ccttatgtac ccgccataca gatacgaagc caaggagctg catgacgcca    480

tgaagggctt aggaaccaag gagggtgtca tcattgagat cctggcctct cggaccaaga    540

accagctgcg ggagataatg aaggcgtatg aggaagacta tgggtccagc ctggaggagg    600

acatccaagc agacacaagt ggctacctgg agaggatcct ggtgtgcctc ctgcagggca    660

gcagggatga tgtgagcagc tttgtggacc caggactggc cctccaagac gcacaggatc    720

tgtatgcggc aggcgagaag attcgtggga ctgatgagat gaaattcatc accatcctgt    780

gcacgcgcag tgccactcac ctgctgagag tgtttgaaga gtatgagaaa attgccaaca    840

agagcattga ggacagcatc aagagtgaga cccatggctc actggaggag gccatgctca    900

ctgtggtgaa atgcacccaa aacctccaca gctactttgc agagagactc tactatgcca    960

tgaagggagc agggacgcgt gatgggaccc tgataagaaa catcgtttca aggagcgaga   1020

ttgacttaaa tcttatcaaa tgtcacttca agaagatgta cggcaagacc ctcagcagca   1080

tgatcatggt aagcaggcat tcccaatgct gaggccagcc tgaaacccag acattcaggg   1140

aaacctggag gctgtggcca acactacgtg agcccctccc ttcccagtgg gcaccatgtg   1200

cttgcattca tgaccatgtg gtgtgtgcag ggaacagcag aggtcagtgt ggctggatcc   1260

caaggggaat ggggggcaga ggggagatgc agagaccagg gcacagaggc tcccctgtgt   1320

cccactcaga aagttggttt cacatttaag ttatggttgc tccttggaaa agacaccaaa   1380

tccttgcaga agaagccacc tctgaatagt caatgagatg aactagtccg gtaggaatcg   1440

ggcccaccgc tcaaatccag atttaagtag tcctggcggc caacttctaa ggagata      1497


<210>  6917
<211>  315
<212>  PRT
<213>  Homo sapiens

<400>  6917

Met Ala Trp Trp Lys Ser Trp Ile Glu Gln Glu Gly Val Thr Val Lys 
1               5                   10                  15


Ser Ser Ser His Phe Asn Pro Asp Pro Asp Ala Glu Thr Leu Tyr Gln 
            20                  25                  30


Ala Met Lys Gly Ile Gly Thr Asn Glu Gln Ala Ile Ile Asp Val Leu 
        35                  40                  45


Thr Lys Arg Ser Asn Thr Gln Arg Gln Gln Ile Ala Lys Ser Phe Lys 
    50                  55                  60


Ala Gln Phe Gly Lys Asp Leu Thr Glu Thr Leu Lys Ser Glu Leu Ser 
65                  70                  75                  80


Gly Lys Phe Glu Arg Leu Ile Val Ala Leu Met Tyr Pro Pro Tyr Arg 
                85                  90                  95


Tyr Glu Ala Lys Glu Leu His Asp Ala Met Lys Gly Leu Gly Thr Lys 
            100                 105                 110


Glu Gly Val Ile Ile Glu Ile Leu Ala Ser Arg Thr Lys Asn Gln Leu 
        115                 120                 125


Arg Glu Ile Met Lys Ala Tyr Glu Glu Asp Tyr Gly Ser Ser Leu Glu 
    130                 135                 140


Glu Asp Ile Gln Ala Asp Thr Ser Gly Tyr Leu Glu Arg Ile Leu Val 
145                 150                 155                 160


Cys Leu Leu Gln Gly Ser Arg Asp Asp Val Ser Ser Phe Val Asp Pro 
                165                 170                 175


Gly Leu Ala Leu Gln Asp Ala Gln Asp Leu Tyr Ala Ala Gly Glu Lys 
            180                 185                 190


Ile Arg Gly Thr Asp Glu Met Lys Phe Ile Thr Ile Leu Cys Thr Arg 
        195                 200                 205


Ser Ala Thr His Leu Leu Arg Val Phe Glu Glu Tyr Glu Lys Ile Ala 
    210                 215                 220


Asn Lys Ser Ile Glu Asp Ser Ile Lys Ser Glu Thr His Gly Ser Leu 
225                 230                 235                 240


Glu Glu Ala Met Leu Thr Val Val Lys Cys Thr Gln Asn Leu His Ser 
                245                 250                 255


Tyr Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Arg 
            260                 265                 270


Asp Gly Thr Leu Ile Arg Asn Ile Val Ser Arg Ser Glu Ile Asp Leu 
        275                 280                 285


Asn Leu Ile Lys Cys His Phe Lys Lys Met Tyr Gly Lys Thr Leu Ser 
    290                 295                 300


Ser Met Ile Met Val Ser Arg His Ser Gln Cys 
305                 310                 315


<210>  6918
<211>  1765
<212>  DNA
<213>  Homo sapiens

<400>  6918
tttctgcctt tttgtttccc tccggcgagt cggcgcgagg gtgaatttcc gtttccggcg     60

gtgtccaagc ggacctaagg agtcgcagtt gtgaacaggt ttggtgccgc gggctggggt    120

aggcggcggt tgggtccgtg gctctggggc actgggaaga tcgcgagtcg tgcgcatggg    180

aaggtcctcc cccggtcctc cgggtcatct ttgctcccga ggagcggcat atttcgcatc    240

tgcctgaggt tagagttact tgttattggt aaatagccac tatggagact aaggaccaga    300

agaaacacag aaagaaaaac ggtggaccca aagctgcaaa gaaaaagaag tggcatctgc    360

aggatctcca gctaggagac taagaaaatg cccagaagag aaatgccaat gcttttgcag    420

ttcagtctgc tgtgtggatg tctcgatcct ttcacaggac tctggatttg aagacacaaa    480

agcatcatat tccagtggtt gatggaactc cactagagcc gccaccaata ccggtagtgg    540

tgacggggcc tccaaagttg gaaagagcac tttgatataa tgcctcattc ggaacttcac    600

ctggcagaag ttcaccgaga tcagaggccc tgtgacgatc gtgtcaggta aaaagcgcag    660

actcaccatt attgaatgtg ggtgtgacat taacatgatg attgatctgg ctaaagtagc    720

agatctggtt gccaaactgt tctacctttc tggaatggtg catggagaat atcaaaacca    780

agaaatccac aatctgggcc attttattac agttatgaag tttaggcctc tcatggcaaa    840

cttttcaccc ttatatcctg gcagacagga tggaagattt gacaaacccg gaggatatcc    900

aaacaaacat caaatgtgac cggcaggtgt cactttatgg ttatttaaga ggagcacact    960

tcaaagataa aagccaaatt cacatgccag gtatctactg agcgtttcag tcaacaatac   1020

agctcgtgtt cgacaatatt ccttgatgac agcacagcca tccagcatta tcttacaatg   1080

acaataatat cgcactgaga agccttttag gaaaatcggg atggatgtga ggcatctttc   1140

tgtgaagaaa agcatcccag aagattctga ttttcacccc agctcaatca ttccaaactt   1200

tgctgctgat tgaaatcacc tgggaaacgt ttaccaagaa ccttgatgcc caaagccata   1260

cccaatacta attaaattaa aatgtctcat gtggaagatg aggcagatat taaagcttct   1320

caggcgattt taatgtgcag caaagtttga gagccactgc ttaatttgag tttaggacga   1380

gaaactgctc ctatttggtg ggaccttggg caagtcagtt ttaagtgtga ccttggagat   1440

acctcatcat atcacacaaa gagatgcaga tagatctttg agcatacctg atgaacagtt   1500

acactcattt gcgttcatgc cgtggaggaa gtggtgaagg aggtggtggg acatgccaag   1560

gagactggag agaaagccat tgctgaagcc ataaagaaag cccaggagtc aggggacaaa   1620

aagatgaagg aaatcaccga gacagtgacc aacacagtca caaatgccat cacccatgca   1680

gcagaaagtc tggacaaact tggacagtga gtgcacctgc taccacggcc cttccccagt   1740

ctcaataaaa agccatgaca tgtgt                                         1765


<210>  6919
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  6919

Met Met Ile Asp Leu Ala Lys Val Ala Asp Leu Val Ala Lys Leu Phe 
1               5                   10                  15


Tyr Leu Ser Gly Met Val His Gly Glu Tyr Gln Asn Gln Glu Ile His 
            20                  25                  30


Asn Leu Gly His Phe Ile Thr Val Met Lys Phe Arg Pro Leu Met Ala 
        35                  40                  45


Asn Phe Ser Pro Leu Tyr Pro Gly Arg Gln Asp Gly Arg Phe Asp Lys 
    50                  55                  60


Pro Gly Gly Tyr Pro Asn Lys His Gln Met 
65                  70


<210>  6920
<211>  413
<212>  DNA
<213>  Homo sapiens

<400>  6920
gcaggagcgc ccatggctgc tgctgtacag cctgctgagg tgactgttga agttggtgag     60

gacctccaca tgcaccaggt tcgtgaccgg gagatgcctg aagctttgga gtttaacctt    120

tctgccaatc cagaggcaag cacaatattc cagaggaact ctcaaacaga tgctttggag    180

tttaactctt ctgccaatcc agaggcaagc acaatattcc agaggaactc tcaaacagat    240

gttgtagaaa taagaagaag caactgtaca aaccatgtat ctactgagcg tttcagtcaa    300

caatacagct cgtgttcgac aatattcctt gatgacagca cagccatcca gcattatctt    360

acaatgacaa taatatctgt gaccttggag atacctcatc atatcacaca aag           413


<210>  6921
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  6921

Met Ala Ala Ala Val Gln Pro Ala Glu Val Thr Val Glu Val Gly Glu 
1               5                   10                  15


Asp Leu His Met His Gln Val Arg Asp Arg Glu Met Pro Glu Ala Leu 
            20                  25                  30


Glu Phe Asn Leu Ser Ala Asn Pro Glu Ala Ser Thr Ile Phe Gln Arg 
        35                  40                  45


Asn Ser Gln Thr Asp Ala Leu Glu Phe Asn Ser Ser Ala Asn Pro Glu 
    50                  55                  60


Ala Ser Thr Ile Phe Gln Arg Asn Ser Gln Thr Asp Val Val Glu Ile 
65                  70                  75                  80


Arg Arg Ser Asn Cys Thr Asn His Val Ser Thr Glu Arg Phe Ser Gln 
                85                  90                  95


Gln Tyr Ser Ser Cys Ser Thr Ile Phe Leu Asp Asp Ser Thr Ala Ile 
            100                 105                 110


Gln His Tyr Leu Thr Met Thr Ile Ile Ser Val Thr Leu Glu Ile Pro 
        115                 120                 125


His His Ile Thr 
    130


<210>  6922
<211>  564
<212>  DNA
<213>  Homo sapiens

<400>  6922
agaggtcaat tagctgcttt cgggcggcct taggcgacag gagactcctg gacccagcac     60

ctgcccactg tgcctgtcca cctgtggcta cagcagctga gaccccagtg ggctaagatt    120

ggacaggggc caccagggac ccagcaagtc cttcagctct atttttgaaa catgaatcct    180

tcactcctcc tggctgcctt tttcctggga attgcctcag ctgctctaac acgtgaccac    240

agtctagacg cacaatggac caagtggaag gcaaagcaca agagattata tgacatgaat    300

gaagaaggat ggaggagagc agtgtgagag aacatgaaga tgactgagca gcacaatcag    360

gaatacagcc aagggaaaca cagcttcaca atggccatga acacctttgg agacatgacc    420

actgaagaat tcaggcaggt gatgaatggt tttcaatacc agaagcacag gaacgggaaa    480

cagttccagg aacgcctgct tcttgagatc cccacatctg tggactggag agagaaaggc    540

tacgtgactc ctgtgaagga tcag                                           564


<210>  6923
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  6923

Met Lys Met Thr Glu Gln His Asn Gln Glu Tyr Ser Gln Gly Lys His 
1               5                   10                  15


Ser Phe Thr Met Ala Met Asn Thr Phe Gly Asp Met Thr Thr Glu Glu 
            20                  25                  30


Phe Arg Gln Val Met Asn Gly Phe Gln Tyr Gln Lys His Arg Asn Gly 
        35                  40                  45


Lys Gln Phe Gln Glu Arg Leu Leu Leu Glu Ile Pro Thr Ser Val Asp 
    50                  55                  60


Trp Arg Glu Lys Gly Tyr Val Thr Pro Val Lys Asp 
65                  70                  75


<210>  6924
<211>  2064
<212>  DNA
<213>  Homo sapiens

<400>  6924
cagaaatcat gagtggagga tctcaagtcc acattttttg gggtgctcca gttgctccac     60

tgaaaatgac agtatcagaa gacacagctt ctttaatgtc tgttgctgac ccctggaaaa    120

aaattcagct tttatacagt caacattctt tatatctgaa ggatgaaaaa cagcacaaaa    180

atcttgaaaa ctatgaagtc ccagattcta ttggttctcc agatctttgt ggtcatttct    240

tagcaaactg tatgaataga catgttcatg tgaaagatga ctttgtacgt tctgtttctg    300

aaacacagaa tatagaatcc cagaagattc actcctctag actgagtggc ataactagct    360

ctaatatgca aatatgtgga tttaaaagca cagttccgca tttaaccgaa gaagaaaagt    420

atcaaagctt ctcagtgaaa ataaaattag agatgaacag cctaaacatc agccagatat    480

atgtggtcag aactttaaca caaatttgtt tcagttgggc cataaatgtg cagctgtgtt    540

ggatttggtt tgtagtactg aaaaaattaa tatagggcct gaagtggtac aaagagagtg    600

tgtgccaaca gaatatcatg aaatacaaaa ccagcgtttg ggattatttt cctcgaactc    660

agtagataag tcaaggtctg aagcagcagt taagaaggtc tcagacctta aaatatcaac    720

tgataaagaa tttctcagta taattacctc cagccaggtt gcttttttta gctcaaaaga    780

aagataaaag gcggagtcct gtaaataaag ggaatgtaaa catggagact gaaccaaagg    840

caagttacgg ggagataaga atacctgaag agaattcgat tcagcttgat ggttttacag    900

aagcatatga aagtggacaa aaccaagcat attcccttga actttttagt cctgtttgtc    960

ctaaaacaga aaatagccgc attcacataa actctgataa aggtcttgaa gaacatacag   1020

gatctcaaga acttttcagt tctgaagatg aactgccacc aaatgagata cgtattgagt   1080

tgtgtagctc aggaatactg tgttcccaac taaatacctt ccacaaaagt gctattaaaa   1140

gaagctgtac ctctgaagat aaagtggccc agtctgaagc tctatctaga gtccttcaag   1200

tagctaagaa aatgaagttg atttctaatg gaggagattc tgctgtagaa atggatcgga   1260

gaaatgtgtc tgaatttaag agtattaaaa aaatcattaa taaaaaactg tgattctaaa   1320

agccagaagt ataattgttt agtcatggtg ctatctccat gccatgtgaa ggaaataaac   1380

ataaaattcg gaccaaattc tggctctaaa gtgcctttag caacagttac agtaagtgat   1440

caatcagaaa ctaagaagaa ggtttttctg tggaggactg cagcattttg ggcatttaca   1500

gtgtttcttg gagatataat tttactcacg gatgttgtta ttcatgagga ccaatggatt   1560

ggtgagacag tactacaatc aacatttagc agtcagttat taaatcttgg gagttattca   1620

tctattcagc ctgaagaatt ctggagtgca gtggcgtgat cttggctcac tgcaacctct   1680

gcctcctggg ttctagcaat tctcctgctt cagcctccca agtagctggg actacagctc   1740

tatcttgttc atgaaaaacg aagcccagag aagttatgta caagttcaca gagctcatta   1800

ttgacaaaac cagaatttga atacaactct tctgattcca gatttgctgg aaatactgtg   1860

aaagaagaat tcagtctgat tccagtgtag ttagtgacgt tgtacttcaa gacttactgg   1920

catatgtgtc ctcaaaacat tcctacctca gagatcttcc tccgagacag cctcagaggg   1980

tgaacagtat agactttgta gaattggagc accttcaacc tgatgtgtta gtccacgcag   2040

tactaagagt tgttgatttc ctat                                          2064


<210>  6925
<211>  131
<212>  PRT
<213>  Homo sapiens

<400>  6925

Met Cys Leu Asn Leu Arg Val Leu Lys Lys Ser Leu Ile Lys Asn Cys 
1               5                   10                  15


Asp Ser Lys Ser Gln Lys Tyr Asn Cys Leu Val Met Val Leu Ser Pro 
            20                  25                  30


Cys His Val Lys Glu Ile Asn Ile Lys Phe Gly Pro Asn Ser Gly Ser 
        35                  40                  45


Lys Val Pro Leu Ala Thr Val Thr Val Ser Asp Gln Ser Glu Thr Lys 
    50                  55                  60


Lys Lys Val Phe Leu Trp Arg Thr Ala Ala Phe Trp Ala Phe Thr Val 
65                  70                  75                  80


Phe Leu Gly Asp Ile Ile Leu Leu Thr Asp Val Val Ile His Glu Asp 
                85                  90                  95


Gln Trp Ile Gly Glu Thr Val Leu Gln Ser Thr Phe Ser Ser Gln Leu 
            100                 105                 110


Leu Asn Leu Gly Ser Tyr Ser Ser Ile Gln Pro Glu Glu Phe Trp Ser 
        115                 120                 125


Ala Val Ala 
    130


<210>  6926
<211>  1780
<212>  DNA
<213>  Homo sapiens

<400>  6926
gggtcatgac gcagcgagtt tcagtcgtga cttttctggg ggcatcgcgg cgtccccttt     60

ttttgccttt aaagtaaaac gtcgccccga cgcacccccc gcgtatttcg gggggcggag    120

gcggcgggcc acggcgcgaa gaggggcggt gctgacgccg gccggtcacg tgggcgtgtt    180

gtgggggggg aggggcgccg ccgcgcggtc ggttccgggc ggttgggagc gcgcgagcta    240

gcgagcgaga ggcagccgcg cccgccgccg cccctgctct gtatgccgct ctctcccggc    300

gcggccgccg ccgatcacag cagcaggagc cgccgccgcc gcggttgatg tggttgggcc    360

ggggctgagg aggccgccaa gatgccgcag tcaaagtccc ggaagatcgc gatcctgggc    420

taccggtctg tggggaaatc ctcattgacg attcaatttg ttgaaggcca atttgtggac    480

tcctacgatc caaccataga aaacactttt acaaagttga tcacagtaaa tggacaagaa    540

tatcatcttt aacttgtaga cacagccggg caagatgaat attctatctt tcctcagaca    600

tactccatag atattaatgg ctatattctt gtgtattctg ttacatcaat caaaagtttt    660

gaagtgatta aagttatcca tggcaaattg ttggatatgg tggggaaagt acaaatacct    720

attatgttgg ttggaaataa gaaagacctg catatggaaa gggtgatcag ttatgaagaa    780

gggaaagctt tggcagaatc ttggaatgca gcttttttgg aatcttctgc taaagaaaat    840

cagactgctg ttgatgtttt tcgaaggatg attttggagg cagaaaaaat ggacgggggc    900

agcttcacaa ggcaagtctt catgctcggt gatgtgattc tgctgcaaag cccgaggaca    960

ctgggaatat attctagctg aagaagcaaa ctgcccgttc tccttgaaga taaactatgc   1020

ttcttttttc ttctgttaac ctgaaagata tcatttgggt cagagctccc ctcccttcag   1080

attatgttaa ctctgagtct gtccaaatga gttcacttcc attttcaaat tttaagcaat   1140

catattttca atttatatat tgtgtttctt aatattatga ccaagaattt tatcggcatt   1200

aatttttcag tgtagtttgt tgtttaaaat aatgtaatca tcaaaatgat gcatattgtt   1260

acactactat taactaggct tcaatatatc agtgtttatt tcattgtgtt aaatgtatac   1320

ttgtaaataa aatagctgca aacctcaaaa aaacaaaaaa aaacaaaaaa aagagtaaac   1380

caatttggtt actcatttta ccaatttggt tttgattttg caagtggtta caactcatga   1440

gaggattctt atttctgatc aatatattgt gtttttggaa aggacttctg ggaaataatt   1500

atgatgaagc cctcgagcaa ttgcaacaaa accaaaaatt gaaaagtggg acctaataat   1560

acttttttaa aatttatttt ttagagacag gatctcactc tgttacccag gctggagtgc   1620

agtggcctga tcatagctca ctgcagcctc aatctcccag gctcaagaga ttcttctacc   1680

tcagcctcct gaatagctgg gactacaggt gcatgccccc atgcccagct aatttttgta   1740

ttttttgtag agaccaggtt ttgtcatgtt gcccaagctg                         1780


<210>  6927
<211>  94
<212>  PRT
<213>  Homo sapiens

<400>  6927

Met Val Gly Lys Val Gln Ile Pro Ile Met Leu Val Gly Asn Lys Lys 
1               5                   10                  15


Asp Leu His Met Glu Arg Val Ile Ser Tyr Glu Glu Gly Lys Ala Leu 
            20                  25                  30


Ala Glu Ser Trp Asn Ala Ala Phe Leu Glu Ser Ser Ala Lys Glu Asn 
        35                  40                  45


Gln Thr Ala Val Asp Val Phe Arg Arg Met Ile Leu Glu Ala Glu Lys 
    50                  55                  60


Met Asp Gly Gly Ser Phe Thr Arg Gln Val Phe Met Leu Gly Asp Val 
65                  70                  75                  80


Ile Leu Leu Gln Ser Pro Arg Thr Leu Gly Ile Tyr Ser Ser 
                85                  90


<210>  6928
<211>  1448
<212>  DNA
<213>  Homo sapiens

<400>  6928
gggtcatgac gcagcgagtt tcagtcgtga cttttctggg ggcatcgcgg cgtccccttt     60

ttttgccttt aaagtaaaac gtcgccccga cgcacccccc gcgtatttcg gggggcggag    120

gcggcgggcc acggcgcgaa gaggggcggt gctgacgccg gccggtcacg tgggcgtgtt    180

gtgggggggg aggggcgccg ccgcgcggtc ggttccgggc ggttgggagc gcgcgagcta    240

gcgagcgaga ggcagccgcg cccgccgccg cccctgctct gtatgccgct ctctcccggc    300

gcggccgccg ccgatcacag cagcaggagc cgccgccgcc gcggttgatg tggttgggcc    360

ggggctgagg aggccgccaa gatgccgcag tcaaagtccc ggaagatcgc gatcctgggc    420

taccggtctg tggggaaatc ctcattgacg attcaatttg ttgaaggcca atttgtggac    480

tcctacgatc caaccataga aaacactttt acaaagttga tcacagtaaa tggacaagaa    540

tatcatcttt aacttgtaga cacagccggg caagatgaat attctatctt tcctcagaca    600

tactccatag atattaatgg ctatattctt gtgtattctg ttacatcaat caaaagtttt    660

gaagtgatta aagttatcca tggcaaattg ttggatatgg tggggaaagt acaaatacct    720

attatgttgg ttggaaataa gaaagacctg catatggaaa gggtgatcag ttatgaagaa    780

gggaaagctt tggcagaatc ttggaatgca gcttttttgg aatcttctgc taaagaaaat    840

cagactgctg ttgatgtttt tcgaaggatg attttggagg cagaaaaaat ggacgggggc    900

agcttcacaa gattccagtg tagttagtga cgttgtactt caagacttac tggcatatgt    960

gtcctcaaaa cattcctacc tcagagatct tcctccgaga cagcctcaga gggtgaacag   1020

tatagacttt gtagaattgg agcaccttca acctgatgtg ttagtccacg cagtactaag   1080

agttgttgat ttcctatact gacagaggca gtatacagtt atagaggaca gaagcagaaa   1140

aaagttatgt taacagtgga acaggcccaa gatcaacatt atgcgcttgt attatggggt   1200

cctggagcag cctggtaccc tcaacttcaa aggaaaaaag gttatatttg ggaatttaaa   1260

tatctttttg ttcagcgcaa ttacacacta gaaaacctag aattgcatac aacgccttgg   1320

tcatcctgtg agtgcttgtt tgatgatgat ataagggcaa ttacatttaa agcaaaattt   1380

caaaaaagtg caccctcctt tgtgaagata tcagacttag caacccacct agaggataag   1440

tgttcagg                                                            1448


<210>  6929
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  6929

Met Leu Thr Val Glu Gln Ala Gln Asp Gln His Tyr Ala Leu Val Leu 
1               5                   10                  15


Trp Gly Pro Gly Ala Ala Trp Tyr Pro Gln Leu Gln Arg Lys Lys Gly 
            20                  25                  30


Tyr Ile Trp Glu Phe Lys Tyr Leu Phe Val Gln Arg Asn Tyr Thr Leu 
        35                  40                  45


Glu Asn Leu Glu Leu His Thr Thr Pro Trp Ser Ser Cys Glu Cys Leu 
    50                  55                  60


Phe Asp Asp Asp Ile Arg Ala Ile Thr Phe Lys Ala Lys Phe Gln Lys 
65                  70                  75                  80


Ser Ala Pro Ser Phe Val Lys Ile Ser Asp Leu Ala Thr His Leu Glu 
                85                  90                  95


Asp Lys Cys 



<210>  6930
<211>  890
<212>  DNA
<213>  Homo sapiens

<400>  6930
ttttttttgt ttttttttgt ttttttgagg tttgcagcta ttttatttac aagtatacat     60

ttaacacaat gaaataaaca ctgatatatt gaagcctagt taatagtagt gtaacaatat    120

gcatcatttt gatgattaca ttattttaaa caacaaacta cactgaaaaa ttaatgccga    180

taaaattctt ggtcataata ttaagaaaca caatatataa attgaaaata tgattgctta    240

aaatttgaaa atggaagtga actcatttgg acagactcag agttaacata atctgaaggg    300

aggggagctc tgacccaaat gatatctttc aggttaacag aagaaaaaag aagcatagtt    360

tatcttcaag gagaacgggc agtttgcttc ttcagctaga atatattccc agtgtcctcg    420

ggctttgcag cagaatcaca tcaccgagca tgaagacttg ccttgtgaag ctgcccccgt    480

ccattttttc tgcctccaaa atcatccttc gaaaaacatc aacagcagtc tgattttctt    540

tagcagaaga ttccaaaaaa gctgcattcc aagattctgc caaagctttc ccttcttcat    600

aactgatcac cctttccata tgcaggtctt tcttatttcc aaccaacata ataggtattt    660

gtactttccc caccatatcc aacaatttgc catggataac tttaatcact tcaaaacttt    720

tgattgatgt aacagaatac acaagaatat agccattaat atctatggag tatgtctgag    780

gaaagataga atattcatcc cacagaccgg tagcccagga tcgcgatctt ccgggacttt    840

gactgcggca tcttggcggc ctcctcagcc ccggcccaac cacatcaacc               890


<210>  6931
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  6931

Met Gln Val Phe Leu Ile Ser Asn Gln His Asn Arg Tyr Leu Tyr Phe 
1               5                   10                  15


Pro His His Ile Gln Gln Phe Ala Met Asp Asn Phe Asn His Phe Lys 
            20                  25                  30


Thr Phe Asp 
        35


<210>  6932
<211>  1664
<212>  DNA
<213>  Homo sapiens

<400>  6932
aaggttatat ttgggaattt aaatatcttt ttgttcagcg caattacaca ctagaaaacc     60

tagaattgca tacaacgcct tggtcatcct gtgagtgctt gtttgatgat gatataaggg    120

caattacatt taaagcaaaa tttcaaaaaa gtgcaccctc ctttgtgaag atatcagact    180

tagcaaccca cctagaggat aagtgttcag gagtggttct aattaaagcc cagatttcag    240

agctggcatt tcctcttaca gcagctcaga agatatctct aaatgctcac agttctctga    300

agagtatttt ttcttctctt cccaacatca tatatactgg ctgtgcaaaa tgtggattgg    360

aactagaaac agatgagaac aggatctaca aacaatgttt tagctgcttg ccatttacta    420

tgaagaaaat atattatagg ccagcgttaa tgactgccgt tgatggaaga cataatgttt    480

acatccatgt agaatcaaag ctgatagaga agattcttct caacatttct gcagactgcc    540

tcaacagagt gatagatgga gttttgctct tgttgcctag actggagtgc tgtggcgcga    600

tctcagttca ccataacctc tgcctcctgg attcaagcaa gtctcctgcc tcagtttccc    660

aagtagctgg gattacagtt ccttcctcag agatcaccta tgggatggtt gtggcagacc    720

tgttccactc cttgttggca gtcagcgcag aaccttgtgt attgaagatt cagagccttt    780

ttgtgttaga tgaaaacagc tatccattac aacaagattt ctccctcctg gatttttatc    840

ctgacatggt aaagcatgga gccaatgccc gtctctgagg ccagaggaag aaattgcagg    900

catttcaagg aagaagtact gaaatgattt gtcttttgaa ataaatgaat gacagggctt    960

ttgctttgga ttttttatga aatatatttt acaaagagaa ttgcactaga tatataaatt   1020

aaaacttttt tctaagaaaa tcctgtgagg tttaaaaaga ttgtttttgt cttttggttt   1080

cttcctttct tctggagaaa tgatctacca gtcaaggcaa tatgtagcag atccctggga   1140

attaaaggtt tgcccatttg ttcactgtat ttagtccctg ctacattcca ggcatcgtac   1200

taagtatggg gaaccacaga gaagacactc cttcagaaac tgctgcagtg ctttcgctta   1260

tccctaccta aaaaaccgtc aatgtgaaat catttccttg attataacta taatgataat   1320

ggattagttt atataaacct atgtttagac aagttcaaga caagcgtgtc tttctataaa   1380

aagtattgaa agtgaaggaa atgagatcat gtttcaattt attaaagcag ggaagagcgt   1440

tctgtggtta gttcgtgtct aggatttgag tgccttactg aatgtattta ccagcaaaca   1500

tgtagcaatc tgttctctca ttgtgattgt ggaagaagct catgtaaaat gatagtcatt   1560

aatgaggaag tatggcgtgg tacttattct gtaagttcag agtatgctga gtgttaatag   1620

attgtcatat tgcctgaaaa taaattcatg atgacatgaa caag                    1664


<210>  6933
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  6933

Met Lys Lys Ile Tyr Tyr Arg Pro Ala Leu Met Thr Ala Val Asp Gly 
1               5                   10                  15


Arg His Asn Val Tyr Ile His Val Glu Ser Lys Leu Ile Glu Lys Ile 
            20                  25                  30


Leu Leu Asn Ile Ser Ala Asp Cys Leu Asn Arg Val Ile Asp Gly Val 
        35                  40                  45


Leu Leu Leu Leu Pro Arg Leu Glu Cys Cys Gly Ala Ile Ser Val His 
    50                  55                  60


His Asn Leu Cys Leu Leu Asp Ser Ser Lys Ser Pro Ala Ser Val Ser 
65                  70                  75                  80


Gln Val Ala Gly Ile Thr Val Pro Ser Ser Glu Ile Thr Tyr Gly Met 
                85                  90                  95


Val Val Ala Asp Leu Phe His Ser Leu Leu Ala Val Ser Ala Glu Pro 
            100                 105                 110


Cys Val Leu Lys Ile Gln Ser Leu Phe Val Leu Asp Glu Asn Ser Tyr 
        115                 120                 125


Pro Leu Gln Gln Asp Phe Ser Leu Leu Asp Phe Tyr Pro Asp Met Val 
    130                 135                 140


Lys His Gly Ala Asn Ala Arg Leu 
145                 150


<210>  6934
<211>  1025
<212>  DNA
<213>  Homo sapiens

<400>  6934
ttctcaacat ttctgcagac tgcctcaaca gagtgatagt tccttcctca gagatcacct     60

atgggatggt tgtggcagac ctgttccact ccttgttggc agtcagcgca gaaccttgtg    120

tattgaagat tcagagcctt tttgtgttag atgaaaacag ctatccatta caacaagatt    180

tctccctcct ggatttttat cctgacatgg taaagcatgg agccaatgcc cgtctctgag    240

gccagaggaa gaaattgcag gcatttcaag gaagaagtac tgaaatgatt tgtcttttga    300

aataaatgaa tgacagggct tttgctttgg attttttatg aaatatattt tacaaagaga    360

attgcactag atatataaat taaaactttt ttctaagaaa atcctgtgag gtttaaaaag    420

attgtttttg tcttttggtt tcttcctttc ttctggagaa atgatctacc agtcaaggca    480

atatgtagca gatccctggg aattaaaggt ttgcccattt gttcactgta tttagtccct    540

gctacattcc aggcatcgta ctaagtatgg ggaaccacag agaagacact ccttcagaaa    600

ctgctgcagt gctttcgctt atccctacct aaaaaaccgt caatgtgaaa tcatttcctt    660

gattataact ataatgataa tggattagtt tatataaacc tatgtttaga caagttcaag    720

acaagcgtgt ctttctataa aaagtattga aagtgaagga aatgagatca tgtttcaatt    780

tattaaagca gggaagagcg ttctgtggtt agttcgtgtc taggatttga gtgccttact    840

gaatgtattt accagcaaac atgtagcaat ctgttctctc attgtgattg tggaagaagc    900

tcatgtaaaa tgatagtcat taatgaggaa gtatggcgtg gtacttattc tgtaagttca    960

gagtatgctg agtgttaata gattgtcata ttgcctgaaa ataaattcat gatgacatga   1020

acaag                                                               1025


<210>  6935
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  6935

Met Val Val Ala Asp Leu Phe His Ser Leu Leu Ala Val Ser Ala Glu 
1               5                   10                  15


Pro Cys Val Leu Lys Ile Gln Ser Leu Phe Val Leu Asp Glu Asn Ser 
            20                  25                  30


Tyr Pro Leu Gln Gln Asp Phe Ser Leu Leu Asp Phe Tyr Pro Asp Met 
        35                  40                  45


Val Lys His Gly Ala Asn Ala Arg Leu 
    50                  55


<210>  6936
<211>  536
<212>  DNA
<213>  Homo sapiens

<400>  6936
tatcttcagt gaaagcacta tcattgggag tacttcattg aagtcagctt gaacaacggc     60

aaaacattca agagcaatgt cagcatcacc agcaccacat gtactcgtgg aacaaatacc    120

acggagcagc acctagcaca gaggaaggcc ccctgccctg ggcatctgtg ggaaaccagg    180

gcccaagtct gcggtgagct ggtgcagaaa ctctgagctg aggagctaac attacaccca    240

tctgcaactg agagaacctg ccaggctcca gcaaaaccaa acaggacatt ctccccagga    300

gacaccgtcc tcatccaggg gaaccaggat tctcatggaa aatcatttcc tactgaagac    360

gaggtcagag gaaaaactcc caggtatccc aaagagaggc agcagataca agaaacaagg    420

agattcaaag cccagagagt aaagagaata gagtgatcta aaaggaacat tgaaataagg    480

gtgtataaaa tgttcaaaaa aagataaagg aataaaacta tatgacaaga acagct        536


<210>  6937
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  6937

Met Tyr Ser Trp Asn Lys Tyr His Gly Ala Ala Pro Ser Thr Glu Glu 
1               5                   10                  15


Gly Pro Leu Pro Trp Ala Ser Val Gly Asn Gln Gly Pro Ser Leu Arg 
            20                  25                  30


<210>  6938
<211>  654
<212>  DNA
<213>  Homo sapiens

<400>  6938
gccagcaagt ctagcagaca tgcaagccct gcctcagctt ctctcccaac actcagcttt     60

tctcccaata caggaacttt tggaggtcac ttctggggcc tttgctgagc aggccactcc    120

ttgcttctcc tgcagatgac aaggtttcca gcatgattat tgctatgact gatggaacaa    180

tgatgaaaca tccatctttg gacactctca aagaaggagt acttcattga agtcagcttg    240

aacaacggca aaacattcaa gagcaatgtc agcatcacca gcaccacatg tactcgtgga    300

acaaatacca cggagcagca cctagcacag aggaaggccc cctgccctgg gcatctgtgg    360

gaaaccaggg cccaagtctg cggtgagctg gtgcagaaac tctgagctga ggagctaaca    420

ttacacccat ctgcaactga gagaacctgc caggctccag caaaaccaaa caggacattc    480

tccccaggag acaccgtcct catccagggg aaccaggatt ctcatggaaa atcatttcct    540

actgaagacg aggtcagagg aaaaactccc aggtatccca aagagaggca gcagatacaa    600

gaaacaagga gattcaaagc ccagagagta aagagaatag agtgatctaa aagg          654


<210>  6939
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  6939

Met Tyr Ser Trp Asn Lys Tyr His Gly Ala Ala Pro Ser Thr Glu Glu 
1               5                   10                  15


Gly Pro Leu Pro Trp Ala Ser Val Gly Asn Gln Gly Pro Ser Leu Arg 
            20                  25                  30


<210>  6940
<211>  480
<212>  DNA
<213>  Homo sapiens

<400>  6940
tgcaagccct gcctcagctt ctctcccaac actcagcttt tctcccaata caggaacttt     60

tggaggtcac ttctggggcc tttgctgagc aggccactcc ttgcttctcc tgcagatgac    120

aaggtttcca gcatgattat tgctatgact gatggaacaa tgatgaaaca tccatctttg    180

gacactctca aagaaaatcc taccatgtgg ttattcatgg aaatggcttt cagaatctaa    240

agaaacggga tgaagttatt tgcagattta tcttcagtga aagcactatc attgggagta    300

cttcattgaa gtcagcttga acaacggcaa aacattcaag agcaatgtca gcatcaccag    360

caccacatgt ggcaatctgg atatcttccg tgacctctct cacccaagct gctgccaggt    420

gccatggatg tggtgtcagc acaggggcca gactcgtgga acaaatacca cggagcagca    480


<210>  6941
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  6941

Met Ser Ala Ser Pro Ala Pro His Val Ala Ile Trp Ile Ser Ser Val 
1               5                   10                  15


Thr Ser Leu Thr Gln Ala Ala Ala Arg Cys His Gly Cys Gly Val Ser 
            20                  25                  30


Thr Gly Ala Arg Leu Val Glu Gln Ile Pro Arg Ser 
        35                  40


<210>  6942
<211>  9708
<212>  DNA
<213>  Homo sapiens

<400>  6942
aaacaaccag tgctgtgtag ccaaagccaa accaatgcaa aggcactaat gggaagaggg     60

gcttctccat tcttctcttc tcagtccaga aaggagacta ccccaggcct gcatctcctg    120

aaggcccgtg gggagcacaa tggagcgcaa gccgcgggac acagctgcca gtctgctccg    180

gcgccgcttt gtgcgcgcag ccgctggccc ctctactccc gggtctgccc cccgggacac    240

ccctctgcct cgcccaagtc atgcagccct acctgcctct ccactgtgga cctttgggaa    300

ccgactcctc acctcggggg ctcgggcctt gactgtgctg ggagccggta ggcgtcctcc    360

gcgacccgcc cgcgcccctc gcgcccgccg gggccccggg ctccaaagtt gtggggaccg    420

gcgcgagttg gaaagtttgc ccgagggctg gtgcaggctt ggagctgggg gccgtgcgct    480

gccctgggaa tgtgacccgg ccagcgacca aaaccttgtg tgactgagct gaagagcagt    540

gcatccagat tctcctcaga agtgagactt tccaaaggac caatgactct gtttcctgcg    600

ccctttcatt ttttcctact ctgtagctat gtctcgatcc cgccatgcaa ggccttccag    660

attagtcagg aaggaagatg taaacaaaaa aaagaaaaac agccaactac gaaagacaac    720

caagggagcc aacaaaaatg tggcatcagt caagacttta agccctggaa aattaaagca    780

attaattcaa gaaagagatg ttaagaaaaa aacagaacct aaaccacccg tgccagtcag    840

aagccttctg acaagagctg gagcagcacg catgaatttg gataggactg aggttctttt    900

tcagaaccca gagtccttaa cctgcaatgg gtttacaatg gcgctacgaa gcacctctct    960

tagcaggcga ctctcccaac ccccactggt cgtagccaaa tccaaaaagg ttccactttc   1020

taagggttta gaaaagcaac atgattgtga ttataagata ctccctgctt tgggagtaaa   1080

gcactcagaa aatgattcgg ttccaatgca agacacccaa gtccttcctg atatagagac   1140

tctaattggt gtacaaaatc cctctttact taaaggtaag agccaagaga caactcagtt   1200

ttggtcccaa agagttgagg attccaagat caatatccct acccacagtg gccctgcagc   1260

tgagatcctt cctgggccac tggaagggac acgctgtggt gaaggactat tctctgaaga   1320

gacattgaat gataccagtg gttccccaaa aatgtttgct caggacacag tgtgtgctcc   1380

ttttccccaa agagcaaccc ccaaagttac ctctcaagga aaccccagca ttcagttaga   1440

agagttgggt tcacgagtag aatctcttaa gttatctgat tcttacctgg atcccattaa   1500

aagtgaacat gattgctacc ccacctccag tcttaataag gttatacctg acttgaacct   1560

tagaaactgc ttggctcttg gtgggtctac gtctcctacc tctgtaataa aattcctctt   1620

ggcaggctca aaacaagcga cccttggtgc taaaccagat catcaagagg ccttcgaagc   1680

tactgcaaat caacaggaag tttctgatac cacctctttc ctaggacagg cctttggtgc   1740

tatcccacat caatgggaac ttcctggtgc tgacccagtt catggtgagg ccctgggtga   1800

gaccccagat ctaccagaga ttcctggtgc tattccagtc caaggagagg tctttggtac   1860

tattttagac caacaagaaa ctcttggtat gagtgggagt gttgtcccag acttgcctgt   1920

cttccttcct gttcctccaa atccaattgc tacctttaat gctccttcca aatggcctga   1980

gccccaaagc actgtctcat atggacttgc agtccagggt gctatacaga ttttgccttt   2040

gggctcagga cacactcctc aatcatcatc aaactcagag aaaaattcat tacctccagt   2100

aatggctata agcaatgtag aaaatgagaa gcaggttcat ataagcttcc tgccagctaa   2160

cactcagggg ttcccattag cccctgagag aggactcttc catgcttcac tgggtatagc   2220

ccaactctct caggctggtc ctagcaaatc agacagaggg agctcccagg tcagtgtaac   2280

cagcacagtt catgttgtca acaccacagt ggtgactatg ccagtgccaa tggtcagtac   2340

ctcctcttct tcctatacca ctttgctacc gactttggaa aagaagaaaa gaaagcgatg   2400

tggggtctgt gaaccctgcc agcagaagac caactgtggt gaatgcactt actgcaagaa   2460

cagaaagaac agccatcaga tctgtaagaa aagaaaatgt gaggagctga aaaagaaacc   2520

atctgttgtt gtgcctctgg aggttataaa ggaaaacaag aggccccaga gggaaaagaa   2580

gcccaaagtt ttaaagattt tgacaacaaa ccagtaaatg gccccaagtc agaatccatg   2640

gactacagta gatgtggtca tggggaagaa caaaaattgg aattgaaccc acatactgtt   2700

gaaaatgtaa ctaaaaatga agacagcatg acaggcatcg aggtggagaa gtggacacaa   2760

aacaagaaat cacagttaac tgatcacgtg aaaggagatt ttagtgctaa tgtcccagaa   2820

gctgaaaaat cgaaaaactc tgaagttgac aagaaacgaa ccaaatctcc aaaattgttt   2880

gtacaaaccg taagaaatgg cattaaacat gtacactgtt taccagctga aacaaatgtt   2940

tcatttaaaa aattcaatat tgaagaattc ggcaagacat tggaaaacaa ttcttataaa   3000

ttcctaaaag acactgcaaa ccataaaaac gctatgagct ctgttgctac tgatatgagt   3060

tgtgatcatc tcaaggggag aagtaacgtt ttagtattcc agcagcctgg ctttaactgc   3120

agttccattc cacattcttc acactccatc ataaatcatc atgctagtat acacaatgaa   3180

ggtgatcaac caaaaactcc tgagaatata ccaagtaaag aaccaaaaga tggatctccc   3240

gttcaaccaa gtctcttatc gttaatgaaa gataggagat taacattgga gcaagtggta   3300

gccatagagg ccctgactca actctcagaa gccccatcag agaattcctc cccatcaaag   3360

tcagagaagg atgaggaatc agagcagaga acagccagtt tgcttaatag ctgcaaagct   3420

atcctctaca ctgtaagaaa agacctccaa gacccaaact tacagggaga gccaccaaaa   3480

cttaatcact gtccatcttt ggaaaaacaa agttcatgca acacggtggt tttcaatggg   3540

caaactacta ccctttccaa ctcacatatc aactcagcta ctaaccaagc atccacaaag   3600

tcacatgaat attcaaaagt cacaaattca ttatctcttt ttataccaaa atcaaattca   3660

tccaagattg acaccaataa aagtattgct caagggataa ttactcttga caattgttcc   3720

aatgatttgc atcagttgcc accaagaaat aatgaagtgg agtattgcaa ccagttactg   3780

gacagcagca aaaaattgga ctcagatgat ctatcatgtc aggatgcaac ccatacccaa   3840

attgaggaag atgttgcaac acagttgaca caacttgctt cgataattaa gatcaattat   3900

ataaaaccag aggacaaaaa agttgaaagt acaccaacaa gccttgtcac atgtaatgta   3960

cagcaaaaat acaatcagga gaagggcaca atacaacaga aaccaccttc aagtgtacac   4020

aataatcatg gttcatcatt aacaaaacaa aagaacccaa cccagaaaaa gacaaaatcc   4080

accccatcaa gagatcggcg gaaaaagaag cccacagttg taagttatca agaaaatgat   4140

cggcagaagt gggaaaagtt gtcctatatg tatggcacaa tatgcgacat ttggatagca   4200

tcgaaatttc aaaattttgg gcaattttgt ccacatgatt ttcctactgt atttgggaaa   4260

atttcttcct cgaccaaaat atggaaacca ctggctcaaa cgaggtccat tatgcaaccc   4320

aaaacagtat ttccaccact cactcagata aaattacaga gatatcctga atcagcagag   4380

gaaaaggtga aggttgaacc attggattca ctcagcttat ttcatcttaa aacggaatcc   4440

aacgggaagg cattcactga taaagcttat aattctcagg tacagttaac ggtgaatgcc   4500

aatcagaaag cccatccttt gacccagccc tcctctccac ctaaccagtg tgctaacgtg   4560

atggcaggcg atgaccaaat acggtttcag caggttgtta aggagcaact catgcatcag   4620

agactgccaa cattgcctgg tatctctcat gaaacaccct taccggagtc agcactaact   4680

ctcaggaatg taaatgtagt gtgttcaggt ggaattacag tggtttctac caaaagtgaa   4740

gaggaagtct gttcatccag ttttggaaca tcagaatttt ccacagtgga cagtgcacag   4800

aaaaatttta atgattatgc catgaacttc tttactaacc ctacaaaaaa cctagtgtct   4860

ataactaaag attctgaact gcccacctgc agctgtcttg atcgagttat acaaaaagac   4920

aaaggcccat attatacaca ccttggggca ggaccaagtg ttgctgctgt cagggaaatc   4980

atggagaata ggtatggtca aaaaggaaac gcaataagga tagaaatagt agtgtacacc   5040

ggtaaagaag ggaaaagctc tcatgggtgt ccaattgcta agtgggtttt aagaagaagc   5100

agtgatgaag aaaaagttct ttgtttggtc cggcagcgta caggccacca ctgtccaact   5160

gctgtgatgg tggtgctcat catggtgtgg gatggcatcc ctcttccaat ggccgaccgg   5220

ctatacacag agctcacaga gaatctaaag tcatacaatg ggcaccctac cgacagaaga   5280

tgcaccctca atgaaaatcg tacctgtaca tgtcaaggaa ttgatccaga gacttgtgga   5340

gcttcattct cttttggctg ttcatggagt atgtacttta atggctgtaa gtttggtaga   5400

agcccaagcc ccagaagatt tagaattgat ccaagctctc ccttacatga aaaaaacctt   5460

gaagataact tacagagttt ggctacacga ttagctccaa tttataagca gtatgctcca   5520

gtagcttacc aaaatcaggt ggaatatgaa aatgttgccc gagaatgtcg gcttggcagc   5580

aaggaaggtc gtcccttctc tggggtcact gcttgcctgg acttctgtgc tcatccccac   5640

agggacattc acaacatgaa taatggaagc actgtggttt gtaccttaac tcgagaagat   5700

aaccgctctt tgggtgttat tcctcaagat gagcagctcc atgtgctacc tctttataag   5760

ctttcagaca cagatgagtt tggctccaag gaaggaatgg aagccaagat caaatctggg   5820

gccatcgagg tcctggcacc ccgccgcaaa aaaagaacgt gtttcactca gcctgttccc   5880

cgttctggaa agaagagggc tgcgatgatg acagaggttc ttgcacataa gataagggca   5940

gtggaaaaga aacctattcc ccgaatcaag cggaagaata actcaacaac aacaaacaac   6000

agtaagcctt cgtcactgcc aaccttaggg agtaacactg agaccgtgca acctgaagta   6060

aaaagtgaaa ccgaacccca ttttatctta aaaagttcag acaacactaa aacttattcg   6120

ctgatgccat ccgctcctca cccagtgaaa gaggcatctc caggcttctc ctggtccccg   6180

aagactgctt cagccacacc agctccactg aagaatgacg caacagcctc atgcgggttt   6240

tcagaaagaa gcagcactcc ccactgtacg atgccttcgg gaagactcag tggtgccaat   6300

gcagctgctg ctgatggccc tggcatttca cagcttggcg aagtggctcc tctccccacc   6360

ctgtctgctc ctgtgatgga gcccctcatt aattctgagc cttccactgg tgtgactgag   6420

ccgctaacgc ctcatcagcc aaaccaccag ccctccttcc tcacctctcc tcaagacctt   6480

gcctcttctc caatggaaga agatgagcag cattctgaag cagatgagcc tccatcagac   6540

gaacccctat ctgatgaccc cctgtcacct gctgaggaga aattgcccca cattgatgag   6600

tattggtcag acagtgagca catctttttg gatgcaaata ttggtggggt ggccatcgca   6660

cctgctcacg gctcggtttt gattgagtgt gcccggcgag agctgcacgc taccactcct   6720

gttgagcacc ccaaccgtaa tcatccaacc cgcctctccc ttgtctttta ccagcacaaa   6780

aacctaaata agccccaaca tggttttgaa ctaaacaaga ttaagtttga ggctaaagaa   6840

gctaagaata agaaaatgaa ggcctcagag caaaaagacc aggcagctaa tgaaggtcca   6900

gaacagtcct ctgaagtaaa tgaattgaac caaattcctt ctcataaagc attaacatta   6960

acccatgaca atgttgtcac cgtgtcccct tatgctctca cacacgttgc ggggccctat   7020

aaccattggg tctgaaggct tttctccccc tcttaatgcc tttgctagtg cagtgtattt   7080

tttcaaggtg ctgttaaaag aaagtcatgt tgtcgtttac tatcttcatc tcacccattt   7140

caagtctgag gtaaaaaaat aataatgata acaaaacggg gtgggtattc ttaactgtga   7200

ctatattttg acaattggta gaaggtgcac attttaagca aaaataaaag ttttatagtt   7260

ttaaatacat aaagaaatgt ttcagttagg cattaacctt gatagaatca ctcagtttgg   7320

tgctttaaat taagtctgtt tactatgaaa caagagtcat ttttagagga ttttaacagg   7380

ttcatgttct atgatgtaaa atcaagacac acagtgttaa ctctacacag cttctggtgc   7440

ttaaccacat ccacacagtt aaaaataagc tgaattatta tttcatggtg ccattgttcc   7500

aacatcttcc aatcattgct agaaaattgg catattcctt tgaaataaac ttatgaaatg   7560

ttttctctct taaaatattt ctcctgtgta aaataaatca ttgttgttag taatggttgg   7620

aggctgttca taaattgtaa atatatattt taaaagcact ttctattttt aaaagtaact   7680

tgaaataata tagtataaga atcctattgt ctattgtttg tgcatatttg catacaagag   7740

aaatcattta tccttgctgt gtagagttcc atcttgttaa ctgcagtatg tattctaatc   7800

atgtatatgg tttgtgttct tttactgtgt cctctcacat tcaagtatta gcaacttgca   7860

gtatataaaa tagttagata atgagaagtt gttaattatc tctaaaattg gaattaggaa   7920

gcatatcacc aatactgatt aacattctct ttggaactag gtaagagtgg tctcttctta   7980

ttgaacaacc tcaatttagt ttcatcccac ctttctcagt ataatccatg agaggtgttt   8040

ccaaaaggag atgagggaac aggataggtt tcagaagagt caaatgcttc taatgtctca   8100

aggtgataaa atacaaaaac taagtagaca gatatttgta ctgaagtctg atacagaatt   8160

agaaaaaaaa aattcttgtt gaaatatttt gaaaacaaat tccctactat catcacatgc   8220

ctccccaacc ccaagtcaaa aacaagagga atggtactac aaacatggct ttgtccatta   8280

agagctaatt catttgttta tcttagcata ctagatttgg gaaaatgata actcatcttt   8340

tctgataatt gcctatgttc taggtaacag gaaaacaggc attaagttta ttttagtctt   8400

cccattttct tcctattact ttattgactc attttattgc aaaacaaaaa ggattaccca   8460

aacaacatgt ttcgaacaag gagaattttc aatgaaatac ttgattctgt taaaatgcag   8520

aggtgctata acattcaaag tgtcagattc cttgggagta tggaaaacct aatggtgctt   8580

ctcccttgga aatgccatag gaagcccaca accgctaaca cttacaattt tggtgcaaaa   8640

gcaaacagtt ccagcaggct ctctaaagaa aaactcattg taacttatta aaataatatc   8700

tggtgcaaag tatctgtttt gagcttttga ctaatccaag taaaggaata tgaagggatt   8760

gtaaaaaaca aaatgtccat tgatagacca tcgtgtacaa gtagatttct gcttgttgaa   8820

tatgtaaaat agggtaattc attgacttgt tttagtattt tgtgtgcctt agatttccgt   8880

tttaagacat gtatattttt gtgagcctaa ggtttcttat atacatataa gtatataaat   8940

aagtgattgt ttattgcttc agctgcttca acaagatatt tactagtatt agactatcag   9000

gaatacaccc ttgcgagatt atgttttaga ttttaggcct tagctcccac tagaaattat   9060

ttcttcacca gatttaatgg ataaagtttt atggctcttt atgcatccac tcatctactc   9120

attcttcgag tctacactta ttgaatgcct gcaaaatcta agtatcactt ttatttttct   9180

ttggatcacc acctatgaca tagtaaactt gaagaataaa aactaccctc agaaatattt   9240

ttaaaagaag tagcaaatta tcttcagtat aatccatggt aatgtatgca gtaattcaaa   9300

ttgatctctc tctcaatagg tttcttaaca atctaaactt gaaacatcaa tgttaatttt   9360

tggaactatt gggatttgtg acgcttgttg cagtttacca aaacaagtat ttgaaaatat   9420

atagtatcaa ctgaaatgtt tccattccgt tgttgtagtt aacatcatga atggacttct   9480

taagctgatt accccactgt gggaaccaaa ttggattcct actttgttgg actctctttc   9540

ctgattttaa caatttacca tcccattctc tgccctgtga ttttttttaa aagcttattc   9600

aatgttctgc agcattgtga ttgtatgctg gctacactgc ttttagaatg ctctttctca   9660

tgaagcaagg aaataaattt gtttgaaatg acattttctc tcataaaa                9708


<210>  6943
<211>  1465
<212>  PRT
<213>  Homo sapiens

<400>  6943

Met Asp Tyr Ser Arg Cys Gly His Gly Glu Glu Gln Lys Leu Glu Leu 
1               5                   10                  15


Asn Pro His Thr Val Glu Asn Val Thr Lys Asn Glu Asp Ser Met Thr 
            20                  25                  30


Gly Ile Glu Val Glu Lys Trp Thr Gln Asn Lys Lys Ser Gln Leu Thr 
        35                  40                  45


Asp His Val Lys Gly Asp Phe Ser Ala Asn Val Pro Glu Ala Glu Lys 
    50                  55                  60


Ser Lys Asn Ser Glu Val Asp Lys Lys Arg Thr Lys Ser Pro Lys Leu 
65                  70                  75                  80


Phe Val Gln Thr Val Arg Asn Gly Ile Lys His Val His Cys Leu Pro 
                85                  90                  95


Ala Glu Thr Asn Val Ser Phe Lys Lys Phe Asn Ile Glu Glu Phe Gly 
            100                 105                 110


Lys Thr Leu Glu Asn Asn Ser Tyr Lys Phe Leu Lys Asp Thr Ala Asn 
        115                 120                 125


His Lys Asn Ala Met Ser Ser Val Ala Thr Asp Met Ser Cys Asp His 
    130                 135                 140


Leu Lys Gly Arg Ser Asn Val Leu Val Phe Gln Gln Pro Gly Phe Asn 
145                 150                 155                 160


Cys Ser Ser Ile Pro His Ser Ser His Ser Ile Ile Asn His His Ala 
                165                 170                 175


Ser Ile His Asn Glu Gly Asp Gln Pro Lys Thr Pro Glu Asn Ile Pro 
            180                 185                 190


Ser Lys Glu Pro Lys Asp Gly Ser Pro Val Gln Pro Ser Leu Leu Ser 
        195                 200                 205


Leu Met Lys Asp Arg Arg Leu Thr Leu Glu Gln Val Val Ala Ile Glu 
    210                 215                 220


Ala Leu Thr Gln Leu Ser Glu Ala Pro Ser Glu Asn Ser Ser Pro Ser 
225                 230                 235                 240


Lys Ser Glu Lys Asp Glu Glu Ser Glu Gln Arg Thr Ala Ser Leu Leu 
                245                 250                 255


Asn Ser Cys Lys Ala Ile Leu Tyr Thr Val Arg Lys Asp Leu Gln Asp 
            260                 265                 270


Pro Asn Leu Gln Gly Glu Pro Pro Lys Leu Asn His Cys Pro Ser Leu 
        275                 280                 285


Glu Lys Gln Ser Ser Cys Asn Thr Val Val Phe Asn Gly Gln Thr Thr 
    290                 295                 300


Thr Leu Ser Asn Ser His Ile Asn Ser Ala Thr Asn Gln Ala Ser Thr 
305                 310                 315                 320


Lys Ser His Glu Tyr Ser Lys Val Thr Asn Ser Leu Ser Leu Phe Ile 
                325                 330                 335


Pro Lys Ser Asn Ser Ser Lys Ile Asp Thr Asn Lys Ser Ile Ala Gln 
            340                 345                 350


Gly Ile Ile Thr Leu Asp Asn Cys Ser Asn Asp Leu His Gln Leu Pro 
        355                 360                 365


Pro Arg Asn Asn Glu Val Glu Tyr Cys Asn Gln Leu Leu Asp Ser Ser 
    370                 375                 380


Lys Lys Leu Asp Ser Asp Asp Leu Ser Cys Gln Asp Ala Thr His Thr 
385                 390                 395                 400


Gln Ile Glu Glu Asp Val Ala Thr Gln Leu Thr Gln Leu Ala Ser Ile 
                405                 410                 415


Ile Lys Ile Asn Tyr Ile Lys Pro Glu Asp Lys Lys Val Glu Ser Thr 
            420                 425                 430


Pro Thr Ser Leu Val Thr Cys Asn Val Gln Gln Lys Tyr Asn Gln Glu 
        435                 440                 445


Lys Gly Thr Ile Gln Gln Lys Pro Pro Ser Ser Val His Asn Asn His 
    450                 455                 460


Gly Ser Ser Leu Thr Lys Gln Lys Asn Pro Thr Gln Lys Lys Thr Lys 
465                 470                 475                 480


Ser Thr Pro Ser Arg Asp Arg Arg Lys Lys Lys Pro Thr Val Val Ser 
                485                 490                 495


Tyr Gln Glu Asn Asp Arg Gln Lys Trp Glu Lys Leu Ser Tyr Met Tyr 
            500                 505                 510


Gly Thr Ile Cys Asp Ile Trp Ile Ala Ser Lys Phe Gln Asn Phe Gly 
        515                 520                 525


Gln Phe Cys Pro His Asp Phe Pro Thr Val Phe Gly Lys Ile Ser Ser 
    530                 535                 540


Ser Thr Lys Ile Trp Lys Pro Leu Ala Gln Thr Arg Ser Ile Met Gln 
545                 550                 555                 560


Pro Lys Thr Val Phe Pro Pro Leu Thr Gln Ile Lys Leu Gln Arg Tyr 
                565                 570                 575


Pro Glu Ser Ala Glu Glu Lys Val Lys Val Glu Pro Leu Asp Ser Leu 
            580                 585                 590


Ser Leu Phe His Leu Lys Thr Glu Ser Asn Gly Lys Ala Phe Thr Asp 
        595                 600                 605


Lys Ala Tyr Asn Ser Gln Val Gln Leu Thr Val Asn Ala Asn Gln Lys 
    610                 615                 620


Ala His Pro Leu Thr Gln Pro Ser Ser Pro Pro Asn Gln Cys Ala Asn 
625                 630                 635                 640


Val Met Ala Gly Asp Asp Gln Ile Arg Phe Gln Gln Val Val Lys Glu 
                645                 650                 655


Gln Leu Met His Gln Arg Leu Pro Thr Leu Pro Gly Ile Ser His Glu 
            660                 665                 670


Thr Pro Leu Pro Glu Ser Ala Leu Thr Leu Arg Asn Val Asn Val Val 
        675                 680                 685


Cys Ser Gly Gly Ile Thr Val Val Ser Thr Lys Ser Glu Glu Glu Val 
    690                 695                 700


Cys Ser Ser Ser Phe Gly Thr Ser Glu Phe Ser Thr Val Asp Ser Ala 
705                 710                 715                 720


Gln Lys Asn Phe Asn Asp Tyr Ala Met Asn Phe Phe Thr Asn Pro Thr 
                725                 730                 735


Lys Asn Leu Val Ser Ile Thr Lys Asp Ser Glu Leu Pro Thr Cys Ser 
            740                 745                 750


Cys Leu Asp Arg Val Ile Gln Lys Asp Lys Gly Pro Tyr Tyr Thr His 
        755                 760                 765


Leu Gly Ala Gly Pro Ser Val Ala Ala Val Arg Glu Ile Met Glu Asn 
    770                 775                 780


Arg Tyr Gly Gln Lys Gly Asn Ala Ile Arg Ile Glu Ile Val Val Tyr 
785                 790                 795                 800


Thr Gly Lys Glu Gly Lys Ser Ser His Gly Cys Pro Ile Ala Lys Trp 
                805                 810                 815


Val Leu Arg Arg Ser Ser Asp Glu Glu Lys Val Leu Cys Leu Val Arg 
            820                 825                 830


Gln Arg Thr Gly His His Cys Pro Thr Ala Val Met Val Val Leu Ile 
        835                 840                 845


Met Val Trp Asp Gly Ile Pro Leu Pro Met Ala Asp Arg Leu Tyr Thr 
    850                 855                 860


Glu Leu Thr Glu Asn Leu Lys Ser Tyr Asn Gly His Pro Thr Asp Arg 
865                 870                 875                 880


Arg Cys Thr Leu Asn Glu Asn Arg Thr Cys Thr Cys Gln Gly Ile Asp 
                885                 890                 895


Pro Glu Thr Cys Gly Ala Ser Phe Ser Phe Gly Cys Ser Trp Ser Met 
            900                 905                 910


Tyr Phe Asn Gly Cys Lys Phe Gly Arg Ser Pro Ser Pro Arg Arg Phe 
        915                 920                 925


Arg Ile Asp Pro Ser Ser Pro Leu His Glu Lys Asn Leu Glu Asp Asn 
    930                 935                 940


Leu Gln Ser Leu Ala Thr Arg Leu Ala Pro Ile Tyr Lys Gln Tyr Ala 
945                 950                 955                 960


Pro Val Ala Tyr Gln Asn Gln Val Glu Tyr Glu Asn Val Ala Arg Glu 
                965                 970                 975


Cys Arg Leu Gly Ser Lys Glu Gly Arg Pro Phe Ser Gly Val Thr Ala 
            980                 985                 990


Cys Leu Asp Phe Cys Ala His Pro His Arg Asp Ile His Asn Met Asn 
        995                 1000                1005


Asn Gly Ser Thr Val Val Cys Thr Leu Thr Arg Glu Asp Asn Arg Ser 
    1010                1015                1020


Leu Gly Val Ile Pro Gln Asp Glu Gln Leu His Val Leu Pro Leu Tyr 
1025                1030                1035                1040


Lys Leu Ser Asp Thr Asp Glu Phe Gly Ser Lys Glu Gly Met Glu Ala 
                1045                1050                1055


Lys Ile Lys Ser Gly Ala Ile Glu Val Leu Ala Pro Arg Arg Lys Lys 
            1060                1065                1070


Arg Thr Cys Phe Thr Gln Pro Val Pro Arg Ser Gly Lys Lys Arg Ala 
        1075                1080                1085


Ala Met Met Thr Glu Val Leu Ala His Lys Ile Arg Ala Val Glu Lys 
    1090                1095                1100


Lys Pro Ile Pro Arg Ile Lys Arg Lys Asn Asn Ser Thr Thr Thr Asn 
1105                1110                1115                1120


Asn Ser Lys Pro Ser Ser Leu Pro Thr Leu Gly Ser Asn Thr Glu Thr 
                1125                1130                1135


Val Gln Pro Glu Val Lys Ser Glu Thr Glu Pro His Phe Ile Leu Lys 
            1140                1145                1150


Ser Ser Asp Asn Thr Lys Thr Tyr Ser Leu Met Pro Ser Ala Pro His 
        1155                1160                1165


Pro Val Lys Glu Ala Ser Pro Gly Phe Ser Trp Ser Pro Lys Thr Ala 
    1170                1175                1180


Ser Ala Thr Pro Ala Pro Leu Lys Asn Asp Ala Thr Ala Ser Cys Gly 
1185                1190                1195                1200


Phe Ser Glu Arg Ser Ser Thr Pro His Cys Thr Met Pro Ser Gly Arg 
                1205                1210                1215


Leu Ser Gly Ala Asn Ala Ala Ala Ala Asp Gly Pro Gly Ile Ser Gln 
            1220                1225                1230


Leu Gly Glu Val Ala Pro Leu Pro Thr Leu Ser Ala Pro Val Met Glu 
        1235                1240                1245


Pro Leu Ile Asn Ser Glu Pro Ser Thr Gly Val Thr Glu Pro Leu Thr 
    1250                1255                1260


Pro His Gln Pro Asn His Gln Pro Ser Phe Leu Thr Ser Pro Gln Asp 
1265                1270                1275                1280


Leu Ala Ser Ser Pro Met Glu Glu Asp Glu Gln His Ser Glu Ala Asp 
                1285                1290                1295


Glu Pro Pro Ser Asp Glu Pro Leu Ser Asp Asp Pro Leu Ser Pro Ala 
            1300                1305                1310


Glu Glu Lys Leu Pro His Ile Asp Glu Tyr Trp Ser Asp Ser Glu His 
        1315                1320                1325


Ile Phe Leu Asp Ala Asn Ile Gly Gly Val Ala Ile Ala Pro Ala His 
    1330                1335                1340


Gly Ser Val Leu Ile Glu Cys Ala Arg Arg Glu Leu His Ala Thr Thr 
1345                1350                1355                1360


Pro Val Glu His Pro Asn Arg Asn His Pro Thr Arg Leu Ser Leu Val 
                1365                1370                1375


Phe Tyr Gln His Lys Asn Leu Asn Lys Pro Gln His Gly Phe Glu Leu 
            1380                1385                1390


Asn Lys Ile Lys Phe Glu Ala Lys Glu Ala Lys Asn Lys Lys Met Lys 
        1395                1400                1405


Ala Ser Glu Gln Lys Asp Gln Ala Ala Asn Glu Gly Pro Glu Gln Ser 
    1410                1415                1420


Ser Glu Val Asn Glu Leu Asn Gln Ile Pro Ser His Lys Ala Leu Thr 
1425                1430                1435                1440


Leu Thr His Asp Asn Val Val Thr Val Ser Pro Tyr Ala Leu Thr His 
                1445                1450                1455


Val Ala Gly Pro Tyr Asn His Trp Val 
            1460                1465


<210>  6944
<211>  1184
<212>  DNA
<213>  Homo sapiens

<400>  6944
aacctgaagt aaaaagtgaa accgaacccc attttatctt aaaaagttca gacaacacta     60

aaacttattc gctgatgcca tccgctcctc acccagtgaa agaggcatct ccaggcttct    120

cctggtcccc gaagactgct tcagccacac cagctccact gaagaatgac gcaacagcct    180

catgcgggtt ttcagaaaga agcagcactc cccactgtac gatgccttcg ggaagactca    240

gtggtgccaa tgcagctgct gctgatggcc ctggcatttc acagcttggc gaagtggctc    300

ctctccccac cctgtctgct cctgtgatgg agcccctcat taattctgag ccttccactg    360

gtgtgactga gccgctaacg cctcatcagc caaaccacca gccctccttc ctcacctctc    420

ctcaagacct tgcctcttct ccaatggaag aagatgagca gcattctgaa gcagatgagc    480

ctccatcaga cgaaccccta tctgatgacc ccctgtcacc tgctgaggag aaattgcccc    540

acattgatga gtattggtca gacagtgagc acatcttttt ggatgcaaat attggtgggg    600

tggccatcgc acctgctcac ggctcggttt tgattgagtg tgcccggcga gagctgcacg    660

ctaccactcc tgttgagcac cccaaccgta atcatccaac ccgcctctcc cttgtctttt    720

accagcacaa aaacctaaat aagccccaac atggttttga actaaacaag attaagtttg    780

aggctaaaga agctaagaat aagaaaatga aggcctcaga gcaaaaagac caggcagcta    840

atgaaggtcc agaacagtcc tctgaagtaa atgaattgaa ccaaattcct tctcataaag    900

cattaacatt aacccatgac aatgttgtca ccgtgtcccc ttatgctctc acacacgttg    960

cggggcccta taaccattgg gtctgaaggc ttttctcccc ctcttaatgc ctttgctagt   1020

gcagtgtatt ttttcaaggt gctgttaaaa gaaagtcatg ttgtcgttta ctatcttcat   1080

ctcacccatt tcaagtctga ggtaaaaaaa taataatgat aacaaaacgg ggtgggtatt   1140

cttaactgtg aagatatttg tactgaagtc tgatacagaa ttag                    1184


<210>  6945
<211>  303
<212>  PRT
<213>  Homo sapiens

<400>  6945

Met Pro Ser Ala Pro His Pro Val Lys Glu Ala Ser Pro Gly Phe Ser 
1               5                   10                  15


Trp Ser Pro Lys Thr Ala Ser Ala Thr Pro Ala Pro Leu Lys Asn Asp 
            20                  25                  30


Ala Thr Ala Ser Cys Gly Phe Ser Glu Arg Ser Ser Thr Pro His Cys 
        35                  40                  45


Thr Met Pro Ser Gly Arg Leu Ser Gly Ala Asn Ala Ala Ala Ala Asp 
    50                  55                  60


Gly Pro Gly Ile Ser Gln Leu Gly Glu Val Ala Pro Leu Pro Thr Leu 
65                  70                  75                  80


Ser Ala Pro Val Met Glu Pro Leu Ile Asn Ser Glu Pro Ser Thr Gly 
                85                  90                  95


Val Thr Glu Pro Leu Thr Pro His Gln Pro Asn His Gln Pro Ser Phe 
            100                 105                 110


Leu Thr Ser Pro Gln Asp Leu Ala Ser Ser Pro Met Glu Glu Asp Glu 
        115                 120                 125


Gln His Ser Glu Ala Asp Glu Pro Pro Ser Asp Glu Pro Leu Ser Asp 
    130                 135                 140


Asp Pro Leu Ser Pro Ala Glu Glu Lys Leu Pro His Ile Asp Glu Tyr 
145                 150                 155                 160


Trp Ser Asp Ser Glu His Ile Phe Leu Asp Ala Asn Ile Gly Gly Val 
                165                 170                 175


Ala Ile Ala Pro Ala His Gly Ser Val Leu Ile Glu Cys Ala Arg Arg 
            180                 185                 190


Glu Leu His Ala Thr Thr Pro Val Glu His Pro Asn Arg Asn His Pro 
        195                 200                 205


Thr Arg Leu Ser Leu Val Phe Tyr Gln His Lys Asn Leu Asn Lys Pro 
    210                 215                 220


Gln His Gly Phe Glu Leu Asn Lys Ile Lys Phe Glu Ala Lys Glu Ala 
225                 230                 235                 240


Lys Asn Lys Lys Met Lys Ala Ser Glu Gln Lys Asp Gln Ala Ala Asn 
                245                 250                 255


Glu Gly Pro Glu Gln Ser Ser Glu Val Asn Glu Leu Asn Gln Ile Pro 
            260                 265                 270


Ser His Lys Ala Leu Thr Leu Thr His Asp Asn Val Val Thr Val Ser 
        275                 280                 285


Pro Tyr Ala Leu Thr His Val Ala Gly Pro Tyr Asn His Trp Val 
    290                 295                 300


<210>  6946
<211>  3936
<212>  DNA
<213>  Homo sapiens

<400>  6946
agaacgtcag ccagtaagcg ccgttcctcc gggagatgtg gaggaggggg gcggcgtgga     60

ggaagagggg gaagttggcg catgcgccta aagctgacgg gtttgaaatg gcttcgatgt    120

tagccgggac ccgactcaga tcgatgctat agaagacaaa caagggaagg ttttttttcc    180

ttttgcatca tggctcaatt tggaggacag aagaatccgc catgggctac tcagtttaca    240

gccactgcag tatcacagcc agctgcactg ggtgttcaac agccatcact ccttggagca    300

tctcctacca tttatacaca gcaaactgca ttggcagcag caggccttac cacacaaact    360

ccagcaaact atcagttaac acaaactgct gcattgcagc aacaagccgc agctgcagca    420

gctgcattac aacagcaata ttcacaacct cagcaggccc tgtatagtgt gcaacaacag    480

ttacagcaac cccagcaaac cctcttaaca cagccagctg ttgcactgcc tacaagcctt    540

agcctgtcta ctcctcagcc aacagcacaa ataactgtat catatccaac accaaggtcc    600

agtcaacagc aaacccagcc tcagaagcag cgtgttttca caggggtggt tacaaaacta    660

catgatacgt ttggatttgt ggatgaagat gtattctttc agcttagtgc tgtcaaaggg    720

aaaacccccc aagtaggtga cagagtattg gttgaagcta cttataatcc taatatgcct    780

tttaaatgga atgcacagag aattcaaaca ctaccaaatc agaatcagtc gcaaacccag    840

ccattactga agactcctcc tgctgtactt cagccaattg caccacagac aacatttggt    900

gttcagactc agccccagcc ccagtcactg ctgcaggcac agatttcagc agcttctatt    960

acaccactat tgcagactca accacagccc ttattacagc agcctcagca aaaagctggt   1020

ttattgcagc ctcctgttcg tatagtttca cagccacaac cggcacgacg attagatccc   1080

ccatcccgat tttcaggaag aaatgacaga ggggatcaag tgcctaacag aaaagatgat   1140

cgaagtcgtg agagagagag agaaagacgt agatcgagag aaagatcacc tcagaggaaa   1200

cgttcccggg aaagatctcc acgaagagag cgagagcgat cacctcggag agttcgacgt   1260

gttgttccac gttacacagt tcagttttca aagttttctt tagattgtcc cagttgtgac   1320

atgatggaac taaggcgccg ttatcaaaat ttgtatatac ctagtgactt ttttgatgct   1380

caatttacat gggtggatgc tttccctttg tcaagaccat ttcagctggg aaattactgc   1440

aatttttatg taatgcacag agaagtagag tccttagaaa aaaatatggc cattcttgat   1500

ccaccagatg ctgaccactt atacagtgca aaggtaatgc tgatggctag ccctagtatg   1560

gaagatttat atcataagtc atgtgctctt gctgaggacc cacaagaact tcgagatgga   1620

ttccaacatc ctgctagact tgttaagttt ttagtgggca tgaaaggcaa ggatgaagct   1680

atggccattg gaggccactg gtctccttcg ttggatggac cagacccaga aaaagatccc   1740

tctgtgttga ttaagactgc tattcgttgt tgtaaggctc tgacaggcat tgatctaagt   1800

gtgtgcacac aatggtaccg ttttgcagag attcgctacc atcgccctga ggagacccac   1860

aaggggcgta cagttccagc tcatgtggag acagtggttt tatttttccc ggatgtttgg   1920

cattgccttc ccacccgctc agagtgggaa accctctccc gaggatacaa gcagcagctg   1980

gtcgagaagc ttcagggtga acgcaaggag gctgatggag aacaggatga agaagagaag   2040

gatgatggtg aagctaaaga aatttctaca cctacccatt ggtctaaact tgatccaaag   2100

acaatgaagg taaatgacct ccgaaaagaa ttagaaagtc gagctcttag ttccaaagga   2160

ttaaaatccc agttaatagc ccgattgaca aaacagctta aagtagagga acaaaaagaa   2220

gaacagaagg agttagagaa atctgaaaaa gaagaggatg aggatgatga taggaaatct   2280

gaagacgata aagaggaaga agaaaggaaa cgtcaagagg aaatagaacg ccagcgtcga   2340

gaaagaagat atattttgcc tgatgaaccg gccatcattg tacatccaaa ttgggctgca   2400

aaaagtggca agtttgattg tagcatcatg tctttgagtg tcctattgga ctacagatta   2460

gaggataata aagaacattc atttgaggtt tcattgtttg cggaactttt caacgaaatg   2520

cttcaaagag attttggtgt ccgtatatac aaatcattac tgtctcttcc tgagaaagag   2580

gacaaaaaag aaaaggataa aaaaagcaaa aaagatgaga gaaaagataa aaaagaagaa   2640

agagatgatg aaactgatga accaaaaccc aaacggagaa aatcaggcga tgataaagat   2700

aaaaaagaag atagagatga aaggaagaaa gaagataaaa gaaaagatga ttctaaagat   2760

gatgatgaaa ctgaagaaga taacaatcaa gatgaatatg accctatgga agcagaagaa   2820

gctgaggatg aagaagatga tagggatgag gaagaaatga ccaaacgaga tgacaaaaga   2880

gatatcaaca gatactgcaa ggagaggccc tctaaagata aggaaaaaga aaagactcaa   2940

atgatcacaa ttaacagaga tctgttaatg gcttttgttt attttgatca aagtcattgt   3000

ggttaccttc ttgaaaagga tttggaagaa atactttata ctcttggact acatctttct   3060

cgggctcagg taaagaagct tcttaataaa gtagtgctcc gtgaatcttg cttttaccgg   3120

aaattaacag acacctcaaa agatgaagag aaccatgaag agtctgagtc attgcaggaa   3180

gatatgctag gaaacagatt attacttcca acaccaacag taaagcagga atcaaaggat   3240

gtggaagaaa atgttggcct cattgtgtac aatggtgcaa tggtagatgt aggaagcctc   3300

ttgcaaaaat tggaaaagag cgaaaaagta agagctgagg tagaacagaa gctgcagtta   3360

ctagaagaaa aaacagatga agatgaaaaa accatattaa atttggagaa ttccaacaaa   3420

agcctctctg gtgaactcag agaagttaaa aaggacctta gtcagttaca agaaaactta   3480

aagatttcgg aaaacatgaa tttacaattt gaaaaccaaa tgaataagac aatcagaaac   3540

ttatctacgg taatggatga aatccacact gttctcaaga aggataatgt aaagaatgaa   3600

gacaaagatc aaaaatccaa ggagaatggt gccagtgtat gataaaatcc atgtagtgat   3660

gaggaatggt gttaaataat gtaatatata aaaatcatga tataagaatg tttgaaggtg   3720

atgcatgttt gattttagta gtataaatgt attttagttc aaatgatgta taaagtttta   3780

tgaatgtgag tttctgcttt tgaaaattgc ttgtaattcc tagccttcaa attattaaac   3840

actccttgag tgaaataatt ttgcattgca aagtgtttta ggatgaactt tgttatagtt   3900

ttaactccaa taaagttcat cagtttaatt gactgt                             3936


<210>  6947
<211>  1150
<212>  PRT
<213>  Homo sapiens

<400>  6947

Met Ala Gln Phe Gly Gly Gln Lys Asn Pro Pro Trp Ala Thr Gln Phe 
1               5                   10                  15


Thr Ala Thr Ala Val Ser Gln Pro Ala Ala Leu Gly Val Gln Gln Pro 
            20                  25                  30


Ser Leu Leu Gly Ala Ser Pro Thr Ile Tyr Thr Gln Gln Thr Ala Leu 
        35                  40                  45


Ala Ala Ala Gly Leu Thr Thr Gln Thr Pro Ala Asn Tyr Gln Leu Thr 
    50                  55                  60


Gln Thr Ala Ala Leu Gln Gln Gln Ala Ala Ala Ala Ala Ala Ala Leu 
65                  70                  75                  80


Gln Gln Gln Tyr Ser Gln Pro Gln Gln Ala Leu Tyr Ser Val Gln Gln 
                85                  90                  95


Gln Leu Gln Gln Pro Gln Gln Thr Leu Leu Thr Gln Pro Ala Val Ala 
            100                 105                 110


Leu Pro Thr Ser Leu Ser Leu Ser Thr Pro Gln Pro Thr Ala Gln Ile 
        115                 120                 125


Thr Val Ser Tyr Pro Thr Pro Arg Ser Ser Gln Gln Gln Thr Gln Pro 
    130                 135                 140


Gln Lys Gln Arg Val Phe Thr Gly Val Val Thr Lys Leu His Asp Thr 
145                 150                 155                 160


Phe Gly Phe Val Asp Glu Asp Val Phe Phe Gln Leu Ser Ala Val Lys 
                165                 170                 175


Gly Lys Thr Pro Gln Val Gly Asp Arg Val Leu Val Glu Ala Thr Tyr 
            180                 185                 190


Asn Pro Asn Met Pro Phe Lys Trp Asn Ala Gln Arg Ile Gln Thr Leu 
        195                 200                 205


Pro Asn Gln Asn Gln Ser Gln Thr Gln Pro Leu Leu Lys Thr Pro Pro 
    210                 215                 220


Ala Val Leu Gln Pro Ile Ala Pro Gln Thr Thr Phe Gly Val Gln Thr 
225                 230                 235                 240


Gln Pro Gln Pro Gln Ser Leu Leu Gln Ala Gln Ile Ser Ala Ala Ser 
                245                 250                 255


Ile Thr Pro Leu Leu Gln Thr Gln Pro Gln Pro Leu Leu Gln Gln Pro 
            260                 265                 270


Gln Gln Lys Ala Gly Leu Leu Gln Pro Pro Val Arg Ile Val Ser Gln 
        275                 280                 285


Pro Gln Pro Ala Arg Arg Leu Asp Pro Pro Ser Arg Phe Ser Gly Arg 
    290                 295                 300


Asn Asp Arg Gly Asp Gln Val Pro Asn Arg Lys Asp Asp Arg Ser Arg 
305                 310                 315                 320


Glu Arg Glu Arg Glu Arg Arg Arg Ser Arg Glu Arg Ser Pro Gln Arg 
                325                 330                 335


Lys Arg Ser Arg Glu Arg Ser Pro Arg Arg Glu Arg Glu Arg Ser Pro 
            340                 345                 350


Arg Arg Val Arg Arg Val Val Pro Arg Tyr Thr Val Gln Phe Ser Lys 
        355                 360                 365


Phe Ser Leu Asp Cys Pro Ser Cys Asp Met Met Glu Leu Arg Arg Arg 
    370                 375                 380


Tyr Gln Asn Leu Tyr Ile Pro Ser Asp Phe Phe Asp Ala Gln Phe Thr 
385                 390                 395                 400


Trp Val Asp Ala Phe Pro Leu Ser Arg Pro Phe Gln Leu Gly Asn Tyr 
                405                 410                 415


Cys Asn Phe Tyr Val Met His Arg Glu Val Glu Ser Leu Glu Lys Asn 
            420                 425                 430


Met Ala Ile Leu Asp Pro Pro Asp Ala Asp His Leu Tyr Ser Ala Lys 
        435                 440                 445


Val Met Leu Met Ala Ser Pro Ser Met Glu Asp Leu Tyr His Lys Ser 
    450                 455                 460


Cys Ala Leu Ala Glu Asp Pro Gln Glu Leu Arg Asp Gly Phe Gln His 
465                 470                 475                 480


Pro Ala Arg Leu Val Lys Phe Leu Val Gly Met Lys Gly Lys Asp Glu 
                485                 490                 495


Ala Met Ala Ile Gly Gly His Trp Ser Pro Ser Leu Asp Gly Pro Asp 
            500                 505                 510


Pro Glu Lys Asp Pro Ser Val Leu Ile Lys Thr Ala Ile Arg Cys Cys 
        515                 520                 525


Lys Ala Leu Thr Gly Ile Asp Leu Ser Val Cys Thr Gln Trp Tyr Arg 
    530                 535                 540


Phe Ala Glu Ile Arg Tyr His Arg Pro Glu Glu Thr His Lys Gly Arg 
545                 550                 555                 560


Thr Val Pro Ala His Val Glu Thr Val Val Leu Phe Phe Pro Asp Val 
                565                 570                 575


Trp His Cys Leu Pro Thr Arg Ser Glu Trp Glu Thr Leu Ser Arg Gly 
            580                 585                 590


Tyr Lys Gln Gln Leu Val Glu Lys Leu Gln Gly Glu Arg Lys Glu Ala 
        595                 600                 605


Asp Gly Glu Gln Asp Glu Glu Glu Lys Asp Asp Gly Glu Ala Lys Glu 
    610                 615                 620


Ile Ser Thr Pro Thr His Trp Ser Lys Leu Asp Pro Lys Thr Met Lys 
625                 630                 635                 640


Val Asn Asp Leu Arg Lys Glu Leu Glu Ser Arg Ala Leu Ser Ser Lys 
                645                 650                 655


Gly Leu Lys Ser Gln Leu Ile Ala Arg Leu Thr Lys Gln Leu Lys Val 
            660                 665                 670


Glu Glu Gln Lys Glu Glu Gln Lys Glu Leu Glu Lys Ser Glu Lys Glu 
        675                 680                 685


Glu Asp Glu Asp Asp Asp Arg Lys Ser Glu Asp Asp Lys Glu Glu Glu 
    690                 695                 700


Glu Arg Lys Arg Gln Glu Glu Ile Glu Arg Gln Arg Arg Glu Arg Arg 
705                 710                 715                 720


Tyr Ile Leu Pro Asp Glu Pro Ala Ile Ile Val His Pro Asn Trp Ala 
                725                 730                 735


Ala Lys Ser Gly Lys Phe Asp Cys Ser Ile Met Ser Leu Ser Val Leu 
            740                 745                 750


Leu Asp Tyr Arg Leu Glu Asp Asn Lys Glu His Ser Phe Glu Val Ser 
        755                 760                 765


Leu Phe Ala Glu Leu Phe Asn Glu Met Leu Gln Arg Asp Phe Gly Val 
    770                 775                 780


Arg Ile Tyr Lys Ser Leu Leu Ser Leu Pro Glu Lys Glu Asp Lys Lys 
785                 790                 795                 800


Glu Lys Asp Lys Lys Ser Lys Lys Asp Glu Arg Lys Asp Lys Lys Glu 
                805                 810                 815


Glu Arg Asp Asp Glu Thr Asp Glu Pro Lys Pro Lys Arg Arg Lys Ser 
            820                 825                 830


Gly Asp Asp Lys Asp Lys Lys Glu Asp Arg Asp Glu Arg Lys Lys Glu 
        835                 840                 845


Asp Lys Arg Lys Asp Asp Ser Lys Asp Asp Asp Glu Thr Glu Glu Asp 
    850                 855                 860


Asn Asn Gln Asp Glu Tyr Asp Pro Met Glu Ala Glu Glu Ala Glu Asp 
865                 870                 875                 880


Glu Glu Asp Asp Arg Asp Glu Glu Glu Met Thr Lys Arg Asp Asp Lys 
                885                 890                 895


Arg Asp Ile Asn Arg Tyr Cys Lys Glu Arg Pro Ser Lys Asp Lys Glu 
            900                 905                 910


Lys Glu Lys Thr Gln Met Ile Thr Ile Asn Arg Asp Leu Leu Met Ala 
        915                 920                 925


Phe Val Tyr Phe Asp Gln Ser His Cys Gly Tyr Leu Leu Glu Lys Asp 
    930                 935                 940


Leu Glu Glu Ile Leu Tyr Thr Leu Gly Leu His Leu Ser Arg Ala Gln 
945                 950                 955                 960


Val Lys Lys Leu Leu Asn Lys Val Val Leu Arg Glu Ser Cys Phe Tyr 
                965                 970                 975


Arg Lys Leu Thr Asp Thr Ser Lys Asp Glu Glu Asn His Glu Glu Ser 
            980                 985                 990


Glu Ser Leu Gln Glu Asp Met Leu Gly Asn Arg Leu Leu Leu Pro Thr 
        995                 1000                1005


Pro Thr Val Lys Gln Glu Ser Lys Asp Val Glu Glu Asn Val Gly Leu 
    1010                1015                1020


Ile Val Tyr Asn Gly Ala Met Val Asp Val Gly Ser Leu Leu Gln Lys 
1025                1030                1035                1040


Leu Glu Lys Ser Glu Lys Val Arg Ala Glu Val Glu Gln Lys Leu Gln 
                1045                1050                1055


Leu Leu Glu Glu Lys Thr Asp Glu Asp Glu Lys Thr Ile Leu Asn Leu 
            1060                1065                1070


Glu Asn Ser Asn Lys Ser Leu Ser Gly Glu Leu Arg Glu Val Lys Lys 
        1075                1080                1085


Asp Leu Ser Gln Leu Gln Glu Asn Leu Lys Ile Ser Glu Asn Met Asn 
    1090                1095                1100


Leu Gln Phe Glu Asn Gln Met Asn Lys Thr Ile Arg Asn Leu Ser Thr 
1105                1110                1115                1120


Val Met Asp Glu Ile His Thr Val Leu Lys Lys Asp Asn Val Lys Asn 
                1125                1130                1135


Glu Asp Lys Asp Gln Lys Ser Lys Glu Asn Gly Ala Ser Val 
            1140                1145                1150


<210>  6948
<211>  4751
<212>  DNA
<213>  Homo sapiens

<400>  6948
agaacgtcag ccagtaagcg ccgttcctcc gggagatgtg gaggaggggg gcggcgtgga     60

ggaagagggg gaagttggcg catgcgccta aagctgacgg gtttgaaatg gcttcgatgt    120

tagccgggac ccgactcaga tcgatgctat agaagacaaa caagggaagg ttttttttcc    180

ttttgcatca tggctcaatt tggaggacag aagaatccgc catgggctac tcagtttaca    240

gccactgcag tatcacagcc agctgcactg ggtgttcaac agccatcact ccttggagca    300

tctcctacca tttatacaca gcaaactgca ttggcagcag caggccttac cacacaaact    360

ccagcaaact atcagttaac acaaactgct gcattgcagc aacaagccgc agctgcagca    420

gctgcattac aacagcaata ttcacaacct cagcaggccc tgtatagtgt gcaacaacag    480

ttacagcaac cccagcaaac cctcttaaca cagccagctg ttgcactgcc tacaagcctt    540

agcctgtcta ctcctcagcc aacagcacaa ataactgtat catatccaac accaaggtcc    600

agtcaacagc aaacccagcc tcagaagcag cgtgttttca caggggtggt tacaaaacta    660

catgatacgt ttggatttgt ggatgaagat gtattctttc agcttagtgc tgtcaaaggg    720

aaaacccccc aagtaggtga cagagtattg gttgaagcta cttataatcc taatatgcct    780

tttaaatgga atgcacagag aattcaaaca ctaccaaatc agaatcagtc gcaaacccag    840

ccattactga agactcctcc tgctgtactt cagccaattg caccacagac aacatttggt    900

gttcagactc agccccagcc ccagtcactg ctgcaggcac agatttcagc agcttctatt    960

acaccactat tgcagactca accacagccc ttattacagc agcctcagca aaaagctggt   1020

ttattgcagc ctcctgttcg tatagtttca cagccacaac cggcacgacg attagatccc   1080

ccatcccgat tttcaggaag aaatgacaga ggggatcaag tgcctaacag aaaagatgat   1140

cgaagtcgtg agagagagag agaaagacgt agatcgagag aaagatcacc tcagaggaaa   1200

cgttcccggg aaagatctcc acgaagagag cgagagcgat cacctcggag agttcgacgt   1260

gttgttccac gttacacagt tcagttttca aagttttctt tagattgtcc cagttgtgac   1320

atgatggaac taaggcgccg ttatcaaaat ttgtatatac ctagtgactt ttttgatgct   1380

caatttacat gggtggatgc tttccctttg tcaagaccat ttcagctggg aaattactgc   1440

aatttttatg taatgcacag agaagtagag tccttagaaa aaaatatggc cattcttgat   1500

ccaccagatg ctgaccactt atacagtgca aaggtaatgc tgatggctag ccctagtatg   1560

gaagatttat atcataagtc atgtgctctt gctgaggacc cacaagaact tcgagatgga   1620

ttccaacatc ctgctagact tgttaagttt ttagtgggca tgaaaggcaa ggatgaagct   1680

atggccattg gaggccactg gtctccttcg ttggatggac cagacccaga aaaagatccc   1740

tctgtgttga ttaagactgc tattcgttgt tgtaaggctc tgacaggcat tgatctaagt   1800

gtgtgcacac aatggtaccg ttttgcagag attcgctacc atcgccctga ggagacccac   1860

aaggggcgta cagttccagc tcatgtggag acagtggttt tatttttccc ggatgtttgg   1920

cattgccttc ccacccgctc agagtgggaa accctctccc gaggatacaa gcagcagctg   1980

gtcgagaagc ttcagggtga acgcaaggag gctgatggag aacaggatga agaagagaag   2040

gatgatggtg aagctaaaga aatttctaca cctacccatt ggtctaaact tgatccaaag   2100

acaatgaagg taaatgacct ccgaaaagaa ttagaaagtc gagctcttag ttccaaagga   2160

ttaaaatccc agttaatagc ccgattgaca aaacagctta aagtagagga acaaaaagaa   2220

gaacagaagg agttagagaa atctgaaaaa gaagaggatg aggatgatga taggaaatct   2280

gaagacgata aagaggaaga agaaaggaaa cgtcaagagg aaatagaacg ccagcgtcga   2340

gaaagaagat atattttgcc tgatgaaccg gccatcattg tacatccaaa ttgggctgca   2400

aaaagtggca agtttgattg tagcatcatg tctttgagtg tcctattgga ctacagatta   2460

gaggataata aagaacattc atttgaggtt tcattgtttg cggaactttt caacgaaatg   2520

cttcaaagag attttggtgt ccgtatatac aaatcattac tgtctcttcc tgagaaagag   2580

gacaaaaaag aaaaggataa aaaaagcaaa aaagatgaga gaaaagataa aaaagaagaa   2640

agagatgatg aaactgatga accaaaaccc aaacggagaa aatcaggcga tgataaagat   2700

aaaaaagaag atagagatga aaggaagaaa gaagataaaa gaaaagatga ttctaaagat   2760

gatgatgaaa ctgaagaaga taacaatcaa gatgaatatg accctatgga agcagaagaa   2820

gctgaggatg aagaagatga tagggatgag gaagaaatga ccaaacgaga tgacaaaaga   2880

gatatcaaca gatactgcaa ggagaggccc tctaaagata aggaaaaaga aaagactcaa   2940

atgatcacaa ttaacagaga tctgttaatg gcttttgttt attttgatca aagtcattgt   3000

ggttaccttc ttgaaaagga tttggaagaa atactttata ctcttggact acatctttct   3060

cgggctcagg taaagaagct tcttaataaa gtagtgctcc gtgaatcttg cttttaccgg   3120

aaattaacag acacctcaaa agatgaagag aaccatgaag agtctgagtc attgcaggaa   3180

gatatgctag gaaacagatt attacttcca acaccaacag taaagcagga atcaaaggat   3240

gtggaagaaa atgttggcct cattgtgtac aatggtgcaa tggtagatgt aggaagcctc   3300

ttgcaaaaat tggaaaagag cgaaaaagta agagctgagg tagaacagaa gctgcagtta   3360

ctagaagaaa aaacagatga agatgaaaaa accatattaa atttggagaa ttccaacaaa   3420

agcctctctg gtgaactcag agaagttaaa aaggacctta gtcagttaca agaaaactta   3480

aagatttcgg aaaacatgaa tttacaattt gaaaaccaaa tgaataagac aatcagaaac   3540

ttatctacgg taatggatga aatccacact gttctcaaga aggataatgt aaagaatgaa   3600

gacaaagatc aaaaatccaa ggagaatggt gccagtgtat gataaaatcc atgtagtgat   3660

gaggaatggt gttaaataat gtaatatata aaaatcatga tataagaatg tttgaaggtg   3720

atgcatgttt gattttagta gtataaatgt attttagttc aaatgatgta taaagtttta   3780

tgaatgtgag tttctgcttt tgaaaattgc ttgtaattcc tagccttcaa attattaaac   3840

actccttgag tgaaataatt ttgcattgca aagtgtttta ggatgaactt tgttatagtt   3900

ttaactccaa taaagttcat cagtttaatt gactgtagta tttaattacc aaatttcttt   3960

tattaaaatg cctagaaatt tttaatttat agaattatta ggttttaaaa tttttagttc   4020

atctgttaaa atttcagtca aaatcataaa atagcatgat gcttaatttt tgcaagtttt   4080

ttgaaacttt ttgttttttt tactcatcac caaaaaatcc cctcttgatc agtctctaaa   4140

agcattcatt aaaaattcag ttcaggccgg gcacggtggc tcacacctgt aatcccaaca   4200

ctttgggagg ccgaggcagg tggatcacct gaggttagga gttcgagacc agcctggcca   4260

acatggtgaa acccggtctc tactaaaaat ataaaaatta gctgggcatg gtggtgggtg   4320

cctgtaatcc cagctacttg ggaggctgag gcaggagaat cgcttgaacc caggaggcgg   4380

aggttgcagt cactcaggat catgcagcta cactccagcc tgggcgacaa gagtgaaact   4440

ccatctcaaa aagaaaaaaa aaaaaaatca gtttatttga aagacagtat atcagaaaga   4500

aagaagcaat agagaactag tattgttctt tatgggttag actttacata atattagttg   4560

tcctgatgtc aatgttactg ctttcaatta atttttctac tttcccagaa tagcatctat   4620

attcctttta attttgaggg tttaaaaaaa aatgcagtgt atgtcaaatt tacagtttag   4680

taccaagcca gtagatgtca gtatgatgcc ttaaattaag tcttctttaa ttaaagatat   4740

ttttttaaat t                                                        4751


<210>  6949
<211>  1150
<212>  PRT
<213>  Homo sapiens

<400>  6949

Met Ala Gln Phe Gly Gly Gln Lys Asn Pro Pro Trp Ala Thr Gln Phe 
1               5                   10                  15


Thr Ala Thr Ala Val Ser Gln Pro Ala Ala Leu Gly Val Gln Gln Pro 
            20                  25                  30


Ser Leu Leu Gly Ala Ser Pro Thr Ile Tyr Thr Gln Gln Thr Ala Leu 
        35                  40                  45


Ala Ala Ala Gly Leu Thr Thr Gln Thr Pro Ala Asn Tyr Gln Leu Thr 
    50                  55                  60


Gln Thr Ala Ala Leu Gln Gln Gln Ala Ala Ala Ala Ala Ala Ala Leu 
65                  70                  75                  80


Gln Gln Gln Tyr Ser Gln Pro Gln Gln Ala Leu Tyr Ser Val Gln Gln 
                85                  90                  95


Gln Leu Gln Gln Pro Gln Gln Thr Leu Leu Thr Gln Pro Ala Val Ala 
            100                 105                 110


Leu Pro Thr Ser Leu Ser Leu Ser Thr Pro Gln Pro Thr Ala Gln Ile 
        115                 120                 125


Thr Val Ser Tyr Pro Thr Pro Arg Ser Ser Gln Gln Gln Thr Gln Pro 
    130                 135                 140


Gln Lys Gln Arg Val Phe Thr Gly Val Val Thr Lys Leu His Asp Thr 
145                 150                 155                 160


Phe Gly Phe Val Asp Glu Asp Val Phe Phe Gln Leu Ser Ala Val Lys 
                165                 170                 175


Gly Lys Thr Pro Gln Val Gly Asp Arg Val Leu Val Glu Ala Thr Tyr 
            180                 185                 190


Asn Pro Asn Met Pro Phe Lys Trp Asn Ala Gln Arg Ile Gln Thr Leu 
        195                 200                 205


Pro Asn Gln Asn Gln Ser Gln Thr Gln Pro Leu Leu Lys Thr Pro Pro 
    210                 215                 220


Ala Val Leu Gln Pro Ile Ala Pro Gln Thr Thr Phe Gly Val Gln Thr 
225                 230                 235                 240


Gln Pro Gln Pro Gln Ser Leu Leu Gln Ala Gln Ile Ser Ala Ala Ser 
                245                 250                 255


Ile Thr Pro Leu Leu Gln Thr Gln Pro Gln Pro Leu Leu Gln Gln Pro 
            260                 265                 270


Gln Gln Lys Ala Gly Leu Leu Gln Pro Pro Val Arg Ile Val Ser Gln 
        275                 280                 285


Pro Gln Pro Ala Arg Arg Leu Asp Pro Pro Ser Arg Phe Ser Gly Arg 
    290                 295                 300


Asn Asp Arg Gly Asp Gln Val Pro Asn Arg Lys Asp Asp Arg Ser Arg 
305                 310                 315                 320


Glu Arg Glu Arg Glu Arg Arg Arg Ser Arg Glu Arg Ser Pro Gln Arg 
                325                 330                 335


Lys Arg Ser Arg Glu Arg Ser Pro Arg Arg Glu Arg Glu Arg Ser Pro 
            340                 345                 350


Arg Arg Val Arg Arg Val Val Pro Arg Tyr Thr Val Gln Phe Ser Lys 
        355                 360                 365


Phe Ser Leu Asp Cys Pro Ser Cys Asp Met Met Glu Leu Arg Arg Arg 
    370                 375                 380


Tyr Gln Asn Leu Tyr Ile Pro Ser Asp Phe Phe Asp Ala Gln Phe Thr 
385                 390                 395                 400


Trp Val Asp Ala Phe Pro Leu Ser Arg Pro Phe Gln Leu Gly Asn Tyr 
                405                 410                 415


Cys Asn Phe Tyr Val Met His Arg Glu Val Glu Ser Leu Glu Lys Asn 
            420                 425                 430


Met Ala Ile Leu Asp Pro Pro Asp Ala Asp His Leu Tyr Ser Ala Lys 
        435                 440                 445


Val Met Leu Met Ala Ser Pro Ser Met Glu Asp Leu Tyr His Lys Ser 
    450                 455                 460


Cys Ala Leu Ala Glu Asp Pro Gln Glu Leu Arg Asp Gly Phe Gln His 
465                 470                 475                 480


Pro Ala Arg Leu Val Lys Phe Leu Val Gly Met Lys Gly Lys Asp Glu 
                485                 490                 495


Ala Met Ala Ile Gly Gly His Trp Ser Pro Ser Leu Asp Gly Pro Asp 
            500                 505                 510


Pro Glu Lys Asp Pro Ser Val Leu Ile Lys Thr Ala Ile Arg Cys Cys 
        515                 520                 525


Lys Ala Leu Thr Gly Ile Asp Leu Ser Val Cys Thr Gln Trp Tyr Arg 
    530                 535                 540


Phe Ala Glu Ile Arg Tyr His Arg Pro Glu Glu Thr His Lys Gly Arg 
545                 550                 555                 560


Thr Val Pro Ala His Val Glu Thr Val Val Leu Phe Phe Pro Asp Val 
                565                 570                 575


Trp His Cys Leu Pro Thr Arg Ser Glu Trp Glu Thr Leu Ser Arg Gly 
            580                 585                 590


Tyr Lys Gln Gln Leu Val Glu Lys Leu Gln Gly Glu Arg Lys Glu Ala 
        595                 600                 605


Asp Gly Glu Gln Asp Glu Glu Glu Lys Asp Asp Gly Glu Ala Lys Glu 
    610                 615                 620


Ile Ser Thr Pro Thr His Trp Ser Lys Leu Asp Pro Lys Thr Met Lys 
625                 630                 635                 640


Val Asn Asp Leu Arg Lys Glu Leu Glu Ser Arg Ala Leu Ser Ser Lys 
                645                 650                 655


Gly Leu Lys Ser Gln Leu Ile Ala Arg Leu Thr Lys Gln Leu Lys Val 
            660                 665                 670


Glu Glu Gln Lys Glu Glu Gln Lys Glu Leu Glu Lys Ser Glu Lys Glu 
        675                 680                 685


Glu Asp Glu Asp Asp Asp Arg Lys Ser Glu Asp Asp Lys Glu Glu Glu 
    690                 695                 700


Glu Arg Lys Arg Gln Glu Glu Ile Glu Arg Gln Arg Arg Glu Arg Arg 
705                 710                 715                 720


Tyr Ile Leu Pro Asp Glu Pro Ala Ile Ile Val His Pro Asn Trp Ala 
                725                 730                 735


Ala Lys Ser Gly Lys Phe Asp Cys Ser Ile Met Ser Leu Ser Val Leu 
            740                 745                 750


Leu Asp Tyr Arg Leu Glu Asp Asn Lys Glu His Ser Phe Glu Val Ser 
        755                 760                 765


Leu Phe Ala Glu Leu Phe Asn Glu Met Leu Gln Arg Asp Phe Gly Val 
    770                 775                 780


Arg Ile Tyr Lys Ser Leu Leu Ser Leu Pro Glu Lys Glu Asp Lys Lys 
785                 790                 795                 800


Glu Lys Asp Lys Lys Ser Lys Lys Asp Glu Arg Lys Asp Lys Lys Glu 
                805                 810                 815


Glu Arg Asp Asp Glu Thr Asp Glu Pro Lys Pro Lys Arg Arg Lys Ser 
            820                 825                 830


Gly Asp Asp Lys Asp Lys Lys Glu Asp Arg Asp Glu Arg Lys Lys Glu 
        835                 840                 845


Asp Lys Arg Lys Asp Asp Ser Lys Asp Asp Asp Glu Thr Glu Glu Asp 
    850                 855                 860


Asn Asn Gln Asp Glu Tyr Asp Pro Met Glu Ala Glu Glu Ala Glu Asp 
865                 870                 875                 880


Glu Glu Asp Asp Arg Asp Glu Glu Glu Met Thr Lys Arg Asp Asp Lys 
                885                 890                 895


Arg Asp Ile Asn Arg Tyr Cys Lys Glu Arg Pro Ser Lys Asp Lys Glu 
            900                 905                 910


Lys Glu Lys Thr Gln Met Ile Thr Ile Asn Arg Asp Leu Leu Met Ala 
        915                 920                 925


Phe Val Tyr Phe Asp Gln Ser His Cys Gly Tyr Leu Leu Glu Lys Asp 
    930                 935                 940


Leu Glu Glu Ile Leu Tyr Thr Leu Gly Leu His Leu Ser Arg Ala Gln 
945                 950                 955                 960


Val Lys Lys Leu Leu Asn Lys Val Val Leu Arg Glu Ser Cys Phe Tyr 
                965                 970                 975


Arg Lys Leu Thr Asp Thr Ser Lys Asp Glu Glu Asn His Glu Glu Ser 
            980                 985                 990


Glu Ser Leu Gln Glu Asp Met Leu Gly Asn Arg Leu Leu Leu Pro Thr 
        995                 1000                1005


Pro Thr Val Lys Gln Glu Ser Lys Asp Val Glu Glu Asn Val Gly Leu 
    1010                1015                1020


Ile Val Tyr Asn Gly Ala Met Val Asp Val Gly Ser Leu Leu Gln Lys 
1025                1030                1035                1040


Leu Glu Lys Ser Glu Lys Val Arg Ala Glu Val Glu Gln Lys Leu Gln 
                1045                1050                1055


Leu Leu Glu Glu Lys Thr Asp Glu Asp Glu Lys Thr Ile Leu Asn Leu 
            1060                1065                1070


Glu Asn Ser Asn Lys Ser Leu Ser Gly Glu Leu Arg Glu Val Lys Lys 
        1075                1080                1085


Asp Leu Ser Gln Leu Gln Glu Asn Leu Lys Ile Ser Glu Asn Met Asn 
    1090                1095                1100


Leu Gln Phe Glu Asn Gln Met Asn Lys Thr Ile Arg Asn Leu Ser Thr 
1105                1110                1115                1120


Val Met Asp Glu Ile His Thr Val Leu Lys Lys Asp Asn Val Lys Asn 
                1125                1130                1135


Glu Asp Lys Asp Gln Lys Ser Lys Glu Asn Gly Ala Ser Val 
            1140                1145                1150


<210>  6950
<211>  3886
<212>  DNA
<213>  Homo sapiens

<400>  6950
acgataagtg atttttttgt gactggcttc ttttacttag cctgttatca aggttcatgt     60

atgttttagc ataaggtttt ctctttatgt ttttgttgtt gttgtttaaa agacagggtc    120

ttgatctgtc acccagactg gagtgcagtg gtatagtcat agctcactac accctcgaac    180

gcctggccct cctgagtagc tgggataaca gtcatgtgcc actgtgccca cttgaaagta    240

tgtgtattaa tgactttttt gccactgtta tatttatttt acagataggg atgaggaaga    300

aatgaccaaa cgagatgaca aaagagatat caacagatac tgcaaggaga ggccctctaa    360

agataaggtg tttattgaat actgtattct ttataatatg gtgatatctt acatcatcta    420

aacataacac agttgtgaag tttattagtc cttatacatc tttattacca ctaagtaaaa    480

ttctgtcagt tgtttttttg tggctatgtc agataactag tatgtctgat tcttttctct    540

catattcgta taccagataa actcatttta gctaggatga ggcaaatatc ttattagatt    600

attgctatct tatgcacagt ctccgtttct cactttttgg gggtaaaaaa tttgaaattt    660

gaatactatg ttttctactt ctccattttc ttaggaaaaa gaaaagactc aaatgatcac    720

aattaacaga gatctgttaa tggcttttgt ttattttgat caaagtcatt gtggttacct    780

tcttgaaaag gatttggaag aaatacttta tactcttgga ctacatcttt ctcgggctca    840

ggtaatctat cttgtgaata tttaaaagga aaacattttt taaaagttac ctttccagtg    900

aaaagttaat agaacctctg ttgacttttt gatatattaa agcaatataa gggccaggcg    960

tggtggctca cacctataat cccagcaggt tgggaggctg aggcgggcag atcagttgag   1020

gccaggagtt taagaccagc ttggccaaca tggcgtagct ccgtctctac taaaaatgca   1080

aaaattagct gggtgtggtg gcacacgcct gtaatcccag ctactcggga agctgagaca   1140

ggagaatctc ttgaacccag gaggtggagg ttgcaatgag ccaagatcac gccactgcac   1200

tccagcctgg gtgacagagt gagactccat ctcaaaaaat aaaaataaag caatataaca   1260

caagccagtt gtaaaacact tcccttctcc ctctccctct gtttctactc cttaggacta   1320

caatatataa aattctagat ctttttgtaa gcagctcagt tccattttta taaacaaaac   1380

gtggaattat tctgtacgtt ttgactggct tttttttttt cattccacag tattctatag   1440

atacattcac catgaaaata gagacctgcc tcattctttt tatagctgca cagtacccat   1500

tatacagatg taccataatt tacctaccta gtctccattg ctggtggttt tcatttattg   1560

gatttaccaa ctatgctgta ataaatcatc cctgtgcata aatttttatc aatgttatac   1620

tttttaacaa tgaagttttt tttttcaaaa gtaacttgga tcttactcaa ttccatggat   1680

ttccatcata agtgaaaatt acagctgggc atagtggctc acacctgtaa tcccagcact   1740

ttgggaggcg gaggagggtg gatcacctga ggtcaggagt tcaagaccag cctggctaac   1800

atggtgaaac cctgtctctc caaaaataca aaaattggcc aggcatgcgc caccatgccc   1860

agctattttt tgtattttta gtagaaatgg ggtttcacca tgttggccag gatggtctca   1920

aactcctgac ctcaagggat cacccacttt ggcctcctat agtgttggga ttacaggcag   1980

gagccaccat gctctgcagg gacctttact tttcactatt tctggttcag gttataaaat   2040

tgcttagctt tatctgaatc ttaggtcttc ctgtgtattc tcaggttcat tgttacctgt   2100

tgcatccttt taatcatctt ctggttccac tttttttttt ttgagacaga gttttgccct   2160

gtcacccagg ctggagtgca gtggggctat cttggcccat tgcaacctcc acctcccaag   2220

ttcaagcgat tctcctgcct cagcctccca agtagctggg actacaggtg cgtgtcacca   2280

cgcctggcta attttttgta tttttagtag agacagggtt tcaccatgtt tgctaggatg   2340

gtctcgatct cctgacctcg tgatccgccc acctcagcct cccaaagtgc tgggtttaca   2400

ggcatgagcc actgcgcctg gcctccactt agtttttacc agtctgtgtt ctctaatcta   2460

tacagtcatc taaaaataga acataggttt tgaaataata caagttaaaa atttaaatga   2520

aacaggccag gcatggtggc tcccgcctgt aatcccagca ctttgggagg ccgaggcagg   2580

cagattgttt gaggtcagga gttcgagacc agcctgacca acatggtgaa accccgtctc   2640

taaaaataca aaaattagct gggtgtggtg gtacgcgcct gtaatcccag ccaagatcgt   2700

gccacttcgc tcaagctggc gcaacagagt gagactcagt ctcaaaagta aatacataaa   2760

taaatgaata ttgcagtgtg ctttatgact aatgaaattg acagacattg ccattttatg   2820

gaattctatc agctttttat tttcacagct taaatatttt aacctcaaag ttaaatttga   2880

aattttagga agtaaaatgt taatttttgg atttttttaa acagatgaag atgaaaaaac   2940

catattaaat ttggagaatt ccaacaaaag cctctctggt gaactcagag aagttaaaaa   3000

ggaccttagt cagttacaag aaaacttaaa gatttcggaa aacatgaatt tacaatttga   3060

aaaccaaatg aataagacaa tcagaaactt atctacggta atggatgaaa tccacactgt   3120

tctcaagaag gtgagaaatt ttgtactttt aacattttct tagttttaaa aatctaactc   3180

tggtgttttt aatgtatttt aatgttatta agctcttagt gattattcta aaagcaaata   3240

atgatagcat tgtgaccttc ctgagattag taaaaagtga ttcacaggct gggcacagtg   3300

gctcacacct gtaatcccag cactttggga ggccaacgcg ggcggatcac ctgaggtcag   3360

gagttcaagt ccagcctcgc caacgtggtg aaaccccatg tctactaaaa atacaaaaaa   3420

aattatgatt cccaaaagat gttgtttttc taaatcttag ttggaatgtc aacatgattt   3480

aagtatacag acttcttgaa gcaaatttca tttttatttc tttttaatcc agagtataaa   3540

tttgaattaa accattcact tcacttctct gtgttttttt tgttttgttt tgtctttttg   3600

agacagggtc ttgcactttt gcccaggctg gtttgttagt ggcgctatct tggctcactg   3660

cagcctctgc ctcctaggct cacgtgatcc tcccacctca gcctcctgat gagctgggac   3720

tacaggtgtg ctccagcaca cccagctaat ttttatattt tttttagaga cagggtttca   3780

gaccgggcgc ggtggctcat gcctgtaatc tcagcacttt cggaggccaa ggtgggcgga   3840

tcacgaagtc aggagattga gaccacagta aaaccccgtc tctact                  3886


<210>  6951
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  6951

Met Phe Leu Leu Leu Leu Phe Lys Arg Gln Gly Leu Asp Leu Ser Pro 
1               5                   10                  15


Arg Leu Glu Cys Ser Gly Ile Val Ile Ala His Tyr Thr Leu Glu Arg 
            20                  25                  30


Leu Ala Leu Leu Ser Ser Trp Asp Asn Ser His Val Pro Leu Cys Pro 
        35                  40                  45


Leu Glu Ser Met Cys Ile Asn Asp Phe Phe Ala Thr Val Ile Phe Ile 
    50                  55                  60


Leu Gln Ile Gly Met Arg Lys Lys 
65                  70


<210>  6952
<211>  3738
<212>  DNA
<213>  Homo sapiens

<400>  6952
gcgcgcgccc cccgcctgcc tgcaggtgct gcgcgatgcc tggcggcgcc gggccctgcg     60

gccgccgcgc ggcttccgca tcagggcggt gggtgatgtc tttccagtgc aaatgaatcc    120

aataactcaa tctcagttcg tacctttggg tgaagttctt tgctgtgcta tatctgatat    180

gaatacagct cagattgtag taacgcagga atcacttttg gagcgtttga tgaaacatta    240

cccaggcatt gcaattccat cggaagatat tctttatacc actctgggaa cgctgattaa    300

agaaaggaag atttatcaca ctggagaagg atacttcata gttactcctc agacttactt    360

cattacaaat acaaccaccc aggaaaataa gagaatgctg ccatcagatg aaagtcgcct    420

gatgccagct tccatgacat atctggtgag catggagagc tgtgcagagt cagcccaaga    480

gaatgctgcc cccatatccc actgtcagtc ttgccagtgt ttccgggaca tgcacactca    540

ggatgttcag gaagcaccag ttgctgcaga agtgactagg aagagtcaca gaggtcttgg    600

ggaatccgta tcttgggtac agaatggggc agtttcagtg tctgcggagc accacatttg    660

tgagagcacc aaacctttac catacacaag agataaagaa aaaggcaaga agtttggttt    720

tagtctctta tggcgcagct tatctagaaa ggagaagccc aaaacagaac acagcagttt    780

ctctgctcag ttcccacctg aagaatggcc cgtccgagat gaagatgact tggacaatat    840

ccctcgagat gttgaacatg agataatcaa acgaattaac cccattttga ctgttgacaa    900

tttaatcaaa cacactgtcc taatgcaaaa atacgaagaa cagaaaaaat ataatagcca    960

gggcacttcc actgacatgc tgacaatcgg gcataagtat ccttcaaaag agggggttaa   1020

gaaaaggcag ggtctgtctg caaaacctca agggcagggc cattctcgaa gggatagaca   1080

caaagccagg aatcagggaa gtgagtttca gccaggaagc attagactgg agaaacaccc   1140

caagctccct gctacacagc ccatccccag aattaaaagc ccaaatgaaa tggtaggtca   1200

gaaaccactt ggtgagatta caacagtgct aggttcccat ttgatttaca aaaagcgaat   1260

cagtaatcct ttccagggtt tgtctcaccg aggaagcaca atatccaaag ggcacaaaat   1320

tcagaagacg agtgatctga aacccagcca gactggacca aaggaaaagc ctttccaaaa   1380

gcctaggtcc ttggattcct caagaatctt tgatggtaaa gccaaagagc catatgctga   1440

acaacctaat gataaaatgg aagcagaatc catttacata aatgacccta ctgtcaaacc   1500

catcaatgat gacttcagag gtcacctctt cagtcaccct caacagagca tgttgcaaaa   1560

tgatggtaaa tgctgtccct ttatggaaag catgttgaga tatgaagtgt atggtggaga   1620

aaatgaggta attcctgaag tcttgaggaa aagtcattcc cactttgaca aattagggga   1680

gaccaaacag actccgcata gtctgccatc acgaggtgcc tccttttcag accgaacacc   1740

ctctgcttgt agattagtgg ataacacaat acaccagttt caaaatcttg gccttttgga   1800

ttacccagtt ggcgtgaacc ctttaagaca agctgcaaga caagacaaag actcagaaga   1860

attattgaga aaaggatttg tccaggatgc agagactaca agcctagaaa atgaacagct   1920

ttctaacgat gaccaggcct tgtatcagaa tgaagtggaa gatgatgatg gtgcctgtag   1980

ttcattatat ctagaggagg atgacatttc tgagaatgac gacttacgtc aaatgctgcc   2040

tggccacagt cagtattcct tcacaggtgg aagccaggga aatcatttag gaaaacaaaa   2100

agtgattgag agatctctga ccgagtacaa cagcacaatg gagagggttg agtctcaggt   2160

gcttaaaaga aatgaatgct acaaacccac tgggctgcat gctaccccag gtgaaagcca   2220

agaacctaac ctctctgctg aaagttgtgg cctaaattca ggggcccagt ttggttttaa   2280

ctacgaagaa gaacccagtg ttgctaaatg tgtacaggcc tcagcacctg ctgatgaaag   2340

aatctttgat tactatagcg caagaaaagc cagttttgaa gctgaagtca tacaagacac   2400

tattggtgac acaggaaaga agccagctag ctggagtcag agtcctcaga atcaggaaat   2460

gagaaaacat ttcccacaaa agttccaact tttcaacact tcacatatgc cagtgttggc   2520

tcaggatgtc caatatgaac acagtcactt ggaagggaca gaaaatcaca gcatggcagg   2580

agatagtgga atagattctc cacggacaca gagtctggga tctaataatt cagtcatttt   2640

ggatggacta aaaagaagac agaattttct gcaaaatgtc gaaggcacaa agagcagtca   2700

accactcaca tctaattcct tactaccgct aactccagtc ataaacgttt aattttcttt   2760

tggaaaccta cttttttctt tataaaaagg tagagcatta ttacagaatc tttcaatcat   2820

gtaagaattg agtatataag aattgtctaa aggcaagcat atctatacta ttaaccacat   2880

tacacatttt gttctaatta ctggcttttt ttcctctttt ggtgtcttaa ggctttttga   2940

agcttatttt actgtgagtt tattgggagt atatagatta ttttcgatta aaaagtggaa   3000

ttattggtcc ccttccaatt gtaattatct tgaattttta tacattagtt tctcaaatat   3060

atagaatgcc aatttacttc ctgtagtgaa ttttttttta acctacacta atattgagtt   3120

ctaagttaag tggatctcac cagatttcaa cacaaaatca gaaaacagtg tgtgttgaag   3180

cagtgtctgt tgcaagaaaa cagtgtctgc tgcaagatat ctatgcaacc ctaggtcttt   3240

atcattacca agaaagagtt tacataaatg tgttggctac tctgcaacaa gaattccttt   3300

aatcattgct gcccaggggc ttctctttga ccagcttgga catgaacaaa tggttcccaa   3360

tgtgactgac aatgtcgaaa attcctgtgg caagaggcat ctggctgtac tactgttcct   3420

ctggttcctc cctacatttc aggccttctt tgagatggag tcttgctctg ttgcccaggc   3480

tggagtgcag tcgcacaatc tcggctcact gcaacctctg cctcccaggt tcatgccatt   3540

ctcctgcccc agcttcccga gtagctggga ttacaggcgc ctgccaccac acccggcaaa   3600

ttttttgtat ttttagtaga gacggggttt caccgtgtta gccaggatga tctcgatctc   3660

ctgacctcgt gatccacccg cctcggcctc ccaaagtgtt gggattacag gcatgagcca   3720

ccgcacctga cccaggcc                                                 3738


<210>  6953
<211>  879
<212>  PRT
<213>  Homo sapiens

<400>  6953

Met Asn Pro Ile Thr Gln Ser Gln Phe Val Pro Leu Gly Glu Val Leu 
1               5                   10                  15


Cys Cys Ala Ile Ser Asp Met Asn Thr Ala Gln Ile Val Val Thr Gln 
            20                  25                  30


Glu Ser Leu Leu Glu Arg Leu Met Lys His Tyr Pro Gly Ile Ala Ile 
        35                  40                  45


Pro Ser Glu Asp Ile Leu Tyr Thr Thr Leu Gly Thr Leu Ile Lys Glu 
    50                  55                  60


Arg Lys Ile Tyr His Thr Gly Glu Gly Tyr Phe Ile Val Thr Pro Gln 
65                  70                  75                  80


Thr Tyr Phe Ile Thr Asn Thr Thr Thr Gln Glu Asn Lys Arg Met Leu 
                85                  90                  95


Pro Ser Asp Glu Ser Arg Leu Met Pro Ala Ser Met Thr Tyr Leu Val 
            100                 105                 110


Ser Met Glu Ser Cys Ala Glu Ser Ala Gln Glu Asn Ala Ala Pro Ile 
        115                 120                 125


Ser His Cys Gln Ser Cys Gln Cys Phe Arg Asp Met His Thr Gln Asp 
    130                 135                 140


Val Gln Glu Ala Pro Val Ala Ala Glu Val Thr Arg Lys Ser His Arg 
145                 150                 155                 160


Gly Leu Gly Glu Ser Val Ser Trp Val Gln Asn Gly Ala Val Ser Val 
                165                 170                 175


Ser Ala Glu His His Ile Cys Glu Ser Thr Lys Pro Leu Pro Tyr Thr 
            180                 185                 190


Arg Asp Lys Glu Lys Gly Lys Lys Phe Gly Phe Ser Leu Leu Trp Arg 
        195                 200                 205


Ser Leu Ser Arg Lys Glu Lys Pro Lys Thr Glu His Ser Ser Phe Ser 
    210                 215                 220


Ala Gln Phe Pro Pro Glu Glu Trp Pro Val Arg Asp Glu Asp Asp Leu 
225                 230                 235                 240


Asp Asn Ile Pro Arg Asp Val Glu His Glu Ile Ile Lys Arg Ile Asn 
                245                 250                 255


Pro Ile Leu Thr Val Asp Asn Leu Ile Lys His Thr Val Leu Met Gln 
            260                 265                 270


Lys Tyr Glu Glu Gln Lys Lys Tyr Asn Ser Gln Gly Thr Ser Thr Asp 
        275                 280                 285


Met Leu Thr Ile Gly His Lys Tyr Pro Ser Lys Glu Gly Val Lys Lys 
    290                 295                 300


Arg Gln Gly Leu Ser Ala Lys Pro Gln Gly Gln Gly His Ser Arg Arg 
305                 310                 315                 320


Asp Arg His Lys Ala Arg Asn Gln Gly Ser Glu Phe Gln Pro Gly Ser 
                325                 330                 335


Ile Arg Leu Glu Lys His Pro Lys Leu Pro Ala Thr Gln Pro Ile Pro 
            340                 345                 350


Arg Ile Lys Ser Pro Asn Glu Met Val Gly Gln Lys Pro Leu Gly Glu 
        355                 360                 365


Ile Thr Thr Val Leu Gly Ser His Leu Ile Tyr Lys Lys Arg Ile Ser 
    370                 375                 380


Asn Pro Phe Gln Gly Leu Ser His Arg Gly Ser Thr Ile Ser Lys Gly 
385                 390                 395                 400


His Lys Ile Gln Lys Thr Ser Asp Leu Lys Pro Ser Gln Thr Gly Pro 
                405                 410                 415


Lys Glu Lys Pro Phe Gln Lys Pro Arg Ser Leu Asp Ser Ser Arg Ile 
            420                 425                 430


Phe Asp Gly Lys Ala Lys Glu Pro Tyr Ala Glu Gln Pro Asn Asp Lys 
        435                 440                 445


Met Glu Ala Glu Ser Ile Tyr Ile Asn Asp Pro Thr Val Lys Pro Ile 
    450                 455                 460


Asn Asp Asp Phe Arg Gly His Leu Phe Ser His Pro Gln Gln Ser Met 
465                 470                 475                 480


Leu Gln Asn Asp Gly Lys Cys Cys Pro Phe Met Glu Ser Met Leu Arg 
                485                 490                 495


Tyr Glu Val Tyr Gly Gly Glu Asn Glu Val Ile Pro Glu Val Leu Arg 
            500                 505                 510


Lys Ser His Ser His Phe Asp Lys Leu Gly Glu Thr Lys Gln Thr Pro 
        515                 520                 525


His Ser Leu Pro Ser Arg Gly Ala Ser Phe Ser Asp Arg Thr Pro Ser 
    530                 535                 540


Ala Cys Arg Leu Val Asp Asn Thr Ile His Gln Phe Gln Asn Leu Gly 
545                 550                 555                 560


Leu Leu Asp Tyr Pro Val Gly Val Asn Pro Leu Arg Gln Ala Ala Arg 
                565                 570                 575


Gln Asp Lys Asp Ser Glu Glu Leu Leu Arg Lys Gly Phe Val Gln Asp 
            580                 585                 590


Ala Glu Thr Thr Ser Leu Glu Asn Glu Gln Leu Ser Asn Asp Asp Gln 
        595                 600                 605


Ala Leu Tyr Gln Asn Glu Val Glu Asp Asp Asp Gly Ala Cys Ser Ser 
    610                 615                 620


Leu Tyr Leu Glu Glu Asp Asp Ile Ser Glu Asn Asp Asp Leu Arg Gln 
625                 630                 635                 640


Met Leu Pro Gly His Ser Gln Tyr Ser Phe Thr Gly Gly Ser Gln Gly 
                645                 650                 655


Asn His Leu Gly Lys Gln Lys Val Ile Glu Arg Ser Leu Thr Glu Tyr 
            660                 665                 670


Asn Ser Thr Met Glu Arg Val Glu Ser Gln Val Leu Lys Arg Asn Glu 
        675                 680                 685


Cys Tyr Lys Pro Thr Gly Leu His Ala Thr Pro Gly Glu Ser Gln Glu 
    690                 695                 700


Pro Asn Leu Ser Ala Glu Ser Cys Gly Leu Asn Ser Gly Ala Gln Phe 
705                 710                 715                 720


Gly Phe Asn Tyr Glu Glu Glu Pro Ser Val Ala Lys Cys Val Gln Ala 
                725                 730                 735


Ser Ala Pro Ala Asp Glu Arg Ile Phe Asp Tyr Tyr Ser Ala Arg Lys 
            740                 745                 750


Ala Ser Phe Glu Ala Glu Val Ile Gln Asp Thr Ile Gly Asp Thr Gly 
        755                 760                 765


Lys Lys Pro Ala Ser Trp Ser Gln Ser Pro Gln Asn Gln Glu Met Arg 
    770                 775                 780


Lys His Phe Pro Gln Lys Phe Gln Leu Phe Asn Thr Ser His Met Pro 
785                 790                 795                 800


Val Leu Ala Gln Asp Val Gln Tyr Glu His Ser His Leu Glu Gly Thr 
                805                 810                 815


Glu Asn His Ser Met Ala Gly Asp Ser Gly Ile Asp Ser Pro Arg Thr 
            820                 825                 830


Gln Ser Leu Gly Ser Asn Asn Ser Val Ile Leu Asp Gly Leu Lys Arg 
        835                 840                 845


Arg Gln Asn Phe Leu Gln Asn Val Glu Gly Thr Lys Ser Ser Gln Pro 
    850                 855                 860


Leu Thr Ser Asn Ser Leu Leu Pro Leu Thr Pro Val Ile Asn Val 
865                 870                 875


<210>  6954
<211>  611
<212>  DNA
<213>  Homo sapiens

<400>  6954
cttccttgac atactgatct ttacttcatt gtgggtttct gatttggcta ctagagatct     60

tgatgacaag ctacttatga ggcctgggtc cagtaccatc ctttcaactc gaaattggcc    120

aaatcgagct gtggagttta gtacatcatc tctgtcatac acagtgcagt ccaccaggag    180

acgcaatcca ccaccacgaa ctcttcatcc cgactcgctc tcctctccct caccgacgcc    240

cctgagtcga aataatctgc taccacctat tggcacagct gaagtggaac atgtgagcac    300

tgtggggcca caaagacaga tgaaacccca tggcgactct agtcgagctc aaagtgcggt    360

ggtggatgaa cctaactatc agcagccaca agaaaggctc cttttgcccg actttttccc    420

caggcccaac acaactcaat catttttggt agagtgacgt acttcctaga atggtcttga    480

tagttgggga aagaaaaggt ggggggaata atagtttggc agacttaaga ttttatctag    540

aggcttaacc cagaataaaa gttgagtttc caacaataaa aagtgttata aatacatttt    600

gttcaaattc t                                                         611


<210>  6955
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  6955

Met Arg Pro Gly Ser Ser Thr Ile Leu Ser Thr Arg Asn Trp Pro Asn 
1               5                   10                  15


Arg Ala Val Glu Phe Ser Thr Ser Ser Leu Ser Tyr Thr Val Gln Ser 
            20                  25                  30


Thr Arg Arg Arg Asn Pro Pro Pro Arg Thr Leu His Pro Asp Ser Leu 
        35                  40                  45


Ser Ser Pro Ser Pro Thr Pro Leu Ser Arg Asn Asn Leu Leu Pro Pro 
    50                  55                  60


Ile Gly Thr Ala Glu Val Glu His Val Ser Thr Val Gly Pro Gln Arg 
65                  70                  75                  80


Gln Met Lys Pro His Gly Asp Ser Ser Arg Ala Gln Ser Ala Val Val 
                85                  90                  95


Asp Glu Pro Asn Tyr Gln Gln Pro Gln Glu Arg Leu Leu Leu Pro Asp 
            100                 105                 110


Phe Phe Pro Arg Pro Asn Thr Thr Gln Ser Phe Leu Val Glu 
        115                 120                 125


<210>  6956
<211>  2519
<212>  DNA
<213>  Homo sapiens

<400>  6956
aaaaatatcc tcaaaggtat gagataataa ggccacagca gtgttttcaa tgcggcttcc     60

aagttaagca ttattatgtg gatgtagcta tatctatacc aacagagcta taaatgcatt    120

catttgggga tgagtagtct tgatgtataa ttaatctctc attccttctg acagtacttt    180

ttttcaaagt tgaaaagtaa gttgctttgt tacttctggg acatgaaagt atcattcagt    240

ttcaattact gtcttaagga taaggaatac tgcaagctgc tccagatcct actgaaggga    300

atgaaggttt aggaacttta cccgagaact atagttatta gggaaaacga taaccagaag    360

gtccagaact gtcaagaatt ccatcatcag ctgggaattt acaaatccaa atcagcagag    420

aagtgcaata ccagataggg acaaatgttt tattccagtt ctgtgggaga gaaaaggcca    480

gcttctgttg tgtacccaga gtatagagct tcaaaacaaa atcagaaaac actattttaa    540

aaactaattt tccaaaaatc ctgagatctc tacttgaaaa cataggtagc ctaaagcttt    600

ctgtgcacat taaactcatc tgcttcattt atctgatttc taatcaattt gctggtattg    660

ttataacttc atgctttcat accttcgtgt ttgttggtgg gatctgcagc ccagtggcac    720

ccgactcgct ctcctctccc tcaccgacgc ccctgagtcg aaataatctg ctaccaccta    780

ttggcacagc tgaagtggaa catgtgagca ctgtggggcc acaaagacag atggtatgtt    840

tctttcatat tgcctctcca tgtacttacc atacaaccta atgggcagta attctgcagg    900

atctgtgccc tgatcttgat ttatactgtg ttttgtcaaa agtacaaaca cagtgctaat    960

ttatgacgtg gaattggagc tgtttggcct gcacttacca tatctgccat ggtcgatagg   1020

gttttaacta cataccacat tacagatagt tttcactgtt tctgtaactt ttgtctcctc   1080

tgcagaaacc ccatggcgac tctagtcgag ctcaaagtgc ggtggtggat gaacctaact   1140

atcagcagcc acaagaaagg ctccttttgc ccgacttttt ccccaggccc aacacaactc   1200

aatcattttt gctggataca cagtatcgtc gctcatgtgc agttgagtat cctcatcagg   1260

cccgacctgg caggggatct gcaggtcctc agttacatgg gtctacaaaa tctcaaagcg   1320

gaggcagacc agtctctcga accaggcagg gaccataagg caaatgagaa gaatctatca   1380

ggctgcagga aacacgagat ttcatgaagc agtattcagt catcaagtga tgcagagctt   1440

gtatagaaga tcgactagaa atcatcttca tgaagagtga ttttggcaca agtgaccgaa   1500

gaacaaaaca ccatagcagc caaaaatgac atgagtgttg tttctatctc cagttactgt   1560

ctctttcagc agaaattaac ctatcccatt ggaaaggcaa gtttgtaccc aaagatgcaa   1620

cagtgaataa tacccaaatc actgctcatg ttatctctta acaatgatca gttcaatcat   1680

ataggatttg atgagctcac acatacacaa aaagcagcaa atcatcagtg acaatatcac   1740

tggcttcaga atacttcagc ctgtgttcat ttctggagag ttgtactcag ttttaagtca   1800

ttttgctgtt gaaaatctga cctcatcaaa tagatgtcat tcctaaaact ctctttagat   1860

gtcctaccct atcagcagat taaaatggaa ggggtgtgta actaaaaaca taaatgttaa   1920

gcattagtat aaagtaactt ctgtaataaa ttatatcgca tattttttca gataggacag   1980

ctcaacctta cgatgcctac ctgatgccag gtgatgctta ttttcttcct aaagtaggtt   2040

actggtcata tcttttttcc aaatattaaa tgcaccttgc cagatattct cctgcagctc   2100

taaggaaagg aaatcaattt aaaaataatt tgtagaatct actattgagc caccaaagta   2160

taattcccta aaagtttaag aaaccctggc aattaattca gcataaacat atcctataaa   2220

cagcaggaga ggttcagctt tctgatttta ctgtggacct tttcctaagg gcattcatga   2280

atgcagcaac agttttaact atggcttaca tttattttaa atttcactaa atacaaatct   2340

tgattgtcat gccagtttta gatcttatta attttcagaa tggataaatt caaataatca   2400

taaattacgg taacttttta ttataccaag gtgttctaat gccatcatat gaagacagat   2460

gcttcaaaca acctgcatta aattatattt ttaataaaat taaaatctat ttttaacct    2519


<210>  6957
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  6957

Met Val Asp Arg Val Leu Thr Thr Tyr His Ile Thr Asp Ser Phe His 
1               5                   10                  15


Cys Phe Cys Asn Phe Cys Leu Leu Cys Arg Asn Pro Met Ala Thr Leu 
            20                  25                  30


Val Glu Leu Lys Val Arg Trp Trp Met Asn Leu Thr Ile Ser Ser His 
        35                  40                  45


Lys Lys Gly Ser Phe Cys Pro Thr Phe Ser Pro Gly Pro Thr Gln Leu 
    50                  55                  60


Asn His Phe Cys Trp Ile His Ser Ile Val Ala His Val Gln Leu Ser 
65                  70                  75                  80


Ile Leu Ile Arg Pro Asp Leu Ala Gly Asp Leu Gln Val Leu Ser Tyr 
                85                  90                  95


Met Gly Leu Gln Asn Leu Lys Ala Glu Ala Asp Gln Ser Leu Glu Pro 
            100                 105                 110


Gly Arg Asp His Lys Ala Asn Glu Lys Asn Leu Ser Gly Cys Arg Lys 
        115                 120                 125


His Glu Ile Ser 
    130


<210>  6958
<211>  313
<212>  DNA
<213>  Homo sapiens

<400>  6958
acctattggc acagctgaag tggaacatgt gagcactgtg gggccacaaa gacagatgaa     60

accccatggc gactctagtc gagctcaaag tgcggtggtg gatgaaccta actatcagca    120

gccacaagaa aggctccttt tgcccgactt tttccccagg cccaacacaa ctcaatcatt    180

tttggtagag tgacgtactt cctagaatgg tcttgatagt tggggaaaga aaaggtgggg    240

ggaataatag tttggcagac ttaagatttt atctagaggc ttaacccaga ataaaagttg    300

agtttccaac aat                                                       313


<210>  6959
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  6959

Met Lys Pro His Gly Asp Ser Ser Arg Ala Gln Ser Ala Val Val Asp 
1               5                   10                  15


Glu Pro Asn Tyr Gln Gln Pro Gln Glu Arg Leu Leu Leu Pro Asp Phe 
            20                  25                  30


Phe Pro Arg Pro Asn Thr Thr Gln Ser Phe Leu Val Glu 
        35                  40                  45


<210>  6960
<211>  1480
<212>  DNA
<213>  Homo sapiens

<400>  6960
agctgaagtg gaacatgtga gcactgtggg gccacaaaga cagatgaaac cccatggcga     60

ctctagtcga gctcaaagtg cggtggtgga tgaacctaac tatcagcagc cacaagaaag    120

gctccttttg cccgactttt tccccaggcc caacacaact caatcatttt tgctggatac    180

acagtatcgt cgctcatgtg cagttgagta tcctcatcag gcccgacctg gcaggggatc    240

tgcaggtcct cagttacatg ggtctacaaa atctcaaagc ggaggcagac cagtctctcg    300

aaccaggcag ggaccataag gcaaatgaga agaatctatc aggctgcagg aaacacgaga    360

tttcatgaag cagtattcag tcatcaagtg atgcagagct tgtatagaag atcgactaga    420

aatcatcttc atgaagagtg attttggcac aagtgaccga agaacaaaac accatagcag    480

ccaaaaatga catgagtgtt gtttctatct ccagttactg tctctttcag cagaaattaa    540

cctatcccat tggaaaggca agtttgtacc caaagatgca acagtgaata atacccaaat    600

cactgctcat gttatctctt aacaatgatc agttcaatca tataggattt gatgagctca    660

cacatacaca aaaagcagca aatcatcagt gacaatatca ctggcttcag aatacttcag    720

cctgtgttca tttctggaga gttgtactca gttttaagtc attttgctgt tgaaaatctg    780

acctcatcaa atagatgtca ttcctaaaac tctctttaga tgtcctaccc tatcagcaga    840

ttaaaatgga aggggtgtgt aactaaaaac ataaatgtta agcattagta taaagtaact    900

tctgtaataa attatatcgc atattttttc agataggaca gctcaacctt acgatgccta    960

cctgatgcca ggtgatgctt attttcttcc taaagtaggt tactggtcat atcttttttc   1020

caaatattaa atgcaccttg ccagatattc tcctgcagct ctaaggaaag gaaatcaatt   1080

taaaaataat ttgtagaatc tactattgag ccaccaaagt ataattccct aaaagtttaa   1140

gaaaccctgg caattaattc agcataaaca tatcctataa acagcaggag aggttcagct   1200

ttctgatttt actgtggacc ttttcctaag ggcattcatg aatgcagcaa cagttttaac   1260

tatggcttac atttatttta aatttcacta aatacaaatc ttgattgtca tgccagtttt   1320

agatcttatt aattttcaga atggataaat tcaaataatc ataaattacg gtaacttttt   1380

attataccaa ggtgttctaa tgccatcata tgaagacaga tgcttcaaac aacctgcatt   1440

aaattatatt tttaataaaa ttaaaatcta tttttaacct                         1480


<210>  6961
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  6961

Met Ala Thr Leu Val Glu Leu Lys Val Arg Trp Trp Met Asn Leu Thr 
1               5                   10                  15


Ile Ser Ser His Lys Lys Gly Ser Phe Cys Pro Thr Phe Ser Pro Gly 
            20                  25                  30


Pro Thr Gln Leu Asn His Phe Cys Trp Ile His Ser Ile Val Ala His 
        35                  40                  45


Val Gln Leu Ser Ile Leu Ile Arg Pro Asp Leu Ala Gly Asp Leu Gln 
    50                  55                  60


Val Leu Ser Tyr Met Gly Leu Gln Asn Leu Lys Ala Glu Ala Asp Gln 
65                  70                  75                  80


Ser Leu Glu Pro Gly Arg Asp His Lys Ala Asn Glu Lys Asn Leu Ser 
                85                  90                  95


Gly Cys Arg Lys His Glu Ile Ser 
            100


<210>  6962
<211>  3511
<212>  DNA
<213>  Homo sapiens

<400>  6962
agctgaagtg gaacatgtga gcactgtggg gccacaaaga cagatgaaac cccatggcga     60

ctctagtcga gctcaaagtg cggtggtgga tgaacctaac tatcagcagc cacaagaaag    120

gctccttttg cccgactttt tccccaggcc caacacaact caatcatttt tgctggatac    180

acagtatcgt cgctcatgtg cagttgagta tcctcatcag gcccgacctg gcaggggatc    240

tgcaggtcct cagttacatg ggtctacaaa atctcaaagc ggaggcagac cagtctctcg    300

aaccaggcag ggaccataag gcaaatgaga agaatctatc aggctgcagg aaacacgaga    360

tttcatgaag cagtattcag tcatcaagtg atgcagagct tgtatagaag atcgactaga    420

aatcatcttc atgaagagtg attttggcac aagtgaccga agaacaaaac accatagcag    480

ccaaaaatga catgagtgtt gtttctatct ccagttactg tctctttcag cagaaattaa    540

cctatcccat tggaaaggca agtttgtacc caaagatgca acagtgaata atacccaaat    600

cactgctcat gttatctctt aacaatgatc agttcaatca tataggattt gatgagctca    660

cacatacaca aaaagcagca aatcatcagt gacaatatca ctggcttcag aatacttcag    720

cctgtgttca tttctggaga gttgtactca gttttaagtc attttgctgt tgaaaatctg    780

acctcatcaa atagatgtca ttcctaaaac tctctttaga tgtcctaccc tatcagcaga    840

ttaaaatgga aggggtgtgt aactaaaaac ataaatgtta agcattagta taaagtaact    900

tctgtaataa attatatcgc atattttttc agataggaca gctcaacctt acgatgccta    960

cctgatgcca ggtgatgctt attttcttcc taaagtaggt tactggtcat atcttttttc   1020

caaatattaa atgcaccttg ccagatattc tcctgcagct ctaaggaaag gaaatcaatt   1080

taaaaataat ttgtagaatc tactattgag ccaccaaagt ataattccct aaaagtttaa   1140

gaaaccctgg caattaattc agcataaaca tatcctataa acagcaggag aggttcagct   1200

ttctgatttt actgtggacc ttttcctaag ggcattcatg aatgcagcaa cagttttaac   1260

tatggcttac atttatttta aatttcacta aatacaaatc ttgattgtca tgccagtttt   1320

agatcttatt aattttcaga atggataaat tcaaataatc ataaattacg gtaacttttt   1380

attataccaa ggtgttctaa tgccatcata tgaagacaga tgcttcaaac aacctgcatt   1440

aaattatatt tttaataaaa ttaaaatcta tttttaacct atttgtagtc acaaaccgaa   1500

aacgtgtcgt ctttacctta gagctaaagg cttactttat gcatacggta tatttaatag   1560

tctacaaatc aaagatttaa acagtccctt aaaaattcca tatattctca taccaactca   1620

tctacataga aatgaaaatc tctattgttc tcacaaacca ttaccatgag ttcactataa   1680

caactggatc aatatggctt gcctttcaaa gttaaagaat cagaaagggg cctgtaagaa   1740

gtcatttagc ccaattccct caccctgtgt gttttccctc aaagccagtg caattttttt   1800

ttaaccaaaa aactggacat gtttaataca tacagtttga caaatttgga tttcactctt   1860

tgttttgatg tagtaactct tttataaaag ggaacagatt cagacaagct cagtggccca   1920

actgaagaca ttcagcaatt aatggcagga cttcagtaat cagtggcagg actacaacat   1980

acatctcttc atgctaggga aaccaggctc tctattataa agctgaccag ggctattgtt   2040

ttcccctttt ctctcatcct aaacaccatt catatttttc ctaggtcaca ttttagtggg   2100

atcatttaca aagcccccag aacttaatca tcatgtttta ccttttttat tgaattatat   2160

acacctctta caaaaatgct tgaagtaatt taacacctgt acatcagtac aaaacctggc   2220

tgagtaaaat gaagagagga tctattcaag atcattaaga ccaaatgtaa actgggaagt   2280

atgtggaaga tagctgtcca gcaagtgtct ggaaggtgtt ctagctgggt agagagccta   2340

ttctaacaga cacgcacatc gcagaaagca gcatgaacag aaccacatcc tagataagag   2400

ttctgtgtac agaagatcca tggaggcaag tgctgtcagg aaggacactg cctccctcca   2460

ccctcccaaa tgtcaccacc aagttccttc aggtgagacc tcacacaatg tcaagtgctt   2520

tctaggaaat actaagatca ggttgagaga ttctgcttgg tctagtcaat ctgaaaaatt   2580

caggctggaa agacaccttt tctcaagagc tgaattgact tttgccttca aatcctgcct   2640

gcaccttgcc tacgatggca tcaatttaca cctaaggacc tttgaagaga aaaattccat   2700

tatttctttt ctttcttgag agcagatttt ttccctcctc ctttggaaga tttgcagtac   2760

tttgcttcca tctgagccag aaaattgtcc atttcctttt gccgatcctt ttgtctgctc   2820

tgtttgagaa gttaaaacac aagctttcac aacattatcc atagacagaa agtacctagt   2880

ggttgccagg ggctggaaaa gtggaataac tactaatggg tatggagttt ttttggaatg   2940

gtgaaaatgt cctacaattg gtgttaataa ttgtaaaact ttgtaaatac acttaaaacc   3000

accaaattgt acactttaaa aggacaaata gaaggtatgc ggttatgtct taaaagaaga   3060

aaacaaaata caacattcca aagaaaatat tagcagtagg aatcagatca ttaaagatgt   3120

ggcaacaaac tgccaagttt acctgaatgg ctgccttcag gctatccacg ccttcatcaa   3180

gccccaactc ctttctgctc atttctgctt ctttggcctc ttcctgagcc tgaaacagga   3240

actcacatga gactcagggc caccaggaaa tgcttaaaat acatactctt tcccaaaagc   3300

aaatctataa ttctgtttca attttatgaa tatatgaata gacaaaatga atcgaattac   3360

ataactatgt cattcattaa atggcaacaa tgctgacagc aagcagtaga tcctctgatt   3420

ccaattacca tttgtttttt acccaattct atttgctaga ggtagtaagt actctggcac   3480

tcataaatca catgatgata aaaaggaaca t                                  3511


<210>  6963
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  6963

Met Ala Thr Leu Val Glu Leu Lys Val Arg Trp Trp Met Asn Leu Thr 
1               5                   10                  15


Ile Ser Ser His Lys Lys Gly Ser Phe Cys Pro Thr Phe Ser Pro Gly 
            20                  25                  30


Pro Thr Gln Leu Asn His Phe Cys Trp Ile His Ser Ile Val Ala His 
        35                  40                  45


Val Gln Leu Ser Ile Leu Ile Arg Pro Asp Leu Ala Gly Asp Leu Gln 
    50                  55                  60


Val Leu Ser Tyr Met Gly Leu Gln Asn Leu Lys Ala Glu Ala Asp Gln 
65                  70                  75                  80


Ser Leu Glu Pro Gly Arg Asp His Lys Ala Asn Glu Lys Asn Leu Ser 
                85                  90                  95


Gly Cys Arg Lys His Glu Ile Ser 
            100


<210>  6964
<211>  3663
<212>  DNA
<213>  Homo sapiens

<400>  6964
gtaattctgc aggatctgtg ccctgatctt gatttatact gtgttttgtc aaaagtacaa     60

acacagtgct aatttatgac gtggaattgg agctgtttgg cctgcactta ccatatctgc    120

catggtcgat agggttttaa ctacatacca cattacagat agttttcact gtttctgtaa    180

cttttgtctc ctctgcagaa accccatggc gactctagtc gagctcaaag tgcggtggtg    240

gatgaaccta actatcagca gccacaagaa aggctccttt tgcccgactt tttccccagg    300

cccaacacaa ctcaatcatt tttgctggat acacagtatc gtcgctcatg tgcagttgag    360

tatcctcatc aggcccgacc tggcagggga tctgcaggtc ctcagttaca tgggtctaca    420

aaatctcaaa gcggaggcag accagtctct cgaaccaggc agggaccata aggcaaatga    480

gaagaatcta tcaggctgca ggaaacacga gatttcatga agcagtattc agtcatcaag    540

tgatgcagag cttgtataga agatcgacta gaaatcatct tcatgaagag tgattttggc    600

acaagtgacc gaagaacaaa acaccatagc agccaaaaat gacatgagtg ttgtttctat    660

ctccagttac tgtctctttc agcagaaatt aacctatccc attggaaagg caagtttgta    720

cccaaagatg caacagtgaa taatacccaa atcactgctc atgttatctc ttaacaatga    780

tcagttcaat catataggat ttgatgagct cacacataca caaaaagcag caaatcatca    840

gtgacaatat cactggcttc agaatacttc agcctgtgtt catttctgga gagttgtact    900

cagttttaag tcattttgct gttgaaaatc tgacctcatc aaatagatgt cattcctaaa    960

actctcttta gatgtcctac cctatcagca gattaaaatg gaaggggtgt gtaactaaaa   1020

acataaatgt taagcattag tataaagtaa cttctgtaat aaattatatc gcatattttt   1080

tcagatagga cagctcaacc ttacgatgcc tacctgatgc caggtgatgc ttattttctt   1140

cctaaagtag gttactggtc atatcttttt tccaaatatt aaatgcacct tgccagatat   1200

tctcctgcag ctctaaggaa aggaaatcaa tttaaaaata atttgtagaa tctactattg   1260

agccaccaaa gtataattcc ctaaaagttt aagaaaccct ggcaattaat tcagcataaa   1320

catatcctat aaacagcagg agaggttcag ctttctgatt ttactgtgga ccttttccta   1380

agggcattca tgaatgcagc aacagtttta actatggctt acatttattt taaatttcac   1440

taaatacaaa tcttgattgt catgccagtt ttagatctta ttaattttca gaatggataa   1500

attcaaataa tcataaatta cggtaacttt ttattatacc aaggtgttct aatgccatca   1560

tatgaagaca gatgcttcaa acaacctgca ttaaattata tttttaataa aattaaaatc   1620

tatttttaac ctatttgtag tcacaaaccg aaaacgtgtc gtctttacct tagagctaaa   1680

ggcttacttt atgcatacgg tatatttaat agtctacaaa tcaaagattt aaacagtccc   1740

ttaaaaattc catatattct cataccaact catctacata gaaatgaaaa tctctattgt   1800

tctcacaaac cattaccatg agttcactat aacaactgga tcaatatggc ttgcctttca   1860

aagttaaaga atcagaaagg ggcctgtaag aagtcattta gcccaattcc ctcaccctgt   1920

gtgttttccc tcaaagccag tgcaattttt ttttaaccaa aaaactggac atgtttaata   1980

catacagttt gacaaatttg gatttcactc tttgttttga tgtagtaact cttttataaa   2040

agggaacaga ttcagacaag ctcagtggcc caactgaaga cattcagcaa ttaatggcag   2100

gacttcagta atcagtggca ggactacaac atacatctct tcatgctagg gaaaccaggc   2160

tctctattat aaagctgacc agggctattg ttttcccctt ttctctcatc ctaaacacca   2220

ttcatatttt tcctaggtca cattttagtg ggatcattta caaagccccc agaacttaat   2280

catcatgttt tacctttttt attgaattat atacacctct tacaaaaatg cttgaagtaa   2340

tttaacacct gtacatcagt acaaaacctg gctgagtaaa atgaagagag gatctattca   2400

agatcattaa gaccaaatgt aaactgggaa gtatgtggaa gatagctgtc cagcaagtgt   2460

ctggaaggtg ttctagctgg gtagagagcc tattctaaca gacacgcaca tcgcagaaag   2520

cagcatgaac agaaccacat cctagataag agttctgtgt acagaagatc catggaggca   2580

agtgctgtca ggaaggacac tgcctccctc caccctccca aatgtcacca ccaagttcct   2640

tcaggtgaga cctcacacaa tgtcaagtgc tttctaggaa atactaagat caggttgaga   2700

gattctgctt ggtctagtca atctgaaaaa ttcaggctgg aaagacacct tttctcaaga   2760

gctgaattga cttttgcctt caaatcctgc ctgcaccttg cctacgatgg catcaattta   2820

cacctaagga cctttgaaga gaaaaattcc attatttctt ttctttcttg agagcagatt   2880

ttttccctcc tcctttggaa gatttgcagt actttgcttc catctgagcc agaaaattgt   2940

ccatttcctt ttgccgatcc ttttgtctgc tctgtttgag aagttaaaac acaagctttc   3000

acaacattat ccatagacag aaagtaccta gtggttgcca ggggctggaa aagtggaata   3060

actactaatg ggtatggagt ttttttggaa tggtgaaaat gtcctacaat tggtgttaat   3120

aattgtaaaa ctttgtaaat acacttaaaa ccaccaaatt gtacacttta aaaggacaaa   3180

tagaaggtat gcggttatgt cttaaaagaa gaaaacaaaa tacaacattc caaagaaaat   3240

attagcagta ggaatcagat cattaaagat gtggcaacaa actgccaagt ttacctgaat   3300

ggctgccttc aggctatcca cgccttcatc aagccccaac tcctttctgc tcatttctgc   3360

ttctttggcc tcttcctgag cctgaaacag gaactcacat gagactcagg gccaccagga   3420

aatgcttaaa atacatactc tttcccaaaa gcaaatctat aattctgttt caattttatg   3480

aatatatgaa tagacaaaat gaatcgaatt acataactat gtcattcatt aaatggcaac   3540

aatgctgaca gcaagcagta gatcctctga ttccaattac catttgtttt ttacccaatt   3600

ctatttgcta gaggtagtaa gtactctggc actcataaat cacatgatga taaaaaggaa   3660

cat                                                                 3663


<210>  6965
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  6965

Met Val Asp Arg Val Leu Thr Thr Tyr His Ile Thr Asp Ser Phe His 
1               5                   10                  15


Cys Phe Cys Asn Phe Cys Leu Leu Cys Arg Asn Pro Met Ala Thr Leu 
            20                  25                  30


Val Glu Leu Lys Val Arg Trp Trp Met Asn Leu Thr Ile Ser Ser His 
        35                  40                  45


Lys Lys Gly Ser Phe Cys Pro Thr Phe Ser Pro Gly Pro Thr Gln Leu 
    50                  55                  60


Asn His Phe Cys Trp Ile His Ser Ile Val Ala His Val Gln Leu Ser 
65                  70                  75                  80


Ile Leu Ile Arg Pro Asp Leu Ala Gly Asp Leu Gln Val Leu Ser Tyr 
                85                  90                  95


Met Gly Leu Gln Asn Leu Lys Ala Glu Ala Asp Gln Ser Leu Glu Pro 
            100                 105                 110


Gly Arg Asp His Lys Ala Asn Glu Lys Asn Leu Ser Gly Cys Arg Lys 
        115                 120                 125


His Glu Ile Ser 
    130


<210>  6966
<211>  5411
<212>  DNA
<213>  Homo sapiens

<400>  6966
cttattcttg tacttttctt tcttgctggt aattttatgg agcaggttaa gaaggctgct     60

ctgtgttagg ataaactgta taccaataat gttgacaacc tgtaatgagt gttgcatttt    120

acttcttgta tcttttcctt cctaccttga tgccagtaat ctataaggga tctttatagt    180

ttgaatgtat ttgaataact tcagtatact ttagttctac ttttttattt gactcacaac    240

cattcttagg tctcaagtat tcccatgtgt tttaaaagcc tgaagtcagt gagatgaaat    300

tcaacatcaa gaatttgaag taacttgtaa ggaaaaataa tataaagata ccattggggc    360

agtggctcac acctgtaatc tcagcacttt gggaggctga ggtggaagga tcacttgaag    420

ccagagtttg agaccagcct gtgcaacaca gcaagacccc gtctctacaa aaacttaaaa    480

aattagctgg ctgtggtgtt gctcacccat agttccagct actcgggaag ctgaggcagt    540

aagatcactt gagcccagga ggccgatgct gcagtgaact gtgattgttc cactacagtc    600

cagcctgggt gacagagaaa agaaaaagaa aacattacat aatttggcta gagcataata    660

atttgatttt ctggtttttg aaaatttgag ttgcaataaa aggatatttc agtgtgcgat    720

ttcaattttc cgtagcaaat gtatatatag aaaaatgtta aaatagatgt atttgaatac    780

cttaaaaaat acaagaaact ggaagaaaga taatattgca aagcatctac atatatccta    840

ggccttttgt gtacaaggtt atttgtgaca attgtaaggt attatgaagg caggtaggat    900

tatctccgtt ttacagatag ggaagctgag gcctagaggt ggaaacttgc ccagtgatgt    960

aagattcatc tcccggttat gccctcctgg aaagcccttc ccaacatatt atgttgtcca   1020

tagagggaaa aatgagcaaa gacagatggc ttaactctgg tgtgtgacta agatatagga   1080

aatttataga ggaggttcta tcaatgtgcc gacttacttt gtgttttatg ttctgagaac   1140

gattaccagc catctcaaat tctgtggttg tcaaagctcc cctggggttg ttgctggttg   1200

gcccccactt gctttgagac tttgatgcca gggcaggttg agaggaactg acttcagctg   1260

agtttgatct tggatctggg aaagagaaat gctttgaaaa tcacggcaac tctgggaagt   1320

ttaaaagata ttaatgtatc ctggagagtt tgaggctttg cagaaactta ttggcagagc   1380

agaatgattc tgaaaaatgc tacatcagtg aggggatatt tgataaggta ttttctgcca   1440

actcgggtat tcacttagca ttgtttatcc tttaagatat gtatacacat acttcctctg   1500

tgagtttacc ctactaacaa agttttatcc ccagcctcaa ccttgctttg ggtctccagg   1560

cccaagtttc tcaccatctc ttggatgatt gctccagccc actctgctgc cacctgggat   1620

ccaacatgtt caaacccagc tgtgaacttc acagagtatt aaaagaaaga gcctttgctt   1680

cagcagttta tgttattaag acggaggctt gggtcatgtt atctctctcc accaatgtgt   1740

aaggtgaaag tcctattagg taagagtttt tggaagaccc gtgttttgtg ctttttgggt   1800

ttcagtatag ggttttttcc tacagggcta gagggaaagt accccagcat ttccaaccag   1860

tggggtgcaa aattatttgg gtctacagct ttacctattc ctttcaagaa catttttgaa   1920

aaaacacatc tgttaagttg aaccatgtgt aactgctgaa tgctgatgtt tggccgtttt   1980

ctacttaaaa aaataggcca gcagtttgta aattcaagct aatatatgaa ctttttgaaa   2040

aagttgttct tggacactaa aaggtaagac ggacgccaga tttccagagc aaggggagga   2100

gagacccgag caacatcact tccctgaaga cctagctcct gcgcgcggcc ggggactgtg   2160

actccacatg ccggcgttac ttacccgggc ccgcgcctga ctcgccacac ctcattttgc   2220

ggccgccgta aagcgcggat gcgcggcgtg gccacgcccc ttcagtgctt gtgacgcagg   2280

cgccctgggc tttttgggcg cgaaaaagaa gcagtcctgg gttgtacccg gcgcagctgg   2340

gagcggctgc ttcctccggg gtcgtatctc cgcccggcat ggggctgctg gacctttgcg   2400

aggaagtgtt cggcaccgcc gacctttacc gggtgctggg cgtgcgacgc gaggcctccg   2460

acggcgaggt ccgacgaggc taccacaagg tgtccctgca ggtacacccg gaccgggtgg   2520

gtgagggcga caaggaggac gccacccgcc gcttccagat cctgggaaaa gtctattccg   2580

ttctcagtga cagagaacag agagcagtgt acgatgagca gggaacagtg gacgaggact   2640

ctcctgtgct cacccaagac cgagactggg aggcgtattg gcggctactc tttaaaaaga   2700

tatctttaga ggacattcaa gcttttgaaa agacatacaa aggttcggaa gaagagctgg   2760

ctgatattaa gcaggcctat ctggacttca agggtgacat ggatcagatc atggagtctg   2820

tgctttgcgt gcagtacaca gaggaaccca ggataaggaa tatcattcag caagctattg   2880

acgccggaga ggtcccatcc tataatgcct ttgtcaaaga atcgaaacaa aagatgaatg   2940

caaggaaaag gagggctcag gaagaggcca aagaagcaga aatgagcaga aaggagttgg   3000

ggcttgatga aggcgtggat agcctgaagg cagccattca gagcagacaa aaggatcggc   3060

aaaaggaaat ggacaatttt ctggctcaga tggaagcaaa gtactgcaaa tcttccaaag   3120

gaggagggaa aaaatctgct ctcaagaaag aaaagaaata atggaatttt tctcttcaaa   3180

ggtccttagg tgtaaattga tgccatcgta ggcaaggtgc aggcaggatt tgaaggcaaa   3240

agtcaattca gctcttgaga aaaggtgtct ttccagcctg aatttttcag attgactaga   3300

ccaagcagaa tctctcaacc tgatcttagt atttcctaga aagcacttga cattgtgtga   3360

ggtctcacct gaaggaactt ggtggtgaca tttgggaggg tggagggagg cagtgtcctt   3420

cctgacagca cttgcctcca tggatcttct gtacacagaa ctcttatcta ggatgtggtt   3480

ctgttcatgc tgctttctgc gatgtgcgtg tctgttagaa taggctctct acccagctag   3540

aacaccttcc agacacttgc tggacagcta tcttccacat acttcccagt ttacatttgg   3600

tcttaatgat cttgaataga tcctctcttc attttactca gccaggtttt gtactgatgt   3660

acaggtgtta aattacttca agcatttttg taagaggtgt atataattca ataaaaaagg   3720

taaaacatga tgattaagtt ctgggggctt tgtaaatgat cccactaaaa tgtgacctag   3780

gaaaaatatg aatggtgttt aggatgagag aaaaggggaa aacaatagcc ctggtcagct   3840

ttataataga gagcctggtt tccctagcat gaagagatgt atgttgtagt cctgccactg   3900

attactgaag tcctgccatt aattgctgaa tgtcttcagt tgggccactg agcttgtctg   3960

aatctgttcc cttttataaa agagttacta catcaaaaca aagagtgaaa tccaaatttg   4020

tcaaactgta tgtattaaac atgtccagtt ttttggttaa aaaaaaattg cactggcttt   4080

gagggaaaac acacagggtg agggaattgg gctaaatgac ttcttacagg cccctttctg   4140

attctttaac tttgaaaggc aagccatatt gatccagttg ttatagtgaa ctcatggtaa   4200

tggtttgtga gaacaataga gattttcatt tctatgtaga tgagttggta tgagaatata   4260

tggaattttt aagggactgt ttaaatcttt gatttgtaga ctattaaata taccgtatgc   4320

ataaagtaag cctttagctc taaggtaaag acgacacgtt ttcggtttgt gactacaaat   4380

aggttaaaaa tagattttaa ttttattaaa aatataattt aatgcaggtt gtttgaagca   4440

tctgtcttca tatgatggca ttagaacacc ttggtataat aaaaagttac cgtaatttat   4500

gattatttga atttatccat tctgaaaatt aataagatct aaaactggca tgacaatcaa   4560

gatttgtatt tagtgaaatt taaaataaat gtaagccata gttaaaactg ttgctgcatt   4620

catgaatgcc cttaggaaaa ggtccacagt aaaatcagaa agctgaacct ctcctgctgt   4680

ttataggata tgtttatgct gaattaattg ccagggtttc ttaaactttt agggaattat   4740

actttggtgg ctcaatagta gattctacaa attattttta aattgatttc ctttccttag   4800

agctgcagga gaatatctgg caaggtgcat ttaatatttg gaaaaaagat atgaccagta   4860

acctacttta ggaagaaaat aagcatcacc tggcatcagg taggcatcgt aaggttgagc   4920

tgtcctatct gaaaaaatat gcgatataat ttattacaga agttacttta tactaatgct   4980

taacatttat gtttttagtt acacacccct tccattttaa tctgctgata gggtaggaca   5040

tctaaagaga gttttaggaa tgacatctat ttgatgaggt cagattttca acagcaaaat   5100

gacttaaaac tgagtacaac tctccagaaa tgaacacagg ctgaagtatt ctgaagccag   5160

tgatattgtc actgatgatt tgctgctttt tgtgtatgtg tgagctcatc aaatcctata   5220

tgattgaact gatcattgtt aagagataac atgagcagtg atttgggtat tattcactgt   5280

tgcatctttg ggtacaaact tgcctttcca atgggatagg ttaatttctg ctgaaagaga   5340

cagtaactgg agatagaaac aacactcatg tcatttttgg ctgctatggt gttttgttct   5400

tcggtcactt g                                                        5411


<210>  6967
<211>  260
<212>  PRT
<213>  Homo sapiens

<400>  6967

Met Gly Leu Leu Asp Leu Cys Glu Glu Val Phe Gly Thr Ala Asp Leu 
1               5                   10                  15


Tyr Arg Val Leu Gly Val Arg Arg Glu Ala Ser Asp Gly Glu Val Arg 
            20                  25                  30


Arg Gly Tyr His Lys Val Ser Leu Gln Val His Pro Asp Arg Val Gly 
        35                  40                  45


Glu Gly Asp Lys Glu Asp Ala Thr Arg Arg Phe Gln Ile Leu Gly Lys 
    50                  55                  60


Val Tyr Ser Val Leu Ser Asp Arg Glu Gln Arg Ala Val Tyr Asp Glu 
65                  70                  75                  80


Gln Gly Thr Val Asp Glu Asp Ser Pro Val Leu Thr Gln Asp Arg Asp 
                85                  90                  95


Trp Glu Ala Tyr Trp Arg Leu Leu Phe Lys Lys Ile Ser Leu Glu Asp 
            100                 105                 110


Ile Gln Ala Phe Glu Lys Thr Tyr Lys Gly Ser Glu Glu Glu Leu Ala 
        115                 120                 125


Asp Ile Lys Gln Ala Tyr Leu Asp Phe Lys Gly Asp Met Asp Gln Ile 
    130                 135                 140


Met Glu Ser Val Leu Cys Val Gln Tyr Thr Glu Glu Pro Arg Ile Arg 
145                 150                 155                 160


Asn Ile Ile Gln Gln Ala Ile Asp Ala Gly Glu Val Pro Ser Tyr Asn 
                165                 170                 175


Ala Phe Val Lys Glu Ser Lys Gln Lys Met Asn Ala Arg Lys Arg Arg 
            180                 185                 190


Ala Gln Glu Glu Ala Lys Glu Ala Glu Met Ser Arg Lys Glu Leu Gly 
        195                 200                 205


Leu Asp Glu Gly Val Asp Ser Leu Lys Ala Ala Ile Gln Ser Arg Gln 
    210                 215                 220


Lys Asp Arg Gln Lys Glu Met Asp Asn Phe Leu Ala Gln Met Glu Ala 
225                 230                 235                 240


Lys Tyr Cys Lys Ser Ser Lys Gly Gly Gly Lys Lys Ser Ala Leu Lys 
                245                 250                 255


Lys Glu Lys Lys 
            260


<210>  6968
<211>  4603
<212>  DNA
<213>  Homo sapiens

<400>  6968
cttattcttg tacttttctt tcttgctggt aattttatgg agcaggttaa gaaggctgct     60

ctgtgttagg ataaactgta taccaataat gttgacaacc tgtaatgagt gttgcatttt    120

acttcttgta tcttttcctt cctaccttga tgccagtaat ctataaggga tctttatagt    180

ttgaatgtat ttgaataact tcagtatact ttagttctac ttttttattt gactcacaac    240

cattcttagg tctcaagtat tcccatgtgt tttaaaagcc tgaagtcagt gagatgaaat    300

tcaacatcaa gaatttgaag taacttgtaa ggaaaaataa tataaagata ccattggggc    360

agtggctcac acctgtaatc tcagcacttt gggaggctga ggtggaagga tcacttgaag    420

ccagagtttg agaccagcct gtgcaacaca gcaagacccc gtctctacaa aaacttaaaa    480

aattagctgg ctgtggtgtt gctcacccat agttccagct actcgggaag ctgaggcagt    540

aagatcactt gagcccagga ggccgatgct gcagtgaact gtgattgttc cactacagtc    600

cagcctgggt gacagagaaa agaaaaagaa aacattacat aatttggcta gagcataata    660

atttgatttt ctggtttttg aaaatttgag ttgcaataaa aggatatttc agtgtgcgat    720

ttcaattttc cgtagcaaat gtatatatag aaaaatgtta aaatagatgt atttgaatac    780

cttaaaaaat acaagaaact ggaagaaaga taatattgca aagcatctac atatatccta    840

ggccttttgt gtacaaggtt atttgtgaca attgtaaggt attatgaagg caggtaggat    900

tatctccgtt ttacagatag ggaagctgag gcctagaggt ggaaacttgc ccagtgatgt    960

aagattcatc tcccggttat gccctcctgg aaagcccttc ccaacatatt atgttgtcca   1020

tagagggaaa aatgagcaaa gacagatggc ttaactctgg tgtgtgacta agatatagga   1080

aatttataga ggaggttcta tcaatgtgcc gacttacttt gtgttttatg ttctgagaac   1140

gattaccagc catctcaaat tctgtggttg tcaaagctcc cctggggttg ttgctggttg   1200

gcccccactt gctttgagac tttgatgcca gggcaggttg agaggaactg acttcagctg   1260

agtttgatct tggatctggg aaagagaaat gctttgaaaa tcacggcaac tctgggaagt   1320

ttaaaagata ttaatgtatc ctggagagtt tgaggctttg cagaaactta ttggcagagc   1380

agaatgattc tgaaaaatgc tacatcagtg aggggatatt tgataaggta ttttctgcca   1440

actcgggtat tcacttagca ttgtttatcc tttaagatat gtatacacat acttcctctg   1500

tgagtttacc ctactaacaa agttttatcc ccagcctcaa ccttgctttg ggtctccagg   1560

cccaagtttc tcaccatctc ttggatgatt gctccagccc actctgctgc cacctgggat   1620

ccaacatgtt caaacccagc tgtgaacttc acagagtatt aaaagaaaga gcctttgctt   1680

cagcagttta tgttattaag acggaggctt gggtcatgtt atctctctcc accaatgtgt   1740

aaggtgaaag tcctattagg taagagtttt tggaagaccc gtgttttgtg ctttttgggt   1800

ttcagtatag ggttttttcc tacagggcta gagggaaagt accccagcat ttccaaccag   1860

tggggtgcaa aattatttgg gtctacagct ttacctattc ctttcaagaa catttttgaa   1920

aaaacacatc tgttaagttg aaccatgtgt aactgctgaa tgctgatgtt tggccgtttt   1980

ctacttaaaa aaataggcca gcagtttgta aattcaagct aatatatgaa ctttttgaaa   2040

aagttgttct tggacactaa aaggtaagac ggacgccaga tttccagagc aaggggagga   2100

gagacccgag caacatcact tccctgaaga cctagctcct gcgcgcggcc ggggactgtg   2160

actccacatg ccggcgttac ttacccgggc ccgcgcctga ctcgccacac ctcattttgc   2220

ggccgccgta aagcgcggat gcgcggcgtg gccacgcccc ttcagtgctt gtgacgcagg   2280

cgccctgggc tttttgggcg cgaaaaagaa gcagtcctgg gttgtacccg gcgcagctgg   2340

gagcggctgc ttcctccggg gtcgtatctc cgcccggcat ggggctgctg gacctttgcg   2400

aggaagtgtt cggcaccgcc gacctttacc gggtgctggg cgtgcgacgc gaggcctccg   2460

acggcgaggt ccgacgaggc taccacaagg tgtccctgca ggtacacccg gaccgggtgg   2520

gtgagggcga caaggaggac gccacccgcc gcttccagat cctgggaaaa gtctattccg   2580

ttctcagtga cagagaacag agagcagtgt acgatgagca gggaacagtg gacgaggact   2640

ctcctgtgct cacccaagac cgagactggg aggcgtattg gcggctactc tttaaaaaga   2700

tatctttaga ggacattcaa gcttttgaaa agacatacaa aggttcggaa gaagagctgg   2760

ctgatattaa gcaggcctat ctggacttca agggtgacat ggatcagatc atggagtctg   2820

tgctttgcgt gcagtacaca gaggaaccca ggataaggaa tatcattcag caagctattg   2880

acgccggaga ggtcccatcc tataatgcct ttgtcaaaga atcgaaacaa aagatgaatg   2940

caaggaaaag gagggctcag gaagaggcca aagaagcaga aatgagcaga aaggagttgg   3000

ggcttgatga aggcgtggat agcctgaagg cagccattca gagcagacaa aaggatcggc   3060

aaaaggaaat ggacaatttt ctggctcaga tggaagcaaa gtactgcaaa tcttccaaag   3120

gaggagggaa aaaatctgct ctcaagaaag aaaagaaata atggaatttt tctcttcaaa   3180

ggtccttagg tgtaaattga tgccatcgta ggcaaggtgc aggcaggatt tgaaggcaaa   3240

agtcaattca gctcttgaga aaaggtgtct ttccagcctg aatttttcag attgactaga   3300

ccaagcagaa tctctcaacc tgatcttagt atttcctaga aagcacttga cattgtgtga   3360

ggtctcacct gaaggaactt ggtggtgaca tttgggaggg tggagggagg cagtgtcctt   3420

cctgacagca cttgcctcca tggatcttct gtacacagaa ctcttatcta ggatgtggtt   3480

ctgttcatgc tgctttctgc gatgtgcgtg tctgttagaa taggctctct acccagctag   3540

aacaccttcc agacacttgc tggacagcta tcttccacat acttcccagt ttacatttgg   3600

tcttaatgat cttgaataga tcctctcttc attttactca gccaggtttt gtactgatgt   3660

acaggtgtta aattacttca agcatttttg taagaggtgt atataattca ataaaaaagg   3720

taaaacatga tgattaagtt ctgggggctt tgtaaatgat cccactaaaa tgtgacctag   3780

gaaaaatatg aatggtgttt aggatgagag aaaaggggaa aacaatagcc ctggtcagct   3840

ttataataga gagcctggtt tccctagcat gaagagatgt atgttgtagt cctgccactg   3900

attactgaag tcctgccatt aattgctgaa tgtcttcagt tgggccactg agcttgtctg   3960

aatctgttcc cttttataaa agagttacta catcaaaaca aagagtgaaa tccaaatttg   4020

tcaaactgta tgtattaaac atgtccagtt ttttggttaa aaaaaaattg cactggcttt   4080

gagggaaaac acacagggtg agggaattgg gctaaatgac ttcttacagg cccctttctg   4140

attctttaac tttgaaaggc aagccatatt gatccagttg ttatagtgaa ctcatggtaa   4200

tggtttgtga gaacaataga gattttcatt tctatgtaga tgagttggta tgagaatata   4260

tggaattttt aagggactgt ttaaatcttt gatttgtaga ctattaaata taccgtatgc   4320

ataaagtaag cctttagctc taaggtaaag acgacacgtt ttcggtttgt gactacaaat   4380

aggttaaaaa tagattttaa ttttattaaa aatataattt aatgcaggtt gtttgaagca   4440

tctgtcttca tatgatggca ttagaacacc ttggtataat aaaaagttac cgtaatttat   4500

gattatttga atttatccat tctgaaaatt aataagatct aaaactggca tgacaatcaa   4560

gatttgtatt tagtgaaatt taaaataaat gtaagccata gtt                     4603


<210>  6969
<211>  260
<212>  PRT
<213>  Homo sapiens

<400>  6969

Met Gly Leu Leu Asp Leu Cys Glu Glu Val Phe Gly Thr Ala Asp Leu 
1               5                   10                  15


Tyr Arg Val Leu Gly Val Arg Arg Glu Ala Ser Asp Gly Glu Val Arg 
            20                  25                  30


Arg Gly Tyr His Lys Val Ser Leu Gln Val His Pro Asp Arg Val Gly 
        35                  40                  45


Glu Gly Asp Lys Glu Asp Ala Thr Arg Arg Phe Gln Ile Leu Gly Lys 
    50                  55                  60


Val Tyr Ser Val Leu Ser Asp Arg Glu Gln Arg Ala Val Tyr Asp Glu 
65                  70                  75                  80


Gln Gly Thr Val Asp Glu Asp Ser Pro Val Leu Thr Gln Asp Arg Asp 
                85                  90                  95


Trp Glu Ala Tyr Trp Arg Leu Leu Phe Lys Lys Ile Ser Leu Glu Asp 
            100                 105                 110


Ile Gln Ala Phe Glu Lys Thr Tyr Lys Gly Ser Glu Glu Glu Leu Ala 
        115                 120                 125


Asp Ile Lys Gln Ala Tyr Leu Asp Phe Lys Gly Asp Met Asp Gln Ile 
    130                 135                 140


Met Glu Ser Val Leu Cys Val Gln Tyr Thr Glu Glu Pro Arg Ile Arg 
145                 150                 155                 160


Asn Ile Ile Gln Gln Ala Ile Asp Ala Gly Glu Val Pro Ser Tyr Asn 
                165                 170                 175


Ala Phe Val Lys Glu Ser Lys Gln Lys Met Asn Ala Arg Lys Arg Arg 
            180                 185                 190


Ala Gln Glu Glu Ala Lys Glu Ala Glu Met Ser Arg Lys Glu Leu Gly 
        195                 200                 205


Leu Asp Glu Gly Val Asp Ser Leu Lys Ala Ala Ile Gln Ser Arg Gln 
    210                 215                 220


Lys Asp Arg Gln Lys Glu Met Asp Asn Phe Leu Ala Gln Met Glu Ala 
225                 230                 235                 240


Lys Tyr Cys Lys Ser Ser Lys Gly Gly Gly Lys Lys Ser Ala Leu Lys 
                245                 250                 255


Lys Glu Lys Lys 
            260


<210>  6970
<211>  3735
<212>  DNA
<213>  Homo sapiens

<400>  6970
cttattcttg tacttttctt tcttgctggt aattttatgg agcaggttaa gaaggctgct     60

ctgtgttagg ataaactgta taccaataat gttgacaacc tgtaatgagt gttgcatttt    120

acttcttgta tcttttcctt cctaccttga tgccagtaat ctataaggga tctttatagt    180

ttgaatgtat ttgaataact tcagtatact ttagttctac ttttttattt gactcacaac    240

cattcttagg tctcaagtat tcccatgtgt tttaaaagcc tgaagtcagt gagatgaaat    300

tcaacatcaa gaatttgaag taacttgtaa ggaaaaataa tataaagata ccattggggc    360

agtggctcac acctgtaatc tcagcacttt gggaggctga ggtggaagga tcacttgaag    420

ccagagtttg agaccagcct gtgcaacaca gcaagacccc gtctctacaa aaacttaaaa    480

aattagctgg ctgtggtgtt gctcacccat agttccagct actcgggaag ctgaggcagt    540

aagatcactt gagcccagga ggccgatgct gcagtgaact gtgattgttc cactacagtc    600

cagcctgggt gacagagaaa agaaaaagaa aacattacat aatttggcta gagcataata    660

atttgatttt ctggtttttg aaaatttgag ttgcaataaa aggatatttc agtgtgcgat    720

ttcaattttc cgtagcaaat gtatatatag aaaaatgtta aaatagatgt atttgaatac    780

cttaaaaaat acaagaaact ggaagaaaga taatattgca aagcatctac atatatccta    840

ggccttttgt gtacaaggtt atttgtgaca attgtaaggt attatgaagg caggtaggat    900

tatctccgtt ttacagatag ggaagctgag gcctagaggt ggaaacttgc ccagtgatgt    960

aagattcatc tcccggttat gccctcctgg aaagcccttc ccaacatatt atgttgtcca   1020

tagagggaaa aatgagcaaa gacagatggc ttaactctgg tgtgtgacta agatatagga   1080

aatttataga ggaggttcta tcaatgtgcc gacttacttt gtgttttatg ttctgagaac   1140

gattaccagc catctcaaat tctgtggttg tcaaagctcc cctggggttg ttgctggttg   1200

gcccccactt gctttgagac tttgatgcca gggcaggttg agaggaactg acttcagctg   1260

agtttgatct tggatctggg aaagagaaat gctttgaaaa tcacggcaac tctgggaagt   1320

ttaaaagata ttaatgtatc ctggagagtt tgaggctttg cagaaactta ttggcagagc   1380

agaatgattc tgaaaaatgc tacatcagtg aggggatatt tgataaggta ttttctgcca   1440

actcgggtat tcacttagca ttgtttatcc tttaagatat gtatacacat acttcctctg   1500

tgagtttacc ctactaacaa agttttatcc ccagcctcaa ccttgctttg ggtctccagg   1560

cccaagtttc tcaccatctc ttggatgatt gctccagccc actctgctgc cacctgggat   1620

ccaacatgtt caaacccagc tgtgaacttc acagagtatt aaaagaaaga gcctttgctt   1680

cagcagttta tgttattaag acggaggctt gggtcatgtt atctctctcc accaatgtgt   1740

aaggtgaaag tcctattagg taagagtttt tggaagaccc gtgttttgtg ctttttgggt   1800

ttcagtatag ggttttttcc tacagggcta gagggaaagt accccagcat ttccaaccag   1860

tggggtgcaa aattatttgg gtctacagct ttacctattc ctttcaagaa catttttgaa   1920

aaaacacatc tgttaagttg aaccatgtgt aactgctgaa tgctgatgtt tggccgtttt   1980

ctacttaaaa aaataggcca gcagtttgta aattcaagct aatatatgaa ctttttgaaa   2040

aagttgttct tggacactaa aaggtaagac ggacgccaga tttccagagc aaggggagga   2100

gagacccgag caacatcact tccctgaaga cctagctcct gcgcgcggcc ggggactgtg   2160

actccacatg ccggcgttac ttacccgggc ccgcgcctga ctcgccacac ctcattttgc   2220

ggccgccgta aagcgcggat gcgcggcgtg gccacgcccc ttcagtgctt gtgacgcagg   2280

cgccctgggc tttttgggcg cgaaaaagaa gcagtcctgg gttgtacccg gcgcagctgg   2340

gagcggctgc ttcctccggg gtcgtatctc cgcccggcat ggggctgctg gacctttgcg   2400

aggaagtgtt cggcaccgcc gacctttacc gggtgctggg cgtgcgacgc gaggcctccg   2460

acggcgaggt ccgacgaggc taccacaagg tgtccctgca ggtacacccg gaccgggtgg   2520

gtgagggcga caaggaggac gccacccgcc gcttccagat cctgggaaaa gtctattccg   2580

ttctcagtga cagagaacag agagcagtgt acgatgagca gggaacagtg gacgaggact   2640

ctcctgtgct cacccaagac cgagactggg aggcgtattg gcggctactc tttaaaaaga   2700

tatctttaga ggacattcaa gcttttgaaa agacatacaa aggttcggaa gaagagctgg   2760

ctgatattaa gcaggcctat ctggacttca agggtgacat ggatcagatc atggagtctg   2820

tgctttgcgt gcagtacaca gaggaaccca ggataaggaa tatcattcag caagctattg   2880

acgccggaga ggtcccatcc tataatgcct ttgtcaaaga atcgaaacaa aagatgaatg   2940

caaggaaaag gagggctcag gaagaggcca aagaagcaga aatgagcaga aaggagttgg   3000

ggcttgatga aggcgtggat agcctgaagg cagccattca gagcagacaa aaggatcggc   3060

aaaaggaaat ggacaatttt ctggctcaga tggaagcaaa gtactgcaaa tcttccaaag   3120

gaggagggaa aaaatctgct ctcaagaaag aaaagaaata atggaatttt tctcttcaaa   3180

ggtccttagg tgtaaattga tgccatcgta ggcaaggtgc aggcaggatt tgaaggcaaa   3240

agtcaattca gctcttgaga aaaggtgtct ttccagcctg aatttttcag attgactaga   3300

ccaagcagaa tctctcaacc tgatcttagt atttcctaga aagcacttga cattgtgtga   3360

ggtctcacct gaaggaactt ggtggtgaca tttgggaggg tggagggagg cagtgtcctt   3420

cctgacagca cttgcctcca tggatcttct gtacacagaa ctcttatcta ggatgtggtt   3480

ctgttcatgc tgctttctgc gatgtgcgtg tctgttagaa taggctctct acccagctag   3540

aacaccttcc agacacttgc tggacagcta tcttccacat acttcccagt ttacatttgg   3600

tcttaatgat cttgaataga tcctctcttc attttactca gccaggtttt gtactgatgt   3660

acaggtgtta aattacttca agcatttttg taagaggtgt atataattca ataaaaaagg   3720

taaaacatga tgatt                                                    3735


<210>  6971
<211>  260
<212>  PRT
<213>  Homo sapiens

<400>  6971

Met Gly Leu Leu Asp Leu Cys Glu Glu Val Phe Gly Thr Ala Asp Leu 
1               5                   10                  15


Tyr Arg Val Leu Gly Val Arg Arg Glu Ala Ser Asp Gly Glu Val Arg 
            20                  25                  30


Arg Gly Tyr His Lys Val Ser Leu Gln Val His Pro Asp Arg Val Gly 
        35                  40                  45


Glu Gly Asp Lys Glu Asp Ala Thr Arg Arg Phe Gln Ile Leu Gly Lys 
    50                  55                  60


Val Tyr Ser Val Leu Ser Asp Arg Glu Gln Arg Ala Val Tyr Asp Glu 
65                  70                  75                  80


Gln Gly Thr Val Asp Glu Asp Ser Pro Val Leu Thr Gln Asp Arg Asp 
                85                  90                  95


Trp Glu Ala Tyr Trp Arg Leu Leu Phe Lys Lys Ile Ser Leu Glu Asp 
            100                 105                 110


Ile Gln Ala Phe Glu Lys Thr Tyr Lys Gly Ser Glu Glu Glu Leu Ala 
        115                 120                 125


Asp Ile Lys Gln Ala Tyr Leu Asp Phe Lys Gly Asp Met Asp Gln Ile 
    130                 135                 140


Met Glu Ser Val Leu Cys Val Gln Tyr Thr Glu Glu Pro Arg Ile Arg 
145                 150                 155                 160


Asn Ile Ile Gln Gln Ala Ile Asp Ala Gly Glu Val Pro Ser Tyr Asn 
                165                 170                 175


Ala Phe Val Lys Glu Ser Lys Gln Lys Met Asn Ala Arg Lys Arg Arg 
            180                 185                 190


Ala Gln Glu Glu Ala Lys Glu Ala Glu Met Ser Arg Lys Glu Leu Gly 
        195                 200                 205


Leu Asp Glu Gly Val Asp Ser Leu Lys Ala Ala Ile Gln Ser Arg Gln 
    210                 215                 220


Lys Asp Arg Gln Lys Glu Met Asp Asn Phe Leu Ala Gln Met Glu Ala 
225                 230                 235                 240


Lys Tyr Cys Lys Ser Ser Lys Gly Gly Gly Lys Lys Ser Ala Leu Lys 
                245                 250                 255


Lys Glu Lys Lys 
            260


<210>  6972
<211>  4385
<212>  DNA
<213>  Homo sapiens

<400>  6972
ggggagagct ctcccaggcg cgatggaggc aacccgaacc tgaagcagcc acactgcctt     60

acatttgatc cttctctcag ttttttcccc acttaatcac cgctgaaaaa tttccacccc    120

attgaagcag ctaaggctcc gacaagctac tctcctctgc aaggcctacc gtgggggcca    180

cttaaccatc cgccttgccc tgggtggctg caccaatcgg ccgttctacc gcattgtggc    240

tgctcacaac aagtgtccca gggatggccg tttcgtagag cagctgggct cctatgatcc    300

attgcccaac agtcatggag aaaaactcgt tgccctcaac ctagacagga tccgtcattg    360

gattggctgc ggggcccacc tctctaagcc tatggaaaag cttctgggtc ttgctggctt    420

tttccctctg catcctatga tgatcacaaa tgctgagaga ctgcgaagga aacgggcacg    480

tgaagtcctg ttagcttctc agaaaacaga tgcagaagct acagatacag aggctacaga    540

aacataaatg agctgacttt agtgagcata gcagtgggaa caaggtcaag gtccttttga    600

aacactgcag cgatcttaat tttgttagat ttggagttca ataaatggag tatcctgagt    660

tgcccttgct cttctggcct ggcctgcaca gggcccaggg agagatttgt tcttgtgtga    720

cttagagctg ggtgtgggta ctaattagct tttttcgact ttgtcttggg atagacagtg    780

gctatgggag gattggactt ttgagttggg ctctgggtct cttggacaac tttacaattt    840

actggcttcc aagacttcct gcttcaaaac ccccagccag actattcatg gcccattcag    900

atcttcatgt tcatcccaca agtgcaagaa cagttaacct ttcttaattg atttttgtaa    960

ttggaggttt atattgtctt gcctaatgca tattctcttt tttttttttt ttttgagacg   1020

gagtcttgtt ctgttgccag gctggagtgc ggtggtgcaa tctcagctca ctgcaatctc   1080

cacctcctgg gttcaagagg ttctcctgcc tcagcctcct gagtagccgg ggagctacaa   1140

gcatgcacca ccacacccag ctaatttttt tttttttttt gagaggagtc tcgctctgtc   1200

gcccaggctt gagtgcagtg gcgcgatctc ggctcactgc aagctctgtc tcctgggttc   1260

atgccattct cctgcttcag cctcccgagt agtcccagga gtagctggga ctacaggtgc   1320

ccaccaccac acccagctaa tttttttgta tttttagtag agatggggtt tcaccatgtt   1380

atccaggatg gttttgatct cctgacctcg tgatccgccc gccttggcct cccaaaagtg   1440

ctgggattat aggcgtgagc caccgcccgg gcaaattttt gtatttttag tagagatggg   1500

gtttcaccgt gttggccagg atggtctcaa tctgaccttg tgatctgccc acctcggcct   1560

cccaaagtgc taggattact ggcgtgagcc accactccta gccttaatgc atattcttaa   1620

atatacaaag gtagatttgt tatgaaaatt gctttggggc tctaataacc taccttttaa   1680

gaatgagaaa ctgctgggct taagggagtt cagtatgaat caagattgaa ccattcaaat   1740

gtggctgtga tttctgcata tatcatagat gggatccttc tgagaatact ggaataggga   1800

attaggacac caagccaatt cagctgtgaa ccttattctt gtacttttct ttcttgctgg   1860

taattttatg gagcaggtta agaaggctgc tctgtgttag gataaactgt ataccaataa   1920

tgttgacaac ctgtaatgag tgttgcattt tacttcttgt atcttttcct tcctaccttg   1980

atgccagtaa tctataaggg atctttatag tttgaatgta tttgaataac ttcagtatac   2040

tttagttcta cttttttatt tgactcacaa ccattcttag gtctcaagta ttcccatgtg   2100

ttttaaaagc ctgaagtcag tgagatgaaa ttcaacatca agaatttgaa gtaacttgta   2160

aggaaaaata atataaagat accattgggg cagtggctca cacctgtaat ctcagcactt   2220

tgggaggctg aggtggaagg atcacttgaa gccagagttt gagaccagcc tgtgcaacac   2280

agcaagaccc cgtctctaca aaaacttaaa aaattagctg gctgtggtgt tgctcaccca   2340

tagttccagc tactcgggaa gctgaggcag taagatcact tgagcccagg aggccgatgc   2400

tgcagtgaac tgtgattgtt ccactacagt ccagcctggg tgacagagaa aagaaaaaga   2460

aaacattaca taatttggct agagcataat aatttgattt tctggttttt gaaaatttga   2520

gttgcaataa aaggatattt cagtgtgcga tttcaatttt ccgtagcaaa tgtatatata   2580

gaaaaatgtt aaaatagatg tatttgaata ccttaaaaaa tacaagaaac tggaagaaag   2640

ataatattgc aaagcatcta catatatcct aggccttttg tgtacaaggt tatttgtgac   2700

aattgtaagg tattatgaag gcaggtagga ttatctccgt tttacagata gggaagctga   2760

ggcctagagg tggaaacttg cccagtgatg taagattcat ctcccggtta tgccctcctg   2820

gaaagccctt cccaacatat tatgttgtcc atagagggaa aaatgagcaa agacagatgg   2880

cttaactctg gtgtgtgact aagatatagg aaatttatag aggaggttct atcaatgtgc   2940

cgacttactt tgtgttttat gttctgagaa cgattaccag ccatctcaaa ttctgtggtt   3000

gtcaaagctc ccctggggtt gttgctggtt ggcccccact tgctttgaga ctttgatgcc   3060

agggcaggtt gagaggaact gacttcagct gagtttgatc ttggatctgg gaaagagaaa   3120

tgctttgaaa atcacggcaa ctctgggaag tttaaaagat attaatgtat cctggagagt   3180

ttgaggcttt gcagaaactt attggcagag cagaatgatt ctgaaaaatg ctacatcagt   3240

gaggggatat ttgataaggt attttctgcc aactcgggta ttcacttagc attgtttatc   3300

ctttaagata tgtatacaca tacttcctct gtgagtttac cctactaaca aagttttatc   3360

cccagcctca accttgcttt gggtctccag gcccaagttt ctcaccatct cttggatgat   3420

tgctccagcc cactctgctg ccacctggga tccaacatgt tcaaacccag ctgtgaactt   3480

cacagagtat taaaagaaag agcctttgct tcagcagttt atgttattaa gacggaggct   3540

tgggtcatgt tatctctctc caccaatgtg taaggtgaaa gtcctattag gtaagagttt   3600

ttggaagacc cgtgttttgt gctttttggg tttcagtata gggttttttc ctacagggct   3660

agagggaaag taccccagca tttccaacca gtggggtgca aaattatttg ggtctacagc   3720

tttacctatt cctttcaaga acatttttga aaaaacacat ctgttaagtt gaaccatgtg   3780

taactgctga atgctgatgt ttggccgttt tctacttaaa aaaataggcc agcagtttgt   3840

aaattcaagc taatatatga actttttgaa aaagttgttc ttggacacta aaaggtaaga   3900

cggacgccag atttccagag caaggggagg agagacccga gcaacatcac ttccctgaag   3960

acctagctcc tgcgcgcggc cggggactgt gactccacat gccggcgtta cttacccggg   4020

cccgcgcctg actcgccaca cctcattttg cggccgccgt aaagcgcgga tgcgcggcgt   4080

ggccacgccc cttcagtgct tgtgacgcag gcgccctggg ctttttgggc gcgaaaaaga   4140

agcagtcctg ggttgtaccc ggcgcagctg ggagcggctg cttcctccgg ggtcgtatct   4200

ccgcccggca tggggctgct ggacctttgc gaggaagtgt tcggcaccgc cgacctttac   4260

cgggtgctgg gcgtgcgacg cgaggcctcc gacggcgagg tccgacgagg ctaccacaag   4320

gtgtccctgc aggtacaccc ggaccgggtg ggtgagggcg acaaggagga cgccacccgc   4380

cgctt                                                               4385


<210>  6973
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  6973

Met Glu Lys Leu Leu Gly Leu Ala Gly Phe Phe Pro Leu His Pro Met 
1               5                   10                  15


Met Ile Thr Asn Ala Glu Arg Leu Arg Arg Lys Arg Ala Arg Glu Val 
            20                  25                  30


Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu Ala Thr Asp Thr Glu Ala 
        35                  40                  45


Thr Glu Thr 
    50


<210>  6974
<211>  2790
<212>  DNA
<213>  Homo sapiens

<400>  6974
attgtgggaa gtatagggcg gcaagcggag gaggcgtggc gagcggatca tccgcttccg     60

gagtcgaggt tttcgggctt gtaccgcttg gcggtgcggc ctggtgtcgg cttgcaggtt    120

ctttctgtgt ttgttctctg ccctgccaag gccgtagagc tggtgcgtgc gggtagcggg    180

gctctccgag gagccgcacg ccggcggcac catggtccac ctcactactc tcctctgcaa    240

ggcctaccgt gggggccact taaccatccg ccttgccctg ggtggctgca ccaatcggcc    300

gttctaccgc attgtggctg ctcacaacaa gtgtcccagg gatggccgtt tcgtagagca    360

gctgggctcc tatgatccat tgcccaacag tcatggagaa aaactcgttg ccctcaacct    420

agacaggatc cgtcattgga ttggctgcgg ggcccacctc tctaagccta tggaaaagct    480

tctgggtctc aagtattccc atgtgtttta aaagcctgaa gtcagtgaga tgaaattcaa    540

catcaagaat ttgaagtaac ttgtaaggaa aaataatata aagataccat tggggcagtg    600

gctcacacct gtaatctcag cactttggga ggctgaggtg gaaggatcac ttgaagccag    660

agtttgagac cagcctgtgc aacacagcaa gaccccgtct ctacaaaaac ttaaaaaatt    720

agctggctgt ggtgttgctc acccatagtt ccagctactc gggaagctga ggcagtaaga    780

tcacttgagc ccaggaggcc gatgctgcag tgaactgtga ttgttccact acagtccagc    840

ctgggtgaca gagaaaagaa aaagaaaaca ttacataatt tggctagagc ataataattt    900

gattttctgg tttttgaaaa tttgagttgc aataaaagga tatttcagtg tgcgatttca    960

attttccgta gcaaatgtat atatagaaaa atgttaaaat agatgtattt gaatacctta   1020

aaaaatacaa gaaactggaa gaaagataat attgcaaagc atctacatat atcctaggcc   1080

ttttgtgtac aaggttattt gtgacaattg taaggtatta tgaaggcagg taggattatc   1140

tccgttttac agatagggaa gctgaggcct agaggtggaa acttgcccag tgatgtaaga   1200

ttcatctccc ggttatgccc tcctggaaag cccttcccaa catattatgt tgtccataga   1260

gggaaaaatg agcaaagaca gatggcttaa ctctggtgtg tgactaagat ataggaaatt   1320

tatagaggag gttctatcaa tgtgccgact tactttgtgt tttatgttct gagaacgatt   1380

accagccatc tcaaattctg tggttgtcaa agctcccctg gggttgttgc tggttggccc   1440

ccacttgctt tgagactttg atgccagggc aggttgagag gaactgactt cagctgagtt   1500

tgatcttgga tctgggaaag agaaatgctt tgaaaatcac ggcaactctg ggaagtttaa   1560

aagatattaa tgtatcctgg agagtttgag gctttgcaga aacttattgg cagagcagaa   1620

tgattctgaa aaatgctaca tcagtgaggg gatatttgat aaggtatttt ctgccaactc   1680

gggtattcac ttagcattgt ttatccttta agatatgtat acacatactt cctctgtgag   1740

tttaccctac taacaaagtt ttatccccag cctcaacctt gctttgggtc tccaggccca   1800

agtttctcac catctcttgg atgattgctc cagcccactc tgctgccacc tgggatccaa   1860

catgttcaaa cccagctgtg aacttcacag agtattaaaa gaaagagcct ttgcttcagc   1920

agtttatgtt attaagacgg aggcttgggt catgttatct ctctccacca atgtgtaagg   1980

tgaaagtcct attaggtaag agtttttgga agacccgtgt tttgtgcttt ttgggtttca   2040

gtatagggtt ttttcctaca gggctagagg gaaagtaccc cagcatttcc aaccagtggg   2100

gtgcaaaatt atttgggtct acagctttac ctattccttt caagaacatt tttgaaaaaa   2160

cacatctgtt aagttgaacc atgtgtaact gctgaatgct gatgtttggc cgttttctac   2220

ttaaaaaaat aggccagcag tttgtaaatt caagctaata tatgaacttt ttgaaaaagt   2280

tgttcttgga cactaaaagg taagacggac gccagatttc cagagcaagg ggaggagaga   2340

cccgagcaac atcacttccc tgaagaccta gctcctgcgc gcggccgggg actgtgactc   2400

cacatgccgg cgttacttac ccgggcccgc gcctgactcg ccacacctca ttttgcggcc   2460

gccgtaaagc gcggatgcgc ggcgtggcca cgccccttca gtgcttgtga cgcaggcgcc   2520

ctgggctttt tgggcgcgaa aaagaagcag tcctgggttg tacccggcgc agctgggagc   2580

ggctgcttcc tccggggtcg tatctccgcc cggcatgggg ctgctggacc tttgcgagga   2640

agtgttcggc accgccgacc tttaccgggt gctgggcgtg cgacgcgagg cctccgacgg   2700

cgaggtccga cgaggctacc acaaggtgtc cctgcaggta cacccggacc gggtgggtga   2760

gggcgacaag gaggacgcca cccgccgctt                                    2790


<210>  6975
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  6975

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Leu Lys Tyr Ser 
                85                  90                  95


His Val Phe 



<210>  6976
<211>  4465
<212>  DNA
<213>  Homo sapiens

<400>  6976
gcattgtggg aagtataggg cggcaagcgg aggaggcgtg gcgagcggat catccgcttc     60

cggagtcgag gttttcgggc ttgtaccgct tggcggtgcg gcctggtgtc ggcttgcagg    120

ttctttctgt gtttgttctc tgccctgcca aggccgtaga gctggtgcgt gcgggtagcg    180

gggctctccg aggagccgca cgccggcggc accatggtcc acctcactac tctcctctgc    240

aaggcctacc gtgggggcca cttaaccatc cgccttgccc tgggtggctg caccaatcgg    300

ccgttctacc gcattgtggc tgctcacaac aagtgtccca gggatggccg tttcgtagag    360

cagctgggct cctatgatcc attgcccaac agtcatggag aaaaactcgt tgccctcaac    420

ctagacagga tccgtcattg gattggctgc ggggcccacc tctctaagcc tatggaaaag    480

cttctgggtc ttgctggctt tttccctctg catcctatga tgatcacaaa tgctgagaga    540

ctgcgaagga aacgggcacg tgaagtcctg ttagcttctc agaaaacaga tgcagaagct    600

acagatacag aggctacaga aacataaatg agctgacttt agtgagcata gcagtgggaa    660

caaggtcaag gtccttttga aacactgcag cgatcttaat tttgttagat ttggagttca    720

ataaatggag tatcctgagt tgcccttgct cttctggcct ggcctgcaca gggcccaggg    780

agagatttgt tcttgtgtga cttagagctg ggtgtgggta ctaattagct tttttcgact    840

ttgtcttggg atagacagtg gctatgggag gattggactt ttgagttggg ctctgggtct    900

cttggacaac tttacaattt actggcttcc aagacttcct gcttcaaaac ccccagccag    960

actattcatg gcccattcag atcttcatgt tcatcccaca agtgcaagaa cagttaacct   1020

ttcttaattg atttttgtaa ttggaggttt atattgtctt gcctaatgca tattctcttt   1080

tttttttttt ttttgagacg gagtcttgtt ctgttgccag gctggagtgc ggtggtgcaa   1140

tctcagctca ctgcaatctc cacctcctgg gttcaagagg ttctcctgcc tcagcctcct   1200

gagtagccgg ggagctacaa gcatgcacca ccacacccag ctaatttttt tttttttttt   1260

gagaggagtc tcgctctgtc gcccaggctt gagtgcagtg gcgcgatctc ggctcactgc   1320

aagctctgtc tcctgggttc atgccattct cctgcttcag cctcccgagt agtcccagga   1380

gtagctggga ctacaggtgc ccaccaccac acccagctaa tttttttgta tttttagtag   1440

agatggggtt tcaccatgtt atccaggatg gttttgatct cctgacctcg tgatccgccc   1500

gccttggcct cccaaaagtg ctgggattat aggcgtgagc caccgcccgg gcaaattttt   1560

gtatttttag tagagatggg gtttcaccgt gttggccagg atggtctcaa tctgaccttg   1620

tgatctgccc acctcggcct cccaaagtgc taggattact ggcgtgagcc accactccta   1680

gccttaatgc atattcttaa atatacaaag gtagatttgt tatgaaaatt gctttggggc   1740

tctaataacc taccttttaa gaatgagaaa ctgctgggct taagggagtt cagtatgaat   1800

caagattgaa ccattcaaat gtggctgtga tttctgcata tatcatagat gggatccttc   1860

tgagaatact ggaataggga attaggacac caagccaatt cagctgtgaa ccttattctt   1920

gtacttttct ttcttgctgg taattttatg gagcaggtta agaaggctgc tctgtgttag   1980

gataaactgt ataccaataa tgttgacaac ctgtaatgag tgttgcattt tacttcttgt   2040

atcttttcct tcctaccttg atgccagtaa tctataaggg atctttatag tttgaatgta   2100

tttgaataac ttcagtatac tttagttcta cttttttatt tgactcacaa ccattcttag   2160

gtctcaagta ttcccatgtg ttttaaaagc ctgaagtcag tgagatgaaa ttcaacatca   2220

agaatttgaa gtaacttgta aggaaaaata atataaagat accattgggg cagtggctca   2280

cacctgtaat ctcagcactt tgggaggctg aggtggaagg atcacttgaa gccagagttt   2340

gagaccagcc tgtgcaacac agcaagaccc cgtctctaca aaaacttaaa aaattagctg   2400

gctgtggtgt tgctcaccca tagttccagc tactcgggaa gctgaggcag taagatcact   2460

tgagcccagg aggccgatgc tgcagtgaac tgtgattgtt ccactacagt ccagcctggg   2520

tgacagagaa aagaaaaaga aaacattaca taatttggct agagcataat aatttgattt   2580

tctggttttt gaaaatttga gttgcaataa aaggatattt cagtgtgcga tttcaatttt   2640

ccgtagcaaa tgtatatata gaaaaatgtt aaaatagatg tatttgaata ccttaaaaaa   2700

tacaagaaac tggaagaaag ataatattgc aaagcatcta catatatcct aggccttttg   2760

tgtacaaggt tatttgtgac aattgtaagg tattatgaag gcaggtagga ttatctccgt   2820

tttacagata gggaagctga ggcctagagg tggaaacttg cccagtgatg taagattcat   2880

ctcccggtta tgccctcctg gaaagccctt cccaacatat tatgttgtcc atagagggaa   2940

aaatgagcaa agacagatgg cttaactctg gtgtgtgact aagatatagg aaatttatag   3000

aggaggttct atcaatgtgc cgacttactt tgtgttttat gttctgagaa cgattaccag   3060

ccatctcaaa ttctgtggtt gtcaaagctc ccctggggtt gttgctggtt ggcccccact   3120

tgctttgaga ctttgatgcc agggcaggtt gagaggaact gacttcagct gagtttgatc   3180

ttggatctgg gaaagagaaa tgctttgaaa atcacggcaa ctctgggaag tttaaaagat   3240

attaatgtat cctggagagt ttgaggcttt gcagaaactt attggcagag cagaatgatt   3300

ctgaaaaatg ctacatcagt gaggggatat ttgataaggt attttctgcc aactcgggta   3360

ttcacttagc attgtttatc ctttaagata tgtatacaca tacttcctct gtgagtttac   3420

cctactaaca aagttttatc cccagcctca accttgcttt gggtctccag gcccaagttt   3480

ctcaccatct cttggatgat tgctccagcc cactctgctg ccacctggga tccaacatgt   3540

tcaaacccag ctgtgaactt cacagagtat taaaagaaag agcctttgct tcagcagttt   3600

atgttattaa gacggaggct tgggtcatgt tatctctctc caccaatgtg taaggtgaaa   3660

gtcctattag gtaagagttt ttggaagacc cgtgttttgt gctttttggg tttcagtata   3720

gggttttttc ctacagggct agagggaaag taccccagca tttccaacca gtggggtgca   3780

aaattatttg ggtctacagc tttacctatt cctttcaaga acatttttga aaaaacacat   3840

ctgttaagtt gaaccatgtg taactgctga atgctgatgt ttggccgttt tctacttaaa   3900

aaaataggcc agcagtttgt aaattcaagc taatatatga actttttgaa aaagttgttc   3960

ttggacacta aaaggtaaga cggacgccag atttccagag caaggggagg agagacccga   4020

gcaacatcac ttccctgaag acctagctcc tgcgcgcggc cggggactgt gactccacat   4080

gccggcgtta cttacccggg cccgcgcctg actcgccaca cctcattttg cggccgccgt   4140

aaagcgcgga tgcgcggcgt ggccacgccc cttcagtgct tgtgacgcag gcgccctggg   4200

ctttttgggc gcgaaaaaga agcagtcctg ggttgtaccc ggcgcagctg ggagcggctg   4260

cttcctccgg ggtcgtatct ccgcccggca tggggctgct ggacctttgc gaggaagtgt   4320

tcggcaccgc cgacctttac cgggtgctgg gcgtgcgacg cgaggcctcc gacggcgagg   4380

tccgacgagg ctaccacaag gtgtccctgc aggtacaccc ggaccgggtg ggtgagggcg   4440

acaaggagga cgccacccgc cgctt                                         4465


<210>  6977
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  6977

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Leu Ala Gly Phe 
                85                  90                  95


Phe Pro Leu His Pro Met Met Ile Thr Asn Ala Glu Arg Leu Arg Arg 
            100                 105                 110


Lys Arg Ala Arg Glu Val Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu 
        115                 120                 125


Ala Thr Asp Thr Glu Ala Thr Glu Thr 
    130                 135


<210>  6978
<211>  1167
<212>  DNA
<213>  Homo sapiens

<400>  6978
tgttaaaata gatgtatttg aataccttaa aaaatacaag aaactggaag aaagataata     60

ttgcaaagca tctacatata tcctaggcct tttgtgtaca aggttatttg tgacaattgt    120

aaggtattat gaaggcaggt aggattatct ccgttttaca gatagggaag ctgaggccta    180

gaggtggaaa cttgcccagt gatgtaagat tcatctcccg gttatgccct cctggaaagc    240

ccttcccaac atattatgtt gtccatagag ggaaaaatga gcaaagacag atggcttaac    300

tctggtgtgt gactaagata taggaaattt atagaggagg ttctatcaat gtgccgactt    360

actttgtgtt ttatgttctg agaacgatta ccagccatct caaattctgt ggttgtcaaa    420

gctcccctgg ggttgttgct ggttggcccc cacttgcttt gagactttga tgccagggca    480

ggttgagagg aactgacttc agctgagttt gatcttggat ctgggaaaga gaaatgcttt    540

gaaaatcacg gcaactctgg gaagtttaaa agatattaat gtatcctgga gagtttgagg    600

ctttgcagaa acttattggc agagcagaat gattctgaaa aatgctacat cagtgagggg    660

atatttgata aggtattttc tgccaactcg ggtattcact tagcattgtt tatcctttaa    720

gatatgtata cacatacttc ctctgtgagt ttaccctact aacaaagttt tatccccagc    780

ctcaaccttg ctttgggtct ccaggcccaa gtttctcacc atctcttgga tgattgctcc    840

agcccactct gctgccacct gggatccaac atgttcaaac ccagctgtga acttcacaga    900

gtattaaaag aaagagcctt tgcttcagca gtttatgtta ttaagacgga ggcttgggtc    960

atgttatctc tctccaccaa tgtgtaaggt gaaagtccta ttaggtaaga cggacgccag   1020

atttccagag caaggggagg agagacccga gcaacatcac ttccctgaag acctagctcc   1080

tgcgcgcggc cggggactgt gactccacat gccggcgtta cttacccggg cccgcgcctg   1140

actcgccaca cctcattttg cggccgc                                       1167


<210>  6979
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  6979

Met Leu Leu Arg Arg Arg Leu Gly Ser Cys Tyr Leu Ser Pro Pro Met 
1               5                   10                  15


Cys Lys Val Lys Val Leu Leu Gly Lys Thr Asp Ala Arg Phe Pro Glu 
            20                  25                  30


Gln Gly Glu Glu Arg Pro Glu Gln His His Phe Pro Glu Asp Leu Ala 
        35                  40                  45


Pro Ala Arg Gly Arg Gly Leu 
    50                  55


<210>  6980
<211>  3573
<212>  DNA
<213>  Homo sapiens

<400>  6980
aaactgctgg cctatttttt taagtagaaa acggccaaac atcagcattc agcagttaca     60

catggttcaa cttaacagat gtgttttttc aaaaatgttc ttgaaaggaa taggtaaagc    120

tgtagaccca aataattttg caccccactg gttggaaatg ctggggtact ttccctctag    180

ccctgtagga aaaaacccta tactgaaacc caaaaagcac aaaacacggg tcttccaaaa    240

actcttacct aataggactt tcaccttaca cattggtgga gagagataac atgacccaag    300

cctccgtctt aataacataa actgctgaag caaaggctct ttcttttaat actctgtgaa    360

gttcacagct gggtttgaac atgttggatc ccaggtggca gcagagtggg ctggagcaat    420

catccaagag atggtgagaa acttgggcct ggagacccaa agcaaggttg aggctgggga    480

taaaactttg ttagtagggt aaactcacag aggaagtatg tgtatacata tcttaaagga    540

taaacaatgc taagtgaata cccgagttgg cagaaaatac cttatcaaat atcccctcac    600

tgatgtagca tttttcagaa tcattctgct ctgccaataa gtttctgcaa agcctcaaac    660

tctccaggat acattaatat cttttaaact tcccagagtt gccgtgattt tcaaagcatt    720

tctctttccc agatccaaga tcaaactcag ctgaagtcag ttcctctcaa cctgccctgg    780

catcaaagtc tcaaagcaag tgggggccaa ccagcaacaa ccccagggga gctttgacaa    840

ccacagaatt tgagatggct ggtaatcgtt ctcagaacat aaaacacaaa cagacagccc    900

tgattgctat tccaatgtca tcacaaaccc ccaggatgct tggaaggcca aggaatcaag    960

gtcagctgta tccacagccc tagtctcaag ccttcatcct cttacccgat agcaggcgat   1020

tcccagtcct agccagatag atgagcccca gtctcaggaa gatgaagtgc atctcagaag   1080

catccactac aaagctaatg gttcgttcat agcatgcctt ggcctcagaa tgatttccac   1140

tcagaaaata gagatggccc ttcaggcccc agacattggg gttctgggaa agtgaaaagc   1200

aagtagtata tgggataagg tagtatttaa aagtaccttg atgatctttg tttaacattt   1260

aaatttagat agattgtcca tttcctttct cttttctttt tcagatcaac cgttttcttt   1320

ttctaagagc actcagaaac ataaccattt aattgtacaa ggagacattt ttctagctct   1380

gccctcagat ttctttcttg cattcttcaa agccattttg ggtgtggagt aaatattaag   1440

aaaaacattc aagcataacc ccaatactgt tcacatgaga aaatataaga aatctagaaa   1500

aattgaaata aacactatca gctaaagata tccttttctc tgctctttgc aaaactcatg   1560

attactttat tattattatt ttttgagatg gagtcttgca ctgtcgccca ggctggagag   1620

tgcaatggct caatctccgc tcactgcaac ctccgcctcc caggttcagg cgagtctcct   1680

gcctcaccct cctgagtagc tgggattaca ggcacctgcc accacgccca tctaattttt   1740

tgtattttta gtagagatgg ggtttcacta tgttggccag gctggtcttg aactcctgac   1800

ctcgtgatct gcctgcctcg gcctcccaaa gtgctgcgat tacagttgtg agccaccgcg   1860

cccagccaac tcatgattac ttaagaaaag caaatggaag ggtatagaga gatgagttta   1920

ctgacagctg atgaccaccc ttctgttcac cagaaatcta cgtgtgatat ggcatcacca   1980

cctttaaata aagccccttc tccagactca agaggcttta gcaaaagtca ttaccaggta   2040

gtccatctgg gctgcttgtt gaaggtattc ctctgccttg gcaaagttct tcttaagaat   2100

gtgtgtttgg gccagcacca agtaatattc acagctgggg cctccttgag ggcataacag   2160

ctcatgtgca agcactctgt gcacatactg caaggataat cagattataa gcaacatata   2220

aatggctgca ttgcgtcttt ttcggttgaa ggattctgtc tctgataata aataatacga   2280

aatgtattac agaatgaaat aattatcctc aacttcaaaa ggtaaagggt gaattacaaa   2340

cattctgcac ttcatagttc cattaccagc tattcaccta gtcaccaaat gaagacatta   2400

ccaagtgaat aacttgcaat attgtacaat tctggtcttg ctggtcatca tactaggtga   2460

gtgttagact gcatgtatta tgcagcagac aaaggcacat catcaaccac cccatttaca   2520

aaggaggtaa cattttcagg cagctgacat tgtaaggaaa cttaagtgag gtaaaactgc   2580

ctttctaaca atctagactt gaaatcttag aaacataaat gtctgttttg gatccacctc   2640

caaacattgg ttatgtttac cagttttgta gtttgggtca atttttgtat tttgtttttt   2700

tttttttctt tttttagaga cagggtctta ctctgtcacc cagggctgct tactgcagcc   2760

ttctggcctc aagcaatcct cctgccttgg cttcccaaaa gtgctggaat tataggggtg   2820

agccccatgc ctggccaaat ctttgctttt tacactttat aagacctaca aaattaacaa   2880

agttagatat acttcttaag tcgagggtaa atccttcttt tcatctccca ctgttcccat   2940

ctcagcctat aatgtagaaa attctacatt atacttacac ctttttagga gaatactaga   3000

gggaacagct gcagctattt tttccacctg ccttctgggt ctctgacctg ggggagctaa   3060

tgacttattt agctgtggaa gaagagagtc tgtttctatt ttgcggaggg ttaatgtgtt   3120

aaagcctcct gcttaatgtg gctcaatccc acccagttaa taattcttgc cctttcttga   3180

gcttgcctgc ccttgagtag ggcatgcact tggcaggatc aaaaccaaac actcctggct   3240

cctgagtctt gatctctcct actgcttgct catgaatatg cttctttctt cccatgtaat   3300

aggcagactt cctagaatgc tcttcttctc tgagaggagg cttcaattct tcagctgctc   3360

tacctgtgac tgcatgggta agtcaaatgt ggggctagtt atgttgtcca gccaagtttt   3420

accaataaaa ataagctaat atttttattc ccccacatag tactgtgtat gtttctagtt   3480

ggatctaacc tagaagggaa gaagggaatg atttggctcc tgtgaacccc caacactcac   3540

aaaatgaatt cccataataa agtgatatca ggc                                3573


<210>  6981
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  6981

Met Ala Gly Asn Arg Ser Gln Asn Ile Lys His Lys Gln Thr Ala Leu 
1               5                   10                  15


Ile Ala Ile Pro Met Ser Ser Gln Thr Pro Arg Met Leu Gly Arg Pro 
            20                  25                  30


Arg Asn Gln Gly Gln Leu Tyr Pro Gln Pro 
        35                  40


<210>  6982
<211>  323
<212>  DNA
<213>  Homo sapiens

<400>  6982
gtcagttcct ctcaacctgc cctggcatca aagtctcaaa gcaagtgggg gccaaccagc     60

aacaacccca ggggagcttt gacaaccaca gaatttgaga tggctggtaa tcgttctcag    120

aacataaaac acaaacggtc ccatcaggac atctataaac catggagttt caggtgcaag    180

gttggaaatc cacaggaact cactctcatg tgtgcatcat tcagtgattt ctccacacac    240

agtgggctgt cagatacatt tatagttttt tttctttaca ttgtgcatcc ttttcttgag    300

gtaaaaatct gatttgcctg ttg                                            323


<210>  6983
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  6983

Met Ala Gly Asn Arg Ser Gln Asn Ile Lys His Lys Arg Ser His Gln 
1               5                   10                  15


Asp Ile Tyr Lys Pro Trp Ser Phe Arg Cys Lys Val Gly Asn Pro Gln 
            20                  25                  30


Glu Leu Thr Leu Met Cys Ala Ser Phe Ser Asp Phe Ser Thr His Ser 
        35                  40                  45


Gly Leu Ser Asp Thr Phe Ile Val Phe Phe Leu Tyr Ile Val His Pro 
    50                  55                  60


Phe Leu Glu Val Lys Ile 
65                  70


<210>  6984
<211>  1323
<212>  DNA
<213>  Homo sapiens

<400>  6984
ccaggggagc tttgacaacc acagaatttg agatggctgg taatcgttct cagaacataa     60

aacacaaagc tggactgtag tggaacaatc acagttcact gcagcatcgg cctcctgggc    120

tcaagtgatc ttactgcctc agcttcccga gtagctggaa ctatgggtga gcaacaccac    180

agccagctaa ttttttaagt ttttgtagag acggggtctt gctgtgttgc acaggctggt    240

ctcaaactct ggcttcaagt gatccttcca cctcagcctc ccaaagtgct gagattacag    300

gtgtgagcca ctgccccaat ggtatcttta tattattttt ccttacaagt tacttcaaat    360

tcttgatgtt gaatttcatc tcactgactt caggctttta aaacacatgg gaatacttga    420

gacctaagaa tggttgtgag tcaaataaaa aagtagaact aaagtatact gaagttattc    480

aaatacattc aaactataaa gatcccttat agattactgg catcaaggta ggaaggaaaa    540

gatacaagaa gtaaaatgca acactcatta caggttgtca acattattgg tatacagttt    600

atcctaacac agagcagcct tcttaacctg ctccataaaa ttaccagcaa gaaagaaaag    660

tacaagaata aggttcacag ctgaattggc ttggtgtcct aattccctat tccagtattc    720

tcagaaggat cccatctatg atatatgcag aaatcacagc cacatttgaa tggttcaatc    780

ttgattcata ctgaactccc ttaagcccag cagtttctca ttcttaaaag gtaggttatt    840

agagccccaa agcaattttc ataacaaatc tacctttgta tatttaagaa tatgcattaa    900

ggctaggagt ggtggctcac gccagtaatc ctagcacttt gggaggccga ggtgggcaga    960

tcacaaggtc agattgagac catcctggcc aacacggtga aaccccatct ctactaaaaa   1020

tacaaaaatt tgcccgggcg gtggctcacg cctataatcc cagcactttt gggaggccaa   1080

ggcgggcgga tcacgaggtc aggagatcaa aaccatcctg gataacatgg tgaaacccca   1140

tctctactaa aaatacaaaa aaattagctg ggtgtggtgg tgggcacctg tagtcccagc   1200

tactcctggg actactcggg aggctgaagc aggagaatgg catgaaccca ggagacagag   1260

cttgcagtga gccgagatcg cgccactgca ctcaagcctg ggcgacagag cgagactcct   1320

ctc                                                                 1323


<210>  6985
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  6985

Met Gln His Ser Leu Gln Val Val Asn Ile Ile Gly Ile Gln Phe Ile 
1               5                   10                  15


Leu Thr Gln Ser Ser Leu Leu Asn Leu Leu His Lys Ile Thr Ser Lys 
            20                  25                  30


Lys Glu Lys Tyr Lys Asn Lys Val His Ser 
        35                  40


<210>  6986
<211>  2554
<212>  DNA
<213>  Homo sapiens

<400>  6986
ggggagagct ctcccaggcg cgatggaggc aacccgaacc tgaagcagcc acactgcctt     60

acatttgatc cttctctcag ttttttcccc acttaatcac cgctgaaaaa tttccacccc    120

attgaagcag ctaaggctcc gacaagctac tctcctctgc aaggcctacc gtgggggcca    180

cttaaccatc cgccttgccc tgggtggctg caccaatcgg ccgttctacc gcattgtggc    240

tgctcacaac aagtgtccca gggatggccg tttcgtagag cagctgggct cctatgatcc    300

attgcccaac agtcatggag aaaaactcgt tgccctcaac ctagacagga tccgtcattg    360

gattggctgc ggggcccacc tctctaagcc tatggaaaag cttctgggtc ttgctggctt    420

tttccctctg catcctatga tgatcacaaa tgctgagaga ctgcgaagga aacgggcacg    480

tgaagtcctg ttagcttctc agaaaacaga tgcagaagct acagatacag aggctacaga    540

aacataaatg agctgacttt agtgagcata gcagtgggaa caaggtcaag gtccttttga    600

aacactgcag cgatcttaat tttgttagat ttggagttca ataaatggag tatcctgagt    660

tgcccttgct cttctggcct ggcctgcaca gggcccaggg agagatttgt tcttgtgtga    720

cttagagctg ggtgtgggta ctaattagct tttttcgact ttgtcttggg atagacagtg    780

gctatgggag gattggactt ttgagttggg ctctgggtct cttggacaac tttacaattt    840

actggcttcc aagacttcct gcttcaaaac ccccagccag actattcatg gcccattcag    900

atcttcatgt tcatcccaca agtgcaagaa cagttaacct ttcttaattg atttttgtaa    960

ttggaggttt atattgtctt gcctaatgca tattctcttt tttttttttt ttttgagacg   1020

gagtcttgtt ctgttgccag gctggagtgc ggtggtgcaa tctcagctca ctgcaatctc   1080

cacctcctgg gttcaagagg ttctcctgcc tcagcctcct gagtagccgg ggagctacaa   1140

gcatgcacca ccacacccag ctaatttttt tttttttttt gagaggagtc tcgctctgtc   1200

gcccaggctt gagtgcagtg gcgcgatctc ggctcactgc aagctctgtc tcctgggttc   1260

atgccattct cctgcttcag cctcccgagt agtcccagga gtagctggga ctacaggtgc   1320

ccaccaccac acccagctaa tttttttgta tttttagtag agatggggtt tcaccatgtt   1380

atccaggatg gttttgatct cctgacctcg tgatccgccc gccttggcct cccaaaagtg   1440

ctgggattat aggcgtgagc caccgcccgg gcaaattttt gtatttttag tagagatggg   1500

gtttcaccgt gttggccagg atggtctcaa tctgaccttg tgatctgccc acctcggcct   1560

cccaaagtgc taggattact ggcgtgagcc accactccta gccttaatgc atattcttaa   1620

atatacaaag gtagatttgt tatgaaaatt gctttggggc tctaataacc taccttttaa   1680

gaatgagaaa ctgctgggct taagggagtt cagtatgaat caagattgaa ccattcaaat   1740

gtggctgtga tttctgcata tatcatagat gggatccttc tgagaatact ggaataggga   1800

attaggacac caagccaatt cagctgtgaa ccttattctt gtacttttct ttcttgctgg   1860

taattttatg gagcaggtta agaaggctgc tctgtgttag gataaactgt ataccaataa   1920

tgttgacaac ctgtaatgag tgttgcattt tacttcttgt atcttttcct tcctaccttg   1980

atgccagtaa tctataaggg atctttatag tttgaatgta tttgaataac ttcagtatac   2040

tttagttcta cttttttatt tgactcacaa ccattcttag gtctcaagta ttcccatgtg   2100

ttttaaaagc ctgaagtcag tgagatgaaa ttcaacatca agaatttgaa gtaacttgta   2160

aggaaaaata atataaagat accattgggg cagtggctca cacctgtaat ctcagcactt   2220

tgggaggctg aggtggaagg atcacttgaa gccagagttt gagaccagcc tgtgcaacac   2280

agcaagaccc cgtctctaca aaaacttaaa aaattagctg gctgtggtgt tgctcaccca   2340

tagttccagc tactcgggaa gctgaggcag taagatcact tgagcccagg aggccgatgc   2400

tgcagtgaac tgtgattgtt ccactacagt ccagcctggg tgacagagaa aagaaaaaga   2460

aaacattaca taatttggct agagcataat aatttgattt tctggttttt gaaaatttga   2520

gttgcaataa aaggatattt cagtgtgcga tttc                               2554


<210>  6987
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  6987

Met Glu Lys Leu Leu Gly Leu Ala Gly Phe Phe Pro Leu His Pro Met 
1               5                   10                  15


Met Ile Thr Asn Ala Glu Arg Leu Arg Arg Lys Arg Ala Arg Glu Val 
            20                  25                  30


Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu Ala Thr Asp Thr Glu Ala 
        35                  40                  45


Thr Glu Thr 
    50


<210>  6988
<211>  959
<212>  DNA
<213>  Homo sapiens

<400>  6988
attgtgggaa gtatagggcg gcaagcggag gaggcgtggc gagcggatca tccgcttccg     60

gagtcgaggt tttcgggctt gtaccgcttg gcggtgcggc ctggtgtcgg cttgcaggtt    120

ctttctgtgt ttgttctctg ccctgccaag gccgtagagc tggtgcgtgc gggtagcggg    180

gctctccgag gagccgcacg ccggcggcac catggtccac ctcactactc tcctctgcaa    240

ggcctaccgt gggggccact taaccatccg ccttgccctg ggtggctgca ccaatcggcc    300

gttctaccgc attgtggctg ctcacaacaa gtgtcccagg gatggccgtt tcgtagagca    360

gctgggctcc tatgatccat tgcccaacag tcatggagaa aaactcgttg ccctcaacct    420

agacaggatc cgtcattgga ttggctgcgg ggcccacctc tctaagccta tggaaaagct    480

tctgggtctc aagtattccc atgtgtttta aaagcctgaa gtcagtgaga tgaaattcaa    540

catcaagaat ttgaagtaac ttgtaaggaa aaataatata aagataccat tggggcagtg    600

gctcacacct gtaatctcag cactttggga ggctgaggtg gaaggatcac ttgaagccag    660

agtttgagac cagcctgtgc aacacagcaa gaccccgtct ctacaaaaac ttaaaaaatt    720

agctggctgt ggtgttgctc acccatagtt ccagctactc gggaagctga ggcagtaaga    780

tcacttgagc ccaggaggcc gatgctgcag tgaactgtga ttgttccact acagtccagc    840

ctgggtgaca gagaaaagaa aaagaaaaca ttacataatt tggctagagc ataataattt    900

gattttctgg tttttgaaaa tttgagttgc aataaaagga tatttcagtg tgcgatttc     959


<210>  6989
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  6989

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Leu Lys Tyr Ser 
                85                  90                  95


His Val Phe 



<210>  6990
<211>  2634
<212>  DNA
<213>  Homo sapiens

<400>  6990
gcattgtggg aagtataggg cggcaagcgg aggaggcgtg gcgagcggat catccgcttc     60

cggagtcgag gttttcgggc ttgtaccgct tggcggtgcg gcctggtgtc ggcttgcagg    120

ttctttctgt gtttgttctc tgccctgcca aggccgtaga gctggtgcgt gcgggtagcg    180

gggctctccg aggagccgca cgccggcggc accatggtcc acctcactac tctcctctgc    240

aaggcctacc gtgggggcca cttaaccatc cgccttgccc tgggtggctg caccaatcgg    300

ccgttctacc gcattgtggc tgctcacaac aagtgtccca gggatggccg tttcgtagag    360

cagctgggct cctatgatcc attgcccaac agtcatggag aaaaactcgt tgccctcaac    420

ctagacagga tccgtcattg gattggctgc ggggcccacc tctctaagcc tatggaaaag    480

cttctgggtc ttgctggctt tttccctctg catcctatga tgatcacaaa tgctgagaga    540

ctgcgaagga aacgggcacg tgaagtcctg ttagcttctc agaaaacaga tgcagaagct    600

acagatacag aggctacaga aacataaatg agctgacttt agtgagcata gcagtgggaa    660

caaggtcaag gtccttttga aacactgcag cgatcttaat tttgttagat ttggagttca    720

ataaatggag tatcctgagt tgcccttgct cttctggcct ggcctgcaca gggcccaggg    780

agagatttgt tcttgtgtga cttagagctg ggtgtgggta ctaattagct tttttcgact    840

ttgtcttggg atagacagtg gctatgggag gattggactt ttgagttggg ctctgggtct    900

cttggacaac tttacaattt actggcttcc aagacttcct gcttcaaaac ccccagccag    960

actattcatg gcccattcag atcttcatgt tcatcccaca agtgcaagaa cagttaacct   1020

ttcttaattg atttttgtaa ttggaggttt atattgtctt gcctaatgca tattctcttt   1080

tttttttttt ttttgagacg gagtcttgtt ctgttgccag gctggagtgc ggtggtgcaa   1140

tctcagctca ctgcaatctc cacctcctgg gttcaagagg ttctcctgcc tcagcctcct   1200

gagtagccgg ggagctacaa gcatgcacca ccacacccag ctaatttttt tttttttttt   1260

gagaggagtc tcgctctgtc gcccaggctt gagtgcagtg gcgcgatctc ggctcactgc   1320

aagctctgtc tcctgggttc atgccattct cctgcttcag cctcccgagt agtcccagga   1380

gtagctggga ctacaggtgc ccaccaccac acccagctaa tttttttgta tttttagtag   1440

agatggggtt tcaccatgtt atccaggatg gttttgatct cctgacctcg tgatccgccc   1500

gccttggcct cccaaaagtg ctgggattat aggcgtgagc caccgcccgg gcaaattttt   1560

gtatttttag tagagatggg gtttcaccgt gttggccagg atggtctcaa tctgaccttg   1620

tgatctgccc acctcggcct cccaaagtgc taggattact ggcgtgagcc accactccta   1680

gccttaatgc atattcttaa atatacaaag gtagatttgt tatgaaaatt gctttggggc   1740

tctaataacc taccttttaa gaatgagaaa ctgctgggct taagggagtt cagtatgaat   1800

caagattgaa ccattcaaat gtggctgtga tttctgcata tatcatagat gggatccttc   1860

tgagaatact ggaataggga attaggacac caagccaatt cagctgtgaa ccttattctt   1920

gtacttttct ttcttgctgg taattttatg gagcaggtta agaaggctgc tctgtgttag   1980

gataaactgt ataccaataa tgttgacaac ctgtaatgag tgttgcattt tacttcttgt   2040

atcttttcct tcctaccttg atgccagtaa tctataaggg atctttatag tttgaatgta   2100

tttgaataac ttcagtatac tttagttcta cttttttatt tgactcacaa ccattcttag   2160

gtctcaagta ttcccatgtg ttttaaaagc ctgaagtcag tgagatgaaa ttcaacatca   2220

agaatttgaa gtaacttgta aggaaaaata atataaagat accattgggg cagtggctca   2280

cacctgtaat ctcagcactt tgggaggctg aggtggaagg atcacttgaa gccagagttt   2340

gagaccagcc tgtgcaacac agcaagaccc cgtctctaca aaaacttaaa aaattagctg   2400

gctgtggtgt tgctcaccca tagttccagc tactcgggaa gctgaggcag taagatcact   2460

tgagcccagg aggccgatgc tgcagtgaac tgtgattgtt ccactacagt ccagcctggg   2520

tgacagagaa aagaaaaaga aaacattaca taatttggct agagcataat aatttgattt   2580

tctggttttt gaaaatttga gttgcaataa aaggatattt cagtgtgcga tttc         2634


<210>  6991
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  6991

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Leu Ala Gly Phe 
                85                  90                  95


Phe Pro Leu His Pro Met Met Ile Thr Asn Ala Glu Arg Leu Arg Arg 
            100                 105                 110


Lys Arg Ala Arg Glu Val Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu 
        115                 120                 125


Ala Thr Asp Thr Glu Ala Thr Glu Thr 
    130                 135


<210>  6992
<211>  1655
<212>  DNA
<213>  Homo sapiens

<400>  6992
cgcacactga aatatccttt tattgcaact caaattttca aaaaccagaa aatcaaatta     60

ttatgctcta gccaaattat gtaatgtttt ctttttcttt tctctgtcac ccaggctgga    120

ctgtagtgga acaatcacag ttcactgcag catcggcctc ctgggctcaa gtgatcttac    180

tgcctcagct tcccgagtag ctggaactat gggtgagcaa caccacagcc agctaatttt    240

ttaagttttt gtagagacgg ggtcttgctg tgttgcacag gctggtctca aactctggct    300

tcaagtgatc cttccacctc agcctcccaa agtgctgaga ttacaggtgt gagccactgc    360

cccaatggta tctttatatt atttttcctt acaagttact tcaaattctt gatgttgaat    420

ttcatctcac tgacttcagg cttttaaaac acatgggaat acttgagacc taagaatggt    480

tgtgagtcaa ataaaaaagt agaactaaag tatactgaag ttattcaaat acattcaaac    540

tataaagatc ccttatagat tactggcatc aaggtaggaa ggaaaagata caagaagtaa    600

aatgcaacac tcattacagg ttgtcaacat tattggtata cagtttatcc taacacagag    660

cagccttctt aacctgctcc ataaaattac cagcaagaaa gaaaagtaca agaataaggt    720

tcacagctga attggcttgg tgtcctaatt ccctattcca gtattctcag aaggatccca    780

tctatgatat atgcagaaat cacagccaca tttgaatggt tcaatcttga ttcatactga    840

actcccttaa gcccagcagt ttctcattct taaaaggtag gttattagag ccccaaagca    900

attttcataa caaatctacc tttgtatatt taagaatatg cattaaggct aggagtggtg    960

catgcttgta gctccccggc tactcaggag gctgaggcag gagaacctct tgaacccagg   1020

aggtggagat tgcagtgagc tgagattgca ccaccgcact ccagcctggc aacagaacaa   1080

gactccgtct caaaaaaaaa aaaaaaaaga gaatatgcat taggcaagac aatataaacc   1140

tccaattaca aaaatcaatt aagaaaggtt aactgttctt gcacttgtgg gatgaacatg   1200

aagatctgaa tgggccatga atagtctggc tgggggtttt gaagcaggaa gtcttggaag   1260

ccagtaaatt gtaaagttgt ccaagagacc cagagcccaa ctcaaaagtc caatcctccc   1320

atagccactg tctatcccaa gacaaagtcg aaaaaagcta attagtaccc acacccagct   1380

ctaagtcaca caagaacaaa tctctccctg ggccctgtgc aggccaggcc agaagagcaa   1440

gggcaactca ggatactcca tttattgaac tccaaatcta acaaaattaa gatcgctgca   1500

gtgtttcaaa aggaccttga ccttgttccc actgctatgc tcactaaagt cagctcattt   1560

atgtttctgt agcctctgta tctgtagctt ctgcatctgt tttctgagaa gctaacagga   1620

cttcacgtgc ccgtttcctt cgcagtctct cagca                              1655


<210>  6993
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  6993

Met Leu Val Ala Pro Arg Leu Leu Arg Arg Leu Arg Gln Glu Asn Leu 
1               5                   10                  15


Leu Asn Pro Gly Gly Gly Asp Cys Ser Glu Leu Arg Leu His His Arg 
            20                  25                  30


Thr Pro Ala Trp Gln Gln Asn Lys Thr Pro Ser Gln Lys Lys Lys Lys 
        35                  40                  45


Lys Glu Asn Met His 
    50


<210>  6994
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  6994
ggggagagct ctcccaggcg cgatggaggc aacccgaacc tgaagcagcc acactgcctt     60

acatttgatc cttctctcag ttttttcccc acttaatcac cgctgaaaaa tttccacccc    120

attgaagcag ctaaggctcc gacaagctac tctcctctgc aaggcctacc gtgggggcca    180

cttaaccatc cgccttgccc tgggtggctg caccaatcgg ccgttctacc gcattgtggc    240

tgctcacaac aagtgtccca gggatggccg tttcgtagag cagctgggct cctatgatcc    300

attgcccaac agtcatggag aaaaactcgt tgccctcaac ctagacagga tccgtcattg    360

gattggctgc ggggcccacc tctctaagcc tatggaaaag cttctgggtc ttgctggctt    420

tttccctctg catcctatga tgatcacaaa tgctgagaga ctgcgaagga aacgggcacg    480

tgaagtcctg ttagcttctc agaaaacaga tgcagaagct acagatacag aggctacaga    540

aacataaatg agctgacttt agtgagcata gcagtgggaa caaggtcaag gtccttttga    600

aacactgcag cgatcttaat tttgttagat ttggagttca ataaatggag tatcctg       657


<210>  6995
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  6995

Met Glu Lys Leu Leu Gly Leu Ala Gly Phe Phe Pro Leu His Pro Met 
1               5                   10                  15


Met Ile Thr Asn Ala Glu Arg Leu Arg Arg Lys Arg Ala Arg Glu Val 
            20                  25                  30


Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu Ala Thr Asp Thr Glu Ala 
        35                  40                  45


Thr Glu Thr 
    50


<210>  6996
<211>  737
<212>  DNA
<213>  Homo sapiens

<400>  6996
gcattgtggg aagtataggg cggcaagcgg aggaggcgtg gcgagcggat catccgcttc     60

cggagtcgag gttttcgggc ttgtaccgct tggcggtgcg gcctggtgtc ggcttgcagg    120

ttctttctgt gtttgttctc tgccctgcca aggccgtaga gctggtgcgt gcgggtagcg    180

gggctctccg aggagccgca cgccggcggc accatggtcc acctcactac tctcctctgc    240

aaggcctacc gtgggggcca cttaaccatc cgccttgccc tgggtggctg caccaatcgg    300

ccgttctacc gcattgtggc tgctcacaac aagtgtccca gggatggccg tttcgtagag    360

cagctgggct cctatgatcc attgcccaac agtcatggag aaaaactcgt tgccctcaac    420

ctagacagga tccgtcattg gattggctgc ggggcccacc tctctaagcc tatggaaaag    480

cttctgggtc ttgctggctt tttccctctg catcctatga tgatcacaaa tgctgagaga    540

ctgcgaagga aacgggcacg tgaagtcctg ttagcttctc agaaaacaga tgcagaagct    600

acagatacag aggctacaga aacataaatg agctgacttt agtgagcata gcagtgggaa    660

caaggtcaag gtccttttga aacactgcag cgatcttaat tttgttagat ttggagttca    720

ataaatggag tatcctg                                                   737


<210>  6997
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  6997

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Leu Ala Gly Phe 
                85                  90                  95


Phe Pro Leu His Pro Met Met Ile Thr Asn Ala Glu Arg Leu Arg Arg 
            100                 105                 110


Lys Arg Ala Arg Glu Val Leu Leu Ala Ser Gln Lys Thr Asp Ala Glu 
        115                 120                 125


Ala Thr Asp Thr Glu Ala Thr Glu Thr 
    130                 135


<210>  6998
<211>  588
<212>  DNA
<213>  Homo sapiens

<400>  6998
attgtgggaa gtatagggcg gcaagcggag gaggcgtggc gagcggatca tccgcttccg     60

gagtcgaggt tttcgggctt gtaccgcttg gcggtgcggc ctggtgtcgg cttgcaggtt    120

ctttctgtgt ttgttctctg ccctgccaag gccgtagagc tggtgcgtgc gggtagcggg    180

gctctccgag gagccgcacg ccggcggcac catggtccac ctcactactc tcctctgcaa    240

ggcctaccgt gggggccact taaccatccg ccttgccctg ggtggctgca ccaatcggcc    300

gttctaccgc attgtggctg ctcacaacaa gtgtcccagg gatggccgtt tcgtagagca    360

gctgggctcc tatgatccat tgcccaacag tcatggagaa aaactcgttg ccctcaacct    420

agacaggatc cgtcattgga ttggctgcgg ggcccacctc tctaagccta tggaaaagct    480

tctgggtaac tcagctctgg tcttacctta ttgaggggat tttaaactga agtcagctcc    540

aggacagtag gtgtaagaat gattttcggc tgggcacggt ggctcacg                 588


<210>  6999
<211>  100
<212>  PRT
<213>  Homo sapiens

<400>  6999

Met Val His Leu Thr Thr Leu Leu Cys Lys Ala Tyr Arg Gly Gly His 
1               5                   10                  15


Leu Thr Ile Arg Leu Ala Leu Gly Gly Cys Thr Asn Arg Pro Phe Tyr 
            20                  25                  30


Arg Ile Val Ala Ala His Asn Lys Cys Pro Arg Asp Gly Arg Phe Val 
        35                  40                  45


Glu Gln Leu Gly Ser Tyr Asp Pro Leu Pro Asn Ser His Gly Glu Lys 
    50                  55                  60


Leu Val Ala Leu Asn Leu Asp Arg Ile Arg His Trp Ile Gly Cys Gly 
65                  70                  75                  80


Ala His Leu Ser Lys Pro Met Glu Lys Leu Leu Gly Asn Ser Ala Leu 
                85                  90                  95


Val Leu Pro Tyr 
            100


<210>  7000
<211>  784
<212>  DNA
<213>  Homo sapiens

<400>  7000
gtgcgatccc tctcagactt gtgagtccct gctggagtca gaagttttag gcgaatccca     60

ggcgcgccaa ggaaagtgct acaaaagcca tccatcttgc aagcgttggt gccgaggcgc    120

aacgctgaga acgcaaatac taaagggcgc tgttctttcc tcgtggagct cacagtccgc    180

tggggagacc gtgagatgac agcagagaaa ctagcgcgat cagtagtact cagcgcaagg    240

acagcgagca gagaaggcaa acctagtgct tgctaaggaa gacttcacag aggaggtagt    300

gtcagggccg agactaggag aaggattctc caggcttcat acggtaaaac tctctgggaa    360

ggaaaggaac tcagagtccc atgcagaaaa ttgttcagct ggaggggtat cagaaagatg    420

gatttccaaa gccaactgtt tcctgtagtg tgtggatctc tgcaagcaga gcctcatctt    480

tcaatttcag ctacatgaaa gaggaagaaa gggaaagata tatgtcatac gtgatatact    540

ttatgtggct ttgaagaccc ctcttttgtg gggctacggc taaagaacat agttccctgg    600

gatggaattg gctcttccta tttccctact tcatgaaaac tccagtagaa gaccttagaa    660

ccttgtcctg gttacatgga tatgtttact ttgtgaaaat tcatcaagca ctatgcacgg    720

tcatgatttg tacatttttt tgtaagataa cttcattaaa atttactttt tttattttta    780

aaaa                                                                 784


<210>  7001
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  7001

Met Gln Lys Ile Val Gln Leu Glu Gly Tyr Gln Lys Asp Gly Phe Pro 
1               5                   10                  15


Lys Pro Thr Val Ser Cys Ser Val Trp Ile Ser Ala Ser Arg Ala Ser 
            20                  25                  30


Ser Phe Asn Phe Ser Tyr Met Lys Glu Glu Glu Arg Glu Arg Tyr Met 
        35                  40                  45


Ser Tyr Val Ile Tyr Phe Met Trp Leu 
    50                  55


<210>  7002
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  7002
tagtgcttgc taaggaagac ttcacagagg agtcacacct taaaaaaaaa aggaggggtt     60

attcctgctt ttgccgtgct gtgatccagg gcagagctcc aggcttcata cggtaaaact    120

ctctgggaag gaaaggaact cagagtccca tgcagaaaat tgttcagctg gaggggtatc    180

agaaagatgg atttccaaag ccaactgttt cctgtagtgt gtggatctct gcaagcagag    240

cctcatcttt caatttcagc tacatgaaag aggaagaaag ggaaagatat atgtcatacg    300

tgatatactt tatgtggctt tgaagacccc tcttttgtgg ggctacggct aaagaacata    360

gttccctggg atggaattgg ctcttcctat ttccctactt catgaaaact ccagtagaag    420

accttagaac cttgtcctgg ttacatggat atgtttactt tgtgaaaatt catcaagcac    480

tatgcacggt catgatttgt acattttttt gtaagataac ttcattaaaa tttacttttt    540

ttatttttaa aaa                                                       553


<210>  7003
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  7003

Met Gln Lys Ile Val Gln Leu Glu Gly Tyr Gln Lys Asp Gly Phe Pro 
1               5                   10                  15


Lys Pro Thr Val Ser Cys Ser Val Trp Ile Ser Ala Ser Arg Ala Ser 
            20                  25                  30


Ser Phe Asn Phe Ser Tyr Met Lys Glu Glu Glu Arg Glu Arg Tyr Met 
        35                  40                  45


Ser Tyr Val Ile Tyr Phe Met Trp Leu 
    50                  55


<210>  7004
<211>  633
<212>  DNA
<213>  Homo sapiens

<400>  7004
cgtcccaccc ctatcgaggc agtcacacct taaaaaaaaa aggaggggtt attcctgctt     60

ttgccgtgct gtgatccagg gcagagtttc tcgtcaacca gtaaaacatc cagtaacaca    120

gccaatggaa ataaatgaat gggtctctgt ttatagtgaa gattctttcg ttctccagct    180

ccaggcttca tacggtaaaa ctctctggga aggaaaggaa ctcagagtcc catgcagaaa    240

attgttcagc tggaggggta tcagaaagat ggatttccaa agccaactgt ttcctgtagt    300

gtgtggatct ctgcaagcag agcctcatct ttcaatttca gctacatgaa agaggaagaa    360

agggaaagat atatgtcata cgtgatatac tttatgtggc tttgaagacc cctcttttgt    420

ggggctacgg ctaaagaaca tagttccctg ggatggaatt ggctcttcct atttccctac    480

ttcatgaaaa ctccagtaga agaccttaga accttgtcct ggttacatgg atatgtttac    540

tttgtgaaaa ttcatcaagc actatgcacg gtcatgattt gtacattttt ttgtaagata    600

acttcattaa aatttacttt ttttattttt aaa                                 633


<210>  7005
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  7005

Met Glu Ile Asn Glu Trp Val Ser Val Tyr Ser Glu Asp Ser Phe Val 
1               5                   10                  15


Leu Gln Leu Gln Ala Ser Tyr Gly Lys Thr Leu Trp Glu Gly Lys Glu 
            20                  25                  30


Leu Arg Val Pro Cys Arg Lys Leu Phe Ser Trp Arg Gly Ile Arg Lys 
        35                  40                  45


Met Asp Phe Gln Ser Gln Leu Phe Pro Val Val Cys Gly Ser Leu Gln 
    50                  55                  60


Ala Glu Pro His Leu Ser Ile Ser Ala Thr 
65                  70


<210>  7006
<211>  1713
<212>  DNA
<213>  Homo sapiens

<400>  7006
caggaggaac ttcagacatt tatcagtgag ctctatgtgt tcttagtaga tcagatgcat     60

gtagccctaa accagaccat gccagatgat gtccaaggca ctgttgcaac catttataca    120

agcagtgaac agcttcaact ctttgcattt gaagcagaag tcaatgagaa ctttgagatg    180

gcagcagcat attataaaga gagattggtc cgtgagcccc agaatctgga tcactggttg    240

gactatggtg ccttctgcct cctaactgaa gacaacatca aagcacaaga gtgttttcag    300

aaagcccttt ccctcaacca gagtcatatc cacagcttgt tgctgtgtgg tgtcctggct    360

gtcctgttgg agaactatga gcaagcagaa attttctttg aggatgctac ttgcttggaa    420

ccaactaatg ttgtagcctg gactttactt ggtttgtact atgaaattca aaacaatgat    480

attcgaatgg aaatggcatt tcatgaggcc tccaaacagc ttcaggcacg gatgcttcag    540

gcacaagtaa caaagcaaaa gagcactggt gtagaagaca ctgaggaaag agggaagaga    600

gaatctagtt taggcccttg gggaatcaca aatggttctg caacagcaat caaggtggaa    660

gccccagcag gaccaggagc tgcattatct attctagaca aatttcttga agaatcctcc    720

aaactgcagt ctgattcaca agaacccatt ttgactacac aaacttggga tccaagtata    780

agccaaaaac catctaacac atttatcaag gagataccaa caaagaaaga agcatcaaaa    840

tgtcaagatt catcagctct tctgcatccc ggccttcatt atggtgtttc tcaaactacc    900

accatcttca tggagaccat acatttcttg atgaaagtca aggctgtgca gtatgtgcac    960

agagtgcttg cacatgagct gttatgccct caaggaggcc ccagctgtga atattacttg   1020

gtgctggccc aaacacacat tcttaagaag aactttgcca aggcagagga ataccttcaa   1080

caagcagccc agatggacta cctgaacccc aatgtctggg gcctgaaggg ccatctctat   1140

tttctgagtg gaaatcattc tgaggccaag gcatgctatg aacgaaccat tagctttgta   1200

gtggatgctt ctgagatgca cttcatcttc ctgagactgg ggctcatcta tctggaagag   1260

aaagagctgg aggagctcac agaggctgag gatgctcttt ctgaagccaa tgcattgaac   1320

aactacaatg ctgaagtatg ggcatatctg gctctggtct gcctgaaagt tggacggcaa   1380

ttagaagctg agcaggccta caagtacatg atcaagctga aattgaaaga tgaggctctg   1440

cttgcagaga tccacacact acaggaaaca gttggctttg gaaatccatc tttctgatac   1500

ccctccagct gaacaatttt ctgcatggga ctctgagttc ctttccttcc cagagagttt   1560

taccgtatga agcctggagc tggagaacga aagaatcttc actataaaca gagacccatt   1620

catttatttc cattggctgt gttactggat gttttactgg ttgacgagaa actgggtcac   1680

aataaaaaaa tggagatatg aaactcaaaa ttc                                1713


<210>  7007
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  7007

Met His Val Ala Leu Asn Gln Thr Met Pro Asp Asp Val Gln Gly Thr 
1               5                   10                  15


Val Ala Thr Ile Tyr Thr Ser Ser Glu Gln Leu Gln Leu Phe Ala Phe 
            20                  25                  30


Glu Ala Glu Val Asn Glu Asn Phe Glu Met Ala Ala Ala Tyr Tyr Lys 
        35                  40                  45


Glu Arg Leu Val Arg Glu Pro Gln Asn Leu Asp His Trp Leu Asp Tyr 
    50                  55                  60


Gly Ala Phe Cys Leu Leu Thr Glu Asp Asn Ile Lys Ala Gln Glu Cys 
65                  70                  75                  80


Phe Gln Lys Ala Leu Ser Leu Asn Gln Ser His Ile His Ser Leu Leu 
                85                  90                  95


Leu Cys Gly Val Leu Ala Val Leu Leu Glu Asn Tyr Glu Gln Ala Glu 
            100                 105                 110


Ile Phe Phe Glu Asp Ala Thr Cys Leu Glu Pro Thr Asn Val Val Ala 
        115                 120                 125


Trp Thr Leu Leu Gly Leu Tyr Tyr Glu Ile Gln Asn Asn Asp Ile Arg 
    130                 135                 140


Met Glu Met Ala Phe His Glu Ala Ser Lys Gln Leu Gln Ala Arg Met 
145                 150                 155                 160


Leu Gln Ala Gln Val Thr Lys Gln Lys Ser Thr Gly Val Glu Asp Thr 
                165                 170                 175


Glu Glu Arg Gly Lys Arg Glu Ser Ser Leu Gly Pro Trp Gly Ile Thr 
            180                 185                 190


Asn Gly Ser Ala Thr Ala Ile Lys Val Glu Ala Pro Ala Gly Pro Gly 
        195                 200                 205


Ala Ala Leu Ser Ile Leu Asp Lys Phe Leu Glu Glu Ser Ser Lys Leu 
    210                 215                 220


Gln Ser Asp Ser Gln Glu Pro Ile Leu Thr Thr Gln Thr Trp Asp Pro 
225                 230                 235                 240


Ser Ile Ser Gln Lys Pro Ser Asn Thr Phe Ile Lys Glu Ile Pro Thr 
                245                 250                 255


Lys Lys Glu Ala Ser Lys Cys Gln Asp Ser Ser Ala Leu Leu His Pro 
            260                 265                 270


Gly Leu His Tyr Gly Val Ser Gln Thr Thr Thr Ile Phe Met Glu Thr 
        275                 280                 285


Ile His Phe Leu Met Lys Val Lys Ala Val Gln Tyr Val His Arg Val 
    290                 295                 300


Leu Ala His Glu Leu Leu Cys Pro Gln Gly Gly Pro Ser Cys Glu Tyr 
305                 310                 315                 320


Tyr Leu Val Leu Ala Gln Thr His Ile Leu Lys Lys Asn Phe Ala Lys 
                325                 330                 335


Ala Glu Glu Tyr Leu Gln Gln Ala Ala Gln Met Asp Tyr Leu Asn Pro 
            340                 345                 350


Asn Val Trp Gly Leu Lys Gly His Leu Tyr Phe Leu Ser Gly Asn His 
        355                 360                 365


Ser Glu Ala Lys Ala Cys Tyr Glu Arg Thr Ile Ser Phe Val Val Asp 
    370                 375                 380


Ala Ser Glu Met His Phe Ile Phe Leu Arg Leu Gly Leu Ile Tyr Leu 
385                 390                 395                 400


Glu Glu Lys Glu Leu Glu Glu Leu Thr Glu Ala Glu Asp Ala Leu Ser 
                405                 410                 415


Glu Ala Asn Ala Leu Asn Asn Tyr Asn Ala Glu Val Trp Ala Tyr Leu 
            420                 425                 430


Ala Leu Val Cys Leu Lys Val Gly Arg Gln Leu Glu Ala Glu Gln Ala 
        435                 440                 445


Tyr Lys Tyr Met Ile Lys Leu Lys Leu Lys Asp Glu Ala Leu Leu Ala 
    450                 455                 460


Glu Ile His Thr Leu Gln Glu Thr Val Gly Phe Gly Asn Pro Ser Phe 
465                 470                 475                 480


<210>  7008
<211>  3894
<212>  DNA
<213>  Homo sapiens

<400>  7008
gactcctgcc tgagtcatcc tcctcagtag ttgtcaaatg agaaatattg aaatcaaaga     60

gtcgagaaag caaaatgtaa aggtggaaac ctatgcactt aaacccaact cttggcaagg    120

taaagcatcc gcggaaacag caggctctcg aagtgaggag gctgcagccg gcgctagggc    180

gcaggcgcag aagctcagcg tctcgctccc tgctcccggc cccagagggt tatcgcgagt    240

cttggaataa acttgctcgt gcgatggcca aaaagaccaa agaaaacaga gggacttttc    300

ccagttggtg atatggagca agtgccatca gcaggcagac tcgtgcagat caccgtgaca    360

gagggatatg atttgaaagg ttttaaagga gatactccag ttacctttat tcgagcagaa    420

ttcaatcaag tggttctggg agactctgca aaaattactg tttctccaga aggaagtgca    480

aaatacaact tcactagcag ttttgagttt aatcctgaag gaggaatcac ttcagatgac    540

ctcgctcaca aacctgtgtt cttaactgtg actgaagttt taccaaagga aaagaaacag    600

aaagaagaga agaccttaat tcttggtcag gctgtggtgg accttcttcc cttactggaa    660

ggacagagtt catttcaaac aacagttcca ttgcaccctg tgcaaggctc acccttagaa    720

actcctagat caagtgctaa gcagtgcagt cttgaagtta aagtattagt ggcagagcct    780

ttactgacca cagcccagat ctcagggggc aatctactga aggtcacgtt ggaggctgct    840

tactctgtgc ctgaatcctt cattccaaca ggtcctgggc agaactacat ggtcggtctg    900

caagttccat cacttggaga gaaggactat cccattttat ttaagaatgg aactctgaag    960

cttggagggg aaagggaacc tgttccccgg cccaaaaagt ggccaattgc caacattctg   1020

gctccaggag ctaataacat tcctgatgca ttcattgttg gtggtcccta tgaagaagaa   1080

gaaggagaac tcaaccatcc tgaggacagc gaatttagga atcaagcaga gtgcataaag   1140

aaaaggatta tttgggactt ggaaagtcgc tgctaccttg atccttctgc agtggtcagt   1200

tttcagaagc gaattgccga ttgccggctt tggcctgtag agatcacaag agttcctctg   1260

gtcactatac ccaaagggaa agctggcaaa actgaaaaga ctgatgaaga agctcagctt   1320

tcgtttcatg gtgtggctta tgttaatatg gtcccattgt tgtatccagg tgtgaagaga   1380

attcggggag cttttcatgt ttacccttac ctagacagtg tagtccatga aaagaccaaa   1440

tgtttattga gcttgttccg ggatattggc catcacttga ttcataataa taaaatagga   1500

ggaattaatt ctctgctgtc caaacaagct gtttctaaga atctgaaaga agataaacca   1560

gtgaaagaaa aggatataga tggaaggcct aggcctgggg atgtgcaggc acctagtata   1620

aaatctcaga gctcagatac tcctttggaa ggtgaacccc ctctaagtca caatcctgaa   1680

ggacagcaat atgtagaagc agggacatac attgtgttgg aaattcagct ggacaaagcc   1740

ttggttccaa agcgaatgcc agaggagcta gccagaaggg tcaaggaaat gattcctcca   1800

aggcctcctc ttacccgtcg gacaggagga gctcagaagg caatgagtga ctaccacata   1860

cagatcaaga atatttctag agccattcta gatgaatact acagaatgtt tggaaaacag   1920

gtggccaaac tggagagtga tatggatagt gaaaccttgg aggagcagaa gtgccagctc   1980

agctatgaac ttaattgctc tggaaaatac tttgctttca aagaacaact caagcatgct   2040

gtggtaaaga ttgtgagaga taaatacttg aagacaacat catttgaaag ccaggaggaa   2100

cttcagacat ttatcagtga gctctatgtg ttcttagtag atcagatgca tgtagcccta   2160

aaccagacca tgccagatga tgtccaaggc actgttgcaa ccatttatac aagcagtgaa   2220

cagcttcaac tctttgcatt tgaagcagaa gtcaatgaga actttgagat ggcagcagca   2280

tattataaag agagattggt ccgtgagccc cagaatctgg atcactggtt ggactatggt   2340

gccttctgcc tcctaactga agacaacatc aaagcacaag agtgttttca gaaagccctt   2400

tccctcaacc agagtcatat ccacagcttg ttgctgtgtg gtgtcctggc tgtcctgttg   2460

gagaactatg agcaagcaga aattttcttt gaggatgcta cttgcttgga accaactaat   2520

gttgtagcct ggactttact tggtttgtac tatgaaattc aaaacaatga tattcgaatg   2580

gaaatggcat ttcatgaggc ctccaaacag cttcaggcac ggatgcttca ggcacaagta   2640

acaaagcaaa agagcactgg tgtagaagac actgaggaaa gagggaagag agaatctagt   2700

ttaggccctt ggggaatcac aaatggttct gcaacagcaa tcaaggtgga agccccagca   2760

ggaccaggag ctgcattatc tattctagac aaatttcttg aagaatcctc caaactgcag   2820

tctgattcac aagaacccat tttgactaca caaacttggg atccaagtat aagccaaaaa   2880

ccatctaaca catttatcaa ggagatacca acaaagaaag aagcatcaaa atgtcaagat   2940

tcatcagctc ttctgcatcc cggccttcat tatggtgttt ctcaaactac caccatcttc   3000

atggagacca tacatttctt gatgaaagtc aaggctgtgc agtatgtgca cagagtgctt   3060

gcacatgagc tgttatgccc tcaaggaggc cccagctgtg aatattactt ggtgctggcc   3120

caaacacaca ttcttaagaa gaactttgcc aaggcagagg aataccttca acaagcagcc   3180

cagatggact acctgaaccc caatgtctgg ggcctgaagg gccatctcta ttttctgagt   3240

ggaaatcatt ctgaggccaa ggcatgctat gaacgaacca ttagctttgt agtggatgct   3300

tctgagatgc acttcatctt cctgagactg gggctcatct atctggaaga gaaagagtat   3360

gaaaaggcaa agaaaaccta tatgcaagcc tgtaagagat caccttcatg ccttacctgg   3420

ctaggactgg gaatcgcctg ctatcggctg gaggagctca cagaggctga ggatgctctt   3480

tctgaagcca atgcattgaa caactacaat gctgaagtat gggcatatct ggctctggtc   3540

tgcctgaaag ttggacggca attagaagct gagcaggcct acaagtacat gatcaagctg   3600

aaattgaaag atgaggctct gcttgcagag atccacacac tacaggaaac agttggcttt   3660

ggaaatccat ctttctgata cccctccagc tgaacaattt tctgcatggg actctgagtt   3720

cctttccttc ccagagagtt ttaccgtatg aagcctggag ctggagaacg aaagaatctt   3780

cactataaac agagacccat tcatttattt ccattggctg tgttactgga tgttttactg   3840

gttgacgaga aactgggtca caataaaaaa atggagatat gaaactcaaa attc         3894


<210>  7009
<211>  1121
<212>  PRT
<213>  Homo sapiens

<400>  7009

Met Glu Gln Val Pro Ser Ala Gly Arg Leu Val Gln Ile Thr Val Thr 
1               5                   10                  15


Glu Gly Tyr Asp Leu Lys Gly Phe Lys Gly Asp Thr Pro Val Thr Phe 
            20                  25                  30


Ile Arg Ala Glu Phe Asn Gln Val Val Leu Gly Asp Ser Ala Lys Ile 
        35                  40                  45


Thr Val Ser Pro Glu Gly Ser Ala Lys Tyr Asn Phe Thr Ser Ser Phe 
    50                  55                  60


Glu Phe Asn Pro Glu Gly Gly Ile Thr Ser Asp Asp Leu Ala His Lys 
65                  70                  75                  80


Pro Val Phe Leu Thr Val Thr Glu Val Leu Pro Lys Glu Lys Lys Gln 
                85                  90                  95


Lys Glu Glu Lys Thr Leu Ile Leu Gly Gln Ala Val Val Asp Leu Leu 
            100                 105                 110


Pro Leu Leu Glu Gly Gln Ser Ser Phe Gln Thr Thr Val Pro Leu His 
        115                 120                 125


Pro Val Gln Gly Ser Pro Leu Glu Thr Pro Arg Ser Ser Ala Lys Gln 
    130                 135                 140


Cys Ser Leu Glu Val Lys Val Leu Val Ala Glu Pro Leu Leu Thr Thr 
145                 150                 155                 160


Ala Gln Ile Ser Gly Gly Asn Leu Leu Lys Val Thr Leu Glu Ala Ala 
                165                 170                 175


Tyr Ser Val Pro Glu Ser Phe Ile Pro Thr Gly Pro Gly Gln Asn Tyr 
            180                 185                 190


Met Val Gly Leu Gln Val Pro Ser Leu Gly Glu Lys Asp Tyr Pro Ile 
        195                 200                 205


Leu Phe Lys Asn Gly Thr Leu Lys Leu Gly Gly Glu Arg Glu Pro Val 
    210                 215                 220


Pro Arg Pro Lys Lys Trp Pro Ile Ala Asn Ile Leu Ala Pro Gly Ala 
225                 230                 235                 240


Asn Asn Ile Pro Asp Ala Phe Ile Val Gly Gly Pro Tyr Glu Glu Glu 
                245                 250                 255


Glu Gly Glu Leu Asn His Pro Glu Asp Ser Glu Phe Arg Asn Gln Ala 
            260                 265                 270


Glu Cys Ile Lys Lys Arg Ile Ile Trp Asp Leu Glu Ser Arg Cys Tyr 
        275                 280                 285


Leu Asp Pro Ser Ala Val Val Ser Phe Gln Lys Arg Ile Ala Asp Cys 
    290                 295                 300


Arg Leu Trp Pro Val Glu Ile Thr Arg Val Pro Leu Val Thr Ile Pro 
305                 310                 315                 320


Lys Gly Lys Ala Gly Lys Thr Glu Lys Thr Asp Glu Glu Ala Gln Leu 
                325                 330                 335


Ser Phe His Gly Val Ala Tyr Val Asn Met Val Pro Leu Leu Tyr Pro 
            340                 345                 350


Gly Val Lys Arg Ile Arg Gly Ala Phe His Val Tyr Pro Tyr Leu Asp 
        355                 360                 365


Ser Val Val His Glu Lys Thr Lys Cys Leu Leu Ser Leu Phe Arg Asp 
    370                 375                 380


Ile Gly His His Leu Ile His Asn Asn Lys Ile Gly Gly Ile Asn Ser 
385                 390                 395                 400


Leu Leu Ser Lys Gln Ala Val Ser Lys Asn Leu Lys Glu Asp Lys Pro 
                405                 410                 415


Val Lys Glu Lys Asp Ile Asp Gly Arg Pro Arg Pro Gly Asp Val Gln 
            420                 425                 430


Ala Pro Ser Ile Lys Ser Gln Ser Ser Asp Thr Pro Leu Glu Gly Glu 
        435                 440                 445


Pro Pro Leu Ser His Asn Pro Glu Gly Gln Gln Tyr Val Glu Ala Gly 
    450                 455                 460


Thr Tyr Ile Val Leu Glu Ile Gln Leu Asp Lys Ala Leu Val Pro Lys 
465                 470                 475                 480


Arg Met Pro Glu Glu Leu Ala Arg Arg Val Lys Glu Met Ile Pro Pro 
                485                 490                 495


Arg Pro Pro Leu Thr Arg Arg Thr Gly Gly Ala Gln Lys Ala Met Ser 
            500                 505                 510


Asp Tyr His Ile Gln Ile Lys Asn Ile Ser Arg Ala Ile Leu Asp Glu 
        515                 520                 525


Tyr Tyr Arg Met Phe Gly Lys Gln Val Ala Lys Leu Glu Ser Asp Met 
    530                 535                 540


Asp Ser Glu Thr Leu Glu Glu Gln Lys Cys Gln Leu Ser Tyr Glu Leu 
545                 550                 555                 560


Asn Cys Ser Gly Lys Tyr Phe Ala Phe Lys Glu Gln Leu Lys His Ala 
                565                 570                 575


Val Val Lys Ile Val Arg Asp Lys Tyr Leu Lys Thr Thr Ser Phe Glu 
            580                 585                 590


Ser Gln Glu Glu Leu Gln Thr Phe Ile Ser Glu Leu Tyr Val Phe Leu 
        595                 600                 605


Val Asp Gln Met His Val Ala Leu Asn Gln Thr Met Pro Asp Asp Val 
    610                 615                 620


Gln Gly Thr Val Ala Thr Ile Tyr Thr Ser Ser Glu Gln Leu Gln Leu 
625                 630                 635                 640


Phe Ala Phe Glu Ala Glu Val Asn Glu Asn Phe Glu Met Ala Ala Ala 
                645                 650                 655


Tyr Tyr Lys Glu Arg Leu Val Arg Glu Pro Gln Asn Leu Asp His Trp 
            660                 665                 670


Leu Asp Tyr Gly Ala Phe Cys Leu Leu Thr Glu Asp Asn Ile Lys Ala 
        675                 680                 685


Gln Glu Cys Phe Gln Lys Ala Leu Ser Leu Asn Gln Ser His Ile His 
    690                 695                 700


Ser Leu Leu Leu Cys Gly Val Leu Ala Val Leu Leu Glu Asn Tyr Glu 
705                 710                 715                 720


Gln Ala Glu Ile Phe Phe Glu Asp Ala Thr Cys Leu Glu Pro Thr Asn 
                725                 730                 735


Val Val Ala Trp Thr Leu Leu Gly Leu Tyr Tyr Glu Ile Gln Asn Asn 
            740                 745                 750


Asp Ile Arg Met Glu Met Ala Phe His Glu Ala Ser Lys Gln Leu Gln 
        755                 760                 765


Ala Arg Met Leu Gln Ala Gln Val Thr Lys Gln Lys Ser Thr Gly Val 
    770                 775                 780


Glu Asp Thr Glu Glu Arg Gly Lys Arg Glu Ser Ser Leu Gly Pro Trp 
785                 790                 795                 800


Gly Ile Thr Asn Gly Ser Ala Thr Ala Ile Lys Val Glu Ala Pro Ala 
                805                 810                 815


Gly Pro Gly Ala Ala Leu Ser Ile Leu Asp Lys Phe Leu Glu Glu Ser 
            820                 825                 830


Ser Lys Leu Gln Ser Asp Ser Gln Glu Pro Ile Leu Thr Thr Gln Thr 
        835                 840                 845


Trp Asp Pro Ser Ile Ser Gln Lys Pro Ser Asn Thr Phe Ile Lys Glu 
    850                 855                 860


Ile Pro Thr Lys Lys Glu Ala Ser Lys Cys Gln Asp Ser Ser Ala Leu 
865                 870                 875                 880


Leu His Pro Gly Leu His Tyr Gly Val Ser Gln Thr Thr Thr Ile Phe 
                885                 890                 895


Met Glu Thr Ile His Phe Leu Met Lys Val Lys Ala Val Gln Tyr Val 
            900                 905                 910


His Arg Val Leu Ala His Glu Leu Leu Cys Pro Gln Gly Gly Pro Ser 
        915                 920                 925


Cys Glu Tyr Tyr Leu Val Leu Ala Gln Thr His Ile Leu Lys Lys Asn 
    930                 935                 940


Phe Ala Lys Ala Glu Glu Tyr Leu Gln Gln Ala Ala Gln Met Asp Tyr 
945                 950                 955                 960


Leu Asn Pro Asn Val Trp Gly Leu Lys Gly His Leu Tyr Phe Leu Ser 
                965                 970                 975


Gly Asn His Ser Glu Ala Lys Ala Cys Tyr Glu Arg Thr Ile Ser Phe 
            980                 985                 990


Val Val Asp Ala Ser Glu Met His Phe Ile Phe Leu Arg Leu Gly Leu 
        995                 1000                1005


Ile Tyr Leu Glu Glu Lys Glu Tyr Glu Lys Ala Lys Lys Thr Tyr Met 
    1010                1015                1020


Gln Ala Cys Lys Arg Ser Pro Ser Cys Leu Thr Trp Leu Gly Leu Gly 
1025                1030                1035                1040


Ile Ala Cys Tyr Arg Leu Glu Glu Leu Thr Glu Ala Glu Asp Ala Leu 
                1045                1050                1055


Ser Glu Ala Asn Ala Leu Asn Asn Tyr Asn Ala Glu Val Trp Ala Tyr 
            1060                1065                1070


Leu Ala Leu Val Cys Leu Lys Val Gly Arg Gln Leu Glu Ala Glu Gln 
        1075                1080                1085


Ala Tyr Lys Tyr Met Ile Lys Leu Lys Leu Lys Asp Glu Ala Leu Leu 
    1090                1095                1100


Ala Glu Ile His Thr Leu Gln Glu Thr Val Gly Phe Gly Asn Pro Ser 
1105                1110                1115                1120


Phe 



<210>  7010
<211>  5004
<212>  DNA
<213>  Homo sapiens

<400>  7010
ggttgctata gttgtcaaaa acataactga ggctgctgca gagaccaaag aaaacagagg     60

gacttttccc agttggtgat atggagcaag tgccatcagc aggcagactc gtgcagatca    120

ccgtgacaga gggatatgat ttgaaaggtt ttaaaggaga tactccagtt acctttattc    180

gagcagaatt caatcaagtg gttctgggag actctgcaaa aattactgtt tctccagaag    240

gaagtgcaaa atacaacttc actagcagtt ttgagtttaa tcctgaagga ggaatcactt    300

cagatgacct cgctcacaaa cctgtgttct taactgtgac tgaagtttta ccaaaggaaa    360

agaaacagaa agaagagaag accttaattc ttggtcaggc tgtggtggac cttcttccct    420

tactggaagc agtgcagtct tgaagttaaa gtattagtgg cagagccttt actgaccaca    480

gcccagatct cagggggcaa tctactgaag gtcacgttgg aggctgctta ctctgtgcct    540

gaatccttca ttccaacagg tcctgggcag aactacatgg tcggtctgca agttccatca    600

cttggagaga aggactatcc cattttattt aagaatggaa ctctgaagct tggaggggaa    660

agggaacctg ttccccggcc caaaaagtgg ccaattgcca acattctggc tccaggagct    720

aataacattc ctgatgcatt cattgttggt ggtccctatg aagaagaaga aggagaactc    780

aaccatcctg aggacagcga atttaggaat caagcagagt gcataaagaa aaggattatt    840

tgggacttgg aaagtcgctg ctaccttgat ccttctgcag tggtcagttt tcagaagcga    900

attgccgatt gccggctttg gcctgtagag atcacaagag ttcctctggt cactataccc    960

aaagggaaag ctggcaaaac tgaaaaggtg tgaagagaat tcggggagct tttcatgttt   1020

acccttacct agacagtgta gtccatgaaa agaccaaatg tttattgagc ttgttccggg   1080

atattggcca tcacttgatt cataataata aaataggagg aattaattct ctgctgtcca   1140

aacaagctgt ttctaagaat ctgaaagaag ataaaccagt gaaagaaaag gatatagatg   1200

gaaggcctag gcctggggat gtgcaggcac ctagtataaa atctcagagc tcagatactc   1260

ctttggaagg tgaaccccct ctaagtcaca atcctgaagg acagcaatat gtagaagcag   1320

ggacatacat tgtgttggaa attcagctgg acaaagcctt ggttccaaag cgaatgccag   1380

aggagctagc cagaagggtc aaggaaatga ttcctccaag gcctcctctt acccgtcgga   1440

caggaggagc tcagaaggca atgagtgact accacataca gatcaagaat atttctagag   1500

ccattctaga tgaatactac agaatgtttg gaaaacaggt ggccaaactg gagagtgata   1560

tggatagtga aaccttggag gagcagaagt gccagctcag ctatgaactt aattgctctg   1620

gaaaatactt tgctttcaaa gaacaactca agcatgctgt ggtaaagatt gtgagagata   1680

aatacttgaa gacaacatca tttgaaagcc aggaggaact tcagacattt atcagtgagc   1740

tctatgtgtt cttagtagat cagatgcatg tagccctaaa ccaggtaagt gtcaagaact   1800

gagagcactt tcttttctct gtagagcatc agagtcttct atgaataatt ccttccaact   1860

gcctaagcct aatcagttta agactaattt tggaaaaaaa caaggagata tgctctttca   1920

atttcctaga aaaataaatt tcacaacttt aaaaaatgtg atggaattgt caaaaataga   1980

ttaaatatgt tgcataaatt gtgaaatgaa aattatcatt ctatttattc tgtgaacagg   2040

tacaattctt aattttttat tgaatatcat aaaagcagag aaaaactttg agttttcaga   2100

tattataccc aaatgacagt gacacttcaa acatgccttt tctgtttgac tggtggtctg   2160

ctgtcccacc cacttttctg tttatatttg taagtcttcc atcttgcctt catttgctta   2220

tttttatttg tattcagggg tagtttattt gaaaccagtg acaaagtcac agtctttttg   2280

tcccctggta gtgtctaacc atctgtgcct cctcaaattc tttattctat ttgcttttcc   2340

cttccttgtt tttcttctct accaccatca cctcttgttt cactttgttc tgtctttctg   2400

gagaaggtag gacaggagtg tccagcatca aaggattaag agaacagtcc tgccttgggc   2460

atggatgatt tgatttgaaa agcaattgag agtggagcat gagaaatgac aaaactgtga   2520

tgttagttga ttattgcata ataaggagga aaaagtttaa gttaagttta agtttcaatg   2580

ggtaattgat gccattcagt acttcttggt tgatactaaa aagaaaagaa aaacattaac   2640

caggacatgg aatgcaatta tgagtaaatt tggtgggagg cagatggtac tgaattcgct   2700

tttgaacata ggctctagtg gggttttgcc ggattcaaat tatgatgaat tgagtaaatg   2760

agcaatcaag aaacagatga atataaattc aagttggatg acgaaggaaa aaactggaaa   2820

agtagtagct agaagtgtca gcagttttca gtgggctaag taacaaaaag gtggaagaca   2880

agacatggag tgttggttct gggagtggga tattagagta ttctgttttg ggtgtagaag   2940

tgcatcgctg cagggatttg ggggtcaaga taatcaaaac taaaaagaac aggacaaaag   3000

tattaatcaa tgatcagaaa ctctctttgg cctatctcaa atttggcttt actgtccaca   3060

tttcttagca attatcctta ttaaaatcac tgatattatt ttgacttcta attaaagaat   3120

tttgtggact ctttcttgac catagcttct gactcaggag attcctaatt acaccagacc   3180

tgctctccca atctttgtgt ataggatata ttctttttct ggttttcctc ctaccttttt   3240

gtttcctttg aaggatctat cagtctatat ttcctactaa aactatagat ttggcttcta   3300

aaggtttacc cttaatctcc tgttttcttc acatttaaag accctagcga gggcttgcca   3360

acctttttca tgtcatgaca caaaaaaatg atagtatttg tcatatacac tacagaaaat   3420

gaaggaagct gtttgaggtc agaggtgacc tgcataggga ctatgaatgc cctgagggtt   3480

gaggcagtta tttctgccct aagcaatttt tacttacttc catgagctca gactgttggt   3540

attcagatac ctgagcttct ccttcaccct tgacatttct ctcctggttc actcttattc   3600

ttttactttt ttggcaagac tgtcattata gacatcaatc agtaacattt tagacgtcat   3660

aactggatct cacatcggat ttatgcttat gaaacctctc tacttgtaat tgtttcattt   3720

ttgtctacct aacatcttga cattgacaag accatgccag atgatgtcca aggcactgtt   3780

gcaaccattt atacaagcag tgaacagctt caactctttg catttgaagc agaagtcaat   3840

gagaactttg agatggcagc agcatattat aaagagagat tggtccgtga gccccagaat   3900

ctggatcact ggttggacta tggtgccttc tgcctcctaa ctgaagacaa catcaaagca   3960

caagagtgtt ttcagaaagc cctttccctc aaccagagtc atatccacag cttgttgctg   4020

tgtggtgtcc tggctgtcct gttggagaac tatgagcaag cagaaatttt ctttgaggat   4080

gctacttgct tggaaccaac taatgttgta gcctggactt tacttggttt gtactatgaa   4140

attcaaaaca atgatattcg aatggaaatg gcatttcatg aggcctccaa acagcttcag   4200

gcacggatgc ttcaggcaca agtaacaaag caaaagagca ctggtgtaga agacactgag   4260

gaaagaggga agagagaatc tagtttaggc ccttggggaa tcacaaatgg ttctgcaaca   4320

gcaatcaagg tggaagcccc agcagtatgt gcacagagtg cttgcacatg agctgttatg   4380

ccctcaagga ggccccagct gtgaatatta cttggtgctg gcccaaacac acattcttaa   4440

gaagaacttt gccaaggcag aggaatacct tcaacaagca gcccagatgg actacctgaa   4500

ccccaatgtc tggggcctga agggccatct ctattttctg agtggaaatc attctgaggc   4560

caaggcatgc tatgaacgaa ccattagctt tgtagtggat gcttctgaga tgcacttcat   4620

cttcctgaga ctggggctca tctatctgga agagaaagag gttggacggc aattagaagc   4680

tgagcaggcc tacaagtaca tgatcaagct gaaattgaaa gatgaggctc tgcttgcaga   4740

gatccacaca ctacaggaaa cagttggctt tggaaatcca tctttctgat acccctccag   4800

ctgaacaatt ttctgcatgg gactctgagt tcctttcctt cccagagagt tttaccgtat   4860

gaagcctgga gctggagaac gaaagaatct tcactataaa cagagaccca ttcatttatt   4920

tccattggct gtgttactgg atgttttact ggttgacgag aaactgggtc acaataaaaa   4980

aatggagata tgaaactcaa aatt                                          5004


<210>  7011
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  7011

Met Pro Asp Asp Val Gln Gly Thr Val Ala Thr Ile Tyr Thr Ser Ser 
1               5                   10                  15


Glu Gln Leu Gln Leu Phe Ala Phe Glu Ala Glu Val Asn Glu Asn Phe 
            20                  25                  30


Glu Met Ala Ala Ala Tyr Tyr Lys Glu Arg Leu Val Arg Glu Pro Gln 
        35                  40                  45


Asn Leu Asp His Trp Leu Asp Tyr Gly Ala Phe Cys Leu Leu Thr Glu 
    50                  55                  60


Asp Asn Ile Lys Ala Gln Glu Cys Phe Gln Lys Ala Leu Ser Leu Asn 
65                  70                  75                  80


Gln Ser His Ile His Ser Leu Leu Leu Cys Gly Val Leu Ala Val Leu 
                85                  90                  95


Leu Glu Asn Tyr Glu Gln Ala Glu Ile Phe Phe Glu Asp Ala Thr Cys 
            100                 105                 110


Leu Glu Pro Thr Asn Val Val Ala Trp Thr Leu Leu Gly Leu Tyr Tyr 
        115                 120                 125


Glu Ile Gln Asn Asn Asp Ile Arg Met Glu Met Ala Phe His Glu Ala 
    130                 135                 140


Ser Lys Gln Leu Gln Ala Arg Met Leu Gln Ala Gln Val Thr Lys Gln 
145                 150                 155                 160


Lys Ser Thr Gly Val Glu Asp Thr Glu Glu Arg Gly Lys Arg Glu Ser 
                165                 170                 175


Ser Leu Gly Pro Trp Gly Ile Thr Asn Gly Ser Ala Thr Ala Ile Lys 
            180                 185                 190


Val Glu Ala Pro Ala Val Cys Ala Gln Ser Ala Cys Thr 
        195                 200                 205


<210>  7012
<211>  579
<212>  DNA
<213>  Homo sapiens

<400>  7012
ggttgctata gttgtcaaaa acataactga ggctgctgca gaaaggtttt aaaggagata     60

ctccagttac ctttattcga gcagaattca atcaagtggt tctgggagac tctgcaaaaa    120

ttactgtttc tccagaagga agtgcaaaat acaacttcac tagcagtttt gagtttaatc    180

ctgaaggagg aatcacttca gatgacctcg ctcacaaacc tgtgttctta actgtgactg    240

aagttttacc aaaggaaaag aaacagaaag aagagaagac cttaattctt ggtcaggctg    300

tggtggacct tcttccctta ctggaagcag tgcagtcttg aagttaaagt attagtggca    360

gagcctttac tgaccacagc ccagatctca gggggcaatc tactgaaggt cacgttggag    420

gctgcttact ctgtgcctga atccttcatt ccaacaggtc ctgggcagaa ctacatggtc    480

ggtctgcaag ttccatcact tggagagaag gactatccca ttttatttaa gaatggaact    540

ctgaagcttg gaggggaaag ggaacctgtt ccccggccc                           579


<210>  7013
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  7013

Met Val Gly Leu Gln Val Pro Ser Leu Gly Glu Lys Asp Tyr Pro Ile 
1               5                   10                  15


Leu Phe Lys Asn Gly Thr Leu Lys Leu Gly Gly Glu Arg Glu Pro Val 
            20                  25                  30


Pro Arg 



<210>  7014
<211>  576
<212>  DNA
<213>  Homo sapiens

<400>  7014
agttgtcaaa aacataactg aggctgctgc agagaccaaa gaaaacagaa gggatatgat     60

ttgaaaggtt ttaaaggaga tactccagtt acctttattc gagcagaatt caatcaagtg    120

gttctgggag actctgcaaa aattactgtt tctccagaag gaagtgcaaa atacaacttc    180

actagcagtt ttgagtttaa tcctgaagga ggaatcactt cagatgacct cgctcacaaa    240

cctgtgttct taactgtgac tgaagtttta ccaaaggaaa agaaacagaa agaagagaag    300

accttaattc ttggtcaggc tgtggtggac cttcttccct tactggaagc agtgcagtct    360

tgaagttaaa gtattagtgg cagagccttt actgaccaca gcccagatct cagggggcaa    420

tctactgaag gtcacgttgg aggctgctta ctctgtgcct gaatccttca ttccaacagg    480

tcctgggcag aactacatgg tcggtctgca agttccatca cttggagaga aggactatcc    540

cattttattt aagaatggaa ctctgaagct tggagg                              576


<210>  7015
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7015

Gly Cys Cys Arg Asp Gln Arg Lys Gln Lys Gly Tyr Asp Leu Lys Gly 
1               5                   10                  15


Phe Lys Gly Asp Thr Pro Val Thr Phe Ile Arg Ala Glu Phe Asn Gln 
            20                  25                  30


Val Val Leu Gly Asp Ser Ala Lys Ile Thr Val Ser Pro Glu Gly Ser 
        35                  40                  45


Ala Lys Tyr Asn Phe Thr Ser Ser Phe Glu Phe Asn Pro Glu Gly Gly 
    50                  55                  60


Ile Thr Ser Asp Asp Leu Ala His Lys Pro Val Phe Leu Thr Val Thr 
65                  70                  75                  80


Glu Val Leu Pro Lys Glu Lys Lys Gln Lys Glu Glu Lys Thr Leu Ile 
                85                  90                  95


Leu Gly Gln Ala Val Val Asp Leu Leu Pro Leu Leu Glu Ala Val Gln 
            100                 105                 110


Ser 



<210>  7016
<211>  1586
<212>  DNA
<213>  Homo sapiens

<400>  7016
ctttatgcag agttcaaggc ccagccctac cttttccagg gcatgagtag aggagtaact     60

tcctgagaaa gtgtgtgtga atccaaaggc aataatctgg gaaatttttt ggaaatcgtg    120

atgagaacca gagtataaac caccaaatgg ctcaggaaga tgctcagcgt ctctatcaag    180

ctggtgaggg gagactaggg accgatgaat cttgctttaa catgatcctt gccacaagaa    240

gctttcctca gctgagagct accatggagg cttattctag gatggctaat cgagacttgt    300

taagcagtgt gagccgtgag ttttccggat atgtagaaag tggtttgaag accatcttgc    360

agtgtgccct gaaccgccct gccttctttg ctgagaggct ctactatgct atgaaaggtg    420

ctggcacaga tgactccacc ctggtccgga ttgtggtcac tcgaagtgag attgaccttg    480

tacaaataaa acagatgttc gctcagatgt atcagaagac tctgggcaca atgattgcag    540

gtgacacgag tggagattac cgaagacttc ttctggctat tgtgggccag taggagggat    600

tttttttttt ttaatgaaaa aaaatttcta ttcatagctt atccttcaga gcaatgacct    660

gcatgcagca atatcaaaca tcagctaacc gaaagagctt tctgtcaagg accgtatcag    720

ggtaatgtgc ttggtttgca catgttgtta ttgccttaat tctaatttta ttttgttctc    780

tacatacaat caatgtaaag ccatatcaca atgatacagt aatattgcaa tgtttgtaaa    840

ccttcattct tactagtttc attctaatca agatgtcaaa ttgaataaaa atcacagcaa    900

tctctgattc tgtgtaataa tattgaataa ttttttagaa ggttactgaa agctctgcct    960

tccggaatcc ctctaagtct gcttgataga gtggatagtg tgttaaaact gtgtacttta   1020

aaaaaaaatt caacctttac atctagaata atttgcatct cattttgcct aaattggttc   1080

tgtattcata aacactttcc acatagaaaa tagattagta ttacctgtgg caccttttaa   1140

gaaagggtca aatgtttata tgcttaagat acatagccta cttttttttc gcagttgttt   1200

tcttttttta aattgagtta tgacaaataa aaaattgcat atatttaagg tgtacaatat   1260

ggtgttttga tatcagcatt ccttgtgtaa tgattccaca attaaggtca ggctaattac   1320

gtatctgtca ccttgacata gttaccattt tttcatgtgt ggtgaaaaca cttaagatct   1380

actaccttag caaattttaa gtgttcagta cattattaac tatagatact gtgctctaca   1440

ttaaacctct agcatttatt cgttttataa ctgaaagttt ataccctttg accaacatct   1500

ccccattttc cccacctctc acctggacaa ccaccactgt gtttaagttc agctatttta   1560

gattccacgt ataaatggta tacaat                                        1586


<210>  7017
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  7017

Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg 
1               5                   10                  15


Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser 
            20                  25                  30


Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn 
        35                  40                  45


Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu 
    50                  55                  60


Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe 
65                  70                  75                  80


Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp 
                85                  90                  95


Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val 
            100                 105                 110


Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr 
        115                 120                 125


Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala 
    130                 135                 140


Ile Val Gly Gln 
145


<210>  7018
<211>  2399
<212>  DNA
<213>  Homo sapiens

<400>  7018
gcccccggct ccatcttgcg ggagaccggg ttgggctgtg acgctgctgc tggggtcagc     60

ctgcaggtca ggagtcatct tttccccctt ctggtcagta tccttatcct agtggctttc    120

ctccaatggg aggaggtgcc tacccacaag tgccaagtag tggctaccca ggagctggag    180

gctaccctgc gcctggaggt tatccagccc ctggaggcta tcctggtgcc ccacagccag    240

ggggagctcc atcctatccc ggagttcctc caggccaagg atttggagtc ccaccaggtg    300

gagcaggctt ttctgggtat ccacagccac cttcacagtc ttatggaggt ggtccagcac    360

aggttccact acctggtggc tttcctggag gacagatgcc ttctcagtat cctggaggac    420

aacctactta ccctagtcag cctgccacag tgactcaggt cactcaagga actatccgac    480

cagctgccaa cttcgatgct ataagagatg cagaaattct tcgtaaggca atgaagggtt    540

ttgggacaga tgagcaggca attgtggatg tggtggccaa ccgttccaat gatcagaggc    600

aaaaaattaa agcagcattt aagacctcct atggcaagga tttaatcaaa gatctcaaat    660

cagagttaag tggaaatatg gaagaactga tcctggccct cttcatgcct cctacgtatt    720

acgatgcctg gagcttacgg aaagcaatgc agggagcagg aactcaggaa cgtgtattga    780

ttgagatttt gtgcacaaga acaaatcagg aaatccgaga aattgtcaga tgttatcagt    840

cagaatttgg acgagacctt gaaaaggaca ttaggtcaga tacatcagga cattttgaac    900

gtttacttgt gtccatgtgc cagggaaatc gtgatgagaa ccagagtata aaccaccaaa    960

tggctcagga agatgctcag cgtctctatc aagctggtga ggggagacta gggaccgatg   1020

aatcttgctt taacatgatc cttgccacaa gaagctttcc tcagctgaga gctaccatgg   1080

aggcttattc taggatggct aatcgagact tgttaagcag tgtgagccgt gagttttccg   1140

gatatgtaga aagtggtttg aagaccatct tgcagtgtgc cctgaaccgc cctgccttct   1200

ttgctgagag gctctactat gctatgaaag gtgctggcac agatgactcc accctggtcc   1260

ggattgtggt cactcgaagt gagattgacc ttgtacaaat aaaacagatg ttcgctcaga   1320

tgtatcagaa gactctgggc acaatgattg caggtgacac gagtggagat taccgaagac   1380

ttcttctggc tattgtgggc cagtaggagg gatttttttt tttttaatga aaaaaaattt   1440

ctattcatag cttatccttc agagcaatga cctgcatgca gcaatatcaa acatcagcta   1500

accgaaagag ctttctgtca aggaccgtat cagggtaatg tgcttggttt gcacatgttg   1560

ttattgcctt aattctaatt ttattttgtt ctctacatac aatcaatgta aagccatatc   1620

acaatgatac agtaatattg caatgtttgt aaaccttcat tcttactagt ttcattctaa   1680

tcaagatgtc aaattgaata aaaatcacag caatctctga ttctgtgtaa taatattgaa   1740

taatttttta gaaggttact gaaagctctg ccttccggaa tccctctaag tctgcttgat   1800

agagtggata gtgtgttaaa actgtgtact ttaaaaaaaa attcaacctt tacatctaga   1860

ataatttgca tctcattttg cctaaattgg ttctgtattc ataaacactt tccacataga   1920

aaatagatta gtattacctg tggcaccttt taagaaaggg tcaaatgttt atatgcttaa   1980

gatacatagc ctactttttt ttcgcagttg ttttcttttt ttaaattgag ttatgacaaa   2040

taaaaaattg catatattta aggtgtacaa tatggtgttt tgatatcagc attccttgtg   2100

taatgattcc acaattaagg tcaggctaat tacgtatctg tcaccttgac atagttacca   2160

ttttttcatg tgtggtgaaa acacttaaga tctactacct tagcaaattt taagtgttca   2220

gtacattatt aactatagat actgtgctct acattaaacc tctagcattt attcgtttta   2280

taactgaaag tttataccct ttgaccaaca tctccccatt ttccccacct ctcacctgga   2340

caaccaccac tgtgtttaag ttcagctatt ttagattcca cgtataaatg gtatacaat    2399


<210>  7019
<211>  426
<212>  PRT
<213>  Homo sapiens

<400>  7019

Met Gly Gly Gly Ala Tyr Pro Gln Val Pro Ser Ser Gly Tyr Pro Gly 
1               5                   10                  15


Ala Gly Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Ala Pro Gly Gly Tyr 
            20                  25                  30


Pro Gly Ala Pro Gln Pro Gly Gly Ala Pro Ser Tyr Pro Gly Val Pro 
        35                  40                  45


Pro Gly Gln Gly Phe Gly Val Pro Pro Gly Gly Ala Gly Phe Ser Gly 
    50                  55                  60


Tyr Pro Gln Pro Pro Ser Gln Ser Tyr Gly Gly Gly Pro Ala Gln Val 
65                  70                  75                  80


Pro Leu Pro Gly Gly Phe Pro Gly Gly Gln Met Pro Ser Gln Tyr Pro 
                85                  90                  95


Gly Gly Gln Pro Thr Tyr Pro Ser Gln Pro Ala Thr Val Thr Gln Val 
            100                 105                 110


Thr Gln Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp 
        115                 120                 125


Ala Glu Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln 
    130                 135                 140


Ala Ile Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys 
145                 150                 155                 160


Ile Lys Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp 
                165                 170                 175


Leu Lys Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu 
            180                 185                 190


Phe Met Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met 
        195                 200                 205


Gln Gly Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr 
    210                 215                 220


Arg Thr Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu 
225                 230                 235                 240


Phe Gly Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His 
                245                 250                 255


Phe Glu Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn 
            260                 265                 270


Gln Ser Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr 
        275                 280                 285


Gln Ala Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met 
    290                 295                 300


Ile Leu Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala 
305                 310                 315                 320


Tyr Ser Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu 
                325                 330                 335


Phe Ser Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala 
            340                 345                 350


Leu Asn Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys 
        355                 360                 365


Gly Ala Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg 
    370                 375                 380


Ser Glu Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr 
385                 390                 395                 400


Gln Lys Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr 
                405                 410                 415


Arg Arg Leu Leu Leu Ala Ile Val Gly Gln 
            420                 425


<210>  7020
<211>  2460
<212>  DNA
<213>  Homo sapiens

<400>  7020
gggcccgccc ccggctccat cttgcgggag accgggttgg gctgtgacgc tgctgctggg     60

gtcagaatgt catacccagg ctatccccca acaggctacc cacctttccc tggatatcct    120

cctgcaggtc aggagtcatc ttttccccct tctggtcagt atccttatcc tagtggcttt    180

cctccaatgg gaggaggtgc ctacccacaa gtgccaagta gtggctaccc aggagctgga    240

ggctaccctg cgcctggagg ttatccagcc cctggaggct atcctggtgc cccacagcca    300

gggggagctc catcctatcc cggagttcct ccaggccaag gatttggagt cccaccaggt    360

ggagcaggct tttctgggta tccacagcca ccttcacagt cttatggagg tggtccagca    420

caggttccac tacctggtgg ctttcctgga ggacagatgc cttctcagta tcctggagga    480

caacctactt accctagtca gcctgccaca gtgactcagg tcactcaagg aactatccga    540

ccagctgcca acttcgatgc tataagagat gcagaaattc ttcgtaaggc aatgaagggt    600

tttgggacag atgagcaggc aattgtggat gtggtggcca accgttccaa tgatcagagg    660

caaaaaatta aagcagcatt taagacctcc tatggcaagg atttaatcaa agatctcaaa    720

tcagagttaa gtggaaatat ggaagaactg atcctggccc tcttcatgcc tcctacgtat    780

tacgatgcct ggagcttacg gaaagcaatg cagggagcag gaactcagga acgtgtattg    840

attgagattt tgtgcacaag aacaaatcag gaaatccgag aaattgtcag atgttatcag    900

tcagaatttg gacgagacct tgaaaaggac attaggtcag atacatcagg acattttgaa    960

cgtttacttg tgtccatgtg ccagggaaat cgtgatgaga accagagtat aaaccaccaa   1020

atggctcagg aagatgctca gcgtctctat caagctggtg aggggagact agggaccgat   1080

gaatcttgct ttaacatgat ccttgccaca agaagctttc ctcagctgag agctaccatg   1140

gaggcttatt ctaggatggc taatcgagac ttgttaagca gtgtgagccg tgagttttcc   1200

ggatatgtag aaagtggttt gaagaccatc ttgcagtgtg ccctgaaccg ccctgccttc   1260

tttgctgaga ggctctacta tgctatgaaa ggtgctggca cagatgactc caccctggtc   1320

cggattgtgg tcactcgaag tgagattgac cttgtacaaa taaaacagat gttcgctcag   1380

atgtatcaga agactctggg cacaatgatt gcaggtgaca cgagtggaga ttaccgaaga   1440

cttcttctgg ctattgtggg ccagtaggag ggattttttt ttttttaatg aaaaaaaatt   1500

tctattcata gcttatcctt cagagcaatg acctgcatgc agcaatatca aacatcagct   1560

aaccgaaaga gctttctgtc aaggaccgta tcagggtaat gtgcttggtt tgcacatgtt   1620

gttattgcct taattctaat tttattttgt tctctacata caatcaatgt aaagccatat   1680

cacaatgata cagtaatatt gcaatgtttg taaaccttca ttcttactag tttcattcta   1740

atcaagatgt caaattgaat aaaaatcaca gcaatctctg attctgtgta ataatattga   1800

ataatttttt agaaggttac tgaaagctct gccttccgga atccctctaa gtctgcttga   1860

tagagtggat agtgtgttaa aactgtgtac tttaaaaaaa aattcaacct ttacatctag   1920

aataatttgc atctcatttt gcctaaattg gttctgtatt cataaacact ttccacatag   1980

aaaatagatt agtattacct gtggcacctt ttaagaaagg gtcaaatgtt tatatgctta   2040

agatacatag cctacttttt tttcgcagtt gttttctttt tttaaattga gttatgacaa   2100

ataaaaaatt gcatatattt aaggtgtaca atatggtgtt ttgatatcag cattccttgt   2160

gtaatgattc cacaattaag gtcaggctaa ttacgtatct gtcaccttga catagttacc   2220

attttttcat gtgtggtgaa aacacttaag atctactacc ttagcaaatt ttaagtgttc   2280

agtacattat taactataga tactgtgctc tacattaaac ctctagcatt tattcgtttt   2340

ataactgaaa gtttataccc tttgaccaac atctccccat tttccccacc tctcacctgg   2400

acaaccacca ctgtgtttaa gttcagctat tttagattcc acgtataaat ggtatacaat   2460


<210>  7021
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  7021

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Pro Ala Thr Val Thr Gln Val Thr Gln Gly Thr Ile Arg Pro Ala 
145                 150                 155                 160


Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu Ile Leu Arg Lys Ala Met 
                165                 170                 175


Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Val Asp Val Val Ala Asn 
            180                 185                 190


Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys Ala Ala Phe Lys Thr Ser 
        195                 200                 205


Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser Glu Leu Ser Gly Asn 
    210                 215                 220


Met Glu Glu Leu Ile Leu Ala Leu Phe Met Pro Pro Thr Tyr Tyr Asp 
225                 230                 235                 240


Ala Trp Ser Leu Arg Lys Ala Met Gln Gly Ala Gly Thr Gln Glu Arg 
                245                 250                 255


Val Leu Ile Glu Ile Leu Cys Thr Arg Thr Asn Gln Glu Ile Arg Glu 
            260                 265                 270


Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly Arg Asp Leu Glu Lys Asp 
        275                 280                 285


Ile Arg Ser Asp Thr Ser Gly His Phe Glu Arg Leu Leu Val Ser Met 
    290                 295                 300


Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser Ile Asn His Gln Met Ala 
305                 310                 315                 320


Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg Leu Gly 
                325                 330                 335


Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser Phe Pro 
            340                 345                 350


Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn Arg Asp 
        355                 360                 365


Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu Ser Gly 
    370                 375                 380


Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe Phe Ala 
385                 390                 395                 400


Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp Ser Thr 
                405                 410                 415


Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val Gln Ile 
            420                 425                 430


Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr Met Ile 
        435                 440                 445


Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala Ile Val 
    450                 455                 460


Gly Gln 
465


<210>  7022
<211>  2532
<212>  DNA
<213>  Homo sapiens

<400>  7022
caccctgggc ccgcccccgg ctccatcttg cgggagaccg ggttgggctg tgacgctgct     60

gctggggtca gaatgtcata cccaggctat cccccaacag gctacccacc tttccctgga    120

tatcctcctg caggtcagga gtcatctttt cccccttctg gtcagtatcc ttatcctagt    180

ggctttcctc caatgggagg aggtgcctac ccacaagtgc caagtagtgg ctacccagga    240

gctggaggct accctgcgcc tggaggttat ccagcccctg gaggctatcc tggtgcccca    300

cagccagggg gagctccatc ctatcccgga gttcctccag gccaaggatt tggagtccca    360

ccaggtggag caggcttttc tgggtatcca cagccacctt cacagtctta tggaggtggt    420

ccagcacagg ttccactacc tggtggcttt cctggaggac agatgccttc tcagtatcct    480

ggaggacaac ctacttaccc tagtcagatc aatacagatt ctttttcttc ctatcctgtt    540

ttctctcctg tttctttgga ttatagcagt gaacctgcca cagtgactca ggtcactcaa    600

ggaactatcc gaccagctgc caacttcgat gctataagag atgcagaaat tcttcgtaag    660

gcaatgaagg gttttgggac agatgagcag gcaattgtgg atgtggtggc caaccgttcc    720

aatgatcaga ggcaaaaaat taaagcagca tttaagacct cctatggcaa ggatttaatc    780

aaagatctca aatcagagtt aagtggaaat atggaagaac tgatcctggc cctcttcatg    840

cctcctacgt attacgatgc ctggagctta cggaaagcaa tgcagggagc aggaactcag    900

gaacgtgtat tgattgagat tttgtgcaca agaacaaatc aggaaatccg agaaattgtc    960

agatgttatc agtcagaatt tggacgagac cttgaaaagg acattaggtc agatacatca   1020

ggacattttg aacgtttact tgtgtccatg tgccagggaa atcgtgatga gaaccagagt   1080

ataaaccacc aaatggctca ggaagatgct cagcgtctct atcaagctgg tgaggggaga   1140

ctagggaccg atgaatcttg ctttaacatg atccttgcca caagaagctt tcctcagctg   1200

agagctacca tggaggctta ttctaggatg gctaatcgag acttgttaag cagtgtgagc   1260

cgtgagtttt ccggatatgt agaaagtggt ttgaagacca tcttgcagtg tgccctgaac   1320

cgccctgcct tctttgctga gaggctctac tatgctatga aaggtgctgg cacagatgac   1380

tccaccctgg tccggattgt ggtcactcga agtgagattg accttgtaca aataaaacag   1440

atgttcgctc agatgtatca gaagactctg ggcacaatga ttgcaggtga cacgagtgga   1500

gattaccgaa gacttcttct ggctattgtg ggccagtagg agggattttt ttttttttaa   1560

tgaaaaaaaa tttctattca tagcttatcc ttcagagcaa tgacctgcat gcagcaatat   1620

caaacatcag ctaaccgaaa gagctttctg tcaaggaccg tatcagggta atgtgcttgg   1680

tttgcacatg ttgttattgc cttaattcta attttatttt gttctctaca tacaatcaat   1740

gtaaagccat atcacaatga tacagtaata ttgcaatgtt tgtaaacctt cattcttact   1800

agtttcattc taatcaagat gtcaaattga ataaaaatca cagcaatctc tgattctgtg   1860

taataatatt gaataatttt ttagaaggtt actgaaagct ctgccttccg gaatccctct   1920

aagtctgctt gatagagtgg atagtgtgtt aaaactgtgt actttaaaaa aaaattcaac   1980

ctttacatct agaataattt gcatctcatt ttgcctaaat tggttctgta ttcataaaca   2040

ctttccacat agaaaataga ttagtattac ctgtggcacc ttttaagaaa gggtcaaatg   2100

tttatatgct taagatacat agcctacttt tttttcgcag ttgttttctt tttttaaatt   2160

gagttatgac aaataaaaaa ttgcatatat ttaaggtgta caatatggtg ttttgatatc   2220

agcattcctt gtgtaatgat tccacaatta aggtcaggct aattacgtat ctgtcacctt   2280

gacatagtta ccattttttc atgtgtggtg aaaacactta agatctacta ccttagcaaa   2340

ttttaagtgt tcagtacatt attaactata gatactgtgc tctacattaa acctctagca   2400

tttattcgtt ttataactga aagtttatac cctttgacca acatctcccc attttcccca   2460

cctctcacct ggacaaccac cactgtgttt aagttcagct attttagatt ccacgtataa   2520

atggtataca at                                                       2532


<210>  7023
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7023

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Ile Asn Thr Asp Ser Phe Ser Ser Tyr Pro Val Phe Ser Pro Val 
145                 150                 155                 160


Ser Leu Asp Tyr Ser Ser Glu Pro Ala Thr Val Thr Gln Val Thr Gln 
                165                 170                 175


Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu 
            180                 185                 190


Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile 
        195                 200                 205


Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys 
    210                 215                 220


Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys 
225                 230                 235                 240


Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu Phe Met 
                245                 250                 255


Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met Gln Gly 
            260                 265                 270


Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr Arg Thr 
        275                 280                 285


Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly 
    290                 295                 300


Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His Phe Glu 
305                 310                 315                 320


Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser 
                325                 330                 335


Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala 
            340                 345                 350


Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu 
        355                 360                 365


Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser 
    370                 375                 380


Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser 
385                 390                 395                 400


Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn 
                405                 410                 415


Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala 
            420                 425                 430


Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu 
        435                 440                 445


Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys 
    450                 455                 460


Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg 
465                 470                 475                 480


Leu Leu Leu Ala Ile Val Gly Gln 
                485


<210>  7024
<211>  1255
<212>  DNA
<213>  Homo sapiens

<400>  7024
ctttatgcag agttcaaggc ccagccctac cttttccagg gcatgagtag aggagtaact     60

tcctgagaaa gtgtgtgtga atccaaaggc aataatctgg gaaatttttt ggaaatcgtg    120

atgagaacca gagtataaac caccaaatgg ctcaggaaga tgctcagcgt ctctatcaag    180

ctggtgaggg gagactaggg accgatgaat cttgctttaa catgatcctt gccacaagaa    240

gctttcctca gctgagagct accatggagg cttattctag gatggctaat cgagacttgt    300

taagcagtgt gagccgtgag ttttccggat atgtagaaag tggtttgaag accatcttgc    360

agtgtgccct gaaccgccct gccttctttg ctgagaggct ctactatgct atgaaaggtg    420

ctggcacaga tgactccacc ctggtccgga ttgtggtcac tcgaagtgag attgaccttg    480

tacaaataaa acagatgttc gctcagatgt atcagaagac tctgggcaca atgattgcag    540

gtgacacgag tggagattac cgaagacttc ttctggctat tgtgggccag taggagggat    600

tttttttttt ttaatgaaaa aaaatttcta ttcatagctt atccttcaga gcaatgacct    660

gcatgcagca atatcaaaca tcagctaacc gaaagagctt tctgtcaagg accgtatcag    720

ggtaatgtgc ttggtttgca catgttgtta ttgccttaat tctaatttta ttttgttctc    780

tacatacaat caatgtaaag ccatatcaca atgatacagt aatattgcaa tgtttgtaaa    840

ccttcattct tactagtttc attctaatca agatgtcaaa ttgaataaaa atcacagcaa    900

tctctgattc tgtgtaataa tattgaataa ttttttagaa ggttactgaa agctctgcct    960

tccggaatcc ctctaagtct gcttgataga gtggatagtg tgttaaaact gtgtacttta   1020

aaaaaaaatt caacctttac atctagaata atttgcatct cattttgcct aaattggttc   1080

tgtattcata aacactttcc acatagaaaa tagattagta ttacctgtgg caccttttaa   1140

gaaagggtca aatgtttata tgcttaagat acatagccta cttttttttc gcagttgttt   1200

tcttttttta aattgagtta tgacaaataa aaaattgcat atatttaagg tgtac        1255


<210>  7025
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  7025

Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg 
1               5                   10                  15


Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser 
            20                  25                  30


Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn 
        35                  40                  45


Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu 
    50                  55                  60


Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe 
65                  70                  75                  80


Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp 
                85                  90                  95


Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val 
            100                 105                 110


Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr 
        115                 120                 125


Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala 
    130                 135                 140


Ile Val Gly Gln 
145


<210>  7026
<211>  2068
<212>  DNA
<213>  Homo sapiens

<400>  7026
gcccccggct ccatcttgcg ggagaccggg ttgggctgtg acgctgctgc tggggtcagc     60

ctgcaggtca ggagtcatct tttccccctt ctggtcagta tccttatcct agtggctttc    120

ctccaatggg aggaggtgcc tacccacaag tgccaagtag tggctaccca ggagctggag    180

gctaccctgc gcctggaggt tatccagccc ctggaggcta tcctggtgcc ccacagccag    240

ggggagctcc atcctatccc ggagttcctc caggccaagg atttggagtc ccaccaggtg    300

gagcaggctt ttctgggtat ccacagccac cttcacagtc ttatggaggt ggtccagcac    360

aggttccact acctggtggc tttcctggag gacagatgcc ttctcagtat cctggaggac    420

aacctactta ccctagtcag cctgccacag tgactcaggt cactcaagga actatccgac    480

cagctgccaa cttcgatgct ataagagatg cagaaattct tcgtaaggca atgaagggtt    540

ttgggacaga tgagcaggca attgtggatg tggtggccaa ccgttccaat gatcagaggc    600

aaaaaattaa agcagcattt aagacctcct atggcaagga tttaatcaaa gatctcaaat    660

cagagttaag tggaaatatg gaagaactga tcctggccct cttcatgcct cctacgtatt    720

acgatgcctg gagcttacgg aaagcaatgc agggagcagg aactcaggaa cgtgtattga    780

ttgagatttt gtgcacaaga acaaatcagg aaatccgaga aattgtcaga tgttatcagt    840

cagaatttgg acgagacctt gaaaaggaca ttaggtcaga tacatcagga cattttgaac    900

gtttacttgt gtccatgtgc cagggaaatc gtgatgagaa ccagagtata aaccaccaaa    960

tggctcagga agatgctcag cgtctctatc aagctggtga ggggagacta gggaccgatg   1020

aatcttgctt taacatgatc cttgccacaa gaagctttcc tcagctgaga gctaccatgg   1080

aggcttattc taggatggct aatcgagact tgttaagcag tgtgagccgt gagttttccg   1140

gatatgtaga aagtggtttg aagaccatct tgcagtgtgc cctgaaccgc cctgccttct   1200

ttgctgagag gctctactat gctatgaaag gtgctggcac agatgactcc accctggtcc   1260

ggattgtggt cactcgaagt gagattgacc ttgtacaaat aaaacagatg ttcgctcaga   1320

tgtatcagaa gactctgggc acaatgattg caggtgacac gagtggagat taccgaagac   1380

ttcttctggc tattgtgggc cagtaggagg gatttttttt tttttaatga aaaaaaattt   1440

ctattcatag cttatccttc agagcaatga cctgcatgca gcaatatcaa acatcagcta   1500

accgaaagag ctttctgtca aggaccgtat cagggtaatg tgcttggttt gcacatgttg   1560

ttattgcctt aattctaatt ttattttgtt ctctacatac aatcaatgta aagccatatc   1620

acaatgatac agtaatattg caatgtttgt aaaccttcat tcttactagt ttcattctaa   1680

tcaagatgtc aaattgaata aaaatcacag caatctctga ttctgtgtaa taatattgaa   1740

taatttttta gaaggttact gaaagctctg ccttccggaa tccctctaag tctgcttgat   1800

agagtggata gtgtgttaaa actgtgtact ttaaaaaaaa attcaacctt tacatctaga   1860

ataatttgca tctcattttg cctaaattgg ttctgtattc ataaacactt tccacataga   1920

aaatagatta gtattacctg tggcaccttt taagaaaggg tcaaatgttt atatgcttaa   1980

gatacatagc ctactttttt ttcgcagttg ttttcttttt ttaaattgag ttatgacaaa   2040

taaaaaattg catatattta aggtgtac                                      2068


<210>  7027
<211>  426
<212>  PRT
<213>  Homo sapiens

<400>  7027

Met Gly Gly Gly Ala Tyr Pro Gln Val Pro Ser Ser Gly Tyr Pro Gly 
1               5                   10                  15


Ala Gly Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Ala Pro Gly Gly Tyr 
            20                  25                  30


Pro Gly Ala Pro Gln Pro Gly Gly Ala Pro Ser Tyr Pro Gly Val Pro 
        35                  40                  45


Pro Gly Gln Gly Phe Gly Val Pro Pro Gly Gly Ala Gly Phe Ser Gly 
    50                  55                  60


Tyr Pro Gln Pro Pro Ser Gln Ser Tyr Gly Gly Gly Pro Ala Gln Val 
65                  70                  75                  80


Pro Leu Pro Gly Gly Phe Pro Gly Gly Gln Met Pro Ser Gln Tyr Pro 
                85                  90                  95


Gly Gly Gln Pro Thr Tyr Pro Ser Gln Pro Ala Thr Val Thr Gln Val 
            100                 105                 110


Thr Gln Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp 
        115                 120                 125


Ala Glu Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln 
    130                 135                 140


Ala Ile Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys 
145                 150                 155                 160


Ile Lys Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp 
                165                 170                 175


Leu Lys Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu 
            180                 185                 190


Phe Met Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met 
        195                 200                 205


Gln Gly Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr 
    210                 215                 220


Arg Thr Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu 
225                 230                 235                 240


Phe Gly Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His 
                245                 250                 255


Phe Glu Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn 
            260                 265                 270


Gln Ser Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr 
        275                 280                 285


Gln Ala Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met 
    290                 295                 300


Ile Leu Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala 
305                 310                 315                 320


Tyr Ser Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu 
                325                 330                 335


Phe Ser Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala 
            340                 345                 350


Leu Asn Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys 
        355                 360                 365


Gly Ala Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg 
    370                 375                 380


Ser Glu Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr 
385                 390                 395                 400


Gln Lys Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr 
                405                 410                 415


Arg Arg Leu Leu Leu Ala Ile Val Gly Gln 
            420                 425


<210>  7028
<211>  2129
<212>  DNA
<213>  Homo sapiens

<400>  7028
gggcccgccc ccggctccat cttgcgggag accgggttgg gctgtgacgc tgctgctggg     60

gtcagaatgt catacccagg ctatccccca acaggctacc cacctttccc tggatatcct    120

cctgcaggtc aggagtcatc ttttccccct tctggtcagt atccttatcc tagtggcttt    180

cctccaatgg gaggaggtgc ctacccacaa gtgccaagta gtggctaccc aggagctgga    240

ggctaccctg cgcctggagg ttatccagcc cctggaggct atcctggtgc cccacagcca    300

gggggagctc catcctatcc cggagttcct ccaggccaag gatttggagt cccaccaggt    360

ggagcaggct tttctgggta tccacagcca ccttcacagt cttatggagg tggtccagca    420

caggttccac tacctggtgg ctttcctgga ggacagatgc cttctcagta tcctggagga    480

caacctactt accctagtca gcctgccaca gtgactcagg tcactcaagg aactatccga    540

ccagctgcca acttcgatgc tataagagat gcagaaattc ttcgtaaggc aatgaagggt    600

tttgggacag atgagcaggc aattgtggat gtggtggcca accgttccaa tgatcagagg    660

caaaaaatta aagcagcatt taagacctcc tatggcaagg atttaatcaa agatctcaaa    720

tcagagttaa gtggaaatat ggaagaactg atcctggccc tcttcatgcc tcctacgtat    780

tacgatgcct ggagcttacg gaaagcaatg cagggagcag gaactcagga acgtgtattg    840

attgagattt tgtgcacaag aacaaatcag gaaatccgag aaattgtcag atgttatcag    900

tcagaatttg gacgagacct tgaaaaggac attaggtcag atacatcagg acattttgaa    960

cgtttacttg tgtccatgtg ccagggaaat cgtgatgaga accagagtat aaaccaccaa   1020

atggctcagg aagatgctca gcgtctctat caagctggtg aggggagact agggaccgat   1080

gaatcttgct ttaacatgat ccttgccaca agaagctttc ctcagctgag agctaccatg   1140

gaggcttatt ctaggatggc taatcgagac ttgttaagca gtgtgagccg tgagttttcc   1200

ggatatgtag aaagtggttt gaagaccatc ttgcagtgtg ccctgaaccg ccctgccttc   1260

tttgctgaga ggctctacta tgctatgaaa ggtgctggca cagatgactc caccctggtc   1320

cggattgtgg tcactcgaag tgagattgac cttgtacaaa taaaacagat gttcgctcag   1380

atgtatcaga agactctggg cacaatgatt gcaggtgaca cgagtggaga ttaccgaaga   1440

cttcttctgg ctattgtggg ccagtaggag ggattttttt ttttttaatg aaaaaaaatt   1500

tctattcata gcttatcctt cagagcaatg acctgcatgc agcaatatca aacatcagct   1560

aaccgaaaga gctttctgtc aaggaccgta tcagggtaat gtgcttggtt tgcacatgtt   1620

gttattgcct taattctaat tttattttgt tctctacata caatcaatgt aaagccatat   1680

cacaatgata cagtaatatt gcaatgtttg taaaccttca ttcttactag tttcattcta   1740

atcaagatgt caaattgaat aaaaatcaca gcaatctctg attctgtgta ataatattga   1800

ataatttttt agaaggttac tgaaagctct gccttccgga atccctctaa gtctgcttga   1860

tagagtggat agtgtgttaa aactgtgtac tttaaaaaaa aattcaacct ttacatctag   1920

aataatttgc atctcatttt gcctaaattg gttctgtatt cataaacact ttccacatag   1980

aaaatagatt agtattacct gtggcacctt ttaagaaagg gtcaaatgtt tatatgctta   2040

agatacatag cctacttttt tttcgcagtt gttttctttt tttaaattga gttatgacaa   2100

ataaaaaatt gcatatattt aaggtgtac                                     2129


<210>  7029
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  7029

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Pro Ala Thr Val Thr Gln Val Thr Gln Gly Thr Ile Arg Pro Ala 
145                 150                 155                 160


Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu Ile Leu Arg Lys Ala Met 
                165                 170                 175


Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Val Asp Val Val Ala Asn 
            180                 185                 190


Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys Ala Ala Phe Lys Thr Ser 
        195                 200                 205


Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser Glu Leu Ser Gly Asn 
    210                 215                 220


Met Glu Glu Leu Ile Leu Ala Leu Phe Met Pro Pro Thr Tyr Tyr Asp 
225                 230                 235                 240


Ala Trp Ser Leu Arg Lys Ala Met Gln Gly Ala Gly Thr Gln Glu Arg 
                245                 250                 255


Val Leu Ile Glu Ile Leu Cys Thr Arg Thr Asn Gln Glu Ile Arg Glu 
            260                 265                 270


Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly Arg Asp Leu Glu Lys Asp 
        275                 280                 285


Ile Arg Ser Asp Thr Ser Gly His Phe Glu Arg Leu Leu Val Ser Met 
    290                 295                 300


Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser Ile Asn His Gln Met Ala 
305                 310                 315                 320


Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg Leu Gly 
                325                 330                 335


Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser Phe Pro 
            340                 345                 350


Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn Arg Asp 
        355                 360                 365


Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu Ser Gly 
    370                 375                 380


Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe Phe Ala 
385                 390                 395                 400


Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp Ser Thr 
                405                 410                 415


Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val Gln Ile 
            420                 425                 430


Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr Met Ile 
        435                 440                 445


Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala Ile Val 
    450                 455                 460


Gly Gln 
465


<210>  7030
<211>  2201
<212>  DNA
<213>  Homo sapiens

<400>  7030
caccctgggc ccgcccccgg ctccatcttg cgggagaccg ggttgggctg tgacgctgct     60

gctggggtca gaatgtcata cccaggctat cccccaacag gctacccacc tttccctgga    120

tatcctcctg caggtcagga gtcatctttt cccccttctg gtcagtatcc ttatcctagt    180

ggctttcctc caatgggagg aggtgcctac ccacaagtgc caagtagtgg ctacccagga    240

gctggaggct accctgcgcc tggaggttat ccagcccctg gaggctatcc tggtgcccca    300

cagccagggg gagctccatc ctatcccgga gttcctccag gccaaggatt tggagtccca    360

ccaggtggag caggcttttc tgggtatcca cagccacctt cacagtctta tggaggtggt    420

ccagcacagg ttccactacc tggtggcttt cctggaggac agatgccttc tcagtatcct    480

ggaggacaac ctacttaccc tagtcagatc aatacagatt ctttttcttc ctatcctgtt    540

ttctctcctg tttctttgga ttatagcagt gaacctgcca cagtgactca ggtcactcaa    600

ggaactatcc gaccagctgc caacttcgat gctataagag atgcagaaat tcttcgtaag    660

gcaatgaagg gttttgggac agatgagcag gcaattgtgg atgtggtggc caaccgttcc    720

aatgatcaga ggcaaaaaat taaagcagca tttaagacct cctatggcaa ggatttaatc    780

aaagatctca aatcagagtt aagtggaaat atggaagaac tgatcctggc cctcttcatg    840

cctcctacgt attacgatgc ctggagctta cggaaagcaa tgcagggagc aggaactcag    900

gaacgtgtat tgattgagat tttgtgcaca agaacaaatc aggaaatccg agaaattgtc    960

agatgttatc agtcagaatt tggacgagac cttgaaaagg acattaggtc agatacatca   1020

ggacattttg aacgtttact tgtgtccatg tgccagggaa atcgtgatga gaaccagagt   1080

ataaaccacc aaatggctca ggaagatgct cagcgtctct atcaagctgg tgaggggaga   1140

ctagggaccg atgaatcttg ctttaacatg atccttgcca caagaagctt tcctcagctg   1200

agagctacca tggaggctta ttctaggatg gctaatcgag acttgttaag cagtgtgagc   1260

cgtgagtttt ccggatatgt agaaagtggt ttgaagacca tcttgcagtg tgccctgaac   1320

cgccctgcct tctttgctga gaggctctac tatgctatga aaggtgctgg cacagatgac   1380

tccaccctgg tccggattgt ggtcactcga agtgagattg accttgtaca aataaaacag   1440

atgttcgctc agatgtatca gaagactctg ggcacaatga ttgcaggtga cacgagtgga   1500

gattaccgaa gacttcttct ggctattgtg ggccagtagg agggattttt ttttttttaa   1560

tgaaaaaaaa tttctattca tagcttatcc ttcagagcaa tgacctgcat gcagcaatat   1620

caaacatcag ctaaccgaaa gagctttctg tcaaggaccg tatcagggta atgtgcttgg   1680

tttgcacatg ttgttattgc cttaattcta attttatttt gttctctaca tacaatcaat   1740

gtaaagccat atcacaatga tacagtaata ttgcaatgtt tgtaaacctt cattcttact   1800

agtttcattc taatcaagat gtcaaattga ataaaaatca cagcaatctc tgattctgtg   1860

taataatatt gaataatttt ttagaaggtt actgaaagct ctgccttccg gaatccctct   1920

aagtctgctt gatagagtgg atagtgtgtt aaaactgtgt actttaaaaa aaaattcaac   1980

ctttacatct agaataattt gcatctcatt ttgcctaaat tggttctgta ttcataaaca   2040

ctttccacat agaaaataga ttagtattac ctgtggcacc ttttaagaaa gggtcaaatg   2100

tttatatgct taagatacat agcctacttt tttttcgcag ttgttttctt tttttaaatt   2160

gagttatgac aaataaaaaa ttgcatatat ttaaggtgta c                       2201


<210>  7031
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7031

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Ile Asn Thr Asp Ser Phe Ser Ser Tyr Pro Val Phe Ser Pro Val 
145                 150                 155                 160


Ser Leu Asp Tyr Ser Ser Glu Pro Ala Thr Val Thr Gln Val Thr Gln 
                165                 170                 175


Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu 
            180                 185                 190


Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile 
        195                 200                 205


Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys 
    210                 215                 220


Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys 
225                 230                 235                 240


Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu Phe Met 
                245                 250                 255


Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met Gln Gly 
            260                 265                 270


Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr Arg Thr 
        275                 280                 285


Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly 
    290                 295                 300


Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His Phe Glu 
305                 310                 315                 320


Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser 
                325                 330                 335


Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala 
            340                 345                 350


Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu 
        355                 360                 365


Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser 
    370                 375                 380


Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser 
385                 390                 395                 400


Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn 
                405                 410                 415


Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala 
            420                 425                 430


Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu 
        435                 440                 445


Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys 
    450                 455                 460


Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg 
465                 470                 475                 480


Leu Leu Leu Ala Ile Val Gly Gln 
                485


<210>  7032
<211>  1046
<212>  DNA
<213>  Homo sapiens

<400>  7032
ctttatgcag agttcaaggc ccagccctac cttttccagg gcatgagtag aggagtaact     60

tcctgagaaa gtgtgtgtga atccaaaggc aataatctgg gaaatttttt ggaaatcgtg    120

atgagaacca gagtataaac caccaaatgg ctcaggaaga tgctcagcgt ctctatcaag    180

ctggtgaggg gagactaggg accgatgaat cttgctttaa catgatcctt gccacaagaa    240

gctttcctca gctgagagct accatggagg cttattctag gatggctaat cgagacttgt    300

taagcagtgt gagccgtgag ttttccggat atgtagaaag tggtttgaag accatcttgc    360

agtgtgccct gaaccgccct gccttctttg ctgagaggct ctactatgct atgaaaggtg    420

ctggcacaga tgactccacc ctggtccgga ttgtggtcac tcgaagtgag attgaccttg    480

tacaaataaa acagatgttc gctcagatgt atcagaagac tctgggcaca atgattgcag    540

gtgacacgag tggagattac cgaagacttc ttctggctat tgtgggccag taggagggat    600

tttttttttt ttaatgaaaa aaaatttcta ttcatagctt atccttcaga gcaatgacct    660

gcatgcagca atatcaaaca tcagctaacc gaaagagctt tctgtcaagg accgtatcag    720

ggtaatgtgc ttggtttgca catgttgtta ttgccttaat tctaatttta ttttgttctc    780

tacatacaat caatgtaaag ccatatcaca atgatacagt aatattgcaa tgtttgtaaa    840

ccttcattct tactagtttc attctaatca agatgtcaaa ttgaataaaa atcacagcaa    900

tctctgattc tgtgtaataa tattgaataa ttttttagaa ggttactgaa agctctgcct    960

tccggaatcc ctctaagtct gcttgataga gtggatagtg tgttaaaact gtgtacttta   1020

aaaaaaaatt caacctttac atctag                                        1046


<210>  7033
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  7033

Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg 
1               5                   10                  15


Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser 
            20                  25                  30


Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn 
        35                  40                  45


Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu 
    50                  55                  60


Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe 
65                  70                  75                  80


Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp 
                85                  90                  95


Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val 
            100                 105                 110


Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr 
        115                 120                 125


Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala 
    130                 135                 140


Ile Val Gly Gln 
145


<210>  7034
<211>  1920
<212>  DNA
<213>  Homo sapiens

<400>  7034
gggcccgccc ccggctccat cttgcgggag accgggttgg gctgtgacgc tgctgctggg     60

gtcagaatgt catacccagg ctatccccca acaggctacc cacctttccc tggatatcct    120

cctgcaggtc aggagtcatc ttttccccct tctggtcagt atccttatcc tagtggcttt    180

cctccaatgg gaggaggtgc ctacccacaa gtgccaagta gtggctaccc aggagctgga    240

ggctaccctg cgcctggagg ttatccagcc cctggaggct atcctggtgc cccacagcca    300

gggggagctc catcctatcc cggagttcct ccaggccaag gatttggagt cccaccaggt    360

ggagcaggct tttctgggta tccacagcca ccttcacagt cttatggagg tggtccagca    420

caggttccac tacctggtgg ctttcctgga ggacagatgc cttctcagta tcctggagga    480

caacctactt accctagtca gcctgccaca gtgactcagg tcactcaagg aactatccga    540

ccagctgcca acttcgatgc tataagagat gcagaaattc ttcgtaaggc aatgaagggt    600

tttgggacag atgagcaggc aattgtggat gtggtggcca accgttccaa tgatcagagg    660

caaaaaatta aagcagcatt taagacctcc tatggcaagg atttaatcaa agatctcaaa    720

tcagagttaa gtggaaatat ggaagaactg atcctggccc tcttcatgcc tcctacgtat    780

tacgatgcct ggagcttacg gaaagcaatg cagggagcag gaactcagga acgtgtattg    840

attgagattt tgtgcacaag aacaaatcag gaaatccgag aaattgtcag atgttatcag    900

tcagaatttg gacgagacct tgaaaaggac attaggtcag atacatcagg acattttgaa    960

cgtttacttg tgtccatgtg ccagggaaat cgtgatgaga accagagtat aaaccaccaa   1020

atggctcagg aagatgctca gcgtctctat caagctggtg aggggagact agggaccgat   1080

gaatcttgct ttaacatgat ccttgccaca agaagctttc ctcagctgag agctaccatg   1140

gaggcttatt ctaggatggc taatcgagac ttgttaagca gtgtgagccg tgagttttcc   1200

ggatatgtag aaagtggttt gaagaccatc ttgcagtgtg ccctgaaccg ccctgccttc   1260

tttgctgaga ggctctacta tgctatgaaa ggtgctggca cagatgactc caccctggtc   1320

cggattgtgg tcactcgaag tgagattgac cttgtacaaa taaaacagat gttcgctcag   1380

atgtatcaga agactctggg cacaatgatt gcaggtgaca cgagtggaga ttaccgaaga   1440

cttcttctgg ctattgtggg ccagtaggag ggattttttt ttttttaatg aaaaaaaatt   1500

tctattcata gcttatcctt cagagcaatg acctgcatgc agcaatatca aacatcagct   1560

aaccgaaaga gctttctgtc aaggaccgta tcagggtaat gtgcttggtt tgcacatgtt   1620

gttattgcct taattctaat tttattttgt tctctacata caatcaatgt aaagccatat   1680

cacaatgata cagtaatatt gcaatgtttg taaaccttca ttcttactag tttcattcta   1740

atcaagatgt caaattgaat aaaaatcaca gcaatctctg attctgtgta ataatattga   1800

ataatttttt agaaggttac tgaaagctct gccttccgga atccctctaa gtctgcttga   1860

tagagtggat agtgtgttaa aactgtgtac tttaaaaaaa aattcaacct ttacatctag   1920


<210>  7035
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  7035

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Pro Ala Thr Val Thr Gln Val Thr Gln Gly Thr Ile Arg Pro Ala 
145                 150                 155                 160


Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu Ile Leu Arg Lys Ala Met 
                165                 170                 175


Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Val Asp Val Val Ala Asn 
            180                 185                 190


Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys Ala Ala Phe Lys Thr Ser 
        195                 200                 205


Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser Glu Leu Ser Gly Asn 
    210                 215                 220


Met Glu Glu Leu Ile Leu Ala Leu Phe Met Pro Pro Thr Tyr Tyr Asp 
225                 230                 235                 240


Ala Trp Ser Leu Arg Lys Ala Met Gln Gly Ala Gly Thr Gln Glu Arg 
                245                 250                 255


Val Leu Ile Glu Ile Leu Cys Thr Arg Thr Asn Gln Glu Ile Arg Glu 
            260                 265                 270


Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly Arg Asp Leu Glu Lys Asp 
        275                 280                 285


Ile Arg Ser Asp Thr Ser Gly His Phe Glu Arg Leu Leu Val Ser Met 
    290                 295                 300


Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser Ile Asn His Gln Met Ala 
305                 310                 315                 320


Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg Leu Gly 
                325                 330                 335


Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser Phe Pro 
            340                 345                 350


Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn Arg Asp 
        355                 360                 365


Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu Ser Gly 
    370                 375                 380


Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe Phe Ala 
385                 390                 395                 400


Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp Ser Thr 
                405                 410                 415


Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val Gln Ile 
            420                 425                 430


Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr Met Ile 
        435                 440                 445


Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala Ile Val 
    450                 455                 460


Gly Gln 
465


<210>  7036
<211>  1992
<212>  DNA
<213>  Homo sapiens

<400>  7036
caccctgggc ccgcccccgg ctccatcttg cgggagaccg ggttgggctg tgacgctgct     60

gctggggtca gaatgtcata cccaggctat cccccaacag gctacccacc tttccctgga    120

tatcctcctg caggtcagga gtcatctttt cccccttctg gtcagtatcc ttatcctagt    180

ggctttcctc caatgggagg aggtgcctac ccacaagtgc caagtagtgg ctacccagga    240

gctggaggct accctgcgcc tggaggttat ccagcccctg gaggctatcc tggtgcccca    300

cagccagggg gagctccatc ctatcccgga gttcctccag gccaaggatt tggagtccca    360

ccaggtggag caggcttttc tgggtatcca cagccacctt cacagtctta tggaggtggt    420

ccagcacagg ttccactacc tggtggcttt cctggaggac agatgccttc tcagtatcct    480

ggaggacaac ctacttaccc tagtcagatc aatacagatt ctttttcttc ctatcctgtt    540

ttctctcctg tttctttgga ttatagcagt gaacctgcca cagtgactca ggtcactcaa    600

ggaactatcc gaccagctgc caacttcgat gctataagag atgcagaaat tcttcgtaag    660

gcaatgaagg gttttgggac agatgagcag gcaattgtgg atgtggtggc caaccgttcc    720

aatgatcaga ggcaaaaaat taaagcagca tttaagacct cctatggcaa ggatttaatc    780

aaagatctca aatcagagtt aagtggaaat atggaagaac tgatcctggc cctcttcatg    840

cctcctacgt attacgatgc ctggagctta cggaaagcaa tgcagggagc aggaactcag    900

gaacgtgtat tgattgagat tttgtgcaca agaacaaatc aggaaatccg agaaattgtc    960

agatgttatc agtcagaatt tggacgagac cttgaaaagg acattaggtc agatacatca   1020

ggacattttg aacgtttact tgtgtccatg tgccagggaa atcgtgatga gaaccagagt   1080

ataaaccacc aaatggctca ggaagatgct cagcgtctct atcaagctgg tgaggggaga   1140

ctagggaccg atgaatcttg ctttaacatg atccttgcca caagaagctt tcctcagctg   1200

agagctacca tggaggctta ttctaggatg gctaatcgag acttgttaag cagtgtgagc   1260

cgtgagtttt ccggatatgt agaaagtggt ttgaagacca tcttgcagtg tgccctgaac   1320

cgccctgcct tctttgctga gaggctctac tatgctatga aaggtgctgg cacagatgac   1380

tccaccctgg tccggattgt ggtcactcga agtgagattg accttgtaca aataaaacag   1440

atgttcgctc agatgtatca gaagactctg ggcacaatga ttgcaggtga cacgagtgga   1500

gattaccgaa gacttcttct ggctattgtg ggccagtagg agggattttt ttttttttaa   1560

tgaaaaaaaa tttctattca tagcttatcc ttcagagcaa tgacctgcat gcagcaatat   1620

caaacatcag ctaaccgaaa gagctttctg tcaaggaccg tatcagggta atgtgcttgg   1680

tttgcacatg ttgttattgc cttaattcta attttatttt gttctctaca tacaatcaat   1740

gtaaagccat atcacaatga tacagtaata ttgcaatgtt tgtaaacctt cattcttact   1800

agtttcattc taatcaagat gtcaaattga ataaaaatca cagcaatctc tgattctgtg   1860

taataatatt gaataatttt ttagaaggtt actgaaagct ctgccttccg gaatccctct   1920

aagtctgctt gatagagtgg atagtgtgtt aaaactgtgt actttaaaaa aaaattcaac   1980

ctttacatct ag                                                       1992


<210>  7037
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7037

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Ile Asn Thr Asp Ser Phe Ser Ser Tyr Pro Val Phe Ser Pro Val 
145                 150                 155                 160


Ser Leu Asp Tyr Ser Ser Glu Pro Ala Thr Val Thr Gln Val Thr Gln 
                165                 170                 175


Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu 
            180                 185                 190


Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile 
        195                 200                 205


Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys 
    210                 215                 220


Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys 
225                 230                 235                 240


Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu Phe Met 
                245                 250                 255


Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met Gln Gly 
            260                 265                 270


Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr Arg Thr 
        275                 280                 285


Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly 
    290                 295                 300


Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His Phe Glu 
305                 310                 315                 320


Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser 
                325                 330                 335


Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala 
            340                 345                 350


Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu 
        355                 360                 365


Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser 
    370                 375                 380


Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser 
385                 390                 395                 400


Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn 
                405                 410                 415


Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala 
            420                 425                 430


Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu 
        435                 440                 445


Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys 
    450                 455                 460


Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg 
465                 470                 475                 480


Leu Leu Leu Ala Ile Val Gly Gln 
                485


<210>  7038
<211>  915
<212>  DNA
<213>  Homo sapiens

<400>  7038
ctttatgcag agttcaaggc ccagccctac cttttccagg gcatgagtag aggagtaact     60

tcctgagaaa gtgtgtgtga atccaaaggc aataatctgg gaaatttttt ggaaatcgtg    120

atgagaacca gagtataaac caccaaatgg ctcaggaaga tgctcagcgt ctctatcaag    180

ctggtgaggg gagactaggg accgatgaat cttgctttaa catgatcctt gccacaagaa    240

gctttcctca gctgagagct accatggagg cttattctag gatggctaat cgagacttgt    300

taagcagtgt gagccgtgag ttttccggat atgtagaaag tggtttgaag accatcttgc    360

agtgtgccct gaaccgccct gccttctttg ctgagaggct ctactatgct atgaaaggtg    420

ctggcacaga tgactccacc ctggtccgga ttgtggtcac tcgaagtgag attgaccttg    480

tacaaataaa acagatgttc gctcagatgt atcagaagac tctgggcaca atgattgcag    540

gtgacacgag tggagattac cgaagacttc ttctggctat tgtgggccag taggagggat    600

tttttttttt ttaatgaaaa aaaatttcta ttcatagctt atccttcaga gcaatgacct    660

gcatgcagca atatcaaaca tcagctaacc gaaagagctt tctgtcaagg accgtatcag    720

ggtaatgtgc ttggtttgca catgttgtta ttgccttaat tctaatttta ttttgttctc    780

tacatacaat caatgtaaag ccatatcaca atgatacagt aatattgcaa tgtttgtaaa    840

ccttcattct tactagtttc attctaatca agatgtcaaa ttgaataaaa atcacagcaa    900

tctctgattc tgtgt                                                     915


<210>  7039
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  7039

Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg 
1               5                   10                  15


Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser 
            20                  25                  30


Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn 
        35                  40                  45


Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu 
    50                  55                  60


Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe 
65                  70                  75                  80


Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp 
                85                  90                  95


Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val 
            100                 105                 110


Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr 
        115                 120                 125


Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala 
    130                 135                 140


Ile Val Gly Gln 
145


<210>  7040
<211>  1789
<212>  DNA
<213>  Homo sapiens

<400>  7040
gggcccgccc ccggctccat cttgcgggag accgggttgg gctgtgacgc tgctgctggg     60

gtcagaatgt catacccagg ctatccccca acaggctacc cacctttccc tggatatcct    120

cctgcaggtc aggagtcatc ttttccccct tctggtcagt atccttatcc tagtggcttt    180

cctccaatgg gaggaggtgc ctacccacaa gtgccaagta gtggctaccc aggagctgga    240

ggctaccctg cgcctggagg ttatccagcc cctggaggct atcctggtgc cccacagcca    300

gggggagctc catcctatcc cggagttcct ccaggccaag gatttggagt cccaccaggt    360

ggagcaggct tttctgggta tccacagcca ccttcacagt cttatggagg tggtccagca    420

caggttccac tacctggtgg ctttcctgga ggacagatgc cttctcagta tcctggagga    480

caacctactt accctagtca gcctgccaca gtgactcagg tcactcaagg aactatccga    540

ccagctgcca acttcgatgc tataagagat gcagaaattc ttcgtaaggc aatgaagggt    600

tttgggacag atgagcaggc aattgtggat gtggtggcca accgttccaa tgatcagagg    660

caaaaaatta aagcagcatt taagacctcc tatggcaagg atttaatcaa agatctcaaa    720

tcagagttaa gtggaaatat ggaagaactg atcctggccc tcttcatgcc tcctacgtat    780

tacgatgcct ggagcttacg gaaagcaatg cagggagcag gaactcagga acgtgtattg    840

attgagattt tgtgcacaag aacaaatcag gaaatccgag aaattgtcag atgttatcag    900

tcagaatttg gacgagacct tgaaaaggac attaggtcag atacatcagg acattttgaa    960

cgtttacttg tgtccatgtg ccagggaaat cgtgatgaga accagagtat aaaccaccaa   1020

atggctcagg aagatgctca gcgtctctat caagctggtg aggggagact agggaccgat   1080

gaatcttgct ttaacatgat ccttgccaca agaagctttc ctcagctgag agctaccatg   1140

gaggcttatt ctaggatggc taatcgagac ttgttaagca gtgtgagccg tgagttttcc   1200

ggatatgtag aaagtggttt gaagaccatc ttgcagtgtg ccctgaaccg ccctgccttc   1260

tttgctgaga ggctctacta tgctatgaaa ggtgctggca cagatgactc caccctggtc   1320

cggattgtgg tcactcgaag tgagattgac cttgtacaaa taaaacagat gttcgctcag   1380

atgtatcaga agactctggg cacaatgatt gcaggtgaca cgagtggaga ttaccgaaga   1440

cttcttctgg ctattgtggg ccagtaggag ggattttttt ttttttaatg aaaaaaaatt   1500

tctattcata gcttatcctt cagagcaatg acctgcatgc agcaatatca aacatcagct   1560

aaccgaaaga gctttctgtc aaggaccgta tcagggtaat gtgcttggtt tgcacatgtt   1620

gttattgcct taattctaat tttattttgt tctctacata caatcaatgt aaagccatat   1680

cacaatgata cagtaatatt gcaatgtttg taaaccttca ttcttactag tttcattcta   1740

atcaagatgt caaattgaat aaaaatcaca gcaatctctg attctgtgt               1789


<210>  7041
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  7041

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Pro Ala Thr Val Thr Gln Val Thr Gln Gly Thr Ile Arg Pro Ala 
145                 150                 155                 160


Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu Ile Leu Arg Lys Ala Met 
                165                 170                 175


Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile Val Asp Val Val Ala Asn 
            180                 185                 190


Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys Ala Ala Phe Lys Thr Ser 
        195                 200                 205


Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys Ser Glu Leu Ser Gly Asn 
    210                 215                 220


Met Glu Glu Leu Ile Leu Ala Leu Phe Met Pro Pro Thr Tyr Tyr Asp 
225                 230                 235                 240


Ala Trp Ser Leu Arg Lys Ala Met Gln Gly Ala Gly Thr Gln Glu Arg 
                245                 250                 255


Val Leu Ile Glu Ile Leu Cys Thr Arg Thr Asn Gln Glu Ile Arg Glu 
            260                 265                 270


Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly Arg Asp Leu Glu Lys Asp 
        275                 280                 285


Ile Arg Ser Asp Thr Ser Gly His Phe Glu Arg Leu Leu Val Ser Met 
    290                 295                 300


Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser Ile Asn His Gln Met Ala 
305                 310                 315                 320


Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala Gly Glu Gly Arg Leu Gly 
                325                 330                 335


Thr Asp Glu Ser Cys Phe Asn Met Ile Leu Ala Thr Arg Ser Phe Pro 
            340                 345                 350


Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser Arg Met Ala Asn Arg Asp 
        355                 360                 365


Leu Leu Ser Ser Val Ser Arg Glu Phe Ser Gly Tyr Val Glu Ser Gly 
    370                 375                 380


Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn Arg Pro Ala Phe Phe Ala 
385                 390                 395                 400


Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala Gly Thr Asp Asp Ser Thr 
                405                 410                 415


Leu Val Arg Ile Val Val Thr Arg Ser Glu Ile Asp Leu Val Gln Ile 
            420                 425                 430


Lys Gln Met Phe Ala Gln Met Tyr Gln Lys Thr Leu Gly Thr Met Ile 
        435                 440                 445


Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg Leu Leu Leu Ala Ile Val 
    450                 455                 460


Gly Gln 
465


<210>  7042
<211>  1861
<212>  DNA
<213>  Homo sapiens

<400>  7042
caccctgggc ccgcccccgg ctccatcttg cgggagaccg ggttgggctg tgacgctgct     60

gctggggtca gaatgtcata cccaggctat cccccaacag gctacccacc tttccctgga    120

tatcctcctg caggtcagga gtcatctttt cccccttctg gtcagtatcc ttatcctagt    180

ggctttcctc caatgggagg aggtgcctac ccacaagtgc caagtagtgg ctacccagga    240

gctggaggct accctgcgcc tggaggttat ccagcccctg gaggctatcc tggtgcccca    300

cagccagggg gagctccatc ctatcccgga gttcctccag gccaaggatt tggagtccca    360

ccaggtggag caggcttttc tgggtatcca cagccacctt cacagtctta tggaggtggt    420

ccagcacagg ttccactacc tggtggcttt cctggaggac agatgccttc tcagtatcct    480

ggaggacaac ctacttaccc tagtcagatc aatacagatt ctttttcttc ctatcctgtt    540

ttctctcctg tttctttgga ttatagcagt gaacctgcca cagtgactca ggtcactcaa    600

ggaactatcc gaccagctgc caacttcgat gctataagag atgcagaaat tcttcgtaag    660

gcaatgaagg gttttgggac agatgagcag gcaattgtgg atgtggtggc caaccgttcc    720

aatgatcaga ggcaaaaaat taaagcagca tttaagacct cctatggcaa ggatttaatc    780

aaagatctca aatcagagtt aagtggaaat atggaagaac tgatcctggc cctcttcatg    840

cctcctacgt attacgatgc ctggagctta cggaaagcaa tgcagggagc aggaactcag    900

gaacgtgtat tgattgagat tttgtgcaca agaacaaatc aggaaatccg agaaattgtc    960

agatgttatc agtcagaatt tggacgagac cttgaaaagg acattaggtc agatacatca   1020

ggacattttg aacgtttact tgtgtccatg tgccagggaa atcgtgatga gaaccagagt   1080

ataaaccacc aaatggctca ggaagatgct cagcgtctct atcaagctgg tgaggggaga   1140

ctagggaccg atgaatcttg ctttaacatg atccttgcca caagaagctt tcctcagctg   1200

agagctacca tggaggctta ttctaggatg gctaatcgag acttgttaag cagtgtgagc   1260

cgtgagtttt ccggatatgt agaaagtggt ttgaagacca tcttgcagtg tgccctgaac   1320

cgccctgcct tctttgctga gaggctctac tatgctatga aaggtgctgg cacagatgac   1380

tccaccctgg tccggattgt ggtcactcga agtgagattg accttgtaca aataaaacag   1440

atgttcgctc agatgtatca gaagactctg ggcacaatga ttgcaggtga cacgagtgga   1500

gattaccgaa gacttcttct ggctattgtg ggccagtagg agggattttt ttttttttaa   1560

tgaaaaaaaa tttctattca tagcttatcc ttcagagcaa tgacctgcat gcagcaatat   1620

caaacatcag ctaaccgaaa gagctttctg tcaaggaccg tatcagggta atgtgcttgg   1680

tttgcacatg ttgttattgc cttaattcta attttatttt gttctctaca tacaatcaat   1740

gtaaagccat atcacaatga tacagtaata ttgcaatgtt tgtaaacctt cattcttact   1800

agtttcattc taatcaagat gtcaaattga ataaaaatca cagcaatctc tgattctgtg   1860

t                                                                   1861


<210>  7043
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7043

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala Pro Gly 
    50                  55                  60


Gly Tyr Pro Ala Pro Gly Gly Tyr Pro Gly Ala Pro Gln Pro Gly Gly 
65                  70                  75                  80


Ala Pro Ser Tyr Pro Gly Val Pro Pro Gly Gln Gly Phe Gly Val Pro 
                85                  90                  95


Pro Gly Gly Ala Gly Phe Ser Gly Tyr Pro Gln Pro Pro Ser Gln Ser 
            100                 105                 110


Tyr Gly Gly Gly Pro Ala Gln Val Pro Leu Pro Gly Gly Phe Pro Gly 
        115                 120                 125


Gly Gln Met Pro Ser Gln Tyr Pro Gly Gly Gln Pro Thr Tyr Pro Ser 
    130                 135                 140


Gln Ile Asn Thr Asp Ser Phe Ser Ser Tyr Pro Val Phe Ser Pro Val 
145                 150                 155                 160


Ser Leu Asp Tyr Ser Ser Glu Pro Ala Thr Val Thr Gln Val Thr Gln 
                165                 170                 175


Gly Thr Ile Arg Pro Ala Ala Asn Phe Asp Ala Ile Arg Asp Ala Glu 
            180                 185                 190


Ile Leu Arg Lys Ala Met Lys Gly Phe Gly Thr Asp Glu Gln Ala Ile 
        195                 200                 205


Val Asp Val Val Ala Asn Arg Ser Asn Asp Gln Arg Gln Lys Ile Lys 
    210                 215                 220


Ala Ala Phe Lys Thr Ser Tyr Gly Lys Asp Leu Ile Lys Asp Leu Lys 
225                 230                 235                 240


Ser Glu Leu Ser Gly Asn Met Glu Glu Leu Ile Leu Ala Leu Phe Met 
                245                 250                 255


Pro Pro Thr Tyr Tyr Asp Ala Trp Ser Leu Arg Lys Ala Met Gln Gly 
            260                 265                 270


Ala Gly Thr Gln Glu Arg Val Leu Ile Glu Ile Leu Cys Thr Arg Thr 
        275                 280                 285


Asn Gln Glu Ile Arg Glu Ile Val Arg Cys Tyr Gln Ser Glu Phe Gly 
    290                 295                 300


Arg Asp Leu Glu Lys Asp Ile Arg Ser Asp Thr Ser Gly His Phe Glu 
305                 310                 315                 320


Arg Leu Leu Val Ser Met Cys Gln Gly Asn Arg Asp Glu Asn Gln Ser 
                325                 330                 335


Ile Asn His Gln Met Ala Gln Glu Asp Ala Gln Arg Leu Tyr Gln Ala 
            340                 345                 350


Gly Glu Gly Arg Leu Gly Thr Asp Glu Ser Cys Phe Asn Met Ile Leu 
        355                 360                 365


Ala Thr Arg Ser Phe Pro Gln Leu Arg Ala Thr Met Glu Ala Tyr Ser 
    370                 375                 380


Arg Met Ala Asn Arg Asp Leu Leu Ser Ser Val Ser Arg Glu Phe Ser 
385                 390                 395                 400


Gly Tyr Val Glu Ser Gly Leu Lys Thr Ile Leu Gln Cys Ala Leu Asn 
                405                 410                 415


Arg Pro Ala Phe Phe Ala Glu Arg Leu Tyr Tyr Ala Met Lys Gly Ala 
            420                 425                 430


Gly Thr Asp Asp Ser Thr Leu Val Arg Ile Val Val Thr Arg Ser Glu 
        435                 440                 445


Ile Asp Leu Val Gln Ile Lys Gln Met Phe Ala Gln Met Tyr Gln Lys 
    450                 455                 460


Thr Leu Gly Thr Met Ile Ala Gly Asp Thr Ser Gly Asp Tyr Arg Arg 
465                 470                 475                 480


Leu Leu Leu Ala Ile Val Gly Gln 
                485


<210>  7044
<211>  401
<212>  DNA
<213>  Homo sapiens

<400>  7044
tacagtggta attaaagcaa ttctttattt cacatcatcc atctgaatat atagttttta     60

gttctacaga acaaagaaat atttgacgaa gatttaatta cttgcagaaa tttcattttt    120

ctttgtataa tcttcccttc atttcatgta gggagcagga actcaggaac gtgtattgat    180

tgagattttg tgcacaagaa caaatcagga aatccgagaa attgtcagat gttatcagtc    240

agaatttgga cgagaccttt tcctgtgtta tattcagtcg cccatgtaga atgtgcctct    300

acgtattcct tgtgccagtt gctcagaaga cagttcttca gcttcaagga ggatttttcc    360

atcttattcc aaagatggtc cctgagactc taaaaggcag c                        401


<210>  7045
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  7045

Met Leu Ser Val Arg Ile Trp Thr Arg Pro Phe Pro Val Leu Tyr Ser 
1               5                   10                  15


Val Ala His Val Glu Cys Ala Ser Thr Tyr Ser Leu Cys Gln Leu Leu 
            20                  25                  30


Arg Arg Gln Phe Phe Ser Phe Lys Glu Asp Phe Ser Ile Leu Phe Gln 
        35                  40                  45


Arg Trp Ser Leu Arg Leu 
    50


<210>  7046
<211>  424
<212>  DNA
<213>  Homo sapiens

<400>  7046
tcagattttt ttttccttta ttttgaccct gacccttttg cccttggtct atctactttt     60

ctttttcttt cttttttttt ttctttttcc ttgtcttgtc ttgtcttttc tttcaactgg    120

agtgcaatga tgcaaacacg actcactgcc gccttgacct cctggcctca agcaattctc    180

ccacctcagc ttcctgaata gtttggacta caggtgggcg ccgctgcact ggaatgtcat    240

acccaggcta tcccccaaca ggctacccac ctttccctgg atatcctcct gcaggtcagg    300

agtcatcttt tcccccttct ggtcagtatc cttatcctag tggctttcct ccaatgggag    360

gaggtgccta cccacaagtg ccaagtagtg gctacccagg agctggaggc taccctgcgc    420

ctgg                                                                 424


<210>  7047
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  7047

Met Ser Tyr Pro Gly Tyr Pro Pro Thr Gly Tyr Pro Pro Phe Pro Gly 
1               5                   10                  15


Tyr Pro Pro Ala Gly Gln Glu Ser Ser Phe Pro Pro Ser Gly Gln Tyr 
            20                  25                  30


Pro Tyr Pro Ser Gly Phe Pro Pro Met Gly Gly Gly Ala Tyr Pro Gln 
        35                  40                  45


Val Pro Ser Ser Gly Tyr Pro Gly Ala Gly Gly Tyr Pro Ala 
    50                  55                  60


<210>  7048
<211>  1992
<212>  DNA
<213>  Homo sapiens

<400>  7048
atttcacttg gaggaaagag agaaggaagg aagctgagga cttagcaggg tatcactgga     60

caggccatgg ctccacggtc ccggcgacga aggcacaaga aacctccctc atcagtggct    120

cccatcatca tggccccaac cacaattgtg acccctgtgc ctctgacccc ctcaaaacct    180

ggccctagca ttgacacact tggcttcttc tccttggatg ataatgttcc tggcctatcg    240

cagctgatcc ttcaaaagct gaacatgaaa agctatgaag aatataagtt ggtggtagat    300

gggggtaccc ccgtatcagg ctttggattt cgatgtcctc aagaaatgtt ccagaggatg    360

gaagacacat ttcgattctg tgctcactgt agagcactcc ctagtgggct ttcagactcc    420

aaggttctcc ggcactgtaa gaggtgcaga aatgtctatt actgtggtcc agagtgccag    480

aagtcagact ggcccgcaca caggagggtt tgtcaagagc ttcgtcttgt ggctgtggac    540

cgtctcatgg aatggcttct ggtcacagag cacctcaact tcacccctgg aacctggcac    600

aattcagctt agtgcccaca ggggcctcta ccatgacttc tgggaggagc aagtagagac    660

cgggcagaca caccatccag atttggtggc ggcattccat ccaggttttc attcctcccc    720

agacttgatg gaggcttggc tgcccaccct gctgctactt cgtgactata agattcctac    780

attgattact gtttacagcc atcaggagtt ggtatcctct ttgcagattc tggtggaact    840

ggatacacac atcactgcct ttgggtctaa tcctttcatg tccctcaaac ctgaacaggt    900

ctattccagt cccaacaagc agccagtata ctgcagtgca tactatatca tgtttcttgg    960

aagctcctgt cagctggata ataggcaatt agaagagaaa gtggacggcg ggatttaaat   1020

agatcataac tggacatctg gaaaacgggg agtttgtgat gaaattaccc tgctaatgcc   1080

aggttcttgc aaactttgaa aaacattata ttctaaacct catttactgt ttgggtaaaa   1140

attctaagct gaatgagagt ttctgtataa cataactggt ttctttcttt ttttgagatg   1200

gagtcttgct ctgttgccca ggctggagtg cagcggcatg atctcgactc actgcagcct   1260

ccgcctcctg ggttcaagtg gttctcctgc ctcagcctcc ctagtagctg ggattacagg   1320

tgcacaccac cacacctggc taatttttgt atttttagca gacagggttt caccatgttg   1380

gccaggctcg tatcaaaccc ttgaccccag gtgatctgcc tgcctcagcc tcccaaagtt   1440

ctgggattac aggcatgagc caccatgccc agccaatgta actggtttct aagagtttag   1500

ccacagtagc ttctagagat aggaaattag atttagtggg tgggaagagg ccctgatgct   1560

ggtctttcca gagcttatag ttgctaacac ttttctttgt aaagaagttt accttttgac   1620

tggaaccaga tggcactgag aaaaagaatg agaaccacct tattcttctg aaaaagactt   1680

tcttctcatc cagtaatttg ggctaaaaaa tggaaagatg ttgatgactt gaagtgatgc   1740

aagaatggac aagtcaggga agtcattggg aacatggatg aggttgtaag cattggtaca   1800

gtgtcctgtt tcctgacttt tttgagagaa atgtctactt ttcctgtttt ctcttgggga   1860

cttttgaccc tagagtagcc ctggtgttat attttagata tcccaagcta tatcagactt   1920

tacctgaata tactggagtt acttattatc ccccattcta taccccaata aactcagttt   1980

ggggcttctt aa                                                       1992


<210>  7049
<211>  239
<212>  PRT
<213>  Homo sapiens

<400>  7049

Met Gly Val Pro Pro Tyr Gln Ala Leu Asp Phe Asp Val Leu Lys Lys 
1               5                   10                  15


Cys Ser Arg Gly Trp Lys Thr His Phe Asp Ser Val Leu Thr Val Glu 
            20                  25                  30


His Ser Leu Val Gly Phe Gln Thr Pro Arg Phe Ser Gly Thr Val Arg 
        35                  40                  45


Gly Ala Glu Met Ser Ile Thr Val Val Gln Ser Ala Arg Ser Gln Thr 
    50                  55                  60


Gly Pro His Thr Gly Gly Phe Val Lys Ser Phe Val Leu Trp Leu Trp 
65                  70                  75                  80


Thr Val Ser Trp Asn Gly Phe Trp Ser Gln Ser Thr Ser Thr Ser Pro 
                85                  90                  95


Leu Glu Pro Gly Thr Ile Gln Leu Ser Ala His Arg Gly Leu Tyr His 
            100                 105                 110


Asp Phe Trp Glu Glu Gln Val Glu Thr Gly Gln Thr His His Pro Asp 
        115                 120                 125


Leu Val Ala Ala Phe His Pro Gly Phe His Ser Ser Pro Asp Leu Met 
    130                 135                 140


Glu Ala Trp Leu Pro Thr Leu Leu Leu Leu Arg Asp Tyr Lys Ile Pro 
145                 150                 155                 160


Thr Leu Ile Thr Val Tyr Ser His Gln Glu Leu Val Ser Ser Leu Gln 
                165                 170                 175


Ile Leu Val Glu Leu Asp Thr His Ile Thr Ala Phe Gly Ser Asn Pro 
            180                 185                 190


Phe Met Ser Leu Lys Pro Glu Gln Val Tyr Ser Ser Pro Asn Lys Gln 
        195                 200                 205


Pro Val Tyr Cys Ser Ala Tyr Tyr Ile Met Phe Leu Gly Ser Ser Cys 
    210                 215                 220


Gln Leu Asp Asn Arg Gln Leu Glu Glu Lys Val Asp Gly Gly Ile 
225                 230                 235


<210>  7050
<211>  2423
<212>  DNA
<213>  Homo sapiens

<400>  7050
atttcacttg gaggaaagag agaaggaagg aagctgagga cttagcaggg tatcactgga     60

caggccatgg ctccacggtc ccggcgacga aggcacaaga aacctccctc atcagtggct    120

cccatcatca tggccccaac cacaattgtg acccctgtgc ctctgacccc ctcaaaacct    180

ggccctagca ttgacacact tggcttcttc tccttggatg ataatgttcc tggcctatcg    240

cagctgatcc ttcaaaagct gaacatgaaa agctatgaag aatataagtt ggtggtagat    300

gggggtaccc ccgtatcagg ctttggattt cgatgtcctc aagaaatgtt ccagaggatg    360

gaagacacat ttcgattctg tgctcactgt agagcactcc ctagtgggct ttcagactcc    420

aaggttctcc ggcactgtaa gaggtgcaga aatgtctatt actgtggtcc agagtgccag    480

aagtcagact ggcccgcaca caggagggtt tgtcaagagc ttcgtcttgt ggctgtggac    540

cgtctcatgg aatggcttct ggtcacaggt gattttgttc taccctcagg accttggcca    600

tggccacctg aagctgtaca ggactgggac tcctggtttt ctatgaaggg gttacaccta    660

gatgctacat tggatgctgt gctagttagt catgctgtga ccaccttatg ggccagtgta    720

ggacggccaa ggccagaccc ggatgtcctg cagggatctt tgaagcggct gctgacagat    780

gtcctgtcac ggcccttgac tctaggccta ggacttaggg ccttggggat agatgttagg    840

aggactgggg gaagcacagt gcatgtggtt ggtgcttccc atgtggagac atttcttact    900

cgcccagggg actatgatga gcttggttac atgtttcctg ggcaccttgg actccgtgtg    960

gtcatggtgg gtgtagatgt agctactggc ttttcacaga gcacctcaac ttcacccctg   1020

gaacctggca caattcagct tagtgcccac aggggcctct accatgactt ctgggaggag   1080

caagtagaga ccgggcagac acaccatcca gatttggtgg cggcattcca tccaggtttt   1140

cattcctccc cagacttgat ggaggcttgg ctgcccaccc tgctgctact tcgtgactat   1200

aagattccta cattgattac tgtttacagc catcaggagt tggtatcctc tttgcagatt   1260

ctggtggaac tggatacaca catcactgcc tttgggtcta atcctttcat gtccctcaaa   1320

cctgaacagg tctattccag tcccaacaag cagccagtat actgcagtgc atactatatc   1380

atgtttcttg gaagctcctg tcagctggat aataggcaat tagaagagaa agtggacggc   1440

gggatttaaa tagatcataa ctggacatct ggaaaacggg gagtttgtga tgaaattacc   1500

ctgctaatgc caggttcttg caaactttga aaaacattat attctaaacc tcatttactg   1560

tttgggtaaa aattctaagc tgaatgagag tttctgtata acataactgg tttctttctt   1620

tttttgagat ggagtcttgc tctgttgccc aggctggagt gcagcggcat gatctcgact   1680

cactgcagcc tccgcctcct gggttcaagt ggttctcctg cctcagcctc cctagtagct   1740

gggattacag gtgcacacca ccacacctgg ctaatttttg tatttttagc agacagggtt   1800

tcaccatgtt ggccaggctc gtatcaaacc cttgacccca ggtgatctgc ctgcctcagc   1860

ctcccaaagt tctgggatta caggcatgag ccaccatgcc cagccaatgt aactggtttc   1920

taagagttta gccacagtag cttctagaga taggaaatta gatttagtgg gtgggaagag   1980

gccctgatgc tggtctttcc agagcttata gttgctaaca cttttctttg taaagaagtt   2040

taccttttga ctggaaccag atggcactga gaaaaagaat gagaaccacc ttattcttct   2100

gaaaaagact ttcttctcat ccagtaattt gggctaaaaa atggaaagat gttgatgact   2160

tgaagtgatg caagaatgga caagtcaggg aagtcattgg gaacatggat gaggttgtaa   2220

gcattggtac agtgtcctgt ttcctgactt ttttgagaga aatgtctact tttcctgttt   2280

tctcttgggg acttttgacc ctagagtagc cctggtgtta tattttagat atcccaagct   2340

atatcagact ttacctgaat atactggagt tacttattat cccccattct ataccccaat   2400

aaactcagtt tggggcttct taa                                           2423


<210>  7051
<211>  460
<212>  PRT
<213>  Homo sapiens

<400>  7051

Met Ala Pro Arg Ser Arg Arg Arg Arg His Lys Lys Pro Pro Ser Ser 
1               5                   10                  15


Val Ala Pro Ile Ile Met Ala Pro Thr Thr Ile Val Thr Pro Val Pro 
            20                  25                  30


Leu Thr Pro Ser Lys Pro Gly Pro Ser Ile Asp Thr Leu Gly Phe Phe 
        35                  40                  45


Ser Leu Asp Asp Asn Val Pro Gly Leu Ser Gln Leu Ile Leu Gln Lys 
    50                  55                  60


Leu Asn Met Lys Ser Tyr Glu Glu Tyr Lys Leu Val Val Asp Gly Gly 
65                  70                  75                  80


Thr Pro Val Ser Gly Phe Gly Phe Arg Cys Pro Gln Glu Met Phe Gln 
                85                  90                  95


Arg Met Glu Asp Thr Phe Arg Phe Cys Ala His Cys Arg Ala Leu Pro 
            100                 105                 110


Ser Gly Leu Ser Asp Ser Lys Val Leu Arg His Cys Lys Arg Cys Arg 
        115                 120                 125


Asn Val Tyr Tyr Cys Gly Pro Glu Cys Gln Lys Ser Asp Trp Pro Ala 
    130                 135                 140


His Arg Arg Val Cys Gln Glu Leu Arg Leu Val Ala Val Asp Arg Leu 
145                 150                 155                 160


Met Glu Trp Leu Leu Val Thr Gly Asp Phe Val Leu Pro Ser Gly Pro 
                165                 170                 175


Trp Pro Trp Pro Pro Glu Ala Val Gln Asp Trp Asp Ser Trp Phe Ser 
            180                 185                 190


Met Lys Gly Leu His Leu Asp Ala Thr Leu Asp Ala Val Leu Val Ser 
        195                 200                 205


His Ala Val Thr Thr Leu Trp Ala Ser Val Gly Arg Pro Arg Pro Asp 
    210                 215                 220


Pro Asp Val Leu Gln Gly Ser Leu Lys Arg Leu Leu Thr Asp Val Leu 
225                 230                 235                 240


Ser Arg Pro Leu Thr Leu Gly Leu Gly Leu Arg Ala Leu Gly Ile Asp 
                245                 250                 255


Val Arg Arg Thr Gly Gly Ser Thr Val His Val Val Gly Ala Ser His 
            260                 265                 270


Val Glu Thr Phe Leu Thr Arg Pro Gly Asp Tyr Asp Glu Leu Gly Tyr 
        275                 280                 285


Met Phe Pro Gly His Leu Gly Leu Arg Val Val Met Val Gly Val Asp 
    290                 295                 300


Val Ala Thr Gly Phe Ser Gln Ser Thr Ser Thr Ser Pro Leu Glu Pro 
305                 310                 315                 320


Gly Thr Ile Gln Leu Ser Ala His Arg Gly Leu Tyr His Asp Phe Trp 
                325                 330                 335


Glu Glu Gln Val Glu Thr Gly Gln Thr His His Pro Asp Leu Val Ala 
            340                 345                 350


Ala Phe His Pro Gly Phe His Ser Ser Pro Asp Leu Met Glu Ala Trp 
        355                 360                 365


Leu Pro Thr Leu Leu Leu Leu Arg Asp Tyr Lys Ile Pro Thr Leu Ile 
    370                 375                 380


Thr Val Tyr Ser His Gln Glu Leu Val Ser Ser Leu Gln Ile Leu Val 
385                 390                 395                 400


Glu Leu Asp Thr His Ile Thr Ala Phe Gly Ser Asn Pro Phe Met Ser 
                405                 410                 415


Leu Lys Pro Glu Gln Val Tyr Ser Ser Pro Asn Lys Gln Pro Val Tyr 
            420                 425                 430


Cys Ser Ala Tyr Tyr Ile Met Phe Leu Gly Ser Ser Cys Gln Leu Asp 
        435                 440                 445


Asn Arg Gln Leu Glu Glu Lys Val Asp Gly Gly Ile 
    450                 455                 460


<210>  7052
<211>  3547
<212>  DNA
<213>  Homo sapiens

<400>  7052
agggacagct gcaagtaagc cacaacctag atctgaagag atcaagcact catttcactt     60

ggaggaaaga gagaaggaag gaagctgagg acttagcagg gtatcactgg acaggccatg    120

gctccacggt cccggcgacg aaggcacaag aaacctccct catcagtggc tcccatcatc    180

atggccccaa ccacaattgt gacccctgtg cctctgaccc cctcaaaacc tggccctagc    240

attgacacac ttggcttctt ctccttggat gataatgttc ctggcctatc gcagctgatc    300

cttcaaaagc tgaacatgaa aagctatgaa gaatataagt tggtggtaga tgggggtacc    360

cccgtatcag gctttggatt tcgatgtcct caagaaatgt tccagaggat ggaagacaca    420

tttcgattct gtgctcactg tagagcactc cctagtgggc tttcagactc caaggttctc    480

cggcactgta agaggtgcag aaatgtctat tactgtggtc cagagtgcca gaagtcagac    540

tggcccgcac acaggagggt ttgtcaagag cttcgtcttg tggctgtgga ccgtctcatg    600

gaatggcttc tggtcacagg tggagtggtg gtgttgagga tctctgccat aatggtcata    660

gttgattgca tttaaaggaa gatacaaaat catattgtta tgaaaaaatg aggaagtggg    720

gcaaaggatg gggcacgcct gctcacaggt gattttgttc taccctcagg accttggcca    780

tggccacctg aagctgtaca ggactgggac tcctggtttt ctatgaaggg gttacaccta    840

gatgctacat tggatgctgt gctagttagt catgctgtga ccaccttatg ggccagtgta    900

ggacggccaa ggccagaccc ggatgtcctg cagggatctt tgaagcggct gctgacagat    960

gtcctgtcac ggcccttgac tctaggccta ggacttaggg ccttggggat agatgttagg   1020

aggactgggg gaagcacagt gcatgtggtt ggtgcttccc atgtggagac atttcttact   1080

cgcccagggg actatgatga gcttggttac atgtttcctg ggcaccttgg actccgtgtg   1140

gtcatggtgg gtgtagatgt agctactggc ttttcacaga gcacctcaac ttcacccctg   1200

gaacctggca caattcagct tagtgcccac aggggcctct accatgactt ctgggaggag   1260

caagtagaga ccgggcagac acaccatcca gatttggtgg cggcattcca tccaggtaag   1320

agtcattggt tcaggggaat agagggtggc tcccctgaga attttccatc ctgaatcttc   1380

tgtctttgga accccattca tttggtctca ttaaacacaa tatgatgaca acttttcttt   1440

tttttttttt cttttttttt ttttgagacg gagtctcgct ctgtcgccca ggctggagtg   1500

cagtggcgcg atctcggctc actgcaagct ccacctcccg ggttcacgcc attctcctgc   1560

ctcagcctcc cgagtagctg ggactacagg cgcctggcta attttttgta tttttagtag   1620

aggcggggtt tcactgtgtt agccacgatg atctcgatct cctgacctta tgatccgccc   1680

gcctctgcct cccaaagtgc tgggattaca ggcgtgagcc accgcgccca gcctgatgac   1740

aacttttctt gataatttgc catatgtact acacttgggt tcagaatttt tcattgaaga   1800

gtggatgatg atgatgatga taatgactgg ggataagcaa ggtgaggggt ggggtgctca   1860

cagtcaaaga aatatcttgc tcttagggtc tgctttagtc tttccctatt cccattttca   1920

tttttgttcc acaggttttc attcctcccc agacttgatg gaggcttggc tgcccaccct   1980

gctgctactt cgtgactata agattcctac attgattact gtttacaggt tttgacctca   2040

tcctatttgt gatacttccc tgactttaca tctctcttta tatagatgag ctcatttttg   2100

cccccctctt gctcatctac cttctggtga ggatgttctt ttccgcatat ggctttttta   2160

tccccttgga acagtccttt gctagttaat ggaatattta atgagacatt tgggagggaa   2220

agatagccct tgcctagtcc agccttaggc aatttggggg atgggtgatt acagaaatgt   2280

caggctcttg ggcagttttt cctttatctc tgtcacaatc agtagagtaa tttttcttct   2340

ctctcttcta cagccatcag gagttggtat cctctttgca gattctggtg gaactggata   2400

cacacatcac tgcctttggg tctaatcctt tcatgtccct caaacctgaa caggtctatt   2460

ccagtcccaa caagcagcca gtatactgca gtgcatacta tatcatgttt cttggaagct   2520

cctgtcagct ggataatagg caattagaag agaaagtgga cggcgggatt taaatagatc   2580

ataactggac atctggaaaa cggggagttt gtgatgaaat taccctgcta atgccaggtt   2640

cttgcaaact ttgaaaaaca ttatattcta aacctcattt actgtttggg taaaaattct   2700

aagctgaatg agagtttctg tataacataa ctggtttctt tctttttttg agatggagtc   2760

ttgctctgtt gcccaggctg gagtgcagcg gcatgatctc gactcactgc agcctccgcc   2820

tcctgggttc aagtggttct cctgcctcag cctccctagt agctgggatt acaggtgcac   2880

accaccacac ctggctaatt tttgtatttt tagcagacag ggtttcacca tgttggccag   2940

gctcgtatca aacccttgac cccaggtgat ctgcctgcct cagcctccca aagttctggg   3000

attacaggca tgagccacca tgcccagcca atgtaactgg tttctaagag tttagccaca   3060

gtagcttcta gagataggaa attagattta gtgggtggga agaggccctg atgctggtct   3120

ttccagagct tatagttgct aacacttttc tttgtaaaga agtttacctt ttgactggaa   3180

ccagatggca ctgagaaaaa gaatgagaac caccttattc ttctgaaaaa gactttcttc   3240

tcatccagta atttgggcta aaaaatggaa agatgttgat gacttgaagt gatgcaagaa   3300

tggacaagtc agggaagtca ttgggaacat ggatgaggtt gtaagcattg gtacagtgtc   3360

ctgtttcctg acttttttga gagaaatgtc tacttttcct gttttctctt ggggactttt   3420

gaccctagag tagccctggt gttatatttt agatatccca agctatatca gactttacct   3480

gaatatactg gagttactta ttatccccca ttctataccc caataaactc agtttggggc   3540

ttcttaa                                                             3547


<210>  7053
<211>  185
<212>  PRT
<213>  Homo sapiens

<400>  7053

Met Ala Pro Arg Ser Arg Arg Arg Arg His Lys Lys Pro Pro Ser Ser 
1               5                   10                  15


Val Ala Pro Ile Ile Met Ala Pro Thr Thr Ile Val Thr Pro Val Pro 
            20                  25                  30


Leu Thr Pro Ser Lys Pro Gly Pro Ser Ile Asp Thr Leu Gly Phe Phe 
        35                  40                  45


Ser Leu Asp Asp Asn Val Pro Gly Leu Ser Gln Leu Ile Leu Gln Lys 
    50                  55                  60


Leu Asn Met Lys Ser Tyr Glu Glu Tyr Lys Leu Val Val Asp Gly Gly 
65                  70                  75                  80


Thr Pro Val Ser Gly Phe Gly Phe Arg Cys Pro Gln Glu Met Phe Gln 
                85                  90                  95


Arg Met Glu Asp Thr Phe Arg Phe Cys Ala His Cys Arg Ala Leu Pro 
            100                 105                 110


Ser Gly Leu Ser Asp Ser Lys Val Leu Arg His Cys Lys Arg Cys Arg 
        115                 120                 125


Asn Val Tyr Tyr Cys Gly Pro Glu Cys Gln Lys Ser Asp Trp Pro Ala 
    130                 135                 140


His Arg Arg Val Cys Gln Glu Leu Arg Leu Val Ala Val Asp Arg Leu 
145                 150                 155                 160


Met Glu Trp Leu Leu Val Thr Gly Gly Val Val Val Leu Arg Ile Ser 
                165                 170                 175


Ala Ile Met Val Ile Val Asp Cys Ile 
            180                 185


<210>  7054
<211>  2313
<212>  DNA
<213>  Homo sapiens

<400>  7054
tatgggaagg atggaggggc caggaagata agtgacagaa atgttggtaa atgttctgag     60

tatttgctct gatgatgaac taatgactga aggtgaagac cagtttgatg gttcagctgc    120

agcccggaaa gaaatcataa gaaacaaaat tcgagcaatt ggcaagatgg caagagtctt    180

ctctgttctc agggaggaga gtgaaagtgt gctgacactc aagggcctga ctcccacagg    240

gatgttgcct agtggagtgt tagctggagg acggcagacc ctgcaaagtg ccacagttga    300

ggctattgag gctgaaaaag caatacgagg attctctcca ccacatagaa tctgcagttt    360

tgaagaggca aagggtttgg ataggatcaa tgagagaatg ccacctcgga aagatgctgt    420

acagcaagat ggtttcaatt ctctgaacac cgcacatgcc actgagaacc acgggacggg    480

caaccatact gcccagtgac ccactacttc ccagggactc tcacatctcg ggccccaaat    540

ggacagatca cccgaggagc tggaggggtc ggccaagctg actgtaaatt tcacagtctc    600

tctgaagaaa ccattgtgct tctgagaccc tagccccctt cctggatgga ggcttgaggg    660

ccctgggaca tgtgctatct gataagattg ggtcatcgct gccaaggtgg agagcagtga    720

gcaaggggct tggggcaatt tccagtggag ggcatccaca cctccatttt atgcttgtgg    780

ttcacacatt taagtttaca aatcagattt cttttcccct tcagtagaat tagattttgt    840

ttttcaatca tgatttcaaa tgcaatccta agagctaatg tggacttttc tttttccatg    900

aaatgtcttt aaaggatgaa ttagcatggt cttaaaatac atttctgagg ttactagctg    960

tattttgaat tgtgagcaaa atgccgagaa acccagttgg catttataca aaatgttgac   1020

ctcaggtcta tagttcttaa atgtggctaa ttctgtaaca tagtcttggt attttttaat   1080

tatgaatgca tatcctattt ccaggcaggc tctcttactt gaacacaaat ccaaaaacta   1140

atttagagtc ttttttgccc agatctttta agacttacac cccagagatt taagaagaaa   1200

acctctaaat ttcaaaatta tgaagaatta cagaattact catttaaggt actttaaaag   1260

aagtttgtac attgtcaaag taaattttaa ttcaaatcat gtctgtaaaa cttgacgtat   1320

tttgtgtatg catgttttca ttttgcaaat atttaatata tagacctatg atgtacaggt   1380

acgacatgta taggttacct agatgttatg agaaatttta gtttattgtg agtactcaag   1440

ttgcttagag agccaccagg gtgatttgct gctggctttc tatcattttt atgttttaat   1500

gcaaaggaaa ttttaaaatg ttctggaagt gtttttgatt aagcaatgca gcctagaagc   1560

aatggttctg ttcaatcatt cagatgttag tggaagcata aaagtcaaga ctgcatgttg   1620

aaacctttct tttgatagtt actgaactgc ttggttaaac taaatggaac catgtgctaa   1680

tttttcacaa ttattgacct gtattgattg ccactgtagt ttggtatttc cctttacttt   1740

ggtggcctgc ttccctcatg ccctggaata caactcagag ctccaggcag cggaaccatc   1800

tattgttttg tttgccagaa agtgcaccct gtatggtctc ctgtctaagt tggaaatatt   1860

atgcatgtgc aggactattc gagtatttta taaacagtag cacacaataa attccatgca   1920

tgggccgctg ctcctatctc tgtgttgggt tttatttgga agatgcaatc tgatttgtcc   1980

ttttgatgca aatcagaaaa tcctgttact agagctggga tgtcctccgg agattatctc   2040

gtggatagtt catggtaatt tgattaatta aattctttat aaattttgcc ttaaaaaaaa   2100

cttttgttat atacttgttt tacatgagca ttagtaactg agcactagag gactttgaat   2160

gcctactgta ggcctcctaa gtctaatatt taagatcact gtttattgtc ttttaattga   2220

aagaaaatat gttattgtct agaattttgt tatagtggta ttgggaattt actgggtgtt   2280

ctaacaataa gaaaaatatt agtgataatt gca                                2313


<210>  7055
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  7055

Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp Glu Leu Met Thr 
1               5                   10                  15


Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala Arg Lys Glu Ile 
            20                  25                  30


Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala Arg Val Phe Ser 
        35                  40                  45


Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu Lys Gly Leu Thr 
    50                  55                  60


Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly Gly Arg Gln Thr 
65                  70                  75                  80


Leu Gln Ser Ala Thr Val Glu Ala Ile Glu Ala Glu Lys Ala Ile Arg 
                85                  90                  95


Gly Phe Ser Pro Pro His Arg Ile Cys Ser Phe Glu Glu Ala Lys Gly 
            100                 105                 110


Leu Asp Arg Ile Asn Glu Arg Met Pro Pro Arg Lys Asp Ala Val Gln 
        115                 120                 125


Gln Asp Gly Phe Asn Ser Leu Asn Thr Ala His Ala Thr Glu Asn His 
    130                 135                 140


Gly Thr Gly Asn His Thr Ala Gln 
145                 150


<210>  7056
<211>  3524
<212>  DNA
<213>  Homo sapiens

<400>  7056
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagtgtg tcttatattt atgggttctg aagattctat acccaagcac attatttctt    600

ctgagaggca accatgaatg cagacacctt actgaatatt ttacctttaa gcaggaatgt    660

aaaattaagt attcggaaag agtctatgaa gcttgtatgg aagcttttga tagtttgcct    720

cttgctgcac ttttaaacca acagtttctt tgtgttcatg gtggactttc accagaaata    780

cacacactgg atgatattag gagattagat agattcaaag agccacctgc atttggacca    840

atgtgtgact tgttatggtc cgatccttct gaagattttg gaaatgaaaa atcacaggaa    900

cattttagtc acaatacagt tcgaggatgt tcttattttt ataactatcc agcagtgtgt    960

gaatttttgc aaaacaataa tttgttatcg attattagag ctcatgaagc tcaagatgca   1020

ggctatagaa tgtacagaaa aagtcaaact acagggttcc cttcattaat aacaattttt   1080

tcggcaccta attacttaga tgtctacaat aataaagctg ctgtattaaa gtatgaaaat   1140

aatgtgatga atattcgaca gtttaactgt tctccacatc cttactggtt gcctaatttt   1200

atggatgtct tcacgtggtc tttaccgttt gttggagaaa aagtgacaga aatgttggta   1260

aatgttctga gtatttgctc tgatgatgaa ctaatgactg aaggtgaaga ccagtttgat   1320

ggttcagctg cagcccggaa agaaatcata agaaacaaaa ttcgagcaat tggcaagatg   1380

gcaagagtct tctctgttct cagggaggag agtgaaagtg tgctgacact caagggcctg   1440

actcccacag ggatgttgcc tagtggagtg ttagctggag gacggcagac cctgcaaagt   1500

gccacagttg aggctattga ggctgaaaaa gcaatacgag gattctctcc accacataga   1560

atctgcagtt ttgaagaggc aaagggtttg gataggatca atgagagaat gccacctcgg   1620

aaagatgctg tacagcaaga tggtttcaat tctctgaaca ccgcacatgc cactgagaac   1680

cacgggacgg gcaaccatac tgcccagtga cccactactt cccagggact ctcacatctc   1740

gggccccaaa tggacagatc acccgaggag ctggaggggt cggccaagct gactgtaaat   1800

ttcacagtct ctctgaagaa accattgtgc ttctgagacc ctagccccct tcctggatgg   1860

aggcttgagg gccctgggac atgtgctatc tgataagatt gggtcatcgc tgccaaggtg   1920

gagagcagtg agcaaggggc ttggggcaat ttccagtgga gggcatccac acctccattt   1980

tatgcttgtg gttcacacat ttaagtttac aaatcagatt tcttttcccc ttcagtagaa   2040

ttagattttg tttttcaatc atgatttcaa atgcaatcct aagagctaat gtggactttt   2100

ctttttccat gaaatgtctt taaaggatga attagcatgg tcttaaaata catttctgag   2160

gttactagct gtattttgaa ttgtgagcaa aatgccgaga aacccagttg gcatttatac   2220

aaaatgttga cctcaggtct atagttctta aatgtggcta attctgtaac atagtcttgg   2280

tattttttaa ttatgaatgc atatcctatt tccaggcagg ctctcttact tgaacacaaa   2340

tccaaaaact aatttagagt cttttttgcc cagatctttt aagacttaca ccccagagat   2400

ttaagaagaa aacctctaaa tttcaaaatt atgaagaatt acagaattac tcatttaagg   2460

tactttaaaa gaagtttgta cattgtcaaa gtaaatttta attcaaatca tgtctgtaaa   2520

acttgacgta ttttgtgtat gcatgttttc attttgcaaa tatttaatat atagacctat   2580

gatgtacagg tacgacatgt ataggttacc tagatgttat gagaaatttt agtttattgt   2640

gagtactcaa gttgcttaga gagccaccag ggtgatttgc tgctggcttt ctatcatttt   2700

tatgttttaa tgcaaaggaa attttaaaat gttctggaag tgtttttgat taagcaatgc   2760

agcctagaag caatggttct gttcaatcat tcagatgtta gtggaagcat aaaagtcaag   2820

actgcatgtt gaaacctttc ttttgatagt tactgaactg cttggttaaa ctaaatggaa   2880

ccatgtgcta atttttcaca attattgacc tgtattgatt gccactgtag tttggtattt   2940

ccctttactt tggtggcctg cttccctcat gccctggaat acaactcaga gctccaggca   3000

gcggaaccat ctattgtttt gtttgccaga aagtgcaccc tgtatggtct cctgtctaag   3060

ttggaaatat tatgcatgtg caggactatt cgagtatttt ataaacagta gcacacaata   3120

aattccatgc atgggccgct gctcctatct ctgtgttggg ttttatttgg aagatgcaat   3180

ctgatttgtc cttttgatgc aaatcagaaa atcctgttac tagagctggg atgtcctccg   3240

gagattatct cgtggatagt tcatggtaat ttgattaatt aaattcttta taaattttgc   3300

cttaaaaaaa acttttgtta tatacttgtt ttacatgagc attagtaact gagcactaga   3360

ggactttgaa tgcctactgt aggcctccta agtctaatat ttaagatcac tgtttattgt   3420

cttttaattg aaagaaaata tgttattgtc tagaattttg ttatagtggt attgggaatt   3480

tactgggtgt tctaacaata agaaaaatat tagtgataat tgca                    3524


<210>  7057
<211>  524
<212>  PRT
<213>  Homo sapiens

<400>  7057

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Val 
    130                 135                 140


Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly Asn His 
145                 150                 155                 160


Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu Cys Lys 
                165                 170                 175


Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala Phe Asp 
            180                 185                 190


Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys Val His 
        195                 200                 205


Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg Arg Leu 
    210                 215                 220


Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp Leu Leu 
225                 230                 235                 240


Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln Glu His 
                245                 250                 255


Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn Tyr Pro 
            260                 265                 270


Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile Ile Arg 
        275                 280                 285


Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln 
    290                 295                 300


Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr 
305                 310                 315                 320


Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn 
                325                 330                 335


Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu 
            340                 345                 350


Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu 
        355                 360                 365


Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp 
    370                 375                 380


Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala 
385                 390                 395                 400


Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala 
                405                 410                 415


Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu 
            420                 425                 430


Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly 
        435                 440                 445


Gly Arg Gln Thr Leu Gln Ser Ala Thr Val Glu Ala Ile Glu Ala Glu 
    450                 455                 460


Lys Ala Ile Arg Gly Phe Ser Pro Pro His Arg Ile Cys Ser Phe Glu 
465                 470                 475                 480


Glu Ala Lys Gly Leu Asp Arg Ile Asn Glu Arg Met Pro Pro Arg Lys 
                485                 490                 495


Asp Ala Val Gln Gln Asp Gly Phe Asn Ser Leu Asn Thr Ala His Ala 
            500                 505                 510


Thr Glu Asn His Gly Thr Gly Asn His Thr Ala Gln 
        515                 520


<210>  7058
<211>  3494
<212>  DNA
<213>  Homo sapiens

<400>  7058
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagtgtg tcttatattt atgggttctg aagattctat acccaagcac attatttctt    600

ctgagaggca accatgaatg cagacacctt actgaatatt ttacctttaa gcaggaatgt    660

aaaattaagt attcggaaag agtctatgaa gcttgtatgg aagcttttga tagtttgcct    720

cttgctgcac ttttaaacca acagtttctt tgtgttcatg gtggactttc accagaaata    780

cacacactgg atgatattag gagattagat agattcaaag agccacctgc atttggacca    840

atgtgtgact tgttatggtc cgatccttct gaagattttg gaaatgaaaa atcacaggaa    900

cattttagtc acaatacagt tcgaggatgt tcttattttt ataactatcc agcagtgtgt    960

gaatttttgc aaaacaataa tttgttatcg attattagag ctcatgaagc tcaagatgca   1020

ggctatagaa tgtacagaaa aagtcaaact acagggttcc cttcattaat aacaattttt   1080

tcggcaccta attacttaga tgtctacaat aataaagctg ctgtattaaa gtatgaaaat   1140

aatgtgatga atattcgaca gtttaactgt tctccacatc cttactggtt gcctaatttt   1200

atggatgtct tcacgtggtc tttaccgttt gttggagaaa aagtgacaga aatgttggta   1260

aatgttctga gtatttgctc tgatgatgaa ctaatgactg aaggtgaaga ccagtttgat   1320

ggttcagctg cagcccggaa agaaatcata agaaacaaaa ttcgagcaat tggcaagatg   1380

gcaagagtct tctctgttct cagggaggag agtgaaagtg tgctgacact caagggcctg   1440

actcccacag ggatgttgcc tagtggagtg ttagctggag gacggcagac cctgcaaagt   1500

gcaatacgag gattctctcc accacataga atctgcagtt ttgaagaggc aaagggtttg   1560

gataggatca atgagagaat gccacctcgg aaagatgctg tacagcaaga tggtttcaat   1620

tctctgaaca ccgcacatgc cactgagaac cacgggacgg gcaaccatac tgcccagtga   1680

cccactactt cccagggact ctcacatctc gggccccaaa tggacagatc acccgaggag   1740

ctggaggggt cggccaagct gactgtaaat ttcacagtct ctctgaagaa accattgtgc   1800

ttctgagacc ctagccccct tcctggatgg aggcttgagg gccctgggac atgtgctatc   1860

tgataagatt gggtcatcgc tgccaaggtg gagagcagtg agcaaggggc ttggggcaat   1920

ttccagtgga gggcatccac acctccattt tatgcttgtg gttcacacat ttaagtttac   1980

aaatcagatt tcttttcccc ttcagtagaa ttagattttg tttttcaatc atgatttcaa   2040

atgcaatcct aagagctaat gtggactttt ctttttccat gaaatgtctt taaaggatga   2100

attagcatgg tcttaaaata catttctgag gttactagct gtattttgaa ttgtgagcaa   2160

aatgccgaga aacccagttg gcatttatac aaaatgttga cctcaggtct atagttctta   2220

aatgtggcta attctgtaac atagtcttgg tattttttaa ttatgaatgc atatcctatt   2280

tccaggcagg ctctcttact tgaacacaaa tccaaaaact aatttagagt cttttttgcc   2340

cagatctttt aagacttaca ccccagagat ttaagaagaa aacctctaaa tttcaaaatt   2400

atgaagaatt acagaattac tcatttaagg tactttaaaa gaagtttgta cattgtcaaa   2460

gtaaatttta attcaaatca tgtctgtaaa acttgacgta ttttgtgtat gcatgttttc   2520

attttgcaaa tatttaatat atagacctat gatgtacagg tacgacatgt ataggttacc   2580

tagatgttat gagaaatttt agtttattgt gagtactcaa gttgcttaga gagccaccag   2640

ggtgatttgc tgctggcttt ctatcatttt tatgttttaa tgcaaaggaa attttaaaat   2700

gttctggaag tgtttttgat taagcaatgc agcctagaag caatggttct gttcaatcat   2760

tcagatgtta gtggaagcat aaaagtcaag actgcatgtt gaaacctttc ttttgatagt   2820

tactgaactg cttggttaaa ctaaatggaa ccatgtgcta atttttcaca attattgacc   2880

tgtattgatt gccactgtag tttggtattt ccctttactt tggtggcctg cttccctcat   2940

gccctggaat acaactcaga gctccaggca gcggaaccat ctattgtttt gtttgccaga   3000

aagtgcaccc tgtatggtct cctgtctaag ttggaaatat tatgcatgtg caggactatt   3060

cgagtatttt ataaacagta gcacacaata aattccatgc atgggccgct gctcctatct   3120

ctgtgttggg ttttatttgg aagatgcaat ctgatttgtc cttttgatgc aaatcagaaa   3180

atcctgttac tagagctggg atgtcctccg gagattatct cgtggatagt tcatggtaat   3240

ttgattaatt aaattcttta taaattttgc cttaaaaaaa acttttgtta tatacttgtt   3300

ttacatgagc attagtaact gagcactaga ggactttgaa tgcctactgt aggcctccta   3360

agtctaatat ttaagatcac tgtttattgt cttttaattg aaagaaaata tgttattgtc   3420

tagaattttg ttatagtggt attgggaatt tactgggtgt tctaacaata agaaaaatat   3480

tagtgataat tgca                                                     3494


<210>  7059
<211>  514
<212>  PRT
<213>  Homo sapiens

<400>  7059

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Val 
    130                 135                 140


Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly Asn His 
145                 150                 155                 160


Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu Cys Lys 
                165                 170                 175


Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala Phe Asp 
            180                 185                 190


Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys Val His 
        195                 200                 205


Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg Arg Leu 
    210                 215                 220


Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp Leu Leu 
225                 230                 235                 240


Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln Glu His 
                245                 250                 255


Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn Tyr Pro 
            260                 265                 270


Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile Ile Arg 
        275                 280                 285


Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln 
    290                 295                 300


Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr 
305                 310                 315                 320


Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn 
                325                 330                 335


Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu 
            340                 345                 350


Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu 
        355                 360                 365


Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp 
    370                 375                 380


Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala 
385                 390                 395                 400


Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala 
                405                 410                 415


Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu 
            420                 425                 430


Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly 
        435                 440                 445


Gly Arg Gln Thr Leu Gln Ser Ala Ile Arg Gly Phe Ser Pro Pro His 
    450                 455                 460


Arg Ile Cys Ser Phe Glu Glu Ala Lys Gly Leu Asp Arg Ile Asn Glu 
465                 470                 475                 480


Arg Met Pro Pro Arg Lys Asp Ala Val Gln Gln Asp Gly Phe Asn Ser 
                485                 490                 495


Leu Asn Thr Ala His Ala Thr Glu Asn His Gly Thr Gly Asn His Thr 
            500                 505                 510


Ala Gln 



<210>  7060
<211>  1935
<212>  DNA
<213>  Homo sapiens

<400>  7060
tatgggaagg atggaggggc caggaagata agtgacagaa atgttggtaa atgttctgag     60

tatttgctct gatgatgaac taatgactga aggtgaagac cagtttgatg gttcagctgc    120

agcccggaaa gaaatcataa gaaacaaaat tcgagcaatt ggcaagatgg caagagtctt    180

ctctgttctc agggaggaga gtgaaagtgt gctgacactc aagggcctga ctcccacagg    240

gatgttgcct agtggagtgt tagctggagg acggcagacc ctgcaaagtg ccacagttga    300

ggctattgag gctgaaaaag caatacgagg attctctcca ccacatagaa tctgcagttt    360

tgaagaggca aagggtttgg ataggatcaa tgagagaatg ccacctcgga aagatgctgt    420

acagcaagat ggtttcaatt ctctgaacac cgcacatgcc actgagaacc acgggacggg    480

caaccatact gcccagtgac ccactacttc ccagggactc tcacatctcg ggccccaaat    540

ggacagatca cccgaggagc tggaggggtc ggccaagctg actgtaaatt tcacagtctc    600

tctgaagaaa ccattgtgct tctgagaccc tagccccctt cctggatgga ggcttgaggg    660

ccctgggaca tgtgctatct gataagattg ggtcatcgct gccaaggtgg agagcagtga    720

gcaaggggct tggggcaatt tccagtggag ggcatccaca cctccatttt atgcttgtgg    780

ttcacacatt taagtttaca aatcagattt cttttcccct tcagtagaat tagattttgt    840

ttttcaatca tgatttcaaa tgcaatccta agagctaatg tggacttttc tttttccatg    900

aaatgtcttt aaaggatgaa ttagcatggt cttaaaatac atttctgagg ttactagctg    960

tattttgaat tgtgagcaaa atgccgagaa acccagttgg catttataca aaatgttgac   1020

ctcaggtcta tagttcttaa atgtggctaa ttctgtaaca tagtcttggt attttttaat   1080

tatgaatgca tatcctattt ccaggcaggc tctcttactt gaacacaaat ccaaaaacta   1140

atttagagtc ttttttgccc agatctttta agacttacac cccagagatt taagaagaaa   1200

acctctaaat ttcaaaatta tgaagaatta cagaattact catttaaggt actttaaaag   1260

aagtttgtac attgtcaaag taaattttaa ttcaaatcat gtctgtaaaa cttgacgtat   1320

tttgtgtatg catgttttca ttttgcaaat atttaatata tagacctatg atgtacaggt   1380

acgacatgta taggttacct agatgttatg agaaatttta gtttattgtg agtactcaag   1440

ttgcttagag agccaccagg gtgatttgct gctggctttc tatcattttt atgttttaat   1500

gcaaaggaaa ttttaaaatg ttctggaagt gtttttgatt aagcaatgca gcctagaagc   1560

aatggttctg ttcaatcatt cagatgttag tggaagcata aaagtcaaga ctgcatgttg   1620

aaacctttct tttgatagtt actgaactgc ttggttaaac taaatggaac catgtgctaa   1680

tttttcacaa ttattgacct gtattgattg ccactgtagt ttggtatttc cctttacttt   1740

ggtggcctgc ttccctcatg ccctggaata caactcagag ctccaggcag cggaaccatc   1800

tattgttttg tttgccagaa agtgcaccct gtatggtctc ctgtctaagt tggaaatatt   1860

atgcatgtgc aggactattc gagtatttta taaacagtag cacacaataa attccatgca   1920

tgggccgctg ctcct                                                    1935


<210>  7061
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  7061

Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp Glu Leu Met Thr 
1               5                   10                  15


Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala Arg Lys Glu Ile 
            20                  25                  30


Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala Arg Val Phe Ser 
        35                  40                  45


Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu Lys Gly Leu Thr 
    50                  55                  60


Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly Gly Arg Gln Thr 
65                  70                  75                  80


Leu Gln Ser Ala Thr Val Glu Ala Ile Glu Ala Glu Lys Ala Ile Arg 
                85                  90                  95


Gly Phe Ser Pro Pro His Arg Ile Cys Ser Phe Glu Glu Ala Lys Gly 
            100                 105                 110


Leu Asp Arg Ile Asn Glu Arg Met Pro Pro Arg Lys Asp Ala Val Gln 
        115                 120                 125


Gln Asp Gly Phe Asn Ser Leu Asn Thr Ala His Ala Thr Glu Asn His 
    130                 135                 140


Gly Thr Gly Asn His Thr Ala Gln 
145                 150


<210>  7062
<211>  3116
<212>  DNA
<213>  Homo sapiens

<400>  7062
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagtgtg tcttatattt atgggttctg aagattctat acccaagcac attatttctt    600

ctgagaggca accatgaatg cagacacctt actgaatatt ttacctttaa gcaggaatgt    660

aaaattaagt attcggaaag agtctatgaa gcttgtatgg aagcttttga tagtttgcct    720

cttgctgcac ttttaaacca acagtttctt tgtgttcatg gtggactttc accagaaata    780

cacacactgg atgatattag gagattagat agattcaaag agccacctgc atttggacca    840

atgtgtgact tgttatggtc cgatccttct gaagattttg gaaatgaaaa atcacaggaa    900

cattttagtc acaatacagt tcgaggatgt tcttattttt ataactatcc agcagtgtgt    960

gaatttttgc aaaacaataa tttgttatcg attattagag ctcatgaagc tcaagatgca   1020

ggctatagaa tgtacagaaa aagtcaaact acagggttcc cttcattaat aacaattttt   1080

tcggcaccta attacttaga tgtctacaat aataaagctg ctgtattaaa gtatgaaaat   1140

aatgtgatga atattcgaca gtttaactgt tctccacatc cttactggtt gcctaatttt   1200

atggatgtct tcacgtggtc tttaccgttt gttggagaaa aagtgacaga aatgttggta   1260

aatgttctga gtatttgctc tgatgatgaa ctaatgactg aaggtgaaga ccagtttgat   1320

ggttcagctg cagcccggaa agaaatcata agaaacaaaa ttcgagcaat tggcaagatg   1380

gcaagagtct tctctgttct cagggaggag agtgaaagtg tgctgacact caagggcctg   1440

actcccacag ggatgttgcc tagtggagtg ttagctggag gacggcagac cctgcaaagt   1500

gcaatacgag gattctctcc accacataga atctgcagtt ttgaagaggc aaagggtttg   1560

gataggatca atgagagaat gccacctcgg aaagatgctg tacagcaaga tggtttcaat   1620

tctctgaaca ccgcacatgc cactgagaac cacgggacgg gcaaccatac tgcccagtga   1680

cccactactt cccagggact ctcacatctc gggccccaaa tggacagatc acccgaggag   1740

ctggaggggt cggccaagct gactgtaaat ttcacagtct ctctgaagaa accattgtgc   1800

ttctgagacc ctagccccct tcctggatgg aggcttgagg gccctgggac atgtgctatc   1860

tgataagatt gggtcatcgc tgccaaggtg gagagcagtg agcaaggggc ttggggcaat   1920

ttccagtgga gggcatccac acctccattt tatgcttgtg gttcacacat ttaagtttac   1980

aaatcagatt tcttttcccc ttcagtagaa ttagattttg tttttcaatc atgatttcaa   2040

atgcaatcct aagagctaat gtggactttt ctttttccat gaaatgtctt taaaggatga   2100

attagcatgg tcttaaaata catttctgag gttactagct gtattttgaa ttgtgagcaa   2160

aatgccgaga aacccagttg gcatttatac aaaatgttga cctcaggtct atagttctta   2220

aatgtggcta attctgtaac atagtcttgg tattttttaa ttatgaatgc atatcctatt   2280

tccaggcagg ctctcttact tgaacacaaa tccaaaaact aatttagagt cttttttgcc   2340

cagatctttt aagacttaca ccccagagat ttaagaagaa aacctctaaa tttcaaaatt   2400

atgaagaatt acagaattac tcatttaagg tactttaaaa gaagtttgta cattgtcaaa   2460

gtaaatttta attcaaatca tgtctgtaaa acttgacgta ttttgtgtat gcatgttttc   2520

attttgcaaa tatttaatat atagacctat gatgtacagg tacgacatgt ataggttacc   2580

tagatgttat gagaaatttt agtttattgt gagtactcaa gttgcttaga gagccaccag   2640

ggtgatttgc tgctggcttt ctatcatttt tatgttttaa tgcaaaggaa attttaaaat   2700

gttctggaag tgtttttgat taagcaatgc agcctagaag caatggttct gttcaatcat   2760

tcagatgtta gtggaagcat aaaagtcaag actgcatgtt gaaacctttc ttttgatagt   2820

tactgaactg cttggttaaa ctaaatggaa ccatgtgcta atttttcaca attattgacc   2880

tgtattgatt gccactgtag tttggtattt ccctttactt tggtggcctg cttccctcat   2940

gccctggaat acaactcaga gctccaggca gcggaaccat ctattgtttt gtttgccaga   3000

aagtgcaccc tgtatggtct cctgtctaag ttggaaatat tatgcatgtg caggactatt   3060

cgagtatttt ataaacagta gcacacaata aattccatgc atgggccgct gctcct       3116


<210>  7063
<211>  514
<212>  PRT
<213>  Homo sapiens

<400>  7063

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Val 
    130                 135                 140


Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly Asn His 
145                 150                 155                 160


Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu Cys Lys 
                165                 170                 175


Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala Phe Asp 
            180                 185                 190


Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys Val His 
        195                 200                 205


Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg Arg Leu 
    210                 215                 220


Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp Leu Leu 
225                 230                 235                 240


Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln Glu His 
                245                 250                 255


Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn Tyr Pro 
            260                 265                 270


Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile Ile Arg 
        275                 280                 285


Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln 
    290                 295                 300


Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr 
305                 310                 315                 320


Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn 
                325                 330                 335


Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu 
            340                 345                 350


Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu 
        355                 360                 365


Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp 
    370                 375                 380


Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala 
385                 390                 395                 400


Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala 
                405                 410                 415


Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu 
            420                 425                 430


Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly 
        435                 440                 445


Gly Arg Gln Thr Leu Gln Ser Ala Ile Arg Gly Phe Ser Pro Pro His 
    450                 455                 460


Arg Ile Cys Ser Phe Glu Glu Ala Lys Gly Leu Asp Arg Ile Asn Glu 
465                 470                 475                 480


Arg Met Pro Pro Arg Lys Asp Ala Val Gln Gln Asp Gly Phe Asn Ser 
                485                 490                 495


Leu Asn Thr Ala His Ala Thr Glu Asn His Gly Thr Gly Asn His Thr 
            500                 505                 510


Ala Gln 



<210>  7064
<211>  3146
<212>  DNA
<213>  Homo sapiens

<400>  7064
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagtgtg tcttatattt atgggttctg aagattctat acccaagcac attatttctt    600

ctgagaggca accatgaatg cagacacctt actgaatatt ttacctttaa gcaggaatgt    660

aaaattaagt attcggaaag agtctatgaa gcttgtatgg aagcttttga tagtttgcct    720

cttgctgcac ttttaaacca acagtttctt tgtgttcatg gtggactttc accagaaata    780

cacacactgg atgatattag gagattagat agattcaaag agccacctgc atttggacca    840

atgtgtgact tgttatggtc cgatccttct gaagattttg gaaatgaaaa atcacaggaa    900

cattttagtc acaatacagt tcgaggatgt tcttattttt ataactatcc agcagtgtgt    960

gaatttttgc aaaacaataa tttgttatcg attattagag ctcatgaagc tcaagatgca   1020

ggctatagaa tgtacagaaa aagtcaaact acagggttcc cttcattaat aacaattttt   1080

tcggcaccta attacttaga tgtctacaat aataaagctg ctgtattaaa gtatgaaaat   1140

aatgtgatga atattcgaca gtttaactgt tctccacatc cttactggtt gcctaatttt   1200

atggatgtct tcacgtggtc tttaccgttt gttggagaaa aagtgacaga aatgttggta   1260

aatgttctga gtatttgctc tgatgatgaa ctaatgactg aaggtgaaga ccagtttgat   1320

ggttcagctg cagcccggaa agaaatcata agaaacaaaa ttcgagcaat tggcaagatg   1380

gcaagagtct tctctgttct cagggaggag agtgaaagtg tgctgacact caagggcctg   1440

actcccacag ggatgttgcc tagtggagtg ttagctggag gacggcagac cctgcaaagt   1500

gccacagttg aggctattga ggctgaaaaa gcaatacgag gattctctcc accacataga   1560

atctgcagtt ttgaagaggc aaagggtttg gataggatca atgagagaat gccacctcgg   1620

aaagatgctg tacagcaaga tggtttcaat tctctgaaca ccgcacatgc cactgagaac   1680

cacgggacgg gcaaccatac tgcccagtga cccactactt cccagggact ctcacatctc   1740

gggccccaaa tggacagatc acccgaggag ctggaggggt cggccaagct gactgtaaat   1800

ttcacagtct ctctgaagaa accattgtgc ttctgagacc ctagccccct tcctggatgg   1860

aggcttgagg gccctgggac atgtgctatc tgataagatt gggtcatcgc tgccaaggtg   1920

gagagcagtg agcaaggggc ttggggcaat ttccagtgga gggcatccac acctccattt   1980

tatgcttgtg gttcacacat ttaagtttac aaatcagatt tcttttcccc ttcagtagaa   2040

ttagattttg tttttcaatc atgatttcaa atgcaatcct aagagctaat gtggactttt   2100

ctttttccat gaaatgtctt taaaggatga attagcatgg tcttaaaata catttctgag   2160

gttactagct gtattttgaa ttgtgagcaa aatgccgaga aacccagttg gcatttatac   2220

aaaatgttga cctcaggtct atagttctta aatgtggcta attctgtaac atagtcttgg   2280

tattttttaa ttatgaatgc atatcctatt tccaggcagg ctctcttact tgaacacaaa   2340

tccaaaaact aatttagagt cttttttgcc cagatctttt aagacttaca ccccagagat   2400

ttaagaagaa aacctctaaa tttcaaaatt atgaagaatt acagaattac tcatttaagg   2460

tactttaaaa gaagtttgta cattgtcaaa gtaaatttta attcaaatca tgtctgtaaa   2520

acttgacgta ttttgtgtat gcatgttttc attttgcaaa tatttaatat atagacctat   2580

gatgtacagg tacgacatgt ataggttacc tagatgttat gagaaatttt agtttattgt   2640

gagtactcaa gttgcttaga gagccaccag ggtgatttgc tgctggcttt ctatcatttt   2700

tatgttttaa tgcaaaggaa attttaaaat gttctggaag tgtttttgat taagcaatgc   2760

agcctagaag caatggttct gttcaatcat tcagatgtta gtggaagcat aaaagtcaag   2820

actgcatgtt gaaacctttc ttttgatagt tactgaactg cttggttaaa ctaaatggaa   2880

ccatgtgcta atttttcaca attattgacc tgtattgatt gccactgtag tttggtattt   2940

ccctttactt tggtggcctg cttccctcat gccctggaat acaactcaga gctccaggca   3000

gcggaaccat ctattgtttt gtttgccaga aagtgcaccc tgtatggtct cctgtctaag   3060

ttggaaatat tatgcatgtg caggactatt cgagtatttt ataaacagta gcacacaata   3120

aattccatgc atgggccgct gctcct                                        3146


<210>  7065
<211>  524
<212>  PRT
<213>  Homo sapiens

<400>  7065

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu Cys Val Leu Tyr Leu Trp Val 
    130                 135                 140


Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly Asn His 
145                 150                 155                 160


Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu Cys Lys 
                165                 170                 175


Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala Phe Asp 
            180                 185                 190


Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys Val His 
        195                 200                 205


Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg Arg Leu 
    210                 215                 220


Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp Leu Leu 
225                 230                 235                 240


Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln Glu His 
                245                 250                 255


Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn Tyr Pro 
            260                 265                 270


Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile Ile Arg 
        275                 280                 285


Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys Ser Gln 
    290                 295                 300


Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro Asn Tyr 
305                 310                 315                 320


Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu Asn Asn 
                325                 330                 335


Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr Trp Leu 
            340                 345                 350


Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val Gly Glu 
        355                 360                 365


Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser Asp Asp 
    370                 375                 380


Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala Ala Ala 
385                 390                 395                 400


Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys Met Ala 
                405                 410                 415


Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu Thr Leu 
            420                 425                 430


Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu Ala Gly 
        435                 440                 445


Gly Arg Gln Thr Leu Gln Ser Ala Thr Val Glu Ala Ile Glu Ala Glu 
    450                 455                 460


Lys Ala Ile Arg Gly Phe Ser Pro Pro His Arg Ile Cys Ser Phe Glu 
465                 470                 475                 480


Glu Ala Lys Gly Leu Asp Arg Ile Asn Glu Arg Met Pro Pro Arg Lys 
                485                 490                 495


Asp Ala Val Gln Gln Asp Gly Phe Asn Ser Leu Asn Thr Ala His Ala 
            500                 505                 510


Thr Glu Asn His Gly Thr Gly Asn His Thr Ala Gln 
        515                 520


<210>  7066
<211>  3691
<212>  DNA
<213>  Homo sapiens

<400>  7066
gtttatatat ttgtatactg aagatgggaa cacaagtccc tttgaagcta agatttttga     60

ctctggtgat tgttattgct catctttggt atctcttttc cgtttgtgat aacactaaat    120

tcacaccttg aaaattagag caggataaga aggaggggat actttttaga gtattcttga    180

tgaacttgtt catccatata ggaagtccct tgtgctggag ccataaattg ccttccctgg    240

ggttaattca ggaagaccag gttaaagggt acaaatgaat aggtcagtct ttaaaaattt    300

gtttgcacaa ctgactacat cagacatttg aacttcagag catatgaaat accatatttt    360

ctcaatagta tgatgcccct tgatgaatct taccacatat ttaataaagc ttttcaggaa    420

aaacaatata tgcctcaatg gtaaggcaca ccctcatacc tgaaacactt aaaatataga    480

aaaattaatg tcttgaaatt gaggaaaata tggtaatagc aatgaatgtc atgaatttta    540

tatatggcct atatctagac cctatgtctt cttttaaatt aagtacttgt tggaagtatc    600

tgatatttgt tatatctctc tgctataggg aggagagtga aagtgtgctg acactcaagg    660

gcctgactcc cacagggatg ttgcctagtg gagtgttagc tggaggacgg cagaccctgc    720

aaagtggtaa tgatgttatg caacttgctg tgcctcagat ggactggggc acacctcact    780

cttttgctaa caattcacat aatgcatgca gggaattcct tctgtttttt agttcctgtc    840

tcagcagctg acctagacag ggtactgtat tagctagtgt ctcattaata cctgatcagg    900

gcagaaaact gatagaatgg gtattccttt caattgaaaa taatggtcag ttcctcagct    960

tttcatgaaa tgatatggga gcagctcata tcataatgtc tgaaatattt atttattcat   1020

ctgtctaatt cacccttttc ttttaaaagc cccagtttca gaatgtgaat cagggatatt   1080

cctgttacta aaatggaaat gtaattccaa gtttcttttt taatttttta aatttatgtc   1140

attgtattgg actatgctta tatttaaaac tacttaattt agagttaact acctgcttag   1200

gccccagaac attacttatg cccttcagtt accaaaagat ttgtgcaagg ttttgtaccc   1260

tggtaaatga tgccaaagtt tgttttctgt ggtgtttgtc aaatgttcta tgtataatta   1320

actgtctgta acatgctgtt tccttcctct gcagatgtag ctgctttcct aaatctgtct   1380

gtctttcttt aggttagctg tatgtctgta aaagtatgtt caattaaatt actccatcag   1440

acacttgtct gtcttgcaat gtagaagcag ctttgtagca ccttgttttg aggtttgctg   1500

catttgttgc tgcactttgt gcattctgaa catgaatgta acattagata ttaagtcatt   1560

gttataaggg gttgaattta aatcctgtaa gtcaaaattg aaagggtgtt attaagtgtg   1620

cctttatttt gcatgaaaat aaaaagaatt atacgtaaag cattcctgta atctggctca   1680

ttgaatattt tatacttaaa aaactttttt tggcgtaaat atttgtgtaa atactgggtt   1740

aactttttaa aagcccatta cagattaaat agaagagagt gatgtgagta ttagtgacca   1800

tacacagtaa ttcagtctag atttcttttc ctgtggttgg aaagcaaaaa tacatgatgt   1860

ggaaaagcct gaatttcttg tagtcacttt tgacagccct ctaagggtca ttgtctatta   1920

aaatagcaac agatctgatg ttttccttag tcataattag gtttcttttt ggtgttgtaa   1980

ttagtgactt ttttagaggg aaaaaaatag gcaattttaa cgttttgaat gaatttacat   2040

ttgacttcac aatttcattt cacttggttc cataataagt gcgtgtgcat gtgtacatgt   2100

gtgtgtgtga gagagacaat gattgctttt caataaaaaa aatttttttc ctgtaaacaa   2160

tttttacttg tagcctatac atgttctatt ttaaatgtca ttgtattgtt cactaccacc   2220

actggtatat ctgaaaagta cactgtgttt tgaaattata aattttcatt ctgaatgagg   2280

tttctttttt tgattttctt taaaaaaaaa aaacaacctg ctttgatttg ctttacattc   2340

cttgccctcc atttttctta ttatattgta aacattagaa aaatgaacta aaaagaattt   2400

catgaatgta cattaaaaca agatcttaaa catttgataa aactagtaaa aatgttaata   2460

gaaaaggatg aactttaata gcttcaaaaa tattatactc ttctttgttc agaaaagaaa   2520

aataaaacca aaagggtatc atacttaaat aaatctacag tatagtcatc tctcagttat   2580

ccttggatat aacattactt ttatattgta tccgcagcaa accttgcttt cagatttcac   2640

gattagcccc tgctaattac atgctttgtt gacttctgtt tattcttaat ttgtacacgg   2700

cttgaagctc attccttcaa ctttgaaacc accctcaact gcaggggagg tttgaaagac   2760

agcagctttg ctggagggac tctctattct cagcatggac taagttactg gaaggaattg   2820

agtttaaggg gtctaatttg ggacccctta aactagatag cttctagttt tgctagctct   2880

tgatagtgtg gtttgggcat ttggtcaaaa ttattttcct agcataagat aaatccactt   2940

tgaaacaaat aacaaaggtc atacaaaagc tgcatgtttg tgattatttt ttaaaaagtt   3000

atcctacatt ttaaatttta gtagataatg ttccctgatg ttagtgtgta taactgagag   3060

ttaggtattg caaaaggaaa aaattttaat tctaagacct cgtgcctatt tgtcagaaaa   3120

taaaaattgt cgtttcaaga actttaaaag ttaatttaca tgatgtttct tgagtgtttt   3180

tacaaactgc acaactctat tggaggtgga ttttctgttc atctttattt tatgtatgtt   3240

ttctttctgg gaaatttgat tgggagctag cactgtaatg ctaccctcac caggatctat   3300

atgggaaata tatgtggcca attctatgtt agtaatacca aattcctctt ggtcatttat   3360

cttgcatagt actgaggaac acagtttgag atagcactat gctcaaactt attaaggcca   3420

tgacaagatg ccctatataa ctgaaaacaa atagaggaga aatagtgcct ttcagataga   3480

gtgttgcaat tagcaatctg ggctcaagtg atcttcctgc ttcagcttcc cgagtagctg   3540

ggattacata tgcacaccac catgcccggc taatttttta aacttttttt ggggggagat   3600

gaggtctctc tatgtgttgc ccaggctggg ctcaaacgct caagggatcc ttccacctca   3660

gccatccgag agtgctgggg ttataggcat g                                  3691


<210>  7067
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  7067

Met Asn Leu His Leu Thr Ser Gln Phe His Phe Thr Trp Phe His Asn 
1               5                   10                  15


Lys Cys Val Cys Met Cys Thr Cys Val Cys Val Arg Glu Thr Met Ile 
            20                  25                  30


Ala Phe Gln 
        35


<210>  7068
<211>  2595
<212>  DNA
<213>  Homo sapiens

<400>  7068
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagcatg ttctaggcac tgaagacata tcgattaatc ctcacaataa tattaatgag    600

tgtgtcttat atttatgggt tctgaagatt ctatacccaa gcacattatt tcttctgaga    660

ggcaaccatg aatgcagaca ccttactgaa tattttacct ttaagcagga atgtaaaatt    720

aagtattcgg aaagagtcta tgaagcttgt atggaagctt ttgatagttt gcctcttgct    780

gcacttttaa accaacagtt tctttgtgtt catggtggac tttcaccaga aatacacaca    840

ctggatgata ttaggagatt agatagattc aaagagccac ctgcatttgg accaatgtgt    900

gacttgttat ggtccgatcc ttctgaagat tttggaaatg aaaaatcaca ggaacatttt    960

agtcacaata cagttcgagg atgttcttat ttttataact atccagcagt gtgtgaattt   1020

ttgcaaaaca ataatttgtt atcgattatt agagctcatg aagctcaaga tgcaggctat   1080

agaatgtaca gaaaaagtca aactacaggg ttcccttcat taataacaat tttttcggca   1140

cctaattact tagatgtcta caataataaa gctgctgtat taaagtatga aaataatgtg   1200

atgaatattc gacagtttaa ctgttctcca catccttact ggttgcctaa ttttatggat   1260

gtcttcacgt ggtctttacc gtttgttgga gaaaaagtga cagaaatgtt ggtaaatgtt   1320

ctgagtattt gctctgatga tgaactaatg actgaaggtg aagaccagtt tgatggttca   1380

gctgcagccc ggaaagaaat cataagaaac aaaattcgag caattggcaa gatggcaaga   1440

gtcttctctg ttctcaggga ggagagtgaa agtgtgctga cactcaaggg cctgactccc   1500

acagggatgt tgcctagtgg agtgttagct ggaggacggc agaccctgca aagtggtaat   1560

gatgttatgc aacttgctgt gcctcagatg gactggggca cacctcactc ttttgctaac   1620

aattcacata atgcatgcag ggaattcctt ctgtttttta gttcctgtct cagcagctga   1680

cctagacagg gtactgtatt agctagtgtc tcattaatac ctgatcaggg cagaaaactg   1740

atagaatggg tattcctttc aattgaaaat aatggtcagt tcctcagctt ttcatgaaat   1800

gatatgggag cagctcatat cataatgtct gaaatattta tttattcatc tgtctaattc   1860

acccttttct tttaaaagcc ccagtttcag aatgtgaatc agggatattc ctgttactaa   1920

aatggaaatg taattccaag tttctttttt aattttttaa atttatgtca ttgtattgga   1980

ctatgcttat atttaaaact acttaattta gagttaacta cctgcttagg ccccagaaca   2040

ttacttatgc ccttcagtta ccaaaagatt tgtgcaaggt tttgtaccct ggtaaatgat   2100

gccaaagttt gttttctgtg gtgtttgtca aatgttctat gtataattaa ctgtctgtaa   2160

catgctgttt ccttcctctg cagatgtagc tgctttccta aatctgtctg tctttcttta   2220

ggttagctgt atgtctgtaa aagtatgttc aattaaatta ctccatcaga cacttgtctg   2280

tcttgcaatg tagaagcagc tttgtagcac cttgttttga ggtttgctgc atttgttgct   2340

gcactttgtg cattctgaac atgaatgtaa cattagatat taagtcattg ttataagggg   2400

ttgaatttaa atcctgtaag tcaaaattga aagggtgtta ttaagtgtgc ctttattttg   2460

catgaaaata aaaagaatta tacgtaaagc attcctgtaa tctggctcat tgaatatttt   2520

atacttaaaa aacttttttt ggcgtaaata tttgtgtaaa tactgggtta actttttaaa   2580

agcccattac agatt                                                    2595


<210>  7069
<211>  514
<212>  PRT
<213>  Homo sapiens

<400>  7069

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu His Val Leu Gly Thr Glu Asp 
    130                 135                 140


Ile Ser Ile Asn Pro His Asn Asn Ile Asn Glu Cys Val Leu Tyr Leu 
145                 150                 155                 160


Trp Val Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly 
                165                 170                 175


Asn His Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu 
            180                 185                 190


Cys Lys Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala 
        195                 200                 205


Phe Asp Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys 
    210                 215                 220


Val His Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg 
225                 230                 235                 240


Arg Leu Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp 
                245                 250                 255


Leu Leu Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln 
            260                 265                 270


Glu His Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn 
        275                 280                 285


Tyr Pro Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile 
    290                 295                 300


Ile Arg Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys 
305                 310                 315                 320


Ser Gln Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro 
                325                 330                 335


Asn Tyr Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu 
            340                 345                 350


Asn Asn Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr 
        355                 360                 365


Trp Leu Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val 
    370                 375                 380


Gly Glu Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser 
385                 390                 395                 400


Asp Asp Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala 
                405                 410                 415


Ala Ala Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys 
            420                 425                 430


Met Ala Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu 
        435                 440                 445


Thr Leu Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu 
    450                 455                 460


Ala Gly Gly Arg Gln Thr Leu Gln Ser Gly Asn Asp Val Met Gln Leu 
465                 470                 475                 480


Ala Val Pro Gln Met Asp Trp Gly Thr Pro His Ser Phe Ala Asn Asn 
                485                 490                 495


Ser His Asn Ala Cys Arg Glu Phe Leu Leu Phe Phe Ser Ser Cys Leu 
            500                 505                 510


Ser Ser 



<210>  7070
<211>  2498
<212>  DNA
<213>  Homo sapiens

<400>  7070
atgccggtct tagcccctct gtagggaaag agggtccgcc atgttccccg gcggcgccgc     60

cgcttggctc tggtagccgc cgcccccgcc cccaaccccg cccggcccag agcctagccg    120

agccccgggc ccagcatggc cgccccggag ccggcccggg ctgcaccgcc cccacccccg    180

cccccgccgc cccctcccgg ggctgaccgc gtcgtcaaag ctgtcccttt ccccccaaca    240

catcgcttga catctgaaga agtatttgat ttggatggga tacccagggt tgatgttctg    300

aagaaccact tggtgaaaga aggtcgagta gatgaagaaa ttgcgcttag aattatcaat    360

gagggtgctg ccatccttcg gagagagaaa accatgatag aagtagaagc tccaatcaca    420

gtgtgtggtg acatccatgg ccaatttttt gatctgatga aactttttga agtaggagga    480

tcacctgcta atacacgata cctttttctt ggcgattatg tggacagagg ttattttagt    540

atagagcatg ttctaggcac tgaagacata tcgattaatc ctcacaataa tattaatgag    600

tgtgtcttat atttatgggt tctgaagatt ctatacccaa gcacattatt tcttctgaga    660

ggcaaccatg aatgcagaca ccttactgaa tattttacct ttaagcagga atgtaaaatt    720

aagtattcgg aaagagtcta tgaagcttgt atggaagctt ttgatagttt gcctcttgct    780

gcacttttaa accaacagtt tctttgtgtt catggtggac tttcaccaga aatacacaca    840

ctggatgata ttaggagatt agatagattc aaagagccac ctgcatttgg accaatgtgt    900

gacttgttat ggtccgatcc ttctgaagat tttggaaatg aaaaatcaca ggaacatttt    960

agtcacaata cagttcgagg atgttcttat ttttataact atccagcagt gtgtgaattt   1020

ttgcaaaaca ataatttgtt atcgattatt agagctcatg aagctcaaga tgcaggctat   1080

agaatgtaca gaaaaagtca aactacaggg ttcccttcat taataacaat tttttcggca   1140

cctaattact tagatgtcta caataataaa gctgctgtat taaagtatga aaataatgtg   1200

atgaatattc gacagtttaa ctgttctcca catccttact ggttgcctaa ttttatggat   1260

gtcttcacgt ggtctttacc gtttgttgga gaaaaagtga cagaaatgtt ggtaaatgtt   1320

ctgagtattt gctctgatga tgaactaatg actgaaggtg aagaccagtt tgatggttca   1380

gctgcagccc ggaaagaaat cataagaaac aaaattcgag caattggcaa gatggcaaga   1440

gtcttctctg ttctcaggga ggagagtgaa agtgtgctga cactcaaggg cctgactccc   1500

acagggatgt tgcctagtgg agtgttagct ggaggacggc agaccctgca aagtggtaat   1560

gatgttatgc aacttgctgt gcctcagatg gactggggca cacctcactc ttttgctaac   1620

aattcacata atgcatgcag ggaattcctt ctgtttttta gttcctgtct cagcagctga   1680

cctagacagg gtactgtatt agctagtgtc tcattaatac ctgatcaggg cagaaaactg   1740

atagaatggg tattcctttc aattgaaaat aatggtcagt tcctcagctt ttcatgaaat   1800

gatatgggag cagctcatat cataatgtct gaaatattta tttattcatc tgtctaattc   1860

acccttttct tttaaaagcc ccagtttcag aatgtgaatc agggatattc ctgttactaa   1920

aatggaaatg taattccaag tttctttttt aattttttaa atttatgtca ttgtattgga   1980

ctatgcttat atttaaaact acttaattta gagttaacta cctgcttagg ccccagaaca   2040

ttacttatgc ccttcagtta ccaaaagatt tgtgcaaggt tttgtaccct ggtaaatgat   2100

gccaaagttt gttttctgtg gtgtttgtca aatgttctat gtataattaa ctgtctgtaa   2160

catgctgttt ccttcctctg cagatgtagc tgctttccta aatctgtctg tctttcttta   2220

ggttagctgt atgtctgtaa aagtatgttc aattaaatta ctccatcaga cacttgtctg   2280

tcttgcaatg tagaagcagc tttgtagcac cttgttttga ggtttgctgc atttgttgct   2340

gcactttgtg cattctgaac atgaatgtaa cattagatat taagtcattg ttataagggg   2400

ttgaatttaa atcctgtaag tcaaaattga aagggtgtta ttaagtgtgc ctttattttg   2460

catgaaaata aaaagaatta tacgtaaagc attcctgt                           2498


<210>  7071
<211>  514
<212>  PRT
<213>  Homo sapiens

<400>  7071

Met Ala Ala Pro Glu Pro Ala Arg Ala Ala Pro Pro Pro Pro Pro Pro 
1               5                   10                  15


Pro Pro Pro Pro Pro Gly Ala Asp Arg Val Val Lys Ala Val Pro Phe 
            20                  25                  30


Pro Pro Thr His Arg Leu Thr Ser Glu Glu Val Phe Asp Leu Asp Gly 
        35                  40                  45


Ile Pro Arg Val Asp Val Leu Lys Asn His Leu Val Lys Glu Gly Arg 
    50                  55                  60


Val Asp Glu Glu Ile Ala Leu Arg Ile Ile Asn Glu Gly Ala Ala Ile 
65                  70                  75                  80


Leu Arg Arg Glu Lys Thr Met Ile Glu Val Glu Ala Pro Ile Thr Val 
                85                  90                  95


Cys Gly Asp Ile His Gly Gln Phe Phe Asp Leu Met Lys Leu Phe Glu 
            100                 105                 110


Val Gly Gly Ser Pro Ala Asn Thr Arg Tyr Leu Phe Leu Gly Asp Tyr 
        115                 120                 125


Val Asp Arg Gly Tyr Phe Ser Ile Glu His Val Leu Gly Thr Glu Asp 
    130                 135                 140


Ile Ser Ile Asn Pro His Asn Asn Ile Asn Glu Cys Val Leu Tyr Leu 
145                 150                 155                 160


Trp Val Leu Lys Ile Leu Tyr Pro Ser Thr Leu Phe Leu Leu Arg Gly 
                165                 170                 175


Asn His Glu Cys Arg His Leu Thr Glu Tyr Phe Thr Phe Lys Gln Glu 
            180                 185                 190


Cys Lys Ile Lys Tyr Ser Glu Arg Val Tyr Glu Ala Cys Met Glu Ala 
        195                 200                 205


Phe Asp Ser Leu Pro Leu Ala Ala Leu Leu Asn Gln Gln Phe Leu Cys 
    210                 215                 220


Val His Gly Gly Leu Ser Pro Glu Ile His Thr Leu Asp Asp Ile Arg 
225                 230                 235                 240


Arg Leu Asp Arg Phe Lys Glu Pro Pro Ala Phe Gly Pro Met Cys Asp 
                245                 250                 255


Leu Leu Trp Ser Asp Pro Ser Glu Asp Phe Gly Asn Glu Lys Ser Gln 
            260                 265                 270


Glu His Phe Ser His Asn Thr Val Arg Gly Cys Ser Tyr Phe Tyr Asn 
        275                 280                 285


Tyr Pro Ala Val Cys Glu Phe Leu Gln Asn Asn Asn Leu Leu Ser Ile 
    290                 295                 300


Ile Arg Ala His Glu Ala Gln Asp Ala Gly Tyr Arg Met Tyr Arg Lys 
305                 310                 315                 320


Ser Gln Thr Thr Gly Phe Pro Ser Leu Ile Thr Ile Phe Ser Ala Pro 
                325                 330                 335


Asn Tyr Leu Asp Val Tyr Asn Asn Lys Ala Ala Val Leu Lys Tyr Glu 
            340                 345                 350


Asn Asn Val Met Asn Ile Arg Gln Phe Asn Cys Ser Pro His Pro Tyr 
        355                 360                 365


Trp Leu Pro Asn Phe Met Asp Val Phe Thr Trp Ser Leu Pro Phe Val 
    370                 375                 380


Gly Glu Lys Val Thr Glu Met Leu Val Asn Val Leu Ser Ile Cys Ser 
385                 390                 395                 400


Asp Asp Glu Leu Met Thr Glu Gly Glu Asp Gln Phe Asp Gly Ser Ala 
                405                 410                 415


Ala Ala Arg Lys Glu Ile Ile Arg Asn Lys Ile Arg Ala Ile Gly Lys 
            420                 425                 430


Met Ala Arg Val Phe Ser Val Leu Arg Glu Glu Ser Glu Ser Val Leu 
        435                 440                 445


Thr Leu Lys Gly Leu Thr Pro Thr Gly Met Leu Pro Ser Gly Val Leu 
    450                 455                 460


Ala Gly Gly Arg Gln Thr Leu Gln Ser Gly Asn Asp Val Met Gln Leu 
465                 470                 475                 480


Ala Val Pro Gln Met Asp Trp Gly Thr Pro His Ser Phe Ala Asn Asn 
                485                 490                 495


Ser His Asn Ala Cys Arg Glu Phe Leu Leu Phe Phe Ser Ser Cys Leu 
            500                 505                 510


Ser Ser 



<210>  7072
<211>  959
<212>  DNA
<213>  Homo sapiens

<400>  7072
aatctgctga cctgttgtgg gtaaacatcc ataaattctg ccctggctga gaaacattta     60

actttttcgt ctaggatgaa tgtgtgggtg tgtgtttgta agggaggggt aactcctttt    120

gaccaaagtg ttgatggttt tctaagtaaa tacttgctat ccacaagaat tttttttttc    180

gtttatgctg ctttttctcc ctttctgcac tataaaggct ggccttccaa ttcctgcccc    240

gacccttcac cgtgatccaa tcccacaagg ttcccctaat ttctgctccg ggtggcacct    300

gacggccaaa agtgaacccc tgcggttgtc gccagctaga cgcggatagg gcggacgact    360

gtcaccgggg agcaggcgtg ggccaaagcc gaggtgattt ctgactgctc actggcgggc    420

ctcgcgtggc tgaaggtctc cgagcccctc ggttcgcccc ggcaagccag aagtgcagct    480

gtcgcggggc aggaagctaa tcgcggcccc tgcgccgctt tgacaggccg agtgaagaga    540

aaacgggctc actgcagcta acagcctcac cccttgggct aggaagccac ggaagcaaaa    600

cctccgcccc ggcctgaaag caaccgggag accgcggaac cactgccacc gactcagccc    660

tgcccagcag gggcccgccc aggggccact ccccaaggga ggcagccagt cactcgcccg    720

cccttccggg cccactcccg aggggacggt ctcccgcccg ccctcacaca cagctagctc    780

ttcaggccag gcccccaggg tttcgtccac ctctcacctt tgacgacgcg aatgaagaat    840

gaggaggtgc tgcgatcgaa cgactgcgag gaaacacacc cgctctcatg gcattcccag    900

taaactgaga agacgtgatt aaacctcagg atctcctact aatagagaaa tgtataacg     959


<210>  7073
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  7073

Met Asn Val Trp Val Cys Val Cys Lys Gly Gly Val Thr Pro Phe Asp 
1               5                   10                  15


Gln Ser Val Asp Gly Phe Leu Ser Lys Tyr Leu Leu Ser Thr Arg Ile 
            20                  25                  30


Phe Phe Phe Val Tyr Ala Ala Phe Ser Pro Phe Leu His Tyr Lys Gly 
        35                  40                  45


Trp Pro Ser Asn Ser Cys Pro Asp Pro Ser Pro 
    50                  55


<210>  7074
<211>  1133
<212>  DNA
<213>  Homo sapiens

<400>  7074
cacacacagc tagctcttca ggccaggccc ccagggtttc gtccacctct cacctttgac     60

gacgcgaatg aagaatgagg aggtgctgcg atcgaacgac tgcgaggaaa cacacccgct    120

ctcatggcat tcccagtaaa ctgagaagac gtgattaaac ctcaggatct cctactaata    180

gagaaatgta taacgattta gctaccagat ctgaatactg aagggttggt aggggaccag    240

agaatagagg aagcattgta ggttctagag tggagaaggg accatccaaa atggagtttg    300

aaagagaatt ctggcctttg tgtttagagt ctggaattgt caagagtctg aaagcacaga    360

ataagactgc agctagagca atttaggcgc catagtttgt caaaacaggt aaggggaata    420

aaggggatga caccaagaga tgtgcaaaga atctgaagaa ttcacctgaa aaggatacaa    480

cctcctcctg gaaggcagag gagtaaatag ggaattggaa attaattcct tatttctgca    540

catgcacaga atctgggccc aggtgactta tggaaccttt atagagacca cggtgactga    600

cactcatggg aaagggggta gaggggcaag aactgactgt tcatcaaaaa ttattagatg    660

agtgtgtcca cgacaccagg agatatgttg aatcatggac agggaccagc atatccacta    720

agctctatat atcttgatgg tgcaggatcc aagtgggatg gaacaaccaa ttcctgccca    780

tcctcctgct caataataca tgtgctcaga atctgttcat aatgcatggt ggtaagtaag    840

tagtagtccg aaggtccaag gagtaccttt ctacctcttc tttgtgtcaa tttctatcct    900

gagaccccag gaaaagagga agggaaagac ccaacaatgg attttttcca aaaagggaac    960

ccacaagcta ttttttagag ggaagagtct cgggagtgag gcacaggtga aaatggatct   1020

ttctggcatg gaagggccat aacaccacag gggaagggaa agggagaggc ccccacggaa   1080

ggagaggaag gaagggacag gaggcacgtc acaaacttat aagatagagg gaa          1133


<210>  7075
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  7075

Met Ser Val Ser Thr Thr Pro Gly Asp Met Leu Asn His Gly Gln Gly 
1               5                   10                  15


Pro Ala Tyr Pro Leu Ser Ser Ile Tyr Leu Asp Gly Ala Gly Ser Lys 
            20                  25                  30


Trp Asp Gly Thr Thr Asn Ser Cys Pro Ser Ser Cys Ser Ile Ile His 
        35                  40                  45


Val Leu Arg Ile Cys Ser 
    50


<210>  7076
<211>  1780
<212>  DNA
<213>  Homo sapiens

<400>  7076
gcatgcagaa tgaagaatga ggaggtgctg cgatcgaacg actgcgagga aacacacccg     60

ctctcatggc attcccagta aactgagaag acgtgattaa acctcaggat ctcctactaa    120

tagagaaatg tataacgatt tagctaccag atctgaatac tgaagggttg gtaggggacc    180

agagaataga ggaagcattg taggttctag agtggagaag ggaccatcca aaatggagtt    240

tgaaagagaa ttctggcctt tgtgtttaga gtctggaatt gtcaagagtc tgaaagcaca    300

gaataagact gcagctagag caatttaggc gccatagttt gtcaaaacag agacgggatc    360

tcactgtgtt gcccaggctg gtctcgaact gctggactca agtcatcctc ccatcttggc    420

ctcccaaagt gctggaatta cagtggacaa ccttcaatgc actggtactt tgtaccctga    480

cctctactgt gatgaacact caacttgggc aaggaagtga aattctccaa aggcccagca    540

ccttagcacc tgaggctgct acctgagaag tacgcactgt tctggcttca tggagaccat    600

gctccatttc tgctgttgaa gtctttgaga gaccaggatc atgggctgag tgcaacctcc    660

tccccatgcc atctgcagag cctgaagagg aaaacacaaa tacaagttga ggccatctct    720

tcccctaggg cctaacctct aagcctagca gcacaaactc aggagctgtt gtttcattta    780

ataataaata tgcatccttg aattcaacgg aggaacatgc tcctggaatt tagaagcaag    840

aggggctggg cgcggtggct cacacctgta atcccagcac tttgggaggc caacacgggc    900

agatcacgag gtcaggagat cgagaccacc ctggctaaca tggtaaaacc ctgtctctac    960

taaaaataca aaaaattagc cgggcgtggt ggcaggcacc tgtaatccca gctactcggg   1020

aggctgaggc aggagaatgg cgtgaacccg ggaggcgtag cttgcagtga gcggagatca   1080

cgccactgca ctccagcccg ggtgacagag cgagactccg tctcaaaaaa aaaaagaaac   1140

aagaatttta gaatatagat agtttactga gtgtccccat cttgcttcat ttcatttttg   1200

taaacataat cagcttctgt cagacttagg ctcaagactt atagacagag gaaagtatct   1260

aacacagtga gttttgtttt ctaacacagt gattttctaa agtatctgtg gtgacaaagg   1320

aaattatctc cagtctagtt cagaatagaa atgatcataa taatcatcta tcaaacctcc   1380

tcattttata taacaggaaa atgagttcca gggtctgaga gtttagtagt ttaaccagga   1440

ttaaaattaa atcctcttga ttttcagtac agtactctta ccatctcacc tggtgacctc   1500

ttttactctg agagcaggag ctcctcagga atgttttaca tatgtaatgc tcttttcccc   1560

ttagcttctc tcaaatcatt taaatttcta aacaaccact aaatgcttac ctcttttcaa   1620

aatctttcta gattgttcag ttgctctaaa ctggattggt gactcccaag gggctatccc   1680

caatccaact aattaagttt tccattccaa aactgtatat gcccctgacc tacatttgat   1740

acatatgtcc atggccaatt catgtcttga tttgatgatt                         1780


<210>  7077
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  7077

Met Leu Leu Glu Phe Arg Ser Lys Arg Gly Trp Ala Arg Trp Leu Thr 
1               5                   10                  15


Pro Val Ile Pro Ala Leu Trp Glu Ala Asn Thr Gly Arg Ser Arg Gly 
            20                  25                  30


Gln Glu Ile Glu Thr Thr Leu Ala Asn Met Val Lys Pro Cys Leu Tyr 
        35                  40                  45


<210>  7078
<211>  2105
<212>  DNA
<213>  Homo sapiens

<400>  7078
agatctgaat actgaagggt tggtagggga ccagagaata gaggaagcat tgtaggttct     60

agagtggaga agggaccatc caaaatggag tttgaaagag aattctggcc tttgtgttta    120

gagtctggaa ttgtcaagag tctgaaagca cagaataaga ctgcagctag agcaatttag    180

gcgccatagt ttgtcaaaac agagacggga tctcactgtg ttgcccaggc tggtctcgaa    240

ctgctggact caagtcatcc tcccatcttg gcctcccaaa gtgctggaat tacagtggac    300

aaccttcaat gcactggtac tttgtaccct gacctctact gtgatgaaca ctcaacttgg    360

gcaaggaagt gaaattctcc aaagcaagga ggagggtgct ctgaatagat ggaccctgat    420

tctacttaca aaactgtggg aagaaaccgg agcttcctcc ctctctgaga caacggtgcc    480

actgagactg cgtgagatgc gacgtaaatt ctctgcactg tactgctcat cctccccaca    540

ctccctgctg aggcctcggc aaggtgtagc cttcaaacac acagacacat acaggcagac    600

acataatacc agacttatgg ttttcccaca gacagtatcc tcagggtatg ggaaagagta    660

ggggaagact cagtagtaat agacacctga attagatgta ttggtaagat agtggccatg    720

taacaatctc ctctaattca aaagaagccc aatcatagac cttattttct tctgatagcc    780

ccatatcacc atgcctctgc cttatcatca tccctgtcac atctctccat aattccttcc    840

ccaacacacc accccaggcc cagcacctta gcacctgagg ctgctacctg agaagtacgc    900

actgttctgg cttcatggag accatgctcc atttctgctg ttgaagtctt tgagagacca    960

ggatcatggg ctgagtgcaa cctcctcccc atgccatctg cagagcctga agaggaaaac   1020

acaaatacaa gttgaggcca tctcttcccc tagggcctaa cctctaagcc tagcagcaca   1080

aactcaggag ctgttgtttc atttaataat aaatatgcat ccttgaattc aacggaggaa   1140

catgctcctg gaatttagaa gcaagagggg ctgggcgcgg tggctcacac ctgtaatccc   1200

agcactttgg gaggccaaca cgggcagatc acgaggtcag gagatcgaga ccaccctggc   1260

taacatggta aaaccctgtc tctactaaaa atacaaaaaa ttagccgggc gtggtggcag   1320

gcacctgtaa tcccagctac tcgggaggct gaggcaggag aatggcgtga acccgggagg   1380

cgtagcttgc agtgagcgga gatcacgcca ctgcactcca gcccgggtga cagagcgaga   1440

ctccgtctca aaaaaaaaaa gaaacaagaa ttttagaata tagatagttt actgagtgtc   1500

cccatcttgc ttcatttcat ttttgtaaac ataatcagct tctgtcagac ttaggctcaa   1560

gacttataga cagaggaaag tatctaacac agtgagtttt gttttctaac acagtgattt   1620

tctaaagtat ctgtggtgac aaaggaaatt atctccagtc tagttcagaa tagaaatgat   1680

cataataatc atctatcaaa cctcctcatt ttatataaca ggaaaatgag ttccagggtc   1740

tgagagttta gtagtttaac caggattaaa attaaatcct cttgattttc agtacagtac   1800

tcttaccatc tcacctggtg acctctttta ctctgagagc aggagctcct caggaatgtt   1860

ttacatatgt aatgctcttt tccccttagc ttctctcaaa tcatttaaat ttctaaacaa   1920

ccactaaatg cttacctctt ttcaaaatct ttctagattg ttcagttgct ctaaactgga   1980

ttggtgactc ccaaggggct atccccaatc caactaatta agttttccat tccaaaactg   2040

tatatgcccc tgacctacat ttgatacata tgtccatggc caattcatgt cttgatttga   2100

tgatt                                                               2105


<210>  7079
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  7079

Met Asn Thr Gln Leu Gly Gln Gly Ser Glu Ile Leu Gln Ser Lys Glu 
1               5                   10                  15


Glu Gly Ala Leu Asn Arg Trp Thr Leu Ile Leu Leu Thr Lys Leu Trp 
            20                  25                  30


Glu Glu Thr Gly Ala Ser Ser Leu Ser Glu Thr Thr Val Pro Leu Arg 
        35                  40                  45


Leu Arg Glu Met Arg Arg Lys Phe Ser Ala Leu Tyr Cys Ser Ser Ser 
    50                  55                  60


Pro His Ser Leu Leu Arg Pro Arg Gln Gly Val Ala Phe Lys His Thr 
65                  70                  75                  80


Asp Thr Tyr Arg Gln Thr His Asn Thr Arg Leu Met Val Phe Pro Gln 
                85                  90                  95


Thr Val Ser Ser Gly Tyr Gly Lys Glu 
            100                 105


<210>  7080
<211>  2361
<212>  DNA
<213>  Homo sapiens

<400>  7080
tctcaaagac ttcaacagca gaaatggagc atggtctcca tgaagccaga acagtgcgta     60

cttctcaggt agcagcctca ggtgctaagg tgctgggcct ggggtggtgt gttggggaag    120

gaattatgga gagatgtgac agggatgatg ataaggcaga ggcatggtga tatggggcta    180

tcagaagaaa ataaggtcta tgattgggct tcttttgaat tagaggagat tgttacatgg    240

ccactatctt accaatacat ctaattcagg tgtctattac tactgagtct tcccctactc    300

tttcccatac cctgaggata ctgtctgtgg gaaaaccata agtctggtat tatgtgtctg    360

cctgtatgtg tctgtgtgtt tgaaggctac accttgccga ggcctcagca gggagtgtgg    420

ggaggatgag cagtacagtg cagagaattt acgtcgcatc tcacgcagtc tcagtggcac    480

cgttgtctca gagagggagg aagctccggt ttcttcccac agttttgatt catcaaacgt    540

gaggaagcct ttggaaaccg ggcaccgttg ttccagctcc tcttccctcc ctgtcatcca    600

tgacccttct gtgtttctcc tcggtcccca actctacctt ccccaaccac agttcctgtc    660

cccagatgtc ctgatgccca ccatggcagg ggagcccaat agactcccag gaacttcaag    720

gagtgtccag cagtttctgg ctatgtgtga caggggtgaa acttcccaag gggccaagta    780

cacaggaagg actttgaact accagagcct cccccatcgc tccagaacag acaactcctg    840

ggcaccctgg tcagagacca accagcatat tgggaccaga ttcctgacta ctccagggtg    900

caatcctcaa ctaacctaca ctgccacact accagaaaga agcaagggcc ttcaggttcc    960

tcacactcag tcctggagtg atcttttcca ttcaccctcc caccctccca ttgttcatcc   1020

tgtgtaccca ccatctagca gtcttcatgt acccctgagg tcagcttgga attcagatcc   1080

tgttccaggg tcccgaaccc ctggtcctcg aagagtagat atgcccccag atgatgactg   1140

gaggcaaagc agttatgcct cccactctgg acacaggaga acagtgggag aggggtttct   1200

gtttgttcta tcagatgctc ccagaagaga gcagatcagg gctagagtcc tgcagcacag   1260

tcaatggtaa aggttattcc tttcctttcc tggagctaca cctttctttg taaaactgta   1320

ctgtgggccg ggcgcggtgg ctcacacctg taatcccagc actttgggag gctgaggcgg   1380

gtggatcacg aggtcaggag attgagacca tcctggccaa catggtgaaa ccccgtctct   1440

accaaaatac aaaaaattag ccaggcgtga cggtgcgtgc ctgtagtccc aactactcgg   1500

aaggctgagg caggagaatt gcttgaaccc gggaggcaga ggttgcagtg agccgagatc   1560

gcaccactgc actccagctt ggcaatagag tgagactcca tctcaaaaaa caaaacaaaa   1620

caacaacaaa ataaactact gtggcagcgt tggtaccctg catcactgcc atggttgtgc   1680

tattctcatc tcaacataga attggtgggt tctcctaagg gtgtcaggaa cctctaaaaa   1740

gatgtgattc tttgggaggg gatatttgaa attccaactt ccattccccc tagcaaaagg   1800

aagcagctgc tgtttaaggg ttttatctga gccactttaa agatgaatcc atggtattac   1860

tctggatact agccattcct taggatttta aggtcacatt ttattcctgg atgctttatg   1920

tccccacctc cacctgagcc ctcatcctct gttccctact atactcccaa cttctactct   1980

ttgttttatc cacctatccc tattacctga ccctttgtct tccctgtctc ccatccttgg   2040

ggggacatgt agccctgtgg tcatggttct gatgacatca tcagggcagc ccccctgccc   2100

aggtattatg gcctgtcagc attccctgtg ccctccaaac cttaggccta gaatgcggag   2160

ctgccaacat aacattcacc cttttgaaca gatggagtca ggcacactaa cacagccttc   2220

tgtcctcaat aacacagcca ttattgccac ttgctcagtc gtcaatgtaa accctcagag   2280

tcagctgaac tattttaggc caaacatact gtttttgtaa agtatttttc attaataaat   2340

ctataagaca gttctattta a                                             2361


<210>  7081
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  7081

Met Pro Thr Met Ala Gly Glu Pro Asn Arg Leu Pro Gly Thr Ser Arg 
1               5                   10                  15


Ser Val Gln Gln Phe Leu Ala Met Cys Asp Arg Gly Glu Thr Ser Gln 
            20                  25                  30


Gly Ala Lys Tyr Thr Gly Arg Thr Leu Asn Tyr Gln Ser Leu Pro His 
        35                  40                  45


Arg Ser Arg Thr Asp Asn Ser Trp Ala Pro Trp Ser Glu Thr Asn Gln 
    50                  55                  60


His Ile Gly Thr Arg Phe Leu Thr Thr Pro Gly Cys Asn Pro Gln Leu 
65                  70                  75                  80


Thr Tyr Thr Ala Thr Leu Pro Glu Arg Ser Lys Gly Leu Gln Val Pro 
                85                  90                  95


His Thr Gln Ser Trp Ser Asp Leu Phe His Ser Pro Ser His Pro Pro 
            100                 105                 110


Ile Val His Pro Val Tyr Pro Pro Ser Ser Ser Leu His Val Pro Leu 
        115                 120                 125


Arg Ser Ala Trp Asn Ser Asp Pro Val Pro Gly Ser Arg Thr Pro Gly 
    130                 135                 140


Pro Arg Arg Val Asp Met Pro Pro Asp Asp Asp Trp Arg Gln Ser Ser 
145                 150                 155                 160


Tyr Ala Ser His Ser Gly His Arg Arg Thr Val Gly Glu Gly Phe Leu 
                165                 170                 175


Phe Val Leu Ser Asp Ala Pro Arg Arg Glu Gln Ile Arg Ala Arg Val 
            180                 185                 190


Leu Gln His Ser Gln Trp 
        195


<210>  7082
<211>  4069
<212>  DNA
<213>  Homo sapiens

<400>  7082
ttcaggacac ctgactgata gtgaatgtaa tcagaaacac acatccaaga aagggtcact     60

gatagagcgc aagaggagct ctggtcgggt taggaggaaa ggcgatgagc cccaggcctc    120

gggataccac agtgaaggag aaacactgaa agagaagcag gctcctagaa atgcctccaa    180

accatccagc agcaccaaca ggctgagaga ttttaaagag acagtcagca atatgatcca    240

taacagacca tccctggctt ctcagaccaa tgtaggctct cactgcaggg gcagaggagg    300

agaccagcct gacaaaaaac ctcctaggac cctgccttta cactctcgtg actgggaaat    360

agagagtacc agcagtgagt caaaatccag ttcttccagc aagtatcgtc ccacatggag    420

acccaaacga gaatctctga atattgacag tatctttagt aaggacaaaa ggaagcactg    480

tggctatacc cagcttagcc ccttttctga ggattcagct aaagaattta taccagatga    540

accaagcaag ccaccttctt acgacattaa atttggtgga ccaagccccc agtacaagcg    600

ctggggccca gcacggccag gctctcacct tttagagcag cacccccgac taatccagcg    660

aatggaatct ggctatgaaa gcagtgagag gaacagcagc agccctgtca gcctggatgc    720

agccctgcct gagagctcaa atgtctacag ggatccaagt gctaagagat cagctgggtt    780

ggttccttcc tggcgtcata tcccaaagtc gcacagcagt agcatcctgg aggtagactc    840

cacagcatcc atgggtggct ggacaaagag tcagcctttc tctggtgagg agatatcttc    900

taaaagtgaa ctggatgaat tgcaggaaga ggtggccagg agggcgcagg aacaggaact    960

tcgaagaaaa cgggagaagg agttagaggc agcgaaaggg tttaaccctc atcctagccg   1020

cttcatggac ttggatgaac tgcagaatca ggtgaacagc ctatcccgct ccaagtattg   1080

ttaagccaag aggcccaact ggaatccggc atggatacag agtttggggc cagttctttc   1140

ttccattcac ctgcttcctg ccatgagtca cactcatcac tatctccaga gtcatctgcc   1200

ccacagcaca gctcccccag tagatctgcc ttgaagcttc tgacttcggt tgaagtagac   1260

aacattgaac cctctgcatt ccacaggcaa ggtttaccta aagcaccagg gtggactgag   1320

aagaattctc atcatagttg ggagccattg gatgccccag agggtaagct gcaaggctct   1380

aggtgtgaca acagcagttg cagcaagctc cctccacaag aaggaagagg cattgctcaa   1440

gaacagctgt tccaagaaaa gaaggatcct gctaacccct ccccggtgat gcctggaata   1500

gccacctctg agaggggtga tgaacacagc ctaggctgta gtccttcaaa ttcatcagct   1560

cagcccagcc ttcccctgta tagaacctgc caccccataa tgcctgttgc ttcttcattt   1620

gtgcttcact gtcctgatcc tgtgcagaaa actaaccaat gcctccaagg ccaaagcctc   1680

aaaacttcat tgactttaaa agtggacaga ggcagtgagg agacctatag gccagagttt   1740

cccagcacaa aggggcttgt ccgttctctg gctgagcagt tccagaggat gcagggtgtc   1800

tccatgaggg atagtacagg tttcaaggat agaagtttgt caggtagtct aaggaagaac   1860

tcttcccctt ctgattctaa gcctcctttc tcacagggtc aagagaaagg ccactggcca   1920

tgggcaaagc aacaatcctc tctggagggt ggggatagac cactttcctg ggaagagtcc   1980

actgaacatt cttctcttgc cttaaactct gggctgccta atggtgaaac ttctagcgga   2040

ggacagccca ggttggcaga gccagacata taccaagaga agctgtccca agtgagagat   2100

gttaggtcta aggatctggg cagcagtact gacttgggga cttccttgcc tttggattcc   2160

tgggtgaata tcacaaggtt ctgtgattct cagcttaagc atggggcacc taggccagga   2220

atgaagtcct cccctcatga ttcccatacg tgtgtaacct atccagagag aaatcacatc   2280

cttttgcatc cacattggaa ccaagacaca gagcaggaga cctcagaatt ggagtctctg   2340

tatcaggcca gtcttcaggc ttctcaagct ggctgttctg gatgggggca gcaggatacc   2400

gcctggcacc cacttagcca aacaggctct gcagatggca tggggaggag gttgcactca   2460

gcccatgatc ctggtctctc aaagacttca acagcagaaa tggagcatgg tctccatgaa   2520

gccagaacag tgcgtacttc tcaggattca tcaaacgtga ggaagccttt ggaaaccggg   2580

caccgttgtt ccagctcctc ttccctccct gtcatccatg acccttctgt gtttctcctc   2640

ggtccccaac tctaccttcc ccaaccacag ttcctgtccc cagatgtcct gatgcccacc   2700

atggcagggg agcccaatag actcccagga acttcaagga gtgtccagca gtttctggct   2760

atgtgtgaca ggggtgaaac ttcccaaggg gccaagtaca caggaaggac tttgaactac   2820

cagagcctcc cccatcgctc cagaacagac aactcctggg caccctggtc agagaccaac   2880

cagcatattg ggaccagatt cctgactact ccagggtgca atcctcaact aacctacact   2940

gccacactac cagaaagaag caagggcctt caggttcctc acactcagtc ctggagtgat   3000

cttttccatt caccctccca ccctcccatt gttcatcctg tgtacccacc atctagcagt   3060

cttcatgtac ccctgaggtc agcttggaat tcagatcctg ttccagggtc ccgaacccct   3120

ggtcctcgaa gagtagatat gcccccagat gatgactgga ggcaaagcag ttatgcctcc   3180

cactctggac acaggagaac agtgggagag gggtttctgt ttgttctatc agatgctccc   3240

agaagagagc agatcagggc tagagtcctg cagcacagtc aatggtaaag gttattcctt   3300

tcctttcctg gagctacacc tttctttgta aaactgtact gtgctactgt ggcagcgttg   3360

gtaccctgca tcactgccat ggttgtgcta ttctcatctc aacatagaat tggtgggttc   3420

tcctaagggt gtcaggaacc tctaaaaaga tgtgattctt tgggagggga tatttgaaat   3480

tccaacttcc attcccccta gcaaaaggaa gcagctgctg tttaagggtt ttatctgagc   3540

cactttaaag atgaatccat ggtattactc tggatactag ccattcctta ggattttaag   3600

gtcacatttt attcctggat gctttatgtc cccacctcca cctgagccct catcctctgt   3660

tccctactat actcccaact tctactcttt gttttatcca cctatcccta ttacctgacc   3720

ctttgtcttc cctgtctccc atccttgggg ggacatgtag ccctgtggtc atggttctga   3780

tgacatcatc agggcagccc ccctgcccag gtattatggc ctgtcagcat tccctgtgcc   3840

ctccaaacct taggcctaga atgcggagct gccaacataa cattcaccct tttgaacaga   3900

tggagtcagg cacactaaca cagccttctg tcctcaataa cacagccatt attgccactt   3960

gctcagtcgt caatgtaaac cctcagagtc agctgaacta ttttaggcca aacatactgt   4020

ttttgtaaag tatttttcat taataaatct ataagacagt tctatttaa               4069


<210>  7083
<211>  725
<212>  PRT
<213>  Homo sapiens

<400>  7083

Met Asp Thr Glu Phe Gly Ala Ser Ser Phe Phe His Ser Pro Ala Ser 
1               5                   10                  15


Cys His Glu Ser His Ser Ser Leu Ser Pro Glu Ser Ser Ala Pro Gln 
            20                  25                  30


His Ser Ser Pro Ser Arg Ser Ala Leu Lys Leu Leu Thr Ser Val Glu 
        35                  40                  45


Val Asp Asn Ile Glu Pro Ser Ala Phe His Arg Gln Gly Leu Pro Lys 
    50                  55                  60


Ala Pro Gly Trp Thr Glu Lys Asn Ser His His Ser Trp Glu Pro Leu 
65                  70                  75                  80


Asp Ala Pro Glu Gly Lys Leu Gln Gly Ser Arg Cys Asp Asn Ser Ser 
                85                  90                  95


Cys Ser Lys Leu Pro Pro Gln Glu Gly Arg Gly Ile Ala Gln Glu Gln 
            100                 105                 110


Leu Phe Gln Glu Lys Lys Asp Pro Ala Asn Pro Ser Pro Val Met Pro 
        115                 120                 125


Gly Ile Ala Thr Ser Glu Arg Gly Asp Glu His Ser Leu Gly Cys Ser 
    130                 135                 140


Pro Ser Asn Ser Ser Ala Gln Pro Ser Leu Pro Leu Tyr Arg Thr Cys 
145                 150                 155                 160


His Pro Ile Met Pro Val Ala Ser Ser Phe Val Leu His Cys Pro Asp 
                165                 170                 175


Pro Val Gln Lys Thr Asn Gln Cys Leu Gln Gly Gln Ser Leu Lys Thr 
            180                 185                 190


Ser Leu Thr Leu Lys Val Asp Arg Gly Ser Glu Glu Thr Tyr Arg Pro 
        195                 200                 205


Glu Phe Pro Ser Thr Lys Gly Leu Val Arg Ser Leu Ala Glu Gln Phe 
    210                 215                 220


Gln Arg Met Gln Gly Val Ser Met Arg Asp Ser Thr Gly Phe Lys Asp 
225                 230                 235                 240


Arg Ser Leu Ser Gly Ser Leu Arg Lys Asn Ser Ser Pro Ser Asp Ser 
                245                 250                 255


Lys Pro Pro Phe Ser Gln Gly Gln Glu Lys Gly His Trp Pro Trp Ala 
            260                 265                 270


Lys Gln Gln Ser Ser Leu Glu Gly Gly Asp Arg Pro Leu Ser Trp Glu 
        275                 280                 285


Glu Ser Thr Glu His Ser Ser Leu Ala Leu Asn Ser Gly Leu Pro Asn 
    290                 295                 300


Gly Glu Thr Ser Ser Gly Gly Gln Pro Arg Leu Ala Glu Pro Asp Ile 
305                 310                 315                 320


Tyr Gln Glu Lys Leu Ser Gln Val Arg Asp Val Arg Ser Lys Asp Leu 
                325                 330                 335


Gly Ser Ser Thr Asp Leu Gly Thr Ser Leu Pro Leu Asp Ser Trp Val 
            340                 345                 350


Asn Ile Thr Arg Phe Cys Asp Ser Gln Leu Lys His Gly Ala Pro Arg 
        355                 360                 365


Pro Gly Met Lys Ser Ser Pro His Asp Ser His Thr Cys Val Thr Tyr 
    370                 375                 380


Pro Glu Arg Asn His Ile Leu Leu His Pro His Trp Asn Gln Asp Thr 
385                 390                 395                 400


Glu Gln Glu Thr Ser Glu Leu Glu Ser Leu Tyr Gln Ala Ser Leu Gln 
                405                 410                 415


Ala Ser Gln Ala Gly Cys Ser Gly Trp Gly Gln Gln Asp Thr Ala Trp 
            420                 425                 430


His Pro Leu Ser Gln Thr Gly Ser Ala Asp Gly Met Gly Arg Arg Leu 
        435                 440                 445


His Ser Ala His Asp Pro Gly Leu Ser Lys Thr Ser Thr Ala Glu Met 
    450                 455                 460


Glu His Gly Leu His Glu Ala Arg Thr Val Arg Thr Ser Gln Asp Ser 
465                 470                 475                 480


Ser Asn Val Arg Lys Pro Leu Glu Thr Gly His Arg Cys Ser Ser Ser 
                485                 490                 495


Ser Ser Leu Pro Val Ile His Asp Pro Ser Val Phe Leu Leu Gly Pro 
            500                 505                 510


Gln Leu Tyr Leu Pro Gln Pro Gln Phe Leu Ser Pro Asp Val Leu Met 
        515                 520                 525


Pro Thr Met Ala Gly Glu Pro Asn Arg Leu Pro Gly Thr Ser Arg Ser 
    530                 535                 540


Val Gln Gln Phe Leu Ala Met Cys Asp Arg Gly Glu Thr Ser Gln Gly 
545                 550                 555                 560


Ala Lys Tyr Thr Gly Arg Thr Leu Asn Tyr Gln Ser Leu Pro His Arg 
                565                 570                 575


Ser Arg Thr Asp Asn Ser Trp Ala Pro Trp Ser Glu Thr Asn Gln His 
            580                 585                 590


Ile Gly Thr Arg Phe Leu Thr Thr Pro Gly Cys Asn Pro Gln Leu Thr 
        595                 600                 605


Tyr Thr Ala Thr Leu Pro Glu Arg Ser Lys Gly Leu Gln Val Pro His 
    610                 615                 620


Thr Gln Ser Trp Ser Asp Leu Phe His Ser Pro Ser His Pro Pro Ile 
625                 630                 635                 640


Val His Pro Val Tyr Pro Pro Ser Ser Ser Leu His Val Pro Leu Arg 
                645                 650                 655


Ser Ala Trp Asn Ser Asp Pro Val Pro Gly Ser Arg Thr Pro Gly Pro 
            660                 665                 670


Arg Arg Val Asp Met Pro Pro Asp Asp Asp Trp Arg Gln Ser Ser Tyr 
        675                 680                 685


Ala Ser His Ser Gly His Arg Arg Thr Val Gly Glu Gly Phe Leu Phe 
    690                 695                 700


Val Leu Ser Asp Ala Pro Arg Arg Glu Gln Ile Arg Ala Arg Val Leu 
705                 710                 715                 720


Gln His Ser Gln Trp 
                725


<210>  7084
<211>  5655
<212>  DNA
<213>  Homo sapiens

<400>  7084
tagtgtgctg ctctaacaga ggggctttgt gctacagctt cttccagagc tccacagatg     60

catgctgggc gggctcagtc agctttaccc ctaatacact tgcttcttcc taacaatagc    120

agagcaagac tgacaacaat aattaaaata agagaataaa gaagatgtag tcagaggcca    180

ttctgaatgc attcagattc tcagtgtgta tgaggaaggc tgcctgtaat taagagggaa    240

tctttaacca gtttcagtgt agtagtgaaa aagtgcttcc atctgacact ctccgcagtg    300

ctctggcaaa gactttccag gatgaacaac gtttccagct gggaattatg gatgatgctg    360

cagagtgctt tgaaaacctc ctgatgagaa ttcacttcca cattgctgat gaaaccaaag    420

aggatatatg tactgcccaa cactgcattt cccatcagaa atttgcaatg acattgtttg    480

agcagtgtgt atgtactagc tgtggtgcca cttctgatcc gctgcctttc atccagatgg    540

tacattatat ctccaccact tccctttgca atcaggctat ttgtatgctg gaaagacgag    600

agaaaccttc accaagcatg tttggtgagc tgctgcagaa tgccagcacc atgggggatc    660

tgcggaactg tccaagcaac tgtggagaga ggatcaggat tcgccgtgtg ttgatgaatg    720

ctccacagat tatcacgatt gggctggtat gggactcaga ccactcagac ttagcagaag    780

atgttatcca cagcctggga acctgcctta agctgggtga tctgtttttc agagtgacgg    840

atgaccgggc caagcaatct gaactgtact tagttggaat gatctgttac tatggcaaac    900

attattctac attctttttt caaacaaaga ttcgcaaatg gatgtatttt gatgatgctc    960

atgtcaagga gattgggccc aaatggaagg atgtggtgac caaatgcatc aaggggcatt   1020

atcagcccct gctgctgctt tatgcagatc cccagggtac cccagtttcc acccaggacc   1080

tgcctcccca agctgagttc cagtcataca gcaggacatg ctacgacagt gaagattcag   1140

gacacctgac tgatagtgaa tgtaatcaga aacacacatc caagaaaggg tcactgatag   1200

agcgcaagag gagctctggt cgggttagga ggaaaggcga tgagccccag gcctcgggat   1260

accacagtga aggagaaaca ctgaaagaga agcaggctcc tagaaatgcc tccaaaccat   1320

ccagcagcac caacaggctg agagatttta aagagacagt cagcaatatg atccataaca   1380

gaccatccct ggcttctcag accaatgtag gctctcactg caggggcaga ggaggagacc   1440

agcctgacaa aaaacctcct aggaccctgc ctttacactc tcgtgactgg gaaatagaga   1500

gtaccagcag tgagtcaaaa tccagttctt ccagcaagta tcgtcccaca tggagaccca   1560

aacgagaatc tctgaatatt gacagtatct ttagtaagga caaaaggaag cactgtggct   1620

atacccagct tagccccttt tctgaggatt cagctaaaga atttatacca gatgaaccaa   1680

gcaagccacc ttcttacgac attaaatttg gtggaccaag cccccagtac aagcgctggg   1740

gcccagcacg gccaggctct caccttttag agcagcaccc ccgactaatc cagcgaatgg   1800

aatctggcta tgaaagcagt gagaggaaca gcagcagccc tgtcagcctg gatgcagccc   1860

tgcctgagag ctcaaatgtc tacagggatc caagtgctaa gagatcagct gggttggttc   1920

cttcctggcg tcatatccca aagtcgcaca gcagtagcat cctggaggta gactccacag   1980

catccatggg tggctggaca aagagtcagc ctttctctgg tgaggagata tcttctaaaa   2040

gtgaactgga tgaattgcag gaagaggtgg ccaggagggc gcaggaacag gaacttcgaa   2100

gaaaacggga gaaggagtta gaggcagcga aagggtttaa ccctcatcct agccgcttca   2160

tggacttgga tgaactgcag aatcaggtga acagcctatc ccgctccaag tattgttaag   2220

ccaagaggcc caactggaat ccggcatgga tacagagttt ggggccagtt ctttcttcca   2280

ttcacctgct tcctgccatg agtcacactc atcactatct ccagagtcat ctgccccaca   2340

gcacagctcc cccagtagat ctgccttgaa gcttctgact tcggttgaag tagacaacat   2400

tgaaccctct gcattccaca ggcaaggttt acctaaagca ccagggtgga ctgagaagaa   2460

ttctcatcat agttgggagc cattggatgc cccagagggt aagctgcaag gctctaggtg   2520

tgacaacagc agttgcagca agctccctcc acaagaagga agaggcattg ctcaagaaca   2580

gctgttccaa gaaaagaagg atcctgctaa cccctccccg gtgatgcctg gaatagccac   2640

ctctgagagg ggtgatgaac acagcctagg ctgtagtcct tcaaattcat cagctcagcc   2700

cagccttccc ctgtatagaa cctgccaccc cataatgcct gttgcttctt catttgtgct   2760

tcactgtcct gatcctgtgc agaaaactaa ccaatgcctc caaggccaaa gcctcaaaac   2820

ttcattgact ttaaaagtgg acagaggcag tgaggagacc tataggccag agtttcccag   2880

cacaaagggg cttgtccgtt ctctggctga gcagttccag aggatgcagg gtgtctccat   2940

gagggatagt acaggtttca aggatagaag tttgtcaggt agtctaagga agaactcttc   3000

cccttctgat tctaagcctc ctttctcaca gggtcaagag aaaggccact ggccatgggc   3060

aaagcaacaa tcctctctgg agggtgggga tagaccactt tcctgggaag agtccactga   3120

acattcttct cttgccttaa actctgggct gcctaatggt gaaacttcta gcggaggaca   3180

gcccaggttg gcagagccag acatatacca agagaagctg tcccaagtga gagatgttag   3240

gtctaaggat ctgggcagca gtactgactt ggggacttcc ttgcctttgg attcctgggt   3300

gaatatcaca aggttctgtg attctcagct taagcatggg gcacctaggc caggaatgaa   3360

gtcctcccct catgattccc atacgtgtgt aacctatcca gagagaaatc acatcctttt   3420

gcatccacat tggaaccaag acacagagca ggagacctca gaattggagt ctctgtatca   3480

ggccagtctt caggcttctc aagctggctg ttctggatgg gggcagcagg ataccgcctg   3540

gcacccactt agccaaacag gctctgcaga tggcatgggg aggaggttgc actcagccca   3600

tgatcctggt ctctcaaaga cttcaacagc agaaatggag catggtctcc atgaagccag   3660

aacagtgcgt acttctcagg ctacaccttg ccgaggcctc agcagggagt gtggggagga   3720

tgagcagtac agtgcagaga atttacgtcg catctcacgc agtctcagtg gcaccgttgt   3780

ctcagagagg gaggaagctc cggtttcttc ccacagtttt gattcatcaa acgtgaggaa   3840

gcctttggaa accgggcacc gttgttccag ctcctcttcc ctccctgtca tccatgaccc   3900

ttctgtgttt ctcctcggtc cccaactcta ccttccccaa ccacagttcc tgtccccaga   3960

tgtcctgatg cccaccatgg caggggagcc caatagactc ccaggaactt caaggagtgt   4020

ccagcagttt ctggctatgt gtgacagggg tgaaacttcc caaggggcca agtacacagg   4080

aaggactttg aactaccaga gcctccccca tcgctccaga acagacaact cctgggcacc   4140

ctggtcagag accaaccagc atattgggac cagattcctg actactccag ggtgcaatcc   4200

tcaactaacc tacactgcca cactaccaga aagaagcaag ggccttcagg ttcctcacac   4260

tcagtcctgg agtgatcttt tccattcacc ctcccaccct cccattgttc atcctgtgta   4320

cccaccatct agcagtcttc atgtacccct gaggtcagct tggaattcag atcctgttcc   4380

agggtcccga acccctggtc ctcgaagagt agatatgccc ccagatgatg actggaggca   4440

aagcagttat gcctcccact ctggacacag gagaacagtg ggagaggggt ttctgtttgt   4500

tctatcagat gctcccagaa gagagcagat cagggctaga gtcctgcagc acagtcaatg   4560

gtaaaggtta ttcctttcct ttcctggagc tacacctttc tttgtaaaac tgtactgtgg   4620

gccgggcgcg gtggctcaca cctgtaatcc cagcactttg ggaggctgag gcgggtggat   4680

cacgaggtca ggagattgag accatcctgg ccaacatggt gaaaccccgt ctctaccaaa   4740

atacaaaaaa ttagccaggc gtgacggtgc gtgcctgtag tcccaactac tcggaaggct   4800

gaggcaggag aattgcttga acccgggagg cagaggttgc agtgagccga gatcgcacca   4860

ctgcactcca gcttggcaat agagtgagac tccatctcaa aaaacaaaac aaaacaacaa   4920

caaaataaac tactgtggca gcgttggtac cctgcatcac tgccatggtt gtgctattct   4980

catctcaaca tagaattggt gggttctcct aagggtgtca ggaacctcta aaaagatgtg   5040

attctttggg aggggatatt tgaaattcca acttccattc cccctagcaa aaggaagcag   5100

ctgctgttta agggttttat ctgagccact ttaaagatga atccatggta ttactctgga   5160

tactagccat tccttaggat tttaaggtca cattttattc ctggatgctt tatgtcccca   5220

cctccacctg agccctcatc ctctgttccc tactatactc ccaacttcta ctctttgttt   5280

tatccaccta tccctattac ctgacccttt gtcttccctg tctcccatcc ttggggggac   5340

atgtagccct gtggtcatgg ttctgatgac atcatcaggg cagcccccct gcccaggtat   5400

tatggcctgt cagcattccc tgtgccctcc aaaccttagg cctagaatgc ggagctgcca   5460

acataacatt cacccttttg aacagatgga gtcaggcaca ctaacacagc cttctgtcct   5520

caataacaca gccattattg ccacttgctc agtcgtcaat gtaaaccctc agagtcagct   5580

gaactatttt aggccaaaca tactgttttt gtaaagtatt tttcattaat aaatctataa   5640

gacagttcta tttaa                                                    5655


<210>  7085
<211>  772
<212>  PRT
<213>  Homo sapiens

<400>  7085

Met Asp Thr Glu Phe Gly Ala Ser Ser Phe Phe His Ser Pro Ala Ser 
1               5                   10                  15


Cys His Glu Ser His Ser Ser Leu Ser Pro Glu Ser Ser Ala Pro Gln 
            20                  25                  30


His Ser Ser Pro Ser Arg Ser Ala Leu Lys Leu Leu Thr Ser Val Glu 
        35                  40                  45


Val Asp Asn Ile Glu Pro Ser Ala Phe His Arg Gln Gly Leu Pro Lys 
    50                  55                  60


Ala Pro Gly Trp Thr Glu Lys Asn Ser His His Ser Trp Glu Pro Leu 
65                  70                  75                  80


Asp Ala Pro Glu Gly Lys Leu Gln Gly Ser Arg Cys Asp Asn Ser Ser 
                85                  90                  95


Cys Ser Lys Leu Pro Pro Gln Glu Gly Arg Gly Ile Ala Gln Glu Gln 
            100                 105                 110


Leu Phe Gln Glu Lys Lys Asp Pro Ala Asn Pro Ser Pro Val Met Pro 
        115                 120                 125


Gly Ile Ala Thr Ser Glu Arg Gly Asp Glu His Ser Leu Gly Cys Ser 
    130                 135                 140


Pro Ser Asn Ser Ser Ala Gln Pro Ser Leu Pro Leu Tyr Arg Thr Cys 
145                 150                 155                 160


His Pro Ile Met Pro Val Ala Ser Ser Phe Val Leu His Cys Pro Asp 
                165                 170                 175


Pro Val Gln Lys Thr Asn Gln Cys Leu Gln Gly Gln Ser Leu Lys Thr 
            180                 185                 190


Ser Leu Thr Leu Lys Val Asp Arg Gly Ser Glu Glu Thr Tyr Arg Pro 
        195                 200                 205


Glu Phe Pro Ser Thr Lys Gly Leu Val Arg Ser Leu Ala Glu Gln Phe 
    210                 215                 220


Gln Arg Met Gln Gly Val Ser Met Arg Asp Ser Thr Gly Phe Lys Asp 
225                 230                 235                 240


Arg Ser Leu Ser Gly Ser Leu Arg Lys Asn Ser Ser Pro Ser Asp Ser 
                245                 250                 255


Lys Pro Pro Phe Ser Gln Gly Gln Glu Lys Gly His Trp Pro Trp Ala 
            260                 265                 270


Lys Gln Gln Ser Ser Leu Glu Gly Gly Asp Arg Pro Leu Ser Trp Glu 
        275                 280                 285


Glu Ser Thr Glu His Ser Ser Leu Ala Leu Asn Ser Gly Leu Pro Asn 
    290                 295                 300


Gly Glu Thr Ser Ser Gly Gly Gln Pro Arg Leu Ala Glu Pro Asp Ile 
305                 310                 315                 320


Tyr Gln Glu Lys Leu Ser Gln Val Arg Asp Val Arg Ser Lys Asp Leu 
                325                 330                 335


Gly Ser Ser Thr Asp Leu Gly Thr Ser Leu Pro Leu Asp Ser Trp Val 
            340                 345                 350


Asn Ile Thr Arg Phe Cys Asp Ser Gln Leu Lys His Gly Ala Pro Arg 
        355                 360                 365


Pro Gly Met Lys Ser Ser Pro His Asp Ser His Thr Cys Val Thr Tyr 
    370                 375                 380


Pro Glu Arg Asn His Ile Leu Leu His Pro His Trp Asn Gln Asp Thr 
385                 390                 395                 400


Glu Gln Glu Thr Ser Glu Leu Glu Ser Leu Tyr Gln Ala Ser Leu Gln 
                405                 410                 415


Ala Ser Gln Ala Gly Cys Ser Gly Trp Gly Gln Gln Asp Thr Ala Trp 
            420                 425                 430


His Pro Leu Ser Gln Thr Gly Ser Ala Asp Gly Met Gly Arg Arg Leu 
        435                 440                 445


His Ser Ala His Asp Pro Gly Leu Ser Lys Thr Ser Thr Ala Glu Met 
    450                 455                 460


Glu His Gly Leu His Glu Ala Arg Thr Val Arg Thr Ser Gln Ala Thr 
465                 470                 475                 480


Pro Cys Arg Gly Leu Ser Arg Glu Cys Gly Glu Asp Glu Gln Tyr Ser 
                485                 490                 495


Ala Glu Asn Leu Arg Arg Ile Ser Arg Ser Leu Ser Gly Thr Val Val 
            500                 505                 510


Ser Glu Arg Glu Glu Ala Pro Val Ser Ser His Ser Phe Asp Ser Ser 
        515                 520                 525


Asn Val Arg Lys Pro Leu Glu Thr Gly His Arg Cys Ser Ser Ser Ser 
    530                 535                 540


Ser Leu Pro Val Ile His Asp Pro Ser Val Phe Leu Leu Gly Pro Gln 
545                 550                 555                 560


Leu Tyr Leu Pro Gln Pro Gln Phe Leu Ser Pro Asp Val Leu Met Pro 
                565                 570                 575


Thr Met Ala Gly Glu Pro Asn Arg Leu Pro Gly Thr Ser Arg Ser Val 
            580                 585                 590


Gln Gln Phe Leu Ala Met Cys Asp Arg Gly Glu Thr Ser Gln Gly Ala 
        595                 600                 605


Lys Tyr Thr Gly Arg Thr Leu Asn Tyr Gln Ser Leu Pro His Arg Ser 
    610                 615                 620


Arg Thr Asp Asn Ser Trp Ala Pro Trp Ser Glu Thr Asn Gln His Ile 
625                 630                 635                 640


Gly Thr Arg Phe Leu Thr Thr Pro Gly Cys Asn Pro Gln Leu Thr Tyr 
                645                 650                 655


Thr Ala Thr Leu Pro Glu Arg Ser Lys Gly Leu Gln Val Pro His Thr 
            660                 665                 670


Gln Ser Trp Ser Asp Leu Phe His Ser Pro Ser His Pro Pro Ile Val 
        675                 680                 685


His Pro Val Tyr Pro Pro Ser Ser Ser Leu His Val Pro Leu Arg Ser 
    690                 695                 700


Ala Trp Asn Ser Asp Pro Val Pro Gly Ser Arg Thr Pro Gly Pro Arg 
705                 710                 715                 720


Arg Val Asp Met Pro Pro Asp Asp Asp Trp Arg Gln Ser Ser Tyr Ala 
                725                 730                 735


Ser His Ser Gly His Arg Arg Thr Val Gly Glu Gly Phe Leu Phe Val 
            740                 745                 750


Leu Ser Asp Ala Pro Arg Arg Glu Gln Ile Arg Ala Arg Val Leu Gln 
        755                 760                 765


His Ser Gln Trp 
    770


<210>  7086
<211>  957
<212>  DNA
<213>  Homo sapiens

<400>  7086
gcttcctttt gctaggggga atggaagttg gaatttcaaa tatcccctcc caaagaatca     60

catcttttta gaggttcctg acacccttag gagaacccac caattctatg ttgagatgag    120

aatagcacaa ccatggcagt gatgcagggt accaacgctg ccacagtagt ttattttgtt    180

gttgttttgt tttgtttttt gagatggagt ctcactctat tgccaagctg gagtgcagtg    240

gtgcgatctc ggctcactgc aacctctgcc tcccgggttc aagcaattct cctgcctcag    300

ccttccgagt agttgggact acaggcacgc accgtcacgc ctggctaatt ttttgtattt    360

tggtagagac ggggtttcac catgttggcc aggatggtct caatctcctg acctcgtgat    420

ccacccgcct cagcctccca aagtgctggg attacaggtg tgagccaccg cgcccggccc    480

acagtacagt tttacaaaga aaggtgtagc tccaggaaag gaaaggaata acctttacca    540

ttgactgtgc tgcaggactc tagccctgat ctgctctctt ctgggagcat ctgatagaac    600

aaacagaaac ccctctccca ctgttctcct gtgtccagag tgggaggcat aactgctttg    660

cctccagtca tcatctgggg gcatatctac tcttcgagga ccaggggttc gggaccctgg    720

aacaggatct gaattccaag ctgacctcag gggtacatga agactgctag atggtgggta    780

cacaggatga acaatgggag ggtgggaggg tgaatggaaa agatcactcc aggactgagt    840

gtgaggaacc tgaaggccct tgcttctttc tggtagtgtg gcagtgtagg ttagttgagg    900

attgcaccct ggagtagtca ggaatctggt cccaatatgc tggttggggc cccttgg       957


<210>  7087
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  7087

Met Glu Ser His Ser Ile Ala Lys Leu Glu Cys Ser Gly Ala Ile Ser 
1               5                   10                  15


Ala His Cys Asn Leu Cys Leu Pro Gly Ser Ser Asn Ser Pro Ala Ser 
            20                  25                  30


Ala Phe Arg Val Val Gly Thr Thr Gly Thr His Arg His Ala Trp Leu 
        35                  40                  45


Ile Phe Cys Ile Leu Val Glu Thr Gly Phe His His Val Gly Gln Asp 
    50                  55                  60


Gly Leu Asn Leu Leu Thr Ser 
65                  70


<210>  7088
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  7088
gatgaacact caacttgggc aaggaagtga aattctccaa aggtatgatt acctacaaac     60

ctagccactg atattattta agtttgttga tctctaatgg cttgggcttt cctgcctctt    120

ctacttacac attactgcac tagtaccata tgaaaattct caagaaggct tttttcctct    180

tcttgctgat acacatgcat cactttagat tgaaaacaca ctgaattcta ttcaatcaca    240

tactgggggt gagaggaaaa agcaaaccaa tactccatcc catttctttc cttctttctt    300

tgattagtgc agtgggttct gacccaatca gcagcctttg cttctcagat tcctctcaag    360

gctttatgac tcttctcacc ccaggaaacc ctacaacacg cacggccttt cagaactgct    420

acatggaatg gacattcctc tgggctccag ctgaatgttt gtaaataaaa taatgactgc    480

gtgtccttat ttttgctgag tacacagggc ctttcctcac attacaacct tcactttctc    540

cctgcttctt cacctgcatc cagactgggc gatagagtga gaatccaga                589


<210>  7089
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7089

Met Thr Leu Leu Thr Pro Gly Asn Pro Thr Thr Arg Thr Ala Phe Gln 
1               5                   10                  15


Asn Cys Tyr Met Glu Trp Thr Phe Leu Trp Ala Pro Ala Glu Cys Leu 
            20                  25                  30


<210>  7090
<211>  4054
<212>  DNA
<213>  Homo sapiens

<400>  7090
agtcccagaa gaaagaggag agacttgctg aagatctgga tgggacaata gaagtttggg     60

gcacattaaa aagaagcagc aagaacatca acaaaaacct cagatgattc aaacaggctt    120

cttcttggct ttgtggaacc ttttgcagtt gctcagaatt tgagtttttg cttcagagga    180

tgatgagaca aggcaataga gggtgaggag gatcatgttg gattcttgct tctctgtctg    240

cctctccttc cagttggaaa aatcttcagt ccataagaag cattatcaac aagcctgaag    300

aacacatctt accctgatcc tggatgctgt tggagttgag aattacatcc acttcaccag    360

gactttatgg aggctgttca agaaaaatag aaggaagcaa tacttaagga tttctctgtt    420

tgcattagtc ctgtgccatg ttacattttg gagattgttt ggaacaagtg agggagggct    480

ctgtcatctt gatctaggag gatacctgag tcccttgact acacagatga tatttggaag    540

gtggctaaat gtgaacaata atgtcttgga agagaaatta tttttcaggg ggtcgtggta    600

gtgtacaagg gatgtttgca cctcgaagct caacctccat agcccccagc aaaggcctca    660

gcaatgagcc agggcaaaac agctgcttcc tcaacagtgc cctgcaggtt ttgtggcact    720

tggatatctt ccgacgtagc tttaggcagc ttacaactca caagtgcatg ggagattcct    780

gcatcttttg cgctctcaag ggaatcttta accagtttca gtgtagtagt gaaaaagtgc    840

ttccatctga cactctccgc agtgctctgg caaagacttt ccaggatgaa caacgtttcc    900

agctgggaat tatggatgat gctgcagagt gctttgaaaa cctcctgatg agaattcact    960

tccacattgc tgatgaaacc aaagaggata tatgtactgc ccaacactgc atttcccatc   1020

agaaatttgc aatgacattg tttgagcagt gtgtatgtac tagctgtggt gccacttctg   1080

atccgctgcc tttcatccag atggtacatt atatctccac cacttccctt tgcaatcagg   1140

ctatttgtat gctggaaaga cgagagaaac cttcaccaag catgtttggt gagctgctgc   1200

agaatgccag caccatgggg gatctgcgga actgtccaag caactgtgga gagaggatca   1260

ggattcgccg tgtgttgatg aatgctccac agattatcac gattgggctg gtatgggact   1320

cagaccactc agacttagca gaagatgtta tccacagcct gggaacctgc cttaagctgg   1380

gtgatctgtt tttcagagtg acggatgacc gggccaagca atctgaactg tacttagttg   1440

gaatgatctg ttactatggc aaacattatt ctacattctt ttttcaaaca aagattcgca   1500

aatggatgta ttttgatgat gctcatgtca aggagattgg gcccaaatgg aaggatgtgg   1560

tgaccaaatg catcaagggg cattatcagc ccctgctgct gctttatgca gatccccagg   1620

gtaccccagt ttccacccag gacctgcctc cccaagctga gttccagtca tacagcagga   1680

catgctacga cagtgaagat tcagggaggg agccctccat ctcaagtgac actcgaacag   1740

attcctcaac ggagagctat ccctacaaac attcccacca tgagtctgtg gtcagtcact   1800

tctcttctga ttctcagggg acagtcatct ataatgtgga aaatgattcc atgtctcaga   1860

gcagtcggga cacaggacac ctgactgata gtgaatgtaa tcagaaacac acatccaaga   1920

aagggtcact gatagagcgc aagaggagct ctggtcgggt taggaggaaa ggcgatgagc   1980

cccaggcctc gggataccac agtgaaggag aaacactgaa agagaagcag gctcctagaa   2040

atgcctccaa accatccagc agcaccaaca ggctgagaga ttttaaagag acagtcagca   2100

atatgatcca taacagacca tccctggctt ctcagaccaa tgtaggctct cactgcaggg   2160

gcagaggagg agaccagcct gacaaaaaac ctcctaggac cctgccttta cactctcgtg   2220

actgggaaat agagagtacc agcagtgagt caaaatccag ttcttccagc aagtatcgtc   2280

ccacatggag acccaaacga gaatctctga atattgacag tatctttagt aaggacaaaa   2340

ggaagcactg tggctatacc cagcttagcc ccttttctga ggattcagct aaagaattta   2400

taccagatga accaagcaag ccaccttctt acgacattaa atttggtgga ccaagccccc   2460

agtacaagcg ctggggccca gcacggccag gctctcacct tttagagcag cacccccgac   2520

taatccagcg aatggaatct ggctatgaaa gcagtgagag gaacagcagc agccctgtca   2580

gcctggatgc agccctgcct gagagctcaa atgtctacag ggatccaagt gctaagagat   2640

cagctgggtt ggttccttcc tggcgtcata tcccaaagtc gcacagcagt agcatcctgg   2700

aggtagactc cacagcatcc atgggtggct ggacaaagag tcagcctttc tctggtgagg   2760

agatatcttc taaaagtgaa ctggatgaat tgcaggaaga ggtggccagg agggcgcagg   2820

aacaggaact tcgaagaaaa cgggagaagg agttagaggc agcgaaaggg tttaaccctc   2880

atcctagccg cttcatggac ttggatgaac tgcagaatca ggggaggagt gacggctttg   2940

agaggtccct gcaagaggca gagtcagtgt ttgaagagtc actacatctg gaacagaaag   3000

gagactgtgc tgcagctttg gctctctgta atgaagctat ctctaaacta agacttgccc   3060

tgcatggtgc cagctgtagc acgcacagca gagccctagt cgataagaag ttgcaaatca   3120

gtattcgaaa agcacggagc ctgcaggatc gcatgcagca gcagcaatca ccacagcagc   3180

cgtcgcagcc ctcagcctgc ctcccaacac aggcggggac tctctctcag ccaacaaggt   3240

agtgcttggg aaccatgtta gtttatgaat gccaggggaa gaaatgacca tgagtattct   3300

gtagcaagag ctctcattgt cttggcgact gaaggggaga gaggagtcct ctgaaaagat   3360

tttcttcttt caggtcagac atacagtgaa aagctcattg tactgctggt ccttatctta   3420

ataattccta ggatgcaaaa agtacagcat aataagacca tttgtccaca tttcccatgg   3480

gtaactttag ccctggactt gtgtaataac gcgattatta tatttgtata tattatgttc   3540

ttagacatgg caatccaggc tacatttcat gttgtagtag ctaccatgtg atttattttg   3600

ggatttcagt gcttcctatc cttatggaag cagagaaagc agtctttctt gctctgattg   3660

caccatagag aagagacaca aagattccct ttgctttgct tctttatggt caggactagg   3720

aaagaagttc cagtagtcat tgttgtagtt ctcacatctt agccctggaa tttggctttt   3780

acttagaata gatgaattta aataaacatt aatttggacc gttaataatt ctgagtagtt   3840

ttcaaaatat aaattagtaa aagcagttaa catttttttt tttttttttt ttttggagac   3900

aggatcttgc tttttcaccc aggctggagt gcagtggcac gatcacagct tactgcagcc   3960

tcaacctcct gggttcaatg ttcaaaaggc aaatgttcaa aaatagttaa ctgctaggca   4020

tggtagctca cgcctgtaat cccagaattt tggg                               4054


<210>  7091
<211>  893
<212>  PRT
<213>  Homo sapiens

<400>  7091

Met Ser Trp Lys Arg Asn Tyr Phe Ser Gly Gly Arg Gly Ser Val Gln 
1               5                   10                  15


Gly Met Phe Ala Pro Arg Ser Ser Thr Ser Ile Ala Pro Ser Lys Gly 
            20                  25                  30


Leu Ser Asn Glu Pro Gly Gln Asn Ser Cys Phe Leu Asn Ser Ala Leu 
        35                  40                  45


Gln Val Leu Trp His Leu Asp Ile Phe Arg Arg Ser Phe Arg Gln Leu 
    50                  55                  60


Thr Thr His Lys Cys Met Gly Asp Ser Cys Ile Phe Cys Ala Leu Lys 
65                  70                  75                  80


Gly Ile Phe Asn Gln Phe Gln Cys Ser Ser Glu Lys Val Leu Pro Ser 
                85                  90                  95


Asp Thr Leu Arg Ser Ala Leu Ala Lys Thr Phe Gln Asp Glu Gln Arg 
            100                 105                 110


Phe Gln Leu Gly Ile Met Asp Asp Ala Ala Glu Cys Phe Glu Asn Leu 
        115                 120                 125


Leu Met Arg Ile His Phe His Ile Ala Asp Glu Thr Lys Glu Asp Ile 
    130                 135                 140


Cys Thr Ala Gln His Cys Ile Ser His Gln Lys Phe Ala Met Thr Leu 
145                 150                 155                 160


Phe Glu Gln Cys Val Cys Thr Ser Cys Gly Ala Thr Ser Asp Pro Leu 
                165                 170                 175


Pro Phe Ile Gln Met Val His Tyr Ile Ser Thr Thr Ser Leu Cys Asn 
            180                 185                 190


Gln Ala Ile Cys Met Leu Glu Arg Arg Glu Lys Pro Ser Pro Ser Met 
        195                 200                 205


Phe Gly Glu Leu Leu Gln Asn Ala Ser Thr Met Gly Asp Leu Arg Asn 
    210                 215                 220


Cys Pro Ser Asn Cys Gly Glu Arg Ile Arg Ile Arg Arg Val Leu Met 
225                 230                 235                 240


Asn Ala Pro Gln Ile Ile Thr Ile Gly Leu Val Trp Asp Ser Asp His 
                245                 250                 255


Ser Asp Leu Ala Glu Asp Val Ile His Ser Leu Gly Thr Cys Leu Lys 
            260                 265                 270


Leu Gly Asp Leu Phe Phe Arg Val Thr Asp Asp Arg Ala Lys Gln Ser 
        275                 280                 285


Glu Leu Tyr Leu Val Gly Met Ile Cys Tyr Tyr Gly Lys His Tyr Ser 
    290                 295                 300


Thr Phe Phe Phe Gln Thr Lys Ile Arg Lys Trp Met Tyr Phe Asp Asp 
305                 310                 315                 320


Ala His Val Lys Glu Ile Gly Pro Lys Trp Lys Asp Val Val Thr Lys 
                325                 330                 335


Cys Ile Lys Gly His Tyr Gln Pro Leu Leu Leu Leu Tyr Ala Asp Pro 
            340                 345                 350


Gln Gly Thr Pro Val Ser Thr Gln Asp Leu Pro Pro Gln Ala Glu Phe 
        355                 360                 365


Gln Ser Tyr Ser Arg Thr Cys Tyr Asp Ser Glu Asp Ser Gly Arg Glu 
    370                 375                 380


Pro Ser Ile Ser Ser Asp Thr Arg Thr Asp Ser Ser Thr Glu Ser Tyr 
385                 390                 395                 400


Pro Tyr Lys His Ser His His Glu Ser Val Val Ser His Phe Ser Ser 
                405                 410                 415


Asp Ser Gln Gly Thr Val Ile Tyr Asn Val Glu Asn Asp Ser Met Ser 
            420                 425                 430


Gln Ser Ser Arg Asp Thr Gly His Leu Thr Asp Ser Glu Cys Asn Gln 
        435                 440                 445


Lys His Thr Ser Lys Lys Gly Ser Leu Ile Glu Arg Lys Arg Ser Ser 
    450                 455                 460


Gly Arg Val Arg Arg Lys Gly Asp Glu Pro Gln Ala Ser Gly Tyr His 
465                 470                 475                 480


Ser Glu Gly Glu Thr Leu Lys Glu Lys Gln Ala Pro Arg Asn Ala Ser 
                485                 490                 495


Lys Pro Ser Ser Ser Thr Asn Arg Leu Arg Asp Phe Lys Glu Thr Val 
            500                 505                 510


Ser Asn Met Ile His Asn Arg Pro Ser Leu Ala Ser Gln Thr Asn Val 
        515                 520                 525


Gly Ser His Cys Arg Gly Arg Gly Gly Asp Gln Pro Asp Lys Lys Pro 
    530                 535                 540


Pro Arg Thr Leu Pro Leu His Ser Arg Asp Trp Glu Ile Glu Ser Thr 
545                 550                 555                 560


Ser Ser Glu Ser Lys Ser Ser Ser Ser Ser Lys Tyr Arg Pro Thr Trp 
                565                 570                 575


Arg Pro Lys Arg Glu Ser Leu Asn Ile Asp Ser Ile Phe Ser Lys Asp 
            580                 585                 590


Lys Arg Lys His Cys Gly Tyr Thr Gln Leu Ser Pro Phe Ser Glu Asp 
        595                 600                 605


Ser Ala Lys Glu Phe Ile Pro Asp Glu Pro Ser Lys Pro Pro Ser Tyr 
    610                 615                 620


Asp Ile Lys Phe Gly Gly Pro Ser Pro Gln Tyr Lys Arg Trp Gly Pro 
625                 630                 635                 640


Ala Arg Pro Gly Ser His Leu Leu Glu Gln His Pro Arg Leu Ile Gln 
                645                 650                 655


Arg Met Glu Ser Gly Tyr Glu Ser Ser Glu Arg Asn Ser Ser Ser Pro 
            660                 665                 670


Val Ser Leu Asp Ala Ala Leu Pro Glu Ser Ser Asn Val Tyr Arg Asp 
        675                 680                 685


Pro Ser Ala Lys Arg Ser Ala Gly Leu Val Pro Ser Trp Arg His Ile 
    690                 695                 700


Pro Lys Ser His Ser Ser Ser Ile Leu Glu Val Asp Ser Thr Ala Ser 
705                 710                 715                 720


Met Gly Gly Trp Thr Lys Ser Gln Pro Phe Ser Gly Glu Glu Ile Ser 
                725                 730                 735


Ser Lys Ser Glu Leu Asp Glu Leu Gln Glu Glu Val Ala Arg Arg Ala 
            740                 745                 750


Gln Glu Gln Glu Leu Arg Arg Lys Arg Glu Lys Glu Leu Glu Ala Ala 
        755                 760                 765


Lys Gly Phe Asn Pro His Pro Ser Arg Phe Met Asp Leu Asp Glu Leu 
    770                 775                 780


Gln Asn Gln Gly Arg Ser Asp Gly Phe Glu Arg Ser Leu Gln Glu Ala 
785                 790                 795                 800


Glu Ser Val Phe Glu Glu Ser Leu His Leu Glu Gln Lys Gly Asp Cys 
                805                 810                 815


Ala Ala Ala Leu Ala Leu Cys Asn Glu Ala Ile Ser Lys Leu Arg Leu 
            820                 825                 830


Ala Leu His Gly Ala Ser Cys Ser Thr His Ser Arg Ala Leu Val Asp 
        835                 840                 845


Lys Lys Leu Gln Ile Ser Ile Arg Lys Ala Arg Ser Leu Gln Asp Arg 
    850                 855                 860


Met Gln Gln Gln Gln Ser Pro Gln Gln Pro Ser Gln Pro Ser Ala Cys 
865                 870                 875                 880


Leu Pro Thr Gln Ala Gly Thr Leu Ser Gln Pro Thr Arg 
                885                 890


<210>  7092
<211>  509
<212>  DNA
<213>  Homo sapiens

<400>  7092
cttgccccac agataccctc gtgattagag gtcttttgct ggaggttgac tgtgctgtct     60

ggctaaatgt gaacaataat gtcttggaag agaaattatt tttcaggggg tcgtggtagt    120

gtacaaggga tgtttgcacc tcgaagctca acctccatag cccccagcaa aggcctcagc    180

aatgagccag ggcaaaacag ctgcttcctc aacagtgccc tgcaggtttt gtggcacttg    240

gatatcttcc gacgtagctt taggcagctt acaactcaca agtgcatggg agattcctgc    300

atcttttgcg ctctcaaggg aatctttaac cagtttcagt gtagtagtga aaaagtgctt    360

ccatctgaca ctctccgcag tgctctggca aagactttcc aggatgaaca acgtttccag    420

ctgggaatta tggatgatgc tgcagagtgc tttctgtttt tcagagtgac ggatgaccgg    480

gccaagcaat ctgaactgta cttagttgg                                      509


<210>  7093
<211>  142
<212>  PRT
<213>  Homo sapiens

<400>  7093

Met Ser Trp Lys Arg Asn Tyr Phe Ser Gly Gly Arg Gly Ser Val Gln 
1               5                   10                  15


Gly Met Phe Ala Pro Arg Ser Ser Thr Ser Ile Ala Pro Ser Lys Gly 
            20                  25                  30


Leu Ser Asn Glu Pro Gly Gln Asn Ser Cys Phe Leu Asn Ser Ala Leu 
        35                  40                  45


Gln Val Leu Trp His Leu Asp Ile Phe Arg Arg Ser Phe Arg Gln Leu 
    50                  55                  60


Thr Thr His Lys Cys Met Gly Asp Ser Cys Ile Phe Cys Ala Leu Lys 
65                  70                  75                  80


Gly Ile Phe Asn Gln Phe Gln Cys Ser Ser Glu Lys Val Leu Pro Ser 
                85                  90                  95


Asp Thr Leu Arg Ser Ala Leu Ala Lys Thr Phe Gln Asp Glu Gln Arg 
            100                 105                 110


Phe Gln Leu Gly Ile Met Asp Asp Ala Ala Glu Cys Phe Leu Phe Phe 
        115                 120                 125


Arg Val Thr Asp Asp Arg Ala Lys Gln Ser Glu Leu Tyr Leu 
    130                 135                 140


<210>  7094
<211>  1039
<212>  DNA
<213>  Homo sapiens

<400>  7094
aacaaagagg tgaatgagca gaatgggtca tgtacatccc actgatgtgt gctgatgtga     60

caaagagaga aggcaggtag aagagctatc tgaacgttgc taacagaggg cctggggagg    120

agggacgggc acgaccgcat ctgctcctct gtcctgtgtg cgtgtttggc cacctgatgc    180

caactccatg atggcacatt tgtcttatta agtgagttgg cttcctggtc tgaaccctcc    240

ataagccctg gctgggaatt ttcctcactg tgaccttgtg agcagtccct ggttaccctc    300

aaggattgtg ccaagcaggc tctgggttaa catcttggag agtacagagt aggctgataa    360

tcagcctatg ctcaacagca cacccaagag ttgaagattt ctgatggcat ccctggggtg    420

ctcagcagtg gcctttgtct gcacccatct tcattacatg ttaataccac cagagacact    480

ttgaggtcac tggaaggact gagcgcattc aggagcctgg aggaactcat cttggacaac    540

aatcagctgg gggacgacct tgtgttgcca gggttaccca gactgcatac cttaaccctc    600

aacaagaacc gaatcactga tttggagaac ctgctggatc acttggcaga agtgacacca    660

gctctggagt acctcagtct gctgggcaac gtggcctgtc ccaacgagct ggtcagcttg    720

gaaaaggatg aggaagacta caagagatac agatgctttg ttctgtacaa gctgcccaac    780

ttgaaatttc tggatgccca gaaagtaacc agacaagaac gagaggaggc gttggtcaga    840

ggagtcttca tgaaggtggt gaagcccaag gtgagaggtg tcctggggaa gtgtcgctac    900

gtttactatg ggaaaaactc agagggcaac aggtttatcc gagatgacca gctctgaagc    960

caacttctgt ataccttcac ccatttcatg aaaataaaat caaaagggaa atcaaaaata   1020

aagaaaacgc taaagaaaa                                                1039


<210>  7095
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  7095

Met Leu Cys Ser Val Gln Ala Ala Gln Leu Glu Ile Ser Gly Cys Pro 
1               5                   10                  15


Glu Ser Asn Gln Thr Arg Thr Arg Gly Gly Val Gly Gln Arg Ser Leu 
            20                  25                  30


His Glu Gly Gly Glu Ala Gln Gly Glu Arg Cys Pro Gly Glu Val Ser 
        35                  40                  45


Leu Arg Leu Leu Trp Glu Lys Leu Arg Gly Gln Gln Val Tyr Pro Arg 
    50                  55                  60


<210>  7096
<211>  816
<212>  DNA
<213>  Homo sapiens

<400>  7096
gttgaagaaa gaggatctgg ctgaaagacc cgcaactttc acttgttgag aacctttagc     60

cagcgccggc gtgcatgtgt tttagtttta ttctttttcc cttgccccca aagccgtgga    120

gtacctgctg ttgctctcat gcctcttgcc aacagtggca tctgctcagt gtagccatca    180

agaatttgaa tgtcaatatc tttgccttga aatgaatgga aaagtatttg tcactcagcg    240

gcaatcattc ttcaaataaa aggtcactgg aaggactgag cgcattcagg agcctggagg    300

aactcatctt ggacaacaat cagctggggg acgaccttgt gttgccaggg ttacccagac    360

tgcatacctt aaccctcaac aagaaccgaa tcactgattt ggagaacctg ctggatcact    420

tggcagaagt gacaccagct ctggagtacc tcagtctgct gggcaacgtg gcctgtccca    480

acgagctggt cagcttggaa aaggatgagg aagactacaa gagatacaga tgctttgttc    540

tgtacaagct gcccaacttg aaatttctgg atgcccagaa agtaaccaga caagaacgag    600

aggaggcgtt ggtcagagga gtcttcatga aggtggtgaa gcccaaggtg agaggtgtcc    660

tggggaagtg tcgctacgtt tactatggga aaaactcaga gggcaacagg tttatccgag    720

atgaccagct ctgaagccaa cttctgtata ccttcaccca tttcatgaaa ataaaatcaa    780

aagggaaatc aaaaataaag aaaacgctaa agaaaa                              816


<210>  7097
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  7097

Met Glu Lys Tyr Leu Ser Leu Ser Gly Asn His Ser Ser Asn Lys Arg 
1               5                   10                  15


Ser Leu Glu Gly Leu Ser Ala Phe Arg Ser Leu Glu Glu Leu Ile Leu 
            20                  25                  30


Asp Asn Asn Gln Leu Gly Asp Asp Leu Val Leu Pro Gly Leu Pro Arg 
        35                  40                  45


Leu His Thr Leu Thr Leu Asn Lys Asn Arg Ile Thr Asp Leu Glu Asn 
    50                  55                  60


Leu Leu Asp His Leu Ala Glu Val Thr Pro Ala Leu Glu Tyr Leu Ser 
65                  70                  75                  80


Leu Leu Gly Asn Val Ala Cys Pro Asn Glu Leu Val Ser Leu Glu Lys 
                85                  90                  95


Asp Glu Glu Asp Tyr Lys Arg Tyr Arg Cys Phe Val Leu Tyr Lys Leu 
            100                 105                 110


Pro Asn Leu Lys Phe Leu Asp Ala Gln Lys Val Thr Arg Gln Glu Arg 
        115                 120                 125


Glu Glu Ala Leu Val Arg Gly Val Phe Met Lys Val Val Lys Pro Lys 
    130                 135                 140


Val Arg Gly Val Leu Gly Lys Cys Arg Tyr Val Tyr Tyr Gly Lys Asn 
145                 150                 155                 160


Ser Glu Gly Asn Arg Phe Ile Arg Asp Asp Gln Leu 
                165                 170


<210>  7098
<211>  3923
<212>  DNA
<213>  Homo sapiens

<400>  7098
agatgccact gtgggcactg gcagaactgg gccccctgta gatcagatag aaacaaatgg     60

gaagctctgg gccattgcct tcaaaaggct ttcttattcc agagaggttt ttgacataat    120

cctcccctcc ccaccagcct ctgctgtgac cagcttctta cttgaattac ccttcagctc    180

cctcgctcag cttcatgctc agcatttgcc cagactctga cctcttctcc attgggatct    240

ttttcttggt ctcttggttc cagactcacc ctcatcccta ccttgccttt tgttttcctc    300

ccaatttctt ggcttctggc tctagacagg atatggctgt tcctgctttc aaacctgtct    360

attattccca acttaatctg tctgtcagtg acaccttctc tcttgcttta ctgaaaggca    420

tggcacctta atctgtgaga ggggtgggaa gcttcagcct tctacctggt tctttagttt    480

ctctaactta atccttcaga agatggcaag tctttacttt tggattctgg caatgtggcc    540

cacactttcg tgttgaatta cagtcatggt atgtagtttt ttttttgttt gtttgagaca    600

gagtctggct ctgtcgccca ggctggagtg gagtggcacg atctcggctc actgcaagct    660

ccgcctcctg ggctcacgcc attctcctgc cttagcctcc agaatagctg ggactacagg    720

cacccgccac catgcctgga gaagtttttg tatttttagt ggagacaggg tttcaccatg    780

ttaaccagga tggtctcgat ctcctgacct cgtgatccac ccgtctcggc ctcccaaagt    840

gctgggatta caggcgtgag ccactgcgcc cagcccatgg cttctagtga ggacgttgcc    900

agctccccgg agcgccacta cacgcccttg ccttctgctt ccagggaact caccagtcac    960

caaggtgtcc tggggaagtg tcgctacgtt tactatggga aaaactcaga gggcaacagg   1020

tttatccgag atgaccagct ctgaagccaa cttctgtata ccttcaccca tttcatgaaa   1080

ataaaatcaa aagggaaatc aaaaataaag aaaacgctaa agaaaaaaca atagcccaca   1140

ttgcctctct ttgggaaaag ctatgacttc agcttttggt accttccgct gactttgcca   1200

ggcctgtcaa gatgatcctt ctgccttaga ctgagtggtc acatagagat tgacatgatt   1260

gcccttaagc aggtctcatc caccagggtg acagacagcg gtggcaaagc aacagggctg   1320

acagcatgaa caccatgata gattgcctgg tcctgccact gctcacaggg gagcagaggt   1380

cacacctggg gcctccctgg acatgctcag tggctgcagt caagtgagaa agactgtcct   1440

cagctcgcct attgaattga aatccctctg ataccatcgt gctgtgggct tatttttagt   1500

gaaatagtca cagtttaggg gatggccatt ctccctcact ccttttaaat cttaacgtcc   1560

tgtattctgc atatacatag ctcccgtctc ttcccctcca ccttccttta gcatcgattt   1620

tatgacaggt ggtgcatttc agtttgcagt ttttcggaga acaaggtata acttcccagc   1680

caggtcatac atttatggct ggcttcatgt tgctacaatc cctttattgg cgtaaatagc   1740

tttccctaaa tccctgacta caaaagcgtg gacttttatc ttgtttcatt caactctaaa   1800

tccacttctt gccctgaata tgatgcagtg taaggcataa ggcatctttc tcagcatgag   1860

ggtttggttg caccagggac tcttatttat taatttattt ttaaccgtac acacttccag   1920

tgatgcctgt ggccatactt gtgcgtgggg ctggcttgct cctttgggtg ctatttaaag   1980

ggagtgaggt gatgaaagat agagtgaagg gtcaggaggt taaaaaacaa aattaagact   2040

gttgaaaaca cccaccagac caaagagttt ttatagaagg cacaaacctt ttggattttg   2100

catctttgtc atgacctctc agaaatcaaa tccacaggtt gtgagacagt gctctgtctt   2160

cctgtatgct tggctgtgca ctagcactaa tgtcacaagg aacataagtg tgatcattgc   2220

tagttgggtg actcaaagtt tatctaactt gctggtgcac cagtcaaatc actctagaag   2280

atgttcaaaa ggttgattga ttgttcttga cacgatagtg tttatttttc tgcttcttcc   2340

atttagacca agtgttcatt gtcctcccag tattaggtca gtttgatgac agcaaaacct   2400

gaaagagaat ccctccaagt tatagatact gagggactag gagctgctat tgtaaaacta   2460

tggggactca gaatccctaa gctgcccaag gagaacctac tttctcagct ctagcccgtt   2520

tacatagcct ctggcccact gagtcaacac aggccttgaa tgacatgtat tgaggctggc   2580

aggagtccct gtttgagatt acacaacctt tgttaatcag ttctttagac aagttaacat   2640

taaaatcctc aaaaccatga aaaattggag aatgttgaat gtttgcattt atctctcaaa   2700

tccattagta actggatttg agtacctttt ctctgtttga tctacaaaac agcactggaa   2760

aaatgcttta aattatctgc atttggtccc accctgggtc attgtttaga agcatcaaca   2820

catgttttct ccctggcata atatgggcag ccagaattct gtgcaagggc agctagacga   2880

gtcagatgtc atatccaatc tagccacaca tatatccttg tctttataaa aggctttaac   2940

cctgcctcaa acaataaaaa agcacttgtg aactgaccac agaatttttc catctttatt   3000

tttcttactt gtttactttt tttaatgtca gaaccatttg tatcatgcgc aggaatgtct   3060

ccctcaatgt gagctttgga ggcaaaacat atttttggag tgagttattg accacattgt   3120

ttccctctct ttgggttgtt tattttcttc cagaatggtg taataacttt aattaagatt   3180

agctttaatt ataaattacc taaaggccat cactaaggta tattcatctt attgatagaa   3240

ttatagtcag ctttgtttct cttaagcagg gatagtgata atgaagtgct gggttggtta   3300

cagttccact gtgtgttaac caaaatttgc tgtgctagag ctagactttg gtctgaattg   3360

gcagaggtag aacccatgtt gcatgtttat cctaaatctg taggaatttc ccaaaccttg   3420

tttttcaaag ttgagaagta gaaagtaata aattcaatca gggcccagac atgttttgta   3480

ccccctttac cctttggtct ttcttccttt tatcctattc cactgagctt gttctttggg   3540

gattgtggtg cctgacatca ctgtctttcc tcccctagga cactgacttg agtggagaga   3600

cctcggcaat tcaaggctgt cctgcagctc tctgttgcct cagcaatgtc aggacgactg   3660

tctctttcct aagtaacata attttaaaga acaatttgtt cctcagggaa taatgtcttg   3720

gattgtgggg aatcctatta aaagtacaac tattgcagtc atttgctttt acttttacca   3780

gcctcactca taaaccctcc atctgtttgt tgctttaaat agaagcacat tataagagat   3840

tatcacttga tcaggctgca tgtctgagtg ttgtgtgttt tcacatactc atgtatacta   3900

aggaataaaa gaaagcaaac cac                                           3923


<210>  7099
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  7099

Met Ala Ser Ser Glu Asp Val Ala Ser Ser Pro Glu Arg His Tyr Thr 
1               5                   10                  15


Pro Leu Pro Ser Ala Ser Arg Glu Leu Thr Ser His Gln Gly Val Leu 
            20                  25                  30


Gly Lys Cys Arg Tyr Val Tyr Tyr Gly Lys Asn Ser Glu Gly Asn Arg 
        35                  40                  45


Phe Ile Arg Asp Asp Gln Leu 
    50                  55


<210>  7100
<211>  672
<212>  DNA
<213>  Homo sapiens

<400>  7100
ggaacaagct tgaaatagcc aagagctaga cacaaaagcc agtgctgcag tagcctagag     60

actgtggaag agaggaggct tggggcattt actaagtgca gacgtggaaa tgttggcatg    120

tggatagacc ctgtaccaaa aacccagcag aagattcaga gtccctgaga tgcttcctcc    180

tcatcttctt cgccaagcac ctcttgtcac tgatcttgga agttagaggt gggaaaaggc    240

aggtgtcctg gggaagtgtc gctacgttta ctatgggaaa aactcagagg gcaacaggtt    300

tatccgagat gaccagctct gaagccaact tctgtatacc ttcacccatt tcatgaaaat    360

aaaatcaaaa gggaaatcaa aaataaagaa aacgctaaag aaaaaacaat agcccacatt    420

gcctctcttt gggaaaagct atgacttcag cttttggtac cttccgctga ctttgccagg    480

cctgtcaaga tgatccttct gccttagact gagtggtcac atagagattg acatgattgc    540

ccttaagcag gtctcatcca ccagggtgac agacagcggt ggcaaagcaa cagggctgac    600

agcatgaaca ccatgataga ttgcctggtc ctgccactgc tcacagggga gcagaggtca    660

cacctggggc ct                                                        672


<210>  7101
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7101

Ser Trp Lys Leu Glu Val Gly Lys Gly Arg Cys Pro Gly Glu Val Ser 
1               5                   10                  15


Leu Arg Leu Leu Trp Glu Lys Leu Arg Gly Gln Gln Val Tyr Pro Arg 
            20                  25                  30


<210>  7102
<211>  355
<212>  DNA
<213>  Homo sapiens

<400>  7102
tgcagacgtg gaaatgttgg catgtggata gaccctgtac caaaaaccca gcagaagatt     60

cagagtccct gagatgcttc ctcctcatct tcttcgccaa gcacctcttg tcactgatct    120

tggaagttag aggtgggaaa aggcagcccc agccctgaga ttgctccagc ctgttcttca    180

cctgcagtgc caggtgtcct ggggaagtgt cgctacgttt actatgggaa aaactcagag    240

ggcaacaggt ttatccgaga tgaccagctc tgaagccaac ttctgtatac cttcacccat    300

ttcatgaaaa taaaatcaaa agggaaatca aaaataaaga aaacgctaaa gaaaa         355


<210>  7103
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  7103

Ser Trp Lys Leu Glu Val Gly Lys Gly Ser Pro Ser Pro Glu Ile Ala 
1               5                   10                  15


Pro Ala Cys Ser Ser Pro Ala Val Pro Gly Val Leu Gly Lys Cys Arg 
            20                  25                  30


Tyr Val Tyr Tyr Gly Lys Asn Ser Glu Gly Asn Arg Phe Ile Arg Asp 
        35                  40                  45


Asp Gln Leu 
    50


<210>  7104
<211>  570
<212>  DNA
<213>  Homo sapiens

<400>  7104
agctgaaaga ggaggtggtg ttcaatggga atcacaaagg ctatggtaga agtgagtaat     60

gagagctggg ctcgagccct ggtctgagtt cagtgtggat gtttaaaggc gaccattctt    120

aagaggcaag agaattcgat actgggttca aatctcaatt ttattttaaa agtgcatcag    180

taacttgtag ctcatttgat ggcctgcagc ccagcttgtt tagaaatccc ttctattctc    240

tctggtactc caagtcccaa agaatctgtt ctgatggtgt ggttacacaa ccagccaagc    300

acagccttag gttgctctca actcagaact caccctatca cacgttgacg aatgcaagag    360

cctgttagag acactggaac ccaagatggt gtcctgggga agtgtcgcta cgtttactat    420

gggaaaaact cagagggcaa caggtttatc cgagatgacc agctctgaag ccaacttctg    480

tataccttca cccatttcat gaaaataaaa tcaaaaggga aatcaaaaat aaagaaaacg    540

ctaaagaaaa aacaatagcc cacattgcct                                     570


<210>  7105
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  7105

Met Gln Glu Pro Val Arg Asp Thr Gly Thr Gln Asp Gly Val Leu Gly 
1               5                   10                  15


Lys Cys Arg Tyr Val Tyr Tyr Gly Lys Asn Ser Glu Gly Asn Arg Phe 
            20                  25                  30


Ile Arg Asp Asp Gln Leu 
        35


<210>  7106
<211>  276
<212>  DNA
<213>  Homo sapiens

<400>  7106
aatgggtgtg aatctctgtg tgctcatata catatgcttg attatatgat catctcgtgg     60

aggacatgtg acacgggaag acaatagggc acatgatatg ctctttgatc taaggtgtcc    120

tggggaagtg tcgctacgtt tactatggga aaaactcaga gggcaacagg tttatccgag    180

atgaccagct ctgaagccaa cttctgtata ccttcaccca tttcatgaaa ataaaatcaa    240

aagggaaatc aaaaataaag aaaacgctaa agaaaa                              276


<210>  7107
<211>  370
<212>  DNA
<213>  Homo sapiens

<400>  7107
atacacccca aagaactgaa aacaagaact caaacagata cttgtacacc tatgttcata     60

gcagccttat tcacatggac aaaagatgaa gtttcattct tgtcgcccag gctggagtgc    120

agtggtgcgt tctcggctca ctgcaacctc cgcctccccg gctcaagcga ttctcctgtc    180

tcagcctccc aagtagctgg aaatacaggt gtcctgggga agtgtcgcta cgtttactat    240

gggaaaaact cagagggcaa caggtttatc cgagatgacc agctctgaag ccaacttctg    300

tataccttca cccatttcat gaaaataaaa tcaaaaggga aatcaaaaat aaagaaaacg    360

ctaaagaaaa                                                           370


<210>  7108
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  7108

Met Phe Ile Ala Ala Leu Phe Thr Trp Thr Lys Asp Glu Val Ser Phe 
1               5                   10                  15


Leu Ser Pro Arg Leu Glu Cys Ser Gly Ala Phe Ser Ala His Cys Asn 
            20                  25                  30


Leu Arg Leu Pro Gly Ser Ser Asp Ser Pro Val Ser Ala Ser Gln Val 
        35                  40                  45


Ala Gly Asn Thr Gly Val Leu Gly Lys Cys Arg Tyr Val Tyr Tyr Gly 
    50                  55                  60


Lys Asn Ser Glu Gly Asn Arg Phe Ile Arg Asp Asp Gln Leu 
65                  70                  75


<210>  7109
<211>  672
<212>  DNA
<213>  Homo sapiens

<400>  7109
taaaataggt ttttctaaaa atagaagaaa ataaaaatgc aggtggcaaa aacaaaacag     60

atttttcctt gataatccta cagagctttc ataataacta tggaagtgat ttcttatggg    120

catttagaat aaataatgag ttgattaaaa agttcaaccc tattgtaggg gcatttttca    180

ttgttaagtc tcctacaatc tccttgaatg agaggagagc cttatacgga gccacagagt    240

tacttaaagt aaaactgaaa atggaaatca aatgcattct gaccagagaa agagagttca    300

ggattcctgt aagaagccat ttaatgggag gctcttgttc ctgtccatgt ggtgtttttt    360

tttgtttttg tttttttgtt tttttgagac ggtgtctctc cctgtcgccc aggctggagt    420

gcactggcgc gatctcggct cactgcaagc tccacctccc gggttcacgc cattctcctg    480

cctcagcctc ccgagtagct gggactacag gtgtcctggg gaagtgtcgc tacgtttact    540

atgggaaaaa ctcagagggc aacaggttta tccgagatga ccagctctga agccaacttc    600

tgtatacctt cacccatttc atgaaaataa aatcaaaagg gaaatcaaaa ataaagaaaa    660

cgctaaagaa aa                                                        672


<210>  7110
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  7110

Met Glu Ile Lys Cys Ile Leu Thr Arg Glu Arg Glu Phe Arg Ile Pro 
1               5                   10                  15


Val Arg Ser His Leu Met Gly Gly Ser Cys Ser Cys Pro Cys Gly Val 
            20                  25                  30


Phe Phe Cys Phe Cys Phe Phe Val Phe Leu Arg Arg Cys Leu Ser Leu 
        35                  40                  45


Ser Pro Arg Leu Glu Cys Thr Gly Ala Ile Ser Ala His Cys Lys Leu 
    50                  55                  60


His Leu Pro Gly Ser Arg His Ser Pro Ala Ser Ala Ser Arg Val Ala 
65                  70                  75                  80


Gly Thr Thr Gly Val Leu Gly Lys Cys Arg Tyr Val Tyr Tyr Gly Lys 
                85                  90                  95


Asn Ser Glu Gly Asn Arg Phe Ile Arg Asp Asp Gln Leu 
            100                 105


<210>  7111
<211>  592
<212>  DNA
<213>  Homo sapiens

<400>  7111
acattccaag atactctaga agaattagca tgtgcttata tgataatatg cacaaataac     60

acaatttatg acctatccca accacaaagt gacaaattaa cacttagcat tataattacc    120

caaaggatgg gaactcccaa tgctgggaaa tttcaggtag acttgtagga agacaatatt    180

ttgaacagtg gttgtggctt tcaatgttct ttgggtcatt tgaggggttg ctgatgcatt    240

agaagaagta atacacaaca ctgtaccaca agccgatggt ccagttgtca tataaacagg    300

ttttgctgtc atcaaactga cctaatactg ggaggacaat gaacacttgg tctaaatgga    360

agaagcagaa aaataaacac tatcgtgtca agaacaatca atcaaccttt tgaacatctt    420

ctagagtgat ttgactggtg caccagcaag ttagataaac tttgagtcac ccaactagca    480

atgatcacac ttatgttcct tgtgacatta gtgctagtgc acagccaagc atacaggaag    540

acagagcact gtctcacaac ctgtggattt gatttctgag aggtcatgac aa            592


<210>  7112
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7112

Met Ile Ile Cys Thr Asn Asn Thr Ile Tyr Asp Leu Ser Gln Pro Gln 
1               5                   10                  15


Ser Asp Lys Leu Thr Leu Ser Ile Ile Ile Thr Gln Arg Met Gly Thr 
            20                  25                  30


Pro Asn Ala Gly Lys Phe Gln Val Asp Leu 
        35                  40


<210>  7113
<211>  6397
<212>  DNA
<213>  Homo sapiens

<400>  7113
cgcagcccgg ggcgagcggg gcgcgggccg gggaggggga gctgcccgcg cactccatcc     60

ccctcccccc cgggcgggcg gcggcggctc gctgtatata tctcggcgca ccccgccagg    120

tcgcgcacag cgccccgagc ccaggcgcct ccccgccccc ctcccgcgct ccgcggcggc    180

ggcggcggcg gcagcagtag cagcaatatg gctgttgatg ggtgtttggg gtggcgctgg    240

cggcgggagg agctcccccg agcccctgcg ccggctgccc gttgctagct atggcaaatg    300

gtggcggcgg cggcggcggc agcagcggcg gcggcggcgg cggcggaggc agcagtctta    360

gaatgagtag caatatccac gcgaaccatc tcagcctaga cgcgtcctcc tcctcctcct    420

cctcctcttc ctcttcttct tcttcctcct cctcttcctc ctcgtcctcg gtccacgagc    480

ccaagatgga tgcgctcatc atcccggtga ccatggaggt gccgtgcgac agccggggcc    540

aacgcatgtg gtgggctttc ctggcctcct ccatggtgac tttcttcggg ggcctcttca    600

tcatcttgct ctggcggacg ctcaagtacc tgtggaccgt gtgctgccac tgcgggggca    660

agacgaagga ggcccagaag attaacaatg gctcaagcca ggcggatggc actctcaaac    720

cagtggatga aaaagaggag gcagtggccg ccgaggtcgg ctggatgacc tccgtgaagg    780

actgggcggg ggtgatgata tccgcccaga cactgactgg cagagtcctg gttgtcttag    840

tctttgctct cagcatcggt gcacttgtaa tatacttcat agattcatca aacccaatag    900

aatcctgcca gaatttctac aaagatttca cattacagat cgacatggct ttcaacgtgt    960

tcttccttct ctacttcggc ttgcggttta ttgcagccaa cgataaattg tggttctggc   1020

tggaagtgaa ctctgtagtg gatttcttca cggtgccccc cgtgtttgtg tctgtgtact   1080

taaacagaag ttggcttggt ttgagatttt taagagctct gagactgata cagttttcag   1140

aaattttgca gtttctgaat attcttaaaa caagtaattc catcaagctg gtgaatctgc   1200

tctccatatt tatcagcacg tggctgactg cagccgggtt catccatttg gtggagaatt   1260

caggggaccc atgggaaaat ttccaaaaca accaggctct cacctactgg gaatgtgtct   1320

atttactcat ggtcacaatg tccaccgttg gttatgggga tgtttatgca aaaaccacac   1380

ttgggcgcct cttcatggtc ttcttcatcc tcgggggact ggccatgttt gccagctacg   1440

tccctgaaat catagagtta ataggaaacc gcaagaaata cgggggctcc tatagtgcgg   1500

ttagtggaag aaagcacatt gtggtctgcg gacacatcac tctggagagt gtttccaact   1560

tcctgaagga ctttctgcac aaggaccggg atgacgtcaa tgtggagatc gtttttcttc   1620

acaacatctc ccccaacctg gagcttgaag ctctgttcaa acgacatttt actcaggtgg   1680

aattttatca gggttccgtc ctcaatccac atgatcttgc aagagtcaag atagagtcag   1740

cagatgcatg cctgatcctt gccaacaagt actgcgctga cccggatgcg gaggatgcct   1800

cgaatatcat gagagtaatc tccataaaga actaccatcc gaagataaga atcatcactc   1860

aaatgctgca gtatcacaac aaggcccatc tgctaaacat cccgagctgg aattggaaag   1920

aaggtgatga cgcaatctgc ctcgcagagt tgaagttggg cttcatagcc cagagctgcc   1980

tggctcaagg cctctccacc atgcttgcca acctcttctc catgaggtca ttcataaaga   2040

ttgaggaaga cacatggcag aaatactact tggaaggagt ctcaaatgaa atgtacacag   2100

aatatctctc cagtgccttc gtgggtctgt ccttccctac tgtttgtgag ctgtgttttg   2160

tgaagctcaa gctcctaatg atagccattg agtacaagtc tgccaaccga gagagccgta   2220

tattaattaa tcctggaaac catcttaaga tccaagaagg tactttagga tttttcatcg   2280

caagtgatgc caaagaagtt aaaagggcat ttttttactg caaggcctgt catgatgaca   2340

tcacagatcc caaaagaata aaaaaatgtg gctgcaaacg gcccaagatg tccatctaca   2400

agagaatgag acgggcatgt tgttttgatt gcggacgttc tgagcgtgac tgctcatgca   2460

tgtcaggccg tgtgcgtggt aacgtggaca cccttgagag agccttccca ctttcttctg   2520

tctctgttaa tgattgctcc accagtttcc gtgcctttga agatgagcag ccgtcaacac   2580

tatcaccaaa aaaaaagcaa cggaatggag gcatgcggaa ctcacccaac acctcgccta   2640

agctgatgag gcatgacccc ttgttaattc ctggcaatga tcagattgac aacatggact   2700

ccaatgtgaa gaagtacgac tctactggga tgtttcactg gtgtgcaccc aaggagatag   2760

agaaagtcat cctgactcga agtgaagctg ccatgaccgt cctgagtggc catgtcgtgg   2820

tctgcatctt tggcgacgtc agctcagccc tgatcggcct ccggaacctg gtgatgccgc   2880

tccgtgccag caactttcat taccatgagc tcaagcacat tgtgtttgtg ggctctattg   2940

agtacctcaa gcgggaatgg gagacgcttc ataacttccc caaagtgtcc atattgcctg   3000

gtacgccatt aagtcgggct gatttaaggg ctgtcaacat caacctctgt gacatgtgcg   3060

ttatcctgtc agccaatcag aataatattg atgatacttc gctgcaggac aaggaatgca   3120

tcttggcgtc actcaacatc aaatctatgc agtttgatga cagcatcgga gtcttgcagg   3180

ctaattccca agggttcaca cctccaggaa tggatagatc ctctccagat aacagcccag   3240

tgcacgggat gttacgtcaa ccatccatca caactggggt caacatcccc atcatcactg   3300

aactagtgaa cgatactaat gttcagtttt tggaccaaga cgatgatgat gaccctgata   3360

cagaactgta cctcacgcag ccctttgcct gtgggacagc atttgccgtc agtgtcctgg   3420

actcactcat gagcgcgacg tacttcaatg acaatatcct caccctgata cggaccctgg   3480

tgaccggagg agccacgccg gagctggagg ctctgattgc tgaggaaaac gcccttagag   3540

gtggctacag caccccgcag acactggcca atagggaccg ctgccgcgtg gcccagttag   3600

ctctgctcga tgggccattt gcggacttag gggatggtgg ttgttatggt gatctgttct   3660

gcaaagctct gaaaacatat aatatgcttt gttttggaat ttaccggctg agagatgctc   3720

acctcagcac ccccagtcag tgcacaaaga ggtatgtcat caccaacccg ccctatgagt   3780

ttgagctcgt gccgacggac ctgatcttct gcttaatgca gtttgaccac aatgccggcc   3840

agtcccgggc cagcctgtcc cattcctccc actcgtcgca gtcctccagc aagaagagct   3900

cctctgttca ctccatccca tccacagcaa accgacagaa ccggcccaag tccagggagt   3960

cccgggacaa acagaagtac gtgcaggaag agcggctttg atatgtgtat ccaccgccac   4020

tgtgtgaaac tgtatctgcc actcatttcc ccagttggtg tttccaacaa agtaactttc   4080

cctgttttcc cctgtagtcc cccccttttt ttttacacat atttgcatat gtatgatagt   4140

gtgcatgtgg ttgtcatttt tatttcacca ccataaaacc cttgagcaca acagcaaata   4200

agcagacgga ccaaaagtta tttatgattc tgggggaaaa ataacccaaa ggcatgctcc   4260

agacataaat agctcactgc aggaacgagt tcacagatta gaagggagca cttgtgatca   4320

acgtcagtta ggcagagcaa gtttatttaa tgtaaaagaa aagttgattc tgatttatca   4380

ggattatcag ggtgctttgg gttttgattt tgttgttgtt gttgttttcc tttctttctt   4440

tttttataca cacaataagt tagcacatgt ttatttgaaa caagcaacca aacagcaatg   4500

aaaacatatt gattgtttcc agtctctggg ccgaagtatt gcgaagcatt tgaaaagctt   4560

tcacgatttg tgtagatgat tatgaaggac ctgcttgttg caagagaaca tcagtgattt   4620

ttttagttac tcaccaaggc cttttgtccc agagccagtt ccctctggga gttcttatga   4680

acatttctca ccttaatatg gaggagagaa tagtattcca atcatggatg tatcaaattc   4740

tagtcattta gtttaagtga aaagaggttt gattgcatat taaattgtta ttctgtctcc   4800

ttatgttgcc atatgaatag ctattttttt tctttcactt ttgacatttg ggatgaaaag   4860

ccatatgtat cataaatatc agatgtaagt cattaaaaac tgccttcctg ggacttttac   4920

atcttttaaa aggtgaatta cttaccttat gtacagaata aataatgctc aggaaagagc   4980

aagtattttt ccatgcattc tcaggggatc tttttactcc cctttgtttg attagttagg   5040

gccccaatgc caggtaggag gaagggctgg ggcaatggta gagtgagagg aagacaaacc   5100

cagctgcaga tcatgctttt ctaggagccg acatgctaaa taaattagaa tgtaggagga   5160

tcagccacag ttgactcaac aaagacaaaa gccagccacc accttcaact gttggcacag   5220

ctgtgcggtg ctggctgtcc caatgcagaa agctggtggg aaggaattcc tcatcatcac   5280

tttctttaat gtagccaatt taggcagggt aatgacggca atagagagct gctccttgtc   5340

attatgagac gtgggataag aagagtgcaa cagtgagcca aacacatttt ggtatagtta   5400

tttttttctt cttttgtttt ctttcttttt taacacttag taagcatgag aggagaggta   5460

gaaaaatacc cttttttcaa catatagttg tcagatgctt tgtgcatgca aatcatgctt   5520

taggcagtgc ggtatttctt aaaaactggc caattcacca taaccaattt cccttatgga   5580

tggactaggc tggtatatac atatttgaaa agttttactt caaagaattc catcgaatag   5640

aataggggta aaagggagga ggaaaacatg tcacagctgt accatctcta aaaaggtgtt   5700

tttatggtga atgttttgga tttagatttt ggatcccccg tcccctcaag catgatagtt   5760

ttggatattt gcttgctgtg tgaattgaca agcactttta ctgacaaatg gtgaggctca   5820

gtcagaacct ccaccctccc ccacaccaaa gacaggggca gcgtagtatt caaaccagta   5880

ttgtggtggg gaataattgt atacatgtaa attatcaagc cctatgagtg gaagaatttt   5940

ttcaaattat ttttgtccct ctatatattg atttatatta tgtataacta tctctttata   6000

taaactatat ataattatat atatataact atataattat atatatataa ctatatatat   6060

aactatatat atgtatcccc tagtattgga tcatgaagag ctcttcatgc attctttgca   6120

aaggaggtta taaagttacg ccctcagaac atttataact ataagaatgt gccagttaaa   6180

gtgctcaaca ggaaatatga cagtttaaaa gcattgtaaa actcacatag cttacttctc   6240

tctctaaagt gcaacaagga tgaatagaat gggccaaggt atgacaatta atggttctgc   6300

atgacctagc cactgctggg ggttttcttc tataacgttg tccttgtgaa aacttttgtg   6360

aaattaaaaa aaaaggagtt acaaatttta ttctgtt                            6397


<210>  7114
<211>  1236
<212>  PRT
<213>  Homo sapiens

<400>  7114

Met Ala Asn Gly Gly Gly Gly Gly Gly Gly Ser Ser Gly Gly Gly Gly 
1               5                   10                  15


Gly Gly Gly Gly Ser Ser Leu Arg Met Ser Ser Asn Ile His Ala Asn 
            20                  25                  30


His Leu Ser Leu Asp Ala Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
        35                  40                  45


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Val His Glu Pro 
    50                  55                  60


Lys Met Asp Ala Leu Ile Ile Pro Val Thr Met Glu Val Pro Cys Asp 
65                  70                  75                  80


Ser Arg Gly Gln Arg Met Trp Trp Ala Phe Leu Ala Ser Ser Met Val 
                85                  90                  95


Thr Phe Phe Gly Gly Leu Phe Ile Ile Leu Leu Trp Arg Thr Leu Lys 
            100                 105                 110


Tyr Leu Trp Thr Val Cys Cys His Cys Gly Gly Lys Thr Lys Glu Ala 
        115                 120                 125


Gln Lys Ile Asn Asn Gly Ser Ser Gln Ala Asp Gly Thr Leu Lys Pro 
    130                 135                 140


Val Asp Glu Lys Glu Glu Ala Val Ala Ala Glu Val Gly Trp Met Thr 
145                 150                 155                 160


Ser Val Lys Asp Trp Ala Gly Val Met Ile Ser Ala Gln Thr Leu Thr 
                165                 170                 175


Gly Arg Val Leu Val Val Leu Val Phe Ala Leu Ser Ile Gly Ala Leu 
            180                 185                 190


Val Ile Tyr Phe Ile Asp Ser Ser Asn Pro Ile Glu Ser Cys Gln Asn 
        195                 200                 205


Phe Tyr Lys Asp Phe Thr Leu Gln Ile Asp Met Ala Phe Asn Val Phe 
    210                 215                 220


Phe Leu Leu Tyr Phe Gly Leu Arg Phe Ile Ala Ala Asn Asp Lys Leu 
225                 230                 235                 240


Trp Phe Trp Leu Glu Val Asn Ser Val Val Asp Phe Phe Thr Val Pro 
                245                 250                 255


Pro Val Phe Val Ser Val Tyr Leu Asn Arg Ser Trp Leu Gly Leu Arg 
            260                 265                 270


Phe Leu Arg Ala Leu Arg Leu Ile Gln Phe Ser Glu Ile Leu Gln Phe 
        275                 280                 285


Leu Asn Ile Leu Lys Thr Ser Asn Ser Ile Lys Leu Val Asn Leu Leu 
    290                 295                 300


Ser Ile Phe Ile Ser Thr Trp Leu Thr Ala Ala Gly Phe Ile His Leu 
305                 310                 315                 320


Val Glu Asn Ser Gly Asp Pro Trp Glu Asn Phe Gln Asn Asn Gln Ala 
                325                 330                 335


Leu Thr Tyr Trp Glu Cys Val Tyr Leu Leu Met Val Thr Met Ser Thr 
            340                 345                 350


Val Gly Tyr Gly Asp Val Tyr Ala Lys Thr Thr Leu Gly Arg Leu Phe 
        355                 360                 365


Met Val Phe Phe Ile Leu Gly Gly Leu Ala Met Phe Ala Ser Tyr Val 
    370                 375                 380


Pro Glu Ile Ile Glu Leu Ile Gly Asn Arg Lys Lys Tyr Gly Gly Ser 
385                 390                 395                 400


Tyr Ser Ala Val Ser Gly Arg Lys His Ile Val Val Cys Gly His Ile 
                405                 410                 415


Thr Leu Glu Ser Val Ser Asn Phe Leu Lys Asp Phe Leu His Lys Asp 
            420                 425                 430


Arg Asp Asp Val Asn Val Glu Ile Val Phe Leu His Asn Ile Ser Pro 
        435                 440                 445


Asn Leu Glu Leu Glu Ala Leu Phe Lys Arg His Phe Thr Gln Val Glu 
    450                 455                 460


Phe Tyr Gln Gly Ser Val Leu Asn Pro His Asp Leu Ala Arg Val Lys 
465                 470                 475                 480


Ile Glu Ser Ala Asp Ala Cys Leu Ile Leu Ala Asn Lys Tyr Cys Ala 
                485                 490                 495


Asp Pro Asp Ala Glu Asp Ala Ser Asn Ile Met Arg Val Ile Ser Ile 
            500                 505                 510


Lys Asn Tyr His Pro Lys Ile Arg Ile Ile Thr Gln Met Leu Gln Tyr 
        515                 520                 525


His Asn Lys Ala His Leu Leu Asn Ile Pro Ser Trp Asn Trp Lys Glu 
    530                 535                 540


Gly Asp Asp Ala Ile Cys Leu Ala Glu Leu Lys Leu Gly Phe Ile Ala 
545                 550                 555                 560


Gln Ser Cys Leu Ala Gln Gly Leu Ser Thr Met Leu Ala Asn Leu Phe 
                565                 570                 575


Ser Met Arg Ser Phe Ile Lys Ile Glu Glu Asp Thr Trp Gln Lys Tyr 
            580                 585                 590


Tyr Leu Glu Gly Val Ser Asn Glu Met Tyr Thr Glu Tyr Leu Ser Ser 
        595                 600                 605


Ala Phe Val Gly Leu Ser Phe Pro Thr Val Cys Glu Leu Cys Phe Val 
    610                 615                 620


Lys Leu Lys Leu Leu Met Ile Ala Ile Glu Tyr Lys Ser Ala Asn Arg 
625                 630                 635                 640


Glu Ser Arg Ile Leu Ile Asn Pro Gly Asn His Leu Lys Ile Gln Glu 
                645                 650                 655


Gly Thr Leu Gly Phe Phe Ile Ala Ser Asp Ala Lys Glu Val Lys Arg 
            660                 665                 670


Ala Phe Phe Tyr Cys Lys Ala Cys His Asp Asp Ile Thr Asp Pro Lys 
        675                 680                 685


Arg Ile Lys Lys Cys Gly Cys Lys Arg Pro Lys Met Ser Ile Tyr Lys 
    690                 695                 700


Arg Met Arg Arg Ala Cys Cys Phe Asp Cys Gly Arg Ser Glu Arg Asp 
705                 710                 715                 720


Cys Ser Cys Met Ser Gly Arg Val Arg Gly Asn Val Asp Thr Leu Glu 
                725                 730                 735


Arg Ala Phe Pro Leu Ser Ser Val Ser Val Asn Asp Cys Ser Thr Ser 
            740                 745                 750


Phe Arg Ala Phe Glu Asp Glu Gln Pro Ser Thr Leu Ser Pro Lys Lys 
        755                 760                 765


Lys Gln Arg Asn Gly Gly Met Arg Asn Ser Pro Asn Thr Ser Pro Lys 
    770                 775                 780


Leu Met Arg His Asp Pro Leu Leu Ile Pro Gly Asn Asp Gln Ile Asp 
785                 790                 795                 800


Asn Met Asp Ser Asn Val Lys Lys Tyr Asp Ser Thr Gly Met Phe His 
                805                 810                 815


Trp Cys Ala Pro Lys Glu Ile Glu Lys Val Ile Leu Thr Arg Ser Glu 
            820                 825                 830


Ala Ala Met Thr Val Leu Ser Gly His Val Val Val Cys Ile Phe Gly 
        835                 840                 845


Asp Val Ser Ser Ala Leu Ile Gly Leu Arg Asn Leu Val Met Pro Leu 
    850                 855                 860


Arg Ala Ser Asn Phe His Tyr His Glu Leu Lys His Ile Val Phe Val 
865                 870                 875                 880


Gly Ser Ile Glu Tyr Leu Lys Arg Glu Trp Glu Thr Leu His Asn Phe 
                885                 890                 895


Pro Lys Val Ser Ile Leu Pro Gly Thr Pro Leu Ser Arg Ala Asp Leu 
            900                 905                 910


Arg Ala Val Asn Ile Asn Leu Cys Asp Met Cys Val Ile Leu Ser Ala 
        915                 920                 925


Asn Gln Asn Asn Ile Asp Asp Thr Ser Leu Gln Asp Lys Glu Cys Ile 
    930                 935                 940


Leu Ala Ser Leu Asn Ile Lys Ser Met Gln Phe Asp Asp Ser Ile Gly 
945                 950                 955                 960


Val Leu Gln Ala Asn Ser Gln Gly Phe Thr Pro Pro Gly Met Asp Arg 
                965                 970                 975


Ser Ser Pro Asp Asn Ser Pro Val His Gly Met Leu Arg Gln Pro Ser 
            980                 985                 990


Ile Thr Thr Gly Val Asn Ile Pro Ile Ile Thr Glu Leu Val Asn Asp 
        995                 1000                1005


Thr Asn Val Gln Phe Leu Asp Gln Asp Asp Asp Asp Asp Pro Asp Thr 
    1010                1015                1020


Glu Leu Tyr Leu Thr Gln Pro Phe Ala Cys Gly Thr Ala Phe Ala Val 
1025                1030                1035                1040


Ser Val Leu Asp Ser Leu Met Ser Ala Thr Tyr Phe Asn Asp Asn Ile 
                1045                1050                1055


Leu Thr Leu Ile Arg Thr Leu Val Thr Gly Gly Ala Thr Pro Glu Leu 
            1060                1065                1070


Glu Ala Leu Ile Ala Glu Glu Asn Ala Leu Arg Gly Gly Tyr Ser Thr 
        1075                1080                1085


Pro Gln Thr Leu Ala Asn Arg Asp Arg Cys Arg Val Ala Gln Leu Ala 
    1090                1095                1100


Leu Leu Asp Gly Pro Phe Ala Asp Leu Gly Asp Gly Gly Cys Tyr Gly 
1105                1110                1115                1120


Asp Leu Phe Cys Lys Ala Leu Lys Thr Tyr Asn Met Leu Cys Phe Gly 
                1125                1130                1135


Ile Tyr Arg Leu Arg Asp Ala His Leu Ser Thr Pro Ser Gln Cys Thr 
            1140                1145                1150


Lys Arg Tyr Val Ile Thr Asn Pro Pro Tyr Glu Phe Glu Leu Val Pro 
        1155                1160                1165


Thr Asp Leu Ile Phe Cys Leu Met Gln Phe Asp His Asn Ala Gly Gln 
    1170                1175                1180


Ser Arg Ala Ser Leu Ser His Ser Ser His Ser Ser Gln Ser Ser Ser 
1185                1190                1195                1200


Lys Lys Ser Ser Ser Val His Ser Ile Pro Ser Thr Ala Asn Arg Gln 
                1205                1210                1215


Asn Arg Pro Lys Ser Arg Glu Ser Arg Asp Lys Gln Lys Tyr Val Gln 
            1220                1225                1230


Glu Glu Arg Leu 
        1235


<210>  7115
<211>  6346
<212>  DNA
<213>  Homo sapiens

<400>  7115
cgcagcccgg ggcgagcggg gcgcgggccg gggaggggga gctgcccgcg cactccatcc     60

ccctcccccc cgggcgggcg gcggcggctc gctgtatata tctcggcgca ccccgccagg    120

tcgcgcacag cgccccgagc ccaggcgcct ccccgccccc ctcccgcgct ccgcggcggc    180

ggcggcggcg gcagcagtag cagcaatatg gctgttgatg ggtgtttggg gtggcgctgg    240

cggcgggagg agctcccccg agcccctgcg ccggctgccc gttgctagct atggcaaatg    300

gtggcggcgg cggcggcggc agcagcggcg gcggcggcgg cggcggaggc agcagtctta    360

gaatgagtag caatatccac gcgaaccatc tcagcctaga cgcgtcctcc tcctcctcct    420

cctcctcttc ctcttcttct tcttcctcct cctcttcctc ctcgtcctcg gtccacgagc    480

ccaagatgga tgcgctcatc atcccggtga ccatggaggt gccgtgcgac agccggggcc    540

aacgcatgtg gtgggctttc ctggcctcct ccatggtgac tttcttcggg ggcctcttca    600

tcatcttgct ctggcggacg ctcaagtacc tgtggaccgt gtgctgccac tgcgggggca    660

agacgaagga ggcccagaag attaacaatg gctcaagcca ggcggatggc actctcaaac    720

cagtggatga aaaagaggag gcagtggccg ccgaggtcgg ctggatgacc tccgtgaagg    780

actgggcggg ggtgatgata tccgcccaga cactgactgg cagagtcctg gttgtcttag    840

tctttgctct cagcatcggt gcacttgtaa tatacttcat agattcatca aacccaatag    900

aatcctgcca gaatttctac aaagatttca cattacagat cgacatggct ttcaacgtgt    960

tcttccttct ctacttcggc ttgcggttta ttgcagccaa cgataaattg tggttctggc   1020

tggaagtgaa ctctgtagtg gatttcttca cggtgccccc cgtgtttgtg tctgtgtact   1080

taaacagaag ttggcttggt ttgagatttt taagagctct gagactgata cagttttcag   1140

aaattttgca gtttctgaat attcttaaaa caagtaattc catcaagctg gtgaatctgc   1200

tctccatatt tatcagcacg tggctgactg cagccgggtt catccatttg gtggagaatt   1260

caggggaccc atgggaaaat ttccaaaaca accaggctct cacctactgg gaatgtgtct   1320

atttactcat ggtcacaatg tccaccgttg gttatgggga tgtttatgca aaaaccacac   1380

ttgggcgcct cttcatggtc ttcttcatcc tcgggggact ggccatgttt gccagctacg   1440

tccctgaaat catagagtta ataggaaacc gcaagaaata cgggggctcc tatagtgcgg   1500

ttagtggaag aaagcacatt gtggtctgcg gacacatcac tctggagagt gtttccaact   1560

tcctgaagga ctttctgcac aaggaccggg atgacgtcaa tgtggagatc gtttttcttc   1620

acaacatctc ccccaacctg gagcttgaag ctctgttcaa acgacatttt actcaggtgg   1680

aattttatca gggttccgtc ctcaatccac atgatcttgc aagagtcaag atagagtcag   1740

cagatgcatg cctgatcctt gccaacaagt actgcgctga cccggatgcg gaggatgcct   1800

cgaatatcat gagagtaatc tccataaaga actaccatcc gaagataaga atcatcactc   1860

aaatgctgca gtatcacaac aaggcccatc tgctaaacat cccgagctgg aattggaaag   1920

aaggtgatga cgcaatctgc ctcgcagagt tgaagttggg cttcatagcc cagagctgcc   1980

tggctcaagg cctctccacc atgcttgcca acctcttctc catgaggtca ttcataaaga   2040

ttgaggaaga cacatggcag aaatactact tggaaggagt ctcaaatgaa atgtacacag   2100

aatatctctc cagtgccttc gtgggtctgt ccttccctac tgtttgtgag ctgtgttttg   2160

tgaagctcaa gctcctaatg atagccattg agtacaagtc tgccaaccga gagagccgta   2220

tattaattaa tcctggaaac catcttaaga tccaagaagg tactttagga tttttcatcg   2280

caagtgatgc caaagaagtt aaaagggcat ttttttactg caaggcctgt catgatgaca   2340

tcacagatcc caaaagaata aaaaaatgtg gctgcaaacg gcttgaagat gagcagccgt   2400

caacactatc accaaaaaaa aagcaacgga atggaggcat gcggaactca cccaacacct   2460

cgcctaagct gatgaggcat gaccccttgt taattcctgg caatgatcag attgacaaca   2520

tggactccaa tgtgaagaag tacgactcta ctgggatgtt tcactggtgt gcacccaagg   2580

agatagagaa agtcatcctg gtcacaggct ggatgccgta tctgggacct agggttttaa   2640

tgacttgcct ggatattggt gtagtatgca tgccaactga tattcaatca acatctcctg   2700

ccagcataaa aaagtttaag gagactcgaa gtgaagctgc catgaccgtc ctgagtggcc   2760

atgtcgtggt ctgcatcttt ggcgacgtca gctcagccct gatcggcctc cggaacctgg   2820

tgatgccgct ccgtgccagc aactttcatt accatgagct caagcacatt gtgtttgtgg   2880

gctctattga gtacctcaag cgggaatggg agacgcttca taacttcccc aaagtgtcca   2940

tattgcctgg tacgccatta agtcgggctg atttaagggc tgtcaacatc aacctctgtg   3000

acatgtgcgt tatcctgtca gccaatcaga ataatattga tgatacttcg ctgcaggaca   3060

aggaatgcat cttggcgtca ctcaacatca aatctatgca gtttgatgac agcatcggag   3120

tcttgcaggc taattcccaa gggttcacac ctccaggaat ggatagatcc tctccagata   3180

acagcccagt gcacgggatg ttacgtcaac catccatcac aactggggtc aacatcccca   3240

tcatcactga actagtgaac gatactaatg ttcagttttt ggaccaagac gatgatgatg   3300

accctgatac agaactgtac ctcacgcagc cctttgcctg tgggacagca tttgccgtca   3360

gtgtcctgga ctcactcatg agcgcgacgt acttcaatga caatatcctc accctgatac   3420

ggaccctggt gaccggagga gccacgccgg agctggaggc tctgattgct gaggaaaacg   3480

cccttagagg tggctacagc accccgcaga cactggccaa tagggaccgc tgccgcgtgg   3540

cccagttagc tctgctcgat gggccatttg cggacttagg ggatggtggt tgttatggtg   3600

atctgttctg caaagctctg aaaacatata atatgctttg ttttggaatt taccggctga   3660

gagatgctca cctcagcacc cccagtcagt gcacaaagag gtatgtcatc accaacccgc   3720

cctatgagtt tgagctcgtg ccgacggacc tgatcttctg cttaatgcag tttgaccaca   3780

atgccggcca gtcccgggcc agcctgtccc attcctccca ctcgtcgcag tcctccagca   3840

agaagagctc ctctgttcac tccatcccat ccacagcaaa ccgacagaac cggcccaagt   3900

ccagggagtc ccgggacaaa cagaagtacg tgcaggaaga gcggctttga tatgtgtatc   3960

caccgccact gtgtgaaact gtatctgcca ctcatttccc cagttggtgt ttccaacaaa   4020

gtaactttcc ctgttttccc ctgtagtccc cccctttttt tttacacata tttgcatatg   4080

tatgatagtg tgcatgtggt tgtcattttt atttcaccac cataaaaccc ttgagcacaa   4140

cagcaaataa gcagacggac caaaagttat ttatgattct gggggaaaaa taacccaaag   4200

gcatgctcca gacataaata gctcactgca ggaacgagtt cacagattag aagggagcac   4260

ttgtgatcaa cgtcagttag gcagagcaag tttatttaat gtaaaagaaa agttgattct   4320

gatttatcag gattatcagg gtgctttggg ttttgatttt gttgttgttg ttgttttcct   4380

ttctttcttt ttttatacac acaataagtt agcacatgtt tatttgaaac aagcaaccaa   4440

acagcaatga aaacatattg attgtttcca gtctctgggc cgaagtattg cgaagcattt   4500

gaaaagcttt cacgatttgt gtagatgatt atgaaggacc tgcttgttgc aagagaacat   4560

cagtgatttt tttagttact caccaaggcc ttttgtccca gagccagttc cctctgggag   4620

ttcttatgaa catttctcac cttaatatgg aggagagaat agtattccaa tcatggatgt   4680

atcaaattct agtcatttag tttaagtgaa aagaggtttg attgcatatt aaattgttat   4740

tctgtctcct tatgttgcca tatgaatagc tatttttttt ctttcacttt tgacatttgg   4800

gatgaaaagc catatgtatc ataaatatca gatgtaagtc attaaaaact gccttcctgg   4860

gacttttaca tcttttaaaa ggtgaattac ttaccttatg tacagaataa ataatgctca   4920

ggaaagagca agtatttttc catgcattct caggggatct ttttactccc ctttgtttga   4980

ttagttaggg ccccaatgcc aggtaggagg aagggctggg gcaatggtag agtgagagga   5040

agacaaaccc agctgcagat catgcttttc taggagccga catgctaaat aaattagaat   5100

gtaggaggat cagccacagt tgactcaaca aagacaaaag ccagccacca ccttcaactg   5160

ttggcacagc tgtgcggtgc tggctgtccc aatgcagaaa gctggtggga aggaattcct   5220

catcatcact ttctttaatg tagccaattt aggcagggta atgacggcaa tagagagctg   5280

ctccttgtca ttatgagacg tgggataaga agagtgcaac agtgagccaa acacattttg   5340

gtatagttat ttttttcttc ttttgttttc tttctttttt aacacttagt aagcatgaga   5400

ggagaggtag aaaaataccc ttttttcaac atatagttgt cagatgcttt gtgcatgcaa   5460

atcatgcttt aggcagtgcg gtatttctta aaaactggcc aattcaccat aaccaatttc   5520

ccttatggat ggactaggct ggtatataca tatttgaaaa gttttacttc aaagaattcc   5580

atcgaataga ataggggtaa aagggaggag gaaaacatgt cacagctgta ccatctctaa   5640

aaaggtgttt ttatggtgaa tgttttggat ttagattttg gatcccccgt cccctcaagc   5700

atgatagttt tggatatttg cttgctgtgt gaattgacaa gcacttttac tgacaaatgg   5760

tgaggctcag tcagaacctc caccctcccc cacaccaaag acaggggcag cgtagtattc   5820

aaaccagtat tgtggtgggg aataattgta tacatgtaaa ttatcaagcc ctatgagtgg   5880

aagaattttt tcaaattatt tttgtccctc tatatattga tttatattat gtataactat   5940

ctctttatat aaactatata taattatata tatataacta tataattata tatatataac   6000

tatatatata actatatata tgtatcccct agtattggat catgaagagc tcttcatgca   6060

ttctttgcaa aggaggttat aaagttacgc cctcagaaca tttataacta taagaatgtg   6120

ccagttaaag tgctcaacag gaaatatgac agtttaaaag cattgtaaaa ctcacatagc   6180

ttacttctct ctctaaagtg caacaaggat gaatagaatg ggccaaggta tgacaattaa   6240

tggttctgca tgacctagcc actgctgggg gttttcttct ataacgttgt ccttgtgaaa   6300

acttttgtga aattaaaaaa aaaggagtta caaattttat tctgtt                  6346


<210>  7116
<211>  1219
<212>  PRT
<213>  Homo sapiens

<400>  7116

Met Ala Asn Gly Gly Gly Gly Gly Gly Gly Ser Ser Gly Gly Gly Gly 
1               5                   10                  15


Gly Gly Gly Gly Ser Ser Leu Arg Met Ser Ser Asn Ile His Ala Asn 
            20                  25                  30


His Leu Ser Leu Asp Ala Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
        35                  40                  45


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Val His Glu Pro 
    50                  55                  60


Lys Met Asp Ala Leu Ile Ile Pro Val Thr Met Glu Val Pro Cys Asp 
65                  70                  75                  80


Ser Arg Gly Gln Arg Met Trp Trp Ala Phe Leu Ala Ser Ser Met Val 
                85                  90                  95


Thr Phe Phe Gly Gly Leu Phe Ile Ile Leu Leu Trp Arg Thr Leu Lys 
            100                 105                 110


Tyr Leu Trp Thr Val Cys Cys His Cys Gly Gly Lys Thr Lys Glu Ala 
        115                 120                 125


Gln Lys Ile Asn Asn Gly Ser Ser Gln Ala Asp Gly Thr Leu Lys Pro 
    130                 135                 140


Val Asp Glu Lys Glu Glu Ala Val Ala Ala Glu Val Gly Trp Met Thr 
145                 150                 155                 160


Ser Val Lys Asp Trp Ala Gly Val Met Ile Ser Ala Gln Thr Leu Thr 
                165                 170                 175


Gly Arg Val Leu Val Val Leu Val Phe Ala Leu Ser Ile Gly Ala Leu 
            180                 185                 190


Val Ile Tyr Phe Ile Asp Ser Ser Asn Pro Ile Glu Ser Cys Gln Asn 
        195                 200                 205


Phe Tyr Lys Asp Phe Thr Leu Gln Ile Asp Met Ala Phe Asn Val Phe 
    210                 215                 220


Phe Leu Leu Tyr Phe Gly Leu Arg Phe Ile Ala Ala Asn Asp Lys Leu 
225                 230                 235                 240


Trp Phe Trp Leu Glu Val Asn Ser Val Val Asp Phe Phe Thr Val Pro 
                245                 250                 255


Pro Val Phe Val Ser Val Tyr Leu Asn Arg Ser Trp Leu Gly Leu Arg 
            260                 265                 270


Phe Leu Arg Ala Leu Arg Leu Ile Gln Phe Ser Glu Ile Leu Gln Phe 
        275                 280                 285


Leu Asn Ile Leu Lys Thr Ser Asn Ser Ile Lys Leu Val Asn Leu Leu 
    290                 295                 300


Ser Ile Phe Ile Ser Thr Trp Leu Thr Ala Ala Gly Phe Ile His Leu 
305                 310                 315                 320


Val Glu Asn Ser Gly Asp Pro Trp Glu Asn Phe Gln Asn Asn Gln Ala 
                325                 330                 335


Leu Thr Tyr Trp Glu Cys Val Tyr Leu Leu Met Val Thr Met Ser Thr 
            340                 345                 350


Val Gly Tyr Gly Asp Val Tyr Ala Lys Thr Thr Leu Gly Arg Leu Phe 
        355                 360                 365


Met Val Phe Phe Ile Leu Gly Gly Leu Ala Met Phe Ala Ser Tyr Val 
    370                 375                 380


Pro Glu Ile Ile Glu Leu Ile Gly Asn Arg Lys Lys Tyr Gly Gly Ser 
385                 390                 395                 400


Tyr Ser Ala Val Ser Gly Arg Lys His Ile Val Val Cys Gly His Ile 
                405                 410                 415


Thr Leu Glu Ser Val Ser Asn Phe Leu Lys Asp Phe Leu His Lys Asp 
            420                 425                 430


Arg Asp Asp Val Asn Val Glu Ile Val Phe Leu His Asn Ile Ser Pro 
        435                 440                 445


Asn Leu Glu Leu Glu Ala Leu Phe Lys Arg His Phe Thr Gln Val Glu 
    450                 455                 460


Phe Tyr Gln Gly Ser Val Leu Asn Pro His Asp Leu Ala Arg Val Lys 
465                 470                 475                 480


Ile Glu Ser Ala Asp Ala Cys Leu Ile Leu Ala Asn Lys Tyr Cys Ala 
                485                 490                 495


Asp Pro Asp Ala Glu Asp Ala Ser Asn Ile Met Arg Val Ile Ser Ile 
            500                 505                 510


Lys Asn Tyr His Pro Lys Ile Arg Ile Ile Thr Gln Met Leu Gln Tyr 
        515                 520                 525


His Asn Lys Ala His Leu Leu Asn Ile Pro Ser Trp Asn Trp Lys Glu 
    530                 535                 540


Gly Asp Asp Ala Ile Cys Leu Ala Glu Leu Lys Leu Gly Phe Ile Ala 
545                 550                 555                 560


Gln Ser Cys Leu Ala Gln Gly Leu Ser Thr Met Leu Ala Asn Leu Phe 
                565                 570                 575


Ser Met Arg Ser Phe Ile Lys Ile Glu Glu Asp Thr Trp Gln Lys Tyr 
            580                 585                 590


Tyr Leu Glu Gly Val Ser Asn Glu Met Tyr Thr Glu Tyr Leu Ser Ser 
        595                 600                 605


Ala Phe Val Gly Leu Ser Phe Pro Thr Val Cys Glu Leu Cys Phe Val 
    610                 615                 620


Lys Leu Lys Leu Leu Met Ile Ala Ile Glu Tyr Lys Ser Ala Asn Arg 
625                 630                 635                 640


Glu Ser Arg Ile Leu Ile Asn Pro Gly Asn His Leu Lys Ile Gln Glu 
                645                 650                 655


Gly Thr Leu Gly Phe Phe Ile Ala Ser Asp Ala Lys Glu Val Lys Arg 
            660                 665                 670


Ala Phe Phe Tyr Cys Lys Ala Cys His Asp Asp Ile Thr Asp Pro Lys 
        675                 680                 685


Arg Ile Lys Lys Cys Gly Cys Lys Arg Leu Glu Asp Glu Gln Pro Ser 
    690                 695                 700


Thr Leu Ser Pro Lys Lys Lys Gln Arg Asn Gly Gly Met Arg Asn Ser 
705                 710                 715                 720


Pro Asn Thr Ser Pro Lys Leu Met Arg His Asp Pro Leu Leu Ile Pro 
                725                 730                 735


Gly Asn Asp Gln Ile Asp Asn Met Asp Ser Asn Val Lys Lys Tyr Asp 
            740                 745                 750


Ser Thr Gly Met Phe His Trp Cys Ala Pro Lys Glu Ile Glu Lys Val 
        755                 760                 765


Ile Leu Val Thr Gly Trp Met Pro Tyr Leu Gly Pro Arg Val Leu Met 
    770                 775                 780


Thr Cys Leu Asp Ile Gly Val Val Cys Met Pro Thr Asp Ile Gln Ser 
785                 790                 795                 800


Thr Ser Pro Ala Ser Ile Lys Lys Phe Lys Glu Thr Arg Ser Glu Ala 
                805                 810                 815


Ala Met Thr Val Leu Ser Gly His Val Val Val Cys Ile Phe Gly Asp 
            820                 825                 830


Val Ser Ser Ala Leu Ile Gly Leu Arg Asn Leu Val Met Pro Leu Arg 
        835                 840                 845


Ala Ser Asn Phe His Tyr His Glu Leu Lys His Ile Val Phe Val Gly 
    850                 855                 860


Ser Ile Glu Tyr Leu Lys Arg Glu Trp Glu Thr Leu His Asn Phe Pro 
865                 870                 875                 880


Lys Val Ser Ile Leu Pro Gly Thr Pro Leu Ser Arg Ala Asp Leu Arg 
                885                 890                 895


Ala Val Asn Ile Asn Leu Cys Asp Met Cys Val Ile Leu Ser Ala Asn 
            900                 905                 910


Gln Asn Asn Ile Asp Asp Thr Ser Leu Gln Asp Lys Glu Cys Ile Leu 
        915                 920                 925


Ala Ser Leu Asn Ile Lys Ser Met Gln Phe Asp Asp Ser Ile Gly Val 
    930                 935                 940


Leu Gln Ala Asn Ser Gln Gly Phe Thr Pro Pro Gly Met Asp Arg Ser 
945                 950                 955                 960


Ser Pro Asp Asn Ser Pro Val His Gly Met Leu Arg Gln Pro Ser Ile 
                965                 970                 975


Thr Thr Gly Val Asn Ile Pro Ile Ile Thr Glu Leu Val Asn Asp Thr 
            980                 985                 990


Asn Val Gln Phe Leu Asp Gln Asp Asp Asp Asp Asp Pro Asp Thr Glu 
        995                 1000                1005


Leu Tyr Leu Thr Gln Pro Phe Ala Cys Gly Thr Ala Phe Ala Val Ser 
    1010                1015                1020


Val Leu Asp Ser Leu Met Ser Ala Thr Tyr Phe Asn Asp Asn Ile Leu 
1025                1030                1035                1040


Thr Leu Ile Arg Thr Leu Val Thr Gly Gly Ala Thr Pro Glu Leu Glu 
                1045                1050                1055


Ala Leu Ile Ala Glu Glu Asn Ala Leu Arg Gly Gly Tyr Ser Thr Pro 
            1060                1065                1070


Gln Thr Leu Ala Asn Arg Asp Arg Cys Arg Val Ala Gln Leu Ala Leu 
        1075                1080                1085


Leu Asp Gly Pro Phe Ala Asp Leu Gly Asp Gly Gly Cys Tyr Gly Asp 
    1090                1095                1100


Leu Phe Cys Lys Ala Leu Lys Thr Tyr Asn Met Leu Cys Phe Gly Ile 
1105                1110                1115                1120


Tyr Arg Leu Arg Asp Ala His Leu Ser Thr Pro Ser Gln Cys Thr Lys 
                1125                1130                1135


Arg Tyr Val Ile Thr Asn Pro Pro Tyr Glu Phe Glu Leu Val Pro Thr 
            1140                1145                1150


Asp Leu Ile Phe Cys Leu Met Gln Phe Asp His Asn Ala Gly Gln Ser 
        1155                1160                1165


Arg Ala Ser Leu Ser His Ser Ser His Ser Ser Gln Ser Ser Ser Lys 
    1170                1175                1180


Lys Ser Ser Ser Val His Ser Ile Pro Ser Thr Ala Asn Arg Gln Asn 
1185                1190                1195                1200


Arg Pro Lys Ser Arg Glu Ser Arg Asp Lys Gln Lys Tyr Val Gln Glu 
                1205                1210                1215


Glu Arg Leu 



<210>  7117
<211>  6894
<212>  DNA
<213>  Homo sapiens

<400>  7117
ggcgcttgcc gggccgctgc cgaggggccc tgcccacccc tgcccagccc ggagcccagg     60

cgagccagcg cggcgagcct cctcccctcc cgcctgggtc gtcctgagtc cgcgcccgct    120

ccagttgctg cagctgctgc tgctggcggc tgcggggagc gcggggcgcg cgccgaagag    180

gcttgggcgg cgaggacggg gacgaggagg agtcggaggc ggcaaggagg aagagcgagc    240

ggaggccgag gggctcagcg gcgtggcgac aggactaggg ggtcccgaga acatgggcta    300

gcaggcggcc acgggccggc ggccggacgc ggtgaacctg ccgcggccgg gcgcgcactg    360

gcgcggcgag ccggagccga gcgcagccgg gggaggaggg ctggcgcagg ggcgcccggg    420

cggagggggc cgattatcca ttattaacga gttaccacct aataagcgga gagcggctcg    480

ttagccgcgc gggaggcgct cggggaaggg ggtcaccggc cgagcgcagc gcacacccgt    540

ggcgcacggc gggcggcgcg gcgccgagga cacccgggac cgcgcgcgga gccggggcgg    600

gcccgggggc ggcgcagacc ccgggcgcgg gcggcccgcg gcgccccctg gctctcggcg    660

ctcggggcca gcgcagcccg gggcgagcgg ggcgcgggcc ggggaggggg agctgcccgc    720

gcactccatc cccctccccc ccgggcgggc ggcggcggct cgctgtatat atctcggcgc    780

accccgccag gtcgcgcaca gcgccccgag cccaggcgcc tccccgcccc cctcccgcgc    840

tccgcggcgg cggcggcggc ggcagcagta gcagcaatat ggctgttgat gggtgtttgg    900

ggtggcgctg gcggcgggag gagctccccc gagcccctgc gccggctgcc cgttgctagc    960

tatggcaaat ggtggcggcg gcggcggcgg cagcagcggc ggcggcggcg gcggcggagg   1020

cagcagtctt agaatgagta gcaatatcca cgcgaaccat ctcagcctag acgcgtcctc   1080

ctcctcctcc tcctcctctt cctcttcttc ttcttcctcc tcctcttcct cctcgtcctc   1140

ggtccacgag cccaagatgg atgcgctcat catcccggtg accatggagg tgccgtgcga   1200

cagccggggc caacgcatgt ggtgggcttt cctggcctcc tccatggtga ctttcttcgg   1260

gggcctcttc atcatcttgc tctggcggac gctcaagtac ctgtggaccg tgtgctgcca   1320

ctgcgggggc aagacgaagg aggcccagaa gattaacaat ggctcaagcc aggcggatgg   1380

cactctcaaa ccagtggatg aaaaagagga ggcagtggcc gccgaggtcg gctggatgac   1440

ctccgtgaag gactgggcgg gggtgatgat atccgcccag acactgactg gcagagtcct   1500

ggttgtctta gtctttgctc tcagcatcgg tgcacttgta atatacttca tagattcatc   1560

aaacccaata gaatcctgcc agaatttcta caaagatttc acattacaga tcgacatggc   1620

tttcaacgtg ttcttccttc tctacttcgg cttgcggttt attgcagcca acgataaatt   1680

gtggttctgg ctggaagtga actctgtagt ggatttcttc acggtgcccc ccgtgtttgt   1740

gtctgtgtac ttaaacagaa gttggcttgg tttgagattt ttaagagctc tgagactgat   1800

acagttttca gaaattttgc agtttctgaa tattcttaaa acaagtaatt ccatcaagct   1860

ggtgaatctg ctctccatat ttatcagcac gtggctgact gcagccgggt tcatccattt   1920

ggtggagaat tcaggggacc catgggaaaa tttccaaaac aaccaggctc tcacctactg   1980

ggaatgtgtc tatttactca tggtcacaat gtccaccgtt ggttatgggg atgtttatgc   2040

aaaaaccaca cttgggcgcc tcttcatggt cttcttcatc ctcgggggac tggccatgtt   2100

tgccagctac gtccctgaaa tcatagagtt aataggaaac cgcaagaaat acgggggctc   2160

ctatagtgcg gttagtggaa gaaagcacat tgtggtctgc ggacacatca ctctggagag   2220

tgtttccaac ttcctgaagg actttctgca caaggaccgg gatgacgtca atgtggagat   2280

cgtttttctt cacaacatct cccccaacct ggagcttgaa gctctgttca aacgacattt   2340

tactcaggtg gaattttatc agggttccgt cctcaatcca catgatcttg caagagtcaa   2400

gatagagtca gcagatgcat gcctgatcct tgccaacaag tactgcgctg acccggatgc   2460

ggaggatgcc tcgaatatca tgagagtaat ctccataaag aactaccatc cgaagataag   2520

aatcatcact caaatgctgc agtatcacaa caaggcccat ctgctaaaca tcccgagctg   2580

gaattggaaa gaaggtgatg acgcaatctg cctcgcagag ttgaagttgg gcttcatagc   2640

ccagagctgc ctggctcaag gcctctccac catgcttgcc aacctcttct ccatgaggtc   2700

attcataaag attgaggaag acacatggca gaaatactac ttggaaggag tctcaaatga   2760

aatgtacaca gaatatctct ccagtgcctt cgtgggtctg tccttcccta ctgtttgtga   2820

gctgtgtttt gtgaagctca agctcctaat gatagccatt gagtacaagt ctgccaaccg   2880

agagagccgt atattaatta atcctggaaa ccatcttaag atccaagaag gtactttagg   2940

atttttcatc gcaagtgatg ccaaagaagt taaaagggca tttttttact gcaaggcctg   3000

tcatgatgac atcacagatc ccaaaagaat aaaaaaatgt ggctgcaaac ggcttgaaga   3060

tgagcagccg tcaacactat caccaaaaaa aaagcaacgg aatggaggca tgcggaactc   3120

acccaacacc tcgcctaagc tgatgaggca tgaccccttg ttaattcctg gcaatgatca   3180

gattgacaac atggactcca atgtgaagaa gtacgactct actgggatgt ttcactggtg   3240

tgcacccaag gagatagaga aagtcatcct gactcgaagt gaagctgcca tgaccgtcct   3300

gagtggccat gtcgtggtct gcatctttgg cgacgtcagc tcagccctga tcggcctccg   3360

gaacctggtg atgccgctcc gtgccagcaa ctttcattac catgagctca agcacattgt   3420

gtttgtgggc tctattgagt acctcaagcg ggaatgggag acgcttcata acttccccaa   3480

agtgtccata ttgcctggta cgccattaag tcgggctgat ttaagggctg tcaacatcaa   3540

cctctgtgac atgtgcgtta tcctgtcagc caatcagaat aatattgatg atacttcgct   3600

gcaggacaag gaatgcatct tggcgtcact caacatcaaa tctatgcagt ttgatgacag   3660

catcggagtc ttgcaggcta attcccaagg gttcacacct ccaggaatgg atagatcctc   3720

tccagataac agcccagtgc acgggatgtt acgtcaacca tccatcacaa ctggggtcaa   3780

catccccatc atcactgaac tagtgaacga tactaatgtt cagtttttgg accaagacga   3840

tgatgatgac cctgatacag aactgtacct cacgcagccc tttgcctgtg ggacagcatt   3900

tgccgtcagt gtcctggact cactcatgag cgcgacgtac ttcaatgaca atatcctcac   3960

cctgatacgg accctggtga ccggaggagc cacgccggag ctggaggctc tgattgctga   4020

ggaaaacgcc cttagaggtg gctacagcac cccgcagaca ctggccaata gggaccgctg   4080

ccgcgtggcc cagttagctc tgctcgatgg gccatttgcg gacttagggg atggtggttg   4140

ttatggtgat ctgttctgca aagctctgaa aacatataat atgctttgtt ttggaattta   4200

ccggctgaga gatgctcacc tcagcacccc cagtcagtgc acaaagaggt atgtcatcac   4260

caacccgccc tatgagtttg agctcgtgcc gacggacctg atcttctgct taatgcagtt   4320

tgaccacaat gccggccagt cccgggccag cctgtcccat tcctcccact cgtcgcagtc   4380

ctccagcaag aagagctcct ctgttcactc catcccatcc acagcaaacc gacagaaccg   4440

gcccaagtcc agggagtccc gggacaaaca gaagtacgtg caggaagagc ggctttgata   4500

tgtgtatcca ccgccactgt gtgaaactgt atctgccact catttcccca gttggtgttt   4560

ccaacaaagt aactttccct gttttcccct gtagtccccc cctttttttt tacacatatt   4620

tgcatatgta tgatagtgtg catgtggttg tcatttttat ttcaccacca taaaaccctt   4680

gagcacaaca gcaaataagc agacggacca aaagttattt atgattctgg gggaaaaata   4740

acccaaaggc atgctccaga cataaatagc tcactgcagg aacgagttca cagattagaa   4800

gggagcactt gtgatcaacg tcagttaggc agagcaagtt tatttaatgt aaaagaaaag   4860

ttgattctga tttatcagga ttatcagggt gctttgggtt ttgattttgt tgttgttgtt   4920

gttttccttt ctttcttttt ttatacacac aataagttag cacatgttta tttgaaacaa   4980

gcaaccaaac agcaatgaaa acatattgat tgtttccagt ctctgggccg aagtattgcg   5040

aagcatttga aaagctttca cgatttgtgt agatgattat gaaggacctg cttgttgcaa   5100

gagaacatca gtgatttttt tagttactca ccaaggcctt ttgtcccaga gccagttccc   5160

tctgggagtt cttatgaaca tttctcacct taatatggag gagagaatag tattccaatc   5220

atggatgtat caaattctag tcatttagtt taagtgaaaa gaggtttgat tgcatattaa   5280

attgttattc tgtctcctta tgttgccata tgaatagcta ttttttttct ttcacttttg   5340

acatttggga tgaaaagcca tatgtatcat aaatatcaga tgtaagtcat taaaaactgc   5400

cttcctggga cttttacatc ttttaaaagg tgaattactt accttatgta cagaataaat   5460

aatgctcagg aaagagcaag tatttttcca tgcattctca ggggatcttt ttactcccct   5520

ttgtttgatt agttagggcc ccaatgccag gtaggaggaa gggctggggc aatggtagag   5580

tgagaggaag acaaacccag ctgcagatca tgcttttcta ggagccgaca tgctaaataa   5640

attagaatgt aggaggatca gccacagttg actcaacaaa gacaaaagcc agccaccacc   5700

ttcaactgtt ggcacagctg tgcggtgctg gctgtcccaa tgcagaaagc tggtgggaag   5760

gaattcctca tcatcacttt ctttaatgta gccaatttag gcagggtaat gacggcaata   5820

gagagctgct ccttgtcatt atgagacgtg ggataagaag agtgcaacag tgagccaaac   5880

acattttggt atagttattt ttttcttctt ttgttttctt tcttttttaa cacttagtaa   5940

gcatgagagg agaggtagaa aaataccctt ttttcaacat atagttgtca gatgctttgt   6000

gcatgcaaat catgctttag gcagtgcggt atttcttaaa aactggccaa ttcaccataa   6060

ccaatttccc ttatggatgg actaggctgg tatatacata tttgaaaagt tttacttcaa   6120

agaattccat cgaatagaat aggggtaaaa gggaggagga aaacatgtca cagctgtacc   6180

atctctaaaa aggtgttttt atggtgaatg ttttggattt agattttgga tcccccgtcc   6240

cctcaagcat gatagttttg gatatttgct tgctgtgtga attgacaagc acttttactg   6300

acaaatggtg aggctcagtc agaacctcca ccctccccca caccaaagac aggggcagcg   6360

tagtattcaa accagtattg tggtggggaa taattgtata catgtaaatt atcaagccct   6420

atgagtggaa gaattttttc aaattatttt tgtccctcta tatattgatt tatattatgt   6480

ataactatct ctttatataa actatatata attatatata tataactata taattatata   6540

tatataacta tatatataac tatatatatg tatcccctag tattggatca tgaagagctc   6600

ttcatgcatt ctttgcaaag gaggttataa agttacgccc tcagaacatt tataactata   6660

agaatgtgcc agttaaagtg ctcaacagga aatatgacag tttaaaagca ttgtaaaact   6720

cacatagctt acttctctct ctaaagtgca acaaggatga atagaatggg ccaaggtatg   6780

acaattaatg gttctgcatg acctagccac tgctgggggt tttcttctat aacgttgtcc   6840

ttgtgaaaac ttttgtgaaa ttaaaaaaaa aggagttaca aattttattc tgtt         6894


<210>  7118
<211>  1178
<212>  PRT
<213>  Homo sapiens

<400>  7118

Met Ala Asn Gly Gly Gly Gly Gly Gly Gly Ser Ser Gly Gly Gly Gly 
1               5                   10                  15


Gly Gly Gly Gly Ser Ser Leu Arg Met Ser Ser Asn Ile His Ala Asn 
            20                  25                  30


His Leu Ser Leu Asp Ala Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser 
        35                  40                  45


Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Ser Val His Glu Pro 
    50                  55                  60


Lys Met Asp Ala Leu Ile Ile Pro Val Thr Met Glu Val Pro Cys Asp 
65                  70                  75                  80


Ser Arg Gly Gln Arg Met Trp Trp Ala Phe Leu Ala Ser Ser Met Val 
                85                  90                  95


Thr Phe Phe Gly Gly Leu Phe Ile Ile Leu Leu Trp Arg Thr Leu Lys 
            100                 105                 110


Tyr Leu Trp Thr Val Cys Cys His Cys Gly Gly Lys Thr Lys Glu Ala 
        115                 120                 125


Gln Lys Ile Asn Asn Gly Ser Ser Gln Ala Asp Gly Thr Leu Lys Pro 
    130                 135                 140


Val Asp Glu Lys Glu Glu Ala Val Ala Ala Glu Val Gly Trp Met Thr 
145                 150                 155                 160


Ser Val Lys Asp Trp Ala Gly Val Met Ile Ser Ala Gln Thr Leu Thr 
                165                 170                 175


Gly Arg Val Leu Val Val Leu Val Phe Ala Leu Ser Ile Gly Ala Leu 
            180                 185                 190


Val Ile Tyr Phe Ile Asp Ser Ser Asn Pro Ile Glu Ser Cys Gln Asn 
        195                 200                 205


Phe Tyr Lys Asp Phe Thr Leu Gln Ile Asp Met Ala Phe Asn Val Phe 
    210                 215                 220


Phe Leu Leu Tyr Phe Gly Leu Arg Phe Ile Ala Ala Asn Asp Lys Leu 
225                 230                 235                 240


Trp Phe Trp Leu Glu Val Asn Ser Val Val Asp Phe Phe Thr Val Pro 
                245                 250                 255


Pro Val Phe Val Ser Val Tyr Leu Asn Arg Ser Trp Leu Gly Leu Arg 
            260                 265                 270


Phe Leu Arg Ala Leu Arg Leu Ile Gln Phe Ser Glu Ile Leu Gln Phe 
        275                 280                 285


Leu Asn Ile Leu Lys Thr Ser Asn Ser Ile Lys Leu Val Asn Leu Leu 
    290                 295                 300


Ser Ile Phe Ile Ser Thr Trp Leu Thr Ala Ala Gly Phe Ile His Leu 
305                 310                 315                 320


Val Glu Asn Ser Gly Asp Pro Trp Glu Asn Phe Gln Asn Asn Gln Ala 
                325                 330                 335


Leu Thr Tyr Trp Glu Cys Val Tyr Leu Leu Met Val Thr Met Ser Thr 
            340                 345                 350


Val Gly Tyr Gly Asp Val Tyr Ala Lys Thr Thr Leu Gly Arg Leu Phe 
        355                 360                 365


Met Val Phe Phe Ile Leu Gly Gly Leu Ala Met Phe Ala Ser Tyr Val 
    370                 375                 380


Pro Glu Ile Ile Glu Leu Ile Gly Asn Arg Lys Lys Tyr Gly Gly Ser 
385                 390                 395                 400


Tyr Ser Ala Val Ser Gly Arg Lys His Ile Val Val Cys Gly His Ile 
                405                 410                 415


Thr Leu Glu Ser Val Ser Asn Phe Leu Lys Asp Phe Leu His Lys Asp 
            420                 425                 430


Arg Asp Asp Val Asn Val Glu Ile Val Phe Leu His Asn Ile Ser Pro 
        435                 440                 445


Asn Leu Glu Leu Glu Ala Leu Phe Lys Arg His Phe Thr Gln Val Glu 
    450                 455                 460


Phe Tyr Gln Gly Ser Val Leu Asn Pro His Asp Leu Ala Arg Val Lys 
465                 470                 475                 480


Ile Glu Ser Ala Asp Ala Cys Leu Ile Leu Ala Asn Lys Tyr Cys Ala 
                485                 490                 495


Asp Pro Asp Ala Glu Asp Ala Ser Asn Ile Met Arg Val Ile Ser Ile 
            500                 505                 510


Lys Asn Tyr His Pro Lys Ile Arg Ile Ile Thr Gln Met Leu Gln Tyr 
        515                 520                 525


His Asn Lys Ala His Leu Leu Asn Ile Pro Ser Trp Asn Trp Lys Glu 
    530                 535                 540


Gly Asp Asp Ala Ile Cys Leu Ala Glu Leu Lys Leu Gly Phe Ile Ala 
545                 550                 555                 560


Gln Ser Cys Leu Ala Gln Gly Leu Ser Thr Met Leu Ala Asn Leu Phe 
                565                 570                 575


Ser Met Arg Ser Phe Ile Lys Ile Glu Glu Asp Thr Trp Gln Lys Tyr 
            580                 585                 590


Tyr Leu Glu Gly Val Ser Asn Glu Met Tyr Thr Glu Tyr Leu Ser Ser 
        595                 600                 605


Ala Phe Val Gly Leu Ser Phe Pro Thr Val Cys Glu Leu Cys Phe Val 
    610                 615                 620


Lys Leu Lys Leu Leu Met Ile Ala Ile Glu Tyr Lys Ser Ala Asn Arg 
625                 630                 635                 640


Glu Ser Arg Ile Leu Ile Asn Pro Gly Asn His Leu Lys Ile Gln Glu 
                645                 650                 655


Gly Thr Leu Gly Phe Phe Ile Ala Ser Asp Ala Lys Glu Val Lys Arg 
            660                 665                 670


Ala Phe Phe Tyr Cys Lys Ala Cys His Asp Asp Ile Thr Asp Pro Lys 
        675                 680                 685


Arg Ile Lys Lys Cys Gly Cys Lys Arg Leu Glu Asp Glu Gln Pro Ser 
    690                 695                 700


Thr Leu Ser Pro Lys Lys Lys Gln Arg Asn Gly Gly Met Arg Asn Ser 
705                 710                 715                 720


Pro Asn Thr Ser Pro Lys Leu Met Arg His Asp Pro Leu Leu Ile Pro 
                725                 730                 735


Gly Asn Asp Gln Ile Asp Asn Met Asp Ser Asn Val Lys Lys Tyr Asp 
            740                 745                 750


Ser Thr Gly Met Phe His Trp Cys Ala Pro Lys Glu Ile Glu Lys Val 
        755                 760                 765


Ile Leu Thr Arg Ser Glu Ala Ala Met Thr Val Leu Ser Gly His Val 
    770                 775                 780


Val Val Cys Ile Phe Gly Asp Val Ser Ser Ala Leu Ile Gly Leu Arg 
785                 790                 795                 800


Asn Leu Val Met Pro Leu Arg Ala Ser Asn Phe His Tyr His Glu Leu 
                805                 810                 815


Lys His Ile Val Phe Val Gly Ser Ile Glu Tyr Leu Lys Arg Glu Trp 
            820                 825                 830


Glu Thr Leu His Asn Phe Pro Lys Val Ser Ile Leu Pro Gly Thr Pro 
        835                 840                 845


Leu Ser Arg Ala Asp Leu Arg Ala Val Asn Ile Asn Leu Cys Asp Met 
    850                 855                 860


Cys Val Ile Leu Ser Ala Asn Gln Asn Asn Ile Asp Asp Thr Ser Leu 
865                 870                 875                 880


Gln Asp Lys Glu Cys Ile Leu Ala Ser Leu Asn Ile Lys Ser Met Gln 
                885                 890                 895


Phe Asp Asp Ser Ile Gly Val Leu Gln Ala Asn Ser Gln Gly Phe Thr 
            900                 905                 910


Pro Pro Gly Met Asp Arg Ser Ser Pro Asp Asn Ser Pro Val His Gly 
        915                 920                 925


Met Leu Arg Gln Pro Ser Ile Thr Thr Gly Val Asn Ile Pro Ile Ile 
    930                 935                 940


Thr Glu Leu Val Asn Asp Thr Asn Val Gln Phe Leu Asp Gln Asp Asp 
945                 950                 955                 960


Asp Asp Asp Pro Asp Thr Glu Leu Tyr Leu Thr Gln Pro Phe Ala Cys 
                965                 970                 975


Gly Thr Ala Phe Ala Val Ser Val Leu Asp Ser Leu Met Ser Ala Thr 
            980                 985                 990


Tyr Phe Asn Asp Asn Ile Leu Thr Leu Ile Arg Thr Leu Val Thr Gly 
        995                 1000                1005


Gly Ala Thr Pro Glu Leu Glu Ala Leu Ile Ala Glu Glu Asn Ala Leu 
    1010                1015                1020


Arg Gly Gly Tyr Ser Thr Pro Gln Thr Leu Ala Asn Arg Asp Arg Cys 
1025                1030                1035                1040


Arg Val Ala Gln Leu Ala Leu Leu Asp Gly Pro Phe Ala Asp Leu Gly 
                1045                1050                1055


Asp Gly Gly Cys Tyr Gly Asp Leu Phe Cys Lys Ala Leu Lys Thr Tyr 
            1060                1065                1070


Asn Met Leu Cys Phe Gly Ile Tyr Arg Leu Arg Asp Ala His Leu Ser 
        1075                1080                1085


Thr Pro Ser Gln Cys Thr Lys Arg Tyr Val Ile Thr Asn Pro Pro Tyr 
    1090                1095                1100


Glu Phe Glu Leu Val Pro Thr Asp Leu Ile Phe Cys Leu Met Gln Phe 
1105                1110                1115                1120


Asp His Asn Ala Gly Gln Ser Arg Ala Ser Leu Ser His Ser Ser His 
                1125                1130                1135


Ser Ser Gln Ser Ser Ser Lys Lys Ser Ser Ser Val His Ser Ile Pro 
            1140                1145                1150


Ser Thr Ala Asn Arg Gln Asn Arg Pro Lys Ser Arg Glu Ser Arg Asp 
        1155                1160                1165


Lys Gln Lys Tyr Val Gln Glu Glu Arg Leu 
    1170                1175


<210>  7119
<211>  3178
<212>  DNA
<213>  Homo sapiens

<400>  7119
gcatgtccag agggttgagc cctactcagc ctcatctggg tactgactgg gggccaggac     60

tcaggtccag ccagtttcac agcagagcct gtgctcttgg ccatgatgat aatggcactt    120

tcccacccag tccttttttt tttcaaattt atttattttg agtgctgcat tctctacctt    180

ttatagttaa gaatgttttc aaggtctggt gggaggtttt cgtgttttgc atccatgaat    240

gcagtcagtg tttgcctgta aatagggagg gtcaattctc ttgggctcct ctgctgtgca    300

cctcattgcc catagaatgc tactctcgga tcttgcacta gagcactgga tgatgaagtg    360

aagccttgca gagacctgtg agtctggggg aggaaaccaa gactccaggg tggagtgatt    420

ggctgtatgt ttcacctgca gccacgcgag gcccagaagt cttccagtgc tttggaggtt    480

cacaagaaat atggtgactc aactggaacc acattagagg aggcccagaa gattaacaat    540

ggctcaagcc aggcggatgg cactctcaaa ccagtggatg aaaaagagga ggcagtggcc    600

gccgaggtcg gctggatgac ctccgtgaag gactgggcgg gggtgatgat atccgcccag    660

acactgactg gcagagtcct ggttgtctta gtctttgctc tcagcatcgg tgcacttgta    720

atatacttca tagattcatc aaagtgagta ttcaaatata ctttcttgcc ctcgtttcat    780

aaacaatcat gagcctttac attgatccat ttatttacct tgacaccaac ctttgcaaga    840

ccttctgagt gcagaagatt ttggaggaag ctagtgctgt actgtactga ttttctaaat    900

gggaaagaaa gttctcagaa ggaaggctat tttgagtctg ctggcatagg agggtgaggt    960

atatgaggtc aagtcttctt gctgggtatt acttattttt aaagagctgt ttcctaatga   1020

tgtatttgca ctgaagatgt caagtagtta agatgacttg atgggaattt gcaacttctg   1080

ggagggtgac agtttcccac agatgagggt ctgagccatt cttgctatgg ttgtaggatc   1140

cttttctcaa ttgggtttcc aatgctttga tcttactgga ggtcagatta gaaagcatga   1200

tgctatcctt tcacctgcca atcgggtatt cagctgaagc attgcacgct ggtgcttctt   1260

gacttgtgaa ggtaaggaga tggatggagg agttcatcat gacccccaga ggtggaggcc   1320

ctggccattt gaggacttct agagtggaca ctcatgcaga ctccttgggt gccagccgaa   1380

tggactggtg ctccagagtg agcctgggtg acagatgata aagaccttgc agaaggatga   1440

agagggcaca gactagaact gcaatgttgc agccagttct gccctgattc ctgcaggtgc   1500

caaccctgag gaaataattt gttccaacta tactattgca aatcatgaag ttgatggcat   1560

ctgggaaaca agctggagtc taactcattt tctgttgtgg cgtgaacttg gcaactctgg   1620

tgacaatggc cttgagcttg ttgcctttat tgtccactgt gtgagtgttt tgaactttaa   1680

actctatccc tggcatggtt ggctactaga ctttgatact aggaaacctg cttggtgtgc   1740

ctgttggctc agactctggt gtgcctgaat tctgagctta gtgctccttt cctgtggctt   1800

gggatggtgg taatttcatg cacagctaaa ctcagaattt ctcagagcca tctggtcacc   1860

ggccaaggat tttgtgcatt tgggtggaga ggccaaaatg tcagtcaggg aaaacaaagc   1920

aaatatctcc tttaataacc tgtctctggg aatcagccaa gtttaagcct atcagaggtc   1980

cttcagccca ccccacatgc gaggctgggc tgccctcacc catctcagat ggagagtcct   2040

ttaaacgctg tcaggagaca agattccaca tgctccctcc atcagctctc ccgagccaag   2100

aaagagaaga gcttgtttaa gtttggaaga ctcccattgg catgtcattg aaggtaagcc   2160

cccttttaaa tatttactgt taatgattct ggatcctatt tgtattgaac tgaagatcct   2220

ctaaagcccc tggtcttatt tctccaatct ctctccaggg gtgttcttac atgtcgtggg   2280

gtgcagaccc tgccaacttc catgctgaga ctcaggaaag aggtttgggc ttgaagcttg   2340

tatgtcccag agaaagaaaa ccctaatgtg gaggtgagtg tgttgatggg ttagaagtcc   2400

agatgcctca gccagcacct tccttccctt ttcgtttttt tatttttttt atttttttaa   2460

ccttttgtcc ctctgtattt ctcagaaata aaatgctctt tagatggatt tggattgtgt   2520

ctttttttac agtctactat gaggcagtct tttgttctgt agatcctggt gttctctgtt   2580

tccgtgtgag aagatgaaaa ggaatgaaat tccccaatgc accctcttcc cctaatgtcc   2640

tacaccatct caatgtcctt tggctttaat tgtgatcctt ctaggccttg gcgaagatgg   2700

cactgggagt cctctctgat tctggtttct tttatgaact tgcaaatagt ctatcccaag   2760

gatggaactt cagtcctgtc ctcacctttt cctggcaaaa atgcccataa ggttagaaac   2820

aaggctattc ccattctgcc tgaggactgt cgtagcctca tcccagcttt agcctttctt   2880

ctctgttgct aaactgtgtg atttggcata gcaaggcttt gtttataaga agaccttctg   2940

gttatttata tagaaacttt tcattttcat gacttcattt tgttctgaga gcatatccga   3000

agattctgtc cggtggcagg cccaatcagt ggattcagca caagggagtt ttccatcttc   3060

cttgggaaag acggcaagca agctcagttt tagtttggga gagaattagt gtagaatctc   3120

taaagccatc tctatggtaa gtccatagat ttccaggaat aaaacacagt gaaaccta     3178


<210>  7120
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  7120

Met Phe His Leu Gln Pro Arg Glu Ala Gln Lys Ser Ser Ser Ala Leu 
1               5                   10                  15


Glu Val His Lys Lys Tyr Gly Asp Ser Thr Gly Thr Thr Leu Glu Glu 
            20                  25                  30


Ala Gln Lys Ile Asn Asn Gly Ser Ser Gln Ala Asp Gly Thr Leu Lys 
        35                  40                  45


Pro Val Asp Glu Lys Glu Glu Ala Val Ala Ala Glu Val Gly Trp Met 
    50                  55                  60


Thr Ser Val Lys Asp Trp Ala Gly Val Met Ile Ser Ala Gln Thr Leu 
65                  70                  75                  80


Thr Gly Arg Val Leu Val Val Leu Val Phe Ala Leu Ser Ile Gly Ala 
                85                  90                  95


Leu Val Ile Tyr Phe Ile Asp Ser Ser Lys 
            100                 105


<210>  7121
<211>  422
<212>  DNA
<213>  Homo sapiens

<400>  7121
caggttgcaa cctattagtg gaccatgaga tcagtttcat gagtcctgac cgtcatttta     60

taaatgaaat gagaatggaa tgaaatgaag tggagtggag tgggatggaa tgagatggaa    120

ctagcaggaa ataatagaat attccagaat agaaactatc aaagtacatc acatgtagta    180

aaggattaga aagcaaaagc aatctgaaga ttgaaagtca gaagcaaagt tagaatggtg    240

atttttttcc cccaacccaa cttggaagaa tttgtctttg gagaaccaac ctaatcaaat    300

aaagtagcat caatttactg gagacataat ccaacttgca taattgtcct ggctggttta    360

caccacagct gttcatatga catggttcat taaataataa agtcttcatc aggctctcct    420

gc                                                                   422


<210>  7122
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  7122

Met Lys Trp Ser Gly Val Gly Trp Asn Glu Met Glu Leu Ala Gly Asn 
1               5                   10                  15


Asn Arg Ile Phe Gln Asn Arg Asn Tyr Gln Ser Thr Ser His Val Val 
            20                  25                  30


Lys Asp 



<210>  7123
<211>  1991
<212>  DNA
<213>  Homo sapiens

<400>  7123
ccgcgccccg cccccgccgc tcggacggcc cgagtcgcgc cctcccgccc cgcgccgcgg     60

aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg    120

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    180

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    240

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    300

cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg tgggcgtggt gatgttcacc    360

ctggggttcg ccggctgcgt gggggctctg cgggagaata tctgcttgct caactttttc    420

tgtggcacca tcgtgctcat cttcttcctg gagctggctg tggccgtgct ggccttcctg    480

ttccaggact gggtgaggga ccggttccgg gagttcttcg agagcaacat caagtcctac    540

cgggacgata tcgatctgca aaacctcatc gactcccttc agaaagctaa ccagtgctgt    600

ggcgcatatg gccctgaaga ctgggacctc aacgtctact tcaattgcag cggtgccagc    660

tacagccgag agaagtgcgg ggtccccttc tcctgctgcg tgccagatcc tgcgcaaaaa    720

gttgtgaaca cacagtgtgg atatgatgtc aggattcagc tgaagagcaa gtgggatgag    780

tccatcttca cgaaaggctg catccaggcg ctggaaagct ggctcccgcg gaacatttac    840

attgtggctg gcgtcttcat cgccatctcg ctgttgcaga tatttggcat cttcctggca    900

aggacgctga tctcagacat cgaggcagtg aaggccggcc atcacttctg aggagcagag    960

ttgagggagc cgagctgagc cacgctggga ggccagagcc tttctctgcc atcagcccta   1020

cgtccagagg gagaggagcc gacaccccca gagccagtgc cccatcttaa gcatcagcgt   1080

gacgtgacct ctctgtttct gcttgctggt gctgaagacc aagggtcccc cttgttacct   1140

gcccaaactt gtgactgcat ccctctggag tctacccaga gacagagaat gtgtctttat   1200

gtgggagtgg tgactctgaa agacagagag ggctcctgtg gctgccagga gggcttgact   1260

cagaccccct gcagctcaag catgtctgca ggacaccctg gtcccctctc cactggcatc   1320

caggcatctc tctccatcaa gcaaagcagc atgggggcct gcccgtaacg ggaggcggac   1380

gtggccccgc tgggcctctg agtgccagcg cagtctgctg ggacatgcac atatcagggg   1440

ttgtttgcag ggctcctctt gtggccatgt acccagggct ggctggcctg ccatttgcct   1500

ctccccggag acagccgttc ttctgcaacc acaccccgtg cctagccaca accccaggct   1560

gcagctgctc agaagctcca ggcattttgt ttctggtgac cgcccctaat gggatatcgg   1620

tgatcactgg tccacccttc ctgtcagggc ttttctgggg ctgctcttgg aaatgaagtc   1680

ttaagtactg aataactccc ctggggatag ctggggcatt tgtctagctg ggctactttc   1740

taacactttg ccatagctca gaccacttct catcgttcag ggatggactg caaccttaat   1800

ttacttgccg gagtgtacat tctagtgtgg tgtatactgg tggctgttga tgatgatttt   1860

ttttttttta cacaattctc tgtagactag gagaagaatg cttgtgtttt tcggaagtgt   1920

gatgcttctc tttgactgcc aaactctttt atggaatata tctttatatt aatgctgttt   1980

tggtcatttt t                                                        1991


<210>  7124
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  7124

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Pro Glu 
145                 150                 155                 160


Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser Gly Ala Ser Tyr Ser 
                165                 170                 175


Arg Glu Lys Cys Gly Val Pro Phe Ser Cys Cys Val Pro Asp Pro Ala 
            180                 185                 190


Gln Lys Val Val Asn Thr Gln Cys Gly Tyr Asp Val Arg Ile Gln Leu 
        195                 200                 205


Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys Gly Cys Ile Gln Ala 
    210                 215                 220


Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile Val Ala Gly Val Phe 
225                 230                 235                 240


Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile Phe Leu Ala Arg Thr 
                245                 250                 255


Leu Ile Ser Asp Ile Glu Ala Val Lys Ala Gly His His Phe 
            260                 265                 270


<210>  7125
<211>  1273
<212>  DNA
<213>  Homo sapiens

<400>  7125
ccgcgccccg cccccgccgc tcggacggcc cgagtcgcgc cctcccgccc cgcgccgcgg     60

aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg    120

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    180

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    240

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    300

cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg tgggcgtggt gatgttcacc    360

ctggggttcg ccggctgcgt gggggctctg cgggagaata tctgcttgct caactttttc    420

tgtggcacca tcgtgctcat cttcttcctg gagctggctg tggccgtgct ggccttcctg    480

ttccaggact gggtgaggga ccggttccgg gagttcttcg agagcaacat caagtcctac    540

cgggacgata tcgatctgca aaacctcatc gactcccttc agaaagctaa ccagtgctgt    600

ggcgcatatg gcctcactgt cttctggtct tggtgctact gaaattgtca cccagaattt    660

gaatcctgac cctccccact gcaagcccag ggagccccag cccaagatgg ccagcctgaa    720

actgttggcc agggctcctc ttgtggccat gtacccaggg ctggctggcc tgccatttgc    780

ctctccccgg agacagccgt tcttctgcaa ccacaccccg tgcctagcca caaccccagg    840

ctgcagctgc tcagaagctc caggcatttt gtttctggtg accgccccta atgggatatc    900

ggtgatcact ggtccaccct tcctgtcagg gcttttctgg ggctgctctt ggaaatgaag    960

tcttaagtac tgaataactc ccctggggat agctggggca tttgtctagc tgggctactt   1020

tctaacactt tgccatagct cagaccactt ctcatcgttc agggatggac tgcaacctta   1080

atttacttgc cggagtgtac attctagtgt ggtgtatact ggtggctgtt gatgatgatt   1140

tttttttttt tacacaattc tctgtagact aggagaagaa tgcttgtgtt tttcggaagt   1200

gtgatgcttc tctttgactg ccaaactctt ttatggaata tatctttata ttaatgctgt   1260

tttggtcatt ttt                                                      1273


<210>  7126
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7126

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Leu Thr 
145                 150                 155                 160


Val Phe Trp Ser Trp Cys Tyr 
                165


<210>  7127
<211>  2624
<212>  DNA
<213>  Homo sapiens

<400>  7127
ccgcgccccg cccccgccgc tcggacggcc cgagtcgcgc cctcccgccc cgcgccgcgg     60

aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg    120

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    180

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    240

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    300

cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg tgggcgtggt gatgttcacc    360

ctggggttcg ccggctgcgt gggggctctg cgggagaata tctgcttgct caactttttc    420

tgtggcacca tcgtgctcat cttcttcctg gagctggctg tggccgtgct ggccttcctg    480

ttccaggact gggtgaggga ccggttccgg gagttcttcg agagcaacat caagtcctac    540

cgggacgata tcgatctgca aaacctcatc gactcccttc agaaagctaa ccagtgctgt    600

ggcgcatatg gccctgaaga ctgggacctc aacgtctact tcaattgcag cggtgccagc    660

tacagccgag agaagtgcgg ggtccccttc tcctgctgcg tgccagatcc tgcgcaaaaa    720

gttgtgaaca cacagtgtgg atatgatgtc aggattcagc tgaagagcaa gtgggatgag    780

tccatcttca cgaaaggctg catccaggcg ctggaaagct ggctcccgcg gaacatttac    840

attgtggctg gcgtcttcat cgccatctcg ctgttgcaga tatttggcat cttcctggca    900

aggacgctga tctcagacat cgaggcagtg aaggccggcc atcacttctg aggagcagag    960

ttgagggagc cgagctgagc cacgctggga ggccagagcc tttctctgcc atcagcccta   1020

cgtccagagg gagaggagcc gacaccccca gagccagtgc cccatcttaa gcatcagcgt   1080

gacgtgacct ctctgtttct gcttgctggt gctgaagacc aagggtcccc cttgttacct   1140

gcccaaactt gtgactgcat ccctctggag tctacccaga gacagagaat gtgtctttat   1200

gtgggagtgg tgactctgaa agacagagag ggctcctgtg gctgccagga gggcttgact   1260

cagaccccct gcagctcaag catgtctgca ggacaccctg gtcccctctc cactggcatc   1320

cagacatctg ctttgggtca tccacatctg tgggtgggcc gtgggtagag ggacccacag   1380

gcgtggacag ggcatctctc tccatcaagc aaagcagcat gggggcctgc ccgtaacggg   1440

aggcggacgt ggccccgctg ggcctctgag tgccagcgca gtctgctggg acatgcacat   1500

atcaggggtt gtttgcagga tcctcagcca tgttcaagtg aagtaagcct gagccagtgc   1560

gtggactggt gccacgggag tgccttgtcc actgtccccc tgtgtccacc agctattctc   1620

ctggcgccgg aactgcctct ggtcttgata gcattaagcc ctgatggcgc cggtggcgcg   1680

gtgggcatgg ttcttcactg agagccggct ctccttttct taaagtgtgt aaatagttta   1740

tttatagggg taagaatgtt ctcacaccat ttcacttcct cttcctctcc tccagcattc   1800

tcctctgagc agccttagat agtgtccatg gctggagccg accctttgag tccccttgag   1860

tgtcttaaga accagcccac aacagcctct ctttctcctc cacatactgc agcctccctc   1920

catgcatccc acatacaagc actcccccac tccccagcgt ggcctcactg tcttctggtc   1980

ttggtgctac tgaaattgtc acccagaatt tgaatcctga ccctccccac tgcaagccca   2040

gggagcccca gcccaagatg gccagcctga aactgttggc cagggctcct cttgtggcca   2100

tgtacccagg gctggctggc ctgccatttg cctctccccg gagacagccg ttcttctgca   2160

accacacccc gtgcctagcc acaaccccag gctgcagctg ctcagaagct ccaggcattt   2220

tgtttctggt gaccgcccct aatgggatat cggtgatcac tggtccaccc ttcctgtcag   2280

ggcttttctg gggctgctct tggaaatgaa gtcttaagta ctgaataact cccctgggga   2340

tagctggggc atttgtctag ctgggctact ttctaacact ttgccatagc tcagaccact   2400

tctcatcgtt cagggatgga ctgcaacctt aatttacttg ccggagtgta cattctagtg   2460

tggtgtatac tggtggctgt tgatgatgat tttttttttt ttacacaatt ctctgtagac   2520

taggagaaga atgcttgtgt ttttcggaag tgtgatgctt ctctttgact gccaaactct   2580

tttatggaat atatctttat attaatgctg ttttggtcat tttt                    2624


<210>  7128
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  7128

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Pro Glu 
145                 150                 155                 160


Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser Gly Ala Ser Tyr Ser 
                165                 170                 175


Arg Glu Lys Cys Gly Val Pro Phe Ser Cys Cys Val Pro Asp Pro Ala 
            180                 185                 190


Gln Lys Val Val Asn Thr Gln Cys Gly Tyr Asp Val Arg Ile Gln Leu 
        195                 200                 205


Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys Gly Cys Ile Gln Ala 
    210                 215                 220


Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile Val Ala Gly Val Phe 
225                 230                 235                 240


Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile Phe Leu Ala Arg Thr 
                245                 250                 255


Leu Ile Ser Asp Ile Glu Ala Val Lys Ala Gly His His Phe 
            260                 265                 270


<210>  7129
<211>  2694
<212>  DNA
<213>  Homo sapiens

<400>  7129
ccgcgccccg cccccgccgc tcggacggcc cgagtcgcgc cctcccgccc cgcgccgcgg     60

aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg    120

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    180

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    240

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    300

cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg tgggcgtggt gatgttcacc    360

ctggggttcg ccggctgcgt gggggctctg cgggagaata tctgcttgct caactttttc    420

tgtggcacca tcgtgctcat cttcttcctg gagctggctg tggccgtgct ggccttcctg    480

ttccaggact gggtgaggga ccggttccgg gagttcttcg agagcaacat caagtcctac    540

cgggacgata tcgatctgca aaacctcatc gactcccttc agaaagctaa ccagtgctgt    600

ggcgcatatg gcctcactgt cttctggtct tggtgctact gaaattgtca cccagaattt    660

gaatcctgac cctccccact gcaagcccag ggagccccag cccaagatgg ccagcctgaa    720

actgttggcc agggctcctc ttgtggccat gtacccaggg ctggctggcc tgccatttgc    780

ctctccccgg agacagccgt tcttctgcaa ccacaccccg tgcctagcca caaccccagg    840

ctgcagctgc tcagaagctc caggcatttt gtttctggtg accgccccta atgggatatc    900

ggtgatcact ggtccaccct tcctgtcagg gcttttctgg ggctgctctt ggaaatgaag    960

tcttaagtac tgaataactc ccctggggat agctggggca tttgtctagc tgggctactt   1020

tctaacactt tgccatagct cagaccactt ctcatcgttc agggatggac tgcaacctta   1080

atttacttgc cggagtgtac attctagtgt ggtgtatact ggtggctgtt gatgatgatt   1140

tttttttttt tacacaattc tctgtagact aggagaagaa tgcttgtgtt tttcggaagt   1200

gtgatgcttc tctttgactg ccaaactctt ttatggaata tatctttata ttaatgctgt   1260

tttggtcatt tttgtttggg gtcactattg agatattgct aagcatctca gtggtaaacg   1320

cggctgccag aggaaccaag ggatagggta tgtagacctt acagaaggat ggatggtaaa   1380

ggcagtccat catcagcaca atctgactta catttcattg agtaattttt ttttttttta   1440

agattctgta tggcagcact ttcagttgcc cttgtgtgcc ggccacagcc gcacaagttg   1500

gcttgtggtt tatcccccgc tataagtgag agctggagaa acttcaactc cataggtcta   1560

gaggaaacat tgttttaggt tatttctgtc cacccctgtg cgatactatt tattgatcca   1620

agcagaagag cttggggaca ctgagtcgaa gtggggacat gggattgaag cctgggcact   1680

gctgctgcat gagctgtgtg tcctgggtgt gccggccttt ctgtgaaggg ggttggtggc   1740

agtgcccacc tcactagatg cctctgaccc agcctcccct gggggagtgg gtggccacag   1800

accctccctg ccagagctcc tggaaggctc ctgcaggcct gacccatcta ttcctgtaga   1860

cctggtttag gatgaagtct cggtgcgatt tttgcagagt tgggtttatc tttcaactat   1920

agacccttct ggctgttctc agccatatca tgtgactctg aatagttgga tgaggaatgg   1980

aaagaaagca aggatgagag ccggtcacgt ggcagtctcc gcccagcatc ggctgtccgc   2040

acagaggcac agggcaggcc tcctgtgcac tccccaccta gcactggcct gtcctgaatc   2100

cccgccttcc ctggttggag gccagctgtg gcatttgcac cctcttctca cctcaccatg   2160

cacatgctaa ctttaaagcc ttggggtctt tcctgtaccc cctcctcaac cctggtccac   2220

cccctctcag gatcttgtca acgttatttt tcctgtcccg tcttcctatc gctggccttc   2280

ctttcccatc ctaaaaactt gccgaggccc tatggctccc tccctttctt tcccaggcag   2340

cttcttatct gggctgtctg taccccttcc tttgcaccac ccaccatgcc ccacgtagct   2400

gaaagctgct tatcccaatt gtcaactctg gccttcttca gcctctgtag caccagacac   2460

tgcacctcct gaatgtcctc tgcttctctg cttcagaggc ccaggctcgc cagttctctg   2520

acctctccca tatgtctgct taggactctg ctgcagctgt cctcaccagc ctccggggaa   2580

tcccactacc cacagggcag ggctgtgggc tgggctgaaa aaccatctgc atggtccaca   2640

agaagcctgg cactgggttt ccccatgaat aacaatgaaa attaatggat gcac         2694


<210>  7130
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7130

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Leu Thr 
145                 150                 155                 160


Val Phe Trp Ser Trp Cys Tyr 
                165


<210>  7131
<211>  4809
<212>  DNA
<213>  Homo sapiens

<400>  7131
ccgcgccccg cccccgccgc tcggacggcc cgagtcgcgc cctcccgccc cgcgccgcgg     60

aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg    120

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    180

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    240

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    300

cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg tgggcgtggt gatgttcacc    360

ctggggttcg ccggctgcgt gggggctctg cgggagaata tctgcttgct caactttttc    420

tgtggcacca tcgtgctcat cttcttcctg gagctggctg tggccgtgct ggccttcctg    480

ttccaggact gggtgaggga ccggttccgg gagttcttcg agagcaacat caagtcctac    540

cgggacgata tcgatctgca aaacctcatc gactcccttc agaaagctaa ccagtgctgt    600

ggcgcatatg gcctcactgt cttctggtct tggtgctact gaaattgtca cccagaattt    660

gaatcctgac cctccccact gcaagcccag ggagccccag cccaagatgg ccagcctgaa    720

actgttggcc agggctcctc ttgtggccat gtacccaggg ctggctggcc tgccatttgc    780

ctctccccgg agacagccgt tcttctgcaa ccacaccccg tgcctagcca caaccccagg    840

ctgcagctgc tcagaagctc caggcatttt gtttctggtg accgccccta atgggatatc    900

ggtgatcact ggtccaccct tcctgtcagg gcttttctgg ggctgctctt ggaaatgaag    960

tcttaagtac tgaataactc ccctggggat agctggggca tttgtctagc tgggctactt   1020

tctaacactt tgccatagct cagaccactt ctcatcgttc agggatggac tgcaacctta   1080

atttacttgc cggagtgtac attctagtgt ggtgtatact ggtggctgtt gatgatgatt   1140

tttttttttt tacacaattc tctgtagact aggagaagaa tgcttgtgtt tttcggaagt   1200

gtgatgcttc tctttgactg ccaaactctt ttatggaata tatctttata ttaatgctgt   1260

tttggtcatt tttgtttggg gtcactattg agatattgct aagcatctca gtggtaaacg   1320

cggctgccag aggaaccaag ggatagggta tgtagacctt acagaaggat ggatggtaaa   1380

ggcagtccat catcagcaca atctgactta catttcattg agtaattttt ttttttttta   1440

agattctgta tggcagcact ttcagttgcc cttgtgtgcc ggccacagcc gcacaagttg   1500

gcttgtggtt tatcccccgc tataagtgag agctggagaa acttcaactc cataggtcta   1560

gaggaaacat tgttttaggt tatttctgtc cacccctgtg cgatactatt tattgatcca   1620

agcagaagag cttggggaca ctgagtcgaa gtggggacat gggattgaag cctgggcact   1680

gctgctgcat gagctgtgtg tcctgggtgt gccggccttt ctgtgaaggg ggttggtggc   1740

agtgcccacc tcactagatg cctctgaccc agcctcccct gggggagtgg gtggccacag   1800

accctccctg ccagagctcc tggaaggctc ctgcaggcct gacccatcta ttcctgtaga   1860

cctggtttag gatgaagtct cggtgcgatt tttgcagagt tgggtttatc tttcaactat   1920

agacccttct ggctgttctc agccatatca tgtgactctg aatagttgga tgaggaatgg   1980

aaagaaagca aggatgagag ccggtcacgt ggcagtctcc gcccagcatc ggctgtccgc   2040

acagaggcac agggcaggcc tcctgtgcac tccccaccta gcactggcct gtcctgaatc   2100

cccgccttcc ctggttggag gccagctgtg gcatttgcac cctcttctca cctcaccatg   2160

cacatgctaa ctttaaagcc ttggggtctt tcctgtaccc cctcctcaac cctggtccac   2220

cccctctcag gatcttgtca acgttatttt tcctgtcccg tcttcctatc gctggccttc   2280

ctttcccatc ctaaaaactt gccgaggccc tatggctccc tccctttctt tcccaggcag   2340

cttcttatct gggctgtctg taccccttcc tttgcaccac ccaccatgcc ccacgtagct   2400

gaaagctgct tatcccaatt gtcaactctg gccttcttca gcctctgtag caccagacac   2460

tgcacctcct gaatgtcctc tgcttctctg cttcagaggc ccaggctcgc cagttctctg   2520

acctctccca tatgtctgct taggactctg ctgcagctgt cctcaccagc ctccggggaa   2580

tcccactacc cacagggcag ggctgtgggc tgggctgaaa aaccatctgc atggtccaca   2640

agaagcctgg cactgggttt ccccatgaat aacaatgaaa attaatggat gcacaacctt   2700

cctggaacgt ggaatttctc tgggagattc catgcagagg ccactgggga ggtggcaggc   2760

atgcatgtga ctgtaggtgg ctgcagtgtt ggaaggctcc cagcagagca gagagggtgt   2820

cagtctcatc agggaaccca cctgatggct tctcagccag cagtctcaga ggaacataga   2880

cgactgctga gaaaggaggg aggcagcagt ggtcccagca cctgaggcat cctgctgtca   2940

tgggaaggtc tccgcccaaa tgtcagatgc atcagcctgt cacccgctgg tccagagctt   3000

tcagctgtac tggtaggggg tgggtggtgg agtgctgaat gaccttcaca ggtgggcctt   3060

tccagctcta gggtcttacg ggtgtcggtc cacagaacca cggtttttag gttgtgtgtc   3120

cggggctatg ggaacctgtc ccccatgatg gatcttggta gagacacttc cctctgtcat   3180

cgtgcccagg aggatgctgc aggtgactac ctgcagccct gttctcattc atttggatgc   3240

cctccagaaa tctggggagc catacacctt tagagccttt tttgctcctt atcaagttgg   3300

caaggcttgg ccaattcctg ttcaaggctg cattaaaggc atgttcacca tcctggctaa   3360

tacggtgaaa ccccttctct actaaaaata caaaaaaatt agccgggctt ggtggcgggt   3420

gcctgtagtc ccagctactc cggaggctga ggcaggggaa tggtgtgaac ccaggaggcg   3480

gagcttgcag tgagccgaga tcacaccact gcactccagc ctgggctcaa aaaagaaaaa   3540

aaaaaaaaaa aaaaggcccg ttcattctca aatgcttttg gcgtctccag ggtgcctcag   3600

gaaaacatga agtgggcatt gtagaacttg gggctactgt gtaactttgg aagaaaaagt   3660

taagggtact tttaagtgga tactgttttg atgaaattgc caacttcagg gagcccagct   3720

tggagaagga ggacgtgagt attccttaca aggctccgaa acaattcttt cttcacttag   3780

ttttctttct gtgctctgca tcttatattc cagcagggtc ttccaatgca tggtttaata   3840

actactagaa ctggccaggt gcagtggctc acgcctgtaa tcccagaact ttgggaggct   3900

aagacaggca gatcacttga ggccaggagt tcgagaccag cctggacaac atggtgatac   3960

ccagtttcta ctaaaaatac aaaaattagt cgggcatggt gatgtgcacc tgtagtccca   4020

gctgctcggg aggctgaggc aggagaatcg cttgaacccg ggagacagag gttgcaacga   4080

gccaagatcg agccactgcg ctccggcctg ggtgacagga gactccatct caaaaaataa   4140

aattaaaaaa aaactactac aataaattat caccttggac tgtataaaac aacttttaaa   4200

ctagtctttt taaaaagtac acttaaataa aaatctaaac ataagagaat gtaaagtgaa   4260

aagtgaaagt atgtcttctg ttacgcagag gtaactacta ttaggaatcc ttcctgaaaa   4320

tgtccatgca tctactcagg tcatcacacc catggaatca ttttacatac tattttatga   4380

gtgttactta atatactgat ccacagtgcg ttttcacggt cacgccatca gttgtaggag   4440

tgtgccaaga acagatgggc cttgcctttg taccagagga gtccatttac agttgcaggt   4500

aatagaaaac ccaattcaga ctggcctaaa caatgagggg aggttttggc tcttgaaact   4560

ggaaagtccc aaggtggggt gagtttcagg tttgggttga tccaagtggc tcagtgacgt   4620

caacaggatc ttgtttccat ttctctgcct tccacagcct ccccttcatc tatggtggag   4680

ggaaggagtc taccacagac aaaccccgag cctccccctg atgggtggtg tggtggtgaa   4740

gccagcaagg gaagggatcc ccggacacac ccctcctcat gctttatccc actgaaacca   4800

tgcggctgt                                                           4809


<210>  7132
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7132

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Leu Thr 
145                 150                 155                 160


Val Phe Trp Ser Trp Cys Tyr 
                165


<210>  7133
<211>  2241
<212>  DNA
<213>  Homo sapiens

<400>  7133
cgccgctcgg acggcccgag tcgcgccctc ccgccccgcg ccgcggaact tgctctaact     60

tcctcggccg agccgggccg cgccgccgct gccgccgccg cgcgcggatt ctgcttctca    120

gaagatgcac tattatagat actctaacgc caaggtcagc tgctggtaca agtacctcct    180

tttcagctac aacatcatct tctggaacca gtgctgtggc gcatatggcc ctgaagactg    240

ggacctcaac gtctacttca attgcagcgg tgccagctac agccgagaga agtgcggggt    300

ccccttctcc tgctgcgtgc cagatcctgc gcaaaaagtt gtgaacacac agtgtggata    360

tgatgtcagg attcagctga agagcaagtg ggatgagtcc atcttcacga aaggctgcat    420

ccaggcgctg gaaagctggc tcccgcggaa catttacatt gtggctggcg tcttcatcgc    480

catctcgctg ttgcagatat ttggcatctt cctggcaagg acgctgatct cagacatcga    540

ggcagtgaag gccggccatc acttctgagg agcagagttg agggagccga gctgagccac    600

gctgggaggc cagagccttt ctctgccatc agccctacgt ccagagggag aggagccgac    660

acccccagag ccagtgcccc atcttaagca tcagcgtgac gtgacctctc tgtttctgct    720

tgctggtgct gaagaccaag ggtccccctt gttacctgcc caaacttgtg actgcatccc    780

tctggagtct acccagagac agagaatgtg tctttatgtg ggagtggtga ctctgaaaga    840

cagagagggc tcctgtggct gccaggaggg cttgactcag accccctgca gctcaagcat    900

gtctgcagga caccctggtc ccctctccac tggcatccag acatctgctt tgggtcatcc    960

acatctgtgg gtgggccgtg ggtagaggga cccacaggcg tggacagggc atctctctcc   1020

atcaagcaaa gcagcatggg ggcctgcccg taacgggagg cggacgtggc cccgctgggc   1080

ctctgagtgc cagcgcagtc tgctgggaca tgcacatatc aggggttgtt tgcaggatcc   1140

tcagccatgt tcaagtgaag taagcctgag ccagtgcgtg gactggtgcc acgggagtgc   1200

cttgtccact gtccccctgt gtccaccagc tattctcctg gcgccggaac tgcctctggt   1260

cttgatagca ttaagccctg atggcgccgg tggcgcggtg ggcatggttc ttcactgaga   1320

gccggctctc cttttcttaa agtgtgtaaa tagtttattt ataggggtaa gaatgttctc   1380

acaccatttc acttcctctt cctctcctcc agcattctcc tctgagcagc cttagatagt   1440

gtccatggct ggagccgacc ctttgagtcc ccttgagtgt cttaagaacc agcccacaac   1500

agcctctctt tctcctccac atactgcagc ctccctccat gcatcccaca tacaagcact   1560

cccccactcc ccagcgtggc ctcactgtct tctggtcttg gtgctactga aattgtcacc   1620

cagaatttga atcctgaccc tccccactgc aagcccaggg agccccagcc caagatggcc   1680

agcctgaaac tgttggccag ggctcctctt gtggccatgt acccagggct ggctggcctg   1740

ccatttgcct ctccccggag acagccgttc ttctgcaacc acaccccgtg cctagccaca   1800

accccaggct gcagctgctc agaagctcca ggcattttgt ttctggtgac cgcccctaat   1860

gggatatcgg tgatcactgg tccacccttc ctgtcagggc ttttctgggg ctgctcttgg   1920

aaatgaagtc ttaagtactg aataactccc ctggggatag ctggggcatt tgtctagctg   1980

ggctactttc taacactttg ccatagctca gaccacttct catcgttcag ggatggactg   2040

caaccttaat ttacttgccg gagtgtacat tctagtgtgg tgtatactgg tggctgttga   2100

tgatgatttt ttttttttta cacaattctc tgtagactag gagaagaatg cttgtgtttt   2160

tcggaagtgt gatgcttctc tttgactgcc aaactctttt atggaatata tctttatatt   2220

aatgctgttt tggtcatttt t                                             2241


<210>  7134
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  7134

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Asn Gln Cys Cys Gly 
            20                  25                  30


Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser 
        35                  40                  45


Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys Cys 
    50                  55                  60


Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr Asp 
65                  70                  75                  80


Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys 
                85                  90                  95


Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile 
            100                 105                 110


Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile 
        115                 120                 125


Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala Gly 
    130                 135                 140


His His Phe 
145


<210>  7135
<211>  3662
<212>  DNA
<213>  Homo sapiens

<400>  7135
cgccgctcgg acggcccgag tcgcgccctc ccgccccgcg ccgcggaact tgctctaact     60

tcctcggccg agccgggccg cgccgccgct gccgccgccg cgcgcggatt ctgcttctca    120

gaagatgcac tattatagat actctaacgc caaggtcagc tgctggtaca agtacctcct    180

tttcagctac aacatcatct tctggaacca gtgctgtggc gcatatggcc ctgaagactg    240

ggacctcaac gtctacttca attgcagcgg tgccagctac agccgagaga agtgcggggt    300

ccccttctcc tgctgcgtgc cagatcctgc gcaaaaagtt gtgaacacac agtgtggata    360

tgatgtcagg attcagctga agagcaagtg ggatgagtcc atcttcacga aaggctgcat    420

ccaggcgctg gaaagctggc tcccgcggaa catttacatt gtggctggcg tcttcatcgc    480

catctcgctg ttgcagatat ttggcatctt cctggcaagg acgctgatct cagacatcga    540

ggcagtgaag gccggccatc acttctgagg agcagagttg agggagccga gctgagccac    600

gctgggaggc cagagccttt ctctgccatc agccctacgt ccagagggag aggagccgac    660

acccccagag ccagtgcccc atcttaagca tcagcgtgac gtgacctctc tgtttctgct    720

tgctggtgct gaagaccaag ggtccccctt gttacctgcc caaacttgtg actgcatccc    780

tctggagtct acccagagac agagaatgtg tctttatgtg ggagtggtga ctctgaaaga    840

cagagagggc tcctgtggct gccaggaggg cttgactcag accccctgca gctcaagcat    900

gtctgcagga caccctggtc ccctctccac tggcatccag acatctgctt tgggtcatcc    960

acatctgtgg gtgggccgtg ggtagaggga cccacaggcg tggacagggc atctctctcc   1020

atcaagcaaa gcagcatggg ggcctgcccg taacgggagg cggacgtggc cccgctgggc   1080

ctctgagtgc cagcgcagtc tgctgggaca tgcacatatc aggggttgtt tgcaggatcc   1140

tcagccatgt tcaagtgaag taagcctgag ccagtgcgtg gactggtgcc acgggagtgc   1200

cttgtccact gtccccctgt gtccaccagc tattctcctg gcgccggaac tgcctctggt   1260

cttgatagca ttaagccctg atggcgccgg tggcgcggtg ggcatggttc ttcactgaga   1320

gccggctctc cttttcttaa agtgtgtaaa tagtttattt ataggggtaa gaatgttctc   1380

acaccatttc acttcctctt cctctcctcc agcattctcc tctgagcagc cttagatagt   1440

gtccatggct ggagccgacc ctttgagtcc ccttgagtgt cttaagaacc agcccacaac   1500

agcctctctt tctcctccac atactgcagc ctccctccat gcatcccaca tacaagcact   1560

cccccactcc ccagcgtggc ctcactgtct tctggtcttg gtgctactga aattgtcacc   1620

cagaatttga atcctgaccc tccccactgc aagcccaggg agccccagcc caagatggcc   1680

agcctgaaac tgttggccag ggctcctctt gtggccatgt acccagggct ggctggcctg   1740

ccatttgcct ctccccggag acagccgttc ttctgcaacc acaccccgtg cctagccaca   1800

accccaggct gcagctgctc agaagctcca ggcattttgt ttctggtgac cgcccctaat   1860

gggatatcgg tgatcactgg tccacccttc ctgtcagggc ttttctgggg ctgctcttgg   1920

aaatgaagtc ttaagtactg aataactccc ctggggatag ctggggcatt tgtctagctg   1980

ggctactttc taacactttg ccatagctca gaccacttct catcgttcag ggatggactg   2040

caaccttaat ttacttgccg gagtgtacat tctagtgtgg tgtatactgg tggctgttga   2100

tgatgatttt ttttttttta cacaattctc tgtagactag gagaagaatg cttgtgtttt   2160

tcggaagtgt gatgcttctc tttgactgcc aaactctttt atggaatata tctttatatt   2220

aatgctgttt tggtcatttt tgtttggggt cactattgag atattgctaa gcatctcagt   2280

ggtaaacgcg gctgccagag gaaccaaggg atagggtatg tagaccttac agaaggatgg   2340

atggtaaagg cagtccatca tcagcacaat ctgacttaca tttcattgag taattttttt   2400

tttttttaag attctgtatg gcagcacttt cagttgccct tgtgtgccgg ccacagccgc   2460

acaagttggc ttgtggttta tcccccgcta taagtgagag ctggagaaac ttcaactcca   2520

taggtctaga ggaaacattg ttttaggtta tttctgtcca cccctgtgcg atactattta   2580

ttgatccaag cagaagagct tggggacact gagtcgaagt ggggacatgg gattgaagcc   2640

tgggcactgc tgctgcatga gctgtgtgtc ctgggtgtgc cggcctttct gtgaaggggg   2700

ttggtggcag tgcccacctc actagatgcc tctgacccag cctcccctgg gggagtgggt   2760

ggccacagac cctccctgcc agagctcctg gaaggctcct gcaggcctga cccatctatt   2820

cctgtagacc tggtttagga tgaagtctcg gtgcgatttt tgcagagttg ggtttatctt   2880

tcaactatag acccttctgg ctgttctcag ccatatcatg tgactctgaa tagttggatg   2940

aggaatggaa agaaagcaag gatgagagcc ggtcacgtgg cagtctccgc ccagcatcgg   3000

ctgtccgcac agaggcacag ggcaggcctc ctgtgcactc cccacctagc actggcctgt   3060

cctgaatccc cgccttccct ggttggaggc cagctgtggc atttgcaccc tcttctcacc   3120

tcaccatgca catgctaact ttaaagcctt ggggtctttc ctgtaccccc tcctcaaccc   3180

tggtccaccc cctctcagga tcttgtcaac gttatttttc ctgtcccgtc ttcctatcgc   3240

tggccttcct ttcccatcct aaaaacttgc cgaggcccta tggctccctc cctttctttc   3300

ccaggcagct tcttatctgg gctgtctgta ccccttcctt tgcaccaccc accatgcccc   3360

acgtagctga aagctgctta tcccaattgt caactctggc cttcttcagc ctctgtagca   3420

ccagacactg cacctcctga atgtcctctg cttctctgct tcagaggccc aggctcgcca   3480

gttctctgac ctctcccata tgtctgctta ggactctgct gcagctgtcc tcaccagcct   3540

ccggggaatc ccactaccca cagggcaggg ctgtgggctg ggctgaaaaa ccatctgcat   3600

ggtccacaag aagcctggca ctgggtttcc ccatgaataa caatgaaaat taatggatgc   3660

ac                                                                  3662


<210>  7136
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  7136

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Asn Gln Cys Cys Gly 
            20                  25                  30


Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser 
        35                  40                  45


Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys Cys 
    50                  55                  60


Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr Asp 
65                  70                  75                  80


Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys 
                85                  90                  95


Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile 
            100                 105                 110


Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile 
        115                 120                 125


Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala Gly 
    130                 135                 140


His His Phe 
145


<210>  7137
<211>  5777
<212>  DNA
<213>  Homo sapiens

<400>  7137
cgccgctcgg acggcccgag tcgcgccctc ccgccccgcg ccgcggaact tgctctaact     60

tcctcggccg agccgggccg cgccgccgct gccgccgccg cgcgcggatt ctgcttctca    120

gaagatgcac tattatagat actctaacgc caaggtcagc tgctggtaca agtacctcct    180

tttcagctac aacatcatct tctggaacca gtgctgtggc gcatatggcc ctgaagactg    240

ggacctcaac gtctacttca attgcagcgg tgccagctac agccgagaga agtgcggggt    300

ccccttctcc tgctgcgtgc cagatcctgc gcaaaaagtt gtgaacacac agtgtggata    360

tgatgtcagg attcagctga agagcaagtg ggatgagtcc atcttcacga aaggctgcat    420

ccaggcgctg gaaagctggc tcccgcggaa catttacatt gtggctggcg tcttcatcgc    480

catctcgctg ttgcagatat ttggcatctt cctggcaagg acgctgatct cagacatcga    540

ggcagtgaag gccggccatc acttctgagg agcagagttg agggagccga gctgagccac    600

gctgggaggc cagagccttt ctctgccatc agccctacgt ccagagggag aggagccgac    660

acccccagag ccagtgcccc atcttaagca tcagcgtgac gtgacctctc tgtttctgct    720

tgctggtgct gaagaccaag ggtccccctt gttacctgcc caaacttgtg actgcatccc    780

tctggagtct acccagagac agagaatgtg tctttatgtg ggagtggtga ctctgaaaga    840

cagagagggc tcctgtggct gccaggaggg cttgactcag accccctgca gctcaagcat    900

gtctgcagga caccctggtc ccctctccac tggcatccag acatctgctt tgggtcatcc    960

acatctgtgg gtgggccgtg ggtagaggga cccacaggcg tggacagggc atctctctcc   1020

atcaagcaaa gcagcatggg ggcctgcccg taacgggagg cggacgtggc cccgctgggc   1080

ctctgagtgc cagcgcagtc tgctgggaca tgcacatatc aggggttgtt tgcaggatcc   1140

tcagccatgt tcaagtgaag taagcctgag ccagtgcgtg gactggtgcc acgggagtgc   1200

cttgtccact gtccccctgt gtccaccagc tattctcctg gcgccggaac tgcctctggt   1260

cttgatagca ttaagccctg atggcgccgg tggcgcggtg ggcatggttc ttcactgaga   1320

gccggctctc cttttcttaa agtgtgtaaa tagtttattt ataggggtaa gaatgttctc   1380

acaccatttc acttcctctt cctctcctcc agcattctcc tctgagcagc cttagatagt   1440

gtccatggct ggagccgacc ctttgagtcc ccttgagtgt cttaagaacc agcccacaac   1500

agcctctctt tctcctccac atactgcagc ctccctccat gcatcccaca tacaagcact   1560

cccccactcc ccagcgtggc ctcactgtct tctggtcttg gtgctactga aattgtcacc   1620

cagaatttga atcctgaccc tccccactgc aagcccaggg agccccagcc caagatggcc   1680

agcctgaaac tgttggccag ggctcctctt gtggccatgt acccagggct ggctggcctg   1740

ccatttgcct ctccccggag acagccgttc ttctgcaacc acaccccgtg cctagccaca   1800

accccaggct gcagctgctc agaagctcca ggcattttgt ttctggtgac cgcccctaat   1860

gggatatcgg tgatcactgg tccacccttc ctgtcagggc ttttctgggg ctgctcttgg   1920

aaatgaagtc ttaagtactg aataactccc ctggggatag ctggggcatt tgtctagctg   1980

ggctactttc taacactttg ccatagctca gaccacttct catcgttcag ggatggactg   2040

caaccttaat ttacttgccg gagtgtacat tctagtgtgg tgtatactgg tggctgttga   2100

tgatgatttt ttttttttta cacaattctc tgtagactag gagaagaatg cttgtgtttt   2160

tcggaagtgt gatgcttctc tttgactgcc aaactctttt atggaatata tctttatatt   2220

aatgctgttt tggtcatttt tgtttggggt cactattgag atattgctaa gcatctcagt   2280

ggtaaacgcg gctgccagag gaaccaaggg atagggtatg tagaccttac agaaggatgg   2340

atggtaaagg cagtccatca tcagcacaat ctgacttaca tttcattgag taattttttt   2400

tttttttaag attctgtatg gcagcacttt cagttgccct tgtgtgccgg ccacagccgc   2460

acaagttggc ttgtggttta tcccccgcta taagtgagag ctggagaaac ttcaactcca   2520

taggtctaga ggaaacattg ttttaggtta tttctgtcca cccctgtgcg atactattta   2580

ttgatccaag cagaagagct tggggacact gagtcgaagt ggggacatgg gattgaagcc   2640

tgggcactgc tgctgcatga gctgtgtgtc ctgggtgtgc cggcctttct gtgaaggggg   2700

ttggtggcag tgcccacctc actagatgcc tctgacccag cctcccctgg gggagtgggt   2760

ggccacagac cctccctgcc agagctcctg gaaggctcct gcaggcctga cccatctatt   2820

cctgtagacc tggtttagga tgaagtctcg gtgcgatttt tgcagagttg ggtttatctt   2880

tcaactatag acccttctgg ctgttctcag ccatatcatg tgactctgaa tagttggatg   2940

aggaatggaa agaaagcaag gatgagagcc ggtcacgtgg cagtctccgc ccagcatcgg   3000

ctgtccgcac agaggcacag ggcaggcctc ctgtgcactc cccacctagc actggcctgt   3060

cctgaatccc cgccttccct ggttggaggc cagctgtggc atttgcaccc tcttctcacc   3120

tcaccatgca catgctaact ttaaagcctt ggggtctttc ctgtaccccc tcctcaaccc   3180

tggtccaccc cctctcagga tcttgtcaac gttatttttc ctgtcccgtc ttcctatcgc   3240

tggccttcct ttcccatcct aaaaacttgc cgaggcccta tggctccctc cctttctttc   3300

ccaggcagct tcttatctgg gctgtctgta ccccttcctt tgcaccaccc accatgcccc   3360

acgtagctga aagctgctta tcccaattgt caactctggc cttcttcagc ctctgtagca   3420

ccagacactg cacctcctga atgtcctctg cttctctgct tcagaggccc aggctcgcca   3480

gttctctgac ctctcccata tgtctgctta ggactctgct gcagctgtcc tcaccagcct   3540

ccggggaatc ccactaccca cagggcaggg ctgtgggctg ggctgaaaaa ccatctgcat   3600

ggtccacaag aagcctggca ctgggtttcc ccatgaataa caatgaaaat taatggatgc   3660

acaaccttcc tggaacgtgg aatttctctg ggagattcca tgcagaggcc actggggagg   3720

tggcaggcat gcatgtgact gtaggtggct gcagtgttgg aaggctccca gcagagcaga   3780

gagggtgtca gtctcatcag ggaacccacc tgatggcttc tcagccagca gtctcagagg   3840

aacatagacg actgctgaga aaggagggag gcagcagtgg tcccagcacc tgaggcatcc   3900

tgctgtcatg ggaaggtctc cgcccaaatg tcagatgcat cagcctgtca cccgctggtc   3960

cagagctttc agctgtactg gtagggggtg ggtggtggag tgctgaatga ccttcacagg   4020

tgggcctttc cagctctagg gtcttacggg tgtcggtcca cagaaccacg gtttttaggt   4080

tgtgtgtccg gggctatggg aacctgtccc ccatgatgga tcttggtaga gacacttccc   4140

tctgtcatcg tgcccaggag gatgctgcag gtgactacct gcagccctgt tctcattcat   4200

ttggatgccc tccagaaatc tggggagcca tacaccttta gagccttttt tgctccttat   4260

caagttggca aggcttggcc aattcctgtt caaggctgca ttaaaggcat gttcaccatc   4320

ctggctaata cggtgaaacc ccttctctac taaaaataca aaaaaattag ccgggcttgg   4380

tggcgggtgc ctgtagtccc agctactccg gaggctgagg caggggaatg gtgtgaaccc   4440

aggaggcgga gcttgcagtg agccgagatc acaccactgc actccagcct gggctcaaaa   4500

aagaaaaaaa aaaaaaaaaa aaggcccgtt cattctcaaa tgcttttggc gtctccaggg   4560

tgcctcagga aaacatgaag tgggcattgt agaacttggg gctactgtgt aactttggaa   4620

gaaaaagtta agggtacttt taagtggata ctgttttgat gaaattgcca acttcaggga   4680

gcccagcttg gagaaggagg acgtgagtat tccttacaag gctccgaaac aattctttct   4740

tcacttagtt ttctttctgt gctctgcatc ttatattcca gcagggtctt ccaatgcatg   4800

gtttaataac tactagaact ggccaggtgc agtggctcac gcctgtaatc ccagaacttt   4860

gggaggctaa gacaggcaga tcacttgagg ccaggagttc gagaccagcc tggacaacat   4920

ggtgataccc agtttctact aaaaatacaa aaattagtcg ggcatggtga tgtgcacctg   4980

tagtcccagc tgctcgggag gctgaggcag gagaatcgct tgaacccggg agacagaggt   5040

tgcaacgagc caagatcgag ccactgcgct ccggcctggg tgacaggaga ctccatctca   5100

aaaaataaaa ttaaaaaaaa actactacaa taaattatca ccttggactg tataaaacaa   5160

cttttaaact agtcttttta aaaagtacac ttaaataaaa atctaaacat aagagaatgt   5220

aaagtgaaaa gtgaaagtat gtcttctgtt acgcagaggt aactactatt aggaatcctt   5280

cctgaaaatg tccatgcatc tactcaggtc atcacaccca tggaatcatt ttacatacta   5340

ttttatgagt gttacttaat atactgatcc acagtgcgtt ttcacggtca cgccatcagt   5400

tgtaggagtg tgccaagaac agatgggcct tgcctttgta ccagaggagt ccatttacag   5460

ttgcaggtaa tagaaaaccc aattcagact ggcctaaaca atgaggggag gttttggctc   5520

ttgaaactgg aaagtcccaa ggtggggtga gtttcaggtt tgggttgatc caagtggctc   5580

agtgacgtca acaggatctt gtttccattt ctctgccttc cacagcctcc ccttcatcta   5640

tggtggaggg aaggagtcta ccacagacaa accccgagcc tccccctgat gggtggtgtg   5700

gtggtgaagc cagcaaggga agggatcccc ggacacaccc ctcctcatgc tttatcccac   5760

tgaaaccatg cggctgt                                                  5777


<210>  7138
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  7138

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Asn Gln Cys Cys Gly 
            20                  25                  30


Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser 
        35                  40                  45


Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys Cys 
    50                  55                  60


Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr Asp 
65                  70                  75                  80


Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys 
                85                  90                  95


Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile 
            100                 105                 110


Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile 
        115                 120                 125


Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala Gly 
    130                 135                 140


His His Phe 
145


<210>  7139
<211>  825
<212>  DNA
<213>  Homo sapiens

<400>  7139
aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg     60

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    120

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt ttcttctggt    180

cttggtgcta ctgaaattgt cacccagaat ttgaatcctg accctcccca ctgcaagccc    240

agggagcccc agcccaagat ggccagcctg aaactgttgg ccagggctcc tcttgtggcc    300

atgtacccag ggctggctgg cctgccattt gcctctcccc ggagacagcc gttcttctgc    360

aaccacaccc cgtgcctagc cacaacccca ggctgcagct gctcagaagc tccaggcatt    420

ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc cttcctgtca    480

gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac tcccctgggg    540

atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag ctcagaccac    600

ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt acattctagt    660

gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat tctctgtaga    720

ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac tgccaaactc    780

ttttatggaa tatatcttta tattaatgct gttttggtca ttttt                    825


<210>  7140
<211>  143
<212>  PRT
<213>  Homo sapiens

<400>  7140

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Ser 
            20                  25                  30


Ser Gly Leu Gly Ala Thr Glu Ile Val Thr Gln Asn Leu Asn Pro Asp 
        35                  40                  45


Pro Pro His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu 
    50                  55                  60


Lys Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala 
65                  70                  75                  80


Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His 
                85                  90                  95


Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro 
            100                 105                 110


Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr 
        115                 120                 125


Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
    130                 135                 140


<210>  7141
<211>  2246
<212>  DNA
<213>  Homo sapiens

<400>  7141
aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg     60

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    120

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt ttcttctggt    180

cttggtgcta ctgaaattgt cacccagaat ttgaatcctg accctcccca ctgcaagccc    240

agggagcccc agcccaagat ggccagcctg aaactgttgg ccagggctcc tcttgtggcc    300

atgtacccag ggctggctgg cctgccattt gcctctcccc ggagacagcc gttcttctgc    360

aaccacaccc cgtgcctagc cacaacccca ggctgcagct gctcagaagc tccaggcatt    420

ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc cttcctgtca    480

gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac tcccctgggg    540

atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag ctcagaccac    600

ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt acattctagt    660

gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat tctctgtaga    720

ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac tgccaaactc    780

ttttatggaa tatatcttta tattaatgct gttttggtca tttttgtttg gggtcactat    840

tgagatattg ctaagcatct cagtggtaaa cgcggctgcc agaggaacca agggataggg    900

tatgtagacc ttacagaagg atggatggta aaggcagtcc atcatcagca caatctgact    960

tacatttcat tgagtaattt tttttttttt taagattctg tatggcagca ctttcagttg   1020

cccttgtgtg ccggccacag ccgcacaagt tggcttgtgg tttatccccc gctataagtg   1080

agagctggag aaacttcaac tccataggtc tagaggaaac attgttttag gttatttctg   1140

tccacccctg tgcgatacta tttattgatc caagcagaag agcttgggga cactgagtcg   1200

aagtggggac atgggattga agcctgggca ctgctgctgc atgagctgtg tgtcctgggt   1260

gtgccggcct ttctgtgaag ggggttggtg gcagtgccca cctcactaga tgcctctgac   1320

ccagcctccc ctgggggagt gggtggccac agaccctccc tgccagagct cctggaaggc   1380

tcctgcaggc ctgacccatc tattcctgta gacctggttt aggatgaagt ctcggtgcga   1440

tttttgcaga gttgggttta tctttcaact atagaccctt ctggctgttc tcagccatat   1500

catgtgactc tgaatagttg gatgaggaat ggaaagaaag caaggatgag agccggtcac   1560

gtggcagtct ccgcccagca tcggctgtcc gcacagaggc acagggcagg cctcctgtgc   1620

actccccacc tagcactggc ctgtcctgaa tccccgcctt ccctggttgg aggccagctg   1680

tggcatttgc accctcttct cacctcacca tgcacatgct aactttaaag ccttggggtc   1740

tttcctgtac cccctcctca accctggtcc accccctctc aggatcttgt caacgttatt   1800

tttcctgtcc cgtcttccta tcgctggcct tcctttccca tcctaaaaac ttgccgaggc   1860

cctatggctc cctccctttc tttcccaggc agcttcttat ctgggctgtc tgtacccctt   1920

cctttgcacc acccaccatg ccccacgtag ctgaaagctg cttatcccaa ttgtcaactc   1980

tggccttctt cagcctctgt agcaccagac actgcacctc ctgaatgtcc tctgcttctc   2040

tgcttcagag gcccaggctc gccagttctc tgacctctcc catatgtctg cttaggactc   2100

tgctgcagct gtcctcacca gcctccgggg aatcccacta cccacagggc agggctgtgg   2160

gctgggctga aaaaccatct gcatggtcca caagaagcct ggcactgggt ttccccatga   2220

ataacaatga aaattaatgg atgcac                                        2246


<210>  7142
<211>  143
<212>  PRT
<213>  Homo sapiens

<400>  7142

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Ser 
            20                  25                  30


Ser Gly Leu Gly Ala Thr Glu Ile Val Thr Gln Asn Leu Asn Pro Asp 
        35                  40                  45


Pro Pro His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu 
    50                  55                  60


Lys Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala 
65                  70                  75                  80


Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His 
                85                  90                  95


Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro 
            100                 105                 110


Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr 
        115                 120                 125


Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
    130                 135                 140


<210>  7143
<211>  2865
<212>  DNA
<213>  Homo sapiens

<400>  7143
aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg     60

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    120

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt tgtcttcctt    180

ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt ccgacctcac caaagtgacc    240

cggatgcatg gaatcgaccc tgtggtgctg gtccaccccc tctcaggatc ttgtcaacgt    300

tatttttcct gtcccgtctt cctatcgctg gccttccttt cccatcctaa aaacttgccg    360

aggccctatg gctccctccc tttctttccc aggcagcttc ttatctgggc tgtctgtacc    420

ccttcctttg caccacccac catgccccac gtagctgaaa gctgcttatc ccaattgtca    480

actctggcct tcttcagcct ctgtagcacc agacactgca cctcctgaat gtcctctgct    540

tctctgcttc agaggcccag gctcgccagt tctctgacct ctcccatatg tctgcttagg    600

actctgctgc agctgtcctc accagcctcc ggggaatccc actacccaca gggcagggct    660

gtgggctggg ctgaaaaacc atctgcatgg tccacaagaa gcctggcact gggtttcccc    720

atgaataaca atgaaaatta atggatgcac aaccttcctg gaacgtggaa tttctctggg    780

agattccatg cagaggccac tggggaggtg gcaggcatgc atgtgactgt aggtggctgc    840

agtgttggaa ggctcccagc agagcagaga gggtgtcagt ctcatcaggg aacccacctg    900

atggcttctc agccagcagt ctcagaggaa catagacgac tgctgagaaa ggagggaggc    960

agcagtggtc ccagcacctg aggcatcctg ctgtcatggg aaggtctccg cccaaatgtc   1020

agatgcatca gcctgtcacc cgctggtcca gagctttcag ctgtactggt agggggtggg   1080

tggtggagtg ctgaatgacc ttcacaggtg ggcctttcca gctctagggt cttacgggtg   1140

tcggtccaca gaaccacggt ttttaggttg tgtgtccggg gctatgggaa cctgtccccc   1200

atgatggatc ttggtagaga cacttccctc tgtcatcgtg cccaggagga tgctgcaggt   1260

gactacctgc agccctgttc tcattcattt ggatgccctc cagaaatctg gggagccata   1320

cacctttaga gccttttttg ctccttatca agttggcaag gcttggccaa ttcctgttca   1380

aggctgcatt aaaggcatgt tcaccatcct ggctaatacg gtgaaacccc ttctctacta   1440

aaaatacaaa aaaattagcc gggcttggtg gcgggtgcct gtagtcccag ctactccgga   1500

ggctgaggca ggggaatggt gtgaacccag gaggcggagc ttgcagtgag ccgagatcac   1560

accactgcac tccagcctgg gctcaaaaaa gaaaaaaaaa aaaaaaaaaa ggcccgttca   1620

ttctcaaatg cttttggcgt ctccagggtg cctcaggaaa acatgaagtg ggcattgtag   1680

aacttggggc tactgtgtaa ctttggaaga aaaagttaag ggtactttta agtggatact   1740

gttttgatga aattgccaac ttcagggagc ccagcttgga gaaggaggac gtgagtattc   1800

cttacaaggc tccgaaacaa ttctttcttc acttagtttt ctttctgtgc tctgcatctt   1860

atattccagc agggtcttcc aatgcatggt ttaataacta ctagaactgg ccaggtgcag   1920

tggctcacgc ctgtaatccc agaactttgg gaggctaaga caggcagatc acttgaggcc   1980

aggagttcga gaccagcctg gacaacatgg tgatacccag tttctactaa aaatacaaaa   2040

attagtcggg catggtgatg tgcacctgta gtcccagctg ctcgggaggc tgaggcagga   2100

gaatcgcttg aacccgggag acagaggttg caacgagcca agatcgagcc actgcgctcc   2160

ggcctgggtg acaggagact ccatctcaaa aaataaaatt aaaaaaaaac tactacaata   2220

aattatcacc ttggactgta taaaacaact tttaaactag tctttttaaa aagtacactt   2280

aaataaaaat ctaaacataa gagaatgtaa agtgaaaagt gaaagtatgt cttctgttac   2340

gcagaggtaa ctactattag gaatccttcc tgaaaatgtc catgcatcta ctcaggtcat   2400

cacacccatg gaatcatttt acatactatt ttatgagtgt tacttaatat actgatccac   2460

agtgcgtttt cacggtcacg ccatcagttg taggagtgtg ccaagaacag atgggccttg   2520

cctttgtacc agaggagtcc atttacagtt gcaggtaata gaaaacccaa ttcagactgg   2580

cctaaacaat gaggggaggt tttggctctt gaaactggaa agtcccaagg tggggtgagt   2640

ttcaggtttg ggttgatcca agtggctcag tgacgtcaac aggatcttgt ttccatttct   2700

ctgccttcca cagcctcccc ttcatctatg gtggagggaa ggagtctacc acagacaaac   2760

cccgagcctc cccctgatgg gtggtgtggt ggtgaagcca gcaagggaag ggatccccgg   2820

acacacccct cctcatgctt tatcccactg aaaccatgcg gctgt                   2865


<210>  7144
<211>  149
<212>  PRT
<213>  Homo sapiens

<400>  7144

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser Cys Pro Val 
65                  70                  75                  80


Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu Pro Arg Pro 
                85                  90                  95


Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile Trp Ala Val 
            100                 105                 110


Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val Ala Glu Ser 
        115                 120                 125


Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu Cys Ser Thr 
    130                 135                 140


Arg His Cys Thr Ser 
145


<210>  7145
<211>  4361
<212>  DNA
<213>  Homo sapiens

<400>  7145
aacttgctct aacttcctcg gccgagccgg gccgcgccgc cgctgccgcc gccgcgcgcg     60

gattctgctt ctcagaagat gcactattat agatactcta acgccaaggt cagctgctgg    120

tacaagtacc tccttttcag ctacaacatc atcttctggt tggctggagt ttcttctggt    180

cttggtgcta ctgaaattgt cacccagaat ttgaatcctg accctcccca ctgcaagccc    240

agggagcccc agcccaagat ggccagcctg aaactgttgg ccagggctcc tcttgtggcc    300

atgtacccag ggctggctgg cctgccattt gcctctcccc ggagacagcc gttcttctgc    360

aaccacaccc cgtgcctagc cacaacccca ggctgcagct gctcagaagc tccaggcatt    420

ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc cttcctgtca    480

gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac tcccctgggg    540

atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag ctcagaccac    600

ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt acattctagt    660

gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat tctctgtaga    720

ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac tgccaaactc    780

ttttatggaa tatatcttta tattaatgct gttttggtca tttttgtttg gggtcactat    840

tgagatattg ctaagcatct cagtggtaaa cgcggctgcc agaggaacca agggataggg    900

tatgtagacc ttacagaagg atggatggta aaggcagtcc atcatcagca caatctgact    960

tacatttcat tgagtaattt tttttttttt taagattctg tatggcagca ctttcagttg   1020

cccttgtgtg ccggccacag ccgcacaagt tggcttgtgg tttatccccc gctataagtg   1080

agagctggag aaacttcaac tccataggtc tagaggaaac attgttttag gttatttctg   1140

tccacccctg tgcgatacta tttattgatc caagcagaag agcttgggga cactgagtcg   1200

aagtggggac atgggattga agcctgggca ctgctgctgc atgagctgtg tgtcctgggt   1260

gtgccggcct ttctgtgaag ggggttggtg gcagtgccca cctcactaga tgcctctgac   1320

ccagcctccc ctgggggagt gggtggccac agaccctccc tgccagagct cctggaaggc   1380

tcctgcaggc ctgacccatc tattcctgta gacctggttt aggatgaagt ctcggtgcga   1440

tttttgcaga gttgggttta tctttcaact atagaccctt ctggctgttc tcagccatat   1500

catgtgactc tgaatagttg gatgaggaat ggaaagaaag caaggatgag agccggtcac   1560

gtggcagtct ccgcccagca tcggctgtcc gcacagaggc acagggcagg cctcctgtgc   1620

actccccacc tagcactggc ctgtcctgaa tccccgcctt ccctggttgg aggccagctg   1680

tggcatttgc accctcttct cacctcacca tgcacatgct aactttaaag ccttggggtc   1740

tttcctgtac cccctcctca accctggtcc accccctctc aggatcttgt caacgttatt   1800

tttcctgtcc cgtcttccta tcgctggcct tcctttccca tcctaaaaac ttgccgaggc   1860

cctatggctc cctccctttc tttcccaggc agcttcttat ctgggctgtc tgtacccctt   1920

cctttgcacc acccaccatg ccccacgtag ctgaaagctg cttatcccaa ttgtcaactc   1980

tggccttctt cagcctctgt agcaccagac actgcacctc ctgaatgtcc tctgcttctc   2040

tgcttcagag gcccaggctc gccagttctc tgacctctcc catatgtctg cttaggactc   2100

tgctgcagct gtcctcacca gcctccgggg aatcccacta cccacagggc agggctgtgg   2160

gctgggctga aaaaccatct gcatggtcca caagaagcct ggcactgggt ttccccatga   2220

ataacaatga aaattaatgg atgcacaacc ttcctggaac gtggaatttc tctgggagat   2280

tccatgcaga ggccactggg gaggtggcag gcatgcatgt gactgtaggt ggctgcagtg   2340

ttggaaggct cccagcagag cagagagggt gtcagtctca tcagggaacc cacctgatgg   2400

cttctcagcc agcagtctca gaggaacata gacgactgct gagaaaggag ggaggcagca   2460

gtggtcccag cacctgaggc atcctgctgt catgggaagg tctccgccca aatgtcagat   2520

gcatcagcct gtcacccgct ggtccagagc tttcagctgt actggtaggg ggtgggtggt   2580

ggagtgctga atgaccttca caggtgggcc tttccagctc tagggtctta cgggtgtcgg   2640

tccacagaac cacggttttt aggttgtgtg tccggggcta tgggaacctg tcccccatga   2700

tggatcttgg tagagacact tccctctgtc atcgtgccca ggaggatgct gcaggtgact   2760

acctgcagcc ctgttctcat tcatttggat gccctccaga aatctgggga gccatacacc   2820

tttagagcct tttttgctcc ttatcaagtt ggcaaggctt ggccaattcc tgttcaaggc   2880

tgcattaaag gcatgttcac catcctggct aatacggtga aaccccttct ctactaaaaa   2940

tacaaaaaaa ttagccgggc ttggtggcgg gtgcctgtag tcccagctac tccggaggct   3000

gaggcagggg aatggtgtga acccaggagg cggagcttgc agtgagccga gatcacacca   3060

ctgcactcca gcctgggctc aaaaaagaaa aaaaaaaaaa aaaaaaggcc cgttcattct   3120

caaatgcttt tggcgtctcc agggtgcctc aggaaaacat gaagtgggca ttgtagaact   3180

tggggctact gtgtaacttt ggaagaaaaa gttaagggta cttttaagtg gatactgttt   3240

tgatgaaatt gccaacttca gggagcccag cttggagaag gaggacgtga gtattcctta   3300

caaggctccg aaacaattct ttcttcactt agttttcttt ctgtgctctg catcttatat   3360

tccagcaggg tcttccaatg catggtttaa taactactag aactggccag gtgcagtggc   3420

tcacgcctgt aatcccagaa ctttgggagg ctaagacagg cagatcactt gaggccagga   3480

gttcgagacc agcctggaca acatggtgat acccagtttc tactaaaaat acaaaaatta   3540

gtcgggcatg gtgatgtgca cctgtagtcc cagctgctcg ggaggctgag gcaggagaat   3600

cgcttgaacc cgggagacag aggttgcaac gagccaagat cgagccactg cgctccggcc   3660

tgggtgacag gagactccat ctcaaaaaat aaaattaaaa aaaaactact acaataaatt   3720

atcaccttgg actgtataaa acaactttta aactagtctt tttaaaaagt acacttaaat   3780

aaaaatctaa acataagaga atgtaaagtg aaaagtgaaa gtatgtcttc tgttacgcag   3840

aggtaactac tattaggaat ccttcctgaa aatgtccatg catctactca ggtcatcaca   3900

cccatggaat cattttacat actattttat gagtgttact taatatactg atccacagtg   3960

cgttttcacg gtcacgccat cagttgtagg agtgtgccaa gaacagatgg gccttgcctt   4020

tgtaccagag gagtccattt acagttgcag gtaatagaaa acccaattca gactggccta   4080

aacaatgagg ggaggttttg gctcttgaaa ctggaaagtc ccaaggtggg gtgagtttca   4140

ggtttgggtt gatccaagtg gctcagtgac gtcaacagga tcttgtttcc atttctctgc   4200

cttccacagc ctccccttca tctatggtgg agggaaggag tctaccacag acaaaccccg   4260

agcctccccc tgatgggtgg tgtggtggtg aagccagcaa gggaagggat ccccggacac   4320

acccctcctc atgctttatc ccactgaaac catgcggctg t                       4361


<210>  7146
<211>  143
<212>  PRT
<213>  Homo sapiens

<400>  7146

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Ser 
            20                  25                  30


Ser Gly Leu Gly Ala Thr Glu Ile Val Thr Gln Asn Leu Asn Pro Asp 
        35                  40                  45


Pro Pro His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu 
    50                  55                  60


Lys Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala 
65                  70                  75                  80


Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His 
                85                  90                  95


Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro 
            100                 105                 110


Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr 
        115                 120                 125


Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
    130                 135                 140


<210>  7147
<211>  1644
<212>  DNA
<213>  Homo sapiens

<400>  7147
acttgctcta acttcctcgg ccgagccggg ccgcgccgcc gctgccgccg ccgcgcgcgg     60

cgttacatcc ttactattca aagtgccatc cacagacctg ctgatgggca gcatgagcat    120

cacctgggag cttgctgcgc tgtagaatct tgaggggtct ccatccagat cagctgaatc    180

agagtttgca ttgttaacaa gattctgctt ctcagaagat gcactattat agatactcta    240

acgccaaggt cagctgctgg tacaagtacc tccttttcag ctacaacatc atcttctggt    300

tggctggagt tgtcttcctt ggagtcgggc tgtgggcatg gagcgaaaag ggtgtgctgt    360

ccgacctcac caaagtgacc cggatgcatg gaatcgaccc tgtggtgctg gtcctgatgg    420

tgggcgtggt gatgttcacc ctggggttcg ccggctgcgt gggggctctg cgggagaata    480

tctgcttgct caactttttc tgtggcacca tcgtgctcat cttcttcctg gagctggctg    540

tggccgtgct ggccttcctg ttccaggact gggtgaggga ccggttccgg gagttcttcg    600

agagcaacat caagtcctac cgggacgata tcgatctgca aaacctcatc gactcccttc    660

agaaagctgt aagcacctcc ccagcgggcc cccgatagag catgcacctc cctgtgctgc    720

ctggagctga gtctagcagg ggcatcaggc cttctctgtg ggttgtctgc ctgcagcttg    780

gcagacagca gggaggccgt ggaacaagcc actccacctc tggtctgttc cactttgccg    840

gcttgtggtt gcctggtggg ccagcccttt cccattggga ttgggcaggc aagtccagct    900

gtacccgagg ccacccaccc cccacgtgcc cggccctcct ctttcggccc cagatctttc    960

caatcctgcc caatagccat accagctgca atcctcctta ggcgctgcat accgtaaggc   1020

acagcttctt ccccccggct catgactcac catctgacgc tattcctatc cccttcctcc   1080

ccgggacctt ttccccttcc tccctgggac cttttcccct tcctgtttaa gaagccaggg   1140

ctgcctggag gaagctttgt cagatctagt ggaatgtgac ctccctggaa tatgtgccca   1200

ggggtttgtc taagcagttc caggctatgg cctttactcc atctggtccc catccctctt   1260

atctctctca tgtgtggctg cacctggacg cttggaccat agctgtcaca gccccctggg   1320

gaggaaccca ctccttggcc atgtcagcct gtgcaatgca aggctcttgt ttgatctgtg   1380

tgctgacaga aagcccagct tccttaagaa cttttcatgt ggaacacttt ggttttgaga   1440

agaaaataaa tcagaaacca ttaaaaatct atgattcact ctcattatta accaaaactt   1500

gttcaccttt atttcatgta ttatgggatc cagcaaaacc catttatggg accaaagacc   1560

ctgcctgtat tgttattact aatgtgtatt agtctgtgaa agtcaccaaa tccccgccat   1620

gttttgatgc ctctcctttc tttt                                          1644


<210>  7148
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  7148

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Val Ser Thr Ser Pro Ala Gly Pro Arg 
145                 150                 155


<210>  7149
<211>  1488
<212>  DNA
<213>  Homo sapiens

<400>  7149
ctcggccgag ccgggccgcg ccgccgctgc cgccgccgcg cgcggattct gcttctcaga     60

agatgcacta ttatagatac tctaacgcca aggtcagctg ctggtacaag tacctccttt    120

tcagctacaa catcatcttc tggttggctg gagttgtctt ccttggagtc gggctgtggg    180

catggagcga aaagggtgtg ctgtccgacc tcaccaaagt gacccggatg catggaatcg    240

accctgtggt gctggtcctg atggtgggcg tggtgatgtt caccctgggg ttcgccggct    300

gcgtgggggc tctgcgggag aatatctgct tgctcaactt tttctgtggc accatcgtgc    360

tcatcttctt cctggagctg gctgtggccg tgctggcctt cctgttccag gactgggtga    420

gggaccggtt ccgggagttc ttcgagagca acatcaagtc ctaccgggac gatatcgatc    480

tgcaaaacct catcgactcc cttcagaaag ctgtaagcac ctccccagcg ggcccccgat    540

agagcatgca cctccctgtg ctgcctggag ctgagtctag caggggcatc aggccttctc    600

tgtgggttgt ctgcctgcag cttggcagac agcagggagg ccgtggaaca agccactcca    660

cctctggtct gttccacttt gccggcttgt ggttgcctgg tgggccagcc ctttcccatt    720

gggattgggc aggcaagtcc agctgtaccc gaggccaccc accccccacg tgcccggccc    780

tcctctttcg gccccagatc tttccaatcc tgcccaatag ccataccagc tgcaatcctc    840

cttaggcgct gcataccgta aggcacagct tcttcccccc ggctcatgac tcaccatctg    900

acgctattcc tatccccttc ctccccggga ccttttcccc ttcctccctg ggaccttttc    960

cccttcctgt ttaagaagcc agggctgcct ggaggaagct ttgtcagatc tagtggaatg   1020

tgacctccct ggaatatgtg cccaggggtt tgtctaagca gttccaggct atggccttta   1080

ctccatctgg tccccatccc tcttatctct ctcatgtgtg gctgcacctg gacgcttgga   1140

ccatagctgt cacagccccc tggggaggaa cccactcctt ggccatgtca gcctgtgcaa   1200

tgcaaggctc ttgtttgatc tgtgtgctga cagaaagccc agcttcctta agaacttttc   1260

atgtggaaca ctttggtttt gagaagaaaa taaatcagaa accattaaaa atctatgatt   1320

cactctcatt attaaccaaa acttgttcac ctttatttca tgtattatgg gatccagcaa   1380

aacccattta tgggaccaaa gaccctgcct gtattgttat tactaatgtg tattagtctg   1440

tgaaagtcac caaatccccg ccatgttttg atgcctctcc tttctttt                1488


<210>  7150
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  7150

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu 
    50                  55                  60


Val Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys 
65                  70                  75                  80


Val Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly 
                85                  90                  95


Thr Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala 
            100                 105                 110


Phe Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu 
        115                 120                 125


Ser Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile 
    130                 135                 140


Asp Ser Leu Gln Lys Ala Val Ser Thr Ser Pro Ala Gly Pro Arg 
145                 150                 155


<210>  7151
<211>  2230
<212>  DNA
<213>  Homo sapiens

<400>  7151
ctcggccgag ccgggccgcg ccgccgctgc cgccgccgcg cgcggattct gcttctcaga     60

agatgcacta ttatagatac tctaacgcca aggtcagctg ctggtacaag tacctccttt    120

tcagctacaa catcatcttc tggttggctg gagttgtctt ccttggagtc gggctgtggg    180

catggagcga aaagaaccag tgctgtggcg catatggccc tgaagactgg gacctcaacg    240

tctacttcaa ttgcagcggt gccagctaca gccgagagaa gtgcggggtc cccttctcct    300

gctgcgtgcc agatcctgcg caaaaagttg tgaacacaca gtgtggatat gatgtcagga    360

ttcagctgaa gagcaagtgg gatgagtcca tcttcacgaa aggctgcatc caggcgctgg    420

aaagctggct cccgcggaac atttacattg tggctggcgt cttcatcgcc atctcgctgt    480

tgcagatatt tggcatcttc ctggcaagga cgctgatctc agacatcgag gcagtgaagg    540

ccggccatca cttctgagga gcagagttga gggagccgag ctgagccacg ctgggaggcc    600

agagcctttc tctgccatca gccctacgtc cagagggaga ggagccgaca cccccagagc    660

cagtgcccca tcttaagcat cagcgtgacg tgacctctct gtttctgctt gctggtgctg    720

aagaccaagg gtcccccttg ttacctgccc aaacttgtga ctgcatccct ctggagtcta    780

cccagagaca gagaatgtgt ctttatgtgg gagtggtgac tctgaaagac agagagggct    840

cctgtggctg ccaggagggc ttgactcaga ccccctgcag ctcaagcatg tctgcaggac    900

accctggtcc cctctccact ggcatccaga catctgcttt gggtcatcca catctgtggg    960

tgggccgtgg gtagagggac ccacaggcgt ggacagggca tctctctcca tcaagcaaag   1020

cagcatgggg gcctgcccgt aacgggaggc ggacgtggcc ccgctgggcc tctgagtgcc   1080

agcgcagtct gctgggacat gcacatatca ggggttgttt gcaggatcct cagccatgtt   1140

caagtgaagt aagcctgagc cagtgcgtgg actggtgcca cgggagtgcc ttgtccactg   1200

tccccctgtg tccaccagct attctcctgg cgccggaact gcctctggtc ttgatagcat   1260

taagccctga tggcgccggt ggcgcggtgg gcatggttct tcactgagag ccggctctcc   1320

ttttcttaaa gtgtgtaaat agtttattta taggggtaag aatgttctca caccatttca   1380

cttcctcttc ctctcctcca gcattctcct ctgagcagcc ttagatagtg tccatggctg   1440

gagccgaccc tttgagtccc cttgagtgtc ttaagaacca gcccacaaca gcctctcttt   1500

ctcctccaca tactgcagcc tccctccatg catcccacat acaagcactc ccccactccc   1560

cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa attgtcaccc agaatttgaa   1620

tcctgaccct ccccactgca agcccaggga gccccagccc aagatggcca gcctgaaact   1680

gttggccagg gctcctcttg tggccatgta cccagggctg gctggcctgc catttgcctc   1740

tccccggaga cagccgttct tctgcaacca caccccgtgc ctagccacaa ccccaggctg   1800

cagctgctca gaagctccag gcattttgtt tctggtgacc gcccctaatg ggatatcggt   1860

gatcactggt ccacccttcc tgtcagggct tttctggggc tgctcttgga aatgaagtct   1920

taagtactga ataactcccc tggggatagc tggggcattt gtctagctgg gctactttct   1980

aacactttgc catagctcag accacttctc atcgttcagg gatggactgc aaccttaatt   2040

tacttgccgg agtgtacatt ctagtgtggt gtatactggt ggctgttgat gatgattttt   2100

ttttttttac acaattctct gtagactagg agaagaatgc ttgtgttttt cggaagtgtg   2160

atgcttctct ttgactgcca aactctttta tggaatatat ctttatatta atgctgtttt   2220

ggtcattttt                                                          2230


<210>  7152
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  7152

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Asn Gln Cys Cys 
        35                  40                  45


Gly Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys 
    50                  55                  60


Ser Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys 
65                  70                  75                  80


Cys Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr 
                85                  90                  95


Asp Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr 
            100                 105                 110


Lys Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr 
        115                 120                 125


Ile Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly 
    130                 135                 140


Ile Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala 
145                 150                 155                 160


Gly His His Phe 



<210>  7153
<211>  3651
<212>  DNA
<213>  Homo sapiens

<400>  7153
ctcggccgag ccgggccgcg ccgccgctgc cgccgccgcg cgcggattct gcttctcaga     60

agatgcacta ttatagatac tctaacgcca aggtcagctg ctggtacaag tacctccttt    120

tcagctacaa catcatcttc tggttggctg gagttgtctt ccttggagtc gggctgtggg    180

catggagcga aaagaaccag tgctgtggcg catatggccc tgaagactgg gacctcaacg    240

tctacttcaa ttgcagcggt gccagctaca gccgagagaa gtgcggggtc cccttctcct    300

gctgcgtgcc agatcctgcg caaaaagttg tgaacacaca gtgtggatat gatgtcagga    360

ttcagctgaa gagcaagtgg gatgagtcca tcttcacgaa aggctgcatc caggcgctgg    420

aaagctggct cccgcggaac atttacattg tggctggcgt cttcatcgcc atctcgctgt    480

tgcagatatt tggcatcttc ctggcaagga cgctgatctc agacatcgag gcagtgaagg    540

ccggccatca cttctgagga gcagagttga gggagccgag ctgagccacg ctgggaggcc    600

agagcctttc tctgccatca gccctacgtc cagagggaga ggagccgaca cccccagagc    660

cagtgcccca tcttaagcat cagcgtgacg tgacctctct gtttctgctt gctggtgctg    720

aagaccaagg gtcccccttg ttacctgccc aaacttgtga ctgcatccct ctggagtcta    780

cccagagaca gagaatgtgt ctttatgtgg gagtggtgac tctgaaagac agagagggct    840

cctgtggctg ccaggagggc ttgactcaga ccccctgcag ctcaagcatg tctgcaggac    900

accctggtcc cctctccact ggcatccaga catctgcttt gggtcatcca catctgtggg    960

tgggccgtgg gtagagggac ccacaggcgt ggacagggca tctctctcca tcaagcaaag   1020

cagcatgggg gcctgcccgt aacgggaggc ggacgtggcc ccgctgggcc tctgagtgcc   1080

agcgcagtct gctgggacat gcacatatca ggggttgttt gcaggatcct cagccatgtt   1140

caagtgaagt aagcctgagc cagtgcgtgg actggtgcca cgggagtgcc ttgtccactg   1200

tccccctgtg tccaccagct attctcctgg cgccggaact gcctctggtc ttgatagcat   1260

taagccctga tggcgccggt ggcgcggtgg gcatggttct tcactgagag ccggctctcc   1320

ttttcttaaa gtgtgtaaat agtttattta taggggtaag aatgttctca caccatttca   1380

cttcctcttc ctctcctcca gcattctcct ctgagcagcc ttagatagtg tccatggctg   1440

gagccgaccc tttgagtccc cttgagtgtc ttaagaacca gcccacaaca gcctctcttt   1500

ctcctccaca tactgcagcc tccctccatg catcccacat acaagcactc ccccactccc   1560

cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa attgtcaccc agaatttgaa   1620

tcctgaccct ccccactgca agcccaggga gccccagccc aagatggcca gcctgaaact   1680

gttggccagg gctcctcttg tggccatgta cccagggctg gctggcctgc catttgcctc   1740

tccccggaga cagccgttct tctgcaacca caccccgtgc ctagccacaa ccccaggctg   1800

cagctgctca gaagctccag gcattttgtt tctggtgacc gcccctaatg ggatatcggt   1860

gatcactggt ccacccttcc tgtcagggct tttctggggc tgctcttgga aatgaagtct   1920

taagtactga ataactcccc tggggatagc tggggcattt gtctagctgg gctactttct   1980

aacactttgc catagctcag accacttctc atcgttcagg gatggactgc aaccttaatt   2040

tacttgccgg agtgtacatt ctagtgtggt gtatactggt ggctgttgat gatgattttt   2100

ttttttttac acaattctct gtagactagg agaagaatgc ttgtgttttt cggaagtgtg   2160

atgcttctct ttgactgcca aactctttta tggaatatat ctttatatta atgctgtttt   2220

ggtcattttt gtttggggtc actattgaga tattgctaag catctcagtg gtaaacgcgg   2280

ctgccagagg aaccaaggga tagggtatgt agaccttaca gaaggatgga tggtaaaggc   2340

agtccatcat cagcacaatc tgacttacat ttcattgagt aatttttttt ttttttaaga   2400

ttctgtatgg cagcactttc agttgccctt gtgtgccggc cacagccgca caagttggct   2460

tgtggtttat cccccgctat aagtgagagc tggagaaact tcaactccat aggtctagag   2520

gaaacattgt tttaggttat ttctgtccac ccctgtgcga tactatttat tgatccaagc   2580

agaagagctt ggggacactg agtcgaagtg gggacatggg attgaagcct gggcactgct   2640

gctgcatgag ctgtgtgtcc tgggtgtgcc ggcctttctg tgaagggggt tggtggcagt   2700

gcccacctca ctagatgcct ctgacccagc ctcccctggg ggagtgggtg gccacagacc   2760

ctccctgcca gagctcctgg aaggctcctg caggcctgac ccatctattc ctgtagacct   2820

ggtttaggat gaagtctcgg tgcgattttt gcagagttgg gtttatcttt caactataga   2880

cccttctggc tgttctcagc catatcatgt gactctgaat agttggatga ggaatggaaa   2940

gaaagcaagg atgagagccg gtcacgtggc agtctccgcc cagcatcggc tgtccgcaca   3000

gaggcacagg gcaggcctcc tgtgcactcc ccacctagca ctggcctgtc ctgaatcccc   3060

gccttccctg gttggaggcc agctgtggca tttgcaccct cttctcacct caccatgcac   3120

atgctaactt taaagccttg gggtctttcc tgtaccccct cctcaaccct ggtccacccc   3180

ctctcaggat cttgtcaacg ttatttttcc tgtcccgtct tcctatcgct ggccttcctt   3240

tcccatccta aaaacttgcc gaggccctat ggctccctcc ctttctttcc caggcagctt   3300

cttatctggg ctgtctgtac cccttccttt gcaccaccca ccatgcccca cgtagctgaa   3360

agctgcttat cccaattgtc aactctggcc ttcttcagcc tctgtagcac cagacactgc   3420

acctcctgaa tgtcctctgc ttctctgctt cagaggccca ggctcgccag ttctctgacc   3480

tctcccatat gtctgcttag gactctgctg cagctgtcct caccagcctc cggggaatcc   3540

cactacccac agggcagggc tgtgggctgg gctgaaaaac catctgcatg gtccacaaga   3600

agcctggcac tgggtttccc catgaataac aatgaaaatt aatggatgca c            3651


<210>  7154
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  7154

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Asn Gln Cys Cys 
        35                  40                  45


Gly Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys 
    50                  55                  60


Ser Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys 
65                  70                  75                  80


Cys Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr 
                85                  90                  95


Asp Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr 
            100                 105                 110


Lys Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr 
        115                 120                 125


Ile Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly 
    130                 135                 140


Ile Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala 
145                 150                 155                 160


Gly His His Phe 



<210>  7155
<211>  5766
<212>  DNA
<213>  Homo sapiens

<400>  7155
ctcggccgag ccgggccgcg ccgccgctgc cgccgccgcg cgcggattct gcttctcaga     60

agatgcacta ttatagatac tctaacgcca aggtcagctg ctggtacaag tacctccttt    120

tcagctacaa catcatcttc tggttggctg gagttgtctt ccttggagtc gggctgtggg    180

catggagcga aaagaaccag tgctgtggcg catatggccc tgaagactgg gacctcaacg    240

tctacttcaa ttgcagcggt gccagctaca gccgagagaa gtgcggggtc cccttctcct    300

gctgcgtgcc agatcctgcg caaaaagttg tgaacacaca gtgtggatat gatgtcagga    360

ttcagctgaa gagcaagtgg gatgagtcca tcttcacgaa aggctgcatc caggcgctgg    420

aaagctggct cccgcggaac atttacattg tggctggcgt cttcatcgcc atctcgctgt    480

tgcagatatt tggcatcttc ctggcaagga cgctgatctc agacatcgag gcagtgaagg    540

ccggccatca cttctgagga gcagagttga gggagccgag ctgagccacg ctgggaggcc    600

agagcctttc tctgccatca gccctacgtc cagagggaga ggagccgaca cccccagagc    660

cagtgcccca tcttaagcat cagcgtgacg tgacctctct gtttctgctt gctggtgctg    720

aagaccaagg gtcccccttg ttacctgccc aaacttgtga ctgcatccct ctggagtcta    780

cccagagaca gagaatgtgt ctttatgtgg gagtggtgac tctgaaagac agagagggct    840

cctgtggctg ccaggagggc ttgactcaga ccccctgcag ctcaagcatg tctgcaggac    900

accctggtcc cctctccact ggcatccaga catctgcttt gggtcatcca catctgtggg    960

tgggccgtgg gtagagggac ccacaggcgt ggacagggca tctctctcca tcaagcaaag   1020

cagcatgggg gcctgcccgt aacgggaggc ggacgtggcc ccgctgggcc tctgagtgcc   1080

agcgcagtct gctgggacat gcacatatca ggggttgttt gcaggatcct cagccatgtt   1140

caagtgaagt aagcctgagc cagtgcgtgg actggtgcca cgggagtgcc ttgtccactg   1200

tccccctgtg tccaccagct attctcctgg cgccggaact gcctctggtc ttgatagcat   1260

taagccctga tggcgccggt ggcgcggtgg gcatggttct tcactgagag ccggctctcc   1320

ttttcttaaa gtgtgtaaat agtttattta taggggtaag aatgttctca caccatttca   1380

cttcctcttc ctctcctcca gcattctcct ctgagcagcc ttagatagtg tccatggctg   1440

gagccgaccc tttgagtccc cttgagtgtc ttaagaacca gcccacaaca gcctctcttt   1500

ctcctccaca tactgcagcc tccctccatg catcccacat acaagcactc ccccactccc   1560

cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa attgtcaccc agaatttgaa   1620

tcctgaccct ccccactgca agcccaggga gccccagccc aagatggcca gcctgaaact   1680

gttggccagg gctcctcttg tggccatgta cccagggctg gctggcctgc catttgcctc   1740

tccccggaga cagccgttct tctgcaacca caccccgtgc ctagccacaa ccccaggctg   1800

cagctgctca gaagctccag gcattttgtt tctggtgacc gcccctaatg ggatatcggt   1860

gatcactggt ccacccttcc tgtcagggct tttctggggc tgctcttgga aatgaagtct   1920

taagtactga ataactcccc tggggatagc tggggcattt gtctagctgg gctactttct   1980

aacactttgc catagctcag accacttctc atcgttcagg gatggactgc aaccttaatt   2040

tacttgccgg agtgtacatt ctagtgtggt gtatactggt ggctgttgat gatgattttt   2100

ttttttttac acaattctct gtagactagg agaagaatgc ttgtgttttt cggaagtgtg   2160

atgcttctct ttgactgcca aactctttta tggaatatat ctttatatta atgctgtttt   2220

ggtcattttt gtttggggtc actattgaga tattgctaag catctcagtg gtaaacgcgg   2280

ctgccagagg aaccaaggga tagggtatgt agaccttaca gaaggatgga tggtaaaggc   2340

agtccatcat cagcacaatc tgacttacat ttcattgagt aatttttttt ttttttaaga   2400

ttctgtatgg cagcactttc agttgccctt gtgtgccggc cacagccgca caagttggct   2460

tgtggtttat cccccgctat aagtgagagc tggagaaact tcaactccat aggtctagag   2520

gaaacattgt tttaggttat ttctgtccac ccctgtgcga tactatttat tgatccaagc   2580

agaagagctt ggggacactg agtcgaagtg gggacatggg attgaagcct gggcactgct   2640

gctgcatgag ctgtgtgtcc tgggtgtgcc ggcctttctg tgaagggggt tggtggcagt   2700

gcccacctca ctagatgcct ctgacccagc ctcccctggg ggagtgggtg gccacagacc   2760

ctccctgcca gagctcctgg aaggctcctg caggcctgac ccatctattc ctgtagacct   2820

ggtttaggat gaagtctcgg tgcgattttt gcagagttgg gtttatcttt caactataga   2880

cccttctggc tgttctcagc catatcatgt gactctgaat agttggatga ggaatggaaa   2940

gaaagcaagg atgagagccg gtcacgtggc agtctccgcc cagcatcggc tgtccgcaca   3000

gaggcacagg gcaggcctcc tgtgcactcc ccacctagca ctggcctgtc ctgaatcccc   3060

gccttccctg gttggaggcc agctgtggca tttgcaccct cttctcacct caccatgcac   3120

atgctaactt taaagccttg gggtctttcc tgtaccccct cctcaaccct ggtccacccc   3180

ctctcaggat cttgtcaacg ttatttttcc tgtcccgtct tcctatcgct ggccttcctt   3240

tcccatccta aaaacttgcc gaggccctat ggctccctcc ctttctttcc caggcagctt   3300

cttatctggg ctgtctgtac cccttccttt gcaccaccca ccatgcccca cgtagctgaa   3360

agctgcttat cccaattgtc aactctggcc ttcttcagcc tctgtagcac cagacactgc   3420

acctcctgaa tgtcctctgc ttctctgctt cagaggccca ggctcgccag ttctctgacc   3480

tctcccatat gtctgcttag gactctgctg cagctgtcct caccagcctc cggggaatcc   3540

cactacccac agggcagggc tgtgggctgg gctgaaaaac catctgcatg gtccacaaga   3600

agcctggcac tgggtttccc catgaataac aatgaaaatt aatggatgca caaccttcct   3660

ggaacgtgga atttctctgg gagattccat gcagaggcca ctggggaggt ggcaggcatg   3720

catgtgactg taggtggctg cagtgttgga aggctcccag cagagcagag agggtgtcag   3780

tctcatcagg gaacccacct gatggcttct cagccagcag tctcagagga acatagacga   3840

ctgctgagaa aggagggagg cagcagtggt cccagcacct gaggcatcct gctgtcatgg   3900

gaaggtctcc gcccaaatgt cagatgcatc agcctgtcac ccgctggtcc agagctttca   3960

gctgtactgg tagggggtgg gtggtggagt gctgaatgac cttcacaggt gggcctttcc   4020

agctctaggg tcttacgggt gtcggtccac agaaccacgg tttttaggtt gtgtgtccgg   4080

ggctatggga acctgtcccc catgatggat cttggtagag acacttccct ctgtcatcgt   4140

gcccaggagg atgctgcagg tgactacctg cagccctgtt ctcattcatt tggatgccct   4200

ccagaaatct ggggagccat acacctttag agcctttttt gctccttatc aagttggcaa   4260

ggcttggcca attcctgttc aaggctgcat taaaggcatg ttcaccatcc tggctaatac   4320

ggtgaaaccc cttctctact aaaaatacaa aaaaattagc cgggcttggt ggcgggtgcc   4380

tgtagtccca gctactccgg aggctgaggc aggggaatgg tgtgaaccca ggaggcggag   4440

cttgcagtga gccgagatca caccactgca ctccagcctg ggctcaaaaa agaaaaaaaa   4500

aaaaaaaaaa aggcccgttc attctcaaat gcttttggcg tctccagggt gcctcaggaa   4560

aacatgaagt gggcattgta gaacttgggg ctactgtgta actttggaag aaaaagttaa   4620

gggtactttt aagtggatac tgttttgatg aaattgccaa cttcagggag cccagcttgg   4680

agaaggagga cgtgagtatt ccttacaagg ctccgaaaca attctttctt cacttagttt   4740

tctttctgtg ctctgcatct tatattccag cagggtcttc caatgcatgg tttaataact   4800

actagaactg gccaggtgca gtggctcacg cctgtaatcc cagaactttg ggaggctaag   4860

acaggcagat cacttgaggc caggagttcg agaccagcct ggacaacatg gtgataccca   4920

gtttctacta aaaatacaaa aattagtcgg gcatggtgat gtgcacctgt agtcccagct   4980

gctcgggagg ctgaggcagg agaatcgctt gaacccggga gacagaggtt gcaacgagcc   5040

aagatcgagc cactgcgctc cggcctgggt gacaggagac tccatctcaa aaaataaaat   5100

taaaaaaaaa ctactacaat aaattatcac cttggactgt ataaaacaac ttttaaacta   5160

gtctttttaa aaagtacact taaataaaaa tctaaacata agagaatgta aagtgaaaag   5220

tgaaagtatg tcttctgtta cgcagaggta actactatta ggaatccttc ctgaaaatgt   5280

ccatgcatct actcaggtca tcacacccat ggaatcattt tacatactat tttatgagtg   5340

ttacttaata tactgatcca cagtgcgttt tcacggtcac gccatcagtt gtaggagtgt   5400

gccaagaaca gatgggcctt gcctttgtac cagaggagtc catttacagt tgcaggtaat   5460

agaaaaccca attcagactg gcctaaacaa tgaggggagg ttttggctct tgaaactgga   5520

aagtcccaag gtggggtgag tttcaggttt gggttgatcc aagtggctca gtgacgtcaa   5580

caggatcttg tttccatttc tctgccttcc acagcctccc cttcatctat ggtggaggga   5640

aggagtctac cacagacaaa ccccgagcct ccccctgatg ggtggtgtgg tggtgaagcc   5700

agcaagggaa gggatccccg gacacacccc tcctcatgct ttatcccact gaaaccatgc   5760

ggctgt                                                              5766


<210>  7156
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  7156

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Asn Gln Cys Cys 
        35                  40                  45


Gly Ala Tyr Gly Pro Glu Asp Trp Asp Leu Asn Val Tyr Phe Asn Cys 
    50                  55                  60


Ser Gly Ala Ser Tyr Ser Arg Glu Lys Cys Gly Val Pro Phe Ser Cys 
65                  70                  75                  80


Cys Val Pro Asp Pro Ala Gln Lys Val Val Asn Thr Gln Cys Gly Tyr 
                85                  90                  95


Asp Val Arg Ile Gln Leu Lys Ser Lys Trp Asp Glu Ser Ile Phe Thr 
            100                 105                 110


Lys Gly Cys Ile Gln Ala Leu Glu Ser Trp Leu Pro Arg Asn Ile Tyr 
        115                 120                 125


Ile Val Ala Gly Val Phe Ile Ala Ile Ser Leu Leu Gln Ile Phe Gly 
    130                 135                 140


Ile Phe Leu Ala Arg Thr Leu Ile Ser Asp Ile Glu Ala Val Lys Ala 
145                 150                 155                 160


Gly His His Phe 



<210>  7157
<211>  2488
<212>  DNA
<213>  Homo sapiens

<400>  7157
gccgggccgc gccgccgctg ccgccgccgc gcgcggattc tgcttctcag aagatgcact     60

attatagata ctctaacgcc aaggtcagct gctggtacaa gtacctcctt ttcagctaca    120

acatcatctt ctggggtgtg ctgtccgacc tcaccaaagt gacccggatg catggaatcg    180

accctgtggt gctggtcctg atggtgggcg tggtgatgtt caccctgggg ttcgccggct    240

gcgtgggggc tctgcgggag aatatctgct tgctcaactt tttctgtggc accatcgtgc    300

tcatcttctt cctggagctg gctgtggccg tgctggcctt cctgttccag gactgggtga    360

gggaccggtt ccgggagttc ttcgagagca acatcaagtc ctaccgggac gatatcgatc    420

tgcaaaacct catcgactcc cttcagaaag ctaaccagtg ctgtggcgca tatggccctg    480

aagactggga cctcaacgtc tacttcaatt gcagcggtgc cagctacagc cgagagaagt    540

gcggggtccc cttctcctgc tgcgtgccag atcctgcgca aaaagttgtg aacacacagt    600

gtggatatga tgtcaggatt cagctgaaga gcaagtggga tgagtccatc ttcacgaaag    660

gctgcatcca ggcgctggaa agctggctcc cgcggaacat ttacattgtg gctggcgtct    720

tcatcgccat ctcgctgttg cagatatttg gcatcttcct ggcaaggacg ctgatctcag    780

acatcgaggc agtgaaggcc ggccatcact tctgaggagc agagttgagg gagccgagct    840

gagccacgct gggaggccag agcctttctc tgccatcagc cctacgtcca gagggagagg    900

agccgacacc cccagagcca gtgccccatc ttaagcatca gcgtgacgtg acctctctgt    960

ttctgcttgc tggtgctgaa gaccaagggt cccccttgtt acctgcccaa acttgtgact   1020

gcatccctct ggagtctacc cagagacaga gaatgtgtct ttatgtggga gtggtgactc   1080

tgaaagacag agagggctcc tgtggctgcc aggagggctt gactcagacc ccctgcagct   1140

caagcatgtc tgcaggacac cctggtcccc tctccactgg catccagaca tctgctttgg   1200

gtcatccaca tctgtgggtg ggccgtgggt agagggaccc acaggcgtgg acagggcatc   1260

tctctccatc aagcaaagca gcatgggggc ctgcccgtaa cgggaggcgg acgtggcccc   1320

gctgggcctc tgagtgccag cgcagtctgc tgggacatgc acatatcagg ggttgtttgc   1380

aggatcctca gccatgttca agtgaagtaa gcctgagcca gtgcgtggac tggtgccacg   1440

ggagtgcctt gtccactgtc cccctgtgtc caccagctat tctcctggcg ccggaactgc   1500

ctctggtctt gatagcatta agccctgatg gcgccggtgg cgcggtgggc atggttcttc   1560

actgagagcc ggctctcctt ttcttaaagt gtgtaaatag tttatttata ggggtaagaa   1620

tgttctcaca ccatttcact tcctcttcct ctcctccagc attctcctct gagcagcctt   1680

agatagtgtc catggctgga gccgaccctt tgagtcccct tgagtgtctt aagaaccagc   1740

ccacaacagc ctctctttct cctccacata ctgcagcctc cctccatgca tcccacatac   1800

aagcactccc ccactcccca gcgtggcctc actgtcttct ggtcttggtg ctactgaaat   1860

tgtcacccag aatttgaatc ctgaccctcc ccactgcaag cccagggagc cccagcccaa   1920

gatggccagc ctgaaactgt tggccagggc tcctcttgtg gccatgtacc cagggctggc   1980

tggcctgcca tttgcctctc cccggagaca gccgttcttc tgcaaccaca ccccgtgcct   2040

agccacaacc ccaggctgca gctgctcaga agctccaggc attttgtttc tggtgaccgc   2100

ccctaatggg atatcggtga tcactggtcc acccttcctg tcagggcttt tctggggctg   2160

ctcttggaaa tgaagtctta agtactgaat aactcccctg gggatagctg gggcatttgt   2220

ctagctgggc tactttctaa cactttgcca tagctcagac cacttctcat cgttcaggga   2280

tggactgcaa ccttaattta cttgccggag tgtacattct agtgtggtgt atactggtgg   2340

ctgttgatga tgattttttt ttttttacac aattctctgt agactaggag aagaatgctt   2400

gtgtttttcg gaagtgtgat gcttctcttt gactgccaaa ctcttttatg gaatatatct   2460

ttatattaat gctgttttgg tcattttt                                      2488


<210>  7158
<211>  253
<212>  PRT
<213>  Homo sapiens

<400>  7158

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Gly Val Leu Ser Asp 
            20                  25                  30


Leu Thr Lys Val Thr Arg Met His Gly Ile Asp Pro Val Val Leu Val 
        35                  40                  45


Leu Met Val Gly Val Val Met Phe Thr Leu Gly Phe Ala Gly Cys Val 
    50                  55                  60


Gly Ala Leu Arg Glu Asn Ile Cys Leu Leu Asn Phe Phe Cys Gly Thr 
65                  70                  75                  80


Ile Val Leu Ile Phe Phe Leu Glu Leu Ala Val Ala Val Leu Ala Phe 
                85                  90                  95


Leu Phe Gln Asp Trp Val Arg Asp Arg Phe Arg Glu Phe Phe Glu Ser 
            100                 105                 110


Asn Ile Lys Ser Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile Asp 
        115                 120                 125


Ser Leu Gln Lys Ala Asn Gln Cys Cys Gly Ala Tyr Gly Pro Glu Asp 
    130                 135                 140


Trp Asp Leu Asn Val Tyr Phe Asn Cys Ser Gly Ala Ser Tyr Ser Arg 
145                 150                 155                 160


Glu Lys Cys Gly Val Pro Phe Ser Cys Cys Val Pro Asp Pro Ala Gln 
                165                 170                 175


Lys Val Val Asn Thr Gln Cys Gly Tyr Asp Val Arg Ile Gln Leu Lys 
            180                 185                 190


Ser Lys Trp Asp Glu Ser Ile Phe Thr Lys Gly Cys Ile Gln Ala Leu 
        195                 200                 205


Glu Ser Trp Leu Pro Arg Asn Ile Tyr Ile Val Ala Gly Val Phe Ile 
    210                 215                 220


Ala Ile Ser Leu Leu Gln Ile Phe Gly Ile Phe Leu Ala Arg Thr Leu 
225                 230                 235                 240


Ile Ser Asp Ile Glu Ala Val Lys Ala Gly His His Phe 
                245                 250


<210>  7159
<211>  673
<212>  DNA
<213>  Homo sapiens

<400>  7159
gggcaggctg gggttgaaac tcttcacccc ttgcggtctg tactgcctcc caactgagca     60

gccagggaga aggcctagag cctgtgcctt tcagctagat agctggagga actggctcct    120

ccctccttag gctgtgctgg cctgagctgg gagcctgaga gctggggcag ttgtctctaa    180

agtggcttct gggattctgg taagaggact tggggtggag tcgaaagcag ggagccctgt    240

gagttgagac gaactcttgc aatgttgcct tggctggtct cgaactcatc ttctgggttc    300

aagctgtccg tctgcctcgg actcccaaag tgctaggatt acagcgttac atccttacta    360

ttcaaagtgc catccacaga cctgctgatg ggcagcatga gcatcacctg ggagcttgct    420

gcgctgtaga atcttgaggg gtctccatcc agatcagctg aatcagagtt tgcattgtta    480

acaagattct gcttctcaga agatgcacta ttatagatac tctaacgcca aggtcagctg    540

ctggtacaag tacctccttt tcagctacaa catcatcttc tggttggctg gagttgtctt    600

ccttggagtc gggctgtggg catggagcga aaagggtgtg ctgtccgacc tcaccaaagt    660

gacccggatg cat                                                       673


<210>  7160
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  7160

Met His Tyr Tyr Arg Tyr Ser Asn Ala Lys Val Ser Cys Trp Tyr Lys 
1               5                   10                  15


Tyr Leu Leu Phe Ser Tyr Asn Ile Ile Phe Trp Leu Ala Gly Val Val 
            20                  25                  30


Phe Leu Gly Val Gly Leu Trp Ala Trp Ser Glu Lys Gly Val Leu Ser 
        35                  40                  45


Asp Leu Thr Lys Val Thr Arg Met 
    50                  55


<210>  7161
<211>  1230
<212>  DNA
<213>  Homo sapiens

<400>  7161
gcgttacatc cttactattc aaagtgccat ccacagacct gctgatgggc agcatgagca     60

tcactgggcc tctgagtgcc agcgcagtct gctgggacat gcacatatca ggggttgttt    120

gcaggatcct cagccatgtt caagtgaagt aagcctgagc cagtgcgtgg actggtgcca    180

cgggagtgcc ttgtccactg tccccctgtg tccaccagct attctcctgg cgccggaact    240

gcctctggtc ttgatagcat taagccctga tggcgccggt ggcgcggtgg gcatggttct    300

tcactgagag ccggctctcc ttttcttaaa gtgtgtaaat agtttattta taggggtaag    360

aatgttctca caccatttca cttcctcttc ctctcctcca gcattctcct ctgagcagcc    420

ttagatagtg tccatggctg gagccgaccc tttgagtccc cttgagtgtc ttaagaacca    480

gcccacaaca gcctctcttt ctcctccaca tactgcagcc tccctccatg catcccacat    540

acaagcactc ccccactccc cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa    600

attgtcaccc agaatttgaa tcctgaccct ccccactgca agcccaggga gccccagccc    660

aagatggcca gcctgaaact gttggccagg gctcctcttg tggccatgta cccagggctg    720

gctggcctgc catttgcctc tccccggaga cagccgttct tctgcaacca caccccgtgc    780

ctagccacaa ccccaggctg cagctgctca gaagctccag gcattttgtt tctggtgacc    840

gcccctaatg ggatatcggt gatcactggt ccacccttcc tgtcagggct tttctggggc    900

tgctcttgga aatgaagtct taagtactga ataactcccc tggggatagc tggggcattt    960

gtctagctgg gctactttct aacactttgc catagctcag accacttctc atcgttcagg   1020

gatggactgc aaccttaatt tacttgccgg agtgtacatt ctagtgtggt gtatactggt   1080

ggctgttgat gatgattttt ttttttttac acaattctct gtagactagg agaagaatgc   1140

ttgtgttttt cggaagtgtg atgcttctct ttgactgcca aactctttta tggaatatat   1200

ctttatatta atgctgtttt ggtcattttt                                    1230


<210>  7162
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  7162

Met Gly Ser Met Ser Ile Thr Gly Pro Leu Ser Ala Ser Ala Val Cys 
1               5                   10                  15


Trp Asp Met His Ile Ser Gly Val Val Cys Arg Ile Leu Ser His Val 
            20                  25                  30


Gln Val Lys 
        35


<210>  7163
<211>  2651
<212>  DNA
<213>  Homo sapiens

<400>  7163
gcgttacatc cttactattc aaagtgccat ccacagacct gctgatgggc agcatgagca     60

tcactgggcc tctgagtgcc agcgcagtct gctgggacat gcacatatca ggggttgttt    120

gcaggatcct cagccatgtt caagtgaagt aagcctgagc cagtgcgtgg actggtgcca    180

cgggagtgcc ttgtccactg tccccctgtg tccaccagct attctcctgg cgccggaact    240

gcctctggtc ttgatagcat taagccctga tggcgccggt ggcgcggtgg gcatggttct    300

tcactgagag ccggctctcc ttttcttaaa gtgtgtaaat agtttattta taggggtaag    360

aatgttctca caccatttca cttcctcttc ctctcctcca gcattctcct ctgagcagcc    420

ttagatagtg tccatggctg gagccgaccc tttgagtccc cttgagtgtc ttaagaacca    480

gcccacaaca gcctctcttt ctcctccaca tactgcagcc tccctccatg catcccacat    540

acaagcactc ccccactccc cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa    600

attgtcaccc agaatttgaa tcctgaccct ccccactgca agcccaggga gccccagccc    660

aagatggcca gcctgaaact gttggccagg gctcctcttg tggccatgta cccagggctg    720

gctggcctgc catttgcctc tccccggaga cagccgttct tctgcaacca caccccgtgc    780

ctagccacaa ccccaggctg cagctgctca gaagctccag gcattttgtt tctggtgacc    840

gcccctaatg ggatatcggt gatcactggt ccacccttcc tgtcagggct tttctggggc    900

tgctcttgga aatgaagtct taagtactga ataactcccc tggggatagc tggggcattt    960

gtctagctgg gctactttct aacactttgc catagctcag accacttctc atcgttcagg   1020

gatggactgc aaccttaatt tacttgccgg agtgtacatt ctagtgtggt gtatactggt   1080

ggctgttgat gatgattttt ttttttttac acaattctct gtagactagg agaagaatgc   1140

ttgtgttttt cggaagtgtg atgcttctct ttgactgcca aactctttta tggaatatat   1200

ctttatatta atgctgtttt ggtcattttt gtttggggtc actattgaga tattgctaag   1260

catctcagtg gtaaacgcgg ctgccagagg aaccaaggga tagggtatgt agaccttaca   1320

gaaggatgga tggtaaaggc agtccatcat cagcacaatc tgacttacat ttcattgagt   1380

aatttttttt ttttttaaga ttctgtatgg cagcactttc agttgccctt gtgtgccggc   1440

cacagccgca caagttggct tgtggtttat cccccgctat aagtgagagc tggagaaact   1500

tcaactccat aggtctagag gaaacattgt tttaggttat ttctgtccac ccctgtgcga   1560

tactatttat tgatccaagc agaagagctt ggggacactg agtcgaagtg gggacatggg   1620

attgaagcct gggcactgct gctgcatgag ctgtgtgtcc tgggtgtgcc ggcctttctg   1680

tgaagggggt tggtggcagt gcccacctca ctagatgcct ctgacccagc ctcccctggg   1740

ggagtgggtg gccacagacc ctccctgcca gagctcctgg aaggctcctg caggcctgac   1800

ccatctattc ctgtagacct ggtttaggat gaagtctcgg tgcgattttt gcagagttgg   1860

gtttatcttt caactataga cccttctggc tgttctcagc catatcatgt gactctgaat   1920

agttggatga ggaatggaaa gaaagcaagg atgagagccg gtcacgtggc agtctccgcc   1980

cagcatcggc tgtccgcaca gaggcacagg gcaggcctcc tgtgcactcc ccacctagca   2040

ctggcctgtc ctgaatcccc gccttccctg gttggaggcc agctgtggca tttgcaccct   2100

cttctcacct caccatgcac atgctaactt taaagccttg gggtctttcc tgtaccccct   2160

cctcaaccct ggtccacccc ctctcaggat cttgtcaacg ttatttttcc tgtcccgtct   2220

tcctatcgct ggccttcctt tcccatccta aaaacttgcc gaggccctat ggctccctcc   2280

ctttctttcc caggcagctt cttatctggg ctgtctgtac cccttccttt gcaccaccca   2340

ccatgcccca cgtagctgaa agctgcttat cccaattgtc aactctggcc ttcttcagcc   2400

tctgtagcac cagacactgc acctcctgaa tgtcctctgc ttctctgctt cagaggccca   2460

ggctcgccag ttctctgacc tctcccatat gtctgcttag gactctgctg cagctgtcct   2520

caccagcctc cggggaatcc cactacccac agggcagggc tgtgggctgg gctgaaaaac   2580

catctgcatg gtccacaaga agcctggcac tgggtttccc catgaataac aatgaaaatt   2640

aatggatgca c                                                        2651


<210>  7164
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  7164

Met Gly Ser Met Ser Ile Thr Gly Pro Leu Ser Ala Ser Ala Val Cys 
1               5                   10                  15


Trp Asp Met His Ile Ser Gly Val Val Cys Arg Ile Leu Ser His Val 
            20                  25                  30


Gln Val Lys 
        35


<210>  7165
<211>  4766
<212>  DNA
<213>  Homo sapiens

<400>  7165
gcgttacatc cttactattc aaagtgccat ccacagacct gctgatgggc agcatgagca     60

tcactgggcc tctgagtgcc agcgcagtct gctgggacat gcacatatca ggggttgttt    120

gcaggatcct cagccatgtt caagtgaagt aagcctgagc cagtgcgtgg actggtgcca    180

cgggagtgcc ttgtccactg tccccctgtg tccaccagct attctcctgg cgccggaact    240

gcctctggtc ttgatagcat taagccctga tggcgccggt ggcgcggtgg gcatggttct    300

tcactgagag ccggctctcc ttttcttaaa gtgtgtaaat agtttattta taggggtaag    360

aatgttctca caccatttca cttcctcttc ctctcctcca gcattctcct ctgagcagcc    420

ttagatagtg tccatggctg gagccgaccc tttgagtccc cttgagtgtc ttaagaacca    480

gcccacaaca gcctctcttt ctcctccaca tactgcagcc tccctccatg catcccacat    540

acaagcactc ccccactccc cagcgtggcc tcactgtctt ctggtcttgg tgctactgaa    600

attgtcaccc agaatttgaa tcctgaccct ccccactgca agcccaggga gccccagccc    660

aagatggcca gcctgaaact gttggccagg gctcctcttg tggccatgta cccagggctg    720

gctggcctgc catttgcctc tccccggaga cagccgttct tctgcaacca caccccgtgc    780

ctagccacaa ccccaggctg cagctgctca gaagctccag gcattttgtt tctggtgacc    840

gcccctaatg ggatatcggt gatcactggt ccacccttcc tgtcagggct tttctggggc    900

tgctcttgga aatgaagtct taagtactga ataactcccc tggggatagc tggggcattt    960

gtctagctgg gctactttct aacactttgc catagctcag accacttctc atcgttcagg   1020

gatggactgc aaccttaatt tacttgccgg agtgtacatt ctagtgtggt gtatactggt   1080

ggctgttgat gatgattttt ttttttttac acaattctct gtagactagg agaagaatgc   1140

ttgtgttttt cggaagtgtg atgcttctct ttgactgcca aactctttta tggaatatat   1200

ctttatatta atgctgtttt ggtcattttt gtttggggtc actattgaga tattgctaag   1260

catctcagtg gtaaacgcgg ctgccagagg aaccaaggga tagggtatgt agaccttaca   1320

gaaggatgga tggtaaaggc agtccatcat cagcacaatc tgacttacat ttcattgagt   1380

aatttttttt ttttttaaga ttctgtatgg cagcactttc agttgccctt gtgtgccggc   1440

cacagccgca caagttggct tgtggtttat cccccgctat aagtgagagc tggagaaact   1500

tcaactccat aggtctagag gaaacattgt tttaggttat ttctgtccac ccctgtgcga   1560

tactatttat tgatccaagc agaagagctt ggggacactg agtcgaagtg gggacatggg   1620

attgaagcct gggcactgct gctgcatgag ctgtgtgtcc tgggtgtgcc ggcctttctg   1680

tgaagggggt tggtggcagt gcccacctca ctagatgcct ctgacccagc ctcccctggg   1740

ggagtgggtg gccacagacc ctccctgcca gagctcctgg aaggctcctg caggcctgac   1800

ccatctattc ctgtagacct ggtttaggat gaagtctcgg tgcgattttt gcagagttgg   1860

gtttatcttt caactataga cccttctggc tgttctcagc catatcatgt gactctgaat   1920

agttggatga ggaatggaaa gaaagcaagg atgagagccg gtcacgtggc agtctccgcc   1980

cagcatcggc tgtccgcaca gaggcacagg gcaggcctcc tgtgcactcc ccacctagca   2040

ctggcctgtc ctgaatcccc gccttccctg gttggaggcc agctgtggca tttgcaccct   2100

cttctcacct caccatgcac atgctaactt taaagccttg gggtctttcc tgtaccccct   2160

cctcaaccct ggtccacccc ctctcaggat cttgtcaacg ttatttttcc tgtcccgtct   2220

tcctatcgct ggccttcctt tcccatccta aaaacttgcc gaggccctat ggctccctcc   2280

ctttctttcc caggcagctt cttatctggg ctgtctgtac cccttccttt gcaccaccca   2340

ccatgcccca cgtagctgaa agctgcttat cccaattgtc aactctggcc ttcttcagcc   2400

tctgtagcac cagacactgc acctcctgaa tgtcctctgc ttctctgctt cagaggccca   2460

ggctcgccag ttctctgacc tctcccatat gtctgcttag gactctgctg cagctgtcct   2520

caccagcctc cggggaatcc cactacccac agggcagggc tgtgggctgg gctgaaaaac   2580

catctgcatg gtccacaaga agcctggcac tgggtttccc catgaataac aatgaaaatt   2640

aatggatgca caaccttcct ggaacgtgga atttctctgg gagattccat gcagaggcca   2700

ctggggaggt ggcaggcatg catgtgactg taggtggctg cagtgttgga aggctcccag   2760

cagagcagag agggtgtcag tctcatcagg gaacccacct gatggcttct cagccagcag   2820

tctcagagga acatagacga ctgctgagaa aggagggagg cagcagtggt cccagcacct   2880

gaggcatcct gctgtcatgg gaaggtctcc gcccaaatgt cagatgcatc agcctgtcac   2940

ccgctggtcc agagctttca gctgtactgg tagggggtgg gtggtggagt gctgaatgac   3000

cttcacaggt gggcctttcc agctctaggg tcttacgggt gtcggtccac agaaccacgg   3060

tttttaggtt gtgtgtccgg ggctatggga acctgtcccc catgatggat cttggtagag   3120

acacttccct ctgtcatcgt gcccaggagg atgctgcagg tgactacctg cagccctgtt   3180

ctcattcatt tggatgccct ccagaaatct ggggagccat acacctttag agcctttttt   3240

gctccttatc aagttggcaa ggcttggcca attcctgttc aaggctgcat taaaggcatg   3300

ttcaccatcc tggctaatac ggtgaaaccc cttctctact aaaaatacaa aaaaattagc   3360

cgggcttggt ggcgggtgcc tgtagtccca gctactccgg aggctgaggc aggggaatgg   3420

tgtgaaccca ggaggcggag cttgcagtga gccgagatca caccactgca ctccagcctg   3480

ggctcaaaaa agaaaaaaaa aaaaaaaaaa aggcccgttc attctcaaat gcttttggcg   3540

tctccagggt gcctcaggaa aacatgaagt gggcattgta gaacttgggg ctactgtgta   3600

actttggaag aaaaagttaa gggtactttt aagtggatac tgttttgatg aaattgccaa   3660

cttcagggag cccagcttgg agaaggagga cgtgagtatt ccttacaagg ctccgaaaca   3720

attctttctt cacttagttt tctttctgtg ctctgcatct tatattccag cagggtcttc   3780

caatgcatgg tttaataact actagaactg gccaggtgca gtggctcacg cctgtaatcc   3840

cagaactttg ggaggctaag acaggcagat cacttgaggc caggagttcg agaccagcct   3900

ggacaacatg gtgataccca gtttctacta aaaatacaaa aattagtcgg gcatggtgat   3960

gtgcacctgt agtcccagct gctcgggagg ctgaggcagg agaatcgctt gaacccggga   4020

gacagaggtt gcaacgagcc aagatcgagc cactgcgctc cggcctgggt gacaggagac   4080

tccatctcaa aaaataaaat taaaaaaaaa ctactacaat aaattatcac cttggactgt   4140

ataaaacaac ttttaaacta gtctttttaa aaagtacact taaataaaaa tctaaacata   4200

agagaatgta aagtgaaaag tgaaagtatg tcttctgtta cgcagaggta actactatta   4260

ggaatccttc ctgaaaatgt ccatgcatct actcaggtca tcacacccat ggaatcattt   4320

tacatactat tttatgagtg ttacttaata tactgatcca cagtgcgttt tcacggtcac   4380

gccatcagtt gtaggagtgt gccaagaaca gatgggcctt gcctttgtac cagaggagtc   4440

catttacagt tgcaggtaat agaaaaccca attcagactg gcctaaacaa tgaggggagg   4500

ttttggctct tgaaactgga aagtcccaag gtggggtgag tttcaggttt gggttgatcc   4560

aagtggctca gtgacgtcaa caggatcttg tttccatttc tctgccttcc acagcctccc   4620

cttcatctat ggtggaggga aggagtctac cacagacaaa ccccgagcct ccccctgatg   4680

ggtggtgtgg tggtgaagcc agcaagggaa gggatccccg gacacacccc tcctcatgct   4740

ttatcccact gaaaccatgc ggctgt                                        4766


<210>  7166
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  7166

Met Gly Ser Met Ser Ile Thr Gly Pro Leu Ser Ala Ser Ala Val Cys 
1               5                   10                  15


Trp Asp Met His Ile Ser Gly Val Val Cys Arg Ile Leu Ser His Val 
            20                  25                  30


Gln Val Lys 
        35


<210>  7167
<211>  463
<212>  DNA
<213>  Homo sapiens

<400>  7167
aaatcctcct ggggccttcg gagatccttc catctggacc agtgcacaga attcccttta     60

catcttttgg gatacaccct aaagaagatc cagtctttgt tcaccttcac gagtttcttc    120

aatgtgaaag ctacaggagg ctttgttcaa agaaactctg acccagaaac ccaacatgga    180

agcaggcaga gcaggacact tttatcttca ggtggctggg ggaaaggaag gcttcacaag    240

gtgcacacta aaaaccatgg gcctactgtg actgacgcca tgctccacag gacagcagaa    300

cggctcagga gctgcctcca gaatcatatg gcaactagtt caacagaact gtgatagact    360

tggaaatgca tgttttgaag agctgtcatt cacagcagct tgaaaaagcc cccactggcc    420

aaatctggaa caatctgagc ggcaaaataa acaataataa caa                      463


<210>  7168
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  7168

Met Glu Ala Gly Arg Ala Gly His Phe Tyr Leu Gln Val Ala Gly Gly 
1               5                   10                  15


Lys Glu Gly Phe Thr Arg Cys Thr Leu Lys Thr Met Gly Leu Leu 
            20                  25                  30


<210>  7169
<211>  257
<212>  DNA
<213>  Homo sapiens

<400>  7169
ataaaaattt gtaagcatgt gcttaaaggc caaagtggaa tgttaagagc atgaaaatgg     60

ctgcatgggg tggtggtgga cttacaagtg attttccaaa aaggtttcca gcatcacact    120

taccattacc acctttgtat tataaatgaa aatggggccg ctgctggttg gaggtgcccc    180

tgctgggaag gagaatgctt gctacaatat ataaggctgg cagtcatcat aaacagggct    240

ccttggcttc agtgttg                                                   257


<210>  7170
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7170

Met Lys Met Ala Ala Trp Gly Gly Gly Gly Leu Thr Ser Asp Phe Pro 
1               5                   10                  15


Lys Arg Phe Pro Ala Ser His Leu Pro Leu Pro Pro Leu Tyr Tyr Lys 
            20                  25                  30


<210>  7171
<211>  601
<212>  DNA
<213>  Homo sapiens

<400>  7171
agttggctgg agttgtcttc cttggagtcg ggctgtgggc atggagcgaa aagggtgtgc     60

tgtccgacct caccaaagtg acccagggct ggctggcctg ccatttgcct ctccccggag    120

acagccgttc ttctgcaacc acaccccgtg cctagccaca accccaggct gcagctgctc    180

agaagctcca ggcattttgt ttctggtgac cgcccctaat gggatatcgg tgatcactgg    240

tccacccttc ctgtcagggc ttttctgggg ctgctcttgg aaatgaagtc ttaagtactg    300

aataactccc ctggggatag ctggggcatt tgtctagctg ggctactttc taacactttg    360

ccatagctca gaccacttct catcgttcag ggatggactg caaccttaat ttacttgccg    420

gagtgtacat tctagtgtgg tgtatactgg tggctgttga tgatgatttt ttttttttta    480

cacaattctc tgtagactag gagaagaatg cttgtgtttt tcggaagtgt gatgcttctc    540

tttgactgcc aaactctttt atggaatata tctttatatt aatgctgttt tggtcatttt    600

t                                                                    601


<210>  7172
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  7172

Met Glu Arg Lys Gly Cys Ala Val Arg Pro His Gln Ser Asp Pro Gly 
1               5                   10                  15


Leu Ala Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys 
            20                  25                  30


Asn His Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu 
        35                  40                  45


Ala Pro Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val 
    50                  55                  60


Ile Thr Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp 
65                  70                  75                  80


Lys 



<210>  7173
<211>  2022
<212>  DNA
<213>  Homo sapiens

<400>  7173
agttggctgg agttgtcttc cttggagtcg ggctgtgggc atggagcgaa aagggtgtgc     60

tgtccgacct caccaaagtg acccagggct ggctggcctg ccatttgcct ctccccggag    120

acagccgttc ttctgcaacc acaccccgtg cctagccaca accccaggct gcagctgctc    180

agaagctcca ggcattttgt ttctggtgac cgcccctaat gggatatcgg tgatcactgg    240

tccacccttc ctgtcagggc ttttctgggg ctgctcttgg aaatgaagtc ttaagtactg    300

aataactccc ctggggatag ctggggcatt tgtctagctg ggctactttc taacactttg    360

ccatagctca gaccacttct catcgttcag ggatggactg caaccttaat ttacttgccg    420

gagtgtacat tctagtgtgg tgtatactgg tggctgttga tgatgatttt ttttttttta    480

cacaattctc tgtagactag gagaagaatg cttgtgtttt tcggaagtgt gatgcttctc    540

tttgactgcc aaactctttt atggaatata tctttatatt aatgctgttt tggtcatttt    600

tgtttggggt cactattgag atattgctaa gcatctcagt ggtaaacgcg gctgccagag    660

gaaccaaggg atagggtatg tagaccttac agaaggatgg atggtaaagg cagtccatca    720

tcagcacaat ctgacttaca tttcattgag taattttttt tttttttaag attctgtatg    780

gcagcacttt cagttgccct tgtgtgccgg ccacagccgc acaagttggc ttgtggttta    840

tcccccgcta taagtgagag ctggagaaac ttcaactcca taggtctaga ggaaacattg    900

ttttaggtta tttctgtcca cccctgtgcg atactattta ttgatccaag cagaagagct    960

tggggacact gagtcgaagt ggggacatgg gattgaagcc tgggcactgc tgctgcatga   1020

gctgtgtgtc ctgggtgtgc cggcctttct gtgaaggggg ttggtggcag tgcccacctc   1080

actagatgcc tctgacccag cctcccctgg gggagtgggt ggccacagac cctccctgcc   1140

agagctcctg gaaggctcct gcaggcctga cccatctatt cctgtagacc tggtttagga   1200

tgaagtctcg gtgcgatttt tgcagagttg ggtttatctt tcaactatag acccttctgg   1260

ctgttctcag ccatatcatg tgactctgaa tagttggatg aggaatggaa agaaagcaag   1320

gatgagagcc ggtcacgtgg cagtctccgc ccagcatcgg ctgtccgcac agaggcacag   1380

ggcaggcctc ctgtgcactc cccacctagc actggcctgt cctgaatccc cgccttccct   1440

ggttggaggc cagctgtggc atttgcaccc tcttctcacc tcaccatgca catgctaact   1500

ttaaagcctt ggggtctttc ctgtaccccc tcctcaaccc tggtccaccc cctctcagga   1560

tcttgtcaac gttatttttc ctgtcccgtc ttcctatcgc tggccttcct ttcccatcct   1620

aaaaacttgc cgaggcccta tggctccctc cctttctttc ccaggcagct tcttatctgg   1680

gctgtctgta ccccttcctt tgcaccaccc accatgcccc acgtagctga aagctgctta   1740

tcccaattgt caactctggc cttcttcagc ctctgtagca ccagacactg cacctcctga   1800

atgtcctctg cttctctgct tcagaggccc aggctcgcca gttctctgac ctctcccata   1860

tgtctgctta ggactctgct gcagctgtcc tcaccagcct ccggggaatc ccactaccca   1920

cagggcaggg ctgtgggctg ggctgaaaaa ccatctgcat ggtccacaag aagcctggca   1980

ctgggtttcc ccatgaataa caatgaaaat taatggatgc ac                      2022


<210>  7174
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  7174

Met Glu Arg Lys Gly Cys Ala Val Arg Pro His Gln Ser Asp Pro Gly 
1               5                   10                  15


Leu Ala Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys 
            20                  25                  30


Asn His Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu 
        35                  40                  45


Ala Pro Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val 
    50                  55                  60


Ile Thr Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp 
65                  70                  75                  80


Lys 



<210>  7175
<211>  4137
<212>  DNA
<213>  Homo sapiens

<400>  7175
agttggctgg agttgtcttc cttggagtcg ggctgtgggc atggagcgaa aagggtgtgc     60

tgtccgacct caccaaagtg acccagggct ggctggcctg ccatttgcct ctccccggag    120

acagccgttc ttctgcaacc acaccccgtg cctagccaca accccaggct gcagctgctc    180

agaagctcca ggcattttgt ttctggtgac cgcccctaat gggatatcgg tgatcactgg    240

tccacccttc ctgtcagggc ttttctgggg ctgctcttgg aaatgaagtc ttaagtactg    300

aataactccc ctggggatag ctggggcatt tgtctagctg ggctactttc taacactttg    360

ccatagctca gaccacttct catcgttcag ggatggactg caaccttaat ttacttgccg    420

gagtgtacat tctagtgtgg tgtatactgg tggctgttga tgatgatttt ttttttttta    480

cacaattctc tgtagactag gagaagaatg cttgtgtttt tcggaagtgt gatgcttctc    540

tttgactgcc aaactctttt atggaatata tctttatatt aatgctgttt tggtcatttt    600

tgtttggggt cactattgag atattgctaa gcatctcagt ggtaaacgcg gctgccagag    660

gaaccaaggg atagggtatg tagaccttac agaaggatgg atggtaaagg cagtccatca    720

tcagcacaat ctgacttaca tttcattgag taattttttt tttttttaag attctgtatg    780

gcagcacttt cagttgccct tgtgtgccgg ccacagccgc acaagttggc ttgtggttta    840

tcccccgcta taagtgagag ctggagaaac ttcaactcca taggtctaga ggaaacattg    900

ttttaggtta tttctgtcca cccctgtgcg atactattta ttgatccaag cagaagagct    960

tggggacact gagtcgaagt ggggacatgg gattgaagcc tgggcactgc tgctgcatga   1020

gctgtgtgtc ctgggtgtgc cggcctttct gtgaaggggg ttggtggcag tgcccacctc   1080

actagatgcc tctgacccag cctcccctgg gggagtgggt ggccacagac cctccctgcc   1140

agagctcctg gaaggctcct gcaggcctga cccatctatt cctgtagacc tggtttagga   1200

tgaagtctcg gtgcgatttt tgcagagttg ggtttatctt tcaactatag acccttctgg   1260

ctgttctcag ccatatcatg tgactctgaa tagttggatg aggaatggaa agaaagcaag   1320

gatgagagcc ggtcacgtgg cagtctccgc ccagcatcgg ctgtccgcac agaggcacag   1380

ggcaggcctc ctgtgcactc cccacctagc actggcctgt cctgaatccc cgccttccct   1440

ggttggaggc cagctgtggc atttgcaccc tcttctcacc tcaccatgca catgctaact   1500

ttaaagcctt ggggtctttc ctgtaccccc tcctcaaccc tggtccaccc cctctcagga   1560

tcttgtcaac gttatttttc ctgtcccgtc ttcctatcgc tggccttcct ttcccatcct   1620

aaaaacttgc cgaggcccta tggctccctc cctttctttc ccaggcagct tcttatctgg   1680

gctgtctgta ccccttcctt tgcaccaccc accatgcccc acgtagctga aagctgctta   1740

tcccaattgt caactctggc cttcttcagc ctctgtagca ccagacactg cacctcctga   1800

atgtcctctg cttctctgct tcagaggccc aggctcgcca gttctctgac ctctcccata   1860

tgtctgctta ggactctgct gcagctgtcc tcaccagcct ccggggaatc ccactaccca   1920

cagggcaggg ctgtgggctg ggctgaaaaa ccatctgcat ggtccacaag aagcctggca   1980

ctgggtttcc ccatgaataa caatgaaaat taatggatgc acaaccttcc tggaacgtgg   2040

aatttctctg ggagattcca tgcagaggcc actggggagg tggcaggcat gcatgtgact   2100

gtaggtggct gcagtgttgg aaggctccca gcagagcaga gagggtgtca gtctcatcag   2160

ggaacccacc tgatggcttc tcagccagca gtctcagagg aacatagacg actgctgaga   2220

aaggagggag gcagcagtgg tcccagcacc tgaggcatcc tgctgtcatg ggaaggtctc   2280

cgcccaaatg tcagatgcat cagcctgtca cccgctggtc cagagctttc agctgtactg   2340

gtagggggtg ggtggtggag tgctgaatga ccttcacagg tgggcctttc cagctctagg   2400

gtcttacggg tgtcggtcca cagaaccacg gtttttaggt tgtgtgtccg gggctatggg   2460

aacctgtccc ccatgatgga tcttggtaga gacacttccc tctgtcatcg tgcccaggag   2520

gatgctgcag gtgactacct gcagccctgt tctcattcat ttggatgccc tccagaaatc   2580

tggggagcca tacaccttta gagccttttt tgctccttat caagttggca aggcttggcc   2640

aattcctgtt caaggctgca ttaaaggcat gttcaccatc ctggctaata cggtgaaacc   2700

ccttctctac taaaaataca aaaaaattag ccgggcttgg tggcgggtgc ctgtagtccc   2760

agctactccg gaggctgagg caggggaatg gtgtgaaccc aggaggcgga gcttgcagtg   2820

agccgagatc acaccactgc actccagcct gggctcaaaa aagaaaaaaa aaaaaaaaaa   2880

aaggcccgtt cattctcaaa tgcttttggc gtctccaggg tgcctcagga aaacatgaag   2940

tgggcattgt agaacttggg gctactgtgt aactttggaa gaaaaagtta agggtacttt   3000

taagtggata ctgttttgat gaaattgcca acttcaggga gcccagcttg gagaaggagg   3060

acgtgagtat tccttacaag gctccgaaac aattctttct tcacttagtt ttctttctgt   3120

gctctgcatc ttatattcca gcagggtctt ccaatgcatg gtttaataac tactagaact   3180

ggccaggtgc agtggctcac gcctgtaatc ccagaacttt gggaggctaa gacaggcaga   3240

tcacttgagg ccaggagttc gagaccagcc tggacaacat ggtgataccc agtttctact   3300

aaaaatacaa aaattagtcg ggcatggtga tgtgcacctg tagtcccagc tgctcgggag   3360

gctgaggcag gagaatcgct tgaacccggg agacagaggt tgcaacgagc caagatcgag   3420

ccactgcgct ccggcctggg tgacaggaga ctccatctca aaaaataaaa ttaaaaaaaa   3480

actactacaa taaattatca ccttggactg tataaaacaa cttttaaact agtcttttta   3540

aaaagtacac ttaaataaaa atctaaacat aagagaatgt aaagtgaaaa gtgaaagtat   3600

gtcttctgtt acgcagaggt aactactatt aggaatcctt cctgaaaatg tccatgcatc   3660

tactcaggtc atcacaccca tggaatcatt ttacatacta ttttatgagt gttacttaat   3720

atactgatcc acagtgcgtt ttcacggtca cgccatcagt tgtaggagtg tgccaagaac   3780

agatgggcct tgcctttgta ccagaggagt ccatttacag ttgcaggtaa tagaaaaccc   3840

aattcagact ggcctaaaca atgaggggag gttttggctc ttgaaactgg aaagtcccaa   3900

ggtggggtga gtttcaggtt tgggttgatc caagtggctc agtgacgtca acaggatctt   3960

gtttccattt ctctgccttc cacagcctcc ccttcatcta tggtggaggg aaggagtcta   4020

ccacagacaa accccgagcc tccccctgat gggtggtgtg gtggtgaagc cagcaaggga   4080

agggatcccc ggacacaccc ctcctcatgc tttatcccac tgaaaccatg cggctgt      4137


<210>  7176
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  7176

Met Glu Arg Lys Gly Cys Ala Val Arg Pro His Gln Ser Asp Pro Gly 
1               5                   10                  15


Leu Ala Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys 
            20                  25                  30


Asn His Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu 
        35                  40                  45


Ala Pro Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val 
    50                  55                  60


Ile Thr Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp 
65                  70                  75                  80


Lys 



<210>  7177
<211>  519
<212>  DNA
<213>  Homo sapiens

<400>  7177
agaagacgtc tctcgttaag gggacagctg caggagtgta ggtgccttgt tctggcctcc     60

gtgtggaggc agtagtgaca aagagggagg caggcctggg gcaggggcga ggctctgtcc    120

tccaggcatt ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc    180

cttcctgtca gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac    240

tcccctgggg atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag    300

ctcagaccac ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt    360

acattctagt gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat    420

tctctgtaga ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac    480

tgccaaactc ttttatggaa tatatcttta tattaatgc                           519


<210>  7178
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  7178

Met Asp Cys Asn Leu Asn Leu Leu Ala Gly Val Tyr Ile Leu Val Trp 
1               5                   10                  15


Cys Ile Leu Val Ala Val Asp Asp Asp Phe Phe Phe Phe Thr Gln Phe 
            20                  25                  30


Ser Val Asp 
        35


<210>  7179
<211>  1956
<212>  DNA
<213>  Homo sapiens

<400>  7179
agaagacgtc tctcgttaag gggacagctg caggagtgta ggtgccttgt tctggcctcc     60

gtgtggaggc agtagtgaca aagagggagg caggcctggg gcaggggcga ggctctgtcc    120

tccaggcatt ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc    180

cttcctgtca gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac    240

tcccctgggg atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag    300

ctcagaccac ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt    360

acattctagt gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat    420

tctctgtaga ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac    480

tgccaaactc ttttatggaa tatatcttta tattaatgct gttttggtca tttttgtttg    540

gggtcactat tgagatattg ctaagcatct cagtggtaaa cgcggctgcc agaggaacca    600

agggataggg tatgtagacc ttacagaagg atggatggta aaggcagtcc atcatcagca    660

caatctgact tacatttcat tgagtaattt tttttttttt taagattctg tatggcagca    720

ctttcagttg cccttgtgtg ccggccacag ccgcacaagt tggcttgtgg tttatccccc    780

gctataagtg agagctggag aaacttcaac tccataggtc tagaggaaac attgttttag    840

gttatttctg tccacccctg tgcgatacta tttattgatc caagcagaag agcttgggga    900

cactgagtcg aagtggggac atgggattga agcctgggca ctgctgctgc atgagctgtg    960

tgtcctgggt gtgccggcct ttctgtgaag ggggttggtg gcagtgccca cctcactaga   1020

tgcctctgac ccagcctccc ctgggggagt gggtggccac agaccctccc tgccagagct   1080

cctggaaggc tcctgcaggc ctgacccatc tattcctgta gacctggttt aggatgaagt   1140

ctcggtgcga tttttgcaga gttgggttta tctttcaact atagaccctt ctggctgttc   1200

tcagccatat catgtgactc tgaatagttg gatgaggaat ggaaagaaag caaggatgag   1260

agccggtcac gtggcagtct ccgcccagca tcggctgtcc gcacagaggc acagggcagg   1320

cctcctgtgc actccccacc tagcactggc ctgtcctgaa tccccgcctt ccctggttgg   1380

aggccagctg tggcatttgc accctcttct cacctcacca tgcacatgct aactttaaag   1440

ccttggggtc tttcctgtac cccctcctca accctggtcc accccctctc aggatcttgt   1500

caacgttatt tttcctgtcc cgtcttccta tcgctggcct tcctttccca tcctaaaaac   1560

ttgccgaggc cctatggctc cctccctttc tttcccaggc agcttcttat ctgggctgtc   1620

tgtacccctt cctttgcacc acccaccatg ccccacgtag ctgaaagctg cttatcccaa   1680

ttgtcaactc tggccttctt cagcctctgt agcaccagac actgcacctc ctgaatgtcc   1740

tctgcttctc tgcttcagag gcccaggctc gccagttctc tgacctctcc catatgtctg   1800

cttaggactc tgctgcagct gtcctcacca gcctccgggg aatcccacta cccacagggc   1860

agggctgtgg gctgggctga aaaaccatct gcatggtcca caagaagcct ggcactgggt   1920

ttccccatga ataacaatga aaattaatgg atgcac                             1956


<210>  7180
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7180

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7181
<211>  4071
<212>  DNA
<213>  Homo sapiens

<400>  7181
agaagacgtc tctcgttaag gggacagctg caggagtgta ggtgccttgt tctggcctcc     60

gtgtggaggc agtagtgaca aagagggagg caggcctggg gcaggggcga ggctctgtcc    120

tccaggcatt ttgtttctgg tgaccgcccc taatgggata tcggtgatca ctggtccacc    180

cttcctgtca gggcttttct ggggctgctc ttggaaatga agtcttaagt actgaataac    240

tcccctgggg atagctgggg catttgtcta gctgggctac tttctaacac tttgccatag    300

ctcagaccac ttctcatcgt tcagggatgg actgcaacct taatttactt gccggagtgt    360

acattctagt gtggtgtata ctggtggctg ttgatgatga tttttttttt tttacacaat    420

tctctgtaga ctaggagaag aatgcttgtg tttttcggaa gtgtgatgct tctctttgac    480

tgccaaactc ttttatggaa tatatcttta tattaatgct gttttggtca tttttgtttg    540

gggtcactat tgagatattg ctaagcatct cagtggtaaa cgcggctgcc agaggaacca    600

agggataggg tatgtagacc ttacagaagg atggatggta aaggcagtcc atcatcagca    660

caatctgact tacatttcat tgagtaattt tttttttttt taagattctg tatggcagca    720

ctttcagttg cccttgtgtg ccggccacag ccgcacaagt tggcttgtgg tttatccccc    780

gctataagtg agagctggag aaacttcaac tccataggtc tagaggaaac attgttttag    840

gttatttctg tccacccctg tgcgatacta tttattgatc caagcagaag agcttgggga    900

cactgagtcg aagtggggac atgggattga agcctgggca ctgctgctgc atgagctgtg    960

tgtcctgggt gtgccggcct ttctgtgaag ggggttggtg gcagtgccca cctcactaga   1020

tgcctctgac ccagcctccc ctgggggagt gggtggccac agaccctccc tgccagagct   1080

cctggaaggc tcctgcaggc ctgacccatc tattcctgta gacctggttt aggatgaagt   1140

ctcggtgcga tttttgcaga gttgggttta tctttcaact atagaccctt ctggctgttc   1200

tcagccatat catgtgactc tgaatagttg gatgaggaat ggaaagaaag caaggatgag   1260

agccggtcac gtggcagtct ccgcccagca tcggctgtcc gcacagaggc acagggcagg   1320

cctcctgtgc actccccacc tagcactggc ctgtcctgaa tccccgcctt ccctggttgg   1380

aggccagctg tggcatttgc accctcttct cacctcacca tgcacatgct aactttaaag   1440

ccttggggtc tttcctgtac cccctcctca accctggtcc accccctctc aggatcttgt   1500

caacgttatt tttcctgtcc cgtcttccta tcgctggcct tcctttccca tcctaaaaac   1560

ttgccgaggc cctatggctc cctccctttc tttcccaggc agcttcttat ctgggctgtc   1620

tgtacccctt cctttgcacc acccaccatg ccccacgtag ctgaaagctg cttatcccaa   1680

ttgtcaactc tggccttctt cagcctctgt agcaccagac actgcacctc ctgaatgtcc   1740

tctgcttctc tgcttcagag gcccaggctc gccagttctc tgacctctcc catatgtctg   1800

cttaggactc tgctgcagct gtcctcacca gcctccgggg aatcccacta cccacagggc   1860

agggctgtgg gctgggctga aaaaccatct gcatggtcca caagaagcct ggcactgggt   1920

ttccccatga ataacaatga aaattaatgg atgcacaacc ttcctggaac gtggaatttc   1980

tctgggagat tccatgcaga ggccactggg gaggtggcag gcatgcatgt gactgtaggt   2040

ggctgcagtg ttggaaggct cccagcagag cagagagggt gtcagtctca tcagggaacc   2100

cacctgatgg cttctcagcc agcagtctca gaggaacata gacgactgct gagaaaggag   2160

ggaggcagca gtggtcccag cacctgaggc atcctgctgt catgggaagg tctccgccca   2220

aatgtcagat gcatcagcct gtcacccgct ggtccagagc tttcagctgt actggtaggg   2280

ggtgggtggt ggagtgctga atgaccttca caggtgggcc tttccagctc tagggtctta   2340

cgggtgtcgg tccacagaac cacggttttt aggttgtgtg tccggggcta tgggaacctg   2400

tcccccatga tggatcttgg tagagacact tccctctgtc atcgtgccca ggaggatgct   2460

gcaggtgact acctgcagcc ctgttctcat tcatttggat gccctccaga aatctgggga   2520

gccatacacc tttagagcct tttttgctcc ttatcaagtt ggcaaggctt ggccaattcc   2580

tgttcaaggc tgcattaaag gcatgttcac catcctggct aatacggtga aaccccttct   2640

ctactaaaaa tacaaaaaaa ttagccgggc ttggtggcgg gtgcctgtag tcccagctac   2700

tccggaggct gaggcagggg aatggtgtga acccaggagg cggagcttgc agtgagccga   2760

gatcacacca ctgcactcca gcctgggctc aaaaaagaaa aaaaaaaaaa aaaaaaggcc   2820

cgttcattct caaatgcttt tggcgtctcc agggtgcctc aggaaaacat gaagtgggca   2880

ttgtagaact tggggctact gtgtaacttt ggaagaaaaa gttaagggta cttttaagtg   2940

gatactgttt tgatgaaatt gccaacttca gggagcccag cttggagaag gaggacgtga   3000

gtattcctta caaggctccg aaacaattct ttcttcactt agttttcttt ctgtgctctg   3060

catcttatat tccagcaggg tcttccaatg catggtttaa taactactag aactggccag   3120

gtgcagtggc tcacgcctgt aatcccagaa ctttgggagg ctaagacagg cagatcactt   3180

gaggccagga gttcgagacc agcctggaca acatggtgat acccagtttc tactaaaaat   3240

acaaaaatta gtcgggcatg gtgatgtgca cctgtagtcc cagctgctcg ggaggctgag   3300

gcaggagaat cgcttgaacc cgggagacag aggttgcaac gagccaagat cgagccactg   3360

cgctccggcc tgggtgacag gagactccat ctcaaaaaat aaaattaaaa aaaaactact   3420

acaataaatt atcaccttgg actgtataaa acaactttta aactagtctt tttaaaaagt   3480

acacttaaat aaaaatctaa acataagaga atgtaaagtg aaaagtgaaa gtatgtcttc   3540

tgttacgcag aggtaactac tattaggaat ccttcctgaa aatgtccatg catctactca   3600

ggtcatcaca cccatggaat cattttacat actattttat gagtgttact taatatactg   3660

atccacagtg cgttttcacg gtcacgccat cagttgtagg agtgtgccaa gaacagatgg   3720

gccttgcctt tgtaccagag gagtccattt acagttgcag gtaatagaaa acccaattca   3780

gactggccta aacaatgagg ggaggttttg gctcttgaaa ctggaaagtc ccaaggtggg   3840

gtgagtttca ggtttgggtt gatccaagtg gctcagtgac gtcaacagga tcttgtttcc   3900

atttctctgc cttccacagc ctccccttca tctatggtgg agggaaggag tctaccacag   3960

acaaaccccg agcctccccc tgatgggtgg tgtggtggtg aagccagcaa gggaagggat   4020

ccccggacac acccctcctc atgctttatc ccactgaaac catgcggctg t            4071


<210>  7182
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7182

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7183
<211>  2602
<212>  DNA
<213>  Homo sapiens

<400>  7183
attacctctg taaagagcct gtctacaaat acagtcacct tctgaagtcc tgggggttag     60

gacttcagtg tatggatttt gaggacacaa tttagctcct aacacctcta aaattagggg    120

ctaatactcc atcatgttgc catggaggag gctgataggt gtgagggggc tggggccgat    180

tgccctgtgt ggggtgggca gggctggggt gtgtgctggg atggttactg acaccccacc    240

ggggttagca gtggagggag ctggttggct ggcgactgtt gcctgctggc tctgtctcct    300

ggagctgagc ttactggtgg gatgcccgct ccgagaagca cccttcttct cttcttagga    360

gactctggac ccccttctcc aggtttctct ccctttagag gcacattttc ctccaagcct    420

tcaagcccct tctctttctc cagatgtgga tggtggggaa gggtatcttg agaaagttgg    480

gctttaaatc tctggagacc tgaaaggaaa cagccaggga gcctttggtc agacaggtgg    540

tgcgatggca cagtgcccag cgaggggcag aggctgagag gagctgacga gcatctcctg    600

gagagtcctc cttgcctgcc tcctggatcc ctcgttccca ccctgctttg ccctgctcct    660

taccagagct cactagggga tcaggtgggg acatcgtgtg tgccaaaggc tcagacccct    720

gtggtgtttt cctgcagctg aagagcaagt gggatgagtc catcttcacg aaaggctgca    780

tccaggcgct ggaaagctgg ctcccgcgga acatttacat tgtggctggc gtcttcatcg    840

ccatctcgct gttgcagata tttggcatct tcctggcaag gacgctgatc tcagacatcg    900

aggcagtgaa ggccggccat cacttctgag gagcagagtt gagggagccg agctgagcca    960

cgctgggagg ccagagcctt tctctgccat cagccctacg tccagaggga gaggagccga   1020

cacccccaga gccagtgccc catcttaagc atcagcgtga cgtgacctct ctgtttctgc   1080

ttgctggtgc tgaagaccaa gggtccccct tgttacctgc ccaaacttgt gactgcatcc   1140

ctctggagtc tacccagaga cagagaatgt gtctttatgt gggagtggtg actctgaaag   1200

acagagaggg ctcctgtggc tgccaggagg gcttgactca gaccccctgc agctcaagca   1260

tgtctgcagg acaccctggt cccctctcca ctggcatcca gacatctgct ttgggtcatc   1320

cacatctgtg ggtgggccgt gggtagaggg acccacaggc gtggacaggg catctctctc   1380

catcaagcaa agcagcatgg gggcctgccc gtaacgggag gcggacgtgg ccccgctggg   1440

cctctgagtg ccagcgcagt ctgctgggac atgcacatat caggggttgt ttgcaggatc   1500

ctcagccatg ttcaagtgaa gtaagcctga gccagtgcgt ggactggtgc cacgggagtg   1560

ccttgtccac tgtccccctg tgtccaccag ctattctcct ggcgccggaa ctgcctctgg   1620

tcttgatagc attaagccct gatggcgccg gtggcgcggt gggcatggtt cttcactgag   1680

agccggctct ccttttctta aagtgtgtaa atagtttatt tataggggta agaatgttct   1740

cacaccattt cacttcctct tcctctcctc cagcattctc ctctgagcag ccttagatag   1800

tgtccatggc tggagccgac cctttgagtc cccttgagtg tcttaagaac cagcccacaa   1860

cagcctctct ttctcctcca catactgcag cctccctcca tgcatcccac atacaagcac   1920

tcccccactc cccagcgtgg cctcactgtc ttctggtctt ggtgctactg aaattgtcac   1980

ccagaatttg aatcctgacc ctccccactg caagcccagg gagccccagc ccaagatggc   2040

cagcctgaaa ctgttggcca gggctcctct tgtggccatg tacccagggc tggctggcct   2100

gccatttgcc tctccccgga gacagccgtt cttctgcaac cacaccccgt gcctagccac   2160

aaccccaggc tgcagctgct cagaagctcc aggcattttg tttctggtga ccgcccctaa   2220

tgggatatcg gtgatcactg gtccaccctt cctgtcaggg cttttctggg gctgctcttg   2280

gaaatgaagt cttaagtact gaataactcc cctggggata gctggggcat ttgtctagct   2340

gggctacttt ctaacacttt gccatagctc agaccacttc tcatcgttca gggatggact   2400

gcaaccttaa tttacttgcc ggagtgtaca ttctagtgtg gtgtatactg gtggctgttg   2460

atgatgattt tttttttttt acacaattct ctgtagacta ggagaagaat gcttgtgttt   2520

ttcggaagtg tgatgcttct ctttgactgc caaactcttt tatggaatat atctttatat   2580

taatgctgtt ttggtcattt tt                                            2602


<210>  7184
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  7184

Met Ser Pro Ser Ser Arg Lys Ala Ala Ser Arg Arg Trp Lys Ala Gly 
1               5                   10                  15


Ser Arg Gly Thr Phe Thr Leu Trp Leu Ala Ser Ser Ser Pro Ser Arg 
            20                  25                  30


Cys Cys Arg Tyr Leu Ala Ser Ser Trp Gln Gly Arg 
        35                  40


<210>  7185
<211>  729
<212>  DNA
<213>  Homo sapiens

<400>  7185
ggggttagga cttcagtgta tggattttga ggacacaatt tagctcctaa cacctctaaa     60

attaggggct aatactccat catgttgcca tggaggaggc tgataggtgt gagggggctg    120

gggccgattg cccactgcaa gcccagggag ccccagccca agatggccag cctgaaactg    180

ttggccaggg ctcctcttgt ggccatgtac ccagggctgg ctggcctgcc atttgcctct    240

ccccggagac agccgttctt ctgcaaccac accccgtgcc tagccacaac cccaggctgc    300

agctgctcag aagctccagg cattttgttt ctggtgaccg cccctaatgg gatatcggtg    360

atcactggtc cacccttcct gtcagggctt ttctggggct gctcttggaa atgaagtctt    420

aagtactgaa taactcccct ggggatagct ggggcatttg tctagctggg ctactttcta    480

acactttgcc atagctcaga ccacttctca tcgttcaggg atggactgca accttaattt    540

acttgccgga gtgtacattc tagtgtggtg tatactggtg gctgttgatg atgatttttt    600

tttttttaca caattctctg tagactagga gaagaatgct tgtgtttttc ggaagtgtga    660

tgcttctctt tgactgccaa actcttttat ggaatatatc tttatattaa tgctgttttg    720

gtcattttt                                                            729


<210>  7186
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  7186

Met Leu Pro Trp Arg Arg Leu Ile Gly Val Arg Gly Leu Gly Pro Ile 
1               5                   10                  15


Ala His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu Lys 
            20                  25                  30


Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala Gly 
        35                  40                  45


Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His Thr 
    50                  55                  60


Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro Gly 
65                  70                  75                  80


Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr Gly 
                85                  90                  95


Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
            100                 105                 110


<210>  7187
<211>  2098
<212>  DNA
<213>  Homo sapiens

<400>  7187
cctctaaaat taggggctaa tactccatca tgttgccatg gaggaggctg ataggtgtga     60

gggggctggg gccgattgcc cactgcaagc ccagggagcc ccagcccaag atggccagcc    120

tgaaactgtt ggccagggct cctcttgtgg ccatgtaccc agggctggct ggcctgccat    180

ttgcctctcc ccggagacag ccgttcttct gcaaccacac cccgtgccta gccacaaccc    240

caggctgcag ctgctcagaa gctccaggca ttttgtttct ggtgaccgcc cctaatggga    300

tatcggtgat cactggtcca cccttcctgt cagggctttt ctggggctgc tcttggaaat    360

gaagtcttaa gtactgaata actcccctgg ggatagctgg ggcatttgtc tagctgggct    420

actttctaac actttgccat agctcagacc acttctcatc gttcagggat ggactgcaac    480

cttaatttac ttgccggagt gtacattcta gtgtggtgta tactggtggc tgttgatgat    540

gatttttttt tttttacaca attctctgta gactaggaga agaatgcttg tgtttttcgg    600

aagtgtgatg cttctctttg actgccaaac tcttttatgg aatatatctt tatattaatg    660

ctgttttggt catttttgtt tggggtcact attgagatat tgctaagcat ctcagtggta    720

aacgcggctg ccagaggaac caagggatag ggtatgtaga ccttacagaa ggatggatgg    780

taaaggcagt ccatcatcag cacaatctga cttacatttc attgagtaat tttttttttt    840

tttaagattc tgtatggcag cactttcagt tgcccttgtg tgccggccac agccgcacaa    900

gttggcttgt ggtttatccc ccgctataag tgagagctgg agaaacttca actccatagg    960

tctagaggaa acattgtttt aggttatttc tgtccacccc tgtgcgatac tatttattga   1020

tccaagcaga agagcttggg gacactgagt cgaagtgggg acatgggatt gaagcctggg   1080

cactgctgct gcatgagctg tgtgtcctgg gtgtgccggc ctttctgtga agggggttgg   1140

tggcagtgcc cacctcacta gatgcctctg acccagcctc ccctggggga gtgggtggcc   1200

acagaccctc cctgccagag ctcctggaag gctcctgcag gcctgaccca tctattcctg   1260

tagacctggt ttaggatgaa gtctcggtgc gatttttgca gagttgggtt tatctttcaa   1320

ctatagaccc ttctggctgt tctcagccat atcatgtgac tctgaatagt tggatgagga   1380

atggaaagaa agcaaggatg agagccggtc acgtggcagt ctccgcccag catcggctgt   1440

ccgcacagag gcacagggca ggcctcctgt gcactcccca cctagcactg gcctgtcctg   1500

aatccccgcc ttccctggtt ggaggccagc tgtggcattt gcaccctctt ctcacctcac   1560

catgcacatg ctaactttaa agccttgggg tctttcctgt accccctcct caaccctggt   1620

ccaccccctc tcaggatctt gtcaacgtta tttttcctgt cccgtcttcc tatcgctggc   1680

cttcctttcc catcctaaaa acttgccgag gccctatggc tccctccctt tctttcccag   1740

gcagcttctt atctgggctg tctgtacccc ttcctttgca ccacccacca tgccccacgt   1800

agctgaaagc tgcttatccc aattgtcaac tctggccttc ttcagcctct gtagcaccag   1860

acactgcacc tcctgaatgt cctctgcttc tctgcttcag aggcccaggc tcgccagttc   1920

tctgacctct cccatatgtc tgcttaggac tctgctgcag ctgtcctcac cagcctccgg   1980

ggaatcccac tacccacagg gcagggctgt gggctgggct gaaaaaccat ctgcatggtc   2040

cacaagaagc ctggcactgg gtttccccat gaataacaat gaaaattaat ggatgcac     2098


<210>  7188
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  7188

Met Leu Pro Trp Arg Arg Leu Ile Gly Val Arg Gly Leu Gly Pro Ile 
1               5                   10                  15


Ala His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu Lys 
            20                  25                  30


Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala Gly 
        35                  40                  45


Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His Thr 
    50                  55                  60


Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro Gly 
65                  70                  75                  80


Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr Gly 
                85                  90                  95


Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
            100                 105                 110


<210>  7189
<211>  4213
<212>  DNA
<213>  Homo sapiens

<400>  7189
cctctaaaat taggggctaa tactccatca tgttgccatg gaggaggctg ataggtgtga     60

gggggctggg gccgattgcc cactgcaagc ccagggagcc ccagcccaag atggccagcc    120

tgaaactgtt ggccagggct cctcttgtgg ccatgtaccc agggctggct ggcctgccat    180

ttgcctctcc ccggagacag ccgttcttct gcaaccacac cccgtgccta gccacaaccc    240

caggctgcag ctgctcagaa gctccaggca ttttgtttct ggtgaccgcc cctaatggga    300

tatcggtgat cactggtcca cccttcctgt cagggctttt ctggggctgc tcttggaaat    360

gaagtcttaa gtactgaata actcccctgg ggatagctgg ggcatttgtc tagctgggct    420

actttctaac actttgccat agctcagacc acttctcatc gttcagggat ggactgcaac    480

cttaatttac ttgccggagt gtacattcta gtgtggtgta tactggtggc tgttgatgat    540

gatttttttt tttttacaca attctctgta gactaggaga agaatgcttg tgtttttcgg    600

aagtgtgatg cttctctttg actgccaaac tcttttatgg aatatatctt tatattaatg    660

ctgttttggt catttttgtt tggggtcact attgagatat tgctaagcat ctcagtggta    720

aacgcggctg ccagaggaac caagggatag ggtatgtaga ccttacagaa ggatggatgg    780

taaaggcagt ccatcatcag cacaatctga cttacatttc attgagtaat tttttttttt    840

tttaagattc tgtatggcag cactttcagt tgcccttgtg tgccggccac agccgcacaa    900

gttggcttgt ggtttatccc ccgctataag tgagagctgg agaaacttca actccatagg    960

tctagaggaa acattgtttt aggttatttc tgtccacccc tgtgcgatac tatttattga   1020

tccaagcaga agagcttggg gacactgagt cgaagtgggg acatgggatt gaagcctggg   1080

cactgctgct gcatgagctg tgtgtcctgg gtgtgccggc ctttctgtga agggggttgg   1140

tggcagtgcc cacctcacta gatgcctctg acccagcctc ccctggggga gtgggtggcc   1200

acagaccctc cctgccagag ctcctggaag gctcctgcag gcctgaccca tctattcctg   1260

tagacctggt ttaggatgaa gtctcggtgc gatttttgca gagttgggtt tatctttcaa   1320

ctatagaccc ttctggctgt tctcagccat atcatgtgac tctgaatagt tggatgagga   1380

atggaaagaa agcaaggatg agagccggtc acgtggcagt ctccgcccag catcggctgt   1440

ccgcacagag gcacagggca ggcctcctgt gcactcccca cctagcactg gcctgtcctg   1500

aatccccgcc ttccctggtt ggaggccagc tgtggcattt gcaccctctt ctcacctcac   1560

catgcacatg ctaactttaa agccttgggg tctttcctgt accccctcct caaccctggt   1620

ccaccccctc tcaggatctt gtcaacgtta tttttcctgt cccgtcttcc tatcgctggc   1680

cttcctttcc catcctaaaa acttgccgag gccctatggc tccctccctt tctttcccag   1740

gcagcttctt atctgggctg tctgtacccc ttcctttgca ccacccacca tgccccacgt   1800

agctgaaagc tgcttatccc aattgtcaac tctggccttc ttcagcctct gtagcaccag   1860

acactgcacc tcctgaatgt cctctgcttc tctgcttcag aggcccaggc tcgccagttc   1920

tctgacctct cccatatgtc tgcttaggac tctgctgcag ctgtcctcac cagcctccgg   1980

ggaatcccac tacccacagg gcagggctgt gggctgggct gaaaaaccat ctgcatggtc   2040

cacaagaagc ctggcactgg gtttccccat gaataacaat gaaaattaat ggatgcacaa   2100

ccttcctgga acgtggaatt tctctgggag attccatgca gaggccactg gggaggtggc   2160

aggcatgcat gtgactgtag gtggctgcag tgttggaagg ctcccagcag agcagagagg   2220

gtgtcagtct catcagggaa cccacctgat ggcttctcag ccagcagtct cagaggaaca   2280

tagacgactg ctgagaaagg agggaggcag cagtggtccc agcacctgag gcatcctgct   2340

gtcatgggaa ggtctccgcc caaatgtcag atgcatcagc ctgtcacccg ctggtccaga   2400

gctttcagct gtactggtag ggggtgggtg gtggagtgct gaatgacctt cacaggtggg   2460

cctttccagc tctagggtct tacgggtgtc ggtccacaga accacggttt ttaggttgtg   2520

tgtccggggc tatgggaacc tgtcccccat gatggatctt ggtagagaca cttccctctg   2580

tcatcgtgcc caggaggatg ctgcaggtga ctacctgcag ccctgttctc attcatttgg   2640

atgccctcca gaaatctggg gagccataca cctttagagc cttttttgct ccttatcaag   2700

ttggcaaggc ttggccaatt cctgttcaag gctgcattaa aggcatgttc accatcctgg   2760

ctaatacggt gaaacccctt ctctactaaa aatacaaaaa aattagccgg gcttggtggc   2820

gggtgcctgt agtcccagct actccggagg ctgaggcagg ggaatggtgt gaacccagga   2880

ggcggagctt gcagtgagcc gagatcacac cactgcactc cagcctgggc tcaaaaaaga   2940

aaaaaaaaaa aaaaaaaagg cccgttcatt ctcaaatgct tttggcgtct ccagggtgcc   3000

tcaggaaaac atgaagtggg cattgtagaa cttggggcta ctgtgtaact ttggaagaaa   3060

aagttaaggg tacttttaag tggatactgt tttgatgaaa ttgccaactt cagggagccc   3120

agcttggaga aggaggacgt gagtattcct tacaaggctc cgaaacaatt ctttcttcac   3180

ttagttttct ttctgtgctc tgcatcttat attccagcag ggtcttccaa tgcatggttt   3240

aataactact agaactggcc aggtgcagtg gctcacgcct gtaatcccag aactttggga   3300

ggctaagaca ggcagatcac ttgaggccag gagttcgaga ccagcctgga caacatggtg   3360

atacccagtt tctactaaaa atacaaaaat tagtcgggca tggtgatgtg cacctgtagt   3420

cccagctgct cgggaggctg aggcaggaga atcgcttgaa cccgggagac agaggttgca   3480

acgagccaag atcgagccac tgcgctccgg cctgggtgac aggagactcc atctcaaaaa   3540

ataaaattaa aaaaaaacta ctacaataaa ttatcacctt ggactgtata aaacaacttt   3600

taaactagtc tttttaaaaa gtacacttaa ataaaaatct aaacataaga gaatgtaaag   3660

tgaaaagtga aagtatgtct tctgttacgc agaggtaact actattagga atccttcctg   3720

aaaatgtcca tgcatctact caggtcatca cacccatgga atcattttac atactatttt   3780

atgagtgtta cttaatatac tgatccacag tgcgttttca cggtcacgcc atcagttgta   3840

ggagtgtgcc aagaacagat gggccttgcc tttgtaccag aggagtccat ttacagttgc   3900

aggtaataga aaacccaatt cagactggcc taaacaatga ggggaggttt tggctcttga   3960

aactggaaag tcccaaggtg gggtgagttt caggtttggg ttgatccaag tggctcagtg   4020

acgtcaacag gatcttgttt ccatttctct gccttccaca gcctcccctt catctatggt   4080

ggagggaagg agtctaccac agacaaaccc cgagcctccc cctgatgggt ggtgtggtgg   4140

tgaagccagc aagggaaggg atccccggac acacccctcc tcatgcttta tcccactgaa   4200

accatgcggc tgt                                                      4213


<210>  7190
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  7190

Met Leu Pro Trp Arg Arg Leu Ile Gly Val Arg Gly Leu Gly Pro Ile 
1               5                   10                  15


Ala His Cys Lys Pro Arg Glu Pro Gln Pro Lys Met Ala Ser Leu Lys 
            20                  25                  30


Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr Pro Gly Leu Ala Gly 
        35                  40                  45


Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe Phe Cys Asn His Thr 
    50                  55                  60


Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys Ser Glu Ala Pro Gly 
65                  70                  75                  80


Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile Ser Val Ile Thr Gly 
                85                  90                  95


Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys Ser Trp Lys 
            100                 105                 110


<210>  7191
<211>  1666
<212>  DNA
<213>  Homo sapiens

<400>  7191
gcccgctccg agaagcaccc ttcttctctt cttaggagac tctggacccc cttctccagg     60

tttctctccc tttagaggca cattttcctc caaagccagt gccccatctt aagcatcagc    120

gtgacgtgac ctctctgttt ctgcttgctg gtgctgaaga ccaagggtcc cccttgttac    180

ctgcccaaac ttgtgactgc atccctctgg agtctaccca gagacagaga atgtgtcttt    240

atgtgggagt ggtgactctg aaagacagag agggctcctg tggctgccag gagggcttga    300

ctcagacccc ctgcagctca agcatgtctg caggacaccc tggtcccctc tccactggca    360

tccagacatc tgctttgggt catccacatc tgtgggtggg ccgtgggtag agggacccac    420

aggcgtggac agggcatctc tctccatcaa gcaaagcagc atgggggcct gcccgtaacg    480

ggaggcggac gtggccccgc tgggcctctg agtgccagcg cagtctgctg ggacatgcac    540

atatcagggg ttgtttgcag gatcctcagc catgttcaag tgaagtaagc ctgagccagt    600

gcgtggactg gtgccacggg agtgccttgt ccactgtccc cctgtgtcca ccagctattc    660

tcctggcgcc ggaactgcct ctggtcttga tagcattaag ccctgatggc gccggtggcg    720

cggtgggcat ggttcttcac tgagagccgg ctctcctttt cttaaagtgt gtaaatagtt    780

tatttatagg ggtaagaatg ttctcacacc atttcacttc ctcttcctct cctccagcat    840

tctcctctga gcagccttag atagtgtcca tggctggagc cgaccctttg agtccccttg    900

agtgtcttaa gaaccagccc acaacagcct ctctttctcc tccacatact gcagcctccc    960

tccatgcatc ccacatacaa gcactccccc actccccagc gtggcctcac tgtcttctgg   1020

tcttggtgct actgaaattg tcacccagaa tttgaatcct gaccctcccc actgcaagcc   1080

cagggagccc cagcccaaga tggccagcct gaaactgttg gccagggctc ctcttgtggc   1140

catgtaccca gggctggctg gcctgccatt tgcctctccc cggagacagc cgttcttctg   1200

caaccacacc ccgtgcctag ccacaacccc aggctgcagc tgctcagaag ctccaggcat   1260

tttgtttctg gtgaccgccc ctaatgggat atcggtgatc actggtccac ccttcctgtc   1320

agggcttttc tggggctgct cttggaaatg aagtcttaag tactgaataa ctcccctggg   1380

gatagctggg gcatttgtct agctgggcta ctttctaaca ctttgccata gctcagacca   1440

cttctcatcg ttcagggatg gactgcaacc ttaatttact tgccggagtg tacattctag   1500

tgtggtgtat actggtggct gttgatgatg attttttttt ttttacacaa ttctctgtag   1560

actaggagaa gaatgcttgt gtttttcgga agtgtgatgc ttctctttga ctgccaaact   1620

cttttatgga atatatcttt atattaatgc tgttttggtc attttt                  1666


<210>  7192
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  7192

Met Ala Ser Leu Lys Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr 
1               5                   10                  15


Pro Gly Leu Ala Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe 
            20                  25                  30


Phe Cys Asn His Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys 
        35                  40                  45


Ser Glu Ala Pro Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile 
    50                  55                  60


Ser Val Ile Thr Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys 
65                  70                  75                  80


Ser Trp Lys 



<210>  7193
<211>  3087
<212>  DNA
<213>  Homo sapiens

<400>  7193
gcccgctccg agaagcaccc ttcttctctt cttaggagac tctggacccc cttctccagg     60

tttctctccc tttagaggca cattttcctc caaagccagt gccccatctt aagcatcagc    120

gtgacgtgac ctctctgttt ctgcttgctg gtgctgaaga ccaagggtcc cccttgttac    180

ctgcccaaac ttgtgactgc atccctctgg agtctaccca gagacagaga atgtgtcttt    240

atgtgggagt ggtgactctg aaagacagag agggctcctg tggctgccag gagggcttga    300

ctcagacccc ctgcagctca agcatgtctg caggacaccc tggtcccctc tccactggca    360

tccagacatc tgctttgggt catccacatc tgtgggtggg ccgtgggtag agggacccac    420

aggcgtggac agggcatctc tctccatcaa gcaaagcagc atgggggcct gcccgtaacg    480

ggaggcggac gtggccccgc tgggcctctg agtgccagcg cagtctgctg ggacatgcac    540

atatcagggg ttgtttgcag gatcctcagc catgttcaag tgaagtaagc ctgagccagt    600

gcgtggactg gtgccacggg agtgccttgt ccactgtccc cctgtgtcca ccagctattc    660

tcctggcgcc ggaactgcct ctggtcttga tagcattaag ccctgatggc gccggtggcg    720

cggtgggcat ggttcttcac tgagagccgg ctctcctttt cttaaagtgt gtaaatagtt    780

tatttatagg ggtaagaatg ttctcacacc atttcacttc ctcttcctct cctccagcat    840

tctcctctga gcagccttag atagtgtcca tggctggagc cgaccctttg agtccccttg    900

agtgtcttaa gaaccagccc acaacagcct ctctttctcc tccacatact gcagcctccc    960

tccatgcatc ccacatacaa gcactccccc actccccagc gtggcctcac tgtcttctgg   1020

tcttggtgct actgaaattg tcacccagaa tttgaatcct gaccctcccc actgcaagcc   1080

cagggagccc cagcccaaga tggccagcct gaaactgttg gccagggctc ctcttgtggc   1140

catgtaccca gggctggctg gcctgccatt tgcctctccc cggagacagc cgttcttctg   1200

caaccacacc ccgtgcctag ccacaacccc aggctgcagc tgctcagaag ctccaggcat   1260

tttgtttctg gtgaccgccc ctaatgggat atcggtgatc actggtccac ccttcctgtc   1320

agggcttttc tggggctgct cttggaaatg aagtcttaag tactgaataa ctcccctggg   1380

gatagctggg gcatttgtct agctgggcta ctttctaaca ctttgccata gctcagacca   1440

cttctcatcg ttcagggatg gactgcaacc ttaatttact tgccggagtg tacattctag   1500

tgtggtgtat actggtggct gttgatgatg attttttttt ttttacacaa ttctctgtag   1560

actaggagaa gaatgcttgt gtttttcgga agtgtgatgc ttctctttga ctgccaaact   1620

cttttatgga atatatcttt atattaatgc tgttttggtc atttttgttt ggggtcacta   1680

ttgagatatt gctaagcatc tcagtggtaa acgcggctgc cagaggaacc aagggatagg   1740

gtatgtagac cttacagaag gatggatggt aaaggcagtc catcatcagc acaatctgac   1800

ttacatttca ttgagtaatt tttttttttt ttaagattct gtatggcagc actttcagtt   1860

gcccttgtgt gccggccaca gccgcacaag ttggcttgtg gtttatcccc cgctataagt   1920

gagagctgga gaaacttcaa ctccataggt ctagaggaaa cattgtttta ggttatttct   1980

gtccacccct gtgcgatact atttattgat ccaagcagaa gagcttgggg acactgagtc   2040

gaagtgggga catgggattg aagcctgggc actgctgctg catgagctgt gtgtcctggg   2100

tgtgccggcc tttctgtgaa gggggttggt ggcagtgccc acctcactag atgcctctga   2160

cccagcctcc cctgggggag tgggtggcca cagaccctcc ctgccagagc tcctggaagg   2220

ctcctgcagg cctgacccat ctattcctgt agacctggtt taggatgaag tctcggtgcg   2280

atttttgcag agttgggttt atctttcaac tatagaccct tctggctgtt ctcagccata   2340

tcatgtgact ctgaatagtt ggatgaggaa tggaaagaaa gcaaggatga gagccggtca   2400

cgtggcagtc tccgcccagc atcggctgtc cgcacagagg cacagggcag gcctcctgtg   2460

cactccccac ctagcactgg cctgtcctga atccccgcct tccctggttg gaggccagct   2520

gtggcatttg caccctcttc tcacctcacc atgcacatgc taactttaaa gccttggggt   2580

ctttcctgta ccccctcctc aaccctggtc caccccctct caggatcttg tcaacgttat   2640

ttttcctgtc ccgtcttcct atcgctggcc ttcctttccc atcctaaaaa cttgccgagg   2700

ccctatggct ccctcccttt ctttcccagg cagcttctta tctgggctgt ctgtacccct   2760

tcctttgcac cacccaccat gccccacgta gctgaaagct gcttatccca attgtcaact   2820

ctggccttct tcagcctctg tagcaccaga cactgcacct cctgaatgtc ctctgcttct   2880

ctgcttcaga ggcccaggct cgccagttct ctgacctctc ccatatgtct gcttaggact   2940

ctgctgcagc tgtcctcacc agcctccggg gaatcccact acccacaggg cagggctgtg   3000

ggctgggctg aaaaaccatc tgcatggtcc acaagaagcc tggcactggg tttccccatg   3060

aataacaatg aaaattaatg gatgcac                                       3087


<210>  7194
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7194

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7195
<211>  5202
<212>  DNA
<213>  Homo sapiens

<400>  7195
gcccgctccg agaagcaccc ttcttctctt cttaggagac tctggacccc cttctccagg     60

tttctctccc tttagaggca cattttcctc caaagccagt gccccatctt aagcatcagc    120

gtgacgtgac ctctctgttt ctgcttgctg gtgctgaaga ccaagggtcc cccttgttac    180

ctgcccaaac ttgtgactgc atccctctgg agtctaccca gagacagaga atgtgtcttt    240

atgtgggagt ggtgactctg aaagacagag agggctcctg tggctgccag gagggcttga    300

ctcagacccc ctgcagctca agcatgtctg caggacaccc tggtcccctc tccactggca    360

tccagacatc tgctttgggt catccacatc tgtgggtggg ccgtgggtag agggacccac    420

aggcgtggac agggcatctc tctccatcaa gcaaagcagc atgggggcct gcccgtaacg    480

ggaggcggac gtggccccgc tgggcctctg agtgccagcg cagtctgctg ggacatgcac    540

atatcagggg ttgtttgcag gatcctcagc catgttcaag tgaagtaagc ctgagccagt    600

gcgtggactg gtgccacggg agtgccttgt ccactgtccc cctgtgtcca ccagctattc    660

tcctggcgcc ggaactgcct ctggtcttga tagcattaag ccctgatggc gccggtggcg    720

cggtgggcat ggttcttcac tgagagccgg ctctcctttt cttaaagtgt gtaaatagtt    780

tatttatagg ggtaagaatg ttctcacacc atttcacttc ctcttcctct cctccagcat    840

tctcctctga gcagccttag atagtgtcca tggctggagc cgaccctttg agtccccttg    900

agtgtcttaa gaaccagccc acaacagcct ctctttctcc tccacatact gcagcctccc    960

tccatgcatc ccacatacaa gcactccccc actccccagc gtggcctcac tgtcttctgg   1020

tcttggtgct actgaaattg tcacccagaa tttgaatcct gaccctcccc actgcaagcc   1080

cagggagccc cagcccaaga tggccagcct gaaactgttg gccagggctc ctcttgtggc   1140

catgtaccca gggctggctg gcctgccatt tgcctctccc cggagacagc cgttcttctg   1200

caaccacacc ccgtgcctag ccacaacccc aggctgcagc tgctcagaag ctccaggcat   1260

tttgtttctg gtgaccgccc ctaatgggat atcggtgatc actggtccac ccttcctgtc   1320

agggcttttc tggggctgct cttggaaatg aagtcttaag tactgaataa ctcccctggg   1380

gatagctggg gcatttgtct agctgggcta ctttctaaca ctttgccata gctcagacca   1440

cttctcatcg ttcagggatg gactgcaacc ttaatttact tgccggagtg tacattctag   1500

tgtggtgtat actggtggct gttgatgatg attttttttt ttttacacaa ttctctgtag   1560

actaggagaa gaatgcttgt gtttttcgga agtgtgatgc ttctctttga ctgccaaact   1620

cttttatgga atatatcttt atattaatgc tgttttggtc atttttgttt ggggtcacta   1680

ttgagatatt gctaagcatc tcagtggtaa acgcggctgc cagaggaacc aagggatagg   1740

gtatgtagac cttacagaag gatggatggt aaaggcagtc catcatcagc acaatctgac   1800

ttacatttca ttgagtaatt tttttttttt ttaagattct gtatggcagc actttcagtt   1860

gcccttgtgt gccggccaca gccgcacaag ttggcttgtg gtttatcccc cgctataagt   1920

gagagctgga gaaacttcaa ctccataggt ctagaggaaa cattgtttta ggttatttct   1980

gtccacccct gtgcgatact atttattgat ccaagcagaa gagcttgggg acactgagtc   2040

gaagtgggga catgggattg aagcctgggc actgctgctg catgagctgt gtgtcctggg   2100

tgtgccggcc tttctgtgaa gggggttggt ggcagtgccc acctcactag atgcctctga   2160

cccagcctcc cctgggggag tgggtggcca cagaccctcc ctgccagagc tcctggaagg   2220

ctcctgcagg cctgacccat ctattcctgt agacctggtt taggatgaag tctcggtgcg   2280

atttttgcag agttgggttt atctttcaac tatagaccct tctggctgtt ctcagccata   2340

tcatgtgact ctgaatagtt ggatgaggaa tggaaagaaa gcaaggatga gagccggtca   2400

cgtggcagtc tccgcccagc atcggctgtc cgcacagagg cacagggcag gcctcctgtg   2460

cactccccac ctagcactgg cctgtcctga atccccgcct tccctggttg gaggccagct   2520

gtggcatttg caccctcttc tcacctcacc atgcacatgc taactttaaa gccttggggt   2580

ctttcctgta ccccctcctc aaccctggtc caccccctct caggatcttg tcaacgttat   2640

ttttcctgtc ccgtcttcct atcgctggcc ttcctttccc atcctaaaaa cttgccgagg   2700

ccctatggct ccctcccttt ctttcccagg cagcttctta tctgggctgt ctgtacccct   2760

tcctttgcac cacccaccat gccccacgta gctgaaagct gcttatccca attgtcaact   2820

ctggccttct tcagcctctg tagcaccaga cactgcacct cctgaatgtc ctctgcttct   2880

ctgcttcaga ggcccaggct cgccagttct ctgacctctc ccatatgtct gcttaggact   2940

ctgctgcagc tgtcctcacc agcctccggg gaatcccact acccacaggg cagggctgtg   3000

ggctgggctg aaaaaccatc tgcatggtcc acaagaagcc tggcactggg tttccccatg   3060

aataacaatg aaaattaatg gatgcacaac cttcctggaa cgtggaattt ctctgggaga   3120

ttccatgcag aggccactgg ggaggtggca ggcatgcatg tgactgtagg tggctgcagt   3180

gttggaaggc tcccagcaga gcagagaggg tgtcagtctc atcagggaac ccacctgatg   3240

gcttctcagc cagcagtctc agaggaacat agacgactgc tgagaaagga gggaggcagc   3300

agtggtccca gcacctgagg catcctgctg tcatgggaag gtctccgccc aaatgtcaga   3360

tgcatcagcc tgtcacccgc tggtccagag ctttcagctg tactggtagg gggtgggtgg   3420

tggagtgctg aatgaccttc acaggtgggc ctttccagct ctagggtctt acgggtgtcg   3480

gtccacagaa ccacggtttt taggttgtgt gtccggggct atgggaacct gtcccccatg   3540

atggatcttg gtagagacac ttccctctgt catcgtgccc aggaggatgc tgcaggtgac   3600

tacctgcagc cctgttctca ttcatttgga tgccctccag aaatctgggg agccatacac   3660

ctttagagcc ttttttgctc cttatcaagt tggcaaggct tggccaattc ctgttcaagg   3720

ctgcattaaa ggcatgttca ccatcctggc taatacggtg aaaccccttc tctactaaaa   3780

atacaaaaaa attagccggg cttggtggcg ggtgcctgta gtcccagcta ctccggaggc   3840

tgaggcaggg gaatggtgtg aacccaggag gcggagcttg cagtgagccg agatcacacc   3900

actgcactcc agcctgggct caaaaaagaa aaaaaaaaaa aaaaaaaggc ccgttcattc   3960

tcaaatgctt ttggcgtctc cagggtgcct caggaaaaca tgaagtgggc attgtagaac   4020

ttggggctac tgtgtaactt tggaagaaaa agttaagggt acttttaagt ggatactgtt   4080

ttgatgaaat tgccaacttc agggagccca gcttggagaa ggaggacgtg agtattcctt   4140

acaaggctcc gaaacaattc tttcttcact tagttttctt tctgtgctct gcatcttata   4200

ttccagcagg gtcttccaat gcatggttta ataactacta gaactggcca ggtgcagtgg   4260

ctcacgcctg taatcccaga actttgggag gctaagacag gcagatcact tgaggccagg   4320

agttcgagac cagcctggac aacatggtga tacccagttt ctactaaaaa tacaaaaatt   4380

agtcgggcat ggtgatgtgc acctgtagtc ccagctgctc gggaggctga ggcaggagaa   4440

tcgcttgaac ccgggagaca gaggttgcaa cgagccaaga tcgagccact gcgctccggc   4500

ctgggtgaca ggagactcca tctcaaaaaa taaaattaaa aaaaaactac tacaataaat   4560

tatcaccttg gactgtataa aacaactttt aaactagtct ttttaaaaag tacacttaaa   4620

taaaaatcta aacataagag aatgtaaagt gaaaagtgaa agtatgtctt ctgttacgca   4680

gaggtaacta ctattaggaa tccttcctga aaatgtccat gcatctactc aggtcatcac   4740

acccatggaa tcattttaca tactatttta tgagtgttac ttaatatact gatccacagt   4800

gcgttttcac ggtcacgcca tcagttgtag gagtgtgcca agaacagatg ggccttgcct   4860

ttgtaccaga ggagtccatt tacagttgca ggtaatagaa aacccaattc agactggcct   4920

aaacaatgag gggaggtttt ggctcttgaa actggaaagt cccaaggtgg ggtgagtttc   4980

aggtttgggt tgatccaagt ggctcagtga cgtcaacagg atcttgtttc catttctctg   5040

ccttccacag cctccccttc atctatggtg gagggaagga gtctaccaca gacaaacccc   5100

gagcctcccc ctgatgggtg gtgtggtggt gaagccagca agggaaggga tccccggaca   5160

cacccctcct catgctttat cccactgaaa ccatgcggct gt                      5202


<210>  7196
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7196

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7197
<211>  3425
<212>  DNA
<213>  Homo sapiens

<400>  7197
tggagagtcc tccttgcctg cctcctggat ccctcgttcc caccctgctt tgccctgctc     60

cttaccagag ctcactaggg gatcaggtgg ggacatcgtg tgtgccaaag gctcagaccc    120

ctgtggtgtt ttcctgcagc tgaagagcaa gtgggatgag tccatcttca cgaaaggctg    180

catccaggcg ctggaaagct ggctcccgcg gaacatttac attgtggctg gcgtcttcat    240

cgccatctcg ctgttgcaga tatttggcat cttcctggca aggacgctga tctcagacat    300

cgaggcagtg aaggccggcc atcacttctg aggagcagag ttgagggagc cgagctgagc    360

cacgctggga ggccagagcc tttctctgcc atcagcccta cgtccagagg gagaggagcc    420

gacaccccca gagccagtgc cccatcttaa gcatcagcgt gacgtgacct ctctgtttct    480

gcttgctggt gctgaagacc aagggtcccc cttgttacct gcccaaactt gtgactgcat    540

ccctctggag tctacccaga gacagagaat gtgtctttat gtgggagtgg tgactctgaa    600

agacagagag ggctcctgtg gctgccagga gggcttgact cagaccccct gcagctcaag    660

catgtctgca ggacaccctg gtcccctctc cactggcatc cagacatctg ctttgggtca    720

tccacatctg tgggtgggcc gtgggtagag ggacccacag gcgtggacag ggcatctctc    780

tccatcaagc aaagcagcat gggggcctgc ccgtaacggg aggcggacgt ggccccgctg    840

ggcctctgag tgccagcgca gtctgctggg acatgcacat atcaggggtt gtttgcagga    900

tcctcagcca tgttcaagtg aagtaagcct gagccagtgc gtggactggt gccacgggag    960

tgccttgtcc actgtccccc tgtgtccacc agctattctc ctggcgccgg aactgcctct   1020

ggtcttgata gcattaagcc ctgatggcgc cggtggcgcg gtgggcatgg ttcttcactg   1080

agagccggct ctccttttct taaagtgtgt aaatagttta tttatagggg taagaatgtt   1140

ctcacaccat ttcacttcct cttcctctcc tccagcattc tcctctgagc agccttagat   1200

agtgtccatg gctggagccg accctttgag tccccttgag tgtcttaaga accagcccac   1260

aacagcctct ctttctcctc cacatactgc agcctccctc catgcatccc acatacaagc   1320

actcccccac tccccagcgt ggcctcactg tcttctggtc ttggtgctac tgaaattgtc   1380

acccagaatt tgaatcctga ccctccccac tgcaagccca gggagcccca gcccaagatg   1440

gccagcctga aactgttggc cagggctcct cttgtggcca tgtacccagg gctggctggc   1500

ctgccatttg cctctccccg gagacagccg ttcttctgca accacacccc gtgcctagcc   1560

acaaccccag gctgcagctg ctcagaagct ccaggcattt tgtttctggt gaccgcccct   1620

aatgggatat cggtgatcac tggtccaccc ttcctgtcag ggcttttctg gggctgctct   1680

tggaaatgaa gtcttaagta ctgaataact cccctgggga tagctggggc atttgtctag   1740

ctgggctact ttctaacact ttgccatagc tcagaccact tctcatcgtt cagggatgga   1800

ctgcaacctt aatttacttg ccggagtgta cattctagtg tggtgtatac tggtggctgt   1860

tgatgatgat tttttttttt ttacacaatt ctctgtagac taggagaaga atgcttgtgt   1920

ttttcggaag tgtgatgctt ctctttgact gccaaactct tttatggaat atatctttat   1980

attaatgctg ttttggtcat ttttgtttgg ggtcactatt gagatattgc taagcatctc   2040

agtggtaaac gcggctgcca gaggaaccaa gggatagggt atgtagacct tacagaagga   2100

tggatggtaa aggcagtcca tcatcagcac aatctgactt acatttcatt gagtaatttt   2160

tttttttttt aagattctgt atggcagcac tttcagttgc ccttgtgtgc cggccacagc   2220

cgcacaagtt ggcttgtggt ttatcccccg ctataagtga gagctggaga aacttcaact   2280

ccataggtct agaggaaaca ttgttttagg ttatttctgt ccacccctgt gcgatactat   2340

ttattgatcc aagcagaaga gcttggggac actgagtcga agtggggaca tgggattgaa   2400

gcctgggcac tgctgctgca tgagctgtgt gtcctgggtg tgccggcctt tctgtgaagg   2460

gggttggtgg cagtgcccac ctcactagat gcctctgacc cagcctcccc tgggggagtg   2520

ggtggccaca gaccctccct gccagagctc ctggaaggct cctgcaggcc tgacccatct   2580

attcctgtag acctggttta ggatgaagtc tcggtgcgat ttttgcagag ttgggtttat   2640

ctttcaacta tagacccttc tggctgttct cagccatatc atgtgactct gaatagttgg   2700

atgaggaatg gaaagaaagc aaggatgaga gccggtcacg tggcagtctc cgcccagcat   2760

cggctgtccg cacagaggca cagggcaggc ctcctgtgca ctccccacct agcactggcc   2820

tgtcctgaat ccccgccttc cctggttgga ggccagctgt ggcatttgca ccctcttctc   2880

acctcaccat gcacatgcta actttaaagc cttggggtct ttcctgtacc ccctcctcaa   2940

ccctggtcca ccccctctca ggatcttgtc aacgttattt ttcctgtccc gtcttcctat   3000

cgctggcctt cctttcccat cctaaaaact tgccgaggcc ctatggctcc ctccctttct   3060

ttcccaggca gcttcttatc tgggctgtct gtaccccttc ctttgcacca cccaccatgc   3120

cccacgtagc tgaaagctgc ttatcccaat tgtcaactct ggccttcttc agcctctgta   3180

gcaccagaca ctgcacctcc tgaatgtcct ctgcttctct gcttcagagg cccaggctcg   3240

ccagttctct gacctctccc atatgtctgc ttaggactct gctgcagctg tcctcaccag   3300

cctccgggga atcccactac ccacagggca gggctgtggg ctgggctgaa aaaccatctg   3360

catggtccac aagaagcctg gcactgggtt tccccatgaa taacaatgaa aattaatgga   3420

tgcac                                                               3425


<210>  7198
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  7198

Met Ser Pro Ser Ser Arg Lys Ala Ala Ser Arg Arg Trp Lys Ala Gly 
1               5                   10                  15


Ser Arg Gly Thr Phe Thr Leu Trp Leu Ala Ser Ser Ser Pro Ser Arg 
            20                  25                  30


Cys Cys Arg Tyr Leu Ala Ser Ser Trp Gln Gly Arg 
        35                  40


<210>  7199
<211>  5540
<212>  DNA
<213>  Homo sapiens

<400>  7199
tggagagtcc tccttgcctg cctcctggat ccctcgttcc caccctgctt tgccctgctc     60

cttaccagag ctcactaggg gatcaggtgg ggacatcgtg tgtgccaaag gctcagaccc    120

ctgtggtgtt ttcctgcagc tgaagagcaa gtgggatgag tccatcttca cgaaaggctg    180

catccaggcg ctggaaagct ggctcccgcg gaacatttac attgtggctg gcgtcttcat    240

cgccatctcg ctgttgcaga tatttggcat cttcctggca aggacgctga tctcagacat    300

cgaggcagtg aaggccggcc atcacttctg aggagcagag ttgagggagc cgagctgagc    360

cacgctggga ggccagagcc tttctctgcc atcagcccta cgtccagagg gagaggagcc    420

gacaccccca gagccagtgc cccatcttaa gcatcagcgt gacgtgacct ctctgtttct    480

gcttgctggt gctgaagacc aagggtcccc cttgttacct gcccaaactt gtgactgcat    540

ccctctggag tctacccaga gacagagaat gtgtctttat gtgggagtgg tgactctgaa    600

agacagagag ggctcctgtg gctgccagga gggcttgact cagaccccct gcagctcaag    660

catgtctgca ggacaccctg gtcccctctc cactggcatc cagacatctg ctttgggtca    720

tccacatctg tgggtgggcc gtgggtagag ggacccacag gcgtggacag ggcatctctc    780

tccatcaagc aaagcagcat gggggcctgc ccgtaacggg aggcggacgt ggccccgctg    840

ggcctctgag tgccagcgca gtctgctggg acatgcacat atcaggggtt gtttgcagga    900

tcctcagcca tgttcaagtg aagtaagcct gagccagtgc gtggactggt gccacgggag    960

tgccttgtcc actgtccccc tgtgtccacc agctattctc ctggcgccgg aactgcctct   1020

ggtcttgata gcattaagcc ctgatggcgc cggtggcgcg gtgggcatgg ttcttcactg   1080

agagccggct ctccttttct taaagtgtgt aaatagttta tttatagggg taagaatgtt   1140

ctcacaccat ttcacttcct cttcctctcc tccagcattc tcctctgagc agccttagat   1200

agtgtccatg gctggagccg accctttgag tccccttgag tgtcttaaga accagcccac   1260

aacagcctct ctttctcctc cacatactgc agcctccctc catgcatccc acatacaagc   1320

actcccccac tccccagcgt ggcctcactg tcttctggtc ttggtgctac tgaaattgtc   1380

acccagaatt tgaatcctga ccctccccac tgcaagccca gggagcccca gcccaagatg   1440

gccagcctga aactgttggc cagggctcct cttgtggcca tgtacccagg gctggctggc   1500

ctgccatttg cctctccccg gagacagccg ttcttctgca accacacccc gtgcctagcc   1560

acaaccccag gctgcagctg ctcagaagct ccaggcattt tgtttctggt gaccgcccct   1620

aatgggatat cggtgatcac tggtccaccc ttcctgtcag ggcttttctg gggctgctct   1680

tggaaatgaa gtcttaagta ctgaataact cccctgggga tagctggggc atttgtctag   1740

ctgggctact ttctaacact ttgccatagc tcagaccact tctcatcgtt cagggatgga   1800

ctgcaacctt aatttacttg ccggagtgta cattctagtg tggtgtatac tggtggctgt   1860

tgatgatgat tttttttttt ttacacaatt ctctgtagac taggagaaga atgcttgtgt   1920

ttttcggaag tgtgatgctt ctctttgact gccaaactct tttatggaat atatctttat   1980

attaatgctg ttttggtcat ttttgtttgg ggtcactatt gagatattgc taagcatctc   2040

agtggtaaac gcggctgcca gaggaaccaa gggatagggt atgtagacct tacagaagga   2100

tggatggtaa aggcagtcca tcatcagcac aatctgactt acatttcatt gagtaatttt   2160

tttttttttt aagattctgt atggcagcac tttcagttgc ccttgtgtgc cggccacagc   2220

cgcacaagtt ggcttgtggt ttatcccccg ctataagtga gagctggaga aacttcaact   2280

ccataggtct agaggaaaca ttgttttagg ttatttctgt ccacccctgt gcgatactat   2340

ttattgatcc aagcagaaga gcttggggac actgagtcga agtggggaca tgggattgaa   2400

gcctgggcac tgctgctgca tgagctgtgt gtcctgggtg tgccggcctt tctgtgaagg   2460

gggttggtgg cagtgcccac ctcactagat gcctctgacc cagcctcccc tgggggagtg   2520

ggtggccaca gaccctccct gccagagctc ctggaaggct cctgcaggcc tgacccatct   2580

attcctgtag acctggttta ggatgaagtc tcggtgcgat ttttgcagag ttgggtttat   2640

ctttcaacta tagacccttc tggctgttct cagccatatc atgtgactct gaatagttgg   2700

atgaggaatg gaaagaaagc aaggatgaga gccggtcacg tggcagtctc cgcccagcat   2760

cggctgtccg cacagaggca cagggcaggc ctcctgtgca ctccccacct agcactggcc   2820

tgtcctgaat ccccgccttc cctggttgga ggccagctgt ggcatttgca ccctcttctc   2880

acctcaccat gcacatgcta actttaaagc cttggggtct ttcctgtacc ccctcctcaa   2940

ccctggtcca ccccctctca ggatcttgtc aacgttattt ttcctgtccc gtcttcctat   3000

cgctggcctt cctttcccat cctaaaaact tgccgaggcc ctatggctcc ctccctttct   3060

ttcccaggca gcttcttatc tgggctgtct gtaccccttc ctttgcacca cccaccatgc   3120

cccacgtagc tgaaagctgc ttatcccaat tgtcaactct ggccttcttc agcctctgta   3180

gcaccagaca ctgcacctcc tgaatgtcct ctgcttctct gcttcagagg cccaggctcg   3240

ccagttctct gacctctccc atatgtctgc ttaggactct gctgcagctg tcctcaccag   3300

cctccgggga atcccactac ccacagggca gggctgtggg ctgggctgaa aaaccatctg   3360

catggtccac aagaagcctg gcactgggtt tccccatgaa taacaatgaa aattaatgga   3420

tgcacaacct tcctggaacg tggaatttct ctgggagatt ccatgcagag gccactgggg   3480

aggtggcagg catgcatgtg actgtaggtg gctgcagtgt tggaaggctc ccagcagagc   3540

agagagggtg tcagtctcat cagggaaccc acctgatggc ttctcagcca gcagtctcag   3600

aggaacatag acgactgctg agaaaggagg gaggcagcag tggtcccagc acctgaggca   3660

tcctgctgtc atgggaaggt ctccgcccaa atgtcagatg catcagcctg tcacccgctg   3720

gtccagagct ttcagctgta ctggtagggg gtgggtggtg gagtgctgaa tgaccttcac   3780

aggtgggcct ttccagctct agggtcttac gggtgtcggt ccacagaacc acggttttta   3840

ggttgtgtgt ccggggctat gggaacctgt cccccatgat ggatcttggt agagacactt   3900

ccctctgtca tcgtgcccag gaggatgctg caggtgacta cctgcagccc tgttctcatt   3960

catttggatg ccctccagaa atctggggag ccatacacct ttagagcctt ttttgctcct   4020

tatcaagttg gcaaggcttg gccaattcct gttcaaggct gcattaaagg catgttcacc   4080

atcctggcta atacggtgaa accccttctc tactaaaaat acaaaaaaat tagccgggct   4140

tggtggcggg tgcctgtagt cccagctact ccggaggctg aggcagggga atggtgtgaa   4200

cccaggaggc ggagcttgca gtgagccgag atcacaccac tgcactccag cctgggctca   4260

aaaaagaaaa aaaaaaaaaa aaaaaggccc gttcattctc aaatgctttt ggcgtctcca   4320

gggtgcctca ggaaaacatg aagtgggcat tgtagaactt ggggctactg tgtaactttg   4380

gaagaaaaag ttaagggtac ttttaagtgg atactgtttt gatgaaattg ccaacttcag   4440

ggagcccagc ttggagaagg aggacgtgag tattccttac aaggctccga aacaattctt   4500

tcttcactta gttttctttc tgtgctctgc atcttatatt ccagcagggt cttccaatgc   4560

atggtttaat aactactaga actggccagg tgcagtggct cacgcctgta atcccagaac   4620

tttgggaggc taagacaggc agatcacttg aggccaggag ttcgagacca gcctggacaa   4680

catggtgata cccagtttct actaaaaata caaaaattag tcgggcatgg tgatgtgcac   4740

ctgtagtccc agctgctcgg gaggctgagg caggagaatc gcttgaaccc gggagacaga   4800

ggttgcaacg agccaagatc gagccactgc gctccggcct gggtgacagg agactccatc   4860

tcaaaaaata aaattaaaaa aaaactacta caataaatta tcaccttgga ctgtataaaa   4920

caacttttaa actagtcttt ttaaaaagta cacttaaata aaaatctaaa cataagagaa   4980

tgtaaagtga aaagtgaaag tatgtcttct gttacgcaga ggtaactact attaggaatc   5040

cttcctgaaa atgtccatgc atctactcag gtcatcacac ccatggaatc attttacata   5100

ctattttatg agtgttactt aatatactga tccacagtgc gttttcacgg tcacgccatc   5160

agttgtagga gtgtgccaag aacagatggg ccttgccttt gtaccagagg agtccattta   5220

cagttgcagg taatagaaaa cccaattcag actggcctaa acaatgaggg gaggttttgg   5280

ctcttgaaac tggaaagtcc caaggtgggg tgagtttcag gtttgggttg atccaagtgg   5340

ctcagtgacg tcaacaggat cttgtttcca tttctctgcc ttccacagcc tccccttcat   5400

ctatggtgga gggaaggagt ctaccacaga caaaccccga gcctccccct gatgggtggt   5460

gtggtggtga agccagcaag ggaagggatc cccggacaca cccctcctca tgctttatcc   5520

cactgaaacc atgcggctgt                                               5540


<210>  7200
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  7200

Met Ser Pro Ser Ser Arg Lys Ala Ala Ser Arg Arg Trp Lys Ala Gly 
1               5                   10                  15


Ser Arg Gly Thr Phe Thr Leu Trp Leu Ala Ser Ser Ser Pro Ser Arg 
            20                  25                  30


Cys Cys Arg Tyr Leu Ala Ser Ser Trp Gln Gly Arg 
        35                  40


<210>  7201
<211>  2894
<212>  DNA
<213>  Homo sapiens

<400>  7201
cagatatttg gcatcttcct ggcaaggacg ctgatctcag acatcgaggc agtgaaggcc     60

ggccatcact tctgaggagc agagttgagg gagccgagct gagccacgct gggaggccag    120

agcctttctc tgccatcagc cctacgtcca gagggagagg agccgacacc cccagagcca    180

gtgccccatc ttaagcatca gcgtgacgtg acctctctgt ttctgcttgc tggtgctgaa    240

gaccaagggt cccccttgtt acctgcccaa acttgtgact gcatccctct ggagtctacc    300

cagagacaga gaatgtgtct ttatgtggga gtggtgactc tgaaagacag agagggctcc    360

tgtggctgcc aggagggctt gactcagacc ccctgcagct caagcatgtc tgcaggacac    420

cctggtcccc tctccactgg catccagaca tctgctttgg gtcatccaca tctgtgggtg    480

ggccgtgggt agagggaccc acaggcgtgg acagggcatc tctctccatc aagcaaagca    540

gcatgggggc ctgcccgtaa cgggaggcgg acgtggcccc gctgggcctc tgagtgccag    600

cgcagtctgc tgggacatgc acatatcagg ggttgtttgc aggatcctca gccatgttca    660

agtgaagtaa gcctgagcca gtgcgtggac tggtgccacg ggagtgcctt gtccactgtc    720

cccctgtgtc caccagctat tctcctggcg ccggaactgc ctctggtctt gatagcatta    780

agccctgatg gcgccggtgg cgcggtgggc atggttcttc actgagagcc ggctctcctt    840

ttcttaaagt gtgtaaatag tttatttata ggggtaagaa tgttctcaca ccatttcact    900

tcctcttcct ctcctccagc attctcctct gagcagcctt agatagtgtc catggctgga    960

gccgaccctt tgagtcccct tgagtgtctt aagaaccagc ccacaacagc ctctctttct   1020

cctccacata ctgcagcctc cctccatgca tcccacatac aagcactccc ccactcccca   1080

gcgtggcctc actgtcttct ggtcttggtg ctactgaaat tgtcacccag aatttgaatc   1140

ctgacctctt ggaaatgaag tcttaagtac tgaataactc ccctggggat agctggggca   1200

tttgtctagc tgggctactt tctaacactt tgccatagct cagaccactt ctcatcgttc   1260

agggatggac tgcaacctta atttacttgc cggagtgtac attctagtgt ggtgtatact   1320

ggtggctgtt gatgatgatt tttttttttt tacacaattc tctgtagact aggagaagaa   1380

tgcttgtgtt tttcggaagt gtgatgcttc tctttgactg ccaaactctt ttatggaata   1440

tatctttata ttaatgctgt tttggtcatt tttgtttggg gtcactattg agatattgct   1500

aagcatctca gtggtaaacg cggctgccag aggaaccaag ggatagggta tgtagacctt   1560

acagaaggat ggatggtaaa ggcagtccat catcagcaca atctgactta catttcattg   1620

agtaattttt ttttttttta agattctgta tggcagcact ttcagttgcc cttgtgtgcc   1680

ggccacagcc gcacaagttg gcttgtggtt tatcccccgc tataagtgag agctggagaa   1740

acttcaactc cataggtcta gaggaaacat tgttttaggt tatttctgtc cacccctgtg   1800

cgatactatt tattgatcca agcagaagag cttggggaca ctgagtcgaa gtggggacat   1860

gggattgaag cctgggcact gctgctgcat gagctgtgtg tcctgggtgt gccggccttt   1920

ctgtgaaggg ggttggtggc agtgcccacc tcactagatg cctctgaccc agcctcccct   1980

gggggagtgg gtggccacag accctccctg ccagagctcc tggaaggctc ctgcaggcct   2040

gacccatcta ttcctgtaga cctggtttag gatgaagtct cggtgcgatt tttgcagagt   2100

tgggtttatc tttcaactat agacccttct ggctgttctc agccatatca tgtgactctg   2160

aatagttgga tgaggaatgg aaagaaagca aggatgagag ccggtcacgt ggcagtctcc   2220

gcccagcatc ggctgtccgc acagaggcac agggcaggcc tcctgtgcac tccccaccta   2280

gcactggcct gtcctgaatc cccgccttcc ctggttggag gccagctgtg gcatttgcac   2340

cctcttctca cctcaccatg cacatgctaa ctttaaagcc ttggggtctt tcctgtaccc   2400

cctcctcaac cctggtccac cccctctcag gatcttgtca acgttatttt tcctgtcccg   2460

tcttcctatc gctggccttc ctttcccatc ctaaaaactt gccgaggccc tatggctccc   2520

tccctttctt tcccaggcag cttcttatct gggctgtctg taccccttcc tttgcaccac   2580

ccaccatgcc ccacgtagct gaaagctgct tatcccaatt gtcaactctg gccttcttca   2640

gcctctgtag caccagacac tgcacctcct gaatgtcctc tgcttctctg cttcagaggc   2700

ccaggctcgc cagttctctg acctctccca tatgtctgct taggactctg ctgcagctgt   2760

cctcaccagc ctccggggaa tcccactacc cacagggcag ggctgtgggc tgggctgaaa   2820

aaccatctgc atggtccaca agaagcctgg cactgggttt ccccatgaat aacaatgaaa   2880

attaatggat gcac                                                     2894


<210>  7202
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7202

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7203
<211>  5009
<212>  DNA
<213>  Homo sapiens

<400>  7203
cagatatttg gcatcttcct ggcaaggacg ctgatctcag acatcgaggc agtgaaggcc     60

ggccatcact tctgaggagc agagttgagg gagccgagct gagccacgct gggaggccag    120

agcctttctc tgccatcagc cctacgtcca gagggagagg agccgacacc cccagagcca    180

gtgccccatc ttaagcatca gcgtgacgtg acctctctgt ttctgcttgc tggtgctgaa    240

gaccaagggt cccccttgtt acctgcccaa acttgtgact gcatccctct ggagtctacc    300

cagagacaga gaatgtgtct ttatgtggga gtggtgactc tgaaagacag agagggctcc    360

tgtggctgcc aggagggctt gactcagacc ccctgcagct caagcatgtc tgcaggacac    420

cctggtcccc tctccactgg catccagaca tctgctttgg gtcatccaca tctgtgggtg    480

ggccgtgggt agagggaccc acaggcgtgg acagggcatc tctctccatc aagcaaagca    540

gcatgggggc ctgcccgtaa cgggaggcgg acgtggcccc gctgggcctc tgagtgccag    600

cgcagtctgc tgggacatgc acatatcagg ggttgtttgc aggatcctca gccatgttca    660

agtgaagtaa gcctgagcca gtgcgtggac tggtgccacg ggagtgcctt gtccactgtc    720

cccctgtgtc caccagctat tctcctggcg ccggaactgc ctctggtctt gatagcatta    780

agccctgatg gcgccggtgg cgcggtgggc atggttcttc actgagagcc ggctctcctt    840

ttcttaaagt gtgtaaatag tttatttata ggggtaagaa tgttctcaca ccatttcact    900

tcctcttcct ctcctccagc attctcctct gagcagcctt agatagtgtc catggctgga    960

gccgaccctt tgagtcccct tgagtgtctt aagaaccagc ccacaacagc ctctctttct   1020

cctccacata ctgcagcctc cctccatgca tcccacatac aagcactccc ccactcccca   1080

gcgtggcctc actgtcttct ggtcttggtg ctactgaaat tgtcacccag aatttgaatc   1140

ctgacctctt ggaaatgaag tcttaagtac tgaataactc ccctggggat agctggggca   1200

tttgtctagc tgggctactt tctaacactt tgccatagct cagaccactt ctcatcgttc   1260

agggatggac tgcaacctta atttacttgc cggagtgtac attctagtgt ggtgtatact   1320

ggtggctgtt gatgatgatt tttttttttt tacacaattc tctgtagact aggagaagaa   1380

tgcttgtgtt tttcggaagt gtgatgcttc tctttgactg ccaaactctt ttatggaata   1440

tatctttata ttaatgctgt tttggtcatt tttgtttggg gtcactattg agatattgct   1500

aagcatctca gtggtaaacg cggctgccag aggaaccaag ggatagggta tgtagacctt   1560

acagaaggat ggatggtaaa ggcagtccat catcagcaca atctgactta catttcattg   1620

agtaattttt ttttttttta agattctgta tggcagcact ttcagttgcc cttgtgtgcc   1680

ggccacagcc gcacaagttg gcttgtggtt tatcccccgc tataagtgag agctggagaa   1740

acttcaactc cataggtcta gaggaaacat tgttttaggt tatttctgtc cacccctgtg   1800

cgatactatt tattgatcca agcagaagag cttggggaca ctgagtcgaa gtggggacat   1860

gggattgaag cctgggcact gctgctgcat gagctgtgtg tcctgggtgt gccggccttt   1920

ctgtgaaggg ggttggtggc agtgcccacc tcactagatg cctctgaccc agcctcccct   1980

gggggagtgg gtggccacag accctccctg ccagagctcc tggaaggctc ctgcaggcct   2040

gacccatcta ttcctgtaga cctggtttag gatgaagtct cggtgcgatt tttgcagagt   2100

tgggtttatc tttcaactat agacccttct ggctgttctc agccatatca tgtgactctg   2160

aatagttgga tgaggaatgg aaagaaagca aggatgagag ccggtcacgt ggcagtctcc   2220

gcccagcatc ggctgtccgc acagaggcac agggcaggcc tcctgtgcac tccccaccta   2280

gcactggcct gtcctgaatc cccgccttcc ctggttggag gccagctgtg gcatttgcac   2340

cctcttctca cctcaccatg cacatgctaa ctttaaagcc ttggggtctt tcctgtaccc   2400

cctcctcaac cctggtccac cccctctcag gatcttgtca acgttatttt tcctgtcccg   2460

tcttcctatc gctggccttc ctttcccatc ctaaaaactt gccgaggccc tatggctccc   2520

tccctttctt tcccaggcag cttcttatct gggctgtctg taccccttcc tttgcaccac   2580

ccaccatgcc ccacgtagct gaaagctgct tatcccaatt gtcaactctg gccttcttca   2640

gcctctgtag caccagacac tgcacctcct gaatgtcctc tgcttctctg cttcagaggc   2700

ccaggctcgc cagttctctg acctctccca tatgtctgct taggactctg ctgcagctgt   2760

cctcaccagc ctccggggaa tcccactacc cacagggcag ggctgtgggc tgggctgaaa   2820

aaccatctgc atggtccaca agaagcctgg cactgggttt ccccatgaat aacaatgaaa   2880

attaatggat gcacaacctt cctggaacgt ggaatttctc tgggagattc catgcagagg   2940

ccactgggga ggtggcaggc atgcatgtga ctgtaggtgg ctgcagtgtt ggaaggctcc   3000

cagcagagca gagagggtgt cagtctcatc agggaaccca cctgatggct tctcagccag   3060

cagtctcaga ggaacataga cgactgctga gaaaggaggg aggcagcagt ggtcccagca   3120

cctgaggcat cctgctgtca tgggaaggtc tccgcccaaa tgtcagatgc atcagcctgt   3180

cacccgctgg tccagagctt tcagctgtac tggtaggggg tgggtggtgg agtgctgaat   3240

gaccttcaca ggtgggcctt tccagctcta gggtcttacg ggtgtcggtc cacagaacca   3300

cggtttttag gttgtgtgtc cggggctatg ggaacctgtc ccccatgatg gatcttggta   3360

gagacacttc cctctgtcat cgtgcccagg aggatgctgc aggtgactac ctgcagccct   3420

gttctcattc atttggatgc cctccagaaa tctggggagc catacacctt tagagccttt   3480

tttgctcctt atcaagttgg caaggcttgg ccaattcctg ttcaaggctg cattaaaggc   3540

atgttcacca tcctggctaa tacggtgaaa ccccttctct actaaaaata caaaaaaatt   3600

agccgggctt ggtggcgggt gcctgtagtc ccagctactc cggaggctga ggcaggggaa   3660

tggtgtgaac ccaggaggcg gagcttgcag tgagccgaga tcacaccact gcactccagc   3720

ctgggctcaa aaaagaaaaa aaaaaaaaaa aaaaggcccg ttcattctca aatgcttttg   3780

gcgtctccag ggtgcctcag gaaaacatga agtgggcatt gtagaacttg gggctactgt   3840

gtaactttgg aagaaaaagt taagggtact tttaagtgga tactgttttg atgaaattgc   3900

caacttcagg gagcccagct tggagaagga ggacgtgagt attccttaca aggctccgaa   3960

acaattcttt cttcacttag ttttctttct gtgctctgca tcttatattc cagcagggtc   4020

ttccaatgca tggtttaata actactagaa ctggccaggt gcagtggctc acgcctgtaa   4080

tcccagaact ttgggaggct aagacaggca gatcacttga ggccaggagt tcgagaccag   4140

cctggacaac atggtgatac ccagtttcta ctaaaaatac aaaaattagt cgggcatggt   4200

gatgtgcacc tgtagtccca gctgctcggg aggctgaggc aggagaatcg cttgaacccg   4260

ggagacagag gttgcaacga gccaagatcg agccactgcg ctccggcctg ggtgacagga   4320

gactccatct caaaaaataa aattaaaaaa aaactactac aataaattat caccttggac   4380

tgtataaaac aacttttaaa ctagtctttt taaaaagtac acttaaataa aaatctaaac   4440

ataagagaat gtaaagtgaa aagtgaaagt atgtcttctg ttacgcagag gtaactacta   4500

ttaggaatcc ttcctgaaaa tgtccatgca tctactcagg tcatcacacc catggaatca   4560

ttttacatac tattttatga gtgttactta atatactgat ccacagtgcg ttttcacggt   4620

cacgccatca gttgtaggag tgtgccaaga acagatgggc cttgcctttg taccagagga   4680

gtccatttac agttgcaggt aatagaaaac ccaattcaga ctggcctaaa caatgagggg   4740

aggttttggc tcttgaaact ggaaagtccc aaggtggggt gagtttcagg tttgggttga   4800

tccaagtggc tcagtgacgt caacaggatc ttgtttccat ttctctgcct tccacagcct   4860

ccccttcatc tatggtggag ggaaggagtc taccacagac aaaccccgag cctccccctg   4920

atgggtggtg tggtggtgaa gccagcaagg gaagggatcc ccggacacac ccctcctcat   4980

gctttatccc actgaaacca tgcggctgt                                     5009


<210>  7204
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  7204

Met His Met Leu Thr Leu Lys Pro Trp Gly Leu Ser Cys Thr Pro Ser 
1               5                   10                  15


Ser Thr Leu Val His Pro Leu Ser Gly Ser Cys Gln Arg Tyr Phe Ser 
            20                  25                  30


Cys Pro Val Phe Leu Ser Leu Ala Phe Leu Ser His Pro Lys Asn Leu 
        35                  40                  45


Pro Arg Pro Tyr Gly Ser Leu Pro Phe Phe Pro Arg Gln Leu Leu Ile 
    50                  55                  60


Trp Ala Val Cys Thr Pro Ser Phe Ala Pro Pro Thr Met Pro His Val 
65                  70                  75                  80


Ala Glu Ser Cys Leu Ser Gln Leu Ser Thr Leu Ala Phe Phe Ser Leu 
                85                  90                  95


Cys Ser Thr Arg His Cys Thr Ser 
            100


<210>  7205
<211>  2198
<212>  DNA
<213>  Homo sapiens

<400>  7205
gggcctctga gtgccagcgc agtctgctgg gacatgcaca tatcaggggt tgtttgcagg     60

atcctcagcc atgttcaagt gaagtaagcc tgagccagtg cgtggactgg tgccacggga    120

gtgccttgtc cactgtcccc ctgtgtccac cagctattct cctggcgccg gaactgcctc    180

tggtcttgat agcattaagc cctgatggcg ccggtggcgc ggtgggcatg gttcttcact    240

gagagccggc tctccttttc ttaaagtgtg taaatagttt atttataggg gtaagaatgt    300

tctcacacca tttcacttcc tcttcctctc ctccagcatt ctcctctgag cagccttaga    360

tagtgtccat ggctggagcc gaccctttga gtccccttga gtgtcttaag aaccagccca    420

caacagcctc tctttctcct ccacatactg cagcctccct ccatgcatcc cacatacaag    480

cactccccca ctccccagcg tggcctcact gtcttctggt cttggtgcta ctgaaattgt    540

cacccagaat ttgaatcctg accctcccca ctgcaagccc agggagcccc agcccaagat    600

ggccagcctg aaactgttgg ccagggctcc tcttgtggcc atgtacccag ggctggctgg    660

cctgccattt gcctctcccc ggagacagcc gttcttctgc aaccacaccc cgtgcctagc    720

cacaacccca ggctgcagct gctcagaagc tccaggcatt ttgtttctgg tgaccgcccc    780

taatgggata tcggtgatca ctggtccacc cttcctgtca gggcttttct ggggctgctc    840

ttggaaatga agtcttaagt actgaataac tcccctgggg atagctgggg catttgtcta    900

gctgggctac tttctaacac tttgccatag ctcagaccac ttctcatcgt tcattctcaa    960

atgcttttgg cgtctccagg gtgcctcagg aaaacatgaa gtgggcattg tagaacttgg   1020

ggctactgtg taactttgga agaaaaagtt aagggtactt ttaagtggat actgttttga   1080

tgaaattgcc aacttcaggg agcccagctt ggagaaggag gacgtgagta ttccttacaa   1140

ggctccgaaa caattctttc ttcacttagt tttctttctg tgctctgcat cttatattcc   1200

agcagggtct tccaatgcat ggtttaataa ctactagaac tggccaggtg cagtggctca   1260

cgcctgtaat cccagaactt tgggaggcta agacaggcag atcacttgag gccaggagtt   1320

cgagaccagc ctggacaaca tggtgatacc cagtttctac taaaaataca aaaattagtc   1380

gggcatggtg atgtgcacct gtagtcccag ctgctcggga ggctgaggca ggagaatcgc   1440

ttgaacccgg gagacagagg ttgcaacgag ccaagatcga gccactgcgc tccggcctgg   1500

gtgacaggag actccatctc aaaaaataaa attaaaaaaa aactactaca ataaattatc   1560

accttggact gtataaaaca acttttaaac tagtcttttt aaaaagtaca cttaaataaa   1620

aatctaaaca taagagaatg taaagtgaaa agtgaaagta tgtcttctgt tacgcagagg   1680

taactactat taggaatcct tcctgaaaat gtccatgcat ctactcaggt catcacaccc   1740

atggaatcat tttacatact attttatgag tgttacttaa tatactgatc cacagtgcgt   1800

tttcacggtc acgccatcag ttgtaggagt gtgccaagaa cagatgggcc ttgcctttgt   1860

accagaggag tccatttaca gttgcaggta atagaaaacc caattcagac tggcctaaac   1920

aatgagggga ggttttggct cttgaaactg gaaagtccca aggtggggtg agtttcaggt   1980

ttgggttgat ccaagtggct cagtgacgtc aacaggatct tgtttccatt tctctgcctt   2040

ccacagcctc cccttcatct atggtggagg gaaggagtct accacagaca aaccccgagc   2100

ctccccctga tgggtggtgt ggtggtgaag ccagcaaggg aagggatccc cggacacacc   2160

cctcctcatg ctttatccca ctgaaaccat gcggctgt                           2198


<210>  7206
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  7206

Met Ala Ser Leu Lys Leu Leu Ala Arg Ala Pro Leu Val Ala Met Tyr 
1               5                   10                  15


Pro Gly Leu Ala Gly Leu Pro Phe Ala Ser Pro Arg Arg Gln Pro Phe 
            20                  25                  30


Phe Cys Asn His Thr Pro Cys Leu Ala Thr Thr Pro Gly Cys Ser Cys 
        35                  40                  45


Ser Glu Ala Pro Gly Ile Leu Phe Leu Val Thr Ala Pro Asn Gly Ile 
    50                  55                  60


Ser Val Ile Thr Gly Pro Pro Phe Leu Ser Gly Leu Phe Trp Gly Cys 
65                  70                  75                  80


Ser Trp Lys 



<210>  7207
<211>  1605
<212>  DNA
<213>  Homo sapiens

<400>  7207
cttagatagt gtccatggct ggagccgacc ctttgagtcc ccttgagtgt cttaagaacc     60

agcccacaac agcctctctt tctcctccac atactgcagc ctccctccat gcatcccaca    120

tacaagcact cccccactcc ccagcgtggc ctcactgtct tctggtcttg gtgctactga    180

aattgtcacc cagaatttga atcctgaccc tccccactgc aagcccaggg agccccagcc    240

caagatggcc agcctgaaac tgttggccag ggctcctctt gtggccatgt acccagggct    300

ggctggcctg ccatttgcct ctccccggag acagccgttc ttctgcaacc acaccccgtg    360

cctagccaca accccaggct gcagctgctc agaagctcca ggcattttgt ttctggtgac    420

cgcccctaat gggatatcgg tgatcactgg tccacccttc ctgtcagggc ttttctgggg    480

ctgctcttgg aaatgaagtc ttaagtactg aataactccc ctggggatag ctggggcatt    540

tgtctagctg ggctactttc taacactttg ccatagctca gaccacttct catcgttcag    600

ggatggactg caaccttaat ttacttgccg gagtgtacat tctagtgtgg tgtatactgg    660

tggctgttga tgatgatttt ttttttttta cacaattctc tgtagactag gagaagaatg    720

cttgtgtttt tcggaagtgt gatgcttctc tttgactgcc aaactctttt atggaatata    780

tctttatatt aatgctgttt tggtcatttt tgtttggggt cactattgag atattgctaa    840

gcatctcagt ggtaaacgcg gctgccagag gaaccaaggg atagggtatg tagaccttac    900

agaaggatgg atggtaaagg cagtccatca tcagcacaat ctgacttaca tttcacaata    960

aattatcacc ttggactgta taaaacaact tttaaactag tctttttaaa aagtacactt   1020

aaataaaaat ctaaacataa gagaatgtaa agtgaaaagt gaaagtatgt cttctgttac   1080

gcagaggtaa ctactattag gaatccttcc tgaaaatgtc catgcatcta ctcaggtcat   1140

cacacccatg gaatcatttt acatactatt ttatgagtgt tacttaatat actgatccac   1200

agtgcgtttt cacggtcacg ccatcagttg taggagtgtg ccaagaacag atgggccttg   1260

cctttgtacc agaggagtcc atttacagtt gcaggtaata gaaaacccaa ttcagactgg   1320

cctaaacaat gaggggaggt tttggctctt gaaactggaa agtcccaagg tggggtgagt   1380

ttcaggtttg ggttgatcca agtggctcag tgacgtcaac aggatcttgt ttccatttct   1440

ctgccttcca cagcctcccc ttcatctatg gtggagggaa ggagtctacc acagacaaac   1500

cccgagcctc cccctgatgg gtggtgtggt ggtgaagcca gcaagggaag ggatccccgg   1560

acacacccct cctcatgctt tatcccactg aaaccatgcg gctgt                   1605


<210>  7208
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  7208

Met Asp Gly Lys Gly Ser Pro Ser Ser Ala Gln Ser Asp Leu His Phe 
1               5                   10                  15


Thr Ile Asn Tyr His Leu Gly Leu Tyr Lys Thr Thr Phe Lys Leu Val 
            20                  25                  30


Phe Leu Lys Ser Thr Leu Lys 
        35


<210>  7209
<211>  3350
<212>  DNA
<213>  Homo sapiens

<400>  7209
gaaggatgga tggtaaaggc agtccatcat cagcacaatc tgacttacat ttcattgagt     60

aatttttttt ttttttaaga ttctgtatgg cagcactttc agttgccctt gtgtgccggc    120

cacagccgca caagttggct tgtggtttat cccccgctat aagtgagagc tggagaaact    180

tcaactccat aggtctagag gaaacattgt tttaggttat ttctgtccac ccctgtgcga    240

tactatttat tgatccaagc agaagagctt ggggacactg agtcgaagtg gggacatggg    300

attgaagcct gggcactgct gctgcatgag ctgtgtgtcc tgggtgtgcc ggcctttctg    360

tgaagggggt tggtggcagt gcccacctca ctagatgcct ctgacccagc ctcccctggg    420

ggagtgggtg gccacagacc ctccctgcca gagctcctgg aaggctcctg caggcctgac    480

ccatctattc ctgtagacct ggtttaggat gaagtctcgg tgcgattttt gcagagttgg    540

gtttatcttt caactataga cccttctggc tgttctcagc catatcatgt gactctgaat    600

agttggatga ggaatggaaa gaaagcaagg atgagagccg gtcacgtggc agtctccgcc    660

cagcatcggc tgtccgcaca gaggcacagg gcaggcctcc tgtgcactcc ccacctagca    720

ctggcctgtc ctgaatcccc gccttccctg gttggaggcc agctgtggca tttgcaccct    780

cttctcacct caccatgcac atgctaactt taaagccttg gggtctttcc tgtaccccct    840

cctcaaccct ggtccacccc ctctcaggat cttgtcaacg ttatttttcc tgtcccgtct    900

tcctatcgct ggccttcctt tcccatccta aaaacttgcc gaggccctat ggctccctcc    960

ctttctttcc caggcagctt cttatctggg ctgtctgtac cccttccttt gcaccaccca   1020

ccatgcccca cgtagctgaa agctgcttat cccaattgtc aactctggcc ttcttcagcc   1080

tctgtagcac cagacactgc acctcctgaa tgtcctctgc ttctctgctt cagaggccca   1140

ggctcgccag ttctctgacc tctcccatat gtctgcttag gactctgctg cagctgtcct   1200

caccagcctc cggggaatcc cactacccac agggcagggc tgtgggctgg gctgaaaaac   1260

catctgcatg gtccacaaga agcctggcac tgggtttccc catgaataac aatgaaagtg   1320

gctgcagtgt tggaaggctc ccagcagagc agagagggtg tcagtctcat cagggaaccc   1380

acctgatggc ttctcagcca gcagtctcag aggaacatag acgactgctg agaaaggagg   1440

gaggcagcag tggtcccagc acctgaggca tcctgctgtc atgggaaggt ctccgcccaa   1500

atgtcagatg catcagcctg tcacccgctg gtccagagct ttcagctgta ctggtagggg   1560

gtgggtggtg gagtgctgaa tgaccttcac aggtgggcct ttccagctct agggtcttac   1620

gggtgtcggt ccacagaacc acggttttta ggttgtgtgt ccggggctat gggaacctgt   1680

cccccatgat ggatcttggt agagacactt ccctctgtca tcgtgcccag gaggatgctg   1740

caggtgacta cctgcagccc tgttctcatt catttggatg ccctccagaa atctggggag   1800

ccatacacct ttagagcctt ttttgctcct tatcaagttg gcaaggcttg gccaattcct   1860

gttcaaggct gcattaaagg catgttcacc atcctggcta atacggtgaa accccttctc   1920

tactaaaaat acaaaaaaat tagccgggct tggtggcggg tgcctgtagt cccagctact   1980

ccggaggctg aggcagggga atggtgtgaa cccaggaggc ggagcttgca gtgagccgag   2040

atcacaccac tgcactccag cctgggctca aaaaagaaaa aaaaaaaaaa aaaaaggccc   2100

gttcattctc aaatgctttt ggcgtctcca gggtgcctca ggaaaacatg aagtgggcat   2160

tgtagaactt ggggctactg tgtaactttg gaagaaaaag ttaagggtac ttttaagtgg   2220

atactgtttt gatgaaattg ccaacttcag ggagcccagc ttggagaagg aggacgtgag   2280

tattccttac aaggctccga aacaattctt tcttcactta gttttctttc tgtgctctgc   2340

atcttatatt ccagcagggt cttccaatgc atggtttaat aactactaga actggccagg   2400

tgcagtggct cacgcctgta atcccagaac tttgggaggc taagacaggc agatcacttg   2460

aggccaggag ttcgagacca gcctggacaa catggtgata cccagtttct actaaaaata   2520

caaaaattag tcgggcatgg tgatgtgcac ctgtagtccc agctgctcgg gaggctgagg   2580

caggagaatc gcttgaaccc gggagacaga ggttgcaacg agccaagatc gagccactgc   2640

gctccggcct gggtgacagg agactccatc tcaaaaaata aaattaaaaa aaaactacta   2700

caataaatta tcaccttgga ctgtataaaa caacttttaa actagtcttt ttaaaaagta   2760

cacttaaata aaaatctaaa cataagagaa tgtaaagtga aaagtgaaag tatgtcttct   2820

gttacgcaga ggtaactact attaggaatc cttcctgaaa atgtccatgc atctactcag   2880

gtcatcacac ccatggaatc attttacata ctattttatg agtgttactt aatatactga   2940

tccacagtgc gttttcacgg tcacgccatc agttgtagga gtgtgccaag aacagatggg   3000

ccttgccttt gtaccagagg agtccattta cagttgcagg taatagaaaa cccaattcag   3060

actggcctaa acaatgaggg gaggttttgg ctcttgaaac tggaaagtcc caaggtgggg   3120

tgagtttcag gtttgggttg atccaagtgg ctcagtgacg tcaacaggat cttgtttcca   3180

tttctctgcc ttccacagcc tccccttcat ctatggtgga gggaaggagt ctaccacaga   3240

caaaccccga gcctccccct gatgggtggt gtggtggtga agccagcaag ggaagggatc   3300

cccggacaca cccctcctca tgctttatcc cactgaaacc atgcggctgt              3350


<210>  7210
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  7210

Met Ser Ser Ala Ser Leu Leu Gln Arg Pro Arg Leu Ala Ser Ser Leu 
1               5                   10                  15


Thr Ser Pro Ile Cys Leu Leu Arg Thr Leu Leu Gln Leu Ser Ser Pro 
            20                  25                  30


Ala Ser Gly Glu Ser His Tyr Pro Gln Gly Arg Ala Val Gly Trp Ala 
        35                  40                  45


Glu Lys Pro Ser Ala Trp Ser Thr Arg Ser Leu Ala Leu Gly Phe Pro 
    50                  55                  60


Met Asn Asn Asn Glu Ser Gly Cys Ser Val Gly Arg Leu Pro Ala Glu 
65                  70                  75                  80


Gln Arg Gly Cys Gln Ser His Gln Gly Thr His Leu Met Ala Ser Gln 
                85                  90                  95


Pro Ala Val Ser Glu Glu His Arg Arg Leu Leu Arg Lys Glu Gly Gly 
            100                 105                 110


Ser Ser Gly Pro Ser Thr 
        115


<210>  7211
<211>  596
<212>  DNA
<213>  Homo sapiens

<400>  7211
gaccccagga gcaggggtcg cgccgaagag cagagtccgc ggctggaaac caggcagggg     60

agccacggag tagtcacaca ggttttctgc cgcctttcaa ctggtcttat tttgctttca    120

tttttcacca gcccatgtgg ggtgtttaat gttgcacgcg aacgcagttt cttccgggcc    180

cggaaggccc acgcacgcaa caatgttgtg caagtgactg gaaaccacct gagtgtccct    240

ccatgggggt gggttgccca gcatggacct ctactcctgt cacaatgaag tcgactgttt    300

cgtcgaggga agtggccacc gttgataaaa tgaaaagacg ccatgcagaa tactgtgcac    360

aggaggaaag gtctgcgtgc cctaagagag agctgctggc gtgcagagag aagcagagat    420

gccgacgacg gggaggaaac acactggcgg tggtgaggct ccttccagca gccacagccc    480

tggttcctct cagtctgtga ccctcccaca tccttcccat ctatgagagc ctgtaaactc    540

cttttgctta accttgtttt agttaaggtt ttaaacagtt gccaccagtg tgccct        596


<210>  7212
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  7212

Met Gly Val Gly Cys Pro Ala Trp Thr Ser Thr Pro Val Thr Met Lys 
1               5                   10                  15


Ser Thr Val Ser Ser Arg Glu Val Ala Thr Val Asp Lys Met Lys Arg 
            20                  25                  30


Arg His Ala Glu Tyr Cys Ala Gln Glu Glu Arg Ser Ala Cys Pro Lys 
        35                  40                  45


Arg Glu Leu Leu Ala Cys Arg Glu Lys Gln Arg Cys Arg Arg Arg Gly 
    50                  55                  60


Gly Asn Thr Leu Ala Val Val Arg Leu Leu Pro Ala Ala Thr Ala Leu 
65                  70                  75                  80


Val Pro Leu Ser Leu 
                85


<210>  7213
<211>  346
<212>  DNA
<213>  Homo sapiens

<400>  7213
agcctccagc tcagccagga aatgcccagt cccagccctg cctgggctgg taggtgtcga     60

gtgatctgtt agtggaaggt aacaatgaca ccagctatat caatgacact gccccggcca    120

gctgggaact gatctctcct ctgcagataa gaggaggaga aggaggcaga cttgcctact    180

aaattccatg tcttttcagc caatttcaaa cacagaccag aggaggagag ggagaggagg    240

gagagggaga ggaggagcct ttcccagggt aatccatttt taaaattctg tatgtccgat    300

tacttttgtg gagacaaagg gaaaagtaca gaagatcaca cgccta                   346


<210>  7214
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  7214

Met Ser Phe Gln Pro Ile Ser Asn Thr Asp Gln Arg Arg Arg Gly Arg 
1               5                   10                  15


Gly Gly Arg Gly Arg Gly Gly Ala Phe Pro Arg Val Ile His Phe 
            20                  25                  30


<210>  7215
<211>  3983
<212>  DNA
<213>  Homo sapiens

<400>  7215
actaacagat cactcgacac ctaccagccc aggcagggct gggactgggc atttcctggc     60

tgagctggag gcttgggccc ttcccattgt ctcagaaccc caggtgatgc caagacatgg    120

gctctcctgg gatgccgtgc ttggtgaccc aggagaagga ctagattgct cctggtggtt    180

gctccccctt gcagagtccc acctgcccct ttgggtcctg ttgcctggcc tcttttgctg    240

tcctgggtag aggagatgag ttcgtcgctg gctgcaagct gaggccaact gacaatgctg    300

cacagagaag gggcaccgag agtggccccg gattgagcag tccgtagtgc agagcagccc    360

ctcgggcgtt ctgcctggcc ctgcttcccc tgctggctgc ccttctggtg cgtgcatccc    420

aggtggcatc atgctgcagc agatcctgca cgacatgtac atcgaccccg agctccttgc    480

cgagctcagc gatgtgcaga agcacatcct cttctacaaa atgcgggagg agcagctgag    540

gcgctggaag gagcgggaga cttgggaggc cctggcccag gacgagggtc tcaggcctcc    600

aaagaccaag cgagcagcga gtgacaagca catccaatgg ctcctagggg cagatggcga    660

ggtctgggtc tggatcatgg gagaaggccc tggtgacaag ccctacgaag agatctctga    720

ggagctgatt gcagagaggg cgcggctgca ggcacagagg gaagctgagg agctctggag    780

acagaaggag gcagagatca ccaagaagtt ccgggatgct ctggccaatg agaaagcccg    840

gatcttggcg gagaagtgga aagtggagat ggaagaccgc aaggctgcca aagtcctgga    900

ggaacgcatc cacgaggaat tcaagaggaa agaggaagag gagaggaagc gaggagaaga    960

gcagattcgc ctccaggaag agcagagggc gaaggagctc tactggaccc tgaagcaggc   1020

tcagctgcat tgccaagcca gtgagaaaga ggagcgagag tgggaagaac agttgcgccg   1080

gtccaaggcg gctgatgagg agaggagccg ccgagcccag cgcgcccggg acgagtaccg   1140

acaccactcg ctccgtgcta tccagaaggg cacggtcgct ggcctcagct ccatgttccg   1200

ggagcttggc cagagccatg agcaggaggc aagactctac caccacctcc ccgacccggg   1260

tctgccgcag ccccttgccc tgccggtcag gacctgggag cgcccgctgc gcccagtctc   1320

cagagatgtc atcgtccgct ggtttaagga ggagcagctg cctcgccgag ctggcttcga   1380

gaggaacacc aagttcatcg ccccctggtt ccatggagga aattatcact gtttcaggag   1440

gagagttact tcaggaaccc tgcggacaga gggacagccc accagactac catctgttgt   1500

ttgaataatt tttttcctta tcaattggat tcattttggt atcctgtttt tgaactcagc   1560

ttaagaactt ctcatctcaa atcctatggc cttctggaag atccaccact atccaaagga   1620

aaaagtagat taatatgcct caagggatat gacatctatg gcatagggct actggtctca   1680

tcccagcgat cgggacagaa attgctaata gctcatgcaa ctctttcatg aagagcttag   1740

ctatgacctt agaagacaaa gcctgtttgt catggctgcc gtaaaccgag ctcttacagt   1800

gcgtggacca tgttttaata atccaaaata attccagtgc cgaaccctga atttaacata   1860

tggtagacat tcagtaaatg tttgttgaat gaatgcatgt cttctaaaag ttttccaaca   1920

caaattagca gtggtttctt gtaaattatt tcctactcgc cactctataa aatcatggca   1980

ataatagaag attatgaagg atttctatgg aggacataaa tgctgcatct ttcataatct   2040

ccattatcac cctcattgat attatcattg gaattatcta aggtgagccc cagtttccag   2100

ggcagctgat tgacaccgtc ctgccttcct tatttaacct cttcttttgc cactcgcctc   2160

tatctttgaa tcatattttg gccttggttt tgcaatggtt ttatgtcatc ctacagatgt   2220

cttcaagacc tggggtgagt tatcaatgca agaatggttc ttagaaatct gatgaggcct   2280

ctgctctctg ggatgtggcc ctctctatgc aggttactcc aatgattagc tctgtcctca   2340

ttgtcctttt aattcccttg tcaacttaat ctcagtatgt tgcttatatt aacaagaaga   2400

ctcacgcaat aactcctcga taactctcag tgatggtatc tgttggtgca tacttgtgtt   2460

ccacagttat ggccatatac acagaggtag tatatgatga agagaagatt acagtcttta   2520

cagtcaagaa gacttgggtt catatcctaa ccctggaact tactagcatt ataatgcttg   2580

cagcattgtg tttggtgaga ggaaaagaat gaatggattc taggaatgtt agggaacgat   2640

ttactttacc cgatggctgt atcaaacatc tatgccccac ttcttctctt gcctcaccta   2700

ttccttagat tcttggtcac ttctctacca caagccacca gcactataac cagttttgcg   2760

tgggttctgc tcttcctccc tatgttgatc agtgtcatgt gagcataagc caatggtagc   2820

ttgccacatg ccccatctcc cattgctgca gaggcataag acagaagaga tgggaagtga   2880

atgcccgatg tggtgaatct gggatgaatg ggagtcatag gctggtagat cgctttttcc   2940

tccttcttcc tcctggagga actattctga gagtcatctg tttgtatggt cttgtagaag   3000

acagtcctgt aagatcgagc aaccagtcat gatgaaacca agtggtggcc ggatcagtat   3060

gacaccctgc tgcccccgtt tttaattctt ctctgccttg ccctgctctc tcctgttgct   3120

ctgggattgc acttctgaat gaagtagcag ctcataagct tttgccacag gctctgtctt   3180

ttggggaatc caggataaga acccattata cagaagtgtt caataatatc aattttgcaa   3240

ctcactcagc tccatggctt cccccggtct acctgtctca ctacatgcat aaagtgaaat   3300

gatggaagga atctgctttc tgaactctaa tgtgccttca ttgattatca ttaaaattat   3360

cattaaaatt gccttatttc tatggactca gaggaatgat gttttagttt tggctctctg   3420

atttaccaac tatgtgactt tgtccaagtc atttaacttc agtaaacctc ggtatgactg   3480

aaaagggagt tttctgtatg gccgtcacta ggtttttttg tgggttagtt aaatgataaa   3540

catgaaagct ctgtccaaat gaaaaaggta tttctaacaa caaccacaat aacaataaca   3600

acttagtgct tagcccatga tgtatcaggg gatatgatgt gatgattttc aaggtgttgg   3660

aggcaacttc tgttccaaga actcccagca gctttgaaag cagactgaga tgagttgaga   3720

ccctgaatcc ctgggctgtt gttcctgtca cccctaatta atatgtgaga gacaacagct   3780

gggttttcca tccctaacac atttatttca ttttatttgg ggcctgcaat ttctgcatgt   3840

ctcatatatt ttaggtttta cctttttacc tggctttaaa ataaatccct tgtaagttgt   3900

cctgcaaatg aaattactgt ctggaaaact gcaatttcat cttgagagtt ttattatgct   3960

aataaatgtc aggattctca tat                                           3983


<210>  7216
<211>  357
<212>  PRT
<213>  Homo sapiens

<400>  7216

Met Leu Gln Gln Ile Leu His Asp Met Tyr Ile Asp Pro Glu Leu Leu 
1               5                   10                  15


Ala Glu Leu Ser Asp Val Gln Lys His Ile Leu Phe Tyr Lys Met Arg 
            20                  25                  30


Glu Glu Gln Leu Arg Arg Trp Lys Glu Arg Glu Thr Trp Glu Ala Leu 
        35                  40                  45


Ala Gln Asp Glu Gly Leu Arg Pro Pro Lys Thr Lys Arg Ala Ala Ser 
    50                  55                  60


Asp Lys His Ile Gln Trp Leu Leu Gly Ala Asp Gly Glu Val Trp Val 
65                  70                  75                  80


Trp Ile Met Gly Glu Gly Pro Gly Asp Lys Pro Tyr Glu Glu Ile Ser 
                85                  90                  95


Glu Glu Leu Ile Ala Glu Arg Ala Arg Leu Gln Ala Gln Arg Glu Ala 
            100                 105                 110


Glu Glu Leu Trp Arg Gln Lys Glu Ala Glu Ile Thr Lys Lys Phe Arg 
        115                 120                 125


Asp Ala Leu Ala Asn Glu Lys Ala Arg Ile Leu Ala Glu Lys Trp Lys 
    130                 135                 140


Val Glu Met Glu Asp Arg Lys Ala Ala Lys Val Leu Glu Glu Arg Ile 
145                 150                 155                 160


His Glu Glu Phe Lys Arg Lys Glu Glu Glu Glu Arg Lys Arg Gly Glu 
                165                 170                 175


Glu Gln Ile Arg Leu Gln Glu Glu Gln Arg Ala Lys Glu Leu Tyr Trp 
            180                 185                 190


Thr Leu Lys Gln Ala Gln Leu His Cys Gln Ala Ser Glu Lys Glu Glu 
        195                 200                 205


Arg Glu Trp Glu Glu Gln Leu Arg Arg Ser Lys Ala Ala Asp Glu Glu 
    210                 215                 220


Arg Ser Arg Arg Ala Gln Arg Ala Arg Asp Glu Tyr Arg His His Ser 
225                 230                 235                 240


Leu Arg Ala Ile Gln Lys Gly Thr Val Ala Gly Leu Ser Ser Met Phe 
                245                 250                 255


Arg Glu Leu Gly Gln Ser His Glu Gln Glu Ala Arg Leu Tyr His His 
            260                 265                 270


Leu Pro Asp Pro Gly Leu Pro Gln Pro Leu Ala Leu Pro Val Arg Thr 
        275                 280                 285


Trp Glu Arg Pro Leu Arg Pro Val Ser Arg Asp Val Ile Val Arg Trp 
    290                 295                 300


Phe Lys Glu Glu Gln Leu Pro Arg Arg Ala Gly Phe Glu Arg Asn Thr 
305                 310                 315                 320


Lys Phe Ile Ala Pro Trp Phe His Gly Gly Asn Tyr His Cys Phe Arg 
                325                 330                 335


Arg Arg Val Thr Ser Gly Thr Leu Arg Thr Glu Gly Gln Pro Thr Arg 
            340                 345                 350


Leu Pro Ser Val Val 
        355


<210>  7217
<211>  2886
<212>  DNA
<213>  Homo sapiens

<400>  7217
aaagcagccg tgccgtgtcc cagggcggga attgtgcggg gacgggctcc acggaggaat     60

cttctcttcc ttcccttgat gttgccagag gactcaggag gctctccaga tgctgcagcg    120

agtgacaagc acatccaatg gctcctaggg gcagatggcg aggtctgggt ctggatcatg    180

ggagaaggcc ctggtgacaa gccctacgaa gagatctctg aggagctgat tgcagagagg    240

gcgcggctgc aggcacagag ggaagctgag gagctctgga gacagaagga ggcagagatc    300

accaagaagt tccgggatgc tctggccaat gagaaagccc ggatcttggc ggagaagtgg    360

aaagtggaga tggaagaccg caaggctgcc aaagtcctgg aggaacgcat ccacgaggaa    420

ttcaagagga aagaggaaga ggagaggaag cgaggagaag agcagattcg cctccaggaa    480

gagcagaggg cgaaggagct ctactggacc ctgaagcagg ctcagctgca ttgccaagcc    540

agtgagaaag aggagcgaga gtgggaagaa cagttgcgcc ggtccaaggc ggctgatgag    600

gagaggagcc gccgagccca gcgcgcccgg gacgagtacc gacaccactc gctccgtgct    660

atccagaagg gcacggtcgc tggcctcagc tccatgttcc gggagcttgg ccagagccat    720

gagcaggagg caagactcta ccaccacctc cccgacccgg gtctgccgca gccccttgcc    780

ctgccggtca ggacctggga gcgcccgctg cgcccagtct ccagagatgt catcgtccgc    840

tggtttaagg aggagcagct gcctcgccga gctggcttcg agaggaacac caagttcatc    900

gccccctggt tccatggagg aaattatcac tgtttcagga ggagagttac ttcaggaacc    960

ctgcggacag agggacagcc caccagacta ccatctgttg tttgaataat ttttttcctt   1020

atcaattgga ttcattttgg tatcctgttt ttgaactcag cttaagaact tctcatctca   1080

aatcctatgg ccttctggaa gatccaccac tatccaaagg aaaaagtaga ttaatatgcc   1140

tcaagggata tgacatctat ggcatagggc tactggtctc atcccagcga tcgggacaga   1200

aattgctaat agctcatgca actctttcat gaagagctta gctatgacct tagaagacaa   1260

agcctgtttg tcatggctgc cgtaaaccga gctcttacag tgcgtggacc atgttttaat   1320

aatccaaaat aattccagtg ccgaaccctg aatttaacat atggtagaca ttcagtaaat   1380

gtttgttgaa tgaatgcatg tcttctaaaa gttttccaac acaaattagc agtggtttct   1440

tgtaaattat ttcctactcg ccactctata aaatcatggc aataatagaa gattatgaag   1500

gatttctatg gaggacataa atgctgcatc tttcataatc tccattatca ccctcattga   1560

tattatcatt ggaattatct aaggtgagcc ccagtttcca gggcagctga ttgacaccgt   1620

cctgccttcc ttatttaacc tcttcttttg ccactcgcct ctatctttga atcatatttt   1680

ggccttggtt ttgcaatggt tttatgtcat cctacagatg tcttcaagac ctggggtgag   1740

ttatcaatgc aagaatggtt cttagaaatc tgatgaggcc tctgctctct gggatgtggc   1800

cctctctatg caggttactc caatgattag ctctgtcctc attgtccttt taattccctt   1860

gtcaacttaa tctcagtatg ttgcttatat taacaagaag actcacgcaa taactcctcg   1920

ataactctca gtgatggtat ctgttggtgc atacttgtgt tccacagtta tggccatata   1980

cacagaggta gtatatgatg aagagaagat tacagtcttt acagtcaaga agacttgggt   2040

tcatatccta accctggaac ttactagcat tataatgctt gcagcattgt gtttggtgag   2100

aggaaaagaa tgaatggatt ctaggaatgt tagggaacga tttactttac ccgatggctg   2160

tatcaaacat ctatgcccca cttcttctct tgcctcacct attccttaga ttcttggtca   2220

cttctctacc acaagccacc agcactataa ccagttttgc gtgggttctg ctcttcctcc   2280

ctatgttgat cagtgtcatg tgagcataag ccaatggtag cttgccacat gccccatctc   2340

ccattgctgc agaggcataa gacagaagag atgggaagtg aatgcccgat gtggtgaatc   2400

tgggatgaat gggagtcata ggctggtaga tcgctttttc ctccttcttc ctcctggagg   2460

aactattctg agagtcatct gtttgtatgg tcttgtagaa gacagtcctg taagatcgag   2520

caaccagtca tgatgaaacc aagtggtggc cggatcagta tgacaccctg ctgcccccgt   2580

ttttaattct tctctgcctt gccctgctct ctcctgttgc tctgggattg cacttctgaa   2640

tgaagtagca gctcataagc ttttgccaca ggctctgtct tttggggaat ccaggataag   2700

aacccattat acagaagtgt tcaataatat caattttgca actcactcag ctccatggct   2760

tcccccggtc tacctgtctc actacatgca taaagtgaaa tgatggaagg aatctgcttt   2820

ctgaactcta atgtgccttc attgattatc attaaaatta tcattaaaat tgccttattt   2880

ctatgg                                                              2886


<210>  7218
<211>  308
<212>  PRT
<213>  Homo sapiens

<400>  7218

Met Leu Pro Glu Asp Ser Gly Gly Ser Pro Asp Ala Ala Ala Ser Asp 
1               5                   10                  15


Lys His Ile Gln Trp Leu Leu Gly Ala Asp Gly Glu Val Trp Val Trp 
            20                  25                  30


Ile Met Gly Glu Gly Pro Gly Asp Lys Pro Tyr Glu Glu Ile Ser Glu 
        35                  40                  45


Glu Leu Ile Ala Glu Arg Ala Arg Leu Gln Ala Gln Arg Glu Ala Glu 
    50                  55                  60


Glu Leu Trp Arg Gln Lys Glu Ala Glu Ile Thr Lys Lys Phe Arg Asp 
65                  70                  75                  80


Ala Leu Ala Asn Glu Lys Ala Arg Ile Leu Ala Glu Lys Trp Lys Val 
                85                  90                  95


Glu Met Glu Asp Arg Lys Ala Ala Lys Val Leu Glu Glu Arg Ile His 
            100                 105                 110


Glu Glu Phe Lys Arg Lys Glu Glu Glu Glu Arg Lys Arg Gly Glu Glu 
        115                 120                 125


Gln Ile Arg Leu Gln Glu Glu Gln Arg Ala Lys Glu Leu Tyr Trp Thr 
    130                 135                 140


Leu Lys Gln Ala Gln Leu His Cys Gln Ala Ser Glu Lys Glu Glu Arg 
145                 150                 155                 160


Glu Trp Glu Glu Gln Leu Arg Arg Ser Lys Ala Ala Asp Glu Glu Arg 
                165                 170                 175


Ser Arg Arg Ala Gln Arg Ala Arg Asp Glu Tyr Arg His His Ser Leu 
            180                 185                 190


Arg Ala Ile Gln Lys Gly Thr Val Ala Gly Leu Ser Ser Met Phe Arg 
        195                 200                 205


Glu Leu Gly Gln Ser His Glu Gln Glu Ala Arg Leu Tyr His His Leu 
    210                 215                 220


Pro Asp Pro Gly Leu Pro Gln Pro Leu Ala Leu Pro Val Arg Thr Trp 
225                 230                 235                 240


Glu Arg Pro Leu Arg Pro Val Ser Arg Asp Val Ile Val Arg Trp Phe 
                245                 250                 255


Lys Glu Glu Gln Leu Pro Arg Arg Ala Gly Phe Glu Arg Asn Thr Lys 
            260                 265                 270


Phe Ile Ala Pro Trp Phe His Gly Gly Asn Tyr His Cys Phe Arg Arg 
        275                 280                 285


Arg Val Thr Ser Gly Thr Leu Arg Thr Glu Gly Gln Pro Thr Arg Leu 
    290                 295                 300


Pro Ser Val Val 
305


<210>  7219
<211>  2119
<212>  DNA
<213>  Homo sapiens

<400>  7219
ggcgtgctcc caggcttaga aacaaacgag cgacgtgaca caagaggtcc caagggagca     60

aacctgaaag ccagagcctc ctgaatacac aaactgccgg tgggccagat gacattagac    120

actcctgaga tacgagaagc atcacttcct tcagacagag tcgggtcttg ctctctcacc    180

caggctggag tagagtgaca atgaccactg cagcctccac ctcctaggct caagtgatcc    240

tcctgcttca gcacccccac accaggcaac ataacaagac ccccatctct acaaaaaatt    300

aaaaaagaat tatcaggtca gatcctggca gcagctgcag cggctctcct tgccatctcc    360

ttttcacttc tggaaacatg ggctcccatg tggctgtctt tgatgatgtc atcaaggtgt    420

tcagtgacat gaaagtgtgc aagtcttcaa cactagaaaa ggtgaagaag cgcaagaagt    480

tgctgctctt ctgcctgagt gagtacaaga agtacatcat ccttgcggag gccaagaaga    540

tcctggtaag taatgtggac caaaccattg atgatcccta tgccactttt gtcaagatgc    600

tgacagtaag gactgccgct acgcccctta tgacgccacc aaggacagca agaagaagga    660

cctggtgttt atcttctggg cctctgagtc tgcatccatt aagagcaaaa tgatctatgc    720

cagctccaaa gacgtcatca agaagcagct aggggtcagc actgtcgtct tcttggaggg    780

caaactttgt gatcccctcc agcgcccttc ctggagaatc tactagtccc agacctgccc    840

tcagggattg caggctgccc ccttcctgcc agactggagg gcctggggga atcccagcag    900

agggaaggca ctcccttcac cccaattgcc aaacagcccc ccaactccct ggattttcct    960

cctctctcca tccctgacag ttctggcctt cccaaactgc ttggatcttc tgattcctct   1020

tgggttgaag cagaccaagt tctcccagga accccagttg gggaaggcct atatatatat   1080

tttaaaaaca accccactct ccacctgttc ctccaccttc ccatgctaca acttctaacc   1140

acaacagtga ctctgtgcct gtctgtttag ttctgtgtat aaatggaatg ttgtgaagat   1200

ggccccttcc catgccagct ggttcctctc ccttggttat ggccgctaat ggaaaccgga   1260

ctagtgagcg acctttaatt tttaaaaaaa gaaaatacaa taaaataata ctcaaatgtt   1320

taagcagatt tcccaaaaca gagtagaata gaattcatat gaataagcaa acaatttaat   1380

tgttactact ggcattatgt tatggatttt gctttcctac agaaaataac tccacaactg   1440

attttattag tatagaatta atttcttgct aagagtcatt tttgcttatc tcaccattgg   1500

atatttgcaa agtcactaat atttctttta tccatcattc atatgtaagt aaatatgtac   1560

cttacttcct ctttccaggc aagtagaggt tccaaatata gccatgtgtc acataacagg   1620

gatttgttct gataaacgaa tccatagaca attttgtctt tgtgcaaaca tgataaagtg   1680

tacttgcaca aacctagatg gtgtagccca ctacacacct aagctatgtg gtatagcctg   1740

ttgcttctag gctacaaaca tgtacagcat gttactatac tgagtactgt aggcaagtgt   1800

aacataatgg tcagtatttg tgtatctaaa catacctaaa tatagaaaag gtacagtaaa   1860

aatatggtat aaaagataaa tggtatacct gtataaggca tttaccatga atggagcttg   1920

caggactgga agttgctctg ggtgagtcaa tgagtgagtg gtgagtcact gtgaaagcct   1980

aggacattat tgtacactac tgtaaactgc ataaacactg cacactaggc tacaatttat   2040

gaaaaaattt cttcaataat aagctattaa ataacataaa gttgtaaata ataataaatt   2100

atgattacat atcaacaat                                                2119


<210>  7220
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  7220

Met Gly Ser His Val Ala Val Phe Asp Asp Val Ile Lys Val Phe Ser 
1               5                   10                  15


Asp Met Lys Val Cys Lys Ser Ser Thr Leu Glu Lys Val Lys Lys Arg 
            20                  25                  30


Lys Lys Leu Leu Leu Phe Cys Leu Ser Glu Tyr Lys Lys Tyr Ile Ile 
        35                  40                  45


Leu Ala Glu Ala Lys Lys Ile Leu Val Ser Asn Val Asp Gln Thr Ile 
    50                  55                  60


Asp Asp Pro Tyr Ala Thr Phe Val Lys Met Leu Thr Val Arg Thr Ala 
65                  70                  75                  80


Ala Thr Pro Leu Met Thr Pro Pro Arg Thr Ala Arg Arg Arg Thr Trp 
                85                  90                  95


Cys Leu Ser Ser Gly Pro Leu Ser Leu His Pro Leu Arg Ala Lys 
            100                 105                 110


<210>  7221
<211>  2321
<212>  DNA
<213>  Homo sapiens

<400>  7221
taccgccccc tgccctgccc tgccctcccc tcgcccggcg cggtcccgtc cgcctctcgc     60

tcgcctcccg cctcccctcg gtcttccgag gcgcccgggc tcccggcgcg gcggcggagg    120

gggcgggcag gccggcgggc ggtgatgtgg cgggactctt tatgcgctgc ggcaggatac    180

gcgctcggcg ctgggacgcg actgcgctca gttctctcct ctcggaagct gcagccatga    240

tggaagtttg agagttgagc cgctgtgagg cgaggccggg ctcaggcgag ggagatgaga    300

gacggcggcg gccgcggccc ggagcccctc tcagcgcctg tgagcagccg cgggggcagc    360

gccctcgggg agccggccgg cctgcggcgg cggcagcggc ggcgtttctc gcctcctctt    420

cgtcttttct aaccgtgcag cctcttcctc ggcttctcct gaaagggaag gtggaagccg    480

tgggctcggg cgggagccgg ctgaggcgcg gcggcggcgg cggcacctcc cgctcctgga    540

gcggggggga gaagcggcgg cggcggcggc cgcggcggct gcagctccag ggagggggtc    600

tgagtcgcct gtcaccattt ccagggctgg gaacgccgga gagttggtct ctccccttct    660

actgcctcca acacggcggc ggcggcggct ggcacatcca gggacccggg ccggttttaa    720

acctcccgtg cgccgccgcc gcaccccccg tggcccgggc tccggaggcc gccggcggag    780

gcagccgttc ggaggattat tcgtcttctc cccattccgc tgccgccgct gccaggcctc    840

tggctgctga ggagaagcag gcccagtcgc tgcaaccatc cagcagccgc cgcagcagcc    900

attacccggc tgcggtccag agccaagcgg cggcagagcg aggggcatca gctaccgcca    960

agtccagagc catttccatc ctgcagaaga agccccgcca ccagcagctt ctgccatctc   1020

tctcctcctt tttcttcagc cacaggctcc cagacatgac agccatcatc aaagagatcg   1080

ttagcagaaa caaaaggaga tatcaagagg atggattcga cttagacttg acctatattt   1140

atccaaacat tattgctatg ggatttcctg cagaaagact tgaaggcgta tacaggaaca   1200

atattgatga tgtagtaagg tttttggatt caaagcataa aaaccattac aagatataca   1260

atctttgtgc tgaaagacat tatgacaccg ccaaatttaa ttgcagagtt gcacaatatc   1320

cttttgaaga ccataaccca ccacagctag aacttatcaa acccttttgt gaagatcttg   1380

accaatggct aagtgaagat gacaatcatg ttgcagcaat tcactgtaaa gctggaaagg   1440

gacgaactgg tgtaatgata tgtgcatatt tattacatcg gggcaaattt ttaaaggcac   1500

aagaggccct agatttctat ggggaagtaa ggaccagaga caaaaaggga gtaactattc   1560

ccagtcagag gcgctatgtg tattattata gctacctgtt aaagaatcat ctggattata   1620

gaccagtggc actgttgttt cacaagatga tgtttgaaac tattccaatg ttcagtggcg   1680

gaacttgcaa tcctcagttt gtggtctgcc agctaaaggt gaagatatat tcctccaatt   1740

caggacccac acgacgggaa gacaagttca tgtactttga gttccctcag ccgttacctg   1800

tgtgtggtga tatcaaagta gagttcttcc acaaacagaa caagatgcta aaaaaggaca   1860

aaatgtttca cttttgggta aatacattct tcataccagg accagaggaa acctcagaaa   1920

aagtagaaaa tggaagtcta tgtgatcaag aaatcgatag catttgcagt atagagcgtg   1980

cagataatga caaggaatat ctagtactta ctttaacaaa aaatgatctt gacaaagcaa   2040

ataaagacaa agccaaccga tacttttctc caaattttaa ggtgaagctg tacttcacaa   2100

aaacagtaga ggagccgtca aatccagagg ctagcagttc aacttctgta acaccagatg   2160

ttagtgacaa tgaacctgat cattatagat attctgacac cactgactct gatccagaga   2220

atgaaccttt tgatgaagat cagcatacac aaattacaaa agtctgaatt tttttttatc   2280

aagagggata aaacaccatg aaaataaact tgaataaact g                       2321


<210>  7222
<211>  403
<212>  PRT
<213>  Homo sapiens

<400>  7222

Met Thr Ala Ile Ile Lys Glu Ile Val Ser Arg Asn Lys Arg Arg Tyr 
1               5                   10                  15


Gln Glu Asp Gly Phe Asp Leu Asp Leu Thr Tyr Ile Tyr Pro Asn Ile 
            20                  25                  30


Ile Ala Met Gly Phe Pro Ala Glu Arg Leu Glu Gly Val Tyr Arg Asn 
        35                  40                  45


Asn Ile Asp Asp Val Val Arg Phe Leu Asp Ser Lys His Lys Asn His 
    50                  55                  60


Tyr Lys Ile Tyr Asn Leu Cys Ala Glu Arg His Tyr Asp Thr Ala Lys 
65                  70                  75                  80


Phe Asn Cys Arg Val Ala Gln Tyr Pro Phe Glu Asp His Asn Pro Pro 
                85                  90                  95


Gln Leu Glu Leu Ile Lys Pro Phe Cys Glu Asp Leu Asp Gln Trp Leu 
            100                 105                 110


Ser Glu Asp Asp Asn His Val Ala Ala Ile His Cys Lys Ala Gly Lys 
        115                 120                 125


Gly Arg Thr Gly Val Met Ile Cys Ala Tyr Leu Leu His Arg Gly Lys 
    130                 135                 140


Phe Leu Lys Ala Gln Glu Ala Leu Asp Phe Tyr Gly Glu Val Arg Thr 
145                 150                 155                 160


Arg Asp Lys Lys Gly Val Thr Ile Pro Ser Gln Arg Arg Tyr Val Tyr 
                165                 170                 175


Tyr Tyr Ser Tyr Leu Leu Lys Asn His Leu Asp Tyr Arg Pro Val Ala 
            180                 185                 190


Leu Leu Phe His Lys Met Met Phe Glu Thr Ile Pro Met Phe Ser Gly 
        195                 200                 205


Gly Thr Cys Asn Pro Gln Phe Val Val Cys Gln Leu Lys Val Lys Ile 
    210                 215                 220


Tyr Ser Ser Asn Ser Gly Pro Thr Arg Arg Glu Asp Lys Phe Met Tyr 
225                 230                 235                 240


Phe Glu Phe Pro Gln Pro Leu Pro Val Cys Gly Asp Ile Lys Val Glu 
                245                 250                 255


Phe Phe His Lys Gln Asn Lys Met Leu Lys Lys Asp Lys Met Phe His 
            260                 265                 270


Phe Trp Val Asn Thr Phe Phe Ile Pro Gly Pro Glu Glu Thr Ser Glu 
        275                 280                 285


Lys Val Glu Asn Gly Ser Leu Cys Asp Gln Glu Ile Asp Ser Ile Cys 
    290                 295                 300


Ser Ile Glu Arg Ala Asp Asn Asp Lys Glu Tyr Leu Val Leu Thr Leu 
305                 310                 315                 320


Thr Lys Asn Asp Leu Asp Lys Ala Asn Lys Asp Lys Ala Asn Arg Tyr 
                325                 330                 335


Phe Ser Pro Asn Phe Lys Val Lys Leu Tyr Phe Thr Lys Thr Val Glu 
            340                 345                 350


Glu Pro Ser Asn Pro Glu Ala Ser Ser Ser Thr Ser Val Thr Pro Asp 
        355                 360                 365


Val Ser Asp Asn Glu Pro Asp His Tyr Arg Tyr Ser Asp Thr Thr Asp 
    370                 375                 380


Ser Asp Pro Glu Asn Glu Pro Phe Asp Glu Asp Gln His Thr Gln Ile 
385                 390                 395                 400


Thr Lys Val 



<210>  7223
<211>  2583
<212>  DNA
<213>  Homo sapiens

<400>  7223
taccgccccc tgccctgccc tgccctcccc tcgcccggcg cggtcccgtc cgcctctcgc     60

tcgcctcccg cctcccctcg gtcttccgag gcgcccgggc tcccggcgcg gcggcggagg    120

gggcgggcag gccggcgggc ggtgatgtgg cgggactctt tatgcgctgc ggcaggatac    180

gcgctcggcg ctgggacgcg actgcgctca gttctctcct ctcggaagct gcagccatga    240

tggaagtttg agagttgagc cgctgtgagg cgaggccggg ctcaggcgag ggagatgaga    300

gacggcggcg gccgcggccc ggagcccctc tcagcgcctg tgagcagccg cgggggcagc    360

gccctcgggg agccggccgg cctgcggcgg cggcagcggc ggcgtttctc gcctcctctt    420

cgtcttttct aaccgtgcag cctcttcctc ggcttctcct gaaagggaag gtggaagccg    480

tgggctcggg cgggagccgg ctgaggcgcg gcggcggcgg cggcacctcc cgctcctgga    540

gcggggggga gaagcggcgg cggcggcggc cgcggcggct gcagctccag ggagggggtc    600

tgagtcgcct gtcaccattt ccagggctgg gaacgccgga gagttggtct ctccccttct    660

actgcctcca acacggcggc ggcggcggct ggcacatcca gggacccggg ccggttttaa    720

acctcccgtg cgccgccgcc gcaccccccg tggcccgggc tccggaggcc gccggcggag    780

gcagccgttc ggaggattat tcgtcttctc cccattccgc tgccgccgct gccaggcctc    840

tggctgctga ggagaagcag gcccagtcgc tgcaaccatc cagcagccgc cgcagcagcc    900

attacccggc tgcggtccag agccaagcgg cggcagagcg aggggcatca gctaccgcca    960

agtccagagc catttccatc ctgcagaaga agccccgcca ccagcagctt ctgccatctc   1020

tctcctcctt tttcttcagc cacaggctcc cagacatgac agccatcatc aaagagatcg   1080

ttagcagaaa caaaaggaga tatcaagagg atggattcga cttagacttg acctatattt   1140

atccaaacat tattgctatg ggatttcctg cagaaagact tgaaggcgta tacaggaaca   1200

atattgatga tgtagtaagg tttttggatt caaagcataa aaaccattac aagatataca   1260

atctttgtgc tgaaagacat tatgacaccg ccaaatttaa ttgcagagtt gcacaatatc   1320

cttttgaaga ccataaccca ccacagctag aacttatcaa acccttttgt gaagatcttg   1380

accaatggct aagtgaagat gacaatcatg ttgcagcaat tcactgtaaa gctggaaagg   1440

gacgaactgg tgtaatgata tgtgcatatt tattacatcg gggcaaattt ttaaaggcac   1500

aagaggccct agatttctat ggggaagtaa ggaccagaga caaaaaggga gtaactattc   1560

ccagtcagag gcgctatgtg tattattata gctacctgtt aaagaatcat ctggattata   1620

gaccagtggc actgttgttt cacaagatga tgtttgaaac tattccaatg ttcagtggcg   1680

gaacttgcaa tcctcagttt gtggtctgcc agctaaaggt gaagatatat tcctccaatt   1740

caggacccac acgacgggaa gacaagttca tgtactttga gttccctcag ccgttacctg   1800

tgtgtggtga tatcaaagta gagttcttcc acaaacagaa caagatgcta aaaaaggaca   1860

aaatgtttca cttttgggta aatacattct tcataccagg accagaggaa acctcagaaa   1920

aagtagaaaa tggaagtcta tgtgatcaag aaatcgatag catttgcagt atagagcgtg   1980

cagataatga caaggaatat ctagtactta ctttaacaaa aaatgatctt gacaaagcaa   2040

ataaagacaa agccaaccga tacttttctc caaattttaa ggtgaagctg tacttcacaa   2100

aaacagtaga ggagccgtca aatccagagg ctagcagttc aacttctgta acaccagatg   2160

ttagtgacaa tgaacctgat cattatagat attctgacac cactgactct gatccagaga   2220

atgaaccttt tgatgaagat cagcatacac aaattacaaa agtctgaatt tttttttatc   2280

aagagggata aaacaccatg aaaataaact tgaataaact gaaaatggac cttttttttt   2340

ttaatggcaa taggacattg tgtcagatta ccagttatag gaacaattct cttttcctga   2400

ccaatcttgt tttaccctat acatccacag ggttttgaca cttgttgtcc agttgaaaaa   2460

aggttgtgta gctgtgtcat gtatatacct ttttgtgtca aaaggacatt taaaattcaa   2520

ttaggattaa taaagatggc actttcccgt tttattccag ttttataaaa agtggagaca   2580

gac                                                                 2583


<210>  7224
<211>  403
<212>  PRT
<213>  Homo sapiens

<400>  7224

Met Thr Ala Ile Ile Lys Glu Ile Val Ser Arg Asn Lys Arg Arg Tyr 
1               5                   10                  15


Gln Glu Asp Gly Phe Asp Leu Asp Leu Thr Tyr Ile Tyr Pro Asn Ile 
            20                  25                  30


Ile Ala Met Gly Phe Pro Ala Glu Arg Leu Glu Gly Val Tyr Arg Asn 
        35                  40                  45


Asn Ile Asp Asp Val Val Arg Phe Leu Asp Ser Lys His Lys Asn His 
    50                  55                  60


Tyr Lys Ile Tyr Asn Leu Cys Ala Glu Arg His Tyr Asp Thr Ala Lys 
65                  70                  75                  80


Phe Asn Cys Arg Val Ala Gln Tyr Pro Phe Glu Asp His Asn Pro Pro 
                85                  90                  95


Gln Leu Glu Leu Ile Lys Pro Phe Cys Glu Asp Leu Asp Gln Trp Leu 
            100                 105                 110


Ser Glu Asp Asp Asn His Val Ala Ala Ile His Cys Lys Ala Gly Lys 
        115                 120                 125


Gly Arg Thr Gly Val Met Ile Cys Ala Tyr Leu Leu His Arg Gly Lys 
    130                 135                 140


Phe Leu Lys Ala Gln Glu Ala Leu Asp Phe Tyr Gly Glu Val Arg Thr 
145                 150                 155                 160


Arg Asp Lys Lys Gly Val Thr Ile Pro Ser Gln Arg Arg Tyr Val Tyr 
                165                 170                 175


Tyr Tyr Ser Tyr Leu Leu Lys Asn His Leu Asp Tyr Arg Pro Val Ala 
            180                 185                 190


Leu Leu Phe His Lys Met Met Phe Glu Thr Ile Pro Met Phe Ser Gly 
        195                 200                 205


Gly Thr Cys Asn Pro Gln Phe Val Val Cys Gln Leu Lys Val Lys Ile 
    210                 215                 220


Tyr Ser Ser Asn Ser Gly Pro Thr Arg Arg Glu Asp Lys Phe Met Tyr 
225                 230                 235                 240


Phe Glu Phe Pro Gln Pro Leu Pro Val Cys Gly Asp Ile Lys Val Glu 
                245                 250                 255


Phe Phe His Lys Gln Asn Lys Met Leu Lys Lys Asp Lys Met Phe His 
            260                 265                 270


Phe Trp Val Asn Thr Phe Phe Ile Pro Gly Pro Glu Glu Thr Ser Glu 
        275                 280                 285


Lys Val Glu Asn Gly Ser Leu Cys Asp Gln Glu Ile Asp Ser Ile Cys 
    290                 295                 300


Ser Ile Glu Arg Ala Asp Asn Asp Lys Glu Tyr Leu Val Leu Thr Leu 
305                 310                 315                 320


Thr Lys Asn Asp Leu Asp Lys Ala Asn Lys Asp Lys Ala Asn Arg Tyr 
                325                 330                 335


Phe Ser Pro Asn Phe Lys Val Lys Leu Tyr Phe Thr Lys Thr Val Glu 
            340                 345                 350


Glu Pro Ser Asn Pro Glu Ala Ser Ser Ser Thr Ser Val Thr Pro Asp 
        355                 360                 365


Val Ser Asp Asn Glu Pro Asp His Tyr Arg Tyr Ser Asp Thr Thr Asp 
    370                 375                 380


Ser Asp Pro Glu Asn Glu Pro Phe Asp Glu Asp Gln His Thr Gln Ile 
385                 390                 395                 400


Thr Lys Val 



<210>  7225
<211>  3169
<212>  DNA
<213>  Homo sapiens

<400>  7225
taccgccccc tgccctgccc tgccctcccc tcgcccggcg cggtcccgtc cgcctctcgc     60

tcgcctcccg cctcccctcg gtcttccgag gcgcccgggc tcccggcgcg gcggcggagg    120

gggcgggcag gccggcgggc ggtgatgtgg cgggactctt tatgcgctgc ggcaggatac    180

gcgctcggcg ctgggacgcg actgcgctca gttctctcct ctcggaagct gcagccatga    240

tggaagtttg agagttgagc cgctgtgagg cgaggccggg ctcaggcgag ggagatgaga    300

gacggcggcg gccgcggccc ggagcccctc tcagcgcctg tgagcagccg cgggggcagc    360

gccctcgggg agccggccgg cctgcggcgg cggcagcggc ggcgtttctc gcctcctctt    420

cgtcttttct aaccgtgcag cctcttcctc ggcttctcct gaaagggaag gtggaagccg    480

tgggctcggg cgggagccgg ctgaggcgcg gcggcggcgg cggcacctcc cgctcctgga    540

gcggggggga gaagcggcgg cggcggcggc cgcggcggct gcagctccag ggagggggtc    600

tgagtcgcct gtcaccattt ccagggctgg gaacgccgga gagttggtct ctccccttct    660

actgcctcca acacggcggc ggcggcggct ggcacatcca gggacccggg ccggttttaa    720

acctcccgtg cgccgccgcc gcaccccccg tggcccgggc tccggaggcc gccggcggag    780

gcagccgttc ggaggattat tcgtcttctc cccattccgc tgccgccgct gccaggcctc    840

tggctgctga ggagaagcag gcccagtcgc tgcaaccatc cagcagccgc cgcagcagcc    900

attacccggc tgcggtccag agccaagcgg cggcagagcg aggggcatca gctaccgcca    960

agtccagagc catttccatc ctgcagaaga agccccgcca ccagcagctt ctgccatctc   1020

tctcctcctt tttcttcagc cacaggctcc cagacatgac agccatcatc aaagagatcg   1080

ttagcagaaa caaaaggaga tatcaagagg atggattcga cttagacttg acctatattt   1140

atccaaacat tattgctatg ggatttcctg cagaaagact tgaaggcgta tacaggaaca   1200

atattgatga tgtagtaagg tttttggatt caaagcataa aaaccattac aagatataca   1260

atctttgtgc tgaaagacat tatgacaccg ccaaatttaa ttgcagagtt gcacaatatc   1320

cttttgaaga ccataaccca ccacagctag aacttatcaa acccttttgt gaagatcttg   1380

accaatggct aagtgaagat gacaatcatg ttgcagcaat tcactgtaaa gctggaaagg   1440

gacgaactgg tgtaatgata tgtgcatatt tattacatcg gggcaaattt ttaaaggcac   1500

aagaggccct agatttctat ggggaagtaa ggaccagaga caaaaaggga gtaactattc   1560

ccagtcagag gcgctatgtg tattattata gctacctgtt aaagaatcat ctggattata   1620

gaccagtggc actgttgttt cacaagatga tgtttgaaac tattccaatg ttcagtggcg   1680

gaacttgcaa tcctcagttt gtggtctgcc agctaaaggt gaagatatat tcctccaatt   1740

caggacccac acgacgggaa gacaagttca tgtactttga gttccctcag ccgttacctg   1800

tgtgtggtga tatcaaagta gagttcttcc acaaacagaa caagatgcta aaaaaggaca   1860

aaatgtttca cttttgggta aatacattct tcataccagg accagaggaa acctcagaaa   1920

aagtagaaaa tggaagtcta tgtgatcaag aaatcgatag catttgcagt atagagcgtg   1980

cagataatga caaggaatat ctagtactta ctttaacaaa aaatgatctt gacaaagcaa   2040

ataaagacaa agccaaccga tacttttctc caaattttaa ggtgaagctg tacttcacaa   2100

aaacagtaga ggagccgtca aatccagagg ctagcagttc aacttctgta acaccagatg   2160

ttagtgacaa tgaacctgat cattatagat attctgacac cactgactct gatccagaga   2220

atgaaccttt tgatgaagat cagcatacac aaattacaaa agtctgaatt tttttttatc   2280

aagagggata aaacaccatg aaaataaact tgaataaact gaaaatggac cttttttttt   2340

ttaatggcaa taggacattg tgtcagatta ccagttatag gaacaattct cttttcctga   2400

ccaatcttgt tttaccctat acatccacag ggttttgaca cttgttgtcc agttgaaaaa   2460

aggttgtgta gctgtgtcat gtatatacct ttttgtgtca aaaggacatt taaaattcaa   2520

ttaggattaa taaagatggc actttcccgt tttattccag ttttataaaa agtggagaca   2580

gactgatgtg tatacgtagg aattttttcc ttttgtgttc tgtcaccaac tgaagtggct   2640

aaagagcttt gtgatatact ggttcacatc ctaccccttt gcacttgtgg caacagataa   2700

gtttgcagtt ggctaagaga ggtttccgaa gggttttgct acattctaat gcatgtattc   2760

gggttagggg aatggaggga atgctcagaa aggaaataat tttatgctgg actctggacc   2820

atataccatc tccagctatt tacacacacc tttctttagc atgctacagt tattaatctg   2880

gacattcgag gaattggccg ctgtcactgc ttgttgtttg cgcatttttt tttaaagcat   2940

attggtgcta gaaaaggcag ctaaaggaag tgaatctgta ttggggtaca ggaatgaacc   3000

ttctgcaaca tcttaagatc cacaaatgaa gggatataaa aataatgtca taggtaagaa   3060

acacagcaac aatgacttaa ccatataaat gtggaggcta tcaacaaaga atgggcttga   3120

aacattataa aaattgacaa tgatttatta aatatgtttt ctcaattgt               3169


<210>  7226
<211>  403
<212>  PRT
<213>  Homo sapiens

<400>  7226

Met Thr Ala Ile Ile Lys Glu Ile Val Ser Arg Asn Lys Arg Arg Tyr 
1               5                   10                  15


Gln Glu Asp Gly Phe Asp Leu Asp Leu Thr Tyr Ile Tyr Pro Asn Ile 
            20                  25                  30


Ile Ala Met Gly Phe Pro Ala Glu Arg Leu Glu Gly Val Tyr Arg Asn 
        35                  40                  45


Asn Ile Asp Asp Val Val Arg Phe Leu Asp Ser Lys His Lys Asn His 
    50                  55                  60


Tyr Lys Ile Tyr Asn Leu Cys Ala Glu Arg His Tyr Asp Thr Ala Lys 
65                  70                  75                  80


Phe Asn Cys Arg Val Ala Gln Tyr Pro Phe Glu Asp His Asn Pro Pro 
                85                  90                  95


Gln Leu Glu Leu Ile Lys Pro Phe Cys Glu Asp Leu Asp Gln Trp Leu 
            100                 105                 110


Ser Glu Asp Asp Asn His Val Ala Ala Ile His Cys Lys Ala Gly Lys 
        115                 120                 125


Gly Arg Thr Gly Val Met Ile Cys Ala Tyr Leu Leu His Arg Gly Lys 
    130                 135                 140


Phe Leu Lys Ala Gln Glu Ala Leu Asp Phe Tyr Gly Glu Val Arg Thr 
145                 150                 155                 160


Arg Asp Lys Lys Gly Val Thr Ile Pro Ser Gln Arg Arg Tyr Val Tyr 
                165                 170                 175


Tyr Tyr Ser Tyr Leu Leu Lys Asn His Leu Asp Tyr Arg Pro Val Ala 
            180                 185                 190


Leu Leu Phe His Lys Met Met Phe Glu Thr Ile Pro Met Phe Ser Gly 
        195                 200                 205


Gly Thr Cys Asn Pro Gln Phe Val Val Cys Gln Leu Lys Val Lys Ile 
    210                 215                 220


Tyr Ser Ser Asn Ser Gly Pro Thr Arg Arg Glu Asp Lys Phe Met Tyr 
225                 230                 235                 240


Phe Glu Phe Pro Gln Pro Leu Pro Val Cys Gly Asp Ile Lys Val Glu 
                245                 250                 255


Phe Phe His Lys Gln Asn Lys Met Leu Lys Lys Asp Lys Met Phe His 
            260                 265                 270


Phe Trp Val Asn Thr Phe Phe Ile Pro Gly Pro Glu Glu Thr Ser Glu 
        275                 280                 285


Lys Val Glu Asn Gly Ser Leu Cys Asp Gln Glu Ile Asp Ser Ile Cys 
    290                 295                 300


Ser Ile Glu Arg Ala Asp Asn Asp Lys Glu Tyr Leu Val Leu Thr Leu 
305                 310                 315                 320


Thr Lys Asn Asp Leu Asp Lys Ala Asn Lys Asp Lys Ala Asn Arg Tyr 
                325                 330                 335


Phe Ser Pro Asn Phe Lys Val Lys Leu Tyr Phe Thr Lys Thr Val Glu 
            340                 345                 350


Glu Pro Ser Asn Pro Glu Ala Ser Ser Ser Thr Ser Val Thr Pro Asp 
        355                 360                 365


Val Ser Asp Asn Glu Pro Asp His Tyr Arg Tyr Ser Asp Thr Thr Asp 
    370                 375                 380


Ser Asp Pro Glu Asn Glu Pro Phe Asp Glu Asp Gln His Thr Gln Ile 
385                 390                 395                 400


Thr Lys Val 



<210>  7227
<211>  5573
<212>  DNA
<213>  Homo sapiens

<400>  7227
taccgccccc tgccctgccc tgccctcccc tcgcccggcg cggtcccgtc cgcctctcgc     60

tcgcctcccg cctcccctcg gtcttccgag gcgcccgggc tcccggcgcg gcggcggagg    120

gggcgggcag gccggcgggc ggtgatgtgg cgggactctt tatgcgctgc ggcaggatac    180

gcgctcggcg ctgggacgcg actgcgctca gttctctcct ctcggaagct gcagccatga    240

tggaagtttg agagttgagc cgctgtgagg cgaggccggg ctcaggcgag ggagatgaga    300

gacggcggcg gccgcggccc ggagcccctc tcagcgcctg tgagcagccg cgggggcagc    360

gccctcgggg agccggccgg cctgcggcgg cggcagcggc ggcgtttctc gcctcctctt    420

cgtcttttct aaccgtgcag cctcttcctc ggcttctcct gaaagggaag gtggaagccg    480

tgggctcggg cgggagccgg ctgaggcgcg gcggcggcgg cggcacctcc cgctcctgga    540

gcggggggga gaagcggcgg cggcggcggc cgcggcggct gcagctccag ggagggggtc    600

tgagtcgcct gtcaccattt ccagggctgg gaacgccgga gagttggtct ctccccttct    660

actgcctcca acacggcggc ggcggcggct ggcacatcca gggacccggg ccggttttaa    720

acctcccgtg cgccgccgcc gcaccccccg tggcccgggc tccggaggcc gccggcggag    780

gcagccgttc ggaggattat tcgtcttctc cccattccgc tgccgccgct gccaggcctc    840

tggctgctga ggagaagcag gcccagtcgc tgcaaccatc cagcagccgc cgcagcagcc    900

attacccggc tgcggtccag agccaagcgg cggcagagcg aggggcatca gctaccgcca    960

agtccagagc catttccatc ctgcagaaga agccccgcca ccagcagctt ctgccatctc   1020

tctcctcctt tttcttcagc cacaggctcc cagacatgac agccatcatc aaagagatcg   1080

ttagcagaaa caaaaggaga tatcaagagg atggattcga cttagacttg acctatattt   1140

atccaaacat tattgctatg ggatttcctg cagaaagact tgaaggcgta tacaggaaca   1200

atattgatga tgtagtaagg tttttggatt caaagcataa aaaccattac aagatataca   1260

atctttgtgc tgaaagacat tatgacaccg ccaaatttaa ttgcagagtt gcacaatatc   1320

cttttgaaga ccataaccca ccacagctag aacttatcaa acccttttgt gaagatcttg   1380

accaatggct aagtgaagat gacaatcatg ttgcagcaat tcactgtaaa gctggaaagg   1440

gacgaactgg tgtaatgata tgtgcatatt tattacatcg gggcaaattt ttaaaggcac   1500

aagaggccct agatttctat ggggaagtaa ggaccagaga caaaaaggga gtaactattc   1560

ccagtcagag gcgctatgtg tattattata gctacctgtt aaagaatcat ctggattata   1620

gaccagtggc actgttgttt cacaagatga tgtttgaaac tattccaatg ttcagtggcg   1680

gaacttgcaa tcctcagttt gtggtctgcc agctaaaggt gaagatatat tcctccaatt   1740

caggacccac acgacgggaa gacaagttca tgtactttga gttccctcag ccgttacctg   1800

tgtgtggtga tatcaaagta gagttcttcc acaaacagaa caagatgcta aaaaaggaca   1860

aaatgtttca cttttgggta aatacattct tcataccagg accagaggaa acctcagaaa   1920

aagtagaaaa tggaagtcta tgtgatcaag aaatcgatag catttgcagt atagagcgtg   1980

cagataatga caaggaatat ctagtactta ctttaacaaa aaatgatctt gacaaagcaa   2040

ataaagacaa agccaaccga tacttttctc caaattttaa ggtgaagctg tacttcacaa   2100

aaacagtaga ggagccgtca aatccagagg ctagcagttc aacttctgta acaccagatg   2160

ttagtgacaa tgaacctgat cattatagat attctgacac cactgactct gatccagaga   2220

atgaaccttt tgatgaagat cagcatacac aaattacaaa agtctgaatt tttttttatc   2280

aagagggata aaacaccatg aaaataaact tgaataaact gaaaatggac cttttttttt   2340

ttaatggcaa taggacattg tgtcagatta ccagttatag gaacaattct cttttcctga   2400

ccaatcttgt tttaccctat acatccacag ggttttgaca cttgttgtcc agttgaaaaa   2460

aggttgtgta gctgtgtcat gtatatacct ttttgtgtca aaaggacatt taaaattcaa   2520

ttaggattaa taaagatggc actttcccgt tttattccag ttttataaaa agtggagaca   2580

gactgatgtg tatacgtagg aattttttcc ttttgtgttc tgtcaccaac tgaagtggct   2640

aaagagcttt gtgatatact ggttcacatc ctaccccttt gcacttgtgg caacagataa   2700

gtttgcagtt ggctaagaga ggtttccgaa gggttttgct acattctaat gcatgtattc   2760

gggttagggg aatggaggga atgctcagaa aggaaataat tttatgctgg actctggacc   2820

atataccatc tccagctatt tacacacacc tttctttagc atgctacagt tattaatctg   2880

gacattcgag gaattggccg ctgtcactgc ttgttgtttg cgcatttttt tttaaagcat   2940

attggtgcta gaaaaggcag ctaaaggaag tgaatctgta ttggggtaca ggaatgaacc   3000

ttctgcaaca tcttaagatc cacaaatgaa gggatataaa aataatgtca taggtaagaa   3060

acacagcaac aatgacttaa ccatataaat gtggaggcta tcaacaaaga atgggcttga   3120

aacattataa aaattgacaa tgatttatta aatatgtttt ctcaattgta acgacttctc   3180

catctcctgt gtaatcaagg ccagtgctaa aattcagatg ctgttagtac ctacatcagt   3240

caacaactta cacttatttt actagttttc aatcataata cctgctgtgg atgcttcatg   3300

tgctgcctgc aagcttcttt tttctcatta aatataaaat attttgtaat gctgcacaga   3360

aattttcaat ttgagattct acagtaagcg ttttttttct ttgaagattt atgatgcact   3420

tattcaatag ctgtcagccg ttccaccctt ttgaccttac acattctatt acaatgaatt   3480

ttgcagtttt gcacattttt taaatgtcat taactgttag ggaattttac ttgaatactg   3540

aatacatata atgtttatat taaaaaggac atttgtgtta aaaaggaaat tagagttgca   3600

gtaaactttc aatgctgcac acaaaaaaaa gacatttgat ttttcagtag aaattgtcct   3660

acatgtgctt tattgatttg ctattgaaag aatagggttt tttttttttt tttttttttt   3720

ttttttaaat gtgcagtgtt gaatcatttc ttcatagtgc tcccccgagt tgggactagg   3780

gcttcaattt cacttcttaa aaaaaatcat catatatttg atatgcccag actgcatacg   3840

attttaagcg gagtacaact actattgtaa agctaatgtg aagatattat taaaaaggtt   3900

tttttttcca gaaatttggt gtcttcaaat tataccttca ccttgacatt tgaatatcca   3960

gccattttgt ttcttaatgg tataaaattc cattttcaat aacttattgg tgctgaaatt   4020

gttcactagc tgtggtctga cctagttaat ttacaaatac agattgaata ggacctacta   4080

gagcagcatt tatagagttt gatggcaaat agattaggca gaacttcatc taaaatattc   4140

ttagtaaata atgttgacac gttttccata ccttgtcagt ttcattcaac aatttttaaa   4200

tttttaacaa agctcttagg atttacacat ttatatttaa acattgatat atagagtatt   4260

gattgattgc tcataagtta aattggtaaa gttagagaca actattctaa cacctcacca   4320

ttgaaattta tatgccacct tgtctttcat aaaagctgaa aattgttacc taaaatgaaa   4380

atcaacttca tgttttgaag atagttataa atattgttct ttgttacaat ttcgggcacc   4440

gcatattaaa acgtaacttt attgttccaa tatgtaacat ggagggccag gtcataaata   4500

atgacattat aatgggcttt tgcactgtta ttatttttcc tttggaatgt gaaggtctga   4560

atgagggttt tgattttgaa tgtttcaatg tttttgagaa gccttgctta cattttatgg   4620

tgtagtcatt ggaaatggaa aaatggcatt atatatatta tatatataaa tatatattat   4680

acatactctc cttactttat ttcagttacc atccccatag aatttgacaa gaattgctat   4740

gactgaaagg ttttcgagtc ctaattaaaa ctttatttat ggcagtattc ataattagcc   4800

tgaaatgcat tctgtaggta atctctgagt ttctggaata ttttcttaga ctttttggat   4860

gtgcagcagc ttacatgtct gaagttactt gaaggcatca cttttaagaa agcttacagt   4920

tgggccctgt accatcccaa gtcctttgta gctcctcttg aacatgtttg ccatactttt   4980

aaaagggtag ttgaataaat agcatcacca ttctttgctg tggcacaggt tataaactta   5040

agtggagttt accggcagca tcaaatgttt cagctttaaa aaataaaagt agggtacaag   5100

tttaatgttt agttctagaa attttgtgca atatgttcat aacgatggct gtggttgcca   5160

caaagtgcct cgtttacctt taaatactgt taatgtgtca tgcatgcaga tggaaggggt   5220

ggaactgtgc actaaagtgg gggctttaac tgtagtattt ggcagagttg ccttctacct   5280

gccagttcaa aagttcaacc tgttttcata tagaatatat atactaaaaa atttcagtct   5340

gttaaacagc cttactctga ttcagcctct tcagatactc ttgtgctgtg cagcagtggc   5400

tctgtgtgta aatgctatgc actgaggata cacaaaaata ccaatatgat gtgtacagga   5460

taatgcctca tcccaatcag atgtccattt gttattgtgt ttgttaacaa ccctttatct   5520

cttagtgtta taaactccac ttaaaactga ttaaagtctc attcttgtca ttg          5573


<210>  7228
<211>  403
<212>  PRT
<213>  Homo sapiens

<400>  7228

Met Thr Ala Ile Ile Lys Glu Ile Val Ser Arg Asn Lys Arg Arg Tyr 
1               5                   10                  15


Gln Glu Asp Gly Phe Asp Leu Asp Leu Thr Tyr Ile Tyr Pro Asn Ile 
            20                  25                  30


Ile Ala Met Gly Phe Pro Ala Glu Arg Leu Glu Gly Val Tyr Arg Asn 
        35                  40                  45


Asn Ile Asp Asp Val Val Arg Phe Leu Asp Ser Lys His Lys Asn His 
    50                  55                  60


Tyr Lys Ile Tyr Asn Leu Cys Ala Glu Arg His Tyr Asp Thr Ala Lys 
65                  70                  75                  80


Phe Asn Cys Arg Val Ala Gln Tyr Pro Phe Glu Asp His Asn Pro Pro 
                85                  90                  95


Gln Leu Glu Leu Ile Lys Pro Phe Cys Glu Asp Leu Asp Gln Trp Leu 
            100                 105                 110


Ser Glu Asp Asp Asn His Val Ala Ala Ile His Cys Lys Ala Gly Lys 
        115                 120                 125


Gly Arg Thr Gly Val Met Ile Cys Ala Tyr Leu Leu His Arg Gly Lys 
    130                 135                 140


Phe Leu Lys Ala Gln Glu Ala Leu Asp Phe Tyr Gly Glu Val Arg Thr 
145                 150                 155                 160


Arg Asp Lys Lys Gly Val Thr Ile Pro Ser Gln Arg Arg Tyr Val Tyr 
                165                 170                 175


Tyr Tyr Ser Tyr Leu Leu Lys Asn His Leu Asp Tyr Arg Pro Val Ala 
            180                 185                 190


Leu Leu Phe His Lys Met Met Phe Glu Thr Ile Pro Met Phe Ser Gly 
        195                 200                 205


Gly Thr Cys Asn Pro Gln Phe Val Val Cys Gln Leu Lys Val Lys Ile 
    210                 215                 220


Tyr Ser Ser Asn Ser Gly Pro Thr Arg Arg Glu Asp Lys Phe Met Tyr 
225                 230                 235                 240


Phe Glu Phe Pro Gln Pro Leu Pro Val Cys Gly Asp Ile Lys Val Glu 
                245                 250                 255


Phe Phe His Lys Gln Asn Lys Met Leu Lys Lys Asp Lys Met Phe His 
            260                 265                 270


Phe Trp Val Asn Thr Phe Phe Ile Pro Gly Pro Glu Glu Thr Ser Glu 
        275                 280                 285


Lys Val Glu Asn Gly Ser Leu Cys Asp Gln Glu Ile Asp Ser Ile Cys 
    290                 295                 300


Ser Ile Glu Arg Ala Asp Asn Asp Lys Glu Tyr Leu Val Leu Thr Leu 
305                 310                 315                 320


Thr Lys Asn Asp Leu Asp Lys Ala Asn Lys Asp Lys Ala Asn Arg Tyr 
                325                 330                 335


Phe Ser Pro Asn Phe Lys Val Lys Leu Tyr Phe Thr Lys Thr Val Glu 
            340                 345                 350


Glu Pro Ser Asn Pro Glu Ala Ser Ser Ser Thr Ser Val Thr Pro Asp 
        355                 360                 365


Val Ser Asp Asn Glu Pro Asp His Tyr Arg Tyr Ser Asp Thr Thr Asp 
    370                 375                 380


Ser Asp Pro Glu Asn Glu Pro Phe Asp Glu Asp Gln His Thr Gln Ile 
385                 390                 395                 400


Thr Lys Val 



<210>  7229
<211>  8725
<212>  DNA
<213>  Homo sapiens

<400>  7229
taccgccccc tgccctgccc tgccctcccc tcgcccggcg cggtcccgtc cgcctctcgc     60

tcgcctcccg cctcccctcg gtcttccgag gcgcccgggc tcccggcgcg gcggcggagg    120

gggcgggcag gccggcgggc ggtgatgtgg cgggactctt tatgcgctgc ggcaggatac    180

gcgctcggcg ctgggacgcg actgcgctca gttctctcct ctcggaagct gcagccatga    240

tggaagtttg agagttgagc cgctgtgagg cgaggccggg ctcaggcgag ggagatgaga    300

gacggcggcg gccgcggccc ggagcccctc tcagcgcctg tgagcagccg cgggggcagc    360

gccctcgggg agccggccgg cctgcggcgg cggcagcggc ggcgtttctc gcctcctctt    420

cgtcttttct aaccgtgcag cctcttcctc ggcttctcct gaaagggaag gtggaagccg    480

tgggctcggg cgggagccgg ctgaggcgcg gcggcggcgg cggcacctcc cgctcctgga    540

gcggggggga gaagcggcgg cggcggcggc cgcggcggct gcagctccag ggagggggtc    600

tgagtcgcct gtcaccattt ccagggctgg gaacgccgga gagttggtct ctccccttct    660

actgcctcca acacggcggc ggcggcggct ggcacatcca gggacccggg ccggttttaa    720

acctcccgtg cgccgccgcc gcaccccccg tggcccgggc tccggaggcc gccggcggag    780

gcagccgttc ggaggattat tcgtcttctc cccattccgc tgccgccgct gccaggcctc    840

tggctgctga ggagaagcag gcccagtcgc tgcaaccatc cagcagccgc cgcagcagcc    900

attacccggc tgcggtccag agccaagcgg cggcagagcg aggggcatca gctaccgcca    960

agtccagagc catttccatc ctgcagaaga agccccgcca ccagcagctt ctgccatctc   1020

tctcctcctt tttcttcagc cacaggctcc cagacatgac agccatcatc aaagagatcg   1080

ttagcagaaa caaaaggaga tatcaagagg atggattcga cttagacttg acctatattt   1140

atccaaacat tattgctatg ggatttcctg cagaaagact tgaaggcgta tacaggaaca   1200

atattgatga tgtagtaagg tttttggatt caaagcataa aaaccattac aagatataca   1260

atctttgtgc tgaaagacat tatgacaccg ccaaatttaa ttgcagagtt gcacaatatc   1320

cttttgaaga ccataaccca ccacagctag aacttatcaa acccttttgt gaagatcttg   1380

accaatggct aagtgaagat gacaatcatg ttgcagcaat tcactgtaaa gctggaaagg   1440

gacgaactgg tgtaatgata tgtgcatatt tattacatcg gggcaaattt ttaaaggcac   1500

aagaggccct agatttctat ggggaagtaa ggaccagaga caaaaaggga gtaactattc   1560

ccagtcagag gcgctatgtg tattattata gctacctgtt aaagaatcat ctggattata   1620

gaccagtggc actgttgttt cacaagatga tgtttgaaac tattccaatg ttcagtggcg   1680

gaacttgcaa tcctcagttt gtggtctgcc agctaaaggt gaagatatat tcctccaatt   1740

caggacccac acgacgggaa gacaagttca tgtactttga gttccctcag ccgttacctg   1800

tgtgtggtga tatcaaagta gagttcttcc acaaacagaa caagatgcta aaaaaggaca   1860

aaatgtttca cttttgggta aatacattct tcataccagg accagaggaa acctcagaaa   1920

aagtagaaaa tggaagtcta tgtgatcaag aaatcgatag catttgcagt atagagcgtg   1980

cagataatga caaggaatat ctagtactta ctttaacaaa aaatgatctt gacaaagcaa   2040

ataaagacaa agccaaccga tacttttctc caaattttaa ggtgaagctg tacttcacaa   2100

aaacagtaga ggagccgtca aatccagagg ctagcagttc aacttctgta acaccagatg   2160

ttagtgacaa tgaacctgat cattatagat attctgacac cactgactct gatccagaga   2220

atgaaccttt tgatgaagat cagcatacac aaattacaaa agtctgaatt tttttttatc   2280

aagagggata aaacaccatg aaaataaact tgaataaact gaaaatggac cttttttttt   2340

ttaatggcaa taggacattg tgtcagatta ccagttatag gaacaattct cttttcctga   2400

ccaatcttgt tttaccctat acatccacag ggttttgaca cttgttgtcc agttgaaaaa   2460

aggttgtgta gctgtgtcat gtatatacct ttttgtgtca aaaggacatt taaaattcaa   2520

ttaggattaa taaagatggc actttcccgt tttattccag ttttataaaa agtggagaca   2580

gactgatgtg tatacgtagg aattttttcc ttttgtgttc tgtcaccaac tgaagtggct   2640

aaagagcttt gtgatatact ggttcacatc ctaccccttt gcacttgtgg caacagataa   2700

gtttgcagtt ggctaagaga ggtttccgaa gggttttgct acattctaat gcatgtattc   2760

gggttagggg aatggaggga atgctcagaa aggaaataat tttatgctgg actctggacc   2820

atataccatc tccagctatt tacacacacc tttctttagc atgctacagt tattaatctg   2880

gacattcgag gaattggccg ctgtcactgc ttgttgtttg cgcatttttt tttaaagcat   2940

attggtgcta gaaaaggcag ctaaaggaag tgaatctgta ttggggtaca ggaatgaacc   3000

ttctgcaaca tcttaagatc cacaaatgaa gggatataaa aataatgtca taggtaagaa   3060

acacagcaac aatgacttaa ccatataaat gtggaggcta tcaacaaaga atgggcttga   3120

aacattataa aaattgacaa tgatttatta aatatgtttt ctcaattgta acgacttctc   3180

catctcctgt gtaatcaagg ccagtgctaa aattcagatg ctgttagtac ctacatcagt   3240

caacaactta cacttatttt actagttttc aatcataata cctgctgtgg atgcttcatg   3300

tgctgcctgc aagcttcttt tttctcatta aatataaaat attttgtaat gctgcacaga   3360

aattttcaat ttgagattct acagtaagcg ttttttttct ttgaagattt atgatgcact   3420

tattcaatag ctgtcagccg ttccaccctt ttgaccttac acattctatt acaatgaatt   3480

ttgcagtttt gcacattttt taaatgtcat taactgttag ggaattttac ttgaatactg   3540

aatacatata atgtttatat taaaaaggac atttgtgtta aaaaggaaat tagagttgca   3600

gtaaactttc aatgctgcac acaaaaaaaa gacatttgat ttttcagtag aaattgtcct   3660

acatgtgctt tattgatttg ctattgaaag aatagggttt tttttttttt tttttttttt   3720

ttttttaaat gtgcagtgtt gaatcatttc ttcatagtgc tcccccgagt tgggactagg   3780

gcttcaattt cacttcttaa aaaaaatcat catatatttg atatgcccag actgcatacg   3840

attttaagcg gagtacaact actattgtaa agctaatgtg aagatattat taaaaaggtt   3900

tttttttcca gaaatttggt gtcttcaaat tataccttca ccttgacatt tgaatatcca   3960

gccattttgt ttcttaatgg tataaaattc cattttcaat aacttattgg tgctgaaatt   4020

gttcactagc tgtggtctga cctagttaat ttacaaatac agattgaata ggacctacta   4080

gagcagcatt tatagagttt gatggcaaat agattaggca gaacttcatc taaaatattc   4140

ttagtaaata atgttgacac gttttccata ccttgtcagt ttcattcaac aatttttaaa   4200

tttttaacaa agctcttagg atttacacat ttatatttaa acattgatat atagagtatt   4260

gattgattgc tcataagtta aattggtaaa gttagagaca actattctaa cacctcacca   4320

ttgaaattta tatgccacct tgtctttcat aaaagctgaa aattgttacc taaaatgaaa   4380

atcaacttca tgttttgaag atagttataa atattgttct ttgttacaat ttcgggcacc   4440

gcatattaaa acgtaacttt attgttccaa tatgtaacat ggagggccag gtcataaata   4500

atgacattat aatgggcttt tgcactgtta ttatttttcc tttggaatgt gaaggtctga   4560

atgagggttt tgattttgaa tgtttcaatg tttttgagaa gccttgctta cattttatgg   4620

tgtagtcatt ggaaatggaa aaatggcatt atatatatta tatatataaa tatatattat   4680

acatactctc cttactttat ttcagttacc atccccatag aatttgacaa gaattgctat   4740

gactgaaagg ttttcgagtc ctaattaaaa ctttatttat ggcagtattc ataattagcc   4800

tgaaatgcat tctgtaggta atctctgagt ttctggaata ttttcttaga ctttttggat   4860

gtgcagcagc ttacatgtct gaagttactt gaaggcatca cttttaagaa agcttacagt   4920

tgggccctgt accatcccaa gtcctttgta gctcctcttg aacatgtttg ccatactttt   4980

aaaagggtag ttgaataaat agcatcacca ttctttgctg tggcacaggt tataaactta   5040

agtggagttt accggcagca tcaaatgttt cagctttaaa aaataaaagt agggtacaag   5100

tttaatgttt agttctagaa attttgtgca atatgttcat aacgatggct gtggttgcca   5160

caaagtgcct cgtttacctt taaatactgt taatgtgtca tgcatgcaga tggaaggggt   5220

ggaactgtgc actaaagtgg gggctttaac tgtagtattt ggcagagttg ccttctacct   5280

gccagttcaa aagttcaacc tgttttcata tagaatatat atactaaaaa atttcagtct   5340

gttaaacagc cttactctga ttcagcctct tcagatactc ttgtgctgtg cagcagtggc   5400

tctgtgtgta aatgctatgc actgaggata cacaaaaata ccaatatgat gtgtacagga   5460

taatgcctca tcccaatcag atgtccattt gttattgtgt ttgttaacaa ccctttatct   5520

cttagtgtta taaactccac ttaaaactga ttaaagtctc attcttgtca ttgtgtgggt   5580

gttttattaa atgagagttt ataattcaaa ttgcttaagt ccattgaagt tttaattaat   5640

gggcagccaa atgtgaatac aaagttttca gttttttttt ttcctgctgt ccttcaaagc   5700

ctactgttta aaaaaaaaaa aaaaaaaaaa catggcctga gagtagagta tctgtctact   5760

catgtttaat taaggaaaaa cacttatttt tagggcttta gtcatcactt cataaattgt   5820

ataagcacat taaatagcgt tctagtcctg aaaaagtcca agattcttag aaaattgtgc   5880

atatttttat tatgacagat gtttgaagat aattccccag aatggatttg atactttaga   5940

tttcaatttt gtggcttttg tctattattc tgtactctgc catcagcata tggaaagctt   6000

catttactca tcatgacttg tgccatataa aaattgatat ttcggaatag tctaaaggac   6060

tttttgtact tgaatttaat catgttgttt ctaatattct taaaagcttg aagactaaag   6120

catatccttt caacaaagca tagtaaggta ataagaaagt gtagtttgta caagtgttaa   6180

aaaaataaag tagacaatgt tacagtggga cttattattt caagtttaca ttttctccat   6240

gtaatttttt aaaaagtaaa tgaaaaaatg tgcaataatg taaaatatga agtgtatgtg   6300

tacacacatt ttatttttcg gtatcttggg tatacgtatg gttgaaaact atactggagt   6360

ctaaaagtat tctaatttat aagaagacat tttggtgatg tttgaaaaat agaaatgtgc   6420

tagttttgtt tttatatcat gtcctttgta cgttgtaata tgagctggct tggttcagta   6480

aatgccatca ccatttccat tgagaattta aaactcacca gtgtttaata tgcaggcttc   6540

caaaggctta tgaaaaaaat caagaccctt aaatctagtt aatttgctgc taacatgaaa   6600

ctctttggtt cttttatttt tgccagataa ttagacacac atctaaagct tagtcttaaa   6660

tggcttaagt gtagctattg attagtgctg ttgctagttc agaaagaaat gtttgtgaat   6720

ggaaacaaga atattcagtc caaactgttg taaggacagt acctgaaaac caggaaacag   6780

gataatggaa aaagtctttt aaagatgaaa tgttggagcc aactttctta tagaattaat   6840

tgtatgtggc tatagaaagc ctaatgattg ttgcttattt ttgagagcat attattcttt   6900

tatgaccata atcttgctgt ttttccatct tccaaaagat cttccttcta atatgtatat   6960

cagaatgtgg gtagccagtc agacaaattc atattggttg gtagctttaa aaagtttgta   7020

atgtgaagac aggaaaggac aaaatagttt gctttggtgg tagtactctg gttgttaagc   7080

taggtatttt gagactactt ccccatcaca acaacaataa aataatcact cataatccta   7140

tcacctggag acatagccat cgttaatatg ttagtgacta tacaatcatg ttttcttctg   7200

tatatccatg tatattcttt aaaaatgaaa tttatactgt acctgatctc aaagcttttt   7260

agcttagtat atctgtcatg aatttgtagg atgttccatt gcatcagaaa acggacagtg   7320

atttgattac tttctaatgc cacagatgca gattacatgt agttattgag aatcctttcg   7380

aattcagtgg cttaatcatg aatgtctaaa tattgttgac attaggatga tacatgtaaa   7440

ttaaagttac atttgtttag catagacaag cttaacattg tagatgtttc tcttcaaaaa   7500

tcatcttaaa catttgcatt tggaattgtg ttaaatagaa tgtgtgaaac actgtattag   7560

taaacttcat cacctttcta cttccttata gtttgaactt ttcagttttt gtagttccca   7620

aacagttgct caatttagag caaattaatt taacacctgc caaaaaaagg ctgctgttgg   7680

cttatcagtt gtctttaaat tcaaatgctc atgtgacttt tatcacatca aaaaatattt   7740

cattaatgat tcacctttag ctctgaaaat taccgcgttt agtaattata gtgggcttat   7800

aaaaacatgc aactcttttt gatagttatt tgagaatttt ggtgaaaaat atttagctga   7860

gggcagtata gaacttataa accaatatat tgatattttt aaaacatttt tacatataag   7920

taaactgcca tctttgagca taactacatt taaaaataaa gctgcatatt tttaaatcaa   7980

gtgtttaaca agaatttata ttttttattt tttaaaatta aaaataattt atatttcctc   8040

tgttgcatga ggattctcat ctgtgcttat aatggttaga gattttattt gtgtggaatg   8100

aagtgaggct tgtagtcatg gttctagtgt ttcagtttgc caagtctgtt tactgcagtg   8160

aaattcatca aatgtttcag tgtggttttc tgtagcctat catttactgg ctattttttt   8220

atgtacacct ttaggatttt ctgcctactc tatccagttg tccaaatgat atcctacatt   8280

ttacaaatgc cctttcagtt tctattttct ttttccatta aattgccctc atgtcctaat   8340

gtgcagtttg taagtgtgtg tgtgtgtgtc tgtgtgtgtg tgaatttgat tttcaagagt   8400

gctagacttc caatttgaga gattaaataa tttaattcag gcaaacattt ttcattggaa   8460

tttcacagtt cattgtaatg aaaatgttaa tcctggatga cctttgacat acagtaatga   8520

atcttggata ttaatgaatt tgttagtagc atcttgatgt gtgttttaat gagttatttt   8580

caaagttgtg cattaaacca aagttggcat actggaagtg tttatatcaa gttccatttg   8640

gctactgatg gacaaaaaat agaaatgcct tcctatggag agtatttttc ctttaaaaaa   8700

ttaaaaaggt taattatttt gacta                                         8725


<210>  7230
<211>  403
<212>  PRT
<213>  Homo sapiens

<400>  7230

Met Thr Ala Ile Ile Lys Glu Ile Val Ser Arg Asn Lys Arg Arg Tyr 
1               5                   10                  15


Gln Glu Asp Gly Phe Asp Leu Asp Leu Thr Tyr Ile Tyr Pro Asn Ile 
            20                  25                  30


Ile Ala Met Gly Phe Pro Ala Glu Arg Leu Glu Gly Val Tyr Arg Asn 
        35                  40                  45


Asn Ile Asp Asp Val Val Arg Phe Leu Asp Ser Lys His Lys Asn His 
    50                  55                  60


Tyr Lys Ile Tyr Asn Leu Cys Ala Glu Arg His Tyr Asp Thr Ala Lys 
65                  70                  75                  80


Phe Asn Cys Arg Val Ala Gln Tyr Pro Phe Glu Asp His Asn Pro Pro 
                85                  90                  95


Gln Leu Glu Leu Ile Lys Pro Phe Cys Glu Asp Leu Asp Gln Trp Leu 
            100                 105                 110


Ser Glu Asp Asp Asn His Val Ala Ala Ile His Cys Lys Ala Gly Lys 
        115                 120                 125


Gly Arg Thr Gly Val Met Ile Cys Ala Tyr Leu Leu His Arg Gly Lys 
    130                 135                 140


Phe Leu Lys Ala Gln Glu Ala Leu Asp Phe Tyr Gly Glu Val Arg Thr 
145                 150                 155                 160


Arg Asp Lys Lys Gly Val Thr Ile Pro Ser Gln Arg Arg Tyr Val Tyr 
                165                 170                 175


Tyr Tyr Ser Tyr Leu Leu Lys Asn His Leu Asp Tyr Arg Pro Val Ala 
            180                 185                 190


Leu Leu Phe His Lys Met Met Phe Glu Thr Ile Pro Met Phe Ser Gly 
        195                 200                 205


Gly Thr Cys Asn Pro Gln Phe Val Val Cys Gln Leu Lys Val Lys Ile 
    210                 215                 220


Tyr Ser Ser Asn Ser Gly Pro Thr Arg Arg Glu Asp Lys Phe Met Tyr 
225                 230                 235                 240


Phe Glu Phe Pro Gln Pro Leu Pro Val Cys Gly Asp Ile Lys Val Glu 
                245                 250                 255


Phe Phe His Lys Gln Asn Lys Met Leu Lys Lys Asp Lys Met Phe His 
            260                 265                 270


Phe Trp Val Asn Thr Phe Phe Ile Pro Gly Pro Glu Glu Thr Ser Glu 
        275                 280                 285


Lys Val Glu Asn Gly Ser Leu Cys Asp Gln Glu Ile Asp Ser Ile Cys 
    290                 295                 300


Ser Ile Glu Arg Ala Asp Asn Asp Lys Glu Tyr Leu Val Leu Thr Leu 
305                 310                 315                 320


Thr Lys Asn Asp Leu Asp Lys Ala Asn Lys Asp Lys Ala Asn Arg Tyr 
                325                 330                 335


Phe Ser Pro Asn Phe Lys Val Lys Leu Tyr Phe Thr Lys Thr Val Glu 
            340                 345                 350


Glu Pro Ser Asn Pro Glu Ala Ser Ser Ser Thr Ser Val Thr Pro Asp 
        355                 360                 365


Val Ser Asp Asn Glu Pro Asp His Tyr Arg Tyr Ser Asp Thr Thr Asp 
    370                 375                 380


Ser Asp Pro Glu Asn Glu Pro Phe Asp Glu Asp Gln His Thr Gln Ile 
385                 390                 395                 400


Thr Lys Val 



<210>  7231
<211>  546
<212>  DNA
<213>  Homo sapiens

<400>  7231
gccttatgtc tttctgcata attatagagt agccaaaacc tgttttaggt taatcacctc     60

tggcaaaata aatgataaaa gcatagcttt tgtaagcaga atgatattac agaagttaac    120

ttataaatct aagtgtatta aagacactta ggaaatttat gataatgctg ggtcagcatt    180

acagttttaa ctttttacag tttttcatat gctttttttg tgattttgct gtagaaaatt    240

aacagttggc atttggctta gttcaagtat aatgctgttg acaagtatat ctgacacgtc    300

attgaactaa taatattttt gaaagctgat aggtacttat ttttaaagct atagaggtaa    360

tatttcatca gttgcagatt tgttgccaaa tgaacgagtt tgtagtattg ctaacaagga    420

gaagaattac tagcaagtct tgatgttact tttgaagagt gtgatgattg catttaggaa    480

gatatctaaa cttctgtttc aaagcaaaaa gtatgtgcaa atttcttact catgacaaat    540

tcatat                                                               546


<210>  7232
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  7232

Met Leu Leu Leu Lys Ser Val Met Ile Ala Phe Arg Lys Ile Ser Lys 
1               5                   10                  15


Leu Leu Phe Gln Ser Lys Lys Tyr Val Gln Ile Ser Tyr Ser 
            20                  25                  30


<210>  7233
<211>  1019
<212>  DNA
<213>  Homo sapiens

<400>  7233
gcagagaagt cagacaactg atagttatta taaagaaaaa tgttctgaga gtgaggtaac     60

cgcttaaggg aaggaagcct ccttctgtct tattcactaa tttacaagaa gataattgtg    120

ttacacttcc ttaggagtca ttcatttgta tatttgacac ttttgcttta tgaacatgtg    180

aagattattc aaaagtaagc tgttggtgat ttttttcttc caagaaagca tgccacaggg    240

caacttctag ggttggttct catctagtcc tgtgctccac actatctgca tctgcactta    300

agtttcaata ttagataact cacatgttta aactatgaag aaagagttaa aacatcctga    360

gaatgctagt aagtatgtat ttttgaaagg acttccaaaa tttgagttta aagaggtaaa    420

ctccttttac atgacaaagt tacttagaaa cactactgct gtttccctct cccttgcctt    480

ctccctgtcc catgcatacc cccagctgtg ttccagaatg atggcacata aagtaaacat    540

tcatatttat ttccctgtaa ataattttcc tcaaaattaa agtggaaaag gagagttact    600

actagtagaa agtagaactg tacccttggg caggggtgtg tgtgtgtagt taaagatcaa    660

tttaacttaa aaggtcttgg ttagagaata aaaactggcc cttattagct ttaatttaca    720

tgaaaaatga aaaattttag gccaggcaca gtggctcagg cctgtaatcc cttaactttg    780

ggagaccaag gggagtggat cacttgaggt caggagttca agacagcctg gccaacatgc    840

tgactcaccc ttccctactg aaaatacaaa agttagccag gcgcagtggc catccctaca    900

gtgctagcta ctcgggaggc tgaggcagga gaattgcttg aacccgggag gcaaggttgc    960

ggtgagctga gatcgcacca ctgcactcca gactgggtga cagagcgaga ctccatctc    1019


<210>  7234
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  7234

Met Lys Lys Glu Leu Lys His Pro Glu Asn Ala Ser Lys Tyr Val Phe 
1               5                   10                  15


Leu Lys Gly Leu Pro Lys Phe Glu Phe Lys Glu Val Asn Ser Phe Tyr 
            20                  25                  30


Met Thr Lys Leu Leu Arg Asn Thr Thr Ala Val Ser Leu Ser Leu Ala 
        35                  40                  45


Phe Ser Leu Ser His Ala Tyr Pro Gln Leu Cys Ser Arg Met Met Ala 
    50                  55                  60


His Lys Val Asn Ile His Ile Tyr Phe Pro Val Asn Asn Phe Pro Gln 
65                  70                  75                  80


Asn 



<210>  7235
<211>  380
<212>  DNA
<213>  Homo sapiens

<400>  7235
caattatttc aagatcatct tctaagtgtt cactaaaatg gatgacatac atttcagaga     60

agaatttttt gtttgtggaa cgaatgcatg aatgaggaca aggagaggcc tggatcacaa    120

ctttgtactg gaatatcagg agttgtgtaa agcaaggaag cggagactct gcagaacaaa    180

gccccttcaa gacaaggaaa tgccatttgg agtagctact ttgaggacaa gagacaaaaa    240

gcctgaggag aaagtcacca tgaaggaaac agaaagatta aacagcatgc gtgatctttg    300

attcagagtc cccatctcac cctggactgc cttcctttgg aattcccttg tggaaaaaaa    360

aattaaactc ttatttggtt                                                380


<210>  7236
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  7236

Met Arg Thr Arg Arg Gly Leu Asp His Asn Phe Val Leu Glu Tyr Gln 
1               5                   10                  15


Glu Leu Cys Lys Ala Arg Lys Arg Arg Leu Cys Arg Thr Lys Pro Leu 
            20                  25                  30


Gln Asp Lys Glu Met Pro Phe Gly Val Ala Thr Leu Arg Thr Arg Asp 
        35                  40                  45


Lys Lys Pro Glu Glu Lys Val Thr Met Lys Glu Thr Glu Arg Leu Asn 
    50                  55                  60


Ser Met Arg Asp Leu 
65


<210>  7237
<211>  556
<212>  DNA
<213>  Homo sapiens

<400>  7237
gtgactctgg acagtgaaca ttggtggaaa ttggttatcc ccaatttcca gctcacggca     60

ttggaagaca tcataaacat taatggagag cgggatgcca gaataagttg atccaaatga    120

tgcaggaata tttagcagca aggagaaagg aattcacatt tctcagtacc cactatgtgc    180

catactttgt gataagatgg tttccctcca atatatcctc attgtcagca atgtcgggaa    240

acaggaatca tttccccttc tacaggtgat aaaactgaag caagaaacat acaggctaac    300

atcagctgag ctgagatttg aactccactc tttttgaccc tggagctgat gaatgctgct    360

tctagaggtt gagtatccct tatccgaaat ccttggaacc aggagatttt tggatttggg    420

aatatttgca tatacataat gagatatctt ggagatggga cccaagtcta aatacaaaat    480

tattttgttg tatatacacc ttgtacacat agactgaaga taattttata caatatttta    540

aataattttg tgcgtg                                                    556


<210>  7238
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  7238

Met Met Gln Glu Tyr Leu Ala Ala Arg Arg Lys Glu Phe Thr Phe Leu 
1               5                   10                  15


Ser Thr His Tyr Val Pro Tyr Phe Val Ile Arg Trp Phe Pro Ser Asn 
            20                  25                  30


Ile Ser Ser Leu Ser Ala Met Ser Gly Asn Arg Asn His Phe Pro Phe 
        35                  40                  45


Tyr Arg 
    50


<210>  7239
<211>  551
<212>  DNA
<213>  Homo sapiens

<400>  7239
gatgccaaga gcctggtttg aatacaagcc ttgccattgt gtgactctgc catcaccatg     60

agccaaacat cccccaagta gcccactggt cccaggacaa ggagggagac atgaagcaga    120

gctcatccag ctgctgcagc cccacttgac ccagagacct acactgggaa gcagagctgc    180

ccagtcaagt ccaacctgga tgtgtggaac cccagccaac ctgatgcatg agcactcacg    240

gcattggaag acatcataaa cattaatgga gagcgggatg ccagaataag ttgatccaaa    300

tgatgcagga atatttagca gcaaggagaa aggaattcac atttctcagt acccactatg    360

tgccatactt tgtgataaga tggtttccct ccaatatatc ctcattgtca gcaatgtcgg    420

gaaacaggaa tcatttcccc ttctacaggt gataaaactg aagcaagaaa catacaggct    480

aacatcagct gagctgagat ttgaactcca ctctttttga ccctggagct gatgaatgct    540

gcttctagag g                                                         551


<210>  7240
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  7240

Met Met Gln Glu Tyr Leu Ala Ala Arg Arg Lys Glu Phe Thr Phe Leu 
1               5                   10                  15


Ser Thr His Tyr Val Pro Tyr Phe Val Ile Arg Trp Phe Pro Ser Asn 
            20                  25                  30


Ile Ser Ser Leu Ser Ala Met Ser Gly Asn Arg Asn His Phe Pro Phe 
        35                  40                  45


Tyr Arg 
    50


<210>  7241
<211>  1484
<212>  DNA
<213>  Homo sapiens

<400>  7241
gggcgggcgg gccggagcag caattgccac ttccccagct tcctccctgg tctggggcgc     60

ctctggccgc ccgggacggc gccttcccac agccggaagt cagtcccgct ggccccgcgc    120

cgccttcgca ctgtccccca aggccacggc tgcccccgcc ctccccgggg ctttttgttt    180

tttacgccag ccccatttat cacttccaac ctgcctatcg cccggcacca actgttgcaa    240

gttccgtaat aactgctgct atgaacttct ccgtcgaaac tgctcctccc cagagcctgt    300

ttaagaagca gaaataagaa taaattcccg gatgccggtg gatgcactga cctctaagat    360

tttcaaaggt gaagtggata cacgttatta agtcattggg agacatcgcc aacattggga    420

aacctagtaa aaagtggaaa tcgagcgttt taaataaaaa aaaaaaaagg tttctactag    480

caagactgat cgtaggcgaa cttctcaagg aattttggaa tattgtgcca aagtgagaat    540

atttaatatt tccaaaagta gacttaacta ggaatactta aagcagagac tattggaaat    600

gctttaattt gggatttcag gaaagggctt gaagagaaat attttatatg agcaagcctc    660

ttggaataat tgaatcacct taattttgtc actgttactt cgaagagaac gagaagagag    720

aagatgggaa acgaaaggag aaagggaaaa gaaatggggt ggaaagaaaa aagcagaaga    780

gatcgcccta taccagtagg cctagtaccc taggattctg gcctctttct cccacctttg    840

gtgtttaaga ttaaggacag tgcattcctg cttttagaaa tttaaattta agtttgaaga    900

cttaatttta attactgtag taggtaaagc aaagtcgtta aatacttgac atcaggatcc    960

cattggagta ttgatttagg tcttttcaaa ggtggtggtc ctggttctct gcaccagcca   1020

ctggcggaat ggcggaatgg tgtatctacc aatgaacaga tggactgggt gggcctcggg   1080

tacgggtggc ttgagatgca aatgcaaggg taggaaggca ccttcccccc caccactccc   1140

agcccacccc gccaatctta aaacattgat ctttataaaa ttcgcaaacg tcccacagga   1200

tttcattggc ttaagagtat tgtcaaatga agacgccagg aagtattgag tttctgggta   1260

cataatactg tcctgagtgt tgaaggaaga ggactaatac gagattttaa aaaatggctg   1320

tggacaacca tccttcaggt gtgatggcag gacatcttgt atcacctgaa acttcctttt   1380

ttcgccgcta ggtggtgggt gtgagtcttt tgcggccttt aagtttctac ggtgtttgga   1440

ggaaatacgt ttcagtttca aataaatgaa caacgtgtaa ctct                    1484


<210>  7242
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7242

Met Val Tyr Leu Pro Met Asn Arg Trp Thr Gly Trp Ala Ser Gly Thr 
1               5                   10                  15


Gly Gly Leu Arg Cys Lys Cys Lys Gly Arg Lys Ala Pro Ser Pro Pro 
            20                  25                  30


Pro Leu Pro Ala His Pro Ala Asn Leu Lys Thr Leu Ile Phe Ile Lys 
        35                  40                  45


Phe Ala Asn Val Pro Gln Asp Phe Ile Gly Leu Arg Val Leu Ser Asn 
    50                  55                  60


Glu Asp Ala Arg Lys Tyr 
65                  70


<210>  7243
<211>  4903
<212>  DNA
<213>  Homo sapiens

<400>  7243
gggccgggcg ggcggcagaa gatggcgagg gtgtgtaggc ggcagcaatg ctccgttgag     60

agacgcggct ttcggcaaga actggattcg tggcgccaca agctcattca ctgtgtaggt    120

cccgtttccc tctgtgcggc ggccggcggg accataaggg cttaactcat atatttaacc    180

cccctccaaa aaggtttgaa agtattcttg aagggctgtt tggacctgca ttattaaaag    240

atctcagttt atttaaagac tgtgaacctg aaagcatttc tgattggact tttgatgaaa    300

actgtttatt ctgttgcttg agaagagata aagtaaaggg acacttagtc ggtctggatg    360

aaccagcttc gggagctggg caagaagctc tgcttaaaca agagcaagca aaaatcattc    420

gattcgagag acaagcagaa gaattcctca atgcagtctt ttatagaaaa gacagtccct    480

gggtctccga ccccaatatt cccctagtgg cccgtgagat catgcagcga atgatccaac    540

aatttgctgc tgaatatacc tcaaaaaata gctctactca ggaccccagc cagcccaata    600

gcacaaagaa ccaaagcctg ccgaaagcat ctccagtcac cacctctccc acggctgcaa    660

ctactcagaa ccctgtgctc agcaaacttc tcatggctga ccaagactca cctctggacc    720

ttactgtcag aaagtctcag tcagaaccta gcgaacaaga cggtgtactt gatctgtcca    780

ctaagaaaag tccatgtgct ggcagcactt ccctgagcca ctctccaggc tgctccagta    840

ctcaagggaa cgggcgacct gggagaccca gccagtaccg cccagacgga cttcggagtg    900

gtgatggggt acctccaaga agcttacagg atggaaccag ggaaggtttt ggacactcca    960

catcactcaa agttccactg gctcgatccc tgcagattag tgaagaacta ctgagcagaa   1020

accaattgtc cacagctgcc agccttgggc catctggatt acagaatcat ggacaacact   1080

taatattatc cagggaagcc tcttgggcaa aaccacatta cgagttcaac ctcagccgta   1140

tgaagttcag gggaaatggt gcactcagca acatcagtga ccttcctttt cttgcagaaa   1200

actctgcctt tccaaaaatg gcacttcaag caaaacaaga tggaaaaaag gatgtgagcc   1260

attcatctcc tgtagattta aagataccac aagttcgagg aatggatctt tcttgggagt   1320

ctcgcactgg tgatcagtac agctatagct ctttggtaat gggttcacaa acggagagcg   1380

cgcttagtaa aaaattaagg gctattcttc caaaacaaag tagaaaaagc atgttagatg   1440

ctggacccga ttcttggggc tcagatgctg agcagtctac ctctggacag ccatatccca   1500

catcggatca agaaggagac cctggctcca agcagcctcg gaagaaaaga gggcgttaca   1560

gacagtacaa cagtgagata ctggaggaag caatctcagt ggttatgagt ggaaaaatga   1620

gtgtttccaa agctcagagt atttatggga ttccccacag tacactggag tacaaagtaa   1680

aggagaggct gggcactttg aaaaaccctc caaagaaaaa gatgaaatta atgaggtcgg   1740

aggggccaga tgtttctgta aagattgaat tagatcccca gggagaggca gcacaaagtg   1800

caaatgaatc aaaaaacgag taggaatact gtagagtgcc aattactgta caaactgggt   1860

gagcactact gcatcattgt tcagctatca ttgcttgcac gtaatttcat ttactgtgac   1920

acttgcttct ttgcagattt tgcattgact tgtgtgtaca gagatgaaat gtgcattctg   1980

aatgttgcat attttaaatt tttcatgtgc agtatggctc ggaatatgtt tggccttttg   2040

catgtttctc tacaaaagag aattgagtta cctcacagag aacagataca tggaagtgga   2100

ctccttgcct gtagagcctg catgcttttt tgtttttttt tgttgttgtt gttttttctt   2160

aagttatatt tgtttttact ttttaaaaaa gaagaggaaa caaagccccc ttttagaaac   2220

tacgtctgtc atactgggag ctttatcact gcaaattgga aagccatctt atacaaaatt   2280

attcacattt ttcatctacg attcaactaa tcgaaggatt aaactaaaga aaaaactaag   2340

aagaacaatg aacctttgac tttgagaaat ttggttattc actgacataa ttattgggtc   2400

atttatagtt acattttata attttcttct cactattaaa tttatttaaa ttagcaagct   2460

attagtgctc acccagaggg gaaggtggtg gaaaatgtgc acacactacc ttcagaaatg   2520

cttcagttaa ttactttgaa cactaccttt gctgtaattt catttgagat tttctaaggg   2580

tagaatttgg tctcaccaac aagtgaggat atagccttat ctcatggagg acgagctccg   2640

tatttactca ggagcagtca gggtacatta cataaaacaa tggaggatgc ctcattttag   2700

caaactaggt ttctttgtat tcttcagtcc ttttacagaa ttgatgtgct aactgaatat   2760

cattgcagca actagactaa gatattcaag atctctttat tggggatggg agaaataggg   2820

aaagaaatgt gtataagtaa ttatgatatt gcaaaagtga tacttagatt ttacagcctc   2880

agtagtctgc ccagtgtcca cattaatgaa ggatccatgt ttgtagtgag agaaaaaaac   2940

cccaaggtaa cccgatatga tttaggatgc atatcagttc taacaattca atcagaagtc   3000

aagctcattg gaattccttt tttaactgat ccaaatacta gtagaagggg gagggagagg   3060

tgttgggttt tttttttaag tttttattta attttgttgg ttagaatttt tttctgtttt   3120

tggcatccta cataataccc cccttcttga ctttttctga taattagctg atattcatgg   3180

ttgtttagca cacagttcag gacctttgag atcatgtttg tataagcact ccttgaagaa   3240

tatctaagct ttttctgaga tgggctttta aaattataat aagggaagtt tattttctgc   3300

ggtttttgca agaataagca aagcccatgg aatttaattt ttcattgtga tcagattaaa   3360

attactattt gtgcaaaaca aattccacac cacatgtact gtatattcta atctgctgag   3420

aaaggtggtc aggcccttct aaatgcttaa ccaaaaacaa acattattgg agtttcagtg   3480

taaaataaaa ttaaaattgg agggttggtt agattgattt cagatggata ctaacagttt   3540

gaggggaggt ccagatattt ccaaggcata aattcttgcc tggaaacttt ggagcaatta   3600

attaaattag gttaagtttt ccctcagcaa cctgtgtgtt caaaggttag gcacaccatt   3660

gctgttacta aaatacatgc actgctcatt cttgacatag cttgggtgtg ggttcctctt   3720

gttttggtta ttttgtgtag cagtttaatc agtggataac tgagcctgtt tcctcttagc   3780

tttctagact tcttaacaga aaaaacagtt tgggttcaat agcattttat gattctacaa   3840

tattttgtca cctagctgga agttgcaata aaaattcctt atgaaatata tggttttcat   3900

ctgtaattga aggaaatcat agaaagtttg ctgaaagcaa agggctaagc ttatgaagga   3960

atgcctcctt tgttacacac tcaagaattt gtcagcacac aattaattgc agccatagta   4020

cctttttgcg taatgtttgg gatattcagt agcccaggat tgctacaaaa aggtcctttg   4080

agaaaattaa tttgtgcttg cttttatccc ctctcagaaa gacatcacta aaggcccatt   4140

aaaaatctgg ccctaaaagt tcaacttttg tagagtttat tgttcagaga ggtttaatcc   4200

tatgtggtag tctatataag tgatgtatga gttgagttat gtaaattttg tcattgtagt   4260

gtacatggag tgatcatttt actaacataa atattttcta tgtgtgtttc agtggatgac   4320

aatcgagcag cagaagaatg gtgtgcctac cctttaatgc tgcagtttaa gagaacttgt   4380

attgtgtcat ttcagattgt aggctgagag ttgtaaatag tgaaaatttg agtacttcta   4440

ttatttgttt tggttagaaa gtgaatttaa aaaacaaacc aaactctaaa ctttctcaga   4500

ttaaaagtcc tgagacctga agattgtaat attcatgtct gtgaagcttt taaacattac   4560

acttgagatc agtcatgact tgatattcag gtaaattttc ttttccaaga agcttttgaa   4620

taagcatatt tcctccaaag gtctctctct ttctctctct ttttttgagt gtagattatt   4680

ttaaagcact aattgcatta cattggtaac tgcaatataa aatagccatt attgttttgt   4740

gaagcatggt tgaaattagc tagtggtccc ttttgaattt catgagcctc tcaaaaaaga   4800

aaaacttaaa aaaaaaaaaa aaaaaaaaca aaaagctgct ggaatatttc aaaagatata   4860

tattttacct tattataggt tttgtaaagt tagtttgtaa tat                     4903


<210>  7244
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  7244

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400


Met Lys Leu Met Arg Ser Glu Gly Pro Asp Val Ser Val Lys Ile Glu 
                405                 410                 415


Leu Asp Pro Gln Gly Glu Ala Ala Gln Ser Ala Asn Glu Ser Lys Asn 
            420                 425                 430


Glu 



<210>  7245
<211>  2318
<212>  DNA
<213>  Homo sapiens

<400>  7245
cgggcggcag aagatggcga gggtgtgtag gcggcagcaa tgctccgttg agagacgcgg     60

ctttcggcaa gaactggatt cgtggcgcca caagctcatt cactgtgtag gtcccgtttc    120

cctctgtgcg gcggccggcg ggaccataag ggcttaactc atatatttaa cccccctcca    180

aaaaggtttg aaagtattct tgaagggctg tttggacctg cattattaaa agatctcagt    240

ttatttaaag actgtgaacc tgaaagcatt tctgattgga cttttgatga aaactgttta    300

ttctgttgct tgagaagaga taaagtaaag ggacacttag tcggtctgga tgaaccagct    360

tcgggagctg ggcaagaagc tctgcttaaa caagagcaag caaaaatcat tcgattcgag    420

agacaagcag aagaattcct caatgcagtc ttttatagaa aagacagtcc ctgggtctcc    480

gaccccaata ttcccctagt ggcccgtgag atcatgcagc gaatgatcca acaatttgct    540

gctgaatata cctcaaaaaa tagctctact caggacccca gccagcccaa tagcacaaag    600

aaccaaagcc tgccgaaagc atctccagtc accacctctc ccacggctgc aactactcag    660

aaccctgtgc tcagcaaact tctcatggct gaccaagact cacctctgga ccttactgtc    720

agaaagtctc agtcagaacc tagcgaacaa gacggtgtac ttgatctgtc cactaagaaa    780

agtccatgtg ctggcagcac ttccctgagc cactctccag gctgctccag tactcaaggg    840

aacgggcgac ctgggagacc cagccagtac cgcccagacg gacttcggag tggtgatggg    900

gtacctccaa gaagcttaca ggatggaacc agggaaggtt ttggacactc cacatcactc    960

aaagttccac tggctcgatc cctgcagatt agtgaagaac tactgagcag aaaccaattg   1020

tccacagctg ccagccttgg gccatctgga ttacagaatc atggacaaca cttaatatta   1080

tccagggaag cctcttgggc aaaaccacat tacgagttca acctcagccg tatgaagttc   1140

aggggaaatg gtgcactcag caacatcagt gaccttcctt ttcttgcaga aaactctgcc   1200

tttccaaaaa tggcacttca agcaaaacaa gatggaaaaa aggatgtgag ccattcatct   1260

cctgtagatt taaagatacc acaagttcga ggaatggatc tttcttggga gtctcgcact   1320

ggtgatcagt acagctatag ctctttggta atgggttcac aaacggagag cgcgcttagt   1380

aaaaaattaa gggctattct tccaaaacaa agtagaaaaa gcatgttaga tgctggaccc   1440

gattcttggg gctcagatgc tgagcagtct acctctggac agccatatcc cacatcggat   1500

caagaaggag accctggctc caagcagcct cggaagaaaa gagggcgtta cagacagtac   1560

aacagtgaga tactggagga agcaatctca gtggttatga gtggaaaaat gagtgtttcc   1620

aaagctcaga gtatttatgg gattccccac agtacactgg agtacaaagt aaaggagagg   1680

ctgggcactt tgaaaaaccc tccaaagaaa aagatgaaat taatgagtgg atgacaatcg   1740

agcagcagaa gaatggtgtg cctacccttt aatgctgcag tttaagagaa cttgtattgt   1800

gtcatttcag attgtaggct gagagttgta aatagtgaaa atttgagtac ttctattatt   1860

tgttttggtt agaaagtgaa tttaaaaaac aaaccaaact ctaaactttc tcagattaaa   1920

agtcctgaga cctgaagatt gtaatattca tgtctgtgaa gcttttaaac attacacttg   1980

agatcagtca tgacttgata ttcaggtaaa ttttcttttc caagaagctt ttgaataagc   2040

atatttcctc caaaggtctc tctctttctc tctctttttt tgagtgtaga ttattttaaa   2100

gcactaattg cattacattg gtaactgcaa tataaaatag ccattattgt tttgtgaagc   2160

atggttgaaa ttagctagtg gtcccttttg aatttcatga gcctctcaaa aaagaaaaac   2220

ttaaaaaaaa aaaaaaaaaa aaacaaaaag ctgctggaat atttcaaaag atatatattt   2280

taccttatta taggttttgt aaagttagtt tgtaatat                           2318


<210>  7246
<211>  406
<212>  PRT
<213>  Homo sapiens

<400>  7246

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400


Met Lys Leu Met Ser Gly 
                405


<210>  7247
<211>  1136
<212>  DNA
<213>  Homo sapiens

<400>  7247
tcgtggcgcc acaagctcat tcactgtgta ggtcccgttt ccctctgtgc ggcggccggc     60

gggaccataa gggcttaact catatattta acccccctcc aaaaaagcat gttactctga    120

ggtttctgaa gcaccagcaa atggattaag taaaggtctg gggattttcg acagacaaat    180

tggtaaaagt tggaggtggc cagcaggcag aaaaagaaga cctttagatt ggcataagca    240

aggggttcac tttgtccagc aagactgtca tcctttctct gtacctcgga agagaagaac    300

ttcctttgcc agtgtttgga tatcccccct ccccagtcaa tcctttctgc acctgggggt    360

gcagtgtctc taggacagca cttctcaaac ttcagtaaac ataagaatca cctggaaagc    420

ttgttaaaac taagattctt gaataccatt tccagatatt ctgattgatt aggtctgggt    480

tgaggtataa gaatttacat ttctgtggaa caagctgccc gatgctgata ttgcaggtca    540

gtggaccaca cttttgagta aggtctaggg tcttagcctt tatgcgagag tctcagtttc    600

atttcttaag gcccttctgc ccctgcatat gtattaaaac ccaagttggt tttaatacat    660

gggtaacaca gcatgttacc catattaatc agtgcactct cagctctgtc ctccagattc    720

ttcatttctg gtacgtgagg catttcctac ctaccttttc agcttagctt gatgtgtgtg    780

tttgttgggg aggggagtgg gtatacgtgt gcacttatca catattttat ccattatata    840

tagtaataag acttttaagt tgtcttcaca tacttctctg aatagtttgg tcccaccaat    900

aaacctatca ctgttcaact ggaagtttcc tgtaaatcta tttatagacc ttttgggaaa    960

atgccattaa ataaatacca cattattttg gctttagtat atacttaatt tacggaaatg   1020

cagtgcttta cagttattta gaacatcact tctcatttga aaatagtaaa gttttcagat   1080

ttgtacccaa tgtgttttga gcttagaatg taacaatgca tgtttttaaa aattgc       1136


<210>  7248
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  7248

Met Arg Glu Ser Gln Phe His Phe Leu Arg Pro Phe Cys Pro Cys Ile 
1               5                   10                  15


Cys Ile Lys Thr Gln Val Gly Phe Asn Thr Trp Val Thr Gln His Val 
            20                  25                  30


Thr His Ile Asn Gln Cys Thr Leu Ser Ser Val Leu Gln Ile Leu His 
        35                  40                  45


Phe Trp Tyr Val Arg His Phe Leu Pro Thr Phe Ser Ala 
    50                  55                  60


<210>  7249
<211>  4945
<212>  DNA
<213>  Homo sapiens

<400>  7249
gtgcgaagcg tgaggtggag atgggggcgg agggagctgg agctgtcaca gtccccgggt     60

gcgcctgacc gagccaagtg gggtgtcatg gccgcggggg gcagcggctg cacttcctca    120

gcgggcggcg gtggccgggg agttaatcct cgacgcacgg gtcccgtttc cctctgtgcg    180

gcggccggcg ggaccataag ggcttaactc atatatttaa cccccctcca aaaaggtttg    240

aaagtattct tgaagggctg tttggacctg cattattaaa agatctcagt ttatttaaag    300

actgtgaacc tgaaagcatt tctgattgga cttttgatga aaactgttta ttctgttgct    360

tgagaagaga taaagtaaag ggacacttag tcggtctgga tgaaccagct tcgggagctg    420

ggcaagaagc tctgcttaaa caagagcaag caaaaatcat tcgattcgag agacaagcag    480

aagaattcct caatgcagtc ttttatagaa aagacagtcc ctgggtctcc gaccccaata    540

ttcccctagt ggcccgtgag atcatgcagc gaatgatcca acaatttgct gctgaatata    600

cctcaaaaaa tagctctact caggacccca gccagcccaa tagcacaaag aaccaaagcc    660

tgccgaaagc atctccagtc accacctctc ccacggctgc aactactcag aaccctgtgc    720

tcagcaaact tctcatggct gaccaagact cacctctgga ccttactgtc agaaagtctc    780

agtcagaacc tagcgaacaa gacggtgtac ttgatctgtc cactaagaaa agtccatgtg    840

ctggcagcac ttccctgagc cactctccag gctgctccag tactcaaggg aacgggcgac    900

ctgggagacc cagccagtac cgcccagacg gacttcggag tggtgatggg gtacctccaa    960

gaagcttaca ggatggaacc agggaaggtt ttggacactc cacatcactc aaagttccac   1020

tggctcgatc cctgcagatt agtgaagaac tactgagcag aaaccaattg tccacagctg   1080

ccagccttgg gccatctgga ttacagaatc atggacaaca cttaatatta tccagggaag   1140

cctcttgggc aaaaccacat tacgagttca acctcagccg tatgaagttc aggggaaatg   1200

gtgcactcag caacatcagt gaccttcctt ttcttgcaga aaactctgcc tttccaaaaa   1260

tggcacttca agcaaaacaa gatggaaaaa aggatgtgag ccattcatct cctgtagatt   1320

taaagatacc acaagttcga ggaatggatc tttcttggga gtctcgcact ggtgatcagt   1380

acagctatag ctctttggta atgggttcac aaacggagag cgcgcttagt aaaaaattaa   1440

gggctattct tccaaaacaa agtagaaaaa gcatgttaga tgctggaccc gattcttggg   1500

gctcagatgc tgagcagtct acctctggac agccatatcc cacatcggat caagaaggag   1560

accctggctc caagcagcct cggaagaaaa gagggcgtta cagacagtac aacagtgaga   1620

tactggagga agcaatctca gtggttatga gtggaaaaat gagtgtttcc aaagctcaga   1680

gtatttatgg gattccccac agtacactgg agtacaaagt aaaggagagg ctgggcactt   1740

tgaaaaaccc tccaaagaaa aagatgaaat taatgaggtc ggaggggcca gatgtttctg   1800

taaagattga attagatccc cagggagagg cagcacaaag tgcaaatgaa tcaaaaaacg   1860

agtaggaata ctgtagagtg ccaattactg tacaaactgg gtgagcacta ctgcatcatt   1920

gttcagctat cattgcttgc acgtaatttc atttactgtg acacttgctt ctttgcagat   1980

tttgcattga cttgtgtgta cagagatgaa atgtgcattc tgaatgttgc atattttaaa   2040

tttttcatgt gcagtatggc tcggaatatg tttggccttt tgcatgtttc tctacaaaag   2100

agaattgagt tacctcacag agaacagata catggaagtg gactccttgc ctgtagagcc   2160

tgcatgcttt tttgtttttt tttgttgttg ttgttttttc ttaagttata tttgttttta   2220

ctttttaaaa aagaagagga aacaaagccc ccttttagaa actacgtctg tcatactggg   2280

agctttatca ctgcaaattg gaaagccatc ttatacaaaa ttattcacat ttttcatcta   2340

cgattcaact aatcgaagga ttaaactaaa gaaaaaacta agaagaacaa tgaacctttg   2400

actttgagaa atttggttat tcactgacat aattattggg tcatttatag ttacatttta   2460

taattttctt ctcactatta aatttattta aattagcaag ctattagtgc tcacccagag   2520

gggaaggtgg tggaaaatgt gcacacacta ccttcagaaa tgcttcagtt aattactttg   2580

aacactacct ttgctgtaat ttcatttgag attttctaag ggtagaattt ggtctcacca   2640

acaagtgagg atatagcctt atctcatgga ggacgagctc cgtatttact caggagcagt   2700

cagggtacat tacataaaac aatggaggat gcctcatttt agcaaactag gtttctttgt   2760

attcttcagt ccttttacag aattgatgtg ctaactgaat atcattgcag caactagact   2820

aagatattca agatctcttt attggggatg ggagaaatag ggaaagaaat gtgtataagt   2880

aattatgata ttgcaaaagt gatacttaga ttttacagcc tcagtagtct gcccagtgtc   2940

cacattaatg aaggatccat gtttgtagtg agagaaaaaa accccaaggt aacccgatat   3000

gatttaggat gcatatcagt tctaacaatt caatcagaag tcaagctcat tggaattcct   3060

tttttaactg atccaaatac tagtagaagg gggagggaga ggtgttgggt ttttttttta   3120

agtttttatt taattttgtt ggttagaatt tttttctgtt tttggcatcc tacataatac   3180

cccccttctt gactttttct gataattagc tgatattcat ggttgtttag cacacagttc   3240

aggacctttg agatcatgtt tgtataagca ctccttgaag aatatctaag ctttttctga   3300

gatgggcttt taaaattata ataagggaag tttattttct gcggtttttg caagaataag   3360

caaagcccat ggaatttaat ttttcattgt gatcagatta aaattactat ttgtgcaaaa   3420

caaattccac accacatgta ctgtatattc taatctgctg agaaaggtgg tcaggccctt   3480

ctaaatgctt aaccaaaaac aaacattatt ggagtttcag tgtaaaataa aattaaaatt   3540

ggagggttgg ttagattgat ttcagatgga tactaacagt ttgaggggag gtccagatat   3600

ttccaaggca taaattcttg cctggaaact ttggagcaat taattaaatt aggttaagtt   3660

ttccctcagc aacctgtgtg ttcaaaggtt aggcacacca ttgctgttac taaaatacat   3720

gcactgctca ttcttgacat agcttgggtg tgggttcctc ttgttttggt tattttgtgt   3780

agcagtttaa tcagtggata actgagcctg tttcctctta gctttctaga cttcttaaca   3840

gaaaaaacag tttgggttca atagcatttt atgattctac aatattttgt cacctagctg   3900

gaagttgcaa taaaaattcc ttatgaaata tatggttttc atctgtaatt gaaggaaatc   3960

atagaaagtt tgctgaaagc aaagggctaa gcttatgaag gaatgcctcc tttgttacac   4020

actcaagaat ttgtcagcac acaattaatt gcagccatag tacctttttg cgtaatgttt   4080

gggatattca gtagcccagg attgctacaa aaaggtcctt tgagaaaatt aatttgtgct   4140

tgcttttatc ccctctcaga aagacatcac taaaggccca ttaaaaatct ggccctaaaa   4200

gttcaacttt tgtagagttt attgttcaga gaggtttaat cctatgtggt agtctatata   4260

agtgatgtat gagttgagtt atgtaaattt tgtcattgta gtgtacatgg agtgatcatt   4320

ttactaacat aaatattttc tatgtgtgtt tcagtggatg acaatcgagc agcagaagaa   4380

tggtgtgcct accctttaat gctgcagttt aagagaactt gtattgtgtc atttcagatt   4440

gtaggctgag agttgtaaat agtgaaaatt tgagtacttc tattatttgt tttggttaga   4500

aagtgaattt aaaaaacaaa ccaaactcta aactttctca gattaaaagt cctgagacct   4560

gaagattgta atattcatgt ctgtgaagct tttaaacatt acacttgaga tcagtcatga   4620

cttgatattc aggtaaattt tcttttccaa gaagcttttg aataagcata tttcctccaa   4680

aggtctctct ctttctctct ctttttttga gtgtagatta ttttaaagca ctaattgcat   4740

tacattggta actgcaatat aaaatagcca ttattgtttt gtgaagcatg gttgaaatta   4800

gctagtggtc ccttttgaat ttcatgagcc tctcaaaaaa gaaaaactta aaaaaaaaaa   4860

aaaaaaaaaa caaaaagctg ctggaatatt tcaaaagata tatattttac cttattatag   4920

gttttgtaaa gttagtttgt aatat                                         4945


<210>  7250
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  7250

Met Gln Arg Met Ile Gln Gln Phe Ala Ala Glu Tyr Thr Ser Lys Asn 
1               5                   10                  15


Ser Ser Thr Gln Asp Pro Ser Gln Pro Asn Ser Thr Lys Asn Gln Ser 
            20                  25                  30


Leu Pro Lys Ala Ser Pro Val Thr Thr Ser Pro Thr Ala Ala Thr Thr 
        35                  40                  45


Gln Asn Pro Val Leu Ser Lys Leu Leu Met Ala Asp Gln Asp Ser Pro 
    50                  55                  60


Leu Asp Leu Thr Val Arg Lys Ser Gln Ser Glu Pro Ser Glu Gln Asp 
65                  70                  75                  80


Gly Val Leu Asp Leu Ser Thr Lys Lys Ser Pro Cys Ala Gly Ser Thr 
                85                  90                  95


Ser Leu Ser His Ser Pro Gly Cys Ser Ser Thr Gln Gly Asn Gly Arg 
            100                 105                 110


Pro Gly Arg Pro Ser Gln Tyr Arg Pro Asp Gly Leu Arg Ser Gly Asp 
        115                 120                 125


Gly Val Pro Pro Arg Ser Leu Gln Asp Gly Thr Arg Glu Gly Phe Gly 
    130                 135                 140


His Ser Thr Ser Leu Lys Val Pro Leu Ala Arg Ser Leu Gln Ile Ser 
145                 150                 155                 160


Glu Glu Leu Leu Ser Arg Asn Gln Leu Ser Thr Ala Ala Ser Leu Gly 
                165                 170                 175


Pro Ser Gly Leu Gln Asn His Gly Gln His Leu Ile Leu Ser Arg Glu 
            180                 185                 190


Ala Ser Trp Ala Lys Pro His Tyr Glu Phe Asn Leu Ser Arg Met Lys 
        195                 200                 205


Phe Arg Gly Asn Gly Ala Leu Ser Asn Ile Ser Asp Leu Pro Phe Leu 
    210                 215                 220


Ala Glu Asn Ser Ala Phe Pro Lys Met Ala Leu Gln Ala Lys Gln Asp 
225                 230                 235                 240


Gly Lys Lys Asp Val Ser His Ser Ser Pro Val Asp Leu Lys Ile Pro 
                245                 250                 255


Gln Val Arg Gly Met Asp Leu Ser Trp Glu Ser Arg Thr Gly Asp Gln 
            260                 265                 270


Tyr Ser Tyr Ser Ser Leu Val Met Gly Ser Gln Thr Glu Ser Ala Leu 
        275                 280                 285


Ser Lys Lys Leu Arg Ala Ile Leu Pro Lys Gln Ser Arg Lys Ser Met 
    290                 295                 300


Leu Asp Ala Gly Pro Asp Ser Trp Gly Ser Asp Ala Glu Gln Ser Thr 
305                 310                 315                 320


Ser Gly Gln Pro Tyr Pro Thr Ser Asp Gln Glu Gly Asp Pro Gly Ser 
                325                 330                 335


Lys Gln Pro Arg Lys Lys Arg Gly Arg Tyr Arg Gln Tyr Asn Ser Glu 
            340                 345                 350


Ile Leu Glu Glu Ala Ile Ser Val Val Met Ser Gly Lys Met Ser Val 
        355                 360                 365


Ser Lys Ala Gln Ser Ile Tyr Gly Ile Pro His Ser Thr Leu Glu Tyr 
    370                 375                 380


Lys Val Lys Glu Arg Leu Gly Thr Leu Lys Asn Pro Pro Lys Lys Lys 
385                 390                 395                 400


Met Lys Leu Met Arg Ser Glu Gly Pro Asp Val Ser Val Lys Ile Glu 
                405                 410                 415


Leu Asp Pro Gln Gly Glu Ala Ala Gln Ser Ala Asn Glu Ser Lys Asn 
            420                 425                 430


Glu 



<210>  7251
<211>  563
<212>  DNA
<213>  Homo sapiens

<400>  7251
cctggggatt ataattaaca ccttcatttg tagcagtcta ttttgaatta ataacaactt     60

ggtttcaata gtatataaaa tactttgctg ctacatagct ctcccccctc caataaatct    120

ttatgcattg tttgtccatc aacacagagt tataattatt gttgtatgta gtcttttaag    180

tcatataggg aacaaaagag gcattaacaa actgaaaaca taacctctct gccttctttg    240

cttcctaaca ctttataata taatatctct aatatgcttt cagatactat tctaaataat    300

ttacaaatac ttgtctaatc acgttataaa tttatagcca aggaaagtga ggtgtgaaga    360

agacaaattc ctggccaata tggcgaaacc cggtctctac taaaaataca aaaactaact    420

gggcatggtg gtgggcatct gtagtcccag ctactcggga ggctgaggca ggagaattgc    480

ttgaaccctg gaggtggagg ttgcagtaag ccaagatcgc gccactacac tccagcctgg    540

gtgacagagc aagactctgt ttc                                            563


<210>  7252
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  7252

Gly Val Lys Lys Thr Asn Ser Trp Pro Ile Trp Arg Asn Pro Val Ser 
1               5                   10                  15


Thr Lys Asn Thr Lys Thr Asn Trp Ala Trp Trp Trp Ala Ser Val Val 
            20                  25                  30


Pro Ala Thr Arg Glu Ala Glu Ala Gly Glu Leu Leu Glu Pro Trp Arg 
        35                  40                  45


Trp Arg Leu Gln 
    50


<210>  7253
<211>  468
<212>  DNA
<213>  Homo sapiens

<400>  7253
ggctgtttgg acctgcatta ttaaaagatc tcagtttatt taaagactgt gaacctgaaa     60

gcatttctga ttggactttt gatgaaaact gtttattctg ttgcttgaga agagataaag    120

taaaggtaac taagaagcct gtgaaacttt tatttagtgt agtattttaa agttttcatc    180

ttttaaaaca ttgtgttact ttgttggagg atttgtagga aaaggaaggt atggtttcat    240

acttagttat gaaagagttt gatagtaatc ctgggttttg caatttaagt tatttccatc    300

ctgttgatta gcctattaag aaacctatat cctaccatgc atttattgtt gttattttgt    360

ttttttgctt ttttgttttt tttttatttt gagacggagt ctctctgtga tgcccaggct    420

ggagtgaaat ggcacgatct ctgctcactg cagccgccgc ctcctggg                 468


<210>  7254
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7254

Met His Leu Leu Leu Leu Phe Cys Phe Phe Ala Phe Leu Phe Phe Phe 
1               5                   10                  15


Tyr Phe Glu Thr Glu Ser Leu Cys Asp Ala Gln Ala Gly Val Lys Trp 
            20                  25                  30


His Asp Leu Cys Ser Leu Gln Pro Pro Pro Pro 
        35                  40


<210>  7255
<211>  2488
<212>  DNA
<213>  Homo sapiens

<400>  7255
aaggacaatt agtcactagc gagacccagt aggaagagag gtttaaatca gagggattga     60

atgagggtgc tttgtgcctt ccctgaagcc atgccctcca gcaactcccg cccccccgcg    120

tgcctagccc cgggggctct ctacttggct ctgttgctcc atctctccct ttcctcccag    180

gctggagaca ggagaccctt gcctgtagac agagctgcag gtttgaagga aaagaccctg    240

attctacttg atgtgagcac caagaaccca gtcaggacag tcaatgagaa cttcctctct    300

ctgcagctgg atccgtccat cattcatgat ggctggctcg atttcctaag ctccaagcgc    360

ttggtgaccc tggcccgggg actttcgccc gcctttctgc gcttcggggg caaaaggacc    420

gacttcctgc agttccagaa cctgaggaac ccggcgaaaa gccgcggggg cccgggcccg    480

gattactatc tcaaaaacta tgaggatgag ccaaataact atcggaccat gcatggccgg    540

gcagtaaatg gcagccagtt gggaaaggat tacatccagc tgaagagcct gttgcagccc    600

atccggattt attccagagc cagcttatat ggccctaata ttgggcggcc gaggaagaat    660

gtcatcgccc tcctagatgg attcatgaag gtggcaggaa gtacagtaga tgcagttacc    720

tggcaacatt gctacattga tggccgggtg gtcaaggtga tggacttcct gaaaactcgc    780

ctgttagaca cactctctga ccagattagg aaaattcaga aagtggttaa tacatacact    840

ccaggaaaga agatttggct tgaaggtgtg gtgaccacct cagctggagg cacaaacaat    900

ctatccgatt cctatgctgc aggattctta tggttgaaca ctttaggaat gctggccaat    960

cagggcattg atgtcgtgat acggcactca ttttttgacc atggatacaa tcacctcgtg   1020

gaccagaatt ttaacccatt accagactac tggctctctc tcctctacaa gcgcctgatc   1080

ggccccaaag tcttggctgt gcatgtggct gggctccagc ggaagccacg gcctggccga   1140

gtgatccggg acaaactaag gatttatgct cactgcacaa accaccacaa ccacaactac   1200

gttcgtgggt ccattacact ttttatcatc aacttgcatc gatcaagaaa gaaaatcaag   1260

ctggctggga ctctcagaga caagctggtt caccagtacc tgctgcagcc ctatgggcag   1320

gagggcctaa agtccaagtc agtgcaactg aatggccagc ccttagtgat ggtggacgac   1380

gggaccctcc cagaattgaa gccccgcccc cttcgggccg gccggacatt ggtcatccct   1440

ccagtcacca tgggctttta tgtggtcaag aatgtcaatg ctttggcctg ccgctaccga   1500

taagctatcc tcacactcac ggctaccagt gggcctgctg ggctgcttcc actcctccac   1560

tccagtagta tcctctgttt tcagacatcc tagcaaccag cccctgctgc cccatcctgc   1620

tggaatcaac acagacttgc tctccaaaga gactaaatgt catagcgtga tcttagccta   1680

ggtaggccac atccatccca aaggaaaatg tagacatcac ctgtacctat ataaggataa   1740

aggcatgtgt atagagcaga atgtttccct tcatgtgcac tatgaaaacg agctgacagc   1800

acactcccag gagaaatgtt tccagacaac tccccatgat cctgtcacac agcattataa   1860

ccacaaatcc aaaccttagc ctgctgctgc tgctgccctc agaggaagat gaggaaggaa   1920

aaaaactggg tggacctaca aaaacccatc ctctcccaac tccttcttct ctgcctcttt   1980

cttgctgctg ccctgagttt tttgacacat ctctttccat aggggagtaa tgggtgtgtc   2040

agccctggcc tgctgggaga gctgtttgta tgatttcccg gctgatgtat gagcgtgcgc   2100

atctgggttc ctgacagtgg catccatcac tggcagttct tctgggaagc gggtgcttca   2160

aaagtaaaat tacaatcaca ctccagattt ggtaagaagg ttctattcct ctgtgaatcc   2220

agattccccc agagttgtaa tgggagtcaa gtaacaatat tcattgagtg gagagcagtt   2280

tattaggcac aacaaaaagt agtcatcatt cttcatgttg ctatgaggga gagtttgagt   2340

acaaagagaa agcatactga aacatcaggt acacacacac accccaactg gacaaagcaa   2400

attagacctc tccaaaatta agagaatatt aggggctcta tagggtaagc ccttaattgt   2460

ttggttaact caaatcatta tttttaaa                                      2488


<210>  7256
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  7256

Met Arg Val Leu Cys Ala Phe Pro Glu Ala Met Pro Ser Ser Asn Ser 
1               5                   10                  15


Arg Pro Pro Ala Cys Leu Ala Pro Gly Ala Leu Tyr Leu Ala Leu Leu 
            20                  25                  30


Leu His Leu Ser Leu Ser Ser Gln Ala Gly Asp Arg Arg Pro Leu Pro 
        35                  40                  45


Val Asp Arg Ala Ala Gly Leu Lys Glu Lys Thr Leu Ile Leu Leu Asp 
    50                  55                  60


Val Ser Thr Lys Asn Pro Val Arg Thr Val Asn Glu Asn Phe Leu Ser 
65                  70                  75                  80


Leu Gln Leu Asp Pro Ser Ile Ile His Asp Gly Trp Leu Asp Phe Leu 
                85                  90                  95


Ser Ser Lys Arg Leu Val Thr Leu Ala Arg Gly Leu Ser Pro Ala Phe 
            100                 105                 110


Leu Arg Phe Gly Gly Lys Arg Thr Asp Phe Leu Gln Phe Gln Asn Leu 
        115                 120                 125


Arg Asn Pro Ala Lys Ser Arg Gly Gly Pro Gly Pro Asp Tyr Tyr Leu 
    130                 135                 140


Lys Asn Tyr Glu Asp Glu Pro Asn Asn Tyr Arg Thr Met His Gly Arg 
145                 150                 155                 160


Ala Val Asn Gly Ser Gln Leu Gly Lys Asp Tyr Ile Gln Leu Lys Ser 
                165                 170                 175


Leu Leu Gln Pro Ile Arg Ile Tyr Ser Arg Ala Ser Leu Tyr Gly Pro 
            180                 185                 190


Asn Ile Gly Arg Pro Arg Lys Asn Val Ile Ala Leu Leu Asp Gly Phe 
        195                 200                 205


Met Lys Val Ala Gly Ser Thr Val Asp Ala Val Thr Trp Gln His Cys 
    210                 215                 220


Tyr Ile Asp Gly Arg Val Val Lys Val Met Asp Phe Leu Lys Thr Arg 
225                 230                 235                 240


Leu Leu Asp Thr Leu Ser Asp Gln Ile Arg Lys Ile Gln Lys Val Val 
                245                 250                 255


Asn Thr Tyr Thr Pro Gly Lys Lys Ile Trp Leu Glu Gly Val Val Thr 
            260                 265                 270


Thr Ser Ala Gly Gly Thr Asn Asn Leu Ser Asp Ser Tyr Ala Ala Gly 
        275                 280                 285


Phe Leu Trp Leu Asn Thr Leu Gly Met Leu Ala Asn Gln Gly Ile Asp 
    290                 295                 300


Val Val Ile Arg His Ser Phe Phe Asp His Gly Tyr Asn His Leu Val 
305                 310                 315                 320


Asp Gln Asn Phe Asn Pro Leu Pro Asp Tyr Trp Leu Ser Leu Leu Tyr 
                325                 330                 335


Lys Arg Leu Ile Gly Pro Lys Val Leu Ala Val His Val Ala Gly Leu 
            340                 345                 350


Gln Arg Lys Pro Arg Pro Gly Arg Val Ile Arg Asp Lys Leu Arg Ile 
        355                 360                 365


Tyr Ala His Cys Thr Asn His His Asn His Asn Tyr Val Arg Gly Ser 
    370                 375                 380


Ile Thr Leu Phe Ile Ile Asn Leu His Arg Ser Arg Lys Lys Ile Lys 
385                 390                 395                 400


Leu Ala Gly Thr Leu Arg Asp Lys Leu Val His Gln Tyr Leu Leu Gln 
                405                 410                 415


Pro Tyr Gly Gln Glu Gly Leu Lys Ser Lys Ser Val Gln Leu Asn Gly 
            420                 425                 430


Gln Pro Leu Val Met Val Asp Asp Gly Thr Leu Pro Glu Leu Lys Pro 
        435                 440                 445


Arg Pro Leu Arg Ala Gly Arg Thr Leu Val Ile Pro Pro Val Thr Met 
    450                 455                 460


Gly Phe Tyr Val Val Lys Asn Val Asn Ala Leu Ala Cys Arg Tyr Arg 
465                 470                 475                 480


<210>  7257
<211>  2837
<212>  DNA
<213>  Homo sapiens

<400>  7257
acacacttta gataaggaca attagtcact agcgagaccc agtaggaaga gaggtttaaa     60

tcagagggat tgaatgaggg tgctttgtgc cttccctgaa gccatgccct ccagcaactc    120

ccgccccccc gcgtgcctag ccccgggggc tctctacttg gctctgttgc tccatctctc    180

cctttcctcc caggctggag acaggagacc cttgcctgta gacagagctg caggtttgaa    240

ggaaaagacc ctgattctac ttgatgtgag caccaagaac ccagtcagga cagtcaatga    300

gaacttcctc tctctgcagc tggatccgtc catcattcat gatggctggc tcgatttcct    360

aagctccaag cgcttggtga ccctggcccg gggactttcg cccgcctttc tgcgcttcgg    420

gggcaaaagg accgacttcc tgcagttcca gaacctgagg aacccggcga aaagccgcgg    480

gggcccgggc ccggattact atctcaaaaa ctatgaggat gacattgttc gaagtgatgt    540

tgccttagat aaacagaaag gctgcaagat tgcccagcac cctgatgtta tgctggagct    600

ccaaagggag aaggcagctc agatgcatct ggttcttcta aaggagcaat tctccaatac    660

ttacagtaat ctcatattaa cagccaggtc tctagacaaa ctttataact ttgctgattg    720

ctctggactc cacctgatat ttgctctaaa tgcactgcgt cgtaatccca ataactcctg    780

gaacagttct agtgccctga gtctgttgaa gtacagcgcc agcaaaaagt acaacatttc    840

ttgggaactg ggtaatgagc caaataacta tcggaccatg catggccggg cagtaaatgg    900

cagccagttg ggaaaggatt acatccagct gaagagcctg ttgcagccca tccggattta    960

ttccagagcc agcttatatg gccctaatat tgggcggccg aggaagaatg tcatcgccct   1020

cctagatgga ttcatgaagg tggcaggaag tacagtagat gcagttacct ggcaacattg   1080

ctacattgat ggccgggtgg tcaaggtgat ggacttcctg aaaactcgcc tgttagacac   1140

actctctgac cagattagga aaattcagaa agtggttaat acatacactc caggaaagaa   1200

gatttggctt gaaggtgtgg tgaccacctc agctggaggc acaaacaatc tatccgattc   1260

ctatgctgca ggattcttat ggttgaacac tttaggaatg ctggccaatc agggcattga   1320

tgtcgtgata cggcactcat tttttgacca tggatacaat cacctcgtgg accagaattt   1380

taacccatta ccagactact ggctctctct cctctacaag cgcctgatcg gccccaaagt   1440

cttggctgtg catgtggctg ggctccagcg gaagccacgg cctggccgag tgatccggga   1500

caaactaagg atttatgctc actgcacaaa ccaccacaac cacaactacg ttcgtgggtc   1560

cattacactt tttatcatca acttgcatcg atcaagaaag aaaatcaagc tggctgggac   1620

tctcagagac aagctggttc accagtacct gctgcagccc tatgggcagg agggcctaaa   1680

gtccaagtca gtgcaactga atggccagcc cttagtgatg gtggacgacg ggaccctccc   1740

agaattgaag ccccgccccc ttcgggccgg ccggacattg gtcatccctc cagtcaccat   1800

gggcttttat gtggtcaaga atgtcaatgc tttggcctgc cgctaccgat aagctatcct   1860

cacactcacg gctaccagtg ggcctgctgg gctgcttcca ctcctccact ccagtagtat   1920

cctctgtttt cagacatcct agcaaccagc ccctgctgcc ccatcctgct ggaatcaaca   1980

cagacttgct ctccaaagag actaaatgtc atagcgtgat cttagcctag gtaggccaca   2040

tccatcccaa aggaaaatgt agacatcacc tgtacctata taaggataaa ggcatgtgta   2100

tagagcagaa tgtttccctt catgtgcact atgaaaacga gctgacagca cactcccagg   2160

agaaatgttt ccagacaact ccccatgatc ctgtcacaca gcattataac cacaaatcca   2220

aaccttagcc tgctgctgct gctgccctca gaggaagatg aggaaggaaa aaaactgggt   2280

ggacctacaa aaacccatcc tctcccaact ccttcttctc tgcctctttc ttgctgctgc   2340

cctgagtttt ttgacacatc tctttccata ggggagtaat gggtgtgtca gccctggcct   2400

gctgggagag ctgtttgtat gatttcccgg ctgatgtatg agcgtgcgca tctgggttcc   2460

tgacagtggc atccatcact ggcagttctt ctgggaagcg ggtgcttcaa aagtaaaatt   2520

acaatcacac tccagatttg gtaagaaggt tctattcctc tgtgaatcca gattccccca   2580

gagttgtaat gggagtcaag taacaatatt cattgagtgg agagcagttt attaggcaca   2640

acaaaaagta gtcatcattc ttcatgttgc tatgagggag agtttgagta caaagagaaa   2700

gcatactgaa acatcaggta cacacacaca ccccaactgg acaaagcaaa ttagacctct   2760

ccaaaattaa gagaatatta ggggctctat agggtaagcc cttaattgtt tggttaactc   2820

aaatcattat ttttaaa                                                  2837


<210>  7258
<211>  592
<212>  PRT
<213>  Homo sapiens

<400>  7258

Met Arg Val Leu Cys Ala Phe Pro Glu Ala Met Pro Ser Ser Asn Ser 
1               5                   10                  15


Arg Pro Pro Ala Cys Leu Ala Pro Gly Ala Leu Tyr Leu Ala Leu Leu 
            20                  25                  30


Leu His Leu Ser Leu Ser Ser Gln Ala Gly Asp Arg Arg Pro Leu Pro 
        35                  40                  45


Val Asp Arg Ala Ala Gly Leu Lys Glu Lys Thr Leu Ile Leu Leu Asp 
    50                  55                  60


Val Ser Thr Lys Asn Pro Val Arg Thr Val Asn Glu Asn Phe Leu Ser 
65                  70                  75                  80


Leu Gln Leu Asp Pro Ser Ile Ile His Asp Gly Trp Leu Asp Phe Leu 
                85                  90                  95


Ser Ser Lys Arg Leu Val Thr Leu Ala Arg Gly Leu Ser Pro Ala Phe 
            100                 105                 110


Leu Arg Phe Gly Gly Lys Arg Thr Asp Phe Leu Gln Phe Gln Asn Leu 
        115                 120                 125


Arg Asn Pro Ala Lys Ser Arg Gly Gly Pro Gly Pro Asp Tyr Tyr Leu 
    130                 135                 140


Lys Asn Tyr Glu Asp Asp Ile Val Arg Ser Asp Val Ala Leu Asp Lys 
145                 150                 155                 160


Gln Lys Gly Cys Lys Ile Ala Gln His Pro Asp Val Met Leu Glu Leu 
                165                 170                 175


Gln Arg Glu Lys Ala Ala Gln Met His Leu Val Leu Leu Lys Glu Gln 
            180                 185                 190


Phe Ser Asn Thr Tyr Ser Asn Leu Ile Leu Thr Ala Arg Ser Leu Asp 
        195                 200                 205


Lys Leu Tyr Asn Phe Ala Asp Cys Ser Gly Leu His Leu Ile Phe Ala 
    210                 215                 220


Leu Asn Ala Leu Arg Arg Asn Pro Asn Asn Ser Trp Asn Ser Ser Ser 
225                 230                 235                 240


Ala Leu Ser Leu Leu Lys Tyr Ser Ala Ser Lys Lys Tyr Asn Ile Ser 
                245                 250                 255


Trp Glu Leu Gly Asn Glu Pro Asn Asn Tyr Arg Thr Met His Gly Arg 
            260                 265                 270


Ala Val Asn Gly Ser Gln Leu Gly Lys Asp Tyr Ile Gln Leu Lys Ser 
        275                 280                 285


Leu Leu Gln Pro Ile Arg Ile Tyr Ser Arg Ala Ser Leu Tyr Gly Pro 
    290                 295                 300


Asn Ile Gly Arg Pro Arg Lys Asn Val Ile Ala Leu Leu Asp Gly Phe 
305                 310                 315                 320


Met Lys Val Ala Gly Ser Thr Val Asp Ala Val Thr Trp Gln His Cys 
                325                 330                 335


Tyr Ile Asp Gly Arg Val Val Lys Val Met Asp Phe Leu Lys Thr Arg 
            340                 345                 350


Leu Leu Asp Thr Leu Ser Asp Gln Ile Arg Lys Ile Gln Lys Val Val 
        355                 360                 365


Asn Thr Tyr Thr Pro Gly Lys Lys Ile Trp Leu Glu Gly Val Val Thr 
    370                 375                 380


Thr Ser Ala Gly Gly Thr Asn Asn Leu Ser Asp Ser Tyr Ala Ala Gly 
385                 390                 395                 400


Phe Leu Trp Leu Asn Thr Leu Gly Met Leu Ala Asn Gln Gly Ile Asp 
                405                 410                 415


Val Val Ile Arg His Ser Phe Phe Asp His Gly Tyr Asn His Leu Val 
            420                 425                 430


Asp Gln Asn Phe Asn Pro Leu Pro Asp Tyr Trp Leu Ser Leu Leu Tyr 
        435                 440                 445


Lys Arg Leu Ile Gly Pro Lys Val Leu Ala Val His Val Ala Gly Leu 
    450                 455                 460


Gln Arg Lys Pro Arg Pro Gly Arg Val Ile Arg Asp Lys Leu Arg Ile 
465                 470                 475                 480


Tyr Ala His Cys Thr Asn His His Asn His Asn Tyr Val Arg Gly Ser 
                485                 490                 495


Ile Thr Leu Phe Ile Ile Asn Leu His Arg Ser Arg Lys Lys Ile Lys 
            500                 505                 510


Leu Ala Gly Thr Leu Arg Asp Lys Leu Val His Gln Tyr Leu Leu Gln 
        515                 520                 525


Pro Tyr Gly Gln Glu Gly Leu Lys Ser Lys Ser Val Gln Leu Asn Gly 
    530                 535                 540


Gln Pro Leu Val Met Val Asp Asp Gly Thr Leu Pro Glu Leu Lys Pro 
545                 550                 555                 560


Arg Pro Leu Arg Ala Gly Arg Thr Leu Val Ile Pro Pro Val Thr Met 
                565                 570                 575


Gly Phe Tyr Val Val Lys Asn Val Asn Ala Leu Ala Cys Arg Tyr Arg 
            580                 585                 590


<210>  7259
<211>  2663
<212>  DNA
<213>  Homo sapiens

<400>  7259
acacacttta gataaggaca attagtcact agcgagaccc agtaggaaga gaggtttaaa     60

tcagagggat tgaatgaggg tgctttgtgc cttccctgaa gccatgccct ccagcaactc    120

ccgccccccc gcgtgcctag ccccgggggc tctctacttg gctctgttgc tccatctctc    180

cctttcctcc caggctggag acaggagacc cttgcctgta gacagagctg caggtttgaa    240

ggaaaagacc ctgattctac ttgatgtgag caccaagaac ccagtcagga cagtcaatga    300

gaacttcctc tctctgcagc tggatccgtc catcattcat gatggctggc tcgatttcct    360

aagctccaag cgcttggtga ccctggcccg gggactttcg cccgcctttc tgcgcttcgg    420

gggcaaaagg accgacttcc tgcagttcca gaacctgagg aacccggcga aaagccgcgg    480

gggcccgggc ccggattact atctcaaaaa ctatgaggat gacattgttc gaagtgatgt    540

tgccttagat aaacagaaag gctgcaagat tgcccagcac cctgatgtta tgctggagct    600

ccaaagggag aaggcagctc agatgcatct ggttcttcta aaggagcaat tctccaatac    660

ttacagtaat ctcatattaa cagagccaaa taactatcgg accatgcatg gccgggcagt    720

aaatggcagc cagttgggaa aggattacat ccagctgaag agcctgttgc agcccatccg    780

gatttattcc agagccagct tatatggccc taatattggg cggccgagga agaatgtcat    840

cgccctccta gatggattca tgaaggtggc aggaagtaca gtagatgcag ttacctggca    900

acattgctac attgatggcc gggtggtcaa ggtgatggac ttcctgaaaa ctcgcctgtt    960

agacacactc tctgaccaga ttaggaaaat tcagaaagtg gttaatacat acactccagg   1020

aaagaagatt tggcttgaag gtgtggtgac cacctcagct ggaggcacaa acaatctatc   1080

cgattcctat gctgcaggat tcttatggtt gaacacttta ggaatgctgg ccaatcaggg   1140

cattgatgtc gtgatacggc actcattttt tgaccatgga tacaatcacc tcgtggacca   1200

gaattttaac ccattaccag actactggct ctctctcctc tacaagcgcc tgatcggccc   1260

caaagtcttg gctgtgcatg tggctgggct ccagcggaag ccacggcctg gccgagtgat   1320

ccgggacaaa ctaaggattt atgctcactg cacaaaccac cacaaccaca actacgttcg   1380

tgggtccatt acacttttta tcatcaactt gcatcgatca agaaagaaaa tcaagctggc   1440

tgggactctc agagacaagc tggttcacca gtacctgctg cagccctatg ggcaggaggg   1500

cctaaagtcc aagtcagtgc aactgaatgg ccagccctta gtgatggtgg acgacgggac   1560

cctcccagaa ttgaagcccc gcccccttcg ggccggccgg acattggtca tccctccagt   1620

caccatgggc ttttatgtgg tcaagaatgt caatgctttg gcctgccgct accgataagc   1680

tatcctcaca ctcacggcta ccagtgggcc tgctgggctg cttccactcc tccactccag   1740

tagtatcctc tgttttcaga catcctagca accagcccct gctgccccat cctgctggaa   1800

tcaacacaga cttgctctcc aaagagacta aatgtcatag cgtgatctta gcctaggtag   1860

gccacatcca tcccaaagga aaatgtagac atcacctgta cctatataag gataaaggca   1920

tgtgtataga gcagaatgtt tcccttcatg tgcactatga aaacgagctg acagcacact   1980

cccaggagaa atgtttccag acaactcccc atgatcctgt cacacagcat tataaccaca   2040

aatccaaacc ttagcctgct gctgctgctg ccctcagagg aagatgagga aggaaaaaaa   2100

ctgggtggac ctacaaaaac ccatcctctc ccaactcctt cttctctgcc tctttcttgc   2160

tgctgccctg agttttttga cacatctctt tccatagggg agtaatgggt gtgtcagccc   2220

tggcctgctg ggagagctgt ttgtatgatt tcccggctga tgtatgagcg tgcgcatctg   2280

ggttcctgac agtggcatcc atcactggca gttcttctgg gaagcgggtg cttcaaaagt   2340

aaaattacaa tcacactcca gatttggtaa gaaggttcta ttcctctgtg aatccagatt   2400

cccccagagt tgtaatggga gtcaagtaac aatattcatt gagtggagag cagtttatta   2460

ggcacaacaa aaagtagtca tcattcttca tgttgctatg agggagagtt tgagtacaaa   2520

gagaaagcat actgaaacat caggtacaca cacacacccc aactggacaa agcaaattag   2580

acctctccaa aattaagaga atattagggg ctctataggg taagccctta attgtttggt   2640

taactcaaat cattattttt aaa                                           2663


<210>  7260
<211>  534
<212>  PRT
<213>  Homo sapiens

<400>  7260

Met Arg Val Leu Cys Ala Phe Pro Glu Ala Met Pro Ser Ser Asn Ser 
1               5                   10                  15


Arg Pro Pro Ala Cys Leu Ala Pro Gly Ala Leu Tyr Leu Ala Leu Leu 
            20                  25                  30


Leu His Leu Ser Leu Ser Ser Gln Ala Gly Asp Arg Arg Pro Leu Pro 
        35                  40                  45


Val Asp Arg Ala Ala Gly Leu Lys Glu Lys Thr Leu Ile Leu Leu Asp 
    50                  55                  60


Val Ser Thr Lys Asn Pro Val Arg Thr Val Asn Glu Asn Phe Leu Ser 
65                  70                  75                  80


Leu Gln Leu Asp Pro Ser Ile Ile His Asp Gly Trp Leu Asp Phe Leu 
                85                  90                  95


Ser Ser Lys Arg Leu Val Thr Leu Ala Arg Gly Leu Ser Pro Ala Phe 
            100                 105                 110


Leu Arg Phe Gly Gly Lys Arg Thr Asp Phe Leu Gln Phe Gln Asn Leu 
        115                 120                 125


Arg Asn Pro Ala Lys Ser Arg Gly Gly Pro Gly Pro Asp Tyr Tyr Leu 
    130                 135                 140


Lys Asn Tyr Glu Asp Asp Ile Val Arg Ser Asp Val Ala Leu Asp Lys 
145                 150                 155                 160


Gln Lys Gly Cys Lys Ile Ala Gln His Pro Asp Val Met Leu Glu Leu 
                165                 170                 175


Gln Arg Glu Lys Ala Ala Gln Met His Leu Val Leu Leu Lys Glu Gln 
            180                 185                 190


Phe Ser Asn Thr Tyr Ser Asn Leu Ile Leu Thr Glu Pro Asn Asn Tyr 
        195                 200                 205


Arg Thr Met His Gly Arg Ala Val Asn Gly Ser Gln Leu Gly Lys Asp 
    210                 215                 220


Tyr Ile Gln Leu Lys Ser Leu Leu Gln Pro Ile Arg Ile Tyr Ser Arg 
225                 230                 235                 240


Ala Ser Leu Tyr Gly Pro Asn Ile Gly Arg Pro Arg Lys Asn Val Ile 
                245                 250                 255


Ala Leu Leu Asp Gly Phe Met Lys Val Ala Gly Ser Thr Val Asp Ala 
            260                 265                 270


Val Thr Trp Gln His Cys Tyr Ile Asp Gly Arg Val Val Lys Val Met 
        275                 280                 285


Asp Phe Leu Lys Thr Arg Leu Leu Asp Thr Leu Ser Asp Gln Ile Arg 
    290                 295                 300


Lys Ile Gln Lys Val Val Asn Thr Tyr Thr Pro Gly Lys Lys Ile Trp 
305                 310                 315                 320


Leu Glu Gly Val Val Thr Thr Ser Ala Gly Gly Thr Asn Asn Leu Ser 
                325                 330                 335


Asp Ser Tyr Ala Ala Gly Phe Leu Trp Leu Asn Thr Leu Gly Met Leu 
            340                 345                 350


Ala Asn Gln Gly Ile Asp Val Val Ile Arg His Ser Phe Phe Asp His 
        355                 360                 365


Gly Tyr Asn His Leu Val Asp Gln Asn Phe Asn Pro Leu Pro Asp Tyr 
    370                 375                 380


Trp Leu Ser Leu Leu Tyr Lys Arg Leu Ile Gly Pro Lys Val Leu Ala 
385                 390                 395                 400


Val His Val Ala Gly Leu Gln Arg Lys Pro Arg Pro Gly Arg Val Ile 
                405                 410                 415


Arg Asp Lys Leu Arg Ile Tyr Ala His Cys Thr Asn His His Asn His 
            420                 425                 430


Asn Tyr Val Arg Gly Ser Ile Thr Leu Phe Ile Ile Asn Leu His Arg 
        435                 440                 445


Ser Arg Lys Lys Ile Lys Leu Ala Gly Thr Leu Arg Asp Lys Leu Val 
    450                 455                 460


His Gln Tyr Leu Leu Gln Pro Tyr Gly Gln Glu Gly Leu Lys Ser Lys 
465                 470                 475                 480


Ser Val Gln Leu Asn Gly Gln Pro Leu Val Met Val Asp Asp Gly Thr 
                485                 490                 495


Leu Pro Glu Leu Lys Pro Arg Pro Leu Arg Ala Gly Arg Thr Leu Val 
            500                 505                 510


Ile Pro Pro Val Thr Met Gly Phe Tyr Val Val Lys Asn Val Asn Ala 
        515                 520                 525


Leu Ala Cys Arg Tyr Arg 
    530


<210>  7261
<211>  2907
<212>  DNA
<213>  Homo sapiens

<400>  7261
acacacttta gataaggaca attagtcact agcgagaccc agtaggaaga gaggtttaaa     60

tcagagggat tgaatgaggg tgctttgtgc cttccctgaa gccatgccct ccagcaactc    120

ccgccccccc gcgtgcctag ccccgggggc tctctacttg gctctgttgc tccatctctc    180

cctttcctcc caggctggag acaggagacc cttgcctgta gacagagctg caggtttgaa    240

ggaaaagacc ctgattctac ttgatgtgag caccaagaac ccagtcagga cagtcaatga    300

gaacttcctc tctctgcagc tggatccgtc catcattcat gatggctggc tcgatttcct    360

aagctccaag cgcttggtga ccctggcccg gggactttcg cccgcctttc tgcgcttcgg    420

gggcaaaagg accgacttcc tgcagttcca gaacctgagg aacccggcga aaagccgcgg    480

gggcccgggc ccggattact atctcaaaaa ctatgaggat gacattgttc gaagtgatgt    540

tgccttagat aaacagaaag gctgcaagat tgcccagcac cctgatgtta tgctggagct    600

ccaaagggag aaggcagctc agatgcatct ggttcttcta aaggagcaat tctccaatac    660

ttacagtaat ctcatattaa cagccaggtc tctagacaaa ctttataact ttgctgattg    720

ctctggactc cacctgatat ttgctctaaa tgcactgcgt cgtaatccca ataactcctg    780

gaacagttct agtgccctga gtctgttgaa gtacagcgcc agcaaaaagt acaacatttc    840

ttgggaactg ggtaatgagc caaataacta tcggaccatg catggccggg cagtaaatgg    900

cagccagttg ggaaaggatt acatccagct gaagagcctg ttgcagccca tccggattta    960

ttccagagcc agcttatatg gccctaatat tgggcggccg aggaagaatg tcatcgccct   1020

cctagatgga ttcatgaagg tggcaggaag tacagtagat gcagttacct ggcaacattg   1080

ctacattgat ggccgggtgg tcaaggtgat ggacttcctg aaaactcgcc tgttagacac   1140

actctctgac cagattagga aaattcagaa agtggttaat acatacactc caggaaagaa   1200

gatttggctt gaaggtgtgg tgaccacctc agctggaggc acaaacaatc tatccgattc   1260

ctatgctgca ggattcttat ggttgaacac tttaggaatg ctggccaatc agggcattga   1320

tgtcgtgata cggcactcat tttttgacca tggatacaat cacctcgtgg accagaattt   1380

taacccatta ccagactact ggctctctct cctctacaag cgcctgatcg gccccaaagt   1440

cttggctgtg catgtggctg ggctccagcg gaagccacgg cctggccgag tgatccggga   1500

caaactaagg atttatgctc actgcacaaa ccaccacaac cacaactacg ttcgtgggtc   1560

cattacactt tttatcatca acttgcatcg atcaagaaag aaaatcaagc tggctgggac   1620

tctcagagac aagctggttc accagtacct gctgcagccc tatgggcagg agggcctaaa   1680

gtccaaaacc caaagatgtc aatactgtgg gatcatctga atctaaaagg gcattaccta   1740

attcttcaga agaaaggtca gtgcaactga atggccagcc cttagtgatg gtggacgacg   1800

ggaccctccc agaattgaag ccccgccccc ttcgggccgg ccggacattg gtcatccctc   1860

cagtcaccat gggcttttat gtggtcaaga atgtcaatgc tttggcctgc cgctaccgat   1920

aagctatcct cacactcacg gctaccagtg ggcctgctgg gctgcttcca ctcctccact   1980

ccagtagtat cctctgtttt cagacatcct agcaaccagc ccctgctgcc ccatcctgct   2040

ggaatcaaca cagacttgct ctccaaagag actaaatgtc atagcgtgat cttagcctag   2100

gtaggccaca tccatcccaa aggaaaatgt agacatcacc tgtacctata taaggataaa   2160

ggcatgtgta tagagcagaa tgtttccctt catgtgcact atgaaaacga gctgacagca   2220

cactcccagg agaaatgttt ccagacaact ccccatgatc ctgtcacaca gcattataac   2280

cacaaatcca aaccttagcc tgctgctgct gctgccctca gaggaagatg aggaaggaaa   2340

aaaactgggt ggacctacaa aaacccatcc tctcccaact ccttcttctc tgcctctttc   2400

ttgctgctgc cctgagtttt ttgacacatc tctttccata ggggagtaat gggtgtgtca   2460

gccctggcct gctgggagag ctgtttgtat gatttcccgg ctgatgtatg agcgtgcgca   2520

tctgggttcc tgacagtggc atccatcact ggcagttctt ctgggaagcg ggtgcttcaa   2580

aagtaaaatt acaatcacac tccagatttg gtaagaaggt tctattcctc tgtgaatcca   2640

gattccccca gagttgtaat gggagtcaag taacaatatt cattgagtgg agagcagttt   2700

attaggcaca acaaaaagta gtcatcattc ttcatgttgc tatgagggag agtttgagta   2760

caaagagaaa gcatactgaa acatcaggta cacacacaca ccccaactgg acaaagcaaa   2820

ttagacctct ccaaaattaa gagaatatta ggggctctat agggtaagcc cttaattgtt   2880

tggttaactc aaatcattat ttttaaa                                       2907


<210>  7262
<211>  548
<212>  PRT
<213>  Homo sapiens

<400>  7262

Met Arg Val Leu Cys Ala Phe Pro Glu Ala Met Pro Ser Ser Asn Ser 
1               5                   10                  15


Arg Pro Pro Ala Cys Leu Ala Pro Gly Ala Leu Tyr Leu Ala Leu Leu 
            20                  25                  30


Leu His Leu Ser Leu Ser Ser Gln Ala Gly Asp Arg Arg Pro Leu Pro 
        35                  40                  45


Val Asp Arg Ala Ala Gly Leu Lys Glu Lys Thr Leu Ile Leu Leu Asp 
    50                  55                  60


Val Ser Thr Lys Asn Pro Val Arg Thr Val Asn Glu Asn Phe Leu Ser 
65                  70                  75                  80


Leu Gln Leu Asp Pro Ser Ile Ile His Asp Gly Trp Leu Asp Phe Leu 
                85                  90                  95


Ser Ser Lys Arg Leu Val Thr Leu Ala Arg Gly Leu Ser Pro Ala Phe 
            100                 105                 110


Leu Arg Phe Gly Gly Lys Arg Thr Asp Phe Leu Gln Phe Gln Asn Leu 
        115                 120                 125


Arg Asn Pro Ala Lys Ser Arg Gly Gly Pro Gly Pro Asp Tyr Tyr Leu 
    130                 135                 140


Lys Asn Tyr Glu Asp Asp Ile Val Arg Ser Asp Val Ala Leu Asp Lys 
145                 150                 155                 160


Gln Lys Gly Cys Lys Ile Ala Gln His Pro Asp Val Met Leu Glu Leu 
                165                 170                 175


Gln Arg Glu Lys Ala Ala Gln Met His Leu Val Leu Leu Lys Glu Gln 
            180                 185                 190


Phe Ser Asn Thr Tyr Ser Asn Leu Ile Leu Thr Ala Arg Ser Leu Asp 
        195                 200                 205


Lys Leu Tyr Asn Phe Ala Asp Cys Ser Gly Leu His Leu Ile Phe Ala 
    210                 215                 220


Leu Asn Ala Leu Arg Arg Asn Pro Asn Asn Ser Trp Asn Ser Ser Ser 
225                 230                 235                 240


Ala Leu Ser Leu Leu Lys Tyr Ser Ala Ser Lys Lys Tyr Asn Ile Ser 
                245                 250                 255


Trp Glu Leu Gly Asn Glu Pro Asn Asn Tyr Arg Thr Met His Gly Arg 
            260                 265                 270


Ala Val Asn Gly Ser Gln Leu Gly Lys Asp Tyr Ile Gln Leu Lys Ser 
        275                 280                 285


Leu Leu Gln Pro Ile Arg Ile Tyr Ser Arg Ala Ser Leu Tyr Gly Pro 
    290                 295                 300


Asn Ile Gly Arg Pro Arg Lys Asn Val Ile Ala Leu Leu Asp Gly Phe 
305                 310                 315                 320


Met Lys Val Ala Gly Ser Thr Val Asp Ala Val Thr Trp Gln His Cys 
                325                 330                 335


Tyr Ile Asp Gly Arg Val Val Lys Val Met Asp Phe Leu Lys Thr Arg 
            340                 345                 350


Leu Leu Asp Thr Leu Ser Asp Gln Ile Arg Lys Ile Gln Lys Val Val 
        355                 360                 365


Asn Thr Tyr Thr Pro Gly Lys Lys Ile Trp Leu Glu Gly Val Val Thr 
    370                 375                 380


Thr Ser Ala Gly Gly Thr Asn Asn Leu Ser Asp Ser Tyr Ala Ala Gly 
385                 390                 395                 400


Phe Leu Trp Leu Asn Thr Leu Gly Met Leu Ala Asn Gln Gly Ile Asp 
                405                 410                 415


Val Val Ile Arg His Ser Phe Phe Asp His Gly Tyr Asn His Leu Val 
            420                 425                 430


Asp Gln Asn Phe Asn Pro Leu Pro Asp Tyr Trp Leu Ser Leu Leu Tyr 
        435                 440                 445


Lys Arg Leu Ile Gly Pro Lys Val Leu Ala Val His Val Ala Gly Leu 
    450                 455                 460


Gln Arg Lys Pro Arg Pro Gly Arg Val Ile Arg Asp Lys Leu Arg Ile 
465                 470                 475                 480


Tyr Ala His Cys Thr Asn His His Asn His Asn Tyr Val Arg Gly Ser 
                485                 490                 495


Ile Thr Leu Phe Ile Ile Asn Leu His Arg Ser Arg Lys Lys Ile Lys 
            500                 505                 510


Leu Ala Gly Thr Leu Arg Asp Lys Leu Val His Gln Tyr Leu Leu Gln 
        515                 520                 525


Pro Tyr Gly Gln Glu Gly Leu Lys Ser Lys Thr Gln Arg Cys Gln Tyr 
    530                 535                 540


Cys Gly Ile Ile 
545


<210>  7263
<211>  557
<212>  DNA
<213>  Homo sapiens

<400>  7263
ctctagcccc ggccaggtcg ccctcaggga gtaggaagag ggcccttctc cgtgccccac     60

gcgctctcgt cctgtcctgg gaacctttcc tctcttattc tcttcctctg cagctccaag    120

cgcttggtga ccctggcccg gggactttcg cccgcctttc tgcgcttcgg gggcaaaagg    180

accgacttcc tgcagttcca gaacctgagg aacccggcga aaagccgcgg gggcccgggc    240

ccggattact atctcaaaaa ctatgaggat gacattgttc gaagtgatgt tgccttagat    300

aaacagaaag gctgcaagat tgcccagcac cctgatgtta tgctggagct ccaaagggag    360

aaggcagctc agatgcatct ggttcttcta aaggagcaat tctccaatac ttacagtaat    420

ctcatattaa caggaatttg tatggagctg ggcttcatta gactctttta aatgtacaaa    480

aatgccaacc acactttgca gacatgatgt tttcaggcac tattcatgaa ggtggcagga    540

agtacagtag atgcagt                                                   557


<210>  7264
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7264

Met Leu Glu Leu Gln Arg Glu Lys Ala Ala Gln Met His Leu Val Leu 
1               5                   10                  15


Leu Lys Glu Gln Phe Ser Asn Thr Tyr Ser Asn Leu Ile Leu Thr Gly 
            20                  25                  30


Ile Cys Met Glu Leu Gly Phe Ile Arg Leu Phe 
        35                  40


<210>  7265
<211>  580
<212>  DNA
<213>  Homo sapiens

<400>  7265
acagagcctc tagccccggc caggtcgccc tcagggagta ggaagagggc ccttctccgt     60

gccccacgcg ctctcgtcct gtcctgggaa cctttcctct cttattctct tcctctgcag    120

ctccaagcgc ttggtgaccc tggcccgggg actttcgccc gcctttctgc gcttcggggg    180

caaaaggacc gacttcctgc agttccagaa cctgaggaac ccggcgaaaa gccgcggggg    240

cccgggcccg gattactatc tcaaaaacta tgaggatgac attgttcgaa gtgatgttgc    300

cttagataaa cagaaaggct gcaagattgc ccagcaccct gatgttatgc tggagctcca    360

aagggagaag gcagctcaga tgcatctggt tcttctaaag gagcaattct ccaatactta    420

cagtaatctc atattaacag ccaggtctct agacaaactt tataactttg ctgattgctc    480

tggactccac ctgatatttg ctctaaatgc actgcgtcgt aatcccaata actcctggaa    540

cagttctagt gccctgagtc tgttgaagta cagcgccagc                          580


<210>  7266
<211>  77
<212>  PRT
<213>  Homo sapiens

<400>  7266

Met Leu Glu Leu Gln Arg Glu Lys Ala Ala Gln Met His Leu Val Leu 
1               5                   10                  15


Leu Lys Glu Gln Phe Ser Asn Thr Tyr Ser Asn Leu Ile Leu Thr Ala 
            20                  25                  30


Arg Ser Leu Asp Lys Leu Tyr Asn Phe Ala Asp Cys Ser Gly Leu His 
        35                  40                  45


Leu Ile Phe Ala Leu Asn Ala Leu Arg Arg Asn Pro Asn Asn Ser Trp 
    50                  55                  60


Asn Ser Ser Ser Ala Leu Ser Leu Leu Lys Tyr Ser Ala 
65                  70                  75


<210>  7267
<211>  574
<212>  DNA
<213>  Homo sapiens

<400>  7267
aaggacaatt agtcactagc gagacccagt aggaagagag gtttaaatca gagggattga     60

atgagggtgc tttgtgcctt ccctgaagcc atgccctcca gcaactcccg cccccccgcg    120

tgcctagccc cgggggctct ctacttggct ctgttgctcc atctctccct ttcctcccag    180

gctggagaca ggagaccctt gcctgtagac agagctgcag gtttgaagga aaagaccctg    240

attctacttg atgtgagcac caagaaccca gtcaggacag tcaatgagaa cttcctctct    300

ctgcagctgg atccgtccat cattcatgat ggctggctcg atttcctaag ctccaagcgc    360

ttggtgaccc tggcccgggg actttcgccc gcctttctgc gcttcggggg caaaaggacc    420

gacttcctgc agttccagaa cctgaggaac ccggcgaaaa gccgcggggg cccgggcccg    480

gattactatc tcaaaaacta tgaggatgcc aggtctctag acaaacttta taactttgct    540

gattgctctg gactccacct gatatttgct ctaa                                574


<210>  7268
<211>  170
<212>  PRT
<213>  Homo sapiens

<400>  7268

Met Arg Val Leu Cys Ala Phe Pro Glu Ala Met Pro Ser Ser Asn Ser 
1               5                   10                  15


Arg Pro Pro Ala Cys Leu Ala Pro Gly Ala Leu Tyr Leu Ala Leu Leu 
            20                  25                  30


Leu His Leu Ser Leu Ser Ser Gln Ala Gly Asp Arg Arg Pro Leu Pro 
        35                  40                  45


Val Asp Arg Ala Ala Gly Leu Lys Glu Lys Thr Leu Ile Leu Leu Asp 
    50                  55                  60


Val Ser Thr Lys Asn Pro Val Arg Thr Val Asn Glu Asn Phe Leu Ser 
65                  70                  75                  80


Leu Gln Leu Asp Pro Ser Ile Ile His Asp Gly Trp Leu Asp Phe Leu 
                85                  90                  95


Ser Ser Lys Arg Leu Val Thr Leu Ala Arg Gly Leu Ser Pro Ala Phe 
            100                 105                 110


Leu Arg Phe Gly Gly Lys Arg Thr Asp Phe Leu Gln Phe Gln Asn Leu 
        115                 120                 125


Arg Asn Pro Ala Lys Ser Arg Gly Gly Pro Gly Pro Asp Tyr Tyr Leu 
    130                 135                 140


Lys Asn Tyr Glu Asp Ala Arg Ser Leu Asp Lys Leu Tyr Asn Phe Ala 
145                 150                 155                 160


Asp Cys Ser Gly Leu His Leu Ile Phe Ala 
                165                 170


<210>  7269
<211>  3297
<212>  DNA
<213>  Homo sapiens

<400>  7269
gcgccgagcg cgggtttccg ctcggggcgg gcgatagaga cagcgcgtcg cgcctttagc     60

ttctttccca gactccggcc cagctcctgc gatctccaca gcagcctctg aggccgcccc    120

cagagagcat caggatggct gaggaaaagg gtggaaagca agtcctggaa gaatctgcat    180

ttgaagaaat ggaaagagat tttcagggag ttctccatga actttctgga gacaaaagtt    240

tggaaaaatt tcggattgaa tatgagaggc ttcatgctgt catgaaaaag tcttatgaca    300

atgaaaagcg tctgatggcc aaatgcagag agctaaatgc agagattgta gtgaattctg    360

cgaaggtcgc cactgccctt aagctctctc aggatgatca gaccaccatt gcatccctaa    420

agaaggaaat tgaaaaggcc tggaagatgg tggactcagc ctatgacaaa gagcagaagg    480

ccaaggagac gattcttgct ctgaaagagg aaatagtgaa cctgaccaaa ctagtggagc    540

aggggtctgg actgtcaatg gaccagcata gcaacatccg agatttactg aggttcaaag    600

aagaagtgac aaaggagaga gaccagctct tatcagaagt ggtaaaatta cgagaatccc    660

tagctcagac cactgaacag cagcaggaaa cagagcgatc aaaagaggag gctgaacatg    720

ccatcagtca gttccaacaa gaaatccagc aacgtcagaa cgaagcttcc cgggagttcc    780

ggaagaagga aaaactagag aaagagctca agcagattca ggcagacatg gacagcaggc    840

agacagaaat aaaagccctg cagcagtatg tgcagaagag caaggaggag cttcagaagc    900

tggagcagca gctgaaggag cagaagatat tgaatgagag agctgcaaag gaactcgagc    960

aatttcagat gagaaatgct aaacttcagc aagagaatga acagcacagt ttggtctgtg   1020

agcagctatc ccaggaaaac caacagaagg cgttggagct caaagccaaa gaggaagaag   1080

tccatcaaat gcgccttgac atcgggaagc tcaacaaaat cagagaacaa attcataaga   1140

aattgcacca caccgaagat caaaaggcag aagtcgaaca gcacaaagaa accctaaaaa   1200

atcagattgt gggattagag agagaggtag aggcttcaaa gaaacaagca gaacttgaca   1260

gaaaggcaat ggacgagctt ctaagagaaa gggacatact aaataagaac atgcttaagg   1320

cggtcaatgc gacccagaag cagacagact tggtaaagct ccatgaacaa gccaagagga   1380

acctggaggg agaaatccag aactacaagg atgaggctca gaagcagaga aagatcatct   1440

ttcatctgga aaaggagcgt gaccggtaca tcaaccaagc cagtgacctt acgcaaaagg   1500

tccttatgaa catggaagac ataaaagttc gtgaaacaca gatttttgac tacaggaaaa   1560

aaatagctga atcagagatt aaattaaaac agcaacagaa cctatatgaa gctgtgagat   1620

cagacagaaa tctgtatagc aaaaatctgg ttgaggctca ggatgaaata acagatatga   1680

agagaaagtt aaagattatg atccatcagg tagatgagct gaaagaagac atctctgcca   1740

aagagtccgc acttgtgaag ctgcacctgg aacagcagcg aatagaaaag gaaaaggaaa   1800

cattgaaggc tgagctgcag aagctgagac aacaagccct ggagacaaaa cactttattg   1860

aaaagcaaga agctgaagag agaaaactcc tgcgaataat tgctgaggct gacggggaga   1920

ggttgagaca gaagaaggaa ttagaccagg tcatcagtga gagagatatc ctggggtctc   1980

agcttgttcg gcgcaatgat gagttagctt tgctctatga gaagatcaag atccaacagt   2040

ctgtgctgaa taaaggggag agccagtaca accagaggtt ggaggacatg agaatcctca   2100

gacttgagat caagaagctt cgccgggaaa aggggattct tgccaggagt atggctaatg   2160

ttgaagaact cagacaggag ttttttcaca tgcaaagaga attgttgaag gagaggacac   2220

gctgccgagc cctggaggag gagctggaga atcccctgaa tgtgcacaga tggaggaagc   2280

tcgaggccag cgaccccaat gcatatgagc tgatacagaa aattcacacc ctgcagaagc   2340

gtctcatcag caagactgaa gaggtggttg aaaaagagct gctcctccag gaaaaggaga   2400

aactctacat ggaactaaag cacgtcttgg cccgccagcc tggacctgag gctgcggaac   2460

agctgaagct gtaccgacgc acgctgcatg acaagaagca gcagctgaaa gttttgtctt   2520

cagaattgaa tatgtatgaa gtacagagca aagaatataa atatgaggta gagaaactta   2580

ccaatgagct ccagaattta aagaagaaat acctcgctca gaaacgtaaa gaacaacttc   2640

aaaaaaacaa ggacacagca cccatggata acaccttctt aatggtcaaa ccaaatggtc   2700

ctggttttac tgggggcgga tttcctctca ggtcaaccaa aatgacgttc taacctgaag   2760

ctgctggctg tttccagttg aacaactcat gaaatctgct ctgggacatt ttgggggaat   2820

ctcaaagtcc ttggatcata gaactgagtg ctgagaatcc aggatggaaa gaaatgcaga   2880

actatcatag tcacatacat ataagaggga tggtgttttg tctggttcac gttgatatta   2940

acagatcata attctctctg ttcagttagg ctgacctatt gcatgaagca aatcttttgt   3000

tgctacccca ttgattgaaa tgtactagac cttaatttct ttattacaga cattggtgta   3060

cttgaaggtt ttatatttaa aagtattttt gaaatgcaat gtgtcccctc tcaccttatt   3120

aacaataatc tattttaatt attcctcatt aacaagtcat tgcatgagat gagaaagaag   3180

gacaaactct taagaattta aaaagtgttt tgagaatgat ttctatatgg aatttctttt   3240

caggcccgga atgggaaaat ctattccaaa gagacacact aataaatact tcattat      3297


<210>  7270
<211>  872
<212>  PRT
<213>  Homo sapiens

<400>  7270

Met Ala Glu Glu Lys Gly Gly Lys Gln Val Leu Glu Glu Ser Ala Phe 
1               5                   10                  15


Glu Glu Met Glu Arg Asp Phe Gln Gly Val Leu His Glu Leu Ser Gly 
            20                  25                  30


Asp Lys Ser Leu Glu Lys Phe Arg Ile Glu Tyr Glu Arg Leu His Ala 
        35                  40                  45


Val Met Lys Lys Ser Tyr Asp Asn Glu Lys Arg Leu Met Ala Lys Cys 
    50                  55                  60


Arg Glu Leu Asn Ala Glu Ile Val Val Asn Ser Ala Lys Val Ala Thr 
65                  70                  75                  80


Ala Leu Lys Leu Ser Gln Asp Asp Gln Thr Thr Ile Ala Ser Leu Lys 
                85                  90                  95


Lys Glu Ile Glu Lys Ala Trp Lys Met Val Asp Ser Ala Tyr Asp Lys 
            100                 105                 110


Glu Gln Lys Ala Lys Glu Thr Ile Leu Ala Leu Lys Glu Glu Ile Val 
        115                 120                 125


Asn Leu Thr Lys Leu Val Glu Gln Gly Ser Gly Leu Ser Met Asp Gln 
    130                 135                 140


His Ser Asn Ile Arg Asp Leu Leu Arg Phe Lys Glu Glu Val Thr Lys 
145                 150                 155                 160


Glu Arg Asp Gln Leu Leu Ser Glu Val Val Lys Leu Arg Glu Ser Leu 
                165                 170                 175


Ala Gln Thr Thr Glu Gln Gln Gln Glu Thr Glu Arg Ser Lys Glu Glu 
            180                 185                 190


Ala Glu His Ala Ile Ser Gln Phe Gln Gln Glu Ile Gln Gln Arg Gln 
        195                 200                 205


Asn Glu Ala Ser Arg Glu Phe Arg Lys Lys Glu Lys Leu Glu Lys Glu 
    210                 215                 220


Leu Lys Gln Ile Gln Ala Asp Met Asp Ser Arg Gln Thr Glu Ile Lys 
225                 230                 235                 240


Ala Leu Gln Gln Tyr Val Gln Lys Ser Lys Glu Glu Leu Gln Lys Leu 
                245                 250                 255


Glu Gln Gln Leu Lys Glu Gln Lys Ile Leu Asn Glu Arg Ala Ala Lys 
            260                 265                 270


Glu Leu Glu Gln Phe Gln Met Arg Asn Ala Lys Leu Gln Gln Glu Asn 
        275                 280                 285


Glu Gln His Ser Leu Val Cys Glu Gln Leu Ser Gln Glu Asn Gln Gln 
    290                 295                 300


Lys Ala Leu Glu Leu Lys Ala Lys Glu Glu Glu Val His Gln Met Arg 
305                 310                 315                 320


Leu Asp Ile Gly Lys Leu Asn Lys Ile Arg Glu Gln Ile His Lys Lys 
                325                 330                 335


Leu His His Thr Glu Asp Gln Lys Ala Glu Val Glu Gln His Lys Glu 
            340                 345                 350


Thr Leu Lys Asn Gln Ile Val Gly Leu Glu Arg Glu Val Glu Ala Ser 
        355                 360                 365


Lys Lys Gln Ala Glu Leu Asp Arg Lys Ala Met Asp Glu Leu Leu Arg 
    370                 375                 380


Glu Arg Asp Ile Leu Asn Lys Asn Met Leu Lys Ala Val Asn Ala Thr 
385                 390                 395                 400


Gln Lys Gln Thr Asp Leu Val Lys Leu His Glu Gln Ala Lys Arg Asn 
                405                 410                 415


Leu Glu Gly Glu Ile Gln Asn Tyr Lys Asp Glu Ala Gln Lys Gln Arg 
            420                 425                 430


Lys Ile Ile Phe His Leu Glu Lys Glu Arg Asp Arg Tyr Ile Asn Gln 
        435                 440                 445


Ala Ser Asp Leu Thr Gln Lys Val Leu Met Asn Met Glu Asp Ile Lys 
    450                 455                 460


Val Arg Glu Thr Gln Ile Phe Asp Tyr Arg Lys Lys Ile Ala Glu Ser 
465                 470                 475                 480


Glu Ile Lys Leu Lys Gln Gln Gln Asn Leu Tyr Glu Ala Val Arg Ser 
                485                 490                 495


Asp Arg Asn Leu Tyr Ser Lys Asn Leu Val Glu Ala Gln Asp Glu Ile 
            500                 505                 510


Thr Asp Met Lys Arg Lys Leu Lys Ile Met Ile His Gln Val Asp Glu 
        515                 520                 525


Leu Lys Glu Asp Ile Ser Ala Lys Glu Ser Ala Leu Val Lys Leu His 
    530                 535                 540


Leu Glu Gln Gln Arg Ile Glu Lys Glu Lys Glu Thr Leu Lys Ala Glu 
545                 550                 555                 560


Leu Gln Lys Leu Arg Gln Gln Ala Leu Glu Thr Lys His Phe Ile Glu 
                565                 570                 575


Lys Gln Glu Ala Glu Glu Arg Lys Leu Leu Arg Ile Ile Ala Glu Ala 
            580                 585                 590


Asp Gly Glu Arg Leu Arg Gln Lys Lys Glu Leu Asp Gln Val Ile Ser 
        595                 600                 605


Glu Arg Asp Ile Leu Gly Ser Gln Leu Val Arg Arg Asn Asp Glu Leu 
    610                 615                 620


Ala Leu Leu Tyr Glu Lys Ile Lys Ile Gln Gln Ser Val Leu Asn Lys 
625                 630                 635                 640


Gly Glu Ser Gln Tyr Asn Gln Arg Leu Glu Asp Met Arg Ile Leu Arg 
                645                 650                 655


Leu Glu Ile Lys Lys Leu Arg Arg Glu Lys Gly Ile Leu Ala Arg Ser 
            660                 665                 670


Met Ala Asn Val Glu Glu Leu Arg Gln Glu Phe Phe His Met Gln Arg 
        675                 680                 685


Glu Leu Leu Lys Glu Arg Thr Arg Cys Arg Ala Leu Glu Glu Glu Leu 
    690                 695                 700


Glu Asn Pro Leu Asn Val His Arg Trp Arg Lys Leu Glu Ala Ser Asp 
705                 710                 715                 720


Pro Asn Ala Tyr Glu Leu Ile Gln Lys Ile His Thr Leu Gln Lys Arg 
                725                 730                 735


Leu Ile Ser Lys Thr Glu Glu Val Val Glu Lys Glu Leu Leu Leu Gln 
            740                 745                 750


Glu Lys Glu Lys Leu Tyr Met Glu Leu Lys His Val Leu Ala Arg Gln 
        755                 760                 765


Pro Gly Pro Glu Ala Ala Glu Gln Leu Lys Leu Tyr Arg Arg Thr Leu 
    770                 775                 780


His Asp Lys Lys Gln Gln Leu Lys Val Leu Ser Ser Glu Leu Asn Met 
785                 790                 795                 800


Tyr Glu Val Gln Ser Lys Glu Tyr Lys Tyr Glu Val Glu Lys Leu Thr 
                805                 810                 815


Asn Glu Leu Gln Asn Leu Lys Lys Lys Tyr Leu Ala Gln Lys Arg Lys 
            820                 825                 830


Glu Gln Leu Gln Lys Asn Lys Asp Thr Ala Pro Met Asp Asn Thr Phe 
        835                 840                 845


Leu Met Val Lys Pro Asn Gly Pro Gly Phe Thr Gly Gly Gly Phe Pro 
    850                 855                 860


Leu Arg Ser Thr Lys Met Thr Phe 
865                 870


<210>  7271
<211>  3330
<212>  DNA
<213>  Homo sapiens

<400>  7271
gcgccgagcg cgggtttccg ctcggggcgg gcgatagaga cagcgcgtcg cgcctttagc     60

ttctttccca gactccggcc cagctcctgc gatctccaca gcagcctctg aggccgcccc    120

cagagagcat caggatggct gaggaaaagg gtggaaagca agtcctggaa gaatctgcat    180

ttgaagaaat ggaaagagat tttcagggag ttctccatga actttctgga gacaaaagtt    240

tggaaaaatt tcggattgaa tatgagaggc ttcatgctgt catgaaaaag tcttatgaca    300

atgaaaagcg tctgatggcc aaatgcagag agctaaatgc agagattgta gtgaattctg    360

cgaaggtcgc cactgccctt aagctctctc aggatgatca gaccaccatt gcatccctaa    420

agaaggaaat tgaaaaggcc tggaagatgg tggactcagc ctatgacaaa gagcagaagg    480

ccaaggagac gattcttgct ctgaaagagg aaatagtgaa cctgaccaaa ctagtggagc    540

aggggtctgg actgtcaatg gaccagcata gcaacatccg agatttactg aggttcaaag    600

aagaagtgac aaaggagaga gaccagctct tatcagaagt ggtaaaatta cgagaatccc    660

tagctcagac cactgaacag cagcaggaaa cagagcgatc aaaagaggag gctgaacatg    720

ccatcagtca gttccaacaa gaaatccagc aacgtcagaa cgaagcttcc cgggagttcc    780

ggaagaagga aaaactagag aaagagctca agcagattca ggcagacatg gacagcaggc    840

agacagaaat aaaagccctg cagcagtatg tgcagaagag caaggaggag cttcagaagc    900

tggagcagca gctgaaggag cagaagatat tgaatgagag agctgcaaag gaactcgagc    960

aatttcagat gagaaatgct aaacttcagc aagagaatga acagcacagt ttggtctgtg   1020

agcagctatc ccaggaaaac caacagaagg cgttggagct caaagccaaa gaggaagaag   1080

tccatcaaat gcgccttgac atcgggaagc tcaacaaaat cagagaacaa attcataaga   1140

aattgcacca caccgaagat caaaaggcag aagtcgaaca gcacaaagaa accctaaaaa   1200

atcagattgt gggattagag agagaggtag aggcttcaaa gaaacaagca gaacttgaca   1260

gaaaggcaat ggacgagctt ctaagagaaa gggacatact aaataagaac atgcttaagg   1320

cggtcaatgc gacccagaag cagacagact tggtaaagct ccatgaacaa gccaagagga   1380

acctggaggg agaaatccag aactacaagg atgaggctca gaagcagaga aagatcatct   1440

ttcatctgga aaaggagcgt gaccggtaca tcaaccaagc cagtgacctt acgcaaaagg   1500

tccttatgaa catggaagac ataaaagttc gtgaaacaca gatttttgac tacaggaaaa   1560

aaatagctga atcagagatt aaattaaaac agcaacagaa cctatatgaa gctgtgagat   1620

cagacagaaa tctgtatagc aaaaatctgg ttgaggctca ggatgaaata acagatatga   1680

agagaaagtt aaagattatg atccatcagg tagatgagct gaaagaagac atctctgcca   1740

aagagtccgc acttgtgaag ctgcacctgg aacagcagcg aatagaaaag gaaaaggaaa   1800

cattgaaggc tgagctgcag aagctgagac aacaagccct ggagacaaaa cactttattg   1860

aaaagcaaga agctgaagag agaaaactcc tgcgaataat tgctgaggct gacggggaga   1920

ggttgagaca gaagaaggaa ttagaccagg tcatcagtga gagagatatc ctggggtctc   1980

agcttgttcg gcgcaatgat gagttagctt tgctctatga gaagatcaag atccaacagt   2040

ctgtgctgaa taaaggggag agccagtaca accagaggtt ggaggacatg agaatcctca   2100

gacttgagat caagaagctt cgccgggaaa aggggattct tgccaggagt atggctaatg   2160

ttgaagaact cagacaggag ttttttcaca tgcaaagaga attgttgaag gagaggacac   2220

gctgccgagc cctggaggag gagctggaga atcccctgaa tgtgcacaga tggaggaagc   2280

tcgaggccag cgaccccaat gcatatgagc tgatacagaa aattcacacc ctgcagaagc   2340

gtctcatcag caagactgaa gaggtggttg aaaaagagct gctcctccag gaaaaggaga   2400

aactctacat ggaactaaag cacgtcttgg cccgccagcc tggacctgag gctgcggaac   2460

agctgaagct gtaccgacgc acgctgcatg acaagaagca gcagctgaaa gttttgtctt   2520

cagaattgaa tatgtatgaa gtacagagca aagaatataa atatgaggta gagaaactta   2580

ccaatgagct ccagaattta aagaagaaat acctcgctca gaaacgtaaa gaacaacttc   2640

aaaaaaacaa ggacacagca cccatggata acaccttctt aatggtcaaa ccaaatggtc   2700

ctggttttac tgggggcgga tttcctctca ggtcaaccaa aatgacgttc taacctgaag   2760

ctgctggctg tttccagttg aacaactcat gaaatctgct ctgggacatt ttgggggaat   2820

ctcaaagtcc ttggatcata gaactgagtg ctgagaatcc aggatggaaa gaaatgcaga   2880

actatcatag tcacatacat ataagaggga tggtgttttg tctggttcac gttgatatta   2940

acagatcata attctctctg ttcagttagg ctgacctatt gcatgaagca aatcttttgt   3000

tgctacccca ttgattgaaa tgtactagac cttaatttct ttattacaga cattggtgta   3060

cttgaaggtt ttatatttaa aagtattttt gaaatgcaat gtgtcccctc tcaccttatt   3120

aacaataatc tattttaatt attcctcatt aacaagtcat tgcatgagat gagaaagaag   3180

gacaaactct taagaattta aaaagtgttt tgagaatgat ttctatatgg aatttctttt   3240

caggcccgga atgggaaaat ctattccaaa gagacacact aataaatact tcattataaa   3300

aaataaaaaa gaatctttgt agagattttg                                    3330


<210>  7272
<211>  872
<212>  PRT
<213>  Homo sapiens

<400>  7272

Met Ala Glu Glu Lys Gly Gly Lys Gln Val Leu Glu Glu Ser Ala Phe 
1               5                   10                  15


Glu Glu Met Glu Arg Asp Phe Gln Gly Val Leu His Glu Leu Ser Gly 
            20                  25                  30


Asp Lys Ser Leu Glu Lys Phe Arg Ile Glu Tyr Glu Arg Leu His Ala 
        35                  40                  45


Val Met Lys Lys Ser Tyr Asp Asn Glu Lys Arg Leu Met Ala Lys Cys 
    50                  55                  60


Arg Glu Leu Asn Ala Glu Ile Val Val Asn Ser Ala Lys Val Ala Thr 
65                  70                  75                  80


Ala Leu Lys Leu Ser Gln Asp Asp Gln Thr Thr Ile Ala Ser Leu Lys 
                85                  90                  95


Lys Glu Ile Glu Lys Ala Trp Lys Met Val Asp Ser Ala Tyr Asp Lys 
            100                 105                 110


Glu Gln Lys Ala Lys Glu Thr Ile Leu Ala Leu Lys Glu Glu Ile Val 
        115                 120                 125


Asn Leu Thr Lys Leu Val Glu Gln Gly Ser Gly Leu Ser Met Asp Gln 
    130                 135                 140


His Ser Asn Ile Arg Asp Leu Leu Arg Phe Lys Glu Glu Val Thr Lys 
145                 150                 155                 160


Glu Arg Asp Gln Leu Leu Ser Glu Val Val Lys Leu Arg Glu Ser Leu 
                165                 170                 175


Ala Gln Thr Thr Glu Gln Gln Gln Glu Thr Glu Arg Ser Lys Glu Glu 
            180                 185                 190


Ala Glu His Ala Ile Ser Gln Phe Gln Gln Glu Ile Gln Gln Arg Gln 
        195                 200                 205


Asn Glu Ala Ser Arg Glu Phe Arg Lys Lys Glu Lys Leu Glu Lys Glu 
    210                 215                 220


Leu Lys Gln Ile Gln Ala Asp Met Asp Ser Arg Gln Thr Glu Ile Lys 
225                 230                 235                 240


Ala Leu Gln Gln Tyr Val Gln Lys Ser Lys Glu Glu Leu Gln Lys Leu 
                245                 250                 255


Glu Gln Gln Leu Lys Glu Gln Lys Ile Leu Asn Glu Arg Ala Ala Lys 
            260                 265                 270


Glu Leu Glu Gln Phe Gln Met Arg Asn Ala Lys Leu Gln Gln Glu Asn 
        275                 280                 285


Glu Gln His Ser Leu Val Cys Glu Gln Leu Ser Gln Glu Asn Gln Gln 
    290                 295                 300


Lys Ala Leu Glu Leu Lys Ala Lys Glu Glu Glu Val His Gln Met Arg 
305                 310                 315                 320


Leu Asp Ile Gly Lys Leu Asn Lys Ile Arg Glu Gln Ile His Lys Lys 
                325                 330                 335


Leu His His Thr Glu Asp Gln Lys Ala Glu Val Glu Gln His Lys Glu 
            340                 345                 350


Thr Leu Lys Asn Gln Ile Val Gly Leu Glu Arg Glu Val Glu Ala Ser 
        355                 360                 365


Lys Lys Gln Ala Glu Leu Asp Arg Lys Ala Met Asp Glu Leu Leu Arg 
    370                 375                 380


Glu Arg Asp Ile Leu Asn Lys Asn Met Leu Lys Ala Val Asn Ala Thr 
385                 390                 395                 400


Gln Lys Gln Thr Asp Leu Val Lys Leu His Glu Gln Ala Lys Arg Asn 
                405                 410                 415


Leu Glu Gly Glu Ile Gln Asn Tyr Lys Asp Glu Ala Gln Lys Gln Arg 
            420                 425                 430


Lys Ile Ile Phe His Leu Glu Lys Glu Arg Asp Arg Tyr Ile Asn Gln 
        435                 440                 445


Ala Ser Asp Leu Thr Gln Lys Val Leu Met Asn Met Glu Asp Ile Lys 
    450                 455                 460


Val Arg Glu Thr Gln Ile Phe Asp Tyr Arg Lys Lys Ile Ala Glu Ser 
465                 470                 475                 480


Glu Ile Lys Leu Lys Gln Gln Gln Asn Leu Tyr Glu Ala Val Arg Ser 
                485                 490                 495


Asp Arg Asn Leu Tyr Ser Lys Asn Leu Val Glu Ala Gln Asp Glu Ile 
            500                 505                 510


Thr Asp Met Lys Arg Lys Leu Lys Ile Met Ile His Gln Val Asp Glu 
        515                 520                 525


Leu Lys Glu Asp Ile Ser Ala Lys Glu Ser Ala Leu Val Lys Leu His 
    530                 535                 540


Leu Glu Gln Gln Arg Ile Glu Lys Glu Lys Glu Thr Leu Lys Ala Glu 
545                 550                 555                 560


Leu Gln Lys Leu Arg Gln Gln Ala Leu Glu Thr Lys His Phe Ile Glu 
                565                 570                 575


Lys Gln Glu Ala Glu Glu Arg Lys Leu Leu Arg Ile Ile Ala Glu Ala 
            580                 585                 590


Asp Gly Glu Arg Leu Arg Gln Lys Lys Glu Leu Asp Gln Val Ile Ser 
        595                 600                 605


Glu Arg Asp Ile Leu Gly Ser Gln Leu Val Arg Arg Asn Asp Glu Leu 
    610                 615                 620


Ala Leu Leu Tyr Glu Lys Ile Lys Ile Gln Gln Ser Val Leu Asn Lys 
625                 630                 635                 640


Gly Glu Ser Gln Tyr Asn Gln Arg Leu Glu Asp Met Arg Ile Leu Arg 
                645                 650                 655


Leu Glu Ile Lys Lys Leu Arg Arg Glu Lys Gly Ile Leu Ala Arg Ser 
            660                 665                 670


Met Ala Asn Val Glu Glu Leu Arg Gln Glu Phe Phe His Met Gln Arg 
        675                 680                 685


Glu Leu Leu Lys Glu Arg Thr Arg Cys Arg Ala Leu Glu Glu Glu Leu 
    690                 695                 700


Glu Asn Pro Leu Asn Val His Arg Trp Arg Lys Leu Glu Ala Ser Asp 
705                 710                 715                 720


Pro Asn Ala Tyr Glu Leu Ile Gln Lys Ile His Thr Leu Gln Lys Arg 
                725                 730                 735


Leu Ile Ser Lys Thr Glu Glu Val Val Glu Lys Glu Leu Leu Leu Gln 
            740                 745                 750


Glu Lys Glu Lys Leu Tyr Met Glu Leu Lys His Val Leu Ala Arg Gln 
        755                 760                 765


Pro Gly Pro Glu Ala Ala Glu Gln Leu Lys Leu Tyr Arg Arg Thr Leu 
    770                 775                 780


His Asp Lys Lys Gln Gln Leu Lys Val Leu Ser Ser Glu Leu Asn Met 
785                 790                 795                 800


Tyr Glu Val Gln Ser Lys Glu Tyr Lys Tyr Glu Val Glu Lys Leu Thr 
                805                 810                 815


Asn Glu Leu Gln Asn Leu Lys Lys Lys Tyr Leu Ala Gln Lys Arg Lys 
            820                 825                 830


Glu Gln Leu Gln Lys Asn Lys Asp Thr Ala Pro Met Asp Asn Thr Phe 
        835                 840                 845


Leu Met Val Lys Pro Asn Gly Pro Gly Phe Thr Gly Gly Gly Phe Pro 
    850                 855                 860


Leu Arg Ser Thr Lys Met Thr Phe 
865                 870


<210>  7273
<211>  1011
<212>  DNA
<213>  Homo sapiens

<400>  7273
ggttgccaaa tggtgttttg ggctcttctt ttcccaagaa gagactagcc cattgtcacc     60

aatgcagagc tggaagctga aattgttaag gcagaatgaa agggagaaaa gcacgtcctg    120

agcaccaaga agaagataac tcgaagttaa gaagacgtga tggtactttg gagaagaaag    180

caacacctga gtcaaattgc actgagcaac gttctttgtt gttgtgagat attgataaat    240

ctccaggtct tcaacaaggg gagtcgagaa taggaaactc atttcaaatc atatctcagg    300

tgacaagaag gttaccatat ttgaggcagc ctgttgggtt gcctgacggc gaaaatctac    360

agaacattct gccttacatt gctggagact gtctcctaca acttgagtct ttgatactgg    420

tgtcactttc aggagctcta agaatacgtc aactctcgct tctgagttgg tgacccctca    480

accaagaaag gacggtgatc tcattcctct cagcaggagt gttgagctca gacaactatg    540

aaaaccaaaa atcatcccag gtaggttata agggattgaa gagaaccaga gagtggctca    600

ttcataggaa gaagctgtga tttggcacca tgtgagcgtc gtcagagata aatgaagatc    660

caacactgcc agagctttca aatctccaag agaagcattc aacctgaatt ggtatgtgaa    720

atgtctcagt ttttaaaagt tgacaaccaa atcagaaaat aattttaaac accatgtagg    780

cccaatgaaa cacatctcca agccagatcc aaatcacaga attccaatca caggttgaaa    840

tccacttctc taaaatcttt tcgtctctga ccgggcatgg tggcacacgt ctgtagtccc    900

agctactcag gaggccaagg taggagaatt gcttgagccc tggagttcga cgctagcctg    960

ggcaacacag cacgactcag tctctaaaag taaaaataaa atattttctc c            1011


<210>  7274
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7274

Met Lys Gly Arg Lys Ala Arg Pro Glu His Gln Glu Glu Asp Asn Ser 
1               5                   10                  15


Lys Leu Arg Arg Arg Asp Gly Thr Leu Glu Lys Lys Ala Thr Pro Glu 
            20                  25                  30


Ser Asn Cys Thr Glu Gln Arg Ser Leu Leu Leu 
        35                  40


<210>  7275
<211>  7344
<212>  DNA
<213>  Homo sapiens

<400>  7275
atgtgggacc agtgtgggaa ggtcttgttt atgtgggagg ggggaccaca gataacaaag     60

aacagcccct tgcccccctc attgaaaacc agctgtgcat ctagacctct gtcttcccac    120

agtgccgcca agctcctgga caagaaccca ttctcggtca gtaacccgaa ccctctgctt    180

ccttcacctg ccagtctcca gctggctcaa ctgcaggccc agctcaccct ccaccggctg    240

aagctggcac agacagctgt caccaacaac actgcagccg ccacagtcct gaaccaagtc    300

ctctccaaag tggccatgtc ccagcctctc ttcaatcaac tgaggcatcc gtctgtgatc    360

actggccccc acggccatgc tggggttccc caacatgctg cagccatacc cagtacccgg    420

tttccctcta atgcaattgc cttttcaccc cccagccaga cacgaggccc cggaccctcc    480

atgaaccttc ccaaccagcc acccagtgcc atggtgatgc atcctttcac tggggtaatg    540

cctcagaccc ctggccagcc agcagtcatc ttgggcattg gcaagactgg gcctgctcca    600

gctacagcag gattctatga gtatggcaaa gccagctctg gccagacata tggccctgaa    660

acagatggtc agcctggctt cctgccatcc tcggcctcaa cctcgggcag tgtgacctat    720

gaagggcact acagccacac agggcaggat ggtcaagctg ccttttccaa agatttttac    780

ggacccaact cccaaggttc acatgtggcc agcggatttc cagctgagca ggctgggggc    840

ctgaaaagtg aggtcgggcc actgctgcag ggcacaaaca gccaatggga gagcccccat    900

ggattctcgg gccaaagcaa gcctgatctc acagcaggtc ccatgtggcc tccaccccac    960

aaccagccct atgagctgta cgaccccgag gaaccaacct cagacaggac acctccttcc   1020

ttcgggggtc ggcttaacaa cagcaaacag ggttttatcg gtgctgggcg gagggccaag   1080

gaggaccagg cgttgctatc tgtgcggccc ctgcaggctc atgagctgaa cgactttcac   1140

ggtgtggccc ccctccactt gccgcatatc tgtagcatct gtgacaagaa ggtgtttgat   1200

ttgaaggact gggagctgca tgtgaaaggg aagctgcacg ctcagaaatg cctggtcttc   1260

tctgaaaaga gccggtttcc ctttctcgcc ctctccagtg ctggcatccg gtgtatactt   1320

ggttcggcag agggaacatt gtgtgcttct cccaacagca cagctgttta taaccctgct   1380

gggaatgaag gtgagcaagg ccctacaggt cagcagcttg aagcagaagt gggctaccca   1440

caggcacatt atgtcctgtc tttaataacc aggacttccc tgatgtcccc ttctcacgga   1500

tgtagaaagc aaacagatcc caagacacta aaatgcattg ggcctgctgt ctgggcccat   1560

cagtattctc tgagatactt gagacgtaaa gctttgctga ttatcagcat gtccagagtt   1620

tccagggatg ttgaagctgc taaacaggtg aatcgtccaa gatccgtagg caatcctatg   1680

gatttaccag taaaatttgc acagcggaaa ggggctggcc gtgtggtgca catctgcaat   1740

ctccctgaag gaagctgcac tgagaatgac gtcattaacc tggggctgcc ctttggaaag   1800

gtcactaatt acatcctcat gaagtcgact aatcaggcct ttttagagat ggcttacaca   1860

gaagctgcac aggccatggt ccagtattat caagaaaaat ctgctgtgat caatggtgag   1920

aagttgctca ttcggatgtc caagagatac aaggaattgc agctcaagaa acccgggaag   1980

gccgtggctg ccatcatcca ggacatccat tcccagaggg agagggacat gttccgggaa   2040

gcagacagat atggcccaga aaggccgcgg tctcgtagtc cggtgagccg gtcactctcc   2100

ccgaggtccc acactcccag cttcacctcc tgcagctctt cccacagccc tccgggcccc   2160

tcccgggctg actggggcaa tggccgggac tcctgggagc actctcccta tgccaggagg   2220

gaggaagagc gagacccggc tccctggagg gacaacggag atgacaagag ggacaggatg   2280

gacccctggg cacatgatcg caaacaccac ccccggcaac tggacaaggc tgagttggac   2340

gagcgaccag aaggagggag gccccaccgg gagaagtacc cgagatctgg gtctcccaac   2400

ctgccccact ctgtgtccag ctacaaaagc cgtgaagacg gctactaccg gaaagagccc   2460

aaagccaagt gggacaagta tctgaagcag cagcaggatg cccccgggag gtccaggagg   2520

aaagacgagg ccaggctgcg ggaaagcaga cacccccatc cggatgactc aggcaaggaa   2580

gatgggctgg ggccaaaggt cactagggcc cctgagggcg ccaaggccaa gcagaatgag   2640

aaaaataaaa ccaagagaac tgatagagac caagaaggag ctgatgatag aaaagaaaac   2700

acaatggcag agaatgaggc tggaaaagag gaacaggagg gcatggaaga aagccctcaa   2760

tcagtgggca gacaggagaa agaagcagag ttctctgatc cggaaaacac aaggacaaag   2820

aaggaacaag attgggagag tgaaagtgag gcagaggggg agagctggta tcccactaac   2880

atggaggagc tggtgacagt ggacgaggtt ggggaagaag aagattttat cgtggaacca   2940

gacatcccag agctggaaga aattgtgccc attgaccaga aagacaaaat ttgcccagaa   3000

acatgtctgt gtgtgacaac caccttagac ttagacctgg cccaggattt ccccaaggaa   3060

ggagtcaagg ccgtagggaa tggggctgca gaaatcagcc tcaagtcacc cagagaactg   3120

ccctctgctt ccacaagctg tcccagtgac atggacgtgg aaatgcctgg cctaaatctg   3180

gatgctgagc ggaagccagc tgaaagtgag acaggcctct ccctggagga ttcagattgc   3240

tacgagaagg aggcaaaggg agtggagagc tcagatgttc atccagcccc tacagtccag   3300

caaatgtctt cccctaagcc agcagaggag agggcccggc agccaagccc atttgtggat   3360

gattgcaaga ccagggggac ccccgaagat ggggcttgtg aaggcagccc cctggaggag   3420

aaagccagcc cccccatcga aactgacctc caaaaccaag cttgccaaga agtgttgacc   3480

ccggaaaact ccaggtacgt ggaaatgaaa tctctggagg tgaggtcacc agagtacact   3540

gaagtggaac tgaaacagcc cctttctttg ccctcttggg aaccagagga tgtgttcagt   3600

gaacttagca ttcctctagg ggtggagttc gtggttccca ggactggctt ttattgcaag   3660

ctgtgtgggc tgttctacac gagcgaggag acagcaaaga tgagccactg ccgcagcgct   3720

gtccactaca ggaacttaca gaaatatttg tcccagctgg ccgaggaggg cctcaaggag   3780

accgaggggg cagatagccc gaggccagag gacagcggaa tcgtgccacg cttcgaaagg   3840

aaaaagctct gatgcttctg cttctgctgc tactgctgct gctgcaaggt tggaaaggag   3900

agcttgctga agtggggcct tcctgattct ggggacagga ctaaagcctg agaggaagga   3960

aaaccaagca gggcacattg cttgggcttg ttcccagaga ctcagtgaaa tgcccctgat   4020

atgtctccag gagcaagtca cccaggtgtg tccagcccac tgagggtcac caactctctc   4080

cctgctgact cttgtttctc tcaatctttc aattcgtttt tctctctttt cctcttgttc   4140

tttctctccc tccctcctta tgtgccaagg atcgtttcct tttcacaaaa cccaacttct   4200

cagggatttt cacagtgttt aaattcttgg taggatataa caggtcaggc ctagctgagt   4260

caggcaagga aaaggtttaa tggaaactcc tgggtcaggc gaacccctgc agtgagtcta   4320

cagcagtatc tctgcctggt gtcccatgta tcccctgcat gaggagctga gtcaggtctg   4380

cagtcctggt gaggggacat cacggacaat ctgttggcag agctgggagg gtcttcatta   4440

acctcttcct ccaactgggc cacccttttg aaaagcccct gtttttaata actgtttcat   4500

cctctcagtt attctagaaa tctgccagac ttatgcctta aagtaaaatt aaatgaattt   4560

tagagaagat gaaaagagcc cttcattttg gaagctctga taagtttcct ccaaacttat   4620

tcccctcctc ttgatttcag gagatgtcag ggtttttcta ttctggacaa tgaatttggt   4680

acagagtcac tgtaattaaa tataaaaaca gaagcatctt cctccagcta aagcagcagt   4740

tggcgcgggc ttaggttgaa tgctggcctc tctgcaaagc acagctttgg ctcgagaggc   4800

acagctccag gctgtggaaa acagagttgt cttgggggtt aaatgagctt atttaagtca   4860

aggaaacatc atctgtcctt gattcagcct tggtgcctgc actctggggt acaaccacct   4920

cacagtagga tggtttttaa atggcccccc agttggggga gaagctaagg aaagagaagg   4980

ctgcagatcc aaagagtggc attgaagttt gctgggtgtc tgtaggtgga ccctttccag   5040

ctgggcagat agttgagggc tccctgggtt tgactgtatg tgcagacttt gataccaaaa   5100

tgttatgaaa agtcgtgatt cccgctgctc tttctggtac tggagggtgg gtaccttcag   5160

gctgtggggt ctctagcctg atattccatt gaaagggtgt gggataaagg tgctggggga   5220

aatgaggctc tgccacagcc atagagaggc cctcgggcag ttaagaaggg agcctggagc   5280

tgttttcatg agcagagata ctctcctgaa agcacccttc atagcttagc ccaggaaaaa   5340

taaaacaagg aagacaggtc actctcccct aggcagttcc tgttgtttct gttcctgacc   5400

ttgggcaggc agactgagaa gggactgtgt agggttttgt tttgtttttt ttcattttcc   5460

tttttatggc atgtgagagc atactgtaca ttctgtcctc tgtactaatg gaggaagggc   5520

agagagatta gttcaaggct aacattttat atcaggtaac tgaggcacac aaagggaaca   5580

aatgaagaac ataaaatgat cagtgtaaac ctgaaagcac gcagtcattg gcaagggaca   5640

ggctcatggg agctggtgag agagagcagt taaggcaagc accaggggaa agcagaccaa   5700

cttgaacaga tgtgatgcgg agaggttgga agaagcaaga aacctgaact catcatcagg   5760

ctattaaata aaatttatag gaggctgttg gtttggactg agctcctgca ataggcccaa   5820

cagaccaaaa caaaagggag tcactcatgt tgaagttctg tcttccagga aatcaggaga   5880

gagagagaga gaaagaatag ccaaatcccc aaacaggcca gttttaacca gcatgatgaa   5940

gtgtccttgg ttttaacctt tataaggaaa gcagctttga gatgaccagt ctggtttttg   6000

ttctttgtgt ctgctttcct cagccctttt ctgtctataa agccaacctc ctccgctcag   6060

ctcatgggaa cactcattct attttataga atgacatgtt gcccaattct agaatcaaaa   6120

ataaaggcca actaagatct tcaaagtaaa tttgttgtaa ttttatcttt tgagaagacc   6180

atatgggggc tgctgaaaag ttggtatctc aaataaagtc tgaagatcac ggctcagccc   6240

agattgttcc cctggccaac tccacaggtt tgaacctggc attctggaca ccagctatgc   6300

ctcctccatt tctcagaaaa cctttgatct tgtgtgtctt tcttcctact gaagggaatt   6360

gtgggggcag ttctttggcc ttcttgctga actttgctgg aaatagccca caatttttat   6420

cagaggttag aactgtacat tatcagagag actggacact ttatccccta gcaaagtggg   6480

agaagatttt accagctcat tccactccac cctggccttc ccccaccccc catccccagc   6540

agcatttcca tggaaatcca gatggtcgtg tagtgttatg gctctcttgt gatagactgg   6600

ccttcatatt ggagagctag ggagagcccc tgggagggag agagataagg cgctatctgc   6660

cttcaatcag aaccttcggt ttaaaatcat ctaagagtct atacttgtgt gtacatacgt   6720

atttattttt atttattttt atacaattcc attggcatgg tccttcaccg accctatgat   6780

ttgcactttt tatttctatg tgtgccacac acaatgcagt attaatggca accaggtaaa   6840

tattgattta ttttttaaag cttttcttca gtgttttgtc aaccatttca aagtgtctcc   6900

caaaaaagga tgctgaagag caattgctcc cttaagcaac agattcatat ttaccctggg   6960

ttaatacaac aaaaggcctg tataattgtc ttttcattgt taacacccaa aatagcatct   7020

atctagacag tatccccaaa gaatttggaa aatctgatgg tgtgagcagc agccgttagt   7080

atcagggttt cccattcttg gacagtccga ggctgtgacc tgttagataa ttagattata   7140

cttgaactgg accagagttt gttttttgaa tttatgagaa aaaccaaaac actaagttaa   7200

gtttgaactt gtaaagtatt gaaatttgtt gagtgtccta taaattgtca ctacttttcc   7260

tgatctgtat aactgactgc aaagtgtttg tttttacaaa agagaaaaga aaagattttt   7320

aataaagaga atttgaaagc tgtg                                          7344


<210>  7276
<211>  1283
<212>  PRT
<213>  Homo sapiens

<400>  7276

Met Trp Asp Gln Cys Gly Lys Val Leu Phe Met Trp Glu Gly Gly Pro 
1               5                   10                  15


Gln Ile Thr Lys Asn Ser Pro Leu Pro Pro Ser Leu Lys Thr Ser Cys 
            20                  25                  30


Ala Ser Arg Pro Leu Ser Ser His Ser Ala Ala Lys Leu Leu Asp Lys 
        35                  40                  45


Asn Pro Phe Ser Val Ser Asn Pro Asn Pro Leu Leu Pro Ser Pro Ala 
    50                  55                  60


Ser Leu Gln Leu Ala Gln Leu Gln Ala Gln Leu Thr Leu His Arg Leu 
65                  70                  75                  80


Lys Leu Ala Gln Thr Ala Val Thr Asn Asn Thr Ala Ala Ala Thr Val 
                85                  90                  95


Leu Asn Gln Val Leu Ser Lys Val Ala Met Ser Gln Pro Leu Phe Asn 
            100                 105                 110


Gln Leu Arg His Pro Ser Val Ile Thr Gly Pro His Gly His Ala Gly 
        115                 120                 125


Val Pro Gln His Ala Ala Ala Ile Pro Ser Thr Arg Phe Pro Ser Asn 
    130                 135                 140


Ala Ile Ala Phe Ser Pro Pro Ser Gln Thr Arg Gly Pro Gly Pro Ser 
145                 150                 155                 160


Met Asn Leu Pro Asn Gln Pro Pro Ser Ala Met Val Met His Pro Phe 
                165                 170                 175


Thr Gly Val Met Pro Gln Thr Pro Gly Gln Pro Ala Val Ile Leu Gly 
            180                 185                 190


Ile Gly Lys Thr Gly Pro Ala Pro Ala Thr Ala Gly Phe Tyr Glu Tyr 
        195                 200                 205


Gly Lys Ala Ser Ser Gly Gln Thr Tyr Gly Pro Glu Thr Asp Gly Gln 
    210                 215                 220


Pro Gly Phe Leu Pro Ser Ser Ala Ser Thr Ser Gly Ser Val Thr Tyr 
225                 230                 235                 240


Glu Gly His Tyr Ser His Thr Gly Gln Asp Gly Gln Ala Ala Phe Ser 
                245                 250                 255


Lys Asp Phe Tyr Gly Pro Asn Ser Gln Gly Ser His Val Ala Ser Gly 
            260                 265                 270


Phe Pro Ala Glu Gln Ala Gly Gly Leu Lys Ser Glu Val Gly Pro Leu 
        275                 280                 285


Leu Gln Gly Thr Asn Ser Gln Trp Glu Ser Pro His Gly Phe Ser Gly 
    290                 295                 300


Gln Ser Lys Pro Asp Leu Thr Ala Gly Pro Met Trp Pro Pro Pro His 
305                 310                 315                 320


Asn Gln Pro Tyr Glu Leu Tyr Asp Pro Glu Glu Pro Thr Ser Asp Arg 
                325                 330                 335


Thr Pro Pro Ser Phe Gly Gly Arg Leu Asn Asn Ser Lys Gln Gly Phe 
            340                 345                 350


Ile Gly Ala Gly Arg Arg Ala Lys Glu Asp Gln Ala Leu Leu Ser Val 
        355                 360                 365


Arg Pro Leu Gln Ala His Glu Leu Asn Asp Phe His Gly Val Ala Pro 
    370                 375                 380


Leu His Leu Pro His Ile Cys Ser Ile Cys Asp Lys Lys Val Phe Asp 
385                 390                 395                 400


Leu Lys Asp Trp Glu Leu His Val Lys Gly Lys Leu His Ala Gln Lys 
                405                 410                 415


Cys Leu Val Phe Ser Glu Lys Ser Arg Phe Pro Phe Leu Ala Leu Ser 
            420                 425                 430


Ser Ala Gly Ile Arg Cys Ile Leu Gly Ser Ala Glu Gly Thr Leu Cys 
        435                 440                 445


Ala Ser Pro Asn Ser Thr Ala Val Tyr Asn Pro Ala Gly Asn Glu Gly 
    450                 455                 460


Glu Gln Gly Pro Thr Gly Gln Gln Leu Glu Ala Glu Val Gly Tyr Pro 
465                 470                 475                 480


Gln Ala His Tyr Val Leu Ser Leu Ile Thr Arg Thr Ser Leu Met Ser 
                485                 490                 495


Pro Ser His Gly Cys Arg Lys Gln Thr Asp Pro Lys Thr Leu Lys Cys 
            500                 505                 510


Ile Gly Pro Ala Val Trp Ala His Gln Tyr Ser Leu Arg Tyr Leu Arg 
        515                 520                 525


Arg Lys Ala Leu Leu Ile Ile Ser Met Ser Arg Val Ser Arg Asp Val 
    530                 535                 540


Glu Ala Ala Lys Gln Val Asn Arg Pro Arg Ser Val Gly Asn Pro Met 
545                 550                 555                 560


Asp Leu Pro Val Lys Phe Ala Gln Arg Lys Gly Ala Gly Arg Val Val 
                565                 570                 575


His Ile Cys Asn Leu Pro Glu Gly Ser Cys Thr Glu Asn Asp Val Ile 
            580                 585                 590


Asn Leu Gly Leu Pro Phe Gly Lys Val Thr Asn Tyr Ile Leu Met Lys 
        595                 600                 605


Ser Thr Asn Gln Ala Phe Leu Glu Met Ala Tyr Thr Glu Ala Ala Gln 
    610                 615                 620


Ala Met Val Gln Tyr Tyr Gln Glu Lys Ser Ala Val Ile Asn Gly Glu 
625                 630                 635                 640


Lys Leu Leu Ile Arg Met Ser Lys Arg Tyr Lys Glu Leu Gln Leu Lys 
                645                 650                 655


Lys Pro Gly Lys Ala Val Ala Ala Ile Ile Gln Asp Ile His Ser Gln 
            660                 665                 670


Arg Glu Arg Asp Met Phe Arg Glu Ala Asp Arg Tyr Gly Pro Glu Arg 
        675                 680                 685


Pro Arg Ser Arg Ser Pro Val Ser Arg Ser Leu Ser Pro Arg Ser His 
    690                 695                 700


Thr Pro Ser Phe Thr Ser Cys Ser Ser Ser His Ser Pro Pro Gly Pro 
705                 710                 715                 720


Ser Arg Ala Asp Trp Gly Asn Gly Arg Asp Ser Trp Glu His Ser Pro 
                725                 730                 735


Tyr Ala Arg Arg Glu Glu Glu Arg Asp Pro Ala Pro Trp Arg Asp Asn 
            740                 745                 750


Gly Asp Asp Lys Arg Asp Arg Met Asp Pro Trp Ala His Asp Arg Lys 
        755                 760                 765


His His Pro Arg Gln Leu Asp Lys Ala Glu Leu Asp Glu Arg Pro Glu 
    770                 775                 780


Gly Gly Arg Pro His Arg Glu Lys Tyr Pro Arg Ser Gly Ser Pro Asn 
785                 790                 795                 800


Leu Pro His Ser Val Ser Ser Tyr Lys Ser Arg Glu Asp Gly Tyr Tyr 
                805                 810                 815


Arg Lys Glu Pro Lys Ala Lys Trp Asp Lys Tyr Leu Lys Gln Gln Gln 
            820                 825                 830


Asp Ala Pro Gly Arg Ser Arg Arg Lys Asp Glu Ala Arg Leu Arg Glu 
        835                 840                 845


Ser Arg His Pro His Pro Asp Asp Ser Gly Lys Glu Asp Gly Leu Gly 
    850                 855                 860


Pro Lys Val Thr Arg Ala Pro Glu Gly Ala Lys Ala Lys Gln Asn Glu 
865                 870                 875                 880


Lys Asn Lys Thr Lys Arg Thr Asp Arg Asp Gln Glu Gly Ala Asp Asp 
                885                 890                 895


Arg Lys Glu Asn Thr Met Ala Glu Asn Glu Ala Gly Lys Glu Glu Gln 
            900                 905                 910


Glu Gly Met Glu Glu Ser Pro Gln Ser Val Gly Arg Gln Glu Lys Glu 
        915                 920                 925


Ala Glu Phe Ser Asp Pro Glu Asn Thr Arg Thr Lys Lys Glu Gln Asp 
    930                 935                 940


Trp Glu Ser Glu Ser Glu Ala Glu Gly Glu Ser Trp Tyr Pro Thr Asn 
945                 950                 955                 960


Met Glu Glu Leu Val Thr Val Asp Glu Val Gly Glu Glu Glu Asp Phe 
                965                 970                 975


Ile Val Glu Pro Asp Ile Pro Glu Leu Glu Glu Ile Val Pro Ile Asp 
            980                 985                 990


Gln Lys Asp Lys Ile Cys Pro Glu Thr Cys Leu Cys Val Thr Thr Thr 
        995                 1000                1005


Leu Asp Leu Asp Leu Ala Gln Asp Phe Pro Lys Glu Gly Val Lys Ala 
    1010                1015                1020


Val Gly Asn Gly Ala Ala Glu Ile Ser Leu Lys Ser Pro Arg Glu Leu 
1025                1030                1035                1040


Pro Ser Ala Ser Thr Ser Cys Pro Ser Asp Met Asp Val Glu Met Pro 
                1045                1050                1055


Gly Leu Asn Leu Asp Ala Glu Arg Lys Pro Ala Glu Ser Glu Thr Gly 
            1060                1065                1070


Leu Ser Leu Glu Asp Ser Asp Cys Tyr Glu Lys Glu Ala Lys Gly Val 
        1075                1080                1085


Glu Ser Ser Asp Val His Pro Ala Pro Thr Val Gln Gln Met Ser Ser 
    1090                1095                1100


Pro Lys Pro Ala Glu Glu Arg Ala Arg Gln Pro Ser Pro Phe Val Asp 
1105                1110                1115                1120


Asp Cys Lys Thr Arg Gly Thr Pro Glu Asp Gly Ala Cys Glu Gly Ser 
                1125                1130                1135


Pro Leu Glu Glu Lys Ala Ser Pro Pro Ile Glu Thr Asp Leu Gln Asn 
            1140                1145                1150


Gln Ala Cys Gln Glu Val Leu Thr Pro Glu Asn Ser Arg Tyr Val Glu 
        1155                1160                1165


Met Lys Ser Leu Glu Val Arg Ser Pro Glu Tyr Thr Glu Val Glu Leu 
    1170                1175                1180


Lys Gln Pro Leu Ser Leu Pro Ser Trp Glu Pro Glu Asp Val Phe Ser 
1185                1190                1195                1200


Glu Leu Ser Ile Pro Leu Gly Val Glu Phe Val Val Pro Arg Thr Gly 
                1205                1210                1215


Phe Tyr Cys Lys Leu Cys Gly Leu Phe Tyr Thr Ser Glu Glu Thr Ala 
            1220                1225                1230


Lys Met Ser His Cys Arg Ser Ala Val His Tyr Arg Asn Leu Gln Lys 
        1235                1240                1245


Tyr Leu Ser Gln Leu Ala Glu Glu Gly Leu Lys Glu Thr Glu Gly Ala 
    1250                1255                1260


Asp Ser Pro Arg Pro Glu Asp Ser Gly Ile Val Pro Arg Phe Glu Arg 
1265                1270                1275                1280


Lys Lys Leu 



<210>  7277
<211>  566
<212>  DNA
<213>  Homo sapiens

<400>  7277
acagtccagc aaatgtcttc ccctaagcca gcagaggaga gggcccggca gccaagccca     60

tttgtggatg attgcaagac cagggggacc cccgaagatg gggcttgtga aggcagcccc    120

ctggaggaga aagccagccc ccccatcgaa actgacctcc aaaaccaagc ttgccaagaa    180

gtgttgaccc cggaaaactc caggtacgtg gaaatgaaat ctctggaggt gaggtcacca    240

gagtacactg aagtggaact gaaacagccc ctttctttgc cctcttggga accagaggat    300

gtgttcagtg aacttagcat tcctctaggg gtggagttcg tggttcccag gactggcttt    360

tattgcaagc tgtgtgggct gttctacacg agcgaggaga cagcaaagat gagccactgc    420

cgcagcgctg tccactacag gaacttacag atggagtttc actcttgttg cccaggctgg    480

attgcaacgg tgcgatctcg gttcacagca acctccgcct cccgggttca agtgattctc    540

ctgcctcagc ctcccgagta gctggg                                         566


<210>  7278
<211>  182
<212>  PRT
<213>  Homo sapiens

<400>  7278

Met Ser Ser Pro Lys Pro Ala Glu Glu Arg Ala Arg Gln Pro Ser Pro 
1               5                   10                  15


Phe Val Asp Asp Cys Lys Thr Arg Gly Thr Pro Glu Asp Gly Ala Cys 
            20                  25                  30


Glu Gly Ser Pro Leu Glu Glu Lys Ala Ser Pro Pro Ile Glu Thr Asp 
        35                  40                  45


Leu Gln Asn Gln Ala Cys Gln Glu Val Leu Thr Pro Glu Asn Ser Arg 
    50                  55                  60


Tyr Val Glu Met Lys Ser Leu Glu Val Arg Ser Pro Glu Tyr Thr Glu 
65                  70                  75                  80


Val Glu Leu Lys Gln Pro Leu Ser Leu Pro Ser Trp Glu Pro Glu Asp 
                85                  90                  95


Val Phe Ser Glu Leu Ser Ile Pro Leu Gly Val Glu Phe Val Val Pro 
            100                 105                 110


Arg Thr Gly Phe Tyr Cys Lys Leu Cys Gly Leu Phe Tyr Thr Ser Glu 
        115                 120                 125


Glu Thr Ala Lys Met Ser His Cys Arg Ser Ala Val His Tyr Arg Asn 
    130                 135                 140


Leu Gln Met Glu Phe His Ser Cys Cys Pro Gly Trp Ile Ala Thr Val 
145                 150                 155                 160


Arg Ser Arg Phe Thr Ala Thr Ser Ala Ser Arg Val Gln Val Ile Leu 
                165                 170                 175


Leu Pro Gln Pro Pro Glu 
            180


<210>  7279
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  7279
acctattatg gctcctctca ccggggctgc ataacccttt agcctgcagg actggtcact     60

actggcatgg agacttctag ggaggggtgg agttcgtggt tcccaggact ggcttttatt    120

gcaagctgtg tgggctgttc tacacgagcg aggagacagc aaagatgagc cactgccgca    180

gcgctgtcca ctacaggaac ttacagaaat atttgtccca gctggccgag gagggcctca    240

aggagaccga gggggcagat agcccgaggc cagaggacag cggaatcgtg ccacgcttcg    300

aaaggaaaaa gctctgatgc ttctgcttct gctgctactg ctgctgctgc aaggttggaa    360

aggagagctt gctgaagtgg ggccttcctg attctgggga caggactaaa gcctgagagg    420

aaggaaaacc aagcagggca cattgcttgg gcttgttccc agagactcag tgaaatgccc    480

ctgatatgtc tccaggagca agtcacccag gtgtgtccag cccactgagg gtcaccaact    540

ctctccctgc tgactcttgt ttctctcaat ctt                                 573


<210>  7280
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  7280

Met Ser His Cys Arg Ser Ala Val His Tyr Arg Asn Leu Gln Lys Tyr 
1               5                   10                  15


Leu Ser Gln Leu Ala Glu Glu Gly Leu Lys Glu Thr Glu Gly Ala Asp 
            20                  25                  30


Ser Pro Arg Pro Glu Asp Ser Gly Ile Val Pro Arg Phe Glu Arg Lys 
        35                  40                  45


Lys Leu 
    50


<210>  7281
<211>  892
<212>  DNA
<213>  Homo sapiens

<400>  7281
aaaacagagt tgttttggga gttaaatgag cttatttaag tcaagcagtt agaacagcac     60

ttgacactag ataagggctt tggaagtgtt tgctattata gctgtacttt ctactctttc    120

ttttcttttc tttttttctt ttttttttct tttttttttt tttagatgga gtttcactct    180

tgttgcccag gctggattgc aacggtgcga tctcggttca cagcaacctc cgcctcccgg    240

gttcaagtga ttctcctgcc tcagcctccc gagtagctgg gattacaggc atgtgccacc    300

acacccagct aattttttgt attttaatta gagacggggt ttctccatgt tggtcaggct    360

ggtctcaact cccgacctca ggtgatccac ccacctcggc ctcccaagtg ctgggattac    420

aggtgtgaga caccacgctc ggcctgtact ttctacattt tctacaggag acatgtatta    480

cttgcaagct aacataatga gaaatatttg tcccagctgg ccgaggaggg cctcaaggag    540

accgaggggg cagatagccc gaggccagag gacagcggaa tcgtgccacg cttcgaaagg    600

aaaaagctct gatgcttctg cttctgctgc tactgctgct gctgcaaggt tggaaaggag    660

agcttgctga agtggggcct tcctgattct ggggacagga ctaaagcctg agaggaagga    720

aaaccaagca gggcacattg cttgggcttg ttcccagaga ctcagtgaaa tgcccctgat    780

atgtctccag gagcaagtca cccaggtgtg tccagcccac tgagggtcac caactctctc    840

cctgctgact cttgtttctc tcaatctttc aattcgtttt tctctctttt cc            892


<210>  7282
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  7282

Met Tyr Tyr Leu Gln Ala Asn Ile Met Arg Asn Ile Cys Pro Ser Trp 
1               5                   10                  15


Pro Arg Arg Ala Ser Arg Arg Pro Arg Gly Gln Ile Ala Arg Gly Gln 
            20                  25                  30


Arg Thr Ala Glu Ser Cys His Ala Ser Lys Gly Lys Ser Ser Asp Ala 
        35                  40                  45


Ser Ala Ser Ala Ala Thr Ala Ala Ala Ala Arg Leu Glu Arg Arg Ala 
    50                  55                  60


Cys 
65


<210>  7283
<211>  1826
<212>  DNA
<213>  Homo sapiens

<400>  7283
ggctccggga gggggcgggc ccgcgccgac acgctccagg ctgggctcag aaagagggaa     60

ccaggccgga tgcccgcagt ccggggcgtt ggggagggcg cggctggacc tgcggggcta    120

caagaaggca gccggacccc cgcaccgcag gcccggacct gacaggaccg cgacccccac    180

gcctccgccc ccgccccctc ccatcttgcg gctgcctccg aggagggatg ggggagaggg    240

cgcagtcttc ccgagcgtgt gagccgcgcc tactgggttt catcatgttg tccaggctgg    300

tcttgaactc ctgggctcaa gcaatcagcc cacctctgcc tcccaaagcg ttgagattac    360

aagcgtgagc caccattcct ggaccctcgt agtttttctg gagcctcgtg atttgatatg    420

atcttcctgc cgctgattcc tcacagtgtt ggcttgccac acctccaggg gcactgatca    480

cattctacct ggcattattt catctgagtc cctgtcctag cccttctgcc cattagactg    540

taaccttgtt tagggaaaga cctgtgtctt actcatctgt gattttgttg ttgttgttgt    600

tttgagacag ggtcttgccc tgttgcccag gctggagagc agtggtgcaa tcttggctca    660

ctgcagcctc aacctgttgg ggtcaagcca tcctcccacc tcagctttcc aagtagctga    720

gactacaggc ctgtgccacc acacccagct agttttttgt atttttagta gagatggggt    780

tttgccatgt tgcccaggct tctcttgaac tcctgagctc aagggatctg cctgcctcgg    840

cctcccaaag tgctgggatt acaggcgtga gccactgtgc ctgacccact cacctgtcat    900

tgtagtactt aagatgcctt gttcatttat tgtgcctgtg caataaatac accttgattt    960

gagtttacaa agattctcag cagttggtgg tcatcctcat ctcctgggcg ggggcctcct   1020

ggtgtggcca gtatctgaat tagtctcata actcatgttc actttttaaa atcggagctt   1080

cccagacctc agttttgttt tgttattttc cattatctgc agctgtctcc tttcccctct   1140

ctcacctata ctctactgat cagtgactgc tggctccttt gttacccatc cttctctttc   1200

tccacatttt ttctcttctc atccctttca gttctggact gtttccttct tcctccctgt   1260

ctttcattta gtcattcatt gaatgtactt actaagcaca tatagcataa tcaggctgtg   1320

ttgggtaggc atcccgagtt ctatgagata aagaaagaat gggatatgat taccaatttt   1380

aagaagcatc taaaacaacc tgttatgttt tagcaaattg cccccaaagg acccattagg   1440

gaggaaaacg ttcatgtcct ttttgcgtat catctcaagc agtacccatg atggctggga   1500

tcccagaacc cacctttgag aatgctgccg tatttgcgtg tggttgacaa ggttgggcca   1560

gacactcagg aaatagggtt gtcgtcctac ctcccccact aacttcctgt aagaacttca   1620

gcccctctca ggaccttttt ctttaccaat aaaattcaga aattgggctc aatcagtaat   1680

tcccaagtta ttttccaaag aacatgaatt ttgtggaact ttaatagata tcatgcaaaa   1740

aaaaatgtgg gagggattgt tccatggtca aatggtcttg gaaataactc gtttaaacaa   1800

aaataaaact gtttctttac ccacaa                                        1826


<210>  7284
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  7284

Met Gly Glu Arg Ala Gln Ser Ser Arg Ala Cys Glu Pro Arg Leu Leu 
1               5                   10                  15


Gly Phe Ile Met Leu Ser Arg Leu Val Leu Asn Ser Trp Ala Gln Ala 
            20                  25                  30


Ile Ser Pro Pro Leu Pro Pro Lys Ala Leu Arg Leu Gln Ala 
        35                  40                  45


<210>  7285
<211>  395
<212>  DNA
<213>  Homo sapiens

<400>  7285
cattctcctc acagggcgtt ctgcaaactc ggctgaagca aaggttttga gcttcctgat     60

ggtccctgcc tccatttcta gaaactgctt aggcgaacac tccaagtgat cagcctgtcc    120

gattcctcct ccctctggcc gctgctttct ctgtggcttc cagtttctgg agatcccatg    180

ctaagaagtt tctctcagcg aatcccctca aacctttgag atggaaataa ttcccatttc    240

acagatataa agcaggctcc aaaactcttt gaagttcctt tgctaatcat gactagccaa    300

gccttgtgcc tgacccactc acctgtcatt gtagtactta agatgccttg ttcatttatt    360

gtgcctgtgc aataaataca ccttgatttg agttt                               395


<210>  7286
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  7286

Ala Asn Thr Pro Ser Asp Gln Pro Val Arg Phe Leu Leu Pro Leu Ala 
1               5                   10                  15


Ala Ala Phe Ser Val Ala Ser Ser Phe Trp Arg Ser His Ala Lys Lys 
            20                  25                  30


Phe Leu Ser Ala Asn Pro Leu Lys Pro Leu Arg Trp Lys 
        35                  40                  45


<210>  7287
<211>  723
<212>  DNA
<213>  Homo sapiens

<400>  7287
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

agg                                                                  723


<210>  7288
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  7288

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp 
145


<210>  7289
<211>  869
<212>  DNA
<213>  Homo sapiens

<400>  7289
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatg                                      869


<210>  7290
<211>  195
<212>  PRT
<213>  Homo sapiens

<400>  7290

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu 
        195


<210>  7291
<211>  1156
<212>  DNA
<213>  Homo sapiens

<400>  7291
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctag                                                   1156


<210>  7292
<211>  290
<212>  PRT
<213>  Homo sapiens

<400>  7292

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln 
    290


<210>  7293
<211>  2149
<212>  DNA
<213>  Homo sapiens

<400>  7293
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctagagct gctctggata aggctaccgt gcttctgagt atgtctaaag   1200

gtggaaagcg taaagatagt gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc   1260

ttgttaaaga gattgatatg ctgctgaaag aatatttact ctctggagac atatctgaag   1320

ctgaacattg ccttaaggaa ctggaagtac ctcattttca ccatgagctt gtatatgaag   1380

ctattataat ggttttagag tcaactggag aaagtacatt taagatgatt ttggatttat   1440

taaagtccct ttggaagtct tctaccatta ctgtagacca aatgaaaaga ggttatgaga   1500

gaatttacaa tgaaattccg gacattaatc tggatgtccc acattcatac tctgtgctgg   1560

agcggtttgt agaagaatgt tttcaggctg gaataatttc caaacaactc agagatcttt   1620

gtccttcaag gggcagaaag cgttttgtaa gcgaaggaga tggaggtcgt cttaaaccag   1680

agagctactg aatataagaa ctcttgcagt cttagatgtt ataaaaatat atatctgaat   1740

tgtaagagtt gttagcacaa gttttttttt tttttttttt taagcacttg ttttgggtac   1800

aaggcatttc tgacatttta taaacctaca tttaagggga atttttaaag gaaatgtttt   1860

ttcttttttt tttgtttttc gagggggcaa ggagggacag aaaagtaacc tcttcttaag   1920

tggaatattc taataagcta ccttttgtaa gtgccatgtt tattatctaa tcattccaag   1980

ttttgcattg atgtctgact gccactcctt tctttcaagg acagtgtttt ttgtagtaaa   2040

atcactggtt tatacaaagc tttatttagg gggtaaagtt aagctgctaa aaccccatgt   2100

tggctgctgc tgttgagata ctgtgctttg ggagtaaaaa aagaaagtt               2149


<210>  7294
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  7294

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val Leu Leu Ser Met 
    290                 295                 300


Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly Gly 
305                 310                 315                 320


Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu Lys 
                325                 330                 335


Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys 
            340                 345                 350


Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile 
        355                 360                 365


Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu 
    370                 375                 380


Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln 
385                 390                 395                 400


Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn 
                405                 410                 415


Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu 
            420                 425                 430


Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro 
        435                 440                 445


Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu 
    450                 455                 460


Lys Pro Glu Ser Tyr 
465


<210>  7295
<211>  2352
<212>  DNA
<213>  Homo sapiens

<400>  7295
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctagagct gctctggata aggctaccgt gcttctgagt atgtctaaag   1200

gtggaaagcg taaagatagt gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc   1260

ttgttaaaga gattgatatg ctgctgaaag aatatttact ctctggagac atatctgaag   1320

ctgaacattg ccttaaggaa ctggaagtac ctcattttca ccatgagctt gtatatgaag   1380

ctattataat ggttttagag tcaactggag aaagtacatt taagatgatt ttggatttat   1440

taaagtccct ttggaagtct tctaccatta ctgtagacca aatgaaaaga ggttatgaga   1500

gaatttacaa tgaaattccg gacattaatc tggatgtccc acattcatac tctgtgctgg   1560

agcggtttgt agaagaatgt tttcaggctg gaataatttc caaacaactc agagatcttt   1620

gtccttcaag gggcagaaag cgttttgtaa gcgaaggaga tggaggtcgt cttaaaccag   1680

agagctactg aatataagaa ctcttgcagt cttagatgtt ataaaaatat atatctgaat   1740

tgtaagagtt gttagcacaa gttttttttt tttttttttt taagcacttg ttttgggtac   1800

aaggcatttc tgacatttta taaacctaca tttaagggga atttttaaag gaaatgtttt   1860

ttcttttttt tttgtttttc gagggggcaa ggagggacag aaaagtaacc tcttcttaag   1920

tggaatattc taataagcta ccttttgtaa gtgccatgtt tattatctaa tcattccaag   1980

ttttgcattg atgtctgact gccactcctt tctttcaagg acagtgtttt ttgtagtaaa   2040

atcactggtt tatacaaagc tttatttagg gggtaaagtt aagctgctaa aaccccatgt   2100

tggctgctgc tgttgagata ctgtgctttg ggagtaaaaa aagaaagtta tttctttgtc   2160

ttaaagaatt tttaaaaaat tagtcatgag acttattcat ctttccaggg aacatactga   2220

ttggtcttaa aagactagac agttaagtaa aaggtggctg gaacatctat ttttctacaa   2280

aactggaaaa atgaacctgg ttctagaaga atgtacacca aaataaaaca tgtgaagcag   2340

tattgattct tt                                                       2352


<210>  7296
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  7296

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val Leu Leu Ser Met 
    290                 295                 300


Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly Gly 
305                 310                 315                 320


Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu Lys 
                325                 330                 335


Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys 
            340                 345                 350


Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile 
        355                 360                 365


Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu 
    370                 375                 380


Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln 
385                 390                 395                 400


Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn 
                405                 410                 415


Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu 
            420                 425                 430


Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro 
        435                 440                 445


Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu 
    450                 455                 460


Lys Pro Glu Ser Tyr 
465


<210>  7297
<211>  2748
<212>  DNA
<213>  Homo sapiens

<400>  7297
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctagagct gctctggata aggctaccgt gcttctgagt atgtctaaag   1200

gtggaaagcg taaagatagt gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc   1260

ttgttaaaga gattgatatg ctgctgaaag aatatttact ctctggagac atatctgaag   1320

ctgaacattg ccttaaggaa ctggaagtac ctcattttca ccatgagctt gtatatgaag   1380

ctattataat ggttttagag tcaactggag aaagtacatt taagatgatt ttggatttat   1440

taaagtccct ttggaagtct tctaccatta ctgtagacca aatgaaaaga ggttatgaga   1500

gaatttacaa tgaaattccg gacattaatc tggatgtccc acattcatac tctgtgctgg   1560

agcggtttgt agaagaatgt tttcaggctg gaataatttc caaacaactc agagatcttt   1620

gtccttcaag gggcagaaag cgttttgtaa gcgaaggaga tggaggtcgt cttaaaccag   1680

agagctactg aatataagaa ctcttgcagt cttagatgtt ataaaaatat atatctgaat   1740

tgtaagagtt gttagcacaa gttttttttt tttttttttt taagcacttg ttttgggtac   1800

aaggcatttc tgacatttta taaacctaca tttaagggga atttttaaag gaaatgtttt   1860

ttcttttttt tttgtttttc gagggggcaa ggagggacag aaaagtaacc tcttcttaag   1920

tggaatattc taataagcta ccttttgtaa gtgccatgtt tattatctaa tcattccaag   1980

ttttgcattg atgtctgact gccactcctt tctttcaagg acagtgtttt ttgtagtaaa   2040

atcactggtt tatacaaagc tttatttagg gggtaaagtt aagctgctaa aaccccatgt   2100

tggctgctgc tgttgagata ctgtgctttg ggagtaaaaa aagaaagtta tttctttgtc   2160

ttaaagaatt tttaaaaaat tagtcatgag acttattcat ctttccaggg aacatactga   2220

ttggtcttaa aagactagac agttaagtaa aaggtggctg gaacatctat ttttctacaa   2280

aactggaaaa atgaacctgg ttctagaaga atgtacacca aaataaaaca tgtgaagcag   2340

tattgattct ttattgggag tacatttttt taggtctctt aaactttaat ttcacacagt   2400

aaattttgaa tctcataagg aagcatattt gaacctagtc aatttaatct tagtgttccc   2460

ttgaaaactt tttttcccta caaaatttta agtgaaaaat acaatagtaa attaagatta   2520

cactggggaa aaaaatgcag gtatcacttt actccattgt tatctgacct agagcttaat   2580

taagttttag aaatatgtaa taccttccat cattccatca tccttaaatt ctgttaccaa   2640

ataatggcta atgttacaaa aagttatact ccagagaccc aaagcttgac atttacctaa   2700

tgtatgagaa aatattacca attaacaata aagaatgatc atattttt                2748


<210>  7298
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  7298

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val Leu Leu Ser Met 
    290                 295                 300


Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly Gly 
305                 310                 315                 320


Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu Lys 
                325                 330                 335


Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys 
            340                 345                 350


Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile 
        355                 360                 365


Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu 
    370                 375                 380


Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln 
385                 390                 395                 400


Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn 
                405                 410                 415


Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu 
            420                 425                 430


Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro 
        435                 440                 445


Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu 
    450                 455                 460


Lys Pro Glu Ser Tyr 
465


<210>  7299
<211>  3608
<212>  DNA
<213>  Homo sapiens

<400>  7299
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctagagct gctctggata aggctaccgt gcttctgagt atgtctaaag   1200

gtggaaagcg taaagatagt gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc   1260

ttgttaaaga gattgatatg ctgctgaaag aatatttact ctctggagac atatctgaag   1320

ctgaacattg ccttaaggaa ctggaagtac ctcattttca ccatgagctt gtatatgaag   1380

ctattataat ggttttagag tcaactggag aaagtacatt taagatgatt ttggatttat   1440

taaagtccct ttggaagtct tctaccatta ctgtagacca aatgaaaaga ggttatgaga   1500

gaatttacaa tgaaattccg gacattaatc tggatgtccc acattcatac tctgtgctgg   1560

agcggtttgt agaagaatgt tttcaggctg gaataatttc caaacaactc agagatcttt   1620

gtccttcaag gggcagaaag cgttttgtaa gcgaaggaga tggaggtcgt cttaaaccag   1680

agagctactg aatataagaa ctcttgcagt cttagatgtt ataaaaatat atatctgaat   1740

tgtaagagtt gttagcacaa gttttttttt tttttttttt taagcacttg ttttgggtac   1800

aaggcatttc tgacatttta taaacctaca tttaagggga atttttaaag gaaatgtttt   1860

ttcttttttt tttgtttttc gagggggcaa ggagggacag aaaagtaacc tcttcttaag   1920

tggaatattc taataagcta ccttttgtaa gtgccatgtt tattatctaa tcattccaag   1980

ttttgcattg atgtctgact gccactcctt tctttcaagg acagtgtttt ttgtagtaaa   2040

atcactggtt tatacaaagc tttatttagg gggtaaagtt aagctgctaa aaccccatgt   2100

tggctgctgc tgttgagata ctgtgctttg ggagtaaaaa aagaaagtta tttctttgtc   2160

ttaaagaatt tttaaaaaat tagtcatgag acttattcat ctttccaggg aacatactga   2220

ttggtcttaa aagactagac agttaagtaa aaggtggctg gaacatctat ttttctacaa   2280

aactggaaaa atgaacctgg ttctagaaga atgtacacca aaataaaaca tgtgaagcag   2340

tattgattct ttattgggag tacatttttt taggtctctt aaactttaat ttcacacagt   2400

aaattttgaa tctcataagg aagcatattt gaacctagtc aatttaatct tagtgttccc   2460

ttgaaaactt tttttcccta caaaatttta agtgaaaaat acaatagtaa attaagatta   2520

cactggggaa aaaaatgcag gtatcacttt actccattgt tatctgacct agagcttaat   2580

taagttttag aaatatgtaa taccttccat cattccatca tccttaaatt ctgttaccaa   2640

ataatggcta atgttacaaa aagttatact ccagagaccc aaagcttgac atttacctaa   2700

tgtatgagaa aatattacca attaacaata aagaatgatc atatttttaa cctcttttac   2760

atagcctaat aactcagcaa ggcctcaacg tctgtgctaa tttaaactgc caaatattga   2820

ctgcagcaaa caagaattat attcagaatt tatgagggta ctgttaggag tatactgctt   2880

acaggtttag atatagtctg ttagaattaa aaccaagttt agtgttcata tttacctcat   2940

gggctttatc aagcccatat tacctcagct tatatatagt taccattttt aggtttttaa   3000

ttgtttgaca cttggatgat aaatgcagtc attttattct caagtgctta aaattaatgt   3060

aattaaaagc ttagctgact acagaatagg tgagggtttc ttaaaaatga gatttaaggg   3120

ctgggcacgg tggctcatgc ctgtaatccc agcactttgg gaggccgagg tgggcggatc   3180

acttgaggtt gggagttcat gaccagcttg accaacatga agaaaccctg tctctattaa   3240

aaatacaaaa gtagccaggc atggtggcgc atgcgtgtaa tcccagctac ttgggaggct   3300

gaggcaggag aattgcttga acctgggagg cagaggttgc agtgagtcga gatggtgcca   3360

ttgctctcgt ttgggcaaca agagtgaaac tcttgtctca aaaaaaaaaa aaaatgaggt   3420

ttaagacagt tttgtcatta ctggtgggat ctggtcacac aagatagcat taaacgtgac   3480

atggcacata aaattggtta aaaaattttg ttttttaatt acgtaatgta aaagcccaac   3540

aaacacttta tgcaagattg gaatgtatct tcaaattcag atttaataaa catgtaaaga   3600

tcctctgt                                                            3608


<210>  7300
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  7300

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val Leu Leu Ser Met 
    290                 295                 300


Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly Gly 
305                 310                 315                 320


Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu Lys 
                325                 330                 335


Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys 
            340                 345                 350


Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile 
        355                 360                 365


Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu 
    370                 375                 380


Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln 
385                 390                 395                 400


Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn 
                405                 410                 415


Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu 
            420                 425                 430


Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro 
        435                 440                 445


Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu 
    450                 455                 460


Lys Pro Glu Ser Tyr 
465


<210>  7301
<211>  3631
<212>  DNA
<213>  Homo sapiens

<400>  7301
cctcctcagc tccggctccg ccgccacgat tggccagccg accacccggc ctcggccaat     60

aagcgccgcc ctctcgcccc cgtgttactg ggtagaagaa aacaaaaaca aacagagcga    120

gaagggccag agactctccg aggcggcggc agagacagaa gagcggggtc ggggccggct    180

gaccaggaac ctgggcgagc agcggcgggg gcccgaggga ttctgaagga agatttccat    240

taggtaattt gtttaatcag tgcaagcgaa attaagggaa aatggatgta gaaaatgagc    300

agatactgaa tgtaaaccct gcagatcctg ataacttaag tgactctctc ttttccggtg    360

atgaagaaaa tgctgggact gaggaaataa agaatgaaat aaatggaaat tggatttcag    420

catcctccat taacgaagct agaattaatg ccaaggcaaa aaggcgacta aggaaaaact    480

catcccggga ctctggcaga ggcgattcgg tcagcgacag tgggagtgac gcccttagaa    540

gtggattaac tgtgccaacc agtccaaagg gaaggttgct ggataggcga tccagatctg    600

ggaaaggaag gggactacca aagaaaggtg gtgcaggagg caaaggtgtc tggggtacac    660

ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga tcctaactat gatgatgacc    720

aggagaactg tgtttatgaa actgtagttt tgcctttgga tgaaagggca tttgagaaga    780

ctttaacacc aatcatacag gaatattttg agcatggaga tactaatgaa gttgcggaaa    840

tgttaagaga tttaaatctt ggtgaaatga aaagtggagt accagtgttg gcagtatcct    900

tagcattgga ggggaaggct agtcatagag agatgacatc taagcttctt tctgaccttt    960

gtgggacagt aatgagcaca actgatgtgg aaaaatcatt tgataaattg ttgaaagatc   1020

tacctgaatt agcactggat actcctagag caccacagtt ggtgggccag tttattgcta   1080

gagctgttgg agatggaatt ttatgtaata cctatattga tagttacaaa ggaactgtag   1140

attgtgtgca ggctagagct gctctggata aggctaccgt gcttctgagt atgtctaaag   1200

gtggaaagcg taaagatagt gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc   1260

ttgttaaaga gattgatatg ctgctgaaag aatatttact ctctggagac atatctgaag   1320

ctgaacattg ccttaaggaa ctggaagtac ctcattttca ccatgagctt gtatatgaag   1380

ctattataat ggttttagag tcaactggag aaagtacatt taagatgatt ttggatttat   1440

taaagtccct ttggaagtct tctaccatta ctgtagacca aatgaaaaga ggttatgaga   1500

gaatttacaa tgaaattccg gacattaatc tggatgtccc acattcatac tctgtgctgg   1560

agcggtttgt agaagaatgt tttcaggctg gaataatttc caaacaactc agagatcttt   1620

gtccttcaag gggcagaaag cgttttgtaa gcgaaggaga tggaggtcgt cttaaaccag   1680

agagctactg aatataagaa ctcttgcagt cttagatgtt ataaaaatat atatctgaat   1740

tgtaagagtt gttagcacaa gttttttttt tttttttttt taagcacttg ttttgggtac   1800

aaggcatttc tgacatttta taaacctaca tttaagggga atttttaaag gaaatgtttt   1860

ttcttttttt tttgtttttc gagggggcaa ggagggacag aaaagtaacc tcttcttaag   1920

tggaatattc taataagcta ccttttgtaa gtgccatgtt tattatctaa tcattccaag   1980

ttttgcattg atgtctgact gccactcctt tctttcaagg acagtgtttt ttgtagtaaa   2040

atcactggtt tatacaaagc tttatttagg gggtaaagtt aagctgctaa aaccccatgt   2100

tggctgctgc tgttgagata ctgtgctttg ggagtaaaaa aagaaagtta tttctttgtc   2160

ttaaagaatt tttaaaaaat tagtcatgag acttattcat ctttccaggg aacatactga   2220

ttggtcttaa aagactagac agttaagtaa aaggtggctg gaacatctat ttttctacaa   2280

aactggaaaa atgaacctgg ttctagaaga atgtacacca aaataaaaca tgtgaagcag   2340

tattgattct ttattgggag tacatttttt taggtctctt aaactttaat ttcacacagt   2400

aaattttgaa tctcataagg aagcatattt gaacctagtc aatttaatct tagtgttccc   2460

ttgaaaactt tttttcccta caaaatttta agtgaaaaat acaatagtaa attaagatta   2520

cactggggaa aaaaatgcag gtatcacttt actccattgt tatctgacct agagcttaat   2580

taagttttag aaatatgtaa taccttccat cattccatca tccttaaatt ctgttaccaa   2640

ataatggcta atgttacaaa aagttatact ccagagaccc aaagcttgac atttacctaa   2700

tgtatgagaa aatattacca attaacaata aagaatgatc atatttttaa cctcttttac   2760

atagcctaat aactcagcaa ggcctcaacg tctgtgctaa tttaaactgc caaatattga   2820

ctgcagcaaa caagaattat attcagaatt tatgagggta ctgttaggag tatactgctt   2880

acaggtttag atatagtctg ttagaattaa aaccaagttt agtgttcata tttacctcat   2940

gggctttatc aagcccatat tacctcagct tatatatagt taccattttt aggtttttaa   3000

ttgtttgaca cttggatgat aaatgcagtc attttattct caagtgctta aaattaatgt   3060

aattaaaagc ttagctgact acagaatagg tgagggtttc ttaaaaatga gatttaaggg   3120

ctgggcacgg tggctcatgc ctgtaatccc agcactttgg gaggccgagg tgggcggatc   3180

acttgaggtt gggagttcat gaccagcttg accaacatga agaaaccctg tctctattaa   3240

aaatacaaaa gtagccaggc atggtggcgc atgcgtgtaa tcccagctac ttgggaggct   3300

gaggcaggag aattgcttga acctgggagg cagaggttgc agtgagtcga gatggtgcca   3360

ttgctctcgt ttgggcaaca agagtgaaac tcttgtctca aaaaaaaaaa aaaatgaggt   3420

ttaagacagt tttgtcatta ctggtgggat ctggtcacac aagatagcat taaacgtgac   3480

atggcacata aaattggtta aaaaattttg ttttttaatt acgtaatgta aaagcccaac   3540

aaacacttta tgcaagattg gaatgtatct tcaaattcag atttaataaa catgtaaaga   3600

tcctctgtat ataaaagttg tatttaatcc c                                  3631


<210>  7302
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  7302

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr Val Leu Leu Ser Met 
    290                 295                 300


Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly Gly 
305                 310                 315                 320


Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu Lys 
                325                 330                 335


Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu Lys 
            340                 345                 350


Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala Ile 
        355                 360                 365


Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu 
    370                 375                 380


Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln 
385                 390                 395                 400


Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn 
                405                 410                 415


Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu 
            420                 425                 430


Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro 
        435                 440                 445


Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu 
    450                 455                 460


Lys Pro Glu Ser Tyr 
465


<210>  7303
<211>  3654
<212>  DNA
<213>  Homo sapiens

<400>  7303
cgaccacccg gcctcggcca ataagcgccg ccctctcgcc cccgtgttac tgggtagaag     60

aaaacaaaaa caaacagagc gagaagggcc agagactctc cgaggcggcg gcagagacag    120

aagagcgggg tcggggccgg ctgaccagga acctgggcga gcagcggcgg gggcccgagg    180

gattctgaag gaagatttcc attaggtaat ttgtttaatc agtgcaagcg aaattaaggg    240

aaaatggatg tagaaaatga gcagatactg aatgtaaacc ctgcagggta ttttccctaa    300

ttctccatgg tgcttcaata gcatgttatt atcataaaaa tgaacagttt tgtggaatag    360

atgaccaaat atcctgataa cttaagtgac tctctctttt ccggtgatga agaaaatgct    420

gggactgagg aaataaagaa tgaaataaat ggaaattgga tttcagcatc ctccattaac    480

gaagctagaa ttaatgccaa ggcaaaaagg cgactaagga aaaactcatc ccgggactct    540

ggcagaggcg attcggtcag cgacagtggg agtgacgccc ttagaagtgg attaactgtg    600

ccaaccagtc caaagggaag gttgctggat aggcgatcca gatctgggaa aggaagggga    660

ctaccaaaga aaggtggtgc aggaggcaaa ggtgtctggg gtacacctgg acaggtgtat    720

gatgtggagg aggtggatgt gaaagatcct aactatgatg atgaccagga gaactgtgtt    780

tatgaaactg tagttttgcc tttggatgaa agggcatttg agaagacttt aacaccaatc    840

atacaggaat attttgagca tggagatact aatgaagttg cggaaatgtt aagagattta    900

aatcttggtg aaatgaaaag tggagtacca gtgttggcag tatccttagc attggagggg    960

aaggctagtc atagagagat gacatctaag cttctttctg acctttgtgg gacagtaatg   1020

agcacaactg atgtggaaaa atcatttgat aaattgttga aagatctacc tgaattagca   1080

ctggatactc ctagagcacc acagttggtg ggccagttta ttgctagagc tgttggagat   1140

ggaattttat gtaataccta tattgatagt tacaaaggaa ctgtagattg tgtgcaggct   1200

agagctgctc tggataaggc taccgtgctt ctgagtatgt ctaaaggtgg aaagcgtaaa   1260

gatagtgtgt ggggctctgg aggtgggcag caatctgtca atcaccttgt taaagagatt   1320

gatatgctgc tgaaagaata tttactctct ggagacatat ctgaagctga acattgcctt   1380

aaggaactgg aagtacctca ttttcaccat gagcttgtat atgaagctat tataatggtt   1440

ttagagtcaa ctggagaaag tacatttaag atgattttgg atttattaaa gtccctttgg   1500

aagtcttcta ccattactgt agaccaaatg aaaagaggtt atgagagaat ttacaatgaa   1560

attccggaca ttaatctgga tgtcccacat tcatactctg tgctggagcg gtttgtagaa   1620

gaatgttttc aggctggaat aatttccaaa caactcagag atctttgtcc ttcaaggggc   1680

agaaagcgtt ttgtaagcga aggagatgga ggtcgtctta aaccagagag ctactgaata   1740

taagaactct tgcagtctta gatgttataa aaatatatat ctgaattgta agagttgtta   1800

gcacaagttt tttttttttt tttttttaag cacttgtttt gggtacaagg catttctgac   1860

attttataaa cctacattta aggggaattt ttaaaggaaa tgttttttct tttttttttg   1920

tttttcgagg gggcaaggag ggacagaaaa gtaacctctt cttaagtgga atattctaat   1980

aagctacctt ttgtaagtgc catgtttatt atctaatcat tccaagtttt gcattgatgt   2040

ctgactgcca ctcctttctt tcaaggacag tgttttttgt agtaaaatca ctggtttata   2100

caaagcttta tttagggggt aaagttaagc tgctaaaacc ccatgttggc tgctgctgtt   2160

gagatactgt gctttgggag taaaaaaaga aagttatttc tttgtcttaa agaattttta   2220

aaaaattagt catgagactt attcatcttt ccagggaaca tactgattgg tcttaaaaga   2280

ctagacagtt aagtaaaagg tggctggaac atctattttt ctacaaaact ggaaaaatga   2340

acctggttct agaagaatgt acaccaaaat aaaacatgtg aagcagtatt gattctttat   2400

tgggagtaca tttttttagg tctcttaaac tttaatttca cacagtaaat tttgaatctc   2460

ataaggaagc atatttgaac ctagtcaatt taatcttagt gttcccttga aaactttttt   2520

tccctacaaa attttaagtg aaaaatacaa tagtaaatta agattacact ggggaaaaaa   2580

atgcaggtat cactttactc cattgttatc tgacctagag cttaattaag ttttagaaat   2640

atgtaatacc ttccatcatt ccatcatcct taaattctgt taccaaataa tggctaatgt   2700

tacaaaaagt tatactccag agacccaaag cttgacattt acctaatgta tgagaaaata   2760

ttaccaatta acaataaaga atgatcatat ttttaacctc ttttacatag cctaataact   2820

cagcaaggcc tcaacgtctg tgctaattta aactgccaaa tattgactgc agcaaacaag   2880

aattatattc agaatttatg agggtactgt taggagtata ctgcttacag gtttagatat   2940

agtctgttag aattaaaacc aagtttagtg ttcatattta cctcatgggc tttatcaagc   3000

ccatattacc tcagcttata tatagttacc atttttaggt ttttaattgt ttgacacttg   3060

gatgataaat gcagtcattt tattctcaag tgcttaaaat taatgtaatt aaaagcttag   3120

ctgactacag aataggtgag ggtttcttaa aaatgagatt taagggctgg gcacggtggc   3180

tcatgcctgt aatcccagca ctttgggagg ccgaggtggg cggatcactt gaggttggga   3240

gttcatgacc agcttgacca acatgaagaa accctgtctc tattaaaaat acaaaagtag   3300

ccaggcatgg tggcgcatgc gtgtaatccc agctacttgg gaggctgagg caggagaatt   3360

gcttgaacct gggaggcaga ggttgcagtg agtcgagatg gtgccattgc tctcgtttgg   3420

gcaacaagag tgaaactctt gtctcaaaaa aaaaaaaaaa tgaggtttaa gacagttttg   3480

tcattactgg tgggatctgg tcacacaaga tagcattaaa cgtgacatgg cacataaaat   3540

tggttaaaaa attttgtttt ttaattacgt aatgtaaaag cccaacaaac actttatgca   3600

agattggaat gtatcttcaa attcagattt aataaacatg taaagatcct ctgt         3654


<210>  7304
<211>  458
<212>  PRT
<213>  Homo sapiens

<400>  7304

Met Thr Lys Tyr Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp 
1               5                   10                  15


Glu Glu Asn Ala Gly Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn 
            20                  25                  30


Trp Ile Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala 
        35                  40                  45


Lys Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp 
    50                  55                  60


Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val 
65                  70                  75                  80


Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly 
                85                  90                  95


Lys Gly Arg Gly Leu Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val 
            100                 105                 110


Trp Gly Thr Pro Gly Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys 
        115                 120                 125


Asp Pro Asn Tyr Asp Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val 
    130                 135                 140


Val Leu Pro Leu Asp Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile 
145                 150                 155                 160


Ile Gln Glu Tyr Phe Glu His Gly Asp Thr Asn Glu Val Ala Glu Met 
                165                 170                 175


Leu Arg Asp Leu Asn Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu 
            180                 185                 190


Ala Val Ser Leu Ala Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr 
        195                 200                 205


Ser Lys Leu Leu Ser Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp 
    210                 215                 220


Val Glu Lys Ser Phe Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala 
225                 230                 235                 240


Leu Asp Thr Pro Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg 
                245                 250                 255


Ala Val Gly Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys 
            260                 265                 270


Gly Thr Val Asp Cys Val Gln Ala Arg Ala Ala Leu Asp Lys Ala Thr 
        275                 280                 285


Val Leu Leu Ser Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp 
    290                 295                 300


Gly Ser Gly Gly Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ile 
305                 310                 315                 320


Asp Met Leu Leu Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala 
                325                 330                 335


Glu His Cys Leu Lys Glu Leu Glu Val Pro His Phe His His Glu Leu 
            340                 345                 350


Val Tyr Glu Ala Ile Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr 
        355                 360                 365


Phe Lys Met Ile Leu Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr 
    370                 375                 380


Ile Thr Val Asp Gln Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu 
385                 390                 395                 400


Ile Pro Asp Ile Asn Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu 
                405                 410                 415


Arg Phe Val Glu Glu Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu 
            420                 425                 430


Arg Asp Leu Cys Pro Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly 
        435                 440                 445


Asp Gly Gly Arg Leu Lys Pro Glu Ser Tyr 
    450                 455


<210>  7305
<211>  714
<212>  DNA
<213>  Homo sapiens

<400>  7305
agaagaaaac aaaaacaaac agagcgagaa gggccagaga ctctccgagg cggcggcaga     60

gacagaagag cggggtcggg gccggctgac caggaacctg ggcgagcagc ggcgggggcc    120

cgagggattc tgaaggaaga tttccattag gtaatttgtt taatcagtgc aagcgaaatt    180

aagggaaaat ggatgtagaa aatgagcaga tactgaatgt aaaccctgca gggtattttc    240

cctaattctc catggtgctt caatagcatg ttattatcat aaaaatgaac agttttgtgg    300

aatagatgac caaatatcct gataacttaa gtgactctct cttttccggt gatgaagaaa    360

atgctgggac tgaggaaata aagaatgaaa taaatggaaa ttggatttca gcatcctcca    420

ttaacgaagc tagaattaat gccaaggcaa aaaggcgact aaggaaaaac tcatcccggg    480

actctggcag aggcgattcg gtcagcgaca gtgggagtga cgcccttaga agtggattaa    540

ctgtgccaac cagtccaaag ggaaggttgc tggataggcg atccagatct gggaaaggaa    600

ggggactacc aaagaaaggt ggtgcaggag gcaaaggtgt ctggggtaca cctggacagg    660

tgtatgatgt ggaggaggtg gatgtgaaag atcctaacta tgatgatgac cagg          714


<210>  7306
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  7306

Met Thr Lys Tyr Pro Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp 
1               5                   10                  15


Glu Glu Asn Ala Gly Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn 
            20                  25                  30


Trp Ile Ser Ala Ser Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala 
        35                  40                  45


Lys Arg Arg Leu Arg Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp 
    50                  55                  60


Ser Val Ser Asp Ser Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val 
65                  70                  75                  80


Pro Thr Ser Pro Lys Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly 
                85                  90                  95


Lys Gly Arg Gly Leu Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val 
            100                 105                 110


Trp Gly Thr Pro Gly Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys 
        115                 120                 125


Asp Pro Asn Tyr Asp Asp Asp 
    130                 135


<210>  7307
<211>  593
<212>  DNA
<213>  Homo sapiens

<400>  7307
agagactctc cgaggcggcg gcagagacag aagagcgggg tcggggccgg ctgaccagga     60

acctgggcga gcagcggcgg gggcccgagg gatcctgata acttaagtga ctctctcttt    120

tccggtgatg aagaaaatgc tgggactgag gaaataaaga atgaaataaa tggaaattgg    180

atttcagcat cctccattaa cgaagctaga attaatgcca aggcaaaaag gcgactaagg    240

aaaaactcat cccgggactc tggcagaggc gattcggtca gcgacagtgg gagtgacgcc    300

cttagaagtg gattaactgt gccaaccagt ccaaagggaa ggttgctgga taggcgatcc    360

agatctggga aaggaagggg actaccaaag aaaggtggtg caggaggcaa aggtgtctgg    420

ggtacacctg gacaggtgta tgatgtggag gaggtggatg tgaaagatcc taactatgat    480

gatgaccagg tatcagtgct ttgctttttc ataatattta aaatgtttat gaactttttt    540

gacttcatgt ttgtagttta ctcatacatg tgtcaaatca tatgtataaa tgt           593


<210>  7308
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  7308

Glu Thr Leu Arg Gly Gly Gly Arg Asp Arg Arg Ala Gly Ser Gly Pro 
1               5                   10                  15


Ala Asp Gln Glu Pro Gly Arg Ala Ala Ala Gly Ala Arg Gly Ile Leu 
            20                  25                  30


Ile Thr 



<210>  7309
<211>  6237
<212>  DNA
<213>  Homo sapiens

<400>  7309
gccccctttc tgtgaaacgc atgccatctt ctccatttgt cagtttgatg ctgtaacgta     60

catggggttt tgcaagagct tcaaaactgt ctgcagacgt caatttcgcc cccctccccc    120

ttgtgagaac tcgctacgta gccagcaact gtgtagtgtc tacaaatgat gaaaacgatc    180

agaaatgcga ttaggtgtcg gggaaaaaag ggtttcccct gtttttaact tgtattttta    240

ctttaattgt tacaatcttg atattcttaa cgtgactttt ttgggaaacc accaagtgct    300

ttttaagcaa ggagttactg gtatttatgc ccttaatatt ccttcattat aggcttattg    360

aatacgttaa tatctcagta agtgtatttg aattataatt gactggcttt ttctgtggta    420

ctaatgtgaa aggaaaaaat attaggactg caaaaataaa tgccgcttga atattatctg    480

tagtgcttgc ttttgcatta ctgtagtaga atgcttttag ctggttttaa gctgctaatt    540

agccgttcgt agccgaagaa tgaatacaag taatcctagt taataaatgg ccaaagcttg    600

actccccaaa atgccagagc aatttatgag gtatatttca ggaaatacat atgtatatat    660

ttcgtggggg agtggagggt ctgtctctta gggaatgtct tggcagttga atacttctga    720

ttgtatattt cgtgtaacac actggagaaa agaacagtgt ttaatgtcag ccttcatttt    780

cttctaactt gtatgtatag ttttctcatc gaaaattcat ttttgtaggt tagtatgaag    840

gaaatagcgt ttggattttt tgctttatat tttcttgttt gggccaatta agggttgtta    900

aataaattgg aaaaaatcct actactttaa agagcgtaaa aacgtggaac atgtcttatc    960

taaactctta aaacgtgttt gttgctgtca aatatgactt gagttcctga tcgggttatc   1020

attgcctaaa gacacaggac tatttttttt attaagataa ctttgttttt atcttaataa   1080

aagagatgat agtcatttcc tgacagtttt gtctgacgga atgccttctg tataatagtt   1140

taaaataatt atttttagtg tttggaaaac agcatttaaa agtttgaaca gcagaagtct   1200

gttttaagaa gcttctgtta acccttgaaa agaatcttcc tgtgggatat taaaattttg   1260

gattgaactt gtgcaaacag tactggattt ggaaggtctg gattctcatc ctggctgttc   1320

cactaagcag ctgtctgtcc ttggacatat cacctaccct ctctgaatct gtttagttgt   1380

gtgtaaggtg gaatacctac ccgaaggttt ttctgtaagg tacattaaat aatacatgta   1440

caattctttt tgaattgtaa agggctttat gaacatcaat tataatcatt tcgcttatta   1500

ggttctgcag aaagtattct ctcaaaagtt atactttcat caagaatgaa aaagactttg   1560

taatggaact ctaaaaaact gaaacacgta tcatatgaca ttattccttt cctatatgta   1620

tttcatgcat ggaattaaaa cagaatgtag ccttttcagc catgaaggat gctgagtgtt   1680

tagatttgca aaccattttt gttcatatat ttatatgaat ctctacatat ttttaagatt   1740

tttttttcat atctaaagtt ggcgggagtt atagtgaaaa gtgattataa agattcacat   1800

atattaattt attcttaaca gaattagaga atgatctcac cattttctta agttcccaag   1860

caatatgata gcatattagt ctgaggatta taccatagta agaagcctat aattttaaca   1920

taaggtccat ttgtttttgt ttcacaaaat aataccgttt tctgaagaaa agggctataa   1980

acttatgtta gcaaatagta gtacataatg aggaatttaa aagtcagttt cacctttgag   2040

tcccaggagg ctctgtatat atcattgtta tcctaaaatg acatctaaca gtaggttaag   2100

ttatatagga aaaaatgtgc ttttctgtaa ttaatttatt aggcattttc actaatttgt   2160

gcattttata tctctgaaga gcacactgct agcaacctga ttgtaaatga ccagaaggac   2220

ttatatccaa cctatgtgac ttaaacatac acttaagtac tctaaaccac tatttaaaaa   2280

atacttctag agagattctg aaatcttaat ttggttgcac tttctggtaa tatatttttt   2340

gaaaactatt ttgatatttc tttcatataa cattattgga tctgtatcac taagttaatt   2400

gtctaaaagg taactgattt catcaaacct tccagtatta ataattttta agccattttg   2460

aaactgaggc ctaaaatact gaaatgctta tgtcgttgta cttactcctt tctgaaatga   2520

tcagattttt aaaaaatgga tttctcatat aaataatatt atcaaaaaag gatttctcat   2580

ataaataata ttatcaaaaa agctgatttt aaaagtttct cccaaagtct tattctagta   2640

attatagaga cctaggtaat gagtggcaga tatatctgcc tttcagatat gccgtaatgt   2700

gaaaaataac acagtcatgt gatattcttt attaactaaa actgtgttgt ttttattttg   2760

gagtagttct cataattcat tggtagggaa ctatccagta tttatattcc tatgtatgta   2820

tatcagatta attttgaggc ttggtattcc taaaagattt ggatgtgtgt atttctttaa   2880

cttgacgtaa acatgtatca caaacatatc ttttaattcc aattaaaggg gtgctttggc   2940

acatgctgaa atctgggatt tttttttttg actttgataa atttatcaaa aagattggaa   3000

ccaaatgtta attagggtaa gttgtctttg aaagtaaagt gaactgtttt atttaatgga   3060

attgtgtgtt ttttgttgtt gtcgtttgtt tttacagtgt gcttaagtaa gtttaattca   3120

gcttaattac atcagtttaa aagatcttga agctttcttt ttttctttta aaaaaacaga   3180

ttctgaagga agatttccat taggtaattt gtttaatcag tgcaagcgaa attaagggaa   3240

aatggatgta gaaaatgagc agatactgaa tgtaaaccct gcagatcctg ataacttaag   3300

tgactctctc ttttccggtg atgaagaaaa tgctgggact gaggaaataa agaatgaaat   3360

aaatggaaat tggatttcag catcctccat taacgaagct agaattaatg ccaaggcaaa   3420

aaggcgacta aggaaaaact catcccggga ctctggcaga ggcgattcgg tcagcgacag   3480

tgggagtgac gcccttagaa gtggattaac tgtgccaacc agtccaaagg gaaggttgct   3540

ggataggcga tccagatctg ggaaaggaag gggactacca aagaaaggtg gtgcaggagg   3600

caaaggtgtc tggggtacac ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga   3660

tcctaactat gatgatgacc aggagaactg tgtttatgaa actgtagttt tgcctttgga   3720

tgaaagggca tttgagaaga ctttaacacc aatcatacag gaatattttg agcatggaga   3780

tactaatgaa gttgcggaaa tgttaagaga tttaaatctt ggtgaaatga aaagtggagt   3840

accagtgttg gcagtatcct tagcattgga ggggaaggct agtcatagag agatgacatc   3900

taagcttctt tctgaccttt gtgggacagt aatgagcaca actgatgtgg aaaaatcatt   3960

tgataaattg ttgaaagatc tacctgaatt agcactggat actcctagag caccacagtt   4020

ggtgggccag tttattgcta gagctgttgg agatggaatt ttatgtaata cctatattga   4080

tagttacaaa ggaactgtag attgtgtgca ggctaggtaa gtaaatcact tttcctactt   4140

agaatttcaa aataggggaa aattctacag gatcctattg aaatgacact tgtgttaatc   4200

agacactctg tacatctgtt tgtcacttct ctatattctc cactgttaaa atggagagac   4260

tattggcatg atataccagg aagaggacag tactataatg gaaaagttct ggagtttagc   4320

taaatcatta attaccttca tgtcaagcca ctcttctttg ggcctcagtt tctttattta   4380

tgaaacaaaa ccattggaca gatctttaag ttctgttttc aggttctagc attgtgtaat   4440

agtttaatat tctaataaga tggataacct taagaagaga ggcctgattt atagttttat   4500

tttgtattta tctactgtag aaatcttagt cagaaagtat ctttttcact cttgtgattt   4560

agtataatta atatgatatt tggtataact aaatgtgata tttgggagtt atgctatttg   4620

atttttctta acttcttgga gacttggact cagccatgtc ttagttttcc tcaggtctat   4680

atattaactt aattttctag ggctacttca catcatagtg gaatggtgtc cctgggtagg   4740

aaggcatgga tctaggtgaa agttaattat atgtgaagtg tttcttctca gtgtagatca   4800

gttattttgt aatgtgtttt gatttttctt gaatgagaaa tgaaatagag catgagaata   4860

ttaacatgag gatcaacttc tttttgctcc tttttgtttt gaaaaagtgt tttgaatttt   4920

attttgcttt tatgttatgt gaaagattta gggcatatag gattttgtca gctttatccc   4980

taatttagta aactttaggt atgtccagct atcaaactta aatttttttc tttctctgta   5040

gagctgctct ggataaggct accgtgcttc tgagtatgtc taaaggtgga aagcgtaaag   5100

atagtgtgtg gggctctgga ggtgggcagc aatctgtcaa tcaccttgtt aaagagattg   5160

atatgctgct gaaagaatat ttactctctg gagacatatc tgaagctgaa cattgcctta   5220

aggaactgga agtacctcat tttcaccatg agcttgtata tgaagctatt ataatggttt   5280

tagagtcaac tggagaaagt acatttaaga tgattttgga tttattaaag tccctttgga   5340

agtcttctac cattactgta gaccaaatga aaagaggtta tgagagaatt tacaatgaaa   5400

ttccggacat taatctggat gtcccacatt catactctgt gctggagcgg tttgtagaag   5460

aatgttttca ggctggaata atttccaaac aactcagaga tctttgtcct tcaaggggca   5520

gaaagcgttt tgtaagcgaa ggagatggag gtcgtcttaa accagagagc tactgaatat   5580

aagaactctt gcagtcttag atgttataaa aatatatatc tgaattgtaa gagttgttag   5640

cacaagtttt tttttttttt ttttttaagc acttgttttg ggtacaaggc atttctgaca   5700

ttttataaac ctacatttaa ggggaatttt taaaggaaat gttttttctt ttttttttgt   5760

ttttcgaggg ggcaaggagg gacagaaaag taacctcttc ttaagtggaa tattctaata   5820

agctaccttt tgtaagtgcc atgtttatta tctaatcatt ccaagttttg cattgatgtc   5880

tgactgccac tcctttcttt caaggacagt gttttttgta gtaaaatcac tggtttatac   5940

aaagctttat ttagggggta aagttaagct gctaaaaccc catgttggct gctgctgttg   6000

agatactgtg ctttgggagt aaaaaaagaa agttatttct ttgtcttaaa gaatttttaa   6060

aaaattagtc atgagactta ttcatctttc cagggaacat actgattggt cttaaaagac   6120

tagacagtta agtaaaaggt ggctggaaca tctatttttc tacaaaactg gaaaaatgaa   6180

cctggttcta gaagaatgta caccaaaata aaacatgtga agcagtattg attcttt      6237


<210>  7310
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  7310

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg 
    290


<210>  7311
<211>  6633
<212>  DNA
<213>  Homo sapiens

<400>  7311
gccccctttc tgtgaaacgc atgccatctt ctccatttgt cagtttgatg ctgtaacgta     60

catggggttt tgcaagagct tcaaaactgt ctgcagacgt caatttcgcc cccctccccc    120

ttgtgagaac tcgctacgta gccagcaact gtgtagtgtc tacaaatgat gaaaacgatc    180

agaaatgcga ttaggtgtcg gggaaaaaag ggtttcccct gtttttaact tgtattttta    240

ctttaattgt tacaatcttg atattcttaa cgtgactttt ttgggaaacc accaagtgct    300

ttttaagcaa ggagttactg gtatttatgc ccttaatatt ccttcattat aggcttattg    360

aatacgttaa tatctcagta agtgtatttg aattataatt gactggcttt ttctgtggta    420

ctaatgtgaa aggaaaaaat attaggactg caaaaataaa tgccgcttga atattatctg    480

tagtgcttgc ttttgcatta ctgtagtaga atgcttttag ctggttttaa gctgctaatt    540

agccgttcgt agccgaagaa tgaatacaag taatcctagt taataaatgg ccaaagcttg    600

actccccaaa atgccagagc aatttatgag gtatatttca ggaaatacat atgtatatat    660

ttcgtggggg agtggagggt ctgtctctta gggaatgtct tggcagttga atacttctga    720

ttgtatattt cgtgtaacac actggagaaa agaacagtgt ttaatgtcag ccttcatttt    780

cttctaactt gtatgtatag ttttctcatc gaaaattcat ttttgtaggt tagtatgaag    840

gaaatagcgt ttggattttt tgctttatat tttcttgttt gggccaatta agggttgtta    900

aataaattgg aaaaaatcct actactttaa agagcgtaaa aacgtggaac atgtcttatc    960

taaactctta aaacgtgttt gttgctgtca aatatgactt gagttcctga tcgggttatc   1020

attgcctaaa gacacaggac tatttttttt attaagataa ctttgttttt atcttaataa   1080

aagagatgat agtcatttcc tgacagtttt gtctgacgga atgccttctg tataatagtt   1140

taaaataatt atttttagtg tttggaaaac agcatttaaa agtttgaaca gcagaagtct   1200

gttttaagaa gcttctgtta acccttgaaa agaatcttcc tgtgggatat taaaattttg   1260

gattgaactt gtgcaaacag tactggattt ggaaggtctg gattctcatc ctggctgttc   1320

cactaagcag ctgtctgtcc ttggacatat cacctaccct ctctgaatct gtttagttgt   1380

gtgtaaggtg gaatacctac ccgaaggttt ttctgtaagg tacattaaat aatacatgta   1440

caattctttt tgaattgtaa agggctttat gaacatcaat tataatcatt tcgcttatta   1500

ggttctgcag aaagtattct ctcaaaagtt atactttcat caagaatgaa aaagactttg   1560

taatggaact ctaaaaaact gaaacacgta tcatatgaca ttattccttt cctatatgta   1620

tttcatgcat ggaattaaaa cagaatgtag ccttttcagc catgaaggat gctgagtgtt   1680

tagatttgca aaccattttt gttcatatat ttatatgaat ctctacatat ttttaagatt   1740

tttttttcat atctaaagtt ggcgggagtt atagtgaaaa gtgattataa agattcacat   1800

atattaattt attcttaaca gaattagaga atgatctcac cattttctta agttcccaag   1860

caatatgata gcatattagt ctgaggatta taccatagta agaagcctat aattttaaca   1920

taaggtccat ttgtttttgt ttcacaaaat aataccgttt tctgaagaaa agggctataa   1980

acttatgtta gcaaatagta gtacataatg aggaatttaa aagtcagttt cacctttgag   2040

tcccaggagg ctctgtatat atcattgtta tcctaaaatg acatctaaca gtaggttaag   2100

ttatatagga aaaaatgtgc ttttctgtaa ttaatttatt aggcattttc actaatttgt   2160

gcattttata tctctgaaga gcacactgct agcaacctga ttgtaaatga ccagaaggac   2220

ttatatccaa cctatgtgac ttaaacatac acttaagtac tctaaaccac tatttaaaaa   2280

atacttctag agagattctg aaatcttaat ttggttgcac tttctggtaa tatatttttt   2340

gaaaactatt ttgatatttc tttcatataa cattattgga tctgtatcac taagttaatt   2400

gtctaaaagg taactgattt catcaaacct tccagtatta ataattttta agccattttg   2460

aaactgaggc ctaaaatact gaaatgctta tgtcgttgta cttactcctt tctgaaatga   2520

tcagattttt aaaaaatgga tttctcatat aaataatatt atcaaaaaag gatttctcat   2580

ataaataata ttatcaaaaa agctgatttt aaaagtttct cccaaagtct tattctagta   2640

attatagaga cctaggtaat gagtggcaga tatatctgcc tttcagatat gccgtaatgt   2700

gaaaaataac acagtcatgt gatattcttt attaactaaa actgtgttgt ttttattttg   2760

gagtagttct cataattcat tggtagggaa ctatccagta tttatattcc tatgtatgta   2820

tatcagatta attttgaggc ttggtattcc taaaagattt ggatgtgtgt atttctttaa   2880

cttgacgtaa acatgtatca caaacatatc ttttaattcc aattaaaggg gtgctttggc   2940

acatgctgaa atctgggatt tttttttttg actttgataa atttatcaaa aagattggaa   3000

ccaaatgtta attagggtaa gttgtctttg aaagtaaagt gaactgtttt atttaatgga   3060

attgtgtgtt ttttgttgtt gtcgtttgtt tttacagtgt gcttaagtaa gtttaattca   3120

gcttaattac atcagtttaa aagatcttga agctttcttt ttttctttta aaaaaacaga   3180

ttctgaagga agatttccat taggtaattt gtttaatcag tgcaagcgaa attaagggaa   3240

aatggatgta gaaaatgagc agatactgaa tgtaaaccct gcagatcctg ataacttaag   3300

tgactctctc ttttccggtg atgaagaaaa tgctgggact gaggaaataa agaatgaaat   3360

aaatggaaat tggatttcag catcctccat taacgaagct agaattaatg ccaaggcaaa   3420

aaggcgacta aggaaaaact catcccggga ctctggcaga ggcgattcgg tcagcgacag   3480

tgggagtgac gcccttagaa gtggattaac tgtgccaacc agtccaaagg gaaggttgct   3540

ggataggcga tccagatctg ggaaaggaag gggactacca aagaaaggtg gtgcaggagg   3600

caaaggtgtc tggggtacac ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga   3660

tcctaactat gatgatgacc aggagaactg tgtttatgaa actgtagttt tgcctttgga   3720

tgaaagggca tttgagaaga ctttaacacc aatcatacag gaatattttg agcatggaga   3780

tactaatgaa gttgcggaaa tgttaagaga tttaaatctt ggtgaaatga aaagtggagt   3840

accagtgttg gcagtatcct tagcattgga ggggaaggct agtcatagag agatgacatc   3900

taagcttctt tctgaccttt gtgggacagt aatgagcaca actgatgtgg aaaaatcatt   3960

tgataaattg ttgaaagatc tacctgaatt agcactggat actcctagag caccacagtt   4020

ggtgggccag tttattgcta gagctgttgg agatggaatt ttatgtaata cctatattga   4080

tagttacaaa ggaactgtag attgtgtgca ggctaggtaa gtaaatcact tttcctactt   4140

agaatttcaa aataggggaa aattctacag gatcctattg aaatgacact tgtgttaatc   4200

agacactctg tacatctgtt tgtcacttct ctatattctc cactgttaaa atggagagac   4260

tattggcatg atataccagg aagaggacag tactataatg gaaaagttct ggagtttagc   4320

taaatcatta attaccttca tgtcaagcca ctcttctttg ggcctcagtt tctttattta   4380

tgaaacaaaa ccattggaca gatctttaag ttctgttttc aggttctagc attgtgtaat   4440

agtttaatat tctaataaga tggataacct taagaagaga ggcctgattt atagttttat   4500

tttgtattta tctactgtag aaatcttagt cagaaagtat ctttttcact cttgtgattt   4560

agtataatta atatgatatt tggtataact aaatgtgata tttgggagtt atgctatttg   4620

atttttctta acttcttgga gacttggact cagccatgtc ttagttttcc tcaggtctat   4680

atattaactt aattttctag ggctacttca catcatagtg gaatggtgtc cctgggtagg   4740

aaggcatgga tctaggtgaa agttaattat atgtgaagtg tttcttctca gtgtagatca   4800

gttattttgt aatgtgtttt gatttttctt gaatgagaaa tgaaatagag catgagaata   4860

ttaacatgag gatcaacttc tttttgctcc tttttgtttt gaaaaagtgt tttgaatttt   4920

attttgcttt tatgttatgt gaaagattta gggcatatag gattttgtca gctttatccc   4980

taatttagta aactttaggt atgtccagct atcaaactta aatttttttc tttctctgta   5040

gagctgctct ggataaggct accgtgcttc tgagtatgtc taaaggtgga aagcgtaaag   5100

atagtgtgtg gggctctgga ggtgggcagc aatctgtcaa tcaccttgtt aaagagattg   5160

atatgctgct gaaagaatat ttactctctg gagacatatc tgaagctgaa cattgcctta   5220

aggaactgga agtacctcat tttcaccatg agcttgtata tgaagctatt ataatggttt   5280

tagagtcaac tggagaaagt acatttaaga tgattttgga tttattaaag tccctttgga   5340

agtcttctac cattactgta gaccaaatga aaagaggtta tgagagaatt tacaatgaaa   5400

ttccggacat taatctggat gtcccacatt catactctgt gctggagcgg tttgtagaag   5460

aatgttttca ggctggaata atttccaaac aactcagaga tctttgtcct tcaaggggca   5520

gaaagcgttt tgtaagcgaa ggagatggag gtcgtcttaa accagagagc tactgaatat   5580

aagaactctt gcagtcttag atgttataaa aatatatatc tgaattgtaa gagttgttag   5640

cacaagtttt tttttttttt ttttttaagc acttgttttg ggtacaaggc atttctgaca   5700

ttttataaac ctacatttaa ggggaatttt taaaggaaat gttttttctt ttttttttgt   5760

ttttcgaggg ggcaaggagg gacagaaaag taacctcttc ttaagtggaa tattctaata   5820

agctaccttt tgtaagtgcc atgtttatta tctaatcatt ccaagttttg cattgatgtc   5880

tgactgccac tcctttcttt caaggacagt gttttttgta gtaaaatcac tggtttatac   5940

aaagctttat ttagggggta aagttaagct gctaaaaccc catgttggct gctgctgttg   6000

agatactgtg ctttgggagt aaaaaaagaa agttatttct ttgtcttaaa gaatttttaa   6060

aaaattagtc atgagactta ttcatctttc cagggaacat actgattggt cttaaaagac   6120

tagacagtta agtaaaaggt ggctggaaca tctatttttc tacaaaactg gaaaaatgaa   6180

cctggttcta gaagaatgta caccaaaata aaacatgtga agcagtattg attctttatt   6240

gggagtacat ttttttaggt ctcttaaact ttaatttcac acagtaaatt ttgaatctca   6300

taaggaagca tatttgaacc tagtcaattt aatcttagtg ttcccttgaa aacttttttt   6360

ccctacaaaa ttttaagtga aaaatacaat agtaaattaa gattacactg gggaaaaaaa   6420

tgcaggtatc actttactcc attgttatct gacctagagc ttaattaagt tttagaaata   6480

tgtaatacct tccatcattc catcatcctt aaattctgtt accaaataat ggctaatgtt   6540

acaaaaagtt atactccaga gacccaaagc ttgacattta cctaatgtat gagaaaatat   6600

taccaattaa caataaagaa tgatcatatt ttt                                6633


<210>  7312
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  7312

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg 
    290


<210>  7313
<211>  7493
<212>  DNA
<213>  Homo sapiens

<400>  7313
gccccctttc tgtgaaacgc atgccatctt ctccatttgt cagtttgatg ctgtaacgta     60

catggggttt tgcaagagct tcaaaactgt ctgcagacgt caatttcgcc cccctccccc    120

ttgtgagaac tcgctacgta gccagcaact gtgtagtgtc tacaaatgat gaaaacgatc    180

agaaatgcga ttaggtgtcg gggaaaaaag ggtttcccct gtttttaact tgtattttta    240

ctttaattgt tacaatcttg atattcttaa cgtgactttt ttgggaaacc accaagtgct    300

ttttaagcaa ggagttactg gtatttatgc ccttaatatt ccttcattat aggcttattg    360

aatacgttaa tatctcagta agtgtatttg aattataatt gactggcttt ttctgtggta    420

ctaatgtgaa aggaaaaaat attaggactg caaaaataaa tgccgcttga atattatctg    480

tagtgcttgc ttttgcatta ctgtagtaga atgcttttag ctggttttaa gctgctaatt    540

agccgttcgt agccgaagaa tgaatacaag taatcctagt taataaatgg ccaaagcttg    600

actccccaaa atgccagagc aatttatgag gtatatttca ggaaatacat atgtatatat    660

ttcgtggggg agtggagggt ctgtctctta gggaatgtct tggcagttga atacttctga    720

ttgtatattt cgtgtaacac actggagaaa agaacagtgt ttaatgtcag ccttcatttt    780

cttctaactt gtatgtatag ttttctcatc gaaaattcat ttttgtaggt tagtatgaag    840

gaaatagcgt ttggattttt tgctttatat tttcttgttt gggccaatta agggttgtta    900

aataaattgg aaaaaatcct actactttaa agagcgtaaa aacgtggaac atgtcttatc    960

taaactctta aaacgtgttt gttgctgtca aatatgactt gagttcctga tcgggttatc   1020

attgcctaaa gacacaggac tatttttttt attaagataa ctttgttttt atcttaataa   1080

aagagatgat agtcatttcc tgacagtttt gtctgacgga atgccttctg tataatagtt   1140

taaaataatt atttttagtg tttggaaaac agcatttaaa agtttgaaca gcagaagtct   1200

gttttaagaa gcttctgtta acccttgaaa agaatcttcc tgtgggatat taaaattttg   1260

gattgaactt gtgcaaacag tactggattt ggaaggtctg gattctcatc ctggctgttc   1320

cactaagcag ctgtctgtcc ttggacatat cacctaccct ctctgaatct gtttagttgt   1380

gtgtaaggtg gaatacctac ccgaaggttt ttctgtaagg tacattaaat aatacatgta   1440

caattctttt tgaattgtaa agggctttat gaacatcaat tataatcatt tcgcttatta   1500

ggttctgcag aaagtattct ctcaaaagtt atactttcat caagaatgaa aaagactttg   1560

taatggaact ctaaaaaact gaaacacgta tcatatgaca ttattccttt cctatatgta   1620

tttcatgcat ggaattaaaa cagaatgtag ccttttcagc catgaaggat gctgagtgtt   1680

tagatttgca aaccattttt gttcatatat ttatatgaat ctctacatat ttttaagatt   1740

tttttttcat atctaaagtt ggcgggagtt atagtgaaaa gtgattataa agattcacat   1800

atattaattt attcttaaca gaattagaga atgatctcac cattttctta agttcccaag   1860

caatatgata gcatattagt ctgaggatta taccatagta agaagcctat aattttaaca   1920

taaggtccat ttgtttttgt ttcacaaaat aataccgttt tctgaagaaa agggctataa   1980

acttatgtta gcaaatagta gtacataatg aggaatttaa aagtcagttt cacctttgag   2040

tcccaggagg ctctgtatat atcattgtta tcctaaaatg acatctaaca gtaggttaag   2100

ttatatagga aaaaatgtgc ttttctgtaa ttaatttatt aggcattttc actaatttgt   2160

gcattttata tctctgaaga gcacactgct agcaacctga ttgtaaatga ccagaaggac   2220

ttatatccaa cctatgtgac ttaaacatac acttaagtac tctaaaccac tatttaaaaa   2280

atacttctag agagattctg aaatcttaat ttggttgcac tttctggtaa tatatttttt   2340

gaaaactatt ttgatatttc tttcatataa cattattgga tctgtatcac taagttaatt   2400

gtctaaaagg taactgattt catcaaacct tccagtatta ataattttta agccattttg   2460

aaactgaggc ctaaaatact gaaatgctta tgtcgttgta cttactcctt tctgaaatga   2520

tcagattttt aaaaaatgga tttctcatat aaataatatt atcaaaaaag gatttctcat   2580

ataaataata ttatcaaaaa agctgatttt aaaagtttct cccaaagtct tattctagta   2640

attatagaga cctaggtaat gagtggcaga tatatctgcc tttcagatat gccgtaatgt   2700

gaaaaataac acagtcatgt gatattcttt attaactaaa actgtgttgt ttttattttg   2760

gagtagttct cataattcat tggtagggaa ctatccagta tttatattcc tatgtatgta   2820

tatcagatta attttgaggc ttggtattcc taaaagattt ggatgtgtgt atttctttaa   2880

cttgacgtaa acatgtatca caaacatatc ttttaattcc aattaaaggg gtgctttggc   2940

acatgctgaa atctgggatt tttttttttg actttgataa atttatcaaa aagattggaa   3000

ccaaatgtta attagggtaa gttgtctttg aaagtaaagt gaactgtttt atttaatgga   3060

attgtgtgtt ttttgttgtt gtcgtttgtt tttacagtgt gcttaagtaa gtttaattca   3120

gcttaattac atcagtttaa aagatcttga agctttcttt ttttctttta aaaaaacaga   3180

ttctgaagga agatttccat taggtaattt gtttaatcag tgcaagcgaa attaagggaa   3240

aatggatgta gaaaatgagc agatactgaa tgtaaaccct gcagatcctg ataacttaag   3300

tgactctctc ttttccggtg atgaagaaaa tgctgggact gaggaaataa agaatgaaat   3360

aaatggaaat tggatttcag catcctccat taacgaagct agaattaatg ccaaggcaaa   3420

aaggcgacta aggaaaaact catcccggga ctctggcaga ggcgattcgg tcagcgacag   3480

tgggagtgac gcccttagaa gtggattaac tgtgccaacc agtccaaagg gaaggttgct   3540

ggataggcga tccagatctg ggaaaggaag gggactacca aagaaaggtg gtgcaggagg   3600

caaaggtgtc tggggtacac ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga   3660

tcctaactat gatgatgacc aggagaactg tgtttatgaa actgtagttt tgcctttgga   3720

tgaaagggca tttgagaaga ctttaacacc aatcatacag gaatattttg agcatggaga   3780

tactaatgaa gttgcggaaa tgttaagaga tttaaatctt ggtgaaatga aaagtggagt   3840

accagtgttg gcagtatcct tagcattgga ggggaaggct agtcatagag agatgacatc   3900

taagcttctt tctgaccttt gtgggacagt aatgagcaca actgatgtgg aaaaatcatt   3960

tgataaattg ttgaaagatc tacctgaatt agcactggat actcctagag caccacagtt   4020

ggtgggccag tttattgcta gagctgttgg agatggaatt ttatgtaata cctatattga   4080

tagttacaaa ggaactgtag attgtgtgca ggctaggtaa gtaaatcact tttcctactt   4140

agaatttcaa aataggggaa aattctacag gatcctattg aaatgacact tgtgttaatc   4200

agacactctg tacatctgtt tgtcacttct ctatattctc cactgttaaa atggagagac   4260

tattggcatg atataccagg aagaggacag tactataatg gaaaagttct ggagtttagc   4320

taaatcatta attaccttca tgtcaagcca ctcttctttg ggcctcagtt tctttattta   4380

tgaaacaaaa ccattggaca gatctttaag ttctgttttc aggttctagc attgtgtaat   4440

agtttaatat tctaataaga tggataacct taagaagaga ggcctgattt atagttttat   4500

tttgtattta tctactgtag aaatcttagt cagaaagtat ctttttcact cttgtgattt   4560

agtataatta atatgatatt tggtataact aaatgtgata tttgggagtt atgctatttg   4620

atttttctta acttcttgga gacttggact cagccatgtc ttagttttcc tcaggtctat   4680

atattaactt aattttctag ggctacttca catcatagtg gaatggtgtc cctgggtagg   4740

aaggcatgga tctaggtgaa agttaattat atgtgaagtg tttcttctca gtgtagatca   4800

gttattttgt aatgtgtttt gatttttctt gaatgagaaa tgaaatagag catgagaata   4860

ttaacatgag gatcaacttc tttttgctcc tttttgtttt gaaaaagtgt tttgaatttt   4920

attttgcttt tatgttatgt gaaagattta gggcatatag gattttgtca gctttatccc   4980

taatttagta aactttaggt atgtccagct atcaaactta aatttttttc tttctctgta   5040

gagctgctct ggataaggct accgtgcttc tgagtatgtc taaaggtgga aagcgtaaag   5100

atagtgtgtg gggctctgga ggtgggcagc aatctgtcaa tcaccttgtt aaagagattg   5160

atatgctgct gaaagaatat ttactctctg gagacatatc tgaagctgaa cattgcctta   5220

aggaactgga agtacctcat tttcaccatg agcttgtata tgaagctatt ataatggttt   5280

tagagtcaac tggagaaagt acatttaaga tgattttgga tttattaaag tccctttgga   5340

agtcttctac cattactgta gaccaaatga aaagaggtta tgagagaatt tacaatgaaa   5400

ttccggacat taatctggat gtcccacatt catactctgt gctggagcgg tttgtagaag   5460

aatgttttca ggctggaata atttccaaac aactcagaga tctttgtcct tcaaggggca   5520

gaaagcgttt tgtaagcgaa ggagatggag gtcgtcttaa accagagagc tactgaatat   5580

aagaactctt gcagtcttag atgttataaa aatatatatc tgaattgtaa gagttgttag   5640

cacaagtttt tttttttttt ttttttaagc acttgttttg ggtacaaggc atttctgaca   5700

ttttataaac ctacatttaa ggggaatttt taaaggaaat gttttttctt ttttttttgt   5760

ttttcgaggg ggcaaggagg gacagaaaag taacctcttc ttaagtggaa tattctaata   5820

agctaccttt tgtaagtgcc atgtttatta tctaatcatt ccaagttttg cattgatgtc   5880

tgactgccac tcctttcttt caaggacagt gttttttgta gtaaaatcac tggtttatac   5940

aaagctttat ttagggggta aagttaagct gctaaaaccc catgttggct gctgctgttg   6000

agatactgtg ctttgggagt aaaaaaagaa agttatttct ttgtcttaaa gaatttttaa   6060

aaaattagtc atgagactta ttcatctttc cagggaacat actgattggt cttaaaagac   6120

tagacagtta agtaaaaggt ggctggaaca tctatttttc tacaaaactg gaaaaatgaa   6180

cctggttcta gaagaatgta caccaaaata aaacatgtga agcagtattg attctttatt   6240

gggagtacat ttttttaggt ctcttaaact ttaatttcac acagtaaatt ttgaatctca   6300

taaggaagca tatttgaacc tagtcaattt aatcttagtg ttcccttgaa aacttttttt   6360

ccctacaaaa ttttaagtga aaaatacaat agtaaattaa gattacactg gggaaaaaaa   6420

tgcaggtatc actttactcc attgttatct gacctagagc ttaattaagt tttagaaata   6480

tgtaatacct tccatcattc catcatcctt aaattctgtt accaaataat ggctaatgtt   6540

acaaaaagtt atactccaga gacccaaagc ttgacattta cctaatgtat gagaaaatat   6600

taccaattaa caataaagaa tgatcatatt tttaacctct tttacatagc ctaataactc   6660

agcaaggcct caacgtctgt gctaatttaa actgccaaat attgactgca gcaaacaaga   6720

attatattca gaatttatga gggtactgtt aggagtatac tgcttacagg tttagatata   6780

gtctgttaga attaaaacca agtttagtgt tcatatttac ctcatgggct ttatcaagcc   6840

catattacct cagcttatat atagttacca tttttaggtt tttaattgtt tgacacttgg   6900

atgataaatg cagtcatttt attctcaagt gcttaaaatt aatgtaatta aaagcttagc   6960

tgactacaga ataggtgagg gtttcttaaa aatgagattt aagggctggg cacggtggct   7020

catgcctgta atcccagcac tttgggaggc cgaggtgggc ggatcacttg aggttgggag   7080

ttcatgacca gcttgaccaa catgaagaaa ccctgtctct attaaaaata caaaagtagc   7140

caggcatggt ggcgcatgcg tgtaatccca gctacttggg aggctgaggc aggagaattg   7200

cttgaacctg ggaggcagag gttgcagtga gtcgagatgg tgccattgct ctcgtttggg   7260

caacaagagt gaaactcttg tctcaaaaaa aaaaaaaaat gaggtttaag acagttttgt   7320

cattactggt gggatctggt cacacaagat agcattaaac gtgacatggc acataaaatt   7380

ggttaaaaaa ttttgttttt taattacgta atgtaaaagc ccaacaaaca ctttatgcaa   7440

gattggaatg tatcttcaaa ttcagattta ataaacatgt aaagatcctc tgt          7493


<210>  7314
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  7314

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg 
    290


<210>  7315
<211>  7516
<212>  DNA
<213>  Homo sapiens

<400>  7315
gccccctttc tgtgaaacgc atgccatctt ctccatttgt cagtttgatg ctgtaacgta     60

catggggttt tgcaagagct tcaaaactgt ctgcagacgt caatttcgcc cccctccccc    120

ttgtgagaac tcgctacgta gccagcaact gtgtagtgtc tacaaatgat gaaaacgatc    180

agaaatgcga ttaggtgtcg gggaaaaaag ggtttcccct gtttttaact tgtattttta    240

ctttaattgt tacaatcttg atattcttaa cgtgactttt ttgggaaacc accaagtgct    300

ttttaagcaa ggagttactg gtatttatgc ccttaatatt ccttcattat aggcttattg    360

aatacgttaa tatctcagta agtgtatttg aattataatt gactggcttt ttctgtggta    420

ctaatgtgaa aggaaaaaat attaggactg caaaaataaa tgccgcttga atattatctg    480

tagtgcttgc ttttgcatta ctgtagtaga atgcttttag ctggttttaa gctgctaatt    540

agccgttcgt agccgaagaa tgaatacaag taatcctagt taataaatgg ccaaagcttg    600

actccccaaa atgccagagc aatttatgag gtatatttca ggaaatacat atgtatatat    660

ttcgtggggg agtggagggt ctgtctctta gggaatgtct tggcagttga atacttctga    720

ttgtatattt cgtgtaacac actggagaaa agaacagtgt ttaatgtcag ccttcatttt    780

cttctaactt gtatgtatag ttttctcatc gaaaattcat ttttgtaggt tagtatgaag    840

gaaatagcgt ttggattttt tgctttatat tttcttgttt gggccaatta agggttgtta    900

aataaattgg aaaaaatcct actactttaa agagcgtaaa aacgtggaac atgtcttatc    960

taaactctta aaacgtgttt gttgctgtca aatatgactt gagttcctga tcgggttatc   1020

attgcctaaa gacacaggac tatttttttt attaagataa ctttgttttt atcttaataa   1080

aagagatgat agtcatttcc tgacagtttt gtctgacgga atgccttctg tataatagtt   1140

taaaataatt atttttagtg tttggaaaac agcatttaaa agtttgaaca gcagaagtct   1200

gttttaagaa gcttctgtta acccttgaaa agaatcttcc tgtgggatat taaaattttg   1260

gattgaactt gtgcaaacag tactggattt ggaaggtctg gattctcatc ctggctgttc   1320

cactaagcag ctgtctgtcc ttggacatat cacctaccct ctctgaatct gtttagttgt   1380

gtgtaaggtg gaatacctac ccgaaggttt ttctgtaagg tacattaaat aatacatgta   1440

caattctttt tgaattgtaa agggctttat gaacatcaat tataatcatt tcgcttatta   1500

ggttctgcag aaagtattct ctcaaaagtt atactttcat caagaatgaa aaagactttg   1560

taatggaact ctaaaaaact gaaacacgta tcatatgaca ttattccttt cctatatgta   1620

tttcatgcat ggaattaaaa cagaatgtag ccttttcagc catgaaggat gctgagtgtt   1680

tagatttgca aaccattttt gttcatatat ttatatgaat ctctacatat ttttaagatt   1740

tttttttcat atctaaagtt ggcgggagtt atagtgaaaa gtgattataa agattcacat   1800

atattaattt attcttaaca gaattagaga atgatctcac cattttctta agttcccaag   1860

caatatgata gcatattagt ctgaggatta taccatagta agaagcctat aattttaaca   1920

taaggtccat ttgtttttgt ttcacaaaat aataccgttt tctgaagaaa agggctataa   1980

acttatgtta gcaaatagta gtacataatg aggaatttaa aagtcagttt cacctttgag   2040

tcccaggagg ctctgtatat atcattgtta tcctaaaatg acatctaaca gtaggttaag   2100

ttatatagga aaaaatgtgc ttttctgtaa ttaatttatt aggcattttc actaatttgt   2160

gcattttata tctctgaaga gcacactgct agcaacctga ttgtaaatga ccagaaggac   2220

ttatatccaa cctatgtgac ttaaacatac acttaagtac tctaaaccac tatttaaaaa   2280

atacttctag agagattctg aaatcttaat ttggttgcac tttctggtaa tatatttttt   2340

gaaaactatt ttgatatttc tttcatataa cattattgga tctgtatcac taagttaatt   2400

gtctaaaagg taactgattt catcaaacct tccagtatta ataattttta agccattttg   2460

aaactgaggc ctaaaatact gaaatgctta tgtcgttgta cttactcctt tctgaaatga   2520

tcagattttt aaaaaatgga tttctcatat aaataatatt atcaaaaaag gatttctcat   2580

ataaataata ttatcaaaaa agctgatttt aaaagtttct cccaaagtct tattctagta   2640

attatagaga cctaggtaat gagtggcaga tatatctgcc tttcagatat gccgtaatgt   2700

gaaaaataac acagtcatgt gatattcttt attaactaaa actgtgttgt ttttattttg   2760

gagtagttct cataattcat tggtagggaa ctatccagta tttatattcc tatgtatgta   2820

tatcagatta attttgaggc ttggtattcc taaaagattt ggatgtgtgt atttctttaa   2880

cttgacgtaa acatgtatca caaacatatc ttttaattcc aattaaaggg gtgctttggc   2940

acatgctgaa atctgggatt tttttttttg actttgataa atttatcaaa aagattggaa   3000

ccaaatgtta attagggtaa gttgtctttg aaagtaaagt gaactgtttt atttaatgga   3060

attgtgtgtt ttttgttgtt gtcgtttgtt tttacagtgt gcttaagtaa gtttaattca   3120

gcttaattac atcagtttaa aagatcttga agctttcttt ttttctttta aaaaaacaga   3180

ttctgaagga agatttccat taggtaattt gtttaatcag tgcaagcgaa attaagggaa   3240

aatggatgta gaaaatgagc agatactgaa tgtaaaccct gcagatcctg ataacttaag   3300

tgactctctc ttttccggtg atgaagaaaa tgctgggact gaggaaataa agaatgaaat   3360

aaatggaaat tggatttcag catcctccat taacgaagct agaattaatg ccaaggcaaa   3420

aaggcgacta aggaaaaact catcccggga ctctggcaga ggcgattcgg tcagcgacag   3480

tgggagtgac gcccttagaa gtggattaac tgtgccaacc agtccaaagg gaaggttgct   3540

ggataggcga tccagatctg ggaaaggaag gggactacca aagaaaggtg gtgcaggagg   3600

caaaggtgtc tggggtacac ctggacaggt gtatgatgtg gaggaggtgg atgtgaaaga   3660

tcctaactat gatgatgacc aggagaactg tgtttatgaa actgtagttt tgcctttgga   3720

tgaaagggca tttgagaaga ctttaacacc aatcatacag gaatattttg agcatggaga   3780

tactaatgaa gttgcggaaa tgttaagaga tttaaatctt ggtgaaatga aaagtggagt   3840

accagtgttg gcagtatcct tagcattgga ggggaaggct agtcatagag agatgacatc   3900

taagcttctt tctgaccttt gtgggacagt aatgagcaca actgatgtgg aaaaatcatt   3960

tgataaattg ttgaaagatc tacctgaatt agcactggat actcctagag caccacagtt   4020

ggtgggccag tttattgcta gagctgttgg agatggaatt ttatgtaata cctatattga   4080

tagttacaaa ggaactgtag attgtgtgca ggctaggtaa gtaaatcact tttcctactt   4140

agaatttcaa aataggggaa aattctacag gatcctattg aaatgacact tgtgttaatc   4200

agacactctg tacatctgtt tgtcacttct ctatattctc cactgttaaa atggagagac   4260

tattggcatg atataccagg aagaggacag tactataatg gaaaagttct ggagtttagc   4320

taaatcatta attaccttca tgtcaagcca ctcttctttg ggcctcagtt tctttattta   4380

tgaaacaaaa ccattggaca gatctttaag ttctgttttc aggttctagc attgtgtaat   4440

agtttaatat tctaataaga tggataacct taagaagaga ggcctgattt atagttttat   4500

tttgtattta tctactgtag aaatcttagt cagaaagtat ctttttcact cttgtgattt   4560

agtataatta atatgatatt tggtataact aaatgtgata tttgggagtt atgctatttg   4620

atttttctta acttcttgga gacttggact cagccatgtc ttagttttcc tcaggtctat   4680

atattaactt aattttctag ggctacttca catcatagtg gaatggtgtc cctgggtagg   4740

aaggcatgga tctaggtgaa agttaattat atgtgaagtg tttcttctca gtgtagatca   4800

gttattttgt aatgtgtttt gatttttctt gaatgagaaa tgaaatagag catgagaata   4860

ttaacatgag gatcaacttc tttttgctcc tttttgtttt gaaaaagtgt tttgaatttt   4920

attttgcttt tatgttatgt gaaagattta gggcatatag gattttgtca gctttatccc   4980

taatttagta aactttaggt atgtccagct atcaaactta aatttttttc tttctctgta   5040

gagctgctct ggataaggct accgtgcttc tgagtatgtc taaaggtgga aagcgtaaag   5100

atagtgtgtg gggctctgga ggtgggcagc aatctgtcaa tcaccttgtt aaagagattg   5160

atatgctgct gaaagaatat ttactctctg gagacatatc tgaagctgaa cattgcctta   5220

aggaactgga agtacctcat tttcaccatg agcttgtata tgaagctatt ataatggttt   5280

tagagtcaac tggagaaagt acatttaaga tgattttgga tttattaaag tccctttgga   5340

agtcttctac cattactgta gaccaaatga aaagaggtta tgagagaatt tacaatgaaa   5400

ttccggacat taatctggat gtcccacatt catactctgt gctggagcgg tttgtagaag   5460

aatgttttca ggctggaata atttccaaac aactcagaga tctttgtcct tcaaggggca   5520

gaaagcgttt tgtaagcgaa ggagatggag gtcgtcttaa accagagagc tactgaatat   5580

aagaactctt gcagtcttag atgttataaa aatatatatc tgaattgtaa gagttgttag   5640

cacaagtttt tttttttttt ttttttaagc acttgttttg ggtacaaggc atttctgaca   5700

ttttataaac ctacatttaa ggggaatttt taaaggaaat gttttttctt ttttttttgt   5760

ttttcgaggg ggcaaggagg gacagaaaag taacctcttc ttaagtggaa tattctaata   5820

agctaccttt tgtaagtgcc atgtttatta tctaatcatt ccaagttttg cattgatgtc   5880

tgactgccac tcctttcttt caaggacagt gttttttgta gtaaaatcac tggtttatac   5940

aaagctttat ttagggggta aagttaagct gctaaaaccc catgttggct gctgctgttg   6000

agatactgtg ctttgggagt aaaaaaagaa agttatttct ttgtcttaaa gaatttttaa   6060

aaaattagtc atgagactta ttcatctttc cagggaacat actgattggt cttaaaagac   6120

tagacagtta agtaaaaggt ggctggaaca tctatttttc tacaaaactg gaaaaatgaa   6180

cctggttcta gaagaatgta caccaaaata aaacatgtga agcagtattg attctttatt   6240

gggagtacat ttttttaggt ctcttaaact ttaatttcac acagtaaatt ttgaatctca   6300

taaggaagca tatttgaacc tagtcaattt aatcttagtg ttcccttgaa aacttttttt   6360

ccctacaaaa ttttaagtga aaaatacaat agtaaattaa gattacactg gggaaaaaaa   6420

tgcaggtatc actttactcc attgttatct gacctagagc ttaattaagt tttagaaata   6480

tgtaatacct tccatcattc catcatcctt aaattctgtt accaaataat ggctaatgtt   6540

acaaaaagtt atactccaga gacccaaagc ttgacattta cctaatgtat gagaaaatat   6600

taccaattaa caataaagaa tgatcatatt tttaacctct tttacatagc ctaataactc   6660

agcaaggcct caacgtctgt gctaatttaa actgccaaat attgactgca gcaaacaaga   6720

attatattca gaatttatga gggtactgtt aggagtatac tgcttacagg tttagatata   6780

gtctgttaga attaaaacca agtttagtgt tcatatttac ctcatgggct ttatcaagcc   6840

catattacct cagcttatat atagttacca tttttaggtt tttaattgtt tgacacttgg   6900

atgataaatg cagtcatttt attctcaagt gcttaaaatt aatgtaatta aaagcttagc   6960

tgactacaga ataggtgagg gtttcttaaa aatgagattt aagggctggg cacggtggct   7020

catgcctgta atcccagcac tttgggaggc cgaggtgggc ggatcacttg aggttgggag   7080

ttcatgacca gcttgaccaa catgaagaaa ccctgtctct attaaaaata caaaagtagc   7140

caggcatggt ggcgcatgcg tgtaatccca gctacttggg aggctgaggc aggagaattg   7200

cttgaacctg ggaggcagag gttgcagtga gtcgagatgg tgccattgct ctcgtttggg   7260

caacaagagt gaaactcttg tctcaaaaaa aaaaaaaaat gaggtttaag acagttttgt   7320

cattactggt gggatctggt cacacaagat agcattaaac gtgacatggc acataaaatt   7380

ggttaaaaaa ttttgttttt taattacgta atgtaaaagc ccaacaaaca ctttatgcaa   7440

gattggaatg tatcttcaaa ttcagattta ataaacatgt aaagatcctc tgtatataaa   7500

agttgtattt aatccc                                                   7516


<210>  7316
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  7316

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Gly Ala Gly Gly Lys Gly Val Trp Gly Thr Pro Gly 
        115                 120                 125


Gln Val Tyr Asp Val Glu Glu Val Asp Val Lys Asp Pro Asn Tyr Asp 
    130                 135                 140


Asp Asp Gln Glu Asn Cys Val Tyr Glu Thr Val Val Leu Pro Leu Asp 
145                 150                 155                 160


Glu Arg Ala Phe Glu Lys Thr Leu Thr Pro Ile Ile Gln Glu Tyr Phe 
                165                 170                 175


Glu His Gly Asp Thr Asn Glu Val Ala Glu Met Leu Arg Asp Leu Asn 
            180                 185                 190


Leu Gly Glu Met Lys Ser Gly Val Pro Val Leu Ala Val Ser Leu Ala 
        195                 200                 205


Leu Glu Gly Lys Ala Ser His Arg Glu Met Thr Ser Lys Leu Leu Ser 
    210                 215                 220


Asp Leu Cys Gly Thr Val Met Ser Thr Thr Asp Val Glu Lys Ser Phe 
225                 230                 235                 240


Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu Ala Leu Asp Thr Pro Arg 
                245                 250                 255


Ala Pro Gln Leu Val Gly Gln Phe Ile Ala Arg Ala Val Gly Asp Gly 
            260                 265                 270


Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr Lys Gly Thr Val Asp Cys 
        275                 280                 285


Val Gln Ala Arg 
    290


<210>  7317
<211>  461
<212>  DNA
<213>  Homo sapiens

<400>  7317
agtgcaagcg aaattaaggg aaaatggatg tagaaaatga gcagatactg aatgtaaacc     60

ctgcagatcc tgataactta agtgactctc tcttttccgg tgatgaagaa aatgctggga    120

ctgaggaaat aaagaatgaa ataaatggaa attggatttc agcatcctcc attaacgaag    180

ctagaattaa tgccaaggca aaaaggcgac taaggaaaaa ctcatcccgg gactctggca    240

gaggcgattc ggtcagcgac agtgggagtg acgcccttag aagtggatta actgtgccaa    300

ccagtccaaa gggaaggttg ctggataggc gatccagatc tgggaaagga aggggactac    360

caaagaaagg ttggtatata tcatgtccaa caaatggaag ataaacaagt ggaaaaaaat    420

tgtctggttc ttgtactaca ctttccttgt tctaggaatg a                        461


<210>  7318
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  7318

Met Asp Val Glu Asn Glu Gln Ile Leu Asn Val Asn Pro Ala Asp Pro 
1               5                   10                  15


Asp Asn Leu Ser Asp Ser Leu Phe Ser Gly Asp Glu Glu Asn Ala Gly 
            20                  25                  30


Thr Glu Glu Ile Lys Asn Glu Ile Asn Gly Asn Trp Ile Ser Ala Ser 
        35                  40                  45


Ser Ile Asn Glu Ala Arg Ile Asn Ala Lys Ala Lys Arg Arg Leu Arg 
    50                  55                  60


Lys Asn Ser Ser Arg Asp Ser Gly Arg Gly Asp Ser Val Ser Asp Ser 
65                  70                  75                  80


Gly Ser Asp Ala Leu Arg Ser Gly Leu Thr Val Pro Thr Ser Pro Lys 
                85                  90                  95


Gly Arg Leu Leu Asp Arg Arg Ser Arg Ser Gly Lys Gly Arg Gly Leu 
            100                 105                 110


Pro Lys Lys Gly Trp Tyr Ile Ser Cys Pro Thr Asn Gly Arg 
        115                 120                 125


<210>  7319
<211>  4899
<212>  DNA
<213>  Homo sapiens

<400>  7319
gtttatgaac ttttttgact tcatgtttgt agtttactca tacatgtgtc aaatcatatg     60

tataaatgtt ttggattagg aaaccaagta aactgacagt aatacatgca taactttcac    120

ttggtttctg tagtgagtca aaaatagctc tttagaaatt cacttaggat tattaagttg    180

tccatttttc agtaaattct gttaatatag tttgtttcta tagtaatgat aattgagaat    240

atcttctttt gaatattatg agttacagat attagattcc ttttaaatat tactgtttag    300

aatggtaact atataataca ttttgttttg gggacatgcg catctttctt ttagggataa    360

tgctgaaaat gtaaattttt aatagattgt gaagtgaatt ttttattttt tttaatggaa    420

aaaatttaaa gtagaatagt ataatctgct tgtactcctc tcttagcttt acaaacttaa    480

ataattacaa actcataggc agtcttgttt aattccattt actctccgtc ttctattggc    540

ccctttgccc caccctgttt tggattattt tgaagcaaat cccaaatgtt ttgattatgt    600

tttttgaaaa tttgtctttg cacaaggtga gacacggtga tggaaatttt agacaggaaa    660

acgttaagag tatgtgttag gttgttttta ttgtgtgttg tatgtatgta tttaagtgtt    720

ttaactaata gatatggaaa tatttctaag agaacatgaa aaatatgaaa ctagtaggat    780

tcaagtactg tagaatcttt gctaaaaatg tattaatctt tcaagtatat gtttttaggc    840

tgaagccagt cacaagttgt aaatatagca gtcccctctt atccgtggtt tcactttccg    900

cagtttcagt tacccatggt ccaatgtggt ttgaaaatat tgagtggaaa ctttcagaag    960

taattcataa gttttaaatt gcatgccatt ctgagtagtg tgatgagatc tcctgctgtc   1020

cagcttcatc cacctcatcc tgcccaggat gtgagccatt ccgttgtcca gcgtgtatcc   1080

gcaatgtata cactactcgt gcattcgtca catggtagct gtctaggtta tcggattgag   1140

aaaacagtat ttattgggtt cggtactatc tgtggtttaa ggcatcctcg gacggggctt   1200

ggaacatacc ccttgtagat aagggggcac tacatttcag agctttttta gcatggggag   1260

agaggaatgg tttgatgatg gatgttaatt ttctttttga aatttcaatt gaacagtgct   1320

tttttcctta gagatttttt ttctgtcact acaacattga tctttgtgtt atacttttta   1380

ttataataat gctaatcgtg aaggctttgg ttcctgcttc attttttttt aaagtgaaat   1440

tttaattaaa acaccattta tgataggaag ccatcatgaa actttttgat tactaaaaga   1500

ttggttttga gagagacata aaaattttga gagaaaaaat taacagaaga catgggggtt   1560

gggagcaaat tatgtatttg ctgtggttaa tgattctaat ctatatattg gcttattgta   1620

ttctgatttt gtaaaagagc agtgacatat aaattctact atttttatta tgatttatta   1680

ttattatttt ttagctttgt tgtccaggct ggagtgcagt gatgaattat agctcactgc   1740

agcctcgaac tcttgggctt aagagatcct tctgcctcag cttcctgagt agctaggact   1800

acaggggcaa gctaccatgt ctggctaatt tttaaaactt ttttgtagag acagggtctt   1860

gctatgtttc ccaggctagt attgaactcc aggcctcaag tgaacctccc gcctttgcct   1920

cccaaagtgt tgggattata ggtatgagtc tccttgcctg gcctagattc tatttttata   1980

tgcgatcaat gtatgtagca tgtctttgtc ttgtgctaag tggggattat taaccactta   2040

gaatataaaa ttgtacaaca atttcacttg tttatttgca ttttgttttt tataactctt   2100

actccctttt cccctcaaag gagaactgtg tttatgaaac tgtagttttg cctttggatg   2160

aaagggcatt tgagaagact ttaacaccaa tcatacagga atattttgag catggagata   2220

ctaatgaagt tgcggaaatg ttaagagatt taaatcttgg tgaaatgaaa agtggagtac   2280

cagtgttggc agtatcctta gcattggagg ggaaggctag tcatagagag atgacatcta   2340

agcttctttc tgacctttgt gggacagtaa tgagcacaac tgatgtggaa aaatcatttg   2400

ataaattgtt gaaagatcta cctgaattag cactggatac tcctagagca ccacagttgg   2460

tgggccagtt tattgctaga gctgttggag atggaatttt atgtaatacc tatattgata   2520

gttacaaagg aactgtagat tgtgtgcagg ctaggtaagt aaatcacttt tcctacttag   2580

aatttcaaaa taggggaaaa ttctacagga tcctattgaa atgacacttg tgttaatcag   2640

acactctgta catctgtttg tcacttctct atattctcca ctgttaaaat ggagagacta   2700

ttggcatgat ataccaggaa gaggacagta ctataatgga aaagttctgg agtttagcta   2760

aatcattaat taccttcatg tcaagccact cttctttggg cctcagtttc tttatttatg   2820

aaacaaaacc attggacaga tctttaagtt ctgttttcag gttctagcat tgtgtaatag   2880

tttaatattc taataagatg gataacctta agaagagagg cctgatttat agttttattt   2940

tgtatttatc tactgtagaa atcttagtca gaaagtatct ttttcactct tgtgatttag   3000

tataattaat atgatatttg gtataactaa atgtgatatt tgggagttat gctatttgat   3060

ttttcttaac ttcttggaga cttggactca gccatgtctt agttttcctc aggtctatat   3120

attaacttaa ttttctaggg ctacttcaca tcatagtgga atggtgtccc tgggtaggaa   3180

ggcatggatc taggtgaaag ttaattatat gtgaagtgtt tcttctcagt gtagatcagt   3240

tattttgtaa tgtgttttga tttttcttga atgagaaatg aaatagagca tgagaatatt   3300

aacatgagga tcaacttctt tttgctcctt tttgttttga aaaagtgttt tgaattttat   3360

tttgctttta tgttatgtga aagatttagg gcatatagga ttttgtcagc tttatcccta   3420

atttagtaaa ctttaggtat gtccagctat caaacttaaa tttttttctt tctctgtaga   3480

gctgctctgg ataaggctac cgtgcttctg agtatgtcta aaggtggaaa gcgtaaagat   3540

agtgtgtggg gctctggagg tgggcagcaa tctgtcaatc accttgttaa agaggtaatg   3600

attgggtatt gtttttaact taatttatat gtattcctct gagtgaaata aattgtggct   3660

actagctggt atttttatgg acaaaaatta agttcggtct tacagctgca attggaaaat   3720

gaaataattt ttttaatatg tggctttata accttttatt ataaattata tgattaaaaa   3780

atgagtctgt taaaatggct ttcatgaata attataagca agccatctat gaacttcaaa   3840

ggaatgcctg aaatcttttt cttatagtat tatttaataa ttttcaaatg ctgttgaaat   3900

gagattttct gtgttttagc tattcaataa atacgctttt atatgagcaa tttaaaacta   3960

gatagtctta aataatgagt tatgaattat gagcactaga gcagatcaga gtgttagatt   4020

tttgtgagga cattcactac ccatatgcat gttttaaaag aaaattgatt gtaatcccag   4080

cactttgaga ggctgaggcg ggtggattgc ttgaggccag gagtttgaga ccagcctggt   4140

caacatggtg aaaccccgtt tctactaaaa atacataata attagccagg catggtggtg   4200

cgcacctgta atcccagcta ctcgggaggc tgaggcacca gtattgcttg aacccaggag   4260

gaggaggttg cagtgagctg agatcacacc actgcactcc agcatgggtg acagagcaag   4320

actctgtctc aaaaaaaaaa aaaaaaaaaa gcgatttatt gcattaaaat gccagattta   4380

ttccctatgg attttttttt tttctggctg caatgtggtg tcctataaca agaaaccaaa   4440

aaacagaaaa aactccttat ctgcagatct ctttaagaaa aggcatgcaa ctagaagatt   4500

tgtagttcat gtgcttctga tttttgagta taatcttttc atgtaactac aattttgatt   4560

tttagtaagt cttttaatga ggtgtgtgtg tgtgtttgtg tatgtgtatc tagcttaagt   4620

gttaaggagt tcaaattgta gttagagcct tgactgtttt tgcttttata tatgttaaaa   4680

tagatgagtc agtgtttgta atgtcgtgat tgcagtatct gttttttaaa aattaaacaa   4740

ttattagaaa aattgaggta taaaaatagt caagatgcca gggcaattag gcaggaaaga   4800

taaaaggcat ccagattgga aaggaggaga taaaactagt tgtattccca gataacatga   4860

tctgtataca gaaaatttga atgaatccac attttttaa                          4899


<210>  7320
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  7320

Met Leu Arg Asp Leu Asn Leu Gly Glu Met Lys Ser Gly Val Pro Val 
1               5                   10                  15


Leu Ala Val Ser Leu Ala Leu Glu Gly Lys Ala Ser His Arg Glu Met 
            20                  25                  30


Thr Ser Lys Leu Leu Ser Asp Leu Cys Gly Thr Val Met Ser Thr Thr 
        35                  40                  45


Asp Val Glu Lys Ser Phe Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu 
    50                  55                  60


Ala Leu Asp Thr Pro Arg Ala Pro Gln Leu Val Gly Gln Phe Ile Ala 
65                  70                  75                  80


Arg Ala Val Gly Asp Gly Ile Leu Cys Asn Thr Tyr Ile Asp Ser Tyr 
                85                  90                  95


Lys Gly Thr Val Asp Cys Val Gln Ala Arg 
            100                 105


<210>  7321
<211>  906
<212>  DNA
<213>  Homo sapiens

<400>  7321
catgggggtt gggagcaaat tatgtatttg ctgtggttaa tgattctaat ctatatattg     60

gcttattgta ttctgatttt gtaaaagagc agtgacatat aaattctact atttttatta    120

tgatttatta ttattatttt ttagctttgt tgtccaggct ggagtgcagt gatgaattat    180

agctcactgc agcctcgaac tcttgggctt aagagatcct tctgcctcag cttcctgagt    240

agctaggact acaggggcaa gctaccatgt ctggctaatt tttaaaactt ttttgtagag    300

acagggtctt gctatgtttc ccaggctagt attgaactcc aggcctcaag tgaacctccc    360

gcctttgcct cccaaagtgt tgggattata ggtatgagtc tccttgcctg gcctagattc    420

tatttttata tgcgatcaat gtatgtagca tgtctttgtc ttgtgctaag tggggattat    480

taaccactta gaatataaaa ttgtacaaca atttcacttg tttatttgca ttttgttttt    540

tataactctt actccctttt cccctcaaag gagaactgtg tttatgaaac tgtagttttg    600

cctttggatg aaagggcatt tgagaagact ttaacaccaa tcatacagga atattttgag    660

catggagata ctaatgaagt tgcggaaatg ttaagagatt taaatcttgg tgaaatgaaa    720

agtggagtac cagtgttggc agtatcctta gcattggagg ggaaggctag tcatagagag    780

atgacatcta agcttctttc tgacctttgt gggacagtaa tgagcacaac tgatgtggaa    840

aaatcatttg ataaattgtt gaaagatcta cctgaattag cactggatac tcctagagca    900

ccacag                                                               906


<210>  7322
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  7322

Met Leu Arg Asp Leu Asn Leu Gly Glu Met Lys Ser Gly Val Pro Val 
1               5                   10                  15


Leu Ala Val Ser Leu Ala Leu Glu Gly Lys Ala Ser His Arg Glu Met 
            20                  25                  30


Thr Ser Lys Leu Leu Ser Asp Leu Cys Gly Thr Val Met Ser Thr Thr 
        35                  40                  45


Asp Val Glu Lys Ser Phe Asp Lys Leu Leu Lys Asp Leu Pro Glu Leu 
    50                  55                  60


Ala Leu Asp Thr Pro Arg Ala Pro 
65                  70


<210>  7323
<211>  590
<212>  DNA
<213>  Homo sapiens

<400>  7323
tagagctgct ctggataagg ctaccgtgct tctgagtatg tctaaaggtg gaaagcgtaa     60

agatagtgtg tggggctctg gaggtgggca gcaatctgtc aatcaccttg ttaaagagat    120

tgatatgctg ctgaaagaat atttactctc tggagacata tctgaagctg aacattgcct    180

taaggaactg gaagtacctc attttcacca tgagcttgta tatgaagcta ttataatggt    240

tttagagtca actggagaaa gtacatttaa gatgattttg gatttattaa agtccctttg    300

gaagtcttct accattactg tagaccaaat gaaaagaggt tatgagagaa tttacaatga    360

aattccggac attaatctgg atgtcccaca ttcatactct gtgctggagc ggtttgtaga    420

agaatgtttt caggctggaa taatttccaa acaactcaga gatctttgtc cttcaagggg    480

cagaaagcgt tttgtaagcg aaggagatgg aggtcgtctt aaaccagaga gctactgaat    540

ataagaactc ttgcagtctt agatgttata aaaatatata tctgaattgt               590


<210>  7324
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  7324

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu 
            20                  25                  30


Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu 
        35                  40                  45


Lys Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala 
    50                  55                  60


Ile Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile 
65                  70                  75                  80


Leu Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp 
                85                  90                  95


Gln Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile 
            100                 105                 110


Asn Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu 
        115                 120                 125


Glu Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys 
    130                 135                 140


Pro Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg 
145                 150                 155                 160


Leu Lys Pro Glu Ser Tyr 
                165


<210>  7325
<211>  996
<212>  DNA
<213>  Homo sapiens

<400>  7325
tagagctgct ctggataagg ctaccgtgct tctgagtatg tctaaaggtg gaaagcgtaa     60

agatagtgtg tggggctctg gaggtgggca gcaatctgtc aatcaccttg ttaaagagat    120

tgatatgctg ctgaaagaat atttactctc tggagacata tctgaagctg aacattgcct    180

taaggaactg gaagtacctc attttcacca tgagcttgta tatgaagcta ttataatggt    240

tttagagtca actggagaaa gtacatttaa gatgattttg gatttattaa agtccctttg    300

gaagtcttct accattactg tagaccaaat gaaaagaggt tatgagagaa tttacaatga    360

aattccggac attaatctgg atgtcccaca ttcatactct gtgctggagc ggtttgtaga    420

agaatgtttt caggctggaa taatttccaa acaactcaga gatctttgtc cttcaagggg    480

cagaaagcgt tttgtaagcg aaggagatgg aggtcgtctt aaaccagaga gctactgaat    540

ataagaactc ttgcagtctt agatgttata aaaatatata tctgaattgt aagagttgtt    600

agcacaagtt tttttttttt ttttttttaa gcacttgttt tgggtacaag gcatttctga    660

cattttataa acctacattt aaggggaatt tttaaaggaa atgttttttc tttttttttt    720

gtttttcgag ggggcaagga gggacagaaa agtaacctct tcttaagtgg aatattctaa    780

taagctacct tttgtaagtg ccatgtttat tatctaatca ttccaagttt tgcattgatg    840

tctgactgcc actcctttct ttcaaggaca gtgttttttg tagtaaaatc actggtttat    900

acaaagcttt atttaggggg taaagttaag ctgctaaaac cccatgttgg ctgctgctgt    960

tgagatactg tgctttggga gtaaaaaaag aaagtt                              996


<210>  7326
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  7326

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ile Asp Met Leu Leu 
            20                  25                  30


Lys Glu Tyr Leu Leu Ser Gly Asp Ile Ser Glu Ala Glu His Cys Leu 
        35                  40                  45


Lys Glu Leu Glu Val Pro His Phe His His Glu Leu Val Tyr Glu Ala 
    50                  55                  60


Ile Ile Met Val Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile 
65                  70                  75                  80


Leu Asp Leu Leu Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp 
                85                  90                  95


Gln Met Lys Arg Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile 
            100                 105                 110


Asn Leu Asp Val Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu 
        115                 120                 125


Glu Cys Phe Gln Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys 
    130                 135                 140


Pro Ser Arg Gly Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg 
145                 150                 155                 160


Leu Lys Pro Glu Ser Tyr 
                165


<210>  7327
<211>  1084
<212>  DNA
<213>  Homo sapiens

<400>  7327
gctctggata aggctaccgt gcttctgagt atgtctaaag gtggaaagcg taaagatagt     60

gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc ttgttaaaga ggctattata    120

atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt attaaagtcc    180

ctttggaagt cttctaccat tactgtagac caaatgaaaa gaggttatga gagaatttac    240

aatgaaattc cggacattaa tctggatgtc ccacattcat actctgtgct ggagcggttt    300

gtagaagaat gttttcaggc tggaataatt tccaaacaac tcagagatct ttgtccttca    360

aggggcagaa agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac    420

tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga attgtaagag    480

ttgttagcac aagttttttt tttttttttt tttaagcact tgttttgggt acaaggcatt    540

tctgacattt tataaaccta catttaaggg gaatttttaa aggaaatgtt ttttcttttt    600

tttttgtttt tcgagggggc aaggagggac agaaaagtaa cctcttctta agtggaatat    660

tctaataagc taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat    720

tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta aaatcactgg    780

tttatacaaa gctttattta gggggtaaag ttaagctgct aaaaccccat gttggctgct    840

gctgttgaga tactgtgctt tgggagtaaa aaaagaaagt tatttctttg tcttaaagaa    900

tttttaaaaa attagtcatg agacttattc atctttccag ggaacatact gattggtctt    960

aaaagactag acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa   1020

aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc agtattgatt   1080

cttt                                                                1084


<210>  7328
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  7328

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ala Ile Ile Met Val 
            20                  25                  30


Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu 
        35                  40                  45


Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg 
    50                  55                  60


Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val 
65                  70                  75                  80


Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln 
                85                  90                  95


Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg Gly 
            100                 105                 110


Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys Pro Glu 
        115                 120                 125


Ser Tyr 
    130


<210>  7329
<211>  1480
<212>  DNA
<213>  Homo sapiens

<400>  7329
gctctggata aggctaccgt gcttctgagt atgtctaaag gtggaaagcg taaagatagt     60

gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc ttgttaaaga ggctattata    120

atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt attaaagtcc    180

ctttggaagt cttctaccat tactgtagac caaatgaaaa gaggttatga gagaatttac    240

aatgaaattc cggacattaa tctggatgtc ccacattcat actctgtgct ggagcggttt    300

gtagaagaat gttttcaggc tggaataatt tccaaacaac tcagagatct ttgtccttca    360

aggggcagaa agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac    420

tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga attgtaagag    480

ttgttagcac aagttttttt tttttttttt tttaagcact tgttttgggt acaaggcatt    540

tctgacattt tataaaccta catttaaggg gaatttttaa aggaaatgtt ttttcttttt    600

tttttgtttt tcgagggggc aaggagggac agaaaagtaa cctcttctta agtggaatat    660

tctaataagc taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat    720

tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta aaatcactgg    780

tttatacaaa gctttattta gggggtaaag ttaagctgct aaaaccccat gttggctgct    840

gctgttgaga tactgtgctt tgggagtaaa aaaagaaagt tatttctttg tcttaaagaa    900

tttttaaaaa attagtcatg agacttattc atctttccag ggaacatact gattggtctt    960

aaaagactag acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa   1020

aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc agtattgatt   1080

ctttattggg agtacatttt tttaggtctc ttaaacttta atttcacaca gtaaattttg   1140

aatctcataa ggaagcatat ttgaacctag tcaatttaat cttagtgttc ccttgaaaac   1200

tttttttccc tacaaaattt taagtgaaaa atacaatagt aaattaagat tacactgggg   1260

aaaaaaatgc aggtatcact ttactccatt gttatctgac ctagagctta attaagtttt   1320

agaaatatgt aataccttcc atcattccat catccttaaa ttctgttacc aaataatggc   1380

taatgttaca aaaagttata ctccagagac ccaaagcttg acatttacct aatgtatgag   1440

aaaatattac caattaacaa taaagaatga tcatattttt                         1480


<210>  7330
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  7330

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ala Ile Ile Met Val 
            20                  25                  30


Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu 
        35                  40                  45


Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg 
    50                  55                  60


Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val 
65                  70                  75                  80


Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln 
                85                  90                  95


Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg Gly 
            100                 105                 110


Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys Pro Glu 
        115                 120                 125


Ser Tyr 
    130


<210>  7331
<211>  2340
<212>  DNA
<213>  Homo sapiens

<400>  7331
gctctggata aggctaccgt gcttctgagt atgtctaaag gtggaaagcg taaagatagt     60

gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc ttgttaaaga ggctattata    120

atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt attaaagtcc    180

ctttggaagt cttctaccat tactgtagac caaatgaaaa gaggttatga gagaatttac    240

aatgaaattc cggacattaa tctggatgtc ccacattcat actctgtgct ggagcggttt    300

gtagaagaat gttttcaggc tggaataatt tccaaacaac tcagagatct ttgtccttca    360

aggggcagaa agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac    420

tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga attgtaagag    480

ttgttagcac aagttttttt tttttttttt tttaagcact tgttttgggt acaaggcatt    540

tctgacattt tataaaccta catttaaggg gaatttttaa aggaaatgtt ttttcttttt    600

tttttgtttt tcgagggggc aaggagggac agaaaagtaa cctcttctta agtggaatat    660

tctaataagc taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat    720

tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta aaatcactgg    780

tttatacaaa gctttattta gggggtaaag ttaagctgct aaaaccccat gttggctgct    840

gctgttgaga tactgtgctt tgggagtaaa aaaagaaagt tatttctttg tcttaaagaa    900

tttttaaaaa attagtcatg agacttattc atctttccag ggaacatact gattggtctt    960

aaaagactag acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa   1020

aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc agtattgatt   1080

ctttattggg agtacatttt tttaggtctc ttaaacttta atttcacaca gtaaattttg   1140

aatctcataa ggaagcatat ttgaacctag tcaatttaat cttagtgttc ccttgaaaac   1200

tttttttccc tacaaaattt taagtgaaaa atacaatagt aaattaagat tacactgggg   1260

aaaaaaatgc aggtatcact ttactccatt gttatctgac ctagagctta attaagtttt   1320

agaaatatgt aataccttcc atcattccat catccttaaa ttctgttacc aaataatggc   1380

taatgttaca aaaagttata ctccagagac ccaaagcttg acatttacct aatgtatgag   1440

aaaatattac caattaacaa taaagaatga tcatattttt aacctctttt acatagccta   1500

ataactcagc aaggcctcaa cgtctgtgct aatttaaact gccaaatatt gactgcagca   1560

aacaagaatt atattcagaa tttatgaggg tactgttagg agtatactgc ttacaggttt   1620

agatatagtc tgttagaatt aaaaccaagt ttagtgttca tatttacctc atgggcttta   1680

tcaagcccat attacctcag cttatatata gttaccattt ttaggttttt aattgtttga   1740

cacttggatg ataaatgcag tcattttatt ctcaagtgct taaaattaat gtaattaaaa   1800

gcttagctga ctacagaata ggtgagggtt tcttaaaaat gagatttaag ggctgggcac   1860

ggtggctcat gcctgtaatc ccagcacttt gggaggccga ggtgggcgga tcacttgagg   1920

ttgggagttc atgaccagct tgaccaacat gaagaaaccc tgtctctatt aaaaatacaa   1980

aagtagccag gcatggtggc gcatgcgtgt aatcccagct acttgggagg ctgaggcagg   2040

agaattgctt gaacctggga ggcagaggtt gcagtgagtc gagatggtgc cattgctctc   2100

gtttgggcaa caagagtgaa actcttgtct caaaaaaaaa aaaaaatgag gtttaagaca   2160

gttttgtcat tactggtggg atctggtcac acaagatagc attaaacgtg acatggcaca   2220

taaaattggt taaaaaattt tgttttttaa ttacgtaatg taaaagccca acaaacactt   2280

tatgcaagat tggaatgtat cttcaaattc agatttaata aacatgtaaa gatcctctgt   2340


<210>  7332
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  7332

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ala Ile Ile Met Val 
            20                  25                  30


Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu 
        35                  40                  45


Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg 
    50                  55                  60


Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val 
65                  70                  75                  80


Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln 
                85                  90                  95


Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg Gly 
            100                 105                 110


Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys Pro Glu 
        115                 120                 125


Ser Tyr 
    130


<210>  7333
<211>  2363
<212>  DNA
<213>  Homo sapiens

<400>  7333
gctctggata aggctaccgt gcttctgagt atgtctaaag gtggaaagcg taaagatagt     60

gtgtggggct ctggaggtgg gcagcaatct gtcaatcacc ttgttaaaga ggctattata    120

atggttttag agtcaactgg agaaagtaca tttaagatga ttttggattt attaaagtcc    180

ctttggaagt cttctaccat tactgtagac caaatgaaaa gaggttatga gagaatttac    240

aatgaaattc cggacattaa tctggatgtc ccacattcat actctgtgct ggagcggttt    300

gtagaagaat gttttcaggc tggaataatt tccaaacaac tcagagatct ttgtccttca    360

aggggcagaa agcgttttgt aagcgaagga gatggaggtc gtcttaaacc agagagctac    420

tgaatataag aactcttgca gtcttagatg ttataaaaat atatatctga attgtaagag    480

ttgttagcac aagttttttt tttttttttt tttaagcact tgttttgggt acaaggcatt    540

tctgacattt tataaaccta catttaaggg gaatttttaa aggaaatgtt ttttcttttt    600

tttttgtttt tcgagggggc aaggagggac agaaaagtaa cctcttctta agtggaatat    660

tctaataagc taccttttgt aagtgccatg tttattatct aatcattcca agttttgcat    720

tgatgtctga ctgccactcc tttctttcaa ggacagtgtt ttttgtagta aaatcactgg    780

tttatacaaa gctttattta gggggtaaag ttaagctgct aaaaccccat gttggctgct    840

gctgttgaga tactgtgctt tgggagtaaa aaaagaaagt tatttctttg tcttaaagaa    900

tttttaaaaa attagtcatg agacttattc atctttccag ggaacatact gattggtctt    960

aaaagactag acagttaagt aaaaggtggc tggaacatct atttttctac aaaactggaa   1020

aaatgaacct ggttctagaa gaatgtacac caaaataaaa catgtgaagc agtattgatt   1080

ctttattggg agtacatttt tttaggtctc ttaaacttta atttcacaca gtaaattttg   1140

aatctcataa ggaagcatat ttgaacctag tcaatttaat cttagtgttc ccttgaaaac   1200

tttttttccc tacaaaattt taagtgaaaa atacaatagt aaattaagat tacactgggg   1260

aaaaaaatgc aggtatcact ttactccatt gttatctgac ctagagctta attaagtttt   1320

agaaatatgt aataccttcc atcattccat catccttaaa ttctgttacc aaataatggc   1380

taatgttaca aaaagttata ctccagagac ccaaagcttg acatttacct aatgtatgag   1440

aaaatattac caattaacaa taaagaatga tcatattttt aacctctttt acatagccta   1500

ataactcagc aaggcctcaa cgtctgtgct aatttaaact gccaaatatt gactgcagca   1560

aacaagaatt atattcagaa tttatgaggg tactgttagg agtatactgc ttacaggttt   1620

agatatagtc tgttagaatt aaaaccaagt ttagtgttca tatttacctc atgggcttta   1680

tcaagcccat attacctcag cttatatata gttaccattt ttaggttttt aattgtttga   1740

cacttggatg ataaatgcag tcattttatt ctcaagtgct taaaattaat gtaattaaaa   1800

gcttagctga ctacagaata ggtgagggtt tcttaaaaat gagatttaag ggctgggcac   1860

ggtggctcat gcctgtaatc ccagcacttt gggaggccga ggtgggcgga tcacttgagg   1920

ttgggagttc atgaccagct tgaccaacat gaagaaaccc tgtctctatt aaaaatacaa   1980

aagtagccag gcatggtggc gcatgcgtgt aatcccagct acttgggagg ctgaggcagg   2040

agaattgctt gaacctggga ggcagaggtt gcagtgagtc gagatggtgc cattgctctc   2100

gtttgggcaa caagagtgaa actcttgtct caaaaaaaaa aaaaaatgag gtttaagaca   2160

gttttgtcat tactggtggg atctggtcac acaagatagc attaaacgtg acatggcaca   2220

taaaattggt taaaaaattt tgttttttaa ttacgtaatg taaaagccca acaaacactt   2280

tatgcaagat tggaatgtat cttcaaattc agatttaata aacatgtaaa gatcctctgt   2340

atataaaagt tgtatttaat ccc                                           2363


<210>  7334
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  7334

Met Ser Lys Gly Gly Lys Arg Lys Asp Ser Val Trp Gly Ser Gly Gly 
1               5                   10                  15


Gly Gln Gln Ser Val Asn His Leu Val Lys Glu Ala Ile Ile Met Val 
            20                  25                  30


Leu Glu Ser Thr Gly Glu Ser Thr Phe Lys Met Ile Leu Asp Leu Leu 
        35                  40                  45


Lys Ser Leu Trp Lys Ser Ser Thr Ile Thr Val Asp Gln Met Lys Arg 
    50                  55                  60


Gly Tyr Glu Arg Ile Tyr Asn Glu Ile Pro Asp Ile Asn Leu Asp Val 
65                  70                  75                  80


Pro His Ser Tyr Ser Val Leu Glu Arg Phe Val Glu Glu Cys Phe Gln 
                85                  90                  95


Ala Gly Ile Ile Ser Lys Gln Leu Arg Asp Leu Cys Pro Ser Arg Gly 
            100                 105                 110


Arg Lys Arg Phe Val Ser Glu Gly Asp Gly Gly Arg Leu Lys Pro Glu 
        115                 120                 125


Ser Tyr 
    130


<210>  7335
<211>  1083
<212>  DNA
<213>  Homo sapiens

<400>  7335
ccttgccaat gtctgttatt tcctgactct aataaaagag aacagttgta aaacactgta     60

acaaatctac tttctgtgct tctcacgatt caaatctgac ttcagtttaa ccatttgaat    120

atttggcctt aaatacaaat tgatgacata gtgatggatt gtgttttatg acatttattt    180

tatatgggct aacaattctg catgtaattt cattgttgta gggttatgag agaatttaca    240

atgaaattcc ggacattaat ctggatgtcc cacattcata ctctgtgctg gagcggtttg    300

tagaagaatg ttttcaggct ggaataattt ccaaacaact cagagatctt tgtccttcaa    360

ggggcagaaa gcgttttgta agcgaaggag atggaggtcg tcttaaacca gagagctact    420

gaatataaga actcttgcag tcttagatgt tataaaaata tatatctgaa ttgtaagagt    480

tgttagcaca agtttttttt tttttttttt ttaagcactt gttttgggta caaggcattt    540

ctgacatttt ataaacctac atttaagggg aatttttaaa ggaaatgttt tttctttttt    600

ttttgttttt cgagggggca aggagggaca gaaaagtaac ctcttcttaa gtggaatatt    660

ctaataagct accttttgta agtgccatgt ttattatcta atcattccaa gttttgcatt    720

gatgtctgac tgccactcct ttctttcaag gacagtgttt tttgtagtaa aatcactggt    780

ttatacaaag ctttatttag ggggtaaagt taagctgcta aaaccccatg ttggctgctg    840

ctgttgagat actgtgcttt gggagtaaaa aaagaaagtt atttctttgt cttaaagaat    900

ttttaaaaaa ttagtcatga gacttattca tctttccagg gaacatactg attggtctta    960

aaagactaga cagttaagta aaaggtggct ggaacatcta tttttctaca aaactggaaa   1020

aatgaacctg gttctagaag aatgtacacc aaaataaaac atgtgaagca gtattgattc   1080

ttt                                                                 1083


<210>  7336
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7336

Met Phe Ser Gly Trp Asn Asn Phe Gln Thr Thr Gln Arg Ser Leu Ser 
1               5                   10                  15


Phe Lys Gly Gln Lys Ala Phe Cys Lys Arg Arg Arg Trp Arg Ser Ser 
            20                  25                  30


<210>  7337
<211>  1479
<212>  DNA
<213>  Homo sapiens

<400>  7337
ccttgccaat gtctgttatt tcctgactct aataaaagag aacagttgta aaacactgta     60

acaaatctac tttctgtgct tctcacgatt caaatctgac ttcagtttaa ccatttgaat    120

atttggcctt aaatacaaat tgatgacata gtgatggatt gtgttttatg acatttattt    180

tatatgggct aacaattctg catgtaattt cattgttgta gggttatgag agaatttaca    240

atgaaattcc ggacattaat ctggatgtcc cacattcata ctctgtgctg gagcggtttg    300

tagaagaatg ttttcaggct ggaataattt ccaaacaact cagagatctt tgtccttcaa    360

ggggcagaaa gcgttttgta agcgaaggag atggaggtcg tcttaaacca gagagctact    420

gaatataaga actcttgcag tcttagatgt tataaaaata tatatctgaa ttgtaagagt    480

tgttagcaca agtttttttt tttttttttt ttaagcactt gttttgggta caaggcattt    540

ctgacatttt ataaacctac atttaagggg aatttttaaa ggaaatgttt tttctttttt    600

ttttgttttt cgagggggca aggagggaca gaaaagtaac ctcttcttaa gtggaatatt    660

ctaataagct accttttgta agtgccatgt ttattatcta atcattccaa gttttgcatt    720

gatgtctgac tgccactcct ttctttcaag gacagtgttt tttgtagtaa aatcactggt    780

ttatacaaag ctttatttag ggggtaaagt taagctgcta aaaccccatg ttggctgctg    840

ctgttgagat actgtgcttt gggagtaaaa aaagaaagtt atttctttgt cttaaagaat    900

ttttaaaaaa ttagtcatga gacttattca tctttccagg gaacatactg attggtctta    960

aaagactaga cagttaagta aaaggtggct ggaacatcta tttttctaca aaactggaaa   1020

aatgaacctg gttctagaag aatgtacacc aaaataaaac atgtgaagca gtattgattc   1080

tttattggga gtacattttt ttaggtctct taaactttaa tttcacacag taaattttga   1140

atctcataag gaagcatatt tgaacctagt caatttaatc ttagtgttcc cttgaaaact   1200

ttttttccct acaaaatttt aagtgaaaaa tacaatagta aattaagatt acactgggga   1260

aaaaaatgca ggtatcactt tactccattg ttatctgacc tagagcttaa ttaagtttta   1320

gaaatatgta ataccttcca tcattccatc atccttaaat tctgttacca aataatggct   1380

aatgttacaa aaagttatac tccagagacc caaagcttga catttaccta atgtatgaga   1440

aaatattacc aattaacaat aaagaatgat catattttt                          1479


<210>  7338
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7338

Met Phe Ser Gly Trp Asn Asn Phe Gln Thr Thr Gln Arg Ser Leu Ser 
1               5                   10                  15


Phe Lys Gly Gln Lys Ala Phe Cys Lys Arg Arg Arg Trp Arg Ser Ser 
            20                  25                  30


<210>  7339
<211>  2339
<212>  DNA
<213>  Homo sapiens

<400>  7339
ccttgccaat gtctgttatt tcctgactct aataaaagag aacagttgta aaacactgta     60

acaaatctac tttctgtgct tctcacgatt caaatctgac ttcagtttaa ccatttgaat    120

atttggcctt aaatacaaat tgatgacata gtgatggatt gtgttttatg acatttattt    180

tatatgggct aacaattctg catgtaattt cattgttgta gggttatgag agaatttaca    240

atgaaattcc ggacattaat ctggatgtcc cacattcata ctctgtgctg gagcggtttg    300

tagaagaatg ttttcaggct ggaataattt ccaaacaact cagagatctt tgtccttcaa    360

ggggcagaaa gcgttttgta agcgaaggag atggaggtcg tcttaaacca gagagctact    420

gaatataaga actcttgcag tcttagatgt tataaaaata tatatctgaa ttgtaagagt    480

tgttagcaca agtttttttt tttttttttt ttaagcactt gttttgggta caaggcattt    540

ctgacatttt ataaacctac atttaagggg aatttttaaa ggaaatgttt tttctttttt    600

ttttgttttt cgagggggca aggagggaca gaaaagtaac ctcttcttaa gtggaatatt    660

ctaataagct accttttgta agtgccatgt ttattatcta atcattccaa gttttgcatt    720

gatgtctgac tgccactcct ttctttcaag gacagtgttt tttgtagtaa aatcactggt    780

ttatacaaag ctttatttag ggggtaaagt taagctgcta aaaccccatg ttggctgctg    840

ctgttgagat actgtgcttt gggagtaaaa aaagaaagtt atttctttgt cttaaagaat    900

ttttaaaaaa ttagtcatga gacttattca tctttccagg gaacatactg attggtctta    960

aaagactaga cagttaagta aaaggtggct ggaacatcta tttttctaca aaactggaaa   1020

aatgaacctg gttctagaag aatgtacacc aaaataaaac atgtgaagca gtattgattc   1080

tttattggga gtacattttt ttaggtctct taaactttaa tttcacacag taaattttga   1140

atctcataag gaagcatatt tgaacctagt caatttaatc ttagtgttcc cttgaaaact   1200

ttttttccct acaaaatttt aagtgaaaaa tacaatagta aattaagatt acactgggga   1260

aaaaaatgca ggtatcactt tactccattg ttatctgacc tagagcttaa ttaagtttta   1320

gaaatatgta ataccttcca tcattccatc atccttaaat tctgttacca aataatggct   1380

aatgttacaa aaagttatac tccagagacc caaagcttga catttaccta atgtatgaga   1440

aaatattacc aattaacaat aaagaatgat catattttta acctctttta catagcctaa   1500

taactcagca aggcctcaac gtctgtgcta atttaaactg ccaaatattg actgcagcaa   1560

acaagaatta tattcagaat ttatgagggt actgttagga gtatactgct tacaggttta   1620

gatatagtct gttagaatta aaaccaagtt tagtgttcat atttacctca tgggctttat   1680

caagcccata ttacctcagc ttatatatag ttaccatttt taggttttta attgtttgac   1740

acttggatga taaatgcagt cattttattc tcaagtgctt aaaattaatg taattaaaag   1800

cttagctgac tacagaatag gtgagggttt cttaaaaatg agatttaagg gctgggcacg   1860

gtggctcatg cctgtaatcc cagcactttg ggaggccgag gtgggcggat cacttgaggt   1920

tgggagttca tgaccagctt gaccaacatg aagaaaccct gtctctatta aaaatacaaa   1980

agtagccagg catggtggcg catgcgtgta atcccagcta cttgggaggc tgaggcagga   2040

gaattgcttg aacctgggag gcagaggttg cagtgagtcg agatggtgcc attgctctcg   2100

tttgggcaac aagagtgaaa ctcttgtctc aaaaaaaaaa aaaaatgagg tttaagacag   2160

ttttgtcatt actggtggga tctggtcaca caagatagca ttaaacgtga catggcacat   2220

aaaattggtt aaaaaatttt gttttttaat tacgtaatgt aaaagcccaa caaacacttt   2280

atgcaagatt ggaatgtatc ttcaaattca gatttaataa acatgtaaag atcctctgt    2339


<210>  7340
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7340

Met Phe Ser Gly Trp Asn Asn Phe Gln Thr Thr Gln Arg Ser Leu Ser 
1               5                   10                  15


Phe Lys Gly Gln Lys Ala Phe Cys Lys Arg Arg Arg Trp Arg Ser Ser 
            20                  25                  30


<210>  7341
<211>  2362
<212>  DNA
<213>  Homo sapiens

<400>  7341
ccttgccaat gtctgttatt tcctgactct aataaaagag aacagttgta aaacactgta     60

acaaatctac tttctgtgct tctcacgatt caaatctgac ttcagtttaa ccatttgaat    120

atttggcctt aaatacaaat tgatgacata gtgatggatt gtgttttatg acatttattt    180

tatatgggct aacaattctg catgtaattt cattgttgta gggttatgag agaatttaca    240

atgaaattcc ggacattaat ctggatgtcc cacattcata ctctgtgctg gagcggtttg    300

tagaagaatg ttttcaggct ggaataattt ccaaacaact cagagatctt tgtccttcaa    360

ggggcagaaa gcgttttgta agcgaaggag atggaggtcg tcttaaacca gagagctact    420

gaatataaga actcttgcag tcttagatgt tataaaaata tatatctgaa ttgtaagagt    480

tgttagcaca agtttttttt tttttttttt ttaagcactt gttttgggta caaggcattt    540

ctgacatttt ataaacctac atttaagggg aatttttaaa ggaaatgttt tttctttttt    600

ttttgttttt cgagggggca aggagggaca gaaaagtaac ctcttcttaa gtggaatatt    660

ctaataagct accttttgta agtgccatgt ttattatcta atcattccaa gttttgcatt    720

gatgtctgac tgccactcct ttctttcaag gacagtgttt tttgtagtaa aatcactggt    780

ttatacaaag ctttatttag ggggtaaagt taagctgcta aaaccccatg ttggctgctg    840

ctgttgagat actgtgcttt gggagtaaaa aaagaaagtt atttctttgt cttaaagaat    900

ttttaaaaaa ttagtcatga gacttattca tctttccagg gaacatactg attggtctta    960

aaagactaga cagttaagta aaaggtggct ggaacatcta tttttctaca aaactggaaa   1020

aatgaacctg gttctagaag aatgtacacc aaaataaaac atgtgaagca gtattgattc   1080

tttattggga gtacattttt ttaggtctct taaactttaa tttcacacag taaattttga   1140

atctcataag gaagcatatt tgaacctagt caatttaatc ttagtgttcc cttgaaaact   1200

ttttttccct acaaaatttt aagtgaaaaa tacaatagta aattaagatt acactgggga   1260

aaaaaatgca ggtatcactt tactccattg ttatctgacc tagagcttaa ttaagtttta   1320

gaaatatgta ataccttcca tcattccatc atccttaaat tctgttacca aataatggct   1380

aatgttacaa aaagttatac tccagagacc caaagcttga catttaccta atgtatgaga   1440

aaatattacc aattaacaat aaagaatgat catattttta acctctttta catagcctaa   1500

taactcagca aggcctcaac gtctgtgcta atttaaactg ccaaatattg actgcagcaa   1560

acaagaatta tattcagaat ttatgagggt actgttagga gtatactgct tacaggttta   1620

gatatagtct gttagaatta aaaccaagtt tagtgttcat atttacctca tgggctttat   1680

caagcccata ttacctcagc ttatatatag ttaccatttt taggttttta attgtttgac   1740

acttggatga taaatgcagt cattttattc tcaagtgctt aaaattaatg taattaaaag   1800

cttagctgac tacagaatag gtgagggttt cttaaaaatg agatttaagg gctgggcacg   1860

gtggctcatg cctgtaatcc cagcactttg ggaggccgag gtgggcggat cacttgaggt   1920

tgggagttca tgaccagctt gaccaacatg aagaaaccct gtctctatta aaaatacaaa   1980

agtagccagg catggtggcg catgcgtgta atcccagcta cttgggaggc tgaggcagga   2040

gaattgcttg aacctgggag gcagaggttg cagtgagtcg agatggtgcc attgctctcg   2100

tttgggcaac aagagtgaaa ctcttgtctc aaaaaaaaaa aaaaatgagg tttaagacag   2160

ttttgtcatt actggtggga tctggtcaca caagatagca ttaaacgtga catggcacat   2220

aaaattggtt aaaaaatttt gttttttaat tacgtaatgt aaaagcccaa caaacacttt   2280

atgcaagatt ggaatgtatc ttcaaattca gatttaataa acatgtaaag atcctctgta   2340

tataaaagtt gtatttaatc cc                                            2362


<210>  7342
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  7342

Met Phe Ser Gly Trp Asn Asn Phe Gln Thr Thr Gln Arg Ser Leu Ser 
1               5                   10                  15


Phe Lys Gly Gln Lys Ala Phe Cys Lys Arg Arg Arg Trp Arg Ser Ser 
            20                  25                  30


<210>  7343
<211>  2761
<212>  DNA
<213>  Homo sapiens

<400>  7343
acttccgaat tgggtcatgg cggaagggtg ttaatagcct ggccgcccgt gccccaggga     60

atgcttattt ttgaccttag ttgcaaagtg agtttcttct gtatgcttga gtcaagaact    120

ctaagtcatc ttggtaatac cgggttggat gcttaaagct gcagcaaaaa gaccagaact    180

ttcaggaaaa aacactatat ccaacaactc agatatggca gaagtgaagt caatgttccg    240

ggaagttctt ccaaagcaag ggccactgtt tgtggaagat ataatgacaa tggtgctgtg    300

taaacccaaa cttttaccct taaaatctct gactctggaa aaactagaga aaatgcatca    360

agcagcacag aatacaattc gccaacaaga aatggcagaa aaggatcaac ggcaaataac    420

ccactgaatg ataactgagc actttaggga acaacctgcc ttatctacta tttaacaata    480

actagaaaat atgcttctgt gtgctgaaag tagtatgtgt tatcaataaa attgatagta    540

ttcatagaaa tacaaaaata tccaagattg atgaaatttg tattgtgaat gtaaacactc    600

tggtttgtat tgaacataaa cagttaaact atgaaccaag ttttatgggg tttaagtcat    660

gtttttagaa ttgcaaatta aattatttgt tcaccattcc tattgctatc ttttatagat    720

aacattcttg ggatctttta tagcattctt gggcacaagg gattaaatac aacttttata    780

tacagaggat ctttacatgt ttattaaatc tgaatttgaa gatacattcc aatcttgcat    840

aaagtgtttg ttgggctttt acattacgta attaaaaaac aaaatttttt aaccaatttt    900

atgtgccatg tcacgtttaa tgctatcttg tgtgaccaga tcccaccagt aatgacaaaa    960

ctgtcttaaa cctcattttt tttttttttt gagacaagag tttcactctt gttgcccaaa   1020

cgagagcaat ggcaccatct cgactcactg caacctctgc ctcccaggtt caagcaattc   1080

tcctgcctca gcctcccaag tagctgggat tacacgcatg cgccaccatg cctggctact   1140

tttgtatttt taatagagac agggtttctt catgttggtc aagctggtca tgaactccca   1200

acctcaagtg atccgcccac ctcggcctcc caaagtgctg ggattacagg catgagccac   1260

cgtgcccagc ccttaaatct catttttaag aaaccctcac ctattctgta gtcagctaag   1320

cttttaatta cattaatttt aagcacttga gaataaaatg actgcattta tcatccaagt   1380

gtcaaacaat taaaaaccta aaaatggtaa ctatatataa gctgaggtaa tatgggcttg   1440

ataaagccca tgaggtaaat atgaacacta aacttggttt taattctaac agactatatc   1500

taaacctgta agcagtatac tcctaacagt accctcataa attctgaata taattcttgt   1560

ttgctgcagt caatatttgg cagtttaaat tagcacagac gttgaggcct tgctgagtta   1620

ttaggctatg taaaagaggt taaaaatatg atcattcttt attgttaatt ggtaatattt   1680

tctcatacat taggtaaatg tcaagctttg ggtctctgga gtataacttt ttgtaacatt   1740

agccattatt tggtaacaga atttaaggat gatggaatga tggaaggtat tacatatttc   1800

taaaacttaa ttaagctcta ggtcagataa caatggagta aagtgatacc tgcatttttt   1860

tccccagtgt aatcttaatt tactattgta tttttcactt aaaattttgt agggaaaaaa   1920

agttttcaag ggaacactaa gattaaattg actaggttca aatatgcttc cttatgagat   1980

tcaaaattta ctgtgtgaaa ttaaagttta agagacctaa aaaaatgtac tcccaataaa   2040

gaatcaatac tgcttcacat gttttatttt ggtgtacatt cttctagaac caggttcatt   2100

tttccagttt tgtagaaaaa tagatgttcc agccaccttt tacttaactg tctagtcttt   2160

taagaccaat cagtatgttc cctggaaaga tgaataagtc tcatgactaa ttttttaaaa   2220

attctttaag acaaagaaat aactttcttt ttttactccc aaagcacagt atctcaacag   2280

cagcagccaa catggggttt tagcagctta actttacccc ctaaataaag ctttgtataa   2340

accagtgatt ttactacaaa aaacactgtc cttgaaagaa aggagtggca gtcagacatc   2400

aatgcaaaac ttggaatgat tagataataa acatggcact tacaaaaggt agcttattag   2460

aatattccac ttaagaagag gttacttttc tgtccctcct tgccccctcg aaaaacaaaa   2520

aaaaaagaaa aaacatttcc tttaaaaatt ccccttaaat gtaggtttat aaaatgtcag   2580

aaatgccttg tacccaaaac aagtgcttaa aaaaaaaaaa aaaaaaaact tgtgctaaca   2640

actcttacaa ttcagatata tatttttata acatctaaga ctgcaagagt tcttatattc   2700

agtagctctc tggtttaaga cgacctccat ctccttcgct tacaaaacgc tttctgcccc   2760

t                                                                   2761


<210>  7344
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7344

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7345
<211>  3741
<212>  DNA
<213>  Homo sapiens

<400>  7345
ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc     60

ttttcttctg tatgcttgag tcaagaactc taagtcatct tggtaatacc gggttggatg    120

cttaaagctg cagcaaaaag accagaactt tcaggaaaaa acactatatc caacaactca    180

gatatggcag aagtgaagtc aatgttccgg gaagttcttc caaagcaagg tatgtacatc    240

acaaatattg aggtcattga ttattacagg actaaagaag tcataggcag tgtcacatag    300

caggcttaat agctaaacat ctgcagctat tgtgttccgt attatctcat ttactgtctt    360

ttactatatg ctttttcatg acatccagta aaaggataac aaatgaaaca ttgtttctta    420

tacctaaaat tgcctattaa ttagctaatt cctaaaattc ctaattacaa tatgaatttt    480

ttttaagaga caggttgtca ctctgccacc caggcttggg tacagctggc acaaccgtag    540

ctcaccgcag ccttgaacta ctgggctcct gccctagcct actgatttgc tagtactaca    600

ggcatgtgct accatgcctg gctaatttgt tcttattttt gtagagaagg gatctcaatg    660

tgttgcctag gctggtctca aacccctggg ctcaaacaaa caatccaacc cctttggcat    720

cccaaagtgc tgggataaca ggtaagagct accatgccct actcaatatg aaacttcagt    780

gaaagaaata atggaattta ctatgttaaa taaggtctga aagtggagaa agagaaacct    840

gaagcaacag taagaaaagc cgaaggttta aaccttcagt catttgaata tttacgttaa    900

atatcatatt ttgctatatt tttttgcact atgtatatat atattctgcc aaatcttatt    960

ttaagattaa acttctgaca caaaaagttg tgtcttatgg tagcatagat tcttgggtag   1020

aacgctcaaa acttgtcttc ctcagaagca ccctactagt aagaaatgcg cttatagaat   1080

gacaatgatc tttctggttc cagagcaaaa ctcaatttag gtacaagagt ttttcagtga   1140

caagagatta attttttaga ccttcattct agctgcaaat ccaactacaa acaactgggt   1200

tatctttctt gaattaattc ttatttcttg ttaaacttag ggccactgtt tgtggaagat   1260

ataatgacaa tggtgctgtg taaacccaaa cttttaccct taaaatctct gactctggaa   1320

aaactagaga aaatgcatca agcagcacag aatacaattc gccaacaaga aatggcagaa   1380

aaggatcaac ggcaaataac ccactgaatg ataactgagc actttaggga acaacctgcc   1440

ttatctacta tttaacaata actagaaaat atgcttctgt gtgctgaaag tagtatgtgt   1500

tatcaataaa attgatagta ttcatagaaa tacaaaaata tccaagattg atgaaatttg   1560

tattgtgaat gtaaacactc tggtttgtat tgaacataaa cagttaaact atgaaccaag   1620

ttttatgggg tttaagtcat gtttttagaa ttgcaaatta aattatttgt tcaccattcc   1680

tattgctatc ttttatagat aacattcttg ggatctttta tagcattctt gggcacaagg   1740

gattaaatac aacttttata tacagaggat ctttacatgt ttattaaatc tgaatttgaa   1800

gatacattcc aatcttgcat aaagtgtttg ttgggctttt acattacgta attaaaaaac   1860

aaaatttttt aaccaatttt atgtgccatg tcacgtttaa tgctatcttg tgtgaccaga   1920

tcccaccagt aatgacaaaa ctgtcttaaa cctcattttt tttttttttt gagacaagag   1980

tttcactctt gttgcccaaa cgagagcaat ggcaccatct cgactcactg caacctctgc   2040

ctcccaggtt caagcaattc tcctgcctca gcctcccaag tagctgggat tacacgcatg   2100

cgccaccatg cctggctact tttgtatttt taatagagac agggtttctt catgttggtc   2160

aagctggtca tgaactccca acctcaagtg atccgcccac ctcggcctcc caaagtgctg   2220

ggattacagg catgagccac cgtgcccagc ccttaaatct catttttaag aaaccctcac   2280

ctattctgta gtcagctaag cttttaatta cattaatttt aagcacttga gaataaaatg   2340

actgcattta tcatccaagt gtcaaacaat taaaaaccta aaaatggtaa ctatatataa   2400

gctgaggtaa tatgggcttg ataaagccca tgaggtaaat atgaacacta aacttggttt   2460

taattctaac agactatatc taaacctgta agcagtatac tcctaacagt accctcataa   2520

attctgaata taattcttgt ttgctgcagt caatatttgg cagtttaaat tagcacagac   2580

gttgaggcct tgctgagtta ttaggctatg taaaagaggt taaaaatatg atcattcttt   2640

attgttaatt ggtaatattt tctcatacat taggtaaatg tcaagctttg ggtctctgga   2700

gtataacttt ttgtaacatt agccattatt tggtaacaga atttaaggat gatggaatga   2760

tggaaggtat tacatatttc taaaacttaa ttaagctcta ggtcagataa caatggagta   2820

aagtgatacc tgcatttttt tccccagtgt aatcttaatt tactattgta tttttcactt   2880

aaaattttgt agggaaaaaa agttttcaag ggaacactaa gattaaattg actaggttca   2940

aatatgcttc cttatgagat tcaaaattta ctgtgtgaaa ttaaagttta agagacctaa   3000

aaaaatgtac tcccaataaa gaatcaatac tgcttcacat gttttatttt ggtgtacatt   3060

cttctagaac caggttcatt tttccagttt tgtagaaaaa tagatgttcc agccaccttt   3120

tacttaactg tctagtcttt taagaccaat cagtatgttc cctggaaaga tgaataagtc   3180

tcatgactaa ttttttaaaa attctttaag acaaagaaat aactttcttt ttttactccc   3240

aaagcacagt atctcaacag cagcagccaa catggggttt tagcagctta actttacccc   3300

ctaaataaag ctttgtataa accagtgatt ttactacaaa aaacactgtc cttgaaagaa   3360

aggagtggca gtcagacatc aatgcaaaac ttggaatgat tagataataa acatggcact   3420

tacaaaaggt agcttattag aatattccac ttaagaagag gttacttttc tgtccctcct   3480

tgccccctcg aaaaacaaaa aaaaaagaaa aaacatttcc tttaaaaatt ccccttaaat   3540

gtaggtttat aaaatgtcag aaatgccttg tacccaaaac aagtgcttaa aaaaaaaaaa   3600

aaaaaaaact tgtgctaaca actcttacaa ttcagatata tatttttata acatctaaga   3660

ctgcaagagt tcttatattc agtagctctc tggtttaaga cgacctccat ctccttcgct   3720

tacaaaacgc tttctgcccc t                                             3741


<210>  7346
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  7346

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Met Tyr Ile Thr Asn Ile Glu Val Ile Asp 
        35                  40                  45


Tyr Tyr Arg Thr Lys Glu Val Ile Gly Ser Val Thr 
    50                  55                  60


<210>  7347
<211>  2828
<212>  DNA
<213>  Homo sapiens

<400>  7347
tccttcgcca gtctcaccgt tacccggggc aacagctgag ccgtctggga agggatgcat     60

cttttcttct gtatgcttga gtcaagaact ctaagtcatc ttggtaatac cgggttggat    120

gcttaaagct gcagcaaaaa gaccagaact ttcaggaaaa aacactatat ccaacaactc    180

agatatggca gaagtgaagt caatgttccg ggaagttctt ccaaagcaag agaagggatc    240

tcaatgtgtt gcctaggctg gtctcaaacc cctgggctca aacaaacaat ccaacccctt    300

tggcatccca aagtgctggg ataacagggc cactgtttgt ggaagatata atgacaatgg    360

tgctgtgtaa acccaaactt ttacccttaa aatctctgac tctggaaaaa ctagagaaaa    420

tgcatcaagc agcacagaat acaattcgcc aacaagaaat ggcagaaaag gatcaacggc    480

aaataaccca ctgaatgata actgagcact ttagggaaca acctgcctta tctactattt    540

aacaataact agaaaatatg cttctgtgtg ctgaaagtag tatgtgttat caataaaatt    600

gatagtattc atagaaatac aaaaatatcc aagattgatg aaatttgtat tgtgaatgta    660

aacactctgg tttgtattga acataaacag ttaaactatg aaccaagttt tatggggttt    720

aagtcatgtt tttagaattg caaattaaat tatttgttca ccattcctat tgctatcttt    780

tatagataac attcttggga tcttttatag cattcttggg cacaagggat taaatacaac    840

ttttatatac agaggatctt tacatgttta ttaaatctga atttgaagat acattccaat    900

cttgcataaa gtgtttgttg ggcttttaca ttacgtaatt aaaaaacaaa attttttaac    960

caattttatg tgccatgtca cgtttaatgc tatcttgtgt gaccagatcc caccagtaat   1020

gacaaaactg tcttaaacct catttttttt tttttttgag acaagagttt cactcttgtt   1080

gcccaaacga gagcaatggc accatctcga ctcactgcaa cctctgcctc ccaggttcaa   1140

gcaattctcc tgcctcagcc tcccaagtag ctgggattac acgcatgcgc caccatgcct   1200

ggctactttt gtatttttaa tagagacagg gtttcttcat gttggtcaag ctggtcatga   1260

actcccaacc tcaagtgatc cgcccacctc ggcctcccaa agtgctggga ttacaggcat   1320

gagccaccgt gcccagccct taaatctcat ttttaagaaa ccctcaccta ttctgtagtc   1380

agctaagctt ttaattacat taattttaag cacttgagaa taaaatgact gcatttatca   1440

tccaagtgtc aaacaattaa aaacctaaaa atggtaacta tatataagct gaggtaatat   1500

gggcttgata aagcccatga ggtaaatatg aacactaaac ttggttttaa ttctaacaga   1560

ctatatctaa acctgtaagc agtatactcc taacagtacc ctcataaatt ctgaatataa   1620

ttcttgtttg ctgcagtcaa tatttggcag tttaaattag cacagacgtt gaggccttgc   1680

tgagttatta ggctatgtaa aagaggttaa aaatatgatc attctttatt gttaattggt   1740

aatattttct catacattag gtaaatgtca agctttgggt ctctggagta taactttttg   1800

taacattagc cattatttgg taacagaatt taaggatgat ggaatgatgg aaggtattac   1860

atatttctaa aacttaatta agctctaggt cagataacaa tggagtaaag tgatacctgc   1920

atttttttcc ccagtgtaat cttaatttac tattgtattt ttcacttaaa attttgtagg   1980

gaaaaaaagt tttcaaggga acactaagat taaattgact aggttcaaat atgcttcctt   2040

atgagattca aaatttactg tgtgaaatta aagtttaaga gacctaaaaa aatgtactcc   2100

caataaagaa tcaatactgc ttcacatgtt ttattttggt gtacattctt ctagaaccag   2160

gttcattttt ccagttttgt agaaaaatag atgttccagc caccttttac ttaactgtct   2220

agtcttttaa gaccaatcag tatgttccct ggaaagatga ataagtctca tgactaattt   2280

tttaaaaatt ctttaagaca aagaaataac tttctttttt tactcccaaa gcacagtatc   2340

tcaacagcag cagccaacat ggggttttag cagcttaact ttacccccta aataaagctt   2400

tgtataaacc agtgatttta ctacaaaaaa cactgtcctt gaaagaaagg agtggcagtc   2460

agacatcaat gcaaaacttg gaatgattag ataataaaca tggcacttac aaaaggtagc   2520

ttattagaat attccactta agaagaggtt acttttctgt ccctccttgc cccctcgaaa   2580

aacaaaaaaa aaagaaaaaa catttccttt aaaaattccc cttaaatgta ggtttataaa   2640

atgtcagaaa tgccttgtac ccaaaacaag tgcttaaaaa aaaaaaaaaa aaaaacttgt   2700

gctaacaact cttacaattc agatatatat ttttataaca tctaagactg caagagttct   2760

tatattcagt agctctctgg tttaagacga cctccatctc cttcgcttac aaaacgcttt   2820

ctgcccct                                                            2828


<210>  7348
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  7348

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Glu Lys Gly Ser Gln Cys Val Ala 
        35                  40                  45


<210>  7349
<211>  2667
<212>  DNA
<213>  Homo sapiens

<400>  7349
gtagattttt ttccttcgcc agtctcaccg ttacccgggg caacagctga gccgtctggg     60

aagggatgca tcttttcttc tgtatgcttg agtcaagaac tctaagtcat cttggtaata    120

ccgggttgga tgcttaaagc tgcagcaaaa agaccagaac tttcagggcc actgtttgtg    180

gaagatataa tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact    240

ctggaaaaac tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg    300

gcagaaaagg atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa    360

cctgccttat ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt    420

atgtgttatc aataaaattg atagtattca tagaaataca aaaatatcca agattgatga    480

aatttgtatt gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga    540

accaagtttt atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac    600

cattcctatt gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc    660

acaagggatt aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa    720

tttgaagata cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta    780

aaaaacaaaa ttttttaacc aattttatgt gccatgtcac gtttaatgct atcttgtgtg    840

accagatccc accagtaatg acaaaactgt cttaaacctc attttttttt ttttttgaga    900

caagagtttc actcttgttg cccaaacgag agcaatggca ccatctcgac tcactgcaac    960

ctctgcctcc caggttcaag caattctcct gcctcagcct cccaagtagc tgggattaca   1020

cgcatgcgcc accatgcctg gctacttttg tatttttaat agagacaggg tttcttcatg   1080

ttggtcaagc tggtcatgaa ctcccaacct caagtgatcc gcccacctcg gcctcccaaa   1140

gtgctgggat tacaggcatg agccaccgtg cccagccctt aaatctcatt tttaagaaac   1200

cctcacctat tctgtagtca gctaagcttt taattacatt aattttaagc acttgagaat   1260

aaaatgactg catttatcat ccaagtgtca aacaattaaa aacctaaaaa tggtaactat   1320

atataagctg aggtaatatg ggcttgataa agcccatgag gtaaatatga acactaaact   1380

tggttttaat tctaacagac tatatctaaa cctgtaagca gtatactcct aacagtaccc   1440

tcataaattc tgaatataat tcttgtttgc tgcagtcaat atttggcagt ttaaattagc   1500

acagacgttg aggccttgct gagttattag gctatgtaaa agaggttaaa aatatgatca   1560

ttctttattg ttaattggta atattttctc atacattagg taaatgtcaa gctttgggtc   1620

tctggagtat aactttttgt aacattagcc attatttggt aacagaattt aaggatgatg   1680

gaatgatgga aggtattaca tatttctaaa acttaattaa gctctaggtc agataacaat   1740

ggagtaaagt gatacctgca tttttttccc cagtgtaatc ttaatttact attgtatttt   1800

tcacttaaaa ttttgtaggg aaaaaaagtt ttcaagggaa cactaagatt aaattgacta   1860

ggttcaaata tgcttcctta tgagattcaa aatttactgt gtgaaattaa agtttaagag   1920

acctaaaaaa atgtactccc aataaagaat caatactgct tcacatgttt tattttggtg   1980

tacattcttc tagaaccagg ttcatttttc cagttttgta gaaaaataga tgttccagcc   2040

accttttact taactgtcta gtcttttaag accaatcagt atgttccctg gaaagatgaa   2100

taagtctcat gactaatttt ttaaaaattc tttaagacaa agaaataact ttcttttttt   2160

actcccaaag cacagtatct caacagcagc agccaacatg gggttttagc agcttaactt   2220

taccccctaa ataaagcttt gtataaacca gtgattttac tacaaaaaac actgtccttg   2280

aaagaaagga gtggcagtca gacatcaatg caaaacttgg aatgattaga taataaacat   2340

ggcacttaca aaaggtagct tattagaata ttccacttaa gaagaggtta cttttctgtc   2400

cctccttgcc ccctcgaaaa acaaaaaaaa aagaaaaaac atttccttta aaaattcccc   2460

ttaaatgtag gtttataaaa tgtcagaaat gccttgtacc caaaacaagt gcttaaaaaa   2520

aaaaaaaaaa aaaacttgtg ctaacaactc ttacaattca gatatatatt tttataacat   2580

ctaagactgc aagagttctt atattcagta gctctctggt ttaagacgac ctccatctcc   2640

ttcgcttaca aaacgctttc tgcccct                                       2667


<210>  7350
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7350

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Pro Leu Phe 
1               5                   10                  15


Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys Leu Leu Pro 
            20                  25                  30


Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His Gln Ala Ala 
        35                  40                  45


Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp Gln Arg Gln 
    50                  55                  60


Ile Thr His 
65


<210>  7351
<211>  2657
<212>  DNA
<213>  Homo sapiens

<400>  7351
agggtgacgt agattttttt ccttcgccag tctcaccgtt acccggggca acagctgagc     60

cgtctgggaa gggatgcatc tgaaaaaaca ctatatccaa caactcagat atggcagaag    120

tgaagtcaat gttccgggaa gttcttccaa agcaagggcc actgtttgtg gaagatataa    180

tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact ctggaaaaac    240

tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg gcagaaaagg    300

atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa cctgccttat    360

ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt atgtgttatc    420

aataaaattg atagtattca tagaaataca aaaatatcca agattgatga aatttgtatt    480

gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga accaagtttt    540

atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac cattcctatt    600

gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc acaagggatt    660

aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa tttgaagata    720

cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta aaaaacaaaa    780

ttttttaacc aattttatgt gccatgtcac gtttaatgct atcttgtgtg accagatccc    840

accagtaatg acaaaactgt cttaaacctc attttttttt ttttttgaga caagagtttc    900

actcttgttg cccaaacgag agcaatggca ccatctcgac tcactgcaac ctctgcctcc    960

caggttcaag caattctcct gcctcagcct cccaagtagc tgggattaca cgcatgcgcc   1020

accatgcctg gctacttttg tatttttaat agagacaggg tttcttcatg ttggtcaagc   1080

tggtcatgaa ctcccaacct caagtgatcc gcccacctcg gcctcccaaa gtgctgggat   1140

tacaggcatg agccaccgtg cccagccctt aaatctcatt tttaagaaac cctcacctat   1200

tctgtagtca gctaagcttt taattacatt aattttaagc acttgagaat aaaatgactg   1260

catttatcat ccaagtgtca aacaattaaa aacctaaaaa tggtaactat atataagctg   1320

aggtaatatg ggcttgataa agcccatgag gtaaatatga acactaaact tggttttaat   1380

tctaacagac tatatctaaa cctgtaagca gtatactcct aacagtaccc tcataaattc   1440

tgaatataat tcttgtttgc tgcagtcaat atttggcagt ttaaattagc acagacgttg   1500

aggccttgct gagttattag gctatgtaaa agaggttaaa aatatgatca ttctttattg   1560

ttaattggta atattttctc atacattagg taaatgtcaa gctttgggtc tctggagtat   1620

aactttttgt aacattagcc attatttggt aacagaattt aaggatgatg gaatgatgga   1680

aggtattaca tatttctaaa acttaattaa gctctaggtc agataacaat ggagtaaagt   1740

gatacctgca tttttttccc cagtgtaatc ttaatttact attgtatttt tcacttaaaa   1800

ttttgtaggg aaaaaaagtt ttcaagggaa cactaagatt aaattgacta ggttcaaata   1860

tgcttcctta tgagattcaa aatttactgt gtgaaattaa agtttaagag acctaaaaaa   1920

atgtactccc aataaagaat caatactgct tcacatgttt tattttggtg tacattcttc   1980

tagaaccagg ttcatttttc cagttttgta gaaaaataga tgttccagcc accttttact   2040

taactgtcta gtcttttaag accaatcagt atgttccctg gaaagatgaa taagtctcat   2100

gactaatttt ttaaaaattc tttaagacaa agaaataact ttcttttttt actcccaaag   2160

cacagtatct caacagcagc agccaacatg gggttttagc agcttaactt taccccctaa   2220

ataaagcttt gtataaacca gtgattttac tacaaaaaac actgtccttg aaagaaagga   2280

gtggcagtca gacatcaatg caaaacttgg aatgattaga taataaacat ggcacttaca   2340

aaaggtagct tattagaata ttccacttaa gaagaggtta cttttctgtc cctccttgcc   2400

ccctcgaaaa acaaaaaaaa aagaaaaaac atttccttta aaaattcccc ttaaatgtag   2460

gtttataaaa tgtcagaaat gccttgtacc caaaacaagt gcttaaaaaa aaaaaaaaaa   2520

aaaacttgtg ctaacaactc ttacaattca gatatatatt tttataacat ctaagactgc   2580

aagagttctt atattcagta gctctctggt ttaagacgac ctccatctcc ttcgcttaca   2640

aaacgctttc tgcccct                                                  2657


<210>  7352
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7352

Met Ala Glu Val Lys Ser Met Phe Arg Glu Val Leu Pro Lys Gln Gly 
1               5                   10                  15


Pro Leu Phe Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys 
            20                  25                  30


Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His 
        35                  40                  45


Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp 
    50                  55                  60


Gln Arg Gln Ile Thr His 
65                  70


<210>  7353
<211>  2915
<212>  DNA
<213>  Homo sapiens

<400>  7353
ctgtttccag ggtgacgtag atttttttcc ttcgccagtc tcaccgttac ccggggcaac     60

agctgagccg tctgggaagg gatgcatctt ttcttctgta tgcttgagtc aagaactcta    120

agtcatcttg gtaataccgg gttggatgct taaagctgca gcaaaaagac cagaactttc    180

agggcttctc aaatttaata actatggaat cttatcagaa agtccattaa catctcaaag    240

aacaacgtgg ttattgtatc aatcaccatc ctttatacca ggatttgcat atccttcaag    300

atgcctgaag acaatcggag gggtatacaa gcaagcgagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaaccaa ttttatgtgc catgtcacgt ttaatgctat   1080

cttgtgtgac cagatcccac cagtaatgac aaaactgtct taaacctcat tttttttttt   1140

ttttgagaca agagtttcac tcttgttgcc caaacgagag caatggcacc atctcgactc   1200

actgcaacct ctgcctccca ggttcaagca attctcctgc ctcagcctcc caagtagctg   1260

ggattacacg catgcgccac catgcctggc tacttttgta tttttaatag agacagggtt   1320

tcttcatgtt ggtcaagctg gtcatgaact cccaacctca agtgatccgc ccacctcggc   1380

ctcccaaagt gctgggatta caggcatgag ccaccgtgcc cagcccttaa atctcatttt   1440

taagaaaccc tcacctattc tgtagtcagc taagctttta attacattaa ttttaagcac   1500

ttgagaataa aatgactgca tttatcatcc aagtgtcaaa caattaaaaa cctaaaaatg   1560

gtaactatat ataagctgag gtaatatggg cttgataaag cccatgaggt aaatatgaac   1620

actaaacttg gttttaattc taacagacta tatctaaacc tgtaagcagt atactcctaa   1680

cagtaccctc ataaattctg aatataattc ttgtttgctg cagtcaatat ttggcagttt   1740

aaattagcac agacgttgag gccttgctga gttattaggc tatgtaaaag aggttaaaaa   1800

tatgatcatt ctttattgtt aattggtaat attttctcat acattaggta aatgtcaagc   1860

tttgggtctc tggagtataa ctttttgtaa cattagccat tatttggtaa cagaatttaa   1920

ggatgatgga atgatggaag gtattacata tttctaaaac ttaattaagc tctaggtcag   1980

ataacaatgg agtaaagtga tacctgcatt tttttcccca gtgtaatctt aatttactat   2040

tgtatttttc acttaaaatt ttgtagggaa aaaaagtttt caagggaaca ctaagattaa   2100

attgactagg ttcaaatatg cttccttatg agattcaaaa tttactgtgt gaaattaaag   2160

tttaagagac ctaaaaaaat gtactcccaa taaagaatca atactgcttc acatgtttta   2220

ttttggtgta cattcttcta gaaccaggtt catttttcca gttttgtaga aaaatagatg   2280

ttccagccac cttttactta actgtctagt cttttaagac caatcagtat gttccctgga   2340

aagatgaata agtctcatga ctaatttttt aaaaattctt taagacaaag aaataacttt   2400

ctttttttac tcccaaagca cagtatctca acagcagcag ccaacatggg gttttagcag   2460

cttaacttta ccccctaaat aaagctttgt ataaaccagt gattttacta caaaaaacac   2520

tgtccttgaa agaaaggagt ggcagtcaga catcaatgca aaacttggaa tgattagata   2580

ataaacatgg cacttacaaa aggtagctta ttagaatatt ccacttaaga agaggttact   2640

tttctgtccc tccttgcccc ctcgaaaaac aaaaaaaaaa gaaaaaacat ttcctttaaa   2700

aattcccctt aaatgtaggt ttataaaatg tcagaaatgc cttgtaccca aaacaagtgc   2760

ttaaaaaaaa aaaaaaaaaa aacttgtgct aacaactctt acaattcaga tatatatttt   2820

tataacatct aagactgcaa gagttcttat attcagtagc tctctggttt aagacgacct   2880

ccatctcctt cgcttacaaa acgctttctg cccct                              2915


<210>  7354
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  7354

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Leu Leu Lys 
1               5                   10                  15


Phe Asn Asn Tyr Gly Ile Leu Ser Glu Ser Pro Leu Thr Ser Gln Arg 
            20                  25                  30


Thr Thr Trp Leu Leu Tyr Gln Ser Pro Ser Phe Ile Pro Gly Phe Ala 
        35                  40                  45


Tyr Pro Ser Arg Cys Leu Lys Thr Ile Gly Gly Val Tyr Lys Gln Ala 
    50                  55                  60


Arg Lys Lys His Tyr Ile Gln Gln Leu Arg Tyr Gly Arg Ser Glu Val 
65                  70                  75                  80


Asn Val Pro Gly Ser Ser Ser Lys Ala Arg Ala Thr Val Cys Gly Arg 
                85                  90                  95


Tyr Asn Asp Asn Gly Ala Val 
            100


<210>  7355
<211>  2915
<212>  DNA
<213>  Homo sapiens

<400>  7355
agttcctcta cgccgtctcc cgcccactgg gcgcctctgg ctagccgggc tacagagtaa     60

gcctccagca gggtagagtg acaactcccc gatcggaagt tactgttgaa gctaaggcgg    120

ccataactga taatggcaaa aggagattcc tggcttcctg tttccagggt gacgtagatt    180

tttttccttc gccagtctca ccgttacccg gggcaacagc tgagccgtct gggaagggat    240

gcatcttttc ttctgtatgc ttgagtcaag aactctaagt catcttggta ataccgggtt    300

ggatgcttaa agctgcagca aaaagaccag aactttcagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaaccaa ttttatgtgc catgtcacgt ttaatgctat   1080

cttgtgtgac cagatcccac cagtaatgac aaaactgtct taaacctcat tttttttttt   1140

ttttgagaca agagtttcac tcttgttgcc caaacgagag caatggcacc atctcgactc   1200

actgcaacct ctgcctccca ggttcaagca attctcctgc ctcagcctcc caagtagctg   1260

ggattacacg catgcgccac catgcctggc tacttttgta tttttaatag agacagggtt   1320

tcttcatgtt ggtcaagctg gtcatgaact cccaacctca agtgatccgc ccacctcggc   1380

ctcccaaagt gctgggatta caggcatgag ccaccgtgcc cagcccttaa atctcatttt   1440

taagaaaccc tcacctattc tgtagtcagc taagctttta attacattaa ttttaagcac   1500

ttgagaataa aatgactgca tttatcatcc aagtgtcaaa caattaaaaa cctaaaaatg   1560

gtaactatat ataagctgag gtaatatggg cttgataaag cccatgaggt aaatatgaac   1620

actaaacttg gttttaattc taacagacta tatctaaacc tgtaagcagt atactcctaa   1680

cagtaccctc ataaattctg aatataattc ttgtttgctg cagtcaatat ttggcagttt   1740

aaattagcac agacgttgag gccttgctga gttattaggc tatgtaaaag aggttaaaaa   1800

tatgatcatt ctttattgtt aattggtaat attttctcat acattaggta aatgtcaagc   1860

tttgggtctc tggagtataa ctttttgtaa cattagccat tatttggtaa cagaatttaa   1920

ggatgatgga atgatggaag gtattacata tttctaaaac ttaattaagc tctaggtcag   1980

ataacaatgg agtaaagtga tacctgcatt tttttcccca gtgtaatctt aatttactat   2040

tgtatttttc acttaaaatt ttgtagggaa aaaaagtttt caagggaaca ctaagattaa   2100

attgactagg ttcaaatatg cttccttatg agattcaaaa tttactgtgt gaaattaaag   2160

tttaagagac ctaaaaaaat gtactcccaa taaagaatca atactgcttc acatgtttta   2220

ttttggtgta cattcttcta gaaccaggtt catttttcca gttttgtaga aaaatagatg   2280

ttccagccac cttttactta actgtctagt cttttaagac caatcagtat gttccctgga   2340

aagatgaata agtctcatga ctaatttttt aaaaattctt taagacaaag aaataacttt   2400

ctttttttac tcccaaagca cagtatctca acagcagcag ccaacatggg gttttagcag   2460

cttaacttta ccccctaaat aaagctttgt ataaaccagt gattttacta caaaaaacac   2520

tgtccttgaa agaaaggagt ggcagtcaga catcaatgca aaacttggaa tgattagata   2580

ataaacatgg cacttacaaa aggtagctta ttagaatatt ccacttaaga agaggttact   2640

tttctgtccc tccttgcccc ctcgaaaaac aaaaaaaaaa gaaaaaacat ttcctttaaa   2700

aattcccctt aaatgtaggt ttataaaatg tcagaaatgc cttgtaccca aaacaagtgc   2760

ttaaaaaaaa aaaaaaaaaa aacttgtgct aacaactctt acaattcaga tatatatttt   2820

tataacatct aagactgcaa gagttcttat attcagtagc tctctggttt aagacgacct   2880

ccatctcctt cgcttacaaa acgctttctg cccct                              2915


<210>  7356
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7356

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7357
<211>  2056
<212>  DNA
<213>  Homo sapiens

<400>  7357
acttccgaat tgggtcatgg cggaagggtg ttaatagcct ggccgcccgt gccccaggga     60

atgcttattt ttgaccttag ttgcaaagtg agtttcttct gtatgcttga gtcaagaact    120

ctaagtcatc ttggtaatac cgggttggat gcttaaagct gcagcaaaaa gaccagaact    180

ttcaggaaaa aacactatat ccaacaactc agatatggca gaagtgaagt caatgttccg    240

ggaagttctt ccaaagcaag ggccactgtt tgtggaagat ataatgacaa tggtgctgtg    300

taaacccaaa cttttaccct taaaatctct gactctggaa aaactagaga aaatgcatca    360

agcagcacag aatacaattc gccaacaaga aatggcagaa aaggatcaac ggcaaataac    420

ccactgaatg ataactgagc actttaggga acaacctgcc ttatctacta tttaacaata    480

actagaaaat atgcttctgt gtgctgaaag tagtatgtgt tatcaataaa attgatagta    540

ttcatagaaa tacaaaaata tccaagattg atgaaatttg tattgtgaat gtaaacactc    600

tggtttgtat tgaacataaa cagttaaact atgaaccaag ttttatgggg tttaagtcat    660

gtttttagaa ttgcaaatta aattatttgt tcaccattcc tattgctatc ttttatagat    720

aacattcttg ggatctttta tagcattctt gggcacaagg gattaaatac aacttttata    780

tacagaggat ctttacatgt ttattaaatc tgaatttgaa gatacattcc aatcttgcat    840

aaagtgtttg ttgggctttt acattacgta attaaaaaac aaaatttttt aaccaatttt    900

atgtgccatg tcacgtttaa tgctatcttg tgtgaccaga tcccaccagt aatgacaaaa    960

ctgtcttaaa cctcattttt tttttttttt gagacaagag tttcactctt gttgcccaaa   1020

cgagagcaat ggcaccatct cgactcactg caacctctgc ctcccaggtt caagcaattc   1080

tcctgcctca gcctcccaag tagctgggat tacacgcatg cgccaccatg cctggctact   1140

tttgtatttt taatagagac agggtttctt catgttggtc aagctggtca tgaactccca   1200

acctcaagtg atccgcccac ctcggcctcc caaagtgctg ggattacagg catgagccac   1260

cgtgcccagc ccttaaatct catttttaag aaaccctcac ctattctgta gtcagctaag   1320

cttttaatta cattaatttt aagcacttga gaataaaatg actgcattta tcatccaagt   1380

gtcaaacaat taaaaaccta aaaatggtaa ctatatataa gctgaggtaa tatgggcttg   1440

ataaagccca tgaggtaaat atgaacacta aacttggttt taattctaac agactatatc   1500

taaacctgta agcagtatac tcctaacagt accctcataa attctgaata taattcttgt   1560

ttgctgcagt caatatttgg cagtttaaat tagcacagac gttgaggcct tgctgagtta   1620

ttaggctatg taaaagaggt taaaaatatg atcattcttt attgttaatt ggtaatattt   1680

tctcatacat taggtaaatg tcaagctttg ggtctctgga gtataacttt ttgtaacatt   1740

agccattatt tggtaacaga atttaaggat gatggaatga tggaaggtat tacatatttc   1800

taaaacttaa ttaagctcta ggtcagataa caatggagta aagtgatacc tgcatttttt   1860

tccccagtgt aatcttaatt tactattgta tttttcactt aaaattttgt agggaaaaaa   1920

agttttcaag ggaacactaa gattaaattg actaggttca aatatgcttc cttatgagat   1980

tcaaaattta ctgtgtgaaa ttaaagttta agagacctaa aaaaatgtac tcccaataaa   2040

gaatcaatac tgcttc                                                   2056


<210>  7358
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7358

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7359
<211>  3036
<212>  DNA
<213>  Homo sapiens

<400>  7359
ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc     60

ttttcttctg tatgcttgag tcaagaactc taagtcatct tggtaatacc gggttggatg    120

cttaaagctg cagcaaaaag accagaactt tcaggaaaaa acactatatc caacaactca    180

gatatggcag aagtgaagtc aatgttccgg gaagttcttc caaagcaagg tatgtacatc    240

acaaatattg aggtcattga ttattacagg actaaagaag tcataggcag tgtcacatag    300

caggcttaat agctaaacat ctgcagctat tgtgttccgt attatctcat ttactgtctt    360

ttactatatg ctttttcatg acatccagta aaaggataac aaatgaaaca ttgtttctta    420

tacctaaaat tgcctattaa ttagctaatt cctaaaattc ctaattacaa tatgaatttt    480

ttttaagaga caggttgtca ctctgccacc caggcttggg tacagctggc acaaccgtag    540

ctcaccgcag ccttgaacta ctgggctcct gccctagcct actgatttgc tagtactaca    600

ggcatgtgct accatgcctg gctaatttgt tcttattttt gtagagaagg gatctcaatg    660

tgttgcctag gctggtctca aacccctggg ctcaaacaaa caatccaacc cctttggcat    720

cccaaagtgc tgggataaca ggtaagagct accatgccct actcaatatg aaacttcagt    780

gaaagaaata atggaattta ctatgttaaa taaggtctga aagtggagaa agagaaacct    840

gaagcaacag taagaaaagc cgaaggttta aaccttcagt catttgaata tttacgttaa    900

atatcatatt ttgctatatt tttttgcact atgtatatat atattctgcc aaatcttatt    960

ttaagattaa acttctgaca caaaaagttg tgtcttatgg tagcatagat tcttgggtag   1020

aacgctcaaa acttgtcttc ctcagaagca ccctactagt aagaaatgcg cttatagaat   1080

gacaatgatc tttctggttc cagagcaaaa ctcaatttag gtacaagagt ttttcagtga   1140

caagagatta attttttaga ccttcattct agctgcaaat ccaactacaa acaactgggt   1200

tatctttctt gaattaattc ttatttcttg ttaaacttag ggccactgtt tgtggaagat   1260

ataatgacaa tggtgctgtg taaacccaaa cttttaccct taaaatctct gactctggaa   1320

aaactagaga aaatgcatca agcagcacag aatacaattc gccaacaaga aatggcagaa   1380

aaggatcaac ggcaaataac ccactgaatg ataactgagc actttaggga acaacctgcc   1440

ttatctacta tttaacaata actagaaaat atgcttctgt gtgctgaaag tagtatgtgt   1500

tatcaataaa attgatagta ttcatagaaa tacaaaaata tccaagattg atgaaatttg   1560

tattgtgaat gtaaacactc tggtttgtat tgaacataaa cagttaaact atgaaccaag   1620

ttttatgggg tttaagtcat gtttttagaa ttgcaaatta aattatttgt tcaccattcc   1680

tattgctatc ttttatagat aacattcttg ggatctttta tagcattctt gggcacaagg   1740

gattaaatac aacttttata tacagaggat ctttacatgt ttattaaatc tgaatttgaa   1800

gatacattcc aatcttgcat aaagtgtttg ttgggctttt acattacgta attaaaaaac   1860

aaaatttttt aaccaatttt atgtgccatg tcacgtttaa tgctatcttg tgtgaccaga   1920

tcccaccagt aatgacaaaa ctgtcttaaa cctcattttt tttttttttt gagacaagag   1980

tttcactctt gttgcccaaa cgagagcaat ggcaccatct cgactcactg caacctctgc   2040

ctcccaggtt caagcaattc tcctgcctca gcctcccaag tagctgggat tacacgcatg   2100

cgccaccatg cctggctact tttgtatttt taatagagac agggtttctt catgttggtc   2160

aagctggtca tgaactccca acctcaagtg atccgcccac ctcggcctcc caaagtgctg   2220

ggattacagg catgagccac cgtgcccagc ccttaaatct catttttaag aaaccctcac   2280

ctattctgta gtcagctaag cttttaatta cattaatttt aagcacttga gaataaaatg   2340

actgcattta tcatccaagt gtcaaacaat taaaaaccta aaaatggtaa ctatatataa   2400

gctgaggtaa tatgggcttg ataaagccca tgaggtaaat atgaacacta aacttggttt   2460

taattctaac agactatatc taaacctgta agcagtatac tcctaacagt accctcataa   2520

attctgaata taattcttgt ttgctgcagt caatatttgg cagtttaaat tagcacagac   2580

gttgaggcct tgctgagtta ttaggctatg taaaagaggt taaaaatatg atcattcttt   2640

attgttaatt ggtaatattt tctcatacat taggtaaatg tcaagctttg ggtctctgga   2700

gtataacttt ttgtaacatt agccattatt tggtaacaga atttaaggat gatggaatga   2760

tggaaggtat tacatatttc taaaacttaa ttaagctcta ggtcagataa caatggagta   2820

aagtgatacc tgcatttttt tccccagtgt aatcttaatt tactattgta tttttcactt   2880

aaaattttgt agggaaaaaa agttttcaag ggaacactaa gattaaattg actaggttca   2940

aatatgcttc cttatgagat tcaaaattta ctgtgtgaaa ttaaagttta agagacctaa   3000

aaaaatgtac tcccaataaa gaatcaatac tgcttc                             3036


<210>  7360
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  7360

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Met Tyr Ile Thr Asn Ile Glu Val Ile Asp 
        35                  40                  45


Tyr Tyr Arg Thr Lys Glu Val Ile Gly Ser Val Thr 
    50                  55                  60


<210>  7361
<211>  2123
<212>  DNA
<213>  Homo sapiens

<400>  7361
tccttcgcca gtctcaccgt tacccggggc aacagctgag ccgtctggga agggatgcat     60

cttttcttct gtatgcttga gtcaagaact ctaagtcatc ttggtaatac cgggttggat    120

gcttaaagct gcagcaaaaa gaccagaact ttcaggaaaa aacactatat ccaacaactc    180

agatatggca gaagtgaagt caatgttccg ggaagttctt ccaaagcaag agaagggatc    240

tcaatgtgtt gcctaggctg gtctcaaacc cctgggctca aacaaacaat ccaacccctt    300

tggcatccca aagtgctggg ataacagggc cactgtttgt ggaagatata atgacaatgg    360

tgctgtgtaa acccaaactt ttacccttaa aatctctgac tctggaaaaa ctagagaaaa    420

tgcatcaagc agcacagaat acaattcgcc aacaagaaat ggcagaaaag gatcaacggc    480

aaataaccca ctgaatgata actgagcact ttagggaaca acctgcctta tctactattt    540

aacaataact agaaaatatg cttctgtgtg ctgaaagtag tatgtgttat caataaaatt    600

gatagtattc atagaaatac aaaaatatcc aagattgatg aaatttgtat tgtgaatgta    660

aacactctgg tttgtattga acataaacag ttaaactatg aaccaagttt tatggggttt    720

aagtcatgtt tttagaattg caaattaaat tatttgttca ccattcctat tgctatcttt    780

tatagataac attcttggga tcttttatag cattcttggg cacaagggat taaatacaac    840

ttttatatac agaggatctt tacatgttta ttaaatctga atttgaagat acattccaat    900

cttgcataaa gtgtttgttg ggcttttaca ttacgtaatt aaaaaacaaa attttttaac    960

caattttatg tgccatgtca cgtttaatgc tatcttgtgt gaccagatcc caccagtaat   1020

gacaaaactg tcttaaacct catttttttt tttttttgag acaagagttt cactcttgtt   1080

gcccaaacga gagcaatggc accatctcga ctcactgcaa cctctgcctc ccaggttcaa   1140

gcaattctcc tgcctcagcc tcccaagtag ctgggattac acgcatgcgc caccatgcct   1200

ggctactttt gtatttttaa tagagacagg gtttcttcat gttggtcaag ctggtcatga   1260

actcccaacc tcaagtgatc cgcccacctc ggcctcccaa agtgctggga ttacaggcat   1320

gagccaccgt gcccagccct taaatctcat ttttaagaaa ccctcaccta ttctgtagtc   1380

agctaagctt ttaattacat taattttaag cacttgagaa taaaatgact gcatttatca   1440

tccaagtgtc aaacaattaa aaacctaaaa atggtaacta tatataagct gaggtaatat   1500

gggcttgata aagcccatga ggtaaatatg aacactaaac ttggttttaa ttctaacaga   1560

ctatatctaa acctgtaagc agtatactcc taacagtacc ctcataaatt ctgaatataa   1620

ttcttgtttg ctgcagtcaa tatttggcag tttaaattag cacagacgtt gaggccttgc   1680

tgagttatta ggctatgtaa aagaggttaa aaatatgatc attctttatt gttaattggt   1740

aatattttct catacattag gtaaatgtca agctttgggt ctctggagta taactttttg   1800

taacattagc cattatttgg taacagaatt taaggatgat ggaatgatgg aaggtattac   1860

atatttctaa aacttaatta agctctaggt cagataacaa tggagtaaag tgatacctgc   1920

atttttttcc ccagtgtaat cttaatttac tattgtattt ttcacttaaa attttgtagg   1980

gaaaaaaagt tttcaaggga acactaagat taaattgact aggttcaaat atgcttcctt   2040

atgagattca aaatttactg tgtgaaatta aagtttaaga gacctaaaaa aatgtactcc   2100

caataaagaa tcaatactgc ttc                                           2123


<210>  7362
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  7362

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Glu Lys Gly Ser Gln Cys Val Ala 
        35                  40                  45


<210>  7363
<211>  1962
<212>  DNA
<213>  Homo sapiens

<400>  7363
gtagattttt ttccttcgcc agtctcaccg ttacccgggg caacagctga gccgtctggg     60

aagggatgca tcttttcttc tgtatgcttg agtcaagaac tctaagtcat cttggtaata    120

ccgggttgga tgcttaaagc tgcagcaaaa agaccagaac tttcagggcc actgtttgtg    180

gaagatataa tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact    240

ctggaaaaac tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg    300

gcagaaaagg atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa    360

cctgccttat ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt    420

atgtgttatc aataaaattg atagtattca tagaaataca aaaatatcca agattgatga    480

aatttgtatt gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga    540

accaagtttt atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac    600

cattcctatt gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc    660

acaagggatt aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa    720

tttgaagata cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta    780

aaaaacaaaa ttttttaacc aattttatgt gccatgtcac gtttaatgct atcttgtgtg    840

accagatccc accagtaatg acaaaactgt cttaaacctc attttttttt ttttttgaga    900

caagagtttc actcttgttg cccaaacgag agcaatggca ccatctcgac tcactgcaac    960

ctctgcctcc caggttcaag caattctcct gcctcagcct cccaagtagc tgggattaca   1020

cgcatgcgcc accatgcctg gctacttttg tatttttaat agagacaggg tttcttcatg   1080

ttggtcaagc tggtcatgaa ctcccaacct caagtgatcc gcccacctcg gcctcccaaa   1140

gtgctgggat tacaggcatg agccaccgtg cccagccctt aaatctcatt tttaagaaac   1200

cctcacctat tctgtagtca gctaagcttt taattacatt aattttaagc acttgagaat   1260

aaaatgactg catttatcat ccaagtgtca aacaattaaa aacctaaaaa tggtaactat   1320

atataagctg aggtaatatg ggcttgataa agcccatgag gtaaatatga acactaaact   1380

tggttttaat tctaacagac tatatctaaa cctgtaagca gtatactcct aacagtaccc   1440

tcataaattc tgaatataat tcttgtttgc tgcagtcaat atttggcagt ttaaattagc   1500

acagacgttg aggccttgct gagttattag gctatgtaaa agaggttaaa aatatgatca   1560

ttctttattg ttaattggta atattttctc atacattagg taaatgtcaa gctttgggtc   1620

tctggagtat aactttttgt aacattagcc attatttggt aacagaattt aaggatgatg   1680

gaatgatgga aggtattaca tatttctaaa acttaattaa gctctaggtc agataacaat   1740

ggagtaaagt gatacctgca tttttttccc cagtgtaatc ttaatttact attgtatttt   1800

tcacttaaaa ttttgtaggg aaaaaaagtt ttcaagggaa cactaagatt aaattgacta   1860

ggttcaaata tgcttcctta tgagattcaa aatttactgt gtgaaattaa agtttaagag   1920

acctaaaaaa atgtactccc aataaagaat caatactgct tc                      1962


<210>  7364
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7364

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Pro Leu Phe 
1               5                   10                  15


Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys Leu Leu Pro 
            20                  25                  30


Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His Gln Ala Ala 
        35                  40                  45


Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp Gln Arg Gln 
    50                  55                  60


Ile Thr His 
65


<210>  7365
<211>  1952
<212>  DNA
<213>  Homo sapiens

<400>  7365
agggtgacgt agattttttt ccttcgccag tctcaccgtt acccggggca acagctgagc     60

cgtctgggaa gggatgcatc tgaaaaaaca ctatatccaa caactcagat atggcagaag    120

tgaagtcaat gttccgggaa gttcttccaa agcaagggcc actgtttgtg gaagatataa    180

tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact ctggaaaaac    240

tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg gcagaaaagg    300

atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa cctgccttat    360

ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt atgtgttatc    420

aataaaattg atagtattca tagaaataca aaaatatcca agattgatga aatttgtatt    480

gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga accaagtttt    540

atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac cattcctatt    600

gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc acaagggatt    660

aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa tttgaagata    720

cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta aaaaacaaaa    780

ttttttaacc aattttatgt gccatgtcac gtttaatgct atcttgtgtg accagatccc    840

accagtaatg acaaaactgt cttaaacctc attttttttt ttttttgaga caagagtttc    900

actcttgttg cccaaacgag agcaatggca ccatctcgac tcactgcaac ctctgcctcc    960

caggttcaag caattctcct gcctcagcct cccaagtagc tgggattaca cgcatgcgcc   1020

accatgcctg gctacttttg tatttttaat agagacaggg tttcttcatg ttggtcaagc   1080

tggtcatgaa ctcccaacct caagtgatcc gcccacctcg gcctcccaaa gtgctgggat   1140

tacaggcatg agccaccgtg cccagccctt aaatctcatt tttaagaaac cctcacctat   1200

tctgtagtca gctaagcttt taattacatt aattttaagc acttgagaat aaaatgactg   1260

catttatcat ccaagtgtca aacaattaaa aacctaaaaa tggtaactat atataagctg   1320

aggtaatatg ggcttgataa agcccatgag gtaaatatga acactaaact tggttttaat   1380

tctaacagac tatatctaaa cctgtaagca gtatactcct aacagtaccc tcataaattc   1440

tgaatataat tcttgtttgc tgcagtcaat atttggcagt ttaaattagc acagacgttg   1500

aggccttgct gagttattag gctatgtaaa agaggttaaa aatatgatca ttctttattg   1560

ttaattggta atattttctc atacattagg taaatgtcaa gctttgggtc tctggagtat   1620

aactttttgt aacattagcc attatttggt aacagaattt aaggatgatg gaatgatgga   1680

aggtattaca tatttctaaa acttaattaa gctctaggtc agataacaat ggagtaaagt   1740

gatacctgca tttttttccc cagtgtaatc ttaatttact attgtatttt tcacttaaaa   1800

ttttgtaggg aaaaaaagtt ttcaagggaa cactaagatt aaattgacta ggttcaaata   1860

tgcttcctta tgagattcaa aatttactgt gtgaaattaa agtttaagag acctaaaaaa   1920

atgtactccc aataaagaat caatactgct tc                                 1952


<210>  7366
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7366

Met Ala Glu Val Lys Ser Met Phe Arg Glu Val Leu Pro Lys Gln Gly 
1               5                   10                  15


Pro Leu Phe Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys 
            20                  25                  30


Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His 
        35                  40                  45


Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp 
    50                  55                  60


Gln Arg Gln Ile Thr His 
65                  70


<210>  7367
<211>  2210
<212>  DNA
<213>  Homo sapiens

<400>  7367
ctgtttccag ggtgacgtag atttttttcc ttcgccagtc tcaccgttac ccggggcaac     60

agctgagccg tctgggaagg gatgcatctt ttcttctgta tgcttgagtc aagaactcta    120

agtcatcttg gtaataccgg gttggatgct taaagctgca gcaaaaagac cagaactttc    180

agggcttctc aaatttaata actatggaat cttatcagaa agtccattaa catctcaaag    240

aacaacgtgg ttattgtatc aatcaccatc ctttatacca ggatttgcat atccttcaag    300

atgcctgaag acaatcggag gggtatacaa gcaagcgagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaaccaa ttttatgtgc catgtcacgt ttaatgctat   1080

cttgtgtgac cagatcccac cagtaatgac aaaactgtct taaacctcat tttttttttt   1140

ttttgagaca agagtttcac tcttgttgcc caaacgagag caatggcacc atctcgactc   1200

actgcaacct ctgcctccca ggttcaagca attctcctgc ctcagcctcc caagtagctg   1260

ggattacacg catgcgccac catgcctggc tacttttgta tttttaatag agacagggtt   1320

tcttcatgtt ggtcaagctg gtcatgaact cccaacctca agtgatccgc ccacctcggc   1380

ctcccaaagt gctgggatta caggcatgag ccaccgtgcc cagcccttaa atctcatttt   1440

taagaaaccc tcacctattc tgtagtcagc taagctttta attacattaa ttttaagcac   1500

ttgagaataa aatgactgca tttatcatcc aagtgtcaaa caattaaaaa cctaaaaatg   1560

gtaactatat ataagctgag gtaatatggg cttgataaag cccatgaggt aaatatgaac   1620

actaaacttg gttttaattc taacagacta tatctaaacc tgtaagcagt atactcctaa   1680

cagtaccctc ataaattctg aatataattc ttgtttgctg cagtcaatat ttggcagttt   1740

aaattagcac agacgttgag gccttgctga gttattaggc tatgtaaaag aggttaaaaa   1800

tatgatcatt ctttattgtt aattggtaat attttctcat acattaggta aatgtcaagc   1860

tttgggtctc tggagtataa ctttttgtaa cattagccat tatttggtaa cagaatttaa   1920

ggatgatgga atgatggaag gtattacata tttctaaaac ttaattaagc tctaggtcag   1980

ataacaatgg agtaaagtga tacctgcatt tttttcccca gtgtaatctt aatttactat   2040

tgtatttttc acttaaaatt ttgtagggaa aaaaagtttt caagggaaca ctaagattaa   2100

attgactagg ttcaaatatg cttccttatg agattcaaaa tttactgtgt gaaattaaag   2160

tttaagagac ctaaaaaaat gtactcccaa taaagaatca atactgcttc              2210


<210>  7368
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  7368

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Leu Leu Lys 
1               5                   10                  15


Phe Asn Asn Tyr Gly Ile Leu Ser Glu Ser Pro Leu Thr Ser Gln Arg 
            20                  25                  30


Thr Thr Trp Leu Leu Tyr Gln Ser Pro Ser Phe Ile Pro Gly Phe Ala 
        35                  40                  45


Tyr Pro Ser Arg Cys Leu Lys Thr Ile Gly Gly Val Tyr Lys Gln Ala 
    50                  55                  60


Arg Lys Lys His Tyr Ile Gln Gln Leu Arg Tyr Gly Arg Ser Glu Val 
65                  70                  75                  80


Asn Val Pro Gly Ser Ser Ser Lys Ala Arg Ala Thr Val Cys Gly Arg 
                85                  90                  95


Tyr Asn Asp Asn Gly Ala Val 
            100


<210>  7369
<211>  2210
<212>  DNA
<213>  Homo sapiens

<400>  7369
agttcctcta cgccgtctcc cgcccactgg gcgcctctgg ctagccgggc tacagagtaa     60

gcctccagca gggtagagtg acaactcccc gatcggaagt tactgttgaa gctaaggcgg    120

ccataactga taatggcaaa aggagattcc tggcttcctg tttccagggt gacgtagatt    180

tttttccttc gccagtctca ccgttacccg gggcaacagc tgagccgtct gggaagggat    240

gcatcttttc ttctgtatgc ttgagtcaag aactctaagt catcttggta ataccgggtt    300

ggatgcttaa agctgcagca aaaagaccag aactttcagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaaccaa ttttatgtgc catgtcacgt ttaatgctat   1080

cttgtgtgac cagatcccac cagtaatgac aaaactgtct taaacctcat tttttttttt   1140

ttttgagaca agagtttcac tcttgttgcc caaacgagag caatggcacc atctcgactc   1200

actgcaacct ctgcctccca ggttcaagca attctcctgc ctcagcctcc caagtagctg   1260

ggattacacg catgcgccac catgcctggc tacttttgta tttttaatag agacagggtt   1320

tcttcatgtt ggtcaagctg gtcatgaact cccaacctca agtgatccgc ccacctcggc   1380

ctcccaaagt gctgggatta caggcatgag ccaccgtgcc cagcccttaa atctcatttt   1440

taagaaaccc tcacctattc tgtagtcagc taagctttta attacattaa ttttaagcac   1500

ttgagaataa aatgactgca tttatcatcc aagtgtcaaa caattaaaaa cctaaaaatg   1560

gtaactatat ataagctgag gtaatatggg cttgataaag cccatgaggt aaatatgaac   1620

actaaacttg gttttaattc taacagacta tatctaaacc tgtaagcagt atactcctaa   1680

cagtaccctc ataaattctg aatataattc ttgtttgctg cagtcaatat ttggcagttt   1740

aaattagcac agacgttgag gccttgctga gttattaggc tatgtaaaag aggttaaaaa   1800

tatgatcatt ctttattgtt aattggtaat attttctcat acattaggta aatgtcaagc   1860

tttgggtctc tggagtataa ctttttgtaa cattagccat tatttggtaa cagaatttaa   1920

ggatgatgga atgatggaag gtattacata tttctaaaac ttaattaagc tctaggtcag   1980

ataacaatgg agtaaagtga tacctgcatt tttttcccca gtgtaatctt aatttactat   2040

tgtatttttc acttaaaatt ttgtagggaa aaaaagtttt caagggaaca ctaagattaa   2100

attgactagg ttcaaatatg cttccttatg agattcaaaa tttactgtgt gaaattaaag   2160

tttaagagac ctaaaaaaat gtactcccaa taaagaatca atactgcttc              2210


<210>  7370
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7370

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7371
<211>  894
<212>  DNA
<213>  Homo sapiens

<400>  7371
acttccgaat tgggtcatgg cggaagggtg ttaatagcct ggccgcccgt gccccaggga     60

atgcttattt ttgaccttag ttgcaaagtg agtttcttct gtatgcttga gtcaagaact    120

ctaagtcatc ttggtaatac cgggttggat gcttaaagct gcagcaaaaa gaccagaact    180

ttcaggaaaa aacactatat ccaacaactc agatatggca gaagtgaagt caatgttccg    240

ggaagttctt ccaaagcaag ggccactgtt tgtggaagat ataatgacaa tggtgctgtg    300

taaacccaaa cttttaccct taaaatctct gactctggaa aaactagaga aaatgcatca    360

agcagcacag aatacaattc gccaacaaga aatggcagaa aaggatcaac ggcaaataac    420

ccactgaatg ataactgagc actttaggga acaacctgcc ttatctacta tttaacaata    480

actagaaaat atgcttctgt gtgctgaaag tagtatgtgt tatcaataaa attgatagta    540

ttcatagaaa tacaaaaata tccaagattg atgaaatttg tattgtgaat gtaaacactc    600

tggtttgtat tgaacataaa cagttaaact atgaaccaag ttttatgggg tttaagtcat    660

gtttttagaa ttgcaaatta aattatttgt tcaccattcc tattgctatc ttttatagat    720

aacattcttg ggatctttta tagcattctt gggcacaagg gattaaatac aacttttata    780

tacagaggat ctttacatgt ttattaaatc tgaatttgaa gatacattcc aatcttgcat    840

aaagtgtttg ttgggctttt acattacgta attaaaaaac aaaatttttt aacc          894


<210>  7372
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7372

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7373
<211>  1874
<212>  DNA
<213>  Homo sapiens

<400>  7373
ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc     60

ttttcttctg tatgcttgag tcaagaactc taagtcatct tggtaatacc gggttggatg    120

cttaaagctg cagcaaaaag accagaactt tcaggaaaaa acactatatc caacaactca    180

gatatggcag aagtgaagtc aatgttccgg gaagttcttc caaagcaagg tatgtacatc    240

acaaatattg aggtcattga ttattacagg actaaagaag tcataggcag tgtcacatag    300

caggcttaat agctaaacat ctgcagctat tgtgttccgt attatctcat ttactgtctt    360

ttactatatg ctttttcatg acatccagta aaaggataac aaatgaaaca ttgtttctta    420

tacctaaaat tgcctattaa ttagctaatt cctaaaattc ctaattacaa tatgaatttt    480

ttttaagaga caggttgtca ctctgccacc caggcttggg tacagctggc acaaccgtag    540

ctcaccgcag ccttgaacta ctgggctcct gccctagcct actgatttgc tagtactaca    600

ggcatgtgct accatgcctg gctaatttgt tcttattttt gtagagaagg gatctcaatg    660

tgttgcctag gctggtctca aacccctggg ctcaaacaaa caatccaacc cctttggcat    720

cccaaagtgc tgggataaca ggtaagagct accatgccct actcaatatg aaacttcagt    780

gaaagaaata atggaattta ctatgttaaa taaggtctga aagtggagaa agagaaacct    840

gaagcaacag taagaaaagc cgaaggttta aaccttcagt catttgaata tttacgttaa    900

atatcatatt ttgctatatt tttttgcact atgtatatat atattctgcc aaatcttatt    960

ttaagattaa acttctgaca caaaaagttg tgtcttatgg tagcatagat tcttgggtag   1020

aacgctcaaa acttgtcttc ctcagaagca ccctactagt aagaaatgcg cttatagaat   1080

gacaatgatc tttctggttc cagagcaaaa ctcaatttag gtacaagagt ttttcagtga   1140

caagagatta attttttaga ccttcattct agctgcaaat ccaactacaa acaactgggt   1200

tatctttctt gaattaattc ttatttcttg ttaaacttag ggccactgtt tgtggaagat   1260

ataatgacaa tggtgctgtg taaacccaaa cttttaccct taaaatctct gactctggaa   1320

aaactagaga aaatgcatca agcagcacag aatacaattc gccaacaaga aatggcagaa   1380

aaggatcaac ggcaaataac ccactgaatg ataactgagc actttaggga acaacctgcc   1440

ttatctacta tttaacaata actagaaaat atgcttctgt gtgctgaaag tagtatgtgt   1500

tatcaataaa attgatagta ttcatagaaa tacaaaaata tccaagattg atgaaatttg   1560

tattgtgaat gtaaacactc tggtttgtat tgaacataaa cagttaaact atgaaccaag   1620

ttttatgggg tttaagtcat gtttttagaa ttgcaaatta aattatttgt tcaccattcc   1680

tattgctatc ttttatagat aacattcttg ggatctttta tagcattctt gggcacaagg   1740

gattaaatac aacttttata tacagaggat ctttacatgt ttattaaatc tgaatttgaa   1800

gatacattcc aatcttgcat aaagtgtttg ttgggctttt acattacgta attaaaaaac   1860

aaaatttttt aacc                                                     1874


<210>  7374
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  7374

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Met Tyr Ile Thr Asn Ile Glu Val Ile Asp 
        35                  40                  45


Tyr Tyr Arg Thr Lys Glu Val Ile Gly Ser Val Thr 
    50                  55                  60


<210>  7375
<211>  961
<212>  DNA
<213>  Homo sapiens

<400>  7375
tccttcgcca gtctcaccgt tacccggggc aacagctgag ccgtctggga agggatgcat     60

cttttcttct gtatgcttga gtcaagaact ctaagtcatc ttggtaatac cgggttggat    120

gcttaaagct gcagcaaaaa gaccagaact ttcaggaaaa aacactatat ccaacaactc    180

agatatggca gaagtgaagt caatgttccg ggaagttctt ccaaagcaag agaagggatc    240

tcaatgtgtt gcctaggctg gtctcaaacc cctgggctca aacaaacaat ccaacccctt    300

tggcatccca aagtgctggg ataacagggc cactgtttgt ggaagatata atgacaatgg    360

tgctgtgtaa acccaaactt ttacccttaa aatctctgac tctggaaaaa ctagagaaaa    420

tgcatcaagc agcacagaat acaattcgcc aacaagaaat ggcagaaaag gatcaacggc    480

aaataaccca ctgaatgata actgagcact ttagggaaca acctgcctta tctactattt    540

aacaataact agaaaatatg cttctgtgtg ctgaaagtag tatgtgttat caataaaatt    600

gatagtattc atagaaatac aaaaatatcc aagattgatg aaatttgtat tgtgaatgta    660

aacactctgg tttgtattga acataaacag ttaaactatg aaccaagttt tatggggttt    720

aagtcatgtt tttagaattg caaattaaat tatttgttca ccattcctat tgctatcttt    780

tatagataac attcttggga tcttttatag cattcttggg cacaagggat taaatacaac    840

ttttatatac agaggatctt tacatgttta ttaaatctga atttgaagat acattccaat    900

cttgcataaa gtgtttgttg ggcttttaca ttacgtaatt aaaaaacaaa attttttaac    960

c                                                                    961


<210>  7376
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  7376

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Glu Lys Gly Ser Gln Cys Val Ala 
        35                  40                  45


<210>  7377
<211>  800
<212>  DNA
<213>  Homo sapiens

<400>  7377
gtagattttt ttccttcgcc agtctcaccg ttacccgggg caacagctga gccgtctggg     60

aagggatgca tcttttcttc tgtatgcttg agtcaagaac tctaagtcat cttggtaata    120

ccgggttgga tgcttaaagc tgcagcaaaa agaccagaac tttcagggcc actgtttgtg    180

gaagatataa tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact    240

ctggaaaaac tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg    300

gcagaaaagg atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa    360

cctgccttat ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt    420

atgtgttatc aataaaattg atagtattca tagaaataca aaaatatcca agattgatga    480

aatttgtatt gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga    540

accaagtttt atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac    600

cattcctatt gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc    660

acaagggatt aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa    720

tttgaagata cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta    780

aaaaacaaaa ttttttaacc                                                800


<210>  7378
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7378

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Pro Leu Phe 
1               5                   10                  15


Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys Leu Leu Pro 
            20                  25                  30


Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His Gln Ala Ala 
        35                  40                  45


Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp Gln Arg Gln 
    50                  55                  60


Ile Thr His 
65


<210>  7379
<211>  790
<212>  DNA
<213>  Homo sapiens

<400>  7379
agggtgacgt agattttttt ccttcgccag tctcaccgtt acccggggca acagctgagc     60

cgtctgggaa gggatgcatc tgaaaaaaca ctatatccaa caactcagat atggcagaag    120

tgaagtcaat gttccgggaa gttcttccaa agcaagggcc actgtttgtg gaagatataa    180

tgacaatggt gctgtgtaaa cccaaacttt tacccttaaa atctctgact ctggaaaaac    240

tagagaaaat gcatcaagca gcacagaata caattcgcca acaagaaatg gcagaaaagg    300

atcaacggca aataacccac tgaatgataa ctgagcactt tagggaacaa cctgccttat    360

ctactattta acaataacta gaaaatatgc ttctgtgtgc tgaaagtagt atgtgttatc    420

aataaaattg atagtattca tagaaataca aaaatatcca agattgatga aatttgtatt    480

gtgaatgtaa acactctggt ttgtattgaa cataaacagt taaactatga accaagtttt    540

atggggttta agtcatgttt ttagaattgc aaattaaatt atttgttcac cattcctatt    600

gctatctttt atagataaca ttcttgggat cttttatagc attcttgggc acaagggatt    660

aaatacaact tttatataca gaggatcttt acatgtttat taaatctgaa tttgaagata    720

cattccaatc ttgcataaag tgtttgttgg gcttttacat tacgtaatta aaaaacaaaa    780

ttttttaacc                                                           790


<210>  7380
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7380

Met Ala Glu Val Lys Ser Met Phe Arg Glu Val Leu Pro Lys Gln Gly 
1               5                   10                  15


Pro Leu Phe Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys 
            20                  25                  30


Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His 
        35                  40                  45


Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp 
    50                  55                  60


Gln Arg Gln Ile Thr His 
65                  70


<210>  7381
<211>  1048
<212>  DNA
<213>  Homo sapiens

<400>  7381
ctgtttccag ggtgacgtag atttttttcc ttcgccagtc tcaccgttac ccggggcaac     60

agctgagccg tctgggaagg gatgcatctt ttcttctgta tgcttgagtc aagaactcta    120

agtcatcttg gtaataccgg gttggatgct taaagctgca gcaaaaagac cagaactttc    180

agggcttctc aaatttaata actatggaat cttatcagaa agtccattaa catctcaaag    240

aacaacgtgg ttattgtatc aatcaccatc ctttatacca ggatttgcat atccttcaag    300

atgcctgaag acaatcggag gggtatacaa gcaagcgagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaacc                                      1048


<210>  7382
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  7382

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Leu Leu Lys 
1               5                   10                  15


Phe Asn Asn Tyr Gly Ile Leu Ser Glu Ser Pro Leu Thr Ser Gln Arg 
            20                  25                  30


Thr Thr Trp Leu Leu Tyr Gln Ser Pro Ser Phe Ile Pro Gly Phe Ala 
        35                  40                  45


Tyr Pro Ser Arg Cys Leu Lys Thr Ile Gly Gly Val Tyr Lys Gln Ala 
    50                  55                  60


Arg Lys Lys His Tyr Ile Gln Gln Leu Arg Tyr Gly Arg Ser Glu Val 
65                  70                  75                  80


Asn Val Pro Gly Ser Ser Ser Lys Ala Arg Ala Thr Val Cys Gly Arg 
                85                  90                  95


Tyr Asn Asp Asn Gly Ala Val 
            100


<210>  7383
<211>  1048
<212>  DNA
<213>  Homo sapiens

<400>  7383
agttcctcta cgccgtctcc cgcccactgg gcgcctctgg ctagccgggc tacagagtaa     60

gcctccagca gggtagagtg acaactcccc gatcggaagt tactgttgaa gctaaggcgg    120

ccataactga taatggcaaa aggagattcc tggcttcctg tttccagggt gacgtagatt    180

tttttccttc gccagtctca ccgttacccg gggcaacagc tgagccgtct gggaagggat    240

gcatcttttc ttctgtatgc ttgagtcaag aactctaagt catcttggta ataccgggtt    300

ggatgcttaa agctgcagca aaaagaccag aactttcagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatacaaa aatatccaag    720

attgatgaaa tttgtattgt gaatgtaaac actctggttt gtattgaaca taaacagtta    780

aactatgaac caagttttat ggggtttaag tcatgttttt agaattgcaa attaaattat    840

ttgttcacca ttcctattgc tatcttttat agataacatt cttgggatct tttatagcat    900

tcttgggcac aagggattaa atacaacttt tatatacaga ggatctttac atgtttatta    960

aatctgaatt tgaagataca ttccaatctt gcataaagtg tttgttgggc ttttacatta   1020

cgtaattaaa aaacaaaatt ttttaacc                                      1048


<210>  7384
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7384

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7385
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  7385
acttccgaat tgggtcatgg cggaagggtg ttaatagcct ggccgcccgt gccccaggga     60

atgcttattt ttgaccttag ttgcaaagtg agtttcttct gtatgcttga gtcaagaact    120

ctaagtcatc ttggtaatac cgggttggat gcttaaagct gcagcaaaaa gaccagaact    180

ttcaggaaaa aacactatat ccaacaactc agatatggca gaagtgaagt caatgttccg    240

ggaagttctt ccaaagcaag ggccactgtt tgtggaagat ataatgacaa tggtgctgtg    300

taaacccaaa cttttaccct taaaatctct gactctggaa aaactagaga aaatgcatca    360

agcagcacag aatacaattc gccaacaaga aatggcagaa aaggatcaac ggcaaataac    420

ccactgaatg ataactgagc actttaggga acaacctgcc ttatctacta tttaacaata    480

actagaaaat atgcttctgt gtgctgaaag tagtatgtgt tatcaataaa attgatagta    540

ttcatagaaa tac                                                       553


<210>  7386
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7386

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7387
<211>  1533
<212>  DNA
<213>  Homo sapiens

<400>  7387
ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc     60

ttttcttctg tatgcttgag tcaagaactc taagtcatct tggtaatacc gggttggatg    120

cttaaagctg cagcaaaaag accagaactt tcaggaaaaa acactatatc caacaactca    180

gatatggcag aagtgaagtc aatgttccgg gaagttcttc caaagcaagg tatgtacatc    240

acaaatattg aggtcattga ttattacagg actaaagaag tcataggcag tgtcacatag    300

caggcttaat agctaaacat ctgcagctat tgtgttccgt attatctcat ttactgtctt    360

ttactatatg ctttttcatg acatccagta aaaggataac aaatgaaaca ttgtttctta    420

tacctaaaat tgcctattaa ttagctaatt cctaaaattc ctaattacaa tatgaatttt    480

ttttaagaga caggttgtca ctctgccacc caggcttggg tacagctggc acaaccgtag    540

ctcaccgcag ccttgaacta ctgggctcct gccctagcct actgatttgc tagtactaca    600

ggcatgtgct accatgcctg gctaatttgt tcttattttt gtagagaagg gatctcaatg    660

tgttgcctag gctggtctca aacccctggg ctcaaacaaa caatccaacc cctttggcat    720

cccaaagtgc tgggataaca ggtaagagct accatgccct actcaatatg aaacttcagt    780

gaaagaaata atggaattta ctatgttaaa taaggtctga aagtggagaa agagaaacct    840

gaagcaacag taagaaaagc cgaaggttta aaccttcagt catttgaata tttacgttaa    900

atatcatatt ttgctatatt tttttgcact atgtatatat atattctgcc aaatcttatt    960

ttaagattaa acttctgaca caaaaagttg tgtcttatgg tagcatagat tcttgggtag   1020

aacgctcaaa acttgtcttc ctcagaagca ccctactagt aagaaatgcg cttatagaat   1080

gacaatgatc tttctggttc cagagcaaaa ctcaatttag gtacaagagt ttttcagtga   1140

caagagatta attttttaga ccttcattct agctgcaaat ccaactacaa acaactgggt   1200

tatctttctt gaattaattc ttatttcttg ttaaacttag ggccactgtt tgtggaagat   1260

ataatgacaa tggtgctgtg taaacccaaa cttttaccct taaaatctct gactctggaa   1320

aaactagaga aaatgcatca agcagcacag aatacaattc gccaacaaga aatggcagaa   1380

aaggatcaac ggcaaataac ccactgaatg ataactgagc actttaggga acaacctgcc   1440

ttatctacta tttaacaata actagaaaat atgcttctgt gtgctgaaag tagtatgtgt   1500

tatcaataaa attgatagta ttcatagaaa tac                                1533


<210>  7388
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  7388

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Met Tyr Ile Thr Asn Ile Glu Val Ile Asp 
        35                  40                  45


Tyr Tyr Arg Thr Lys Glu Val Ile Gly Ser Val Thr 
    50                  55                  60


<210>  7389
<211>  429
<212>  DNA
<213>  Homo sapiens

<400>  7389
ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc     60

tgaaaaaaca ctatatccaa caactcagat atggcagaag tgaagtcaat gttccgggaa    120

gttcttccaa agcaagggcc actgtttgtg gaagatataa tgacaatggt gctgtgtaaa    180

cccaaacttt tacccttaaa atctctgact ctggaaaaac tagagaaaat gcatcaagca    240

gcacagaata caattcgcca acaagaaatg gcagaaaagg atcaacggca aataacccac    300

tgaatgataa ctgagcactt tagggaacaa cctgccttat ctactattta acaataacta    360

gaaaatatgc ttctgtgtgc tgaaagtagt atgtgttatc aataaaattg atagtattca    420

tagaaatac                                                            429


<210>  7390
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7390

Met Ala Glu Val Lys Ser Met Phe Arg Glu Val Leu Pro Lys Gln Gly 
1               5                   10                  15


Pro Leu Phe Val Glu Asp Ile Met Thr Met Val Leu Cys Lys Pro Lys 
            20                  25                  30


Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu Lys Leu Glu Lys Met His 
        35                  40                  45


Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln Glu Met Ala Glu Lys Asp 
    50                  55                  60


Gln Arg Gln Ile Thr His 
65                  70


<210>  7391
<211>  707
<212>  DNA
<213>  Homo sapiens

<400>  7391
agttcctcta cgccgtctcc cgcccactgg gcgcctctgg ctagccgggc tacagagtaa     60

gcctccagca gggtagagtg acaactcccc gatcggaagt tactgttgaa gctaaggcgg    120

ccataactga taatggcaaa aggagattcc tggcttcctg tttccagggt gacgtagatt    180

tttttccttc gccagtctca ccgttacccg gggcaacagc tgagccgtct gggaagggat    240

gcatcttttc ttctgtatgc ttgagtcaag aactctaagt catcttggta ataccgggtt    300

ggatgcttaa agctgcagca aaaagaccag aactttcagg aaaaaacact atatccaaca    360

actcagatat ggcagaagtg aagtcaatgt tccgggaagt tcttccaaag caagggccac    420

tgtttgtgga agatataatg acaatggtgc tgtgtaaacc caaactttta cccttaaaat    480

ctctgactct ggaaaaacta gagaaaatgc atcaagcagc acagaataca attcgccaac    540

aagaaatggc agaaaaggat caacggcaaa taacccactg aatgataact gagcacttta    600

gggaacaacc tgccttatct actatttaac aataactaga aaatatgctt ctgtgtgctg    660

aaagtagtat gtgttatcaa taaaattgat agtattcata gaaatac                  707


<210>  7392
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7392

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Lys Asn Thr 
1               5                   10                  15


Ile Ser Asn Asn Ser Asp Met Ala Glu Val Lys Ser Met Phe Arg Glu 
            20                  25                  30


Val Leu Pro Lys Gln Gly Pro Leu Phe Val Glu Asp Ile Met Thr Met 
        35                  40                  45


Val Leu Cys Lys Pro Lys Leu Leu Pro Leu Lys Ser Leu Thr Leu Glu 
    50                  55                  60


Lys Leu Glu Lys Met His Gln Ala Ala Gln Asn Thr Ile Arg Gln Gln 
65                  70                  75                  80


Glu Met Ala Glu Lys Asp Gln Arg Gln Ile Thr His 
                85                  90


<210>  7393
<211>  1498
<212>  DNA
<213>  Homo sapiens

<400>  7393
accgttaccc ggggcaacag ctgagccgtc tgggaaggga tgcatctttt cttctgtatg     60

cttgagtcaa gaactctaag tcatcttggt aataccgggt tggatgctta aagctgcagc    120

aaaaagacca gaactttcag ggcttctcaa atttaataac tatggaatct tatcagaaag    180

tccattaaca tctcaaagaa caacgtggtt attgtatcaa tcaccatcct ttataccagg    240

atttgcatat ccttcaagat gcctgaagac aatcggaggg gtatacaagc aagcgaggtt    300

aagaacaatc acttttcaga tcctaaactt ttatatgtag tgtctgctga taatgcattc    360

cctgagaaaa tggacctgtg gataaaccat catgcttcat ctcatttcct gtctcctctt    420

tcaccatttt tctttctttt cttttctttt tttttttttt tcttgagaca agctcttact    480

ctgtcaccta agctagaatg cagtggcgtg atcatatctc actgcaacct aaaactcagg    540

ctcaagcagt accctcacct cagcctcccg agtagctgag actaacaggc acactccatc    600

atgcccgaat aatttttgtt aattttttgt agagatgagg tcttgctttg ttgtctaggc    660

tggtcttgaa ctgggctcaa gcgatcctcc cactttggcc ttccaaagtg ctgggattcc    720

agatgcgagc caccgcacca gtcccccaat tatttttcta aggatgtatg aaggaaaggc    780

atctctctag cctggtagaa tcttactatg acaaaaatgc tccagaaaat aaacatctct    840

taggagctac acacagagac aaggaaacac tggtaactca agaaagacta agggcttcgc    900

taattattaa gtaagtagtg cttctgcaag tcaagagact gttctcagct ttcaacaata    960

ctgaaggaat acctaattga gtagtctgct ggtcatttaa aattatttct tgatgatagg   1020

tcactacgtg attgttagca tataacgtaa gttcaaagat tgaaaaaaat tttcccattt   1080

tcatctcagt gtttacatct acaaaaatga agaatagggc tgggcacagt ggctcacgcc   1140

tgtaatccca gcactttggg aggccaacgg gggcggatca cttgaggtca gaagttcgag   1200

accagcctgg ccaacatggt gaaaccctgt ctctactgaa aatacaaaaa ttagccgggc   1260

atggtggcat gcgcctgtaa tcccagctac tcgggagtct caggcaggag aattgcttga   1320

atccaggtgg cggaggttgc agtgagccga gatcgtgcca ctgcacccca gcctgggcaa   1380

cagagcaaga ctccatctca aaaaaaagga agaagaatag aattgtagca ataagtaaat   1440

ttcagccatg tatatacgtg aactaattga gaaaataaag ctgtcttctt attaacag     1498


<210>  7394
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  7394

Met Leu Lys Ala Ala Ala Lys Arg Pro Glu Leu Ser Gly Leu Leu Lys 
1               5                   10                  15


Phe Asn Asn Tyr Gly Ile Leu Ser Glu Ser Pro Leu Thr Ser Gln Arg 
            20                  25                  30


Thr Thr Trp Leu Leu Tyr Gln Ser Pro Ser Phe Ile Pro Gly Phe Ala 
        35                  40                  45


Tyr Pro Ser Arg Cys Leu Lys Thr Ile Gly Gly Val Tyr Lys Gln Ala 
    50                  55                  60


Arg Leu Arg Thr Ile Thr Phe Gln Ile Leu Asn Phe Tyr Met 
65                  70                  75


<210>  7395
<211>  2224
<212>  DNA
<213>  Homo sapiens

<400>  7395
tactctcgct ccagcctccc cgccccaccc ctctgccgtg ggcccgtcac tcgctagttc     60

ctctacgccg tctcccgccc actgggcgcc tctggctagc cgggctacag agtaagcctc    120

cagcagggta gagtgacaac tccccgatcg gaagttactg ttgaagctaa ggcggccata    180

actgataatg gcaaaaggag attcctggct tcctgtttcc agggtgacgt agattttttt    240

ccttcgccag tctcaccgtt acccggggca acagctgagc cgtctgggaa gggatgcatc    300

tgtaagtaag cccaaagagg taccgtgggt gaccacacat cccatgttag acaagttaat    360

tcatactccg gattacacgt ccagtttcct ggcccttatt ttactgagac gtctggtcac    420

ttacggagat ggacaacagt ttagggctcc gaaattccct ctcctgcccg gaagttgcat    480

ttggcacttc cgaattgggt catggcggaa gggtgttaat agcctggccg cccgtgcccc    540

agggaatgct tatttttgac cttagttgca aagtgaggtg agtccgtgga ccccaaccag    600

tgggccggac ccgggccgga cggtccctgt gggacagagc gctgaaatgg cgagcggggc    660

tcagggccgc ttccgttgga aggcggtttt tttccgggct ggcctggcgg cggcccgccc    720

ccgtgaggct ccctgtgggg tgaggccgct ctacaggccg ccctaaccca gccagaggca    780

gcccggccgg gaggacccca gcggggaatg ggcggggacc tcggggcgga gctcctaact    840

ccggcaaaac ggagctcttg accacgcctc cgcaagttcc tattaagtac tttcactcct    900

tggcctttgg agggaggaga attcgggaac ttcagaaaat cattttccac cttcacctat    960

aaaaggaaaa gatgagcccc taccaccagg gcaggacctc aatctttttc ccctgccacc   1020

tgccttccca ttctgatttt tccccccttt ccgcgtctct cctttgagtc tttgtaagct   1080

ttgactgcgg ttctggtggt gggattcctg caggtctaca gtttcttaaa caacgtgttg   1140

aagatttttg aaaatactgt attgctttta tatggccctt tacaaagtta tcatacatta   1200

tcttgtagtt tcttctgtat gcttgagtca agaactctaa gtcatcttgg taataccggg   1260

ttggatgctt aaagctgcag caaaaagacc agaactttca ggtaaaattg aaaatggtta   1320

atatccagcc agtcaacaat acagatgcaa acctaccttc tcgacttaat ttctgcttcc   1380

ttagtactta cacgccagcc aaaatgaact actcttgttt ctttgctgtt aattactgaa   1440

atctgttgta gcagtcacct tttgtgattc tgtatctgat tctgttaccc gtggagatgt   1500

gtttccagat tcttcccagc aggaagtaat ttcctctgag tttagcattt tttgtacatc   1560

ttttatgaca atcagtatgt tatatatata taatagcgct tatgttttta gcttcactac   1620

catgtctgca cctaaataga atggtttgta tcagattcgt cttcccgtca ttttcaccat   1680

gcacatgata ttattttggt aaatacttac tgaaagtttg aatatatcgg gtgtctcttg   1740

gatgcccaag acacttccag ccaagtttta gagaccttca atttatcaga aattcagctg   1800

agcgcctgct actcaatctt tgttttacgt ttcccctgtg aagtctttct gacatgattt   1860

ttttccccag tgttttatta tgaaagtgtt catatattta aaagctgaaa gaaataattt   1920

aatgaatatt catgtaccca tcatctatat gcagcagtta acattttgcc attttttttc   1980

attcctcccc actttttcat tgtcataaaa agttgcagac acttattgtt aggcaagaca   2040

cccttaagat ttccagcatg aatttcctaa gaattttgaa gttctccagc aaaacacaat   2100

atcattattt cagctgtttt gtaactttta aaatctaggc caagtgctaa ttttcctaat   2160

ttacccagga atatctttta taccttctcc ttcccaatcc tgcaaaaaaa aaaaaaaaaa   2220

aaaa                                                                2224


<210>  7396
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  7396

Met Leu Asp Lys Leu Ile His Thr Pro Asp Tyr Thr Ser Ser Phe Leu 
1               5                   10                  15


Ala Leu Ile Leu Leu Arg Arg Leu Val Thr Tyr Gly Asp Gly Gln Gln 
            20                  25                  30


Phe Arg Ala Pro Lys Phe Pro Leu Leu Pro Gly Ser Cys Ile Trp His 
        35                  40                  45


Phe Arg Ile Gly Ser Trp Arg Lys Gly Val Asn Ser Leu Ala Ala Arg 
    50                  55                  60


Ala Pro Gly Asn Ala Tyr Phe 
65                  70


<210>  7397
<211>  3943
<212>  DNA
<213>  Homo sapiens

<400>  7397
gggggagggg cgggcggggg gcggcggttg ggcagcgtcg cttcttagga ggaggaggaa     60

gaggaggaag gagggcgagc gaggaggatg gcggagtcgg ggctcctgac ggaactctaa    120

tgaatcattg attgaccagc actattttac cagttggaat gaatgatcag aaatgggcat    180

agtgctttta gatccaacat gtaacagatg gatgttactc catgctgatt acttcttcaa    240

gccagtactt ttttgattgt gtaggatctt tgtctcttca tctttgaatt caattactgg    300

aaaataaaag gagttcatgt agtttttgtc caggcttgag tcaccatgag tagtagttta    360

ggaaaagaaa aagactctaa agaaaaagat cccaaagtac catcagccaa ggaaagagaa    420

aaggaggcaa aagcctctgg aggttttggg aaagagagca aagaaaaaga acctaagacc    480

aaagggaaag atgccaaaga tggaaagaag gactccagtg ctgcccaacc aggggtggca    540

ttttcagttg acaatacgat caaacggcca aacccagcac ctgggactag aaaaaaatcc    600

agcaatgcag aggtgattaa agagctcaac aaatgccggg aagagaattc aatgcgtttg    660

gacttatcca agagatctat acacatattg ccatcatcaa tcaaagagtt gactcaatta    720

acagaacttt atttatacag taacaaattg cagtccctcc cagcagaggt gggatgttta    780

gtaaatctca tgacactggc tctaagtgaa aattcactta ccagtttgcc tgactctctt    840

gataacttga agaagctgcg gatgcttgat ttacggcata ataaactgag agaaattcct    900

tcagtggtgt ataggctgga ttctctcacc actctttacc ttcgctttaa tcgtataact    960

actgtggaaa aggacatcaa aaacttgtca aaactcagca tgcttagcat tcgagagaac   1020

aaaattaaac aactacctgc tgaaattggt gaattatgta acctcattac gctggatgta   1080

gctcacaatc aacttgaaca ccttccaaag gagattggaa actgtacaca gataaccaac   1140

cttgacttgc agcacaatga actgctagac ctcccagata ctataggaaa cctgtccagt   1200

ttaagtcgtc ttggtctgag atataacaga ctgtcagcaa tacccagatc attagcaaaa   1260

tgcagtgcac ttgaagaatt aaatttagag aacaataaca tttctacttt accagagagt   1320

cttttatcaa gtcttgtgaa actgaatagt ttgaccttag ctagaaattg cttccagttg   1380

tatccagtgg gtggtccatc tcagttttct accatctatt ccctcaacat ggaacacaat   1440

cgaatcaaca aaattccatt tggaattttc tccagagcaa aagtattaag taagctgaat   1500

atgaaggaca atcagttaac atcacttccc ttggattttg gaacttggac cagtatggta   1560

gaattgaatt tagccactaa tcagctcaca aagatccctg aggatgtgtc tggtctcgtt   1620

tctcttgagg ttcttatctt atcaaacaat cttctaaaga agcttcccca tggtcttgga   1680

aaccttagga agttaagaga gttggatcta gaagagaaca aattggaatc cttgccaaat   1740

gaaattgcat atcttaagga tttacagaaa ttagtcttga caaacaacca gttgaccact   1800

cttcccagag gcattggtca ccttactaat ctcacacatc tgggccttgg agagaaccta   1860

cttactcacc ttcctgaaga aattggtaca ctggagaacc tagaagaact gtatttgaat   1920

gacaacccca acctgcatag ccttcccttt gagctggcac tctgcagcaa gctttcaatc   1980

atgagtattg agaactgtcc actcagtcac cttccacctc agattgttgc tggggggcct   2040

tctttcatca ttcagttctt aaagatgcag ggtccatatc gtgccatggt ctgatataaa   2100

tctgctggtc ccacacactg ttcaaaaata gactgccatt aatgtttctt atctatatct   2160

gtatctattt atgtagatat tggtatatgg cagatttata aaaattgcat tatgtgtttc   2220

tgctaataga ggaatcatag ccatttagaa ttttttttaa attctgtaca aaaggcttat   2280

ataagttttc tttgctgaat ttgatggatg tttttctgtt gtgtaatctg atatgccagt   2340

ttgcttaaaa catttgccaa cacattatga agttattaaa tttaagggac agaggtagta   2400

tagttagata tactttctct taggaaaaat aatgggcaaa aatttttgtt gcaacttttc   2460

atatatattt tccccttacc aattgtttta tccttatagt attgtaggcc ctgaaagtag   2520

aatttttctt taacttattt tgagatttga gatttaaatt ttatgtattg tttacagtca   2580

gagtaaatca ctggatttct tttgtttgtt ttgatttgct ctgttttatt cagtcaaatc   2640

tagagtttga atcctctgct aaagaatttg catccactgg tgtaaacagt gaaaggtatt   2700

tgcttgttga aaaaaaaaac tggcaaagtg aaaagataca gtcaaaaatc tagaatttct   2760

ttaattttgc ttctctgacg agttgtgaag caaaatacct gaagtgagtc tttgggtagg   2820

ggaagggtat tgagaccttt tctagtatga atatttttta agtttggggg aagagaaact   2880

tgcagtgaaa aggagttttt tcattcctga aagttgcaga tccacaaaac taacaggata   2940

attgggcaaa taaattacat ataaacacac acaatctata tatgtatata caatgctata   3000

tagatatgta tttattatat cataaactac agtaggtaac tttaaggatt tcttcctatc   3060

cttgtacaat gacatgaatg tctttctttg aaaactgcaa tgtatgtatg tttcaaggtt   3120

atttaacagt gtactatggt tttatatctt gacttgcctt gtacatcttt caattctgga   3180

atatctgtgt ctaagcacaa tatcttcaca ctgtgctgta ttgctgctga actaaatgca   3240

cttttcccca catatggggc actggcttca aacaattcag ttcagtatca ttacttttaa   3300

tctcatcttt cctttcttgg tagttgttaa tacagttatg gaaaagaggc acattgcata   3360

gaagccattg gggagttcag tggaagttct gtaagatgtg catgtactat ttgatgcgtt   3420

ttctttgctt cactgctttt aatacttagc agtattgttg gtctaagtca atttgattat   3480

tgaggagtct cagagcaagg tgcgttctag atgtcatcct aaaaaacact tcatatataa   3540

ttaatcacta ttttgtataa ttacatattg ctgcttgtgt gttttttttt ttttccattt   3600

agttgggcgt tgtgttttac acaaaaccat ttttgaatta aggctatgat attaagatag   3660

aaatttggac tgttgttctg cttttcctgg cactcaaatt catgactagt tttgaggtca   3720

aacctatgtt cgtaatgaga gattttataa ggatcaacta agaaatggaa ggcaggtgaa   3780

gatataaaac cctagaatgc ttaaatgtgc tgtaaaacta ttgtagatgt cactggattt   3840

taccaagtaa tatcctttct tttttttttc cccccatctg ctgtggcttt tcagttaaaa   3900

ttttgtttat aaaaggaatt tgtttattac agctctacct aga                     3943


<210>  7398
<211>  582
<212>  PRT
<213>  Homo sapiens

<400>  7398

Met Ser Ser Ser Leu Gly Lys Glu Lys Asp Ser Lys Glu Lys Asp Pro 
1               5                   10                  15


Lys Val Pro Ser Ala Lys Glu Arg Glu Lys Glu Ala Lys Ala Ser Gly 
            20                  25                  30


Gly Phe Gly Lys Glu Ser Lys Glu Lys Glu Pro Lys Thr Lys Gly Lys 
        35                  40                  45


Asp Ala Lys Asp Gly Lys Lys Asp Ser Ser Ala Ala Gln Pro Gly Val 
    50                  55                  60


Ala Phe Ser Val Asp Asn Thr Ile Lys Arg Pro Asn Pro Ala Pro Gly 
65                  70                  75                  80


Thr Arg Lys Lys Ser Ser Asn Ala Glu Val Ile Lys Glu Leu Asn Lys 
                85                  90                  95


Cys Arg Glu Glu Asn Ser Met Arg Leu Asp Leu Ser Lys Arg Ser Ile 
            100                 105                 110


His Ile Leu Pro Ser Ser Ile Lys Glu Leu Thr Gln Leu Thr Glu Leu 
        115                 120                 125


Tyr Leu Tyr Ser Asn Lys Leu Gln Ser Leu Pro Ala Glu Val Gly Cys 
    130                 135                 140


Leu Val Asn Leu Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser 
145                 150                 155                 160


Leu Pro Asp Ser Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu 
                165                 170                 175


Arg His Asn Lys Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp 
            180                 185                 190


Ser Leu Thr Thr Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu 
        195                 200                 205


Lys Asp Ile Lys Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu 
    210                 215                 220


Asn Lys Ile Lys Gln Leu Pro Ala Glu Ile Gly Glu Leu Cys Asn Leu 
225                 230                 235                 240


Ile Thr Leu Asp Val Ala His Asn Gln Leu Glu His Leu Pro Lys Glu 
                245                 250                 255


Ile Gly Asn Cys Thr Gln Ile Thr Asn Leu Asp Leu Gln His Asn Glu 
            260                 265                 270


Leu Leu Asp Leu Pro Asp Thr Ile Gly Asn Leu Ser Ser Leu Ser Arg 
        275                 280                 285


Leu Gly Leu Arg Tyr Asn Arg Leu Ser Ala Ile Pro Arg Ser Leu Ala 
    290                 295                 300


Lys Cys Ser Ala Leu Glu Glu Leu Asn Leu Glu Asn Asn Asn Ile Ser 
305                 310                 315                 320


Thr Leu Pro Glu Ser Leu Leu Ser Ser Leu Val Lys Leu Asn Ser Leu 
                325                 330                 335


Thr Leu Ala Arg Asn Cys Phe Gln Leu Tyr Pro Val Gly Gly Pro Ser 
            340                 345                 350


Gln Phe Ser Thr Ile Tyr Ser Leu Asn Met Glu His Asn Arg Ile Asn 
        355                 360                 365


Lys Ile Pro Phe Gly Ile Phe Ser Arg Ala Lys Val Leu Ser Lys Leu 
    370                 375                 380


Asn Met Lys Asp Asn Gln Leu Thr Ser Leu Pro Leu Asp Phe Gly Thr 
385                 390                 395                 400


Trp Thr Ser Met Val Glu Leu Asn Leu Ala Thr Asn Gln Leu Thr Lys 
                405                 410                 415


Ile Pro Glu Asp Val Ser Gly Leu Val Ser Leu Glu Val Leu Ile Leu 
            420                 425                 430


Ser Asn Asn Leu Leu Lys Lys Leu Pro His Gly Leu Gly Asn Leu Arg 
        435                 440                 445


Lys Leu Arg Glu Leu Asp Leu Glu Glu Asn Lys Leu Glu Ser Leu Pro 
    450                 455                 460


Asn Glu Ile Ala Tyr Leu Lys Asp Leu Gln Lys Leu Val Leu Thr Asn 
465                 470                 475                 480


Asn Gln Leu Thr Thr Leu Pro Arg Gly Ile Gly His Leu Thr Asn Leu 
                485                 490                 495


Thr His Leu Gly Leu Gly Glu Asn Leu Leu Thr His Leu Pro Glu Glu 
            500                 505                 510


Ile Gly Thr Leu Glu Asn Leu Glu Glu Leu Tyr Leu Asn Asp Asn Pro 
        515                 520                 525


Asn Leu His Ser Leu Pro Phe Glu Leu Ala Leu Cys Ser Lys Leu Ser 
    530                 535                 540


Ile Met Ser Ile Glu Asn Cys Pro Leu Ser His Leu Pro Pro Gln Ile 
545                 550                 555                 560


Val Ala Gly Gly Pro Ser Phe Ile Ile Gln Phe Leu Lys Met Gln Gly 
                565                 570                 575


Pro Tyr Arg Ala Met Val 
            580


<210>  7399
<211>  3761
<212>  DNA
<213>  Homo sapiens

<400>  7399
ggttgggcag cgtcgcttct taggaggagg aggaagagga ggaaggaggg cgagcgagga     60

ggatggcgga gtcggggctc ctgacggaac tctaatgaat cattgattga ccagcactat    120

tttaccagtt ggaatgaatg atcagaaatg ggcatagtgc ttttagatcc aacatgtaac    180

agatggatgt tactccatgc tgattacttc ttcaagccag tacttttttg attgtgtagg    240

atctttgtct cttcatcttt gaattcaatt actggaaaat aaaaggagtt catgtagttt    300

ttgtccaggc ttgagtcacc atgagtagta gtttaggaaa agaaaaagac tctaaagaaa    360

aagatcccaa agtaccatca gccaaggaaa gagaaaagga ggcaaaagcc tctggaggtt    420

ttgggaaaga gagcaaagaa aaagaaccta agaccaaagg gaaagatgcc aaagatggaa    480

agaaggactc cagtgctgcc caaccagggg tggcattttc agttgacaat acgatcaaac    540

ggccaaaccc agcacctggg actagaaaaa aatccagcaa tcagaggtgg gatgtttagt    600

aaatctcatg acactggctc taagtgaaaa ttcacttacc agtttgcctg actctcttga    660

taacttgaag aagctgcgga tgcttgattt acggcataat aaactgagag aaattccttc    720

agtggtgtat aggctggatt ctctcaccac tctttacctt cgctttaatc gtataactac    780

tgtggaaaag gacatcaaaa acttgtcaaa actcagcatg cttagcattc gagagaacaa    840

aattaaacaa ctacctgctg aaattggtga attatgtaac ctcattacgc tggatgtagc    900

tcacaatcaa cttgaacacc ttccaaagga gattggaaac tgtacacaga taaccaacct    960

tgacttgcag cacaatgaac tgctagacct cccagatact ataggaaacc tgtccagttt   1020

aagtcgtctt ggtctgagat ataacagact gtcagcaata cccagatcat tagcaaaatg   1080

cagtgcactt gaagaattaa atttagagaa caataacatt tctactttac cagagagtct   1140

tttatcaagt cttgtgaaac tgaatagttt gaccttagct agaaattgct tccagttgta   1200

tccagtgggt ggtccatctc agttttctac catctattcc ctcaacatgg aacacaatcg   1260

aatcaacaaa attccatttg gaattttctc cagagcaaaa gtattaagta agctgaatat   1320

gaaggacaat cagttaacat cacttccctt ggattttgga acttggacca gtatggtaga   1380

attgaattta gccactaatc agctcacaaa gatccctgag gatgtgtctg gtctcgtttc   1440

tcttgaggtt cttatcttat caaacaatct tctaaagaag cttccccatg gtcttggaaa   1500

ccttaggaag ttaagagagt tggatctaga agagaacaaa ttggaatcct tgccaaatga   1560

aattgcatat cttaaggatt tacagaaatt agtcttgaca aacaaccagt tgaccactct   1620

tcccagaggc attggtcacc ttactaatct cacacatctg ggccttggag agaacctact   1680

tactcacctt cctgaagaaa ttggtacact ggagaaccta gaagaactgt atttgaatga   1740

caaccccaac ctgcatagcc ttccctttga gctggcactc tgcagcaagc tttcaatcat   1800

gagtattgag aactgtccac tcagtcacct tccacctcag attgttgctg gggggccttc   1860

tttcatcatt cagttcttaa agatgcaggg tccatatcgt gccatggtct gatataaatc   1920

tgctggtccc acacactgtt caaaaataga ctgccattaa tgtttcttat ctatatctgt   1980

atctatttat gtagatattg gtatatggca gatttataaa aattgcatta tgtgtttctg   2040

ctaatagagg aatcatagcc atttagaatt ttttttaaat tctgtacaaa aggcttatat   2100

aagttttctt tgctgaattt gatggatgtt tttctgttgt gtaatctgat atgccagttt   2160

gcttaaaaca tttgccaaca cattatgaag ttattaaatt taagggacag aggtagtata   2220

gttagatata ctttctctta ggaaaaataa tgggcaaaaa tttttgttgc aacttttcat   2280

atatattttc cccttaccaa ttgttttatc cttatagtat tgtaggccct gaaagtagaa   2340

tttttcttta acttattttg agatttgaga tttaaatttt atgtattgtt tacagtcaga   2400

gtaaatcact ggatttcttt tgtttgtttt gatttgctct gttttattca gtcaaatcta   2460

gagtttgaat cctctgctaa agaatttgca tccactggtg taaacagtga aaggtatttg   2520

cttgttgaaa aaaaaaactg gcaaagtgaa aagatacagt caaaaatcta gaatttcttt   2580

aattttgctt ctctgacgag ttgtgaagca aaatacctga agtgagtctt tgggtagggg   2640

aagggtattg agaccttttc tagtatgaat attttttaag tttgggggaa gagaaacttg   2700

cagtgaaaag gagttttttc attcctgaaa gttgcagatc cacaaaacta acaggataat   2760

tgggcaaata aattacatat aaacacacac aatctatata tgtatataca atgctatata   2820

gatatgtatt tattatatca taaactacag taggtaactt taaggatttc ttcctatcct   2880

tgtacaatga catgaatgtc tttctttgaa aactgcaatg tatgtatgtt tcaaggttat   2940

ttaacagtgt actatggttt tatatcttga cttgccttgt acatctttca attctggaat   3000

atctgtgtct aagcacaata tcttcacact gtgctgtatt gctgctgaac taaatgcact   3060

tttccccaca tatggggcac tggcttcaaa caattcagtt cagtatcatt acttttaatc   3120

tcatctttcc tttcttggta gttgttaata cagttatgga aaagaggcac attgcataga   3180

agccattggg gagttcagtg gaagttctgt aagatgtgca tgtactattt gatgcgtttt   3240

ctttgcttca ctgcttttaa tacttagcag tattgttggt ctaagtcaat ttgattattg   3300

aggagtctca gagcaaggtg cgttctagat gtcatcctaa aaaacacttc atatataatt   3360

aatcactatt ttgtataatt acatattgct gcttgtgtgt tttttttttt ttccatttag   3420

ttgggcgttg tgttttacac aaaaccattt ttgaattaag gctatgatat taagatagaa   3480

atttggactg ttgttctgct tttcctggca ctcaaattca tgactagttt tgaggtcaaa   3540

cctatgttcg taatgagaga ttttataagg atcaactaag aaatggaagg caggtgaaga   3600

tataaaaccc tagaatgctt aaatgtgctg taaaactatt gtagatgtca ctggatttta   3660

ccaagtaata tcctttcttt tttttttccc cccatctgct gtggcttttc agttaaaatt   3720

ttgtttataa aaggaatttg tttattacag ctctacctag a                       3761


<210>  7400
<211>  434
<212>  PRT
<213>  Homo sapiens

<400>  7400

Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser Leu Pro Asp Ser 
1               5                   10                  15


Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu Arg His Asn Lys 
            20                  25                  30


Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp Ser Leu Thr Thr 
        35                  40                  45


Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu Lys Asp Ile Lys 
    50                  55                  60


Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu Asn Lys Ile Lys 
65                  70                  75                  80


Gln Leu Pro Ala Glu Ile Gly Glu Leu Cys Asn Leu Ile Thr Leu Asp 
                85                  90                  95


Val Ala His Asn Gln Leu Glu His Leu Pro Lys Glu Ile Gly Asn Cys 
            100                 105                 110


Thr Gln Ile Thr Asn Leu Asp Leu Gln His Asn Glu Leu Leu Asp Leu 
        115                 120                 125


Pro Asp Thr Ile Gly Asn Leu Ser Ser Leu Ser Arg Leu Gly Leu Arg 
    130                 135                 140


Tyr Asn Arg Leu Ser Ala Ile Pro Arg Ser Leu Ala Lys Cys Ser Ala 
145                 150                 155                 160


Leu Glu Glu Leu Asn Leu Glu Asn Asn Asn Ile Ser Thr Leu Pro Glu 
                165                 170                 175


Ser Leu Leu Ser Ser Leu Val Lys Leu Asn Ser Leu Thr Leu Ala Arg 
            180                 185                 190


Asn Cys Phe Gln Leu Tyr Pro Val Gly Gly Pro Ser Gln Phe Ser Thr 
        195                 200                 205


Ile Tyr Ser Leu Asn Met Glu His Asn Arg Ile Asn Lys Ile Pro Phe 
    210                 215                 220


Gly Ile Phe Ser Arg Ala Lys Val Leu Ser Lys Leu Asn Met Lys Asp 
225                 230                 235                 240


Asn Gln Leu Thr Ser Leu Pro Leu Asp Phe Gly Thr Trp Thr Ser Met 
                245                 250                 255


Val Glu Leu Asn Leu Ala Thr Asn Gln Leu Thr Lys Ile Pro Glu Asp 
            260                 265                 270


Val Ser Gly Leu Val Ser Leu Glu Val Leu Ile Leu Ser Asn Asn Leu 
        275                 280                 285


Leu Lys Lys Leu Pro His Gly Leu Gly Asn Leu Arg Lys Leu Arg Glu 
    290                 295                 300


Leu Asp Leu Glu Glu Asn Lys Leu Glu Ser Leu Pro Asn Glu Ile Ala 
305                 310                 315                 320


Tyr Leu Lys Asp Leu Gln Lys Leu Val Leu Thr Asn Asn Gln Leu Thr 
                325                 330                 335


Thr Leu Pro Arg Gly Ile Gly His Leu Thr Asn Leu Thr His Leu Gly 
            340                 345                 350


Leu Gly Glu Asn Leu Leu Thr His Leu Pro Glu Glu Ile Gly Thr Leu 
        355                 360                 365


Glu Asn Leu Glu Glu Leu Tyr Leu Asn Asp Asn Pro Asn Leu His Ser 
    370                 375                 380


Leu Pro Phe Glu Leu Ala Leu Cys Ser Lys Leu Ser Ile Met Ser Ile 
385                 390                 395                 400


Glu Asn Cys Pro Leu Ser His Leu Pro Pro Gln Ile Val Ala Gly Gly 
                405                 410                 415


Pro Ser Phe Ile Ile Gln Phe Leu Lys Met Gln Gly Pro Tyr Arg Ala 
            420                 425                 430


Met Val 



<210>  7401
<211>  1893
<212>  DNA
<213>  Homo sapiens

<400>  7401
ggaggaggaa gaggaggaag gagggcgagc gaggaggatg gcggagtcgg ggctcctgac     60

gcattgttta caataaccaa gatatgaaat caacctatgt cttcattgat ggaagaatac    120

acacagaaaa tgtgacgttc agccttcaaa tctaggaaat cctgatattg gtgacatgat    180

ctgatcttgg cccactgcaa cctctgcctc ccaggttcaa gcgatcctcc cacctcagcc    240

tcccaggaac tctaatgaat cattgattga ccagcactat tttaccagtt ggaatgaatg    300

atcagaaatg ggcatagtgc ttttagatcc aacatgtaac agatggatgt tactccatgc    360

tgattacttc ttcaagccag tacttttttg attgtgtagg atctttgtct cttcatcttt    420

gaattcaatt actggaaaat aaaaggagtt catgtagttt ttgtccaggc ttgagtcacc    480

atgagtagta gtttaggaaa agaaaaagac tctaaagaaa aagatcccaa agtaccatca    540

gccaaggaaa gagaaaagga ggcaaaagcc tctggaggtt ttgggaaaga gagcaaagaa    600

aaagaaccta agaccaaagg gaaagatgcc aaagatggaa agaaggactc cagtgctgcc    660

caaccagggg tggcattttc agttgacaat acgatcaaac ggccaaaccc agcacctggg    720

actagaaaaa aatccagcaa tgcagaggtg attaaagagc tcaacaaatg ccgggaagag    780

aattcaatgc gtttggactt atccaagaga tctatacaca tattgccatc atcaatcaaa    840

gagttgactc aattaacaga actttattta tacagtaaca aattgcagtc cctcccagca    900

gaggtgggat gtttagtaaa tctcatgaca ctggctctaa gtgaaaattc acttaccagt    960

ttgcctgact ctcttgataa cttgaagaag ctgcggatgc ttgatttacg gcataataaa   1020

ctgagagaaa ttccttcagt ggtgtatagg ctggattctc tcaccactct ttaccttcgc   1080

tttaatcgta taactactgt ggaaaaggac atcaaaaact tgtcaaaact cagcatgctt   1140

agcattcgag agaacaaaat taaacaacta cctgctgaaa ttggtaagag gccttggatt   1200

attattattt gtagtatttg ttatgctaaa taattttgag tgctttctca tatcaaaaaa   1260

tgcctgatac ttgcctaaaa acagcttatt tctaaattac aactttttta tggtttactt   1320

tattccattt tcagcactgt taatagtaca tggcttgaaa ttgtttcata gacttaaaaa   1380

gtgagttaga aaatagatgt aattagatct ttcccacaca aacctaatct ttaactttca   1440

ttggagaata agtaaattta aagaagaaaa gatgtttgcc taattttcaa gttgttgctg   1500

tgtttaaagt atctgttgat acaattttat tagatatatg aaaactacat tttctcattc   1560

tctgactttt ccacctttat ctgaaagatg tttaaattca catcactttc tacctaattt   1620

accacaaaag gttgacaaat cagagcctta caaaagagca gtgtcataag aaatagaaaa   1680

aaaatttttt tttgcatctt gaaagtactt acatgtttat taaaaataac acaagaattt   1740

agaagggtag aagaaacgtc acctgtagtg aatgcagcac tgttaccatt ttgctaattt   1800

tcattccagt ctttcacata aagctaactt gtactaaaac aaagaaaatg ttttttaaag   1860

gctggtagta ggagaaaaaa atagggaata taa                                1893


<210>  7402
<211>  250
<212>  PRT
<213>  Homo sapiens

<400>  7402

Met Ser Ser Ser Leu Gly Lys Glu Lys Asp Ser Lys Glu Lys Asp Pro 
1               5                   10                  15


Lys Val Pro Ser Ala Lys Glu Arg Glu Lys Glu Ala Lys Ala Ser Gly 
            20                  25                  30


Gly Phe Gly Lys Glu Ser Lys Glu Lys Glu Pro Lys Thr Lys Gly Lys 
        35                  40                  45


Asp Ala Lys Asp Gly Lys Lys Asp Ser Ser Ala Ala Gln Pro Gly Val 
    50                  55                  60


Ala Phe Ser Val Asp Asn Thr Ile Lys Arg Pro Asn Pro Ala Pro Gly 
65                  70                  75                  80


Thr Arg Lys Lys Ser Ser Asn Ala Glu Val Ile Lys Glu Leu Asn Lys 
                85                  90                  95


Cys Arg Glu Glu Asn Ser Met Arg Leu Asp Leu Ser Lys Arg Ser Ile 
            100                 105                 110


His Ile Leu Pro Ser Ser Ile Lys Glu Leu Thr Gln Leu Thr Glu Leu 
        115                 120                 125


Tyr Leu Tyr Ser Asn Lys Leu Gln Ser Leu Pro Ala Glu Val Gly Cys 
    130                 135                 140


Leu Val Asn Leu Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser 
145                 150                 155                 160


Leu Pro Asp Ser Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu 
                165                 170                 175


Arg His Asn Lys Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp 
            180                 185                 190


Ser Leu Thr Thr Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu 
        195                 200                 205


Lys Asp Ile Lys Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu 
    210                 215                 220


Asn Lys Ile Lys Gln Leu Pro Ala Glu Ile Gly Lys Arg Pro Trp Ile 
225                 230                 235                 240


Ile Ile Ile Cys Ser Ile Cys Tyr Ala Lys 
                245                 250


<210>  7403
<211>  3976
<212>  DNA
<213>  Homo sapiens

<400>  7403
agccggcgcg agggcgcggg ccgggggccc ccggcggaca gtctctctcc tctcggctcc     60

ctgggccccc gggcccagtc cgcagggcgc cccgagtcgt gtaaatcgtt ggcgagggcc    120

cgggcgcagc ggcggtcata cagggaactc taatgaatca ttgattgacc agcactattt    180

taccagttgg aatgaatgat cagaaatggg catagtgctt ttagatccaa catgtaacag    240

atggatgtta ctccatgctg attacttctt caagccagta cttttttgat tgtgtaggat    300

ctttgtctct tcatctttga attcaattac tggaaaataa aaggagttca tgtagttttt    360

gtccaggctt gagtcaccat gagtagtagt ttaggaaaag aaaaagactc taaagaaaaa    420

gatcccaaag taccatcagc caaggaaaga gaaaaggagg caaaagcctc tggaggtttt    480

gggaaagaga gcaaagaaaa agaacctaag accaaaggga aagatgccaa agatggaaag    540

aaggactcca gtgctgccca accaggggtg gcattttcag ttgacaatac gatcaaacgg    600

ccaaacccag cacctgggac tagaaaaaaa tccagcaatg cagaggtgat taaagagctc    660

aacaaatgcc gggaagagaa ttcaatgcgt ttggacttat ccaagagatc tatacacata    720

ttgccatcat caatcaaaga gttgactcaa ttaacagaac tttatttata cagtaacaaa    780

ttgcagtccc tcccagcaga ggtgggatgt ttagtaaatc tcatgacact ggctctaagt    840

gaaaattcac ttaccagttt gcctgactct cttgataact tgaagaagct gcggatgctt    900

gatttacggc ataataaact gagagaaatt ccttcagtgg tgtataggct ggattctctc    960

accactcttt accttcgctt taatcgtata actactgtgg aaaaggacat caaaaacttg   1020

tcaaaactca gcatgcttag cattcgagag aacaaaatta aacaactacc tgctgaaatt   1080

ggtgaattat gtaacctcat tacgctggat gtagctcaca atcaacttga acaccttcca   1140

aaggagattg gaaactgtac acagataacc aaccttgact tgcagcacaa tgaactgcta   1200

gacctcccag atactatagg aaacctgtcc agtttaagtc gtcttggtct gagatataac   1260

agactgtcag caatacccag atcattagca aaatgcagtg cacttgaaga attaaattta   1320

gagaacaata acatttctac tttaccagag agtcttttat caagtcttgt gaaactgaat   1380

agtttgacct tagctagaaa ttgcttccag ttgtatccag tgggtggtcc atctcagttt   1440

tctaccatct attccctcaa catggaacac aatcgaatca acaaaattcc atttggaatt   1500

ttctccagag caaaagtatt aagtaagctg aatatgaagg acaatcagtt aacatcactt   1560

cccttggatt ttggaacttg gaccagtatg gtagaattga atttagccac taatcagctc   1620

acaaagatcc ctgaggatgt gtctggtctc gtttctcttg aggttcttat cttatcaaac   1680

aatcttctaa agaagcttcc ccatggtctt ggaaacctta ggaagttaag agagttggat   1740

ctagaagaga acaaattgga atccttgcca aatgaaattg catatcttaa ggatttacag   1800

aaattagtct tgacaaacaa ccagttgacc actcttccca gaggcattgg tcaccttact   1860

aatctcacac atctgggcct tggagagaac ctacttactc accttcctga agaaattggt   1920

acactggaga acctagaaga actgtatttg aatgacaacc ccaacctgca tagccttccc   1980

tttgagctgg cactctgcag caagctttca atcatgagta ttgagaactg tccactcagt   2040

caccttccac ctcagattgt tgctgggggg ccttctttca tcattcagtt cttaaagatg   2100

cagggtccat atcgtgccat ggtctgatat aaatctgctg gtcccacaca ctgttcaaaa   2160

atagactgcc attaatgttt cttatctata tctgtatcta tttatgtaga tattggtata   2220

tggcagattt ataaaaattg cattatgtgt ttctgctaat agaggaatca tagccattta   2280

gaattttttt taaattctgt acaaaaggct tatataagtt ttctttgctg aatttgatgg   2340

atgtttttct gttgtgtaat ctgatatgcc agtttgctta aaacatttgc caacacatta   2400

tgaagttatt aaatttaagg gacagaggta gtatagttag atatactttc tcttaggaaa   2460

aataatgggc aaaaattttt gttgcaactt ttcatatata ttttcccctt accaattgtt   2520

ttatccttat agtattgtag gccctgaaag tagaattttt ctttaactta ttttgagatt   2580

tgagatttaa attttatgta ttgtttacag tcagagtaaa tcactggatt tcttttgttt   2640

gttttgattt gctctgtttt attcagtcaa atctagagtt tgaatcctct gctaaagaat   2700

ttgcatccac tggtgtaaac agtgaaaggt atttgcttgt tgaaaaaaaa aactggcaaa   2760

gtgaaaagat acagtcaaaa atctagaatt tctttaattt tgcttctctg acgagttgtg   2820

aagcaaaata cctgaagtga gtctttgggt aggggaaggg tattgagacc ttttctagta   2880

tgaatatttt ttaagtttgg gggaagagaa acttgcagtg aaaaggagtt ttttcattcc   2940

tgaaagttgc agatccacaa aactaacagg ataattgggc aaataaatta catataaaca   3000

cacacaatct atatatgtat atacaatgct atatagatat gtatttatta tatcataaac   3060

tacagtaggt aactttaagg atttcttcct atccttgtac aatgacatga atgtctttct   3120

ttgaaaactg caatgtatgt atgtttcaag gttatttaac agtgtactat ggttttatat   3180

cttgacttgc cttgtacatc tttcaattct ggaatatctg tgtctaagca caatatcttc   3240

acactgtgct gtattgctgc tgaactaaat gcacttttcc ccacatatgg ggcactggct   3300

tcaaacaatt cagttcagta tcattacttt taatctcatc tttcctttct tggtagttgt   3360

taatacagtt atggaaaaga ggcacattgc atagaagcca ttggggagtt cagtggaagt   3420

tctgtaagat gtgcatgtac tatttgatgc gttttctttg cttcactgct tttaatactt   3480

agcagtattg ttggtctaag tcaatttgat tattgaggag tctcagagca aggtgcgttc   3540

tagatgtcat cctaaaaaac acttcatata taattaatca ctattttgta taattacata   3600

ttgctgcttg tgtgtttttt tttttttcca tttagttggg cgttgtgttt tacacaaaac   3660

catttttgaa ttaaggctat gatattaaga tagaaatttg gactgttgtt ctgcttttcc   3720

tggcactcaa attcatgact agttttgagg tcaaacctat gttcgtaatg agagatttta   3780

taaggatcaa ctaagaaatg gaaggcaggt gaagatataa aaccctagaa tgcttaaatg   3840

tgctgtaaaa ctattgtaga tgtcactgga ttttaccaag taatatcctt tctttttttt   3900

ttccccccat ctgctgtggc ttttcagtta aaattttgtt tataaaagga atttgtttat   3960

tacagctcta cctaga                                                   3976


<210>  7404
<211>  582
<212>  PRT
<213>  Homo sapiens

<400>  7404

Met Ser Ser Ser Leu Gly Lys Glu Lys Asp Ser Lys Glu Lys Asp Pro 
1               5                   10                  15


Lys Val Pro Ser Ala Lys Glu Arg Glu Lys Glu Ala Lys Ala Ser Gly 
            20                  25                  30


Gly Phe Gly Lys Glu Ser Lys Glu Lys Glu Pro Lys Thr Lys Gly Lys 
        35                  40                  45


Asp Ala Lys Asp Gly Lys Lys Asp Ser Ser Ala Ala Gln Pro Gly Val 
    50                  55                  60


Ala Phe Ser Val Asp Asn Thr Ile Lys Arg Pro Asn Pro Ala Pro Gly 
65                  70                  75                  80


Thr Arg Lys Lys Ser Ser Asn Ala Glu Val Ile Lys Glu Leu Asn Lys 
                85                  90                  95


Cys Arg Glu Glu Asn Ser Met Arg Leu Asp Leu Ser Lys Arg Ser Ile 
            100                 105                 110


His Ile Leu Pro Ser Ser Ile Lys Glu Leu Thr Gln Leu Thr Glu Leu 
        115                 120                 125


Tyr Leu Tyr Ser Asn Lys Leu Gln Ser Leu Pro Ala Glu Val Gly Cys 
    130                 135                 140


Leu Val Asn Leu Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser 
145                 150                 155                 160


Leu Pro Asp Ser Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu 
                165                 170                 175


Arg His Asn Lys Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp 
            180                 185                 190


Ser Leu Thr Thr Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu 
        195                 200                 205


Lys Asp Ile Lys Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu 
    210                 215                 220


Asn Lys Ile Lys Gln Leu Pro Ala Glu Ile Gly Glu Leu Cys Asn Leu 
225                 230                 235                 240


Ile Thr Leu Asp Val Ala His Asn Gln Leu Glu His Leu Pro Lys Glu 
                245                 250                 255


Ile Gly Asn Cys Thr Gln Ile Thr Asn Leu Asp Leu Gln His Asn Glu 
            260                 265                 270


Leu Leu Asp Leu Pro Asp Thr Ile Gly Asn Leu Ser Ser Leu Ser Arg 
        275                 280                 285


Leu Gly Leu Arg Tyr Asn Arg Leu Ser Ala Ile Pro Arg Ser Leu Ala 
    290                 295                 300


Lys Cys Ser Ala Leu Glu Glu Leu Asn Leu Glu Asn Asn Asn Ile Ser 
305                 310                 315                 320


Thr Leu Pro Glu Ser Leu Leu Ser Ser Leu Val Lys Leu Asn Ser Leu 
                325                 330                 335


Thr Leu Ala Arg Asn Cys Phe Gln Leu Tyr Pro Val Gly Gly Pro Ser 
            340                 345                 350


Gln Phe Ser Thr Ile Tyr Ser Leu Asn Met Glu His Asn Arg Ile Asn 
        355                 360                 365


Lys Ile Pro Phe Gly Ile Phe Ser Arg Ala Lys Val Leu Ser Lys Leu 
    370                 375                 380


Asn Met Lys Asp Asn Gln Leu Thr Ser Leu Pro Leu Asp Phe Gly Thr 
385                 390                 395                 400


Trp Thr Ser Met Val Glu Leu Asn Leu Ala Thr Asn Gln Leu Thr Lys 
                405                 410                 415


Ile Pro Glu Asp Val Ser Gly Leu Val Ser Leu Glu Val Leu Ile Leu 
            420                 425                 430


Ser Asn Asn Leu Leu Lys Lys Leu Pro His Gly Leu Gly Asn Leu Arg 
        435                 440                 445


Lys Leu Arg Glu Leu Asp Leu Glu Glu Asn Lys Leu Glu Ser Leu Pro 
    450                 455                 460


Asn Glu Ile Ala Tyr Leu Lys Asp Leu Gln Lys Leu Val Leu Thr Asn 
465                 470                 475                 480


Asn Gln Leu Thr Thr Leu Pro Arg Gly Ile Gly His Leu Thr Asn Leu 
                485                 490                 495


Thr His Leu Gly Leu Gly Glu Asn Leu Leu Thr His Leu Pro Glu Glu 
            500                 505                 510


Ile Gly Thr Leu Glu Asn Leu Glu Glu Leu Tyr Leu Asn Asp Asn Pro 
        515                 520                 525


Asn Leu His Ser Leu Pro Phe Glu Leu Ala Leu Cys Ser Lys Leu Ser 
    530                 535                 540


Ile Met Ser Ile Glu Asn Cys Pro Leu Ser His Leu Pro Pro Gln Ile 
545                 550                 555                 560


Val Ala Gly Gly Pro Ser Phe Ile Ile Gln Phe Leu Lys Met Gln Gly 
                565                 570                 575


Pro Tyr Arg Ala Met Val 
            580


<210>  7405
<211>  1691
<212>  DNA
<213>  Homo sapiens

<400>  7405
gtaaatcgtt ggcgagggcc cgggcgcagc ggcggtcata cagggaactc taatgaatca     60

ttgattgacc agcactattt taccagttgg aatgaatgat cagaaatggg catagtgctt    120

ttagatccaa catgtaacag atggatgtta ctccatgctg attacttctt caagccagta    180

cttttttgat tgtgtaggat ctttgtctct tcatctttga attcaattac tggaaaataa    240

aaggagttca tgtagttttt gtccaggctt gagtcaccat gagtagtagt ttaggaaaag    300

aaaaagactc taaagaaaaa gatcccaaag taccatcagc caaggaaaga gaaaaggagg    360

caaaagcctc tggaggtttt gggaaagaga gcaaagaaaa agaacctaag accaaaggga    420

aagatgccaa agatggaaag aaggactcca gtgctgccca accaggggtg gcattttcag    480

ttgacaatac gatcaaacgg ccaaacccag cacctgggac tagaaaaaaa tccagcaatg    540

cagaggtgat taaagagctc aacaaatgcc gggaagagaa ttcaatgcgt ttggacttat    600

ccaagagatc tatacacata ttgccatcat caatcaaaga gttgactcaa ttaacagaac    660

tttatttata cagtaacaaa ttgcagtccc tcccagcaga ggtgggatgt ttagtaaatc    720

tcatgacact ggctctaagt gaaaattcac ttaccagttt gcctgactct cttgataact    780

tgaagaagct gcggatgctt gatttacggc ataataaact gagagaaatt ccttcagtgg    840

tgtataggct ggattctctc accactcttt accttcgctt taatcgtata actactgtgg    900

aaaaggacat caaaaacttg tcaaaactca gcatgcttag cattcgagag aacaaaatta    960

aacaactacc tgctgaaatt ggtaagaggc cttggattat tattatttgt agtatttgtt   1020

atgctaaata attttgagtg ctttctcata tcaaaaaatg cctgatactt gcctaaaaac   1080

agcttatttc taaattacaa cttttttatg gtttacttta ttccattttc agcactgtta   1140

atagtacatg gcttgaaatt gtttcataga cttaaaaagt gagttagaaa atagatgtaa   1200

ttagatcttt cccacacaaa cctaatcttt aactttcatt ggagaataag taaatttaaa   1260

gaagaaaaga tgtttgccta attttcaagt tgttgctgtg tttaaagtat ctgttgatac   1320

aattttatta gatatatgaa aactacattt tctcattctc tgacttttcc acctttatct   1380

gaaagatgtt taaattcaca tcactttcta cctaatttac cacaaaaggt tgacaaatca   1440

gagccttaca aaagagcagt gtcataagaa atagaaaaaa aatttttttt tgcatcttga   1500

aagtacttac atgtttatta aaaataacac aagaatttag aagggtagaa gaaacgtcac   1560

ctgtagtgaa tgcagcactg ttaccatttt gctaattttc attccagtct ttcacataaa   1620

gctaacttgt actaaaacaa agaaaatgtt ttttaaaggc tggtagtagg agaaaaaaat   1680

agggaatata a                                                        1691


<210>  7406
<211>  250
<212>  PRT
<213>  Homo sapiens

<400>  7406

Met Ser Ser Ser Leu Gly Lys Glu Lys Asp Ser Lys Glu Lys Asp Pro 
1               5                   10                  15


Lys Val Pro Ser Ala Lys Glu Arg Glu Lys Glu Ala Lys Ala Ser Gly 
            20                  25                  30


Gly Phe Gly Lys Glu Ser Lys Glu Lys Glu Pro Lys Thr Lys Gly Lys 
        35                  40                  45


Asp Ala Lys Asp Gly Lys Lys Asp Ser Ser Ala Ala Gln Pro Gly Val 
    50                  55                  60


Ala Phe Ser Val Asp Asn Thr Ile Lys Arg Pro Asn Pro Ala Pro Gly 
65                  70                  75                  80


Thr Arg Lys Lys Ser Ser Asn Ala Glu Val Ile Lys Glu Leu Asn Lys 
                85                  90                  95


Cys Arg Glu Glu Asn Ser Met Arg Leu Asp Leu Ser Lys Arg Ser Ile 
            100                 105                 110


His Ile Leu Pro Ser Ser Ile Lys Glu Leu Thr Gln Leu Thr Glu Leu 
        115                 120                 125


Tyr Leu Tyr Ser Asn Lys Leu Gln Ser Leu Pro Ala Glu Val Gly Cys 
    130                 135                 140


Leu Val Asn Leu Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser 
145                 150                 155                 160


Leu Pro Asp Ser Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu 
                165                 170                 175


Arg His Asn Lys Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp 
            180                 185                 190


Ser Leu Thr Thr Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu 
        195                 200                 205


Lys Asp Ile Lys Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu 
    210                 215                 220


Asn Lys Ile Lys Gln Leu Pro Ala Glu Ile Gly Lys Arg Pro Trp Ile 
225                 230                 235                 240


Ile Ile Ile Cys Ser Ile Cys Tyr Ala Lys 
                245                 250


<210>  7407
<211>  652
<212>  DNA
<213>  Homo sapiens

<400>  7407
tttcccaagg ggcagccgaa gatggcagag gtgcaggtcc tggtgcttga tggtcgaggc     60

catctcctgg gccgcctggc gaccatcgtg gctaaacagg tactgctggg ccggaaggtg    120

gtggtcgtac gctgcaaagg catcaacatt tctggcaatt tctacagaaa caagttgaag    180

tacttggctt tcctccgcaa gcggatgaac accaaccctt tccgacgccc ctaccacttc    240

cgggccccca gccccatctt ctggctgact gtgcgaagta tgctgcccca caagaccaag    300

cgaggccagg ccgctctgga ccgcctcaag gtgtttgact gcatcccacc gccttacgac    360

aagaaaaagc ggatggtggt tcctgctgcc ctcaaggttg tgcgtctgaa gcctacaaga    420

aagtttgcct atctggggca cctggctcac gaggttggct ggaagtacca cgcagtgaca    480

gccaccctgg aggagaagag gaaagagaaa gccaaaatcc actaccggaa gaagaaagag    540

ctcataagcc tacggaaaca ggccaagagg aacatggaga agaaaactga caaatacaca    600

gaggtcctca agacccacgg actcctggtc tgagcccaat aaagactgtt aa            652


<210>  7408
<211>  203
<212>  PRT
<213>  Homo sapiens

<400>  7408

Met Ala Glu Val Gln Val Leu Val Leu Asp Gly Arg Gly His Leu Leu 
1               5                   10                  15


Gly Arg Leu Ala Thr Ile Val Ala Lys Gln Val Leu Leu Gly Arg Lys 
            20                  25                  30


Val Val Val Val Arg Cys Lys Gly Ile Asn Ile Ser Gly Asn Phe Tyr 
        35                  40                  45


Arg Asn Lys Leu Lys Tyr Leu Ala Phe Leu Arg Lys Arg Met Asn Thr 
    50                  55                  60


Asn Pro Phe Arg Arg Pro Tyr His Phe Arg Ala Pro Ser Pro Ile Phe 
65                  70                  75                  80


Trp Leu Thr Val Arg Ser Met Leu Pro His Lys Thr Lys Arg Gly Gln 
                85                  90                  95


Ala Ala Leu Asp Arg Leu Lys Val Phe Asp Cys Ile Pro Pro Pro Tyr 
            100                 105                 110


Asp Lys Lys Lys Arg Met Val Val Pro Ala Ala Leu Lys Val Val Arg 
        115                 120                 125


Leu Lys Pro Thr Arg Lys Phe Ala Tyr Leu Gly His Leu Ala His Glu 
    130                 135                 140


Val Gly Trp Lys Tyr His Ala Val Thr Ala Thr Leu Glu Glu Lys Arg 
145                 150                 155                 160


Lys Glu Lys Ala Lys Ile His Tyr Arg Lys Lys Lys Glu Leu Ile Ser 
                165                 170                 175


Leu Arg Lys Gln Ala Lys Arg Asn Met Glu Lys Lys Thr Asp Lys Tyr 
            180                 185                 190


Thr Glu Val Leu Lys Thr His Gly Leu Leu Val 
        195                 200


<210>  7409
<211>  575
<212>  DNA
<213>  Homo sapiens

<400>  7409
caaggggcag ccgaagatgg cagaggtgca ggtcctggtg cttgatggtc gaggccatct     60

cctgggccgc ctggcgacca tcgtggctaa acaggtactg ctgggccgga aggtggtggt    120

cgtacgctgc aaaggcatca acatttctgg caatttctac agaaacaagt tgaagtactt    180

ggctttcctc cgcaagcgga tgaacaccaa ccctttccga cgcccctacc acttccgggc    240

ccccagcccc atcttctggc tgactgtgcg aagtatgctg ccccacaaga ccaagcgagg    300

ccaggccgct ctggaccgcc tcaaggttgt gcgtctgaag cctacaagaa agtttgccta    360

tctggggcac ctggctcacg aggttggctg gaagtaccac gcagtgacag ccaccctgga    420

ggagaagagg aaagagaaag ccaaaatcca ctaccggaag aagaaagagc tcataagcct    480

acggaaacag gccaagagga acatggagaa gaaaactgac aaatacacag aggtcctcaa    540

gacccacgga ctcctggtct gagcccaata aagac                               575


<210>  7410
<211>  181
<212>  PRT
<213>  Homo sapiens

<400>  7410

Met Ala Glu Val Gln Val Leu Val Leu Asp Gly Arg Gly His Leu Leu 
1               5                   10                  15


Gly Arg Leu Ala Thr Ile Val Ala Lys Gln Val Leu Leu Gly Arg Lys 
            20                  25                  30


Val Val Val Val Arg Cys Lys Gly Ile Asn Ile Ser Gly Asn Phe Tyr 
        35                  40                  45


Arg Asn Lys Leu Lys Tyr Leu Ala Phe Leu Arg Lys Arg Met Asn Thr 
    50                  55                  60


Asn Pro Phe Arg Arg Pro Tyr His Phe Arg Ala Pro Ser Pro Ile Phe 
65                  70                  75                  80


Trp Leu Thr Val Arg Ser Met Leu Pro His Lys Thr Lys Arg Gly Gln 
                85                  90                  95


Ala Ala Leu Asp Arg Leu Lys Val Val Arg Leu Lys Pro Thr Arg Lys 
            100                 105                 110


Phe Ala Tyr Leu Gly His Leu Ala His Glu Val Gly Trp Lys Tyr His 
        115                 120                 125


Ala Val Thr Ala Thr Leu Glu Glu Lys Arg Lys Glu Lys Ala Lys Ile 
    130                 135                 140


His Tyr Arg Lys Lys Lys Glu Leu Ile Ser Leu Arg Lys Gln Ala Lys 
145                 150                 155                 160


Arg Asn Met Glu Lys Lys Thr Asp Lys Tyr Thr Glu Val Leu Lys Thr 
                165                 170                 175


His Gly Leu Leu Val 
            180


<210>  7411
<211>  3695
<212>  DNA
<213>  Homo sapiens

<400>  7411
ggaactctaa tgaatcattg attgaccagc actattttac cagttggaat gaatgatcag     60

aaatgggcat agtgctttta gatccaacat gtaacagatg gatgttactc catgctgatt    120

acttcttcaa gccagtactt ttttgattgt gtaggatctt tgtctcttca tctttgaatt    180

caattactgg aaaataaaag gagttcatgt agtttttgtc caggcttgag tcaccatgag    240

tagtagttta ggaaaagaaa aagactctaa agaaaaagat cccaaagtac catcagccaa    300

ggaaagagaa aaggaggcaa aagcctctgg aggttttggg aaagagagca aagaaaaaga    360

acctaagacc aaagggaaag atgccaaaga tggaaagaag gactccagtg ctgcccaacc    420

aggggtggca ttttcagttg acaatacgat caaacggcca aacccagcac ctgggactag    480

aaaaaaatcc agcaatgcag aggtgattaa agagctcaac aaatgccggg aagagaattc    540

aatgcgtttg gacttatcca agagatctat acacatattg ccatcatcaa tcaaagagtt    600

gactcaatta acagaacttt atttatacag taacaaattg cagtccctcc cagcagaggt    660

gggatgttta gtaaatctca tgacactggc tctaagtgaa aattcactta ccagtttgcc    720

tgactctctt gataacttga agaagctgcg gatgcttgat ttacggcata ataaactgag    780

agaaattcct tcagtggtgt ataggctgga ttctctcacc actctttacc ttcgctttaa    840

tcgtataact actgtggaaa aggacatcaa aaacttgtca aaactcagca tgcttagcat    900

tcgagagaac aaaattaaac aactacctgc tgaaattgga aacctgtcca gtttaagtcg    960

tcttggtctg agatataaca gactgtcagc aatacccaga tcattagcaa aatgcagtgc   1020

acttgaagaa ttaaatttag agaacaataa catttctact ttaccagaga gtcttttatc   1080

aagtcttgtg aaactgaata gtttgacctt agctagaaat tgcttccagt tgtatccagt   1140

gggtggtcca tctcagtttt ctaccatcta ttccctcaac atggaacaca atcgaatcaa   1200

caaaattcca tttggaattt tctccagagc aaaagtatta agtaagctga atatgaagga   1260

caatcagtta acatcacttc ccttggattt tggaacttgg accagtatgg tagaattgaa   1320

tttagccact aatcagctca caaagatccc tgaggatgtg tctggtctcg tttctcttga   1380

ggttcttatc ttatcaaaca atcttctaaa gaagcttccc catggtcttg gaaaccttag   1440

gaagttaaga gagttggatc tagaagagaa caaattggaa tccttgccaa atgaaattgc   1500

atatcttaag gatttacaga aattagtctt gacaaacaac cagttgacca ctcttcccag   1560

aggcattggt caccttacta atctcacaca tctgggcctt ggagagaacc tacttactca   1620

ccttcctgaa gaaattggta cactggagaa cctagaagaa ctgtatttga atgacaaccc   1680

caacctgcat agccttccct ttgagctggc actctgcagc aagctttcaa tcatgagtat   1740

tgagaactgt ccactcagtc accttccacc tcagattgtt gctggggggc cttctttcat   1800

cattcagttc ttaaagatgc agggtccata tcgtgccatg gtctgatata aatctgctgg   1860

tcccacacac tgttcaaaaa tagactgcca ttaatgtttc ttatctatat ctgtatctat   1920

ttatgtagat attggtatat ggcagattta taaaaattgc attatgtgtt tctgctaata   1980

gaggaatcat agccatttag aatttttttt aaattctgta caaaaggctt atataagttt   2040

tctttgctga atttgatgga tgtttttctg ttgtgtaatc tgatatgcca gtttgcttaa   2100

aacatttgcc aacacattat gaagttatta aatttaaggg acagaggtag tatagttaga   2160

tatactttct cttaggaaaa ataatgggca aaaatttttg ttgcaacttt tcatatatat   2220

tttcccctta ccaattgttt tatccttata gtattgtagg ccctgaaagt agaatttttc   2280

tttaacttat tttgagattt gagatttaaa ttttatgtat tgtttacagt cagagtaaat   2340

cactggattt cttttgtttg ttttgatttg ctctgtttta ttcagtcaaa tctagagttt   2400

gaatcctctg ctaaagaatt tgcatccact ggtgtaaaca gtgaaaggta tttgcttgtt   2460

gaaaaaaaaa actggcaaag tgaaaagata cagtcaaaaa tctagaattt ctttaatttt   2520

gcttctctga cgagttgtga agcaaaatac ctgaagtgag tctttgggta ggggaagggt   2580

attgagacct tttctagtat gaatattttt taagtttggg ggaagagaaa cttgcagtga   2640

aaaggagttt tttcattcct gaaagttgca gatccacaaa actaacagga taattgggca   2700

aataaattac atataaacac acacaatcta tatatgtata tacaatgcta tatagatatg   2760

tatttattat atcataaact acagtaggta actttaagga tttcttccta tccttgtaca   2820

atgacatgaa tgtctttctt tgaaaactgc aatgtatgta tgtttcaagg ttatttaaca   2880

gtgtactatg gttttatatc ttgacttgcc ttgtacatct ttcaattctg gaatatctgt   2940

gtctaagcac aatatcttca cactgtgctg tattgctgct gaactaaatg cacttttccc   3000

cacatatggg gcactggctt caaacaattc agttcagtat cattactttt aatctcatct   3060

ttcctttctt ggtagttgtt aatacagtta tggaaaagag gcacattgca tagaagccat   3120

tggggagttc agtggaagtt ctgtaagatg tgcatgtact atttgatgcg ttttctttgc   3180

ttcactgctt ttaatactta gcagtattgt tggtctaagt caatttgatt attgaggagt   3240

ctcagagcaa ggtgcgttct agatgtcatc ctaaaaaaca cttcatatat aattaatcac   3300

tattttgtat aattacatat tgctgcttgt gtgttttttt ttttttccat ttagttgggc   3360

gttgtgtttt acacaaaacc atttttgaat taaggctatg atattaagat agaaatttgg   3420

actgttgttc tgcttttcct ggcactcaaa ttcatgacta gttttgaggt caaacctatg   3480

ttcgtaatga gagattttat aaggatcaac taagaaatgg aaggcaggtg aagatataaa   3540

accctagaat gcttaaatgt gctgtaaaac tattgtagat gtcactggat tttaccaagt   3600

aatatccttt cttttttttt tccccccatc tgctgtggct tttcagttaa aattttgttt   3660

ataaaaggaa tttgtttatt acagctctac ctaga                              3695


<210>  7412
<211>  536
<212>  PRT
<213>  Homo sapiens

<400>  7412

Met Ser Ser Ser Leu Gly Lys Glu Lys Asp Ser Lys Glu Lys Asp Pro 
1               5                   10                  15


Lys Val Pro Ser Ala Lys Glu Arg Glu Lys Glu Ala Lys Ala Ser Gly 
            20                  25                  30


Gly Phe Gly Lys Glu Ser Lys Glu Lys Glu Pro Lys Thr Lys Gly Lys 
        35                  40                  45


Asp Ala Lys Asp Gly Lys Lys Asp Ser Ser Ala Ala Gln Pro Gly Val 
    50                  55                  60


Ala Phe Ser Val Asp Asn Thr Ile Lys Arg Pro Asn Pro Ala Pro Gly 
65                  70                  75                  80


Thr Arg Lys Lys Ser Ser Asn Ala Glu Val Ile Lys Glu Leu Asn Lys 
                85                  90                  95


Cys Arg Glu Glu Asn Ser Met Arg Leu Asp Leu Ser Lys Arg Ser Ile 
            100                 105                 110


His Ile Leu Pro Ser Ser Ile Lys Glu Leu Thr Gln Leu Thr Glu Leu 
        115                 120                 125


Tyr Leu Tyr Ser Asn Lys Leu Gln Ser Leu Pro Ala Glu Val Gly Cys 
    130                 135                 140


Leu Val Asn Leu Met Thr Leu Ala Leu Ser Glu Asn Ser Leu Thr Ser 
145                 150                 155                 160


Leu Pro Asp Ser Leu Asp Asn Leu Lys Lys Leu Arg Met Leu Asp Leu 
                165                 170                 175


Arg His Asn Lys Leu Arg Glu Ile Pro Ser Val Val Tyr Arg Leu Asp 
            180                 185                 190


Ser Leu Thr Thr Leu Tyr Leu Arg Phe Asn Arg Ile Thr Thr Val Glu 
        195                 200                 205


Lys Asp Ile Lys Asn Leu Ser Lys Leu Ser Met Leu Ser Ile Arg Glu 
    210                 215                 220


Asn Lys Ile Lys Gln Leu Pro Ala Glu Ile Gly Asn Leu Ser Ser Leu 
225                 230                 235                 240


Ser Arg Leu Gly Leu Arg Tyr Asn Arg Leu Ser Ala Ile Pro Arg Ser 
                245                 250                 255


Leu Ala Lys Cys Ser Ala Leu Glu Glu Leu Asn Leu Glu Asn Asn Asn 
            260                 265                 270


Ile Ser Thr Leu Pro Glu Ser Leu Leu Ser Ser Leu Val Lys Leu Asn 
        275                 280                 285


Ser Leu Thr Leu Ala Arg Asn Cys Phe Gln Leu Tyr Pro Val Gly Gly 
    290                 295                 300


Pro Ser Gln Phe Ser Thr Ile Tyr Ser Leu Asn Met Glu His Asn Arg 
305                 310                 315                 320


Ile Asn Lys Ile Pro Phe Gly Ile Phe Ser Arg Ala Lys Val Leu Ser 
                325                 330                 335


Lys Leu Asn Met Lys Asp Asn Gln Leu Thr Ser Leu Pro Leu Asp Phe 
            340                 345                 350


Gly Thr Trp Thr Ser Met Val Glu Leu Asn Leu Ala Thr Asn Gln Leu 
        355                 360                 365


Thr Lys Ile Pro Glu Asp Val Ser Gly Leu Val Ser Leu Glu Val Leu 
    370                 375                 380


Ile Leu Ser Asn Asn Leu Leu Lys Lys Leu Pro His Gly Leu Gly Asn 
385                 390                 395                 400


Leu Arg Lys Leu Arg Glu Leu Asp Leu Glu Glu Asn Lys Leu Glu Ser 
                405                 410                 415


Leu Pro Asn Glu Ile Ala Tyr Leu Lys Asp Leu Gln Lys Leu Val Leu 
            420                 425                 430


Thr Asn Asn Gln Leu Thr Thr Leu Pro Arg Gly Ile Gly His Leu Thr 
        435                 440                 445


Asn Leu Thr His Leu Gly Leu Gly Glu Asn Leu Leu Thr His Leu Pro 
    450                 455                 460


Glu Glu Ile Gly Thr Leu Glu Asn Leu Glu Glu Leu Tyr Leu Asn Asp 
465                 470                 475                 480


Asn Pro Asn Leu His Ser Leu Pro Phe Glu Leu Ala Leu Cys Ser Lys 
                485                 490                 495


Leu Ser Ile Met Ser Ile Glu Asn Cys Pro Leu Ser His Leu Pro Pro 
            500                 505                 510


Gln Ile Val Ala Gly Gly Pro Ser Phe Ile Ile Gln Phe Leu Lys Met 
        515                 520                 525


Gln Gly Pro Tyr Arg Ala Met Val 
    530                 535


<210>  7413
<211>  3785
<212>  DNA
<213>  Homo sapiens

<400>  7413
ggagcagcag cagctccagc tcggtgcaga agcccagcag ccggcgtgcc gccgcccggc     60

cactccagcg ccttcttccc cgccttgcgc tcctgcccca actcgcgctg tcgtcggacc    120

ccggcccatc cagcagcgct cggcgcccac caggcggacg cccaggagaa cccctgcctc    180

cgtcgcggct cctggagagc tgatcgttca cctgccccgg cccgcctgag gacgggggtg    240

ccttcatgcg gcccccacac tcctcacccc gccgccgccg ccgtcccgga gctccgcaca    300

gtgtgcccca gccccagcag ggcgcacaac tttggaagtc tcgcggcgct ccgagaggcg    360

gcagagtccg cgccccagcc ccgggccggg ccgggccaga accgcagcgt ctgggggaag    420

ccagagagtc ggtaatcgct tcggggatgt aaggcgacag acataggacc cccgagctcg    480

catcagcacc cttcggctgc ctcccggggt gggggcgggc cccgcacacg gtaagacctc    540

ttgctttcgc tcaggctcaa gattcaagat acagatattg atatgtatat atatatttaa    600

tttcctgtca tccttccaag ttatcaggcc accgatgatt tttgttctcc cttcttgaag    660

aataaatctc tctttaccca tcggctctcc ctactctctc ccgccgctta gaaataaaac    720

ttggctgtat taggagctcg gagcaagaag gcgcccaccg agagcgtctg aagcgcgagc    780

caggcgcagt tcgcgggacc cgggccatgg gccgctagcg gtcctccagt tcgggcccgg    840

cctccctgcg gccccctccc tatgtgagcc gcagccaggc gagcggggcg ccggaggaag    900

aggaggaccc acgggcgccg ggccggaagg cagctggcag caggcccagg ccagcgggcg    960

cccgcgttca tgttccgcca ggagcagccg ttggccgagg gcagctttgc gcccatgggc   1020

tccctgcagc cggacgcggg caacgcgagc tggaacggga ccgaggcgcc ggggggcggc   1080

gcccgggcca ccccttactc cctgcaggtg acgctgacgc tggtgtgcct ggccggcctg   1140

ctcatgctgc tcaccgtgtt cggcaacgtg ctcgtcatca tcgccgtgtt cacgagccgc   1200

gcgctcaagg cgccccaaaa cctcttcctg gtgtctctgg cctcggccga catcctggtg   1260

gccacgctcg tcatcccttt ctcgctggcc aacgaggtca tgggctactg gtacttcggc   1320

aaggcttggt gcgagatcta cctggcgctc gacgtgctct tctgcacgtc gtccatcgtg   1380

cacctgtgcg ccatcagcct ggaccgctac tggtccatca cacaggccat cgagtacaac   1440

ctgaagcgca cgccgcgccg catcaaggcc atcatcatca ccgtgtgggt catctcggcc   1500

gtcatctcct tcccgccgct catctccatc gagaagaagg gcggcggcgg cggcccgcag   1560

ccggccgagc cgcgctgcga gatcaacgac cagaagtggt acgtcatctc gtcgtgcatc   1620

ggctccttct tcgctccctg cctcatcatg atcctggtct acgtgcgcat ctaccagatc   1680

gccaagcgtc gcacccgcgt gccacccagc cgccggggtc cggacgccgt cgccgcgccg   1740

ccggggggca ccgagcgcag gcccaacggt ctgggccccg agcgcagcgc gggcccgggg   1800

ggcgcagagg ccgaaccgct gcccacccag ctcaacggcg cccctggcga gcccgcgccg   1860

gccgggccgc gcgacaccga cgcgctggac ctggaggaga gctcgtcttc cgaccacgcc   1920

gagcggcctc cagggccccg cagacccgag cgcggtcccc ggggcaaagg caaggcccga   1980

gcgagccagg tgaagccggg cgacagcctg ccgcggcgcg ggccgggggc gacggggatc   2040

gggacgccgg ctgcagggcc gggggaggag cgcgtcgggg ctgccaaggc gtcgcgctgg   2100

cgcgggcggc agaaccgcga gaagcgcttc acgttcgtgc tggccgtggt catcggagtg   2160

ttcgtggtgt gctggttccc cttcttcttc acctacacgc tcacggccgt cgggtgctcc   2220

gtgccacgca cgctcttcaa attcttcttc tggttcggct actgcaacag ctcgttgaac   2280

ccggtcatct acaccatctt caaccacgat ttccgccgcg ccttcaagaa gatcctctgt   2340

cggggggaca ggaagcggat cgtgtgaggt ttccgctggc gcccgcgtag actcacgctg   2400

actgcaggca gcggggggca tcgaggggtg cttagcccca gggcactcag aaacccgggc   2460

gctgcctgct ctgcgtttcc tcgtctgggg tggctctgca gcctcctgcg ggcgggcgtc   2520

tgctgctcct acaagggaag cttcttgctg ccaggcccac acatccccag ttgttggttt   2580

ggccactctt gacctggagc catcttccta gtgggccacc cctaatcact attgcttcct   2640

aaaggtattt tcaccctctt cgcctggtac agccctcaca gctcttcaga gcaagcactg   2700

gactacaagg gcatggctca caaaaggtta atggatgggg gttacctagc cctggctaat   2760

tccccttcca ttcccaactc tctctctctt tttaaagaaa aatgctaagg gcagccctgc   2820

ctgccctccc catcccccgc tgtaaatata cactattttt gatagcacac atggggcccc   2880

catatctctt ggccttggtt ttgatgttga aatcctggcc ttgggagaga tgccttccag   2940

gcagacacag ctgtctggtt caggccaagc ccctttgcaa tgcaagccct ttctggtgtt   3000

atgaagtccc tctatgtcgt cgttttcacc agcaactggt gactgtccct tcgacacgga   3060

cctgctttga gatttcctga cagggaaaag atttctgtcc atttttttcc tgtgcctaac   3120

agcataattg ccttttccta tgtaaatatt atgatggtgg atcaagacat aagtaaatga   3180

gcctttctgc ctcacatcag ccctgtgtat aaagccatta ttctctgatg cactgtttgc   3240

cccagtaact cactttaaaa cctctctttc cagtgttccc tctctccctc cagggccact   3300

gcttgaagaa gaatatgtat gtttctatct tgtatgtctg tgtgcccctc ctgccccgaa   3360

agtgctgact atggggaaat cttttagctg ctgtttttag actccaagga gtggaaatta   3420

tgtggaagaa gcaaacctga tacaatttgc ccaaggtaaa cagtttgaaa agacaaatgg   3480

gcctgccaaa ctgtacagtt tcttccccaa gagctgttag gtatcaaaat gttgtccttt   3540

cccccctccg tgcttttctg gttgagatca tgtcattgat gaactgccaa agtcagggga   3600

ggagggcaga gactttgtgt ttacatctgc atttctacat gttttagaca gagacaattt   3660

aaggcctgca ctcttatttc actaaagaaa aactaatgtc agcacatgtt gctaatgaca   3720

gtggattttt ttttaaataa aaaagtttac agatcaaatg tgaaataaat atgaatggag   3780

tggtc                                                               3785


<210>  7414
<211>  465
<212>  PRT
<213>  Homo sapiens

<400>  7414

Met Phe Arg Gln Glu Gln Pro Leu Ala Glu Gly Ser Phe Ala Pro Met 
1               5                   10                  15


Gly Ser Leu Gln Pro Asp Ala Gly Asn Ala Ser Trp Asn Gly Thr Glu 
            20                  25                  30


Ala Pro Gly Gly Gly Ala Arg Ala Thr Pro Tyr Ser Leu Gln Val Thr 
        35                  40                  45


Leu Thr Leu Val Cys Leu Ala Gly Leu Leu Met Leu Leu Thr Val Phe 
    50                  55                  60


Gly Asn Val Leu Val Ile Ile Ala Val Phe Thr Ser Arg Ala Leu Lys 
65                  70                  75                  80


Ala Pro Gln Asn Leu Phe Leu Val Ser Leu Ala Ser Ala Asp Ile Leu 
                85                  90                  95


Val Ala Thr Leu Val Ile Pro Phe Ser Leu Ala Asn Glu Val Met Gly 
            100                 105                 110


Tyr Trp Tyr Phe Gly Lys Ala Trp Cys Glu Ile Tyr Leu Ala Leu Asp 
        115                 120                 125


Val Leu Phe Cys Thr Ser Ser Ile Val His Leu Cys Ala Ile Ser Leu 
    130                 135                 140


Asp Arg Tyr Trp Ser Ile Thr Gln Ala Ile Glu Tyr Asn Leu Lys Arg 
145                 150                 155                 160


Thr Pro Arg Arg Ile Lys Ala Ile Ile Ile Thr Val Trp Val Ile Ser 
                165                 170                 175


Ala Val Ile Ser Phe Pro Pro Leu Ile Ser Ile Glu Lys Lys Gly Gly 
            180                 185                 190


Gly Gly Gly Pro Gln Pro Ala Glu Pro Arg Cys Glu Ile Asn Asp Gln 
        195                 200                 205


Lys Trp Tyr Val Ile Ser Ser Cys Ile Gly Ser Phe Phe Ala Pro Cys 
    210                 215                 220


Leu Ile Met Ile Leu Val Tyr Val Arg Ile Tyr Gln Ile Ala Lys Arg 
225                 230                 235                 240


Arg Thr Arg Val Pro Pro Ser Arg Arg Gly Pro Asp Ala Val Ala Ala 
                245                 250                 255


Pro Pro Gly Gly Thr Glu Arg Arg Pro Asn Gly Leu Gly Pro Glu Arg 
            260                 265                 270


Ser Ala Gly Pro Gly Gly Ala Glu Ala Glu Pro Leu Pro Thr Gln Leu 
        275                 280                 285


Asn Gly Ala Pro Gly Glu Pro Ala Pro Ala Gly Pro Arg Asp Thr Asp 
    290                 295                 300


Ala Leu Asp Leu Glu Glu Ser Ser Ser Ser Asp His Ala Glu Arg Pro 
305                 310                 315                 320


Pro Gly Pro Arg Arg Pro Glu Arg Gly Pro Arg Gly Lys Gly Lys Ala 
                325                 330                 335


Arg Ala Ser Gln Val Lys Pro Gly Asp Ser Leu Pro Arg Arg Gly Pro 
            340                 345                 350


Gly Ala Thr Gly Ile Gly Thr Pro Ala Ala Gly Pro Gly Glu Glu Arg 
        355                 360                 365


Val Gly Ala Ala Lys Ala Ser Arg Trp Arg Gly Arg Gln Asn Arg Glu 
    370                 375                 380


Lys Arg Phe Thr Phe Val Leu Ala Val Val Ile Gly Val Phe Val Val 
385                 390                 395                 400


Cys Trp Phe Pro Phe Phe Phe Thr Tyr Thr Leu Thr Ala Val Gly Cys 
                405                 410                 415


Ser Val Pro Arg Thr Leu Phe Lys Phe Phe Phe Trp Phe Gly Tyr Cys 
            420                 425                 430


Asn Ser Ser Leu Asn Pro Val Ile Tyr Thr Ile Phe Asn His Asp Phe 
        435                 440                 445


Arg Arg Ala Phe Lys Lys Ile Leu Cys Arg Gly Asp Arg Lys Arg Ile 
    450                 455                 460


Val 
465


<210>  7415
<211>  3875
<212>  DNA
<213>  Homo sapiens

<400>  7415
ggagcagcag cagctccagc tcggtgcaga agcccagcag ccggcgtgcc gccgcccggc     60

cactccagcg ccttcttccc cgccttgcgc tcctgcccca actcgcgctg tcgtcggacc    120

ccggcccatc cagcagcgct cggcgcccac caggcggacg cccaggagaa cccctgcctc    180

cgtcgcggct cctggagagc tgatcgttca cctgccccgg cccgcctgag gacgggggtg    240

ccttcatgcg gcccccacac tcctcacccc gccgccgccg ccgtcccgga gctccgcaca    300

gtgtgcccca gccccagcag ggcgcacaac tttggaagtc tcgcggcgct ccgagaggcg    360

gcagagtccg cgccccagcc ccgggccggg ccgggccaga accgcagcgt ctgggggaag    420

ccagagagtc ggtaatcgct tcggggatgt aaggcgacag acataggacc cccgagctcg    480

catcagcacc cttcggctgc ctcccggggt gggggcgggc cccgcacacg gtaagacctc    540

ttgctttcgc tcaggctcaa gattcaagat acagatattg atatgtatat atatatttaa    600

tttcctgtca tccttccaag ttatcaggcc accgatgatt tttgttctcc cttcttgaag    660

aataaatctc tctttaccca tcggctctcc ctactctctc ccgccgctta gaaataaaac    720

ttggctgtat taggagctcg gagcaagaag gcgcccaccg agagcgtctg aagcgcgagc    780

caggcgcagt tcgcgggacc cgggccatgg gccgctagcg gtcctccagt tcgggcccgg    840

cctccctgcg gccccctccc tatgtgagcc gcagccaggc gagcggggcg ccggaggaag    900

aggaggaccc acgggcgccg ggccggaagg cagctggcag caggcccagg ccagcgggcg    960

cccgcgttca tgttccgcca ggagcagccg ttggccgagg gcagctttgc gcccatgggc   1020

tccctgcagc cggacgcggg caacgcgagc tggaacggga ccgaggcgcc ggggggcggc   1080

gcccgggcca ccccttactc cctgcaggtg acgctgacgc tggtgtgcct ggccggcctg   1140

ctcatgctgc tcaccgtgtt cggcaacgtg ctcgtcatca tcgccgtgtt cacgagccgc   1200

gcgctcaagg cgccccaaaa cctcttcctg gtgtctctgg cctcggccga catcctggtg   1260

gccacgctcg tcatcccttt ctcgctggcc aacgaggtca tgggctactg gtacttcggc   1320

aaggcttggt gcgagatcta cctggcgctc gacgtgctct tctgcacgtc gtccatcgtg   1380

cacctgtgcg ccatcagcct ggaccgctac tggtccatca cacaggccat cgagtacaac   1440

ctgaagcgca cgccgcgccg catcaaggcc atcatcatca ccgtgtgggt catctcggcc   1500

gtcatctcct tcccgccgct catctccatc gagaagaagg gcggcggcgg cggcccgcag   1560

ccggccgagc cgcgctgcga gatcaacgac cagaagtggt acgtcatctc gtcgtgcatc   1620

ggctccttct tcgctccctg cctcatcatg atcctggtct acgtgcgcat ctaccagatc   1680

gccaagcgtc gcacccgcgt gccacccagc cgccggggtc cggacgccgt cgccgcgccg   1740

ccggggggca ccgagcgcag gcccaacggt ctgggccccg agcgcagcgc gggcccgggg   1800

ggcgcagagg ccgaaccgct gcccacccag ctcaacggcg cccctggcga gcccgcgccg   1860

gccgggccgc gcgacaccga cgcgctggac ctggaggaga gctcgtcttc cgaccacgcc   1920

gagcggcctc cagggccccg cagacccgag cgcggtcccc ggggcaaagg caaggcccga   1980

gcgagccagg tgaagccggg cgacagcctg ccgcggcgcg ggccgggggc gacggggatc   2040

gggacgccgg ctgcagggcc gggggaggag cgcgtcgggg ctgccaaggc gtcgcgctgg   2100

cgcgggcggc agaaccgcga gaagcgcttc acgttcgtgc tggccgtggt catcggagtg   2160

ttcgtggtgt gctggttccc cttcttcttc acctacacgc tcacggccgt cgggtgctcc   2220

gtgccacgca cgctcttcaa attcttcttc tggttcggct actgcaacag ctcgttgaac   2280

ccggtcatct acaccatctt caaccacgat ttccgccgcg ccttcaagaa gatcctctgt   2340

cggggggaca ggaagcggat cgtgtgaggt ttccgctggc gcccgcgtag actcacgctg   2400

actgcaggca gcggggggca tcgaggggtg cttagcccca gggcactcag aaacccgggc   2460

gctgcctgct ctgcgtttcc tcgtctgggg tggctctgca gcctcctgcg ggcgggcgtc   2520

tgctgctcct acaagggaag cttcttgctg ccaggcccac acatccccag ttgttggttt   2580

ggccactctt gacctggagc catcttccta gtgggccacc cctaatcact attgcttcct   2640

aaaggtattt tcaccctctt cgcctggtac agccctcaca gctcttcaga gcaagcactg   2700

gactacaagg gcatggctca caaaaggtta atggatgggg gttacctagc cctggctaat   2760

tccccttcca ttcccaactc tctctctctt tttaaagaaa aatgctaagg gcagccctgc   2820

ctgccctccc catcccccgc tgtaaatata cactattttt gatagcacac atggggcccc   2880

catatctctt ggccttggtt ttgatgttga aatcctggcc ttgggagaga tgccttccag   2940

gcagacacag ctgtctggtt caggccaagc ccctttgcaa tgcaagccct ttctggtgtt   3000

atgaagtccc tctatgtcgt cgttttcacc agcaactggt gactgtccct tcgacacgga   3060

cctgctttga gatttcctga cagggaaaag atttctgtcc atttttttcc tgtgcctaac   3120

agcataattg ccttttccta tgtaaatatt atgatggtgg atcaagacat aagtaaatga   3180

gcctttctgc ctcacatcag ccctgtgtat aaagccatta ttctctgatg cactgtttgc   3240

cccagtaact cactttaaaa cctctctttc cagtgttccc tctctccctc cagggccact   3300

gcttgaagaa gaatatgtat gtttctatct tgtatgtctg tgtgcccctc ctgccccgaa   3360

agtgctgact atggggaaat cttttagctg ctgtttttag actccaagga gtggaaatta   3420

tgtggaagaa gcaaacctga tacaatttgc ccaaggtaaa cagtttgaaa agacaaatgg   3480

gcctgccaaa ctgtacagtt tcttccccaa gagctgttag gtatcaaaat gttgtccttt   3540

cccccctccg tgcttttctg gttgagatca tgtcattgat gaactgccaa agtcagggga   3600

ggagggcaga gactttgtgt ttacatctgc atttctacat gttttagaca gagacaattt   3660

aaggcctgca ctcttatttc actaaagaaa aactaatgtc agcacatgtt gctaatgaca   3720

gtggattttt ttttaaataa aaaagtttac agatcaaatg tgaaataaat atgaatggag   3780

tggtcctctt gtctgttatc tgagttttca aaagctttaa gactctggga acatctgatt   3840

ttatggattt tttaaaaata aaaaatgtac attat                              3875


<210>  7416
<211>  465
<212>  PRT
<213>  Homo sapiens

<400>  7416

Met Phe Arg Gln Glu Gln Pro Leu Ala Glu Gly Ser Phe Ala Pro Met 
1               5                   10                  15


Gly Ser Leu Gln Pro Asp Ala Gly Asn Ala Ser Trp Asn Gly Thr Glu 
            20                  25                  30


Ala Pro Gly Gly Gly Ala Arg Ala Thr Pro Tyr Ser Leu Gln Val Thr 
        35                  40                  45


Leu Thr Leu Val Cys Leu Ala Gly Leu Leu Met Leu Leu Thr Val Phe 
    50                  55                  60


Gly Asn Val Leu Val Ile Ile Ala Val Phe Thr Ser Arg Ala Leu Lys 
65                  70                  75                  80


Ala Pro Gln Asn Leu Phe Leu Val Ser Leu Ala Ser Ala Asp Ile Leu 
                85                  90                  95


Val Ala Thr Leu Val Ile Pro Phe Ser Leu Ala Asn Glu Val Met Gly 
            100                 105                 110


Tyr Trp Tyr Phe Gly Lys Ala Trp Cys Glu Ile Tyr Leu Ala Leu Asp 
        115                 120                 125


Val Leu Phe Cys Thr Ser Ser Ile Val His Leu Cys Ala Ile Ser Leu 
    130                 135                 140


Asp Arg Tyr Trp Ser Ile Thr Gln Ala Ile Glu Tyr Asn Leu Lys Arg 
145                 150                 155                 160


Thr Pro Arg Arg Ile Lys Ala Ile Ile Ile Thr Val Trp Val Ile Ser 
                165                 170                 175


Ala Val Ile Ser Phe Pro Pro Leu Ile Ser Ile Glu Lys Lys Gly Gly 
            180                 185                 190


Gly Gly Gly Pro Gln Pro Ala Glu Pro Arg Cys Glu Ile Asn Asp Gln 
        195                 200                 205


Lys Trp Tyr Val Ile Ser Ser Cys Ile Gly Ser Phe Phe Ala Pro Cys 
    210                 215                 220


Leu Ile Met Ile Leu Val Tyr Val Arg Ile Tyr Gln Ile Ala Lys Arg 
225                 230                 235                 240


Arg Thr Arg Val Pro Pro Ser Arg Arg Gly Pro Asp Ala Val Ala Ala 
                245                 250                 255


Pro Pro Gly Gly Thr Glu Arg Arg Pro Asn Gly Leu Gly Pro Glu Arg 
            260                 265                 270


Ser Ala Gly Pro Gly Gly Ala Glu Ala Glu Pro Leu Pro Thr Gln Leu 
        275                 280                 285


Asn Gly Ala Pro Gly Glu Pro Ala Pro Ala Gly Pro Arg Asp Thr Asp 
    290                 295                 300


Ala Leu Asp Leu Glu Glu Ser Ser Ser Ser Asp His Ala Glu Arg Pro 
305                 310                 315                 320


Pro Gly Pro Arg Arg Pro Glu Arg Gly Pro Arg Gly Lys Gly Lys Ala 
                325                 330                 335


Arg Ala Ser Gln Val Lys Pro Gly Asp Ser Leu Pro Arg Arg Gly Pro 
            340                 345                 350


Gly Ala Thr Gly Ile Gly Thr Pro Ala Ala Gly Pro Gly Glu Glu Arg 
        355                 360                 365


Val Gly Ala Ala Lys Ala Ser Arg Trp Arg Gly Arg Gln Asn Arg Glu 
    370                 375                 380


Lys Arg Phe Thr Phe Val Leu Ala Val Val Ile Gly Val Phe Val Val 
385                 390                 395                 400


Cys Trp Phe Pro Phe Phe Phe Thr Tyr Thr Leu Thr Ala Val Gly Cys 
                405                 410                 415


Ser Val Pro Arg Thr Leu Phe Lys Phe Phe Phe Trp Phe Gly Tyr Cys 
            420                 425                 430


Asn Ser Ser Leu Asn Pro Val Ile Tyr Thr Ile Phe Asn His Asp Phe 
        435                 440                 445


Arg Arg Ala Phe Lys Lys Ile Leu Cys Arg Gly Asp Arg Lys Arg Ile 
    450                 455                 460


Val 
465


<210>  7417
<211>  2163
<212>  DNA
<213>  Homo sapiens

<400>  7417
atgagtctta aatgtctgcc tcatgggctt ctcgtgcgaa ccggggagct gtttttaaag     60

ccagtggagt ggaatgtcct ttcactaagc cgttctgcaa aggtccagtg tggttctcta    120

aggacttcgc tgccgtcgag acgcgcagcg gatgccgctg cttgccgcgg cggaggaagc    180

tacgccgctg cgccttcggt tcaccttgcc cccattaaag cgttagttag acagctccaa    240

acgccagctg gccggagaga cttcctggga gaaagtgctg tcgtcggggt cacagactcg    300

gagttgatcc gcgagccttg ggcaccggcg gccagagcag aggggtgccc ttccgagagc    360

agccgtcggt gccgagaagc tgttgcccca gcagccccac cgagtgacgc gcgggttttg    420

gccgggtcag cgcgcatacg cacacaggca cacccactcc tggtcccggg ggaaggctca    480

ctcttcggtt ttccagggct aaaggccaag gccacgcgga tttctgagtc cgaagacgca    540

gtgcgaggac ttacacctgg attcccttac tatcggctgg atggcctggc ggcgggaagc    600

gggtccctgc gccgcagggg ggagaggcag gcgcggtctc cgggctcgcg gccgttagtg    660

cgcttcggcc aagggcgccg cctgctccgc gtccctcgct cgcctcctgc gctcgcagga    720

gcgctccgac ccgaagccaa agcgccaaaa tccgagggaa gcatccggcg ccggattgac    780

gcagcctcga gccggggact gctcttgctg cctcctccgc gggagccgca gccgcagccg    840

agccgcctcg atccctcggt gccgcggcag ggccgctccc cgcccctccg cacccctccc    900

tcatgcgagc ccgcccgtct gggtcctcac tccgccctcc cgccgttgga tttgcgcccg    960

gggcggcccc cgactttgcg ccccgtagtt gagttccgtt tatggtctga tttccggcct   1020

ctcgcctgct cgccccgccg cccgcctgtc ccgctccctc cctcccgggg acccggagga   1080

gaggggacca tgccggaacc cgggccggac gctgccggca ccgccagcgc acagccccaa   1140

ccgccgccgc cccccccacc cgctcccaag gagtccccgt tctccatcaa gaacctgctc   1200

aacggagacc accaccggcc gccccctaag cctcagccgc ccccacggac gctcttcgcg   1260

ccagcctcgg ctgccgccgc cgccgccgct gccgctgccg cggcggccaa gggggccctg   1320

gagggcgccg cgggcttcgc gctctcgcag gtgggcgacc tggctttccc tcgctttgag   1380

atcccggcgc agaggtttgc cctgcccgcg cactacctgg agcgctcccc agcctggtgg   1440

tacccctaca ccctgacccc cgccggcggc cacctcccgc gacctgaagc ctcggagaag   1500

gccttgctga gagactcctc ccccgcctcc ggcacagacc gcgactctcc ggagccactg   1560

ctcaaggccg accccgatca caaggagctg gactccaaga gcccggacga gatcattctg   1620

gaggagagcg actccgagga aagcaaaaag gaaggcgaag cggcgccagg cgcggccggg   1680

gcgagcgtag gggcggcggc ggccactccg ggcgcagaag actggaagaa gggcgctgaa   1740

agtccagaga agaagccggc gtgccgcaag aagaagacgc gcacagtctt ctcgcgcagc   1800

caggtcttcc agctcgagtc caccttcgac atgaagcgct atctgagcag ctcggagcga   1860

gccggcctgg ccgcgtccct gcacctcacc gagacgcagg tcaagatctg gttccagaac   1920

cgccgcaaca agtggaagcg gcagctggcg gcggagctgg aggcggccaa cctgagccat   1980

gccgcggcgc agcgcatcgt gcgggtgccc atcctctacc acgagaactc ggcggccgag   2040

ggcgcggcgg ctgcagccgc gggggccccg gtgccagtca gccagccgct gctcaccttc   2100

ccgcaccccg tctactactc gcacccggtg gtctcttccg tgccgctgct acggccggtc   2160

tga                                                                 2163


<210>  7418
<211>  720
<212>  PRT
<213>  Homo sapiens

<400>  7418

Met Ser Leu Lys Cys Leu Pro His Gly Leu Leu Val Arg Thr Gly Glu 
1               5                   10                  15


Leu Phe Leu Lys Pro Val Glu Trp Asn Val Leu Ser Leu Ser Arg Ser 
            20                  25                  30


Ala Lys Val Gln Cys Gly Ser Leu Arg Thr Ser Leu Pro Ser Arg Arg 
        35                  40                  45


Ala Ala Asp Ala Ala Ala Cys Arg Gly Gly Gly Ser Tyr Ala Ala Ala 
    50                  55                  60


Pro Ser Val His Leu Ala Pro Ile Lys Ala Leu Val Arg Gln Leu Gln 
65                  70                  75                  80


Thr Pro Ala Gly Arg Arg Asp Phe Leu Gly Glu Ser Ala Val Val Gly 
                85                  90                  95


Val Thr Asp Ser Glu Leu Ile Arg Glu Pro Trp Ala Pro Ala Ala Arg 
            100                 105                 110


Ala Glu Gly Cys Pro Ser Glu Ser Ser Arg Arg Cys Arg Glu Ala Val 
        115                 120                 125


Ala Pro Ala Ala Pro Pro Ser Asp Ala Arg Val Leu Ala Gly Ser Ala 
    130                 135                 140


Arg Ile Arg Thr Gln Ala His Pro Leu Leu Val Pro Gly Glu Gly Ser 
145                 150                 155                 160


Leu Phe Gly Phe Pro Gly Leu Lys Ala Lys Ala Thr Arg Ile Ser Glu 
                165                 170                 175


Ser Glu Asp Ala Val Arg Gly Leu Thr Pro Gly Phe Pro Tyr Tyr Arg 
            180                 185                 190


Leu Asp Gly Leu Ala Ala Gly Ser Gly Ser Leu Arg Arg Arg Gly Glu 
        195                 200                 205


Arg Gln Ala Arg Ser Pro Gly Ser Arg Pro Leu Val Arg Phe Gly Gln 
    210                 215                 220


Gly Arg Arg Leu Leu Arg Val Pro Arg Ser Pro Pro Ala Leu Ala Gly 
225                 230                 235                 240


Ala Leu Arg Pro Glu Ala Lys Ala Pro Lys Ser Glu Gly Ser Ile Arg 
                245                 250                 255


Arg Arg Ile Asp Ala Ala Ser Ser Arg Gly Leu Leu Leu Leu Pro Pro 
            260                 265                 270


Pro Arg Glu Pro Gln Pro Gln Pro Ser Arg Leu Asp Pro Ser Val Pro 
        275                 280                 285


Arg Gln Gly Arg Ser Pro Pro Leu Arg Thr Pro Pro Ser Cys Glu Pro 
    290                 295                 300


Ala Arg Leu Gly Pro His Ser Ala Leu Pro Pro Leu Asp Leu Arg Pro 
305                 310                 315                 320


Gly Arg Pro Pro Thr Leu Arg Pro Val Val Glu Phe Arg Leu Trp Ser 
                325                 330                 335


Asp Phe Arg Pro Leu Ala Cys Ser Pro Arg Arg Pro Pro Val Pro Leu 
            340                 345                 350


Pro Pro Ser Arg Gly Pro Gly Gly Glu Gly Thr Met Pro Glu Pro Gly 
        355                 360                 365


Pro Asp Ala Ala Gly Thr Ala Ser Ala Gln Pro Gln Pro Pro Pro Pro 
    370                 375                 380


Pro Pro Pro Ala Pro Lys Glu Ser Pro Phe Ser Ile Lys Asn Leu Leu 
385                 390                 395                 400


Asn Gly Asp His His Arg Pro Pro Pro Lys Pro Gln Pro Pro Pro Arg 
                405                 410                 415


Thr Leu Phe Ala Pro Ala Ser Ala Ala Ala Ala Ala Ala Ala Ala Ala 
            420                 425                 430


Ala Ala Ala Ala Lys Gly Ala Leu Glu Gly Ala Ala Gly Phe Ala Leu 
        435                 440                 445


Ser Gln Val Gly Asp Leu Ala Phe Pro Arg Phe Glu Ile Pro Ala Gln 
    450                 455                 460


Arg Phe Ala Leu Pro Ala His Tyr Leu Glu Arg Ser Pro Ala Trp Trp 
465                 470                 475                 480


Tyr Pro Tyr Thr Leu Thr Pro Ala Gly Gly His Leu Pro Arg Pro Glu 
                485                 490                 495


Ala Ser Glu Lys Ala Leu Leu Arg Asp Ser Ser Pro Ala Ser Gly Thr 
            500                 505                 510


Asp Arg Asp Ser Pro Glu Pro Leu Leu Lys Ala Asp Pro Asp His Lys 
        515                 520                 525


Glu Leu Asp Ser Lys Ser Pro Asp Glu Ile Ile Leu Glu Glu Ser Asp 
    530                 535                 540


Ser Glu Glu Ser Lys Lys Glu Gly Glu Ala Ala Pro Gly Ala Ala Gly 
545                 550                 555                 560


Ala Ser Val Gly Ala Ala Ala Ala Thr Pro Gly Ala Glu Asp Trp Lys 
                565                 570                 575


Lys Gly Ala Glu Ser Pro Glu Lys Lys Pro Ala Cys Arg Lys Lys Lys 
            580                 585                 590


Thr Arg Thr Val Phe Ser Arg Ser Gln Val Phe Gln Leu Glu Ser Thr 
        595                 600                 605


Phe Asp Met Lys Arg Tyr Leu Ser Ser Ser Glu Arg Ala Gly Leu Ala 
    610                 615                 620


Ala Ser Leu His Leu Thr Glu Thr Gln Val Lys Ile Trp Phe Gln Asn 
625                 630                 635                 640


Arg Arg Asn Lys Trp Lys Arg Gln Leu Ala Ala Glu Leu Glu Ala Ala 
                645                 650                 655


Asn Leu Ser His Ala Ala Ala Gln Arg Ile Val Arg Val Pro Ile Leu 
            660                 665                 670


Tyr His Glu Asn Ser Ala Ala Glu Gly Ala Ala Ala Ala Ala Ala Gly 
        675                 680                 685


Ala Pro Val Pro Val Ser Gln Pro Leu Leu Thr Phe Pro His Pro Val 
    690                 695                 700


Tyr Tyr Ser His Pro Val Val Ser Ser Val Pro Leu Leu Arg Pro Val 
705                 710                 715                 720


<210>  7419
<211>  1628
<212>  DNA
<213>  Homo sapiens

<400>  7419
cgggcgagga aggggcattt gcaccggggc tgggcgggcg cacccagagc caggcgggca     60

ggaacccctg cgcagccatc cggtgcctgc atgtccctgg cgcggaaggg acgcctcacc    120

agcctcggcg ccccctcccc ctagatttcc tccccgcccc tccccactgc ctgcctgctg    180

caccaccttc cacccagatc acccagatcg tctctaaagg gagttcttgg tttccttcga    240

tttcttatga acccaggatg ggcagcaaag aagatgcggg caaggggtgt ccggcggccg    300

gtggcgtctc cagcttcacc atccagtcca tcctgggcgg gggcccctcg gaggcaccgc    360

gggagcccgt cggctggcca gccaggaagc gcagcctgtc cgtgtcctcg gaggaggagg    420

agccggacga cggctggaag gcgcccgcct gcttctgccc agaccagcac ggccctaagg    480

agcagggccc caagcaccat ccccccatcc cttttccttg cctgggtacc cccaagggca    540

gcggaggctc gggcccgggc ggcttggagc gcacgccttt cctctctcct tcgcactcgg    600

actttaaaga agagaaagag aggctcctgc ccgcgggctc gccctcgccg gggtccgagc    660

ggccgcggga cggcggcgct gagcggcagg ccggcgcggc caagaagaag acgcgcaccg    720

tcttttcgcg cagccaggtg taccagctcg agtccacctt cgacatgaag cgctacctga    780

gcagctcgga gcgcgcctgc ctcgcctcca gcctgcagct cacggagacc caggtaaaga    840

cttggttcca gaaccgccgc aacaagtgga agcggcagct ctcggctgag ctggaggcgg    900

ccaacatggc gcacgcgtcg gcgcagactc tggtgagcat gccgctggtg ttccgggaca    960

gttcgctgct gcgcgtgccg gtgccgcgct cgctcgcctt tcccgcgccg ctctactacc   1020

cgggaagcaa cctctcggcc ttacctctct acaacctata caacaagctc gactactgac   1080

cggcccgccg ccccgcgccg cccccagctg cccgcagagc cgggcgcgta ctgtactgta   1140

agcagggctc cggagcaagg cggcgtgttt ccagaaatat gaagaaatac accatgtgta   1200

ttcattagct cttatttatg gtctctgccc tactttttgt tttgattgtt tcgggtattt   1260

attggcattc cctaagtcag agagcctgct tcctacctag accgaaccag tacgctttga   1320

aaaccattcg gagtgagatg ttctcgggtg gtggtgggaa agggagtttt ggccagacag   1380

gctgtggttg gtagggaaaa aaatcaggaa aacacctaca aaaccaggta cactcctccc   1440

ccatatatac acctgtatat atgtacatgc atacacgctc ggccaagcca ggccctcaga   1500

ggctttggac aattactaaa ttgcttcttt tcgtttccct catcccgagg atggtaggga   1560

cgaaaagggg agagttcaga tctgtaaata tttttaaaaa gaaaaaaaaa taaaacattt   1620

taaacatc                                                            1628


<210>  7420
<211>  273
<212>  PRT
<213>  Homo sapiens

<400>  7420

Met Gly Ser Lys Glu Asp Ala Gly Lys Gly Cys Pro Ala Ala Gly Gly 
1               5                   10                  15


Val Ser Ser Phe Thr Ile Gln Ser Ile Leu Gly Gly Gly Pro Ser Glu 
            20                  25                  30


Ala Pro Arg Glu Pro Val Gly Trp Pro Ala Arg Lys Arg Ser Leu Ser 
        35                  40                  45


Val Ser Ser Glu Glu Glu Glu Pro Asp Asp Gly Trp Lys Ala Pro Ala 
    50                  55                  60


Cys Phe Cys Pro Asp Gln His Gly Pro Lys Glu Gln Gly Pro Lys His 
65                  70                  75                  80


His Pro Pro Ile Pro Phe Pro Cys Leu Gly Thr Pro Lys Gly Ser Gly 
                85                  90                  95


Gly Ser Gly Pro Gly Gly Leu Glu Arg Thr Pro Phe Leu Ser Pro Ser 
            100                 105                 110


His Ser Asp Phe Lys Glu Glu Lys Glu Arg Leu Leu Pro Ala Gly Ser 
        115                 120                 125


Pro Ser Pro Gly Ser Glu Arg Pro Arg Asp Gly Gly Ala Glu Arg Gln 
    130                 135                 140


Ala Gly Ala Ala Lys Lys Lys Thr Arg Thr Val Phe Ser Arg Ser Gln 
145                 150                 155                 160


Val Tyr Gln Leu Glu Ser Thr Phe Asp Met Lys Arg Tyr Leu Ser Ser 
                165                 170                 175


Ser Glu Arg Ala Cys Leu Ala Ser Ser Leu Gln Leu Thr Glu Thr Gln 
            180                 185                 190


Val Lys Thr Trp Phe Gln Asn Arg Arg Asn Lys Trp Lys Arg Gln Leu 
        195                 200                 205


Ser Ala Glu Leu Glu Ala Ala Asn Met Ala His Ala Ser Ala Gln Thr 
    210                 215                 220


Leu Val Ser Met Pro Leu Val Phe Arg Asp Ser Ser Leu Leu Arg Val 
225                 230                 235                 240


Pro Val Pro Arg Ser Leu Ala Phe Pro Ala Pro Leu Tyr Tyr Pro Gly 
                245                 250                 255


Ser Asn Leu Ser Ala Leu Pro Leu Tyr Asn Leu Tyr Asn Lys Leu Asp 
            260                 265                 270


Tyr 



<210>  7421
<211>  1208
<212>  DNA
<213>  Homo sapiens

<400>  7421
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

ccgcagagtg ttggtgtggg acttacggaa catgggttac gtgcagcagc gcagggagtc    720

cagcctgaaa taccagactc gctgcatacg agcgtttcca aacaagcagg tattgaacta    780

tacctcctct tctttctgga atttgaaaat aatatgatct tatattataa tgatttggcc    840

actagcccct aaagccttct tttttttttt cagtagtgat ttagaatttg ctgttaggtg    900

tattcttcct tgatattttt gacagccatg tgttaacagg aagtgcgtta acccccattt    960

tagagacgac cttgatgttc agagagacca agtaatctgc tcaggaagtg gtttgaatag   1020

aggaggtttt ctgacctttt gttgatcctg gtccaggatg cttcataggt atacagtaat   1080

caaagagcgc tttgcagata tttcagttta caaaatgctg aattaaaatt tatatctgga   1140

ttttaagctt atggaatttg ctgttttctt tttgcctttt tgtaacccta atgcttatgg   1200

agttcttt                                                            1208


<210>  7422
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  7422

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Ala Ala Glu Cys Trp 
    130                 135                 140


Cys Gly Thr Tyr Gly Thr Trp Val Thr Cys Ser Ser Ala Gly Ser Pro 
145                 150                 155                 160


Ala 



<210>  7423
<211>  1592
<212>  DNA
<213>  Homo sapiens

<400>  7423
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

tatataccct ctcagtgtct ggagaccggc tgattgtggg aacagcaggc cgcagagtgt    720

tggtgtggga cttacggaac atgggttacg tgcagcagcg cagggagtcc agcctgaaat    780

accagactcg ctgcatacga gcgtttccaa acaagcaggg ttatgtatta agctctattg    840

aaggccgagt ggcagttgag tatttggacc caagccctga ggtacagaag aagaagtatg    900

ccttcaaatg tcacagacta aaagaaaata atattgagca gatttaccca gtcaatgcca    960

tttcttttca caatatccac aatacatttg ccacaggtgg ttctgatggc tttgtaaata   1020

tttgggatcc atttaacaaa aagcgactgt gccaattcca tcggtacccc acgagcatcg   1080

catcacttgc cttcagtaat gatgggacta cgcttgcaat agcgtcatca tatatgtatg   1140

aaatggatga cacagaacat cctgaagatg gtatcttcat tcgccaagtg acagatgcag   1200

aaacaaaacc caagtcacca tgtacttgac aagatttcat ttacttaagt gccatgttga   1260

tgataataaa acaattcgta ctccccaatg gtggatttat tactattaaa gaaaccaggg   1320

aaaatattaa ttttaatatt ataacaacct gaaaataatg gaaaagaggt ttttgaattt   1380

ttttttttaa ataaacacct tcttaagtgc atgagatggt ttgatggttt gctgcattaa   1440

aggtatttgg gcaaacaaaa ttggagggca agtgactgca gttttgagaa tcagttttga   1500

ccttgatgat tttttgtttc cactgtggaa ataaatgttt gtaaataagt gtaataaaaa   1560

tccctttgca ttctttctgg accttaaatg gt                                 1592


<210>  7424
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  7424

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Val Tyr Thr Leu Ser 
    130                 135                 140


Val Ser Gly Asp Arg Leu Ile Val Gly Thr Ala Gly Arg Arg Val Leu 
145                 150                 155                 160


Val Trp Asp Leu Arg Asn Met Gly Tyr Val Gln Gln Arg Arg Glu Ser 
                165                 170                 175


Ser Leu Lys Tyr Gln Thr Arg Cys Ile Arg Ala Phe Pro Asn Lys Gln 
            180                 185                 190


Gly Tyr Val Leu Ser Ser Ile Glu Gly Arg Val Ala Val Glu Tyr Leu 
        195                 200                 205


Asp Pro Ser Pro Glu Val Gln Lys Lys Lys Tyr Ala Phe Lys Cys His 
    210                 215                 220


Arg Leu Lys Glu Asn Asn Ile Glu Gln Ile Tyr Pro Val Asn Ala Ile 
225                 230                 235                 240


Ser Phe His Asn Ile His Asn Thr Phe Ala Thr Gly Gly Ser Asp Gly 
                245                 250                 255


Phe Val Asn Ile Trp Asp Pro Phe Asn Lys Lys Arg Leu Cys Gln Phe 
            260                 265                 270


His Arg Tyr Pro Thr Ser Ile Ala Ser Leu Ala Phe Ser Asn Asp Gly 
        275                 280                 285


Thr Thr Leu Ala Ile Ala Ser Ser Tyr Met Tyr Glu Met Asp Asp Thr 
    290                 295                 300


Glu His Pro Glu Asp Gly Ile Phe Ile Arg Gln Val Thr Asp Ala Glu 
305                 310                 315                 320


Thr Lys Pro Lys Ser Pro Cys Thr 
                325


<210>  7425
<211>  1532
<212>  DNA
<213>  Homo sapiens

<400>  7425
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

tatataccct ctcagtgtct ggagaccggc tgattgtggg aacagcaggc cgcagagtgt    720

tggtgtggga cttacggaac atgggttacg tgcagcagcg cagggagtcc agcctgaaat    780

accagactcg ctgcatacga gcgtttccaa acaagcaggg ttatgtatta agctctattg    840

aaggccgagt ggcagttgag tatttggacc caagccctga ggtacagaag aagaagtatg    900

ccttcaaatg tcacagacta aaagaaaata atattgagca gatttaccca gtcaatgcca    960

tttcttttca caatatccac aatacatttg ccacaggtgg ttctgatggc tttgtaaata   1020

tttgggatcc atttaacaaa aagcgactgt gccaattcca tcggtacccc acgagcatcg   1080

catcacttgc cttcagtaat gatgggacta cgcttgcaat agcgtcatca tatatgtatg   1140

aaatggatga cacagaacat cctgaagatg gtatcttcat tcgccaagtg acagatgcag   1200

aaacaaaacc caagtccacc taatcatcct gtgaaagtgg tttctctatg gaaagctttg   1260

tttgcttcct acaaatacat gcttattcct taagggatgt gttagagtta ctgtggattt   1320

ctctgttttc tgtcttacaa gaaacttgtc tatgtacctt aatactttgt ttaggatgag   1380

gagtctttgt gtccctgtac agtagtctga cgtatttccc cttctgtccc ctagtaagcc   1440

cagttgctgt atctgaacag tttgagctct ttttgtaata tactctaaac ctgttatttc   1500

tgtgctaata aacgagatgc agaacccttg aa                                 1532


<210>  7426
<211>  326
<212>  PRT
<213>  Homo sapiens

<400>  7426

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Val Tyr Thr Leu Ser 
    130                 135                 140


Val Ser Gly Asp Arg Leu Ile Val Gly Thr Ala Gly Arg Arg Val Leu 
145                 150                 155                 160


Val Trp Asp Leu Arg Asn Met Gly Tyr Val Gln Gln Arg Arg Glu Ser 
                165                 170                 175


Ser Leu Lys Tyr Gln Thr Arg Cys Ile Arg Ala Phe Pro Asn Lys Gln 
            180                 185                 190


Gly Tyr Val Leu Ser Ser Ile Glu Gly Arg Val Ala Val Glu Tyr Leu 
        195                 200                 205


Asp Pro Ser Pro Glu Val Gln Lys Lys Lys Tyr Ala Phe Lys Cys His 
    210                 215                 220


Arg Leu Lys Glu Asn Asn Ile Glu Gln Ile Tyr Pro Val Asn Ala Ile 
225                 230                 235                 240


Ser Phe His Asn Ile His Asn Thr Phe Ala Thr Gly Gly Ser Asp Gly 
                245                 250                 255


Phe Val Asn Ile Trp Asp Pro Phe Asn Lys Lys Arg Leu Cys Gln Phe 
            260                 265                 270


His Arg Tyr Pro Thr Ser Ile Ala Ser Leu Ala Phe Ser Asn Asp Gly 
        275                 280                 285


Thr Thr Leu Ala Ile Ala Ser Ser Tyr Met Tyr Glu Met Asp Asp Thr 
    290                 295                 300


Glu His Pro Glu Asp Gly Ile Phe Ile Arg Gln Val Thr Asp Ala Glu 
305                 310                 315                 320


Thr Lys Pro Lys Ser Thr 
                325


<210>  7427
<211>  978
<212>  DNA
<213>  Homo sapiens

<400>  7427
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

tccacctaat catcctgtga aagtggtttc tctatggaaa gctttgtttg cttcctacaa    720

atacatgctt attccttaag ggatgtgtta gagttactgt ggatttctct gttttctgtc    780

ttacaagaaa cttgtctatg taccttaata ctttgtttag gatgaggagt ctttgtgtcc    840

ctgtacagta gtctgacgta tttccccttc tgtcccctag taagcccagt tgctgtatct    900

gaacagtttg agctcttttt gtaatatact ctaaacctgt tatttctgtg ctaataaacg    960

agatgcagaa cccttgaa                                                  978


<210>  7428
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  7428

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Val His Leu Ile Ile 
    130                 135                 140


Leu 
145


<210>  7429
<211>  3755
<212>  DNA
<213>  Homo sapiens

<400>  7429
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

tatataccct ctcagtgtct ggagaccggc tgattgtggg aacagcaggc cgcagagtgt    720

tggtgtggga cttacggaac atgggttacg tgcagcagcg cagggagtcc agcctgaaat    780

accagactcg ctgcatacga gcgtttccaa acaagcaggg ttatgtatta agctctattg    840

aaggccgagt ggcagttgag tatttggacc caagccctga ggtacagaag aagaagtatg    900

ccttcaaatg tcacagacta aaagaaaata atattgagca gatttaccca gtcaatgcca    960

tttcttttca caatatccac aatacatttg ccacaggtgg ttctgatggc tttgtaaata   1020

tttgggatcc atttaacaaa aagcgactgt gccaattcca tcggtacccc acgagcatcg   1080

catcacttgc cttcagtaat gatgggacta cgcttgcaat agcgtcatca tatatgtatg   1140

aaatggatga cacagaacat cctgaagatg gtatcttcat tcgccaagtg acagatgcag   1200

aaacaaaacc caagtgagta tgcttcacct gtatttgagc cttttcttgc attcaaccca   1260

ggatttatta atttttctaa attcatgaat agcattgttg atgcctgctc gatattacag   1320

ctgactgtag ggttggagtt gatgttatca tgttctccca agctttcaat atccgtaggt   1380

tgatagacgt ctgatggata aaattgtgcc tagttgtttt gtagagaaga atgtcaaact   1440

cttattcttc ttgaataggc tctattattt gaatctctgg agttattacc agctcattgc   1500

ttcaaaatta agttgaggaa ttcaagaata atttatttta gtaaattcta tttaagatgt   1560

ttaagaattt gaactgccaa aaatctttcc tctccacaga ggttgtttct ttaatattaa   1620

cacaaagtaa gtgaccttca ggtcttattg gaaactcaga gtaatatggc cttgcctgga   1680

attgcaaatt tccttagttt tgaaattttc atagatgtct ttggttcttg gttgtaactg   1740

ttgactgaga agagccattt acattttttg ataccaacag ggcaaagctt tttacttaat   1800

tacctctacc aggctttaag ggaaatctga tacttcagca tgtgttaaac tataaaatac   1860

ctactccaag tatctgccca gttccttgtc ccctctcccc aggcccttaa aggaagttct   1920

cgatacatat ttgtagaata actgaatgtt ttcaggattc ctgtactttg ctgagttaaa   1980

atggatatgg tacccttgct gattggttga gcccctaaga gggggcagaa tattaaatat   2040

tccatatcag atatgctttt acaggtttga ctttagaaaa gtcttagcat gtgaagcctg   2100

ttggataaag ggctgtgttt gcatttaatc tgtcactttt gtatctcctg tcctggctgg   2160

ccattttgat ctcatgctgt tctttttttc ttttgaactt gtaggtcacc atgtacttga   2220

caagatttca tttacttaag tgccatgttg atgataataa aacaattcgt actccccaat   2280

ggtggattta ttactattaa agaaaccagg gaaaatatta attttaatat tataacaacc   2340

tgaaaataat ggaaaagagg tttttgaatt ttttttttta aataaacacc ttcttaagtg   2400

catgagatgg tttgatggtt tgctgcatta aaggtatttg ggcaaacaaa attggagggc   2460

aagtgactgc agttttgaga atcagttttg accttgatga ttttttgttt ccactgtgga   2520

aataaatgtt tgtaaataag tgtaataaaa atccctttgc attctttctg gaccttaaat   2580

ggtagaggaa aaggctcgtg agccatttgt ttcttttgct ggttatagtt gctaattcta   2640

aagctgcttc agactgcttc atgaggaggt taatctacaa ttaaacaata tttcctcttg   2700

gccgtccatt attttctgaa gcagatggtt catcatttcc tgggctgtta aacaaagcga   2760

ggttaaggtt agactcttgg gaatcagcta gttttcaatc ttattagggt gcagaaggaa   2820

aactaataag aaaacctcct aatatcattt tgtgactgta aacaattatt tattagcaaa   2880

caattgatcc cagaagggca aattgtttga gtcagtaatg agctgagaaa agacagagca   2940

tatctgtgta tttggaaaaa taattgtaac gtaattgcag tgcatttaga caggcatcta   3000

tttggacctg tttctatctc taaatgaatt tttggaaaca ttaatgaggt ttacatattt   3060

ctctgacatt tatatagttc ttatgtccat ttcagttgac cagccgctgg tgattaaagt   3120

taaaaagaaa aaaattatag tgagaatgag attcatttca atgtaatgca ctaaagcaga   3180

acacgaactt agcttggcct attctaggta gttccaaata gtatttttgt tgtcaaactt   3240

taaaatttat attaatttgc aaatgtatgt ctctgagtag gacttggacc tttcctgaga   3300

tttattttat ccgtgatgta ttttttttaa ttcttttgat acagagaagg gtcttttttt   3360

ttttaagtat ttcagtgaaa acttggtgta agtctgaacc catcttttga aatgtatttt   3420

cttcattgca ggtccaccta atcatcctgt gaaagtggtt tctctatgga aagctttgtt   3480

tgcttcctac aaatacatgc ttattcctta agggatgtgt tagagttact gtggatttct   3540

ctgttttctg tcttacaaga aacttgtcta tgtaccttaa tactttgttt aggatgagga   3600

gtctttgtgt ccctgtacag tagtctgacg tatttcccct tctgtcccct agtaagccca   3660

gttgctgtat ctgaacagtt tgagctcttt ttgtaatata ctctaaacct gttatttctg   3720

tgctaataaa cgagatgcag aacccttgaa tgttg                              3755


<210>  7430
<211>  324
<212>  PRT
<213>  Homo sapiens

<400>  7430

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Val Tyr Thr Leu Ser 
    130                 135                 140


Val Ser Gly Asp Arg Leu Ile Val Gly Thr Ala Gly Arg Arg Val Leu 
145                 150                 155                 160


Val Trp Asp Leu Arg Asn Met Gly Tyr Val Gln Gln Arg Arg Glu Ser 
                165                 170                 175


Ser Leu Lys Tyr Gln Thr Arg Cys Ile Arg Ala Phe Pro Asn Lys Gln 
            180                 185                 190


Gly Tyr Val Leu Ser Ser Ile Glu Gly Arg Val Ala Val Glu Tyr Leu 
        195                 200                 205


Asp Pro Ser Pro Glu Val Gln Lys Lys Lys Tyr Ala Phe Lys Cys His 
    210                 215                 220


Arg Leu Lys Glu Asn Asn Ile Glu Gln Ile Tyr Pro Val Asn Ala Ile 
225                 230                 235                 240


Ser Phe His Asn Ile His Asn Thr Phe Ala Thr Gly Gly Ser Asp Gly 
                245                 250                 255


Phe Val Asn Ile Trp Asp Pro Phe Asn Lys Lys Arg Leu Cys Gln Phe 
            260                 265                 270


His Arg Tyr Pro Thr Ser Ile Ala Ser Leu Ala Phe Ser Asn Asp Gly 
        275                 280                 285


Thr Thr Leu Ala Ile Ala Ser Ser Tyr Met Tyr Glu Met Asp Asp Thr 
    290                 295                 300


Glu His Pro Glu Asp Gly Ile Phe Ile Arg Gln Val Thr Asp Ala Glu 
305                 310                 315                 320


Thr Lys Pro Lys 



<210>  7431
<211>  2764
<212>  DNA
<213>  Homo sapiens

<400>  7431
agcggtttcc ctttgagccg gaacaggatg actgggttga ccgatgctgg gcagctgagc     60

ggaccaatcg gccccctaga ctgagacgtt ggcgtttgaa atcagccaat ggcaggtcta    120

cactggagct tcctctccgc ctccttcgcc tagcctgcga gtgttctgag ggaagcaagg    180

aggcggcggc ggccgcagcg agtggcgagt agtggaaacg ttgcttctga ggggagccca    240

agatgaccgg ttctaacgag ttcaagctga accagccacc cgaggatggc atctcctccg    300

tgaagttcag ccccaacacc tcccagttcc tgcttgtctc ctcctgggac acgtccgtgc    360

gtctctacga tgtgccggcc aactccatgc ggctcaagta ccagcacacc ggcgccgtcc    420

tggactgcgc cttctacgat ccaacgcatg cctggagtgg aggactagat catcaattga    480

aaatgcatga tttgaacact gatcaagaaa atcttgttgg gacccatgat gcccctatca    540

gatgtgttga atactgtcca gaagtgaatg tgatggtcac tggaagttgg gatcagacag    600

ttaaactgtg ggatcccaga actccttgta atgctgggac cttctctcag cctgaaaagg    660

tatataccct ctcagtgtct ggagaccggc tgattgtggg aacagcaggc cgcagagtgt    720

tggtgtggga cttacggaac atgggttacg tgcagcagcg cagggagtcc agcctgaaat    780

accagactcg ctgcatacga gcgtttccaa acaagcaggg ttatgtatta agctctattg    840

aaggccgagt ggcagttgag tatttggacc caagccctga ggtacagaag aagaagtatg    900

ccttcaaatg tcacagacta aaagaaaata atattgagca gatttaccca gtcaatgcca    960

tttcttttca caatatccac aatacatttg ccacaggtgg ttctgatggc tttgtaaata   1020

tttgggatcc atttaacaaa aagcgactgt gccaattcca tcggtacccc acgagcatcg   1080

catcacttgc cttcagtaat gatgggacta cgcttgcaat agcgtcatca tatatgtatg   1140

aaatggatga cacagaacat cctgaagatg gtatcttcat tcgccaagtg acagatgcag   1200

aaacaaaacc caagtcacca tgtacttgac aagatttcat ttacttaagt gccatgttga   1260

tgataataaa acaattcgta ctccccaatg gtggatttat tactattaaa gaaaccaggg   1320

aaaatattaa ttttaatatt ataacaacct gaaaataatg gaaaagaggt ttttgaattt   1380

ttttttttaa ataaacacct tcttaagtgc atgagatggt ttgatggttt gctgcattaa   1440

aggtatttgg gcaaacaaaa ttggagggca agtgactgca gttttgagaa tcagttttga   1500

ccttgatgat tttttgtttc cactgtggaa ataaatgttt gtaaataagt gtaataaaaa   1560

tccctttgca ttctttctgg accttaaatg gtagaggaaa aggctcgtga gccatttgtt   1620

tcttttgctg gttatagttg ctaattctaa agctgcttca gactgcttca tgaggaggtt   1680

aatctacaat taaacaatat ttcctcttgg ccgtccatta ttttctgaag cagatggttc   1740

atcatttcct gggctgttaa acaaagcgag gttaaggtta gactcttggg aatcagctag   1800

ttttcaatct tattagggtg cagaaggaaa actaataaga aaacctccta atatcatttt   1860

gtgactgtaa acaattattt attagcaaac aattgatccc agaagggcaa attgtttgag   1920

tcagtaatga gctgagaaaa gacagagcat atctgtgtat ttggaaaaat aattgtaacg   1980

taattgcagt gcatttagac aggcatctat ttggacctgt ttctatctct aaatgaattt   2040

ttggaaacat taatgaggtt tacatatttc tctgacattt atatagttct tatgtccatt   2100

tcagttgacc agccgctggt gattaaagtt aaaaagaaaa aaattatagt gagaatgaga   2160

ttcatttcaa tgtaatgcac taaagcagaa cacgaactta gcttggccta ttctaggtag   2220

ttccaaatag tatttttgtt gtcaaacttt aaaatttata ttaatttgca aatgtatgtc   2280

tctgagtagg acttggacct ttcctgagat ttattttatc cgtgatgtat tttttttaat   2340

tcttttgata cagagaaggg tctttttttt tttaagtatt tcagtgaaaa cttggtgtaa   2400

gtctgaaccc atcttttgaa atgtattttc ttcattgcag gtccacctaa tcatcctgtg   2460

aaagtggttt ctctatggaa agctttgttt gcttcctaca aatacatgct tattccttaa   2520

gggatgtgtt agagttactg tggatttctc tgttttctgt cttacaagaa acttgtctat   2580

gtaccttaat actttgttta ggatgaggag tctttgtgtc cctgtacagt agtctgacgt   2640

atttcccctt ctgtccccta gtaagcccag ttgctgtatc tgaacagttt gagctctttt   2700

tgtaatatac tctaaacctg ttatttctgt gctaataaac gagatgcaga acccttgaat   2760

gttg                                                                2764


<210>  7432
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  7432

Met Thr Gly Ser Asn Glu Phe Lys Leu Asn Gln Pro Pro Glu Asp Gly 
1               5                   10                  15


Ile Ser Ser Val Lys Phe Ser Pro Asn Thr Ser Gln Phe Leu Leu Val 
            20                  25                  30


Ser Ser Trp Asp Thr Ser Val Arg Leu Tyr Asp Val Pro Ala Asn Ser 
        35                  40                  45


Met Arg Leu Lys Tyr Gln His Thr Gly Ala Val Leu Asp Cys Ala Phe 
    50                  55                  60


Tyr Asp Pro Thr His Ala Trp Ser Gly Gly Leu Asp His Gln Leu Lys 
65                  70                  75                  80


Met His Asp Leu Asn Thr Asp Gln Glu Asn Leu Val Gly Thr His Asp 
                85                  90                  95


Ala Pro Ile Arg Cys Val Glu Tyr Cys Pro Glu Val Asn Val Met Val 
            100                 105                 110


Thr Gly Ser Trp Asp Gln Thr Val Lys Leu Trp Asp Pro Arg Thr Pro 
        115                 120                 125


Cys Asn Ala Gly Thr Phe Ser Gln Pro Glu Lys Val Tyr Thr Leu Ser 
    130                 135                 140


Val Ser Gly Asp Arg Leu Ile Val Gly Thr Ala Gly Arg Arg Val Leu 
145                 150                 155                 160


Val Trp Asp Leu Arg Asn Met Gly Tyr Val Gln Gln Arg Arg Glu Ser 
                165                 170                 175


Ser Leu Lys Tyr Gln Thr Arg Cys Ile Arg Ala Phe Pro Asn Lys Gln 
            180                 185                 190


Gly Tyr Val Leu Ser Ser Ile Glu Gly Arg Val Ala Val Glu Tyr Leu 
        195                 200                 205


Asp Pro Ser Pro Glu Val Gln Lys Lys Lys Tyr Ala Phe Lys Cys His 
    210                 215                 220


Arg Leu Lys Glu Asn Asn Ile Glu Gln Ile Tyr Pro Val Asn Ala Ile 
225                 230                 235                 240


Ser Phe His Asn Ile His Asn Thr Phe Ala Thr Gly Gly Ser Asp Gly 
                245                 250                 255


Phe Val Asn Ile Trp Asp Pro Phe Asn Lys Lys Arg Leu Cys Gln Phe 
            260                 265                 270


His Arg Tyr Pro Thr Ser Ile Ala Ser Leu Ala Phe Ser Asn Asp Gly 
        275                 280                 285


Thr Thr Leu Ala Ile Ala Ser Ser Tyr Met Tyr Glu Met Asp Asp Thr 
    290                 295                 300


Glu His Pro Glu Asp Gly Ile Phe Ile Arg Gln Val Thr Asp Ala Glu 
305                 310                 315                 320


Thr Lys Pro Lys Ser Pro Cys Thr 
                325


<210>  7433
<211>  137
<212>  DNA
<213>  Homo sapiens

<400>  7433
gtgttcttca atccttgagg atcccaaatg gaagcccagg gaatggtagc tggggacaac     60

cccagatgtt caccggacct gtggtccttc tagattctcc gactcttaaa gtcttgtaat    120

aaatatctta cacgtat                                                   137


<210>  7434
<211>  6797
<212>  DNA
<213>  Homo sapiens

<400>  7434
ctccgccgca aactttttcc tccccatcct gtcgcggctc gaaaggaatg gaaaatggcg     60

gcctagacgc ggagtttcct gcccgacccg cggcggctcc ggcggcgcca tgacgcgctg    120

ggtgcccacc aagcgcgagg agaagtacgg cgtggctttt tataactatg atgccagagg    180

agcggatgaa ctttctttac agatcggaga cactgtgcac atcttagaaa catatgaagg    240

gtggtaccga ggttacacgt tacgaaaaaa gtctaagaag ggtatatttc ctgcttcata    300

tattcatctt aaagaagcga tagttgaagg aaaagggcaa catgaaacag tcatcccggg    360

tgacctcccc ctcatccagg aagtcaccac gacactccga gagtggtcca ccatctggag    420

gcagctctac gtgcaagata acagggagat gtttcgaagt gtgcggcaca tgatctatga    480

ccttattgaa tggcgatcac aaattctttc tggaactctg cctcaggatg aactcaaaga    540

actgaagaag aaggtcacag ccaaaattga ttatggaaac agaattctag atttggacct    600

ggtggttaga gatgaagatg ggaatatttt ggatccagaa ttaactagca cgattagtct    660

cttcagagct catgaaatag cttctaaaca agtggaggaa aggttacaag aggaaaaatc    720

tcaaaagcag aacatagata ttaacagaca agccaagttt gctgcaaccc cttctctggc    780

cttgtttgtg aacctcaaaa atgtggtttg taaaatagga gaagatgctg aagtcctcat    840

gtctctatat gaccctgtgg agtccaaatt catcagtgag aactacctgg ttcgctggtc    900

cagttcagga ttacctaaag acatagacag attacataat ttgcgagccg tgtttactga    960

cctcggaagc aaagacctga aaagggagaa aatcagtttt gtctgtcaga ttgttcgcgt   1020

gggtcgcatg gagctgaggg acaacaacac caggaaactg acctcggggt tgcggcgacc   1080

ttttggagtg gctgtgatgg atgtaacaga tataataaat ggaaaagtag atgatgaaga   1140

taagcagcat ttcattccct ttcagccggt ggcaggggag aatgacttcc ttcagactgt   1200

tataaacaaa gtcatcgctg ccaaagaagt caaccacaag gggcagggtt tgtgggtaac   1260

attgaaatta cttcctggag atatccatca gatccgaaaa gagtttccgc atttagtgga   1320

caggaccaca gctgtggctc gaaaaacagg gtttccggag ataatcatgc ctggtgatgt   1380

tcgaaatgat atctatgtaa cattagttca aggagatttt gataaaggaa gcaaaacaac   1440

agcgaagaac gtggaggtca cggtgtctgt gtacgatgag gatgggaaac gattagagca   1500

tgtgattttc ccgggtgctg gtgatgaagc gatttcagag tacaaatctg tgatttacta   1560

ccaagtaaag cagccacgct ggtttgagac tgttaaggtg gccattccca tcgaggacgt   1620

taaccgcagt caccttcggt ttaccttccg ccacaggtca tcacaggact ctaaggataa   1680

atctgagaaa atatttgcac tagcatttgt caagctgatg agatacgatg gtaccaccct   1740

gcgagacgga gagcacgatc ttatcgtcta taaggccgaa gcaaagaagc tggaagatgc   1800

tgccacgtac ttgagtctgc cctccacgaa ggcagagttg gaagaaaagg gccactcggc   1860

caccggcaag agcatgcaga gccttgggag ctgcaccatt agcaaggact ccttccagat   1920

ctccacgctc gtgtgctcca ccaaactgac tcagaacgtg gaccttctgg ggctcttgaa   1980

atggcgctcc aacaccagcc tgctgcagca gaacttgagg cagctgatga aagtcgatgg   2040

tggtgaagta gtgaagtttc ttcaggacac gttggatgcc ctcttcaaca tcatgatgga   2100

gaactcagag agtgagactt ttgacacgtt agtctttgat gctctggtat ttatcattgg   2160

actgattgct gatagaaaat ttcagcattt taatcctgtt ttggaaactt acattaagaa   2220

acactttagt gcaacgttag cctacacgaa gttgacaaaa gtgttgaaga actacgtgga   2280

cggtgctgag aagccgggag taaatgagca gctgtacaaa gccatgaaag cgctagaatc   2340

catcttcaag ttcatcgtgc gctccaggat cctgttcaat caactgtatg aaaacaaggg   2400

agaggctgac ttcgtggaat ctttgctgca gctcttcagg tccatcaatg acatgatgag   2460

cagcatgtca gaccagaccg tccgggtgaa gggggcagca ctgaaatact taccaacgat   2520

cgtcaacgat gtgaaattgg tgtttgatcc caaagagctc agcaaaatgt ttactgaatt   2580

catcctcaat gttcccatgg gcttgctgac catccagaaa ctctactgct tgatcgaaat   2640

cgtccacagt gacctcttca cacagcatga ctgcagagag atcctgcttc ccatgatgac   2700

cgatcagctc aagtaccatc tggagagaca ggaggacctg gaggcctgct gtcagctgct   2760

cagccacatc ctggaggtgc tgtacaggaa ggacgtgggg ccaacccaga ggcacgtcca   2820

gattatcatg gagaaacttc tccggaccgt gaaccgaacc gtcatttcca tgggacgaga   2880

ttctgaactc attggaaact tcgtggcttg catgacagct attttacgac aaatggaaga   2940

ttaccattat gcccacttga tcaagacttt tgggaaaatg aggactgatg tggtagattt   3000

cctaatggaa acattcatca tgtttaagaa cctcattgga aagaacgttt accccttcga   3060

ctgggtgatc atgaacatgg tgcaaaataa agtcttcctg cgagcaatta atcagtatgc   3120

agatatgctg aacaaaaaat ttctggatca agccaacttt gagctacagc tgtggaacaa   3180

ctactttcac ctggctgttg ctttccttac tcaagagtcc ctgcaactgg agaatttttc   3240

aagtgccaag agagccaaaa tccttaacaa gtacggagat atgaggagac agattggctt   3300

tgaaatcaga gacatgtggt acaaccttgg tcaacacaag ataaagttca ttccagaaat   3360

ggtgggccca atattagaaa tgacattaat tcccgagacg gagctgcgca aagccaccat   3420

ccccatcttc tttgatatga tgcagtgtga attccattcg acccgaagct tccaaatgtt   3480

tgaaaatgag atcatcacca agctggatca tgaagtcgaa ggaggcagag gagacgaaca   3540

gtacaaagtg ttatttgata aaatccttct ggaacactgc aggaagcaca aatacctcgc   3600

caaaacagga gaaacttttg taaaactcgt tgtgcgctta atggaaaggc ttttggatta   3660

tagaaccatc atgcacgacg agaacaaaga aaaccgcatg agctgcaccg tcaatgtgct   3720

gaatttctac aaagaaattg aaagagaaga aatgtatata aggtatttgt acaagctctg   3780

tgacctgcac aaggagtgtg ataactacac cgaagcggct tacaccttgc ttctccatgc   3840

aaagcttctt aagtggtcgg aggatgtgtg tgtggcccac ctcacccagc gggacgggta   3900

ccaggccacc acgcagggac agctgaagga gcagctctac caggaaatca tccactactt   3960

cgacaaaggc aagatgtggg aggaggccat tgccttgggc aaggagctag ccgagcagta   4020

tgagaacgaa atgtttgatt atgagcaact cagcgaattg ctgaaaaaac aggctcagtt   4080

ttatgaaaac atcgtcaaag tgatcaggcc caagcctgac tattttgctg ttggctacta   4140

cggacaaggg ttccccacat tcctgcgggg aaaagttttc atttaccgag ggaaagagta   4200

tgagcgccgg gaagattttg aggctcggct cttaactcag tttccaaacg ccgagaaaat   4260

gaagacaaca tctccaccag gcgacgatat taaaaactct cctggccagt atattcagtg   4320

cttcacagtg aagcccaaac tcgatctgcc tcctaagttt cacaggccag tgtcagagca   4380

gattgtaagt ttttacaggg tgaacgaggt ccagcgattt gaatattctc ggccaatccg   4440

gaagggagag aaaaacccag acaatgaatt tgcgaatatg tggatcgaga gaaccatata   4500

tacaactgca tataaattac ctggaatttt aaggtggttt gaggtcaagt ctgttttcat   4560

ggtggaaatc agccccctgg agaatgccat tgagaccatg cagctgacga acgacaagat   4620

caacagcatg gtgcagcagc acctggatga ccccagcctg cccatcaacc cgctctccat   4680

gctcctgaac ggcatcgtgg acccagctgt catggggggc ttcgcaaact acgaaaaggc   4740

cttctttaca gaccggtacc tgcaggagca ccctgaggcc catgaaaaga tcgagaagct   4800

caaggacctg attgcttggc agattccttt tctggccgaa gggatcagaa tccatggaga   4860

caaagtcacg gaggcactga ggccgttcca cgagaggatg gaggcctgtt tcaaacagct   4920

gaaggaaaag gtggagaaag agtacggcgt ccgaatcatg ccctcaagtc tggatgatag   4980

aagaggcagc cgcccccggt ccatggtgcg gtccttcacg atgccttcct catcccgccc   5040

tctgtctgtg gcctctgtct cttccctctc atcggacagc accccttcca gaccaggctc   5100

cgacgggttt gccctggagc ctctcctgcc aaagaaaatg cactccaggt cccaggacaa   5160

gctggacaag gatgacctgg agaaggagaa gaaggacaag aagaaggaaa aaaggaacag   5220

caaacatcaa gagatatttg agaaagaatt taaacccacc gacatttccc tgcagcagtc   5280

tgaggctgtg atcctttcgg aaacgataag tcccctgcgg ccccagagac cgaagagcca   5340

ggtgatgaac gtcattggaa gcgaaaggcg cttctcggtg tccccctcgt caccgtcctc   5400

ccagcaaaca ccccctccag ttacaccaag ggccaagctc agcttcagca tgcagtcgag   5460

cttggagctg aacggcatga cgggggcgga cgtggccgat gtcccacccc ctctgcctct   5520

caaaggcagc gtggcagatt acgggaattt gatggaaaac caggacttgc tgggctcgcc   5580

aacacctcca cctccccctc cacaccagag gcatctgcca cctccactgc ccagcaaaac   5640

tccgcctcct ccccctccaa agacaactcg caagcaggca tcggtggact ccgggatcgt   5700

gcagtgacgt cgcaagcctc tctggaaaga gtgtgctgcc cctccccatc tccatgccct   5760

ctccttctgt gtcccctgag tctgctgttt acctcattgg gcctgtgatg ttaacatttc   5820

gtgcgactgc tttttcttca aaggagttca gttctcacca tggagtgagt ggcctttagc   5880

gtcatggagc aaggtgggtc tgggaggtag atatgggtcc gggatgtgct atcgtagtta   5940

tcagagttgg gggcctctga gtgtgtctgg ctctgagaga gtctgagtct tgcccaaaca   6000

ttctttcttt ttgtgccaaa tgacttgcat ttgcaaagag ctcaattgct ctgagctcag   6060

ccaagtagga gaggctaggc catcactctt aggaagctgt gtagtgatga tgtataagaa   6120

tcctcctcac tgtcatggga tgttgtatcc agcccctcct tgttccagcc ggtggtgtga   6180

cttcgttggt tgaggtgtgt ctccaaccta catcagacca tgaagttcaa cccctccagg   6240

gaagctcctg atttcccctg cataattgaa aataggatat ttctcagcta ttgaacagtt   6300

actaatttat ggggtggaaa cagcattaag aatactgaat caaatggaaa aacaaatgaa   6360

tacaggaaga taagtgttcg ttcttttctg aaaaagagta tgtgtaccac aagagctggt   6420

tttaattggg tgaattgttt ttgtcctcat tctgtacaga aatttgtata tatgatggtt   6480

cttagaactt gttttaattt ttgtggtcct tccgtttatt ataataggcg tccaccaatg   6540

attatccata tgtgttctta atttttaact gctggaagtg ttaaaacaca cacacacaca   6600

cacacacatt ttttttttga gaactccaaa gtcctgaaaa ttttggtgga caatgatttt   6660

taaaaaacta actttgtata acctaatatt tgtattctct catctatatt tttttattca   6720

ctataatcat gatactcttc taatagactt aaaagttaat cattgacaac gaaaaataaa   6780

atgttatttt aaaagac                                                  6797


<210>  7435
<211>  1865
<212>  PRT
<213>  Homo sapiens

<400>  7435

Met Thr Arg Trp Val Pro Thr Lys Arg Glu Glu Lys Tyr Gly Val Ala 
1               5                   10                  15


Phe Tyr Asn Tyr Asp Ala Arg Gly Ala Asp Glu Leu Ser Leu Gln Ile 
            20                  25                  30


Gly Asp Thr Val His Ile Leu Glu Thr Tyr Glu Gly Trp Tyr Arg Gly 
        35                  40                  45


Tyr Thr Leu Arg Lys Lys Ser Lys Lys Gly Ile Phe Pro Ala Ser Tyr 
    50                  55                  60


Ile His Leu Lys Glu Ala Ile Val Glu Gly Lys Gly Gln His Glu Thr 
65                  70                  75                  80


Val Ile Pro Gly Asp Leu Pro Leu Ile Gln Glu Val Thr Thr Thr Leu 
                85                  90                  95


Arg Glu Trp Ser Thr Ile Trp Arg Gln Leu Tyr Val Gln Asp Asn Arg 
            100                 105                 110


Glu Met Phe Arg Ser Val Arg His Met Ile Tyr Asp Leu Ile Glu Trp 
        115                 120                 125


Arg Ser Gln Ile Leu Ser Gly Thr Leu Pro Gln Asp Glu Leu Lys Glu 
    130                 135                 140


Leu Lys Lys Lys Val Thr Ala Lys Ile Asp Tyr Gly Asn Arg Ile Leu 
145                 150                 155                 160


Asp Leu Asp Leu Val Val Arg Asp Glu Asp Gly Asn Ile Leu Asp Pro 
                165                 170                 175


Glu Leu Thr Ser Thr Ile Ser Leu Phe Arg Ala His Glu Ile Ala Ser 
            180                 185                 190


Lys Gln Val Glu Glu Arg Leu Gln Glu Glu Lys Ser Gln Lys Gln Asn 
        195                 200                 205


Ile Asp Ile Asn Arg Gln Ala Lys Phe Ala Ala Thr Pro Ser Leu Ala 
    210                 215                 220


Leu Phe Val Asn Leu Lys Asn Val Val Cys Lys Ile Gly Glu Asp Ala 
225                 230                 235                 240


Glu Val Leu Met Ser Leu Tyr Asp Pro Val Glu Ser Lys Phe Ile Ser 
                245                 250                 255


Glu Asn Tyr Leu Val Arg Trp Ser Ser Ser Gly Leu Pro Lys Asp Ile 
            260                 265                 270


Asp Arg Leu His Asn Leu Arg Ala Val Phe Thr Asp Leu Gly Ser Lys 
        275                 280                 285


Asp Leu Lys Arg Glu Lys Ile Ser Phe Val Cys Gln Ile Val Arg Val 
    290                 295                 300


Gly Arg Met Glu Leu Arg Asp Asn Asn Thr Arg Lys Leu Thr Ser Gly 
305                 310                 315                 320


Leu Arg Arg Pro Phe Gly Val Ala Val Met Asp Val Thr Asp Ile Ile 
                325                 330                 335


Asn Gly Lys Val Asp Asp Glu Asp Lys Gln His Phe Ile Pro Phe Gln 
            340                 345                 350


Pro Val Ala Gly Glu Asn Asp Phe Leu Gln Thr Val Ile Asn Lys Val 
        355                 360                 365


Ile Ala Ala Lys Glu Val Asn His Lys Gly Gln Gly Leu Trp Val Thr 
    370                 375                 380


Leu Lys Leu Leu Pro Gly Asp Ile His Gln Ile Arg Lys Glu Phe Pro 
385                 390                 395                 400


His Leu Val Asp Arg Thr Thr Ala Val Ala Arg Lys Thr Gly Phe Pro 
                405                 410                 415


Glu Ile Ile Met Pro Gly Asp Val Arg Asn Asp Ile Tyr Val Thr Leu 
            420                 425                 430


Val Gln Gly Asp Phe Asp Lys Gly Ser Lys Thr Thr Ala Lys Asn Val 
        435                 440                 445


Glu Val Thr Val Ser Val Tyr Asp Glu Asp Gly Lys Arg Leu Glu His 
    450                 455                 460


Val Ile Phe Pro Gly Ala Gly Asp Glu Ala Ile Ser Glu Tyr Lys Ser 
465                 470                 475                 480


Val Ile Tyr Tyr Gln Val Lys Gln Pro Arg Trp Phe Glu Thr Val Lys 
                485                 490                 495


Val Ala Ile Pro Ile Glu Asp Val Asn Arg Ser His Leu Arg Phe Thr 
            500                 505                 510


Phe Arg His Arg Ser Ser Gln Asp Ser Lys Asp Lys Ser Glu Lys Ile 
        515                 520                 525


Phe Ala Leu Ala Phe Val Lys Leu Met Arg Tyr Asp Gly Thr Thr Leu 
    530                 535                 540


Arg Asp Gly Glu His Asp Leu Ile Val Tyr Lys Ala Glu Ala Lys Lys 
545                 550                 555                 560


Leu Glu Asp Ala Ala Thr Tyr Leu Ser Leu Pro Ser Thr Lys Ala Glu 
                565                 570                 575


Leu Glu Glu Lys Gly His Ser Ala Thr Gly Lys Ser Met Gln Ser Leu 
            580                 585                 590


Gly Ser Cys Thr Ile Ser Lys Asp Ser Phe Gln Ile Ser Thr Leu Val 
        595                 600                 605


Cys Ser Thr Lys Leu Thr Gln Asn Val Asp Leu Leu Gly Leu Leu Lys 
    610                 615                 620


Trp Arg Ser Asn Thr Ser Leu Leu Gln Gln Asn Leu Arg Gln Leu Met 
625                 630                 635                 640


Lys Val Asp Gly Gly Glu Val Val Lys Phe Leu Gln Asp Thr Leu Asp 
                645                 650                 655


Ala Leu Phe Asn Ile Met Met Glu Asn Ser Glu Ser Glu Thr Phe Asp 
            660                 665                 670


Thr Leu Val Phe Asp Ala Leu Val Phe Ile Ile Gly Leu Ile Ala Asp 
        675                 680                 685


Arg Lys Phe Gln His Phe Asn Pro Val Leu Glu Thr Tyr Ile Lys Lys 
    690                 695                 700


His Phe Ser Ala Thr Leu Ala Tyr Thr Lys Leu Thr Lys Val Leu Lys 
705                 710                 715                 720


Asn Tyr Val Asp Gly Ala Glu Lys Pro Gly Val Asn Glu Gln Leu Tyr 
                725                 730                 735


Lys Ala Met Lys Ala Leu Glu Ser Ile Phe Lys Phe Ile Val Arg Ser 
            740                 745                 750


Arg Ile Leu Phe Asn Gln Leu Tyr Glu Asn Lys Gly Glu Ala Asp Phe 
        755                 760                 765


Val Glu Ser Leu Leu Gln Leu Phe Arg Ser Ile Asn Asp Met Met Ser 
    770                 775                 780


Ser Met Ser Asp Gln Thr Val Arg Val Lys Gly Ala Ala Leu Lys Tyr 
785                 790                 795                 800


Leu Pro Thr Ile Val Asn Asp Val Lys Leu Val Phe Asp Pro Lys Glu 
                805                 810                 815


Leu Ser Lys Met Phe Thr Glu Phe Ile Leu Asn Val Pro Met Gly Leu 
            820                 825                 830


Leu Thr Ile Gln Lys Leu Tyr Cys Leu Ile Glu Ile Val His Ser Asp 
        835                 840                 845


Leu Phe Thr Gln His Asp Cys Arg Glu Ile Leu Leu Pro Met Met Thr 
    850                 855                 860


Asp Gln Leu Lys Tyr His Leu Glu Arg Gln Glu Asp Leu Glu Ala Cys 
865                 870                 875                 880


Cys Gln Leu Leu Ser His Ile Leu Glu Val Leu Tyr Arg Lys Asp Val 
                885                 890                 895


Gly Pro Thr Gln Arg His Val Gln Ile Ile Met Glu Lys Leu Leu Arg 
            900                 905                 910


Thr Val Asn Arg Thr Val Ile Ser Met Gly Arg Asp Ser Glu Leu Ile 
        915                 920                 925


Gly Asn Phe Val Ala Cys Met Thr Ala Ile Leu Arg Gln Met Glu Asp 
    930                 935                 940


Tyr His Tyr Ala His Leu Ile Lys Thr Phe Gly Lys Met Arg Thr Asp 
945                 950                 955                 960


Val Val Asp Phe Leu Met Glu Thr Phe Ile Met Phe Lys Asn Leu Ile 
                965                 970                 975


Gly Lys Asn Val Tyr Pro Phe Asp Trp Val Ile Met Asn Met Val Gln 
            980                 985                 990


Asn Lys Val Phe Leu Arg Ala Ile Asn Gln Tyr Ala Asp Met Leu Asn 
        995                 1000                1005


Lys Lys Phe Leu Asp Gln Ala Asn Phe Glu Leu Gln Leu Trp Asn Asn 
    1010                1015                1020


Tyr Phe His Leu Ala Val Ala Phe Leu Thr Gln Glu Ser Leu Gln Leu 
1025                1030                1035                1040


Glu Asn Phe Ser Ser Ala Lys Arg Ala Lys Ile Leu Asn Lys Tyr Gly 
                1045                1050                1055


Asp Met Arg Arg Gln Ile Gly Phe Glu Ile Arg Asp Met Trp Tyr Asn 
            1060                1065                1070


Leu Gly Gln His Lys Ile Lys Phe Ile Pro Glu Met Val Gly Pro Ile 
        1075                1080                1085


Leu Glu Met Thr Leu Ile Pro Glu Thr Glu Leu Arg Lys Ala Thr Ile 
    1090                1095                1100


Pro Ile Phe Phe Asp Met Met Gln Cys Glu Phe His Ser Thr Arg Ser 
1105                1110                1115                1120


Phe Gln Met Phe Glu Asn Glu Ile Ile Thr Lys Leu Asp His Glu Val 
                1125                1130                1135


Glu Gly Gly Arg Gly Asp Glu Gln Tyr Lys Val Leu Phe Asp Lys Ile 
            1140                1145                1150


Leu Leu Glu His Cys Arg Lys His Lys Tyr Leu Ala Lys Thr Gly Glu 
        1155                1160                1165


Thr Phe Val Lys Leu Val Val Arg Leu Met Glu Arg Leu Leu Asp Tyr 
    1170                1175                1180


Arg Thr Ile Met His Asp Glu Asn Lys Glu Asn Arg Met Ser Cys Thr 
1185                1190                1195                1200


Val Asn Val Leu Asn Phe Tyr Lys Glu Ile Glu Arg Glu Glu Met Tyr 
                1205                1210                1215


Ile Arg Tyr Leu Tyr Lys Leu Cys Asp Leu His Lys Glu Cys Asp Asn 
            1220                1225                1230


Tyr Thr Glu Ala Ala Tyr Thr Leu Leu Leu His Ala Lys Leu Leu Lys 
        1235                1240                1245


Trp Ser Glu Asp Val Cys Val Ala His Leu Thr Gln Arg Asp Gly Tyr 
    1250                1255                1260


Gln Ala Thr Thr Gln Gly Gln Leu Lys Glu Gln Leu Tyr Gln Glu Ile 
1265                1270                1275                1280


Ile His Tyr Phe Asp Lys Gly Lys Met Trp Glu Glu Ala Ile Ala Leu 
                1285                1290                1295


Gly Lys Glu Leu Ala Glu Gln Tyr Glu Asn Glu Met Phe Asp Tyr Glu 
            1300                1305                1310


Gln Leu Ser Glu Leu Leu Lys Lys Gln Ala Gln Phe Tyr Glu Asn Ile 
        1315                1320                1325


Val Lys Val Ile Arg Pro Lys Pro Asp Tyr Phe Ala Val Gly Tyr Tyr 
    1330                1335                1340


Gly Gln Gly Phe Pro Thr Phe Leu Arg Gly Lys Val Phe Ile Tyr Arg 
1345                1350                1355                1360


Gly Lys Glu Tyr Glu Arg Arg Glu Asp Phe Glu Ala Arg Leu Leu Thr 
                1365                1370                1375


Gln Phe Pro Asn Ala Glu Lys Met Lys Thr Thr Ser Pro Pro Gly Asp 
            1380                1385                1390


Asp Ile Lys Asn Ser Pro Gly Gln Tyr Ile Gln Cys Phe Thr Val Lys 
        1395                1400                1405


Pro Lys Leu Asp Leu Pro Pro Lys Phe His Arg Pro Val Ser Glu Gln 
    1410                1415                1420


Ile Val Ser Phe Tyr Arg Val Asn Glu Val Gln Arg Phe Glu Tyr Ser 
1425                1430                1435                1440


Arg Pro Ile Arg Lys Gly Glu Lys Asn Pro Asp Asn Glu Phe Ala Asn 
                1445                1450                1455


Met Trp Ile Glu Arg Thr Ile Tyr Thr Thr Ala Tyr Lys Leu Pro Gly 
            1460                1465                1470


Ile Leu Arg Trp Phe Glu Val Lys Ser Val Phe Met Val Glu Ile Ser 
        1475                1480                1485


Pro Leu Glu Asn Ala Ile Glu Thr Met Gln Leu Thr Asn Asp Lys Ile 
    1490                1495                1500


Asn Ser Met Val Gln Gln His Leu Asp Asp Pro Ser Leu Pro Ile Asn 
1505                1510                1515                1520


Pro Leu Ser Met Leu Leu Asn Gly Ile Val Asp Pro Ala Val Met Gly 
                1525                1530                1535


Gly Phe Ala Asn Tyr Glu Lys Ala Phe Phe Thr Asp Arg Tyr Leu Gln 
            1540                1545                1550


Glu His Pro Glu Ala His Glu Lys Ile Glu Lys Leu Lys Asp Leu Ile 
        1555                1560                1565


Ala Trp Gln Ile Pro Phe Leu Ala Glu Gly Ile Arg Ile His Gly Asp 
    1570                1575                1580


Lys Val Thr Glu Ala Leu Arg Pro Phe His Glu Arg Met Glu Ala Cys 
1585                1590                1595                1600


Phe Lys Gln Leu Lys Glu Lys Val Glu Lys Glu Tyr Gly Val Arg Ile 
                1605                1610                1615


Met Pro Ser Ser Leu Asp Asp Arg Arg Gly Ser Arg Pro Arg Ser Met 
            1620                1625                1630


Val Arg Ser Phe Thr Met Pro Ser Ser Ser Arg Pro Leu Ser Val Ala 
        1635                1640                1645


Ser Val Ser Ser Leu Ser Ser Asp Ser Thr Pro Ser Arg Pro Gly Ser 
    1650                1655                1660


Asp Gly Phe Ala Leu Glu Pro Leu Leu Pro Lys Lys Met His Ser Arg 
1665                1670                1675                1680


Ser Gln Asp Lys Leu Asp Lys Asp Asp Leu Glu Lys Glu Lys Lys Asp 
                1685                1690                1695


Lys Lys Lys Glu Lys Arg Asn Ser Lys His Gln Glu Ile Phe Glu Lys 
            1700                1705                1710


Glu Phe Lys Pro Thr Asp Ile Ser Leu Gln Gln Ser Glu Ala Val Ile 
        1715                1720                1725


Leu Ser Glu Thr Ile Ser Pro Leu Arg Pro Gln Arg Pro Lys Ser Gln 
    1730                1735                1740


Val Met Asn Val Ile Gly Ser Glu Arg Arg Phe Ser Val Ser Pro Ser 
1745                1750                1755                1760


Ser Pro Ser Ser Gln Gln Thr Pro Pro Pro Val Thr Pro Arg Ala Lys 
                1765                1770                1775


Leu Ser Phe Ser Met Gln Ser Ser Leu Glu Leu Asn Gly Met Thr Gly 
            1780                1785                1790


Ala Asp Val Ala Asp Val Pro Pro Pro Leu Pro Leu Lys Gly Ser Val 
        1795                1800                1805


Ala Asp Tyr Gly Asn Leu Met Glu Asn Gln Asp Leu Leu Gly Ser Pro 
    1810                1815                1820


Thr Pro Pro Pro Pro Pro Pro His Gln Arg His Leu Pro Pro Pro Leu 
1825                1830                1835                1840


Pro Ser Lys Thr Pro Pro Pro Pro Pro Pro Lys Thr Thr Arg Lys Gln 
                1845                1850                1855


Ala Ser Val Asp Ser Gly Ile Val Gln 
            1860                1865


<210>  7436
<211>  4885
<212>  DNA
<213>  Homo sapiens

<400>  7436
agcttaattc gaagcagcat attgcaactg tttgggtgct atcttgaggc acaataatta     60

ccctataata ataatgtgtg ttttagtaaa ctggtcatta ttgtcataga gggctggaaa    120

gagtgtcttc ttaaagctca taaggaccct agggtactct gcaaatagca gagttctaaa    180

cctgaaggaa aaaattaagg ggaaaaaaaa ttgtgttagt ggtcagaagc cccgtgtcct    240

tatgcatcac ggcacagccc accctgtaat gacaagaagg tgttgtattc cactgacact    300

tgggggcttt tctgtgatct ctggggttgc tgcatgtaca tcctcagagg ctctctcaac    360

acagttacca agggtcaggt gggttactta gaccatctct ctagctcata ctttgtactt    420

ctgggggctg aaggtgacag gacagacccc atcccaagac tggggggctg attagagttg    480

ccaggcatcc cgtatatgca aagcatgtcc tgaattttgc aacttttgtc ctggatcctt    540

tattaatttg tcaggatgct ctaaatgtcc tgtattccgc tttttttttc taatcaatta    600

cagaattcag caataagagc tttattcaaa tttaactggg catcctatat ttgcaaaatc    660

tggcaaccct gcggctgagg aatgttgctg cccagcctgt gttcttggtt aatggacaag    720

gcagcaatgc ctgcgtccct ccattaatag tcacttagaa acactaattc ctcctttctg    780

gttatatttt aatgtccccg gggaagaagt caaataactc cacctgcagt tttctttagt    840

gaccaaaatt gcaaactctg tcacaggccc tttgtcacag ctgttttggt cccagagcta    900

gccgataggt ttcttgatga aataatgtct gcgaatccct ttctcagagc ggcacgcagt    960

gtgagcgtga gagaatctgc agtgacagcg ggtgatgggc gggaggtggt ggtggcaggt   1020

ggcgatggag acctccttaa aaccccaggt ggtgaatttc ttcttccctc ctccctggct   1080

cactgccttt tagcggctgt gacatggcca gggcgtgggg agcttctcca ggcacgcttg   1140

gctgaagaga taatgctgtc agaggacagc agttactaag tcttcctgcg agcaattaat   1200

cagtatgcag atatgctgaa caaaaaattt ctggatcaag ccaactttga gctacagctg   1260

tggaacaact actttcacct ggctgttgct ttccttactc aagagtccct gcaactggag   1320

aatttttcaa gtgccaagag agccaaaatc cttaacaagt acggagatat gaggagacag   1380

attggctttg aaatcagaga catgtggtac aaccttggtc aacacaagat aaagttcatt   1440

ccagaaatgg tgggcccaat attagaaatg acattaattc ccgagacgga gctgcgcaaa   1500

gccaccatcc ccatcttctt tgatatgatg cagtgtgaat tccattcgac ccgaagcttc   1560

caaatgtttg aaaatgagat catcaccaag ctggatcatg aagtcgaagg aggcagagga   1620

gacgaacagt acaaagtgtt atttgataaa atccttctgg aacactgcag gaagcacaaa   1680

tacctcgcca aaacaggaga aacttttgta aaactcgttg tgcgcttaat ggaaaggctt   1740

ttggattata gaaccatcat gcacgacgag aacaaagaaa accgcatgag ctgcaccgtc   1800

aatgtgctga atttctacaa agaaattgaa agagaagaaa tgtatataag gtatttgtac   1860

aagctctgtg acctgcacaa ggagtgtgat aactacaccg aagcggctta caccttgctt   1920

ctccatgcaa agcttcttaa gtggtcggag gatgtgtgtg tggcccacct cacccagcgg   1980

gacgggtacc aggccaccac gcagggacag ctgaaggagc agctctacca ggaaatcatc   2040

cactacttcg acaaaggcaa gatgtgggag gaggccattg ccttgggcaa ggagctagcc   2100

gagcagtatg agaacgaaat gtttgattat gagcaactca gcgaattgct gaaaaaacag   2160

gctcagtttt atgaaaacat cgtcaaagtg atcaggccca agcctgacta ttttgctgtt   2220

ggctactacg gacaagggtt ccccacattc ctgcggggaa aagttttcat ttaccgaggg   2280

aaagagtatg agcgccggga agattttgag gctcggctct taactcagtt tccaaacgcc   2340

gagaaaatga agacaacatc tccaccaggc gacgatatta aaaactctcc tggccagtat   2400

attcagtgct tcacagtgaa gcccaaactc gatctgcctc ctaagtttca caggccagtg   2460

tcagagcaga ttgtaagttt ttacagggtg aacgaggtcc agcgatttga atattctcgg   2520

ccaatccgga agggagagaa aaacccagac aatgaatttg cgaatatgtg gatcgagaga   2580

accatatata caactgcata taaattacct ggaattttaa ggtggtttga ggtcaagtct   2640

gttttcatgg tggaaatcag ccccctggag aatgccattg agaccatgca gctgacgaac   2700

gacaagatca acagcatggt gcagcagcac ctggatgacc ccagcctgcc catcaacccg   2760

ctctccatgc tcctgaacgg catcgtggac ccagctgtca tggggggctt cgcaaactac   2820

gaaaaggcct tctttacaga ccggtacctg caggagcacc ctgaggccca tgaaaagatc   2880

gagaagctca aggacctgat tgcttggcag attccttttc tggccgaagg gatcagaatc   2940

catggagaca aagtcacgga ggcactgagg ccgttccacg agaggatgga ggcctgtttc   3000

aaacagctga aggaaaaggt ggagaaagag tacggcgtcc gaatcatgcc ctcaagtctg   3060

gatgatagaa gaggcagccg cccccggtcc atggtgcggt ccttcacgat gccttcctca   3120

tcccgccctc tgtctgtggc ctctgtctct tccctctcat cggacagcac cccttccaga   3180

ccaggctccg acgggtttgc cctggagcct ctcctgccaa agaaaatgca ctccaggtcc   3240

caggacaagc tggacaagga tgacctggag aaggagaaga aggacaagaa gaaggaaaaa   3300

aggaacagca aacatcaaga gatatttgag aaagaattta aacccaccga catttccctg   3360

cagcagtctg aggctgtgat cctttcggaa acgataagtc ccctgcggcc ccagagaccg   3420

aagagccagg tgatgaacgt cattggaagc gaaaggcgct tctcggtgtc cccctcgtca   3480

ccgtcctccc agcaaacacc ccctccagtt acaccaaggg ccaagctcag cttcagcatg   3540

cagtcgagct tggagctgaa cggcatgacg ggggcggacg tggccgatgt cccaccccct   3600

ctgcctctca aaggcagcgt ggcagattac gggaatttga tggaaaacca ggacttgctg   3660

ggctcgccaa cacctccacc tccccctcca caccagaggc atctgccacc tccactgccc   3720

agcaaaactc cgcctcctcc ccctccaaag acaactcgca agcaggcatc ggtggactcc   3780

gggatcgtgc agtgacgtcg caagcctctc tggaaagagt gtgctgcccc tccccatctc   3840

catgccctct ccttctgtgt cccctgagtc tgctgtttac ctcattgggc ctgtgatgtt   3900

aacatttcgt gcgactgctt tttcttcaaa ggagttcagt tctcaccatg gagtgagtgg   3960

cctttagcgt catggagcaa ggtgggtctg ggaggtagat atgggtccgg gatgtgctat   4020

cgtagttatc agagttgggg gcctctgagt gtgtctggct ctgagagagt ctgagtcttg   4080

cccaaacatt ctttcttttt gtgccaaatg acttgcattt gcaaagagct caattgctct   4140

gagctcagcc aagtaggaga ggctaggcca tcactcttag gaagctgtgt agtgatgatg   4200

tataagaatc ctcctcactg tcatgggatg ttgtatccag cccctccttg ttccagccgg   4260

tggtgtgact tcgttggttg aggtgtgtct ccaacctaca tcagaccatg aagttcaacc   4320

cctccaggga agctcctgat ttcccctgca taattgaaaa taggatattt ctcagctatt   4380

gaacagttac taatttatgg ggtggaaaca gcattaagaa tactgaatca aatggaaaaa   4440

caaatgaata caggaagata agtgttcgtt cttttctgaa aaagagtatg tgtaccacaa   4500

gagctggttt taattgggtg aattgttttt gtcctcattc tgtacagaaa tttgtatata   4560

tgatggttct tagaacttgt tttaattttt gtggtccttc cgtttattat aataggcgtc   4620

caccaatgat tatccatatg tgttcttaat ttttaactgc tggaagtgtt aaaacacaca   4680

cacacacaca cacacatttt ttttttgaga actccaaagt cctgaaaatt ttggtggaca   4740

atgattttta aaaaactaac tttgtataac ctaatatttg tattctctca tctatatttt   4800

tttattcact ataatcatga tactcttcta atagacttaa aagttaatca ttgacaacga   4860

aaaataaaat gttattttaa aagac                                         4885


<210>  7437
<211>  860
<212>  PRT
<213>  Homo sapiens

<400>  7437

Met Leu Asn Lys Lys Phe Leu Asp Gln Ala Asn Phe Glu Leu Gln Leu 
1               5                   10                  15


Trp Asn Asn Tyr Phe His Leu Ala Val Ala Phe Leu Thr Gln Glu Ser 
            20                  25                  30


Leu Gln Leu Glu Asn Phe Ser Ser Ala Lys Arg Ala Lys Ile Leu Asn 
        35                  40                  45


Lys Tyr Gly Asp Met Arg Arg Gln Ile Gly Phe Glu Ile Arg Asp Met 
    50                  55                  60


Trp Tyr Asn Leu Gly Gln His Lys Ile Lys Phe Ile Pro Glu Met Val 
65                  70                  75                  80


Gly Pro Ile Leu Glu Met Thr Leu Ile Pro Glu Thr Glu Leu Arg Lys 
                85                  90                  95


Ala Thr Ile Pro Ile Phe Phe Asp Met Met Gln Cys Glu Phe His Ser 
            100                 105                 110


Thr Arg Ser Phe Gln Met Phe Glu Asn Glu Ile Ile Thr Lys Leu Asp 
        115                 120                 125


His Glu Val Glu Gly Gly Arg Gly Asp Glu Gln Tyr Lys Val Leu Phe 
    130                 135                 140


Asp Lys Ile Leu Leu Glu His Cys Arg Lys His Lys Tyr Leu Ala Lys 
145                 150                 155                 160


Thr Gly Glu Thr Phe Val Lys Leu Val Val Arg Leu Met Glu Arg Leu 
                165                 170                 175


Leu Asp Tyr Arg Thr Ile Met His Asp Glu Asn Lys Glu Asn Arg Met 
            180                 185                 190


Ser Cys Thr Val Asn Val Leu Asn Phe Tyr Lys Glu Ile Glu Arg Glu 
        195                 200                 205


Glu Met Tyr Ile Arg Tyr Leu Tyr Lys Leu Cys Asp Leu His Lys Glu 
    210                 215                 220


Cys Asp Asn Tyr Thr Glu Ala Ala Tyr Thr Leu Leu Leu His Ala Lys 
225                 230                 235                 240


Leu Leu Lys Trp Ser Glu Asp Val Cys Val Ala His Leu Thr Gln Arg 
                245                 250                 255


Asp Gly Tyr Gln Ala Thr Thr Gln Gly Gln Leu Lys Glu Gln Leu Tyr 
            260                 265                 270


Gln Glu Ile Ile His Tyr Phe Asp Lys Gly Lys Met Trp Glu Glu Ala 
        275                 280                 285


Ile Ala Leu Gly Lys Glu Leu Ala Glu Gln Tyr Glu Asn Glu Met Phe 
    290                 295                 300


Asp Tyr Glu Gln Leu Ser Glu Leu Leu Lys Lys Gln Ala Gln Phe Tyr 
305                 310                 315                 320


Glu Asn Ile Val Lys Val Ile Arg Pro Lys Pro Asp Tyr Phe Ala Val 
                325                 330                 335


Gly Tyr Tyr Gly Gln Gly Phe Pro Thr Phe Leu Arg Gly Lys Val Phe 
            340                 345                 350


Ile Tyr Arg Gly Lys Glu Tyr Glu Arg Arg Glu Asp Phe Glu Ala Arg 
        355                 360                 365


Leu Leu Thr Gln Phe Pro Asn Ala Glu Lys Met Lys Thr Thr Ser Pro 
    370                 375                 380


Pro Gly Asp Asp Ile Lys Asn Ser Pro Gly Gln Tyr Ile Gln Cys Phe 
385                 390                 395                 400


Thr Val Lys Pro Lys Leu Asp Leu Pro Pro Lys Phe His Arg Pro Val 
                405                 410                 415


Ser Glu Gln Ile Val Ser Phe Tyr Arg Val Asn Glu Val Gln Arg Phe 
            420                 425                 430


Glu Tyr Ser Arg Pro Ile Arg Lys Gly Glu Lys Asn Pro Asp Asn Glu 
        435                 440                 445


Phe Ala Asn Met Trp Ile Glu Arg Thr Ile Tyr Thr Thr Ala Tyr Lys 
    450                 455                 460


Leu Pro Gly Ile Leu Arg Trp Phe Glu Val Lys Ser Val Phe Met Val 
465                 470                 475                 480


Glu Ile Ser Pro Leu Glu Asn Ala Ile Glu Thr Met Gln Leu Thr Asn 
                485                 490                 495


Asp Lys Ile Asn Ser Met Val Gln Gln His Leu Asp Asp Pro Ser Leu 
            500                 505                 510


Pro Ile Asn Pro Leu Ser Met Leu Leu Asn Gly Ile Val Asp Pro Ala 
        515                 520                 525


Val Met Gly Gly Phe Ala Asn Tyr Glu Lys Ala Phe Phe Thr Asp Arg 
    530                 535                 540


Tyr Leu Gln Glu His Pro Glu Ala His Glu Lys Ile Glu Lys Leu Lys 
545                 550                 555                 560


Asp Leu Ile Ala Trp Gln Ile Pro Phe Leu Ala Glu Gly Ile Arg Ile 
                565                 570                 575


His Gly Asp Lys Val Thr Glu Ala Leu Arg Pro Phe His Glu Arg Met 
            580                 585                 590


Glu Ala Cys Phe Lys Gln Leu Lys Glu Lys Val Glu Lys Glu Tyr Gly 
        595                 600                 605


Val Arg Ile Met Pro Ser Ser Leu Asp Asp Arg Arg Gly Ser Arg Pro 
    610                 615                 620


Arg Ser Met Val Arg Ser Phe Thr Met Pro Ser Ser Ser Arg Pro Leu 
625                 630                 635                 640


Ser Val Ala Ser Val Ser Ser Leu Ser Ser Asp Ser Thr Pro Ser Arg 
                645                 650                 655


Pro Gly Ser Asp Gly Phe Ala Leu Glu Pro Leu Leu Pro Lys Lys Met 
            660                 665                 670


His Ser Arg Ser Gln Asp Lys Leu Asp Lys Asp Asp Leu Glu Lys Glu 
        675                 680                 685


Lys Lys Asp Lys Lys Lys Glu Lys Arg Asn Ser Lys His Gln Glu Ile 
    690                 695                 700


Phe Glu Lys Glu Phe Lys Pro Thr Asp Ile Ser Leu Gln Gln Ser Glu 
705                 710                 715                 720


Ala Val Ile Leu Ser Glu Thr Ile Ser Pro Leu Arg Pro Gln Arg Pro 
                725                 730                 735


Lys Ser Gln Val Met Asn Val Ile Gly Ser Glu Arg Arg Phe Ser Val 
            740                 745                 750


Ser Pro Ser Ser Pro Ser Ser Gln Gln Thr Pro Pro Pro Val Thr Pro 
        755                 760                 765


Arg Ala Lys Leu Ser Phe Ser Met Gln Ser Ser Leu Glu Leu Asn Gly 
    770                 775                 780


Met Thr Gly Ala Asp Val Ala Asp Val Pro Pro Pro Leu Pro Leu Lys 
785                 790                 795                 800


Gly Ser Val Ala Asp Tyr Gly Asn Leu Met Glu Asn Gln Asp Leu Leu 
                805                 810                 815


Gly Ser Pro Thr Pro Pro Pro Pro Pro Pro His Gln Arg His Leu Pro 
            820                 825                 830


Pro Pro Leu Pro Ser Lys Thr Pro Pro Pro Pro Pro Pro Lys Thr Thr 
        835                 840                 845


Arg Lys Gln Ala Ser Val Asp Ser Gly Ile Val Gln 
    850                 855                 860


<210>  7438
<211>  795
<212>  DNA
<213>  Homo sapiens

<400>  7438
ccttagctca agctctctta aattccttat ggcagaatga aaacaacttc attagggcct     60

acctgagaag aaaacaaaaa caagaaaaag tgtggacatc attatccact tgtcctggct    120

gccttgcccc cttctaacca tttcatgccc attctagtgt gggcttctga gtgctcattt    180

ggtttttcat atagttttta aatcagttgt tactgtcaag atgaaaacat atcacagatg    240

ttagtagcgc agtgctgagt gcttcttaaa cagtattaac ttacatgctt gatgaccatg    300

tgttcttgat taacaaagcc aacgcaagta caaaaaaaaa taaaaattac aagttgttct    360

taaatttaat gacattttgt aagaacccgt aaggcatatt ttaaggccag catattgcat    420

gtgaactctt cctggccctt tctctgtggt gttatgaaat gaatgtcacc cttttcaggg    480

aaaagttttc atttaccgag ggaaagagta tgagcgccgg gaagattttg aggctcggct    540

cttaactcag tttccaaacg ccgagaaaat gaagacaaca tctccaccag gcgacgatat    600

taaaaactct cctggccagt atattcagtg cttcacagtg aagcccaaac tcgatctgcc    660

tcctaagttt cacaggccag tgtcagagca gattgtaagg taataatccc atttttctta    720

cccaacgtga gggttgtaag aggctgtgta cagatctctt gctaataatt ccacctttta    780

aaggacggac tttgg                                                     795


<210>  7439
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  7439

Met Lys Thr Thr Ser Pro Pro Gly Asp Asp Ile Lys Asn Ser Pro Gly 
1               5                   10                  15


Gln Tyr Ile Gln Cys Phe Thr Val Lys Pro Lys Leu Asp Leu Pro Pro 
            20                  25                  30


Lys Phe His Arg Pro Val Ser Glu Gln Ile Val Arg 
        35                  40


<210>  7440
<211>  1570
<212>  DNA
<213>  Homo sapiens

<400>  7440
atacgaggat gctataggtc tccagcatca catctcttta cagggtcccc tgagcattgt     60

gcagatgctg ccattcctcc taggtaaagt ccatggccat atcttcaaag gacaccaacc    120

cctataatgg cttatttctc aagtcattgg gcctgggtca cacagttttc tgggaatttg    180

cccttctgtg tgtgtgtatc ttacatgtag gtatgctcac tgacagcccc caccaagcct    240

ccagccaccc actgccagct accactgagc catcatgcat gccaacccag ctgtgctttc    300

agatgaccca tcatagctgc tgccttactg caccggtggg tgagacaagc cagcctgctg    360

agactcccta agccacagaa acagaagtac tagtaaactg tttgaaactg ctatgtttca    420

ggggtggttt tttaaagcag attagataac aggaacagaa tttggcagct ggaatggggt    480

gctgtggtaa taagaagcta tgacatgcag cactggacct aagactgagc agaagctggg    540

cctcaaggag accgttcatg gaagctggaa gggtgtcaag actcttggcg ctgctgggag    600

gctcagctgg ccccggggcc tgcctgctgt cctgcctgca tggaccacca ggctgagctg    660

cccgctgtcc tgcctgcagg gcccgcctgc cggggctgcc cgctgtgcag cctgcaaggc    720

ccaccttccg gggttgccct ctaagctgcc tacagtgccc gcctgccggg gctgccttcc    780

gggattgccc gctctcctgc ctgcaggccc tgctgggagg ctcagctggc tcagcctgca    840

gggccggcct gccggggctg cccgctgtac gtcctcgagt tccgactgga aggctcagct    900

ggccccaggg ccccatgcgg ggcctctccg ctgtcccgcc ttcagggctc gccagcctcc    960

gctgcccgct gtcctgtctg caggggctgc cttccgggat tgcccgctct cctgcgtgca   1020

ggccctgctg ggaggctcag ctggccccgg ggaccgcctg ccgggtctgc ccgctgtgct   1080

gcctgcatgg accaccagcc tgagctgccc gctctcctgc ctgcaggccc ggctgggagg   1140

ctcagctggc cccggggacc gcctgccgtg tcggcccgct aacctgcctg cagggcccgc   1200

cagcctgagc tgctcgctgt cctgcctgca gggcccgcct gccggggctg cccgctgtgc   1260

agcctgcaag gcccacctgc cggggttgcc ctctaagctg cctacagtgc ccgcctgccg   1320

gtgctgccca ctgtacatct ttcaggccca gctgggaggc tcagctggca ctggggcttg   1380

catgccgggc ctgtctgctg tcctgccttc agagctcgcc agcctgggct gcccgcggtc   1440

ctgtctgcag gggccgcctg ccgggattgc ccgctctcct gctggcaggc ccggctggga   1500

ggctcagctt gtcccgggga ccgcctgccg ggtctgcccg ctgtcctgcc tgcatggacc   1560

accagcctga                                                          1570


<210>  7441
<211>  356
<212>  PRT
<213>  Homo sapiens

<400>  7441

Met Thr Cys Ser Thr Gly Pro Lys Thr Glu Gln Lys Leu Gly Leu Lys 
1               5                   10                  15


Glu Thr Val His Gly Ser Trp Lys Gly Val Lys Thr Leu Gly Ala Ala 
            20                  25                  30


Gly Arg Leu Ser Trp Pro Arg Gly Leu Pro Ala Val Leu Pro Ala Trp 
        35                  40                  45


Thr Thr Arg Leu Ser Cys Pro Leu Ser Cys Leu Gln Gly Pro Pro Ala 
    50                  55                  60


Gly Ala Ala Arg Cys Ala Ala Cys Lys Ala His Leu Pro Gly Leu Pro 
65                  70                  75                  80


Ser Lys Leu Pro Thr Val Pro Ala Cys Arg Gly Cys Leu Pro Gly Leu 
                85                  90                  95


Pro Ala Leu Leu Pro Ala Gly Pro Ala Gly Arg Leu Ser Trp Leu Ser 
            100                 105                 110


Leu Gln Gly Arg Pro Ala Gly Ala Ala Arg Cys Thr Ser Ser Ser Ser 
        115                 120                 125


Asp Trp Lys Ala Gln Leu Ala Pro Gly Pro His Ala Gly Pro Leu Arg 
    130                 135                 140


Cys Pro Ala Phe Arg Ala Arg Gln Pro Pro Leu Pro Ala Val Leu Ser 
145                 150                 155                 160


Ala Gly Ala Ala Phe Arg Asp Cys Pro Leu Ser Cys Val Gln Ala Leu 
                165                 170                 175


Leu Gly Gly Ser Ala Gly Pro Gly Asp Arg Leu Pro Gly Leu Pro Ala 
            180                 185                 190


Val Leu Pro Ala Trp Thr Thr Ser Leu Ser Cys Pro Leu Ser Cys Leu 
        195                 200                 205


Gln Ala Arg Leu Gly Gly Ser Ala Gly Pro Gly Asp Arg Leu Pro Cys 
    210                 215                 220


Arg Pro Ala Asn Leu Pro Ala Gly Pro Ala Ser Leu Ser Cys Ser Leu 
225                 230                 235                 240


Ser Cys Leu Gln Gly Pro Pro Ala Gly Ala Ala Arg Cys Ala Ala Cys 
                245                 250                 255


Lys Ala His Leu Pro Gly Leu Pro Ser Lys Leu Pro Thr Val Pro Ala 
            260                 265                 270


Cys Arg Cys Cys Pro Leu Tyr Ile Phe Gln Ala Gln Leu Gly Gly Ser 
        275                 280                 285


Ala Gly Thr Gly Ala Cys Met Pro Gly Leu Ser Ala Val Leu Pro Ser 
    290                 295                 300


Glu Leu Ala Ser Leu Gly Cys Pro Arg Ser Cys Leu Gln Gly Pro Pro 
305                 310                 315                 320


Ala Gly Ile Ala Arg Ser Pro Ala Gly Arg Pro Gly Trp Glu Ala Gln 
                325                 330                 335


Leu Val Pro Gly Thr Ala Cys Arg Val Cys Pro Leu Ser Cys Leu His 
            340                 345                 350


Gly Pro Pro Ala 
        355


<210>  7442
<211>  1642
<212>  DNA
<213>  Homo sapiens

<400>  7442
atacgaggat gctataggtc tccagcatca catctcttta cagggtcccc tgagcattgt     60

gcagatgctg ccattcctcc taggtaaagt ccatggccat atcttcaaag gacaccaacc    120

cctataatgg cttatttctc aagtcattgg gcctgggtca cacagttttc tgggaatttg    180

cccttctgtg tgtgtgtatc ttacatgtag gtatgctcac tgacagcccc caccaagcct    240

ccagccaccc actgccagct accactgagc catcatgcat gccaacccag ctgtgctttc    300

agatgaccca tcatagctgc tgccttactg caccggtggg tgagacaagc cagcctgctg    360

agactcccta agccacagaa acagaagtac tagtaaactg tttgaaactg ctatgtttca    420

ggggtggttt tttaaagcag attagataac aggaacagaa tttggcagct ggaatggggt    480

gctgtggtaa taagaagcta tgacatgcag cactggacct aagactgagc agaagctggg    540

cctcaaggag accgttcatg gaagctggaa gggtgtcaag actcttggcg ctgctgggag    600

gctcagctgg ccccggggcc tgcctgctgt cctgcctgca tggaccacca ggctgagctg    660

cccgctgtcc tgcctgcagg gcccgcctgc cggggctgcc cgctgtgcag cctgcaaggc    720

ccaccttccg gggttgccct ctaagctgcc tacagtgccc gcctgccggg gctgccttcc    780

gggattgccc gctctcctgc ctgcaggccc tgctgggagg ctcagctggc tcagcctgca    840

gggccggcct gccggggctg cccgctgtac gtcctcgagt tccgactgga aggctcagct    900

ggccccaggg ccccatgcgg ggcctctccg ctgtcccgcc ttcagggctc gccagcctcc    960

gctgcccgct gtcctgtctg caggggctgc cttccgggat tgcccgctct cctgcgtgca   1020

ggccctgctg ggaggctcag ctggccccgg ggaccgcctg ccgggtctgc ccgctgtgct   1080

gcctgcatgg accaccagcc tgagctgccc gctctcctgc ctgcaggccc ggctgggagg   1140

ctcagctggc cccggggacc gcctgccgtg tcggcccgct aacctgcctg cagggcccgc   1200

cagcctgagc tgctcgctgt cctgcctgca gggcccgcct gccggggctg cccgctgtgc   1260

agcctgcaag gcccacctgc cggggttgcc ctctaagctg cctacagtgc ccgcctgccg   1320

agctcgccag cctgggctgc ccgcggtcct gtctgcaggg gccgcctgcc gggattgccc   1380

gctctcctgc tggcaggccc ggctgggagg ctcagcttgt cccggggacc gcctgccggg   1440

tctgcccgct gtcctgcctg catggaccac cagcctgagc tgcccgctgt cctgcctgca   1500

gggcctgcag gcccggctgg gaggctcagc tggccccggg gaccgcctgc cgggtctgcc   1560

cgctctcctg cctgcagggc ccgccagcct gagctgctcg ctgtcctgcc tgcagggccc   1620

gcctgccggg gttgccctct aa                                            1642


<210>  7443
<211>  380
<212>  PRT
<213>  Homo sapiens

<400>  7443

Met Thr Cys Ser Thr Gly Pro Lys Thr Glu Gln Lys Leu Gly Leu Lys 
1               5                   10                  15


Glu Thr Val His Gly Ser Trp Lys Gly Val Lys Thr Leu Gly Ala Ala 
            20                  25                  30


Gly Arg Leu Ser Trp Pro Arg Gly Leu Pro Ala Val Leu Pro Ala Trp 
        35                  40                  45


Thr Thr Arg Leu Ser Cys Pro Leu Ser Cys Leu Gln Gly Pro Pro Ala 
    50                  55                  60


Gly Ala Ala Arg Cys Ala Ala Cys Lys Ala His Leu Pro Gly Leu Pro 
65                  70                  75                  80


Ser Lys Leu Pro Thr Val Pro Ala Cys Arg Gly Cys Leu Pro Gly Leu 
                85                  90                  95


Pro Ala Leu Leu Pro Ala Gly Pro Ala Gly Arg Leu Ser Trp Leu Ser 
            100                 105                 110


Leu Gln Gly Arg Pro Ala Gly Ala Ala Arg Cys Thr Ser Ser Ser Ser 
        115                 120                 125


Asp Trp Lys Ala Gln Leu Ala Pro Gly Pro His Ala Gly Pro Leu Arg 
    130                 135                 140


Cys Pro Ala Phe Arg Ala Arg Gln Pro Pro Leu Pro Ala Val Leu Ser 
145                 150                 155                 160


Ala Gly Ala Ala Phe Arg Asp Cys Pro Leu Ser Cys Val Gln Ala Leu 
                165                 170                 175


Leu Gly Gly Ser Ala Gly Pro Gly Asp Arg Leu Pro Gly Leu Pro Ala 
            180                 185                 190


Val Leu Pro Ala Trp Thr Thr Ser Leu Ser Cys Pro Leu Ser Cys Leu 
        195                 200                 205


Gln Ala Arg Leu Gly Gly Ser Ala Gly Pro Gly Asp Arg Leu Pro Cys 
    210                 215                 220


Arg Pro Ala Asn Leu Pro Ala Gly Pro Ala Ser Leu Ser Cys Ser Leu 
225                 230                 235                 240


Ser Cys Leu Gln Gly Pro Pro Ala Gly Ala Ala Arg Cys Ala Ala Cys 
                245                 250                 255


Lys Ala His Leu Pro Gly Leu Pro Ser Lys Leu Pro Thr Val Pro Ala 
            260                 265                 270


Cys Arg Ala Arg Gln Pro Gly Leu Pro Ala Val Leu Ser Ala Gly Ala 
        275                 280                 285


Ala Cys Arg Asp Cys Pro Leu Ser Cys Trp Gln Ala Arg Leu Gly Gly 
    290                 295                 300


Ser Ala Cys Pro Gly Asp Arg Leu Pro Gly Leu Pro Ala Val Leu Pro 
305                 310                 315                 320


Ala Trp Thr Thr Ser Leu Ser Cys Pro Leu Ser Cys Leu Gln Gly Leu 
                325                 330                 335


Gln Ala Arg Leu Gly Gly Ser Ala Gly Pro Gly Asp Arg Leu Pro Gly 
            340                 345                 350


Leu Pro Ala Leu Leu Pro Ala Gly Pro Ala Ser Leu Ser Cys Ser Leu 
        355                 360                 365


Ser Cys Leu Gln Gly Pro Pro Ala Gly Val Ala Leu 
    370                 375                 380


<210>  7444
<211>  759
<212>  DNA
<213>  Homo sapiens

<400>  7444
ttcctatact tggtaagggg cctgcacggg catagccccc cccagcaaga ctccgcacac     60

accccggcca cccagtcact ggccaatggg ctcctaggaa gatcaaatgt cactataaca    120

cgagggtgtg agccgggcgc cagtgcctgc agccggtgct gtccacaggg agctccagcc    180

cttctcacac tcgacccgca gaaaccaccc accttcacca tgtctgacga ggaagttgaa    240

caggtggagg agcagtacga agaagaagag gaagcccagg aggaagctgc agaagtccat    300

gaggaagttc atgaaccaga ggaagttcaa gaagaggaga aaccgagacc caaactcact    360

gctcctaaga tcccagaagg ggagaaagtg gacttcgatg acatccagaa gaagcgtcag    420

aacaaagacc taatggagct ccaggccctc atcgacagcc actttgaagc ccggaagaag    480

gaggaggagg agctggtcgc tctcaaagag agaatcgaga agcgccgtgc agagagagcg    540

gagcagcaga ggattcgtgc agagaaggag agggagcgcc agaacagact ggcggaggaa    600

aaggccagaa gggaggagga ggatgccaag aggagggcag aggacgacct gaagaagaag    660

aaagctctgt cttccatggg agccaactac agcagctacc tggccaaggc tgaccagaag    720

agaggcaaga agcagacagc ccgggaaatg aagaagaag                           759


<210>  7445
<211>  179
<212>  PRT
<213>  Homo sapiens

<400>  7445

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu 
            20                  25                  30


Pro Glu Glu Val Gln Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala 
        35                  40                  45


Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys 
    50                  55                  60


Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser 
65                  70                  75                  80


His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys 
                85                  90                  95


Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile 
            100                 105                 110


Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys 
        115                 120                 125


Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu 
    130                 135                 140


Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr 
145                 150                 155                 160


Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu 
                165                 170                 175


Met Lys Lys 



<210>  7446
<211>  744
<212>  DNA
<213>  Homo sapiens

<400>  7446
ttcctatact tggtaagggg cctgcacggg catagccccc cccagcaaga ctccgcacac     60

accccggcca cccagtcact ggccaatggg ctcctaggaa gatcaaatgt cactataaca    120

cgagggtgtg agccgggcgc cagtgcctgc agccggtgct gtccacaggg agctccagcc    180

cttctcacac tcgacccgca gaaaccaccc accttcacca tgtctgacga ggaagttgaa    240

caggtggagg agcagtacga agaagaagag gaagcccagg aggaagctgc agaagtccat    300

gaggaagttc atgaaccaga ggagaaaccg agacccaaac tcactgctcc taagatccca    360

gaaggggaga aagtggactt cgatgacatc cagaagaagc gtcagaacaa agacctaatg    420

gagctccagg ccctcatcga cagccacttt gaagcccgga agaaggagga ggaggagctg    480

gtcgctctca aagagagaat cgagaagcgc cgtgcagaga gagcggagca gcagaggatt    540

cgtgcagaga aggagaggga gcgccagaac agactggcgg aggaaaaggc cagaagggag    600

gaggaggatg ccaagaggag ggcagaggac gacctgaaga agaagaaagc tctgtcttcc    660

atgggagcca actacagcag ctacctggcc aaggctgacc agaagagagg caagaagcag    720

acagcccggg aaatgaagaa gaag                                           744


<210>  7447
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  7447

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu 
            20                  25                  30


Pro Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu 
        35                  40                  45


Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys 
    50                  55                  60


Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu Ala Arg 
65                  70                  75                  80


Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu Lys 
                85                  90                  95


Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu 
            100                 105                 110


Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu 
        115                 120                 125


Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala 
    130                 135                 140


Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp 
145                 150                 155                 160


Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys 
                165                 170


<210>  7448
<211>  1207
<212>  DNA
<213>  Homo sapiens

<400>  7448
ttcctatact tggtaagggg cctgcacggg catagccccc cccagcaaga ctccgcacac     60

accccggcca cccagtcact ggccaatggg ctcctaggaa gatcaaatgt cactataaca    120

cgagggtgtg agccgggcgc cagtgcctgc agccggtgct gtccacaggg agctccagcc    180

cttctcacac tcgacccgca gaaaccaccc accttcacca tgtctgacga ggaagttgaa    240

caggtggagg agcagtacga agaagaagag gaagcccagg aggaagctgc agaagtccat    300

gaggaagttc atgaaccaga ggagaaaccg agacccaaac tcactgctcc taagatccca    360

gaaggggaga aagtggactt cgatgacatc cagaagaagc gtcagaacaa agacctaatg    420

gagctccagg ccctcatcga cagccacttt gaagcccgga agaaggagga ggaggagctg    480

gtcgctctca aagagagaat cgagaagcgc cgtgcagaga gagcggagca gcagaggatt    540

cgtgcagaga aggagaggga gcgccagaac agactggcgg aggaaaaggc cagaagggag    600

gaggaggatg ccaagaggag ggcagaggac gacctgaaga agaagaaagc tctgtcttcc    660

atgggagcca actacagcag ctacctggcc aaggctgacc agaagagagg caagaagcag    720

acagcccggg aaatgaagaa gaagattctg gctgagagac gcaagccgct caacatcgat    780

caccttggtg aagacaaact gagggacaag gccaaggagc tctgggagac cctgcaccag    840

ctggagattg acaagttcga gtttggggag aagctgaaac gccagaaata tgacatcacc    900

acgctcagga gccgcattga ccaggcccag aagcacagca agaaggctgg gaccccagcc    960

aagggcaaag tcggcgggcg ctggaagtag agaggccaga aaggcccctc gaggcagaga   1020

ccctccgccc tcttgcacac cagggccgct cgtgggactc cacatcctcc agcccccaca   1080

atcctgtcag gggctccctg acagtcctgg gggtggagag gccatcccgg ggcgtccccc   1140

gcgtctgtgt ccttgctgcc ttcatcccct ggggcctgtg aataaagctg cagaaccccc   1200

ttcacag                                                             1207


<210>  7449
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7449

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu 
            20                  25                  30


Pro Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu 
        35                  40                  45


Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys 
    50                  55                  60


Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu Ala Arg 
65                  70                  75                  80


Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu Lys 
                85                  90                  95


Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu 
            100                 105                 110


Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu 
        115                 120                 125


Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala 
    130                 135                 140


Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp 
145                 150                 155                 160


Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys Lys Ile 
                165                 170                 175


Leu Ala Glu Arg Arg Lys Pro Leu Asn Ile Asp His Leu Gly Glu Asp 
            180                 185                 190


Lys Leu Arg Asp Lys Ala Lys Glu Leu Trp Glu Thr Leu His Gln Leu 
        195                 200                 205


Glu Ile Asp Lys Phe Glu Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr 
    210                 215                 220


Asp Ile Thr Thr Leu Arg Ser Arg Ile Asp Gln Ala Gln Lys His Ser 
225                 230                 235                 240


Lys Lys Ala Gly Thr Pro Ala Lys Gly Lys Val Gly Gly Arg Trp Lys 
                245                 250                 255


<210>  7450
<211>  674
<212>  DNA
<213>  Homo sapiens

<400>  7450
agtcactggc caatgggctc ctaggaagat caaatgtcac tataacacga gggtgtgagc     60

cgggcgccag tgcctgcagc cggtgctgtc cacagggagc tccagccctt ctcacactcg    120

acccgcagaa accacccacc ttcaccatgt ctgacgagga agttgaacag gtggaggagc    180

agtacgaaga agaagaggaa gcccaggagg aagctgcaga agtccatgag gaagaggaag    240

ttcaagaaga ggagaaaccg agacccaaac tcactgctcc taagatccca gaaggggaga    300

aagtggactt cgatgacatc cagaagaagc gtcagaacaa agacctaatg gagctccagg    360

ccctcatcga cagccacttt gaagcccgga agaaggagga ggaggagctg gtcgctctca    420

aagagagaat cgagaagcgc cgtgcagaga gagcggagca gcagaggatt cgtgcagaga    480

aggagaggga gcgccagaac agactggcgg aggaaaaggc cagaagggag gaggaggatg    540

ccaagaggag ggcagaggac gacctgaaga agaagaaagc tctgtcttcc atgggagcca    600

actacagcag ctacctggcc aaggctgacc agaagagagg caagaagcag acagcccggg    660

aaatgaagaa gaag                                                      674


<210>  7451
<211>  175
<212>  PRT
<213>  Homo sapiens

<400>  7451

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Glu Glu Val 
            20                  25                  30


Gln Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile Pro 
        35                  40                  45


Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln Asn 
    50                  55                  60


Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu Ala 
65                  70                  75                  80


Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu 
                85                  90                  95


Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu Lys 
            100                 105                 110


Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg Glu 
        115                 120                 125


Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys Lys 
    130                 135                 140


Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala 
145                 150                 155                 160


Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys 
                165                 170                 175


<210>  7452
<211>  649
<212>  DNA
<213>  Homo sapiens

<400>  7452
actggccaat gggctcctag gaagatcaaa tgtcactata acacgagggt gtgagccggg     60

cgccagtgcc tgcagccggt gctgtccaca gggagctcca gcccttctca cactcgaccc    120

gcagaaacca cccaccttca ccatgtctga cgaggaagtt gaacaggtgg aggagcagta    180

cgaagaagaa gaggaagccc aggaggaaga ggaagttcaa gaagaggaga aaccgagacc    240

caaactcact gctcctaaga tcccagaagg ggagaaagtg gacttcgatg acatccagaa    300

gaagcgtcag aacaaagacc taatggagct ccaggccctc atcgacagcc actttgaagc    360

ccggaagaag gaggaggagg agctggtcgc tctcaaagag agaatcgaga agcgccgtgc    420

agagagagcg gagcagcaga ggattcgtgc agagaaggag agggagcgcc agaacagact    480

ggcggaggaa aaggccagaa gggaggagga ggatgccaag aggagggcag aggacgacct    540

gaagaagaag aaagctctgt cttccatggg agccaactac agcagctacc tggccaaggc    600

tgaccagaag agaggcaaga agcagacagc ccgggaaatg aagaagaag                649


<210>  7453
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  7453

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Glu Glu Lys Pro Arg 
            20                  25                  30


Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe 
        35                  40                  45


Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln 
    50                  55                  60


Ala Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu 
65                  70                  75                  80


Leu Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala 
                85                  90                  95


Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg 
            100                 105                 110


Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg 
        115                 120                 125


Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala 
    130                 135                 140


Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys 
145                 150                 155                 160


Gln Thr Ala Arg Glu Met Lys Lys 
                165


<210>  7454
<211>  628
<212>  DNA
<213>  Homo sapiens

<400>  7454
actggccaat gggctcctag gaagatcaaa tgtcactata acacgagggt gtgagccggg     60

cgccagtgcc tgcagccggt gctgtccaca gggagctcca gcccttctca cactcgaccc    120

gcagaaacca cccaccttca ccatgtctga cgaggaagtt gaacaggtgg aggagcagta    180

cgaagaagaa gttcatgaac cagaggagaa accgagaccc aaactcactg ctcctaagat    240

cccagaaggg gagaaagtgg acttcgatga catccagaag aagcgtcaga acaaagacct    300

aatggagctc caggccctca tcgacagcca ctttgaagcc cggaagaagg aggaggagga    360

gctggtcgct ctcaaagaga gaatcgagaa gcgccgtgca gagagagcgg agcagcagag    420

gattcgtgca gagaaggaga gggagcgcca gaacagactg gcggaggaaa aggccagaag    480

ggaggaggag gatgccaaga ggagggcaga ggacgacctg aagaagaaga aagctctgtc    540

ttccatggga gccaactaca gcagctacct ggccaaggct gaccagaaga gaggcaagaa    600

gcagacagcc cgggaaatga agaagaag                                       628


<210>  7455
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  7455

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Val His Glu Pro Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys 
            20                  25                  30


Ile Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg 
        35                  40                  45


Gln Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe 
    50                  55                  60


Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg 
65                  70                  75                  80


Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala 
                85                  90                  95


Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg 
            100                 105                 110


Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys 
        115                 120                 125


Lys Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala 
    130                 135                 140


Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys 
145                 150                 155                 160


Lys 



<210>  7456
<211>  1111
<212>  DNA
<213>  Homo sapiens

<400>  7456
actggccaat gggctcctag gaagatcaaa tgtcactata acacgagggt gtgagccggg     60

cgccagtgcc tgcagccggt gctgtccaca gggagctcca gcccttctca cactcgaccc    120

gcagaaacca cccaccttca ccatgtctga cgaggaagtt gaacaggtgg aggagcagta    180

cgaagaagaa gaggaagccc aggaggaaga ggaagttcaa gaagaggaga aaccgagacc    240

caaactcact gctcctaaga tcccagaagg ggagaaagtg gacttcgatg acatccagaa    300

gaagcgtcag aacaaagacc taatggagct ccaggccctc atcgacagcc actttgaagc    360

ccggaagaag gaggaggagg agctggtcgc tctcaaagag agaatcgaga agcgccgtgc    420

agagagagcg gagcagcaga ggattcgtgc agagaaggag agggagcgcc agaacagact    480

ggcggaggaa aaggccagaa gggaggagga ggatgccaag aggagggcag aggacgacct    540

gaagaagaag aaagctctgt cttccatggg agccaactac agcagctacc tggccaaggc    600

tgaccagaag agaggcaaga agcagacagc ccgggaaatg aagaagaaga ttctggctga    660

gagacgcaag ccgctcaaca tcgatcacct tggtgaagac aaactgaggg acaaggccaa    720

ggagctctgg gagaccctgc accagctgga gattgacaag ttcgagtttg gggagaagct    780

gaaacgccag aaatatgaca tcatgaatgt ccgggccaga gtgcagatgc tggccaagtt    840

cagcaagaag gctgggaccc cagccaaggg caaagtcggc gggcgctgga agtagagagg    900

ccagaaaggc ccctcgaggc agagaccctc cgccctcttg cacaccaggg ccgctcgtgg    960

gactccacat cctccagccc ccacaatcct gtcaggggct ccctgacagt cctgggggtg   1020

gagaggccat cccggggcgt cccccgcgtc tgtgtccttg ctgccttcat cccctggggc   1080

ctgtgaataa agctgcagaa cccccttcac a                                  1111


<210>  7457
<211>  250
<212>  PRT
<213>  Homo sapiens

<400>  7457

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Glu Glu Lys Pro Arg 
            20                  25                  30


Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe 
        35                  40                  45


Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln 
    50                  55                  60


Ala Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu 
65                  70                  75                  80


Leu Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala 
                85                  90                  95


Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg 
            100                 105                 110


Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg 
        115                 120                 125


Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala 
    130                 135                 140


Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys 
145                 150                 155                 160


Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu Arg Arg Lys 
                165                 170                 175


Pro Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg Asp Lys Ala 
            180                 185                 190


Lys Glu Leu Trp Glu Thr Leu His Gln Leu Glu Ile Asp Lys Phe Glu 
        195                 200                 205


Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr Asp Ile Met Asn Val Arg 
    210                 215                 220


Ala Arg Val Gln Met Leu Ala Lys Phe Ser Lys Lys Ala Gly Thr Pro 
225                 230                 235                 240


Ala Lys Gly Lys Val Gly Gly Arg Trp Lys 
                245                 250


<210>  7458
<211>  582
<212>  DNA
<213>  Homo sapiens

<400>  7458
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttccca atgcagagca gtacgaagaa    120

gaagaggaag cccaggagga agaggaagtt caagaagagg agaaaccgag acccaaactc    180

actgctccta agatcccaga aggggagaaa gtggacttcg atgacatcca gaagaagcgt    240

cagaacaaag acctaatgga gctccaggcc ctcatcgaca gccactttga agcccggaag    300

aaggaggagg aggagctggt cgctctcaaa gagagaatcg agaagcgccg tgcagagaga    360

gcggagcagc agaggattcg tgcagagaag gagagggagc gccagaacag actggcggag    420

gaaaaggcca gaagggagga ggaggatgcc aagaggaggg cagaggacga cctgaagaag    480

aagaaagctc tgtcttccat gggagccaac tacagcagct acctggccaa ggctgaccag    540

aagagaggca agaagcagac agcccgggaa atgaagaaga ag                       582


<210>  7459
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7459

Met Ser Asp Glu Glu Val Pro Asn Ala Glu Gln Tyr Glu Glu Glu Glu 
1               5                   10                  15


Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Glu Glu Lys Pro Arg Pro 
            20                  25                  30


Lys Leu Thr Ala Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp 
        35                  40                  45


Asp Ile Gln Lys Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala 
    50                  55                  60


Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu 
65                  70                  75                  80


Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu 
                85                  90                  95


Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu 
            100                 105                 110


Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala 
        115                 120                 125


Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn 
    130                 135                 140


Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln 
145                 150                 155                 160


Thr Ala Arg Glu Met Lys Lys 
                165


<210>  7460
<211>  603
<212>  DNA
<213>  Homo sapiens

<400>  7460
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttccca atgcagagca gtacgaagaa    120

gaagaggaag cccaggagga agctgcagaa gtccatgagg aagaggaagt tcaagaagag    180

gagaaaccga gacccaaact cactgctcct aagatcccag aaggggagaa agtggacttc    240

gatgacatcc agaagaagcg tcagaacaaa gacctaatgg agctccaggc cctcatcgac    300

agccactttg aagcccggaa gaaggaggag gaggagctgg tcgctctcaa agagagaatc    360

gagaagcgcc gtgcagagag agcggagcag cagaggattc gtgcagagaa ggagagggag    420

cgccagaaca gactggcgga ggaaaaggcc agaagggagg aggaggatgc caagaggagg    480

gcagaggacg acctgaagaa gaagaaagct ctgtcttcca tgggagccaa ctacagcagc    540

tacctggcca aggctgacca gaagagaggc aagaagcaga cagcccggga aatgaagaag    600

aag                                                                  603


<210>  7461
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  7461

Met Ser Asp Glu Glu Val Pro Asn Ala Glu Gln Tyr Glu Glu Glu Glu 
1               5                   10                  15


Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Glu Glu Val Gln 
            20                  25                  30


Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu 
        35                  40                  45


Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys 
    50                  55                  60


Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu Ala Arg 
65                  70                  75                  80


Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu Lys 
                85                  90                  95


Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu 
            100                 105                 110


Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu 
        115                 120                 125


Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala 
    130                 135                 140


Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp 
145                 150                 155                 160


Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys 
                165                 170


<210>  7462
<211>  582
<212>  DNA
<213>  Homo sapiens

<400>  7462
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttgaac aggtggagga gcagtacgaa    120

gaagaagagg aagcccagga ggaagttcat gaaccagagg agaaaccgag acccaaactc    180

actgctccta agatcccaga aggggagaaa gtggacttcg atgacatcca gaagaagcgt    240

cagaacaaag acctaatgga gctccaggcc ctcatcgaca gccactttga agcccggaag    300

aaggaggagg aggagctggt cgctctcaaa gagagaatcg agaagcgccg tgcagagaga    360

gcggagcagc agaggattcg tgcagagaag gagagggagc gccagaacag actggcggag    420

gaaaaggcca gaagggagga ggaggatgcc aagaggaggg cagaggacga cctgaagaag    480

aagaaagctc tgtcttccat gggagccaac tacagcagct acctggccaa ggctgaccag    540

aagagaggca agaagcagac agcccgggaa atgaagaaga ag                       582


<210>  7463
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7463

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Val His Glu Pro Glu Glu Lys Pro Arg Pro 
            20                  25                  30


Lys Leu Thr Ala Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp 
        35                  40                  45


Asp Ile Gln Lys Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala 
    50                  55                  60


Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu 
65                  70                  75                  80


Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu 
                85                  90                  95


Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu 
            100                 105                 110


Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala 
        115                 120                 125


Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn 
    130                 135                 140


Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln 
145                 150                 155                 160


Thr Ala Arg Glu Met Lys Lys 
                165


<210>  7464
<211>  609
<212>  DNA
<213>  Homo sapiens

<400>  7464
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttgaac aggtggagga gcagtacgaa    120

gaagaagagg aagcccagga ggaagaggaa gttcaagaag acaccgcaga ggaggacgcg    180

gaagaggaga aaccgagacc caaactcact gctcctaaga tcccagaagg ggagaaagtg    240

gacttcgatg acatccagaa gaagcgtcag aacaaagacc taatggagct ccaggccctc    300

atcgacagcc actttgaagc ccggaagaag gaggaggagg agctggtcgc tctcaaagag    360

agaatcgaga agcgccgtgc agagagagcg gagcagcaga ggattcgtgc agagaaggag    420

agggagcgcc agaacagact ggcggaggaa aaggccagaa gggaggagga ggatgccaag    480

aggagggcag aggacgacct gaagaagaag aaagctctgt cttccatggg agccaactac    540

agcagctacc tggccaaggc tgaccagaag agaggcaaga agcagacagc ccgggaaatg    600

aagaagaag                                                            609


<210>  7465
<211>  176
<212>  PRT
<213>  Homo sapiens

<400>  7465

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Asp Thr Ala Glu Glu 
            20                  25                  30


Asp Ala Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile 
        35                  40                  45


Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln 
    50                  55                  60


Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu 
65                  70                  75                  80


Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile 
                85                  90                  95


Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu 
            100                 105                 110


Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg 
        115                 120                 125


Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys 
    130                 135                 140


Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys 
145                 150                 155                 160


Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys 
                165                 170                 175


<210>  7466
<211>  577
<212>  DNA
<213>  Homo sapiens

<400>  7466
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttgaac aggtggagga gcagtacgaa    120

gaagaagagg aagcccagga ggaagaggag aaaccgagac ccaaactcac tgctcctaag    180

atcccagaag gggagaaagt ggacttcgat gacatccaga agaagcgtca gaacaaagac    240

ctaatggagc tccaggccct catcgacagc cactttgaag cccggaagaa ggaggaggag    300

gagctggtcg ctctcaaaga gagaatcgag aagcgccgtg cagagagagc ggagcagcag    360

aggattcgtg cagagaagga gagggagcgc cagaacagac tggcggagga aaaggccaga    420

agggaggagg aggatgccaa gaggagggca gaggacgacc tgaagaagaa gaaagctctg    480

tcttccatgg gagccaacta cagcagctac ctggccaagg ctgaccagaa gagaggcaag    540

aagcagacag cccgggaaat gaagaagaag attctgg                             577


<210>  7467
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  7467

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala 
            20                  25                  30


Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys 
        35                  40                  45


Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser 
    50                  55                  60


His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys 
65                  70                  75                  80


Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile 
                85                  90                  95


Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys 
            100                 105                 110


Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu 
        115                 120                 125


Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr 
    130                 135                 140


Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu 
145                 150                 155                 160


Met Lys Lys Lys Ile 
                165


<210>  7468
<211>  565
<212>  DNA
<213>  Homo sapiens

<400>  7468
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttccca atgcagagca gtacgaagaa    120

gaagaggaag cccaggagga agctgcagaa gtccatgagg aagttcatga accagaggaa    180

gttcaagaag aggagaaacc gagacccaaa ctcactgctc ctaagatccc agaaggggag    240

aaagtggact tcgatgacat ccagaagaag cgtcagaaca aagacctaat ggagctccag    300

gccctcatcg acagccactt tgaagccaga agggaggagg aggatgccaa gaggagggca    360

gaggacgacc tgaagaagaa gaaagctctg tcttccatgg gagccaacta cagcagctac    420

ctggccaagg ctgaccagaa gagaggcaag aagcagacag cccgggaaat gaagaagaag    480

attctggctg agagacgcaa gccgctcaac atcgatcacc ttggtgaaga caaactgagg    540

gacaaggcca aggagctctg ggaga                                          565


<210>  7469
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  7469

Met Ser Asp Glu Glu Val Pro Asn Ala Glu Gln Tyr Glu Glu Glu Glu 
1               5                   10                  15


Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu Pro 
            20                  25                  30


Glu Glu Val Gln Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro 
        35                  40                  45


Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys 
    50                  55                  60


Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His 
65                  70                  75                  80


Phe Glu Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp 
                85                  90                  95


Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser 
            100                 105                 110


Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala 
        115                 120                 125


Arg Glu Met Lys Lys Lys Ile Leu Ala Glu Arg Arg Lys Pro Leu Asn 
    130                 135                 140


Ile Asp His Leu Gly Glu Asp Lys Leu Arg Asp Lys Ala Lys Glu Leu 
145                 150                 155                 160


Trp 



<210>  7470
<211>  749
<212>  DNA
<213>  Homo sapiens

<400>  7470
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagtgtgag tacccagctg gtggaggaag    120

cccaggagga agaggaagtt caagaagagg agaaaccgag acccaaactc actgctccta    180

agatcccaga aggggagaaa gtggacttcg atgacatcca gaagaagcgt cagaacaaag    240

acctaatgga gctccaggcc ctcatcgaca gccactttga agcccggaag aaggaggagg    300

aggagctggt cgctctcaaa gagagaatcg agaagcgccg tgcagagaga gcggagcagc    360

agaggattcg tgcagagaag gagagggagc gccagaacag actggcggag gaaaaggcca    420

gaagggagga ggaggatgcc aagaggaggg cagaggacga cctgaagaag aagaaagctc    480

tgtcttccat gggagccaac tacagcagct acctggccaa ggctgaccag aagagaggca    540

agaagcagac agcccgggaa atgaagaaga agattctggc tgagagacgc aaggccgctc    600

gtgggactcc acatcctcca gcccccacaa tcctgtcagg ggctccctga cagtcctggg    660

ggtggagagg ccatcccggg gcgtcccccg cgtctgtgtc cttgctgcct tcatcccctg    720

gggcctgtga ataaagctgc agaaccccc                                      749


<210>  7471
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  7471

Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys 
1               5                   10                  15


Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg 
            20                  25                  30


Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu 
        35                  40                  45


Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp 
    50                  55                  60


Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser 
65                  70                  75                  80


Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys 
                85                  90                  95


Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala 
            100                 105                 110


Glu Arg Arg Lys Ala Ala Arg Gly Thr Pro His Pro Pro Ala Pro Thr 
        115                 120                 125


Ile Leu Ser Gly Ala Pro 
    130


<210>  7472
<211>  508
<212>  DNA
<213>  Homo sapiens

<400>  7472
agtgcctgca gccggtgctg tccacaggga gctccagccc ttctcacact cgacccgcag     60

aaaccaccca ccttcaccat gtctgacgag gaagttccca atgcagagca gtacgaagaa    120

gaagaggaag cccaggagga agctgcagaa gtccatgagg aagttcatga accagaggac    180

gacctgaaga agaagaaagc tctgtcttcc atgggagcca actacagcag ctacctggcc    240

aaggctgacc agaagagagg caagaagcag acagcccggg aaatgaagaa gaagattctg    300

gctgagagac gcaagccgct caacatcgat caccttggtg aagacaaact gagggacaag    360

gccaaggagc tctgggagac cccccacaat cctgtcaggg gctccctgac agtcctgggg    420

gtggagaggc catcccgggg cgtcccccgc gtctgtgtcc ttgctgcctt catcccctgg    480

ggcctgtgaa taaagctgca gaaccccc                                       508


<210>  7473
<211>  136
<212>  PRT
<213>  Homo sapiens

<400>  7473

Met Ser Asp Glu Glu Val Pro Asn Ala Glu Gln Tyr Glu Glu Glu Glu 
1               5                   10                  15


Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu Pro 
            20                  25                  30


Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn 
        35                  40                  45


Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln 
    50                  55                  60


Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu Arg Arg Lys Pro 
65                  70                  75                  80


Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg Asp Lys Ala Lys 
                85                  90                  95


Glu Leu Trp Glu Thr Pro His Asn Pro Val Arg Gly Ser Leu Thr Val 
            100                 105                 110


Leu Gly Val Glu Arg Pro Ser Arg Gly Val Pro Arg Val Cys Val Leu 
        115                 120                 125


Ala Ala Phe Ile Pro Trp Gly Leu 
    130                 135


<210>  7474
<211>  613
<212>  DNA
<213>  Homo sapiens

<400>  7474
tgcctgcagc cggtgctgtc cacagggagc tccagccctt ctcacactcg acccgcagaa     60

accacccacc ttcaccatgt ctgacgagga agttcccaat gcagagcagt acgaagaaga    120

agaggaagcc caggaggaag ctgcagaagt ccatgaggaa gttcatgaac cagaggaagt    180

tcaagaagag gagaaaccga gacccaaact cactgctcct aagatcccag aaggggagaa    240

agtggacttc gatgacatcc agaagaagcg tcagaacaaa gacctaatgg agctccaggc    300

cctcatcgac agccactttg aagcccggaa gaaggaggag gaggagctgg tcgctctcaa    360

agagagaatc gagaagcgcc gtgcagagag agcggagcag cagaggattc gtgcagagaa    420

ggagagggag cgccagaaca gactggcgga ggaaaaggcc agaagggagg aggaggatgc    480

caagaggagg gcagaggacg acctgaagaa gaagaaagct ctgtcttcca tgggagccaa    540

ctacagcagc tacctggcca aggctgacca gaagagaggc aagaagcaga cagcccggga    600

aatgaagaag aag                                                       613


<210>  7475
<211>  178
<212>  PRT
<213>  Homo sapiens

<400>  7475

Met Ser Asp Glu Glu Val Pro Asn Ala Glu Gln Tyr Glu Glu Glu Glu 
1               5                   10                  15


Glu Ala Gln Glu Glu Ala Ala Glu Val His Glu Glu Val His Glu Pro 
            20                  25                  30


Glu Glu Val Gln Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro 
        35                  40                  45


Lys Ile Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys 
    50                  55                  60


Arg Gln Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His 
65                  70                  75                  80


Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu 
                85                  90                  95


Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg 
            100                 105                 110


Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala 
        115                 120                 125


Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys 
    130                 135                 140


Lys Lys Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu 
145                 150                 155                 160


Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met 
                165                 170                 175


Lys Lys 



<210>  7476
<211>  1246
<212>  DNA
<213>  Homo sapiens

<400>  7476
cagaggatgg ccctagagga gtctgtggcg tttggggcct gaaccagctg ggaggacagc     60

acgaggggct ggtgggcagc ctgggactgg gtcacaccgg gggcctggac aacactggct    120

cgtggggctg aggactgagg agagcctggc ccagccgtgg cagttacaag aggcttaacc    180

tgaggggcag cagagtctca ggaagagatt ctgggatagg aaaaagctac ccccgttgcc    240

tggaagacag ctatctgctg gaaaccaccc accttcacca tgtctgacga ggaagttgaa    300

caggtggagg agcagtacga agaagaagag gaagcccagg aggaagagga agttcaagaa    360

gaggagaaac cgagacccaa actcactgct cctaagatcc cagaagggga gaaagtggac    420

ttcgatgaca tccagaagaa gcgtcagaac aaagacctaa tggagctcca ggccctcatc    480

gacagccact ttgaagcccg gaagaaggag gaggaggagc tggtcgctct caaagagaga    540

atcgagaagc gccgtgcaga gagagcggag cagcagagga ttcgtgcaga gaaggagagg    600

gagcgccaga acagactggc ggaggaaaag gccagaaggg aggaggagga tgccaagagg    660

agggcagagg acgacctgaa gaagaagaaa gctctgtctt ccatgggagc caactacagc    720

agctacctgg ccaaggctga ccagaagaga ggcaagaagc agacagcccg ggaaatgaag    780

aagaagattc tggctgagag acgcaagccg ctcaacatcg atcaccttgg tgaagacaaa    840

ctgagggaca aggccaagga gctctgggag accctgcacc agctggagat tgacaagttc    900

gagtttgggg agaagctgaa acgccagaaa tatgacatca ccacgctcag gagccgcatt    960

gaccaggccc agaagcacag caagaaggct gggaccccag ccaagggcaa agtcggcggg   1020

cgctggaagt agagaggcca gaaaggcccc tcgaggcaga gaccctccgc cctcttgcac   1080

accagggccg ctcgtgggac tccacatcct ccagccccca caatcctgtc aggggctccc   1140

tgacagtcct gggggtggag aggccatccc ggggcgtccc ccgcgtctgt gtccttgctg   1200

ccttcatccc ctggggcctg tgaataaagc tgcagaaccc ccttca                  1246


<210>  7477
<211>  250
<212>  PRT
<213>  Homo sapiens

<400>  7477

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Glu Glu Lys Pro Arg 
            20                  25                  30


Pro Lys Leu Thr Ala Pro Lys Ile Pro Glu Gly Glu Lys Val Asp Phe 
        35                  40                  45


Asp Asp Ile Gln Lys Lys Arg Gln Asn Lys Asp Leu Met Glu Leu Gln 
    50                  55                  60


Ala Leu Ile Asp Ser His Phe Glu Ala Arg Lys Lys Glu Glu Glu Glu 
65                  70                  75                  80


Leu Val Ala Leu Lys Glu Arg Ile Glu Lys Arg Arg Ala Glu Arg Ala 
                85                  90                  95


Glu Gln Gln Arg Ile Arg Ala Glu Lys Glu Arg Glu Arg Gln Asn Arg 
            100                 105                 110


Leu Ala Glu Glu Lys Ala Arg Arg Glu Glu Glu Asp Ala Lys Arg Arg 
        115                 120                 125


Ala Glu Asp Asp Leu Lys Lys Lys Lys Ala Leu Ser Ser Met Gly Ala 
    130                 135                 140


Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg Gly Lys Lys 
145                 150                 155                 160


Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu Arg Arg Lys 
                165                 170                 175


Pro Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg Asp Lys Ala 
            180                 185                 190


Lys Glu Leu Trp Glu Thr Leu His Gln Leu Glu Ile Asp Lys Phe Glu 
        195                 200                 205


Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr Asp Ile Thr Thr Leu Arg 
    210                 215                 220


Ser Arg Ile Asp Gln Ala Gln Lys His Ser Lys Lys Ala Gly Thr Pro 
225                 230                 235                 240


Ala Lys Gly Lys Val Gly Gly Arg Trp Lys 
                245                 250


<210>  7478
<211>  1003
<212>  DNA
<213>  Homo sapiens

<400>  7478
cccaccttca ccatgtctga cgaggaagtt gaacaggtgg aggagcagta cgaagaagaa     60

gaggaagccc aggaggaaga ggaagttcaa gaagacaccg cagaggagga cgcggaagag    120

gagaaaccga gacccaaact cactgctcct aagatcccag aaggggagaa agtggacttc    180

gatgacatcc agaagaagcg tcagaacaaa gacctaatgg agctccaggc cctcatcgac    240

agccactttg aagcccggaa gaaggaggag gaggagctgg tcgctctcaa agagagaatc    300

gagaagcgcc gtgcagagag agcggagcag cagaggattc gtgcagagaa ggagagggag    360

cgccagaaca gactggcgga ggaaaaggcc agaagggagg aggaggatgc caagaggagg    420

gcagaggacg acctgaagaa gaagaaagct ctgtcttcca tgggagccaa ctacagcagc    480

tacctggcca aggctgacca gaagagaggc aagaagcaga cagcccggga aatgaagaag    540

aagattctgg ctgagagacg caagccgctc aacatcgatc accttggtga agacaaactg    600

agggacaagg ccaaggagct ctgggagacc ctgcaccagc tggagattga caagttcgag    660

tttggggaga agctgaaacg ccagaaatat gacatcacca cgctcaggag ccgcattgac    720

caggcccaga agcacagcaa gaaggctggg accccagcca agggcaaagt cggcgggcgc    780

tggaagtaga gaggccagaa aggcccctcg aggcagagac cctccgccct cttgcacacc    840

agggccgctc gtgggactcc acatcctcca gcccccacaa tcctgtcagg ggctccctga    900

cagtcctggg ggtggagagg ccatcccggg gcgtcccccg cgtctgtgtc cttgctgcct    960

tcatcccctg gggcctgtga ataaagctgc agaaccccct tca                     1003


<210>  7479
<211>  258
<212>  PRT
<213>  Homo sapiens

<400>  7479

Met Ser Asp Glu Glu Val Glu Gln Val Glu Glu Gln Tyr Glu Glu Glu 
1               5                   10                  15


Glu Glu Ala Gln Glu Glu Glu Glu Val Gln Glu Asp Thr Ala Glu Glu 
            20                  25                  30


Asp Ala Glu Glu Glu Lys Pro Arg Pro Lys Leu Thr Ala Pro Lys Ile 
        35                  40                  45


Pro Glu Gly Glu Lys Val Asp Phe Asp Asp Ile Gln Lys Lys Arg Gln 
    50                  55                  60


Asn Lys Asp Leu Met Glu Leu Gln Ala Leu Ile Asp Ser His Phe Glu 
65                  70                  75                  80


Ala Arg Lys Lys Glu Glu Glu Glu Leu Val Ala Leu Lys Glu Arg Ile 
                85                  90                  95


Glu Lys Arg Arg Ala Glu Arg Ala Glu Gln Gln Arg Ile Arg Ala Glu 
            100                 105                 110


Lys Glu Arg Glu Arg Gln Asn Arg Leu Ala Glu Glu Lys Ala Arg Arg 
        115                 120                 125


Glu Glu Glu Asp Ala Lys Arg Arg Ala Glu Asp Asp Leu Lys Lys Lys 
    130                 135                 140


Lys Ala Leu Ser Ser Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys 
145                 150                 155                 160


Ala Asp Gln Lys Arg Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys 
                165                 170                 175


Lys Ile Leu Ala Glu Arg Arg Lys Pro Leu Asn Ile Asp His Leu Gly 
            180                 185                 190


Glu Asp Lys Leu Arg Asp Lys Ala Lys Glu Leu Trp Glu Thr Leu His 
        195                 200                 205


Gln Leu Glu Ile Asp Lys Phe Glu Phe Gly Glu Lys Leu Lys Arg Gln 
    210                 215                 220


Lys Tyr Asp Ile Thr Thr Leu Arg Ser Arg Ile Asp Gln Ala Gln Lys 
225                 230                 235                 240


His Ser Lys Lys Ala Gly Thr Pro Ala Lys Gly Lys Val Gly Gly Arg 
                245                 250                 255


Trp Lys 



<210>  7480
<211>  1227
<212>  DNA
<213>  Homo sapiens

<400>  7480
tggactccct cggaggagcc ggggacaggg ctgagcagac ccccttctct ggctgcagga     60

gaagcgccgt gcagagagag cggagcagca gaggattcgt gcagagaagg agagggagcg    120

ccagaacaga ctggcggagg aaaaggccag aagggaggag gaggatgcca agaggagggc    180

agaggacgac ctgaagaaga agaaagctct gtcttccatg ggagccaact acagcagcta    240

cctggccaag gctgaccaga agagaggcaa gaagcagaca gcccgggaaa tgaagaagaa    300

gattctggct gagagacgca agccgctcaa catcgatcac cttggtgaag acaaactgag    360

ggacaaggcc aaggagctct gggagaccct gcaccagctg gagattgaca agttcgagtt    420

tggggagaag ctgaaacgcc agaaatatga cgtgagtccc ggcacctccg gccctggggc    480

cctagcggct ttcacccacc agcagagcag ccatctccct gcgtccctac caaactctgg    540

acctgcccac cccagggacc tggaccctga gaggcccaaa caggctgttg ccacggaccc    600

ctggctgagg ctgctttcct gctggggact gtggccagag cccgtcctcc tggctggcca    660

tgcagcgccc tgagcgatga acctggcccc tttgggcggc cttggttacc cctgccaaaa    720

ggactgtcgt ggcagagcag ccatggccaa gtggactcag ggttcatttt cggaacccct    780

ttaagcttat agaaagtccc catcatcacc cagctcggcc ccggggcacc gagtccgtct    840

ggtgtggggc gtcctttcga cagagcctcc tccacaaacc cagactctgg cttccaccag    900

ggccccggac acctgcttcc tcagggcaga cagagagggg tgacacactg caccctgtgg    960

ctgggaaaag gggcctggga ctgtgcccgt ctgggacgga gcagagccac catcccatgc   1020

aggcactatc accgcaggca aagctgggac tggggaaggc agcctgcccg ggcggcctca   1080

gggactgggg tacaatgtgg gagctagggt ggaagccaag ctgcttccca ccctcccaaa   1140

cacccgtttg ggctccaggg gcgaggggtg aggggcgcag ccatgggtga tccacgtgct   1200

cggggcaaat gcagacactc cagcatc                                       1227


<210>  7481
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  7481

Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg 
1               5                   10                  15


Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu 
            20                  25                  30


Arg Arg Lys Pro Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg 
        35                  40                  45


Asp Lys Ala Lys Glu Leu Trp Glu Thr Leu His Gln Leu Glu Ile Asp 
    50                  55                  60


Lys Phe Glu Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr Asp Val Ser 
65                  70                  75                  80


Pro Gly Thr Ser Gly Pro Gly Ala Leu Ala Ala Phe Thr His Gln Gln 
                85                  90                  95


Ser Ser His Leu Pro Ala Ser Leu Pro Asn Ser Gly Pro Ala His Pro 
            100                 105                 110


Arg Asp Leu Asp Pro Glu Arg Pro Lys Gln Ala Val Ala Thr Asp Pro 
        115                 120                 125


Trp Leu Arg Leu Leu Ser Cys Trp Gly Leu Trp Pro Glu Pro Val Leu 
    130                 135                 140


Leu Ala Gly His Ala Ala Pro 
145                 150


<210>  7482
<211>  611
<212>  DNA
<213>  Homo sapiens

<400>  7482
aagggaggag gaggatgcca agaggagggc agaggacgac ctgaagaaga agaaagctct     60

gtcttccatg ggagccaact acagcagcta cctggccaag gctgaccaga agagaggcaa    120

gaagcagaca gcccgggaaa tgaagaagaa gattctggct gagagacgca agccgctcaa    180

catcgatcac cttggtgaag acaaactgag ggacaaggcc aaggagctct gggagaccct    240

gcaccagctg gagattgaca agttcgagtt tggggagaag ctgaaacgcc agaaatatga    300

catcaccacg ctcaggagcc gcattgacca ggcccagaag cacagcaaga aggctgggac    360

cccagccaag ggcaaagtcg gcgggcgctg gaagtagaga ggccagaaag gcccctcgag    420

gcagagaccc tccgccctct tgcacaccag ggccgctcgt gggactccac atcctccagc    480

ccccacaatc ctgtcagggg ctccctgaca gtcctggggg tggagaggcc atcccggggc    540

gtcccccgcg tctgtgtcct tgctgccttc atcccctggg gcctgtgaat aaagctgcag    600

aacccccttc a                                                         611


<210>  7483
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  7483

Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg 
1               5                   10                  15


Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu 
            20                  25                  30


Arg Arg Lys Pro Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg 
        35                  40                  45


Asp Lys Ala Lys Glu Leu Trp Glu Thr Leu His Gln Leu Glu Ile Asp 
    50                  55                  60


Lys Phe Glu Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr Asp Ile Thr 
65                  70                  75                  80


Thr Leu Arg Ser Arg Ile Asp Gln Ala Gln Lys His Ser Lys Lys Ala 
                85                  90                  95


Gly Thr Pro Ala Lys Gly Lys Val Gly Gly Arg Trp Lys 
            100                 105


<210>  7484
<211>  449
<212>  DNA
<213>  Homo sapiens

<400>  7484
agggcagagg acgacctgaa gaagaagaaa gctctgtctt ccatgggagc caactacagc     60

agctacctgg ccaaggctga ccagaagaga ggcaagaagc agacagcccg ggaaatgaag    120

aagaagattc tggctgagag acgcaagccg ctcaacatcg atcaccttgg tgaagacaaa    180

ctgagggaca aggccaagga gctctgggag accctgcacc agctggagat tgacaagttc    240

gagtttgggg agaagctgaa acgccagaaa tatgacatca ccacgctcag gaggccgctc    300

gtgggactcc acatcctcca gcccccacaa tcctgtcagg ggctccctga cagtcctggg    360

ggtggagagg ccatcccggg gcgtcccccg cgtctgtgtc cttgctgcct tcatcccctg    420

gggcctgtga ataaagctgc agaaccccc                                      449


<210>  7485
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  7485

Met Gly Ala Asn Tyr Ser Ser Tyr Leu Ala Lys Ala Asp Gln Lys Arg 
1               5                   10                  15


Gly Lys Lys Gln Thr Ala Arg Glu Met Lys Lys Lys Ile Leu Ala Glu 
            20                  25                  30


Arg Arg Lys Pro Leu Asn Ile Asp His Leu Gly Glu Asp Lys Leu Arg 
        35                  40                  45


Asp Lys Ala Lys Glu Leu Trp Glu Thr Leu His Gln Leu Glu Ile Asp 
    50                  55                  60


Lys Phe Glu Phe Gly Glu Lys Leu Lys Arg Gln Lys Tyr Asp Ile Thr 
65                  70                  75                  80


Thr Leu Arg Arg Pro Leu Val Gly Leu His Ile Leu Gln Pro Pro Gln 
                85                  90                  95


Ser Cys Gln Gly Leu Pro Asp Ser Pro Gly Gly Gly Glu Ala Ile Pro 
            100                 105                 110


Gly Arg Pro Pro Arg Leu Cys Pro Cys Cys Leu His Pro Leu Gly Pro 
        115                 120                 125


Val Asn Lys Ala Ala Glu 
    130


<210>  7486
<211>  338
<212>  DNA
<213>  Homo sapiens

<400>  7486
agggagggtg ccccgggctc acgtgccagc cccctaacca cactaacgac ctaggcccgc     60

caggcacagc agcaagaagg ctgggacccc agccaagggc aaagtcggcg ggcgctggaa    120

gtagagaggc cagaaaggcc cctcgaggca gagaccctcc gccctcttgc acaccagggc    180

cgctcgtggg actccacatc ctccagcccc cacaatcctg tcaggggctc cctgacagtc    240

ctgggggtgg agaggccatc ccggggcgtc ccccgcgtct gtgtccttgc tgccttcatc    300

ccctggggcc tgtgaataaa gctgcagaac ccccttca                            338


<210>  7487
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  7487

Gly Gly Cys Pro Gly Leu Thr Cys Gln Pro Pro Asn His Thr Asn Asp 
1               5                   10                  15


Leu Gly Pro Pro Gly Thr Ala Ala Arg Arg Leu Gly Pro Gln Pro Arg 
            20                  25                  30


Ala Lys Ser Ala Gly Ala Gly Ser Arg Glu Ala Arg Lys Ala Pro Arg 
        35                  40                  45


Gly Arg Asp Pro Pro Pro Ser Cys Thr Pro Gly Pro Leu Val Gly Leu 
    50                  55                  60


His Ile Leu Gln Pro Pro Gln Ser Cys Gln Gly Leu Pro Asp Ser Pro 
65                  70                  75                  80


Gly Gly Gly Glu Ala Ile Pro Gly Arg Pro Pro Arg Leu Cys Pro Cys 
                85                  90                  95


Cys Leu His Pro Leu Gly Pro Val Asn Lys Ala Ala Glu Pro Pro 
            100                 105                 110


<210>  7488
<211>  907
<212>  DNA
<213>  Homo sapiens

<400>  7488
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg gtgcgtgtga gctggccagc cccagcgggg cctccgaggg    480

gctcctcgca actgtgtcct tggggatgtt tgtgccggag acgctgcgct ggggcccagg    540

gagcccccgt gaggccggat ctcagggcct cagcgcagag gcaggctcca cataaggtca    600

tgctccgtca cggccttggg ggtgttagtg gtggcgctgg gagcacgtga gcactggggc    660

acatggggca cgtctcagcg tccggccgtt ttgtgatttt gaagtttgaa ttctctgtgg    720

gcaaaggcag ccatcacagg cctagtgggt ttcaactcca acgcacacca gggtgtcaga    780

gcatgggagg ccccggcctc tggagagcct gtccttggct gggtttcagc ctcggaggca    840

gagtgtgagg cccctgaggg caaaggtctt tggtgccaag gcaggtctgg ctggccgggc    900

tgttggc                                                              907


<210>  7489
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  7489

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Val Arg Val Ser Trp Pro Ala Pro Ala Gly Pro Pro Arg 
            100                 105                 110


Gly Ser Ser Gln Leu Cys Pro Trp Gly Cys Leu Cys Arg Arg Arg Cys 
        115                 120                 125


Ala Gly Ala Gln Gly Ala Pro Val Arg Pro Asp Leu Arg Ala Ser Ala 
    130                 135                 140


Gln Arg Gln Ala Pro His Lys Val Met Leu Arg His Gly Leu Gly Gly 
145                 150                 155                 160


Val Ser Gly Gly Ala Gly Ser Thr 
                165


<210>  7490
<211>  792
<212>  DNA
<213>  Homo sapiens

<400>  7490
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg gcccatggac agaccttcac gttcccagat ctgtttcccg    480

agaaagacga gagccctgaa ggcagcgctg ccgacgacct ctacagcatg ctcgaggagg    540

agaggcagca gaggcagagc agcgacccgc ggcggggcgg cgtccccagc tggttcgggc    600

tgtgacgggg tggccagcag ggacgcgccc caggtgggca gctgtggcag agcagcgacc    660

cgcggcgggg cggcatcccc agctggttcg ggccgtgacg gggcggccag cagggacgcg    720

ccccaggtgg gcagctgtgg cagagcagtc ccgacaccta aataaaagtc ttgctgcagg    780

agaaagagcc gg                                                        792


<210>  7491
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  7491

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Ala His Gly Gln Thr Phe Thr Phe Pro Asp Leu Phe Pro 
            100                 105                 110


Glu Lys Asp Glu Ser Pro Glu Gly Ser Ala Ala Asp Asp Leu Tyr Ser 
        115                 120                 125


Met Leu Glu Glu Glu Arg Gln Gln Arg Gln Ser Ser Asp Pro Arg Arg 
    130                 135                 140


Gly Gly Val Pro Ser Trp Phe Gly Leu 
145                 150


<210>  7492
<211>  701
<212>  DNA
<213>  Homo sapiens

<400>  7492
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg gcccatggac agaccttcac gttcccagat ctgtttcccg    480

agaaagacga gagccctgaa ggcagcgctg ccgacgacct ctacagcatg ctcgaggagg    540

agaggcagca gaggcagagc agcgacccgc ggcggggcgg cgtccccagc tggttcgggc    600

tgtgacgggg tggccagcag ggacgcgccc caggtgggca gctgtggcag agcagtcccg    660

acacctaaat aaaagtcttg ctgcaggaga aagagccgga a                        701


<210>  7493
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  7493

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Ala His Gly Gln Thr Phe Thr Phe Pro Asp Leu Phe Pro 
            100                 105                 110


Glu Lys Asp Glu Ser Pro Glu Gly Ser Ala Ala Asp Asp Leu Tyr Ser 
        115                 120                 125


Met Leu Glu Glu Glu Arg Gln Gln Arg Gln Ser Ser Asp Pro Arg Arg 
    130                 135                 140


Gly Gly Val Pro Ser Trp Phe Gly Leu 
145                 150


<210>  7494
<211>  1036
<212>  DNA
<213>  Homo sapiens

<400>  7494
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg gtgccgcacc ctcggtccct gcctctctgt ctccagcacc    480

gctcacagct ccgcaccccc agaattccct gcattgtcgc ctttgcgtct tggggccctg    540

ggagcaagca cgatgcctgc agtgccctgt gcgtggtggc cagggcctgg gctgcggtgt    600

acgtgagtgc ccgtctcatc tccgtagccg gctaagagtc ctttcaaggc caagaattct    660

tctctttgac cacatttcca cccctccgcc tgccctagga tgctctccat agtggacgct    720

gcactttgcc atggcatgcc gggtggacag gactgctggg gcccccgtgt tccagcctct    780

cctgcgcctc cagatacggc tgcttcctgg gtctgggtgt ctgaggggac gtccctcaag    840

gttcccaccc agctcagcct gtcaggagcc gcaccctgcg aggcctgaga ccacaccatg    900

ccgggtgggg acacacgggc cctgagtgac ctgttgggca tctgcgttca ccaccccacc    960

ctgtctgaga tcatccccag caccagtccc cccaaatcgc ttcattattt ctttgtaaat   1020

agggcttttt ctagtc                                                   1036


<210>  7495
<211>  163
<212>  PRT
<213>  Homo sapiens

<400>  7495

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Val Pro His Pro Arg Ser Leu Pro Leu Cys Leu Gln His 
            100                 105                 110


Arg Ser Gln Leu Arg Thr Pro Arg Ile Pro Cys Ile Val Ala Phe Ala 
        115                 120                 125


Ser Trp Gly Pro Gly Ser Lys His Asp Ala Cys Ser Ala Leu Cys Val 
    130                 135                 140


Val Ala Arg Ala Trp Ala Ala Val Tyr Val Ser Ala Arg Leu Ile Ser 
145                 150                 155                 160


Val Ala Gly 



<210>  7496
<211>  675
<212>  DNA
<213>  Homo sapiens

<400>  7496
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg ccctcccaga cacccagcaa ggagcaaaat ggccagggca    480

gcaccctctg tttccggagc agctgcagca aggggtggtc aacctggggg accagggacc    540

ccagacccgc ttggagtcct gtgggtggcc gcattcccag gaaggctgga tccggaggac    600

cggccaacag gatcgctcag gatggacgtc ttctactcaa gtaagacctt ggcagccttg    660

gtcggctcca tagtc                                                     675


<210>  7497
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  7497

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Pro Ser Gln Thr Pro Ser Lys Glu Gln Asn Gly Gln Gly 
            100                 105                 110


Ser Thr Leu Cys Phe Arg Ser Ser Cys Ser Lys Gly Trp Ser Thr Trp 
        115                 120                 125


Gly Thr Arg Asp Pro Arg Pro Ala Trp Ser Pro Val Gly Gly Arg Ile 
    130                 135                 140


Pro Arg Lys Ala Gly Ser Gly Gly Pro Ala Asn Arg Ile Ala Gln Asp 
145                 150                 155                 160


Gly Arg Leu Leu Leu Lys 
                165


<210>  7498
<211>  725
<212>  DNA
<213>  Homo sapiens

<400>  7498
gggcgcgcgg cacgggcgct ggcgcgtgcg gggggggcgg cgcggcctcc ggaagcgagg     60

gggcgctgtg ccaggcggcg gccgtgcggg gcgggcgcgc tgctccttcc gcctcgcgga    120

ccccggaagc gcgcgtggcc gccatggcgc ggaatgtggt gtaccccctg taccggctgg    180

gtggcccaca acttcgggtg ttccgaacca acttcttcat tcagctggtg cggcccggtg    240

tggcccagcc cgaggacacc gtgcagttcc ggatccccat ggaaatgaca agggtggacc    300

tcaggaatta cctcgagggc atctataacg tgcccgtggc tgctgtgcgg acacgggtgc    360

agcatggctc taacaagaga agagatcaca gaaacgtgag gatcaagaag ccggactaca    420

aggtcgccta cgtgcagctg ccctcccaga cacccagcaa ggagcaaaat ggccagggca    480

gcaccctctg tttccggagc agctgcagca aggggtggtc aacctggggg accagggacc    540

ccagacccgc ttggagtcct gtgggtggcc gcattcccag gaaggctgga tccggaggac    600

cggccaacag gatcgctcag gatggacgtc ttctactcaa gaacctcagg cccagagtcc    660

ccaggaggga gcagccggca acacggtttc cgctgtggag acggggcgtc ctggcttgag    720

ttcac                                                                725


<210>  7499
<211>  191
<212>  PRT
<213>  Homo sapiens

<400>  7499

Met Ala Arg Asn Val Val Tyr Pro Leu Tyr Arg Leu Gly Gly Pro Gln 
1               5                   10                  15


Leu Arg Val Phe Arg Thr Asn Phe Phe Ile Gln Leu Val Arg Pro Gly 
            20                  25                  30


Val Ala Gln Pro Glu Asp Thr Val Gln Phe Arg Ile Pro Met Glu Met 
        35                  40                  45


Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr Asn Val Pro 
    50                  55                  60


Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn Lys Arg Arg 
65                  70                  75                  80


Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys Val Ala Tyr 
                85                  90                  95


Val Gln Leu Pro Ser Gln Thr Pro Ser Lys Glu Gln Asn Gly Gln Gly 
            100                 105                 110


Ser Thr Leu Cys Phe Arg Ser Ser Cys Ser Lys Gly Trp Ser Thr Trp 
        115                 120                 125


Gly Thr Arg Asp Pro Arg Pro Ala Trp Ser Pro Val Gly Gly Arg Ile 
    130                 135                 140


Pro Arg Lys Ala Gly Ser Gly Gly Pro Ala Asn Arg Ile Ala Gln Asp 
145                 150                 155                 160


Gly Arg Leu Leu Leu Lys Asn Leu Arg Pro Arg Val Pro Arg Arg Glu 
                165                 170                 175


Gln Pro Ala Thr Arg Phe Pro Leu Trp Arg Arg Gly Val Leu Ala 
            180                 185                 190


<210>  7500
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  7500
gggtggcgga ggagcccccc gccaggtacc ccctgtaccg gctgggtggc ccacaacttc     60

gggtgttccg aaccaacttc ttcattcagc tggtgcggcc cggtgtggcc cagcccgagg    120

acaccgtgca gttccggatc cccatggaaa tgacaagggt ggacctcagg aattacctcg    180

agggcatcta taacgtgccc gtggctgctg tgcggacacg ggtgcagcat ggctctaaca    240

agagaagaga tcacagaaac gtgaggatca agaagccgga ctacaaggtc gcctacgtgc    300

agctggccca tggacagacc ttcacgttcc cagatctgtt tcccgagaaa gacgagagcc    360

ctgaaggcag cgctgccgac gacctctaca gcatgctcga ggaggagagg cagcagaggc    420

agagcagcga cccgcggcgg ggcggcgtcc ccagctggtt cgggctgtga cggggtggcc    480

agcagggacg cgccccaggt gggcagctgt ggcagagcag cgacccgcgg cggggcggca    540

tccccagctg gttcgggccg tgacggggcg gccagcaggg acgcgcccca ggtgggcagc    600

tgtggcagag cagtcccgac acctaaataa aagtcttgct gcaggagaaa gagccgg       657


<210>  7501
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  7501

Met Glu Met Thr Arg Val Asp Leu Arg Asn Tyr Leu Glu Gly Ile Tyr 
1               5                   10                  15


Asn Val Pro Val Ala Ala Val Arg Thr Arg Val Gln His Gly Ser Asn 
            20                  25                  30


Lys Arg Arg Asp His Arg Asn Val Arg Ile Lys Lys Pro Asp Tyr Lys 
        35                  40                  45


Val Ala Tyr Val Gln Leu Ala His Gly Gln Thr Phe Thr Phe Pro Asp 
    50                  55                  60


Leu Phe Pro Glu Lys Asp Glu Ser Pro Glu Gly Ser Ala Ala Asp Asp 
65                  70                  75                  80


Leu Tyr Ser Met Leu Glu Glu Glu Arg Gln Gln Arg Gln Ser Ser Asp 
                85                  90                  95


Pro Arg Arg Gly Gly Val Pro Ser Trp Phe Gly Leu 
            100                 105


<210>  7502
<211>  4753
<212>  DNA
<213>  Homo sapiens

<400>  7502
gtaccccctg taccggctgg gtggcccaca acttcgggtg ttccgaacca acttcttcat     60

tcagctgggc tgtgagcagg caggactgcc ctcccgaagc aggtgcagaa cgagcatttg    120

gggaaggaga agacacgtgt ccgcacctgc agctggtggg gtgggagggt gagctgcctg    180

cagggtggtg gggggcagcc cgggggggct cctgaggatg cacagctccc tcccaaggcc    240

agggctctgg gcactggggt ccaggagaga gttttgctct gcccatggcc aacaggtagg    300

tgcccagatg ctgttctgtg gtggagtgag gggaccttat tccctggggc ccagaggatg    360

cccagctctg ccaagggcct tgaatgactc catcagagga ggtccggagc cccagggcca    420

ttccctgatt cctgtcactt tcccaggatg ccctccctca ccgggtcggc tcccagctcc    480

ccttggagtg aggagggctg gaccccactg agtccatcgc agaccccagc tggccgggcg    540

catggcttcc cgtctcctct ctgggcttgg tcctcttgtg tgaggggtca cggcccaggc    600

acccatctcc tctgggttga ggctggaggg tgtctccggg aagcccctac gagtgcaaaa    660

ccttgctgtt gatctcaaga ccccgggcgg agacgggagg aggagggtgg aggaacgaag    720

accagattcc tggaggacga ttctgttgag cctccaattc cctggactga ttatttgctt    780

aagtcagaac tcccggccgg atggggctgg ggccaggaga tcagggagag ggttctttcc    840

tggacaggtc tgcttatccc aagggccaat tagcagtagc agagcctcag caggagcttg    900

cttgtcctgg gagcaggggt gagcttatct gctccgaggg gtgccctgcc gggcctcggg    960

gccttggaga ggggccggct ccgttctccg tctcctggaa agccaaggtg ggaggtagca   1020

tctggaatta gatgcggttg aggatgcttc ctgactggga gggggttttg ctcctccctg   1080

ggaccacagc aggacatttg aagcaccagg atcccagcgg gggcctgtgg ggaggcatgg   1140

ccatttctaa atgaggctct gggtacctgg tggcccatgg agcggggctc tgggaattgc   1200

ctcctgcgag cggccattgg agggggaggt attaccccca ccggtgtcct cagccagtcc   1260

ctcctggagt cctcagagcc ctcaacaggc tctcacctgg ccctccgctg ccagggctgg   1320

accagaggct cttcaggagc ttgtgctctt ccgcccccag agctccagcc tggacgcctt   1380

ggaactggcc gtcctgagct ggacagccaa gatgcgatgg tggctgtgct gggctccagc   1440

ccatggtggc ctccaaggtg gtgctggggc cttaggggaa agggttgctt ttcatggctg   1500

gctgagggga tggcagagct gtcctccgtt ccgcctcctt tacccatgga tgcggccgca   1560

tgcgggtctc catcattgtc ctatccttga ccatctggct aagactcagg gacccacagc   1620

agccgctccc ccactggctg tctgggaaaa ggcccacatt gccgggcaca caccagggtg   1680

gccagggatt ggtcactgcc tgaatgtccc cggaccgatg cccgtgtgcc cttgggcagc   1740

cttcccctcg gacaggctgt ccaggctggg aaaccctgag ccagagggat taagaagaaa   1800

ggacagagtc gactgtcccc ttggctaatt tgtgcttcat ttagtgtaat tttgctcagt   1860

ggtcaaaaca tagaggtgat gacaccgagg gtccagacat gtcccatctc cagggccaac   1920

ctcctgcaga tccccagccc cgcccagccc tgcctgctgc gccctgggcc tgcctctgcc   1980

ctcacagcca tcctgtacat tcctgtgtct cagtggcggg ggataggggg tgggggaagg   2040

gtctccgata caccaggggg tgcagggacc ctcagcatgg gtgcccaggc agctctctat   2100

ggaaatgcag gattgggtca ggaccccaga gctgtgcagg gccctctgtc cccagcccaa   2160

gtcctgagtc cctcttgcca gcctctgctg ctccgcgtgt ggtaggagct accagtctgg   2220

ggtccgggct gggcgcattc atgatgcctg cctggggtct gagcaaatcc tccccacggg   2280

gtctgagcaa gtcctcccca cggggtctga gcaaatcctc cccacggggt ctgagcatgt   2340

cctccccacg gggtctgagc aaatcctccc cacggggtct gagcaagtcc tccccatggg   2400

gcctgagcaa atcctcccca cggggtctga gcatgtcctc cccacggggt ctgagcaaat   2460

cctccccacg gggtctgagc aaatcctccc catggggtct gagcaaatcc ttcctatgcc   2520

gtctgagcaa gtcctcccca tgggttctga gcatgtcctc cccacagggt ctgagcaagt   2580

cctccccacg gggtctgagc aagtcctccc cacggggtct gagcatgtcc tccccacggg   2640

gtctgagcaa gtcctcccca cggggtctga tcatgtcctc cccacggggt ctgagcatgt   2700

cctctccacg gggtctgagc aagtcctccc catggggtct gagcatgtcc tccccacggg   2760

gtctgagcaa gtcctcccca cggggtctat gtcctcccca cggggtctga gcatgtcctc   2820

cccatgggtt ctgagcaagt cctccccatg gggtctgagc aagtcctccc cacggggtct   2880

gagcaaatcc tccccatggg gtctgagcaa atccttccta tgccgtctga gcacatcctc   2940

cccaagctgt gaccgagtgt ccctcctgca ggtggaggat gttgctagga tgcaccttga   3000

aggcacccca gcctcgccgg agcgccccct cctcgtagcc tggggtgtgg ctgggtggtc   3060

tggggtcctg ggtgccttgt gatgctggcc ccagggtcca ctcagcaccg tcctggtgtc   3120

gtcatcagct ggaggcttcc cggggcctgt gctgggggtg gagagcaggg agaggcagca   3180

gggttctcct cagggtgggg ttgctgggaa gcaccatccc acctgtcaga ctggccttga   3240

ctgtagacac cccaggtgac ctggaaggac agacggaccc caggtgatga gaaaggacca   3300

gagtctgacc tctcacccct cctaagctct gaactcccgt tggcttgcct gacctccaag   3360

tcctcctggg gctgaaccct ctacagatgc ccctcctggg ccctggggtg ggcccggttt   3420

agctctccat tgtggctgaa acccccaggg cttcagtgct ggcttgaaga gggggtgggg   3480

ctccccaggc gtggggattg gcagtttttt cctcccctct tcccaaactt tcagactgga   3540

ccacttaaga ataatgaggt ccaggtggtt ccgcttgagc ctggatcctc actggctgtg   3600

ggactgagct tcccctgccg gtcccacctc ccaccgggag cagctaatga cagccagagg   3660

ctggaaggtg aagctcccct cggctgtcag gcgggccgca gggcaggggc tgggcaggcc   3720

aagggcgcca ctctcctgcc caggccaggg cacccgatca ctgcaccaca ccccttgtgg   3780

ccgtctgtcc agccagggcc ctgctgcagg tgcttcccgt gggactgtag ggagaacaat   3840

caagacttct gcctccttgg tcgagcaggg ctgcctcccc atctcatcta ctggcaagga   3900

ggctgggcac cttcagggag cttcagtttg ggaagaggga ggaggtctga ggtggatggt   3960

ggcgatggct gcgcagcagt gagaatggac tgagtgccac tgatgtgtgt gctccatggc   4020

tccgtggctc cgtggctccg tggctcagtg gctcaatggc tataatggct agttttgtta   4080

catattttca ccataataaa acaaaacatg tccaaggtgc tacaaggagg gaggagcccc   4140

tggagcaccc gcctgccatc tcccatctgc caggcagcat ccctccactg gctctctggg   4200

aggggttcca ggcctccagc ctccctgtgg cccccatctg cctccaggag atttgttccc   4260

tctctcctgc cccgaaaccc tcgaggcagc cctgctcttg gtcactgcag aggaagtggc   4320

ccaggcttgg cccaggccag ctgtggcctc tggaggcaag atgtggggac tcacagtgtt   4380

cgaaggccac acccccccga gcacatgggc tccagtgcct ctgaggcaaa gagcaggcag   4440

caccgtgcgc acagcagtgg gagacacagc acagccacca gggcagcccc caggcagacg   4500

gcgggcctag agagggcggg atgacacaag aaaggttctc ctttggagac ggcgaggtca   4560

ggcaggtggg agagggttca cggtgcttga ggtgcagaga gaggatggtg gaatggaaaa   4620

cgtagggtga cttgtcgggg acaggcccag ggccacaact cgggcaggcc tattgcccga   4680

gttttgggtc ccatcctggc aggcagggga gagaattctg aattttttaa tgaaacggat   4740

agttgagggc tgg                                                      4753


<210>  7503
<211>  303
<212>  PRT
<213>  Homo sapiens

<400>  7503

Met Ser His Leu Gln Gly Gln Pro Pro Ala Asp Pro Gln Pro Arg Pro 
1               5                   10                  15


Ala Leu Pro Ala Ala Pro Trp Ala Cys Leu Cys Pro His Ser His Pro 
            20                  25                  30


Val His Ser Cys Val Ser Val Ala Gly Asp Arg Gly Trp Gly Lys Gly 
        35                  40                  45


Leu Arg Tyr Thr Arg Gly Cys Arg Asp Pro Gln His Gly Cys Pro Gly 
    50                  55                  60


Ser Ser Leu Trp Lys Cys Arg Ile Gly Ser Gly Pro Gln Ser Cys Ala 
65                  70                  75                  80


Gly Pro Ser Val Pro Ser Pro Ser Pro Glu Ser Leu Leu Pro Ala Ser 
                85                  90                  95


Ala Ala Pro Arg Val Val Gly Ala Thr Ser Leu Gly Ser Gly Leu Gly 
            100                 105                 110


Ala Phe Met Met Pro Ala Trp Gly Leu Ser Lys Ser Ser Pro Arg Gly 
        115                 120                 125


Leu Ser Lys Ser Ser Pro Arg Gly Leu Ser Lys Ser Ser Pro Arg Gly 
    130                 135                 140


Leu Ser Met Ser Ser Pro Arg Gly Leu Ser Lys Ser Ser Pro Arg Gly 
145                 150                 155                 160


Leu Ser Lys Ser Ser Pro Trp Gly Leu Ser Lys Ser Ser Pro Arg Gly 
                165                 170                 175


Leu Ser Met Ser Ser Pro Arg Gly Leu Ser Lys Ser Ser Pro Arg Gly 
            180                 185                 190


Leu Ser Lys Ser Ser Pro Trp Gly Leu Ser Lys Ser Phe Leu Cys Arg 
        195                 200                 205


Leu Ser Lys Ser Ser Pro Trp Val Leu Ser Met Ser Ser Pro Gln Gly 
    210                 215                 220


Leu Ser Lys Ser Ser Pro Arg Gly Leu Ser Lys Ser Ser Pro Arg Gly 
225                 230                 235                 240


Leu Ser Met Ser Ser Pro Arg Gly Leu Ser Lys Ser Ser Pro Arg Gly 
                245                 250                 255


Leu Ile Met Ser Ser Pro Arg Gly Leu Ser Met Ser Ser Pro Arg Gly 
            260                 265                 270


Leu Ser Lys Ser Ser Pro Trp Gly Leu Ser Met Ser Ser Pro Arg Gly 
        275                 280                 285


Leu Ser Lys Ser Ser Pro Arg Gly Leu Cys Pro Pro His Gly Val 
    290                 295                 300


<210>  7504
<211>  493
<212>  DNA
<213>  Homo sapiens

<400>  7504
tagcaagtta agatggcttc ttgtatttgc ttaggtcccc aaggagcagt atcccctcct     60

tctcgtgaac ccgagccaca tgctgtggcc tgggctgggg cttggctgac acggacatat    120

tctgaactct cagcagaaga tgcccatgga cagaccttca cgttcccaga tctgtttccc    180

gagaaagacg agagccctga aggcagcgct gccgacgacc tctacagcat gctcgaggag    240

gagaggcagc agaggcagag cagcgacccg cggcggggcg gcgtccccag ctggttcggg    300

ctgtgacggg gtggccagca gggacgcgcc ccaggtgggc agctgtggca gagcagcgac    360

ccgcggcggg gcggcatccc cagctggttc gggccgtgac ggggcggcca gcagggacgc    420

gccccaggtg ggcagctgtg gcagagcagt cccgacacct aaataaaagt cttgctgcag    480

gagaaagagc cgg                                                       493


<210>  7505
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  7505

Met Pro Met Asp Arg Pro Ser Arg Ser Gln Ile Cys Phe Pro Arg Lys 
1               5                   10                  15


Thr Arg Ala Leu Lys Ala Ala Leu Pro Thr Thr Ser Thr Ala Cys Ser 
            20                  25                  30


Arg Arg Arg Gly Ser Arg Gly Arg Ala Ala Thr Arg Gly Gly Ala Ala 
        35                  40                  45


Ser Pro Ala Gly Ser Gly Cys Asp Gly Val Ala Ser Arg Asp Ala Pro 
    50                  55                  60


Gln Val Gly Ser Cys Gly Arg Ala Ala Thr Arg Gly Gly Ala Ala Ser 
65                  70                  75                  80


Pro Ala Gly Ser Gly Arg Asp Gly Ala Ala Ser Arg Asp Ala Pro Gln 
                85                  90                  95


Val Gly Ser Cys Gly Arg Ala Val Pro Thr Pro Lys 
            100                 105


<210>  7506
<211>  1904
<212>  DNA
<213>  Homo sapiens

<400>  7506
ggtggcagca tggcctgggg gtcctggcac cgctgctcct ctgcccaccc taacttcccg     60

gcatggcggc tgccccctct gagcgtcccc aaccaaactg caggggatat gaagcaagct    120

ggacttgggg agacatctct gctcgagtgc acgttggcct gatgacgact gctcttgggt    180

tcacgggttc caggctctgc ccgggagcct catgcaaact ggtcccgttc tacagacgag    240

gaaactgagg cacagagtga ttacggctgt ccctgagctc ctgcagccag taagtgtctc    300

tgaggatgaa ctgccatgtg cccggcgggg atgccgtccc tggcccttgc tgagtgcctc    360

tgggacgagg tcagctgagc ctgccatcct aactcagaca ccatctcact ctccaagtcc    420

cttctcggcc cagcaaattc tcacctccag aggccaggtc tgccccgcag gtcttaggaa    480

atacagccct acttccatcc agcacaccaa cccaaggaag tgcctcggag ccctggggcc    540

cgaggggggc ctggccttgg tctcacggcg gcagctccac ctggagagga gtgaactcaa    600

gccaggacgc cccgtctcca cagcggaaac cgtgttgccg gctgctccct cctggggact    660

ctgggcctga ggttcctgtg ggagttgggg ggatagctga gtcctatgga ggtgcccctc    720

tcctccccgc ccagtggagc ttggggtggg gacaggcgaa gacagggtga gaagcacggg    780

gcattccccc tccacacagc gctgagaaag taagggagca tccagaaaac ggtgcccact    840

tccgcgtcag gcggatatca cgggcaccag ctccaggtga ccctagccca gccagagaac    900

aaggaccagg ttgtgccgca aagcccgtgt ccgctccctc ccgcctggga ccactgtggc    960

gaggggaagg gagcgtggtg gccctctcct gactcctgag gcctgaagtc caagctcccg   1020

gccctcaggc aggccagggt ctagacaccg ctgccccaaa cacacccccc agtccccgcc   1080

cgcaggcttc ctgcaggatc ccccagtgca cctgggggct gaggagagtg agcagggcgc   1140

aaagaagctt cgtcgggagg gcggtcccca cccgccttgg acccccgggg atagtgtcct   1200

ggggcctggg ctcagatgca ccctgggagg aatggtgcgg aggctgtttt ttgctccaag   1260

aggacattgc ctcagcagag ggctgccgag ctgggaggac ccacagtgca aggccgcaga   1320

accccctagg aagcctcaga gccttcaggt tccgggctga ggctgtgggc gtggaccctt   1380

gtgcaaaccc cactggaaga aaaaccttac agctcaggag gaggaggggc cccacccgct   1440

cccagagccc gtaaacgagg ggtggtgccc acatgaggcc tggggaaggg ctggggctgg   1500

gacaccccct caccaccccc agatacccca ggcagcccct ccctccacag agagacccac   1560

tgggcctgac cctgccctgg gcacagggtc gagccaggga cggcccgtgg gagaaagacg   1620

gcttcatggg ccgctggccg ggccaggtgc gtccttcccc agttctaggt ggcaaatggg   1680

gtggggccag agccttctgg ctagggaaga cactggcctg gttggtgtgg caggggcagc   1740

gaaggagggt caaaggccac tctggcctgg aagagtcccc agccacctgg acgggggtag   1800

ccaggcctgg tccctgcccc cactctccaa ggggtcgggg cagccgggca gagccagtaa   1860

gtgtttgttt tcagatgaca tttgtaaaga aaaacagcct ccca                    1904


<210>  7507
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  7507

Met Gln Thr Gly Pro Val Leu Gln Thr Arg Lys Leu Arg His Arg Val 
1               5                   10                  15


Ile Thr Ala Val Pro Glu Leu Leu Gln Pro Val Ser Val Ser Glu Asp 
            20                  25                  30


Glu Leu Pro Cys Ala Arg Arg Gly Cys Arg Pro Trp Pro Leu Leu Ser 
        35                  40                  45


Ala Ser Gly Thr Arg Ser Ala Glu Pro Ala Ile Leu Thr Gln Thr Pro 
    50                  55                  60


Ser His Ser Pro Ser Pro Phe Ser Ala Gln Gln Ile Leu Thr Ser Arg 
65                  70                  75                  80


Gly Gln Val Cys Pro Ala Gly Leu Arg Lys Tyr Ser Pro Thr Ser Ile 
                85                  90                  95


Gln His Thr Asn Pro Arg Lys Cys Leu Gly Ala Leu Gly Pro Glu Gly 
            100                 105                 110


Gly Leu Ala Leu Val Ser Arg Arg Gln Leu His Leu Glu Arg Ser Glu 
        115                 120                 125


Leu Lys Pro Gly Arg Pro Val Ser Thr Ala Glu Thr Val Leu Pro Ala 
    130                 135                 140


Ala Pro Ser Trp Gly Leu Trp Ala 
145                 150


<210>  7508
<211>  2910
<212>  DNA
<213>  Homo sapiens

<400>  7508
atgggaggca gggcgggggc ggccaagcct ctccagccgc tcccttcccg cttgccccac     60

agacgggcct ccctggatgg tcctgggtca gcacacacgc tcccaggcgc ttccttcccc    120

aggagacagt ccccagcccc tggcggccca gatcctcctg ctcaggccga cgcatcccac    180

ctgggcccca gaaacctctt tggaaaggga cagtcacctc agagtggcaa gcacttaaaa    240

gagaccccca acaggccggt gtgtcgtggt ggcaggcagg gtgtgtctgg agagaagggg    300

gacgtgtccc cagctgggcc tgggggcggc tccgtgggaa agtcccacct ggtcccagcc    360

ccgggtctcc agccttcaga ctccttgggg gtctctgtgg cctggcagag gtcggtggcc    420

cctcagtgga ggtgaggcct ctcctgggtc accaccgcac accggcctgc tgggaagctg    480

gggttctggg ccacagccgg ccctggacgt ggaggggggc atcaggccag accccccagg    540

ggctcacagg gctctgggag gccctggcaa ccccagggtg cccccaagcc ctcagaaggg    600

ttgtccctac ttggagggga ccacacagcc aggtgggcag gaacaggcac cacggcggcc    660

cttccctgtc caccctctca ccagtggccc gcagtgcagt ccaggaagca ccggacagag    720

cacggggcag ggaggggagg cccgtactgg cttcacagag gtctgggagg ggctagcccc    780

tgtgcagaca gacccctgaa gcctagagcc gccggcccag ctgaggtcct tcccaggggc    840

cattctggga cccctgaccc catgcacctg tgtcacaggg ctatgagcgc ccccagcccc    900

aggacctcca cgtttctctc tagagggaag aggaggagga cggcaggcct gctggcccca    960

cacttactgg ttggggacgc tcagaggggg cagccgccat gccgggaagt tagggtgggc   1020

agaggagcag cggtgccagg acccccaggc catgctgcca ccccggaccc tgaacaccct   1080

gccctgggtc catatgctca gagctggcta catatcctgt ggctgcccat gacacatagc   1140

tcccccaggc agggccggac cccgggcacc tctttgcctc cagggccggc cccactctgt   1200

tggaggtcag ccggttccga ggcctccaag ccgcctttct acttctcgat tccagggcct   1260

ggtctccact ccctctgggc tttggggtgc atgctgcagt gcagcctccc cgcgccccgg   1320

cctccatgca ccctgctcgt gctgcctcag aggcttggca tctcccccat cttccagcca   1380

ggcagccagt tttctgcaac gtggggccca cggtcagcgt cccccacagc cctgccagcc   1440

cttctccccg ggggtccgcc ctgcaccccc ttcccaggag cttgctctgc acccactgct   1500

gggcctcctg gcctaggggc ttggcacgtg cctgtgagca gaggcgctgg gcaggaggag   1560

gaggaggagc ctgcagtgcc tggcgcccgt gtgtgtttac tggtccggcc ccagccccgc   1620

gccgctcccc gcggacccgg cctcccgcct gtgtccagcc aggtgttggg tgatggagcg   1680

gggctcccta aggacaagga gcacagtgtc tgctttcttt gcaagcacag tgctgacaag   1740

gaacagaata cccacagcga ctgcttccag gaaacggctg cagggcgggc gggagcctct   1800

gcgagagcag ccccttccca gcaagccggc ctgcaggtgg gcttccagga aggggccccc   1860

gctggcttcc ctcagccctg gaagggggcc aacggtgtca ccaggagcag gccagggagc   1920

gggggaacac caccccgcta cagggccacg atcacacaca caccccgcgg agcatctccg   1980

ggccggacag gacccacgcc ctccacagcc cggaaaggcg ggttaactgg tcagcatgca   2040

gagacccacc aagtggagac cccgctccca ggcacagacg cacagctgtg gatgcacgtc   2100

ctcggaaatc gggttgggcc aaagataaac acacattcca acctggcagg tcgctcagag   2160

ctaggggctc gggcgggctc ccagcccccg ccccggggtg cggcaggagg ctccgaggct   2220

gagcacctgc tgcggggccc ccgggcctgt ggctccccgc ctgcccgcct caccctgagg   2280

ttcagccccc tgaacgctgc ccccaccacc tccctgtttc agggcctgtg gcccagaccc   2340

cctccagcac tcaggggctg ccctagggac accaccccag gaactgccct aggaagcccg   2400

ttccgctgca gggagcagag aaacctgggc tgcccagagg taggcgctgc ccctgagtac   2460

acgtcctgct ctcagggggc agccagcgtg ggcacagcca tgggcagtgc tgggagatgg   2520

tgggggccac caagaggcct gtgtcccttc cccagcgggt gtgaggagga acagccctgt   2580

ccccatacag ctcccaggtg gaaactccag agcaagcgtg tcattcatac accccgggcc   2640

cagagatgtg gacgtgtcca gcacgcctgt tctctccaag acctctgccc caaggccacc   2700

tgcccactga gaagcccacc ggctccccca caaccccctg gctccttgtg cggggccgtc   2760

cctccggcgt ggccccggct cccacccaca gcaaaagggg agcaggaacg ggactggcgc   2820

ggggttcgtg cccctgtcgg ggtggggtcg cccagagcac cttgtgggcc tcccagagcg   2880

gccatggcca gctctacccc agtcacctag                                    2910


<210>  7509
<211>  682
<212>  PRT
<213>  Homo sapiens

<400>  7509

Met His Leu Cys His Arg Ala Met Ser Ala Pro Ser Pro Arg Thr Ser 
1               5                   10                  15


Thr Phe Leu Ser Arg Gly Lys Arg Arg Arg Thr Ala Gly Leu Leu Ala 
            20                  25                  30


Pro His Leu Leu Val Gly Asp Ala Gln Arg Gly Gln Pro Pro Cys Arg 
        35                  40                  45


Glu Val Arg Val Gly Arg Gly Ala Ala Val Pro Gly Pro Pro Gly His 
    50                  55                  60


Ala Ala Thr Pro Asp Pro Glu His Pro Ala Leu Gly Pro Tyr Ala Gln 
65                  70                  75                  80


Ser Trp Leu His Ile Leu Trp Leu Pro Met Thr His Ser Ser Pro Arg 
                85                  90                  95


Gln Gly Arg Thr Pro Gly Thr Ser Leu Pro Pro Gly Pro Ala Pro Leu 
            100                 105                 110


Cys Trp Arg Ser Ala Gly Ser Glu Ala Ser Lys Pro Pro Phe Tyr Phe 
        115                 120                 125


Ser Ile Pro Gly Pro Gly Leu His Ser Leu Trp Ala Leu Gly Cys Met 
    130                 135                 140


Leu Gln Cys Ser Leu Pro Ala Pro Arg Pro Pro Cys Thr Leu Leu Val 
145                 150                 155                 160


Leu Pro Gln Arg Leu Gly Ile Ser Pro Ile Phe Gln Pro Gly Ser Gln 
                165                 170                 175


Phe Ser Ala Thr Trp Gly Pro Arg Ser Ala Ser Pro Thr Ala Leu Pro 
            180                 185                 190


Ala Leu Leu Pro Gly Gly Pro Pro Cys Thr Pro Phe Pro Gly Ala Cys 
        195                 200                 205


Ser Ala Pro Thr Ala Gly Pro Pro Gly Leu Gly Ala Trp His Val Pro 
    210                 215                 220


Val Ser Arg Gly Ala Gly Gln Glu Glu Glu Glu Glu Pro Ala Val Pro 
225                 230                 235                 240


Gly Ala Arg Val Cys Leu Leu Val Arg Pro Gln Pro Arg Ala Ala Pro 
                245                 250                 255


Arg Gly Pro Gly Leu Pro Pro Val Ser Ser Gln Val Leu Gly Asp Gly 
            260                 265                 270


Ala Gly Leu Pro Lys Asp Lys Glu His Ser Val Cys Phe Leu Cys Lys 
        275                 280                 285


His Ser Ala Asp Lys Glu Gln Asn Thr His Ser Asp Cys Phe Gln Glu 
    290                 295                 300


Thr Ala Ala Gly Arg Ala Gly Ala Ser Ala Arg Ala Ala Pro Ser Gln 
305                 310                 315                 320


Gln Ala Gly Leu Gln Val Gly Phe Gln Glu Gly Ala Pro Ala Gly Phe 
                325                 330                 335


Pro Gln Pro Trp Lys Gly Ala Asn Gly Val Thr Arg Ser Arg Pro Gly 
            340                 345                 350


Ser Gly Gly Thr Pro Pro Arg Tyr Arg Ala Thr Ile Thr His Thr Pro 
        355                 360                 365


Arg Gly Ala Ser Pro Gly Arg Thr Gly Pro Thr Pro Ser Thr Ala Arg 
    370                 375                 380


Lys Gly Gly Leu Thr Gly Gln His Ala Glu Thr His Gln Val Glu Thr 
385                 390                 395                 400


Pro Leu Pro Gly Thr Asp Ala Gln Leu Trp Met His Val Leu Gly Asn 
                405                 410                 415


Arg Val Gly Pro Lys Ile Asn Thr His Ser Asn Leu Ala Gly Arg Ser 
            420                 425                 430


Glu Leu Gly Ala Arg Ala Gly Ser Gln Pro Pro Pro Arg Gly Ala Ala 
        435                 440                 445


Gly Gly Ser Glu Ala Glu His Leu Leu Arg Gly Pro Arg Ala Cys Gly 
    450                 455                 460


Ser Pro Pro Ala Arg Leu Thr Leu Arg Phe Ser Pro Leu Asn Ala Ala 
465                 470                 475                 480


Pro Thr Thr Ser Leu Phe Gln Gly Leu Trp Pro Arg Pro Pro Pro Ala 
                485                 490                 495


Leu Arg Gly Cys Pro Arg Asp Thr Thr Pro Gly Thr Ala Leu Gly Ser 
            500                 505                 510


Pro Phe Arg Cys Arg Glu Gln Arg Asn Leu Gly Cys Pro Glu Val Gly 
        515                 520                 525


Ala Ala Pro Glu Tyr Thr Ser Cys Ser Gln Gly Ala Ala Ser Val Gly 
    530                 535                 540


Thr Ala Met Gly Ser Ala Gly Arg Trp Trp Gly Pro Pro Arg Gly Leu 
545                 550                 555                 560


Cys Pro Phe Pro Ser Gly Cys Glu Glu Glu Gln Pro Cys Pro His Thr 
                565                 570                 575


Ala Pro Arg Trp Lys Leu Gln Ser Lys Arg Val Ile His Thr Pro Arg 
            580                 585                 590


Ala Gln Arg Cys Gly Arg Val Gln His Ala Cys Ser Leu Gln Asp Leu 
        595                 600                 605


Cys Pro Lys Ala Thr Cys Pro Leu Arg Ser Pro Pro Ala Pro Pro Gln 
    610                 615                 620


Pro Pro Gly Ser Leu Cys Gly Ala Val Pro Pro Ala Trp Pro Arg Leu 
625                 630                 635                 640


Pro Pro Thr Ala Lys Gly Glu Gln Glu Arg Asp Trp Arg Gly Val Arg 
                645                 650                 655


Ala Pro Val Gly Val Gly Ser Pro Arg Ala Pro Cys Gly Pro Pro Arg 
            660                 665                 670


Ala Ala Met Ala Ser Ser Thr Pro Val Thr 
        675                 680


<210>  7510
<211>  1023
<212>  DNA
<213>  Homo sapiens

<400>  7510
agtgcctggc gcccgtgtgt gtttactggt ccggccccag ccccgcgccg ctccccgcgg     60

acccggcctc ccgcctgtgt ccagccaggt gttgggtgat ggagcggggc tccctaagga    120

caaggagcac agtgtctgct ttctttgcaa gcacagtgct gacaaggaac agaataccca    180

cagcgactgc ttccaggaaa cggctgcagg gcgggcggga gcctctgcga gagcagcccc    240

ttcccagcaa gccggcctgc agagttggga ttttctgtct ccattcggtg gtataccaag    300

tgcctgcctc ccacacccag ctgcccctaa tccctgcctg aaaacgtgct cctgggtcac    360

ggaattcatg ctgagacaca gccacacaca gccaggctca ggggtccacc ctccagggaa    420

caccaccccg ctacagggcc acgatcacac acacaccccg cggagcatct ccgggccgga    480

caggacccac gccctccaca gcccggaaag gcgggttaac tggtcagcat gcagagaccc    540

accaagtgga gaccccgctc ccaggcacag acgcacagct gtggatgcac gtcctcggtg    600

acaagctccc aggtggaaac tccagagcaa gcgtgtcatt catacacccc gggcccagag    660

atgtggacgt gtccagcacg cctgttctct ccaagtgacc aggaggagac aatccctagg    720

agctgacaca ggtgacgaag gcccgaggtg gcccgccttt tcccccggcc ccattcccat    780

gtgtccttcc ccaggcaggg atttgaagtg ggcagagtct tccatgttct ccaggagagg    840

ttttctgggt gcccctctcc ccctccctac ggttcccctg ccccgccacc ctgggcaccc    900

ctggggctgc ctgccgcacc ctgcagccgc cacctgggga agccggcttt tatctcctga    960

gccctgcttt gtaaacctcc tgcagagttg gatgtttata ataaaggccg tttatagacc   1020

taa                                                                 1023


<210>  7511
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  7511

Met Glu Arg Gly Ser Leu Arg Thr Arg Ser Thr Val Ser Ala Phe Phe 
1               5                   10                  15


Ala Ser Thr Val Leu Thr Arg Asn Arg Ile Pro Thr Ala Thr Ala Ser 
            20                  25                  30


Arg Lys Arg Leu Gln Gly Gly Arg Glu Pro Leu Arg Glu Gln Pro Leu 
        35                  40                  45


Pro Ser Lys Pro Ala Cys Arg Val Gly Ile Phe Cys Leu His Ser Val 
    50                  55                  60


Val Tyr Gln Val Pro Ala Ser His Thr Gln Leu Pro Leu Ile Pro Ala 
65                  70                  75                  80


<210>  7512
<211>  634
<212>  DNA
<213>  Homo sapiens

<400>  7512
agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc cctctgggct     60

cccagaaccc accccgcacc ggcgactcca tcttcatggc caccccctgc ggcggacggt    120

tgaccaccag ccaccacatc atcccagagc tgagctcctc cagcgggatg acgccgtccc    180

caccacctcc ctcttcttct ttttcatcct tctgtctctt tgtttctgag ctttcctgtc    240

tttccttttt tctgagagat tcaaagcctc cacgactctg tttcccccgt cccttctgaa    300

tttaatttgc actaagtcat ttgcactggt tggagttgtg gagacggcct tgagtctcag    360

tacgagtgtg cgtgagtgtg agccaccttg gcaagtgcct gtgcagggcc cggccgccct    420

ccatctgggc cgggtgactg ggcgccggct gtgtgcccga ggcctcaccc tgccctcgcc    480

tagtctggaa gctccgaccg acatcacgga gcagccttca agcattccat tacgccccat    540

ctcgctctgt gcccctcccc accagggctt cagcaggagc cctggactca tcatcaataa    600

acactgttac agcaatttgt ctcgaggact ctgg                                634


<210>  7513
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7513

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7514
<211>  750
<212>  DNA
<213>  Homo sapiens

<400>  7514
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa aggtgaagct    120

agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc agcgcccgca    180

gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg gacggttgac    240

caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc cgtccccacc    300

acctccctct tcttcttttt catccttctg tctctttgtt tctgagcttt cctgtctttc    360

cttttttctg agagattcaa agcctccacg actctgtttc ccccgtccct tctgaattta    420

atttgcacta agtcatttgc actggttgga gttgtggaga cggccttgag tctcagtacg    480

agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc agggcccggc cgccctccat    540

ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc ctcgcctagt    600

ctggaagctc cgaccgacat cacggagcag ccttcaagca ttccattacg ccccatctcg    660

ctctgtgccc ctccccacca gggcttcagc aggagccctg gactcatcat caataaacac    720

tgttacagca atttgtctcg aggactctgg                                     750


<210>  7515
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7515

Met Ala Ala Leu Trp Ala Pro Arg Thr His Asn Met Lys Gly Glu Ala 
1               5                   10                  15


Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr Ile Gly Thr 
            20                  25                  30


Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His Leu His Gly 
        35                  40                  45


His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His His Pro Arg 
    50                  55                  60


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
65                  70                  75                  80


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
                85                  90


<210>  7516
<211>  873
<212>  DNA
<213>  Homo sapiens

<400>  7516
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa agaaatggtg    120

ctacccagct caagcctggg cctttgaatc cggacacaaa accctctagc ttggaaatga    180

atatgctgca ctttacaacc actgcactac ctgactcagg aatcggctct ggaaggtgaa    240

gctagaggaa ccagacctca tcagcccaac atcaaagaca ccatcggaac agcagcgccc    300

gcagcaccca ccccgcaccg gcgactccat cttcatggcc accccctgcg gcggacggtt    360

gaccaccagc caccacatca tcccagagct gagctcctcc agcgggatga cgccgtcccc    420

accacctccc tcttcttctt tttcatcctt ctgtctcttt gtttctgagc tttcctgtct    480

ttcctttttt ctgagagatt caaagcctcc acgactctgt ttcccccgtc ccttctgaat    540

ttaatttgca ctaagtcatt tgcactggtt ggagttgtgg agacggcctt gagtctcagt    600

acgagtgtgc gtgagtgtga gccaccttgg caagtgcctg tgcagggccc ggccgccctc    660

catctgggcc gggtgactgg gcgccggctg tgtgcccgag gcctcaccct gccctcgcct    720

agtctggaag ctccgaccga catcacggag cagccttcaa gcattccatt acgccccatc    780

tcgctctgtg cccctcccca ccagggcttc agcaggagcc ctggactcat catcaataaa    840

cactgttaca gcaatttgtc tcgaggactc tgg                                 873


<210>  7517
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7517

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7518
<211>  953
<212>  DNA
<213>  Homo sapiens

<400>  7518
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa aggtgagggg    120

cttcctgcca cacttggggt ggggggcacg cgagaggagc tgagtgggac ctcactcctt    180

ccccatccac agaaatggtg ctacccagct caagcctggg cctttgaatc cggacacaaa    240

accctctagc ttggaaatga atatgctgca ctttacaacc actgcactac ctgactcagg    300

aatcggctct ggaaggtgaa gctagaggaa ccagacctca tcagcccaac atcaaagaca    360

ccatcggaac agcagcgccc gcagcaccca ccccgcaccg gcgactccat cttcatggcc    420

accccctgcg gcggacggtt gaccaccagc caccacatca tcccagagct gagctcctcc    480

agcgggatga cgccgtcccc accacctccc tcttcttctt tttcatcctt ctgtctcttt    540

gtttctgagc tttcctgtct ttcctttttt ctgagagatt caaagcctcc acgactctgt    600

ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt tgcactggtt ggagttgtgg    660

agacggcctt gagtctcagt acgagtgtgc gtgagtgtga gccaccttgg caagtgcctg    720

tgcagggccc ggccgccctc catctgggcc gggtgactgg gcgccggctg tgtgcccgag    780

gcctcaccct gccctcgcct agtctggaag ctccgaccga catcacggag cagccttcaa    840

gcattccatt acgccccatc tcgctctgtg cccctcccca ccagggcttc agcaggagcc    900

ctggactcat catcaataaa cactgttaca gcaatttgtc tcgaggactc tgg           953


<210>  7519
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7519

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7520
<211>  885
<212>  DNA
<213>  Homo sapiens

<400>  7520
caggtctcca gctggggtgg acgtgcccac cagctgccga aggccaagac gccaggtccg     60

gtggacgtga caagcaggac atgacatggt ccggtgtgac ggcgaggaca gaggaggcgc    120

gtccggcctt cctgaacacc ttaggctggt ggggctgcgg caagaagcgg gtctgtttct    180

ttacttcctc cacggagtcg gcacactatg gctgccctct gggctcccag aacccacaac    240

atgaaaggtg aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga    300

acagcagcgc ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg    360

cggcggacgg ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat    420

gacgccgtcc ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga    480

gctttcctgt ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg    540

tcccttctga atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc    600

ttgagtctca gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc    660

ccggccgccc tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc    720

ctgccctcgc ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca    780

ttacgcccca tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc    840

atcatcaata aacactgtta cagcaatttg tctcgaggac tctgg                    885


<210>  7521
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7521

Met Ala Ala Leu Trp Ala Pro Arg Thr His Asn Met Lys Gly Glu Ala 
1               5                   10                  15


Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr Ile Gly Thr 
            20                  25                  30


Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His Leu His Gly 
        35                  40                  45


His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His His Pro Arg 
    50                  55                  60


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
65                  70                  75                  80


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
                85                  90


<210>  7522
<211>  1169
<212>  DNA
<213>  Homo sapiens

<400>  7522
caggtctcca gctggggtgg acgtgcccac cagctgccga aggccaagac gccaggtccg     60

gtggacgtga caagcaggac atgacatggt ccggtgtgac ggcgaggaca gaggaggcgc    120

gtccggcctt cctgaacacc ttaggctggt ggggctgcgg caagaagcgg gtctgtttct    180

ttacttcctc cacggagtcg gcacactatg gctgccctct gggctcccag aacccacaac    240

atgaaaggtg aggggcttcc tgccacactt ggggtggggg gcacgcgaga ggagctgagt    300

gggacctcac tccttcccca tccacagaaa tggtgctacc cagctcaagc ctgggccttt    360

gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta caaccactgc    420

actacctgac tcaggaatcg gctctggaag gtgagcacca gcgctccttc cggaagcctc    480

caggcccccg agcaccctgc ccccatccca cccacgtgtc gctatctcta ggtgaagcta    540

gaggaaccag acctcatcag cccaacatca aagacaccat cggaacagca gcgcccgcag    600

cacccacccc gcaccggcga ctccatcttc atggccaccc cctgcggcgg acggttgacc    660

accagccacc acatcatccc agagctgagc tcctccagcg ggatgacgcc gtccccacca    720

cctccctctt cttctttttc atccttctgt ctctttgttt ctgagctttc ctgtctttcc    780

ttttttctga gagattcaaa gcctccacga ctctgtttcc cccgtccctt ctgaatttaa    840

tttgcactaa gtcatttgca ctggttggag ttgtggagac ggccttgagt ctcagtacga    900

gtgtgcgtga gtgtgagcca ccttggcaag tgcctgtgca gggcccggcc gccctccatc    960

tgggccgggt gactgggcgc cggctgtgtg cccgaggcct caccctgccc tcgcctagtc   1020

tggaagctcc gaccgacatc acggagcagc cttcaagcat tccattacgc cccatctcgc   1080

tctgtgcccc tccccaccag ggcttcagca ggagccctgg actcatcatc aataaacact   1140

gttacagcaa tttgtctcga ggactctgg                                     1169


<210>  7523
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  7523

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg 
    50                  55


<210>  7524
<211>  1055
<212>  DNA
<213>  Homo sapiens

<400>  7524
acaaccaaca cgttctcccc acacgactct ctcgttctcc ccacagccag gtctccagct     60

ggggtggacg tgcccaccag ctgccgaagg ccaagacgcc aggtccggtg gacgtgacaa    120

gcaggacatg acatggtccg gtgtgacggc gaggacagag gaggcgcgtc cggccttcct    180

gaacacctta ggctggtggg gctgcggcaa gaagcgggtc tgtttcttta cttcctccac    240

ggagtcggca cactatggct gccctctggg ctcccagaac ccacaacatg aaagaaatgg    300

tgctacccag ctcaagcctg ggcctttgaa tccggacaca aaaccctcta gcttggaaat    360

gaatatgctg cactttacaa ccactgcact acctgactca ggaatcggct ctggaaggtg    420

aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga acagcagcgc    480

ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg cggcggacgg    540

ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat gacgccgtcc    600

ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga gctttcctgt    660

ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg tcccttctga    720

atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc ttgagtctca    780

gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc    840

tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc    900

ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca ttacgcccca    960

tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc atcatcaata   1020

aacactgtta cagcaatttg tctcgaggac tctgg                              1055


<210>  7525
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7525

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7526
<211>  1697
<212>  DNA
<213>  Homo sapiens

<400>  7526
gagtaggcgc ccaggcatcg tgcagacagg gcgacatcag ctggggacga tgggcctgag     60

ctagggctgg aaagaagggg gagccaggca ttcatcccgg tcacttttgg ttacaggacg    120

tggcagctgg ttggacgagg ggagctggtg ggcagggttt gatcccaggg cctgggcaac    180

ggaggtgtag ctggcagcag cgggcaggtg aggaccccat ctgccgggca ggtgagtccc    240

ttccctcccc aggcctcgct tccccagcct tctgaaagaa ggaggtttag gggatcgagg    300

gctggcgggg agaagcagac accctcccag cagaggggca ggatgggggc aggagagtta    360

gcaaaggtga catcttctcg gggggagccg agactgcgca aggctggggg gttatgggcc    420

cgttccaggc agaaagagca agagggcagg gagggagcac aggggtggcc agcgtagggt    480

ccagcacgtg gggtggtacc ccaggcctgg gtcagacagg gacatggcag gggacacagg    540

acagaggggt ccccagctgc cacctcaccc accgcaattc atttagtagc aggcacaggg    600

gcagctccgg cacggctttc tcaggcctat gccggagcct cgagggctgg agagcgggaa    660

gacaggcagt gctcggggag ttgcagcagg acgtcaccag gagggcgaag cggccacggg    720

aggggggccc cgggacattg cgcagcaagg aggctgcagg ggctcggcct gcgggcgccg    780

gtcccacgag gcactgcggc ccagggtctg gtgcggagag ggcccacagt ggacttggtg    840

acgctgtatg ccctcaccgc tcagcccctg gggctggctt ggcagacagt acagcatcca    900

ggggagtcaa gggcatgggg cgagaccaga ctaggcgagg cgggcggggc ggagtgaatg    960

agctctcagg agggaggatg gtgcaggcag gggtgaggag cgcagcgggc ggcgagcggg   1020

aggcactggc ctccagagcc cgtggccaag gcgggcctcg cgggcggcga cggagccggg   1080

atcggtgccc caacatcaaa gacaccatcg gaacagcagc gcccgcagca cccaccccgc   1140

accggcgact ccatcttcat ggccaccccc tgcggcggac ggttgaccac cagccaccac   1200

atcatcccag agctgagctc ctccagcggg atgacgccgt ccccaccacc tccctcttct   1260

tctttttcat ccttctgtct ctttgtttct gagctttcct gtctttcctt ttttctgaga   1320

gattcaaagc ctccacgact ctgtttcccc cgtcccttct gaatttaatt tgcactaagt   1380

catttgcact ggttggagtt gtggagacgg ccttgagtct cagtacgagt gtgcgtgagt   1440

gtgagccacc ttggcaagtg cctgtgcagg gcccggccgc cctccatctg ggccgggtga   1500

ctgggcgccg gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg gaagctccga   1560

ccgacatcac ggagcagcct tcaagcattc cattacgccc catctcgctc tgtgcccctc   1620

cccaccaggg cttcagcagg agccctggac tcatcatcaa taaacactgt tacagcaatt   1680

tgtctcgagg actctgg                                                  1697


<210>  7527
<211>  292
<212>  PRT
<213>  Homo sapiens

<400>  7527

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Pro Asn Ile Lys Asp Thr Ile Gly Thr Ala Ala Pro Ala Ala Pro 
225                 230                 235                 240


Thr Pro His Arg Arg Leu His Leu His Gly His Pro Leu Arg Arg Thr 
                245                 250                 255


Val Asp His Gln Pro Pro His His Pro Arg Ala Glu Leu Leu Gln Arg 
            260                 265                 270


Asp Asp Ala Val Pro Thr Thr Ser Leu Phe Phe Phe Phe Ile Leu Leu 
        275                 280                 285


Ser Leu Cys Phe 
    290


<210>  7528
<211>  2136
<212>  DNA
<213>  Homo sapiens

<400>  7528
gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg gacatctgga     60

gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg tggggcctga    120

ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg acatcagctg    180

gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc atcccggtca    240

cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc agggtttgat    300

cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg accccatctg    360

ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct gaaagaagga    420

ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag aggggcagga    480

tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga ctgcgcaagg    540

ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag ggagcacagg    600

ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc agacagggac    660

atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc gcaattcatt    720

tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc ggagcctcga    780

gggctggaga gcgggaagac aggcagtgct cggggagttg cagcaggacg tcaccaggag    840

ggcgaagcgg ccacgggagg ggggccccgg gacattgcgc agcaaggagg ctgcaggggc    900

tcggcctgcg ggcgccggtc ccacgaggca ctgcggccca gggtctggtg cggagagggc    960

ccacagtgga cttggtgacg ctgtatgccc tcaccgctca gcccctgggg ctggcttggc   1020

agacagtaca gcatccaggg gagtcaaggg catggggcga gaccagacta ggcgaggcgg   1080

gcggggcgga gtgaatgagc tctcaggagg gaggatggtg caggcagggg tgaggagcgc   1140

agcgggcggc gagcgggagg cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg   1200

gcggcgacgg agccgggatc ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc   1260

agctggggtg gacgtgccca ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg   1320

acaagcagga catgacatgg tccggtgtga cggcgaggac agaggaggcg cgtccggcct   1380

tcctgaacac cttaggctgg tggggctgcg gcaagaagcg ggtctgtttc tttacttcct   1440

ccacggagtc ggcacactat ggctgccctc tgggctccca gaacccacaa catgaaaggt   1500

gaagctagag gaaccagacc tcatcagccc aacatcaaag acaccatcgg aacagcagcg   1560

cccgcagcac ccaccccgca ccggcgactc catcttcatg gccaccccct gcggcggacg   1620

gttgaccacc agccaccaca tcatcccaga gctgagctcc tccagcggga tgacgccgtc   1680

cccaccacct ccctcttctt ctttttcatc cttctgtctc tttgtttctg agctttcctg   1740

tctttccttt tttctgagag attcaaagcc tccacgactc tgtttccccc gtcccttctg   1800

aatttaattt gcactaagtc atttgcactg gttggagttg tggagacggc cttgagtctc   1860

agtacgagtg tgcgtgagtg tgagccacct tggcaagtgc ctgtgcaggg cccggccgcc   1920

ctccatctgg gccgggtgac tgggcgccgg ctgtgtgccc gaggcctcac cctgccctcg   1980

cctagtctgg aagctccgac cgacatcacg gagcagcctt caagcattcc attacgcccc   2040

atctcgctct gtgcccctcc ccaccagggc ttcagcagga gccctggact catcatcaat   2100

aaacactgtt acagcaattt gtctcgagga ctctgg                             2136


<210>  7529
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7529

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7530
<211>  2340
<212>  DNA
<213>  Homo sapiens

<400>  7530
gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg gacatctgga     60

gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg tggggcctga    120

ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg acatcagctg    180

gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc atcccggtca    240

cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc agggtttgat    300

cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg accccatctg    360

ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct gaaagaagga    420

ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag aggggcagga    480

tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga ctgcgcaagg    540

ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag ggagcacagg    600

ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc agacagggac    660

atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc gcaattcatt    720

tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc ggagcctcga    780

gggctggaga gcgggaagac aggcagtgct cggggagttg cagcaggacg tcaccaggag    840

ggcgaagcgg ccacgggagg ggggccccgg gacattgcgc agcaaggagg ctgcaggggc    900

tcggcctgcg ggcgccggtc ccacgaggca ctgcggccca gggtctggtg cggagagggc    960

ccacagtgga cttggtgacg ctgtatgccc tcaccgctca gcccctgggg ctggcttggc   1020

agacagtaca gcatccaggg gagtcaaggg catggggcga gaccagacta ggcgaggcgg   1080

gcggggcgga gtgaatgagc tctcaggagg gaggatggtg caggcagggg tgaggagcgc   1140

agcgggcggc gagcgggagg cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg   1200

gcggcgacgg agccgggatc ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc   1260

agctggggtg gacgtgccca ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg   1320

acaagcagga catgacatgg tccggtgtga cggcgaggac agaggaggcg cgtccggcct   1380

tcctgaacac cttaggctgg tggggctgcg gcaagaagcg ggtctgtttc tttacttcct   1440

ccacggagtc ggcacactat ggctgccctc tgggctccca gaacccacaa catgaaagaa   1500

atggtgctac ccagctcaag cctgggcctt tgaatccgga cacaaaaccc tctagcttgg   1560

aaatgaatat gctgcacttt acaaccactg cactacctga ctcaggaatc ggctctggaa   1620

ggtgagcacc agcgctcctt ccggaagcct ccaggccccc gagcaccctg cccccatccc   1680

acccacgtgt cgctatctct aggtgaagct agaggaacca gacctcatca gcccaacatc   1740

aaagacacca tcggaacagc agcgcccgca gcacccaccc cgcaccggcg actccatctt   1800

catggccacc ccctgcggcg gacggttgac caccagccac cacatcatcc cagagctgag   1860

ctcctccagc gggatgacgc cgtccccacc acctccctct tcttcttttt catccttctg   1920

tctctttgtt tctgagcttt cctgtctttc cttttttctg agagattcaa agcctccacg   1980

actctgtttc ccccgtccct tctgaattta atttgcacta agtcatttgc actggttgga   2040

gttgtggaga cggccttgag tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa   2100

gtgcctgtgc agggcccggc cgccctccat ctgggccggg tgactgggcg ccggctgtgt   2160

gcccgaggcc tcaccctgcc ctcgcctagt ctggaagctc cgaccgacat cacggagcag   2220

ccttcaagca ttccattacg ccccatctcg ctctgtgccc ctccccacca gggcttcagc   2280

aggagccctg gactcatcat caataaacac tgttacagca atttgtctcg aggactctgg   2340


<210>  7531
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7531

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7532
<211>  654
<212>  DNA
<213>  Homo sapiens

<400>  7532
gaaactgggg aagtggggaa ccgaggggca accagacctc atcagcccaa catcaaagac     60

accatcggaa cagcagcgcc cgcagcaccc accccgcacc ggcgactcca tcttcatggc    120

caccccctgc ggcggacggt tgaccaccag ccaccacatc atcccagagc tgagctcctc    180

cagcgggatg acgccgtccc caccacctcc ctcttcttct ttttcatcct tctgtctctt    240

tgtttctgag ctttcctgtc tttccttttt tctgagagat tcaaagcctc cacgactctg    300

tttcccccgt cccttctgaa tttaatttgc actaagtcat ttgcactggt tggagttgtg    360

gagacggcct tgagtctcag tacgagtgtg cgtgagtgtg agccaccttg gcaagtgcct    420

gtgcagggcc cggccgccct ccatctgggc cgggtgactg ggcgccggct gtgtgcccga    480

ggcctcaccc tgccctcgcc tagtctggaa gctccgaccg acatcacgga gcagccttca    540

agcattccat tacgccccat ctcgctctgt gcccctcccc accagggctt cagcaggagc    600

cctggactca tcatcaataa acactgttac agcaatttgt ctcgaggact ctgg          654


<210>  7533
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7533

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7534
<211>  580
<212>  DNA
<213>  Homo sapiens

<400>  7534
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggaagttag caaaggtgac atcttctcgg ggggagccga gactgccttt    180

cctgtctttc cttttttctg agagattcaa agcctccacg actctgtttc ccccgtccct    240

tctgaattta atttgcacta agtcatttgc actggttgga gttgtggaga cggccttgag    300

tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc agggcccggc    360

cgccctccat ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc    420

ctcgcctagt ctggaagctc cgaccgacat cacggagcag ccttcaagca ttccattacg    480

ccccatctcg ctctgtgccc ctccccacca gggcttcagc aggagccctg gactcatcat    540

caataaacac tgttacagca atttgtctcg aggactctgg                          580


<210>  7535
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7535

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Glu Val Ser Lys Gly Asp Ile Phe Ser Gly Gly 
            20                  25                  30


Ala Glu Thr Ala Phe Pro Val Phe Pro Phe Phe 
        35                  40


<210>  7536
<211>  1901
<212>  DNA
<213>  Homo sapiens

<400>  7536
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggaagttag caaaggtgac atcttctcgg ggggagccga gactgcgcaa    180

ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg agggagcaca    240

ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg tcagacaggg    300

acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca ccgcaattca    360

tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg ccggagcctc    420

gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga cgtcaccagg    480

agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga ggctgcaggg    540

gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg tgcggagagg    600

gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg ggctggcttg    660

gcagacagta cagcatccag gggagtcaag ggcatggggc gagaccagac taggcgaggc    720

gggcggggcg gagtgaatga gctctcagga gggaggatgg tgcaggcagg ggtgaggagc    780

gcagcgggcg gcgagcggga ggcactggcc tccagagccc gtggccaagg cgggcctcgc    840

gggcggcgac ggagccggga tcggtgcctc agcgttcggg ctggagacga ggccaggtct    900

ccagctgggg tggacgtgcc caccagctgc cgaaggccaa gacgccaggt ccggtggacg    960

tgacaagcag gacatgacat ggtccggtgt gacggcgagg acagaggagg cgcgtccggc   1020

cttcctgaac accttaggct ggtggggctg cggcaagaag cgggtctgtt tctttacttc   1080

ctccacggag tcggcacact atggctgccc tctgggctcc cagaacccac aacatgaaag   1140

aaatggtgct acccagctca agcctgggcc tttgaatccg gacacaaaac cctctagctt   1200

ggaaatgaat atgctgcact ttacaaccac tgcactacct gactcaggaa tcggctctgg   1260

aaggtgaagc tagaggaacc agacctcatc agcccaacat caaagacacc atcggaacag   1320

cagcgcccgc agcacccacc ccgcaccggc gactccatct tcatggccac cccctgcggc   1380

ggacggttga ccaccagcca ccacatcatc ccagagctga gctcctccag cgggatgacg   1440

ccgtccccac cacctccctc ttcttctttt tcatccttct gtctctttgt ttctgagctt   1500

tcctgtcttt ccttttttct gagagattca aagcctccac gactctgttt cccccgtccc   1560

ttctgaattt aatttgcact aagtcatttg cactggttgg agttgtggag acggccttga   1620

gtctcagtac gagtgtgcgt gagtgtgagc caccttggca agtgcctgtg cagggcccgg   1680

ccgccctcca tctgggccgg gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc   1740

cctcgcctag tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac   1800

gccccatctc gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca   1860

tcaataaaca ctgttacagc aatttgtctc gaggactctg g                       1901


<210>  7537
<211>  297
<212>  PRT
<213>  Homo sapiens

<400>  7537

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Glu Val Ser Lys Gly Asp Ile Phe Ser Gly Gly 
            20                  25                  30


Ala Glu Thr Ala Gln Gly Trp Gly Val Met Gly Pro Phe Gln Ala Glu 
        35                  40                  45


Arg Ala Arg Gly Gln Gly Gly Ser Thr Gly Val Ala Ser Val Gly Ser 
    50                  55                  60


Ser Thr Trp Gly Gly Thr Pro Gly Leu Gly Gln Thr Gly Thr Trp Gln 
65                  70                  75                  80


Gly Thr Gln Asp Arg Gly Val Pro Ser Cys His Leu Thr His Arg Asn 
                85                  90                  95


Ser Phe Ser Ser Arg His Arg Gly Ser Ser Gly Thr Ala Phe Ser Gly 
            100                 105                 110


Leu Cys Arg Ser Leu Glu Gly Trp Arg Ala Gly Arg Gln Ala Val Leu 
        115                 120                 125


Gly Glu Leu Gln Gln Asp Val Thr Arg Arg Ala Lys Arg Pro Arg Glu 
    130                 135                 140


Gly Gly Pro Gly Thr Leu Arg Ser Lys Glu Ala Ala Gly Ala Arg Pro 
145                 150                 155                 160


Ala Gly Ala Gly Pro Thr Arg His Cys Gly Pro Gly Ser Gly Ala Glu 
                165                 170                 175


Arg Ala His Ser Gly Leu Gly Asp Ala Val Cys Pro His Arg Ser Ala 
            180                 185                 190


Pro Gly Ala Gly Leu Ala Asp Ser Thr Ala Ser Arg Gly Val Lys Gly 
        195                 200                 205


Met Gly Arg Asp Gln Thr Arg Arg Gly Gly Arg Gly Gly Val Asn Glu 
    210                 215                 220


Leu Ser Gly Gly Arg Met Val Gln Ala Gly Val Arg Ser Ala Ala Gly 
225                 230                 235                 240


Gly Glu Arg Glu Ala Leu Ala Ser Arg Ala Arg Gly Gln Gly Gly Pro 
                245                 250                 255


Arg Gly Arg Arg Arg Ser Arg Asp Arg Cys Leu Ser Val Arg Ala Gly 
            260                 265                 270


Asp Glu Ala Arg Ser Pro Ala Gly Val Asp Val Pro Thr Ser Cys Arg 
        275                 280                 285


Arg Pro Arg Arg Gln Val Arg Trp Thr 
    290                 295


<210>  7538
<211>  1576
<212>  DNA
<213>  Homo sapiens

<400>  7538
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggattgcag caggacgtca ccaggagggc gaagcggcca cgggaggggg    180

gccccgggac attgcgcagc aaggaggctg caggggctcg gcctgcgggc gccggtccca    240

cgaggcactg cggcccaggg tctggtgcgg agagggccca cagtggactt ggtgacgctg    300

tatgccctca ccgctcagcc cctggggctg gcttggcaga cagtacagca tccaggggag    360

tcaagggcat ggggcgagac cagactaggc gaggcgggcg gggcggagtg aatgagctct    420

caggagggag gatggtgcag gcaggggtga ggagcgcagc gggcggcgag cgggaggcac    480

tggcctccag agcccgtggc caaggcgggc ctcgcgggcg gcgacggagc cgggatcggt    540

gcctcagcgt tcgggctgga gacgaggcca ggtctccagc tggggtggac gtgcccacca    600

gctgccgaag gccaagacgc caggtccggt ggacgtgaca agcaggacat gacatggtcc    660

ggtgtgacgg cgaggacaga ggaggcgcgt ccggccttcc tgaacacctt aggctggtgg    720

ggctgcggca agaagcgggt ctgtttcttt acttcctcca cggagtcggc acactatggc    780

tgccctctgg gctcccagaa cccacaacat gaaagaaatg gtgctaccca gctcaagcct    840

gggcctttga atccggacac aaaaccctct agcttggaaa tgaatatgct gcactttaca    900

accactgcac tacctgactc aggaatcggc tctggaaggt gaagctagag gaaccagacc    960

tcatcagccc aacatcaaag acaccatcgg aacagcagcg cccgcagcac ccaccccgca   1020

ccggcgactc catcttcatg gccaccccct gcggcggacg gttgaccacc agccaccaca   1080

tcatcccaga gctgagctcc tccagcggga tgacgccgtc cccaccacct ccctcttctt   1140

ctttttcatc cttctgtctc tttgtttctg agctttcctg tctttccttt tttctgagag   1200

attcaaagcc tccacgactc tgtttccccc gtcccttctg aatttaattt gcactaagtc   1260

atttgcactg gttggagttg tggagacggc cttgagtctc agtacgagtg tgcgtgagtg   1320

tgagccacct tggcaagtgc ctgtgcaggg cccggccgcc ctccatctgg gccgggtgac   1380

tgggcgccgg ctgtgtgccc gaggcctcac cctgccctcg cctagtctgg aagctccgac   1440

cgacatcacg gagcagcctt caagcattcc attacgcccc atctcgctct gtgcccctcc   1500

ccaccagggc ttcagcagga gccctggact catcatcaat aaacactgtt acagcaattt   1560

gtctcgagga ctctgg                                                   1576


<210>  7539
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7539

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Asp Cys Ser Arg Thr Ser Pro Gly Gly Arg Ser 
            20                  25                  30


Gly His Gly Arg Gly Ala Pro Gly His Cys Ala Ala Arg Arg Leu Gln 
        35                  40                  45


Gly Leu Gly Leu Arg Ala Pro Val Pro Arg Gly Thr Ala Ala Gln Gly 
    50                  55                  60


Leu Val Arg Arg Gly Pro Thr Val Asp Leu Val Thr Leu Tyr Ala Leu 
65                  70                  75                  80


Thr Ala Gln Pro Leu Gly Leu Ala Trp Gln Thr Val Gln His Pro Gly 
                85                  90                  95


Glu Ser Arg Ala Trp Gly Glu Thr Arg Leu Gly Glu Ala Gly Gly Ala 
            100                 105                 110


Glu 



<210>  7540
<211>  673
<212>  DNA
<213>  Homo sapiens

<400>  7540
agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa ccgaggggca     60

accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca ccttggacat    120

ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagc caccacatca    180

tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt    240

tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt    300

caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt    360

tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga    420

gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg    480

gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga    540

catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca    600

ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca gcaatttgtc    660

tcgaggactc tgg                                                       673


<210>  7541
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7541

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Pro Pro His His Pro Arg 
1               5                   10                  15


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
            20                  25                  30


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
        35                  40


<210>  7542
<211>  2108
<212>  DNA
<213>  Homo sapiens

<400>  7542
gagggagggg gtgggatggg tggggggtaa cgggggaaac tggggaagtg gggaaccgag     60

gggcaaccag gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg    120

gacatctgga gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg    180

tggggcctga ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg    240

acatcagctg gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc    300

atcccggtca cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc    360

agggtttgat cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg    420

accccatctg ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct    480

gaaagaagga ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag    540

aggggcagga tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga    600

ctgcgcaagg ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag    660

ggagcacagg ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc    720

agacagggac atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc    780

gcaattcatt tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc    840

ggagcctcga gggctggaga gcgggaagac aggcatacag catccagggg agtcaagggc    900

atggggcgag accagactag gcgaggcggg cggggcggag tgaatgagct ctcaggaggg    960

aggatggtgc aggcaggggt gaggagcgca gcgggcggcg agcgggaggc actggcctcc   1020

agagcccgtg gccaaggcgg gcctcgcggg cggcgacgga gccgggatcg gtgcctcagc   1080

gttcgggctg gagacgaggc caggtctcca gctggggtgg acgtgcccac cagctgccga   1140

aggccaagac gccaggtccg gtggacgtga caagcaggac atgacatggt ccggtgtgac   1200

ggcgaggaca gaggaggcgc gtccggcctt cctgaacacc ttaggctggt ggggctgcgg   1260

caagaagcgg gtctgtttct ttacttcctc cacggagtcg gcacactatg gctgccctct   1320

gggctcccag aacccacaac atgaaagaaa tggtgctacc cagctcaagc ctgggccttt   1380

gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta caaccactgc   1440

actacctgac tcaggaatcg gctctggaag gtgaagctag aggaaccaga cctcatcagc   1500

ccaacatcaa agacaccatc ggaacagcag cgcccgcagc acccaccccg caccggcgac   1560

tccatcttca tggccacccc ctgcggcgga cggttgacca ccagccacca catcatccca   1620

gagctgagct cctccagcgg gatgacgccg tccccaccac ctccctcttc ttctttttca   1680

tccttctgtc tctttgtttc tgagctttcc tgtctttcct tttttctgag agattcaaag   1740

cctccacgac tctgtttccc ccgtcccttc tgaatttaat ttgcactaag tcatttgcac   1800

tggttggagt tgtggagacg gccttgagtc tcagtacgag tgtgcgtgag tgtgagccac   1860

cttggcaagt gcctgtgcag ggcccggccg ccctccatct gggccgggtg actgggcgcc   1920

ggctgtgtgc ccgaggcctc accctgccct cgcctagtct ggaagctccg accgacatca   1980

cggagcagcc ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct ccccaccagg   2040

gcttcagcag gagccctgga ctcatcatca ataaacactg ttacagcaat ttgtctcgag   2100

gactctgg                                                            2108


<210>  7543
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  7543

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Tyr Ser Ile Gln Gly Ser Gln Gly His Gly Ala 
                85                  90                  95


Arg Pro Asp 



<210>  7544
<211>  1998
<212>  DNA
<213>  Homo sapiens

<400>  7544
gtgagggagg gggtgggatg ggtggggggt aacgggggaa actggggaag tggggaaccg     60

aggggcaacc aggggaagat ggggtgctgg aggagagctt gtgggagcca aggagcacct    120

tggacatctg gagtctggca ggagtgatga cgggtggagg ggctagctcg aggcagggct    180

ggtggggcct gaggccagtg aggagtgtgg agtaggcgcc caggcatcgt gcagacaggg    240

cgacatcagc tggggacgat gggcctgagc tagggctgga aagaaggggg agccaggcat    300

tcatcccggt cacttttggt tacaggacgt ggcagctggt tggacgaggg gagctggtgg    360

gcagggtttg atcccagggc ctgggcaacg gaggtgtagc tggcagcagc gggcaggtga    420

ggaccccatc tgccgggcag gtgagtccct tccctcccca ggcctcgctt ccccagcctt    480

ctgaaagaag gaggtttagg ggatcgaggg ctggcgggga gaagcagaca ccctcccagc    540

agaggggcag gatgggggca ggagagttag caaaggtgac atcttctcgg ggggagccga    600

gactgcgcaa ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg    660

agggagcaca ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg    720

tcagacaggg acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca    780

ccgcaattca tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg    840

ccggagcctc gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga    900

cgtcaccagg agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga    960

ggctgcaggg gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg   1020

tgcggagagg gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg   1080

ggctggcttg gcagacagta cagtccggtg gacgtgacaa gcagaacacc ttaggctggt   1140

ggggctgcgg caagaagcgg gtctgtttct ttacttcctc cacggagtcg gcacactatg   1200

gctgccctct gggctcccag aacccacaac atgaaagaaa tggtgctacc cagctcaagc   1260

ctgggccttt gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta   1320

caaccactgc actacctgac tcaggaatcg gctctggaag gtgaagctag aggaaccaga   1380

cctcatcagc ccaacatcaa agacaccatc ggaacagcag cgcccgcagc acccaccccg   1440

caccggcgac tccatcttca tggccacccc ctgcggcgga cggttgacca ccagccacca   1500

catcatccca gagctgagct cctccagcgg gatgacgccg tccccaccac ctccctcttc   1560

ttctttttca tccttctgtc tctttgtttc tgagctttcc tgtctttcct tttttctgag   1620

agattcaaag cctccacgac tctgtttccc ccgtcccttc tgaatttaat ttgcactaag   1680

tcatttgcac tggttggagt tgtggagacg gccttgagtc tcagtacgag tgtgcgtgag   1740

tgtgagccac cttggcaagt gcctgtgcag ggcccggccg ccctccatct gggccgggtg   1800

actgggcgcc ggctgtgtgc ccgaggcctc accctgccct cgcctagtct ggaagctccg   1860

accgacatca cggagcagcc ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct   1920

ccccaccagg gcttcagcag gagccctgga ctcatcatca ataaacactg ttacagcaat   1980

ttgtctcgag gactctgg                                                 1998


<210>  7545
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  7545

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Val Arg Trp Thr 



<210>  7546
<211>  1624
<212>  DNA
<213>  Homo sapiens

<400>  7546
gtgagggagg gggtgggatg ggtggggggt aacgggggaa actggggaag tggggaaccg     60

aggggcaacc aggggaagat ggggtgctgg aggagagctt gtgggagcca aggagcacct    120

tggacatctg gagtctggca ggagtgatga cgggtggagg ggctagctcg aggcagggct    180

ggtggggcct gaggccagtg aggagtgtgg agtaggcgcc caggcatcgt gcagacaggg    240

cgacatcagc tggggacgat gggcctgagc tagggctgga aagaaggggg agccaggcat    300

tcatcccggt cacttttggt tacaggacgt ggcagctggt tggacgaggg gagctggtgg    360

gcagggtttg atcccagggc ctgggcaacg gaggtgtagc tggcagcagc gggcaggtga    420

ggaccccatc tgccgggcag gtgagtccct tccctcccca ggcctcgctt ccccagcctt    480

ctgaaagaag gaggtttagg ggatcgaggg ctggcgggga gaagcagaca ccctcccagc    540

agaggggcag gatgggggca ggagagttag caaaggtgac atcttctcgg ggggagccga    600

gactgcgcaa ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg    660

agggagcaca ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg    720

tcagacaggg acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca    780

ccgcaattca tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg    840

ccggagcctc gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga    900

cgtcaccagg agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga    960

ggctgcaggg gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg   1020

tgcggagagg gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg   1080

ggctggcttg gcagacagta cagcatccag gggagtcaag ggcatggggc gagaccaagc   1140

tgagctcctc cagcgggatg acgccgtccc caccacctcc ctcttcttct ttttcatcct   1200

tctgtctctt tgtttctgag ctttcctgtc tttccttttt tctgagagat tcaaagcctc   1260

cacgactctg tttcccccgt cccttctgaa tttaatttgc actaagtcat ttgcactggt   1320

tggagttgtg gagacggcct tgagtctcag tacgagtgtg cgtgagtgtg agccaccttg   1380

gcaagtgcct gtgcagggcc cggccgccct ccatctgggc cgggtgactg ggcgccggct   1440

gtgtgcccga ggcctcaccc tgccctcgcc tagtctggaa gctccgaccg acatcacgga   1500

gcagccttca agcattccat tacgccccat ctcgctctgt gcccctcccc accagggctt   1560

cagcaggagc cctggactca tcatcaataa acactgttac agcaatttgt ctcgaggact   1620

ctgg                                                                1624


<210>  7547
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  7547

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Ala Glu Leu Leu 
                165                 170                 175


Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe Phe Phe Phe Ile 
            180                 185                 190


Leu Leu Ser Leu Cys Phe 
        195


<210>  7548
<211>  1622
<212>  DNA
<213>  Homo sapiens

<400>  7548
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgtcacc aggagggcga agcggccacg ggaggggggc cccgggacat tgcgcagcaa    960

ggaggctgca ggggctcggc ctgcgggcgc cggtcccacg aggcactgcg gcccagggtc   1020

tggtgcggag agggcccaca gtggacttgg tgacgctgta tgccctcacc gctcagcccc   1080

tggggctggc ttggcagaca gtacagcatc caggggagtc aagggcatgg ggcgagacca   1140

gactaggcga ggcgggcggg gcggagtgaa tgagctccct cttcttcttt ttcatccttc   1200

tgtctctttg tttctgagct ttcctgtctt tccttttttc tgagagattc aaagcctcca   1260

cgactctgtt tcccccgtcc cttctgaatt taatttgcac taagtcattt gcactggttg   1320

gagttgtgga gacggccttg agtctcagta cgagtgtgcg tgagtgtgag ccaccttggc   1380

aagtgcctgt gcagggcccg gccgccctcc atctgggccg ggtgactggg cgccggctgt   1440

gtgcccgagg cctcaccctg ccctcgccta gtctggaagc tccgaccgac atcacggagc   1500

agccttcaag cattccatta cgccccatct cgctctgtgc ccctccccac cagggcttca   1560

gcaggagccc tggactcatc atcaataaac actgttacag caatttgtct cgaggactct   1620

gg                                                                  1622


<210>  7549
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  7549

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Pro Leu Leu Leu Phe His Pro Ser 
            180                 185                 190


Val Ser Leu Phe Leu Ser Phe Pro Val Phe Pro Phe Phe 
        195                 200                 205


<210>  7550
<211>  975
<212>  DNA
<213>  Homo sapiens

<400>  7550
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggaaaatgg tgctacccag ctcaagcctg    240

ggcctttgaa tccggacaca aaaccctcta gcttggaaat gaatatgctg cactttacaa    300

ccactgcact acctgactca ggaatcggct ctggaaggtg aagctagagg aaccagacct    360

catcagccca acatcaaaga caccatcgga acagcagcgc ccgcagcacc caccccgcac    420

cggcgactcc atcttcatgg ccaccccctg cggcggacgg ttgaccacca gccaccacat    480

catcccagag ctgagctcct ccagcgggat gacgccgtcc ccaccacctc cctcttcttc    540

tttttcatcc ttctgtctct ttgtttctga gctttcctgt ctttcctttt ttctgagaga    600

ttcaaagcct ccacgactct gtttcccccg tcccttctga atttaatttg cactaagtca    660

tttgcactgg ttggagttgt ggagacggcc ttgagtctca gtacgagtgt gcgtgagtgt    720

gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc tccatctggg ccgggtgact    780

gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc ctagtctgga agctccgacc    840

gacatcacgg agcagccttc aagcattcca ttacgcccca tctcgctctg tgcccctccc    900

caccagggct tcagcaggag ccctggactc atcatcaata aacactgtta cagcaatttg    960

tctcgaggac tctgg                                                     975


<210>  7551
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  7551

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Gly Trp Trp Gly Leu Arg 
1               5                   10                  15


Pro Val Arg Ser Val Glu Asn Gly Ala Thr Gln Leu Lys Pro Gly Pro 
            20                  25                  30


Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met Leu His 
        35                  40                  45


Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly Arg 
    50                  55                  60


<210>  7552
<211>  2113
<212>  DNA
<213>  Homo sapiens

<400>  7552
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggaggtt tgatcccagg gcctgggcaa cggaggtgta    180

gctggcagca gcgggcaggt gaggacccca tctgccgggc aggtgagtcc cttccctccc    240

caggcctcgc ttccccagcc ttctgaaaga aggaggttta ggggatcgag ggctggcggg    300

gagaagcaga caccctccca gcagaggggc aggatggggg caggagagtt agcaaaggtg    360

acatcttctc ggggggagcc gagactgcgc aaggctgggg ggttatgggc ccgttccagg    420

cagaaagagc aagagggcag ggagggagca caggggtggc cagcgtaggg tccagcacgt    480

ggggtggtac cccaggcctg ggtcagacag ggacatggca ggggacacag gacagagggg    540

tccccagctg ccacctcacc caccgcaatt catttagtag caggcacagg ggcagctccg    600

gcacggcttt ctcaggccta tgccggagcc tcgagggctg gagagcggga agacaggcag    660

tgctcgggga gttgcagcag gacgtcacca ggagggcgaa gcggccacgg gaggggggcc    720

ccgggacatt gcgcagcaag gaggctgcag gggctcggcc tgcgggcgcc ggtcccacga    780

ggcactgcgg cccagggtct ggtgcggaga gggcccacag tggacttggt gacgctgtat    840

gccctcaccg ctcagcccct ggggctggct tggcagacag tacagcatcc aggggagtca    900

agggcatggg gcgagaccag actaggcgag gcgggcgggg cggagtgaat gagctctcag    960

gagggaggat ggtgcaggca ggggtgagga gcgcagcggg cggcgagcgg gaggcactgg   1020

cctccagagc ccgtggccaa ggcgggcctc gcgggcggcg acggagccgg gatcggtgcc   1080

tcagcgttcg ggctggagac gaggccaggt ctccagctgg ggtggacgtg cccaccagct   1140

gccgaaggcc aagacgccag gtccggtgga cgtgacaagc aggacatgac atggtccggt   1200

gtgacggcga ggacagagga ggcgcgtccg gccttcctga acaccttagg ctggtggggc   1260

tgcggcaaga agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc   1320

cctctgggct cccagaaccc acaacatgaa agaaatggtg ctacccagct caagcctggg   1380

cctttgaatc cggacacaaa accctctagc ttggaaatga atatgctgca ctttacaacc   1440

actgcactac ctgactcagg aatcggctct ggaaggtgaa gctagaggaa ccagacctca   1500

tcagcccaac atcaaagaca ccatcggaac agcagcgccc gcagcaccca ccccgcaccg   1560

gcgactccat cttcatggcc accccctgcg gcggacggtt gaccaccagc caccacatca   1620

tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt   1680

tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt   1740

caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt   1800

tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga   1860

gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg   1920

gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga   1980

catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca   2040

ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca gcaatttgtc   2100

tcgaggactc tgg                                                      2113


<210>  7553
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7553

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7554
<211>  1203
<212>  DNA
<213>  Homo sapiens

<400>  7554
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagacgtg cccaccagct gccgaaggcc    240

aagacgccag gtccggtgga cgtgacaagc aggacatgac atggtccggt gtgacggcga    300

ggacagagga ggcgcgtccg gccttcctga acaccttagg ctggtggggc tgcggcaaga    360

agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc cctctgggct    420

cccagaaccc acaacatgaa agaaatggtg ctacccagct caagcctggg cctttgaatc    480

cggacacaaa accctctagc ttggaaatga atatgctgca ctttacaacc actgcactac    540

ctgactcagg aatcggctct ggaaggtgaa gctagaggaa ccagacctca tcagcccaac    600

atcaaagaca ccatcggaac agcagcgccc gcagcaccca ccccgcaccg gcgactccat    660

cttcatggcc accccctgcg gcggacggtt gaccaccagc caccacatca tcccagagct    720

gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt tttcatcctt    780

ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt caaagcctcc    840

acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt tgcactggtt    900

ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga gccaccttgg    960

caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg gcgccggctg   1020

tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga catcacggag   1080

cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca ccagggcttc   1140

agcaggagcc ctggactcat catcaataaa cactgttaca gcaatttgtc tcgaggactc   1200

tgg                                                                 1203


<210>  7555
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  7555

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Gly Trp Trp Gly Leu Arg 
1               5                   10                  15


Pro Val Arg Ser Val Glu Thr Cys Pro Pro Ala Ala Glu Gly Gln Asp 
            20                  25                  30


Ala Arg Ser Gly Gly Arg Asp Lys Gln Asp Met Thr Trp Ser Gly Val 
        35                  40                  45


Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala Phe Leu Asn Thr Leu Gly 
    50                  55                  60


Trp Trp Gly Cys Gly Lys Lys Arg Val Cys Phe Phe Thr Ser Ser Thr 
65                  70                  75                  80


Glu Ser Ala His Tyr Gly Cys Pro Leu Gly Ser Gln Asn Pro Gln His 
                85                  90                  95


Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro Gly Pro Leu Asn Pro Asp 
            100                 105                 110


Thr Lys Pro Ser Ser Leu Glu Met Asn Met Leu His Phe Thr Thr Thr 
        115                 120                 125


Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly Arg 
    130                 135


<210>  7556
<211>  1895
<212>  DNA
<213>  Homo sapiens

<400>  7556
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgtcacc aggagggcga agcggccacg ggaggggggc cccgggacat tgcgcagcaa    960

ggaggctgca ggggctcggc ctgcgggcgc cggtcccacg aggcactgcg gcccagggtc   1020

tggtgcggag agggcccaca gtggacttgg tgacgctgta tgccctcacc gctcagcccc   1080

tggggctggc ttggcagaca gtacagcatc caggggaaac ccacaacatg aaagaaatgg   1140

tgctacccag ctcaagcctg ggcctttgaa tccggacaca aaaccctcta gcttggaaat   1200

gaatatgctg cactttacaa ccactgcact acctgactca ggaatcggct ctggaaggtg   1260

aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga acagcagcgc   1320

ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg cggcggacgg   1380

ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat gacgccgtcc   1440

ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga gctttcctgt   1500

ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg tcccttctga   1560

atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc ttgagtctca   1620

gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc   1680

tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc   1740

ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca ttacgcccca   1800

tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc atcatcaata   1860

aacactgtta cagcaatttg tctcgaggac tctgg                              1895


<210>  7557
<211>  211
<212>  PRT
<213>  Homo sapiens

<400>  7557

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu 
                165                 170                 175


Lys Pro Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met 
            180                 185                 190


Asn Met Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly 
        195                 200                 205


Ser Gly Arg 
    210


<210>  7558
<211>  741
<212>  DNA
<213>  Homo sapiens

<400>  7558
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagagctga gctcctccag cgggatgacg ccgtccccac cacctccctc    300

ttcttctttt tcatccttct gtctctttgt ttctgagctt tcctgtcttt ccttttttct    360

gagagattca aagcctccac gactctgttt cccccgtccc ttctgaattt aatttgcact    420

aagtcatttg cactggttgg agttgtggag acggccttga gtctcagtac gagtgtgcgt    480

gagtgtgagc caccttggca agtgcctgtg cagggcccgg ccgccctcca tctgggccgg    540

gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc cctcgcctag tctggaagct    600

ccgaccgaca tcacggagca gccttcaagc attccattac gccccatctc gctctgtgcc    660

cctccccacc agggcttcag caggagccct ggactcatca tcaataaaca ctgttacagc    720

aatttgtctc gaggactctg g                                              741


<210>  7559
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7559

Met Thr Pro Ser Pro Pro Pro Pro Ser Ser Ser Phe Ser Ser Phe Cys 
1               5                   10                  15


Leu Phe Val Ser Glu Leu Ser Cys Leu Ser Phe Phe Leu Arg Asp Ser 
            20                  25                  30


Lys Pro Pro Arg Leu Cys Phe Pro Arg Pro Phe 
        35                  40


<210>  7560
<211>  863
<212>  DNA
<213>  Homo sapiens

<400>  7560
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagagaca ccatcggaac agcagcgccc gcagcaccca    300

ccccgcaccg gcgactccat cttcatggcc accccctgcg gcggacggtt gaccaccagc    360

caccacatca tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc    420

tcttcttctt tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt    480

ctgagagatt caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca    540

ctaagtcatt tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc    600

gtgagtgtga gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc    660

gggtgactgg gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag    720

ctccgaccga catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg    780

cccctcccca ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca    840

gcaatttgtc tcgaggactc tgg                                            863


<210>  7561
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7561

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7562
<211>  1010
<212>  DNA
<213>  Homo sapiens

<400>  7562
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcatt tacaaccact gcactacctg actcaggaat    360

cggctctgga aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca    420

tcggaacagc agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc    480

ccctgcggcg gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc    540

gggatgacgc cgtccccacc acctccctct tcttcttttt catccttctg tctctttgtt    600

tctgagcttt cctgtctttc cttttttctg agagattcaa agcctccacg actctgtttc    660

ccccgtccct tctgaattta atttgcacta agtcatttgc actggttgga gttgtggaga    720

cggccttgag tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc    780

agggcccggc cgccctccat ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc    840

tcaccctgcc ctcgcctagt ctggaagctc cgaccgacat cacggagcag ccttcaagca    900

ttccattacg ccccatctcg ctctgtgccc ctccccacca gggcttcagc aggagccctg    960

gactcatcat caataaacac tgttacagca atttgtctcg aggactctgg              1010


<210>  7563
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7563

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7564
<211>  1831
<212>  DNA
<213>  Homo sapiens

<400>  7564
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctgcc acctcaccca ccgcaattca tttagtagca    300

ggcacagggg cagctccggc acggctttct caggcctatg ccggagcctc gagggctgga    360

gagcgggaag acaggcagtg ctcggggagt tgcagcagga cgtcaccagg agggcgaagc    420

ggccacggga ggggggcccc gggacattgc gcagcaagga ggctgcaggg gctcggcctg    480

cgggcgccgg tcccacgagg cactgcggcc cagggtctgg tgcggagagg gcccacagtg    540

gacttggtga cgctgtatgc cctcaccgct cagcccctgg ggctggcttg gcagacagta    600

cagcatccag gggagtcaag ggcatggggc gagaccagac taggcgaggc gggcggggcg    660

gagtgaatga gctctcagga gggaggatgg tgcaggcagg ggtgaggagc gcagcgggcg    720

gcgagcggga ggcactggcc tccagagccc gtggccaagg cgggcctcgc gggcggcgac    780

ggagccggga tcggtgcctc agcgttcggg ctggagacga ggccaggtct ccagctgggg    840

tggacgtgcc caccagctgc cgaaggccaa gacgccaggt ccggtggacg tgacaagcag    900

gacatgacat ggtccggtgt gacggcgagg acagaggagg cgcgtccggc cttcctgaac    960

accttaggct ggtggggctg cggcaagaag cgggtctgtt tctttacttc ctccacggag   1020

tcggcacact atggctgccc tctgggctcc cagaacccac aacatgaaag aaatggtgct   1080

acccagctca agcctgggcc tttgaatccg gacacaaaac cctctagctt ggaaatgaat   1140

atgctgcact ttacaaccac tgcactacct gactcaggaa tcggctctgg aaggtgaagc   1200

tagaggaacc agacctcatc agcccaacat caaagacacc atcggaacag cagcgcccgc   1260

agcacccacc ccgcaccggc gactccatct tcatggccac cccctgcggc ggacggttga   1320

ccaccagcca ccacatcatc ccagagctga gctcctccag cgggatgacg ccgtccccac   1380

cacctccctc ttcttctttt tcatccttct gtctctttgt ttctgagctt tcctgtcttt   1440

ccttttttct gagagattca aagcctccac gactctgttt cccccgtccc ttctgaattt   1500

aatttgcact aagtcatttg cactggttgg agttgtggag acggccttga gtctcagtac   1560

gagtgtgcgt gagtgtgagc caccttggca agtgcctgtg cagggcccgg ccgccctcca   1620

tctgggccgg gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc cctcgcctag   1680

tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac gccccatctc   1740

gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca tcaataaaca   1800

ctgttacagc aatttgtctc gaggactctg g                                  1831


<210>  7565
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7565

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7566
<211>  1699
<212>  DNA
<213>  Homo sapiens

<400>  7566
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcact tttggttaca ggacgtggca gctggttgga    360

cgaggggagc tggtgggcag gggtctggtg cggagagggc ccacagtgga cttggtgacg    420

ctgtatgccc tcaccgctca gcccctgggg ctggcttggc agacagtaca gcatccaggg    480

gagtcaaggg catggggcga gaccagacta ggcgaggcgg gcggggcgga gtgaatgagc    540

tctcaggagg gaggatggtg caggcagggg tgaggagcgc agcgggcggc gagcgggagg    600

cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg gcggcgacgg agccgggatc    660

ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc agctggggtg gacgtgccca    720

ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg acaagcagga catgacatgg    780

tccggtgtga cggcgaggac agaggaggcg cgtccggcct tcctgaacac cttaggctgg    840

tggggctgcg gcaagaagcg ggtctgtttc tttacttcct ccacggagtc ggcacactat    900

ggctgccctc tgggctccca gaacccacaa catgaaagaa atggtgctac ccagctcaag    960

cctgggcctt tgaatccgga cacaaaaccc tctagcttgg aaatgaatat gctgcacttt   1020

acaaccactg cactacctga ctcaggaatc ggctctggaa ggtgaagcta gaggaaccag   1080

acctcatcag cccaacatca aagacaccat cggaacagca gcgcccgcag cacccacccc   1140

gcaccggcga ctccatcttc atggccaccc cctgcggcgg acggttgacc accagccacc   1200

acatcatccc agagctgagc tcctccagcg ggatgacgcc gtccccacca cctccctctt   1260

cttctttttc atccttctgt ctctttgttt ctgagctttc ctgtctttcc ttttttctga   1320

gagattcaaa gcctccacga ctctgtttcc cccgtccctt ctgaatttaa tttgcactaa   1380

gtcatttgca ctggttggag ttgtggagac ggccttgagt ctcagtacga gtgtgcgtga   1440

gtgtgagcca ccttggcaag tgcctgtgca gggcccggcc gccctccatc tgggccgggt   1500

gactgggcgc cggctgtgtg cccgaggcct caccctgccc tcgcctagtc tggaagctcc   1560

gaccgacatc acggagcagc cttcaagcat tccattacgc cccatctcgc tctgtgcccc   1620

tccccaccag ggcttcagca ggagccctgg actcatcatc aataaacact gttacagcaa   1680

tttgtctcga ggactctgg                                                1699


<210>  7567
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7567

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7568
<211>  808
<212>  DNA
<213>  Homo sapiens

<400>  7568
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac tccatcttca tggccacccc ctgcggcgga cggttgacca    300

ccagccacca catcatccca gagctgagct cctccagcgg gatgacgccg tccccaccac    360

ctccctcttc ttctttttca tccttctgtc tctttgtttc tgagctttcc tgtctttcct    420

tttttctgag agattcaaag cctccacgac tctgtttccc ccgtcccttc tgaatttaat    480

ttgcactaag tcatttgcac tggttggagt tgtggagacg gccttgagtc tcagtacgag    540

tgtgcgtgag tgtgagccac cttggcaagt gcctgtgcag ggcccggccg ccctccatct    600

gggccgggtg actgggcgcc ggctgtgtgc ccgaggcctc accctgccct cgcctagtct    660

ggaagctccg accgacatca cggagcagcc ttcaagcatt ccattacgcc ccatctcgct    720

ctgtgcccct ccccaccagg gcttcagcag gagccctgga ctcatcatca ataaacactg    780

ttacagcaat ttgtctcgag gactctgg                                       808


<210>  7569
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7569

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7570
<211>  2367
<212>  DNA
<213>  Homo sapiens

<400>  7570
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat    660

gggcccgttc caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt    720

agggtccagc acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac    780

acaggacaga ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca    840

caggggcagc tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc    900

gggaagacag gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc    960

acgggagggg ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg   1020

cgccggtccc acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact   1080

tggtgacgct gtatgccctc accgctcagc ccctggggct ggcttggcag acagtacagc   1140

atccagggga gtcaagggca tggggcgaga ccagactagg cgaggcgggc ggggcggagt   1200

gaatgagctc tcaggaggga ggatggtgca ggcaggggtg aggagcgcag cgggcggcga   1260

gcgggaggca ctggcctcca gagcccgtgg ccaaggcggg cctcgcgggc ggcgacggag   1320

ccgggatcgg tgcctcagcg ttcgggctgg agacgaggcc aggtctccag ctggggtgga   1380

cgtgcccacc agctgccgaa ggccaagacg ccaggtccgg tggacgtgac aagcaggaca   1440

tgacatggtc cggtgtgacg gcgaggacag aggaggcgcg tccggccttc ctgaacacct   1500

taggctggtg gggctgcggc aagaagcggg tctgtttctt tacttcctcc acggagtcgg   1560

cacactatgg ctgccctctg ggctcccaga acccacaaca tgaaagaaat ggtgctaccc   1620

agctcaagcc tgggcctttg aatccggaca caaaaccctc tagcttggaa atgaatatgc   1680

tgcactttac aaccactgca ctacctgact caggaatcgg ctctggaagg tgaagctaga   1740

ggaaccagac ctcatcagcc caacatcaaa gacaccatcg gaacagcagc gcccgcagca   1800

cccaccccgc accggcgact ccatcttcat ggccaccccc tgcggcggac ggttgaccac   1860

cagccaccac atcatcccag agctgagctc ctccagcggg atgacgccgt ccccaccacc   1920

tccctcttct tctttttcat ccttctgtct ctttgtttct gagctttcct gtctttcctt   1980

ttttctgaga gattcaaagc ctccacgact ctgtttcccc cgtcccttct gaatttaatt   2040

tgcactaagt catttgcact ggttggagtt gtggagacgg ccttgagtct cagtacgagt   2100

gtgcgtgagt gtgagccacc ttggcaagtg cctgtgcagg gcccggccgc cctccatctg   2160

ggccgggtga ctgggcgccg gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg   2220

gaagctccga ccgacatcac ggagcagcct tcaagcattc cattacgccc catctcgctc   2280

tgtgcccctc cccaccaggg cttcagcagg agccctggac tcatcatcaa taaacactgt   2340

tacagcaatt tgtctcgagg actctgg                                       2367


<210>  7571
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7571

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7572
<211>  1927
<212>  DNA
<213>  Homo sapiens

<400>  7572
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat    660

gggcccgttc caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt    720

agggtccagc acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac    780

acaggacaga ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca    840

caggggcagc tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc    900

gggaagacag gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc    960

acgggagggg ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg   1020

cgccggtccc acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact   1080

tggtgacgct gtatgccctc accgctcagc ccctggggct ggcttggcag acactgagtg   1140

ggacctcact ccttccccat ccacagaaat ggtgctaccc agctcaagcc tgggcctttg   1200

aatccggaca caaaaccctc tagcttggaa atgaatatgc tgcactttac aaccactgca   1260

ctacctgact caggaatcgg ctctggaagg tgaagctaga ggaaccagac ctcatcagcc   1320

caacatcaaa gacaccatcg gaacagcagc gcccgcagca cccaccccgc accggcgact   1380

ccatcttcat ggccaccccc tgcggcggac ggttgaccac cagccaccac atcatcccag   1440

agctgagctc ctccagcggg atgacgccgt ccccaccacc tccctcttct tctttttcat   1500

ccttctgtct ctttgtttct gagctttcct gtctttcctt ttttctgaga gattcaaagc   1560

ctccacgact ctgtttcccc cgtcccttct gaatttaatt tgcactaagt catttgcact   1620

ggttggagtt gtggagacgg ccttgagtct cagtacgagt gtgcgtgagt gtgagccacc   1680

ttggcaagtg cctgtgcagg gcccggccgc cctccatctg ggccgggtga ctgggcgccg   1740

gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg gaagctccga ccgacatcac   1800

ggagcagcct tcaagcattc cattacgccc catctcgctc tgtgcccctc cccaccaggg   1860

cttcagcagg agccctggac tcatcatcaa taaacactgt tacagcaatt tgtctcgagg   1920

actctgg                                                             1927


<210>  7573
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7573

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Thr Glu 
145                 150                 155                 160


Trp Asp Leu Thr Pro Ser Pro Ser Thr Glu Met Val Leu Pro Ser Ser 
                165                 170                 175


Ser Leu Gly Leu 
            180


<210>  7574
<211>  1580
<212>  DNA
<213>  Homo sapiens

<400>  7574
gctaatttag gagcttgaga tgctaaagag ctgggagtgc cactgctgct ttattctggg     60

gtctaggatc cttgtgttgg ctgagataat ctgctaatgt gggtgcagca gacatcccgc    120

ggtttgtgga atcgataaag gatggggatc aatggtgttt gtgcactgtg cggtctgtgc    180

ccaattgcct gccttgtgct gtggaatctg tacatctggc caacatgtgc ttgtgtgagc    240

ctgacagtgc attttccaga gcctcacctc ggctctgccc tggaggctct gtgctgctgg    300

aatcagactc aaggacctca tcagaggacc atggccccgt atcacctggg tcaggcactg    360

aagctgggac aggagagcag agacttccaa aatgagggat ccctgtgttc tgaggtgatc    420

atgactggga cccaaggact caagcgcatg ctccagaggg aatcgtttcc cacaaggcct    480

ttggcaggaa cagggatcct gggagcctgc caagcagagc gcacagtgtt cctggagtct    540

cgctgcccag atgccacgga atcagttgaa gccaggtctc cagctggggt ggacgtgccc    600

accagctgcc gaaggccaag acgccaggtc cggtggacgt gacaagcagg acatgacatg    660

gtccggtgtg acggcgagga cagaggaggc gcgtccggcc ttcctgaaca ccttaggctg    720

gtggggctgc ggcaagaagc gggtctgttt ctttacttcc tccacggagt cggcacacta    780

tggctgccct ctgggctccc agaacccaca acatgaaaga aatggtgcta cccagctcaa    840

gcctgggcct ttgaatccgg acacaaaacc ctctagcttg gaaatgaata tgctgcactt    900

tacaaccact gcactacctg actcaggaat cggctctgga aggtgaagct agaggaacca    960

gacctcatca gcccaacatc aaagacacca tcggaacagc agcgcccgca gcacccaccc   1020

cgcaccggcg actccatctt catggccacc ccctgcggcg gacggttgac caccagccac   1080

cacatcatcc cagagctgag ctcctccagc gggatgacgc cgtccccacc acctccctct   1140

tcttcttttt catccttctg tctctttgtt tctgagcttt cctgtctttc cttttttctg   1200

agagattcaa agcctccacg actctgtttc ccccgtccct tctgaattta atttgcacta   1260

agtcatttgc actggttgga gttgtggaga cggccttgag tctcagtacg agtgtgcgtg   1320

agtgtgagcc accttggcaa gtgcctgtgc agggcccggc cgccctccat ctgggccggg   1380

tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc ctcgcctagt ctggaagctc   1440

cgaccgacat cacggagcag ccttcaagca ttccattacg ccccatctcg ctctgtgccc   1500

ctccccacca gggcttcagc aggagccctg gactcatcat caataaacac tgttacagca   1560

atttgtctcg aggactctgg                                               1580


<210>  7575
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  7575

Met Gly Ile Asn Gly Val Cys Ala Leu Cys Gly Leu Cys Pro Ile Ala 
1               5                   10                  15


Cys Leu Val Leu Trp Asn Leu Tyr Ile Trp Pro Thr Cys Ala Cys Val 
            20                  25                  30


Ser Leu Thr Val His Phe Pro Glu Pro His Leu Gly Ser Ala Leu Glu 
        35                  40                  45


Ala Leu Cys Cys Trp Asn Gln Thr Gln Gly Pro His Gln Arg Thr Met 
    50                  55                  60


Ala Pro Tyr His Leu Gly Gln Ala Leu Lys Leu Gly Gln Glu Ser Arg 
65                  70                  75                  80


Asp Phe Gln Asn Glu Gly Ser Leu Cys Ser Glu Val Ile Met Thr Gly 
                85                  90                  95


Thr Gln Gly Leu Lys Arg Met Leu Gln Arg Glu Ser Phe Pro Thr Arg 
            100                 105                 110


Pro Leu Ala Gly Thr Gly Ile Leu Gly Ala Cys Gln Ala Glu Arg Thr 
        115                 120                 125


Val Phe Leu Glu Ser Arg Cys Pro Asp Ala Thr Glu Ser Val Glu Ala 
    130                 135                 140


Arg Ser Pro Ala Gly Val Asp Val Pro Thr Ser Cys Arg Arg Pro Arg 
145                 150                 155                 160


Arg Gln Val Arg Trp Thr 
                165


<210>  7576
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  7576
aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc     60

agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg    120

gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc    180

cgtccccacc acctccctct tcttcttttt catccttctg tctctttgtt tctgagcttt    240

cctgtctttc cttttttctg agagacggcc ttgagtctca gtacgagtgt gcgtgagtgt    300

gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc tccatctggg ccgggtgact    360

gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc ctagtctgga agctccgacc    420

gacatcacgg agcagccttc aagcattcca ttacgcccca tctcgctctg tgcccctccc    480

caccagggct tcagcaggag ccctggactc atcatcaata aacactgtta cagcaatttg    540

tctcgag                                                              547


<210>  7577
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  7577

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Gly Leu Glu Ser Gln Tyr Glu Cys Ala 
    50                  55                  60


<210>  7578
<211>  518
<212>  DNA
<213>  Homo sapiens

<400>  7578
aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc     60

agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg    120

gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc    180

ctcccttctg aatttaattt gcactaagtc atttgcactg gttggagttg tggagacggc    240

cttgagtctc agtacgagtg tgcgtgagtg tgagccacct tggcaagtgc ctgtgcaggg    300

cccggccgcc ctccatctgg gccgggtgac tgggcgccgg ctgtgtgccc gaggcctcac    360

cctgccctcg cctagtctgg aagctccgac cgacatcacg gagcagcctt caagcattcc    420

attacgcccc atctcgctct gtgcccctcc ccaccagggc ttcagcagga gccctggact    480

catcatcaat aaacactgtt acagcaattt gtctcgag                            518


<210>  7579
<211>  171
<212>  PRT
<213>  Homo sapiens

<400>  7579

Gly Glu Ala Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr 
1               5                   10                  15


Ile Gly Thr Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His 
            20                  25                  30


Leu His Gly His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His 
        35                  40                  45


His Pro Arg Ala Glu Leu Leu Gln Arg Asp Asp Ala Ser Leu Leu Asn 
    50                  55                  60


Leu Ile Cys Thr Lys Ser Phe Ala Leu Val Gly Val Val Glu Thr Ala 
65                  70                  75                  80


Leu Ser Leu Ser Thr Ser Val Arg Glu Cys Glu Pro Pro Trp Gln Val 
                85                  90                  95


Pro Val Gln Gly Pro Ala Ala Leu His Leu Gly Arg Val Thr Gly Arg 
            100                 105                 110


Arg Leu Cys Ala Arg Gly Leu Thr Leu Pro Ser Pro Ser Leu Glu Ala 
        115                 120                 125


Pro Thr Asp Ile Thr Glu Gln Pro Ser Ser Ile Pro Leu Arg Pro Ile 
    130                 135                 140


Ser Leu Cys Ala Pro Pro His Gln Gly Phe Ser Arg Ser Pro Gly Leu 
145                 150                 155                 160


Ile Ile Asn Lys His Cys Tyr Ser Asn Leu Ser 
                165                 170


<210>  7580
<211>  1773
<212>  DNA
<213>  Homo sapiens

<400>  7580
gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg gacatctgga     60

gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg tggggcctga    120

ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg acatcagctg    180

gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc atcccggtca    240

cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc agggtttgat    300

cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg accccatctg    360

ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct gaaagaagga    420

ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag aggggcagga    480

tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga ctgcgcaagg    540

ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag ggagcacagg    600

ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc agacagggac    660

atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc gcaattcatt    720

tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc ggagcctcga    780

gggctggaga gcgggaagac aggcagtgct cggggagttg cagcaggacg tcaccaggag    840

ggcgaagcgg ccacgggagg ggggccccgg gacattgcgc agcaaggagg ctgcaggggc    900

tcggcctgcg ggcgccggtc ccacgaggca ctgcggccca gggtctggtg cggagagggc    960

ccacagtgga cttggtgacg ctgtatgccc tcaccgctca gcccctgggg ctggcttggc   1020

agacagtaca gcatccaggg gagtcaaggg catggggcga gaccagacta ggcgaggcgg   1080

gcggggcgga gtgaatgagc tctcaggagg gaggatggtg caggcagggg tgaggagcgc   1140

agcgggcggc gagcgggagg cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg   1200

gcggcgacgg agccgggatc ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc   1260

agctggggtg gacgtgccca ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg   1320

acaagcagga catgacatgg tccggtgtga cggcgaggac agaggaggcg cgtccggcct   1380

tcctgaacac cttaggctgg tggggctgcg gcaagaagcg gactctgttt cccccgtccc   1440

ttctgaattt aatttgcact aagtcatttg cactggttgg agttgtggag acggccttga   1500

gtctcagtac gagtgtgcgt gagtgtgagc caccttggca agtgcctgtg cagggcccgg   1560

ccgccctcca tctgggccgg gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc   1620

cctcgcctag tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac   1680

gccccatctc gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca   1740

tcaataaaca ctgttacagc aatttgtctc gag                                1773


<210>  7581
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7581

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7582
<211>  347
<212>  DNA
<213>  Homo sapiens

<400>  7582
gggaaactgg ggaagtgggg aaccgagggg caaccagggg aagatggggt gctggaggag     60

agcttgtggg agccaaggag caccttggac atctggatgt gagccacctt ggcaagtgcc    120

tgtgcagggc ccggccgccc tccatctggg ccgggtgact gggcgccggc tgtgtgcccg    180

aggcctcacc ctgccctcgc ctagtctgga agctccgacc gacatcacgg agcagccttc    240

aagcattcca ttacgcccca tctcgctctg tgcccctccc caccagggct tcagcaggag    300

ccctggactc atcatcaata aacactgtta cagcaatttg tctcgag                  347


<210>  7583
<211>  100
<212>  PRT
<213>  Homo sapiens

<400>  7583

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Cys Glu Pro Pro Trp Gln Val Pro Val Gln Gly Pro Ala Ala 
            20                  25                  30


Leu His Leu Gly Arg Val Thr Gly Arg Arg Leu Cys Ala Arg Gly Leu 
        35                  40                  45


Thr Leu Pro Ser Pro Ser Leu Glu Ala Pro Thr Asp Ile Thr Glu Gln 
    50                  55                  60


Pro Ser Ser Ile Pro Leu Arg Pro Ile Ser Leu Cys Ala Pro Pro His 
65                  70                  75                  80


Gln Gly Phe Ser Arg Ser Pro Gly Leu Ile Ile Asn Lys His Cys Tyr 
                85                  90                  95


Ser Asn Leu Ser 
            100


<210>  7584
<211>  599
<212>  DNA
<213>  Homo sapiens

<400>  7584
agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa ccgaggggca     60

accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca ccttggacat    120

ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagc caccacatca    180

tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt    240

tttcatcctt ctgtctcttt gtttccttct gaatttaatt tgcactaagt catttgcact    300

ggttggagtt gtggagacgg ccttgagtct cagtacgagt gtgcgtgagt gtgagccacc    360

ttggcaagtg cctgtgcagg gcccggccgc cctccatctg ggccgggtga ctgggcgccg    420

gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg gaagctccga ccgacatcac    480

ggagcagcct tcaagcattc cattacgccc catctcgctc tgtgcccctc cccaccaggg    540

cttcagcagg agccctggac tcatcatcaa taaacactgt tacagcaatt tgtctcgag     599


<210>  7585
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  7585

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Pro Pro His His Pro Arg 
1               5                   10                  15


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
            20                  25                  30


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe Leu Leu Asn Leu Ile Cys 
        35                  40                  45


Thr Lys Ser Phe Ala Leu Val Gly Val Val Glu Thr Ala Leu Ser Leu 
    50                  55                  60


Ser Thr Ser Val Arg Glu Cys Glu Pro Pro Trp Gln Val Pro Val Gln 
65                  70                  75                  80


Gly Pro Ala Ala Leu His Leu Gly Arg Val Thr Gly Arg Arg Leu Cys 
                85                  90                  95


Ala Arg Gly Leu Thr Leu Pro Ser Pro Ser Leu Glu Ala Pro Thr Asp 
            100                 105                 110


Ile Thr Glu Gln Pro Ser Ser Ile Pro Leu Arg Pro Ile Ser Leu Cys 
        115                 120                 125


Ala Pro Pro His Gln Gly Phe Ser Arg Ser Pro Gly Leu Ile Ile Asn 
    130                 135                 140


Lys His Cys Tyr Ser Asn Leu Ser 
145                 150


<210>  7586
<211>  1456
<212>  DNA
<213>  Homo sapiens

<400>  7586
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgtcacc aggagggcga agcggccacg ggaggggggc cccgggacat tgcgcagcaa    960

ggaggctgca ggggctcggc ctgcgggcgc cggtcccacg aggcactgcg gcccagggtc   1020

tggtgcggag agggcccaca gtggacttgg tgacgctgta tgccctcacc gctcagcccc   1080

tggggctggc ttggcagaca gtacagcatc caggggagtc aagggcatgg ggcgagacca   1140

gataagtcat ttgcactggt tggagttgtg gagacggcct tgagtctcag tacgagtgtg   1200

cgtgagtgtg agccaccttg gcaagtgcct gtgcagggcc cggccgccct ccatctgggc   1260

cgggtgactg ggcgccggct gtgtgcccga ggcctcaccc tgccctcgcc tagtctggaa   1320

gctccgaccg acatcacgga gcagccttca agcattccat tacgccccat ctcgctctgt   1380

gcccctcccc accagggctt cagcaggagc cctggactca tcatcaataa acactgttac   1440

agcaatttgt ctcgag                                                   1456


<210>  7587
<211>  185
<212>  PRT
<213>  Homo sapiens

<400>  7587

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Ile Ser His Leu 
                165                 170                 175


His Trp Leu Glu Leu Trp Arg Arg Pro 
            180                 185


<210>  7588
<211>  856
<212>  DNA
<213>  Homo sapiens

<400>  7588
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa agaaatggtg    120

ctacccagct caagcctggg cctttgaatc cggacacaaa accctctagc ttggaaatga    180

atatgctgca ctttacaacc actgcactac ctgactcagg aatcggctct ggaaggtgaa    240

gctagaggaa ccagacctca tcagcccaac atcaaagaca ccatcggaac agcagcgccc    300

gcagcaccca ccccgcaccg gcgactccat cttcatggcc accccctgcg gcggacggtt    360

gaccaccagc caccacatca tcccagagct gagctcctcc agcgggatga cgccgtcccc    420

accacctccc tcttcttctt tttcatcctt ctgtctcttt gtttctgagc tttcctgtct    480

ttcctttttt ctgagagatt caaagcctcc acgactctgt ttcccccgtc ccttctgaat    540

ttaatttgca ctaagtcatt tgcactggtt ggagttgtgg agacggcctt gagtctcagt    600

acgagtgtgc gtgagtgtga gccaccttgg caagtgcctg tgcagggccc ggccgccctc    660

catctgggcc gggtgactgg gcgccggctg tgtgcccgag gcctcaccct gccctcgcct    720

agtctggaag ctccgaccga catcacggag cagccttcaa gcattccatt acgccccatc    780

tcgctctgtg cccctcccca ccagggcttc agcaggagcc ctggactcat catcaataaa    840

cactgttaca gcaatt                                                    856


<210>  7589
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7589

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7590
<211>  733
<212>  DNA
<213>  Homo sapiens

<400>  7590
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa aggtgaagct    120

agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc agcgcccgca    180

gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg gacggttgac    240

caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc cgtccccacc    300

acctccctct tcttcttttt catccttctg tctctttgtt tctgagcttt cctgtctttc    360

cttttttctg agagattcaa agcctccacg actctgtttc ccccgtccct tctgaattta    420

atttgcacta agtcatttgc actggttgga gttgtggaga cggccttgag tctcagtacg    480

agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc agggcccggc cgccctccat    540

ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc ctcgcctagt    600

ctggaagctc cgaccgacat cacggagcag ccttcaagca ttccattacg ccccatctcg    660

ctctgtgccc ctccccacca gggcttcagc aggagccctg gactcatcat caataaacac    720

tgttacagca att                                                       733


<210>  7591
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7591

Met Ala Ala Leu Trp Ala Pro Arg Thr His Asn Met Lys Gly Glu Ala 
1               5                   10                  15


Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr Ile Gly Thr 
            20                  25                  30


Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His Leu His Gly 
        35                  40                  45


His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His His Pro Arg 
    50                  55                  60


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
65                  70                  75                  80


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
                85                  90


<210>  7592
<211>  936
<212>  DNA
<213>  Homo sapiens

<400>  7592
acaccttagg ctggtggggc tgcggcaaga agcgggtctg tttctttact tcctccacgg     60

agtcggcaca ctatggctgc cctctgggct cccagaaccc acaacatgaa aggtgagggg    120

cttcctgcca cacttggggt ggggggcacg cgagaggagc tgagtgggac ctcactcctt    180

ccccatccac agaaatggtg ctacccagct caagcctggg cctttgaatc cggacacaaa    240

accctctagc ttggaaatga atatgctgca ctttacaacc actgcactac ctgactcagg    300

aatcggctct ggaaggtgaa gctagaggaa ccagacctca tcagcccaac atcaaagaca    360

ccatcggaac agcagcgccc gcagcaccca ccccgcaccg gcgactccat cttcatggcc    420

accccctgcg gcggacggtt gaccaccagc caccacatca tcccagagct gagctcctcc    480

agcgggatga cgccgtcccc accacctccc tcttcttctt tttcatcctt ctgtctcttt    540

gtttctgagc tttcctgtct ttcctttttt ctgagagatt caaagcctcc acgactctgt    600

ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt tgcactggtt ggagttgtgg    660

agacggcctt gagtctcagt acgagtgtgc gtgagtgtga gccaccttgg caagtgcctg    720

tgcagggccc ggccgccctc catctgggcc gggtgactgg gcgccggctg tgtgcccgag    780

gcctcaccct gccctcgcct agtctggaag ctccgaccga catcacggag cagccttcaa    840

gcattccatt acgccccatc tcgctctgtg cccctcccca ccagggcttc agcaggagcc    900

ctggactcat catcaataaa cactgttaca gcaatt                              936


<210>  7593
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7593

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7594
<211>  1152
<212>  DNA
<213>  Homo sapiens

<400>  7594
caggtctcca gctggggtgg acgtgcccac cagctgccga aggccaagac gccaggtccg     60

gtggacgtga caagcaggac atgacatggt ccggtgtgac ggcgaggaca gaggaggcgc    120

gtccggcctt cctgaacacc ttaggctggt ggggctgcgg caagaagcgg gtctgtttct    180

ttacttcctc cacggagtcg gcacactatg gctgccctct gggctcccag aacccacaac    240

atgaaaggtg aggggcttcc tgccacactt ggggtggggg gcacgcgaga ggagctgagt    300

gggacctcac tccttcccca tccacagaaa tggtgctacc cagctcaagc ctgggccttt    360

gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta caaccactgc    420

actacctgac tcaggaatcg gctctggaag gtgagcacca gcgctccttc cggaagcctc    480

caggcccccg agcaccctgc ccccatccca cccacgtgtc gctatctcta ggtgaagcta    540

gaggaaccag acctcatcag cccaacatca aagacaccat cggaacagca gcgcccgcag    600

cacccacccc gcaccggcga ctccatcttc atggccaccc cctgcggcgg acggttgacc    660

accagccacc acatcatccc agagctgagc tcctccagcg ggatgacgcc gtccccacca    720

cctccctctt cttctttttc atccttctgt ctctttgttt ctgagctttc ctgtctttcc    780

ttttttctga gagattcaaa gcctccacga ctctgtttcc cccgtccctt ctgaatttaa    840

tttgcactaa gtcatttgca ctggttggag ttgtggagac ggccttgagt ctcagtacga    900

gtgtgcgtga gtgtgagcca ccttggcaag tgcctgtgca gggcccggcc gccctccatc    960

tgggccgggt gactgggcgc cggctgtgtg cccgaggcct caccctgccc tcgcctagtc   1020

tggaagctcc gaccgacatc acggagcagc cttcaagcat tccattacgc cccatctcgc   1080

tctgtgcccc tccccaccag ggcttcagca ggagccctgg actcatcatc aataaacact   1140

gttacagcaa tt                                                       1152


<210>  7595
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  7595

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg 
    50                  55


<210>  7596
<211>  868
<212>  DNA
<213>  Homo sapiens

<400>  7596
caggtctcca gctggggtgg acgtgcccac cagctgccga aggccaagac gccaggtccg     60

gtggacgtga caagcaggac atgacatggt ccggtgtgac ggcgaggaca gaggaggcgc    120

gtccggcctt cctgaacacc ttaggctggt ggggctgcgg caagaagcgg gtctgtttct    180

ttacttcctc cacggagtcg gcacactatg gctgccctct gggctcccag aacccacaac    240

atgaaaggtg aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga    300

acagcagcgc ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg    360

cggcggacgg ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat    420

gacgccgtcc ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga    480

gctttcctgt ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg    540

tcccttctga atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc    600

ttgagtctca gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc    660

ccggccgccc tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc    720

ctgccctcgc ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca    780

ttacgcccca tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc    840

atcatcaata aacactgtta cagcaatt                                       868


<210>  7597
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7597

Met Ala Ala Leu Trp Ala Pro Arg Thr His Asn Met Lys Gly Glu Ala 
1               5                   10                  15


Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr Ile Gly Thr 
            20                  25                  30


Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His Leu His Gly 
        35                  40                  45


His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His His Pro Arg 
    50                  55                  60


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
65                  70                  75                  80


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
                85                  90


<210>  7598
<211>  1038
<212>  DNA
<213>  Homo sapiens

<400>  7598
acaaccaaca cgttctcccc acacgactct ctcgttctcc ccacagccag gtctccagct     60

ggggtggacg tgcccaccag ctgccgaagg ccaagacgcc aggtccggtg gacgtgacaa    120

gcaggacatg acatggtccg gtgtgacggc gaggacagag gaggcgcgtc cggccttcct    180

gaacacctta ggctggtggg gctgcggcaa gaagcgggtc tgtttcttta cttcctccac    240

ggagtcggca cactatggct gccctctggg ctcccagaac ccacaacatg aaagaaatgg    300

tgctacccag ctcaagcctg ggcctttgaa tccggacaca aaaccctcta gcttggaaat    360

gaatatgctg cactttacaa ccactgcact acctgactca ggaatcggct ctggaaggtg    420

aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga acagcagcgc    480

ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg cggcggacgg    540

ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat gacgccgtcc    600

ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga gctttcctgt    660

ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg tcccttctga    720

atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc ttgagtctca    780

gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc    840

tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc    900

ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca ttacgcccca    960

tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc atcatcaata   1020

aacactgtta cagcaatt                                                 1038


<210>  7599
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7599

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7600
<211>  2119
<212>  DNA
<213>  Homo sapiens

<400>  7600
gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg gacatctgga     60

gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg tggggcctga    120

ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg acatcagctg    180

gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc atcccggtca    240

cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc agggtttgat    300

cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg accccatctg    360

ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct gaaagaagga    420

ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag aggggcagga    480

tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga ctgcgcaagg    540

ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag ggagcacagg    600

ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc agacagggac    660

atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc gcaattcatt    720

tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc ggagcctcga    780

gggctggaga gcgggaagac aggcagtgct cggggagttg cagcaggacg tcaccaggag    840

ggcgaagcgg ccacgggagg ggggccccgg gacattgcgc agcaaggagg ctgcaggggc    900

tcggcctgcg ggcgccggtc ccacgaggca ctgcggccca gggtctggtg cggagagggc    960

ccacagtgga cttggtgacg ctgtatgccc tcaccgctca gcccctgggg ctggcttggc   1020

agacagtaca gcatccaggg gagtcaaggg catggggcga gaccagacta ggcgaggcgg   1080

gcggggcgga gtgaatgagc tctcaggagg gaggatggtg caggcagggg tgaggagcgc   1140

agcgggcggc gagcgggagg cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg   1200

gcggcgacgg agccgggatc ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc   1260

agctggggtg gacgtgccca ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg   1320

acaagcagga catgacatgg tccggtgtga cggcgaggac agaggaggcg cgtccggcct   1380

tcctgaacac cttaggctgg tggggctgcg gcaagaagcg ggtctgtttc tttacttcct   1440

ccacggagtc ggcacactat ggctgccctc tgggctccca gaacccacaa catgaaaggt   1500

gaagctagag gaaccagacc tcatcagccc aacatcaaag acaccatcgg aacagcagcg   1560

cccgcagcac ccaccccgca ccggcgactc catcttcatg gccaccccct gcggcggacg   1620

gttgaccacc agccaccaca tcatcccaga gctgagctcc tccagcggga tgacgccgtc   1680

cccaccacct ccctcttctt ctttttcatc cttctgtctc tttgtttctg agctttcctg   1740

tctttccttt tttctgagag attcaaagcc tccacgactc tgtttccccc gtcccttctg   1800

aatttaattt gcactaagtc atttgcactg gttggagttg tggagacggc cttgagtctc   1860

agtacgagtg tgcgtgagtg tgagccacct tggcaagtgc ctgtgcaggg cccggccgcc   1920

ctccatctgg gccgggtgac tgggcgccgg ctgtgtgccc gaggcctcac cctgccctcg   1980

cctagtctgg aagctccgac cgacatcacg gagcagcctt caagcattcc attacgcccc   2040

atctcgctct gtgcccctcc ccaccagggc ttcagcagga gccctggact catcatcaat   2100

aaacactgtt acagcaatt                                                2119


<210>  7601
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7601

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7602
<211>  2323
<212>  DNA
<213>  Homo sapiens

<400>  7602
gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg gacatctgga     60

gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg tggggcctga    120

ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg acatcagctg    180

gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc atcccggtca    240

cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc agggtttgat    300

cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg accccatctg    360

ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct gaaagaagga    420

ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag aggggcagga    480

tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga ctgcgcaagg    540

ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag ggagcacagg    600

ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc agacagggac    660

atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc gcaattcatt    720

tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc ggagcctcga    780

gggctggaga gcgggaagac aggcagtgct cggggagttg cagcaggacg tcaccaggag    840

ggcgaagcgg ccacgggagg ggggccccgg gacattgcgc agcaaggagg ctgcaggggc    900

tcggcctgcg ggcgccggtc ccacgaggca ctgcggccca gggtctggtg cggagagggc    960

ccacagtgga cttggtgacg ctgtatgccc tcaccgctca gcccctgggg ctggcttggc   1020

agacagtaca gcatccaggg gagtcaaggg catggggcga gaccagacta ggcgaggcgg   1080

gcggggcgga gtgaatgagc tctcaggagg gaggatggtg caggcagggg tgaggagcgc   1140

agcgggcggc gagcgggagg cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg   1200

gcggcgacgg agccgggatc ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc   1260

agctggggtg gacgtgccca ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg   1320

acaagcagga catgacatgg tccggtgtga cggcgaggac agaggaggcg cgtccggcct   1380

tcctgaacac cttaggctgg tggggctgcg gcaagaagcg ggtctgtttc tttacttcct   1440

ccacggagtc ggcacactat ggctgccctc tgggctccca gaacccacaa catgaaagaa   1500

atggtgctac ccagctcaag cctgggcctt tgaatccgga cacaaaaccc tctagcttgg   1560

aaatgaatat gctgcacttt acaaccactg cactacctga ctcaggaatc ggctctggaa   1620

ggtgagcacc agcgctcctt ccggaagcct ccaggccccc gagcaccctg cccccatccc   1680

acccacgtgt cgctatctct aggtgaagct agaggaacca gacctcatca gcccaacatc   1740

aaagacacca tcggaacagc agcgcccgca gcacccaccc cgcaccggcg actccatctt   1800

catggccacc ccctgcggcg gacggttgac caccagccac cacatcatcc cagagctgag   1860

ctcctccagc gggatgacgc cgtccccacc acctccctct tcttcttttt catccttctg   1920

tctctttgtt tctgagcttt cctgtctttc cttttttctg agagattcaa agcctccacg   1980

actctgtttc ccccgtccct tctgaattta atttgcacta agtcatttgc actggttgga   2040

gttgtggaga cggccttgag tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa   2100

gtgcctgtgc agggcccggc cgccctccat ctgggccggg tgactgggcg ccggctgtgt   2160

gcccgaggcc tcaccctgcc ctcgcctagt ctggaagctc cgaccgacat cacggagcag   2220

ccttcaagca ttccattacg ccccatctcg ctctgtgccc ctccccacca gggcttcagc   2280

aggagccctg gactcatcat caataaacac tgttacagca att                     2323


<210>  7603
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7603

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7604
<211>  563
<212>  DNA
<213>  Homo sapiens

<400>  7604
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggaagttag caaaggtgac atcttctcgg ggggagccga gactgccttt    180

cctgtctttc cttttttctg agagattcaa agcctccacg actctgtttc ccccgtccct    240

tctgaattta atttgcacta agtcatttgc actggttgga gttgtggaga cggccttgag    300

tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc agggcccggc    360

cgccctccat ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc    420

ctcgcctagt ctggaagctc cgaccgacat cacggagcag ccttcaagca ttccattacg    480

ccccatctcg ctctgtgccc ctccccacca gggcttcagc aggagccctg gactcatcat    540

caataaacac tgttacagca att                                            563


<210>  7605
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7605

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Glu Val Ser Lys Gly Asp Ile Phe Ser Gly Gly 
            20                  25                  30


Ala Glu Thr Ala Phe Pro Val Phe Pro Phe Phe 
        35                  40


<210>  7606
<211>  1559
<212>  DNA
<213>  Homo sapiens

<400>  7606
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggattgcag caggacgtca ccaggagggc gaagcggcca cgggaggggg    180

gccccgggac attgcgcagc aaggaggctg caggggctcg gcctgcgggc gccggtccca    240

cgaggcactg cggcccaggg tctggtgcgg agagggccca cagtggactt ggtgacgctg    300

tatgccctca ccgctcagcc cctggggctg gcttggcaga cagtacagca tccaggggag    360

tcaagggcat ggggcgagac cagactaggc gaggcgggcg gggcggagtg aatgagctct    420

caggagggag gatggtgcag gcaggggtga ggagcgcagc gggcggcgag cgggaggcac    480

tggcctccag agcccgtggc caaggcgggc ctcgcgggcg gcgacggagc cgggatcggt    540

gcctcagcgt tcgggctgga gacgaggcca ggtctccagc tggggtggac gtgcccacca    600

gctgccgaag gccaagacgc caggtccggt ggacgtgaca agcaggacat gacatggtcc    660

ggtgtgacgg cgaggacaga ggaggcgcgt ccggccttcc tgaacacctt aggctggtgg    720

ggctgcggca agaagcgggt ctgtttcttt acttcctcca cggagtcggc acactatggc    780

tgccctctgg gctcccagaa cccacaacat gaaagaaatg gtgctaccca gctcaagcct    840

gggcctttga atccggacac aaaaccctct agcttggaaa tgaatatgct gcactttaca    900

accactgcac tacctgactc aggaatcggc tctggaaggt gaagctagag gaaccagacc    960

tcatcagccc aacatcaaag acaccatcgg aacagcagcg cccgcagcac ccaccccgca   1020

ccggcgactc catcttcatg gccaccccct gcggcggacg gttgaccacc agccaccaca   1080

tcatcccaga gctgagctcc tccagcggga tgacgccgtc cccaccacct ccctcttctt   1140

ctttttcatc cttctgtctc tttgtttctg agctttcctg tctttccttt tttctgagag   1200

attcaaagcc tccacgactc tgtttccccc gtcccttctg aatttaattt gcactaagtc   1260

atttgcactg gttggagttg tggagacggc cttgagtctc agtacgagtg tgcgtgagtg   1320

tgagccacct tggcaagtgc ctgtgcaggg cccggccgcc ctccatctgg gccgggtgac   1380

tgggcgccgg ctgtgtgccc gaggcctcac cctgccctcg cctagtctgg aagctccgac   1440

cgacatcacg gagcagcctt caagcattcc attacgcccc atctcgctct gtgcccctcc   1500

ccaccagggc ttcagcagga gccctggact catcatcaat aaacactgtt acagcaatt    1559


<210>  7607
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7607

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Asp Cys Ser Arg Thr Ser Pro Gly Gly Arg Ser 
            20                  25                  30


Gly His Gly Arg Gly Ala Pro Gly His Cys Ala Ala Arg Arg Leu Gln 
        35                  40                  45


Gly Leu Gly Leu Arg Ala Pro Val Pro Arg Gly Thr Ala Ala Gln Gly 
    50                  55                  60


Leu Val Arg Arg Gly Pro Thr Val Asp Leu Val Thr Leu Tyr Ala Leu 
65                  70                  75                  80


Thr Ala Gln Pro Leu Gly Leu Ala Trp Gln Thr Val Gln His Pro Gly 
                85                  90                  95


Glu Ser Arg Ala Trp Gly Glu Thr Arg Leu Gly Glu Ala Gly Gly Ala 
            100                 105                 110


Glu 



<210>  7608
<211>  1884
<212>  DNA
<213>  Homo sapiens

<400>  7608
ggggtgggat gggtgggggg taacggggga aactggggaa gtggggaacc gaggggcaac     60

caggggaaga tggggtgctg gaggagagct tgtgggagcc aaggagcacc ttggacatct    120

ggagtctggc aggaagttag caaaggtgac atcttctcgg ggggagccga gactgcgcaa    180

ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg agggagcaca    240

ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg tcagacaggg    300

acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca ccgcaattca    360

tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg ccggagcctc    420

gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga cgtcaccagg    480

agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga ggctgcaggg    540

gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg tgcggagagg    600

gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg ggctggcttg    660

gcagacagta cagcatccag gggagtcaag ggcatggggc gagaccagac taggcgaggc    720

gggcggggcg gagtgaatga gctctcagga gggaggatgg tgcaggcagg ggtgaggagc    780

gcagcgggcg gcgagcggga ggcactggcc tccagagccc gtggccaagg cgggcctcgc    840

gggcggcgac ggagccggga tcggtgcctc agcgttcggg ctggagacga ggccaggtct    900

ccagctgggg tggacgtgcc caccagctgc cgaaggccaa gacgccaggt ccggtggacg    960

tgacaagcag gacatgacat ggtccggtgt gacggcgagg acagaggagg cgcgtccggc   1020

cttcctgaac accttaggct ggtggggctg cggcaagaag cgggtctgtt tctttacttc   1080

ctccacggag tcggcacact atggctgccc tctgggctcc cagaacccac aacatgaaag   1140

aaatggtgct acccagctca agcctgggcc tttgaatccg gacacaaaac cctctagctt   1200

ggaaatgaat atgctgcact ttacaaccac tgcactacct gactcaggaa tcggctctgg   1260

aaggtgaagc tagaggaacc agacctcatc agcccaacat caaagacacc atcggaacag   1320

cagcgcccgc agcacccacc ccgcaccggc gactccatct tcatggccac cccctgcggc   1380

ggacggttga ccaccagcca ccacatcatc ccagagctga gctcctccag cgggatgacg   1440

ccgtccccac cacctccctc ttcttctttt tcatccttct gtctctttgt ttctgagctt   1500

tcctgtcttt ccttttttct gagagattca aagcctccac gactctgttt cccccgtccc   1560

ttctgaattt aatttgcact aagtcatttg cactggttgg agttgtggag acggccttga   1620

gtctcagtac gagtgtgcgt gagtgtgagc caccttggca agtgcctgtg cagggcccgg   1680

ccgccctcca tctgggccgg gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc   1740

cctcgcctag tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac   1800

gccccatctc gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca   1860

tcaataaaca ctgttacagc aatt                                          1884


<210>  7609
<211>  297
<212>  PRT
<213>  Homo sapiens

<400>  7609

Met Gly Cys Trp Arg Arg Ala Cys Gly Ser Gln Gly Ala Pro Trp Thr 
1               5                   10                  15


Ser Gly Val Trp Gln Glu Val Ser Lys Gly Asp Ile Phe Ser Gly Gly 
            20                  25                  30


Ala Glu Thr Ala Gln Gly Trp Gly Val Met Gly Pro Phe Gln Ala Glu 
        35                  40                  45


Arg Ala Arg Gly Gln Gly Gly Ser Thr Gly Val Ala Ser Val Gly Ser 
    50                  55                  60


Ser Thr Trp Gly Gly Thr Pro Gly Leu Gly Gln Thr Gly Thr Trp Gln 
65                  70                  75                  80


Gly Thr Gln Asp Arg Gly Val Pro Ser Cys His Leu Thr His Arg Asn 
                85                  90                  95


Ser Phe Ser Ser Arg His Arg Gly Ser Ser Gly Thr Ala Phe Ser Gly 
            100                 105                 110


Leu Cys Arg Ser Leu Glu Gly Trp Arg Ala Gly Arg Gln Ala Val Leu 
        115                 120                 125


Gly Glu Leu Gln Gln Asp Val Thr Arg Arg Ala Lys Arg Pro Arg Glu 
    130                 135                 140


Gly Gly Pro Gly Thr Leu Arg Ser Lys Glu Ala Ala Gly Ala Arg Pro 
145                 150                 155                 160


Ala Gly Ala Gly Pro Thr Arg His Cys Gly Pro Gly Ser Gly Ala Glu 
                165                 170                 175


Arg Ala His Ser Gly Leu Gly Asp Ala Val Cys Pro His Arg Ser Ala 
            180                 185                 190


Pro Gly Ala Gly Leu Ala Asp Ser Thr Ala Ser Arg Gly Val Lys Gly 
        195                 200                 205


Met Gly Arg Asp Gln Thr Arg Arg Gly Gly Arg Gly Gly Val Asn Glu 
    210                 215                 220


Leu Ser Gly Gly Arg Met Val Gln Ala Gly Val Arg Ser Ala Ala Gly 
225                 230                 235                 240


Gly Glu Arg Glu Ala Leu Ala Ser Arg Ala Arg Gly Gln Gly Gly Pro 
                245                 250                 255


Arg Gly Arg Arg Arg Ser Arg Asp Arg Cys Leu Ser Val Arg Ala Gly 
            260                 265                 270


Asp Glu Ala Arg Ser Pro Ala Gly Val Asp Val Pro Thr Ser Cys Arg 
        275                 280                 285


Arg Pro Arg Arg Gln Val Arg Trp Thr 
    290                 295


<210>  7610
<211>  2091
<212>  DNA
<213>  Homo sapiens

<400>  7610
gagggagggg gtgggatggg tggggggtaa cgggggaaac tggggaagtg gggaaccgag     60

gggcaaccag gggaagatgg ggtgctggag gagagcttgt gggagccaag gagcaccttg    120

gacatctgga gtctggcagg agtgatgacg ggtggagggg ctagctcgag gcagggctgg    180

tggggcctga ggccagtgag gagtgtggag taggcgccca ggcatcgtgc agacagggcg    240

acatcagctg gggacgatgg gcctgagcta gggctggaaa gaagggggag ccaggcattc    300

atcccggtca cttttggtta caggacgtgg cagctggttg gacgagggga gctggtgggc    360

agggtttgat cccagggcct gggcaacgga ggtgtagctg gcagcagcgg gcaggtgagg    420

accccatctg ccgggcaggt gagtcccttc cctccccagg cctcgcttcc ccagccttct    480

gaaagaagga ggtttagggg atcgagggct ggcggggaga agcagacacc ctcccagcag    540

aggggcagga tgggggcagg agagttagca aaggtgacat cttctcgggg ggagccgaga    600

ctgcgcaagg ctggggggtt atgggcccgt tccaggcaga aagagcaaga gggcagggag    660

ggagcacagg ggtggccagc gtagggtcca gcacgtgggg tggtacccca ggcctgggtc    720

agacagggac atggcagggg acacaggaca gaggggtccc cagctgccac ctcacccacc    780

gcaattcatt tagtagcagg cacaggggca gctccggcac ggctttctca ggcctatgcc    840

ggagcctcga gggctggaga gcgggaagac aggcatacag catccagggg agtcaagggc    900

atggggcgag accagactag gcgaggcggg cggggcggag tgaatgagct ctcaggaggg    960

aggatggtgc aggcaggggt gaggagcgca gcgggcggcg agcgggaggc actggcctcc   1020

agagcccgtg gccaaggcgg gcctcgcggg cggcgacgga gccgggatcg gtgcctcagc   1080

gttcgggctg gagacgaggc caggtctcca gctggggtgg acgtgcccac cagctgccga   1140

aggccaagac gccaggtccg gtggacgtga caagcaggac atgacatggt ccggtgtgac   1200

ggcgaggaca gaggaggcgc gtccggcctt cctgaacacc ttaggctggt ggggctgcgg   1260

caagaagcgg gtctgtttct ttacttcctc cacggagtcg gcacactatg gctgccctct   1320

gggctcccag aacccacaac atgaaagaaa tggtgctacc cagctcaagc ctgggccttt   1380

gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta caaccactgc   1440

actacctgac tcaggaatcg gctctggaag gtgaagctag aggaaccaga cctcatcagc   1500

ccaacatcaa agacaccatc ggaacagcag cgcccgcagc acccaccccg caccggcgac   1560

tccatcttca tggccacccc ctgcggcgga cggttgacca ccagccacca catcatccca   1620

gagctgagct cctccagcgg gatgacgccg tccccaccac ctccctcttc ttctttttca   1680

tccttctgtc tctttgtttc tgagctttcc tgtctttcct tttttctgag agattcaaag   1740

cctccacgac tctgtttccc ccgtcccttc tgaatttaat ttgcactaag tcatttgcac   1800

tggttggagt tgtggagacg gccttgagtc tcagtacgag tgtgcgtgag tgtgagccac   1860

cttggcaagt gcctgtgcag ggcccggccg ccctccatct gggccgggtg actgggcgcc   1920

ggctgtgtgc ccgaggcctc accctgccct cgcctagtct ggaagctccg accgacatca   1980

cggagcagcc ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct ccccaccagg   2040

gcttcagcag gagccctgga ctcatcatca ataaacactg ttacagcaat t            2091


<210>  7611
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  7611

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Tyr Ser Ile Gln Gly Ser Gln Gly His Gly Ala 
                85                  90                  95


Arg Pro Asp 



<210>  7612
<211>  1981
<212>  DNA
<213>  Homo sapiens

<400>  7612
gtgagggagg gggtgggatg ggtggggggt aacgggggaa actggggaag tggggaaccg     60

aggggcaacc aggggaagat ggggtgctgg aggagagctt gtgggagcca aggagcacct    120

tggacatctg gagtctggca ggagtgatga cgggtggagg ggctagctcg aggcagggct    180

ggtggggcct gaggccagtg aggagtgtgg agtaggcgcc caggcatcgt gcagacaggg    240

cgacatcagc tggggacgat gggcctgagc tagggctgga aagaaggggg agccaggcat    300

tcatcccggt cacttttggt tacaggacgt ggcagctggt tggacgaggg gagctggtgg    360

gcagggtttg atcccagggc ctgggcaacg gaggtgtagc tggcagcagc gggcaggtga    420

ggaccccatc tgccgggcag gtgagtccct tccctcccca ggcctcgctt ccccagcctt    480

ctgaaagaag gaggtttagg ggatcgaggg ctggcgggga gaagcagaca ccctcccagc    540

agaggggcag gatgggggca ggagagttag caaaggtgac atcttctcgg ggggagccga    600

gactgcgcaa ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg    660

agggagcaca ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg    720

tcagacaggg acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca    780

ccgcaattca tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg    840

ccggagcctc gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga    900

cgtcaccagg agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga    960

ggctgcaggg gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg   1020

tgcggagagg gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg   1080

ggctggcttg gcagacagta cagtccggtg gacgtgacaa gcagaacacc ttaggctggt   1140

ggggctgcgg caagaagcgg gtctgtttct ttacttcctc cacggagtcg gcacactatg   1200

gctgccctct gggctcccag aacccacaac atgaaagaaa tggtgctacc cagctcaagc   1260

ctgggccttt gaatccggac acaaaaccct ctagcttgga aatgaatatg ctgcacttta   1320

caaccactgc actacctgac tcaggaatcg gctctggaag gtgaagctag aggaaccaga   1380

cctcatcagc ccaacatcaa agacaccatc ggaacagcag cgcccgcagc acccaccccg   1440

caccggcgac tccatcttca tggccacccc ctgcggcgga cggttgacca ccagccacca   1500

catcatccca gagctgagct cctccagcgg gatgacgccg tccccaccac ctccctcttc   1560

ttctttttca tccttctgtc tctttgtttc tgagctttcc tgtctttcct tttttctgag   1620

agattcaaag cctccacgac tctgtttccc ccgtcccttc tgaatttaat ttgcactaag   1680

tcatttgcac tggttggagt tgtggagacg gccttgagtc tcagtacgag tgtgcgtgag   1740

tgtgagccac cttggcaagt gcctgtgcag ggcccggccg ccctccatct gggccgggtg   1800

actgggcgcc ggctgtgtgc ccgaggcctc accctgccct cgcctagtct ggaagctccg   1860

accgacatca cggagcagcc ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct   1920

ccccaccagg gcttcagcag gagccctgga ctcatcatca ataaacactg ttacagcaat   1980

t                                                                   1981


<210>  7613
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  7613

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Val Arg Trp Thr 



<210>  7614
<211>  958
<212>  DNA
<213>  Homo sapiens

<400>  7614
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggaaaatgg tgctacccag ctcaagcctg    240

ggcctttgaa tccggacaca aaaccctcta gcttggaaat gaatatgctg cactttacaa    300

ccactgcact acctgactca ggaatcggct ctggaaggtg aagctagagg aaccagacct    360

catcagccca acatcaaaga caccatcgga acagcagcgc ccgcagcacc caccccgcac    420

cggcgactcc atcttcatgg ccaccccctg cggcggacgg ttgaccacca gccaccacat    480

catcccagag ctgagctcct ccagcgggat gacgccgtcc ccaccacctc cctcttcttc    540

tttttcatcc ttctgtctct ttgtttctga gctttcctgt ctttcctttt ttctgagaga    600

ttcaaagcct ccacgactct gtttcccccg tcccttctga atttaatttg cactaagtca    660

tttgcactgg ttggagttgt ggagacggcc ttgagtctca gtacgagtgt gcgtgagtgt    720

gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc tccatctggg ccgggtgact    780

gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc ctagtctgga agctccgacc    840

gacatcacgg agcagccttc aagcattcca ttacgcccca tctcgctctg tgcccctccc    900

caccagggct tcagcaggag ccctggactc atcatcaata aacactgtta cagcaatt      958


<210>  7615
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  7615

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Gly Trp Trp Gly Leu Arg 
1               5                   10                  15


Pro Val Arg Ser Val Glu Asn Gly Ala Thr Gln Leu Lys Pro Gly Pro 
            20                  25                  30


Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met Leu His 
        35                  40                  45


Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly Arg 
    50                  55                  60


<210>  7616
<211>  2096
<212>  DNA
<213>  Homo sapiens

<400>  7616
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggaggtt tgatcccagg gcctgggcaa cggaggtgta    180

gctggcagca gcgggcaggt gaggacccca tctgccgggc aggtgagtcc cttccctccc    240

caggcctcgc ttccccagcc ttctgaaaga aggaggttta ggggatcgag ggctggcggg    300

gagaagcaga caccctccca gcagaggggc aggatggggg caggagagtt agcaaaggtg    360

acatcttctc ggggggagcc gagactgcgc aaggctgggg ggttatgggc ccgttccagg    420

cagaaagagc aagagggcag ggagggagca caggggtggc cagcgtaggg tccagcacgt    480

ggggtggtac cccaggcctg ggtcagacag ggacatggca ggggacacag gacagagggg    540

tccccagctg ccacctcacc caccgcaatt catttagtag caggcacagg ggcagctccg    600

gcacggcttt ctcaggccta tgccggagcc tcgagggctg gagagcggga agacaggcag    660

tgctcgggga gttgcagcag gacgtcacca ggagggcgaa gcggccacgg gaggggggcc    720

ccgggacatt gcgcagcaag gaggctgcag gggctcggcc tgcgggcgcc ggtcccacga    780

ggcactgcgg cccagggtct ggtgcggaga gggcccacag tggacttggt gacgctgtat    840

gccctcaccg ctcagcccct ggggctggct tggcagacag tacagcatcc aggggagtca    900

agggcatggg gcgagaccag actaggcgag gcgggcgggg cggagtgaat gagctctcag    960

gagggaggat ggtgcaggca ggggtgagga gcgcagcggg cggcgagcgg gaggcactgg   1020

cctccagagc ccgtggccaa ggcgggcctc gcgggcggcg acggagccgg gatcggtgcc   1080

tcagcgttcg ggctggagac gaggccaggt ctccagctgg ggtggacgtg cccaccagct   1140

gccgaaggcc aagacgccag gtccggtgga cgtgacaagc aggacatgac atggtccggt   1200

gtgacggcga ggacagagga ggcgcgtccg gccttcctga acaccttagg ctggtggggc   1260

tgcggcaaga agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc   1320

cctctgggct cccagaaccc acaacatgaa agaaatggtg ctacccagct caagcctggg   1380

cctttgaatc cggacacaaa accctctagc ttggaaatga atatgctgca ctttacaacc   1440

actgcactac ctgactcagg aatcggctct ggaaggtgaa gctagaggaa ccagacctca   1500

tcagcccaac atcaaagaca ccatcggaac agcagcgccc gcagcaccca ccccgcaccg   1560

gcgactccat cttcatggcc accccctgcg gcggacggtt gaccaccagc caccacatca   1620

tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt   1680

tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt   1740

caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt   1800

tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga   1860

gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg   1920

gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga   1980

catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca   2040

ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca gcaatt       2096


<210>  7617
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7617

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7618
<211>  1605
<212>  DNA
<213>  Homo sapiens

<400>  7618
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgtcacc aggagggcga agcggccacg ggaggggggc cccgggacat tgcgcagcaa    960

ggaggctgca ggggctcggc ctgcgggcgc cggtcccacg aggcactgcg gcccagggtc   1020

tggtgcggag agggcccaca gtggacttgg tgacgctgta tgccctcacc gctcagcccc   1080

tggggctggc ttggcagaca gtacagcatc caggggagtc aagggcatgg ggcgagacca   1140

gactaggcga ggcgggcggg gcggagtgaa tgagctccct cttcttcttt ttcatccttc   1200

tgtctctttg tttctgagct ttcctgtctt tccttttttc tgagagattc aaagcctcca   1260

cgactctgtt tcccccgtcc cttctgaatt taatttgcac taagtcattt gcactggttg   1320

gagttgtgga gacggccttg agtctcagta cgagtgtgcg tgagtgtgag ccaccttggc   1380

aagtgcctgt gcagggcccg gccgccctcc atctgggccg ggtgactggg cgccggctgt   1440

gtgcccgagg cctcaccctg ccctcgccta gtctggaagc tccgaccgac atcacggagc   1500

agccttcaag cattccatta cgccccatct cgctctgtgc ccctccccac cagggcttca   1560

gcaggagccc tggactcatc atcaataaac actgttacag caatt                   1605


<210>  7619
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  7619

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Pro Leu Leu Leu Phe His Pro Ser 
            180                 185                 190


Val Ser Leu Phe Leu Ser Phe Pro Val Phe Pro Phe Phe 
        195                 200                 205


<210>  7620
<211>  1186
<212>  DNA
<213>  Homo sapiens

<400>  7620
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagacgtg cccaccagct gccgaaggcc    240

aagacgccag gtccggtgga cgtgacaagc aggacatgac atggtccggt gtgacggcga    300

ggacagagga ggcgcgtccg gccttcctga acaccttagg ctggtggggc tgcggcaaga    360

agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc cctctgggct    420

cccagaaccc acaacatgaa agaaatggtg ctacccagct caagcctggg cctttgaatc    480

cggacacaaa accctctagc ttggaaatga atatgctgca ctttacaacc actgcactac    540

ctgactcagg aatcggctct ggaaggtgaa gctagaggaa ccagacctca tcagcccaac    600

atcaaagaca ccatcggaac agcagcgccc gcagcaccca ccccgcaccg gcgactccat    660

cttcatggcc accccctgcg gcggacggtt gaccaccagc caccacatca tcccagagct    720

gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt tttcatcctt    780

ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt caaagcctcc    840

acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt tgcactggtt    900

ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga gccaccttgg    960

caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg gcgccggctg   1020

tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga catcacggag   1080

cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca ccagggcttc   1140

agcaggagcc ctggactcat catcaataaa cactgttaca gcaatt                  1186


<210>  7621
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  7621

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Gly Trp Trp Gly Leu Arg 
1               5                   10                  15


Pro Val Arg Ser Val Glu Thr Cys Pro Pro Ala Ala Glu Gly Gln Asp 
            20                  25                  30


Ala Arg Ser Gly Gly Arg Asp Lys Gln Asp Met Thr Trp Ser Gly Val 
        35                  40                  45


Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala Phe Leu Asn Thr Leu Gly 
    50                  55                  60


Trp Trp Gly Cys Gly Lys Lys Arg Val Cys Phe Phe Thr Ser Ser Thr 
65                  70                  75                  80


Glu Ser Ala His Tyr Gly Cys Pro Leu Gly Ser Gln Asn Pro Gln His 
                85                  90                  95


Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro Gly Pro Leu Asn Pro Asp 
            100                 105                 110


Thr Lys Pro Ser Ser Leu Glu Met Asn Met Leu His Phe Thr Thr Thr 
        115                 120                 125


Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly Arg 
    130                 135


<210>  7622
<211>  1878
<212>  DNA
<213>  Homo sapiens

<400>  7622
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgtcacc aggagggcga agcggccacg ggaggggggc cccgggacat tgcgcagcaa    960

ggaggctgca ggggctcggc ctgcgggcgc cggtcccacg aggcactgcg gcccagggtc   1020

tggtgcggag agggcccaca gtggacttgg tgacgctgta tgccctcacc gctcagcccc   1080

tggggctggc ttggcagaca gtacagcatc caggggaaac ccacaacatg aaagaaatgg   1140

tgctacccag ctcaagcctg ggcctttgaa tccggacaca aaaccctcta gcttggaaat   1200

gaatatgctg cactttacaa ccactgcact acctgactca ggaatcggct ctggaaggtg   1260

aagctagagg aaccagacct catcagccca acatcaaaga caccatcgga acagcagcgc   1320

ccgcagcacc caccccgcac cggcgactcc atcttcatgg ccaccccctg cggcggacgg   1380

ttgaccacca gccaccacat catcccagag ctgagctcct ccagcgggat gacgccgtcc   1440

ccaccacctc cctcttcttc tttttcatcc ttctgtctct ttgtttctga gctttcctgt   1500

ctttcctttt ttctgagaga ttcaaagcct ccacgactct gtttcccccg tcccttctga   1560

atttaatttg cactaagtca tttgcactgg ttggagttgt ggagacggcc ttgagtctca   1620

gtacgagtgt gcgtgagtgt gagccacctt ggcaagtgcc tgtgcagggc ccggccgccc   1680

tccatctggg ccgggtgact gggcgccggc tgtgtgcccg aggcctcacc ctgccctcgc   1740

ctagtctgga agctccgacc gacatcacgg agcagccttc aagcattcca ttacgcccca   1800

tctcgctctg tgcccctccc caccagggct tcagcaggag ccctggactc atcatcaata   1860

aacactgtta cagcaatt                                                 1878


<210>  7623
<211>  211
<212>  PRT
<213>  Homo sapiens

<400>  7623

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu 
                165                 170                 175


Lys Pro Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met 
            180                 185                 190


Asn Met Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly 
        195                 200                 205


Ser Gly Arg 
    210


<210>  7624
<211>  846
<212>  DNA
<213>  Homo sapiens

<400>  7624
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagagaca ccatcggaac agcagcgccc gcagcaccca    300

ccccgcaccg gcgactccat cttcatggcc accccctgcg gcggacggtt gaccaccagc    360

caccacatca tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc    420

tcttcttctt tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt    480

ctgagagatt caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca    540

ctaagtcatt tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc    600

gtgagtgtga gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc    660

gggtgactgg gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag    720

ctccgaccga catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg    780

cccctcccca ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca    840

gcaatt                                                               846


<210>  7625
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7625

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7626
<211>  993
<212>  DNA
<213>  Homo sapiens

<400>  7626
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcatt tacaaccact gcactacctg actcaggaat    360

cggctctgga aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca    420

tcggaacagc agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc    480

ccctgcggcg gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc    540

gggatgacgc cgtccccacc acctccctct tcttcttttt catccttctg tctctttgtt    600

tctgagcttt cctgtctttc cttttttctg agagattcaa agcctccacg actctgtttc    660

ccccgtccct tctgaattta atttgcacta agtcatttgc actggttgga gttgtggaga    720

cggccttgag tctcagtacg agtgtgcgtg agtgtgagcc accttggcaa gtgcctgtgc    780

agggcccggc cgccctccat ctgggccggg tgactgggcg ccggctgtgt gcccgaggcc    840

tcaccctgcc ctcgcctagt ctggaagctc cgaccgacat cacggagcag ccttcaagca    900

ttccattacg ccccatctcg ctctgtgccc ctccccacca gggcttcagc aggagccctg    960

gactcatcat caataaacac tgttacagca att                                 993


<210>  7627
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7627

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7628
<211>  1682
<212>  DNA
<213>  Homo sapiens

<400>  7628
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcact tttggttaca ggacgtggca gctggttgga    360

cgaggggagc tggtgggcag gggtctggtg cggagagggc ccacagtgga cttggtgacg    420

ctgtatgccc tcaccgctca gcccctgggg ctggcttggc agacagtaca gcatccaggg    480

gagtcaaggg catggggcga gaccagacta ggcgaggcgg gcggggcgga gtgaatgagc    540

tctcaggagg gaggatggtg caggcagggg tgaggagcgc agcgggcggc gagcgggagg    600

cactggcctc cagagcccgt ggccaaggcg ggcctcgcgg gcggcgacgg agccgggatc    660

ggtgcctcag cgttcgggct ggagacgagg ccaggtctcc agctggggtg gacgtgccca    720

ccagctgccg aaggccaaga cgccaggtcc ggtggacgtg acaagcagga catgacatgg    780

tccggtgtga cggcgaggac agaggaggcg cgtccggcct tcctgaacac cttaggctgg    840

tggggctgcg gcaagaagcg ggtctgtttc tttacttcct ccacggagtc ggcacactat    900

ggctgccctc tgggctccca gaacccacaa catgaaagaa atggtgctac ccagctcaag    960

cctgggcctt tgaatccgga cacaaaaccc tctagcttgg aaatgaatat gctgcacttt   1020

acaaccactg cactacctga ctcaggaatc ggctctggaa ggtgaagcta gaggaaccag   1080

acctcatcag cccaacatca aagacaccat cggaacagca gcgcccgcag cacccacccc   1140

gcaccggcga ctccatcttc atggccaccc cctgcggcgg acggttgacc accagccacc   1200

acatcatccc agagctgagc tcctccagcg ggatgacgcc gtccccacca cctccctctt   1260

cttctttttc atccttctgt ctctttgttt ctgagctttc ctgtctttcc ttttttctga   1320

gagattcaaa gcctccacga ctctgtttcc cccgtccctt ctgaatttaa tttgcactaa   1380

gtcatttgca ctggttggag ttgtggagac ggccttgagt ctcagtacga gtgtgcgtga   1440

gtgtgagcca ccttggcaag tgcctgtgca gggcccggcc gccctccatc tgggccgggt   1500

gactgggcgc cggctgtgtg cccgaggcct caccctgccc tcgcctagtc tggaagctcc   1560

gaccgacatc acggagcagc cttcaagcat tccattacgc cccatctcgc tctgtgcccc   1620

tccccaccag ggcttcagca ggagccctgg actcatcatc aataaacact gttacagcaa   1680

tt                                                                  1682


<210>  7629
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7629

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7630
<211>  1814
<212>  DNA
<213>  Homo sapiens

<400>  7630
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctgcc acctcaccca ccgcaattca tttagtagca    300

ggcacagggg cagctccggc acggctttct caggcctatg ccggagcctc gagggctgga    360

gagcgggaag acaggcagtg ctcggggagt tgcagcagga cgtcaccagg agggcgaagc    420

ggccacggga ggggggcccc gggacattgc gcagcaagga ggctgcaggg gctcggcctg    480

cgggcgccgg tcccacgagg cactgcggcc cagggtctgg tgcggagagg gcccacagtg    540

gacttggtga cgctgtatgc cctcaccgct cagcccctgg ggctggcttg gcagacagta    600

cagcatccag gggagtcaag ggcatggggc gagaccagac taggcgaggc gggcggggcg    660

gagtgaatga gctctcagga gggaggatgg tgcaggcagg ggtgaggagc gcagcgggcg    720

gcgagcggga ggcactggcc tccagagccc gtggccaagg cgggcctcgc gggcggcgac    780

ggagccggga tcggtgcctc agcgttcggg ctggagacga ggccaggtct ccagctgggg    840

tggacgtgcc caccagctgc cgaaggccaa gacgccaggt ccggtggacg tgacaagcag    900

gacatgacat ggtccggtgt gacggcgagg acagaggagg cgcgtccggc cttcctgaac    960

accttaggct ggtggggctg cggcaagaag cgggtctgtt tctttacttc ctccacggag   1020

tcggcacact atggctgccc tctgggctcc cagaacccac aacatgaaag aaatggtgct   1080

acccagctca agcctgggcc tttgaatccg gacacaaaac cctctagctt ggaaatgaat   1140

atgctgcact ttacaaccac tgcactacct gactcaggaa tcggctctgg aaggtgaagc   1200

tagaggaacc agacctcatc agcccaacat caaagacacc atcggaacag cagcgcccgc   1260

agcacccacc ccgcaccggc gactccatct tcatggccac cccctgcggc ggacggttga   1320

ccaccagcca ccacatcatc ccagagctga gctcctccag cgggatgacg ccgtccccac   1380

cacctccctc ttcttctttt tcatccttct gtctctttgt ttctgagctt tcctgtcttt   1440

ccttttttct gagagattca aagcctccac gactctgttt cccccgtccc ttctgaattt   1500

aatttgcact aagtcatttg cactggttgg agttgtggag acggccttga gtctcagtac   1560

gagtgtgcgt gagtgtgagc caccttggca agtgcctgtg cagggcccgg ccgccctcca   1620

tctgggccgg gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc cctcgcctag   1680

tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac gccccatctc   1740

gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca tcaataaaca   1800

ctgttacagc aatt                                                     1814


<210>  7631
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  7631

Met Thr Trp Ser Gly Val Thr Ala Arg Thr Glu Glu Ala Arg Pro Ala 
1               5                   10                  15


Phe Leu Asn Thr Leu Gly Trp Trp Gly Cys Gly Lys Lys Arg Val Cys 
            20                  25                  30


Phe Phe Thr Ser Ser Thr Glu Ser Ala His Tyr Gly Cys Pro Leu Gly 
        35                  40                  45


Ser Gln Asn Pro Gln His Glu Arg Asn Gly Ala Thr Gln Leu Lys Pro 
    50                  55                  60


Gly Pro Leu Asn Pro Asp Thr Lys Pro Ser Ser Leu Glu Met Asn Met 
65                  70                  75                  80


Leu His Phe Thr Thr Thr Ala Leu Pro Asp Ser Gly Ile Gly Ser Gly 
                85                  90                  95


Arg 



<210>  7632
<211>  2350
<212>  DNA
<213>  Homo sapiens

<400>  7632
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat    660

gggcccgttc caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt    720

agggtccagc acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac    780

acaggacaga ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca    840

caggggcagc tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc    900

gggaagacag gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc    960

acgggagggg ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg   1020

cgccggtccc acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact   1080

tggtgacgct gtatgccctc accgctcagc ccctggggct ggcttggcag acagtacagc   1140

atccagggga gtcaagggca tggggcgaga ccagactagg cgaggcgggc ggggcggagt   1200

gaatgagctc tcaggaggga ggatggtgca ggcaggggtg aggagcgcag cgggcggcga   1260

gcgggaggca ctggcctcca gagcccgtgg ccaaggcggg cctcgcgggc ggcgacggag   1320

ccgggatcgg tgcctcagcg ttcgggctgg agacgaggcc aggtctccag ctggggtgga   1380

cgtgcccacc agctgccgaa ggccaagacg ccaggtccgg tggacgtgac aagcaggaca   1440

tgacatggtc cggtgtgacg gcgaggacag aggaggcgcg tccggccttc ctgaacacct   1500

taggctggtg gggctgcggc aagaagcggg tctgtttctt tacttcctcc acggagtcgg   1560

cacactatgg ctgccctctg ggctcccaga acccacaaca tgaaagaaat ggtgctaccc   1620

agctcaagcc tgggcctttg aatccggaca caaaaccctc tagcttggaa atgaatatgc   1680

tgcactttac aaccactgca ctacctgact caggaatcgg ctctggaagg tgaagctaga   1740

ggaaccagac ctcatcagcc caacatcaaa gacaccatcg gaacagcagc gcccgcagca   1800

cccaccccgc accggcgact ccatcttcat ggccaccccc tgcggcggac ggttgaccac   1860

cagccaccac atcatcccag agctgagctc ctccagcggg atgacgccgt ccccaccacc   1920

tccctcttct tctttttcat ccttctgtct ctttgtttct gagctttcct gtctttcctt   1980

ttttctgaga gattcaaagc ctccacgact ctgtttcccc cgtcccttct gaatttaatt   2040

tgcactaagt catttgcact ggttggagtt gtggagacgg ccttgagtct cagtacgagt   2100

gtgcgtgagt gtgagccacc ttggcaagtg cctgtgcagg gcccggccgc cctccatctg   2160

ggccgggtga ctgggcgccg gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg   2220

gaagctccga ccgacatcac ggagcagcct tcaagcattc cattacgccc catctcgctc   2280

tgtgcccctc cccaccaggg cttcagcagg agccctggac tcatcatcaa taaacactgt   2340

tacagcaatt                                                          2350


<210>  7633
<211>  256
<212>  PRT
<213>  Homo sapiens

<400>  7633

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp Glu Ala Arg Ser Pro Ala Gly Val 
225                 230                 235                 240


Asp Val Pro Thr Ser Cys Arg Arg Pro Arg Arg Gln Val Arg Trp Thr 
                245                 250                 255


<210>  7634
<211>  1910
<212>  DNA
<213>  Homo sapiens

<400>  7634
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat    660

gggcccgttc caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt    720

agggtccagc acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac    780

acaggacaga ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca    840

caggggcagc tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc    900

gggaagacag gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc    960

acgggagggg ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg   1020

cgccggtccc acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact   1080

tggtgacgct gtatgccctc accgctcagc ccctggggct ggcttggcag acactgagtg   1140

ggacctcact ccttccccat ccacagaaat ggtgctaccc agctcaagcc tgggcctttg   1200

aatccggaca caaaaccctc tagcttggaa atgaatatgc tgcactttac aaccactgca   1260

ctacctgact caggaatcgg ctctggaagg tgaagctaga ggaaccagac ctcatcagcc   1320

caacatcaaa gacaccatcg gaacagcagc gcccgcagca cccaccccgc accggcgact   1380

ccatcttcat ggccaccccc tgcggcggac ggttgaccac cagccaccac atcatcccag   1440

agctgagctc ctccagcggg atgacgccgt ccccaccacc tccctcttct tctttttcat   1500

ccttctgtct ctttgtttct gagctttcct gtctttcctt ttttctgaga gattcaaagc   1560

ctccacgact ctgtttcccc cgtcccttct gaatttaatt tgcactaagt catttgcact   1620

ggttggagtt gtggagacgg ccttgagtct cagtacgagt gtgcgtgagt gtgagccacc   1680

ttggcaagtg cctgtgcagg gcccggccgc cctccatctg ggccgggtga ctgggcgccg   1740

gctgtgtgcc cgaggcctca ccctgccctc gcctagtctg gaagctccga ccgacatcac   1800

ggagcagcct tcaagcattc cattacgccc catctcgctc tgtgcccctc cccaccaggg   1860

cttcagcagg agccctggac tcatcatcaa taaacactgt tacagcaatt              1910


<210>  7635
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7635

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Thr Glu 
145                 150                 155                 160


Trp Asp Leu Thr Pro Ser Pro Ser Thr Glu Met Val Leu Pro Ser Ser 
                165                 170                 175


Ser Leu Gly Leu 
            180


<210>  7636
<211>  1248
<212>  DNA
<213>  Homo sapiens

<400>  7636
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcggggtg aagctagagg aaccagacct catcagccca    660

acatcaaaga caccatcgga acagcagcgc ccgcagcacc caccccgcac cggcgactcc    720

atcttcatgg ccaccccctg cggcggacgg ttgaccacca gccaccacat catcccagag    780

ctgagctcct ccagcgggat gacgccgtcc ccaccacctc cctcttcttc tttttcatcc    840

ttctgtctct ttgtttctga gctttcctgt ctttcctttt ttctgagaga ttcaaagcct    900

ccacgactct gtttcccccg tcccttctga atttaatttg cactaagtca tttgcactgg    960

ttggagttgt ggagacggcc ttgagtctca gtacgagtgt gcgtgagtgt gagccacctt   1020

ggcaagtgcc tgtgcagggc ccggccgccc tccatctggg ccgggtgact gggcgccggc   1080

tgtgtgcccg aggcctcacc ctgccctcgc ctagtctgga agctccgacc gacatcacgg   1140

agcagccttc aagcattcca ttacgcccca tctcgctctg tgcccctccc caccagggct   1200

tcagcaggag ccctggactc atcatcaata aacactgtta cagcaatt                1248


<210>  7637
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7637

Met Gly Ala Gly Glu Leu Ala Lys Val Thr Ser Ser Arg Gly Glu Ala 
1               5                   10                  15


Arg Gly Thr Arg Pro His Gln Pro Asn Ile Lys Asp Thr Ile Gly Thr 
            20                  25                  30


Ala Ala Pro Ala Ala Pro Thr Pro His Arg Arg Leu His Leu His Gly 
        35                  40                  45


His Pro Leu Arg Arg Thr Val Asp His Gln Pro Pro His His Pro Arg 
    50                  55                  60


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
65                  70                  75                  80


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
                85                  90


<210>  7638
<211>  1563
<212>  DNA
<213>  Homo sapiens

<400>  7638
gctaatttag gagcttgaga tgctaaagag ctgggagtgc cactgctgct ttattctggg     60

gtctaggatc cttgtgttgg ctgagataat ctgctaatgt gggtgcagca gacatcccgc    120

ggtttgtgga atcgataaag gatggggatc aatggtgttt gtgcactgtg cggtctgtgc    180

ccaattgcct gccttgtgct gtggaatctg tacatctggc caacatgtgc ttgtgtgagc    240

ctgacagtgc attttccaga gcctcacctc ggctctgccc tggaggctct gtgctgctgg    300

aatcagactc aaggacctca tcagaggacc atggccccgt atcacctggg tcaggcactg    360

aagctgggac aggagagcag agacttccaa aatgagggat ccctgtgttc tgaggtgatc    420

atgactggga cccaaggact caagcgcatg ctccagaggg aatcgtttcc cacaaggcct    480

ttggcaggaa cagggatcct gggagcctgc caagcagagc gcacagtgtt cctggagtct    540

cgctgcccag atgccacgga atcagttgaa gccaggtctc cagctggggt ggacgtgccc    600

accagctgcc gaaggccaag acgccaggtc cggtggacgt gacaagcagg acatgacatg    660

gtccggtgtg acggcgagga cagaggaggc gcgtccggcc ttcctgaaca ccttaggctg    720

gtggggctgc ggcaagaagc gggtctgttt ctttacttcc tccacggagt cggcacacta    780

tggctgccct ctgggctccc agaacccaca acatgaaaga aatggtgcta cccagctcaa    840

gcctgggcct ttgaatccgg acacaaaacc ctctagcttg gaaatgaata tgctgcactt    900

tacaaccact gcactacctg actcaggaat cggctctgga aggtgaagct agaggaacca    960

gacctcatca gcccaacatc aaagacacca tcggaacagc agcgcccgca gcacccaccc   1020

cgcaccggcg actccatctt catggccacc ccctgcggcg gacggttgac caccagccac   1080

cacatcatcc cagagctgag ctcctccagc gggatgacgc cgtccccacc acctccctct   1140

tcttcttttt catccttctg tctctttgtt tctgagcttt cctgtctttc cttttttctg   1200

agagattcaa agcctccacg actctgtttc ccccgtccct tctgaattta atttgcacta   1260

agtcatttgc actggttgga gttgtggaga cggccttgag tctcagtacg agtgtgcgtg   1320

agtgtgagcc accttggcaa gtgcctgtgc agggcccggc cgccctccat ctgggccggg   1380

tgactgggcg ccggctgtgt gcccgaggcc tcaccctgcc ctcgcctagt ctggaagctc   1440

cgaccgacat cacggagcag ccttcaagca ttccattacg ccccatctcg ctctgtgccc   1500

ctccccacca gggcttcagc aggagccctg gactcatcat caataaacac tgttacagca   1560

att                                                                 1563


<210>  7639
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  7639

Met Gly Ile Asn Gly Val Cys Ala Leu Cys Gly Leu Cys Pro Ile Ala 
1               5                   10                  15


Cys Leu Val Leu Trp Asn Leu Tyr Ile Trp Pro Thr Cys Ala Cys Val 
            20                  25                  30


Ser Leu Thr Val His Phe Pro Glu Pro His Leu Gly Ser Ala Leu Glu 
        35                  40                  45


Ala Leu Cys Cys Trp Asn Gln Thr Gln Gly Pro His Gln Arg Thr Met 
    50                  55                  60


Ala Pro Tyr His Leu Gly Gln Ala Leu Lys Leu Gly Gln Glu Ser Arg 
65                  70                  75                  80


Asp Phe Gln Asn Glu Gly Ser Leu Cys Ser Glu Val Ile Met Thr Gly 
                85                  90                  95


Thr Gln Gly Leu Lys Arg Met Leu Gln Arg Glu Ser Phe Pro Thr Arg 
            100                 105                 110


Pro Leu Ala Gly Thr Gly Ile Leu Gly Ala Cys Gln Ala Glu Arg Thr 
        115                 120                 125


Val Phe Leu Glu Ser Arg Cys Pro Asp Ala Thr Glu Ser Val Glu Ala 
    130                 135                 140


Arg Ser Pro Ala Gly Val Asp Val Pro Thr Ser Cys Arg Arg Pro Arg 
145                 150                 155                 160


Arg Gln Val Arg Trp Thr 
                165


<210>  7640
<211>  459
<212>  DNA
<213>  Homo sapiens

<400>  7640
aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc     60

agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg    120

gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc    180

cgtccccacc acctccctct tcttcttttt catccttctg tctctttgtt tctgagcttt    240

cctgtctttc cttttttctg agagattcaa agcctccacg actctgtttc ccccgtccct    300

tctgaattta atttgcacct cgcctagtct ggaagctccg accgacatca cggagcagcc    360

ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct ccccaccagg gcttcagcag    420

gagccctgga ctcatcatca ataaacactg ttacagcaa                           459


<210>  7641
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7641

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7642
<211>  409
<212>  DNA
<213>  Homo sapiens

<400>  7642
aggtgaagct agaggaacca gacctcatca gcccaacatc aaagacacca tcggaacagc     60

agcgcccgca gcacccaccc cgcaccggcg actccatctt catggccacc ccctgcggcg    120

gacggttgac caccagccac cacatcatcc cagagctgag ctcctccagc gggatgacgc    180

cgtccccacc acctccctct tcttcttttt catccttctg tctctttgtt tctgagcttt    240

cctgtctttc cttttttctg agagattcaa agcctagtct ggaagctccg accgacatca    300

cggagcagcc ttcaagcatt ccattacgcc ccatctcgct ctgtgcccct ccccaccagg    360

gcttcagcag gagccctgga ctcatcatca ataaacactg ttacagcaa                409


<210>  7643
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  7643

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Ser Leu Glu Ala Pro Thr 
    50                  55                  60


Asp Ile Thr Glu Gln Pro Ser Ser Ile Pro Leu Arg Pro Ile Ser Leu 
65                  70                  75                  80


Cys Ala Pro Pro His Gln Gly Phe Ser Arg Ser Pro Gly Leu Ile Ile 
                85                  90                  95


Asn Lys His Cys Tyr 
            100


<210>  7644
<211>  372
<212>  DNA
<213>  Homo sapiens

<400>  7644
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc ctcaccctgc cctcgcctag    240

tctggaagct ccgaccgaca tcacggagca gccttcaagc attccattac gccccatctc    300

gctctgtgcc cctccccacc agggcttcag caggagccct ggactcatca tcaataaaca    360

ctgttacagc aa                                                        372


<210>  7645
<211>  66
<212>  PRT
<213>  Homo sapiens

<400>  7645

Leu Glu Ala Gly Leu Val Gly Pro Glu Ala Ser Glu Glu Cys Gly Val 
1               5                   10                  15


Gly Leu Thr Leu Pro Ser Pro Ser Leu Glu Ala Pro Thr Asp Ile Thr 
            20                  25                  30


Glu Gln Pro Ser Ser Ile Pro Leu Arg Pro Ile Ser Leu Cys Ala Pro 
        35                  40                  45


Pro His Gln Gly Phe Ser Arg Ser Pro Gly Leu Ile Ile Asn Lys His 
    50                  55                  60


Cys Tyr 
65


<210>  7646
<211>  1058
<212>  DNA
<213>  Homo sapiens

<400>  7646
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggca accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca    120

ccttggacat ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagg    180

gctggtgggg cctgaggcca gtgaggagtg tggagtaggc gcccaggcat cgtgcagaca    240

gggcgacatc agctggggac gatgggcctg agctagggct ggaaagaagg gggagccagg    300

cattcatccc ggtcactttt ggttacagga cgtggcagct ggttggacga ggggagctgg    360

tgggcagggt ttgatcccag ggcctgggca acggaggtgt agctggcagc agcgggcagg    420

tgaggacccc atctgccggg caggtgagtc ccttccctcc ccaggcctcg cttccccagc    480

cttctgaaag aaggaggttt aggggatcga gggctggcgg ggagaagcag acaccctccc    540

agcagagggg caggatgggg gcaggagagt tagcaaaggt gacatcttct cggggggagc    600

cgagactgcg caaggctggg gggttatggg cccgttccag gcagaaagag caagagggca    660

gggagggagc acaggggtgg ccagcgtagg gtccagcacg tggggtggta ccccaggcct    720

gggtcagaca gggacatggc aggggacaca ggacagaggg gtccccagct gccacctcac    780

ccaccgcaat tcatttagta gcaggcacag gggcagctcc ggcacggctt tctcaggcct    840

atgccggagc ctcgagggct ggagagcggg aagacaggca gtgctcgggg agttgcagca    900

ggacgcctca ccctgccctc gcctagtctg gaagctccga ccgacatcac ggagcagcct    960

tcaagcattc cattacgccc catctcgctc tgtgcccctc cccaccaggg cttcagcagg   1020

agccctggac tcatcatcaa taaacactgt tacagcaa                           1058


<210>  7647
<211>  143
<212>  PRT
<213>  Homo sapiens

<400>  7647

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Ala Ser Pro 
                85                  90                  95


Cys Pro Arg Leu Val Trp Lys Leu Arg Pro Thr Ser Arg Ser Ser Leu 
            100                 105                 110


Gln Ala Phe His Tyr Ala Pro Ser Arg Ser Val Pro Leu Pro Thr Arg 
        115                 120                 125


Ala Ser Ala Gly Ala Leu Asp Ser Ser Ser Ile Asn Thr Val Thr 
    130                 135                 140


<210>  7648
<211>  1274
<212>  DNA
<213>  Homo sapiens

<400>  7648
agttagaaaa agcccgggct aggaccgagg agcagggtga gggagggggt gggatgggtg     60

gggggtaacg ggggaaactg gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg    120

tgctggagga gagcttgtgg gagccaagga gcaccttgga catctggagt ctggcaggag    180

tgatgacggg tggaggggct agctcgaggc agggctggtg gggcctgagg ccagtgagga    240

gtgtggagta ggcgcccagg catcgtgcag acagggcgac atcagctggg gacgatgggc    300

ctgagctagg gctggaaaga agggggagcc aggcattcat cccggtcact tttggttaca    360

ggacgtggca gctggttgga cgaggggagc tggtgggcag ggtttgatcc cagggcctgg    420

gcaacggagg tgtagctggc agcagcgggc aggtgaggac cccatctgcc gggcaggtga    480

gtcccttccc tccccaggcc tcgcttcccc agccttctga aagaaggagg tttaggggat    540

cgagggctgg cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag    600

agttagcaaa ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat    660

gggcccgttc caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt    720

agggtccagc acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac    780

acaggacaga ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca    840

caggggcagc tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc    900

gggaagacag gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc    960

acgggagggg ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg   1020

cgccggtccc acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact   1080

tggtgacgct gtatgccctc accgctcagc ccctggggct ggcttggcag acagtacagc   1140

atccagggga ctccgaccga catcacggag cagccttcaa gcattccatt acgccccatc   1200

tcgctctgtg cccctcccca ccagggcttc agcaggagcc ctggactcat catcaataaa   1260

cactgttaca gcaa                                                     1274


<210>  7649
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  7649

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Leu Arg Pro Thr Ser Arg Ser Ser Leu Gln Ala Phe 
                165                 170                 175


His Tyr Ala Pro Ser Arg Ser Val Pro Leu Pro Thr Arg Ala Ser Ala 
            180                 185                 190


Gly Ala Leu Asp Ser Ser Ser Ile Asn Thr Val Thr 
        195                 200


<210>  7650
<211>  613
<212>  DNA
<213>  Homo sapiens

<400>  7650
agcgggtctg tttctttact tcctccacgg agtcggcaca ctatggctgc cctctgggct     60

cccagaaccc accccgcacc ggcgactcca tcttcatggc caccccctgc ggcggacggt    120

tgaccaccag ccaccacatc atcccagagc tgagctcctc cagcgggatg acgccgtccc    180

caccacctcc ctcttcttct ttttcatcct tctgtctctt tgtttctgag ctttcctgtc    240

tttccttttt tctgagagat tcaaagcctc cacgactctg tttcccccgt cccttctgaa    300

tttaatttgc actaagtcat ttgcactggt tggagttgtg gagacggcct tgagtctcag    360

tacgagtgtg cgtgagtgtg agccaccttg gcaagtgcct gtgcagggcc cggccgccct    420

ccatctgggc cgggtgactg ggcgccggct gtgtgcccga ggcctcaccc tgccctcgcc    480

tagtctggaa gctccgaccg acatcacgga gcagccttca agcattccat tacgccccat    540

ctcgctctgt gcccctcccc accagggctt cagcaggagc cctggactca tcatcaataa    600

acactgttac agc                                                       613


<210>  7651
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7651

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7652
<211>  633
<212>  DNA
<213>  Homo sapiens

<400>  7652
gaaactgggg aagtggggaa ccgaggggca accagacctc atcagcccaa catcaaagac     60

accatcggaa cagcagcgcc cgcagcaccc accccgcacc ggcgactcca tcttcatggc    120

caccccctgc ggcggacggt tgaccaccag ccaccacatc atcccagagc tgagctcctc    180

cagcgggatg acgccgtccc caccacctcc ctcttcttct ttttcatcct tctgtctctt    240

tgtttctgag ctttcctgtc tttccttttt tctgagagat tcaaagcctc cacgactctg    300

tttcccccgt cccttctgaa tttaatttgc actaagtcat ttgcactggt tggagttgtg    360

gagacggcct tgagtctcag tacgagtgtg cgtgagtgtg agccaccttg gcaagtgcct    420

gtgcagggcc cggccgccct ccatctgggc cgggtgactg ggcgccggct gtgtgcccga    480

ggcctcaccc tgccctcgcc tagtctggaa gctccgaccg acatcacgga gcagccttca    540

agcattccat tacgccccat ctcgctctgt gcccctcccc accagggctt cagcaggagc    600

cctggactca tcatcaataa acactgttac agc                                 633


<210>  7653
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7653

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7654
<211>  652
<212>  DNA
<213>  Homo sapiens

<400>  7654
agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa ccgaggggca     60

accaggggaa gatggggtgc tggaggagag cttgtgggag ccaaggagca ccttggacat    120

ctggagtctg gcaggagtga tgacgggtgg aggggctagc tcgaggcagc caccacatca    180

tcccagagct gagctcctcc agcgggatga cgccgtcccc accacctccc tcttcttctt    240

tttcatcctt ctgtctcttt gtttctgagc tttcctgtct ttcctttttt ctgagagatt    300

caaagcctcc acgactctgt ttcccccgtc ccttctgaat ttaatttgca ctaagtcatt    360

tgcactggtt ggagttgtgg agacggcctt gagtctcagt acgagtgtgc gtgagtgtga    420

gccaccttgg caagtgcctg tgcagggccc ggccgccctc catctgggcc gggtgactgg    480

gcgccggctg tgtgcccgag gcctcaccct gccctcgcct agtctggaag ctccgaccga    540

catcacggag cagccttcaa gcattccatt acgccccatc tcgctctgtg cccctcccca    600

ccagggcttc agcaggagcc ctggactcat catcaataaa cactgttaca gc            652


<210>  7655
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7655

Met Thr Gly Gly Gly Ala Ser Ser Arg Gln Pro Pro His His Pro Arg 
1               5                   10                  15


Ala Glu Leu Leu Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe 
            20                  25                  30


Phe Phe Phe Ile Leu Leu Ser Leu Cys Phe 
        35                  40


<210>  7656
<211>  1603
<212>  DNA
<213>  Homo sapiens

<400>  7656
gtgagggagg gggtgggatg ggtggggggt aacgggggaa actggggaag tggggaaccg     60

aggggcaacc aggggaagat ggggtgctgg aggagagctt gtgggagcca aggagcacct    120

tggacatctg gagtctggca ggagtgatga cgggtggagg ggctagctcg aggcagggct    180

ggtggggcct gaggccagtg aggagtgtgg agtaggcgcc caggcatcgt gcagacaggg    240

cgacatcagc tggggacgat gggcctgagc tagggctgga aagaaggggg agccaggcat    300

tcatcccggt cacttttggt tacaggacgt ggcagctggt tggacgaggg gagctggtgg    360

gcagggtttg atcccagggc ctgggcaacg gaggtgtagc tggcagcagc gggcaggtga    420

ggaccccatc tgccgggcag gtgagtccct tccctcccca ggcctcgctt ccccagcctt    480

ctgaaagaag gaggtttagg ggatcgaggg ctggcgggga gaagcagaca ccctcccagc    540

agaggggcag gatgggggca ggagagttag caaaggtgac atcttctcgg ggggagccga    600

gactgcgcaa ggctgggggg ttatgggccc gttccaggca gaaagagcaa gagggcaggg    660

agggagcaca ggggtggcca gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg    720

tcagacaggg acatggcagg ggacacagga cagaggggtc cccagctgcc acctcaccca    780

ccgcaattca tttagtagca ggcacagggg cagctccggc acggctttct caggcctatg    840

ccggagcctc gagggctgga gagcgggaag acaggcagtg ctcggggagt tgcagcagga    900

cgtcaccagg agggcgaagc ggccacggga ggggggcccc gggacattgc gcagcaagga    960

ggctgcaggg gctcggcctg cgggcgccgg tcccacgagg cactgcggcc cagggtctgg   1020

tgcggagagg gcccacagtg gacttggtga cgctgtatgc cctcaccgct cagcccctgg   1080

ggctggcttg gcagacagta cagcatccag gggagtcaag ggcatggggc gagaccaagc   1140

tgagctcctc cagcgggatg acgccgtccc caccacctcc ctcttcttct ttttcatcct   1200

tctgtctctt tgtttctgag ctttcctgtc tttccttttt tctgagagat tcaaagcctc   1260

cacgactctg tttcccccgt cccttctgaa tttaatttgc actaagtcat ttgcactggt   1320

tggagttgtg gagacggcct tgagtctcag tacgagtgtg cgtgagtgtg agccaccttg   1380

gcaagtgcct gtgcagggcc cggccgccct ccatctgggc cgggtgactg ggcgccggct   1440

gtgtgcccga ggcctcaccc tgccctcgcc tagtctggaa gctccgaccg acatcacgga   1500

gcagccttca agcattccat tacgccccat ctcgctctgt gcccctcccc accagggctt   1560

cagcaggagc cctggactca tcatcaataa acactgttac agc                     1603


<210>  7657
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  7657

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Ala Glu Leu Leu 
                165                 170                 175


Gln Arg Asp Asp Ala Val Pro Thr Thr Ser Leu Phe Phe Phe Phe Ile 
            180                 185                 190


Leu Leu Ser Leu Cys Phe 
        195


<210>  7658
<211>  720
<212>  DNA
<213>  Homo sapiens

<400>  7658
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagagctga gctcctccag cgggatgacg ccgtccccac cacctccctc    300

ttcttctttt tcatccttct gtctctttgt ttctgagctt tcctgtcttt ccttttttct    360

gagagattca aagcctccac gactctgttt cccccgtccc ttctgaattt aatttgcact    420

aagtcatttg cactggttgg agttgtggag acggccttga gtctcagtac gagtgtgcgt    480

gagtgtgagc caccttggca agtgcctgtg cagggcccgg ccgccctcca tctgggccgg    540

gtgactgggc gccggctgtg tgcccgaggc ctcaccctgc cctcgcctag tctggaagct    600

ccgaccgaca tcacggagca gccttcaagc attccattac gccccatctc gctctgtgcc    660

cctccccacc agggcttcag caggagccct ggactcatca tcaataaaca ctgttacagc    720


<210>  7659
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7659

Met Thr Pro Ser Pro Pro Pro Pro Ser Ser Ser Phe Ser Ser Phe Cys 
1               5                   10                  15


Leu Phe Val Ser Glu Leu Ser Cys Leu Ser Phe Phe Leu Arg Asp Ser 
            20                  25                  30


Lys Pro Pro Arg Leu Cys Phe Pro Arg Pro Phe 
        35                  40


<210>  7660
<211>  787
<212>  DNA
<213>  Homo sapiens

<400>  7660
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac tccatcttca tggccacccc ctgcggcgga cggttgacca    300

ccagccacca catcatccca gagctgagct cctccagcgg gatgacgccg tccccaccac    360

ctccctcttc ttctttttca tccttctgtc tctttgtttc tgagctttcc tgtctttcct    420

tttttctgag agattcaaag cctccacgac tctgtttccc ccgtcccttc tgaatttaat    480

ttgcactaag tcatttgcac tggttggagt tgtggagacg gccttgagtc tcagtacgag    540

tgtgcgtgag tgtgagccac cttggcaagt gcctgtgcag ggcccggccg ccctccatct    600

gggccgggtg actgggcgcc ggctgtgtgc ccgaggcctc accctgccct cgcctagtct    660

ggaagctccg accgacatca cggagcagcc ttcaagcatt ccattacgcc ccatctcgct    720

ctgtgcccct ccccaccagg gcttcagcag gagccctgga ctcatcatca ataaacactg    780

ttacagc                                                              787


<210>  7661
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  7661

Met Ala Thr Pro Cys Gly Gly Arg Leu Thr Thr Ser His His Ile Ile 
1               5                   10                  15


Pro Glu Leu Ser Ser Ser Ser Gly Met Thr Pro Ser Pro Pro Pro Pro 
            20                  25                  30


Ser Ser Ser Phe Ser Ser Phe Cys Leu Phe Val Ser Glu Leu Ser Cys 
        35                  40                  45


Leu Ser Phe Phe Leu Arg Asp Ser Lys Pro Pro Arg Leu Cys Phe Pro 
    50                  55                  60


Arg Pro Phe 
65


<210>  7662
<211>  928
<212>  DNA
<213>  Homo sapiens

<400>  7662
agggtgaggg agggggtggg atgggtgggg ggtaacgggg gaaactgggg aagtggggaa     60

ccgaggggcc tcgcttcccc agccttctga aagaaggagg tttaggggat cgagggctgg    120

cggggagaag cagacaccct cccagcagag gggcaggatg ggggcaggag agttagcaaa    180

ggtgacatct tctcgggggg agccgagact gcgcaaggct ggggggttat gggcccgttc    240

caggcagaaa gagcaagagg gcagggaggg agcacagggg tggccagcgt agggtccagc    300

acgtggggtg gtaccccagg cctgggtcag acagggacat ggcaggggac acaggacaga    360

ggggtcccca gctgccacct cacccaccgc aattcattta gtagcaggca caggggcagc    420

tccggcacgg ctttctcagg cctatgccgg agcctcgagg gctggagagc gggaagacag    480

gcagtgctcg gggagttgca gcaggacgtc accaggaggg cgaagcggcc acgggagggg    540

ggccccggga cattgcgcag caaggaggct gcaggggctc ggcctgcggg cgccggtccc    600

acgaggcact gcggcccagg gtctggtgcg gagagggccc acagtggact tggtgacgct    660

gtatgccctc accgctcagc ccctggggct ggcttggcag acagtacagc atccagggga    720

gtcaagggca tggggcgaga ccagactagg cgaggcgggc ggggcggagt gaatgagctc    780

tcaggaggga ggatggtgca ggcaggggtg aggagcgcag cgggcggcga gcgggaggca    840

ctggcctcca gagcccgtgg ccaaggcggg cctcgcgggc ggcgacggag ccgggatcgg    900

tgcctcagcg ttcgggctgg agacgagg                                       928


<210>  7663
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  7663

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp 
225                 230


<210>  7664
<211>  996
<212>  DNA
<213>  Homo sapiens

<400>  7664
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcact tttggttaca ggacgtggca gctggttgga    360

cgaggggagc tggtgggcag ggtttgatcc cagggcagac agggacatgg caggggacac    420

aggacagagg ggtccccagc tgccacctca cccaccgcaa ttcatttagt agcaggcaca    480

ggggcagctc cggcacggct ttctcaggcc tatgccggag cctcgagggc tggagagcgg    540

gaagacaggc agtgctcggg gagttgcagc aggacgtcac caggagggcg aagcggccac    600

gggagggggg ccccgggaca ttgcgcagca aggaggctgc aggggctcgg cctgcgggcg    660

ccggtcccac gaggcactgc ggcccagggt ctggtgcgga gagggcccac agtggacttg    720

gtgacgctgt atgccctcac cgctcagccc ctggggctgg cttggcagac agtacagcat    780

ccaggggagt caagggcatg gggcgagacc agactaggcg aggcgggcgg ggcggagtga    840

atgagctctc aggagggagg atggtgcagg caggggtgag gagcgcagcg ggcggcgagc    900

gggaggcact ggcctccaga gcccgtggcc aaggcgggcc tcgcgggcgg cgacggagcc    960

gggatcggtg cctcagcgtt cgggctggag acgagg                              996


<210>  7665
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7665

Met Pro Glu Pro Arg Gly Leu Glu Ser Gly Lys Thr Gly Ser Ala Arg 
1               5                   10                  15


Gly Val Ala Ala Gly Arg His Gln Glu Gly Glu Ala Ala Thr Gly Gly 
            20                  25                  30


Gly Pro Arg Asp Ile Ala Gln Gln Gly Gly Cys Arg Gly Ser Ala Cys 
        35                  40                  45


Gly Arg Arg Ser His Glu Ala Leu Arg Pro Arg Val Trp Cys Gly Glu 
    50                  55                  60


Gly Pro Gln Trp Thr Trp 
65                  70


<210>  7666
<211>  1002
<212>  DNA
<213>  Homo sapiens

<400>  7666
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggtgac atcttctcgg ggggagccga gactgcgcaa ggctgggggg    300

ttatgggccc gttccaggca gaaagagcaa gagggcaggg agggagcaca ggggtggcca    360

gcgtagggtc cagcacgtgg ggtggtaccc caggcctggg tcagacaggg acatggcagg    420

ggacacagga cagaggggtc cccagctgcc acctcaccca ccgcaattca tttagtagca    480

ggcacagggg cagctccggc acggctttct caggcctatg ccggagcctc gagggctgga    540

gagcgggaag acaggcagtg ctcggggagt tgcagcagga cgtcaccagg agggcgaagc    600

ggccacggga ggggggcccc gggacattgc gcagcaagga ggctgcaggg gctcggcctg    660

cgggcgccgg tcccacgagg cactgcggcc cagggtctgg tgcggagagg gcccacagtg    720

gacttggtga cgctgtatgc cctcaccgct cagcccctgg ggctggcttg gcagacagta    780

cagcatccag gggagtcaag ggcatggggc gagaccagac taggcgaggc gggcggggcg    840

gagtgaatga gctctcagga gggaggatgg tgcaggcagg ggtgaggagc gcagcgggcg    900

gcgagcggga ggcactggcc tccagagccc gtggccaagg cgggcctcgc gggcggcgac    960

ggagccggga tcggtgcctc agcgttcggg ctggagacga gg                      1002


<210>  7667
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  7667

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp 
225                 230


<210>  7668
<211>  995
<212>  DNA
<213>  Homo sapiens

<400>  7668
aggaccgagg agcagggtga gggagggggt gggatgggtg gggggtaacg ggggaaactg     60

gggaagtggg gaaccgaggg gcaaccaggg gaagatgggg tgctggagga gagcttgtgg    120

gagccaagga gcaccttgga catctggagt ctggcaggag tgatgacggg tggaggggct    180

agctcgaggc agggctggtg gggcctgagg ccagtgagga gtgtggagta ggcgcccagg    240

catcgtgcag acagggcgac atcagctggg gacgatgggc ctgagctagg gctggaaaga    300

agggggagcc aggcattcat cccggtcact tttggttaca ggacgggtgg ccagcgtagg    360

gtccagcacg tggggtggta ccccaggcct gggtcagaca gggacatggc aggggacaca    420

ggacagaggg gtccccagct gccacctcac ccaccgcaat tcatttagta gcaggcacag    480

gggcagctcc ggcacggctt tctcaggcct atgccggagc ctcgagggct ggagagcggg    540

aagacaggca gtgctcgggg agttgcagca ggacgtcacc aggagggcga agcggccacg    600

ggaggggggc cccgggacat tgcgcagcaa ggaggctgca ggggctcggc ctgcgggcgc    660

cggtcccacg aggcactgcg gcccagggtc tggtgcggag agggcccaca gtggacttgg    720

tgacgctgta tgccctcacc gctcagcccc tggggctggc ttggcagaca gtacagcatc    780

caggggagtc aagggcatgg ggcgagacca gactaggcga ggcgggcggg gcggagtgaa    840

tgagctctca ggagggagga tggtgcaggc aggggtgagg agcgcagcgg gcggcgagcg    900

ggaggcactg gcctccagag cccgtggcca aggcgggcct cgcgggcggc gacggagccg    960

ggatcggtgc ctcagcgttc gggctggaga cgagg                               995


<210>  7669
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  7669

Met Pro Glu Pro Arg Gly Leu Glu Ser Gly Lys Thr Gly Ser Ala Arg 
1               5                   10                  15


Gly Val Ala Ala Gly Arg His Gln Glu Gly Glu Ala Ala Thr Gly Gly 
            20                  25                  30


Gly Pro Arg Asp Ile Ala Gln Gln Gly Gly Cys Arg Gly Ser Ala Cys 
        35                  40                  45


Gly Arg Arg Ser His Glu Ala Leu Arg Pro Arg Val Trp Cys Gly Glu 
    50                  55                  60


Gly Pro Gln Trp Thr Trp 
65                  70


<210>  7670
<211>  1033
<212>  DNA
<213>  Homo sapiens

<400>  7670
agttagaaaa agcccgggct aggaccgagg agcagggacg tggcagctgg ttggacgagg     60

ggagctggtg ggcagggttt gatcccaggg cctgggcaac ggaggtgtag ctggcagcag    120

cgggcaggtg aggaccccat ctgccgggca ggtgagtccc ttccctcccc aggcctcgct    180

tccccagcct tctgaaagaa ggaggtttag gggatcgagg gctggcgggg agaagcagac    240

accctcccag cagaggggca ggatgggggc aggagagtta gcaaaggtga catcttctcg    300

gggggagccg agactgcgca aggctggggg gttatgggcc cgttccaggc agaaagagca    360

agagggcagg gagggagcac aggggtggcc agcgtagggt ccagcacgtg gggtggtacc    420

ccaggcctgg gtcagacagg gacatggcag gggacacagg acagaggggt ccccagctgc    480

cacctcaccc accgcaattc atttagtagc aggcacaggg gcagctccgg cacggctttc    540

tcaggcctat gccggagcct cgagggctgg agagcgggaa gacaggcagt gctcggggag    600

ttgcagcagg acgtcaccag gagggcgaag cggccacggg aggggggccc cgggacattg    660

cgcagcaagg aggctgcagg ggctcggcct gcgggcgccg gtcccacgag gcactgcggc    720

ccagggtctg gtgcggagag ggcccacagt ggacttggtg acgctgtatg ccctcaccgc    780

tcagcccctg gggctggctt ggcagacagt acagcatcca ggggagtcaa gggcatgggg    840

cgagaccaga ctaggcgagg cgggcggggc ggagtgaatg agctctcagg agggaggatg    900

gtgcaggcag gggtgaggag cgcagcgggc ggcgagcggg aggcactggc ctccagagcc    960

cgtggccaag gcgggcctcg cgggcggcga cggagccggg atcggtgcct cagcgttcgg   1020

gctggagacg agg                                                      1033


<210>  7671
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  7671

Met Gly Pro Phe Gln Ala Glu Arg Ala Arg Gly Gln Gly Gly Ser Thr 
1               5                   10                  15


Gly Val Ala Ser Val Gly Ser Ser Thr Trp Gly Gly Thr Pro Gly Leu 
            20                  25                  30


Gly Gln Thr Gly Thr Trp Gln Gly Thr Gln Asp Arg Gly Val Pro Ser 
        35                  40                  45


Cys His Leu Thr His Arg Asn Ser Phe Ser Ser Arg His Arg Gly Ser 
    50                  55                  60


Ser Gly Thr Ala Phe Ser Gly Leu Cys Arg Ser Leu Glu Gly Trp Arg 
65                  70                  75                  80


Ala Gly Arg Gln Ala Val Leu Gly Glu Leu Gln Gln Asp Val Thr Arg 
                85                  90                  95


Arg Ala Lys Arg Pro Arg Glu Gly Gly Pro Gly Thr Leu Arg Ser Lys 
            100                 105                 110


Glu Ala Ala Gly Ala Arg Pro Ala Gly Ala Gly Pro Thr Arg His Cys 
        115                 120                 125


Gly Pro Gly Ser Gly Ala Glu Arg Ala His Ser Gly Leu Gly Asp Ala 
    130                 135                 140


Val Cys Pro His Arg Ser Ala Pro Gly Ala Gly Leu Ala Asp Ser Thr 
145                 150                 155                 160


Ala Ser Arg Gly Val Lys Gly Met Gly Arg Asp Gln Thr Arg Arg Gly 
                165                 170                 175


Gly Arg Gly Gly Val Asn Glu Leu Ser Gly Gly Arg Met Val Gln Ala 
            180                 185                 190


Gly Val Arg Ser Ala Ala Gly Gly Glu Arg Glu Ala Leu Ala Ser Arg 
        195                 200                 205


Ala Arg Gly Gln Gly Gly Pro Arg Gly Arg Arg Arg Ser Arg Asp Arg 
    210                 215                 220


Cys Leu Ser Val Arg Ala Gly Asp 
225                 230


<210>  7672
<211>  1568
<212>  DNA
<213>  Homo sapiens

<400>  7672
gctaatttag gagcttgaga tgctaaagag ctgggagtgc cactgctgct ttattctggg     60

gtctaggatc cttgtgttgg ctgagataat ctgctaatgt gggtgcagca gacatcccgc    120

ggtttgtgga atcgataaag gatggggatc aatggtgttt gtgcactgtg cggtctgtgc    180

ccaattgcct gccttgtgct gtggaatctg tacatctggc caacatgtgc ttgtgtgagc    240

ctgacagtgc attttccaga gcctcacctc ggctctgccc tggaggctct gtgctgctgg    300

aatcagactc aaggacctca tcagaggacc atggccccgt atcacctggg tcaggcactg    360

aagctgggac aggagagcag agacttccaa aatgagggat ccctgtgttc tgaggtgatc    420

atgactggga cccaaggact caagcgcatg ctccagaggg aatcgtttcc cacaaggcct    480

ttggcaggaa cagggatcct gggagcctgc caagcagagc gcacagtgtt cctggagtct    540

cgctgcccag atgccacgga atcagttgaa ggacgtggca gctggttgga cgaggggagc    600

tggtgggcag ggtttgatcc cagggcctgg gcaacggagg tgtagctggc agcagcgggc    660

aggtgaggac cccatctgcc gggcaggtga gtcccttccc tccccaggcc tcgcttcccc    720

agccttctga aagaaggagg tttaggggat cgagggctgg cggggagaag cagacaccct    780

cccagcagag gggcaggatg ggggcaggag agttagcaaa ggtgacatct tctcgggggg    840

agccgagact gcgcaaggct ggggggttat gggcccgttc caggcagaaa gagcaagagg    900

gcagggaggg agcacagggg tggccagcgt agggtccagc acgtggggtg gtaccccagg    960

cctgggtcag acagggacat ggcaggggac acaggacaga ggggtcccca gctgccacct   1020

cacccaccgc aattcattta gtagcaggca caggggcagc tccggcacgg ctttctcagg   1080

cctatgccgg agcctcgagg gctggagagc gggaagacag gcagtgctcg gggagttgca   1140

gcaggacgtc accaggaggg cgaagcggcc acgggagggg ggccccggga cattgcgcag   1200

caaggaggct gcaggggctc ggcctgcggg cgccggtccc acgaggcact gcggcccagg   1260

gtctggtgcg gagagggccc acagtggact tggtgacgct gtatgccctc accgctcagc   1320

ccctggggct ggcttggcag acagtacagc atccagggga gtcaagggca tggggcgaga   1380

ccagactagg cgaggcgggc ggggcggagt gaatgagctc tcaggaggga ggatggtgca   1440

ggcaggggtg aggagcgcag cgggcggcga gcgggaggca ctggcctcca gagcccgtgg   1500

ccaaggcggg cctcgcgggc ggcgacggag ccgggatcgg tgcctcagcg ttcgggctgg   1560

agacgagg                                                            1568


<210>  7673
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7673

Met Gly Ile Asn Gly Val Cys Ala Leu Cys Gly Leu Cys Pro Ile Ala 
1               5                   10                  15


Cys Leu Val Leu Trp Asn Leu Tyr Ile Trp Pro Thr Cys Ala Cys Val 
            20                  25                  30


Ser Leu Thr Val His Phe Pro Glu Pro His Leu Gly Ser Ala Leu Glu 
        35                  40                  45


Ala Leu Cys Cys Trp Asn Gln Thr Gln Gly Pro His Gln Arg Thr Met 
    50                  55                  60


Ala Pro Tyr His Leu Gly Gln Ala Leu Lys Leu Gly Gln Glu Ser Arg 
65                  70                  75                  80


Asp Phe Gln Asn Glu Gly Ser Leu Cys Ser Glu Val Ile Met Thr Gly 
                85                  90                  95


Thr Gln Gly Leu Lys Arg Met Leu Gln Arg Glu Ser Phe Pro Thr Arg 
            100                 105                 110


Pro Leu Ala Gly Thr Gly Ile Leu Gly Ala Cys Gln Ala Glu Arg Thr 
        115                 120                 125


Val Phe Leu Glu Ser Arg Cys Pro Asp Ala Thr Glu Ser Val Glu Gly 
    130                 135                 140


Arg Gly Ser Trp Leu Asp Glu Gly Ser Trp Trp Ala Gly Phe Asp Pro 
145                 150                 155                 160


Arg Ala Trp Ala Thr Glu Val 
                165


<210>  7674
<211>  1143
<212>  DNA
<213>  Homo sapiens

<400>  7674
atggcactgt ccaaagatgc ccagatcact gaatgcacag catgcagaag ggctgaatcg     60

agggtcacgt ggcgggggct gctggtgtgg gccatgctcc ccaaacccca ggcagcacag    120

aggtcaccag gtctccaggg ctgtccctcc agggccgtcc ctccagggct gtccctccag    180

ggcctttaca gatcccgagt cctgactcct cacacacaga gcgtgggcct gggagtagga    240

gtccaggcac cccgggccca gggccctgca tcttccctcc ccagccagac tcacagcacc    300

agccagactc acagcaccag cccttgggcc acgggggcgg caggcccagc ttcagaggcg    360

cagtggctgt cccggcctct ggtcggtctc gctaggggcc gcctctcccc acagaccagg    420

gcctcccttt gggtgggtgc tgcctcacaa gggagcctca gtgggcactg gcccggctct    480

gcttctggga tgaggttgag tgagcacatg ggggtccctg caaggtccag ggccaaggca    540

gagacacaga agcagaggga gatgggtctc catcgtcgcc caggcccctt gagagacctc    600

cacccccgcc agagcctgtg gacagctgag caggagctgc ccccgcatcc tgcagtggga    660

gcggagggtc ggccagcacg ggcaaccgac aggagccggc ccggcccctc catcctcctt    720

cggtgcgggg ctgaggaggc ctctgtctgg tcaggctgct ggacacccaa ggctcgagag    780

gaagccatgg ctttggaggg tggcattagc acggagggga gccggcggcc cacgggcatc    840

gtgcacaccc agcacagcgg tggcaccaag cctgccctga gggctggttc tgggatgggc    900

agaagtggct cctgcggagt ggcaggagag aaaggcaggt gtgccctccc ggctcaggcc    960

tctccgcacc tgaaggtcca gaggggaggc agcccccaga aggctgcacg ggcggggctt   1020

acagacaggg ctccgggacc aaggtgtggg cctcagggac agcagacagc agggagggaa   1080

gagggggaag acggggcttc tgctgaggga gatggcccct cgctggacga agggcagttc   1140

tag                                                                 1143


<210>  7675
<211>  380
<212>  PRT
<213>  Homo sapiens

<400>  7675

Met Ala Leu Ser Lys Asp Ala Gln Ile Thr Glu Cys Thr Ala Cys Arg 
1               5                   10                  15


Arg Ala Glu Ser Arg Val Thr Trp Arg Gly Leu Leu Val Trp Ala Met 
            20                  25                  30


Leu Pro Lys Pro Gln Ala Ala Gln Arg Ser Pro Gly Leu Gln Gly Cys 
        35                  40                  45


Pro Ser Arg Ala Val Pro Pro Gly Leu Ser Leu Gln Gly Leu Tyr Arg 
    50                  55                  60


Ser Arg Val Leu Thr Pro His Thr Gln Ser Val Gly Leu Gly Val Gly 
65                  70                  75                  80


Val Gln Ala Pro Arg Ala Gln Gly Pro Ala Ser Ser Leu Pro Ser Gln 
                85                  90                  95


Thr His Ser Thr Ser Gln Thr His Ser Thr Ser Pro Trp Ala Thr Gly 
            100                 105                 110


Ala Ala Gly Pro Ala Ser Glu Ala Gln Trp Leu Ser Arg Pro Leu Val 
        115                 120                 125


Gly Leu Ala Arg Gly Arg Leu Ser Pro Gln Thr Arg Ala Ser Leu Trp 
    130                 135                 140


Val Gly Ala Ala Ser Gln Gly Ser Leu Ser Gly His Trp Pro Gly Ser 
145                 150                 155                 160


Ala Ser Gly Met Arg Leu Ser Glu His Met Gly Val Pro Ala Arg Ser 
                165                 170                 175


Arg Ala Lys Ala Glu Thr Gln Lys Gln Arg Glu Met Gly Leu His Arg 
            180                 185                 190


Arg Pro Gly Pro Leu Arg Asp Leu His Pro Arg Gln Ser Leu Trp Thr 
        195                 200                 205


Ala Glu Gln Glu Leu Pro Pro His Pro Ala Val Gly Ala Glu Gly Arg 
    210                 215                 220


Pro Ala Arg Ala Thr Asp Arg Ser Arg Pro Gly Pro Ser Ile Leu Leu 
225                 230                 235                 240


Arg Cys Gly Ala Glu Glu Ala Ser Val Trp Ser Gly Cys Trp Thr Pro 
                245                 250                 255


Lys Ala Arg Glu Glu Ala Met Ala Leu Glu Gly Gly Ile Ser Thr Glu 
            260                 265                 270


Gly Ser Arg Arg Pro Thr Gly Ile Val His Thr Gln His Ser Gly Gly 
        275                 280                 285


Thr Lys Pro Ala Leu Arg Ala Gly Ser Gly Met Gly Arg Ser Gly Ser 
    290                 295                 300


Cys Gly Val Ala Gly Glu Lys Gly Arg Cys Ala Leu Pro Ala Gln Ala 
305                 310                 315                 320


Ser Pro His Leu Lys Val Gln Arg Gly Gly Ser Pro Gln Lys Ala Ala 
                325                 330                 335


Arg Ala Gly Leu Thr Asp Arg Ala Pro Gly Pro Arg Cys Gly Pro Gln 
            340                 345                 350


Gly Gln Gln Thr Ala Gly Arg Glu Glu Gly Glu Asp Gly Ala Ser Ala 
        355                 360                 365


Glu Gly Asp Gly Pro Ser Leu Asp Glu Gly Gln Phe 
    370                 375                 380


<210>  7676
<211>  988
<212>  DNA
<213>  Homo sapiens

<400>  7676
cttagcttta tgcgctcaga aaccaaatta aacccccccc ccatgtaaca ggggggcagt     60

gacaaaagca agaacgcacg aagccagcct ggagaccacc acgtcctgcc ccccgccatt    120

tatcgccctg attggatttt gtttttcatc tgtccctgtt gcttgggttg agttgagggt    180

ggagcctcct ggggggcact ggccactgag cccccttgga gaagtcagag gggagtggag    240

aaggccactg tccggcctgg cttctgggga cagtggctgg tccccagaag tcctgagggc    300

ggaggggggg gttgggcagg gtctcctcag gtgtcaggag ggtgctcgga ggccacagga    360

gggggctcct ggctggcctg aggctggccg gaggggaagg ggctagcagg tgtgtaaaca    420

gagggttcca tcaggctggg gcagggtggc cgccttccgc acacttgagg aaccctcccc    480

tctccctcgg tgacatcttg cccgcccctc agcaccctgc cttgtctcca ggaggtccga    540

agctctgtgg gacctcttgg gggcaaggtg gggtgaggcc ggggagtagg gaggtcaggc    600

gggtctgagc ccacagagca ggagagctgc caggtctgcc catcgaccag gtttgcagct    660

ctcccctggg ccactaacca tcctggcccg ggctgcctgt ctgacctccg tgcctagtcg    720

tggctctcca tcttgtctcc tccccgtgtc cccaatgtct tcagtggggg gccccctctt    780

gggtcccctc ctctgccatc acctgaagac ccccacgcca aacactgaat gtcacctgtg    840

cctgccgcct cggtccacct tgcggcccgt gtttgactca actcaactcc tttaacgcta    900

atatttccgg caaaatccca tgcttgggtt ttgtctttaa ccttgtaacg cttgcaatcc    960

caataaagca ttaaaagtca tgatcttc                                       988


<210>  7677
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  7677

Met Ser Ser Val Gly Gly Pro Leu Leu Gly Pro Leu Leu Cys His His 
1               5                   10                  15


Leu Lys Thr Pro Thr Pro Asn Thr Glu Cys His Leu Cys Leu Pro Pro 
            20                  25                  30


Arg Ser Thr Leu Arg Pro Val Phe Asp Ser Thr Gln Leu Leu 
        35                  40                  45


<210>  7678
<211>  1176
<212>  DNA
<213>  Homo sapiens

<400>  7678
atttcatgtc aattgatcta ttccccctct ttgtttcttg gggcattttt cctttttttt     60

ttttttttgt ttttttttta cccctcctta gctttatgcg ctcagaaacc aaattaaacc    120

ccccccccat gtaacagggg ggcagtgaca aaagcaagaa cgcacgaagc cagcctggag    180

accaccacgt cctgcccccc gccatttatc gccctgattg gattttgttt ttcatctgtc    240

cctgttgctt gggttgagtt gagggtggag cctcctgggg ggcactggcc actgagcccc    300

cttggagaag tcagagggga gtggagaagg ccactgtccg gcctggcttc tggggacagt    360

ggctggtccc cagaagtcct gagggcggag gggggggttg ggcagggtct cctcaggtgt    420

caggagggtg ctcggaggcc acaggagggg gctcctggct ggcctgaggc tggccggagg    480

ggaaggggct agcaggtgtg taaacagagg gttccatcag gctggggcag ggtggccgcc    540

ttccgcacac ttgaggaacc ctcccctctc cctcggtgac atcttgcccg cccctcagca    600

ccctgccttg tctccaggag gtccgaagct ctgtgggacc tcttgggggc aaggtggggt    660

gaggccgggg agtagggagg tcaggcgggt ctgagcccac agagcaggag agctgccagg    720

tctgcccatc gaccaggttg cttgggcccc ggagcccacg ggtctggtga tgccatagca    780

gccaccaccg cggcgcctag ggctgcggca gggactcggc ctctgggagg tttacctcgc    840

ccccacttgt gcccccagct cagcccccct gcacgcagcc cgactagcag tctagaggcc    900

tgaggcttct gggtcctggt gacggggctg gcatgacccc gggggtcgtc catgccagtc    960

cgcctcttgg gtcccctcct ctgccatcac ctgaagaccc ccacgccaaa cactgaatgt   1020

cacctgtgcc tgccgcctcg gtccaccttg cggcccgtgt ttgactcaac tcaactcctt   1080

taacgctaat atttccggca aaatcccatg cttgggtttt gtctttaacc ttgtaacgct   1140

tgcaatccca ataaagcatt aaaagtcatg atcttc                             1176


<210>  7679
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  7679

Met Pro Val Arg Leu Leu Gly Pro Leu Leu Cys His His Leu Lys Thr 
1               5                   10                  15


Pro Thr Pro Asn Thr Glu Cys His Leu Cys Leu Pro Pro Arg Ser Thr 
            20                  25                  30


Leu Arg Pro Val Phe Asp Ser Thr Gln Leu Leu 
        35                  40


<210>  7680
<211>  1149
<212>  DNA
<213>  Homo sapiens

<400>  7680
ggctgggcgg ggggagttct ggggtaggaa gtggtcccgg gagattttgg atggaaaagt     60

caggaggatt gacagcagac ttgcagaatt acatagagaa attaggaacc cccaaatttc    120

atgtcaattg atctattccc cctctttgtt tcttggggca tttttccttt tttttttttt    180

tttgtttttt ttttacccct ccttagcttt atgcgctcag aaaccaaatt aaaccccccc    240

cccatgtaac aggggggcag tgacaaaagc aagaacgcac gaagccagcc tggagaccac    300

cacgtcctgc cccccgccat ttatcgccct gattggattt tgtttttcat ctgtccctgt    360

tgcttgggtt gagttgaggg tggagcctcc tggggggcac tggccactga gcccccttgg    420

agaagtcaga ggggagtgga gaaggccact gtccggcctg gcttctgggg acagtggctg    480

gtccccagaa gtcctgaggg cggagggggg ggttgggcag ggtctcctca ggtgtcagga    540

gggtgctcgg aggccacagg agggggctcc tggctggcct gaggctggcc ggaggggaag    600

gggctagcag gtgtgtaaac agagggttcc atcaggctgg ggcagggtgg ccgccttccg    660

cacacttgag gaaccctccc ctctccctcg gtgacatctt gcccgcccct cagcaccctg    720

ccttgtctcc aggaggtccg aagctctgtg ggacctcttg ggggcaaggt ggggtgaggc    780

cggggagtag ggaggtcagg cgggtctgag cccacagagc aggagagctg ccaggtctgc    840

ccatcgacca ggttgcttgg gccccggagc ccacgggtct ggtgatgcca tagcagccac    900

caccgcggcg cctagggctg cggcagggac tcggccttct tgggtcccct cctctgccat    960

cacctgaaga cccccacgcc aaacactgaa tgtcacctgt gcctgccgcc tcggtccacc   1020

ttgcggcccg tgtttgactc aactcaactc ctttaacgct aatatttccg gcaaaatccc   1080

atgcttgggt tttgtcttta accttgtaac gcttgcaatc ccaataaagc attaaaagtc   1140

atgatcttc                                                           1149


<210>  7681
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7681

Met Ser Ile Asp Leu Phe Pro Leu Phe Val Ser Trp Gly Ile Phe Pro 
1               5                   10                  15


Phe Phe Phe Phe Phe Val Phe Phe Leu Pro Leu Leu Ser Phe Met Arg 
            20                  25                  30


Ser Glu Thr Lys Leu Asn Pro Pro Pro Met 
        35                  40


<210>  7682
<211>  1574
<212>  DNA
<213>  Homo sapiens

<400>  7682
ggctgggcgg ggggagttct ggggtaggaa gtggtcccgg gagattttgg atggaaaagt     60

caggaggatt gacagcagac ttgcagaatt acatagagaa attaggaacc cccaaatttc    120

atgtcaattg atctattccc cctctttgtt tcttggggca tttttccttt tttttttttt    180

tttgtttttt ttttacccct ccttagcttt atgcgctcag aaaccaaatt aaaccccccc    240

cccatgtaac aggggggcag tgacaaaagc aagaacgcac gaagccagcc tggagaccac    300

cacgtcctgc cccccgccat ttatcgccct gattggattt tgtttttcat ctgtccctgt    360

tgcttgggtt gagttgaggg tggagcctcc tggggggcac tggccactga gcccccttgg    420

agaagtcaga ggggagtgga gaaggccact gtccggcctg gcttctgggg acagtggctg    480

gtccccagaa gtcctgaggg cggagggggg ggttgggcag ggtctcctca ggtgtcagga    540

gggtgctcgg aggccacagg agggggctcc tggctggcct gaggctggcc ggaggggaag    600

gggctagcag gtgtgtaaac agagggttcc atcaggctgg ggcagggtgg ccgccttccg    660

cacacttgag gaaccctccc ctctccctcg gtgacatctt gcccgcccct cagcaccctg    720

ccttgtctcc aggaggtccg aagctctgtg ggacctcttg ggggcaaggt ggggtgaggc    780

cggggagtag ggaggtcagg cgggtctgag cccacagagc aggagagctg ccaggtctgc    840

ccatcgacca ggttgcttgg gccccggagc ccacgggtct ggtgatgcca tagcagccac    900

caccgcgccc gactagcagt ctagaggcct gaggcttctg ggtcctggtg acggggctgg    960

catgaccccg ggggtcgtcc atgccagtcc gcctcagtcg cagagggtcc ctcggcaagc   1020

gccctgtgag tgggccattc ggaacattgg acagaagccc aaagagccaa attgtcacaa   1080

ttgtggaacc cacattggcc tgagatccaa aacgcttcga ggcaccccaa attacctgcc   1140

cattcgtcag gacacccacc cacccagtgt tatattctgc ctcgccggag tgggtgttcc   1200

cgggggcact tgccgaccag ccccttgcgt ccccaggttt gcagctctcc cctgggccac   1260

taaccatcct ggcccgggct gcctgtctga cctccgtgcc tagtcgtggc tctccatctt   1320

gtctcctccc cgtgtcccca atgtcttcag tggggggccc cctcttgggt cccctcctct   1380

gccatcacct gaagaccccc acgccaaaca ctgaatgtca cctgtgcctg ccgcctcggt   1440

ccaccttgcg gcccgtgttt gactcaactc aactccttta acgctaatat ttccggcaaa   1500

atcccatgct tgggttttgt ctttaacctt gtaacgcttg caatcccaat aaagcattaa   1560

aagtcatgat cttc                                                     1574


<210>  7683
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7683

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7684
<211>  1467
<212>  DNA
<213>  Homo sapiens

<400>  7684
gtgggtgggg ggcagtgggg gctgggcggg gggagttctg gggtaggaag tggtcccggg     60

agattttgga tggaaaagtc aggaggattg acagcagact tgcagaatta catagagaaa    120

ttaggaaccc ccaaatttca tgtcaattga tctattcccc ctctttgttt cttggggcat    180

ttttcctttt tttttttttt ttgttttttt tttacccctc cttagcttta tgcgctcaga    240

aaccaaatta aacccccccc ccatgtaaca ggggggcagt gacaaaagca agaacgcacg    300

aagccagcct ggagaccacc acgtcctgcc ccccgccatt tatcgccctg attggatttt    360

gtttttcatc tgtccctgtt gcttgggttg agttgagggt ggagcctcct ggggggcact    420

ggccactgag cccccttgga gaagtcagag gggagtggag aaggccactg tccggcctgg    480

cttctgggga cagtggctgg tccccagaag tcctgagggc ggaggggggg gttgggcagg    540

gtctcctcag gtgtcaggag ggtgctcgga ggccacagga gggggctcct ggctggcctg    600

aggctggccg gaggggaagg ggctagcagg tgtgtaaaca gagggttcca tcaggcaggt    660

tgcttgggcc ccggagccca cgggtctggt gatgccatag cagccaccac cgcggcgcct    720

agggctgcgg cagggactcg gcctctggga ggtttacctc gcccccactt gtgcccccag    780

ctcagccccc ctgcacgcag cccgactagc agtctagagg cctgaggctt ctgggtcctg    840

gtgacggggc tggcatgacc ccgggggtcg tccatgccag tccgcctcag tcgcagaggg    900

tccctcggca agcgccctgt gagtgggcca ttcggaacat tggacagaag cccaaagagc    960

caaattgtca caattgtgga acccacattg gcctgagatc caaaacgctt cgaggcaccc   1020

caaattacct gcccattcgt caggacaccc acccacccag tgttatattc tgcctcgccg   1080

gagtgggtgt tcccgggggc acttgccgac cagccccttg cgtccccagg tttgcagctc   1140

tcccctgggc cactaaccat cctggcccgg gctgcctgtc tgacctccgt gcctagtcgt   1200

ggctctccat cttgtctcct ccccgtgtcc ccaatgtctt cagtgggggg ccccctcttg   1260

ggtcccctcc tctgccatca cctgaagacc cccacgccaa acactgaatg tcacctgtgc   1320

ctgccgcctc ggtccacctt gcggcccgtg tttgactcaa ctcaactcct ttaacgctaa   1380

tatttccggc aaaatcccat gcttgggttt tgtctttaac cttgtaacgc ttgcaatccc   1440

aataaagcat taaaagtcat gatcttc                                       1467


<210>  7685
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7685

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7686
<211>  1231
<212>  DNA
<213>  Homo sapiens

<400>  7686
gtgggtgggg ggcagtgggg gctgggcggg gggagttctg gggtaggaag tggtcccggg     60

agattttgga tggaaaagtc aggaggattg acagcagact tgcagaatta catagagaaa    120

ttaggaaccc ccaaatttca tgtcaattga tctattcccc ctctttgttt cttggggcat    180

ttttcctttt tttttttttt ttgttttttt tttacccctc cttagcttta tgcgctcaga    240

aaccaaatta aacccccccc ccatgtaaca ggggggcagt gacaaaagca agaacgcacg    300

aagccagcct ggagaccacc acgtcctgcc ccccgccatt tatcgccctg attggatttt    360

gtttttcatc tgtccctgtt gcttgggttg agttgagggt ggagcctcct ggggggcact    420

ggccactgag cccccttgga gaagtcagag gggagtggag aaggccactg tccggcctgg    480

cttctgggga cagtggctgg tccccagaag tcctgagggc ggaggggggg gttgggcagg    540

gtctcctcag gtgtcaggag ggtgctcgga ggccacagga gggggctcct ggctggcctg    600

aggctggccg gaggggaagg ggctagcagg tgtgtaaaca gaggtccgcc tcagtcgcag    660

agggtccctc ggcaagcgcc ctgtgagtgg gccattcgga acattggaca gaagcccaaa    720

gagccaaatt gtcacaattg tggaacccac attggcctga gatccaaaac gcttcgaggc    780

accccaaatt acctgcccat tcgtcaggac acccacccac ccagtgttat attctgcctc    840

gccggagtgg gtgttcccgg gggcacttgc cgaccagccc cttgcgtccc caggtttgca    900

gctctcccct gggccactaa ccatcctggc ccgggctgcc tgtctgacct ccgtgcctag    960

tcgtggctct ccatcttgtc tcctccccgt gtccccaatg tcttcagtgg ggggccccct   1020

cttgggtccc ctcctctgcc atcacctgaa gacccccacg ccaaacactg aatgtcacct   1080

gtgcctgccg cctcggtcca ccttgcggcc cgtgtttgac tcaactcaac tcctttaacg   1140

ctaatatttc cggcaaaatc ccatgcttgg gttttgtctt taaccttgta acgcttgcaa   1200

tcccaataaa gcattaaaag tcatgatctt c                                  1231


<210>  7687
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  7687

Met Ser Ser Val Gly Gly Pro Leu Leu Gly Pro Leu Leu Cys His His 
1               5                   10                  15


Leu Lys Thr Pro Thr Pro Asn Thr Glu Cys His Leu Cys Leu Pro Pro 
            20                  25                  30


Arg Ser Thr Leu Arg Pro Val Phe Asp Ser Thr Gln Leu Leu 
        35                  40                  45


<210>  7688
<211>  1524
<212>  DNA
<213>  Homo sapiens

<400>  7688
gtgtgggaag tctggcggtt ggaggggtgg gtggggggca gtgggggctg ggcgggggga     60

gttctggggt aggaagtggt cccgggagat tttggatgga aaagtcagga ggattgacag    120

cagacttgca gaattacata gagaaattag gaacccccaa atttcatgtc aattgatcta    180

ttccccctct ttgtttcttg gggcattttt cctttttttt ttttttttgt ttttttttta    240

cccctcctta gctttatgcg ctcagaaacc aaattaaacc ccccccccat gtaacagggg    300

ggcagtgaca aaagcaagaa cgcacgaagc cagcctggag accaccacgt cctgcccccc    360

gccatttatc gccctgattg gattttgttt ttcatctgtc cctgttgctt gggttgagtt    420

gagggtggag cctcctgggg ggcactggcc actgagcccc cttggagaag tcagagggga    480

gtggagaagg ccactgtccg gcctggcttc tggggacagt ggctggtccc cagaagtccc    540

tcccctctcc ctcggtgaca tcttgcccgc ccctcagcac cctgccttgt ctccaggagg    600

tccgaagctc tgtgggacct cttgggggca aggtggggtg aggccgggga gtagggaggt    660

caggcgggtc tgagcccaca gagcaggaga gctgccaggt ctgcccatcg accaggttgc    720

ttgggccccg gagcccacgg gtctggtgat gccatagcag ccaccaccgc ggcgcctagg    780

gctgcggcag ggactcggcc tctgggaggt ttacctcgcc cccacttgtg cccccagctc    840

agcccccctg cacgcagccc gactagcagt ctagaggcct gaggcttctg ggtcctggtg    900

acggggctgg catgaccccg ggggtcgtcc atgccagtcc gcctcagtcg cagagggtcc    960

ctcggcaagc gccctgtgag tgggccattc ggaacattgg acagaagccc aaagagccaa   1020

attgtcacaa ttgtggaacc cacattggcc tgagatccaa aacgcttcga ggcaccccaa   1080

attacctgcc cattcgtcag gacacccacc cacccagtgt tatattctgc ctcgccggag   1140

tgggtgttcc cgggggcact tgccgaccag ccccttgcgt ccccaggttt gcagctctcc   1200

cctgggccac taaccatcct ggcccgggct gcctgtctga cctccgtgcc tagtcgtggc   1260

tctccatctt gtctcctccc cgtgtcccca atgtcttcag tggggggccc cctcttgggt   1320

cccctcctct gccatcacct gaagaccccc acgccaaaca ctgaatgtca cctgtgcctg   1380

ccgcctcggt ccaccttgcg gcccgtgttt gactcaactc aactccttta acgctaatat   1440

ttccggcaaa atcccatgct tgggttttgt ctttaacctt gtaacgcttg caatcccaat   1500

aaagcattaa aagtcatgat cttc                                          1524


<210>  7689
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7689

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7690
<211>  1598
<212>  DNA
<213>  Homo sapiens

<400>  7690
attcccgata caccttactt actgtgtgtt ggcccagcca gagtgaggaa ggagtttggc     60

cacattggag atggcggtag ctgagcagac atgcccccac gagtagcctg actccctggt    120

gtgctcctgg aaggaagatc ttggggaccc ccccaccgga gcacacctag ggatcatctt    180

tgcccgtctc ctggggaccc cccaagaaat gtggagtcct cgggggccgt gcactgatgc    240

ggggagtgtg ggaagtctgg cggttggagg ggtgggtggg gggcagtggg ggctgggcgg    300

ggggagttct ggggtaggaa gtggtcccgg gagattttgg atggaaaagt caggaggatt    360

gacagcagac ttgcagaatt acatagagaa attaggaacc cccaaatttc atgtcaattg    420

atctattccc cctctttgtt tcttggggca tttttccttt tttttttttt tttgtttttt    480

ttttacccct ccttagcttt atgcgctcag aaaccaaatt aaaccccccc cccatgtaac    540

aggggggcag tgacaaaagc aagaacgcac gaagccagcc tggagaccac cacgtcctgc    600

cccccgccat ttatcgccct gattggattt tgtttttcat ctgtccctgt tgcttgggtt    660

gagttgaggg tggagcctcc tggggggcac tggccactga gcccccttgg agaagtcaga    720

ggggataggg aggtcaggcg ggtctgagcc cacagagcag gagagctgcc aggtctgccc    780

atcgaccagg ttgcttgggc cccggagccc acgggtctgg tgatgccata gcagccacca    840

ccgcggcgcc tagggctgcg gcagggactc ggcctctggg aggtttacct cgcccccact    900

tgtgccccca gctcagcccc cctgcacgca gcccgactag cagtctagag gcctgaggct    960

tctgggtcct ggtgacgggg ctggcatgac cccgggggtc gtccatgcca gtccgcctca   1020

gtcgcagagg gtccctcggc aagcgccctg tgagtgggcc attcggaaca ttggacagaa   1080

gcccaaagag ccaaattgtc acaattgtgg aacccacatt ggcctgagat ccaaaacgct   1140

tcgaggcacc ccaaattacc tgcccattcg tcaggacacc cacccaccca gtgttatatt   1200

ctgcctcgcc ggagtgggtg ttcccggggg cacttgccga ccagcccctt gcgtccccag   1260

gtttgcagct ctcccctggg ccactaacca tcctggcccg ggctgcctgt ctgacctccg   1320

tgcctagtcg tggctctcca tcttgtctcc tccccgtgtc cccaatgtct tcagtggggg   1380

gccccctctt gggtcccctc ctctgccatc acctgaagac ccccacgcca aacactgaat   1440

gtcacctgtg cctgccgcct cggtccacct tgcggcccgt gtttgactca actcaactcc   1500

tttaacgcta atatttccgg caaaatccca tgcttgggtt ttgtctttaa ccttgtaacg   1560

cttgcaatcc caataaagca ttaaaagtca tgatcttc                           1598


<210>  7691
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7691

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7692
<211>  1859
<212>  DNA
<213>  Homo sapiens

<400>  7692
agcgtgagcc acgatgctcc ccatacccca cccattcccg atacacctta cttactgtgt     60

gttggcccag ccagagtgag gaaggagttt ggccacattg gagatggcgg tagctgagca    120

gacatgcccc cacgagtagc ctgactccct ggtgtgctcc tggaaggaag atcttgggga    180

cccccccacc ggagcacacc tagggatcat ctttgcccgt ctcctgggga ccccccaaga    240

aatgtggagt cctcgggggc cgtgcactga tgcggggagt gtgggaagtc tggcggttgg    300

aggggtgggt ggggggcagt gggggctggg cggggggagt tctggggtag gaagtggtcc    360

cgggagattt tggatggaaa agtcaggagg attgacagca gacttgcaga attacataga    420

gaaattagga acccccaaat ttcatgtcaa ttgatctatt ccccctcttt gtttcttggg    480

gcatttttcc tttttttttt ttttttgttt tttttttacc cctccttagc tttatgcgct    540

cagaaaccaa attaaacccc ccccccatgt aacagggggg cagtgacaaa agcaagaacg    600

cacgaagcca gcctggagac caccacgtcc tgccccccgc catttatcgc cctgattgga    660

ttttgttttt catctgtccc tgttgcttgg gttgagttga gggtggagcc tcctgggggg    720

cactggccac tgagccccct tggagaagtc agaggggagt ggagaaggcc actgtccggc    780

ctggcttctg gggacagtgg ctggtcccca gaagtcctga gggcggaggg gggggttggg    840

cagggtctcc tcaggtgtca ggagggtgct cggaggccac aggagggggc tcctggctgg    900

cctgaggctg gccggagggg aaggggctag caggtgtgta aacagagggt tccatcaggc    960

tggggcaggg tggccgcctt ccgcacactt gaggtcaggc gggtctgagc ccacagagca   1020

ggagagctgc caggtctgcc catcgaccag gttgcttggg ccccggagcc cacgggtctg   1080

gtgatgccat agcagccacc accgcggcgc ctagggctgc ggcagggact cggcctctgg   1140

gaggtttacc tcgcccccac ttgtgccccc agctcagccc ccctgcacgc agcccgacta   1200

gcagtctaga ggcctgaggc ttctgggtcc tggtgacggg gctggcatga ccccgggggt   1260

cgtccatgcc agtccgcctc agtcgcagag ggtccctcgg caagcgccct gtgagtgggc   1320

cattcggaac attggacaga agcccaaaga gccaaattgt cacaattgtg gaacccacat   1380

tggcctgaga tccaaaacgc ttcgaggcac cccaaattac ctgcccattc gtcaggacac   1440

ccacccaccc agtgttatat tctgcctcgc cggagtgggt gttcccgggg gcacttgccg   1500

accagcccct tgcgtcccca ggtttgcagc tctcccctgg gccactaacc atcctggccc   1560

gggctgcctg tctgacctcc gtgcctagtc gtggctctcc atcttgtctc ctccccgtgt   1620

ccccaatgtc ttcagtgggg ggccccctct tgggtcccct cctctgccat cacctgaaga   1680

cccccacgcc aaacactgaa tgtcacctgt gcctgccgcc tcggtccacc ttgcggcccg   1740

tgtttgactc aactcaactc ctttaacgct aatatttccg gcaaaatccc atgcttgggt   1800

tttgtcttta accttgtaac gcttgcaatc ccaataaagc attaaaagtc atgatcttc    1859


<210>  7693
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7693

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7694
<211>  1745
<212>  DNA
<213>  Homo sapiens

<400>  7694
gtcccgctaa gattctccaa tgttttcatg gtctgagccc cgctcctgtt cccatctcca     60

ctgcccctcg gccctgtctg tgccctgcct ctcagaggag ggggctcaga tggtgcggcc    120

tgagtgtgcg gccggcggca tttgggatac acccgtaggg tgggcggggt gtgtcccagg    180

cctaattcca tctttccacc atgacagaga tgcccttgtg aggctggcct ccttggcgcc    240

tgtccccacg gcccccgcag cgtgagccac gatgctcccc ataccccacc cattcccgat    300

acaccttact tactgtgtgt tggcccagcc agagtgagga aggagtttgg ccacattgga    360

gatggcggta gctgagcaga catgccccca cgagtagcct gactccctgg tgtgctcctg    420

gaaggaagat cttggggacc cccccaccgg agcacaccta gggatcatct ttgcccgtct    480

cctggggacc ccccaagaaa tgtggagtcc tcgggggccg tgcactgatg cggggagtgt    540

gggaagtctg gcggttggag gggtgggtgg ggggcagtgg gggctgggcg gggggagttc    600

tggggtagga agtggtcccg ggagattttg gatggaaaag tcaggagggg gctcctggct    660

ggcctgaggc tggccggagg ggaaggggct agcaggtgtg taaacagagg gttccatcag    720

gctggggcag ggtggccgcc ttccgcacac ttgaggaacc ctcccctctc cctcggtgac    780

atcttgcccg cccctcagca ccctgccttg tctccaggag gtccgaagct ctgtgggacc    840

tcttgggggc aaggtggggt gaggccgggg agtagggagg tcaggcgggt ctgagcccac    900

agagcaggag agctgccagg tctgcccatc gaccaggttg cttgggcccc ggagcccacg    960

ggtctggtga tgccatagca gccaccaccg cggcgcctag ggctgcggca gggactcggc   1020

ctctgggagg tttacctcgc ccccacttgt gcccccagct cagcccccct gcacgcagcc   1080

cgactagcag tctagaggcc tgaggcttct gggtcctggt gacggggctg gcatgacccc   1140

gggggtcgtc catgccagtc cgcctcagtc gcagagggtc cctcggcaag cgccctgtga   1200

gtgggccatt cggaacattg gacagaagcc caaagagcca aattgtcaca attgtggaac   1260

ccacattggc ctgagatcca aaacgcttcg aggcacccca aattacctgc ccattcgtca   1320

ggacacccac ccacccagtg ttatattctg cctcgccgga gtgggtgttc ccgggggcac   1380

ttgccgacca gccccttgcg tccccaggtt tgcagctctc ccctgggcca ctaaccatcc   1440

tggcccgggc tgcctgtctg acctccgtgc ctagtcgtgg ctctccatct tgtctcctcc   1500

ccgtgtcccc aatgtcttca gtggggggcc ccctcttggg tcccctcctc tgccatcacc   1560

tgaagacccc cacgccaaac actgaatgtc acctgtgcct gccgcctcgg tccaccttgc   1620

ggcccgtgtt tgactcaact caactccttt aacgctaata tttccggcaa aatcccatgc   1680

ttgggttttg tctttaacct tgtaacgctt gcaatcccaa taaagcatta aaagtcatga   1740

tcttc                                                               1745


<210>  7695
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  7695

Met Trp Ser Pro Arg Gly Pro Cys Thr Asp Ala Gly Ser Val Gly Ser 
1               5                   10                  15


Leu Ala Val Gly Gly Val Gly Gly Gly Gln Trp Gly Leu Gly Gly Gly 
            20                  25                  30


Ser Ser Gly Val Gly Ser Gly Pro Gly Arg Phe Trp Met Glu Lys Ser 
        35                  40                  45


Gly Gly Gly Ser Trp Leu Ala 
    50                  55


<210>  7696
<211>  2550
<212>  DNA
<213>  Homo sapiens

<400>  7696
gcacacacga acacagcaca cacagcacac acacaaacac agcacacaca tgcacacagc     60

acacgcacac acagcacaca catgaacaca gcacacagca cacacatgca cacacagcac    120

acacgcatgc acagcacaca tgaacacagc acacacacaa acacacagca cacacatgca    180

cacacagcac acacactcat gcgcagcaca tacatgaaca cagctcacag cacacaaaca    240

cgcagcacac acgttgcaca cgcaagcacc cacctgcaca cacacatgcg cacacacacg    300

cacaccccca caaaattgga tgaaaacaat aagcatatct aagcaactac gatatctgta    360

tggatcaggc caaagtcccg ctaagattct ccaatgtttt catgaggagg gggctcagat    420

ggtgcggcct gagtgtgcgg ccggcggcat ttgggataca cccgtagggt gggcggggtg    480

tgtcccaggc ctaattccat ctttccacca tgacagagat gcccttgtga ggctggcctc    540

cttggcgcct gtccccacgg cccccgcagc gtgagccacg atgctcccca taccccaccc    600

attcccgata caccttactt actgtgtgtt ggcccagcca gagtgaggaa ggagtttggc    660

cacattggag atggcggtag ctgagcagac atgcccccac gagtagcctg actccctggt    720

gtgctcctgg aaggaagatc ttggggaccc ccccaccgga gcacacctag ggatcatctt    780

tgcccgtctc ctggggaccc cccaagaaat gtggagtcct cgggggccgt gcactgatgc    840

ggggagtgtg ggaagtctgg cggttggagg ggtgggtggg gggcagtggg ggctgggcgg    900

ggggagttct ggggtaggaa gtggtcccgg gagattttgg atggaaaagt caggaggatt    960

gacagcagac ttgcagaatt acatagagaa attaggaacc cccaaatttc atgtcaattg   1020

atctattccc cctctttgtt tcttggggca tttttccttt tttttttttt tttgtttttt   1080

ttttacccct ccttagcttt atgcgctcag aaaccaaatt aaaccccccc cccatgtaac   1140

aggggggcag tgacaaaagc aagaacgcac gaagccagcc tggagaccac cacgtcctgc   1200

cccccgccat ttatcgccct gattggattt tgtttttcat ctgtccctgt tgcttgggtt   1260

gagttgaggg tggagcctcc tggggggcac tggccactga gcccccttgg agaagtcaga   1320

ggggagtgga gaaggccact gtccggcctg gcttctgggg acagtggctg gtccccagaa   1380

gtcctgaggg cggagggggg ggttgggcag ggtctcctca ggtgtcagga gggtgctcgg   1440

aggccacagg agggggctcc tggctggcct gaggctggcc ggaggggaag gggctagcag   1500

gtgtgtaaac agagggttcc atcaggctgg ggcagggtgg ccgccttccg cacacttgag   1560

gaaccctccc ctctccctcg gtgacatctt gcccgcccct cagcaccctg ccttgtctcc   1620

aggaggtccg aagctctgtg ggacctcttg ggggcaaggt ggggtgaggc cggggagtag   1680

ggaggtcagg cgggtctgag cccacagagc aggagagctg ccaggtctgc ccatcgacca   1740

ggttgcttgg gccccggagc ccacgggtct ggtgatgcca tagcagccac caccgcggcg   1800

cctagggctg cggcagggac tcggcctctg ggaggtttac ctcgccccca cttgtgcccc   1860

cagctcagcc cccctgcacg cagcccgact agcagtctag aggcctgagg cttctgggtc   1920

ctggtgacgg ggctggcatg accccggggg tcgtccatgc cagtccgcct cagtcgcaga   1980

gggtccctcg gcaagcgccc tgtgagtggg ccattcggaa cattggacag aagcccaaag   2040

agccaaattg tcacaattgt ggaacccaca ttggcctgag atccaaaacg cttcgaggca   2100

ccccaaatta cctgcccatt cgtcaggaca cccacccacc cagtgttata ttctgcctcg   2160

ccggagtggg tgttcccggg ggcacttgcc gaccagcccc ttgcgtcccc aggtttgcag   2220

ctctcccctg ggccactaac catcctggcc cgggctgcct gtctgacctc cgtgcctagt   2280

cgtggctctc catcttgtct cctccccgtg tccccaatgt cttcagtggg gggccccctc   2340

ttgggtcccc tcctctgcca tcacctgaag acccccacgc caaacactga atgtcacctg   2400

tgcctgccgc ctcggtccac cttgcggccc gtgtttgact caactcaact cctttaacgc   2460

taatatttcc ggcaaaatcc catgcttggg ttttgtcttt aaccttgtaa cgcttgcaat   2520

cccaataaag cattaaaagt catgatcttc                                    2550


<210>  7697
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  7697

Met Lys Thr Ile Ser Ile Ser Lys Gln Leu Arg Tyr Leu Tyr Gly Ser 
1               5                   10                  15


Gly Gln Ser Pro Ala Lys Ile Leu Gln Cys Phe His Glu Glu Gly Ala 
            20                  25                  30


Gln Met Val Arg Pro Glu Cys Ala Ala Gly Gly Ile Trp Asp Thr Pro 
        35                  40                  45


Val Gly Trp Ala Gly Cys Val Pro Gly Leu Ile Pro Ser Phe His His 
    50                  55                  60


Asp Arg Asp Ala Leu Val Arg Leu Ala Ser Leu Ala Pro Val Pro Thr 
65                  70                  75                  80


Ala Pro Ala Ala 



<210>  7698
<211>  1700
<212>  DNA
<213>  Homo sapiens

<400>  7698
tccccgcagc tacacacaca caacacacag cacacgcatg aacacagcac acacacgagc     60

acagcacaca cacaaacgca cagcacacac agcacacaga tgagcacaca gcacacacac    120

aaacgcacag cacacacacg cacacacatg cacacacagc acacaaacgc acggcacaca    180

cacgcacaca catgcacaca cagcacacac acaaacgcac agcacacaca aacgcacagc    240

acacacgcac acacagcaca cacacgagca cacagcacac aaacgcacag cacacgcaca    300

cacatgcaca cacagcacac acactagcac acagcacaca cacaaagaca cagcacacac    360

atgcacacac agcacacaca cgcgaacaca gcacacacga acacagcaca cacagcacac    420

acacaaacac agcacacaca tgcacacagc acacgcacac acagcacaca catgaacaca    480

gcacacagca cacacatgca cacacagcac acacgcatgc acagcacaca tgaacacagc    540

acacacacaa acacacagca cacacatgca cacacagcac acacactcat gcgcagcaca    600

tacatgaaca cagctcacag cacacaaaca cgcagcacac acgttgcaca cgcaagcacc    660

cacctgcaca cacacatgcg cacacacacg cacaccccca caaaattgga tgaaaacaat    720

aagcatatct aagcaactac gatatctgta tggatcaggc caaagtcccg ctaagattct    780

ccaatgtttt catggtctga gccccgctcc tgttcccatc tccactgccc ctcggccctg    840

tctgtgccct gcctctcaga ggagggggct cagatggtgc ggcctgagtg tgcggccggc    900

ggcatttggg atacacccgt agggtgggcg gggtgtgtcc caggcctaat tccatctttc    960

caccatgaca gagatgccct tgtgaggctg gcctccttgg cgcctgtccc cacggccccc   1020

gcagcgtgag ccacgatgct ccccataccc cacccattcc cgatacacct tacttactgt   1080

gtgttggccc agccagagtg aggaaggagt ttggccacat tggagatggc ggtagctgag   1140

cagacatgcc cccacgagta gcctgactcc ctggtgtgct cctggaagga agatcttggg   1200

gaccccccca ccggagcaca cctagggatc atctttgccc gtctcctggg gaccccccaa   1260

gaaatgtgga gtcctcgggg gccgtgcact gatgcgggga gtgtgggaag tctggcggtt   1320

ggaggggtgg gtggggggca gtgggggctg ggcgggggga gttctggggt aggaagtggt   1380

cccgggagat tttggatgga aaagtcagga ggattgacag cagacttgca gaattacata   1440

gagaaattag gaacccccaa atttcatgtc aattgatcta ttcccccttc ttgggtcccc   1500

tcctctgcca tcacctgaag acccccacgc caaacactga atgtcacctg tgcctgccgc   1560

ctcggtccac cttgcggccc gtgtttgact caactcaact cctttaacgc taatatttcc   1620

ggcaaaatcc catgcttggg ttttgtcttt aaccttgtaa cgcttgcaat cccaataaag   1680

cattaaaagt catgatcttc                                               1700


<210>  7699
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  7699

Met His Thr Gln His Thr His Ala Asn Thr Ala His Thr Asn Thr Ala 
1               5                   10                  15


His Thr Ala His Thr Gln Thr Gln His Thr His Ala His Ser Thr Arg 
            20                  25                  30


Thr His Ser Thr His Met Asn Thr Ala His Ser Thr His Met His Thr 
        35                  40                  45


Gln His Thr Arg Met His Ser Thr His Glu His Ser Thr His Thr Asn 
    50                  55                  60


Thr Gln His Thr His Ala His Thr Ala His Thr Leu Met Arg Ser Thr 
65                  70                  75                  80


Tyr Met Asn Thr Ala His Ser Thr Gln Thr Arg Ser Thr His Val Ala 
                85                  90                  95


His Ala Ser Thr His Leu His Thr His Met Arg Thr His Thr His Thr 
            100                 105                 110


Pro Thr Lys Leu Asp Glu Asn Asn Lys His Ile 
        115                 120


<210>  7700
<211>  1473
<212>  DNA
<213>  Homo sapiens

<400>  7700
ccatcactaa aaatcacaga gcagtcagag ggacccagta agaccaaagg aggggaggac     60

agagcatgaa aaccaaaatc catgcaaatg aaatgtaatt ggcacgaccc tcacccccaa    120

atcttacatc tcaattccca tcctaaaaag cactcatact ttatgcatcc ccgcagctac    180

acacacacaa cacacagcac acgcatgaac acagcacaca cacgagcaca gcacacacac    240

aaacgcacag cacacacagc acacagatga gcacacagca cacacacaaa cgcacagcac    300

acacacgcac acacatgcac acacagcaca caaacgcacg gcacacacac gcacacacat    360

gcacacacag cacacacaca aacgcacagc acacacaaac gcacagcaca cacgcacaca    420

cagcacacac acgagcacac agcacacaaa cgcacagcac acgcacacac atgcacacac    480

agcacacaca ctagcacaca gcacacacac aaagacacag cacacacatg cacacacagc    540

acacacacgc gaacacagca cacacgaaca cagcacacac agcacacaca caaacacagc    600

acacacatgc acacagcaca cgcacacaca gcacacacat gaacacagca cacagcacac    660

acatgcacac acagcacaca cgcatgcaca gcacacatga acacagcaca cacacaaaca    720

cacagcacac acatgcacac acagcacaca cactcatgcg cagcacatac atgaacacag    780

ctcacactca gcccccctgc acgcagcccg actagcagtc tagaggcctg aggcttctgg    840

gtcctggtga cggggctggc atgaccccgg gggtcgtcca tgccagtccg cctcagtcgc    900

agagggtccc tcggcaagcg ccctgtgagt gggccattcg gaacattgga cagaagccca    960

aagagccaaa ttgtcacaat tgtggaaccc acattggcct gagatccaaa acgcttcgag   1020

gcaccccaaa ttacctgccc attcgtcagg acacccaccc acccagtgtt atattctgcc   1080

tcgccggagt gggtgttccc gggggcactt gccgaccagc cccttgcgtc cccaggtttg   1140

cagctctccc ctgggccact aaccatcctg gcccgggctg cctgtctgac ctccgtgcct   1200

agtcgtggct ctccatcttg tctcctcccc gtgtccccaa tgtcttcagt ggggggcccc   1260

ctcttgggtc ccctcctctg ccatcacctg aagaccccca cgccaaacac tgaatgtcac   1320

ctgtgcctgc cgcctcggtc caccttgcgg cccgtgtttg actcaactca actcctttaa   1380

cgctaatatt tccggcaaaa tcccatgctt gggttttgtc tttaaccttg taacgcttgc   1440

aatcccaata aagcattaaa agtcatgatc ttc                                1473


<210>  7701
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  7701

Met His Thr Gln His Thr His Ala Asn Thr Ala His Thr Asn Thr Ala 
1               5                   10                  15


His Thr Ala His Thr Gln Thr Gln His Thr His Ala His Ser Thr Arg 
            20                  25                  30


Thr His Ser Thr His Met Asn Thr Ala His Ser Thr His Met His Thr 
        35                  40                  45


Gln His Thr Arg Met His Ser Thr His Glu His Ser Thr His Thr Asn 
    50                  55                  60


Thr Gln His Thr His Ala His Thr Ala His Thr Leu Met Arg Ser Thr 
65                  70                  75                  80


Tyr Met Asn Thr Ala His Thr Gln Pro Pro Cys Thr Gln Pro Asp 
                85                  90                  95


<210>  7702
<211>  954
<212>  DNA
<213>  Homo sapiens

<400>  7702
ccacccaaga ccccgcccac gggggcgccc ccccagagat ggccagcaat cggaagtgag     60

caaaactgcc gcaagtctgc agcccggcgc caccatcctg cagcctcctc ctgaccacgg    120

acgtttccat caggttccat cccgaaaatc tctcggttcc acgtccccct ggggcttctc    180

ctgacccagt ccccgtgccc cgcctccccg aaacaggcta ctctcctcgg ccccctccat    240

cgggctgagg aagcacagca gcatcttcaa acatgtacaa aatcgattgg ctttaaacac    300

ccttcacata ccctcccccc aaattatccc caattatccc cacacataaa aaatcaaaac    360

attaaactaa cccccttccc ccccccccac aacaaccctc ttaaaactaa ttggcttttt    420

agaaacaccc cacaaaagct cagaaattgg ctttaaaaaa aacaaccacc aaaaaaaatc    480

aattggctaa aaaaaaaaag tattaaaaac gaattggctg agaaacaatt ggcaaaataa    540

aggaatttgg cactccccac ccccctcttt ctcttctccc ttggactttg agtcaaattg    600

gcctggactt gagtccctga accagcaaag agaaaagaag gaccccagaa atcacaggtg    660

ggcacgtcgc tgctaccgcc atctcccttc tcacgggaat tttcagggta aactggccat    720

ccgaaaatag caacaaccca gactggctcc tcactcctct gccatcacct gaagaccccc    780

acgccaaaca ctgaatgtca cctgtgcctg ccgcctcggt ccaccttgcg gcccgtgttt    840

gactcaactc aactccttta acgctaatat ttccggcaaa atcccatgct tgggttttgt    900

ctttaacctt gtaacgcttg caatcccaat aaagcattaa aagtcatgat cttc          954


<210>  7703
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  7703

Thr Ser Lys Glu Lys Arg Arg Thr Pro Glu Ile Thr Gly Gly His Val 
1               5                   10                  15


Ala Ala Thr Ala Ile Ser Leu Leu Thr Gly Ile Phe Arg Val Asn Trp 
            20                  25                  30


Pro Ser Glu Asn Ser Asn Asn Pro Asp Trp Leu Leu Thr Pro Leu Pro 
        35                  40                  45


Ser Pro Glu Asp Pro His Ala Lys His 
    50                  55


<210>  7704
<211>  4023
<212>  DNA
<213>  Homo sapiens

<400>  7704
gacaacttcc ccagataccc cgtgggcaag ttcttccaat atgacacctg gaagcagtcc     60

acccagcgcc tgcgcagggg cctgcctgcc ctcctgcgtg cccgccgggg tcacgtgctc    120

gccaaggagc tcgaggcgtt cagggaggcc aaacgtcacc gtcccctgat tgctctaccc    180

acccaagacc ccgcccacgg gggcgccccc ccagagatgg ccagcaatcg gaagtgagca    240

aaactgccgc aagtctgcag cccggcgcca ccatcctgca gcctcctcct gaccacggac    300

gtttccatca ggttccatcc cgaaaatctc tcggttccac gtccccctgg ggcttctcct    360

gacccagtcc ccgtgccccg cctccccgaa acaggctact ctcctcggcc ccctccatcg    420

ggctgaggaa gcacagcagc atcttcaaac atgtacaaaa tcgattggct ttaaacaccc    480

ttcacatacc ctccccccaa attatcccca attatcccca cacataaaaa atcaaaacat    540

taaactaacc cccttccccc ccccccacaa caaccctctt aaaactaatt ggctttttag    600

aaacacccca caaaagctca gaaattggct ttaaaaaaaa caaccaccaa aaaaaatcaa    660

ttggctaaaa aaaaaaagta ttaaaaacga attggctgag aaacaattgg caaaataaag    720

gaatttggca ctccccaccc ccctctttct cttctccctt ggactttgag tcaaattggc    780

ctggacttga gtccctgaac cagcaaagag aaaagaagga ccccagaaat cacaggtggg    840

cacgtcgctg ctaccgccat ctcccttctc acgggaattt tcagggtaaa ctggccatcc    900

gaaaatagca acaacccaga ctggctcctc actccctttt ccatcactaa aaatcacaga    960

gcagtcagag ggacccagta agaccaaagg aggggaggac agagcatgaa aaccaaaatc   1020

catgcaaatg aaatgtaatt ggcacgaccc tcacccccaa atcttacatc tcaattccca   1080

tcctaaaaag cactcatact ttatgcatcc ccgcagctac acacacacaa cacacagcac   1140

acgcatgaac acagcacaca cacgagcaca gcacacacac aaacgcacag cacacacagc   1200

acacagatga gcacacagca cacacacaaa cgcacagcac acacaacaaa cgcacagcac   1260

acacgcacac acagcacaca cacgagcaca cagcacacaa acgcacagca cacgcacaca   1320

catgcacaca cagcacacac actagcacac agcacacaca caaagacaca gcacacacat   1380

gcacacacag cacacacacg cgaacacagc acacacgaac acagcacaca cagcacacac   1440

acaaacacag cacacacatg cacacagcac acgcacacac agcacacaca tgaacacagc   1500

acacagcaca cacatgcaca cacagcacac acgcatgcac agcacacatg aacacagcac   1560

acacacaaac acacagcaca cacatgcaca cacagcacac acactcatgc gcagcacata   1620

catgaacaca gctcacagca cacaaacacg cagcacacac gttgcacacg caagcaccca   1680

cctgcacaca cacatgcgca cacacacgca cacccccaca aaattggatg aaaacaataa   1740

gcatatctaa gcaactacga tatctgtatg gatcaggcca aagtcccgct aagattctcc   1800

aatgttttca tggtctgagc cccgctcctg ttcccatctc cactgcccct cggccctgtc   1860

tgtgccctgc ctctcagagg agggggctca gatggtgcgg cctgagtgtg cggccggcgg   1920

catttgggat acacccgtag ggtgggcggg gtgtgtccca ggcctaattc catctttcca   1980

ccatgacaga gatgcccttg tgaggctggc ctccttggcg cctgtcccca cggcccccgc   2040

agcgtgagcc acgatgctcc ccatacccca cccattcccg atacacctta cttactgtgt   2100

gttggcccag ccagagtgag gaaggagttt ggccacattg gagatggcgg tagctgagca   2160

gacatgcccc cacgagtagc ctgactccct ggtgtgctcc tggaaggaag atcttgggga   2220

cccccccacc ggagcacacc tagggatcat ctttgcccgt ctcctgggga ccccccaaga   2280

aatgtggagt cctcgggggc cgtgcactga tgcggggagt gtgggaagtc tggcggttgg   2340

aggggtgggt ggggggcagt gggggctggg cggggggagt tctggggtag gaagtggtcc   2400

cgggagattt tggatggaaa agtcaggagg attgacagca gacttgcaga attacataga   2460

gaaattagga acccccaaat ttcatgtcaa ttgatctatt ccccctcttt gtttcttggg   2520

gcatttttcc tttttttttt ttttttgttt tttttttacc cctccttagc tttatgcgct   2580

cagaaaccaa attaaacccc ccccccatgt aacagggggg cagtgacaaa agcaagaacg   2640

cacgaagcca gcctggagac caccacgtcc tgccccccgc catttatcgc cctgattgga   2700

ttttgttttt catctgtccc tgttgcttgg gttgagttga gggtggagcc tcctgggggg   2760

cactggccac tgagccccct tggagaagtc agaggggagt ggagaaggcc actgtccggc   2820

ctggcttctg gggacagtgg ctggtcccca gaagtcctga gggcggaggg gggggttggg   2880

cagggtctcc tcaggtgtca ggagggtgct cggaggccac aggagggggc tcctggctgg   2940

cctgaggctg gccggagggg aaggggctag caggtgtgta aacagagggt tccatcaggc   3000

tggggcaggg tggccgcctt ccgcacactt gaggaaccct cccctctccc tcggtgacat   3060

cttgcccgcc cctcagcacc ctgccttgtc tccaggaggt ccgaagctct gtgggacctc   3120

ttgggggcaa ggtggggtga ggccggggag tagggaggtc aggcgggtct gagcccacag   3180

agcaggagag ctgccaggtc tgcccatcga ccaggttgct tgggccccgg agcccacggg   3240

tctggtgatg ccatagcagc caccaccgcg gcgcctaggg ctgcggcagg gactcggcct   3300

ctgggaggtt tacctcgccc ccacttgtgc ccccagctca gcccccctgc acgcagcccg   3360

actagcagtc tagaggcctg aggcttctgg gtcctggtga cggggctggc atgaccccgg   3420

gggtcgtcca tgccagtccg cctcagtcgc agagggtccc tcggcaagcg ccctgtgagt   3480

gggccattcg gaacattgga cagaagccca aagagccaaa ttgtcacaat tgtggaaccc   3540

acattggcct gagatccaaa acgcttcgag gcaccccaaa ttacctgccc attcgtcagg   3600

acacccaccc acccagtgtt atattctgcc tcgccggagt gggtgttccc gggggcactt   3660

gccgaccagc cccttgcgtc cccaggtttg cagctctccc ctgggccact aaccatcctg   3720

gcccgggctg cctgtctgac ctccgtgcct agtcgtggct ctccatcttg tctcctcccc   3780

gtgtccccaa tgtcttcagt ggggggcccc ctcttgggtc ccctcctctg ccatcacctg   3840

aagaccccca cgccaaacac tgaatgtcac ctgtgcctgc cgcctcggtc caccttgcgg   3900

cccgtgtttg actcaactca actcctttaa cgctaatatt tccggcaaaa tcccatgctt   3960

gggttttgtc tttaaccttg taacgcttgc aatcccaata aagcattaaa agtcatgatc   4020

ttc                                                                 4023


<210>  7705
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  7705

Met Ser Thr Gln His Thr His Lys Arg Thr Ala His Thr Thr Asn Ala 
1               5                   10                  15


Gln His Thr Arg Thr His Ser Thr His Thr Ser Thr Gln His Thr Asn 
            20                  25                  30


Ala Gln His Thr His Thr His Ala His Thr Ala His Thr Leu Ala His 
        35                  40                  45


Ser Thr His Thr Lys Thr Gln His Thr His Ala His Thr Ala His Thr 
    50                  55                  60


Arg Glu His Ser Thr His Glu His Ser Thr His Ser Thr His Thr Asn 
65                  70                  75                  80


Thr Ala His Thr Cys Thr Gln His Thr His Thr Gln His Thr His Glu 
                85                  90                  95


His Ser Thr Gln His Thr His Ala His Thr Ala His Thr His Ala Gln 
            100                 105                 110


His Thr 



<210>  7706
<211>  4357
<212>  DNA
<213>  Homo sapiens

<400>  7706
ggcatcgttg aggagtgctg tttccgcagc tgtgacctgg ccctcctgga gacgtactgt     60

gctacccccg ccaagtccga gagggacgtg tcgacccctc cgaccgtgct tccggtgagg    120

gtcctgggcc cctttcccac tctctagaga cagagaaata gggcttcggg cgcccagcgt    180

ttcctgtggc ctctgggacc tcttggccag ggacaaggac ccgtgacttc cttgcttgct    240

gtgtggcccg ggagcagctc agacgctggc tccttctgtc cctctgcccg tggacattag    300

ctcaagtcac tgatcagtca caggggtggc ctgtcaggtc aggcgggcgg ctcaggcgga    360

agagcgtgga gagcaggcac ctgctgacca gccccttccc ctcccaggac aacttcccca    420

gataccccgt gggcaagttc ttccaatatg acacctggaa gcagtccacc cagcgcctgc    480

gcaggggcct gcctgccctc ctgcgtgccc gccggggtca cgtgctcgcc aaggagctcg    540

aggcgttcag ggaggccaaa cgtcaccgtc ccctgattgc tctacccacc caagaccccg    600

cccacggggg cgccccccca gagatggcca gcaatcggaa gtgagcaaaa ctgccgcaag    660

tctgcagccc ggcgccacca tcctgcagcc tcctcctgac cacggacgtt tccatcaggt    720

tccatcccga aaatctctcg gttccacgtc cccctggggc ttctcctgac ccagtccccg    780

tgccccgcct ccccgaaaca ggctactctc ctcggccccc tccatcgggc tgaggaagca    840

cagcagcatc ttcaaacatg tacaaaatcg attggcttta aacaccaacc accaaaaaaa    900

atcaattggc taaaaaaaaa aagtattaaa aacgaattgg ctgagaaaca attggcaaaa    960

taaaggaatt tggcactccc cacccccctc tttctcttct cccttggact ttgagtcaaa   1020

ttggcctgga cttgagtccc tgaaccagca aagagaaaag aaggacccca gaaatcacag   1080

gtgggcacgt cgctgctacc gccatctccc ttctcacggg aattttcagg gtaaactggc   1140

catccgaaaa tagcaacaac ccagactggc tcctcactcc cttttccatc actaaaaatc   1200

acagagcagt cagagggacc cagtaagacc aaaggagggg aggacagagc atgaaaacca   1260

aaatccatgc aaatgaaatg taattggcac gaccctcacc cccaaatctt acatctcaat   1320

tcccatccta aaaagcactc atactttatg catccccgca gctacacaca cacaacacac   1380

agcacacgca tgaacacagc acacacacga gcacagcaca cacacaaacg cacagcacac   1440

acagcacaca gatgagcaca cagcacacac acaaacgcac agcacacaca cgcacacaca   1500

tgcacacaca gcacacaaac gcacggcaca cacacgcaca cacatgcaca cacagcacac   1560

acacaaacgc acagcacaca caaacgcaca gcacacacgc acacacagca cacacacgag   1620

cacacagcac acaaacgcac agcacacgca cacacatgca cacacagcac acacactagc   1680

acacagcaca cacacaaaga cacagcacac acatgcacac acagcacaca cacgcgaaca   1740

cagcacacac gaacacagca cacacagcac acacacaaac acagcacaca catgcacaca   1800

gcacacgcac acacagcaca cacatgaaca cagcacacag cacacacatg cacacacagc   1860

acacacgcat gcacagcaca catgaacaca gcacacacac aaacacacag cacacacatg   1920

cacacacagc acacacactc atgcgcagca catacatgaa cacagctcac agcacacaaa   1980

cacgcagcac acacgttgca cacgcaagca cccacctgca cacacacatg cgcacacaca   2040

cgcacacccc cacaaaattg gatgaaaaca ataagcatat ctaagcaact acgatatctg   2100

tatggatcag gccaaagtcc cgctaagatt ctccaatgtt ttcatggtct gagccccgct   2160

cctgttccca tctccactgc ccctcggccc tgtctgtgcc ctgcctctca gaggaggggg   2220

ctcagatggt gcggcctgag tgtgcggccg gcggcatttg ggatacaccc gtagggtggg   2280

cggggtgtgt cccaggccta attccatctt tccaccatga cagagatgcc cttgtgaggc   2340

tggcctcctt ggcgcctgtc cccacggccc ccgcagcgtg agccacgatg ctccccatac   2400

cccacccatt cccgatacac cttacttact gtgtgttggc ccagccagag tgaggaagga   2460

gtttggccac attggagatg gcggtagctg agcagacatg cccccacgag tagcctgact   2520

ccctggtgtg ctcctggaag gaagatcttg gggacccccc caccggagca cacctaggga   2580

tcatctttgc ccgtctcctg gggacccccc aagaaatgtg gagtcctcgg gggccgtgca   2640

ctgatgcggg gagtgtggga agtctggcgg ttggaggggt gggtgggggg cagtgggggc   2700

tgggcggggg gagttctggg gtaggaagtg gtcccgggag attttggatg gaaaagtcag   2760

gaggattgac agcagacttg cagaattaca tagagaaatt aggaaccccc aaatttcatg   2820

tcaattgatc tattccccct ctttgtttct tggggcattt ttcctttttt tttttttttt   2880

gttttttttt tacccctcct tagctttatg cgctcagaaa ccaaattaaa cccccccccc   2940

atgtaacagg ggggcagtga caaaagcaag aacgcacgaa gccagcctgg agaccaccac   3000

gtcctgcccc ccgccattta tcgccctgat tggattttgt ttttcatctg tccctgttgc   3060

ttgggttgag ttgagggtgg agcctcctgg ggggcactgg ccactgagcc cccttggaga   3120

agtcagaggg gagtggagaa ggccactgtc cggcctggct tctggggaca gtggctggtc   3180

cccagaagtc ctgagggcgg aggggggggt tgggcagggt ctcctcaggt gtcaggaggg   3240

tgctcggagg ccacaggagg gggctcctgg ctggcctgag gctggccgga ggggaagggg   3300

ctagcaggtg tgtaaacaga gggttccatc aggctggggc agggtggccg ccttccgcac   3360

acttgaggaa ccctcccctc tccctcggtg acatcttgcc cgcccctcag caccctgcct   3420

tgtctccagg aggtccgaag ctctgtggga cctcttgggg gcaaggtggg gtgaggccgg   3480

ggagtaggga ggtcaggcgg gtctgagccc acagagcagg agagctgcca ggtctgccca   3540

tcgaccaggt tgcttgggcc ccggagccca cgggtctggt gatgccatag cagccaccac   3600

cgcggcgcct agggctgcgg cagggactcg gcctctggga ggtttacctc gcccccactt   3660

gtgcccccag ctcagccccc ctgcacgcag cccgactagc agtctagagg cctgaggctt   3720

ctgggtcctg gtgacggggc tggcatgacc ccgggggtcg tccatgccag tccgcctcag   3780

tcgcagaggg tccctcggca agcgccctgt gagtgggcca ttcggaacat tggacagaag   3840

cccaaagagc caaattgtca caattgtgga acccacattg gcctgagatc caaaacgctt   3900

cgaggcaccc caaattacct gcccattcgt caggacaccc acccacccag tgttatattc   3960

tgcctcgccg gagtgggtgt tcccgggggc acttgccgac cagccccttg cgtccccagg   4020

tttgcagctc tcccctgggc cactaaccat cctggcccgg gctgcctgtc tgacctccgt   4080

gcctagtcgt ggctctccat cttgtctcct ccccgtgtcc ccaatgtctt cagtgggggg   4140

ccccctcttg ggtcccctcc tctgccatca cctgaagacc cccacgccaa acactgaatg   4200

tcacctgtgc ctgccgcctc ggtccacctt gcggcccgtg tttgactcaa ctcaactcct   4260

ttaacgctaa tatttccggc aaaatcccat gcttgggttt tgtctttaac cttgtaacgc   4320

ttgcaatccc aataaagcat taaaagtcat gatcttc                            4357


<210>  7707
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  7707

Met His Thr Gln His Thr His Ala Asn Thr Ala His Thr Asn Thr Ala 
1               5                   10                  15


His Thr Ala His Thr Gln Thr Gln His Thr His Ala His Ser Thr Arg 
            20                  25                  30


Thr His Ser Thr His Met Asn Thr Ala His Ser Thr His Met His Thr 
        35                  40                  45


Gln His Thr Arg Met His Ser Thr His Glu His Ser Thr His Thr Asn 
    50                  55                  60


Thr Gln His Thr His Ala His Thr Ala His Thr Leu Met Arg Ser Thr 
65                  70                  75                  80


Tyr Met Asn Thr Ala His Ser Thr Gln Thr Arg Ser Thr His Val Ala 
                85                  90                  95


His Ala Ser Thr His Leu His Thr His Met Arg Thr His Thr His Thr 
            100                 105                 110


Pro Thr Lys Leu Asp Glu Asn Asn Lys His Ile 
        115                 120


<210>  7708
<211>  4475
<212>  DNA
<213>  Homo sapiens

<400>  7708
aactggacat tagcttctcc tgtgaaagag acttccagct tcctcctcct cctcttcctc     60

ctcctcctcc tgccccagcg agccttctgc tgagctacac caatgggaat cccaatgggg    120

aagtcgatgc tggtgcttct caccttcttg gccttcgcct cgtgctgcat tgctgcttac    180

cgccccagtg agaccctgtg cggcggggag ctggtggaca ccctccagtt cgtctgtggg    240

gaccgcggct tctacttcag caggcccgca agccgtgtga gccgtcgcag ccgtggcatc    300

gttgaggagt gctgtttccg cagctgtgac ctggccctcc tggagacgta ctgtgctacc    360

cccgacaact tccccagata ccccgtgggc aagttcttcc aatatgacac ctggaagcag    420

tccacccagc gcctgcgcag gggcctgcct gccctcctgc gtgcccgccg gggtcacgtg    480

ctcgccaagg agctcgaggc gttcagggag gccaaacgtc accgtcccct gattgctcta    540

cccacccaag accccgccca cgggggcgcc cccccagaga tggccagcaa tcggaagtga    600

gcaaaactgc cgcaagtctg cagcccggcg ccaccatcct gcagcctcct cctgaccacg    660

gacgtttcca tcaggttcca tcccgaaaat ctctcggttc cacgtccccc tggggcttct    720

cctgacccag tccccgtgcc ccgcctcccc gaaacaggct actctcctcg gccccctcca    780

tcgggctgag gaagcacagc agcatcttca aacatgtaca aaatcgattg gctttaaaca    840

cccttcacat accctccccc caaattatcc ccaattatcc ccacacataa aaaatcaaaa    900

cattaaacta acccccttcc ccccccccca caacaaccct cttaaaacta attggctttt    960

tagaaacacc ccacaaaagc tcagaaattg gctttaaaaa aaacaaccac caaaaaaaat   1020

caattggcta aaaaaaaaaa gtattaaaaa cgaattggct gagaaacaat tggcaaaata   1080

aaggaatttg gcactcccca cccccctctt tctcttctcc cttggacttt gagtcaaatt   1140

ggcctggact tgagtccctg aaccagcaaa gagaaaagaa ggaccccaga aatcacaggt   1200

gggcacgtcg ctgctaccgc catctccctt ctcacgggaa ttttcagggt aaactggcca   1260

tccgaaaata gcaacaaccc agactggctc ctcactccct tttccatcac taaaaatcac   1320

agagcagtca gagggaccca gtaagaccaa aggaggggag gacagagcat gaaaaccaaa   1380

atccatgcaa atgaaatgta attggcacga ccctcacccc caaatcttac atctcaattc   1440

ccatcctaaa aagcactcat actttatgca tccccgcagc tacacacaca caacacacag   1500

cacacgcatg aacacagcac acacacgagc acagcacaca cacaaacgca cagcacacac   1560

agcacacaga tgagcacaca gcacacacac aaacgcacag cacacacacg cacacacatg   1620

cacacacagc acacaaacgc acggcacaca cacgcacaca catgcacaca cagcacacac   1680

acaaacgcac agcacacaca aacgcacagc acacacgcac acacagcaca cacacgagca   1740

cacagcacac aaacgcacag cacacgcaca cacatgcaca cacagcacac acactagcac   1800

acagcacaca cacaaagaca cagcacacac atgcacacac agcacacaca cgcgaacaca   1860

gcacacacga acacagcaca cacagcacac acacaaacac agcacacaca tgcacacagc   1920

acacgcacac acagcacaca catgaacaca gcacacagca cacacatgca cacacagcac   1980

acacgcatgc acagcacaca tgaacacagc acacacacaa acacacagca cacacatgca   2040

cacacagcac acacactcat gcgcagcaca tacatgaaca cagctcacag cacacaaaca   2100

cgcagcacac acgttgcaca cgcaagcacc cacctgcaca cacacatgcg cacacacacg   2160

cacaccccca caaaattgga tgaaaacaat aagcatatct aagcaactac gatatctgta   2220

tggatcaggc caaagtcccg ctaagattct ccaatgtttt catggtctga gccccgctcc   2280

tgttcccatc tccactgccc ctcggccctg tctgtgccct gcctctcaga ggagggggct   2340

cagatggtgc ggcctgagtg tgcggccggc ggcatttggg atacacccgt agggtgggcg   2400

gggtgtgtcc caggcctaat tccatctttc caccatgaca gagatgccct tgtgaggctg   2460

gcctccttgg cgcctgtccc cacggccccc gcagcgtgag ccacgatgct ccccataccc   2520

cacccattcc cgatacacct tacttactgt gtgttggccc agccagagtg aggaaggagt   2580

ttggccacat tggagatggc ggtagctgag cagacatgcc cccacgagta gcctgactcc   2640

ctggtgtgct cctggaagga agatcttggg gaccccccca ccggagcaca cctagggatc   2700

atctttgccc gtctcctggg gaccccccaa gaaatgtgga gtcctcgggg gccgtgcact   2760

gatgcgggga gtgtgggaag tctggcggtt ggaggggtgg gtggggggca gtgggggctg   2820

ggcgggggga gttctggggt aggaagtggt cccgggagat tttggatgga aaagtcagga   2880

ggattgacag cagacttgca gaattacata gagaaattag gaacccccaa atttcatgtc   2940

aattgatcta ttccccctct ttgtttcttg gggcattttt cctttttttt ttttttttgt   3000

ttttttttta cccctcctta gctttatgcg ctcagaaacc aaattaaacc ccccccccat   3060

gtaacagggg ggcagtgaca aaagcaagaa cgcacgaagc cagcctggag accaccacgt   3120

cctgcccccc gccatttatc gccctgattg gattttgttt ttcatctgtc cctgttgctt   3180

gggttgagtt gagggtggag cctcctgggg ggcactggcc actgagcccc cttggagaag   3240

tcagagggga gtggagaagg ccactgtccg gcctggcttc tggggacagt ggctggtccc   3300

cagaagtcct gagggcggag gggggggttg ggcagggtct cctcaggtgt caggagggtg   3360

ctcggaggcc acaggagggg gctcctggct ggcctgaggc tggccggagg ggaaggggct   3420

agcaggtgtg taaacagagg gttccatcag gctggggcag ggtggccgcc ttccgcacac   3480

ttgaggaacc ctcccctctc cctcggtgac atcttgcccg cccctcagca ccctgccttg   3540

tctccaggag gtccgaagct ctgtgggacc tcttgggggc aaggtggggt gaggccgggg   3600

agtagggagg tcaggcgggt ctgagcccac agagcaggag agctgccagg tctgcccatc   3660

gaccaggttg cttgggcccc ggagcccacg ggtctggtga tgccatagca gccaccaccg   3720

cggcgcctag ggctgcggca gggactcggc ctctgggagg tttacctcgc ccccacttgt   3780

gcccccagct cagcccccct gcacgcagcc cgactagcag tctagaggcc tgaggcttct   3840

gggtcctggt gacggggctg gcatgacccc gggggtcgtc catgccagtc cgcctcagtc   3900

gcagagggtc cctcggcaag cgccctgtga gtgggccatt cggaacattg gacagaagcc   3960

caaagagcca aattgtcaca attgtggaac ccacattggc ctgagatcca aaacgcttcg   4020

aggcacccca aattacctgc ccattcgtca ggacacccac ccacccagtg ttatattctg   4080

cctcgccgga gtgggtgttc ccgggggcac ttgccgacca gccccttgcg tccccaggtt   4140

tgcagctctc ccctgggcca ctaaccatcc tggcccgggc tgcctgtctg acctccgtgc   4200

ctagtcgtgg ctctccatct tgtctcctcc ccgtgtcccc aatgtcttca gtggggggcc   4260

ccctcttggg tcccctcctc tgccatcacc tgaagacccc cacgccaaac actgaatgtc   4320

acctgtgcct gccgcctcgg tccaccttgc ggcccgtgtt tgactcaact caactccttt   4380

aacgctaata tttccggcaa aatcccatgc ttgggttttg tctttaacct tgtaacgctt   4440

gcaatcccaa taaagcatta aaagtcatga tcttc                              4475


<210>  7709
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  7709

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly 
                85                  90                  95


Lys Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg 
            100                 105                 110


Arg Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala 
        115                 120                 125


Lys Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile 
    130                 135                 140


Ala Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met 
145                 150                 155                 160


Ala Ser Asn Arg Lys 
                165


<210>  7710
<211>  4538
<212>  DNA
<213>  Homo sapiens

<400>  7710
ggcactgacc agcctgcaaa ctggacatta gcttctcctg tgaaagagac ttccagcttc     60

ctcctcctcc tcttcctcct cctcctcctg ccccagcgag ccttctgctg agctacacca    120

atgggaatcc caatggggaa gtcgatgctg gtgcttctca ccttcttggc cttcgcctcg    180

tgctgcattg ctgcttaccg ccccagtgag accctgtgcg gcggggagct ggtggacacc    240

ctccagttcg tctgtgggga ccgcggcttc tacttcagca ggcccgcaag ccgtgtgagc    300

cgtcgcagcc gtggcatcgt tgaggagtgc tgtttccgca gctgtgacct ggccctcctg    360

gagacgtact gtgctacccc cgccaagtcc gagagggacg tgtcgacccc tccgaccgtg    420

cttccggaca acttccccag ataccccgtg ggcaagttct tccaatatga cacctggaag    480

cagtccaccc agcgcctgcg caggggcctg cctgccctcc tgcgtgcccg ccggggtcac    540

gtgctcgcca aggagctcga ggcgttcagg gaggccaaac gtcaccgtcc cctgattgct    600

ctacccaccc aagaccccgc ccacgggggc gcccccccag agatggccag caatcggaag    660

tgagcaaaac tgccgcaagt ctgcagcccg gcgccaccat cctgcagcct cctcctgacc    720

acggacgttt ccatcaggtt ccatcccgaa aatctctcgg ttccacgtcc ccctggggct    780

tctcctgacc cagtccccgt gccccgcctc cccgaaacag gctactctcc tcggccccct    840

ccatcgggct gaggaagcac agcagcatct tcaaacatgt acaaaatcga ttggctttaa    900

acacccttca cataccctcc ccccaaatta tccccaatta tccccacaca taaaaaatca    960

aaacattaaa ctaaccccct tccccccccc ccacaacaac cctcttaaaa ctaattggct   1020

ttttagaaac accccacaaa agctcagaaa ttggctttaa aaaaaacaac caccaaaaaa   1080

aatcaattgg ctaaaaaaaa aaagtattaa aaacgaattg gctgagaaac aattggcaaa   1140

ataaaggaat ttggcactcc ccacccccct ctttctcttc tcccttggac tttgagtcaa   1200

attggcctgg acttgagtcc ctgaaccagc aaagagaaaa gaaggacccc agaaatcaca   1260

ggtgggcacg tcgctgctac cgccatctcc cttctcacgg gaattttcag ggtaaactgg   1320

ccatccgaaa atagcaacaa cccagactgg ctcctcactc ccttttccat cactaaaaat   1380

cacagagcag tcagagggac ccagtaagac caaaggaggg gaggacagag catgaaaacc   1440

aaaatccatg caaatgaaat gtaattggca cgaccctcac ccccaaatct tacatctcaa   1500

ttcccatcct aaaaagcact catactttat gcatccccgc agctacacac acacaacaca   1560

cagcacacgc atgaacacag cacacacacg agcacagcac acacacaaac gcacagcaca   1620

cacagcacac agatgagcac acagcacaca cacaaacgca cagcacacac acgcacacac   1680

atgcacacac agcacacaaa cgcacggcac acacacgcac acacatgcac acacagcaca   1740

cacacaaacg cacagcacac acaaacgcac agcacacacg cacacacagc acacacacga   1800

gcacacagca cacaaacgca cagcacacgc acacacatgc acacacagca cacacactag   1860

cacacagcac acacacaaag acacagcaca cacatgcaca cacagcacac acacgcgaac   1920

acagcacaca cgaacacagc acacacagca cacacacaaa cacagcacac acatgcacac   1980

agcacacgca cacacagcac acacatgaac acagcacaca gcacacacat gcacacacag   2040

cacacacgca tgcacagcac acatgaacac agcacacaca caaacacaca gcacacacat   2100

gcacacacag cacacacact catgcgcagc acatacatga acacagctca cagcacacaa   2160

acacgcagca cacacgttgc acacgcaagc acccacctgc acacacacat gcgcacacac   2220

acgcacaccc ccacaaaatt ggatgaaaac aataagcata tctaagcaac tacgatatct   2280

gtatggatca ggccaaagtc ccgctaagat tctccaatgt tttcatggtc tgagccccgc   2340

tcctgttccc atctccactg cccctcggcc ctgtctgtgc cctgcctctc agaggagggg   2400

gctcagatgg tgcggcctga gtgtgcggcc ggcggcattt gggatacacc cgtagggtgg   2460

gcggggtgtg tcccaggcct aattccatct ttccaccatg acagagatgc ccttgtgagg   2520

ctggcctcct tggcgcctgt ccccacggcc cccgcagcgt gagccacgat gctccccata   2580

ccccacccat tcccgataca ccttacttac tgtgtgttgg cccagccaga gtgaggaagg   2640

agtttggcca cattggagat ggcggtagct gagcagacat gcccccacga gtagcctgac   2700

tccctggtgt gctcctggaa ggaagatctt ggggaccccc ccaccggagc acacctaggg   2760

atcatctttg cccgtctcct ggggaccccc caagaaatgt ggagtcctcg ggggccgtgc   2820

actgatgcgg ggagtgtggg aagtctggcg gttggagggg tgggtggggg gcagtggggg   2880

ctgggcgggg ggagttctgg ggtaggaagt ggtcccggga gattttggat ggaaaagtca   2940

ggaggattga cagcagactt gcagaattac atagagaaat taggaacccc caaatttcat   3000

gtcaattgat ctattccccc tctttgtttc ttggggcatt tttccttttt tttttttttt   3060

tgtttttttt ttacccctcc ttagctttat gcgctcagaa accaaattaa accccccccc   3120

catgtaacag gggggcagtg acaaaagcaa gaacgcacga agccagcctg gagaccacca   3180

cgtcctgccc cccgccattt atcgccctga ttggattttg tttttcatct gtccctgttg   3240

cttgggttga gttgagggtg gagcctcctg gggggcactg gccactgagc ccccttggag   3300

aagtcagagg ggagtggaga aggccactgt ccggcctggc ttctggggac agtggctggt   3360

ccccagaagt cctgagggcg gagggggggg ttgggcaggg tctcctcagg tgtcaggagg   3420

gtgctcggag gccacaggag ggggctcctg gctggcctga ggctggccgg aggggaaggg   3480

gctagcaggt gtgtaaacag agggttccat caggctgggg cagggtggcc gccttccgca   3540

cacttgagga accctcccct ctccctcggt gacatcttgc ccgcccctca gcaccctgcc   3600

ttgtctccag gaggtccgaa gctctgtggg acctcttggg ggcaaggtgg ggtgaggccg   3660

gggagtaggg aggtcaggcg ggtctgagcc cacagagcag gagagctgcc aggtctgccc   3720

atcgaccagg ttgcttgggc cccggagccc acgggtctgg tgatgccata gcagccacca   3780

ccgcggcgcc tagggctgcg gcagggactc ggcctctggg aggtttacct cgcccccact   3840

tgtgccccca gctcagcccc cctgcacgca gcccgactag cagtctagag gcctgaggct   3900

tctgggtcct ggtgacgggg ctggcatgac cccgggggtc gtccatgcca gtccgcctca   3960

gtcgcagagg gtccctcggc aagcgccctg tgagtgggcc attcggaaca ttggacagaa   4020

gcccaaagag ccaaattgtc acaattgtgg aacccacatt ggcctgagat ccaaaacgct   4080

tcgaggcacc ccaaattacc tgcccattcg tcaggacacc cacccaccca gtgttatatt   4140

ctgcctcgcc ggagtgggtg ttcccggggg cacttgccga ccagcccctt gcgtccccag   4200

gtttgcagct ctcccctggg ccactaacca tcctggcccg ggctgcctgt ctgacctccg   4260

tgcctagtcg tggctctcca tcttgtctcc tccccgtgtc cccaatgtct tcagtggggg   4320

gccccctctt gggtcccctc ctctgccatc acctgaagac ccccacgcca aacactgaat   4380

gtcacctgtg cctgccgcct cggtccacct tgcggcccgt gtttgactca actcaactcc   4440

tttaacgcta atatttccgg caaaatccca tgcttgggtt ttgtctttaa ccttgtaacg   4500

cttgcaatcc caataaagca ttaaaagtca tgatcttc                           4538


<210>  7711
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7711

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7712
<211>  4527
<212>  DNA
<213>  Homo sapiens

<400>  7712
gagaggggct gctggtctga ggctaagaag ggcagagcct tcgacccgga gagaggccgc     60

ggcccctgcc cagtgggcag cgtggaagtt tccatacaag gagacaccaa tgggaatccc    120

aatggggaag tcgatgctgg tgcttctcac cttcttggcc ttcgcctcgt gctgcattgc    180

tgcttaccgc cccagtgaga ccctgtgcgg cggggagctg gtggacaccc tccagttcgt    240

ctgtggggac cgcggcttct acttcagcag gcccgcaagc cgtgtgagcc gtcgcagccg    300

tggcatcgtt gaggagtgct gtttccgcag ctgtgacctg gccctcctgg agacgtactg    360

tgctaccccc gccaagtccg agagggacgt gtcgacccct ccgaccgtgc ttccggacaa    420

cttccccaga taccccgtgg gcaagttctt ccaatatgac acctggaagc agtccaccca    480

gcgcctgcgc aggggcctgc ctgccctcct gcgtgcccgc cggggtcacg tgctcgccaa    540

ggagctcgag gcgttcaggg aggccaaacg tcaccgtccc ctgattgctc tacccaccca    600

agaccccgcc cacgggggcg cccccccaga gatggccagc aatcggaagt gagcaaaact    660

gccgcaagtc tgcagcccgg cgccaccatc ctgcagcctc ctcctgacca cggacgtttc    720

catcaggttc catcccgaaa atctctcggt tccacgtccc cctggggctt ctcctgaccc    780

agtccccgtg ccccgcctcc ccgaaacagg ctactctcct cggccccctc catcgggctg    840

aggaagcaca gcagcatctt caaacatgta caaaatcgat tggctttaaa cacccttcac    900

ataccctccc cccaaattat ccccaattat ccccacacat aaaaaatcaa aacattaaac    960

taaccccctt cccccccccc cacaacaacc ctcttaaaac taattggctt tttagaaaca   1020

ccccacaaaa gctcagaaat tggctttaaa aaaaacaacc accaaaaaaa atcaattggc   1080

taaaaaaaaa aagtattaaa aacgaattgg ctgagaaaca attggcaaaa taaaggaatt   1140

tggcactccc cacccccctc tttctcttct cccttggact ttgagtcaaa ttggcctgga   1200

cttgagtccc tgaaccagca aagagaaaag aaggacccca gaaatcacag gtgggcacgt   1260

cgctgctacc gccatctccc ttctcacggg aattttcagg gtaaactggc catccgaaaa   1320

tagcaacaac ccagactggc tcctcactcc cttttccatc actaaaaatc acagagcagt   1380

cagagggacc cagtaagacc aaaggagggg aggacagagc atgaaaacca aaatccatgc   1440

aaatgaaatg taattggcac gaccctcacc cccaaatctt acatctcaat tcccatccta   1500

aaaagcactc atactttatg catccccgca gctacacaca cacaacacac agcacacgca   1560

tgaacacagc acacacacga gcacagcaca cacacaaacg cacagcacac acagcacaca   1620

gatgagcaca cagcacacac acaaacgcac agcacacaca cgcacacaca tgcacacaca   1680

gcacacaaac gcacggcaca cacacgcaca cacatgcaca cacagcacac acacaaacgc   1740

acagcacaca caaacgcaca gcacacacgc acacacagca cacacacgag cacacagcac   1800

acaaacgcac agcacacgca cacacatgca cacacagcac acacactagc acacagcaca   1860

cacacaaaga cacagcacac acatgcacac acagcacaca cacgcgaaca cagcacacac   1920

gaacacagca cacacagcac acacacaaac acagcacaca catgcacaca gcacacgcac   1980

acacagcaca cacatgaaca cagcacacag cacacacatg cacacacagc acacacgcat   2040

gcacagcaca catgaacaca gcacacacac aaacacacag cacacacatg cacacacagc   2100

acacacactc atgcgcagca catacatgaa cacagctcac agcacacaaa cacgcagcac   2160

acacgttgca cacgcaagca cccacctgca cacacacatg cgcacacaca cgcacacccc   2220

cacaaaattg gatgaaaaca ataagcatat ctaagcaact acgatatctg tatggatcag   2280

gccaaagtcc cgctaagatt ctccaatgtt ttcatggtct gagccccgct cctgttccca   2340

tctccactgc ccctcggccc tgtctgtgcc ctgcctctca gaggaggggg ctcagatggt   2400

gcggcctgag tgtgcggccg gcggcatttg ggatacaccc gtagggtggg cggggtgtgt   2460

cccaggccta attccatctt tccaccatga cagagatgcc cttgtgaggc tggcctcctt   2520

ggcgcctgtc cccacggccc ccgcagcgtg agccacgatg ctccccatac cccacccatt   2580

cccgatacac cttacttact gtgtgttggc ccagccagag tgaggaagga gtttggccac   2640

attggagatg gcggtagctg agcagacatg cccccacgag tagcctgact ccctggtgtg   2700

ctcctggaag gaagatcttg gggacccccc caccggagca cacctaggga tcatctttgc   2760

ccgtctcctg gggacccccc aagaaatgtg gagtcctcgg gggccgtgca ctgatgcggg   2820

gagtgtggga agtctggcgg ttggaggggt gggtgggggg cagtgggggc tgggcggggg   2880

gagttctggg gtaggaagtg gtcccgggag attttggatg gaaaagtcag gaggattgac   2940

agcagacttg cagaattaca tagagaaatt aggaaccccc aaatttcatg tcaattgatc   3000

tattccccct ctttgtttct tggggcattt ttcctttttt tttttttttt gttttttttt   3060

tacccctcct tagctttatg cgctcagaaa ccaaattaaa cccccccccc atgtaacagg   3120

ggggcagtga caaaagcaag aacgcacgaa gccagcctgg agaccaccac gtcctgcccc   3180

ccgccattta tcgccctgat tggattttgt ttttcatctg tccctgttgc ttgggttgag   3240

ttgagggtgg agcctcctgg ggggcactgg ccactgagcc cccttggaga agtcagaggg   3300

gagtggagaa ggccactgtc cggcctggct tctggggaca gtggctggtc cccagaagtc   3360

ctgagggcgg aggggggggt tgggcagggt ctcctcaggt gtcaggaggg tgctcggagg   3420

ccacaggagg gggctcctgg ctggcctgag gctggccgga ggggaagggg ctagcaggtg   3480

tgtaaacaga gggttccatc aggctggggc agggtggccg ccttccgcac acttgaggaa   3540

ccctcccctc tccctcggtg acatcttgcc cgcccctcag caccctgcct tgtctccagg   3600

aggtccgaag ctctgtggga cctcttgggg gcaaggtggg gtgaggccgg ggagtaggga   3660

ggtcaggcgg gtctgagccc acagagcagg agagctgcca ggtctgccca tcgaccaggt   3720

tgcttgggcc ccggagccca cgggtctggt gatgccatag cagccaccac cgcggcgcct   3780

agggctgcgg cagggactcg gcctctggga ggtttacctc gcccccactt gtgcccccag   3840

ctcagccccc ctgcacgcag cccgactagc agtctagagg cctgaggctt ctgggtcctg   3900

gtgacggggc tggcatgacc ccgggggtcg tccatgccag tccgcctcag tcgcagaggg   3960

tccctcggca agcgccctgt gagtgggcca ttcggaacat tggacagaag cccaaagagc   4020

caaattgtca caattgtgga acccacattg gcctgagatc caaaacgctt cgaggcaccc   4080

caaattacct gcccattcgt caggacaccc acccacccag tgttatattc tgcctcgccg   4140

gagtgggtgt tcccgggggc acttgccgac cagccccttg cgtccccagg tttgcagctc   4200

tcccctgggc cactaaccat cctggcccgg gctgcctgtc tgacctccgt gcctagtcgt   4260

ggctctccat cttgtctcct ccccgtgtcc ccaatgtctt cagtgggggg ccccctcttg   4320

ggtcccctcc tctgccatca cctgaagacc cccacgccaa acactgaatg tcacctgtgc   4380

ctgccgcctc ggtccacctt gcggcccgtg tttgactcaa ctcaactcct ttaacgctaa   4440

tatttccggc aaaatcccat gcttgggttt tgtctttaac cttgtaacgc ttgcaatccc   4500

aataaagcat taaaagtcat gatcttc                                       4527


<210>  7713
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7713

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7714
<211>  4094
<212>  DNA
<213>  Homo sapiens

<400>  7714
ccccagtcac cgcctccccc ggcccctcga cgtggcgccc ttccctccgc ttctctgtgc     60

tccccgcgcc cctcttggcg tctggccccg gcccccgctc tttctcccgc aaccttccct    120

tcgctccctc ccgtcccccc cagctcctag cctccgactc cctccccccc tcacgcccgc    180

cctctcgcct tcgccgaacc aaagtggatt aattacacgc tttctgtttc tctccgtgct    240

gttctctccc gctgtgcgcc tgcccgcctc tcgctgtcct ctctccccct cgccctctct    300

tcggcccccc cctttcacgt tcactctgtc tctcccacta tctctgcccc cctctatcct    360

tgatacaaca gctgacctca tttcccgata ccttttcccc cccgaaaagt acaacatctg    420

gcccgcccca gcccgaagac agcccgtcct ccctggacaa tcagacgaat tcctcccccc    480

aaattatccc caattatccc cacacataaa aaatcaaaac attaaactaa cccccttccc    540

ccccccccac aacaaccctc ttaaaactaa ttggcttttt agaaacaccc cacaaaagct    600

cagaaattgg ctttaaaaaa aacaaccacc aaaaaaaatc aattggctaa aaaaaaaaag    660

tattaaaaac gaattggctg agaaacaatt ggcaaaataa aggaatttgg cactccccac    720

ccccctcttt ctcttctccc ttggactttg agtcaaattg gcctggactt gagtccctga    780

accagcaaag agaaaagaag gaccccagaa atcacaggtg ggcacgtcgc tgctaccgcc    840

atctcccttc tcacgggaat tttcagggta aactggccat ccgaaaatag caacaaccca    900

gactggctcc tcactccctt ttccatcact aaaaatcaca gagcagtcag agggacccag    960

taagaccaaa ggaggggagg acagagcatg aaaaccaaaa tccatgcaaa tgaaatgtaa   1020

ttggcacgac cctcaccccc aaatcttaca tctcaattcc catcctaaaa agcactcata   1080

ctttatgcat ccccgcagct acacacacac aacacacagc acacgcatga acacagcaca   1140

cacacgagca cagcacacac acaaacgcac agcacacaca gcacacagat gagcacacag   1200

cacacacaca aacgcacagc acacacacgc acacacatgc acacacagca cacaaacgca   1260

cggcacacac acgcacacac atgcacacac agcacacaca caaacgcaca gcacacacaa   1320

acgcacagca cacacgcaca cacagcacac acacgagcac acagcacaca aacgcacagc   1380

acacgcacac acatgcacac acagcacaca cactagcaca cagcacacac acaaagacac   1440

agcacacaca tgcacacaca gcacacacac gcgaacacag cacacacgaa cacagcacac   1500

acagcacaca cacaaacaca gcacacacat gcacacagca cacgcacaca cagcacacac   1560

atgaacacag cacacagcac acacatgcac acacagcaca cacgcatgca cagcacacat   1620

gaacacagca cacacacaaa cacacagcac acacatgcac acacagcaca cacactcatg   1680

cgcagcacat acatgaacac agctcacagc acacaaacac gcagcacaca cgttgcacac   1740

gcaagcaccc acctgcacac acacatgcgc acacacacgc acacccccac aaaattggat   1800

gaaaacaata agcatatcta agcaactacg atatctgtat ggatcaggcc aaagtcccgc   1860

taagattctc caatgttttc atggtctgag ccccgctcct gttcccatct ccactgcccc   1920

tcggccctgt ctgtgccctg cctctcagag gagggggctc agatggtgcg gcctgagtgt   1980

gcggccggcg gcatttggga tacacccgta gggtgggcgg ggtgtgtccc aggcctaatt   2040

ccatctttcc accatgacag agatgccctt gtgaggctgg cctccttggc gcctgtcccc   2100

acggcccccg cagcgtgagc cacgatgctc cccatacccc acccattccc gatacacctt   2160

acttactgtg tgttggccca gccagagtga ggaaggagtt tggccacatt ggagatggcg   2220

gtagctgagc agacatgccc ccacgagtag cctgactccc tggtgtgctc ctggaaggaa   2280

gatcttgggg acccccccac cggagcacac ctagggatca tctttgcccg tctcctgggg   2340

accccccaag aaatgtggag tcctcggggg ccgtgcactg atgcggggag tgtgggaagt   2400

ctggcggttg gaggggtggg tggggggcag tgggggctgg gcggggggag ttctggggta   2460

ggaagtggtc ccgggagatt ttggatggaa aagtcaggag gattgacagc agacttgcag   2520

aattacatag agaaattagg aacccccaaa tttcatgtca attgatctat tccccctctt   2580

tgtttcttgg ggcatttttc cttttttttt tttttttgtt ttttttttac ccctccttag   2640

ctttatgcgc tcagaaacca aattaaaccc cccccccatg taacaggggg gcagtgacaa   2700

aagcaagaac gcacgaagcc agcctggaga ccaccacgtc ctgccccccg ccatttatcg   2760

ccctgattgg attttgtttt tcatctgtcc ctgttgcttg ggttgagttg agggtggagc   2820

ctcctggggg gcactggcca ctgagccccc ttggagaagt cagaggggag tggagaaggc   2880

cactgtccgg cctggcttct ggggacagtg gctggtcccc agaagtcctg agggcggagg   2940

ggggggttgg gcagggtctc ctcaggtgtc aggagggtgc tcggaggcca caggaggggg   3000

ctcctggctg gcctgaggct ggccggaggg gaaggggcta gcaggtgtgt aaacagaggg   3060

ttccatcagg ctggggcagg gtggccgcct tccgcacact tgaggaaccc tcccctctcc   3120

ctcggtgaca tcttgcccgc ccctcagcac cctgccttgt ctccaggagg tccgaagctc   3180

tgtgggacct cttgggggca aggtggggtg aggccgggga gtagggaggt caggcgggtc   3240

tgagcccaca gagcaggaga gctgccaggt ctgcccatcg accaggttgc ttgggccccg   3300

gagcccacgg gtctggtgat gccatagcag ccaccaccgc ggcgcctagg gctgcggcag   3360

ggactcggcc tctgggaggt ttacctcgcc cccacttgtg cccccagctc agcccccctg   3420

cacgcagccc gactagcagt ctagaggcct gaggcttctg ggtcctggtg acggggctgg   3480

catgaccccg ggggtcgtcc atgccagtcc gcctcagtcg cagagggtcc ctcggcaagc   3540

gccctgtgag tgggccattc ggaacattgg acagaagccc aaagagccaa attgtcacaa   3600

ttgtggaacc cacattggcc tgagatccaa aacgcttcga ggcaccccaa attacctgcc   3660

cattcgtcag gacacccacc cacccagtgt tatattctgc ctcgccggag tgggtgttcc   3720

cgggggcact tgccgaccag ccccttgcgt ccccaggttt gcagctctcc cctgggccac   3780

taaccatcct ggcccgggct gcctgtctga cctccgtgcc tagtcgtggc tctccatctt   3840

gtctcctccc cgtgtcccca atgtcttcag tggggggccc cctcttgggt cccctcctct   3900

gccatcacct gaagaccccc acgccaaaca ctgaatgtca cctgtgcctg ccgcctcggt   3960

ccaccttgcg gcccgtgttt gactcaactc aactccttta acgctaatat ttccggcaaa   4020

atcccatgct tgggttttgt ctttaacctt gtaacgcttg caatcccaat aaagcattaa   4080

aagtcatgat cttc                                                     4094


<210>  7715
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  7715

Met His Thr Gln His Thr His Ala Asn Thr Ala His Thr Asn Thr Ala 
1               5                   10                  15


His Thr Ala His Thr Gln Thr Gln His Thr His Ala His Ser Thr Arg 
            20                  25                  30


Thr His Ser Thr His Met Asn Thr Ala His Ser Thr His Met His Thr 
        35                  40                  45


Gln His Thr Arg Met His Ser Thr His Glu His Ser Thr His Thr Asn 
    50                  55                  60


Thr Gln His Thr His Ala His Thr Ala His Thr Leu Met Arg Ser Thr 
65                  70                  75                  80


Tyr Met Asn Thr Ala His Ser Thr Gln Thr Arg Ser Thr His Val Ala 
                85                  90                  95


His Ala Ser Thr His Leu His Thr His Met Arg Thr His Thr His Thr 
            100                 105                 110


Pro Thr Lys Leu Asp Glu Asn Asn Lys His Ile 
        115                 120


<210>  7716
<211>  5461
<212>  DNA
<213>  Homo sapiens

<400>  7716
cctgtccccc tcccgaggcc cgggctcgcg acggcagagg gctccgtcgg cccaaaccga     60

gctgggcgcc cgcggtccgg gtgcagcctc cactccgccc cccagtcacc gcctcccccg    120

gcccctcgac gtggcgccct tccctccgct tctctgtgct ccccgcgccc ctcttggcgt    180

ctggccccgg cccccgctct ttctcccgca accttccctt cgctccctcc cgtccccccc    240

agctcctagc ctccgactcc ctccccccct cacgcccgcc ctctcgcctt cgccgaacca    300

aagtggatta attacacgct ttctgtttct ctccgtgctg ttctctcccg ctgtgcgcct    360

gcccgcctct cgctgtcctc tctccccctc gccctctctt cggccccccc ctttcacgtt    420

cactctgtct ctcccactat ctctgccccc ctctatcctt gatacaacag ctgacctcat    480

ttcccgatac cttttccccc ccgaaaagta caacatctgg cccgccccag cccgaagaca    540

gcccgtcctc cctggacaat cagacgaatt ctcccccccc ccccaaaaaa aagccatccc    600

cccgctctgc cccgtcgcac attcggcccc cgcgactcgg ccagagcggc gctggcagag    660

gagtgtccgg caggagggcc aacgcccgct gttcggtttg cgacacgcag cagggaggtg    720

ggcggcagcg tcgccggctt ccagacacca atgggaatcc caatggggaa gtcgatgctg    780

gtgcttctca ccttcttggc cttcgcctcg tgctgcattg ctgcttaccg ccccagtgag    840

accctgtgcg gcggggagct ggtggacacc ctccagttcg tctgtgggga ccgcggcttc    900

tacttcagca ggcccgcaag ccgtgtgagc cgtcgcagcc gtggcatcgt tgaggagtgc    960

tgtttccgca gctgtgacct ggccctcctg gagacgtact gtgctacccc cgccaagtcc   1020

gagagggacg tgtcgacccc tccgaccgtg cttccggtga gggtcctggg cccctttccc   1080

actctctaga gacagagaaa tagggcttcg ggcgcccagc gtttcctgtg gcctctggga   1140

cctcttggcc agggacaagg acccgtgact tccttgcttg ctgtgtggcc cgggagcagc   1200

tcagacgctg gctccttctg tccctctgcc cgtggacatt agctcaagtc actgatcagt   1260

cacaggggtg gcctgtcagg tcaggcgggc ggctcaggcg gaagagcgtg gagagcaggc   1320

acctgctgac cagccccttc ccctcccagg acaacttccc cagatacccc gtgggcaagt   1380

tcttccaata tgacacctgg aagcagtcca cccagcgcct gcgcaggggc ctgcctgccc   1440

tcctgcgtgc ccgccggggt cacgtgctcg ccaaggagct cgaggcgttc agggaggcca   1500

aacgtcaccg tcccctgatt gctctaccca cccaagaccc cgcccacggg ggcgcccccc   1560

cagagatggc cagcaatcgg aagtgagcaa aactgccgca agtctgcagc ccggcgccac   1620

catcctgcag cctcctcctg accacggacg tttccatcag gttccatccc gaaaatctct   1680

cggttccacg tccccctggg gcttctcctg acccagtccc cgtgccccgc ctccccgaaa   1740

caggctactc tcctcggccc cctccatcgg gctgaggaag cacagcagca tcttcaaaca   1800

tgtacaaaat cgattggctt taaacaccct tcacataccc tccccccaaa ttatccccaa   1860

ttatccccac acataaaaaa tcaaaacatt aaactaaccc ccttcccccc cccccacaac   1920

aaccctctta aaactaattg gctttttaga aacaccccac aaaagctcag aaattggctt   1980

taaaaaaaac aaccaccaaa aaaaatcaat tggctaaaaa aaaaaagtat taaaaacgaa   2040

ttggctgaga aacaattggc aaaataaagg aatttggcac tccccacccc cctctttctc   2100

ttctcccttg gactttgagt caaattggcc tggacttgag tccctgaacc agcaaagaga   2160

aaagaaggac cccagaaatc acaggtgggc acgtcgctgc taccgccatc tcccttctca   2220

cgggaatttt cagggtaaac tggccatccg aaaatagcaa caacccagac tggctcctca   2280

ctcccttttc catcactaaa aatcacagag cagtcagagg gacccagtaa gaccaaagga   2340

ggggaggaca gagcatgaaa accaaaatcc atgcaaatga aatgtaattg gcacgaccct   2400

cacccccaaa tcttacatct caattcccat cctaaaaagc actcatactt tatgcatccc   2460

cgcagctaca cacacacaac acacagcaca cgcatgaaca cagcacacac acgagcacag   2520

cacacacaca aacgcacagc acacacagca cacagatgag cacacagcac acacacaaac   2580

gcacagcaca cacacgcaca cacatgcaca cacagcacac aaacgcacgg cacacacacg   2640

cacacacatg cacacacagc acacacacaa acgcacagca cacacaaacg cacagcacac   2700

acgcacacac agcacacaca cgagcacaca gcacacaaac gcacagcaca cgcacacaca   2760

tgcacacaca gcacacacac tagcacacag cacacacaca aagacacagc acacacatgc   2820

acacacagca cacacacgcg aacacagcac acacgaacac agcacacaca gcacacacac   2880

aaacacagca cacacatgca cacagcacac gcacacacag cacacacatg aacacagcac   2940

acagcacaca catgcacaca cagcacacac gcatgcacag cacacatgaa cacagcacac   3000

acacaaacac acagcacaca catgcacaca cagcacacac actcatgcgc agcacataca   3060

tgaacacagc tcacagcaca caaacacgca gcacacacgt tgcacacgca agcacccacc   3120

tgcacacaca catgcgcaca cacacgcaca cccccacaaa attggatgaa aacaataagc   3180

atatctaagc aactacgata tctgtatgga tcaggccaaa gtcccgctaa gattctccaa   3240

tgttttcatg gtctgagccc cgctcctgtt cccatctcca ctgcccctcg gccctgtctg   3300

tgccctgcct ctcagaggag ggggctcaga tggtgcggcc tgagtgtgcg gccggcggca   3360

tttgggatac acccgtaggg tgggcggggt gtgtcccagg cctaattcca tctttccacc   3420

atgacagaga tgcccttgtg aggctggcct ccttggcgcc tgtccccacg gcccccgcag   3480

cgtgagccac gatgctcccc ataccccacc cattcccgat acaccttact tactgtgtgt   3540

tggcccagcc agagtgagga aggagtttgg ccacattgga gatggcggta gctgagcaga   3600

catgccccca cgagtagcct gactccctgg tgtgctcctg gaaggaagat cttggggacc   3660

cccccaccgg agcacaccta gggatcatct ttgcccgtct cctggggacc ccccaagaaa   3720

tgtggagtcc tcgggggccg tgcactgatg cggggagtgt gggaagtctg gcggttggag   3780

gggtgggtgg ggggcagtgg gggctgggcg gggggagttc tggggtagga agtggtcccg   3840

ggagattttg gatggaaaag tcaggaggat tgacagcaga cttgcagaat tacatagaga   3900

aattaggaac ccccaaattt catgtcaatt gatctattcc ccctctttgt ttcttggggc   3960

atttttcctt tttttttttt ttttgttttt tttttacccc tccttagctt tatgcgctca   4020

gaaaccaaat taaacccccc ccccatgtaa caggggggca gtgacaaaag caagaacgca   4080

cgaagccagc ctggagacca ccacgtcctg ccccccgcca tttatcgccc tgattggatt   4140

ttgtttttca tctgtccctg ttgcttgggt tgagttgagg gtggagcctc ctggggggca   4200

ctggccactg agcccccttg gagaagtcag aggggagtgg agaaggccac tgtccggcct   4260

ggcttctggg gacagtggct ggtccccaga agtcctgagg gcggaggggg gggttgggca   4320

gggtctcctc aggtgtcagg agggtgctcg gaggccacag gagggggctc ctggctggcc   4380

tgaggctggc cggaggggaa ggggctagca ggtgtgtaaa cagagggttc catcaggctg   4440

gggcagggtg gccgccttcc gcacacttga ggaaccctcc cctctccctc ggtgacatct   4500

tgcccgcccc tcagcaccct gccttgtctc caggaggtcc gaagctctgt gggacctctt   4560

gggggcaagg tggggtgagg ccggggagta gggaggtcag gcgggtctga gcccacagag   4620

caggagagct gccaggtctg cccatcgacc aggttgcttg ggccccggag cccacgggtc   4680

tggtgatgcc atagcagcca ccaccgcggc gcctagggct gcggcaggga ctcggcctct   4740

gggaggttta cctcgccccc acttgtgccc ccagctcagc ccccctgcac gcagcccgac   4800

tagcagtcta gaggcctgag gcttctgggt cctggtgacg gggctggcat gaccccgggg   4860

gtcgtccatg ccagtccgcc tcagtcgcag agggtccctc ggcaagcgcc ctgtgagtgg   4920

gccattcgga acattggaca gaagcccaaa gagccaaatt gtcacaattg tggaacccac   4980

attggcctga gatccaaaac gcttcgaggc accccaaatt acctgcccat tcgtcaggac   5040

acccacccac ccagtgttat attctgcctc gccggagtgg gtgttcccgg gggcacttgc   5100

cgaccagccc cttgcgtccc caggtttgca gctctcccct gggccactaa ccatcctggc   5160

ccgggctgcc tgtctgacct ccgtgcctag tcgtggctct ccatcttgtc tcctccccgt   5220

gtccccaatg tcttcagtgg ggggccccct cttgggtccc ctcctctgcc atcacctgaa   5280

gacccccacg ccaaacactg aatgtcacct gtgcctgccg cctcggtcca ccttgcggcc   5340

cgtgtttgac tcaactcaac tcctttaacg ctaatatttc cggcaaaatc ccatgcttgg   5400

gttttgtctt taaccttgta acgcttgcaa tcccaataaa gcattaaaag tcatgatctt   5460

c                                                                   5461


<210>  7717
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  7717

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Val Arg Val Leu Gly Pro Phe Pro Thr Leu 
            100                 105                 110


<210>  7718
<211>  5553
<212>  DNA
<213>  Homo sapiens

<400>  7718
gccggccccg gcccccccct tccggccgcc cccgcctcct ggcccacgcc tgcccgcgct     60

ctgcccacca gcgcctccat cgggcaaggc ggccccgcgt cgacgccgcc cgctgcctcg    120

ctgctgactc ccgtcccggg cgccgtccgc ggggtcgcgc tccgccgggc ctgcggattc    180

cccgccgcct cctcttcatc tacctcaact ccccccatcc ccgcttcgcc cgaggaggcg    240

gttccccccg caggcagtcc ggctcgcagg ccgccggcgt tgtcaccccc ccccgcgctc    300

cccctccagc cctccccccg gcgcgcagcc tcgggccgct cccctttccg cgctgcgtcc    360

cggagcggcc ccggtgccgc caccgcctgt ccccctcccg aggcccgggc tcgcgacggc    420

agagggctcc gtcggcccaa accgagctgg gcgcccgcgg tccgggtgca gcctccactc    480

cgccccccag tcaccgcctc ccccggcccc tcgacgtggc gcccttccct ccgcttctct    540

gtgctccccg cgcccctctt ggcgtctggc cccggccccc gctctttctc ccgcaacctt    600

cccttcgctc cctcccgtcc cccccagctc ctagcctccg actccctccc cccctcacgc    660

ccgccctctc gccttcgccg aaccaaagtg gattaattac acgctttctg tttctctccg    720

tgctgttctc tcccgctgtg cgcctgcccg cctctcgctg tcctctctcc ccctcgccct    780

ctcttcggcc cccccctttc acgttcactc tgtctctccc actatctctg cccccctcta    840

tccttgatac aacagctgac ctcatttccc gatacctttt cccccccgaa aagtacaaca    900

tctggcccgc cccagcccga agacagcccg tcctccctgg acaatcagac gaattctccc    960

ccccccccca aaaaaaagcc atccccccgc tctgccccgt cgcacattcg gcccccgcga   1020

ctcggccaga gcggcgctgg cagaggagtg tccggcagga gggccaacgc ccgctgttcg   1080

gtttgcgaca cgcagcaggg aggtgggcgg cagcgtcgcc ggcttccaga caccaatggg   1140

aatcccaatg gggaagtcga tgctggtgct tctcaccttc ttggccttcg cctcgtgctg   1200

cattgctgct taccgcccca gtgagaccct gtgcggcggg gagctggtgg acaccctcca   1260

gttcgtctgt ggggaccgcg gcttctactt cagcaggccc gcaagccgtg tgagccgtcg   1320

cagccgtggc atcgttgagg agtgctgttt ccgcagctgt gacctggccc tcctggagac   1380

gtactgtgct acccccgcca agtccgagag ggacgtgtcg acccctccga ccgtgcttcc   1440

ggacaacttc cccagatacc ccgtgggcaa gttcttccaa tatgacacct ggaagcagtc   1500

cacccagcgc ctgcgcaggg gcctgcctgc cctcctgcgt gcccgccggg gtcacgtgct   1560

cgccaaggag ctcgaggcgt tcagggaggc caaacgtcac cgtcccctga ttgctctacc   1620

cacccaagac cccgcccacg ggggcgcccc cccagagatg gccagcaatc ggaagtgagc   1680

aaaactgccg caagtctgca gcccggcgcc accatcctgc agcctcctcc tgaccacgga   1740

cgtttccatc aggttccatc ccgaaaatct ctcggttcca cgtccccctg gggcttctcc   1800

tgacccagtc cccgtgcccc gcctccccga aacaggctac tctcctcggc cccctccatc   1860

gggctgagga agcacagcag catcttcaaa catgtacaaa atcgattggc tttaaacacc   1920

cttcacatac cctcccccca aattatcccc aattatcccc acacataaaa aatcaaaaca   1980

ttaaactaac ccccttcccc cccccccaca acaaccctct taaaactaat tggcttttta   2040

gaaacacccc acaaaagctc agaaattggc tttaaaaaaa acaaccacca aaaaaaatca   2100

attggctaaa aaaaaaaagt attaaaaacg aattggctga gaaacaattg gcaaaataaa   2160

ggaatttggc actccccacc cccctctttc tcttctccct tggactttga gtcaaattgg   2220

cctggacttg agtccctgaa ccagcaaaga gaaaagaagg accccagaaa tcacaggtgg   2280

gcacgtcgct gctaccgcca tctcccttct cacgggaatt ttcagggtaa actggccatc   2340

cgaaaatagc aacaacccag actggctcct cactcccttt tccatcacta aaaatcacag   2400

agcagtcaga gggacccagt aagaccaaag gaggggagga cagagcatga aaaccaaaat   2460

ccatgcaaat gaaatgtaat tggcacgacc ctcaccccca aatcttacat ctcaattccc   2520

atcctaaaaa gcactcatac tttatgcatc cccgcagcta cacacacaca acacacagca   2580

cacgcatgaa cacagcacac acacgagcac agcacacaca caaacgcaca gcacacacag   2640

cacacagatg agcacacagc acacacacaa acgcacagca cacacacgca cacacatgca   2700

cacacagcac acaaacgcac ggcacacaca cgcacacaca tgcacacaca gcacacacac   2760

aaacgcacag cacacacaaa cgcacagcac acacgcacac acagcacaca cacgagcaca   2820

cagcacacaa acgcacagca cacgcacaca catgcacaca cagcacacac actagcacac   2880

agcacacaca caaagacaca gcacacacat gcacacacag cacacacacg cgaacacagc   2940

acacacgaac acagcacaca cagcacacac acaaacacag cacacacatg cacacagcac   3000

acgcacacac agcacacaca tgaacacagc acacagcaca cacatgcaca cacagcacac   3060

acgcatgcac agcacacatg aacacagcac acacacaaac acacagcaca cacatgcaca   3120

cacagcacac acactcatgc gcagcacata catgaacaca gctcacagca cacaaacacg   3180

cagcacacac gttgcacacg caagcaccca cctgcacaca cacatgcgca cacacacgca   3240

cacccccaca aaattggatg aaaacaataa gcatatctaa gcaactacga tatctgtatg   3300

gatcaggcca aagtcccgct aagattctcc aatgttttca tggtctgagc cccgctcctg   3360

ttcccatctc cactgcccct cggccctgtc tgtgccctgc ctctcagagg agggggctca   3420

gatggtgcgg cctgagtgtg cggccggcgg catttgggat acacccgtag ggtgggcggg   3480

gtgtgtccca ggcctaattc catctttcca ccatgacaga gatgcccttg tgaggctggc   3540

ctccttggcg cctgtcccca cggcccccgc agcgtgagcc acgatgctcc ccatacccca   3600

cccattcccg atacacctta cttactgtgt gttggcccag ccagagtgag gaaggagttt   3660

ggccacattg gagatggcgg tagctgagca gacatgcccc cacgagtagc ctgactccct   3720

ggtgtgctcc tggaaggaag atcttgggga cccccccacc ggagcacacc tagggatcat   3780

ctttgcccgt ctcctgggga ccccccaaga aatgtggagt cctcgggggc cgtgcactga   3840

tgcggggagt gtgggaagtc tggcggttgg aggggtgggt ggggggcagt gggggctggg   3900

cggggggagt tctggggtag gaagtggtcc cgggagattt tggatggaaa agtcaggagg   3960

attgacagca gacttgcaga attacataga gaaattagga acccccaaat ttcatgtcaa   4020

ttgatctatt ccccctcttt gtttcttggg gcatttttcc tttttttttt ttttttgttt   4080

tttttttacc cctccttagc tttatgcgct cagaaaccaa attaaacccc ccccccatgt   4140

aacagggggg cagtgacaaa agcaagaacg cacgaagcca gcctggagac caccacgtcc   4200

tgccccccgc catttatcgc cctgattgga ttttgttttt catctgtccc tgttgcttgg   4260

gttgagttga gggtggagcc tcctgggggg cactggccac tgagccccct tggagaagtc   4320

agaggggagt ggagaaggcc actgtccggc ctggcttctg gggacagtgg ctggtcccca   4380

gaagtcctga gggcggaggg gggggttggg cagggtctcc tcaggtgtca ggagggtgct   4440

cggaggccac aggagggggc tcctggctgg cctgaggctg gccggagggg aaggggctag   4500

caggtgtgta aacagagggt tccatcaggc tggggcaggg tggccgcctt ccgcacactt   4560

gaggaaccct cccctctccc tcggtgacat cttgcccgcc cctcagcacc ctgccttgtc   4620

tccaggaggt ccgaagctct gtgggacctc ttgggggcaa ggtggggtga ggccggggag   4680

tagggaggtc aggcgggtct gagcccacag agcaggagag ctgccaggtc tgcccatcga   4740

ccaggttgct tgggccccgg agcccacggg tctggtgatg ccatagcagc caccaccgcg   4800

gcgcctaggg ctgcggcagg gactcggcct ctgggaggtt tacctcgccc ccacttgtgc   4860

ccccagctca gcccccctgc acgcagcccg actagcagtc tagaggcctg aggcttctgg   4920

gtcctggtga cggggctggc atgaccccgg gggtcgtcca tgccagtccg cctcagtcgc   4980

agagggtccc tcggcaagcg ccctgtgagt gggccattcg gaacattgga cagaagccca   5040

aagagccaaa ttgtcacaat tgtggaaccc acattggcct gagatccaaa acgcttcgag   5100

gcaccccaaa ttacctgccc attcgtcagg acacccaccc acccagtgtt atattctgcc   5160

tcgccggagt gggtgttccc gggggcactt gccgaccagc cccttgcgtc cccaggtttg   5220

cagctctccc ctgggccact aaccatcctg gcccgggctg cctgtctgac ctccgtgcct   5280

agtcgtggct ctccatcttg tctcctcccc gtgtccccaa tgtcttcagt ggggggcccc   5340

ctcttgggtc ccctcctctg ccatcacctg aagaccccca cgccaaacac tgaatgtcac   5400

ctgtgcctgc cgcctcggtc caccttgcgg cccgtgtttg actcaactca actcctttaa   5460

cgctaatatt tccggcaaaa tcccatgctt gggttttgtc tttaaccttg taacgcttgc   5520

aatcccaata aagcattaaa agtcatgatc ttc                                5553


<210>  7719
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7719

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7720
<211>  4971
<212>  DNA
<213>  Homo sapiens

<400>  7720
cactgcagct tccccaaccc cgcgcacagc gggcactggt ttcgggcctc tctgtctcct     60

acgaagtccc cagagcaact cggatttggg aaatttctct ctagcgttgc ccaaacacac    120

ttgggtcggc cgcgcgccct caggacgtgg acagggaggg cttccccgtg tccaggaaag    180

cgaccgggca ttgcccccag tctcccccaa atttgggcat tgtccccggg tcttccaacg    240

gactgggcgt tgctcccgga cactgaggac tggccccggg gtctcgctca ccttcagcag    300

cgtccaccgc ctgccacaga gcgttcgatc gctcgctgcc tgagctcctg gtgcgcccgc    360

ggacgcagcc tccagcttcg cggagatggt ttccccagac ccccaaatta tcgtggtggc    420

ccccgagacc gaactcgcgt ctatgcaagt ccaacgcact gaggacgggg taaccattat    480

ccagatattt tgggtgggcc gcaaaggcga gctacttaga cgcaccccgg tgagctcggc    540

catgcagaca ccaatgggaa tcccaatggg gaagtcgatg ctggtgcttc tcaccttctt    600

ggccttcgcc tcgtgctgca ttgctgctta ccgccccagt gagaccctgt gcggcgggga    660

gctggtggac accctccagt tcgtctgtgg ggaccgcggc ttctacttca gcaggcccgc    720

aagccgtgtg agccgtcgca gccgtggcat cgttgaggag tgctgtttcc gcagctgtga    780

cctggccctc ctggagacgt actgtgctac ccccgccaag tccgagaggg acgtgtcgac    840

ccctccgacc gtgcttccgg acaacttccc cagatacccc gtgggcaagt tcttccaata    900

tgacacctgg aagcagtcca cccagcgcct gcgcaggggc ctgcctgccc tcctgcgtgc    960

ccgccggggt cacgtgctcg ccaaggagct cgaggcgttc agggaggcca aacgtcaccg   1020

tcccctgatt gctctaccca cccaagaccc cgcccacggg ggcgcccccc cagagatggc   1080

cagcaatcgg aagtgagcaa aactgccgca agtctgcagc ccggcgccac catcctgcag   1140

cctcctcctg accacggacg tttccatcag gttccatccc gaaaatctct cggttccacg   1200

tccccctggg gcttctcctg acccagtccc cgtgccccgc ctccccgaaa caggctactc   1260

tcctcggccc cctccatcgg gctgaggaag cacagcagca tcttcaaaca tgtacaaaat   1320

cgattggctt taaacaccct tcacataccc tccccccaaa ttatccccaa ttatccccac   1380

acataaaaaa tcaaaacatt aaactaaccc ccttcccccc cccccacaac aaccctctta   1440

aaactaattg gctttttaga aacaccccac aaaagctcag aaattggctt taaaaaaaac   1500

aaccaccaaa aaaaatcaat tggctaaaaa aaaaaagtat taaaaacgaa ttggctgaga   1560

aacaattggc aaaataaagg aatttggcac tccccacccc cctctttctc ttctcccttg   1620

gactttgagt caaattggcc tggacttgag tccctgaacc agcaaagaga aaagaaggac   1680

cccagaaatc acaggtgggc acgtcgctgc taccgccatc tcccttctca cgggaatttt   1740

cagggtaaac tggccatccg aaaatagcaa caacccagac tggctcctca ctcccttttc   1800

catcactaaa aatcacagag cagtcagagg gacccagtaa gaccaaagga ggggaggaca   1860

gagcatgaaa accaaaatcc atgcaaatga aatgtaattg gcacgaccct cacccccaaa   1920

tcttacatct caattcccat cctaaaaagc actcatactt tatgcatccc cgcagctaca   1980

cacacacaac acacagcaca cgcatgaaca cagcacacac acgagcacag cacacacaca   2040

aacgcacagc acacacagca cacagatgag cacacagcac acacacaaac gcacagcaca   2100

cacacgcaca cacatgcaca cacagcacac aaacgcacgg cacacacacg cacacacatg   2160

cacacacagc acacacacaa acgcacagca cacacaaacg cacagcacac acgcacacac   2220

agcacacaca cgagcacaca gcacacaaac gcacagcaca cgcacacaca tgcacacaca   2280

gcacacacac tagcacacag cacacacaca aagacacagc acacacatgc acacacagca   2340

cacacacgcg aacacagcac acacgaacac agcacacaca gcacacacac aaacacagca   2400

cacacatgca cacagcacac gcacacacag cacacacatg aacacagcac acagcacaca   2460

catgcacaca cagcacacac gcatgcacag cacacatgaa cacagcacac acacaaacac   2520

acagcacaca catgcacaca cagcacacac actcatgcgc agcacataca tgaacacagc   2580

tcacagcaca caaacacgca gcacacacgt tgcacacgca agcacccacc tgcacacaca   2640

catgcgcaca cacacgcaca cccccacaaa attggatgaa aacaataagc atatctaagc   2700

aactacgata tctgtatgga tcaggccaaa gtcccgctaa gattctccaa tgttttcatg   2760

gtctgagccc cgctcctgtt cccatctcca ctgcccctcg gccctgtctg tgccctgcct   2820

ctcagaggag ggggctcaga tggtgcggcc tgagtgtgcg gccggcggca tttgggatac   2880

acccgtaggg tgggcggggt gtgtcccagg cctaattcca tctttccacc atgacagaga   2940

tgcccttgtg aggctggcct ccttggcgcc tgtccccacg gcccccgcag cgtgagccac   3000

gatgctcccc ataccccacc cattcccgat acaccttact tactgtgtgt tggcccagcc   3060

agagtgagga aggagtttgg ccacattgga gatggcggta gctgagcaga catgccccca   3120

cgagtagcct gactccctgg tgtgctcctg gaaggaagat cttggggacc cccccaccgg   3180

agcacaccta gggatcatct ttgcccgtct cctggggacc ccccaagaaa tgtggagtcc   3240

tcgggggccg tgcactgatg cggggagtgt gggaagtctg gcggttggag gggtgggtgg   3300

ggggcagtgg gggctgggcg gggggagttc tggggtagga agtggtcccg ggagattttg   3360

gatggaaaag tcaggaggat tgacagcaga cttgcagaat tacatagaga aattaggaac   3420

ccccaaattt catgtcaatt gatctattcc ccctctttgt ttcttggggc atttttcctt   3480

tttttttttt ttttgttttt tttttacccc tccttagctt tatgcgctca gaaaccaaat   3540

taaacccccc ccccatgtaa caggggggca gtgacaaaag caagaacgca cgaagccagc   3600

ctggagacca ccacgtcctg ccccccgcca tttatcgccc tgattggatt ttgtttttca   3660

tctgtccctg ttgcttgggt tgagttgagg gtggagcctc ctggggggca ctggccactg   3720

agcccccttg gagaagtcag aggggagtgg agaaggccac tgtccggcct ggcttctggg   3780

gacagtggct ggtccccaga agtcctgagg gcggaggggg gggttgggca gggtctcctc   3840

aggtgtcagg agggtgctcg gaggccacag gagggggctc ctggctggcc tgaggctggc   3900

cggaggggaa ggggctagca ggtgtgtaaa cagagggttc catcaggctg gggcagggtg   3960

gccgccttcc gcacacttga ggaaccctcc cctctccctc ggtgacatct tgcccgcccc   4020

tcagcaccct gccttgtctc caggaggtcc gaagctctgt gggacctctt gggggcaagg   4080

tggggtgagg ccggggagta gggaggtcag gcgggtctga gcccacagag caggagagct   4140

gccaggtctg cccatcgacc aggttgcttg ggccccggag cccacgggtc tggtgatgcc   4200

atagcagcca ccaccgcggc gcctagggct gcggcaggga ctcggcctct gggaggttta   4260

cctcgccccc acttgtgccc ccagctcagc ccccctgcac gcagcccgac tagcagtcta   4320

gaggcctgag gcttctgggt cctggtgacg gggctggcat gaccccgggg gtcgtccatg   4380

ccagtccgcc tcagtcgcag agggtccctc ggcaagcgcc ctgtgagtgg gccattcgga   4440

acattggaca gaagcccaaa gagccaaatt gtcacaattg tggaacccac attggcctga   4500

gatccaaaac gcttcgaggc accccaaatt acctgcccat tcgtcaggac acccacccac   4560

ccagtgttat attctgcctc gccggagtgg gtgttcccgg gggcacttgc cgaccagccc   4620

cttgcgtccc caggtttgca gctctcccct gggccactaa ccatcctggc ccgggctgcc   4680

tgtctgacct ccgtgcctag tcgtggctct ccatcttgtc tcctccccgt gtccccaatg   4740

tcttcagtgg ggggccccct cttgggtccc ctcctctgcc atcacctgaa gacccccacg   4800

ccaaacactg aatgtcacct gtgcctgccg cctcggtcca ccttgcggcc cgtgtttgac   4860

tcaactcaac tcctttaacg ctaatatttc cggcaaaatc ccatgcttgg gttttgtctt   4920

taaccttgta acgcttgcaa tcccaataaa gcattaaaag tcatgatctt c            4971


<210>  7721
<211>  236
<212>  PRT
<213>  Homo sapiens

<400>  7721

Met Val Ser Pro Asp Pro Gln Ile Ile Val Val Ala Pro Glu Thr Glu 
1               5                   10                  15


Leu Ala Ser Met Gln Val Gln Arg Thr Glu Asp Gly Val Thr Ile Ile 
            20                  25                  30


Gln Ile Phe Trp Val Gly Arg Lys Gly Glu Leu Leu Arg Arg Thr Pro 
        35                  40                  45


Val Ser Ser Ala Met Gln Thr Pro Met Gly Ile Pro Met Gly Lys Ser 
    50                  55                  60


Met Leu Val Leu Leu Thr Phe Leu Ala Phe Ala Ser Cys Cys Ile Ala 
65                  70                  75                  80


Ala Tyr Arg Pro Ser Glu Thr Leu Cys Gly Gly Glu Leu Val Asp Thr 
                85                  90                  95


Leu Gln Phe Val Cys Gly Asp Arg Gly Phe Tyr Phe Ser Arg Pro Ala 
            100                 105                 110


Ser Arg Val Ser Arg Arg Ser Arg Gly Ile Val Glu Glu Cys Cys Phe 
        115                 120                 125


Arg Ser Cys Asp Leu Ala Leu Leu Glu Thr Tyr Cys Ala Thr Pro Ala 
    130                 135                 140


Lys Ser Glu Arg Asp Val Ser Thr Pro Pro Thr Val Leu Pro Asp Asn 
145                 150                 155                 160


Phe Pro Arg Tyr Pro Val Gly Lys Phe Phe Gln Tyr Asp Thr Trp Lys 
                165                 170                 175


Gln Ser Thr Gln Arg Leu Arg Arg Gly Leu Pro Ala Leu Leu Arg Ala 
            180                 185                 190


Arg Arg Gly His Val Leu Ala Lys Glu Leu Glu Ala Phe Arg Glu Ala 
        195                 200                 205


Lys Arg His Arg Pro Leu Ile Ala Leu Pro Thr Gln Asp Pro Ala His 
    210                 215                 220


Gly Gly Ala Pro Pro Glu Met Ala Ser Asn Arg Lys 
225                 230                 235


<210>  7722
<211>  1324
<212>  DNA
<213>  Homo sapiens

<400>  7722
tcatgacttt taatgcttta ttgggattgc aagcgttaca aggttaaaga caaaacccaa     60

gcatgggatt ttgccggaaa tattagcgtt aaaggagttg agttgagtca aacacgggcc    120

gcaaggtgga ccgaggcggc aggcacaggt gacattcagt gtttggcctc tttgggcttc    180

tgtccaatgt tccgaatggc ccactcacag ggcgcttgcc gagggaccct ctgcgactga    240

ggcggactgg catggacgac ccccggggtc atgccagccc cgtcaccagg acccagaagc    300

ctcaggcctc tagactgcta gtcgggctgc gtgcaggggg gctgagctgg gggcacaagt    360

gggggcgagg taaacctccc agaggccgag tccctgccgc agccctaggc gccgcggtgg    420

tggctgctat ggcatcacca gacccgtggg ctccggggcc caagcaacct ggtcgatggg    480

cagacctggc agctctcctg ctctgtgggc tcagacccgc ctgacctccc tactccccgg    540

cctcacccca ccttgccccc aagaggtccc acagagcttc ggacctcctg gagacaaggc    600

agggtgctga ggggcgggca agatgtcacc gagggagagg ggagggttcc tcaagtgtgc    660

ggaaggcggc caccctgccc cagcctgatg gaaccctctg tttacacacc tgctagcccc    720

ttcccctccg gccagcctca ggccagccag gagccccctc ctgtggcctc cgagcaccct    780

cctgacacct gaggagaccc tgcccaaccc ccccctccgc cctcaggact tctggggacc    840

agccactgtc cccagaagcc aggccggaca gtggccttct ccactcccct ctgacttctc    900

caagggggct cagtggccag tgccccccag gaggctccac cctcaactca acccaagcaa    960

cagggacaga tgaaaaacaa aatccaatca gggcgataaa tggcgggggg caggacgtgg   1020

tggtctccag gctggcttcg tgcgttcttg cttttgtcac tgcccccctg ttacatgggg   1080

ggggggttta atttggtttc tgagcgcata aagctaagga ggggtaaaaa aaaaacaaaa   1140

aaaaaaaaaa aaggaaaaat gccccaagaa acaaagaggg ggaatagatc aattgacatg   1200

aaatttgggg gttcctaatt tctctatgta attctgcaag tctgctgtca atcctcctga   1260

cttttccatc caaaatctcc cgggaccact tcctacccca gaactccccc cgcccagccc   1320

ccac                                                                1324


<210>  7723
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  7723

Met Leu Tyr Trp Asp Cys Lys Arg Tyr Lys Val Lys Asp Lys Thr Gln 
1               5                   10                  15


Ala Trp Asp Phe Ala Gly Asn Ile Ser Val Lys Gly Val Glu Leu Ser 
            20                  25                  30


Gln Thr Arg Ala Ala Arg Trp Thr Glu Ala Ala Gly Thr Gly Asp Ile 
        35                  40                  45


Gln Cys Leu Ala Ser Leu Gly Phe Cys Pro Met Phe Arg Met Ala His 
    50                  55                  60


Ser Gln Gly Ala Cys Arg Gly Thr Leu Cys Asp 
65                  70                  75


<210>  7724
<211>  965
<212>  DNA
<213>  Homo sapiens

<400>  7724
tcatgacttt taatgcttta ttgggattgc aagcgttaca aggttaaaga caaaacccaa     60

gcatgggatt ttgccggaaa tattagcgtt aaaggagttg agttgagtca aacacgggcc    120

gcaaggtgga ccgaggcggc aggcacaggt gacattcagt gtttggcgtg ggggtcttca    180

ggtgatggca gaggagggga cccaagaggg ggccccccac tgaagacatt ggggacacgg    240

ggaggagaca agatggagag ccacgactag gcacggaggt cagacaggca gcccgggcca    300

ggatggttag tggcccaggg gagagctgca aacctgggga cgcaaggggc tggtcggcaa    360

gtgcccccgg gaacacccac tccggcgagg cagaatataa cactgggtgg gtgggtgtcc    420

tgacgaatgg gcaggtaatt tggggtgcct cgaagcgttt tggatctcag gccaatgtgg    480

gttccacaat tgtgacaatt tggctctttg ggcttctgtc caatgttccg aatggcccac    540

tcacagggcg cttgccgagg gaccctctgc gactgaggcg gactggcatg gacgaccccc    600

ggggtcatgc cagccccgtc accaggaccc agaagcctca ggcctctaga ctgctagtcg    660

ggctgcgtgc aggggggttc gtgcgttctt gcttttgtca ctgcccccct gttacatggg    720

gggggggttt aatttggttt ctgagcgcat aaagctaagg aggggtaaaa aaaaaacaaa    780

aaaaaaaaaa aaaggaaaaa tgccccaaga aacaaagagg gggaatagat caattgacat    840

gaaatttggg ggttcctaat ttctctatgt aattctgcaa gtctgctgtc aatcctcctg    900

acttttccat ccaaaatctc ccgggaccac ttcctacccc agaactcccc ccgcccagcc    960

cccac                                                                965


<210>  7725
<211>  149
<212>  PRT
<213>  Homo sapiens

<400>  7725

Met Val Ser Gly Pro Gly Glu Ser Cys Lys Pro Gly Asp Ala Arg Gly 
1               5                   10                  15


Trp Ser Ala Ser Ala Pro Gly Asn Thr His Ser Gly Glu Ala Glu Tyr 
            20                  25                  30


Asn Thr Gly Trp Val Gly Val Leu Thr Asn Gly Gln Val Ile Trp Gly 
        35                  40                  45


Ala Ser Lys Arg Phe Gly Ser Gln Ala Asn Val Gly Ser Thr Ile Val 
    50                  55                  60


Thr Ile Trp Leu Phe Gly Leu Leu Ser Asn Val Pro Asn Gly Pro Leu 
65                  70                  75                  80


Thr Gly Arg Leu Pro Arg Asp Pro Leu Arg Leu Arg Arg Thr Gly Met 
                85                  90                  95


Asp Asp Pro Arg Gly His Ala Ser Pro Val Thr Arg Thr Gln Lys Pro 
            100                 105                 110


Gln Ala Ser Arg Leu Leu Val Gly Leu Arg Ala Gly Gly Phe Val Arg 
        115                 120                 125


Ser Cys Phe Cys His Cys Pro Pro Val Thr Trp Gly Gly Gly Leu Ile 
    130                 135                 140


Trp Phe Leu Ser Ala 
145


<210>  7726
<211>  498
<212>  DNA
<213>  Homo sapiens

<400>  7726
tcatgacttt taatgcttta ttgggattgc aagcgttaca aggttaaaga caaaacccaa     60

gcatgggatt ttgccggaaa tattagcgtt aaaggagttg agttgagtca aacacgggcc    120

gcaaggtgga ccgaggcggc aggcacaggt gacattcagt gtttggcgtg ggggtcttca    180

ggtgatggca gaggagggga cccaagaggg ggccccccac tgaagacatt ggagaatctt    240

agcgggactt tggcctgatc catacagata tcgtagttgc ttagatatgc ttattgtttt    300

catccaattt tgtgggggtg tgcgtgtgtg tgcgcatgtg tgtgtgcagg tgggtgcttg    360

cgtgtgcaac gtgtgtgctg cgtgtttgtg tgctgtgagc tgtgttcatg tatgtgctgc    420

gcatgagtgt gtgtgctgtg tgtgcatgtg tgtgctgtgt gtttgtgtgt gtgctgtgtt    480

catgtgtgct gtgcatgc                                                  498


<210>  7727
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  7727

Met Leu Tyr Trp Asp Cys Lys Arg Tyr Lys Val Lys Asp Lys Thr Gln 
1               5                   10                  15


Ala Trp Asp Phe Ala Gly Asn Ile Ser Val Lys Gly Val Glu Leu Ser 
            20                  25                  30


Gln Thr Arg Ala Ala Arg Trp Thr Glu Ala Ala Gly Thr Gly Asp Ile 
        35                  40                  45


Gln Cys Leu Ala Trp Gly Ser Ser Gly Asp Gly Arg Gly Gly Asp Pro 
    50                  55                  60


Arg Gly Gly Pro Pro Leu Lys Thr Leu Glu Asn Leu Ser Gly Thr Leu 
65                  70                  75                  80


Ala 



<210>  7728
<211>  2619
<212>  DNA
<213>  Homo sapiens

<400>  7728
gcgaacacag cacacacgaa cacagcacac acagcacaca cacaaacaca gcacacacat     60

gcacacagca cacgcacaca cagcacacac atgaacacag cacacagcac acacatgcac    120

acacagcaca cacgcatgca cagcacacat gaacacagca cacacacaaa cacacagcac    180

acacatgcac acacagcaca cacactcatg cgcagcacat acatgaacac agctcacagc    240

acacaaacac gcagcacaca cgttgcacac gcaagcaccc acctgcacac acacatgcgc    300

acacacacgc acacccccac aaaattggat gaaaacaata agcatatcta agcaactacg    360

atatctgtat ggatcaggcc aaagtcccgc taagattctc caatgttttc atggtctgag    420

ccccgctcct gttcccatct ccactgcccc tcggccctgt ctgtgccctg cctctcagag    480

gagggggctc agatggtgcg gcctgagtgt gcggccggcg gcatttggga tacacccgta    540

gggtgggcgg ggtgtgtccc aggcctaatt ccatctttcc accatgacag agatgccctt    600

gtgaggctgg cctccttggc gcctgtcccc acggcccccg cagcgtgagc cacgatgctc    660

cccatacccc acccattccc gatacacctt acttactgtg tgttggccca gccagagtga    720

ggaaggagtt tggccacatt ggagatggcg gtagctgagc agacatgccc ccacgagtag    780

cctgactccc tggtgtgctc ctggaaggaa gatcttgggg acccccccac cggagcacac    840

ctagggatca tctttgcccg tctcctgggg accccccaag aaatgtggag tcctcggggg    900

ccgtgcactg atgcggggag tgtgggaagt ctggcggttg gaggggtggg tggggggcag    960

tgggggctgg gcggggggag ttctggggta ggaagtggtc ccgggagatt ttggatggaa   1020

aagtcaggag gattgacagc agacttgcag aattacatag agaaattagg aacccccaaa   1080

tttcatgtca attgatctat tccccctctt tgtttcttgg ggcatttttc cttttttttt   1140

tttttttgtt ttttttttac ccctccttag ctttatgcgc tcagaaacca aattaaaccc   1200

cccccccatg taacaggggg gcagtgacaa aagcaagaac gcacgaagcc agcctggaga   1260

ccaccacgtc ctgccccccg ccatttatcg ccctgattgg attttgtttt tcatctgtcc   1320

ctgttgcttg ggttgagttg agggtggagc ctcctggggg gcactggcca ctgagccccc   1380

ttggagaagt cagaggggag tggagaaggc cactgtccgg cctggcttct ggggacagtg   1440

gctggtcccc agaagtcctg agggcggagg ggggggttgg gcagggtctc ctcaggtgtc   1500

aggagggtgc tcggaggcca caggaggggg ctcctggctg gcctgaggct ggccggaggg   1560

gaaggggcta gcaggtgtgt aaacagaggg ttccatcagg ctggggcagg gtggccgcct   1620

tccgcacact tgaggaaccc tcccctctcc ctcggtgaca tcttgcccgc ccctcagcac   1680

cctgccttgt ctccaggagg tccgaagctc tgtgggacct cttgggggca aggtggggtg   1740

aggccgggga gtagggaggt caggcgggtc tgagcccaca gagcaggaga gctgccaggt   1800

ctgcccatcg accaggttgc ttgggccccg gagcccacgg gtctggtgat gccatagcag   1860

ccaccaccgc ggcgcctagg gctgcggcag ggactcggcc tctgggaggt ttacctcgcc   1920

cccacttgtg cccccagctc agcccccctg cacgcagccc gactagcagt ctagaggcct   1980

gaggcttctg ggtcctggtg acggggctgg catgaccccg ggggtcgtcc atgccagtcc   2040

gcctcagtcg cagagggtcc ctcggcaagc gccctgtgag tgggccattc ggaacattgg   2100

acagaagccc aaagagccaa attgtcacaa ttgtggaacc cacattggcc tgagatccaa   2160

aacgcttcga ggcaccccaa attacctgcc cattcgtcag gacacccacc cacccagtgt   2220

tatattctgc ctcgccggag tgggtgttcc cgggggcact tgccgaccag ccccttgcgt   2280

ccccaggttt gcagctctcc cctgggccac taaccatcct ggcccgggct gcctgtctga   2340

cctccgtgcc tagtcgtggc tctccatctt gtctcctccc cgtgtcccca atgtcttcag   2400

tggggggccc cctcttgggt cccctcctct gccatcacct gaagaccccc acgccaaaca   2460

ctgaatgtca cctgtgcctg ccgcctcggt ccaccttgcg gcccgtgttt gactcaactc   2520

aactccttta acgctaatat ttccggcaaa atcccatgct tgggttttgt ctttaacctt   2580

gtaacgcttg caatcccaat aaagcattaa aagtcatga                          2619


<210>  7729
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  7729

Met Thr Pro Gly Val Val His Ala Ser Pro Pro Gln Ser Gln Arg Val 
1               5                   10                  15


Pro Arg Gln Ala Pro Cys Glu Trp Ala Ile Arg Asn Ile Gly Gln Lys 
            20                  25                  30


Pro Lys Glu Pro Asn Cys His Asn Cys Gly Thr His Ile Gly Leu Arg 
        35                  40                  45


Ser Lys Thr Leu Arg Gly Thr Pro Asn Tyr Leu Pro Ile Arg Gln Asp 
    50                  55                  60


Thr His Pro Pro Ser Val Ile Phe Cys Leu Ala Gly Val Gly Val Pro 
65                  70                  75                  80


Gly Gly Thr Cys Arg Pro Ala Pro Cys Val Pro Arg Phe Ala Ala Leu 
                85                  90                  95


Pro Trp Ala Thr Asn His Pro Gly Pro Gly Cys Leu Ser Asp Leu Arg 
            100                 105                 110


Ala 



<210>  7730
<211>  1050
<212>  DNA
<213>  Homo sapiens

<400>  7730
aatgtgggtt ccacaattgt gacaatttgg ctctttgggc ttctgtccaa tgttccgaat     60

ggcccactca cagggcgctt gccgagggac cctctgcgac tgaggcggac tggcatggac    120

gacccccggg gtcatgccag ccccgtcacc aggacccaga agcctcaggc ctctagactg    180

ctagtcgggc tgcgtgcagg ggggctgagc tgggggcaca agtgggggcg aggtaaacct    240

cccagaggcc gagtccctgc cgcagcccta ggcgccgcgg tggtggctgc tatggcatca    300

ccagacccgt gggctccggg gcccaagcaa cctggtcgat gggcagacct ggcagctctc    360

ctgctctgtg ggctcagacc cgcctgacct ccctactccc cggcctcacc ccaccttgcc    420

cccaagaggt cccacagagc ttcggacctc ctggagacaa ggcagggtgc tgaggggcgg    480

gcaagatgtc accgagggag aggggagggt tcctcaagtg tgcggaaggc ggccaccctg    540

ccccagcctg atggaaccct ctgtttacac acctgctagc cccttcccct ccggccagcc    600

tcaggccagc caggagcccc ctcctgtggc ctccgagcac cctcctgaca cctgaggagg    660

ctccaccctc aactcaaccc aagcaacagg gacagatgaa aaacaaaatc caatcagggc    720

gataaatggc ggggggcagg acgtggtggt ctccaggctg gcttcgtgcg ttcttgcttt    780

tgtcactgcc cccctgttac atgggggggg ggtttaattt ggtttctgag cgcataaagc    840

taaggagggg taaaaaaaaa acaaaaaaaa aaaaaaaagg aaaaatgccc caagaaacaa    900

agagggggaa tagatcaatt gacatgaaat ttgggggttc ctaatttctc tatgtaattc    960

tgcaagtctg ctgtcaatcc tcctgacttt tccatccaaa atctcccggg accacttcct   1020

accccagaac tccccccgcc cagcccccac                                    1050


<210>  7731
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7731

Met Asp Asp Pro Arg Gly His Ala Ser Pro Val Thr Arg Thr Gln Lys 
1               5                   10                  15


Pro Gln Ala Ser Arg Leu Leu Val Gly Leu Arg Ala Gly Gly Leu Ser 
            20                  25                  30


Trp Gly His Lys Trp Gly Arg Gly Lys Pro Pro Arg Gly Arg Val Pro 
        35                  40                  45


Ala Ala Ala Leu Gly Ala Ala Val Val Ala Ala Met Ala Ser Pro Asp 
    50                  55                  60


Pro Trp Ala Pro Gly Pro Lys Gln Pro Gly Arg Trp Ala Asp Leu Ala 
65                  70                  75                  80


Ala Leu Leu Leu Cys Gly Leu Arg Pro Ala 
                85                  90


<210>  7732
<211>  1084
<212>  DNA
<213>  Homo sapiens

<400>  7732
aatgtgggtt ccacaattgt gacaatttgg ctctttgggc ttctgtccaa tgttccgaat     60

ggcccactca cagggcgctt gccgagggac cctctgcgac tgaggcggac tggcatggac    120

gacccccggg gtcatgccag ccccgtcacc aggacccaga agcctcaggc ctctagactg    180

ctagtcgggc tgcgtgcagg ggggctgagc tgggggcaca agtgggggcg aggtaaacct    240

cccagaggcc gagtccctgc cgcagcccta ggcgccgcgg tggtggctgc tatggcatca    300

ccagacccgt gggctccggg gcccaagcaa cctggtcgat gggcagacct ggcagctctc    360

ctgctctgtg ggctcagacc cgcctgacct ccctactccc cggcctcacc ccaccttgcc    420

cccaagaggt cccacagagc ttcggacctc ctggagacaa ggcagggtgc tgaggggcgg    480

gcaagatgtc accgagggag aggggagggt tcctcaagtg tgcggaaggc ggccacccct    540

cctgacacct gaggagaccc tgcccaaccc ccccctccgc cctcaggact tctggggacc    600

agccactgtc cccagaagcc aggccggaca gtggccttct ccactcccct ctgacttctc    660

caagggggct cagtggccag tgccccccag gaggctccac cctcaactca acccaagcaa    720

cagggacaga tgaaaaacaa aatccaatca gggcgataaa tggcgggggg caggacgtgg    780

tggtctccag gctggcttcg tgcgttcttg cttttgtcac tgcccccctg ttacatgggg    840

ggggggttta atttggtttc tgagcgcata aagctaagga ggggtaaaaa aaaaacaaaa    900

aaaaaaaaaa aaggaaaaat gccccaagaa acaaagaggg ggaatagatc aattgacatg    960

aaatttgggg gttcctaatt tctctatgta attctgcaag tctgctgtca atcctcctga   1020

cttttccatc caaaatctcc cgggaccact tcctacccca gaactccccc cgcccagccc   1080

ccac                                                                1084


<210>  7733
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  7733

Met Asp Asp Pro Arg Gly His Ala Ser Pro Val Thr Arg Thr Gln Lys 
1               5                   10                  15


Pro Gln Ala Ser Arg Leu Leu Val Gly Leu Arg Ala Gly Gly Leu Ser 
            20                  25                  30


Trp Gly His Lys Trp Gly Arg Gly Lys Pro Pro Arg Gly Arg Val Pro 
        35                  40                  45


Ala Ala Ala Leu Gly Ala Ala Val Val Ala Ala Met Ala Ser Pro Asp 
    50                  55                  60


Pro Trp Ala Pro Gly Pro Lys Gln Pro Gly Arg Trp Ala Asp Leu Ala 
65                  70                  75                  80


Ala Leu Leu Leu Cys Gly Leu Arg Pro Ala 
                85                  90


<210>  7734
<211>  462
<212>  DNA
<213>  Homo sapiens

<400>  7734
tggagacaag gcagggtgct gaggggcggg caagatgtca ccgagggaga ggggagggtt     60

cctcaagtgt gcggaaggcg gccaccctgc cccagcctga tggaaccctc tgtttacaca    120

cctgctagcc ccttcccctc cggccagcct caggccagcc aggagccccc tcctgtggcc    180

tccgagcacc ctcctgacac ctgaggagac cctgcccaac ccccccctcc gccctcagga    240

cttctgggga ccagccactg tccccagaag ccaggccgga cagtggcctt ctccactccc    300

ctctgacttc tccaaggggg ctcagtggcc agtgcccccc aggaggctcc accctcaact    360

caacccaagc aacagggaca gatgaaaaac aaaatccaat cagggcgata aatggggggg    420

gggtttaatt tggtttctga gcgcataaag ctaaggaggg gt                       462


<210>  7735
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  7735

Met Glu Pro Ser Val Tyr Thr Pro Ala Ser Pro Phe Pro Ser Gly Gln 
1               5                   10                  15


Pro Gln Ala Ser Gln Glu Pro Pro Pro Val Ala Ser Glu His Pro Pro 
            20                  25                  30


Asp Thr 



<210>  7736
<211>  952
<212>  DNA
<213>  Homo sapiens

<400>  7736
actccacatt tcttgggggg tccccaggag acgggcaaag atgatcccta ggtgtgctcc     60

ggtggggggg tccccaagat cttccttcca ggagcacacc agggagtcag gctactcgtg    120

ggggcatgtc tgctcagcta ccgccatctg tgatttctgg ggtccttctt ttctctttgc    180

tggttcaggg actcaagtcc aggccaattt gactcaaagt ccaagggaga agagaaagag    240

gggggtgggg agtgccaaat tcctttattt tgccaattgt ttctcagcca attcgttttt    300

aatacttttt ttttttagcc aattgatttt ttttggtggt tgtttttttt aaagccaatt    360

tctgagcttt tgtggggtgt ttctaaaaag ccaattagtt ttaagagggt tgttgtgggg    420

gggggggaag ggggttagtt taatgttttg attttttatg tgtggggata attggggata    480

atttgggggg agggtatgtg aagggtgttt aaagccaatc gattttgtac atgtttgaag    540

atgctgctgt gcttcctcag cccgatggag ggggccgagg agagtagcct gtttcgggga    600

ggcggggcac ggggactggg tcaggagaag ccccaggggg acgtggaacc gagagatttt    660

cgggatggaa cctgatggaa acgtccgtgg tcaggaggag gctgcaggat ggtggcgccg    720

ggctgcagac ttgcggcagt tttgctcact tccgattgct ggccatctct gggggggcgc    780

ccccgtgggc ggggtcttgg gtgggtagag caatcagggg acggtgacgt ttggcctccc    840

tgaacgcctc gagctccttg gcgagcacgt gaccccggcg ggcacgcagg agggcaggca    900

ggcccctgcg caggcgctgg gtggactgct tccaggtgtc atattggaag aa            952


<210>  7737
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  7737

Met Ile Pro Arg Cys Ala Pro Val Gly Gly Ser Pro Arg Ser Ser Phe 
1               5                   10                  15


Gln Glu His Thr Arg Glu Ser Gly Tyr Ser Trp Gly His Val Cys Ser 
            20                  25                  30


Ala Thr Ala Ile Cys Asp Phe Trp Gly Pro Ser Phe Leu Phe Ala Gly 
        35                  40                  45


Ser Gly Thr Gln Val Gln Ala Asn Leu Thr Gln Ser Pro Arg Glu Lys 
    50                  55                  60


Arg Lys Arg Gly Val Gly Ser Ala Lys Phe Leu Tyr Phe Ala Asn Cys 
65                  70                  75                  80


Phe Ser Ala Asn Ser Phe Leu Ile Leu Phe Phe Phe Ser Gln Leu Ile 
                85                  90                  95


Phe Phe Gly Gly Cys Phe Phe 
            100


<210>  7738
<211>  450
<212>  DNA
<213>  Homo sapiens

<400>  7738
taccgccatc tccaatgtgg ccaaactcct tcctcactct ggctgggcca acacacagta     60

agtaaggtgt atcgggaatg ggtggggtat ggggagcatc gtggctcacg ctgcgggggc    120

cgtggggaca ggcgccaagg aggccagcct cacaagggca tctctgtcat ggtggaaaga    180

tggaattagg cctgggacac accccgccca ccctacgggt gtatcccaaa tgccgccggc    240

cgcacactca ggccgcacca tctgagcccc ctcctctgag aggcagggca cagacagggc    300

cgaggggcag tggagatggg aacaggagcg gggtgtgcgt gtgtgtgcgc atgtgtgtgt    360

gcaggtgggt gcttgcgtgt gcaacgtgtg tgctgcgtgt ttgtgtgctg tgagctgtgt    420

tcatgtatgt gctgcgcatg agtgtgtgtg                                     450


<210>  7739
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  7739

Met Gly Gly Val Trp Gly Ala Ser Trp Leu Thr Leu Arg Gly Pro Trp 
1               5                   10                  15


Gly Gln Ala Pro Arg Arg Pro Ala Ser Gln Gly His Leu Cys His Gly 
            20                  25                  30


Gly Lys Met Glu Leu Gly Leu Gly His Thr Pro Pro Thr Leu Arg Val 
        35                  40                  45


Tyr Pro Lys Cys Arg Arg Pro His Thr Gln Ala Ala Pro Ser Glu Pro 
    50                  55                  60


Pro Pro Leu Arg Gly Arg Ala Gln Thr Gly Pro Arg Gly Ser Gly Asp 
65                  70                  75                  80


Gly Asn Arg Ser Gly Val Cys Val Cys Val Arg Met Cys Val Cys Arg 
                85                  90                  95


Trp Val Leu Ala Cys Ala Thr Cys Val Leu Arg Val Cys Val Leu 
            100                 105                 110


<210>  7740
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  7740
gggccaacac acagtaagta aggtgtatcg ggaatgggtg gggtatgggg agcatcgtgg     60

ctcacgccta cgggtgtatc ccaaatgccg ccggccgcac actcaggccg caccatctga    120

gccccctcct ctgagaggca gggcacagac agggccgagg ggcagtggag atgggaacag    180

gagcggggct cagaccatga aaacattgga gaatcttagc gggactttgg cctgatccat    240

acagatatcg tagttgctta gatatgctta ttgttttcat ccaattttgt gggggtgtgc    300

gtgtgtgtgc gcatgtgtgt gtgcaggtgg gtgcttgcgt gtgcaacgtg tgtgctgcgt    360

gtttgtgtgc tgtgagctgt gttcatgtat gtgctgcgca tgagtgtgtg tgctgtgtgt    420

gcatgtgtgt gctgtgtgtt tgtgtgtgtg ctgtgttcat gtgtgctgtg catgcgtgtg    480

tgctgtgtgt gcatgtgtgt gctgtgtgct gtgttcatgt gtgtgctgtg tgtgcgtgtg    540

ctgtgtg                                                              547


<210>  7741
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  7741

Met Leu Ile Val Phe Ile Gln Phe Cys Gly Gly Val Arg Val Cys Ala 
1               5                   10                  15


His Val Cys Val Gln Val Gly Ala Cys Val Cys Asn Val Cys Ala Ala 
            20                  25                  30


Cys Leu Cys Ala Val Ser Cys Val His Val Cys Ala Ala His Glu Cys 
        35                  40                  45


Val Cys Cys Val Cys Met Cys Val Leu Cys Val Cys Val Cys Ala Val 
    50                  55                  60


Phe Met Cys Ala Val His Ala Cys Val Leu Cys Val His Val Cys Ala 
65                  70                  75                  80


Val Cys Cys Val His Val Cys Ala Val Cys Ala Cys Ala 
                85                  90


<210>  7742
<211>  1029
<212>  DNA
<213>  Homo sapiens

<400>  7742
aactggacat tagcttctcc tgtgaaagag acttccagct tcctcctcct cctcttcctc     60

ctcctcctcc tgccccagcg agccttctgc tgagctacac caatgggaat cccaatgggg    120

aagtcgatgc tggtgcttct caccttcttg gccttcgcct cgtgctgcat tgctgcttac    180

cgccccagtg agaccctgtg cggcggggag ctggtggaca ccctccagtt cgtctgtggg    240

gaccgcggct tctacttcag caggcccgca agccgtgtga gccgtcgcag ccgtggcatc    300

gttgaggagt gctgtttccg cagctgtgac ctggccctcc tggagacgta ctgtgctacc    360

cccgacaact tccccagata ccccgtgggc aagttcttcc aatatgacac ctggaagcag    420

tccacccagc gcctgcgcag gggcctgcct gccctcctgc gtgcccgccg gggtcacgtg    480

ctcgccaagg agctcgaggc gttcagggag gccaaacgtc accgtcccct gattgctcta    540

cccacccaag accccgccca cgggggcgcc cccccagaga tggccagcaa tcggaagtga    600

gcaaaactgc cgcaagtctg cagcccggcg ccaccatcct gcagcctcct cctgaccacg    660

gacgtttcca tcaggttcca tcccgaaaat ctctcggttc cacgtccccc tggggcttct    720

cctgacccag tccccgtgcc ccgcctcccc gaaacaggct actctcctcg gccccctcca    780

tcgggctgag gaagcacagc agcatcttca aacatgtaca aaatcgattg gctttaaaca    840

cccttcacat accctccccc caaattatcc ccaattatcc ccacacataa aaaatcaaaa    900

cattaaacta acccccttcc ccccccccca caacaaccct cttaaaacta attggctttt    960

tagaaacacc ccacaaaagc tcagaaattg gctttaaaaa aaacaaccac caaaaaaaat   1020

caattggct                                                           1029


<210>  7743
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  7743

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly 
                85                  90                  95


Lys Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg 
            100                 105                 110


Arg Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala 
        115                 120                 125


Lys Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile 
    130                 135                 140


Ala Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met 
145                 150                 155                 160


Ala Ser Asn Arg Lys 
                165


<210>  7744
<211>  1092
<212>  DNA
<213>  Homo sapiens

<400>  7744
ggcactgacc agcctgcaaa ctggacatta gcttctcctg tgaaagagac ttccagcttc     60

ctcctcctcc tcttcctcct cctcctcctg ccccagcgag ccttctgctg agctacacca    120

atgggaatcc caatggggaa gtcgatgctg gtgcttctca ccttcttggc cttcgcctcg    180

tgctgcattg ctgcttaccg ccccagtgag accctgtgcg gcggggagct ggtggacacc    240

ctccagttcg tctgtgggga ccgcggcttc tacttcagca ggcccgcaag ccgtgtgagc    300

cgtcgcagcc gtggcatcgt tgaggagtgc tgtttccgca gctgtgacct ggccctcctg    360

gagacgtact gtgctacccc cgccaagtcc gagagggacg tgtcgacccc tccgaccgtg    420

cttccggaca acttccccag ataccccgtg ggcaagttct tccaatatga cacctggaag    480

cagtccaccc agcgcctgcg caggggcctg cctgccctcc tgcgtgcccg ccggggtcac    540

gtgctcgcca aggagctcga ggcgttcagg gaggccaaac gtcaccgtcc cctgattgct    600

ctacccaccc aagaccccgc ccacgggggc gcccccccag agatggccag caatcggaag    660

tgagcaaaac tgccgcaagt ctgcagcccg gcgccaccat cctgcagcct cctcctgacc    720

acggacgttt ccatcaggtt ccatcccgaa aatctctcgg ttccacgtcc ccctggggct    780

tctcctgacc cagtccccgt gccccgcctc cccgaaacag gctactctcc tcggccccct    840

ccatcgggct gaggaagcac agcagcatct tcaaacatgt acaaaatcga ttggctttaa    900

acacccttca cataccctcc ccccaaatta tccccaatta tccccacaca taaaaaatca    960

aaacattaaa ctaaccccct tccccccccc ccacaacaac cctcttaaaa ctaattggct   1020

ttttagaaac accccacaaa agctcagaaa ttggctttaa aaaaaacaac caccaaaaaa   1080

aatcaattgg ct                                                       1092


<210>  7745
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7745

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7746
<211>  1081
<212>  DNA
<213>  Homo sapiens

<400>  7746
gagaggggct gctggtctga ggctaagaag ggcagagcct tcgacccgga gagaggccgc     60

ggcccctgcc cagtgggcag cgtggaagtt tccatacaag gagacaccaa tgggaatccc    120

aatggggaag tcgatgctgg tgcttctcac cttcttggcc ttcgcctcgt gctgcattgc    180

tgcttaccgc cccagtgaga ccctgtgcgg cggggagctg gtggacaccc tccagttcgt    240

ctgtggggac cgcggcttct acttcagcag gcccgcaagc cgtgtgagcc gtcgcagccg    300

tggcatcgtt gaggagtgct gtttccgcag ctgtgacctg gccctcctgg agacgtactg    360

tgctaccccc gccaagtccg agagggacgt gtcgacccct ccgaccgtgc ttccggacaa    420

cttccccaga taccccgtgg gcaagttctt ccaatatgac acctggaagc agtccaccca    480

gcgcctgcgc aggggcctgc ctgccctcct gcgtgcccgc cggggtcacg tgctcgccaa    540

ggagctcgag gcgttcaggg aggccaaacg tcaccgtccc ctgattgctc tacccaccca    600

agaccccgcc cacgggggcg cccccccaga gatggccagc aatcggaagt gagcaaaact    660

gccgcaagtc tgcagcccgg cgccaccatc ctgcagcctc ctcctgacca cggacgtttc    720

catcaggttc catcccgaaa atctctcggt tccacgtccc cctggggctt ctcctgaccc    780

agtccccgtg ccccgcctcc ccgaaacagg ctactctcct cggccccctc catcgggctg    840

aggaagcaca gcagcatctt caaacatgta caaaatcgat tggctttaaa cacccttcac    900

ataccctccc cccaaattat ccccaattat ccccacacat aaaaaatcaa aacattaaac    960

taaccccctt cccccccccc cacaacaacc ctcttaaaac taattggctt tttagaaaca   1020

ccccacaaaa gctcagaaat tggctttaaa aaaaacaacc accaaaaaaa atcaattggc   1080

t                                                                   1081


<210>  7747
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7747

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7748
<211>  648
<212>  DNA
<213>  Homo sapiens

<400>  7748
ccccagtcac cgcctccccc ggcccctcga cgtggcgccc ttccctccgc ttctctgtgc     60

tccccgcgcc cctcttggcg tctggccccg gcccccgctc tttctcccgc aaccttccct    120

tcgctccctc ccgtcccccc cagctcctag cctccgactc cctccccccc tcacgcccgc    180

cctctcgcct tcgccgaacc aaagtggatt aattacacgc tttctgtttc tctccgtgct    240

gttctctccc gctgtgcgcc tgcccgcctc tcgctgtcct ctctccccct cgccctctct    300

tcggcccccc cctttcacgt tcactctgtc tctcccacta tctctgcccc cctctatcct    360

tgatacaaca gctgacctca tttcccgata ccttttcccc cccgaaaagt acaacatctg    420

gcccgcccca gcccgaagac agcccgtcct ccctggacaa tcagacgaat tcctcccccc    480

aaattatccc caattatccc cacacataaa aaatcaaaac attaaactaa cccccttccc    540

ccccccccac aacaaccctc ttaaaactaa ttggcttttt agaaacaccc cacaaaagct    600

cagaaattgg ctttaaaaaa aacaaccacc aaaaaaaatc aattggct                 648


<210>  7749
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  7749

Pro Ser His Arg Leu Pro Arg Pro Leu Asp Val Ala Pro Phe Pro Pro 
1               5                   10                  15


Leu Leu Cys Ala Pro Arg Ala Pro Leu Gly Val Trp Pro Arg Pro Pro 
            20                  25                  30


Leu Phe Leu Pro Gln Pro Ser Leu Arg Ser Leu Pro Ser Pro Pro Ala 
        35                  40                  45


Pro Ser Leu Arg Leu Pro Pro Pro Leu Thr Pro Ala Leu Ser Pro Ser 
    50                  55                  60


Pro Asn Gln Ser Gly Leu Ile Thr Arg Phe Leu Phe Leu Ser Val Leu 
65                  70                  75                  80


Phe Ser Pro Ala Val Arg Leu Pro Ala Ser Arg Cys Pro Leu Ser Pro 
                85                  90                  95


Ser Pro Ser Leu Arg Pro Pro Pro Phe Thr Phe Thr Leu Ser Leu Pro 
            100                 105                 110


Leu Ser Leu Pro Pro Ser Ile Leu Asp Thr Thr Ala Asp Leu Ile Ser 
        115                 120                 125


Arg Tyr Leu Phe Pro Pro Glu Lys Tyr Asn Ile Trp Pro Ala Pro Ala 
    130                 135                 140


Arg Arg Gln Pro Val Leu Pro Gly Gln Ser Asp Glu Phe Leu Pro Pro 
145                 150                 155                 160


Asn Tyr Pro Gln Leu Ser Pro His Ile Lys Asn Gln Asn Ile Lys Leu 
                165                 170                 175


Thr Pro Phe Pro Pro Pro His Asn Asn Pro Leu Lys Thr Asn Trp Leu 
            180                 185                 190


Phe Arg Asn Thr Pro Gln Lys Leu Arg Asn Trp Leu 
        195                 200


<210>  7750
<211>  2015
<212>  DNA
<213>  Homo sapiens

<400>  7750
cctgtccccc tcccgaggcc cgggctcgcg acggcagagg gctccgtcgg cccaaaccga     60

gctgggcgcc cgcggtccgg gtgcagcctc cactccgccc cccagtcacc gcctcccccg    120

gcccctcgac gtggcgccct tccctccgct tctctgtgct ccccgcgccc ctcttggcgt    180

ctggccccgg cccccgctct ttctcccgca accttccctt cgctccctcc cgtccccccc    240

agctcctagc ctccgactcc ctccccccct cacgcccgcc ctctcgcctt cgccgaacca    300

aagtggatta attacacgct ttctgtttct ctccgtgctg ttctctcccg ctgtgcgcct    360

gcccgcctct cgctgtcctc tctccccctc gccctctctt cggccccccc ctttcacgtt    420

cactctgtct ctcccactat ctctgccccc ctctatcctt gatacaacag ctgacctcat    480

ttcccgatac cttttccccc ccgaaaagta caacatctgg cccgccccag cccgaagaca    540

gcccgtcctc cctggacaat cagacgaatt ctcccccccc ccccaaaaaa aagccatccc    600

cccgctctgc cccgtcgcac attcggcccc cgcgactcgg ccagagcggc gctggcagag    660

gagtgtccgg caggagggcc aacgcccgct gttcggtttg cgacacgcag cagggaggtg    720

ggcggcagcg tcgccggctt ccagacacca atgggaatcc caatggggaa gtcgatgctg    780

gtgcttctca ccttcttggc cttcgcctcg tgctgcattg ctgcttaccg ccccagtgag    840

accctgtgcg gcggggagct ggtggacacc ctccagttcg tctgtgggga ccgcggcttc    900

tacttcagca ggcccgcaag ccgtgtgagc cgtcgcagcc gtggcatcgt tgaggagtgc    960

tgtttccgca gctgtgacct ggccctcctg gagacgtact gtgctacccc cgccaagtcc   1020

gagagggacg tgtcgacccc tccgaccgtg cttccggtga gggtcctggg cccctttccc   1080

actctctaga gacagagaaa tagggcttcg ggcgcccagc gtttcctgtg gcctctggga   1140

cctcttggcc agggacaagg acccgtgact tccttgcttg ctgtgtggcc cgggagcagc   1200

tcagacgctg gctccttctg tccctctgcc cgtggacatt agctcaagtc actgatcagt   1260

cacaggggtg gcctgtcagg tcaggcgggc ggctcaggcg gaagagcgtg gagagcaggc   1320

acctgctgac cagccccttc ccctcccagg acaacttccc cagatacccc gtgggcaagt   1380

tcttccaata tgacacctgg aagcagtcca cccagcgcct gcgcaggggc ctgcctgccc   1440

tcctgcgtgc ccgccggggt cacgtgctcg ccaaggagct cgaggcgttc agggaggcca   1500

aacgtcaccg tcccctgatt gctctaccca cccaagaccc cgcccacggg ggcgcccccc   1560

cagagatggc cagcaatcgg aagtgagcaa aactgccgca agtctgcagc ccggcgccac   1620

catcctgcag cctcctcctg accacggacg tttccatcag gttccatccc gaaaatctct   1680

cggttccacg tccccctggg gcttctcctg acccagtccc cgtgccccgc ctccccgaaa   1740

caggctactc tcctcggccc cctccatcgg gctgaggaag cacagcagca tcttcaaaca   1800

tgtacaaaat cgattggctt taaacaccct tcacataccc tccccccaaa ttatccccaa   1860

ttatccccac acataaaaaa tcaaaacatt aaactaaccc ccttcccccc cccccacaac   1920

aaccctctta aaactaattg gctttttaga aacaccccac aaaagctcag aaattggctt   1980

taaaaaaaac aaccaccaaa aaaaatcaat tggct                              2015


<210>  7751
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  7751

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Val Arg Val Leu Gly Pro Phe Pro Thr Leu 
            100                 105                 110


<210>  7752
<211>  2107
<212>  DNA
<213>  Homo sapiens

<400>  7752
gccggccccg gcccccccct tccggccgcc cccgcctcct ggcccacgcc tgcccgcgct     60

ctgcccacca gcgcctccat cgggcaaggc ggccccgcgt cgacgccgcc cgctgcctcg    120

ctgctgactc ccgtcccggg cgccgtccgc ggggtcgcgc tccgccgggc ctgcggattc    180

cccgccgcct cctcttcatc tacctcaact ccccccatcc ccgcttcgcc cgaggaggcg    240

gttccccccg caggcagtcc ggctcgcagg ccgccggcgt tgtcaccccc ccccgcgctc    300

cccctccagc cctccccccg gcgcgcagcc tcgggccgct cccctttccg cgctgcgtcc    360

cggagcggcc ccggtgccgc caccgcctgt ccccctcccg aggcccgggc tcgcgacggc    420

agagggctcc gtcggcccaa accgagctgg gcgcccgcgg tccgggtgca gcctccactc    480

cgccccccag tcaccgcctc ccccggcccc tcgacgtggc gcccttccct ccgcttctct    540

gtgctccccg cgcccctctt ggcgtctggc cccggccccc gctctttctc ccgcaacctt    600

cccttcgctc cctcccgtcc cccccagctc ctagcctccg actccctccc cccctcacgc    660

ccgccctctc gccttcgccg aaccaaagtg gattaattac acgctttctg tttctctccg    720

tgctgttctc tcccgctgtg cgcctgcccg cctctcgctg tcctctctcc ccctcgccct    780

ctcttcggcc cccccctttc acgttcactc tgtctctccc actatctctg cccccctcta    840

tccttgatac aacagctgac ctcatttccc gatacctttt cccccccgaa aagtacaaca    900

tctggcccgc cccagcccga agacagcccg tcctccctgg acaatcagac gaattctccc    960

ccccccccca aaaaaaagcc atccccccgc tctgccccgt cgcacattcg gcccccgcga   1020

ctcggccaga gcggcgctgg cagaggagtg tccggcagga gggccaacgc ccgctgttcg   1080

gtttgcgaca cgcagcaggg aggtgggcgg cagcgtcgcc ggcttccaga caccaatggg   1140

aatcccaatg gggaagtcga tgctggtgct tctcaccttc ttggccttcg cctcgtgctg   1200

cattgctgct taccgcccca gtgagaccct gtgcggcggg gagctggtgg acaccctcca   1260

gttcgtctgt ggggaccgcg gcttctactt cagcaggccc gcaagccgtg tgagccgtcg   1320

cagccgtggc atcgttgagg agtgctgttt ccgcagctgt gacctggccc tcctggagac   1380

gtactgtgct acccccgcca agtccgagag ggacgtgtcg acccctccga ccgtgcttcc   1440

ggacaacttc cccagatacc ccgtgggcaa gttcttccaa tatgacacct ggaagcagtc   1500

cacccagcgc ctgcgcaggg gcctgcctgc cctcctgcgt gcccgccggg gtcacgtgct   1560

cgccaaggag ctcgaggcgt tcagggaggc caaacgtcac cgtcccctga ttgctctacc   1620

cacccaagac cccgcccacg ggggcgcccc cccagagatg gccagcaatc ggaagtgagc   1680

aaaactgccg caagtctgca gcccggcgcc accatcctgc agcctcctcc tgaccacgga   1740

cgtttccatc aggttccatc ccgaaaatct ctcggttcca cgtccccctg gggcttctcc   1800

tgacccagtc cccgtgcccc gcctccccga aacaggctac tctcctcggc cccctccatc   1860

gggctgagga agcacagcag catcttcaaa catgtacaaa atcgattggc tttaaacacc   1920

cttcacatac cctcccccca aattatcccc aattatcccc acacataaaa aatcaaaaca   1980

ttaaactaac ccccttcccc cccccccaca acaaccctct taaaactaat tggcttttta   2040

gaaacacccc acaaaagctc agaaattggc tttaaaaaaa acaaccacca aaaaaaatca   2100

attggct                                                             2107


<210>  7753
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7753

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7754
<211>  1525
<212>  DNA
<213>  Homo sapiens

<400>  7754
cactgcagct tccccaaccc cgcgcacagc gggcactggt ttcgggcctc tctgtctcct     60

acgaagtccc cagagcaact cggatttggg aaatttctct ctagcgttgc ccaaacacac    120

ttgggtcggc cgcgcgccct caggacgtgg acagggaggg cttccccgtg tccaggaaag    180

cgaccgggca ttgcccccag tctcccccaa atttgggcat tgtccccggg tcttccaacg    240

gactgggcgt tgctcccgga cactgaggac tggccccggg gtctcgctca ccttcagcag    300

cgtccaccgc ctgccacaga gcgttcgatc gctcgctgcc tgagctcctg gtgcgcccgc    360

ggacgcagcc tccagcttcg cggagatggt ttccccagac ccccaaatta tcgtggtggc    420

ccccgagacc gaactcgcgt ctatgcaagt ccaacgcact gaggacgggg taaccattat    480

ccagatattt tgggtgggcc gcaaaggcga gctacttaga cgcaccccgg tgagctcggc    540

catgcagaca ccaatgggaa tcccaatggg gaagtcgatg ctggtgcttc tcaccttctt    600

ggccttcgcc tcgtgctgca ttgctgctta ccgccccagt gagaccctgt gcggcgggga    660

gctggtggac accctccagt tcgtctgtgg ggaccgcggc ttctacttca gcaggcccgc    720

aagccgtgtg agccgtcgca gccgtggcat cgttgaggag tgctgtttcc gcagctgtga    780

cctggccctc ctggagacgt actgtgctac ccccgccaag tccgagaggg acgtgtcgac    840

ccctccgacc gtgcttccgg acaacttccc cagatacccc gtgggcaagt tcttccaata    900

tgacacctgg aagcagtcca cccagcgcct gcgcaggggc ctgcctgccc tcctgcgtgc    960

ccgccggggt cacgtgctcg ccaaggagct cgaggcgttc agggaggcca aacgtcaccg   1020

tcccctgatt gctctaccca cccaagaccc cgcccacggg ggcgcccccc cagagatggc   1080

cagcaatcgg aagtgagcaa aactgccgca agtctgcagc ccggcgccac catcctgcag   1140

cctcctcctg accacggacg tttccatcag gttccatccc gaaaatctct cggttccacg   1200

tccccctggg gcttctcctg acccagtccc cgtgccccgc ctccccgaaa caggctactc   1260

tcctcggccc cctccatcgg gctgaggaag cacagcagca tcttcaaaca tgtacaaaat   1320

cgattggctt taaacaccct tcacataccc tccccccaaa ttatccccaa ttatccccac   1380

acataaaaaa tcaaaacatt aaactaaccc ccttcccccc cccccacaac aaccctctta   1440

aaactaattg gctttttaga aacaccccac aaaagctcag aaattggctt taaaaaaaac   1500

aaccaccaaa aaaaatcaat tggct                                         1525


<210>  7755
<211>  236
<212>  PRT
<213>  Homo sapiens

<400>  7755

Met Val Ser Pro Asp Pro Gln Ile Ile Val Val Ala Pro Glu Thr Glu 
1               5                   10                  15


Leu Ala Ser Met Gln Val Gln Arg Thr Glu Asp Gly Val Thr Ile Ile 
            20                  25                  30


Gln Ile Phe Trp Val Gly Arg Lys Gly Glu Leu Leu Arg Arg Thr Pro 
        35                  40                  45


Val Ser Ser Ala Met Gln Thr Pro Met Gly Ile Pro Met Gly Lys Ser 
    50                  55                  60


Met Leu Val Leu Leu Thr Phe Leu Ala Phe Ala Ser Cys Cys Ile Ala 
65                  70                  75                  80


Ala Tyr Arg Pro Ser Glu Thr Leu Cys Gly Gly Glu Leu Val Asp Thr 
                85                  90                  95


Leu Gln Phe Val Cys Gly Asp Arg Gly Phe Tyr Phe Ser Arg Pro Ala 
            100                 105                 110


Ser Arg Val Ser Arg Arg Ser Arg Gly Ile Val Glu Glu Cys Cys Phe 
        115                 120                 125


Arg Ser Cys Asp Leu Ala Leu Leu Glu Thr Tyr Cys Ala Thr Pro Ala 
    130                 135                 140


Lys Ser Glu Arg Asp Val Ser Thr Pro Pro Thr Val Leu Pro Asp Asn 
145                 150                 155                 160


Phe Pro Arg Tyr Pro Val Gly Lys Phe Phe Gln Tyr Asp Thr Trp Lys 
                165                 170                 175


Gln Ser Thr Gln Arg Leu Arg Arg Gly Leu Pro Ala Leu Leu Arg Ala 
            180                 185                 190


Arg Arg Gly His Val Leu Ala Lys Glu Leu Glu Ala Phe Arg Glu Ala 
        195                 200                 205


Lys Arg His Arg Pro Leu Ile Ala Leu Pro Thr Gln Asp Pro Ala His 
    210                 215                 220


Gly Gly Ala Pro Pro Glu Met Ala Ser Asn Arg Lys 
225                 230                 235


<210>  7756
<211>  1966
<212>  DNA
<213>  Homo sapiens

<400>  7756
gccggccccg gcccccccct tccggccgcc cccgcctcct ggcccacgcc tgcccgcgct     60

ctgcccacca gcgcctccat cgggcaaggc ggccccgcgt cgacgccgcc cgctgcctcg    120

ctgctgactc ccgtcccggg cgccgtccgc ggggtcgcgc tccgccgggc ctgcggattc    180

cccgccgcct cctcttcatc tacctcaact ccccccatcc ccgcttcgcc cgaggaggcg    240

gttccccccg caggcagtcc ggctcgcagg ccgccggcgt tgtcaccccc ccccgcgctc    300

cccctccagc cctccccccg gcgcgcagcc tcgggccgct cccctttccg cgctgcgtcc    360

cggagcggcc ccggtgccgc caccgcctgt ccccctcccg aggcccgggc tcgcgacggc    420

agagggctcc gtcggcccaa accgagctgg gcgcccgcgg tccgggtgca gcctccactc    480

cgccccccag tcaccgcctc ccccggcccc tcgacgtggc gcccttccct ccgcttctct    540

gtgctccccg cgcccctctt ggcgtctggc cccggccccc gctctttctc ccgcaacctt    600

cccttcgctc cctcccgtcc cccccagctc ctagcctccg actccctccc cccctcacgc    660

ccgccctctc gccttcgccg aaccaaagtg gattaattac acgctttctg tttctctccg    720

tgctgttctc tcccgctgtg cgcctgcccg cctctcgctg tcctctctcc ccctcgccct    780

ctcttcggcc cccccctttc acgttcactc tgtctctccc actatctctg cccccctcta    840

tccttgatac aacagctgac ctcatttccc gatacctttt cccccccgaa aagtacaaca    900

tctggcccgc cccagcccga agacagcccg tcctccctgg acaatcagac gaattctccc    960

ccccccccca aaaaaaagcc atccccccgc tctgccccgt cgcacattcg gcccccgcga   1020

ctcggccaga gcggcgctgg cagaggagtg tccggcagga gggccaacgc ccgctgttcg   1080

gtttgcgaca cgcagcaggg aggtgggcgg cagcgtcgcc ggcttccaga caccaatggg   1140

aatcccaatg gggaagtcga tgctggtgct tctcaccttc ttggccttcg cctcgtgctg   1200

cattgctgct taccgcccca gtgagaccct gtgcggcggg gagctggtgg acaccctcca   1260

gttcgtctgt ggggaccgcg gcttctactt cagcaggccc gcaagccgtg tgagccgtcg   1320

cagccgtggc atcgttgagg agtgctgttt ccgcagctgt gacctggccc tcctggagac   1380

gtactgtgct acccccgcca agtccgagag ggacgtgtcg acccctccga ccgtgcttcc   1440

ggacaacttc cccagatacc ccgtgggcaa gttcttccaa tatgacacct ggaagcagtc   1500

cacccagcgc ctgcgcaggg gcctgcctgc cctcctgcgt gcccgccggg gtcacgtgct   1560

cgccaaggag ctcgaggcgt tcagggaggc caaacgtcac cgtcccctga ttgctctacc   1620

cacccaagac cccgcccacg ggggcgcccc cccagagatg gccagcaatc ggaagtgagc   1680

aaaactgccg caagtctgca gcccggcgcc accatcctgc agcctcctcc tgaccacgga   1740

cgtttccatc aggttccatc ccgaaaatct ctcggttcca cgtccccctg gggcttctcc   1800

tgacccagtc cccgtgcccc gcctccccga aacaggctac tctcctcggc cccctccatc   1860

gggctgagga agcacagcag catcttcaaa catgtacaaa atcgattggc tttaaacacc   1920

cttcacatac cctcccccca aattatcccc aattatcccc acacat                  1966


<210>  7757
<211>  180
<212>  PRT
<213>  Homo sapiens

<400>  7757

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175


Ser Asn Arg Lys 
            180


<210>  7758
<211>  1966
<212>  DNA
<213>  Homo sapiens

<400>  7758
tcccggcgga gtcctaggcc cgcgggctag aggcacttta ccgcccggcg ggagcgcctc     60

tcctccgcgt ccctcgcccc agccccctgc ccgccccact ttgggaccct ccagccgctt    120

tccccacaaa tgagatcttt gcaatgagca aacgaaagtg gcgcggattt cggggcgccc    180

agcaggagcg agcgcagccg ccagccgcaa gtccgcagcc gtgtcccgcg ccccacgccg    240

gcctccccgg cggcagccgg agacgagcgc cagcaccggc gggacagcag cagatgcggg    300

ccgagagccg gtcaggggcg cagaggcgga ggggatcggc gcggcgggga gctcaccgcg    360

aagctggagg ctgcgtccgc gggcgcacca ggagctcagg cagcgagcga tcgaacgctc    420

tgtggcaggc ggtggacgct gctgaagggc gccgcagacg aggcgctgac cttgcgctca    480

ctcccctcgc tggggaagga cacactcgct ggcgtcagcc cggccggcct gggaagtagg    540

actaaggacc cgaactgcaa ccctccacac cagacagcac agaccacccc aaggctgctc    600

aatctgccca aagccaaaag agctcccctg ccaggacctc ggtgccgtgg agactgcggg    660

gaacctgctc tgcccacacc tgctctggcc cctagacgga agcacctgga gccaaccacg    720

gaactccaga tcccagctgt gtgactgaat ccacgccagc ctctctgagc caaagctgct    780

tgcagaaggg ggagatccca gttcgaagac tcccgcgcag agcctgtggc cctctctgcc    840

aggcctcagg gtgcctgaga cactcacctc tctgcctcgc agttggggct gaggctgggg    900

ctggctgcca gcctcagttc tgggagcgct ggggtcgcct gggccacagg ccacagcagc    960

tcacctcagg actgggctct ctggcctgct ggggctcagg ctgtggggca ggctgggcag   1020

ggggctgagc tggcagcgat tcagagccct ggggctgggg gctggaatcc acctcctccc   1080

acacaagctc ggtggtgact cttcggcccc tggggaaaaa caaaaagata ttgctgagat   1140

gacctctttt aaaagcaaag cccccctccc catacacccc aagcctgagc cctgtcccat   1200

ccccctcccc gggttccttc aggtcacctt gtcaggatct gggcagcggc ttccccctct   1260

agcccctccc ctgcctagag ctccctcttt caaagtataa gggagggaag aagtggtgag   1320

aagtttgcct agaaagggct tcccggtgct gatggagagg ccgagaccct tctgttggac   1380

aggctgccct gttcctgggt gaggatgggc ttctgcctgg cactgggggt ggagggtgca   1440

cacgaatggc ccgccttgag gggtcatggc acggaatatg aaagcctcct ccacctccaa   1500

acacccccac cttggaagga gataaggagg gggccccagc aaaagccact ggacacacag   1560

ctctgcttga cgaggccagt gagggacggc gtggctgtgc ttcctgggga aatgaacccc   1620

ctccccacag acaccaccct gggtggatcg aggagtctgg gtccagggtg caacagagaa   1680

aaacttcatg catgaatgag cattcccagg gaaactgcct tggccccagg gcgcctctct   1740

gtgccaggga ggctgggaga gcagcaaggg ggaccaggtg cgccatcagg aggagagaag   1800

ctaaacctag gggggacatg gagggcggtt gttgcctctc ccggcatttc tcctcagtct   1860

cctgtccaat ttcttgctgg tggtcaggag gcatagggag gcaggaggga aggaagcttt   1920

acctgtaaaa tggtgtatat atgtataaat aaaatctctg cgccag                  1966


<210>  7759
<211>  131
<212>  PRT
<213>  Homo sapiens

<400>  7759

Met Ser Lys Arg Lys Trp Arg Gly Phe Arg Gly Ala Gln Gln Glu Arg 
1               5                   10                  15


Ala Gln Pro Pro Ala Ala Ser Pro Gln Pro Cys Pro Ala Pro His Ala 
            20                  25                  30


Gly Leu Pro Gly Gly Ser Arg Arg Arg Ala Pro Ala Pro Ala Gly Gln 
        35                  40                  45


Gln Gln Met Arg Ala Glu Ser Arg Ser Gly Ala Gln Arg Arg Arg Gly 
    50                  55                  60


Ser Ala Arg Arg Gly Ala His Arg Glu Ala Gly Gly Cys Val Arg Gly 
65                  70                  75                  80


Arg Thr Arg Ser Ser Gly Ser Glu Arg Ser Asn Ala Leu Trp Gln Ala 
                85                  90                  95


Val Asp Ala Ala Glu Gly Arg Arg Arg Arg Gly Ala Asp Leu Ala Leu 
            100                 105                 110


Thr Pro Leu Ala Gly Glu Gly His Thr Arg Trp Arg Gln Pro Gly Arg 
        115                 120                 125


Pro Gly Lys 
    130


<210>  7760
<211>  2061
<212>  DNA
<213>  Homo sapiens

<400>  7760
ggcccgcggg ctagaggcac tttaccgccc ggcgggagcg cctctcctcc gcgtccctcg     60

ccccagcccc ctgcccgccc cactttggga ccctccagcc gctttcccca caaatgagat    120

ctttgcaatg agcaaacgaa agtggcgcgg atttcggggc gcccagcagg agcgagcgca    180

gccgccagcc gcaagtccgc agccgtgtcc cgcgccccac gccggcctcc ccggcggcag    240

ccggagacga gcgccagcac cggcgggaca gcagcagatg cgggccgaga gccggtcagg    300

ggcgcagagg cggaggggat cggcgcggcg gggagctcac cgcgaagctg gaggctgcgt    360

ccgcgggcgc accaggagct caggcagcga gcgatcgaac gctctgtggc aggcggtgga    420

cgctgctgaa gctctggctc tgagctcacc gctccgccgt ccgtgggacc aagcccagca    480

ttttacaaac ccagctcctt tctccaaggg tcctcagagc gcccctccgt caccccctgc    540

agggcgccgc agacgaggcg ctgaccttgc gctcactccc ctcgctgggg aaggacacac    600

tcgctggcgt cagcccggcc ggcctgggaa gtaggactaa ggacccgaac tgcaaccctc    660

cacaccagac agcacagacc accccaaggc tgctcaatct gcccaaagcc aaaagagctc    720

ccctgccagg acctcggtgc cgtggagact gcggggaacc tgctctgccc acacctgctc    780

tggcccctag acggaagcac ctggagccaa ccacggaact ccagatccca gctgtgtgac    840

tgaatccacg ccagcctctc tgagccaaag ctgcttgcag aagggggaga tcccagttcg    900

aagactcccg cgcagagcct gtggccctct ctgccaggcc tcagggtgcc tgagacactc    960

acctctctgc ctcgcagttg gggctgaggc tggggctggc tgccagcctc agttctggga   1020

gcgctggggt cgcctgggcc acaggccaca gcagctcacc tcaggactgg gctctctggc   1080

ctgctggggc tcaggctgtg gggcaggctg ggcagggggc tgagctggca gcgattcaga   1140

gccctggggc tgggggctgg aatccacctc ctcccacaca agctcggtgg tgactcttcg   1200

gcccctgggg aaaaacaaaa agatattgct gagatgacct cttttaaaag caaagccccc   1260

ctccccatac accccaagcc tgagccctgt cccatccccc tccccgggtt ccttcaggtc   1320

accttgtcag gatctgggca gcggcttccc cctctagccc ctcccctgcc tagagctccc   1380

tctttcaaag tataagggag ggaagaagtg gtgagaagtt tgcctagaaa gggcttcccg   1440

gtgctgatgg agaggccgag acccttctgt tggacaggct gccctgttcc tgggtgagga   1500

tgggcttctg cctggcactg ggggtggagg gtgcacacga atggcccgcc ttgaggggtc   1560

atggcacgga atatgaaagc ctcctccacc tccaaacacc cccaccttgg aaggagataa   1620

ggagggggcc ccagcaaaag ccactggaca cacagctctg cttgacgagg ccagtgaggg   1680

acggcgtggc tgtgcttcct ggggaaatga accccctccc cacagacacc accctgggtg   1740

gatcgaggag tctgggtcca gggtgcaaca gagaaaaact tcatgcatga atgagcattc   1800

ccagggaaac tgccttggcc ccagggcgcc tctctgtgcc agggaggctg ggagagcagc   1860

aagggggacc aggtgcgcca tcaggaggag agaagctaaa cctagggggg acatggaggg   1920

cggttgttgc ctctcccggc atttctcctc agtctcctgt ccaatttctt gctggtggtc   1980

aggaggcata gggaggcagg agggaaggaa gctttacctg taaaatggtg tatatatgta   2040

taaataaaat ctctgcgcca g                                             2061


<210>  7761
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  7761

Met Ser Lys Arg Lys Trp Arg Gly Phe Arg Gly Ala Gln Gln Glu Arg 
1               5                   10                  15


Ala Gln Pro Pro Ala Ala Ser Pro Gln Pro Cys Pro Ala Pro His Ala 
            20                  25                  30


Gly Leu Pro Gly Gly Ser Arg Arg Arg Ala Pro Ala Pro Ala Gly Gln 
        35                  40                  45


Gln Gln Met Arg Ala Glu Ser Arg Ser Gly Ala Gln Arg Arg Arg Gly 
    50                  55                  60


Ser Ala Arg Arg Gly Ala His Arg Glu Ala Gly Gly Cys Val Arg Gly 
65                  70                  75                  80


Arg Thr Arg Ser Ser Gly Ser Glu Arg Ser Asn Ala Leu Trp Gln Ala 
                85                  90                  95


Val Asp Ala Ala Glu Ala Leu Ala Leu Ser Ser Pro Leu Arg Arg Pro 
            100                 105                 110


Trp Asp Gln Ala Gln His Phe Thr Asn Pro Ala Pro Phe Ser Lys Gly 
        115                 120                 125


Pro Gln Ser Ala Pro Pro Ser Pro Pro Ala Gly Arg Arg Arg Arg Gly 
    130                 135                 140


Ala Asp Leu Ala Leu Thr Pro Leu Ala Gly Glu Gly His Thr Arg Trp 
145                 150                 155                 160


Arg Gln Pro Gly Arg Pro Gly Lys 
                165


<210>  7762
<211>  2826
<212>  DNA
<213>  Homo sapiens

<400>  7762
cgcccggcgg gagcgcctct cctccgcgtc cctcgcccca gccccctgcc cgccccactt     60

tgggaccctc cagccgcttt ccccacaaat gagatctttg caatgagcaa acgaaagtgg    120

cgcggatttc ggggcgccca gcaggagcga gcgcagccgc cagccgcaag tccgcagccg    180

tgtcccgcgc cccacgccgg cctccccggc ggcagccgga gacgagcgcc agcaccggcg    240

ggacagcagc agatgcgggc cgagagccgg tcaggggcgc agaggcggag gggatcggcg    300

cggcggggag ctcaccgcga agctggaggc tgcgtccgcg ggcgcaccag gagctcaggc    360

agcgagcgat cgaacgctct gtggcaggcg gtggacgctg ctgaagctct ggctctgagc    420

tcaccgctcc gccgtccgtg ggaccaagcc cagcatttta caaacccagc tcctttctcc    480

aagggtcctc agagcgcccc tccgtcaccc cctgcagggc gccgcagacg aggcgctgac    540

cttgcgctca ctcccctcgc tggggaagga cacactcgct ggcgtcagcc cggccggcct    600

gggaagtagg actaaggacc cgaactgcaa ccctccacac cagacagcac agaccacccc    660

aaggctgctc aatctgccca aagccaaaag tacgtggggg atatgggtcc aggttggggt    720

gcttgggaga gggccctggg agaggggttc agacggtgca cactccaaag gactgaggcg    780

gcgccactgt gttaccattt tattgagtgt ctaaggtaaa gacacctttg aaagaacact    840

cccggcttct atctgggatg ggcaaatcag cctgaagagt cacctgctgg atccctccct    900

gcaggccctg tcgtggggca ggtacaggga ctccaatcca tgtgcctcca gctccaacgc    960

tccccaagtc ctggagcctc ccctgtcacc ccagtgcctg accagtgaat gggtgctgcc   1020

cccactacag agctccctct ggctgaggca gaggccactg gctgggcctt tctagccacc   1080

tttcacccct cttgcacacg ggaagccccg caggctcctg accacaatgg gatcctgacg   1140

ccggagcccc ttaggccctt tgctcagaag gcctctggtt attacctcaa ttctgaacag   1200

ccaggaggcc tgagactgtc acccactttg ataaatacag accgacagaa aggtcaggcc   1260

attggtgcaa gaccccatgg ccagcagcct ggggcgggga gaacccgggg gtctcacagc   1320

ccccagcaga gcccagcttt ccttgggttt ttaggttctt ccccaatgat attttccctt   1380

tttccctctc tacccacttt ctgcccccca tcttctcccc tttggctgcc cgctctctcc   1440

ctgcccctct ccccttcttt gccctctttc gtctcccagg agctcccctg ccaggacctc   1500

ggtgccgtgg agactgcggg gaacctgctc tgcccacacc tgctctggcc cctagacgga   1560

agcacctgga gccaaccacg gaactccaga tcccagctgt gtgactgaat ccacgccagc   1620

ctctctgagc caaagctgct tgcagaaggg ggagatccca gttcgaagac tcccgcgcag   1680

agcctgtggc cctctctgcc aggcctcagg gtgcctgaga cactcacctc tctgcctcgc   1740

agttggggct gaggctgggg ctggctgcca gcctcagttc tgggagcgct ggggtcgcct   1800

gggccacagg ccacagcagc tcacctcagg actgggctct ctggcctgct ggggctcagg   1860

ctgtggggca ggctgggcag ggggctgagc tggcagcgat tcagagccct ggggctgggg   1920

gctggaatcc acctcctccc acacaagctc ggtggtgact cttcggcccc tggggaaaaa   1980

caaaaagata ttgctgagat gacctctttt aaaagcaaag cccccctccc catacacccc   2040

aagcctgagc cctgtcccat ccccctcccc gggttccttc aggtcacctt gtcaggatct   2100

gggcagcggc ttccccctct agcccctccc ctgcctagag ctccctcttt caaagtataa   2160

gggagggaag aagtggtgag aagtttgcct agaaagggct tcccggtgct gatggagagg   2220

ccgagaccct tctgttggac aggctgccct gttcctgggt gaggatgggc ttctgcctgg   2280

cactgggggt ggagggtgca cacgaatggc ccgccttgag gggtcatggc acggaatatg   2340

aaagcctcct ccacctccaa acacccccac cttggaagga gataaggagg gggccccagc   2400

aaaagccact ggacacacag ctctgcttga cgaggccagt gagggacggc gtggctgtgc   2460

ttcctgggga aatgaacccc ctccccacag acaccaccct gggtggatcg aggagtctgg   2520

gtccagggtg caacagagaa aaacttcatg catgaatgag cattcccagg gaaactgcct   2580

tggccccagg gcgcctctct gtgccaggga ggctgggaga gcagcaaggg ggaccaggtg   2640

cgccatcagg aggagagaag ctaaacctag gggggacatg gagggcggtt gttgcctctc   2700

ccggcatttc tcctcagtct cctgtccaat ttcttgctgg tggtcaggag gcatagggag   2760

gcaggaggga aggaagcttt acctgtaaaa tggtgtatat atgtataaat aaaatctctg   2820

cgccag                                                              2826


<210>  7763
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  7763

Met Ser Lys Arg Lys Trp Arg Gly Phe Arg Gly Ala Gln Gln Glu Arg 
1               5                   10                  15


Ala Gln Pro Pro Ala Ala Ser Pro Gln Pro Cys Pro Ala Pro His Ala 
            20                  25                  30


Gly Leu Pro Gly Gly Ser Arg Arg Arg Ala Pro Ala Pro Ala Gly Gln 
        35                  40                  45


Gln Gln Met Arg Ala Glu Ser Arg Ser Gly Ala Gln Arg Arg Arg Gly 
    50                  55                  60


Ser Ala Arg Arg Gly Ala His Arg Glu Ala Gly Gly Cys Val Arg Gly 
65                  70                  75                  80


Arg Thr Arg Ser Ser Gly Ser Glu Arg Ser Asn Ala Leu Trp Gln Ala 
                85                  90                  95


Val Asp Ala Ala Glu Ala Leu Ala Leu Ser Ser Pro Leu Arg Arg Pro 
            100                 105                 110


Trp Asp Gln Ala Gln His Phe Thr Asn Pro Ala Pro Phe Ser Lys Gly 
        115                 120                 125


Pro Gln Ser Ala Pro Pro Ser Pro Pro Ala Gly Arg Arg Arg Arg Gly 
    130                 135                 140


Ala Asp Leu Ala Leu Thr Pro Leu Ala Gly Glu Gly His Thr Arg Trp 
145                 150                 155                 160


Arg Gln Pro Gly Arg Pro Gly Lys 
                165


<210>  7764
<211>  482
<212>  DNA
<213>  Homo sapiens

<400>  7764
gccgtccatg ggaacaccca gccggcccca ctcgcacggg tagagacagg ggcgccctgc     60

tggagctgag cctcagcttt gtccctctcc tcctccacgt caacctggcc agagggtctg    120

gacgccacag ccagggcacc ccctgctttg gtggtgactg ctaatattgg ccaggccggc    180

ggatcatcgt ccaggcagtt tcggcagaga gccttgggca ccagtgactc cccggtcctc    240

tttatccact gtccaggagc tgcggggact gcgcagggac tagagtacag gtaactgggc    300

tcccatccct tgagtgtgag agaaaagctg cactttaagt gttcaggcgt gggtgggccg    360

ggagcttggg gcagctgcca ggatcctggt ttctgaagga ggggaagaac ttctgctgct    420

ggagggtgca gggaagcctc ctgagagcag cctcaacttc agggatgggg tgtgcaggaa    480

ag                                                                   482


<210>  7765
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  7765

Ala Ser Ala Leu Ser Leu Ser Ser Ser Thr Ser Thr Trp Pro Glu Gly 
1               5                   10                  15


Leu Asp Ala Thr Ala Arg Ala Pro Pro Ala Leu Val Val Thr Ala Asn 
            20                  25                  30


Ile Gly Gln Ala Gly Gly Ser Ser Ser Arg Gln Phe Arg Gln Arg Ala 
        35                  40                  45


Leu Gly Thr Ser Asp Ser Pro Val Leu Phe Ile His Cys Pro Gly Ala 
    50                  55                  60


Ala Gly Thr Ala Gln Gly Leu Glu Tyr Arg 
65                  70


<210>  7766
<211>  505
<212>  DNA
<213>  Homo sapiens

<400>  7766
agcagccctc agccctccag gacaggctgc atcagaagag gccatcaagc aggtctgttc     60

caagggcctt tgcgtcagat cactgtcctt ctgccatggc cctgtggatg cgcctcctgc    120

ccctgctggc gctgctggcc ctctggggac ctgacccagc cgcagccttt gtgaaccaac    180

acctgtgcgg ctcacacctg gtggaagctc tctacctagt gtgcggggaa cgaggcttct    240

tctacacacc caagacccgc cgggaggcag aggacctgca ggtggggcag gtggagctgg    300

gcgggggccc tggtgcaggc agcctgcagc ccttggccct ggaggggtcc ctgcagaagc    360

gtggcattgt ggaacaatgc tgtaccagca tctgctccct ctaccagctg gagaactact    420

gcaactagac gcagcccgca ggcagcccca cacccgccgc ctcctgcacc gagagagatg    480

gaataaagcc cttgaaccag ccctg                                          505


<210>  7767
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  7767

Met Ala Leu Trp Met Arg Leu Leu Pro Leu Leu Ala Leu Leu Ala Leu 
1               5                   10                  15


Trp Gly Pro Asp Pro Ala Ala Ala Phe Val Asn Gln His Leu Cys Gly 
            20                  25                  30


Ser His Leu Val Glu Ala Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe 
        35                  40                  45


Phe Tyr Thr Pro Lys Thr Arg Arg Glu Ala Glu Asp Leu Gln Val Gly 
    50                  55                  60


Gln Val Glu Leu Gly Gly Gly Pro Gly Ala Gly Ser Leu Gln Pro Leu 
65                  70                  75                  80


Ala Leu Glu Gly Ser Leu Gln Lys Arg Gly Ile Val Glu Gln Cys Cys 
                85                  90                  95


Thr Ser Ile Cys Ser Leu Tyr Gln Leu Glu Asn Tyr Cys Asn 
            100                 105                 110


<210>  7768
<211>  358
<212>  DNA
<213>  Homo sapiens

<400>  7768
aggacaggct gcatcagaag aggccatcaa gcaggtctgt tccaagggcc tttgcgtcag     60

atcactgtcc ttctgccatg gccctgtgga tgcgcctcct gcccctgctg gcgctgctgg    120

ccctctgggg acctgaccca gccgcagcct ttgtgaacca acacctgtgc ggctcacacc    180

tggtggaagc tctctaccta gtgtgcgggg aacgaggctt cttctacaca cccaagaccc    240

gccgggaggc agaggacctg caggctggag aactactgca actagacgca gcccgcaggc    300

agccccacac ccgccgcctc ctgcaccgag agagatggaa taaagccctt gaaccagc      358


<210>  7769
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  7769

Met Ala Leu Trp Met Arg Leu Leu Pro Leu Leu Ala Leu Leu Ala Leu 
1               5                   10                  15


Trp Gly Pro Asp Pro Ala Ala Ala Phe Val Asn Gln His Leu Cys Gly 
            20                  25                  30


Ser His Leu Val Glu Ala Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe 
        35                  40                  45


Phe Tyr Thr Pro Lys Thr Arg Arg Glu Ala Glu Asp Leu Gln Ala Gly 
    50                  55                  60


Glu Leu Leu Gln Leu Asp Ala Ala Arg Arg Gln Pro His Thr Arg Arg 
65                  70                  75                  80


Leu Leu His Arg Glu Arg Trp Asn Lys Ala Leu Glu 
                85                  90


<210>  7770
<211>  644
<212>  DNA
<213>  Homo sapiens

<400>  7770
agccctccag gacaggctgc atcagaagag gccatcaagc aggtctgttc caagggcctt     60

tgcgtcaggt gggctcagga ttccagggtg gctggacccc aggccccagc tctgcagcag    120

ggaggacgtg gctgggctcg tgaagcatgt gggggtgagc ccaggggccc caaggcaggg    180

cacctggcct tcagcctgcc tcagccctgc ctgtctccca gatcactgtc cttctgccat    240

ggccctgtgg atgcgcctcc tgcccctgct ggcgctgctg gccctctggg gacctgaccc    300

agccgcagcc tttgtgaacc aacacctgtg cggctcacac ctggtggaag ctctctacct    360

agtgtgcggg gaacgaggct tcttctacac acccaagacc cgccgggagg cagaggacct    420

gcaggtgggg caggtggagc tgggcggggg ccctggtgca ggcagcctgc agcccttggc    480

cctggagggg tccctgcaga agcgtggcat tgtggaacaa tgctgtacca gcatctgctc    540

cctctaccag ctggagaact actgcaacta gacgcagccc gcaggcagcc ccacacccgc    600

cgcctcctgc accgagagag atggaataaa gcccttgaac cagc                     644


<210>  7771
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  7771

Met Ala Leu Trp Met Arg Leu Leu Pro Leu Leu Ala Leu Leu Ala Leu 
1               5                   10                  15


Trp Gly Pro Asp Pro Ala Ala Ala Phe Val Asn Gln His Leu Cys Gly 
            20                  25                  30


Ser His Leu Val Glu Ala Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe 
        35                  40                  45


Phe Tyr Thr Pro Lys Thr Arg Arg Glu Ala Glu Asp Leu Gln Val Gly 
    50                  55                  60


Gln Val Glu Leu Gly Gly Gly Pro Gly Ala Gly Ser Leu Gln Pro Leu 
65                  70                  75                  80


Ala Leu Glu Gly Ser Leu Gln Lys Arg Gly Ile Val Glu Gln Cys Cys 
                85                  90                  95


Thr Ser Ile Cys Ser Leu Tyr Gln Leu Glu Asn Tyr Cys Asn 
            100                 105                 110


<210>  7772
<211>  483
<212>  DNA
<213>  Homo sapiens

<400>  7772
catcaagcag gtctgttcca agggcctttg cgtcaggtgg gctcaggatt ccagggtggc     60

tggaccccag gccccagctc tgcagcaggg aggacgtggc tgggctcgtg aagcatgtgg    120

gggtgagccc aggggcccca aggcagggca cctggccttc agcctgcctc agccctgcct    180

gtctcccaga tcactgtcct tctgccatgg ccctgtggat gcgcctcctg cccctgctgg    240

cgctgctggc cctctgggga cctgacccag ccgcagcctt tgtgaaccaa cacctgtgcg    300

gctcacacct ggtggaagct ctctacctag tgtgcgggga acgaggcttc ttctacacac    360

ccaagacccg ccgggaggca gaggacctgc aggctggaga actactgcaa ctagacgcag    420

cccgcaggca gccccacacc cgccgcctcc tgcaccgaga gagatggaat aaagcccttg    480

aac                                                                  483


<210>  7773
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  7773

Met Ala Leu Trp Met Arg Leu Leu Pro Leu Leu Ala Leu Leu Ala Leu 
1               5                   10                  15


Trp Gly Pro Asp Pro Ala Ala Ala Phe Val Asn Gln His Leu Cys Gly 
            20                  25                  30


Ser His Leu Val Glu Ala Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe 
        35                  40                  45


Phe Tyr Thr Pro Lys Thr Arg Arg Glu Ala Glu Asp Leu Gln Ala Gly 
    50                  55                  60


Glu Leu Leu Gln Leu Asp Ala Ala Arg Arg Gln Pro His Thr Arg Arg 
65                  70                  75                  80


Leu Leu His Arg Glu Arg Trp Asn Lys Ala Leu 
                85                  90


<210>  7774
<211>  2154
<212>  DNA
<213>  Homo sapiens

<400>  7774
tgggctgcca gaaagcccct ccctgtgtgc tctcttgagg gctgtggggc caaggggacc     60

ctggctgtct cagccccccg cagagcacga gcccctggtc cccgcaagcc cgcgggctga    120

ggatgattca gacagggctg gggagtgaag gcaattagat tccacggacg agccctttct    180

cctgcgcctc cctccttcct cacccacccc cgcctccatc aggcacagca ggcaggggtg    240

ggggatgtaa ggaggggaag gtgggggacc cagagggggc tttgacgtca gctcagctta    300

taagaggctg ctgggccagg gctgtggaga cggagcccgg acctccacac tgagccatgc    360

ccacccccga cgccaccacg ccacaggcca agggcttccg cagggccgtg tctgagctgg    420

acgccaagca ggcagaggcc atcatgtccc cgcggttcat tgggcgcagg cagagcctca    480

tcgaggacgc ccgcaaggag cgggaggcgg cggtggcagc agcggccgct gcagtcccct    540

cggagcccgg ggaccccctg gaggctgtgg cctttgagga gaaggagggg aaggccgtgc    600

taaacctgct cttctccccg agggccacca agccctcggc gctgtcccga gctgtgaagg    660

tgtttgagac gtttgaagcc aaaatccacc atctagagac ccggcccgcc cagaggccgc    720

gagctggggg cccccacctg gagtacttcg tgcgcctcga ggtgcgccga ggggacctgg    780

ccgccctgct cagtggtgtg cgccaggtgt cagaggacgt gcgcagcccc gcggggccca    840

aggtcccctg gttcccaaga aaagtgtcag agctggacaa gtgtcatcac ctggtcacca    900

agttcgaccc tgacctggac ttggaccacc cgggcttctc ggaccaggtg taccgccagc    960

gcaggaagct gattgctgag atcgccttcc agtacaggca cggcgacccg attccccgtg   1020

tggagtacac cgccgaggag attgccacct ggaaggaggt ctacaccacg ctgaagggcc   1080

tctacgccac gcacgcctgc ggggagcacc tggaggcctt tgctttgctg gagcgcttca   1140

gcggctaccg ggaagacaat atcccccagc tggaggacgt ctcccgcttc ctgaaggagc   1200

gcacgggctt ccagctgcgg cctgtggccg gcctgctgtc cgcccgggac ttcctggcca   1260

gcctggcctt ccgcgtgttc cagtgcaccc agtatatccg ccacgcgtcc tcgcccatgc   1320

actcccctga gccggactgc tgccacgagc tgctggggca cgtgcccatg ctggccgacc   1380

gcaccttcgc gcagttctcg caggacattg gcctggcgtc cctgggggcc tcggatgagg   1440

aaattgagaa gctgtccacg ctgtactggt tcacggtgga gttcgggctg tgtaagcaga   1500

acggggaggt gaaggcctat ggtgccgggc tgctgtcctc ctacggggag ctcctgcact   1560

gcctgtctga ggagcctgag attcgggcct tcgaccctga ggctgcggcc gtgcagccct   1620

accaagacca gacgtaccag tcagtctact tcgtgtctga gagcttcagt gacgccaagg   1680

acaagctcag gagctatgcc tcacgcatcc agcgcccctt ctccgtgaag ttcgacccgt   1740

acacgctggc catcgacgtg ctggacagcc cccaggccgt gcggcgctcc ctggagggtg   1800

tccaggatga gctggacacc cttgcccatg cgctgagtgc cattggctag gtgcacggcg   1860

tccctgaggg cccttcccaa cctcccctgg tcctgcactg tcccggagct caggccctgg   1920

tgaggggctg ggtcccgggt gccccccatg ccctccctgc tgccaggctc ccactgcccc   1980

tgcacctgct tctcagcgca acagctgtgt gtgcccgtgg tgaggttgtg ctgcctgtgg   2040

tgaggtcctg tcctggctcc cagggtcctg ggggctgctg cactgccctc cgcccttccc   2100

tgacactgtc tgctgcccca atcaccgtca caataaaaga aactgtggtc tcta         2154


<210>  7775
<211>  497
<212>  PRT
<213>  Homo sapiens

<400>  7775

Met Pro Thr Pro Asp Ala Thr Thr Pro Gln Ala Lys Gly Phe Arg Arg 
1               5                   10                  15


Ala Val Ser Glu Leu Asp Ala Lys Gln Ala Glu Ala Ile Met Ser Pro 
            20                  25                  30


Arg Phe Ile Gly Arg Arg Gln Ser Leu Ile Glu Asp Ala Arg Lys Glu 
        35                  40                  45


Arg Glu Ala Ala Val Ala Ala Ala Ala Ala Ala Val Pro Ser Glu Pro 
    50                  55                  60


Gly Asp Pro Leu Glu Ala Val Ala Phe Glu Glu Lys Glu Gly Lys Ala 
65                  70                  75                  80


Val Leu Asn Leu Leu Phe Ser Pro Arg Ala Thr Lys Pro Ser Ala Leu 
                85                  90                  95


Ser Arg Ala Val Lys Val Phe Glu Thr Phe Glu Ala Lys Ile His His 
            100                 105                 110


Leu Glu Thr Arg Pro Ala Gln Arg Pro Arg Ala Gly Gly Pro His Leu 
        115                 120                 125


Glu Tyr Phe Val Arg Leu Glu Val Arg Arg Gly Asp Leu Ala Ala Leu 
    130                 135                 140


Leu Ser Gly Val Arg Gln Val Ser Glu Asp Val Arg Ser Pro Ala Gly 
145                 150                 155                 160


Pro Lys Val Pro Trp Phe Pro Arg Lys Val Ser Glu Leu Asp Lys Cys 
                165                 170                 175


His His Leu Val Thr Lys Phe Asp Pro Asp Leu Asp Leu Asp His Pro 
            180                 185                 190


Gly Phe Ser Asp Gln Val Tyr Arg Gln Arg Arg Lys Leu Ile Ala Glu 
        195                 200                 205


Ile Ala Phe Gln Tyr Arg His Gly Asp Pro Ile Pro Arg Val Glu Tyr 
    210                 215                 220


Thr Ala Glu Glu Ile Ala Thr Trp Lys Glu Val Tyr Thr Thr Leu Lys 
225                 230                 235                 240


Gly Leu Tyr Ala Thr His Ala Cys Gly Glu His Leu Glu Ala Phe Ala 
                245                 250                 255


Leu Leu Glu Arg Phe Ser Gly Tyr Arg Glu Asp Asn Ile Pro Gln Leu 
            260                 265                 270


Glu Asp Val Ser Arg Phe Leu Lys Glu Arg Thr Gly Phe Gln Leu Arg 
        275                 280                 285


Pro Val Ala Gly Leu Leu Ser Ala Arg Asp Phe Leu Ala Ser Leu Ala 
    290                 295                 300


Phe Arg Val Phe Gln Cys Thr Gln Tyr Ile Arg His Ala Ser Ser Pro 
305                 310                 315                 320


Met His Ser Pro Glu Pro Asp Cys Cys His Glu Leu Leu Gly His Val 
                325                 330                 335


Pro Met Leu Ala Asp Arg Thr Phe Ala Gln Phe Ser Gln Asp Ile Gly 
            340                 345                 350


Leu Ala Ser Leu Gly Ala Ser Asp Glu Glu Ile Glu Lys Leu Ser Thr 
        355                 360                 365


Leu Tyr Trp Phe Thr Val Glu Phe Gly Leu Cys Lys Gln Asn Gly Glu 
    370                 375                 380


Val Lys Ala Tyr Gly Ala Gly Leu Leu Ser Ser Tyr Gly Glu Leu Leu 
385                 390                 395                 400


His Cys Leu Ser Glu Glu Pro Glu Ile Arg Ala Phe Asp Pro Glu Ala 
                405                 410                 415


Ala Ala Val Gln Pro Tyr Gln Asp Gln Thr Tyr Gln Ser Val Tyr Phe 
            420                 425                 430


Val Ser Glu Ser Phe Ser Asp Ala Lys Asp Lys Leu Arg Ser Tyr Ala 
        435                 440                 445


Ser Arg Ile Gln Arg Pro Phe Ser Val Lys Phe Asp Pro Tyr Thr Leu 
    450                 455                 460


Ala Ile Asp Val Leu Asp Ser Pro Gln Ala Val Arg Arg Ser Leu Glu 
465                 470                 475                 480


Gly Val Gln Asp Glu Leu Asp Thr Leu Ala His Ala Leu Ser Ala Ile 
                485                 490                 495


Gly 



<210>  7776
<211>  2235
<212>  DNA
<213>  Homo sapiens

<400>  7776
tgggctgcca gaaagcccct ccctgtgtgc tctcttgagg gctgtggggc caaggggacc     60

ctggctgtct cagccccccg cagagcacga gcccctggtc cccgcaagcc cgcgggctga    120

ggatgattca gacagggctg gggagtgaag gcaattagat tccacggacg agccctttct    180

cctgcgcctc cctccttcct cacccacccc cgcctccatc aggcacagca ggcaggggtg    240

ggggatgtaa ggaggggaag gtgggggacc cagagggggc tttgacgtca gctcagctta    300

taagaggctg ctgggccagg gctgtggaga cggagcccgg acctccacac tgagccatgc    360

ccacccccga cgccaccacg ccacaggcca agggcttccg cagggccgtg tctgagctgg    420

acgccaagca ggcagaggcc atcatgggcg ccccggggcc cagcctcaca ggctctccgt    480

ggcctggaac tgcagcccca gctgcatcct acacccccac cccaaggtcc ccgcggttca    540

ttgggcgcag gcagagcctc atcgaggacg cccgcaagga gcgggaggcg gcggtggcag    600

cagcggccgc tgcagtcccc tcggagcccg gggaccccct ggaggctgtg gcctttgagg    660

agaaggaggg gaaggccgtg ctaaacctgc tcttctcccc gagggccacc aagccctcgg    720

cgctgtcccg agctgtgaag gtgtttgaga cgtttgaagc caaaatccac catctagaga    780

cccggcccgc ccagaggccg cgagctgggg gcccccacct ggagtacttc gtgcgcctcg    840

aggtgcgccg aggggacctg gccgccctgc tcagtggtgt gcgccaggtg tcagaggacg    900

tgcgcagccc cgcggggccc aaggtcccct ggttcccaag aaaagtgtca gagctggaca    960

agtgtcatca cctggtcacc aagttcgacc ctgacctgga cttggaccac ccgggcttct   1020

cggaccaggt gtaccgccag cgcaggaagc tgattgctga gatcgccttc cagtacaggc   1080

acggcgaccc gattccccgt gtggagtaca ccgccgagga gattgccacc tggaaggagg   1140

tctacaccac gctgaagggc ctctacgcca cgcacgcctg cggggagcac ctggaggcct   1200

ttgctttgct ggagcgcttc agcggctacc gggaagacaa tatcccccag ctggaggacg   1260

tctcccgctt cctgaaggag cgcacgggct tccagctgcg gcctgtggcc ggcctgctgt   1320

ccgcccggga cttcctggcc agcctggcct tccgcgtgtt ccagtgcacc cagtatatcc   1380

gccacgcgtc ctcgcccatg cactcccctg agccggactg ctgccacgag ctgctggggc   1440

acgtgcccat gctggccgac cgcaccttcg cgcagttctc gcaggacatt ggcctggcgt   1500

ccctgggggc ctcggatgag gaaattgaga agctgtccac gctgtactgg ttcacggtgg   1560

agttcgggct gtgtaagcag aacggggagg tgaaggccta tggtgccggg ctgctgtcct   1620

cctacgggga gctcctgcac tgcctgtctg aggagcctga gattcgggcc ttcgaccctg   1680

aggctgcggc cgtgcagccc taccaagacc agacgtacca gtcagtctac ttcgtgtctg   1740

agagcttcag tgacgccaag gacaagctca ggagctatgc ctcacgcatc cagcgcccct   1800

tctccgtgaa gttcgacccg tacacgctgg ccatcgacgt gctggacagc ccccaggccg   1860

tgcggcgctc cctggagggt gtccaggatg agctggacac ccttgcccat gcgctgagtg   1920

ccattggcta ggtgcacggc gtccctgagg gcccttccca acctcccctg gtcctgcact   1980

gtcccggagc tcaggccctg gtgaggggct gggtcccggg tgccccccat gccctccctg   2040

ctgccaggct cccactgccc ctgcacctgc ttctcagcgc aacagctgtg tgtgcccgtg   2100

gtgaggttgt gctgcctgtg gtgaggtcct gtcctggctc ccagggtcct gggggctgct   2160

gcactgccct ccgcccttcc ctgacactgt ctgctgcccc aatcaccgtc acaataaaag   2220

aaactgtggt ctcta                                                    2235


<210>  7777
<211>  524
<212>  PRT
<213>  Homo sapiens

<400>  7777

Met Pro Thr Pro Asp Ala Thr Thr Pro Gln Ala Lys Gly Phe Arg Arg 
1               5                   10                  15


Ala Val Ser Glu Leu Asp Ala Lys Gln Ala Glu Ala Ile Met Gly Ala 
            20                  25                  30


Pro Gly Pro Ser Leu Thr Gly Ser Pro Trp Pro Gly Thr Ala Ala Pro 
        35                  40                  45


Ala Ala Ser Tyr Thr Pro Thr Pro Arg Ser Pro Arg Phe Ile Gly Arg 
    50                  55                  60


Arg Gln Ser Leu Ile Glu Asp Ala Arg Lys Glu Arg Glu Ala Ala Val 
65                  70                  75                  80


Ala Ala Ala Ala Ala Ala Val Pro Ser Glu Pro Gly Asp Pro Leu Glu 
                85                  90                  95


Ala Val Ala Phe Glu Glu Lys Glu Gly Lys Ala Val Leu Asn Leu Leu 
            100                 105                 110


Phe Ser Pro Arg Ala Thr Lys Pro Ser Ala Leu Ser Arg Ala Val Lys 
        115                 120                 125


Val Phe Glu Thr Phe Glu Ala Lys Ile His His Leu Glu Thr Arg Pro 
    130                 135                 140


Ala Gln Arg Pro Arg Ala Gly Gly Pro His Leu Glu Tyr Phe Val Arg 
145                 150                 155                 160


Leu Glu Val Arg Arg Gly Asp Leu Ala Ala Leu Leu Ser Gly Val Arg 
                165                 170                 175


Gln Val Ser Glu Asp Val Arg Ser Pro Ala Gly Pro Lys Val Pro Trp 
            180                 185                 190


Phe Pro Arg Lys Val Ser Glu Leu Asp Lys Cys His His Leu Val Thr 
        195                 200                 205


Lys Phe Asp Pro Asp Leu Asp Leu Asp His Pro Gly Phe Ser Asp Gln 
    210                 215                 220


Val Tyr Arg Gln Arg Arg Lys Leu Ile Ala Glu Ile Ala Phe Gln Tyr 
225                 230                 235                 240


Arg His Gly Asp Pro Ile Pro Arg Val Glu Tyr Thr Ala Glu Glu Ile 
                245                 250                 255


Ala Thr Trp Lys Glu Val Tyr Thr Thr Leu Lys Gly Leu Tyr Ala Thr 
            260                 265                 270


His Ala Cys Gly Glu His Leu Glu Ala Phe Ala Leu Leu Glu Arg Phe 
        275                 280                 285


Ser Gly Tyr Arg Glu Asp Asn Ile Pro Gln Leu Glu Asp Val Ser Arg 
    290                 295                 300


Phe Leu Lys Glu Arg Thr Gly Phe Gln Leu Arg Pro Val Ala Gly Leu 
305                 310                 315                 320


Leu Ser Ala Arg Asp Phe Leu Ala Ser Leu Ala Phe Arg Val Phe Gln 
                325                 330                 335


Cys Thr Gln Tyr Ile Arg His Ala Ser Ser Pro Met His Ser Pro Glu 
            340                 345                 350


Pro Asp Cys Cys His Glu Leu Leu Gly His Val Pro Met Leu Ala Asp 
        355                 360                 365


Arg Thr Phe Ala Gln Phe Ser Gln Asp Ile Gly Leu Ala Ser Leu Gly 
    370                 375                 380


Ala Ser Asp Glu Glu Ile Glu Lys Leu Ser Thr Leu Tyr Trp Phe Thr 
385                 390                 395                 400


Val Glu Phe Gly Leu Cys Lys Gln Asn Gly Glu Val Lys Ala Tyr Gly 
                405                 410                 415


Ala Gly Leu Leu Ser Ser Tyr Gly Glu Leu Leu His Cys Leu Ser Glu 
            420                 425                 430


Glu Pro Glu Ile Arg Ala Phe Asp Pro Glu Ala Ala Ala Val Gln Pro 
        435                 440                 445


Tyr Gln Asp Gln Thr Tyr Gln Ser Val Tyr Phe Val Ser Glu Ser Phe 
    450                 455                 460


Ser Asp Ala Lys Asp Lys Leu Arg Ser Tyr Ala Ser Arg Ile Gln Arg 
465                 470                 475                 480


Pro Phe Ser Val Lys Phe Asp Pro Tyr Thr Leu Ala Ile Asp Val Leu 
                485                 490                 495


Asp Ser Pro Gln Ala Val Arg Arg Ser Leu Glu Gly Val Gln Asp Glu 
            500                 505                 510


Leu Asp Thr Leu Ala His Ala Leu Ser Ala Ile Gly 
        515                 520


<210>  7778
<211>  938
<212>  DNA
<213>  Homo sapiens

<400>  7778
tgccattcca gtaggatgtg acttgcttct cctggccatg gttgtgaggc ctccccagct     60

atgtggaact atgttgagaa ggaacaacat gatctaagtc tttagaaacc aagagccacg    120

actagctgag gacacaagaa ttttcacaaa acaaagtaga gtgattccat agatcactat    180

tatagctgca ttaccagtcc taggacagaa tatggatgct gaaaaatgat tctttcaaag    240

tgctgagttg ttgcctcacg cccagttgtc tggcatctct tcactgaaac tattacagtt    300

agatctcatc tctatgggtg gaagattttt ctctgttgcc caggctagag tgcagtggtg    360

cgatctcagc tcactgcgac ctcctccacc agggttcagg ggattctcat gcctcagcct    420

ccagagtagc tgggattatg atcatgtgcc accacacctg gcttattttt gtaattatag    480

tagtgatggt gttttgccat gttggcccag ctggtctcga actcctgaac tcaagtgatc    540

caccctcctc ggcctcccaa agtgctggga ttataggcat gagccaccgt gcccagctgt    600

tttttactca ctttttgtct cacagtcatt aggcattcat ttctgccatt atgttgaaat    660

tgtcaatatt accaaagacc tagttgcccc aaacaatcaa cacctctatg tttatattaa    720

ttgataattc tatatttttc actattaacc taccatagta tccactccta taaacttccc    780

ttttcattgt ttttttgtaa atacagatca actttgctat cctcttacat ctgtgcctgc    840

ttctttgtct atctcctttg agatctttct ttttactgag agcaaaattt gtcctagttt    900

cccaatgttt ctctccaaac cttttttttt tttttttt                            938


<210>  7779
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  7779

Met Gly Gly Arg Phe Phe Ser Val Ala Gln Ala Arg Val Gln Trp Cys 
1               5                   10                  15


Asp Leu Ser Ser Leu Arg Pro Pro Pro Pro Gly Phe Arg Gly Phe Ser 
            20                  25                  30


Cys Leu Ser Leu Gln Ser Ser Trp Asp Tyr Asp His Val Pro Pro His 
        35                  40                  45


Leu Ala Tyr Phe Cys Asn Tyr Ser Ser Asp Gly Val Leu Pro Cys Trp 
    50                  55                  60


Pro Ser Trp Ser Arg Thr Pro Glu Leu Lys 
65                  70


<210>  7780
<211>  1159
<212>  DNA
<213>  Homo sapiens

<400>  7780
ctctttttgc ctgctgccat tccagtagga tgtgacttgc ttctcctggc catggttgtg     60

aggcctcccc agctatgtgg aactatgttg agaaggaaca acatgatcta agtctttaga    120

aaccaagagc cacgactagc tgaggacaca agaattttca caaaacaaag tagagtgatt    180

ccatagatca ctattatagc tgcattacca gtcctaggac agaatatgga tgctgaaaaa    240

tgattctttc aaagtgctga gttgttgcct cacgcccagt tgtctggcat ctcttcactg    300

aaactattac agttagatct catctctatg ggtggaaggt tgttgttctc aactcagcag    360

gaaatgtctt atgaagaaaa tggcccctgc tccttaggta gcaggccata ggcaaatact    420

gaccctcttg ccttctgaag ctaagctcca gcttcagtat gcacttgctt acctccttcc    480

cctgtccaca ctgcttttac ttgctccctg tctcctgaga gcattcatta ataaattgca    540

cacatttgaa tccctatctc aggtattgct catagagagt ccaacttaag aaaaactgca    600

atccttattt atattctgtt tcattaagag atgtaattgt gaaagaactg aacatataaa    660

aaaatcagct ttatcatgtt ttttatcctt gtcacgccat gtcacctgag caacacagtc    720

tgaatactaa attgtgagtg tgagtgcata tatgtgatgg taggtttttg tcctgttttc    780

aatcattcat aaaaccaaac atgtgtccct taattatgct ctactacatc cacaacttat    840

tttattcata aaaatattgt ggggtagata ttatcactgt tttcttgatg gggaaattta    900

atataaaaaa gttaaatatt ccctccaagg gcataacatt tttaattggt atagtcatga    960

ttcaaattta tatcttctaa ctataaggcc agtgtgaatg gtactccact acagtagact   1020

atccttagtg gcttctactt tttgccttgt attccgtcat gcttgtagta cctactttct   1080

ttttctgaaa atttctcctc cttctactcc aaaaatattg ttccctatga aaactgatat   1140

tttgcattgt atctccaaa                                                1159


<210>  7781
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  7781

Met Val Leu His Tyr Ser Arg Leu Ser Leu Val Ala Ser Thr Phe Cys 
1               5                   10                  15


Leu Val Phe Arg His Ala Cys Ser Thr Tyr Phe Leu Phe Leu Lys Ile 
            20                  25                  30


Ser Pro Pro Ser Thr Pro Lys Ile Leu Phe Pro Met Lys Thr Asp Ile 
        35                  40                  45


Leu His Cys Ile Ser 
    50


<210>  7782
<211>  1026
<212>  DNA
<213>  Homo sapiens

<400>  7782
ctctttttgc ctgctgccat tccagtagga tgtgacttgc ttctcctggc catggttgtg     60

aggcctcccc agctatgtgg aactatgttg agaaggaaca acatgatcta agtctttaga    120

aaccaagagc cacgactagc tgaggacaca agaattttca caaaacaaag tagagtgatt    180

ccatagatca ctattatagc tgcattacca gtcctaggac agaatatgga tgctgaaaaa    240

tgattctttc aaagtgctga gttgttgcct cacgcccagt tgtctggcat ctcttcactg    300

aaactattac agttagatct catctctatg ggtggaagga aaaaattctg agaatgatat    360

agtcgaagtg ataccttgaa ggtagaactg tgcactgtgg taataacaga aacagaaaga    420

catttcttct atataaaccc aggatgtcgt ccagcggcag ctcccatccc ttcctattga    480

ctggttttcc aggcttggag gaagctcatc actggatttc cgtatttttc ttgttcatgt    540

atatatccat cctttttggc aatggcaccc tccttcttct cattaaggaa gatcacaatc    600

ttcatgagcc catgtacttc tttctggcca tgctggctgc cacagacctg gggctggccc    660

tgaccacaat gcccacggtg ctgggagtcc tctggctgga tcacagggag attggaagtg    720

cggcctgctt ttcccaggcc tactttatac actcactttc ctttctcgag tctggcattc    780

tgcttgccat ggcctatgac cgttttattg ccatctgcaa ccctcttaga tatacctctg    840

tacttactaa tactcgagta gtgaagattg ggctgggagt tctgatgagg ggatttgtat    900

ccgttgttcc cccaatcagg cccctctatt tttttctgta ttgtcactcc catgttcttt    960

cacatgcatt ctgccttcac caggatgtca ttaaactcgc ctgtgctgat accaccttca   1020

accgac                                                              1026


<210>  7783
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  7783

Met Ser Ser Ser Gly Ser Ser His Pro Phe Leu Leu Thr Gly Phe Pro 
1               5                   10                  15


Gly Leu Glu Glu Ala His His Trp Ile Ser Val Phe Phe Leu Phe Met 
            20                  25                  30


Tyr Ile Ser Ile Leu Phe Gly Asn Gly Thr Leu Leu Leu Leu Ile Lys 
        35                  40                  45


Glu Asp His Asn Leu His Glu Pro Met Tyr Phe Phe Leu Ala Met Leu 
    50                  55                  60


Ala Ala Thr Asp Leu Gly Leu Ala Leu Thr Thr Met Pro Thr Val Leu 
65                  70                  75                  80


Gly Val Leu Trp Leu Asp His Arg Glu Ile Gly Ser Ala Ala Cys Phe 
                85                  90                  95


Ser Gln Ala Tyr Phe Ile His Ser Leu Ser Phe Leu Glu Ser Gly Ile 
            100                 105                 110


Leu Leu Ala Met Ala Tyr Asp Arg Phe Ile Ala Ile Cys Asn Pro Leu 
        115                 120                 125


Arg Tyr Thr Ser Val Leu Thr Asn Thr Arg Val Val Lys Ile Gly Leu 
    130                 135                 140


Gly Val Leu Met Arg Gly Phe Val Ser Val Val Pro Pro Ile Arg Pro 
145                 150                 155                 160


Leu Tyr Phe Phe Leu Tyr Cys His Ser His Val Leu Ser His Ala Phe 
                165                 170                 175


Cys Leu His Gln Asp Val Ile Lys Leu Ala Cys Ala Asp Thr Thr Phe 
            180                 185                 190


Asn 



<210>  7784
<211>  2413
<212>  DNA
<213>  Homo sapiens

<400>  7784
cagaaggcct caggggtggc tgtgtagcaa gatgagggag gtttggagcc ctgcataaag     60

agaaggacgg gaccacagct gactggatga tcttggtctc caatccccat gcccctagct    120

gtgtccccac agatctgggc ctcctgctgc caccatggcc aaaggtggag aagccctgcc    180

acagggcagc ccagcaccag tccaggatcc ccacctcatc aaggtgacag tgaagacgcc    240

caaagacaag gaggatttct cagttacaga cacatgcact atccagcagc tgaaggaaga    300

gatatctcag cgctttaagg cccaccccga tcagcttgtt ctaatctttg ctggcaaaat    360

cctcaaggat cctgactcac tggcacagtg tggagtgcga gatggcctca ctgtccacct    420

ggtcatcaag aggcagcacc gtgccatggg caatgagtgc ccagctgcct ctgtccctac    480

ccagggccca agtcctggat cactccctca gccaagctcc atttacccag cagatgggcc    540

ccctgccttt agcttaggtc tcctcacagg cctcagtagg ctgggcttgg cctatcgtgg    600

cttccctgac cagccaagct ccctgatgcg gcagcatgtg tctgtgcctg agtttgtgac    660

tcagctcatt gatgacccct tcatcccggg tctgctgtcc aacacaggcc tagtacgcca    720

gctggttctt gacaaccccc atatgcagca gctgatccag cacaaccctg agattgggca    780

tattcttaac aacccggaaa ttatgcggca gacactggag tttttacgta accctgccat    840

gatgcaggag atgatacgta gccaggaccg ggtgctcagt aacttggaga gcattcctgg    900

tggctacaat gtgctttgca ctatgtacac agatattatg gacccaatgc ttaacgcagt    960

ccaggagcag tttggcggca atccctttgc cactgccact actgataatg ccaccaccac   1020

caccagccaa ccttcaagga tggagaattg tgaccctctc cccaacccct ggacttccac   1080

acatggaggc tcaggtagca ggcaaggaag gcaggatggg gatcaggatg cacctgacat   1140

tagaaatagg tttccaaact ttctgggtat tataaggctc tatgactatc tccagcaatt   1200

acacgagaac ccccagtccc taggaactta tctacagggg actgcatctg ccctcagcca   1260

aagccaggaa ccaccaccat cagtaaacag agttccccca tcgtcaccct catctcagga   1320

gcctgggtca ggccagcctc tccccgagga gtcagtagca atcaagggaa ggtcctcctg   1380

cccagctttc ctgagatacc ccacagagaa cagtactgga caaggtggag accaagatgg   1440

tgcagggaaa agctctactg gacatagcac aaacttgcct gatcttgtct cggggctggg   1500

agattctgcc aacagggttc catttgctcc cttatctttt tcccccacgg cagccattcc   1560

tggaatccct gagcctccct ggctgccatc cccggcttat ccaagatctc tgaggccaga   1620

tggcatgaat ccagctccac agttacagga tgagatacaa ccacagctgc cactgctgat   1680

gcaccttcag gcagccatgg caaacccccg tgccctgcaa gccctgcggc agattgagca   1740

gggtctacag gtcctagcta ctgaagcacc tcgcctccta ctctggttca tgccttgcct   1800

agcagggacg ggtagtgtgg caggaggtat agagtctaga gaagatcccc ttatgtctga   1860

ggatcctctc ccaaatccac ctcctgaggt gttcccagca ctggactctg cagagctggg   1920

cttcctttcc cctccctttc tccatatgct gcaagattta gttagtacaa atccccagca   1980

gctgcagcct gaggctcact ttcaggtgca gctggagcaa ctgcggtcca tgggctttct   2040

gaatcgtgaa gccaatcttc aggccctcat tgctacgggg ggcgacgtgg atgctgctgt   2100

ggagaagctg agacagtcgt aggagcctta ttcattcaaa ccatacgttt tcctctgtgc   2160

ctttttccca tatcctagtt ccctagctct cccatttttg aatacagctg cattataaac   2220

caaatttact atgaagtcct ttgctgtgga ggcaatgttg ttccagagtc aacgaggaag   2280

actaatggcc aaaacatagt ggaggtgctg tgtgtgagtc aaccacttgt accactatac   2340

cactgggggg ccccagtcta agctctgctt atgcctatct tgagatgcaa ttacacccaa   2400

tttccaatgt gaa                                                      2413


<210>  7785
<211>  655
<212>  PRT
<213>  Homo sapiens

<400>  7785

Met Ala Lys Gly Gly Glu Ala Leu Pro Gln Gly Ser Pro Ala Pro Val 
1               5                   10                  15


Gln Asp Pro His Leu Ile Lys Val Thr Val Lys Thr Pro Lys Asp Lys 
            20                  25                  30


Glu Asp Phe Ser Val Thr Asp Thr Cys Thr Ile Gln Gln Leu Lys Glu 
        35                  40                  45


Glu Ile Ser Gln Arg Phe Lys Ala His Pro Asp Gln Leu Val Leu Ile 
    50                  55                  60


Phe Ala Gly Lys Ile Leu Lys Asp Pro Asp Ser Leu Ala Gln Cys Gly 
65                  70                  75                  80


Val Arg Asp Gly Leu Thr Val His Leu Val Ile Lys Arg Gln His Arg 
                85                  90                  95


Ala Met Gly Asn Glu Cys Pro Ala Ala Ser Val Pro Thr Gln Gly Pro 
            100                 105                 110


Ser Pro Gly Ser Leu Pro Gln Pro Ser Ser Ile Tyr Pro Ala Asp Gly 
        115                 120                 125


Pro Pro Ala Phe Ser Leu Gly Leu Leu Thr Gly Leu Ser Arg Leu Gly 
    130                 135                 140


Leu Ala Tyr Arg Gly Phe Pro Asp Gln Pro Ser Ser Leu Met Arg Gln 
145                 150                 155                 160


His Val Ser Val Pro Glu Phe Val Thr Gln Leu Ile Asp Asp Pro Phe 
                165                 170                 175


Ile Pro Gly Leu Leu Ser Asn Thr Gly Leu Val Arg Gln Leu Val Leu 
            180                 185                 190


Asp Asn Pro His Met Gln Gln Leu Ile Gln His Asn Pro Glu Ile Gly 
        195                 200                 205


His Ile Leu Asn Asn Pro Glu Ile Met Arg Gln Thr Leu Glu Phe Leu 
    210                 215                 220


Arg Asn Pro Ala Met Met Gln Glu Met Ile Arg Ser Gln Asp Arg Val 
225                 230                 235                 240


Leu Ser Asn Leu Glu Ser Ile Pro Gly Gly Tyr Asn Val Leu Cys Thr 
                245                 250                 255


Met Tyr Thr Asp Ile Met Asp Pro Met Leu Asn Ala Val Gln Glu Gln 
            260                 265                 270


Phe Gly Gly Asn Pro Phe Ala Thr Ala Thr Thr Asp Asn Ala Thr Thr 
        275                 280                 285


Thr Thr Ser Gln Pro Ser Arg Met Glu Asn Cys Asp Pro Leu Pro Asn 
    290                 295                 300


Pro Trp Thr Ser Thr His Gly Gly Ser Gly Ser Arg Gln Gly Arg Gln 
305                 310                 315                 320


Asp Gly Asp Gln Asp Ala Pro Asp Ile Arg Asn Arg Phe Pro Asn Phe 
                325                 330                 335


Leu Gly Ile Ile Arg Leu Tyr Asp Tyr Leu Gln Gln Leu His Glu Asn 
            340                 345                 350


Pro Gln Ser Leu Gly Thr Tyr Leu Gln Gly Thr Ala Ser Ala Leu Ser 
        355                 360                 365


Gln Ser Gln Glu Pro Pro Pro Ser Val Asn Arg Val Pro Pro Ser Ser 
    370                 375                 380


Pro Ser Ser Gln Glu Pro Gly Ser Gly Gln Pro Leu Pro Glu Glu Ser 
385                 390                 395                 400


Val Ala Ile Lys Gly Arg Ser Ser Cys Pro Ala Phe Leu Arg Tyr Pro 
                405                 410                 415


Thr Glu Asn Ser Thr Gly Gln Gly Gly Asp Gln Asp Gly Ala Gly Lys 
            420                 425                 430


Ser Ser Thr Gly His Ser Thr Asn Leu Pro Asp Leu Val Ser Gly Leu 
        435                 440                 445


Gly Asp Ser Ala Asn Arg Val Pro Phe Ala Pro Leu Ser Phe Ser Pro 
    450                 455                 460


Thr Ala Ala Ile Pro Gly Ile Pro Glu Pro Pro Trp Leu Pro Ser Pro 
465                 470                 475                 480


Ala Tyr Pro Arg Ser Leu Arg Pro Asp Gly Met Asn Pro Ala Pro Gln 
                485                 490                 495


Leu Gln Asp Glu Ile Gln Pro Gln Leu Pro Leu Leu Met His Leu Gln 
            500                 505                 510


Ala Ala Met Ala Asn Pro Arg Ala Leu Gln Ala Leu Arg Gln Ile Glu 
        515                 520                 525


Gln Gly Leu Gln Val Leu Ala Thr Glu Ala Pro Arg Leu Leu Leu Trp 
    530                 535                 540


Phe Met Pro Cys Leu Ala Gly Thr Gly Ser Val Ala Gly Gly Ile Glu 
545                 550                 555                 560


Ser Arg Glu Asp Pro Leu Met Ser Glu Asp Pro Leu Pro Asn Pro Pro 
                565                 570                 575


Pro Glu Val Phe Pro Ala Leu Asp Ser Ala Glu Leu Gly Phe Leu Ser 
            580                 585                 590


Pro Pro Phe Leu His Met Leu Gln Asp Leu Val Ser Thr Asn Pro Gln 
        595                 600                 605


Gln Leu Gln Pro Glu Ala His Phe Gln Val Gln Leu Glu Gln Leu Arg 
    610                 615                 620


Ser Met Gly Phe Leu Asn Arg Glu Ala Asn Leu Gln Ala Leu Ile Ala 
625                 630                 635                 640


Thr Gly Gly Asp Val Asp Ala Ala Val Glu Lys Leu Arg Gln Ser 
                645                 650                 655


<210>  7786
<211>  2407
<212>  DNA
<213>  Homo sapiens

<400>  7786
agggacctga tagtgcgggt tctggcccag aaggcctcag gggtggctgt gtagcaagat     60

gagggaggtt tggagccctg cataaagaga aggacgggac cacagctgac tgctgtgtcc    120

ccacagatct gggcctcctg ctgccaccat ggccaaaggt ggagaagccc tgccacaggg    180

cagcccagca ccagtccagg atccccacct catcaaggtg acagtgaaga cgcccaaaga    240

caaggaggat ttctcagtta cagacacatg cactatccag cagctgaagg aagagatatc    300

tcagcgcttt aaggcccacc ccgatcagct tgttctaatc tttgctggca aaatcctcaa    360

ggatcctgac tcactggcac agtgtggagt gcgagatggc ctcactgtcc acctggtcat    420

caagaggcag caccgtgcca tgggcaatga gtgcccagct gcctctgtcc ctacccaggg    480

cccaagtcct ggatcactcc ctcagccaag ctccatttac ccagcagatg ggccccctgc    540

ctttagctta ggtctcctca caggcctcag taggctgggc ttggcctatc gtggcttccc    600

tgaccagcca agctccctga tgcggcagca tgtgtctgtg cctgagtttg tgactcagct    660

cattgatgac cccttcatcc cgggtctgct gtccaacaca ggcctagtac gccagctggt    720

tcttgacaac ccccatatgc agcagctgat ccagcacaac cctgagattg ggcatattct    780

taacaacccg gaaattatgc ggcagacact ggagttttta cgtaaccctg ccatgatgca    840

ggagatgata cgtagccagg accgggtgct cagtaacttg gagagcattc ctggtggcta    900

caatgtgctt tgcactatgt acacagatat tatggaccca atgcttaacg cagtccagga    960

gcagtttggc ggcaatccct ttgccactgc cactactgat aatgccacca ccaccaccag   1020

ccaaccttca aggatggaga attgtgaccc tctccccaac ccctggactt ccacacatgg   1080

aggctcaggt agcaggcaag gaaggcagga tggggatcag gatgcacctg acattagaaa   1140

taggtttcca aactttctgg gtattataag gctctatgac tatctccagc aattacacga   1200

gaacccccag tccctaggaa cttatctaca ggggactgca tctgccctca gccaaagcca   1260

ggaaccacca ccatcagtaa acagagttcc cccatcgtca ccctcatctc aggagcctgg   1320

gtcaggccag cctctccccg aggagtcagt agcaatcaag ggaaggtcct cctgcccagc   1380

tttcctgaga taccccacag agaacagtac tggacaaggt ggagaccaag atggtgcagg   1440

gaaaagctct actggacata gcacaaactt gcctgatctt gtctcggggc tgggagattc   1500

tgccaacagg gttccatttg ctcccttatc tttttccccc acggcagcca ttcctggaat   1560

ccctgagcct ccctggctgc catccccggc ttatccaaga tctctgaggc cagatggcat   1620

gaatccagct ccacagttac aggatgagat acaaccacag ctgccactgc tgatgcacct   1680

tcaggcagcc atggcaaacc cccgtgccct gcaagccctg cggcagattg agcagggtct   1740

acaggtccta gctactgaag cacctcgcct cctactctgg ttcatgcctt gcctagcagg   1800

gacgggtagt gtggcaggag gtatagagtc tagagaagat ccccttatgt ctgaggatcc   1860

tctcccaaat ccacctcctg aggtgttccc agcactggac tctgcagagc tgggcttcct   1920

ttcccctccc tttctccata tgctgcaaga tttagttagt acaaatcccc agcagctgca   1980

gcctgaggct cactttcagg tgcagctgga gcaactgcgg tccatgggct ttctgaatcg   2040

tgaagccaat cttcaggccc tcattgctac ggggggcgac gtggatgctg ctgtggagaa   2100

gctgagacag tcgtaggagc cttattcatt caaaccatac gttttcctct gtgccttttt   2160

cccatatcct agttccctag ctctcccatt tttgaataca gctgcattat aaaccaaatt   2220

tactatgaag tcctttgctg tggaggcaat gttgttccag agtcaacgag gaagactaat   2280

ggccaaaaca tagtggaggt gctgtgtgtg agtcaaccac ttgtaccact ataccactgg   2340

ggggccccag tctaagctct gcttatgcct atcttgagat gcaattacac ccaatttcca   2400

atgtgaa                                                             2407


<210>  7787
<211>  655
<212>  PRT
<213>  Homo sapiens

<400>  7787

Met Ala Lys Gly Gly Glu Ala Leu Pro Gln Gly Ser Pro Ala Pro Val 
1               5                   10                  15


Gln Asp Pro His Leu Ile Lys Val Thr Val Lys Thr Pro Lys Asp Lys 
            20                  25                  30


Glu Asp Phe Ser Val Thr Asp Thr Cys Thr Ile Gln Gln Leu Lys Glu 
        35                  40                  45


Glu Ile Ser Gln Arg Phe Lys Ala His Pro Asp Gln Leu Val Leu Ile 
    50                  55                  60


Phe Ala Gly Lys Ile Leu Lys Asp Pro Asp Ser Leu Ala Gln Cys Gly 
65                  70                  75                  80


Val Arg Asp Gly Leu Thr Val His Leu Val Ile Lys Arg Gln His Arg 
                85                  90                  95


Ala Met Gly Asn Glu Cys Pro Ala Ala Ser Val Pro Thr Gln Gly Pro 
            100                 105                 110


Ser Pro Gly Ser Leu Pro Gln Pro Ser Ser Ile Tyr Pro Ala Asp Gly 
        115                 120                 125


Pro Pro Ala Phe Ser Leu Gly Leu Leu Thr Gly Leu Ser Arg Leu Gly 
    130                 135                 140


Leu Ala Tyr Arg Gly Phe Pro Asp Gln Pro Ser Ser Leu Met Arg Gln 
145                 150                 155                 160


His Val Ser Val Pro Glu Phe Val Thr Gln Leu Ile Asp Asp Pro Phe 
                165                 170                 175


Ile Pro Gly Leu Leu Ser Asn Thr Gly Leu Val Arg Gln Leu Val Leu 
            180                 185                 190


Asp Asn Pro His Met Gln Gln Leu Ile Gln His Asn Pro Glu Ile Gly 
        195                 200                 205


His Ile Leu Asn Asn Pro Glu Ile Met Arg Gln Thr Leu Glu Phe Leu 
    210                 215                 220


Arg Asn Pro Ala Met Met Gln Glu Met Ile Arg Ser Gln Asp Arg Val 
225                 230                 235                 240


Leu Ser Asn Leu Glu Ser Ile Pro Gly Gly Tyr Asn Val Leu Cys Thr 
                245                 250                 255


Met Tyr Thr Asp Ile Met Asp Pro Met Leu Asn Ala Val Gln Glu Gln 
            260                 265                 270


Phe Gly Gly Asn Pro Phe Ala Thr Ala Thr Thr Asp Asn Ala Thr Thr 
        275                 280                 285


Thr Thr Ser Gln Pro Ser Arg Met Glu Asn Cys Asp Pro Leu Pro Asn 
    290                 295                 300


Pro Trp Thr Ser Thr His Gly Gly Ser Gly Ser Arg Gln Gly Arg Gln 
305                 310                 315                 320


Asp Gly Asp Gln Asp Ala Pro Asp Ile Arg Asn Arg Phe Pro Asn Phe 
                325                 330                 335


Leu Gly Ile Ile Arg Leu Tyr Asp Tyr Leu Gln Gln Leu His Glu Asn 
            340                 345                 350


Pro Gln Ser Leu Gly Thr Tyr Leu Gln Gly Thr Ala Ser Ala Leu Ser 
        355                 360                 365


Gln Ser Gln Glu Pro Pro Pro Ser Val Asn Arg Val Pro Pro Ser Ser 
    370                 375                 380


Pro Ser Ser Gln Glu Pro Gly Ser Gly Gln Pro Leu Pro Glu Glu Ser 
385                 390                 395                 400


Val Ala Ile Lys Gly Arg Ser Ser Cys Pro Ala Phe Leu Arg Tyr Pro 
                405                 410                 415


Thr Glu Asn Ser Thr Gly Gln Gly Gly Asp Gln Asp Gly Ala Gly Lys 
            420                 425                 430


Ser Ser Thr Gly His Ser Thr Asn Leu Pro Asp Leu Val Ser Gly Leu 
        435                 440                 445


Gly Asp Ser Ala Asn Arg Val Pro Phe Ala Pro Leu Ser Phe Ser Pro 
    450                 455                 460


Thr Ala Ala Ile Pro Gly Ile Pro Glu Pro Pro Trp Leu Pro Ser Pro 
465                 470                 475                 480


Ala Tyr Pro Arg Ser Leu Arg Pro Asp Gly Met Asn Pro Ala Pro Gln 
                485                 490                 495


Leu Gln Asp Glu Ile Gln Pro Gln Leu Pro Leu Leu Met His Leu Gln 
            500                 505                 510


Ala Ala Met Ala Asn Pro Arg Ala Leu Gln Ala Leu Arg Gln Ile Glu 
        515                 520                 525


Gln Gly Leu Gln Val Leu Ala Thr Glu Ala Pro Arg Leu Leu Leu Trp 
    530                 535                 540


Phe Met Pro Cys Leu Ala Gly Thr Gly Ser Val Ala Gly Gly Ile Glu 
545                 550                 555                 560


Ser Arg Glu Asp Pro Leu Met Ser Glu Asp Pro Leu Pro Asn Pro Pro 
                565                 570                 575


Pro Glu Val Phe Pro Ala Leu Asp Ser Ala Glu Leu Gly Phe Leu Ser 
            580                 585                 590


Pro Pro Phe Leu His Met Leu Gln Asp Leu Val Ser Thr Asn Pro Gln 
        595                 600                 605


Gln Leu Gln Pro Glu Ala His Phe Gln Val Gln Leu Glu Gln Leu Arg 
    610                 615                 620


Ser Met Gly Phe Leu Asn Arg Glu Ala Asn Leu Gln Ala Leu Ile Ala 
625                 630                 635                 640


Thr Gly Gly Asp Val Asp Ala Ala Val Glu Lys Leu Arg Gln Ser 
                645                 650                 655


<210>  7788
<211>  2312
<212>  DNA
<213>  Homo sapiens

<400>  7788
cactttgtcc accatgggtg aattatgaat cagtagctat gccaggcctc agctgggcca     60

catctggaga actggggtga gggcacaaca tcacaaaata tctggcccca gtctggtcac    120

tcatcccttt tagggcaaca aggaaactat cctgtggcct gagagcacaa tacctgagac    180

aaaggccagc agaaacattt gtctgccctc accctttctg ccccagcttc cacctgctcc    240

ccatctgccc acccactaaa gcccatgtgg catgccatct ctcgaacatc caggatgtcc    300

cagagtggat gtccatcagg tctgctggca gacaaaaata tctcttcaag tgccactcga    360

gtgatagtga agactgcagg caaccagaaa gactttatgg tagctgatga catctcggta    420

aggcagttca aggagatgct attggctcac ttccaatgcc agatggacca actagtgctg    480

gtcttcatgg gttgccttct caaagaccat gacacactga gccagagggg catcatggat    540

ggccacacca tctacttggt catcaagtcc aagcagggct ccagatctct agcccattcc    600

ttccgggacc tgccaacgaa tgatccctgc caccgggaca gaaacaccaa aggaaacagc    660

agcagagtgc accaaccaac tggtatgaat caagctccag tggaactggc ccactttgtg    720

gggtctgatg cacccaaagt gcatacccaa aacttggaag tgagccaccc agagtgcaaa    780

gcacagatgc tggagaatcc tagcatccag cggcttctgt ccaacatgga gttcatgtgg    840

cagttcattt cagaacatct agacacgcaa caattgatgc agcagaaccc agaagtttcc    900

cgccttcttc ttgataattc tgagatccta ttgcagactc tggagctggc caggaacctt    960

gctatgatcc aagagataat gcagatccaa caaccttcac aaaaccttga gtatccactg   1020

aacccacagc catatctggg cttagagaca atgccaggtg ggaataatgc cctgggtcag   1080

aactatgctg atatcaatga tcaaatgctg aacagcatgc aagatccttt tggaggaaac   1140

cctttcacag ctctcctggc aggacaagtg ctagaacaag tccagtcttc acccccacct   1200

ccaccaccat cacaggaaca acaagaccag ctcacacagc atcctgcaac ccgagtcatc   1260

tataatagct ctggtggttt ctcttcaaac acctcagcca atgacaccct taacaaggtc   1320

aaccacactt ccaaagccaa cactgctatg atttccacca agggccagag ccatatctgt   1380

gccactcggc agccagcttg gataccagcc ttacctagca tagagcttac ccagcagctt   1440

caagaagaat acaaggatgc cactgtttct ctaagtagct ccagacagac attaaagggt   1500

gatctccagc tgtcagatga gcagagcagc tcccagatca caggaggcat gatgcagttg   1560

cttatgaaca acccctacct ggcagctcag attatgttgt tcacaagtat gccccagctg   1620

agtgaacagt ggaggcagca gctgcccaca ttcctgcagc agacacagat ttctgatctg   1680

cttagtgctt aggcaaccct aaagcattcc aagcaatatt gcagattgag caggccctcc   1740

agctgctggc cacagaggct cctgttcttc tgccttgggt tgcaccctac ctatggggcc   1800

tgggttggct tcctgccccc agctgcagct atcctgacac agtgccctgt tcctggaatg   1860

tttcagatac agctgagccc aagggacctg agtgctgcca caagcctgga acagtcctgc   1920

agaggctaca atccccggat ggggaccctt cccaccctct gcaagctcct gagatttgtt   1980

ttagcaaaca gatggattct ctccaggcca tgggatttgg gaaccaccat gccaatctac   2040

aggcactcat tgctactgaa ggggacacca atgctgctat ccgcaagctc aagagatccc   2100

agagattcta accaccatgc ctacttgttt gcttgctacc tgcctgctga cccacctgac   2160

catctcattt gccttttgca cctttcctga tgcttccagc caggagaagt cctggaataa   2220

gagttatcaa ccaatgtgtc ttgtactgaa taatagatca ttggtcgtgg ctgaaacatc   2280

tgtcaataaa atggctacac tcacttgctg cg                                 2312


<210>  7789
<211>  475
<212>  PRT
<213>  Homo sapiens

<400>  7789

Met Trp His Ala Ile Ser Arg Thr Ser Arg Met Ser Gln Ser Gly Cys 
1               5                   10                  15


Pro Ser Gly Leu Leu Ala Asp Lys Asn Ile Ser Ser Ser Ala Thr Arg 
            20                  25                  30


Val Ile Val Lys Thr Ala Gly Asn Gln Lys Asp Phe Met Val Ala Asp 
        35                  40                  45


Asp Ile Ser Val Arg Gln Phe Lys Glu Met Leu Leu Ala His Phe Gln 
    50                  55                  60


Cys Gln Met Asp Gln Leu Val Leu Val Phe Met Gly Cys Leu Leu Lys 
65                  70                  75                  80


Asp His Asp Thr Leu Ser Gln Arg Gly Ile Met Asp Gly His Thr Ile 
                85                  90                  95


Tyr Leu Val Ile Lys Ser Lys Gln Gly Ser Arg Ser Leu Ala His Ser 
            100                 105                 110


Phe Arg Asp Leu Pro Thr Asn Asp Pro Cys His Arg Asp Arg Asn Thr 
        115                 120                 125


Lys Gly Asn Ser Ser Arg Val His Gln Pro Thr Gly Met Asn Gln Ala 
    130                 135                 140


Pro Val Glu Leu Ala His Phe Val Gly Ser Asp Ala Pro Lys Val His 
145                 150                 155                 160


Thr Gln Asn Leu Glu Val Ser His Pro Glu Cys Lys Ala Gln Met Leu 
                165                 170                 175


Glu Asn Pro Ser Ile Gln Arg Leu Leu Ser Asn Met Glu Phe Met Trp 
            180                 185                 190


Gln Phe Ile Ser Glu His Leu Asp Thr Gln Gln Leu Met Gln Gln Asn 
        195                 200                 205


Pro Glu Val Ser Arg Leu Leu Leu Asp Asn Ser Glu Ile Leu Leu Gln 
    210                 215                 220


Thr Leu Glu Leu Ala Arg Asn Leu Ala Met Ile Gln Glu Ile Met Gln 
225                 230                 235                 240


Ile Gln Gln Pro Ser Gln Asn Leu Glu Tyr Pro Leu Asn Pro Gln Pro 
                245                 250                 255


Tyr Leu Gly Leu Glu Thr Met Pro Gly Gly Asn Asn Ala Leu Gly Gln 
            260                 265                 270


Asn Tyr Ala Asp Ile Asn Asp Gln Met Leu Asn Ser Met Gln Asp Pro 
        275                 280                 285


Phe Gly Gly Asn Pro Phe Thr Ala Leu Leu Ala Gly Gln Val Leu Glu 
    290                 295                 300


Gln Val Gln Ser Ser Pro Pro Pro Pro Pro Pro Ser Gln Glu Gln Gln 
305                 310                 315                 320


Asp Gln Leu Thr Gln His Pro Ala Thr Arg Val Ile Tyr Asn Ser Ser 
                325                 330                 335


Gly Gly Phe Ser Ser Asn Thr Ser Ala Asn Asp Thr Leu Asn Lys Val 
            340                 345                 350


Asn His Thr Ser Lys Ala Asn Thr Ala Met Ile Ser Thr Lys Gly Gln 
        355                 360                 365


Ser His Ile Cys Ala Thr Arg Gln Pro Ala Trp Ile Pro Ala Leu Pro 
    370                 375                 380


Ser Ile Glu Leu Thr Gln Gln Leu Gln Glu Glu Tyr Lys Asp Ala Thr 
385                 390                 395                 400


Val Ser Leu Ser Ser Ser Arg Gln Thr Leu Lys Gly Asp Leu Gln Leu 
                405                 410                 415


Ser Asp Glu Gln Ser Ser Ser Gln Ile Thr Gly Gly Met Met Gln Leu 
            420                 425                 430


Leu Met Asn Asn Pro Tyr Leu Ala Ala Gln Ile Met Leu Phe Thr Ser 
        435                 440                 445


Met Pro Gln Leu Ser Glu Gln Trp Arg Gln Gln Leu Pro Thr Phe Leu 
    450                 455                 460


Gln Gln Thr Gln Ile Ser Asp Leu Leu Ser Ala 
465                 470                 475


<210>  7790
<211>  1824
<212>  DNA
<213>  Homo sapiens

<400>  7790
ttattgtaga gccctggacc cctaaatatg tcctccttcc ccagctggcc cagggtgact     60

gcgaggatag agttgacatc acaatatccc ttttctgagg attcatgccc ctggtgggtg    120

gggtaggagg aggggtagcc ctaggagaag tcatcaccac tttgtccacc atgggtgaat    180

tatgaatcag tagctatgcc aggcctcagc tgggccacat ctggagaact ggggtgaggg    240

cacaacatca caaaatatct ggccccagtc tggtcactca tcccttttag ggcaacaagg    300

aaactatcct gtggcctgag agcacaatac ctgagacaaa ggccagcaga aacatttgtc    360

tgccctcacc ctttctgccc cagcttccac ctgctcccca tctgcccacc cactaaagcc    420

catgtggcat gccatctctc gaacatccag gatgtcccag agtggatgtc catcaggtct    480

gctggcagac aaaaatatct cttcaagtgc cactcgagtg atagtgaaga ctgcaggcaa    540

ccagaaagac tttatggtag ctgatgacat ctcggtaagg cagttcaagg agatgctatt    600

ggctcacttc caatgccaga tggaccaact agtgctggtc ttcatgggtt gccttctcaa    660

agaccatgac acactgagcc agaggggcat catggatggc cacaccatct acttggtcat    720

caagtccaag cagggctcca gatctctagc ccattccttc cgggacctgc caacgaatga    780

tccctgccac cgggacagaa acaacctcag ccaatgacac ccttaacaag gtcaaccaca    840

cttccaaagc caacactgct atgatttcca ccaagggcca gagccatatc tgtgccactc    900

ggcagccagc ttggatacca gccttaccta gcatagagct tacccagcag cttcaagaag    960

aatacaagga tgccactgtt tctctaagta gctccagaca gacattaaag ggtgatctcc   1020

agctgtcaga tgagcagagc agctcccaga tcacaggagg catgatgcag ttgcttatga   1080

acaaccccta cctggcagct cagattatgt tgttcacaag tatgccccag ctgagtgaac   1140

agtggaggca gcagctgccc acattcctgc agcagacaca gatttctgat ctgcttagtg   1200

cttaggcaac cctaaagcat tccaagcaat attgcagatt gagcaggccc tccagctgct   1260

ggccacagag gctcctgttc ttctgccttg ggttgcaccc tacctatggg gcctgggttg   1320

gcttcctgcc cccagctgca gctatcctga cacagtgccc tgttcctgga atgtttcaga   1380

tacagctgag cccaagggac ctgagtgctg ccacaagcct ggaacagtcc tgcagaggct   1440

acaatccccg gatggggacc cttcccaccc tctgcaagct cctgagattt gttttagcaa   1500

acagatggat tctctccagg ccatgggatt tgggaaccac catgccaatc tacaggcact   1560

cattgctact gaaggggaca ccaatgctgc tatccgcaag ctcaagagat cccagagatt   1620

ctaaccacca tgcctacttg tttgcttgct acctgcctgc tgacccacct gaccatctca   1680

tttgcctttt gcacctttcc tgatgcttcc agccaggaga agtcctggaa taagagttat   1740

caaccaatgt gtcttgtact gaataataga tcattggtcg tggctgaaac atctgtcaat   1800

aaaatggcta cactcacttg ctgc                                          1824


<210>  7791
<211>  142
<212>  PRT
<213>  Homo sapiens

<400>  7791

Met Ile Pro Ala Thr Gly Thr Glu Thr Thr Ser Ala Asn Asp Thr Leu 
1               5                   10                  15


Asn Lys Val Asn His Thr Ser Lys Ala Asn Thr Ala Met Ile Ser Thr 
            20                  25                  30


Lys Gly Gln Ser His Ile Cys Ala Thr Arg Gln Pro Ala Trp Ile Pro 
        35                  40                  45


Ala Leu Pro Ser Ile Glu Leu Thr Gln Gln Leu Gln Glu Glu Tyr Lys 
    50                  55                  60


Asp Ala Thr Val Ser Leu Ser Ser Ser Arg Gln Thr Leu Lys Gly Asp 
65                  70                  75                  80


Leu Gln Leu Ser Asp Glu Gln Ser Ser Ser Gln Ile Thr Gly Gly Met 
                85                  90                  95


Met Gln Leu Leu Met Asn Asn Pro Tyr Leu Ala Ala Gln Ile Met Leu 
            100                 105                 110


Phe Thr Ser Met Pro Gln Leu Ser Glu Gln Trp Arg Gln Gln Leu Pro 
        115                 120                 125


Thr Phe Leu Gln Gln Thr Gln Ile Ser Asp Leu Leu Ser Ala 
    130                 135                 140


<210>  7792
<211>  963
<212>  DNA
<213>  Homo sapiens

<400>  7792
atgccatctg cctctgccat gatcattttc aacctgagca gttacaatcc aggacccttc     60

attctggtag ggatcccagg cctggagcaa ttccatgtgt ggattggaat tcccttctgt    120

atcatctaca ttgtagctgt tgtgggaaac tgcatccttc tctacctcat tgtggtggag    180

catagtcttc atgaacccat gttcttcttt ctctccatgc tggccatgac tgacctcatc    240

ttgtccacag ctggtgtgcc taaagcactc agtatctttt ggctaggggc tcgcgaaatc    300

acattcccag gatgccttac acaaatgttc ttccttcact ataactttgt cctggattca    360

gccattctga tggccatggc atttgatcac tatgtagcta tctgttctcc cttgagatat    420

accaccatct tgactcccaa gaccatcatc aagagtgcta tgggcatctc ctttcgaagc    480

ttctgcatca tcctgccaga tgtattcttg ctgacatgcc tgcctttctg caggacacgc    540

atcatacccc acacatactg tgagcatata ggtgttgccc agctcgcctg tgctgatatc    600

tccatcaact tctggtatgg cttttgtgtt cccatcatga cggtcatctc agatgtgatt    660

ctcattgctg tttcctacgc acacatcctc tgtgctgtct ttggccttcc ctcccaagat    720

gcctgccaga aagccctcgg cacttgtggt tctcatgtct gtgtcatcct catgttttat    780

acacctgcct ttttctccat cctcgcccat cgctttggac acaatgtctc tcgcaccttc    840

cacatcatgt ttgccaatct ctacattgtt atcccacctg cactcaaccc catggtttac    900

ggagtgaaga ccaagcagat cagagataag gttatacttt tgttttctaa gggtacagga    960

tga                                                                  963


<210>  7793
<211>  320
<212>  PRT
<213>  Homo sapiens

<400>  7793

Met Pro Ser Ala Ser Ala Met Ile Ile Phe Asn Leu Ser Ser Tyr Asn 
1               5                   10                  15


Pro Gly Pro Phe Ile Leu Val Gly Ile Pro Gly Leu Glu Gln Phe His 
            20                  25                  30


Val Trp Ile Gly Ile Pro Phe Cys Ile Ile Tyr Ile Val Ala Val Val 
        35                  40                  45


Gly Asn Cys Ile Leu Leu Tyr Leu Ile Val Val Glu His Ser Leu His 
    50                  55                  60


Glu Pro Met Phe Phe Phe Leu Ser Met Leu Ala Met Thr Asp Leu Ile 
65                  70                  75                  80


Leu Ser Thr Ala Gly Val Pro Lys Ala Leu Ser Ile Phe Trp Leu Gly 
                85                  90                  95


Ala Arg Glu Ile Thr Phe Pro Gly Cys Leu Thr Gln Met Phe Phe Leu 
            100                 105                 110


His Tyr Asn Phe Val Leu Asp Ser Ala Ile Leu Met Ala Met Ala Phe 
        115                 120                 125


Asp His Tyr Val Ala Ile Cys Ser Pro Leu Arg Tyr Thr Thr Ile Leu 
    130                 135                 140


Thr Pro Lys Thr Ile Ile Lys Ser Ala Met Gly Ile Ser Phe Arg Ser 
145                 150                 155                 160


Phe Cys Ile Ile Leu Pro Asp Val Phe Leu Leu Thr Cys Leu Pro Phe 
                165                 170                 175


Cys Arg Thr Arg Ile Ile Pro His Thr Tyr Cys Glu His Ile Gly Val 
            180                 185                 190


Ala Gln Leu Ala Cys Ala Asp Ile Ser Ile Asn Phe Trp Tyr Gly Phe 
        195                 200                 205


Cys Val Pro Ile Met Thr Val Ile Ser Asp Val Ile Leu Ile Ala Val 
    210                 215                 220


Ser Tyr Ala His Ile Leu Cys Ala Val Phe Gly Leu Pro Ser Gln Asp 
225                 230                 235                 240


Ala Cys Gln Lys Ala Leu Gly Thr Cys Gly Ser His Val Cys Val Ile 
                245                 250                 255


Leu Met Phe Tyr Thr Pro Ala Phe Phe Ser Ile Leu Ala His Arg Phe 
            260                 265                 270


Gly His Asn Val Ser Arg Thr Phe His Ile Met Phe Ala Asn Leu Tyr 
        275                 280                 285


Ile Val Ile Pro Pro Ala Leu Asn Pro Met Val Tyr Gly Val Lys Thr 
    290                 295                 300


Lys Gln Ile Arg Asp Lys Val Ile Leu Leu Phe Ser Lys Gly Thr Gly 
305                 310                 315                 320


<210>  7794
<211>  471
<212>  DNA
<213>  Homo sapiens

<400>  7794
aggaagagaa aaggggaagg agcgtctagg tgaaatgagc tgtgtagtcc tttagagcct     60

ctggacagaa ggtctgatga atacatgtaa agcttattga gcctcagaac tctaactaca    120

gggtttcaat agcacagaaa ctctgagaag aaaaagaatg tcaaagttcc tccctaagga    180

gactgattag atgcaagtgt gtccggaatt ggtgggttct tggtctgact tcaagaatga    240

agccgcggac cctcacggtg ctgctgtttt actaagaggt atatgaataa tggaaatgcc    300

tcctgtaatc ctagcacttt gggaggccga ggcgggcgga tcacctgagg ttgggagttc    360

gagaccagcc tgaccaacat ggggaaaccc cctctctact aaaaatacaa aattagctgg    420

gcgtggtggt ccatgcctgt aatcccagct acttgggagg ctgaggcagg a             471


<210>  7795
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  7795

Met Gln Val Cys Pro Glu Leu Val Gly Ser Trp Ser Asp Phe Lys Asn 
1               5                   10                  15


Glu Ala Ala Asp Pro His Gly Ala Ala Val Leu Leu Arg Gly Ile 
            20                  25                  30


<210>  7796
<211>  1008
<212>  DNA
<213>  Homo sapiens

<400>  7796
atggcacagg tgagggcgct gcataaaatc atggcccttt tttctgctaa cagcataggt     60

gctatgaaca actctgacac tcgcatagca ggctgcttcc tcactggcat ccctgggctg    120

gagcaactac atatctggct gtccatcccc ttctgcatca tgtacatcac tgccctggaa    180

ggcaatggca tcctaatttg tgtcatcctc tcccaggcaa tcctgcatga gcccatgtac    240

atattcttat ctatgctggc cagtgctgat gtcttgctct ctaccaccac catgcctaag    300

gccctggcca atttgtggct aggttatagc ctcatttcct ttgatggctg cctcactcag    360

atgttcttca ttcacttcct cttcattcac tctgctgtcc tgctggccat ggcctttgac    420

cgctatgtgg ccatctgctc ccccctgcga tatgtcacaa tcctcacaag caaggtcatt    480

gggaagatcg tcactgccgc cctgagccac agcttcatca ttatgtttcc atccatcttt    540

ctccttgagc acctgcacta ttgccagatc aatatcattg cacacacatt ttgtgagcac    600

atgggcattg cccatctgtc ctgttctgat atctccatca atgtctggta tgggttggca    660

gctgctcttc tctccacagg cctagacatc atgcttatta ctgtttccta catccacatc    720

ctccaagcag tcttccgcct cctttctcaa gatgcccgct ccaaggccct gagtacctgt    780

ggatcccata tctgtgtcat cctactcttc tatgtccctg cgcttttttc tgtctttgcc    840

tacaggtttg gtgggagaag cgtcccatgc tatgtccata ttctcctggc cagcctctac    900

gttgtcattc ctcctatgct caatcccgtt atttatggag tgaggactaa gccaatactg    960

gaaggggcta agcagatgtt ttcaaatctt gccaaaggat ctaaataa                1008


<210>  7797
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  7797

Met Ala Gln Val Arg Ala Leu His Lys Ile Met Ala Leu Phe Ser Ala 
1               5                   10                  15


Asn Ser Ile Gly Ala Met Asn Asn Ser Asp Thr Arg Ile Ala Gly Cys 
            20                  25                  30


Phe Leu Thr Gly Ile Pro Gly Leu Glu Gln Leu His Ile Trp Leu Ser 
        35                  40                  45


Ile Pro Phe Cys Ile Met Tyr Ile Thr Ala Leu Glu Gly Asn Gly Ile 
    50                  55                  60


Leu Ile Cys Val Ile Leu Ser Gln Ala Ile Leu His Glu Pro Met Tyr 
65                  70                  75                  80


Ile Phe Leu Ser Met Leu Ala Ser Ala Asp Val Leu Leu Ser Thr Thr 
                85                  90                  95


Thr Met Pro Lys Ala Leu Ala Asn Leu Trp Leu Gly Tyr Ser Leu Ile 
            100                 105                 110


Ser Phe Asp Gly Cys Leu Thr Gln Met Phe Phe Ile His Phe Leu Phe 
        115                 120                 125


Ile His Ser Ala Val Leu Leu Ala Met Ala Phe Asp Arg Tyr Val Ala 
    130                 135                 140


Ile Cys Ser Pro Leu Arg Tyr Val Thr Ile Leu Thr Ser Lys Val Ile 
145                 150                 155                 160


Gly Lys Ile Val Thr Ala Ala Leu Ser His Ser Phe Ile Ile Met Phe 
                165                 170                 175


Pro Ser Ile Phe Leu Leu Glu His Leu His Tyr Cys Gln Ile Asn Ile 
            180                 185                 190


Ile Ala His Thr Phe Cys Glu His Met Gly Ile Ala His Leu Ser Cys 
        195                 200                 205


Ser Asp Ile Ser Ile Asn Val Trp Tyr Gly Leu Ala Ala Ala Leu Leu 
    210                 215                 220


Ser Thr Gly Leu Asp Ile Met Leu Ile Thr Val Ser Tyr Ile His Ile 
225                 230                 235                 240


Leu Gln Ala Val Phe Arg Leu Leu Ser Gln Asp Ala Arg Ser Lys Ala 
                245                 250                 255


Leu Ser Thr Cys Gly Ser His Ile Cys Val Ile Leu Leu Phe Tyr Val 
            260                 265                 270


Pro Ala Leu Phe Ser Val Phe Ala Tyr Arg Phe Gly Gly Arg Ser Val 
        275                 280                 285


Pro Cys Tyr Val His Ile Leu Leu Ala Ser Leu Tyr Val Val Ile Pro 
    290                 295                 300


Pro Met Leu Asn Pro Val Ile Tyr Gly Val Arg Thr Lys Pro Ile Leu 
305                 310                 315                 320


Glu Gly Ala Lys Gln Met Phe Ser Asn Leu Ala Lys Gly Ser Lys 
                325                 330                 335


<210>  7798
<211>  2263
<212>  DNA
<213>  Homo sapiens

<400>  7798
cttcccccct gagtctttcg gcctgggtgg aggacgcggc tgcttcaagt ccttggctct     60

gatccaggcc acagattcca ggattctaca ggcaggaaac atcttagaaa tcagggttgg    120

gcaggcagga gccaggagag tagctacaat gacttcacca gtactggtgg acatacgaga    180

agaggtgacc tgccctatct gcctggagct cctaacagaa cccctgagca tagactgtgg    240

ccacagcttc tgccaagcct gcatcacacc aaatggcagg gaatcagtga ttggtcaaga    300

aggggaaaga agctgccctg tgtgccagac cagctaccag ccagggaacc tgcggcctaa    360

tcggcatctg gccaacatag tgaggcggct cagagaggta gtgttgggcc ctgggaagca    420

gctgaaagca gttctttgtg cagaccatgg agaaaaactg cagctcttct gtcaggagga    480

tgggaaggtc atttgctggc tttgtgagcg gtctcaggag caccgtggtc accacacgtt    540

cctcgtggag gaggttgccc aggagtacca ggagaagttt caggagtctc taaagaagct    600

gaagaacgag gagcaggaag ctgagaagct aacagctttt atcagagaga agaaaacatc    660

ctggaagaat cagatggagc ctgagagatg caggatccag acagagttta atcagctgcg    720

aaatatccta gacagagtgg agcaacggga gctgaaaaag ctggaacagg aagagaagaa    780

ggggctacga attatagaag aggctgagaa tgatctggtc caccagaccc agtcgctgcg    840

agagctcatc tcggatctgg agcgtcgatg tcaggggtca acaatggagc tgctgcagga    900

tgtgagtgat gtcacagaaa ggagtgagtt ctggaccctg aggaagccag aagctctccc    960

tacaaagctg agaagtatgt tccgagcccc agatctgaaa aggatgctgc gagtgtgtag   1020

agagctgaca gatgtccaaa gctactgggt tgacgtgacc ctgaatccac acacagctaa   1080

tttaaatctt gtcctggcta aaaaccggag acaagtgagg tttgtgggag ctaaagtatc   1140

tggaccttcc tgtctggaaa agcattatga ctgtagtgtc ctgggctccc agcacttctc   1200

ctctggtaag cattactggg aggtagatgt ggccaagaag actgcctgga tcctgggggt   1260

atgcagcaat tcactgggac ctacattctc tttcaaccat tttgctcaaa atcacagtgc   1320

ttactccagg tatcagcctc agagtggata ctgggtgatt gggttacagc ataaccatga   1380

atatagggcc tatgaggatt cttccccttc cctgcttctc tccatgacag tgccccctcg   1440

ccgtgttggg gttttcttag attatgaggc tggtactgtc tccttttata atgtcacaaa   1500

ccatggcttc cccatctaca ctttctctaa atattacttt cccactactc tttgtccata   1560

ttttaatcct tgcaactgtg taattcctat gaccctgcgt cgtccaagct cttgaatatt   1620

cttctgttcc cacccacttc tgataagtac cctgaggctt atcagcatgt gattctccct   1680

tctgatcttc tgtttttctg tgttctcaaa cagttctttc gttttaaaca gttactcagt   1740

actaggatgc acccataaaa tgcaataata agcaaataaa ttactttgtt tttgtataag   1800

tatgtatagg attgagctct aaaaccaaac cattataatg ataatttggg tagcttcaaa   1860

ctcaaattga agagagtctt cactacaatc ttcactacaa cctttggcct tcctctctac   1920

atttaagagt agcaatagaa caataaaaaa aaatacgtct ttcaaattaa ttgcagtaaa   1980

aacaaaagag tagtggggag agaaaaacaa tccaatacat atttttctct cagaatagaa   2040

agaaaacaca aagagaaaat atgaacaata taaagcactt aaaggaagag gatgatttct   2100

tccagctttt ccacactctc tttatgcgca ggaacaaaca gctgttgagt gagctgctat   2160

gactttggta gagaggtgca atatgttttt tgaaccagct ataaaagaaa ttaagaggta   2220

catgtgaggg tagaaacaaa tatcaaggat gagaatggca ctg                     2263


<210>  7799
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7799

Met Thr Ser Pro Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His 
            20                  25                  30


Ser Phe Cys Gln Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile 
        35                  40                  45


Gly Gln Glu Gly Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln 
    50                  55                  60


Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg 
65                  70                  75                  80


Leu Arg Glu Val Val Leu Gly Pro Gly Lys Gln Leu Lys Ala Val Leu 
                85                  90                  95


Cys Ala Asp His Gly Glu Lys Leu Gln Leu Phe Cys Gln Glu Asp Gly 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Phe Leu Val Glu Glu Val Ala Gln Glu Tyr Gln Glu Lys Phe 
    130                 135                 140


Gln Glu Ser Leu Lys Lys Leu Lys Asn Glu Glu Gln Glu Ala Glu Lys 
145                 150                 155                 160


Leu Thr Ala Phe Ile Arg Glu Lys Lys Thr Ser Trp Lys Asn Gln Met 
                165                 170                 175


Glu Pro Glu Arg Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg Asn 
            180                 185                 190


Ile Leu Asp Arg Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln Glu 
        195                 200                 205


Glu Lys Lys Gly Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu Val 
    210                 215                 220


His Gln Thr Gln Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg Arg 
225                 230                 235                 240


Cys Gln Gly Ser Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val Thr 
                245                 250                 255


Glu Arg Ser Glu Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro Thr 
            260                 265                 270


Lys Leu Arg Ser Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg 
        275                 280                 285


Val Cys Arg Glu Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val Thr 
    290                 295                 300


Leu Asn Pro His Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn Arg 
305                 310                 315                 320


Arg Gln Val Arg Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys Leu 
                325                 330                 335


Glu Lys His Tyr Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser Ser 
            340                 345                 350


Gly Lys His Tyr Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp Ile 
        355                 360                 365


Leu Gly Val Cys Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn His 
    370                 375                 380


Phe Ala Gln Asn His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser Gly 
385                 390                 395                 400


Tyr Trp Val Ile Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr Glu 
                405                 410                 415


Asp Ser Ser Pro Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg Arg 
            420                 425                 430


Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr Asn 
        435                 440                 445


Val Thr Asn His Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr Phe 
    450                 455                 460


Pro Thr Thr Leu Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile Pro 
465                 470                 475                 480


Met Thr Leu Arg Arg Pro Ser Ser 
                485


<210>  7800
<211>  2488
<212>  DNA
<213>  Homo sapiens

<400>  7800
cttcccccct gagtctttcg gcctgggtgg aggacgcggc tgcttcaagt ccttggctct     60

gatccaggcc acagattcca ggattctaca ggcaggaaac atcttagaaa tcagggttgg    120

gcaggcagga gccaggagag tagctacaat gacttcacca gtactggtgg acatacgaga    180

agaggtgacc tgccctatct gcctggagct cctaacagaa cccctgagca tagactgtgg    240

ccacagcttc tgccaagcct gcatcacacc aaatggcagg gaatcagtga ttggtcaaga    300

aggggaaaga agctgccctg tgtgccagac cagctaccag ccagggaacc tgcggcctaa    360

tcggcatctg gccaacatag tgaggcggct cagagaggta gtgttgggcc ctgggaagca    420

gctgaaagca gttctttgtg cagaccatgg agaaaaactg cagctcttct gtcaggagga    480

tgggaaggtc atttgctggc tttgtgagcg gtctcaggag caccgtggtc accacacgtt    540

cctcgtggag gaggttgccc aggagtacca ggagaagttt caggagtctc taaagaagct    600

gaagaacgag gagcaggaag ctgagaagct aacagctttt atcagagaga agaaaacatc    660

ctggaagaat cagatggagc ctgagagatg caggatccag acagagttta atcagctgcg    720

aaatatccta gacagagtgg agcaacggga gctgaaaaag ctggaacagg aagagaagaa    780

ggggctacga attatagaag aggctgagaa tgatctggtc caccagaccc agtcgctgcg    840

agagctcatc tcggatctgg agcgtcgatg tcaggggtca acaatggagc tgctgcagga    900

tgtgagtgat gtcacagaaa ggagtgagtt ctggaccctg aggaagccag aagctctccc    960

tacaaagctg agaagtatgt tccgagcccc agatctgaaa aggatgctgc gagtgtgtag   1020

agagctgaca gatgtccaaa gctactgggt tgacgtgacc ctgaatccac acacagctaa   1080

tttaaatctt gtcctggcta aaaaccggag acaagtgagg tttgtgggag ctaaagtatc   1140

tggaccttcc tgtctggaaa agcattatga ctgtagtgtc ctgggctccc agcacttctc   1200

ctctggtaag cattactggg aggtagatgt ggccaagaag actgcctgga tcctgggggt   1260

atgcagcaat tcactgggac ctacattctc tttcaaccat tttgctcaaa atcacagtgc   1320

ttactccagg tatcagcctc agagtggata ctgggtgatt gggttacagc ataaccatga   1380

atatagggcc tatgaggatt cttccccttc cctgcttctc tccatgacag tgccccctcg   1440

ccgtgttggg gttttcttag attatgaggc tggtactgtc tccttttata atgtcacaaa   1500

ccatggcttc cccatctaca ctttctctaa atattacttt cccactactc tttgtccata   1560

ttttaatcct tgcaactgtg taattcctat gaccctgcgt cgtccaagct cttgaatatt   1620

cttctgttcc cacccacttc tgataagtac cctgaggctt atcagcatgt gattctccct   1680

tctgatcttc tgtttttctg tgttctcaaa cagttctttc gttttaaaca gttactcagt   1740

actaggatgc acccataaaa tgcaataata agcaaataaa ttactttgtt tttgtataag   1800

tatgtatagg attgagctct aaaaccaaac cattataatg ataatttggg tagcttcaaa   1860

ctcaaattga agagagtctt cactacaatc ttcactacaa cctttggcct tcctctctac   1920

atttaagagt agcaatagaa caataaaaaa aaatacgtct ttcaaattaa ttgcagtaaa   1980

aacaaaagag tagtggggag agaaaaacaa tccaatacat atttttctct cagaatagaa   2040

agaaaacaca aagagaaaat atgaacaata taaagcactt aaaggaagag gatgatttct   2100

tccagctttt ccacactctc tttatgcgca ggaacaaaca gctgttgagt gagctgctat   2160

gactttggta gagaggtgca atatgttttt tgaaccagct ataaaagaaa ttaagaggta   2220

catgtgaggg tagaaacaaa tatcaaggat gagaatggca ctggctgtcc catatggtat   2280

ccaggagcca ccaatgtctg ttgagtactt catacatgcc tagtctgaat tgagatgtgc   2340

tcaatgtata aaatatatac cagatttcaa atacctactt caaaaaataa tgtaaaatat   2400

ctcactaata acttttcctt tgtgtattgc aatgataata tgttggctct attggattaa   2460

ataaagtatg ttattcattt tacctgtt                                      2488


<210>  7801
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7801

Met Thr Ser Pro Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His 
            20                  25                  30


Ser Phe Cys Gln Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile 
        35                  40                  45


Gly Gln Glu Gly Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln 
    50                  55                  60


Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg 
65                  70                  75                  80


Leu Arg Glu Val Val Leu Gly Pro Gly Lys Gln Leu Lys Ala Val Leu 
                85                  90                  95


Cys Ala Asp His Gly Glu Lys Leu Gln Leu Phe Cys Gln Glu Asp Gly 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Phe Leu Val Glu Glu Val Ala Gln Glu Tyr Gln Glu Lys Phe 
    130                 135                 140


Gln Glu Ser Leu Lys Lys Leu Lys Asn Glu Glu Gln Glu Ala Glu Lys 
145                 150                 155                 160


Leu Thr Ala Phe Ile Arg Glu Lys Lys Thr Ser Trp Lys Asn Gln Met 
                165                 170                 175


Glu Pro Glu Arg Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg Asn 
            180                 185                 190


Ile Leu Asp Arg Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln Glu 
        195                 200                 205


Glu Lys Lys Gly Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu Val 
    210                 215                 220


His Gln Thr Gln Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg Arg 
225                 230                 235                 240


Cys Gln Gly Ser Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val Thr 
                245                 250                 255


Glu Arg Ser Glu Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro Thr 
            260                 265                 270


Lys Leu Arg Ser Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg 
        275                 280                 285


Val Cys Arg Glu Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val Thr 
    290                 295                 300


Leu Asn Pro His Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn Arg 
305                 310                 315                 320


Arg Gln Val Arg Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys Leu 
                325                 330                 335


Glu Lys His Tyr Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser Ser 
            340                 345                 350


Gly Lys His Tyr Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp Ile 
        355                 360                 365


Leu Gly Val Cys Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn His 
    370                 375                 380


Phe Ala Gln Asn His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser Gly 
385                 390                 395                 400


Tyr Trp Val Ile Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr Glu 
                405                 410                 415


Asp Ser Ser Pro Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg Arg 
            420                 425                 430


Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr Asn 
        435                 440                 445


Val Thr Asn His Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr Phe 
    450                 455                 460


Pro Thr Thr Leu Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile Pro 
465                 470                 475                 480


Met Thr Leu Arg Arg Pro Ser Ser 
                485


<210>  7802
<211>  2382
<212>  DNA
<213>  Homo sapiens

<400>  7802
ggaggacgcg gctgcttcaa gtccttggct ctgatccagg ccacagattc caggattcta     60

caggcaggaa acatcttaga aatcagggtt gggcaggcag gagccaggag agtagctaca    120

atgacttcac cagtactggt ggacatacga gaagaggtga cctgccctat ctgcctggag    180

ctcctaacag aacccctgag catagactgt ggccacagct tctgccaagc ctgcatcaca    240

ccaaatggca gggaatcagt gattggtcaa gaaggggaaa gaagctgccc tgtgtgccag    300

accagctacc agccagggaa cctgcggcct aatcggcatc tggccaacat agtgaggcgg    360

ctcagagagg aggatgggaa ggtcatttgc tggctttgtg agcggtctca ggagcaccgt    420

ggtcaccaca cgttcctcgt ggaggaggtt gcccaggagt accaggagaa gtttcaggag    480

tctctaaaga agctgaagaa cgaggagcag gaagctgaga agctaacagc ttttatcaga    540

gagaagaaaa catcctggaa gaatcagatg gagcctgaga gatgcaggat ccagacagag    600

tttaatcagc tgcgaaatat cctagacaga gtggagcaac gggagctgaa aaagctggaa    660

caggaagaga agaaggggct acgaattata gaagaggctg agaatgatct ggtccaccag    720

acccagtcgc tgcgagagct catctcggat ctggagcgtc gatgtcaggg gtcaacaatg    780

gagctgctgc aggatgtgag tgatgtcaca gaaaggagtg agttctggac cctgaggaag    840

ccagaagctc tccctacaaa gctgagaagt atgttccgag ccccagatct gaaaaggatg    900

ctgcgagtgt gtagagagct gacagatgtc caaagctact gggttgacgt gaccctgaat    960

ccacacacag ctaatttaaa tcttgtcctg gctaaaaacc ggagacaagt gaggtttgtg   1020

ggagctaaag tatctggacc ttcctgtctg gaaaagcatt atgactgtag tgtcctgggc   1080

tcccagcact tctcctctgg taagcattac tgggaggtag atgtggccaa gaagactgcc   1140

tggatcctgg gggtatgcag caattcactg ggacctacat tctctttcaa ccattttgct   1200

caaaatcaca gtgcttactc caggtatcag cctcagagtg gatactgggt gattgggtta   1260

cagcataacc atgaatatag ggcctatgag gattcttccc cttccctgct tctctccatg   1320

acagtgcccc ctcgccgtgt tggggttttc ttagattatg aggctggtac tgtctccttt   1380

tataatgtca caaaccatgg cttccccatc tacactttct ctaaatatta ctttcccact   1440

actctttgtc catattttaa tccttgcaac tgtgtaattc ctatgaccct gcgtcgtcca   1500

agctcttgaa tattcttctg ttcccaccca cttctgataa gtaccctgag gcttatcagc   1560

atgtgattct cccttctgat cttctgtttt tctgtgttct caaacagttc tttcgtttta   1620

aacagttact cagtactagg atgcacccat aaaatgcaat aataagcaaa taaattactt   1680

tgtttttgta taagtatgta taggattgag ctctaaaacc aaaccattat aatgataatt   1740

tgggtagctt caaactcaaa ttgaagagag tcttcactac aatcttcact acaacctttg   1800

gccttcctct ctacatttaa gagtagcaat agaacaataa aaaaaaatac gtctttcaaa   1860

ttaattgcag taaaaacaaa agagtagtgg ggagagaaaa acaatccaat acatattttt   1920

ctctcagaat agaaagaaaa cacaaagaga aaatatgaac aatataaagc acttaaagga   1980

agaggatgat ttcttccagc ttttccacac tctctttatg cgcaggaaca aacagctgtt   2040

gagtgagctg ctatgacttt ggtagagagg tgcaatatgt tttttgaacc agctataaaa   2100

gaaattaaga ggtacatgtg agggtagaaa caaatatcaa ggatgagaat ggcactggct   2160

gtcccatatg gtatccagga gccaccaatg tctgttgagt acttcataca tgcctagtct   2220

gaattgagat gtgctcaatg tataaaatat ataccagatt tcaaatacct acttcaaaaa   2280

ataatgtaaa atatctcact aataactttt cctttgtgta ttgcaatgat aatatgttgg   2340

ctctattgga ttaaataaag tatgttattc attttacctg tt                      2382


<210>  7803
<211>  462
<212>  PRT
<213>  Homo sapiens

<400>  7803

Met Thr Ser Pro Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His 
            20                  25                  30


Ser Phe Cys Gln Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile 
        35                  40                  45


Gly Gln Glu Gly Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln 
    50                  55                  60


Pro Gly Asn Leu Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg 
65                  70                  75                  80


Leu Arg Glu Glu Asp Gly Lys Val Ile Cys Trp Leu Cys Glu Arg Ser 
                85                  90                  95


Gln Glu His Arg Gly His His Thr Phe Leu Val Glu Glu Val Ala Gln 
            100                 105                 110


Glu Tyr Gln Glu Lys Phe Gln Glu Ser Leu Lys Lys Leu Lys Asn Glu 
        115                 120                 125


Glu Gln Glu Ala Glu Lys Leu Thr Ala Phe Ile Arg Glu Lys Lys Thr 
    130                 135                 140


Ser Trp Lys Asn Gln Met Glu Pro Glu Arg Cys Arg Ile Gln Thr Glu 
145                 150                 155                 160


Phe Asn Gln Leu Arg Asn Ile Leu Asp Arg Val Glu Gln Arg Glu Leu 
                165                 170                 175


Lys Lys Leu Glu Gln Glu Glu Lys Lys Gly Leu Arg Ile Ile Glu Glu 
            180                 185                 190


Ala Glu Asn Asp Leu Val His Gln Thr Gln Ser Leu Arg Glu Leu Ile 
        195                 200                 205


Ser Asp Leu Glu Arg Arg Cys Gln Gly Ser Thr Met Glu Leu Leu Gln 
    210                 215                 220


Asp Val Ser Asp Val Thr Glu Arg Ser Glu Phe Trp Thr Leu Arg Lys 
225                 230                 235                 240


Pro Glu Ala Leu Pro Thr Lys Leu Arg Ser Met Phe Arg Ala Pro Asp 
                245                 250                 255


Leu Lys Arg Met Leu Arg Val Cys Arg Glu Leu Thr Asp Val Gln Ser 
            260                 265                 270


Tyr Trp Val Asp Val Thr Leu Asn Pro His Thr Ala Asn Leu Asn Leu 
        275                 280                 285


Val Leu Ala Lys Asn Arg Arg Gln Val Arg Phe Val Gly Ala Lys Val 
    290                 295                 300


Ser Gly Pro Ser Cys Leu Glu Lys His Tyr Asp Cys Ser Val Leu Gly 
305                 310                 315                 320


Ser Gln His Phe Ser Ser Gly Lys His Tyr Trp Glu Val Asp Val Ala 
                325                 330                 335


Lys Lys Thr Ala Trp Ile Leu Gly Val Cys Ser Asn Ser Leu Gly Pro 
            340                 345                 350


Thr Phe Ser Phe Asn His Phe Ala Gln Asn His Ser Ala Tyr Ser Arg 
        355                 360                 365


Tyr Gln Pro Gln Ser Gly Tyr Trp Val Ile Gly Leu Gln His Asn His 
    370                 375                 380


Glu Tyr Arg Ala Tyr Glu Asp Ser Ser Pro Ser Leu Leu Leu Ser Met 
385                 390                 395                 400


Thr Val Pro Pro Arg Arg Val Gly Val Phe Leu Asp Tyr Glu Ala Gly 
                405                 410                 415


Thr Val Ser Phe Tyr Asn Val Thr Asn His Gly Phe Pro Ile Tyr Thr 
            420                 425                 430


Phe Ser Lys Tyr Tyr Phe Pro Thr Thr Leu Cys Pro Tyr Phe Asn Pro 
        435                 440                 445


Cys Asn Cys Val Ile Pro Met Thr Leu Arg Arg Pro Ser Ser 
    450                 455                 460


<210>  7804
<211>  591
<212>  DNA
<213>  Homo sapiens

<400>  7804
ccagaaggag ttgggagatg agccttccgc aaactcctga cctgtgggtc cgtccgttca     60

acggccaaag gctggcggag gagggatccc ctgcctttct cggaacggaa cggagcagag    120

tcgtgcgtgg ttgagtttag ataaaagccg agtgagcgcg ctctgttcct taagattagt    180

ttaaggtgcc ttggattgct ctgaagagct ttgaccacct gatattgctt acatctggaa    240

cttcttggct tctcattccc cagatgtgcg ggtcagagag gattctacag gcaggaaaca    300

tcttagaaat cagggttggg caggcaggag ccaggagagt agctacaatg acttcaccag    360

tactggtgga catacgagaa gaggtgacct gccctatctg cctggagctc ctaacagaac    420

ccctgagcat agactgtggc cacagcttct gccaagcctg catcacacca aatggcaggg    480

aatcagtgat tggtcaagaa ggggaaagaa gctgccctgt gtgccagacc agctaccagc    540

cagggaacct gcggcctaat cggcatctgg ccaacatagt gaggcggctc a             591


<210>  7805
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  7805

Met Cys Gly Ser Glu Arg Ile Leu Gln Ala Gly Asn Ile Leu Glu Ile 
1               5                   10                  15


Arg Val Gly Gln Ala Gly Ala Arg Arg Val Ala Thr Met Thr Ser Pro 
            20                  25                  30


Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro Ile Cys Leu Glu 
        35                  40                  45


Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His Ser Phe Cys Gln 
    50                  55                  60


Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile Gly Gln Glu Gly 
65                  70                  75                  80


Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln Pro Gly Asn Leu 
                85                  90                  95


Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg 
            100                 105


<210>  7806
<211>  2594
<212>  DNA
<213>  Homo sapiens

<400>  7806
gagccttccg caaactcctg acctgtgggt ccgtccgttc aacggccaaa ggctggcgga     60

ggagggatcc cctgcctttc tcggaacgga acggagcaga gtcgtgcgtg gttgagttta    120

gataaaagcc gagtgagcgc gctctgttcc ttaagattag tttaaggtgc cttggattgc    180

tctgaagagc tttgaccacc tgatattgct tacatctgga acttcttggc ttctcattcc    240

ccagatgtgc gggtcagaga ggatgtgagt gatgtcacag aaaggagtga gttctggacc    300

ctgaggaagc cagaagctct ccctacaaag ctgagaagta tgttccgagc cccagatctg    360

aaaaggatgc tgcgagtgtg tagagagctg acagatgtcc aaagctactg ggttgacgtg    420

accctgaatc cacacacagc taatttaaat cttgtcctgg ctaaaaaccg gagacaagtg    480

aggtttgtgg gagctaaagt atctggacct tcctgtctgg aaaagcatta tgactgtagt    540

gtcctgggct cccagcactt ctcctctggt aagcattact gggaggtaga tgtggccaag    600

aagactgcct ggatcctggg ggtatgcagc aattcactgg gacctacatt ctctttcaac    660

cattttgctc aaaatcacag tgcttactcc aggtatcagc ctcagagtgg atactgggtg    720

attgggttac agcataacca tgaatatagg gcctatgagg attcttcccc ttccctgctt    780

ctctccatga cagtgccccc tcgccgtgtt ggggttttct tagattatga ggctggtact    840

gtctcctttt ataatgtcac aaaccatggc ttccccatct acactttctc taaatattac    900

tttcccacta ctctttgtcc atattttaat ccttgcaact gtgtaattcc tatgaccctg    960

cgtcgtccaa gctcttgaat attcttctgt tcccacccac ttctgataag taccctgagg   1020

cttatcagca tgtgattctc ccttctgatc ttctgttttt ctgtgttctc aattcttttg   1080

ttgttttttg gtttttgaat cttttttgag atggaatctc gctctgtcgc ccaggctgga   1140

gtgcactggc gcaatctcgg ctcactgcaa cctctgcctc ctgggttcaa gcgaacctcc   1200

tgcctcagca tcccaagtag ctgggattac aggcacccac caccatgccc aactaatttt   1260

tgtattttta tagagatagg gtttcaccgt gttggccagg ctgatctcga actcctgacc   1320

gcaagtgatc cacccgcctc ggtctcccaa agtgctggga ttacagatgt gagccgccgc   1380

gcccagacag ttctttcgtt ttaaacagtt actcagtact aggatgcacc cagtggtgag   1440

agtaagcatc tttgactgat gacaggtctt gaggtggata gggggcgctt tcagtatttt   1500

gccattaagc atagtatttg atgcaggttt tttttgattg atgcagggga tcaaatttag   1560

gaagttctga tctgttaatt tactacaagt ttttgtataa aatgaaaact cgtattctac   1620

ctatgtcttt tctgtaaatt attgagacaa ttgtgtatca tttttgttct gttaatgtgg   1680

cttagtacat tgatttactt caatttgtta ccacaacttg ctgaaataca ccattattat   1740

ttgttgtatg caatactgga tttattttga taacgtattg tttagatttt gttctcatct   1800

atgttaatga aagaaattgg cctgtatttt tacattcttg taatatcttt gccaggttct   1860

ataaaatgca ataataagca aataaattac tttgtttttg tataagtatg tataggattg   1920

agctctaaaa ccaaaccatt ataatgataa tttgggtagc ttcaaactca aattgaagag   1980

agtcttcact acaatcttca ctacaacctt tggccttcct ctctacattt aagagtagca   2040

atagaacaat aaaaaaaaat acgtctttca aattaattgc agtaaaaaca aaagagtagt   2100

ggggagagaa aaacaatcca atacatattt ttctctcaga atagaaagaa aacacaaaga   2160

gaaaatatga acaatataaa gcacttaaag gaagaggatg atttcttcca gcttttccac   2220

actctcttta tgcgcaggaa caaacagctg ttgagtgagc tgctatgact ttggtagaga   2280

ggtgcaatat gttttttgaa ccagctataa aagaaattaa gaggtacatg tgagggtaga   2340

aacaaatatc aaggatgaga atggcactgg ctgtcccata tggtatccag gagccaccaa   2400

tgtctgttga gtacttcata catgcctagt ctgaattgag atgtgctcaa tgtataaaat   2460

atataccaga tttcaaatac ctacttcaaa aaataatgta aaatatctca ctaataactt   2520

ttcctttgtg tattgcaatg ataatatgtt ggctctattg gattaaataa agtatgttat   2580

tcattttacc tgtt                                                     2594


<210>  7807
<211>  212
<212>  PRT
<213>  Homo sapiens

<400>  7807

Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg Val Cys Arg Glu 
1               5                   10                  15


Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val Thr Leu Asn Pro His 
            20                  25                  30


Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn Arg Arg Gln Val Arg 
        35                  40                  45


Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys Leu Glu Lys His Tyr 
    50                  55                  60


Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser Ser Gly Lys His Tyr 
65                  70                  75                  80


Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp Ile Leu Gly Val Cys 
                85                  90                  95


Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn His Phe Ala Gln Asn 
            100                 105                 110


His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser Gly Tyr Trp Val Ile 
        115                 120                 125


Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr Glu Asp Ser Ser Pro 
    130                 135                 140


Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg Arg Val Gly Val Phe 
145                 150                 155                 160


Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr Asn Val Thr Asn His 
                165                 170                 175


Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr Phe Pro Thr Thr Leu 
            180                 185                 190


Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile Pro Met Thr Leu Arg 
        195                 200                 205


Arg Pro Ser Ser 
    210


<210>  7808
<211>  2441
<212>  DNA
<213>  Homo sapiens

<400>  7808
gccttccgca aactcctgac ctgtgggtcc gtccgttcaa cggccaaagg ctggcggagg     60

agggatcccc tgcctttctc ggaacggaac ggagcagagt cgtgcgtggt tgagtttaga    120

taaaagccga gtgagcgcgc tctgttcctt aagattagtt taaggtgcct tggattgctc    180

tgaagagctt tgaccacctg atattgctta catctggaac ttcttggctt ctcattcccc    240

agatgtgcgg gtcagagagg attctacagg caggaaacat cttagaaatc agggttgggc    300

aggcaggagc caggagagta gctacaatga cttcaccagt actggtggac atacgagaag    360

aggtgacctg ccctatctgc ctggagctcc taacagaacc cctgagcata gactgtggcc    420

acagcttctg ccaagcctgc atcacaccaa atggcaggga atcagtgatt ggtcaagaag    480

gggaaagaag ctgccctgtg tgccagacca gctaccagcc agggaacctg cggcctaatc    540

ggcatctggc caacatagtg aggcggctca gagaggtagt gttgggccct gggaagcagc    600

tgaaagcagt tctttgtgca gaccatggag aaaaactgca gctcttctgt caggaggatg    660

ggaaggtcat ttgctggctt tgtgagcggt ctcaggagca ccgtggtcac cacacgttcc    720

tcgtggagga ggttgcccag gagtaccagg agaagtttca ggagtctcta aagaagctga    780

agaacgagga gcaggaagct gagaagctaa cagcttttat cagagagaag aaaacatcct    840

ggaagaatca gatggagcct gagagatgca ggatccagac agagtttaat cagctgcgaa    900

atatcctaga cagagtggag caacgggagc tgaaaaagct ggaacaggaa gagaagaagg    960

ggctacgaat tatagaagag gctgagaatg atctggtcca ccagacccag tcgctgcgag   1020

agctcatctc ggatctggag cgtcgatgtc aggggtcaac aatggagctg ctgcaggatg   1080

tgagtgatgt cacagaaagg agtgagttct ggaccctgag gaagccagaa gctctcccta   1140

caaagctgag aagtatgttc cgagccccag atctgaaaag gatgctgcga gtgtgtagag   1200

agctgacaga tgtccaaagc tactgggttg acgtgaccct gaatccacac acagctaatt   1260

taaatcttgt cctggctaaa aaccggagac aagtgaggtt tgtgggagct aaagtatctg   1320

gaccttcctg tctggaaaag cattatgact gtagtgtcct gggctcccag cacttctcct   1380

ctggtaagca ttactgggag gtagatgtgg ccaagaagac tgcctggatc ctgggggtat   1440

gcagcaattc actgggacct acattctctt tcaaccattt tgctcaaaat cacagtgctt   1500

actccaggta tcagcctcag agtggatact gggtgattgg gttacagcat aaccatgaat   1560

atagggccta tgaggattct tccccttccc tgcttctctc catgacagtg ccccctcgcc   1620

gtgttggggt tttcttagat tatgaggctg gtactgtctc cttttataat gtcacaaacc   1680

atggcttccc catctacact ttctctaaat attactttcc cactactctt tgtccatatt   1740

ttaatccttg caactgtgta attcctatga ccctgcgtcg tccaagctct tgaatattct   1800

tctgttccca cccacttctg ataagtaccc tgaggcttat cagcatgtga ttctcccttc   1860

tgatcttctg tttttctgtg ttctcaaaca gttctttcgt tttaaacagt tactcagtac   1920

taggatgcac ccataaaatg caataataag caaataaatt actttgtttt tgtataagta   1980

tgtataggat tgagctctaa aaccaaacca ttataatgat aatttgggta gcttcaaact   2040

caaattgaag agagtcttca ctacaatctt cactacaacc tttggccttc ctctctacat   2100

ttaagagtag caatagaaca ataaaaaaaa atacgtcttt caaattaatt gcagtaaaaa   2160

caaaagagta gtggggagag aaaaacaatc caatacatat ttttctctca gaatagaaag   2220

aaaacacaaa gagaaaatat gaacaatata aagcacttaa aggaagagga tgatttcttc   2280

cagcttttcc acactctctt tatgcgcagg aacaaacagc tgttgagtga gctgctatga   2340

ctttggtaga gaggtgcaat atgttttttg aaccagctat aaaagaaatt aagaggtaca   2400

tgtgagggta gaaacaaata tcaaggatga gaatggcact g                       2441


<210>  7809
<211>  516
<212>  PRT
<213>  Homo sapiens

<400>  7809

Met Cys Gly Ser Glu Arg Ile Leu Gln Ala Gly Asn Ile Leu Glu Ile 
1               5                   10                  15


Arg Val Gly Gln Ala Gly Ala Arg Arg Val Ala Thr Met Thr Ser Pro 
            20                  25                  30


Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro Ile Cys Leu Glu 
        35                  40                  45


Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His Ser Phe Cys Gln 
    50                  55                  60


Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile Gly Gln Glu Gly 
65                  70                  75                  80


Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln Pro Gly Asn Leu 
                85                  90                  95


Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg Leu Arg Glu Val 
            100                 105                 110


Val Leu Gly Pro Gly Lys Gln Leu Lys Ala Val Leu Cys Ala Asp His 
        115                 120                 125


Gly Glu Lys Leu Gln Leu Phe Cys Gln Glu Asp Gly Lys Val Ile Cys 
    130                 135                 140


Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His His Thr Phe Leu 
145                 150                 155                 160


Val Glu Glu Val Ala Gln Glu Tyr Gln Glu Lys Phe Gln Glu Ser Leu 
                165                 170                 175


Lys Lys Leu Lys Asn Glu Glu Gln Glu Ala Glu Lys Leu Thr Ala Phe 
            180                 185                 190


Ile Arg Glu Lys Lys Thr Ser Trp Lys Asn Gln Met Glu Pro Glu Arg 
        195                 200                 205


Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg Asn Ile Leu Asp Arg 
    210                 215                 220


Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln Glu Glu Lys Lys Gly 
225                 230                 235                 240


Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu Val His Gln Thr Gln 
                245                 250                 255


Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg Arg Cys Gln Gly Ser 
            260                 265                 270


Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val Thr Glu Arg Ser Glu 
        275                 280                 285


Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro Thr Lys Leu Arg Ser 
    290                 295                 300


Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg Val Cys Arg Glu 
305                 310                 315                 320


Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val Thr Leu Asn Pro His 
                325                 330                 335


Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn Arg Arg Gln Val Arg 
            340                 345                 350


Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys Leu Glu Lys His Tyr 
        355                 360                 365


Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser Ser Gly Lys His Tyr 
    370                 375                 380


Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp Ile Leu Gly Val Cys 
385                 390                 395                 400


Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn His Phe Ala Gln Asn 
                405                 410                 415


His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser Gly Tyr Trp Val Ile 
            420                 425                 430


Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr Glu Asp Ser Ser Pro 
        435                 440                 445


Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg Arg Val Gly Val Phe 
    450                 455                 460


Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr Asn Val Thr Asn His 
465                 470                 475                 480


Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr Phe Pro Thr Thr Leu 
                485                 490                 495


Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile Pro Met Thr Leu Arg 
            500                 505                 510


Arg Pro Ser Ser 
        515


<210>  7810
<211>  2666
<212>  DNA
<213>  Homo sapiens

<400>  7810
gccttccgca aactcctgac ctgtgggtcc gtccgttcaa cggccaaagg ctggcggagg     60

agggatcccc tgcctttctc ggaacggaac ggagcagagt cgtgcgtggt tgagtttaga    120

taaaagccga gtgagcgcgc tctgttcctt aagattagtt taaggtgcct tggattgctc    180

tgaagagctt tgaccacctg atattgctta catctggaac ttcttggctt ctcattcccc    240

agatgtgcgg gtcagagagg attctacagg caggaaacat cttagaaatc agggttgggc    300

aggcaggagc caggagagta gctacaatga cttcaccagt actggtggac atacgagaag    360

aggtgacctg ccctatctgc ctggagctcc taacagaacc cctgagcata gactgtggcc    420

acagcttctg ccaagcctgc atcacaccaa atggcaggga atcagtgatt ggtcaagaag    480

gggaaagaag ctgccctgtg tgccagacca gctaccagcc agggaacctg cggcctaatc    540

ggcatctggc caacatagtg aggcggctca gagaggtagt gttgggccct gggaagcagc    600

tgaaagcagt tctttgtgca gaccatggag aaaaactgca gctcttctgt caggaggatg    660

ggaaggtcat ttgctggctt tgtgagcggt ctcaggagca ccgtggtcac cacacgttcc    720

tcgtggagga ggttgcccag gagtaccagg agaagtttca ggagtctcta aagaagctga    780

agaacgagga gcaggaagct gagaagctaa cagcttttat cagagagaag aaaacatcct    840

ggaagaatca gatggagcct gagagatgca ggatccagac agagtttaat cagctgcgaa    900

atatcctaga cagagtggag caacgggagc tgaaaaagct ggaacaggaa gagaagaagg    960

ggctacgaat tatagaagag gctgagaatg atctggtcca ccagacccag tcgctgcgag   1020

agctcatctc ggatctggag cgtcgatgtc aggggtcaac aatggagctg ctgcaggatg   1080

tgagtgatgt cacagaaagg agtgagttct ggaccctgag gaagccagaa gctctcccta   1140

caaagctgag aagtatgttc cgagccccag atctgaaaag gatgctgcga gtgtgtagag   1200

agctgacaga tgtccaaagc tactgggttg acgtgaccct gaatccacac acagctaatt   1260

taaatcttgt cctggctaaa aaccggagac aagtgaggtt tgtgggagct aaagtatctg   1320

gaccttcctg tctggaaaag cattatgact gtagtgtcct gggctcccag cacttctcct   1380

ctggtaagca ttactgggag gtagatgtgg ccaagaagac tgcctggatc ctgggggtat   1440

gcagcaattc actgggacct acattctctt tcaaccattt tgctcaaaat cacagtgctt   1500

actccaggta tcagcctcag agtggatact gggtgattgg gttacagcat aaccatgaat   1560

atagggccta tgaggattct tccccttccc tgcttctctc catgacagtg ccccctcgcc   1620

gtgttggggt tttcttagat tatgaggctg gtactgtctc cttttataat gtcacaaacc   1680

atggcttccc catctacact ttctctaaat attactttcc cactactctt tgtccatatt   1740

ttaatccttg caactgtgta attcctatga ccctgcgtcg tccaagctct tgaatattct   1800

tctgttccca cccacttctg ataagtaccc tgaggcttat cagcatgtga ttctcccttc   1860

tgatcttctg tttttctgtg ttctcaaaca gttctttcgt tttaaacagt tactcagtac   1920

taggatgcac ccataaaatg caataataag caaataaatt actttgtttt tgtataagta   1980

tgtataggat tgagctctaa aaccaaacca ttataatgat aatttgggta gcttcaaact   2040

caaattgaag agagtcttca ctacaatctt cactacaacc tttggccttc ctctctacat   2100

ttaagagtag caatagaaca ataaaaaaaa atacgtcttt caaattaatt gcagtaaaaa   2160

caaaagagta gtggggagag aaaaacaatc caatacatat ttttctctca gaatagaaag   2220

aaaacacaaa gagaaaatat gaacaatata aagcacttaa aggaagagga tgatttcttc   2280

cagcttttcc acactctctt tatgcgcagg aacaaacagc tgttgagtga gctgctatga   2340

ctttggtaga gaggtgcaat atgttttttg aaccagctat aaaagaaatt aagaggtaca   2400

tgtgagggta gaaacaaata tcaaggatga gaatggcact ggctgtccca tatggtatcc   2460

aggagccacc aatgtctgtt gagtacttca tacatgccta gtctgaattg agatgtgctc   2520

aatgtataaa atatatacca gatttcaaat acctacttca aaaaataatg taaaatatct   2580

cactaataac ttttcctttg tgtattgcaa tgataatatg ttggctctat tggattaaat   2640

aaagtatgtt attcatttta cctgtt                                        2666


<210>  7811
<211>  516
<212>  PRT
<213>  Homo sapiens

<400>  7811

Met Cys Gly Ser Glu Arg Ile Leu Gln Ala Gly Asn Ile Leu Glu Ile 
1               5                   10                  15


Arg Val Gly Gln Ala Gly Ala Arg Arg Val Ala Thr Met Thr Ser Pro 
            20                  25                  30


Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro Ile Cys Leu Glu 
        35                  40                  45


Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His Ser Phe Cys Gln 
    50                  55                  60


Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile Gly Gln Glu Gly 
65                  70                  75                  80


Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln Pro Gly Asn Leu 
                85                  90                  95


Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg Leu Arg Glu Val 
            100                 105                 110


Val Leu Gly Pro Gly Lys Gln Leu Lys Ala Val Leu Cys Ala Asp His 
        115                 120                 125


Gly Glu Lys Leu Gln Leu Phe Cys Gln Glu Asp Gly Lys Val Ile Cys 
    130                 135                 140


Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His His Thr Phe Leu 
145                 150                 155                 160


Val Glu Glu Val Ala Gln Glu Tyr Gln Glu Lys Phe Gln Glu Ser Leu 
                165                 170                 175


Lys Lys Leu Lys Asn Glu Glu Gln Glu Ala Glu Lys Leu Thr Ala Phe 
            180                 185                 190


Ile Arg Glu Lys Lys Thr Ser Trp Lys Asn Gln Met Glu Pro Glu Arg 
        195                 200                 205


Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg Asn Ile Leu Asp Arg 
    210                 215                 220


Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln Glu Glu Lys Lys Gly 
225                 230                 235                 240


Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu Val His Gln Thr Gln 
                245                 250                 255


Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg Arg Cys Gln Gly Ser 
            260                 265                 270


Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val Thr Glu Arg Ser Glu 
        275                 280                 285


Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro Thr Lys Leu Arg Ser 
    290                 295                 300


Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg Val Cys Arg Glu 
305                 310                 315                 320


Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val Thr Leu Asn Pro His 
                325                 330                 335


Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn Arg Arg Gln Val Arg 
            340                 345                 350


Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys Leu Glu Lys His Tyr 
        355                 360                 365


Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser Ser Gly Lys His Tyr 
    370                 375                 380


Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp Ile Leu Gly Val Cys 
385                 390                 395                 400


Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn His Phe Ala Gln Asn 
                405                 410                 415


His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser Gly Tyr Trp Val Ile 
            420                 425                 430


Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr Glu Asp Ser Ser Pro 
        435                 440                 445


Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg Arg Val Gly Val Phe 
    450                 455                 460


Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr Asn Val Thr Asn His 
465                 470                 475                 480


Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr Phe Pro Thr Thr Leu 
                485                 490                 495


Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile Pro Met Thr Leu Arg 
            500                 505                 510


Arg Pro Ser Ser 
        515


<210>  7812
<211>  3235
<212>  DNA
<213>  Homo sapiens

<400>  7812
gccttccgca aactcctgac ctgtgggtcc gtccgttcaa cggccaaagg ctggcggagg     60

agggatcccc tgcctttctc ggaacggaac ggagcagagt cgtgcgtggt tgagtttaga    120

taaaagccga gtgagcgcgc tctgttcctt aagattagtt taaggtgcct tggattgctc    180

tgaagagctt tgaccacctg atattgctta catctggaac ttcttggctt ctcattcccc    240

agatgtgcgg gtcagagagg attctacagg caggaaacat cttagaaatc agggttgggc    300

aggcaggagc caggagagta gctacaatga cttcaccagt actggtggac atacgagaag    360

aggtgacctg ccctatctgc ctggagctcc taacagaacc cctgagcata gactgtggcc    420

acagcttctg ccaagcctgc atcacaccaa atggcaggga atcagtgatt ggtcaagaag    480

gggaaagaag ctgccctgtg tgccagacca gctaccagcc agggaacctg cggcctaatc    540

ggcatctggc caacatagtg aggcggctca gagaggtagt gttgggccct gggaagcagc    600

tgaaagcagt tctttgtgca gaccatggag aaaaactgca gctcttctgt caggaggatg    660

ggaaggtcat ttgctggctt tgtgagcggt ctcaggagca ccgtggtcac cacacgttcc    720

tcgtggagga ggttgcccag gagtaccagg agaagtttca ggagtctcta aagaagctga    780

agaacgagga gcaggaagct gagaagctaa cagcttttat cagagagaag aaaacatcct    840

ggaagaatca gatggagcct gagagatgca ggatccagac agagtttaat cagctgcgaa    900

atatcctaga cagagtggag caacgggagc tgaaaaagct ggaacaggaa gagaagaagg    960

ggctacgaat tatagaagag gctgagaatg atctggtcca ccagacccag tcgctgcgag   1020

agctcatctc ggatctggag cgtcgatgtc aggggtcaac aatggagctg ctgcaggatg   1080

tgagtgatgt cacagaaagg agtgagttct ggaccctgag gaagccagaa gctctcccta   1140

caaagctgag aagtatgttc cgagccccag atctgaaaag gatgctgcga gtgtgtagag   1200

agctgacaga tgtccaaagc tactgggcca tccaggggtc tttaaccaga agagagagga   1260

gagcctcagg agttaggacc agaagaagcc agggaagcag tgcaatggct tcaaaaatct   1320

tgcttaacgt acaagaggag gtgacctgtc ccatctgcct ggagctgttg acagaaccct   1380

tgagtctaga ctgtggccac agcctctgcc gagcctgcat cactgtgagc aacaaggagg   1440

cagtgaccag catgggagga aaaagcagct gtcctgtgtg tggtatcagt tactcatttg   1500

aacatctaca ggctaatcag catctggcca acatagtgga gagactcaag gaggtcaagt   1560

tgagcccaga caatgggaag aagagagatc tctgtgatca tcatggagag aaactcctac   1620

tcttctgtaa ggaggatagg aaagtcattt gctggctttg tgagcggtct caggagcacc   1680

gtggtcacca cacagtcctc acggaggaag tattcaagga atgtcaggag aaactccagg   1740

cagtcctcaa gaggctgaag aaggaagagg aggaagctga gaagctggaa gctgacatca   1800

gagaagagaa aacttcctgg aagtatcagg tacaaactga gagacaaagg atacaaacag   1860

aatttgatca gcttagaagc atcctaaata atgaggagca gagagagctg caaagattgg   1920

aagaagaaga aaagaagacg ctggataagt ttgcagaggc tgaggatgag ctagttcagc   1980

agaagcagtt ggtgagagag ctcatctcag atgtggagtg tcggagtcag tggtcaacaa   2040

tggagctgct gcaggacatg agtggaatca tgaaatggag tgagatctgg aggctgaaaa   2100

agccaaaaat ggtttccaag aaactgaaga ctgtattcca tgctccagat ctgagtagga   2160

tgctgcaaat gtttagagaa ctgacagctg tccggtgcta ctgggtggat gtcacactga   2220

attcagtcaa cctaaatttg aatcttgtcc tttcagaaga tcagagacaa gtgatatctg   2280

tgccaatttg gccttttcag tgttataatt atggtgtctt gggatcccaa tatttctcct   2340

ctgggaaaca ttactgggaa gtggacgtgt ccaagaaaac tgcctggatc ctgggggtat   2400

actgtagaac atattcccgc catatgaagt atgttgttag aagatgtgca aatcgtcaaa   2460

atctttacac caaatacaga cctctatttg gctactgggt tatagggtta cagaataaat   2520

gtaagtatgg tgtctttgaa gagtctttgt cctctgatcc cgaggttttg actctctcca   2580

tggctgtgcc tccctgccgt gttggggttt tcctcgacta tgaagcaggc attgtctcat   2640

ttttcaatgt cacaagccat ggctccctca tttacaagtt ctctaaatgt tgcttttctc   2700

agcctgttta tccatatttc aatccttgga actgtccagc tcccatgact ctatgcccac   2760

caagctcttg aattttctca tttcttcacc tacaaccctt tgtcttgact tatctcctgc   2820

aactgactca tctgcaacat tcacaccatt gcttccttgt ggtttccctt ctttagaact   2880

tttactcatc cttgagatgt atggtgtatt tggcttgagt tatgagagat gcttatttat   2940

tcatttactc tttttcatat tttcagagaa agttacctaa tccctcctaa agacacagca   3000

gtatgggtat aacatccttg ccttcccatt tatccatgtt tcactttatc actgatatga   3060

agaggcccaa agcctgttag ccaccatcca tgctacctag gtagtccata ggaaccaccc   3120

ccatgaccac caccaacatc aactaaaggt tcttggaggg tatgtcagtg tgttgctcag   3180

gataccccag gtacatcaag gaatcaagga gaggaaaata tgagcaatat gtgta        3235


<210>  7813
<211>  842
<212>  PRT
<213>  Homo sapiens

<400>  7813

Met Cys Gly Ser Glu Arg Ile Leu Gln Ala Gly Asn Ile Leu Glu Ile 
1               5                   10                  15


Arg Val Gly Gln Ala Gly Ala Arg Arg Val Ala Thr Met Thr Ser Pro 
            20                  25                  30


Val Leu Val Asp Ile Arg Glu Glu Val Thr Cys Pro Ile Cys Leu Glu 
        35                  40                  45


Leu Leu Thr Glu Pro Leu Ser Ile Asp Cys Gly His Ser Phe Cys Gln 
    50                  55                  60


Ala Cys Ile Thr Pro Asn Gly Arg Glu Ser Val Ile Gly Gln Glu Gly 
65                  70                  75                  80


Glu Arg Ser Cys Pro Val Cys Gln Thr Ser Tyr Gln Pro Gly Asn Leu 
                85                  90                  95


Arg Pro Asn Arg His Leu Ala Asn Ile Val Arg Arg Leu Arg Glu Val 
            100                 105                 110


Val Leu Gly Pro Gly Lys Gln Leu Lys Ala Val Leu Cys Ala Asp His 
        115                 120                 125


Gly Glu Lys Leu Gln Leu Phe Cys Gln Glu Asp Gly Lys Val Ile Cys 
    130                 135                 140


Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His His Thr Phe Leu 
145                 150                 155                 160


Val Glu Glu Val Ala Gln Glu Tyr Gln Glu Lys Phe Gln Glu Ser Leu 
                165                 170                 175


Lys Lys Leu Lys Asn Glu Glu Gln Glu Ala Glu Lys Leu Thr Ala Phe 
            180                 185                 190


Ile Arg Glu Lys Lys Thr Ser Trp Lys Asn Gln Met Glu Pro Glu Arg 
        195                 200                 205


Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg Asn Ile Leu Asp Arg 
    210                 215                 220


Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln Glu Glu Lys Lys Gly 
225                 230                 235                 240


Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu Val His Gln Thr Gln 
                245                 250                 255


Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg Arg Cys Gln Gly Ser 
            260                 265                 270


Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val Thr Glu Arg Ser Glu 
        275                 280                 285


Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro Thr Lys Leu Arg Ser 
    290                 295                 300


Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu Arg Val Cys Arg Glu 
305                 310                 315                 320


Leu Thr Asp Val Gln Ser Tyr Trp Ala Ile Gln Gly Ser Leu Thr Arg 
                325                 330                 335


Arg Glu Arg Arg Ala Ser Gly Val Arg Thr Arg Arg Ser Gln Gly Ser 
            340                 345                 350


Ser Ala Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr 
        355                 360                 365


Cys Pro Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys 
    370                 375                 380


Gly His Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala 
385                 390                 395                 400


Val Thr Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser 
                405                 410                 415


Tyr Ser Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val 
            420                 425                 430


Glu Arg Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg 
        435                 440                 445


Asp Leu Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu 
    450                 455                 460


Asp Arg Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg 
465                 470                 475                 480


Gly His His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu 
                485                 490                 495


Lys Leu Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala 
            500                 505                 510


Glu Lys Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr 
        515                 520                 525


Gln Val Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu 
    530                 535                 540


Arg Ser Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu 
545                 550                 555                 560


Glu Glu Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu 
                565                 570                 575


Leu Val Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu 
            580                 585                 590


Cys Arg Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly 
        595                 600                 605


Ile Met Lys Trp Ser Glu Ile Trp Arg Leu Lys Lys Pro Lys Met Val 
    610                 615                 620


Ser Lys Lys Leu Lys Thr Val Phe His Ala Pro Asp Leu Ser Arg Met 
625                 630                 635                 640


Leu Gln Met Phe Arg Glu Leu Thr Ala Val Arg Cys Tyr Trp Val Asp 
                645                 650                 655


Val Thr Leu Asn Ser Val Asn Leu Asn Leu Asn Leu Val Leu Ser Glu 
            660                 665                 670


Asp Gln Arg Gln Val Ile Ser Val Pro Ile Trp Pro Phe Gln Cys Tyr 
        675                 680                 685


Asn Tyr Gly Val Leu Gly Ser Gln Tyr Phe Ser Ser Gly Lys His Tyr 
    690                 695                 700


Trp Glu Val Asp Val Ser Lys Lys Thr Ala Trp Ile Leu Gly Val Tyr 
705                 710                 715                 720


Cys Arg Thr Tyr Ser Arg His Met Lys Tyr Val Val Arg Arg Cys Ala 
                725                 730                 735


Asn Arg Gln Asn Leu Tyr Thr Lys Tyr Arg Pro Leu Phe Gly Tyr Trp 
            740                 745                 750


Val Ile Gly Leu Gln Asn Lys Cys Lys Tyr Gly Val Phe Glu Glu Ser 
        755                 760                 765


Leu Ser Ser Asp Pro Glu Val Leu Thr Leu Ser Met Ala Val Pro Pro 
    770                 775                 780


Cys Arg Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Ile Val Ser Phe 
785                 790                 795                 800


Phe Asn Val Thr Ser His Gly Ser Leu Ile Tyr Lys Phe Ser Lys Cys 
                805                 810                 815


Cys Phe Ser Gln Pro Val Tyr Pro Tyr Phe Asn Pro Trp Asn Cys Pro 
            820                 825                 830


Ala Pro Met Thr Leu Cys Pro Pro Ser Ser 
        835                 840


<210>  7814
<211>  1989
<212>  DNA
<213>  Homo sapiens

<400>  7814
ggagcagagt cgtgcgtggt tgagtttaga taaaagccga gtgagcgcgc tctgttcctt     60

aagattagtt taaggtgcct tggattgctc tgaagagctt tgaccacctg atattgctta    120

catctggaac ttcttggctt ctcattcccc agatgtgcgg gtcagagaga ccatggagaa    180

aaactgcagc tcttctgtca ggaggatggg aaggtcattt gctggctttg tgagcggtct    240

caggagcacc gtggtcacca cacgttcctc gtggaggagg ttgcccagga gtaccaggag    300

aagtttcagg agtctctaaa gaagctgaag aacgaggagc aggaagctga gaagctaaca    360

gcttttatca gagagaagaa aacatcctgg aagaatcaga tggagcctga gagatgcagg    420

atccagacag agtttaatca gctgcgaaat atcctagaca gagtggagca acgggagctg    480

aaaaagctgg aacaggaaga gaagaagggg ctacgaatta tagaagaggc tgagaatgat    540

ctggtccacc agacccagtc gctgcgagag ctcatctcgg atctggagcg tcgatgtcag    600

gggtcaacaa tggagctgct gcaggatgtg agtgatgtca cagaaaggag tgagttctgg    660

accctgagga agccagaagc tctccctaca aagctgagaa gtatgttccg agccccagat    720

ctgaaaagga tgctgcgagt gtgtagagag ctgacagatg tccaaagcta ctgggttgac    780

gtgaccctga atccacacac agctaattta aatcttgtcc tggctaaaaa ccggagacaa    840

gtgaggtttg tgggagctaa agtatctgga ccttcctgtc tggaaaagca ttatgactgt    900

agtgtcctgg gctcccagca cttctcctct ggtaagcatt actgggaggt agatgtggcc    960

aagaagactg cctggatcct gggggtatgc agcaattcac tgggacctac attctctttc   1020

aaccattttg ctcaaaatca cagtgcttac tccaggtatc agcctcagag tggatactgg   1080

gtgattgggt tacagcataa ccatgaatat agggcctatg aggattcttc cccttccctg   1140

cttctctcca tgacagtgcc ccctcgccgt gttggggttt tcttagatta tgaggctggt   1200

actgtctcct tttataatgt cacaaaccat ggcttcccca tctacacttt ctctaaatat   1260

tactttccca ctactctttg tccatatttt aatccttgca actgtgtaat tcctatgacc   1320

ctgcgtcgtc caagctcttg aatattcttc tgttcccacc cacttctgat aagtaccctg   1380

aggcttatca gcatgtgatt ctcccttctg atcttctgtt tttctgtgtt ctcaaacagt   1440

tctttcgttt taaacagtta ctcagtacta ggatgcaccc ataaaatgca ataataagca   1500

aataaattac tttgtttttg tataagtatg tataggattg agctctaaaa ccaaaccatt   1560

ataatgataa tttgggtagc ttcaaactca aattgaagag agtcttcact acaatcttca   1620

ctacaacctt tggccttcct ctctacattt aagagtagca atagaacaat aaaaaaaaat   1680

acgtctttca aattaattgc agtaaaaaca aaagagtagt ggggagagaa aaacaatcca   1740

atacatattt ttctctcaga atagaaagaa aacacaaaga gaaaatatga acaatataaa   1800

gcacttaaag gaagaggatg atttcttcca gcttttccac actctcttta tgcgcaggaa   1860

caaacagctg ttgagtgagc tgctatgact ttggtagaga ggtgcaatat gttttttgaa   1920

ccagctataa aagaaattaa gaggtacatg tgagggtaga aacaaatatc aaggatgaga   1980

atggcactg                                                           1989


<210>  7815
<211>  313
<212>  PRT
<213>  Homo sapiens

<400>  7815

Met Glu Pro Glu Arg Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg 
1               5                   10                  15


Asn Ile Leu Asp Arg Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln 
            20                  25                  30


Glu Glu Lys Lys Gly Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu 
        35                  40                  45


Val His Gln Thr Gln Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg 
    50                  55                  60


Arg Cys Gln Gly Ser Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val 
65                  70                  75                  80


Thr Glu Arg Ser Glu Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro 
                85                  90                  95


Thr Lys Leu Arg Ser Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu 
            100                 105                 110


Arg Val Cys Arg Glu Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val 
        115                 120                 125


Thr Leu Asn Pro His Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn 
    130                 135                 140


Arg Arg Gln Val Arg Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys 
145                 150                 155                 160


Leu Glu Lys His Tyr Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser 
                165                 170                 175


Ser Gly Lys His Tyr Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp 
            180                 185                 190


Ile Leu Gly Val Cys Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn 
        195                 200                 205


His Phe Ala Gln Asn His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser 
    210                 215                 220


Gly Tyr Trp Val Ile Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr 
225                 230                 235                 240


Glu Asp Ser Ser Pro Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg 
                245                 250                 255


Arg Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr 
            260                 265                 270


Asn Val Thr Asn His Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr 
        275                 280                 285


Phe Pro Thr Thr Leu Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile 
    290                 295                 300


Pro Met Thr Leu Arg Arg Pro Ser Ser 
305                 310


<210>  7816
<211>  2729
<212>  DNA
<213>  Homo sapiens

<400>  7816
aaggaaagaa caggctacaa aggctttctc ctgcagcatt taccctccct ctccctggga     60

ggcttggccc aggaaagcag tcctgagccc aacttccccg cttttaatag aggagaccct    120

cagtgtgacc gactagcagc ctctttttct tccctgttcc tgaagaatca gatggagcct    180

gagagatgca ggatccagac agagtttaat cagctgcgaa atatcctaga cagagtggag    240

caacgggagc tgaaaaagct ggaacaggaa gagaagaagg ggctacgaat tatagaagag    300

gctgagaatg atctggtcca ccagacccag tcgctgcgag agctcatctc ggatctggag    360

cgtcgatgtc aggggtcaac aatggagctg ctgcaggatg tgagtgatgt cacagaaagg    420

agtgagttct ggaccctgag gaagccagaa gctctcccta caaagctgag aagtatgttc    480

cgagccccag atctgaaaag gatgctgcga gtgtgtagag agctgacaga tgtccaaagc    540

tactgggttg acgtgaccct gaatccacac acagctaatt taaatcttgt cctggctaaa    600

aaccggagac aagtgaggtt tgtgggagct aaagtatctg gaccttcctg tctggaaaag    660

cattatgact gtagtgtcct gggctcccag cacttctcct ctggtaagca ttactgggag    720

gtagatgtgg ccaagaagac tgcctggatc ctgggggtat gcagcaattc actgggacct    780

acattctctt tcaaccattt tgctcaaaat cacagtgctt actccaggta tcagcctcag    840

agtggatact gggtgattgg gttacagcat aaccatgaat atagggccta tgaggattct    900

tccccttccc tgcttctctc catgacagtg ccccctcgcc gtgttggggt tttcttagat    960

tatgaggctg gtactgtctc cttttataat gtcacaaacc atggcttccc catctacact   1020

ttctctaaat attactttcc cactactctt tgtccatatt ttaatccttg caactgtgta   1080

attcctatga ccctgcgtcg tccaagctct tgaatattct tctgttccca cccacttctg   1140

ataagtaccc tgaggcttat cagcatgtga ttctcccttc tgatcttctg tttttctgtg   1200

ttctcaattc ttttgttgtt ttttggtttt tgaatctttt ttgagatgga atctcgctct   1260

gtcgcccagg ctggagtgca ctggcgcaat ctcggctcac tgcaacctct gcctcctggg   1320

ttcaagcgaa cctcctgcct cagcatccca agtagctggg attacaggca cccaccacca   1380

tgcccaacta atttttgtat ttttatagag atagggtttc accgtgttgg ccaggctgat   1440

ctcgaactcc tgaccgcaag tgatccaccc gcctcggtct cccaaagtgc tgggattaca   1500

gatgtgagcc gccgcgccca gacagttctt tcgttttaaa cagttactca gtactaggat   1560

gcacccagtg gtgagagtaa gcatctttga ctgatgacag gtcttgaggt ggataggggg   1620

cgctttcagt attttgccat taagcatagt atttgatgca ggtttttttt gattgatgca   1680

ggggatcaaa tttaggaagt tctgatctgt taatttacta caagtttttg tataaaatga   1740

aaactcgtat tctacctatg tcttttctgt aaattattga gacaattgtg tatcattttt   1800

gttctgttaa tgtggcttag tacattgatt tacttcaatt tgttaccaca acttgctgaa   1860

atacaccatt attatttgtt gtatgcaata ctggatttat tttgataacg tattgtttag   1920

attttgttct catctatgtt aatgaaagaa attggcctgt atttttacat tcttgtaata   1980

tctttgccag gttctataaa atgcaataat aagcaaataa attactttgt ttttgtataa   2040

gtatgtatag gattgagctc taaaaccaaa ccattataat gataatttgg gtagcttcaa   2100

actcaaattg aagagagtct tcactacaat cttcactaca acctttggcc ttcctctcta   2160

catttaagag tagcaataga acaataaaaa aaaatacgtc tttcaaatta attgcagtaa   2220

aaacaaaaga gtagtgggga gagaaaaaca atccaataca tatttttctc tcagaataga   2280

aagaaaacac aaagagaaaa tatgaacaat ataaagcact taaaggaaga ggatgatttc   2340

ttccagcttt tccacactct ctttatgcgc aggaacaaac agctgttgag tgagctgcta   2400

tgactttggt agagaggtgc aatatgtttt ttgaaccagc tataaaagaa attaagaggt   2460

acatgtgagg gtagaaacaa atatcaagga tgagaatggc actggctgtc ccatatggta   2520

tccaggagcc accaatgtct gttgagtact tcatacatgc ctagtctgaa ttgagatgtg   2580

ctcaatgtat aaaatatata ccagatttca aatacctact tcaaaaaata atgtaaaata   2640

tctcactaat aacttttcct ttgtgtattg caatgataat atgttggctc tattggatta   2700

aataaagtat gttattcatt ttacctgtt                                     2729


<210>  7817
<211>  313
<212>  PRT
<213>  Homo sapiens

<400>  7817

Met Glu Pro Glu Arg Cys Arg Ile Gln Thr Glu Phe Asn Gln Leu Arg 
1               5                   10                  15


Asn Ile Leu Asp Arg Val Glu Gln Arg Glu Leu Lys Lys Leu Glu Gln 
            20                  25                  30


Glu Glu Lys Lys Gly Leu Arg Ile Ile Glu Glu Ala Glu Asn Asp Leu 
        35                  40                  45


Val His Gln Thr Gln Ser Leu Arg Glu Leu Ile Ser Asp Leu Glu Arg 
    50                  55                  60


Arg Cys Gln Gly Ser Thr Met Glu Leu Leu Gln Asp Val Ser Asp Val 
65                  70                  75                  80


Thr Glu Arg Ser Glu Phe Trp Thr Leu Arg Lys Pro Glu Ala Leu Pro 
                85                  90                  95


Thr Lys Leu Arg Ser Met Phe Arg Ala Pro Asp Leu Lys Arg Met Leu 
            100                 105                 110


Arg Val Cys Arg Glu Leu Thr Asp Val Gln Ser Tyr Trp Val Asp Val 
        115                 120                 125


Thr Leu Asn Pro His Thr Ala Asn Leu Asn Leu Val Leu Ala Lys Asn 
    130                 135                 140


Arg Arg Gln Val Arg Phe Val Gly Ala Lys Val Ser Gly Pro Ser Cys 
145                 150                 155                 160


Leu Glu Lys His Tyr Asp Cys Ser Val Leu Gly Ser Gln His Phe Ser 
                165                 170                 175


Ser Gly Lys His Tyr Trp Glu Val Asp Val Ala Lys Lys Thr Ala Trp 
            180                 185                 190


Ile Leu Gly Val Cys Ser Asn Ser Leu Gly Pro Thr Phe Ser Phe Asn 
        195                 200                 205


His Phe Ala Gln Asn His Ser Ala Tyr Ser Arg Tyr Gln Pro Gln Ser 
    210                 215                 220


Gly Tyr Trp Val Ile Gly Leu Gln His Asn His Glu Tyr Arg Ala Tyr 
225                 230                 235                 240


Glu Asp Ser Ser Pro Ser Leu Leu Leu Ser Met Thr Val Pro Pro Arg 
                245                 250                 255


Arg Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Thr Val Ser Phe Tyr 
            260                 265                 270


Asn Val Thr Asn His Gly Phe Pro Ile Tyr Thr Phe Ser Lys Tyr Tyr 
        275                 280                 285


Phe Pro Thr Thr Leu Cys Pro Tyr Phe Asn Pro Cys Asn Cys Val Ile 
    290                 295                 300


Pro Met Thr Leu Arg Arg Pro Ser Ser 
305                 310


<210>  7818
<211>  1200
<212>  DNA
<213>  Homo sapiens

<400>  7818
tgcaacctct gtctcctggg ttcaagcgat cctcctgtct cagcctcccg agtaactggg     60

attacaggcg cccaccacca tgcccggcta atttttgtat ttttgtagac agggtttcga    120

catgttggcc aggctggtct caaactcctg acctcaagtg atccacccgc ctcagcctcc    180

caaagtgctg ggattacagg tgtgagccac tgcgcccgtc ctgactcatg caacttctgc    240

ttcagccatc caggggtctt taaccagaag agagaggaga gcctcaggag ttaggaccag    300

aagaagccag ggaagcagtg caatggcttc aaaaatcttg cttaacgtac aagaggaggt    360

gacctgtccc atctgcctgg agctgttgac agaacccttg agtctagact gtggccacag    420

cctctgccga gcctgcatca ctgtgagcaa caaggaggca gtgaccagca tgggaggaaa    480

aagcagctgt cctgtgtgtg gtatcagtta ctcatttgaa catctacagg ctaatcagca    540

tctggccaac atagtggaga gactcaagga ggtcaagttg agcccagaca atgggaagaa    600

gagagatctc tgtgatcatc atggagagaa actcctactc ttctgtaagg aggataggaa    660

agtcatttgc tggctttgtg agcggtctca ggagcaccgt ggtcaccaca cagtcctcac    720

ggaggaagta ttcaaggaat gtcaggagaa actccaggca gtcctcaaga ggctgaagaa    780

ggaagaggag gaagctgaga agctggaagc tgacatcaga gaagagaaaa cttcctggaa    840

gtatcaggta caaactgaga gacaaaggat acaaacagaa tttgatcagc ttagaagcat    900

cctaaataat gaggagcaga gagagctgca aagattggaa gaagaagaaa agaagacgct    960

ggataagttt gcagaggctg aggatgagct agttcagcag aagcagttgg tgagagagct   1020

catctcagat gtggagtgtc ggagtcagtg gtcaacaatg gagctgctgc aggacatgag   1080

tggaatcatg aaatggtgcg tatgggtggc caggagtggt gcttgtgagt tataaagaag   1140

tgtttgtagc tattagagtt atttggtggt caattggaat aaaaaatctc ccagagtagt   1200


<210>  7819
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  7819

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr Gln Val 
                165                 170                 175


Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu Arg Ser 
            180                 185                 190


Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu Glu Glu 
        195                 200                 205


Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu Leu Val 
    210                 215                 220


Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu Cys Arg 
225                 230                 235                 240


Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met 
                245                 250                 255


Lys Trp Cys Val Trp Val Ala Arg Ser Gly Ala Cys Glu Leu 
            260                 265                 270


<210>  7820
<211>  967
<212>  DNA
<213>  Homo sapiens

<400>  7820
atttgttgaa tgaatcctga ccacacccac cctggctttt cttcacctct tcaaccagga     60

gccgagattt ctgttgctct gaagccatcc aggggtcttt aaccagaaga gagaggagag    120

cctcaggagt taggaccaga agaagccagg gaagcagtgc aatggcttca aaaatcttgc    180

ttaacgtaca agaggaggtg acctgtccca tctgcctgga gctgttgaca gaacccttga    240

gtctagactg tggccacagc ctctgccgag cctgcatcac tgtgagcaac aaggaggcag    300

tgaccagcat gggaggaaaa agcagctgtc ctgtgtgtgg tatcagttac tcatttgaac    360

atctacaggc taatcagcat ctggccaaca tagtggagag actcaaggag gtcaagttga    420

gcccagacaa tgggaagaag agagatctct gtgatcatca tggagagaaa ctcctactct    480

tctgtaagga ggataggaaa gtcatttgct ggctttgtga gcggtctcag gagcaccgtg    540

gtcaccacac agtcctcacg gaggaagtat tcaaggaatg tcaggagaaa ctccaggcag    600

tcctcaagag gctgaagaag gaagaggagg aagctgagaa gctggaagct gacatcagag    660

aagagaaaac ttcctggaag gcaagaggag attctgaagg ttttctgaga caggaatctt    720

gacaggacct taatccaagg aggcctcgtc ctttttattc cttgacattg catgagtcct    780

gaagccattt gattagttct cttctctgtc ctgtccctgt tgggggtgga ggctagaaag    840

tggacatgtt acaattacac atacatacct ggaactgagc acaaagatag actctatgat    900

gaggaaggct agcaaatact gtgttccatt gctcttttcc aacggggctc tactacttct    960

ggtggaa                                                              967


<210>  7821
<211>  186
<212>  PRT
<213>  Homo sapiens

<400>  7821

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Ala Arg Gly 
                165                 170                 175


Asp Ser Glu Gly Phe Leu Arg Gln Glu Ser 
            180                 185


<210>  7822
<211>  1039
<212>  DNA
<213>  Homo sapiens

<400>  7822
atttgttgaa tgaatcctga ccacacccac cctggctttt cttcacctct tcaaccagga     60

gccgagattt ctgttgctct gaagccatcc aggggtcttt aaccagaaga gagaggagag    120

cctcaggagt taggaccaga agaagccagg gaagcagtgc aatggcttca aaaatcttgc    180

ttaacgtaca agaggaggtg acctgtccca tctgcctgga gctgttgaca gaacccttga    240

gtctagactg tggccacagc ctctgccgag cctgcatcac tgtgagcaac aaggaggcag    300

tgaccagcat gggaggaaaa agcagctgtc ctgtgtgtgg tatcagttac tcatttgaac    360

atctacaggc taatcagcat ctggccaaca tagtggagag actcaaggag gtcaagttga    420

gcccagacaa tgggaagaag agagatctct gtgatcatca tggagagaaa ctcctactct    480

tctgtaagga ggataggaaa gtcatttgct ggctttgtga gcggtctcag gagcaccgtg    540

gtcaccacac agtcctcacg gaggaagtat tcaaggaatg tcaggagaaa ctccaggcag    600

tcctcaagag gctgaagaag gaagaggagg aagctgagaa gctggaagct gacatcagag    660

aagagaaaac ttcctggaag tatcaggtac aaactgagag acaaaggata caaacagaat    720

ttgatcagct tagaagcatc ctaaataatg aggagcagag agagctgcaa agattggaag    780

aagaagaaaa gaagacgctg gataagtttg cagaggctga ggatgagcta gttcagcaga    840

agcagttggt gagagagctc atctcagatg tggagtgtcg gagtcagtgg tcaacaatgg    900

agctgctgca ggacatgagt ggaatcatga aatggtgcgt atgggtggcc aggagtggtg    960

cttgtgagtt ataaagaagt gtttgtagct attagagtta tttggtggtc aattggaata   1020

aaaaatctcc cagagtagt                                                1039


<210>  7823
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  7823

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr Gln Val 
                165                 170                 175


Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu Arg Ser 
            180                 185                 190


Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu Glu Glu 
        195                 200                 205


Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu Leu Val 
    210                 215                 220


Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu Cys Arg 
225                 230                 235                 240


Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met 
                245                 250                 255


Lys Trp Cys Val Trp Val Ala Arg Ser Gly Ala Cys Glu Leu 
            260                 265                 270


<210>  7824
<211>  2314
<212>  DNA
<213>  Homo sapiens

<400>  7824
atttgttgaa tgaatcctga ccacacccac cctggctttt cttcacctct tcaaccagga     60

gccgagattt ctgttgctct gaagccatcc aggggtcttt aaccagaaga gagaggagag    120

cctcaggagt taggaccaga agaagccagg gaagcagtgc aatggcttca aaaatcttgc    180

ttaacgtaca agaggaggtg acctgtccca tctgcctgga gctgttgaca gaacccttga    240

gtctagactg tggccacagc ctctgccgag cctgcatcac tgtgagcaac aaggaggcag    300

tgaccagcat gggaggaaaa agcagctgtc ctgtgtgtgg tatcagttac tcatttgaac    360

atctacaggc taatcagcat ctggccaaca tagtggagag actcaaggag gtcaagttga    420

gcccagacaa tgggaagaag agagatctct gtgatcatca tggagagaaa ctcctactct    480

tctgtaagga ggataggaaa gtcatttgct ggctttgtga gcggtctcag gagcaccgtg    540

gtcaccacac agtcctcacg gaggaagtat tcaaggaatg tcaggagaaa ctccaggcag    600

tcctcaagag gctgaagaag gaagaggagg aagctgagaa gctggaagct gacatcagag    660

aagagaaaac ttcctggaag tatcaggtac aaactgagag acaaaggata caaacagaat    720

ttgatcagct tagaagcatc ctaaataatg aggagcagag agagctgcaa agattggaag    780

aagaagaaaa gaagacgctg gataagtttg cagaggctga ggatgagcta gttcagcaga    840

agcagttggt gagagagctc atctcagatg tggagtgtcg gagtcagtgg tcaacaatgg    900

agctgctgca ggacatgagt ggaatcatga aatggagtga gatctggagg ctgaaaaagc    960

caaaaatggt ttccaagaaa ctgaagactg tattccatgc tccagatctg agtaggatgc   1020

tgcaaatgtt tagagaactg acagctgtcc ggtgctactg ggtggatgtc acactgaatt   1080

cagtcaacct aaatttgaat cttgtccttt cagaagatca gagacaagtg atatctgtgc   1140

caatttggcc ttttcagtgt tataattatg gtgtcttggg atcccaatat ttctcctctg   1200

ggaaacatta ctgggaagtg gacgtgtcca agaaaactgc ctggatcctg ggggtatact   1260

gtagaacata ttcccgccat atgaagtatg ttgttagaag atgtgcaaat cgtcaaaatc   1320

tttacaccaa atacagacct ctatttggct actgggttat agggttacag aataaatgta   1380

agtatggtgt ctttgaagag tctttgtcct ctgatcccga ggttttgact ctctccatgg   1440

ctgtgcctcc ctgccgtgtt ggggttttcc tcgactatga agcaggcatt gtctcatttt   1500

tcaatgtcac aagccatggc tccctcattt acaagttctc taaatgttgc ttttctcagc   1560

ctgtttatcc atatttcaat ccttggaact gtccagctcc catgactcta tgcccaccaa   1620

gctcttgaat tttctcattt cttcacctac aaccctttgt cttgacttat ctcctgcaac   1680

tgactcatct gcaacattca caccattgct tccttgtggt ttcccttctt tagaactttt   1740

actcatcctt gagatgtatg gtgtatttgg cttgagttat gagagatgct tatttattca   1800

tttactcttt ttcatatttt cagagaaagt tacctaatcc ctcctaaaga cacagcagta   1860

tgggtataac atccttgcct tcccatttat ccatgtttca ctttatcact gatatgaaga   1920

ggcccaaagc ctgttagcca ccatccatgc tacctaggta gtccatagga accaccccca   1980

tgaccaccac caacatcaac taaaggttct tggagggtat gtcagtgtgt tgctcaggat   2040

accccaggta catcaaggaa tcaaggagag gaaaatatga gcaatatgtg tattcagagt   2100

gaagatttta tgtccagagt atttgagctc aaaccttgcc tgttgttttc taatcatgat   2160

gaatactttc tcagtttctt tttcctgaaa tataaattgg gatttaagac tgtacctaac   2220

tattaagatc actgtgtaaa actaagtgtc tctaaatgta atgcatcgat ttagtgtctg   2280

gaacataata aatatttgct ctcatgattg ctaa                               2314


<210>  7825
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7825

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr Gln Val 
                165                 170                 175


Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu Arg Ser 
            180                 185                 190


Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu Glu Glu 
        195                 200                 205


Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu Leu Val 
    210                 215                 220


Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu Cys Arg 
225                 230                 235                 240


Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met 
                245                 250                 255


Lys Trp Ser Glu Ile Trp Arg Leu Lys Lys Pro Lys Met Val Ser Lys 
            260                 265                 270


Lys Leu Lys Thr Val Phe His Ala Pro Asp Leu Ser Arg Met Leu Gln 
        275                 280                 285


Met Phe Arg Glu Leu Thr Ala Val Arg Cys Tyr Trp Val Asp Val Thr 
    290                 295                 300


Leu Asn Ser Val Asn Leu Asn Leu Asn Leu Val Leu Ser Glu Asp Gln 
305                 310                 315                 320


Arg Gln Val Ile Ser Val Pro Ile Trp Pro Phe Gln Cys Tyr Asn Tyr 
                325                 330                 335


Gly Val Leu Gly Ser Gln Tyr Phe Ser Ser Gly Lys His Tyr Trp Glu 
            340                 345                 350


Val Asp Val Ser Lys Lys Thr Ala Trp Ile Leu Gly Val Tyr Cys Arg 
        355                 360                 365


Thr Tyr Ser Arg His Met Lys Tyr Val Val Arg Arg Cys Ala Asn Arg 
    370                 375                 380


Gln Asn Leu Tyr Thr Lys Tyr Arg Pro Leu Phe Gly Tyr Trp Val Ile 
385                 390                 395                 400


Gly Leu Gln Asn Lys Cys Lys Tyr Gly Val Phe Glu Glu Ser Leu Ser 
                405                 410                 415


Ser Asp Pro Glu Val Leu Thr Leu Ser Met Ala Val Pro Pro Cys Arg 
            420                 425                 430


Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Ile Val Ser Phe Phe Asn 
        435                 440                 445


Val Thr Ser His Gly Ser Leu Ile Tyr Lys Phe Ser Lys Cys Cys Phe 
    450                 455                 460


Ser Gln Pro Val Tyr Pro Tyr Phe Asn Pro Trp Asn Cys Pro Ala Pro 
465                 470                 475                 480


Met Thr Leu Cys Pro Pro Ser Ser 
                485


<210>  7826
<211>  2219
<212>  DNA
<213>  Homo sapiens

<400>  7826
accctggctt ttcttcacct cttcaaccag gagccgagat ttctgttgct ctgaagccat     60

ccaggggtct ttaaccagaa gagagaggag agcctcagga gttaggacca gaagaagcca    120

gggaagcagt gcaatggctt caaaaatctt gcttaacgta caagaggagg tgacctgtcc    180

catctgcctg gagctgttga cagaaccctt gagtctagac tgtggccaca gcctctgccg    240

agcctgcatc actgtgagca acaaggaggc agtgaccagc atgggaggaa aaagcagctg    300

tcctgtgtgt ggtatcagtt actcatttga acatctacag gctaatcagc atctggccaa    360

catagtggag agactcaagg aggtcaagtt gagcccagac aatgggaaga agagagatct    420

ctgtgatcat catggagaga aactcctact cttctgtaag gaggatagga aatattcaag    480

gaatgtcagg agaaactcca ggcagtcctc aagaggctga agaaggaaga ggaggaagct    540

gagaagctgg aagctgacat cagagaagag aaaacttcct ggaagtatca ggtacaaact    600

gagagacaaa ggatacaaac agaatttgat cagcttagaa gcatcctaaa taatgaggag    660

cagagagagc tgcaaagatt ggaagaagaa gaaaagaaga cgctggataa gtttgcagag    720

gctgaggatg agctagttca gcagaagcag ttggtgagag agctcatctc agatgtggag    780

tgtcggagtc agtggtcaac aatggagctg ctgcaggaca tgagtggaat catgaaatgg    840

agtgagatct ggaggctgaa aaagccaaaa atggtttcca agaaactgaa gactgtattc    900

catgctccag atctgagtag gatgctgcaa atgtttagag aactgacagc tgtccggtgc    960

tactgggtgg atgtcacact gaattcagtc aacctaaatt tgaatcttgt cctttcagaa   1020

gatcagagac aagtgatatc tgtgccaatt tggccttttc agtgttataa ttatggtgtc   1080

ttgggatccc aatatttctc ctctgggaaa cattactggg aagtggacgt gtccaagaaa   1140

actgcctgga tcctgggggt atactgtaga acatattccc gccatatgaa gtatgttgtt   1200

agaagatgtg caaatcgtca aaatctttac accaaataca gacctctatt tggctactgg   1260

gttatagggt tacagaataa atgtaagtat ggtgtctttg aagagtcttt gtcctctgat   1320

cccgaggttt tgactctctc catggctgtg cctccctgcc gtgttggggt tttcctcgac   1380

tatgaagcag gcattgtctc atttttcaat gtcacaagcc atggctccct catttacaag   1440

ttctctaaat gttgcttttc tcagcctgtt tatccatatt tcaatccttg gaactgtcca   1500

gctcccatga ctctatgccc accaagctct tgaattttct catttcttca cctacaaccc   1560

tttgtcttga cttatctcct gcaactgact catctgcaac attcacacca ttgcttcctt   1620

gtggtttccc ttctttagaa cttttactca tccttgagat gtatggtgta tttggcttga   1680

gttatgagag atgcttattt attcatttac tctttttcat attttcagag aaagttacct   1740

aatccctcct aaagacacag cagtatgggt ataacatcct tgccttccca tttatccatg   1800

tttcacttta tcactgatat gaagaggccc aaagcctgtt agccaccatc catgctacct   1860

aggtagtcca taggaaccac ccccatgacc accaccaaca tcaactaaag gttcttggag   1920

ggtatgtcag tgtgttgctc aggatacccc aggtacatca aggaatcaag gagaggaaaa   1980

tatgagcaat atgtgtattc agagtgaaga ttttatgtcc agagtatttg agctcaaacc   2040

ttgcctgttg ttttctaatc atgatgaata ctttctcagt ttctttttcc tgaaatataa   2100

attgggattt aagactgtac ctaactatta agatcactgt gtaaaactaa gtgtctctaa   2160

atgtaatgca tcgatttagt gtctggaaca taataaatat ttgctctcat gattgctaa    2219


<210>  7827
<211>  243
<212>  PRT
<213>  Homo sapiens

<400>  7827

Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met Lys Trp Ser Glu Ile 
1               5                   10                  15


Trp Arg Leu Lys Lys Pro Lys Met Val Ser Lys Lys Leu Lys Thr Val 
            20                  25                  30


Phe His Ala Pro Asp Leu Ser Arg Met Leu Gln Met Phe Arg Glu Leu 
        35                  40                  45


Thr Ala Val Arg Cys Tyr Trp Val Asp Val Thr Leu Asn Ser Val Asn 
    50                  55                  60


Leu Asn Leu Asn Leu Val Leu Ser Glu Asp Gln Arg Gln Val Ile Ser 
65                  70                  75                  80


Val Pro Ile Trp Pro Phe Gln Cys Tyr Asn Tyr Gly Val Leu Gly Ser 
                85                  90                  95


Gln Tyr Phe Ser Ser Gly Lys His Tyr Trp Glu Val Asp Val Ser Lys 
            100                 105                 110


Lys Thr Ala Trp Ile Leu Gly Val Tyr Cys Arg Thr Tyr Ser Arg His 
        115                 120                 125


Met Lys Tyr Val Val Arg Arg Cys Ala Asn Arg Gln Asn Leu Tyr Thr 
    130                 135                 140


Lys Tyr Arg Pro Leu Phe Gly Tyr Trp Val Ile Gly Leu Gln Asn Lys 
145                 150                 155                 160


Cys Lys Tyr Gly Val Phe Glu Glu Ser Leu Ser Ser Asp Pro Glu Val 
                165                 170                 175


Leu Thr Leu Ser Met Ala Val Pro Pro Cys Arg Val Gly Val Phe Leu 
            180                 185                 190


Asp Tyr Glu Ala Gly Ile Val Ser Phe Phe Asn Val Thr Ser His Gly 
        195                 200                 205


Ser Leu Ile Tyr Lys Phe Ser Lys Cys Cys Phe Ser Gln Pro Val Tyr 
    210                 215                 220


Pro Tyr Phe Asn Pro Trp Asn Cys Pro Ala Pro Met Thr Leu Cys Pro 
225                 230                 235                 240


Pro Ser Ser 



<210>  7828
<211>  1985
<212>  DNA
<213>  Homo sapiens

<400>  7828
cttcacctct tcaaccagga gccgagattt ctgttgctct gaagccatcc aggggtcttt     60

aaccagaaga gagaggagag cctcaggagt taggaccaga agaagccagg gaagcagtgc    120

aatggcttca aaaatcttgc ttaacgtaca agaggaggtg acctgtccca tctgcctgga    180

gctgttgaca gaacccttga gtctagactg tggccacagc ctctgccgag cctgcatcac    240

tgtgagcaac aaggaggcag tgaccagcat gggaggaaaa agcagctgtc ctgtgtgtgg    300

tatcagttac tcatttgaac atctacaggc taatcagcat ctggccaaca tagtggagag    360

actcaaggag gtcaagttga gcccagacaa tgggaagaag agagatctct gtgatcatca    420

tggagagaaa ctcctactct tctgtaagga ggataggaaa tattcaagga atgtcaggag    480

aaactccagg cagtcctcaa gaggctgaag aaggaagagg aggaagctga gaagctggaa    540

gctgacatca gagaagagaa aacttcctgg aagtatcagg tacaaactga gagacaaagg    600

atacaaacag aatttgatca gcttagaagc atcctaaata atgaggagca gagagagctg    660

caaagattgg aagaagaaga aaagaagacg ctggataagt ttgcagaggc tgaggatgag    720

ctagttcagc agaagcagtt ggtgagagag ctcatctcag atgtggagtg tcggagtcag    780

tggtcaacaa tggagctgct gcaggacatg agtggaatca tgaaatggag tgagatctgg    840

aggctgaaaa agccaaaaat ggtttccaag aaactgaaga ctgtattcca tgctccagat    900

ctgagtagga tgctgcaaat gtttagagaa ctgacagctg tccggtgcta ctgggtggat    960

gtcacactga attcagtcaa cctaaatttg aatcttgtcc tttcagaaga tcagagacaa   1020

gtgatatctg tgccaatttg gccttttcag tgttataatt atggtgtctt gggatcccaa   1080

tatttctcct ctgggaaaca ttactgggaa gtggacgtgt ccaagaaaac tgcctggatc   1140

ctgggggtat actgtagaac atattcccgc catatgaagt atgttgttag aagatgtgca   1200

aatcgtcaaa atctttacac caaatacaga cctctatttg gctactgggt tatagggtta   1260

cagaataaat gtaagtatgg tgtctttgaa gagtctttgt cctctgatcc cgaggttttg   1320

actctctcca tggctgtgcc tccctgccgt gttggggttt tcctcgacta tgaagcaggc   1380

attgtctcat ttttcaatgt cacaagccat ggctccctca tttacaagtt ctctaaatgt   1440

tgcttttctc agcctgttta tccatatttc aatccttgga actgtccagc tcccatgact   1500

ctatgcccac caagctcttg aattttctca tttcttcacc tacaaccctt tgtcttgact   1560

tatctcctgc aactgactca tctgcaacat tcacaccatt gcttccttgt ggtttccctt   1620

ctttagaact tttactcatc cttgagatgt atggtgtatt tggcttgagt tatgagagat   1680

gcttatttat tcatttactc tttttcatat tttcagagaa agttacctaa tccctcctaa   1740

agacacagca gtatgggtat aacatccttg ccttcccatt tatccatgtt tcactttatc   1800

actgatatga agaggcccaa agcctgttag ccaccatcca tgctacctag gtagtccata   1860

ggaaccaccc ccatgaccac caccaacatc aactaaaggt tcttggaggg tatgtcagtg   1920

tgttgctcag gataccccag gtacatcaag gaatcaagga gaggaaaata tgagcaatat   1980

gtgta                                                               1985


<210>  7829
<211>  243
<212>  PRT
<213>  Homo sapiens

<400>  7829

Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met Lys Trp Ser Glu Ile 
1               5                   10                  15


Trp Arg Leu Lys Lys Pro Lys Met Val Ser Lys Lys Leu Lys Thr Val 
            20                  25                  30


Phe His Ala Pro Asp Leu Ser Arg Met Leu Gln Met Phe Arg Glu Leu 
        35                  40                  45


Thr Ala Val Arg Cys Tyr Trp Val Asp Val Thr Leu Asn Ser Val Asn 
    50                  55                  60


Leu Asn Leu Asn Leu Val Leu Ser Glu Asp Gln Arg Gln Val Ile Ser 
65                  70                  75                  80


Val Pro Ile Trp Pro Phe Gln Cys Tyr Asn Tyr Gly Val Leu Gly Ser 
                85                  90                  95


Gln Tyr Phe Ser Ser Gly Lys His Tyr Trp Glu Val Asp Val Ser Lys 
            100                 105                 110


Lys Thr Ala Trp Ile Leu Gly Val Tyr Cys Arg Thr Tyr Ser Arg His 
        115                 120                 125


Met Lys Tyr Val Val Arg Arg Cys Ala Asn Arg Gln Asn Leu Tyr Thr 
    130                 135                 140


Lys Tyr Arg Pro Leu Phe Gly Tyr Trp Val Ile Gly Leu Gln Asn Lys 
145                 150                 155                 160


Cys Lys Tyr Gly Val Phe Glu Glu Ser Leu Ser Ser Asp Pro Glu Val 
                165                 170                 175


Leu Thr Leu Ser Met Ala Val Pro Pro Cys Arg Val Gly Val Phe Leu 
            180                 185                 190


Asp Tyr Glu Ala Gly Ile Val Ser Phe Phe Asn Val Thr Ser His Gly 
        195                 200                 205


Ser Leu Ile Tyr Lys Phe Ser Lys Cys Cys Phe Ser Gln Pro Val Tyr 
    210                 215                 220


Pro Tyr Phe Asn Pro Trp Asn Cys Pro Ala Pro Met Thr Leu Cys Pro 
225                 230                 235                 240


Pro Ser Ser 



<210>  7830
<211>  1044
<212>  DNA
<213>  Homo sapiens

<400>  7830
ctcttcaacc aggagccgag atttctgttg ctctgaagga gaacagtgtg gaagattaag     60

atgggagtgt gcctggagag gcataaaagc catccagggg tctttaacca gaagagagag    120

gagagcctca ggagttagga ccagaagaag ccagggaagc agtgcaatgg cttcaaaaat    180

cttgcttaac gtacaagagg aggtgacctg tcccatctgc ctggagctgt tgacagaacc    240

cttgagtcta gactgtggcc acagcctctg ccgagcctgc atcactgtga gcaacaagga    300

ggcagtgacc agcatgggag gaaaaagcag ctgtcctgtg tgtggtatca gttactcatt    360

tgaacatcta caggctaatc agcatctggc caacatagtg gagagactca aggaggtcaa    420

gttgagccca gacaatggga agaagagaga tctctgtgat catcatggag agaaactcct    480

actcttctgt aaggaggata ggaaagtcat ttgctggctt tgtgagcggt ctcaggagca    540

ccgtggtcac cacacagtcc tcacggagga agtattcaag gaatgtcagg agaaactcca    600

ggcagtcctc aagaggctga agaaggaaga ggaggaagct gagaagctgg aagctgacat    660

cagagaagag aaaacttcct ggaagtatca ggtacaaact gagagacaaa ggatacaaac    720

agaatttgat cagcttagaa gcatcctaaa taatgaggag cagagagagc tgcaaagatt    780

ggaagaagaa gaaaagaaga cgctggataa gtttgcagag gctgaggatg agctagttca    840

gcagaagcag ttggtgagag agctcatctc agatgtggag tgtcggagtc agtggtcaac    900

aatggagctg ctgcaggaca tgagtggaat catgaaatgg tgcgtatggg tggccaggag    960

tggtgcttgt gagttataaa gaagtgtttg tagctattag agttatttgg tggtcaattg   1020

gaataaaaaa tctcccagag tagt                                          1044


<210>  7831
<211>  270
<212>  PRT
<213>  Homo sapiens

<400>  7831

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr Gln Val 
                165                 170                 175


Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu Arg Ser 
            180                 185                 190


Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu Glu Glu 
        195                 200                 205


Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu Leu Val 
    210                 215                 220


Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu Cys Arg 
225                 230                 235                 240


Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met 
                245                 250                 255


Lys Trp Cys Val Trp Val Ala Arg Ser Gly Ala Cys Glu Leu 
            260                 265                 270


<210>  7832
<211>  2305
<212>  DNA
<213>  Homo sapiens

<400>  7832
cctgcctcgg cctcccaaag tgctgagatt acaggggtga gccaccgcgc ccggcctcac     60

tttcaatctt ctcagccatc caggggtctt taaccagaag agagaggaga gcctcaggag    120

ttaggaccag aagaagccag ggaagcagtg caatggcttc aaaaatcttg cttaacgtac    180

aagaggaggt gacctgtccc atctgcctgg agctgttgac agaacccttg agtctagact    240

gtggccacag cctctgccga gcctgcatca ctgtgagcaa caaggaggca gtgaccagca    300

tgggaggaaa aagcagctgt cctgtgtgtg gtatcagtta ctcatttgaa catctacagg    360

ctaatcagca tctggccaac atagtggaga gactcaagga ggtcaagttg agcccagaca    420

atgggaagaa gagagatctc tgtgatcatc atggagagaa actcctactc ttctgtaagg    480

aggataggaa agtcatttgc tggctttgtg agcggtctca ggagcaccgt ggtcaccaca    540

cagtcctcac ggaggaagta ttcaaggaat gtcaggagaa actccaggca gtcctcaaga    600

ggctgaagaa ggaagaggag gaagctgaga agctggaagc tgacatcaga gaagagaaaa    660

cttcctggaa gtatcaggta caaactgaga gacaaaggat acaaacagaa tttgatcagc    720

ttagaagcat cctaaataat gaggagcaga gagagctgca aagattggaa gaagaagaaa    780

agaagacgct ggataagttt gcagaggctg aggatgagct agttcagcag aagcagttgg    840

tgagagagct catctcagat gtggagtgtc ggagtcagtg gtcaacaatg gagctgctgc    900

aggacatgag tggaatcatg aaatggagtg agatctggag gctgaaaaag ccaaaaatgg    960

tttccaagaa actgaagact gtattccatg ctccagatct gagtaggatg ctgcaaatgt   1020

ttagagaact gacagctgtc cggtgctact gggtggatgt cacactgaat tcagtcaacc   1080

taaatttgaa tcttgtcctt tcagaagatc agagacaagt gatatctgtg ccaatttggc   1140

cttttcagtg ttataattat ggtgtcttgg gatcccaata tttctcctct gggaaacatt   1200

actgggaagt ggacgtgtcc aagaaaactg cctggatcct gggggtatac tgtagaacat   1260

attcccgcca tatgaagtat gttgttagaa gatgtgcaaa tcgtcaaaat ctttacacca   1320

aatacagacc tctatttggc tactgggtta tagggttaca gaataaatgt aagtatggtg   1380

tctttgaaga gtctttgtcc tctgatcccg aggttttgac tctctccatg gctgtgcctc   1440

cctgccgtgt tggggttttc ctcgactatg aagcaggcat tgtctcattt ttcaatgtca   1500

caagccatgg ctccctcatt tacaagttct ctaaatgttg cttttctcag cctgtttatc   1560

catatttcaa tccttggaac tgtccagctc ccatgactct atgcccacca agctcttgaa   1620

ttttctcatt tcttcaccta caaccctttg tcttgactta tctcctgcaa ctgactcatc   1680

tgcaacattc acaccattgc ttccttgtgg tttcccttct ttagaacttt tactcatcct   1740

tgagatgtat ggtgtatttg gcttgagtta tgagagatgc ttatttattc atttactctt   1800

tttcatattt tcagagaaag ttacctaatc cctcctaaag acacagcagt atgggtataa   1860

catccttgcc ttcccattta tccatgtttc actttatcac tgatatgaag aggcccaaag   1920

cctgttagcc accatccatg ctacctaggt agtccatagg aaccaccccc atgaccacca   1980

ccaacatcaa ctaaaggttc ttggagggta tgtcagtgtg ttgctcagga taccccaggt   2040

acatcaagga atcaaggaga ggaaaatatg agcaatatgt gtattcagag tgaagatttt   2100

atgtccagag tatttgagct caaaccttgc ctgttgtttt ctaatcatga tgaatacttt   2160

ctcagtttct ttttcctgaa atataaattg ggatttaaga ctgtacctaa ctattaagat   2220

cactgtgtaa aactaagtgt ctctaaatgt aatgcatcga tttagtgtct ggaacataat   2280

aaatatttgc tctcatgatt gctaa                                         2305


<210>  7833
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  7833

Met Ala Ser Lys Ile Leu Leu Asn Val Gln Glu Glu Val Thr Cys Pro 
1               5                   10                  15


Ile Cys Leu Glu Leu Leu Thr Glu Pro Leu Ser Leu Asp Cys Gly His 
            20                  25                  30


Ser Leu Cys Arg Ala Cys Ile Thr Val Ser Asn Lys Glu Ala Val Thr 
        35                  40                  45


Ser Met Gly Gly Lys Ser Ser Cys Pro Val Cys Gly Ile Ser Tyr Ser 
    50                  55                  60


Phe Glu His Leu Gln Ala Asn Gln His Leu Ala Asn Ile Val Glu Arg 
65                  70                  75                  80


Leu Lys Glu Val Lys Leu Ser Pro Asp Asn Gly Lys Lys Arg Asp Leu 
                85                  90                  95


Cys Asp His His Gly Glu Lys Leu Leu Leu Phe Cys Lys Glu Asp Arg 
            100                 105                 110


Lys Val Ile Cys Trp Leu Cys Glu Arg Ser Gln Glu His Arg Gly His 
        115                 120                 125


His Thr Val Leu Thr Glu Glu Val Phe Lys Glu Cys Gln Glu Lys Leu 
    130                 135                 140


Gln Ala Val Leu Lys Arg Leu Lys Lys Glu Glu Glu Glu Ala Glu Lys 
145                 150                 155                 160


Leu Glu Ala Asp Ile Arg Glu Glu Lys Thr Ser Trp Lys Tyr Gln Val 
                165                 170                 175


Gln Thr Glu Arg Gln Arg Ile Gln Thr Glu Phe Asp Gln Leu Arg Ser 
            180                 185                 190


Ile Leu Asn Asn Glu Glu Gln Arg Glu Leu Gln Arg Leu Glu Glu Glu 
        195                 200                 205


Glu Lys Lys Thr Leu Asp Lys Phe Ala Glu Ala Glu Asp Glu Leu Val 
    210                 215                 220


Gln Gln Lys Gln Leu Val Arg Glu Leu Ile Ser Asp Val Glu Cys Arg 
225                 230                 235                 240


Ser Gln Trp Ser Thr Met Glu Leu Leu Gln Asp Met Ser Gly Ile Met 
                245                 250                 255


Lys Trp Ser Glu Ile Trp Arg Leu Lys Lys Pro Lys Met Val Ser Lys 
            260                 265                 270


Lys Leu Lys Thr Val Phe His Ala Pro Asp Leu Ser Arg Met Leu Gln 
        275                 280                 285


Met Phe Arg Glu Leu Thr Ala Val Arg Cys Tyr Trp Val Asp Val Thr 
    290                 295                 300


Leu Asn Ser Val Asn Leu Asn Leu Asn Leu Val Leu Ser Glu Asp Gln 
305                 310                 315                 320


Arg Gln Val Ile Ser Val Pro Ile Trp Pro Phe Gln Cys Tyr Asn Tyr 
                325                 330                 335


Gly Val Leu Gly Ser Gln Tyr Phe Ser Ser Gly Lys His Tyr Trp Glu 
            340                 345                 350


Val Asp Val Ser Lys Lys Thr Ala Trp Ile Leu Gly Val Tyr Cys Arg 
        355                 360                 365


Thr Tyr Ser Arg His Met Lys Tyr Val Val Arg Arg Cys Ala Asn Arg 
    370                 375                 380


Gln Asn Leu Tyr Thr Lys Tyr Arg Pro Leu Phe Gly Tyr Trp Val Ile 
385                 390                 395                 400


Gly Leu Gln Asn Lys Cys Lys Tyr Gly Val Phe Glu Glu Ser Leu Ser 
                405                 410                 415


Ser Asp Pro Glu Val Leu Thr Leu Ser Met Ala Val Pro Pro Cys Arg 
            420                 425                 430


Val Gly Val Phe Leu Asp Tyr Glu Ala Gly Ile Val Ser Phe Phe Asn 
        435                 440                 445


Val Thr Ser His Gly Ser Leu Ile Tyr Lys Phe Ser Lys Cys Cys Phe 
    450                 455                 460


Ser Gln Pro Val Tyr Pro Tyr Phe Asn Pro Trp Asn Cys Pro Ala Pro 
465                 470                 475                 480


Met Thr Leu Cys Pro Pro Ser Ser 
                485


<210>  7834
<211>  979
<212>  DNA
<213>  Homo sapiens

<400>  7834
gggtccggct ctcccttctc cccctcctca ggctcaggga gaagggttca agtgcatcag     60

tgatgtgaag gagatgaaac cagtgatgtg ggagggatgg acacaggatg agagatgtgg    120

gggtcaaaaa atttttttca tccctaggag tgagatctgg aggctgaaaa agccaaaaat    180

ggtttccaag aaactgaaga ctgtattcca tgctccagat ctgagtagga tgctgcaaat    240

gtttagaggt gaggagaagc agacaaagac tgtggatgtg ggattgttgt ggtgtcaggt    300

aataaactgt ctaggtggga taacttaaaa ttgaggacag aagagaggag ggaggtcaga    360

gaataaggaa tattctgtgg tgaagaggat gcatttatat gtaaggaaaa atggctaggt    420

ctctggttta tctttttaat tcactagctc acagcttcat ggtattccct tcccctgtcc    480

ctactctaaa gaatatatag gtatcagtgc ttactccttt gtttctaatc agcatcactg    540

aatcttttat tatttcagaa ctgacagctg tccggtgcta ctggggtaag aaaaagttag    600

tctttaaata actgttttcc aattaccttt cagaagttta tggtttcaat gatatcttct    660

gatcttagcc tcatgcattc tcagcacctc ccaaaacatt tgctaaatac atttctccag    720

tgttttaccc ctccaattca tcagtgcaag tttttcagtc acttcccaag ttcgttcatc    780

accatgtcac tagataaacc tactccatat ctgtcactaa tcatgatgaa tactttctca    840

gtttcttttt cctgaaatat aaattgggat ttaagactgt acctaactat taagatcact    900

gtgtaaaact aagtgtctct aaatgtaatg catcgattta gtgtctggaa cataataaat    960

atttgctctc atgattgct                                                 979


<210>  7835
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  7835

Met Val Ser Met Ile Ser Ser Asp Leu Ser Leu Met His Ser Gln His 
1               5                   10                  15


Leu Pro Lys His Leu Leu Asn Thr Phe Leu Gln Cys Phe Thr Pro Pro 
            20                  25                  30


Ile His Gln Cys Lys Phe Phe Ser His Phe Pro Ser Ser Phe Ile Thr 
        35                  40                  45


Met Ser Leu Asp Lys Pro Thr Pro Tyr Leu Ser Leu Ile Met Met Asn 
    50                  55                  60


Thr Phe Ser Val Ser Phe Ser 
65                  70


<210>  7836
<211>  1264
<212>  DNA
<213>  Homo sapiens

<400>  7836
cttgtccttt cagaagatca gagacaagtg atatctgtgc caatttggcc ttttcagtgt     60

tataattatg gtgtcttggg atcccaatat ttctcccagt aatgtttccc tgatgtgata    120

ctttgagagc ccaggatgcc agtacaataa ttgaaattca caaatgtctg gtatcttgtc    180

cctcgtgccc catatattat ctgtggtttc ggagagctca cttgtctctt atcttcagaa    240

atgacagcac atgaaatgtt gtttggagcc actgtcacat caactgtaga aaaattaaca    300

ggtcagctaa gggatataat gtaactttat ttgtgatatg agagaaatct tgataaagac    360

ttgagagaaa actgggagga accttgttta gaagttataa ggaggggtaa gttatgtgtg    420

tcttggaagg agaatcataa atcttaaaac atgagcctaa tagagaacat aaaattctaa    480

aagataaaga taataataat gataagccgc agggtggctt atgataatgt gacttctcct    540

taccccagta gcgtcggaca tctgtcagct ctgaaatgat aaaaatgcac aatattgaat    600

acaaacaaag gagtcagcac tgaaattcat tttctctcca gattagggaa agagtaggta    660

tgccctatgg tagggcagta aattgctgaa tgatgagatg aaacagccac ctagccattt    720

cccattaaat ataatcccat cagcagcaga caatatctat cctcccctat cccctctatc    780

catatttgga aactgcaccc tcttccctat ttagcaccct aacaccactt gaattccata    840

accctgttgt tgatctagct ctcctcacct ctaaacactt ctagcattcc tttcagatca    900

ggagctcgaa acactctcct ttgatttttt ggaaaagttt ctggcttctt caaggtcacg    960

ttctccgtcc taagaattaa aaaaaaaaaa aaaaacttcc aaacctttga ccttgtgtcc   1020

gtggaacacc cctgacttcc tatcatttca acccattgag gcacttgaac tctcttcttg   1080

gggatcctga gaagggagag tgcaaactct tgaccctgga ggcaaacaaa atgttctcat   1140

gtttgccttc ccacttactt tctgtgagaa cgtgggaaga tcttaacctc tcagaagcac   1200

agtttcttcc ttctaaaatg aaataattaa cctctccctg tctacattct taaactcata   1260

ggac                                                                1264


<210>  7837
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  7837

Met Lys Gln Pro Pro Ser His Phe Pro Leu Asn Ile Ile Pro Ser Ala 
1               5                   10                  15


Ala Asp Asn Ile Tyr Pro Pro Leu Ser Pro Leu Ser Ile Phe Gly Asn 
            20                  25                  30


Cys Thr Leu Phe Pro Ile 
        35


<210>  7838
<211>  1482
<212>  DNA
<213>  Homo sapiens

<400>  7838
cggctagtat cgcgagatca ggaaggtggc cgagtgtgtc gccgcggcca tcaggcactt     60

ctccttcctg cccttgtatg aagaaggatg tgtttgcttc cccttgtgcc atgattgtaa    120

atttcctgag gcctcctcag ccctgcagaa ctggggttat agccatgtga ctgatcttcg    180

tccaagaata tgtaaagaaa aagtgttgag ttggctttta gggctagagc aatgtatctt    240

aggctcactt aaggaagctg tagagatgag cccaaggagg gaaaccagaa gagcccccca    300

ggctcaccag ttgtttgttg gctccctaca aacatgtcat tcaagtggct aatcttacaa    360

cagcacaaat tcatctaacc agaaagagaa gaggaggctc caaaggcact tgactactga    420

gcatcaccct ggacgtgtac aagtctgcgt ccttattgtt ttcttcattg ggccgaactt    480

tctggtcctc atccaacagc tcttctatca cgtgttcgaa agtgtcagcc aatgatgtca    540

agcctcttga acctgccttg ggcccattca cgctctccag agtcccatgg gtccgcacac    600

ctggagatac tctattatag caaagaagaa agataatttc attgagccat cctgttttac    660

aggaaattct gcaagtggca acgtgggtcc attccgtgtg tgtcactaga gctggcgcaa    720

gcccatggcc atggtgaggc agcgtttcca ctggaactaa tctgatacct gcaccagctc    780

ttgcaactgt gcagtgttcc cactgcaaac tacggatggg gtaaaagact gctcacctcc    840

tatttctcat ctaatctcac acactctgtt tgatgaggct atggagaaac aggtcttctc    900

atacactaaa ggtgggagta caaacaattc aagccctgtg caggacaatt aggcaatacc    960

tatcaaaatt atacatgatt tttcctgctg acccagcaat tccacttctg ggaataattg   1020

acagatatag gtgcatatgt acaaaatgat ggaaagctct ctggtatata ttagtaagtg   1080

ataaaacaag gtgtaaaata gtgtatatat ggctactacc ttttgtttta aaaatggggg   1140

aaaatggtgg agcttgcggt gagccgagat cgtgccactg cactccagcc tgggcgacag   1200

agcgagactc cgtctcaaaa aaaaaacagg gtggggtggg ggggaaataa tagtacatac   1260

tcatatttac ctgtatctat ataaaacaca ctatcaagga ttcacaagaa actaatacaa   1320

atgatcacct tatagatggt atgtattggg ggatactgag gtgagcaggg tataagtggg   1380

gcaagacttt tcagtgtaaa cttcttttaa attttatttt gatttttgaa taatgtaaat   1440

taactgtcaa ataattaaat taaaaataac caatttatta ac                      1482


<210>  7839
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  7839

Met Gly Pro His Thr Trp Arg Tyr Ser Ile Ile Ala Lys Lys Lys Asp 
1               5                   10                  15


Asn Phe Ile Glu Pro Ser Cys Phe Thr Gly Asn Ser Ala Ser Gly Asn 
            20                  25                  30


Val Gly Pro Phe Arg Val Cys His 
        35                  40


<210>  7840
<211>  2326
<212>  DNA
<213>  Homo sapiens

<400>  7840
cggctagtat cgcgagatca ggaaggtggc cgagtgtgtc gccgcggcca tcaggcactt     60

ctccttcctg cccttgtatg aagaaggatg tgtttgcttc cccttgtgcc atgattgtaa    120

atttcctgag gcctcctcag ccctgcagaa ctggggttat agccatgtga ctgatcttcg    180

tccaagaata tgtaaagaaa aagtgttgag ttggctttta gggctagagc aatgtatctt    240

aggctcactt aaggaagctg tagagatgag cccaaggagg gaaaccagaa gagcccccca    300

ggctcaccag ttgtttgttg gctccctaca aacatgtcat tcaagtggct aatcttacaa    360

cagcacaaat tcatctaacc agaaagagaa gaggaggctc caaaggcact tgactactga    420

gcatcaccct ggacgtgtac aagtctgcgt ccttattgtt ttcttcattg ggccgaactt    480

tctggtcctc atccaacagc tcttctatca cgtgttcgaa agtgtcagcc aatgatgtca    540

agcctcttga acctgccttg ggcccattca cgctctccag agtcccatgg gtccgcacac    600

ctggagatac tctattatag caaagaagaa agataatttc attgagccat cctgttttac    660

agtattgaat tattaccaca aggtaccaac catatatgca tacttaatag ggtattttgt    720

caaaactatg catgaaggtc atttgtttga gatgtcagaa cattttcccg tgagaagatc    780

tcattgggca ttgaaacaga accacatgct cttcagacca gcaaccgcga ctaccaaata    840

ctcctctgtc aactctactt gagtaagaac gctttcaatt aaggcctaag tgtcaacatg    900

cctttaaaaa aaatcgtggt gacacaaaat ctttcttttt agcacccaac agaatccctt    960

caaagcctcg tggtctgaca ccctatgcta cgtgacttgt gacccatcca tttgtcatgt   1020

tcttcgggaa tgtggctaag gggctaagat gtgacttgaa aagaaaggta gaacaagatc   1080

atctcaaatt tattatcaag gaatagttca gaaaacgact tcagaccaca gagacagcag   1140

aacagatggt ccggcatgga tagagcatca gacactcaca gactgtgcca acaagagcca   1200

tcgagtcaaa acagccaaag gaaggagggt catggaatgg gttctctcac accaaactga   1260

tgcccagagg ccctcagcat gaataacaaa ggcaaccaga cccacaagcc atactgagtg   1320

gatacaaaac ctatacctag gctgacatcc caaatgtgtg tggcaagtta gatgatgatg   1380

gcacaaaaga cagaacacct tgcttctggc cattgtcagc tcttggaaga gagcacactt   1440

ttagaggagc agctgcaagg agcctgagaa caaaactgga aatgtctgtt atgaaagcct   1500

tcacaggaaa ttctgcaagt ggcaacgtgg gtccattccg tgtgtgtcac tagagctggc   1560

gcaagcccat ggccatggtg aggcagcgtt tccactggaa ctaatctgat acctgcacca   1620

gctcttgcaa ctgtgcagtg ttcccactgc aaactacgga tggggtaaaa gactgctcac   1680

ctcctatttc tcatctaatc tcacacactc tgtttgatga ggctatggag aaacaggtct   1740

tctcatacac taaaggtggg agtacaaaca attcaagccc tgtgcaggac aattaggcaa   1800

tacctatcaa aattatacat gatttttcct gctgacccag caattccact tctgggaata   1860

attgacagat ataggtgcat atgtacaaaa tgatggaaag ctctctggta tatattagta   1920

agtgataaaa caaggtgtaa aatagtgtat atatggctac taccttttgt tttaaaaatg   1980

ggggaaaatg gtggagcttg cggtgagccg agatcgtgcc actgcactcc agcctgggcg   2040

acagagcgag actccgtctc aaaaaaaaaa cagggtgggg tgggggggaa ataatagtac   2100

atactcatat ttacctgtat ctatataaaa cacactatca aggattcaca agaaactaat   2160

acaaatgatc accttataga tggtatgtat tgggggatac tgaggtgagc agggtataag   2220

tggggcaaga cttttcagtg taaacttctt ttaaatttta ttttgatttt tgaataatgt   2280

aaattaactg tcaaataatt aaattaaaaa taaccaattt attaac                  2326


<210>  7841
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  7841

Met Gly Pro His Thr Trp Arg Tyr Ser Ile Ile Ala Lys Lys Lys Asp 
1               5                   10                  15


Asn Phe Ile Glu Pro Ser Cys Phe Thr Val Leu Asn Tyr Tyr His Lys 
            20                  25                  30


Val Pro Thr Ile Tyr Ala Tyr Leu Ile Gly Tyr Phe Val Lys Thr Met 
        35                  40                  45


His Glu Gly His Leu Phe Glu Met Ser Glu His Phe Pro Val Arg Arg 
    50                  55                  60


Ser His Trp Ala Leu Lys Gln Asn His Met Leu Phe Arg Pro Ala Thr 
65                  70                  75                  80


Ala Thr Thr Lys Tyr Ser Ser Val Asn Ser Thr 
                85                  90


<210>  7842
<211>  1440
<212>  DNA
<213>  Homo sapiens

<400>  7842
ctagtatcgc gagatcagga aggtggccga gtgtgtcgcc gcggccatca ggcacttctc     60

cttcctgccc ttgtatgaag aaggatgtgt ttgcttcccc ttgtgccatg attgtaaatt    120

tcctgaggcc tcctcagccc tgcagaactg gctagagcaa tgtatcttag gctcacttaa    180

ggaagctgta gagatgagcc caaggaggga aaccagaaga gccccccagg ctcaccagtt    240

gtttgttggc tccctacaaa catgtcattc aagtggctaa tcttacaaca gcacaaattc    300

atctaaccag aaagagaaga ggaggctcca aaggcacttg actactgagc atcaccctgg    360

acgtgtacaa gtctgcgtcc ttattgtttt cttcattggg ccgaactttc tggtcctcat    420

ccaacagctc ttctatcacg tgttcgaaag tgtcagccaa tgatgtcaag cctcttgaac    480

ctgccttggg cccattcacg ctctccagag tcccatgggt ccgcacacct ggagatactc    540

tattatagca aagaagaaag ataatttcat tgagccatcc tgttttacag gaaattctgc    600

aagtggcaac gtgggtccat tccgtgtgtg tcactagagc tggcgcaagc ccatggccat    660

ggtgaggcag cgtttccact ggaactaatc tgatacctgc accagctctt gcaactgtgc    720

agtgttccca ctgcaaacta cggatgggga ttttccctcc tggtgagtca aaatgaacaa    780

gaaatacccc aggacctccc ttccctcctt ggccattaat gagatgaagg caattaactc    840

acatagtata aatgaatcat ttgaggtgat gactgcattt taggcaaatg atgactttct    900

tggttccatt ggtttgcaag taaaagttac acacattgaa aagacactga aacagatttc    960

ctaaatgctt cattttctgg atgcaccaat gttgacctac tatacatgtt aaatggtttt   1020

aaaatatcac cttaaaataa aggaaacttc cagctactaa ctcagctctg aatgggctat   1080

gaaaggctcc aaaggtatgt gaaaaattac tgttattttg ctttaaaaaa tgtgatgtct   1140

aagagtgtct gcaatgttct aatgcttcaa aacatgtacg taagccttgt ttatctggaa   1200

atcatttctt tctgcttata tcatttataa atagaaaatg ttctgtaata acttaaaata   1260

gttccacata cataatgctt ttagtgtcat aatacttact actggtctat atttaccaac   1320

atttatcaca ttttacaaaa tgaagtagaa gaaaaaaaag acaacgactt tatggccctg   1380

gaattccagt aatggtgacc aacatgtttt aaattccagt aaaggttatg gttacatttc   1440


<210>  7843
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  7843

Met Gly Pro His Thr Trp Arg Tyr Ser Ile Ile Ala Lys Lys Lys Asp 
1               5                   10                  15


Asn Phe Ile Glu Pro Ser Cys Phe Thr Gly Asn Ser Ala Ser Gly Asn 
            20                  25                  30


Val Gly Pro Phe Arg Val Cys His 
        35                  40


<210>  7844
<211>  1282
<212>  DNA
<213>  Homo sapiens

<400>  7844
ctagtatcgc gagatcagga aggtggccga gtgtgtcgcc gcggccatca ggcacttctc     60

cttcctgccc ttgtatgaag aaggatgtgt ttgcttcccc ttgtgccatg attgtaaatt    120

tcctgaggcc tcctcagccc tgcagaactg gctagagcaa tgtatcttag gctcacttaa    180

ggaagctgta gagatgagcc caaggaggga aaccagaaga gccccccagg ctcaccagtt    240

gtttgttggc tccctacaaa catgtcattc aagtggctaa tcttacaaca gcacaaattc    300

atctaaccag aaagagaaga ggaggctcca aaggcacttg actactgagc atcaccctgg    360

acgtgtacaa gtctgcgtcc ttattgtttt cttcattggg ccgaactttc tggtcctcat    420

ccaacagctc ttctatcacg tgttcgaaag tgtcagccaa tgatgtcaag cctcttgaac    480

ctgccttggg cccattcacg ctctccagag tcccatgggt ccgcacacct ggagatactc    540

tattatagca aagaagaaag ataatttcat tgagccatcc tgttttacag gattttccct    600

cctggtgagt caaaatgaac aagaaatacc ccaggacctc ccttccctcc ttggccatta    660

atgagatgaa ggcaattaac tcacatagta taaatgaatc atttgaggtg atgactgcat    720

tttaggcaaa tgatgacttt cttggttcca ttggtttgca agtaaaagtt acacacattg    780

aaaagacact gaaacagatt tcctaaatgc ttcattttct ggatgcacca atgttgacct    840

actatacatg ttaaatggtt ttaaaatatc accttaaaat aaaggaaact tccagctact    900

aactcagctc tgaatgggct atgaaaggct ccaaaggtat gtgaaaaatt actgttattt    960

tgctttaaaa aatgtgatgt ctaagagtgt ctgcaatgtt ctaatgcttc aaaacatgta   1020

cgtaagcctt gtttatctgg aaatcatttc tttctgctta tatcatttat aaatagaaaa   1080

tgttctgtaa taacttaaaa tagttccaca tacataatgc ttttagtgtc ataatactta   1140

ctactggtct atatttacca acatttatca cattttacaa aatgaagtag aagaaaaaaa   1200

agacaacgac tttatggccc tggaattcca gtaatggtga ccaacatgtt ttaaattcca   1260

gtaaaggtta tggttacatt tc                                            1282


<210>  7845
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  7845

Met Gly Pro His Thr Trp Arg Tyr Ser Ile Ile Ala Lys Lys Lys Asp 
1               5                   10                  15


Asn Phe Ile Glu Pro Ser Cys Phe Thr Gly Phe Ser Leu Leu Val Ser 
            20                  25                  30


Gln Asn Glu Gln Glu Ile Pro Gln Asp Leu Pro Ser Leu Leu Gly His 
        35                  40                  45


<210>  7846
<211>  2039
<212>  DNA
<213>  Homo sapiens

<400>  7846
ctagtatcgc gagatcagga aggtggccga gtgtgtcgcc gcggccatca ggcacttctc     60

cttcctgccc ttgtatgaag aaggatgtgt ttgcttcccc ttgtgccatg attgtaaatt    120

tcctgaggcc tcctcagccc tgcagaactg gctagagcaa tgtatcttag gctcacttaa    180

ggaagctgta gagatgagcc caaggaggga aaccagaaga gccccccagg ctcaccagtt    240

gtttgttggc tccctacaaa catgtcattc aagtggctaa tcttacaaca gcacaaattc    300

atctaaccag aaagagaaga ggaggctcca aaggcacttg actactgagc atcaccctgg    360

acgtgtacaa gtctgcgtcc ttattgtttt cttcattggg ccgaactttc tggtcctcat    420

ccaacagctc ttctatcacg tgttcgaaag tgtcagccaa tgatgtcaag cctcttgaac    480

ctgccttggg cccattcacg ctctccagag tcccatgggt ccgcacacct ggagatactc    540

tattatagca aagaagaaag ataatttcat tgagccatcc tgttttacag cacccaacag    600

aatcccttca aagcctcgtg gtctgacacc ctatgctacg tgacttgtga cccatccatt    660

tgtcatgttc ttcgggaatg tggctaaggg gctaagatgt gacttgaaaa gaaaggtaga    720

acaagatcat ctcaaattta ttatcaagga atagttcaga aaacgacttc agaccacaga    780

gacagcagaa cagatggtcc ggcatggata gagcatcaga cactcacaga ctgtgccaac    840

aagagccatc gagtcaaaac agccaaagga aggagggtca tggaatgggt tctctcacac    900

caaactgatg cccagaggcc ctcagcatga ataacaaagg caaccagacc cacaagccat    960

actgagtgga tacaaaacct atacctaggc tgacatccca aatgtgtgtg gcaagttaga   1020

tgatgatggc acaaaagaca gaacaccttg cttctggcca ttgtcagctc ttggaagaga   1080

gcacactttt agaggagcag ctgcaaggag cctgagaaca aaactggaaa tgtctgttat   1140

gaaagccttc acaggaaatt ctgcaagtgg caacgtgggt ccattccgtg tgtgtcacta   1200

gagctggcgc aagcccatgg ccatggtgag gcagcgtttc cactggaact aatctgatac   1260

ctgcaccagc tcttgcaact gtgcagtgtt cccactgcaa actacggatg ggagaggata   1320

aagaacttca atctttaaaa aagagaggat tttccctcct ggtgagtcaa aatgaacaag   1380

aaatacccca ggacctccct tccctccttg gccattaatg agatgaaggc aattaactca   1440

catagtataa atgaatcatt tgaggtgatg actgcatttt aggcaaatga tgactttctt   1500

ggttccattg gtttgcaagt aaaagttaca cacattgaaa agacactgaa acagatttcc   1560

taaatgcttc attttctgga tgcaccaatg ttgacctact atacatgtta aatggtttta   1620

aaatatcacc ttaaaataaa ggaaacttcc agctactaac tcagctctga atgggctatg   1680

aaaggctcca aaggtatgtg aaaaattact gttattttgc tttaaaaaat gtgatgtcta   1740

agagtgtctg caatgttcta atgcttcaaa acatgtacgt aagccttgtt tatctggaaa   1800

tcatttcttt ctgcttatat catttataaa tagaaaatgt tctgtaataa cttaaaatag   1860

ttccacatac ataatgcttt tagtgtcata atacttacta ctggtctata tttaccaaca   1920

tttatcacat tttacaaaat gaagtagaag aaaaaaaaga caacgacttt atggccctgg   1980

aattccagta atggtgacca acatgtttta aattccagta aaggttatgg ttacatttc    2039


<210>  7847
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7847

Met Gly Pro His Thr Trp Arg Tyr Ser Ile Ile Ala Lys Lys Lys Asp 
1               5                   10                  15


Asn Phe Ile Glu Pro Ser Cys Phe Thr Ala Pro Asn Arg Ile Pro Ser 
            20                  25                  30


Lys Pro Arg Gly Leu Thr Pro Tyr Ala Thr 
        35                  40


<210>  7848
<211>  3941
<212>  DNA
<213>  Homo sapiens

<400>  7848
agtggactta caagtccgaa gccaatgtag cttggaaaac ttgggaggcg gaattcctac     60

cgctgggaac tgaaagggtc tgcgacactc tcgggcaggc cgaacccaca tctctaccca    120

tcctgcgccc ctcttctgaa gcgccctcca gggaagttaa gagttttgac tttcggggag    180

tggttgggat gtacgtgggg gattcttgac tcgggttagt ctctggggat gcagagccgg    240

gaagaggaat ggttccacca ggtgagaaga gtgatgacca tccttttcct tactatggtt    300

atttcatact ttggttgcat gaaggctgcc cccatgaaag aagcaaacat ccgaggacaa    360

ggtggcttgg cctacccagg tgtgcggacc catgggactc tggagagcgt gaatgggccc    420

aaggcaggtt caagaggctt gacatcattg gctgacactt tcgaacacgt gatagaagag    480

ctgttggatg aggaccagaa agttcggccc aatgaagaaa acaataagga cgcagacttg    540

tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg agcctcctct tctctttctg    600

ctggaggaat acaaaaatta cctagatgct gcaaacatgt ccatgagggt ccggcgccac    660

tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca gtattagtga gtgggtaacg    720

gcagcagaca aaaagactgc agtggacatg tcgggcggga cggtcacagt ccttgaaaag    780

gtccctgtat caaaaggcca actgaagcaa tacttctacg agaccaagtg caatcccatg    840

ggttacacaa aagaaggctg caggggcata gacaaaaggc attggaactc ccagtgccga    900

actacccagt cgtacgtgcg ggcccttacc atggatagca aaaagagaat tggctggcga    960

ttcataagga tagacacttc ttgtgtatgt acattgacca ttaaaagggg aagatagtgg   1020

atttatgttg tatagattag attatattga gacaaaaatt atctatttgt atatatacat   1080

aacagggtaa attattcagt taagaaaaaa ataattttat gaactgcatg tataaatgaa   1140

gtttatacag tacagtggtt ctacaatcta tttattggac atgtccatga ccagaaggga   1200

aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat tccttgataa tgttgtggtt   1260

tgttgccgtt gccaagaact gaaaacataa aaagttaaaa aaaataataa attgcatgct   1320

gctttaattg tgaattgata ataaactgtc ctctttcaga aaacagaaaa aaaacacaca   1380

cacacacaac aaaaatttga accaaaacat tccgtttaca ttttagacag taagtatctt   1440

cgttcttgtt agtactatat ctgttttact gcttttaact tctgatagcg ttggaattaa   1500

aacaatgtca aggtgctgtt gtcattgctt tactggctta ggggatgggg gatggggggt   1560

atatttttgt ttgttttgtg tttttttttc gtttgtttgt tttgtttttt agttcccaca   1620

gggagtagag atggggaaag aattcctaca atatatattc tggctgataa aagatacatt   1680

tgtatgttgt gaagatgttt gcaatatcga tcagatgact agaaagtgaa taaaaattaa   1740

ggcaactgaa caaaaaaatg ctcacactcc acatcccgtg atgcacctcc caggccccgc   1800

tcattctttg ggcgttggtc agagtaagct gcttttgacg gaaggaccta tgtttgctca   1860

gaacacattc tttccccccc tccccctctg gtctcctctt tgttttgttt taaggaagaa   1920

aaatcagttg cgcgttctga aatattttac cactgctgtg aacaagtgaa cacattgtgt   1980

cacatcatga cactcgtata agcatggaga acagtgattt ttttttagaa cagaaaacaa   2040

caaaaaataa ccccaaaatg aagattattt tttatgagga gtgaacattt gggtaaatca   2100

tggctaagct taaaaaaaac tcatggtgag gcttaacaat gtcttgtaag caaaaggtag   2160

agccctgtat caacccagaa acacctagat cagaacagga atccacattg ccagtgacat   2220

gagactgaac agccaaatgg aggctatgtg gagttggcat tgcatttacc ggcagtgcgg   2280

gaggaatttc tgagtggcca tcccaaggtc taggtggagg tggggcatgg tatttgagac   2340

attccaaaac gaaggcctct gaaggaccct tcagaggtgg ctctggaatg acatgtgtca   2400

agctgcttgg acctcgtgct ttaagtgcct acattatcta actgtgctca agaggttctc   2460

gactggagga ccacactcaa gccgacttat gcccaccatc ccacctctgg ataattttgc   2520

ataaaattgg attagcctgg agcaggttgg gagccaaatg tggcatttgt gatcatgaga   2580

ttgatgcaat gagatagaag atgtttgcta cctgaacact tattgctttg aaactagact   2640

tgaggaaacc agggtttatc ttttgagaac ttttggtaag ggaaaaggga acaggaaaag   2700

aaaccccaaa ctcaggccga atgatcaagg ggacccatag gaaatcttgt ccagagacaa   2760

gacttcggga aggtgtctgg acattcagaa caccaagact tgaaggtgcc ttgctcaatg   2820

gaagaggcca ggacagagct gacaaaattt tgctccccag tgaaggccac agcaaccttc   2880

tgcccatcct gtctgttcat ggagagggtc cctgcctcac ctctgccatt ttgggttagg   2940

agaagtcaag ttgggagcct gaaatagtgg ttcttggaaa aatggatccc cagtgaaaac   3000

tagagctcta agcccattca gcccatttca cacctgaaaa tgttagtgat caccacttgg   3060

accagcatcc ttaagtatca gaaagcccca agcaattgct gcatcttagt agggtgaggg   3120

ataagcaaaa gaggatgttc accataaccc aggaatgaag ataccatcag caaagaattt   3180

caatttgttc agtctttcat ttagagctag tctttcacag taccatctga atacctcttt   3240

gaaagaagga agactttacg tagtgtagat ttgttttgtg ttgtttgaaa atattatctt   3300

tgtaattatt tttaatatgt aaggaatgct tggaatatct gctgtatgtc aactttatgc   3360

agcttccttt tgagggacaa atttaaaaca aacaaccccc catcacaaac ttaaaggatt   3420

gcaagggcca gatctgttaa gtggtttcat aggagacaca tccagcaatt gtgtggtcag   3480

tggctctttt acccaataag atacatcaca gtcacatgct tgatggttta tgttgaccta   3540

agatttattt tgttaaaatc tctctctgtt gtgttcgttc ttgttctgtt ttgttttgtt   3600

ttttaaagtc ttgctgtggt ctctttgtgg cagaagtgtt tcatgcatgg cagcaggcct   3660

gttgcttttt tatggcgatt cccattgaaa atgtaagtaa atgtctgtgg ccttgttctc   3720

tctatggtaa agatattatt caccatgtaa aacaaaaaac aatatttatt gtattttagt   3780

atatttatat aattatgtta ttgaaaaaaa ttggcattaa aacttaaccg catcagaagc   3840

ctattgtaaa tacaagttct atttaagtgt actaattaac atataatata tgttttaaat   3900

atagaatttt taatgttttt aaatatattt tcaaagtaca t                       3941


<210>  7849
<211>  262
<212>  PRT
<213>  Homo sapiens

<400>  7849

Met Gln Ser Arg Glu Glu Glu Trp Phe His Gln Val Arg Arg Val Met 
1               5                   10                  15


Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met Lys 
            20                  25                  30


Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu Ala 
        35                  40                  45


Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly Pro 
    50                  55                  60


Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu His 
65                  70                  75                  80


Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn Glu 
                85                  90                  95


Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu Ser 
            100                 105                 110


Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu Tyr 
        115                 120                 125


Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg His 
    130                 135                 140


Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile Ser 
145                 150                 155                 160


Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser Gly 
                165                 170                 175


Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln Leu 
            180                 185                 190


Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr Lys 
        195                 200                 205


Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys Arg 
    210                 215                 220


Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys Arg 
225                 230                 235                 240


Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr Leu 
                245                 250                 255


Thr Ile Lys Arg Gly Arg 
            260


<210>  7850
<211>  3971
<212>  DNA
<213>  Homo sapiens

<400>  7850
gctccgggtc cccgacgctg ccgccgccgc gcccgggcgc acccgcccgc tcgctgtccc     60

gcgcaccccg tagcgcctcg ggctcccggg ccggacagag gagccagccc ggtgcgcccc    120

tccacctcct gctcgggggg ctttaatgag acacccaccg ctgctgtggg gccggcgggg    180

agcagcaccg cgacggggac cggggctggg cgctggagcc agaatcggaa ccacgatgtg    240

actccgccgc cggggacccg tgaggtttgt gtggaccccg agttccacca ggtgagaaga    300

gtgatgacca tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc    360

cccatgaaag aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc    420

catgggactc tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg    480

gctgacactt tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc    540

aatgaagaaa acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa    600

gtgcctttgg agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct    660

gcaaacatgt ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc    720

gtgtgtgaca gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg    780

tcgggcggga cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa    840

tacttctacg agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata    900

gacaaaaggc attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc    960

atggatagca aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt   1020

acattgacca ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga   1080

gacaaaaatt atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa   1140

ataattttat gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta   1200

tttattggac atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc   1260

tgcattacat tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa   1320

aaagttaaaa aaaataataa attgcatgct gctttaattg tgaattgata ataaactgtc   1380

ctctttcaga aaacagaaaa aaaacacaca cacacacaac aaaaatttga accaaaacat   1440

tccgtttaca ttttagacag taagtatctt cgttcttgtt agtactatat ctgttttact   1500

gcttttaact tctgatagcg ttggaattaa aacaatgtca aggtgctgtt gtcattgctt   1560

tactggctta ggggatgggg gatggggggt atatttttgt ttgttttgtg tttttttttc   1620

gtttgtttgt tttgtttttt agttcccaca gggagtagag atggggaaag aattcctaca   1680

atatatattc tggctgataa aagatacatt tgtatgttgt gaagatgttt gcaatatcga   1740

tcagatgact agaaagtgaa taaaaattaa ggcaactgaa caaaaaaatg ctcacactcc   1800

acatcccgtg atgcacctcc caggccccgc tcattctttg ggcgttggtc agagtaagct   1860

gcttttgacg gaaggaccta tgtttgctca gaacacattc tttccccccc tccccctctg   1920

gtctcctctt tgttttgttt taaggaagaa aaatcagttg cgcgttctga aatattttac   1980

cactgctgtg aacaagtgaa cacattgtgt cacatcatga cactcgtata agcatggaga   2040

acagtgattt ttttttagaa cagaaaacaa caaaaaataa ccccaaaatg aagattattt   2100

tttatgagga gtgaacattt gggtaaatca tggctaagct taaaaaaaac tcatggtgag   2160

gcttaacaat gtcttgtaag caaaaggtag agccctgtat caacccagaa acacctagat   2220

cagaacagga atccacattg ccagtgacat gagactgaac agccaaatgg aggctatgtg   2280

gagttggcat tgcatttacc ggcagtgcgg gaggaatttc tgagtggcca tcccaaggtc   2340

taggtggagg tggggcatgg tatttgagac attccaaaac gaaggcctct gaaggaccct   2400

tcagaggtgg ctctggaatg acatgtgtca agctgcttgg acctcgtgct ttaagtgcct   2460

acattatcta actgtgctca agaggttctc gactggagga ccacactcaa gccgacttat   2520

gcccaccatc ccacctctgg ataattttgc ataaaattgg attagcctgg agcaggttgg   2580

gagccaaatg tggcatttgt gatcatgaga ttgatgcaat gagatagaag atgtttgcta   2640

cctgaacact tattgctttg aaactagact tgaggaaacc agggtttatc ttttgagaac   2700

ttttggtaag ggaaaaggga acaggaaaag aaaccccaaa ctcaggccga atgatcaagg   2760

ggacccatag gaaatcttgt ccagagacaa gacttcggga aggtgtctgg acattcagaa   2820

caccaagact tgaaggtgcc ttgctcaatg gaagaggcca ggacagagct gacaaaattt   2880

tgctccccag tgaaggccac agcaaccttc tgcccatcct gtctgttcat ggagagggtc   2940

cctgcctcac ctctgccatt ttgggttagg agaagtcaag ttgggagcct gaaatagtgg   3000

ttcttggaaa aatggatccc cagtgaaaac tagagctcta agcccattca gcccatttca   3060

cacctgaaaa tgttagtgat caccacttgg accagcatcc ttaagtatca gaaagcccca   3120

agcaattgct gcatcttagt agggtgaggg ataagcaaaa gaggatgttc accataaccc   3180

aggaatgaag ataccatcag caaagaattt caatttgttc agtctttcat ttagagctag   3240

tctttcacag taccatctga atacctcttt gaaagaagga agactttacg tagtgtagat   3300

ttgttttgtg ttgtttgaaa atattatctt tgtaattatt tttaatatgt aaggaatgct   3360

tggaatatct gctgtatgtc aactttatgc agcttccttt tgagggacaa atttaaaaca   3420

aacaaccccc catcacaaac ttaaaggatt gcaagggcca gatctgttaa gtggtttcat   3480

aggagacaca tccagcaatt gtgtggtcag tggctctttt acccaataag atacatcaca   3540

gtcacatgct tgatggttta tgttgaccta agatttattt tgttaaaatc tctctctgtt   3600

gtgttcgttc ttgttctgtt ttgttttgtt ttttaaagtc ttgctgtggt ctctttgtgg   3660

cagaagtgtt tcatgcatgg cagcaggcct gttgcttttt tatggcgatt cccattgaaa   3720

atgtaagtaa atgtctgtgg ccttgttctc tctatggtaa agatattatt caccatgtaa   3780

aacaaaaaac aatatttatt gtattttagt atatttatat aattatgtta ttgaaaaaaa   3840

ttggcattaa aacttaaccg catcagaagc ctattgtaaa tacaagttct atttaagtgt   3900

actaattaac atataatata tgttttaaat atagaatttt taatgttttt aaatatattt   3960

tcaaagtaca t                                                        3971


<210>  7851
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7851

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7852
<211>  4021
<212>  DNA
<213>  Homo sapiens

<400>  7852
ctttcccatt caccgcggag agggctgctc tcgctgccgc tccccccggc gaactagcat     60

gaaatctccc tgcctctgcc gagatcaaat ggagcttctc gctgatgggg tgcgagtatt    120

acctccgcca tgcaatttcc actatcaata atttaacttc tttgctgcag aacagaagga    180

gtacataccg ggcaccaaag actcgcgccc cctcccccct ttaattaagc gaagggaacg    240

tgaaaaaata atagagtgtg ggagttttgg ggccgaagtc tttcccggag cagctgcctt    300

gatggttact ttgacaagta gtgactgaaa agttccacca ggtgagaaga gtgatgacca    360

tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc cccatgaaag    420

aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc catgggactc    480

tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg gctgacactt    540

tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc aatgaagaaa    600

acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg    660

agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct gcaaacatgt    720

ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca    780

gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg tcgggcggga    840

cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa tacttctacg    900

agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata gacaaaaggc    960

attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc atggatagca   1020

aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt acattgacca   1080

ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga gacaaaaatt   1140

atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa ataattttat   1200

gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta tttattggac   1260

atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat   1320

tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa aaagttaaaa   1380

aaaataataa attgcatgct gctttaattg tgaattgata ataaactgtc ctctttcaga   1440

aaacagaaaa aaaacacaca cacacacaac aaaaatttga accaaaacat tccgtttaca   1500

ttttagacag taagtatctt cgttcttgtt agtactatat ctgttttact gcttttaact   1560

tctgatagcg ttggaattaa aacaatgtca aggtgctgtt gtcattgctt tactggctta   1620

ggggatgggg gatggggggt atatttttgt ttgttttgtg tttttttttc gtttgtttgt   1680

tttgtttttt agttcccaca gggagtagag atggggaaag aattcctaca atatatattc   1740

tggctgataa aagatacatt tgtatgttgt gaagatgttt gcaatatcga tcagatgact   1800

agaaagtgaa taaaaattaa ggcaactgaa caaaaaaatg ctcacactcc acatcccgtg   1860

atgcacctcc caggccccgc tcattctttg ggcgttggtc agagtaagct gcttttgacg   1920

gaaggaccta tgtttgctca gaacacattc tttccccccc tccccctctg gtctcctctt   1980

tgttttgttt taaggaagaa aaatcagttg cgcgttctga aatattttac cactgctgtg   2040

aacaagtgaa cacattgtgt cacatcatga cactcgtata agcatggaga acagtgattt   2100

ttttttagaa cagaaaacaa caaaaaataa ccccaaaatg aagattattt tttatgagga   2160

gtgaacattt gggtaaatca tggctaagct taaaaaaaac tcatggtgag gcttaacaat   2220

gtcttgtaag caaaaggtag agccctgtat caacccagaa acacctagat cagaacagga   2280

atccacattg ccagtgacat gagactgaac agccaaatgg aggctatgtg gagttggcat   2340

tgcatttacc ggcagtgcgg gaggaatttc tgagtggcca tcccaaggtc taggtggagg   2400

tggggcatgg tatttgagac attccaaaac gaaggcctct gaaggaccct tcagaggtgg   2460

ctctggaatg acatgtgtca agctgcttgg acctcgtgct ttaagtgcct acattatcta   2520

actgtgctca agaggttctc gactggagga ccacactcaa gccgacttat gcccaccatc   2580

ccacctctgg ataattttgc ataaaattgg attagcctgg agcaggttgg gagccaaatg   2640

tggcatttgt gatcatgaga ttgatgcaat gagatagaag atgtttgcta cctgaacact   2700

tattgctttg aaactagact tgaggaaacc agggtttatc ttttgagaac ttttggtaag   2760

ggaaaaggga acaggaaaag aaaccccaaa ctcaggccga atgatcaagg ggacccatag   2820

gaaatcttgt ccagagacaa gacttcggga aggtgtctgg acattcagaa caccaagact   2880

tgaaggtgcc ttgctcaatg gaagaggcca ggacagagct gacaaaattt tgctccccag   2940

tgaaggccac agcaaccttc tgcccatcct gtctgttcat ggagagggtc cctgcctcac   3000

ctctgccatt ttgggttagg agaagtcaag ttgggagcct gaaatagtgg ttcttggaaa   3060

aatggatccc cagtgaaaac tagagctcta agcccattca gcccatttca cacctgaaaa   3120

tgttagtgat caccacttgg accagcatcc ttaagtatca gaaagcccca agcaattgct   3180

gcatcttagt agggtgaggg ataagcaaaa gaggatgttc accataaccc aggaatgaag   3240

ataccatcag caaagaattt caatttgttc agtctttcat ttagagctag tctttcacag   3300

taccatctga atacctcttt gaaagaagga agactttacg tagtgtagat ttgttttgtg   3360

ttgtttgaaa atattatctt tgtaattatt tttaatatgt aaggaatgct tggaatatct   3420

gctgtatgtc aactttatgc agcttccttt tgagggacaa atttaaaaca aacaaccccc   3480

catcacaaac ttaaaggatt gcaagggcca gatctgttaa gtggtttcat aggagacaca   3540

tccagcaatt gtgtggtcag tggctctttt acccaataag atacatcaca gtcacatgct   3600

tgatggttta tgttgaccta agatttattt tgttaaaatc tctctctgtt gtgttcgttc   3660

ttgttctgtt ttgttttgtt ttttaaagtc ttgctgtggt ctctttgtgg cagaagtgtt   3720

tcatgcatgg cagcaggcct gttgcttttt tatggcgatt cccattgaaa atgtaagtaa   3780

atgtctgtgg ccttgttctc tctatggtaa agatattatt caccatgtaa aacaaaaaac   3840

aatatttatt gtattttagt atatttatat aattatgtta ttgaaaaaaa ttggcattaa   3900

aacttaaccg catcagaagc ctattgtaaa tacaagttct atttaagtgt actaattaac   3960

atataatata tgttttaaat atagaatttt taatgttttt aaatatattt tcaaagtaca   4020

t                                                                   4021


<210>  7853
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7853

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7854
<211>  3825
<212>  DNA
<213>  Homo sapiens

<400>  7854
tttttttttc ccttctgtcc tccctccccg cgagtttcgg gcgctggctt agagggttcc     60

cgctttctca agggaagggg agctgccgag accgcgctcc gctccccagc cgggccggat    120

gcctcactga gcccagttcc accaggtgag aagagtgatg accatccttt tccttactat    180

ggttatttca tactttggtt gcatgaaggc tgcccccatg aaagaagcaa acatccgagg    240

acaaggtggc ttggcctacc caggtgtgcg gacccatggg actctggaga gcgtgaatgg    300

gcccaaggca ggttcaagag gcttgacatc attggctgac actttcgaac acgtgataga    360

agagctgttg gatgaggacc agaaagttcg gcccaatgaa gaaaacaata aggacgcaga    420

cttgtacacg tccagggtga tgctcagtag tcaagtgcct ttggagcctc ctcttctctt    480

tctgctggag gaatacaaaa attacctaga tgctgcaaac atgtccatga gggtccggcg    540

ccactctgac cctgcccgcc gaggggagct gagcgtgtgt gacagtatta gtgagtgggt    600

aacggcagca gacaaaaaga ctgcagtgga catgtcgggc gggacggtca cagtccttga    660

aaaggtccct gtatcaaaag gccaactgaa gcaatacttc tacgagacca agtgcaatcc    720

catgggttac acaaaagaag gctgcagggg catagacaaa aggcattgga actcccagtg    780

ccgaactacc cagtcgtacg tgcgggccct taccatggat agcaaaaaga gaattggctg    840

gcgattcata aggatagaca cttcttgtgt atgtacattg accattaaaa ggggaagata    900

gtggatttat gttgtataga ttagattata ttgagacaaa aattatctat ttgtatatat    960

acataacagg gtaaattatt cagttaagaa aaaaataatt ttatgaactg catgtataaa   1020

tgaagtttat acagtacagt ggttctacaa tctatttatt ggacatgtcc atgaccagaa   1080

gggaaacagt catttgcgca caacttaaaa agtctgcatt acattccttg ataatgttgt   1140

ggtttgttgc cgttgccaag aactgaaaac ataaaaagtt aaaaaaaata ataaattgca   1200

tgctgcttta attgtgaatt gataataaac tgtcctcttt cagaaaacag aaaaaaaaca   1260

cacacacaca caacaaaaat ttgaaccaaa acattccgtt tacattttag acagtaagta   1320

tcttcgttct tgttagtact atatctgttt tactgctttt aacttctgat agcgttggaa   1380

ttaaaacaat gtcaaggtgc tgttgtcatt gctttactgg cttaggggat gggggatggg   1440

gggtatattt ttgtttgttt tgtgtttttt tttcgtttgt ttgttttgtt ttttagttcc   1500

cacagggagt agagatgggg aaagaattcc tacaatatat attctggctg ataaaagata   1560

catttgtatg ttgtgaagat gtttgcaata tcgatcagat gactagaaag tgaataaaaa   1620

ttaaggcaac tgaacaaaaa aatgctcaca ctccacatcc cgtgatgcac ctcccaggcc   1680

ccgctcattc tttgggcgtt ggtcagagta agctgctttt gacggaagga cctatgtttg   1740

ctcagaacac attctttccc cccctccccc tctggtctcc tctttgtttt gttttaagga   1800

agaaaaatca gttgcgcgtt ctgaaatatt ttaccactgc tgtgaacaag tgaacacatt   1860

gtgtcacatc atgacactcg tataagcatg gagaacagtg attttttttt agaacagaaa   1920

acaacaaaaa ataaccccaa aatgaagatt attttttatg aggagtgaac atttgggtaa   1980

atcatggcta agcttaaaaa aaactcatgg tgaggcttaa caatgtcttg taagcaaaag   2040

gtagagccct gtatcaaccc agaaacacct agatcagaac aggaatccac attgccagtg   2100

acatgagact gaacagccaa atggaggcta tgtggagttg gcattgcatt taccggcagt   2160

gcgggaggaa tttctgagtg gccatcccaa ggtctaggtg gaggtggggc atggtatttg   2220

agacattcca aaacgaaggc ctctgaagga cccttcagag gtggctctgg aatgacatgt   2280

gtcaagctgc ttggacctcg tgctttaagt gcctacatta tctaactgtg ctcaagaggt   2340

tctcgactgg aggaccacac tcaagccgac ttatgcccac catcccacct ctggataatt   2400

ttgcataaaa ttggattagc ctggagcagg ttgggagcca aatgtggcat ttgtgatcat   2460

gagattgatg caatgagata gaagatgttt gctacctgaa cacttattgc tttgaaacta   2520

gacttgagga aaccagggtt tatcttttga gaacttttgg taagggaaaa gggaacagga   2580

aaagaaaccc caaactcagg ccgaatgatc aaggggaccc ataggaaatc ttgtccagag   2640

acaagacttc gggaaggtgt ctggacattc agaacaccaa gacttgaagg tgccttgctc   2700

aatggaagag gccaggacag agctgacaaa attttgctcc ccagtgaagg ccacagcaac   2760

cttctgccca tcctgtctgt tcatggagag ggtccctgcc tcacctctgc cattttgggt   2820

taggagaagt caagttggga gcctgaaata gtggttcttg gaaaaatgga tccccagtga   2880

aaactagagc tctaagccca ttcagcccat ttcacacctg aaaatgttag tgatcaccac   2940

ttggaccagc atccttaagt atcagaaagc cccaagcaat tgctgcatct tagtagggtg   3000

agggataagc aaaagaggat gttcaccata acccaggaat gaagatacca tcagcaaaga   3060

atttcaattt gttcagtctt tcatttagag ctagtctttc acagtaccat ctgaatacct   3120

ctttgaaaga aggaagactt tacgtagtgt agatttgttt tgtgttgttt gaaaatatta   3180

tctttgtaat tatttttaat atgtaaggaa tgcttggaat atctgctgta tgtcaacttt   3240

atgcagcttc cttttgaggg acaaatttaa aacaaacaac cccccatcac aaacttaaag   3300

gattgcaagg gccagatctg ttaagtggtt tcataggaga cacatccagc aattgtgtgg   3360

tcagtggctc ttttacccaa taagatacat cacagtcaca tgcttgatgg tttatgttga   3420

cctaagattt attttgttaa aatctctctc tgttgtgttc gttcttgttc tgttttgttt   3480

tgttttttaa agtcttgctg tggtctcttt gtggcagaag tgtttcatgc atggcagcag   3540

gcctgttgct tttttatggc gattcccatt gaaaatgtaa gtaaatgtct gtggccttgt   3600

tctctctatg gtaaagatat tattcaccat gtaaaacaaa aaacaatatt tattgtattt   3660

tagtatattt atataattat gttattgaaa aaaattggca ttaaaactta accgcatcag   3720

aagcctattg taaatacaag ttctatttaa gtgtactaat taacatataa tatatgtttt   3780

aaatatagaa tttttaatgt ttttaaatat attttcaaag tacat                   3825


<210>  7855
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7855

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7856
<211>  3769
<212>  DNA
<213>  Homo sapiens

<400>  7856
gtgtgtaatc cgggcgatag gagtccattc agcaccttgg acagagccaa cggatttgtc     60

cgaggtggcg gtacccccag ttccaccagg tgagaagagt gatgaccatc cttttcctta    120

ctatggttat ttcatacttt ggttgcatga aggctgcccc catgaaagaa gcaaacatcc    180

gaggacaagg tggcttggcc tacccaggtg tgcggaccca tgggactctg gagagcgtga    240

atgggcccaa ggcaggttca agaggcttga catcattggc tgacactttc gaacacgtga    300

tagaagagct gttggatgag gaccagaaag ttcggcccaa tgaagaaaac aataaggacg    360

cagacttgta cacgtccagg gtgatgctca gtagtcaagt gcctttggag cctcctcttc    420

tctttctgct ggaggaatac aaaaattacc tagatgctgc aaacatgtcc atgagggtcc    480

ggcgccactc tgaccctgcc cgccgagggg agctgagcgt gtgtgacagt attagtgagt    540

gggtaacggc agcagacaaa aagactgcag tggacatgtc gggcgggacg gtcacagtcc    600

ttgaaaaggt ccctgtatca aaaggccaac tgaagcaata cttctacgag accaagtgca    660

atcccatggg ttacacaaaa gaaggctgca ggggcataga caaaaggcat tggaactccc    720

agtgccgaac tacccagtcg tacgtgcggg cccttaccat ggatagcaaa aagagaattg    780

gctggcgatt cataaggata gacacttctt gtgtatgtac attgaccatt aaaaggggaa    840

gatagtggat ttatgttgta tagattagat tatattgaga caaaaattat ctatttgtat    900

atatacataa cagggtaaat tattcagtta agaaaaaaat aattttatga actgcatgta    960

taaatgaagt ttatacagta cagtggttct acaatctatt tattggacat gtccatgacc   1020

agaagggaaa cagtcatttg cgcacaactt aaaaagtctg cattacattc cttgataatg   1080

ttgtggtttg ttgccgttgc caagaactga aaacataaaa agttaaaaaa aataataaat   1140

tgcatgctgc tttaattgtg aattgataat aaactgtcct ctttcagaaa acagaaaaaa   1200

aacacacaca cacacaacaa aaatttgaac caaaacattc cgtttacatt ttagacagta   1260

agtatcttcg ttcttgttag tactatatct gttttactgc ttttaacttc tgatagcgtt   1320

ggaattaaaa caatgtcaag gtgctgttgt cattgcttta ctggcttagg ggatggggga   1380

tggggggtat atttttgttt gttttgtgtt tttttttcgt ttgtttgttt tgttttttag   1440

ttcccacagg gagtagagat ggggaaagaa ttcctacaat atatattctg gctgataaaa   1500

gatacatttg tatgttgtga agatgtttgc aatatcgatc agatgactag aaagtgaata   1560

aaaattaagg caactgaaca aaaaaatgct cacactccac atcccgtgat gcacctccca   1620

ggccccgctc attctttggg cgttggtcag agtaagctgc ttttgacgga aggacctatg   1680

tttgctcaga acacattctt tccccccctc cccctctggt ctcctctttg ttttgtttta   1740

aggaagaaaa atcagttgcg cgttctgaaa tattttacca ctgctgtgaa caagtgaaca   1800

cattgtgtca catcatgaca ctcgtataag catggagaac agtgattttt ttttagaaca   1860

gaaaacaaca aaaaataacc ccaaaatgaa gattattttt tatgaggagt gaacatttgg   1920

gtaaatcatg gctaagctta aaaaaaactc atggtgaggc ttaacaatgt cttgtaagca   1980

aaaggtagag ccctgtatca acccagaaac acctagatca gaacaggaat ccacattgcc   2040

agtgacatga gactgaacag ccaaatggag gctatgtgga gttggcattg catttaccgg   2100

cagtgcggga ggaatttctg agtggccatc ccaaggtcta ggtggaggtg gggcatggta   2160

tttgagacat tccaaaacga aggcctctga aggacccttc agaggtggct ctggaatgac   2220

atgtgtcaag ctgcttggac ctcgtgcttt aagtgcctac attatctaac tgtgctcaag   2280

aggttctcga ctggaggacc acactcaagc cgacttatgc ccaccatccc acctctggat   2340

aattttgcat aaaattggat tagcctggag caggttggga gccaaatgtg gcatttgtga   2400

tcatgagatt gatgcaatga gatagaagat gtttgctacc tgaacactta ttgctttgaa   2460

actagacttg aggaaaccag ggtttatctt ttgagaactt ttggtaaggg aaaagggaac   2520

aggaaaagaa accccaaact caggccgaat gatcaagggg acccatagga aatcttgtcc   2580

agagacaaga cttcgggaag gtgtctggac attcagaaca ccaagacttg aaggtgcctt   2640

gctcaatgga agaggccagg acagagctga caaaattttg ctccccagtg aaggccacag   2700

caaccttctg cccatcctgt ctgttcatgg agagggtccc tgcctcacct ctgccatttt   2760

gggttaggag aagtcaagtt gggagcctga aatagtggtt cttggaaaaa tggatcccca   2820

gtgaaaacta gagctctaag cccattcagc ccatttcaca cctgaaaatg ttagtgatca   2880

ccacttggac cagcatcctt aagtatcaga aagccccaag caattgctgc atcttagtag   2940

ggtgagggat aagcaaaaga ggatgttcac cataacccag gaatgaagat accatcagca   3000

aagaatttca atttgttcag tctttcattt agagctagtc tttcacagta ccatctgaat   3060

acctctttga aagaaggaag actttacgta gtgtagattt gttttgtgtt gtttgaaaat   3120

attatctttg taattatttt taatatgtaa ggaatgcttg gaatatctgc tgtatgtcaa   3180

ctttatgcag cttccttttg agggacaaat ttaaaacaaa caacccccca tcacaaactt   3240

aaaggattgc aagggccaga tctgttaagt ggtttcatag gagacacatc cagcaattgt   3300

gtggtcagtg gctcttttac ccaataagat acatcacagt cacatgcttg atggtttatg   3360

ttgacctaag atttattttg ttaaaatctc tctctgttgt gttcgttctt gttctgtttt   3420

gttttgtttt ttaaagtctt gctgtggtct ctttgtggca gaagtgtttc atgcatggca   3480

gcaggcctgt tgctttttta tggcgattcc cattgaaaat gtaagtaaat gtctgtggcc   3540

ttgttctctc tatggtaaag atattattca ccatgtaaaa caaaaaacaa tatttattgt   3600

attttagtat atttatataa ttatgttatt gaaaaaaatt ggcattaaaa cttaaccgca   3660

tcagaagcct attgtaaata caagttctat ttaagtgtac taattaacat ataatatatg   3720

ttttaaatat agaattttta atgtttttaa atatattttc aaagtacat               3769


<210>  7857
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7857

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7858
<211>  3984
<212>  DNA
<213>  Homo sapiens

<400>  7858
gtgtgtaatc cgggcgatag gagtccattc agcaccttgg acagagccaa cggatttgtc     60

cgaggtggcg gtacccccag gtagtcttct tggccccgct gtaaagccaa ccctgtgtcg    120

cccttaaaaa gcgtcttttc tgaggttcgg ctcacactga gatcggggct ggagagagag    180

tcagattttg gagcggagcg tttggaaagc gagccccagt ttggtcccct cattgagctc    240

gctgaagttg gcttcctagc ggtgtaggct ggaatagact cttggcaagc tccggttcca    300

ccaggtgaga agagtgatga ccatcctttt ccttactatg gttatttcat actttggttg    360

catgaaggct gcccccatga aagaagcaaa catccgagga caaggtggct tggcctaccc    420

aggtgtgcgg acccatggga ctctggagag cgtgaatggg cccaaggcag gttcaagagg    480

cttgacatca ttggctgaca ctttcgaaca cgtgatagaa gagctgttgg atgaggacca    540

gaaagttcgg cccaatgaag aaaacaataa ggacgcagac ttgtacacgt ccagggtgat    600

gctcagtagt caagtgcctt tggagcctcc tcttctcttt ctgctggagg aatacaaaaa    660

ttacctagat gctgcaaaca tgtccatgag ggtccggcgc cactctgacc ctgcccgccg    720

aggggagctg agcgtgtgtg acagtattag tgagtgggta acggcagcag acaaaaagac    780

tgcagtggac atgtcgggcg ggacggtcac agtccttgaa aaggtccctg tatcaaaagg    840

ccaactgaag caatacttct acgagaccaa gtgcaatccc atgggttaca caaaagaagg    900

ctgcaggggc atagacaaaa ggcattggaa ctcccagtgc cgaactaccc agtcgtacgt    960

gcgggccctt accatggata gcaaaaagag aattggctgg cgattcataa ggatagacac   1020

ttcttgtgta tgtacattga ccattaaaag gggaagatag tggatttatg ttgtatagat   1080

tagattatat tgagacaaaa attatctatt tgtatatata cataacaggg taaattattc   1140

agttaagaaa aaaataattt tatgaactgc atgtataaat gaagtttata cagtacagtg   1200

gttctacaat ctatttattg gacatgtcca tgaccagaag ggaaacagtc atttgcgcac   1260

aacttaaaaa gtctgcatta cattccttga taatgttgtg gtttgttgcc gttgccaaga   1320

actgaaaaca taaaaagtta aaaaaaataa taaattgcat gctgctttaa ttgtgaattg   1380

ataataaact gtcctctttc agaaaacaga aaaaaaacac acacacacac aacaaaaatt   1440

tgaaccaaaa cattccgttt acattttaga cagtaagtat cttcgttctt gttagtacta   1500

tatctgtttt actgctttta acttctgata gcgttggaat taaaacaatg tcaaggtgct   1560

gttgtcattg ctttactggc ttaggggatg ggggatgggg ggtatatttt tgtttgtttt   1620

gtgttttttt ttcgtttgtt tgttttgttt tttagttccc acagggagta gagatgggga   1680

aagaattcct acaatatata ttctggctga taaaagatac atttgtatgt tgtgaagatg   1740

tttgcaatat cgatcagatg actagaaagt gaataaaaat taaggcaact gaacaaaaaa   1800

atgctcacac tccacatccc gtgatgcacc tcccaggccc cgctcattct ttgggcgttg   1860

gtcagagtaa gctgcttttg acggaaggac ctatgtttgc tcagaacaca ttctttcccc   1920

ccctccccct ctggtctcct ctttgttttg ttttaaggaa gaaaaatcag ttgcgcgttc   1980

tgaaatattt taccactgct gtgaacaagt gaacacattg tgtcacatca tgacactcgt   2040

ataagcatgg agaacagtga ttttttttta gaacagaaaa caacaaaaaa taaccccaaa   2100

atgaagatta ttttttatga ggagtgaaca tttgggtaaa tcatggctaa gcttaaaaaa   2160

aactcatggt gaggcttaac aatgtcttgt aagcaaaagg tagagccctg tatcaaccca   2220

gaaacaccta gatcagaaca ggaatccaca ttgccagtga catgagactg aacagccaaa   2280

tggaggctat gtggagttgg cattgcattt accggcagtg cgggaggaat ttctgagtgg   2340

ccatcccaag gtctaggtgg aggtggggca tggtatttga gacattccaa aacgaaggcc   2400

tctgaaggac ccttcagagg tggctctgga atgacatgtg tcaagctgct tggacctcgt   2460

gctttaagtg cctacattat ctaactgtgc tcaagaggtt ctcgactgga ggaccacact   2520

caagccgact tatgcccacc atcccacctc tggataattt tgcataaaat tggattagcc   2580

tggagcaggt tgggagccaa atgtggcatt tgtgatcatg agattgatgc aatgagatag   2640

aagatgtttg ctacctgaac acttattgct ttgaaactag acttgaggaa accagggttt   2700

atcttttgag aacttttggt aagggaaaag ggaacaggaa aagaaacccc aaactcaggc   2760

cgaatgatca aggggaccca taggaaatct tgtccagaga caagacttcg ggaaggtgtc   2820

tggacattca gaacaccaag acttgaaggt gccttgctca atggaagagg ccaggacaga   2880

gctgacaaaa ttttgctccc cagtgaaggc cacagcaacc ttctgcccat cctgtctgtt   2940

catggagagg gtccctgcct cacctctgcc attttgggtt aggagaagtc aagttgggag   3000

cctgaaatag tggttcttgg aaaaatggat ccccagtgaa aactagagct ctaagcccat   3060

tcagcccatt tcacacctga aaatgttagt gatcaccact tggaccagca tccttaagta   3120

tcagaaagcc ccaagcaatt gctgcatctt agtagggtga gggataagca aaagaggatg   3180

ttcaccataa cccaggaatg aagataccat cagcaaagaa tttcaatttg ttcagtcttt   3240

catttagagc tagtctttca cagtaccatc tgaatacctc tttgaaagaa ggaagacttt   3300

acgtagtgta gatttgtttt gtgttgtttg aaaatattat ctttgtaatt atttttaata   3360

tgtaaggaat gcttggaata tctgctgtat gtcaacttta tgcagcttcc ttttgaggga   3420

caaatttaaa acaaacaacc ccccatcaca aacttaaagg attgcaaggg ccagatctgt   3480

taagtggttt cataggagac acatccagca attgtgtggt cagtggctct tttacccaat   3540

aagatacatc acagtcacat gcttgatggt ttatgttgac ctaagattta ttttgttaaa   3600

atctctctct gttgtgttcg ttcttgttct gttttgtttt gttttttaaa gtcttgctgt   3660

ggtctctttg tggcagaagt gtttcatgca tggcagcagg cctgttgctt ttttatggcg   3720

attcccattg aaaatgtaag taaatgtctg tggccttgtt ctctctatgg taaagatatt   3780

attcaccatg taaaacaaaa aacaatattt attgtatttt agtatattta tataattatg   3840

ttattgaaaa aaattggcat taaaacttaa ccgcatcaga agcctattgt aaatacaagt   3900

tctatttaag tgtactaatt aacatataat atatgtttta aatatagaat ttttaatgtt   3960

tttaaatata ttttcaaagt acat                                          3984


<210>  7859
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7859

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7860
<211>  4067
<212>  DNA
<213>  Homo sapiens

<400>  7860
gtgtgtaatc cgggcgatag gagtccattc agcaccttgg acagagccaa cggatttgtc     60

cgaggtggcg gtacccccag gtagtcttct tggccccgct gtaaagccaa ccctgtgtcg    120

cccttaaaaa gcgtcttttc tgaggttcgg ctcacactga gatcggggct ggagagagag    180

tcagattttg gagcggagcg tttggaaagc gagccccagt ttggtcccct cattgagctc    240

gctgaagttg gcttcctagc ggtgtaggct ggaatagact cttggcaagc tccgggttgg    300

tatactgggt taactttggg aaatgcaagt gtttatctcc aggatctagc caccggggtg    360

gtgtaagccg caaagaagtt ccaccaggtg agaagagtga tgaccatcct tttccttact    420

atggttattt catactttgg ttgcatgaag gctgccccca tgaaagaagc aaacatccga    480

ggacaaggtg gcttggccta cccaggtgtg cggacccatg ggactctgga gagcgtgaat    540

gggcccaagg caggttcaag aggcttgaca tcattggctg acactttcga acacgtgata    600

gaagagctgt tggatgagga ccagaaagtt cggcccaatg aagaaaacaa taaggacgca    660

gacttgtaca cgtccagggt gatgctcagt agtcaagtgc ctttggagcc tcctcttctc    720

tttctgctgg aggaatacaa aaattaccta gatgctgcaa acatgtccat gagggtccgg    780

cgccactctg accctgcccg ccgaggggag ctgagcgtgt gtgacagtat tagtgagtgg    840

gtaacggcag cagacaaaaa gactgcagtg gacatgtcgg gcgggacggt cacagtcctt    900

gaaaaggtcc ctgtatcaaa aggccaactg aagcaatact tctacgagac caagtgcaat    960

cccatgggtt acacaaaaga aggctgcagg ggcatagaca aaaggcattg gaactcccag   1020

tgccgaacta cccagtcgta cgtgcgggcc cttaccatgg atagcaaaaa gagaattggc   1080

tggcgattca taaggataga cacttcttgt gtatgtacat tgaccattaa aaggggaaga   1140

tagtggattt atgttgtata gattagatta tattgagaca aaaattatct atttgtatat   1200

atacataaca gggtaaatta ttcagttaag aaaaaaataa ttttatgaac tgcatgtata   1260

aatgaagttt atacagtaca gtggttctac aatctattta ttggacatgt ccatgaccag   1320

aagggaaaca gtcatttgcg cacaacttaa aaagtctgca ttacattcct tgataatgtt   1380

gtggtttgtt gccgttgcca agaactgaaa acataaaaag ttaaaaaaaa taataaattg   1440

catgctgctt taattgtgaa ttgataataa actgtcctct ttcagaaaac agaaaaaaaa   1500

cacacacaca cacaacaaaa atttgaacca aaacattccg tttacatttt agacagtaag   1560

tatcttcgtt cttgttagta ctatatctgt tttactgctt ttaacttctg atagcgttgg   1620

aattaaaaca atgtcaaggt gctgttgtca ttgctttact ggcttagggg atgggggatg   1680

gggggtatat ttttgtttgt tttgtgtttt tttttcgttt gtttgttttg ttttttagtt   1740

cccacaggga gtagagatgg ggaaagaatt cctacaatat atattctggc tgataaaaga   1800

tacatttgta tgttgtgaag atgtttgcaa tatcgatcag atgactagaa agtgaataaa   1860

aattaaggca actgaacaaa aaaatgctca cactccacat cccgtgatgc acctcccagg   1920

ccccgctcat tctttgggcg ttggtcagag taagctgctt ttgacggaag gacctatgtt   1980

tgctcagaac acattctttc cccccctccc cctctggtct cctctttgtt ttgttttaag   2040

gaagaaaaat cagttgcgcg ttctgaaata ttttaccact gctgtgaaca agtgaacaca   2100

ttgtgtcaca tcatgacact cgtataagca tggagaacag tgattttttt ttagaacaga   2160

aaacaacaaa aaataacccc aaaatgaaga ttatttttta tgaggagtga acatttgggt   2220

aaatcatggc taagcttaaa aaaaactcat ggtgaggctt aacaatgtct tgtaagcaaa   2280

aggtagagcc ctgtatcaac ccagaaacac ctagatcaga acaggaatcc acattgccag   2340

tgacatgaga ctgaacagcc aaatggaggc tatgtggagt tggcattgca tttaccggca   2400

gtgcgggagg aatttctgag tggccatccc aaggtctagg tggaggtggg gcatggtatt   2460

tgagacattc caaaacgaag gcctctgaag gacccttcag aggtggctct ggaatgacat   2520

gtgtcaagct gcttggacct cgtgctttaa gtgcctacat tatctaactg tgctcaagag   2580

gttctcgact ggaggaccac actcaagccg acttatgccc accatcccac ctctggataa   2640

ttttgcataa aattggatta gcctggagca ggttgggagc caaatgtggc atttgtgatc   2700

atgagattga tgcaatgaga tagaagatgt ttgctacctg aacacttatt gctttgaaac   2760

tagacttgag gaaaccaggg tttatctttt gagaactttt ggtaagggaa aagggaacag   2820

gaaaagaaac cccaaactca ggccgaatga tcaaggggac ccataggaaa tcttgtccag   2880

agacaagact tcgggaaggt gtctggacat tcagaacacc aagacttgaa ggtgccttgc   2940

tcaatggaag aggccaggac agagctgaca aaattttgct ccccagtgaa ggccacagca   3000

accttctgcc catcctgtct gttcatggag agggtccctg cctcacctct gccattttgg   3060

gttaggagaa gtcaagttgg gagcctgaaa tagtggttct tggaaaaatg gatccccagt   3120

gaaaactaga gctctaagcc cattcagccc atttcacacc tgaaaatgtt agtgatcacc   3180

acttggacca gcatccttaa gtatcagaaa gccccaagca attgctgcat cttagtaggg   3240

tgagggataa gcaaaagagg atgttcacca taacccagga atgaagatac catcagcaaa   3300

gaatttcaat ttgttcagtc tttcatttag agctagtctt tcacagtacc atctgaatac   3360

ctctttgaaa gaaggaagac tttacgtagt gtagatttgt tttgtgttgt ttgaaaatat   3420

tatctttgta attattttta atatgtaagg aatgcttgga atatctgctg tatgtcaact   3480

ttatgcagct tccttttgag ggacaaattt aaaacaaaca accccccatc acaaacttaa   3540

aggattgcaa gggccagatc tgttaagtgg tttcatagga gacacatcca gcaattgtgt   3600

ggtcagtggc tcttttaccc aataagatac atcacagtca catgcttgat ggtttatgtt   3660

gacctaagat ttattttgtt aaaatctctc tctgttgtgt tcgttcttgt tctgttttgt   3720

tttgtttttt aaagtcttgc tgtggtctct ttgtggcaga agtgtttcat gcatggcagc   3780

aggcctgttg cttttttatg gcgattccca ttgaaaatgt aagtaaatgt ctgtggcctt   3840

gttctctcta tggtaaagat attattcacc atgtaaaaca aaaaacaata tttattgtat   3900

tttagtatat ttatataatt atgttattga aaaaaattgg cattaaaact taaccgcatc   3960

agaagcctat tgtaaataca agttctattt aagtgtacta attaacatat aatatatgtt   4020

ttaaatatag aatttttaat gtttttaaat atattttcaa agtacat                 4067


<210>  7861
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7861

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7862
<211>  4027
<212>  DNA
<213>  Homo sapiens

<400>  7862
ggcaatcatt ggtaacctcg ctcattcatt agaatcacgt aagaactcaa aaggaaacgt     60

gtctctcgga gtgagggcgt ttgcgtaaat ctataggttt ttcgacatcg atgccagttg    120

ctttgtcttc tgtagtcgcc aaggtggttg agagtttaag cttgcggata ttgcaaaggg    180

ttattagatt cataagtcac accaagtggt gggcgatcca ctgagcaaag ccgaacttct    240

cacatgatga cttcaaacaa gacacattac cttccagcat ctgttgggga gacgagattt    300

taagacactt gagtctccag gacagcaaag gcacaatgtt ccaccaggtg agaagagtga    360

tgaccatcct tttccttact atggttattt catactttgg ttgcatgaag gctgccccca    420

tgaaagaagc aaacatccga ggacaaggtg gcttggccta cccaggtgtg cggacccatg    480

ggactctgga gagcgtgaat gggcccaagg caggttcaag aggcttgaca tcattggctg    540

acactttcga acacgtgata gaagagctgt tggatgagga ccagaaagtt cggcccaatg    600

aagaaaacaa taaggacgca gacttgtaca cgtccagggt gatgctcagt agtcaagtgc    660

ctttggagcc tcctcttctc tttctgctgg aggaatacaa aaattaccta gatgctgcaa    720

acatgtccat gagggtccgg cgccactctg accctgcccg ccgaggggag ctgagcgtgt    780

gtgacagtat tagtgagtgg gtaacggcag cagacaaaaa gactgcagtg gacatgtcgg    840

gcgggacggt cacagtcctt gaaaaggtcc ctgtatcaaa aggccaactg aagcaatact    900

tctacgagac caagtgcaat cccatgggtt acacaaaaga aggctgcagg ggcatagaca    960

aaaggcattg gaactcccag tgccgaacta cccagtcgta cgtgcgggcc cttaccatgg   1020

atagcaaaaa gagaattggc tggcgattca taaggataga cacttcttgt gtatgtacat   1080

tgaccattaa aaggggaaga tagtggattt atgttgtata gattagatta tattgagaca   1140

aaaattatct atttgtatat atacataaca gggtaaatta ttcagttaag aaaaaaataa   1200

ttttatgaac tgcatgtata aatgaagttt atacagtaca gtggttctac aatctattta   1260

ttggacatgt ccatgaccag aagggaaaca gtcatttgcg cacaacttaa aaagtctgca   1320

ttacattcct tgataatgtt gtggtttgtt gccgttgcca agaactgaaa acataaaaag   1380

ttaaaaaaaa taataaattg catgctgctt taattgtgaa ttgataataa actgtcctct   1440

ttcagaaaac agaaaaaaaa cacacacaca cacaacaaaa atttgaacca aaacattccg   1500

tttacatttt agacagtaag tatcttcgtt cttgttagta ctatatctgt tttactgctt   1560

ttaacttctg atagcgttgg aattaaaaca atgtcaaggt gctgttgtca ttgctttact   1620

ggcttagggg atgggggatg gggggtatat ttttgtttgt tttgtgtttt tttttcgttt   1680

gtttgttttg ttttttagtt cccacaggga gtagagatgg ggaaagaatt cctacaatat   1740

atattctggc tgataaaaga tacatttgta tgttgtgaag atgtttgcaa tatcgatcag   1800

atgactagaa agtgaataaa aattaaggca actgaacaaa aaaatgctca cactccacat   1860

cccgtgatgc acctcccagg ccccgctcat tctttgggcg ttggtcagag taagctgctt   1920

ttgacggaag gacctatgtt tgctcagaac acattctttc cccccctccc cctctggtct   1980

cctctttgtt ttgttttaag gaagaaaaat cagttgcgcg ttctgaaata ttttaccact   2040

gctgtgaaca agtgaacaca ttgtgtcaca tcatgacact cgtataagca tggagaacag   2100

tgattttttt ttagaacaga aaacaacaaa aaataacccc aaaatgaaga ttatttttta   2160

tgaggagtga acatttgggt aaatcatggc taagcttaaa aaaaactcat ggtgaggctt   2220

aacaatgtct tgtaagcaaa aggtagagcc ctgtatcaac ccagaaacac ctagatcaga   2280

acaggaatcc acattgccag tgacatgaga ctgaacagcc aaatggaggc tatgtggagt   2340

tggcattgca tttaccggca gtgcgggagg aatttctgag tggccatccc aaggtctagg   2400

tggaggtggg gcatggtatt tgagacattc caaaacgaag gcctctgaag gacccttcag   2460

aggtggctct ggaatgacat gtgtcaagct gcttggacct cgtgctttaa gtgcctacat   2520

tatctaactg tgctcaagag gttctcgact ggaggaccac actcaagccg acttatgccc   2580

accatcccac ctctggataa ttttgcataa aattggatta gcctggagca ggttgggagc   2640

caaatgtggc atttgtgatc atgagattga tgcaatgaga tagaagatgt ttgctacctg   2700

aacacttatt gctttgaaac tagacttgag gaaaccaggg tttatctttt gagaactttt   2760

ggtaagggaa aagggaacag gaaaagaaac cccaaactca ggccgaatga tcaaggggac   2820

ccataggaaa tcttgtccag agacaagact tcgggaaggt gtctggacat tcagaacacc   2880

aagacttgaa ggtgccttgc tcaatggaag aggccaggac agagctgaca aaattttgct   2940

ccccagtgaa ggccacagca accttctgcc catcctgtct gttcatggag agggtccctg   3000

cctcacctct gccattttgg gttaggagaa gtcaagttgg gagcctgaaa tagtggttct   3060

tggaaaaatg gatccccagt gaaaactaga gctctaagcc cattcagccc atttcacacc   3120

tgaaaatgtt agtgatcacc acttggacca gcatccttaa gtatcagaaa gccccaagca   3180

attgctgcat cttagtaggg tgagggataa gcaaaagagg atgttcacca taacccagga   3240

atgaagatac catcagcaaa gaatttcaat ttgttcagtc tttcatttag agctagtctt   3300

tcacagtacc atctgaatac ctctttgaaa gaaggaagac tttacgtagt gtagatttgt   3360

tttgtgttgt ttgaaaatat tatctttgta attattttta atatgtaagg aatgcttgga   3420

atatctgctg tatgtcaact ttatgcagct tccttttgag ggacaaattt aaaacaaaca   3480

accccccatc acaaacttaa aggattgcaa gggccagatc tgttaagtgg tttcatagga   3540

gacacatcca gcaattgtgt ggtcagtggc tcttttaccc aataagatac atcacagtca   3600

catgcttgat ggtttatgtt gacctaagat ttattttgtt aaaatctctc tctgttgtgt   3660

tcgttcttgt tctgttttgt tttgtttttt aaagtcttgc tgtggtctct ttgtggcaga   3720

agtgtttcat gcatggcagc aggcctgttg cttttttatg gcgattccca ttgaaaatgt   3780

aagtaaatgt ctgtggcctt gttctctcta tggtaaagat attattcacc atgtaaaaca   3840

aaaaacaata tttattgtat tttagtatat ttatataatt atgttattga aaaaaattgg   3900

cattaaaact taaccgcatc agaagcctat tgtaaataca agttctattt aagtgtacta   3960

attaacatat aatatatgtt ttaaatatag aatttttaat gtttttaaat atattttcaa   4020

agtacat                                                             4027


<210>  7863
<211>  255
<212>  PRT
<213>  Homo sapiens

<400>  7863

Met Phe His Gln Val Arg Arg Val Met Thr Ile Leu Phe Leu Thr Met 
1               5                   10                  15


Val Ile Ser Tyr Phe Gly Cys Met Lys Ala Ala Pro Met Lys Glu Ala 
            20                  25                  30


Asn Ile Arg Gly Gln Gly Gly Leu Ala Tyr Pro Gly Val Arg Thr His 
        35                  40                  45


Gly Thr Leu Glu Ser Val Asn Gly Pro Lys Ala Gly Ser Arg Gly Leu 
    50                  55                  60


Thr Ser Leu Ala Asp Thr Phe Glu His Val Ile Glu Glu Leu Leu Asp 
65                  70                  75                  80


Glu Asp Gln Lys Val Arg Pro Asn Glu Glu Asn Asn Lys Asp Ala Asp 
                85                  90                  95


Leu Tyr Thr Ser Arg Val Met Leu Ser Ser Gln Val Pro Leu Glu Pro 
            100                 105                 110


Pro Leu Leu Phe Leu Leu Glu Glu Tyr Lys Asn Tyr Leu Asp Ala Ala 
        115                 120                 125


Asn Met Ser Met Arg Val Arg Arg His Ser Asp Pro Ala Arg Arg Gly 
    130                 135                 140


Glu Leu Ser Val Cys Asp Ser Ile Ser Glu Trp Val Thr Ala Ala Asp 
145                 150                 155                 160


Lys Lys Thr Ala Val Asp Met Ser Gly Gly Thr Val Thr Val Leu Glu 
                165                 170                 175


Lys Val Pro Val Ser Lys Gly Gln Leu Lys Gln Tyr Phe Tyr Glu Thr 
            180                 185                 190


Lys Cys Asn Pro Met Gly Tyr Thr Lys Glu Gly Cys Arg Gly Ile Asp 
        195                 200                 205


Lys Arg His Trp Asn Ser Gln Cys Arg Thr Thr Gln Ser Tyr Val Arg 
    210                 215                 220


Ala Leu Thr Met Asp Ser Lys Lys Arg Ile Gly Trp Arg Phe Ile Arg 
225                 230                 235                 240


Ile Asp Thr Ser Cys Val Cys Thr Leu Thr Ile Lys Arg Gly Arg 
                245                 250                 255


<210>  7864
<211>  3659
<212>  DNA
<213>  Homo sapiens

<400>  7864
agtggactta caagtccgaa gccaatgtag cttggaaaac ttgggaggcg gaattcctac     60

cgctgggaac tgaaagggtc tgcgacactc tcgggcaggc cgaacccaca tctctaccca    120

tcctgcgccc ctcttctgaa gcgccctcca gttccaccag gtgagaagag tgatgaccat    180

ccttttcctt actatggtta tttcatactt tggttgcatg aaggctgccc ccatgaaaga    240

agcaaacatc cgaggacaag gtggcttggc ctacccaggt gtgcggaccc atgggactct    300

ggagagcgtg aatgggccca aggcaggttc aagaggcttg acatcattgg ctgacacttt    360

cgaacacgtg atagaagagc tgttggatga ggaccagaaa gttcggccca atgaagaaaa    420

caataaggac gcagacttgt acacgtccag ggtgatgctc agtagtcaag tgcctttgga    480

gcctcctctt ctctttctgc tggaggaata caaaaattac ctagatgctg caaacatgtc    540

catgagggtc cggcgccact ctgaccctgc ccgccgaggg gagctgagcg tgtgtgacag    600

tattagtgag tgggtaacgg cagcagacaa aaagactgca gtggacatgt cgggcgggac    660

ggtcacagtc cttgaaaagg tccctgtatc aaaaggccaa ctgaagcaat acttctacga    720

gaccaagtgc aatcccatgg gttacacaaa agaaggctgc aggggcatag acaaaaggca    780

ttggaactcc cagtgccgaa ctacccagtc gtacgtgcgg gcccttacca tggatagcaa    840

aaagagaatt ggctggcgat tcataaggat agacacttct tgtgtatgta cattgaccat    900

taaaagggga agatagtgga tttatgttgt atagattaga ttatattgag acaaaaatta    960

tctatttgta tatatacata acagggtaaa ttattcagtt aagaaaaaaa taattttatg   1020

aactgcatgt ataaatgaag tttatacagt acagtggttc tacaatctat ttattggaca   1080

tgtccatgac cagaagggaa acagtcattt gcgcacaact taaaaagtct gcattacatt   1140

ccttgataat gttgtggttt gttgccgttg ccaagaactg aaaacataaa aagttaaaaa   1200

aaataataaa ttgcatgctg ctttaattgt gaattgataa taaactgtcc tctttcagaa   1260

aacagaaaaa aaacacacac acacacaaca aaaatttgaa ccaaaacatt ccgtttacat   1320

tttagacagt aagtatcttc gttcttgtta gtactatatc tgttttactg cttttaactt   1380

ctgatagcgt tggaattaaa acaatgtcaa ggtgctgttg tcattgcttt actggcttag   1440

gggatggggg atggggggta tatttttgtt tgttttgtgt ttttttttcg tttgtttgtt   1500

ttgtttttta gttcccacag ggagtagaga tggggaaaga attcctacaa tatatattct   1560

ggctgataaa agatacattt gtatgttgtg aagatgtttg caatatcgat cagatgacta   1620

gaaagtgaat aaaaattaag gcaactgaac aaaaaaatgc tcacactcca catcccgtga   1680

tgcacctccc aggccccgct cattctttgg gcgttggtca gagtaagctg cttttgacgg   1740

aaggacctat gtttgctcag aacacattct ttccccccct ccccctctgg tctcctcttt   1800

gttttgtttt aaggaagaaa aatcagttgc gcgttctgaa atattttacc actgctgtga   1860

acaagtgaac acattgtgtc acatcatgac actcgtataa gcatggagaa cagtgatttt   1920

tttttagaac agaaaacaac aaaaaataac cccaaaatga agattatttt ttatgaggag   1980

tgaacatttg ggtaaatcat ggctaagctt aaaaaaaact catggtgagg cttaacaatg   2040

tcttgtaagc aaaaggtaga gccctgtatc aacccagaaa cacctagatc agaacaggaa   2100

tccacattgc cagtgacatg agactgaaca gccaaatgga ggctatgtgg agttggcatt   2160

gcatttaccg gcagtgcggg aggaatttct gagtggccat cccaaggtct aggtggaggt   2220

ggggcatggt atttgagaca ttccaaaacg aaggcctctg aaggaccctt cagaggtggc   2280

tctggaatga catgtgtcaa gctgcttgga cctcgtgctt taagtgccta cattatctaa   2340

ctgtgctcaa gaggttctcg actggaggac cacactcaag ccgacttatg cccaccatcc   2400

cacctctgga taattttgca taaaattgga ttagcctgga gcaggttggg agccaaatgt   2460

ggcatttgtg atcatgagat tgatgcaatg agatagaaga tgtttgctac ctgaacactt   2520

attgctttga aactagactt gaggaaacca gggtttatct tttgagaact tttggtaagg   2580

gaaaagggaa caggaaaaga aaccccaaac tcaggccgaa tgatcaaggg gacccatagg   2640

aaatcttgtc cagagacaag acttcgggaa ggtgtctgga cattcagaac accaagactt   2700

gaaggtgcct tgctcaatgg aagaggccag gacagagctg acaaaatttt gctccccagt   2760

gaaggccaca gcaaccttct gcccatcctg tctgttcatg gagagggtcc ctgcctcacc   2820

tctgccattt tgggttagga gaagtcaagt tgggagcctg aaatagtggt tcttggaaaa   2880

atggatcccc agtgaaaact agagctctaa gcccattcag cccatttcac acctgaaaat   2940

gttagtgatc accacttgga ccagcatcct taagtatcag aaagccccaa gcaattgctg   3000

catcttagta gggtgaggga taagcaaaag aggatgttca ccataaccca ggaatgaaga   3060

taccatcagc aaagaatttc aatttgttca gtctttcatt tagagctagt ctttcacagt   3120

accatctgaa tacctctttg aaagaaggaa gactttacgt agtgtagatt tgttttgtgt   3180

tgtttgaaaa tattatcttt gtaattattt ttaatatgta aggaatgctt ggaatatctg   3240

ctgtatgtca actttatgca gcttcctttt gagggacaaa tttaaaacaa acaacccccc   3300

atcacaaact taaaggattg caagggccag atctgttaag tggtttcata ggagacacat   3360

ccagcaattg tgtggtcagt ggctctttta cccaataaga tacatcacag tcacatgctt   3420

gatggtttat gttgacctaa gatttatttt gttaaaatct ctctctgttg tgttcgttct   3480

tgttctgttt tgttttgttt tttaaagtct tgctgtggtc tctttgtggc agaagtgttt   3540

catgcatggc agcaggcctg ttgctttttt atggcgattc ccattgaaaa tgtaagtaaa   3600

tgtctgtggc cttgttctct ctatggtaaa gatattattc accatgtaaa acaaaaaac    3659


<210>  7865
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7865

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7866
<211>  1516
<212>  DNA
<213>  Homo sapiens

<400>  7866
agtggactta caagtccgaa gccaatgtag cttggaaaac ttgggaggcg gaattcctac     60

cgctgggaac tgaaagggtc tgcgacactc tcgggcaggc cgaacccaca tctctaccca    120

tcctgcgccc ctcttctgaa gcgccctcca gggaagttaa gagttttgac tttcggggag    180

tggttgggat gtacgtgggg gattcttgac tcgggttagt ctctggggat gcagagccgg    240

gaagaggaat ggttccacca ggtgagaaga gtgatgacca tccttttcct tactatggtt    300

atttcatact ttggttgcat gaaggctgcc cccatgaaag aagcaaacat ccgaggacaa    360

ggtggcttgg cctacccagg tgtgcggacc catgggactc tggagagcgt gaatgggccc    420

aaggcaggtt caagaggctt gacatcattg gctgacactt tcgaacacgt gatagaagag    480

ctgttggatg aggaccagaa agttcggccc aatgaagaaa acaataagga cgcagacttg    540

tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg agcctcctct tctctttctg    600

ctggaggaat acaaaaatta cctagatgct gcaaacatgt ccatgagggt ccggcgccac    660

tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca gtattagtga gtgggtaacg    720

gcagcagaca aaaagactgc agtggacatg tcgggcggga cggtcacagt ccttgaaaag    780

gtccctgtat caaaaggcca actgaagcaa tacttctacg agaccaagtg caatcccatg    840

ggttacacaa aagaaggctg caggggcata gacaaaaggc attggaactc ccagtgccga    900

actacccagt cgtacgtgcg ggcccttacc atggatagca aaaagagaat tggctggcga    960

ttcataagga tagacacttc ttgtgtatgt acattgacca ttaaaagggg aagatagtgg   1020

atttatgttg tatagattag attatattga gacaaaaatt atctatttgt atatatacat   1080

aacagggtaa attattcagt taagaaaaaa ataattttat gaactgcatg tataaatgaa   1140

gtttatacag tacagtggtt ctacaatcta tttattggac atgtccatga ccagaaggga   1200

aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat tccttgataa tgttgtggtt   1260

tgttgccgtt gccaagaact gaaaacataa aaagttaaaa aaaataataa attgcatgct   1320

gctttaattg tgaattgata ataaactgtc ctctttcaga aaacagaaaa aaaacacaca   1380

cacacacaac aaaaatttga accaaaacat tccgtttaca ttttagacag taagtatctt   1440

cgttcttgtt agtactatat ctgttttact gcttttaact tctgatagcg ttggaattaa   1500

aacaatgtca aggtgc                                                   1516


<210>  7867
<211>  262
<212>  PRT
<213>  Homo sapiens

<400>  7867

Met Gln Ser Arg Glu Glu Glu Trp Phe His Gln Val Arg Arg Val Met 
1               5                   10                  15


Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met Lys 
            20                  25                  30


Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu Ala 
        35                  40                  45


Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly Pro 
    50                  55                  60


Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu His 
65                  70                  75                  80


Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn Glu 
                85                  90                  95


Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu Ser 
            100                 105                 110


Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu Tyr 
        115                 120                 125


Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg His 
    130                 135                 140


Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile Ser 
145                 150                 155                 160


Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser Gly 
                165                 170                 175


Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln Leu 
            180                 185                 190


Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr Lys 
        195                 200                 205


Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys Arg 
    210                 215                 220


Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys Arg 
225                 230                 235                 240


Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr Leu 
                245                 250                 255


Thr Ile Lys Arg Gly Arg 
            260


<210>  7868
<211>  1546
<212>  DNA
<213>  Homo sapiens

<400>  7868
gctccgggtc cccgacgctg ccgccgccgc gcccgggcgc acccgcccgc tcgctgtccc     60

gcgcaccccg tagcgcctcg ggctcccggg ccggacagag gagccagccc ggtgcgcccc    120

tccacctcct gctcgggggg ctttaatgag acacccaccg ctgctgtggg gccggcgggg    180

agcagcaccg cgacggggac cggggctggg cgctggagcc agaatcggaa ccacgatgtg    240

actccgccgc cggggacccg tgaggtttgt gtggaccccg agttccacca ggtgagaaga    300

gtgatgacca tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc    360

cccatgaaag aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc    420

catgggactc tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg    480

gctgacactt tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc    540

aatgaagaaa acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa    600

gtgcctttgg agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct    660

gcaaacatgt ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc    720

gtgtgtgaca gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg    780

tcgggcggga cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa    840

tacttctacg agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata    900

gacaaaaggc attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc    960

atggatagca aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt   1020

acattgacca ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga   1080

gacaaaaatt atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa   1140

ataattttat gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta   1200

tttattggac atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc   1260

tgcattacat tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa   1320

aaagttaaaa aaaataataa attgcatgct gctttaattg tgaattgata ataaactgtc   1380

ctctttcaga aaacagaaaa aaaacacaca cacacacaac aaaaatttga accaaaacat   1440

tccgtttaca ttttagacag taagtatctt cgttcttgtt agtactatat ctgttttact   1500

gcttttaact tctgatagcg ttggaattaa aacaatgtca aggtgc                  1546


<210>  7869
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7869

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7870
<211>  1468
<212>  DNA
<213>  Homo sapiens

<400>  7870
gagacctcgg ggcgtgcgat tctcactcgc tccctcccgc cccagcgccc acagccgggg     60

tttctgcaga gggcgcggga cgcggggttc cccggggctg aggctggggc tggaacaccc    120

ctcgaagccg cgggcgtcct gtccaaggcg ccccaggagg gcgcaggact cgcagggcga    180

tgtcgcgggg ccctagggga ggagttccac caggtgagaa gagtgatgac catccttttc    240

cttactatgg ttatttcata ctttggttgc atgaaggctg cccccatgaa agaagcaaac    300

atccgaggac aaggtggctt ggcctaccca ggtgtgcgga cccatgggac tctggagagc    360

gtgaatgggc ccaaggcagg ttcaagaggc ttgacatcat tggctgacac tttcgaacac    420

gtgatagaag agctgttgga tgaggaccag aaagttcggc ccaatgaaga aaacaataag    480

gacgcagact tgtacacgtc cagggtgatg ctcagtagtc aagtgccttt ggagcctcct    540

cttctctttc tgctggagga atacaaaaat tacctagatg ctgcaaacat gtccatgagg    600

gtccggcgcc actctgaccc tgcccgccga ggggagctga gcgtgtgtga cagtattagt    660

gagtgggtaa cggcagcaga caaaaagact gcagtggaca tgtcgggcgg gacggtcaca    720

gtccttgaaa aggtccctgt atcaaaaggc caactgaagc aatacttcta cgagaccaag    780

tgcaatccca tgggttacac aaaagaaggc tgcaggggca tagacaaaag gcattggaac    840

tcccagtgcc gaactaccca gtcgtacgtg cgggccctta ccatggatag caaaaagaga    900

attggctggc gattcataag gatagacact tcttgtgtat gtacattgac cattaaaagg    960

ggaagatagt ggatttatgt tgtatagatt agattatatt gagacaaaaa ttatctattt   1020

gtatatatac ataacagggt aaattattca gttaagaaaa aaataatttt atgaactgca   1080

tgtataaatg aagtttatac agtacagtgg ttctacaatc tatttattgg acatgtccat   1140

gaccagaagg gaaacagtca tttgcgcaca acttaaaaag tctgcattac attccttgat   1200

aatgttgtgg tttgttgccg ttgccaagaa ctgaaaacat aaaaagttaa aaaaaataat   1260

aaattgcatg ctgctttaat tgtgaattga taataaactg tcctctttca gaaaacagaa   1320

aaaaaacaca cacacacaca acaaaaattt gaaccaaaac attccgttta cattttagac   1380

agtaagtatc ttcgttcttg ttagtactat atctgtttta ctgcttttaa cttctgatag   1440

cgttggaatt aaaacaatgt caaggtgc                                      1468


<210>  7871
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  7871

Met Ser Arg Gly Pro Arg Gly Gly Val Pro Pro Gly Glu Lys Ser Asp 
1               5                   10                  15


Asp His Pro Phe Pro Tyr Tyr Gly Tyr Phe Ile Leu Trp Leu His Glu 
            20                  25                  30


Gly Cys Pro His Glu Arg Ser Lys His Pro Arg Thr Arg Trp Leu Gly 
        35                  40                  45


Leu Pro Arg Cys Ala Asp Pro Trp Asp Ser Gly Glu Arg Glu Trp Ala 
    50                  55                  60


Gln Gly Arg Phe Lys Arg Leu Asp Ile Ile Gly 
65                  70                  75


<210>  7872
<211>  1596
<212>  DNA
<213>  Homo sapiens

<400>  7872
ctttcccatt caccgcggag agggctgctc tcgctgccgc tccccccggc gaactagcat     60

gaaatctccc tgcctctgcc gagatcaaat ggagcttctc gctgatgggg tgcgagtatt    120

acctccgcca tgcaatttcc actatcaata atttaacttc tttgctgcag aacagaagga    180

gtacataccg ggcaccaaag actcgcgccc cctcccccct ttaattaagc gaagggaacg    240

tgaaaaaata atagagtgtg ggagttttgg ggccgaagtc tttcccggag cagctgcctt    300

gatggttact ttgacaagta gtgactgaaa agttccacca ggtgagaaga gtgatgacca    360

tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc cccatgaaag    420

aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc catgggactc    480

tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg gctgacactt    540

tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc aatgaagaaa    600

acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg    660

agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct gcaaacatgt    720

ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca    780

gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg tcgggcggga    840

cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa tacttctacg    900

agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata gacaaaaggc    960

attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc atggatagca   1020

aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt acattgacca   1080

ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga gacaaaaatt   1140

atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa ataattttat   1200

gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta tttattggac   1260

atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat   1320

tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa aaagttaaaa   1380

aaaataataa attgcatgct gctttaattg tgaattgata ataaactgtc ctctttcaga   1440

aaacagaaaa aaaacacaca cacacacaac aaaaatttga accaaaacat tccgtttaca   1500

ttttagacag taagtatctt cgttcttgtt agtactatat ctgttttact gcttttaact   1560

tctgatagcg ttggaattaa aacaatgtca aggtgc                             1596


<210>  7873
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7873

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7874
<211>  1597
<212>  DNA
<213>  Homo sapiens

<400>  7874
gccaacggat ttgtccgagg tggcggtacc cccaggtagt cttcttggcc ccgctgtaaa     60

gccaaccctg tgtcgccctt aaaaagcgtc ttttctgagg ttcggctcac actgagatcg    120

gggctggaga gagagtcaga ttttggagcg gagcgtttgg aaagcgagcc ccagtttggt    180

cccctcattg agctcgctga agttggcttc ctagcggtgt aggctggaat agactcttgg    240

caagctccgg gttggtatac tgggttaact ttgggaaatg caagtgttta tctccaggat    300

ctagccaccg gggtggtgta agccgcaaag aagttccacc aggtgagaag agtgatgacc    360

atccttttcc ttactatggt tatttcatac tttggttgca tgaaggctgc ccccatgaaa    420

gaagcaaaca tccgaggaca aggtggcttg gcctacccag gtgtgcggac ccatgggact    480

ctggagagcg tgaatgggcc caaggcaggt tcaagaggct tgacatcatt ggctgacact    540

ttcgaacacg tgatagaaga gctgttggat gaggaccaga aagttcggcc caatgaagaa    600

aacaataagg acgcagactt gtacacgtcc agggtgatgc tcagtagtca agtgcctttg    660

gagcctcctc ttctctttct gctggaggaa tacaaaaatt acctagatgc tgcaaacatg    720

tccatgaggg tccggcgcca ctctgaccct gcccgccgag gggagctgag cgtgtgtgac    780

agtattagtg agtgggtaac ggcagcagac aaaaagactg cagtggacat gtcgggcggg    840

acggtcacag tccttgaaaa ggtccctgta tcaaaaggcc aactgaagca atacttctac    900

gagaccaagt gcaatcccat gggttacaca aaagaaggct gcaggggcat agacaaaagg    960

cattggaact cccagtgccg aactacccag tcgtacgtgc gggcccttac catggatagc   1020

aaaaagagaa ttggctggcg attcataagg atagacactt cttgtgtatg tacattgacc   1080

attaaaaggg gaagatagtg gatttatgtt gtatagatta gattatattg agacaaaaat   1140

tatctatttg tatatataca taacagggta aattattcag ttaagaaaaa aataatttta   1200

tgaactgcat gtataaatga agtttataca gtacagtggt tctacaatct atttattgga   1260

catgtccatg accagaaggg aaacagtcat ttgcgcacaa cttaaaaagt ctgcattaca   1320

ttccttgata atgttgtggt ttgttgccgt tgccaagaac tgaaaacata aaaagttaaa   1380

aaaaataata aattgcatgc tgctttaatt gtgaattgat aataaactgt cctctttcag   1440

aaaacagaaa aaaaacacac acacacacaa caaaaatttg aaccaaaaca ttccgtttac   1500

attttagaca gtaagtatct tcgttcttgt tagtactata tctgttttac tgcttttaac   1560

ttctgatagc gttggaatta aaacaatgtc aaggtgc                            1597


<210>  7875
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7875

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7876
<211>  1581
<212>  DNA
<213>  Homo sapiens

<400>  7876
tcattcatta gaatcacgta agaactcaaa aggaaacgtg tctctcggag tgagggcgtt     60

tgcgtaaatc tataggtttt tcgacatcga tgccagttgc tttgtcttct gtagtcgcca    120

aggtggttga gagtttaagc ttgcggatat tgcaaagggt tattagattc ataagtcaca    180

ccaagtggtg ggcgatccac tgagcaaagc cgaacttctc acatgatgac ttcaaacaag    240

acacattacc ttccagcatc tgttggggag acgagatttt aagacacttg agtctccagg    300

acagcaaagg cacaatgttc caccaggtga gaagagtgat gaccatcctt ttccttacta    360

tggttatttc atactttggt tgcatgaagg ctgcccccat gaaagaagca aacatccgag    420

gacaaggtgg cttggcctac ccaggtgtgc ggacccatgg gactctggag agcgtgaatg    480

ggcccaaggc aggttcaaga ggcttgacat cattggctga cactttcgaa cacgtgatag    540

aagagctgtt ggatgaggac cagaaagttc ggcccaatga agaaaacaat aaggacgcag    600

acttgtacac gtccagggtg atgctcagta gtcaagtgcc tttggagcct cctcttctct    660

ttctgctgga ggaatacaaa aattacctag atgctgcaaa catgtccatg agggtccggc    720

gccactctga ccctgcccgc cgaggggagc tgagcgtgtg tgacagtatt agtgagtggg    780

taacggcagc agacaaaaag actgcagtgg acatgtcggg cgggacggtc acagtccttg    840

aaaaggtccc tgtatcaaaa ggccaactga agcaatactt ctacgagacc aagtgcaatc    900

ccatgggtta cacaaaagaa ggctgcaggg gcatagacaa aaggcattgg aactcccagt    960

gccgaactac ccagtcgtac gtgcgggccc ttaccatgga tagcaaaaag agaattggct   1020

ggcgattcat aaggatagac acttcttgtg tatgtacatt gaccattaaa aggggaagat   1080

agtggattta tgttgtatag attagattat attgagacaa aaattatcta tttgtatata   1140

tacataacag ggtaaattat tcagttaaga aaaaaataat tttatgaact gcatgtataa   1200

atgaagttta tacagtacag tggttctaca atctatttat tggacatgtc catgaccaga   1260

agggaaacag tcatttgcgc acaacttaaa aagtctgcat tacattcctt gataatgttg   1320

tggtttgttg ccgttgccaa gaactgaaaa cataaaaagt taaaaaaaat aataaattgc   1380

atgctgcttt aattgtgaat tgataataaa ctgtcctctt tcagaaaaca gaaaaaaaac   1440

acacacacac acaacaaaaa tttgaaccaa aacattccgt ttacatttta gacagtaagt   1500

atcttcgttc ttgttagtac tatatctgtt ttactgcttt taacttctga tagcgttgga   1560

attaaaacaa tgtcaaggtg c                                             1581


<210>  7877
<211>  255
<212>  PRT
<213>  Homo sapiens

<400>  7877

Met Phe His Gln Val Arg Arg Val Met Thr Ile Leu Phe Leu Thr Met 
1               5                   10                  15


Val Ile Ser Tyr Phe Gly Cys Met Lys Ala Ala Pro Met Lys Glu Ala 
            20                  25                  30


Asn Ile Arg Gly Gln Gly Gly Leu Ala Tyr Pro Gly Val Arg Thr His 
        35                  40                  45


Gly Thr Leu Glu Ser Val Asn Gly Pro Lys Ala Gly Ser Arg Gly Leu 
    50                  55                  60


Thr Ser Leu Ala Asp Thr Phe Glu His Val Ile Glu Glu Leu Leu Asp 
65                  70                  75                  80


Glu Asp Gln Lys Val Arg Pro Asn Glu Glu Asn Asn Lys Asp Ala Asp 
                85                  90                  95


Leu Tyr Thr Ser Arg Val Met Leu Ser Ser Gln Val Pro Leu Glu Pro 
            100                 105                 110


Pro Leu Leu Phe Leu Leu Glu Glu Tyr Lys Asn Tyr Leu Asp Ala Ala 
        115                 120                 125


Asn Met Ser Met Arg Val Arg Arg His Ser Asp Pro Ala Arg Arg Gly 
    130                 135                 140


Glu Leu Ser Val Cys Asp Ser Ile Ser Glu Trp Val Thr Ala Ala Asp 
145                 150                 155                 160


Lys Lys Thr Ala Val Asp Met Ser Gly Gly Thr Val Thr Val Leu Glu 
                165                 170                 175


Lys Val Pro Val Ser Lys Gly Gln Leu Lys Gln Tyr Phe Tyr Glu Thr 
            180                 185                 190


Lys Cys Asn Pro Met Gly Tyr Thr Lys Glu Gly Cys Arg Gly Ile Asp 
        195                 200                 205


Lys Arg His Trp Asn Ser Gln Cys Arg Thr Thr Gln Ser Tyr Val Arg 
    210                 215                 220


Ala Leu Thr Met Asp Ser Lys Lys Arg Ile Gly Trp Arg Phe Ile Arg 
225                 230                 235                 240


Ile Asp Thr Ser Cys Val Cys Thr Leu Thr Ile Lys Arg Gly Arg 
                245                 250                 255


<210>  7878
<211>  1325
<212>  DNA
<213>  Homo sapiens

<400>  7878
agtggactta caagtccgaa gccaatgtag cttggaaaac ttgggaggcg gaattcctac     60

cgctgggaac tgaaagggtc tgcgacactc tcgggcaggc cgaacccaca tctctaccca    120

tcctgcgccc ctcttctgaa gcgccctcca gggaagttaa gagttttgac tttcggggag    180

tggttgggat gtacgtgggg gattcttgac tcgggttagt ctctggggat gcagagccgg    240

gaagaggaat ggttccacca ggtgagaaga gtgatgacca tccttttcct tactatggtt    300

atttcatact ttggttgcat gaaggctgcc cccatgaaag aagcaaacat ccgaggacaa    360

ggtggcttgg cctacccagg tgtgcggacc catgggactc tggagagcgt gaatgggccc    420

aaggcaggtt caagaggctt gacatcattg gctgacactt tcgaacacgt gatagaagag    480

ctgttggatg aggaccagaa agttcggccc aatgaagaaa acaataagga cgcagacttg    540

tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg agcctcctct tctctttctg    600

ctggaggaat acaaaaatta cctagatgct gcaaacatgt ccatgagggt ccggcgccac    660

tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca gtattagtga gtgggtaacg    720

gcagcagaca aaaagactgc agtggacatg tcgggcggga cggtcacagt ccttgaaaag    780

gtccctgtat caaaaggcca actgaagcaa tacttctacg agaccaagtg caatcccatg    840

ggttacacaa aagaaggctg caggggcata gacaaaaggc attggaactc ccagtgccga    900

actacccagt cgtacgtgcg ggcccttacc atggatagca aaaagagaat tggctggcga    960

ttcataagga tagacacttc ttgtgtatgt acattgacca ttaaaagggg aagatagtgg   1020

atttatgttg tatagattag attatattga gacaaaaatt atctatttgt atatatacat   1080

aacagggtaa attattcagt taagaaaaaa ataattttat gaactgcatg tataaatgaa   1140

gtttatacag tacagtggtt ctacaatcta tttattggac atgtccatga ccagaaggga   1200

aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat tccttgataa tgttgtggtt   1260

tgttgccgtt gccaagaact gaaaacataa aaagttaaaa aaaataataa attgcatgct   1320

gcttt                                                               1325


<210>  7879
<211>  262
<212>  PRT
<213>  Homo sapiens

<400>  7879

Met Gln Ser Arg Glu Glu Glu Trp Phe His Gln Val Arg Arg Val Met 
1               5                   10                  15


Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met Lys 
            20                  25                  30


Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu Ala 
        35                  40                  45


Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly Pro 
    50                  55                  60


Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu His 
65                  70                  75                  80


Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn Glu 
                85                  90                  95


Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu Ser 
            100                 105                 110


Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu Tyr 
        115                 120                 125


Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg His 
    130                 135                 140


Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile Ser 
145                 150                 155                 160


Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser Gly 
                165                 170                 175


Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln Leu 
            180                 185                 190


Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr Lys 
        195                 200                 205


Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys Arg 
    210                 215                 220


Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys Arg 
225                 230                 235                 240


Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr Leu 
                245                 250                 255


Thr Ile Lys Arg Gly Arg 
            260


<210>  7880
<211>  1355
<212>  DNA
<213>  Homo sapiens

<400>  7880
gctccgggtc cccgacgctg ccgccgccgc gcccgggcgc acccgcccgc tcgctgtccc     60

gcgcaccccg tagcgcctcg ggctcccggg ccggacagag gagccagccc ggtgcgcccc    120

tccacctcct gctcgggggg ctttaatgag acacccaccg ctgctgtggg gccggcgggg    180

agcagcaccg cgacggggac cggggctggg cgctggagcc agaatcggaa ccacgatgtg    240

actccgccgc cggggacccg tgaggtttgt gtggaccccg agttccacca ggtgagaaga    300

gtgatgacca tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc    360

cccatgaaag aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc    420

catgggactc tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg    480

gctgacactt tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc    540

aatgaagaaa acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa    600

gtgcctttgg agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct    660

gcaaacatgt ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc    720

gtgtgtgaca gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg    780

tcgggcggga cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa    840

tacttctacg agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata    900

gacaaaaggc attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc    960

atggatagca aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt   1020

acattgacca ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga   1080

gacaaaaatt atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa   1140

ataattttat gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta   1200

tttattggac atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc   1260

tgcattacat tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa   1320

aaagttaaaa aaaataataa attgcatgct gcttt                              1355


<210>  7881
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7881

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7882
<211>  1277
<212>  DNA
<213>  Homo sapiens

<400>  7882
gagacctcgg ggcgtgcgat tctcactcgc tccctcccgc cccagcgccc acagccgggg     60

tttctgcaga gggcgcggga cgcggggttc cccggggctg aggctggggc tggaacaccc    120

ctcgaagccg cgggcgtcct gtccaaggcg ccccaggagg gcgcaggact cgcagggcga    180

tgtcgcgggg ccctagggga ggagttccac caggtgagaa gagtgatgac catccttttc    240

cttactatgg ttatttcata ctttggttgc atgaaggctg cccccatgaa agaagcaaac    300

atccgaggac aaggtggctt ggcctaccca ggtgtgcgga cccatgggac tctggagagc    360

gtgaatgggc ccaaggcagg ttcaagaggc ttgacatcat tggctgacac tttcgaacac    420

gtgatagaag agctgttgga tgaggaccag aaagttcggc ccaatgaaga aaacaataag    480

gacgcagact tgtacacgtc cagggtgatg ctcagtagtc aagtgccttt ggagcctcct    540

cttctctttc tgctggagga atacaaaaat tacctagatg ctgcaaacat gtccatgagg    600

gtccggcgcc actctgaccc tgcccgccga ggggagctga gcgtgtgtga cagtattagt    660

gagtgggtaa cggcagcaga caaaaagact gcagtggaca tgtcgggcgg gacggtcaca    720

gtccttgaaa aggtccctgt atcaaaaggc caactgaagc aatacttcta cgagaccaag    780

tgcaatccca tgggttacac aaaagaaggc tgcaggggca tagacaaaag gcattggaac    840

tcccagtgcc gaactaccca gtcgtacgtg cgggccctta ccatggatag caaaaagaga    900

attggctggc gattcataag gatagacact tcttgtgtat gtacattgac cattaaaagg    960

ggaagatagt ggatttatgt tgtatagatt agattatatt gagacaaaaa ttatctattt   1020

gtatatatac ataacagggt aaattattca gttaagaaaa aaataatttt atgaactgca   1080

tgtataaatg aagtttatac agtacagtgg ttctacaatc tatttattgg acatgtccat   1140

gaccagaagg gaaacagtca tttgcgcaca acttaaaaag tctgcattac attccttgat   1200

aatgttgtgg tttgttgccg ttgccaagaa ctgaaaacat aaaaagttaa aaaaaataat   1260

aaattgcatg ctgcttt                                                  1277


<210>  7883
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  7883

Met Ser Arg Gly Pro Arg Gly Gly Val Pro Pro Gly Glu Lys Ser Asp 
1               5                   10                  15


Asp His Pro Phe Pro Tyr Tyr Gly Tyr Phe Ile Leu Trp Leu His Glu 
            20                  25                  30


Gly Cys Pro His Glu Arg Ser Lys His Pro Arg Thr Arg Trp Leu Gly 
        35                  40                  45


Leu Pro Arg Cys Ala Asp Pro Trp Asp Ser Gly Glu Arg Glu Trp Ala 
    50                  55                  60


Gln Gly Arg Phe Lys Arg Leu Asp Ile Ile Gly 
65                  70                  75


<210>  7884
<211>  1405
<212>  DNA
<213>  Homo sapiens

<400>  7884
ctttcccatt caccgcggag agggctgctc tcgctgccgc tccccccggc gaactagcat     60

gaaatctccc tgcctctgcc gagatcaaat ggagcttctc gctgatgggg tgcgagtatt    120

acctccgcca tgcaatttcc actatcaata atttaacttc tttgctgcag aacagaagga    180

gtacataccg ggcaccaaag actcgcgccc cctcccccct ttaattaagc gaagggaacg    240

tgaaaaaata atagagtgtg ggagttttgg ggccgaagtc tttcccggag cagctgcctt    300

gatggttact ttgacaagta gtgactgaaa agttccacca ggtgagaaga gtgatgacca    360

tccttttcct tactatggtt atttcatact ttggttgcat gaaggctgcc cccatgaaag    420

aagcaaacat ccgaggacaa ggtggcttgg cctacccagg tgtgcggacc catgggactc    480

tggagagcgt gaatgggccc aaggcaggtt caagaggctt gacatcattg gctgacactt    540

tcgaacacgt gatagaagag ctgttggatg aggaccagaa agttcggccc aatgaagaaa    600

acaataagga cgcagacttg tacacgtcca gggtgatgct cagtagtcaa gtgcctttgg    660

agcctcctct tctctttctg ctggaggaat acaaaaatta cctagatgct gcaaacatgt    720

ccatgagggt ccggcgccac tctgaccctg cccgccgagg ggagctgagc gtgtgtgaca    780

gtattagtga gtgggtaacg gcagcagaca aaaagactgc agtggacatg tcgggcggga    840

cggtcacagt ccttgaaaag gtccctgtat caaaaggcca actgaagcaa tacttctacg    900

agaccaagtg caatcccatg ggttacacaa aagaaggctg caggggcata gacaaaaggc    960

attggaactc ccagtgccga actacccagt cgtacgtgcg ggcccttacc atggatagca   1020

aaaagagaat tggctggcga ttcataagga tagacacttc ttgtgtatgt acattgacca   1080

ttaaaagggg aagatagtgg atttatgttg tatagattag attatattga gacaaaaatt   1140

atctatttgt atatatacat aacagggtaa attattcagt taagaaaaaa ataattttat   1200

gaactgcatg tataaatgaa gtttatacag tacagtggtt ctacaatcta tttattggac   1260

atgtccatga ccagaaggga aacagtcatt tgcgcacaac ttaaaaagtc tgcattacat   1320

tccttgataa tgttgtggtt tgttgccgtt gccaagaact gaaaacataa aaagttaaaa   1380

aaaataataa attgcatgct gcttt                                         1405


<210>  7885
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7885

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7886
<211>  1406
<212>  DNA
<213>  Homo sapiens

<400>  7886
gccaacggat ttgtccgagg tggcggtacc cccaggtagt cttcttggcc ccgctgtaaa     60

gccaaccctg tgtcgccctt aaaaagcgtc ttttctgagg ttcggctcac actgagatcg    120

gggctggaga gagagtcaga ttttggagcg gagcgtttgg aaagcgagcc ccagtttggt    180

cccctcattg agctcgctga agttggcttc ctagcggtgt aggctggaat agactcttgg    240

caagctccgg gttggtatac tgggttaact ttgggaaatg caagtgttta tctccaggat    300

ctagccaccg gggtggtgta agccgcaaag aagttccacc aggtgagaag agtgatgacc    360

atccttttcc ttactatggt tatttcatac tttggttgca tgaaggctgc ccccatgaaa    420

gaagcaaaca tccgaggaca aggtggcttg gcctacccag gtgtgcggac ccatgggact    480

ctggagagcg tgaatgggcc caaggcaggt tcaagaggct tgacatcatt ggctgacact    540

ttcgaacacg tgatagaaga gctgttggat gaggaccaga aagttcggcc caatgaagaa    600

aacaataagg acgcagactt gtacacgtcc agggtgatgc tcagtagtca agtgcctttg    660

gagcctcctc ttctctttct gctggaggaa tacaaaaatt acctagatgc tgcaaacatg    720

tccatgaggg tccggcgcca ctctgaccct gcccgccgag gggagctgag cgtgtgtgac    780

agtattagtg agtgggtaac ggcagcagac aaaaagactg cagtggacat gtcgggcggg    840

acggtcacag tccttgaaaa ggtccctgta tcaaaaggcc aactgaagca atacttctac    900

gagaccaagt gcaatcccat gggttacaca aaagaaggct gcaggggcat agacaaaagg    960

cattggaact cccagtgccg aactacccag tcgtacgtgc gggcccttac catggatagc   1020

aaaaagagaa ttggctggcg attcataagg atagacactt cttgtgtatg tacattgacc   1080

attaaaaggg gaagatagtg gatttatgtt gtatagatta gattatattg agacaaaaat   1140

tatctatttg tatatataca taacagggta aattattcag ttaagaaaaa aataatttta   1200

tgaactgcat gtataaatga agtttataca gtacagtggt tctacaatct atttattgga   1260

catgtccatg accagaaggg aaacagtcat ttgcgcacaa cttaaaaagt ctgcattaca   1320

ttccttgata atgttgtggt ttgttgccgt tgccaagaac tgaaaacata aaaagttaaa   1380

aaaaataata aattgcatgc tgcttt                                        1406


<210>  7887
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  7887

Met Thr Ile Leu Phe Leu Thr Met Val Ile Ser Tyr Phe Gly Cys Met 
1               5                   10                  15


Lys Ala Ala Pro Met Lys Glu Ala Asn Ile Arg Gly Gln Gly Gly Leu 
            20                  25                  30


Ala Tyr Pro Gly Val Arg Thr His Gly Thr Leu Glu Ser Val Asn Gly 
        35                  40                  45


Pro Lys Ala Gly Ser Arg Gly Leu Thr Ser Leu Ala Asp Thr Phe Glu 
    50                  55                  60


His Val Ile Glu Glu Leu Leu Asp Glu Asp Gln Lys Val Arg Pro Asn 
65                  70                  75                  80


Glu Glu Asn Asn Lys Asp Ala Asp Leu Tyr Thr Ser Arg Val Met Leu 
                85                  90                  95


Ser Ser Gln Val Pro Leu Glu Pro Pro Leu Leu Phe Leu Leu Glu Glu 
            100                 105                 110


Tyr Lys Asn Tyr Leu Asp Ala Ala Asn Met Ser Met Arg Val Arg Arg 
        115                 120                 125


His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
    130                 135                 140


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
145                 150                 155                 160


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
                165                 170                 175


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
            180                 185                 190


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
        195                 200                 205


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
    210                 215                 220


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
225                 230                 235                 240


Leu Thr Ile Lys Arg Gly Arg 
                245


<210>  7888
<211>  1390
<212>  DNA
<213>  Homo sapiens

<400>  7888
tcattcatta gaatcacgta agaactcaaa aggaaacgtg tctctcggag tgagggcgtt     60

tgcgtaaatc tataggtttt tcgacatcga tgccagttgc tttgtcttct gtagtcgcca    120

aggtggttga gagtttaagc ttgcggatat tgcaaagggt tattagattc ataagtcaca    180

ccaagtggtg ggcgatccac tgagcaaagc cgaacttctc acatgatgac ttcaaacaag    240

acacattacc ttccagcatc tgttggggag acgagatttt aagacacttg agtctccagg    300

acagcaaagg cacaatgttc caccaggtga gaagagtgat gaccatcctt ttccttacta    360

tggttatttc atactttggt tgcatgaagg ctgcccccat gaaagaagca aacatccgag    420

gacaaggtgg cttggcctac ccaggtgtgc ggacccatgg gactctggag agcgtgaatg    480

ggcccaaggc aggttcaaga ggcttgacat cattggctga cactttcgaa cacgtgatag    540

aagagctgtt ggatgaggac cagaaagttc ggcccaatga agaaaacaat aaggacgcag    600

acttgtacac gtccagggtg atgctcagta gtcaagtgcc tttggagcct cctcttctct    660

ttctgctgga ggaatacaaa aattacctag atgctgcaaa catgtccatg agggtccggc    720

gccactctga ccctgcccgc cgaggggagc tgagcgtgtg tgacagtatt agtgagtggg    780

taacggcagc agacaaaaag actgcagtgg acatgtcggg cgggacggtc acagtccttg    840

aaaaggtccc tgtatcaaaa ggccaactga agcaatactt ctacgagacc aagtgcaatc    900

ccatgggtta cacaaaagaa ggctgcaggg gcatagacaa aaggcattgg aactcccagt    960

gccgaactac ccagtcgtac gtgcgggccc ttaccatgga tagcaaaaag agaattggct   1020

ggcgattcat aaggatagac acttcttgtg tatgtacatt gaccattaaa aggggaagat   1080

agtggattta tgttgtatag attagattat attgagacaa aaattatcta tttgtatata   1140

tacataacag ggtaaattat tcagttaaga aaaaaataat tttatgaact gcatgtataa   1200

atgaagttta tacagtacag tggttctaca atctatttat tggacatgtc catgaccaga   1260

agggaaacag tcatttgcgc acaacttaaa aagtctgcat tacattcctt gataatgttg   1320

tggtttgttg ccgttgccaa gaactgaaaa cataaaaagt taaaaaaaat aataaattgc   1380

atgctgcttt                                                          1390


<210>  7889
<211>  255
<212>  PRT
<213>  Homo sapiens

<400>  7889

Met Phe His Gln Val Arg Arg Val Met Thr Ile Leu Phe Leu Thr Met 
1               5                   10                  15


Val Ile Ser Tyr Phe Gly Cys Met Lys Ala Ala Pro Met Lys Glu Ala 
            20                  25                  30


Asn Ile Arg Gly Gln Gly Gly Leu Ala Tyr Pro Gly Val Arg Thr His 
        35                  40                  45


Gly Thr Leu Glu Ser Val Asn Gly Pro Lys Ala Gly Ser Arg Gly Leu 
    50                  55                  60


Thr Ser Leu Ala Asp Thr Phe Glu His Val Ile Glu Glu Leu Leu Asp 
65                  70                  75                  80


Glu Asp Gln Lys Val Arg Pro Asn Glu Glu Asn Asn Lys Asp Ala Asp 
                85                  90                  95


Leu Tyr Thr Ser Arg Val Met Leu Ser Ser Gln Val Pro Leu Glu Pro 
            100                 105                 110


Pro Leu Leu Phe Leu Leu Glu Glu Tyr Lys Asn Tyr Leu Asp Ala Ala 
        115                 120                 125


Asn Met Ser Met Arg Val Arg Arg His Ser Asp Pro Ala Arg Arg Gly 
    130                 135                 140


Glu Leu Ser Val Cys Asp Ser Ile Ser Glu Trp Val Thr Ala Ala Asp 
145                 150                 155                 160


Lys Lys Thr Ala Val Asp Met Ser Gly Gly Thr Val Thr Val Leu Glu 
                165                 170                 175


Lys Val Pro Val Ser Lys Gly Gln Leu Lys Gln Tyr Phe Tyr Glu Thr 
            180                 185                 190


Lys Cys Asn Pro Met Gly Tyr Thr Lys Glu Gly Cys Arg Gly Ile Asp 
        195                 200                 205


Lys Arg His Trp Asn Ser Gln Cys Arg Thr Thr Gln Ser Tyr Val Arg 
    210                 215                 220


Ala Leu Thr Met Asp Ser Lys Lys Arg Ile Gly Trp Arg Phe Ile Arg 
225                 230                 235                 240


Ile Asp Thr Ser Cys Val Cys Thr Leu Thr Ile Lys Arg Gly Arg 
                245                 250                 255


<210>  7890
<211>  2710
<212>  DNA
<213>  Homo sapiens

<400>  7890
gagttgcttc agcatcctgg tgttgctgtg ccgtgggtcc tgtgcggtca cttagccaag     60

atgcctgagg aaacccagac ccaagaccaa ccgatggagg aggaggaggt tgagacattc    120

gcctttcagg cagaaattgc ccagttgatg tcattgatca tcaatacttt ctactcgaac    180

aaagagatct ttctgagaga gctcatttca aattcatcag atgcattgga caaaatctgg    240

tatgaaagct tgacagatcc cagtaaatta gactctggga aagagctgca tattaacctt    300

ataccaaaca aacaagatca aactctcact attgtggata ctggaattgg aatgaccaag    360

gctgacttga tcaataacct tggtgaacgt atgggtcgtg gaacaaaggt tatcctacac    420

ctgaaagaag accaaactga gtacttggag gaacaaagaa taaaggagat tgtgaagaaa    480

cattctcagc ttattggata tcccattact ctttttgtgg agaaggaatg tgataaagaa    540

gtcagcgacg atgagactga agaaaaggaa gacaaagaag aagaaaaaga aaaagaagag    600

aaagagtcca aagacaaacc tgaaattgaa gatgttggtt ctgatgagga agaagaaaag    660

aaggatggtg acaagaagaa gaagaagact aaggaaaagt acatcgacca agaagaactc    720

aacaaaacaa agcccatctg gaccagaaat cccgacgata ttactaatga ggagtacgga    780

gaattctgca agaacttgac caatgactgg gaagatcact tggcagtgaa gcatttttca    840

gttgaaggac agttggaatt cagagccctt ctatttgtcc catgacgtgc tccttttgac    900

ctgtttgaaa acagaaagaa aaagaacaac atcaaattgt atgtacgcag agatttcatc    960

atggataact gtgaggagct aatccctgaa tatctgaact tcattagagg ggtggtagac   1020

tcggaggatc tccctctaaa catttcccgt gagatgttgc aacaaagtaa aattttgaaa   1080

gttatcagga aaaatttggt caaaaaatgc ttagaactct ttacagaact ggcggaagat   1140

aaagagaact gcaagaaatt ctatgagcag ttctctaaaa acataaagct tggaatacaa   1200

gaagactctc aaaatcggaa gaagctttca gagctgttaa ggtactacac gtctgcctct   1260

ggtgatgaga tggtttctct caaggactac tgcaccagaa tgaaggaaaa acagaaacat   1320

atctattata tcacaggtga gaccaaggac caggtagcta actcagcctt tgtggaacgt   1380

cttgggaaac atggcttaga agtgatctat atgattgagc ccattgatga gtactgtgtc   1440

caacagctga aggaatttga ggggaagact ttagtgccag tcaccaaaga aggcctggaa   1500

cttccagagg atgaagaaaa gaaaaagaaa taggaagaga aaaaacaatg tttgagaacc   1560

tctgcaaaac catgaaagac atattggaga aaaaagttga aaaggtggtt gtgtcaaacc   1620

gattggtgac gtctccatgc tgtattgtca caagcacata tggctggaca gaaaacatgg   1680

agagaatcat gaaagctcaa gccctaagag acaactcaac aatgggttat atggcagcca   1740

agaaacacct ggagataaat cctgatgatt ccattattga gaccttaagg caaaaggcag   1800

aggctgataa gaatgacaag tctgtgaagg atctgctcat cttgctttac gaaactgcac   1860

tcctgtcttc tggcttcagt ctggaagatc cccagacaca tgctaacagg acctacagga   1920

tgatcaaact tggtctgggt attgatgaag atgatcctgc tgctgatgat accagtgctg   1980

ctgtaactga agaaatgccg cccctcgaag gagatgacga cacatcatgc atggaagaag   2040

tagactaacc tctggctaag ggatgactta actgttcaat actctacaat tcctccgata   2100

atatatattc aaggatgttt ttctttattt ttgttaatat taaaaagtct gtacggcatg   2160

acaacaacta ctttaagggg aagataagat ttctgtctac taagtgatgc tgtgatacct   2220

taggcactaa agcagagcta gtaatgcttt ttgagtttca cgtcggttta ttttcacaga   2280

ttggggtaac gtgcgttgta agatgtatgt aacatgatgt taactttgtg gtctaaagtg   2340

tttagctgtc aagccggatt cctaagtaga ccaaatcttg ttatcgaagt gttcctgagc   2400

tataccttga tgtttagaaa agtatttgtt acatcttgta ggatctactt tttgaacttt   2460

tcatccccta tagttgacaa ttctgcatgt actagtcctc tagaaatagg ttaaactgaa   2520

gcaacttgat ggaaggatct ctccacaggg cttgttttcc aaagaaaagt attgtttgga   2580

ggagcaaagt tataagccta cctaagcata tcataaagct gtttaaaaat aactcagacc   2640

cggtcttgtg gatggaaatg tagtgctcga gtcacattct tcttatagtt gtaacaaata   2700

cagatgagtt                                                          2710


<210>  7891
<211>  274
<212>  PRT
<213>  Homo sapiens

<400>  7891

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Trp Tyr Glu Ser Leu 
    50                  55                  60


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80


Ile Pro Asn Lys Gln Asp Gln Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Glu Arg Met Gly 
            100                 105                 110


Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu Asp Gln Thr Glu Tyr 
        115                 120                 125


Leu Glu Glu Gln Arg Ile Lys Glu Ile Val Lys Lys His Ser Gln Leu 
    130                 135                 140


Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys Glu Cys Asp Lys Glu 
145                 150                 155                 160


Val Ser Asp Asp Glu Thr Glu Glu Lys Glu Asp Lys Glu Glu Glu Lys 
                165                 170                 175


Glu Lys Glu Glu Lys Glu Ser Lys Asp Lys Pro Glu Ile Glu Asp Val 
            180                 185                 190


Gly Ser Asp Glu Glu Glu Glu Lys Lys Asp Gly Asp Lys Lys Lys Lys 
        195                 200                 205


Lys Thr Lys Glu Lys Tyr Ile Asp Gln Glu Glu Leu Asn Lys Thr Lys 
    210                 215                 220


Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile Thr Asn Glu Glu Tyr Gly 
225                 230                 235                 240


Glu Phe Cys Lys Asn Leu Thr Asn Asp Trp Glu Asp His Leu Ala Val 
                245                 250                 255


Lys His Phe Ser Val Glu Gly Gln Leu Glu Phe Arg Ala Leu Leu Phe 
            260                 265                 270


Val Pro 



<210>  7892
<211>  2695
<212>  DNA
<213>  Homo sapiens

<400>  7892
tgagttgctt cagcatcctg gtgttgctgt gccgtgggtc ctgtgcggtc acttagccaa     60

gatgcctgag gaaacccaga cccaagacca accgatggag gaggaggagg ttgagacatt    120

cgcctttcag gcagaaattg cccagttgat gtcattgatc atcaatactt tctactcgaa    180

caaagagatc tttctgagag agctcatttc aaattcatca gatgcattgg acaaaatctg    240

gtatgaaagc ttgacagatc ccagtaaatt agactctggg aaagagctgc atattaacct    300

tataccaaac aaacaagatc aaactctcac tattgtggat actggaattg gaatgaccaa    360

ggctgacttg atcaataacc ttggtactat cgccaagtct gggaccaaag cgttcatgga    420

agctttgcag gctggtgcag atatctctat gattggccag ttcggtgtta gtttttattc    480

tgcttatttg gttgctgaga aagtaactgt gatcaccaaa cataatgatg atgagcagta    540

cgcctgggag tcctcagcag ggggatcatt cacagtgagg acagacacag gtgaacgtat    600

gggtcgtgga acaaagatgt tggttctgat gaggaagaag aaaagaagga tggtgacaag    660

aagaagaaga agactaagga aaagtacatc gaccaagaag aactcaacaa aacaaagccc    720

atctggacca gaaatcccga cgatattact aatgaggagt acggagaatt ctgcaagaac    780

ttgaccaatg actgggaaga tcacttggca gtgaagcatt tttcagttga aggacagttg    840

gaattcagag cccttctatt tgtcccatga cgtgctcctt ttgacctgtt tgaaaacaga    900

aagaaaaaga acaacatcaa attgtatgta cgcagagatt tcatcatgga taactgtgag    960

gagctaatcc ctgaatatct gaacttcatt agaggggtgg tagactcgga ggatctccct   1020

ctaaacattt cccgtgagat gttgcaacaa agtaaaattt tgaaagttat caggaaaaat   1080

ttggtcaaaa aatgcttaga actctttaca gaactggcgg aagataaaga gaactgcaag   1140

aaattctatg agcagttctc taaaaacata aagcttggaa tacaagaaga ctctcaaaat   1200

cggaagaagc tttcagagct gttaaggtac tacacgtctg cctctggtga tgagatggtt   1260

tctctcaagg actactgcac cagaatgaag gaaaaacaga aacatatcta ttatatcaca   1320

ggtgagacca aggaccaggt agctaactca gcctttgtgg aacgtcttgg gaaacatggc   1380

ttagaagtga tctatatgat tgagcccatt gatgagtact gtgtccaaca gctgaaggaa   1440

tttgagggga agactttagt gccagtcacc aaagaaggcc tggaacttcc agaggatgaa   1500

gaaaagaaaa agaaatagga agagaaaaaa caatgtttga gaacctctgc aaaaccatga   1560

aagacatatt ggagaaaaaa gttgaaaagg tggttgtgtc aaaccgattg gtgacgtctc   1620

catgctgtat tgtcacaagc acatatggct ggacagaaaa catggagaga atcatgaaag   1680

ctcaagccct aagagacaac tcaacaatgg gttatatggc agccaagaaa cacctggaga   1740

taaatcctga tgattccatt attgagacct taaggcaaaa ggcagaggct gataagaatg   1800

acaagtctgt gaaggatctg ctcatcttgc tttacgaaac tgcactcctg tcttctggct   1860

tcagtctgga agatccccag acacatgcta acaggaccta caggatgatc aaacttggtc   1920

tgggtattga tgaagatgat cctgctgctg atgataccag tgctgctgta actgaagaaa   1980

tgccgcccct cgaaggagat gacgacacat catgcatgga agaagtagac taacctctgg   2040

ctaagggatg acttaactgt tcaatactct acaattcctc cgataatata tattcaagga   2100

tgtttttctt tatttttgtt aatattaaaa agtctgtacg gcatgacaac aactacttta   2160

aggggaagat aagatttctg tctactaagt gatgctgtga taccttaggc actaaagcag   2220

agctagtaat gctttttgag tttcacgtcg gtttattttc acagattggg gtaacgtgcg   2280

ttgtaagatg tatgtaacat gatgttaact ttgtggtcta aagtgtttag ctgtcaagcc   2340

ggattcctaa gtagaccaaa tcttgttatc gaagtgttcc tgagctatac cttgatgttt   2400

agaaaagtat ttgttacatc ttgtaggatc tactttttga acttttcatc ccctatagtt   2460

gacaattctg catgtactag tcctctagaa ataggttaaa ctgaagcaac ttgatggaag   2520

gatctctcca cagggcttgt tttccaaaga aaagtattgt ttggaggagc aaagttataa   2580

gcctacctaa gcatatcata aagctgttta aaaataactc agacccggtc ttgtggatgg   2640

aaatgtagtg ctcgagtcac attcttctta tagttgtaac aaatacagat gagtt        2695


<210>  7893
<211>  240
<212>  PRT
<213>  Homo sapiens

<400>  7893

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Trp Tyr Glu Ser Leu 
    50                  55                  60


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80


Ile Pro Asn Lys Gln Asp Gln Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys 
            100                 105                 110


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile 
        115                 120                 125


Ser Met Ile Gly Gln Phe Gly Val Ser Phe Tyr Ser Ala Tyr Leu Val 
    130                 135                 140


Ala Glu Lys Val Thr Val Ile Thr Lys His Asn Asp Asp Glu Gln Tyr 
145                 150                 155                 160


Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr 
                165                 170                 175


Gly Glu Arg Met Gly Arg Gly Thr Lys Met Leu Val Leu Met Arg Lys 
            180                 185                 190


Lys Lys Arg Arg Met Val Thr Arg Arg Arg Arg Arg Leu Arg Lys Ser 
        195                 200                 205


Thr Ser Thr Lys Lys Asn Ser Thr Lys Gln Ser Pro Ser Gly Pro Glu 
    210                 215                 220


Ile Pro Thr Ile Leu Leu Met Arg Ser Thr Glu Asn Ser Ala Arg Thr 
225                 230                 235                 240


<210>  7894
<211>  2692
<212>  DNA
<213>  Homo sapiens

<400>  7894
tgagttgctt cagcatcctg gtgttgctgt gccgtgggtc ctgtgcggtc acttagccaa     60

gatgcctgag gaaacccaga cccaagacca accgatggag gaggaggagg ttgagacatt    120

cgcctttcag gcagaaattg cccagttgat gtcattgatc atcaatactt tctactcgaa    180

caaagagatc tttctgagag agctcatttc aaattcatca gatgcattgg acaaaatctg    240

gtatgaaagc ttgacagatc ccagtaaatt agactctggg aaagagctgc atattaacct    300

tataccaaac aaacaagatc aaactctcac tattgtggat actggaattg gaatgaccaa    360

ggctgacttg atcaataacc ttggtactat cgccaagtct gggaccaaag cgttcatgga    420

agctttgcag gctggtgcag atatctctat gattggccag ttcggtgtta gtttttattc    480

tgcttatttg gttgctgaga aagtaactgt gatcaccaaa cataatgatg atgagcaact    540

gaagaaaagg aagacaaaga agaagaaaaa gaaaaagaag agaaagagtc caaagacaaa    600

cctgaaattg aagatgttgg ttctgatgag gaagaagaaa agaaggatgg tgacaagaag    660

aagaagaaga ctaaggaaaa gtacatcgac caagaagaac tcaacaaaac aaagcccatc    720

tggaccagaa atcccgacga tattactaat gaggagtacg gagaattctg caagaacttg    780

accaatgact gggaagatca cttggcagtg aagcattttt cagttgaagg acagttggaa    840

ttcagagccc ttctatttgt cccatgacgt gctccttttg acctgtttga aaacagaaag    900

aaaaagaaca acatcaaatt gtatgtacgc agagatttca tcatggataa ctgtgaggag    960

ctaatccctg aatatctgaa cttcattaga ggggtggtag actcggagga tctccctcta   1020

aacatttccc gtgagatgtt gcaacaaagt aaaattttga aagttatcag gaaaaatttg   1080

gtcaaaaaat gcttagaact ctttacagaa ctggcggaag ataaagagaa ctgcaagaaa   1140

ttctatgagc agttctctaa aaacataaag cttggaatac aagaagactc tcaaaatcgg   1200

aagaagcttt cagagctgtt aaggtactac acgtctgcct ctggtgatga gatggtttct   1260

ctcaaggact actgcaccag aatgaaggaa aaacagaaac atatctatta tatcacaggt   1320

gagaccaagg accaggtagc taactcagcc tttgtggaac gtcttgggaa acatggctta   1380

gaagtgatct atatgattga gcccattgat gagtactgtg tccaacagct gaaggaattt   1440

gaggggaaga ctttagtgcc agtcaccaaa gaaggcctgg aacttccaga ggatgaagaa   1500

aagaaaaaga aataggaaga gaaaaaacaa tgtttgagaa cctctgcaaa accatgaaag   1560

acatattgga gaaaaaagtt gaaaaggtgg ttgtgtcaaa ccgattggtg acgtctccat   1620

gctgtattgt cacaagcaca tatggctgga cagaaaacat ggagagaatc atgaaagctc   1680

aagccctaag agacaactca acaatgggtt atatggcagc caagaaacac ctggagataa   1740

atcctgatga ttccattatt gagaccttaa ggcaaaaggc agaggctgat aagaatgaca   1800

agtctgtgaa ggatctgctc atcttgcttt acgaaactgc actcctgtct tctggcttca   1860

gtctggaaga tccccagaca catgctaaca ggacctacag gatgatcaaa cttggtctgg   1920

gtattgatga agatgatcct gctgctgatg ataccagtgc tgctgtaact gaagaaatgc   1980

cgcccctcga aggagatgac gacacatcat gcatggaaga agtagactaa cctctggcta   2040

agggatgact taactgttca atactctaca attcctccga taatatatat tcaaggatgt   2100

ttttctttat ttttgttaat attaaaaagt ctgtacggca tgacaacaac tactttaagg   2160

ggaagataag atttctgtct actaagtgat gctgtgatac cttaggcact aaagcagagc   2220

tagtaatgct ttttgagttt cacgtcggtt tattttcaca gattggggta acgtgcgttg   2280

taagatgtat gtaacatgat gttaactttg tggtctaaag tgtttagctg tcaagccgga   2340

ttcctaagta gaccaaatct tgttatcgaa gtgttcctga gctatacctt gatgtttaga   2400

aaagtatttg ttacatcttg taggatctac tttttgaact tttcatcccc tatagttgac   2460

aattctgcat gtactagtcc tctagaaata ggttaaactg aagcaacttg atggaaggat   2520

ctctccacag ggcttgtttt ccaaagaaaa gtattgtttg gaggagcaaa gttataagcc   2580

tacctaagca tatcataaag ctgtttaaaa ataactcaga cccggtcttg tggatggaaa   2640

tgtagtgctc gagtcacatt cttcttatag ttgtaacaaa tacagatgag tt           2692


<210>  7895
<211>  239
<212>  PRT
<213>  Homo sapiens

<400>  7895

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Trp Tyr Glu Ser Leu 
    50                  55                  60


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80


Ile Pro Asn Lys Gln Asp Gln Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys 
            100                 105                 110


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile 
        115                 120                 125


Ser Met Ile Gly Gln Phe Gly Val Ser Phe Tyr Ser Ala Tyr Leu Val 
    130                 135                 140


Ala Glu Lys Val Thr Val Ile Thr Lys His Asn Asp Asp Glu Gln Leu 
145                 150                 155                 160


Lys Lys Arg Lys Thr Lys Lys Lys Lys Lys Lys Lys Lys Arg Lys Ser 
                165                 170                 175


Pro Lys Thr Asn Leu Lys Leu Lys Met Leu Val Leu Met Arg Lys Lys 
            180                 185                 190


Lys Arg Arg Met Val Thr Arg Arg Arg Arg Arg Leu Arg Lys Ser Thr 
        195                 200                 205


Ser Thr Lys Lys Asn Ser Thr Lys Gln Ser Pro Ser Gly Pro Glu Ile 
    210                 215                 220


Pro Thr Ile Leu Leu Met Arg Ser Thr Glu Asn Ser Ala Arg Thr 
225                 230                 235


<210>  7896
<211>  3198
<212>  DNA
<213>  Homo sapiens

<400>  7896
aattaatttt gattacattt aaaattctat atggcaaaaa taccataatt aaagataaaa     60

ggcaaagaac aaattgggaa aaatattttt caacatatat aaccaagggc taatttctct    120

aacacctaaa aagttcttat aaatcaataa aaagaaaacc aacatctcaa tggaaaaaga    180

acaaagctca taaagagttc acagaaaaag gatatacaaa tggctttaaa catgtgaaag    240

aatgttcaac ttcactcaca ataagaaaaa atacaaatta tgagttgctt cagcatcctg    300

gtgttgctgt gccgtgggtc ctgtgcggtc acttagccaa gatgcctgag gaaacccaga    360

cccaagacca accgatggag gaggaggagg ttgagacatt cgcctttcag gcagaaattg    420

cccagttgat gtcattgatc atcaatactt tctactcgaa caaagagatc tttctgagag    480

agctcatttc aaattcatca gatgcattgg acaaaatctg gtatgaaagc ttgacagatc    540

ccagtaaatt agactctggg aaagagctgc atattaacct tataccaaac aaacaagatc    600

aaactctcac tattgtggat actggaattg gaatgaccaa ggctgacttg atcaataacc    660

ttggtactat cgccaagtct gggaccaaag cgttcatgga agctttgcag gctggtgcag    720

atatctctat gattggccag ttcggtgtta gtttttattc tgcttatttg gttgctgaga    780

aagtaactgt gatcaccaaa cataatgatg atgagcagta cgcctgggag tcctcagcag    840

ggggatcatt cacagtgagg acagacacag gtgaacgtat gggtcgtgga acaaaggtta    900

tcctacacct gaaagaagac caaactgagt acttggagga acaaagaata aaggagattg    960

tgaagaaaca ttctcagctt attggatatc ccattactct ttttgtggag aaggaatgtg   1020

ataaagaagt cagcgacgat gagactgaag aaaaggaaga caaagaagaa gaaaaagaaa   1080

aagaagagaa agagtccaaa gacaaacctg aaattgaaga tgttggttct gatgaggaag   1140

aagaaaagaa ggatggtgac aagaagaaga agaagactaa ggaaaagtac atcgaccaag   1200

aagaactcaa caaaacaaag cccatctgga ccagaaatcc cgacgatatt actaatgagg   1260

agtacggaga attctgcaag aacttgacca atgactggga agatcacttg gcagtgaagc   1320

atttttcagt tgaaggacag ttggaattca gagcccttct atttgtccca tgacgtgctc   1380

cttttgacct gtttgaaaac agaaagaaaa agaacaacat caaattgtat gtacgcagag   1440

atttcatcat ggataactgt gaggagctaa tccctgaata tctgaacttc attagagggg   1500

tggtagactc ggaggatctc cctctaaaca tttcccgtga gatgttgcaa caaagtaaaa   1560

ttttgaaagt tatcaggaaa aatttggtca aaaaatgctt agaactcttt acagaactgg   1620

cggaagataa agagaactgc aagaaattct atgagcagtt ctctaaaaac ataaagcttg   1680

gaatacaaga agactctcaa aatcggaaga agctttcaga gctgttaagg tactacacgt   1740

ctgcctctgg tgatgagatg gtttctctca aggactactg caccagaatg aaggaaaaac   1800

agaaacatat ctattatatc acaggtgaga ccaaggacca ggtagctaac tcagcctttg   1860

tggaacgtct tgggaaacat ggcttagaag tgatctatat gattgagccc attgatgagt   1920

actgtgtcca acagctgaag gaatttgagg ggaagacttt agtgccagtc accaaagaag   1980

gcctggaact tccagaggat gaagaaaaga aaaagaaata ggaagagaaa aaacaatgtt   2040

tgagaacctc tgcaaaacca tgaaagacat attggagaaa aaagttgaaa aggtggttgt   2100

gtcaaaccga ttggtgacgt ctccatgctg tattgtcaca agcacatatg gctggacaga   2160

aaacatggag agaatcatga aagctcaagc cctaagagac aactcaacaa tgggttatat   2220

ggcagccaag aaacacctgg agataaatcc tgatgattcc attattgaga ccttaaggca   2280

aaaggcagag gctgataaga atgacaagtc tgtgaaggat ctgctcatct tgctttacga   2340

aactgcactc ctgtcttctg gcttcagtct ggaagatccc cagacacatg ctaacaggac   2400

ctacaggatg atcaaacttg gtctgggtat tgatgaagat gatcctgctg ctgatgatac   2460

cagtgctgct gtaactgaag aaatgccgcc cctcgaagga gatgacgaca catcatgcat   2520

ggaagaagta gactaacctc tggctaaggg atgacttaac tgttcaatac tctacaattc   2580

ctccgataat atatattcaa ggatgttttt ctttattttt gttaatatta aaaagtctgt   2640

acggcatgac aacaactact ttaaggggaa gataagattt ctgtctacta agtgatgctg   2700

tgatacctta ggcactaaag cagagctagt aatgcttttt gagtttcacg tcggtttatt   2760

ttcacagatt ggggtaacgt gcgttgtaag atgtatgtaa catgatgtta actttgtggt   2820

ctaaagtgtt tagctgtcaa gccggattcc taagtagacc aaatcttgtt atcgaagtgt   2880

tcctgagcta taccttgatg tttagaaaag tatttgttac atcttgtagg atctactttt   2940

tgaacttttc atcccctata gttgacaatt ctgcatgtac tagtcctcta gaaataggtt   3000

aaactgaagc aacttgatgg aaggatctct ccacagggct tgttttccaa agaaaagtat   3060

tgtttggagg agcaaagtta taagcctacc taagcatatc ataaagctgt ttaaaaataa   3120

ctcagacccg gtcttgtgga tggaaatgta gtgctcgagt cacattcttc ttatagttgt   3180

aacaaataca gatgagtt                                                 3198


<210>  7897
<211>  343
<212>  PRT
<213>  Homo sapiens

<400>  7897

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Trp Tyr Glu Ser Leu 
    50                  55                  60


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80


Ile Pro Asn Lys Gln Asp Gln Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys 
            100                 105                 110


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile 
        115                 120                 125


Ser Met Ile Gly Gln Phe Gly Val Ser Phe Tyr Ser Ala Tyr Leu Val 
    130                 135                 140


Ala Glu Lys Val Thr Val Ile Thr Lys His Asn Asp Asp Glu Gln Tyr 
145                 150                 155                 160


Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr 
                165                 170                 175


Gly Glu Arg Met Gly Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu 
            180                 185                 190


Asp Gln Thr Glu Tyr Leu Glu Glu Gln Arg Ile Lys Glu Ile Val Lys 
        195                 200                 205


Lys His Ser Gln Leu Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys 
    210                 215                 220


Glu Cys Asp Lys Glu Val Ser Asp Asp Glu Thr Glu Glu Lys Glu Asp 
225                 230                 235                 240


Lys Glu Glu Glu Lys Glu Lys Glu Glu Lys Glu Ser Lys Asp Lys Pro 
                245                 250                 255


Glu Ile Glu Asp Val Gly Ser Asp Glu Glu Glu Glu Lys Lys Asp Gly 
            260                 265                 270


Asp Lys Lys Lys Lys Lys Thr Lys Glu Lys Tyr Ile Asp Gln Glu Glu 
        275                 280                 285


Leu Asn Lys Thr Lys Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile Thr 
    290                 295                 300


Asn Glu Glu Tyr Gly Glu Phe Cys Lys Asn Leu Thr Asn Asp Trp Glu 
305                 310                 315                 320


Asp His Leu Ala Val Lys His Phe Ser Val Glu Gly Gln Leu Glu Phe 
                325                 330                 335


Arg Ala Leu Leu Phe Val Pro 
            340


<210>  7898
<211>  2312
<212>  DNA
<213>  Homo sapiens

<400>  7898
ggagctgctg gtgggaggca gccacttgag atcaccaggc ctcctgtaga ccggcgggtg     60

cagggcccgg tcccagagtt aagggaaagt cgtttggaaa ccccaggcca acaggaccct    120

ttggcagctg aggctggaaa cagcggaacc aaaggcagac ggtcctcagt tgcttgggcg    180

gacgtggacc caatctgtcc gtccttacaa gtttccccca ggggcaggac ctagacgcgc    240

ggcgcattca ggttctcctg gaccgtagtg gtagtcgctg gcccgagtta gaggccagct    300

gagaagtctt cgtgcttcag atttgtttac ctacaaaatg cttcggtatc catatttttg    360

tagaatgtat aaagaatgcc tttcatgttg gttggaatct ggcataccta atttaggtgt    420

ctggccaaac agaatacata ctacagcaga aaaatataga gaatatgaag cccgggagca    480

aacagatcaa actcaagccc aggagttaca cagatctcaa gatagagatt ttgaaactat    540

ggctaaatta catattccag taatggtgga tgaagttgtt cattgtttgt caccacaaaa    600

aggacagatt tttctagata tgacatttgg ttcgggaggg cacacaaaag ccattctgca    660

gaaggagtca gatattgttc tctatgcctt ggacagagac ccaacagctt atgcattagc    720

tgaacatctt tcagagttgt atcctaaaca aatccgagct atgctgggcc agttcagcca    780

ggcagaagcc ttattaatga aagctggagt gcagccagga acttttgatg gagttcttat    840

ggatcttggg tgttcctcca tgcaacttga tactcctgaa agaggttttt cccttcggaa    900

agatggccct ttggacatga gaatggatgg tggcagatca acaggcactt gcatctatcc    960

taagaacata cggggaggag aagcatgcca agaaaatcgc ttcagcaatt gttcaggcac   1020

gcagcatcta ccccatcacc agaacccagc agcttgccag catcgttgca ggagcatttc   1080

ctccctctgc tatttataca cggaaagact tactacagcg atctacccat attgccacca   1140

agactttcca ggctcttcgc atatttgtga acaatgagct caatgaactc tacacgggac   1200

tgaagacagc tcagaagttt ctgagacctg gtggtcgtct tgttgccctc tccttccatt   1260

cactagagga tcgcatcgtc aaaagatttt tgcttggaat aagcatgaca gaaagattta   1320

acctaagtgt tagacaacaa gtgatgaaaa catctcaatt gggttcagat cacgaaaaca   1380

cggaagaagt ctctatgaga agagctcctt taatgtggga attgatacac aagaaggtac   1440

ttagtccaca agatcaggat gtacaagata accccagagg gcgctcagcc aagcttagag   1500

cagctatcaa attataagtt atcatcatct tattcttcaa atttttttct cacaatttct   1560

ctaatcttta ctcatgttat gtccctgaat gtcttggtat aggtttaagt gtgggacagt   1620

ctgaaaattg atagcattta gcatttcttt tttctcaaaa agaaactgta ggaaatacat   1680

gacagagaaa gttacactca gggagcagca gcacctccag actggaaaaa tatgttaatc   1740

tttgcatcat attggactct tgaaggcaat ccttcctctg gccaggaaat tttttaaaaa   1800

ataatactgt gttgtgttta tctaaatacg taaactcaag ctaccaaaga gaaagatgtt   1860

gtaatcatat ctgcatgtcc taaattttga atttagatat tccaatttgc atcagtcttt   1920

ctgtggctca aataatgatg attatggaat gaattttaat gtccctactt gtgaataatt   1980

agctttctca aatgtaggct ttttacaaat tttaaatttt aaaatattag tttaaatgtg   2040

tgttatactg ataaaatttc atctttcaaa ttatagtcta ttattttaaa gggatttttc   2100

agtatgatat gggccatttt gttcatctat cgcaaagtaa aaatgtaaaa tccttacaga   2160

gaattgtttc acaaaactta tatttcatgt caattgtatt tattttaata atagctcaca   2220

atgcctttag taagtaataa agtctcttat tagaatcttg tattttttaa ttgagctaat   2280

caaaataatt cagccaagtc tatttgaaat ag                                 2312


<210>  7899
<211>  279
<212>  PRT
<213>  Homo sapiens

<400>  7899

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Ser Thr Gly Thr Cys Ile Tyr Pro 
        195                 200                 205


Lys Asn Ile Arg Gly Gly Glu Ala Cys Gln Glu Asn Arg Phe Ser Asn 
    210                 215                 220


Cys Ser Gly Thr Gln His Leu Pro His His Gln Asn Pro Ala Ala Cys 
225                 230                 235                 240


Gln His Arg Cys Arg Ser Ile Ser Ser Leu Cys Tyr Leu Tyr Thr Glu 
                245                 250                 255


Arg Leu Thr Thr Ala Ile Tyr Pro Tyr Cys His Gln Asp Phe Pro Gly 
            260                 265                 270


Ser Ser His Ile Cys Glu Gln 
        275


<210>  7900
<211>  2388
<212>  DNA
<213>  Homo sapiens

<400>  7900
agtttccccc aggggcagga cctagacgcg cggcgcattc aggttctcct ggaccgtagt     60

ggtagtcgct ggcccgagtt agaggccagc tgagaagtct tcgtgcttca gatttgttta    120

cctacaaaat gcttcggtat ccatattttt gtagaatgta taaagaatgc ctttcatgtt    180

ggttggaatc tggcatacct aatttaggtg tctggccaaa cagaatacat actacagcag    240

aaaaatatag agaatatgaa gcccgggagc aaacagatca aactcaagcc caggagttac    300

acagatctca agatagagat tttgaaacta tggctaaatt acatattcca gtaatggtgg    360

atgaagttgt tcattgtttg tcaccacaaa aaggacagat ttttctagat atgacatttg    420

gttcgggagg gcacacaaaa gccattctgc agaaggagtc agatattgtt ctctatgcct    480

tggacagaga cccaacagct tatgcattag ctgaacatct ttcagagttg tatcctaaac    540

aaatccgagc tatgctgggc cagttcagcc aggcagaagc cttattaatg aaagctggag    600

tgcagccagg aacttttgat ggagttctta tggatcttgg gtgttcctcc atgcaacttg    660

atactcctga aagaggtttt tcccttcgga aagatggccc tttggacatg agaatggatg    720

gtggcagatc aacaggcact tgcatctatc ctaagaacat acggggagga gaagcatgcc    780

aagaaaatcg cttcagcaat tgttcaggca cgcagcatct accccatcac cagaacccag    840

cagcttgcca gcatcgttgc aggagcattt cctccctctg ctatttatac acggaaagac    900

ttactacagc gatctaccca tattgccacc aagactttcc aggctcttcg catatttgtg    960

aacaatgagc tcaatgaact ctacacggga ctgaagacag ctcagaagtt tctgagacct   1020

ggtggtcgtc ttgttgccct ctccttccat tcactagagg atcgcatcgt caaaagattt   1080

ttgcttggaa taagcatgac agaaagattt aacctaagtg ttagacaaca agtgatgaaa   1140

acatctcaat tgggttcaga tcacgaaaac acggaagaag tctctatgag aagagctcct   1200

ttaatgtggg aattgataca caagaaggta cttagtccac aagatcagga tgtacaagat   1260

aaccccagag ggcgctcagc caagcttaga gcagctatca aattataagt tatcatcatc   1320

ttattcttca aatttttttc tcacaatttc tctaatcttt actcatgtta tgtccctgaa   1380

tgtcttggta taggtttaag tgtgggacag tctgaaaatt gatagcattt agcatttctt   1440

ttttctcaaa aagaaactgt aggaaataca tgacagagaa agttacactc agggagcagc   1500

agcacctcca gactggaaaa atatgttaat ctttgcatca tattggactc ttgaaggcaa   1560

tccttcctct ggccaggaaa ttttttaaaa aataatactg tgttgtgttt atctaaatac   1620

gtaaactcaa gctaccaaag agaaagatgt tgtaatcata tctgcatgtc ctaaattttg   1680

aatttagata ttccaatttg catcagtctt tctgtggctc aaataatgat gattatggaa   1740

tgaattttaa tgtccctact tgtgaataat tagctttctc aaatgtaggc tttttacaaa   1800

ttttaaattt taaaatatta gtttaaatgt gtgttatact gataaaattt catctttcaa   1860

attatagtct attattttaa agggattttt cagtatgata tgggccattt tgttcatcta   1920

tcgcaaagta aaaatgtaaa atccttacag agaattgttt cacaaaactt atatttcatg   1980

tcaattgtat ttattttaat aatagctcac aatgccttta gtaagtaata aagtctctta   2040

ttagaatctt gtatttttta attgagctaa tcaaaataat tcagccaagt ctatttgaaa   2100

tagaaaactg tctatttaat atagtaaaat caatgctccc ttaatgttgt tacaaagata   2160

tggtaactgt aatatgggta aaagtttatt caagaaaaga gtacttggta gaagattctt   2220

taacaaattg aggagattga ttcataattc acatgtcaat tttttatagt aatatgtact   2280

tctaatttat tatttatact taaattgtga cctgaaagat gagttggaga taattagtca   2340

aagggcacat ggagtatgga agggggcatg ttgattaacc atacatag                2388


<210>  7901
<211>  279
<212>  PRT
<213>  Homo sapiens

<400>  7901

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Ser Thr Gly Thr Cys Ile Tyr Pro 
        195                 200                 205


Lys Asn Ile Arg Gly Gly Glu Ala Cys Gln Glu Asn Arg Phe Ser Asn 
    210                 215                 220


Cys Ser Gly Thr Gln His Leu Pro His His Gln Asn Pro Ala Ala Cys 
225                 230                 235                 240


Gln His Arg Cys Arg Ser Ile Ser Ser Leu Cys Tyr Leu Tyr Thr Glu 
                245                 250                 255


Arg Leu Thr Thr Ala Ile Tyr Pro Tyr Cys His Gln Asp Phe Pro Gly 
            260                 265                 270


Ser Ser His Ile Cys Glu Gln 
        275


<210>  7902
<211>  4068
<212>  DNA
<213>  Homo sapiens

<400>  7902
ctagacgcgc ggcgcattca ggttctcctg gaccgtagtg gtagtcgctg gcccgagtta     60

gaggccagct gagaagtctt cgtgcttcag atttgtttac ctacaaaatg cttcggtatc    120

catatttttg tagaatgtat aaagaatgcc tttcatgttg gttggaatct ggcataccta    180

atttaggtgt ctggccaaac agaatacata ctacagcaga aaaatataga gaatatgaag    240

cccgggagca aacagatcaa actcaagccc aggagttaca cagatctcaa gatagagatt    300

ttgaaactat ggctaaatta catattccag taatggtgga tgaagttgtt cattgtttgt    360

caccacaaaa aggacagatt tttctagata tgacatttgg ttcgggaggg cacacaaaag    420

ccattctgca gaaggagtca gatattgttc tctatgcctt ggacagagac ccaacagctt    480

atgcattagc tgaacatctt tcagagttgt atcctaaaca aatccgagct atgctgggcc    540

agttcagcca ggcagaagcc ttattaatga aagctggagt gcagccagga acttttgatg    600

gagttcttat ggatcttggg tgttcctcca tgcaacttga tactcctgaa agaggttttt    660

cccttcggaa agatggccct ttggacatga gaatggatgg tggcaggtac cctgacatgc    720

ccactgctgc tgatgttgtg aatgctttag atcaacaggc acttgcatct atcctaagaa    780

catacgggga ggagaagcat gccaagaaaa tcgcttcagc aattgttcag gcacgcagca    840

tctaccccat caccagaacc cagcagcttg ccagcatcgt tgcagaatac tctgaaacat    900

atttcccagt ggcccaaact ctttattagg aaaatggacg aattgaatag caaatggagc    960

atttcctccc tctgctattt atacacggaa agacttacta cagcgatcta cccatattgc   1020

caccaagact ttccaggctc ttcgcatatt tgtgaacaat gagctcaatg aactctacac   1080

gggactgaag acagctcaga agtttctgag acctggtggt cgtcttgttg ccctctcctt   1140

ccattcacta gaggatcgca tcgtcaaaag atttttgctt ggaataagca tgacagaaag   1200

atttaaccta agtgttagac aacaagtgat gaaaacatct caattgggtt cagatcacga   1260

aaacacggaa gaagtctcta tgagaagagc tcctttaatg tgggaattga tacacaagaa   1320

ggtacttagt ccacaagatc aggatgtaca agataacccc agagggcgct cagccaagct   1380

tagagcagct atcaaattat aagttatcat catcttattc ttcaaatttt tttctcacaa   1440

tttctctaat ctttactcat gttatgtccc tgaatgtctt ggtataggtt taagtgtggg   1500

acagtctgaa aattgatagc atttagcatt tcttttttct caaaaagaaa ctgtaggaaa   1560

tacatgacag agaaagttac actcagggag cagcagcacc tccagactgg aaaaatatgt   1620

taatctttgc atcatattgg actcttgaag gcaatccttc ctctggccag gaaatttttt   1680

aaaaaataat actgtgttgt gtttatctaa atacgtaaac tcaagctacc aaagagaaag   1740

atgttgtaat catatctgca tgtcctaaat tttgaattta gatattccaa tttgcatcag   1800

tctttctgtg gctcaaataa tgatgattat ggaatgaatt ttaatgtccc tacttgtgaa   1860

taattagctt tctcaaatgt aggcttttta caaattttaa attttaaaat attagtttaa   1920

atgtgtgtta tactgataaa atttcatctt tcaaattata gtctattatt ttaaagggat   1980

ttttcagtat gatatgggcc attttgttca tctatcgcaa agtaaaaatg taaaatcctt   2040

acagagaatt gtttcacaaa acttatattt catgtcaatt gtatttattt taataatagc   2100

tcacaatgcc tttagtaagt aataaagtct cttattagaa tcttgtattt tttaattgag   2160

ctaatcaaaa taattcagcc aagtctattt gaaatagaaa actgtctatt taatatagta   2220

aaatcaatgc tcccttaatg ttgttacaaa gatatggtaa ctgtaatatg ggtaaaagtt   2280

tattcaagaa aagagtactt ggtagaagat tctttaacaa attgaggaga ttgattcata   2340

attcacatgt caatttttta tagtaatatg tacttctaat ttattattta tacttaaatt   2400

gtgacctgaa agatgagttg gagataatta gtcaaagggc acatggagta tggaaggggg   2460

catgttgatt aaccatacat agaaataaat attctcttag ttatccttga aatcatattt   2520

atactattaa tttgctcagt gcactttttt caaatacaga aaaaagattc tccattatag   2580

ttacaaattt taggttggtg aatccaagtg aatgaaatat cagcataact atgtgggcaa   2640

aatagataga attaaatgca tgaattttcc tcagacttat tttatctgcc tctgtaatat   2700

ttaactttag tacccaggct tgttcactac ttctgcttta caggctttat ttaaatctga   2760

acaatcctac agggaaatca gaattaggaa aaaaatctgg agaacaatat ggttgaaata   2820

gaaacaagag aatgcaccta ggttaattcc ctgaatccta cttgaacatt gtataaattt   2880

ctctttgcat ataatacata tttgtgaatg agacatattc ccaaaaaatt cttatctctg   2940

tatgtgattg gaaaagaaaa gatcacattt gtatattcaa caatctttca cctatttcat   3000

aagtcatttt ttcaccctgt atagtatggg aattattttt tatgttaaat agaaactgaa   3060

tgtactgggt tgaatggtgt cctctccaaa attcatgtac ttcctggagc ctcagtatgt   3120

gaccttattt ggaaatactg tggttgtggt tgtaagtagc taagatgagg tcatactgga   3180

gcagggcagg cccttaatcc aatatgactg gtgttcctta taagagaaga tagggcgggc   3240

atggtggctc acgcctgtaa tcccagcact gtgggaggcc aagccaggca aatcgcttga   3300

ggctgaggag ttcaagacca gcctggccaa catggcgaaa acccatctct actaaaaata   3360

aaattagcca tgcgtggtgc ttgtaatgtc agctacccag gagtctgagg cacaagaatc   3420

actcgaacct gggaggtgga ggttgcgaga tcacaccact gcactccagt gtgagcaaca   3480

gaacgagact ctgtctcaaa aaaaaaaaaa aaaaggaaga aagagaagat agagacacag   3540

gggagaatgc cacatgaagc tggaggcaga gattggagtg atacattgtg ggaaccctca   3600

gaagatagga aaaaagcatg gaatagattc tccctcagag ttccagtagt tgccaaccct   3660

gctaacatgg ttttgcacat ctagcatcca gaacagtgag aatgtatttc tgctgtttta   3720

aggtacccag ttcatggtaa tttgttacag caatcctagg aagctaatac tctgacagaa   3780

aaaaatcttg gataatatgc atgagaaaaa tccttcaata aacacaaaat tggtttcaaa   3840

atgttttcat gtaaaaataa attaactttt ctgtaattag attgtgtttt atagtaattc   3900

ttgcctgctt cttagtcttt gttgtaggat gcataataaa atacatgaat gagttttaaa   3960

tggttagctt tggagaatgg ttttgggaag ttcctacagt acacagaaat aaaagctaat   4020

gttactatga atgcgcatta cttttctaat aaaatgtttc tgaatctc                4068


<210>  7903
<211>  273
<212>  PRT
<213>  Homo sapiens

<400>  7903

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Tyr Pro Asp Met Pro Thr Ala Ala 
        195                 200                 205


Asp Val Val Asn Ala Leu Asp Gln Gln Ala Leu Ala Ser Ile Leu Arg 
    210                 215                 220


Thr Tyr Gly Glu Glu Lys His Ala Lys Lys Ile Ala Ser Ala Ile Val 
225                 230                 235                 240


Gln Ala Arg Ser Ile Tyr Pro Ile Thr Arg Thr Gln Gln Leu Ala Ser 
                245                 250                 255


Ile Val Ala Glu Tyr Ser Glu Thr Tyr Phe Pro Val Ala Gln Thr Leu 
            260                 265                 270


Tyr 



<210>  7904
<211>  4177
<212>  DNA
<213>  Homo sapiens

<400>  7904
ctagacgcgc ggcgcattca ggttctcctg gaccgtagtg gtagtcgctg gcccgagtta     60

gaggccagct gagaagtctt cgtgcttcag atttgtttac ctacaaaatg cttcggtatc    120

catatttttg tagaatgtat aaagaatgcc tttcatgttg gttggaatct ggcataccta    180

atttaggtgt ctggccaaac agaatacata ctacagcaga aaaatataga gaatatgaag    240

cccgggagca aacagatcaa actcaagccc aggagttaca cagatctcaa gatagagatt    300

ttgaaactat ggctaaatta catattccag taatggtgga tgaagttgtt cattgtttgt    360

caccacaaaa aggacagatt tttctagata tgacatttgg ttcgggaggg cacacaaaag    420

ccattctgca gaaggagtca gatattgttc tctatgcctt ggacagagac ccaacagctt    480

atgcattagc tgaacatctt tcagagttgt atcctaaaca aatccgagct atgctgggcc    540

agttcagcca ggcagaagcc ttattaatga aagctggagt gcagccagga acttttgatg    600

gagttcttat ggatcttggg tgttcctcca tgcaacttga tactcctgaa agaggttttt    660

cccttcggaa agatggccct ttggacatga gaatggatgg tggcaggtac cctgacatgc    720

ccactgctgc tgatgttgtg aatgctttag atcaacaggc acttgcatct atcctaagaa    780

catacgggga ggagaagcat gccaagaaaa tcgcttcagc aattgttcag gcacgcagca    840

tctaccccat caccagaacc cagcagcttg ccagcatcgt tgcagaatac tctgaaacat    900

atttcccagt ggcccaaact ctttattagg aaaatggacg aattgaatag caaatggagc    960

atttcctccc tctgctattt atacacggaa agacttacta cagcgatcta cccatattgc   1020

caccaagact ttccaggctc ttcgcatatt tgtgaacaat gagctcaatg aactctacac   1080

gggactgaag acagctcaga agtttctgag acctggtggt cgtcttgttg ccctctcctt   1140

ccattcacta gaggatcgca tcgtcaaaag atttttgctt ggaataagca tgacagaaag   1200

atttaaccta agtgttagac aacaagtgat gaaaacatct caattgggtt cagatcacga   1260

aaacacggaa gaagtctcta tgagaagagc tcctttaatg tgggaattga tacacaagaa   1320

ggtacttagt ccacaagatc aggatgtaca agataacccc agagggcgct cagccaagct   1380

tagagcagct atcaaattat aagttatcat catcttattc ttcaaatttt tttctcacaa   1440

tttctctaat ctttactcat gttatgtccc tgaatgtctt ggtataggtt taagtgtggg   1500

acagtctgaa aattgatagc atttagcatt tcttttttct caaaaagaaa ctgtaggaaa   1560

tacatgacag agaaagttac actcagggag cagcagcacc tccagactgg aaaaatatgt   1620

taatctttgc atcatattgg actcttgaag gcaatccttc ctctggccag gaaatttttt   1680

aaaaaataat actgtgttgt gtttatctaa atacgtaaac tcaagctacc aaagagaaag   1740

atgttgtaat catatctgca tgtcctaaat tttgaattta gatattccaa tttgcatcag   1800

tctttctgtg gctcaaataa tgatgattat ggaatgaatt ttaatgtccc tacttgtgaa   1860

taattagctt tctcaaatgt aggcttttta caaattttaa attttaaaat attagtttaa   1920

atgtgtgtta tactgataaa atttcatctt tcaaattata gtctattatt ttaaagggat   1980

ttttcagtat gatatgggcc attttgttca tctatcgcaa agtaaaaatg taaaatcctt   2040

acagagaatt gtttcacaaa acttatattt catgtcaatt gtatttattt taataatagc   2100

tcacaatgcc tttagtaagt aataaagtct cttattagaa tcttgtattt tttaattgag   2160

ctaatcaaaa taattcagcc aagtctattt gaaatagaaa actgtctatt taatatagta   2220

aaatcaatgc tcccttaatg ttgttacaaa gatatggtaa ctgtaatatg ggtaaaagtt   2280

tattcaagaa aagagtactt ggtagaagat tctttaacaa attgaggaga ttgattcata   2340

attcacatgt caatttttta tagtaatatg tacttctaat ttattattta tacttaaatt   2400

gtgacctgaa agatgagttg gagataatta gtcaaagggc acatggagta tggaaggggg   2460

catgttgatt aaccatacat agaaataaat attctcttag ttatccttga aatcatattt   2520

atactattaa tttgctcagt gcactttttt caaatacaga aaaaagattc tccattatag   2580

ttacaaattt taggttggtg aatccaagtg aatgaaatat cagcataact atgtgggcaa   2640

aatagataga attaaatgca tgaattttcc tcagacttat tttatctgcc tctgtaatat   2700

ttaactttag tacccaggct tgttcactac ttctgcttta caggctttat ttaaatctga   2760

acaatcctac agggaaatca gaattaggaa aaaaatctgg agaacaatat ggttgaaata   2820

gaaacaagag aatgcaccta ggttaattcc ctgaatccta cttgaacatt gtataaattt   2880

ctctttgcat ataatacata tttgtgaatg agacatattc ccaaaaaatt cttatctctg   2940

tatgtgattg gaaaagaaaa gatcacattt gtatattcaa caatctttca cctatttcat   3000

aagtcatttt ttcaccctgt atagtatggg aattattttt tatgttaaat agaaactgaa   3060

tgtactgggt tgaatggtgt cctctccaaa attcatgtac ttcctggagc ctcagtatgt   3120

gaccttattt ggaaatactg tggttgtggt tgtaagtagc taagatgagg tcatactgga   3180

gcagggcagg cccttaatcc aatatgactg gtgttcctta taagagaaga tagggcgggc   3240

atggtggctc acgcctgtaa tcccagcact gtgggaggcc aagccaggca aatcgcttga   3300

ggctgaggag ttcaagacca gcctggccaa catggcgaaa acccatctct actaaaaata   3360

aaattagcca tgcgtggtgc ttgtaatgtc agctacccag gagtctgagg cacaagaatc   3420

actcgaacct gggaggtgga ggttgcgaga tcacaccact gcactccagt gtgagcaaca   3480

gaacgagact ctgtctcaaa aaaaaaaaaa aaaaggaaga aagagaagat agagacacag   3540

gggagaatgc cacatgaagc tggaggcaga gattggagtg atacattgtg ggaaccctca   3600

gaagatagga aaaaagcatg gaatagattc tccctcagag ttccagtagt tgccaaccct   3660

gctaacatgg ttttgcacat ctagcatcca gaacagtgag aatgtatttc tgctgtttta   3720

aggtacccag ttcatggtaa tttgttacag caatcctagg aagctaatac tctgacagaa   3780

aaaaatcttg gataatatgc atgagaaaaa tccttcaata aacacaaaat tggtttcaaa   3840

atgttttcat gtaaaaataa attaactttt ctgtaattag attgtgtttt atagtaattc   3900

ttgcctgctt cttagtcttt gttgtaggat gcataataaa atacatgaat gagttttaaa   3960

tggttagctt tggagaatgg ttttgggaag ttcctacagt acacagaaat aaaagctaat   4020

gttactatga atgcgcatta cttttctaat aaaatgtttc tgaatctctg tcttgactgc   4080

cttctatgaa tcattttaac atagtatcaa tgtcattgtg tagtacatca gttcttaaca   4140

gtttttagtt cattacttaa ataaaattta ataacta                            4177


<210>  7905
<211>  273
<212>  PRT
<213>  Homo sapiens

<400>  7905

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Tyr Pro Asp Met Pro Thr Ala Ala 
        195                 200                 205


Asp Val Val Asn Ala Leu Asp Gln Gln Ala Leu Ala Ser Ile Leu Arg 
    210                 215                 220


Thr Tyr Gly Glu Glu Lys His Ala Lys Lys Ile Ala Ser Ala Ile Val 
225                 230                 235                 240


Gln Ala Arg Ser Ile Tyr Pro Ile Thr Arg Thr Gln Gln Leu Ala Ser 
                245                 250                 255


Ile Val Ala Glu Tyr Ser Glu Thr Tyr Phe Pro Val Ala Gln Thr Leu 
            260                 265                 270


Tyr 



<210>  7906
<211>  3995
<212>  DNA
<213>  Homo sapiens

<400>  7906
agacgcgcgg cgcattcagg ttctcctgga ccgtagtggt agtcgctggc ccgagttaga     60

ggccagctga gaagtcttcg tgcttcagat ttgtttacct acaaaatgct tcggtatcca    120

tatttttgta gaatgtataa agaatgcctt tcatgttggt tggaatctgg catacctaat    180

ttaggtgtct ggccaaacag aatacatact acagcagaaa aatatagaga atatgaagcc    240

cgggagcaaa cagatcaaac tcaagcccag gagttacaca gatctcaaga tagagatttt    300

gaaactatgg ctaaattaca tattccagta atggtggatg aagttgttca ttgtttgtca    360

ccacaaaaag gacagatttt tctagatatg acatttggtt cgggagggca cacaaaagcc    420

attctgcaga aggagtcaga tattgttctc tatgccttgg acagagaccc aacagcttat    480

gcattagctg aacatctttc agagttgtat cctaaacaaa tccgagctat gctgggccag    540

ttcagccagg cagaagcctt attaatgaaa gctggagtgc agccaggaac ttttgatgga    600

gttcttatgg atcttgggtg ttcctccatg caacttgata ctcctgaaag aggtttttcc    660

cttcggaaag atggcccttt ggacatgaga atggatggtg gcaggtaccc tgacatgccc    720

actgctgctg atgttgtgaa tgctttagat caacaggcac ttgcatctat cctaagaaca    780

tacggggagg agaagcatgc caagaaaatc gcttcagcaa ttgttcaggc acgcagcatc    840

taccccatca ccagaaccca gcagcttgcc agcatcgttg caggagcatt tcctccctct    900

gctatttata cacggaaaga cttactacag cgatctaccc atattgccac caagactttc    960

caggctcttc gcatatttgt gaacaatgag ctcaatgaac tctacacggg actgaagaca   1020

gctcagaagt ttctgagacc tggtggtcgt cttgttgccc tctccttcca ttcactagag   1080

gatcgcatcg tcaaaagatt tttgcttgga ataagcatga cagaaagatt taacctaagt   1140

gttagacaac aagtgatgaa aacatctcaa ttgggttcag atcacgaaaa cacggaagaa   1200

gtctctatga gaagagctcc tttaatgtgg gaattgatac acaagaaggt acttagtcca   1260

caagatcagg atgtacaaga taaccccaga gggcgctcag ccaagcttag agcagctatc   1320

aaattataag ttatcatcat cttattcttc aaattttttt ctcacaattt ctctaatctt   1380

tactcatgtt atgtccctga atgtcttggt ataggtttaa gtgtgggaca gtctgaaaat   1440

tgatagcatt tagcatttct tttttctcaa aaagaaactg taggaaatac atgacagaga   1500

aagttacact cagggagcag cagcacctcc agactggaaa aatatgttaa tctttgcatc   1560

atattggact cttgaaggca atccttcctc tggccaggaa attttttaaa aaataatact   1620

gtgttgtgtt tatctaaata cgtaaactca agctaccaaa gagaaagatg ttgtaatcat   1680

atctgcatgt cctaaatttt gaatttagat attccaattt gcatcagtct ttctgtggct   1740

caaataatga tgattatgga atgaatttta atgtccctac ttgtgaataa ttagctttct   1800

caaatgtagg ctttttacaa attttaaatt ttaaaatatt agtttaaatg tgtgttatac   1860

tgataaaatt tcatctttca aattatagtc tattatttta aagggatttt tcagtatgat   1920

atgggccatt ttgttcatct atcgcaaagt aaaaatgtaa aatccttaca gagaattgtt   1980

tcacaaaact tatatttcat gtcaattgta tttattttaa taatagctca caatgccttt   2040

agtaagtaat aaagtctctt attagaatct tgtatttttt aattgagcta atcaaaataa   2100

ttcagccaag tctatttgaa atagaaaact gtctatttaa tatagtaaaa tcaatgctcc   2160

cttaatgttg ttacaaagat atggtaactg taatatgggt aaaagtttat tcaagaaaag   2220

agtacttggt agaagattct ttaacaaatt gaggagattg attcataatt cacatgtcaa   2280

ttttttatag taatatgtac ttctaattta ttatttatac ttaaattgtg acctgaaaga   2340

tgagttggag ataattagtc aaagggcaca tggagtatgg aagggggcat gttgattaac   2400

catacataga aataaatatt ctcttagtta tccttgaaat catatttata ctattaattt   2460

gctcagtgca cttttttcaa atacagaaaa aagattctcc attatagtta caaattttag   2520

gttggtgaat ccaagtgaat gaaatatcag cataactatg tgggcaaaat agatagaatt   2580

aaatgcatga attttcctca gacttatttt atctgcctct gtaatattta actttagtac   2640

ccaggcttgt tcactacttc tgctttacag gctttattta aatctgaaca atcctacagg   2700

gaaatcagaa ttaggaaaaa aatctggaga acaatatggt tgaaatagaa acaagagaat   2760

gcacctaggt taattccctg aatcctactt gaacattgta taaatttctc tttgcatata   2820

atacatattt gtgaatgaga catattccca aaaaattctt atctctgtat gtgattggaa   2880

aagaaaagat cacatttgta tattcaacaa tctttcacct atttcataag tcattttttc   2940

accctgtata gtatgggaat tattttttat gttaaataga aactgaatgt actgggttga   3000

atggtgtcct ctccaaaatt catgtacttc ctggagcctc agtatgtgac cttatttgga   3060

aatactgtgg ttgtggttgt aagtagctaa gatgaggtca tactggagca gggcaggccc   3120

ttaatccaat atgactggtg ttccttataa gagaagatag ggcgggcatg gtggctcacg   3180

cctgtaatcc cagcactgtg ggaggccaag ccaggcaaat cgcttgaggc tgaggagttc   3240

aagaccagcc tggccaacat ggcgaaaacc catctctact aaaaataaaa ttagccatgc   3300

gtggtgcttg taatgtcagc tacccaggag tctgaggcac aagaatcact cgaacctggg   3360

aggtggaggt tgcgagatca caccactgca ctccagtgtg agcaacagaa cgagactctg   3420

tctcaaaaaa aaaaaaaaaa aggaagaaag agaagataga gacacagggg agaatgccac   3480

atgaagctgg aggcagagat tggagtgata cattgtggga accctcagaa gataggaaaa   3540

aagcatggaa tagattctcc ctcagagttc cagtagttgc caaccctgct aacatggttt   3600

tgcacatcta gcatccagaa cagtgagaat gtatttctgc tgttttaagg tacccagttc   3660

atggtaattt gttacagcaa tcctaggaag ctaatactct gacagaaaaa aatcttggat   3720

aatatgcatg agaaaaatcc ttcaataaac acaaaattgg tttcaaaatg ttttcatgta   3780

aaaataaatt aacttttctg taattagatt gtgttttata gtaattcttg cctgcttctt   3840

agtctttgtt gtaggatgca taataaaata catgaatgag ttttaaatgg ttagctttgg   3900

agaatggttt tgggaagttc ctacagtaca cagaaataaa agctaatgtt actatgaatg   3960

cgcattactt ttctaataaa atgtttctga atctc                              3995


<210>  7907
<211>  407
<212>  PRT
<213>  Homo sapiens

<400>  7907

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Tyr Pro Asp Met Pro Thr Ala Ala 
        195                 200                 205


Asp Val Val Asn Ala Leu Asp Gln Gln Ala Leu Ala Ser Ile Leu Arg 
    210                 215                 220


Thr Tyr Gly Glu Glu Lys His Ala Lys Lys Ile Ala Ser Ala Ile Val 
225                 230                 235                 240


Gln Ala Arg Ser Ile Tyr Pro Ile Thr Arg Thr Gln Gln Leu Ala Ser 
                245                 250                 255


Ile Val Ala Gly Ala Phe Pro Pro Ser Ala Ile Tyr Thr Arg Lys Asp 
            260                 265                 270


Leu Leu Gln Arg Ser Thr His Ile Ala Thr Lys Thr Phe Gln Ala Leu 
        275                 280                 285


Arg Ile Phe Val Asn Asn Glu Leu Asn Glu Leu Tyr Thr Gly Leu Lys 
    290                 295                 300


Thr Ala Gln Lys Phe Leu Arg Pro Gly Gly Arg Leu Val Ala Leu Ser 
305                 310                 315                 320


Phe His Ser Leu Glu Asp Arg Ile Val Lys Arg Phe Leu Leu Gly Ile 
                325                 330                 335


Ser Met Thr Glu Arg Phe Asn Leu Ser Val Arg Gln Gln Val Met Lys 
            340                 345                 350


Thr Ser Gln Leu Gly Ser Asp His Glu Asn Thr Glu Glu Val Ser Met 
        355                 360                 365


Arg Arg Ala Pro Leu Met Trp Glu Leu Ile His Lys Lys Val Leu Ser 
    370                 375                 380


Pro Gln Asp Gln Asp Val Gln Asp Asn Pro Arg Gly Arg Ser Ala Lys 
385                 390                 395                 400


Leu Arg Ala Ala Ile Lys Leu 
                405


<210>  7908
<211>  4104
<212>  DNA
<213>  Homo sapiens

<400>  7908
agacgcgcgg cgcattcagg ttctcctgga ccgtagtggt agtcgctggc ccgagttaga     60

ggccagctga gaagtcttcg tgcttcagat ttgtttacct acaaaatgct tcggtatcca    120

tatttttgta gaatgtataa agaatgcctt tcatgttggt tggaatctgg catacctaat    180

ttaggtgtct ggccaaacag aatacatact acagcagaaa aatatagaga atatgaagcc    240

cgggagcaaa cagatcaaac tcaagcccag gagttacaca gatctcaaga tagagatttt    300

gaaactatgg ctaaattaca tattccagta atggtggatg aagttgttca ttgtttgtca    360

ccacaaaaag gacagatttt tctagatatg acatttggtt cgggagggca cacaaaagcc    420

attctgcaga aggagtcaga tattgttctc tatgccttgg acagagaccc aacagcttat    480

gcattagctg aacatctttc agagttgtat cctaaacaaa tccgagctat gctgggccag    540

ttcagccagg cagaagcctt attaatgaaa gctggagtgc agccaggaac ttttgatgga    600

gttcttatgg atcttgggtg ttcctccatg caacttgata ctcctgaaag aggtttttcc    660

cttcggaaag atggcccttt ggacatgaga atggatggtg gcaggtaccc tgacatgccc    720

actgctgctg atgttgtgaa tgctttagat caacaggcac ttgcatctat cctaagaaca    780

tacggggagg agaagcatgc caagaaaatc gcttcagcaa ttgttcaggc acgcagcatc    840

taccccatca ccagaaccca gcagcttgcc agcatcgttg caggagcatt tcctccctct    900

gctatttata cacggaaaga cttactacag cgatctaccc atattgccac caagactttc    960

caggctcttc gcatatttgt gaacaatgag ctcaatgaac tctacacggg actgaagaca   1020

gctcagaagt ttctgagacc tggtggtcgt cttgttgccc tctccttcca ttcactagag   1080

gatcgcatcg tcaaaagatt tttgcttgga ataagcatga cagaaagatt taacctaagt   1140

gttagacaac aagtgatgaa aacatctcaa ttgggttcag atcacgaaaa cacggaagaa   1200

gtctctatga gaagagctcc tttaatgtgg gaattgatac acaagaaggt acttagtcca   1260

caagatcagg atgtacaaga taaccccaga gggcgctcag ccaagcttag agcagctatc   1320

aaattataag ttatcatcat cttattcttc aaattttttt ctcacaattt ctctaatctt   1380

tactcatgtt atgtccctga atgtcttggt ataggtttaa gtgtgggaca gtctgaaaat   1440

tgatagcatt tagcatttct tttttctcaa aaagaaactg taggaaatac atgacagaga   1500

aagttacact cagggagcag cagcacctcc agactggaaa aatatgttaa tctttgcatc   1560

atattggact cttgaaggca atccttcctc tggccaggaa attttttaaa aaataatact   1620

gtgttgtgtt tatctaaata cgtaaactca agctaccaaa gagaaagatg ttgtaatcat   1680

atctgcatgt cctaaatttt gaatttagat attccaattt gcatcagtct ttctgtggct   1740

caaataatga tgattatgga atgaatttta atgtccctac ttgtgaataa ttagctttct   1800

caaatgtagg ctttttacaa attttaaatt ttaaaatatt agtttaaatg tgtgttatac   1860

tgataaaatt tcatctttca aattatagtc tattatttta aagggatttt tcagtatgat   1920

atgggccatt ttgttcatct atcgcaaagt aaaaatgtaa aatccttaca gagaattgtt   1980

tcacaaaact tatatttcat gtcaattgta tttattttaa taatagctca caatgccttt   2040

agtaagtaat aaagtctctt attagaatct tgtatttttt aattgagcta atcaaaataa   2100

ttcagccaag tctatttgaa atagaaaact gtctatttaa tatagtaaaa tcaatgctcc   2160

cttaatgttg ttacaaagat atggtaactg taatatgggt aaaagtttat tcaagaaaag   2220

agtacttggt agaagattct ttaacaaatt gaggagattg attcataatt cacatgtcaa   2280

ttttttatag taatatgtac ttctaattta ttatttatac ttaaattgtg acctgaaaga   2340

tgagttggag ataattagtc aaagggcaca tggagtatgg aagggggcat gttgattaac   2400

catacataga aataaatatt ctcttagtta tccttgaaat catatttata ctattaattt   2460

gctcagtgca cttttttcaa atacagaaaa aagattctcc attatagtta caaattttag   2520

gttggtgaat ccaagtgaat gaaatatcag cataactatg tgggcaaaat agatagaatt   2580

aaatgcatga attttcctca gacttatttt atctgcctct gtaatattta actttagtac   2640

ccaggcttgt tcactacttc tgctttacag gctttattta aatctgaaca atcctacagg   2700

gaaatcagaa ttaggaaaaa aatctggaga acaatatggt tgaaatagaa acaagagaat   2760

gcacctaggt taattccctg aatcctactt gaacattgta taaatttctc tttgcatata   2820

atacatattt gtgaatgaga catattccca aaaaattctt atctctgtat gtgattggaa   2880

aagaaaagat cacatttgta tattcaacaa tctttcacct atttcataag tcattttttc   2940

accctgtata gtatgggaat tattttttat gttaaataga aactgaatgt actgggttga   3000

atggtgtcct ctccaaaatt catgtacttc ctggagcctc agtatgtgac cttatttgga   3060

aatactgtgg ttgtggttgt aagtagctaa gatgaggtca tactggagca gggcaggccc   3120

ttaatccaat atgactggtg ttccttataa gagaagatag ggcgggcatg gtggctcacg   3180

cctgtaatcc cagcactgtg ggaggccaag ccaggcaaat cgcttgaggc tgaggagttc   3240

aagaccagcc tggccaacat ggcgaaaacc catctctact aaaaataaaa ttagccatgc   3300

gtggtgcttg taatgtcagc tacccaggag tctgaggcac aagaatcact cgaacctggg   3360

aggtggaggt tgcgagatca caccactgca ctccagtgtg agcaacagaa cgagactctg   3420

tctcaaaaaa aaaaaaaaaa aggaagaaag agaagataga gacacagggg agaatgccac   3480

atgaagctgg aggcagagat tggagtgata cattgtggga accctcagaa gataggaaaa   3540

aagcatggaa tagattctcc ctcagagttc cagtagttgc caaccctgct aacatggttt   3600

tgcacatcta gcatccagaa cagtgagaat gtatttctgc tgttttaagg tacccagttc   3660

atggtaattt gttacagcaa tcctaggaag ctaatactct gacagaaaaa aatcttggat   3720

aatatgcatg agaaaaatcc ttcaataaac acaaaattgg tttcaaaatg ttttcatgta   3780

aaaataaatt aacttttctg taattagatt gtgttttata gtaattcttg cctgcttctt   3840

agtctttgtt gtaggatgca taataaaata catgaatgag ttttaaatgg ttagctttgg   3900

agaatggttt tgggaagttc ctacagtaca cagaaataaa agctaatgtt actatgaatg   3960

cgcattactt ttctaataaa atgtttctga atctctgtct tgactgcctt ctatgaatca   4020

ttttaacata gtatcaatgt cattgtgtag tacatcagtt cttaacagtt tttagttcat   4080

tacttaaata aaatttaata acta                                          4104


<210>  7909
<211>  407
<212>  PRT
<213>  Homo sapiens

<400>  7909

Met Leu Arg Tyr Pro Tyr Phe Cys Arg Met Tyr Lys Glu Cys Leu Ser 
1               5                   10                  15


Cys Trp Leu Glu Ser Gly Ile Pro Asn Leu Gly Val Trp Pro Asn Arg 
            20                  25                  30


Ile His Thr Thr Ala Glu Lys Tyr Arg Glu Tyr Glu Ala Arg Glu Gln 
        35                  40                  45


Thr Asp Gln Thr Gln Ala Gln Glu Leu His Arg Ser Gln Asp Arg Asp 
    50                  55                  60


Phe Glu Thr Met Ala Lys Leu His Ile Pro Val Met Val Asp Glu Val 
65                  70                  75                  80


Val His Cys Leu Ser Pro Gln Lys Gly Gln Ile Phe Leu Asp Met Thr 
                85                  90                  95


Phe Gly Ser Gly Gly His Thr Lys Ala Ile Leu Gln Lys Glu Ser Asp 
            100                 105                 110


Ile Val Leu Tyr Ala Leu Asp Arg Asp Pro Thr Ala Tyr Ala Leu Ala 
        115                 120                 125


Glu His Leu Ser Glu Leu Tyr Pro Lys Gln Ile Arg Ala Met Leu Gly 
    130                 135                 140


Gln Phe Ser Gln Ala Glu Ala Leu Leu Met Lys Ala Gly Val Gln Pro 
145                 150                 155                 160


Gly Thr Phe Asp Gly Val Leu Met Asp Leu Gly Cys Ser Ser Met Gln 
                165                 170                 175


Leu Asp Thr Pro Glu Arg Gly Phe Ser Leu Arg Lys Asp Gly Pro Leu 
            180                 185                 190


Asp Met Arg Met Asp Gly Gly Arg Tyr Pro Asp Met Pro Thr Ala Ala 
        195                 200                 205


Asp Val Val Asn Ala Leu Asp Gln Gln Ala Leu Ala Ser Ile Leu Arg 
    210                 215                 220


Thr Tyr Gly Glu Glu Lys His Ala Lys Lys Ile Ala Ser Ala Ile Val 
225                 230                 235                 240


Gln Ala Arg Ser Ile Tyr Pro Ile Thr Arg Thr Gln Gln Leu Ala Ser 
                245                 250                 255


Ile Val Ala Gly Ala Phe Pro Pro Ser Ala Ile Tyr Thr Arg Lys Asp 
            260                 265                 270


Leu Leu Gln Arg Ser Thr His Ile Ala Thr Lys Thr Phe Gln Ala Leu 
        275                 280                 285


Arg Ile Phe Val Asn Asn Glu Leu Asn Glu Leu Tyr Thr Gly Leu Lys 
    290                 295                 300


Thr Ala Gln Lys Phe Leu Arg Pro Gly Gly Arg Leu Val Ala Leu Ser 
305                 310                 315                 320


Phe His Ser Leu Glu Asp Arg Ile Val Lys Arg Phe Leu Leu Gly Ile 
                325                 330                 335


Ser Met Thr Glu Arg Phe Asn Leu Ser Val Arg Gln Gln Val Met Lys 
            340                 345                 350


Thr Ser Gln Leu Gly Ser Asp His Glu Asn Thr Glu Glu Val Ser Met 
        355                 360                 365


Arg Arg Ala Pro Leu Met Trp Glu Leu Ile His Lys Lys Val Leu Ser 
    370                 375                 380


Pro Gln Asp Gln Asp Val Gln Asp Asn Pro Arg Gly Arg Ser Ala Lys 
385                 390                 395                 400


Leu Arg Ala Ala Ile Lys Leu 
                405


<210>  7910
<211>  1768
<212>  DNA
<213>  Homo sapiens

<400>  7910
catcaaatga aaggaattag gaatctcatc gtttgacagc tagctaacta aatgaattat     60

aaattatgtc catccttctg ccacaggaag gtgctatttt agctagtaag ccaaaatgtc    120

taacaaactt taatgtcaaa taaaccaatg ctgttgttta tattagaact acatggttat    180

ttcagatact attttgttat ttttttggtt ttgttatgaa acattccatt ttcattaatt    240

ttacaaaaca catttactga aaatagtatg caaacattta ttgagctttc tgcctttcta    300

ttttatgaat taagagattc tgcattaaaa tgtcaataaa gttaagcagt tatgttgaac    360

catcatttta atttctgcaa aatatcaaag ataatgctaa gaaattttta aaaaaattat    420

agcaaaaata tcctgcagtt cttattgatt tatgtgctcc atgaatgttt acttcctatt    480

ttacatgaaa atatatgttt gttcatattc ttagaatact ctgaaacata tttcccagtg    540

gcccaaactc tttattagga aaatggacga attgaatagc aaatggagca tttcctccct    600

ctgctattta tacacggaaa gacttactac agcgatctac ccatattgcc accaagactt    660

tccaggctct tcgcatattt gtgaacaatg agctcaatga actctacacg ggactgaaga    720

cagctcagaa gtttctgaga cctggtggtc gtcttgttgc cctctccttc cattcactag    780

aggatcgcat cgtcaaaaga tttttgcttg gaataagcat gacagaaaga tttaacctaa    840

gtgttagaca acaagtgatg aaaacatctc aattgggttc agatcacgaa aacacggaag    900

aagtctctat gagaagagct cctttaatgt gggaattgat acacaagaag gtacttagtc    960

cacaagatca ggatgtacaa gataacccca gagggcgctc agccaagctt agagcagcta   1020

tcaaattata agttatcatc atcttattct tcaaattttt ttctcacaat ttctctaatc   1080

tttactcatg ttatgtccct gaatgtcttg gtataggttt aagtgtggga cagtctgaaa   1140

attgatagca tttagcattt cttttttctc aaaaagaaac tgtaggaaat acatgacaga   1200

gaaagttaca ctcagggagc agcagcacct ccagactgga aaaatatgtt aatctttgca   1260

tcatattgga ctcttgaagg caatccttcc tctggccagg aaatttttta aaaaataata   1320

ctgtgttgtg tttatctaaa tacgtaaact caagctacca aagagaaaga tgttgtaatc   1380

atatctgcat gtcctaaatt ttgaatttag atattccaat ttgcatcagt ctttctgtgg   1440

ctcaaataat gatgattatg gaatgaattt taatgtccct acttgtgaat aattagcttt   1500

ctcaaatgta ggctttttac aaattttaaa ttttaaaata ttagtttaaa tgtgtgttat   1560

actgataaaa tttcatcttt caaattatag tctattattt taaagggatt tttcagtatg   1620

atatgggcca ttttgttcat ctatcgcaaa gtaaaaatgt aaaatcctta cagagaattg   1680

tttcacaaaa cttatatttc atgtcaattg tatttatttt aataatagct cacaatgcct   1740

ttagtaagta ataaagtctc ttattaga                                      1768


<210>  7911
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  7911

Met Asp Glu Leu Asn Ser Lys Trp Ser Ile Ser Ser Leu Cys Tyr Leu 
1               5                   10                  15


Tyr Thr Glu Arg Leu Thr Thr Ala Ile Tyr Pro Tyr Cys His Gln Asp 
            20                  25                  30


Phe Pro Gly Ser Ser His Ile Cys Glu Gln 
        35                  40


<210>  7912
<211>  505
<212>  DNA
<213>  Homo sapiens

<400>  7912
aggagcgcta agtgaacaag gatgctacat gcaggatcca cttgtgtcca ttgatctctc     60

agagtggctg aggatcatag gtttcttctt gaagggctca aggaatgaag catcccacaa    120

aatgatcctg ctgaataatt gccagatgct gctggccctg tacgaatccc tggccgtgag    180

cattcctgag tccctgaagg tcttcaagaa agtttaggtg aggggataag agcagctgca    240

ttttcaaagt cagtgaaggt agagcattca agagcattcc tctgtattat ggaagatatc    300

ctgaagctca atgcctgcaa taaaagcaag cttggaagta gggatgagat aggccaccca    360

gatgatgaat ttgagaggta caaaaacagg tgcttatcat ttataattgc tattccttgt    420

acttttttgt aattcacatt aatcagtttt ggaataaaga gaggatgaat tcctttcttg    480

tgatgaataa aggttgtcaa tggtc                                          505


<210>  7913
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  7913

Met Gln Asp Pro Leu Val Ser Ile Asp Leu Ser Glu Trp Leu Arg Ile 
1               5                   10                  15


Ile Gly Phe Phe Leu Lys Gly Ser Arg Asn Glu Ala Ser His Lys Met 
            20                  25                  30


Ile Leu Leu Asn Asn Cys Gln Met Leu Leu Ala Leu Tyr Glu Ser Leu 
        35                  40                  45


Ala Val Ser Ile Pro Glu Ser Leu Lys Val Phe Lys Lys Val 
    50                  55                  60


<210>  7914
<211>  564
<212>  DNA
<213>  Homo sapiens

<400>  7914
atcagcggca gaagggcagc aatggccaca caccgaagca ccttggcggg ctattcccct     60

tgcagctctc ctcagcgcgc tgctcccact cgcaatcaaa aggcggaaaa agcgcgaaac    120

cgccaggcat ctcccatacc cacccggctg ccgcgcaacc cctccttggc ttccactggg    180

agacagggga cgccgatgag caggaagaag cagggcagtg actgcttagt ttatcctggt    240

cacccgccag gtttgtggcc tgtgatctct tgtcaccttg gtctctcagc tttgtcttct    300

gaaatctgga cttccaattg tctttgtctt gctgcccttc cttgcgacac tggcctggaa    360

tccctcacgg tagtctgctg gagtggaatt taggacgcat ctcagttgtc accatcttta    420

attgcatgat gtctagttcc ttgcaaacca ttatttcatg tatttcgctc ttttttgttt    480

gttttgtttt gttttgtttt caggctaggg gaaaatccag tccctgttac tccattttgg    540

ccagaaattc aaggtaatga cttt                                           564


<210>  7915
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  7915

Met Ala Thr His Arg Ser Thr Leu Ala Gly Tyr Ser Pro Cys Ser Ser 
1               5                   10                  15


Pro Gln Arg Ala Ala Pro Thr Arg Asn Gln Lys Ala Glu Lys Ala Arg 
            20                  25                  30


Asn Arg Gln Ala Ser Pro Ile Pro Thr Arg Leu Pro Arg Asn Pro Ser 
        35                  40                  45


Leu Ala Ser Thr Gly Arg Gln Gly Thr Pro Met Ser Arg Lys Lys Gln 
    50                  55                  60


Gly Ser Asp Cys Leu Val Tyr Pro Gly His Pro Pro Gly Leu Trp Pro 
65                  70                  75                  80


Val Ile Ser Cys His Leu Gly Leu Ser Ala Leu Ser Ser Glu Ile Trp 
                85                  90                  95


Thr Ser Asn Cys Leu Cys Leu Ala Ala Leu Pro Cys Asp Thr Gly Leu 
            100                 105                 110


Glu Ser Leu Thr Val Val Cys Trp Ser Gly Ile 
        115                 120


<210>  7916
<211>  643
<212>  DNA
<213>  Homo sapiens

<400>  7916
agtgacaaac ctcttttggt ttacaggcgg tcagacactc agcatgactg gcaaaacaga     60

ttatctgtgt gtcagtgtac attttattca tccgtcgttt gggtcagggt ctgcgggcag    120

acacaggtag ctactgccct gttgtgagaa gcaatacctc aattggtgcc ccatgtgagg    180

agagctgtgt gaggacagtc aggggtctgc agaaacagac cttccgcagt tggagcccct    240

tgtaaggcaa gctatgaagg aagtgtaagg accgctttca tgaggaaagc tgcaaaggaa    300

gcctgaggaa tgcgacgggc ccccaggaaa caaaggtgaa gaaaaaccgc gtggtcaagt    360

cagtgagtaa ctacaatcaa agacagcctt gcagagcccc aggggagtca aggggaggag    420

caggctggca aggagagaga tgccccaggt ctgaaggagt gatgtagaag acaggatctg    480

ttggctggga acctaaggat gattcacact cacttcctag aactgaatca aaaggaaaat    540

cccacctctc cacaatcaag taacaaaagg atcagaggct actccttttg caaatcatgc    600

caccaattcc cactttccac tgcattgcag atgaaaaacg gaa                      643


<210>  7917
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  7917

Met Ile His Thr His Phe Leu Glu Leu Asn Gln Lys Glu Asn Pro Thr 
1               5                   10                  15


Ser Pro Gln Ser Ser Asn Lys Arg Ile Arg Gly Tyr Ser Phe Cys Lys 
            20                  25                  30


Ser Cys His Gln Phe Pro Leu Ser Thr Ala Leu Gln Met Lys Asn 
        35                  40                  45


<210>  7918
<211>  1599
<212>  DNA
<213>  Homo sapiens

<400>  7918
cctttaggta tctgatcgct ttgccaattt tgcgttactg ggcaggctaa gagatcttct     60

tttaattcag cctgcttaag acgggaactg ataactgtag tgtatcctct gccttttttc    120

ttatctattg gaggaagctc agatggtgtc acaagaagga tctgaagtgg agcttctagt    180

atccccagga gcgcgaagtg aacacggaag gtacctgcag gatccaattg tgtccattga    240

tctctcagag tggctgagga taatagagtt tcttcttcaa ggtctcaagg tctgaagcat    300

cccacagaat gatcctactg aataactccc ataagctgct ggccctatac aaatccttgg    360

ccaggagcat ccctgagtcc ctgaaggtgt atggctctgt gtatcacatc aatcacggga    420

accccttcaa catggaggtg ctggtggatt cctggcctga atatcagatg gttattatcc    480

ggcctcaaaa gcaggagatg actgatgaca tggattcata cacaaacgta tatcgtatgt    540

tctccaaaga gcctcaaaaa tcagaagaag ttttgaaaaa ttgtgagatc gtaaactgga    600

aacagagact ccaaatccaa ggtcttcaag aaagtttagg tgaggggata agagtggcta    660

cattttcaaa gtcagtgaaa gtagagcatt cgagagcact cctcttggtt acggaagata    720

ttctgaagct caatgcctcc agtaaaagca agcttggaag ctgggctgag acaggccacc    780

cagatgatga atttgaaagt gaaactccca actttaagta tgcccagctg gatgtctctt    840

attctgggct ggtaaatgac aactggaagc gagggaagaa tgagaggagc ctgcattaca    900

tcaagcgctg catagaagac ctgccagcag cctgtatgct cggcccagag ggagtcccgg    960

tctcatgggt aaccatggac ccttcttgtg aagtaggaat ggcctacagc atggaaaaat   1020

accgaaggac aggcaacatg gcacgagtga tggtgcgata catgaaatat ctgcgtcaga   1080

agaatattcc attttacatc tctgtgttgg aagaaaatga agactcccgc agatttgtgg   1140

ggcagtttgg tttctttgag gcctcctgtg agtggcacca atggacttgc tacccacaga   1200

atctagttcc attttagaca atgaagctgc ttagtaatct ctgccaagcc atctcttaat   1260

attaaagcag acaccacaga atagatttct tcacttacaa atgcatattg ggcacttata   1320

atacagcagg aactcttctc acctggagcc ttgatgttaa aagacacagc catgctcttg   1380

aggagcttac aatcctggct ggaggcaggg gagggtatat tctttaaata tgcttaagtg   1440

ttatagggaa agacggggtt accagtaaac atgtaactag aaagccaggc tcagttctta   1500

cctctgggaa tcagaactct ttatgcaact tggttaatag aatctactat ctggaagata   1560

aatgaaggat tttaataaaa ttttcaatag aataaacct                          1599


<210>  7919
<211>  302
<212>  PRT
<213>  Homo sapiens

<400>  7919

Met Ile Leu Leu Asn Asn Ser His Lys Leu Leu Ala Leu Tyr Lys Ser 
1               5                   10                  15


Leu Ala Arg Ser Ile Pro Glu Ser Leu Lys Val Tyr Gly Ser Val Tyr 
            20                  25                  30


His Ile Asn His Gly Asn Pro Phe Asn Met Glu Val Leu Val Asp Ser 
        35                  40                  45


Trp Pro Glu Tyr Gln Met Val Ile Ile Arg Pro Gln Lys Gln Glu Met 
    50                  55                  60


Thr Asp Asp Met Asp Ser Tyr Thr Asn Val Tyr Arg Met Phe Ser Lys 
65                  70                  75                  80


Glu Pro Gln Lys Ser Glu Glu Val Leu Lys Asn Cys Glu Ile Val Asn 
                85                  90                  95


Trp Lys Gln Arg Leu Gln Ile Gln Gly Leu Gln Glu Ser Leu Gly Glu 
            100                 105                 110


Gly Ile Arg Val Ala Thr Phe Ser Lys Ser Val Lys Val Glu His Ser 
        115                 120                 125


Arg Ala Leu Leu Leu Val Thr Glu Asp Ile Leu Lys Leu Asn Ala Ser 
    130                 135                 140


Ser Lys Ser Lys Leu Gly Ser Trp Ala Glu Thr Gly His Pro Asp Asp 
145                 150                 155                 160


Glu Phe Glu Ser Glu Thr Pro Asn Phe Lys Tyr Ala Gln Leu Asp Val 
                165                 170                 175


Ser Tyr Ser Gly Leu Val Asn Asp Asn Trp Lys Arg Gly Lys Asn Glu 
            180                 185                 190


Arg Ser Leu His Tyr Ile Lys Arg Cys Ile Glu Asp Leu Pro Ala Ala 
        195                 200                 205


Cys Met Leu Gly Pro Glu Gly Val Pro Val Ser Trp Val Thr Met Asp 
    210                 215                 220


Pro Ser Cys Glu Val Gly Met Ala Tyr Ser Met Glu Lys Tyr Arg Arg 
225                 230                 235                 240


Thr Gly Asn Met Ala Arg Val Met Val Arg Tyr Met Lys Tyr Leu Arg 
                245                 250                 255


Gln Lys Asn Ile Pro Phe Tyr Ile Ser Val Leu Glu Glu Asn Glu Asp 
            260                 265                 270


Ser Arg Arg Phe Val Gly Gln Phe Gly Phe Phe Glu Ala Ser Cys Glu 
        275                 280                 285


Trp His Gln Trp Thr Cys Tyr Pro Gln Asn Leu Val Pro Phe 
    290                 295                 300


<210>  7920
<211>  2264
<212>  DNA
<213>  Homo sapiens

<400>  7920
cctttaggta tctgatcgct ttgccaattt tgcgttactg ggcaggctaa gagatcttct     60

tttaattcag cctgcttaag acgggaactg ataactgtag tgtatcctct gccttttttc    120

ttatctattg gaggaagctc agatggtgtc acaagaagga tctgaagtgg agcttctagt    180

atccccagga gcgcgaagtg aacacggaag gtacctgcag gatccaattg tgtccattga    240

tctctcagag tggctgagga taatagagtt tcttcttcaa ggtctcaagg tctgaagcat    300

cccacagaat gatcctactg aataactccc ataagctgct ggccctatac aaatccttgg    360

ccaggagcat ccctgagtcc ctgaaggtgt atggctctgt gtatcacatc aatcacggga    420

accccttcaa catggaggtg ctggtggatt cctggcctga atatcagatg gttattatcc    480

ggcctcaaaa gcaggagatg actgatgaca tggattcata cacaaacgta tatcgtatgt    540

tctccaaaga gcctcaaaaa tcagaagaag ttttgaaaaa ttgtgagatc gtaaactgga    600

aacagagact ccaaatccaa ggtcttcaag aaagtttagg tgaggggata agagtggcta    660

cattttcaaa gtcagtgaaa gtagagcatt cgagagcact cctcttggtt acggaagata    720

ttctgaagct caatgcctcc agtaaaagca agcttggaag ctgggctgag acaggccacc    780

cagatgatga atttgaaagt gaaactccca actttaagta tgcccagctg gatgtctctt    840

attctgggct ggtaaatgac aactggaagc gagggaagaa tgagaggagc ctgcattaca    900

tcaagcgctg catagaagac ctgccagcag cctgtatgct cggcccagag ggagtcccgg    960

tctcatgggt aaccatggac ccttcttgtg aagtaggaat ggcctacagc atggaaaaat   1020

accgaaggac aggcaacatg gcacgagtga tggtgcgata catgaaatat ctgcgtcaga   1080

agaatattcc attttacatc tctgtgttgg aagaaaatga agactcccgc agatttgtgg   1140

ggcagtttgg tttctttgag gcctcctgtg agtggcacca atggacttgc tacccacaga   1200

atctagttcc attttagaca atgaagctgc ttagtaatct ctgccaagcc atctcttaat   1260

attaaagcag acaccacaga atagatttct tcacttacaa atgcatattg ggcacttata   1320

atacagcagg aactcttctc acctggagcc ttgatgttaa aagacacagc catgctcttg   1380

aggagcttac aatcctggct ggaggcaggg gagggtatat tctttaaata tgcttaagtg   1440

ttatagggaa agacggggtt accagtaaac atgtaactag aaagccaggc tcagttctta   1500

cctctgggaa tcagaactct ttatgcaact tggttaatag aatctactat ctggaagata   1560

aatgaaggat tttaataaaa ttttcaatag aataaaccta atctgtatgg atactttatc   1620

aaaaatgaat gtccctgcta tttctggatt tatgaggcaa tggtacacta aagaatggaa   1680

tcagttcagt gaatagaaag gtatccaagg tgaagcctga gacgaatggc tttcccaggc   1740

taccttccat cactgttgta cagaaaagaa atccagagaa tcaaatggac tggccttggg   1800

ggtctctgct atggaaatgc cattttttgt gtctcctttc tcctactctt tctcacatcc   1860

tcttcatgat tgaagcatgg cacaaggcaa ggtgttgcct gcgagtctgg ttgtaagttc   1920

agcctttggt gtttgcacta ctgctatcat aaggggtcag ggacattccg gggagaagtg   1980

accactaagg tgaggattag agagtgagta gaagtgagcc agacaaaaaa agcagaaaat   2040

gcagatgatg gaaaggacat gtgccatgca ctatcataag aacttcctaa ctgaacactg   2100

atactacaat tctgaatccc tgatcttaaa aaataattat acttcaccaa caaaacttgg   2160

cctcttttgg ttccactctg ccaccctgcc attggaactt ggattactgt gaacattgca   2220

gctatagcaa aataaaaaat aaaaaaaata aataattggc attt                    2264


<210>  7921
<211>  302
<212>  PRT
<213>  Homo sapiens

<400>  7921

Met Ile Leu Leu Asn Asn Ser His Lys Leu Leu Ala Leu Tyr Lys Ser 
1               5                   10                  15


Leu Ala Arg Ser Ile Pro Glu Ser Leu Lys Val Tyr Gly Ser Val Tyr 
            20                  25                  30


His Ile Asn His Gly Asn Pro Phe Asn Met Glu Val Leu Val Asp Ser 
        35                  40                  45


Trp Pro Glu Tyr Gln Met Val Ile Ile Arg Pro Gln Lys Gln Glu Met 
    50                  55                  60


Thr Asp Asp Met Asp Ser Tyr Thr Asn Val Tyr Arg Met Phe Ser Lys 
65                  70                  75                  80


Glu Pro Gln Lys Ser Glu Glu Val Leu Lys Asn Cys Glu Ile Val Asn 
                85                  90                  95


Trp Lys Gln Arg Leu Gln Ile Gln Gly Leu Gln Glu Ser Leu Gly Glu 
            100                 105                 110


Gly Ile Arg Val Ala Thr Phe Ser Lys Ser Val Lys Val Glu His Ser 
        115                 120                 125


Arg Ala Leu Leu Leu Val Thr Glu Asp Ile Leu Lys Leu Asn Ala Ser 
    130                 135                 140


Ser Lys Ser Lys Leu Gly Ser Trp Ala Glu Thr Gly His Pro Asp Asp 
145                 150                 155                 160


Glu Phe Glu Ser Glu Thr Pro Asn Phe Lys Tyr Ala Gln Leu Asp Val 
                165                 170                 175


Ser Tyr Ser Gly Leu Val Asn Asp Asn Trp Lys Arg Gly Lys Asn Glu 
            180                 185                 190


Arg Ser Leu His Tyr Ile Lys Arg Cys Ile Glu Asp Leu Pro Ala Ala 
        195                 200                 205


Cys Met Leu Gly Pro Glu Gly Val Pro Val Ser Trp Val Thr Met Asp 
    210                 215                 220


Pro Ser Cys Glu Val Gly Met Ala Tyr Ser Met Glu Lys Tyr Arg Arg 
225                 230                 235                 240


Thr Gly Asn Met Ala Arg Val Met Val Arg Tyr Met Lys Tyr Leu Arg 
                245                 250                 255


Gln Lys Asn Ile Pro Phe Tyr Ile Ser Val Leu Glu Glu Asn Glu Asp 
            260                 265                 270


Ser Arg Arg Phe Val Gly Gln Phe Gly Phe Phe Glu Ala Ser Cys Glu 
        275                 280                 285


Trp His Gln Trp Thr Cys Tyr Pro Gln Asn Leu Val Pro Phe 
    290                 295                 300


<210>  7922
<211>  1631
<212>  DNA
<213>  Homo sapiens

<400>  7922
gatcgctttg ccaattttgc gttactgggc aggctaagag atcttctttt aattcagcct     60

gcttaagacg ggaactgata actgtagtgt atcctctgcc ttttttctta tctattggag    120

gaagctcagg tgaagaaatg gagttgccat caactaagtt gagaaagact acagatggtg    180

tcacaagaag gatctgaagt ggagcttcta gtatccccag gagcgcgaag tgaacacgga    240

aggtacctgc aggatccaat tgtgtccatt gatctctcag agtggctgag gataatagag    300

tttcttcttc aaggtctcaa ggtctgaagc atcccacaga atgatcctac tgaataactc    360

ccataagctg ctggccctat acaaatcctt ggccaggagc atccctgagt ccctgaaggt    420

gtatggctct gtgtatcaca tcaatcacgg gaaccccttc aacatggagg tgctggtgga    480

ttcctggcct gaatatcaga tggttattat ccggcctcaa aagcaggaga tgactgatga    540

catggattca tacacaaacg tatatcgtat gttctccaaa gagcctcaaa aatcagaaga    600

agttttgaaa aattgtgaga tcgtaaactg gaaacagaga ctccaaatcc aaggtcttca    660

agaaagttta ggtgagggga taagagtggc tacattttca aagtcagtga aagtagagca    720

ttcgagagca ctcctcttgg ttacggaaga tattctgaag ctcaatgcct ccagtaaaag    780

caagcttgga agctgggctg agacaggcca cccagatgat gaatttgaaa gtgaaactcc    840

caactttaag tatgcccagc tggatgtctc ttattctggg ctggtaaatg acaactggaa    900

gcgagggaag aatgagagga gcctgcatta catcaagcgc tgcatagaag acctgccagc    960

agcctgtatg ctcggcccag agggagtccc ggtctcatgg gtaaccatgg acccttcttg   1020

tgaagtagga atggcctaca gcatggaaaa ataccgaagg acaggcaaca tggcacgagt   1080

gatggtgcga tacatgaaat atctgcgtca gaagaatatt ccattttaca tctctgtgtt   1140

ggaagaaaat gaagactccc gcagatttgt ggggcagttt ggtttctttg aggcctcctg   1200

tgagtggcac caatggactt gctacccaca gaatctagtt ccattttaga caatgaagct   1260

gcttagtaat ctctgccaag ccatctctta atattaaagc agacaccaca gaatagattt   1320

cttcacttac aaatgcatat tgggcactta taatacagca ggaactcttc tcacctggag   1380

ccttgatgtt aaaagacaca gccatgctct tgaggagctt acaatcctgg ctggaggcag   1440

gggagggtat attctttaaa tatgcttaag tgttataggg aaagacgggg ttaccagtaa   1500

acatgtaact agaaagccag gctcagttct tacctctggg aatcagaact ctttatgcaa   1560

cttggttaat agaatctact atctggaaga taaatgaagg attttaataa aattttcaat   1620

agaataaacc t                                                        1631


<210>  7923
<211>  302
<212>  PRT
<213>  Homo sapiens

<400>  7923

Met Ile Leu Leu Asn Asn Ser His Lys Leu Leu Ala Leu Tyr Lys Ser 
1               5                   10                  15


Leu Ala Arg Ser Ile Pro Glu Ser Leu Lys Val Tyr Gly Ser Val Tyr 
            20                  25                  30


His Ile Asn His Gly Asn Pro Phe Asn Met Glu Val Leu Val Asp Ser 
        35                  40                  45


Trp Pro Glu Tyr Gln Met Val Ile Ile Arg Pro Gln Lys Gln Glu Met 
    50                  55                  60


Thr Asp Asp Met Asp Ser Tyr Thr Asn Val Tyr Arg Met Phe Ser Lys 
65                  70                  75                  80


Glu Pro Gln Lys Ser Glu Glu Val Leu Lys Asn Cys Glu Ile Val Asn 
                85                  90                  95


Trp Lys Gln Arg Leu Gln Ile Gln Gly Leu Gln Glu Ser Leu Gly Glu 
            100                 105                 110


Gly Ile Arg Val Ala Thr Phe Ser Lys Ser Val Lys Val Glu His Ser 
        115                 120                 125


Arg Ala Leu Leu Leu Val Thr Glu Asp Ile Leu Lys Leu Asn Ala Ser 
    130                 135                 140


Ser Lys Ser Lys Leu Gly Ser Trp Ala Glu Thr Gly His Pro Asp Asp 
145                 150                 155                 160


Glu Phe Glu Ser Glu Thr Pro Asn Phe Lys Tyr Ala Gln Leu Asp Val 
                165                 170                 175


Ser Tyr Ser Gly Leu Val Asn Asp Asn Trp Lys Arg Gly Lys Asn Glu 
            180                 185                 190


Arg Ser Leu His Tyr Ile Lys Arg Cys Ile Glu Asp Leu Pro Ala Ala 
        195                 200                 205


Cys Met Leu Gly Pro Glu Gly Val Pro Val Ser Trp Val Thr Met Asp 
    210                 215                 220


Pro Ser Cys Glu Val Gly Met Ala Tyr Ser Met Glu Lys Tyr Arg Arg 
225                 230                 235                 240


Thr Gly Asn Met Ala Arg Val Met Val Arg Tyr Met Lys Tyr Leu Arg 
                245                 250                 255


Gln Lys Asn Ile Pro Phe Tyr Ile Ser Val Leu Glu Glu Asn Glu Asp 
            260                 265                 270


Ser Arg Arg Phe Val Gly Gln Phe Gly Phe Phe Glu Ala Ser Cys Glu 
        275                 280                 285


Trp His Gln Trp Thr Cys Tyr Pro Gln Asn Leu Val Pro Phe 
    290                 295                 300


<210>  7924
<211>  2603
<212>  DNA
<213>  Homo sapiens

<400>  7924
gcatttgtgg cgctaaaaaa agggatgggc gtgggagatt ccaggacttg tgctcgctga     60

agatacaact gttagtccaa gctcctgtat cagcagtgct tgcacctcat aggtgatgat    120

catgaggggg acaaggagcc tctagactta agagacaagt tgccagcatt ctccagatgg    180

agtgtttccc tccgcagcac cccctgctgg tcagtttgac aagcaggtga acagaagttc    240

tcaaatacac aatagtagat tctatcaatc aagtttcata aagagttctg attcccagag    300

atagcagatt ctgtcaacca catttcataa agagttctga ttctaagaga gccatacacc    360

tgaaggaggg atggaaagac taggagagcc tgggatcctc agagatggag atctggatgt    420

gaagagaaag agaaaaacaa aagtcaacag acagtactgt gaccaagtca gtgatggtga    480

gatcagcagc atctctagga cccttctgat tgacatgaag tcaccatcaa gtaggcagaa    540

ctcacagcag gagacctgtc tctgatgctg ctgagccact ttgacaatcg ttatatagaa    600

atctgattgg atgccgtgaa actggacatc agcaaaatgt cagaatggga ctttctagca    660

tttatcctca cacagaaaca tcaatttaaa caactatcta tgcatgaaaa taccttcaga    720

agagctaaga aaaccaggtg aaaggttaca gaaatgttgt gtagcagaga aataagaaaa    780

gattaattga agagcatagg aagaacaatt tttcatttcc tgtgtcaccc ctcccacaac    840

accaggcagc agggcacaga gagaggcaat ctctgtgtcg aagaagaaaa gtgaagtgag    900

cactgaactt tgccttggac tccaacgcag agcctgcttc agtaaaatcc agtaatgggt    960

atgcgactat tgcccgaaac tccaggctag tacctgcaca ctaagccaga ccagatcaca   1020

cagcccaggc tccaggcttg cctggtggac ttggtttctg ggtatatcct catgccaggt   1080

ctaccccagt gccttggatg tcagacagtc tttgggacca ggccagcccc agtgactcca   1140

ggctccagac tgctcccaga acaaggccgg cctcgacaac tccaggtttc aagccagccc   1200

caggaccagg ctagctcctg caactctagt caccatgcca gtgtccatat atccaacccc   1260

taatctggcc cctgtggata caggctcgag gactgcctag cacaaggcta gcccctgtgg   1320

tcgcagactc caagtccacc ctaggttcca gaccggccca gaactagatt ggctcacacc   1380

aatccaggat tcaggcccac cccatttcca ggttggcagc cctagcccta ggccttagtc   1440

aggtatctgg caagcatctg cagacccagg ctccaggcct cccgaggcct aagccagttt   1500

ctgccacccc actctccagg ccagttccta tggtcccatc ctctagcaga cccagggtcc   1560

aggcccatca cagttgactc cagtattggg caggtgccta cagacccagt atctagtact   1620

gcctctgtgg acttaggttc cagtccagtt cctacagccc taggacccaa gccacccttt   1680

gtggccctag tgtccatgcc cacttctgaa tatgttggtt ctaggacaga tctcacacaa   1740

ccagcctcca ggccattcca caattcttgg cccacccctg tggctacaag caccagtcta   1800

gcacctatgg tctcaaactt tagactggcc ccatctcacc acagccctag gccagcatca   1860

gactccaggc tggtttttgt aacccagcat ccaacaaact cagggcccag ctgtgctcta   1920

gcagacccag ggtacaggcc gacttcatta gaccctgttg ctaggctggc catcatggac   1980

aaagtctcta ggaccatctc tgaagactca ggctccaggt ctgcccccgt ctaccaagat   2040

cccaggccca tttctccaga ttccggctcc agtcctgcac cagtaccagg ccagtcccca   2100

tggactcaga tgccaggctt atcccagcag actcagacac tatgctcatt ccaaaatctg   2160

gccagcccct gcagacacag gctcaatgca cgcctcagag ccatgttagc ccctgtggac   2220

ccatgctcag tccagcacct actgttaaca gcctctgtac ctgcccttat agaaattggc   2280

tttacgttca tccccacata cccaatgaaa agatccaccc cagttgatcc aggcttcagg   2340

cccaactcta cagacccagg aaacaggcct accatctgct aacacaggca ccaggccagc   2400

ctgcctgagg actttggcaa caagttcacc tgcagaccac actagacacc ctacaaagag   2460

ttgctggatg actaggaaag ggtttttcca gataaagccg gtatgcaaga actagaataa   2520

gtttcttgtt tttcaaatgt gcagacacta atgcactgcc taaaaatcaa gatcaagaac   2580

aatcagagaa aaatgatacc acc                                           2603


<210>  7925
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  7925

Met Glu Arg Leu Gly Glu Pro Gly Ile Leu Arg Asp Gly Asp Leu Asp 
1               5                   10                  15


Val Lys Arg Lys Arg Lys Thr Lys Val Asn Arg Gln Tyr Cys Asp Gln 
            20                  25                  30


Val Ser Asp Gly Glu Ile Ser Ser Ile Ser Arg Thr Leu Leu Ile Asp 
        35                  40                  45


Met Lys Ser Pro Ser Ser Arg Gln Asn Ser Gln Gln Glu Thr Cys Leu 
    50                  55                  60


<210>  7926
<211>  2099
<212>  DNA
<213>  Homo sapiens

<400>  7926
agtgttggcc aatcccagca gccatacttc aactactcat agactgctga atgttcaaac     60

tgtgttcaaa taagatggtg tcacaagaag gatctgaagt ggagcttcta gtatccccag    120

gagcgcgaag tgaacacgga aggtacctgc aggatccaat tgtgtccatt gatctctcag    180

agtggctgag gataatagag tttcttcttc aaggtctcaa ggtgtatggc tctgtgtatc    240

acatcaatca cgggaacccc ttcaacatgg aggtgctggt ggattcctgg cctgaatatc    300

agatggttat tatccggcct caaaagcagg agatgactga tgacatggat tcatacacaa    360

acgtatatcg tatgttctcc aaagagcctc aaaaatcaga agaagttttg aaaaattgtg    420

agatcgtaaa ctggaaacag agactccaaa tccaaggtct tcaagaaagt ttaggtgagg    480

ggataagagt ggctacattt tcaaagtcag tgaaagtaga gcattcgaga gcactcctct    540

tggttacgga agatattctg aagctcaatg cctccagtaa aagcaagctt ggaagctggg    600

ctgagacagg ccacccagat gatgaatttg aaagtgaaac tcccaacttt aagtatgccc    660

agctggatgt ctcttattct gggctggtaa atgacaactg gaagcgaggg aagaatgaga    720

ggagcctgca ttacatcaag cgctgcatag aagacctgcc agcagcctgt atgctcggcc    780

cagagggagt cccggtctca tgggtaacca tggacccttc ttgtgaagta ggaatggcct    840

acagcatgga aaaataccga aggacaggca acatggcacg agtgatggtg cgatacatga    900

aatatctgcg tcagaagaat attccatttt acatctctgt gttggaagaa aatgaagact    960

cccgcagatt tgtggggcag tttggtttct ttgaggcctc ctgtgagtgg caccaatgga   1020

cttgctaccc acagaatcta gttccatttt agacaatgaa gctgcttagt aatctctgcc   1080

aagccatctc ttaatattaa agcagacacc acagaataga tttcttcact tacaaatgca   1140

tattgggcac ttataataca gcaggaactc ttctcacctg gagccttgat gttaaaagac   1200

acagccatgc tcttgaggag cttacaatcc tggctggagg caggggaggg tatattcttt   1260

aaatatgctt aagtgttata gggaaagacg gggttaccag taaacatgta actagaaagc   1320

caggctcagt tcttacctct gggaatcaga actctttatg caacttggtt aatagaatct   1380

actatctgga agataaatga aggattttaa taaaattttc aatagaataa acctaatctg   1440

tatggatact ttatcaaaaa tgaatgtccc tgctatttct ggatttatga ggcaatggta   1500

cactaaagaa tggaatcagt tcagtgaata gaaaggtatc caaggtgaag cctgagacga   1560

atggctttcc caggctacct tccatcactg ttgtacagaa aagaaatcca gagaatcaaa   1620

tggactggcc ttgggggtct ctgctatgga aatgccattt tttgtgtctc ctttctccta   1680

ctctttctca catcctcttc atgattgaag catggcacaa ggcaaggtgt tgcctgcgag   1740

tctggttgta agttcagcct ttggtgtttg cactactgct atcataaggg gtcagggaca   1800

ttccggggag aagtgaccac taaggtgagg attagagagt gagtagaagt gagccagaca   1860

aaaaaagcag aaaatgcaga tgatggaaag gacatgtgcc atgcactatc ataagaactt   1920

cctaactgaa cactgatact acaattctga atccctgatc ttaaaaaata attatacttc   1980

accaacaaaa cttggcctct tttggttcca ctctgccacc ctgccattgg aacttggatt   2040

actgtgaaca ttgcagctat agcaaaataa aaaataaaaa aaataaataa ttggcattt    2099


<210>  7927
<211>  333
<212>  PRT
<213>  Homo sapiens

<400>  7927

Met Phe Lys Leu Cys Ser Asn Lys Met Val Ser Gln Glu Gly Ser Glu 
1               5                   10                  15


Val Glu Leu Leu Val Ser Pro Gly Ala Arg Ser Glu His Gly Arg Tyr 
            20                  25                  30


Leu Gln Asp Pro Ile Val Ser Ile Asp Leu Ser Glu Trp Leu Arg Ile 
        35                  40                  45


Ile Glu Phe Leu Leu Gln Gly Leu Lys Val Tyr Gly Ser Val Tyr His 
    50                  55                  60


Ile Asn His Gly Asn Pro Phe Asn Met Glu Val Leu Val Asp Ser Trp 
65                  70                  75                  80


Pro Glu Tyr Gln Met Val Ile Ile Arg Pro Gln Lys Gln Glu Met Thr 
                85                  90                  95


Asp Asp Met Asp Ser Tyr Thr Asn Val Tyr Arg Met Phe Ser Lys Glu 
            100                 105                 110


Pro Gln Lys Ser Glu Glu Val Leu Lys Asn Cys Glu Ile Val Asn Trp 
        115                 120                 125


Lys Gln Arg Leu Gln Ile Gln Gly Leu Gln Glu Ser Leu Gly Glu Gly 
    130                 135                 140


Ile Arg Val Ala Thr Phe Ser Lys Ser Val Lys Val Glu His Ser Arg 
145                 150                 155                 160


Ala Leu Leu Leu Val Thr Glu Asp Ile Leu Lys Leu Asn Ala Ser Ser 
                165                 170                 175


Lys Ser Lys Leu Gly Ser Trp Ala Glu Thr Gly His Pro Asp Asp Glu 
            180                 185                 190


Phe Glu Ser Glu Thr Pro Asn Phe Lys Tyr Ala Gln Leu Asp Val Ser 
        195                 200                 205


Tyr Ser Gly Leu Val Asn Asp Asn Trp Lys Arg Gly Lys Asn Glu Arg 
    210                 215                 220


Ser Leu His Tyr Ile Lys Arg Cys Ile Glu Asp Leu Pro Ala Ala Cys 
225                 230                 235                 240


Met Leu Gly Pro Glu Gly Val Pro Val Ser Trp Val Thr Met Asp Pro 
                245                 250                 255


Ser Cys Glu Val Gly Met Ala Tyr Ser Met Glu Lys Tyr Arg Arg Thr 
            260                 265                 270


Gly Asn Met Ala Arg Val Met Val Arg Tyr Met Lys Tyr Leu Arg Gln 
        275                 280                 285


Lys Asn Ile Pro Phe Tyr Ile Ser Val Leu Glu Glu Asn Glu Asp Ser 
    290                 295                 300


Arg Arg Phe Val Gly Gln Phe Gly Phe Phe Glu Ala Ser Cys Glu Trp 
305                 310                 315                 320


His Gln Trp Thr Cys Tyr Pro Gln Asn Leu Val Pro Phe 
                325                 330


<210>  7928
<211>  1400
<212>  DNA
<213>  Homo sapiens

<400>  7928
atcccagcag ccatacttca actactcata gactgctgaa tgttcaaact gtgttcaaat     60

aagatggtgt cacaagaagg atctgaagtg gagcttctag tatccccagg agcgcgaagt    120

gaacacggaa ggtacctgca ggatccaatt gtgtccattg atctctcaga gtggctgagg    180

ataataggtg tatggctctg tgtatcacat caatcacggg aaccccttca acatggaggt    240

gctggtggat tcctggcctg aatatcagat ggttattatc cggcctcaaa agcaggagat    300

gactgatgac atggattcat acacaaacgt atatcgtatg ttctccaaag agcctcaaaa    360

atcagaagaa gttttgaaaa attgtgagat cgtaaactgg aaacagagac tccaaatcca    420

aggtcttcaa gaaagtttag gtgaggggat aagagtggct acattttcaa agtcagtgaa    480

agtagagcat tcgagagcac tcctcttggt tacggaagat attctgaagc tcaatgcctc    540

cagtaaaagc aagcttggaa gctgggctga gacaggccac ccagatgatg aatttgaaag    600

tgaaactccc aactttaagt atgcccagct ggatgtctct tattctgggc tggtaaatga    660

caactggaag cgagggaaga atgagaggag cctgcattac atcaagcgct gcatagaaga    720

cctgccagca gcctgtatgc tcggcccaga gggagtcccg gtctcatggg taaccatgga    780

cccttcttgt gaagtaggaa tggcctacag catggaaaaa taccgaagga caggcaacat    840

ggcacgagtg atggtgcgat acatgaaata tctgcgtcag aagaatattc cattttacat    900

ctctgtgttg gaagaaaatg aagactcccg cagatttgtg gggcagtttg gtttctttga    960

ggcctcctgt gagtggcacc aatggacttg ctacccacag aatctagttc cattttagac   1020

aatgaagctg cttagtaatc tctgccaagc catctcttaa tattaaagca gacaccacag   1080

aatagatttc ttcacttaca aatgcatatt gggcacttat aatacagcag gaactcttct   1140

cacctggagc cttgatgtta aaagacacag ccatgctctt gaggagctta caatcctggc   1200

tggaggcagg ggagggtata ttctttaaat atgcttaagt gttataggga aagacggggt   1260

taccagtaaa catgtaacta gaaagccagg ctcagttctt acctctggga atcagaactc   1320

tttatgcaac ttggttaata gaatctacta tctggaagat aaatgaagga ttttaataaa   1380

attttcaata gaataaacct                                               1400


<210>  7929
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7929

Met Glu Val Leu Val Asp Ser Trp Pro Glu Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Met Phe Ser Lys Glu Pro Gln Lys Ser Glu Glu Val Leu 
        35                  40                  45


Lys Asn Cys Glu Ile Val Asn Trp Lys Gln Arg Leu Gln Ile Gln Gly 
    50                  55                  60


Leu Gln Glu Ser Leu Gly Glu Gly Ile Arg Val Ala Thr Phe Ser Lys 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Leu Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Asn Ala Ser Ser Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Phe Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asp Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Arg Gly Lys Asn Glu Arg Ser Leu His Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Ile Glu Asp Leu Pro Ala Ala Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Val Gly Met Ala Tyr 
            180                 185                 190


Ser Met Glu Lys Tyr Arg Arg Thr Gly Asn Met Ala Arg Val Met Val 
        195                 200                 205


Arg Tyr Met Lys Tyr Leu Arg Gln Lys Asn Ile Pro Phe Tyr Ile Ser 
    210                 215                 220


Val Leu Glu Glu Asn Glu Asp Ser Arg Arg Phe Val Gly Gln Phe Gly 
225                 230                 235                 240


Phe Phe Glu Ala Ser Cys Glu Trp His Gln Trp Thr Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Phe 
            260


<210>  7930
<211>  2065
<212>  DNA
<213>  Homo sapiens

<400>  7930
atcccagcag ccatacttca actactcata gactgctgaa tgttcaaact gtgttcaaat     60

aagatggtgt cacaagaagg atctgaagtg gagcttctag tatccccagg agcgcgaagt    120

gaacacggaa ggtacctgca ggatccaatt gtgtccattg atctctcaga gtggctgagg    180

ataataggtg tatggctctg tgtatcacat caatcacggg aaccccttca acatggaggt    240

gctggtggat tcctggcctg aatatcagat ggttattatc cggcctcaaa agcaggagat    300

gactgatgac atggattcat acacaaacgt atatcgtatg ttctccaaag agcctcaaaa    360

atcagaagaa gttttgaaaa attgtgagat cgtaaactgg aaacagagac tccaaatcca    420

aggtcttcaa gaaagtttag gtgaggggat aagagtggct acattttcaa agtcagtgaa    480

agtagagcat tcgagagcac tcctcttggt tacggaagat attctgaagc tcaatgcctc    540

cagtaaaagc aagcttggaa gctgggctga gacaggccac ccagatgatg aatttgaaag    600

tgaaactccc aactttaagt atgcccagct ggatgtctct tattctgggc tggtaaatga    660

caactggaag cgagggaaga atgagaggag cctgcattac atcaagcgct gcatagaaga    720

cctgccagca gcctgtatgc tcggcccaga gggagtcccg gtctcatggg taaccatgga    780

cccttcttgt gaagtaggaa tggcctacag catggaaaaa taccgaagga caggcaacat    840

ggcacgagtg atggtgcgat acatgaaata tctgcgtcag aagaatattc cattttacat    900

ctctgtgttg gaagaaaatg aagactcccg cagatttgtg gggcagtttg gtttctttga    960

ggcctcctgt gagtggcacc aatggacttg ctacccacag aatctagttc cattttagac   1020

aatgaagctg cttagtaatc tctgccaagc catctcttaa tattaaagca gacaccacag   1080

aatagatttc ttcacttaca aatgcatatt gggcacttat aatacagcag gaactcttct   1140

cacctggagc cttgatgtta aaagacacag ccatgctctt gaggagctta caatcctggc   1200

tggaggcagg ggagggtata ttctttaaat atgcttaagt gttataggga aagacggggt   1260

taccagtaaa catgtaacta gaaagccagg ctcagttctt acctctggga atcagaactc   1320

tttatgcaac ttggttaata gaatctacta tctggaagat aaatgaagga ttttaataaa   1380

attttcaata gaataaacct aatctgtatg gatactttat caaaaatgaa tgtccctgct   1440

atttctggat ttatgaggca atggtacact aaagaatgga atcagttcag tgaatagaaa   1500

ggtatccaag gtgaagcctg agacgaatgg ctttcccagg ctaccttcca tcactgttgt   1560

acagaaaaga aatccagaga atcaaatgga ctggccttgg gggtctctgc tatggaaatg   1620

ccattttttg tgtctccttt ctcctactct ttctcacatc ctcttcatga ttgaagcatg   1680

gcacaaggca aggtgttgcc tgcgagtctg gttgtaagtt cagcctttgg tgtttgcact   1740

actgctatca taaggggtca gggacattcc ggggagaagt gaccactaag gtgaggatta   1800

gagagtgagt agaagtgagc cagacaaaaa aagcagaaaa tgcagatgat ggaaaggaca   1860

tgtgccatgc actatcataa gaacttccta actgaacact gatactacaa ttctgaatcc   1920

ctgatcttaa aaaataatta tacttcacca acaaaacttg gcctcttttg gttccactct   1980

gccaccctgc cattggaact tggattactg tgaacattgc agctatagca aaataaaaaa   2040

taaaaaaaat aaataattgg cattt                                         2065


<210>  7931
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7931

Met Glu Val Leu Val Asp Ser Trp Pro Glu Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Met Phe Ser Lys Glu Pro Gln Lys Ser Glu Glu Val Leu 
        35                  40                  45


Lys Asn Cys Glu Ile Val Asn Trp Lys Gln Arg Leu Gln Ile Gln Gly 
    50                  55                  60


Leu Gln Glu Ser Leu Gly Glu Gly Ile Arg Val Ala Thr Phe Ser Lys 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Leu Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Asn Ala Ser Ser Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Phe Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asp Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Arg Gly Lys Asn Glu Arg Ser Leu His Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Ile Glu Asp Leu Pro Ala Ala Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Val Gly Met Ala Tyr 
            180                 185                 190


Ser Met Glu Lys Tyr Arg Arg Thr Gly Asn Met Ala Arg Val Met Val 
        195                 200                 205


Arg Tyr Met Lys Tyr Leu Arg Gln Lys Asn Ile Pro Phe Tyr Ile Ser 
    210                 215                 220


Val Leu Glu Glu Asn Glu Asp Ser Arg Arg Phe Val Gly Gln Phe Gly 
225                 230                 235                 240


Phe Phe Glu Ala Ser Cys Glu Trp His Gln Trp Thr Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Phe 
            260


<210>  7932
<211>  2360
<212>  DNA
<213>  Homo sapiens

<400>  7932
aaactgtgtt caaataaggc aagcgcccag ttgtaaccaa tctctttgtt tctgtacctg     60

atttctggtt cctgtacatc actttacctt ttttgtctat aaattcattt tgaccacgag    120

gcacccccgg agcctcggtg aatctgctgt gattttgtag gctgccggat tcacaaattg    180

tttgttgctt aatgaaactc ctttaagttt aattcagctg aagtttttct tttatcagat    240

ggtgtcacaa gaaggatctg aagtggagct tctagtatcc ccaggagcgc gaagtgaaca    300

cggaaggtac ctgcaggatc caattgtgtc cattgatctc tcagagtggc tgaggataat    360

agagtttctt cttcaaggtc tcaaggtctg aagcatccca cagaatgatc ctactgaata    420

actcccataa gctgctggcc ctatacaaat ccttggccag gagcatccct gagtccctga    480

aggtgtatgg ctctgtgtat cacatcaatc acgggaaccc cttcaacatg gaggtgctgg    540

tggattcctg gcctgaatat cagatggtta ttatccggcc tcaaaagcag gagatgactg    600

atgacatgga ttcatacaca aacgtatatc gtatgttctc caaagagcct caaaaatcag    660

aagaagtttt gaaaaattgt gagatcgtaa actggaaaca gagactccaa atccaaggtc    720

ttcaagaaag tttaggtgag gggataagag tggctacatt ttcaaagtca gtgaaagtag    780

agcattcgag agcactcctc ttggttacgg aagatattct gaagctcaat gcctccagta    840

aaagcaagct tggaagctgg gctgagacag gccacccaga tgatgaattt gaaagtgaaa    900

ctcccaactt taagtatgcc cagctggatg tctcttattc tgggctggta aatgacaact    960

ggaagcgagg gaagaatgag aggagcctgc attacatcaa gcgctgcata gaagacctgc   1020

cagcagcctg tatgctcggc ccagagggag tcccggtctc atgggtaacc atggaccctt   1080

cttgtgaagt aggaatggcc tacagcatgg aaaaataccg aaggacaggc aacatggcac   1140

gagtgatggt gcgatacatg aaatatctgc gtcagaagaa tattccattt tacatctctg   1200

tgttggaaga aaatgaagac tcccgcagat ttgtggggca gtttggtttc tttgaggcct   1260

cctgtgagtg gcaccaatgg acttgctacc cacagaatct agttccattt tagacaatga   1320

agctgcttag taatctctgc caagccatct cttaatatta aagcagacac cacagaatag   1380

atttcttcac ttacaaatgc atattgggca cttataatac agcaggaact cttctcacct   1440

ggagccttga tgttaaaaga cacagccatg ctcttgagga gcttacaatc ctggctggag   1500

gcaggggagg gtatattctt taaatatgct taagtgttat agggaaagac ggggttacca   1560

gtaaacatgt aactagaaag ccaggctcag ttcttacctc tgggaatcag aactctttat   1620

gcaacttggt taatagaatc tactatctgg aagataaatg aaggatttta ataaaatttt   1680

caatagaata aacctaatct gtatggatac tttatcaaaa atgaatgtcc ctgctatttc   1740

tggatttatg aggcaatggt acactaaaga atggaatcag ttcagtgaat agaaaggtat   1800

ccaaggtgaa gcctgagacg aatggctttc ccaggctacc ttccatcact gttgtacaga   1860

aaagaaatcc agagaatcaa atggactggc cttgggggtc tctgctatgg aaatgccatt   1920

ttttgtgtct cctttctcct actctttctc acatcctctt catgattgaa gcatggcaca   1980

aggcaaggtg ttgcctgcga gtctggttgt aagttcagcc tttggtgttt gcactactgc   2040

tatcataagg ggtcagggac attccgggga gaagtgacca ctaaggtgag gattagagag   2100

tgagtagaag tgagccagac aaaaaaagca gaaaatgcag atgatggaaa ggacatgtgc   2160

catgcactat cataagaact tcctaactga acactgatac tacaattctg aatccctgat   2220

cttaaaaaat aattatactt caccaacaaa acttggcctc ttttggttcc actctgccac   2280

cctgccattg gaacttggat tactgtgaac attgcagcta tagcaaaata aaaaataaaa   2340

aaaataaata attggcattt                                               2360


<210>  7933
<211>  302
<212>  PRT
<213>  Homo sapiens

<400>  7933

Met Ile Leu Leu Asn Asn Ser His Lys Leu Leu Ala Leu Tyr Lys Ser 
1               5                   10                  15


Leu Ala Arg Ser Ile Pro Glu Ser Leu Lys Val Tyr Gly Ser Val Tyr 
            20                  25                  30


His Ile Asn His Gly Asn Pro Phe Asn Met Glu Val Leu Val Asp Ser 
        35                  40                  45


Trp Pro Glu Tyr Gln Met Val Ile Ile Arg Pro Gln Lys Gln Glu Met 
    50                  55                  60


Thr Asp Asp Met Asp Ser Tyr Thr Asn Val Tyr Arg Met Phe Ser Lys 
65                  70                  75                  80


Glu Pro Gln Lys Ser Glu Glu Val Leu Lys Asn Cys Glu Ile Val Asn 
                85                  90                  95


Trp Lys Gln Arg Leu Gln Ile Gln Gly Leu Gln Glu Ser Leu Gly Glu 
            100                 105                 110


Gly Ile Arg Val Ala Thr Phe Ser Lys Ser Val Lys Val Glu His Ser 
        115                 120                 125


Arg Ala Leu Leu Leu Val Thr Glu Asp Ile Leu Lys Leu Asn Ala Ser 
    130                 135                 140


Ser Lys Ser Lys Leu Gly Ser Trp Ala Glu Thr Gly His Pro Asp Asp 
145                 150                 155                 160


Glu Phe Glu Ser Glu Thr Pro Asn Phe Lys Tyr Ala Gln Leu Asp Val 
                165                 170                 175


Ser Tyr Ser Gly Leu Val Asn Asp Asn Trp Lys Arg Gly Lys Asn Glu 
            180                 185                 190


Arg Ser Leu His Tyr Ile Lys Arg Cys Ile Glu Asp Leu Pro Ala Ala 
        195                 200                 205


Cys Met Leu Gly Pro Glu Gly Val Pro Val Ser Trp Val Thr Met Asp 
    210                 215                 220


Pro Ser Cys Glu Val Gly Met Ala Tyr Ser Met Glu Lys Tyr Arg Arg 
225                 230                 235                 240


Thr Gly Asn Met Ala Arg Val Met Val Arg Tyr Met Lys Tyr Leu Arg 
                245                 250                 255


Gln Lys Asn Ile Pro Phe Tyr Ile Ser Val Leu Glu Glu Asn Glu Asp 
            260                 265                 270


Ser Arg Arg Phe Val Gly Gln Phe Gly Phe Phe Glu Ala Ser Cys Glu 
        275                 280                 285


Trp His Gln Trp Thr Cys Tyr Pro Gln Asn Leu Val Pro Phe 
    290                 295                 300


<210>  7934
<211>  781
<212>  DNA
<213>  Homo sapiens

<400>  7934
aaataaggca agcgcccagt tgtaaccaat ctctttgttt ctgtacctga tttctggttc     60

ctgtacatca ctttaccttt tttgtctata aattcatttt gaccacgagg cacccccgga    120

gcctcggtga atctgctgtg attttgtagg ctgccggatt cacaaattgt ttgttgctta    180

atgaaactcc tttaagttta attcagctga agtttttctt ttatcagatg gtgtcacaag    240

aaggatctga agtggagctt ctagtatccc caggagcgcg aagtgaacac ggaaggtacc    300

tgcaggatcc aattgtgtcc attgatctct cagagtggct gaggataata gagtttcttc    360

ttcaaggtct caaggtctga agcatcccac agaatgatcc tactgaataa ctcccataag    420

ctgctggccc tatacaaatc cttggccagg agcatccctg agtccctgaa ggtcagggaa    480

cagtgggagg tcagggtatg ggagtagggg tgttgaggat gagaaaatag caggcttgtg    540

attctagtcc ttcctgactg tttgcagagg gttggagctg ggaaacagga tgggactggg    600

ggcacaggct gcatatcaag agctgctgct tctctttggg aagaggcagc taggtccact    660

ctgcaggttt tgccactcat ttggagaggc agtggagcat ggtggctacg aacatggttt    720

ggagcctgtc tgaatggata tgcattccaa ggctgccatt ttctagtcag atggctttgt    780

g                                                                    781


<210>  7935
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  7935

Met Val Ser Gln Glu Gly Ser Glu Val Glu Leu Leu Val Ser Pro Gly 
1               5                   10                  15


Ala Arg Ser Glu His Gly Arg Tyr Leu Gln Asp Pro Ile Val Ser Ile 
            20                  25                  30


Asp Leu Ser Glu Trp Leu Arg Ile Ile Glu Phe Leu Leu Gln Gly Leu 
        35                  40                  45


Lys Val 
    50


<210>  7936
<211>  2287
<212>  DNA
<213>  Homo sapiens

<400>  7936
aatattcact tttaattctt tccacaaggg aggaagggca tgggttttgg agacagtcat     60

atatggtttc aaaatctgac tctggcattt atctctaaga acttgagaaa tttacttagt    120

ccctctgaga tttggtgtat tcagaatgaa tatgatacta acagtaccta catcacgagt    180

gttacttgaa tggagatgta taaagtgcat tttaaattca tttgtttcct taacattttc    240

ccttcatttc ttatcttttc agagtttctt cttcaaggtc tcaaggtctg aagcatccca    300

cagaatgatc ctactgaata actcccataa gctgctggcc ctatacaaat ccttggccag    360

gagcatccct gagtccctga aggtcaggga acagtgggag gtcagggtat gggagtaggg    420

gtgttgagga tgagaaaata gcaggcttgt gattctagtc cttcctgact gtttgcagag    480

ggttggagct gggaaacagg atgggactgg gggcacaggc tgcatatcaa gagctgctgc    540

ttctctttgg gaagaggcag ctaggtccac tctgcaggtt ttgccactca tttggagagg    600

cagtggagca tggtggctac gaacatggtt tggagcctgt ctgaatggat atgcattcca    660

aggctgccat tttctagtca gatggctttg tggatgtttc tttccctttc tctgacttta    720

cgtttggttt ttccatcaat gagatgggaa taacgttagc acctacctct taaagttgct    780

atggacactg aataaatcta tacaatataa atgctaagag cattgccaag tgcccagcta    840

gtacacagta gctctttggt atcacaagga cagtcctacc tgtgagttct gcctgcttgc    900

tggtaacttc acgtccatca gtatggtcct ctccaggacc atactgctca tctcaccatc    960

actgacttgg tctcagtacc ttctcttaat ctccattttt ctcttcctct tcacaaccag   1020

atcctcatct ctggggatct caacctctcc tggtcccttt catccctcct tcaggtgtat   1080

ggctctgtgt atcacatcaa tcacgggaac cccttcaaca tggaggtgct ggtggattcc   1140

tggcctgaat atcagatggt tattatccgg cctcaaaagc aggagatgac tgatgacatg   1200

gattcataca caaacgtata tcgtatgttc tccaaagagc ctcaaaaatc agaagaagtt   1260

ttgaaaaatt gtgagatcgt aaactggaaa cagagactcc aaatccaagg tcttcaagaa   1320

agtttaggtg aggggataag agtggctaca ttttcaaagt cagtgaaagt agagcattcg   1380

agagcactcc tcttggttac ggaagatatt ctgaagctca atgcctccag taaaagcaag   1440

cttggaagct gggctgagac aggccaccca gatgatgaat ttgaaagtga aactcccaac   1500

tttaagtatg cccagctgga tgtctcttat tctgggctgg taaatgacaa ctggaagcga   1560

gggaagaatg agaggagcct gcattacatc aagcgctgca tagaagacct gccagcagcc   1620

tgtatgctcg gcccagaggg agtcccggtc tcatgggtaa ccatggaccc ttcttgtgaa   1680

gtaggaatgg cctacagcat ggaaaaatac cgaaggacag gcaacatggc acgagtgatg   1740

gtgcgataca tgaaatatct gcgtcagaag aatattccat tttacatctc tgtgttggaa   1800

gaaaatgaag actcccgcag atttgtgggg cagtttggtt tctttgaggc ctcctgtgag   1860

tggcaccaat ggacttgcta cccacagaat ctagttccat tttagacaat gaagctgctt   1920

agtaatctct gccaagccat ctcttaatat taaagcagac accacagaat agatttcttc   1980

acttacaaat gcatattggg cacttataat acagcaggaa ctcttctcac ctggagcctt   2040

gatgttaaaa gacacagcca tgctcttgag gagcttacaa tcctggctgg aggcagggga   2100

gggtatattc tttaaatatg cttaagtgtt atagggaaag acggggttac cagtaaacat   2160

gtaactagaa agccaggctc agttcttacc tctgggaatc agaactcttt atgcaacttg   2220

gttaatagaa tctactatct ggaagataaa tgaaggattt taataaaatt ttcaatagaa   2280

taaacct                                                             2287


<210>  7937
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7937

Met Glu Val Leu Val Asp Ser Trp Pro Glu Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Met Phe Ser Lys Glu Pro Gln Lys Ser Glu Glu Val Leu 
        35                  40                  45


Lys Asn Cys Glu Ile Val Asn Trp Lys Gln Arg Leu Gln Ile Gln Gly 
    50                  55                  60


Leu Gln Glu Ser Leu Gly Glu Gly Ile Arg Val Ala Thr Phe Ser Lys 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Leu Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Asn Ala Ser Ser Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Phe Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asp Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Arg Gly Lys Asn Glu Arg Ser Leu His Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Ile Glu Asp Leu Pro Ala Ala Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Val Gly Met Ala Tyr 
            180                 185                 190


Ser Met Glu Lys Tyr Arg Arg Thr Gly Asn Met Ala Arg Val Met Val 
        195                 200                 205


Arg Tyr Met Lys Tyr Leu Arg Gln Lys Asn Ile Pro Phe Tyr Ile Ser 
    210                 215                 220


Val Leu Glu Glu Asn Glu Asp Ser Arg Arg Phe Val Gly Gln Phe Gly 
225                 230                 235                 240


Phe Phe Glu Ala Ser Cys Glu Trp His Gln Trp Thr Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Phe 
            260


<210>  7938
<211>  2952
<212>  DNA
<213>  Homo sapiens

<400>  7938
aatattcact tttaattctt tccacaaggg aggaagggca tgggttttgg agacagtcat     60

atatggtttc aaaatctgac tctggcattt atctctaaga acttgagaaa tttacttagt    120

ccctctgaga tttggtgtat tcagaatgaa tatgatacta acagtaccta catcacgagt    180

gttacttgaa tggagatgta taaagtgcat tttaaattca tttgtttcct taacattttc    240

ccttcatttc ttatcttttc agagtttctt cttcaaggtc tcaaggtctg aagcatccca    300

cagaatgatc ctactgaata actcccataa gctgctggcc ctatacaaat ccttggccag    360

gagcatccct gagtccctga aggtcaggga acagtgggag gtcagggtat gggagtaggg    420

gtgttgagga tgagaaaata gcaggcttgt gattctagtc cttcctgact gtttgcagag    480

ggttggagct gggaaacagg atgggactgg gggcacaggc tgcatatcaa gagctgctgc    540

ttctctttgg gaagaggcag ctaggtccac tctgcaggtt ttgccactca tttggagagg    600

cagtggagca tggtggctac gaacatggtt tggagcctgt ctgaatggat atgcattcca    660

aggctgccat tttctagtca gatggctttg tggatgtttc tttccctttc tctgacttta    720

cgtttggttt ttccatcaat gagatgggaa taacgttagc acctacctct taaagttgct    780

atggacactg aataaatcta tacaatataa atgctaagag cattgccaag tgcccagcta    840

gtacacagta gctctttggt atcacaagga cagtcctacc tgtgagttct gcctgcttgc    900

tggtaacttc acgtccatca gtatggtcct ctccaggacc atactgctca tctcaccatc    960

actgacttgg tctcagtacc ttctcttaat ctccattttt ctcttcctct tcacaaccag   1020

atcctcatct ctggggatct caacctctcc tggtcccttt catccctcct tcaggtgtat   1080

ggctctgtgt atcacatcaa tcacgggaac cccttcaaca tggaggtgct ggtggattcc   1140

tggcctgaat atcagatggt tattatccgg cctcaaaagc aggagatgac tgatgacatg   1200

gattcataca caaacgtata tcgtatgttc tccaaagagc ctcaaaaatc agaagaagtt   1260

ttgaaaaatt gtgagatcgt aaactggaaa cagagactcc aaatccaagg tcttcaagaa   1320

agtttaggtg aggggataag agtggctaca ttttcaaagt cagtgaaagt agagcattcg   1380

agagcactcc tcttggttac ggaagatatt ctgaagctca atgcctccag taaaagcaag   1440

cttggaagct gggctgagac aggccaccca gatgatgaat ttgaaagtga aactcccaac   1500

tttaagtatg cccagctgga tgtctcttat tctgggctgg taaatgacaa ctggaagcga   1560

gggaagaatg agaggagcct gcattacatc aagcgctgca tagaagacct gccagcagcc   1620

tgtatgctcg gcccagaggg agtcccggtc tcatgggtaa ccatggaccc ttcttgtgaa   1680

gtaggaatgg cctacagcat ggaaaaatac cgaaggacag gcaacatggc acgagtgatg   1740

gtgcgataca tgaaatatct gcgtcagaag aatattccat tttacatctc tgtgttggaa   1800

gaaaatgaag actcccgcag atttgtgggg cagtttggtt tctttgaggc ctcctgtgag   1860

tggcaccaat ggacttgcta cccacagaat ctagttccat tttagacaat gaagctgctt   1920

agtaatctct gccaagccat ctcttaatat taaagcagac accacagaat agatttcttc   1980

acttacaaat gcatattggg cacttataat acagcaggaa ctcttctcac ctggagcctt   2040

gatgttaaaa gacacagcca tgctcttgag gagcttacaa tcctggctgg aggcagggga   2100

gggtatattc tttaaatatg cttaagtgtt atagggaaag acggggttac cagtaaacat   2160

gtaactagaa agccaggctc agttcttacc tctgggaatc agaactcttt atgcaacttg   2220

gttaatagaa tctactatct ggaagataaa tgaaggattt taataaaatt ttcaatagaa   2280

taaacctaat ctgtatggat actttatcaa aaatgaatgt ccctgctatt tctggattta   2340

tgaggcaatg gtacactaaa gaatggaatc agttcagtga atagaaaggt atccaaggtg   2400

aagcctgaga cgaatggctt tcccaggcta ccttccatca ctgttgtaca gaaaagaaat   2460

ccagagaatc aaatggactg gccttggggg tctctgctat ggaaatgcca ttttttgtgt   2520

ctcctttctc ctactctttc tcacatcctc ttcatgattg aagcatggca caaggcaagg   2580

tgttgcctgc gagtctggtt gtaagttcag cctttggtgt ttgcactact gctatcataa   2640

ggggtcaggg acattccggg gagaagtgac cactaaggtg aggattagag agtgagtaga   2700

agtgagccag acaaaaaaag cagaaaatgc agatgatgga aaggacatgt gccatgcact   2760

atcataagaa cttcctaact gaacactgat actacaattc tgaatccctg atcttaaaaa   2820

ataattatac ttcaccaaca aaacttggcc tcttttggtt ccactctgcc accctgccat   2880

tggaacttgg attactgtga acattgcagc tatagcaaaa taaaaaataa aaaaaataaa   2940

taattggcat tt                                                       2952


<210>  7939
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7939

Met Glu Val Leu Val Asp Ser Trp Pro Glu Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Met Phe Ser Lys Glu Pro Gln Lys Ser Glu Glu Val Leu 
        35                  40                  45


Lys Asn Cys Glu Ile Val Asn Trp Lys Gln Arg Leu Gln Ile Gln Gly 
    50                  55                  60


Leu Gln Glu Ser Leu Gly Glu Gly Ile Arg Val Ala Thr Phe Ser Lys 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Leu Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Asn Ala Ser Ser Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Phe Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asp Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Arg Gly Lys Asn Glu Arg Ser Leu His Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Ile Glu Asp Leu Pro Ala Ala Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Val Gly Met Ala Tyr 
            180                 185                 190


Ser Met Glu Lys Tyr Arg Arg Thr Gly Asn Met Ala Arg Val Met Val 
        195                 200                 205


Arg Tyr Met Lys Tyr Leu Arg Gln Lys Asn Ile Pro Phe Tyr Ile Ser 
    210                 215                 220


Val Leu Glu Glu Asn Glu Asp Ser Arg Arg Phe Val Gly Gln Phe Gly 
225                 230                 235                 240


Phe Phe Glu Ala Ser Cys Glu Trp His Gln Trp Thr Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Phe 
            260


<210>  7940
<211>  571
<212>  DNA
<213>  Homo sapiens

<400>  7940
atttgtggcg ctaaaaaaag ggatgggcgt gggagattcc aggacttgtg ctcgctgaag     60

atacaactgt tagtccaagg ggtgaccctg gagatcatta ccaaaattta aaaatttcac    120

cactgggcac acatgttacc cttctcgtga tggcatggca aagcttgatt tgcaagagtt    180

tcttttggat tgtccccaat gattcccttt aaaaatagga gctccttcaa gctcctgtat    240

cagcagtgct tgcacctcat aggtgatgat catgaggggg acaaggagcc tctagactta    300

agagacaagt tgccagcatt ctccagatgg agtgtttccc tccgcagcac cccctgctgg    360

tcagtttgac aagcaggtga acagaagttc tcaaatacac aatagtagat tctatcaatc    420

aagtttcata aagagttctg attcccagag gacttatgga gcaaggatga ctgacacaaa    480

cacaaaaatc attctgcctg ttgaatgaat cataaaatac tgtctttgat ccaggaggct    540

tgtgtcatct gccagcattt atgaaactgt g                                   571


<210>  7941
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  7941

Met Ile Pro Phe Lys Asn Arg Ser Ser Phe Lys Leu Leu Tyr Gln Gln 
1               5                   10                  15


Cys Leu His Leu Ile Gly Asp Asp His Glu Gly Asp Lys Glu Pro Leu 
            20                  25                  30


Asp Leu Arg Asp Lys Leu Pro Ala Phe Ser Arg Trp Ser Val Ser Leu 
        35                  40                  45


Arg Ser Thr Pro Cys Trp Ser Val 
    50                  55


<210>  7942
<211>  1355
<212>  DNA
<213>  Homo sapiens

<400>  7942
attgtgtcag aagcagaatc tgaagtggag cttctagtat ccccaggagc actgagtaaa     60

cacagaaggt acctgcggga tccacttgtg tccactgatc tctcagagca gctgaggatc    120

aaagagtttt ttcttgaagg ccttcaggtg tatggctctc tgtttcacat caatcacggg    180

aaccccttca acatggaggt gttggtggac tcctggcccg ggtatcagat ggttattatc    240

cgacctcaaa aacaggagat gactgatgac atggattcat acactaatgt atatcgtata    300

ttctccaaag accctcaaaa atcacaagaa gttttgaaaa attctgagat cataaactgg    360

aaacagaaac tccaaatcca aggttttcaa gaaagtttag gtgaggggat aaaagcagct    420

gcattttcaa attcagtgaa ggtagagcat tcgagagcac tcctctttgt tacggaagat    480

atcctgaagc tctatgccac caataaaagc aagcttggaa gctgggctga gacaggccac    540

ccagatgacg aattggagag cgagactccc aattttaagt atgcccagct gaatgtgtct    600

tattctgggc tggtaaatga caactggaag ctagggatga ataagaggag cctgcattac    660

atcaagcgct gcctaggagc cctgccagca gtctgtatgc tgggcccaga gggggtcccg    720

gtctcatggg taaccatgga cccttcttgt gaaataggaa tgggctacag tgtggaaaaa    780

taccgaagga gaggcaacgc gacacggatg atggtgcgat acatgaagta tctgtgtcag    840

aagaatattc cattttacgg ctctgtgctg gaagaaaatc aaggcgccat cagaatgaat    900

aaggcactag gtttccttga ggcctcctgt cagtggcacc aatggacctg ctacccacag    960

aatcttgttc cgttgtagac aatgaagctg cttagcaatc ttgggcaagc catctcttaa   1020

tattaaagca gacaccacag aatagctttc ttcacttaca aatgttgatt gggcatttat   1080

gatatggcag gaactccttc tcacatggag acctgatgtt aaaggacaca gccatgctct   1140

tgaggagctt acaatccaag ctggaggcag gggagggtat agtctttaaa tatgcttaag   1200

tgttgtaggg aaggacagag ttaccaataa acatgtaact agaaagccag gctcagttct   1260

tacctctggg aatcagaact ctttatgaaa cttgattgat agaatctact atctggaaga   1320

taattgaaga actttaataa aattgtcaat agaat                              1355


<210>  7943
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7943

Met Glu Val Leu Val Asp Ser Trp Pro Gly Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Ile Phe Ser Lys Asp Pro Gln Lys Ser Gln Glu Val Leu 
        35                  40                  45


Lys Asn Ser Glu Ile Ile Asn Trp Lys Gln Lys Leu Gln Ile Gln Gly 
    50                  55                  60


Phe Gln Glu Ser Leu Gly Glu Gly Ile Lys Ala Ala Ala Phe Ser Asn 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Phe Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Tyr Ala Thr Asn Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Leu Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asn Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Leu Gly Met Asn Lys Arg Ser Leu His Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Leu Gly Ala Leu Pro Ala Val Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Ile Gly Met Gly Tyr 
            180                 185                 190


Ser Val Glu Lys Tyr Arg Arg Arg Gly Asn Ala Thr Arg Met Met Val 
        195                 200                 205


Arg Tyr Met Lys Tyr Leu Cys Gln Lys Asn Ile Pro Phe Tyr Gly Ser 
    210                 215                 220


Val Leu Glu Glu Asn Gln Gly Ala Ile Arg Met Asn Lys Ala Leu Gly 
225                 230                 235                 240


Phe Leu Glu Ala Ser Cys Gln Trp His Gln Trp Thr Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Leu 
            260


<210>  7944
<211>  1351
<212>  DNA
<213>  Homo sapiens

<400>  7944
attgtgtcag aagcagaatc tgaagtggag cttctagtat ccccaggagc actgagtaaa     60

cacagaaggt acctgcagga tccacttgtg tccattgatc tctcagagca gctgaggatc    120

aaagtttttt tcttgaaggg cttgaggagt gtatggctct ctgtttcaca tcaatcacgg    180

gaaccccttc aacatggaag tgttggtgga ctcctggccc gagtatcaga tggttattat    240

ccgacctcaa aaacaggaga tgactgatga catggattca tacactaatg tatatcgtgt    300

attctccaaa gaccctcaaa aatcacaaga agttttgaaa aattctgaga tcataaactg    360

gaaacagaaa ctccaaatcc aaggttttca agaaagttta ggtgagggga taagagcagc    420

tgcattttca aattcagtga aggtagagca ttcgagagca ctcctctttg ttacggaaga    480

tatcctgaag ctctatgcca ccaataaaag caagcttgga agctgggctg agacaggcca    540

cccagatgac gaattggaga gcgagactcc gaactttaag tatgcccagc tgaatgtgtc    600

ttattctggg ctggtaaatg acaactggaa gctagggatg aataagagga gcctgcgtta    660

catcaagcgc tgcctaggag ccctgccagc agcctgtatg ctgggcccag agggggtccc    720

ggtctcatgg gtaaccatgg acccttcttg tgaaatagga atgggctaca gtgtggaaaa    780

ataccgaagg agaggcaatg ggacacggct gatcatgcga tgcatgaagt atctgtgtca    840

gaagaatatt ccattttacg gctctgtgct ggaagaaaat caaggcgtca tcagaaagac    900

tagtgcacta ggtttccttg aggcctcctg tcagtggcac caatggaact gctacccaca    960

gaatcttgtt ccattgtaga caatgaagct gcttagcaat cttgggcaag ccatctctta   1020

atattaaagc agacaccaca gaatagcttt cttcacttac aaatgttgat tgggcatttg   1080

tgatatggca ggaactcttt ctcacatgga gacttgatgt taaaggacac agccatgctc   1140

ttgaggagct tacaatccaa gctggaggca ggggagggta tagtctttaa atatgcttaa   1200

gtgttgtagg gaaggacaga gttaccaata aacatgtaac tagaaagcca ggctcagttc   1260

ttacctctgg gaatcagaac tctttatgaa acttggttga tagaatctac tatctggaag   1320

ataaatgaag aactttaata aaattgtcaa t                                  1351


<210>  7945
<211>  261
<212>  PRT
<213>  Homo sapiens

<400>  7945

Met Glu Val Leu Val Asp Ser Trp Pro Glu Tyr Gln Met Val Ile Ile 
1               5                   10                  15


Arg Pro Gln Lys Gln Glu Met Thr Asp Asp Met Asp Ser Tyr Thr Asn 
            20                  25                  30


Val Tyr Arg Val Phe Ser Lys Asp Pro Gln Lys Ser Gln Glu Val Leu 
        35                  40                  45


Lys Asn Ser Glu Ile Ile Asn Trp Lys Gln Lys Leu Gln Ile Gln Gly 
    50                  55                  60


Phe Gln Glu Ser Leu Gly Glu Gly Ile Arg Ala Ala Ala Phe Ser Asn 
65                  70                  75                  80


Ser Val Lys Val Glu His Ser Arg Ala Leu Leu Phe Val Thr Glu Asp 
                85                  90                  95


Ile Leu Lys Leu Tyr Ala Thr Asn Lys Ser Lys Leu Gly Ser Trp Ala 
            100                 105                 110


Glu Thr Gly His Pro Asp Asp Glu Leu Glu Ser Glu Thr Pro Asn Phe 
        115                 120                 125


Lys Tyr Ala Gln Leu Asn Val Ser Tyr Ser Gly Leu Val Asn Asp Asn 
    130                 135                 140


Trp Lys Leu Gly Met Asn Lys Arg Ser Leu Arg Tyr Ile Lys Arg Cys 
145                 150                 155                 160


Leu Gly Ala Leu Pro Ala Ala Cys Met Leu Gly Pro Glu Gly Val Pro 
                165                 170                 175


Val Ser Trp Val Thr Met Asp Pro Ser Cys Glu Ile Gly Met Gly Tyr 
            180                 185                 190


Ser Val Glu Lys Tyr Arg Arg Arg Gly Asn Gly Thr Arg Leu Ile Met 
        195                 200                 205


Arg Cys Met Lys Tyr Leu Cys Gln Lys Asn Ile Pro Phe Tyr Gly Ser 
    210                 215                 220


Val Leu Glu Glu Asn Gln Gly Val Ile Arg Lys Thr Ser Ala Leu Gly 
225                 230                 235                 240


Phe Leu Glu Ala Ser Cys Gln Trp His Gln Trp Asn Cys Tyr Pro Gln 
                245                 250                 255


Asn Leu Val Pro Leu 
            260


<210>  7946
<211>  883
<212>  DNA
<213>  Homo sapiens

<400>  7946
ggcgggaaaa gttcagctga gagatataaa agagcagtct ttccagcacc tgcaaatcca     60

gagcggcggg cactgacggg cacttgcacc gtgtggacag actctccggt tctggggaaa    120

tccagtccct gttactccat tttggccaga aattcaagga tactgtcatg aagcagacac    180

atgctgacac acctgttgat cattgtctat ctggcataag aaagtgtagc agcaccttta    240

agcttaaaag tgaagtcaac aagcatgaaa cagcccttga aatgcagaat ccaaatttga    300

acaataaaga atgttgtttc acctttacgt tgaatggaaa ctccagaaaa ttagaccgta    360

gtgtgtttac agcatatggt aaacccagcg agagtatcta ctcagccctg agtgctaatg    420

actatttcag tgaaaggata aagaatcagt ttaataagaa cattattgtt tatgaagaaa    480

agacaataga tggacatata aatttaggaa tgcctctcaa gtgcctgcct agtgattctc    540

attttaaaat tacatttggt caaagaaaga gtagcaaaga agatggacac atattacgcc    600

aatgtgaaaa tccaaacatg gaatgcattc tttttcatgt tgttgctata ggaaggacaa    660

gaaagaagat tgttaagatc aacgaacttc atgaaaaagg aagtaaactt tgtatttatg    720

ccttgaaggg tgagactatt gaaggagcct tatgcaagga tggccgtttt cggtctgaca    780

taggtgaatt tgaatggaaa ctaaaggaag gtcataagaa aatttatgga aaacagtcca    840

tggtggatga agtatctgga aaagtcttag aaatggacat ttc                      883


<210>  7947
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  7947

Met Lys Gln Thr His Ala Asp Thr Pro Val Asp His Cys Leu Ser Gly 
1               5                   10                  15


Ile Arg Lys Cys Ser Ser Thr Phe Lys Leu Lys Ser Glu Val Asn Lys 
            20                  25                  30


His Glu Thr Ala Leu Glu Met Gln Asn Pro Asn Leu Asn Asn Lys Glu 
        35                  40                  45


Cys Cys Phe Thr Phe Thr Leu Asn Gly Asn Ser Arg Lys Leu Asp Arg 
    50                  55                  60


Ser Val Phe Thr Ala Tyr Gly Lys Pro Ser Glu Ser Ile Tyr Ser Ala 
65                  70                  75                  80


Leu Ser Ala Asn Asp Tyr Phe Ser Glu Arg Ile Lys Asn Gln Phe Asn 
                85                  90                  95


Lys Asn Ile Ile Val Tyr Glu Glu Lys Thr Ile Asp Gly His Ile Asn 
            100                 105                 110


Leu Gly Met Pro Leu Lys Cys Leu Pro Ser Asp Ser His Phe Lys Ile 
        115                 120                 125


Thr Phe Gly Gln Arg Lys Ser Ser Lys Glu Asp Gly His Ile Leu Arg 
    130                 135                 140


Gln Cys Glu Asn Pro Asn Met Glu Cys Ile Leu Phe His Val Val Ala 
145                 150                 155                 160


Ile Gly Arg Thr Arg Lys Lys Ile Val Lys Ile Asn Glu Leu His Glu 
                165                 170                 175


Lys Gly Ser Lys Leu Cys Ile Tyr Ala Leu Lys Gly Glu Thr Ile Glu 
            180                 185                 190


Gly Ala Leu Cys Lys Asp Gly Arg Phe Arg Ser Asp Ile Gly Glu Phe 
        195                 200                 205


Glu Trp Lys Leu Lys Glu Gly His Lys Lys Ile Tyr Gly Lys Gln Ser 
    210                 215                 220


Met Val Asp Glu Val Ser Gly Lys Val Leu Glu Met Asp 
225                 230                 235


<210>  7948
<211>  982
<212>  DNA
<213>  Homo sapiens

<400>  7948
gcgggaaaag ttcagctgag agatataaaa gagcagtctt tccagcacct gcaaatccag     60

agcggcgggc actgacgggc acttgcaccg tgtggacaga ctctccggtt ctggggaaat    120

ccagtccctg ttactccatt ttggccagaa attcaaggat actgtcatga agcagacaca    180

tgctgacaca cctgttgatc attgtctatc tggcataaga aagtgtagca gcacctttaa    240

gcttaaaagt gaagtcaaca agcatgaaac agcccttgaa atgcagaatc caaatttgaa    300

caataaagaa tgttgtttca cctttacgtt gaatggaaac tccagaaaat tagaccgtag    360

tgtgtttaca gcatatggta aacccagcga gagtatctac tcagccctga gtgctaatga    420

ctatttcagt gaaaggataa agaatcagtt taataagaac attattgttt atgaagaaaa    480

gacaatagat ggacatataa atttaggaat gcctctcaag tgcctgccta gtgattctca    540

ttttaaaatt acatttggtc aaagaaagag tagcaaagaa gatggacaca tattacgcca    600

atgtgaaaat ccaaacatgg aatgcattct ttttcatgtt gttgctatag gaaggacaag    660

aaagaagatt gttaagatca acgaacttca tgaaaaagga agtaaacttt gtatttatgc    720

cttgaagggt gagactattg aaggagcctt atgcaaggat ggccgttttc ggtctgacat    780

aggtgaattt gaatggaaac taaaggaagg tcataagaaa atttatggaa aacagtccat    840

ggtggatgaa gtatctggaa aagtcttaga aatggacatt tcaaaaaaaa aagcattaca    900

acagaaagat atccataaaa aaattaaaca gaatgaaagt gccactgatg aaattaatca    960

ccagagtctg atacagtcta ag                                             982


<210>  7949
<211>  271
<212>  PRT
<213>  Homo sapiens

<400>  7949

Met Lys Gln Thr His Ala Asp Thr Pro Val Asp His Cys Leu Ser Gly 
1               5                   10                  15


Ile Arg Lys Cys Ser Ser Thr Phe Lys Leu Lys Ser Glu Val Asn Lys 
            20                  25                  30


His Glu Thr Ala Leu Glu Met Gln Asn Pro Asn Leu Asn Asn Lys Glu 
        35                  40                  45


Cys Cys Phe Thr Phe Thr Leu Asn Gly Asn Ser Arg Lys Leu Asp Arg 
    50                  55                  60


Ser Val Phe Thr Ala Tyr Gly Lys Pro Ser Glu Ser Ile Tyr Ser Ala 
65                  70                  75                  80


Leu Ser Ala Asn Asp Tyr Phe Ser Glu Arg Ile Lys Asn Gln Phe Asn 
                85                  90                  95


Lys Asn Ile Ile Val Tyr Glu Glu Lys Thr Ile Asp Gly His Ile Asn 
            100                 105                 110


Leu Gly Met Pro Leu Lys Cys Leu Pro Ser Asp Ser His Phe Lys Ile 
        115                 120                 125


Thr Phe Gly Gln Arg Lys Ser Ser Lys Glu Asp Gly His Ile Leu Arg 
    130                 135                 140


Gln Cys Glu Asn Pro Asn Met Glu Cys Ile Leu Phe His Val Val Ala 
145                 150                 155                 160


Ile Gly Arg Thr Arg Lys Lys Ile Val Lys Ile Asn Glu Leu His Glu 
                165                 170                 175


Lys Gly Ser Lys Leu Cys Ile Tyr Ala Leu Lys Gly Glu Thr Ile Glu 
            180                 185                 190


Gly Ala Leu Cys Lys Asp Gly Arg Phe Arg Ser Asp Ile Gly Glu Phe 
        195                 200                 205


Glu Trp Lys Leu Lys Glu Gly His Lys Lys Ile Tyr Gly Lys Gln Ser 
    210                 215                 220


Met Val Asp Glu Val Ser Gly Lys Val Leu Glu Met Asp Ile Ser Lys 
225                 230                 235                 240


Lys Lys Ala Leu Gln Gln Lys Asp Ile His Lys Lys Ile Lys Gln Asn 
                245                 250                 255


Glu Ser Ala Thr Asp Glu Ile Asn His Gln Ser Leu Ile Gln Ser 
            260                 265                 270


<210>  7950
<211>  1040
<212>  DNA
<213>  Homo sapiens

<400>  7950
gttcagctga gagatataaa agagcagtct ttccagcacc tgcaaatcca gagcggcggg     60

cactgacggg cacttgcacc gtgtggacag actctccggt tctggggaaa tccagtccct    120

gttactccat tttggccaga aattcaagac atttcaggtg gcagaataaa ttcaatcctt    180

gtttctccat cttatcgagt agtagaagtt agttacattc tctttgaact catcatgaat    240

tccatgaaga ctgaagaaaa caagtcattt agcgctatgg aagatgacca gaggactaga    300

cctgaagttt caaaggatac tgtcatgaag cagacacatg ctgacacacc tgttgatcat    360

tgtctatctg gcataagaaa gtgtagcagc acctttaagc ttaaaagtga agtcaacaag    420

catgaaacag cccttgaaat gcagaatcca aatttgaaca ataaagaatg ttgtttcacc    480

tttacgttga atggaaactc cagaaaatta gaccgtagtg tgtttacagc atatggtaaa    540

cccagcgaga gtatctactc agccctgagt gctaatgact atttcagtga aaggataaag    600

aatcagttta ataagaacat tattgtttat gaagaaaaga caatagatgg acatataaat    660

ttaggaatgc ctctcaagtg cctgcctagt gattctcatt ttaaaattac atttggtcaa    720

agaaagagta gcaaagaaga tggacacata ttacgccaat gtgaaaatcc aaacatggaa    780

tgcattcttt ttcatgttgt tgctatagga aggacaagaa agaagattgt taagatcaac    840

gaacttcatg aaaaaggaag taaactttgt atttatgcct tgaagggtga gactattgaa    900

ggagccttat gcaaggatgg ccgttttcgg tctgacatag gtgaatttga atggaaacta    960

aaggaaggtc ataagaaaat ttatggaaaa cagtccatgg tggatgaagt atctggaaaa   1020

gtcttagaaa tggacatttc                                               1040


<210>  7951
<211>  267
<212>  PRT
<213>  Homo sapiens

<400>  7951

Met Asn Ser Met Lys Thr Glu Glu Asn Lys Ser Phe Ser Ala Met Glu 
1               5                   10                  15


Asp Asp Gln Arg Thr Arg Pro Glu Val Ser Lys Asp Thr Val Met Lys 
            20                  25                  30


Gln Thr His Ala Asp Thr Pro Val Asp His Cys Leu Ser Gly Ile Arg 
        35                  40                  45


Lys Cys Ser Ser Thr Phe Lys Leu Lys Ser Glu Val Asn Lys His Glu 
    50                  55                  60


Thr Ala Leu Glu Met Gln Asn Pro Asn Leu Asn Asn Lys Glu Cys Cys 
65                  70                  75                  80


Phe Thr Phe Thr Leu Asn Gly Asn Ser Arg Lys Leu Asp Arg Ser Val 
                85                  90                  95


Phe Thr Ala Tyr Gly Lys Pro Ser Glu Ser Ile Tyr Ser Ala Leu Ser 
            100                 105                 110


Ala Asn Asp Tyr Phe Ser Glu Arg Ile Lys Asn Gln Phe Asn Lys Asn 
        115                 120                 125


Ile Ile Val Tyr Glu Glu Lys Thr Ile Asp Gly His Ile Asn Leu Gly 
    130                 135                 140


Met Pro Leu Lys Cys Leu Pro Ser Asp Ser His Phe Lys Ile Thr Phe 
145                 150                 155                 160


Gly Gln Arg Lys Ser Ser Lys Glu Asp Gly His Ile Leu Arg Gln Cys 
                165                 170                 175


Glu Asn Pro Asn Met Glu Cys Ile Leu Phe His Val Val Ala Ile Gly 
            180                 185                 190


Arg Thr Arg Lys Lys Ile Val Lys Ile Asn Glu Leu His Glu Lys Gly 
        195                 200                 205


Ser Lys Leu Cys Ile Tyr Ala Leu Lys Gly Glu Thr Ile Glu Gly Ala 
    210                 215                 220


Leu Cys Lys Asp Gly Arg Phe Arg Ser Asp Ile Gly Glu Phe Glu Trp 
225                 230                 235                 240


Lys Leu Lys Glu Gly His Lys Lys Ile Tyr Gly Lys Gln Ser Met Val 
                245                 250                 255


Asp Glu Val Ser Gly Lys Val Leu Glu Met Asp 
            260                 265


<210>  7952
<211>  3531
<212>  DNA
<213>  Homo sapiens

<400>  7952
gttcagctga gagatataaa agagcagtct ttccagcacc tgcaaatcca gagcggcggg     60

cactgacggg cacttgcacc gtgtggacag actctccggt tctggggaaa tccagtccct    120

gttactccat tttggccaga aattcaagac atttcaggtg gcagaataaa ttcaatcctt    180

gtttctccat cttatcgagt agtagaagtt agttacattc tctttgaact catcatgaat    240

tccatgaaga ctgaagaaaa caagtcattt agcgctatgg aagatgacca gaggactaga    300

cctgaagttt caaaggatac tgtcatgaag cagacacatg ctgacacacc tgttgatcat    360

tgtctatctg gcataagaaa gtgtagcagc acctttaagc ttaaaagtga agtcaacaag    420

catgaaacag cccttgaaat gcagaatcca aatttgaaca ataaagaatg ttgtttcacc    480

tttacgttga atggaaactc cagaaaatta gaccgtagtg tgtttacagc atatggtaaa    540

cccagcgaga gtatctactc agccctgagt gctaatgact atttcagtga aaggataaag    600

aatcagttta ataagaacat tattgtttat gaagaaaaga caatagatgg acatataaat    660

ttaggaatgc ctctcaagtg cctgcctagt gattctcatt ttaaaattac atttggtcaa    720

agaaagagta gcaaagaaga tggacacata ttacgccaat gtgaaaatcc aaacatggaa    780

tgcattcttt ttcatgttgt tgctatagga aggacaagaa agaagattgt taagatcaac    840

gaacttcatg aaaaaggaag taaactttgt atttatgcct tgaagggtga gactattgaa    900

ggagccttat gcaaggatgg ccgttttcgg tctgacatag gtgaatttga atggaaacta    960

aaggaaggtc ataagaaaat ttatggaaaa cagtccatgg tggatgaagt atctggaaaa   1020

gtcttagaaa tggacatttc aaaaaaaaaa gcattacaac agaaagatat ccataaaaaa   1080

attaaacaga atgaaagtgc cactgatgaa attaatcacc agagtctgat acagtctaag   1140

aaaaaagtcc acaaaccaaa gaaagatgga gagaccaaag atgtagaaca cagcagagag   1200

caaattctcc cacctcagga tctaagccat tatattaaag ataaaactcg ccagacaatt   1260

cccaggatta gaaattatta cttttgtagt ttgccccgaa aatataggca aataaactca   1320

caagttagac ggaggccgca tctgggtagg cggtatgcta ttaatctgga tgtccaaaag   1380

gaggcaatta atctcttaaa gaattatcaa acgttgaatg aagccataat gcatcagtat   1440

ccgaatttta aagaggaggc acagtgggta agaaaatatt ttcgggaaga acaaaagaga   1500

atgaatcttt caccagctaa gcaattcaac atatataaaa aggacttcgg aaaaatgact   1560

gcaaattctg tttcagttgc aacctgcgaa cagcttacat attatagcaa gtcagttggg   1620

ttcatgcaat gggacaataa tggaaacaca ggtaatgcta cttgctttgt cttcaatggt   1680

ggttatattt tcacctgtcg acatgttgta catcttatgg tgggtaaaaa cacacatcca   1740

agtttgtggc cagatataat tagcaaatgt gcgaaggtaa ccttcactta tacagagttc   1800

tgccctactc ctgacaattg gttttccatt gagccatggc ttaaagtgtc caatgaaaat   1860

ctagattatg ccattttaaa actaaaagaa aatggaaatg cgtttcctcc aggactatgg   1920

cgacagattt ctcctcaacc atctactggt ttgatttatt taattggtca tcctgaaggc   1980

cagatcaaga aaatagatgg ttgtactgtg attcctctaa acgaacgatt gaaaaaatat   2040

ccaaacgatt gtcaagatgg gttggtagat ctctatgata ccaccagtaa tgtatactgt   2100

atgtttaccc aaagaagttt cctatcagag gtttggaaca cacacacgct tagttatgat   2160

acttgtttct ctgatgggtc ctcaggctcc ccagtgttta atgcatctgg caaattggtt   2220

gctttgcata cctttgggct tttttatcaa cgaggattta atgtgcatgc ccttattgaa   2280

tttggttatt ctatggattc tattctttgt gatattaaaa agacaaatga gagcttgtat   2340

aaatcattaa atgatgagaa acttgagacc tacgatgaag agaaaggtaa acaagagtca   2400

tcacttcaag atcatcagat tgaacccatg gaatgttaga aaagagatgc tgtcttcaag   2460

aaaatatgcc aataattcct ggcaaagatt tcatgacaaa gacacttaaa gcaattgcaa   2520

caaaagtgaa aattggcaaa tgagacctaa ttaaatcttc tgcacagcaa aagaaactat   2580

caacagggta aacacacaac ctacggaatg ggagaaaata tttgcaaact atgcatacag   2640

caaagatcta atattcagaa tccattagga acttaaacag attaacaagc aaaaaaaaca   2700

agcaacccca ttaaaaagtg ggcaaaggac atgaacaaac acttttcaaa agaagatata   2760

cacatggcca acaaggatat gaaaaaatac ctgatatcac taatcattag agaaatgcaa   2820

atcaaaaaaa tgccatcaca ctaatcagaa tggctgttat taaaatgcca aaaaattaca   2880

gatgctggcg aggttgcaga gaaaggggaa tgcttataca ctgctagtgg gaaaataaat   2940

tagttcagcc attgtggaaa gcagttgggt gatttctaaa agaacttaaa acagctacca   3000

ttcaagccag caatctcatg actgggtata tgtccaaagg aatataaatt gttctaccat   3060

aaagacatgc acatatatgt tcactgcagc actattcaca atagcaaaac atgaaatcaa   3120

cctaaatgcc catcaatggt agactggata aagaaaatgt gacacatata caccatagca   3180

tactacacag ccataaaaaa gtacaagatc atgtgctttg cagcaacatg gatggaactg   3240

aaggtcatta tcctaagcga actaatgcag gaacagaaag ccaagtacca catgttctct   3300

cataagtgga agctaaatat tgagtacaca tggacacaaa gaagaaaaca acagatatgg   3360

ggcctacttg agggtggagg gtgggaggag ggtgaagact gaaaaactgc ctatggggta   3420

ctatgcttat tacctgggtg atgaaataat ctgaacacaa aaccctggtg acatgcagtt   3480

tacctatata acaaaactgc acatggactc ttaaacctaa ataaaagttt a            3531


<210>  7953
<211>  734
<212>  PRT
<213>  Homo sapiens

<400>  7953

Met Asn Ser Met Lys Thr Glu Glu Asn Lys Ser Phe Ser Ala Met Glu 
1               5                   10                  15


Asp Asp Gln Arg Thr Arg Pro Glu Val Ser Lys Asp Thr Val Met Lys 
            20                  25                  30


Gln Thr His Ala Asp Thr Pro Val Asp His Cys Leu Ser Gly Ile Arg 
        35                  40                  45


Lys Cys Ser Ser Thr Phe Lys Leu Lys Ser Glu Val Asn Lys His Glu 
    50                  55                  60


Thr Ala Leu Glu Met Gln Asn Pro Asn Leu Asn Asn Lys Glu Cys Cys 
65                  70                  75                  80


Phe Thr Phe Thr Leu Asn Gly Asn Ser Arg Lys Leu Asp Arg Ser Val 
                85                  90                  95


Phe Thr Ala Tyr Gly Lys Pro Ser Glu Ser Ile Tyr Ser Ala Leu Ser 
            100                 105                 110


Ala Asn Asp Tyr Phe Ser Glu Arg Ile Lys Asn Gln Phe Asn Lys Asn 
        115                 120                 125


Ile Ile Val Tyr Glu Glu Lys Thr Ile Asp Gly His Ile Asn Leu Gly 
    130                 135                 140


Met Pro Leu Lys Cys Leu Pro Ser Asp Ser His Phe Lys Ile Thr Phe 
145                 150                 155                 160


Gly Gln Arg Lys Ser Ser Lys Glu Asp Gly His Ile Leu Arg Gln Cys 
                165                 170                 175


Glu Asn Pro Asn Met Glu Cys Ile Leu Phe His Val Val Ala Ile Gly 
            180                 185                 190


Arg Thr Arg Lys Lys Ile Val Lys Ile Asn Glu Leu His Glu Lys Gly 
        195                 200                 205


Ser Lys Leu Cys Ile Tyr Ala Leu Lys Gly Glu Thr Ile Glu Gly Ala 
    210                 215                 220


Leu Cys Lys Asp Gly Arg Phe Arg Ser Asp Ile Gly Glu Phe Glu Trp 
225                 230                 235                 240


Lys Leu Lys Glu Gly His Lys Lys Ile Tyr Gly Lys Gln Ser Met Val 
                245                 250                 255


Asp Glu Val Ser Gly Lys Val Leu Glu Met Asp Ile Ser Lys Lys Lys 
            260                 265                 270


Ala Leu Gln Gln Lys Asp Ile His Lys Lys Ile Lys Gln Asn Glu Ser 
        275                 280                 285


Ala Thr Asp Glu Ile Asn His Gln Ser Leu Ile Gln Ser Lys Lys Lys 
    290                 295                 300


Val His Lys Pro Lys Lys Asp Gly Glu Thr Lys Asp Val Glu His Ser 
305                 310                 315                 320


Arg Glu Gln Ile Leu Pro Pro Gln Asp Leu Ser His Tyr Ile Lys Asp 
                325                 330                 335


Lys Thr Arg Gln Thr Ile Pro Arg Ile Arg Asn Tyr Tyr Phe Cys Ser 
            340                 345                 350


Leu Pro Arg Lys Tyr Arg Gln Ile Asn Ser Gln Val Arg Arg Arg Pro 
        355                 360                 365


His Leu Gly Arg Arg Tyr Ala Ile Asn Leu Asp Val Gln Lys Glu Ala 
    370                 375                 380


Ile Asn Leu Leu Lys Asn Tyr Gln Thr Leu Asn Glu Ala Ile Met His 
385                 390                 395                 400


Gln Tyr Pro Asn Phe Lys Glu Glu Ala Gln Trp Val Arg Lys Tyr Phe 
                405                 410                 415


Arg Glu Glu Gln Lys Arg Met Asn Leu Ser Pro Ala Lys Gln Phe Asn 
            420                 425                 430


Ile Tyr Lys Lys Asp Phe Gly Lys Met Thr Ala Asn Ser Val Ser Val 
        435                 440                 445


Ala Thr Cys Glu Gln Leu Thr Tyr Tyr Ser Lys Ser Val Gly Phe Met 
    450                 455                 460


Gln Trp Asp Asn Asn Gly Asn Thr Gly Asn Ala Thr Cys Phe Val Phe 
465                 470                 475                 480


Asn Gly Gly Tyr Ile Phe Thr Cys Arg His Val Val His Leu Met Val 
                485                 490                 495


Gly Lys Asn Thr His Pro Ser Leu Trp Pro Asp Ile Ile Ser Lys Cys 
            500                 505                 510


Ala Lys Val Thr Phe Thr Tyr Thr Glu Phe Cys Pro Thr Pro Asp Asn 
        515                 520                 525


Trp Phe Ser Ile Glu Pro Trp Leu Lys Val Ser Asn Glu Asn Leu Asp 
    530                 535                 540


Tyr Ala Ile Leu Lys Leu Lys Glu Asn Gly Asn Ala Phe Pro Pro Gly 
545                 550                 555                 560


Leu Trp Arg Gln Ile Ser Pro Gln Pro Ser Thr Gly Leu Ile Tyr Leu 
                565                 570                 575


Ile Gly His Pro Glu Gly Gln Ile Lys Lys Ile Asp Gly Cys Thr Val 
            580                 585                 590


Ile Pro Leu Asn Glu Arg Leu Lys Lys Tyr Pro Asn Asp Cys Gln Asp 
        595                 600                 605


Gly Leu Val Asp Leu Tyr Asp Thr Thr Ser Asn Val Tyr Cys Met Phe 
    610                 615                 620


Thr Gln Arg Ser Phe Leu Ser Glu Val Trp Asn Thr His Thr Leu Ser 
625                 630                 635                 640


Tyr Asp Thr Cys Phe Ser Asp Gly Ser Ser Gly Ser Pro Val Phe Asn 
                645                 650                 655


Ala Ser Gly Lys Leu Val Ala Leu His Thr Phe Gly Leu Phe Tyr Gln 
            660                 665                 670


Arg Gly Phe Asn Val His Ala Leu Ile Glu Phe Gly Tyr Ser Met Asp 
        675                 680                 685


Ser Ile Leu Cys Asp Ile Lys Lys Thr Asn Glu Ser Leu Tyr Lys Ser 
    690                 695                 700


Leu Asn Asp Glu Lys Leu Glu Thr Tyr Asp Glu Glu Lys Gly Lys Gln 
705                 710                 715                 720


Glu Ser Ser Leu Gln Asp His Gln Ile Glu Pro Met Glu Cys 
                725                 730


<210>  7954
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  7954
aaatccagag cggcgggcac tgacgggcac ttgcaccgtg tggacagact ctccggttct     60

ggggaaatcc agtccctgtt actccatttt ggccagaaat tcaagacatt tcaggtggca    120

gaataaattc aatccttgtt tctccatctt atcgagtagt agaagttagt tacattctct    180

ttgaactcat catgaattcc atgaagactg aagaaaacaa gtcatttagc gctatggaag    240

atgaccagag gactagacct gaagtttcaa aggtatatct acttttttac aactcctcag    300

aggagtgata gtctaactat agtgccatat gaggatcttg gagataagtt cttaaacaat    360

ggtcgttata agcccttctc ttaggtagtt taaaatatat ttggggagct catacacata    420

agtgcttgtg gaaagcaaaa tgatagagtt aacaatgcta aacgtatgtt aagacaacaa    480

gatgactaac aaacaatata gacacttaaa gtcttggaaa gtgtagacag gcaaaaataa    540

ttagctaatg ttttctgagg aaacactgtg tgc                                 573


<210>  7955
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  7955

Met Thr Arg Gly Leu Asp Leu Lys Phe Gln Arg Tyr Ile Tyr Phe Phe 
1               5                   10                  15


Thr Thr Pro Gln Arg Ser Asp Ser Leu Thr Ile Val Pro Tyr Glu Asp 
            20                  25                  30


Leu Gly Asp Lys Phe Leu Asn Asn Gly Arg Tyr Lys Pro Phe Ser 
        35                  40                  45


<210>  7956
<211>  579
<212>  DNA
<213>  Homo sapiens

<400>  7956
aaatccagag cggcgggcac tgacgggcac ttgcaccgtg tggacagact ctccggttct     60

ggggaaatcc agtccctgtt actccatttt ggccagaaat tcaaggtgtc cccagcgcag    120

ccaatcggct tccgaagtag gtgagttgct gcctgaagag aaaagacaaa ctccagtatc    180

tttcattcca ttggccagac gcgccattcc ccaagtgagt tctgttctcc aaccaaagtg    240

ctggattcca agggactgga agggaaagtc cctaaaaatc acgagttcag gcgtctgaga    300

cttggtggga acggaccttc ctcttagtgc ccaagcctgt tctaattttt aaaaactgat    360

gtctattaag acccaatgtt aactttatga aaatggttcc taaggagatt cacatctctg    420

tgtccgaatt ctgtgtgcag caaacatcat ctcaagtgcg ttttcccaac tacgcttctt    480

tccaggataa aatactctaa gtgacaaatg ttgagtacat tatcaggttc tctgctgttt    540

aaaaagtatc cctgtgcttt gaagatactg ctataattt                           579


<210>  7957
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  7957

Met Lys Met Val Pro Lys Glu Ile His Ile Ser Val Ser Glu Phe Cys 
1               5                   10                  15


Val Gln Gln Thr Ser Ser Gln Val Arg Phe Pro Asn Tyr Ala Ser Phe 
            20                  25                  30


Gln Asp Lys Ile Leu 
        35


<210>  7958
<211>  434
<212>  DNA
<213>  Homo sapiens

<400>  7958
gttctccatg agggctccac ccctgcagca aacttctgcc tggatatcca ggcgtttcca     60

tacatcctgt gaaatctagg tggaggttcc caaacctcaa ttctttactt ctgttcacct    120

gcaggcccaa caccatgtgt aaggcaccaa ggcttggggc ttgcaccctc tgagtcaatg    180

gcctgagcta tatcttggcc ccttttagcc acagctggga cacagggcac caagttctaa    240

gactgcacaa agcagcaaga cctggggttt agcccatgaa accacttttt ctcctcccat    300

cacaagcctg gttacacggt taggtggaaa agacaagttg tatgtagaga tcattatcag    360

aaattgctaa actctgtcat caaaaactct gttggaatgg attttaaaat ttcttaataa    420

aagatgaaac atga                                                      434


<210>  7959
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  7959

Pro Gln Leu Gly His Arg Ala Pro Ser Ser Lys Thr Ala Gln Ser Ser 
1               5                   10                  15


Lys Thr Trp Gly Leu Ala His Glu Thr Thr Phe Ser Pro Pro Ile Thr 
            20                  25                  30


Ser Leu Val Thr Arg Leu Gly Gly Lys Asp Lys Leu Tyr Val Glu Ile 
        35                  40                  45


Ile Ile Arg Asn Cys 
    50


<210>  7960
<211>  2158
<212>  DNA
<213>  Homo sapiens

<400>  7960
ctgggacgct ggcggcagag ccactgtggc agcttgagtc tcgcgcgcgc aggaagcgga     60

ggtggaagtt ggggcgcagg aatgtggctg tccccgcctg taaatcatgg ttggggagga    120

gtcgcggagg caccaggctg gggtctgcag cgcgccatct gctgcagcac acaggaggcg    180

ctgaggctag ttggagacag agtctcactg tgtcacccag gctggagtga agtggcatga    240

tcttggctta ctgaaacctc catctcccag gttcaagcga ttctcatgcc tcagccactt    300

gagtagctgg gactacagga tttcgccatg ttccccaggc tggtctcaaa ctcctgaact    360

caggcagccc gcctaccttg gcctcccaaa gtgctaggat tacagcccaa atgaccctcc    420

aagaccctct ggaggcaccc gcagtgctcc ttaatttgca gctctacaga atgagaccag    480

cgtggcagcc ccctttcagg acagctcccg agacgagacg cgagagcagc ccctaaatct    540

cacccagcaa agccgtttct tcctaaccgg gctggggagt gccgcgcgct gccagcagat    600

ggcgacagag gattagcctg cggaaaccgg cctttttata gccaacaaga gcaaaagcac    660

actgcaatgt ccaaacgaat tgcaggcgtt ttctgctccc tgaagcctgg gaattaattt    720

atatactcag tcccttttcc cttggctggc cattgaagta gttgaaccac aggattggac    780

tgtccagaat cattagccag agttcactgt gagtggacgt cttttagttc tgcttcaacg    840

ctataaccaa cctttaccaa aagcaacaac aaaacaaaaa actgcagaaa ccaatgagtt    900

ctgttcacaa aggatggctc ctcatgtcat cacaccggca aggaatggac gagcctctga    960

tttttctctt cttggctgac tttacaaggt tggatgcagt ccatgaggat catgcagcaa   1020

agacagaaag tgctggagaa gcccaacctg cagggcctca cctttagctg gtttgtgtgg   1080

ttccacttca tgtagctgtt ggaacaccag tctctctaat gtgctctatg ggatagctgt   1140

taccttccac taatttatgt ctaataccta taaacctaaa gtatcttttt aaaaatttta   1200

ttccgtcttt ttggaggaaa tttttgtgca tgccagatat agtgtcaagc attgggattg   1260

ctaagatgaa cgtaacattg tcctcaccac ccattaagtc acaatctagt agatgagtaa   1320

aagtaaaaaa aaaaattaaa aaaagagtta taaccataat acagaagtga acaggttgca   1380

gtggtagcac agagagggct tcagggatgc tgtcacagag gtggtaacat ttgagatata   1440

gattccaaat tcagatgtgt ttgctgttgc aaaattccag ggtctatgtg cccagttcct   1500

gaacattcca gtgataattt ttacctaaaa tttaggtggc aaatgaatct tactataacc   1560

acttggaacc actgtgtttc tggtccatct tgtgaggccc atctttggtt cagagggatg   1620

gaggcagaag tcatacggca ggtaagctca agcagtgata catgacaggg ctttcagaac   1680

tggggccatg aagagcaggc tttatttgca tgctgtttaa aaacaagatt ttacaactga   1740

tttaccctat taaacacttc catgaataac tcagtggaga tttatttgca atagtaggat   1800

caggtgattt gaaatcttta gtgtgtgtgg ttgtagcagg aggagtactg ggttccagca   1860

tttaataaga ggacccatgg ttttatgaaa atgtccagag atataatttt ggttaaggtt   1920

atacctcatc tttggttgta cagttgtttc ttttagtttc agtacaatct aaaacaggaa   1980

atgtctccag ggcatgtcag agaacttagt ggcagctcct cccatcacaa gcctggttac   2040

acggttaggt ggaaaagaca agttgtatgt agagatcatt atcagaaatt gctaaactct   2100

gtcatcaaaa actctgttgg aatggatttt aaaatttctt aataaaagat gaaacatg     2158


<210>  7961
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  7961

Met Ser Pro Gly His Val Arg Glu Leu Ser Gly Ser Ser Ser His His 
1               5                   10                  15


Lys Pro Gly Tyr Thr Val Arg Trp Lys Arg Gln Val Val Cys Arg Asp 
            20                  25                  30


His Tyr Gln Lys Leu Leu Asn Ser Val Ile Lys Asn Ser Val Gly Met 
        35                  40                  45


Asp Phe Lys Ile Ser 
    50


<210>  7962
<211>  1346
<212>  DNA
<213>  Homo sapiens

<400>  7962
ggagctggga cgctggcggc agagccactg tggcagcttg agtctcgcgc gcgcaggaag     60

cggaggtgga agttggggcg caggaatgtg gctgtccccg cctgtaaatc atggttgggg    120

aggagtcgcg gaggcaccag gctggggtct gcagcgcgcc atctgctgca gcacacagga    180

ggcgctgagg ctagttggag acagagtctc actgtgtcac ccaggctgga gtgaagtggc    240

atgatcttgg cttactgaaa cctccatctc ccaggttcaa gcgattctca tgcctcagcc    300

acttgagtag ctgggactac aggatttcgc catgttcccc aggctggtct caaactcctg    360

aactcaggca gcccgcctac cttggcctcc caaagtgcta ggattacagc ccaaatgacc    420

ctccaagacc ctctggaggc acccgcagtg ctccttaatt tgcagctcta cagaatgaga    480

ccagcgtggc agcccccttt caggacagct cccgagacga gacgcgagag cagcccctaa    540

atctcaccca gcaaagccgt ttcttcctaa ccgggctggg gagtgccgcg cgctgccagc    600

agatggcgac agaggattag cctgcggaaa ccgggtggca aatgaatctt actataacca    660

cttggaacca ctgtgtttct ggtccatctt gtgaggccca tctttggttc agagggatgg    720

aggcagaagt catacggcag gtaagctcaa gcagtgatac atgacagggc tttcagaact    780

ggggccatga agagcaggct ttatttgcat gctgtttaaa aacaagattt tacaactgat    840

ttaccctatt aaacacttcc atgaataact cagtggagat ttatttgcaa tagtaggatc    900

aggtgatttg aaatctttag tgtgtgtggt tgtagcagga ggagtactgg gttccagcat    960

ttaataagag gacccatggt tttatgaaaa tgtccagaga tataattttg gttaaggtta   1020

tacctcatct ttggttgtac agttgtttct tttagtttca gtacaatcta aaacaggaaa   1080

tgtcaattca catggtctgg tagagaaaga atgactctaa tgctctacta ttcaggtaga   1140

aatgaagaaa gaagggtgat cacttccatg agcactgtaa gcccttgaat gggcttatag   1200

gcaaatactt atagttaaaa tatgtaactc ccattttagt attggataga atactgtcac   1260

attttttctt attaaatcta catttttacc atctttcttg attgattttg ccaataaaag   1320

ttccttacct ttttataaaa gtcaaa                                        1346


<210>  7963
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  7963

Met Trp Leu Ser Pro Pro Val Asn His Gly Trp Gly Gly Val Ala Glu 
1               5                   10                  15


Ala Pro Gly Trp Gly Leu Gln Arg Ala Ile Cys Cys Ser Thr Gln Glu 
            20                  25                  30


Ala Leu Arg Leu Val Gly Asp Arg Val Ser Leu Cys His Pro Gly Trp 
        35                  40                  45


Ser Glu Val Ala 
    50


<210>  7964
<211>  1324
<212>  DNA
<213>  Homo sapiens

<400>  7964
ctgggacgct ggcggcagag ccactgtggc agcttgagtc tcgcgcgcgc aggaagcgga     60

ggtggaagtt ggggcgcagg aatgtggctg tccccgcctg taaatcatgg ttggggagga    120

gtcgcggagg caccaggctg gggtctgcag cgcgccatct gctgcagcac acaggaggcg    180

ctgaggctag ttggagacag agtctcactg tgtcacccag gctggagtga agtggcatga    240

tcttggctta ctgaaacctc catctcccag gttcaagcga ttctcatgcc tcagccactt    300

gagtagctgg gactacagga tttcgccatg ttccccaggc tggtctcaaa ctcctgaact    360

caggcagccc gcctaccttg gcctcccaaa gtgctaggat tacagcccaa atgaccctcc    420

aagaccctct ggaggcaccc gcagtgctcc ttaatttgca gctctacaga atgagaccag    480

cgtggcagcc ccctttcagg acagctcccg agacgagacg cgagagcagc ccctaaatct    540

cacccagcaa agccgtttct tcctaaccgg gctggggagt gccgcgcgct gccagcagat    600

ggcgacagag gattagcctg cggaaaccgg cctttttata gccaacaaga gcaaaagcac    660

actgcaatgt ccaaacgaat tgcaggcgtt ttctgctccc tgaagcctgg gaattaattt    720

atatactcag tcccttttcc cttggctggc cattgaagta gttgaaccac aggattggac    780

tgtccagaat cattagccag agttcactgt gagtggacgt cttttagttc tgcttcaacg    840

ctataaccaa cctttaccaa aagcaacaac aaaacaaaaa actgcagaaa ccaatgagtt    900

ctgttcacaa aggatggctc ctcatgtcat cacaccggca aggaatggac gagcctctga    960

tttttctctt cttggctgac tttacaaggt tggatgcagt ccatgaggat catgcagcaa   1020

agacagaaag tgctggagaa gcccaacctg cagggcctca cctttagctg gtttgtgtgg   1080

ttccacttca tgtagctgtt ggaacaccag tctctctaat gtgctctatg ggatagctgt   1140

taccttccac taatttatgt ctaataccta taaacctaaa gtatcttttt aaaaatttta   1200

ttccgtcttt ttggaggaaa tttttgtgca tgccagatat agtgtcaagc attgggattg   1260

ctaagatgaa cgtaacattg tcctcaccac ccattaagtc acaatctagt agatgagtaa   1320

aagt                                                                1324


<210>  7965
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  7965

Met Trp Leu Ser Pro Pro Val Asn His Gly Trp Gly Gly Val Ala Glu 
1               5                   10                  15


Ala Pro Gly Trp Gly Leu Gln Arg Ala Ile Cys Cys Ser Thr Gln Glu 
            20                  25                  30


Ala Leu Arg Leu Val Gly Asp Arg Val Ser Leu Cys His Pro Gly Trp 
        35                  40                  45


Ser Glu Val Ala 
    50


<210>  7966
<211>  949
<212>  DNA
<213>  Homo sapiens

<400>  7966
tccttgacgc cgcgagcagg accctgtctc actgaccccg tgcccacggc ggtccttgcc     60

tgcttctatt ctcccggttt ccccagtccc gagtattgga aagcgagagc gaaagcgaaa    120

gcatcctagt cgccgagaca gagtctcact gtgtcaccca ggctggagtg aagtggcatg    180

atcttggctt actgaaacct ccatctccca ggttcaagcg attctcatgc ctcagccact    240

tgagtagctg ggactacagg atttcgccat gttccccagg ctggtctcaa actcctgaac    300

tcaggcagcc cgcctacctt ggcctcccaa agtgctagga ttacagccca aatgaccctc    360

caagaccctc tggaggcacc cgcagtgctc cttaatttgc agctctacag aatgagacca    420

gcgtggcagc cccctttcag gacagctccc gagacgagac gcgagagcag cccctaaatc    480

tcacccagca aagccgtttc ttcctaaccg ggctggggag tgccgcgcgc tgccagcaga    540

tggcgacaga ggattagcct gcggaaaccg ggtaagggga gggcggagct gaggtgagaa    600

cccacatccc tcatgcccag tggcagcagg acgtggaaat ggtttgccca gccctcactt    660

ctcttggaca gagcttgagc cttctgggaa actgcttttc cctggctgag tgattagcgg    720

gggtgttaag ttgggaagct ggacgttcac ttccatgtgc tcctctgaga accatctgtt    780

ggtctgatgg tgctagatct gaagctggtg agcctcttgg ggcggcctca agggctaaca    840

agatctcaaa tgcccttctc tccatcattt gtggtatcct ggattattgt gaaaatgtat    900

agggattcct ggggaagagt taaggattaa aatataaagg tttaaatat                949


<210>  7967
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  7967

Met Val Leu Asp Leu Lys Leu Val Ser Leu Leu Gly Arg Pro Gln Gly 
1               5                   10                  15


Leu Thr Arg Ser Gln Met Pro Phe Ser Pro Ser Phe Val Val Ser Trp 
            20                  25                  30


Ile Ile Val Lys Met Tyr Arg Asp Ser Trp Gly Arg Val Lys Asp 
        35                  40                  45


<210>  7968
<211>  2569
<212>  DNA
<213>  Homo sapiens

<400>  7968
tcttccaggg cgggcggtgt ggtgcacgca ttgctgtgct ccaactccct cagggcctgt     60

gttgccgcac tctgctgcta tgagcttcct caaaagtttc ccgccgcctg ggccagcgga    120

ggggctcctg cggcagcagc cagacactga ggctgtgctg aacgggaagg gcctcggcac    180

tggtaccctt tacatcgctg agagccgcct gtcttggtta gatggctctg gattaggatt    240

ctcactggaa taccccacca ttagtttaca tgcattatcc agggaccgaa gtgactgtct    300

aggagagcat ttgtatgtta tggtgaatgc caaatttgaa gtggaggcaa tgttcactgc    360

aatgtgcgaa tgccaggcct tgcatccaga tcctgaggat gaggattcag atgactacga    420

tggagaagaa tatgatgtgg aagcacatga acaaggacag ggggacatcc ctacatttta    480

cacctatgaa gaaggattat cccatctaac agcagaaggc caagccacac tggagagatt    540

agaaggaatg ctttctcagt ctgtgagcag ccagtataat atggctgggg tcaggacaga    600

agattcaata agagattatg aagatgggat ggaggtggat accacaccaa cagttgctgg    660

acagtttgag gatgcagatg ttgatcactg aaaatgattt atgcaagttt aagattctgc    720

tcctaagtgt aggagagaac ttggtgcctc ttccactctg gagtgaagtt aatgaaagtc    780

tttttccttt tccaaaaccc aacctgaacc agttctttct tgagacagac tatactgaga    840

caacaagttg tcaccagcag aagatagata atatgacctt tattaacttg atgaattaac    900

ttaaccaaga gggtatttgt agtttactat ttaccctaaa actttctgtg tctgggtacc    960

ctctgagtag gcctataatt cctaccttga ctgtgtgcat catttgtaag ctagcagatc   1020

tatgtggtga aaatgcacag gagcttggta gactgcgggg gaaagagaga gctcctttcg   1080

ccatgtttta ccagtctgct gttataacct cttaggttgt atcctttaat ttccagcctt   1140

ttaggttagt ttctgtaaca gaacaagtga gtctgggatg aagtcctcaa agtacttcaa   1200

atggtaattg ttttgttttt gtaatagctt aacaaataaa cctaggtttt ctatattact   1260

ttgctctcat tcttgactaa aaccattaat gagaaatgtt ttttaaaaaa taatgctggc   1320

aaatatgaga attttgttgg ctttattttt gtttacttgt tgagaagatg aacatgaaat   1380

taataagaaa atatagttat agcttctggc aagtatttag taaggcaaag atttaacaca   1440

tttcagggga tttctgccac ttccttttag atcagcagta atttcttata tttatcaact   1500

ctcaattttt agttttcata gatacctggg tattataagg ctgatttgta attactgatt   1560

tatacttgga cttttgaaat cattatgtgt ccttaaaaat aaggttatac aagctaacct   1620

tcttaacagg atcacatggc taattagtga ctaaactgat gtttggtacc actcagccca   1680

gtgttcattt cagcactgtc acttggtttc ccttatcttg caaggtagac tgaaaaaaaa   1740

cgaattttcc tttttctaac cagactctca gaatttctga gtctgttaac aataggcaag   1800

taaaacagcc acttgaaatg gaaactaaaa tttactgaga cctctgtact agccactgtc   1860

ctgagttctt tattatgtat tataatattc ttaattatct tatgagatac gcttttatcc   1920

cactttatag ttgaggaaac tgagttatag agagaggtaa aataacttgc ttaaggtcat   1980

gtagatagtg aattgtgatt tttgagcctg tgctttaaaa catcatacag ccttaccacc   2040

taccagcagc agaaagcatg cacactctcc ccactgctgc agggtttcag tgttaacatt   2100

tcaatggcca gtacaagagc ttccccagtt tctctgctac ccatctgagc aacacccata   2160

attctatcct agaagtttgt ccattcttca gtaatcagtc aggacattct cacaggctaa   2220

tattagaaat tccatttgag ttccttttaa aaggaacaaa tttataattg tgactttcca   2280

tgaacataaa ttgctctgat agcaaaatgt cgagaagatt cagagtgtac ttggtttctt   2340

gttggtgttg ctgtggtcaa tgcaatatgc aaaaaggcag gagaccaaag catgtgggca   2400

cctctctggg cttatttcct cattagacta agtgactttc aaagattgag ctgtaacatt   2460

cactagatag ttagaaccgt agcattgaga aaatagaagc tgagaaaaaa gagcaggtca   2520

ggcttttaaa agataaaatt tataatgatc agccagacaa tatttattg               2569


<210>  7969
<211>  203
<212>  PRT
<213>  Homo sapiens

<400>  7969

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Val Glu Ala Met Phe Thr Ala Met Cys 
                85                  90                  95


Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser Asp Asp 
            100                 105                 110


Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Glu Gln Gly Gln Gly 
        115                 120                 125


Asp Ile Pro Thr Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His Leu Thr 
    130                 135                 140


Ala Glu Gly Gln Ala Thr Leu Glu Arg Leu Glu Gly Met Leu Ser Gln 
145                 150                 155                 160


Ser Val Ser Ser Gln Tyr Asn Met Ala Gly Val Arg Thr Glu Asp Ser 
                165                 170                 175


Ile Arg Asp Tyr Glu Asp Gly Met Glu Val Asp Thr Thr Pro Thr Val 
            180                 185                 190


Ala Gly Gln Phe Glu Asp Ala Asp Val Asp His 
        195                 200


<210>  7970
<211>  2462
<212>  DNA
<213>  Homo sapiens

<400>  7970
ctcttccagg gcgggcggtg tggtgcacgc attgctgtgc tccaactccc tcagggcctg     60

tgttgccgca ctctgctgct atgagcttcc tcaaaagttt cccgccgcct gggccagcgg    120

aggggctcct gcggcagcag ccagacactg aggctgtgct gaacgggaag ggcctcggca    180

ctggtaccct ttacatcgct gagagccgcc tgtcttggtt agatggctct ggattaggat    240

tctcactgga ataccccacc attagtttac atgcattatc cagggaccga agtgactgtc    300

taggagagca tttgtatgtt atggtgaatg ccaaatttga agaacaagga cagggggaca    360

tccctacatt ttacacctat gaagaaggat tatcccatct aacagcagaa ggccaagcca    420

cactggagag attagaagga atgctttctc agtctgtgag cagccagtat aatatggctg    480

gggtcaggac agaagattca ataagagatt atgaagatgg gatggaggtg gataccacac    540

caacagttgc tggacagttt gaggatgcag atgttgatca ctgaaaatga tttatgcaag    600

tttaagattc tgctcctaag tgtaggagag aacttggtgc ctcttccact ctggagtgaa    660

gttaatgaaa gtctttttcc ttttccaaaa cccaacctga accagttctt tcttgagaca    720

gactatactg agacaacaag ttgtcaccag cagaagatag ataatatgac ctttattaac    780

ttgatgaatt aacttaacca agagggtatt tgtagtttac tatttaccct aaaactttct    840

gtgtctgggt accctctgag taggcctata attcctacct tgactgtgtg catcatttgt    900

aagctagcag atctatgtgg tgaaaatgca caggagcttg gtagactgcg ggggaaagag    960

agagctcctt tcgccatgtt ttaccagtct gctgttataa cctcttaggt tgtatccttt   1020

aatttccagc cttttaggtt agtttctgta acagaacaag tgagtctggg atgaagtcct   1080

caaagtactt caaatggtaa ttgttttgtt tttgtaatag cttaacaaat aaacctaggt   1140

tttctatatt actttgctct cattcttgac taaaaccatt aatgagaaat gttttttaaa   1200

aaataatgct ggcaaatatg agaattttgt tggctttatt tttgtttact tgttgagaag   1260

atgaacatga aattaataag aaaatatagt tatagcttct ggcaagtatt tagtaaggca   1320

aagatttaac acatttcagg ggatttctgc cacttccttt tagatcagca gtaatttctt   1380

atatttatca actctcaatt tttagttttc atagatacct gggtattata aggctgattt   1440

gtaattactg atttatactt ggacttttga aatcattatg tgtccttaaa aataaggtta   1500

tacaagctaa ccttcttaac aggatcacat ggctaattag tgactaaact gatgtttggt   1560

accactcagc ccagtgttca tttcagcact gtcacttggt ttcccttatc ttgcaaggta   1620

gactgaaaaa aaacgaattt tcctttttct aaccagactc tcagaatttc tgagtctgtt   1680

aacaataggc aagtaaaaca gccacttgaa atggaaacta aaatttactg agacctctgt   1740

actagccact gtcctgagtt ctttattatg tattataata ttcttaatta tcttatgaga   1800

tacgctttta tcccacttta tagttgagga aactgagtta tagagagagg taaaataact   1860

tgcttaaggt catgtagata gtgaattgtg atttttgagc ctgtgcttta aaacatcata   1920

cagccttacc acctaccagc agcagaaagc atgcacactc tccccactgc tgcagggttt   1980

cagtgttaac atttcaatgg ccagtacaag agcttcccca gtttctctgc tacccatctg   2040

agcaacaccc ataattctat cctagaagtt tgtccattct tcagtaatca gtcaggacat   2100

tctcacaggc taatattaga aattccattt gagttccttt taaaaggaac aaatttataa   2160

ttgtgacttt ccatgaacat aaattgctct gatagcaaaa tgtcgagaag attcagagtg   2220

tacttggttt cttgttggtg ttgctgtggt caatgcaata tgcaaaaagg caggagacca   2280

aagcatgtgg gcacctctct gggcttattt cctcattaga ctaagtgact ttcaaagatt   2340

gagctgtaac attcactaga tagttagaac cgtagcattg agaaaataga agctgagaaa   2400

aaagagcagg tcaggctttt aaaagataaa atttataatg atcagccaga caatatttat   2460

tg                                                                  2462


<210>  7971
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7971

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Gln Gly Gln Gly Asp Ile Pro Thr 
                85                  90                  95


Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His Leu Thr Ala Glu Gly Gln 
            100                 105                 110


Ala Thr Leu Glu Arg Leu Glu Gly Met Leu Ser Gln Ser Val Ser Ser 
        115                 120                 125


Gln Tyr Asn Met Ala Gly Val Arg Thr Glu Asp Ser Ile Arg Asp Tyr 
    130                 135                 140


Glu Asp Gly Met Glu Val Asp Thr Thr Pro Thr Val Ala Gly Gln Phe 
145                 150                 155                 160


Glu Asp Ala Asp Val Asp His 
                165


<210>  7972
<211>  2510
<212>  DNA
<213>  Homo sapiens

<400>  7972
cggggtgact gcctcttcca gggcgggcgg tgtggtgcac gcattgctgt gctccaactc     60

cctcagggcc tgtgttgccg cactctgctg ctatgagctt cctcaaaagt ttcccgccgc    120

ctgggccagc ggaggggctc ctgcggcagc agccagacac tgaggctgtg ctgaacggga    180

agggcctcgg cactggtacc ctttacatcg ctgagagccg cctgtcttgg ttagatggct    240

ctggattagg attctcactg gaatacccca ccattagttt acatgcatta tccagggacc    300

gaagtgactg tctaggagag catttgtatg ttatggtgaa tgccaaattt gaagaagaat    360

caaaagaacc tgttgctgat gaagaagagg aagacagtga tgatgatgtt gaacctatta    420

ctgaatttag atttgtgcct agtgataaat cagcgttgga ggcaatgttc actgcaatgt    480

gcgaatgcca ggccttgcat ccagatcctg aggatgagga ttcagatgac tacgatggag    540

aagaatatga tgtggaagca catgatggga tggaggtgga taccacacca acagttgctg    600

gacagtttga ggatgcagat gttgatcact gaaaatgatt tatgcaagtt taagattctg    660

ctcctaagtg taggagagaa cttggtgcct cttccactct ggagtgaagt taatgaaagt    720

ctttttcctt ttccaaaacc caacctgaac cagttctttc ttgagacaga ctatactgag    780

acaacaagtt gtcaccagca gaagatagat aatatgacct ttattaactt gatgaattaa    840

cttaaccaag agggtatttg tagtttacta tttaccctaa aactttctgt gtctgggtac    900

cctctgagta ggcctataat tcctaccttg actgtgtgca tcatttgtaa gctagcagat    960

ctatgtggtg aaaatgcaca ggagcttggt agactgcggg ggaaagagag agctcctttc   1020

gccatgtttt accagtctgc tgttataacc tcttaggttg tatcctttaa tttccagcct   1080

tttaggttag tttctgtaac agaacaagtg agtctgggat gaagtcctca aagtacttca   1140

aatggtaatt gttttgtttt tgtaatagct taacaaataa acctaggttt tctatattac   1200

tttgctctca ttcttgacta aaaccattaa tgagaaatgt tttttaaaaa ataatgctgg   1260

caaatatgag aattttgttg gctttatttt tgtttacttg ttgagaagat gaacatgaaa   1320

ttaataagaa aatatagtta tagcttctgg caagtattta gtaaggcaaa gatttaacac   1380

atttcagggg atttctgcca cttcctttta gatcagcagt aatttcttat atttatcaac   1440

tctcaatttt tagttttcat agatacctgg gtattataag gctgatttgt aattactgat   1500

ttatacttgg acttttgaaa tcattatgtg tccttaaaaa taaggttata caagctaacc   1560

ttcttaacag gatcacatgg ctaattagtg actaaactga tgtttggtac cactcagccc   1620

agtgttcatt tcagcactgt cacttggttt cccttatctt gcaaggtaga ctgaaaaaaa   1680

acgaattttc ctttttctaa ccagactctc agaatttctg agtctgttaa caataggcaa   1740

gtaaaacagc cacttgaaat ggaaactaaa atttactgag acctctgtac tagccactgt   1800

cctgagttct ttattatgta ttataatatt cttaattatc ttatgagata cgcttttatc   1860

ccactttata gttgaggaaa ctgagttata gagagaggta aaataacttg cttaaggtca   1920

tgtagatagt gaattgtgat ttttgagcct gtgctttaaa acatcataca gccttaccac   1980

ctaccagcag cagaaagcat gcacactctc cccactgctg cagggtttca gtgttaacat   2040

ttcaatggcc agtacaagag cttccccagt ttctctgcta cccatctgag caacacccat   2100

aattctatcc tagaagtttg tccattcttc agtaatcagt caggacattc tcacaggcta   2160

atattagaaa ttccatttga gttcctttta aaaggaacaa atttataatt gtgactttcc   2220

atgaacataa attgctctga tagcaaaatg tcgagaagat tcagagtgta cttggtttct   2280

tgttggtgtt gctgtggtca atgcaatatg caaaaaggca ggagaccaaa gcatgtgggc   2340

acctctctgg gcttatttcc tcattagact aagtgacttt caaagattga gctgtaacat   2400

tcactagata gttagaaccg tagcattgag aaaatagaag ctgagaaaaa agagcaggtc   2460

aggcttttaa aagataaaat ttataatgat cagccagaca atatttattg              2510


<210>  7973
<211>  179
<212>  PRT
<213>  Homo sapiens

<400>  7973

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Glu Ser Lys Glu Pro Val Ala Asp 
                85                  90                  95


Glu Glu Glu Glu Asp Ser Asp Asp Asp Val Glu Pro Ile Thr Glu Phe 
            100                 105                 110


Arg Phe Val Pro Ser Asp Lys Ser Ala Leu Glu Ala Met Phe Thr Ala 
        115                 120                 125


Met Cys Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser 
    130                 135                 140


Asp Asp Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Asp Gly Met 
145                 150                 155                 160


Glu Val Asp Thr Thr Pro Thr Val Ala Gly Gln Phe Glu Asp Ala Asp 
                165                 170                 175


Val Asp His 



<210>  7974
<211>  2684
<212>  DNA
<213>  Homo sapiens

<400>  7974
cggggtgact gcctcttcca gggcgggcgg tgtggtgcac gcattgctgt gctccaactc     60

cctcagggcc tgtgttgccg cactctgctg ctatgagctt cctcaaaagt ttcccgccgc    120

ctgggccagc ggaggggctc ctgcggcagc agccagacac tgaggctgtg ctgaacggga    180

agggcctcgg cactggtacc ctttacatcg ctgagagccg cctgtcttgg ttagatggct    240

ctggattagg attctcactg gaatacccca ccattagttt acatgcatta tccagggacc    300

gaagtgactg tctaggagag catttgtatg ttatggtgaa tgccaaattt gaagaagaat    360

caaaagaacc tgttgctgat gaagaagagg aagacagtga tgatgatgtt gaacctatta    420

ctgaatttag atttgtgcct agtgataaat cagcgttgga ggcaatgttc actgcaatgt    480

gcgaatgcca ggccttgcat ccagatcctg aggatgagga ttcagatgac tacgatggag    540

aagaatatga tgtggaagca catgaacaag gacaggggga catccctaca ttttacacct    600

atgaagaagg attatcccat ctaacagcag aaggccaagc cacactggag agattagaag    660

gaatgctttc tcagtctgtg agcagccagt ataatatggc tggggtcagg acagaagatt    720

caataagaga ttatgaagat gggatggagg tggataccac accaacagtt gctggacagt    780

ttgaggatgc agatgttgat cactgaaaat gatttatgca agtttaagat tctgctccta    840

agtgtaggag agaacttggt gcctcttcca ctctggagtg aagttaatga aagtcttttt    900

ccttttccaa aacccaacct gaaccagttc tttcttgaga cagactatac tgagacaaca    960

agttgtcacc agcagaagat agataatatg acctttatta acttgatgaa ttaacttaac   1020

caagagggta tttgtagttt actatttacc ctaaaacttt ctgtgtctgg gtaccctctg   1080

agtaggccta taattcctac cttgactgtg tgcatcattt gtaagctagc agatctatgt   1140

ggtgaaaatg cacaggagct tggtagactg cgggggaaag agagagctcc tttcgccatg   1200

ttttaccagt ctgctgttat aacctcttag gttgtatcct ttaatttcca gccttttagg   1260

ttagtttctg taacagaaca agtgagtctg ggatgaagtc ctcaaagtac ttcaaatggt   1320

aattgttttg tttttgtaat agcttaacaa ataaacctag gttttctata ttactttgct   1380

ctcattcttg actaaaacca ttaatgagaa atgtttttta aaaaataatg ctggcaaata   1440

tgagaatttt gttggcttta tttttgttta cttgttgaga agatgaacat gaaattaata   1500

agaaaatata gttatagctt ctggcaagta tttagtaagg caaagattta acacatttca   1560

ggggatttct gccacttcct tttagatcag cagtaatttc ttatatttat caactctcaa   1620

tttttagttt tcatagatac ctgggtatta taaggctgat ttgtaattac tgatttatac   1680

ttggactttt gaaatcatta tgtgtcctta aaaataaggt tatacaagct aaccttctta   1740

acaggatcac atggctaatt agtgactaaa ctgatgtttg gtaccactca gcccagtgtt   1800

catttcagca ctgtcacttg gtttccctta tcttgcaagg tagactgaaa aaaaacgaat   1860

tttccttttt ctaaccagac tctcagaatt tctgagtctg ttaacaatag gcaagtaaaa   1920

cagccacttg aaatggaaac taaaatttac tgagacctct gtactagcca ctgtcctgag   1980

ttctttatta tgtattataa tattcttaat tatcttatga gatacgcttt tatcccactt   2040

tatagttgag gaaactgagt tatagagaga ggtaaaataa cttgcttaag gtcatgtaga   2100

tagtgaattg tgatttttga gcctgtgctt taaaacatca tacagcctta ccacctacca   2160

gcagcagaaa gcatgcacac tctccccact gctgcagggt ttcagtgtta acatttcaat   2220

ggccagtaca agagcttccc cagtttctct gctacccatc tgagcaacac ccataattct   2280

atcctagaag tttgtccatt cttcagtaat cagtcaggac attctcacag gctaatatta   2340

gaaattccat ttgagttcct tttaaaagga acaaatttat aattgtgact ttccatgaac   2400

ataaattgct ctgatagcaa aatgtcgaga agattcagag tgtacttggt ttcttgttgg   2460

tgttgctgtg gtcaatgcaa tatgcaaaaa ggcaggagac caaagcatgt gggcacctct   2520

ctgggcttat ttcctcatta gactaagtga ctttcaaaga ttgagctgta acattcacta   2580

gatagttaga accgtagcat tgagaaaata gaagctgaga aaaaagagca ggtcaggctt   2640

ttaaaagata aaatttataa tgatcagcca gacaatattt attg                    2684


<210>  7975
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  7975

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Glu Ser Lys Glu Pro Val Ala Asp 
                85                  90                  95


Glu Glu Glu Glu Asp Ser Asp Asp Asp Val Glu Pro Ile Thr Glu Phe 
            100                 105                 110


Arg Phe Val Pro Ser Asp Lys Ser Ala Leu Glu Ala Met Phe Thr Ala 
        115                 120                 125


Met Cys Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser 
    130                 135                 140


Asp Asp Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Glu Gln Gly 
145                 150                 155                 160


Gln Gly Asp Ile Pro Thr Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His 
                165                 170                 175


Leu Thr Ala Glu Gly Gln Ala Thr Leu Glu Arg Leu Glu Gly Met Leu 
            180                 185                 190


Ser Gln Ser Val Ser Ser Gln Tyr Asn Met Ala Gly Val Arg Thr Glu 
        195                 200                 205


Asp Ser Ile Arg Asp Tyr Glu Asp Gly Met Glu Val Asp Thr Thr Pro 
    210                 215                 220


Thr Val Ala Gly Gln Phe Glu Asp Ala Asp Val Asp His 
225                 230                 235


<210>  7976
<211>  1257
<212>  DNA
<213>  Homo sapiens

<400>  7976
tcttccaggg cgggcggtgt ggtgcacgca ttgctgtgct ccaactccct cagggcctgt     60

gttgccgcac tctgctgcta tgagcttcct caaaagtttc ccgccgcctg ggccagcgga    120

ggggctcctg cggcagcagc cagacactga ggctgtgctg aacgggaagg gcctcggcac    180

tggtaccctt tacatcgctg agagccgcct gtcttggtta gatggctctg gattaggatt    240

ctcactggaa taccccacca ttagtttaca tgcattatcc agggaccgaa gtgactgtct    300

aggagagcat ttgtatgtta tggtgaatgc caaatttgaa gtggaggcaa tgttcactgc    360

aatgtgcgaa tgccaggcct tgcatccaga tcctgaggat gaggattcag atgactacga    420

tggagaagaa tatgatgtgg aagcacatga acaaggacag ggggacatcc ctacatttta    480

cacctatgaa gaaggattat cccatctaac agcagaaggc caagccacac tggagagatt    540

agaaggaatg ctttctcagt ctgtgagcag ccagtataat atggctgggg tcaggacaga    600

agattcaata agagattatg aagatgggat ggaggtggat accacaccaa cagttgctgg    660

acagtttgag gatgcagatg ttgatcactg aaaatgattt atgcaagttt aagattctgc    720

tcctaagtgt aggagagaac ttggtgcctc ttccactctg gagtgaagtt aatgaaagtc    780

tttttccttt tccaaaaccc aacctgaacc agttctttct tgagacagac tatactgaga    840

caacaagttg tcaccagcag aagatagata atatgacctt tattaacttg atgaattaac    900

ttaaccaaga gggtatttgt agtttactat ttaccctaaa actttctgtg tctgggtacc    960

ctctgagtag gcctataatt cctaccttga ctgtgtgcat catttgtaag ctagcagatc   1020

tatgtggtga aaatgcacag gagcttggta gactgcgggg gaaagagaga gctcctttcg   1080

ccatgtttta ccagtctgct gttataacct cttaggttgt atcctttaat ttccagcctt   1140

ttaggttagt ttctgtaaca gaacaagtga gtctgggatg aagtcctcaa agtacttcaa   1200

atggtaattg ttttgttttt gtaatagctt aacaaataaa cctaggtttt ctatatt      1257


<210>  7977
<211>  203
<212>  PRT
<213>  Homo sapiens

<400>  7977

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Val Glu Ala Met Phe Thr Ala Met Cys 
                85                  90                  95


Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser Asp Asp 
            100                 105                 110


Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Glu Gln Gly Gln Gly 
        115                 120                 125


Asp Ile Pro Thr Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His Leu Thr 
    130                 135                 140


Ala Glu Gly Gln Ala Thr Leu Glu Arg Leu Glu Gly Met Leu Ser Gln 
145                 150                 155                 160


Ser Val Ser Ser Gln Tyr Asn Met Ala Gly Val Arg Thr Glu Asp Ser 
                165                 170                 175


Ile Arg Asp Tyr Glu Asp Gly Met Glu Val Asp Thr Thr Pro Thr Val 
            180                 185                 190


Ala Gly Gln Phe Glu Asp Ala Asp Val Asp His 
        195                 200


<210>  7978
<211>  1150
<212>  DNA
<213>  Homo sapiens

<400>  7978
ctcttccagg gcgggcggtg tggtgcacgc attgctgtgc tccaactccc tcagggcctg     60

tgttgccgca ctctgctgct atgagcttcc tcaaaagttt cccgccgcct gggccagcgg    120

aggggctcct gcggcagcag ccagacactg aggctgtgct gaacgggaag ggcctcggca    180

ctggtaccct ttacatcgct gagagccgcc tgtcttggtt agatggctct ggattaggat    240

tctcactgga ataccccacc attagtttac atgcattatc cagggaccga agtgactgtc    300

taggagagca tttgtatgtt atggtgaatg ccaaatttga agaacaagga cagggggaca    360

tccctacatt ttacacctat gaagaaggat tatcccatct aacagcagaa ggccaagcca    420

cactggagag attagaagga atgctttctc agtctgtgag cagccagtat aatatggctg    480

gggtcaggac agaagattca ataagagatt atgaagatgg gatggaggtg gataccacac    540

caacagttgc tggacagttt gaggatgcag atgttgatca ctgaaaatga tttatgcaag    600

tttaagattc tgctcctaag tgtaggagag aacttggtgc ctcttccact ctggagtgaa    660

gttaatgaaa gtctttttcc ttttccaaaa cccaacctga accagttctt tcttgagaca    720

gactatactg agacaacaag ttgtcaccag cagaagatag ataatatgac ctttattaac    780

ttgatgaatt aacttaacca agagggtatt tgtagtttac tatttaccct aaaactttct    840

gtgtctgggt accctctgag taggcctata attcctacct tgactgtgtg catcatttgt    900

aagctagcag atctatgtgg tgaaaatgca caggagcttg gtagactgcg ggggaaagag    960

agagctcctt tcgccatgtt ttaccagtct gctgttataa cctcttaggt tgtatccttt   1020

aatttccagc cttttaggtt agtttctgta acagaacaag tgagtctggg atgaagtcct   1080

caaagtactt caaatggtaa ttgttttgtt tttgtaatag cttaacaaat aaacctaggt   1140

tttctatatt                                                          1150


<210>  7979
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  7979

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Gln Gly Gln Gly Asp Ile Pro Thr 
                85                  90                  95


Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His Leu Thr Ala Glu Gly Gln 
            100                 105                 110


Ala Thr Leu Glu Arg Leu Glu Gly Met Leu Ser Gln Ser Val Ser Ser 
        115                 120                 125


Gln Tyr Asn Met Ala Gly Val Arg Thr Glu Asp Ser Ile Arg Asp Tyr 
    130                 135                 140


Glu Asp Gly Met Glu Val Asp Thr Thr Pro Thr Val Ala Gly Gln Phe 
145                 150                 155                 160


Glu Asp Ala Asp Val Asp His 
                165


<210>  7980
<211>  1372
<212>  DNA
<213>  Homo sapiens

<400>  7980
cggggtgact gcctcttcca gggcgggcgg tgtggtgcac gcattgctgt gctccaactc     60

cctcagggcc tgtgttgccg cactctgctg ctatgagctt cctcaaaagt ttcccgccgc    120

ctgggccagc ggaggggctc ctgcggcagc agccagacac tgaggctgtg ctgaacggga    180

agggcctcgg cactggtacc ctttacatcg ctgagagccg cctgtcttgg ttagatggct    240

ctggattagg attctcactg gaatacccca ccattagttt acatgcatta tccagggacc    300

gaagtgactg tctaggagag catttgtatg ttatggtgaa tgccaaattt gaagaagaat    360

caaaagaacc tgttgctgat gaagaagagg aagacagtga tgatgatgtt gaacctatta    420

ctgaatttag atttgtgcct agtgataaat cagcgttgga ggcaatgttc actgcaatgt    480

gcgaatgcca ggccttgcat ccagatcctg aggatgagga ttcagatgac tacgatggag    540

aagaatatga tgtggaagca catgaacaag gacaggggga catccctaca ttttacacct    600

atgaagaagg attatcccat ctaacagcag aaggccaagc cacactggag agattagaag    660

gaatgctttc tcagtctgtg agcagccagt ataatatggc tggggtcagg acagaagatt    720

caataagaga ttatgaagat gggatggagg tggataccac accaacagtt gctggacagt    780

ttgaggatgc agatgttgat cactgaaaat gatttatgca agtttaagat tctgctccta    840

agtgtaggag agaacttggt gcctcttcca ctctggagtg aagttaatga aagtcttttt    900

ccttttccaa aacccaacct gaaccagttc tttcttgaga cagactatac tgagacaaca    960

agttgtcacc agcagaagat agataatatg acctttatta acttgatgaa ttaacttaac   1020

caagagggta tttgtagttt actatttacc ctaaaacttt ctgtgtctgg gtaccctctg   1080

agtaggccta taattcctac cttgactgtg tgcatcattt gtaagctagc agatctatgt   1140

ggtgaaaatg cacaggagct tggtagactg cgggggaaag agagagctcc tttcgccatg   1200

ttttaccagt ctgctgttat aacctcttag gttgtatcct ttaatttcca gccttttagg   1260

ttagtttctg taacagaaca agtgagtctg ggatgaagtc ctcaaagtac ttcaaatggt   1320

aattgttttg tttttgtaat agcttaacaa ataaacctag gttttctata tt           1372


<210>  7981
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  7981

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Glu Ser Lys Glu Pro Val Ala Asp 
                85                  90                  95


Glu Glu Glu Glu Asp Ser Asp Asp Asp Val Glu Pro Ile Thr Glu Phe 
            100                 105                 110


Arg Phe Val Pro Ser Asp Lys Ser Ala Leu Glu Ala Met Phe Thr Ala 
        115                 120                 125


Met Cys Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser 
    130                 135                 140


Asp Asp Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Glu Gln Gly 
145                 150                 155                 160


Gln Gly Asp Ile Pro Thr Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His 
                165                 170                 175


Leu Thr Ala Glu Gly Gln Ala Thr Leu Glu Arg Leu Glu Gly Met Leu 
            180                 185                 190


Ser Gln Ser Val Ser Ser Gln Tyr Asn Met Ala Gly Val Arg Thr Glu 
        195                 200                 205


Asp Ser Ile Arg Asp Tyr Glu Asp Gly Met Glu Val Asp Thr Thr Pro 
    210                 215                 220


Thr Val Ala Gly Gln Phe Glu Asp Ala Asp Val Asp His 
225                 230                 235


<210>  7982
<211>  1198
<212>  DNA
<213>  Homo sapiens

<400>  7982
cggggtgact gcctcttcca gggcgggcgg tgtggtgcac gcattgctgt gctccaactc     60

cctcagggcc tgtgttgccg cactctgctg ctatgagctt cctcaaaagt ttcccgccgc    120

ctgggccagc ggaggggctc ctgcggcagc agccagacac tgaggctgtg ctgaacggga    180

agggcctcgg cactggtacc ctttacatcg ctgagagccg cctgtcttgg ttagatggct    240

ctggattagg attctcactg gaatacccca ccattagttt acatgcatta tccagggacc    300

gaagtgactg tctaggagag catttgtatg ttatggtgaa tgccaaattt gaagaagaat    360

caaaagaacc tgttgctgat gaagaagagg aagacagtga tgatgatgtt gaacctatta    420

ctgaatttag atttgtgcct agtgataaat cagcgttgga ggcaatgttc actgcaatgt    480

gcgaatgcca ggccttgcat ccagatcctg aggatgagga ttcagatgac tacgatggag    540

aagaatatga tgtggaagca catgatggga tggaggtgga taccacacca acagttgctg    600

gacagtttga ggatgcagat gttgatcact gaaaatgatt tatgcaagtt taagattctg    660

ctcctaagtg taggagagaa cttggtgcct cttccactct ggagtgaagt taatgaaagt    720

ctttttcctt ttccaaaacc caacctgaac cagttctttc ttgagacaga ctatactgag    780

acaacaagtt gtcaccagca gaagatagat aatatgacct ttattaactt gatgaattaa    840

cttaaccaag agggtatttg tagtttacta tttaccctaa aactttctgt gtctgggtac    900

cctctgagta ggcctataat tcctaccttg actgtgtgca tcatttgtaa gctagcagat    960

ctatgtggtg aaaatgcaca ggagcttggt agactgcggg ggaaagagag agctcctttc   1020

gccatgtttt accagtctgc tgttataacc tcttaggttg tatcctttaa tttccagcct   1080

tttaggttag tttctgtaac agaacaagtg agtctgggat gaagtcctca aagtacttca   1140

aatggtaatt gttttgtttt tgtaatagct taacaaataa acctaggttt tctatatt     1198


<210>  7983
<211>  179
<212>  PRT
<213>  Homo sapiens

<400>  7983

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Glu Ser Lys Glu Pro Val Ala Asp 
                85                  90                  95


Glu Glu Glu Glu Asp Ser Asp Asp Asp Val Glu Pro Ile Thr Glu Phe 
            100                 105                 110


Arg Phe Val Pro Ser Asp Lys Ser Ala Leu Glu Ala Met Phe Thr Ala 
        115                 120                 125


Met Cys Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser 
    130                 135                 140


Asp Asp Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Asp Gly Met 
145                 150                 155                 160


Glu Val Asp Thr Thr Pro Thr Val Ala Gly Gln Phe Glu Asp Ala Asp 
                165                 170                 175


Val Asp His 



<210>  7984
<211>  970
<212>  DNA
<213>  Homo sapiens

<400>  7984
cggggtgact gcctcttcca gggcgggcgg tgtggtgcac gcattgctgt gctccaactc     60

cctcagggcc tgtgttgccg cactctgctg ctatgagctt cctcaaaagt ttcccgccgc    120

ctgggccagc ggaggggctc ctgcggcagc agccagacac tgaggctgtg ctgaacggga    180

agggcctcgg cactggtacc ctttacatcg ctgagagccg cctgtcttgg ttagatggct    240

ctggattagg attctcactg gaatacccca ccattagttt acatgcatta tccagggacc    300

gaagtgactg tctaggagag catttgtatg ttatggtgaa tgccaaattt gaagaagaat    360

caaaagaacc tgttgctgat gaagaagagg aagacagtga tgatgatgtt gaacctatta    420

ctgaatttag atttgtgcct agtgataaat cagcgttgga ggcaatgttc actgcaatgt    480

gcgaatgcca ggccttgcat ccagatcctg aggatgagga ttcagatgac tacgatggag    540

aagaatatga tgtggaagca catgaacaag gacaggggga catccctaca ttttacacct    600

atgaagaagg attatcccat ctaacagcag aaggccaagc cacactggag agattagaag    660

gaatgctttc tcagtctgtg agcagccagt ataatatggc tggggtcagg acagaagatt    720

caataagaga ttatgaagat gggatggagg tggataccac accaacagtt gctggacagt    780

ttgaggatgc agatgttgat cactgaaaat gatttatgca agtttaagaa accagccttt    840

taaagttcca gttagcttcc aagttactgc tattgtgaaa actgtataac attgcttctt    900

atactgacca tgaattgtga tactggacct gtgctttctt ctcacatcct gccagtggaa    960

ctatcagaaa                                                           970


<210>  7985
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  7985

Met Ser Phe Leu Lys Ser Phe Pro Pro Pro Gly Pro Ala Glu Gly Leu 
1               5                   10                  15


Leu Arg Gln Gln Pro Asp Thr Glu Ala Val Leu Asn Gly Lys Gly Leu 
            20                  25                  30


Gly Thr Gly Thr Leu Tyr Ile Ala Glu Ser Arg Leu Ser Trp Leu Asp 
        35                  40                  45


Gly Ser Gly Leu Gly Phe Ser Leu Glu Tyr Pro Thr Ile Ser Leu His 
    50                  55                  60


Ala Leu Ser Arg Asp Arg Ser Asp Cys Leu Gly Glu His Leu Tyr Val 
65                  70                  75                  80


Met Val Asn Ala Lys Phe Glu Glu Glu Ser Lys Glu Pro Val Ala Asp 
                85                  90                  95


Glu Glu Glu Glu Asp Ser Asp Asp Asp Val Glu Pro Ile Thr Glu Phe 
            100                 105                 110


Arg Phe Val Pro Ser Asp Lys Ser Ala Leu Glu Ala Met Phe Thr Ala 
        115                 120                 125


Met Cys Glu Cys Gln Ala Leu His Pro Asp Pro Glu Asp Glu Asp Ser 
    130                 135                 140


Asp Asp Tyr Asp Gly Glu Glu Tyr Asp Val Glu Ala His Glu Gln Gly 
145                 150                 155                 160


Gln Gly Asp Ile Pro Thr Phe Tyr Thr Tyr Glu Glu Gly Leu Ser His 
                165                 170                 175


Leu Thr Ala Glu Gly Gln Ala Thr Leu Glu Arg Leu Glu Gly Met Leu 
            180                 185                 190


Ser Gln Ser Val Ser Ser Gln Tyr Asn Met Ala Gly Val Arg Thr Glu 
        195                 200                 205


Asp Ser Ile Arg Asp Tyr Glu Asp Gly Met Glu Val Asp Thr Thr Pro 
    210                 215                 220


Thr Val Ala Gly Gln Phe Glu Asp Ala Asp Val Asp His 
225                 230                 235


<210>  7986
<211>  8556
<212>  DNA
<213>  Homo sapiens

<400>  7986
ctggtttatc aacttgacga gaatcatttc aaaattttag gaaaaaaatt tatgtctcag     60

taaaactttg tttagaatta ggtttttcag tagcaaggat aaggtgaagg gattaaaaat    120

gtacgtaaaa ttagtagtca atgaattctg gaatgcagtc tgtataatcc tattcagaga    180

ttatgctatt tactgaatat agctttggtt gtgtttaaat ctgcactagt attaggtgct    240

ccttaaaagt tgaaaatata tagccaataa ggtataaaga agaattgaca gataaatcta    300

aacagtttct ttgtatagta ctaacttctg aaatgttcag tggtggcatt tgataaagta    360

agttgtaata tgatcacatt gaggaatgtt atataattat taaactcaat ttttataaaa    420

ggcatcattt tataaaagta tcataagaaa gtgccaatgt ttcaatgaat aaattgaggc    480

aacatgatac caacttagtg aaaaatatac aagaccagaa ggaagtaacc taaaatatta    540

ctagtgattg cctctgggta ataggatatg ggctttttgt ctttctatat ttttcatttt    600

cccactgccg tgttcctggt acctcagtga aatgaagtgc tcagttcttt taacagttgt    660

cagtttttaa aacaaatata gtcttctgga aatgttttag gtagcatttt caattttatg    720

tttttaagcc atctcttgaa tttgaataaa ttatttgaac tgcataaata tttgcaatcc    780

attgagaaca ccaaaacaaa aagtaaaaag cagaaaccta aatttttcta aatttttttt    840

aatatctaga agttgtatct caaagttttt gtaattttct tcattgtcag attttatttt    900

ttactgtcaa atatccaatg acagaggcca cctcttttaa aatagaaact ttaaatggaa    960

atatacatta tactaagtct tatattttat agccttgaaa gtttctattc atgtaattaa   1020

gctttttctg atttttagag gaacagaaag aaagtgaaaa gatgaaaagt gaggagcagc   1080

ctatggattt agaaaaccgt tctacagcca atgttctaga agagactact gtgaaaaaag   1140

aaaaagaaga tgaaaaggaa cttgtgaaac tgccagtcat agtgaagcta gaaaaacctt   1200

tgccagaaaa tgaagaaaaa aagattatca aagaagaaag tgattccttc aaggaaaatg   1260

tcaaacccat taaagttgag gtgaaggaat gtagagcaga tcctaaagat accaaaagta   1320

gcatggagaa gccagtggca caggagcctg aaaggatcga atttggtggc aatattaaat   1380

cttctcacga aattactgag aaatctactg aagaaactga gaaacttaaa aatgaccagc   1440

aggccaagat accactaaaa aaacgagaaa ttaaactgag tgatgatttt gacagtccag   1500

tcaagggacc tttgtgtaaa tcagttactc caacaaaaga gtttttgaaa gatgaaataa   1560

aacaagagga agagacttgt aaaaggatct ctacaatcac tgctttgggt catgaaggga   1620

aacagctggt aaatggagaa gttagtgatg aaagggtagc tccaaatttt aagacagaac   1680

caatagagac aaagttttat gagacaaagg aagagagcta tagcccctct aaggacagaa   1740

atatcatcac ggagggaaat ggaacagagt ccttaaattc tgtcataaca agtatgaaaa   1800

caggtgagct tgagaaagaa acagcccctt tgaggaaaga tgcagatagt tcaatatcag   1860

tcttagagat ccatagtcaa aaagcacaaa tagaggaacc cgatcctcca gaaatggaaa   1920

cttctcttga ttcttctgag atggcaaaag atctctcttc aaaaactgct ttatcttcca   1980

ccgagtcgtg taccatgaaa ggtgaagaga agtctcccaa aactaagaag gataagcgcc   2040

caccaatcct agaatgtctt gaaaagttag agaagtccaa aaagactttt cttgataagg   2100

acgcacaaag attgagtcca ataccagaag aagttccaaa gagtactcta gagtcagaaa   2160

agcctggctc tcctgaggca gctgaaactt ctccaccatc taatatcatt gaccactgtg   2220

agaaactagc ctcagaaaaa gaagtggtag aatgccagag tacaagtact gttggtggcc   2280

agtctgtgaa aaaagtagac ctagaaaccc taaaagagga ttctgagttc acaaaggtag   2340

aaatggataa tctggacaat gcccagacct ctggcataga ggagccttct gagacaaagg   2400

gttctatgca aaaaagcaaa ttcaaatata agttggttcc tgaagaagaa accactgcct   2460

cagaaaatac agagataacc tctgaaaggc agaaagaggg catcaaatta acaatcagga   2520

tatcaagtcg gaaaaagaag cccgattctc cccccaaagt tctagaacca gaaaacaagc   2580

aagagaagac agaaaaggaa gaggagaaaa caaatgtggg tcgtacttta agaagatctc   2640

caagaatatc tagacccact gcaaaagtgg ctgagatcag agatcagaaa gctgataaaa   2700

aaagagggga aggagaagat gaggtggaag aagagtcaac agctttgcaa aaaactgaca   2760

aaaaggaaat tttgaaaaaa tcagagaaag atacaaattc taaagtaagc aaggtaaaac   2820

ccaaaggcaa agttcgatgg actggttctc ggacacgtgg cagatggaaa tattccagca   2880

atgatgaaag tgaagggtct ggcagtgaaa aatcatctgc agcttcagaa gaggaggaag   2940

aaaaggaaag tgaagaagcc atcctagcag atgatgatga accatgcaaa aaatgtggcc   3000

ttccaaacca tcctgagcta attcttctgt gtgactcttg cgatagtgga taccatactg   3060

cctgccttcg ccctcctctg atgatcatcc cagatggaga atggttctgc ccaccttgcc   3120

aacataaact gctctgtgaa aaattagagg aacagttgca ggatttggat gttgccttaa   3180

agaagaaaga gcgtgccgaa cgaagaaaag aacgcttggt gtatgttggt atcagtattg   3240

aaaacatcat tcctccacaa gagccagact tttctgaaga tcaagaagaa aagaaaaaag   3300

attcaaaaaa atccaaagca aacttgcttg aaaggaggtc aacaagaaca aggaaatgta   3360

taagctacag atttgatgag tttgatgaag caattgatga agctattgaa gatgacatca   3420

aagaagccga tggaggagga gttggccgag gaaaagatat ctccaccatc acaggtcatc   3480

gtgggaaaga catctctact attttggatg aagaaagaaa agaaaataaa cgaccccaga   3540

gggcagctgc tgctcgaagg aagaaacgcc ggcgattaaa tgatctggac agtgatagca   3600

acctggatga agaagagagc gaggatgaat tcaagatcag tgatggatct caagatgagt   3660

ttgttgtgtc tgatgaaaac ccagatgaaa gtgaagaaga tccgccatct aatgatgaca   3720

gtgacactga cttttgtagc cgtagactga ggcgacaccc ctctcggcca atgaggcaga   3780

gcaggcgttt gcgaagaaag accccaaaga aaaaatattc cgatgatgat gaagaggagg   3840

aatctgagga gaatagtaga gactctgaaa gtgacttcag tgatgatttt agtgatgatt   3900

ttgtagaaac tcggcgaagg cggtcaagga gaaatcagaa aagacaaatt aactacaaag   3960

aagactcaga aagtgacggt tcccagaaga gtttgcgacg tggtaaagaa ataaggcgag   4020

tacacaagcg aagactttcc agctcagaga gtgaagagag ctatttgtcc aagaactctg   4080

aagatgatga gctagctaaa gaatcaaagc ggtcagttcg aaagcggggc cgaagcacag   4140

acgagtattc agaagcagat gaggaggagg aggaagagga aggcaaacca tcccgcaaac   4200

ggctacaccg gattgagacg gatgaggagg agagttgtga caatgctcat ggagatgcaa   4260

atcagcctgc ccgtgacagc cagcctaggg tcctgccctc agaacaagag agcaccaaga   4320

agccctaccg gatagaaagt gatgaggaag aggactttga aaatgtaggc aaagtgggga   4380

gcccattgga ctatagctta gtggacttac cttcaaccaa tggacagagc cctggcaaag   4440

ccattgagaa cttgattggc aagcctactg agaagtctca gacccccaag gacaacagca   4500

cagccagtgc aagcctagcc tccaatggga caagtggtgg gcaggaggca ggagcaccag   4560

aagaggagga agatgagctt ttgagagtga ctgaccttgt tgattatgtc tgtaacagtg   4620

aacagttata agactttttt tccatttttg tgctaattta ttccacggta gctctcacac   4680

cagcgggcca gttattaaaa gctgtttaat ttttcctaga aaactccact acagaatgac   4740

ttttagaaga aaaatttcaa caaatcctga agtctttctg tgaagtgacc agttctgaac   4800

tttgaagata aataattgct gtaaattcct tttgattttc tttttccagg ttcatggtcc   4860

ttggtaattt cattcatgga aaaaaatctt attataataa caacaaagat ttgtatattt   4920

ttgactttat atttcctgag ctctcctgac tttgtgaaaa agggtggatg aaaatgcatt   4980

ccgaatctgt gagggcccaa aacagaattt aggggtgggt gaaagcactt gtgctttagc   5040

tttttcatat taaatatata ttatatttaa acattcatgg catagatgat gatttacaga   5100

caatttaaaa gttcaagtct gtactgttac agtttgagaa ttgtagataa catcatacat   5160

aagtcattta gtaacagcct ttgtgaaatg aacttgttta ctattggaga taaccacact   5220

taataaagaa gagacagtga aagtaccatc ataattaacc taaatttttg ttatagcaga   5280

gtttcttgtt taaaaaaaaa taaaatcatc tgaaaagcat ttgtacagta aaatgtataa   5340

tgaagctttg ccaaccagac tgtgctagca acaaattttt ttaaataagc tttatgcagt   5400

ggtaataagg tggcctcaaa tatattgtgt ctgatggaga gttattagtg aaatgaatgt   5460

ggtctttctt aaggcctggg tggactgtaa actttgccaa tagtataact cttgtcttct   5520

ggccacttga tgtttaaata tctgaaatat cattttgaaa aaaatacatc tatatataac   5580

atacatgaag agatgctaag ctgacagtga tattttagca catttgaaga ctgggaagag   5640

attttcaggt gaattttaac tggtctattc ttgcccttag tatctacttc aaattgaagt   5700

ctacaaacaa agcagttcct ttgggaggtt tttagtttga gttttagcgt gtgtgtgtgt   5760

ttgtgtgtgt gcgtgtgcgt gtgtgtgtgt gttggaattt cctatctgcc tggatatatt   5820

agcagagttt gaatgtagtt ttggcctttg gccattagac ttctattaaa attcattaat   5880

agtcatacaa ccaacataga gttgaatgag aactgccgat gtaattaata ggcatgacat   5940

ccatttcaaa catctcaaca ctttaaagaa aagccctttg tttcaagaaa aaagggtttg   6000

taactaacta aatacctaac atgtaattga cactaaaata tgaactttgt cttatttagt   6060

ttctgttata gctgtaaaat ttcaggcaga gccataacat tgtacagagt gtagcacttg   6120

tgattaaacc tagcctgtta aatcctgaaa ccttcaacca ttacttctgt gaatacttta   6180

gccctgggat ttgggttttt ctgttccggt gttgtgtctg ttgccggcaa tggacacacc   6240

atatctgctg ctggcccaag gaacgtcatt aatttttctt tccaaattaa gtattatgtg   6300

ctagtcagtg tatagtaaag cacttctctt ttttattact aaaaagctgg cattagattt   6360

gcattataaa tacctctcta ggaactttat actccttttc cttcttcaac aggtattgcc   6420

cttaaatctt atcttttggc cttgaaagtt tatagctatt gtttttcagt tgttcgttgt   6480

tttgttttgt ttcactttag ttctgtagta cctgcccatt aatatttttg ctttgattct   6540

agcaatgtgt atgtatctgt ataaaaaata aaataatgaa agcaacctaa aaataggatg   6600

caccaatagc atgtggttcc aagtaagttg tgatttttat tttgagacag tgttccactg   6660

gaagggaggg aagggcttac attcacagac agtaaagcag ggctgtgtaa ggagctacat   6720

ttacttaaca gtctcctttc cagctaggtt tgttttattt atttgcaagt cagctaagaa   6780

ttaacctttt aaaccatcta aaacaggcaa gcaatataaa gatttctact agtgcaaggt   6840

aagtggtttg aatatacaag tgccctttcc tgccacccag tctcactacc gttttagtcc   6900

tgcagctggg taaagccact attgtgtgga aactctccca tgtgccctgt ctctacctct   6960

ggacacacca gctccttctt ccacctattc tattcctcag ttaagccaag tgatcagaag   7020

tagtattaaa tgggtagata attttaacag gatgcctaat gtgaaataag gagttatttt   7080

tactcttcta ctatagaaag cctaaggtaa ttcttaccat ctcaaagact gagtattcca   7140

tttaggtttg gagaccactt gtgctgtgct gcctgatatt taccaaactt gaataagtgt   7200

tcgtcaactt gatagtgaat gtaccccttc tcaccttata ttttgattaa atcaattaac   7260

tataggtcat ctaccaagaa tgtaatccaa gcggttgata aaacattatt aggcagatag   7320

attattgatt attaaatttt gagcagtgca aaaacggttt tgctgcttgg agttcagatt   7380

cagtccctca aagagtttat gatcactgaa atacactctg aaggtattct gaagaagtta   7440

aaaaatttta gaaaacgaaa tgttctgtat acaaagacaa tacagtcact acgaactgca   7500

gaaagtatag gaaagcagta attgatgtag agtttagaca gtcttggatc ttttttagag   7560

cactaaccat ggatttagac tcaaaatagc tgctacataa tagagccctt taataattta   7620

aacccccctt gttgaaatac aagttggact cccagtgtca aactctagac tgtagctaat   7680

gtattaaagg gagatgtaga ttaatattca gtatatttag tttgcaattt ctgaaaaggt   7740

ttgaaaacta gtcagctttt cacacagcag aagctttgaa ctgaaatatg tgtgaaaagg   7800

acgcagactg aaaacgtttt ggttttgtac atcagtgctg atgaaattag tgtaaaacat   7860

tttccatcat tggcacatta ctgcaaaatg atggcagaga tattttcaag aatgtacatc   7920

aagttatatt tccttgacat ccttttttca attggtcaag gttacagatt cagaggataa   7980

agggtagttt catttagaat aaattcatgt ctactggcaa tctatatata aaagtgacct   8040

gcccaagaac caaaaacttt aaatgctaat gaagcttttg aaaaataatt tttaaacaaa   8100

ttaattttaa aagggtgtta cacgtaccca gtttttactt tttagttgat gaaacccatc   8160

ctataatata catttgagca aagtacacat attaagaaaa acatggacat ttacttgttt   8220

aatagtcaaa atgatgagga aatgttagct gtttttaagt gggactggtg gggtgtcctt   8280

tgtcacaagg aatgcttttt tagcttgttt gtgggcataa gagatgttaa ccctttgctg   8340

attctaccac acaactgtaa agaacctaat gaatctacaa gtttaatatt cagaaaaagc   8400

taggaactcc gctctttacc agtacagtgg aacaggcccg ttattcaagg tgatgcctca   8460

cagctataga acaactattc aaagacccag agttaaatgg tacatgtgta tatgtgtgtg   8520

tgtgtgtgca cacgcacaca cttcagataa gtatca                             8556


<210>  7987
<211>  1189
<212>  PRT
<213>  Homo sapiens

<400>  7987

Met Lys Ser Glu Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala 
1               5                   10                  15


Asn Val Leu Glu Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys 
            20                  25                  30


Glu Leu Val Lys Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro 
        35                  40                  45


Glu Asn Glu Glu Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys 
    50                  55                  60


Glu Asn Val Lys Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp 
65                  70                  75                  80


Pro Lys Asp Thr Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro 
                85                  90                  95


Glu Arg Ile Glu Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr 
            100                 105                 110


Glu Lys Ser Thr Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala 
        115                 120                 125


Lys Ile Pro Leu Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp 
    130                 135                 140


Ser Pro Val Lys Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu 
145                 150                 155                 160


Phe Leu Lys Asp Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile 
                165                 170                 175


Ser Thr Ile Thr Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly 
            180                 185                 190


Glu Val Ser Asp Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile 
        195                 200                 205


Glu Thr Lys Phe Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys 
    210                 215                 220


Asp Arg Asn Ile Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser 
225                 230                 235                 240


Val Ile Thr Ser Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro 
                245                 250                 255


Leu Arg Lys Asp Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser 
            260                 265                 270


Gln Lys Ala Gln Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser 
        275                 280                 285


Leu Asp Ser Ser Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu 
    290                 295                 300


Ser Ser Thr Glu Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys 
305                 310                 315                 320


Thr Lys Lys Asp Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu 
                325                 330                 335


Glu Lys Ser Lys Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser 
            340                 345                 350


Pro Ile Pro Glu Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro 
        355                 360                 365


Gly Ser Pro Glu Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp 
    370                 375                 380


His Cys Glu Lys Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser 
385                 390                 395                 400


Thr Ser Thr Val Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr 
                405                 410                 415


Leu Lys Glu Asp Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp 
            420                 425                 430


Asn Ala Gln Thr Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser 
        435                 440                 445


Met Gln Lys Ser Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr 
    450                 455                 460


Thr Ala Ser Glu Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly 
465                 470                 475                 480


Ile Lys Leu Thr Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser 
                485                 490                 495


Pro Pro Lys Val Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys 
            500                 505                 510


Glu Glu Glu Lys Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg 
        515                 520                 525


Ile Ser Arg Pro Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala 
    530                 535                 540


Asp Lys Lys Arg Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr 
545                 550                 555                 560


Ala Leu Gln Lys Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys 
                565                 570                 575


Asp Thr Asn Ser Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg 
            580                 585                 590


Trp Thr Gly Ser Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp 
        595                 600                 605


Glu Ser Glu Gly Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu 
    610                 615                 620


Glu Glu Glu Lys Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu 
625                 630                 635                 640


Pro Cys Lys Lys Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu 
                645                 650                 655


Cys Asp Ser Cys Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro 
            660                 665                 670


Leu Met Ile Ile Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His 
        675                 680                 685


Lys Leu Leu Cys Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val 
    690                 695                 700


Ala Leu Lys Lys Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val 
705                 710                 715                 720


Tyr Val Gly Ile Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp 
                725                 730                 735


Phe Ser Glu Asp Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys 
            740                 745                 750


Ala Asn Leu Leu Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser 
        755                 760                 765


Tyr Arg Phe Asp Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp 
    770                 775                 780


Asp Ile Lys Glu Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile 
785                 790                 795                 800


Ser Thr Ile Thr Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp 
                805                 810                 815


Glu Glu Arg Lys Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg 
            820                 825                 830


Arg Lys Lys Arg Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu 
        835                 840                 845


Asp Glu Glu Glu Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln 
    850                 855                 860


Asp Glu Phe Val Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp 
865                 870                 875                 880


Pro Pro Ser Asn Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu 
                885                 890                 895


Arg Arg His Pro Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg 
            900                 905                 910


Lys Thr Pro Lys Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser 
        915                 920                 925


Glu Glu Asn Ser Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser 
    930                 935                 940


Asp Asp Phe Val Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys 
945                 950                 955                 960


Arg Gln Ile Asn Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys 
                965                 970                 975


Ser Leu Arg Arg Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu 
            980                 985                 990


Ser Ser Ser Glu Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp 
        995                 1000                1005


Asp Glu Leu Ala Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg 
    1010                1015                1020


Ser Thr Asp Glu Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu 
1025                1030                1035                1040


Gly Lys Pro Ser Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu 
                1045                1050                1055


Glu Ser Cys Asp Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp 
            1060                1065                1070


Ser Gln Pro Arg Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro 
        1075                1080                1085


Tyr Arg Ile Glu Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys 
    1090                1095                1100


Val Gly Ser Pro Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn 
1105                1110                1115                1120


Gly Gln Ser Pro Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr 
                1125                1130                1135


Glu Lys Ser Gln Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu 
            1140                1145                1150


Ala Ser Asn Gly Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu 
        1155                1160                1165


Glu Glu Asp Glu Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys 
    1170                1175                1180


Asn Ser Glu Gln Leu 
1185


<210>  7988
<211>  8550
<212>  DNA
<213>  Homo sapiens

<400>  7988
tttcattccc cctgtcacac gaggcagtgg caagcccgaa ggggaggaga gaagggggcg     60

gaaagagggc ggaaagtgaa aggcgccgag ggccgctctg tctcccgtct gactcggttc    120

tcgactgctc cgggccgccg atgtattgtg ggatcgcgga gccgtccctg agacgctggg    180

atccgcagag gagcccactt gagagcgcct cctgtcgtct gtaaggttgc cttgccatcc    240

ctcggcacca caacttcccc cgccccccca tcgcctcctc ctccatcctc cagttcaaaa    300

tggcgacggc ggcggcagcg gcggcggtga tggctcctcc gggctgcccg ggttcgtgcc    360

ccaacttcgc cgtagtctgc tccttcttgg agcgctacgg gccgctgcta gacctgcctg    420

agttgccgtt ccctgagctg gagcgggtgc tgcaggcgcc gccgccggac gtcggcaacg    480

gagaagtacc aaaagaattg gtggagctcc atttgaagct gatgaggaaa attggcaaat    540

ctgttactgc agacagatgg gaaaaatatt tgatcaagat atgccaagag tttaacagta    600

cctgggcatg ggagatggag aagaagggct atcttgaaat gagtgttgaa tgcaaactag    660

cactcttaaa gtacctctgt gagtgtcagt ttgatgacaa tctcaaattc aagaatatta    720

ttaatgagga ggatgccgat actatgcgtc tccagccaat tggtcgagac aaagatggcc    780

tcatgtactg gtaccaattg gatcaagatc acaatgtcag aatgtacata gaagaacaag    840

atgatcaaga tggctcttca tggaaatgca ttgtcagaaa tcgaaacgag ttggctgaga    900

ctcttgcact cctgaaagca caaattgatc ctgtactatt gaaaaactct agccaacaag    960

acaactcttc tcgggaaagt cccagcttag aggatgagga gactaaaaaa gaggaagaaa   1020

cacctaaaca agaggaacag aaagaaagtg aaaagatgaa aagtgaggag cagcctatgg   1080

atttagaaaa ccgttctaca gccaatgttc tagaagagac tactgtgaaa aaagaaaaag   1140

aagatgaaaa ggaacttgtg aaactgccag tcatagtgaa gctagaaaaa cctttgccag   1200

aaaatgaaga aaaaaagatt atcaaagaag aaagtgattc cttcaaggaa aatgtcaaac   1260

ccattaaagt tgaggtgaag gaatgtagag cagatcctaa agataccaaa agtagcatgg   1320

agaagccagt ggcacaggag cctgaaagga tcgaatttgg tggcaatatt aaatcttctc   1380

acgaaattac tgagaaatct actgaagaaa ctgagaaact taaaaatgac cagcaggcca   1440

agataccact aaaaaaacga gaaattaaac tgagtgatga ttttgacagt ccagtcaagg   1500

gacctttgtg taaatcagtt actccaacaa aagagttttt gaaagatgaa ataaaacaag   1560

aggaagagac ttgtaaaagg atctctacaa tcactgcttt gggtcatgaa gggaaacagc   1620

tggtaaatgg agaagttagt gatgaaaggg tagctccaaa ttttaagaca gaaccaatag   1680

agacaaagtt ttatgagaca aaggaagaga gctatagccc ctctaaggac agaaatatca   1740

tcacggaggg aaatggaaca gagtccttaa attctgtcat aacaagtatg aaaacaggtg   1800

agcttgagaa agaaacagcc cctttgagga aagatgcaga tagttcaata tcagtcttag   1860

agatccatag tcaaaaagca caaatagagg aacccgatcc tccagaaatg gaaacttctc   1920

ttgattcttc tgagatggca aaagatctct cttcaaaaac tgctttatct tccaccgagt   1980

cgtgtaccat gaaaggtgaa gagaagtctc ccaaaactaa gaaggataag cgcccaccaa   2040

tcctagaatg tcttgaaaag ttagagaagt ccaaaaagac ttttcttgat aaggacgcac   2100

aaagattgag tccaatacca gaagaagttc caaagagtac tctagagtca gaaaagcctg   2160

gctctcctga ggcagctgaa acttctccac catctaatat cattgaccac tgtgagaaac   2220

tagcctcaga aaaagaagtg gtagaatgcc agagtacaag tactgttggt ggccagtctg   2280

tgaaaaaagt agacctagaa accctaaaag aggattctga gttcacaaag gtagaaatgg   2340

ataatctgga caatgcccag acctctggca tagaggagcc ttctgagaca aagggttcta   2400

tgcaaaaaag caaattcaaa tataagttgg ttcctgaaga agaaaccact gcctcagaaa   2460

atacagagat aacctctgaa aggcagaaag agggcatcaa attaacaatc aggatatcaa   2520

gtcggaaaaa gaagcccgat tctcccccca aagttctaga accagaaaac aagcaagaga   2580

agacagaaaa ggaagaggag aaaacaaatg tgggtcgtac tttaagaaga tctccaagaa   2640

tatctagacc cactgcaaaa gtggctgaga tcagagatca gaaagctgat aaaaaaagag   2700

gggaaggaga agatgaggtg gaagaagagt caacagcttt gcaaaaaact gacaaaaagg   2760

aaattttgaa aaaatcagag aaagatacaa attctaaagt aagcaaggta aaacccaaag   2820

gcaaagttcg atggactggt tctcggacac gtggcagatg gaaatattcc agcaatgatg   2880

aaagtgaagg gtctggcagt gaaaaatcat ctgcagcttc agaagaggag gaagaaaagg   2940

aaagtgaaga agccatccta gcagatgatg atgaaccatg caaaaaatgt ggccttccaa   3000

accatcctga gctaattctt ctgtgtgact cttgcgatag tggataccat actgcctgcc   3060

ttcgccctcc tctgatgatc atcccagatg gagaatggtt ctgcccacct tgccaacata   3120

aactgctctg tgaaaaatta gaggaacagt tgcaggattt ggatgttgcc ttaaagaaga   3180

aagagcgtgc cgaacgaaga aaagaacgct tggtgtatgt tggtatcagt attgaaaaca   3240

tcattcctcc acaagagcca gacttttctg aagatcaaga agaaaagaaa aaagattcaa   3300

aaaaatccaa agcaaacttg cttgaaagga ggtcaacaag aacaaggaaa tgtataagct   3360

acagatttga tgagtttgat gaagcaattg atgaagctat tgaagatgac atcaaagaag   3420

ccgatggagg aggagttggc cgaggaaaag atatctccac catcacaggt catcgtggga   3480

aagacatctc tactattttg gatgaagaaa gaaaagaaaa taaacgaccc cagagggcag   3540

ctgctgctcg aaggaagaaa cgccggcgat taaatgatct ggacagtgat agcaacctgg   3600

atgaagaaga gagcgaggat gaattcaaga tcagtgatgg atctcaagat gagtttgttg   3660

tgtctgatga aaacccagat gaaagtgaag aagatccgcc atctaatgat gacagtgaca   3720

ctgacttttg tagccgtaga ctgaggcgac acccctctcg gccaatgagg cagagcaggc   3780

gtttgcgaag aaagacccca aagaaaaaat attccgatga tgatgaagag gaggaatctg   3840

aggagaatag tagagactct gaaagtgact tcagtgatga ttttagtgat gattttgtag   3900

aaactcggcg aaggcggtca aggagaaatc agaaaagaca aattaactac aaagaagact   3960

cagaaagtga cggttcccag aagagtttgc gacgtggtaa agaaataagg cgagtacaca   4020

agcgaagact ttccagctca gagagtgaag agagctattt gtccaagaac tctgaagatg   4080

atgagctagc taaagaatca aagcggtcag ttcgaaagcg gggccgaagc acagacgagt   4140

attcagaagc agatgaggag gaggaggaag aggaaggcaa accatcccgc aaacggctac   4200

accggattga gacggatgag gaggagagtt gtgacaatgc tcatggagat gcaaatcagc   4260

ctgcccgtga cagccagcct agggtcctgc cctcagaaca agagagcacc aagaagccct   4320

accggataga aagtgatgag gaagaggact ttgaaaatgt aggcaaagtg gggagcccat   4380

tggactatag cttagtggac ttaccttcaa ccaatggaca gagccctggc aaagccattg   4440

agaacttgat tggcaagcct actgagaagt ctcagacccc caaggacaac agcacagcca   4500

gtgcaagcct agcctccaat gggacaagtg gtgggcagga ggcaggagca ccagaagagg   4560

aggaagatga gcttttgaga gtgactgacc ttgttgatta tgtctgtaac agtgaacagt   4620

tataagactt tttttccatt tttgtgctaa tttattccac ggtagctctc acaccagcgg   4680

gccagttatt aaaagctgtt taatttttcc tagaaaactc cactacagaa tgacttttag   4740

aagaaaaatt tcaacaaatc ctgaagtctt tctgtgaagt gaccagttct gaactttgaa   4800

gataaataat tgctgtaaat tccttttgat tttctttttc caggttcatg gtccttggta   4860

atttcattca tggaaaaaaa tcttattata ataacaacaa agatttgtat atttttgact   4920

ttatatttcc tgagctctcc tgactttgtg aaaaagggtg gatgaaaatg cattccgaat   4980

ctgtgagggc ccaaaacaga atttaggggt gggtgaaagc acttgtgctt tagctttttc   5040

atattaaata tatattatat ttaaacattc atggcataga tgatgattta cagacaattt   5100

aaaagttcaa gtctgtactg ttacagtttg agaattgtag ataacatcat acataagtca   5160

tttagtaaca gcctttgtga aatgaacttg tttactattg gagataacca cacttaataa   5220

agaagagaca gtgaaagtac catcataatt aacctaaatt tttgttatag cagagtttct   5280

tgtttaaaaa aaaataaaat catctgaaaa gcatttgtac agtaaaatgt ataatgaagc   5340

tttgccaacc agactgtgct agcaacaaat ttttttaaat aagctttatg cagtggtaat   5400

aaggtggcct caaatatatt gtgtctgatg gagagttatt agtgaaatga atgtggtctt   5460

tcttaaggcc tgggtggact gtaaactttg ccaatagtat aactcttgtc ttctggccac   5520

ttgatgttta aatatctgaa atatcatttt gaaaaaaata catctatata taacatacat   5580

gaagagatgc taagctgaca gtgatatttt agcacatttg aagactggga agagattttc   5640

aggtgaattt taactggtct attcttgccc ttagtatcta cttcaaattg aagtctacaa   5700

acaaagcagt tcctttggga ggtttttagt ttgagtttta gcgtgtgtgt gtgtttgtgt   5760

gtgtgcgtgt gcgtgtgtgt gtgtgttgga atttcctatc tgcctggata tattagcaga   5820

gtttgaatgt agttttggcc tttggccatt agacttctat taaaattcat taatagtcat   5880

acaaccaaca tagagttgaa tgagaactgc cgatgtaatt aataggcatg acatccattt   5940

caaacatctc aacactttaa agaaaagccc tttgtttcaa gaaaaaaggg tttgtaacta   6000

actaaatacc taacatgtaa ttgacactaa aatatgaact ttgtcttatt tagtttctgt   6060

tatagctgta aaatttcagg cagagccata acattgtaca gagtgtagca cttgtgatta   6120

aacctagcct gttaaatcct gaaaccttca accattactt ctgtgaatac tttagccctg   6180

ggatttgggt ttttctgttc cggtgttgtg tctgttgccg gcaatggaca caccatatct   6240

gctgctggcc caaggaacgt cattaatttt tctttccaaa ttaagtatta tgtgctagtc   6300

agtgtatagt aaagcacttc tcttttttat tactaaaaag ctggcattag atttgcatta   6360

taaatacctc tctaggaact ttatactcct tttccttctt caacaggtat tgcccttaaa   6420

tcttatcttt tggccttgaa agtttatagc tattgttttt cagttgttcg ttgttttgtt   6480

ttgtttcact ttagttctgt agtacctgcc cattaatatt tttgctttga ttctagcaat   6540

gtgtatgtat ctgtataaaa aataaaataa tgaaagcaac ctaaaaatag gatgcaccaa   6600

tagcatgtgg ttccaagtaa gttgtgattt ttattttgag acagtgttcc actggaaggg   6660

agggaagggc ttacattcac agacagtaaa gcagggctgt gtaaggagct acatttactt   6720

aacagtctcc tttccagcta ggtttgtttt atttatttgc aagtcagcta agaattaacc   6780

ttttaaacca tctaaaacag gcaagcaata taaagatttc tactagtgca aggtaagtgg   6840

tttgaatata caagtgccct ttcctgccac ccagtctcac taccgtttta gtcctgcagc   6900

tgggtaaagc cactattgtg tggaaactct cccatgtgcc ctgtctctac ctctggacac   6960

accagctcct tcttccacct attctattcc tcagttaagc caagtgatca gaagtagtat   7020

taaatgggta gataatttta acaggatgcc taatgtgaaa taaggagtta tttttactct   7080

tctactatag aaagcctaag gtaattctta ccatctcaaa gactgagtat tccatttagg   7140

tttggagacc acttgtgctg tgctgcctga tatttaccaa acttgaataa gtgttcgtca   7200

acttgatagt gaatgtaccc cttctcacct tatattttga ttaaatcaat taactatagg   7260

tcatctacca agaatgtaat ccaagcggtt gataaaacat tattaggcag atagattatt   7320

gattattaaa ttttgagcag tgcaaaaacg gttttgctgc ttggagttca gattcagtcc   7380

ctcaaagagt ttatgatcac tgaaatacac tctgaaggta ttctgaagaa gttaaaaaat   7440

tttagaaaac gaaatgttct gtatacaaag acaatacagt cactacgaac tgcagaaagt   7500

ataggaaagc agtaattgat gtagagttta gacagtcttg gatctttttt agagcactaa   7560

ccatggattt agactcaaaa tagctgctac ataatagagc cctttaataa tttaaacccc   7620

ccttgttgaa atacaagttg gactcccagt gtcaaactct agactgtagc taatgtatta   7680

aagggagatg tagattaata ttcagtatat ttagtttgca atttctgaaa aggtttgaaa   7740

actagtcagc ttttcacaca gcagaagctt tgaactgaaa tatgtgtgaa aaggacgcag   7800

actgaaaacg ttttggtttt gtacatcagt gctgatgaaa ttagtgtaaa acattttcca   7860

tcattggcac attactgcaa aatgatggca gagatatttt caagaatgta catcaagtta   7920

tatttccttg acatcctttt ttcaattggt caaggttaca gattcagagg ataaagggta   7980

gtttcattta gaataaattc atgtctactg gcaatctata tataaaagtg acctgcccaa   8040

gaaccaaaaa ctttaaatgc taatgaagct tttgaaaaat aatttttaaa caaattaatt   8100

ttaaaagggt gttacacgta cccagttttt actttttagt tgatgaaacc catcctataa   8160

tatacatttg agcaaagtac acatattaag aaaaacatgg acatttactt gtttaatagt   8220

caaaatgatg aggaaatgtt agctgttttt aagtgggact ggtggggtgt cctttgtcac   8280

aaggaatgct tttttagctt gtttgtgggc ataagagatg ttaacccttt gctgattcta   8340

ccacacaact gtaaagaacc taatgaatct acaagtttaa tattcagaaa aagctaggaa   8400

ctccgctctt taccagtaca gtggaacagg cccgttattc aaggtgatgc ctcacagcta   8460

tagaacaact attcaaagac ccagagttaa atggtacatg tgtatatgtg tgtgtgtgtg   8520

tgcacacgca cacacttcag ataagtatca                                    8550


<210>  7989
<211>  1441
<212>  PRT
<213>  Homo sapiens

<400>  7989

Met Ala Thr Ala Ala Ala Ala Ala Ala Val Met Ala Pro Pro Gly Cys 
1               5                   10                  15


Pro Gly Ser Cys Pro Asn Phe Ala Val Val Cys Ser Phe Leu Glu Arg 
            20                  25                  30


Tyr Gly Pro Leu Leu Asp Leu Pro Glu Leu Pro Phe Pro Glu Leu Glu 
        35                  40                  45


Arg Val Leu Gln Ala Pro Pro Pro Asp Val Gly Asn Gly Glu Val Pro 
    50                  55                  60


Lys Glu Leu Val Glu Leu His Leu Lys Leu Met Arg Lys Ile Gly Lys 
65                  70                  75                  80


Ser Val Thr Ala Asp Arg Trp Glu Lys Tyr Leu Ile Lys Ile Cys Gln 
                85                  90                  95


Glu Phe Asn Ser Thr Trp Ala Trp Glu Met Glu Lys Lys Gly Tyr Leu 
            100                 105                 110


Glu Met Ser Val Glu Cys Lys Leu Ala Leu Leu Lys Tyr Leu Cys Glu 
        115                 120                 125


Cys Gln Phe Asp Asp Asn Leu Lys Phe Lys Asn Ile Ile Asn Glu Glu 
    130                 135                 140


Asp Ala Asp Thr Met Arg Leu Gln Pro Ile Gly Arg Asp Lys Asp Gly 
145                 150                 155                 160


Leu Met Tyr Trp Tyr Gln Leu Asp Gln Asp His Asn Val Arg Met Tyr 
                165                 170                 175


Ile Glu Glu Gln Asp Asp Gln Asp Gly Ser Ser Trp Lys Cys Ile Val 
            180                 185                 190


Arg Asn Arg Asn Glu Leu Ala Glu Thr Leu Ala Leu Leu Lys Ala Gln 
        195                 200                 205


Ile Asp Pro Val Leu Leu Lys Asn Ser Ser Gln Gln Asp Asn Ser Ser 
    210                 215                 220


Arg Glu Ser Pro Ser Leu Glu Asp Glu Glu Thr Lys Lys Glu Glu Glu 
225                 230                 235                 240


Thr Pro Lys Gln Glu Glu Gln Lys Glu Ser Glu Lys Met Lys Ser Glu 
                245                 250                 255


Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala Asn Val Leu Glu 
            260                 265                 270


Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys Glu Leu Val Lys 
        275                 280                 285


Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro Glu Asn Glu Glu 
    290                 295                 300


Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys Glu Asn Val Lys 
305                 310                 315                 320


Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp Pro Lys Asp Thr 
                325                 330                 335


Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro Glu Arg Ile Glu 
            340                 345                 350


Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr Glu Lys Ser Thr 
        355                 360                 365


Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala Lys Ile Pro Leu 
    370                 375                 380


Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp Ser Pro Val Lys 
385                 390                 395                 400


Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu Phe Leu Lys Asp 
                405                 410                 415


Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile Ser Thr Ile Thr 
            420                 425                 430


Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly Glu Val Ser Asp 
        435                 440                 445


Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile Glu Thr Lys Phe 
    450                 455                 460


Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys Asp Arg Asn Ile 
465                 470                 475                 480


Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser Val Ile Thr Ser 
                485                 490                 495


Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro Leu Arg Lys Asp 
            500                 505                 510


Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser Gln Lys Ala Gln 
        515                 520                 525


Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser Leu Asp Ser Ser 
    530                 535                 540


Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu Ser Ser Thr Glu 
545                 550                 555                 560


Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys Thr Lys Lys Asp 
                565                 570                 575


Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu Glu Lys Ser Lys 
            580                 585                 590


Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser Pro Ile Pro Glu 
        595                 600                 605


Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro Gly Ser Pro Glu 
    610                 615                 620


Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp His Cys Glu Lys 
625                 630                 635                 640


Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser Thr Ser Thr Val 
                645                 650                 655


Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr Leu Lys Glu Asp 
            660                 665                 670


Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp Asn Ala Gln Thr 
        675                 680                 685


Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser Met Gln Lys Ser 
    690                 695                 700


Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr Thr Ala Ser Glu 
705                 710                 715                 720


Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly Ile Lys Leu Thr 
                725                 730                 735


Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser Pro Pro Lys Val 
            740                 745                 750


Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys Glu Glu Glu Lys 
        755                 760                 765


Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg Ile Ser Arg Pro 
    770                 775                 780


Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala Asp Lys Lys Arg 
785                 790                 795                 800


Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr Ala Leu Gln Lys 
                805                 810                 815


Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys Asp Thr Asn Ser 
            820                 825                 830


Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg Trp Thr Gly Ser 
        835                 840                 845


Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp Glu Ser Glu Gly 
    850                 855                 860


Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu Glu Glu Glu Lys 
865                 870                 875                 880


Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu Pro Cys Lys Lys 
                885                 890                 895


Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu Cys Asp Ser Cys 
            900                 905                 910


Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro Leu Met Ile Ile 
        915                 920                 925


Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His Lys Leu Leu Cys 
    930                 935                 940


Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val Ala Leu Lys Lys 
945                 950                 955                 960


Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val Tyr Val Gly Ile 
                965                 970                 975


Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp Phe Ser Glu Asp 
            980                 985                 990


Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys Ala Asn Leu Leu 
        995                 1000                1005


Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser Tyr Arg Phe Asp 
    1010                1015                1020


Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp Asp Ile Lys Glu 
1025                1030                1035                1040


Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile Ser Thr Ile Thr 
                1045                1050                1055


Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp Glu Glu Arg Lys 
            1060                1065                1070


Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg Arg Lys Lys Arg 
        1075                1080                1085


Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu Asp Glu Glu Glu 
    1090                1095                1100


Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln Asp Glu Phe Val 
1105                1110                1115                1120


Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp Pro Pro Ser Asn 
                1125                1130                1135


Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu Arg Arg His Pro 
            1140                1145                1150


Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg Lys Thr Pro Lys 
        1155                1160                1165


Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser Glu Glu Asn Ser 
    1170                1175                1180


Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser Asp Asp Phe Val 
1185                1190                1195                1200


Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys Arg Gln Ile Asn 
                1205                1210                1215


Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys Ser Leu Arg Arg 
            1220                1225                1230


Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu Ser Ser Ser Glu 
        1235                1240                1245


Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp Asp Glu Leu Ala 
    1250                1255                1260


Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg Ser Thr Asp Glu 
1265                1270                1275                1280


Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu Gly Lys Pro Ser 
                1285                1290                1295


Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu Glu Ser Cys Asp 
            1300                1305                1310


Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp Ser Gln Pro Arg 
        1315                1320                1325


Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro Tyr Arg Ile Glu 
    1330                1335                1340


Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys Val Gly Ser Pro 
1345                1350                1355                1360


Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn Gly Gln Ser Pro 
                1365                1370                1375


Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr Glu Lys Ser Gln 
            1380                1385                1390


Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu Ala Ser Asn Gly 
        1395                1400                1405


Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu Glu Glu Asp Glu 
    1410                1415                1420


Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys Asn Ser Glu Gln 
1425                1430                1435                1440


Leu 



<210>  7990
<211>  6607
<212>  DNA
<213>  Homo sapiens

<400>  7990
ctggtttatc aacttgacga gaatcatttc aaaattttag gaaaaaaatt tatgtctcag     60

taaaactttg tttagaatta ggtttttcag tagcaaggat aaggtgaagg gattaaaaat    120

gtacgtaaaa ttagtagtca atgaattctg gaatgcagtc tgtataatcc tattcagaga    180

ttatgctatt tactgaatat agctttggtt gtgtttaaat ctgcactagt attaggtgct    240

ccttaaaagt tgaaaatata tagccaataa ggtataaaga agaattgaca gataaatcta    300

aacagtttct ttgtatagta ctaacttctg aaatgttcag tggtggcatt tgataaagta    360

agttgtaata tgatcacatt gaggaatgtt atataattat taaactcaat ttttataaaa    420

ggcatcattt tataaaagta tcataagaaa gtgccaatgt ttcaatgaat aaattgaggc    480

aacatgatac caacttagtg aaaaatatac aagaccagaa ggaagtaacc taaaatatta    540

ctagtgattg cctctgggta ataggatatg ggctttttgt ctttctatat ttttcatttt    600

cccactgccg tgttcctggt acctcagtga aatgaagtgc tcagttcttt taacagttgt    660

cagtttttaa aacaaatata gtcttctgga aatgttttag gtagcatttt caattttatg    720

tttttaagcc atctcttgaa tttgaataaa ttatttgaac tgcataaata tttgcaatcc    780

attgagaaca ccaaaacaaa aagtaaaaag cagaaaccta aatttttcta aatttttttt    840

aatatctaga agttgtatct caaagttttt gtaattttct tcattgtcag attttatttt    900

ttactgtcaa atatccaatg acagaggcca cctcttttaa aatagaaact ttaaatggaa    960

atatacatta tactaagtct tatattttat agccttgaaa gtttctattc atgtaattaa   1020

gctttttctg atttttagag gaacagaaag aaagtgaaaa gatgaaaagt gaggagcagc   1080

ctatggattt agaaaaccgt tctacagcca atgttctaga agagactact gtgaaaaaag   1140

aaaaagaaga tgaaaaggaa cttgtgaaac tgccagtcat agtgaagcta gaaaaacctt   1200

tgccagaaaa tgaagaaaaa aagattatca aagaagaaag tgattccttc aaggaaaatg   1260

tcaaacccat taaagttgag gtgaaggaat gtagagcaga tcctaaagat accaaaagta   1320

gcatggagaa gccagtggca caggagcctg aaaggatcga atttggtggc aatattaaat   1380

cttctcacga aattactgag aaatctactg aagaaactga gaaacttaaa aatgaccagc   1440

aggccaagat accactaaaa aaacgagaaa ttaaactgag tgatgatttt gacagtccag   1500

tcaagggacc tttgtgtaaa tcagttactc caacaaaaga gtttttgaaa gatgaaataa   1560

aacaagagga agagacttgt aaaaggatct ctacaatcac tgctttgggt catgaaggga   1620

aacagctggt aaatggagaa gttagtgatg aaagggtagc tccaaatttt aagacagaac   1680

caatagagac aaagttttat gagacaaagg aagagagcta tagcccctct aaggacagaa   1740

atatcatcac ggagggaaat ggaacagagt ccttaaattc tgtcataaca agtatgaaaa   1800

caggtgagct tgagaaagaa acagcccctt tgaggaaaga tgcagatagt tcaatatcag   1860

tcttagagat ccatagtcaa aaagcacaaa tagaggaacc cgatcctcca gaaatggaaa   1920

cttctcttga ttcttctgag atggcaaaag atctctcttc aaaaactgct ttatcttcca   1980

ccgagtcgtg taccatgaaa ggtgaagaga agtctcccaa aactaagaag gataagcgcc   2040

caccaatcct agaatgtctt gaaaagttag agaagtccaa aaagactttt cttgataagg   2100

acgcacaaag attgagtcca ataccagaag aagttccaaa gagtactcta gagtcagaaa   2160

agcctggctc tcctgaggca gctgaaactt ctccaccatc taatatcatt gaccactgtg   2220

agaaactagc ctcagaaaaa gaagtggtag aatgccagag tacaagtact gttggtggcc   2280

agtctgtgaa aaaagtagac ctagaaaccc taaaagagga ttctgagttc acaaaggtag   2340

aaatggataa tctggacaat gcccagacct ctggcataga ggagccttct gagacaaagg   2400

gttctatgca aaaaagcaaa ttcaaatata agttggttcc tgaagaagaa accactgcct   2460

cagaaaatac agagataacc tctgaaaggc agaaagaggg catcaaatta acaatcagga   2520

tatcaagtcg gaaaaagaag cccgattctc cccccaaagt tctagaacca gaaaacaagc   2580

aagagaagac agaaaaggaa gaggagaaaa caaatgtggg tcgtacttta agaagatctc   2640

caagaatatc tagacccact gcaaaagtgg ctgagatcag agatcagaaa gctgataaaa   2700

aaagagggga aggagaagat gaggtggaag aagagtcaac agctttgcaa aaaactgaca   2760

aaaaggaaat tttgaaaaaa tcagagaaag atacaaattc taaagtaagc aaggtaaaac   2820

ccaaaggcaa agttcgatgg actggttctc ggacacgtgg cagatggaaa tattccagca   2880

atgatgaaag tgaagggtct ggcagtgaaa aatcatctgc agcttcagaa gaggaggaag   2940

aaaaggaaag tgaagaagcc atcctagcag atgatgatga accatgcaaa aaatgtggcc   3000

ttccaaacca tcctgagcta attcttctgt gtgactcttg cgatagtgga taccatactg   3060

cctgccttcg ccctcctctg atgatcatcc cagatggaga atggttctgc ccaccttgcc   3120

aacataaact gctctgtgaa aaattagagg aacagttgca ggatttggat gttgccttaa   3180

agaagaaaga gcgtgccgaa cgaagaaaag aacgcttggt gtatgttggt atcagtattg   3240

aaaacatcat tcctccacaa gagccagact tttctgaaga tcaagaagaa aagaaaaaag   3300

attcaaaaaa atccaaagca aacttgcttg aaaggaggtc aacaagaaca aggaaatgta   3360

taagctacag atttgatgag tttgatgaag caattgatga agctattgaa gatgacatca   3420

aagaagccga tggaggagga gttggccgag gaaaagatat ctccaccatc acaggtcatc   3480

gtgggaaaga catctctact attttggatg aagaaagaaa agaaaataaa cgaccccaga   3540

gggcagctgc tgctcgaagg aagaaacgcc ggcgattaaa tgatctggac agtgatagca   3600

acctggatga agaagagagc gaggatgaat tcaagatcag tgatggatct caagatgagt   3660

ttgttgtgtc tgatgaaaac ccagatgaaa gtgaagaaga tccgccatct aatgatgaca   3720

gtgacactga cttttgtagc cgtagactga ggcgacaccc ctctcggcca atgaggcaga   3780

gcaggcgttt gcgaagaaag accccaaaga aaaaatattc cgatgatgat gaagaggagg   3840

aatctgagga gaatagtaga gactctgaaa gtgacttcag tgatgatttt agtgatgatt   3900

ttgtagaaac tcggcgaagg cggtcaagga gaaatcagaa aagacaaatt aactacaaag   3960

aagactcaga aagtgacggt tcccagaaga gtttgcgacg tggtaaagaa ataaggcgag   4020

tacacaagcg aagactttcc agctcagaga gtgaagagag ctatttgtcc aagaactctg   4080

aagatgatga gctagctaaa gaatcaaagc ggtcagttcg aaagcggggc cgaagcacag   4140

acgagtattc agaagcagat gaggaggagg aggaagagga aggcaaacca tcccgcaaac   4200

ggctacaccg gattgagacg gatgaggagg agagttgtga caatgctcat ggagatgcaa   4260

atcagcctgc ccgtgacagc cagcctaggg tcctgccctc agaacaagag agcaccaaga   4320

agccctaccg gatagaaagt gatgaggaag aggactttga aaatgtaggc aaagtgggga   4380

gcccattgga ctatagctta gtggacttac cttcaaccaa tggacagagc cctggcaaag   4440

ccattgagaa cttgattggc aagcctactg agaagtctca gacccccaag gacaacagca   4500

cagccagtgc aagcctagcc tccaatggga caagtggtgg gcaggaggca ggagcaccag   4560

aagaggagga agatgagctt ttgagagtga ctgaccttgt tgattatgtc tgtaacagtg   4620

aacagttata agactttttt tccatttttg tgctaattta ttccacggta gctctcacac   4680

cagcgggcca gttattaaaa gctgtttaat ttttcctaga aaactccact acagaatgac   4740

ttttagaaga aaaatttcaa caaatcctga agtctttctg tgaagtgacc agttctgaac   4800

tttgaagata aataattgct gtaaattcct tttgattttc tttttccagg ttcatggtcc   4860

ttggtaattt cattcatgga aaaaaatctt attataataa caacaaagat ttgtatattt   4920

ttgactttat atttcctgag ctctcctgac tttgtgaaaa agggtggatg aaaatgcatt   4980

ccgaatctgt gagggcccaa aacagaattt aggggtgggt gaaagcactt gtgctttagc   5040

tttttcatat taaatatata ttatatttaa acattcatgg catagatgat gatttacaga   5100

caatttaaaa gttcaagtct gtactgttac agtttgagaa ttgtagataa catcatacat   5160

aagtcattta gtaacagcct ttgtgaaatg aacttgttta ctattggaga taaccacact   5220

taataaagaa gagacagtga aagtaccatc ataattaacc taaatttttg ttatagcaga   5280

gtttcttgtt taaaaaaaaa taaaatcatc tgaaaagcat ttgtacagta aaatgtataa   5340

tgaagctttg ccaaccagac tgtgctagca acaaattttt ttaaataagc tttatgcagt   5400

ggtaataagg tggcctcaaa tatattgtgt ctgatggaga gttattagtg aaatgaatgt   5460

ggtctttctt aaggcctggg tggactgtaa actttgccaa tagtataact cttgtcttct   5520

ggccacttga tgtttaaata tctgaaatat cattttgaaa aaaatacatc tatatataac   5580

atacatgaag agatgctaag ctgacagtga tattttagca catttgaaga ctgggaagag   5640

attttcaggt gaattttaac tggtctattc ttgcccttag tatctacttc aaattgaagt   5700

ctacaaacaa agcagttcct ttgggaggtt tttagtttga gttttagcgt gtgtgtgtgt   5760

ttgtgtgtgt gcgtgtgcgt gtgtgtgtgt gttggaattt cctatctgcc tggatatatt   5820

agcagagttt gaatgtagtt ttggcctttg gccattagac ttctattaaa attcattaat   5880

agtcatacaa ccaacataga gttgaatgag aactgccgat gtaattaata ggcatgacat   5940

ccatttcaaa catctcaaca ctttaaagaa aagccctttg tttcaagaaa aaagggtttg   6000

taactaacta aatacctaac atgtaattga cactaaaata tgaactttgt cttatttagt   6060

ttctgttata gctgtaaaat ttcaggcaga gccataacat tgtacagagt gtagcacttg   6120

tgattaaacc tagcctgtta aatcctgaaa ccttcaacca ttacttctgt gaatacttta   6180

gccctgggat ttgggttttt ctgttccggt gttgtgtctg ttgccggcaa tggacacacc   6240

atatctgctg ctggcccaag gaacgtcatt aatttttctt tccaaattaa gtattatgtg   6300

ctagtcagtg tatagtaaag cacttctctt ttttattact aaaaagctgg cattagattt   6360

gcattataaa tacctctcta ggaactttat actccttttc cttcttcaac aggtattgcc   6420

cttaaatctt atcttttggc cttgaaagtt tatagctatt gtttttcagt tgttcgttgt   6480

tttgttttgt ttcactttag ttctgtagta cctgcccatt aatatttttg ctttgattct   6540

agcaatgtgt atgtatctgt ataaaaaata aaataatgaa agcaacctaa aaataggatg   6600

caccaat                                                             6607


<210>  7991
<211>  1189
<212>  PRT
<213>  Homo sapiens

<400>  7991

Met Lys Ser Glu Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala 
1               5                   10                  15


Asn Val Leu Glu Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys 
            20                  25                  30


Glu Leu Val Lys Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro 
        35                  40                  45


Glu Asn Glu Glu Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys 
    50                  55                  60


Glu Asn Val Lys Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp 
65                  70                  75                  80


Pro Lys Asp Thr Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro 
                85                  90                  95


Glu Arg Ile Glu Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr 
            100                 105                 110


Glu Lys Ser Thr Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala 
        115                 120                 125


Lys Ile Pro Leu Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp 
    130                 135                 140


Ser Pro Val Lys Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu 
145                 150                 155                 160


Phe Leu Lys Asp Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile 
                165                 170                 175


Ser Thr Ile Thr Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly 
            180                 185                 190


Glu Val Ser Asp Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile 
        195                 200                 205


Glu Thr Lys Phe Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys 
    210                 215                 220


Asp Arg Asn Ile Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser 
225                 230                 235                 240


Val Ile Thr Ser Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro 
                245                 250                 255


Leu Arg Lys Asp Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser 
            260                 265                 270


Gln Lys Ala Gln Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser 
        275                 280                 285


Leu Asp Ser Ser Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu 
    290                 295                 300


Ser Ser Thr Glu Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys 
305                 310                 315                 320


Thr Lys Lys Asp Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu 
                325                 330                 335


Glu Lys Ser Lys Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser 
            340                 345                 350


Pro Ile Pro Glu Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro 
        355                 360                 365


Gly Ser Pro Glu Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp 
    370                 375                 380


His Cys Glu Lys Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser 
385                 390                 395                 400


Thr Ser Thr Val Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr 
                405                 410                 415


Leu Lys Glu Asp Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp 
            420                 425                 430


Asn Ala Gln Thr Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser 
        435                 440                 445


Met Gln Lys Ser Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr 
    450                 455                 460


Thr Ala Ser Glu Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly 
465                 470                 475                 480


Ile Lys Leu Thr Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser 
                485                 490                 495


Pro Pro Lys Val Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys 
            500                 505                 510


Glu Glu Glu Lys Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg 
        515                 520                 525


Ile Ser Arg Pro Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala 
    530                 535                 540


Asp Lys Lys Arg Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr 
545                 550                 555                 560


Ala Leu Gln Lys Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys 
                565                 570                 575


Asp Thr Asn Ser Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg 
            580                 585                 590


Trp Thr Gly Ser Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp 
        595                 600                 605


Glu Ser Glu Gly Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu 
    610                 615                 620


Glu Glu Glu Lys Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu 
625                 630                 635                 640


Pro Cys Lys Lys Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu 
                645                 650                 655


Cys Asp Ser Cys Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro 
            660                 665                 670


Leu Met Ile Ile Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His 
        675                 680                 685


Lys Leu Leu Cys Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val 
    690                 695                 700


Ala Leu Lys Lys Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val 
705                 710                 715                 720


Tyr Val Gly Ile Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp 
                725                 730                 735


Phe Ser Glu Asp Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys 
            740                 745                 750


Ala Asn Leu Leu Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser 
        755                 760                 765


Tyr Arg Phe Asp Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp 
    770                 775                 780


Asp Ile Lys Glu Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile 
785                 790                 795                 800


Ser Thr Ile Thr Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp 
                805                 810                 815


Glu Glu Arg Lys Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg 
            820                 825                 830


Arg Lys Lys Arg Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu 
        835                 840                 845


Asp Glu Glu Glu Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln 
    850                 855                 860


Asp Glu Phe Val Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp 
865                 870                 875                 880


Pro Pro Ser Asn Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu 
                885                 890                 895


Arg Arg His Pro Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg 
            900                 905                 910


Lys Thr Pro Lys Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser 
        915                 920                 925


Glu Glu Asn Ser Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser 
    930                 935                 940


Asp Asp Phe Val Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys 
945                 950                 955                 960


Arg Gln Ile Asn Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys 
                965                 970                 975


Ser Leu Arg Arg Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu 
            980                 985                 990


Ser Ser Ser Glu Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp 
        995                 1000                1005


Asp Glu Leu Ala Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg 
    1010                1015                1020


Ser Thr Asp Glu Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu 
1025                1030                1035                1040


Gly Lys Pro Ser Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu 
                1045                1050                1055


Glu Ser Cys Asp Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp 
            1060                1065                1070


Ser Gln Pro Arg Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro 
        1075                1080                1085


Tyr Arg Ile Glu Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys 
    1090                1095                1100


Val Gly Ser Pro Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn 
1105                1110                1115                1120


Gly Gln Ser Pro Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr 
                1125                1130                1135


Glu Lys Ser Gln Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu 
            1140                1145                1150


Ala Ser Asn Gly Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu 
        1155                1160                1165


Glu Glu Asp Glu Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys 
    1170                1175                1180


Asn Ser Glu Gln Leu 
1185


<210>  7992
<211>  6601
<212>  DNA
<213>  Homo sapiens

<400>  7992
tttcattccc cctgtcacac gaggcagtgg caagcccgaa ggggaggaga gaagggggcg     60

gaaagagggc ggaaagtgaa aggcgccgag ggccgctctg tctcccgtct gactcggttc    120

tcgactgctc cgggccgccg atgtattgtg ggatcgcgga gccgtccctg agacgctggg    180

atccgcagag gagcccactt gagagcgcct cctgtcgtct gtaaggttgc cttgccatcc    240

ctcggcacca caacttcccc cgccccccca tcgcctcctc ctccatcctc cagttcaaaa    300

tggcgacggc ggcggcagcg gcggcggtga tggctcctcc gggctgcccg ggttcgtgcc    360

ccaacttcgc cgtagtctgc tccttcttgg agcgctacgg gccgctgcta gacctgcctg    420

agttgccgtt ccctgagctg gagcgggtgc tgcaggcgcc gccgccggac gtcggcaacg    480

gagaagtacc aaaagaattg gtggagctcc atttgaagct gatgaggaaa attggcaaat    540

ctgttactgc agacagatgg gaaaaatatt tgatcaagat atgccaagag tttaacagta    600

cctgggcatg ggagatggag aagaagggct atcttgaaat gagtgttgaa tgcaaactag    660

cactcttaaa gtacctctgt gagtgtcagt ttgatgacaa tctcaaattc aagaatatta    720

ttaatgagga ggatgccgat actatgcgtc tccagccaat tggtcgagac aaagatggcc    780

tcatgtactg gtaccaattg gatcaagatc acaatgtcag aatgtacata gaagaacaag    840

atgatcaaga tggctcttca tggaaatgca ttgtcagaaa tcgaaacgag ttggctgaga    900

ctcttgcact cctgaaagca caaattgatc ctgtactatt gaaaaactct agccaacaag    960

acaactcttc tcgggaaagt cccagcttag aggatgagga gactaaaaaa gaggaagaaa   1020

cacctaaaca agaggaacag aaagaaagtg aaaagatgaa aagtgaggag cagcctatgg   1080

atttagaaaa ccgttctaca gccaatgttc tagaagagac tactgtgaaa aaagaaaaag   1140

aagatgaaaa ggaacttgtg aaactgccag tcatagtgaa gctagaaaaa cctttgccag   1200

aaaatgaaga aaaaaagatt atcaaagaag aaagtgattc cttcaaggaa aatgtcaaac   1260

ccattaaagt tgaggtgaag gaatgtagag cagatcctaa agataccaaa agtagcatgg   1320

agaagccagt ggcacaggag cctgaaagga tcgaatttgg tggcaatatt aaatcttctc   1380

acgaaattac tgagaaatct actgaagaaa ctgagaaact taaaaatgac cagcaggcca   1440

agataccact aaaaaaacga gaaattaaac tgagtgatga ttttgacagt ccagtcaagg   1500

gacctttgtg taaatcagtt actccaacaa aagagttttt gaaagatgaa ataaaacaag   1560

aggaagagac ttgtaaaagg atctctacaa tcactgcttt gggtcatgaa gggaaacagc   1620

tggtaaatgg agaagttagt gatgaaaggg tagctccaaa ttttaagaca gaaccaatag   1680

agacaaagtt ttatgagaca aaggaagaga gctatagccc ctctaaggac agaaatatca   1740

tcacggaggg aaatggaaca gagtccttaa attctgtcat aacaagtatg aaaacaggtg   1800

agcttgagaa agaaacagcc cctttgagga aagatgcaga tagttcaata tcagtcttag   1860

agatccatag tcaaaaagca caaatagagg aacccgatcc tccagaaatg gaaacttctc   1920

ttgattcttc tgagatggca aaagatctct cttcaaaaac tgctttatct tccaccgagt   1980

cgtgtaccat gaaaggtgaa gagaagtctc ccaaaactaa gaaggataag cgcccaccaa   2040

tcctagaatg tcttgaaaag ttagagaagt ccaaaaagac ttttcttgat aaggacgcac   2100

aaagattgag tccaatacca gaagaagttc caaagagtac tctagagtca gaaaagcctg   2160

gctctcctga ggcagctgaa acttctccac catctaatat cattgaccac tgtgagaaac   2220

tagcctcaga aaaagaagtg gtagaatgcc agagtacaag tactgttggt ggccagtctg   2280

tgaaaaaagt agacctagaa accctaaaag aggattctga gttcacaaag gtagaaatgg   2340

ataatctgga caatgcccag acctctggca tagaggagcc ttctgagaca aagggttcta   2400

tgcaaaaaag caaattcaaa tataagttgg ttcctgaaga agaaaccact gcctcagaaa   2460

atacagagat aacctctgaa aggcagaaag agggcatcaa attaacaatc aggatatcaa   2520

gtcggaaaaa gaagcccgat tctcccccca aagttctaga accagaaaac aagcaagaga   2580

agacagaaaa ggaagaggag aaaacaaatg tgggtcgtac tttaagaaga tctccaagaa   2640

tatctagacc cactgcaaaa gtggctgaga tcagagatca gaaagctgat aaaaaaagag   2700

gggaaggaga agatgaggtg gaagaagagt caacagcttt gcaaaaaact gacaaaaagg   2760

aaattttgaa aaaatcagag aaagatacaa attctaaagt aagcaaggta aaacccaaag   2820

gcaaagttcg atggactggt tctcggacac gtggcagatg gaaatattcc agcaatgatg   2880

aaagtgaagg gtctggcagt gaaaaatcat ctgcagcttc agaagaggag gaagaaaagg   2940

aaagtgaaga agccatccta gcagatgatg atgaaccatg caaaaaatgt ggccttccaa   3000

accatcctga gctaattctt ctgtgtgact cttgcgatag tggataccat actgcctgcc   3060

ttcgccctcc tctgatgatc atcccagatg gagaatggtt ctgcccacct tgccaacata   3120

aactgctctg tgaaaaatta gaggaacagt tgcaggattt ggatgttgcc ttaaagaaga   3180

aagagcgtgc cgaacgaaga aaagaacgct tggtgtatgt tggtatcagt attgaaaaca   3240

tcattcctcc acaagagcca gacttttctg aagatcaaga agaaaagaaa aaagattcaa   3300

aaaaatccaa agcaaacttg cttgaaagga ggtcaacaag aacaaggaaa tgtataagct   3360

acagatttga tgagtttgat gaagcaattg atgaagctat tgaagatgac atcaaagaag   3420

ccgatggagg aggagttggc cgaggaaaag atatctccac catcacaggt catcgtggga   3480

aagacatctc tactattttg gatgaagaaa gaaaagaaaa taaacgaccc cagagggcag   3540

ctgctgctcg aaggaagaaa cgccggcgat taaatgatct ggacagtgat agcaacctgg   3600

atgaagaaga gagcgaggat gaattcaaga tcagtgatgg atctcaagat gagtttgttg   3660

tgtctgatga aaacccagat gaaagtgaag aagatccgcc atctaatgat gacagtgaca   3720

ctgacttttg tagccgtaga ctgaggcgac acccctctcg gccaatgagg cagagcaggc   3780

gtttgcgaag aaagacccca aagaaaaaat attccgatga tgatgaagag gaggaatctg   3840

aggagaatag tagagactct gaaagtgact tcagtgatga ttttagtgat gattttgtag   3900

aaactcggcg aaggcggtca aggagaaatc agaaaagaca aattaactac aaagaagact   3960

cagaaagtga cggttcccag aagagtttgc gacgtggtaa agaaataagg cgagtacaca   4020

agcgaagact ttccagctca gagagtgaag agagctattt gtccaagaac tctgaagatg   4080

atgagctagc taaagaatca aagcggtcag ttcgaaagcg gggccgaagc acagacgagt   4140

attcagaagc agatgaggag gaggaggaag aggaaggcaa accatcccgc aaacggctac   4200

accggattga gacggatgag gaggagagtt gtgacaatgc tcatggagat gcaaatcagc   4260

ctgcccgtga cagccagcct agggtcctgc cctcagaaca agagagcacc aagaagccct   4320

accggataga aagtgatgag gaagaggact ttgaaaatgt aggcaaagtg gggagcccat   4380

tggactatag cttagtggac ttaccttcaa ccaatggaca gagccctggc aaagccattg   4440

agaacttgat tggcaagcct actgagaagt ctcagacccc caaggacaac agcacagcca   4500

gtgcaagcct agcctccaat gggacaagtg gtgggcagga ggcaggagca ccagaagagg   4560

aggaagatga gcttttgaga gtgactgacc ttgttgatta tgtctgtaac agtgaacagt   4620

tataagactt tttttccatt tttgtgctaa tttattccac ggtagctctc acaccagcgg   4680

gccagttatt aaaagctgtt taatttttcc tagaaaactc cactacagaa tgacttttag   4740

aagaaaaatt tcaacaaatc ctgaagtctt tctgtgaagt gaccagttct gaactttgaa   4800

gataaataat tgctgtaaat tccttttgat tttctttttc caggttcatg gtccttggta   4860

atttcattca tggaaaaaaa tcttattata ataacaacaa agatttgtat atttttgact   4920

ttatatttcc tgagctctcc tgactttgtg aaaaagggtg gatgaaaatg cattccgaat   4980

ctgtgagggc ccaaaacaga atttaggggt gggtgaaagc acttgtgctt tagctttttc   5040

atattaaata tatattatat ttaaacattc atggcataga tgatgattta cagacaattt   5100

aaaagttcaa gtctgtactg ttacagtttg agaattgtag ataacatcat acataagtca   5160

tttagtaaca gcctttgtga aatgaacttg tttactattg gagataacca cacttaataa   5220

agaagagaca gtgaaagtac catcataatt aacctaaatt tttgttatag cagagtttct   5280

tgtttaaaaa aaaataaaat catctgaaaa gcatttgtac agtaaaatgt ataatgaagc   5340

tttgccaacc agactgtgct agcaacaaat ttttttaaat aagctttatg cagtggtaat   5400

aaggtggcct caaatatatt gtgtctgatg gagagttatt agtgaaatga atgtggtctt   5460

tcttaaggcc tgggtggact gtaaactttg ccaatagtat aactcttgtc ttctggccac   5520

ttgatgttta aatatctgaa atatcatttt gaaaaaaata catctatata taacatacat   5580

gaagagatgc taagctgaca gtgatatttt agcacatttg aagactggga agagattttc   5640

aggtgaattt taactggtct attcttgccc ttagtatcta cttcaaattg aagtctacaa   5700

acaaagcagt tcctttggga ggtttttagt ttgagtttta gcgtgtgtgt gtgtttgtgt   5760

gtgtgcgtgt gcgtgtgtgt gtgtgttgga atttcctatc tgcctggata tattagcaga   5820

gtttgaatgt agttttggcc tttggccatt agacttctat taaaattcat taatagtcat   5880

acaaccaaca tagagttgaa tgagaactgc cgatgtaatt aataggcatg acatccattt   5940

caaacatctc aacactttaa agaaaagccc tttgtttcaa gaaaaaaggg tttgtaacta   6000

actaaatacc taacatgtaa ttgacactaa aatatgaact ttgtcttatt tagtttctgt   6060

tatagctgta aaatttcagg cagagccata acattgtaca gagtgtagca cttgtgatta   6120

aacctagcct gttaaatcct gaaaccttca accattactt ctgtgaatac tttagccctg   6180

ggatttgggt ttttctgttc cggtgttgtg tctgttgccg gcaatggaca caccatatct   6240

gctgctggcc caaggaacgt cattaatttt tctttccaaa ttaagtatta tgtgctagtc   6300

agtgtatagt aaagcacttc tcttttttat tactaaaaag ctggcattag atttgcatta   6360

taaatacctc tctaggaact ttatactcct tttccttctt caacaggtat tgcccttaaa   6420

tcttatcttt tggccttgaa agtttatagc tattgttttt cagttgttcg ttgttttgtt   6480

ttgtttcact ttagttctgt agtacctgcc cattaatatt tttgctttga ttctagcaat   6540

gtgtatgtat ctgtataaaa aataaaataa tgaaagcaac ctaaaaatag gatgcaccaa   6600

t                                                                   6601


<210>  7993
<211>  1441
<212>  PRT
<213>  Homo sapiens

<400>  7993

Met Ala Thr Ala Ala Ala Ala Ala Ala Val Met Ala Pro Pro Gly Cys 
1               5                   10                  15


Pro Gly Ser Cys Pro Asn Phe Ala Val Val Cys Ser Phe Leu Glu Arg 
            20                  25                  30


Tyr Gly Pro Leu Leu Asp Leu Pro Glu Leu Pro Phe Pro Glu Leu Glu 
        35                  40                  45


Arg Val Leu Gln Ala Pro Pro Pro Asp Val Gly Asn Gly Glu Val Pro 
    50                  55                  60


Lys Glu Leu Val Glu Leu His Leu Lys Leu Met Arg Lys Ile Gly Lys 
65                  70                  75                  80


Ser Val Thr Ala Asp Arg Trp Glu Lys Tyr Leu Ile Lys Ile Cys Gln 
                85                  90                  95


Glu Phe Asn Ser Thr Trp Ala Trp Glu Met Glu Lys Lys Gly Tyr Leu 
            100                 105                 110


Glu Met Ser Val Glu Cys Lys Leu Ala Leu Leu Lys Tyr Leu Cys Glu 
        115                 120                 125


Cys Gln Phe Asp Asp Asn Leu Lys Phe Lys Asn Ile Ile Asn Glu Glu 
    130                 135                 140


Asp Ala Asp Thr Met Arg Leu Gln Pro Ile Gly Arg Asp Lys Asp Gly 
145                 150                 155                 160


Leu Met Tyr Trp Tyr Gln Leu Asp Gln Asp His Asn Val Arg Met Tyr 
                165                 170                 175


Ile Glu Glu Gln Asp Asp Gln Asp Gly Ser Ser Trp Lys Cys Ile Val 
            180                 185                 190


Arg Asn Arg Asn Glu Leu Ala Glu Thr Leu Ala Leu Leu Lys Ala Gln 
        195                 200                 205


Ile Asp Pro Val Leu Leu Lys Asn Ser Ser Gln Gln Asp Asn Ser Ser 
    210                 215                 220


Arg Glu Ser Pro Ser Leu Glu Asp Glu Glu Thr Lys Lys Glu Glu Glu 
225                 230                 235                 240


Thr Pro Lys Gln Glu Glu Gln Lys Glu Ser Glu Lys Met Lys Ser Glu 
                245                 250                 255


Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala Asn Val Leu Glu 
            260                 265                 270


Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys Glu Leu Val Lys 
        275                 280                 285


Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro Glu Asn Glu Glu 
    290                 295                 300


Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys Glu Asn Val Lys 
305                 310                 315                 320


Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp Pro Lys Asp Thr 
                325                 330                 335


Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro Glu Arg Ile Glu 
            340                 345                 350


Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr Glu Lys Ser Thr 
        355                 360                 365


Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala Lys Ile Pro Leu 
    370                 375                 380


Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp Ser Pro Val Lys 
385                 390                 395                 400


Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu Phe Leu Lys Asp 
                405                 410                 415


Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile Ser Thr Ile Thr 
            420                 425                 430


Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly Glu Val Ser Asp 
        435                 440                 445


Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile Glu Thr Lys Phe 
    450                 455                 460


Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys Asp Arg Asn Ile 
465                 470                 475                 480


Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser Val Ile Thr Ser 
                485                 490                 495


Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro Leu Arg Lys Asp 
            500                 505                 510


Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser Gln Lys Ala Gln 
        515                 520                 525


Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser Leu Asp Ser Ser 
    530                 535                 540


Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu Ser Ser Thr Glu 
545                 550                 555                 560


Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys Thr Lys Lys Asp 
                565                 570                 575


Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu Glu Lys Ser Lys 
            580                 585                 590


Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser Pro Ile Pro Glu 
        595                 600                 605


Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro Gly Ser Pro Glu 
    610                 615                 620


Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp His Cys Glu Lys 
625                 630                 635                 640


Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser Thr Ser Thr Val 
                645                 650                 655


Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr Leu Lys Glu Asp 
            660                 665                 670


Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp Asn Ala Gln Thr 
        675                 680                 685


Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser Met Gln Lys Ser 
    690                 695                 700


Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr Thr Ala Ser Glu 
705                 710                 715                 720


Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly Ile Lys Leu Thr 
                725                 730                 735


Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser Pro Pro Lys Val 
            740                 745                 750


Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys Glu Glu Glu Lys 
        755                 760                 765


Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg Ile Ser Arg Pro 
    770                 775                 780


Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala Asp Lys Lys Arg 
785                 790                 795                 800


Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr Ala Leu Gln Lys 
                805                 810                 815


Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys Asp Thr Asn Ser 
            820                 825                 830


Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg Trp Thr Gly Ser 
        835                 840                 845


Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp Glu Ser Glu Gly 
    850                 855                 860


Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu Glu Glu Glu Lys 
865                 870                 875                 880


Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu Pro Cys Lys Lys 
                885                 890                 895


Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu Cys Asp Ser Cys 
            900                 905                 910


Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro Leu Met Ile Ile 
        915                 920                 925


Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His Lys Leu Leu Cys 
    930                 935                 940


Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val Ala Leu Lys Lys 
945                 950                 955                 960


Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val Tyr Val Gly Ile 
                965                 970                 975


Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp Phe Ser Glu Asp 
            980                 985                 990


Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys Ala Asn Leu Leu 
        995                 1000                1005


Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser Tyr Arg Phe Asp 
    1010                1015                1020


Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp Asp Ile Lys Glu 
1025                1030                1035                1040


Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile Ser Thr Ile Thr 
                1045                1050                1055


Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp Glu Glu Arg Lys 
            1060                1065                1070


Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg Arg Lys Lys Arg 
        1075                1080                1085


Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu Asp Glu Glu Glu 
    1090                1095                1100


Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln Asp Glu Phe Val 
1105                1110                1115                1120


Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp Pro Pro Ser Asn 
                1125                1130                1135


Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu Arg Arg His Pro 
            1140                1145                1150


Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg Lys Thr Pro Lys 
        1155                1160                1165


Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser Glu Glu Asn Ser 
    1170                1175                1180


Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser Asp Asp Phe Val 
1185                1190                1195                1200


Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys Arg Gln Ile Asn 
                1205                1210                1215


Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys Ser Leu Arg Arg 
            1220                1225                1230


Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu Ser Ser Ser Glu 
        1235                1240                1245


Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp Asp Glu Leu Ala 
    1250                1255                1260


Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg Ser Thr Asp Glu 
1265                1270                1275                1280


Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu Gly Lys Pro Ser 
                1285                1290                1295


Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu Glu Ser Cys Asp 
            1300                1305                1310


Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp Ser Gln Pro Arg 
        1315                1320                1325


Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro Tyr Arg Ile Glu 
    1330                1335                1340


Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys Val Gly Ser Pro 
1345                1350                1355                1360


Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn Gly Gln Ser Pro 
                1365                1370                1375


Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr Glu Lys Ser Gln 
            1380                1385                1390


Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu Ala Ser Asn Gly 
        1395                1400                1405


Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu Glu Glu Asp Glu 
    1410                1415                1420


Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys Asn Ser Glu Gln 
1425                1430                1435                1440


Leu 



<210>  7994
<211>  5318
<212>  DNA
<213>  Homo sapiens

<400>  7994
ctggtttatc aacttgacga gaatcatttc aaaattttag gaaaaaaatt tatgtctcag     60

taaaactttg tttagaatta ggtttttcag tagcaaggat aaggtgaagg gattaaaaat    120

gtacgtaaaa ttagtagtca atgaattctg gaatgcagtc tgtataatcc tattcagaga    180

ttatgctatt tactgaatat agctttggtt gtgtttaaat ctgcactagt attaggtgct    240

ccttaaaagt tgaaaatata tagccaataa ggtataaaga agaattgaca gataaatcta    300

aacagtttct ttgtatagta ctaacttctg aaatgttcag tggtggcatt tgataaagta    360

agttgtaata tgatcacatt gaggaatgtt atataattat taaactcaat ttttataaaa    420

ggcatcattt tataaaagta tcataagaaa gtgccaatgt ttcaatgaat aaattgaggc    480

aacatgatac caacttagtg aaaaatatac aagaccagaa ggaagtaacc taaaatatta    540

ctagtgattg cctctgggta ataggatatg ggctttttgt ctttctatat ttttcatttt    600

cccactgccg tgttcctggt acctcagtga aatgaagtgc tcagttcttt taacagttgt    660

cagtttttaa aacaaatata gtcttctgga aatgttttag gtagcatttt caattttatg    720

tttttaagcc atctcttgaa tttgaataaa ttatttgaac tgcataaata tttgcaatcc    780

attgagaaca ccaaaacaaa aagtaaaaag cagaaaccta aatttttcta aatttttttt    840

aatatctaga agttgtatct caaagttttt gtaattttct tcattgtcag attttatttt    900

ttactgtcaa atatccaatg acagaggcca cctcttttaa aatagaaact ttaaatggaa    960

atatacatta tactaagtct tatattttat agccttgaaa gtttctattc atgtaattaa   1020

gctttttctg atttttagag gaacagaaag aaagtgaaaa gatgaaaagt gaggagcagc   1080

ctatggattt agaaaaccgt tctacagcca atgttctaga agagactact gtgaaaaaag   1140

aaaaagaaga tgaaaaggaa cttgtgaaac tgccagtcat agtgaagcta gaaaaacctt   1200

tgccagaaaa tgaagaaaaa aagattatca aagaagaaag tgattccttc aaggaaaatg   1260

tcaaacccat taaagttgag gtgaaggaat gtagagcaga tcctaaagat accaaaagta   1320

gcatggagaa gccagtggca caggagcctg aaaggatcga atttggtggc aatattaaat   1380

cttctcacga aattactgag aaatctactg aagaaactga gaaacttaaa aatgaccagc   1440

aggccaagat accactaaaa aaacgagaaa ttaaactgag tgatgatttt gacagtccag   1500

tcaagggacc tttgtgtaaa tcagttactc caacaaaaga gtttttgaaa gatgaaataa   1560

aacaagagga agagacttgt aaaaggatct ctacaatcac tgctttgggt catgaaggga   1620

aacagctggt aaatggagaa gttagtgatg aaagggtagc tccaaatttt aagacagaac   1680

caatagagac aaagttttat gagacaaagg aagagagcta tagcccctct aaggacagaa   1740

atatcatcac ggagggaaat ggaacagagt ccttaaattc tgtcataaca agtatgaaaa   1800

caggtgagct tgagaaagaa acagcccctt tgaggaaaga tgcagatagt tcaatatcag   1860

tcttagagat ccatagtcaa aaagcacaaa tagaggaacc cgatcctcca gaaatggaaa   1920

cttctcttga ttcttctgag atggcaaaag atctctcttc aaaaactgct ttatcttcca   1980

ccgagtcgtg taccatgaaa ggtgaagaga agtctcccaa aactaagaag gataagcgcc   2040

caccaatcct agaatgtctt gaaaagttag agaagtccaa aaagactttt cttgataagg   2100

acgcacaaag attgagtcca ataccagaag aagttccaaa gagtactcta gagtcagaaa   2160

agcctggctc tcctgaggca gctgaaactt ctccaccatc taatatcatt gaccactgtg   2220

agaaactagc ctcagaaaaa gaagtggtag aatgccagag tacaagtact gttggtggcc   2280

agtctgtgaa aaaagtagac ctagaaaccc taaaagagga ttctgagttc acaaaggtag   2340

aaatggataa tctggacaat gcccagacct ctggcataga ggagccttct gagacaaagg   2400

gttctatgca aaaaagcaaa ttcaaatata agttggttcc tgaagaagaa accactgcct   2460

cagaaaatac agagataacc tctgaaaggc agaaagaggg catcaaatta acaatcagga   2520

tatcaagtcg gaaaaagaag cccgattctc cccccaaagt tctagaacca gaaaacaagc   2580

aagagaagac agaaaaggaa gaggagaaaa caaatgtggg tcgtacttta agaagatctc   2640

caagaatatc tagacccact gcaaaagtgg ctgagatcag agatcagaaa gctgataaaa   2700

aaagagggga aggagaagat gaggtggaag aagagtcaac agctttgcaa aaaactgaca   2760

aaaaggaaat tttgaaaaaa tcagagaaag atacaaattc taaagtaagc aaggtaaaac   2820

ccaaaggcaa agttcgatgg actggttctc ggacacgtgg cagatggaaa tattccagca   2880

atgatgaaag tgaagggtct ggcagtgaaa aatcatctgc agcttcagaa gaggaggaag   2940

aaaaggaaag tgaagaagcc atcctagcag atgatgatga accatgcaaa aaatgtggcc   3000

ttccaaacca tcctgagcta attcttctgt gtgactcttg cgatagtgga taccatactg   3060

cctgccttcg ccctcctctg atgatcatcc cagatggaga atggttctgc ccaccttgcc   3120

aacataaact gctctgtgaa aaattagagg aacagttgca ggatttggat gttgccttaa   3180

agaagaaaga gcgtgccgaa cgaagaaaag aacgcttggt gtatgttggt atcagtattg   3240

aaaacatcat tcctccacaa gagccagact tttctgaaga tcaagaagaa aagaaaaaag   3300

attcaaaaaa atccaaagca aacttgcttg aaaggaggtc aacaagaaca aggaaatgta   3360

taagctacag atttgatgag tttgatgaag caattgatga agctattgaa gatgacatca   3420

aagaagccga tggaggagga gttggccgag gaaaagatat ctccaccatc acaggtcatc   3480

gtgggaaaga catctctact attttggatg aagaaagaaa agaaaataaa cgaccccaga   3540

gggcagctgc tgctcgaagg aagaaacgcc ggcgattaaa tgatctggac agtgatagca   3600

acctggatga agaagagagc gaggatgaat tcaagatcag tgatggatct caagatgagt   3660

ttgttgtgtc tgatgaaaac ccagatgaaa gtgaagaaga tccgccatct aatgatgaca   3720

gtgacactga cttttgtagc cgtagactga ggcgacaccc ctctcggcca atgaggcaga   3780

gcaggcgttt gcgaagaaag accccaaaga aaaaatattc cgatgatgat gaagaggagg   3840

aatctgagga gaatagtaga gactctgaaa gtgacttcag tgatgatttt agtgatgatt   3900

ttgtagaaac tcggcgaagg cggtcaagga gaaatcagaa aagacaaatt aactacaaag   3960

aagactcaga aagtgacggt tcccagaaga gtttgcgacg tggtaaagaa ataaggcgag   4020

tacacaagcg aagactttcc agctcagaga gtgaagagag ctatttgtcc aagaactctg   4080

aagatgatga gctagctaaa gaatcaaagc ggtcagttcg aaagcggggc cgaagcacag   4140

acgagtattc agaagcagat gaggaggagg aggaagagga aggcaaacca tcccgcaaac   4200

ggctacaccg gattgagacg gatgaggagg agagttgtga caatgctcat ggagatgcaa   4260

atcagcctgc ccgtgacagc cagcctaggg tcctgccctc agaacaagag agcaccaaga   4320

agccctaccg gatagaaagt gatgaggaag aggactttga aaatgtaggc aaagtgggga   4380

gcccattgga ctatagctta gtggacttac cttcaaccaa tggacagagc cctggcaaag   4440

ccattgagaa cttgattggc aagcctactg agaagtctca gacccccaag gacaacagca   4500

cagccagtgc aagcctagcc tccaatggga caagtggtgg gcaggaggca ggagcaccag   4560

aagaggagga agatgagctt ttgagagtga ctgaccttgt tgattatgtc tgtaacagtg   4620

aacagttata agactttttt tccatttttg tgctaattta ttccacggta gctctcacac   4680

cagcgggcca gttattaaaa gctgtttaat ttttcctaga aaactccact acagaatgac   4740

ttttagaaga aaaatttcaa caaatcctga agtctttctg tgaagtgacc agttctgaac   4800

tttgaagata aataattgct gtaaattcct tttgattttc tttttccagg ttcatggtcc   4860

ttggtaattt cattcatgga aaaaaatctt attataataa caacaaagat ttgtatattt   4920

ttgactttat atttcctgag ctctcctgac tttgtgaaaa agggtggatg aaaatgcatt   4980

ccgaatctgt gagggcccaa aacagaattt aggggtgggt gaaagcactt gtgctttagc   5040

tttttcatat taaatatata ttatatttaa acattcatgg catagatgat gatttacaga   5100

caatttaaaa gttcaagtct gtactgttac agtttgagaa ttgtagataa catcatacat   5160

aagtcattta gtaacagcct ttgtgaaatg aacttgttta ctattggaga taaccacact   5220

taataaagaa gagacagtga aagtaccatc ataattaacc taaatttttg ttatagcaga   5280

gtttcttgtt taaaaaaaaa taaaatcatc tgaaaagc                           5318


<210>  7995
<211>  1189
<212>  PRT
<213>  Homo sapiens

<400>  7995

Met Lys Ser Glu Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala 
1               5                   10                  15


Asn Val Leu Glu Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys 
            20                  25                  30


Glu Leu Val Lys Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro 
        35                  40                  45


Glu Asn Glu Glu Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys 
    50                  55                  60


Glu Asn Val Lys Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp 
65                  70                  75                  80


Pro Lys Asp Thr Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro 
                85                  90                  95


Glu Arg Ile Glu Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr 
            100                 105                 110


Glu Lys Ser Thr Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala 
        115                 120                 125


Lys Ile Pro Leu Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp 
    130                 135                 140


Ser Pro Val Lys Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu 
145                 150                 155                 160


Phe Leu Lys Asp Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile 
                165                 170                 175


Ser Thr Ile Thr Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly 
            180                 185                 190


Glu Val Ser Asp Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile 
        195                 200                 205


Glu Thr Lys Phe Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys 
    210                 215                 220


Asp Arg Asn Ile Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser 
225                 230                 235                 240


Val Ile Thr Ser Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro 
                245                 250                 255


Leu Arg Lys Asp Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser 
            260                 265                 270


Gln Lys Ala Gln Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser 
        275                 280                 285


Leu Asp Ser Ser Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu 
    290                 295                 300


Ser Ser Thr Glu Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys 
305                 310                 315                 320


Thr Lys Lys Asp Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu 
                325                 330                 335


Glu Lys Ser Lys Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser 
            340                 345                 350


Pro Ile Pro Glu Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro 
        355                 360                 365


Gly Ser Pro Glu Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp 
    370                 375                 380


His Cys Glu Lys Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser 
385                 390                 395                 400


Thr Ser Thr Val Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr 
                405                 410                 415


Leu Lys Glu Asp Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp 
            420                 425                 430


Asn Ala Gln Thr Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser 
        435                 440                 445


Met Gln Lys Ser Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr 
    450                 455                 460


Thr Ala Ser Glu Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly 
465                 470                 475                 480


Ile Lys Leu Thr Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser 
                485                 490                 495


Pro Pro Lys Val Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys 
            500                 505                 510


Glu Glu Glu Lys Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg 
        515                 520                 525


Ile Ser Arg Pro Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala 
    530                 535                 540


Asp Lys Lys Arg Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr 
545                 550                 555                 560


Ala Leu Gln Lys Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys 
                565                 570                 575


Asp Thr Asn Ser Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg 
            580                 585                 590


Trp Thr Gly Ser Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp 
        595                 600                 605


Glu Ser Glu Gly Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu 
    610                 615                 620


Glu Glu Glu Lys Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu 
625                 630                 635                 640


Pro Cys Lys Lys Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu 
                645                 650                 655


Cys Asp Ser Cys Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro 
            660                 665                 670


Leu Met Ile Ile Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His 
        675                 680                 685


Lys Leu Leu Cys Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val 
    690                 695                 700


Ala Leu Lys Lys Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val 
705                 710                 715                 720


Tyr Val Gly Ile Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp 
                725                 730                 735


Phe Ser Glu Asp Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys 
            740                 745                 750


Ala Asn Leu Leu Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser 
        755                 760                 765


Tyr Arg Phe Asp Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp 
    770                 775                 780


Asp Ile Lys Glu Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile 
785                 790                 795                 800


Ser Thr Ile Thr Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp 
                805                 810                 815


Glu Glu Arg Lys Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg 
            820                 825                 830


Arg Lys Lys Arg Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu 
        835                 840                 845


Asp Glu Glu Glu Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln 
    850                 855                 860


Asp Glu Phe Val Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp 
865                 870                 875                 880


Pro Pro Ser Asn Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu 
                885                 890                 895


Arg Arg His Pro Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg 
            900                 905                 910


Lys Thr Pro Lys Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser 
        915                 920                 925


Glu Glu Asn Ser Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser 
    930                 935                 940


Asp Asp Phe Val Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys 
945                 950                 955                 960


Arg Gln Ile Asn Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys 
                965                 970                 975


Ser Leu Arg Arg Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu 
            980                 985                 990


Ser Ser Ser Glu Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp 
        995                 1000                1005


Asp Glu Leu Ala Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg 
    1010                1015                1020


Ser Thr Asp Glu Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu 
1025                1030                1035                1040


Gly Lys Pro Ser Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu 
                1045                1050                1055


Glu Ser Cys Asp Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp 
            1060                1065                1070


Ser Gln Pro Arg Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro 
        1075                1080                1085


Tyr Arg Ile Glu Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys 
    1090                1095                1100


Val Gly Ser Pro Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn 
1105                1110                1115                1120


Gly Gln Ser Pro Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr 
                1125                1130                1135


Glu Lys Ser Gln Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu 
            1140                1145                1150


Ala Ser Asn Gly Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu 
        1155                1160                1165


Glu Glu Asp Glu Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys 
    1170                1175                1180


Asn Ser Glu Gln Leu 
1185


<210>  7996
<211>  5312
<212>  DNA
<213>  Homo sapiens

<400>  7996
tttcattccc cctgtcacac gaggcagtgg caagcccgaa ggggaggaga gaagggggcg     60

gaaagagggc ggaaagtgaa aggcgccgag ggccgctctg tctcccgtct gactcggttc    120

tcgactgctc cgggccgccg atgtattgtg ggatcgcgga gccgtccctg agacgctggg    180

atccgcagag gagcccactt gagagcgcct cctgtcgtct gtaaggttgc cttgccatcc    240

ctcggcacca caacttcccc cgccccccca tcgcctcctc ctccatcctc cagttcaaaa    300

tggcgacggc ggcggcagcg gcggcggtga tggctcctcc gggctgcccg ggttcgtgcc    360

ccaacttcgc cgtagtctgc tccttcttgg agcgctacgg gccgctgcta gacctgcctg    420

agttgccgtt ccctgagctg gagcgggtgc tgcaggcgcc gccgccggac gtcggcaacg    480

gagaagtacc aaaagaattg gtggagctcc atttgaagct gatgaggaaa attggcaaat    540

ctgttactgc agacagatgg gaaaaatatt tgatcaagat atgccaagag tttaacagta    600

cctgggcatg ggagatggag aagaagggct atcttgaaat gagtgttgaa tgcaaactag    660

cactcttaaa gtacctctgt gagtgtcagt ttgatgacaa tctcaaattc aagaatatta    720

ttaatgagga ggatgccgat actatgcgtc tccagccaat tggtcgagac aaagatggcc    780

tcatgtactg gtaccaattg gatcaagatc acaatgtcag aatgtacata gaagaacaag    840

atgatcaaga tggctcttca tggaaatgca ttgtcagaaa tcgaaacgag ttggctgaga    900

ctcttgcact cctgaaagca caaattgatc ctgtactatt gaaaaactct agccaacaag    960

acaactcttc tcgggaaagt cccagcttag aggatgagga gactaaaaaa gaggaagaaa   1020

cacctaaaca agaggaacag aaagaaagtg aaaagatgaa aagtgaggag cagcctatgg   1080

atttagaaaa ccgttctaca gccaatgttc tagaagagac tactgtgaaa aaagaaaaag   1140

aagatgaaaa ggaacttgtg aaactgccag tcatagtgaa gctagaaaaa cctttgccag   1200

aaaatgaaga aaaaaagatt atcaaagaag aaagtgattc cttcaaggaa aatgtcaaac   1260

ccattaaagt tgaggtgaag gaatgtagag cagatcctaa agataccaaa agtagcatgg   1320

agaagccagt ggcacaggag cctgaaagga tcgaatttgg tggcaatatt aaatcttctc   1380

acgaaattac tgagaaatct actgaagaaa ctgagaaact taaaaatgac cagcaggcca   1440

agataccact aaaaaaacga gaaattaaac tgagtgatga ttttgacagt ccagtcaagg   1500

gacctttgtg taaatcagtt actccaacaa aagagttttt gaaagatgaa ataaaacaag   1560

aggaagagac ttgtaaaagg atctctacaa tcactgcttt gggtcatgaa gggaaacagc   1620

tggtaaatgg agaagttagt gatgaaaggg tagctccaaa ttttaagaca gaaccaatag   1680

agacaaagtt ttatgagaca aaggaagaga gctatagccc ctctaaggac agaaatatca   1740

tcacggaggg aaatggaaca gagtccttaa attctgtcat aacaagtatg aaaacaggtg   1800

agcttgagaa agaaacagcc cctttgagga aagatgcaga tagttcaata tcagtcttag   1860

agatccatag tcaaaaagca caaatagagg aacccgatcc tccagaaatg gaaacttctc   1920

ttgattcttc tgagatggca aaagatctct cttcaaaaac tgctttatct tccaccgagt   1980

cgtgtaccat gaaaggtgaa gagaagtctc ccaaaactaa gaaggataag cgcccaccaa   2040

tcctagaatg tcttgaaaag ttagagaagt ccaaaaagac ttttcttgat aaggacgcac   2100

aaagattgag tccaatacca gaagaagttc caaagagtac tctagagtca gaaaagcctg   2160

gctctcctga ggcagctgaa acttctccac catctaatat cattgaccac tgtgagaaac   2220

tagcctcaga aaaagaagtg gtagaatgcc agagtacaag tactgttggt ggccagtctg   2280

tgaaaaaagt agacctagaa accctaaaag aggattctga gttcacaaag gtagaaatgg   2340

ataatctgga caatgcccag acctctggca tagaggagcc ttctgagaca aagggttcta   2400

tgcaaaaaag caaattcaaa tataagttgg ttcctgaaga agaaaccact gcctcagaaa   2460

atacagagat aacctctgaa aggcagaaag agggcatcaa attaacaatc aggatatcaa   2520

gtcggaaaaa gaagcccgat tctcccccca aagttctaga accagaaaac aagcaagaga   2580

agacagaaaa ggaagaggag aaaacaaatg tgggtcgtac tttaagaaga tctccaagaa   2640

tatctagacc cactgcaaaa gtggctgaga tcagagatca gaaagctgat aaaaaaagag   2700

gggaaggaga agatgaggtg gaagaagagt caacagcttt gcaaaaaact gacaaaaagg   2760

aaattttgaa aaaatcagag aaagatacaa attctaaagt aagcaaggta aaacccaaag   2820

gcaaagttcg atggactggt tctcggacac gtggcagatg gaaatattcc agcaatgatg   2880

aaagtgaagg gtctggcagt gaaaaatcat ctgcagcttc agaagaggag gaagaaaagg   2940

aaagtgaaga agccatccta gcagatgatg atgaaccatg caaaaaatgt ggccttccaa   3000

accatcctga gctaattctt ctgtgtgact cttgcgatag tggataccat actgcctgcc   3060

ttcgccctcc tctgatgatc atcccagatg gagaatggtt ctgcccacct tgccaacata   3120

aactgctctg tgaaaaatta gaggaacagt tgcaggattt ggatgttgcc ttaaagaaga   3180

aagagcgtgc cgaacgaaga aaagaacgct tggtgtatgt tggtatcagt attgaaaaca   3240

tcattcctcc acaagagcca gacttttctg aagatcaaga agaaaagaaa aaagattcaa   3300

aaaaatccaa agcaaacttg cttgaaagga ggtcaacaag aacaaggaaa tgtataagct   3360

acagatttga tgagtttgat gaagcaattg atgaagctat tgaagatgac atcaaagaag   3420

ccgatggagg aggagttggc cgaggaaaag atatctccac catcacaggt catcgtggga   3480

aagacatctc tactattttg gatgaagaaa gaaaagaaaa taaacgaccc cagagggcag   3540

ctgctgctcg aaggaagaaa cgccggcgat taaatgatct ggacagtgat agcaacctgg   3600

atgaagaaga gagcgaggat gaattcaaga tcagtgatgg atctcaagat gagtttgttg   3660

tgtctgatga aaacccagat gaaagtgaag aagatccgcc atctaatgat gacagtgaca   3720

ctgacttttg tagccgtaga ctgaggcgac acccctctcg gccaatgagg cagagcaggc   3780

gtttgcgaag aaagacccca aagaaaaaat attccgatga tgatgaagag gaggaatctg   3840

aggagaatag tagagactct gaaagtgact tcagtgatga ttttagtgat gattttgtag   3900

aaactcggcg aaggcggtca aggagaaatc agaaaagaca aattaactac aaagaagact   3960

cagaaagtga cggttcccag aagagtttgc gacgtggtaa agaaataagg cgagtacaca   4020

agcgaagact ttccagctca gagagtgaag agagctattt gtccaagaac tctgaagatg   4080

atgagctagc taaagaatca aagcggtcag ttcgaaagcg gggccgaagc acagacgagt   4140

attcagaagc agatgaggag gaggaggaag aggaaggcaa accatcccgc aaacggctac   4200

accggattga gacggatgag gaggagagtt gtgacaatgc tcatggagat gcaaatcagc   4260

ctgcccgtga cagccagcct agggtcctgc cctcagaaca agagagcacc aagaagccct   4320

accggataga aagtgatgag gaagaggact ttgaaaatgt aggcaaagtg gggagcccat   4380

tggactatag cttagtggac ttaccttcaa ccaatggaca gagccctggc aaagccattg   4440

agaacttgat tggcaagcct actgagaagt ctcagacccc caaggacaac agcacagcca   4500

gtgcaagcct agcctccaat gggacaagtg gtgggcagga ggcaggagca ccagaagagg   4560

aggaagatga gcttttgaga gtgactgacc ttgttgatta tgtctgtaac agtgaacagt   4620

tataagactt tttttccatt tttgtgctaa tttattccac ggtagctctc acaccagcgg   4680

gccagttatt aaaagctgtt taatttttcc tagaaaactc cactacagaa tgacttttag   4740

aagaaaaatt tcaacaaatc ctgaagtctt tctgtgaagt gaccagttct gaactttgaa   4800

gataaataat tgctgtaaat tccttttgat tttctttttc caggttcatg gtccttggta   4860

atttcattca tggaaaaaaa tcttattata ataacaacaa agatttgtat atttttgact   4920

ttatatttcc tgagctctcc tgactttgtg aaaaagggtg gatgaaaatg cattccgaat   4980

ctgtgagggc ccaaaacaga atttaggggt gggtgaaagc acttgtgctt tagctttttc   5040

atattaaata tatattatat ttaaacattc atggcataga tgatgattta cagacaattt   5100

aaaagttcaa gtctgtactg ttacagtttg agaattgtag ataacatcat acataagtca   5160

tttagtaaca gcctttgtga aatgaacttg tttactattg gagataacca cacttaataa   5220

agaagagaca gtgaaagtac catcataatt aacctaaatt tttgttatag cagagtttct   5280

tgtttaaaaa aaaataaaat catctgaaaa gc                                 5312


<210>  7997
<211>  1441
<212>  PRT
<213>  Homo sapiens

<400>  7997

Met Ala Thr Ala Ala Ala Ala Ala Ala Val Met Ala Pro Pro Gly Cys 
1               5                   10                  15


Pro Gly Ser Cys Pro Asn Phe Ala Val Val Cys Ser Phe Leu Glu Arg 
            20                  25                  30


Tyr Gly Pro Leu Leu Asp Leu Pro Glu Leu Pro Phe Pro Glu Leu Glu 
        35                  40                  45


Arg Val Leu Gln Ala Pro Pro Pro Asp Val Gly Asn Gly Glu Val Pro 
    50                  55                  60


Lys Glu Leu Val Glu Leu His Leu Lys Leu Met Arg Lys Ile Gly Lys 
65                  70                  75                  80


Ser Val Thr Ala Asp Arg Trp Glu Lys Tyr Leu Ile Lys Ile Cys Gln 
                85                  90                  95


Glu Phe Asn Ser Thr Trp Ala Trp Glu Met Glu Lys Lys Gly Tyr Leu 
            100                 105                 110


Glu Met Ser Val Glu Cys Lys Leu Ala Leu Leu Lys Tyr Leu Cys Glu 
        115                 120                 125


Cys Gln Phe Asp Asp Asn Leu Lys Phe Lys Asn Ile Ile Asn Glu Glu 
    130                 135                 140


Asp Ala Asp Thr Met Arg Leu Gln Pro Ile Gly Arg Asp Lys Asp Gly 
145                 150                 155                 160


Leu Met Tyr Trp Tyr Gln Leu Asp Gln Asp His Asn Val Arg Met Tyr 
                165                 170                 175


Ile Glu Glu Gln Asp Asp Gln Asp Gly Ser Ser Trp Lys Cys Ile Val 
            180                 185                 190


Arg Asn Arg Asn Glu Leu Ala Glu Thr Leu Ala Leu Leu Lys Ala Gln 
        195                 200                 205


Ile Asp Pro Val Leu Leu Lys Asn Ser Ser Gln Gln Asp Asn Ser Ser 
    210                 215                 220


Arg Glu Ser Pro Ser Leu Glu Asp Glu Glu Thr Lys Lys Glu Glu Glu 
225                 230                 235                 240


Thr Pro Lys Gln Glu Glu Gln Lys Glu Ser Glu Lys Met Lys Ser Glu 
                245                 250                 255


Glu Gln Pro Met Asp Leu Glu Asn Arg Ser Thr Ala Asn Val Leu Glu 
            260                 265                 270


Glu Thr Thr Val Lys Lys Glu Lys Glu Asp Glu Lys Glu Leu Val Lys 
        275                 280                 285


Leu Pro Val Ile Val Lys Leu Glu Lys Pro Leu Pro Glu Asn Glu Glu 
    290                 295                 300


Lys Lys Ile Ile Lys Glu Glu Ser Asp Ser Phe Lys Glu Asn Val Lys 
305                 310                 315                 320


Pro Ile Lys Val Glu Val Lys Glu Cys Arg Ala Asp Pro Lys Asp Thr 
                325                 330                 335


Lys Ser Ser Met Glu Lys Pro Val Ala Gln Glu Pro Glu Arg Ile Glu 
            340                 345                 350


Phe Gly Gly Asn Ile Lys Ser Ser His Glu Ile Thr Glu Lys Ser Thr 
        355                 360                 365


Glu Glu Thr Glu Lys Leu Lys Asn Asp Gln Gln Ala Lys Ile Pro Leu 
    370                 375                 380


Lys Lys Arg Glu Ile Lys Leu Ser Asp Asp Phe Asp Ser Pro Val Lys 
385                 390                 395                 400


Gly Pro Leu Cys Lys Ser Val Thr Pro Thr Lys Glu Phe Leu Lys Asp 
                405                 410                 415


Glu Ile Lys Gln Glu Glu Glu Thr Cys Lys Arg Ile Ser Thr Ile Thr 
            420                 425                 430


Ala Leu Gly His Glu Gly Lys Gln Leu Val Asn Gly Glu Val Ser Asp 
        435                 440                 445


Glu Arg Val Ala Pro Asn Phe Lys Thr Glu Pro Ile Glu Thr Lys Phe 
    450                 455                 460


Tyr Glu Thr Lys Glu Glu Ser Tyr Ser Pro Ser Lys Asp Arg Asn Ile 
465                 470                 475                 480


Ile Thr Glu Gly Asn Gly Thr Glu Ser Leu Asn Ser Val Ile Thr Ser 
                485                 490                 495


Met Lys Thr Gly Glu Leu Glu Lys Glu Thr Ala Pro Leu Arg Lys Asp 
            500                 505                 510


Ala Asp Ser Ser Ile Ser Val Leu Glu Ile His Ser Gln Lys Ala Gln 
        515                 520                 525


Ile Glu Glu Pro Asp Pro Pro Glu Met Glu Thr Ser Leu Asp Ser Ser 
    530                 535                 540


Glu Met Ala Lys Asp Leu Ser Ser Lys Thr Ala Leu Ser Ser Thr Glu 
545                 550                 555                 560


Ser Cys Thr Met Lys Gly Glu Glu Lys Ser Pro Lys Thr Lys Lys Asp 
                565                 570                 575


Lys Arg Pro Pro Ile Leu Glu Cys Leu Glu Lys Leu Glu Lys Ser Lys 
            580                 585                 590


Lys Thr Phe Leu Asp Lys Asp Ala Gln Arg Leu Ser Pro Ile Pro Glu 
        595                 600                 605


Glu Val Pro Lys Ser Thr Leu Glu Ser Glu Lys Pro Gly Ser Pro Glu 
    610                 615                 620


Ala Ala Glu Thr Ser Pro Pro Ser Asn Ile Ile Asp His Cys Glu Lys 
625                 630                 635                 640


Leu Ala Ser Glu Lys Glu Val Val Glu Cys Gln Ser Thr Ser Thr Val 
                645                 650                 655


Gly Gly Gln Ser Val Lys Lys Val Asp Leu Glu Thr Leu Lys Glu Asp 
            660                 665                 670


Ser Glu Phe Thr Lys Val Glu Met Asp Asn Leu Asp Asn Ala Gln Thr 
        675                 680                 685


Ser Gly Ile Glu Glu Pro Ser Glu Thr Lys Gly Ser Met Gln Lys Ser 
    690                 695                 700


Lys Phe Lys Tyr Lys Leu Val Pro Glu Glu Glu Thr Thr Ala Ser Glu 
705                 710                 715                 720


Asn Thr Glu Ile Thr Ser Glu Arg Gln Lys Glu Gly Ile Lys Leu Thr 
                725                 730                 735


Ile Arg Ile Ser Ser Arg Lys Lys Lys Pro Asp Ser Pro Pro Lys Val 
            740                 745                 750


Leu Glu Pro Glu Asn Lys Gln Glu Lys Thr Glu Lys Glu Glu Glu Lys 
        755                 760                 765


Thr Asn Val Gly Arg Thr Leu Arg Arg Ser Pro Arg Ile Ser Arg Pro 
    770                 775                 780


Thr Ala Lys Val Ala Glu Ile Arg Asp Gln Lys Ala Asp Lys Lys Arg 
785                 790                 795                 800


Gly Glu Gly Glu Asp Glu Val Glu Glu Glu Ser Thr Ala Leu Gln Lys 
                805                 810                 815


Thr Asp Lys Lys Glu Ile Leu Lys Lys Ser Glu Lys Asp Thr Asn Ser 
            820                 825                 830


Lys Val Ser Lys Val Lys Pro Lys Gly Lys Val Arg Trp Thr Gly Ser 
        835                 840                 845


Arg Thr Arg Gly Arg Trp Lys Tyr Ser Ser Asn Asp Glu Ser Glu Gly 
    850                 855                 860


Ser Gly Ser Glu Lys Ser Ser Ala Ala Ser Glu Glu Glu Glu Glu Lys 
865                 870                 875                 880


Glu Ser Glu Glu Ala Ile Leu Ala Asp Asp Asp Glu Pro Cys Lys Lys 
                885                 890                 895


Cys Gly Leu Pro Asn His Pro Glu Leu Ile Leu Leu Cys Asp Ser Cys 
            900                 905                 910


Asp Ser Gly Tyr His Thr Ala Cys Leu Arg Pro Pro Leu Met Ile Ile 
        915                 920                 925


Pro Asp Gly Glu Trp Phe Cys Pro Pro Cys Gln His Lys Leu Leu Cys 
    930                 935                 940


Glu Lys Leu Glu Glu Gln Leu Gln Asp Leu Asp Val Ala Leu Lys Lys 
945                 950                 955                 960


Lys Glu Arg Ala Glu Arg Arg Lys Glu Arg Leu Val Tyr Val Gly Ile 
                965                 970                 975


Ser Ile Glu Asn Ile Ile Pro Pro Gln Glu Pro Asp Phe Ser Glu Asp 
            980                 985                 990


Gln Glu Glu Lys Lys Lys Asp Ser Lys Lys Ser Lys Ala Asn Leu Leu 
        995                 1000                1005


Glu Arg Arg Ser Thr Arg Thr Arg Lys Cys Ile Ser Tyr Arg Phe Asp 
    1010                1015                1020


Glu Phe Asp Glu Ala Ile Asp Glu Ala Ile Glu Asp Asp Ile Lys Glu 
1025                1030                1035                1040


Ala Asp Gly Gly Gly Val Gly Arg Gly Lys Asp Ile Ser Thr Ile Thr 
                1045                1050                1055


Gly His Arg Gly Lys Asp Ile Ser Thr Ile Leu Asp Glu Glu Arg Lys 
            1060                1065                1070


Glu Asn Lys Arg Pro Gln Arg Ala Ala Ala Ala Arg Arg Lys Lys Arg 
        1075                1080                1085


Arg Arg Leu Asn Asp Leu Asp Ser Asp Ser Asn Leu Asp Glu Glu Glu 
    1090                1095                1100


Ser Glu Asp Glu Phe Lys Ile Ser Asp Gly Ser Gln Asp Glu Phe Val 
1105                1110                1115                1120


Val Ser Asp Glu Asn Pro Asp Glu Ser Glu Glu Asp Pro Pro Ser Asn 
                1125                1130                1135


Asp Asp Ser Asp Thr Asp Phe Cys Ser Arg Arg Leu Arg Arg His Pro 
            1140                1145                1150


Ser Arg Pro Met Arg Gln Ser Arg Arg Leu Arg Arg Lys Thr Pro Lys 
        1155                1160                1165


Lys Lys Tyr Ser Asp Asp Asp Glu Glu Glu Glu Ser Glu Glu Asn Ser 
    1170                1175                1180


Arg Asp Ser Glu Ser Asp Phe Ser Asp Asp Phe Ser Asp Asp Phe Val 
1185                1190                1195                1200


Glu Thr Arg Arg Arg Arg Ser Arg Arg Asn Gln Lys Arg Gln Ile Asn 
                1205                1210                1215


Tyr Lys Glu Asp Ser Glu Ser Asp Gly Ser Gln Lys Ser Leu Arg Arg 
            1220                1225                1230


Gly Lys Glu Ile Arg Arg Val His Lys Arg Arg Leu Ser Ser Ser Glu 
        1235                1240                1245


Ser Glu Glu Ser Tyr Leu Ser Lys Asn Ser Glu Asp Asp Glu Leu Ala 
    1250                1255                1260


Lys Glu Ser Lys Arg Ser Val Arg Lys Arg Gly Arg Ser Thr Asp Glu 
1265                1270                1275                1280


Tyr Ser Glu Ala Asp Glu Glu Glu Glu Glu Glu Glu Gly Lys Pro Ser 
                1285                1290                1295


Arg Lys Arg Leu His Arg Ile Glu Thr Asp Glu Glu Glu Ser Cys Asp 
            1300                1305                1310


Asn Ala His Gly Asp Ala Asn Gln Pro Ala Arg Asp Ser Gln Pro Arg 
        1315                1320                1325


Val Leu Pro Ser Glu Gln Glu Ser Thr Lys Lys Pro Tyr Arg Ile Glu 
    1330                1335                1340


Ser Asp Glu Glu Glu Asp Phe Glu Asn Val Gly Lys Val Gly Ser Pro 
1345                1350                1355                1360


Leu Asp Tyr Ser Leu Val Asp Leu Pro Ser Thr Asn Gly Gln Ser Pro 
                1365                1370                1375


Gly Lys Ala Ile Glu Asn Leu Ile Gly Lys Pro Thr Glu Lys Ser Gln 
            1380                1385                1390


Thr Pro Lys Asp Asn Ser Thr Ala Ser Ala Ser Leu Ala Ser Asn Gly 
        1395                1400                1405


Thr Ser Gly Gly Gln Glu Ala Gly Ala Pro Glu Glu Glu Glu Asp Glu 
    1410                1415                1420


Leu Leu Arg Val Thr Asp Leu Val Asp Tyr Val Cys Asn Ser Glu Gln 
1425                1430                1435                1440


Leu 



<210>  7998
<211>  1052
<212>  DNA
<213>  Homo sapiens

<400>  7998
ataccatgac atcaccacag tcttaaaact tgtactgtta cgtagcaact tccatttctg     60

caagttgcaa aattaataat ataaatatag agacgttctt tgccgagagt cgtcggggtt    120

tcctgcttca acagtgcttg gacggaaccc ggtgctcgtc ccccacccca gccggccgcc    180

catagccagc cctccctcac ctcttcacgg caccctcaga ccgccccaag gcccctgccg    240

ccgccccagc gccacgcagc cactgccacc gccgccacct ctccttagtc gccgccatga    300

ggaccacgtc cacctcacag gtgcgccaga actaccacca ggactcagag gccgccatca    360

accgccagat caacctagag ctctgtgcct cctacgttta cctgtccatg tcttactgct    420

ttgaccgtga tgatgtggct ttgaagaact ttgccaaata ctttcttcac caatctcatg    480

aggagaggga gcatgctgag aaactgatga agctgcagaa ccaacgaggt ggccgaatct    540

tccttcagga tatcaaaaaa ccagactgtg atgactggga gagcgggctg aatgtgatgg    600

agtgtgcatt acatttggaa aaaaatgtga atcagtcact actggaactg cacaaattgg    660

ccactgacaa aaatgacccc catttgtgtg acttcattga gacacattac ctgaatgagc    720

aggtgaaagc catcaaagaa ttggatgacc atgtgaccaa cttgcacaag atgggagcac    780

tcgaatctgg cttggcagaa tatctctttg acaagcacac cctgggagac agtgataatg    840

aaagctaagc ctcggctaat ttccccgtag ccgtggggtg acttccctgg tcaccaaggc    900

agtgcatgca tgttggggtt tcctttacct tttctataag ttgtaccaaa acatccacct    960

aagttctttg atttgtgcca ttccttcaga tgaagaaatt tggtaccccc ccccaaaaaa   1020

agtaataata ataatataaa tatatgtatt ag                                 1052


<210>  7999
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  7999

Met Arg Thr Thr Ser Thr Ser Gln Val Arg Gln Asn Tyr His Gln Asp 
1               5                   10                  15


Ser Glu Ala Ala Ile Asn Arg Gln Ile Asn Leu Glu Leu Cys Ala Ser 
            20                  25                  30


Tyr Val Tyr Leu Ser Met Ser Tyr Cys Phe Asp Arg Asp Asp Val Ala 
        35                  40                  45


Leu Lys Asn Phe Ala Lys Tyr Phe Leu His Gln Ser His Glu Glu Arg 
    50                  55                  60


Glu His Ala Glu Lys Leu Met Lys Leu Gln Asn Gln Arg Gly Gly Arg 
65                  70                  75                  80


Ile Phe Leu Gln Asp Ile Lys Lys Pro Asp Cys Asp Asp Trp Glu Ser 
                85                  90                  95


Gly Leu Asn Val Met Glu Cys Ala Leu His Leu Glu Lys Asn Val Asn 
            100                 105                 110


Gln Ser Leu Leu Glu Leu His Lys Leu Ala Thr Asp Lys Asn Asp Pro 
        115                 120                 125


His Leu Cys Asp Phe Ile Glu Thr His Tyr Leu Asn Glu Gln Val Lys 
    130                 135                 140


Ala Ile Lys Glu Leu Asp Asp His Val Thr Asn Leu His Lys Met Gly 
145                 150                 155                 160


Ala Leu Glu Ser Gly Leu Ala Glu Tyr Leu Phe Asp Lys His Thr Leu 
                165                 170                 175


Gly Asp Ser Asp Asn Glu Ser 
            180


<210>  8000
<211>  614
<212>  DNA
<213>  Homo sapiens

<400>  8000
ttttcattcc ctaagaataa atgtgtactg attaatctca tgggagattg tttcataagc     60

atgtatcatt acattatttt ccttgtaatt aatttgctaa acggaggtga acaaagtagt    120

cctaaactaa aatttattta ccatttctcc tttaaataca aagacaaata tgatctattc    180

atgacattat accactgttt ctgttatttc ccatattaac ttggcgtagt tgtttaaaac    240

attcttttct tctttgtaga tgaagaaaat atgacagtga aataacgatt actattgatc    300

agtcatagtt gtttaaaata atgtctaatg ggctgggtgc ggtggttcac acctgtaatc    360

tcagcacttt gggaagccga ggtgggcaga ttatgcggtc aggagatcaa gaccatcctg    420

gccaacatgg tgaaacccca tctctactaa aataaaaaaa aaaaattagc tgggtttggt    480

ggcacacacc tgtaatccca gctactcggg aggctgtggc tggagaatcg cttgaaccag    540

caggtggagg ttgcagtgag ccaagatcac gccactgttc tccagcctgg gcaacacagc    600

gaggctccgt ctcc                                                      614


<210>  8001
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  8001

Met Ser Asn Gly Leu Gly Ala Val Val His Thr Cys Asn Leu Ser Thr 
1               5                   10                  15


Leu Gly Ser Arg Gly Gly Gln Ile Met Arg Ser Gly Asp Gln Asp His 
            20                  25                  30


Pro Gly Gln His Gly Glu Thr Pro Ser Leu Leu Lys 
        35                  40


<210>  8002
<211>  2984
<212>  DNA
<213>  Homo sapiens

<400>  8002
attgtgggat cgcggagccg tccctgagac gctgggatcc gcagaggagc ccacttgaga     60

gcgcctcctg tcgtctgtaa ggttgccttg ccatccctcg gcaccacaac ttcccccgcc    120

cccccatcgc ctcctcctcc atcctccagt tcaaaatggc gacggcggcg gcagcggcgg    180

cggtgatggc tcctccgggc tgcccgggtt cgtgccccaa cttcgccgta gtctgctcct    240

tcttggagcg ctacgggccg ctgctagacc tgcctgagtt gccgttccct gagctggagc    300

gggtgctgca ggcgccgccg ccggacgtcg gcaacggaga agtaccaaaa gaattggtgg    360

agctccattt gaagctgatg aggaaaattg gcaaatctgt tactgcagac agatgggaaa    420

aatatttgat caaggtaact agtatttgta aatttcctgc tctattactg aaatattact    480

ctagcataaa ttgatattat gttttataat acacataatt tttaattagt ttactaaaag    540

taagactatg gctccaaaat ccacatgact gcaagtatgt gattctcttc ttttgctact    600

acttagtagc agtcttgagt cctgaagtta gatttcagaa gtgttatatc tcttttgtgc    660

ctaacactgt gctcaggact tttcatgtct tttctcattt aattcttaaa atcaccctga    720

tcacatcaag taagaaacta ataaggctca gggatgttgt catttttact ttagttcaca    780

tagtatgcat agacttattt agtggttccc ctagactctg ttatatagaa cagaggtccc    840

caacccctgg gccacagacc aatagtggtc atccccattc ctctccttac catgtgagct    900

ctgcttcctc tgagatcagc tgcggcatag attctcatag gagtgcaaac cctatcgtga    960

actgcacatg cgaaggatct aggttgtgca ctccttatga gaatctactg actgatgatc   1020

cgtcactatc tcccatcact tccagatggg gccatctagt tgattcaaat gtaatgcatt   1080

tgaatcatcc ccaaaccatc tccctcccac ccaccacccc cagtctgtgg acaaattatc   1140

ttccgcaaaa ctggtccctg atgccagaaa ggttgaggac cactgataca gaaacatgcc   1200

atctttttcg ttcctcagaa tttttgcata tatggtatct tctgcctgga gtaccttccc   1260

accagtttgt tttcctagcc aacttatttg tcctttaggt ctcagctcaa gtagtactgt   1320

ctccttgagt ccttctctca ggaagatgtt ccttcatgga tttatgttta accctatttt   1380

agaaactgtc atatggtttt atattgaatg ttcattatgt accaggcgct gtttagtgct   1440

tcctttgcat tatctcaact ttaaaatact gattatcctc attttactca caaggaaatt   1500

gattttgaga aactaaatag agtaacttgt ctggtctcac attgctaaaa acgacagagc   1560

cagcattcaa atccaggact tggtgaatcc agtactttaa aatatcactg atgaaatgtt   1620

cctcacattt gtcttttgtg tatattgtaa gtttcttgaa ggcttctttt aatctttttt   1680

tttttttttt taaagacagt ctcactctgt cacccaggct agagtgcagt ggtgctgtct   1740

cggctcactg caacgtccac ctcctgggtt caagcaattc tcttgcttca gcctcctgag   1800

tagctgggac tacaggtgcg tgccaccatg cctggctaat tttttttgta ttattagtag   1860

agacagggtt tcaccatatt ggccaggcta gtctcgaact cctgacctcg tgatccgccc   1920

acctcggcct cccaaagtgc tgggattaca ggcgtgagcc accgtgcccg gcggcttctt   1980

ttaatctttt atgcatcagt attagatgga tcaattaatc actgagacaa ttttagtttt   2040

ctttcccttg actgccagta agcttaactt tgttatattt atttattagt tataatcatt   2100

agctagtttt ctgatggaat ttttaccttc cctgttacat ggctcttaca gtgctctcgt   2160

ctttctcctt gtggcatcat tgtacatatg tattactgaa agctgtttct tttccttttg   2220

aagtaaatgg aatataatta atataaaatt ctgtttaaat ccagagcaag tatctggcat   2280

ctgctaggcc ttgttgcttt gctcatagca gacattacca acctaagcct tcctgctaag   2340

cctagactta gcagactaca ttattacaca aatcagtcag cattggcatc tatttgtcat   2400

ctattgttag taattcccta agacagctga actaagacct atagaatgag cagaaatttt   2460

gttaggaaat aaccagtagc ttagccctac tgtaatagaa agtaccttga gaaaatgaca   2520

gtgagtggag gcctaacagt catgtgttca ggaggttact gtgataatcc aactgagcaa   2580

taaggagacc tgaattaagg ttttggcact agggatggaa aggagggggt ggatgtaaga   2640

gctatttgga aggtaaaatc aacaactatt gataattgat agtgagagag aaagagagag   2700

aggtgtctag gaactgagct taaccaaggg cattcatttg ttattgtgct gtatcttgca   2760

tttgctaacg tacattcatc cgtagtagac aggacctcaa aaatctaggc ggatgacttt   2820

ttactttgac agcggaatta cccttctaaa aataaggaaa cccagctagg cacagtggct   2880

cacatgtgta atcctagcac tttgggaggc tgaggcaggt agattgcttg agctcaggag   2940

ttcgagacca gcctgggcaa catggcaaaa tcccatctct acaa                    2984


<210>  8003
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  8003

Met Ala Thr Ala Ala Ala Ala Ala Ala Val Met Ala Pro Pro Gly Cys 
1               5                   10                  15


Pro Gly Ser Cys Pro Asn Phe Ala Val Val Cys Ser Phe Leu Glu Arg 
            20                  25                  30


Tyr Gly Pro Leu Leu Asp Leu Pro Glu Leu Pro Phe Pro Glu Leu Glu 
        35                  40                  45


Arg Val Leu Gln Ala Pro Pro Pro Asp Val Gly Asn Gly Glu Val Pro 
    50                  55                  60


Lys Glu Leu Val Glu Leu His Leu Lys Leu Met Arg Lys Ile Gly Lys 
65                  70                  75                  80


Ser Val Thr Ala Asp Arg Trp Glu Lys Tyr Leu Ile Lys Val Thr Ser 
                85                  90                  95


Ile Cys Lys Phe Pro Ala Leu Leu Leu Lys Tyr Tyr Ser Ser Ile Asn 
            100                 105                 110


<210>  8004
<211>  743
<212>  DNA
<213>  Homo sapiens

<400>  8004
gttcaaaatg gcgacggcgg cggcagcggc ggcggtgatg gctcctccgg gctgcccggg     60

ttcgtgcccc aacttcgccg tagtctgctc cttcttggag cgctacgggc cgctgctaga    120

cctgcctgag ttgccgttcc ctgagctgga gcgggtgctg caggcgccgc cgccggacgt    180

cggcaacgga gaagtcggtc aggaagccgt gcagcagcta tggctttgaa ggttaccgga    240

aaaacacgcg tggagctgga ggtggcagtt caccgaaatt gaatcactct aacgagccgc    300

aacataaaat ccctggaaaa ggtgtgtgct gacttcatca gaggagcaga ggcaaagaat    360

ctccaagtga aaggaccagt tcgaatacct accaagactt tgagaatcac tacagaaaaa    420

gtccttgtgg tgaaggttct aagacgtggg atcctttcca gatgagaatc cacaagcgac    480

tcattgactt gcacagtcct tctgagattg ttaagcagat tgcttccatc agtttgagcc    540

gggagttgag gtgaaagtca ccattgcaga tgcttaagtc aactatttta ataaattgat    600

taccagttgt taaaaaaaaa ttataaatgg cagacttgat cccattcatc attagactac    660

tttcatgttt tgctcagaat taagtaagtt ttaatattca tttaaaaata cttatcaaat    720

aaatttggtt tctctcaaag taa                                            743


<210>  8005
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  8005

Met Ala Thr Ala Ala Ala Ala Ala Ala Val Met Ala Pro Pro Gly Cys 
1               5                   10                  15


Pro Gly Ser Cys Pro Asn Phe Ala Val Val Cys Ser Phe Leu Glu Arg 
            20                  25                  30


Tyr Gly Pro Leu Leu Asp Leu Pro Glu Leu Pro Phe Pro Glu Leu Glu 
        35                  40                  45


Arg Val Leu Gln Ala Pro Pro Pro Asp Val Gly Asn Gly Glu Val Gly 
    50                  55                  60


Gln Glu Ala Val Gln Gln Leu Trp Leu 
65                  70


<210>  8006
<211>  582
<212>  DNA
<213>  Homo sapiens

<400>  8006
gttcaactgc agggcgtatt cccggagggc agttggggag cgcagatccc gaagcagcgc     60

tgggagcgta agtgcgggca gagcactgcg ccgtttggga acgcaacttt gaggagacag    120

tgcggtggac ttcagtgaag ttccttatga cttcccctga aattgcttcc ttatcatggg    180

ggcaaatgaa agtaaaaggc tctaatacaa cctataagga ctgcaaagta tggccagggg    240

gtagtcggac ttgggattgg agagaaacag gaactgagca ttctcctggt gtgcagcctg    300

cagatgtgaa ggaagttgtt gagaagggtg tacagactct tgtgattggc cgagggatga    360

gtgaggcctt gaagggtctt actctgccac ccaggctgga gtgcagtggc acgatcataa    420

ctcactgaag cctcaaactc ctgggcgcaa gtgatcttcc tgcctcagcc tcctgaggag    480

tggggattac aggcacgtgc caccacgcca ggagctggac tgagcatcaa acatgtctgt    540

gagctggcaa tgagtcacct aagtactttt ttgtatcaaa tc                       582


<210>  8007
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  8007

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His Ser Pro Gly 
        35                  40                  45


Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly Val Gln Thr 
    50                  55                  60


Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Gly Leu Thr Leu 
65                  70                  75                  80


Pro Pro Arg Leu Glu Cys Ser Gly Thr Ile Ile Thr His 
                85                  90


<210>  8008
<211>  588
<212>  DNA
<213>  Homo sapiens

<400>  8008
gtattcccgg agggcagttg gggagcgcag atcccgaagc agcgctggga gcgtaagtgc     60

gggcagagca ctgcgccgtt tgggaacgca actttgagga gacagtgcgg tggttctgga    120

ggctgggaag tccaagacca gttggctcgc atctgacttc agtgaagttc cttatgactt    180

cccctgaaat tgcttcctta tcatgggggc aaatgaaagt aaaaggctct aatacaacct    240

ataaggactg caaagtatgg ccagggggta gtcggacttg ggattggaga gaaacaggaa    300

ctgagcattc tcctggtgtg cagcctgcag atgtgaagga agttgttgag aagggtgtac    360

agactcttgt gattggccga gggatgagtg aggccttgaa ggtgccttca tcaactgtgg    420

agtacctcaa gaaacatggc attgatgtgc gggtcctcca gacagagcag gcagtgaagg    480

agtataatgc cttggttgcc caaggggtca gggtgggagg tgtcttccat tccacctgct    540

gatggagcct taagaggaga ataaatcact aagtgcctat gcctgtga                 588


<210>  8009
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  8009

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His Ser Pro Gly 
        35                  40                  45


Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly Val Gln Thr 
    50                  55                  60


Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Val Pro Ser Ser 
65                  70                  75                  80


Thr Val Glu Tyr Leu Lys Lys His Gly Ile Asp Val Arg Val Leu Gln 
                85                  90                  95


Thr Glu Gln Ala Val Lys Glu Tyr Asn Ala Leu Val Ala Gln Gly Val 
            100                 105                 110


Arg Val Gly Gly Val Phe His Ser Thr Cys 
        115                 120


<210>  8010
<211>  534
<212>  DNA
<213>  Homo sapiens

<400>  8010
ggcagttggg gagcgcagat cccgaagcag cgctgggagc gtaagtgcgg gcagagcact     60

gcgccgtttg ggaacgcaac tttgaggaga cagtgcggtg gacttcagtg aagttcctta    120

tgacttcccc tgaaattgct tccttatcat gggggcaaat gaaagtaaaa ggctctaata    180

caacctataa ggactgcaaa gtatggccag ggggtagtcg gacttgggat tggagagaaa    240

caggaactga gcattctcct ggtgtgcagc ctgcagatgt gaaggaagtt gttgagaagg    300

gtgtacagac tcttgtgatt ggccgaggga tgagtgaggc cttgaaggtg ccttcatcaa    360

ctgtggagta cctcaagaaa catggcattg atgtgcgggt cctccagaca gagcaggcag    420

tgaaggagta taatgccttg gttgcccaag gggtcagggt gggaggtgtc ttccattcca    480

cctgctgatg gagccttaag aggagaataa atcactaagt gcctatgcct gtga          534


<210>  8011
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  8011

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His Ser Pro Gly 
        35                  40                  45


Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly Val Gln Thr 
    50                  55                  60


Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Val Pro Ser Ser 
65                  70                  75                  80


Thr Val Glu Tyr Leu Lys Lys His Gly Ile Asp Val Arg Val Leu Gln 
                85                  90                  95


Thr Glu Gln Ala Val Lys Glu Tyr Asn Ala Leu Val Ala Gln Gly Val 
            100                 105                 110


Arg Val Gly Gly Val Phe His Ser Thr Cys 
        115                 120


<210>  8012
<211>  455
<212>  DNA
<213>  Homo sapiens

<400>  8012
gcagttgggg agcgcagatc ccgaagcagc gctgggagcg taagtgcggg cagagcactg     60

cgccgtttgg gaacgcaact ttgaggagac agtgcggtgg agatgaggtt tcaccatgtt    120

ggccagtctg gtcttgaact cctgacctca agtgatccac ccacttcggc ctctcagaag    180

tgctgggatt acaggcatga gccaccacgc ctggccagtt ctggaggctg ggaagtccaa    240

gaccagttgg ctcgcatctg gtgagagcct tcttgctgca tcatcctata gtggaagtca    300

tcacatggtg gaagcaccaa gagagggcca tacttgtcct tttataatga acctactact    360

cctgcaataa cagcataatc tattcatgag ggtggaaccc tcatggccta atcagctctt    420

aaaggtccca cctcttaatg ttgttataat ggcag                               455


<210>  8013
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8013

Met Ser His His Ala Trp Pro Val Leu Glu Ala Gly Lys Ser Lys Thr 
1               5                   10                  15


Ser Trp Leu Ala Ser Gly Glu Ser Leu Leu Ala Ala Ser Ser Tyr Ser 
            20                  25                  30


Gly Ser His His Met Val Glu Ala Pro Arg Glu Gly His Thr Cys Pro 
        35                  40                  45


Phe Ile Met Asn Leu Leu Leu Leu Gln 
    50                  55


<210>  8014
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  8014
gcagatcccg aagcagcgct gggagcgtaa gtgcgggcag agcactgcgc cgtttgggaa     60

cgcaactttg aggagacagt gcggtggttc tggaggctgg gaagtccaag accagttggc    120

tcgcatctga cttcagtgaa gttccttatg acttcccctg aaattgcttc cttatcatgg    180

gggcaaatga aagtaaaagg ctctaataca acctataagg actgcaaagt atggccaggg    240

ggtagtcgga cttgggattg gagagaaaca ggaactgagc attctcctgg tgtgcagcct    300

gcagatgtga aggaagttgt tgagaagggt gtacagactc ttgtgattgg ccgagggatg    360

agtgaggcct tgaaggctcc aacccagcag ctgccatcag gtgttcatgt cagggctgtg    420

gtacaattcc acctggctac agcttcatgg cacatccttg agagatgcaa aacaggagct    480

ggactgagca tcaaacatgt ctgtgagctg gcaatgagtc acctaagtac ttttttgtat    540

caaatctatg atgccatcat tcttaagatg cacctttatt ttatgaaat                589


<210>  8015
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  8015

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His Ser Pro Gly 
        35                  40                  45


Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly Val Gln Thr 
    50                  55                  60


Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Ala Pro Thr Gln 
65                  70                  75                  80


Gln Leu Pro Ser Gly Val His Val Arg Ala Val Val Gln Phe His Leu 
                85                  90                  95


Ala Thr Ala Ser Trp His Ile Leu Glu Arg Cys Lys Thr Gly Ala Gly 
            100                 105                 110


Leu Ser Ile Lys His Val Cys Glu Leu Ala Met Ser His Leu Ser Thr 
        115                 120                 125


Phe Leu Tyr Gln Ile Tyr Asp Ala Ile Ile Leu Lys Met His Leu Tyr 
    130                 135                 140


Phe Met 
145


<210>  8016
<211>  612
<212>  DNA
<213>  Homo sapiens

<400>  8016
gtaagtgcgg gcagagcact gcgccgtttg ggaacgcaac tttgaggaga cagtgcggtg     60

gagatgaggt ttcaccatgt tggccagtct ggtcttgaac tcctgacctc aagtgatcca    120

cccacttcgg cctctcagaa gtgctgggat tacaggcatg agccaccacg cctggccaga    180

cttcagtgaa gttccttatg acttcccctg aaattgcttc cttatcatgg gggcaaatga    240

aagtaaaagg ctctaataca acctataagg actgcaaagt atggccaggg ggtagtcgga    300

cttgggattg gagagaaaca ggaactgagc attctcctgg tgtgcagcct gcagatgtga    360

aggaagttgt tgagaagggt gtacagactc ttgtgattgg ccgagggatg agtgaggcct    420

tgaaggtgcc ttcatcaact gtggagtacc tcaagaaaca tggcattgat gtgcgggtcc    480

tccagacaga gcaggcagtg aaggagtata atgccttggt tgcccaaggg gtcagggtgg    540

gaggtgtctt ccattccacc tgctgatgga gccttaagag gagaataaat cactaagtgc    600

ctatgcctgt ga                                                        612


<210>  8017
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  8017

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His Ser Pro Gly 
        35                  40                  45


Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly Val Gln Thr 
    50                  55                  60


Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Val Pro Ser Ser 
65                  70                  75                  80


Thr Val Glu Tyr Leu Lys Lys His Gly Ile Asp Val Arg Val Leu Gln 
                85                  90                  95


Thr Glu Gln Ala Val Lys Glu Tyr Asn Ala Leu Val Ala Gln Gly Val 
            100                 105                 110


Arg Val Gly Gly Val Phe His Ser Thr Cys 
        115                 120


<210>  8018
<211>  425
<212>  DNA
<213>  Homo sapiens

<400>  8018
gcgggcagag cactgcgccg tttgggaacg caactttgag gagacagtgc ggtggttctg     60

gaggctggga agtccaagac cagttggctc gcatctgact tcagtgaagt tccttatgac    120

ttcccctgaa attgcttcct tatcatgggg gcaaatgaaa gtaaaaggct ctaatacaac    180

ctataaggac tgcaaagtat ggccaggggg tagtcggact tgggattgga gagaaacagg    240

aactgaggtg ccttcatcaa ctgtggagta cctcaagaaa catggcattg atgtgcgggt    300

cctccagaca gagcaggcag tgaaggagta taatgccttg gttgcccaag gggtcagggt    360

gggaggtgtc ttccattcca cctgctgatg gagccttaag aggagaataa atcactaagt    420

gccta                                                                425


<210>  8019
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  8019

Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln Met Lys Val 
1               5                   10                  15


Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp Pro Gly Gly 
            20                  25                  30


Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu Val Pro Ser Ser 
        35                  40                  45


Thr Val Glu Tyr Leu Lys Lys His Gly Ile Asp Val Arg Val Leu Gln 
    50                  55                  60


Thr Glu Gln Ala Val Lys Glu Tyr Asn Ala Leu Val Ala Gln Gly Val 
65                  70                  75                  80


Arg Val Gly Gly Val Phe His Ser Thr Cys 
                85                  90


<210>  8020
<211>  585
<212>  DNA
<213>  Homo sapiens

<400>  8020
cattatactc cttcactgcc tgctctgtct ggaggacccg cacatcaatg ccatgtttct     60

tgaggtactc cacagttgat gaaggcacct gggaaggtgg aaaagagatg agtacagggt    120

cttgctctgt tgcctaagct ggagtgcaat ggcacaatca gcttaccaca gcctcaaaat    180

cctgggctca agtgattttc ccacctcagg ctcctgagca gctaggacta caggtgtgca    240

tcaccatgtc tggctataaa aaagaatttt gtagagatgg ggtctcacta tgtttcccag    300

gatggtctca aattcctggc ctcaagtgat cctccggcct tggtctccaa aagtgctggg    360

attacaagca tgaacaactg tgcccagact tgattttctt tcttaagccc cacatttgaa    420

ctgatggtct tgactttttg atacatgttt ttgtaaagca cacaagtttt taattttgat    480

gaggtctatt aatttatttt tccttttgtt gcttgtggat ttggtgttat ttctaagaat    540

ccattgccat atccaaggtc ttaaagattt acccttgttt tcttc                    585


<210>  8021
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  8021

Met Gly Ser His Tyr Val Ser Gln Asp Gly Leu Lys Phe Leu Ala Ser 
1               5                   10                  15


Ser Asp Pro Pro Ala Leu Val Ser Lys Ser Ala Gly Ile Thr Ser Met 
            20                  25                  30


Asn Asn Cys Ala Gln Thr 
        35


<210>  8022
<211>  628
<212>  DNA
<213>  Homo sapiens

<400>  8022
gggaagtcca agaccagttg gctcgcatct ggtgagagcc ttcttgctgc atcatcctat     60

agtggaagtc atcacatggt ggaagcacca agagagggcc atacttgtcc ttttataatg    120

aacctactac tcctgcaata acagcataat ctattcatga gggtggaacc ctcatggcct    180

aatcagctct taaagacttc agtgaagttc cttatgactt cccctgaaat tgcttcctta    240

tcatgggggc aaatgaaagt aaaaggctct aatacaacct ataaggactg caaagtatgg    300

ccagggggta gtcggacttg ggattggaga gaaacaggaa ctgagcattc tcctggtgtg    360

cagcctgcag atgtgaagga agttgttgag aagggtgtac agactcttgt gattggccga    420

gggatgagtg aggccttgaa ggtgccttca tcaactgtgg agtacctcaa gaaacatggc    480

attgatgtgc gggtcctcca gacagagcag gcagtgaagg agtataatgc cttggttgcc    540

caaggggtca gggtgggagg tgtcttccat tccacctgct gatggagcct taagaggaga    600

ataaatcact aagtgcctat gcctgtga                                       628


<210>  8023
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8023

Met Arg Val Glu Pro Ser Trp Pro Asn Gln Leu Leu Lys Thr Ser Val 
1               5                   10                  15


Lys Phe Leu Met Thr Ser Pro Glu Ile Ala Ser Leu Ser Trp Gly Gln 
            20                  25                  30


Met Lys Val Lys Gly Ser Asn Thr Thr Tyr Lys Asp Cys Lys Val Trp 
        35                  40                  45


Pro Gly Gly Ser Arg Thr Trp Asp Trp Arg Glu Thr Gly Thr Glu His 
    50                  55                  60


Ser Pro Gly Val Gln Pro Ala Asp Val Lys Glu Val Val Glu Lys Gly 
65                  70                  75                  80


Val Gln Thr Leu Val Ile Gly Arg Gly Met Ser Glu Ala Leu Lys Val 
                85                  90                  95


Pro Ser Ser Thr Val Glu Tyr Leu Lys Lys His Gly Ile Asp Val Arg 
            100                 105                 110


Val Leu Gln Thr Glu Gln Ala Val Lys Glu Tyr Asn Ala Leu Val Ala 
        115                 120                 125


Gln Gly Val Arg Val Gly Gly Val Phe His Ser Thr Cys 
    130                 135                 140


<210>  8024
<211>  13557
<212>  DNA
<213>  Homo sapiens

<400>  8024
taggaatatt actaaccacc agtgcccttt ggcctttgct gtcagcttcc tcggtgccca     60

tcactggagg aggcctcctc aagaccactc ggccctgagt gcggcgagga ccctgtttgt    120

ggatgtggag gagcgcgggc cggaggccat ggacgtgaag gagaggaagc cttaccgctc    180

gctgacccgg cgccgcgacg ccgagcgccg ctacaccagc tcgtccgcgg acagcgagga    240

gggcaaagcc ccgcagaaat cgtacagctc cagcgagacc ctgaaggcct acgaccagga    300

cgcccgccta gcctatggca gccgcgtcaa ggacattgtg ccgcaggagg ccgaggaatt    360

ctgccgcaca ggtgccaact tcaccctgcg ggagctgggg ctggaagaag taacgccccc    420

tcacgggacc ctgtaccgga cagacattgg cctcccccac tgcggctact ccatgggggc    480

tggctctgat gccgacatgg aggctgacac ggtgctgtcc cctgagcacc ccgtgcgtct    540

gtggggccgg agcacacggt cagggcgcag ctcctgcctg tccagccggg ccaattccaa    600

tctcacactc accgacaccg agcatgaaaa cactgagact gatcatccgg gcggcctgca    660

gaaccacgcg cggctccgga cgccgccgcc gccgctctcg cacgcccaca cccccaacca    720

gcaccacgcg gcctccatta actccctgaa ccggggcaac ttcacgccga ggagcaaccc    780

cagcccggcc cccacggacc actcgctctc cggagagccc cctgccggcg gcgcccagga    840

gcctgcccac gcccaggaga actggctgct caacagcaac atccccctgg agaccagaaa    900

cctaggcaag cagccattcc tagggacatt gcaggacaac ctcattgaga tggacattct    960

cggcgcctcc cgccatgatg gggcttacag tgacgggcac ttcctcttca agcctggagg   1020

cacctccccg ctcttctgca ccacatcacc agggtaccca ctgacgtcca gcacagtgta   1080

ctctcctccg ccccgacccc tgccccgcag caccttcgcc cggccggcct ttaacctcaa   1140

gaagccctcc aagtactgta actggaagtg cgcagccctg agcgccatcg tcatctcagc   1200

cactctggtc atcctgctgg catactttgt ggccatgcac ctgtttggcc taaactggca   1260

cctgcagccg atggaggggc agatgtatga gatcacggag gacacagcca gcagttggcc   1320

tgtgccaacc gacgtctccc tatacccctc agggggcact ggcttagaga cccctgacag   1380

gaaaggcaaa ggaaccacag aaggaaagcc cagtagtttc tttccagagg acagtttcat   1440

agattctgga gaaattgatg tgggaaggcg agcttcccag aagattcctc ctggcacttt   1500

ctggagatct caagtgttca tagaccatcc tgtgcatctg aaattcaatg tgtctctggg   1560

aaaggcagcc ctggttggca tttatggcag aaaaggcctc cctccttcac atacacagtt   1620

tgactttgtg gagctgctgg atggcaggag gctcctaacc caggaggcgc ggagcctaga   1680

ggggaccccg cgccagtctc ggggaactgt gcccccctcc agccatgaga caggcttcat   1740

ccagtatttg gattcaggaa tctggcactt ggctttttac aatgacggaa aggagtcaga   1800

agtggtttcc tttctcacca ctgccattga gtcggtggat aactgcccca gcaactgcta   1860

tggcaatggt gactgcatct ctgggacctg ccactgcttc ctgggtttcc tgggccccga   1920

ctgtggcaga gcctcctgcc ccgtgctctg tagcggaaat ggccaataca tgaaaggcag   1980

atgcttgtgc cacagtggct ggaaaggcgc tgagtgcgat gtgcccacca accagtgtat   2040

cgatgtggcc tgcagcaacc atggcacctg catcacgggc acctgcatct gcaaccctgg   2100

ctacaagggc gagagctgtg aggaagtgga ctgcatggac cccacatgtt caggccgggg   2160

tgtctgcgtg agaggcgaat gccactgctc tgtgggatgg ggaggcacca actgcgagac   2220

ccccagggcc acatgcttag accagtgttc aggccacgga accttcctcc cggacaccgg   2280

gctttgcagc tgtgacccaa gctggactgg acacgactgt tctatcgaga tctgtgctgc   2340

cgactgtggt ggccatggcg tgtgcgtagg gggcacctgc cgctgcgagg atggctggat   2400

gggggcagcc tgcgaccagc gggcctgcca cccgcgctgt gccgagcatg ggacctgccg   2460

cgacggcaag tgcgagtgca gccctggctg gaatggcgaa cactgcacca tcgctcacta   2520

tctggatagg gtagttaaag agggttgccc tgggttgtgc aatggcaacg gcagatgtac   2580

cttagacctg aatggttggc actgcgtctg ccagctgggc tggagaggag ctggctgtga   2640

cacttccatg gagactgcct gcggtgacag caaagacaat gatggagatg gcctggtgga   2700

ctgcatggac cctgactgct gcctccagcc cctgtgccat atcaacccgc tgtgccttgg   2760

ctcccctaac cctctggaca tcatccagga gacacaggtc cctgtgtcac agcagaacct   2820

acactccttc tatgaccgca tcaagttcct cgtgggcagg gacagcacgc acataatccc   2880

cggggagaac ccctttgatg gagggcatgc ttgtgttatt cgtggccaag tgatgacatc   2940

agatggaacc cccctggttg gtgtgaacat cagttttgtc aataaccctc tctttggata   3000

tacaatcagc aggcaagatg gcagctttga cttggtgaca aatggcggca tctccatcat   3060

cctgcggttc gagcgggcac ctttcatcac acaggagcac accctgtggc tgccatggga   3120

tcgcttcttt gtcatggaaa ccatcatcat gagacatgag gagaatgaga ttcccagctg   3180

tgacctgagc aattttgccc gccccaaccc agtcgtctct ccatccccac tgacgtcctt   3240

cgccagctcc tgtgcagaga aaggccccat tgtgccggaa attcaggctt tgcaggagga   3300

aatctctatc tctggctgca agatgaggct gagctacctg agcagccgga cccctggcta   3360

caaatctgtc ctgaggatca gcctcaccca cccgaccatc cccttcaacc tcatgaaggt   3420

gcacctcatg gtagcggtgg agggccgcct cttcaggaag tggttcgctg cagccccaga   3480

cctgtcctat tatttcattt gggacaagac agacgtctac aaccagaagg tgtttgggct   3540

ttcagaagcc tttgtttccg tgggttatga atatgaatcc tgcccagatc taatcctgtg   3600

ggaaaaaaga acaacagtgc tgcagggcta tgaaattgac gcgtccaagc ttggaggatg   3660

gagcctagac aaacatcatg ccctcaacat tcaaagtggc atcctgcaca aagggaatgg   3720

ggagaaccag tttgtgtctc agcagcctcc tgtcattggg agcatcatgg gcaatgggcg   3780

ccggagaagc atctcctgcc ccagctgcaa cggccttgct gacggcaaca agctcctggc   3840

cccagtggcc ctcacctgtg gctctgacgg gagcctctat gtgggtgatt tcaactacat   3900

tagaaggatc ttcccctctg gaaatgtcac caacatccta gagctgagaa ataaagattt   3960

cagacatagt cacagtccag cacacaaata ctacctggcc acagacccca tgagtggggc   4020

cgtcttcctt tctgacagca acagccggcg ggtctttaaa atcaagtcca ctgtggtggt   4080

gaaggacctt gtcaagaact ctgaggtggt tgcggggaca ggtgaccagt gcctcccctt   4140

tgatgacact cgctgcgggg atggtgggaa ggccacagaa gccacactca ccaatcccag   4200

gggcattaca gtggacaagt ttgggctgat ctacttcgtg gatggcacca tgatcagacg   4260

catcgatcag aatgggatca tctccaccct gctcggctct aatgatctca catcagcccg   4320

gccactcagc tgtgattctg tcatggatat ttcccaggtt cacctggagt ggcccacaga   4380

cttagccatc aacccaatgg acaactcact ttatgtcctc gacaacaatg tggtcctgca   4440

aatctctgaa aaccaccagg tgcgcattgt cgccgggagg cccatgcact gccaggtccc   4500

tggcattgac cacttcctgc taagcaaggt ggccatccac gcaaccctgg agtcagccac   4560

cgctttggct gtttcacaca atggggtcct gtatattgct gagactgatg agaaaaagat   4620

caaccgcatc aggcaggtca ccactagtgg agagatctca ctcgttgctg gggcccccag   4680

tggctgtgac tgtaaaaatg atgccaactg tgattgtttt tctggagacg atggttatgc   4740

caaggatgca aagttaaata ccccatcttc cttggctgtg tgtgctgatg gggagctcta   4800

cgtggccgac cttgggaaca tccgaattcg gtttatccgg aagaacaagc ctttcctcaa   4860

cacccagaac atgtatgagc tgtcttcacc aattgaccag gagctctatc tgtttgatac   4920

caccggcaag cacctgtaca cccaaagcct gcccacagga gactacctgt acaacttcac   4980

ctacactggg gacggcgaca tcacactcat cacagacaac aatggcaaca tggtaaatgt   5040

ccgccgagac tctactggga tgcccctctg gctggtggtc ccagatggcc aggtgtactg   5100

ggtgaccatg ggcaccaaca gtgcactcaa gagtgtgacc acacaaggac acgagttggc   5160

catgatgaca taccatggca attccggcct tctggcaacc aaaagcaatg aaaacggatg   5220

gacaacattt tatgagtacg acagctttgg ccgcctgaca aatgtgacct tccctactgg   5280

ccaggtgagc agtttccgaa gtgatacaga cagttcagtg catgtccagg tagagacctc   5340

cagcaaggat gatgtcacca taaccaccaa cctgtctgcc tcaggcgcct tctacacact   5400

gctgcaagac caagtccgga acagctacta catcggggcc gatggctcct tgcggctgct   5460

gctggccaac ggcatggagg tggcgctgca gactgagccc cacttgctgg ctggcaccgt   5520

caaccccacc gtgggcaaga ggaatgtcac gctgcccatc gacaacggcc tcaacctggt   5580

ggagtggcgc cagcgcaaag agcaggctcg gggccaggtc actgtctttg ggcgccggct   5640

gcgggttcac aaccgaaatc tcctatctct ggactttgat cgcgtaacac gcacagagaa   5700

gatctatgat gaccaccgca agttcaccct tcggattctg tacgaccagg cggggcggcc   5760

cagcctctgg tcacccagca gcaggctgaa tggtgtcaac gtgacatact cccctggggg   5820

ttacattgct ggcatccaga ggggcatcat gtctgaaaga atggaatacg accaggcggg   5880

ccgcatcaca tccaggatct tcgctgatgg gaagacatgg agctacacat acttagagaa   5940

gtccatggtg ctgctactac acagccagag gcagtatatc tttgagttcg acaagaatga   6000

ccgcctctct tctgtgacga tgcccaacgt ggcgcggcag acactagaga ccatccgctc   6060

agtgggctac tacagaaaca tctatcagcc ccctgagggc aatgcctcag tcatacagga   6120

cttcactgag gatgggcacc tccttcacac cttctacctg ggcactggcc gcagggtgat   6180

atacaagtat ggcaaactgt caaagctggc agagacgctc tatgacacca ccaaggtcag   6240

tttcacctat gacgagacgg caggcatgct gaagaccatc aacctacaga atgagggctt   6300

cacctgcacc atccgctacc gtcagattgg gcccctgatt gaccgacaga tcttccgctt   6360

cactgaggaa ggcatggtca acgcccgttt tgactacaac tatgacaaca gcttccgggt   6420

gaccagcatg caggctgtga tcaacgagac cccactgccc attgatctct atcgctatga   6480

tgatgtgtca ggcaagacag agcagtttgg gaagtttggt gtcatttact atgacattaa   6540

ccagatcatc accacagctg tcatgaccca caccaagcat tttgatgcat atggcaggat   6600

gaaggaagtg cagtatgaga tcttccgctc gctcatgtac tggatgaccg tccagtatga   6660

taacatgggg cgagtagtga agaaggagct gaaggtagga ccctacgcca ataccactcg   6720

ctactcctat gagtatgatg ctgacggcca gctgcagaca gtctccatca atgacaagcc   6780

actctggcgc tacagctacg acctcaatgg gaacctgcac ttactgagcc ctgggaacag   6840

tgcacggctc acaccactac ggtatgacat ccgcgaccgc atcactcggc tgggtgacgt   6900

gcaatacaag atggatgagg atggcttcct gaggcagcgg ggcggtgata tctttgagta   6960

caactcagct ggcctgctca tcaaggccta caaccgggct ggcagctgga gtgtcaggta   7020

ccgctacgat ggcctggggc ggcgcgtgtc cagcaagagc agccacagcc accacctgca   7080

gttcttctat gcagacctga ccaaccccac caaggtcacc cacctgtaca accactccag   7140

ctctgagatc acctccctct actacgactt gcaaggacac ctctttgcca tggagctgag   7200

cagtggtgat gagttttaca tagcttgtga caacatcggg acccctcttg ctgtctttag   7260

tggaacaggt ttgatgatca agcaaatcct gtacacagcc tatggggaga tctacatgga   7320

taccaacccc aactttcaga tcatcatagg ctaccatggt ggcctctatg atccactcac   7380

caagcttgtc cacatgggcc ggcgagatta tgatgtgctg gccggacgct ggactagccc   7440

agaccacgag ctgtggaagc accttagtag cagcaacgtc atgcctttta atctctatat   7500

gttcaaaaac aacaacccca tcagcaactc ccaggacatc aagtgcttca tgacagatgt   7560

taacagctgg ctgctcacct ttggattcca gctacacaac gtgatccctg gttatcccaa   7620

accagacatg gatgccatgg aaccctccta cgagctcatc cacacacaga tgaaaacgca   7680

ggagtgggac aacagcaagt ctatcctcgg ggtacagtgt gaagtacaga agcagctcaa   7740

ggcctttgtc accttagaac ggtttgacca gctctatggc tccacaatca ccagctgcca   7800

gcaggctcca aagaccaaga agtttgcatc cagcggctca gtctttggca agggggtcaa   7860

gtttgccttg aaggatggcc gagtgaccac agacatcatc agtgtggcca atgaggatgg   7920

gcgaagggtt gctgccatct tgaaccatgc ccactaccta gagaacctgc acttcaccat   7980

tgatggggtg gatacccatt actttgtgaa accaggacct tcagaaggtg acctggccat   8040

cctgggcctc agtggggggc ggcgaaccct ggagaatggg gtcaacgtca ctgtgtccca   8100

gatcaacaca gtacttaatg gcaggactag acgctacaca gacatccagc tccagtacgg   8160

ggcactgtgc ttgaacacac gctacgggac aacgttggat gaggagaagg cacgggtcct   8220

ggagctggcc cggcagagag ccgtgcgcca agcgtgggcc cgcgagcagc agagactgcg   8280

ggaaggggag gaaggcctgc gggcctggac agagggggag aagcagcagg tgctgagcac   8340

agggcgggtg caaggctacg acggcttttt cgtgatctct gtcgagcagt acccagaact   8400

gtcagacagc gccaacaaca tccacttcat gagacagagc gagatgggcc ggaggtgaca   8460

gagaggacca aggacttctt gccaaagaca gctactcttt tgtggccgca tacctgactg   8520

tgttgtactt ttaaaaaaat gattttttaa caagtgcaga aacaaaaaga tactggttgc   8580

attgtaactc atgcaacatc ctttttttta gaaaagaaaa acacagattt ggccttcgca   8640

cattttttgc aaagaacaga aggtattttt ttctgtagtg tgatcacaat gaaaacttta   8700

ttgtcttttg ttcccttttt ccttgaggat ttttcccttg tcgtttgggg tatgtatctc   8760

ctctctgaga tgcatctcct ggggtgtgtc ctcgtctgtc cctaggtacc cagtgtgatg   8820

tgggacatga atgtctgtgc taacttgtct catgtgcaac cctttcttct tcgactgggg   8880

tcgggcagga gtaaagggag tgatgggcca gtacaacacc ccttccaagg gggcctggga   8940

ggagggtctg taggacctga ggctccttgg cagggctcct gcagaagagt ggtggatttc   9000

ttctcacctt gttctctgcc tccagaggat catagatggc ttcatcttgc tccagggaat   9060

ttcatggtgt tgttcagcac cttttttaag ctgccccaaa ctcctgttca agctttctat   9120

tttgatgctg aatgaaaccc cctaccactt ttgcaaatcc tgtgtagttg tcggtgccac   9180

ccccatgctg ggatagagaa agtgtctccc aggtcctttc ccccagacca gtgacataac   9240

atcctgggct cagagtccca tcctcccggg agggaaagca cccaggatgc ctgtgattgg   9300

ttggtcctcc atgatgttcc tgttcatctc ctcctttctc ccaaagccag atgtgagaac   9360

gagcactgca cagcaagcct tcaatgtggg caccatgtcc acagaacaga aggccaccca   9420

tggcaaaggc atggcagtgg tggcgagggc accagcctgc cttccgaggc aaagccctct   9480

ctctatgact ttgagtatct tccctccacc actcagccgc caccactgag acgtaggaat   9540

gtggagggag gtgcttggtg gcctttgatt ctggaaaaat gcttaacaaa aaaagccagc   9600

caaagagagg aaggcataag ctaagcatcc ttctaaccag ttcccaaagt cccatctgcc   9660

tccatgtacc agctgatcgc agagctggac tggggcaggc tgggcttcca ggaaattcct   9720

gaagttctga aacagcttcc cctctagaga agcccaccca atgtgttttt tagtgacagg   9780

aagaaaggag ggaagagctg atgtggtgtg gcctgcccat atcatacaac cccaccagga   9840

gcagggcagt tcccaaggtg ggtgcccgta gatctgggag gccaggctgg catgattcct   9900

gtgaagaact gtgcctgtgt cgtcagggag aggcctgagc cctctcagaa gcagggacag   9960

cccacacctg aagagcacgc ccaagctgag gcagcagcca gcaggctggg ggagcagtga  10020

gggcaggggg agtcacagcc agagctggga gccccttgtt caaggattcc attcctggtt  10080

catccgccta attaccattg tcattaccac tcacaggagg ctctgggaga tgggagggga  10140

agccaaatgc ttccttttaa gctgggcttc ttagaaaatg gaacttttat gggttacatt  10200

tacattaagt gtggaaaatg aattctgagt ctgagctatt ccccgtggaa accttgttgg  10260

actgataagc tcatggcacc tctatagcct tactcacata gtcttcagaa tattacacaa  10320

gttaatgaaa ctgagaaggt ctgactgcat gaggatcgga gcagcatgta gtctgggttc  10380

tgcctggcag agggaggcaa ccaaaacttc ttggggagag gagatttcgc cttaacgtca  10440

tcccactggg attagaggat gtgtttcgct aagtgctctt cctgtttcca aaaaaaaagc  10500

caccctgctg cagcagtgcg ctttggcctg cttgtccact ggttgcccat tgcccctgga  10560

tccagagctc tactgagtca gatacagtgc tctgcaggcc tgctgtggga ggcatgagct  10620

ggagatgggg gctcccatct ggcaggatca ttcttggatg agatggaaaa cagtttggcc  10680

tgaagaacac aagttttgtc ctccagaagg gacttacgcc tctcaaaatg tactcttcat  10740

accaagggcc cttgggcaaa gtgctcctgc ccagttgatc agtcccatcc tggctgcctg  10800

acatcagtga agacctgctg gggatgtctg ctcagaggtc aggaacggca tgcggtccac  10860

aggaaccagc tccctacgct tcccccacgc cctgtccctc ctccacagcc ccctccccaa  10920

aggaataggg tggactttta gggatcaaaa acagaattat tgggtgtttc atttattttt  10980

ttctttctac tgagtgtttg tttctttaaa ggatcttata tttttcctgt gctacatacc  11040

accacagcag cccagcttct gtggggagag aagttgaagg atcccgaagc tttagaaaaa  11100

ggatctcagc tgtggcacag gcagtgttat gcgcctcact gccacattgg tgctgttgta  11160

ttgaaggtgg tgcttctggc cttggccctt ttgagttggt ttccatttgg gctgcaggtg  11220

actcagtgac tccctcctca agctgtcctc ctgctaagac cagcagtcac aaacccatgg  11280

caagggtgag tgtgaaggcc taaccctgtg cctatgtaat aggctccaag catcgactcc  11340

catcctgaga ggaccggccc ttttgacact caccaaccaa atctgttcat tcgatagagt  11400

gaccaggcct ccctcacctg cccaggtgta tgatcctaca gttcctgcct tctctcctac  11460

cccgcacagc tgccaactgg tcctacatcc tcagcccctc tgccaccacc ttaaatagga  11520

ctttactgat tccccaactt tgtttttttg taggatgaga tttccttttt atcccacccc  11580

cccacacccc aaacagacat tgctggaggg cagactggag gaaggggaag gcatgcaggt  11640

aaattactgc cttgtcagcc tctgaccctc atctctcaga attgttggct gagaattaac  11700

ccaaggacca caccagtgcc tgatttctac ttagggagag aggattggaa acgatcccta  11760

agaaactgac tgagggtgag aatggccagg aggtgtgtgt ccaaataacc aggagggggc  11820

acagaagatg atggcaaggc agactgggca gtgttttgta gacacagaac aaagaatcag  11880

aatttgaaaa aagaagaaaa acaaatcttc gcagctgcaa ctttaaagta tcacctttat  11940

agatggcagg gatttccatt atgcaaatgg aatctaagat ttcaatgtga aatcttagaa  12000

tgcagtttta ccacttgcag tcttgtattt gtggtggcca tgtggtgagg gcggtgatgc  12060

tgagctttct gcccaggagg aatgagcttt caagctctca gcagggtgtc aggcttgggg  12120

atttgagcat ccactgctca aagtccaggc tattctccag tcctcacggc agccactaag  12180

cccaggagcc agacctggcc cggggacaca tctcctgagg gatcccagaa agaacccagt  12240

ctttcctttc ccttggggtc cttgttagaa tgaaaacctc tctatttaag gcacatcatt  12300

cccagctagg tttatacact tgtctatatt ttactggagg aaagggaatt aaaaaagaac  12360

tctgcagttc aaggcccttt catttaacct tccaaaaaca gcaaactcat tttaaagact  12420

cattgctgag gtgatagaga gaaaccttat cctctccaac cttcacattc acaaaaacca  12480

tccttgtgta cttgactgcc ctagacagtg gtgactctta ggtttcatta cgaatgtgga  12540

atatcagagt gtgggaaggc ccaggcgagg gccaatgttg tgtttcttac cccctctgga  12600

atgccaaagg caaggtacta ggtgacctcc tggtccccaa gaaaatgtga tttattctga  12660

gggcgaacag ccaagggagg actagtctgg agcacgctcg gccgtcctgg caggagctga  12720

gcctcaggtg tctggcggtg ccccagcagc cctggattca cccaacacca gaatcccact  12780

tttctaaatc cacctgttgt tctgagcacc tctgaacccg cagcttcggc aaaaggagtc  12840

tgtaccaagc tgcttctgga tgaccaacac tggagactct ggccttacca tgtggaaatc  12900

attttcctga agtctggaac taattttgag aagttttttt ctcaacactt ttgtgtttct  12960

aacactgtat cttgactgtg taaataccaa caaggctgta aataaatgca gatgtagata  13020

ccttctagaa aaaaaaaagc ataaaaacaa aaccagaagt gatcccgtgt agccttcgtt  13080

gacaaataaa gactattttg tgtttacagg tgtctggtgg cctttgcttg gagataaagg  13140

cttcctcttg cctgtcccag cccccgagcc atcctgggtt tgcacttccc tgctggctgc  13200

tatcaggatg acctgggaga ggactcagtc ctaggcccca gggtccctct aaatccctcc  13260

aggctgcagc tctgtcaaga gggatgtcca gagggtctct aagaccctga agcttgactt  13320

tgcaattgca tgacaggaat aaatatcaca gctcctctga catcactagt gcagcgtggc  13380

tccccatccc actgctgccc tcgttcaggg acaggctgaa ggggccaacg aacccaaccc  13440

tcccagagga gggagccttg ctccaccact gggcacacag agtcatccac catgccactg  13500

ccttccacaa gggatgtgag ccgttgcact ttaaaaataa atgactgtat attcatc     13557


<210>  8025
<211>  2769
<212>  PRT
<213>  Homo sapiens

<400>  8025

Met Asp Val Lys Glu Arg Lys Pro Tyr Arg Ser Leu Thr Arg Arg Arg 
1               5                   10                  15


Asp Ala Glu Arg Arg Tyr Thr Ser Ser Ser Ala Asp Ser Glu Glu Gly 
            20                  25                  30


Lys Ala Pro Gln Lys Ser Tyr Ser Ser Ser Glu Thr Leu Lys Ala Tyr 
        35                  40                  45


Asp Gln Asp Ala Arg Leu Ala Tyr Gly Ser Arg Val Lys Asp Ile Val 
    50                  55                  60


Pro Gln Glu Ala Glu Glu Phe Cys Arg Thr Gly Ala Asn Phe Thr Leu 
65                  70                  75                  80


Arg Glu Leu Gly Leu Glu Glu Val Thr Pro Pro His Gly Thr Leu Tyr 
                85                  90                  95


Arg Thr Asp Ile Gly Leu Pro His Cys Gly Tyr Ser Met Gly Ala Gly 
            100                 105                 110


Ser Asp Ala Asp Met Glu Ala Asp Thr Val Leu Ser Pro Glu His Pro 
        115                 120                 125


Val Arg Leu Trp Gly Arg Ser Thr Arg Ser Gly Arg Ser Ser Cys Leu 
    130                 135                 140


Ser Ser Arg Ala Asn Ser Asn Leu Thr Leu Thr Asp Thr Glu His Glu 
145                 150                 155                 160


Asn Thr Glu Thr Asp His Pro Gly Gly Leu Gln Asn His Ala Arg Leu 
                165                 170                 175


Arg Thr Pro Pro Pro Pro Leu Ser His Ala His Thr Pro Asn Gln His 
            180                 185                 190


His Ala Ala Ser Ile Asn Ser Leu Asn Arg Gly Asn Phe Thr Pro Arg 
        195                 200                 205


Ser Asn Pro Ser Pro Ala Pro Thr Asp His Ser Leu Ser Gly Glu Pro 
    210                 215                 220


Pro Ala Gly Gly Ala Gln Glu Pro Ala His Ala Gln Glu Asn Trp Leu 
225                 230                 235                 240


Leu Asn Ser Asn Ile Pro Leu Glu Thr Arg Asn Leu Gly Lys Gln Pro 
                245                 250                 255


Phe Leu Gly Thr Leu Gln Asp Asn Leu Ile Glu Met Asp Ile Leu Gly 
            260                 265                 270


Ala Ser Arg His Asp Gly Ala Tyr Ser Asp Gly His Phe Leu Phe Lys 
        275                 280                 285


Pro Gly Gly Thr Ser Pro Leu Phe Cys Thr Thr Ser Pro Gly Tyr Pro 
    290                 295                 300


Leu Thr Ser Ser Thr Val Tyr Ser Pro Pro Pro Arg Pro Leu Pro Arg 
305                 310                 315                 320


Ser Thr Phe Ala Arg Pro Ala Phe Asn Leu Lys Lys Pro Ser Lys Tyr 
                325                 330                 335


Cys Asn Trp Lys Cys Ala Ala Leu Ser Ala Ile Val Ile Ser Ala Thr 
            340                 345                 350


Leu Val Ile Leu Leu Ala Tyr Phe Val Ala Met His Leu Phe Gly Leu 
        355                 360                 365


Asn Trp His Leu Gln Pro Met Glu Gly Gln Met Tyr Glu Ile Thr Glu 
    370                 375                 380


Asp Thr Ala Ser Ser Trp Pro Val Pro Thr Asp Val Ser Leu Tyr Pro 
385                 390                 395                 400


Ser Gly Gly Thr Gly Leu Glu Thr Pro Asp Arg Lys Gly Lys Gly Thr 
                405                 410                 415


Thr Glu Gly Lys Pro Ser Ser Phe Phe Pro Glu Asp Ser Phe Ile Asp 
            420                 425                 430


Ser Gly Glu Ile Asp Val Gly Arg Arg Ala Ser Gln Lys Ile Pro Pro 
        435                 440                 445


Gly Thr Phe Trp Arg Ser Gln Val Phe Ile Asp His Pro Val His Leu 
    450                 455                 460


Lys Phe Asn Val Ser Leu Gly Lys Ala Ala Leu Val Gly Ile Tyr Gly 
465                 470                 475                 480


Arg Lys Gly Leu Pro Pro Ser His Thr Gln Phe Asp Phe Val Glu Leu 
                485                 490                 495


Leu Asp Gly Arg Arg Leu Leu Thr Gln Glu Ala Arg Ser Leu Glu Gly 
            500                 505                 510


Thr Pro Arg Gln Ser Arg Gly Thr Val Pro Pro Ser Ser His Glu Thr 
        515                 520                 525


Gly Phe Ile Gln Tyr Leu Asp Ser Gly Ile Trp His Leu Ala Phe Tyr 
    530                 535                 540


Asn Asp Gly Lys Glu Ser Glu Val Val Ser Phe Leu Thr Thr Ala Ile 
545                 550                 555                 560


Glu Ser Val Asp Asn Cys Pro Ser Asn Cys Tyr Gly Asn Gly Asp Cys 
                565                 570                 575


Ile Ser Gly Thr Cys His Cys Phe Leu Gly Phe Leu Gly Pro Asp Cys 
            580                 585                 590


Gly Arg Ala Ser Cys Pro Val Leu Cys Ser Gly Asn Gly Gln Tyr Met 
        595                 600                 605


Lys Gly Arg Cys Leu Cys His Ser Gly Trp Lys Gly Ala Glu Cys Asp 
    610                 615                 620


Val Pro Thr Asn Gln Cys Ile Asp Val Ala Cys Ser Asn His Gly Thr 
625                 630                 635                 640


Cys Ile Thr Gly Thr Cys Ile Cys Asn Pro Gly Tyr Lys Gly Glu Ser 
                645                 650                 655


Cys Glu Glu Val Asp Cys Met Asp Pro Thr Cys Ser Gly Arg Gly Val 
            660                 665                 670


Cys Val Arg Gly Glu Cys His Cys Ser Val Gly Trp Gly Gly Thr Asn 
        675                 680                 685


Cys Glu Thr Pro Arg Ala Thr Cys Leu Asp Gln Cys Ser Gly His Gly 
    690                 695                 700


Thr Phe Leu Pro Asp Thr Gly Leu Cys Ser Cys Asp Pro Ser Trp Thr 
705                 710                 715                 720


Gly His Asp Cys Ser Ile Glu Ile Cys Ala Ala Asp Cys Gly Gly His 
                725                 730                 735


Gly Val Cys Val Gly Gly Thr Cys Arg Cys Glu Asp Gly Trp Met Gly 
            740                 745                 750


Ala Ala Cys Asp Gln Arg Ala Cys His Pro Arg Cys Ala Glu His Gly 
        755                 760                 765


Thr Cys Arg Asp Gly Lys Cys Glu Cys Ser Pro Gly Trp Asn Gly Glu 
    770                 775                 780


His Cys Thr Ile Ala His Tyr Leu Asp Arg Val Val Lys Glu Gly Cys 
785                 790                 795                 800


Pro Gly Leu Cys Asn Gly Asn Gly Arg Cys Thr Leu Asp Leu Asn Gly 
                805                 810                 815


Trp His Cys Val Cys Gln Leu Gly Trp Arg Gly Ala Gly Cys Asp Thr 
            820                 825                 830


Ser Met Glu Thr Ala Cys Gly Asp Ser Lys Asp Asn Asp Gly Asp Gly 
        835                 840                 845


Leu Val Asp Cys Met Asp Pro Asp Cys Cys Leu Gln Pro Leu Cys His 
    850                 855                 860


Ile Asn Pro Leu Cys Leu Gly Ser Pro Asn Pro Leu Asp Ile Ile Gln 
865                 870                 875                 880


Glu Thr Gln Val Pro Val Ser Gln Gln Asn Leu His Ser Phe Tyr Asp 
                885                 890                 895


Arg Ile Lys Phe Leu Val Gly Arg Asp Ser Thr His Ile Ile Pro Gly 
            900                 905                 910


Glu Asn Pro Phe Asp Gly Gly His Ala Cys Val Ile Arg Gly Gln Val 
        915                 920                 925


Met Thr Ser Asp Gly Thr Pro Leu Val Gly Val Asn Ile Ser Phe Val 
    930                 935                 940


Asn Asn Pro Leu Phe Gly Tyr Thr Ile Ser Arg Gln Asp Gly Ser Phe 
945                 950                 955                 960


Asp Leu Val Thr Asn Gly Gly Ile Ser Ile Ile Leu Arg Phe Glu Arg 
                965                 970                 975


Ala Pro Phe Ile Thr Gln Glu His Thr Leu Trp Leu Pro Trp Asp Arg 
            980                 985                 990


Phe Phe Val Met Glu Thr Ile Ile Met Arg His Glu Glu Asn Glu Ile 
        995                 1000                1005


Pro Ser Cys Asp Leu Ser Asn Phe Ala Arg Pro Asn Pro Val Val Ser 
    1010                1015                1020


Pro Ser Pro Leu Thr Ser Phe Ala Ser Ser Cys Ala Glu Lys Gly Pro 
1025                1030                1035                1040


Ile Val Pro Glu Ile Gln Ala Leu Gln Glu Glu Ile Ser Ile Ser Gly 
                1045                1050                1055


Cys Lys Met Arg Leu Ser Tyr Leu Ser Ser Arg Thr Pro Gly Tyr Lys 
            1060                1065                1070


Ser Val Leu Arg Ile Ser Leu Thr His Pro Thr Ile Pro Phe Asn Leu 
        1075                1080                1085


Met Lys Val His Leu Met Val Ala Val Glu Gly Arg Leu Phe Arg Lys 
    1090                1095                1100


Trp Phe Ala Ala Ala Pro Asp Leu Ser Tyr Tyr Phe Ile Trp Asp Lys 
1105                1110                1115                1120


Thr Asp Val Tyr Asn Gln Lys Val Phe Gly Leu Ser Glu Ala Phe Val 
                1125                1130                1135


Ser Val Gly Tyr Glu Tyr Glu Ser Cys Pro Asp Leu Ile Leu Trp Glu 
            1140                1145                1150


Lys Arg Thr Thr Val Leu Gln Gly Tyr Glu Ile Asp Ala Ser Lys Leu 
        1155                1160                1165


Gly Gly Trp Ser Leu Asp Lys His His Ala Leu Asn Ile Gln Ser Gly 
    1170                1175                1180


Ile Leu His Lys Gly Asn Gly Glu Asn Gln Phe Val Ser Gln Gln Pro 
1185                1190                1195                1200


Pro Val Ile Gly Ser Ile Met Gly Asn Gly Arg Arg Arg Ser Ile Ser 
                1205                1210                1215


Cys Pro Ser Cys Asn Gly Leu Ala Asp Gly Asn Lys Leu Leu Ala Pro 
            1220                1225                1230


Val Ala Leu Thr Cys Gly Ser Asp Gly Ser Leu Tyr Val Gly Asp Phe 
        1235                1240                1245


Asn Tyr Ile Arg Arg Ile Phe Pro Ser Gly Asn Val Thr Asn Ile Leu 
    1250                1255                1260


Glu Leu Arg Asn Lys Asp Phe Arg His Ser His Ser Pro Ala His Lys 
1265                1270                1275                1280


Tyr Tyr Leu Ala Thr Asp Pro Met Ser Gly Ala Val Phe Leu Ser Asp 
                1285                1290                1295


Ser Asn Ser Arg Arg Val Phe Lys Ile Lys Ser Thr Val Val Val Lys 
            1300                1305                1310


Asp Leu Val Lys Asn Ser Glu Val Val Ala Gly Thr Gly Asp Gln Cys 
        1315                1320                1325


Leu Pro Phe Asp Asp Thr Arg Cys Gly Asp Gly Gly Lys Ala Thr Glu 
    1330                1335                1340


Ala Thr Leu Thr Asn Pro Arg Gly Ile Thr Val Asp Lys Phe Gly Leu 
1345                1350                1355                1360


Ile Tyr Phe Val Asp Gly Thr Met Ile Arg Arg Ile Asp Gln Asn Gly 
                1365                1370                1375


Ile Ile Ser Thr Leu Leu Gly Ser Asn Asp Leu Thr Ser Ala Arg Pro 
            1380                1385                1390


Leu Ser Cys Asp Ser Val Met Asp Ile Ser Gln Val His Leu Glu Trp 
        1395                1400                1405


Pro Thr Asp Leu Ala Ile Asn Pro Met Asp Asn Ser Leu Tyr Val Leu 
    1410                1415                1420


Asp Asn Asn Val Val Leu Gln Ile Ser Glu Asn His Gln Val Arg Ile 
1425                1430                1435                1440


Val Ala Gly Arg Pro Met His Cys Gln Val Pro Gly Ile Asp His Phe 
                1445                1450                1455


Leu Leu Ser Lys Val Ala Ile His Ala Thr Leu Glu Ser Ala Thr Ala 
            1460                1465                1470


Leu Ala Val Ser His Asn Gly Val Leu Tyr Ile Ala Glu Thr Asp Glu 
        1475                1480                1485


Lys Lys Ile Asn Arg Ile Arg Gln Val Thr Thr Ser Gly Glu Ile Ser 
    1490                1495                1500


Leu Val Ala Gly Ala Pro Ser Gly Cys Asp Cys Lys Asn Asp Ala Asn 
1505                1510                1515                1520


Cys Asp Cys Phe Ser Gly Asp Asp Gly Tyr Ala Lys Asp Ala Lys Leu 
                1525                1530                1535


Asn Thr Pro Ser Ser Leu Ala Val Cys Ala Asp Gly Glu Leu Tyr Val 
            1540                1545                1550


Ala Asp Leu Gly Asn Ile Arg Ile Arg Phe Ile Arg Lys Asn Lys Pro 
        1555                1560                1565


Phe Leu Asn Thr Gln Asn Met Tyr Glu Leu Ser Ser Pro Ile Asp Gln 
    1570                1575                1580


Glu Leu Tyr Leu Phe Asp Thr Thr Gly Lys His Leu Tyr Thr Gln Ser 
1585                1590                1595                1600


Leu Pro Thr Gly Asp Tyr Leu Tyr Asn Phe Thr Tyr Thr Gly Asp Gly 
                1605                1610                1615


Asp Ile Thr Leu Ile Thr Asp Asn Asn Gly Asn Met Val Asn Val Arg 
            1620                1625                1630


Arg Asp Ser Thr Gly Met Pro Leu Trp Leu Val Val Pro Asp Gly Gln 
        1635                1640                1645


Val Tyr Trp Val Thr Met Gly Thr Asn Ser Ala Leu Lys Ser Val Thr 
    1650                1655                1660


Thr Gln Gly His Glu Leu Ala Met Met Thr Tyr His Gly Asn Ser Gly 
1665                1670                1675                1680


Leu Leu Ala Thr Lys Ser Asn Glu Asn Gly Trp Thr Thr Phe Tyr Glu 
                1685                1690                1695


Tyr Asp Ser Phe Gly Arg Leu Thr Asn Val Thr Phe Pro Thr Gly Gln 
            1700                1705                1710


Val Ser Ser Phe Arg Ser Asp Thr Asp Ser Ser Val His Val Gln Val 
        1715                1720                1725


Glu Thr Ser Ser Lys Asp Asp Val Thr Ile Thr Thr Asn Leu Ser Ala 
    1730                1735                1740


Ser Gly Ala Phe Tyr Thr Leu Leu Gln Asp Gln Val Arg Asn Ser Tyr 
1745                1750                1755                1760


Tyr Ile Gly Ala Asp Gly Ser Leu Arg Leu Leu Leu Ala Asn Gly Met 
                1765                1770                1775


Glu Val Ala Leu Gln Thr Glu Pro His Leu Leu Ala Gly Thr Val Asn 
            1780                1785                1790


Pro Thr Val Gly Lys Arg Asn Val Thr Leu Pro Ile Asp Asn Gly Leu 
        1795                1800                1805


Asn Leu Val Glu Trp Arg Gln Arg Lys Glu Gln Ala Arg Gly Gln Val 
    1810                1815                1820


Thr Val Phe Gly Arg Arg Leu Arg Val His Asn Arg Asn Leu Leu Ser 
1825                1830                1835                1840


Leu Asp Phe Asp Arg Val Thr Arg Thr Glu Lys Ile Tyr Asp Asp His 
                1845                1850                1855


Arg Lys Phe Thr Leu Arg Ile Leu Tyr Asp Gln Ala Gly Arg Pro Ser 
            1860                1865                1870


Leu Trp Ser Pro Ser Ser Arg Leu Asn Gly Val Asn Val Thr Tyr Ser 
        1875                1880                1885


Pro Gly Gly Tyr Ile Ala Gly Ile Gln Arg Gly Ile Met Ser Glu Arg 
    1890                1895                1900


Met Glu Tyr Asp Gln Ala Gly Arg Ile Thr Ser Arg Ile Phe Ala Asp 
1905                1910                1915                1920


Gly Lys Thr Trp Ser Tyr Thr Tyr Leu Glu Lys Ser Met Val Leu Leu 
                1925                1930                1935


Leu His Ser Gln Arg Gln Tyr Ile Phe Glu Phe Asp Lys Asn Asp Arg 
            1940                1945                1950


Leu Ser Ser Val Thr Met Pro Asn Val Ala Arg Gln Thr Leu Glu Thr 
        1955                1960                1965


Ile Arg Ser Val Gly Tyr Tyr Arg Asn Ile Tyr Gln Pro Pro Glu Gly 
    1970                1975                1980


Asn Ala Ser Val Ile Gln Asp Phe Thr Glu Asp Gly His Leu Leu His 
1985                1990                1995                2000


Thr Phe Tyr Leu Gly Thr Gly Arg Arg Val Ile Tyr Lys Tyr Gly Lys 
                2005                2010                2015


Leu Ser Lys Leu Ala Glu Thr Leu Tyr Asp Thr Thr Lys Val Ser Phe 
            2020                2025                2030


Thr Tyr Asp Glu Thr Ala Gly Met Leu Lys Thr Ile Asn Leu Gln Asn 
        2035                2040                2045


Glu Gly Phe Thr Cys Thr Ile Arg Tyr Arg Gln Ile Gly Pro Leu Ile 
    2050                2055                2060


Asp Arg Gln Ile Phe Arg Phe Thr Glu Glu Gly Met Val Asn Ala Arg 
2065                2070                2075                2080


Phe Asp Tyr Asn Tyr Asp Asn Ser Phe Arg Val Thr Ser Met Gln Ala 
                2085                2090                2095


Val Ile Asn Glu Thr Pro Leu Pro Ile Asp Leu Tyr Arg Tyr Asp Asp 
            2100                2105                2110


Val Ser Gly Lys Thr Glu Gln Phe Gly Lys Phe Gly Val Ile Tyr Tyr 
        2115                2120                2125


Asp Ile Asn Gln Ile Ile Thr Thr Ala Val Met Thr His Thr Lys His 
    2130                2135                2140


Phe Asp Ala Tyr Gly Arg Met Lys Glu Val Gln Tyr Glu Ile Phe Arg 
2145                2150                2155                2160


Ser Leu Met Tyr Trp Met Thr Val Gln Tyr Asp Asn Met Gly Arg Val 
                2165                2170                2175


Val Lys Lys Glu Leu Lys Val Gly Pro Tyr Ala Asn Thr Thr Arg Tyr 
            2180                2185                2190


Ser Tyr Glu Tyr Asp Ala Asp Gly Gln Leu Gln Thr Val Ser Ile Asn 
        2195                2200                2205


Asp Lys Pro Leu Trp Arg Tyr Ser Tyr Asp Leu Asn Gly Asn Leu His 
    2210                2215                2220


Leu Leu Ser Pro Gly Asn Ser Ala Arg Leu Thr Pro Leu Arg Tyr Asp 
2225                2230                2235                2240


Ile Arg Asp Arg Ile Thr Arg Leu Gly Asp Val Gln Tyr Lys Met Asp 
                2245                2250                2255


Glu Asp Gly Phe Leu Arg Gln Arg Gly Gly Asp Ile Phe Glu Tyr Asn 
            2260                2265                2270


Ser Ala Gly Leu Leu Ile Lys Ala Tyr Asn Arg Ala Gly Ser Trp Ser 
        2275                2280                2285


Val Arg Tyr Arg Tyr Asp Gly Leu Gly Arg Arg Val Ser Ser Lys Ser 
    2290                2295                2300


Ser His Ser His His Leu Gln Phe Phe Tyr Ala Asp Leu Thr Asn Pro 
2305                2310                2315                2320


Thr Lys Val Thr His Leu Tyr Asn His Ser Ser Ser Glu Ile Thr Ser 
                2325                2330                2335


Leu Tyr Tyr Asp Leu Gln Gly His Leu Phe Ala Met Glu Leu Ser Ser 
            2340                2345                2350


Gly Asp Glu Phe Tyr Ile Ala Cys Asp Asn Ile Gly Thr Pro Leu Ala 
        2355                2360                2365


Val Phe Ser Gly Thr Gly Leu Met Ile Lys Gln Ile Leu Tyr Thr Ala 
    2370                2375                2380


Tyr Gly Glu Ile Tyr Met Asp Thr Asn Pro Asn Phe Gln Ile Ile Ile 
2385                2390                2395                2400


Gly Tyr His Gly Gly Leu Tyr Asp Pro Leu Thr Lys Leu Val His Met 
                2405                2410                2415


Gly Arg Arg Asp Tyr Asp Val Leu Ala Gly Arg Trp Thr Ser Pro Asp 
            2420                2425                2430


His Glu Leu Trp Lys His Leu Ser Ser Ser Asn Val Met Pro Phe Asn 
        2435                2440                2445


Leu Tyr Met Phe Lys Asn Asn Asn Pro Ile Ser Asn Ser Gln Asp Ile 
    2450                2455                2460


Lys Cys Phe Met Thr Asp Val Asn Ser Trp Leu Leu Thr Phe Gly Phe 
2465                2470                2475                2480


Gln Leu His Asn Val Ile Pro Gly Tyr Pro Lys Pro Asp Met Asp Ala 
                2485                2490                2495


Met Glu Pro Ser Tyr Glu Leu Ile His Thr Gln Met Lys Thr Gln Glu 
            2500                2505                2510


Trp Asp Asn Ser Lys Ser Ile Leu Gly Val Gln Cys Glu Val Gln Lys 
        2515                2520                2525


Gln Leu Lys Ala Phe Val Thr Leu Glu Arg Phe Asp Gln Leu Tyr Gly 
    2530                2535                2540


Ser Thr Ile Thr Ser Cys Gln Gln Ala Pro Lys Thr Lys Lys Phe Ala 
2545                2550                2555                2560


Ser Ser Gly Ser Val Phe Gly Lys Gly Val Lys Phe Ala Leu Lys Asp 
                2565                2570                2575


Gly Arg Val Thr Thr Asp Ile Ile Ser Val Ala Asn Glu Asp Gly Arg 
            2580                2585                2590


Arg Val Ala Ala Ile Leu Asn His Ala His Tyr Leu Glu Asn Leu His 
        2595                2600                2605


Phe Thr Ile Asp Gly Val Asp Thr His Tyr Phe Val Lys Pro Gly Pro 
    2610                2615                2620


Ser Glu Gly Asp Leu Ala Ile Leu Gly Leu Ser Gly Gly Arg Arg Thr 
2625                2630                2635                2640


Leu Glu Asn Gly Val Asn Val Thr Val Ser Gln Ile Asn Thr Val Leu 
                2645                2650                2655


Asn Gly Arg Thr Arg Arg Tyr Thr Asp Ile Gln Leu Gln Tyr Gly Ala 
            2660                2665                2670


Leu Cys Leu Asn Thr Arg Tyr Gly Thr Thr Leu Asp Glu Glu Lys Ala 
        2675                2680                2685


Arg Val Leu Glu Leu Ala Arg Gln Arg Ala Val Arg Gln Ala Trp Ala 
    2690                2695                2700


Arg Glu Gln Gln Arg Leu Arg Glu Gly Glu Glu Gly Leu Arg Ala Trp 
2705                2710                2715                2720


Thr Glu Gly Glu Lys Gln Gln Val Leu Ser Thr Gly Arg Val Gln Gly 
                2725                2730                2735


Tyr Asp Gly Phe Phe Val Ile Ser Val Glu Gln Tyr Pro Glu Leu Ser 
            2740                2745                2750


Asp Ser Ala Asn Asn Ile His Phe Met Arg Gln Ser Glu Met Gly Arg 
        2755                2760                2765


Arg 



<210>  8026
<211>  3361
<212>  DNA
<213>  Homo sapiens

<400>  8026
atggttggtt gcatcggttc tcacgtccgc ccgcagaagg tgacggttct ttgcactacg     60

tcctccctag cacctgacgc tgccagacgt ttcaactttg gacttttcga ctcaacttat    120

ggtgagtgtg gtattatccg ctgtggtttt aattggcctt cttctgatta ttaatgaatt    180

aaagcatcat ttcaataaac agatatttat tggccattta gatttctcgt gtgtttgtga    240

aatacctttc catttaccca ttatttaatt gggttccttt tcttcttgat ttgtagcagt    300

tcctcgcgta ttttagtagt tttatttgtg gcaaagatct cctcccccgg gtggcctctg    360

ccctccggcg ctgggaagtc cgggcggcga ggcagcctct cccggggcgt tcgggctcct    420

ccggctctgc cccgatgtcg ttattacggc cgtttgcagc ctccgtgcca gggccggggg    480

tgcggttcgg gacgcgggat cctaggtcgg gtcctgcccc gcccatgtgg cgccggcgtc    540

tgtgttgtct gcggtctcca gggcagcgcc ggggcgggcg ggggcccggg cggcggcggc    600

ggcggcgcgg gaggatgcgg ggcccgtccg ggtcgcggcc gcggaggagc gccgggcagg    660

taacgctttt gtgaaccaca actttaaata tcagccagct gctcctatca acacgagtat    720

cccctgttaa ttttttgcat ttttcaagat gagtaaacgt aaactaattc ccaagctctc    780

tattcaatct cctgtccttc ataccaactt aaatgtccag tccacacacc cacctttgaa    840

gaaagaagac ttacatcgga tttcaaaaga ctccttggaa tctgattcag aaagcctcac    900

gcaagagatt atgtgccatt ctgagtttga tgatcgaatc cggggcaacg gtatggagcc    960

cgacagctta gacgaggagg aaagccctcg atggggaagc ctgcacgaga tggaagagga   1020

agcaagtgga aaagcagctc agatggctcg cgagcaaaac caccatacct gggaccaggg   1080

cgccaataac aggcaacaac caatagaaga caaatattca gacctccgct atgacccgaa   1140

ctggaagagt aagaaggagg aagggcagct gctgtctgtg gaagcgttgc cggagtccac   1200

ggacagctct ttagaaaatc tgcctttggc tcccctctac ccttcccagg agacgtcaat   1260

ggaactctcc gggggaaaag gcgagcagaa agagagtcca cagagtgcag cttctttact   1320

tggtagtgaa tttttaagcc caaactatga gcatggtgcc cgtcgcagca agccgttttc   1380

agagctgagc gacagtgacc tggaggagaa gtcgagcagc ctttctccgt acgtgaagag   1440

ctcaagttca cataacgagg ttttcctgcc gggatcacgt ggccctcggc gaaggaaatc   1500

caaacaacat tttgtggaaa aaaacaagct cactttggga ttacccaccc cgaaaacgga   1560

ctcttatctt caacttcaca ataaaaaaag aggggaatct catccagaac agatctccta   1620

ccccgtcaga gtaacagaca agacgtctat tcagaatgcc aaggaaatgg aaaatgctgc   1680

catcgatcct gaagataaat ggcatcaaag agcacaacag ctaaagaatt accaggaaca   1740

ctggtctcaa tatgaaagta caaaatcaag caatgtacca agagggcaac cttctgacat   1800

ggtgaatgac catcaacctt ccagaagacc agccaagctc aagattcgaa agcagtgtaa   1860

acaccagaat ggcctgaagt cttccacaac ggaagaggtg actgccagtc aggggaacca   1920

gaataaccct cccaggcagc aacaaaacca aaataagcct cttgatactt caacaaagcc   1980

tgaatcgatt gtgattatgc atgcctctaa caatgatgta caagcctcaa gggcacttag   2040

aagccacaat ctcaaagaaa cctccaatac atttgctcca ccaaaacagg cttttgacaa   2100

ggtcttatct aaaaactcta ctggatgtga ctctgggctg aatgttaata aagaaagagg   2160

acacaaagac caagaagaga aaagattttc atatcagcag ctacacaccc tttctgacat   2220

ggatttgaac aaccttaatg aactttctaa gagacacgtg ctcctgagcc agaaaggctc   2280

tcagtttgtt tatcacataa atactcatgg atcaaccaaa aataagaaac aactcaaaca   2340

gccttataca gagacaaaat acaggaactt agaaatgtta tggaaattcc attcttcttc   2400

tgacagccag acggttagag cttctccaga ttcatggctc acccagataa tggagcagca   2460

tcagcaagcc ttggtgcagc tgaccgacgt gcagcccagt gaaggggcct tatccagcgt   2520

cacgcttcca cctatactgt caagggtaga aagtgaatcc caactcagtt cagagagaag   2580

ccaaagaaac caagtgaaaa ttagccgtag caattctgaa ggctatctgt ttcaactgga   2640

aaagggaaaa aagcataaga aaagaagcag cagtaagaac accaagctga aaggttatca   2700

gaaaagagac gtgaagcttg gaggcctcgg acctgacttt gagtccatca gagacaaaac   2760

gcaaaaatta atacagcaaa aggaatatgc aaaacaagtc aaggagtaca acatgaagac   2820

actatccatt ctatcaaaac cacaaacaga aaaaactcaa aagaaatctg ctatccctcg   2880

gcagaaggct ttggaatacg ctaagaccat ccccaaaccc aaaccatcaa atctgactca   2940

tcaagcatca aaggaacaaa aaaatccaac ctatgctggg aaagaagaaa gtttacctga   3000

aatctcactg ctggaaatac tgcagaacag acacgaaagg gaaaaacagg ctgtggctgc   3060

tttcaaagtc cttcacatcg tatagacaac atttgatagg aaggagacca aaaatggtcc   3120

aggaatgaac gtggagaaaa gaaacgccaa ccaccttctc tgcgttgaga gtaatggcct   3180

attattatca tctatctgcc gtccatgttt gctttctgca ggatttaaaa tatgaggccc   3240

aattggatta tggtgccata ttttactttc taggaagaaa attttttaaa ttatttattt   3300

tcaaatcagt tagaattgga gctgaataat aactagagaa taaagctttt gttttatatt   3360

g                                                                   3361


<210>  8027
<211>  778
<212>  PRT
<213>  Homo sapiens

<400>  8027

Met Ser Lys Arg Lys Leu Ile Pro Lys Leu Ser Ile Gln Ser Pro Val 
1               5                   10                  15


Leu His Thr Asn Leu Asn Val Gln Ser Thr His Pro Pro Leu Lys Lys 
            20                  25                  30


Glu Asp Leu His Arg Ile Ser Lys Asp Ser Leu Glu Ser Asp Ser Glu 
        35                  40                  45


Ser Leu Thr Gln Glu Ile Met Cys His Ser Glu Phe Asp Asp Arg Ile 
    50                  55                  60


Arg Gly Asn Gly Met Glu Pro Asp Ser Leu Asp Glu Glu Glu Ser Pro 
65                  70                  75                  80


Arg Trp Gly Ser Leu His Glu Met Glu Glu Glu Ala Ser Gly Lys Ala 
                85                  90                  95


Ala Gln Met Ala Arg Glu Gln Asn His His Thr Trp Asp Gln Gly Ala 
            100                 105                 110


Asn Asn Arg Gln Gln Pro Ile Glu Asp Lys Tyr Ser Asp Leu Arg Tyr 
        115                 120                 125


Asp Pro Asn Trp Lys Ser Lys Lys Glu Glu Gly Gln Leu Leu Ser Val 
    130                 135                 140


Glu Ala Leu Pro Glu Ser Thr Asp Ser Ser Leu Glu Asn Leu Pro Leu 
145                 150                 155                 160


Ala Pro Leu Tyr Pro Ser Gln Glu Thr Ser Met Glu Leu Ser Gly Gly 
                165                 170                 175


Lys Gly Glu Gln Lys Glu Ser Pro Gln Ser Ala Ala Ser Leu Leu Gly 
            180                 185                 190


Ser Glu Phe Leu Ser Pro Asn Tyr Glu His Gly Ala Arg Arg Ser Lys 
        195                 200                 205


Pro Phe Ser Glu Leu Ser Asp Ser Asp Leu Glu Glu Lys Ser Ser Ser 
    210                 215                 220


Leu Ser Pro Tyr Val Lys Ser Ser Ser Ser His Asn Glu Val Phe Leu 
225                 230                 235                 240


Pro Gly Ser Arg Gly Pro Arg Arg Arg Lys Ser Lys Gln His Phe Val 
                245                 250                 255


Glu Lys Asn Lys Leu Thr Leu Gly Leu Pro Thr Pro Lys Thr Asp Ser 
            260                 265                 270


Tyr Leu Gln Leu His Asn Lys Lys Arg Gly Glu Ser His Pro Glu Gln 
        275                 280                 285


Ile Ser Tyr Pro Val Arg Val Thr Asp Lys Thr Ser Ile Gln Asn Ala 
    290                 295                 300


Lys Glu Met Glu Asn Ala Ala Ile Asp Pro Glu Asp Lys Trp His Gln 
305                 310                 315                 320


Arg Ala Gln Gln Leu Lys Asn Tyr Gln Glu His Trp Ser Gln Tyr Glu 
                325                 330                 335


Ser Thr Lys Ser Ser Asn Val Pro Arg Gly Gln Pro Ser Asp Met Val 
            340                 345                 350


Asn Asp His Gln Pro Ser Arg Arg Pro Ala Lys Leu Lys Ile Arg Lys 
        355                 360                 365


Gln Cys Lys His Gln Asn Gly Leu Lys Ser Ser Thr Thr Glu Glu Val 
    370                 375                 380


Thr Ala Ser Gln Gly Asn Gln Asn Asn Pro Pro Arg Gln Gln Gln Asn 
385                 390                 395                 400


Gln Asn Lys Pro Leu Asp Thr Ser Thr Lys Pro Glu Ser Ile Val Ile 
                405                 410                 415


Met His Ala Ser Asn Asn Asp Val Gln Ala Ser Arg Ala Leu Arg Ser 
            420                 425                 430


His Asn Leu Lys Glu Thr Ser Asn Thr Phe Ala Pro Pro Lys Gln Ala 
        435                 440                 445


Phe Asp Lys Val Leu Ser Lys Asn Ser Thr Gly Cys Asp Ser Gly Leu 
    450                 455                 460


Asn Val Asn Lys Glu Arg Gly His Lys Asp Gln Glu Glu Lys Arg Phe 
465                 470                 475                 480


Ser Tyr Gln Gln Leu His Thr Leu Ser Asp Met Asp Leu Asn Asn Leu 
                485                 490                 495


Asn Glu Leu Ser Lys Arg His Val Leu Leu Ser Gln Lys Gly Ser Gln 
            500                 505                 510


Phe Val Tyr His Ile Asn Thr His Gly Ser Thr Lys Asn Lys Lys Gln 
        515                 520                 525


Leu Lys Gln Pro Tyr Thr Glu Thr Lys Tyr Arg Asn Leu Glu Met Leu 
    530                 535                 540


Trp Lys Phe His Ser Ser Ser Asp Ser Gln Thr Val Arg Ala Ser Pro 
545                 550                 555                 560


Asp Ser Trp Leu Thr Gln Ile Met Glu Gln His Gln Gln Ala Leu Val 
                565                 570                 575


Gln Leu Thr Asp Val Gln Pro Ser Glu Gly Ala Leu Ser Ser Val Thr 
            580                 585                 590


Leu Pro Pro Ile Leu Ser Arg Val Glu Ser Glu Ser Gln Leu Ser Ser 
        595                 600                 605


Glu Arg Ser Gln Arg Asn Gln Val Lys Ile Ser Arg Ser Asn Ser Glu 
    610                 615                 620


Gly Tyr Leu Phe Gln Leu Glu Lys Gly Lys Lys His Lys Lys Arg Ser 
625                 630                 635                 640


Ser Ser Lys Asn Thr Lys Leu Lys Gly Tyr Gln Lys Arg Asp Val Lys 
                645                 650                 655


Leu Gly Gly Leu Gly Pro Asp Phe Glu Ser Ile Arg Asp Lys Thr Gln 
            660                 665                 670


Lys Leu Ile Gln Gln Lys Glu Tyr Ala Lys Gln Val Lys Glu Tyr Asn 
        675                 680                 685


Met Lys Thr Leu Ser Ile Leu Ser Lys Pro Gln Thr Glu Lys Thr Gln 
    690                 695                 700


Lys Lys Ser Ala Ile Pro Arg Gln Lys Ala Leu Glu Tyr Ala Lys Thr 
705                 710                 715                 720


Ile Pro Lys Pro Lys Pro Ser Asn Leu Thr His Gln Ala Ser Lys Glu 
                725                 730                 735


Gln Lys Asn Pro Thr Tyr Ala Gly Lys Glu Glu Ser Leu Pro Glu Ile 
            740                 745                 750


Ser Leu Leu Glu Ile Leu Gln Asn Arg His Glu Arg Glu Lys Gln Ala 
        755                 760                 765


Val Ala Ala Phe Lys Val Leu His Ile Val 
    770                 775


<210>  8028
<211>  700
<212>  DNA
<213>  Homo sapiens

<400>  8028
aggccagaaa ggatgtcatc acgctaaatg accagttgac acgaagagaa aactggtgcg     60

ttaaggtcaa actattactt actttacatg ctcaatacat actcagggga cccaatttta    120

gaacagttat ctgaactgga tgcagcaagt aacgtttgat cacaccaata gaaacactat    180

gaaataacac tatacgccaa gatgatgacg acaacagaaa taacaatgtt ttctacacat    240

ggaatgctcg cggtgtgcca gcatctgtcc taggccctta gttctcagaa acatgactca    300

tttaaaagaa aaatcaactc tatcttggag gagaaatgaa ggtcaagagt aaaaaaacta    360

actaagctga cttagcaggc aaggaaatca tccttttcaa acctcaaagt ggggatgact    420

gagagaaact gtcgtctgga gcctgggaaa aaaggaagtt gaactctttc atagatctgc    480

catgaggatg ctgattccct gacttttgct gttttggtag aacacagtgg ctgaatcacc    540

ccagtgagat ccctgggcaa gtaaagcata cttctacatt atctctttca aagtggaatg    600

ggacacaacc tctgccagct attttttttt ttttgtgaac cattctatta ataccaatca    660

aatcgagaaa atgatcaaat gaaattgcat tttgagcatc                          700


<210>  8029
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  8029

Met Glu Cys Ser Arg Cys Ala Ser Ile Cys Pro Arg Pro Leu Val Leu 
1               5                   10                  15


Arg Asn Met Thr His Leu Lys Glu Lys Ser Thr Leu Ser Trp Arg Arg 
            20                  25                  30


Asn Glu Gly Gln Glu 
        35


<210>  8030
<211>  750
<212>  DNA
<213>  Homo sapiens

<400>  8030
aaggaaatgg aaaatgctgc catcgatcct gaagataaat ggcatcaaag agcacaacag     60

ctaaagaaca ccaagctgaa aggttatcag aaaagagacg tgaagcttgg aggcctcgga    120

cctgactttg agtccatcag agacaaaacg caaaaattaa tacagcaaaa ggaatatgca    180

aaacaagtca aggagtacaa catgaagaca ctatccattc tatcaaaacc acaaacagaa    240

aaaactcaaa agaaatctgc tatccctcgg cagaaggctt tggaatacgc taagaccatc    300

cccaaaccca aaccatcaaa tctgactcat caagcatcaa aggaacaaaa aaatccaacc    360

tatgctggga aagaagaaag tttacctgaa atctcactgc tggaaatact gcagaacaga    420

cacgaaaggg aaaaacaggc tgtggctgct ttcaaagtcc ttcacatcgt atagacaaca    480

tttgatagga aggagaccaa aaatggtcca ggaatgaacg tggagaaaag aaacgccaac    540

caccttctct gcgttgagag taatggccta ttattatcat ctatctgccg tccatgtttg    600

ctttctgcag gatttaaaat atgaggccca attggattat ggtgccatat tttactttct    660

aggaagaaaa ttttttaaat tatttatttt caaatcagtt agaattggag ctgaataata    720

actagagaat aaagcttttg ttttatattg                                     750


<210>  8031
<211>  155
<212>  PRT
<213>  Homo sapiens

<400>  8031

Met Glu Asn Ala Ala Ile Asp Pro Glu Asp Lys Trp His Gln Arg Ala 
1               5                   10                  15


Gln Gln Leu Lys Asn Thr Lys Leu Lys Gly Tyr Gln Lys Arg Asp Val 
            20                  25                  30


Lys Leu Gly Gly Leu Gly Pro Asp Phe Glu Ser Ile Arg Asp Lys Thr 
        35                  40                  45


Gln Lys Leu Ile Gln Gln Lys Glu Tyr Ala Lys Gln Val Lys Glu Tyr 
    50                  55                  60


Asn Met Lys Thr Leu Ser Ile Leu Ser Lys Pro Gln Thr Glu Lys Thr 
65                  70                  75                  80


Gln Lys Lys Ser Ala Ile Pro Arg Gln Lys Ala Leu Glu Tyr Ala Lys 
                85                  90                  95


Thr Ile Pro Lys Pro Lys Pro Ser Asn Leu Thr His Gln Ala Ser Lys 
            100                 105                 110


Glu Gln Lys Asn Pro Thr Tyr Ala Gly Lys Glu Glu Ser Leu Pro Glu 
        115                 120                 125


Ile Ser Leu Leu Glu Ile Leu Gln Asn Arg His Glu Arg Glu Lys Gln 
    130                 135                 140


Ala Val Ala Ala Phe Lys Val Leu His Ile Val 
145                 150                 155


<210>  8032
<211>  1100
<212>  DNA
<213>  Homo sapiens

<400>  8032
aaatacagga acttagaaat gttatggaaa ttccattctt cttctgacag ccagacggtt     60

agagcttctc cagattcatg gctcacccag ataatggagc agcatcagca agccttggtg    120

cagctgaccg acgtgcagcc cagtgaaggg gccttatcca gcgtcacgct tccacctata    180

ctgtcaaggg tagaaagtga atcccaactc agttcagaga gaagccaaag aaaccaagtg    240

aaaattagcc gtagcaattc tgaaggctat ctgtttcaac tggaaaaggg aaaaaagcat    300

aagaaaagaa gcagcagtaa ggtaataaaa gcgccatttt taccaagtaa ctcttccatt    360

ttgagaatac agatggacct tgatgtaatt atagccctgg aatagggatg gtcattactg    420

agttgctgcc acactgggtc gcccagagtc ctaaggagtt tcttactcct gcccctgcta    480

ctccctgggg tttccctccc cttcttaata gaagttgttg ctgccaggga tgcccatttc    540

tccctcctgt tcaagtcatc ttggcgagag gtctccattt gcagagtggc agaactcctc    600

ctttcatccc cagctgaaac atctcttcct taggaaagct tccatactcc accccaagcc    660

ccatgctaac ctgagtcttc atggttatta aatcatttct tcccaggtca ttctcatatc    720

ttaaaaagta gagaaagtag ggctgagtga gtgaaagcgc ctgttgccat tgcattttcc    780

caccatctgc cactatgagg actcatcttg gccctaatct caccccaact tctgcagtaa    840

aatacctggg ctggccagtg attgaacttt cctctcaaac attagctgac ctttactgag    900

ttctttgtct caaatcacca ttactagcac ctttgcgcac ttcagtcttt tctcataggg    960

cctacatgat ttaacaagta aaattgggga cccaaagtag aatgttttca gtaagaaatg   1020

aaggcgccta ggaaggggac tttttatgtc ctgtgtattt ctcttctgtc actggcaata   1080

aaaagccctc aggaaaggtc                                               1100


<210>  8033
<211>  128
<212>  PRT
<213>  Homo sapiens

<400>  8033

Met Leu Trp Lys Phe His Ser Ser Ser Asp Ser Gln Thr Val Arg Ala 
1               5                   10                  15


Ser Pro Asp Ser Trp Leu Thr Gln Ile Met Glu Gln His Gln Gln Ala 
            20                  25                  30


Leu Val Gln Leu Thr Asp Val Gln Pro Ser Glu Gly Ala Leu Ser Ser 
        35                  40                  45


Val Thr Leu Pro Pro Ile Leu Ser Arg Val Glu Ser Glu Ser Gln Leu 
    50                  55                  60


Ser Ser Glu Arg Ser Gln Arg Asn Gln Val Lys Ile Ser Arg Ser Asn 
65                  70                  75                  80


Ser Glu Gly Tyr Leu Phe Gln Leu Glu Lys Gly Lys Lys His Lys Lys 
                85                  90                  95


Arg Ser Ser Ser Lys Val Ile Lys Ala Pro Phe Leu Pro Ser Asn Ser 
            100                 105                 110


Ser Ile Leu Arg Ile Gln Met Asp Leu Asp Val Ile Ile Ala Leu Glu 
        115                 120                 125


<210>  8034
<211>  5113
<212>  DNA
<213>  Homo sapiens

<400>  8034
ggtaggaggc aaccatgtgg ttccagctga attttttttt tccctctctc tttcttcact     60

cctttttctt tccaaacagg gaaaagtgtt ccacgaagcg gtagcgcctt ttcgcctcgc    120

gttttcctcc ctgaccctgg tcccggctcc cgtccgggcg ccagctggtg gggcgagcgc    180

cgggagccca tctgccccca ggggcacggg gcgcggggcc ggctcccgcc cggcacatgg    240

ctgcagccac ctcgcgcgca ccccgaggcg ccgcgcccag ctcgcccgag gtccgtcgga    300

ggcgcccggc cgccccggag ccaagcagca gctgagcggg gaagcgcccg cgtccgggga    360

tcgggatgtc cctcctcctt ctcctcttgc tagtttccta ctatgttgga accttgggga    420

ctcacactga gatcaagaga gtggcagagg aaaaggtcac tttgccctgc caccatcaac    480

tggggcttcc agaaaaagac actctggata ttgaatggct gctcaccgat aatgaaggga    540

accaaaaagt ggtgatcact tactccagtc gtcatgtcta caataacttg actgaggaac    600

agaagggccg agtggccttt gcttccaatt tcctggcagg agatgcctcc ttgcagattg    660

aacctctgaa gcccagtgat gagggccggt acacctgtaa ggttaagaat tcagggcgct    720

acgtgtggag ccatgtcatc ttaaaagtct tagtgagacc atccaagccc aagtgtgagt    780

tggaaggaga gctgacagaa ggaagtgacc tgactttgca gtgtgagtca tcctctggca    840

cagagcccat tgtgtattac tggcagcgaa tccgagagaa agagggagag gatgaacgtc    900

tgcctcccaa atctaggatt gactacaacc accctggacg agttctgctg cagaatctta    960

ccatgtccta ctctggactg taccagtgca cagcaggcaa cgaagctggg aaggaaagct   1020

gtgtggtgcg agtaactgta cagtatgtac aaagcatcgg catggttgca ggagcagtga   1080

caggcatagt ggctggagcc ctgctgattt tcctcttggt gtggctgcta atccgaagga   1140

aagacaaaga aagatatgag gaagaagaga gacctaatga aattcgagaa gatgctgaag   1200

ctccaaaagc ccgtcttgtg aaacccagct cctcttcctc aggctctcgg agctcacgct   1260

ctggttcttc ctccactcgc tccacagcaa atagtgcctc acgcagccag cggacactgt   1320

caactgacgc agcaccccag ccagggctgg ccacccaggc atacagccta gtggggccag   1380

aggtgagagg ttctgaacca aagaaagtcc accatgctaa tctgaccaaa gcagaaacca   1440

cacccagcat gatccccagc cagagcagag ccttccaaac ggtctgaatt acaatggact   1500

tgactcccac gctttcctag gagtcagggt ctttggactc ttctcgtcat tggagctcaa   1560

gtcaccagcc acacaaccag atgagaggtc atctaagtag cagtgagcat tgcacggaac   1620

agattcagat gagcattttc cttatacaat accaaacaag caaaaggatg taagctgatt   1680

catctgtaaa aaggcatctt attgtgcctt tagaccagag taagggaaag caggagtcca   1740

aatctatttg ttgaccagga cctgtggtga gaaggttggg gaaaggtgag gtgaatatac   1800

ctaaaacttt taatgtggga tattttgtat cagtgctttg attcacaatt ttcaagagga   1860

aatgggatgc tgtttgtaaa ttttctatgc atttctgcaa acttattgga ttattagtta   1920

ttcagacagt caagcagaac ccacagcctt attacacctg tctacaccat gtactgagct   1980

aaccacttct aagaaactcc aaaaaaggaa acatgtgtct tctattctga cttaacttca   2040

tttgtcataa ggtttggata ttaatttcaa ggggagttga aatagtggga gatggagaag   2100

agtgaatgag tttctcccac tctatactaa tctcactatt tgtattgagc ccaaaataac   2160

tatgaaagga gacaaaaatt tgtgacaaag gattgtgaag agctttccat cttcatgatg   2220

ttatgaggat tgttgacaaa cattagaaat atataatgga gcaattgtgg atttcccctc   2280

aaatcagatg cctctaagga ctttcctgct agatatttct ggaaggagaa aatacaacat   2340

gtcatttatc aacgtcctta gaaagaattc ttctagagaa aaagggatct aggaatgctg   2400

aaagattacc caacatacca ttatagtctc ttctttctga gaaaatgtga aaccagaatt   2460

gcaagactgg gtggactaga aagggagatt agatcagttt tctcttaata tgtcaaggaa   2520

ggtagccggg catggtgcca ggcacctgta ggaaaatcca gcaggtggag gttgcagtga   2580

gccaagatta tgccattgca ctccagcctg ggtgacaaag caagactcca tctcaaaaaa   2640

aaaaaaaaat caaggaagga taaaaggaag ttcagtattg taccacactt ggaacttcct   2700

ccatttcttc cattttagaa ggatatgaac ctggaacttt tgatgattct aagccttaaa   2760

ctatcaaaaa gatcagggat tgccaatgct tctaatggca ctgcaagtat atgccataac   2820

cgttccctcc taaaagtgaa aaatgagaga aattcagtat tttcccaggc tcagcatcca   2880

gaagtctagc tctgggctgg aagaaaaggg tactaatatt tagggaagag atgagaataa   2940

gtagtgggtg gcaggagagg gctgagctag tgcctgctaa cattttagtt gtatcttgga   3000

aagatttagc aaaaataact caccaggata gctgctgaag agttgatgaa tgggagaaga   3060

aagatgtttg agaaataaag aaaacagcag cctgcaatac aataacttgc ctttttaata   3120

gttttgatta ctcttgatac ctacagcaca aatgctggac ctgaatcagc tcttcaagga   3180

ccctagcaca aatgtcaact gatcacctct gggagagtag aaaacttttt tttttttgag   3240

acgaagtctc gctctgttgc ccaggctgga gtgcagtggc accatctcag ctcactgcag   3300

cgtccgcctc ttgggttcaa gtgattctcc tgccttgtcc tcctgagtcg ctggtattac   3360

aggtgcctgc catcacaccc agctaatttt tggagttctg atagagacag ggtttctcca   3420

tgttggccag gcttgtctca agctcctgac ctcaagtgac ctacccaccc ttggcctccc   3480

acagtgctgg aagccactgc acctggctca gaatactttt ttttttgaga tgcagtcttg   3540

ctctcatcac gcaggctgga gtgcagtggc gtatctcggc tcactgcgac ctccacctcc   3600

cgagttcaag cgattctcct tcctcagtcc cccaagtagc ttggattata ggtgtgcgcc   3660

accacgtaca gctaattttt gtatttttag tagagatggg gtttcgccat gttgaccagg   3720

ctggtctcaa aacgcctgac ctcaggtgat ccacccacct cggccccaca aagtgctagg   3780

attacaggtg tgagccacca tgcccggccc agaatacttt ttaaaagaag agcaggttag   3840

aggaaagaaa aaaattgatg ctgaatgtgg tgatgaaagc atgtttctaa aatgggaagc   3900

agatgcttaa agaggaaaga ctaatctggg attttgcccc atttctctgg tttttcactc   3960

ctatatttaa ttctcacaat cgtgtcgtca catagtgcaa aaaacaaaat tcttgtaaag   4020

tccccaggag tttatgcttg ggtgaaagtt ttagcctgag tattttcttc ctctaaaaaa   4080

ggtgggaaat gagacattga ggaattaaca tataaatgtc tgctatgggt ttaagagaac   4140

tggcgtattt ggaatgcttc ttacactaac actgtctcat tgtaaaatat aaaacccctt   4200

actctaacta catttttatt cctctggtag tgtggtatcc aggcaacata tcacttctgc   4260

tatgtaattc taagaattct catttctaga gtacctgagc caaacaaata cacaacggaa   4320

gctgcagctg tatcatcact agcaatttgc tcatcattat ttactacctt tgaacctaag   4380

gtttcctgcc tatgcttttg aaagcaaaaa tcagtctcct ttgcatgaaa aagagcctta   4440

gatttttaaa catgttagtt accagaatgc taaaatacca gttgattacc caaattattt   4500

tggaaatcta tccataatgg aagtctacaa caaacacata aaacagatta cactaagagc   4560

tgagaaattc aaaggaactg aagattctga gagataaact gttcaagtct tagcaatgat   4620

actgcacttc tctttgacag gttctgggct taagttagag gccctactgg ttccaaacca   4680

tattccactg actttgcaag taaaataaat ttgattctga aataggaaac aaaaaaagga   4740

gaaataaccg aatagtagaa gaaaaactgt ttgtaggaag acgatgcaga tggaatgatg   4800

tggacattga gtaaccatgt caataaaata tataaaccaa acttaaattt gtgaaataag   4860

gaagttggta cctttgttgt tacagtgtat aaaaacaatt tcggaactgc tgttgcaaaa   4920

agacatatat agttttgctt ccttctggtg ttaagctgtt tatatttcag tttcagtttt   4980

aacttctaag ttgccttgta attgggactg tgtttcagca tcacaaaaac caaatattta   5040

ttatggatgc atctgtatca gcaattaaaa aataaacaag taaaagtgat actgtaggag   5100

aagctgaagc tca                                                      5113


<210>  8035
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  8035

Met Ser Leu Leu Leu Leu Leu Leu Leu Val Ser Tyr Tyr Val Gly Thr 
1               5                   10                  15


Leu Gly Thr His Thr Glu Ile Lys Arg Val Ala Glu Glu Lys Val Thr 
            20                  25                  30


Leu Pro Cys His His Gln Leu Gly Leu Pro Glu Lys Asp Thr Leu Asp 
        35                  40                  45


Ile Glu Trp Leu Leu Thr Asp Asn Glu Gly Asn Gln Lys Val Val Ile 
    50                  55                  60


Thr Tyr Ser Ser Arg His Val Tyr Asn Asn Leu Thr Glu Glu Gln Lys 
65                  70                  75                  80


Gly Arg Val Ala Phe Ala Ser Asn Phe Leu Ala Gly Asp Ala Ser Leu 
                85                  90                  95


Gln Ile Glu Pro Leu Lys Pro Ser Asp Glu Gly Arg Tyr Thr Cys Lys 
            100                 105                 110


Val Lys Asn Ser Gly Arg Tyr Val Trp Ser His Val Ile Leu Lys Val 
        115                 120                 125


Leu Val Arg Pro Ser Lys Pro Lys Cys Glu Leu Glu Gly Glu Leu Thr 
    130                 135                 140


Glu Gly Ser Asp Leu Thr Leu Gln Cys Glu Ser Ser Ser Gly Thr Glu 
145                 150                 155                 160


Pro Ile Val Tyr Tyr Trp Gln Arg Ile Arg Glu Lys Glu Gly Glu Asp 
                165                 170                 175


Glu Arg Leu Pro Pro Lys Ser Arg Ile Asp Tyr Asn His Pro Gly Arg 
            180                 185                 190


Val Leu Leu Gln Asn Leu Thr Met Ser Tyr Ser Gly Leu Tyr Gln Cys 
        195                 200                 205


Thr Ala Gly Asn Glu Ala Gly Lys Glu Ser Cys Val Val Arg Val Thr 
    210                 215                 220


Val Gln Tyr Val Gln Ser Ile Gly Met Val Ala Gly Ala Val Thr Gly 
225                 230                 235                 240


Ile Val Ala Gly Ala Leu Leu Ile Phe Leu Leu Val Trp Leu Leu Ile 
                245                 250                 255


Arg Arg Lys Asp Lys Glu Arg Tyr Glu Glu Glu Glu Arg Pro Asn Glu 
            260                 265                 270


Ile Arg Glu Asp Ala Glu Ala Pro Lys Ala Arg Leu Val Lys Pro Ser 
        275                 280                 285


Ser Ser Ser Ser Gly Ser Arg Ser Ser Arg Ser Gly Ser Ser Ser Thr 
    290                 295                 300


Arg Ser Thr Ala Asn Ser Ala Ser Arg Ser Gln Arg Thr Leu Ser Thr 
305                 310                 315                 320


Asp Ala Ala Pro Gln Pro Gly Leu Ala Thr Gln Ala Tyr Ser Leu Val 
                325                 330                 335


Gly Pro Glu Val Arg Gly Ser Glu Pro Lys Lys Val His His Ala Asn 
            340                 345                 350


Leu Thr Lys Ala Glu Thr Thr Pro Ser Met Ile Pro Ser Gln Ser Arg 
        355                 360                 365


Ala Phe Gln Thr Val 
    370


<210>  8036
<211>  4860
<212>  DNA
<213>  Homo sapiens

<400>  8036
ggtaggaggc aaccatgtgg ttccagctga attttttttt tccctctctc tttcttcact     60

cctttttctt tccaaacagg gaaaagtgtt ccacgaagcg gtagcgcctt ttcgcctcgc    120

gttttcctcc ctgaccctgg tcccggctcc cgtccgggcg ccagctggtg gggcgagcgc    180

cgggagccca tctgccccca ggggcacggg gcgcggggcc ggctcccgcc cggcacatgg    240

ctgcagccac ctcgcgcgca ccccgaggcg ccgcgcccag ctcgcccgag gtccgtcgga    300

ggcgcccggc cgccccggag ccaagcagca gctgagcggg gaagcgcccg cgtccgggga    360

tcgggatgtc cctcctcctt ctcctcttgc tagtttccta ctatgttgga accttgggga    420

ctcacactga gatcaagaga gtggcagagg aaaaggtcac tttgccctgc caccatcaac    480

tggggcttcc agaaaaagac actctggata ttgaatggct gctcaccgat aatgaaggga    540

accaaaaagt ggtgatcact tactccagtc gtcatgtcta caataacttg actgaggaac    600

agaagggccg agtggccttt gcttccaatt tcctggcagg agatgcctcc ttgcagattg    660

aacctctgaa gcccagtgat gagggccggt acacctgtaa ggttaagaat tcagggcgct    720

acgtgtggag ccatgtcatc ttaaaagtct tagtgagacc atccaagccc aagtgtgagt    780

tggaaggaga gctgacagaa ggaagtgacc tgactttgca gtgtgagtca tcctctggca    840

cagagcccat tgtgtattac tggcagcgaa tccgagagaa agagggagag gatgaacgtc    900

tgcctcccaa atctaggatt gactacaacc accctggacg agttctgctg cagaatctta    960

ccatgtccta ctctggactg taccagtgca cagcaggcaa cgaagctggg aaggaaagct   1020

gtgtggtgcg agtaactgta cagtatgtac aaagcatcgg catggttgca ggagcagtga   1080

caggcatagt ggctggagcc ctgctgattt tcctcttggt gtggctgcta atccgaagga   1140

aagacaaaga aagatatgag gaagaagaga gacctaatga aattcgagaa gatgctgaag   1200

ctccaaaagc ccgtcttgtg aaacccagct cctcttcctc aggctctcgg agctcacgct   1260

ctggttcttc ctccactcgc tccacagcaa atagtgcctc acgcagccag cggacactgt   1320

caactgacgc agcaccccag ccagggctgg ccacccaggc atacagccta gtggggccag   1380

aggtgagagg ttctgaacca aagaaagtcc accatgctaa tctgaccaaa gcagaaacca   1440

cacccagcat gatccccagc cagagcagag ccttccaaac ggtctgaatt acaatggact   1500

tgactcccac gctttcctag gagtcagggt ctttggactc ttctcgtcat tggagctcaa   1560

gtcaccagcc acacaaccag atgagaggtc atctaagtag cagtgagcat tgcacggaac   1620

agattcagat gagcattttc cttatacaat accaaacaag caaaaggatg taagctgatt   1680

catctgtaaa aaggcatctt attgtgcctt tagaccagag taagggaaag caggagtcca   1740

aatctatttg ttgaccagga cctgtggtga gaaggttggg gaaaggtgag gtgaatatac   1800

ctaaaacttt taatgtggga tattttgtat cagtgctttg attcacaatt ttcaagagga   1860

aatgggatgc tgtttgtaaa ttttctatgc atttctgcaa acttattgga ttattagtta   1920

ttcagacagt caagcagaac ccacagcctt attacacctg tctacaccat gtactgagct   1980

aaccacttct aagaaactcc aaaaaaggaa acatgtgtct tctattctga cttaacttca   2040

tttgtcataa ggtttggata ttaatttcaa ggggagttga aatagtggga gatggagaag   2100

agtgaatgag tttctcccac tctatactaa tctcactatt tgtattgagc ccaaaataac   2160

tatgaaagga gacaaaaatt tgtgacaaag gattgtgaag agctttccat cttcatgatg   2220

ttatgaggat tgttgacaaa cattagaaat atataatgga gcaattgtgg atttcccctc   2280

aaatcagatg cctctaagga ctttcctgct agatatttct ggaaggagaa aatacaacat   2340

gtcatttatc aacgtcctta gaaagaattc ttctagagaa aaagggatct aggaatgctg   2400

aaagattacc caacatacca ttatagtctc ttctttctga gaaaatgtga aaccagaatt   2460

gcaagactgg gtggactaga aagggagatt agatcagttt tctcttaata tgtcaaggaa   2520

ggtagccggg catggtgcca ggcacctgta ggaaaatcca gcaggtggag gttgcagtga   2580

gccaagatta tgccattgca ctccagcctg ggtgacaaag caagactcca tctcaaaaaa   2640

aaaaaaaaat caaggaagga taaaaggaag ttcagtattg taccacactt ggaacttcct   2700

ccatttcttc cattttagaa ggatatgaac ctggaacttt tgatgattct aagccttaaa   2760

ctatcaaaaa gatcagggat tgccaatgct tctaatggca ctgcaagtat atgccataac   2820

cgttccctcc taaaagtgaa aaatgagaga aattcagtat tttcccaggc tcagcatcca   2880

gaagtctagc tctgggctgg aagaaaaggg tactaatatt tagggaagag atgagaataa   2940

gtagtgggtg gcaggagagg gctgagctag tgcctgctaa cattttagtt gtatcttgga   3000

aagatttagc aaaaataact caccaggata gctgctgaag agttgatgaa tgggagaaga   3060

aagatgtttg agaaataaag aaaacagcag cctgcaatac aataacttgc ctttttaata   3120

gttttgatta ctcttgatac ctacagcaca aatgctggac ctgaatcagc tcttcaagga   3180

ccctagcaca aatgtcaact gatcacctct gggagagtag aaaacttttt tttttttgag   3240

acgaagtctc gctctgttgc ccaggctgga gtgcagtggc accatctcag ctcactgcag   3300

cgtccgcctc ttgggttcaa gtgattctcc tgccttgtcc tcctgagtcg ctggtattac   3360

aggtgcctgc catcacaccc agctaatttt tggagttctg atagagacag ggtttctcca   3420

tgttggccag gcttgtctca agctcctgac ctcaagtgac ctacccaccc ttggcctccc   3480

acagtgctgg aagccactgc acctggctca gaatactttt ttttttgaga tgcagtcttg   3540

ctctcatcac gcaggctgga gtgcagtggc gtatctcggc tcactgcgac ctccacctcc   3600

cgagttcaag cgattctcct tcctcagtcc cccaagtagc ttggattata ggtgtgcgcc   3660

accacgtaca gctaattttt gtatttttag tagagatggg gtttcgccat gttgaccagg   3720

ctggtctcaa aacgcctgac ctcaggtgat ccacccacct cggccccaca aagtgctagg   3780

attacaggtg tgagccacca tgcccggccc agaatacttt ttaaaagaag agcaggttag   3840

aggaaagaaa aaaattgatg ctgaatgtgg tgatgaaagc atgtttctaa aatgggaagc   3900

agatgcttaa agaggaaaga ctaatctggg attttgcccc atttctctgg tttttcactc   3960

ctatatttaa ttctcacaat cgtgtcgtca catagtgcaa aaaacaaaat tcttgtaaag   4020

tccccaggag tttatgcttg ggtgaaagtt ttagcctgag tattttcttc ctctaaaaaa   4080

ggtgggaaat gagacattga ggaattaaca tataaatgtc tgctatgggt ttaagagaac   4140

tggcgtattt ggaatgcttc ttacactaac actgtctcat tgtaaaatat aaaacccctt   4200

actctaacta catttttatt cctctggtag tgtggtatcc aggcaacata tcacttctgc   4260

tatgtaattc taagaattct catttctaga gtacctgagc caaacaaata cacaacggaa   4320

gctgcagctg tatcatcact agcaatttgc tcatcattat ttactacctt tgaacctaag   4380

gtttcctgcc tatgcttttg aaagcaaaaa tcagtctcct ttgcatgaaa aagagcctta   4440

gatttttaaa catgttagtt accagaatgc taaaatacca gttgattacc caaattattt   4500

tggaaatcta tccataatgg aagtctacaa caaacacata aaacagatta cactaagagc   4560

tgagaaattc aaaggaactg aagattctga gagataaact gttcaagtct tagcaatgat   4620

actgcacttc tctttgacag gttctgggct taagttagag gccctactgg ttccaaacca   4680

tattccactg actttgcaag taaaataaat ttgattctga aataggaaac aaaaaaagga   4740

gaaataaccg aatagtagaa gaaaaactgt ttgtaggaag acgatgcaga tggaatgatg   4800

tggacattga gtaaccatgt caataaaata tataaaccaa acttaaattt gtgaaataag   4860


<210>  8037
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  8037

Met Ser Leu Leu Leu Leu Leu Leu Leu Val Ser Tyr Tyr Val Gly Thr 
1               5                   10                  15


Leu Gly Thr His Thr Glu Ile Lys Arg Val Ala Glu Glu Lys Val Thr 
            20                  25                  30


Leu Pro Cys His His Gln Leu Gly Leu Pro Glu Lys Asp Thr Leu Asp 
        35                  40                  45


Ile Glu Trp Leu Leu Thr Asp Asn Glu Gly Asn Gln Lys Val Val Ile 
    50                  55                  60


Thr Tyr Ser Ser Arg His Val Tyr Asn Asn Leu Thr Glu Glu Gln Lys 
65                  70                  75                  80


Gly Arg Val Ala Phe Ala Ser Asn Phe Leu Ala Gly Asp Ala Ser Leu 
                85                  90                  95


Gln Ile Glu Pro Leu Lys Pro Ser Asp Glu Gly Arg Tyr Thr Cys Lys 
            100                 105                 110


Val Lys Asn Ser Gly Arg Tyr Val Trp Ser His Val Ile Leu Lys Val 
        115                 120                 125


Leu Val Arg Pro Ser Lys Pro Lys Cys Glu Leu Glu Gly Glu Leu Thr 
    130                 135                 140


Glu Gly Ser Asp Leu Thr Leu Gln Cys Glu Ser Ser Ser Gly Thr Glu 
145                 150                 155                 160


Pro Ile Val Tyr Tyr Trp Gln Arg Ile Arg Glu Lys Glu Gly Glu Asp 
                165                 170                 175


Glu Arg Leu Pro Pro Lys Ser Arg Ile Asp Tyr Asn His Pro Gly Arg 
            180                 185                 190


Val Leu Leu Gln Asn Leu Thr Met Ser Tyr Ser Gly Leu Tyr Gln Cys 
        195                 200                 205


Thr Ala Gly Asn Glu Ala Gly Lys Glu Ser Cys Val Val Arg Val Thr 
    210                 215                 220


Val Gln Tyr Val Gln Ser Ile Gly Met Val Ala Gly Ala Val Thr Gly 
225                 230                 235                 240


Ile Val Ala Gly Ala Leu Leu Ile Phe Leu Leu Val Trp Leu Leu Ile 
                245                 250                 255


Arg Arg Lys Asp Lys Glu Arg Tyr Glu Glu Glu Glu Arg Pro Asn Glu 
            260                 265                 270


Ile Arg Glu Asp Ala Glu Ala Pro Lys Ala Arg Leu Val Lys Pro Ser 
        275                 280                 285


Ser Ser Ser Ser Gly Ser Arg Ser Ser Arg Ser Gly Ser Ser Ser Thr 
    290                 295                 300


Arg Ser Thr Ala Asn Ser Ala Ser Arg Ser Gln Arg Thr Leu Ser Thr 
305                 310                 315                 320


Asp Ala Ala Pro Gln Pro Gly Leu Ala Thr Gln Ala Tyr Ser Leu Val 
                325                 330                 335


Gly Pro Glu Val Arg Gly Ser Glu Pro Lys Lys Val His His Ala Asn 
            340                 345                 350


Leu Thr Lys Ala Glu Thr Thr Pro Ser Met Ile Pro Ser Gln Ser Arg 
        355                 360                 365


Ala Phe Gln Thr Val 
    370


<210>  8038
<211>  630
<212>  DNA
<213>  Homo sapiens

<400>  8038
aggcaaccat gtggttccag ctgaattttt tttttccctc tctctttctt cactcctttt     60

tctttccaaa cagggaaaag tgttccacga agcggtagcg ccttttcgcc tcgcgttttc    120

ctccctgacc ctggtcccgg ctcccgtccg ggcgccagct ggtggggcga gcgccgggag    180

cccatctgcc cccaggggca cggggcgcgg ggccggctcc cgcccggcac atggctgcag    240

ccacctcgcg cgcaccccga ggcgccgcgc ccagctcgcc cgaggtccgt cggaggcgcc    300

cggccgcccc ggagccaagc agcagctgag cggggaagcg cccgcgtccg gggatcggga    360

tgtccctcct ccttctcctc ttgctagttt cctactatgt tggaaccttg gggactcaca    420

ctgagatcaa gagagtggca gaggaaaagg tcactttgcc ctgccaccat caactggggc    480

ttccagaaaa agacactctg gatattgaat ggctgctcac cgataatgaa gggaaccaaa    540

aagtggttct tgcggtcttt ctgactagag ctaatcttgg acttccctct ctgccctcgt    600

agaatacatt ttgagcaaga atgctgctaa                                     630


<210>  8039
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  8039

Met Ser Leu Leu Leu Leu Leu Leu Leu Val Ser Tyr Tyr Val Gly Thr 
1               5                   10                  15


Leu Gly Thr His Thr Glu Ile Lys Arg Val Ala Glu Glu Lys Val Thr 
            20                  25                  30


Leu Pro Cys His His Gln Leu Gly Leu Pro Glu Lys Asp Thr Leu Asp 
        35                  40                  45


Ile Glu Trp Leu Leu Thr Asp Asn Glu Gly Asn Gln Lys Val Val Leu 
    50                  55                  60


Ala Val Phe Leu Thr Arg Ala Asn Leu Gly Leu Pro Ser Leu Pro Ser 
65                  70                  75                  80


<210>  8040
<211>  604
<212>  DNA
<213>  Homo sapiens

<400>  8040
gtactggggc aaccccatag ctgggggtcc tatgggagag actgaggaac ttcggtttgt     60

ggactctcag tcaactgtgt tactgaggag gggaaaggaa agtagatgag ttggtggttt    120

gaacaagacc caaatcttgc ttctacttat aggtgctcac aatggccagt gccctggaaa    180

agctctggaa taaatacacc tgggccttag aaagcagagg caggagacaa tgccatccag    240

tgggagcttt catttgtttc ctcagccagc ctctgtgtca ggctttttgg gaacaagggc    300

tggatgaaca agaccttggg agttcctgtg gggagggact gggggtgaat gggcagtgtg    360

gctggcccgg tgatcacttc tcctctgctt gtctaggctt gaggatggat tcttggctcc    420

tggtgcattg ccactccctg ccaccctcct ccttgtcttc tatcttctcc tggtggcgtc    480

aggccttgct tcgtgtccca acaggagcct ctggggctgg cacagccctc actgcctaca    540

acctgggcct ggtggttctc ctagggtgcc tctgggaggt catggtcacc ccgctgctgg    600

ctaa                                                                 604


<210>  8041
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  8041

Met Ala Ser Ala Leu Glu Lys Leu Trp Asn Lys Tyr Thr Trp Ala Leu 
1               5                   10                  15


Glu Ser Arg Gly Arg Arg Gln Cys His Pro Val Gly Ala Phe Ile Cys 
            20                  25                  30


Phe Leu Ser Gln Pro Leu Cys Gln Ala Phe Trp Glu Gln Gly Leu Asp 
        35                  40                  45


Glu Gln Asp Leu Gly Ser Ser Cys Gly Glu Gly Leu Gly Val Asn Gly 
    50                  55                  60


Gln Cys Gly Trp Pro Gly Asp His Phe Ser Ser Ala Cys Leu Gly Leu 
65                  70                  75                  80


Arg Met Asp Ser Trp Leu Leu Val His Cys His Ser Leu Pro Pro Ser 
                85                  90                  95


Ser Leu Ser Ser Ile Phe Ser Trp Trp Arg Gln Ala Leu Leu Arg Val 
            100                 105                 110


Pro Thr Gly Ala Ser Gly Ala Gly Thr Ala Leu Thr Ala Tyr Asn Leu 
        115                 120                 125


Gly Leu Val Val Leu Leu Gly Cys Leu Trp Glu Val Met Val Thr Pro 
    130                 135                 140


Leu Leu 
145


<210>  8042
<211>  4843
<212>  DNA
<213>  Homo sapiens

<400>  8042
tgagatcgtg tttcatttca ggaagatata tgcgtcagga aaatttctat cttcttttgt     60

attatcaagg agatatttgg agcagagtca accctctcag ttacataaaa taaaaaatgg    120

catattcttg gcaaacggat ccaaatccta atgaatcaca cgaaaagcag tatgaacacc    180

aagaatttct ctttgtaaat caaccccatt cttctagcca agtcagtctg ggttttgatc    240

agatagtaga tgagatcagt ggcaaaattc cacactacga gagtgaaatt gatgaaaaca    300

ccttttttgt gcccactgca ccaaaatggg actcaacagg gcattcatta aatgaagcac    360

accaaatatc cttgaatgaa ttcacttcta aaagccgtga actctcctgg catcaagtta    420

gcaaagcacc agcaattggt tttagtcctt ctgtgttacc aaaacctcaa aatacgaata    480

aagaatgctc ctggggaagc cccataggaa aacatcatgg tgctgatgat tccagattca    540

gtattttagc tccatcattc acaagtttgg ataaaattaa tctagagaaa gaattagaaa    600

atgaaaatca taactaccat ataggatttg aaagtagcat tcctccaaca aattcatcct    660

tctcaagtga cttcatgccg aaagaagaga ataaaaggag tggacatgtg aacattgtgg    720

aaccatcttt gatgcttttg aaaggctctc ttcaacccgg aatgtgggaa agtacatggc    780

agaagaatat agagtcaata ggttgttcca ttcagctagt ggaagtacct caaagcagca    840

atacgagtct ggcctctttt tgcaacaaag taaaaaaaat cagagaaaga tatcatgcag    900

ctgatgttaa tttcaattct gggaagatct ggagcactac tacagcattt ccgtatcagc    960

tcttttctaa gaccaagttt aatatacata tttttattga taactcaaca caacctcttc   1020

attttatgcc atgtgctaat tatcttgtca aagatctaat tgcagaaatt ctgcattttt   1080

gcacaaatga ccagctactc cccaaagatc atattctaag tgtatgtggc tctgaagaat   1140

ttttacaaaa cgaccactgt ttggggagcc acaaaatgtt tcaaaaagat aaatctgtta   1200

ttcagctcca cctgcagaaa agtagggaag ctccaggaaa gctatctcga aagcatgaag   1260

aggaccacag tcagttttat ctgaatcaac ttctagaatt tatgcatatt tggaaagtat   1320

ccagacaatg tctcttaaca ctcatcagaa aatatgactt ccacctgaaa tacctattga   1380

aaacccagga aaacgtgtat aatattattg aagaagttaa aaaaatatgc agtgttctag   1440

ggtgtgtgga aaccaaacaa attacagatg cagtaaatga actaagtcta attcttcaga   1500

gaaaaggaga gaatttttat caaagttcag agacttcagc aaaaggcttg atagagaagg   1560

taacaactga actatccaca tccatctacc agctaatcaa tgtctactgt aacagctttt   1620

atgcagattt tcagcctgta aatgtaccta gatgcacttc ctatctaaat cccgggcttc   1680

cttcccacct cagcttcaca gtgtatgcag cacacaacat tccagaaacc tgggtgcaca   1740

ggatcaattt tccccttgaa ataaagtcac ttccaaggga atccatgctc actgtaaaac   1800

tgtttgggat tgcctgtgca accaacaatg caaatttact ggcgtggact tgtcttccac   1860

tgtttccaaa agaaaaatcc attctcgggt ctatgctgtt cagcatgaca ttacagagtg   1920

agcctcccgt agaaatgata actccaggag tgtgggatgt aagtcagcca tccccggtga   1980

ccctgcagat tgattttcca gctactgggt gggagtatat gaaacctgat tctgaagaga   2040

atagaagtaa tcttgaagag ccactaaagg agtgtataaa acatattgcc agactttcac   2100

agaaacagac tcccctacta ctctctgaag aaaagaaaag atatttatgg ttttatcgct   2160

tctactgcaa taatgaaaac tgctcccttc ctttagtcct gggtagtgcc cctggatggg   2220

atgaaaggac tgtttcagaa atgcatacca ttttgagaag atggacattt tctcaacctt   2280

tagaggctct tgggcttttg acttccagtt ttccagatca agaaattcgt aaagtggcag   2340

ttcaacaatt agacaacctc ttgaatgatg aactactgga atatctccca cagctagttc   2400

aggctgtcaa gtttgaatgg aaccttgaga gtcctttagt gcaacttcta ctccaccgct   2460

ccttgcagag catccaggtt gcccatcgtc tttactggct gctaaaaaat gcagaaaatg   2520

aagcttattt taaaagctgg tatcagaagc tactagctgc tctccaattc tgtgcaggta   2580

aagccttgaa tgatgagttt tccaaggagc agaaacttat caaaattctg ggagatattg   2640

gggaaagagt caagtctgcc agtgaccatc aaagacagga ggtactgaag aaagaaattg   2700

gcagactaga agagttcttt caagatgtaa atacttgtca tcttcctctg aaccctgccc   2760

tatgtataaa agggattgat cacgatgcat gttcatattt tacatctaat gctttgccat   2820

tgaagattac tttcatcaat gctaatccga tgggcaaaaa catcagcatt atttttaagg   2880

ctggagatga tcttcgtcag gatatgcttg ttctgcagct tattcaagtg atggacaata   2940

tttggctgca ggaaggcttg gatatgcaaa tgatcattta tagatgtcta tccacaggaa   3000

aagaccaagg attggtgcag atggtacctg atgctgtgac cctagcaaag attcatcgcc   3060

attctggact gataggacca ttgaaagaaa atacaattaa aaagtggttc agtcagcaca   3120

accacttaaa ggcagattat gaaaaggcct tgaggaactt tttctactcc tgtgctggct   3180

ggtgtgtggt aacattcatc ctgggagtat gtgaccgtca caatgataat atcatgctga   3240

caaagtcggg ccacatgttt catattgact ttggaaaatt cttaggtcat gcacaaacat   3300

ttggagggat aaaaagggac cgagctcctt tcatttttac ttcagagatg gaatacttta   3360

ttacagaggg tgggaaaaac ccacagcatt ttcaagattt tgtggaactt tgctgtcgtg   3420

cttataatat tatcagaaag cacagccaac tgctcttgaa cctgctggaa atgatgctgt   3480

atgcaggact gcctgagcta agtggaattc aagacctgaa atatgtgtat aataatcttc   3540

gtccacaaga cacagacctg gaagcaacaa gtcattttac caagaaaata aaggaaagtc   3600

tggagtgttt ccctgttaaa ttgaataact tgatccacac acttgcacaa atgtcagcca   3660

taagccctgc caaatctact tcacagactt ttcctcagga atcctgtttg ctgagtacaa   3720

ctaggtcgat tgaaagagca acaattttag ggttcagcaa gaaatccagt aatctgtatc   3780

tgatccaggt gacacacagc aacaacgaaa caagcctgac agaaaaatca tttgagcagt   3840

tttcaaaact tcacagccaa cttcagaagc agtttgcatc actgactctc ccagagtttc   3900

ctcattggtg gcacctacct tttacaaatt cagatcacag aagattcaga gatctaaatc   3960

attacatgga acagatatta aatgtatcac atgaagttac aaacagtgat tgtgtactta   4020

gctttttcct ctctgaggct gtgcaacaaa cagttgaaga atcatcacct gtgtacctag   4080

gtgagaagtt tccagacaag aagcctaagg tgcagttagt catatcctac gaggatgtga   4140

agctgaccat actagtgaaa cacatgaaaa acattcatct cccagatggc tctgcgccca   4200

gtgcacatgt tgaattttat cttttaccat atcccagtga agttcgtagg aggaaaacaa   4260

aatctgttcc aaaatgtacg gaccccactt acaatgaaat tgtagtatat gatgaagtca   4320

cagagctcca aggacatgtc ttaatgctta ttgtgaagag taaaactgta tttgtgggag   4380

caattaacat ccgactctgt agtgtcccac tcgataaaga aaaatggtat ccattaggaa   4440

acagtataat ttgaccattg ctatgaacat atgcattatt cattaactac ttgtattttt   4500

ttcacttctg ggcctctgaa tcacataagt aaggcatctt tgttgtcaaa gacagcacag   4560

ggtattaagg acacagaaaa aaaatcagaa ttagtctttt gtgttgttta ttttctacct   4620

gtgctttcat tgttttttca taatcttttc tccttcagtg gagtactgat tgcatgaaat   4680

ttgatgtgta aaataataaa agacctttat taaatcattt taatatattt taaattaaac   4740

ataggtttac atttgtttta attgtgtgcc tacagttaaa agcagtattt ttaatgtatt   4800

ttataagaaa gacaatcaaa taaacctcat caattaattc aag                     4843


<210>  8043
<211>  1445
<212>  PRT
<213>  Homo sapiens

<400>  8043

Met Ala Tyr Ser Trp Gln Thr Asp Pro Asn Pro Asn Glu Ser His Glu 
1               5                   10                  15


Lys Gln Tyr Glu His Gln Glu Phe Leu Phe Val Asn Gln Pro His Ser 
            20                  25                  30


Ser Ser Gln Val Ser Leu Gly Phe Asp Gln Ile Val Asp Glu Ile Ser 
        35                  40                  45


Gly Lys Ile Pro His Tyr Glu Ser Glu Ile Asp Glu Asn Thr Phe Phe 
    50                  55                  60


Val Pro Thr Ala Pro Lys Trp Asp Ser Thr Gly His Ser Leu Asn Glu 
65                  70                  75                  80


Ala His Gln Ile Ser Leu Asn Glu Phe Thr Ser Lys Ser Arg Glu Leu 
                85                  90                  95


Ser Trp His Gln Val Ser Lys Ala Pro Ala Ile Gly Phe Ser Pro Ser 
            100                 105                 110


Val Leu Pro Lys Pro Gln Asn Thr Asn Lys Glu Cys Ser Trp Gly Ser 
        115                 120                 125


Pro Ile Gly Lys His His Gly Ala Asp Asp Ser Arg Phe Ser Ile Leu 
    130                 135                 140


Ala Pro Ser Phe Thr Ser Leu Asp Lys Ile Asn Leu Glu Lys Glu Leu 
145                 150                 155                 160


Glu Asn Glu Asn His Asn Tyr His Ile Gly Phe Glu Ser Ser Ile Pro 
                165                 170                 175


Pro Thr Asn Ser Ser Phe Ser Ser Asp Phe Met Pro Lys Glu Glu Asn 
            180                 185                 190


Lys Arg Ser Gly His Val Asn Ile Val Glu Pro Ser Leu Met Leu Leu 
        195                 200                 205


Lys Gly Ser Leu Gln Pro Gly Met Trp Glu Ser Thr Trp Gln Lys Asn 
    210                 215                 220


Ile Glu Ser Ile Gly Cys Ser Ile Gln Leu Val Glu Val Pro Gln Ser 
225                 230                 235                 240


Ser Asn Thr Ser Leu Ala Ser Phe Cys Asn Lys Val Lys Lys Ile Arg 
                245                 250                 255


Glu Arg Tyr His Ala Ala Asp Val Asn Phe Asn Ser Gly Lys Ile Trp 
            260                 265                 270


Ser Thr Thr Thr Ala Phe Pro Tyr Gln Leu Phe Ser Lys Thr Lys Phe 
        275                 280                 285


Asn Ile His Ile Phe Ile Asp Asn Ser Thr Gln Pro Leu His Phe Met 
    290                 295                 300


Pro Cys Ala Asn Tyr Leu Val Lys Asp Leu Ile Ala Glu Ile Leu His 
305                 310                 315                 320


Phe Cys Thr Asn Asp Gln Leu Leu Pro Lys Asp His Ile Leu Ser Val 
                325                 330                 335


Cys Gly Ser Glu Glu Phe Leu Gln Asn Asp His Cys Leu Gly Ser His 
            340                 345                 350


Lys Met Phe Gln Lys Asp Lys Ser Val Ile Gln Leu His Leu Gln Lys 
        355                 360                 365


Ser Arg Glu Ala Pro Gly Lys Leu Ser Arg Lys His Glu Glu Asp His 
    370                 375                 380


Ser Gln Phe Tyr Leu Asn Gln Leu Leu Glu Phe Met His Ile Trp Lys 
385                 390                 395                 400


Val Ser Arg Gln Cys Leu Leu Thr Leu Ile Arg Lys Tyr Asp Phe His 
                405                 410                 415


Leu Lys Tyr Leu Leu Lys Thr Gln Glu Asn Val Tyr Asn Ile Ile Glu 
            420                 425                 430


Glu Val Lys Lys Ile Cys Ser Val Leu Gly Cys Val Glu Thr Lys Gln 
        435                 440                 445


Ile Thr Asp Ala Val Asn Glu Leu Ser Leu Ile Leu Gln Arg Lys Gly 
    450                 455                 460


Glu Asn Phe Tyr Gln Ser Ser Glu Thr Ser Ala Lys Gly Leu Ile Glu 
465                 470                 475                 480


Lys Val Thr Thr Glu Leu Ser Thr Ser Ile Tyr Gln Leu Ile Asn Val 
                485                 490                 495


Tyr Cys Asn Ser Phe Tyr Ala Asp Phe Gln Pro Val Asn Val Pro Arg 
            500                 505                 510


Cys Thr Ser Tyr Leu Asn Pro Gly Leu Pro Ser His Leu Ser Phe Thr 
        515                 520                 525


Val Tyr Ala Ala His Asn Ile Pro Glu Thr Trp Val His Arg Ile Asn 
    530                 535                 540


Phe Pro Leu Glu Ile Lys Ser Leu Pro Arg Glu Ser Met Leu Thr Val 
545                 550                 555                 560


Lys Leu Phe Gly Ile Ala Cys Ala Thr Asn Asn Ala Asn Leu Leu Ala 
                565                 570                 575


Trp Thr Cys Leu Pro Leu Phe Pro Lys Glu Lys Ser Ile Leu Gly Ser 
            580                 585                 590


Met Leu Phe Ser Met Thr Leu Gln Ser Glu Pro Pro Val Glu Met Ile 
        595                 600                 605


Thr Pro Gly Val Trp Asp Val Ser Gln Pro Ser Pro Val Thr Leu Gln 
    610                 615                 620


Ile Asp Phe Pro Ala Thr Gly Trp Glu Tyr Met Lys Pro Asp Ser Glu 
625                 630                 635                 640


Glu Asn Arg Ser Asn Leu Glu Glu Pro Leu Lys Glu Cys Ile Lys His 
                645                 650                 655


Ile Ala Arg Leu Ser Gln Lys Gln Thr Pro Leu Leu Leu Ser Glu Glu 
            660                 665                 670


Lys Lys Arg Tyr Leu Trp Phe Tyr Arg Phe Tyr Cys Asn Asn Glu Asn 
        675                 680                 685


Cys Ser Leu Pro Leu Val Leu Gly Ser Ala Pro Gly Trp Asp Glu Arg 
    690                 695                 700


Thr Val Ser Glu Met His Thr Ile Leu Arg Arg Trp Thr Phe Ser Gln 
705                 710                 715                 720


Pro Leu Glu Ala Leu Gly Leu Leu Thr Ser Ser Phe Pro Asp Gln Glu 
                725                 730                 735


Ile Arg Lys Val Ala Val Gln Gln Leu Asp Asn Leu Leu Asn Asp Glu 
            740                 745                 750


Leu Leu Glu Tyr Leu Pro Gln Leu Val Gln Ala Val Lys Phe Glu Trp 
        755                 760                 765


Asn Leu Glu Ser Pro Leu Val Gln Leu Leu Leu His Arg Ser Leu Gln 
    770                 775                 780


Ser Ile Gln Val Ala His Arg Leu Tyr Trp Leu Leu Lys Asn Ala Glu 
785                 790                 795                 800


Asn Glu Ala Tyr Phe Lys Ser Trp Tyr Gln Lys Leu Leu Ala Ala Leu 
                805                 810                 815


Gln Phe Cys Ala Gly Lys Ala Leu Asn Asp Glu Phe Ser Lys Glu Gln 
            820                 825                 830


Lys Leu Ile Lys Ile Leu Gly Asp Ile Gly Glu Arg Val Lys Ser Ala 
        835                 840                 845


Ser Asp His Gln Arg Gln Glu Val Leu Lys Lys Glu Ile Gly Arg Leu 
    850                 855                 860


Glu Glu Phe Phe Gln Asp Val Asn Thr Cys His Leu Pro Leu Asn Pro 
865                 870                 875                 880


Ala Leu Cys Ile Lys Gly Ile Asp His Asp Ala Cys Ser Tyr Phe Thr 
                885                 890                 895


Ser Asn Ala Leu Pro Leu Lys Ile Thr Phe Ile Asn Ala Asn Pro Met 
            900                 905                 910


Gly Lys Asn Ile Ser Ile Ile Phe Lys Ala Gly Asp Asp Leu Arg Gln 
        915                 920                 925


Asp Met Leu Val Leu Gln Leu Ile Gln Val Met Asp Asn Ile Trp Leu 
    930                 935                 940


Gln Glu Gly Leu Asp Met Gln Met Ile Ile Tyr Arg Cys Leu Ser Thr 
945                 950                 955                 960


Gly Lys Asp Gln Gly Leu Val Gln Met Val Pro Asp Ala Val Thr Leu 
                965                 970                 975


Ala Lys Ile His Arg His Ser Gly Leu Ile Gly Pro Leu Lys Glu Asn 
            980                 985                 990


Thr Ile Lys Lys Trp Phe Ser Gln His Asn His Leu Lys Ala Asp Tyr 
        995                 1000                1005


Glu Lys Ala Leu Arg Asn Phe Phe Tyr Ser Cys Ala Gly Trp Cys Val 
    1010                1015                1020


Val Thr Phe Ile Leu Gly Val Cys Asp Arg His Asn Asp Asn Ile Met 
1025                1030                1035                1040


Leu Thr Lys Ser Gly His Met Phe His Ile Asp Phe Gly Lys Phe Leu 
                1045                1050                1055


Gly His Ala Gln Thr Phe Gly Gly Ile Lys Arg Asp Arg Ala Pro Phe 
            1060                1065                1070


Ile Phe Thr Ser Glu Met Glu Tyr Phe Ile Thr Glu Gly Gly Lys Asn 
        1075                1080                1085


Pro Gln His Phe Gln Asp Phe Val Glu Leu Cys Cys Arg Ala Tyr Asn 
    1090                1095                1100


Ile Ile Arg Lys His Ser Gln Leu Leu Leu Asn Leu Leu Glu Met Met 
1105                1110                1115                1120


Leu Tyr Ala Gly Leu Pro Glu Leu Ser Gly Ile Gln Asp Leu Lys Tyr 
                1125                1130                1135


Val Tyr Asn Asn Leu Arg Pro Gln Asp Thr Asp Leu Glu Ala Thr Ser 
            1140                1145                1150


His Phe Thr Lys Lys Ile Lys Glu Ser Leu Glu Cys Phe Pro Val Lys 
        1155                1160                1165


Leu Asn Asn Leu Ile His Thr Leu Ala Gln Met Ser Ala Ile Ser Pro 
    1170                1175                1180


Ala Lys Ser Thr Ser Gln Thr Phe Pro Gln Glu Ser Cys Leu Leu Ser 
1185                1190                1195                1200


Thr Thr Arg Ser Ile Glu Arg Ala Thr Ile Leu Gly Phe Ser Lys Lys 
                1205                1210                1215


Ser Ser Asn Leu Tyr Leu Ile Gln Val Thr His Ser Asn Asn Glu Thr 
            1220                1225                1230


Ser Leu Thr Glu Lys Ser Phe Glu Gln Phe Ser Lys Leu His Ser Gln 
        1235                1240                1245


Leu Gln Lys Gln Phe Ala Ser Leu Thr Leu Pro Glu Phe Pro His Trp 
    1250                1255                1260


Trp His Leu Pro Phe Thr Asn Ser Asp His Arg Arg Phe Arg Asp Leu 
1265                1270                1275                1280


Asn His Tyr Met Glu Gln Ile Leu Asn Val Ser His Glu Val Thr Asn 
                1285                1290                1295


Ser Asp Cys Val Leu Ser Phe Phe Leu Ser Glu Ala Val Gln Gln Thr 
            1300                1305                1310


Val Glu Glu Ser Ser Pro Val Tyr Leu Gly Glu Lys Phe Pro Asp Lys 
        1315                1320                1325


Lys Pro Lys Val Gln Leu Val Ile Ser Tyr Glu Asp Val Lys Leu Thr 
    1330                1335                1340


Ile Leu Val Lys His Met Lys Asn Ile His Leu Pro Asp Gly Ser Ala 
1345                1350                1355                1360


Pro Ser Ala His Val Glu Phe Tyr Leu Leu Pro Tyr Pro Ser Glu Val 
                1365                1370                1375


Arg Arg Arg Lys Thr Lys Ser Val Pro Lys Cys Thr Asp Pro Thr Tyr 
            1380                1385                1390


Asn Glu Ile Val Val Tyr Asp Glu Val Thr Glu Leu Gln Gly His Val 
        1395                1400                1405


Leu Met Leu Ile Val Lys Ser Lys Thr Val Phe Val Gly Ala Ile Asn 
    1410                1415                1420


Ile Arg Leu Cys Ser Val Pro Leu Asp Lys Glu Lys Trp Tyr Pro Leu 
1425                1430                1435                1440


Gly Asn Ser Ile Ile 
                1445


<210>  8044
<211>  307
<212>  DNA
<213>  Homo sapiens

<400>  8044
atcaattttc cccttgaaat aaagtcactt ccaagggaat ccatgctcac tgtaaaactg     60

tttgggattg cctgtgcaac caacaatgca aatttactgg cgtggacttg tcttccactg    120

tttccaaaag agagcagcta tacaagtgtc tttccttctc atgagtgagt ttccttaaag    180

ttttacctgc agtatttgta agatctacca ttttttgtag aatatttcta gctagtcact    240

gaaaataaaa aaaggttaag tccattttac tctcccatca tgtaacacac tacttgcaca    300

tatcaat                                                              307


<210>  8045
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8045

Met Leu Thr Val Lys Leu Phe Gly Ile Ala Cys Ala Thr Asn Asn Ala 
1               5                   10                  15


Asn Leu Leu Ala Trp Thr Cys Leu Pro Leu Phe Pro Lys Glu Ser Ser 
            20                  25                  30


Tyr Thr Ser Val Phe Pro Ser His Glu 
        35                  40


<210>  8046
<211>  704
<212>  DNA
<213>  Homo sapiens

<400>  8046
aaacatggag acagcgggct ctggtactgg gcagccggcc tctctgctgg aggctcccgg     60

gtccacggat gaccggcttt tcctggttaa aggtggaatt ttccttggta ctgttgctgc    120

agcaggaacg ctagctggat ttattacaac attatcattg gctaaaaaga aaagccctga    180

atggttcaat aagggaagta tggtcacgac tgcattaccg gaaagcgggt cttcccttgc    240

cttgcgagct ctgggctgcg gctcactgta tgcatggtgt ggggttggtg tgattagctt    300

ctcagtctgg aaagctttag gggttcacag tgacatgtaa gagatatcct cattttaatt    360

gaaggctaca tcaccaactt tctacccgag aagtcgtttt tcttcgggac ccacaatcaa    420

aggctttcct ccggcatgag aaaggagtaa cattcccgcc tggtgagttt ttagtgctgg    480

agtgactccc agccggcccc taccccgctc aagctcctgc tgactgtccc agtgtgggtc    540

ctggccaaga ctggcaccaa ggcagtggga tcctttataa gtaggcctcc agcgccatac    600

accagaaagc aggagcccac ttctgggaca ctgggagagg gtgcaggcag ccaccagtac    660

gcaaagcaca gtgccctatc cttcccggca gggtcacagt tcag                     704


<210>  8047
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  8047

Met Glu Thr Ala Gly Ser Gly Thr Gly Gln Pro Ala Ser Leu Leu Glu 
1               5                   10                  15


Ala Pro Gly Ser Thr Asp Asp Arg Leu Phe Leu Val Lys Gly Gly Ile 
            20                  25                  30


Phe Leu Gly Thr Val Ala Ala Ala Gly Thr Leu Ala Gly Phe Ile Thr 
        35                  40                  45


Thr Leu Ser Leu Ala Lys Lys Lys Ser Pro Glu Trp Phe Asn Lys Gly 
    50                  55                  60


Ser Met Val Thr Thr Ala Leu Pro Glu Ser Gly Ser Ser Leu Ala Leu 
65                  70                  75                  80


Arg Ala Leu Gly Cys Gly Ser Leu Tyr Ala Trp Cys Gly Val Gly Val 
                85                  90                  95


Ile Ser Phe Ser Val Trp Lys Ala Leu Gly Val His Ser Asp Met 
            100                 105                 110


<210>  8048
<211>  2729
<212>  DNA
<213>  Homo sapiens

<400>  8048
ctcttcacct ccgtgagcaa gatggcgact gtgaagagtg agcttattga gtgcttcact     60

tccgaggagc cctttcatca cagaaaggtc tccatcacag gaactggatc agtgggcatg    120

gcctgcgcta ccagcatctt attaaaaggc ttgagtgatg aacttgcctt tgtggatctt    180

gatgaaggca aactgaaagg tgagacaatg gatcttcaac atgacagccc tttcatgaaa    240

atgtcaaata ttgtttgtag caaagattac cttgtcacag caaaccccca tctagtgatt    300

atcacagcag gtgcacgccg agaaaaggga gaaatgcgct ttaatttagt ccggcaaaat    360

gtggccatct tcaagttaat gatttccagt attgtccagc agagccccct ctgcaaacta    420

attattgttt ccaatccagt agatatctta acttacgtag cctggaagtt gagtgcattt    480

cccaaaaacc gtgttattgg aagcggctgt aatctggata ctgttcgttt tcaattcttc    540

attggacaaa agcttggtat ccactctgaa agctgccgtg gatggatcct cggagagcat    600

ggagactcaa gtgttcctgt gtggagtgga atgaacatag ctggtgtcct tttgaaggat    660

ctgaactctg atataggaac tgataaagat cctgagaaat ggaaaaatgt ccacaaagaa    720

gtgattgcta gtgcctatga gattattgaa atgaaaagtt ctacttcgtg ggccattggc    780

ctatctggag ctgatttaac agaaagtatt ttgaagaatc ttaggagaaa acatccagtt    840

tccaccataa ttaagggcct ctacggaata aatgaagaag tcttcctcag tattccttct    900

ttggagagaa gggtattacc aaccttataa agagaaagct gacccctgaa gaggaggccc    960

atctgaaaaa gatgactttc ctttttattt agtcttccag ctcttttatt tagcatccag   1020

gtgctggatg atacttattt acaattccta aagaaagtgt ttttggtaat gctgatatag   1080

cagtacttac cttgttatat atatgtagtt ggcatttggt tcctaaaaag taggatgtag   1140

gtatttactg tgtttgagaa attctgattc ttttcactag atatatgcta tttattcttg   1200

ctggcttata cctatgttca tttatatgct gtaaaaaagt ggtaatttac aatgtaaaaa   1260

taaaagtatg catatacaaa atttctcttt tttctaactt gctcttcaga cttaatgctc   1320

agtattacct tcctcactat gagtttgtct cccctagaag atagtctatg tattccattt   1380

ggctgtggat ctgattctgc ttggggcatg tatttctctt gaatacttga ataccatggg   1440

acccacccat gttttctggg actcaggcat aaggcaatca cctcaatttt ctatgtccat   1500

gtaatgactc ttgtgctggt gttatctaac atgttaacta gattgtagtt gtagttctct   1560

gcatgtaagg atcaatgctt ttttttctgc tgattcccca acaaccttat ataatgttga   1620

gttcctataa gatgcttaga aactagttgt taatttgtac attcccactt tttggatctt   1680

taccaagctt atcttttgtt ggaggatttt gtaaaaacaa aaaggggaag agtagacact   1740

gctgaaggaa agaacttaaa agtcaggaac tgccttggtt tcccctttta ttttcttcct   1800

cttgcttttg ttatctcctc tttctaatat agcaatatga gtgtatggct accacatata   1860

tttgtttaaa tttaacttaa aatatccatt ctagataatc tgcctttagc ccttttctat   1920

cagggtacta tattttatca ttaattaatt ccttataatt aacttcattt atttcttatt   1980

aatctcataa tggacaagga gtaccagtgc ctggttgaat aaagagggga atcactttgt   2040

tgtcagaaca gaaactcatt caaaccagct caggtcagaa acaaaaagtg gggaatgtat   2100

tgaatgtctg atggtatctc taataactgt agagtaataa ttatagagat ctgtcatttg   2160

gtactggatc caggacccag aaaatttgaa tccaaggtta tttgctttgt ttttttcaga   2220

agagttgatc tcttggctct gctcctattg gtacatcaac tttatttttc ctgggtctta   2280

ctgtagatta tcttactgtg ctccggcccg cacatgttgg tcccagcctc tgcgtttcca   2340

gatctcctaa ctcaaacact catcagaaat taagtgcagt ctagtttctg tgttccaatt   2400

ctaaattcca agaagagatt ctgattgtcc agctttgcta agatacagac cccccatcct   2460

gtcagcaggg gttagggtgt agaagagtca tgtcctacaa acatgggtac aaatatgggc   2520

atcagcacgg gggaggtgct tacccctgaa agtccctaag tgttggcgtg aacagtttcg   2580

caatatatac tggctgattt tactatggca ggctcacaaa gtttatacag aatagacctt   2640

tccaatctcc ttgatttctt tgttttgaaa tgtggctgat gtctgaatac agtatccaac   2700

aaaataatta aagtgctgtt tggagattt                                     2729


<210>  8049
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  8049

Met Leu Phe Ile Leu Ala Gly Leu Tyr Leu Cys Ser Phe Ile Cys Cys 
1               5                   10                  15


Lys Lys Val Val Ile Tyr Asn Val Lys Ile Lys Val Cys Ile Tyr Lys 
            20                  25                  30


Ile Ser Leu Phe Ser Asn Leu Leu Phe Arg Leu Asn Ala Gln Tyr Tyr 
        35                  40                  45


Leu Pro His Tyr Glu Phe Val Ser Pro Arg Arg 
    50                  55


<210>  8050
<211>  532
<212>  DNA
<213>  Homo sapiens

<400>  8050
ctgatgagtg tttgagttag gagatctgga aacgcagagg ctgggaccaa catgtgcggg     60

ccggagcaca catataaatg aacataggta taagccagca agaataaata gcatatatct    120

agtgaaaaga atcagaattt ctcaaacaca gtaaatacct acatcctact ttttaggaac    180

caaatgccaa ctacatatat ataacaagtg tttttgcact ctttttcaga tgggcctcct    240

cttcaggggt cagctttctc tttataaggt tggtaatacc cttctctcca aagaaggaat    300

actgaggaag acttcttcat ttattccgta gaggccctta attatggtgg aaactggatg    360

ttttctccta agattcttca aaatactttc tgttaaatca gctccagata ggccaatggc    420

ccacgaagta gaacttttca tttcaataat ctcataggca ctagcaatca cttctttgtg    480

gacatttttc catttctcag gatctttatc agttcctata tcagagttca ga            532


<210>  8051
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  8051

Met Val Glu Thr Gly Cys Phe Leu Leu Arg Phe Phe Lys Ile Leu Ser 
1               5                   10                  15


Val Lys Ser Ala Pro Asp Arg Pro Met Ala His Glu Val Glu Leu Phe 
            20                  25                  30


Ile Ser Ile Ile Ser 
        35


<210>  8052
<211>  1062
<212>  DNA
<213>  Homo sapiens

<400>  8052
gctttccgcg ctacctgcag aggggtccat acggcgctgt tctggattcc cgttgtaact     60

taaagggaaa ctttcacaat gtccggagcc cttgatgtcc tgcaaatgag ggaggaggat    120

gtccttaagt tccttgcagc aggaacccac ttaggtggca ccaatcttga cttccagatg    180

gaacagtaca tctatgaaag gaaaagtgat ggcatctata tcataaatct gaagaggacc    240

tgggagaagc ttctgctggc agctcatgct attgttgcca ttgaaaaccc tgctgatgtc    300

agtgttatat cctccaggaa tactggccag acggctgtgc tgaagtttgc tgctgccact    360

ggagccactc caattgctgg gcgcttcact cctggaacct tcactaacca gatccaggca    420

gccttccggg agccacggct tcttgtggtt actgacccca gggctgacca ccagcctctc    480

acggaggcat cttatgttaa cctacctacc attgcgctgt gtaacacaga ttctcctctg    540

cgctatgtgg acattgccat cccatgcaac aacaagggag cttactcagt gggtttgatg    600

tggtggatgc tggctcggga agttctgtgc atgcttggca ccatttcctg tgaacaccca    660

tgggaggtca tgcctgatct gtacttctac agagatcctg aagagattga aaaagaagag    720

caggctgctg ctgaaaaggc agtgaccaag gaggaatttc agggtgaatg gactgctcca    780

gctcctgagt tcactgctat tcagcctgag gttgcagact ggtctgaagg tgtacaggtg    840

ccctctgtgc ctattcagca attccctact gaagactgga gctctcagcc tgccatggaa    900

gactggtctg cagctcccac tgctcaggcc actgaatggg taggagcaac cactgactgg    960

tcttaagctg ttcttgcata ggctcttaag cagcatggaa aaatggttga tggaaaataa   1020

gcatcagttt ctaaaaaaaa aaaaagaata atttgacttc tt                      1062


<210>  8053
<211>  295
<212>  PRT
<213>  Homo sapiens

<400>  8053

Met Ser Gly Ala Leu Asp Val Leu Gln Met Arg Glu Glu Asp Val Leu 
1               5                   10                  15


Lys Phe Leu Ala Ala Gly Thr His Leu Gly Gly Thr Asn Leu Asp Phe 
            20                  25                  30


Gln Met Glu Gln Tyr Ile Tyr Glu Arg Lys Ser Asp Gly Ile Tyr Ile 
        35                  40                  45


Ile Asn Leu Lys Arg Thr Trp Glu Lys Leu Leu Leu Ala Ala His Ala 
    50                  55                  60


Ile Val Ala Ile Glu Asn Pro Ala Asp Val Ser Val Ile Ser Ser Arg 
65                  70                  75                  80


Asn Thr Gly Gln Thr Ala Val Leu Lys Phe Ala Ala Ala Thr Gly Ala 
                85                  90                  95


Thr Pro Ile Ala Gly Arg Phe Thr Pro Gly Thr Phe Thr Asn Gln Ile 
            100                 105                 110


Gln Ala Ala Phe Arg Glu Pro Arg Leu Leu Val Val Thr Asp Pro Arg 
        115                 120                 125


Ala Asp His Gln Pro Leu Thr Glu Ala Ser Tyr Val Asn Leu Pro Thr 
    130                 135                 140


Ile Ala Leu Cys Asn Thr Asp Ser Pro Leu Arg Tyr Val Asp Ile Ala 
145                 150                 155                 160


Ile Pro Cys Asn Asn Lys Gly Ala Tyr Ser Val Gly Leu Met Trp Trp 
                165                 170                 175


Met Leu Ala Arg Glu Val Leu Cys Met Leu Gly Thr Ile Ser Cys Glu 
            180                 185                 190


His Pro Trp Glu Val Met Pro Asp Leu Tyr Phe Tyr Arg Asp Pro Glu 
        195                 200                 205


Glu Ile Glu Lys Glu Glu Gln Ala Ala Ala Glu Lys Ala Val Thr Lys 
    210                 215                 220


Glu Glu Phe Gln Gly Glu Trp Thr Ala Pro Ala Pro Glu Phe Thr Ala 
225                 230                 235                 240


Ile Gln Pro Glu Val Ala Asp Trp Ser Glu Gly Val Gln Val Pro Ser 
                245                 250                 255


Val Pro Ile Gln Gln Phe Pro Thr Glu Asp Trp Ser Ser Gln Pro Ala 
            260                 265                 270


Met Glu Asp Trp Ser Ala Ala Pro Thr Ala Gln Ala Thr Glu Trp Val 
        275                 280                 285


Gly Ala Thr Thr Asp Trp Ser 
    290                 295


<210>  8054
<211>  2107
<212>  DNA
<213>  Homo sapiens

<400>  8054
gcgaggctga acgcctgacg tcaaggcgac atcgccaaac ctcgcccaga ttcaggcgtg     60

taaaccagcc ggagcggcgc ggcagcggca ggaccgccgt ggcgcctaga gtagcgaccc    120

ggggggagcg cggggcgacg ctggctgcag ggacccggtg acagcgtgag aggtactagg    180

ttttgacaag cttgcatcat gcgtgagtat aagctagtcg ttcttggctc aggaggcgtt    240

ggaaagtctg ctttgactgt acaatttgtt caaggaattt ttgtagaaaa atacgatcct    300

acgatagaag attcttatag aaagcaagtt gaagtagatg cacaacagtg tatgcttgaa    360

atcttggata ctgcaggaac ggagcaattt acagcaatga gggatttata catgaaaaat    420

ggacaaggat ttgcattagt ttattccatc acagcacagt ccacatttaa cgatttacaa    480

gacctgagag aacagattct tcgagttaaa gacactgatg atgttccaat gattcttgtt    540

ggtaataagt gtgacttgga agatgaaaga gttgtaggga aggaacaagg tcaaaatcta    600

gcaagacaat ggaacaactg tgcattctta gaatcttctg caaaatcaaa aataaatgtt    660

aatgagatct tttatgacct agtgcggcaa attaacagaa aaactccagt gcctgggaag    720

gctcgcaaaa agtcatcatg tcagctgctt taatatacta aatgcattgt agctctgagc    780

caggtctgaa gaactgttgc ccaattcaac agtgccagca ttccaacttt gttaaaccta    840

ccaacatctt aaatggactt tcctgtggtg gtacccttta agaggcggat gaaagctact    900

atatcagttt gcacattcta atcactttcc agtatcacaa gagagatttt tacttatata    960

atagtcctag agtttgcagc tggtaaaacc agaggctaca tccagtatta ctgctaagag   1020

acattcttca tccaccaatg ttgtacatgt atgaaaatgg tgtactgtat actttaacat   1080

gccccatact ttgtattgga gagtacaata atgtaaatcc taaaagcacc actattttag   1140

cataataaaa gaaagtccaa agagctccta tatagactac tccagataac ttcgcttctt   1200

tgatacttgt agcttattgt aatttttttt aagaaattca aggtcattat tattgtacaa   1260

aataagcgct ttgattaaca cagctatata gtttttttaa tttttaaaaa acctgtggag   1320

acggtgatct tgtctttaaa acatgatagt cctttcagta taatgtctta gattaaagac   1380

gttgccttta atatctgttg ggaaggaaat gtccagactt ttcaaatctc ttattatatg   1440

tttccttttt ttgtttacat agggaacaat gtttatagtc gtgtgtacag tgggggtcta   1500

caacaagaag tgtatatttt caaacaattt tttaatgatt taacaatttt tgtaaatcat   1560

tttcaggctt ctgcagctgt agattctcac tgtgaatccc ttgcttgctc atgcataagt   1620

gtatttgcaa taccaaatat acaggtttag tatttttgcc tgttagtgat tgtttcacat   1680

gtgtaacgtt ttggttgaga tgttaaatgg tggacgagta ctgtggatgt gaatgtggga   1740

agtaatttta atcatatgta attggtcaca aggcctaatt tgcagtaact attgctgttt   1800

tatttaacaa tgccttgttg ctttgtatgc attaatgttt ggatgtaaag attgtgtgtc   1860

tatccaacag ggagccacag tatttaaatt gaccaaccta atgttacaac tactttgagg   1920

tggccaaatg taaactaaaa gccttaatta aagtggtgca attttgtata acttagcatc   1980

agtagttcaa taaatttgga ttgccatgca agggcttgca ttataattac ttgccacttg   2040

aatgtgtttt gtgtaatgtt ttaacagtgc tagtaaataa atacgggttt accctggttt   2100

taattgt                                                             2107


<210>  8055
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  8055

Met Arg Glu Tyr Lys Leu Val Val Leu Gly Ser Gly Gly Val Gly Lys 
1               5                   10                  15


Ser Ala Leu Thr Val Gln Phe Val Gln Gly Ile Phe Val Glu Lys Tyr 
            20                  25                  30


Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Glu Val Asp Ala 
        35                  40                  45


Gln Gln Cys Met Leu Glu Ile Leu Asp Thr Ala Gly Thr Glu Gln Phe 
    50                  55                  60


Thr Ala Met Arg Asp Leu Tyr Met Lys Asn Gly Gln Gly Phe Ala Leu 
65                  70                  75                  80


Val Tyr Ser Ile Thr Ala Gln Ser Thr Phe Asn Asp Leu Gln Asp Leu 
                85                  90                  95


Arg Glu Gln Ile Leu Arg Val Lys Asp Thr Asp Asp Val Pro Met Ile 
            100                 105                 110


Leu Val Gly Asn Lys Cys Asp Leu Glu Asp Glu Arg Val Val Gly Lys 
        115                 120                 125


Glu Gln Gly Gln Asn Leu Ala Arg Gln Trp Asn Asn Cys Ala Phe Leu 
    130                 135                 140


Glu Ser Ser Ala Lys Ser Lys Ile Asn Val Asn Glu Ile Phe Tyr Asp 
145                 150                 155                 160


Leu Val Arg Gln Ile Asn Arg Lys Thr Pro Val Pro Gly Lys Ala Arg 
                165                 170                 175


Lys Lys Ser Ser Cys Gln Leu Leu 
            180


<210>  8056
<211>  582
<212>  DNA
<213>  Homo sapiens

<400>  8056
gacatcgcca aacctcgccc agattcaggc gtgtaaacca gccggagcgg cgcggcagcg     60

gcaggaccgc cgtggcgcct agagtagcga cccgggggga gcgcggggcg acgctggctg    120

cagggacccg gtgacagcgt gagaggtact aggttttgac aagcttgcat catgcgtgag    180

tataagctag tcgttcttgg ctcaggaggc gttggaaagt ctgctttggt aagtcattct    240

tactttacct aagcctttca ctccaagacg ttctttttct gttgagtttt aggttttgat    300

gatttgtctt tgttaagata aaattcctta atgactttag aagcaatata atatttttct    360

tgtaatttta ttcaactttt aattatatct gggtggatca tattctctct ggaacattga    420

ctccagaatg acacgagtta tgctggaata caatttgagc taagcacaga gattgagagc    480

gtacaaatac atgtcttttt gcattcgcat ttcagagcca gataggaata aattttggtc    540

tttttattta tttatttttt tgaaacaggg tctcactctg tt                       582


<210>  8057
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  8057

His Arg Gln Thr Ser Pro Arg Phe Arg Arg Val Asn Gln Pro Glu Arg 
1               5                   10                  15


Arg Gly Ser Gly Arg Thr Ala Val Ala Pro Arg Val Ala Thr Arg Gly 
            20                  25                  30


Glu Arg Gly Ala Thr Leu Ala Ala Gly Thr Arg 
        35                  40


<210>  8058
<211>  1942
<212>  DNA
<213>  Homo sapiens

<400>  8058
gacatcgcca aacctcgccc agattcaggc gtgtaaacca gccggagcgg cgcggcagcg     60

gcaggaccgc cgtggcgcct agagtagcga cccgggggga gcgcggggcg acgctggctg    120

cagggacccg gtgacagcgt gagaggtact aggttttgac aagcttgcat catgcgtgag    180

tataagctag tcgttcttgg ctcaggaggc gttggaaagt ctgctttgac tgtacaattt    240

gttcaaggaa tttttgtaga aaaatacgat cctacgatag aagattctta tagaaagcaa    300

gttgaagtag atgcacaaca gtgtatgctt gaaatcttgg atactgcagg aacggagcaa    360

tttacagcaa tgagggattt atacatgaaa aatggacaag gatttgcatt agtttattcc    420

atcacagcac agtccacatt taacgattta caagacctga gagaacagat tcttcgagtt    480

aaagacactg atgatgttcc aatgattctt gttggtaata agtgtgactt ggaagatgaa    540

agagttgtag ggaaggaaca aggtcaaaat ctagcaagac aatggaacaa ctgtgcattc    600

ttagaatctt ctgcaaaatc aaaaataaat gttaatgaga tcttttatga cctagtgcgg    660

caaattaaca gaaaaactcc agtgcctggg aaggctcgca aaaagtcatc atgtcagctg    720

ctttaatata ctaaatgcat tgtagctctg agccaggtct gaagaactgt tgcccaattc    780

aacagtgcca gcattccaac tttgttaaac ctaccaacat cttaaatgga ctttcctgtg    840

gtggtaccct ttaagaggcg gatgaaagct actatatcag tttgcacatt ctaatcactt    900

tccagtatca caagagagat ttttacttat ataatagtcc tagagtttgc agctggtaaa    960

accagaggct acatccagta ttactgctaa gagacattct tcatccacca atgttgtaca   1020

tgtatgaaaa tggtgtactg tatactttaa catgccccat actttgtatt ggagagtaca   1080

ataatgtaaa tcctaaaagc accactattt tagcataata aaagaaagtc caaagagctc   1140

ctatatagac tactccagat aacttcgctt ctttgatact tgtagcttat tgtaattttt   1200

tttaagaaat tcaaggtcat tattattgta caaaataagc gctttgatta acacagctat   1260

atagtttttt taatttttaa aaaacctgtg gagacggtga tcttgtcttt aaaacatgat   1320

agtcctttca gtataatgtc ttagattaaa gacgttgcct ttaatatctg ttgggaagga   1380

aatgtccaga cttttcaaat ctcttattat atgtttcctt tttttgttta catagggaac   1440

aatgtttata gtcgtgtgta cagtgggggt ctacaacaag aagtgtatat tttcaaacaa   1500

ttttttaatg atttaacaat ttttgtaaat cattttcagg cttctgcagc tgtagattct   1560

cactgtgaat cccttgcttg ctcatgcata agtgtatttg caataccaaa tatacaggtt   1620

tagtattttt gcctgttagt gattgtttca catgtgtaac gttttggttg agatgttaaa   1680

tggtggacga gtactgtgga tgtgaatgtg ggaagtaatt ttaatcatat gtaattggtc   1740

acaaggccta atttgcagta actattgctg ttttatttaa caatgccttg ttgctttgta   1800

tgcattaatg tttggatgta aagattgtgt gtctatccaa cagggagcca cagtatttaa   1860

attgaccaac ctaatgttac aactactttg aggtggccaa atgtaaacta aaagccttaa   1920

ttaaagtggt gcaattttgt at                                            1942


<210>  8059
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  8059

Met Arg Glu Tyr Lys Leu Val Val Leu Gly Ser Gly Gly Val Gly Lys 
1               5                   10                  15


Ser Ala Leu Thr Val Gln Phe Val Gln Gly Ile Phe Val Glu Lys Tyr 
            20                  25                  30


Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Glu Val Asp Ala 
        35                  40                  45


Gln Gln Cys Met Leu Glu Ile Leu Asp Thr Ala Gly Thr Glu Gln Phe 
    50                  55                  60


Thr Ala Met Arg Asp Leu Tyr Met Lys Asn Gly Gln Gly Phe Ala Leu 
65                  70                  75                  80


Val Tyr Ser Ile Thr Ala Gln Ser Thr Phe Asn Asp Leu Gln Asp Leu 
                85                  90                  95


Arg Glu Gln Ile Leu Arg Val Lys Asp Thr Asp Asp Val Pro Met Ile 
            100                 105                 110


Leu Val Gly Asn Lys Cys Asp Leu Glu Asp Glu Arg Val Val Gly Lys 
        115                 120                 125


Glu Gln Gly Gln Asn Leu Ala Arg Gln Trp Asn Asn Cys Ala Phe Leu 
    130                 135                 140


Glu Ser Ser Ala Lys Ser Lys Ile Asn Val Asn Glu Ile Phe Tyr Asp 
145                 150                 155                 160


Leu Val Arg Gln Ile Asn Arg Lys Thr Pro Val Pro Gly Lys Ala Arg 
                165                 170                 175


Lys Lys Ser Ser Cys Gln Leu Leu 
            180


<210>  8060
<211>  2013
<212>  DNA
<213>  Homo sapiens

<400>  8060
gacatcgcca aacctcgccc agattcaggc gtgtaaacca gccggagcgg cgcggcagcg     60

gcaggaccgc cgtggcgcct agagtagcga cccgggggga gcgcggggcg acgctggctg    120

cagggacccg gtgacagcgt gagaggtact aggttttgac aagcttgcat catgcgtgag    180

tataagctag tcgttcttgg ctcaggaggc gttggaaagt ctgctttgac tgtacaattt    240

gttcaaggaa tttttgtaga aaaatacgat cctacgatag aagattctta tagaaagcaa    300

gttgaagtag atgcacaaca gtgtatgctt gaaatcttgg atactgcagg aacggagcaa    360

tttacagcaa tgagggattt atacatgaaa aatggacaag gatttgcatt agtttattcc    420

atcacagcac agtccacatt taacgattta caagacctga gagaacagat tcttcgagtt    480

aaagacactg atgatgttcc aatgattctt gttggtaata agtgtgactt ggaagatgaa    540

agagttgtag ggaaggaaca aggtcaaaat ctagcaagac aatggaacaa ctgtgcattc    600

ttagaatctt ctgcaaaatc aaaaataaat gttaatgaga tcttttatga cctagtgcgg    660

caaattaaca gaaaaactcc agtgcctggg aaggctcgca aaaagtcatc atgtcagctg    720

ctttaatata ctaaatgcat tgtagctctg agccaggtct gaagaactgt tgcccaattc    780

aacagtgcca gcattccaac tttgttaaac ctaccaacat cttaaatgga ctttcctgtg    840

gtggtaccct ttaagaggcg gatgaaagct actatatcag tttgcacatt ctaatcactt    900

tccagtatca caagagagat ttttacttat ataatagtcc tagagtttgc agctggtaaa    960

accagaggct acatccagta ttactgctaa gagacattct tcatccacca atgttgtaca   1020

tgtatgaaaa tggtgtactg tatactttaa catgccccat actttgtatt ggagagtaca   1080

ataatgtaaa tcctaaaagc accactattt tagcataata aaagaaagtc caaagagctc   1140

ctatatagac tactccagat aacttcgctt ctttgatact tgtagcttat tgtaattttt   1200

tttaagaaat tcaaggtcat tattattgta caaaataagc gctttgatta acacagctat   1260

atagtttttt taatttttaa aaaacctgtg gagacggtga tcttgtcttt aaaacatgat   1320

agtcctttca gtataatgtc ttagattaaa gacgttgcct ttaatatctg ttgggaagga   1380

aatgtccaga cttttcaaat ctcttattat atgtttcctt tttttgttta catagggaac   1440

aatgtttata gtcgtgtgta cagtgggggt ctacaacaag aagtgtatat tttcaaacaa   1500

ttttttaatg atttaacaat ttttgtaaat cattttcagg cttctgcagc tgtagattct   1560

cactgtgaat cccttgcttg ctcatgcata agtgtatttg caataccaaa tatacaggtt   1620

tagtattttt gcctgttagt gattgtttca catgtgtaac gttttggttg agatgttaaa   1680

tggtggacga gtactgtgga tgtgaatgtg ggaagtaatt ttaatcatat gtaattggtc   1740

acaaggccta atttgcagta actattgctg ttttatttaa caatgccttg ttgctttgta   1800

tgcattaatg tttggatgta aagattgtgt gtctatccaa cagggagcca cagtatttaa   1860

attgaccaac ctaatgttac aactactttg aggtggccaa atgtaaacta aaagccttaa   1920

ttaaagtggt gcaattttgt ataacttagc atcagtagtt caataaattt ggattgccat   1980

gcaagggctt gcattataat tacttgccac ttg                                2013


<210>  8061
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  8061

Met Arg Glu Tyr Lys Leu Val Val Leu Gly Ser Gly Gly Val Gly Lys 
1               5                   10                  15


Ser Ala Leu Thr Val Gln Phe Val Gln Gly Ile Phe Val Glu Lys Tyr 
            20                  25                  30


Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Glu Val Asp Ala 
        35                  40                  45


Gln Gln Cys Met Leu Glu Ile Leu Asp Thr Ala Gly Thr Glu Gln Phe 
    50                  55                  60


Thr Ala Met Arg Asp Leu Tyr Met Lys Asn Gly Gln Gly Phe Ala Leu 
65                  70                  75                  80


Val Tyr Ser Ile Thr Ala Gln Ser Thr Phe Asn Asp Leu Gln Asp Leu 
                85                  90                  95


Arg Glu Gln Ile Leu Arg Val Lys Asp Thr Asp Asp Val Pro Met Ile 
            100                 105                 110


Leu Val Gly Asn Lys Cys Asp Leu Glu Asp Glu Arg Val Val Gly Lys 
        115                 120                 125


Glu Gln Gly Gln Asn Leu Ala Arg Gln Trp Asn Asn Cys Ala Phe Leu 
    130                 135                 140


Glu Ser Ser Ala Lys Ser Lys Ile Asn Val Asn Glu Ile Phe Tyr Asp 
145                 150                 155                 160


Leu Val Arg Gln Ile Asn Arg Lys Thr Pro Val Pro Gly Lys Ala Arg 
                165                 170                 175


Lys Lys Ser Ser Cys Gln Leu Leu 
            180


<210>  8062
<211>  2276
<212>  DNA
<213>  Homo sapiens

<400>  8062
gacatcgcca aacctcgccc agattcaggc gtgtaaacca gccggagcgg cgcggcagcg     60

gcaggaccgc cgtggcgcct agagtagcga cccgggggga gcgcggggcg acgctggctg    120

cagggacccg gtgacagcgt gagaggtact aggttttgac aagcttgcat catgcgtgag    180

tataagctag tcgttcttgg ctcaggaggc gttggaaagt ctgctttgac tgtacaattt    240

gttcaaggaa tttttgtaga aaaatacgat cctacgatag aagattctta tagaaagcaa    300

gttgaagtag atgcacaaca gtgtatgctt gaaatcttgg atactgcagg aacggagcaa    360

tttacagcaa tgagggattt atacatgaaa aatggacaag gatttgcatt agtttattcc    420

atcacagcac agtccacatt taacgattta caagacctga gagaacagat tcttcgagtt    480

aaagacactg atgatgttcc aatgattctt gttggtaata agtgtgactt ggaagatgaa    540

agagttgtag ggaaggaaca aggtcaaaat ctagcaagac aatggaacaa ctgtgcattc    600

ttagaatctt ctgcaaaatc aaaaataaat gttaatgaga tcttttatga cctagtgcgg    660

caaattaaca gaaaaactcc agtgcctggg aaggctcgca aaaagtcatc atgtcagctg    720

ctttaatata ctaaatgcat tgtagctctg agccaggtct gaagaactgt tgcccaattc    780

aacagtgcca gcattccaac tttgttaaac ctaccaacat cttaaatgga ctttcctgtg    840

gtggtaccct ttaagaggcg gatgaaagct actatatcag tttgcacatt ctaatcactt    900

tccagtatca caagagagat ttttacttat ataatagtcc tagagtttgc agctggtaaa    960

accagaggct acatccagta ttactgctaa gagacattct tcatccacca atgttgtaca   1020

tgtatgaaaa tggtgtactg tatactttaa catgccccat actttgtatt ggagagtaca   1080

ataatgtaaa tcctaaaagc accactattt tagcataata aaagaaagtc caaagagctc   1140

ctatatagac tactccagat aacttcgctt ctttgatact tgtagcttat tgtaattttt   1200

tttaagaaat tcaaggtcat tattattgta caaaataagc gctttgatta acacagctat   1260

atagtttttt taatttttaa aaaacctgtg gagacggtga tcttgtcttt aaaacatgat   1320

agtcctttca gtataatgtc ttagattaaa gacgttgcct ttaatatctg ttgggaagga   1380

aatgtccaga cttttcaaat ctcttattat atgtttcctt tttttgttta catagggaac   1440

aatgtttata gtcgtgtgta cagtgggggt ctacaacaag aagtgtatat tttcaaacaa   1500

ttttttaatg atttaacaat ttttgtaaat cattttcagg cttctgcagc tgtagattct   1560

cactgtgaat cccttgcttg ctcatgcata agtgtatttg caataccaaa tatacaggtt   1620

tagtattttt gcctgttagt gattgtttca catgtgtaac gttttggttg agatgttaaa   1680

tggtggacga gtactgtgga tgtgaatgtg ggaagtaatt ttaatcatat gtaattggtc   1740

acaaggccta atttgcagta actattgctg ttttatttaa caatgccttg ttgctttgta   1800

tgcattaatg tttggatgta aagattgtgt gtctatccaa cagggagcca cagtatttaa   1860

attgaccaac ctaatgttac aactactttg aggtggccaa atgtaaacta aaagccttaa   1920

ttaaagtggt gcaattttgt ataacttagc atcagtagtt caataaattt ggattgccat   1980

gcaagggctt gcattataat tacttgccac ttgaatgtgt tttgtgtaat gttttaacag   2040

tgctagtaaa taaatacggg tttaccctgg ttttaattgt aataggtgca ttttacacag   2100

catggtttca taatttaaca tctgggcaag ccagactcat taattacagg aataaggaag   2160

tagcgagttt tctggtattg tttgaatatc cacataacca ccttttgaac ttttccttga   2220

gaaataattt tgtaaatcaa gcagtattac ttacgaataa atgcctttgg gtaatg       2276


<210>  8063
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  8063

Met Arg Glu Tyr Lys Leu Val Val Leu Gly Ser Gly Gly Val Gly Lys 
1               5                   10                  15


Ser Ala Leu Thr Val Gln Phe Val Gln Gly Ile Phe Val Glu Lys Tyr 
            20                  25                  30


Asp Pro Thr Ile Glu Asp Ser Tyr Arg Lys Gln Val Glu Val Asp Ala 
        35                  40                  45


Gln Gln Cys Met Leu Glu Ile Leu Asp Thr Ala Gly Thr Glu Gln Phe 
    50                  55                  60


Thr Ala Met Arg Asp Leu Tyr Met Lys Asn Gly Gln Gly Phe Ala Leu 
65                  70                  75                  80


Val Tyr Ser Ile Thr Ala Gln Ser Thr Phe Asn Asp Leu Gln Asp Leu 
                85                  90                  95


Arg Glu Gln Ile Leu Arg Val Lys Asp Thr Asp Asp Val Pro Met Ile 
            100                 105                 110


Leu Val Gly Asn Lys Cys Asp Leu Glu Asp Glu Arg Val Val Gly Lys 
        115                 120                 125


Glu Gln Gly Gln Asn Leu Ala Arg Gln Trp Asn Asn Cys Ala Phe Leu 
    130                 135                 140


Glu Ser Ser Ala Lys Ser Lys Ile Asn Val Asn Glu Ile Phe Tyr Asp 
145                 150                 155                 160


Leu Val Arg Gln Ile Asn Arg Lys Thr Pro Val Pro Gly Lys Ala Arg 
                165                 170                 175


Lys Lys Ser Ser Cys Gln Leu Leu 
            180


<210>  8064
<211>  1275
<212>  DNA
<213>  Homo sapiens

<400>  8064
taaaccagcc ggagcggcgc ggcagcggca ggaccgccgt ggcgcctaga gtaccccctc     60

gcttgtcgcc tgggttccct ccgtggtatg ggtggaagtt agaacggaaa ccagaaagtt    120

gtcctttgcg aagacctagc ttctcccagc cccgagctag ggcgaggagc cttcggggga    180

aaccactccc aggcgccccg cgggcttgag cctgacagcg aaaaagtttg cctgaaacgg    240

ggcttgcttg ctccatttgt tgcgggaagt ggcaggagga aggcagcgga gagagcccca    300

cttagtctgg cagcagccac cgtgtagaga aaaactgtta aaggggcctt tcccttcgtc    360

agcaagagga aatctctttc tcttagaggg agagaaaatc caggaagttt gtcctcttct    420

ctttttcgcc atctcgaggt gtctaatcct aaaactatca gcgccatgaa ttttatttaa    480

aactacgccc agtgaaccgg gctctccgga tttttcttct gaaaaacact gatgtctttt    540

ggagaaaaga tcatttttgc aagttaaagc agatggtttc cttccccttc gctttccccc    600

ctctcccact ctctttaata gtttagaaaa acattttggc cctgtaactt ctgattggta    660

tgaatagaag cagttctgtg ttgcagtaag gggaaatcac atttttacgg ggtagaaagt    720

tgacactaaa tgaagattgt gattttagta ttttaaaatt aattccgtct aattggattt    780

tggttttgca ggcagcatct catatatgtc gagtacttaa caatttaaag ctctgacttg    840

taaatttatt tttcagctct cttttttcgt aattagaata ctgtttggac ttgctcaaca    900

agaccttatc ttaacaaaaa gtaacttata gaaaagggag acattcattt aacttcaagc    960

ccatattatt cttaaaagct gactcttgaa atagtattta ttgagtcata gtggagtcat   1020

gggacttttt aagggccgga agggactatt tagatcatcc agtcccaccc tgtcatttta   1080

tggaggagga aactgaggcc tagataagat aaccagttag tgggtccact gacctttagg   1140

acagtagtct atccgtaaga gacaacatgg agaaagaaat acaacgtttt tatagtgaat   1200

tatcatctta caaagaatat tcttcccata tcgcactttt aaaaagtggg taccttagtc   1260

aaataggaga aaaaa                                                    1275


<210>  8065
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  8065

Met Glu Lys Glu Ile Gln Arg Phe Tyr Ser Glu Leu Ser Ser Tyr Lys 
1               5                   10                  15


Glu Tyr Ser Ser His Ile Ala Leu Leu Lys Ser Gly Tyr Leu Ser Gln 
            20                  25                  30


Ile Gly Glu 
        35


<210>  8066
<211>  1938
<212>  DNA
<213>  Homo sapiens

<400>  8066
tggtctcaaa ctcctggcct caaaagtgat cctcctgcct tggcctccca aagtgttggg     60

atttcaggaa tgagtcacca ctgtctggcc cattttcatt ttctataaag caaggctatc    120

taccaaaact taggtctgtt ttttcagtat actggggagt ctctctaaag ataaattaac    180

ataccctgta catctatcta tatgataaaa gacgctttta gttaggtatt atgtttctgt    240

tagatgtagt ttggctggta tgggtcacat tccagcatga cgtgaagtaa ggagctacac    300

atggggtatt tcgaaaagtg ggtaaaacaa aagtcacgct gggaataacg agaggtgaag    360

tttcaaggtc aggtcaaatt taaatgtgaa ggcccagaag cccgggagac ctaatcaatt    420

ttaaagtagt ggttggctac caaaccattt atactcctaa cactattatt agtaaaatct    480

ctcattctag tagggattgg gtatatttgt gtgttttaaa aaacaccctg ctgcagccta    540

ttaagccaac tgagttcctt tcctcatggg ggggcccagt gtgcaatggc tgcaaacagc    600

agcttccttg gtagtgtatg cagcctgtgt gttgtattgt atgggttgct ctaagggacc    660

ctggagacag tcctttcaga tggatgttca tgtttctgac cttgcactac cccagtgtag    720

gttccaaaca ggcatgcgag gtgcctttgg gaagccccag ggcactgtgg ccagggttca    780

cactggccaa gttatcatct ccattcacac caagctgcag aacaaggagc atgtgattga    840

ggccctgcgc agggccaagt tcaagttttc tggccgccag aagatccaca tctcaaagaa    900

gtggggcttc accaagttca atgccaatga gtttgaagac atggtgactg agaagcggct    960

catcccagat ggctgtcggg tcaagtacat ttccaatcgt ggccctgtgg acaagtggcg   1020

ggccctgcac tcatgagggc ttccactgtg ctgccccctc ttaatactca ccaataaatt   1080

ctacttcctg tccacccaaa acaaacaaac aaacaaacaa caaaaaaaaa acaccctgga   1140

aaattctgat actaccttcc ctcttcctta agacctttac ccgagaccag aaatattagg   1200

ggctgtctac taggaccatt ttattcatct ttttgcctat aaaataaatt tccccaattt   1260

aatacagaaa agggtgtctg ctattcctca gatctccaga aatcagatta ttaatacttt   1320

aaataagcta ctcaaatgcc ttaacttcca caagtcacag attaaaaatg agacactacc   1380

tccaaaggga tgactgagac tggggggaaa gaggttatcc aagatggttc tctatgtcca   1440

aaatttaaag ataccatcaa aaacgcccta taatatttgc tgaacaggtt gcaaagtaac   1500

tacaaccacc acagaaatat ccctattagt tagggaaaat aactactttc acatatttca   1560

agcaaatact atactacatg cagtttataa gctgttgggt tagaggtata agaaattgga   1620

agtgaggaac tttagtgtta gtagataaat caaggtaaga actccagaac aaagcatacc   1680

cattttcatg aatggaagaa tgccataaat atcttctcaa tataaatgct taagtggggt   1740

ggtgcttttg caaaccacca ccctccacaa ggatgggtga agctttttta aaacatgatt   1800

ttacagtctg tttcaacaca aggccgaata tagaaataaa cagaattagt gtcttccatg   1860

agaggagaaa caaatggctc agaaaaatat tttatttcat tttgctgtta acctcataac   1920

caggatcagg tgacaagc                                                 1938


<210>  8067
<211>  156
<212>  PRT
<213>  Homo sapiens

<400>  8067

Met Gly Gly Pro Ser Val Gln Trp Leu Gln Thr Ala Ala Ser Leu Val 
1               5                   10                  15


Val Tyr Ala Ala Cys Val Leu Tyr Cys Met Gly Cys Ser Lys Gly Pro 
            20                  25                  30


Trp Arg Gln Ser Phe Gln Met Asp Val His Val Ser Asp Leu Ala Leu 
        35                  40                  45


Pro Gln Cys Arg Phe Gln Thr Gly Met Arg Gly Ala Phe Gly Lys Pro 
    50                  55                  60


Gln Gly Thr Val Ala Arg Val His Thr Gly Gln Val Ile Ile Ser Ile 
65                  70                  75                  80


His Thr Lys Leu Gln Asn Lys Glu His Val Ile Glu Ala Leu Arg Arg 
                85                  90                  95


Ala Lys Phe Lys Phe Ser Gly Arg Gln Lys Ile His Ile Ser Lys Lys 
            100                 105                 110


Trp Gly Phe Thr Lys Phe Asn Ala Asn Glu Phe Glu Asp Met Val Thr 
        115                 120                 125


Glu Lys Arg Leu Ile Pro Asp Gly Cys Arg Val Lys Tyr Ile Ser Asn 
    130                 135                 140


Arg Gly Pro Val Asp Lys Trp Arg Ala Leu His Ser 
145                 150                 155


<210>  8068
<211>  3135
<212>  DNA
<213>  Homo sapiens

<400>  8068
agagcttagc aaagcctcac aagcaaatag attgaccttc tgtctcactc ataagataaa     60

ccatcttggc cacttagaaa ggccacctag ctgagaagtg tcatgcttgg aacaaactga    120

gaagtacata caatgtgaaa tgaactgctt tttcatttgt atccaaagtg atggggaggt    180

cagttgatcc tgcatgtatg tgtgtataca taacaattag tcaatttcta atttaaaaat    240

caaatttaag ctcttaagac tgaaacaatt gctgggatta caggcgtgac caccactccc    300

agccaacccc gtccctaatt taaaacacac acacacacac acacacacac acacacacac    360

acacacacac acgtgcgcgc gtgcgcgtga gccaccgctc ccagccaacc gtccctaatt    420

taaaacacac acacacacac acacccctga catgttcatc atgtgccagt cacacacaca    480

cacacacccc tgacatgttc atcatgtgcc actttttttt ttttccttca acttttaagt    540

tccaggatac atgtgcagga tgtgcaggtt tgttacatag gtaaaggtgt accatggggt    600

ttgctgcaca gatcttgcat cggtacctgg cacatagtta acactcaact attagctgct    660

gctgtttgcc aatgataatg gtttcctctt cagctgtcat taaactgttt attgttaaac    720

tgttaattta ttcttaagaa cctttgacat tcctgactct tatttcttcc tatgttaatt    780

gactcagtgc tgccatagca ctttgattct gcatcttttc agagttttta ttcctgcctt    840

ccatctaggg ctttctgttt agtggtatat cctctcattc taatatccta taattcctga    900

ccacatgccc attcttagca gcacacatgt gcttgagctc acacacttcc atctgtcctt    960

tttaatttgc aacagtctgc caggatttag aaaacttgat tgcaaacctc attcagactc   1020

agaatgagga cctaaagttc taggcatttg tgaaaattat ttcaacagcc acatatgtat   1080

taacaactct tctggagctt gtaacaagtc tgatcaccag aaaaatataa tagggaacat   1140

ttttttagcc gaggcatgta tgcagaaaac tattcaaagt acatatttaa caattctaag   1200

tttacttttt aaaatcttta attacatgtg attttagtgt aataccacct ttttctgaca   1260

tcagtcttaa tagaatgttt aaatatggaa ttagaaatta tataacgtga ttgtaaatct   1320

gtaaaacacc atcatgaaat aaattctatt tgtctgctct gaacgagctt tttagccact   1380

ttcattgaaa gagtgaggaa gaacttgatt atctgatact agaaaccttg gttagatgtg   1440

cattctatac ttatgatcta attctaggag tacattacga ttgtgtaaac acaggatcac   1500

ccagtttgtt aatattgcta tctgactttt caatcctaat tctaataagg ttgacttgac   1560

taacaatttt aatgtgattt ttttcctttt taatccttgg aaggtaatgc acaaaaattt   1620

gcacaaaggt actttccctt tctgttccta agattttcat ttaactgact ttcaagaggg   1680

cagcagaata gacttcatct ttttggaatg aaaaggtctg ccgtgaattg tggtatgttg   1740

ccactaatgt aatgcctaga acaagagcct agattatatt catttctaac acttttaaga   1800

ctgttttctt aactgtttgc ttttgggtct ttactttttc tagcccatgt ttttaattaa   1860

tttttttcct tttgacaggt ctgaagaact gttgcccaat tcaacagtgc cagcattcca   1920

actttgttaa acctaccaac atcttaaatg gactttcctg tggtggtacc ctttaagagg   1980

cggatgaaag ctactatatc agtttgcaca ttctaatcac tttccagtat cacaagagag   2040

atttttactt atataatagt cctagagttt gcagctggta aaaccagagg ctacatccag   2100

tattactgct aagagacatt cttcatccac caatgttgta catgtatgaa aatggtgtac   2160

tgtatacttt aacatgcccc atactttgta ttggagagta caataatgta aatcctaaaa   2220

gcaccactat tttagcataa taaaagaaag tccaaagagc tcctatatag actactccag   2280

ataacttcgc ttctttgata cttgtagctt attgtaattt tttttaagaa attcaaggtc   2340

attattattg tacaaaataa gcgctttgat taacacagct atatagtttt tttaattttt   2400

aaaaaacctg tggagacggt gatcttgtct ttaaaacatg atagtccttt cagtataatg   2460

tcttagatta aagacgttgc ctttaatatc tgttgggaag gaaatgtcca gacttttcaa   2520

atctcttatt atatgtttcc tttttttgtt tacataggga acaatgttta tagtcgtgtg   2580

tacagtgggg gtctacaaca agaagtgtat attttcaaac aattttttaa tgatttaaca   2640

atttttgtaa atcattttca ggcttctgca gctgtagatt ctcactgtga atcccttgct   2700

tgctcatgca taagtgtatt tgcaatacca aatatacagg tttagtattt ttgcctgtta   2760

gtgattgttt cacatgtgta acgttttggt tgagatgtta aatggtggac gagtactgtg   2820

gatgtgaatg tgggaagtaa ttttaatcat atgtaattgg tcacaaggcc taatttgcag   2880

taactattgc tgttttattt aacaatgcct tgttgctttg tatgcattaa tgtttggatg   2940

taaagattgt gtgtctatcc aacagggagc cacagtattt aaattgacca acctaatgtt   3000

acaactactt tgaggtggcc aaatgtaaac taaaagcctt aattaaagtg gtgcaatttt   3060

gtataactta gcatcagtag ttcaataaat ttggattgcc atgcaagggc ttgcattata   3120

attacttgcc acttg                                                    3135


<210>  8069
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8069

Met Phe Pro Phe Phe Val Tyr Ile Gly Asn Asn Val Tyr Ser Arg Val 
1               5                   10                  15


Tyr Ser Gly Gly Leu Gln Gln Glu Val Tyr Ile Phe Lys Gln Phe Phe 
            20                  25                  30


Asn Asp Leu Thr Ile Phe Val Asn His Phe Gln Ala Ser Ala Ala Val 
        35                  40                  45


Asp Ser His Cys Glu Ser Leu Ala Cys Ser Cys Ile Ser Val Phe Ala 
    50                  55                  60


Ile Pro Asn Ile Gln Val 
65                  70


<210>  8070
<211>  3202
<212>  DNA
<213>  Homo sapiens

<400>  8070
agagcttagc aaagcctcac aagcaaatag attgaccttc tgtctcactc ataagataaa     60

ccatcttggc cacttagaaa ggccacctag ctgagaagtg tcatgcttgg aacaaactga    120

gaagtacata caatgtgaaa tgaactgctt tttcatttgt atccaaagtg atggggaggt    180

cagttgatcc tgcatgtatg tgtgtataca taacaattag tcaatttcta atttaaaaat    240

caaatttaag ctcttaagac tgaaacaatt gctgggatta caggcgtgac caccactccc    300

agccaacccc gtccctaatt taaaacacac acacacacac acacacacac acacacacac    360

acacacacac acgtgcgcgc gtgcgcgtga gccaccgctc ccagccaacc gtccctaatt    420

taaaacacac acacacacac acacccctga catgttcatc atgtgccagt cacacacaca    480

cacacacccc tgacatgttc atcatgtgcc actttttttt ttttccttca acttttaagt    540

tccaggatac atgtgcagga tgtgcaggtt tgttacatag gtaaaggtgt accatggggt    600

ttgctgcaca gatcttgcat cggtacctgg cacatagtta acactcaact attagctgct    660

gctgtttgcc aatgataatg gtttcctctt cagctgtcat taaactgttt attgttaaac    720

tgttaattta ttcttaagaa cctttgacat tcctgactct tatttcttcc tatgttaatt    780

gactcagtgc tgccatagca ctttgattct gcatcttttc agagttttta ttcctgcctt    840

ccatctaggg ctttctgttt agtggtatat cctctcattc taatatccta taattcctga    900

ccacatgccc attcttagca gcacacatgt gcttgagctc acacacttcc atctgtcctt    960

tttaatttgc aacagtctgc caggatttag aaaacttgat tgcaaacctc attcagactc   1020

agaatgagga cctaaagttc taggcatttg tgaaaattat ttcaacagcc acatatgtat   1080

taacaactct tctggagctt gtaacaagtc tgatcaccag aaaaatataa tagggaacat   1140

ttttttagcc gaggcatgta tgcagaaaac tattcaaagt acatatttaa caattctaag   1200

tttacttttt aaaatcttta attacatgtg attttagtgt aataccacct ttttctgaca   1260

tcagtcttaa tagaatgttt aaatatggaa ttagaaatta tataacgtga ttgtaaatct   1320

gtaaaacacc atcatgaaat aaattctatt tgtctgctct gaacgagctt tttagccact   1380

ttcattgaaa gagtgaggaa gaacttgatt atctgatact agaaaccttg gttagatgtg   1440

cattctatac ttatgatcta attctaggag tacattacga ttgtgtaaac acaggatcac   1500

ccagtttgtt aatattgcta tctgactttt caatcctaat tctaataagg ttgacttgac   1560

taacaatttt aatgtgattt ttttcctttt taatccttgg aaggtaatgc acaaaaattt   1620

gcacaaaggt actttccctt tctgttccta agattttcat ttaactgact ttcaagaggg   1680

cagcagaata gacttcatct ttttggaatg aaaaggtctg ccgtgaattg tggtatgttg   1740

ccactaatgt aatgcctaga acaagagcct agattatatt catttctaac acttttaaga   1800

ctgttttctt aactgtttgc ttttgggtct ttactttttc tagcccatgt ttttaattaa   1860

tttttttcct tttgacaggt ctgaagaact gttgcccaat tcaacagtgc cagcattcca   1920

actttgttaa acctaccaac atcttaaatg gactttcctg tggtggtacc ctttaagagg   1980

cggatgaaag ctactatatc agtttgcaca ttctaatcac tttccagtat cacaagagag   2040

atttttactt atataatagt cctagagttt gcagctggta aaaccagagg ctacatccag   2100

tattactgct aagagacatt cttcatccac caatgttgta catgtatgaa aatggtgtac   2160

tgtatacttt aacatgcccc atactttgta ttggagagta caataatgta aatcctaaaa   2220

gcaccactat tttagcataa taaaagaaag tccaaagagc tcctatatag actactccag   2280

ataacttcgc ttctttgata cttgtagctt attgtaattt tttttaagaa attcaaggtc   2340

attattattg tacaaaataa gcgctttgat taacacagct atatagtttt tttaattttt   2400

aaaaaacctg tggagacggt gatcttgtct ttaaaacatg atagtccttt cagtataatg   2460

tcttagatta aagacgttgc ctttaatatc tgttgggaag gaaatgtcca gacttttcaa   2520

atctcttatt atatgtttcc tttttttgtt tacataggga acaatgttta tagtcgtgtg   2580

tacagtgggg gtctacaaca agaagtgtat attttcaaac aattttttaa tgatttaaca   2640

atttttgtaa atcattttca ggcttctgca gctgtagatt ctcactgtga atcccttgct   2700

tgctcatgca taagtgtatt tgcaatacca aatatacagg tttagtattt ttgcctgtta   2760

gtgattgttt cacatgtgta acgttttggt tgagatgtta aatggtggac gagtactgtg   2820

gatgtgaatg tgggaagtaa ttttaatcat atgtaattgg tcacaaggcc taatttgcag   2880

taactattgc tgttttattt aacaatgcct tgttgctttg tatgcattaa tgtttggatg   2940

taaagattgt gtgtctatcc aacagggagc cacagtattt aaattgacca acctaatgtt   3000

acaactactt tgaggtggcc aaatgtaaac taaaagcctt aattaaagtg gtgcaatttt   3060

gtataactta gcatcagtag ttcaataaat ttggattgcc atgcaagggc ttgcattata   3120

attacttgcc acttgaatgt gttttgtgta atgttttaac agtgctagta aataaatacg   3180

ggtttaccct ggttttaatt gt                                            3202


<210>  8071
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8071

Met Phe Pro Phe Phe Val Tyr Ile Gly Asn Asn Val Tyr Ser Arg Val 
1               5                   10                  15


Tyr Ser Gly Gly Leu Gln Gln Glu Val Tyr Ile Phe Lys Gln Phe Phe 
            20                  25                  30


Asn Asp Leu Thr Ile Phe Val Asn His Phe Gln Ala Ser Ala Ala Val 
        35                  40                  45


Asp Ser His Cys Glu Ser Leu Ala Cys Ser Cys Ile Ser Val Phe Ala 
    50                  55                  60


Ile Pro Asn Ile Gln Val 
65                  70


<210>  8072
<211>  3398
<212>  DNA
<213>  Homo sapiens

<400>  8072
agagcttagc aaagcctcac aagcaaatag attgaccttc tgtctcactc ataagataaa     60

ccatcttggc cacttagaaa ggccacctag ctgagaagtg tcatgcttgg aacaaactga    120

gaagtacata caatgtgaaa tgaactgctt tttcatttgt atccaaagtg atggggaggt    180

cagttgatcc tgcatgtatg tgtgtataca taacaattag tcaatttcta atttaaaaat    240

caaatttaag ctcttaagac tgaaacaatt gctgggatta caggcgtgac caccactccc    300

agccaacccc gtccctaatt taaaacacac acacacacac acacacacac acacacacac    360

acacacacac acgtgcgcgc gtgcgcgtga gccaccgctc ccagccaacc gtccctaatt    420

taaaacacac acacacacac acacccctga catgttcatc atgtgccagt cacacacaca    480

cacacacccc tgacatgttc atcatgtgcc actttttttt ttttccttca acttttaagt    540

tccaggatac atgtgcagga tgtgcaggtt tgttacatag gtaaaggtgt accatggggt    600

ttgctgcaca gatcttgcat cggtacctgg cacatagtta acactcaact attagctgct    660

gctgtttgcc aatgataatg gtttcctctt cagctgtcat taaactgttt attgttaaac    720

tgttaattta ttcttaagaa cctttgacat tcctgactct tatttcttcc tatgttaatt    780

gactcagtgc tgccatagca ctttgattct gcatcttttc agagttttta ttcctgcctt    840

ccatctaggg ctttctgttt agtggtatat cctctcattc taatatccta taattcctga    900

ccacatgccc attcttagca gcacacatgt gcttgagctc acacacttcc atctgtcctt    960

tttaatttgc aacagtctgc caggatttag aaaacttgat tgcaaacctc attcagactc   1020

agaatgagga cctaaagttc taggcatttg tgaaaattat ttcaacagcc acatatgtat   1080

taacaactct tctggagctt gtaacaagtc tgatcaccag aaaaatataa tagggaacat   1140

ttttttagcc gaggcatgta tgcagaaaac tattcaaagt acatatttaa caattctaag   1200

tttacttttt aaaatcttta attacatgtg attttagtgt aataccacct ttttctgaca   1260

tcagtcttaa tagaatgttt aaatatggaa ttagaaatta tataacgtga ttgtaaatct   1320

gtaaaacacc atcatgaaat aaattctatt tgtctgctct gaacgagctt tttagccact   1380

ttcattgaaa gagtgaggaa gaacttgatt atctgatact agaaaccttg gttagatgtg   1440

cattctatac ttatgatcta attctaggag tacattacga ttgtgtaaac acaggatcac   1500

ccagtttgtt aatattgcta tctgactttt caatcctaat tctaataagg ttgacttgac   1560

taacaatttt aatgtgattt ttttcctttt taatccttgg aaggtaatgc acaaaaattt   1620

gcacaaaggt actttccctt tctgttccta agattttcat ttaactgact ttcaagaggg   1680

cagcagaata gacttcatct ttttggaatg aaaaggtctg ccgtgaattg tggtatgttg   1740

ccactaatgt aatgcctaga acaagagcct agattatatt catttctaac acttttaaga   1800

ctgttttctt aactgtttgc ttttgggtct ttactttttc tagcccatgt ttttaattaa   1860

tttttttcct tttgacaggt ctgaagaact gttgcccaat tcaacagtgc cagcattcca   1920

actttgttaa acctaccaac atcttaaatg gactttcctg tggtggtacc ctttaagagg   1980

cggatgaaag ctactatatc agtttgcaca ttctaatcac tttccagtat cacaagagag   2040

atttttactt atataatagt cctagagttt gcagctggta aaaccagagg ctacatccag   2100

tattactgct aagagacatt cttcatccac caatgttgta catgtatgaa aatggtgtac   2160

tgtatacttt aacatgcccc atactttgta ttggagagta caataatgta aatcctaaaa   2220

gcaccactat tttagcataa taaaagaaag tccaaagagc tcctatatag actactccag   2280

ataacttcgc ttctttgata cttgtagctt attgtaattt tttttaagaa attcaaggtc   2340

attattattg tacaaaataa gcgctttgat taacacagct atatagtttt tttaattttt   2400

aaaaaacctg tggagacggt gatcttgtct ttaaaacatg atagtccttt cagtataatg   2460

tcttagatta aagacgttgc ctttaatatc tgttgggaag gaaatgtcca gacttttcaa   2520

atctcttatt atatgtttcc tttttttgtt tacataggga acaatgttta tagtcgtgtg   2580

tacagtgggg gtctacaaca agaagtgtat attttcaaac aattttttaa tgatttaaca   2640

atttttgtaa atcattttca ggcttctgca gctgtagatt ctcactgtga atcccttgct   2700

tgctcatgca taagtgtatt tgcaatacca aatatacagg tttagtattt ttgcctgtta   2760

gtgattgttt cacatgtgta acgttttggt tgagatgtta aatggtggac gagtactgtg   2820

gatgtgaatg tgggaagtaa ttttaatcat atgtaattgg tcacaaggcc taatttgcag   2880

taactattgc tgttttattt aacaatgcct tgttgctttg tatgcattaa tgtttggatg   2940

taaagattgt gtgtctatcc aacagggagc cacagtattt aaattgacca acctaatgtt   3000

acaactactt tgaggtggcc aaatgtaaac taaaagcctt aattaaagtg gtgcaatttt   3060

gtataactta gcatcagtag ttcaataaat ttggattgcc atgcaagggc ttgcattata   3120

attacttgcc acttgaatgt gttttgtgta atgttttaac agtgctagta aataaatacg   3180

ggtttaccct ggttttaatt gtaataggtg cattttacac agcatggttt cataatttaa   3240

catctgggca agccagactc attaattaca ggaataagga agtagcgagt tttctggtat   3300

tgtttgaata tccacataac caccttttga acttttcctt gagaaataat tttgtaaatc   3360

aagcagtatt acttacgaat aaatgccttt gggtaatg                           3398


<210>  8073
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8073

Met Phe Pro Phe Phe Val Tyr Ile Gly Asn Asn Val Tyr Ser Arg Val 
1               5                   10                  15


Tyr Ser Gly Gly Leu Gln Gln Glu Val Tyr Ile Phe Lys Gln Phe Phe 
            20                  25                  30


Asn Asp Leu Thr Ile Phe Val Asn His Phe Gln Ala Ser Ala Ala Val 
        35                  40                  45


Asp Ser His Cys Glu Ser Leu Ala Cys Ser Cys Ile Ser Val Phe Ala 
    50                  55                  60


Ile Pro Asn Ile Gln Val 
65                  70


<210>  8074
<211>  1152
<212>  DNA
<213>  Homo sapiens

<400>  8074
ttctaacact tttaagactg ttttcttaac tgtttgcttt tgggtcttta ctttttctag     60

cccatgtttt taattaattt ttttcctttt gacaggtctg aagaactgtt gcccaattca    120

acagtgccag cattccaact ttgttaaacc taccaacatc ttaaatggac tttcctgtgg    180

tggtaccctt taagaggcgg atgaaagcta ctatatcagt ttgcacattc taatcacttt    240

ccagtatcac aagagagatt tttacttata taatagtcct agagtttgca gctggtaaaa    300

ccagaggcta catccagtat tactgctaag agacattctt catccaccaa tgttgtacat    360

gtatgaaaat ggtgtactgt atactttaac atgccccata ctttgtattg gagagtacaa    420

taatgtaaat cctaaaagca ccactatttt agcataataa aagaaagtcc aaagagctcc    480

tatatagact actccagata acttcgcttc tttgatactt gtagcttatt gtaatttttt    540

ttaagaaatt caaggtcatt attattgtac aaaataagcg ctttgattaa cacagctata    600

tagttttttt aatttttaaa aaacctgtgg agacggtgat cttgtcttta aaacatgata    660

gtcctttcag tataatgtct tagattaaag acgttgcctt taatatctgt tgggaaggaa    720

atgtccagac ttttcaaatc tcttattata tgtttccttt ttttgtttac atagggaaca    780

atgtttatag tcgtgtgtac agtgggggtc tacaacaaga agtgtatatt ttcaaacaat    840

tttttaatga tttaacaatt tttgtaaatc attttcaggc ttctgcagct gtagattctc    900

actgtgaatc ccttgcttgc tcatgcataa gtgtatttgc aataccaaat atacaggttt    960

agtatttttg cctgttagtg attgtttcac atgtttaaca tctgggcaag ccagactcat   1020

taattacagg aataaggaag tagcgagttt tctggtattg tttgaatatc cacataacca   1080

ccttttgaac ttttccttga gaaataattt tgtaaatcaa gcagtattac ttacgaataa   1140

atgcctttgg gt                                                       1152


<210>  8075
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  8075

Met His Lys Cys Ile Cys Asn Thr Lys Tyr Thr Gly Leu Val Phe Leu 
1               5                   10                  15


Pro Val Ser Asp Cys Phe Thr Cys Leu Thr Ser Gly Gln Ala Arg Leu 
            20                  25                  30


Ile Asn Tyr Arg Asn Lys Glu Val Ala Ser Phe Leu Val Leu Phe Glu 
        35                  40                  45


Tyr Pro His Asn His Leu Leu Asn Phe Ser Leu Arg Asn Asn Phe Val 
    50                  55                  60


Asn Gln Ala Val Leu Leu Thr Asn Lys Cys Leu 
65                  70                  75


<210>  8076
<211>  2091
<212>  DNA
<213>  Homo sapiens

<400>  8076
aaatttcccg gcatggggaa ggagccttag gggaagcacc cgggacctcc ttggcttctt     60

ctgggagtct agtttcacct atttcgtttc gccaacaggc gagacgggca agacttcggg    120

ctcagctgcc accatcagta ctgacctgtc catggctaaa gccttttcca cacacaacca    180

aagttggctg cagtttagct accgcgtttt agccttcccg ctctccggaa gcaagccctt    240

cgacccggaa gcagtctgtc cctaaaacag acccacagaa aaggggtagg ggagaagaaa    300

caacgttccc atctagcgca tgcgcgactt cagcctacag gtgcacgccc ggtgggcgca    360

ggcgcaaaag tttgccaatg tgttcctggt tgcgtttagc ccagacgccc tgcggccgct    420

ttgcctgacc aaagtctgtg ggcgtggaac aggccctggg ttctcctact gggaagaatg    480

aagttcaggt actccatgtg atatatggtt ccacaatcct cagcgtgtta actgaagcct    540

tgttgagttt aacaaagctg ccattgaaga tctggggaaa gtgaagaagt tgcaacagag    600

ttttgggctc acaccattga tacatttgat ccttaaggca agcccacccc gcctcactcc    660

caccctcttc tacttaattc aggatgtgaa tagcacatgc cttccatctt cagacaaaca    720

ctgaggcctg gacaatgacc tgcattaggt agatagaatc tactgaaagc taaaagcctt    780

ttcctgtgtc ttagcagcac ggaagccacg cctccttccc cccaatgttt gtgcaaaccc    840

tagagaagag gagacagccc ctatgatgtg tgaggttgaa tttcctgccc tcaacccatc    900

aaatcaggca gaatgagggc tcagtcagaa ctacaactac aaaagagaaa aattttaatg    960

tgacttttct tgtctgctca gatttttggg ttaaggttca tgccagctac attctttgca   1020

taataaaata taaatagagt ataaattgtt ctagttagag aaaacagcaa aacagtgctc   1080

tcccaagggc cctaataaat cactttacag aaacgtggat gtgtgttgga tttacaggat   1140

ttctatgcca agcagagaag tacgtgaaaa caggaaagca aaatgcataa gttgcaataa   1200

tagttttgtg gtttagctga ataatgtcct atatcaacag aggataatga ttttagtttt   1260

tcagttgccc caagatcatt tccattactg atgaggcttg aaatgtctgt gaagaagagt   1320

cattgcaatt gatttatttg tctggcaaac tttttgtcag caaattcacc actacctcaa   1380

aaatctcact agctactcta tgcttaagac attggaagca taagccacaa tgaaaactaa   1440

ctcttagcat tagaattcta agaagcagta atgtatttat gattttatgt taaaaatctc   1500

ccagatgtca gcatttaaat cacaattcag taatataagt aatttgaaat tagaaagttt   1560

tatacttcac cattctattt tcctcttcaa attgaacaca gtttgaaaga attaagaaaa   1620

gaagctataa aaaataaatt gttcaaggat tcttcctgtt tctaaacacc acaagattat   1680

gatgatagag acatcatttg aagtggtaga gagtactgtg aaatatctat atgtgaatgt   1740

aatgaaaatg aaaaaataat ctgatgaatt tttaaaatta atcttgttag agtcattttt   1800

gagaaattgt atgcaagtgt attgattgaa aatgaccttc tcattcaaga aaaatttatt   1860

gagcacttac caagtgtcaa caggtgaatg tgaataaaat agatatggtc cctgccttct   1920

tggagttgaa taaaatagca aacacttatt gaatatttat tatatgttgt gcattataat   1980

attaaccaat gtttattgag ttgttattat atgccaacta tgccaatcct gtcctaagca   2040

atttatgtat gttaactaat ttaatcctca caataaatct atgaggtagg t            2091


<210>  8077
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8077

Met Arg Asp Phe Ser Leu Gln Val His Ala Arg Trp Ala Gln Ala Gln 
1               5                   10                  15


Lys Phe Ala Asn Val Phe Leu Val Ala Phe Ser Pro Asp Ala Leu Arg 
            20                  25                  30


Pro Leu Cys Leu Thr Lys Val Cys Gly Arg Gly Thr Gly Pro Gly Phe 
        35                  40                  45


Ser Tyr Trp Glu Glu 
    50


<210>  8078
<211>  2431
<212>  DNA
<213>  Homo sapiens

<400>  8078
ttcaacgcct ttagaacaat ggcagtcaca tagtaggtac tcaatgtttg gagtacgaat     60

aatgtactct tattattcaa agaccagcta gaaagttacc ttctttgagg ggtcttcctg    120

atagttacag tgacaaggag acttaatcgc ccccaaacac ttaccacttt acactgcttg    180

gttgtctcca ttacacaact aattccccga ggggaaggat cttgaataac tgatctttgt    240

tgtaggcggc tagcacagta cccagatcat agagggaact cagaatctga tgctggcact    300

tgtaatcaga aagtctgggc tgagatccca gtatcttcac tgactggctt tgtgatctca    360

ggctggtcac ttagcatttc gaacgccgcg ctacctaccc cgcccacccc aggagcgaac    420

agtgttgctg ccccaaagcg ccgaatagat cgcagaacgt agtgggaaag taagggacta    480

ttatgatctg taccccaccc cgacgcacgc caagcggctt tttccccatt tgtggccaaa    540

tttcccggca tggggaagga gccttagggg aagcacccgg gacctccttg gcttcttctg    600

ggagtctagt ttcacctatt tcgtttcgcc aacaggcgag acgggcaaga cttcgggctc    660

agctgccacc atcagtactg acctgtccat ggctaaagcc ttttccacac acaaccaaag    720

ttggctgcag tttagctacc gcgttttagc cttcccgctc tccggaagca agcccttcga    780

cccggaagca gtctgtccct aaaacagacc cacagaaaag gggttcaggt actccatgtg    840

atatatggtt ccacaatcct cagcgtgtta actgaagcct tgttgagttt aacaaagctg    900

ccattgaaga tctggggaaa gtgaagaagt tgcaacagag ttttgggctc acaccattga    960

tacatttgat ccttaaggca agcccacccc gcctcactcc caccctcttc tacttaattc   1020

aggatgtgaa tagcacatgc cttccatctt cagacaaaca ctgaggcctg gacaatgacc   1080

tgcattaggt agatagaatc tactgaaagc taaaagcctt ttcctgtgtc ttagcagcac   1140

ggaagccacg cctccttccc cccaatgttt gtgcaaaccc tagagaagag gagacagccc   1200

ctatgatgtg tgaggttgaa tttcctgccc tcaacccatc aaatcaggca gaatgagggc   1260

tcagtcagaa ctacaactac aaaagagaaa aattttaatg tgacttttct tgtctgctca   1320

gatttttggg ttaaggttca tgccagctac attctttgca taataaaata taaatagagt   1380

ataaattgtt ctagttagag aaaacagcaa aacagtgctc tcccaagggc cctaataaat   1440

cactttacag aaacgtggat gtgtgttgga tttacaggat ttctatgcca agcagagaag   1500

tacgtgaaaa caggaaagca aaatgcataa gttgcaataa tagttttgtg gtttagctga   1560

ataatgtcct atatcaacag aggataatga ttttagtttt tcagttgccc caagatcatt   1620

tccattactg atgaggcttg aaatgtctgt gaagaagagt cattgcaatt gatttatttg   1680

tctggcaaac tttttgtcag caaattcacc actacctcaa aaatctcact agctactcta   1740

tgcttaagac attggaagca taagccacaa tgaaaactaa ctcttagcat tagaattcta   1800

agaagcagta atgtatttat gattttatgt taaaaatctc ccagatgtca gcatttaaat   1860

cacaattcag taatataagt aatttgaaat tagaaagttt tatacttcac cattctattt   1920

tcctcttcaa attgaacaca gtttgaaaga attaagaaaa gaagctataa aaaataaatt   1980

gttcaaggat tcttcctgtt tctaaacacc acaagattat gatgatagag acatcatttg   2040

aagtggtaga gagtactgtg aaatatctat atgtgaatgt aatgaaaatg aaaaaataat   2100

ctgatgaatt tttaaaatta atcttgttag agtcattttt gagaaattgt atgcaagtgt   2160

attgattgaa aatgaccttc tcattcaaga aaaatttatt gagcacttac caagtgtcaa   2220

caggtgaatg tgaataaaat agatatggtc cctgccttct tggagttgaa taaaatagca   2280

aacacttatt gaatatttat tatatgttgt gcattataat attaaccaat gtttattgag   2340

ttgttattat atgccaacta tgccaatcct gtcctaagca atttatgtat gttaactaat   2400

ttaatcctca caataaatct atgaggtagg t                                  2431


<210>  8079
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  8079

Met Ile Cys Thr Pro Pro Arg Arg Thr Pro Ser Gly Phe Phe Pro Ile 
1               5                   10                  15


Cys Gly Gln Ile Ser Arg His Gly Glu Gly Ala Leu Gly Glu Ala Pro 
            20                  25                  30


Gly Thr Ser Leu Ala Ser Ser Gly Ser Leu Val Ser Pro Ile Ser Phe 
        35                  40                  45


Arg Gln Gln Ala Arg Arg Ala Arg Leu Arg Ala Gln Leu Pro Pro Ser 
    50                  55                  60


Val Leu Thr Cys Pro Trp Leu Lys Pro Phe Pro His Thr Thr Lys Val 
65                  70                  75                  80


Gly Cys Ser Leu Ala Thr Ala Phe 
                85


<210>  8080
<211>  1110
<212>  DNA
<213>  Homo sapiens

<400>  8080
aaatttcccg gcatggggaa ggagccttag gggaagcacc cgggacctcc ttggcttctt     60

ctgggagtct agtttcacct atttcgtttc gccaacaggc gagacgggca agacttcggg    120

ctcagctgcc accatcagta ctgacctgtc catggctaaa gccttttcca cacacaacca    180

aagttggctg cagtttagct accgcgtttt agccttcccg ctctccggaa gcaagccctt    240

cgacccggaa gcagtctgtc cctaaaacag acccacagaa aaggggtagg ggagaagaaa    300

caacgttccc atctagcgca tgcgcgactt cagcctacag gtgcacgccc ggtgggcgca    360

ggcgcaaaag tttgccaatg tgttcctggt tgcgtttagc ccagacgccc tgcggccgct    420

ttgcctgacc aaagtctgtg ggcgtggaac aggccctggg ttctcctact gggaagaatg    480

aagttcaggt actccatgtg atatatggtt ccacaatcct cagcgtgtta actgaagcct    540

tgttgagttt aacaaagctg ccattgaaga tctggggaaa gtgaagaagt tgcaacagag    600

ttttgggctc acaccattga tacatttgat ccttaaggca agcccacccc gcctcactcc    660

caccctcttc tacttaattc aggatgtgaa tagcacatgc cttccatctt cagacaaaca    720

ctgaggcctg gacaatgacc tgcattaggt agatagaatc tactgaaagc taaaagcctt    780

ttcctgtgtc ttagcagcac ggaagccacg cctccttccc cccaatgttt gtgcaaaccc    840

tagagaagag gagacagccc ctatgatgtg tgaggttgaa tttcctgccc tcaacccatc    900

aaatcaggca gaatgagggc tcagtcagaa ctacaactac aaaagagaaa aattttaatg    960

tgacttttct tgtctgctca gatttttggg ttaaggttca tgccagctac attctttgca   1020

taataaaata taaatagagt ataaattgtt ctagttagag aaaacagcaa aacagtgctc   1080

tcccaagggc cctaataaat cactttacag                                    1110


<210>  8081
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8081

Met Arg Asp Phe Ser Leu Gln Val His Ala Arg Trp Ala Gln Ala Gln 
1               5                   10                  15


Lys Phe Ala Asn Val Phe Leu Val Ala Phe Ser Pro Asp Ala Leu Arg 
            20                  25                  30


Pro Leu Cys Leu Thr Lys Val Cys Gly Arg Gly Thr Gly Pro Gly Phe 
        35                  40                  45


Ser Tyr Trp Glu Glu 
    50


<210>  8082
<211>  1450
<212>  DNA
<213>  Homo sapiens

<400>  8082
ttcaacgcct ttagaacaat ggcagtcaca tagtaggtac tcaatgtttg gagtacgaat     60

aatgtactct tattattcaa agaccagcta gaaagttacc ttctttgagg ggtcttcctg    120

atagttacag tgacaaggag acttaatcgc ccccaaacac ttaccacttt acactgcttg    180

gttgtctcca ttacacaact aattccccga ggggaaggat cttgaataac tgatctttgt    240

tgtaggcggc tagcacagta cccagatcat agagggaact cagaatctga tgctggcact    300

tgtaatcaga aagtctgggc tgagatccca gtatcttcac tgactggctt tgtgatctca    360

ggctggtcac ttagcatttc gaacgccgcg ctacctaccc cgcccacccc aggagcgaac    420

agtgttgctg ccccaaagcg ccgaatagat cgcagaacgt agtgggaaag taagggacta    480

ttatgatctg taccccaccc cgacgcacgc caagcggctt tttccccatt tgtggccaaa    540

tttcccggca tggggaagga gccttagggg aagcacccgg gacctccttg gcttcttctg    600

ggagtctagt ttcacctatt tcgtttcgcc aacaggcgag acgggcaaga cttcgggctc    660

agctgccacc atcagtactg acctgtccat ggctaaagcc ttttccacac acaaccaaag    720

ttggctgcag tttagctacc gcgttttagc cttcccgctc tccggaagca agcccttcga    780

cccggaagca gtctgtccct aaaacagacc cacagaaaag gggttcaggt actccatgtg    840

atatatggtt ccacaatcct cagcgtgtta actgaagcct tgttgagttt aacaaagctg    900

ccattgaaga tctggggaaa gtgaagaagt tgcaacagag ttttgggctc acaccattga    960

tacatttgat ccttaaggca agcccacccc gcctcactcc caccctcttc tacttaattc   1020

aggatgtgaa tagcacatgc cttccatctt cagacaaaca ctgaggcctg gacaatgacc   1080

tgcattaggt agatagaatc tactgaaagc taaaagcctt ttcctgtgtc ttagcagcac   1140

ggaagccacg cctccttccc cccaatgttt gtgcaaaccc tagagaagag gagacagccc   1200

ctatgatgtg tgaggttgaa tttcctgccc tcaacccatc aaatcaggca gaatgagggc   1260

tcagtcagaa ctacaactac aaaagagaaa aattttaatg tgacttttct tgtctgctca   1320

gatttttggg ttaaggttca tgccagctac attctttgca taataaaata taaatagagt   1380

ataaattgtt ctagttagag aaaacagcaa aacagtgctc tcccaagggc cctaataaat   1440

cactttacag                                                          1450


<210>  8083
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  8083

Met Ile Cys Thr Pro Pro Arg Arg Thr Pro Ser Gly Phe Phe Pro Ile 
1               5                   10                  15


Cys Gly Gln Ile Ser Arg His Gly Glu Gly Ala Leu Gly Glu Ala Pro 
            20                  25                  30


Gly Thr Ser Leu Ala Ser Ser Gly Ser Leu Val Ser Pro Ile Ser Phe 
        35                  40                  45


Arg Gln Gln Ala Arg Arg Ala Arg Leu Arg Ala Gln Leu Pro Pro Ser 
    50                  55                  60


Val Leu Thr Cys Pro Trp Leu Lys Pro Phe Pro His Thr Thr Lys Val 
65                  70                  75                  80


Gly Cys Ser Leu Ala Thr Ala Phe 
                85


<210>  8084
<211>  931
<212>  DNA
<213>  Homo sapiens

<400>  8084
aaatttcccg gcatggggaa ggagccttag gggaagcacc cgggacctcc ttggcttctt     60

ctgggagtct agtttcacct atttcgtttc gccaacaggc gagacgggca agacttcggg    120

ctcagctgcc accatcagta ctgacctgtc catggctaaa gccttttcca cacacaacca    180

aagttggctg cagtttagct accgcgtttt agccttcccg ctctccggaa gcaagccctt    240

cgacccggaa gcagtctgtc cctaaaacag acccacagaa aaggggtagg ggagaagaaa    300

caacgttccc atctagcgca tgcgcgactt cagcctacag gtgcacgccc ggtgggcgca    360

ggcgcaaaag tttgccaatg tgttcctggt tgcgtttagc ccagacgccc tgcggccgct    420

ttgcctgacc aaagtctgtg ggcgtggaac aggccctggg ttctcctact gggaagaatg    480

aagttcaggt actccatgtg atatatggtt ccacaatcct cagcgtgtta actgaagcct    540

tgttgagttt aacaaagctg ccattgaaga tctggggaaa gtgaagaagt tgcaacagag    600

ttttgggctc acaccattga tacatttgat ccttaaggca agtgacaatt tgggtttcac    660

aggtatatag aaattgccag cttttcttgc catatatttc ttgtgacagt gctgagcttt    720

ttttttttac ttcttgcttg cttttttttg gacttgattt tttaaattat gtttccttcc    780

ttccttcttt ctttgttttt tttttttttg agacaggatc ttgtcctatt gtcccggctt    840

acgtgcagtg gcacagtcac ggctcactgc agccttgacc tcctgggctc cagcaatcct    900

cctacctcag cctccctagt acctgaggtt g                                   931


<210>  8085
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8085

Met Phe Pro Ser Phe Leu Leu Ser Leu Phe Phe Phe Phe Leu Arg Gln 
1               5                   10                  15


Asp Leu Val Leu Leu Ser Arg Leu Thr Cys Ser Gly Thr Val Thr Ala 
            20                  25                  30


His Cys Ser Leu Asp Leu Leu Gly Ser Ser Asn Pro Pro Thr Ser Ala 
        35                  40                  45


Ser Leu Val Pro Glu 
    50


<210>  8086
<211>  3123
<212>  DNA
<213>  Homo sapiens

<400>  8086
gttttaggga cagactgctt ccgggtcgaa gggcttgctt ccggagagcg ggaaggctaa     60

aacgcggtag ctaaactgca gccaactttg gttgtgtgtg gaaaaggctt tagccatgga    120

caggagtggc tttggagaga tatcatcccc tgtaatccgg gaggcagagg tgacacggac    180

tgcacggaaa cagagtgctc agaaaagagt tttacttcag gcatctcaag atgaaaattt    240

tggtaatact acaccaagaa accaggttat ccctcgaact cctagctcat ttcgacagcc    300

ttttacccca acaagccgaa gcttactaag gcagccagat atttcctgca ttcttggaac    360

aggagggaag tcgccccgac ttacgcagtc ttcagggttc tttggaaatc tctccatggt    420

tactaatctg gatgacagta actgggcagc tgcattttca tcacagcgtt ccgggctgtt    480

cacaaacaca gagccccaca gtataacaga agatgtaact atcagtgctg ttatgttacg    540

tgaggatgat cctggagaag ctgcatccat gagtatgttt tctgatttcc tgcagtcttt    600

tctgaagcac tcttcgagta cagtttttga tcttgtggaa gagtatgaaa acatctgtgg    660

tagtcaggtg aatatactga gtaaaatagt gagtcgagca acacctggac ttcaaaaatt    720

ttcaaaaaca gccagtatgc tctggcttct tcaacaggag atggtcacat ggaggctgct    780

ggcttctttg tatagagaca gaatacagtc tgcattagaa gaggaaagtg tattcgcagt    840

tactgctgtt aatgccagtg aaaaaacagt tgtggaagcg ttatttcaga gggattcact    900

tgttcgacaa agtcagctgg tggtagattg gttagagagt attgccaaag atgaaattgg    960

agaattttct gataatattg agttttatgc aaaatcagta tattgggaaa atactctgca   1020

taccttaaaa caacggcagc tgacttctta cgttggaagt gttcgtccgc ttgtcactga   1080

attggaccct gatgctccca taagacagaa aatgcccctt gatgatctgg atagagaaga   1140

tgaagttaga ttactcaaat atctctttac tctaatccgt gctggaatga cagaagaggc   1200

acaacgactc tgtaaacgct gtggtcaagc atggagagct gcaacacttg aaggctggaa   1260

actgtaccat gaccctaatg ttaatggagg aacagaatta gaacctgttg aagggaatcc   1320

atatagacgc atttggaaaa taagttgctg gagaatggca gaagatgagc tttttaatag   1380

atacgagaga gcaatttatg cagctttaag tgggaatctt aagcagctgc ttcctgtctg   1440

tgacacctgg gaagacacag tttgggccta cttccgggtg atggtggaca gtctggtaga   1500

acaggagatc cagacatcag tagcaactct ggatgaaact gaagaactcc ctagagaata   1560

tctgggagca aactggacgt tagaaaaggt ttttgaggaa cttcaagcta ctgacaaaaa   1620

gagagttctg gaagagaatc aagaacatta tcatatagtt caaaagtttc ttatcctggg   1680

agacattgat ggtttgatgg atgagtttag caaatggctt tccaaaagca gaaacaatct   1740

acctggacac ctgcttcgct ttatgactca ccttattttg tttttccgta ctctgggact   1800

acagaccaag gaggaagttt ctattgaagt tttaaagaca tacatacagc ttttaataag   1860

agagaaacat acaaatctta tagcatttta tacctgtcat ttgcctcaag acctagctgt   1920

tgcccagtat gcattatttt tggaaagtgt tacagaattt gaacagcgcc accattgcct   1980

ggagttggct aaagaagcag atttggatgt tgcaacaata acaaaaactg tagttgagaa   2040

tattcgaaag aaagataatg gtgaatttag tcatcatgac ctggccccag ccctagatac   2100

tggcactact gaggaggatc gtttaaaaat tgatgtaatt gactggttgg tatttgaccc   2160

agcgcagagg gcagaagcac tgaaacaagg caatgcaatt atgagaaaat tcttggcatc   2220

aaaaaagcac gaagctgcaa aagaagtatt tgtgaaaatt cctcaggatt ctatagcaga   2280

aatctataat cagtgcgagg aacaaggaat ggaaagtcca cttcctgctg aagatgataa   2340

tgctatccga gaacatttgt gcatcagagc ttatttggaa gcccatgaaa cctttaatga   2400

gtggtttaag catatgaatt cagttccaca aaaacctgct ttgatacctc aaccaacttt   2460

tactgagaaa gtggctcatg aacacaaaga aaagaaatat gaaatggatt ttggtatttg   2520

gaaagggcat ttggatgccc taactgctga tgtgaaggag aaaatgtata acgtcttgtt   2580

gtttgttgat ggagggtgga tggtggatgt tagagaggat gccaaagaag accatgaaag   2640

aacacatcaa atggtcttac tgagaaagct ttgtctgcca atgttgtgtt ttctgcttca   2700

tacgatattg cacagtactg gtcagtatca ggaatgccta cagttagcag atatggtatc   2760

ctctgagcgc cacaaactgt acctggtatt ttctaaggaa gagctaagga agttgctgca   2820

gaagctcaga gagtcctctc taatgctcct agaccaggga cttgacccat tagggtatga   2880

aattcagtta tagtttaatc tttgtaatct cactaatttt catgataaat gaagttttta   2940

ataaaatata cttgttatta gtaatttttt cttttgcatt accatgtaaa atttagacat   3000

ttgaattttg tacttttcag aatattatcg tgacactttc aacatgtagg gatatcagcg   3060

tttctctgtg tgcttgttaa taaaactata taaaaattaa aattttctgt ttttacaaat   3120

tcc                                                                 3123


<210>  8087
<211>  925
<212>  PRT
<213>  Homo sapiens

<400>  8087

Met Asp Arg Ser Gly Phe Gly Glu Ile Ser Ser Pro Val Ile Arg Glu 
1               5                   10                  15


Ala Glu Val Thr Arg Thr Ala Arg Lys Gln Ser Ala Gln Lys Arg Val 
            20                  25                  30


Leu Leu Gln Ala Ser Gln Asp Glu Asn Phe Gly Asn Thr Thr Pro Arg 
        35                  40                  45


Asn Gln Val Ile Pro Arg Thr Pro Ser Ser Phe Arg Gln Pro Phe Thr 
    50                  55                  60


Pro Thr Ser Arg Ser Leu Leu Arg Gln Pro Asp Ile Ser Cys Ile Leu 
65                  70                  75                  80


Gly Thr Gly Gly Lys Ser Pro Arg Leu Thr Gln Ser Ser Gly Phe Phe 
                85                  90                  95


Gly Asn Leu Ser Met Val Thr Asn Leu Asp Asp Ser Asn Trp Ala Ala 
            100                 105                 110


Ala Phe Ser Ser Gln Arg Ser Gly Leu Phe Thr Asn Thr Glu Pro His 
        115                 120                 125


Ser Ile Thr Glu Asp Val Thr Ile Ser Ala Val Met Leu Arg Glu Asp 
    130                 135                 140


Asp Pro Gly Glu Ala Ala Ser Met Ser Met Phe Ser Asp Phe Leu Gln 
145                 150                 155                 160


Ser Phe Leu Lys His Ser Ser Ser Thr Val Phe Asp Leu Val Glu Glu 
                165                 170                 175


Tyr Glu Asn Ile Cys Gly Ser Gln Val Asn Ile Leu Ser Lys Ile Val 
            180                 185                 190


Ser Arg Ala Thr Pro Gly Leu Gln Lys Phe Ser Lys Thr Ala Ser Met 
        195                 200                 205


Leu Trp Leu Leu Gln Gln Glu Met Val Thr Trp Arg Leu Leu Ala Ser 
    210                 215                 220


Leu Tyr Arg Asp Arg Ile Gln Ser Ala Leu Glu Glu Glu Ser Val Phe 
225                 230                 235                 240


Ala Val Thr Ala Val Asn Ala Ser Glu Lys Thr Val Val Glu Ala Leu 
                245                 250                 255


Phe Gln Arg Asp Ser Leu Val Arg Gln Ser Gln Leu Val Val Asp Trp 
            260                 265                 270


Leu Glu Ser Ile Ala Lys Asp Glu Ile Gly Glu Phe Ser Asp Asn Ile 
        275                 280                 285


Glu Phe Tyr Ala Lys Ser Val Tyr Trp Glu Asn Thr Leu His Thr Leu 
    290                 295                 300


Lys Gln Arg Gln Leu Thr Ser Tyr Val Gly Ser Val Arg Pro Leu Val 
305                 310                 315                 320


Thr Glu Leu Asp Pro Asp Ala Pro Ile Arg Gln Lys Met Pro Leu Asp 
                325                 330                 335


Asp Leu Asp Arg Glu Asp Glu Val Arg Leu Leu Lys Tyr Leu Phe Thr 
            340                 345                 350


Leu Ile Arg Ala Gly Met Thr Glu Glu Ala Gln Arg Leu Cys Lys Arg 
        355                 360                 365


Cys Gly Gln Ala Trp Arg Ala Ala Thr Leu Glu Gly Trp Lys Leu Tyr 
    370                 375                 380


His Asp Pro Asn Val Asn Gly Gly Thr Glu Leu Glu Pro Val Glu Gly 
385                 390                 395                 400


Asn Pro Tyr Arg Arg Ile Trp Lys Ile Ser Cys Trp Arg Met Ala Glu 
                405                 410                 415


Asp Glu Leu Phe Asn Arg Tyr Glu Arg Ala Ile Tyr Ala Ala Leu Ser 
            420                 425                 430


Gly Asn Leu Lys Gln Leu Leu Pro Val Cys Asp Thr Trp Glu Asp Thr 
        435                 440                 445


Val Trp Ala Tyr Phe Arg Val Met Val Asp Ser Leu Val Glu Gln Glu 
    450                 455                 460


Ile Gln Thr Ser Val Ala Thr Leu Asp Glu Thr Glu Glu Leu Pro Arg 
465                 470                 475                 480


Glu Tyr Leu Gly Ala Asn Trp Thr Leu Glu Lys Val Phe Glu Glu Leu 
                485                 490                 495


Gln Ala Thr Asp Lys Lys Arg Val Leu Glu Glu Asn Gln Glu His Tyr 
            500                 505                 510


His Ile Val Gln Lys Phe Leu Ile Leu Gly Asp Ile Asp Gly Leu Met 
        515                 520                 525


Asp Glu Phe Ser Lys Trp Leu Ser Lys Ser Arg Asn Asn Leu Pro Gly 
    530                 535                 540


His Leu Leu Arg Phe Met Thr His Leu Ile Leu Phe Phe Arg Thr Leu 
545                 550                 555                 560


Gly Leu Gln Thr Lys Glu Glu Val Ser Ile Glu Val Leu Lys Thr Tyr 
                565                 570                 575


Ile Gln Leu Leu Ile Arg Glu Lys His Thr Asn Leu Ile Ala Phe Tyr 
            580                 585                 590


Thr Cys His Leu Pro Gln Asp Leu Ala Val Ala Gln Tyr Ala Leu Phe 
        595                 600                 605


Leu Glu Ser Val Thr Glu Phe Glu Gln Arg His His Cys Leu Glu Leu 
    610                 615                 620


Ala Lys Glu Ala Asp Leu Asp Val Ala Thr Ile Thr Lys Thr Val Val 
625                 630                 635                 640


Glu Asn Ile Arg Lys Lys Asp Asn Gly Glu Phe Ser His His Asp Leu 
                645                 650                 655


Ala Pro Ala Leu Asp Thr Gly Thr Thr Glu Glu Asp Arg Leu Lys Ile 
            660                 665                 670


Asp Val Ile Asp Trp Leu Val Phe Asp Pro Ala Gln Arg Ala Glu Ala 
        675                 680                 685


Leu Lys Gln Gly Asn Ala Ile Met Arg Lys Phe Leu Ala Ser Lys Lys 
    690                 695                 700


His Glu Ala Ala Lys Glu Val Phe Val Lys Ile Pro Gln Asp Ser Ile 
705                 710                 715                 720


Ala Glu Ile Tyr Asn Gln Cys Glu Glu Gln Gly Met Glu Ser Pro Leu 
                725                 730                 735


Pro Ala Glu Asp Asp Asn Ala Ile Arg Glu His Leu Cys Ile Arg Ala 
            740                 745                 750


Tyr Leu Glu Ala His Glu Thr Phe Asn Glu Trp Phe Lys His Met Asn 
        755                 760                 765


Ser Val Pro Gln Lys Pro Ala Leu Ile Pro Gln Pro Thr Phe Thr Glu 
    770                 775                 780


Lys Val Ala His Glu His Lys Glu Lys Lys Tyr Glu Met Asp Phe Gly 
785                 790                 795                 800


Ile Trp Lys Gly His Leu Asp Ala Leu Thr Ala Asp Val Lys Glu Lys 
                805                 810                 815


Met Tyr Asn Val Leu Leu Phe Val Asp Gly Gly Trp Met Val Asp Val 
            820                 825                 830


Arg Glu Asp Ala Lys Glu Asp His Glu Arg Thr His Gln Met Val Leu 
        835                 840                 845


Leu Arg Lys Leu Cys Leu Pro Met Leu Cys Phe Leu Leu His Thr Ile 
    850                 855                 860


Leu His Ser Thr Gly Gln Tyr Gln Glu Cys Leu Gln Leu Ala Asp Met 
865                 870                 875                 880


Val Ser Ser Glu Arg His Lys Leu Tyr Leu Val Phe Ser Lys Glu Glu 
                885                 890                 895


Leu Arg Lys Leu Leu Gln Lys Leu Arg Glu Ser Ser Leu Met Leu Leu 
            900                 905                 910


Asp Gln Gly Leu Asp Pro Leu Gly Tyr Glu Ile Gln Leu 
        915                 920                 925


<210>  8088
<211>  712
<212>  DNA
<213>  Homo sapiens

<400>  8088
agggacagac tgcttccggg tcgaagggct tgcttccgga gagcgggaag gctaaaacgc     60

ggtagctaaa ctgcagccaa ctttggttgt gtgtggaaaa ggctttagcc atggacagga    120

gtggctttgg agagatatca tcccctgtaa tccgggaggc agaggtgaca cggactgcac    180

ggaaacagag tgctcagaaa agagttttac ttcaggcatc tcaagatgaa aattttggta    240

atactacacc aagaaaccag gttatccctc gaactcctag ctcatttcga cagcctttta    300

ccccaacaag ccgaagctta ctaaggcagc cagatatttc ctgcattctt ggaacaggag    360

ggaagtcgcc ccgacttacg cagtcttcag ggttctttgg aaatctctcc atggttacta    420

atctggatga cagtaactgg gcagctgcat tttcatcaca gcgttccggg ctgttcacaa    480

acacagagcc ccacagtata acagaagatg taactatcag tgctgttatg ttacgtgagg    540

atgatcctgg agaagctgca tccatgagta tgttttctga tttcctgcag tcttttctga    600

agcactcttc gagtacagtt tttgatcttg tggaagagta tgaaaacatc tgtggtagtc    660

agagacagaa tacagtctgc attagaagag gaaagtgtat tcgcagttac tg            712


<210>  8089
<211>  199
<212>  PRT
<213>  Homo sapiens

<400>  8089

Met Asp Arg Ser Gly Phe Gly Glu Ile Ser Ser Pro Val Ile Arg Glu 
1               5                   10                  15


Ala Glu Val Thr Arg Thr Ala Arg Lys Gln Ser Ala Gln Lys Arg Val 
            20                  25                  30


Leu Leu Gln Ala Ser Gln Asp Glu Asn Phe Gly Asn Thr Thr Pro Arg 
        35                  40                  45


Asn Gln Val Ile Pro Arg Thr Pro Ser Ser Phe Arg Gln Pro Phe Thr 
    50                  55                  60


Pro Thr Ser Arg Ser Leu Leu Arg Gln Pro Asp Ile Ser Cys Ile Leu 
65                  70                  75                  80


Gly Thr Gly Gly Lys Ser Pro Arg Leu Thr Gln Ser Ser Gly Phe Phe 
                85                  90                  95


Gly Asn Leu Ser Met Val Thr Asn Leu Asp Asp Ser Asn Trp Ala Ala 
            100                 105                 110


Ala Phe Ser Ser Gln Arg Ser Gly Leu Phe Thr Asn Thr Glu Pro His 
        115                 120                 125


Ser Ile Thr Glu Asp Val Thr Ile Ser Ala Val Met Leu Arg Glu Asp 
    130                 135                 140


Asp Pro Gly Glu Ala Ala Ser Met Ser Met Phe Ser Asp Phe Leu Gln 
145                 150                 155                 160


Ser Phe Leu Lys His Ser Ser Ser Thr Val Phe Asp Leu Val Glu Glu 
                165                 170                 175


Tyr Glu Asn Ile Cys Gly Ser Gln Arg Gln Asn Thr Val Cys Ile Arg 
            180                 185                 190


Arg Gly Lys Cys Ile Arg Ser 
        195


<210>  8090
<211>  2709
<212>  DNA
<213>  Homo sapiens

<400>  8090
agggacagac tgcttccggg tcgaagggct tgcttccgga gagcgggaag gctaaaacgc     60

ggtagctaaa ctgcagccaa ctttggttgt gtgtggaaaa ggctttagcc atggacagga    120

gtggctttgg agagatatca tcccctgtaa tccgggaggc agaggtgaca cggactgcac    180

ggaaacagag tgctcagaaa agagttttac ttcaggcatc tcaagatgaa aattttggta    240

atactacacc aagaaaccag gttatccctc gaactcctag ctcatttcga cagcctttta    300

ccccaacaag ccgaagctta ctaaggcagc cagatatttc ctgcattctt ggaacaggag    360

ggaagtcgcc ccgacttacg cagtcttcag ggttctttgg aaatctctcc atgcatccat    420

gagtatgttt tctgatttcc tgcagtcttt tctgaagcac tcttcgagta cagtttttga    480

tcttgtggaa gagtatgaaa acatctgtgg tagtcaggtg aatatactga gtaaaatagt    540

gagtcgagca acacctggac ttcaaaaatt ttcaaaaaca gccagtatgc tctggcttct    600

tcaacaggag atggtcacat ggaggctgct ggcttctttg tatagagaca gaatacagtc    660

tgcattagaa gaggaaagtg tattcgcagt tactgctgtt aatgccagtg aaaaaacagt    720

tgtggaagcg ttatttcaga gggattcact tgttcgacaa agtcagctgg tggtagattg    780

gttagagagt attgccaaag atgaaattgg agaattttct gataatattg agttttatgc    840

aaaatcagta tattgggaaa atactctgca taccttaaaa caacggcagc tgacttctta    900

cgttggaagt gttcgtccgc ttgtcactga attggaccct gatgctccca taagacagaa    960

aatgcccctt gatgatctgg atagagaaga tgaagttaga ttactcaaat atctctttac   1020

tctaatccgt gctggaatga cagaagaggc acaacgactc tgtaaacgct gtggtcaagc   1080

atggagagct gcaacacttg aaggctggaa actgtaccat gaccctaatg ttaatggagg   1140

aacagaatta gaacctgttg aagggaatcc atatagacgc atttggaaaa taagttgctg   1200

gagaatggca gaagatgagc tttttaatag atacgagaga gcaatttatg cagctttaag   1260

tgggaatctt aagcagctgc ttcctgtctg tgacacctgg gaagacacag tttgggccta   1320

cttccgggtg atggtggaca gtctggtaga acaggagatc cagacatcag tagcaactct   1380

ggatgaaact gaagaactcc ctagagaata tctgggagca aactggacgt tagaaaaggt   1440

ttttgaggaa cttcaagcta ctgacaaaaa gagagttctg gaagagaatc aagaacatta   1500

tcatatagtt caaaagtttc ttatcctggg agacattgat ggtttgatgg atgagtttag   1560

caaatggctt tccaaaagca gaaacaatct acctggacac ctgcttcgct ttatgactca   1620

ccttattttg tttttccgta ctctgggact acagaccaag gaggaagttt ctattgaagt   1680

tttaaagaca tacatacagg aggatcgttt aaaaattgat gtaattgact ggttggtatt   1740

tgacccagcg cagagggcag aagcactgaa acaaggcaat gcaattatga gaaaattctt   1800

ggcatcaaaa aagcacgaag ctgcaaaaga agtatttgtg aaaattcctc aggattctat   1860

agcagaaatc tataatcagt gcgaggaaca aggaatggaa agtccacttc ctgctgaaga   1920

tgataatgct atccgagaac atttgtgcat cagagcttat ttggaagccc atgaaacctt   1980

taatgagtgg tttaagcata tgaattcagt tccacaaaaa cctgctttga tacctcaacc   2040

aacttttact gagaaagtgg ctcatgaaca caaagaaaag aaatatgaaa tggattttgg   2100

tatttggaaa gggcatttgg atgccctaac tgctgatgtg aaggagaaaa tgtataacgt   2160

cttgttgttt gttgatggag ggtggatggt ggatgttaga gaggatgcca aagaagacca   2220

tgaaagaaca catcaaatgg tcttactgag aaagctttgt ctgccaatgt tgtgttttct   2280

gcttcatacg atattgcaca gtactggtca gtatcaggaa tgcctacagt tagcagatat   2340

ggtatcctct gagcgccaca aactgtacct ggtattttct aaggaagagc taaggaagtt   2400

gctgcagaag ctcagagagt cctctctaat gctcctagac cagggacttg acccattagg   2460

gtatgaaatt cagttatagt ttaatctttg taatctcact aattttcatg ataaatgaag   2520

tttttaataa aatatacttg ttattagtaa ttttttcttt tgcattacca tgtaaaattt   2580

agacatttga attttgtact tttcagaata ttatcgtgac actttcaaca tgtagggata   2640

tcagcgtttc tctgtgtgct tgttaataaa actatataaa aattaaaatt ttctgttttt   2700

acaaattcc                                                           2709


<210>  8091
<211>  686
<212>  PRT
<213>  Homo sapiens

<400>  8091

Met Ser Met Phe Ser Asp Phe Leu Gln Ser Phe Leu Lys His Ser Ser 
1               5                   10                  15


Ser Thr Val Phe Asp Leu Val Glu Glu Tyr Glu Asn Ile Cys Gly Ser 
            20                  25                  30


Gln Val Asn Ile Leu Ser Lys Ile Val Ser Arg Ala Thr Pro Gly Leu 
        35                  40                  45


Gln Lys Phe Ser Lys Thr Ala Ser Met Leu Trp Leu Leu Gln Gln Glu 
    50                  55                  60


Met Val Thr Trp Arg Leu Leu Ala Ser Leu Tyr Arg Asp Arg Ile Gln 
65                  70                  75                  80


Ser Ala Leu Glu Glu Glu Ser Val Phe Ala Val Thr Ala Val Asn Ala 
                85                  90                  95


Ser Glu Lys Thr Val Val Glu Ala Leu Phe Gln Arg Asp Ser Leu Val 
            100                 105                 110


Arg Gln Ser Gln Leu Val Val Asp Trp Leu Glu Ser Ile Ala Lys Asp 
        115                 120                 125


Glu Ile Gly Glu Phe Ser Asp Asn Ile Glu Phe Tyr Ala Lys Ser Val 
    130                 135                 140


Tyr Trp Glu Asn Thr Leu His Thr Leu Lys Gln Arg Gln Leu Thr Ser 
145                 150                 155                 160


Tyr Val Gly Ser Val Arg Pro Leu Val Thr Glu Leu Asp Pro Asp Ala 
                165                 170                 175


Pro Ile Arg Gln Lys Met Pro Leu Asp Asp Leu Asp Arg Glu Asp Glu 
            180                 185                 190


Val Arg Leu Leu Lys Tyr Leu Phe Thr Leu Ile Arg Ala Gly Met Thr 
        195                 200                 205


Glu Glu Ala Gln Arg Leu Cys Lys Arg Cys Gly Gln Ala Trp Arg Ala 
    210                 215                 220


Ala Thr Leu Glu Gly Trp Lys Leu Tyr His Asp Pro Asn Val Asn Gly 
225                 230                 235                 240


Gly Thr Glu Leu Glu Pro Val Glu Gly Asn Pro Tyr Arg Arg Ile Trp 
                245                 250                 255


Lys Ile Ser Cys Trp Arg Met Ala Glu Asp Glu Leu Phe Asn Arg Tyr 
            260                 265                 270


Glu Arg Ala Ile Tyr Ala Ala Leu Ser Gly Asn Leu Lys Gln Leu Leu 
        275                 280                 285


Pro Val Cys Asp Thr Trp Glu Asp Thr Val Trp Ala Tyr Phe Arg Val 
    290                 295                 300


Met Val Asp Ser Leu Val Glu Gln Glu Ile Gln Thr Ser Val Ala Thr 
305                 310                 315                 320


Leu Asp Glu Thr Glu Glu Leu Pro Arg Glu Tyr Leu Gly Ala Asn Trp 
                325                 330                 335


Thr Leu Glu Lys Val Phe Glu Glu Leu Gln Ala Thr Asp Lys Lys Arg 
            340                 345                 350


Val Leu Glu Glu Asn Gln Glu His Tyr His Ile Val Gln Lys Phe Leu 
        355                 360                 365


Ile Leu Gly Asp Ile Asp Gly Leu Met Asp Glu Phe Ser Lys Trp Leu 
    370                 375                 380


Ser Lys Ser Arg Asn Asn Leu Pro Gly His Leu Leu Arg Phe Met Thr 
385                 390                 395                 400


His Leu Ile Leu Phe Phe Arg Thr Leu Gly Leu Gln Thr Lys Glu Glu 
                405                 410                 415


Val Ser Ile Glu Val Leu Lys Thr Tyr Ile Gln Glu Asp Arg Leu Lys 
            420                 425                 430


Ile Asp Val Ile Asp Trp Leu Val Phe Asp Pro Ala Gln Arg Ala Glu 
        435                 440                 445


Ala Leu Lys Gln Gly Asn Ala Ile Met Arg Lys Phe Leu Ala Ser Lys 
    450                 455                 460


Lys His Glu Ala Ala Lys Glu Val Phe Val Lys Ile Pro Gln Asp Ser 
465                 470                 475                 480


Ile Ala Glu Ile Tyr Asn Gln Cys Glu Glu Gln Gly Met Glu Ser Pro 
                485                 490                 495


Leu Pro Ala Glu Asp Asp Asn Ala Ile Arg Glu His Leu Cys Ile Arg 
            500                 505                 510


Ala Tyr Leu Glu Ala His Glu Thr Phe Asn Glu Trp Phe Lys His Met 
        515                 520                 525


Asn Ser Val Pro Gln Lys Pro Ala Leu Ile Pro Gln Pro Thr Phe Thr 
    530                 535                 540


Glu Lys Val Ala His Glu His Lys Glu Lys Lys Tyr Glu Met Asp Phe 
545                 550                 555                 560


Gly Ile Trp Lys Gly His Leu Asp Ala Leu Thr Ala Asp Val Lys Glu 
                565                 570                 575


Lys Met Tyr Asn Val Leu Leu Phe Val Asp Gly Gly Trp Met Val Asp 
            580                 585                 590


Val Arg Glu Asp Ala Lys Glu Asp His Glu Arg Thr His Gln Met Val 
        595                 600                 605


Leu Leu Arg Lys Leu Cys Leu Pro Met Leu Cys Phe Leu Leu His Thr 
    610                 615                 620


Ile Leu His Ser Thr Gly Gln Tyr Gln Glu Cys Leu Gln Leu Ala Asp 
625                 630                 635                 640


Met Val Ser Ser Glu Arg His Lys Leu Tyr Leu Val Phe Ser Lys Glu 
                645                 650                 655


Glu Leu Arg Lys Leu Leu Gln Lys Leu Arg Glu Ser Ser Leu Met Leu 
            660                 665                 670


Leu Asp Gln Gly Leu Asp Pro Leu Gly Tyr Glu Ile Gln Leu 
        675                 680                 685


<210>  8092
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  8092
ccgggtcgaa gggcttgctt ccggagagcg ggaaggctaa aacgcggtag ctaaactgca     60

gccaactttg gttgtgtgtg gaaaaggctt tagccatgga caggagtggc tttggagaga    120

tatcatcccc tgtaatccgg gaggcagagg tgacacggac tgcacggaaa cagagtgctc    180

agaaaagagt tttacttcag gcatctcaag atgaaaattt tggtaatact acaccaagaa    240

accaggttat ccctcgaact cctagctcat ttcgacagcc ttgtaagatt ttttgctttt    300

aaagcattta ataataacgg taattataat agcaactaac atttattgta acataattag    360

tatagtattt ggttacgata tcaataagca ctaataataa tgattgcagt tattattcgt    420

ttgaactctt gccatgtaca aggtactgta ctttccataa acacacggta actatgacat    480

gggtattgtt ggccctgttt taccaaaact gaaagtgaga cttagagaag ttaactaata    540

tatacaataa gtatgtaaat aggctggatg cag                                 573


<210>  8093
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  8093

Met Asp Arg Ser Gly Phe Gly Glu Ile Ser Ser Pro Val Ile Arg Glu 
1               5                   10                  15


Ala Glu Val Thr Arg Thr Ala Arg Lys Gln Ser Ala Gln Lys Arg Val 
            20                  25                  30


Leu Leu Gln Ala Ser Gln Asp Glu Asn Phe Gly Asn Thr Thr Pro Arg 
        35                  40                  45


Asn Gln Val Ile Pro Arg Thr Pro Ser Ser Phe Arg Gln Pro Cys Lys 
    50                  55                  60


Ile Phe Cys Phe 
65


<210>  8094
<211>  729
<212>  DNA
<213>  Homo sapiens

<400>  8094
gtagaatatc tttaaaaaaa aaactctgat attccttttt ctttttttcc cctttaataa     60

ataggaggat cgtttaaaaa ttgatgtaat tgactggttg gtatttgacc cagcgcagag    120

ggcagaagca ctgaaacaag gcaatgcaat tatgagaaaa ttcttgggta tagtatattt    180

ttatgcagct tcaaactcct gggctccatt cttcttccta cctcagcctc ccaactactc    240

gggaggctga ggcaggagaa tcgcgtgaac ccggcaggcg gagcttgcag tgagctgaga    300

tcgcgccact gcactccagc ctgggcgaca gagcgagact ccgtctcaaa aaaaaaaaaa    360

aaagtggaaa tatccctagt ggaaataatc cgtctgtttt acatatttac cggctatttc    420

aaagcttttg ttcattcaga tgagaaaaat gtcttcagtt gtagcagagc tgtttatttg    480

cttttccttg tagcaatttg ctgggtctgt cagccattac cctggatagt tgctggcagc    540

ccgcccgcta gtatcggaat tcattataat tagcagaaga gattgtctgc agcacactct    600

gatattatgg cagcaaaagg atttagtaaa agcaagtctg ggtccatcct gtgagataag    660

aaagtaacct gctgcttttc gggcaacaag gagtcagaag ccaggggcac ccggcctctt    720

taacataga                                                            729


<210>  8095
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  8095

Met Gln Leu Gln Thr Pro Gly Leu His Ser Ser Ser Tyr Leu Ser Leu 
1               5                   10                  15


Pro Thr Thr Arg Glu Ala Glu Ala Gly Glu Ser Arg Glu Pro Gly Arg 
            20                  25                  30


Arg Ser Leu Gln 
        35


<210>  8096
<211>  4460
<212>  DNA
<213>  Homo sapiens

<400>  8096
tgtgattggc tgttgccatg gatacgcttt gtgtagcggc tatgggcgct gtcttacaac     60

aaagccaagg aatctcgctg ctgagggcag ttctgtgctt tattatgaag aataatggac    120

gatgatgatg caaagctcaa agcagaaata gaagctgaat tggataaact cagcatttcc    180

tccttggaaa aagaagacat tgagagtgat gcaaaatcag aaacccagag tgatgatagt    240

gatacagatt cagttgaatt accagaatca gttcttcact gtattaacat cataaagaac    300

aggagtaaag ctgttgaaga gctcattctt caggacctgg aagatactga tattttaagc    360

tgtagttatg gagcagtttc taataatcat atgcatttaa gaacaggact atcaactgaa    420

tatgaagaaa gttcagagca attaattaag atattatctg aaatagaaaa agaagaattt    480

atgagaagta aaaccgattg tgccactcct gattttgttc ctgagcctag tcctcatgac    540

ttgcctatgg atgaacatgt tttaccagat gatgctgata taaattttgg atactgtgaa    600

gtggaagaaa aatgtagaca gtcttttgag gcttggcaag agaaacagaa ggaattagaa    660

gataaagaga aacaaactct caaagctcag agggatagag aagaaaaaca atttcaagaa    720

gaagaagaaa agcgacattg ctggatgaaa caatttaaag ttgaaaagaa gaaattagag    780

aacattcaga agcaagaaca ggacaagatg aatgatgaac tctataaaga agagaaaatt    840

tggaaagaga aatttaaaca gcatgaggag tatattagaa acttgcattt acaaatggaa    900

gaagaaagaa caagatttaa agaccaacaa gaaaaagaaa aaaattcttt gttaaaacag    960

cagaataatg cagctgttaa aattcaagct aaatataaag catttgttgc ctatcaaaaa   1020

tatggcccaa ttattaaaga gcaaattgaa agtaagaaaa ggaaagcaca agagtggaag   1080

gaaaaggaag caaaaatacg acaaaaggag gaagaaaatc gaaaaagatt agaggaggaa   1140

caaaggataa aagaagagag aaaaaagcaa aaggaagagg aaaggaaaag gagagaaaaa   1200

gaatatgaag aaaaaaagaa tattgtgaaa caggaaagag agcaactaat aagcaaggaa   1260

aaaataatat taagagaaga tgcaagccaa cagctaataa taagtagtgc attaaagaag   1320

agcggatata ataacaaaca tttaagtctt gaagatattt caaatgataa gggtgatata   1380

gccaaaaatc tagtggatga aaattcaaag aagcaggaag atgttctcct ttggctagtt   1440

gaggaatcaa atatgaaaga aaatgtagat agacagacta tattaaaaga atcaatacaa   1500

gtaaagttaa aagaatctat atcaagccaa acaattctgg cagattttaa aatggaagaa   1560

aaaaatgaaa acctagcaaa aaaacgatgt tcagaagaat tggtcaagca agaaagaaaa   1620

tatgaaaata cagataacaa aactgaattg ggaaactctg atctaaaagg aaatctgaaa   1680

gaacagtttc cattgcaaga attaaagtct gatgcacaaa aagaagaaaa aatcatgaaa   1740

catgtcataa atgagaatac aggacaaaaa acccagataa tattaggaca taaccaagaa   1800

atcagtgagg tgaaaaccaa tgaagagcag aaaataatca aagataatca gcagaaaaag   1860

atacaaaaag tagaaaaaga agagatacaa gaacagaatg gattattata taaagataag   1920

gatactttag ttatttcagt gaaacaaaga tcactctcac taacatcaga aaattccaaa   1980

gatgtaagag aaaacgtaat attacaagaa aaagaaattt attcaaaatc caaagaaatt   2040

gaggagaacc caaaagacaa tgcttggaat agtggcattg tgatttttaa cacaactgat   2100

accatgataa atatagaagg caaaagaaat gaccaagatt atgtgttagg tagacatgct   2160

ccttgtgagg gcttgagtaa ctataatgca gaaagctcca tggtatctaa agaagtcaac   2220

tctcttaaat ctgagattag aaatatttca gaaaaatgcc atgaaaatgc acctgaacct   2280

gatagcatga cctgctgtgt atcagagtca acccttctat attctattga agaaaggaga   2340

ctagcctgga taaaatcatt taaaccttgg cttgaaattt tcaagcaaaa tcaacaaaag   2400

aaaattgtta gaagaaagag acctgtgaaa tgcccagcca acatgacacc cgctttggat   2460

aaactggaaa ttcttcgatg tggcccttgg gatactttac agcaggttac aacagttaca   2520

tttcaagatt tgccaggctg tgttctctcc acactggcag agtgtacaaa tcttcagttt   2580

ctatcccttc gacgctgtgg attaacttct ttgcacagcc tgagtaattg taaaaaactt   2640

aagtacattg atgcacagga aaaccatatt gaggctattg agtgtgaaaa tttggaaaat   2700

ctctgtgttg ttcttcttaa taaaaatcaa ctgacttctc ttcatggttt ggatggctgt   2760

actaatattc agtgtcttga actttcatat aataaaatta ctcgaattgg atattccttc   2820

tttctggaag aaaaacttgt tgacaatgca gggttctgcc atcacttggg cacctccact   2880

tcttacttat ccctggcaca agtctggatt ccaactggat tatgttggtc ctggatacct   2940

attacctcac ttacaaaaaa ttcagattgt aatttcctta tctcccactt atactggaat   3000

tgtggtttag aatctttgaa aaatcttcaa caactaattt tggaccacaa tcagttaatt   3060

aatacaaaag gtctttgtga tacacctacc attgtatacc tagattgctc ccataatcat   3120

cttactgatg tagagggcgt tgaaaattgt ggattgctcc aaatattgaa gttacaggga   3180

aattatctga gtgagcttcc atccttggag aatcttgttt tactaagaga attgcacttg   3240

gatgataaca gcatttcaac tgtggaagca ttttcttcat actggctgcc tttactacaa   3300

aatattacta tctctcaaaa cagcttgact aaaatcgtac cactttttca ttttgtttca   3360

ttggaaaagc tagatgtcag ccacaattgt ctttctgatc ttaaaagtgc cataaaatgg   3420

tttgatgcat gctattctct ccatgaattg tctcttactg gaaacccact tcttcaagaa   3480

acaaactgga gggattctct acttaaagtg ttgcctgctc tgagaatcct caatggcaat   3540

atactaaact ctaattcaga aagccgcact gaagaacaca atcaactggg atcagcaggt   3600

ttcctggcac tttgtcagtc tcagattcga gaattcaact tgctaattga aaattatata   3660

actggaaaag gagatgtatt taccttggat actgcagaaa atctctgtca ttattttaag   3720

aaattgatga tacttagtac tgaataccga catgcacacg aacgagggga tgtaactatc   3780

accaagaaag atgaatcaga agcccagaaa aatcatttgg cccctacaaa cagtgacagc   3840

actctgcaaa atggagtctt ctactcttgt gcacgtgaag gtgagccaga ctcaccagat   3900

attcctgaga aatggatgga ctctgtctcc agccactccc cattaagcaa atccgccaca   3960

tgtgaaaata tggaaggaag acatcaggaa atattagtat gtcagaagag agaagacagc   4020

aaggcaagca gtattcccac cataagaatc ccatttaagg aagtagtaat gacaaattct   4080

ttgctgagga atcaccaaaa tattgagcct agtgaaaaaa tgtaagatat ataaataatg   4140

tttcttttat agatgtatgt ttactccttt tgatggatga tattagtcaa tggtacctag   4200

taatttgctg aaggattcaa atcacaatca tatttcatac cgattccatt atgttttcgt   4260

gaggtgcatt atgttttcat gaggtgcaca aatcattaat tatagtgcat attaatttga   4320

ttaaattctc atttaatttc tagtagtatt taaatgagta aatgtgagtt tttttctgcc   4380

ttgtaatttc taaataatta atatgtttta aggagaaata aaatatcaca gtctaaaaat   4440

aataaaaaca ttttctgagt                                               4460


<210>  8097
<211>  1336
<212>  PRT
<213>  Homo sapiens

<400>  8097

Met Asp Asp Asp Asp Ala Lys Leu Lys Ala Glu Ile Glu Ala Glu Leu 
1               5                   10                  15


Asp Lys Leu Ser Ile Ser Ser Leu Glu Lys Glu Asp Ile Glu Ser Asp 
            20                  25                  30


Ala Lys Ser Glu Thr Gln Ser Asp Asp Ser Asp Thr Asp Ser Val Glu 
        35                  40                  45


Leu Pro Glu Ser Val Leu His Cys Ile Asn Ile Ile Lys Asn Arg Ser 
    50                  55                  60


Lys Ala Val Glu Glu Leu Ile Leu Gln Asp Leu Glu Asp Thr Asp Ile 
65                  70                  75                  80


Leu Ser Cys Ser Tyr Gly Ala Val Ser Asn Asn His Met His Leu Arg 
                85                  90                  95


Thr Gly Leu Ser Thr Glu Tyr Glu Glu Ser Ser Glu Gln Leu Ile Lys 
            100                 105                 110


Ile Leu Ser Glu Ile Glu Lys Glu Glu Phe Met Arg Ser Lys Thr Asp 
        115                 120                 125


Cys Ala Thr Pro Asp Phe Val Pro Glu Pro Ser Pro His Asp Leu Pro 
    130                 135                 140


Met Asp Glu His Val Leu Pro Asp Asp Ala Asp Ile Asn Phe Gly Tyr 
145                 150                 155                 160


Cys Glu Val Glu Glu Lys Cys Arg Gln Ser Phe Glu Ala Trp Gln Glu 
                165                 170                 175


Lys Gln Lys Glu Leu Glu Asp Lys Glu Lys Gln Thr Leu Lys Ala Gln 
            180                 185                 190


Arg Asp Arg Glu Glu Lys Gln Phe Gln Glu Glu Glu Glu Lys Arg His 
        195                 200                 205


Cys Trp Met Lys Gln Phe Lys Val Glu Lys Lys Lys Leu Glu Asn Ile 
    210                 215                 220


Gln Lys Gln Glu Gln Asp Lys Met Asn Asp Glu Leu Tyr Lys Glu Glu 
225                 230                 235                 240


Lys Ile Trp Lys Glu Lys Phe Lys Gln His Glu Glu Tyr Ile Arg Asn 
                245                 250                 255


Leu His Leu Gln Met Glu Glu Glu Arg Thr Arg Phe Lys Asp Gln Gln 
            260                 265                 270


Glu Lys Glu Lys Asn Ser Leu Leu Lys Gln Gln Asn Asn Ala Ala Val 
        275                 280                 285


Lys Ile Gln Ala Lys Tyr Lys Ala Phe Val Ala Tyr Gln Lys Tyr Gly 
    290                 295                 300


Pro Ile Ile Lys Glu Gln Ile Glu Ser Lys Lys Arg Lys Ala Gln Glu 
305                 310                 315                 320


Trp Lys Glu Lys Glu Ala Lys Ile Arg Gln Lys Glu Glu Glu Asn Arg 
                325                 330                 335


Lys Arg Leu Glu Glu Glu Gln Arg Ile Lys Glu Glu Arg Lys Lys Gln 
            340                 345                 350


Lys Glu Glu Glu Arg Lys Arg Arg Glu Lys Glu Tyr Glu Glu Lys Lys 
        355                 360                 365


Asn Ile Val Lys Gln Glu Arg Glu Gln Leu Ile Ser Lys Glu Lys Ile 
    370                 375                 380


Ile Leu Arg Glu Asp Ala Ser Gln Gln Leu Ile Ile Ser Ser Ala Leu 
385                 390                 395                 400


Lys Lys Ser Gly Tyr Asn Asn Lys His Leu Ser Leu Glu Asp Ile Ser 
                405                 410                 415


Asn Asp Lys Gly Asp Ile Ala Lys Asn Leu Val Asp Glu Asn Ser Lys 
            420                 425                 430


Lys Gln Glu Asp Val Leu Leu Trp Leu Val Glu Glu Ser Asn Met Lys 
        435                 440                 445


Glu Asn Val Asp Arg Gln Thr Ile Leu Lys Glu Ser Ile Gln Val Lys 
    450                 455                 460


Leu Lys Glu Ser Ile Ser Ser Gln Thr Ile Leu Ala Asp Phe Lys Met 
465                 470                 475                 480


Glu Glu Lys Asn Glu Asn Leu Ala Lys Lys Arg Cys Ser Glu Glu Leu 
                485                 490                 495


Val Lys Gln Glu Arg Lys Tyr Glu Asn Thr Asp Asn Lys Thr Glu Leu 
            500                 505                 510


Gly Asn Ser Asp Leu Lys Gly Asn Leu Lys Glu Gln Phe Pro Leu Gln 
        515                 520                 525


Glu Leu Lys Ser Asp Ala Gln Lys Glu Glu Lys Ile Met Lys His Val 
    530                 535                 540


Ile Asn Glu Asn Thr Gly Gln Lys Thr Gln Ile Ile Leu Gly His Asn 
545                 550                 555                 560


Gln Glu Ile Ser Glu Val Lys Thr Asn Glu Glu Gln Lys Ile Ile Lys 
                565                 570                 575


Asp Asn Gln Gln Lys Lys Ile Gln Lys Val Glu Lys Glu Glu Ile Gln 
            580                 585                 590


Glu Gln Asn Gly Leu Leu Tyr Lys Asp Lys Asp Thr Leu Val Ile Ser 
        595                 600                 605


Val Lys Gln Arg Ser Leu Ser Leu Thr Ser Glu Asn Ser Lys Asp Val 
    610                 615                 620


Arg Glu Asn Val Ile Leu Gln Glu Lys Glu Ile Tyr Ser Lys Ser Lys 
625                 630                 635                 640


Glu Ile Glu Glu Asn Pro Lys Asp Asn Ala Trp Asn Ser Gly Ile Val 
                645                 650                 655


Ile Phe Asn Thr Thr Asp Thr Met Ile Asn Ile Glu Gly Lys Arg Asn 
            660                 665                 670


Asp Gln Asp Tyr Val Leu Gly Arg His Ala Pro Cys Glu Gly Leu Ser 
        675                 680                 685


Asn Tyr Asn Ala Glu Ser Ser Met Val Ser Lys Glu Val Asn Ser Leu 
    690                 695                 700


Lys Ser Glu Ile Arg Asn Ile Ser Glu Lys Cys His Glu Asn Ala Pro 
705                 710                 715                 720


Glu Pro Asp Ser Met Thr Cys Cys Val Ser Glu Ser Thr Leu Leu Tyr 
                725                 730                 735


Ser Ile Glu Glu Arg Arg Leu Ala Trp Ile Lys Ser Phe Lys Pro Trp 
            740                 745                 750


Leu Glu Ile Phe Lys Gln Asn Gln Gln Lys Lys Ile Val Arg Arg Lys 
        755                 760                 765


Arg Pro Val Lys Cys Pro Ala Asn Met Thr Pro Ala Leu Asp Lys Leu 
    770                 775                 780


Glu Ile Leu Arg Cys Gly Pro Trp Asp Thr Leu Gln Gln Val Thr Thr 
785                 790                 795                 800


Val Thr Phe Gln Asp Leu Pro Gly Cys Val Leu Ser Thr Leu Ala Glu 
                805                 810                 815


Cys Thr Asn Leu Gln Phe Leu Ser Leu Arg Arg Cys Gly Leu Thr Ser 
            820                 825                 830


Leu His Ser Leu Ser Asn Cys Lys Lys Leu Lys Tyr Ile Asp Ala Gln 
        835                 840                 845


Glu Asn His Ile Glu Ala Ile Glu Cys Glu Asn Leu Glu Asn Leu Cys 
    850                 855                 860


Val Val Leu Leu Asn Lys Asn Gln Leu Thr Ser Leu His Gly Leu Asp 
865                 870                 875                 880


Gly Cys Thr Asn Ile Gln Cys Leu Glu Leu Ser Tyr Asn Lys Ile Thr 
                885                 890                 895


Arg Ile Gly Tyr Ser Phe Phe Leu Glu Glu Lys Leu Val Asp Asn Ala 
            900                 905                 910


Gly Phe Cys His His Leu Gly Thr Ser Thr Ser Tyr Leu Ser Leu Ala 
        915                 920                 925


Gln Val Trp Ile Pro Thr Gly Leu Cys Trp Ser Trp Ile Pro Ile Thr 
    930                 935                 940


Ser Leu Thr Lys Asn Ser Asp Cys Asn Phe Leu Ile Ser His Leu Tyr 
945                 950                 955                 960


Trp Asn Cys Gly Leu Glu Ser Leu Lys Asn Leu Gln Gln Leu Ile Leu 
                965                 970                 975


Asp His Asn Gln Leu Ile Asn Thr Lys Gly Leu Cys Asp Thr Pro Thr 
            980                 985                 990


Ile Val Tyr Leu Asp Cys Ser His Asn His Leu Thr Asp Val Glu Gly 
        995                 1000                1005


Val Glu Asn Cys Gly Leu Leu Gln Ile Leu Lys Leu Gln Gly Asn Tyr 
    1010                1015                1020


Leu Ser Glu Leu Pro Ser Leu Glu Asn Leu Val Leu Leu Arg Glu Leu 
1025                1030                1035                1040


His Leu Asp Asp Asn Ser Ile Ser Thr Val Glu Ala Phe Ser Ser Tyr 
                1045                1050                1055


Trp Leu Pro Leu Leu Gln Asn Ile Thr Ile Ser Gln Asn Ser Leu Thr 
            1060                1065                1070


Lys Ile Val Pro Leu Phe His Phe Val Ser Leu Glu Lys Leu Asp Val 
        1075                1080                1085


Ser His Asn Cys Leu Ser Asp Leu Lys Ser Ala Ile Lys Trp Phe Asp 
    1090                1095                1100


Ala Cys Tyr Ser Leu His Glu Leu Ser Leu Thr Gly Asn Pro Leu Leu 
1105                1110                1115                1120


Gln Glu Thr Asn Trp Arg Asp Ser Leu Leu Lys Val Leu Pro Ala Leu 
                1125                1130                1135


Arg Ile Leu Asn Gly Asn Ile Leu Asn Ser Asn Ser Glu Ser Arg Thr 
            1140                1145                1150


Glu Glu His Asn Gln Leu Gly Ser Ala Gly Phe Leu Ala Leu Cys Gln 
        1155                1160                1165


Ser Gln Ile Arg Glu Phe Asn Leu Leu Ile Glu Asn Tyr Ile Thr Gly 
    1170                1175                1180


Lys Gly Asp Val Phe Thr Leu Asp Thr Ala Glu Asn Leu Cys His Tyr 
1185                1190                1195                1200


Phe Lys Lys Leu Met Ile Leu Ser Thr Glu Tyr Arg His Ala His Glu 
                1205                1210                1215


Arg Gly Asp Val Thr Ile Thr Lys Lys Asp Glu Ser Glu Ala Gln Lys 
            1220                1225                1230


Asn His Leu Ala Pro Thr Asn Ser Asp Ser Thr Leu Gln Asn Gly Val 
        1235                1240                1245


Phe Tyr Ser Cys Ala Arg Glu Gly Glu Pro Asp Ser Pro Asp Ile Pro 
    1250                1255                1260


Glu Lys Trp Met Asp Ser Val Ser Ser His Ser Pro Leu Ser Lys Ser 
1265                1270                1275                1280


Ala Thr Cys Glu Asn Met Glu Gly Arg His Gln Glu Ile Leu Val Cys 
                1285                1290                1295


Gln Lys Arg Glu Asp Ser Lys Ala Ser Ser Ile Pro Thr Ile Arg Ile 
            1300                1305                1310


Pro Phe Lys Glu Val Val Met Thr Asn Ser Leu Leu Arg Asn His Gln 
        1315                1320                1325


Asn Ile Glu Pro Ser Glu Lys Met 
    1330                1335


<210>  8098
<211>  712
<212>  DNA
<213>  Homo sapiens

<400>  8098
tcaaagacca gtagaaagag tttgctaaaa tctgaaaaag aaaaaaaaat ttcagaagaa     60

tggggcttta aggatatttc tactgctcag caaatgttga agagggcaca gaaaatgaaa    120

tcgaagaaac taaagaaaaa aatagattcc actgtgcgtc tagccttatt caaaaacaat    180

gaaaataaag tgtctcttcc aaaatcacca aagatggtac agcccagaag agatggttac    240

tttgaaggta tagaagaaga ccctatccac aaagatacca ctgcaaatga aaaattagaa    300

cggaatagag aatatacata ccaatggctt cacacacagg ttggggttca tgaaacgact    360

agttccagaa atatgaaatg caatcacttt ttgcctgagt tagatccaga tgtacttaat    420

ggtggaagag ttcagcttgt ggtaagaaat gtgcttaaag ttacagaaaa atgttgtaga    480

cactagtgct caaataaatg gcactttaag atatgtttat aattaaacta tgaaaatatc    540

acaactgtat ctatttggga taatatcaaa atatcatgtg ttaaaataat aacatgtttt    600

cttgacttgt aatacaattt aaaatgtgac attgcttaaa aatgttaatt ttatgtgaca    660

gatgtaaaaa tattagcatc ctacaacttt aaaataaaat tactgtggat gg            712


<210>  8099
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8099

Met Leu Lys Arg Ala Gln Lys Met Lys Ser Lys Lys Leu Lys Lys Lys 
1               5                   10                  15


Ile Asp Ser Thr Val Arg Leu Ala Leu Phe Lys Asn Asn Glu Asn Lys 
            20                  25                  30


Val Ser Leu Pro Lys Ser Pro Lys Met Val Gln Pro Arg Arg Asp Gly 
        35                  40                  45


Tyr Phe Glu Gly Ile Glu Glu Asp Pro Ile His Lys Asp Thr Thr Ala 
    50                  55                  60


Asn Glu Lys Leu Glu Arg Asn Arg Glu Tyr Thr Tyr Gln Trp Leu His 
65                  70                  75                  80


Thr Gln Val Gly Val His Glu Thr Thr Ser Ser Arg Asn Met Lys Cys 
                85                  90                  95


Asn His Phe Leu Pro Glu Leu Asp Pro Asp Val Leu Asn Gly Gly Arg 
            100                 105                 110


Val Gln Leu Val Val Arg Asn Val Leu Lys Val Thr Glu Lys Cys Cys 
        115                 120                 125


Arg His 
    130


<210>  8100
<211>  604
<212>  DNA
<213>  Homo sapiens

<400>  8100
tgtgcgtcta gccttattca aaaacaatga aaataaagtg tctcttccaa aatcaccaaa     60

gatggtacag cccagaagag atggttactt tgaaggtata gaagaagacc ctatccacaa    120

agataccact gcaaatgaaa aattagaacg gaatagagaa tatacatacc aatggcttca    180

cacacaggtt ggggttcatg aaacgactag ttccagaaat atgaaatgca atcacttttt    240

gcctgagtta gatccagatg tacttaatgg tggaagagtt cagcttgtgg caagacttgt    300

aagcagagaa gacacggatt tagacctttt ttccatgacc aatggaagtg ctttgtctgt    360

gaacagagaa aaaaaaaatc aggcacacag acactcagca ggatcttcaa gtaagttgtg    420

gtttccttca aaattaattt agaaatcaca aacgaattga tggaacctaa tgccaacaag    480

cattcttttt cagatagggg gtaggatgcc agcaacctga actgcccaaa aatgtgtatt    540

taaatttttt ctttctttaa atatcctctt ttgatataaa caaaattaaa ttatttctaa    600

aatt                                                                 604


<210>  8101
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  8101

Met Val Gln Pro Arg Arg Asp Gly Tyr Phe Glu Gly Ile Glu Glu Asp 
1               5                   10                  15


Pro Ile His Lys Asp Thr Thr Ala Asn Glu Lys Leu Glu Arg Asn Arg 
            20                  25                  30


Glu Tyr Thr Tyr Gln Trp Leu His Thr Gln Val Gly Val His Glu Thr 
        35                  40                  45


Thr Ser Ser Arg Asn Met Lys Cys Asn His Phe Leu Pro Glu Leu Asp 
    50                  55                  60


Pro Asp Val Leu Asn Gly Gly Arg Val Gln Leu Val Ala Arg Leu Val 
65                  70                  75                  80


Ser Arg Glu Asp Thr Asp Leu Asp Leu Phe Ser Met Thr Asn Gly Ser 
                85                  90                  95


Ala Leu Ser Val Asn Arg Glu Lys Lys Asn Gln Ala His Arg His Ser 
            100                 105                 110


Ala Gly Ser Ser Ser Lys Leu Trp Phe Pro Ser Lys Leu Ile 
        115                 120                 125


<210>  8102
<211>  1442
<212>  DNA
<213>  Homo sapiens

<400>  8102
gtattaaagg gaccggagcg gggcagttcc cgacgccgca gcgctcgctt tcccttccct     60

cctctctggc cctccctcct cccacccact ggctccctcc cccagcgctc tccagtttct    120

gtgccccagg agctacgcga cagtcttcca ggattatgga gtttctgagc gagaagtttg    180

ccctcaagag ccctccgagt aaaaacagtg acttttacat gggcgcagga ggtcctctgg    240

agcacgttat ggagacgctg gacaatgagt ccttttacag caaagcgtct gcaggcaaat    300

gcgtgcaggc cttcggaccc ctgccccgcg ccgagcatca cgtgcgcttg gagaggacct    360

cgccctgtca ggacagcagc gtgaactatg ggatcactaa agtagaagga cagccccttc    420

acaccgaact gaatagagct atggacaact gtaacagtct ccgaatgtct cccgtgaaag    480

ggatgcaaga gaagggagag ctggatgaac ttggggataa atgtgatagc aatgtatcca    540

gcagtaagaa acggaggcac cgaaccacct tcaccagttt gcagctagag gagctggaga    600

aagtctttca gaaaactcat tacccggatg tgtatgtcag agaacagctt gctctgagga    660

cagagctcac tgaggccagg gtccaggttt ggtttcaaaa tcgaagggcc aaatggagaa    720

aaagggaacg ttatggccaa atacaacaag cgaaaagcca ttttgctgcc acctatgata    780

tatcagtttt gccaaggact gacagctacc cacagattca gaacaatttg tgggcaggaa    840

atgcaagtgg tggttctgtg gttacttcat gcatgttacc acgtgacact tcctcctgta    900

tgacacctta ttctcactcg cctcggacag attccagtta cacggggttt tcaaaccacc    960

agaaccagtt cagccacgtg cccctcaaca attttttcac tgactctctt cttactgggg   1020

caaccaatgg acatgcattt gaaacaaagc cagagtttga aaggaggtct tccagtatcg   1080

cagttcttcg aatgaaagcc aaggagcaca ccgccaatat ttcatgggcc atgtaacata   1140

cagtactctt ttatttttct tttaatagca aagttaaaca ttcttatttc tcatatttaa   1200

aggataccac aataagctgc tgtgtgtgga attgctaaag gtcaagatat tcagtgagac   1260

cagcttaaat gaatagttgt tatttaacat taaaatctaa gaatgaacct ctgaaaagac   1320

taaataggtt taccatgtgc cagtctccac aaaccctgtt ttagtagtaa ggttttcttt   1380

ttctattgta caagtcaatg aaatatgatc acgcaactta ttaaagaata aatgtgttaa   1440

ac                                                                  1442


<210>  8103
<211>  326
<212>  PRT
<213>  Homo sapiens

<400>  8103

Met Glu Phe Leu Ser Glu Lys Phe Ala Leu Lys Ser Pro Pro Ser Lys 
1               5                   10                  15


Asn Ser Asp Phe Tyr Met Gly Ala Gly Gly Pro Leu Glu His Val Met 
            20                  25                  30


Glu Thr Leu Asp Asn Glu Ser Phe Tyr Ser Lys Ala Ser Ala Gly Lys 
        35                  40                  45


Cys Val Gln Ala Phe Gly Pro Leu Pro Arg Ala Glu His His Val Arg 
    50                  55                  60


Leu Glu Arg Thr Ser Pro Cys Gln Asp Ser Ser Val Asn Tyr Gly Ile 
65                  70                  75                  80


Thr Lys Val Glu Gly Gln Pro Leu His Thr Glu Leu Asn Arg Ala Met 
                85                  90                  95


Asp Asn Cys Asn Ser Leu Arg Met Ser Pro Val Lys Gly Met Gln Glu 
            100                 105                 110


Lys Gly Glu Leu Asp Glu Leu Gly Asp Lys Cys Asp Ser Asn Val Ser 
        115                 120                 125


Ser Ser Lys Lys Arg Arg His Arg Thr Thr Phe Thr Ser Leu Gln Leu 
    130                 135                 140


Glu Glu Leu Glu Lys Val Phe Gln Lys Thr His Tyr Pro Asp Val Tyr 
145                 150                 155                 160


Val Arg Glu Gln Leu Ala Leu Arg Thr Glu Leu Thr Glu Ala Arg Val 
                165                 170                 175


Gln Val Trp Phe Gln Asn Arg Arg Ala Lys Trp Arg Lys Arg Glu Arg 
            180                 185                 190


Tyr Gly Gln Ile Gln Gln Ala Lys Ser His Phe Ala Ala Thr Tyr Asp 
        195                 200                 205


Ile Ser Val Leu Pro Arg Thr Asp Ser Tyr Pro Gln Ile Gln Asn Asn 
    210                 215                 220


Leu Trp Ala Gly Asn Ala Ser Gly Gly Ser Val Val Thr Ser Cys Met 
225                 230                 235                 240


Leu Pro Arg Asp Thr Ser Ser Cys Met Thr Pro Tyr Ser His Ser Pro 
                245                 250                 255


Arg Thr Asp Ser Ser Tyr Thr Gly Phe Ser Asn His Gln Asn Gln Phe 
            260                 265                 270


Ser His Val Pro Leu Asn Asn Phe Phe Thr Asp Ser Leu Leu Thr Gly 
        275                 280                 285


Ala Thr Asn Gly His Ala Phe Glu Thr Lys Pro Glu Phe Glu Arg Arg 
    290                 295                 300


Ser Ser Ser Ile Ala Val Leu Arg Met Lys Ala Lys Glu His Thr Ala 
305                 310                 315                 320


Asn Ile Ser Trp Ala Met 
                325


<210>  8104
<211>  1525
<212>  DNA
<213>  Homo sapiens

<400>  8104
gtattaaagg gaccggagcg gggcagttcc cgacgccgca gcgctcgctt tcccttccct     60

cctctctggc cctccctcct cccacccact ggctccctcc cccagcgctc tccagtttct    120

gtgccccagg agctacgcga cagtcttcca ggattatgga gtttctgagc gagaagtttg    180

ccctcaagag ccctccgagt aaaaacagtg acttttacat gggcgcagga ggtcctctgg    240

agcacgttat ggagacgctg gacaatgagt ccttttacag caaagcgtct gcaggcaaat    300

gcgtgcaggc cttcggaccc ctgccccgcg ccgagcatca cgtgcgcttg gagaggacct    360

cgccctgtca ggacagcagc gtgaactatg ggatcactaa agtagaagga cagccccttc    420

acaccgaact gaatagagct atggacaact gtaacagtct ccgaatgtct cccgtgaaag    480

ggatgcaaga gaagggagag ctggatgaac ttggggataa atgtgatagc aatgtatcca    540

gcagtaagaa acggaggcac cgaaccacct tcaccagttt gcagctagag gagctggaga    600

aagtctttca gaaaactcat tacccggatg tgtatgtcag agaacagctt gctctgagga    660

cagagctcac tgaggccagg gtccaggttt ggtttcaaaa tcgaagggcc aaatggagaa    720

aaagggaacg ttatggccaa atacaacaag cgaaaagcca ttttgctgcc acctatgata    780

tatcagtttt gccaaggact gacagctacc cacagattca gaacaatttg tgggcaggaa    840

atgcaagtgg tggttctgtg gttacttcat gcatgttacc acgtgacact tcctcctgta    900

tgacacctta ttctcactcg cctcggacag attccagtta cacggggttt tcaaaccacc    960

agaaccagtt cagccacgtg cccctcaaca attttttcac tgactctctt cttactgggg   1020

caaccaatgg acatgcattt gaaacaaagc cagagtttga aaggaggtct tccagtatcg   1080

cagttcttcg aatgaaagcc aaggagcaca ccgccaatat ttcatgggcc atgtaacata   1140

cagtactctt ttatttttct tttaatagca aagttaaaca ttcttatttc tcatatttaa   1200

aggataccac aataagctgc tgtgtgtgga attgctaaag gtcaagatat tcagtgagac   1260

cagcttaaat gaatagttgt tatttaacat taaaatctaa gaatgaacct ctgaaaagac   1320

taaataggtt taccatgtgc cagtctccac aaaccctgtt ttagtagtaa ggttttcttt   1380

ttctattgta caagtcaatg aaatatgatc acgcaactta ttaaagaata aatgtgttaa   1440

acaaattctt ctgttataga ttgatttatg ttacttctgt ataacaagaa atctcatgta   1500

aaataatacc tgataaagaa ggaaa                                         1525


<210>  8105
<211>  326
<212>  PRT
<213>  Homo sapiens

<400>  8105

Met Glu Phe Leu Ser Glu Lys Phe Ala Leu Lys Ser Pro Pro Ser Lys 
1               5                   10                  15


Asn Ser Asp Phe Tyr Met Gly Ala Gly Gly Pro Leu Glu His Val Met 
            20                  25                  30


Glu Thr Leu Asp Asn Glu Ser Phe Tyr Ser Lys Ala Ser Ala Gly Lys 
        35                  40                  45


Cys Val Gln Ala Phe Gly Pro Leu Pro Arg Ala Glu His His Val Arg 
    50                  55                  60


Leu Glu Arg Thr Ser Pro Cys Gln Asp Ser Ser Val Asn Tyr Gly Ile 
65                  70                  75                  80


Thr Lys Val Glu Gly Gln Pro Leu His Thr Glu Leu Asn Arg Ala Met 
                85                  90                  95


Asp Asn Cys Asn Ser Leu Arg Met Ser Pro Val Lys Gly Met Gln Glu 
            100                 105                 110


Lys Gly Glu Leu Asp Glu Leu Gly Asp Lys Cys Asp Ser Asn Val Ser 
        115                 120                 125


Ser Ser Lys Lys Arg Arg His Arg Thr Thr Phe Thr Ser Leu Gln Leu 
    130                 135                 140


Glu Glu Leu Glu Lys Val Phe Gln Lys Thr His Tyr Pro Asp Val Tyr 
145                 150                 155                 160


Val Arg Glu Gln Leu Ala Leu Arg Thr Glu Leu Thr Glu Ala Arg Val 
                165                 170                 175


Gln Val Trp Phe Gln Asn Arg Arg Ala Lys Trp Arg Lys Arg Glu Arg 
            180                 185                 190


Tyr Gly Gln Ile Gln Gln Ala Lys Ser His Phe Ala Ala Thr Tyr Asp 
        195                 200                 205


Ile Ser Val Leu Pro Arg Thr Asp Ser Tyr Pro Gln Ile Gln Asn Asn 
    210                 215                 220


Leu Trp Ala Gly Asn Ala Ser Gly Gly Ser Val Val Thr Ser Cys Met 
225                 230                 235                 240


Leu Pro Arg Asp Thr Ser Ser Cys Met Thr Pro Tyr Ser His Ser Pro 
                245                 250                 255


Arg Thr Asp Ser Ser Tyr Thr Gly Phe Ser Asn His Gln Asn Gln Phe 
            260                 265                 270


Ser His Val Pro Leu Asn Asn Phe Phe Thr Asp Ser Leu Leu Thr Gly 
        275                 280                 285


Ala Thr Asn Gly His Ala Phe Glu Thr Lys Pro Glu Phe Glu Arg Arg 
    290                 295                 300


Ser Ser Ser Ile Ala Val Leu Arg Met Lys Ala Lys Glu His Thr Ala 
305                 310                 315                 320


Asn Ile Ser Trp Ala Met 
                325


<210>  8106
<211>  519
<212>  DNA
<213>  Homo sapiens

<400>  8106
agactgctgt gctagcaatc agcgagactc cgtgggcgta ggaccctccg agccaggcat     60

cagctatcaa aacttatggg aaatggaatt gaagacaact acttctagaa ttggtgcatg    120

gaagcttctc ataggtgatt agccacactc ttcttctgtc aacctggtgc agaaaagctt    180

gaagaccttg gaaatcacat attgatgatg gaggagatac aagaatgaag gaccctgggt    240

tcctgaatca acactctaag aagagactcc ttgaaatcaa gagcactcat tttgacattg    300

caaacggaaa aattcacttc tatcaggttt gaaccaatat atagtttagg gtttttaaaa    360

aataactgtt agcatgactt taactaatac acatgccata caggatcaga cctctgtgac    420

tttgctttta cagtctgctc tgtctggagg ggagtttcat ctttgccatc cttaatgata    480

tagcatagac gctatgtcct ccagaaactt ccttggcac                           519


<210>  8107
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  8107

Met Lys Asp Pro Gly Phe Leu Asn Gln His Ser Lys Lys Arg Leu Leu 
1               5                   10                  15


Glu Ile Lys Ser Thr His Phe Asp Ile Ala Asn Gly Lys Ile His Phe 
            20                  25                  30


Tyr Gln Val 
        35


<210>  8108
<211>  577
<212>  DNA
<213>  Homo sapiens

<400>  8108
ggaaatggaa ttgaagacaa ctacttctag aattggtgca tggaagcttc tcataggtga     60

ttagccacac tcttcttctg tcaacctggt gcagaaaagc ttgaagacct tggaaatcac    120

atattgatga tggaggagat acaagaatga aggaccctgg gttcctgaat caacactcta    180

agaagagact ccttgaaatc aagagcactc attttgacat tgcaaacgga aaaattcact    240

tctatcaggg gactgatcgg agtcaaacca tatgctgtgg cttttgctcc atggaaatct    300

caactatact gcaagaataa ttattcctac ttaatgaagt tacagaagag aatgtggtgc    360

tggacggtac tgactgcatg gggagaggcc ataccacaga aacctcaatc tgcctgagcc    420

gtgactctga gagctggagt accactggac aaggtctttg gtacttcctc ctgcattcat    480

tctccttcct gctgccctgt gaagaaggtg ccttgcttca cctttgcctt ctactatgac    540

tgtaagtttc ctgaagcctc gccagacatg ctgaact                             577


<210>  8109
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8109

Met Lys Asp Pro Gly Phe Leu Asn Gln His Ser Lys Lys Arg Leu Leu 
1               5                   10                  15


Glu Ile Lys Ser Thr His Phe Asp Ile Ala Asn Gly Lys Ile His Phe 
            20                  25                  30


Tyr Gln Gly Thr Asp Arg Ser Gln Thr Ile Cys Cys Gly Phe Cys Ser 
        35                  40                  45


Met Glu Ile Ser Thr Ile Leu Gln Glu 
    50                  55


<210>  8110
<211>  5823
<212>  DNA
<213>  Homo sapiens

<400>  8110
ccaaagtcca ggctgagtca tatggtaggt gctgtttgga atatctagcc tgcctgcctt     60

gcagattcaa atgcctcggg caggagggtg agctagctgc cgatcctgct ctgctcctgg    120

gtttgctgtg tggcccttgg tagaacgtca tgacatgaat accttaagcc tgcccctgaa    180

catacgccga ggggggtcag acaccaacct caactttgat gtcccggatg gcatcctgga    240

cttccacaag gtcaaactca ctgcagacag cctgaagcaa aaaattctaa aggtaacaga    300

gcagataaaa attgagcaaa catcgcgcga tgggaatgtt gcggagtatc tgaaactagt    360

gaacaacgca gacaagcagc aggcgggacg tatcaagcaa gtctttgaga agaagaatca    420

gaaatcagct cactccatcg cccagctgca gaagaagtta gagcagtatc atcgaaagct    480

cagagagatc gagcagaatg gagcctctag gagctcaaag gacatttcca aagaccacct    540

gaaggatata catcgctctt tgaaagatgc ccacgtgaaa tctcgaactg ccccccattg    600

catggagagc agcaaatcgg gcatgccagg ggtctcactt actccacctg tgttcgtttt    660

caataagtcc agagagtttg ccaacctgat ccggaataag tttggcagcg ccgacaacat    720

tgctcacttg aaaaattcct tagaggagtt taggccagag gcgagtgcca gggcctacgg    780

gggcagcgct accatcgtga acaaacccaa gtatggcagt gatgatgaat gttcgagtgg    840

cacgtcaggc tcggccgaca gtaacggaaa ccagtcgttt ggggctggtg gagccagcac    900

actggacagc cagggcaagc tcgccgtgat cctggaggaa ctgagggaga tcaaggatac    960

ccaagctcag ctggctgagg acatcgaggc actgaaggtg cagtttaaga gagaatatgg   1020

ttttatttct cagaccctgc aagaggaaag atacaggtat gagcgactgg aggaccagct   1080

gcatgacctg acggacctgc atcagcatga gacagccaac ctgaagcagg agctggccag   1140

cattgaggag aaggtggcct accaggccta cgagcgctcg cgggacatcc aggaagcctt   1200

ggaatcctgc cagactcgca tttctaagct ggagctccac cagcaagagc agcaagctct   1260

gcagacagac accgtgaatg ctaaagttct cctggggagg tgcatcaacg tgatcctggc   1320

cttcatgact gtcatcttag tgtgtgtgtc caccatcgcg aagttcgtct cacccatgat   1380

gaagagtcgc tgccacattc ttggcacctt ctttgccgtg actcttcttg ctatattttg   1440

taaaaactgg gaccatatcc tgtgtgccat agaaaggatg ataataccaa gatgaagcca   1500

ctggttcctg ccttcaagtt ctttcaagtt tttattttaa agaaaactct gtgcatacta   1560

ccaaatttta cagtgaatga ttgtgcggac tcgtgtgtaa gaaaaactag gactgtgtgg   1620

tgtaaataac tacaattctc ttaactccgt agcagttgcc aactcagtcc ttgtacttcg   1680

ttaacacgaa tctgtttcag agctctccta ccttgctcac tgccttaatc agaccgattt   1740

cctgcccacc tgaccagccc agcgtggtaa acctctgtat attgagacct tggcataatt   1800

ggtgatcctg aagaaagagg tctctctcct aagtctctgt cagaattgag cttcacaatt   1860

gctaatggtt gttttctgtg agtcctataa aaagcaagga tatgcatgat tcagggaatg   1920

aagaatcaca ggcttgggca gtgttaaaca ctgtggccta tggtccccgt gtgatccacc   1980

ctgcttctct ccaggggacc ataggtcccg tcatgtactc agtgtccaca gcagtcagtc   2040

gtgtatgacc ctgtaacgtg gaaatcttat cacacacctg ttatccaaca agtctacctg   2100

aggggttttg ttacacttta aatgggaagg catagggatt tatgaatggg gctttcacct   2160

tctcataccc aggcaaccaa cacctgattt tgtctcaact ggctagcaaa tgcccagcct   2220

tcagagtgtg caggaatgtt ttcaaatccc tcatcagact gtgactttaa cattaatttg   2280

gaatcctgtg agcactactc tgaaggtttg tgttttggca aatctttttt cttttttgag   2340

acagggctct gctaaatatt gctcaggctg gttgcaaact ccttgcttca agggatcctc   2400

ccacctcagc ctcccaagca gccgggactg caggcacaag ccaccatgcc tggctgtttt   2460

ttggcaaatc ttgattgtga taagcccccc tggaggatat gattcacttt atgtgattca   2520

tcttattcac aggtctgtga gggactgcaa agcttactca ggaaatgaaa acaaatgatg   2580

gtcatgttgc agttttttcc ttgaaggaca accgaaccat agcctctaaa gttcaagtgc   2640

actgaggtgt cggaacgctg aaagcatgag gaaacgagga cgtagggtgt gactgaatgg   2700

tggctagatt agtgggagca gttcacctgg atgaagattg agagcatcgt ctttgagaag   2760

tgaaagacta gcaagaataa aataaattaa gtccagtgtt tgagccaagg ttgccacctg   2820

tctcttaaca tctcactgaa cataagtcct gaggtattag gacgaccata ctgcctctga   2880

gctgaaaaca ttcaaaagtt cacatccctg tttgggggat accattcacc gccttcagcc   2940

cagatgatac tttcctttaa atctgtgtct ctgtgtgtat aacaaagagg aagatggaaa   3000

caatgttcat ggaaactgct gttgagcccc ttgtcccacc actcccgcca tctgctgcag   3060

gcaggaaggc atgtgagtgt acgttttctt ccaggagaca tcaggtcccc ctggattcaa   3120

attaagtgca atattttgca aacagctctt cttagggaaa tctcctgaag gaaaaaaatg   3180

tgacagaatg ttccatagtc tgagagaatg gaatcgttga gcatttagta caagtccagt   3240

gtgtgtgagc gggacttagg cagctcaagc ttgctttttt ttttaagcgt acaattgagt   3300

ggttttagta aattcacaaa cttgttcaac catcaccact atctaattcc agactcacgc   3360

ttttttaaac aataaatgtc atttcatgaa atctttggtg ataaagtatt ttggattcag   3420

agaagagctc ccttaccagt cccaccctga tctcatggct gtctctcctt tcattgtcag   3480

actccccctg gtctaccgcg ttgatgtgta tacactgatc tttcaagtct gggagacaga   3540

taaggaggcc aggtgcaagg cagggaggca gagagaatgt tgtgcttcct ttagcttttg   3600

tatttcgatg gccagcatta ccctttacct gtgggcatca gactcagcgt gggctgagtg   3660

ctgagtgtaa cttacactcc taaatcaagc tggggcctgg gtgggcccct cttggtatct   3720

gtgaatcttt ccaagcacca cttcggacac accagggatt gagtgctgct gttagtttag   3780

agaaggagag atgtctaacc cttgaggtga agggctctgg gagggtccaa gaagacgtag   3840

gcttcatttt cacaccagcc cacaccattc cagtgctcag cctagcaaat gtgctttaat   3900

gcacacttct cagacctgtg atccgtgtat cttctcccca gtgacagaag tagagaagag   3960

aatggaaagc agcacactcc gtcccctcta gtctggagct gttaacagaa tctgctagaa   4020

actagcttta ttctaacata ccgtaggatc taaatcctcc tacctggatc atgaattcct   4080

ttgaaataat tcatattttc attgactctc actaaatgtc aaataacctt gttttcactt   4140

ggataggctc aacctacctg gcatatttat tttgcagtct tgttgaaagt tcatgaaact   4200

ttgtactttt taataagatg atacactcga aggaaacttt taatctctgc agtttattct   4260

ctcttaagga ataaacactc ccactgtttg ttctcttcaa tgtgtaagga gattaaatga   4320

cattttagaa atattacaat taaaaatagt gatgtagctg taacatatgc tggaattgga   4380

tatttaattt atgtttgtgt caactataat cctttcccca cccctttcat ttatggtaaa   4440

catcttgggc aaacccaaag atggaaagtg cttgttgggt gggtaagcac cacctggtct   4500

ctcagcaaac actcctgagt ggttgaagat gctggacatt ggattctagc actgggttta   4560

tctggtgaca tagtctcctg tgggtcttga gttggttatt tcaagctcaa actctgaata   4620

tgattaaacc agaacacccc acccccaact gccaaaaaaa aaaaaaaaaa atggaaatcc   4680

ataatgaaac agcaaaaaag tactccgttg ctgggtttgg acaatgaaca tgggattagt   4740

cccaagtttg tagcttggaa cggtagcatt tttgcctgcg tgatccttgt cagctattca   4800

cagaaggaaa tcttccgaaa ctccgtcttt catttcagcc ggtgaggctg ttatccttct   4860

ctgtcaatta gcattcatgt ggttttcgct ctttccagct ctgtcactct tgttttcatt   4920

taaatattgc cccactctgt gtttattgcc ttgccatttc tctagcatat caggtttaat   4980

tatgggctca gtaataatga ggaactagct tccctcaggc aactaattac ttttgtcttt   5040

tttggtcgga ttgtaccaaa ttattttgca ttgaatggga atgtttttgc agtgaatcca   5100

gatatagttg tattggtttg gaaaaacatt taaatatatt tattcatatg aacatgtgtg   5160

attaaacaac ctattttaca tatttctgta attctgagga gtgggctggg ggtaggaaga   5220

aatggcacca cttaaaattc agggcttata tgaagaggtg ttttaaggtt agcacatgca   5280

caaaggaacg agttggttta aaaagataaa tcactgcaaa gaatgaaatt ggcttattca   5340

catcaaaact agataagatg ctaaaaaaaa aagatatgaa acagaactaa cctatagttt   5400

cctgaaatca gtacagttta atttataaga agctagaaag taatgcacct tgattgtttt   5460

aggaatgatt tatgtgttgc aattttaatt tatttaaagc atgtctactg tgtttgtcct   5520

aagagaaata tttcaacaaa acgtgctctg tgtttaagat atgtttaggc agtagttagc   5580

aactctgaaa gtagaaactg gaaatgttta ttgtgaggct tgttgcagaa tttccatttt   5640

gtgagttact acttagtttc atgtcagcct aaaattgtaa attccctgta gatcttcacc   5700

ccattgtggt gtcatcaatg aatccaaagc aggtgccatt atttttttaa ataaacactt   5760

gatgttagct ttggtgttaa ataaagaggt agatttctta aattttcaca tttgttggag   5820

ccc                                                                 5823


<210>  8111
<211>  446
<212>  PRT
<213>  Homo sapiens

<400>  8111

Met Asn Thr Leu Ser Leu Pro Leu Asn Ile Arg Arg Gly Gly Ser Asp 
1               5                   10                  15


Thr Asn Leu Asn Phe Asp Val Pro Asp Gly Ile Leu Asp Phe His Lys 
            20                  25                  30


Val Lys Leu Thr Ala Asp Ser Leu Lys Gln Lys Ile Leu Lys Val Thr 
        35                  40                  45


Glu Gln Ile Lys Ile Glu Gln Thr Ser Arg Asp Gly Asn Val Ala Glu 
    50                  55                  60


Tyr Leu Lys Leu Val Asn Asn Ala Asp Lys Gln Gln Ala Gly Arg Ile 
65                  70                  75                  80


Lys Gln Val Phe Glu Lys Lys Asn Gln Lys Ser Ala His Ser Ile Ala 
                85                  90                  95


Gln Leu Gln Lys Lys Leu Glu Gln Tyr His Arg Lys Leu Arg Glu Ile 
            100                 105                 110


Glu Gln Asn Gly Ala Ser Arg Ser Ser Lys Asp Ile Ser Lys Asp His 
        115                 120                 125


Leu Lys Asp Ile His Arg Ser Leu Lys Asp Ala His Val Lys Ser Arg 
    130                 135                 140


Thr Ala Pro His Cys Met Glu Ser Ser Lys Ser Gly Met Pro Gly Val 
145                 150                 155                 160


Ser Leu Thr Pro Pro Val Phe Val Phe Asn Lys Ser Arg Glu Phe Ala 
                165                 170                 175


Asn Leu Ile Arg Asn Lys Phe Gly Ser Ala Asp Asn Ile Ala His Leu 
            180                 185                 190


Lys Asn Ser Leu Glu Glu Phe Arg Pro Glu Ala Ser Ala Arg Ala Tyr 
        195                 200                 205


Gly Gly Ser Ala Thr Ile Val Asn Lys Pro Lys Tyr Gly Ser Asp Asp 
    210                 215                 220


Glu Cys Ser Ser Gly Thr Ser Gly Ser Ala Asp Ser Asn Gly Asn Gln 
225                 230                 235                 240


Ser Phe Gly Ala Gly Gly Ala Ser Thr Leu Asp Ser Gln Gly Lys Leu 
                245                 250                 255


Ala Val Ile Leu Glu Glu Leu Arg Glu Ile Lys Asp Thr Gln Ala Gln 
            260                 265                 270


Leu Ala Glu Asp Ile Glu Ala Leu Lys Val Gln Phe Lys Arg Glu Tyr 
        275                 280                 285


Gly Phe Ile Ser Gln Thr Leu Gln Glu Glu Arg Tyr Arg Tyr Glu Arg 
    290                 295                 300


Leu Glu Asp Gln Leu His Asp Leu Thr Asp Leu His Gln His Glu Thr 
305                 310                 315                 320


Ala Asn Leu Lys Gln Glu Leu Ala Ser Ile Glu Glu Lys Val Ala Tyr 
                325                 330                 335


Gln Ala Tyr Glu Arg Ser Arg Asp Ile Gln Glu Ala Leu Glu Ser Cys 
            340                 345                 350


Gln Thr Arg Ile Ser Lys Leu Glu Leu His Gln Gln Glu Gln Gln Ala 
        355                 360                 365


Leu Gln Thr Asp Thr Val Asn Ala Lys Val Leu Leu Gly Arg Cys Ile 
    370                 375                 380


Asn Val Ile Leu Ala Phe Met Thr Val Ile Leu Val Cys Val Ser Thr 
385                 390                 395                 400


Ile Ala Lys Phe Val Ser Pro Met Met Lys Ser Arg Cys His Ile Leu 
                405                 410                 415


Gly Thr Phe Phe Ala Val Thr Leu Leu Ala Ile Phe Cys Lys Asn Trp 
            420                 425                 430


Asp His Ile Leu Cys Ala Ile Glu Arg Met Ile Ile Pro Arg 
        435                 440                 445


<210>  8112
<211>  3452
<212>  DNA
<213>  Homo sapiens

<400>  8112
tattgggtac agtgcagggc gtggagtttc tctgagacaa acacaggaat accccgagat     60

aatgtgagca gtatctccaa agtccaggct gagtcatatg gtaggtgctg tttggaatat    120

ctagcctgcc tgccttgcag attcaaatgc ctcgggcagg agggtgagct agctgccgat    180

cctgcttcag gaaatgaaaa caaatgatgg tcatgttgca gttttttcct tgaaggacaa    240

ccgaaccata gcctctaaag ttcaagtgca ctgaggtgtc ggaacgctga aagcatgagg    300

aaacgaggac gtagggtgtg actgaatggt ggctagatta gtgggagcag ttcacctgga    360

tgaagattga gagcatcgtc tttgagaagt gaaagactag caagaataaa ataaattaag    420

tccagtgttt gagccaaggt tgccacctgt ctcttaacat ctcactgaac ataagtcctg    480

aggtattagg acgaccatac tgcctctgag ctgaaaacat tcaaaagttc acatccctgt    540

ttgggggata ccattcaccg ccttcagccc agatgatact ttcctttaaa tctgtgtctc    600

tgtgtgtata acaaagagga agatggaaac aatgttcatg gaaactgctg ttgagcccct    660

tgtcccacca ctcccgccat ctgctgcagg caggaaggca tgtgagtgta cgttttcttc    720

caggagacat caggtccccc tggattcaaa ttaagtgcaa tattttgcaa acagctcttc    780

ttagggaaat ctcctgaagg aaaaaaatgt gacagaatgt tccatagtct gagagaatgg    840

aatcgttgag catttagtac aagtccagtg tgtgtgagcg ggacttaggc agctcaagct    900

tgcttttttt tttaagcgta caattgagtg gttttagtaa attcacaaac ttgttcaacc    960

atcaccacta tctaattcca gactcacgct tttttaaaca ataaatgtca tttcatgaaa   1020

tctttggtga taaagtattt tggattcaga gaagagctcc cttaccagtc ccaccctgat   1080

ctcatggctg tctctccttt cattgtcaga ctccccctgg tctaccgcgt tgatgtgtat   1140

acactgatct ttcaagtctg ggagacagat aaggaggcca ggtgcaaggc agggaggcag   1200

agagaatgtt gtgcttcctt tagcttttgt atttcgatgg ccagcattac cctttacctg   1260

tgggcatcag actcagcgtg ggctgagtgc tgagtgtaac ttacactcct aaatcaagct   1320

ggggcctggg tgggcccctc ttggtatctg tgaatctttc caagcaccac ttcggacaca   1380

ccagggattg agtgctgctg ttagtttaga gaaggagaga tgtctaaccc ttgaggtgaa   1440

gggctctggg agggtccaag aagacgtagg cttcattttc acaccagccc acaccattcc   1500

agtgctcagc ctagcaaatg tgctttaatg cacacttctc agacctgtga tccgtgtatc   1560

ttctccccag tgacagaagt agagaagaga atggaaagca gcacactccg tcccctctag   1620

tctggagctg ttaacagaat ctgctagaaa ctagctttat tctaacatac cgtaggatct   1680

aaatcctcct acctggatca tgaattcctt tgaaataatt catattttca ttgactctca   1740

ctaaatgtca aataaccttg ttttcacttg gataggctca acctacctgg catatttatt   1800

ttgcagtctt gttgaaagtt catgaaactt tgtacttttt aataagatga tacactcgaa   1860

ggaaactttt aatctctgca gtttattctc tcttaaggaa taaacactcc cactgtttgt   1920

tctcttcaat gtgtaaggag attaaatgac attttagaaa tattacaatt aaaaatagtg   1980

atgtagctgt aacatatgct ggaattggat atttaattta tgtttgtgtc aactataatc   2040

ctttccccac ccctttcatt tatggtaaac atcttgggca aacccaaaga tggaaagtgc   2100

ttgttgggtg ggtaagcacc acctggtctc tcagcaaaca ctcctgagtg gttgaagatg   2160

ctggacattg gattctagca ctgggtttat ctggtgacat agtctcctgt gggtcttgag   2220

ttggttattt caagctcaaa ctctgaatat gattaaacca gaacacccca cccccaactg   2280

ccaaaaaaaa aaaaaaaaaa tggaaatcca taatgaaaca gcaaaaaagt actccgttgc   2340

tgggtttgga caatgaacat gggattagtc ccaagtttgt agcttggaac ggtagcattt   2400

ttgcctgcgt gatccttgtc agctattcac agaaggaaat cttccgaaac tccgtctttc   2460

atttcagccg gtgaggctgt tatccttctc tgtcaattag cattcatgtg gttttcgctc   2520

tttccagctc tgtcactctt gttttcattt aaatattgcc ccactctgtg tttattgcct   2580

tgccatttct ctagcatatc aggtttaatt atgggctcag taataatgag gaactagctt   2640

ccctcaggca actaattact tttgtctttt ttggtcggat tgtaccaaat tattttgcat   2700

tgaatgggaa tgtttttgca gtgaatccag atatagttgt attggtttgg aaaaacattt   2760

aaatatattt attcatatga acatgtgtga ttaaacaacc tattttacat atttctgtaa   2820

ttctgaggag tgggctgggg gtaggaagaa atggcaccac ttaaaattca gggcttatat   2880

gaagaggtgt tttaaggtta gcacatgcac aaaggaacga gttggtttaa aaagataaat   2940

cactgcaaag aatgaaattg gcttattcac atcaaaacta gataagatgc taaaaaaaaa   3000

agatatgaaa cagaactaac ctatagtttc ctgaaatcag tacagtttaa tttataagaa   3060

gctagaaagt aatgcacctt gattgtttta ggaatgattt atgtgttgca attttaattt   3120

atttaaagca tgtctactgt gtttgtccta agagaaatat ttcaacaaaa cgtgctctgt   3180

gtttaagata tgtttaggca gtagttagca actctgaaag tagaaactgg aaatgtttat   3240

tgtgaggctt gttgcagaat ttccattttg tgagttacta cttagtttca tgtcagccta   3300

aaattgtaaa ttccctgtag atcttcaccc cattgtggtg tcatcaatga atccaaagca   3360

ggtgccatta tttttttaaa taaacacttg atgttagctt tggtgttaaa taaagaggta   3420

gatttcttaa attttcacat ttgttggagc cc                                 3452


<210>  8113
<211>  92
<212>  PRT
<213>  Homo sapiens

<400>  8113

Met Lys Ser Leu Val Ile Lys Tyr Phe Gly Phe Arg Glu Glu Leu Pro 
1               5                   10                  15


Tyr Gln Ser His Pro Asp Leu Met Ala Val Ser Pro Phe Ile Val Arg 
            20                  25                  30


Leu Pro Leu Val Tyr Arg Val Asp Val Tyr Thr Leu Ile Phe Gln Val 
        35                  40                  45


Trp Glu Thr Asp Lys Glu Ala Arg Cys Lys Ala Gly Arg Gln Arg Glu 
    50                  55                  60


Cys Cys Ala Ser Phe Ser Phe Cys Ile Ser Met Ala Ser Ile Thr Leu 
65                  70                  75                  80


Tyr Leu Trp Ala Ser Asp Ser Ala Trp Ala Glu Cys 
                85                  90


<210>  8114
<211>  5889
<212>  DNA
<213>  Homo sapiens

<400>  8114
agaggcaaca gctgcagcag ccgcgccgcc ccctcgcccg cggctcccag ggtgatcccg     60

agcacagccg gtggctcgcg gcgcggcagc cccagaagac gggaaagttc gcggccggag    120

cgcggagatg ccgggcagcg acacggcgct caccgtggac cggacctact cgtaccccgg    180

ccggcaccac cgctgcaaga gccgggtaga acgtcatgac atgaatacct taagcctgcc    240

cctgaacata cgccgagggg ggtcagacac caacctcaac tttgatgtcc cggatggcat    300

cctggacttc cacaaggtca aactcactgc agacagcctg aagcaaaaaa ttctaaaggt    360

aacagagcag ataaaaattg agcaaacatc gcgcgatggg aatgttgcgg agtatctgaa    420

actagtgaac aacgcagaca agcagcaggc gggacgtatc aagcaagtct ttgagaagaa    480

gaatcagaaa tcagctcact ccatcgccca gctgcagaag aagttagagc agtatcatcg    540

aaagctcaga gagatcgagc agaatggagc ctctaggagc tcaaaggaca tttccaaaga    600

ccacctgaag gatatacatc gctctttgaa agatgcccac gtgaaatctc gaactgcccc    660

ccattgcatg gagagcagca aatcgggcat gccaggggtc tcacttactc cacctgtgtt    720

cgttttcaat aagtccagag agtttgccaa cctgatccgg aataagtttg gcagcgccga    780

caacattgct cacttgaaaa attccttaga ggagtttagg ccagaggcga gtgccagggc    840

ctacgggggc agcgctacca tcgtgaacaa acccaagtat ggcagtgatg atgaatgttc    900

gagtggcacg tcaggctcgg ccgacagtaa cggaaaccag tcgtttgggg ctggtggagc    960

cagcacactg gacagccagg gcaagctcgc cgtgatcctg gaggaactga gggagatcaa   1020

ggatacccaa gctcagctgg ctgaggacat cgaggcactg aaggtgcagt ttaagagaga   1080

atatggtttt atttctcaga ccctgcaaga ggaaagatac aggtatgagc gactggagga   1140

ccagctgcat gacctgacgg acctgcatca gcatgagaca gccaacctga agcaggagct   1200

ggccagcatt gaggagaagg tggcctacca ggcctacgag cgctcgcggg acatccagga   1260

agccttggaa tcctgccaga ctcgcatttc taagctggag ctccaccagc aagagcagca   1320

agctctgcag acagacaccg tgaatgctaa agttctcctg gggaggtgca tcaacgtgat   1380

cctggccttc atgactgtca tcttagtgtg tgtgtccacc atcgcgaagt tcgtctcacc   1440

catgatgaag agtcgctgcc acattcttgg caccttcttt gccgtgactc ttcttgctat   1500

attttgtaaa aactgggacc atatcctgtg tgccatagaa aggatgataa taccaagatg   1560

aagccactgg ttcctgcctt caagttcttt caagttttta ttttaaagaa aactctgtgc   1620

atactaccaa attttacagt gaatgattgt gcggactcgt gtgtaagaaa aactaggact   1680

gtgtggtgta aataactaca attctcttaa ctccgtagca gttgccaact cagtccttgt   1740

acttcgttaa cacgaatctg tttcagagct ctcctacctt gctcactgcc ttaatcagac   1800

cgatttcctg cccacctgac cagcccagcg tggtaaacct ctgtatattg agaccttggc   1860

ataattggtg atcctgaaga aagaggtctc tctcctaagt ctctgtcaga attgagcttc   1920

acaattgcta atggttgttt tctgtgagtc ctataaaaag caaggatatg catgattcag   1980

ggaatgaaga atcacaggct tgggcagtgt taaacactgt ggcctatggt ccccgtgtga   2040

tccaccctgc ttctctccag gggaccatag gtcccgtcat gtactcagtg tccacagcag   2100

tcagtcgtgt atgaccctgt aacgtggaaa tcttatcaca cacctgttat ccaacaagtc   2160

tacctgaggg gttttgttac actttaaatg ggaaggcata gggatttatg aatggggctt   2220

tcaccttctc atacccaggc aaccaacacc tgattttgtc tcaactggct agcaaatgcc   2280

cagccttcag agtgtgcagg aatgttttca aatccctcat cagactgtga ctttaacatt   2340

aatttggaat cctgtgagca ctactctgaa ggtttgtgtt ttggcaaatc ttttttcttt   2400

tttgagacag ggctctgcta aatattgctc aggctggttg caaactcctt gcttcaaggg   2460

atcctcccac ctcagcctcc caagcagccg ggactgcagg cacaagccac catgcctggc   2520

tgttttttgg caaatcttga ttgtgataag cccccctgga ggatatgatt cactttatgt   2580

gattcatctt attcacaggt ctgtgaggga ctgcaaagct tactcaggaa atgaaaacaa   2640

atgatggtca tgttgcagtt ttttccttga aggacaaccg aaccatagcc tctaaagttc   2700

aagtgcactg aggtgtcgga acgctgaaag catgaggaaa cgaggacgta gggtgtgact   2760

gaatggtggc tagattagtg ggagcagttc acctggatga agattgagag catcgtcttt   2820

gagaagtgaa agactagcaa gaataaaata aattaagtcc agtgtttgag ccaaggttgc   2880

cacctgtctc ttaacatctc actgaacata agtcctgagg tattaggacg accatactgc   2940

ctctgagctg aaaacattca aaagttcaca tccctgtttg ggggatacca ttcaccgcct   3000

tcagcccaga tgatactttc ctttaaatct gtgtctctgt gtgtataaca aagaggaaga   3060

tggaaacaat gttcatggaa actgctgttg agccccttgt cccaccactc ccgccatctg   3120

ctgcaggcag gaaggcatgt gagtgtacgt tttcttccag gagacatcag gtccccctgg   3180

attcaaatta agtgcaatat tttgcaaaca gctcttctta gggaaatctc ctgaaggaaa   3240

aaaatgtgac agaatgttcc atagtctgag agaatggaat cgttgagcat ttagtacaag   3300

tccagtgtgt gtgagcggga cttaggcagc tcaagcttgc tttttttttt aagcgtacaa   3360

ttgagtggtt ttagtaaatt cacaaacttg ttcaaccatc accactatct aattccagac   3420

tcacgctttt ttaaacaata aatgtcattt catgaaatct ttggtgataa agtattttgg   3480

attcagagaa gagctccctt accagtccca ccctgatctc atggctgtct ctcctttcat   3540

tgtcagactc cccctggtct accgcgttga tgtgtataca ctgatctttc aagtctggga   3600

gacagataag gaggccaggt gcaaggcagg gaggcagaga gaatgttgtg cttcctttag   3660

cttttgtatt tcgatggcca gcattaccct ttacctgtgg gcatcagact cagcgtgggc   3720

tgagtgctga gtgtaactta cactcctaaa tcaagctggg gcctgggtgg gcccctcttg   3780

gtatctgtga atctttccaa gcaccacttc ggacacacca gggattgagt gctgctgtta   3840

gtttagagaa ggagagatgt ctaacccttg aggtgaaggg ctctgggagg gtccaagaag   3900

acgtaggctt cattttcaca ccagcccaca ccattccagt gctcagccta gcaaatgtgc   3960

tttaatgcac acttctcaga cctgtgatcc gtgtatcttc tccccagtga cagaagtaga   4020

gaagagaatg gaaagcagca cactccgtcc cctctagtct ggagctgtta acagaatctg   4080

ctagaaacta gctttattct aacataccgt aggatctaaa tcctcctacc tggatcatga   4140

attcctttga aataattcat attttcattg actctcacta aatgtcaaat aaccttgttt   4200

tcacttggat aggctcaacc tacctggcat atttattttg cagtcttgtt gaaagttcat   4260

gaaactttgt actttttaat aagatgatac actcgaagga aacttttaat ctctgcagtt   4320

tattctctct taaggaataa acactcccac tgtttgttct cttcaatgtg taaggagatt   4380

aaatgacatt ttagaaatat tacaattaaa aatagtgatg tagctgtaac atatgctgga   4440

attggatatt taatttatgt ttgtgtcaac tataatcctt tccccacccc tttcatttat   4500

ggtaaacatc ttgggcaaac ccaaagatgg aaagtgcttg ttgggtgggt aagcaccacc   4560

tggtctctca gcaaacactc ctgagtggtt gaagatgctg gacattggat tctagcactg   4620

ggtttatctg gtgacatagt ctcctgtggg tcttgagttg gttatttcaa gctcaaactc   4680

tgaatatgat taaaccagaa caccccaccc ccaactgcca aaaaaaaaaa aaaaaaatgg   4740

aaatccataa tgaaacagca aaaaagtact ccgttgctgg gtttggacaa tgaacatggg   4800

attagtccca agtttgtagc ttggaacggt agcatttttg cctgcgtgat ccttgtcagc   4860

tattcacaga aggaaatctt ccgaaactcc gtctttcatt tcagccggtg aggctgttat   4920

ccttctctgt caattagcat tcatgtggtt ttcgctcttt ccagctctgt cactcttgtt   4980

ttcatttaaa tattgcccca ctctgtgttt attgccttgc catttctcta gcatatcagg   5040

tttaattatg ggctcagtaa taatgaggaa ctagcttccc tcaggcaact aattactttt   5100

gtcttttttg gtcggattgt accaaattat tttgcattga atgggaatgt ttttgcagtg   5160

aatccagata tagttgtatt ggtttggaaa aacatttaaa tatatttatt catatgaaca   5220

tgtgtgatta aacaacctat tttacatatt tctgtaattc tgaggagtgg gctgggggta   5280

ggaagaaatg gcaccactta aaattcaggg cttatatgaa gaggtgtttt aaggttagca   5340

catgcacaaa ggaacgagtt ggtttaaaaa gataaatcac tgcaaagaat gaaattggct   5400

tattcacatc aaaactagat aagatgctaa aaaaaaaaga tatgaaacag aactaaccta   5460

tagtttcctg aaatcagtac agtttaattt ataagaagct agaaagtaat gcaccttgat   5520

tgttttagga atgatttatg tgttgcaatt ttaatttatt taaagcatgt ctactgtgtt   5580

tgtcctaaga gaaatatttc aacaaaacgt gctctgtgtt taagatatgt ttaggcagta   5640

gttagcaact ctgaaagtag aaactggaaa tgtttattgt gaggcttgtt gcagaatttc   5700

cattttgtga gttactactt agtttcatgt cagcctaaaa ttgtaaattc cctgtagatc   5760

ttcaccccat tgtggtgtca tcaatgaatc caaagcaggt gccattattt ttttaaataa   5820

acacttgatg ttagctttgg tgttaaataa agaggtagat ttcttaaatt ttcacatttg   5880

ttggagccc                                                           5889


<210>  8115
<211>  477
<212>  PRT
<213>  Homo sapiens

<400>  8115

Met Pro Gly Ser Asp Thr Ala Leu Thr Val Asp Arg Thr Tyr Ser Tyr 
1               5                   10                  15


Pro Gly Arg His His Arg Cys Lys Ser Arg Val Glu Arg His Asp Met 
            20                  25                  30


Asn Thr Leu Ser Leu Pro Leu Asn Ile Arg Arg Gly Gly Ser Asp Thr 
        35                  40                  45


Asn Leu Asn Phe Asp Val Pro Asp Gly Ile Leu Asp Phe His Lys Val 
    50                  55                  60


Lys Leu Thr Ala Asp Ser Leu Lys Gln Lys Ile Leu Lys Val Thr Glu 
65                  70                  75                  80


Gln Ile Lys Ile Glu Gln Thr Ser Arg Asp Gly Asn Val Ala Glu Tyr 
                85                  90                  95


Leu Lys Leu Val Asn Asn Ala Asp Lys Gln Gln Ala Gly Arg Ile Lys 
            100                 105                 110


Gln Val Phe Glu Lys Lys Asn Gln Lys Ser Ala His Ser Ile Ala Gln 
        115                 120                 125


Leu Gln Lys Lys Leu Glu Gln Tyr His Arg Lys Leu Arg Glu Ile Glu 
    130                 135                 140


Gln Asn Gly Ala Ser Arg Ser Ser Lys Asp Ile Ser Lys Asp His Leu 
145                 150                 155                 160


Lys Asp Ile His Arg Ser Leu Lys Asp Ala His Val Lys Ser Arg Thr 
                165                 170                 175


Ala Pro His Cys Met Glu Ser Ser Lys Ser Gly Met Pro Gly Val Ser 
            180                 185                 190


Leu Thr Pro Pro Val Phe Val Phe Asn Lys Ser Arg Glu Phe Ala Asn 
        195                 200                 205


Leu Ile Arg Asn Lys Phe Gly Ser Ala Asp Asn Ile Ala His Leu Lys 
    210                 215                 220


Asn Ser Leu Glu Glu Phe Arg Pro Glu Ala Ser Ala Arg Ala Tyr Gly 
225                 230                 235                 240


Gly Ser Ala Thr Ile Val Asn Lys Pro Lys Tyr Gly Ser Asp Asp Glu 
                245                 250                 255


Cys Ser Ser Gly Thr Ser Gly Ser Ala Asp Ser Asn Gly Asn Gln Ser 
            260                 265                 270


Phe Gly Ala Gly Gly Ala Ser Thr Leu Asp Ser Gln Gly Lys Leu Ala 
        275                 280                 285


Val Ile Leu Glu Glu Leu Arg Glu Ile Lys Asp Thr Gln Ala Gln Leu 
    290                 295                 300


Ala Glu Asp Ile Glu Ala Leu Lys Val Gln Phe Lys Arg Glu Tyr Gly 
305                 310                 315                 320


Phe Ile Ser Gln Thr Leu Gln Glu Glu Arg Tyr Arg Tyr Glu Arg Leu 
                325                 330                 335


Glu Asp Gln Leu His Asp Leu Thr Asp Leu His Gln His Glu Thr Ala 
            340                 345                 350


Asn Leu Lys Gln Glu Leu Ala Ser Ile Glu Glu Lys Val Ala Tyr Gln 
        355                 360                 365


Ala Tyr Glu Arg Ser Arg Asp Ile Gln Glu Ala Leu Glu Ser Cys Gln 
    370                 375                 380


Thr Arg Ile Ser Lys Leu Glu Leu His Gln Gln Glu Gln Gln Ala Leu 
385                 390                 395                 400


Gln Thr Asp Thr Val Asn Ala Lys Val Leu Leu Gly Arg Cys Ile Asn 
                405                 410                 415


Val Ile Leu Ala Phe Met Thr Val Ile Leu Val Cys Val Ser Thr Ile 
            420                 425                 430


Ala Lys Phe Val Ser Pro Met Met Lys Ser Arg Cys His Ile Leu Gly 
        435                 440                 445


Thr Phe Phe Ala Val Thr Leu Leu Ala Ile Phe Cys Lys Asn Trp Asp 
    450                 455                 460


His Ile Leu Cys Ala Ile Glu Arg Met Ile Ile Pro Arg 
465                 470                 475


<210>  8116
<211>  1017
<212>  DNA
<213>  Homo sapiens

<400>  8116
tattgggtac agtgcagggc gtggagtttc tctgagacaa acacaggaat accccgagat     60

aatgtgagca gtatctccaa agtccaggct gagtcatatg gtaggtgctg tttggaatat    120

ctagcctgcc tgccttgcag attcaaatgc ctcgggcagg agggtgagct agctgccgat    180

cctgcttcag gaaatgaaaa caaatgatgg tcatgttgca gttttttcct tgaaggacaa    240

ccgaaccata gcctctaaag ttcaagtgca ctgaggtgtc ggaacgctga aagcatgagg    300

aaacgaggac gtagggtgtg actgaatggt ggctagatta gtgggagcag ttcacctgga    360

tgaagattga gagcatcgtc tttgagaagt gaaagactag caagaataaa ataaattaag    420

tccagtgttt gagccaaggt tgccacctgt ctcttaacat ctcactgaac ataagtcctg    480

aggtattagg acgaccatac tgcctctgag ctgaaaacat tcaaaagttc acatccctgt    540

ttgggggata ccattcaccg ccttcagccc agatgatact ttcctttaaa tctgtgtctc    600

tgtgtgtata acaaagagga agatggaaac aatgttcatg gaaactgctg ttgagcccct    660

tgtcccacca ctcccgccat ctgctgcagg caggaaggca tgtgagtgta cgttttcttc    720

caggagacat caggtccccc tggattcaaa ttaagtgcaa tattttgcaa acagctcttc    780

ttagggaaat ctcctgaagg aaaaaaatgt gacagaatgt tccatagtct gagagaatgg    840

aatcgttgag catttagtac aagtccagtg tgtgtgagcg ggacttaggc agctcaagct    900

tgcttttttt tttaagcgta caattgagtg gttttagtaa attcacaaac ttgttcaacc    960

atcaccacta tctaattcca gactcacgct tttttaaaca ataaatgtca tttcatg      1017


<210>  8117
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  8117

Met Glu Thr Met Phe Met Glu Thr Ala Val Glu Pro Leu Val Pro Pro 
1               5                   10                  15


Leu Pro Pro Ser Ala Ala Gly Arg Lys Ala Cys Glu Cys Thr Phe Ser 
            20                  25                  30


Ser Arg Arg His Gln Val Pro Leu Asp Ser Asn 
        35                  40


<210>  8118
<211>  1593
<212>  DNA
<213>  Homo sapiens

<400>  8118
gaagaacagc aagacaggca gcctgcctgt gagcgagatc tacagcttca tgaaggagca     60

cttcccctac ttcaagacgg cccccgacgg gtggaagaac tcggtgcggc acaacctgtc    120

tctgaacaag tgcttcgaga aggtggacaa gcaacccagc atcccccgac cccttgacac    180

tcctccgagg cctgagccgc aatgcctgcc cgtgttgagt gagacttctc catcctggat    240

cctggctgcg tgacctcagt gacctgcacc ccattttggg acaccttggt gcattaagga    300

aacaccctgg ggtgaaagcc cttgaattca tcctcatggg aaatggctga gtggatcaaa    360

cctcagccgc agcctccggg ggacaggccc agggcgggaa atggagccgg agaagcttga    420

gcctctctct tggacaggac aagctgaact ctgaaatggg agccggtcca ggtggccttc    480

agccccacct ttccgatagt ctgttagaat tttattagcg cagattcctg ggccatgccg    540

ggtaccgtga ccttgtgtaa atttatttat atttattgtg gcccatccac cccacttctg    600

caaacccatc ccgaggcctc tggaatggga ctccttctcc ctccctacct cccagccatc    660

ctaactccta caggccagag aatgacatct ctaactggct cataatccct tggcagcctg    720

gggctacttt ttagaaccag caagcactgt tgatactgtg aaacatccca ttttttccgt    780

attagagacc agatattttt ctacctgttc atgattcaca tctcttcttg catgtaccta    840

agaggggcgg tgccattgtt tgggggcttg gggggctttc aaaggggaaa atgcgatggg    900

agagggagga actggagggg ggtgcttttg tactgggatt taagacaccc ctgatggaat    960

gaaagccaac tgaaccacgt aaagctcgaa ccacgtggca agtggtggac aaaacttcaa   1020

cgcatgatat ttattggcac ttcctcacct ccctttgccc tgcagctgtt tttatgcttc   1080

tttttctctc cttgctaatt actgactccc caagtggcaa gttccgcaga tagctgggtt   1140

agaagagaga caggggagtg agctagtcaa atgtgaaaaa tgctctccca gcaaagctga   1200

gacaaaattg gagaagctgc agcctcacgc accatccccc tctttccacc agatggatgt   1260

tgacttggtg tctgggagtt cccgaaccct agagccagga tgttctgttt aatcaacagc   1320

tcagccagct gcctgggagt tttggcatta agccccgcct tgaagggcga gctttaagtt   1380

tttcccagtt ctggaacttt ctaccgagta tccaccaccc ttagacacaa tcccagtgct   1440

acccgtctga cctgcactgc tcatctgctt tgtgtaacat gacccctgat aagatgttga   1500

aactgttatt cacaaagact ccgtgtttgg gcaacatcaa gactgtaagt gtagaattga   1560

gcaactgtct tctatcaata aaggctgaat ggc                                1593


<210>  8119
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  8119

Met Lys Glu His Phe Pro Tyr Phe Lys Thr Ala Pro Asp Gly Trp Lys 
1               5                   10                  15


Asn Ser Val Arg His Asn Leu Ser Leu Asn Lys Cys Phe Glu Lys Val 
            20                  25                  30


Asp Lys Gln Pro Ser Ile Pro Arg Pro Leu Asp Thr Pro Pro Arg Pro 
        35                  40                  45


Glu Pro Gln Cys Leu Pro Val Leu Ser Glu Thr Ser Pro Ser Trp Ile 
    50                  55                  60


Leu Ala Ala 
65


<210>  8120
<211>  2958
<212>  DNA
<213>  Homo sapiens

<400>  8120
aaattgcgga acgcgagggg cgagcgcgag ggagcccccc tccggaaccc ctgcccaccc     60

ccggagcgcc ggcagcggcg gccccgcgag gatcggctcc aggagatgat agaaagtgac    120

acctcatcca taatgtcagg aattattcga aactcagggc aaaatcacca cccctctcca    180

caggaataca gggtcaagca gggcaggctt cctggcagag gcggcattgg gctgtcagcc    240

tgagaccctt tcatgcctgg cctgccctgt cctgccctgc cctgccctgc cccacctcct    300

gcccccagct gtctgatcgc catggccctg aagaacagca agacaggcag cctgcctgtg    360

agcgagatct acagcttcat gaaggagcac ttcccctact tcaagacggc ccccgacggg    420

tggaagaact cggtgcggca caacctgtct ctgaacaagt gcttcgagaa ggtggagaac    480

aagatgagcg gctcctcccg caagggctgc ctgtgggctc tgaacctggc ccgcatcgac    540

aagatggagg aggagatgca caagtggaag aggaaggacc tggctgccat ccaccggagt    600

atggccaacc ctgaggagtt ggacaagctg atctccgacc ggcctgaaag ctgccggcgc    660

cccggcaaac cgggggaacc agaggccccc gtgctgactc acgccaccac agtggccgtg    720

gcgcatggct gcctggctgt ctcccagctc ccaccccagc cactgatgac cctgtccctg    780

cagtcagtcc ccctgcacca ccaggtccag ccccaggcac atcttgctcc agactctcca    840

gcaccagccc agaccccgcc actgcacgcc ctgccggacc tcagccccag cccgctcccc    900

caccccgcca tgggaagggc tcctgtagac ttcatcaaca tcagcaccga catgaacact    960

gaggtggatg ccctcgaccc gagcatcatg gacttcgctc tgcaggggaa cctgtgggag   1020

gagatgaagg atgagggatt cagcttggac acactgggcg cctttgcaga ctccccgctt   1080

ggctgtgacc tgggggcctc aggcctaacc cctgcctcgg gtggcagcga ccagtccttc   1140

ccagacttgc aggtgacggg tctctacaca gcgtactcca ctccggacag tgtggctgca   1200

tcgggcacca gctcctcctc ccagtacctg ggtgcacagg ggaacaagcc tatagccctg   1260

ctttgagctg tcagcctcac ctgccctgga accccggcac ccggcttggg cagagaactg   1320

actagaacag ggtgttccca gaaggcaggt ccctcattgt ccccgaagcc tctcctggac   1380

ctgtggcgaa gttgccggct ggacagggaa gcggttcccc tcagcagccc ctctccttct   1440

cgtgcctccc cctggagctt ccggagcagt ttctgggggc tcttccaagt cagaagaatg   1500

gaggaaggtg gacaagcaac ccagcatccc ccgacccctt gacactcctc cgaggcctga   1560

gccgcaatgc ctgcccgtgt tgagtgagac ttctccatcc tggatcctgg ctgcgtgacc   1620

tcagtgacct gcaccccatt ttgggacacc ttggtgcatt aaggaaacac cctggggtga   1680

aagcccttga attcatcctc atgggaaatg gctgagtgga tcaaacctca gccgcagcct   1740

ccgggggaca ggcccagggc gggaaatgga gccggagaag cttgagcctc tctcttggac   1800

aggacaagct gaactctgaa atgggagccg gtccaggtgg ccttcagccc cacctttccg   1860

atagtctgtt agaattttat tagcgcagat tcctgggcca tgccgggtac cgtgaccttg   1920

tgtaaattta tttatattta ttgtggccca tccaccccac ttctgcaaac ccatcccgag   1980

gcctctggaa tgggactcct tctccctccc tacctcccag ccatcctaac tcctacaggc   2040

cagagaatga catctctaac tggctcataa tcccttggca gcctggggct actttttaga   2100

accagcaagc actgttgata ctgtgaaaca tcccattttt tccgtattag agaccagata   2160

tttttctacc tgttcatgat tcacatctct tcttgcatgt acctaagagg ggcggtgcca   2220

ttgtttgggg gcttgggggg ctttcaaagg ggaaaatgcg atgggagagg gaggaactgg   2280

aggggggtgc ttttgtactg ggatttaaga cacccctgat ggaatgaaag ccaactgaac   2340

cacgtaaagc tcgaaccacg tggcaagtgg tggacaaaac ttcaacgcat gatatttatt   2400

ggcacttcct cacctccctt tgccctgcag ctgtttttat gcttcttttt ctctccttgc   2460

taattactga ctccccaagt ggcaagttcc gcagatagct gggttagaag agagacaggg   2520

gagtgagcta gtcaaatgtg aaaaatgctc tcccagcaaa gctgagacaa aattggagaa   2580

gctgcagcct cacgcaccat ccccctcttt ccaccagatg gatgttgact tggtgtctgg   2640

gagttcccga accctagagc caggatgttc tgtttaatca acagctcagc cagctgcctg   2700

ggagttttgg cattaagccc cgccttgaag ggcgagcttt aagtttttcc cagttctgga   2760

actttctacc gagtatccac cacccttaga cacaatccca gtgctacccg tctgacctgc   2820

actgctcatc tgctttgtgt aacatgaccc ctgataagat gttgaaactg ttattcacaa   2880

agactccgtg tttgggcaac atcaagactg taagtgtaga attgagcaac tgtcttctat   2940

caataaaggc tgaatggc                                                 2958


<210>  8121
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8121

Met Pro Gly Leu Pro Cys Pro Ala Leu Pro Cys Pro Ala Pro Pro Pro 
1               5                   10                  15


Ala Pro Ser Cys Leu Ile Ala Met Ala Leu Lys Asn Ser Lys Thr Gly 
            20                  25                  30


Ser Leu Pro Val Ser Glu Ile Tyr Ser Phe Met Lys Glu His Phe Pro 
        35                  40                  45


Tyr Phe Lys Thr Ala Pro Asp Gly Trp Lys Asn Ser Val Arg His Asn 
    50                  55                  60


Leu Ser Leu Asn Lys Cys Phe Glu Lys Val Glu Asn Lys Met Ser Gly 
65                  70                  75                  80


Ser Ser Arg Lys Gly Cys Leu Trp Ala Leu Asn Leu Ala Arg Ile Asp 
                85                  90                  95


Lys Met Glu Glu Glu Met His Lys Trp Lys Arg Lys Asp Leu Ala Ala 
            100                 105                 110


Ile His Arg Ser Met Ala Asn Pro Glu Glu Leu Asp Lys Leu Ile Ser 
        115                 120                 125


Asp Arg Pro Glu Ser Cys Arg Arg Pro Gly Lys Pro Gly Glu Pro Glu 
    130                 135                 140


Ala Pro Val Leu Thr His Ala Thr Thr Val Ala Val Ala His Gly Cys 
145                 150                 155                 160


Leu Ala Val Ser Gln Leu Pro Pro Gln Pro Leu Met Thr Leu Ser Leu 
                165                 170                 175


Gln Ser Val Pro Leu His His Gln Val Gln Pro Gln Ala His Leu Ala 
            180                 185                 190


Pro Asp Ser Pro Ala Pro Ala Gln Thr Pro Pro Leu His Ala Leu Pro 
        195                 200                 205


Asp Leu Ser Pro Ser Pro Leu Pro His Pro Ala Met Gly Arg Ala Pro 
    210                 215                 220


Val Asp Phe Ile Asn Ile Ser Thr Asp Met Asn Thr Glu Val Asp Ala 
225                 230                 235                 240


Leu Asp Pro Ser Ile Met Asp Phe Ala Leu Gln Gly Asn Leu Trp Glu 
                245                 250                 255


Glu Met Lys Asp Glu Gly Phe Ser Leu Asp Thr Leu Gly Ala Phe Ala 
            260                 265                 270


Asp Ser Pro Leu Gly Cys Asp Leu Gly Ala Ser Gly Leu Thr Pro Ala 
        275                 280                 285


Ser Gly Gly Ser Asp Gln Ser Phe Pro Asp Leu Gln Val Thr Gly Leu 
    290                 295                 300


Tyr Thr Ala Tyr Ser Thr Pro Asp Ser Val Ala Ala Ser Gly Thr Ser 
305                 310                 315                 320


Ser Ser Ser Gln Tyr Leu Gly Ala Gln Gly Asn Lys Pro Ile Ala Leu 
                325                 330                 335


Leu 



<210>  8122
<211>  2345
<212>  DNA
<213>  Homo sapiens

<400>  8122
ggggacctgc agtcgctgtc gtggctcacg gcggtggatg tgcctcggct gcagcagatg     60

gcaagtggcc gcgtggacct gggtggcccc tgcgtgccac atccacaccc aggtgccttg    120

gctggggtgg ccgacctgca tgtgggagcc actccaagtc cccttctcca tggcccagca    180

ggcatggccc cccgaggcat gccaggtctg ggccccataa ctggccacag agacagccag    240

atgagccagt tccccgtggg gggccagccc tcatctggcc tgcaggaccc gccgcatctg    300

tactcacctg ccacccaacc acagttcccg ctccccccgg gtgcccagca gtgccctcct    360

gtgggcctct atggcccccc atttggggtg cggcccccct acccccagcc ccacgtggct    420

gtgcattcat ctcaagaact gcaccccaaa cactacccca agcccatcta ctcgtacagc    480

tgtctgatcg ccatggccct gaagaacagc aagacaggca gcctgcctgt gagcgagatc    540

tacagcttca tgaaggagca cttcccctac ttcaagacgg cccccgacgg gtggaagaac    600

tcggtgcggc acaacctgtc tctgaacaag tgcttcgaga aggtggagaa caagatgagc    660

ggctcctccc gcaagggctg cctgtgggct ctgaacctgg cccgcatcga caagatggag    720

gaggagatgc acaagtggaa gaggaaggac ctggctgcca tccaccggag tatggccaac    780

cctgaggagt tggacaagct gatctccgac cggcctgaaa gctgccggcg ccccggcaaa    840

ccgggggaac cagaggcccc cgtgctgact cacgccacca cagtggccgt ggcgcatggc    900

tgcctggctg tctcccagct cccaccccag ccactgatga ccctgtccct gcagtcagtc    960

cccctgcacc accaggtcca gccccaggca catcttgctc cagactctcc agcaccagcc   1020

cagaccccgc cactgcacgc cctgccggac ctcagcccca gcccgctccc ccaccccgcc   1080

atgggaaggg ctcctgtaga cttcatcaac atcagcaccg acatgaacac tgaggtggat   1140

gccctcgacc cgagcatcat ggacttcgct ctgcagggga acctgtggga ggagatgaag   1200

gatgagggat tcagcttgga cacactgggc gcctttgcag actccccgct tggctgtgac   1260

ctgggggcct caggcctaac ccctgcctcg ggtggcagcg accagtcctt cccagacttg   1320

caggtgacgg gtctctacac agcgtactcc actccggaca gtgtggctgc atcgggcacc   1380

agctcctcct cccagtacct gggtgcacag gggaacaagc ctatagccct gctttgagct   1440

gtcagcctca cctgccctgg aaccccggca cccggcttgg gcagagaact gactagaaca   1500

gggtgttccc agaaggcagg tccctcattg tccccgaagc ctctcctgga cctgtggcga   1560

agttgccggc tggacaggga agcggttccc ctcagcagcc cctctccttc tcgtgcctcc   1620

ccctggagct tccggagcag tttctggggg ctcttccaag tcagaagaat ggaggaaggt   1680

ggacaagcaa cccagcatcc cccgacccct tgacactcct ccgaggcctg agccgcaatg   1740

cctgcccgtg ttgagtgaga cttctccatc ctggatcctg gctgcgtgac ctcagtgacc   1800

tgcaccccat tttgggacac cttggtgcat taaggaaaca ccctggggtg aaagcccttg   1860

aattcatcct catgggaaat ggctgagtgg atcaaacctc agccgcagcc tccgggggac   1920

aggcccaggg cgggaaatgg agccggagaa gcttgagcct ctctcttgga caggacaagc   1980

tgaactctga aatgggagcc ggtccaggtg gccttcagcc ccacctttcc gatagtctgt   2040

tagaatttta ttagcgcaga ttcctgggcc atgccgggta ccgtgacctt gtgtaaattt   2100

atttatattt attgtggccc atccacccca cttctgcaaa cccatcccga ggcctctgga   2160

atgggactcc ttctccctcc ctacctccca gccatcctaa ctcctacagg ccagagaatg   2220

acatctctaa ctggctcata atcccttggc agcctggggc tactttttag aaccagcaag   2280

cactgttgat actgtgaaac atcccatttt ttccgtatta gagaccagat atttttctac   2340

ctgtt                                                               2345


<210>  8123
<211>  459
<212>  PRT
<213>  Homo sapiens

<400>  8123

Met Ala Ser Gly Arg Val Asp Leu Gly Gly Pro Cys Val Pro His Pro 
1               5                   10                  15


His Pro Gly Ala Leu Ala Gly Val Ala Asp Leu His Val Gly Ala Thr 
            20                  25                  30


Pro Ser Pro Leu Leu His Gly Pro Ala Gly Met Ala Pro Arg Gly Met 
        35                  40                  45


Pro Gly Leu Gly Pro Ile Thr Gly His Arg Asp Ser Gln Met Ser Gln 
    50                  55                  60


Phe Pro Val Gly Gly Gln Pro Ser Ser Gly Leu Gln Asp Pro Pro His 
65                  70                  75                  80


Leu Tyr Ser Pro Ala Thr Gln Pro Gln Phe Pro Leu Pro Pro Gly Ala 
                85                  90                  95


Gln Gln Cys Pro Pro Val Gly Leu Tyr Gly Pro Pro Phe Gly Val Arg 
            100                 105                 110


Pro Pro Tyr Pro Gln Pro His Val Ala Val His Ser Ser Gln Glu Leu 
        115                 120                 125


His Pro Lys His Tyr Pro Lys Pro Ile Tyr Ser Tyr Ser Cys Leu Ile 
    130                 135                 140


Ala Met Ala Leu Lys Asn Ser Lys Thr Gly Ser Leu Pro Val Ser Glu 
145                 150                 155                 160


Ile Tyr Ser Phe Met Lys Glu His Phe Pro Tyr Phe Lys Thr Ala Pro 
                165                 170                 175


Asp Gly Trp Lys Asn Ser Val Arg His Asn Leu Ser Leu Asn Lys Cys 
            180                 185                 190


Phe Glu Lys Val Glu Asn Lys Met Ser Gly Ser Ser Arg Lys Gly Cys 
        195                 200                 205


Leu Trp Ala Leu Asn Leu Ala Arg Ile Asp Lys Met Glu Glu Glu Met 
    210                 215                 220


His Lys Trp Lys Arg Lys Asp Leu Ala Ala Ile His Arg Ser Met Ala 
225                 230                 235                 240


Asn Pro Glu Glu Leu Asp Lys Leu Ile Ser Asp Arg Pro Glu Ser Cys 
                245                 250                 255


Arg Arg Pro Gly Lys Pro Gly Glu Pro Glu Ala Pro Val Leu Thr His 
            260                 265                 270


Ala Thr Thr Val Ala Val Ala His Gly Cys Leu Ala Val Ser Gln Leu 
        275                 280                 285


Pro Pro Gln Pro Leu Met Thr Leu Ser Leu Gln Ser Val Pro Leu His 
    290                 295                 300


His Gln Val Gln Pro Gln Ala His Leu Ala Pro Asp Ser Pro Ala Pro 
305                 310                 315                 320


Ala Gln Thr Pro Pro Leu His Ala Leu Pro Asp Leu Ser Pro Ser Pro 
                325                 330                 335


Leu Pro His Pro Ala Met Gly Arg Ala Pro Val Asp Phe Ile Asn Ile 
            340                 345                 350


Ser Thr Asp Met Asn Thr Glu Val Asp Ala Leu Asp Pro Ser Ile Met 
        355                 360                 365


Asp Phe Ala Leu Gln Gly Asn Leu Trp Glu Glu Met Lys Asp Glu Gly 
    370                 375                 380


Phe Ser Leu Asp Thr Leu Gly Ala Phe Ala Asp Ser Pro Leu Gly Cys 
385                 390                 395                 400


Asp Leu Gly Ala Ser Gly Leu Thr Pro Ala Ser Gly Gly Ser Asp Gln 
                405                 410                 415


Ser Phe Pro Asp Leu Gln Val Thr Gly Leu Tyr Thr Ala Tyr Ser Thr 
            420                 425                 430


Pro Asp Ser Val Ala Ala Ser Gly Thr Ser Ser Ser Ser Gln Tyr Leu 
        435                 440                 445


Gly Ala Gln Gly Asn Lys Pro Ile Ala Leu Leu 
    450                 455


<210>  8124
<211>  2217
<212>  DNA
<213>  Homo sapiens

<400>  8124
ggggacctgc agtcgctgtc gtggctcacg gcggtggatg tgcctcggct gcagcagatg     60

gcaagtggcc gcgtggacct gggtggcccc tgcgtgccac atccacaccc aggtgccttg    120

gctggggtgg ccgacctgca tgtgggagcc actccaagtc cccttctcca tggcccagca    180

ggcatggccc cccgaggcat gccaggtctg ggccccataa ctggccacag agacagccag    240

atgagccagt tccccgtggg gggccagccc tcatctggcc tgcaggaccc gccgcatctg    300

tactcacctg ccacccaacc acagttcccg ctccccccgg gtgcccagca gctgtctgat    360

cgccatggcc ctgaagaaca gcaagacagg cagcctgcct gtgagcgaga tctacagctt    420

catgaaggag cacttcccct acttcaagac ggcccccgac gggtggaaga actcggtgcg    480

gcacaacctg tctctgaaca agtgcttcga gaaggtggag aacaagatga gcggctcctc    540

ccgcaagggc tgcctgtggg ctctgaacct ggcccgcatc gacaagatgg aggaggagat    600

gcacaagtgg aagaggaagg acctggctgc catccaccgg agtatggcca accctgagga    660

gttggacaag ctgatctccg accggcctga aagctgccgg cgccccggca aaccggggga    720

accagaggcc cccgtgctga ctcacgccac cacagtggcc gtggcgcatg gctgcctggc    780

tgtctcccag ctcccacccc agccactgat gaccctgtcc ctgcagtcag tccccctgca    840

ccaccaggtc cagccccagg cacatcttgc tccagactct ccagcaccag cccagacccc    900

gccactgcac gccctgccgg acctcagccc cagcccgctc ccccaccccg ccatgggaag    960

ggctcctgta gacttcatca acatcagcac cgacatgaac actgaggtgg atgccctcga   1020

cccgagcatc atggacttcg ctctgcaggg gaacctgtgg gaggagatga aggatgaggg   1080

attcagcttg gacacactgg gcgcctttgc agactccccg cttggctgtg acctgggggc   1140

ctcaggccta acccctgcct cgggtggcag cgaccagtcc ttcccagact tgcaggtgac   1200

gggtctctac acagcgtact ccactccgga cagtgtggct gcatcgggca ccagctcctc   1260

ctcccagtac ctgggtgcac aggggaacaa gcctatagcc ctgctttgag ctgtcagcct   1320

cacctgccct ggaaccccgg cacccggctt gggcagagaa ctgactagaa cagggtgttc   1380

ccagaaggca ggtccctcat tgtccccgaa gcctctcctg gacctgtggc gaagttgccg   1440

gctggacagg gaagcggttc ccctcagcag cccctctcct tctcgtgcct ccccctggag   1500

cttccggagc agtttctggg ggctcttcca agtcagaaga atggaggaag gtggacaagc   1560

aacccagcat cccccgaccc cttgacactc ctccgaggcc tgagccgcaa tgcctgcccg   1620

tgttgagtga gacttctcca tcctggatcc tggctgcgtg acctcagtga cctgcacccc   1680

attttgggac accttggtgc attaaggaaa caccctgggg tgaaagccct tgaattcatc   1740

ctcatgggaa atggctgagt ggatcaaacc tcagccgcag cctccggggg acaggcccag   1800

ggcgggaaat ggagccggag aagcttgagc ctctctcttg gacaggacaa gctgaactct   1860

gaaatgggag ccggtccagg tggccttcag ccccaccttt ccgatagtct gttagaattt   1920

tattagcgca gattcctggg ccatgccggg taccgtgacc ttgtgtaaat ttatttatat   1980

ttattgtggc ccatccaccc cacttctgca aacccatccc gaggcctctg gaatgggact   2040

ccttctccct ccctacctcc cagccatcct aactcctaca ggccagagaa tgacatctct   2100

aactggctca taatcccttg gcagcctggg gctacttttt agaaccagca agcactgttg   2160

atactgtgaa acatcccatt ttttccgtat tagagaccag atatttttct acctgtt      2217


<210>  8125
<211>  314
<212>  PRT
<213>  Homo sapiens

<400>  8125

Met Ala Leu Lys Asn Ser Lys Thr Gly Ser Leu Pro Val Ser Glu Ile 
1               5                   10                  15


Tyr Ser Phe Met Lys Glu His Phe Pro Tyr Phe Lys Thr Ala Pro Asp 
            20                  25                  30


Gly Trp Lys Asn Ser Val Arg His Asn Leu Ser Leu Asn Lys Cys Phe 
        35                  40                  45


Glu Lys Val Glu Asn Lys Met Ser Gly Ser Ser Arg Lys Gly Cys Leu 
    50                  55                  60


Trp Ala Leu Asn Leu Ala Arg Ile Asp Lys Met Glu Glu Glu Met His 
65                  70                  75                  80


Lys Trp Lys Arg Lys Asp Leu Ala Ala Ile His Arg Ser Met Ala Asn 
                85                  90                  95


Pro Glu Glu Leu Asp Lys Leu Ile Ser Asp Arg Pro Glu Ser Cys Arg 
            100                 105                 110


Arg Pro Gly Lys Pro Gly Glu Pro Glu Ala Pro Val Leu Thr His Ala 
        115                 120                 125


Thr Thr Val Ala Val Ala His Gly Cys Leu Ala Val Ser Gln Leu Pro 
    130                 135                 140


Pro Gln Pro Leu Met Thr Leu Ser Leu Gln Ser Val Pro Leu His His 
145                 150                 155                 160


Gln Val Gln Pro Gln Ala His Leu Ala Pro Asp Ser Pro Ala Pro Ala 
                165                 170                 175


Gln Thr Pro Pro Leu His Ala Leu Pro Asp Leu Ser Pro Ser Pro Leu 
            180                 185                 190


Pro His Pro Ala Met Gly Arg Ala Pro Val Asp Phe Ile Asn Ile Ser 
        195                 200                 205


Thr Asp Met Asn Thr Glu Val Asp Ala Leu Asp Pro Ser Ile Met Asp 
    210                 215                 220


Phe Ala Leu Gln Gly Asn Leu Trp Glu Glu Met Lys Asp Glu Gly Phe 
225                 230                 235                 240


Ser Leu Asp Thr Leu Gly Ala Phe Ala Asp Ser Pro Leu Gly Cys Asp 
                245                 250                 255


Leu Gly Ala Ser Gly Leu Thr Pro Ala Ser Gly Gly Ser Asp Gln Ser 
            260                 265                 270


Phe Pro Asp Leu Gln Val Thr Gly Leu Tyr Thr Ala Tyr Ser Thr Pro 
        275                 280                 285


Asp Ser Val Ala Ala Ser Gly Thr Ser Ser Ser Ser Gln Tyr Leu Gly 
    290                 295                 300


Ala Gln Gly Asn Lys Pro Ile Ala Leu Leu 
305                 310


<210>  8126
<211>  900
<212>  DNA
<213>  Homo sapiens

<400>  8126
atgcaaaagg aggaccatgc tatgtcatca agggctgatg cgaagaagaa cccagaagca     60

ggcgtcaata accccccgca cggctactgc gcatgctctg agctggacag ctccagagag    120

ggaaatttaa aaacggttcg agctgcgacg gcggccaaat tgcggaacgc gaggggcgag    180

cgcgagggag cccccctccg gaacccctgc ccacccccgg agcgccggca gcggcggccc    240

cgcgaggatc ggctccagga gatgatagaa agtgacacct catccataat gtcaggaatt    300

attcgaaact cagggcaaaa tcaccacccc tctccacagg aatacaggct tctagccacc    360

accagcgatg atgaccttcc cggggacctg cagtcgctgt cgtggctcac ggcggtggat    420

gtgcctcggc tgcagcagat ggcaagtggc cgcgtggacc tgggtggccc ctgcgtgcca    480

catccacacc caggtgcctt ggctggggtg gccgacctgc atgtgggagc cactccaagt    540

ccccttctcc atggcccagc aggcatggcc ccccgaggca tgccaggtct gggccccata    600

actggccaca gagacagcca gatgagccag ttccccgtgg ggggccagcc ctcatctggc    660

ctgcaggacc cgccgcatct gtactcacct gccacccaac cacagttccc gctccccccg    720

ggtgcccagc aggtaccaag ggctcagggg agccctggac tgagcagcag acaccctgcc    780

ttgggctggc cggggacccc tctgagcctc agtttactca cccagcacat ggggataaca    840

ttccctccat gctcatgtca tggggtcatt cattccgttc ccccaaaact cctgccctga    900


<210>  8127
<211>  299
<212>  PRT
<213>  Homo sapiens

<400>  8127

Met Gln Lys Glu Asp His Ala Met Ser Ser Arg Ala Asp Ala Lys Lys 
1               5                   10                  15


Asn Pro Glu Ala Gly Val Asn Asn Pro Pro His Gly Tyr Cys Ala Cys 
            20                  25                  30


Ser Glu Leu Asp Ser Ser Arg Glu Gly Asn Leu Lys Thr Val Arg Ala 
        35                  40                  45


Ala Thr Ala Ala Lys Leu Arg Asn Ala Arg Gly Glu Arg Glu Gly Ala 
    50                  55                  60


Pro Leu Arg Asn Pro Cys Pro Pro Pro Glu Arg Arg Gln Arg Arg Pro 
65                  70                  75                  80


Arg Glu Asp Arg Leu Gln Glu Met Ile Glu Ser Asp Thr Ser Ser Ile 
                85                  90                  95


Met Ser Gly Ile Ile Arg Asn Ser Gly Gln Asn His His Pro Ser Pro 
            100                 105                 110


Gln Glu Tyr Arg Leu Leu Ala Thr Thr Ser Asp Asp Asp Leu Pro Gly 
        115                 120                 125


Asp Leu Gln Ser Leu Ser Trp Leu Thr Ala Val Asp Val Pro Arg Leu 
    130                 135                 140


Gln Gln Met Ala Ser Gly Arg Val Asp Leu Gly Gly Pro Cys Val Pro 
145                 150                 155                 160


His Pro His Pro Gly Ala Leu Ala Gly Val Ala Asp Leu His Val Gly 
                165                 170                 175


Ala Thr Pro Ser Pro Leu Leu His Gly Pro Ala Gly Met Ala Pro Arg 
            180                 185                 190


Gly Met Pro Gly Leu Gly Pro Ile Thr Gly His Arg Asp Ser Gln Met 
        195                 200                 205


Ser Gln Phe Pro Val Gly Gly Gln Pro Ser Ser Gly Leu Gln Asp Pro 
    210                 215                 220


Pro His Leu Tyr Ser Pro Ala Thr Gln Pro Gln Phe Pro Leu Pro Pro 
225                 230                 235                 240


Gly Ala Gln Gln Val Pro Arg Ala Gln Gly Ser Pro Gly Leu Ser Ser 
                245                 250                 255


Arg His Pro Ala Leu Gly Trp Pro Gly Thr Pro Leu Ser Leu Ser Leu 
            260                 265                 270


Leu Thr Gln His Met Gly Ile Thr Phe Pro Pro Cys Ser Cys His Gly 
        275                 280                 285


Val Ile His Ser Val Pro Pro Lys Leu Leu Pro 
    290                 295


<210>  8128
<211>  712
<212>  DNA
<213>  Homo sapiens

<400>  8128
aaattgtgcg gttaacggtc aaagcccccc tgcctacttt gacactcatt taaagatgac     60

agggaacaat agagatttgt tctgtgcaac cctttcttgt tatgccggcg acatcagctc    120

cgcacatgaa actgcccgat atttcattcc acctgccacc tccctcccgc ctcggtcgac    180

tctctcctct gctactttgc ttgtccccac tttaacacaa agagacagct ctgtgttcac    240

agcacctaac agtgttgaaa aagaatgcta tttaaaaccc gagttgagac atcacctttc    300

caaacccatg actgcttcct ggctcactaa acacgaacca gaaattaatg ctgcaaagag    360

cagagacaag agattcgact gtgttagcca ggatggtctc gatctcctga cttcgtgatc    420

tgcccgcctc agcctcccaa agtgctggga ttacaggctt gagccactgt gcctggcttc    480

aggctgggat ttttatagct tattatggca agggaggaga cggagagtaa aagaagaagg    540

aagagcatac acagtcaccc cttgtgtgac aaatatgcaa gaaataaaga taaatgtgta    600

caattcttac aattttactt ttctgaattt tgctattgca ctgaatgatt tgtgataaga    660

cagatgggga tgaaaaatat acttattaaa taaacagcta ttaaaagccc ct            712


<210>  8129
<211>  120
<212>  PRT
<213>  Homo sapiens

<400>  8129

Met Thr Gly Asn Asn Arg Asp Leu Phe Cys Ala Thr Leu Ser Cys Tyr 
1               5                   10                  15


Ala Gly Asp Ile Ser Ser Ala His Glu Thr Ala Arg Tyr Phe Ile Pro 
            20                  25                  30


Pro Ala Thr Ser Leu Pro Pro Arg Ser Thr Leu Ser Ser Ala Thr Leu 
        35                  40                  45


Leu Val Pro Thr Leu Thr Gln Arg Asp Ser Ser Val Phe Thr Ala Pro 
    50                  55                  60


Asn Ser Val Glu Lys Glu Cys Tyr Leu Lys Pro Glu Leu Arg His His 
65                  70                  75                  80


Leu Ser Lys Pro Met Thr Ala Ser Trp Leu Thr Lys His Glu Pro Glu 
                85                  90                  95


Ile Asn Ala Ala Lys Ser Arg Asp Lys Arg Phe Asp Cys Val Ser Gln 
            100                 105                 110


Asp Gly Leu Asp Leu Leu Thr Ser 
        115                 120


<210>  8130
<211>  2858
<212>  DNA
<213>  Homo sapiens

<400>  8130
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaacaag    600

tggccaatat gatgatcagg atgaagagag agtttacagg aagccagaat tcaatatttc    660

ctgtttttga taatctcttg ttgcttgatc ggaatgtgga tttattaaca cctcttgcca    720

ctcagctgac atatgaagga ctcattgatg aaatttatgg cattcagaac agttatgtga    780

aattacctcc agagaaattt gcacctaaga aacagggcga tggtggtaag gacctcccca    840

cggaagcaaa gaagctgcag ctgaattctg cagaggagct ctatgctgag atccgagata    900

agaacttcaa cgcagttggc tctgtgctca gcaagaaagc aaagatcatc tctgcagcat    960

tcgaggaaag acacaatgct aagaccgtgg gggagatcaa gcagtttgtt tcccagttgc   1020

cccacatgca ggcagcaagg ggctcgcttg caaaccatac ctcaattgca gaattgatca   1080

aagatgtcac tacttctgaa gacttttttg ataaattaac cgtggaacag gagtttatgt   1140

ctggaataga cactgataag gtcaacaatt acattgagga ttgtatcgcc caaaagcact   1200

cgttgatcaa ggtgttaaga ctagtttgcc tccaatccgt gtgtaatagt gggctcaaac   1260

aaaaagtttt ggattattac aaaagagaga ttctccagac atacggctat gagcacatat   1320

tgaccttaca caacctggag aaggccggcc tgctgaaacc gcagacgggg ggcagaaaca   1380

attacccaac tatacggaaa acattacgcc tctggatgga tgatgttaat gagcaaaacc   1440

ccacggacat atcgtatgtg tacagtgggt atgccccgct cagtgtgcgg ctggcccagc   1500

tgctttcccg gcctggctgg cggagcatcg aggaggtcct ccgcatcctc ccagggcccc   1560

actttgagga gcggcagcca ctgcccacag gactgcagaa gaaacgtcaa ccgggagaaa   1620

accgagtgac tctgatattt ttccttgggg gcgtaacctt cgctgaaatt gctgccctgc   1680

gatttctctc ccagttggaa gatggagaaa tcagagcctc attcccttag tagtgaagca   1740

ttgatgagga gagcagtgtc tttggtaaca gatagcacct ctacctttct ctctcagacc   1800

acatatgcgt tgattgaagc tattactgaa tatactaagg ctgtttatac cttaacttct   1860

ctttaccgac aatatacaag tttacttggg aaaatgaatt cagaggagga agatgaagtg   1920

tggcaggtga tcataggagc cagagctgag atgacttcaa aacaccaaga gtacttgaag   1980

ctggaaacca cttggatgac tgcagttggt ctttcagaga tggcagcaga agctgcatat   2040

caaactggcg cagatcaggc ctctataacc gccaggaatc acattcagct ggtgaaactg   2100

caggtggaag aggtgcacca gctctcccgg aaagcagaaa ccaagctggc agaagcacag   2160

atagaagagc tccgtcagaa aacacaggag gaaggggagg agcgggctga gtcggagcag   2220

gaggcctacc tgcgtgagga ttgagggcct gagcacactg ccctgtctcc ccactcagtg   2280

gggaaagcag gggcagatgc caccctgccc agggttggca tgactgtctg tgcaccgaga   2340

agaggcggca gatcctgccc tggccaatca ggcgagacgc ctttgtgagc tgtgagtgcc   2400

tcctgtggtc tcaggcttgc gctggacctg gttcttagcc cttgggcact gcaccctgtt   2460

taacatttca ccccactctg tacagctgct cttacccatt ttttttacct cacacccaaa   2520

gcattttgcc tacctgggtc agagagagga gtcctttttg tcatgccctt aagttcagca   2580

actgtttaac ctgttttcag tcttatttac gtcgtcaaaa atgatttagt acttgttccc   2640

tctgttggga tgccagttgt ggcaggggga ggggaacctg tccagtttgt acgatttctt   2700

tgtatgtatt tctgatgtgt tctctgatct gcccccactg tcctgtgagg acagctgagg   2760

ccaaggagtg aaaaacctat tactactaag agaaggggtg cagagtgttt acctggtgct   2820

ctcaacagga cttaacatca acaggactta acacaggc                           2858


<210>  8131
<211>  538
<212>  PRT
<213>  Homo sapiens

<400>  8131

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Gln Val Ala Asn Met Met Ile Arg Met Lys Arg Glu Phe Thr Gly 
                165                 170                 175


Ser Gln Asn Ser Ile Phe Pro Val Phe Asp Asn Leu Leu Leu Leu Asp 
            180                 185                 190


Arg Asn Val Asp Leu Leu Thr Pro Leu Ala Thr Gln Leu Thr Tyr Glu 
        195                 200                 205


Gly Leu Ile Asp Glu Ile Tyr Gly Ile Gln Asn Ser Tyr Val Lys Leu 
    210                 215                 220


Pro Pro Glu Lys Phe Ala Pro Lys Lys Gln Gly Asp Gly Gly Lys Asp 
225                 230                 235                 240


Leu Pro Thr Glu Ala Lys Lys Leu Gln Leu Asn Ser Ala Glu Glu Leu 
                245                 250                 255


Tyr Ala Glu Ile Arg Asp Lys Asn Phe Asn Ala Val Gly Ser Val Leu 
            260                 265                 270


Ser Lys Lys Ala Lys Ile Ile Ser Ala Ala Phe Glu Glu Arg His Asn 
        275                 280                 285


Ala Lys Thr Val Gly Glu Ile Lys Gln Phe Val Ser Gln Leu Pro His 
    290                 295                 300


Met Gln Ala Ala Arg Gly Ser Leu Ala Asn His Thr Ser Ile Ala Glu 
305                 310                 315                 320


Leu Ile Lys Asp Val Thr Thr Ser Glu Asp Phe Phe Asp Lys Leu Thr 
                325                 330                 335


Val Glu Gln Glu Phe Met Ser Gly Ile Asp Thr Asp Lys Val Asn Asn 
            340                 345                 350


Tyr Ile Glu Asp Cys Ile Ala Gln Lys His Ser Leu Ile Lys Val Leu 
        355                 360                 365


Arg Leu Val Cys Leu Gln Ser Val Cys Asn Ser Gly Leu Lys Gln Lys 
    370                 375                 380


Val Leu Asp Tyr Tyr Lys Arg Glu Ile Leu Gln Thr Tyr Gly Tyr Glu 
385                 390                 395                 400


His Ile Leu Thr Leu His Asn Leu Glu Lys Ala Gly Leu Leu Lys Pro 
                405                 410                 415


Gln Thr Gly Gly Arg Asn Asn Tyr Pro Thr Ile Arg Lys Thr Leu Arg 
            420                 425                 430


Leu Trp Met Asp Asp Val Asn Glu Gln Asn Pro Thr Asp Ile Ser Tyr 
        435                 440                 445


Val Tyr Ser Gly Tyr Ala Pro Leu Ser Val Arg Leu Ala Gln Leu Leu 
    450                 455                 460


Ser Arg Pro Gly Trp Arg Ser Ile Glu Glu Val Leu Arg Ile Leu Pro 
465                 470                 475                 480


Gly Pro His Phe Glu Glu Arg Gln Pro Leu Pro Thr Gly Leu Gln Lys 
                485                 490                 495


Lys Arg Gln Pro Gly Glu Asn Arg Val Thr Leu Ile Phe Phe Leu Gly 
            500                 505                 510


Gly Val Thr Phe Ala Glu Ile Ala Ala Leu Arg Phe Leu Ser Gln Leu 
        515                 520                 525


Glu Asp Gly Glu Ile Arg Ala Ser Phe Pro 
    530                 535


<210>  8132
<211>  4589
<212>  DNA
<213>  Homo sapiens

<400>  8132
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaagagt    600

gctacctgga gggtgaccag acgagcctgt accacgcagc caaggggctg atgaccctgc    660

aagctctgta tggaacgatc ccccagatct ttgggaaagg agaatgcgct cggcaagtgg    720

ccaatatgat gatcaggatg aagagagagt ttacaggaag ccagaattca atatttcctg    780

tttttgataa tctcttgttg cttgatcgga atgtggattt attaacacct cttgccactc    840

agctgacata tgaaggactc attgatgaaa tttatggcat tcagaacagt tatgtgaaat    900

tacctccaga gaaatttgca cctaagaaac agggcgatgg tggtaaggac ctccccacgg    960

aagcaaagaa gctgcagctg aattctgcag aggagctcta tgctgagatc cgagataaga   1020

acttcaacgc agttggctct gtgctcagca agaaagcaaa gatcatctct gcagcattcg   1080

aggaaagaca caatgctaag accgtggggg agatcaagca gtttgtttcc cagttgcccc   1140

acatgcaggc agcaaggggc tcgcttgcaa accatacctc aattgcagaa ttgatcaaag   1200

atgtcactac ttctgaagac ttttttgata aattaaccgt ggaacaggag tttatgtctg   1260

gaatagacac tgataaggtc aacaattaca ttgaggattg tatcgcccaa aagcactcgt   1320

tgatcaaggt gttaagacta gtttgcctcc aatccgtgtg taatagtggg ctcaaacaaa   1380

aagttttgga ttattacaaa agagagattc tccagacata cggctatgag cacatattga   1440

ccttacacaa cctggagaag gccggcctgc tgaaaccgca gacggggggc agaaacaatt   1500

acccaactat acggaaaaca ttacgcctct ggatggatga tgttaatgag caaaacccca   1560

cggacatatc gtatgtgtac agtgggtatg ccccgctcag tgtgcggctg gcccagctgc   1620

tttcccggcc tggctggcgg agcatcgagg aggtcctccg catcctccca gggccccact   1680

ttgaggagcg gcagccactg cccacaggac tgcagaagaa acgtcaaccg ggagaaaacc   1740

gagtgactct gatatttttc cttgggggcg taaccttcgc tgaaattgct gccctgcgat   1800

ttctctccca gttggaagat ggaggtacag aatatgtcat tgccaccact aaactaatga   1860

atggaaccag ttggatagag gctctgatgg aaaaaccttt ctaggatgtt cagaggagac   1920

ttaacaagtg tactgcagaa taaactacct ctttgaagaa attgctgaaa ggaagtaaaa   1980

ccccatagaa gaaacatggg aatacagaat atattctggg gtcagcttct taaattatac   2040

tactgtttac tgctttctcc gtctcttttg tattcccttt ttttttttcc tttgagacgg   2100

agtcttgctc tgtcacccag actagagtgc agtggcacgg tctcacctca ctgcaacctc   2160

cacctcctag gttcaagcaa ttctcctgcc tcagcctcct gagtagctgg gactacaggc   2220

atgcaccacc acacccggct aatttttgta tttttagtag ccatggtgtt tcaccatgtt   2280

ggccaggctg gtctcaaact cctgacctca ggtgatccac ctgcctcggc ctcccacagt   2340

gctgggatta caggcctgag ccaccgtgcc tggcccctaa tctgctgaag aaagaagaat   2400

agaagaaaat caacctgagt aaaagcagca ctggttttga gttttctaag ctcagggtct   2460

tcattagaga cctctggaaa tacattaagg atggtggggg tagataatcc attcagccag   2520

acaaacgggg ccagctctta aaataagaaa gctgagactg aggaggtgaa actgaaaata   2580

aaaagagaaa gttcatcctc taatccccag tgctgtattt cttcaaggcg catcaggcct   2640

aggacagtgg ttaagtgttg ggagctggag atcattttat cactgagttg agatttcttt   2700

ttcctgcaga gtgtgggaga ttatatttag ggtcatcagt cactgtcgca actgatcact   2760

aaggcaagtt tgcttccttc tacttcttac aaagcaagag gtttagggga gcttcttgcc   2820

cagaaacaaa gtttatgctc tatgtgatca gctacatctc cttaggttcc atacttatca   2880

ggggcttttg acatggaaga atgtgataat tggggagcaa ccttctgaga attcagcctt   2940

tgaagtaatt caaagacagt ttcttagcac acacgttaac tccagacaca gcagtggtgg   3000

gtgcctccat tgaggtttcc gttttctctt ctgtccatca agggcccaac atccaactgg   3060

tcccacagtg agcaggggca actcttgctt cttcagcatc tggccacttc gtttccatgg   3120

taactgccac gtgtactttt ctagcagtct gtggccactc cgtactcagc tgaaaacact   3180

gtttcagccc cctctctggt gacctcagcc ttctccaggt gtatctcttg atgatcttgg   3240

agaccagcag ccacagctgc tgctactcct gcaggagact gtcaggctgt ggtggggggc   3300

aggggtgttg gaggagaagt tgaaaatccg tgtgttctct gcccctctgc tcctccatct   3360

tagcttctgg aggagttaag gcaccaaggg caccaagtca ggttggcagt tttgctgccc   3420

ttgcccaagc ctccagcaaa actagctggt cccctgcttt gctgggtccc agccaggtgt   3480

gattttggtt gttgattagt aaccacacat tgtttttccc cacctttttc attagtggag   3540

gtttttgttt tgttttgttt ttgtttgttt gagacagagt ctcacgctct tttcagactg   3600

gagtgcagtg gtgcgatgtc agctcactgc aacctccact tcccgggttc agacgattct   3660

catgcctcag cctcctgagt agctgggatt acagatgtgc accaccacac ctggctaatt   3720

tttgtatttt tagtagagat ggggtttcac catattggcc aggctggtct caaactcctg   3780

acctcaggcg attggcccac ctcggcctcc caaagtgctg ggattacagg tgtgaaccac   3840

cgtgcccggc ccattagtgg agttctgatg ggcacggtaa atattattaa tgaaagagaa   3900

attctgtata cttttttaaa aatctcttta atgaaagaat gaagagtggc agagataata   3960

attgaaagat tagtttctca tggaattaat ttggccttga tattcagtat ttggaaatgt   4020

cttaaagaaa accattttca ttgtagaaaa tcctttttta aatacttgtt atatcccagg   4080

gagattagtt tataccttcc acctcaggca gtcatcagct gctttagaga atggaatcca   4140

ccctgcccct ccattttttg gttcctgggg ctcaattcaa gtctggtcaa gtctccctgg   4200

ctggggattc tgtcctggga acagatactc agttgtagtc tcatgtgtct gcactcaccc   4260

aagactctat atacttgctt gctcagagca tagttagggc agctcctaaa aatgcattca   4320

gcagaagact gaaaaacttc aattgcttca tttgtatgca aatagaaaat ggtagataat   4380

tatatattat acgcctttgt gtaagttcat ttaatacttg aagcagtctt tgtctcaaaa   4440

gagtatgccc ttactgagaa aggatatgtg aacggtacat ttattgttgg ggagagtgga   4500

ttgtttacat catgtctgga cttttgtcta gttgggtaga cagttctaca ccagcagccc   4560

ccttaataaa gaagtctaca cagacactg                                     4589


<210>  8133
<211>  596
<212>  PRT
<213>  Homo sapiens

<400>  8133

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Glu Cys Tyr Leu Glu Gly Asp Gln Thr Ser Leu Tyr His Ala Ala 
                165                 170                 175


Lys Gly Leu Met Thr Leu Gln Ala Leu Tyr Gly Thr Ile Pro Gln Ile 
            180                 185                 190


Phe Gly Lys Gly Glu Cys Ala Arg Gln Val Ala Asn Met Met Ile Arg 
        195                 200                 205


Met Lys Arg Glu Phe Thr Gly Ser Gln Asn Ser Ile Phe Pro Val Phe 
    210                 215                 220


Asp Asn Leu Leu Leu Leu Asp Arg Asn Val Asp Leu Leu Thr Pro Leu 
225                 230                 235                 240


Ala Thr Gln Leu Thr Tyr Glu Gly Leu Ile Asp Glu Ile Tyr Gly Ile 
                245                 250                 255


Gln Asn Ser Tyr Val Lys Leu Pro Pro Glu Lys Phe Ala Pro Lys Lys 
            260                 265                 270


Gln Gly Asp Gly Gly Lys Asp Leu Pro Thr Glu Ala Lys Lys Leu Gln 
        275                 280                 285


Leu Asn Ser Ala Glu Glu Leu Tyr Ala Glu Ile Arg Asp Lys Asn Phe 
    290                 295                 300


Asn Ala Val Gly Ser Val Leu Ser Lys Lys Ala Lys Ile Ile Ser Ala 
305                 310                 315                 320


Ala Phe Glu Glu Arg His Asn Ala Lys Thr Val Gly Glu Ile Lys Gln 
                325                 330                 335


Phe Val Ser Gln Leu Pro His Met Gln Ala Ala Arg Gly Ser Leu Ala 
            340                 345                 350


Asn His Thr Ser Ile Ala Glu Leu Ile Lys Asp Val Thr Thr Ser Glu 
        355                 360                 365


Asp Phe Phe Asp Lys Leu Thr Val Glu Gln Glu Phe Met Ser Gly Ile 
    370                 375                 380


Asp Thr Asp Lys Val Asn Asn Tyr Ile Glu Asp Cys Ile Ala Gln Lys 
385                 390                 395                 400


His Ser Leu Ile Lys Val Leu Arg Leu Val Cys Leu Gln Ser Val Cys 
                405                 410                 415


Asn Ser Gly Leu Lys Gln Lys Val Leu Asp Tyr Tyr Lys Arg Glu Ile 
            420                 425                 430


Leu Gln Thr Tyr Gly Tyr Glu His Ile Leu Thr Leu His Asn Leu Glu 
        435                 440                 445


Lys Ala Gly Leu Leu Lys Pro Gln Thr Gly Gly Arg Asn Asn Tyr Pro 
    450                 455                 460


Thr Ile Arg Lys Thr Leu Arg Leu Trp Met Asp Asp Val Asn Glu Gln 
465                 470                 475                 480


Asn Pro Thr Asp Ile Ser Tyr Val Tyr Ser Gly Tyr Ala Pro Leu Ser 
                485                 490                 495


Val Arg Leu Ala Gln Leu Leu Ser Arg Pro Gly Trp Arg Ser Ile Glu 
            500                 505                 510


Glu Val Leu Arg Ile Leu Pro Gly Pro His Phe Glu Glu Arg Gln Pro 
        515                 520                 525


Leu Pro Thr Gly Leu Gln Lys Lys Arg Gln Pro Gly Glu Asn Arg Val 
    530                 535                 540


Thr Leu Ile Phe Phe Leu Gly Gly Val Thr Phe Ala Glu Ile Ala Ala 
545                 550                 555                 560


Leu Arg Phe Leu Ser Gln Leu Glu Asp Gly Gly Thr Glu Tyr Val Ile 
                565                 570                 575


Ala Thr Thr Lys Leu Met Asn Gly Thr Ser Trp Ile Glu Ala Leu Met 
            580                 585                 590


Glu Lys Pro Phe 
        595


<210>  8134
<211>  2601
<212>  DNA
<213>  Homo sapiens

<400>  8134
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaagagt    600

gctacctgga gggtgaccag acgagcctgt accacgcagc caaggggctg atgaccctgc    660

aagctctgta tggaacgatc ccccagatct ttgggaaagg agaatgcgct cggcaagtgg    720

ccaatatgat gatcaggatg aagagagagt ttacaggaag ccagaattca atatttcctg    780

tttttgataa tctcttgttg cttgatcgga atgtggattt attaacacct cttgccactc    840

agctgacata tgaaggactc attgatgaaa tttatggcat tcagaacagt tatgtgaaat    900

tacctccaga gaaatttgca cctaagaaac agggcgatgg tggtaaggac ctccccacgg    960

aagcaaagaa gctgcagctg aattctgcag aggagctcta tgctgagatc cgagataaga   1020

acttcaacgc agttggctct gtgctcagca agaaagcaaa gatcatctct gcagcattcg   1080

aggaaagaca caatgctaag accgtggggg agatcaagca gtttgtttcc cagttgcccc   1140

acatgcaggc agcaaggggc tcgcttgcaa accatacctc aattgcagaa ttgatcaaag   1200

atgtcactac ttctgaagac ttttttgata aattaaccgt ggaacaggag tttatgtctg   1260

gaatagacac tgataaggtc aacaattaca ttgaggattg tatcgcccaa aagcactcgt   1320

tgatcaaggt gttaagacta gtttgcctcc aatccgtgtg taatagtggg ctcaaacaaa   1380

aagttttgga ttattacaaa agagagattc tccagacata cggctatgag cacatattga   1440

ccttacacaa cctggagaag gccggcctgc tgaaaccgca gacggggggc agaaacaatt   1500

acccaactat acggaaaaca ttacgcctct ggatggatga tgttaatgag caaaacccca   1560

cggacatatc gtatgtgtac agtgggtatg ccccgctcag tgtgcggctg gcccagctgc   1620

tttcccggcc tggctggcgg agcatcgagg aggtcctccg catcctccca gggccccact   1680

ttgaggagcg gcagccactg cccacaggac tgcagaagaa acgtcaaccg ggagaaaacc   1740

gagtgactct gatatttttc cttgggggcg taaccttcgc tgaaattgct gccctgcgat   1800

ttctctccca gttggaagat ggaggtacag aatatgtcat tgccaccact aaactaatga   1860

atggaaccag ttggatagag gctctgatgg aaaaaccttt ctaggatgtt cagaggagac   1920

ttaacaagtg tactgcagaa taaactacct ctttgaagaa attgctgaaa ggaagtaaaa   1980

ccccatagaa gaaacatggg aatacagaat atattctggg gtcagcttct taaattatac   2040

tactgtttac tgctttctcc gtctcttttg tattcccttt ttttttttcc tttgagacgg   2100

agtcttgctc tgtcacccag actagagtgc agtggcacgg tctcacctca ctgcaacctc   2160

cacctcctag gttcaagcaa ttctcctgcc tcagcctcct gagtagctgg gactacaggc   2220

atgcaccacc acacccggct aatttttgta tttttagtag ccatggtgtt tcaccatgtt   2280

ggccaggctg gtctcaaact cctgacctca ggtgatccac ctgcctcggc ctcccacagt   2340

gctgggatta caggcctgag ccaccgtgcc tggcccctaa tctgctgaag aaagaagaat   2400

agaagaaaat caacctgagt aaaagcagca ctggttttga gttttctaag ctcagggtct   2460

tcattagaga cctctggaaa tacattaagg atggtggggg tagataatcc attcagccag   2520

acaaacgggg ccagctctta aaataagaaa gctgagactg aggaggtgaa actgaaaata   2580

aaaagagaaa gttcatcctc t                                             2601


<210>  8135
<211>  596
<212>  PRT
<213>  Homo sapiens

<400>  8135

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Glu Cys Tyr Leu Glu Gly Asp Gln Thr Ser Leu Tyr His Ala Ala 
                165                 170                 175


Lys Gly Leu Met Thr Leu Gln Ala Leu Tyr Gly Thr Ile Pro Gln Ile 
            180                 185                 190


Phe Gly Lys Gly Glu Cys Ala Arg Gln Val Ala Asn Met Met Ile Arg 
        195                 200                 205


Met Lys Arg Glu Phe Thr Gly Ser Gln Asn Ser Ile Phe Pro Val Phe 
    210                 215                 220


Asp Asn Leu Leu Leu Leu Asp Arg Asn Val Asp Leu Leu Thr Pro Leu 
225                 230                 235                 240


Ala Thr Gln Leu Thr Tyr Glu Gly Leu Ile Asp Glu Ile Tyr Gly Ile 
                245                 250                 255


Gln Asn Ser Tyr Val Lys Leu Pro Pro Glu Lys Phe Ala Pro Lys Lys 
            260                 265                 270


Gln Gly Asp Gly Gly Lys Asp Leu Pro Thr Glu Ala Lys Lys Leu Gln 
        275                 280                 285


Leu Asn Ser Ala Glu Glu Leu Tyr Ala Glu Ile Arg Asp Lys Asn Phe 
    290                 295                 300


Asn Ala Val Gly Ser Val Leu Ser Lys Lys Ala Lys Ile Ile Ser Ala 
305                 310                 315                 320


Ala Phe Glu Glu Arg His Asn Ala Lys Thr Val Gly Glu Ile Lys Gln 
                325                 330                 335


Phe Val Ser Gln Leu Pro His Met Gln Ala Ala Arg Gly Ser Leu Ala 
            340                 345                 350


Asn His Thr Ser Ile Ala Glu Leu Ile Lys Asp Val Thr Thr Ser Glu 
        355                 360                 365


Asp Phe Phe Asp Lys Leu Thr Val Glu Gln Glu Phe Met Ser Gly Ile 
    370                 375                 380


Asp Thr Asp Lys Val Asn Asn Tyr Ile Glu Asp Cys Ile Ala Gln Lys 
385                 390                 395                 400


His Ser Leu Ile Lys Val Leu Arg Leu Val Cys Leu Gln Ser Val Cys 
                405                 410                 415


Asn Ser Gly Leu Lys Gln Lys Val Leu Asp Tyr Tyr Lys Arg Glu Ile 
            420                 425                 430


Leu Gln Thr Tyr Gly Tyr Glu His Ile Leu Thr Leu His Asn Leu Glu 
        435                 440                 445


Lys Ala Gly Leu Leu Lys Pro Gln Thr Gly Gly Arg Asn Asn Tyr Pro 
    450                 455                 460


Thr Ile Arg Lys Thr Leu Arg Leu Trp Met Asp Asp Val Asn Glu Gln 
465                 470                 475                 480


Asn Pro Thr Asp Ile Ser Tyr Val Tyr Ser Gly Tyr Ala Pro Leu Ser 
                485                 490                 495


Val Arg Leu Ala Gln Leu Leu Ser Arg Pro Gly Trp Arg Ser Ile Glu 
            500                 505                 510


Glu Val Leu Arg Ile Leu Pro Gly Pro His Phe Glu Glu Arg Gln Pro 
        515                 520                 525


Leu Pro Thr Gly Leu Gln Lys Lys Arg Gln Pro Gly Glu Asn Arg Val 
    530                 535                 540


Thr Leu Ile Phe Phe Leu Gly Gly Val Thr Phe Ala Glu Ile Ala Ala 
545                 550                 555                 560


Leu Arg Phe Leu Ser Gln Leu Glu Asp Gly Gly Thr Glu Tyr Val Ile 
                565                 570                 575


Ala Thr Thr Lys Leu Met Asn Gly Thr Ser Trp Ile Glu Ala Leu Met 
            580                 585                 590


Glu Lys Pro Phe 
        595


<210>  8136
<211>  2055
<212>  DNA
<213>  Homo sapiens

<400>  8136
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaagagt    600

gctacctgga gggtgaccag acgagcctgt accacgcagc caaggggctg atgaccctgc    660

aagctctgta tggaacgatc ccccagatct ttgggaaagg agaatgcgct cggcaagtgg    720

ccaatatgat gatcaggatg aagagagagt ttacaggaag ccagaattca atatttcctg    780

tttttgataa tctcttgttg cttgatcgga atgtggattt attaacacct cttgccactc    840

agctgacata tgaaggactc attgatgaaa tttatggcat tcagaacagt tatgtgaaat    900

tacctccaga gaaatttgca cctaagaaac agggcgatgg tggtaaggac ctccccacgg    960

aagcaaagaa gctgcagctg aattctgcag aggagctcta tgctgagatc cgagataaga   1020

acttcaacgc agttggctct gtgctcagca agaaagcaaa gatcatctct gcagcattcg   1080

aggaaagaca caatgctaag accgtggggg agatcaagca gtttgtttcc cagttgcccc   1140

acatgcaggc agcaaggggc tcgcttgcaa accatacctc aattgcagaa ttgatcaaag   1200

atgtcactac ttctgaagac ttttttgata aattaaccgt ggaacaggag tttatgtctg   1260

gaatagacac tgataaggtc aacaattaca ttgaggattg tatcgcccaa aagcactcgt   1320

tgatcaaggt gttaagacta gtttgcctcc aatccgtgtg taatagtggg ctcaaacaaa   1380

aagttttgga ttattacaaa agagagattc tccagacata cggctatgag cacatattga   1440

ccttacacaa cctggagaag gccggcctgc tgaaaccgca gacggggggc agaaacaatt   1500

acccaactat acggaaaaca ttacgcctct ggatggatga tgttaatgag caaaacccca   1560

cggacatatc gtatgtgtac agtgggtatg ccccgctcag tgtgcggctg gcccagctgc   1620

tttcccggcc tggctggcgg agcatcgagg aggtcctccg catcctccca gggccccact   1680

ttgaggagcg gcagccactg cccacaggac tgcagaagaa acgtcaaccg ggagaaaacc   1740

gagtgactct gatatttttc cttgggggcg taaccttcgc tgaaattgct gccctgcgat   1800

ttctctccca gttggaagat ggaggtacag aatatgtcat tgccaccact aaactaatga   1860

atggaaccag ttggatagag gctctgatgg aaaaaccttt ctaggatgtt cagaggagac   1920

ttaacaagtg tactgcagaa taaactacct ctttgaagaa attgctgaaa ggaagtaaaa   1980

ccccatagaa gaaacatggg aatacagaat atattctggg gtcagcttct taaattatac   2040

tactgtttac tgctt                                                    2055


<210>  8137
<211>  596
<212>  PRT
<213>  Homo sapiens

<400>  8137

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Glu Cys Tyr Leu Glu Gly Asp Gln Thr Ser Leu Tyr His Ala Ala 
                165                 170                 175


Lys Gly Leu Met Thr Leu Gln Ala Leu Tyr Gly Thr Ile Pro Gln Ile 
            180                 185                 190


Phe Gly Lys Gly Glu Cys Ala Arg Gln Val Ala Asn Met Met Ile Arg 
        195                 200                 205


Met Lys Arg Glu Phe Thr Gly Ser Gln Asn Ser Ile Phe Pro Val Phe 
    210                 215                 220


Asp Asn Leu Leu Leu Leu Asp Arg Asn Val Asp Leu Leu Thr Pro Leu 
225                 230                 235                 240


Ala Thr Gln Leu Thr Tyr Glu Gly Leu Ile Asp Glu Ile Tyr Gly Ile 
                245                 250                 255


Gln Asn Ser Tyr Val Lys Leu Pro Pro Glu Lys Phe Ala Pro Lys Lys 
            260                 265                 270


Gln Gly Asp Gly Gly Lys Asp Leu Pro Thr Glu Ala Lys Lys Leu Gln 
        275                 280                 285


Leu Asn Ser Ala Glu Glu Leu Tyr Ala Glu Ile Arg Asp Lys Asn Phe 
    290                 295                 300


Asn Ala Val Gly Ser Val Leu Ser Lys Lys Ala Lys Ile Ile Ser Ala 
305                 310                 315                 320


Ala Phe Glu Glu Arg His Asn Ala Lys Thr Val Gly Glu Ile Lys Gln 
                325                 330                 335


Phe Val Ser Gln Leu Pro His Met Gln Ala Ala Arg Gly Ser Leu Ala 
            340                 345                 350


Asn His Thr Ser Ile Ala Glu Leu Ile Lys Asp Val Thr Thr Ser Glu 
        355                 360                 365


Asp Phe Phe Asp Lys Leu Thr Val Glu Gln Glu Phe Met Ser Gly Ile 
    370                 375                 380


Asp Thr Asp Lys Val Asn Asn Tyr Ile Glu Asp Cys Ile Ala Gln Lys 
385                 390                 395                 400


His Ser Leu Ile Lys Val Leu Arg Leu Val Cys Leu Gln Ser Val Cys 
                405                 410                 415


Asn Ser Gly Leu Lys Gln Lys Val Leu Asp Tyr Tyr Lys Arg Glu Ile 
            420                 425                 430


Leu Gln Thr Tyr Gly Tyr Glu His Ile Leu Thr Leu His Asn Leu Glu 
        435                 440                 445


Lys Ala Gly Leu Leu Lys Pro Gln Thr Gly Gly Arg Asn Asn Tyr Pro 
    450                 455                 460


Thr Ile Arg Lys Thr Leu Arg Leu Trp Met Asp Asp Val Asn Glu Gln 
465                 470                 475                 480


Asn Pro Thr Asp Ile Ser Tyr Val Tyr Ser Gly Tyr Ala Pro Leu Ser 
                485                 490                 495


Val Arg Leu Ala Gln Leu Leu Ser Arg Pro Gly Trp Arg Ser Ile Glu 
            500                 505                 510


Glu Val Leu Arg Ile Leu Pro Gly Pro His Phe Glu Glu Arg Gln Pro 
        515                 520                 525


Leu Pro Thr Gly Leu Gln Lys Lys Arg Gln Pro Gly Glu Asn Arg Val 
    530                 535                 540


Thr Leu Ile Phe Phe Leu Gly Gly Val Thr Phe Ala Glu Ile Ala Ala 
545                 550                 555                 560


Leu Arg Phe Leu Ser Gln Leu Glu Asp Gly Gly Thr Glu Tyr Val Ile 
                565                 570                 575


Ala Thr Thr Lys Leu Met Asn Gly Thr Ser Trp Ile Glu Ala Leu Met 
            580                 585                 590


Glu Lys Pro Phe 
        595


<210>  8138
<211>  875
<212>  DNA
<213>  Homo sapiens

<400>  8138
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaagagt    600

gctacctgga gggtgaccag acgagcctgt accacgcagc caaggggctg atgaccctgc    660

aagctctgta tggaacgatc ccccagatct ttgggaaagg agaatgcgct cgggtgagaa    720

ccggctgctt tgtggtggta aaggagggcc cttcacaccc caaaagggag gaggaacggg    780

aagctcctta caaacaaatt cagttgatct taattattta tgaatactgt actcatgaat    840

ttgcctactg attaaaatgc acttataacc ctcca                               875


<210>  8139
<211>  245
<212>  PRT
<213>  Homo sapiens

<400>  8139

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Glu Cys Tyr Leu Glu Gly Asp Gln Thr Ser Leu Tyr His Ala Ala 
                165                 170                 175


Lys Gly Leu Met Thr Leu Gln Ala Leu Tyr Gly Thr Ile Pro Gln Ile 
            180                 185                 190


Phe Gly Lys Gly Glu Cys Ala Arg Val Arg Thr Gly Cys Phe Val Val 
        195                 200                 205


Val Lys Glu Gly Pro Ser His Pro Lys Arg Glu Glu Glu Arg Glu Ala 
    210                 215                 220


Pro Tyr Lys Gln Ile Gln Leu Ile Leu Ile Ile Tyr Glu Tyr Cys Thr 
225                 230                 235                 240


His Glu Phe Ala Tyr 
                245


<210>  8140
<211>  1277
<212>  DNA
<213>  Homo sapiens

<400>  8140
gtgcgctgcc gtaccggtca cgtggacgtt tggtcacgtg actgcgtccg tggtcctccc     60

gtaggaaccg gcggactcgg ttggcgttgt ggggcagggg gtggtggagc aagatggcgg    120

ctcatctgtc ctacggccga gtgaacctaa acgtgttgcg cgaggcggtg cgtcgcgagc    180

tgcgcgagtt cctggacaag tgcgcaggaa gcaaggcaat agtttgggat gaatacctaa    240

ctggaccctt tggcctgatt gcacagtatt cactattgaa ggaacatgaa gtggaaaaaa    300

tgttcacact taaaggaaat cgtttgccgg cagctgatgt gaagaatata attttttttg    360

tcagacccag gctagagttg atggatataa tcgctgaaaa cgtgctcagt gaagatagac    420

gaggcccaac gagagatttt catattctgt ttgtgccacg ccgtagcctg ttgtgcgaac    480

agcggttgaa ggatctgggt gtcttgggat cctttattca cagggaggag tacagcttag    540

atctcattcc attcgatggg gatctcttat ccatggaatc agagggtgca ttcaaatctt    600

gctctgttgc cccggctgga gtgcagtggc acaatctcag ctcactgcaa cctccacctc    660

ctgagttcaa gtgattctgc tgcctcagtc acctgagtag ctgggattac aggcacatgc    720

caccacacct ggctaatttt tgtattttta gtagagaagg ggtttcacca ttttggtcag    780

gctggtctag aactcccgac ctcatgatcc tccccgctca gcctcccaaa gtgctgggat    840

tacaggcgtg agccaccgca cccagccctc aatgtctttt gcccttgaac gttcatctga    900

tctggagttt taagtggttt tgccaaaaag cgtgtctttt gacatattct cgatggtctg    960

ccatattcag ggaaacgtta aaatatacca cacttgaaag agtagtccgg cgacactctc   1020

aataataacc aaacgctccc caccatgtct gccatccttc ctccctgggg cagagggcct   1080

gacaagtgac aaccccgctc tctcttcctc aggccctgga ccctcagggc cccctcagtt   1140

ctggctgtgg acagcaggga catgttgggt tggtaggggt ggagggaatt gataaaatgt   1200

accatattga cttatgagtg gataatggtt gtaaaaaaac ctaaataatt ccaaataaaa   1260

gctaactgtt actgagc                                                  1277


<210>  8141
<211>  186
<212>  PRT
<213>  Homo sapiens

<400>  8141

Met Ala Ala His Leu Ser Tyr Gly Arg Val Asn Leu Asn Val Leu Arg 
1               5                   10                  15


Glu Ala Val Arg Arg Glu Leu Arg Glu Phe Leu Asp Lys Cys Ala Gly 
            20                  25                  30


Ser Lys Ala Ile Val Trp Asp Glu Tyr Leu Thr Gly Pro Phe Gly Leu 
        35                  40                  45


Ile Ala Gln Tyr Ser Leu Leu Lys Glu His Glu Val Glu Lys Met Phe 
    50                  55                  60


Thr Leu Lys Gly Asn Arg Leu Pro Ala Ala Asp Val Lys Asn Ile Ile 
65                  70                  75                  80


Phe Phe Val Arg Pro Arg Leu Glu Leu Met Asp Ile Ile Ala Glu Asn 
                85                  90                  95


Val Leu Ser Glu Asp Arg Arg Gly Pro Thr Arg Asp Phe His Ile Leu 
            100                 105                 110


Phe Val Pro Arg Arg Ser Leu Leu Cys Glu Gln Arg Leu Lys Asp Leu 
        115                 120                 125


Gly Val Leu Gly Ser Phe Ile His Arg Glu Glu Tyr Ser Leu Asp Leu 
    130                 135                 140


Ile Pro Phe Asp Gly Asp Leu Leu Ser Met Glu Ser Glu Gly Ala Phe 
145                 150                 155                 160


Lys Ser Cys Ser Val Ala Pro Ala Gly Val Gln Trp His Asn Leu Ser 
                165                 170                 175


Ser Leu Gln Pro Pro Pro Pro Glu Phe Lys 
            180                 185


<210>  8142
<211>  672
<212>  DNA
<213>  Homo sapiens

<400>  8142
catgaaattc tctcctttaa ggtgcaaaat tcagtggttt ttagtgtatt tacaaagttg     60

tgcaactatc tccactctct aagtatggca cattttaact attccgaaaa gaatccccat    120

gcccagtagc agtctgtcgc tatctttcct tccctcagcc tctggcagcc actaatctag    180

ttcagtctgt atgaattcgc ttattctgga gttttccttt tcttcttttt ttgagataga    240

gtctcactct tttgcccagg ttggagtgca gtgacgtgat aatacctcac tgcagccttg    300

acctcctagg cttgaacgaa ttttcagcct cagcctccca gagtgctggg attacaggcg    360

tgggccattg cgcccaaccc tcttggctct tttgtacctt gttccctagt ggtttgctta    420

cacgaaatcc tacctgatgg taatatagat ttccttctaa cattttatag gaaaatttca    480

atataccaaa aaattgaatt gtacagtgaa cacctgtcta tccaccactt atcttctgga    540

ttaacagttt tctatatgtg ctttatcaca tacctgtgat ggtatactca tttttaatta    600

atccatattt gtgtatttaa tgggaattgg tagcagccga agcaaactct cttggagtga    660

caaaatctgt gc                                                        672


<210>  8143
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  8143

Ser Leu Thr Leu Leu Pro Arg Leu Glu Cys Ser Asp Val Ile Ile Pro 
1               5                   10                  15


His Cys Ser Leu Asp Leu Leu Gly Leu Asn Glu Phe Ser Ala Ser Ala 
            20                  25                  30


Ser Gln Ser Ala Gly Ile Thr Gly Val Gly His Cys Ala Gln Pro Ser 
        35                  40                  45


Trp Leu Phe Cys Thr Leu Phe Pro Ser Gly Leu Leu Thr Arg Asn Pro 
    50                  55                  60


Thr 
65


<210>  8144
<211>  2505
<212>  DNA
<213>  Homo sapiens

<400>  8144
taaataaata aaataattaa ttaattcatg gcctggcacc gtggctcaca catgtattcc     60

cagcactttg ggaggccaag ccgggtggat cacctgaggt caggagtttg agaccatcct    120

ggccaacatg gcaaaacccc gtctctacta aaaatacaaa aatcagccag gcatggtggt    180

gcatgcctgt aatcccagct attcaggagg ctgagacagt agaattgctt gaacccagga    240

gacagaggct gcagtgagcc gagatcctgc cactgcactc cagcctgggc gacagagcga    300

gactccgtct caaaaaaaaa aaaaaaacaa aacaaaacaa atgaagttta cccatgttat    360

acctagaaac attcaatgaa gtgtaattta aatttttttt taaaatataa aatagcatct    420

cctcagtaat gaacatttga agaaatctga aaggtgtgag ggggtaaaag aaactgccat    480

agccttacca cctagacatg gcctcattta agttcagctc tttactcaca caatctcagc    540

atgcctgtcc tccgggagag tgaaaagcat gggttcctaa tagccgctgt tggccccttc    600

tgcacacttt gccgccagag cttaaaggta taaacttcat gacttcttga tgctccagct    660

tatatatatt cttgacattt tacacatttt ttttttaaca aatcagattg atttcctaaa    720

ttcagtaata gtggaccttc aaaggaagaa tcaagacctc aagatgaagg tggagatgat    780

gtcagaagca gccctgaatg ggaacgggga tgacctaaac aattatgaca gtgatgatca    840

ggagaaacag tccaagaaga aacctcgcct cttctgtgac atttgtgact gctttgatct    900

ccacgacaca gaggattgtc ctacccaggc acagatgtca gaggaccctc cccattccac    960

acaccatggc agtcggggtg aggaacgccc atactgtgaa atctgtgaga tgtttggaca   1020

ctgggccacc aactgcaatg acgacgaaac cttctgatga agcctccagt ggagaactgg   1080

gcttgctcag acgcactcgc attgacacaa cgtaacacca gcattgtgtg tgcagacttc   1140

aggagaactc atgttatttt ttaaccccgt caacaaatct aggaaaatat tttgatcttc   1200

aacaaattgc cctttagtct ccccgtatga gttagaataa taaatattta gtaggtgagt   1260

tttcacctcg aattttgttt tcttgatttt tacgtttgaa gacattgcac cagatgccat   1320

tacatttatt ggccccccga ccttgtagaa aaacccctac cctcacaata ccttatttaa   1380

gtaactttaa attatgccgt tacttttcat atttgcacta agatatttcc aggctgcatt   1440

tgtatattta gattttttgg ttaagctttg acactggaat gagttgaaaa aatgtgccat   1500

tttgcatttt catctactca tttaaagtat tttattctta ttcaaagaaa tatctgagct   1560

ctttgcacta cctgttatca gtagtgcctt tacttcaggc ttgataatac ttaggtgtga   1620

ttataaaatc atgaagcagg taaagggagg ggcaagcccc caaactgctg tggggacatt   1680

ttataatcta tatgctgcac ccacttaatc tactgtggtg ttttgtttat tagttttgca   1740

taatttcagc ttctatatat tgtatgtata tattttttaa aaatctatat tttgggaaaa   1800

aaacatacac aatgtgtctt tctttttgga catttacctt tttgaaaaag aaaacactta   1860

aaatgatcat taggacataa cagactaggc cagacatagc atcttgtggc tttgcaacca   1920

ttttcatttg tttgttttcc ttttatttct tcaccagatt taaataactg gaggaatttt   1980

ctccaatttt tttttccttc tctggcaggt atccccagca gtcaattaac aataagccag   2040

tataaaacac ctaaataacc aatctacaat ctcccttcac aagttttttt actgttttta   2100

gatgaatgta cgatgagaaa ttcaacgtta ataattctgg attttcttat cacaaaaaag   2160

aaaatgaagg acctcaaagc acctgaacag tttatcgacc agtttgaatc tatttatctt   2220

catttgaatg tcttctagaa tatgtaaaaa gtcataaaat gtatcttcca tgctacatgt   2280

acaataagaa cttctataat tgtatatatg cctttgatgt attttcccct caagattatc   2340

aactgtgtgt tcgacagtga atattcaatc tggtaccagt tgaaattttt ggttataaat   2400

gtaatacgaa ttgtttcaca aacagaaaac atgtaaagca gtattaaaat ttggccaaac   2460

aagtgttctg tatctacttt aataaatggt tattcttttt tgttt                   2505


<210>  8145
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  8145

Met Leu Gln Leu Ile Tyr Ile Leu Asp Ile Leu His Ile Phe Phe Leu 
1               5                   10                  15


Thr Asn Gln Ile Asp Phe Leu Asn Ser Val Ile Val Asp Leu Gln Arg 
            20                  25                  30


Lys Asn Gln Asp Leu Lys Met Lys Val Glu Met Met Ser Glu Ala Ala 
        35                  40                  45


Leu Asn Gly Asn Gly Asp Asp Leu Asn Asn Tyr Asp Ser Asp Asp Gln 
    50                  55                  60


Glu Lys Gln Ser Lys Lys Lys Pro Arg Leu Phe Cys Asp Ile Cys Asp 
65                  70                  75                  80


Cys Phe Asp Leu His Asp Thr Glu Asp Cys Pro Thr Gln Ala Gln Met 
                85                  90                  95


Ser Glu Asp Pro Pro His Ser Thr His His Gly Ser Arg Gly Glu Glu 
            100                 105                 110


Arg Pro Tyr Cys Glu Ile Cys Glu Met Phe Gly His Trp Ala Thr Asn 
        115                 120                 125


Cys Asn Asp Asp Glu Thr Phe 
    130                 135


<210>  8146
<211>  1841
<212>  DNA
<213>  Homo sapiens

<400>  8146
ttcatctgct gctgacaaca cttttcttcc aatcagcaaa tgattgattt cctaaattca     60

gtaatagtgg accttcaaag gaagaatcaa gacctcaaga tgaaggtgga gatgatgtca    120

gaagcagccc tgaatgggaa cggggatgac ctaaacaatt atgacagtga tgatcaggag    180

aaacagtcca agaagaaacc tcgcctcttc tgtgacattt gtgactgctt tgatctccac    240

gacacagagg attgtcctac ccaggcacag atgtcagagg accctcccca ttccacacac    300

catggcagtc ggggtgagga acgcccatac tgtgaaatct gtgagatgtt tggacactgg    360

gccaccaact gcaatgacga cgaaaccttc tgatgaagcc tccagtggag aactgggctt    420

gctcagacgc actcgcattg acacaacgta acaccagcat tgtgtgtgca gacttcagga    480

gaactcatgt tattttttaa ccccgtcaac aaatctagga aaatattttg atcttcaaca    540

aattgccctt tagtctcccc gtatgagtta gaataataaa tatttagtag gtgagttttc    600

acctcgaatt ttgttttctt gatttttacg tttgaagaca ttgcaccaga tgccattaca    660

tttattggcc ccccgacctt gtagaaaaac ccctaccctc acaatacctt atttaagtaa    720

ctttaaatta tgccgttact tttcatattt gcactaagat atttccaggc tgcatttgta    780

tatttagatt ttttggttaa gctttgacac tggaatgagt tgaaaaaatg tgccattttg    840

cattttcatc tactcattta aagtatttta ttcttattca aagaaatatc tgagctcttt    900

gcactacctg ttatcagtag tgcctttact tcaggcttga taatacttag gtgtgattat    960

aaaatcatga agcaggtaaa gggaggggca agcccccaaa ctgctgtggg gacattttat   1020

aatctatatg ctgcacccac ttaatctact gtggtgtttt gtttattagt tttgcataat   1080

ttcagcttct atatattgta tgtatatatt ttttaaaaat ctatattttg ggaaaaaaac   1140

atacacaatg tgtctttctt tttggacatt tacctttttg aaaaagaaaa cacttaaaat   1200

gatcattagg acataacaga ctaggccaga catagcatct tgtggctttg caaccatttt   1260

catttgtttg ttttcctttt atttcttcac cagatttaaa taactggagg aattttctcc   1320

aatttttttt tccttctctg gcaggtatcc ccagcagtca attaacaata agccagtata   1380

aaacacctaa ataaccaatc tacaatctcc cttcacaagt ttttttactg tttttagatg   1440

aatgtacgat gagaaattca acgttaataa ttctggattt tcttatcaca aaaaagaaaa   1500

tgaaggacct caaagcacct gaacagttta tcgaccagtt tgaatctatt tatcttcatt   1560

tgaatgtctt ctagaatatg taaaaagtca taaaatgtat cttccatgct acatgtacaa   1620

taagaacttc tataattgta tatatgcctt tgatgtattt tcccctcaag attatcaact   1680

gtgtgttcga cagtgaatat tcaatctggt accagttgaa atttttggtt ataaatgtaa   1740

tacgaattgt ttcacaaaca gaaaacatgt aaagcagtat taaaatttgg ccaaacaagt   1800

gttctgtatc tactttaata aatggttatt cttttttgtt t                       1841


<210>  8147
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  8147

Met Ile Asp Phe Leu Asn Ser Val Ile Val Asp Leu Gln Arg Lys Asn 
1               5                   10                  15


Gln Asp Leu Lys Met Lys Val Glu Met Met Ser Glu Ala Ala Leu Asn 
            20                  25                  30


Gly Asn Gly Asp Asp Leu Asn Asn Tyr Asp Ser Asp Asp Gln Glu Lys 
        35                  40                  45


Gln Ser Lys Lys Lys Pro Arg Leu Phe Cys Asp Ile Cys Asp Cys Phe 
    50                  55                  60


Asp Leu His Asp Thr Glu Asp Cys Pro Thr Gln Ala Gln Met Ser Glu 
65                  70                  75                  80


Asp Pro Pro His Ser Thr His His Gly Ser Arg Gly Glu Glu Arg Pro 
                85                  90                  95


Tyr Cys Glu Ile Cys Glu Met Phe Gly His Trp Ala Thr Asn Cys Asn 
            100                 105                 110


Asp Asp Glu Thr Phe 
        115


<210>  8148
<211>  2464
<212>  DNA
<213>  Homo sapiens

<400>  8148
taaataaata aaataattaa ttaattcatg gcctggcacc gtggctcaca catgtattcc     60

cagcactttg ggaggccaag ccgggtggat cacctgaggt caggagtttg agaccatcct    120

ggccaacatg gcaaaacccc gtctctacta aaaatacaaa aatcagccag gcatggtggt    180

gcatgcctgt aatcccagct attcaggagg ctgagacagt agaattgctt gaacccagga    240

gacagaggct gcagtgagcc gagatcctgc cactgcactc cagcctgggc gacagagcga    300

gactccgtct caaaaaaaaa aaaaaaacaa aacaaaacaa atgaagttta cccatgttat    360

acctagaaac attcaatgaa gtgtaattta aatttttttt taaaatataa aatagcatct    420

cctcagtaat gaacatttga agaaatctga aaggtgtgag ggggtaaaag aaactgccat    480

agccttacca cctagacatg gcctcattta agttcagctc tttactcaca caatctcagc    540

atgcctgtcc tccgggagag tgaaaagcat gggttcctaa tagccgctgt tggccccttc    600

tgcacacttt gccgccagag cttaaaggta taaacttcat gacttcttga tgctccagct    660

tatatatatt cttgacattt tacacatttt ttttttaaca aatcagattg atttcctaaa    720

ttcagtaata gtggaccttc aaaggaagaa tcaagacctc aagatgaagg tggagatgat    780

gtcagaagca gccctgaatg ggaacgggga tgacctaaac aattatgaca gtgatgatca    840

ggagaaacag tccaagaaga aacctcgcct cttctgtgac atttgtgact gctttgatct    900

ccacgacaca gaggattgtc ctacccaggc acagatgtca gaggaccctc cccattccac    960

acaccatggc agtcggggtg aggaacgccc atactgtgaa atctgtgaga tgtttggaca   1020

ctgggccacc aactgcaatg acgacgaaac cttctgatga agcctccagt ggagaactgg   1080

gcttgctcag acgcactcgc attgacacaa cgtaacacca gcattgtgtg tgcagacttc   1140

aggagaactc atgttatttt ttaaccccgt caacaaatct aggaaaatat tttgatcttc   1200

aacaaattgc cctttagtct ccccgtatga gttagaataa taaatattta gtaggtgagt   1260

tttcacctcg aattttgttt tcttgatttt tacgtttgaa gacattgcac cagatgccat   1320

tacatttatt ggccccccga ccttgtagaa aaacccctac cctcacaata ccttatttaa   1380

gtaactttaa attatgccgt tacttttcat atttgcacta agatatttcc aggctgcatt   1440

tgtatattta gattttttgg ttaagctttg acactggaat gagttgaaaa aatgtgccat   1500

tttgcatttt catctactca tttaaagtat tttattctta ttcaaagaaa tatctgagct   1560

ctttgcacta cctgttatca gtagtgcctt tacttcaggc ttgataatac ttaggtgtga   1620

ttataaaatc atgaagcagg taaagggagg ggcaagcccc caaactgctg tggggacatt   1680

ttataatcta tatgctgcac ccacttaatc tactgtggtg ttttgtttat tagttttgca   1740

taatttcagc ttctatatat tgtatgtata tattttttaa aaatctatat tttgggaaaa   1800

aaacatacac aatgtgtctt tctttttgga catttacctt tttgaaaaag aaaacactta   1860

aaatgatcat taggacataa cagactaggc cagacatagc atcttgtggc tttgcaacca   1920

ttttcatttg tttgttttcc ttttatttct tcaccagatt taaataactg gaggaatttt   1980

ctccaatttt tttttccttc tctggcaggt atccccagca gtcaattaac aataagccag   2040

tataaaacac ctaaataacc aatctacaat ctcccttcac aagttttttt actgttttta   2100

gatgaatgta cgatgagaaa ttcaacgtta ataattctgg attttcttat cacaaaaaag   2160

aaaatgaagg acctcaaagc acctgaacag tttatcgacc agtttgaatc tatttatctt   2220

catttgaatg tcttctagaa tatgtaaaaa gtcataaaat gtatcttcca tgctacatgt   2280

acaataagaa cttctataat tgtatatatg cctttgatgt attttcccct caagattatc   2340

aactgtgtgt tcgacagtga atattcaatc tggtaccagt tgaaattttt ggttataaat   2400

gtaatacgaa ttgtttcaca aacagaaaac atgtaaagca gtattaaaat ttggccaaac   2460

aagt                                                                2464


<210>  8149
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  8149

Met Leu Gln Leu Ile Tyr Ile Leu Asp Ile Leu His Ile Phe Phe Leu 
1               5                   10                  15


Thr Asn Gln Ile Asp Phe Leu Asn Ser Val Ile Val Asp Leu Gln Arg 
            20                  25                  30


Lys Asn Gln Asp Leu Lys Met Lys Val Glu Met Met Ser Glu Ala Ala 
        35                  40                  45


Leu Asn Gly Asn Gly Asp Asp Leu Asn Asn Tyr Asp Ser Asp Asp Gln 
    50                  55                  60


Glu Lys Gln Ser Lys Lys Lys Pro Arg Leu Phe Cys Asp Ile Cys Asp 
65                  70                  75                  80


Cys Phe Asp Leu His Asp Thr Glu Asp Cys Pro Thr Gln Ala Gln Met 
                85                  90                  95


Ser Glu Asp Pro Pro His Ser Thr His His Gly Ser Arg Gly Glu Glu 
            100                 105                 110


Arg Pro Tyr Cys Glu Ile Cys Glu Met Phe Gly His Trp Ala Thr Asn 
        115                 120                 125


Cys Asn Asp Asp Glu Thr Phe 
    130                 135


<210>  8150
<211>  1800
<212>  DNA
<213>  Homo sapiens

<400>  8150
ttcatctgct gctgacaaca cttttcttcc aatcagcaaa tgattgattt cctaaattca     60

gtaatagtgg accttcaaag gaagaatcaa gacctcaaga tgaaggtgga gatgatgtca    120

gaagcagccc tgaatgggaa cggggatgac ctaaacaatt atgacagtga tgatcaggag    180

aaacagtcca agaagaaacc tcgcctcttc tgtgacattt gtgactgctt tgatctccac    240

gacacagagg attgtcctac ccaggcacag atgtcagagg accctcccca ttccacacac    300

catggcagtc ggggtgagga acgcccatac tgtgaaatct gtgagatgtt tggacactgg    360

gccaccaact gcaatgacga cgaaaccttc tgatgaagcc tccagtggag aactgggctt    420

gctcagacgc actcgcattg acacaacgta acaccagcat tgtgtgtgca gacttcagga    480

gaactcatgt tattttttaa ccccgtcaac aaatctagga aaatattttg atcttcaaca    540

aattgccctt tagtctcccc gtatgagtta gaataataaa tatttagtag gtgagttttc    600

acctcgaatt ttgttttctt gatttttacg tttgaagaca ttgcaccaga tgccattaca    660

tttattggcc ccccgacctt gtagaaaaac ccctaccctc acaatacctt atttaagtaa    720

ctttaaatta tgccgttact tttcatattt gcactaagat atttccaggc tgcatttgta    780

tatttagatt ttttggttaa gctttgacac tggaatgagt tgaaaaaatg tgccattttg    840

cattttcatc tactcattta aagtatttta ttcttattca aagaaatatc tgagctcttt    900

gcactacctg ttatcagtag tgcctttact tcaggcttga taatacttag gtgtgattat    960

aaaatcatga agcaggtaaa gggaggggca agcccccaaa ctgctgtggg gacattttat   1020

aatctatatg ctgcacccac ttaatctact gtggtgtttt gtttattagt tttgcataat   1080

ttcagcttct atatattgta tgtatatatt ttttaaaaat ctatattttg ggaaaaaaac   1140

atacacaatg tgtctttctt tttggacatt tacctttttg aaaaagaaaa cacttaaaat   1200

gatcattagg acataacaga ctaggccaga catagcatct tgtggctttg caaccatttt   1260

catttgtttg ttttcctttt atttcttcac cagatttaaa taactggagg aattttctcc   1320

aatttttttt tccttctctg gcaggtatcc ccagcagtca attaacaata agccagtata   1380

aaacacctaa ataaccaatc tacaatctcc cttcacaagt ttttttactg tttttagatg   1440

aatgtacgat gagaaattca acgttaataa ttctggattt tcttatcaca aaaaagaaaa   1500

tgaaggacct caaagcacct gaacagttta tcgaccagtt tgaatctatt tatcttcatt   1560

tgaatgtctt ctagaatatg taaaaagtca taaaatgtat cttccatgct acatgtacaa   1620

taagaacttc tataattgta tatatgcctt tgatgtattt tcccctcaag attatcaact   1680

gtgtgttcga cagtgaatat tcaatctggt accagttgaa atttttggtt ataaatgtaa   1740

tacgaattgt ttcacaaaca gaaaacatgt aaagcagtat taaaatttgg ccaaacaagt   1800


<210>  8151
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  8151

Met Ile Asp Phe Leu Asn Ser Val Ile Val Asp Leu Gln Arg Lys Asn 
1               5                   10                  15


Gln Asp Leu Lys Met Lys Val Glu Met Met Ser Glu Ala Ala Leu Asn 
            20                  25                  30


Gly Asn Gly Asp Asp Leu Asn Asn Tyr Asp Ser Asp Asp Gln Glu Lys 
        35                  40                  45


Gln Ser Lys Lys Lys Pro Arg Leu Phe Cys Asp Ile Cys Asp Cys Phe 
    50                  55                  60


Asp Leu His Asp Thr Glu Asp Cys Pro Thr Gln Ala Gln Met Ser Glu 
65                  70                  75                  80


Asp Pro Pro His Ser Thr His His Gly Ser Arg Gly Glu Glu Arg Pro 
                85                  90                  95


Tyr Cys Glu Ile Cys Glu Met Phe Gly His Trp Ala Thr Asn Cys Asn 
            100                 105                 110


Asp Asp Glu Thr Phe 
        115


<210>  8152
<211>  3004
<212>  DNA
<213>  Homo sapiens

<400>  8152
taggtacaca tatgtaaaca catgctagcc tgctctttgg gctgttttca ctgtgtcctg     60

cgttcctccc tgttcctcct tcgtctttcc ctttctcttc tcactcccac aaccctctca    120

ttaaaggcct catccccgcc ctctgctgat aaccaagtgc tgagtcaggc cgagaacata    180

aaccaggcgc tctgaatttc tccttccagg ctccccatgc tttcattctg cacctgagaa    240

aaccatttta acattttctg ttctagcctt tatgtaatta ccattaattt ctatgagcta    300

atttaatgtc ctcttcagag tctatggctg gaaagtaata atccttcagt ttgagtaata    360

ataataatct ttactactgt tttggcccat aacatcttaa acacccattc ttggaacttg    420

ctacaaaagt tactgaaatt agtgagaacc aattgatatt tccagcataa agctgctctg    480

catgacatct gtataactgc tttgcatgtg tgtattttaa ttgtcgttat tgcttggtaa    540

taatttattc aagaattaac aaacttcaac ttggggttag attttagtag aatattgggg    600

agggtgcaac cgtttttttt ttttttaatt ctacctcttc caaatttatt aacttgtttc    660

tttaagttca aatggataca atcacatgca gactctggca tgtctatgca taggtaaact    720

ttttctcccc tcacagtaag taaaatttca agtaaaattt tgtgagcata atggccttaa    780

ctccctataa aacttccctg ttatattttt ttttttacat taactaacat taattatgtg    840

tttgttctag aacagttgta cactgaccag tctttcggtt gatttgtgga acttttaact    900

ctttggtctt ttagagaatc caagttcata aaagacgcag atgaagagaa agcttccttg    960

cagaaatcca tcagtataac tagtgcctta ctcacagaaa aggatgccga gctggagaaa   1020

ctgagaaatg aggtcacagt gctcagggga gaaaacgcct ctgccaagtc cttgcattca   1080

gttgttcaga ctctagagtc tgataaggtg aagctcgagc tcaaggtaaa gaacttggag   1140

cttcaactca aagaaaacaa gaggcagctc agcagctcct caggtaatac agacactcag   1200

gcagacgagg atgaaagagc ccaggagagt caggtaatgt tcctgcctta ttgctttact   1260

ttcttgctgt ttttcaaaat cattgaatct tttcgtttat tttccttctc atttgatgcc   1320

ttttgtatca tttagtcttt tgaattggta atgcattcct ctagtccaaa cattaaacag   1380

aattaaaaat atatacatta aatgtcttcc tccaaacctt ctctctcttc tgctcagttc   1440

ccaaccctgc aaacagttaa ttactgttat ttgtgtcttt ccttttcaga gattttttaa   1500

agtgtgtata caagccagca ctaatacagt cttccctccc tttttttttt ttaacataaa   1560

taatggcata ctacataaac ggttctgcac ttattttttt tatagctatg tagtgttcca   1620

ttacgtggat ttactataat ttagtcagtt ccctattggt tgacaatgac actgggatgt   1680

ttctgatcct ttgggtgtat tataaacaat gccgtaagga attatcttgg gcagctatca   1740

ttttatatat tagtatttct gcaggatgaa ttcctagaag tagaattgct ctgtcaaagg   1800

gtttgttact catctgaacc ttaaaaagac tggtttcttg aaaactcagt ctcttaaagc   1860

gaaaattaac aaaacaactt tagttttaaa ctaaaaatgg gattaggcca ggaatggtgg   1920

cttatccctg taattccagc actttgggag gccaaggtgg gatgattgct tgagcccaaa   1980

agtttgagac caacctggac atagcgagac ctcatctcta caaaaaaaaa aaaacaaaaa   2040

aaacaaaaaa caatcctgca gcctgagtga cagagcaaca ccctgtctca aaacaattac   2100

ttaattaaaa aaaagttttt aagggcctgg gccaggtgca gtggctcacg cctataattc   2160

cagctttttg gaaggctgtg gcaagcggac tgtttgagat caggagatcg agaccagcct   2220

gagcaacaat ggcaagaccc catctctaca aaaaataaaa ttagttaggc atggcgccat   2280

gctcccatag tcccagttac cccagaagct gaggcaggag gatcacttga gtccagaagg   2340

ttgaggctgc agtgagccat gatcatgcca ccgcacttag gcctgactga caaagcaaga   2400

acctgtctca gaaaaaaaaa aggtggggtg gggggcccgg gcacagcagc tcacacctgc   2460

aatcccagca ctttggtagg ccaaggtagg cagatcgctg gagcccgaga ccagcctgcg   2520

caacatgggc actccaagct gggtgacaga gcaaggccct gtctcaaaac aaacaaaaat   2580

ttgtaaaaag ggattatata aaggcaaact attctgtact tggaaatata attgtatata   2640

gcaacaaaca tctgtctttt aattttaata tactttgtat gtattagtca tgttcaaaat   2700

tcaaaagtac aaaagccaca ttttatattt aaataaaaga aaaactcacc ttgagatgtt   2760

agttgccaga cacctccttt gaggggcaca aaacgattca acactgtaca aacttaccat   2820

ggattagcat tgtcctcttt gtatgtctac tgggcttaat aactaacagt gtcttctctt   2880

cccccttcct ttctgcttcg gtttgtttca tctgctgctg acaacacttt tcttccaatc   2940

agcaaatggt tcgtttcatg tttcctaatt tgcgtgcaca cgtgtgtgtg tgtgtgtgtg   3000

tgtg                                                                3004


<210>  8153
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  8153

Met Ile Met Pro Pro His Leu Gly Leu Thr Asp Lys Ala Arg Thr Cys 
1               5                   10                  15


Leu Arg Lys Lys Lys Gly Gly Val Gly Gly Pro Gly Thr Ala Ala His 
            20                  25                  30


Thr Cys Asn Pro Ser Thr Leu Val Gly Gln Gly Arg Gln Ile Ala Gly 
        35                  40                  45


Ala Arg Asp Gln Pro Ala Gln His Gly His Ser Lys Leu Gly Asp Arg 
    50                  55                  60


Ala Arg Pro Cys Leu Lys Thr Asn Lys Asn Leu 
65                  70                  75


<210>  8154
<211>  1545
<212>  DNA
<213>  Homo sapiens

<400>  8154
aatttcttaa ttttttggtg gagatgaggt ctcgtcatgt tgctcaggcc gctcttaaac     60

tcctggcttt aagccattct cccaccttgc cctcccaaag tgcaaagatg catttttaaa    120

cttgctatgt ctctaaggca tttctggtgg ctgtctgctt gaattcacca gggtagtgat    180

gatagatttt tttttttttt tttaaatata aggactgggt ctcactatgt tgccccagct    240

ggtctcaaac tcctggcctc aagcgatcct cctgcctcca cctcccaaat tgctgggatt    300

ataggagtgg cctaccatgc ccaacgtgtt tttttgtttg tttgttttgt ttttttaaag    360

gctgtgtgtt acttagtttc ttaagtgttt tgtttgggtt ttattccaca ggaaggttga    420

ggaccttcag ttccgggttg aagaagaatc aattaccaaa ggtgatcttg agcaaaagag    480

ccagatttct gaagatcctg agaatacgca gaccaaactg gagcatgccc gcattaagga    540

gcttgaacag agcctgctct ttgaaaagac caaagctgac aaactccaga gggagttaga    600

agacactagg gtggctacag tttcagaaaa gtcacgtata atggaactgg agaaagacct    660

agcattgaga gtacaggaag tagctgagct ccgaagaagg ctagagtcca ataagcctgc    720

tggggatgtg gacatgtcac tttccctttt gcaagagata agctctttgc aagaaaagtt    780

agaagtcacc cgtactgacc accagagaga aataacttct ctgaaggagc attttggagc    840

ccgggaagaa actcatcaga aggagataaa ggctctgtat accgccacgg aaaagctttc    900

caaagagaac gagtcattga aaagcaagct ggagcatgcc aacaaagaga actcagatgt    960

gatagctcta tggaagtcca aactggagac tgccatcgca tcccaccagc aggcgatgga   1020

agaactgaag gtatctttca gcaaagggct tggaacagag acggcagaat ttgctgaact   1080

aaaaacacaa atagagaaaa tgagactaga ttaccaacac gaaatagaaa atttgcagaa   1140

tcaacaagac tctgaacggg ctgcccatgc taaagagatg gaagccttga gggctaaact   1200

gatgaaagtt attaaagaaa aggaaaacag tctggaagcc atcaggtcga aactggacaa   1260

agcagaagac cagcatctcg tagaaatgga agacacgtta aacaaattac aggaagctga   1320

aataaaggta aaggagctag aggtactgca agccaaatgc aatgaacaaa ccaaggttat   1380

tgataatttt acatcacagc tcaaggctac tgaagaaaag ctcttggatc ttgatgcact   1440

tcggaaagcc agttccgaag gtaaatcgga aatgaagaaa cttagacagc agcttgaggc   1500

agctgagaaa cagattaaac atttagagat tgaaaagaat gctga                   1545


<210>  8155
<211>  300
<212>  PRT
<213>  Homo sapiens

<400>  8155

Met Glu Leu Glu Lys Asp Leu Ala Leu Arg Val Gln Glu Val Ala Glu 
1               5                   10                  15


Leu Arg Arg Arg Leu Glu Ser Asn Lys Pro Ala Gly Asp Val Asp Met 
            20                  25                  30


Ser Leu Ser Leu Leu Gln Glu Ile Ser Ser Leu Gln Glu Lys Leu Glu 
        35                  40                  45


Val Thr Arg Thr Asp His Gln Arg Glu Ile Thr Ser Leu Lys Glu His 
    50                  55                  60


Phe Gly Ala Arg Glu Glu Thr His Gln Lys Glu Ile Lys Ala Leu Tyr 
65                  70                  75                  80


Thr Ala Thr Glu Lys Leu Ser Lys Glu Asn Glu Ser Leu Lys Ser Lys 
                85                  90                  95


Leu Glu His Ala Asn Lys Glu Asn Ser Asp Val Ile Ala Leu Trp Lys 
            100                 105                 110


Ser Lys Leu Glu Thr Ala Ile Ala Ser His Gln Gln Ala Met Glu Glu 
        115                 120                 125


Leu Lys Val Ser Phe Ser Lys Gly Leu Gly Thr Glu Thr Ala Glu Phe 
    130                 135                 140


Ala Glu Leu Lys Thr Gln Ile Glu Lys Met Arg Leu Asp Tyr Gln His 
145                 150                 155                 160


Glu Ile Glu Asn Leu Gln Asn Gln Gln Asp Ser Glu Arg Ala Ala His 
                165                 170                 175


Ala Lys Glu Met Glu Ala Leu Arg Ala Lys Leu Met Lys Val Ile Lys 
            180                 185                 190


Glu Lys Glu Asn Ser Leu Glu Ala Ile Arg Ser Lys Leu Asp Lys Ala 
        195                 200                 205


Glu Asp Gln His Leu Val Glu Met Glu Asp Thr Leu Asn Lys Leu Gln 
    210                 215                 220


Glu Ala Glu Ile Lys Val Lys Glu Leu Glu Val Leu Gln Ala Lys Cys 
225                 230                 235                 240


Asn Glu Gln Thr Lys Val Ile Asp Asn Phe Thr Ser Gln Leu Lys Ala 
                245                 250                 255


Thr Glu Glu Lys Leu Leu Asp Leu Asp Ala Leu Arg Lys Ala Ser Ser 
            260                 265                 270


Glu Gly Lys Ser Glu Met Lys Lys Leu Arg Gln Gln Leu Glu Ala Ala 
        275                 280                 285


Glu Lys Gln Ile Lys His Leu Glu Ile Glu Lys Asn 
    290                 295                 300


<210>  8156
<211>  1207
<212>  DNA
<213>  Homo sapiens

<400>  8156
ctgacacttc atctggcctc atgtgttttc cattttttct ttctgaacag actagcccat     60

gccccctgcc caccaccatc ctttgtccct ggtattcatc ctcactgccc acctcatctc    120

acctccacct cttcccttct ccattcccct ttggttcacc ctttggcaga aggtactggt    180

ggctcagcct gcatgccgct gtctctcctc tcgtgctggc atgtcatggt ggcactgttg    240

tgttctcttc ctcttccttt ttactaacag acgcagacca aactggagca tgcccgcatt    300

aaggagcttg aacagagcct gctctttgaa aagaccaaag ctgacaaact ccagagggag    360

ttagaagaca ctagggtaat ggttttcact atttaatgaa gcagacccat gcatgtgaag    420

ggtggacacc tcaggtgaca tgctttatag ttggcctgag ccttgaccca gtggttcaac    480

ctgagtttgg tcttggtacc attcaggtgt ttgtgagctg agactgatga gtaggaacag    540

gtgttttata tctcgtcttt tgtcaaaagt aaagactcat tcctttggta acccaaccaa    600

atcaggatca gaaactttac aactgaataa atgaatggat ataactgtat ttgaagttat    660

ttatattaat accatgaaat atatttctcc agttggccac aagcagtcaa ttgtcctctt    720

gttctcaaat atctagttac taggctttct aaataatttt ttgttattgt tgttttactt    780

tagctctctt cctgccttct tccctggcct cttggagaag gaaatggaaa catgggctgt    840

gtttcatgag agttaaaaac tttcacccca gttacctttt tatcttggaa ggctgatctc    900

tgcatctccc tccttcctgt cgctcggggg attgaaacct cagtggacac tgggcgcagt    960

ggctcttgct tcttatccca gcactttggg aggctgaggc aggcagatta cttgaggtca   1020

ggagtttgag accagcctgg ccaacatgga gaaaccccat ctctactaaa aatactaaaa   1080

ttatccgggc gtggtgacac atgcctgtaa tcccagctac tagggaggct gaggcaggag   1140

aatcacttga acctgggagg cagaggttgc ggtgagccga gatcacgcca ttgcactcca   1200

gcctggg                                                             1207


<210>  8157
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  8157

Met Pro Pro Ala His His His Pro Leu Ser Leu Val Phe Ile Leu Thr 
1               5                   10                  15


Ala His Leu Ile Ser Pro Pro Pro Leu Pro Phe Ser Ile Pro Leu Trp 
            20                  25                  30


Phe Thr Leu Trp Gln Lys Val Leu Val Ala Gln Pro Ala Cys Arg Cys 
        35                  40                  45


Leu Ser Ser Arg Ala Gly Met Ser Trp Trp His Cys Cys Val Leu Phe 
    50                  55                  60


Leu Phe Leu Phe Thr Asn Arg Arg Arg Pro Asn Trp Ser Met Pro Ala 
65                  70                  75                  80


Leu Arg Ser Leu Asn Arg Ala Cys Ser Leu Lys Arg Pro Lys Leu Thr 
                85                  90                  95


Asn Ser Arg Gly Ser 
            100


<210>  8158
<211>  1465
<212>  DNA
<213>  Homo sapiens

<400>  8158
aggctgttca aaatgtttgc ccagcttctg gcaggatatg agctgatgcc tgccccgatt     60

ctacagacac catgagattt aatccagaga ctgacttcac tatagaaccc acagttgtat    120

caatggttgg ggaaagatag tggcaacagg caaaggagaa acagctctga catacaaaga    180

aaatgagtat gctaaagcca agtgggctta aggcccccac caagatcctg aagcctggaa    240

gcacagctct gaagacacct acggctgttg tagctccagt agaaaaaacc atatccagtg    300

aaaaagcatc aagcactcca tcatctgaga ctcaggagga atttgtggat gactttcgag    360

ttggggagcg agtttgggtg aatggaaata agcctggatt tatccagttt cttggagaaa    420

cccagtttgc accaggccag tgggctggaa ttgttttaga tgaacccata ggcaagaacg    480

atggttcggt ggcaggagtt cggtatttcc agtgtgaacc tttaaagggc atatttaccc    540

gaccttcaaa gttaacaagg aaggtgcaag cagaagatga agctaatggc ctgcagacaa    600

cgcccgcctc ccgagctact tcaccgctgt gcacttctac ggccagcatg gtgtcttcct    660

ccccctccac cccttcaaac atccctcaga aaccatcaca gccagcagca aaggaacctt    720

cagctacgcc tccgatcagc aaccttacaa aaactgccag tgaatctatc tccaaccttt    780

cagaggctgg ctcaatcaag aaaggagaaa gagagctcaa aatcggagac agagtattgg    840

ttggtggcac taaggctggt gtagtccggt ttcttgggga gaccgacttt gccaaggggg    900

agtggtgtgg cgtggagtta gatgagccac ttgggaagaa tgatggcgct gttgctggaa    960

caaggtattt tcagtgtcaa cccaaatatg gcttgttcgc tcctgtccac aaagttacca   1020

agattggctt cccttccact acaccagcca aagccaaggc caacgcagtg aggcgagtga   1080

tggcgaccac gtccgccagc ctgaagcgca gcccttctgc ctcttccctc agctccatga   1140

gctcagtggc ctcctctgtg agcagcaggc ccagtcggac aggactacat gtcctggaat   1200

tggaagccaa aatggaccag ctgcgaacaa tggtggaagc tgctgacagg gagaaggtgg   1260

agcttctcaa ccagcttgaa gaggagaaaa ggaaggttga ggaccttcag ttccgggttg   1320

aagaagaatc aattaccaaa ggtgatcttg agcaaaagag ccagatttct gaagatcctg   1380

agaatgtaag agggcactta actgtgtgga tatttccctt gttaacaaag attgatcaca   1440

gattaaaatg cttattgata tactc                                         1465


<210>  8159
<211>  426
<212>  PRT
<213>  Homo sapiens

<400>  8159

Met Ser Met Leu Lys Pro Ser Gly Leu Lys Ala Pro Thr Lys Ile Leu 
1               5                   10                  15


Lys Pro Gly Ser Thr Ala Leu Lys Thr Pro Thr Ala Val Val Ala Pro 
            20                  25                  30


Val Glu Lys Thr Ile Ser Ser Glu Lys Ala Ser Ser Thr Pro Ser Ser 
        35                  40                  45


Glu Thr Gln Glu Glu Phe Val Asp Asp Phe Arg Val Gly Glu Arg Val 
    50                  55                  60


Trp Val Asn Gly Asn Lys Pro Gly Phe Ile Gln Phe Leu Gly Glu Thr 
65                  70                  75                  80


Gln Phe Ala Pro Gly Gln Trp Ala Gly Ile Val Leu Asp Glu Pro Ile 
                85                  90                  95


Gly Lys Asn Asp Gly Ser Val Ala Gly Val Arg Tyr Phe Gln Cys Glu 
            100                 105                 110


Pro Leu Lys Gly Ile Phe Thr Arg Pro Ser Lys Leu Thr Arg Lys Val 
        115                 120                 125


Gln Ala Glu Asp Glu Ala Asn Gly Leu Gln Thr Thr Pro Ala Ser Arg 
    130                 135                 140


Ala Thr Ser Pro Leu Cys Thr Ser Thr Ala Ser Met Val Ser Ser Ser 
145                 150                 155                 160


Pro Ser Thr Pro Ser Asn Ile Pro Gln Lys Pro Ser Gln Pro Ala Ala 
                165                 170                 175


Lys Glu Pro Ser Ala Thr Pro Pro Ile Ser Asn Leu Thr Lys Thr Ala 
            180                 185                 190


Ser Glu Ser Ile Ser Asn Leu Ser Glu Ala Gly Ser Ile Lys Lys Gly 
        195                 200                 205


Glu Arg Glu Leu Lys Ile Gly Asp Arg Val Leu Val Gly Gly Thr Lys 
    210                 215                 220


Ala Gly Val Val Arg Phe Leu Gly Glu Thr Asp Phe Ala Lys Gly Glu 
225                 230                 235                 240


Trp Cys Gly Val Glu Leu Asp Glu Pro Leu Gly Lys Asn Asp Gly Ala 
                245                 250                 255


Val Ala Gly Thr Arg Tyr Phe Gln Cys Gln Pro Lys Tyr Gly Leu Phe 
            260                 265                 270


Ala Pro Val His Lys Val Thr Lys Ile Gly Phe Pro Ser Thr Thr Pro 
        275                 280                 285


Ala Lys Ala Lys Ala Asn Ala Val Arg Arg Val Met Ala Thr Thr Ser 
    290                 295                 300


Ala Ser Leu Lys Arg Ser Pro Ser Ala Ser Ser Leu Ser Ser Met Ser 
305                 310                 315                 320


Ser Val Ala Ser Ser Val Ser Ser Arg Pro Ser Arg Thr Gly Leu His 
                325                 330                 335


Val Leu Glu Leu Glu Ala Lys Met Asp Gln Leu Arg Thr Met Val Glu 
            340                 345                 350


Ala Ala Asp Arg Glu Lys Val Glu Leu Leu Asn Gln Leu Glu Glu Glu 
        355                 360                 365


Lys Arg Lys Val Glu Asp Leu Gln Phe Arg Val Glu Glu Glu Ser Ile 
    370                 375                 380


Thr Lys Gly Asp Leu Glu Gln Lys Ser Gln Ile Ser Glu Asp Pro Glu 
385                 390                 395                 400


Asn Val Arg Gly His Leu Thr Val Trp Ile Phe Pro Leu Leu Thr Lys 
                405                 410                 415


Ile Asp His Arg Leu Lys Cys Leu Leu Ile 
            420                 425


<210>  8160
<211>  478
<212>  DNA
<213>  Homo sapiens

<400>  8160
gtttctcctt tgcctgttgc cactatcttt ccccaaccat tgatacaact gtgggttcta     60

tagtgaagtc agtctctgga ttaaatctgc aaagagaaag aaataaaaag attttataat    120

ctacaggagc aagtaggaac aacaggtagc tttcatagac taaagctttc ctttcatttg    180

acaataatcc atctccaggc tgaacctagg aacctagaag actctggtta ttaaacacat    240

gaaaatgctg ctgaaatgga tttaaaggca atttactatc ctcaagacaa gcagttagcc    300

aggtgccatg acccactcct cacatctgta atcccagcac tttgggaggc taagatagga    360

ggactgtttg aggctgaggg ggaaggattt catgagccca ggagtttgag gctgcagtga    420

gccatgatcg atcacaccac tgtactccag cctgggtgac agagcaagac cccaactc      478


<210>  8161
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  8161

Met Asp Leu Lys Ala Ile Tyr Tyr Pro Gln Asp Lys Gln Leu Ala Arg 
1               5                   10                  15


Cys His Asp Pro Leu Leu Thr Ser Val Ile Pro Ala Leu Trp Glu Ala 
            20                  25                  30


Lys Ile Gly Gly Leu Phe Glu Ala Glu Gly Glu Gly Phe His Glu Pro 
        35                  40                  45


Arg Ser Leu Arg Leu Gln 
    50


<210>  8162
<211>  833
<212>  DNA
<213>  Homo sapiens

<400>  8162
ctgagattag cagcatctaa tctcagtttt ctccactgct gaccagcatc agcaacacag     60

gcagaaaaaa aattcttttg agccacagta aaacggcttc aaccgaaaga gtgaagaaac    120

agactctact gagctgcttt ctccacagaa acaagagtgc agtacagcca agccaggatg    180

gaattctagt cctgttttgg gtatcaaatc caaatcctgt aagcaaaagg tcaaggattc    240

agaagtgaaa ggaaagactg tggctctaac tttgccaaag tgaaaagtac agacctctgc    300

catcagtgaa gaaagaaccc agatctgata agagcttcaa acaggctcag cacctcctgg    360

cacacataga gcggcatcac gttgccccaa gaaaatcaca tctctacaca tcagaccctt    420

tccagtccat tttgccccat ccacaaaatg aaaatgccac tttatttact aaatctaaaa    480

attctgttgg gaggcaaagg agagttgaag aatttgcaat gaatttaacc tgccaggaga    540

gggagtttaa caccaagctt ccagaaacag gctgcgtggt agctacaacg tccagaaacc    600

caggtttcaa cgcggccctg cttcaagacc caaaggaaat tcagcaccag gcgggtgaag    660

tgacttacct gtgcacagct gcactcgcag acttcggagc ccccacctaa ttctaaaatg    720

ctgtatgtcc atgaacttaa taacagaagg tcaggggaga gacgttctga gagcaacgga    780

aatctatctt aagataaaga tgtttctgag gctgattttt caagtcaaac ttg           833


<210>  8163
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8163

Met Asn Leu Thr Cys Gln Glu Arg Glu Phe Asn Thr Lys Leu Pro Glu 
1               5                   10                  15


Thr Gly Cys Val Val Ala Thr Thr Ser Arg Asn Pro Gly Phe Asn Ala 
            20                  25                  30


Ala Leu Leu Gln Asp Pro Lys Glu Ile Gln His Gln Ala Gly Glu Val 
        35                  40                  45


Thr Tyr Leu Cys Thr Ala Ala Leu Ala Asp Phe Gly Ala Pro Thr 
    50                  55                  60


<210>  8164
<211>  1832
<212>  DNA
<213>  Homo sapiens

<400>  8164
gaaccttttt tggccaagtg attgtgtcag gtagtctttt agtattcagt cttaattatt     60

ttgcaggcaa gtttagtttt ccttcaacac attattttcc ttaatttcca ataaaggaaa    120

agtaacataa gaaggaaaaa tgtaatttga gatctccact gtacctcctt tgagcaaaat    180

ctcaaaacat gacattttcc aaatacatgt gttttttttt tccttctctt ttcatcatta    240

ggaatggagg atctttggtt ccataccaat gcaggcatgt cagcagaagg atgtgtttgc    300

caattacctt acttctaact tccaagcgcc aggtgtgaag tctggcaaca agaggtcttc    360

atctcactct agcccaggta gtccaaagaa gcagaagaat gaaagcaact cagcgggatc    420

tcccgccgac atggagctcg attcagatat ggaggtacca catggttctc agagcagcga    480

aagttttcag tttcaaccac cattacctcc tgacactcct ccactccccc ggggaactcc    540

tccacccgtc ttcacccctc cactcccaaa gggcaccccg ccgctgactc ccagtgactc    600

accccagacc agaacagcat ctggagctgt ggatgaggac gcactgactc tagaagaact    660

tgaagaacag cagaggcgga tctgggcagc tcttgagcag gccgagagcg taaacagcga    720

ctccgacgtt cctgtggaca cacctttaac tggcaattcc gttgcctcat caccttgtcc    780

aaatgagcta gacctccctg tcccggaggg aaaaacatct gaaaagcaga cgctggatga    840

gcctgaggta ccagagattt ttacaaagaa atcagaagct ggacatgcct ccagtccaga    900

ctctgaggtg acatcacttt gtcagaagga aaaagcagag ttggctccgg taaacactga    960

aggtgccctt cttgataatg gcagtgtcgt accaaactgt gacatcagca atgggggcag   1020

ccagaagctc tttcctgcag acaccagtcc ttcaacggcc actaaaattc atagccctat   1080

acctgacatg agcaaatttg caactggaat cacgccattt gaatttgaga atatggcaga   1140

atctactgga atgtacctca ggataagaag cttgttaaag aactcacccc gaaaccagca   1200

gaaaaacaaa aaggcctctg aataatggct tgacttagca ctgagagcta tttaataact   1260

ttgttccgtt aattagtact aattaagtgg atagatagaa tggttttcct gtttgtccct   1320

cccatgttta aaaatctatc caaggttcat gttccaaagt caagcctatt ttaaagaaag   1380

actgagctca ctagttcagt atattttatt ctcactgaca aaacttgggg ggagatgtga   1440

atatgacctg gtttagagag ggtttgttaa ggtttatact atttttggat tgtgactatc   1500

cgtcgagagt gatggttttt atctgtcttt tgtacattgt tttccctttc tacattttgc   1560

taattatcct gtatataagt ttaatatatc actttttaaa agaaaaaatt ctaccatttt   1620

aaattcatgt ttcaactcct acaaccaaat gagaaaaatc agggatgagc agctttatcc   1680

catttggggt atttttgtaa gtgatttaca tgtgtcaatt ttagtaatac ttttactttt   1740

ttgtaacttc atccttcata tatgcttgct atacaggtat gttcatcttt gtgtacagag   1800

gtttaataaa ttagttttca tatacataat ct                                 1832


<210>  8165
<211>  318
<212>  PRT
<213>  Homo sapiens

<400>  8165

Met Gln Ala Cys Gln Gln Lys Asp Val Phe Ala Asn Tyr Leu Thr Ser 
1               5                   10                  15


Asn Phe Gln Ala Pro Gly Val Lys Ser Gly Asn Lys Arg Ser Ser Ser 
            20                  25                  30


His Ser Ser Pro Gly Ser Pro Lys Lys Gln Lys Asn Glu Ser Asn Ser 
        35                  40                  45


Ala Gly Ser Pro Ala Asp Met Glu Leu Asp Ser Asp Met Glu Val Pro 
    50                  55                  60


His Gly Ser Gln Ser Ser Glu Ser Phe Gln Phe Gln Pro Pro Leu Pro 
65                  70                  75                  80


Pro Asp Thr Pro Pro Leu Pro Arg Gly Thr Pro Pro Pro Val Phe Thr 
                85                  90                  95


Pro Pro Leu Pro Lys Gly Thr Pro Pro Leu Thr Pro Ser Asp Ser Pro 
            100                 105                 110


Gln Thr Arg Thr Ala Ser Gly Ala Val Asp Glu Asp Ala Leu Thr Leu 
        115                 120                 125


Glu Glu Leu Glu Glu Gln Gln Arg Arg Ile Trp Ala Ala Leu Glu Gln 
    130                 135                 140


Ala Glu Ser Val Asn Ser Asp Ser Asp Val Pro Val Asp Thr Pro Leu 
145                 150                 155                 160


Thr Gly Asn Ser Val Ala Ser Ser Pro Cys Pro Asn Glu Leu Asp Leu 
                165                 170                 175


Pro Val Pro Glu Gly Lys Thr Ser Glu Lys Gln Thr Leu Asp Glu Pro 
            180                 185                 190


Glu Val Pro Glu Ile Phe Thr Lys Lys Ser Glu Ala Gly His Ala Ser 
        195                 200                 205


Ser Pro Asp Ser Glu Val Thr Ser Leu Cys Gln Lys Glu Lys Ala Glu 
    210                 215                 220


Leu Ala Pro Val Asn Thr Glu Gly Ala Leu Leu Asp Asn Gly Ser Val 
225                 230                 235                 240


Val Pro Asn Cys Asp Ile Ser Asn Gly Gly Ser Gln Lys Leu Phe Pro 
                245                 250                 255


Ala Asp Thr Ser Pro Ser Thr Ala Thr Lys Ile His Ser Pro Ile Pro 
            260                 265                 270


Asp Met Ser Lys Phe Ala Thr Gly Ile Thr Pro Phe Glu Phe Glu Asn 
        275                 280                 285


Met Ala Glu Ser Thr Gly Met Tyr Leu Arg Ile Arg Ser Leu Leu Lys 
    290                 295                 300


Asn Ser Pro Arg Asn Gln Gln Lys Asn Lys Lys Ala Ser Glu 
305                 310                 315


<210>  8166
<211>  4767
<212>  DNA
<213>  Homo sapiens

<400>  8166
gtgcagcttt cgcggcctgc gtctggagaa aaccctagcg ggtggctccg tgcggccaga     60

gctctagaga gtggtgccgc cttccaacct tcttccccaa gccctggtgg ccggctccgc    120

ctcttctcga atcttttcca cagcccaaaa tggccgcaga ggtgtatttt ggcgatctag    180

agctcttcga gccgttcgac cacccagagg agtcgattcc gaagcccgtt cacactcgct    240

tcaaggacga cgacggcgac gaggaggacg aaaatggggt cggcgacgcg gagctacggg    300

agcggcttcg gcagtgcgag gagaccatcg agcagctccg cgccgagaat atcctttcct    360

ctcgctgggc cctgtcaccc gggtgtgggg ccggggcagc gccaggcgtg gggccggggc    420

agcgccgggc gagggcgagg gcgcgggcgg aagttccagg agggccagaa ttccaagtgc    480

tttctgtcac ccgccggcgg accgagagtc tagggttcgg ggcgcgcagg ctgcctcggc    540

gcagacctct tcccctcagg gaggccgtct cctgaccaga cccactcctg cctcccaccc    600

gggtgccgtg tttagggtta ttttaggctg ctcacctgac agattgtaca caagccctta    660

attgcccccc tctgtttgag gtcgtggtga ggtttcatat ttcgcagcca cgctcaaatt    720

gtgccgtcat gttacagttg taggtgatga aataccggct gcttagacgc gggatcggtt    780

tttataccgg ggcaaacgct agtggtccca gaatgcagag ttgggggcct caaggaatcc    840

gggtgtgctg agataattgg ttaattgctt gattaaaatt ggggattaat tttagagttc    900

ttccactcgg agctcgcttc tgtgctgaag atgctttgca acgccttgag gaaaacgcgc    960

caaagaagtt tctgttagac ttgagttaca agattgcaga tttttcttga tttgctagta   1020

tgtttttttt tacgttcgta gagttttata ggtagataga taactttggt tcgggtagtt   1080

ttccttttaa aatttgtaga gaactgaaag tggctgatat gttagctttt ttagggggac   1140

ggggtcgggg aatggagtct cagtctgttg cccaggctgg agtgcagtgg cgcgatctcg   1200

gctcactgca acctccgcct cccgggttca agcgattctc ctgcctcagc ctcccgaata   1260

gctgggatta caggcgcccg ccacggcgcc cagtcagtat atcagttttt aaggtttgtg   1320

aagcgcgatt tattttttca gaatgtcgtc ttcctccaca ttgtgaggaa aattttcaga   1380

atacaaaaag ttgaggccgg gcgctgtggc tcaagcctgt aatcccagca ctttgggagg   1440

ccgaggcggg tggatcatga ggtcaggagg atcatgagga tcaggtggat catgaggatc   1500

aggaggtcag cctggccaac atggtgaaac cccgtctcta ctaaaaatac aaaattagcc   1560

gggcgtggtg gcgcgtgctt gtaatcccag ctactcagga ggctgaggca ggagaatccc   1620

ttgaacctgg gaggcggagg ttgcagtgag ccaagatcac accattgcac tccagcctgg   1680

gcgacagggt gagactgtgt ctcaaaaaaa aaaaaaaaaa gttgaaagga ttctacagtg   1740

gacatccata gatttattcc aaattctaaa gttgttaaca gctcgttata ctgcattctc   1800

tttatcacat agtggttgtt gaaaggtttg acaggaacac tgatgcttca ataatggttt   1860

tggttcagtt tgttagtctg ttgaacttca ggatcgtgtc ttagaatata tgttcgaaag   1920

gataaaaacc gtactttaat tttgggtttc aaaagcctac ccctgcaaca aaatagaagc   1980

tcaataagtg tgtcatcctc aaaatatccg tgggtctttt gtctttataa tattctgaca   2040

ccaaaagtga gagaagtagt agttgaattt tatgatttgc attgttaaat gagggcttat   2100

cttccttaac aaataataac atcaagaact taaacgaaaa ttgaacattc tgactcgacc   2160

gagtggaata ttggtgaacg atactaagtt agatggacct atattacaga ttctattcat   2220

gaacaatgct atttcaaagc aatatcatca agaaatagag gaatttgtat caaatttagt   2280

aaaaagattt gaggaacagc agaaaaatga tgtggaaaag acttccttta atcttttgcc   2340

ccagccatcc agtattgtgc tagaggagga ccacaaagtg gaagagtcct gtgccattaa   2400

aaacaacaag gaagctttca gtgttgtagg aagtgtcctg tattttacta atttttgcct   2460

tgataaattg gggcaaccgc ttctaaatga aaaccctcag ctttccgaag gatgggaaat   2520

acccaagtat cctacatagt gaatgaagat cttttatgca tcttgccact aagttcacct   2580

ttaaaacaat ttccaaattt tgcagaccat gataactatt ccttaataaa attcactaaa   2640

ggtaccatca agtcttcagc cacattgttt ctctagaagg gcaagaaata caagtaaagg   2700

caaaaaggcc aaagcctcac tgtttcaatt gtggttctga agaacaccaa atgaaagatt   2760

gcccaatgcc tcggaatgct gctcgaataa gtgaaaagag aaaagagtat atggatgcct   2820

gtggagaagc aaacaatcag aatttccagc agcgatacca cgcagaagaa gtagaagaaa   2880

gatttggaag attcaagcca ggagttatta gtgaggaact tcaagatgca ctaggtgtga   2940

cagacaagag tcttccacct tttatctatc ggatgcgcca gctagggtac ccaccagggt   3000

ggctcaaaga ggctgaattg gagaattcgg ggcttgcact ctatgatgga aaagatggca   3060

ctgatgggga aacagaagtt ggagaaatac aacagaataa aagtgtcact tacgatctct   3120

caaaattggt caactatcct ggttttaata tatctactcc cagaggaatt ccagacgaat   3180

ggaggatctt tggttccata ccaatgcagg catgtcagca gaaggatgtg tttgccaatt   3240

accttacttc taacttccaa gcgccaggtg tgaagtctgg caacaagagg tcttcatctc   3300

actctagccc aggtagtcca aagaagcaga agaatgaaag caactcagcg ggatctcccg   3360

ccgacatgga gctcgattca gatatggagg taccacatgg ttctcagagc agcgaaagtt   3420

ttcagtttca accaccatta cctcctgaca ctcctccact cccccgggga actcctccac   3480

ccgtcttcac ccctccactc ccaaagggca ccccgccgct gactcccagt gactcacccc   3540

agaccagaac agcatctgga gctgtggatg aggacgcact gactctagaa gaacttgaag   3600

aacagcagag gcggatctgg gcagctcttg agcaggccga gagcgtaaac agcgactccg   3660

acgttcctgt ggacacacct ttaactggca attccgttgc ctcatcacct tgtccaaatg   3720

agctagacct ccctgtcccg gagggaaaaa catctgaaaa gcagacgctg gatgagcctg   3780

aggtaccaga gatttttaca aagaaatcag aagctggaca tgcctccagt ccagactctg   3840

aggtgacatc actttgtcag aaggaaaaag cagagttggc tccggtaaac actgaaggtg   3900

cccttcttga taatggcagt gtcgtaccaa actgtgacat cagcaatggg ggcagccaga   3960

agctctttcc tgcagacacc agtccttcaa cggccactaa aattcatagc cctatacctg   4020

acatgagcaa atttgcaact ggaatcacgc catttgaatt tgagaatatg gcagaatcta   4080

ctggaatgta cctcaggata agaagcttgt taaagaactc accccgaaac cagcagaaaa   4140

acaaaaaggc ctctgaataa tggcttgact tagcactgag agctatttaa taactttgtt   4200

ccgttaatta gtactaatta agtggataga tagaatggtt ttcctgtttg tccctcccat   4260

gtttaaaaat ctatccaagg ttcatgttcc aaagtcaagc ctattttaaa gaaagactga   4320

gctcactagt tcagtatatt ttattctcac tgacaaaact tggggggaga tgtgaatatg   4380

acctggttta gagagggttt gttaaggttt atactatttt tggattgtga ctatccgtcg   4440

agagtgatgg tttttatctg tcttttgtac attgttttcc ctttctacat tttgctaatt   4500

atcctgtata taagtttaat atatcacttt ttaaaagaaa aaattctacc attttaaatt   4560

catgtttcaa ctcctacaac caaatgagaa aaatcaggga tgagcagctt tatcccattt   4620

ggggtatttt tgtaagtgat ttacatgtgt caattttagt aatactttta cttttttgta   4680

acttcatcct tcatatatgc ttgctataca ggtatgttca tctttgtgta cagaggttta   4740

ataaattagt tttcatatac ataatct                                       4767


<210>  8167
<211>  469
<212>  PRT
<213>  Homo sapiens

<400>  8167

Met Lys Asp Cys Pro Met Pro Arg Asn Ala Ala Arg Ile Ser Glu Lys 
1               5                   10                  15


Arg Lys Glu Tyr Met Asp Ala Cys Gly Glu Ala Asn Asn Gln Asn Phe 
            20                  25                  30


Gln Gln Arg Tyr His Ala Glu Glu Val Glu Glu Arg Phe Gly Arg Phe 
        35                  40                  45


Lys Pro Gly Val Ile Ser Glu Glu Leu Gln Asp Ala Leu Gly Val Thr 
    50                  55                  60


Asp Lys Ser Leu Pro Pro Phe Ile Tyr Arg Met Arg Gln Leu Gly Tyr 
65                  70                  75                  80


Pro Pro Gly Trp Leu Lys Glu Ala Glu Leu Glu Asn Ser Gly Leu Ala 
                85                  90                  95


Leu Tyr Asp Gly Lys Asp Gly Thr Asp Gly Glu Thr Glu Val Gly Glu 
            100                 105                 110


Ile Gln Gln Asn Lys Ser Val Thr Tyr Asp Leu Ser Lys Leu Val Asn 
        115                 120                 125


Tyr Pro Gly Phe Asn Ile Ser Thr Pro Arg Gly Ile Pro Asp Glu Trp 
    130                 135                 140


Arg Ile Phe Gly Ser Ile Pro Met Gln Ala Cys Gln Gln Lys Asp Val 
145                 150                 155                 160


Phe Ala Asn Tyr Leu Thr Ser Asn Phe Gln Ala Pro Gly Val Lys Ser 
                165                 170                 175


Gly Asn Lys Arg Ser Ser Ser His Ser Ser Pro Gly Ser Pro Lys Lys 
            180                 185                 190


Gln Lys Asn Glu Ser Asn Ser Ala Gly Ser Pro Ala Asp Met Glu Leu 
        195                 200                 205


Asp Ser Asp Met Glu Val Pro His Gly Ser Gln Ser Ser Glu Ser Phe 
    210                 215                 220


Gln Phe Gln Pro Pro Leu Pro Pro Asp Thr Pro Pro Leu Pro Arg Gly 
225                 230                 235                 240


Thr Pro Pro Pro Val Phe Thr Pro Pro Leu Pro Lys Gly Thr Pro Pro 
                245                 250                 255


Leu Thr Pro Ser Asp Ser Pro Gln Thr Arg Thr Ala Ser Gly Ala Val 
            260                 265                 270


Asp Glu Asp Ala Leu Thr Leu Glu Glu Leu Glu Glu Gln Gln Arg Arg 
        275                 280                 285


Ile Trp Ala Ala Leu Glu Gln Ala Glu Ser Val Asn Ser Asp Ser Asp 
    290                 295                 300


Val Pro Val Asp Thr Pro Leu Thr Gly Asn Ser Val Ala Ser Ser Pro 
305                 310                 315                 320


Cys Pro Asn Glu Leu Asp Leu Pro Val Pro Glu Gly Lys Thr Ser Glu 
                325                 330                 335


Lys Gln Thr Leu Asp Glu Pro Glu Val Pro Glu Ile Phe Thr Lys Lys 
            340                 345                 350


Ser Glu Ala Gly His Ala Ser Ser Pro Asp Ser Glu Val Thr Ser Leu 
        355                 360                 365


Cys Gln Lys Glu Lys Ala Glu Leu Ala Pro Val Asn Thr Glu Gly Ala 
    370                 375                 380


Leu Leu Asp Asn Gly Ser Val Val Pro Asn Cys Asp Ile Ser Asn Gly 
385                 390                 395                 400


Gly Ser Gln Lys Leu Phe Pro Ala Asp Thr Ser Pro Ser Thr Ala Thr 
                405                 410                 415


Lys Ile His Ser Pro Ile Pro Asp Met Ser Lys Phe Ala Thr Gly Ile 
            420                 425                 430


Thr Pro Phe Glu Phe Glu Asn Met Ala Glu Ser Thr Gly Met Tyr Leu 
        435                 440                 445


Arg Ile Arg Ser Leu Leu Lys Asn Ser Pro Arg Asn Gln Gln Lys Asn 
    450                 455                 460


Lys Lys Ala Ser Glu 
465


<210>  8168
<211>  2964
<212>  DNA
<213>  Homo sapiens

<400>  8168
atgccgtcct ccgggcaatc gcaagcccga taggccccgc tgcattccgg gagttgtagt     60

ctctagcgac tggccccgcc ccgtgtgcag ctttcgcggc ctgcgtctgg agaaaaccct    120

agcgggtggc tccgtgcggc cagagctcta gagagtggtg ccgccttcca accttcttcc    180

ccaagccctg gtggccggct ccgcctcttc tcgaatcttt tccacagccc aaaatggccg    240

cagaggtgta ttttggcgat ctagagctct tcgagccgtt cgaccaccca gaggagtcga    300

ttccgaagcc cgttcacact cgcttcaagg acgacgacgg cgacgaggag gacgaaaatg    360

gggtcggcga cgcggagcta cgggagcggc ttcggcagtg cgaggagacc atcgagcagc    420

tccgcgccga gaatcaagaa cttaaacgaa aattgaacat tctgactcga ccgagtggaa    480

tattggtgaa cgatactaag ttagatggac ctatattaca gattctattc atgaacaatg    540

ctatttcaaa gcaatatcat caagaaatag aggaatttgt atcaaattta gtaaaaagat    600

ttgaggaaca gcagaaaaat gatgtggaaa agacttcctt taatcttttg ccccagccat    660

ccagtattgt gctagaggag gaccacaaag tggaagagtc ctgtgccatt aaaaacaaca    720

aggaagcttt cagtgttgta ggaagtgtcc tgtattttac taatttttgc cttgataaat    780

tggggcaacc gcttctaaat gaaaaccctc agctttccga aggatgggaa atacccaagt    840

accatcaagt cttcagccac attgtttctc tagaagggca agaaatacaa gtaaaggcaa    900

aaaggccaaa gcctcactgt ttcaattgtg gttctgaaga acaccaaatg aaagattgcc    960

caatgcctcg gaatgctgct cgaataagtg aaaagagaaa agagtatatg gatgcctgtg   1020

gagaagcaaa caatcagaat ttccagcagc gataccacgc agaagaagta gaagaaagat   1080

ttggaagatt caagccagga gttattagtg aggaacttca agatgcacta ggtgtgacag   1140

acaagagtct tccacctttt atctatcgga tgcgccagct agggtaccca ccagggtggc   1200

tcaaagaggc tgaattggag aattcggggc ttgcactcta tgatggaaaa gatggcactg   1260

atggggaaac agaagttgga gaaatacaac agaataaaag tgtcacttac gatctctcaa   1320

aattggtcaa ctatcctggt tttaatatat ctactcccag aggaattcca gacgaatgga   1380

ggatctttgg ttccatacca atgcaggcat gtcagcagaa ggatgtgttt gccaattacc   1440

ttacttctaa cttccaagcg ccaggtgtga agtctggcaa caagaggtct tcatctcact   1500

ctagcccagg tagtccaaag aagcagaaga atgaaagcaa ctcagcggga tctcccgccg   1560

acatggagct cgattcagat atggaggtac cacatggttc tcagagcagc gaaagttttc   1620

agtttcaacc accattacct cctgacactc ctccactccc ccggggaact cctccacccg   1680

tcttcacccc tccactccca aagggcaccc cgccgctgac tcccagtgac tcaccccaga   1740

ccagaacagc atctggagct gtggatgagg acgcactgac tctagaagaa cttgaagaac   1800

agcagaggcg gatctgggca gctcttgagc aggccgagag cgtaaacagc gactccgacg   1860

ttcctgtgga cacaccttta actggcaatt ccgttgcctc atcaccttgt ccaaatgagc   1920

tagacctccc tgtcccggag ggaaaaacat ctgaaaagca gacgctggat gagcctgagg   1980

taccagagat ttttacaaag aaatcagaag ctggacatgc ctccagtcca gactctgagg   2040

tgacatcact ttgtcagaag gaaaaagcag agttggctcc ggtaaacact gaaggtgccc   2100

ttcttgataa tggcagtgtc gtaccaaact gtgacatcag caatgggggc agccagaagc   2160

tctttcctgc agacaccagt ccttcaacgg ccactaaaat tcatagccct atacctgaca   2220

tgagcaaatt tgcaactgga atcacgccat ttgaatttga gaatatggca gaatctactg   2280

gaatgtacct caggataaga agcttgttaa agaactcacc ccgaaaccag cagaaaaaca   2340

aaaaggcctc tgaataatgg cttgacttag cactgagagc tatttaataa ctttgttccg   2400

ttaattagta ctaattaagt ggatagatag aatggttttc ctgtttgtcc ctcccatgtt   2460

taaaaatcta tccaaggttc atgttccaaa gtcaagccta ttttaaagaa agactgagct   2520

cactagttca gtatatttta ttctcactga caaaacttgg ggggagatgt gaatatgacc   2580

tggtttagag agggtttgtt aaggtttata ctatttttgg attgtgacta tccgtcgaga   2640

gtgatggttt ttatctgtct tttgtacatt gttttccctt tctacatttt gctaattatc   2700

ctgtatataa gtttaatata tcacttttta aaagaaaaaa ttctaccatt ttaaattcat   2760

gtttcaactc ctacaaccaa atgagaaaaa tcagggatga gcagctttat cccatttggg   2820

gtatttttgt aagtgattta catgtgtcaa ttttagtaat acttttactt ttttgtaact   2880

tcatccttca tatatgcttg ctatacaggt atgttcatct ttgtgtacag aggtttaata   2940

aattagtttt catatacata atct                                          2964


<210>  8169
<211>  707
<212>  PRT
<213>  Homo sapiens

<400>  8169

Met Ala Ala Glu Val Tyr Phe Gly Asp Leu Glu Leu Phe Glu Pro Phe 
1               5                   10                  15


Asp His Pro Glu Glu Ser Ile Pro Lys Pro Val His Thr Arg Phe Lys 
            20                  25                  30


Asp Asp Asp Gly Asp Glu Glu Asp Glu Asn Gly Val Gly Asp Ala Glu 
        35                  40                  45


Leu Arg Glu Arg Leu Arg Gln Cys Glu Glu Thr Ile Glu Gln Leu Arg 
    50                  55                  60


Ala Glu Asn Gln Glu Leu Lys Arg Lys Leu Asn Ile Leu Thr Arg Pro 
65                  70                  75                  80


Ser Gly Ile Leu Val Asn Asp Thr Lys Leu Asp Gly Pro Ile Leu Gln 
                85                  90                  95


Ile Leu Phe Met Asn Asn Ala Ile Ser Lys Gln Tyr His Gln Glu Ile 
            100                 105                 110


Glu Glu Phe Val Ser Asn Leu Val Lys Arg Phe Glu Glu Gln Gln Lys 
        115                 120                 125


Asn Asp Val Glu Lys Thr Ser Phe Asn Leu Leu Pro Gln Pro Ser Ser 
    130                 135                 140


Ile Val Leu Glu Glu Asp His Lys Val Glu Glu Ser Cys Ala Ile Lys 
145                 150                 155                 160


Asn Asn Lys Glu Ala Phe Ser Val Val Gly Ser Val Leu Tyr Phe Thr 
                165                 170                 175


Asn Phe Cys Leu Asp Lys Leu Gly Gln Pro Leu Leu Asn Glu Asn Pro 
            180                 185                 190


Gln Leu Ser Glu Gly Trp Glu Ile Pro Lys Tyr His Gln Val Phe Ser 
        195                 200                 205


His Ile Val Ser Leu Glu Gly Gln Glu Ile Gln Val Lys Ala Lys Arg 
    210                 215                 220


Pro Lys Pro His Cys Phe Asn Cys Gly Ser Glu Glu His Gln Met Lys 
225                 230                 235                 240


Asp Cys Pro Met Pro Arg Asn Ala Ala Arg Ile Ser Glu Lys Arg Lys 
                245                 250                 255


Glu Tyr Met Asp Ala Cys Gly Glu Ala Asn Asn Gln Asn Phe Gln Gln 
            260                 265                 270


Arg Tyr His Ala Glu Glu Val Glu Glu Arg Phe Gly Arg Phe Lys Pro 
        275                 280                 285


Gly Val Ile Ser Glu Glu Leu Gln Asp Ala Leu Gly Val Thr Asp Lys 
    290                 295                 300


Ser Leu Pro Pro Phe Ile Tyr Arg Met Arg Gln Leu Gly Tyr Pro Pro 
305                 310                 315                 320


Gly Trp Leu Lys Glu Ala Glu Leu Glu Asn Ser Gly Leu Ala Leu Tyr 
                325                 330                 335


Asp Gly Lys Asp Gly Thr Asp Gly Glu Thr Glu Val Gly Glu Ile Gln 
            340                 345                 350


Gln Asn Lys Ser Val Thr Tyr Asp Leu Ser Lys Leu Val Asn Tyr Pro 
        355                 360                 365


Gly Phe Asn Ile Ser Thr Pro Arg Gly Ile Pro Asp Glu Trp Arg Ile 
    370                 375                 380


Phe Gly Ser Ile Pro Met Gln Ala Cys Gln Gln Lys Asp Val Phe Ala 
385                 390                 395                 400


Asn Tyr Leu Thr Ser Asn Phe Gln Ala Pro Gly Val Lys Ser Gly Asn 
                405                 410                 415


Lys Arg Ser Ser Ser His Ser Ser Pro Gly Ser Pro Lys Lys Gln Lys 
            420                 425                 430


Asn Glu Ser Asn Ser Ala Gly Ser Pro Ala Asp Met Glu Leu Asp Ser 
        435                 440                 445


Asp Met Glu Val Pro His Gly Ser Gln Ser Ser Glu Ser Phe Gln Phe 
    450                 455                 460


Gln Pro Pro Leu Pro Pro Asp Thr Pro Pro Leu Pro Arg Gly Thr Pro 
465                 470                 475                 480


Pro Pro Val Phe Thr Pro Pro Leu Pro Lys Gly Thr Pro Pro Leu Thr 
                485                 490                 495


Pro Ser Asp Ser Pro Gln Thr Arg Thr Ala Ser Gly Ala Val Asp Glu 
            500                 505                 510


Asp Ala Leu Thr Leu Glu Glu Leu Glu Glu Gln Gln Arg Arg Ile Trp 
        515                 520                 525


Ala Ala Leu Glu Gln Ala Glu Ser Val Asn Ser Asp Ser Asp Val Pro 
    530                 535                 540


Val Asp Thr Pro Leu Thr Gly Asn Ser Val Ala Ser Ser Pro Cys Pro 
545                 550                 555                 560


Asn Glu Leu Asp Leu Pro Val Pro Glu Gly Lys Thr Ser Glu Lys Gln 
                565                 570                 575


Thr Leu Asp Glu Pro Glu Val Pro Glu Ile Phe Thr Lys Lys Ser Glu 
            580                 585                 590


Ala Gly His Ala Ser Ser Pro Asp Ser Glu Val Thr Ser Leu Cys Gln 
        595                 600                 605


Lys Glu Lys Ala Glu Leu Ala Pro Val Asn Thr Glu Gly Ala Leu Leu 
    610                 615                 620


Asp Asn Gly Ser Val Val Pro Asn Cys Asp Ile Ser Asn Gly Gly Ser 
625                 630                 635                 640


Gln Lys Leu Phe Pro Ala Asp Thr Ser Pro Ser Thr Ala Thr Lys Ile 
                645                 650                 655


His Ser Pro Ile Pro Asp Met Ser Lys Phe Ala Thr Gly Ile Thr Pro 
            660                 665                 670


Phe Glu Phe Glu Asn Met Ala Glu Ser Thr Gly Met Tyr Leu Arg Ile 
        675                 680                 685


Arg Ser Leu Leu Lys Asn Ser Pro Arg Asn Gln Gln Lys Asn Lys Lys 
    690                 695                 700


Ala Ser Glu 
705


<210>  8170
<211>  1407
<212>  DNA
<213>  Homo sapiens

<400>  8170
attccaagtg ctttctgtca cccgccggcg gaccgagagt ctagggttcg gggcgcgcag     60

gctgcctcgg cgcagacctc ttcccctcag ggaggccgtc tcctgaccag acccactcct    120

gcctcccacc cgggtgccgt gtttagggtt attttaggct gctcacctga cagattgtac    180

acaagccctt aattgccccc ctctgtttga ggtcgtggtg aggtttcata tttcgcagcc    240

acgctcaaat tgtgccgtca tgttacagtt gtaggtgatg aaataccggc tgcttagacg    300

cgggatcggt ttttataccg gggcaaacgc tagtggtccc agaatgcaga gttgggggcc    360

tcaaggaatc cgggtgtgct gagataattg gttaattgct tgattaaaat tggggattaa    420

ttttagagtt cttccactcg gagctcgctt ctgtgctgaa gatgctttgc aacgccttga    480

ggaaaacgcg ccaaagaagt ttctgttaga cttgagttac aagattgcag atttttcttg    540

atttgctatg gaatattggt gaacgatact aagttagatg gacctatatt acagattcta    600

ttcatgaaca atgctatttc aaagcaatat catcaagaaa tagaggaatt tgtatcaaat    660

ttagtaaaaa gatttgagga acagcagaaa aatgatgtgg aaaagacttc ctttaatctt    720

ttgccccagc catccagtat tgtgctagag gaggaccaca aagtggaaga gtcctgtgcc    780

attaaaaaca acaaggaagc tttcagtgtt gtaggaagtg tcctgtattt tactaatttt    840

tgccttgata aattggggca accgcttcta aatgaaaacc ctcagctttc cgaaggatgg    900

gaaataccca agtatcctac atagtgaatg aagatctttt atgcatcttg ccactaagtt    960

cacctttaaa acaatttcca aattttgcag accatgataa ctattcctta ataaaattca   1020

ctaaaggtac catcaagtct tcagccacat tgtttctcta gaagggcaag aaatacaagt   1080

aaaggcaaaa aggtttgtgt ggggagttgt tttgttttac ttatttactt ttttaaccaa   1140

aatcataaac ttttggcttg aaaagttcat gttctttact gctggtttac tctaaggtta   1200

attacagatt gagctagaat tttaatccat acatatatgt taaatgttta aatgaatcat   1260

ctgcttcctg gaattcattg gttctcacct aatgtgcctg ggtgggtgga aaggtataat   1320

tgttgctgtc aatttgattg cagtcttata accatctgcc ttctttccat gttacctaac   1380

ggaaatatga tcaatgtgtt caccttg                                       1407


<210>  8171
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  8171

Met Asn Asn Ala Ile Ser Lys Gln Tyr His Gln Glu Ile Glu Glu Phe 
1               5                   10                  15


Val Ser Asn Leu Val Lys Arg Phe Glu Glu Gln Gln Lys Asn Asp Val 
            20                  25                  30


Glu Lys Thr Ser Phe Asn Leu Leu Pro Gln Pro Ser Ser Ile Val Leu 
        35                  40                  45


Glu Glu Asp His Lys Val Glu Glu Ser Cys Ala Ile Lys Asn Asn Lys 
    50                  55                  60


Glu Ala Phe Ser Val Val Gly Ser Val Leu Tyr Phe Thr Asn Phe Cys 
65                  70                  75                  80


Leu Asp Lys Leu Gly Gln Pro Leu Leu Asn Glu Asn Pro Gln Leu Ser 
                85                  90                  95


Glu Gly Trp Glu Ile Pro Lys Tyr Pro Thr 
            100                 105


<210>  8172
<211>  1334
<212>  DNA
<213>  Homo sapiens

<400>  8172
atgccgtcct ccgggcaatc gcaagcccga taggccccgc tgcattccgg gagttgtagt     60

ctctagcgac tggccccgcc ccgtgtgcag ctttcgcggc ctgcgtctgg agaaaaccct    120

agcgggtggc tccgtgcggc cagagctcta gagagtggtg ccgccttcca accttcttcc    180

ccaagccctg gtggccggct ccgcctcttc tcgaatcttt tccacagccc aaaatggccg    240

cagaggtgta ttttggcgat ctagagctct tcgagccgtt cgaccaccca gaggagtcga    300

ttccgaagcc cgttcacact cgcttcaagg acgacgacgg cgacgaggag gacgaaaatg    360

gggtcggcga cgcggagcta cgggagcggc ttcggcagtg cgaggagacc atcgagcagc    420

tccgcgccga gaatcaagaa cttaaacgaa aattgaacat tctgactcga ccgagtggaa    480

tattggtgaa cgatactaag ttagatggac ctatattaca gattctattc atgaacaatg    540

ctatttcaaa gcaatatcat caagaaatag aggaatttgt atcaaattta gtaaaaagat    600

ttgaggaaca gcagaaaaat gatgtggaaa agacttcctt taatcttttg ccccagccat    660

ccagtattgt gctagaggag gaccacaaag tggaagagtc ctgtgccatt aaaaacaaca    720

aggaagcttt cagtgttgta ggaagtgtcc tgtattttac taatttttgc cttgataaat    780

tggggcaacc gcttctaaat gaaaaccctc agctttccga aggatgggaa atacccaagt    840

atcctacata gtgaatgaag atcttttatg catcttgcca ctaagttcac ctttaaaaca    900

atttccaaat tttgcagacc atgataacta ttccttaata aaattcacta aaggtaccat    960

caagtcttca gccacattgt ttctctagaa gggcaagaaa tacaagtaaa ggcaaaaagg   1020

tttgtgtggg gagttgtttt gttttactta tttacttttt taaccaaaat cataaacttt   1080

tggcttgaaa agttcatgtt ctttactgct ggtttactct aaggttaatt acagattgag   1140

ctagaatttt aatccataca tatatgttaa atgtttaaat gaatcatctg cttcctggaa   1200

ttcattggtt ctcacctaat gtgcctgggt gggtggaaag gtataattgt tgctgtcaat   1260

ttgattgcag tcttataacc atctgccttc tttccatgtt acctaacgga aatatgatca   1320

atgtgttcac cttg                                                     1334


<210>  8173
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  8173

Met Ala Ala Glu Val Tyr Phe Gly Asp Leu Glu Leu Phe Glu Pro Phe 
1               5                   10                  15


Asp His Pro Glu Glu Ser Ile Pro Lys Pro Val His Thr Arg Phe Lys 
            20                  25                  30


Asp Asp Asp Gly Asp Glu Glu Asp Glu Asn Gly Val Gly Asp Ala Glu 
        35                  40                  45


Leu Arg Glu Arg Leu Arg Gln Cys Glu Glu Thr Ile Glu Gln Leu Arg 
    50                  55                  60


Ala Glu Asn Gln Glu Leu Lys Arg Lys Leu Asn Ile Leu Thr Arg Pro 
65                  70                  75                  80


Ser Gly Ile Leu Val Asn Asp Thr Lys Leu Asp Gly Pro Ile Leu Gln 
                85                  90                  95


Ile Leu Phe Met Asn Asn Ala Ile Ser Lys Gln Tyr His Gln Glu Ile 
            100                 105                 110


Glu Glu Phe Val Ser Asn Leu Val Lys Arg Phe Glu Glu Gln Gln Lys 
        115                 120                 125


Asn Asp Val Glu Lys Thr Ser Phe Asn Leu Leu Pro Gln Pro Ser Ser 
    130                 135                 140


Ile Val Leu Glu Glu Asp His Lys Val Glu Glu Ser Cys Ala Ile Lys 
145                 150                 155                 160


Asn Asn Lys Glu Ala Phe Ser Val Val Gly Ser Val Leu Tyr Phe Thr 
                165                 170                 175


Asn Phe Cys Leu Asp Lys Leu Gly Gln Pro Leu Leu Asn Glu Asn Pro 
            180                 185                 190


Gln Leu Ser Glu Gly Trp Glu Ile Pro Lys Tyr Pro Thr 
        195                 200                 205


<210>  8174
<211>  361
<212>  DNA
<213>  Homo sapiens

<400>  8174
ggggcttcac catgttggcc aggctggtct cgaactcctg gcctcgagtg atctgtccac     60

ctcaacctcc caaagtgctg gaattaacag gcatgagcca ctgcacctgg cctcacatga    120

actttttagt ccctggcacc agttggaata actggctgca gtggtgacta caggtttaaa    180

ttttagaatt tagaaatatt tcagattttt tttttttgag atggagtctc gctctgtcgc    240

ccaggctgga gtgcagtggc atgacctcgg ctcactgcag cctccacctc ctgggttcaa    300

gcgattctgc tttctcctgc ctcaaaaaaa aaaaaaaaat taaagagtat atgtgaggcc    360

a                                                                    361


<210>  8175
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  8175

Met Glu Ser Arg Ser Val Ala Gln Ala Gly Val Gln Trp His Asp Leu 
1               5                   10                  15


Gly Ser Leu Gln Pro Pro Pro Pro Gly Phe Lys Arg Phe Cys Phe Leu 
            20                  25                  30


Leu Pro Gln Lys Lys Lys Lys Asn 
        35                  40


<210>  8176
<211>  571
<212>  DNA
<213>  Homo sapiens

<400>  8176
gtgcagcttt cgcggcctgc gtctggagaa aaccctagcg ggtggctccg tgcggccaga     60

gctctagaga gtggtgccgc cttccaacct tcttccccaa gccctggtgg ccggctccgc    120

ctcttctcga atcttttcca cagcccaaaa tggccgcaga ggtgtatttt ggcgatctag    180

agctcttcga gccgttcgac cacccagagg agtcgattcc gaagcccgtt cacactcgct    240

tcaaggacga cgacggcgac gaggaggacg aaaatggggt cggcgacgcg gagctacggg    300

agcggcttcg gcagtgcgag gagaccatcg agcagctccg cgccgagaat caagaactta    360

aacgaaaatt gaacattctg actcgaccga gtggaatatt ggtgaacgat actaagttag    420

atggacctat attacagatt ctattcatga acaatgctat ttcaaagtaa gtaatttttt    480

ccctttccta aatataataa tgtgtttatg gaacaatttt ctctataaat atgctgtttt    540

catttgtact catatcattt ttattatttt a                                   571


<210>  8177
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  8177

Met Ala Ala Glu Val Tyr Phe Gly Asp Leu Glu Leu Phe Glu Pro Phe 
1               5                   10                  15


Asp His Pro Glu Glu Ser Ile Pro Lys Pro Val His Thr Arg Phe Lys 
            20                  25                  30


Asp Asp Asp Gly Asp Glu Glu Asp Glu Asn Gly Val Gly Asp Ala Glu 
        35                  40                  45


Leu Arg Glu Arg Leu Arg Gln Cys Glu Glu Thr Ile Glu Gln Leu Arg 
    50                  55                  60


Ala Glu Asn Gln Glu Leu Lys Arg Lys Leu Asn Ile Leu Thr Arg Pro 
65                  70                  75                  80


Ser Gly Ile Leu Val Asn Asp Thr Lys Leu Asp Gly Pro Ile Leu Gln 
                85                  90                  95


Ile Leu Phe Met Asn Asn Ala Ile Ser Lys 
            100                 105


<210>  8178
<211>  2414
<212>  DNA
<213>  Homo sapiens

<400>  8178
aagctgtgcg acgcgccggg cctcctcgcc tttgtgccat ccgggtctct cgcgcgagcg     60

atttagtctg aggcgaagct tcggagcggc cggtactgtt gaaagcgaca agtggaggcg    120

ccgctctagc ggccgggact ctgaactatg gcggctagtg atacagagcg agatggacta    180

gccccagaaa agacatcacc agatagagat aagaaaaaag agcagtcaga agtatctgtt    240

tctcctagag cttcaaaaca tcattattca agatcacgat caaggtcaag agaaagaaaa    300

cgaaagtcag ataatgaagg aagaaaacac aggagccgga gcagaagcaa agagcgtgct    360

tatgcgcgaa gagactgaac tgaagacgct gcagactcag atagcaaaat aataagccta    420

cttcatgata agggaagaag acatgaatcc aaagataaat cctctaagaa acataagtct    480

gaggaacata atgacaaaga acattcttct gataaaggaa gagagcgact aaattcatct    540

gaaaatggtg aggacaggca caaacgcaaa gaaagaaagt catcaagagg cagaagtcac    600

tcaagatcta ggtctcgtga aagacgccat cgtagtagaa gcagggagcg gaagaagtct    660

cgatccagga gtagggagcg gaagaaatcg agatccagaa gcagagagag gaagaaatcg    720

agatccagaa gcagggaaag aaaacggcgg atcaggtctc gttcccgctc aagatcaaga    780

cacaggcata ggactagaag caggagtagg acaaggagta ggagtcgaga tagaaagaag    840

agaattgaaa agccgagaag atttagcaga agtttaagcc ggactccaag tccacctccc    900

ttcagaggca gaaacacagc aatggatgca caggaagctt tagctagaag gttggaaagg    960

gcaaagaaat tacaagaaca gcgagaaaag gaaatggttg aaaaacaaaa acaacaagaa   1020

atagctgcag ctgcagctac tggaggttct gttctcaatg ttgctgccct gttggcatca   1080

ggaacacaag taacacctca gatagccatg gcagctcaga tggcagccct gcaagctaaa   1140

gctttggcag agacaggaat agctgttcct agctactata acccagccgc tgttaatcca   1200

atgaaatttg ctgaacaaga gaaaaaaagg aaaatgcttt ggcagggcaa gaaagaaggg   1260

gacaaatccc aatctgctga aatatgggaa aaattgaatt ttggaaacaa ggaccaaaat   1320

gtcaaattta ggaaattgat gggtattaag agtgaagatg aagctggatg tagctcagtt   1380

gatgaagaaa gttacaagac tctgaagcag caggaagaag tatttcgaaa tttagatgct   1440

cagtatgaaa tggcaagatc acaaacccac acacaaagag gaatgggttt gggtttcaca   1500

tcttcaatgc gaggaatgga tgcagtttga aaatgatcac acttgtaaag tttgggactt   1560

atagacttct tgttctgatg tcacgtcctt gttcaccaaa cagctagcac tctagcttgc   1620

atgggtgttg cattgacttt aatttattga aaaatacaaa tttttgtaaa tatcagatca   1680

gtgatactgg tgttagtgtt gtaatcaggt taaacccact tccattaaac ttgacaggac   1740

tatagaagga taatattttt tagttcatga attctacttt tcaaatatat aaaagctgca   1800

ggtggggata aaatctcata catggatttt ttcgtgtccg ctgtcttgtg tacttttgta   1860

cttaaccttg tacagttatt ttcatctctt gaaacatgaa agaaatgtta tgtagatgtt   1920

ctttagaaga tctggccatt tggtacataa tccagcacag ataagctggg tggtaatgat   1980

aataaaaatg gttttctcaa aactggtgtt aatttaagtt acctgggatg tttctttgaa   2040

tttgttttat agtttctgta gcatttggca attgctgtta gaaaacacta gctagaaatc   2100

ccctccccac cacccttttt aaggccagtt aactatacta cagtcaatac cgtggtgagc   2160

aaaaatgtaa aaggtggaag gagaaaactt actaaaatag tatgttttcc tattataagg   2220

gacagacttg gtattcagta tttgtcaaat attacatgtg ttattcagga gatagattaa   2280

tgcattaaag ggatgtaagc acttttattt taataaagtg ccttataaca agttctttgc   2340

atgctttttg ctcattatcc ctttgaagtc ttctccagca tagactataa aatattaaaa   2400

tattagaaat tttt                                                     2414


<210>  8179
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  8179

Met Asp Ala Gln Glu Ala Leu Ala Arg Arg Leu Glu Arg Ala Lys Lys 
1               5                   10                  15


Leu Gln Glu Gln Arg Glu Lys Glu Met Val Glu Lys Gln Lys Gln Gln 
            20                  25                  30


Glu Ile Ala Ala Ala Ala Ala Thr Gly Gly Ser Val Leu Asn Val Ala 
        35                  40                  45


Ala Leu Leu Ala Ser Gly Thr Gln Val Thr Pro Gln Ile Ala Met Ala 
    50                  55                  60


Ala Gln Met Ala Ala Leu Gln Ala Lys Ala Leu Ala Glu Thr Gly Ile 
65                  70                  75                  80


Ala Val Pro Ser Tyr Tyr Asn Pro Ala Ala Val Asn Pro Met Lys Phe 
                85                  90                  95


Ala Glu Gln Glu Lys Lys Arg Lys Met Leu Trp Gln Gly Lys Lys Glu 
            100                 105                 110


Gly Asp Lys Ser Gln Ser Ala Glu Ile Trp Glu Lys Leu Asn Phe Gly 
        115                 120                 125


Asn Lys Asp Gln Asn Val Lys Phe Arg Lys Leu Met Gly Ile Lys Ser 
    130                 135                 140


Glu Asp Glu Ala Gly Cys Ser Ser Val Asp Glu Glu Ser Tyr Lys Thr 
145                 150                 155                 160


Leu Lys Gln Gln Glu Glu Val Phe Arg Asn Leu Asp Ala Gln Tyr Glu 
                165                 170                 175


Met Ala Arg Ser Gln Thr His Thr Gln Arg Gly Met Gly Leu Gly Phe 
            180                 185                 190


Thr Ser Ser Met Arg Gly Met Asp Ala Val 
        195                 200


<210>  8180
<211>  2347
<212>  DNA
<213>  Homo sapiens

<400>  8180
tttctcccag caagctgtgc gacgcgccgg gcctcctcgc ctttgtgcca tccgggtctc     60

tcgcgcgagc gatttagtct gaggcgaagc ttcggagcgg ccggtactgt tgaaagcgac    120

aagtggaggc gccgctctag cggccgggac tctgaactat ggcggctagt gatacagagc    180

gagatggact agccccagaa aagacatcac cagatagaga taagaaaaaa gagcagtcag    240

aagtatctgt ttctcctaga gcttcaaaac atcattattc aagatcacga tcaaggtcaa    300

gagaaagaaa acgaaagtca gataatgaag gaagaaaaca caggagccgg agcagaagca    360

aagagggaag aagacatgaa tccaaagata aatcctctaa gaaacataag tctgaggaac    420

ataatgacaa agaacattct tctgataaag gaagagagcg actaaattca tctgaaaatg    480

gtgaggacag gcacaaacgc aaagaaagaa agtcatcaag aggcagaagt cactcaagat    540

ctaggtctcg tgaaagacgc catcgtagta gaagcaggga gcggaagaag tctcgatcca    600

ggagtaggga gcggaagaaa tcgagatcca gaagcagaga gaggaagaaa tcgagatcca    660

gaagcaggga aagaaaacgg cggatcaggt ctcgttcccg ctcaagatca agacacaggc    720

ataggactag aagcaggagt aggacaagga gtaggagtcg agatagaaag aagagaattg    780

aaaagccgag aagatttagc agaagtttaa gccggactcc aagtccacct cccttcagag    840

gcagaaacac agcaatggat gcacaggaag ctttagctag aaggttggaa agggcaaaga    900

aattacaaga acagcgagaa aaggaaatgg ttgaaaaaca aaaacaacaa gaaatagctg    960

cagctgcagc tactggaggt tctgttctca atgttgctgc cctgttggca tcaggaacac   1020

aagtaacacc tcagatagcc atggcagctc agatggcagc cctgcaagct aaagctttgg   1080

cagagacagg aatagctgtt cctagctact ataacccagc cgctgttaat ccaatgaaat   1140

ttgctgaaca agagaaaaaa aggaaaatgc tttggcaggg caagaaagaa ggggacaaat   1200

cccaatctgc tgaaatatgg gaaaaattga attttggaaa caaggaccaa aatgtcaaat   1260

ttaggaaatt gatgggtatt aagagtgaag atgaagctgg atgtagctca gttgatgaag   1320

aaagttacaa gactctgaag cagcaggaag aagtatttcg aaatttagat gctcagtatg   1380

aaatggcaag atcacaaacc cacacacaaa gaggaatggg tttgggtttc acatcttcaa   1440

tgcgaggaat ggatgcagtt tgaaaatgat cacacttgta aagtttggga cttatagact   1500

tcttgttctg atgtcacgtc cttgttcacc aaacagctag cactctagct tgcatgggtg   1560

ttgcattgac tttaatttat tgaaaaatac aaatttttgt aaatatcaga tcagtgatac   1620

tggtgttagt gttgtaatca ggttaaaccc acttccatta aacttgacag gactatagaa   1680

ggataatatt ttttagttca tgaattctac ttttcaaata tataaaagct gcaggtgggg   1740

ataaaatctc atacatggat tttttcgtgt ccgctgtctt gtgtactttt gtacttaacc   1800

ttgtacagtt attttcatct cttgaaacat gaaagaaatg ttatgtagat gttctttaga   1860

agatctggcc atttggtaca taatccagca cagataagct gggtggtaat gataataaaa   1920

atggttttct caaaactggt gttaatttaa gttacctggg atgtttcttt gaatttgttt   1980

tatagtttct gtagcatttg gcaattgctg ttagaaaaca ctagctagaa atcccctccc   2040

caccaccctt tttaaggcca gttaactata ctacagtcaa taccgtggtg agcaaaaatg   2100

taaaaggtgg aaggagaaaa cttactaaaa tagtatgttt tcctattata agggacagac   2160

ttggtattca gtatttgtca aatattacat gtgttattca ggagatagat taatgcatta   2220

aagggatgta agcactttta ttttaataaa gtgccttata acaagttctt tgcatgcttt   2280

ttgctcatta tccctttgaa gtcttctcca gcatagacta taaaatatta aaatattaga   2340

aattttt                                                             2347


<210>  8181
<211>  434
<212>  PRT
<213>  Homo sapiens

<400>  8181

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Gly Arg Arg His Glu Ser Lys Asp Lys Ser Ser 
65                  70                  75                  80


Lys Lys His Lys Ser Glu Glu His Asn Asp Lys Glu His Ser Ser Asp 
                85                  90                  95


Lys Gly Arg Glu Arg Leu Asn Ser Ser Glu Asn Gly Glu Asp Arg His 
            100                 105                 110


Lys Arg Lys Glu Arg Lys Ser Ser Arg Gly Arg Ser His Ser Arg Ser 
        115                 120                 125


Arg Ser Arg Glu Arg Arg His Arg Ser Arg Ser Arg Glu Arg Lys Lys 
    130                 135                 140


Ser Arg Ser Arg Ser Arg Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg 
145                 150                 155                 160


Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg Glu Arg Lys Arg Arg Ile 
                165                 170                 175


Arg Ser Arg Ser Arg Ser Arg Ser Arg His Arg His Arg Thr Arg Ser 
            180                 185                 190


Arg Ser Arg Thr Arg Ser Arg Ser Arg Asp Arg Lys Lys Arg Ile Glu 
        195                 200                 205


Lys Pro Arg Arg Phe Ser Arg Ser Leu Ser Arg Thr Pro Ser Pro Pro 
    210                 215                 220


Pro Phe Arg Gly Arg Asn Thr Ala Met Asp Ala Gln Glu Ala Leu Ala 
225                 230                 235                 240


Arg Arg Leu Glu Arg Ala Lys Lys Leu Gln Glu Gln Arg Glu Lys Glu 
                245                 250                 255


Met Val Glu Lys Gln Lys Gln Gln Glu Ile Ala Ala Ala Ala Ala Thr 
            260                 265                 270


Gly Gly Ser Val Leu Asn Val Ala Ala Leu Leu Ala Ser Gly Thr Gln 
        275                 280                 285


Val Thr Pro Gln Ile Ala Met Ala Ala Gln Met Ala Ala Leu Gln Ala 
    290                 295                 300


Lys Ala Leu Ala Glu Thr Gly Ile Ala Val Pro Ser Tyr Tyr Asn Pro 
305                 310                 315                 320


Ala Ala Val Asn Pro Met Lys Phe Ala Glu Gln Glu Lys Lys Arg Lys 
                325                 330                 335


Met Leu Trp Gln Gly Lys Lys Glu Gly Asp Lys Ser Gln Ser Ala Glu 
            340                 345                 350


Ile Trp Glu Lys Leu Asn Phe Gly Asn Lys Asp Gln Asn Val Lys Phe 
        355                 360                 365


Arg Lys Leu Met Gly Ile Lys Ser Glu Asp Glu Ala Gly Cys Ser Ser 
    370                 375                 380


Val Asp Glu Glu Ser Tyr Lys Thr Leu Lys Gln Gln Glu Glu Val Phe 
385                 390                 395                 400


Arg Asn Leu Asp Ala Gln Tyr Glu Met Ala Arg Ser Gln Thr His Thr 
                405                 410                 415


Gln Arg Gly Met Gly Leu Gly Phe Thr Ser Ser Met Arg Gly Met Asp 
            420                 425                 430


Ala Val 



<210>  8182
<211>  2329
<212>  DNA
<213>  Homo sapiens

<400>  8182
aagctgtgcg acgcgccggg cctcctcgcc tttgtgccat ccgggtctct cgcgcgagcg     60

atttagtctg aggcgaagct tcggagcggc cggtactgtt gaaagcgaca agtggaggcg    120

ccgctctagc ggccgggact ctgaactatg gcggctagtg atacagagcg agatggacta    180

gccccagaaa agacatcacc agatagagat aagaaaaaag agcagtcaga agtatctgtt    240

tctcctagag cttcaaaaca tcattattca agatcacgat caaggtcaag agaaagaaaa    300

cgaaagtcag ataatgaagg aagaaaacac aggagccgga gcagaagcaa agagcgtgct    360

tatgcgcgaa gagactgaac tgaagacgct gcagactcag atagcaaaat aataagccta    420

cttcatgata agggaagaag acatgaatcc aaagataaat cctctaagaa acataagtct    480

gaggaacata atgacaaaga acattcttct gataaaggaa gagagcgact aaattcatct    540

gaaaatggtg aggacaggca caaacgcaaa gaaagaaagt catcaagagg cagaagtcac    600

tcaagatcta ggtctcgtga aagacgccat cgtagtagaa gcagggagcg gaagaagtct    660

cgatccagga gtagggagcg gaagaaatcg agatccagaa gcagagagag gaagaaatcg    720

agatccagaa gcagggaaag aaaacggcgg atcaggtctc gttcccgctc aagatcaaga    780

cacaggcata ggactagaag caggagtagg acaaggagta ggagtcgaga tagaaagaag    840

agaattgaaa agccgagaag atttagcaga agtttaagcc ggactccaag tccacctccc    900

ttcagaggca gaaacacagc aatggatgca caggaagctt tagctagaag gttggaaagg    960

gcaaagaaat tacaagaaca gcgagaaaag gaaatggttg aaaaacaaaa acaacaagaa   1020

atagctgcag ctgcagctac tggaggttct gttctcaatg ttgctgccct gttggcatca   1080

ggaacacaag taacacctca gatagccatg gcagctcaga tggcagccct gcaagctaaa   1140

gctttggcag agacaggaat agctgttcct agctactata acccagccgc tgttaatcca   1200

atgaaatttg ctgaacaaga gaaaaaaagg aaaatgcttt ggcagggcaa gaaagaaggg   1260

gacaaatccc aatctgctga aatatgggaa aaattgaatt ttggaaacaa ggaccaaaat   1320

gtcaaattta ggaaattgat gggtattaag agtgaagatg aagctggatg tagctcagtt   1380

gatgaagaaa gttacaagac tctgaagcag caggaagaag tatttcgaaa tttagatgct   1440

cagtatgaaa tggcaagatc acaaacccac acacaaagag gaatgggttt gggtttcaca   1500

tcttcaatgc gaggaatgga tgcagtttga aaatgatcac acttgtaaag tttgggactt   1560

atagacttct tgttctgatg tcacgtcctt gttcaccaaa cagctagcac tctagcttgc   1620

atgggtgttg cattgacttt aatttattga aaaatacaaa tttttgtaaa tatcagatca   1680

gtgatactgg tgttagtgtt gtaatcaggt taaacccact tccattaaac ttgacaggac   1740

tatagaagga taatattttt tagttcatga attctacttt tcaaatatat aaaagctgca   1800

ggtggggata aaatctcata catggatttt ttcgtgtccg ctgtcttgtg tacttttgta   1860

cttaaccttg tacagttatt ttcatctctt gaaacatgaa agaaatgtta tgtagatgtt   1920

ctttagaaga tctggccatt tggtacataa tccagcacag ataagctggg tggtaatgat   1980

aataaaaatg gttttctcaa aactggtgtt aatttaagtt acctgggatg tttctttgaa   2040

tttgttttat agtttctgta gcatttggca attgctgtta gaaaacacta gctagaaatc   2100

ccctccccac cacccttttt aaggccagtt aactatacta cagtcaatac cgtggtgagc   2160

aaaaatgtaa aaggtggaag gagaaaactt actaaaatag tatgttttcc tattataagg   2220

gacagacttg gtattcagta tttgtcaaat attacatgtg ttattcagga gatagattaa   2280

tgcattaaag ggatgtaagc acttttattt taataaagtg ccttataac               2329


<210>  8183
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  8183

Met Asp Ala Gln Glu Ala Leu Ala Arg Arg Leu Glu Arg Ala Lys Lys 
1               5                   10                  15


Leu Gln Glu Gln Arg Glu Lys Glu Met Val Glu Lys Gln Lys Gln Gln 
            20                  25                  30


Glu Ile Ala Ala Ala Ala Ala Thr Gly Gly Ser Val Leu Asn Val Ala 
        35                  40                  45


Ala Leu Leu Ala Ser Gly Thr Gln Val Thr Pro Gln Ile Ala Met Ala 
    50                  55                  60


Ala Gln Met Ala Ala Leu Gln Ala Lys Ala Leu Ala Glu Thr Gly Ile 
65                  70                  75                  80


Ala Val Pro Ser Tyr Tyr Asn Pro Ala Ala Val Asn Pro Met Lys Phe 
                85                  90                  95


Ala Glu Gln Glu Lys Lys Arg Lys Met Leu Trp Gln Gly Lys Lys Glu 
            100                 105                 110


Gly Asp Lys Ser Gln Ser Ala Glu Ile Trp Glu Lys Leu Asn Phe Gly 
        115                 120                 125


Asn Lys Asp Gln Asn Val Lys Phe Arg Lys Leu Met Gly Ile Lys Ser 
    130                 135                 140


Glu Asp Glu Ala Gly Cys Ser Ser Val Asp Glu Glu Ser Tyr Lys Thr 
145                 150                 155                 160


Leu Lys Gln Gln Glu Glu Val Phe Arg Asn Leu Asp Ala Gln Tyr Glu 
                165                 170                 175


Met Ala Arg Ser Gln Thr His Thr Gln Arg Gly Met Gly Leu Gly Phe 
            180                 185                 190


Thr Ser Ser Met Arg Gly Met Asp Ala Val 
        195                 200


<210>  8184
<211>  2262
<212>  DNA
<213>  Homo sapiens

<400>  8184
tttctcccag caagctgtgc gacgcgccgg gcctcctcgc ctttgtgcca tccgggtctc     60

tcgcgcgagc gatttagtct gaggcgaagc ttcggagcgg ccggtactgt tgaaagcgac    120

aagtggaggc gccgctctag cggccgggac tctgaactat ggcggctagt gatacagagc    180

gagatggact agccccagaa aagacatcac cagatagaga taagaaaaaa gagcagtcag    240

aagtatctgt ttctcctaga gcttcaaaac atcattattc aagatcacga tcaaggtcaa    300

gagaaagaaa acgaaagtca gataatgaag gaagaaaaca caggagccgg agcagaagca    360

aagagggaag aagacatgaa tccaaagata aatcctctaa gaaacataag tctgaggaac    420

ataatgacaa agaacattct tctgataaag gaagagagcg actaaattca tctgaaaatg    480

gtgaggacag gcacaaacgc aaagaaagaa agtcatcaag aggcagaagt cactcaagat    540

ctaggtctcg tgaaagacgc catcgtagta gaagcaggga gcggaagaag tctcgatcca    600

ggagtaggga gcggaagaaa tcgagatcca gaagcagaga gaggaagaaa tcgagatcca    660

gaagcaggga aagaaaacgg cggatcaggt ctcgttcccg ctcaagatca agacacaggc    720

ataggactag aagcaggagt aggacaagga gtaggagtcg agatagaaag aagagaattg    780

aaaagccgag aagatttagc agaagtttaa gccggactcc aagtccacct cccttcagag    840

gcagaaacac agcaatggat gcacaggaag ctttagctag aaggttggaa agggcaaaga    900

aattacaaga acagcgagaa aaggaaatgg ttgaaaaaca aaaacaacaa gaaatagctg    960

cagctgcagc tactggaggt tctgttctca atgttgctgc cctgttggca tcaggaacac   1020

aagtaacacc tcagatagcc atggcagctc agatggcagc cctgcaagct aaagctttgg   1080

cagagacagg aatagctgtt cctagctact ataacccagc cgctgttaat ccaatgaaat   1140

ttgctgaaca agagaaaaaa aggaaaatgc tttggcaggg caagaaagaa ggggacaaat   1200

cccaatctgc tgaaatatgg gaaaaattga attttggaaa caaggaccaa aatgtcaaat   1260

ttaggaaatt gatgggtatt aagagtgaag atgaagctgg atgtagctca gttgatgaag   1320

aaagttacaa gactctgaag cagcaggaag aagtatttcg aaatttagat gctcagtatg   1380

aaatggcaag atcacaaacc cacacacaaa gaggaatggg tttgggtttc acatcttcaa   1440

tgcgaggaat ggatgcagtt tgaaaatgat cacacttgta aagtttggga cttatagact   1500

tcttgttctg atgtcacgtc cttgttcacc aaacagctag cactctagct tgcatgggtg   1560

ttgcattgac tttaatttat tgaaaaatac aaatttttgt aaatatcaga tcagtgatac   1620

tggtgttagt gttgtaatca ggttaaaccc acttccatta aacttgacag gactatagaa   1680

ggataatatt ttttagttca tgaattctac ttttcaaata tataaaagct gcaggtgggg   1740

ataaaatctc atacatggat tttttcgtgt ccgctgtctt gtgtactttt gtacttaacc   1800

ttgtacagtt attttcatct cttgaaacat gaaagaaatg ttatgtagat gttctttaga   1860

agatctggcc atttggtaca taatccagca cagataagct gggtggtaat gataataaaa   1920

atggttttct caaaactggt gttaatttaa gttacctggg atgtttcttt gaatttgttt   1980

tatagtttct gtagcatttg gcaattgctg ttagaaaaca ctagctagaa atcccctccc   2040

caccaccctt tttaaggcca gttaactata ctacagtcaa taccgtggtg agcaaaaatg   2100

taaaaggtgg aaggagaaaa cttactaaaa tagtatgttt tcctattata agggacagac   2160

ttggtattca gtatttgtca aatattacat gtgttattca ggagatagat taatgcatta   2220

aagggatgta agcactttta ttttaataaa gtgccttata ac                      2262


<210>  8185
<211>  434
<212>  PRT
<213>  Homo sapiens

<400>  8185

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Gly Arg Arg His Glu Ser Lys Asp Lys Ser Ser 
65                  70                  75                  80


Lys Lys His Lys Ser Glu Glu His Asn Asp Lys Glu His Ser Ser Asp 
                85                  90                  95


Lys Gly Arg Glu Arg Leu Asn Ser Ser Glu Asn Gly Glu Asp Arg His 
            100                 105                 110


Lys Arg Lys Glu Arg Lys Ser Ser Arg Gly Arg Ser His Ser Arg Ser 
        115                 120                 125


Arg Ser Arg Glu Arg Arg His Arg Ser Arg Ser Arg Glu Arg Lys Lys 
    130                 135                 140


Ser Arg Ser Arg Ser Arg Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg 
145                 150                 155                 160


Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg Glu Arg Lys Arg Arg Ile 
                165                 170                 175


Arg Ser Arg Ser Arg Ser Arg Ser Arg His Arg His Arg Thr Arg Ser 
            180                 185                 190


Arg Ser Arg Thr Arg Ser Arg Ser Arg Asp Arg Lys Lys Arg Ile Glu 
        195                 200                 205


Lys Pro Arg Arg Phe Ser Arg Ser Leu Ser Arg Thr Pro Ser Pro Pro 
    210                 215                 220


Pro Phe Arg Gly Arg Asn Thr Ala Met Asp Ala Gln Glu Ala Leu Ala 
225                 230                 235                 240


Arg Arg Leu Glu Arg Ala Lys Lys Leu Gln Glu Gln Arg Glu Lys Glu 
                245                 250                 255


Met Val Glu Lys Gln Lys Gln Gln Glu Ile Ala Ala Ala Ala Ala Thr 
            260                 265                 270


Gly Gly Ser Val Leu Asn Val Ala Ala Leu Leu Ala Ser Gly Thr Gln 
        275                 280                 285


Val Thr Pro Gln Ile Ala Met Ala Ala Gln Met Ala Ala Leu Gln Ala 
    290                 295                 300


Lys Ala Leu Ala Glu Thr Gly Ile Ala Val Pro Ser Tyr Tyr Asn Pro 
305                 310                 315                 320


Ala Ala Val Asn Pro Met Lys Phe Ala Glu Gln Glu Lys Lys Arg Lys 
                325                 330                 335


Met Leu Trp Gln Gly Lys Lys Glu Gly Asp Lys Ser Gln Ser Ala Glu 
            340                 345                 350


Ile Trp Glu Lys Leu Asn Phe Gly Asn Lys Asp Gln Asn Val Lys Phe 
        355                 360                 365


Arg Lys Leu Met Gly Ile Lys Ser Glu Asp Glu Ala Gly Cys Ser Ser 
    370                 375                 380


Val Asp Glu Glu Ser Tyr Lys Thr Leu Lys Gln Gln Glu Glu Val Phe 
385                 390                 395                 400


Arg Asn Leu Asp Ala Gln Tyr Glu Met Ala Arg Ser Gln Thr His Thr 
                405                 410                 415


Gln Arg Gly Met Gly Leu Gly Phe Thr Ser Ser Met Arg Gly Met Asp 
            420                 425                 430


Ala Val 



<210>  8186
<211>  2015
<212>  DNA
<213>  Homo sapiens

<400>  8186
aagctgtgcg acgcgccggg cctcctcgcc tttgtgccat ccgggtctct cgcgcgagcg     60

atttagtctg aggcgaagct tcggagcggc cggtactgtt gaaagcgaca agtggaggcg    120

ccgctctagc ggccgggact ctgaactatg gcggctagtg atacagagcg agatggacta    180

gccccagaaa agacatcacc agatagagat aagaaaaaag agcagtcaga agtatctgtt    240

tctcctagag cttcaaaaca tcattattca agatcacgat caaggtcaag agaaagaaaa    300

cgaaagtcag ataatgaagg aagaaaacac aggagccgga gcagaagcaa agagcgtgct    360

tatgcgcgaa gagactgaac tgaagacgct gcagactcag atagcaaaat aataagccta    420

cttcatgata agggaagaag acatgaatcc aaagataaat cctctaagaa acataagtct    480

gaggaacata atgacaaaga acattcttct gataaaggaa gagagcgact aaattcatct    540

gaaaatggtg aggacaggca caaacgcaaa gaaagaaagt catcaagagg cagaagtcac    600

tcaagatcta ggtctcgtga aagacgccat cgtagtagaa gcagggagcg gaagaagtct    660

cgatccagga gtagggagcg gaagaaatcg agatccagaa gcagagagag gaagaaatcg    720

agatccagaa gcagggaaag aaaacggcgg atcaggtctc gttcccgctc aagatcaaga    780

cacaggcata ggactagaag caggagtagg acaaggagta ggagtcgaga tagaaagaag    840

agaattgaaa agccgagaag atttagcaga agtttaagcc ggactccaag tccacctccc    900

ttcagaggca gaaacacagc aatggatgca caggaagctt tagctagaag gttggaaagg    960

gcaaagaaat tacaagaaca gcgagaaaag gaaatggttg aaaaacaaaa acaacaagaa   1020

atagctgcag ctgcagctac tggaggttct gttctcaatg ttgctgccct gttggcatca   1080

ggaacacaag taacacctca gatagccatg gcagctcaga tggcagccct gcaagctaaa   1140

gctttggcag agacaggaat agctgttcct agctactata acccagccgc tgttaatcca   1200

atgaaatttg ctgaacaaga gaaaaaaagg aaaatgcttt ggcagggcaa gaaagaaggg   1260

gacaaatccc aatctgctga aatatgggaa aaattgaatt ttggaaacaa ggaccaaaat   1320

gtcaaattta ggaaattgat gggtattaag agtgaagatg aagctggatg tagctcagtt   1380

gatgaagaaa gttacaagac tctgaagcag caggaagaag tatttcgaaa tttagatgct   1440

cagtatgaaa tggcaagatc acaaacccac acacaaagag gaatgggttt gggtttcaca   1500

tcttcaatgc gaggaatgga tgcagtttga aaatgatcac acttgtaaag tttgggactt   1560

atagacttct tgttctgatg tcacgtcctt gttcaccaaa cagctagcac tctagcttgc   1620

atgggtgttg cattgacttt aatttattga aaaatacaaa tttttgtaaa tatcagatca   1680

gtgatactgg tgttagtgtt gtaatcaggt taaacccact tccattaaac ttgacaggac   1740

tatagaagga taatattttt tagttcatga attctacttt tcaaatatat aaaagctgca   1800

ggtggggata aaatctcata catggatttt ttcgtgtccg ctgtcttgtg tacttttgta   1860

cttaaccttg tacagttatt ttcatctctt gaaacatgaa agaaatgtta tgtagatgtt   1920

ctttagaaga tctggccatt tggtacataa tccagcacag ataagctggg tggtaatgat   1980

aataaaaatg gttttctcaa aactggtgtt aattt                              2015


<210>  8187
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  8187

Met Asp Ala Gln Glu Ala Leu Ala Arg Arg Leu Glu Arg Ala Lys Lys 
1               5                   10                  15


Leu Gln Glu Gln Arg Glu Lys Glu Met Val Glu Lys Gln Lys Gln Gln 
            20                  25                  30


Glu Ile Ala Ala Ala Ala Ala Thr Gly Gly Ser Val Leu Asn Val Ala 
        35                  40                  45


Ala Leu Leu Ala Ser Gly Thr Gln Val Thr Pro Gln Ile Ala Met Ala 
    50                  55                  60


Ala Gln Met Ala Ala Leu Gln Ala Lys Ala Leu Ala Glu Thr Gly Ile 
65                  70                  75                  80


Ala Val Pro Ser Tyr Tyr Asn Pro Ala Ala Val Asn Pro Met Lys Phe 
                85                  90                  95


Ala Glu Gln Glu Lys Lys Arg Lys Met Leu Trp Gln Gly Lys Lys Glu 
            100                 105                 110


Gly Asp Lys Ser Gln Ser Ala Glu Ile Trp Glu Lys Leu Asn Phe Gly 
        115                 120                 125


Asn Lys Asp Gln Asn Val Lys Phe Arg Lys Leu Met Gly Ile Lys Ser 
    130                 135                 140


Glu Asp Glu Ala Gly Cys Ser Ser Val Asp Glu Glu Ser Tyr Lys Thr 
145                 150                 155                 160


Leu Lys Gln Gln Glu Glu Val Phe Arg Asn Leu Asp Ala Gln Tyr Glu 
                165                 170                 175


Met Ala Arg Ser Gln Thr His Thr Gln Arg Gly Met Gly Leu Gly Phe 
            180                 185                 190


Thr Ser Ser Met Arg Gly Met Asp Ala Val 
        195                 200


<210>  8188
<211>  1948
<212>  DNA
<213>  Homo sapiens

<400>  8188
tttctcccag caagctgtgc gacgcgccgg gcctcctcgc ctttgtgcca tccgggtctc     60

tcgcgcgagc gatttagtct gaggcgaagc ttcggagcgg ccggtactgt tgaaagcgac    120

aagtggaggc gccgctctag cggccgggac tctgaactat ggcggctagt gatacagagc    180

gagatggact agccccagaa aagacatcac cagatagaga taagaaaaaa gagcagtcag    240

aagtatctgt ttctcctaga gcttcaaaac atcattattc aagatcacga tcaaggtcaa    300

gagaaagaaa acgaaagtca gataatgaag gaagaaaaca caggagccgg agcagaagca    360

aagagggaag aagacatgaa tccaaagata aatcctctaa gaaacataag tctgaggaac    420

ataatgacaa agaacattct tctgataaag gaagagagcg actaaattca tctgaaaatg    480

gtgaggacag gcacaaacgc aaagaaagaa agtcatcaag aggcagaagt cactcaagat    540

ctaggtctcg tgaaagacgc catcgtagta gaagcaggga gcggaagaag tctcgatcca    600

ggagtaggga gcggaagaaa tcgagatcca gaagcagaga gaggaagaaa tcgagatcca    660

gaagcaggga aagaaaacgg cggatcaggt ctcgttcccg ctcaagatca agacacaggc    720

ataggactag aagcaggagt aggacaagga gtaggagtcg agatagaaag aagagaattg    780

aaaagccgag aagatttagc agaagtttaa gccggactcc aagtccacct cccttcagag    840

gcagaaacac agcaatggat gcacaggaag ctttagctag aaggttggaa agggcaaaga    900

aattacaaga acagcgagaa aaggaaatgg ttgaaaaaca aaaacaacaa gaaatagctg    960

cagctgcagc tactggaggt tctgttctca atgttgctgc cctgttggca tcaggaacac   1020

aagtaacacc tcagatagcc atggcagctc agatggcagc cctgcaagct aaagctttgg   1080

cagagacagg aatagctgtt cctagctact ataacccagc cgctgttaat ccaatgaaat   1140

ttgctgaaca agagaaaaaa aggaaaatgc tttggcaggg caagaaagaa ggggacaaat   1200

cccaatctgc tgaaatatgg gaaaaattga attttggaaa caaggaccaa aatgtcaaat   1260

ttaggaaatt gatgggtatt aagagtgaag atgaagctgg atgtagctca gttgatgaag   1320

aaagttacaa gactctgaag cagcaggaag aagtatttcg aaatttagat gctcagtatg   1380

aaatggcaag atcacaaacc cacacacaaa gaggaatggg tttgggtttc acatcttcaa   1440

tgcgaggaat ggatgcagtt tgaaaatgat cacacttgta aagtttggga cttatagact   1500

tcttgttctg atgtcacgtc cttgttcacc aaacagctag cactctagct tgcatgggtg   1560

ttgcattgac tttaatttat tgaaaaatac aaatttttgt aaatatcaga tcagtgatac   1620

tggtgttagt gttgtaatca ggttaaaccc acttccatta aacttgacag gactatagaa   1680

ggataatatt ttttagttca tgaattctac ttttcaaata tataaaagct gcaggtgggg   1740

ataaaatctc atacatggat tttttcgtgt ccgctgtctt gtgtactttt gtacttaacc   1800

ttgtacagtt attttcatct cttgaaacat gaaagaaatg ttatgtagat gttctttaga   1860

agatctggcc atttggtaca taatccagca cagataagct gggtggtaat gataataaaa   1920

atggttttct caaaactggt gttaattt                                      1948


<210>  8189
<211>  434
<212>  PRT
<213>  Homo sapiens

<400>  8189

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Gly Arg Arg His Glu Ser Lys Asp Lys Ser Ser 
65                  70                  75                  80


Lys Lys His Lys Ser Glu Glu His Asn Asp Lys Glu His Ser Ser Asp 
                85                  90                  95


Lys Gly Arg Glu Arg Leu Asn Ser Ser Glu Asn Gly Glu Asp Arg His 
            100                 105                 110


Lys Arg Lys Glu Arg Lys Ser Ser Arg Gly Arg Ser His Ser Arg Ser 
        115                 120                 125


Arg Ser Arg Glu Arg Arg His Arg Ser Arg Ser Arg Glu Arg Lys Lys 
    130                 135                 140


Ser Arg Ser Arg Ser Arg Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg 
145                 150                 155                 160


Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg Glu Arg Lys Arg Arg Ile 
                165                 170                 175


Arg Ser Arg Ser Arg Ser Arg Ser Arg His Arg His Arg Thr Arg Ser 
            180                 185                 190


Arg Ser Arg Thr Arg Ser Arg Ser Arg Asp Arg Lys Lys Arg Ile Glu 
        195                 200                 205


Lys Pro Arg Arg Phe Ser Arg Ser Leu Ser Arg Thr Pro Ser Pro Pro 
    210                 215                 220


Pro Phe Arg Gly Arg Asn Thr Ala Met Asp Ala Gln Glu Ala Leu Ala 
225                 230                 235                 240


Arg Arg Leu Glu Arg Ala Lys Lys Leu Gln Glu Gln Arg Glu Lys Glu 
                245                 250                 255


Met Val Glu Lys Gln Lys Gln Gln Glu Ile Ala Ala Ala Ala Ala Thr 
            260                 265                 270


Gly Gly Ser Val Leu Asn Val Ala Ala Leu Leu Ala Ser Gly Thr Gln 
        275                 280                 285


Val Thr Pro Gln Ile Ala Met Ala Ala Gln Met Ala Ala Leu Gln Ala 
    290                 295                 300


Lys Ala Leu Ala Glu Thr Gly Ile Ala Val Pro Ser Tyr Tyr Asn Pro 
305                 310                 315                 320


Ala Ala Val Asn Pro Met Lys Phe Ala Glu Gln Glu Lys Lys Arg Lys 
                325                 330                 335


Met Leu Trp Gln Gly Lys Lys Glu Gly Asp Lys Ser Gln Ser Ala Glu 
            340                 345                 350


Ile Trp Glu Lys Leu Asn Phe Gly Asn Lys Asp Gln Asn Val Lys Phe 
        355                 360                 365


Arg Lys Leu Met Gly Ile Lys Ser Glu Asp Glu Ala Gly Cys Ser Ser 
    370                 375                 380


Val Asp Glu Glu Ser Tyr Lys Thr Leu Lys Gln Gln Glu Glu Val Phe 
385                 390                 395                 400


Arg Asn Leu Asp Ala Gln Tyr Glu Met Ala Arg Ser Gln Thr His Thr 
                405                 410                 415


Gln Arg Gly Met Gly Leu Gly Phe Thr Ser Ser Met Arg Gly Met Asp 
            420                 425                 430


Ala Val 



<210>  8190
<211>  1385
<212>  DNA
<213>  Homo sapiens

<400>  8190
gcagctgcag ctactggagg ttctgttctc aatgttgctg ccctgttggc atcaggaaca     60

caagtaacac ctcagatagc catggcagct cagatggcag ccctgcaagc taaagctttg    120

gcagagacag gaatagctgt tcctagctac tataacccag ccgctgttaa tccaatgaaa    180

tttgctgaac aagagaaaaa aaggaaaatg ctttggcagg gcaagaaaga aggggtaagt    240

tctcttattc tgcttttctg tcgtttattc ctaattagta attgcttaga aaaacaaatt    300

tgggttgaaa aatattactt tcggcttaac tttgtaagaa cctggggtgg ccagacgcgg    360

gtggcttatg cctttaatcc cagcactttg ggatgccaag tgagcggatc agttgaggta    420

aggagtccaa gaccagcctg gccaacatgg caaaaccctg tctctactga aaagaagata    480

aaaatcagct gggtgtggtg gcacacacct gtaatcccag gtgcttggga ggctgaggca    540

ggagaatcgc ttgagcctgg gatgcagagc ctacatacag tgcccaccac catgccaggc    600

tagttttttg tatttttagt agagacgggg tttcacctag tcatccaggc tagtctcgat    660

cccctgacct caggtgattt gcccacctcg gccttccaaa gtgctgggat tataggagtg    720

aagcacggcg ccaacctctt gcttgtattt ctttgctttg tggtttctta agtcttgaaa    780

taattaaact tacattgatt gaatgctatc catggtgttt ttttttttaa tttagacatt    840

gttgagagat ttcatgtcct aaaaaatatt taaattttac atattttaaa gttcagtgtt    900

tgttaacagg acaaatccca atctgctgaa atatgggaaa aattgaattt tggaaacaag    960

gaccaaaatg tcaaatttag gaaattgatg ggtattaagg tgagtttcac atgtgccagg   1020

ggatctttgt attagctatt agccctcctg cactgttctt ccctcatttt cttagttctg   1080

gtctttactc aggtgtcagc gtttttgagt tctttcccac caccttttgt gaaataacaa   1140

gcaatcccat tctgaaacat ttccatctcc cctacccact gtcctcccta cacacacact   1200

tggagagaga gagagagacg gggttttgct ctgcttgctc tgtcacttgg gctggagtac   1260

agtggtgcag tcatacctca ctgcagcctt aaacttcgag gctcaagcag tccttccacc   1320

tcggcctctc aaagccctgg atcacagttc tgagccactg cgcccagcct ccatccccat   1380

tttct                                                               1385


<210>  8191
<211>  173
<212>  PRT
<213>  Homo sapiens

<400>  8191

Met Ala Ala Gln Met Ala Ala Leu Gln Ala Lys Ala Leu Ala Glu Thr 
1               5                   10                  15


Gly Ile Ala Val Pro Ser Tyr Tyr Asn Pro Ala Ala Val Asn Pro Met 
            20                  25                  30


Lys Phe Ala Glu Gln Glu Lys Lys Arg Lys Met Leu Trp Gln Gly Lys 
        35                  40                  45


Lys Glu Gly Val Ser Ser Leu Ile Leu Leu Phe Cys Arg Leu Phe Leu 
    50                  55                  60


Ile Ser Asn Cys Leu Glu Lys Gln Ile Trp Val Glu Lys Tyr Tyr Phe 
65                  70                  75                  80


Arg Leu Asn Phe Val Arg Thr Trp Gly Gly Gln Thr Arg Val Ala Tyr 
                85                  90                  95


Ala Phe Asn Pro Ser Thr Leu Gly Cys Gln Val Ser Gly Ser Val Glu 
            100                 105                 110


Val Arg Ser Pro Arg Pro Ala Trp Pro Thr Trp Gln Asn Pro Val Ser 
        115                 120                 125


Thr Glu Lys Lys Ile Lys Ile Ser Trp Val Trp Trp His Thr Pro Val 
    130                 135                 140


Ile Pro Gly Ala Trp Glu Ala Glu Ala Gly Glu Ser Leu Glu Pro Gly 
145                 150                 155                 160


Met Gln Ser Leu His Thr Val Pro Thr Thr Met Pro Gly 
                165                 170


<210>  8192
<211>  1024
<212>  DNA
<213>  Homo sapiens

<400>  8192
ccgggtctct cgcgcgagcg atttagtctg aggcgaagct tcggagcggc cggtactgtt     60

gaaagcgaca agtggaggcg ccgctctagc ggccgggact ctgaactatg gcgataatga    120

aggaagaaaa cacaggagcc ggagcagaag caaagagcgt gcttatgcgc gaagagactg    180

aactgaagac gctgcagact cagatagcaa aataataagc ctacttcatg ataagggaag    240

aagacatgaa tccaaagata aatcctctaa gaaacataag tctgaggaac ataatgacaa    300

agaacattct tctgataaag gaagagagcg actaaattca tctgaaaatg gtgaggacag    360

gcacaaacgc aaagaaagaa agtcatcaag aggcagaagt cactcaagat ctaggtctcg    420

tgaaagacgc catcgtagta gaagcaggga gcggaagaag tctcgatcca ggagtaggga    480

gcggaagaaa tcgagatcca gaagcagaga gaggaagaaa tcgagatcca gaagcaggga    540

aagaaaacgg cggatcaggt ctcgttcccg ctcaagatca agacacaggc ataggactag    600

aagcaggagt aggacaagga gtaggagtcg agatagaaag aagagaattg aaaagccgag    660

aagatttagc agaagtttaa gccggactcc aagtccacct cccttcagag gcagaaacac    720

agcaatggat gcacaggaag ctttagctag aaggttggaa agggcaaaga aattacaaga    780

acagcgagaa aaggaaatgg ttgaaaaaca aaaacaacaa gaaatagctg cagctgcagc    840

tactggaggt tctgttctca atgttgctgc cctgttggca tcaggaacac aagtaacacc    900

tcagatagcc atggcagctc agatggcagc cctgcaagct aaagctttgg cagagacagg    960

aatagctgtt cctagctact ataacccagc cgctgttaat ccaatgaaat ttgctgaaca   1020

agag                                                                1024


<210>  8193
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  8193

Met Val Arg Thr Gly Thr Asn Ala Lys Lys Glu Ser His Gln Glu Ala 
1               5                   10                  15


Glu Val Thr Gln Asp Leu Gly Leu Val Lys Asp Ala Ile Val Val Glu 
            20                  25                  30


Ala Gly Ser Gly Arg Ser Leu Asp Pro Gly Val Gly Ser Gly Arg Asn 
        35                  40                  45


Arg Asp Pro Glu Ala Glu Arg Gly Arg Asn Arg Asp Pro Glu Ala Gly 
    50                  55                  60


Lys Glu Asn Gly Gly Ser Gly Leu Val Pro Ala Gln Asp Gln Asp Thr 
65                  70                  75                  80


Gly Ile Gly Leu Glu Ala Gly Val Gly Gln Gly Val Gly Val Glu Ile 
                85                  90                  95


Glu Arg Arg Glu Leu Lys Ser Arg Glu Asp Leu Ala Glu Val 
            100                 105                 110


<210>  8194
<211>  1154
<212>  DNA
<213>  Homo sapiens

<400>  8194
tttctcccag caagctgtgc gacgcgccgg gcctcctcgc ctttgtgcca tccgggtctc     60

tcgcgcgagc gatttagtct gaggcgaagc ttcggagcgg ccggtactgt tgaaagcgac    120

aagtggaggc gccgctctag cggccgggac tctgaactat ggcggctagt gatacagagc    180

gagatggact agccccagaa aagacatcac cagatagaga taagaaaaaa gagcagtcag    240

aagtatctgt ttctcctaga gcttcaaaac atcattattc aagatcacga tcaaggtcaa    300

gagaaagaaa acgaaagtca gataatgaag gaagaaaaca caggagccgg agcagaagca    360

aagagggaag aagacatgaa tccaaagata aatcctctaa gaaacataag tctgaggaac    420

ataatgacaa agaacattct tctgataaag gaagagagcg actaaattca tctgaaaatg    480

gtgaggacag gcacaaacgc aaagaaagaa agtcatcaag aggcagaagt cactcaagat    540

ctaggtctcg tgaaagacgc catcgtagta gaagcaggga gcggaagaag tctcgatcca    600

ggagtaggga gcggaagaaa tcgagatcca gaagcagaga gaggaagaaa tcgagatcca    660

gaagcaggga aagaaaacgg cggatcaggt ctcgttcccg ctcaagatca agacacaggc    720

ataggactag aagcaggagt aggacaagga gtaggagtcg agatagaaag aagagaattg    780

aaaagccgag aagatttagc agaagtttaa gccggactcc aagtccacct cccttcagag    840

gcagaaacac agcaatggat gcacaggaag ctttagctag aaggttggaa agggcaaaga    900

aattacaaga acagcgagaa aaggaaatgg ttgaaaaaca aaaacaacaa gaaatagctg    960

cagctgcagc tactggaggt tctgttctca atgttgctgc cctgttggca tcaggaacac   1020

aagtaacacc tcagatagcc atggcagctc agatggcagc cctgcaagct aaagctttgg   1080

cagagacagg aatagctgtt cctagctact ataacccagc cgctgttaat ccaatgaaat   1140

ttgctgaaca agag                                                     1154


<210>  8195
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  8195

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Gly Arg Arg His Glu Ser Lys Asp Lys Ser Ser 
65                  70                  75                  80


Lys Lys His Lys Ser Glu Glu His Asn Asp Lys Glu His Ser Ser Asp 
                85                  90                  95


Lys Gly Arg Glu Arg Leu Asn Ser Ser Glu Asn Gly Glu Asp Arg His 
            100                 105                 110


Lys Arg Lys Glu Arg Lys Ser Ser Arg Gly Arg Ser His Ser Arg Ser 
        115                 120                 125


Arg Ser Arg Glu Arg Arg His Arg Ser Arg Ser Arg Glu Arg Lys Lys 
    130                 135                 140


Ser Arg Ser Arg Ser Arg Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg 
145                 150                 155                 160


Glu Arg Lys Lys Ser Arg Ser Arg Ser Arg Glu Arg Lys Arg Arg Ile 
                165                 170                 175


Arg Ser Arg Ser Arg Ser Arg Ser Arg His Arg His Arg Thr Arg Ser 
            180                 185                 190


Arg Ser Arg Thr Arg Ser Arg Ser Arg Asp Arg Lys Lys Arg Ile Glu 
        195                 200                 205


Lys Pro Arg Arg Phe Ser Arg Ser Leu Ser Arg Thr Pro Ser Pro Pro 
    210                 215                 220


Pro Phe Arg Gly Arg Asn Thr Ala Met Asp Ala Gln Glu Ala Leu Ala 
225                 230                 235                 240


Arg Arg Leu Glu Arg Ala Lys Lys Leu Gln Glu Gln Arg Glu Lys Glu 
                245                 250                 255


Met Val Glu Lys Gln Lys Gln Gln Glu Ile Ala Ala Ala Ala Ala Thr 
            260                 265                 270


Gly Gly Ser Val Leu Asn Val Ala Ala Leu Leu Ala Ser Gly Thr Gln 
        275                 280                 285


Val Thr Pro Gln Ile Ala Met Ala Ala Gln Met Ala Ala Leu Gln Ala 
    290                 295                 300


Lys Ala Leu Ala Glu Thr Gly Ile Ala Val Pro Ser Tyr Tyr Asn Pro 
305                 310                 315                 320


Ala Ala Val Asn Pro Met Lys Phe Ala Glu Gln 
                325                 330


<210>  8196
<211>  2070
<212>  DNA
<213>  Homo sapiens

<400>  8196
gcctttgtgc catccgggtc tctcgcgcga gcgatttagt ctgaggcgaa gcttcggagc     60

ggccggtact gttgaaagcg acaagtggag gcgccgctct agcggccggg actctgaact    120

atggcggcta gtgatacaga gcgagatgga ctagccccag aaaagacatc accagataga    180

gataagaaaa aagagcagtc agaagtatct gtttctccta gagcttcaaa acatcattat    240

tcaagatcac gatcaaggtc aagagaaaga aaacgaaagt cagataatga aggaagaaaa    300

cacaggagcc ggagcagaag caaagagcgt gcttatgcgc gaagagactg aactgaagac    360

gctgcagact cagatagcaa aataataagc ctacttcatg ataaggtaac tattagtcat    420

tcaaactcct atttccctta aatatatctt aaatcagtta agggttttaa tgtttttttt    480

aaattaatag taatgttatg tttgaaaaac tggtttgaaa taaactttaa aacctttaga    540

agtttaacca cttaagactt ttccagtctg cctcgttata gcaaaaccaa ggaaaatttc    600

ttttctaagc tcctatagag aactggcaat gaaactaaaa tttaattgtg tctccaggtc    660

tcttattttt ctgcaaataa taaattatgt actatgatca ttttcagata aatcatcatg    720

catgttccaa aatgattggc caagttttat ttttaagaaa cattaatcgt gagtggaaag    780

aaacatgcta tggccttttg ggagacagta gtgtcttatt acagtggaaa agtggtagcg    840

tgggcatcag aaaaacatgg ggaaggttca gctcacccat gtagctttgt aactttagat    900

cttagttata cataaaataa ggggattaag ttagaggatc ttagtttcct tccagaatta    960

aaatttagtg attcagagat gtctaggatt ttaaactttc actacaagat gaatttgaca   1020

gatcttcctg tagggaactg tagtatgtag cacttctact ttggtatttg gtaggatgag   1080

acttgatcat gcagttaatt tgagctgagt ctctgaatgc acatgtgaag gccttggtct   1140

ttttaaagtg tgggggcagt atgtattgtg tgatggcatg tggattgtta tacctagttt   1200

ggtttcttta aaattgaaac atacagttgc catttctacc ctaggtacat gaagtgtaat   1260

actcctctaa gcctattggg atactgcaag atgaaaagtg attgcttcac agtttagaca   1320

ttgggaggaa aatcaagagc tgtcttttag aggatgtagc aggcagtata actgtaaaag   1380

ggacactgca tctctgtgta aaataatttg aaattataga aaatattagt acttagtaat   1440

aattatattt agctacctaa ttgaaatgcg tttctggtgc actttttgtg tcattatctc   1500

cattacttac ttaaacttaa cattatgtaa tctggattta gaagttgatg tatatacatg   1560

gtctgtattc ttttagataa acataaggga ttcctctttt gtctggcata atggcttttc   1620

aatatttcaa ctttaaaaat cattgtttct gttgtattga aaatattttg gggaggaact   1680

acattttggg tgtttatagt aaaaaaaata gtaattacat ctgcaacatt tgggtgatgt   1740

gaaactagat ctttttttta tttgccacac actcctaagg ttactaatgt tgcatcacaa   1800

catttttgtc tactgatacc catactaact ctctttgttg cactattttc ctgaaagaac   1860

caacttcttc ttaaaacagg gaagaagaca tgaatccaaa gataaatcct ctaagaaaca   1920

taagtctgag gaacataatg acaaagaaca ttcttctgat aaaggaagag agcgactaaa   1980

ttcatctgaa aatggtgagg acaggcacaa acgcaaagaa agaaagtcat caagaggcag   2040

aagtcactca agatctaggt ctcgtgaaag                                    2070


<210>  8197
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  8197

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Arg Ala Tyr Ala Arg Arg Asp 
65                  70                  75


<210>  8198
<211>  2887
<212>  DNA
<213>  Homo sapiens

<400>  8198
cgccgggcct cctcgccttt gtgccatccg ggtctctcgc gcgagcgatt tagtctgagg     60

cgaagcttcg gagcggccgg tactgttgaa agcgacaagt ggaggcgccg ctctagcggc    120

cgggactctg aactatggcg gctagtgata cagagcgaga tggactagcc ccagaaaaga    180

catcaccaga tagagataag aaaaaagagc agtcagaagt atctgtttct cctagagctt    240

caaaacatca ttattcaaga tcacgatcaa ggtcaagaga aagaaaacga aagtcagata    300

atgaaggaag aaaacacagg agccggagca gaagcaaaga ggtaattaac actttgtagt    360

gaataggtac tttaaaatac ttataaagtg tctggtagaa agatttgtat gaatataaga    420

cgttgtcaag gtaagtacaa aacttgaaat ttaaaaggtt tattgggtta taaaataagc    480

atgattttga ttcatcattt ttgaagaaga tgtttatgtg aaaagtacct tcaaaacttt    540

aattttatta tattgtgaaa atattcacaa taaaaatttc atatgaagaa tatgattggt    600

ttttttaggc ctgtcacaca gagcttccat taatctgagg tcccgagtct cctggtgcct    660

gacagttgct caggattttt aaacagcaat catctttaca tagcaatacc ctagatatct    720

gtgcgctgct ttttccttat gaacgataac aggagttctc ttttcttttg caaactagtt    780

cagtttccct aatagtagta ttgaattttg aaataaaggt ttgagtgagg gacagctgaa    840

aaggtggcgg tgacaccaaa acttgaggaa aaagaaaggc agcagctgta ttgcaaagga    900

gttacttgtt cacccacctg agaagacaaa gaatgagcca ataaggaagt gtagaagtag    960

tagccagaaa gggagaagag tcttgtgggg gctgggtaag ggactcctaa aacaagagtg   1020

ggcagggact tcacctcttc ccgtaatgga agctctgtta aatttttaat ttaggagagt   1080

ttttgtgaaa atgactattt tgtttagctc acatgataac atttctataa taaatcatac   1140

tcagcgtgct tatgcgcgaa gagactgaac tgaagacgct gcagactcag atagcaaaat   1200

aataagccta cttcatgata aggtaactat tagtcattca aactcctatt tcccttaaat   1260

atatcttaaa tcagttaagg gttttaatgt tttttttaaa ttaatagtaa tgttatgttt   1320

gaaaaactgg tttgaaataa actttaaaac ctttagaagt ttaaccactt aagacttttc   1380

cagtctgcct cgttatagca aaaccaagga aaatttcttt tctaagctcc tatagagaac   1440

tggcaatgaa actaaaattt aattgtgtct ccaggtctct tatttttctg caaataataa   1500

attatgtact atgatcattt tcagataaat catcatgcat gttccaaaat gattggccaa   1560

gttttatttt taagaaacat taatcgtgag tggaaagaaa catgctatgg ccttttggga   1620

gacagtagtg tcttattaca gtggaaaagt ggtagcgtgg gcatcagaaa aacatgggga   1680

aggttcagct cacccatgta gctttgtaac tttagatctt agttatacat aaaataaggg   1740

gattaagtta gaggatctta gtttccttcc agaattaaaa tttagtgatt cagagatgtc   1800

taggatttta aactttcact acaagatgaa tttgacagat cttcctgtag ggaactgtag   1860

tatgtagcac ttctactttg gtatttggta ggatgagact tgatcatgca gttaatttga   1920

gctgagtctc tgaatgcaca tgtgaaggcc ttggtctttt taaagtgtgg gggcagtatg   1980

tattgtgtga tggcatgtgg attgttatac ctagtttggt ttctttaaaa ttgaaacata   2040

cagttgccat ttctacccta ggtacatgaa gtgtaatact cctctaagcc tattgggata   2100

ctgcaagatg aaaagtgatt gcttcacagt ttagacattg ggaggaaaat caagagctgt   2160

cttttagagg atgtagcagg cagtataact gtaaaaggga cactgcatct ctgtgtaaaa   2220

taatttgaaa ttatagaaaa tattagtact tagtaataat tatatttagc tacctaattg   2280

aaatgcgttt ctggtgcact ttttgtgtca ttatctccat tacttactta aacttaacat   2340

tatgtaatct ggatttagaa gttgatgtat atacatggtc tgtattcttt tagataaaca   2400

taagggattc ctcttttgtc tggcataatg gcttttcaat atttcaactt taaaaatcat   2460

tgtttctgtt gtattgaaaa tattttgggg aggaactaca ttttgggtgt ttatagtaaa   2520

aaaaatagta attacatctg caacatttgg gtgatgtgaa actagatctt ttttttattt   2580

gccacacact cctaaggtta ctaatgttgc atcacaacat ttttgtctac tgatacccat   2640

actaactctc tttgttgcac tattttcctg aaagaaccaa cttcttctta aaacagggaa   2700

gaagacatga atccaaagat aaatcctcta agaaacataa gtctgaggaa cataatgaca   2760

aagaacattc ttctgataaa ggaagagagc gactaaattc atctgaaaat ggtgaggaca   2820

ggcacaaacg caaagaaaga aagtcatcaa gaggcagaag tcactcaaga tctaggtctc   2880

gtgaaag                                                             2887


<210>  8199
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  8199

Met Ala Ala Ser Asp Thr Glu Arg Asp Gly Leu Ala Pro Glu Lys Thr 
1               5                   10                  15


Ser Pro Asp Arg Asp Lys Lys Lys Glu Gln Ser Glu Val Ser Val Ser 
            20                  25                  30


Pro Arg Ala Ser Lys His His Tyr Ser Arg Ser Arg Ser Arg Ser Arg 
        35                  40                  45


Glu Arg Lys Arg Lys Ser Asp Asn Glu Gly Arg Lys His Arg Ser Arg 
    50                  55                  60


Ser Arg Ser Lys Glu Val Ile Asn Thr Leu 
65                  70


<210>  8200
<211>  553
<212>  DNA
<213>  Homo sapiens

<400>  8200
gcgcgagcga tttagtctga ggcgaagctt cggagcggcc ggtactgttg aaagcgacaa     60

gtggaggcgc cgctctagcg gccgggactc tgaactatgg cgataatgaa ggaagaaaac    120

acaggagccg gagcagaagc aaagaggtaa ttaacacttt gtagtgaata ggtactttaa    180

aatacttata aagtgtctgg tagaaagatt tgtatgaata taagacgttg tcaaggtaag    240

tacaaaactt gaaatttaaa aggtttattg ggttataaaa taagcatgat tttgattcat    300

catttttgaa gaagatgttt atgtgaaaag taccttcaaa actttaattt tattatattg    360

tgaaaatatt cacaataaaa atttcatatg aagaatatga ttggtttttt taggcctgtc    420

acacagagct tccattaatc tgaggtcccg agtctcctgg tgcctgacag ttgctcagga    480

tttttaaaca gcaatcatct ttacatagca ataccctaga tatctgtgcg ctgctttttc    540

cttatgaacg ata                                                       553


<210>  8201
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  8201

Gly Glu Ala Ser Glu Arg Pro Val Leu Leu Lys Ala Thr Ser Gly Gly 
1               5                   10                  15


Ala Ala Leu Ala Ala Gly Thr Leu Asn Tyr Gly Asp Asn Glu Gly Arg 
            20                  25                  30


Lys His Arg Ser Arg Ser Arg Ser Lys Glu Val Ile Asn Thr Leu 
        35                  40                  45


<210>  8202
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  8202
acaaagctgg acaacagaga aacctccctg tgacataggc taacttaaac ttacatcatc     60

aaccattttc atctgtaaaa tatactacag agcaacaaca aaaaccatct taacactaaa    120

caaataggaa tgataggtgg tcattgaggc catggaaaac ttttatttcc ctgaggatat    180

tttatagtag cataatacag gtatccagga aaaaaaccta ccaaaaactg agtattaaaa    240

ttgctctgaa attttctaag ctttaattta gtactaatct atgtgtacac ataaacgtta    300

actgcaaaac agccttctat tccagcagtg gctctacgag gtagccactt tggtttctta    360

taatttacat tttgttgcaa actctaataa cggctcgaaa catagacaaa tctttttcca    420

ctgcgaagga ggtaagcact ggattgaata ctaggtcact tctctagggg actgtctttt    480

tattgaacaa ggcacggcat aaataaatgt ttaaattcac tttttaaaat actagaaccc    540

gggtttaaat ttaaaggaac aaggtcagtg acaagactta actgtaacgc ttctcggact    600

tcaaattgat tacatcacgg gccacttcgg aaaccgcgca tcagtcagaa ttggtag       657


<210>  8203
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  8203

Thr Arg His Gly Ile Asn Lys Cys Leu Asn Ser Leu Phe Lys Ile Leu 
1               5                   10                  15


Glu Pro Gly Phe Lys Phe Lys Gly Thr Arg Ser Val Thr Arg Leu Asn 
            20                  25                  30


Cys Asn Ala Ser Arg Thr Ser Asn 
        35                  40


<210>  8204
<211>  506
<212>  DNA
<213>  Homo sapiens

<400>  8204
gggtatctta tacacacgca ggcttattgt tcagaataga taatttacga actgtagctc     60

ctctggggcc aacgaagggt ttaaatttaa aggaacaagg tcagtgacaa gacttaactg    120

taacgcttct cggacttcaa attgattaca tcacgggcca cttcggaaac cgcgcatcag    180

tcagaattgg tagttccaca accttttaag ttgaattttc actccctttc agcaatacct    240

tcctagctcg ttaatacaca ataataaggt ttacacggac gaacactaat tgaaattatg    300

caactagaag catctcattg agcgtacaaa aaaaaaaata gctacaagtc gctctcttct    360

cccacactac cctttacaga cactgccttt ttgacccaat acttttcaga gaccactcct    420

gatcgtcttt ctcttcccca gcccctttct ccaccgcaaa ttctcaggcc ctaaaaaaaa    480

cttagaataa atcactagcc agggtg                                         506


<210>  8205
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  8205

Val Ser Tyr Thr His Ala Gly Leu Leu Phe Arg Ile Asp Asn Leu Arg 
1               5                   10                  15


Thr Val Ala Pro Leu Gly Pro Thr Lys Gly Leu Asn Leu Lys Glu Gln 
            20                  25                  30


Gly Gln 



<210>  8206
<211>  330
<212>  DNA
<213>  Homo sapiens

<400>  8206
gccaatttaa gcctgtggca tggaacctaa agactagagg cggttgtgtg agtcaggaag     60

aggggccaga tatctgagtg ttcctcttta gtttcttcaa ttgcaggaga gaggttggag    120

tcggtttttg ctggcggcga tgtccagcgg agagcgttta agtatggagg cctaactgac    180

aagtgtttca tcttgctcat tctctcgtat tcgcgaatct gttctgcatt ccgccgccag    240

agtgatctca aaattataaa atcagaccac tcgtttgctg agttcccctt ctaccccttg    300

tactgagaat aaaattcaat cttgaggtcg                                     330


<210>  8207
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  8207

Val Arg Lys Arg Gly Gln Ile Ser Glu Cys Ser Ser Leu Val Ser Ser 
1               5                   10                  15


Ile Ala Gly Glu Arg Leu Glu Ser Val Phe Ala Gly Gly Asp Val Gln 
            20                  25                  30


Arg Arg Ala Phe Lys Tyr Gly Gly Leu Thr Asp Lys Cys Phe Ile Leu 
        35                  40                  45


Leu Ile Leu Ser Tyr Ser Arg Ile Cys Ser Ala Phe Arg Arg Gln Ser 
    50                  55                  60


Asp Leu Lys Ile Ile Lys Ser Asp His Ser Phe Ala Glu Phe Pro Phe 
65                  70                  75                  80


Tyr Pro Leu Tyr 



<210>  8208
<211>  6947
<212>  DNA
<213>  Homo sapiens

<400>  8208
caatttaagc ctgtggcatg gaacctaaag actagaggcg gttgtgtgag tcaggaagag     60

gggccagata tctgagtgtt cctctttagt ttcttcaatt gcaggaaaga cagtggttcc    120

tgactcagga agacagtctc agaaacatgt ggaatgatat tgagctgcta acaaatgatg    180

ataccggaag tgggtacctg agtgtcggtt caagaaaaga acatggaact gctttatatc    240

aagtagattt gctagtgaag atctcttctg aaaaggcctc attaaatcca aagatacagg    300

catgcagctt aagtgatggg tttattattg tagccgacca atcagtgata ttgcttgaca    360

gtatttgtag atcacttcaa ttgcatcttg tctttgatac tgaagtggat gtagttggcc    420

tttgtcaaga aggaaagttt cttttggttg gcgagagaag tggcaaccta catcttattc    480

atgtaacatc aaaacaaaca ctactcacta atgcatttgt tcagaaagct aacgatgaaa    540

atcggcggac ttaccagaat cttgtcattg agaaggatgg ttcaaatgaa ggtacctatt    600

atatgctact tcttacatac agtggatttt tttgtattac aaaccttcag cttttaaaaa    660

ttcaacaagc aattgagaat gtagacttca gtacagcaaa aaagttacaa ggacaaatca    720

agtccagttt tatttctact gaaaattatc atactcttgg ttgtctcagt cttgtggctg    780

gagatttagc aagtgaagtt cctgtgataa ttgggggaac cggtaattgt gcattctcaa    840

aatgggaacc agattcttcc aagaaaggaa tgacagttaa gaaccttatt gatgcagaga    900

ttattaaagg tgcaaagaag ttccagctga tagacaatct actttttgtt cttgatactg    960

ataacgtgct gagtttatgg gatatttaca ctctaactcc tgtatggaac tggccctctc   1020

ttcacgtaga agagtttctt cttactacag aagcagactc tccttcatca gtcacgtggc   1080

aaggaattac aaatctcaaa ttaatagctc tgacagcttc agctaataag aagatgaaaa   1140

acctcatggt ttattcatta cctacaatgg aaatactata ttctttggaa gtatctagtg   1200

tttcttctct ggtccaaaca ggaattagca cagataccat atacctttta gaaggagttt   1260

gcaaaaatga tccaaaattg tctgaagact cagtctctgt gttagtactc agatgtctta   1320

cggaagcttt accagaaaac agattgagtc ggttacttca caaacacaga tttgctgaag   1380

ctgagagttt tgccattcag tttggactag atgttgagct tgtttacaag gtcaagtcaa   1440

atcatatatt ggagaaactg gcattgagtt ctgtggatgc cagtgaacag accgaatggc   1500

aacaacttgt agacgacgct aaggaaaatc tacataagat ccaggatgat gaatttgtgg   1560

tgaattactg cctgaaagct cagtggataa cctatgaaac cactcaagag atgctgaatt   1620

atgccaaaac caggcttttg aagaaagaag ataaaactgc tctcatttat tctgatggct   1680

tgaaagaggt gctaagagct catgcaaaat tgactacttt ttatggagca tttggaccag   1740

aaaaattcag tggcagttct tggattgaat ttctaaataa tgaagatgat cttaaagata   1800

tttttttaca gctaaaagaa ggaaaccttg tttgtgcaca gtatctttgg cttcgacatc   1860

gggcaaactt tgaaagcaga tttgatgtga aaatgctgga gagcttgctc aactcaatgt   1920

ctgcatcagt ctctttgcaa aagctgtgtc catggtttaa aaatgatgtg attccatttg   1980

taagaaggac tgtgcctgaa ggacagataa ttcttgcaaa atggttggaa caagcagcca   2040

ggaaccttga attaactgat aaggcaaatt ggccagaaaa tggacttcaa ttggcagaga   2100

tattttttac agcagaaaaa acagacgagt tgggattggc atcttcctgg cattggattt   2160

ccttgaaaga ttatcagaac acagaggaag tatgtcagct aaggactttg gtaaataact   2220

tgcgagagtt gatcacgttg cataggaagt acaactgcaa attagccctc tctgattttg   2280

agaaggaaaa tacaaccacc atagtgttcc gaatgtttga taaagtgctg gccccagagc   2340

ttattccctc catcttagag aagtttataa gagtttacat gagagaacat gacttgcaag   2400

aggaggaact tctcttgctg tacatagagg atttactgaa tagatgcagc tcaaagtcca   2460

catcactctt tgaaacagca tgggaagcaa aggccatggc agtaatagcg tgtttatctg   2520

acacggacct catatttgat gccgtgctca agatcatgta tgcggcagtg gttccttgga   2580

gtgcagctgt ggagcaactg gtgaaacagc acctggaaat ggaccatccc aaagtcaagt   2640

tattacagga aagttacaaa ctaatggaga tgaaaaaact tttacgaggc tatggaataa   2700

gagaggtaaa tctcttaaac aaggaaataa tgagagtggt tagatacatt ctcaaacaag   2760

atgtcccatc ttctttagaa gatgctttaa aggtagccca agcgtttatg ttatctgatg   2820

atgagatcta cagtctaaga attattgacc tgattgatag agaacagggt gaagactgtc   2880

tccttctgtt gaagtctttg cctcctgctg aagctgagaa aactgcagaa agagtcatca   2940

tatgggcacg actggcatta caagaagagc cagatcattc taaagagggc aaggcctgga   3000

gaatgtctgt agcgaagaca tccgtggaca ttcttaagat actatgtgac attcagaaag   3060

acaatctgca gaagaaggac gaatgtgaag aaatgttgaa actatttaaa gaggttgcta   3120

gcttacagga gaactttgag gtctttcttt catttgaaga ttatagcaat agttccctgg   3180

tagcagatct ccgtgagcag cacattaaag ctcacgaagt tgcacaggcg aaacacaaac   3240

ctgggagcac cccagagccc atagctgctg aggtgaggag cccaagcatg gaatcaaagc   3300

tgcacagaca ggcactggcc ctgcagatgt ccaaacaaga gctggaggca gagctgacct   3360

tgagagcctt aaaagatggg aacatcaaaa cagcactgaa aaaatgcagc gacttgttta   3420

agtatcactg caatgctgac actgggaaat tgctatttct gacatgtcag aagctttgtc   3480

agatgttggc tgataatgtc ccagtgacag tgcctgtggg actgaatctt ccttccatga   3540

tacatgatct agcaagccaa gctgccacca tttgcagtcc agatttttta ctagatgctt   3600

tagaactatg taaacatact ttaatggctg tagagctttc cagacaatgc caaatggatg   3660

actgtggaat cctcatgaaa gcttcttttg ggacacataa agatccatat gaagagtggt   3720

cttacagtga cttcttcagt gaagatggaa ttgttcttga gtcacagatg gtgcttccag   3780

tgatttatga actgatttca tctcttgtgc ctctagctga aagcaagaga tatcccttgg   3840

agtctaccag tttgccatac tgctccctta atgaaggaga tggccttgtt ttacctgtta   3900

taaattccat ctctgccctg cttcagaatc ttcaggaatc tagccagtgg gagctagccc   3960

taagatttgt ggttggttca tttggtacct gtcttcagca ctctgtgtca aacttcatga   4020

atgccacttt gagtgaaaag ttatttggag agactacatt agttaaatca aggcatgttg   4080

ttatggaatt gaaagaaaaa gctgttatat ttatcaggga aaatgctaca acactactgc   4140

acaaagtatt taattgtcgc ttggtagatc ttgacctggc gttgggttac tgcactctct   4200

tacctcaaaa agatgtgttt gaaaatctct ggaagctcat agataaagca tggcagaatt   4260

acgacaaaat cttggcaata tctctggtgg gctctgagct ggcaagtctc tatcaggaaa   4320

tagaaatggg gcttaagttc cgtgaactca gtactgatgc ccagtggggc attcgtcttg   4380

gtaaacttgg tatttctttt caaccagttt tcaggcaaca ttttctcacc aagaaagacc   4440

tcattaaagc tcttgtggag aatatagata tggacacaag cctcattttg gaatattgca   4500

gcacatttca gttggactgc gatgcagttc ttcagctctt cattgaaacg ctgctccaca   4560

acacaaatgc cggccaaggc cagggagatg caagcatgga ctctgcaaag cggcggcatc   4620

ccaaactcct ggccaaagcc cttgagatgg ttcctttact gacgagcaca aaagatttgg   4680

tcatcagtct tagtggaata ctacataagt tggatcctta tgactatgaa atgattgaag   4740

ttgtcttgaa agttatagaa cgagctgatg aaaagataac caatattaat attaatcagg   4800

cattgagtat tctgaaacat ttgaagtcat acagaagaat ttctcctccc gtggatctag   4860

aatatcagta tatgttggaa catgtcataa ctttgccatc agctgcccaa actagactgc   4920

cttttcacct gatattcttt ggcacagcac agaacttctg gaaaattctc tctacagaac   4980

tcagtgaaga atctttccca acattgctct taatttcgaa attaatgaag ttctctctgg   5040

acactctgta cgtgtctaca gcaaaacacg ttttcgaaaa aaaactgaag ccaaagctcc   5100

tgaagttaac acaagctaaa tcctcaacac tgattaacaa ggaaataact aagatcacgc   5160

agaccatcga atcctgctta ctctctatag tcaacccaga gtgggctgta gctattgcca   5220

tcagccttgc ccaggatatc cctgaaggtt ccttcaagat atctgctttg aaattctgcc   5280

tttatttagc tgagagatgg ctacagaata tcccatcgca ggacgaaaaa cgtgaaaaag   5340

ccgaggcttt gttgaagaag cttcatatcc agtaccggcg atcgggcaca gaagctgtgc   5400

tcatagccca caagctgaac actgaggaat atttaagagt gatcggaaag ccagcacatc   5460

ttattgtcag tctctacgaa catcctagca tcaatcaaag aattcagaat tcatctggca   5520

cagattatcc tgatattcat gcagcagcta aagaaatagc cgaagtcaat gaaattaatt   5580

tggaaaaagt ctgggacatg ttgttggaaa aatggctatg cccttcaaca aaacctggtg   5640

aaaaaccatc agaattattt gaacttcaag aagatgaagc cctacgaaga gtgcagtatc   5700

tcctcctgtc tcgtccaatt gattatagtt caagaatgct gtttgtattt gcaacatcaa   5760

ctacaaccac attaggtatg catcagttaa cttttgccca tagaactcga gctcttcagt   5820

gtctcttcta tttggctgac aaggaaacta tagaatctct ctttaaaaaa cccattgaag   5880

aagtgaaatc ttatttgaga tgtataactt ttctggcatc atttgagact ttgaatatcc   5940

ccatcacata tgaattattt tgcagcagtc ctaaagaagg aatgattaag ggtctgtgga   6000

aaaaccacag ccacgagtcc atggcagtaa gattggtgac tgagctgtgt ttagaataca   6060

aaatctatga cctgcagctt tggaatggac tcttgcaaaa gcttctgggc ttcaatatga   6120

ttccttatct aaggaaagtt ttaaaagcca tctccagtat ccattcttta tggcaggttc   6180

cctacttcag caaagcgtgg cagcgtgtga tacagatacc actgctttca gcctcttgtc   6240

ctttaagtcc tgatcagctg tcagattgtt ctgagagtct catcgctgtc ctcgaatgtc   6300

cagtctcagg tgatcttgac ctgatcggag tcgccaggca gtatatccag ttagaacttc   6360

cggcttttgc attagcttgt ctgatgctca tgccccactc agagaaaaga caccagcaaa   6420

ttaagaattt tctgggttcc tgtgaccctc aggttatttt aaagcaattg gaagagcata   6480

tgaacacggg ccagctagca ggattttcac atcaaattag aagtctgatt ttgaataata   6540

tcatcaataa gaaggagttt gggattttgg caaagaccaa atactttcaa atgttgaaga   6600

tgcatgcgat gaataccaac aatatcactg agctagtgaa ctatttggca aatgacttaa   6660

gtttagatga agcttcagtc ttgataactg aatattcaaa gcactgcggg aaacctgtgc   6720

ctccagacac tgctccctgt gaaattctga agatgtttct tagtggatta tcgtaaatca   6780

ctgaaccttt ttttcaagaa ggacaagaat tttggagtct gctattaatg gaccatattt   6840

attacagttt ttaaattgta caatctctgt attatagcta tttgtctaac attaccccac   6900

atgtaataaa taaaacaata tgagcataat tgccccataa agaactc                 6947


<210>  8209
<211>  2209
<212>  PRT
<213>  Homo sapiens

<400>  8209

Met Trp Asn Asp Ile Glu Leu Leu Thr Asn Asp Asp Thr Gly Ser Gly 
1               5                   10                  15


Tyr Leu Ser Val Gly Ser Arg Lys Glu His Gly Thr Ala Leu Tyr Gln 
            20                  25                  30


Val Asp Leu Leu Val Lys Ile Ser Ser Glu Lys Ala Ser Leu Asn Pro 
        35                  40                  45


Lys Ile Gln Ala Cys Ser Leu Ser Asp Gly Phe Ile Ile Val Ala Asp 
    50                  55                  60


Gln Ser Val Ile Leu Leu Asp Ser Ile Cys Arg Ser Leu Gln Leu His 
65                  70                  75                  80


Leu Val Phe Asp Thr Glu Val Asp Val Val Gly Leu Cys Gln Glu Gly 
                85                  90                  95


Lys Phe Leu Leu Val Gly Glu Arg Ser Gly Asn Leu His Leu Ile His 
            100                 105                 110


Val Thr Ser Lys Gln Thr Leu Leu Thr Asn Ala Phe Val Gln Lys Ala 
        115                 120                 125


Asn Asp Glu Asn Arg Arg Thr Tyr Gln Asn Leu Val Ile Glu Lys Asp 
    130                 135                 140


Gly Ser Asn Glu Gly Thr Tyr Tyr Met Leu Leu Leu Thr Tyr Ser Gly 
145                 150                 155                 160


Phe Phe Cys Ile Thr Asn Leu Gln Leu Leu Lys Ile Gln Gln Ala Ile 
                165                 170                 175


Glu Asn Val Asp Phe Ser Thr Ala Lys Lys Leu Gln Gly Gln Ile Lys 
            180                 185                 190


Ser Ser Phe Ile Ser Thr Glu Asn Tyr His Thr Leu Gly Cys Leu Ser 
        195                 200                 205


Leu Val Ala Gly Asp Leu Ala Ser Glu Val Pro Val Ile Ile Gly Gly 
    210                 215                 220


Thr Gly Asn Cys Ala Phe Ser Lys Trp Glu Pro Asp Ser Ser Lys Lys 
225                 230                 235                 240


Gly Met Thr Val Lys Asn Leu Ile Asp Ala Glu Ile Ile Lys Gly Ala 
                245                 250                 255


Lys Lys Phe Gln Leu Ile Asp Asn Leu Leu Phe Val Leu Asp Thr Asp 
            260                 265                 270


Asn Val Leu Ser Leu Trp Asp Ile Tyr Thr Leu Thr Pro Val Trp Asn 
        275                 280                 285


Trp Pro Ser Leu His Val Glu Glu Phe Leu Leu Thr Thr Glu Ala Asp 
    290                 295                 300


Ser Pro Ser Ser Val Thr Trp Gln Gly Ile Thr Asn Leu Lys Leu Ile 
305                 310                 315                 320


Ala Leu Thr Ala Ser Ala Asn Lys Lys Met Lys Asn Leu Met Val Tyr 
                325                 330                 335


Ser Leu Pro Thr Met Glu Ile Leu Tyr Ser Leu Glu Val Ser Ser Val 
            340                 345                 350


Ser Ser Leu Val Gln Thr Gly Ile Ser Thr Asp Thr Ile Tyr Leu Leu 
        355                 360                 365


Glu Gly Val Cys Lys Asn Asp Pro Lys Leu Ser Glu Asp Ser Val Ser 
    370                 375                 380


Val Leu Val Leu Arg Cys Leu Thr Glu Ala Leu Pro Glu Asn Arg Leu 
385                 390                 395                 400


Ser Arg Leu Leu His Lys His Arg Phe Ala Glu Ala Glu Ser Phe Ala 
                405                 410                 415


Ile Gln Phe Gly Leu Asp Val Glu Leu Val Tyr Lys Val Lys Ser Asn 
            420                 425                 430


His Ile Leu Glu Lys Leu Ala Leu Ser Ser Val Asp Ala Ser Glu Gln 
        435                 440                 445


Thr Glu Trp Gln Gln Leu Val Asp Asp Ala Lys Glu Asn Leu His Lys 
    450                 455                 460


Ile Gln Asp Asp Glu Phe Val Val Asn Tyr Cys Leu Lys Ala Gln Trp 
465                 470                 475                 480


Ile Thr Tyr Glu Thr Thr Gln Glu Met Leu Asn Tyr Ala Lys Thr Arg 
                485                 490                 495


Leu Leu Lys Lys Glu Asp Lys Thr Ala Leu Ile Tyr Ser Asp Gly Leu 
            500                 505                 510


Lys Glu Val Leu Arg Ala His Ala Lys Leu Thr Thr Phe Tyr Gly Ala 
        515                 520                 525


Phe Gly Pro Glu Lys Phe Ser Gly Ser Ser Trp Ile Glu Phe Leu Asn 
    530                 535                 540


Asn Glu Asp Asp Leu Lys Asp Ile Phe Leu Gln Leu Lys Glu Gly Asn 
545                 550                 555                 560


Leu Val Cys Ala Gln Tyr Leu Trp Leu Arg His Arg Ala Asn Phe Glu 
                565                 570                 575


Ser Arg Phe Asp Val Lys Met Leu Glu Ser Leu Leu Asn Ser Met Ser 
            580                 585                 590


Ala Ser Val Ser Leu Gln Lys Leu Cys Pro Trp Phe Lys Asn Asp Val 
        595                 600                 605


Ile Pro Phe Val Arg Arg Thr Val Pro Glu Gly Gln Ile Ile Leu Ala 
    610                 615                 620


Lys Trp Leu Glu Gln Ala Ala Arg Asn Leu Glu Leu Thr Asp Lys Ala 
625                 630                 635                 640


Asn Trp Pro Glu Asn Gly Leu Gln Leu Ala Glu Ile Phe Phe Thr Ala 
                645                 650                 655


Glu Lys Thr Asp Glu Leu Gly Leu Ala Ser Ser Trp His Trp Ile Ser 
            660                 665                 670


Leu Lys Asp Tyr Gln Asn Thr Glu Glu Val Cys Gln Leu Arg Thr Leu 
        675                 680                 685


Val Asn Asn Leu Arg Glu Leu Ile Thr Leu His Arg Lys Tyr Asn Cys 
    690                 695                 700


Lys Leu Ala Leu Ser Asp Phe Glu Lys Glu Asn Thr Thr Thr Ile Val 
705                 710                 715                 720


Phe Arg Met Phe Asp Lys Val Leu Ala Pro Glu Leu Ile Pro Ser Ile 
                725                 730                 735


Leu Glu Lys Phe Ile Arg Val Tyr Met Arg Glu His Asp Leu Gln Glu 
            740                 745                 750


Glu Glu Leu Leu Leu Leu Tyr Ile Glu Asp Leu Leu Asn Arg Cys Ser 
        755                 760                 765


Ser Lys Ser Thr Ser Leu Phe Glu Thr Ala Trp Glu Ala Lys Ala Met 
    770                 775                 780


Ala Val Ile Ala Cys Leu Ser Asp Thr Asp Leu Ile Phe Asp Ala Val 
785                 790                 795                 800


Leu Lys Ile Met Tyr Ala Ala Val Val Pro Trp Ser Ala Ala Val Glu 
                805                 810                 815


Gln Leu Val Lys Gln His Leu Glu Met Asp His Pro Lys Val Lys Leu 
            820                 825                 830


Leu Gln Glu Ser Tyr Lys Leu Met Glu Met Lys Lys Leu Leu Arg Gly 
        835                 840                 845


Tyr Gly Ile Arg Glu Val Asn Leu Leu Asn Lys Glu Ile Met Arg Val 
    850                 855                 860


Val Arg Tyr Ile Leu Lys Gln Asp Val Pro Ser Ser Leu Glu Asp Ala 
865                 870                 875                 880


Leu Lys Val Ala Gln Ala Phe Met Leu Ser Asp Asp Glu Ile Tyr Ser 
                885                 890                 895


Leu Arg Ile Ile Asp Leu Ile Asp Arg Glu Gln Gly Glu Asp Cys Leu 
            900                 905                 910


Leu Leu Leu Lys Ser Leu Pro Pro Ala Glu Ala Glu Lys Thr Ala Glu 
        915                 920                 925


Arg Val Ile Ile Trp Ala Arg Leu Ala Leu Gln Glu Glu Pro Asp His 
    930                 935                 940


Ser Lys Glu Gly Lys Ala Trp Arg Met Ser Val Ala Lys Thr Ser Val 
945                 950                 955                 960


Asp Ile Leu Lys Ile Leu Cys Asp Ile Gln Lys Asp Asn Leu Gln Lys 
                965                 970                 975


Lys Asp Glu Cys Glu Glu Met Leu Lys Leu Phe Lys Glu Val Ala Ser 
            980                 985                 990


Leu Gln Glu Asn Phe Glu Val Phe Leu Ser Phe Glu Asp Tyr Ser Asn 
        995                 1000                1005


Ser Ser Leu Val Ala Asp Leu Arg Glu Gln His Ile Lys Ala His Glu 
    1010                1015                1020


Val Ala Gln Ala Lys His Lys Pro Gly Ser Thr Pro Glu Pro Ile Ala 
1025                1030                1035                1040


Ala Glu Val Arg Ser Pro Ser Met Glu Ser Lys Leu His Arg Gln Ala 
                1045                1050                1055


Leu Ala Leu Gln Met Ser Lys Gln Glu Leu Glu Ala Glu Leu Thr Leu 
            1060                1065                1070


Arg Ala Leu Lys Asp Gly Asn Ile Lys Thr Ala Leu Lys Lys Cys Ser 
        1075                1080                1085


Asp Leu Phe Lys Tyr His Cys Asn Ala Asp Thr Gly Lys Leu Leu Phe 
    1090                1095                1100


Leu Thr Cys Gln Lys Leu Cys Gln Met Leu Ala Asp Asn Val Pro Val 
1105                1110                1115                1120


Thr Val Pro Val Gly Leu Asn Leu Pro Ser Met Ile His Asp Leu Ala 
                1125                1130                1135


Ser Gln Ala Ala Thr Ile Cys Ser Pro Asp Phe Leu Leu Asp Ala Leu 
            1140                1145                1150


Glu Leu Cys Lys His Thr Leu Met Ala Val Glu Leu Ser Arg Gln Cys 
        1155                1160                1165


Gln Met Asp Asp Cys Gly Ile Leu Met Lys Ala Ser Phe Gly Thr His 
    1170                1175                1180


Lys Asp Pro Tyr Glu Glu Trp Ser Tyr Ser Asp Phe Phe Ser Glu Asp 
1185                1190                1195                1200


Gly Ile Val Leu Glu Ser Gln Met Val Leu Pro Val Ile Tyr Glu Leu 
                1205                1210                1215


Ile Ser Ser Leu Val Pro Leu Ala Glu Ser Lys Arg Tyr Pro Leu Glu 
            1220                1225                1230


Ser Thr Ser Leu Pro Tyr Cys Ser Leu Asn Glu Gly Asp Gly Leu Val 
        1235                1240                1245


Leu Pro Val Ile Asn Ser Ile Ser Ala Leu Leu Gln Asn Leu Gln Glu 
    1250                1255                1260


Ser Ser Gln Trp Glu Leu Ala Leu Arg Phe Val Val Gly Ser Phe Gly 
1265                1270                1275                1280


Thr Cys Leu Gln His Ser Val Ser Asn Phe Met Asn Ala Thr Leu Ser 
                1285                1290                1295


Glu Lys Leu Phe Gly Glu Thr Thr Leu Val Lys Ser Arg His Val Val 
            1300                1305                1310


Met Glu Leu Lys Glu Lys Ala Val Ile Phe Ile Arg Glu Asn Ala Thr 
        1315                1320                1325


Thr Leu Leu His Lys Val Phe Asn Cys Arg Leu Val Asp Leu Asp Leu 
    1330                1335                1340


Ala Leu Gly Tyr Cys Thr Leu Leu Pro Gln Lys Asp Val Phe Glu Asn 
1345                1350                1355                1360


Leu Trp Lys Leu Ile Asp Lys Ala Trp Gln Asn Tyr Asp Lys Ile Leu 
                1365                1370                1375


Ala Ile Ser Leu Val Gly Ser Glu Leu Ala Ser Leu Tyr Gln Glu Ile 
            1380                1385                1390


Glu Met Gly Leu Lys Phe Arg Glu Leu Ser Thr Asp Ala Gln Trp Gly 
        1395                1400                1405


Ile Arg Leu Gly Lys Leu Gly Ile Ser Phe Gln Pro Val Phe Arg Gln 
    1410                1415                1420


His Phe Leu Thr Lys Lys Asp Leu Ile Lys Ala Leu Val Glu Asn Ile 
1425                1430                1435                1440


Asp Met Asp Thr Ser Leu Ile Leu Glu Tyr Cys Ser Thr Phe Gln Leu 
                1445                1450                1455


Asp Cys Asp Ala Val Leu Gln Leu Phe Ile Glu Thr Leu Leu His Asn 
            1460                1465                1470


Thr Asn Ala Gly Gln Gly Gln Gly Asp Ala Ser Met Asp Ser Ala Lys 
        1475                1480                1485


Arg Arg His Pro Lys Leu Leu Ala Lys Ala Leu Glu Met Val Pro Leu 
    1490                1495                1500


Leu Thr Ser Thr Lys Asp Leu Val Ile Ser Leu Ser Gly Ile Leu His 
1505                1510                1515                1520


Lys Leu Asp Pro Tyr Asp Tyr Glu Met Ile Glu Val Val Leu Lys Val 
                1525                1530                1535


Ile Glu Arg Ala Asp Glu Lys Ile Thr Asn Ile Asn Ile Asn Gln Ala 
            1540                1545                1550


Leu Ser Ile Leu Lys His Leu Lys Ser Tyr Arg Arg Ile Ser Pro Pro 
        1555                1560                1565


Val Asp Leu Glu Tyr Gln Tyr Met Leu Glu His Val Ile Thr Leu Pro 
    1570                1575                1580


Ser Ala Ala Gln Thr Arg Leu Pro Phe His Leu Ile Phe Phe Gly Thr 
1585                1590                1595                1600


Ala Gln Asn Phe Trp Lys Ile Leu Ser Thr Glu Leu Ser Glu Glu Ser 
                1605                1610                1615


Phe Pro Thr Leu Leu Leu Ile Ser Lys Leu Met Lys Phe Ser Leu Asp 
            1620                1625                1630


Thr Leu Tyr Val Ser Thr Ala Lys His Val Phe Glu Lys Lys Leu Lys 
        1635                1640                1645


Pro Lys Leu Leu Lys Leu Thr Gln Ala Lys Ser Ser Thr Leu Ile Asn 
    1650                1655                1660


Lys Glu Ile Thr Lys Ile Thr Gln Thr Ile Glu Ser Cys Leu Leu Ser 
1665                1670                1675                1680


Ile Val Asn Pro Glu Trp Ala Val Ala Ile Ala Ile Ser Leu Ala Gln 
                1685                1690                1695


Asp Ile Pro Glu Gly Ser Phe Lys Ile Ser Ala Leu Lys Phe Cys Leu 
            1700                1705                1710


Tyr Leu Ala Glu Arg Trp Leu Gln Asn Ile Pro Ser Gln Asp Glu Lys 
        1715                1720                1725


Arg Glu Lys Ala Glu Ala Leu Leu Lys Lys Leu His Ile Gln Tyr Arg 
    1730                1735                1740


Arg Ser Gly Thr Glu Ala Val Leu Ile Ala His Lys Leu Asn Thr Glu 
1745                1750                1755                1760


Glu Tyr Leu Arg Val Ile Gly Lys Pro Ala His Leu Ile Val Ser Leu 
                1765                1770                1775


Tyr Glu His Pro Ser Ile Asn Gln Arg Ile Gln Asn Ser Ser Gly Thr 
            1780                1785                1790


Asp Tyr Pro Asp Ile His Ala Ala Ala Lys Glu Ile Ala Glu Val Asn 
        1795                1800                1805


Glu Ile Asn Leu Glu Lys Val Trp Asp Met Leu Leu Glu Lys Trp Leu 
    1810                1815                1820


Cys Pro Ser Thr Lys Pro Gly Glu Lys Pro Ser Glu Leu Phe Glu Leu 
1825                1830                1835                1840


Gln Glu Asp Glu Ala Leu Arg Arg Val Gln Tyr Leu Leu Leu Ser Arg 
                1845                1850                1855


Pro Ile Asp Tyr Ser Ser Arg Met Leu Phe Val Phe Ala Thr Ser Thr 
            1860                1865                1870


Thr Thr Thr Leu Gly Met His Gln Leu Thr Phe Ala His Arg Thr Arg 
        1875                1880                1885


Ala Leu Gln Cys Leu Phe Tyr Leu Ala Asp Lys Glu Thr Ile Glu Ser 
    1890                1895                1900


Leu Phe Lys Lys Pro Ile Glu Glu Val Lys Ser Tyr Leu Arg Cys Ile 
1905                1910                1915                1920


Thr Phe Leu Ala Ser Phe Glu Thr Leu Asn Ile Pro Ile Thr Tyr Glu 
                1925                1930                1935


Leu Phe Cys Ser Ser Pro Lys Glu Gly Met Ile Lys Gly Leu Trp Lys 
            1940                1945                1950


Asn His Ser His Glu Ser Met Ala Val Arg Leu Val Thr Glu Leu Cys 
        1955                1960                1965


Leu Glu Tyr Lys Ile Tyr Asp Leu Gln Leu Trp Asn Gly Leu Leu Gln 
    1970                1975                1980


Lys Leu Leu Gly Phe Asn Met Ile Pro Tyr Leu Arg Lys Val Leu Lys 
1985                1990                1995                2000


Ala Ile Ser Ser Ile His Ser Leu Trp Gln Val Pro Tyr Phe Ser Lys 
                2005                2010                2015


Ala Trp Gln Arg Val Ile Gln Ile Pro Leu Leu Ser Ala Ser Cys Pro 
            2020                2025                2030


Leu Ser Pro Asp Gln Leu Ser Asp Cys Ser Glu Ser Leu Ile Ala Val 
        2035                2040                2045


Leu Glu Cys Pro Val Ser Gly Asp Leu Asp Leu Ile Gly Val Ala Arg 
    2050                2055                2060


Gln Tyr Ile Gln Leu Glu Leu Pro Ala Phe Ala Leu Ala Cys Leu Met 
2065                2070                2075                2080


Leu Met Pro His Ser Glu Lys Arg His Gln Gln Ile Lys Asn Phe Leu 
                2085                2090                2095


Gly Ser Cys Asp Pro Gln Val Ile Leu Lys Gln Leu Glu Glu His Met 
            2100                2105                2110


Asn Thr Gly Gln Leu Ala Gly Phe Ser His Gln Ile Arg Ser Leu Ile 
        2115                2120                2125


Leu Asn Asn Ile Ile Asn Lys Lys Glu Phe Gly Ile Leu Ala Lys Thr 
    2130                2135                2140


Lys Tyr Phe Gln Met Leu Lys Met His Ala Met Asn Thr Asn Asn Ile 
2145                2150                2155                2160


Thr Glu Leu Val Asn Tyr Leu Ala Asn Asp Leu Ser Leu Asp Glu Ala 
                2165                2170                2175


Ser Val Leu Ile Thr Glu Tyr Ser Lys His Cys Gly Lys Pro Val Pro 
            2180                2185                2190


Pro Asp Thr Ala Pro Cys Glu Ile Leu Lys Met Phe Leu Ser Gly Leu 
        2195                2200                2205


Ser 



<210>  8210
<211>  491
<212>  DNA
<213>  Homo sapiens

<400>  8210
gcggttgtgt gagtcaggaa gaggggccag atatctgagt gttcctcttt agtttcttca     60

attgcaggaa agacagtggt tcctgactca ggaagacagt ctcagaaaca tgtggaatga    120

tattgagctg ctaacaaatg atgataccgg aagtgggtac ctgagtgtcg gttcaagaaa    180

agaaacatct ctgcactttc tccaagcttc taatttttac cccagtgcca agaaatagca    240

gaaccaaact ggaagccacc tggctagaag tctgggagga gtggtccgca actgtaaacc    300

cccagcactg cagccggtgg cctagaaagg cgtgtggagc aaaaagccag cacacagaag    360

tgttaattac acctgttatt ctgactttgt agtcctttgc catacttgcg aataacttaa    420

gtgaatttga tgttactgga attagtttgc ctttattttg ccagttgaaa aaaaagattt    480

ctaaaaaact c                                                         491


<210>  8211
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  8211

Met Trp Asn Asp Ile Glu Leu Leu Thr Asn Asp Asp Thr Gly Ser Gly 
1               5                   10                  15


Tyr Leu Ser Val Gly Ser Arg Lys Glu Thr Ser Leu His Phe Leu Gln 
            20                  25                  30


Ala Ser Asn Phe Tyr Pro Ser Ala Lys Lys 
        35                  40


<210>  8212
<211>  538
<212>  DNA
<213>  Homo sapiens

<400>  8212
ggatgtggcg agctagtgat taaaaaaaac tttttttttt atttgaccga gattgtgcca     60

cttcactgca gcctgggtga cagtgagact ccagctcaaa aaaataaagt aaaataatat    120

aaacatgcct gtaatcccat ctattcagga tgctgaggtg gcaggattgc ttgagcccag    180

gaattcaagt ccagcctgag cacatagtga gatcccatct caaaaaaaca aataaaacaa    240

acaagagtga aaaatagtta tttctacgtg tagtgattat ctgaggaggg tcctatagga    300

agctacatgg ctctgaggaa gatgtcggga gttctagggt ctgagataag aaggaaatgt    360

actttgcatt gtgtgatctt tggaactggg ttttttttag ttttttgttt ttacctttat    420

gaagaagaaa actaattaaa atgcatttaa agataatcca cttaaaaggt ataaccttaa    480

ttttttttaa aactgacttt tttcccttct ttgtctattc agtggcagtt cttggatt      538


<210>  8213
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  8213

Met Ala Leu Arg Lys Met Ser Gly Val Leu Gly Ser Glu Ile Arg Arg 
1               5                   10                  15


Lys Cys Thr Leu His Cys Val Ile Phe Gly Thr Gly Phe Phe Leu Val 
            20                  25                  30


Phe Cys Phe Tyr Leu Tyr Glu Glu Glu Asn 
        35                  40


<210>  8214
<211>  1262
<212>  DNA
<213>  Homo sapiens

<400>  8214
attttttgta ttttagtaga gacagggttt cactgtattg gccaggatgg tctcccatct     60

cttgacctcg tgatccgccc acgtcggcct cccaaagtgc tgggattaca gacatgagct    120

accgcgccca gccttgagct ttatttttga cattgtaaaa gaacagacaa gcaggcaggg    180

cgcaatcttg tctttgacag gatctcattc tgtcacccag gctggagtgc agtggcatta    240

tcatggctca ctgcagcctt gacctctagg gcctaagtga tcctcccagc ttagcctcct    300

gagtagctgg gactacaggc atgcaccacc atgcccagct aattgttttg tatttttttg    360

tagagacaag gtttccatgt tggccaagct ggtctcaaac tcctgacctc aagtgatcca    420

cccgcctcag cctcccacag tgctgggatt ataggcatga gccaaaaccc tgttttcttt    480

accaaaaata taagacattt tatttgccaa cagttgactt atcagaaagg taatcagtac    540

agaaatgcta tatgttttga agcttaattc ttctgcagta atggaactgg tgttctgttg    600

acattaacaa tcaaactttt cagatgaaga ggcaatggtt aggatgacta agaggagttt    660

cggacccatg tacacctcaa atctcagaat gatggctggg ttgggtagtg tgaggttgga    720

ggagctatag acaaatgttt ctttttgaaa aaggatacta agaaggcaag tcatgatgtt    780

gcccttactc tgatacattt cagtgtagag ggtttttttg ctttgttttt ttctttttat    840

ttctagattt cttttcaacc agttttcagg caacattttc tcaccaagaa agacctcatt    900

aaagctcttg tggagaatat agatatggac acaagcctca ttttggaata ttgcagcaca    960

tttcagttgg actgcgatgc agttcttcag ctcttcattg aaacgctgct ccacaacaca   1020

aatgccggcc aaggccaggg agatgcaagc atggactctg caaagcggcg gcatcccaaa   1080

ctcctggcca aagcccttga gatggttcct ttactgacga gcacaaaaga tttggtcatc   1140

agtcttagtg gaatactaca taaggtgatt taaataacct ctcctgctgt cgaagagtat   1200

gaagtcacta cagaactaat tgtgaagaat taaggaaaca tttgccatgt aggaagtgaa   1260

aa                                                                  1262


<210>  8215
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  8215

Met Asp Thr Ser Leu Ile Leu Glu Tyr Cys Ser Thr Phe Gln Leu Asp 
1               5                   10                  15


Cys Asp Ala Val Leu Gln Leu Phe Ile Glu Thr Leu Leu His Asn Thr 
            20                  25                  30


Asn Ala Gly Gln Gly Gln Gly Asp Ala Ser Met Asp Ser Ala Lys Arg 
        35                  40                  45


Arg His Pro Lys Leu Leu Ala Lys Ala Leu Glu Met Val Pro Leu Leu 
    50                  55                  60


Thr Ser Thr Lys Asp Leu Val Ile Ser Leu Ser Gly Ile Leu His Lys 
65                  70                  75                  80


Val Ile 



<210>  8216
<211>  2415
<212>  DNA
<213>  Homo sapiens

<400>  8216
tatagtttag atgaataatg ttaaagagaa tactagaaaa ggttttgatc ctctttctga     60

aaacaagatg gtctcaggaa tggaaacttt tgatggtata ctattagatg attttatgac    120

agtttaggat tgggttactc ttactggaca aaagtttttt attttaatat aggcattgag    180

tattctgaaa catttgaagt catacagaag aatttctcct cccgtggatc tagaatatca    240

gtatatgttg gaacatgtca taactttgcc atcagctgcc caaactagac tgccttttca    300

cctgatattc tttggcacag cacagaactt ctggaaaatt ctctctacag aactcagtga    360

agaatctttc ccaacattgc tcttaatttc gaaattaatg aagttctctc tggacactct    420

gtacgtgtct acagcaaaac acgttttcga aaaaaaactg aagccaaagc tcctgaagtt    480

aacacaagct aaatcctcaa cactgattaa caaggaaata actaagatca cgcagaccat    540

cgaatcctgc ttactctcta tagtcaaccc agagtgggct gtagctattg ccatcagcct    600

tgcccaggat atccctgaag gttccttcaa gatatctgct ttgaaattct gcctttattt    660

agctgagaga tggctacaga atatcccatc gcaggacgaa aaacgtgaaa aagccgaggc    720

tttgttgaag aagcttcata tccagtaccg gcgatcgggc acagaagctg tgctcatagc    780

ccacaagctg aacactgagg aatatttaag agtgatcgga aagccagcac atcttattgt    840

cagtctctac gaacatccta gcatcaatca aagaattcag aattcatctg gcacagatta    900

tcctgatatt catgcagcag ctaaagaaat agccgaagtc aatgaaatta atttggaaaa    960

agtctgggac atgttgttgg aaaaatggct atgcccttca acaaaacctg gtgaaaaacc   1020

atcagaatta tttgaacttc aagaagatga agccctacga agagtgcagt atctcctcct   1080

gtctcgtcca attgattata gttcaagaat gctgtttgta tttgcaacat caactacaac   1140

cacattaggt atgcatcagt taacttttgc ccatagaact cgagctcttc agtgtctctt   1200

ctatttggct gacaaggaaa ctatagaatc tctctttaaa aaacccattg aagaagtgaa   1260

atcttatttg agatgtataa cttttctggc atcatttgag actttgaata tccccatcac   1320

atatgaatta ttttgcagca gtcctaaaga aggaatgatt aagggtctgt ggaaaaacca   1380

cagccacgag tccatggcag taagattggt gactgagctg tgtttagaat acaaaatcta   1440

tgacctgcag ctttggaatg gactcttgca aaagcttctg ggcttcaata tgattcctta   1500

tctaaggaaa gttttaaaag ccatctccag tatccattct ttatggcaga gatggaggtc   1560

ttgctatgtt gcctaggctg gtcttagaac tcctgagctg aaacaatcct cctgccttgg   1620

cctcccaaag tactgggatt acaggttccc tacttcagca aagcgtggca gcgtgtgata   1680

cagataccac tgctttcagc ctcttgtcct ttaagtcctg atcagctgtc agattgttct   1740

gagagtctca tcgctgtcct cgaatgtcca gtctcaggtg atcttgacct gatcggagtc   1800

gccaggcagt atatccagtt agaacttccg gcttttgcat tagcttgtct gatgctcatg   1860

ccccactcag agaaaagaca ccagcaaatt aagaattttc tgggttcctg tgaccctcag   1920

gttattttaa agcaattgga agagcatatg aacacgggcc agctagcagg attttcacat   1980

caaattagaa gtctgatttt gaataatatc atcaataaga aggagtttgg gattttggca   2040

aagaccaaat actttcaaat gttgaagatg catgcgatga ataccaacaa tatcactgag   2100

ctagtgaact atttggcaaa tgacttaagt ttagatgaag cttcagtctt gataactgaa   2160

tattcaaagc actgcgggaa acctgtgcct ccagacactg ctccctgtga aattctgaag   2220

atgtttctta gtggattatc gtaaatcact gaaccttttt ttcaagaagg acaagaattt   2280

tggagtctgc tattaatgga ccatatttat tacagttttt aaattgtaca atctctgtat   2340

tatagctatt tgtctaacat taccccacat gtaataaata aaacaatatg agcataattg   2400

ccccataaag aactc                                                    2415


<210>  8217
<211>  443
<212>  PRT
<213>  Homo sapiens

<400>  8217

Met Leu Glu His Val Ile Thr Leu Pro Ser Ala Ala Gln Thr Arg Leu 
1               5                   10                  15


Pro Phe His Leu Ile Phe Phe Gly Thr Ala Gln Asn Phe Trp Lys Ile 
            20                  25                  30


Leu Ser Thr Glu Leu Ser Glu Glu Ser Phe Pro Thr Leu Leu Leu Ile 
        35                  40                  45


Ser Lys Leu Met Lys Phe Ser Leu Asp Thr Leu Tyr Val Ser Thr Ala 
    50                  55                  60


Lys His Val Phe Glu Lys Lys Leu Lys Pro Lys Leu Leu Lys Leu Thr 
65                  70                  75                  80


Gln Ala Lys Ser Ser Thr Leu Ile Asn Lys Glu Ile Thr Lys Ile Thr 
                85                  90                  95


Gln Thr Ile Glu Ser Cys Leu Leu Ser Ile Val Asn Pro Glu Trp Ala 
            100                 105                 110


Val Ala Ile Ala Ile Ser Leu Ala Gln Asp Ile Pro Glu Gly Ser Phe 
        115                 120                 125


Lys Ile Ser Ala Leu Lys Phe Cys Leu Tyr Leu Ala Glu Arg Trp Leu 
    130                 135                 140


Gln Asn Ile Pro Ser Gln Asp Glu Lys Arg Glu Lys Ala Glu Ala Leu 
145                 150                 155                 160


Leu Lys Lys Leu His Ile Gln Tyr Arg Arg Ser Gly Thr Glu Ala Val 
                165                 170                 175


Leu Ile Ala His Lys Leu Asn Thr Glu Glu Tyr Leu Arg Val Ile Gly 
            180                 185                 190


Lys Pro Ala His Leu Ile Val Ser Leu Tyr Glu His Pro Ser Ile Asn 
        195                 200                 205


Gln Arg Ile Gln Asn Ser Ser Gly Thr Asp Tyr Pro Asp Ile His Ala 
    210                 215                 220


Ala Ala Lys Glu Ile Ala Glu Val Asn Glu Ile Asn Leu Glu Lys Val 
225                 230                 235                 240


Trp Asp Met Leu Leu Glu Lys Trp Leu Cys Pro Ser Thr Lys Pro Gly 
                245                 250                 255


Glu Lys Pro Ser Glu Leu Phe Glu Leu Gln Glu Asp Glu Ala Leu Arg 
            260                 265                 270


Arg Val Gln Tyr Leu Leu Leu Ser Arg Pro Ile Asp Tyr Ser Ser Arg 
        275                 280                 285


Met Leu Phe Val Phe Ala Thr Ser Thr Thr Thr Thr Leu Gly Met His 
    290                 295                 300


Gln Leu Thr Phe Ala His Arg Thr Arg Ala Leu Gln Cys Leu Phe Tyr 
305                 310                 315                 320


Leu Ala Asp Lys Glu Thr Ile Glu Ser Leu Phe Lys Lys Pro Ile Glu 
                325                 330                 335


Glu Val Lys Ser Tyr Leu Arg Cys Ile Thr Phe Leu Ala Ser Phe Glu 
            340                 345                 350


Thr Leu Asn Ile Pro Ile Thr Tyr Glu Leu Phe Cys Ser Ser Pro Lys 
        355                 360                 365


Glu Gly Met Ile Lys Gly Leu Trp Lys Asn His Ser His Glu Ser Met 
    370                 375                 380


Ala Val Arg Leu Val Thr Glu Leu Cys Leu Glu Tyr Lys Ile Tyr Asp 
385                 390                 395                 400


Leu Gln Leu Trp Asn Gly Leu Leu Gln Lys Leu Leu Gly Phe Asn Met 
                405                 410                 415


Ile Pro Tyr Leu Arg Lys Val Leu Lys Ala Ile Ser Ser Ile His Ser 
            420                 425                 430


Leu Trp Gln Arg Trp Arg Ser Cys Tyr Val Ala 
        435                 440


<210>  8218
<211>  710
<212>  DNA
<213>  Homo sapiens

<400>  8218
ggtctcagga atggaaactt ttgatggtat actattagat gattttatga cagtttagga     60

ttgggttact cttactggac aaaagttttt tattttaata taggcattga gtattctgaa    120

acatttgaag tcatacagaa gaatttctcc tcccgtggat ctagaatatc agtatatgtt    180

ggaacatgtc ataactttgc catcagctgc ccaaactaga ctgccttttc acctgatatt    240

ctttggcaca gcacagaact tctggaaaat tctctctaca gaactcagtg aagaatcttt    300

cccaacattg ctcttaattt cgaaattaat gaaggtaatg gattaaaaca ttgtaagaca    360

tttctgtatc ctgcaattaa ttctgacccc gtatagaaga tttttctgct gctttcatgt    420

aaaaccttat atgtgaatat gtgcttcagc cataaccttc cttttctttg aagttctctc    480

tggacactct gtacgtgtct acagcaaaac acgttttcga aaaaaaactg aagccaaagc    540

tcctgaagtt aacacaagct aaatcctcaa cactgattaa caaggaaata actaagatca    600

cgcagaccat cgaatcctgc ttactctcta tagtcaaccc agagtgggct gtagctattg    660

ccatcagcct tgcccaggat atccctgaag gtatgagctc ttcttttaaa               710


<210>  8219
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  8219

Met Leu Glu His Val Ile Thr Leu Pro Ser Ala Ala Gln Thr Arg Leu 
1               5                   10                  15


Pro Phe His Leu Ile Phe Phe Gly Thr Ala Gln Asn Phe Trp Lys Ile 
            20                  25                  30


Leu Ser Thr Glu Leu Ser Glu Glu Ser Phe Pro Thr Leu Leu Leu Ile 
        35                  40                  45


Ser Lys Leu Met Lys Val Met Asp 
    50                  55


<210>  8220
<211>  772
<212>  DNA
<213>  Homo sapiens

<400>  8220
tcctgttgcc caggctggag tgcaatggtg cgatctcggc tcactgcaac ctctgcctcc     60

cgggttgaag agattctcct gccttatcct ccctagtagc tgggattaca ggtttgctga    120

aatgaaaatg cgaccttttg caagggacat gcaagatgaa accttctatt tccttggcag    180

cccagaggaa tcatgtgcac gataccttaa tttgctggtg tcttttctct gagtggggca    240

tgagcatcag acaagctaat gcaaaagccg gaagttctaa ctggatatac tgcctggcga    300

ctccgatcag gtcaagatca cctgagactg gacatcttcg agagagaaca ttaattagtt    360

aataatctgg cagattcact agattatatt ggcctttcta gctttccata gtcatctgcc    420

tgtccaagtt ttcaataatt ttaaacacta aagtgctggt gcatgacata tgcttaggaa    480

tgagtaacac aagtctttga cagcactcta cacagaataa aagaatttac ccatgggaac    540

acggactact gtttgctatc atgattatgt ctgaaagcct acagatgcct aaagataggc    600

ttctaaattc tcagaagact caaaaccttt tttttttttt tttttgagaa acagtctagc    660

tctgtcaccc aggctggagt acgatggcat gatcttagct cactgcaacc aacacctccc    720

gggttcaagt gattctccct cctcagcttc ctgagtagct gggattacag gc            772


<210>  8221
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  8221

Met Lys Pro Ser Ile Ser Leu Ala Ala Gln Arg Asn His Val His Asp 
1               5                   10                  15


Thr Leu Ile Cys Trp Cys Leu Phe Ser Glu Trp Gly Met Ser Ile Arg 
            20                  25                  30


Gln Ala Asn Ala Lys Ala Gly Ser Ser Asn Trp Ile Tyr Cys Leu Ala 
        35                  40                  45


Thr Pro Ile Arg Ser Arg Ser Pro Glu Thr Gly His Leu Arg Glu Arg 
    50                  55                  60


Thr Leu Ile Ser 
65


<210>  8222
<211>  2504
<212>  DNA
<213>  Homo sapiens

<400>  8222
aatgtttgga tttctccacc aggagggagg acaaacaagc tttcttcttg ccttctgggc     60

agctttgtgt gctctccagc acggagtccg aggaggaaca gcgaagctga aaatgaaaat    120

tactctggcg ctggacccaa tcgctcctct acggcatcaa tctcatcgga cccccccacc    180

ctaccgcctc tcagaaatga ccacttttgc aaaattgcat gcatttccaa gcttcatccg    240

gctccaggct tggcctctcc cagaggcagg cggcttgtga gacgggctcc agagaaagga    300

cctccctggg tctctcattt cctggctgaa gtttctcttc tcgctgctgt ggcagcatcc    360

aacccacaca cacaggaccc gcatcctggg tgatgaagtc agacacgcag cagctgggtg    420

agtgctaacg ctcagataag catctgtgcc attgtgggga ctccctgggc tgctctgcac    480

ccggacactt gctctgtccc cgccatgtac aacgggtcgt gctgccgcat cgagggggac    540

accatctccc aggtgatgcc gccgctgctc attgtggcct ttgtgctggg cgcactaggc    600

aatggggtcg ccctgtgtgg tttctgcttc cacatgaaga cctggaagcc cagcactgtt    660

taccttttca atttggccgt ggctgatttc ctccttatga tctgcctgcc ttttcggaca    720

gactattacc tcagacgtag acactgggct tttggggaca ttccctgccg agtggggctc    780

ttcacgttgg ccatgaacag ggccgggagc atcgtgttcc ttacggtggt ggctgcggac    840

aggtatttca aagtggtcca cccccaccac gcggtgaaca ctatctccac ccgggtggcg    900

gctggcatcg tctgcaccct gtgggccctg gtcatcctgg gaacagtgta tcttttgctg    960

gagaaccatc tctgcgtgca agagacggcc gtctcctgtg agagcttcat catggagtcg   1020

gccaatggct ggcatgacat catgttccag ctggagttct ttatgcccct cggcatcatc   1080

ttattttgct ccttcaagat tgtttggagc ctgaggcgga ggcagcagct ggccagacag   1140

gctcggatga agaaggcgac ccggttcatc atggtggtgg caattgtgtt catcacatgc   1200

tacctgccca gcgtgtctgc tagactctat ttcctctgga cggtgccctc gagtgcctgc   1260

gatccctctg tccatggggc cctgcacata accctcagct tcacctacat gaacagcatg   1320

ctggatcccc tggtgtatta tttttcaagc ccctcctttc ccaaattcta caacaagctc   1380

aaaatctgca gtctgaaacc caagcagcca ggacactcaa aaacacaaag gccggaagag   1440

atgccaattt cgaacctcgg tcgcaggagt tgcatcagtg tggcaaatag tttccaaagc   1500

cagtctgatg ggcaatggga tccccacatt gttgagtggc actgaacaag cagaccaaca   1560

acactgagga agatagagtg gtgacttaga attaactcgt gctaaggggt cgggggcttt   1620

gaaaatgcca cccccctttc ttattgcaag acggcttctc gcacatgaac tgcatccttc   1680

tcattctgtc ggaaatgaaa ttcacacaac tatacctttt ggggaggttc cagttgattg   1740

aaagagtgtt ccaaccacat cctccaggga aaatccctcg accaagagtc caatctgatt   1800

ttgcacttcc ctgacttctt gctaagccgt ctacaccagg agggtttgct gaaatgaaaa   1860

tgcgaccttt tgcaagggac atgcaagatg aaaccttcta tttccttggc agcccagagg   1920

aatcatgtgc acgatacctt aatttgctgg tgtcttttct ctgagtgggg catgagcatc   1980

agacaagcta atgcaaaagc cggaagttct aactggatat actgcctggc gactccgatc   2040

aggtcaagat cacctgagac tggacatctt cgagagagaa cattaattag ttaataatct   2100

ggcagattca ctagattata ttggcctttc tagctttcca tagtcatctg cctgtccaag   2160

ttttcaataa ttttaaacac taaagtgctg gtgcatgaca tatgcttagg aatgagtaac   2220

acaagtcttt gacagcactc tacacagaat aaaagaattt acccatggga acacggacta   2280

ctgtttgcta tcatgattat gtctgaaagc ctacagatgc ctaaagatag gcttctaaat   2340

tctcagaaga ctcaaaacct tttttttttt tttttttgag aaacagtcta gctctgtcac   2400

ccaggctgga gtacgatggc atgatcttag ctcactgcaa ccaacacctc ccgggttcaa   2460

gtgattctcc ctcctcagct tcctgagtag ctgggattac aggc                    2504


<210>  8223
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  8223

Met Asn Cys Ile Leu Leu Ile Leu Ser Glu Met Lys Phe Thr Gln Leu 
1               5                   10                  15


Tyr Leu Leu Gly Arg Phe Gln Leu Ile Glu Arg Val Phe Gln Pro His 
            20                  25                  30


Pro Pro Gly Lys Ile Pro Arg Pro Arg Val Gln Ser Asp Phe Ala Leu 
        35                  40                  45


Pro 



<210>  8224
<211>  542
<212>  DNA
<213>  Homo sapiens

<400>  8224
ttcgctcctg ttgcccaggc tggagtgcaa tggtgcgatc tcggctcact gcaacctctg     60

cctcccgggt tgaagagatt ctcctgcctt atcctcccta gtagctggga ttacaggttt    120

gctgaaatga aaatgcgacc ttttgcaagg gacatgcaag atgaaacctt ctatttcctt    180

ggcagcccag aggaatcatg tgcacgatac cttaatttgc tggtgtcttt tctctgagtg    240

gggcatgagc atcagacaag ctaatgcaaa agccggaagt tctaactgga tatactgcct    300

ggcgactccg atcaggtcaa gatcacctga gactggacat cttcgagaga gaacattaat    360

tagttaataa tctggcagat tcactagatt atattggcct ttctagcttt ccatagtcat    420

ctgcctgtcc aagttttcaa taattttaaa cactaaagtg ctggtgcatg acatatgctt    480

aggaatgagt aacacaagtc tttgacagca ctctacacag aataaaagaa tttacccatg    540

gg                                                                   542


<210>  8225
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  8225

Met Lys Pro Ser Ile Ser Leu Ala Ala Gln Arg Asn His Val His Asp 
1               5                   10                  15


Thr Leu Ile Cys Trp Cys Leu Phe Ser Glu Trp Gly Met Ser Ile Arg 
            20                  25                  30


Gln Ala Asn Ala Lys Ala Gly Ser Ser Asn Trp Ile Tyr Cys Leu Ala 
        35                  40                  45


Thr Pro Ile Arg Ser Arg Ser Pro Glu Thr Gly His Leu Arg Glu Arg 
    50                  55                  60


Thr Leu Ile Ser 
65


<210>  8226
<211>  2269
<212>  DNA
<213>  Homo sapiens

<400>  8226
aatgtttgga tttctccacc aggagggagg acaaacaagc tttcttcttg ccttctgggc     60

agctttgtgt gctctccagc acggagtccg aggaggaaca gcgaagctga aaatgaaaat    120

tactctggcg ctggacccaa tcgctcctct acggcatcaa tctcatcgga cccccccacc    180

ctaccgcctc tcagaaatga ccacttttgc aaaattgcat gcatttccaa gcttcatccg    240

gctccaggct tggcctctcc cagaggcagg cggcttgtga gacgggctcc agagaaagga    300

cctccctggg tctctcattt cctggctgaa gtttctcttc tcgctgctgt ggcagcatcc    360

aacccacaca cacaggaccc gcatcctggg tgatgaagtc agacacgcag cagctgggtg    420

agtgctaacg ctcagataag catctgtgcc attgtgggga ctccctgggc tgctctgcac    480

ccggacactt gctctgtccc cgccatgtac aacgggtcgt gctgccgcat cgagggggac    540

accatctccc aggtgatgcc gccgctgctc attgtggcct ttgtgctggg cgcactaggc    600

aatggggtcg ccctgtgtgg tttctgcttc cacatgaaga cctggaagcc cagcactgtt    660

taccttttca atttggccgt ggctgatttc ctccttatga tctgcctgcc ttttcggaca    720

gactattacc tcagacgtag acactgggct tttggggaca ttccctgccg agtggggctc    780

ttcacgttgg ccatgaacag ggccgggagc atcgtgttcc ttacggtggt ggctgcggac    840

aggtatttca aagtggtcca cccccaccac gcggtgaaca ctatctccac ccgggtggcg    900

gctggcatcg tctgcaccct gtgggccctg gtcatcctgg gaacagtgta tcttttgctg    960

gagaaccatc tctgcgtgca agagacggcc gtctcctgtg agagcttcat catggagtcg   1020

gccaatggct ggcatgacat catgttccag ctggagttct ttatgcccct cggcatcatc   1080

ttattttgct ccttcaagat tgtttggagc ctgaggcgga ggcagcagct ggccagacag   1140

gctcggatga agaaggcgac ccggttcatc atggtggtgg caattgtgtt catcacatgc   1200

tacctgccca gcgtgtctgc tagactctat ttcctctgga cggtgccctc gagtgcctgc   1260

gatccctctg tccatggggc cctgcacata accctcagct tcacctacat gaacagcatg   1320

ctggatcccc tggtgtatta tttttcaagc ccctcctttc ccaaattcta caacaagctc   1380

aaaatctgca gtctgaaacc caagcagcca ggacactcaa aaacacaaag gccggaagag   1440

atgccaattt cgaacctcgg tcgcaggagt tgcatcagtg tggcaaatag tttccaaagc   1500

cagtctgatg ggcaatggga tccccacatt gttgagtggc actgaacaag cagaccaaca   1560

acactgagga agatagagtg gtgacttaga attaactcgt gctaaggggt cgggggcttt   1620

gaaaatgcca cccccctttc ttattgcaag acggcttctc gcacatgaac tgcatccttc   1680

tcattctgtc ggaaatgaaa ttcacacaac tatacctttt ggggaggttc cagttgattg   1740

aaagagtgtt ccaaccacat cctccaggga aaatccctcg accaagagtc caatctgatt   1800

ttgcacttcc ctgacttctt gctaagccgt ctacaccagg agggtttgct gaaatgaaaa   1860

tgcgaccttt tgcaagggac atgcaagatg aaaccttcta tttccttggc agcccagagg   1920

aatcatgtgc acgatacctt aatttgctgg tgtcttttct ctgagtgggg catgagcatc   1980

agacaagcta atgcaaaagc cggaagttct aactggatat actgcctggc gactccgatc   2040

aggtcaagat cacctgagac tggacatctt cgagagagaa cattaattag ttaataatct   2100

ggcagattca ctagattata ttggcctttc tagctttcca tagtcatctg cctgtccaag   2160

ttttcaataa ttttaaacac taaagtgctg gtgcatgaca tatgcttagg aatgagtaac   2220

acaagtcttt gacagcactc tacacagaat aaaagaattt acccatggg               2269


<210>  8227
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  8227

Met Asn Cys Ile Leu Leu Ile Leu Ser Glu Met Lys Phe Thr Gln Leu 
1               5                   10                  15


Tyr Leu Leu Gly Arg Phe Gln Leu Ile Glu Arg Val Phe Gln Pro His 
            20                  25                  30


Pro Pro Gly Lys Ile Pro Arg Pro Arg Val Gln Ser Asp Phe Ala Leu 
        35                  40                  45


Pro 



<210>  8228
<211>  378
<212>  DNA
<213>  Homo sapiens

<400>  8228
tgtacagttc agtggtatgt ggccattttt taaaaatcac aaagttttta aaaagcaaga     60

tgtgcgaaat agtgtgtata aatacacaca atctatttgt agatctttcg atcttcaaat    120

gtgaaacact tataacagcc acctactccc gagctcctca gttatgtctt atcaaaacgt    180

aaagtgtttt tctcactgat tgcacattga agtattagcc ccagaagaga tataaaaaga    240

ttttcttttt ttttgagacg gagtcttgct ctgtcgccca ggctggagtg cagtggtgcg    300

atctcggctc actgcaagct ccacctcccg ggagaattgc ttgaacccag gtggcctggg    360

caacagcaag actatctc                                                  378


<210>  8229
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  8229

Met Cys Glu Ile Val Cys Ile Asn Thr His Asn Leu Phe Val Asp Leu 
1               5                   10                  15


Ser Ile Phe Lys Cys Glu Thr Leu Ile Thr Ala Thr Tyr Ser Arg Ala 
            20                  25                  30


Pro Gln Leu Cys Leu Ile Lys Thr 
        35                  40


<210>  8230
<211>  1946
<212>  DNA
<213>  Homo sapiens

<400>  8230
cagatgcaga cacagtgctg ctctttctga aaagtgtgca ggatgtttcc ttatatgtcc     60

gagaggctga cggaacagag aaactggtgt ttagagtgac ttcgagtgag agtaaggcac    120

tgaaacatga gcggccgaat tctataaaga ttctgggaac tgctataagt aactattgta    180

aaaagactcc aagcaataac atcacctgtg taacatatca cgtaaatatt gttttagaag    240

aggagagtac taaggatgca cagaaaacat cttggttggt gtgtaacagt gtgggtgggc    300

gagggatcag tagtaagctt gactctttag ctgatgaact gaaatttgtc ccaatcattg    360

gaatagccat gcctttatca agcagagatg atgaagcaaa aggagcaacg tctgatttct    420

caggaaaagc attttgtttc cttcctttac cacctggtga ggaaagcagc acaggcctcc    480

cagttcacat cagtgggttc tttggcctta ctgataaccg caggagcata aaatggagag    540

agctggacca gtggagagac ccggcagcct tatggaatga gtttcttgtc atgaatgttg    600

tccccaaagc ttatgctact ctgatcttag attcaataaa acgtctggag atggaaaaga    660

gctctgattt ccccttgtca gttgatgtta tctataagct ttggccggag gcgagcaaag    720

tcaaggtgca ctggcaaccg gtgttagagc ctctattcag cgagctgttg cagaatgcag    780

tgatttattc aattagctgt gactgggtca ggttggagca ggtgtacttc tcagaacttg    840

atgaaaattt agaatacaca aaaactgtgc tcaactacct ccagagctca gggaagcaga    900

ttgccaaggt accagggaat gtggatgctg ctgttcagct cacagctgcc tctggcacaa    960

cacctgtgag gaaggtgacg cccgcgtggg tgcggcaggt gctgcggaag tgtgcacacc   1020

tgggctgtgc tgaagaaaag cttcaccttc tagaatttgt gctttctgac caagcctaca   1080

gtgagctgct tgggctggag ctgctccctt tacaaaatgg caattttgtc cccttctcct   1140

catctgtatc agaccaagat gtcatttata ttacctcagc agaatatcca aggtcccttt   1200

tcccaagtct tgaaggaaga tttattttgg ataacttgaa acctcacctt gtggctgctt   1260

taaaggaagc tgcccaaacc cgaggcttcc tgtttgatga agatagcaac ggaaaactca   1320

aaatggtggc agttcttatt accagttgtt agtattgttt ctggaaactg cttgccaaga   1380

caacatttat taactgttag aacacttgct ttatgtttgt gtgtacatat tttccacaaa   1440

tgttataatt tatatagtgt ggttgaacag gatgcaatct tttgttgtct aaaggtgctg   1500

cagttaaaaa aaaaacaacc ttttctttca atatggcatg tagtggagtt tttttaactt   1560

taaaaacatc aaaaattgtt aaaatcattg tgttatctag tagtttataa ttatcggctt   1620

atatttcccc atgaatgatc agaactgaca tttaattcat gtttgtctcg ccatgcttct   1680

ttactttaac atatttcttt tgcagaatgt aaaaggtaat gataattagt ttatataagt   1740

gtactggctg taaatgatgc taaatatact ttatgcaatt aagggcttac agaacatgtt   1800

gaaacttttt ttacttttat tgggaataag gaatgtttgc acctccacat tttattgctt   1860

ctggatgtga aatcatgtaa ttatttctgc tgttatataa agtgccatac ttttaataaa   1920

ggaaaatgta catatgaaat catcgt                                        1946


<210>  8231
<211>  327
<212>  PRT
<213>  Homo sapiens

<400>  8231

Met Pro Leu Ser Ser Arg Asp Asp Glu Ala Lys Gly Ala Thr Ser Asp 
1               5                   10                  15


Phe Ser Gly Lys Ala Phe Cys Phe Leu Pro Leu Pro Pro Gly Glu Glu 
            20                  25                  30


Ser Ser Thr Gly Leu Pro Val His Ile Ser Gly Phe Phe Gly Leu Thr 
        35                  40                  45


Asp Asn Arg Arg Ser Ile Lys Trp Arg Glu Leu Asp Gln Trp Arg Asp 
    50                  55                  60


Pro Ala Ala Leu Trp Asn Glu Phe Leu Val Met Asn Val Val Pro Lys 
65                  70                  75                  80


Ala Tyr Ala Thr Leu Ile Leu Asp Ser Ile Lys Arg Leu Glu Met Glu 
                85                  90                  95


Lys Ser Ser Asp Phe Pro Leu Ser Val Asp Val Ile Tyr Lys Leu Trp 
            100                 105                 110


Pro Glu Ala Ser Lys Val Lys Val His Trp Gln Pro Val Leu Glu Pro 
        115                 120                 125


Leu Phe Ser Glu Leu Leu Gln Asn Ala Val Ile Tyr Ser Ile Ser Cys 
    130                 135                 140


Asp Trp Val Arg Leu Glu Gln Val Tyr Phe Ser Glu Leu Asp Glu Asn 
145                 150                 155                 160


Leu Glu Tyr Thr Lys Thr Val Leu Asn Tyr Leu Gln Ser Ser Gly Lys 
                165                 170                 175


Gln Ile Ala Lys Val Pro Gly Asn Val Asp Ala Ala Val Gln Leu Thr 
            180                 185                 190


Ala Ala Ser Gly Thr Thr Pro Val Arg Lys Val Thr Pro Ala Trp Val 
        195                 200                 205


Arg Gln Val Leu Arg Lys Cys Ala His Leu Gly Cys Ala Glu Glu Lys 
    210                 215                 220


Leu His Leu Leu Glu Phe Val Leu Ser Asp Gln Ala Tyr Ser Glu Leu 
225                 230                 235                 240


Leu Gly Leu Glu Leu Leu Pro Leu Gln Asn Gly Asn Phe Val Pro Phe 
                245                 250                 255


Ser Ser Ser Val Ser Asp Gln Asp Val Ile Tyr Ile Thr Ser Ala Glu 
            260                 265                 270


Tyr Pro Arg Ser Leu Phe Pro Ser Leu Glu Gly Arg Phe Ile Leu Asp 
        275                 280                 285


Asn Leu Lys Pro His Leu Val Ala Ala Leu Lys Glu Ala Ala Gln Thr 
    290                 295                 300


Arg Gly Phe Leu Phe Asp Glu Asp Ser Asn Gly Lys Leu Lys Met Val 
305                 310                 315                 320


Ala Val Leu Ile Thr Ser Cys 
                325


<210>  8232
<211>  14884
<212>  DNA
<213>  Homo sapiens

<400>  8232
agttatctga ctggatcaag attggagatc tgacttccaa aaattgtcat ctttttgtaa     60

accttcaatc aaaaggctta aaagggggag gtcgatttgg tcagacaacg ccaccacttg    120

ttgattttct caaggacatt ttgagaagat atccagaagg aggacagatt cttaaggaat    180

taattcagaa tgcagaagat gctggggcga cagaagttaa atttttatat gatgaaactc    240

aatacggaac agagactctt tggtcaaaag atatggcgcc atatcagggg ccagctctct    300

atgtgtacaa caacgcggtt ttcaccccag aggactggca cggcattcaa gaaatagcaa    360

gaagcaggaa aaaggatgat cctctgaagg tcggaagatt tggaattggg tttaattctg    420

tctatcatat aacagatgtt ccttgtatct ttagtggtga ccaaatcggg atgctagatc    480

ctcatcaaac actttttggc ccacatgaat caggccaatg ttggaatctc aaagatgaca    540

gcaaagaaat tagtgaactt tcagaccagt ttgcaccatt tgttggcatt tttggaagca    600

ccaaggaaac atttataaac ggcaattttc caggaacatt tttccgtttc cctcttcgcc    660

tacaaccttc acaacttagt agtaacctct acaataagca gaaggttctt gagttgtttg    720

agtcttttag ggcagatgca gacacagtgc tgctctttct gaaaagtgtg caggatgttt    780

ccttatatgt ccgagaggct gacggaacag agaaactggt gtttagagtg acttcgagtg    840

agagtaaggc actgaaacat gagcggccga attctataaa gattctggga actgctataa    900

gtaactattg taaaaagact ccaagcaata acatcacctg tgtaacatat cacgtaaata    960

ttgttttaga agaggagagt actaaggatg cacagaaaac atcttggttg gtgtgtaaca   1020

gtgtgggtgg gcgagggatc agtagtaagc ttgactcttt agctgatgaa ctgaaatttg   1080

tcccaatcat tggaatagcc atgcctttat caagcagaga tgatgaagca aaaggagcaa   1140

cgtctgattt ctcaggaaaa gcattttgtt tccttccttt accacctggt gaggaaagca   1200

gcacaggcct cccagttcac atcagtgggt tctttggcct tactgataac cgcaggagca   1260

taaaatggag agagctggac cagtggagag acccggcagc cttatggaat gagtttcttg   1320

tcatgaatgt tgtccccaaa gcttatgcta ctctgatctt agattcaata aaacgtctgg   1380

agatggaaaa gagctctgat ttccccttgt cagttgatgt tatctataag ctttggccgg   1440

aggcgagcaa agtcaaggtg cactggcaac cggtgttaga gcctctattc agcgagctgt   1500

tgcagaatgc agtgatttat tcaattagct gtgactgggt caggttggag caggtgtact   1560

tctcagaact tgatgaaaat ttagaataca caaaaactgt gctcaactac ctccagagct   1620

cagggaagca gattgccaag gtaccaggga atgtggatgc tgctgttcag ctcacagctg   1680

cctctggcac aacacctgtg aggaaggtga cgcccgcgtg ggtgcggcag gtgctgcgga   1740

agtgtgcaca cctgggctgt gctgaagaaa agcttcacct tctagaattt gtgctttctg   1800

accaagccta cagtgagctg cttgggctgg agctgctccc tttacaaaat ggcaattttg   1860

tccccttctc ctcatctgta tcagaccaag atgtcattta tattacctca gcagaatatc   1920

caaggtccct tttcccaagt cttgaaggaa gatttatttt ggataacttg aaacctcacc   1980

ttgtggctgc tttaaaggaa gctgcccaaa cccgaggaag accatgtact cagctgcagc   2040

ttctaaatcc agaacgattt gcacgtctta tcaaggaagt aatgaataca ttctggcctg   2100

gcagagaatt gattgttcaa tggtatccat ttgatgaaaa cagaaatcac ccatctgttt   2160

catggcttaa gatggtttgg aaaaatcttt atatacattt ttcagaggat ttgactttat   2220

ttgatgagat gccacttatc cccagaacta tactagagga aggtcagaca tgtgtggaac   2280

tcattagact caggattcca tcgttagtca ttttagacga tgaatctgaa gcacagcttc   2340

cagaattttt agcagacatt gtacaaaaac ttggagggtt tgtccttaaa aaattagatg   2400

catctataca acatccgctt attaaaaaat atattcattc accattacca agtgctgttt   2460

tgcagataat ggagaagatg ccattgcaga aattgtgtaa tcaaataact tcgctacttc   2520

caacacacaa agatgccctg aggaagttct tggctagttt aaccgatagc agtgagaaag   2580

agaaaagaat tattcaagaa ttggcaatat tcaagcgcat taaccattct tctgatcagg   2640

gaatttcctc ttatacaaaa ttgaaaggtt gtaaagtctt acaccatact gccaaactcc   2700

cagcagatct gcgactttct atttcagtaa tagacagtag tgatgaagct actattcgtc   2760

tggcaaacat gttgaaaata gaacagttaa agaccactag ctgcttaaag cttgttttaa   2820

aagatattga aaatgcattt tattcacatg aagaggtaac acagcttatg ttatgggtcc   2880

ttgagaatct atcttctctt aaaaatgaga atccaaatgt gcttgagtgg ttaacaccat   2940

taaaattcat ccagatatca caggaacaga tggtatcagc tggtgaactc tttgaccctg   3000

atatagaagt actaaaggat ctcttttgta atgaagaagg aacctatttc ccaccctcag   3060

tttttacctc accagatatt cttcactcct taagacagat tggtttaaaa aacgaagcca   3120

gtctcaaaga aaaggatgtt gtgcaagtgg caaaaaaaat tgaagcctta caggtcggtg   3180

cttgtcctga tcaagatgtt cttctgaaga aagccaaaac cctcttactg gttttaaata   3240

agaatcacac actgttgcaa tcatctgaag gaaagatgac attgaagaaa ataaaatggg   3300

ttccagcctg caaggaaagg cctccaaatt atccaggctc tttggtctgg aaaggagatc   3360

tctgtaatct ctgtgcacca ccagatatgt gtgatgtagg ccatgcaatt ctcattggct   3420

cctcacttcc tcttgttgaa agtatccatg taaacctgga aaaagcatta gggatcttca   3480

caaaacctag ccttagtgct gtcttaaaac actttaaaat tgttgttgat tggtattctt   3540

caaaaacctt tagtgatgaa gactactatc aattccagca tattttgctt gagatttacg   3600

gattcatgca tgatcatcta aatgaaggga aagattcttt tagagcctta aaatttccat   3660

gggtttggac tggcaaaaag ttttgtccac ttgcccaggc tgtgattaaa ccaatccatg   3720

atcttgacct tcagccttat ttgcataatg tacctaaaac catggcaaaa ttccaccaac   3780

tatttaaggt ctgtggttca atagaggagt tgacatcaga tcatatttcc atggttattc   3840

agaagatata tctcaaaagt gaccaagatc tcagtgaaca agaaagcaaa caaaatcttc   3900

atcttatgtt gaatattatc agatggctgt atagcaatca gattccagca agccccaaca   3960

caccagttcc tatacatcat agcaaaaatc cttctaaact tatcatgaag ccaattcacg   4020

aatgctgtta ttgtgacatt aaagttgatg accttaatga cttacttgaa gattctgtgg   4080

aaccaatcat tttggtgcat gaggacatac ccatgaaaac tgcagaatgg ctaaaagttc   4140

catgccttag tacaagactg ataaatcctg aaaacatggg atttgagcag tcaggacaaa   4200

gagagccact tactgtaaga attaaaaata ttctggaaga atacccttca gtgtcagata   4260

tttttaaaga actacttcaa aacgctgatg atgcaaatgc aacagaatgc agtttcttga   4320

ttgatatgag aagaaatatg gacataagag agaatctcct agacccaggg atggcagctt   4380

gtcatggacc tgctttgtgg tcattcaaca attctcaatt ctcagattca gattttgtga   4440

acataactag gttaggagaa tctttaaaaa ggggagaagt tgacaaagtt ggaaaatttg   4500

gtcttggatt taattctgtg taccatatca ctgacattcc catcattatg agtcgggaat   4560

tcatgataat gttcgatcca aacataaatc atatcagtaa acacattaaa gacaaatcca   4620

atcctgggat caaaattaat tggagtaaac aacagaaaag acttagaaaa tttcctaatc   4680

agttcaaacc atttatagat gtatttggct gtcagttacc tttgactgta gaagcacctt   4740

acagctataa tggaaccctt ttccgactgt cctttagaac tcaacaggaa gcaaaagtga   4800

gtgaagttag tagtacgtgc tacaatacag cagatattta ttctcttgtg gatgaattta   4860

gtctctgtgg acacaggctt atcattttca ctcagagtgt aaagtcaatg tatttgaagt   4920

acttgaaaat tgaggaaacc aaccccagtt tagcacaaga tacagtaata attaaaaaaa   4980

aatcctgctc ttccaaagca ttgaacacac ctgtcttaag tgttttaaaa gaggctgcta   5040

agctcatgaa gacttgcagc agcagtaata aaaagcttcc cagtgatgaa ccaaagtcat   5100

cttgcattct tcagatcaca gtggaagaat ttcaccatgt gttcagaagg attgctgatt   5160

tacagtcgcc actttttaga ggtccagatg atgacccagc tgctctcttt gaaatggcta   5220

agtctggcca atcaaaaaag ccatcagatg agttgtcaca gaaaacagta gagtgtacca   5280

cgtggcttct gtgtacttgc atggacacag gagaggctct gaagttttcc ctgagtgaga   5340

gtggaagaag actaggactg gttccatgtg gggcagtagg agttcagctg tcagaaatcc   5400

aggaccagaa gtggacagtg aaaccacaca ttggagaggt gttttgctat ttacctttac   5460

gaataaaaac aggcttgcca gttcatatca atgggtgctt tgctgttaca tcaaatagga   5520

aagaaatctg gaaaacagat acaaaaggac gatggaatac cacgttcatg agacatgtta   5580

ttgtgaaagc ttacttacag gtactgagtg tcttacggga cctggccact agtggggagc   5640

taatggatta tacttactat gcagtatggc ccgatcctga tttagttcat gatgattttt   5700

ctgtaatttg ccaaggattt tatgaagata tagctcatgg aaaagggaaa gaactgacca   5760

aagtcttctc tgatggatct acttgggttt ccatgaagaa cgtaagattt ctagatgact   5820

ctatacttaa aagaagagat gttggttcag cagccttcaa gatatttttg aaatacctca   5880

agaagactgg gtccaaaaac ctttgtgctg ttgaacttcc ttcttcggta aaattaggat   5940

ttgaagaagc tggctgcaaa cagatactac ttgaaaacac attttcagag aaacagtttt   6000

tttctgaagt gttttttcca aatattcaag aaattgaagc agaacttaga gatcctttaa   6060

tgatctttgt tctaaatgaa aaagttgatg agttctcggg agttcttcgt gttactccat   6120

gtattccttg ttccttggag gggcatcctt tggttttgcc atcaagattg atccaccccg   6180

aaggacgagt tgcaaagtta tttgatatta aagatgggag attcccttat ggttctactc   6240

aggattatct caatcctatt attttgatta aactagttca gttaggtatg gcaaaagatg   6300

atattttatg ggatgatatg ctagaacgtg cagtgtcagt agctgaaatt aataaaagtg   6360

atcatgttgc tgcatgccta agaagtagta tcttattgag tcttatcgat gagaaactaa   6420

aaataaggga tcctagagca aaggattttg ctgcaaaata tcaaacaatc cgcttccttc   6480

catttctgac aaaaccagca ggtttttctt tggactggaa aggcaacagt tttaagcctg   6540

aaaccatgtt tgcagcaact gacctttata cagctgaaca tcaagatata gtttgtcttt   6600

tgcaaccaat tctaaatgaa aattcccatt cttttagagg ttgtggttca gtgtcattgg   6660

ctgttaaaga gtttttggga ttactcaaga agccaacagt tgatctggtt ataaaccaat   6720

tgaaagaagt agcaaaatca gttgatgatg gaattacact gtaccaggag aatatcacca   6780

atgcttgcta caaatacctt catgaagcct tgatgcaaaa tgaaatcact aagatgtcaa   6840

ttattgataa gttaaaaccc tttagcttca ttctagttga gaatgcatat gttgactcag   6900

aaaaggtttc ttttcattta aattttgagg cggcaccata cctttatcag ttgcctaata   6960

agtataaaaa taatttccgc gaactttttg aaaccgtggg tgtgaggcag tcatgcactg   7020

ttgaagattt tgctcttgtt ttggaatcta ttgatcaaga aagaggaaca aagcaaataa   7080

cagaagagaa ttttcagctt tgccgacgaa taatcagtga aggaatatgg agtctcatta   7140

gagaaaagaa acaagaattt tgtgagaaaa attatggcaa gatattattg ccagatacta   7200

atcttatgct tctccctgct aaatcgttat gctacaatga ttgcccttgg ataaaagtaa   7260

aggataccac tgtaaaatat tgtcatgctg acatacccag ggaagtagca gtaaaactag   7320

gagcagtccc aaagcgacac aaagccttag aaagatatgc atccaatgtc tgttttacaa   7380

cacttggcac agaatttggg cagaaagaaa aattgaccag cagaattaag agcatcctta   7440

atgcatatcc ttctgaaaag gaaatgttga aagagcttct tcaaaatgct gatgatgcaa   7500

aggcgacaga aatctgtttt gtgtttgatc ctagacagca tccagttgat agaatatttg   7560

atgataagtg ggccccattg caagggccag cactttgtgt gtacaacaac cagccattta   7620

cagaagatga tgttagagga attcagaatc ttggaaaagg cacgaaagag ggaaatcctt   7680

ataaaactgg acagtatgga ataggattca attctgtgta tcatatcaca gactgcccat   7740

cttttatttc tggcaatgac atcctgtgta tttttgatcc tcatgccaga tatgcaccag   7800

gggccacatc cattagtccc ggacgcatgt ttagagattt ggatgcagat tttaggacac   7860

agttctcaga tgttctggat ctttatctgg gaacccattt taaactggat aattgcacaa   7920

tgttcagatt tcctcttcgt aatgcagaaa tggcaaaagt ttcggaaatt tcgtctgttc   7980

cagcatcaga cagaatggtc cagaatcttt tggacaaact gcgctcagat ggggcagaac   8040

ttctaatgtt tcttaatcac atggaaaaaa tttctatttg tgaaatagat aagagtactg   8100

gagctctaaa tgtgctgtat tcagtaaagg gcaaaatcac agatggagac agattgaaaa   8160

ggaaacaatt tcatgcatct gtaattgata gtgttactaa aaagaggcag ctcaaagaca   8220

taccagttca acaaataacc tatactatgg atactgagga ctctgaagga aatcttacta   8280

cgtggctaat ttgtaataga tcaggctttt caagtatgga gaaagtatct aaaagtgtca   8340

tatcagctca caagaaccaa gatattactc ttttcccacg tggtggagta gctgcctgca   8400

ttactcacaa ctataaaaaa ccccataggg ccttctgttt tttgcctctt tctttggaga   8460

ctgggctgcc atttcatgtg aatggccact ttgcactgga ttcagccaga aggaacctgt   8520

ggcgtgatga taatggagtt ggtgttcgaa gtgactggaa taacagttta atgacagcat   8580

taatagctcc tgcatatgtt gaattgctaa tacagttaaa aaaacggtat ttccctggtt   8640

ctgatccaac attatcagtg ttacagaaca cccctattca tgttgtaaag gacactttaa   8700

agaagttttt atcgtttttc ccagttaacc gtcttgatct acagccagat ttatattgtc   8760

tagtgaaagc actttacaat tgcattcacg aagacatgaa acgtctttta cctgttgtgc   8820

gggctccaaa tattgatggc tctgacttgc actctgcagt tataattact tggatcaata   8880

tgtctacttc taataaaact agaccatttt ttgacaattt actacaggat gaattacaac   8940

accttaaaaa tgcagattat aatatcacca cacgcaaaac agtagcagag aatgtctata   9000

ggctgaaaca tctcctttta gaaattggtt tcaacttggt ttataactgt gatgaaactg   9060

ctaatcttta ccactgtctt atagatgcag atattcctgt tagttatgtg acccctgctg   9120

atatcagatc ttttttaatg acattttcct ctcctgacac taattgccat attgggaagc   9180

tgccttgtcg tctgcagcag actaatctaa aactttttca tagtttaaaa cttttagttg   9240

attattgttt taaagatgca gaagaaaatg agattgaagt tgagggattg ccccttctca   9300

tcacactgga cagtgttttg caaacttttg atgcaaaacg acccaagttt ctaacaacat   9360

atcatgaatt gattccatcc cgcaaagact tgtttatgaa tacattatat ttgaaatata   9420

gtaatatttt attgaactgt aaagttgcaa aagtgtttga catttccagc tttgctgatt   9480

tgttatcctc tgtgttgcct cgagaatata agaccaaaag ttgcacaaag tggaaagaca   9540

attttgcaag tgagtcttgg cttaagaatg catggcattt tattagtgaa tctgtaagtg   9600

tgaaagaaga tcaggaagaa acaaaaccaa catttgacat tgttgttgat actctaaaag   9660

actgggcatt gcttccagga acaaagttta ctgtttcagc caaccagctt gtggttcctg   9720

aaggagatgt tctgcttcct ctcagcctta tgcacattgc agtttttcca aatgcccaga   9780

gtgataaagt ttttcatgct ctaatgaaag ctggctgtat tcagcttgct ttgaacaaaa   9840

tctgttccaa agacagtgca tttgttcctt tgttgtcatg tcacacagca aatatagaga   9900

gccccacaag catcttgaag gctctacatt atatggtcca aacttcaaca tttagagcag   9960

aaaaattagt agaaaatgat tttgaggcac ttttgatgta tttcaactgc aatttgaatc  10020

atttgatgtc ccaagatgat ataaaaattc taaagtcact tccgtgctat aaatccatca  10080

gtggccgcta tgtaagcatt ggaaaatttg gaacatgcta cgtacttaca aaaagtatcc  10140

cttcagctga agtggagaaa tggacacagt catcatcatc tgcatttctt gaagaaaaaa  10200

tacacttaaa agaactatat gaggtgattg gttgtgtacc tgtagatgat cttgaggtat  10260

atttgaaaca cctcttacca aaaattgaaa atctctctta tgatgcaaaa ttagagcact  10320

tgatctacct taagaataga ttatcaagtg ctgaggaatt atcagagatt aaggaacaac  10380

tttttgaaaa actggaaagt ttattgataa tccatgatgc taacagtaga ctaaagcaag  10440

caaagcattt ctatgataga actgtgagag tttttgaagt tatgcttcct gaaaaattgt  10500

ttattcctaa tgatttcttt aagaaattgg aacaacttat aaaacccaaa aatcatgtta  10560

catttatgac atcctgggtg gaattcttaa gaaatattgg actaaaatac atactttctc  10620

agcagcagtt gttacagttt gctaaggaaa tcagtgtgag ggctaataca gaaaactggt  10680

ccaaagaaac attgcaaaat acagttgata tccttctgca tcatatattc caagaacgaa  10740

tggatttgtt atctggaaat tttctgaaag aactatcttt aataccattc ttatgtcctg  10800

agcgggcccc cgcggaattc attagatttc atcctcaata tcaagaggta aatggaacac  10860

ttcctcttat aaagttcaat ggagcacagg taaatccaaa attcaagcaa tgtgatgtac  10920

tccagctgtt atggacatcc tgccctattc ttccagagaa agctacaccc ttaagcatta  10980

aagaacaaga aggtagtgac cttggtccac aagaacagct tgaacaagtt ttaaatatgc  11040

ttaatgttaa cctggatcct cctcttgata aggtaatcaa taactgcaga aacatatgca  11100

acataacgac gttggatgaa gaaatggtaa aaactagagc aaaagtctta aggagcatat  11160

atgaattcct cagtgcagaa aaaagggaat ttcgttttca gttgcgaggg gttgcttttg  11220

tgatggtaga agatggttgg aaacttctga agcctgagga ggtagtcata aacctagaat  11280

atgaatctga ttttaaacct tatttgtaca agctaccttt agaacttggc acatttcacc  11340

agttgttcaa acacttaggt actgaagata ttatttcaac taagcaatat gttgaagtgt  11400

tgagccgcat atttaaaaat tctgagggca aacaattaga tcctaatgaa atgcgtacag  11460

ttaagagagt agtttctggt ctgttcagga gtctacagaa tgattcagtc aaggtgagga  11520

gtgatctcga gaatgtacga gaccttgcgc tttacctccc aagccaggat ggtagattgg  11580

taaagtcaag catcttagtg tttgacgatg cgccacatta taaaagtaga atccagggga  11640

atattggtgt gcaaatgtta gttgatctca gccagtgcta cttagggaaa gaccatggat  11700

ttcacactaa gttgataatg ctctttcctc aaaaacttag acctcgatta ttgagcagta  11760

tacttgaaga acaattagat gaagagactc ccaaagtttg tcagtttgga gcgttgtgtt  11820

ctcttcaagg aagattgcag ttactcttgt cttctgaaca gttcattaca ggactgatta  11880

gaattatgaa gcatgaaaat gataatgctt ttctggccaa tgaagaaaaa gccataagac  11940

tttgcaaagc cctaagagaa ggattgaaag tatcctgctt tgaaaagctt caaacaacat  12000

taagagttaa aggttttaat cctattcccc acagcagaag tgaaactttt gcttttttga  12060

agcgatttgg taatgcagtc atcttgctct acattcaaca ttcagacagt aaagacatta  12120

atttcctgtt agcattggca atgactctta aatcagcaac tgacaatttg atttctgaca  12180

cttcatattt aattgctatg ctaggatgca atgatattta caggattggt gagaaacttg  12240

acagtttagg agtgaaatat gactcttcgg agccatcaaa actggaactt ccaatgcctg  12300

gcacaccaat tcctgctgaa attcattaca ctctgcttat ggacccaatg aatgtttttt  12360

acccgggaga atatgttggg taccttgttg atgctgaagg tggtgatatc tatggatcat  12420

accagccaac atacacatat gcaattattg tacaagaagt tgaaagagaa gatgctgaca  12480

attctagttt tctaggaaag atatatcaga tagatattgg ttatagtgaa tataaaatag  12540

ttagctctct tgatctgtat aagttttcaa gacctgagga aagctctcaa agcagggaca  12600

gtgctccttc tacaccaacc agccccactg agttcctcac ccctggcctg agaagcattc  12660

ctcctctttt ctctggtaga gagagccaca agacttcttc caaacatcag tcccccaaaa  12720

agcttaaggt taattcttta ccagaaatct taaaagaagt gacatctgtg gtggagcaag  12780

catggaagct tccagaatcg gaacgaaaaa agattattag gcggttgtat ttgaaatggc  12840

atcctgacaa aaatccagag aaccatgaca ttgccaatga agtttttaaa catttgcaga  12900

atgaaatcaa cagattagaa aaacaggctt ttctagatca aaatgcagac agggcctcca  12960

gacgaacatt ttcaacctca gcatcccgat ttcagtcaga caaatactca tttcagagat  13020

tctatacttc atggaatcaa gaagcaacga gccataaatc tgaaagacag caacagaaca  13080

aagaaaaatg ccccccttca gccggacaga cttactctca aaggttcttt gttcctccca  13140

ctttcaagtc ggttggcaat ccagtggaag cacgcagatg gctaagacaa gccagagcaa  13200

acttctcagc tgccaggaat gaccttcata aaaatgccaa tgagtgggtg tgctttaaat  13260

gttacctttc taccaagtta gctttgattg cagctgacta tgctgtgagg ggaaagtctg  13320

ataaagatgt aaaaccaact gcacttgctc agaaaataga ggaatatagt cagcaacttg  13380

aaggactgac aaatgatgtt cacacattgg aagcttatgg tgtagacagt ttaaaaacaa  13440

gataccctga tttgcttccc tttcctcaga tcccaaatga caggttcact tctgaggttg  13500

ctatgagggt gatggaatgt actgcctgta tcataataaa acttgaaaat tttatgcaac  13560

aaaaagtgtg aagatattta acgaaaaaaa aggtagatct tgaatgtgtt gtagcacgaa  13620

taaattgctg tacttcatta agcttcattg ccaattagct aggaattgtt aagcacattg  13680

cagattgttc ttggagaatt ctggagttgt tatgaacatg aataccaacg gaaaacctta  13740

actgaatcta aaagaaaact attttgaaga tggtggtgag ctgcaaaata gctggatgga  13800

tttgaatgat tgggatgata catcattgaa ctgcacttta tataaccaaa gcttagcagt  13860

ttgttagata agagtctatg tatgtctctg gttaggatga agttaatttt atgtttttaa  13920

catggtattt ttgaaggagc taatgaaaca ctggacatat aattggttta aacataaggg  13980

gaattaagtc tttgtagtct gtcatttttt taagtggatc ctcttggatg cgttattttc  14040

tcatcagctg gctctgatca tgaatttgtt gtaattttat gttgtactca gtgcatttaa  14100

gaaatggtag agtattttaa tcctattact tgactaagag tgtgaaggta gtacttttta  14160

gagtgcactg agtgcacttt acatctttat ttaaattttt ttttaacatc ttatgtttac  14220

aggcttcctg tttgatgaag atagcaacgg aaaactcaaa atggtggcag ttcttattac  14280

cagttgttag tattgtttct ggaaactgct tgccaagaca acatttatta actgttagaa  14340

cacttgcttt atgtttgtgt gtacatattt tccacaaatg ttataattta tatagtgtgg  14400

ttgaacagga tgcaatcttt tgttgtctaa aggtgctgca gttaaaaaaa aaacaacctt  14460

ttctttcaat atggcatgta gtggagtttt tttaacttta aaaacatcaa aaattgttaa  14520

aatcattgtg ttatctagta gtttataatt atcggcttat atttccccat gaatgatcag  14580

aactgacatt taattcatgt ttgtctcgcc atgcttcttt actttaacat atttcttttg  14640

cagaatgtaa aaggtaatga taattagttt atataagtgt actggctgta aatgatgcta  14700

aatatacttt atgcaattaa gggcttacag aacatgttga aacttttttt acttttattg  14760

ggaataagga atgtttgcac ctccacattt tattgcttct ggatgtgaaa tcatgtaatt  14820

atttctgctg ttatataaag tgccatactt ttaataaagg aaaatgtaca tatgaaatca  14880

tcgt                                                               14884


<210>  8233
<211>  4432
<212>  PRT
<213>  Homo sapiens

<400>  8233

Met Ala Pro Tyr Gln Gly Pro Ala Leu Tyr Val Tyr Asn Asn Ala Val 
1               5                   10                  15


Phe Thr Pro Glu Asp Trp His Gly Ile Gln Glu Ile Ala Arg Ser Arg 
            20                  25                  30


Lys Lys Asp Asp Pro Leu Lys Val Gly Arg Phe Gly Ile Gly Phe Asn 
        35                  40                  45


Ser Val Tyr His Ile Thr Asp Val Pro Cys Ile Phe Ser Gly Asp Gln 
    50                  55                  60


Ile Gly Met Leu Asp Pro His Gln Thr Leu Phe Gly Pro His Glu Ser 
65                  70                  75                  80


Gly Gln Cys Trp Asn Leu Lys Asp Asp Ser Lys Glu Ile Ser Glu Leu 
                85                  90                  95


Ser Asp Gln Phe Ala Pro Phe Val Gly Ile Phe Gly Ser Thr Lys Glu 
            100                 105                 110


Thr Phe Ile Asn Gly Asn Phe Pro Gly Thr Phe Phe Arg Phe Pro Leu 
        115                 120                 125


Arg Leu Gln Pro Ser Gln Leu Ser Ser Asn Leu Tyr Asn Lys Gln Lys 
    130                 135                 140


Val Leu Glu Leu Phe Glu Ser Phe Arg Ala Asp Ala Asp Thr Val Leu 
145                 150                 155                 160


Leu Phe Leu Lys Ser Val Gln Asp Val Ser Leu Tyr Val Arg Glu Ala 
                165                 170                 175


Asp Gly Thr Glu Lys Leu Val Phe Arg Val Thr Ser Ser Glu Ser Lys 
            180                 185                 190


Ala Leu Lys His Glu Arg Pro Asn Ser Ile Lys Ile Leu Gly Thr Ala 
        195                 200                 205


Ile Ser Asn Tyr Cys Lys Lys Thr Pro Ser Asn Asn Ile Thr Cys Val 
    210                 215                 220


Thr Tyr His Val Asn Ile Val Leu Glu Glu Glu Ser Thr Lys Asp Ala 
225                 230                 235                 240


Gln Lys Thr Ser Trp Leu Val Cys Asn Ser Val Gly Gly Arg Gly Ile 
                245                 250                 255


Ser Ser Lys Leu Asp Ser Leu Ala Asp Glu Leu Lys Phe Val Pro Ile 
            260                 265                 270


Ile Gly Ile Ala Met Pro Leu Ser Ser Arg Asp Asp Glu Ala Lys Gly 
        275                 280                 285


Ala Thr Ser Asp Phe Ser Gly Lys Ala Phe Cys Phe Leu Pro Leu Pro 
    290                 295                 300


Pro Gly Glu Glu Ser Ser Thr Gly Leu Pro Val His Ile Ser Gly Phe 
305                 310                 315                 320


Phe Gly Leu Thr Asp Asn Arg Arg Ser Ile Lys Trp Arg Glu Leu Asp 
                325                 330                 335


Gln Trp Arg Asp Pro Ala Ala Leu Trp Asn Glu Phe Leu Val Met Asn 
            340                 345                 350


Val Val Pro Lys Ala Tyr Ala Thr Leu Ile Leu Asp Ser Ile Lys Arg 
        355                 360                 365


Leu Glu Met Glu Lys Ser Ser Asp Phe Pro Leu Ser Val Asp Val Ile 
    370                 375                 380


Tyr Lys Leu Trp Pro Glu Ala Ser Lys Val Lys Val His Trp Gln Pro 
385                 390                 395                 400


Val Leu Glu Pro Leu Phe Ser Glu Leu Leu Gln Asn Ala Val Ile Tyr 
                405                 410                 415


Ser Ile Ser Cys Asp Trp Val Arg Leu Glu Gln Val Tyr Phe Ser Glu 
            420                 425                 430


Leu Asp Glu Asn Leu Glu Tyr Thr Lys Thr Val Leu Asn Tyr Leu Gln 
        435                 440                 445


Ser Ser Gly Lys Gln Ile Ala Lys Val Pro Gly Asn Val Asp Ala Ala 
    450                 455                 460


Val Gln Leu Thr Ala Ala Ser Gly Thr Thr Pro Val Arg Lys Val Thr 
465                 470                 475                 480


Pro Ala Trp Val Arg Gln Val Leu Arg Lys Cys Ala His Leu Gly Cys 
                485                 490                 495


Ala Glu Glu Lys Leu His Leu Leu Glu Phe Val Leu Ser Asp Gln Ala 
            500                 505                 510


Tyr Ser Glu Leu Leu Gly Leu Glu Leu Leu Pro Leu Gln Asn Gly Asn 
        515                 520                 525


Phe Val Pro Phe Ser Ser Ser Val Ser Asp Gln Asp Val Ile Tyr Ile 
    530                 535                 540


Thr Ser Ala Glu Tyr Pro Arg Ser Leu Phe Pro Ser Leu Glu Gly Arg 
545                 550                 555                 560


Phe Ile Leu Asp Asn Leu Lys Pro His Leu Val Ala Ala Leu Lys Glu 
                565                 570                 575


Ala Ala Gln Thr Arg Gly Arg Pro Cys Thr Gln Leu Gln Leu Leu Asn 
            580                 585                 590


Pro Glu Arg Phe Ala Arg Leu Ile Lys Glu Val Met Asn Thr Phe Trp 
        595                 600                 605


Pro Gly Arg Glu Leu Ile Val Gln Trp Tyr Pro Phe Asp Glu Asn Arg 
    610                 615                 620


Asn His Pro Ser Val Ser Trp Leu Lys Met Val Trp Lys Asn Leu Tyr 
625                 630                 635                 640


Ile His Phe Ser Glu Asp Leu Thr Leu Phe Asp Glu Met Pro Leu Ile 
                645                 650                 655


Pro Arg Thr Ile Leu Glu Glu Gly Gln Thr Cys Val Glu Leu Ile Arg 
            660                 665                 670


Leu Arg Ile Pro Ser Leu Val Ile Leu Asp Asp Glu Ser Glu Ala Gln 
        675                 680                 685


Leu Pro Glu Phe Leu Ala Asp Ile Val Gln Lys Leu Gly Gly Phe Val 
    690                 695                 700


Leu Lys Lys Leu Asp Ala Ser Ile Gln His Pro Leu Ile Lys Lys Tyr 
705                 710                 715                 720


Ile His Ser Pro Leu Pro Ser Ala Val Leu Gln Ile Met Glu Lys Met 
                725                 730                 735


Pro Leu Gln Lys Leu Cys Asn Gln Ile Thr Ser Leu Leu Pro Thr His 
            740                 745                 750


Lys Asp Ala Leu Arg Lys Phe Leu Ala Ser Leu Thr Asp Ser Ser Glu 
        755                 760                 765


Lys Glu Lys Arg Ile Ile Gln Glu Leu Ala Ile Phe Lys Arg Ile Asn 
    770                 775                 780


His Ser Ser Asp Gln Gly Ile Ser Ser Tyr Thr Lys Leu Lys Gly Cys 
785                 790                 795                 800


Lys Val Leu His His Thr Ala Lys Leu Pro Ala Asp Leu Arg Leu Ser 
                805                 810                 815


Ile Ser Val Ile Asp Ser Ser Asp Glu Ala Thr Ile Arg Leu Ala Asn 
            820                 825                 830


Met Leu Lys Ile Glu Gln Leu Lys Thr Thr Ser Cys Leu Lys Leu Val 
        835                 840                 845


Leu Lys Asp Ile Glu Asn Ala Phe Tyr Ser His Glu Glu Val Thr Gln 
    850                 855                 860


Leu Met Leu Trp Val Leu Glu Asn Leu Ser Ser Leu Lys Asn Glu Asn 
865                 870                 875                 880


Pro Asn Val Leu Glu Trp Leu Thr Pro Leu Lys Phe Ile Gln Ile Ser 
                885                 890                 895


Gln Glu Gln Met Val Ser Ala Gly Glu Leu Phe Asp Pro Asp Ile Glu 
            900                 905                 910


Val Leu Lys Asp Leu Phe Cys Asn Glu Glu Gly Thr Tyr Phe Pro Pro 
        915                 920                 925


Ser Val Phe Thr Ser Pro Asp Ile Leu His Ser Leu Arg Gln Ile Gly 
    930                 935                 940


Leu Lys Asn Glu Ala Ser Leu Lys Glu Lys Asp Val Val Gln Val Ala 
945                 950                 955                 960


Lys Lys Ile Glu Ala Leu Gln Val Gly Ala Cys Pro Asp Gln Asp Val 
                965                 970                 975


Leu Leu Lys Lys Ala Lys Thr Leu Leu Leu Val Leu Asn Lys Asn His 
            980                 985                 990


Thr Leu Leu Gln Ser Ser Glu Gly Lys Met Thr Leu Lys Lys Ile Lys 
        995                 1000                1005


Trp Val Pro Ala Cys Lys Glu Arg Pro Pro Asn Tyr Pro Gly Ser Leu 
    1010                1015                1020


Val Trp Lys Gly Asp Leu Cys Asn Leu Cys Ala Pro Pro Asp Met Cys 
1025                1030                1035                1040


Asp Val Gly His Ala Ile Leu Ile Gly Ser Ser Leu Pro Leu Val Glu 
                1045                1050                1055


Ser Ile His Val Asn Leu Glu Lys Ala Leu Gly Ile Phe Thr Lys Pro 
            1060                1065                1070


Ser Leu Ser Ala Val Leu Lys His Phe Lys Ile Val Val Asp Trp Tyr 
        1075                1080                1085


Ser Ser Lys Thr Phe Ser Asp Glu Asp Tyr Tyr Gln Phe Gln His Ile 
    1090                1095                1100


Leu Leu Glu Ile Tyr Gly Phe Met His Asp His Leu Asn Glu Gly Lys 
1105                1110                1115                1120


Asp Ser Phe Arg Ala Leu Lys Phe Pro Trp Val Trp Thr Gly Lys Lys 
                1125                1130                1135


Phe Cys Pro Leu Ala Gln Ala Val Ile Lys Pro Ile His Asp Leu Asp 
            1140                1145                1150


Leu Gln Pro Tyr Leu His Asn Val Pro Lys Thr Met Ala Lys Phe His 
        1155                1160                1165


Gln Leu Phe Lys Val Cys Gly Ser Ile Glu Glu Leu Thr Ser Asp His 
    1170                1175                1180


Ile Ser Met Val Ile Gln Lys Ile Tyr Leu Lys Ser Asp Gln Asp Leu 
1185                1190                1195                1200


Ser Glu Gln Glu Ser Lys Gln Asn Leu His Leu Met Leu Asn Ile Ile 
                1205                1210                1215


Arg Trp Leu Tyr Ser Asn Gln Ile Pro Ala Ser Pro Asn Thr Pro Val 
            1220                1225                1230


Pro Ile His His Ser Lys Asn Pro Ser Lys Leu Ile Met Lys Pro Ile 
        1235                1240                1245


His Glu Cys Cys Tyr Cys Asp Ile Lys Val Asp Asp Leu Asn Asp Leu 
    1250                1255                1260


Leu Glu Asp Ser Val Glu Pro Ile Ile Leu Val His Glu Asp Ile Pro 
1265                1270                1275                1280


Met Lys Thr Ala Glu Trp Leu Lys Val Pro Cys Leu Ser Thr Arg Leu 
                1285                1290                1295


Ile Asn Pro Glu Asn Met Gly Phe Glu Gln Ser Gly Gln Arg Glu Pro 
            1300                1305                1310


Leu Thr Val Arg Ile Lys Asn Ile Leu Glu Glu Tyr Pro Ser Val Ser 
        1315                1320                1325


Asp Ile Phe Lys Glu Leu Leu Gln Asn Ala Asp Asp Ala Asn Ala Thr 
    1330                1335                1340


Glu Cys Ser Phe Leu Ile Asp Met Arg Arg Asn Met Asp Ile Arg Glu 
1345                1350                1355                1360


Asn Leu Leu Asp Pro Gly Met Ala Ala Cys His Gly Pro Ala Leu Trp 
                1365                1370                1375


Ser Phe Asn Asn Ser Gln Phe Ser Asp Ser Asp Phe Val Asn Ile Thr 
            1380                1385                1390


Arg Leu Gly Glu Ser Leu Lys Arg Gly Glu Val Asp Lys Val Gly Lys 
        1395                1400                1405


Phe Gly Leu Gly Phe Asn Ser Val Tyr His Ile Thr Asp Ile Pro Ile 
    1410                1415                1420


Ile Met Ser Arg Glu Phe Met Ile Met Phe Asp Pro Asn Ile Asn His 
1425                1430                1435                1440


Ile Ser Lys His Ile Lys Asp Lys Ser Asn Pro Gly Ile Lys Ile Asn 
                1445                1450                1455


Trp Ser Lys Gln Gln Lys Arg Leu Arg Lys Phe Pro Asn Gln Phe Lys 
            1460                1465                1470


Pro Phe Ile Asp Val Phe Gly Cys Gln Leu Pro Leu Thr Val Glu Ala 
        1475                1480                1485


Pro Tyr Ser Tyr Asn Gly Thr Leu Phe Arg Leu Ser Phe Arg Thr Gln 
    1490                1495                1500


Gln Glu Ala Lys Val Ser Glu Val Ser Ser Thr Cys Tyr Asn Thr Ala 
1505                1510                1515                1520


Asp Ile Tyr Ser Leu Val Asp Glu Phe Ser Leu Cys Gly His Arg Leu 
                1525                1530                1535


Ile Ile Phe Thr Gln Ser Val Lys Ser Met Tyr Leu Lys Tyr Leu Lys 
            1540                1545                1550


Ile Glu Glu Thr Asn Pro Ser Leu Ala Gln Asp Thr Val Ile Ile Lys 
        1555                1560                1565


Lys Lys Ser Cys Ser Ser Lys Ala Leu Asn Thr Pro Val Leu Ser Val 
    1570                1575                1580


Leu Lys Glu Ala Ala Lys Leu Met Lys Thr Cys Ser Ser Ser Asn Lys 
1585                1590                1595                1600


Lys Leu Pro Ser Asp Glu Pro Lys Ser Ser Cys Ile Leu Gln Ile Thr 
                1605                1610                1615


Val Glu Glu Phe His His Val Phe Arg Arg Ile Ala Asp Leu Gln Ser 
            1620                1625                1630


Pro Leu Phe Arg Gly Pro Asp Asp Asp Pro Ala Ala Leu Phe Glu Met 
        1635                1640                1645


Ala Lys Ser Gly Gln Ser Lys Lys Pro Ser Asp Glu Leu Ser Gln Lys 
    1650                1655                1660


Thr Val Glu Cys Thr Thr Trp Leu Leu Cys Thr Cys Met Asp Thr Gly 
1665                1670                1675                1680


Glu Ala Leu Lys Phe Ser Leu Ser Glu Ser Gly Arg Arg Leu Gly Leu 
                1685                1690                1695


Val Pro Cys Gly Ala Val Gly Val Gln Leu Ser Glu Ile Gln Asp Gln 
            1700                1705                1710


Lys Trp Thr Val Lys Pro His Ile Gly Glu Val Phe Cys Tyr Leu Pro 
        1715                1720                1725


Leu Arg Ile Lys Thr Gly Leu Pro Val His Ile Asn Gly Cys Phe Ala 
    1730                1735                1740


Val Thr Ser Asn Arg Lys Glu Ile Trp Lys Thr Asp Thr Lys Gly Arg 
1745                1750                1755                1760


Trp Asn Thr Thr Phe Met Arg His Val Ile Val Lys Ala Tyr Leu Gln 
                1765                1770                1775


Val Leu Ser Val Leu Arg Asp Leu Ala Thr Ser Gly Glu Leu Met Asp 
            1780                1785                1790


Tyr Thr Tyr Tyr Ala Val Trp Pro Asp Pro Asp Leu Val His Asp Asp 
        1795                1800                1805


Phe Ser Val Ile Cys Gln Gly Phe Tyr Glu Asp Ile Ala His Gly Lys 
    1810                1815                1820


Gly Lys Glu Leu Thr Lys Val Phe Ser Asp Gly Ser Thr Trp Val Ser 
1825                1830                1835                1840


Met Lys Asn Val Arg Phe Leu Asp Asp Ser Ile Leu Lys Arg Arg Asp 
                1845                1850                1855


Val Gly Ser Ala Ala Phe Lys Ile Phe Leu Lys Tyr Leu Lys Lys Thr 
            1860                1865                1870


Gly Ser Lys Asn Leu Cys Ala Val Glu Leu Pro Ser Ser Val Lys Leu 
        1875                1880                1885


Gly Phe Glu Glu Ala Gly Cys Lys Gln Ile Leu Leu Glu Asn Thr Phe 
    1890                1895                1900


Ser Glu Lys Gln Phe Phe Ser Glu Val Phe Phe Pro Asn Ile Gln Glu 
1905                1910                1915                1920


Ile Glu Ala Glu Leu Arg Asp Pro Leu Met Ile Phe Val Leu Asn Glu 
                1925                1930                1935


Lys Val Asp Glu Phe Ser Gly Val Leu Arg Val Thr Pro Cys Ile Pro 
            1940                1945                1950


Cys Ser Leu Glu Gly His Pro Leu Val Leu Pro Ser Arg Leu Ile His 
        1955                1960                1965


Pro Glu Gly Arg Val Ala Lys Leu Phe Asp Ile Lys Asp Gly Arg Phe 
    1970                1975                1980


Pro Tyr Gly Ser Thr Gln Asp Tyr Leu Asn Pro Ile Ile Leu Ile Lys 
1985                1990                1995                2000


Leu Val Gln Leu Gly Met Ala Lys Asp Asp Ile Leu Trp Asp Asp Met 
                2005                2010                2015


Leu Glu Arg Ala Val Ser Val Ala Glu Ile Asn Lys Ser Asp His Val 
            2020                2025                2030


Ala Ala Cys Leu Arg Ser Ser Ile Leu Leu Ser Leu Ile Asp Glu Lys 
        2035                2040                2045


Leu Lys Ile Arg Asp Pro Arg Ala Lys Asp Phe Ala Ala Lys Tyr Gln 
    2050                2055                2060


Thr Ile Arg Phe Leu Pro Phe Leu Thr Lys Pro Ala Gly Phe Ser Leu 
2065                2070                2075                2080


Asp Trp Lys Gly Asn Ser Phe Lys Pro Glu Thr Met Phe Ala Ala Thr 
                2085                2090                2095


Asp Leu Tyr Thr Ala Glu His Gln Asp Ile Val Cys Leu Leu Gln Pro 
            2100                2105                2110


Ile Leu Asn Glu Asn Ser His Ser Phe Arg Gly Cys Gly Ser Val Ser 
        2115                2120                2125


Leu Ala Val Lys Glu Phe Leu Gly Leu Leu Lys Lys Pro Thr Val Asp 
    2130                2135                2140


Leu Val Ile Asn Gln Leu Lys Glu Val Ala Lys Ser Val Asp Asp Gly 
2145                2150                2155                2160


Ile Thr Leu Tyr Gln Glu Asn Ile Thr Asn Ala Cys Tyr Lys Tyr Leu 
                2165                2170                2175


His Glu Ala Leu Met Gln Asn Glu Ile Thr Lys Met Ser Ile Ile Asp 
            2180                2185                2190


Lys Leu Lys Pro Phe Ser Phe Ile Leu Val Glu Asn Ala Tyr Val Asp 
        2195                2200                2205


Ser Glu Lys Val Ser Phe His Leu Asn Phe Glu Ala Ala Pro Tyr Leu 
    2210                2215                2220


Tyr Gln Leu Pro Asn Lys Tyr Lys Asn Asn Phe Arg Glu Leu Phe Glu 
2225                2230                2235                2240


Thr Val Gly Val Arg Gln Ser Cys Thr Val Glu Asp Phe Ala Leu Val 
                2245                2250                2255


Leu Glu Ser Ile Asp Gln Glu Arg Gly Thr Lys Gln Ile Thr Glu Glu 
            2260                2265                2270


Asn Phe Gln Leu Cys Arg Arg Ile Ile Ser Glu Gly Ile Trp Ser Leu 
        2275                2280                2285


Ile Arg Glu Lys Lys Gln Glu Phe Cys Glu Lys Asn Tyr Gly Lys Ile 
    2290                2295                2300


Leu Leu Pro Asp Thr Asn Leu Met Leu Leu Pro Ala Lys Ser Leu Cys 
2305                2310                2315                2320


Tyr Asn Asp Cys Pro Trp Ile Lys Val Lys Asp Thr Thr Val Lys Tyr 
                2325                2330                2335


Cys His Ala Asp Ile Pro Arg Glu Val Ala Val Lys Leu Gly Ala Val 
            2340                2345                2350


Pro Lys Arg His Lys Ala Leu Glu Arg Tyr Ala Ser Asn Val Cys Phe 
        2355                2360                2365


Thr Thr Leu Gly Thr Glu Phe Gly Gln Lys Glu Lys Leu Thr Ser Arg 
    2370                2375                2380


Ile Lys Ser Ile Leu Asn Ala Tyr Pro Ser Glu Lys Glu Met Leu Lys 
2385                2390                2395                2400


Glu Leu Leu Gln Asn Ala Asp Asp Ala Lys Ala Thr Glu Ile Cys Phe 
                2405                2410                2415


Val Phe Asp Pro Arg Gln His Pro Val Asp Arg Ile Phe Asp Asp Lys 
            2420                2425                2430


Trp Ala Pro Leu Gln Gly Pro Ala Leu Cys Val Tyr Asn Asn Gln Pro 
        2435                2440                2445


Phe Thr Glu Asp Asp Val Arg Gly Ile Gln Asn Leu Gly Lys Gly Thr 
    2450                2455                2460


Lys Glu Gly Asn Pro Tyr Lys Thr Gly Gln Tyr Gly Ile Gly Phe Asn 
2465                2470                2475                2480


Ser Val Tyr His Ile Thr Asp Cys Pro Ser Phe Ile Ser Gly Asn Asp 
                2485                2490                2495


Ile Leu Cys Ile Phe Asp Pro His Ala Arg Tyr Ala Pro Gly Ala Thr 
            2500                2505                2510


Ser Ile Ser Pro Gly Arg Met Phe Arg Asp Leu Asp Ala Asp Phe Arg 
        2515                2520                2525


Thr Gln Phe Ser Asp Val Leu Asp Leu Tyr Leu Gly Thr His Phe Lys 
    2530                2535                2540


Leu Asp Asn Cys Thr Met Phe Arg Phe Pro Leu Arg Asn Ala Glu Met 
2545                2550                2555                2560


Ala Lys Val Ser Glu Ile Ser Ser Val Pro Ala Ser Asp Arg Met Val 
                2565                2570                2575


Gln Asn Leu Leu Asp Lys Leu Arg Ser Asp Gly Ala Glu Leu Leu Met 
            2580                2585                2590


Phe Leu Asn His Met Glu Lys Ile Ser Ile Cys Glu Ile Asp Lys Ser 
        2595                2600                2605


Thr Gly Ala Leu Asn Val Leu Tyr Ser Val Lys Gly Lys Ile Thr Asp 
    2610                2615                2620


Gly Asp Arg Leu Lys Arg Lys Gln Phe His Ala Ser Val Ile Asp Ser 
2625                2630                2635                2640


Val Thr Lys Lys Arg Gln Leu Lys Asp Ile Pro Val Gln Gln Ile Thr 
                2645                2650                2655


Tyr Thr Met Asp Thr Glu Asp Ser Glu Gly Asn Leu Thr Thr Trp Leu 
            2660                2665                2670


Ile Cys Asn Arg Ser Gly Phe Ser Ser Met Glu Lys Val Ser Lys Ser 
        2675                2680                2685


Val Ile Ser Ala His Lys Asn Gln Asp Ile Thr Leu Phe Pro Arg Gly 
    2690                2695                2700


Gly Val Ala Ala Cys Ile Thr His Asn Tyr Lys Lys Pro His Arg Ala 
2705                2710                2715                2720


Phe Cys Phe Leu Pro Leu Ser Leu Glu Thr Gly Leu Pro Phe His Val 
                2725                2730                2735


Asn Gly His Phe Ala Leu Asp Ser Ala Arg Arg Asn Leu Trp Arg Asp 
            2740                2745                2750


Asp Asn Gly Val Gly Val Arg Ser Asp Trp Asn Asn Ser Leu Met Thr 
        2755                2760                2765


Ala Leu Ile Ala Pro Ala Tyr Val Glu Leu Leu Ile Gln Leu Lys Lys 
    2770                2775                2780


Arg Tyr Phe Pro Gly Ser Asp Pro Thr Leu Ser Val Leu Gln Asn Thr 
2785                2790                2795                2800


Pro Ile His Val Val Lys Asp Thr Leu Lys Lys Phe Leu Ser Phe Phe 
                2805                2810                2815


Pro Val Asn Arg Leu Asp Leu Gln Pro Asp Leu Tyr Cys Leu Val Lys 
            2820                2825                2830


Ala Leu Tyr Asn Cys Ile His Glu Asp Met Lys Arg Leu Leu Pro Val 
        2835                2840                2845


Val Arg Ala Pro Asn Ile Asp Gly Ser Asp Leu His Ser Ala Val Ile 
    2850                2855                2860


Ile Thr Trp Ile Asn Met Ser Thr Ser Asn Lys Thr Arg Pro Phe Phe 
2865                2870                2875                2880


Asp Asn Leu Leu Gln Asp Glu Leu Gln His Leu Lys Asn Ala Asp Tyr 
                2885                2890                2895


Asn Ile Thr Thr Arg Lys Thr Val Ala Glu Asn Val Tyr Arg Leu Lys 
            2900                2905                2910


His Leu Leu Leu Glu Ile Gly Phe Asn Leu Val Tyr Asn Cys Asp Glu 
        2915                2920                2925


Thr Ala Asn Leu Tyr His Cys Leu Ile Asp Ala Asp Ile Pro Val Ser 
    2930                2935                2940


Tyr Val Thr Pro Ala Asp Ile Arg Ser Phe Leu Met Thr Phe Ser Ser 
2945                2950                2955                2960


Pro Asp Thr Asn Cys His Ile Gly Lys Leu Pro Cys Arg Leu Gln Gln 
                2965                2970                2975


Thr Asn Leu Lys Leu Phe His Ser Leu Lys Leu Leu Val Asp Tyr Cys 
            2980                2985                2990


Phe Lys Asp Ala Glu Glu Asn Glu Ile Glu Val Glu Gly Leu Pro Leu 
        2995                3000                3005


Leu Ile Thr Leu Asp Ser Val Leu Gln Thr Phe Asp Ala Lys Arg Pro 
    3010                3015                3020


Lys Phe Leu Thr Thr Tyr His Glu Leu Ile Pro Ser Arg Lys Asp Leu 
3025                3030                3035                3040


Phe Met Asn Thr Leu Tyr Leu Lys Tyr Ser Asn Ile Leu Leu Asn Cys 
                3045                3050                3055


Lys Val Ala Lys Val Phe Asp Ile Ser Ser Phe Ala Asp Leu Leu Ser 
            3060                3065                3070


Ser Val Leu Pro Arg Glu Tyr Lys Thr Lys Ser Cys Thr Lys Trp Lys 
        3075                3080                3085


Asp Asn Phe Ala Ser Glu Ser Trp Leu Lys Asn Ala Trp His Phe Ile 
    3090                3095                3100


Ser Glu Ser Val Ser Val Lys Glu Asp Gln Glu Glu Thr Lys Pro Thr 
3105                3110                3115                3120


Phe Asp Ile Val Val Asp Thr Leu Lys Asp Trp Ala Leu Leu Pro Gly 
                3125                3130                3135


Thr Lys Phe Thr Val Ser Ala Asn Gln Leu Val Val Pro Glu Gly Asp 
            3140                3145                3150


Val Leu Leu Pro Leu Ser Leu Met His Ile Ala Val Phe Pro Asn Ala 
        3155                3160                3165


Gln Ser Asp Lys Val Phe His Ala Leu Met Lys Ala Gly Cys Ile Gln 
    3170                3175                3180


Leu Ala Leu Asn Lys Ile Cys Ser Lys Asp Ser Ala Phe Val Pro Leu 
3185                3190                3195                3200


Leu Ser Cys His Thr Ala Asn Ile Glu Ser Pro Thr Ser Ile Leu Lys 
                3205                3210                3215


Ala Leu His Tyr Met Val Gln Thr Ser Thr Phe Arg Ala Glu Lys Leu 
            3220                3225                3230


Val Glu Asn Asp Phe Glu Ala Leu Leu Met Tyr Phe Asn Cys Asn Leu 
        3235                3240                3245


Asn His Leu Met Ser Gln Asp Asp Ile Lys Ile Leu Lys Ser Leu Pro 
    3250                3255                3260


Cys Tyr Lys Ser Ile Ser Gly Arg Tyr Val Ser Ile Gly Lys Phe Gly 
3265                3270                3275                3280


Thr Cys Tyr Val Leu Thr Lys Ser Ile Pro Ser Ala Glu Val Glu Lys 
                3285                3290                3295


Trp Thr Gln Ser Ser Ser Ser Ala Phe Leu Glu Glu Lys Ile His Leu 
            3300                3305                3310


Lys Glu Leu Tyr Glu Val Ile Gly Cys Val Pro Val Asp Asp Leu Glu 
        3315                3320                3325


Val Tyr Leu Lys His Leu Leu Pro Lys Ile Glu Asn Leu Ser Tyr Asp 
    3330                3335                3340


Ala Lys Leu Glu His Leu Ile Tyr Leu Lys Asn Arg Leu Ser Ser Ala 
3345                3350                3355                3360


Glu Glu Leu Ser Glu Ile Lys Glu Gln Leu Phe Glu Lys Leu Glu Ser 
                3365                3370                3375


Leu Leu Ile Ile His Asp Ala Asn Ser Arg Leu Lys Gln Ala Lys His 
            3380                3385                3390


Phe Tyr Asp Arg Thr Val Arg Val Phe Glu Val Met Leu Pro Glu Lys 
        3395                3400                3405


Leu Phe Ile Pro Asn Asp Phe Phe Lys Lys Leu Glu Gln Leu Ile Lys 
    3410                3415                3420


Pro Lys Asn His Val Thr Phe Met Thr Ser Trp Val Glu Phe Leu Arg 
3425                3430                3435                3440


Asn Ile Gly Leu Lys Tyr Ile Leu Ser Gln Gln Gln Leu Leu Gln Phe 
                3445                3450                3455


Ala Lys Glu Ile Ser Val Arg Ala Asn Thr Glu Asn Trp Ser Lys Glu 
            3460                3465                3470


Thr Leu Gln Asn Thr Val Asp Ile Leu Leu His His Ile Phe Gln Glu 
        3475                3480                3485


Arg Met Asp Leu Leu Ser Gly Asn Phe Leu Lys Glu Leu Ser Leu Ile 
    3490                3495                3500


Pro Phe Leu Cys Pro Glu Arg Ala Pro Ala Glu Phe Ile Arg Phe His 
3505                3510                3515                3520


Pro Gln Tyr Gln Glu Val Asn Gly Thr Leu Pro Leu Ile Lys Phe Asn 
                3525                3530                3535


Gly Ala Gln Val Asn Pro Lys Phe Lys Gln Cys Asp Val Leu Gln Leu 
            3540                3545                3550


Leu Trp Thr Ser Cys Pro Ile Leu Pro Glu Lys Ala Thr Pro Leu Ser 
        3555                3560                3565


Ile Lys Glu Gln Glu Gly Ser Asp Leu Gly Pro Gln Glu Gln Leu Glu 
    3570                3575                3580


Gln Val Leu Asn Met Leu Asn Val Asn Leu Asp Pro Pro Leu Asp Lys 
3585                3590                3595                3600


Val Ile Asn Asn Cys Arg Asn Ile Cys Asn Ile Thr Thr Leu Asp Glu 
                3605                3610                3615


Glu Met Val Lys Thr Arg Ala Lys Val Leu Arg Ser Ile Tyr Glu Phe 
            3620                3625                3630


Leu Ser Ala Glu Lys Arg Glu Phe Arg Phe Gln Leu Arg Gly Val Ala 
        3635                3640                3645


Phe Val Met Val Glu Asp Gly Trp Lys Leu Leu Lys Pro Glu Glu Val 
    3650                3655                3660


Val Ile Asn Leu Glu Tyr Glu Ser Asp Phe Lys Pro Tyr Leu Tyr Lys 
3665                3670                3675                3680


Leu Pro Leu Glu Leu Gly Thr Phe His Gln Leu Phe Lys His Leu Gly 
                3685                3690                3695


Thr Glu Asp Ile Ile Ser Thr Lys Gln Tyr Val Glu Val Leu Ser Arg 
            3700                3705                3710


Ile Phe Lys Asn Ser Glu Gly Lys Gln Leu Asp Pro Asn Glu Met Arg 
        3715                3720                3725


Thr Val Lys Arg Val Val Ser Gly Leu Phe Arg Ser Leu Gln Asn Asp 
    3730                3735                3740


Ser Val Lys Val Arg Ser Asp Leu Glu Asn Val Arg Asp Leu Ala Leu 
3745                3750                3755                3760


Tyr Leu Pro Ser Gln Asp Gly Arg Leu Val Lys Ser Ser Ile Leu Val 
                3765                3770                3775


Phe Asp Asp Ala Pro His Tyr Lys Ser Arg Ile Gln Gly Asn Ile Gly 
            3780                3785                3790


Val Gln Met Leu Val Asp Leu Ser Gln Cys Tyr Leu Gly Lys Asp His 
        3795                3800                3805


Gly Phe His Thr Lys Leu Ile Met Leu Phe Pro Gln Lys Leu Arg Pro 
    3810                3815                3820


Arg Leu Leu Ser Ser Ile Leu Glu Glu Gln Leu Asp Glu Glu Thr Pro 
3825                3830                3835                3840


Lys Val Cys Gln Phe Gly Ala Leu Cys Ser Leu Gln Gly Arg Leu Gln 
                3845                3850                3855


Leu Leu Leu Ser Ser Glu Gln Phe Ile Thr Gly Leu Ile Arg Ile Met 
            3860                3865                3870


Lys His Glu Asn Asp Asn Ala Phe Leu Ala Asn Glu Glu Lys Ala Ile 
        3875                3880                3885


Arg Leu Cys Lys Ala Leu Arg Glu Gly Leu Lys Val Ser Cys Phe Glu 
    3890                3895                3900


Lys Leu Gln Thr Thr Leu Arg Val Lys Gly Phe Asn Pro Ile Pro His 
3905                3910                3915                3920


Ser Arg Ser Glu Thr Phe Ala Phe Leu Lys Arg Phe Gly Asn Ala Val 
                3925                3930                3935


Ile Leu Leu Tyr Ile Gln His Ser Asp Ser Lys Asp Ile Asn Phe Leu 
            3940                3945                3950


Leu Ala Leu Ala Met Thr Leu Lys Ser Ala Thr Asp Asn Leu Ile Ser 
        3955                3960                3965


Asp Thr Ser Tyr Leu Ile Ala Met Leu Gly Cys Asn Asp Ile Tyr Arg 
    3970                3975                3980


Ile Gly Glu Lys Leu Asp Ser Leu Gly Val Lys Tyr Asp Ser Ser Glu 
3985                3990                3995                4000


Pro Ser Lys Leu Glu Leu Pro Met Pro Gly Thr Pro Ile Pro Ala Glu 
                4005                4010                4015


Ile His Tyr Thr Leu Leu Met Asp Pro Met Asn Val Phe Tyr Pro Gly 
            4020                4025                4030


Glu Tyr Val Gly Tyr Leu Val Asp Ala Glu Gly Gly Asp Ile Tyr Gly 
        4035                4040                4045


Ser Tyr Gln Pro Thr Tyr Thr Tyr Ala Ile Ile Val Gln Glu Val Glu 
    4050                4055                4060


Arg Glu Asp Ala Asp Asn Ser Ser Phe Leu Gly Lys Ile Tyr Gln Ile 
4065                4070                4075                4080


Asp Ile Gly Tyr Ser Glu Tyr Lys Ile Val Ser Ser Leu Asp Leu Tyr 
                4085                4090                4095


Lys Phe Ser Arg Pro Glu Glu Ser Ser Gln Ser Arg Asp Ser Ala Pro 
            4100                4105                4110


Ser Thr Pro Thr Ser Pro Thr Glu Phe Leu Thr Pro Gly Leu Arg Ser 
        4115                4120                4125


Ile Pro Pro Leu Phe Ser Gly Arg Glu Ser His Lys Thr Ser Ser Lys 
    4130                4135                4140


His Gln Ser Pro Lys Lys Leu Lys Val Asn Ser Leu Pro Glu Ile Leu 
4145                4150                4155                4160


Lys Glu Val Thr Ser Val Val Glu Gln Ala Trp Lys Leu Pro Glu Ser 
                4165                4170                4175


Glu Arg Lys Lys Ile Ile Arg Arg Leu Tyr Leu Lys Trp His Pro Asp 
            4180                4185                4190


Lys Asn Pro Glu Asn His Asp Ile Ala Asn Glu Val Phe Lys His Leu 
        4195                4200                4205


Gln Asn Glu Ile Asn Arg Leu Glu Lys Gln Ala Phe Leu Asp Gln Asn 
    4210                4215                4220


Ala Asp Arg Ala Ser Arg Arg Thr Phe Ser Thr Ser Ala Ser Arg Phe 
4225                4230                4235                4240


Gln Ser Asp Lys Tyr Ser Phe Gln Arg Phe Tyr Thr Ser Trp Asn Gln 
                4245                4250                4255


Glu Ala Thr Ser His Lys Ser Glu Arg Gln Gln Gln Asn Lys Glu Lys 
            4260                4265                4270


Cys Pro Pro Ser Ala Gly Gln Thr Tyr Ser Gln Arg Phe Phe Val Pro 
        4275                4280                4285


Pro Thr Phe Lys Ser Val Gly Asn Pro Val Glu Ala Arg Arg Trp Leu 
    4290                4295                4300


Arg Gln Ala Arg Ala Asn Phe Ser Ala Ala Arg Asn Asp Leu His Lys 
4305                4310                4315                4320


Asn Ala Asn Glu Trp Val Cys Phe Lys Cys Tyr Leu Ser Thr Lys Leu 
                4325                4330                4335


Ala Leu Ile Ala Ala Asp Tyr Ala Val Arg Gly Lys Ser Asp Lys Asp 
            4340                4345                4350


Val Lys Pro Thr Ala Leu Ala Gln Lys Ile Glu Glu Tyr Ser Gln Gln 
        4355                4360                4365


Leu Glu Gly Leu Thr Asn Asp Val His Thr Leu Glu Ala Tyr Gly Val 
    4370                4375                4380


Asp Ser Leu Lys Thr Arg Tyr Pro Asp Leu Leu Pro Phe Pro Gln Ile 
4385                4390                4395                4400


Pro Asn Asp Arg Phe Thr Ser Glu Val Ala Met Arg Val Met Glu Cys 
                4405                4410                4415


Thr Ala Cys Ile Ile Ile Lys Leu Glu Asn Phe Met Gln Gln Lys Val 
            4420                4425                4430


<210>  8234
<211>  15137
<212>  DNA
<213>  Homo sapiens

<400>  8234
ctgctcctcg gccgccgcgg cttcctctag cgtttcctcc tcggcgcggg ctgctgcgta     60

cgggactgcg ccatgcggat cccgccctcc cggcccgcgc ggggcctgtg gacgcggtag    120

ggccggccgt gatcgggcgc cggcgtcagg ggcgggcgct aggggcgcct gccgcgccgc    180

gatgtgggag aggtgggtcc cggtgaccgt gctccccggc tgcgtgggct gcaggaccgt    240

cgcggcgctg gcgtcctgga ccgtgcgcga tgtgaaggaa cgtatcttcg cggagactgg    300

cttcccggtg tcggagcagc ggctgtggcg cggcggccgc gaggtcgatt tggtcagaca    360

acgccaccac ttgttgattt tctcaaggac attttgagaa gatatccaga aggaggacag    420

attcttaagg aattaattca gaatgcagaa gatgctgggg cgacagaagt taaattttta    480

tatgatgaaa ctcaatacgg aacagagact ctttggtcaa aagatatggc gccatatcag    540

gggccagctc tctatgtgta caacaacgcg gttttcaccc cagaggactg gcacggcatt    600

caagaaatag caagaagcag gaaaaaggat gatcctctga aggtcggaag atttggaatt    660

gggtttaatt ctgtctatca tataacagat gttccttgta tctttagtgg tgaccaaatc    720

gggatgctag atcctcatca aacacttttt ggcccacatg aatcaggcca atgttggaat    780

ctcaaagatg acagcaaaga aattagtgaa ctttcagacc agtttgcacc atttgttggc    840

atttttggaa gcaccaagga aacatttata aacggcaatt ttccaggaac atttttccgt    900

ttccctcttc gcctacaacc ttcacaactt agtagtaacc tctacaataa gcagaaggtt    960

cttgagttgt ttgagtcttt tagggcagat gcagacacag tgctgctctt tctgaaaagt   1020

gtgcaggatg tttccttata tgtccgagag gctgacggaa cagagaaact ggtgtttaga   1080

gtgacttcga gtgagagtaa ggcactgaaa catgagcggc cgaattctat aaagattctg   1140

ggaactgcta taagtaacta ttgtaaaaag actccaagca ataacatcac ctgtgtaaca   1200

tatcacgtaa atattgtttt agaagaggag agtactaagg atgcacagaa aacatcttgg   1260

ttggtgtgta acagtgtggg tgggcgaggg atcagtagta agcttgactc tttagctgat   1320

gaactgaaat ttgtcccaat cattggaata gccatgcctt tatcaagcag agatgatgaa   1380

gcaaaaggag caacgtctga tttctcagga aaagcatttt gtttccttcc tttaccacct   1440

ggtgaggaaa gcagcacagg cctcccagtt cacatcagtg ggttctttgg ccttactgat   1500

aaccgcagga gcataaaatg gagagagctg gaccagtgga gagacccggc agccttatgg   1560

aatgagtttc ttgtcatgaa tgttgtcccc aaagcttatg ctactctgat cttagattca   1620

ataaaacgtc tggagatgga aaagagctct gatttcccct tgtcagttga tgttatctat   1680

aagctttggc cggaggcgag caaagtcaag gtgcactggc aaccggtgtt agagcctcta   1740

ttcagcgagc tgttgcagaa tgcagtgatt tattcaatta gctgtgactg ggtcaggttg   1800

gagcaggtgt acttctcaga acttgatgaa aatttagaat acacaaaaac tgtgctcaac   1860

tacctccaga gctcagggaa gcagattgcc aaggtaccag ggaatgtgga tgctgctgtt   1920

cagctcacag ctgcctctgg cacaacacct gtgaggaagg tgacgcccgc gtgggtgcgg   1980

caggtgctgc ggaagtgtgc acacctgggc tgtgctgaag aaaagcttca ccttctagaa   2040

tttgtgcttt ctgaccaagc ctacagtgag ctgcttgggc tggagctgct ccctttacaa   2100

aatggcaatt ttgtcccctt ctcctcatct gtatcagacc aagatgtcat ttatattacc   2160

tcagcagaat atccaaggtc ccttttccca agtcttgaag gaagatttat tttggataac   2220

ttgaaacctc accttgtggc tgctttaaag gaagctgccc aaacccgagg aagaccatgt   2280

actcagctgc agcttctaaa tccagaacga tttgcacgtc ttatcaagga agtaatgaat   2340

acattctggc ctggcagaga attgattgtt caatggtatc catttgatga aaacagaaat   2400

cacccatctg tttcatggct taagatggtt tggaaaaatc tttatataca tttttcagag   2460

gatttgactt tatttgatga gatgccactt atccccagaa ctatactaga ggaaggtcag   2520

acatgtgtgg aactcattag actcaggatt ccatcgttag tcattttaga cgatgaatct   2580

gaagcacagc ttccagaatt tttagcagac attgtacaaa aacttggagg gtttgtcctt   2640

aaaaaattag atgcatctat acaacatccg cttattaaaa aatatattca ttcaccatta   2700

ccaagtgctg ttttgcagat aatggagaag atgccattgc agaaattgtg taatcaaata   2760

acttcgctac ttccaacaca caaagatgcc ctgaggaagt tcttggctag tttaaccgat   2820

agcagtgaga aagagaaaag aattattcaa gaattggcaa tattcaagcg cattaaccat   2880

tcttctgatc agggaatttc ctcttataca aaattgaaag gttgtaaagt cttacaccat   2940

actgccaaac tcccagcaga tctgcgactt tctatttcag taatagacag tagtgatgaa   3000

gctactattc gtctggcaaa catgttgaaa atagaacagt taaagaccac tagctgctta   3060

aagcttgttt taaaagatat tgaaaatgca ttttattcac atgaagaggt aacacagctt   3120

atgttatggg tccttgagaa tctatcttct cttaaaaatg agaatccaaa tgtgcttgag   3180

tggttaacac cattaaaatt catccagata tcacaggaac agatggtatc agctggtgaa   3240

ctctttgacc ctgatataga agtactaaag gatctctttt gtaatgaaga aggaacctat   3300

ttcccaccct cagtttttac ctcaccagat attcttcact ccttaagaca gattggttta   3360

aaaaacgaag ccagtctcaa agaaaaggat gttgtgcaag tggcaaaaaa aattgaagcc   3420

ttacaggtcg gtgcttgtcc tgatcaagat gttcttctga agaaagccaa aaccctctta   3480

ctggttttaa ataagaatca cacactgttg caatcatctg aaggaaagat gacattgaag   3540

aaaataaaat gggttccagc ctgcaaggaa aggcctccaa attatccagg ctctttggtc   3600

tggaaaggag atctctgtaa tctctgtgca ccaccagata tgtgtgatgt aggccatgca   3660

attctcattg gctcctcact tcctcttgtt gaaagtatcc atgtaaacct ggaaaaagca   3720

ttagggatct tcacaaaacc tagccttagt gctgtcttaa aacactttaa aattgttgtt   3780

gattggtatt cttcaaaaac ctttagtgat gaagactact atcaattcca gcatattttg   3840

cttgagattt acggattcat gcatgatcat ctaaatgaag ggaaagattc ttttagagcc   3900

ttaaaatttc catgggtttg gactggcaaa aagttttgtc cacttgccca ggctgtgatt   3960

aaaccaatcc atgatcttga ccttcagcct tatttgcata atgtacctaa aaccatggca   4020

aaattccacc aactatttaa ggtctgtggt tcaatagagg agttgacatc agatcatatt   4080

tccatggtta ttcagaagat atatctcaaa agtgaccaag atctcagtga acaagaaagc   4140

aaacaaaatc ttcatcttat gttgaatatt atcagatggc tgtatagcaa tcagattcca   4200

gcaagcccca acacaccagt tcctatacat catagcaaaa atccttctaa acttatcatg   4260

aagccaattc acgaatgctg ttattgtgac attaaagttg atgaccttaa tgacttactt   4320

gaagattctg tggaaccaat cattttggtg catgaggaca tacccatgaa aactgcagaa   4380

tggctaaaag ttccatgcct tagtacaaga ctgataaatc ctgaaaacat gggatttgag   4440

cagtcaggac aaagagagcc acttactgta agaattaaaa atattctgga agaataccct   4500

tcagtgtcag atatttttaa agaactactt caaaacgctg atgatgcaaa tgcaacagaa   4560

tgcagtttct tgattgatat gagaagaaat atggacataa gagagaatct cctagaccca   4620

gggatggcag cttgtcatgg acctgctttg tggtcattca acaattctca attctcagat   4680

tcagattttg tgaacataac taggttagga gaatctttaa aaaggggaga agttgacaaa   4740

gttggaaaat ttggtcttgg atttaattct gtgtaccata tcactgacat tcccatcatt   4800

atgagtcggg aattcatgat aatgttcgat ccaaacataa atcatatcag taaacacatt   4860

aaagacaaat ccaatcctgg gatcaaaatt aattggagta aacaacagaa aagacttaga   4920

aaatttccta atcagttcaa accatttata gatgtatttg gctgtcagtt acctttgact   4980

gtagaagcac cttacagcta taatggaacc cttttccgac tgtcctttag aactcaacag   5040

gaagcaaaag tgagtgaagt tagtagtacg tgctacaata cagcagatat ttattctctt   5100

gtggatgaat ttagtctctg tggacacagg cttatcattt tcactcagag tgtaaagtca   5160

atgtatttga agtacttgaa aattgaggaa accaacccca gtttagcaca agatacagta   5220

ataattaaaa aaaaatcctg ctcttccaaa gcattgaaca cacctgtctt aagtgtttta   5280

aaagaggctg ctaagctcat gaagacttgc agcagcagta ataaaaagct tcccagtgat   5340

gaaccaaagt catcttgcat tcttcagatc acagtggaag aatttcacca tgtgttcaga   5400

aggattgctg atttacagtc gccacttttt agaggtccag atgatgaccc agctgctctc   5460

tttgaaatgg ctaagtctgg ccaatcaaaa aagccatcag atgagttgtc acagaaaaca   5520

gtagagtgta ccacgtggct tctgtgtact tgcatggaca caggagaggc tctgaagttt   5580

tccctgagtg agagtggaag aagactagga ctggttccat gtggggcagt aggagttcag   5640

ctgtcagaaa tccaggacca gaagtggaca gtgaaaccac acattggaga ggtgttttgc   5700

tatttacctt tacgaataaa aacaggcttg ccagttcata tcaatgggtg ctttgctgtt   5760

acatcaaata ggaaagaaat ctggaaaaca gatacaaaag gacgatggaa taccacgttc   5820

atgagacatg ttattgtgaa agcttactta caggtactga gtgtcttacg ggacctggcc   5880

actagtgggg agctaatgga ttatacttac tatgcagtat ggcccgatcc tgatttagtt   5940

catgatgatt tttctgtaat ttgccaagga ttttatgaag atatagctca tggaaaaggg   6000

aaagaactga ccaaagtctt ctctgatgga tctacttggg tttccatgaa gaacgtaaga   6060

tttctagatg actctatact taaaagaaga gatgttggtt cagcagcctt caagatattt   6120

ttgaaatacc tcaagaagac tgggtccaaa aacctttgtg ctgttgaact tccttcttcg   6180

gtaaaattag gatttgaaga agctggctgc aaacagatac tacttgaaaa cacattttca   6240

gagaaacagt ttttttctga agtgtttttt ccaaatattc aagaaattga agcagaactt   6300

agagatcctt taatgatctt tgttctaaat gaaaaagttg atgagttctc gggagttctt   6360

cgtgttactc catgtattcc ttgttccttg gaggggcatc ctttggtttt gccatcaaga   6420

ttgatccacc ccgaaggacg agttgcaaag ttatttgata ttaaagatgg gagattccct   6480

tatggttcta ctcaggatta tctcaatcct attattttga ttaaactagt tcagttaggt   6540

atggcaaaag atgatatttt atgggatgat atgctagaac gtgcagtgtc agtagctgaa   6600

attaataaaa gtgatcatgt tgctgcatgc ctaagaagta gtatcttatt gagtcttatc   6660

gatgagaaac taaaaataag ggatcctaga gcaaaggatt ttgctgcaaa atatcaaaca   6720

atccgcttcc ttccatttct gacaaaacca gcaggttttt ctttggactg gaaaggcaac   6780

agttttaagc ctgaaaccat gtttgcagca actgaccttt atacagctga acatcaagat   6840

atagtttgtc ttttgcaacc aattctaaat gaaaattccc attcttttag aggttgtggt   6900

tcagtgtcat tggctgttaa agagtttttg ggattactca agaagccaac agttgatctg   6960

gttataaacc aattgaaaga agtagcaaaa tcagttgatg atggaattac actgtaccag   7020

gagaatatca ccaatgcttg ctacaaatac cttcatgaag ccttgatgca aaatgaaatc   7080

actaagatgt caattattga taagttaaaa ccctttagct tcattctagt tgagaatgca   7140

tatgttgact cagaaaaggt ttcttttcat ttaaattttg aggcggcacc atacctttat   7200

cagttgccta ataagtataa aaataatttc cgcgaacttt ttgaaaccgt gggtgtgagg   7260

cagtcatgca ctgttgaaga ttttgctctt gttttggaat ctattgatca agaaagagga   7320

acaaagcaaa taacagaaga gaattttcag ctttgccgac gaataatcag tgaaggaata   7380

tggagtctca ttagagaaaa gaaacaagaa ttttgtgaga aaaattatgg caagatatta   7440

ttgccagata ctaatcttat gcttctccct gctaaatcgt tatgctacaa tgattgccct   7500

tggataaaag taaaggatac cactgtaaaa tattgtcatg ctgacatacc cagggaagta   7560

gcagtaaaac taggagcagt cccaaagcga cacaaagcct tagaaagata tgcatccaat   7620

gtctgtttta caacacttgg cacagaattt gggcagaaag aaaaattgac cagcagaatt   7680

aagagcatcc ttaatgcata tccttctgaa aaggaaatgt tgaaagagct tcttcaaaat   7740

gctgatgatg caaaggcgac agaaatctgt tttgtgtttg atcctagaca gcatccagtt   7800

gatagaatat ttgatgataa gtgggcccca ttgcaagggc cagcactttg tgtgtacaac   7860

aaccagccat ttacagaaga tgatgttaga ggaattcaga atcttggaaa aggcacgaaa   7920

gagggaaatc cttataaaac tggacagtat ggaataggat tcaattctgt gtatcatatc   7980

acagactgcc catcttttat ttctggcaat gacatcctgt gtatttttga tcctcatgcc   8040

agatatgcac caggggccac atccattagt cccggacgca tgtttagaga tttggatgca   8100

gattttagga cacagttctc agatgttctg gatctttatc tgggaaccca ttttaaactg   8160

gataattgca caatgttcag atttcctctt cgtaatgcag aaatggcaaa agtttcggaa   8220

atttcgtctg ttccagcatc agacagaatg gtccagaatc ttttggacaa actgcgctca   8280

gatggggcag aacttctaat gtttcttaat cacatggaaa aaatttctat ttgtgaaata   8340

gataagagta ctggagctct aaatgtgctg tattcagtaa agggcaaaat cacagatgga   8400

gacagattga aaaggaaaca atttcatgca tctgtaattg atagtgttac taaaaagagg   8460

cagctcaaag acataccagt tcaacaaata acctatacta tggatactga ggactctgaa   8520

ggaaatctta ctacgtggct aatttgtaat agatcaggct tttcaagtat ggagaaagta   8580

tctaaaagtg tcatatcagc tcacaagaac caagatatta ctcttttccc acgtggtgga   8640

gtagctgcct gcattactca caactataaa aaaccccata gggccttctg ttttttgcct   8700

ctttctttgg agactgggct gccatttcat gtgaatggcc actttgcact ggattcagcc   8760

agaaggaacc tgtggcgtga tgataatgga gttggtgttc gaagtgactg gaataacagt   8820

ttaatgacag cattaatagc tcctgcatat gttgaattgc taatacagtt aaaaaaacgg   8880

tatttccctg gttctgatcc aacattatca gtgttacaga acacccctat tcatgttgta   8940

aaggacactt taaagaagtt tttatcgttt ttcccagtta accgtcttga tctacagcca   9000

gatttatatt gtctagtgaa agcactttac aattgcattc acgaagacat gaaacgtctt   9060

ttacctgttg tgcgggctcc aaatattgat ggctctgact tgcactctgc agttataatt   9120

acttggatca atatgtctac ttctaataaa actagaccat tttttgacaa tttactacag   9180

gatgaattac aacaccttaa aaatgcagat tataatatca ccacacgcaa aacagtagca   9240

gagaatgtct ataggctgaa acatctcctt ttagaaattg gtttcaactt ggtttataac   9300

tgtgatgaaa ctgctaatct ttaccactgt cttatagatg cagatattcc tgttagttat   9360

gtgacccctg ctgatatcag atctttttta atgacatttt cctctcctga cactaattgc   9420

catattggga agctgccttg tcgtctgcag cagactaatc taaaactttt tcatagttta   9480

aaacttttag ttgattattg ttttaaagat gcagaagaaa atgagattga agttgaggga   9540

ttgccccttc tcatcacact ggacagtgtt ttgcaaactt ttgatgcaaa acgacccaag   9600

tttctaacaa catatcatga attgattcca tcccgcaaag acttgtttat gaatacatta   9660

tatttgaaat atagtaatat tttattgaac tgtaaagttg caaaagtgtt tgacatttcc   9720

agctttgctg atttgttatc ctctgtgttg cctcgagaat ataagaccaa aagttgcaca   9780

aagtggaaag acaattttgc aagtgagtct tggcttaaga atgcatggca ttttattagt   9840

gaatctgtaa gtgtgaaaga agatcaggaa gaaacaaaac caacatttga cattgttgtt   9900

gatactctaa aagactgggc attgcttcca ggaacaaagt ttactgtttc agccaaccag   9960

cttgtggttc ctgaaggaga tgttctgctt cctctcagcc ttatgcacat tgcagttttt  10020

ccaaatgccc agagtgataa agtttttcat gctctaatga aagctggctg tattcagctt  10080

gctttgaaca aaatctgttc caaagacagt gcatttgttc ctttgttgtc atgtcacaca  10140

gcaaatatag agagccccac aagcatcttg aaggctctac attatatggt ccaaacttca  10200

acatttagag cagaaaaatt agtagaaaat gattttgagg cacttttgat gtatttcaac  10260

tgcaatttga atcatttgat gtcccaagat gatataaaaa ttctaaagtc acttccgtgc  10320

tataaatcca tcagtggccg ctatgtaagc attggaaaat ttggaacatg ctacgtactt  10380

acaaaaagta tcccttcagc tgaagtggag aaatggacac agtcatcatc atctgcattt  10440

cttgaagaaa aaatacactt aaaagaacta tatgaggtga ttggttgtgt acctgtagat  10500

gatcttgagg tatatttgaa acacctctta ccaaaaattg aaaatctctc ttatgatgca  10560

aaattagagc acttgatcta ccttaagaat agattatcaa gtgctgagga attatcagag  10620

attaaggaac aactttttga aaaactggaa agtttattga taatccatga tgctaacagt  10680

agactaaagc aagcaaagca tttctatgat agaactgtga gagtttttga agttatgctt  10740

cctgaaaaat tgtttattcc taatgatttc tttaagaaat tggaacaact tataaaaccc  10800

aaaaatcatg ttacatttat gacatcctgg gtggaattct taagaaatat tggactaaaa  10860

tacatacttt ctcagcagca gttgttacag tttgctaagg aaatcagtgt gagggctaat  10920

acagaaaact ggtccaaaga aacattgcaa aatacagttg atatccttct gcatcatata  10980

ttccaagaac gaatggattt gttatctgga aattttctga aagaactatc tttaatacca  11040

ttcttatgtc ctgagcgggc ccccgcggaa ttcattagat ttcatcctca atatcaagag  11100

gtaaatggaa cacttcctct tataaagttc aatggagcac aggtaaatcc aaaattcaag  11160

caatgtgatg tactccagct gttatggaca tcctgcccta ttcttccaga gaaagctaca  11220

cccttaagca ttaaagaaca agaaggtagt gaccttggtc cacaagaaca gcttgaacaa  11280

gttttaaata tgcttaatgt taacctggat cctcctcttg ataaggtaat caataactgc  11340

agaaacatat gcaacataac gacgttggat gaagaaatgg taaaaactag agcaaaagtc  11400

ttaaggagca tatatgaatt cctcagtgca gaaaaaaggg aatttcgttt tcagttgcga  11460

ggggttgctt ttgtgatggt agaagatggt tggaaacttc tgaagcctga ggaggtagtc  11520

ataaacctag aatatgaatc tgattttaaa ccttatttgt acaagctacc tttagaactt  11580

ggcacatttc accagttgtt caaacactta ggtactgaag atattatttc aactaagcaa  11640

tatgttgaag tgttgagccg catatttaaa aattctgagg gcaaacaatt agatcctaat  11700

gaaatgcgta cagttaagag agtagtttct ggtctgttca ggagtctaca gaatgattca  11760

gtcaaggtga ggagtgatct cgagaatgta cgagaccttg cgctttacct cccaagccag  11820

gatggtagat tggtaaagtc aagcatctta gtgtttgacg atgcgccaca ttataaaagt  11880

agaatccagg ggaatattgg tgtgcaaatg ttagttgatc tcagccagtg ctacttaggg  11940

aaagaccatg gatttcacac taagttgata atgctctttc ctcaaaaact tagacctcga  12000

ttattgagca gtatacttga agaacaatta gatgaagaga ctcccaaagt ttgtcagttt  12060

ggagcgttgt gttctcttca aggaagattg cagttactct tgtcttctga acagttcatt  12120

acaggactga ttagaattat gaagcatgaa aatgataatg cttttctggc caatgaagaa  12180

aaagccataa gactttgcaa agccctaaga gaaggattga aagtatcctg ctttgaaaag  12240

cttcaaacaa cattaagagt taaaggtttt aatcctattc cccacagcag aagtgaaact  12300

tttgcttttt tgaagcgatt tggtaatgca gtcatcttgc tctacattca acattcagac  12360

agtaaagaca ttaatttcct gttagcattg gcaatgactc ttaaatcagc aactgacaat  12420

ttgatttctg acacttcata tttaattgct atgctaggat gcaatgatat ttacaggatt  12480

ggtgagaaac ttgacagttt aggagtgaaa tatgactctt cggagccatc aaaactggaa  12540

cttccaatgc ctggcacacc aattcctgct gaaattcatt acactctgct tatggaccca  12600

atgaatgttt tttacccggg agaatatgtt gggtaccttg ttgatgctga aggtggtgat  12660

atctatggat cataccagcc aacatacaca tatgcaatta ttgtacaaga agttgaaaga  12720

gaagatgctg acaattctag ttttctagga aagatatatc agatagatat tggttatagt  12780

gaatataaaa tagttagctc tcttgatctg tataagtttt caagacctga ggaaagctct  12840

caaagcaggg acagtgctcc ttctacacca accagcccca ctgagttcct cacccctggc  12900

ctgagaagca ttcctcctct tttctctggt agagagagcc acaagacttc ttccaaacat  12960

cagtccccca aaaagcttaa ggttaattct ttaccagaaa tcttaaaaga agtgacatct  13020

gtggtggagc aagcatggaa gcttccagaa tcggaacgaa aaaagattat taggcggttg  13080

tatttgaaat ggcatcctga caaaaatcca gagaaccatg acattgccaa tgaagttttt  13140

aaacatttgc agaatgaaat caacagatta gaaaaacagg cttttctaga tcaaaatgca  13200

gacagggcct ccagacgaac attttcaacc tcagcatccc gatttcagtc agacaaatac  13260

tcatttcaga gattctatac ttcatggaat caagaagcaa cgagccataa atctgaaaga  13320

cagcaacaga acaaagaaaa atgcccccct tcagccggac agacttactc tcaaaggttc  13380

tttgttcctc ccactttcaa gtcggttggc aatccagtgg aagcacgcag atggctaaga  13440

caagccagag caaacttctc agctgccagg aatgaccttc ataaaaatgc caatgagtgg  13500

gtgtgcttta aatgttacct ttctaccaag ttagctttga ttgcagctga ctatgctgtg  13560

aggggaaagt ctgataaaga tgtaaaacca actgcacttg ctcagaaaat agaggaatat  13620

agtcagcaac ttgaaggact gacaaatgat gttcacacat tggaagctta tggtgtagac  13680

agtttaaaaa caagataccc tgatttgctt ccctttcctc agatcccaaa tgacaggttc  13740

acttctgagg ttgctatgag ggtgatggaa tgtactgcct gtatcataat aaaacttgaa  13800

aattttatgc aacaaaaagt gtgaagatat ttaacgaaaa aaaaggtaga tcttgaatgt  13860

gttgtagcac gaataaattg ctgtacttca ttaagcttca ttgccaatta gctaggaatt  13920

gttaagcaca ttgcagattg ttcttggaga attctggagt tgttatgaac atgaatacca  13980

acggaaaacc ttaactgaat ctaaaagaaa actattttga agatggtggt gagctgcaaa  14040

atagctggat ggatttgaat gattgggatg atacatcatt gaactgcact ttatataacc  14100

aaagcttagc agtttgttag ataagagtct atgtatgtct ctggttagga tgaagttaat  14160

tttatgtttt taacatggta tttttgaagg agctaatgaa acactggaca tataattggt  14220

ttaaacataa ggggaattaa gtctttgtag tctgtcattt ttttaagtgg atcctcttgg  14280

atgcgttatt ttctcatcag ctggctctga tcatgaattt gttgtaattt tatgttgtac  14340

tcagtgcatt taagaaatgg tagagtattt taatcctatt acttgactaa gagtgtgaag  14400

gtagtacttt ttagagtgca ctgagtgcac tttacatctt tatttaaatt tttttttaac  14460

atcttatgtt tacaggcttc ctgtttgatg aagatagcaa cggaaaactc aaaatggtgg  14520

cagttcttat taccagttgt tagtattgtt tctggaaact gcttgccaag acaacattta  14580

ttaactgtta gaacacttgc tttatgtttg tgtgtacata ttttccacaa atgttataat  14640

ttatatagtg tggttgaaca ggatgcaatc ttttgttgtc taaaggtgct gcagttaaaa  14700

aaaaaacaac cttttctttc aatatggcat gtagtggagt ttttttaact ttaaaaacat  14760

caaaaattgt taaaatcatt gtgttatcta gtagtttata attatcggct tatatttccc  14820

catgaatgat cagaactgac atttaattca tgtttgtctc gccatgcttc tttactttaa  14880

catatttctt ttgcagaatg taaaaggtaa tgataattag tttatataag tgtactggct  14940

gtaaatgatg ctaaatatac tttatgcaat taagggctta cagaacatgt tgaaactttt  15000

tttactttta ttgggaataa ggaatgtttg cacctccaca ttttattgct tctggatgtg  15060

aaatcatgta attatttctg ctgttatata aagtgccata cttttaataa aggaaaatgt  15120

acatatgaaa tcatcgt                                                 15137


<210>  8235
<211>  4432
<212>  PRT
<213>  Homo sapiens

<400>  8235

Met Ala Pro Tyr Gln Gly Pro Ala Leu Tyr Val Tyr Asn Asn Ala Val 
1               5                   10                  15


Phe Thr Pro Glu Asp Trp His Gly Ile Gln Glu Ile Ala Arg Ser Arg 
            20                  25                  30


Lys Lys Asp Asp Pro Leu Lys Val Gly Arg Phe Gly Ile Gly Phe Asn 
        35                  40                  45


Ser Val Tyr His Ile Thr Asp Val Pro Cys Ile Phe Ser Gly Asp Gln 
    50                  55                  60


Ile Gly Met Leu Asp Pro His Gln Thr Leu Phe Gly Pro His Glu Ser 
65                  70                  75                  80


Gly Gln Cys Trp Asn Leu Lys Asp Asp Ser Lys Glu Ile Ser Glu Leu 
                85                  90                  95


Ser Asp Gln Phe Ala Pro Phe Val Gly Ile Phe Gly Ser Thr Lys Glu 
            100                 105                 110


Thr Phe Ile Asn Gly Asn Phe Pro Gly Thr Phe Phe Arg Phe Pro Leu 
        115                 120                 125


Arg Leu Gln Pro Ser Gln Leu Ser Ser Asn Leu Tyr Asn Lys Gln Lys 
    130                 135                 140


Val Leu Glu Leu Phe Glu Ser Phe Arg Ala Asp Ala Asp Thr Val Leu 
145                 150                 155                 160


Leu Phe Leu Lys Ser Val Gln Asp Val Ser Leu Tyr Val Arg Glu Ala 
                165                 170                 175


Asp Gly Thr Glu Lys Leu Val Phe Arg Val Thr Ser Ser Glu Ser Lys 
            180                 185                 190


Ala Leu Lys His Glu Arg Pro Asn Ser Ile Lys Ile Leu Gly Thr Ala 
        195                 200                 205


Ile Ser Asn Tyr Cys Lys Lys Thr Pro Ser Asn Asn Ile Thr Cys Val 
    210                 215                 220


Thr Tyr His Val Asn Ile Val Leu Glu Glu Glu Ser Thr Lys Asp Ala 
225                 230                 235                 240


Gln Lys Thr Ser Trp Leu Val Cys Asn Ser Val Gly Gly Arg Gly Ile 
                245                 250                 255


Ser Ser Lys Leu Asp Ser Leu Ala Asp Glu Leu Lys Phe Val Pro Ile 
            260                 265                 270


Ile Gly Ile Ala Met Pro Leu Ser Ser Arg Asp Asp Glu Ala Lys Gly 
        275                 280                 285


Ala Thr Ser Asp Phe Ser Gly Lys Ala Phe Cys Phe Leu Pro Leu Pro 
    290                 295                 300


Pro Gly Glu Glu Ser Ser Thr Gly Leu Pro Val His Ile Ser Gly Phe 
305                 310                 315                 320


Phe Gly Leu Thr Asp Asn Arg Arg Ser Ile Lys Trp Arg Glu Leu Asp 
                325                 330                 335


Gln Trp Arg Asp Pro Ala Ala Leu Trp Asn Glu Phe Leu Val Met Asn 
            340                 345                 350


Val Val Pro Lys Ala Tyr Ala Thr Leu Ile Leu Asp Ser Ile Lys Arg 
        355                 360                 365


Leu Glu Met Glu Lys Ser Ser Asp Phe Pro Leu Ser Val Asp Val Ile 
    370                 375                 380


Tyr Lys Leu Trp Pro Glu Ala Ser Lys Val Lys Val His Trp Gln Pro 
385                 390                 395                 400


Val Leu Glu Pro Leu Phe Ser Glu Leu Leu Gln Asn Ala Val Ile Tyr 
                405                 410                 415


Ser Ile Ser Cys Asp Trp Val Arg Leu Glu Gln Val Tyr Phe Ser Glu 
            420                 425                 430


Leu Asp Glu Asn Leu Glu Tyr Thr Lys Thr Val Leu Asn Tyr Leu Gln 
        435                 440                 445


Ser Ser Gly Lys Gln Ile Ala Lys Val Pro Gly Asn Val Asp Ala Ala 
    450                 455                 460


Val Gln Leu Thr Ala Ala Ser Gly Thr Thr Pro Val Arg Lys Val Thr 
465                 470                 475                 480


Pro Ala Trp Val Arg Gln Val Leu Arg Lys Cys Ala His Leu Gly Cys 
                485                 490                 495


Ala Glu Glu Lys Leu His Leu Leu Glu Phe Val Leu Ser Asp Gln Ala 
            500                 505                 510


Tyr Ser Glu Leu Leu Gly Leu Glu Leu Leu Pro Leu Gln Asn Gly Asn 
        515                 520                 525


Phe Val Pro Phe Ser Ser Ser Val Ser Asp Gln Asp Val Ile Tyr Ile 
    530                 535                 540


Thr Ser Ala Glu Tyr Pro Arg Ser Leu Phe Pro Ser Leu Glu Gly Arg 
545                 550                 555                 560


Phe Ile Leu Asp Asn Leu Lys Pro His Leu Val Ala Ala Leu Lys Glu 
                565                 570                 575


Ala Ala Gln Thr Arg Gly Arg Pro Cys Thr Gln Leu Gln Leu Leu Asn 
            580                 585                 590


Pro Glu Arg Phe Ala Arg Leu Ile Lys Glu Val Met Asn Thr Phe Trp 
        595                 600                 605


Pro Gly Arg Glu Leu Ile Val Gln Trp Tyr Pro Phe Asp Glu Asn Arg 
    610                 615                 620


Asn His Pro Ser Val Ser Trp Leu Lys Met Val Trp Lys Asn Leu Tyr 
625                 630                 635                 640


Ile His Phe Ser Glu Asp Leu Thr Leu Phe Asp Glu Met Pro Leu Ile 
                645                 650                 655


Pro Arg Thr Ile Leu Glu Glu Gly Gln Thr Cys Val Glu Leu Ile Arg 
            660                 665                 670


Leu Arg Ile Pro Ser Leu Val Ile Leu Asp Asp Glu Ser Glu Ala Gln 
        675                 680                 685


Leu Pro Glu Phe Leu Ala Asp Ile Val Gln Lys Leu Gly Gly Phe Val 
    690                 695                 700


Leu Lys Lys Leu Asp Ala Ser Ile Gln His Pro Leu Ile Lys Lys Tyr 
705                 710                 715                 720


Ile His Ser Pro Leu Pro Ser Ala Val Leu Gln Ile Met Glu Lys Met 
                725                 730                 735


Pro Leu Gln Lys Leu Cys Asn Gln Ile Thr Ser Leu Leu Pro Thr His 
            740                 745                 750


Lys Asp Ala Leu Arg Lys Phe Leu Ala Ser Leu Thr Asp Ser Ser Glu 
        755                 760                 765


Lys Glu Lys Arg Ile Ile Gln Glu Leu Ala Ile Phe Lys Arg Ile Asn 
    770                 775                 780


His Ser Ser Asp Gln Gly Ile Ser Ser Tyr Thr Lys Leu Lys Gly Cys 
785                 790                 795                 800


Lys Val Leu His His Thr Ala Lys Leu Pro Ala Asp Leu Arg Leu Ser 
                805                 810                 815


Ile Ser Val Ile Asp Ser Ser Asp Glu Ala Thr Ile Arg Leu Ala Asn 
            820                 825                 830


Met Leu Lys Ile Glu Gln Leu Lys Thr Thr Ser Cys Leu Lys Leu Val 
        835                 840                 845


Leu Lys Asp Ile Glu Asn Ala Phe Tyr Ser His Glu Glu Val Thr Gln 
    850                 855                 860


Leu Met Leu Trp Val Leu Glu Asn Leu Ser Ser Leu Lys Asn Glu Asn 
865                 870                 875                 880


Pro Asn Val Leu Glu Trp Leu Thr Pro Leu Lys Phe Ile Gln Ile Ser 
                885                 890                 895


Gln Glu Gln Met Val Ser Ala Gly Glu Leu Phe Asp Pro Asp Ile Glu 
            900                 905                 910


Val Leu Lys Asp Leu Phe Cys Asn Glu Glu Gly Thr Tyr Phe Pro Pro 
        915                 920                 925


Ser Val Phe Thr Ser Pro Asp Ile Leu His Ser Leu Arg Gln Ile Gly 
    930                 935                 940


Leu Lys Asn Glu Ala Ser Leu Lys Glu Lys Asp Val Val Gln Val Ala 
945                 950                 955                 960


Lys Lys Ile Glu Ala Leu Gln Val Gly Ala Cys Pro Asp Gln Asp Val 
                965                 970                 975


Leu Leu Lys Lys Ala Lys Thr Leu Leu Leu Val Leu Asn Lys Asn His 
            980                 985                 990


Thr Leu Leu Gln Ser Ser Glu Gly Lys Met Thr Leu Lys Lys Ile Lys 
        995                 1000                1005


Trp Val Pro Ala Cys Lys Glu Arg Pro Pro Asn Tyr Pro Gly Ser Leu 
    1010                1015                1020


Val Trp Lys Gly Asp Leu Cys Asn Leu Cys Ala Pro Pro Asp Met Cys 
1025                1030                1035                1040


Asp Val Gly His Ala Ile Leu Ile Gly Ser Ser Leu Pro Leu Val Glu 
                1045                1050                1055


Ser Ile His Val Asn Leu Glu Lys Ala Leu Gly Ile Phe Thr Lys Pro 
            1060                1065                1070


Ser Leu Ser Ala Val Leu Lys His Phe Lys Ile Val Val Asp Trp Tyr 
        1075                1080                1085


Ser Ser Lys Thr Phe Ser Asp Glu Asp Tyr Tyr Gln Phe Gln His Ile 
    1090                1095                1100


Leu Leu Glu Ile Tyr Gly Phe Met His Asp His Leu Asn Glu Gly Lys 
1105                1110                1115                1120


Asp Ser Phe Arg Ala Leu Lys Phe Pro Trp Val Trp Thr Gly Lys Lys 
                1125                1130                1135


Phe Cys Pro Leu Ala Gln Ala Val Ile Lys Pro Ile His Asp Leu Asp 
            1140                1145                1150


Leu Gln Pro Tyr Leu His Asn Val Pro Lys Thr Met Ala Lys Phe His 
        1155                1160                1165


Gln Leu Phe Lys Val Cys Gly Ser Ile Glu Glu Leu Thr Ser Asp His 
    1170                1175                1180


Ile Ser Met Val Ile Gln Lys Ile Tyr Leu Lys Ser Asp Gln Asp Leu 
1185                1190                1195                1200


Ser Glu Gln Glu Ser Lys Gln Asn Leu His Leu Met Leu Asn Ile Ile 
                1205                1210                1215


Arg Trp Leu Tyr Ser Asn Gln Ile Pro Ala Ser Pro Asn Thr Pro Val 
            1220                1225                1230


Pro Ile His His Ser Lys Asn Pro Ser Lys Leu Ile Met Lys Pro Ile 
        1235                1240                1245


His Glu Cys Cys Tyr Cys Asp Ile Lys Val Asp Asp Leu Asn Asp Leu 
    1250                1255                1260


Leu Glu Asp Ser Val Glu Pro Ile Ile Leu Val His Glu Asp Ile Pro 
1265                1270                1275                1280


Met Lys Thr Ala Glu Trp Leu Lys Val Pro Cys Leu Ser Thr Arg Leu 
                1285                1290                1295


Ile Asn Pro Glu Asn Met Gly Phe Glu Gln Ser Gly Gln Arg Glu Pro 
            1300                1305                1310


Leu Thr Val Arg Ile Lys Asn Ile Leu Glu Glu Tyr Pro Ser Val Ser 
        1315                1320                1325


Asp Ile Phe Lys Glu Leu Leu Gln Asn Ala Asp Asp Ala Asn Ala Thr 
    1330                1335                1340


Glu Cys Ser Phe Leu Ile Asp Met Arg Arg Asn Met Asp Ile Arg Glu 
1345                1350                1355                1360


Asn Leu Leu Asp Pro Gly Met Ala Ala Cys His Gly Pro Ala Leu Trp 
                1365                1370                1375


Ser Phe Asn Asn Ser Gln Phe Ser Asp Ser Asp Phe Val Asn Ile Thr 
            1380                1385                1390


Arg Leu Gly Glu Ser Leu Lys Arg Gly Glu Val Asp Lys Val Gly Lys 
        1395                1400                1405


Phe Gly Leu Gly Phe Asn Ser Val Tyr His Ile Thr Asp Ile Pro Ile 
    1410                1415                1420


Ile Met Ser Arg Glu Phe Met Ile Met Phe Asp Pro Asn Ile Asn His 
1425                1430                1435                1440


Ile Ser Lys His Ile Lys Asp Lys Ser Asn Pro Gly Ile Lys Ile Asn 
                1445                1450                1455


Trp Ser Lys Gln Gln Lys Arg Leu Arg Lys Phe Pro Asn Gln Phe Lys 
            1460                1465                1470


Pro Phe Ile Asp Val Phe Gly Cys Gln Leu Pro Leu Thr Val Glu Ala 
        1475                1480                1485


Pro Tyr Ser Tyr Asn Gly Thr Leu Phe Arg Leu Ser Phe Arg Thr Gln 
    1490                1495                1500


Gln Glu Ala Lys Val Ser Glu Val Ser Ser Thr Cys Tyr Asn Thr Ala 
1505                1510                1515                1520


Asp Ile Tyr Ser Leu Val Asp Glu Phe Ser Leu Cys Gly His Arg Leu 
                1525                1530                1535


Ile Ile Phe Thr Gln Ser Val Lys Ser Met Tyr Leu Lys Tyr Leu Lys 
            1540                1545                1550


Ile Glu Glu Thr Asn Pro Ser Leu Ala Gln Asp Thr Val Ile Ile Lys 
        1555                1560                1565


Lys Lys Ser Cys Ser Ser Lys Ala Leu Asn Thr Pro Val Leu Ser Val 
    1570                1575                1580


Leu Lys Glu Ala Ala Lys Leu Met Lys Thr Cys Ser Ser Ser Asn Lys 
1585                1590                1595                1600


Lys Leu Pro Ser Asp Glu Pro Lys Ser Ser Cys Ile Leu Gln Ile Thr 
                1605                1610                1615


Val Glu Glu Phe His His Val Phe Arg Arg Ile Ala Asp Leu Gln Ser 
            1620                1625                1630


Pro Leu Phe Arg Gly Pro Asp Asp Asp Pro Ala Ala Leu Phe Glu Met 
        1635                1640                1645


Ala Lys Ser Gly Gln Ser Lys Lys Pro Ser Asp Glu Leu Ser Gln Lys 
    1650                1655                1660


Thr Val Glu Cys Thr Thr Trp Leu Leu Cys Thr Cys Met Asp Thr Gly 
1665                1670                1675                1680


Glu Ala Leu Lys Phe Ser Leu Ser Glu Ser Gly Arg Arg Leu Gly Leu 
                1685                1690                1695


Val Pro Cys Gly Ala Val Gly Val Gln Leu Ser Glu Ile Gln Asp Gln 
            1700                1705                1710


Lys Trp Thr Val Lys Pro His Ile Gly Glu Val Phe Cys Tyr Leu Pro 
        1715                1720                1725


Leu Arg Ile Lys Thr Gly Leu Pro Val His Ile Asn Gly Cys Phe Ala 
    1730                1735                1740


Val Thr Ser Asn Arg Lys Glu Ile Trp Lys Thr Asp Thr Lys Gly Arg 
1745                1750                1755                1760


Trp Asn Thr Thr Phe Met Arg His Val Ile Val Lys Ala Tyr Leu Gln 
                1765                1770                1775


Val Leu Ser Val Leu Arg Asp Leu Ala Thr Ser Gly Glu Leu Met Asp 
            1780                1785                1790


Tyr Thr Tyr Tyr Ala Val Trp Pro Asp Pro Asp Leu Val His Asp Asp 
        1795                1800                1805


Phe Ser Val Ile Cys Gln Gly Phe Tyr Glu Asp Ile Ala His Gly Lys 
    1810                1815                1820


Gly Lys Glu Leu Thr Lys Val Phe Ser Asp Gly Ser Thr Trp Val Ser 
1825                1830                1835                1840


Met Lys Asn Val Arg Phe Leu Asp Asp Ser Ile Leu Lys Arg Arg Asp 
                1845                1850                1855


Val Gly Ser Ala Ala Phe Lys Ile Phe Leu Lys Tyr Leu Lys Lys Thr 
            1860                1865                1870


Gly Ser Lys Asn Leu Cys Ala Val Glu Leu Pro Ser Ser Val Lys Leu 
        1875                1880                1885


Gly Phe Glu Glu Ala Gly Cys Lys Gln Ile Leu Leu Glu Asn Thr Phe 
    1890                1895                1900


Ser Glu Lys Gln Phe Phe Ser Glu Val Phe Phe Pro Asn Ile Gln Glu 
1905                1910                1915                1920


Ile Glu Ala Glu Leu Arg Asp Pro Leu Met Ile Phe Val Leu Asn Glu 
                1925                1930                1935


Lys Val Asp Glu Phe Ser Gly Val Leu Arg Val Thr Pro Cys Ile Pro 
            1940                1945                1950


Cys Ser Leu Glu Gly His Pro Leu Val Leu Pro Ser Arg Leu Ile His 
        1955                1960                1965


Pro Glu Gly Arg Val Ala Lys Leu Phe Asp Ile Lys Asp Gly Arg Phe 
    1970                1975                1980


Pro Tyr Gly Ser Thr Gln Asp Tyr Leu Asn Pro Ile Ile Leu Ile Lys 
1985                1990                1995                2000


Leu Val Gln Leu Gly Met Ala Lys Asp Asp Ile Leu Trp Asp Asp Met 
                2005                2010                2015


Leu Glu Arg Ala Val Ser Val Ala Glu Ile Asn Lys Ser Asp His Val 
            2020                2025                2030


Ala Ala Cys Leu Arg Ser Ser Ile Leu Leu Ser Leu Ile Asp Glu Lys 
        2035                2040                2045


Leu Lys Ile Arg Asp Pro Arg Ala Lys Asp Phe Ala Ala Lys Tyr Gln 
    2050                2055                2060


Thr Ile Arg Phe Leu Pro Phe Leu Thr Lys Pro Ala Gly Phe Ser Leu 
2065                2070                2075                2080


Asp Trp Lys Gly Asn Ser Phe Lys Pro Glu Thr Met Phe Ala Ala Thr 
                2085                2090                2095


Asp Leu Tyr Thr Ala Glu His Gln Asp Ile Val Cys Leu Leu Gln Pro 
            2100                2105                2110


Ile Leu Asn Glu Asn Ser His Ser Phe Arg Gly Cys Gly Ser Val Ser 
        2115                2120                2125


Leu Ala Val Lys Glu Phe Leu Gly Leu Leu Lys Lys Pro Thr Val Asp 
    2130                2135                2140


Leu Val Ile Asn Gln Leu Lys Glu Val Ala Lys Ser Val Asp Asp Gly 
2145                2150                2155                2160


Ile Thr Leu Tyr Gln Glu Asn Ile Thr Asn Ala Cys Tyr Lys Tyr Leu 
                2165                2170                2175


His Glu Ala Leu Met Gln Asn Glu Ile Thr Lys Met Ser Ile Ile Asp 
            2180                2185                2190


Lys Leu Lys Pro Phe Ser Phe Ile Leu Val Glu Asn Ala Tyr Val Asp 
        2195                2200                2205


Ser Glu Lys Val Ser Phe His Leu Asn Phe Glu Ala Ala Pro Tyr Leu 
    2210                2215                2220


Tyr Gln Leu Pro Asn Lys Tyr Lys Asn Asn Phe Arg Glu Leu Phe Glu 
2225                2230                2235                2240


Thr Val Gly Val Arg Gln Ser Cys Thr Val Glu Asp Phe Ala Leu Val 
                2245                2250                2255


Leu Glu Ser Ile Asp Gln Glu Arg Gly Thr Lys Gln Ile Thr Glu Glu 
            2260                2265                2270


Asn Phe Gln Leu Cys Arg Arg Ile Ile Ser Glu Gly Ile Trp Ser Leu 
        2275                2280                2285


Ile Arg Glu Lys Lys Gln Glu Phe Cys Glu Lys Asn Tyr Gly Lys Ile 
    2290                2295                2300


Leu Leu Pro Asp Thr Asn Leu Met Leu Leu Pro Ala Lys Ser Leu Cys 
2305                2310                2315                2320


Tyr Asn Asp Cys Pro Trp Ile Lys Val Lys Asp Thr Thr Val Lys Tyr 
                2325                2330                2335


Cys His Ala Asp Ile Pro Arg Glu Val Ala Val Lys Leu Gly Ala Val 
            2340                2345                2350


Pro Lys Arg His Lys Ala Leu Glu Arg Tyr Ala Ser Asn Val Cys Phe 
        2355                2360                2365


Thr Thr Leu Gly Thr Glu Phe Gly Gln Lys Glu Lys Leu Thr Ser Arg 
    2370                2375                2380


Ile Lys Ser Ile Leu Asn Ala Tyr Pro Ser Glu Lys Glu Met Leu Lys 
2385                2390                2395                2400


Glu Leu Leu Gln Asn Ala Asp Asp Ala Lys Ala Thr Glu Ile Cys Phe 
                2405                2410                2415


Val Phe Asp Pro Arg Gln His Pro Val Asp Arg Ile Phe Asp Asp Lys 
            2420                2425                2430


Trp Ala Pro Leu Gln Gly Pro Ala Leu Cys Val Tyr Asn Asn Gln Pro 
        2435                2440                2445


Phe Thr Glu Asp Asp Val Arg Gly Ile Gln Asn Leu Gly Lys Gly Thr 
    2450                2455                2460


Lys Glu Gly Asn Pro Tyr Lys Thr Gly Gln Tyr Gly Ile Gly Phe Asn 
2465                2470                2475                2480


Ser Val Tyr His Ile Thr Asp Cys Pro Ser Phe Ile Ser Gly Asn Asp 
                2485                2490                2495


Ile Leu Cys Ile Phe Asp Pro His Ala Arg Tyr Ala Pro Gly Ala Thr 
            2500                2505                2510


Ser Ile Ser Pro Gly Arg Met Phe Arg Asp Leu Asp Ala Asp Phe Arg 
        2515                2520                2525


Thr Gln Phe Ser Asp Val Leu Asp Leu Tyr Leu Gly Thr His Phe Lys 
    2530                2535                2540


Leu Asp Asn Cys Thr Met Phe Arg Phe Pro Leu Arg Asn Ala Glu Met 
2545                2550                2555                2560


Ala Lys Val Ser Glu Ile Ser Ser Val Pro Ala Ser Asp Arg Met Val 
                2565                2570                2575


Gln Asn Leu Leu Asp Lys Leu Arg Ser Asp Gly Ala Glu Leu Leu Met 
            2580                2585                2590


Phe Leu Asn His Met Glu Lys Ile Ser Ile Cys Glu Ile Asp Lys Ser 
        2595                2600                2605


Thr Gly Ala Leu Asn Val Leu Tyr Ser Val Lys Gly Lys Ile Thr Asp 
    2610                2615                2620


Gly Asp Arg Leu Lys Arg Lys Gln Phe His Ala Ser Val Ile Asp Ser 
2625                2630                2635                2640


Val Thr Lys Lys Arg Gln Leu Lys Asp Ile Pro Val Gln Gln Ile Thr 
                2645                2650                2655


Tyr Thr Met Asp Thr Glu Asp Ser Glu Gly Asn Leu Thr Thr Trp Leu 
            2660                2665                2670


Ile Cys Asn Arg Ser Gly Phe Ser Ser Met Glu Lys Val Ser Lys Ser 
        2675                2680                2685


Val Ile Ser Ala His Lys Asn Gln Asp Ile Thr Leu Phe Pro Arg Gly 
    2690                2695                2700


Gly Val Ala Ala Cys Ile Thr His Asn Tyr Lys Lys Pro His Arg Ala 
2705                2710                2715                2720


Phe Cys Phe Leu Pro Leu Ser Leu Glu Thr Gly Leu Pro Phe His Val 
                2725                2730                2735


Asn Gly His Phe Ala Leu Asp Ser Ala Arg Arg Asn Leu Trp Arg Asp 
            2740                2745                2750


Asp Asn Gly Val Gly Val Arg Ser Asp Trp Asn Asn Ser Leu Met Thr 
        2755                2760                2765


Ala Leu Ile Ala Pro Ala Tyr Val Glu Leu Leu Ile Gln Leu Lys Lys 
    2770                2775                2780


Arg Tyr Phe Pro Gly Ser Asp Pro Thr Leu Ser Val Leu Gln Asn Thr 
2785                2790                2795                2800


Pro Ile His Val Val Lys Asp Thr Leu Lys Lys Phe Leu Ser Phe Phe 
                2805                2810                2815


Pro Val Asn Arg Leu Asp Leu Gln Pro Asp Leu Tyr Cys Leu Val Lys 
            2820                2825                2830


Ala Leu Tyr Asn Cys Ile His Glu Asp Met Lys Arg Leu Leu Pro Val 
        2835                2840                2845


Val Arg Ala Pro Asn Ile Asp Gly Ser Asp Leu His Ser Ala Val Ile 
    2850                2855                2860


Ile Thr Trp Ile Asn Met Ser Thr Ser Asn Lys Thr Arg Pro Phe Phe 
2865                2870                2875                2880


Asp Asn Leu Leu Gln Asp Glu Leu Gln His Leu Lys Asn Ala Asp Tyr 
                2885                2890                2895


Asn Ile Thr Thr Arg Lys Thr Val Ala Glu Asn Val Tyr Arg Leu Lys 
            2900                2905                2910


His Leu Leu Leu Glu Ile Gly Phe Asn Leu Val Tyr Asn Cys Asp Glu 
        2915                2920                2925


Thr Ala Asn Leu Tyr His Cys Leu Ile Asp Ala Asp Ile Pro Val Ser 
    2930                2935                2940


Tyr Val Thr Pro Ala Asp Ile Arg Ser Phe Leu Met Thr Phe Ser Ser 
2945                2950                2955                2960


Pro Asp Thr Asn Cys His Ile Gly Lys Leu Pro Cys Arg Leu Gln Gln 
                2965                2970                2975


Thr Asn Leu Lys Leu Phe His Ser Leu Lys Leu Leu Val Asp Tyr Cys 
            2980                2985                2990


Phe Lys Asp Ala Glu Glu Asn Glu Ile Glu Val Glu Gly Leu Pro Leu 
        2995                3000                3005


Leu Ile Thr Leu Asp Ser Val Leu Gln Thr Phe Asp Ala Lys Arg Pro 
    3010                3015                3020


Lys Phe Leu Thr Thr Tyr His Glu Leu Ile Pro Ser Arg Lys Asp Leu 
3025                3030                3035                3040


Phe Met Asn Thr Leu Tyr Leu Lys Tyr Ser Asn Ile Leu Leu Asn Cys 
                3045                3050                3055


Lys Val Ala Lys Val Phe Asp Ile Ser Ser Phe Ala Asp Leu Leu Ser 
            3060                3065                3070


Ser Val Leu Pro Arg Glu Tyr Lys Thr Lys Ser Cys Thr Lys Trp Lys 
        3075                3080                3085


Asp Asn Phe Ala Ser Glu Ser Trp Leu Lys Asn Ala Trp His Phe Ile 
    3090                3095                3100


Ser Glu Ser Val Ser Val Lys Glu Asp Gln Glu Glu Thr Lys Pro Thr 
3105                3110                3115                3120


Phe Asp Ile Val Val Asp Thr Leu Lys Asp Trp Ala Leu Leu Pro Gly 
                3125                3130                3135


Thr Lys Phe Thr Val Ser Ala Asn Gln Leu Val Val Pro Glu Gly Asp 
            3140                3145                3150


Val Leu Leu Pro Leu Ser Leu Met His Ile Ala Val Phe Pro Asn Ala 
        3155                3160                3165


Gln Ser Asp Lys Val Phe His Ala Leu Met Lys Ala Gly Cys Ile Gln 
    3170                3175                3180


Leu Ala Leu Asn Lys Ile Cys Ser Lys Asp Ser Ala Phe Val Pro Leu 
3185                3190                3195                3200


Leu Ser Cys His Thr Ala Asn Ile Glu Ser Pro Thr Ser Ile Leu Lys 
                3205                3210                3215


Ala Leu His Tyr Met Val Gln Thr Ser Thr Phe Arg Ala Glu Lys Leu 
            3220                3225                3230


Val Glu Asn Asp Phe Glu Ala Leu Leu Met Tyr Phe Asn Cys Asn Leu 
        3235                3240                3245


Asn His Leu Met Ser Gln Asp Asp Ile Lys Ile Leu Lys Ser Leu Pro 
    3250                3255                3260


Cys Tyr Lys Ser Ile Ser Gly Arg Tyr Val Ser Ile Gly Lys Phe Gly 
3265                3270                3275                3280


Thr Cys Tyr Val Leu Thr Lys Ser Ile Pro Ser Ala Glu Val Glu Lys 
                3285                3290                3295


Trp Thr Gln Ser Ser Ser Ser Ala Phe Leu Glu Glu Lys Ile His Leu 
            3300                3305                3310


Lys Glu Leu Tyr Glu Val Ile Gly Cys Val Pro Val Asp Asp Leu Glu 
        3315                3320                3325


Val Tyr Leu Lys His Leu Leu Pro Lys Ile Glu Asn Leu Ser Tyr Asp 
    3330                3335                3340


Ala Lys Leu Glu His Leu Ile Tyr Leu Lys Asn Arg Leu Ser Ser Ala 
3345                3350                3355                3360


Glu Glu Leu Ser Glu Ile Lys Glu Gln Leu Phe Glu Lys Leu Glu Ser 
                3365                3370                3375


Leu Leu Ile Ile His Asp Ala Asn Ser Arg Leu Lys Gln Ala Lys His 
            3380                3385                3390


Phe Tyr Asp Arg Thr Val Arg Val Phe Glu Val Met Leu Pro Glu Lys 
        3395                3400                3405


Leu Phe Ile Pro Asn Asp Phe Phe Lys Lys Leu Glu Gln Leu Ile Lys 
    3410                3415                3420


Pro Lys Asn His Val Thr Phe Met Thr Ser Trp Val Glu Phe Leu Arg 
3425                3430                3435                3440


Asn Ile Gly Leu Lys Tyr Ile Leu Ser Gln Gln Gln Leu Leu Gln Phe 
                3445                3450                3455


Ala Lys Glu Ile Ser Val Arg Ala Asn Thr Glu Asn Trp Ser Lys Glu 
            3460                3465                3470


Thr Leu Gln Asn Thr Val Asp Ile Leu Leu His His Ile Phe Gln Glu 
        3475                3480                3485


Arg Met Asp Leu Leu Ser Gly Asn Phe Leu Lys Glu Leu Ser Leu Ile 
    3490                3495                3500


Pro Phe Leu Cys Pro Glu Arg Ala Pro Ala Glu Phe Ile Arg Phe His 
3505                3510                3515                3520


Pro Gln Tyr Gln Glu Val Asn Gly Thr Leu Pro Leu Ile Lys Phe Asn 
                3525                3530                3535


Gly Ala Gln Val Asn Pro Lys Phe Lys Gln Cys Asp Val Leu Gln Leu 
            3540                3545                3550


Leu Trp Thr Ser Cys Pro Ile Leu Pro Glu Lys Ala Thr Pro Leu Ser 
        3555                3560                3565


Ile Lys Glu Gln Glu Gly Ser Asp Leu Gly Pro Gln Glu Gln Leu Glu 
    3570                3575                3580


Gln Val Leu Asn Met Leu Asn Val Asn Leu Asp Pro Pro Leu Asp Lys 
3585                3590                3595                3600


Val Ile Asn Asn Cys Arg Asn Ile Cys Asn Ile Thr Thr Leu Asp Glu 
                3605                3610                3615


Glu Met Val Lys Thr Arg Ala Lys Val Leu Arg Ser Ile Tyr Glu Phe 
            3620                3625                3630


Leu Ser Ala Glu Lys Arg Glu Phe Arg Phe Gln Leu Arg Gly Val Ala 
        3635                3640                3645


Phe Val Met Val Glu Asp Gly Trp Lys Leu Leu Lys Pro Glu Glu Val 
    3650                3655                3660


Val Ile Asn Leu Glu Tyr Glu Ser Asp Phe Lys Pro Tyr Leu Tyr Lys 
3665                3670                3675                3680


Leu Pro Leu Glu Leu Gly Thr Phe His Gln Leu Phe Lys His Leu Gly 
                3685                3690                3695


Thr Glu Asp Ile Ile Ser Thr Lys Gln Tyr Val Glu Val Leu Ser Arg 
            3700                3705                3710


Ile Phe Lys Asn Ser Glu Gly Lys Gln Leu Asp Pro Asn Glu Met Arg 
        3715                3720                3725


Thr Val Lys Arg Val Val Ser Gly Leu Phe Arg Ser Leu Gln Asn Asp 
    3730                3735                3740


Ser Val Lys Val Arg Ser Asp Leu Glu Asn Val Arg Asp Leu Ala Leu 
3745                3750                3755                3760


Tyr Leu Pro Ser Gln Asp Gly Arg Leu Val Lys Ser Ser Ile Leu Val 
                3765                3770                3775


Phe Asp Asp Ala Pro His Tyr Lys Ser Arg Ile Gln Gly Asn Ile Gly 
            3780                3785                3790


Val Gln Met Leu Val Asp Leu Ser Gln Cys Tyr Leu Gly Lys Asp His 
        3795                3800                3805


Gly Phe His Thr Lys Leu Ile Met Leu Phe Pro Gln Lys Leu Arg Pro 
    3810                3815                3820


Arg Leu Leu Ser Ser Ile Leu Glu Glu Gln Leu Asp Glu Glu Thr Pro 
3825                3830                3835                3840


Lys Val Cys Gln Phe Gly Ala Leu Cys Ser Leu Gln Gly Arg Leu Gln 
                3845                3850                3855


Leu Leu Leu Ser Ser Glu Gln Phe Ile Thr Gly Leu Ile Arg Ile Met 
            3860                3865                3870


Lys His Glu Asn Asp Asn Ala Phe Leu Ala Asn Glu Glu Lys Ala Ile 
        3875                3880                3885


Arg Leu Cys Lys Ala Leu Arg Glu Gly Leu Lys Val Ser Cys Phe Glu 
    3890                3895                3900


Lys Leu Gln Thr Thr Leu Arg Val Lys Gly Phe Asn Pro Ile Pro His 
3905                3910                3915                3920


Ser Arg Ser Glu Thr Phe Ala Phe Leu Lys Arg Phe Gly Asn Ala Val 
                3925                3930                3935


Ile Leu Leu Tyr Ile Gln His Ser Asp Ser Lys Asp Ile Asn Phe Leu 
            3940                3945                3950


Leu Ala Leu Ala Met Thr Leu Lys Ser Ala Thr Asp Asn Leu Ile Ser 
        3955                3960                3965


Asp Thr Ser Tyr Leu Ile Ala Met Leu Gly Cys Asn Asp Ile Tyr Arg 
    3970                3975                3980


Ile Gly Glu Lys Leu Asp Ser Leu Gly Val Lys Tyr Asp Ser Ser Glu 
3985                3990                3995                4000


Pro Ser Lys Leu Glu Leu Pro Met Pro Gly Thr Pro Ile Pro Ala Glu 
                4005                4010                4015


Ile His Tyr Thr Leu Leu Met Asp Pro Met Asn Val Phe Tyr Pro Gly 
            4020                4025                4030


Glu Tyr Val Gly Tyr Leu Val Asp Ala Glu Gly Gly Asp Ile Tyr Gly 
        4035                4040                4045


Ser Tyr Gln Pro Thr Tyr Thr Tyr Ala Ile Ile Val Gln Glu Val Glu 
    4050                4055                4060


Arg Glu Asp Ala Asp Asn Ser Ser Phe Leu Gly Lys Ile Tyr Gln Ile 
4065                4070                4075                4080


Asp Ile Gly Tyr Ser Glu Tyr Lys Ile Val Ser Ser Leu Asp Leu Tyr 
                4085                4090                4095


Lys Phe Ser Arg Pro Glu Glu Ser Ser Gln Ser Arg Asp Ser Ala Pro 
            4100                4105                4110


Ser Thr Pro Thr Ser Pro Thr Glu Phe Leu Thr Pro Gly Leu Arg Ser 
        4115                4120                4125


Ile Pro Pro Leu Phe Ser Gly Arg Glu Ser His Lys Thr Ser Ser Lys 
    4130                4135                4140


His Gln Ser Pro Lys Lys Leu Lys Val Asn Ser Leu Pro Glu Ile Leu 
4145                4150                4155                4160


Lys Glu Val Thr Ser Val Val Glu Gln Ala Trp Lys Leu Pro Glu Ser 
                4165                4170                4175


Glu Arg Lys Lys Ile Ile Arg Arg Leu Tyr Leu Lys Trp His Pro Asp 
            4180                4185                4190


Lys Asn Pro Glu Asn His Asp Ile Ala Asn Glu Val Phe Lys His Leu 
        4195                4200                4205


Gln Asn Glu Ile Asn Arg Leu Glu Lys Gln Ala Phe Leu Asp Gln Asn 
    4210                4215                4220


Ala Asp Arg Ala Ser Arg Arg Thr Phe Ser Thr Ser Ala Ser Arg Phe 
4225                4230                4235                4240


Gln Ser Asp Lys Tyr Ser Phe Gln Arg Phe Tyr Thr Ser Trp Asn Gln 
                4245                4250                4255


Glu Ala Thr Ser His Lys Ser Glu Arg Gln Gln Gln Asn Lys Glu Lys 
            4260                4265                4270


Cys Pro Pro Ser Ala Gly Gln Thr Tyr Ser Gln Arg Phe Phe Val Pro 
        4275                4280                4285


Pro Thr Phe Lys Ser Val Gly Asn Pro Val Glu Ala Arg Arg Trp Leu 
    4290                4295                4300


Arg Gln Ala Arg Ala Asn Phe Ser Ala Ala Arg Asn Asp Leu His Lys 
4305                4310                4315                4320


Asn Ala Asn Glu Trp Val Cys Phe Lys Cys Tyr Leu Ser Thr Lys Leu 
                4325                4330                4335


Ala Leu Ile Ala Ala Asp Tyr Ala Val Arg Gly Lys Ser Asp Lys Asp 
            4340                4345                4350


Val Lys Pro Thr Ala Leu Ala Gln Lys Ile Glu Glu Tyr Ser Gln Gln 
        4355                4360                4365


Leu Glu Gly Leu Thr Asn Asp Val His Thr Leu Glu Ala Tyr Gly Val 
    4370                4375                4380


Asp Ser Leu Lys Thr Arg Tyr Pro Asp Leu Leu Pro Phe Pro Gln Ile 
4385                4390                4395                4400


Pro Asn Asp Arg Phe Thr Ser Glu Val Ala Met Arg Val Met Glu Cys 
                4405                4410                4415


Thr Ala Cys Ile Ile Ile Lys Leu Glu Asn Phe Met Gln Gln Lys Val 
            4420                4425                4430


<210>  8236
<211>  7396
<212>  DNA
<213>  Homo sapiens

<400>  8236
ctgctcctcg gccgccgcgg cttcctctag cgtttcctcc tcggcgcggg ctgctgcgta     60

cgggactgcg ccatgcggat cccgccctcc cggcccgcgc ggggcctgtg gacgcggtag    120

ggccggccgt gatcgggcgc cggcgtcagg ggcgggcgct aggggcgcct gccgcgccgc    180

gatgtgggag aggtgggtcc cggtgaccgt gctccccggc tgcgtgggct gcaggaccgt    240

cgcggcgctg gcgtcctgga ccgtgcgcga tgtgaaggaa cgtatcttcg cggagactgg    300

cttcccggtg tcggagcagc ggctgtggcg cggcggccgc gaggtcgatt tggtcagaca    360

acgccaccac ttgttgattt tctcaaggac attttgagaa gatatccaga aggaggacag    420

attcttaagg aattaattca gaatgcagaa gatgctgggg cgacagaagt taaattttta    480

tatgatgaaa ctcaatacgg aacagagact ctttggtcaa aagatatggc gccatatcag    540

gggccagctc tctatgtgta caacaacgcg gttttcaccc cagaggactg gcacggcatt    600

caagaaatag caagaagcag gaaaaaggat gatcctctga aggtcggaag atttggaatt    660

gggtttaatt ctgtctatca tataacagat gttccttgta tctttagtgg tgaccaaatc    720

gggatgctag atcctcatca aacacttttt ggcccacatg aatcaggcca atgttggaat    780

ctcaaagatg acagcaaaga aattagtgaa ctttcagacc agtttgcacc atttgttggc    840

atttttggaa gcaccaagga aacatttata aacggcaatt ttccaggaac atttttccgt    900

ttccctcttc gcctacaacc ttcacaactt agtagtaacc tctacaataa gcagaaggtt    960

cttgagttgt ttgagtcttt tagggcagat gcagacacag tgctgctctt tctgaaaagt   1020

gtgcaggatg tttccttata tgtccgagag gctgacggaa cagagaaact ggtgtttaga   1080

gtgacttcga gtgagagtaa ggcactgaaa catgagcggc cgaattctat aaagattctg   1140

ggaactgcta taagtaacta ttgtaaaaag actccaagca ataacatcac ctgtgtaaca   1200

tatcacgtaa atattgtttt agaagaggag agtactaagg atgcacagaa aacatcttgg   1260

ttggtgtgta acagtgtggg tgggcgaggg atcagtagta agcttgactc tttagctgat   1320

gaactgaaat ttgtcccaat cattggaata gccatgcctt tatcaagcag agatgatgaa   1380

gcaaaaggag caacgtctga tttctcagga aaagcatttt gtttccttcc tttaccacct   1440

ggtgaggaaa gcagcacagg cctcccagtt cacatcagtg ggttctttgg ccttactgat   1500

aaccgcagga gcataaaatg gagagagctg gaccagtgga gagacccggc agccttatgg   1560

aatgagtttc ttgtcatgaa tgttgtcccc aaagcttatg ctactctgat cttagattca   1620

ataaaacgtc tggagatgga aaagagctct gatttcccct tgtcagttga tgttatctat   1680

aagctttggc cggaggcgag caaagtcaag gtgcactggc aaccggtgtt agagcctcta   1740

ttcagcgagc tgttgcagaa tgcagtgatt tattcaatta gctgtgactg ggtcaggttg   1800

gagcaggtgt acttctcaga acttgatgaa aatttagaat acacaaaaac tgtgctcaac   1860

tacctccaga gctcagggaa gcagattgcc aaggtaccag ggaatgtgga tgctgctgtt   1920

cagctcacag ctgcctctgg cacaacacct gtgaggaagg tgacgcccgc gtgggtgcgg   1980

caggtgctgc ggaagtgtgc acacctgggc tgtgctgaag aaaagcttca ccttctagaa   2040

tttgtgcttt ctgaccaagc ctacagtgag ctgcttgggc tggagctgct ccctttacaa   2100

aatggcaatt ttgtcccctt ctcctcatct gtatcagacc aagatgtcat ttatattacc   2160

tcagcagaat atccaaggtc ccttttccca agtcttgaag gaagatttat tttggataac   2220

ttgaaacctc accttgtggc tgctttaaag gaagctgccc aaacccgagg aagaccatgt   2280

actcagctgc agcttctaaa tccagaacga tttgcacgtc ttatcaagga agtaatgaat   2340

acattctggc ctggcagaga attgattgtt caatggtatc catttgatga aaacagaaat   2400

cacccatctg tttcatggct taagatggtt tggaaaaatc tttatataca tttttcagag   2460

gatttgactt tatttgatga gatgccactt atccccagaa ctatactaga ggaaggtcag   2520

acatgtgtgg aactcattag actcaggatt ccatcgttag tcattttaga cgatgaatct   2580

gaagcacagc ttccagaatt tttagcagac attgtacaaa aacttggagg gtttgtcctt   2640

aaaaaattag atgcatctat acaacatccg cttattaaaa aatatattca ttcaccatta   2700

ccaagtgctg ttttgcagat aatggagaag atgccattgc agaaattgtg taatcaaata   2760

acttcgctac ttccaacaca caaagatgcc ctgaggaagt tcttggctag tttaaccgat   2820

agcagtgaga aagagaaaag aattattcaa gaattggcaa tattcaagcg cattaaccat   2880

tcttctgatc agggaatttc ctcttataca aaattgaaag gttgtaaagt cttacaccat   2940

actgccaaac tcccagcaga tctgcgactt tctatttcag taatagacag tagtgatgaa   3000

gctactattc gtctggcaaa catgttgaaa atagaacagt taaagaccac tagctgctta   3060

aagcttgttt taaaagatat tgaaaatgca ttttattcac atgaagaggt aacacagctt   3120

atgttatggg tccttgagaa tctatcttct cttaaaaatg agaatccaaa tgtgcttgag   3180

tggttaacac cattaaaatt catccagata tcacaggaac agatggtatc agctggtgaa   3240

ctctttgacc ctgatataga agtactaaag gatctctttt gtaatgaaga aggaacctat   3300

ttcccaccct cagtttttac ctcaccagat attcttcact ccttaagaca gattggttta   3360

aaaaacgaag ccagtctcaa agaaaaggat gttgtgcaag tggcaaaaaa aattgaagcc   3420

ttacaggtcg gtgcttgtcc tgatcaagat gttcttctga agaaagccaa aaccctctta   3480

ctggttttaa ataagaatca cacactgttg caatcatctg aaggaaagat gacattgaag   3540

aaaataaaat gggttccagc ctgcaaggaa aggcctccaa attatccagg ctctttggtc   3600

tggaaaggag atctctgtaa tctctgtgca ccaccagata tgtgtgatgt aggccatgca   3660

attctcattg gctcctcact tcctcttgtt gaaagtatcc atgtaaacct ggaaaaagca   3720

ttagggatct tcacaaaacc tagccttagt gctgtcttaa aacactttaa aattgttgtt   3780

gattggtatt cttcaaaaac ctttagtgat gaagactact atcaattcca gcatattttg   3840

cttgagattt acggattcat gcatgatcat ctaaatgaag ggaaagattc ttttagagcc   3900

ttaaaatttc catgggtttg gactggcaaa aagttttgtc cacttgccca ggctgtgatt   3960

aaaccaatcc atgatcttga ccttcagcct tatttgcata atgtacctaa aaccatggca   4020

aaattccacc aactatttaa ggtctgtggt tcaatagagg agttgacatc agatcatatt   4080

tccatggtta ttcagaagat atatctcaaa agtgaccaag atctcagtga acaagaaagc   4140

aaacaaaatc ttcatcttat gttgaatatt atcagatggc tgtatagcaa tcagattcca   4200

gcaagcccca acacaccagt tcctatacat catagcaaaa atccttctaa acttatcatg   4260

aagccaattc acgaatgctg ttattgtgac attaaagttg atgaccttaa tgacttactt   4320

gaagattctg tggaaccaat cattttggtg catgaggaca tacccatgaa aactgcagaa   4380

tggctaaaag ttccatgcct tagtacaaga ctgataaatc ctgaaaacat gggatttgag   4440

cagtcaggac aaagagagcc acttactgta agaattaaaa atattctgga agaataccct   4500

tcagtgtcag atatttttaa agaactactt caaaacgctg atgatgcaaa tgcaacagaa   4560

tgcagtttct tgattgatat gagaagaaat atggacataa gagagaatct cctagaccca   4620

gggatggcag cttgtcatgg acctgctttg tggtcattca acaattctca attctcagat   4680

tcagattttg tgaacataac taggttagga gaatctttaa aaaggggaga agttgacaaa   4740

gttggaaaat ttggtcttgg atttaattct gtgtaccata tcactgacat tcccatcatt   4800

atgagtcggg aattcatgat aatgttcgat ccaaacataa atcatatcag taaacacatt   4860

aaagacaaat ccaatcctgg gatcaaaatt aattggagta aacaacagaa aagacttaga   4920

aaatttccta atcagttcaa accatttata gatgtatttg gctgtcagtt acctttgact   4980

gtagaagcac cttacagcta taatggaacc cttttccgac tgtcctttag aactcaacag   5040

gaagcaaaag tgagtgaagt tagtagtacg tgctacaata cagcagatat ttattctctt   5100

gtggatgaat ttagtctctg tggacacagg cttatcattt tcactcagag tgtaaagtca   5160

atgtatttga agtacttgaa aattgaggaa accaacccca gtttagcaca agatacagta   5220

ataattaaaa aaaaatcctg ctcttccaaa gcattgaaca cacctgtctt aagtgtttta   5280

aaagaggctg ctaagctcat gaagacttgc agcagcagta ataaaaagct tcccagtgat   5340

gaaccaaagt catcttgcat tcttcagatc acagtggaag aatttcacca tgtgttcaga   5400

aggattgctg atttacagtc gccacttttt agaggtccag atgatgaccc agctgctctc   5460

tttgaaatgg ctaagtctgg ccaatcaaaa aagccatcag atgagttgtc acagaaaaca   5520

gtagagtgta ccacgtggct tctgtgtact tgcatggaca caggagaggc tctgaagttt   5580

tccctgagtg agagtggaag aagactagga ctggttccat gtggggcagt aggagttcag   5640

ctgtcagaaa tccaggacca gaagtggaca gtgaaaccac acattggaga ggtgttttgc   5700

tatttacctt tacgaataaa aacaggcttg ccagttcata tcaatgggtg ctttgctgtt   5760

acatcaaata ggaaagaaat ctggaaaaca gatacaaaag gacgatggaa taccacgttc   5820

atgagacatg ttattgtgaa agcttactta caggtactga gtgtcttacg ggacctggcc   5880

actagtgggg agctaatgga ttatacttac tatgcagtat ggcccgatcc tgatttagtt   5940

catgatgatt tttctgtaat ttgccaagga ttttatgaag atatagctca tggaaaaggg   6000

aaagaactga ccaaagtctt ctctgatgga tctacttggg tttccatgaa gaacgtaaga   6060

tttctagatg actctatact taaaagaaga gatgttggtt cagcagcctt caagatattt   6120

ttgaaatacc tcaagaagac tgggtccaaa aacctttgtg ctgttgaact tccttcttcg   6180

gtaaaattag gatttgaaga agctggctgc aaacagatac tacttgaaaa cacattttca   6240

gagaaacagt ttttttctga agtgtttttt ccaaatattc aagaaattga agcagaactt   6300

agagatcctt taatgatctt tgttctaaat gaaaaagttg atgagttctc gggagttctt   6360

cgtgttactc catgtattcc ttgttccttg gaggggcatc ctttggtttt gccatcaaga   6420

ttgatccacc ccgaaggacg agttgcaaag ttatttgata ttaaagatgg gagattccct   6480

tatggttcta ctcaggatta tctcaatcct attattttga ttaaactagt tcagttaggt   6540

atggcaaaag atgatatttt atgggatgat atgctagaac gtgcagtgtc agtagctgaa   6600

attaataaaa gtgatcatgt tgctgcatgc ctaagaagta gtatcttatt gagtcttatc   6660

gatgagaaac taaaaataag ggatcctaga gcaaaggatt ttgctgcaaa atatcaaaca   6720

atccgcttcc ttccatttct gacaaaacca gcaggttttt ctttggactg gaaaggcaac   6780

agttttaagc ctgaaaccat gtttgcagca actgaccttt atacagctga acatcaagat   6840

atagtttgtc ttttgcaacc aattctaaat gaaaattccc attcttttag aggttgtggt   6900

tcagtgtcat tggctgttaa agagtttttg ggattactca agaagccaac agttgatctg   6960

gttataaacc aattgaaaga agtagcaaaa tcagttgatg atggaattac actgtaccag   7020

gagaatatca ccaatgcttg ctacaaatac cttcatgaag ccttgatgca aaatgaaatc   7080

actaagatgt caattattga taagttaaaa ccctttagct tcattctagt tgagaatgca   7140

tatgttgact cagaaaaggt ttcttttcat ttaaattttg aggcggcacc atacctttat   7200

cagttgccta ataagtataa aaataatttc cgcgaacttt ttgaaaccgt gggtgtgagg   7260

cagtcatgca ctgttgaaga ttttgctctt gttttggaat ctattgatca agaaagagga   7320

acaaagcaaa taacagaaga gaattttcag ctttgccgac gaataatcag tgaaggaata   7380

tggagtctca ttagag                                                   7396


<210>  8237
<211>  2289
<212>  PRT
<213>  Homo sapiens

<400>  8237

Met Ala Pro Tyr Gln Gly Pro Ala Leu Tyr Val Tyr Asn Asn Ala Val 
1               5                   10                  15


Phe Thr Pro Glu Asp Trp His Gly Ile Gln Glu Ile Ala Arg Ser Arg 
            20                  25                  30


Lys Lys Asp Asp Pro Leu Lys Val Gly Arg Phe Gly Ile Gly Phe Asn 
        35                  40                  45


Ser Val Tyr His Ile Thr Asp Val Pro Cys Ile Phe Ser Gly Asp Gln 
    50                  55                  60


Ile Gly Met Leu Asp Pro His Gln Thr Leu Phe Gly Pro His Glu Ser 
65                  70                  75                  80


Gly Gln Cys Trp Asn Leu Lys Asp Asp Ser Lys Glu Ile Ser Glu Leu 
                85                  90                  95


Ser Asp Gln Phe Ala Pro Phe Val Gly Ile Phe Gly Ser Thr Lys Glu 
            100                 105                 110


Thr Phe Ile Asn Gly Asn Phe Pro Gly Thr Phe Phe Arg Phe Pro Leu 
        115                 120                 125


Arg Leu Gln Pro Ser Gln Leu Ser Ser Asn Leu Tyr Asn Lys Gln Lys 
    130                 135                 140


Val Leu Glu Leu Phe Glu Ser Phe Arg Ala Asp Ala Asp Thr Val Leu 
145                 150                 155                 160


Leu Phe Leu Lys Ser Val Gln Asp Val Ser Leu Tyr Val Arg Glu Ala 
                165                 170                 175


Asp Gly Thr Glu Lys Leu Val Phe Arg Val Thr Ser Ser Glu Ser Lys 
            180                 185                 190


Ala Leu Lys His Glu Arg Pro Asn Ser Ile Lys Ile Leu Gly Thr Ala 
        195                 200                 205


Ile Ser Asn Tyr Cys Lys Lys Thr Pro Ser Asn Asn Ile Thr Cys Val 
    210                 215                 220


Thr Tyr His Val Asn Ile Val Leu Glu Glu Glu Ser Thr Lys Asp Ala 
225                 230                 235                 240


Gln Lys Thr Ser Trp Leu Val Cys Asn Ser Val Gly Gly Arg Gly Ile 
                245                 250                 255


Ser Ser Lys Leu Asp Ser Leu Ala Asp Glu Leu Lys Phe Val Pro Ile 
            260                 265                 270


Ile Gly Ile Ala Met Pro Leu Ser Ser Arg Asp Asp Glu Ala Lys Gly 
        275                 280                 285


Ala Thr Ser Asp Phe Ser Gly Lys Ala Phe Cys Phe Leu Pro Leu Pro 
    290                 295                 300


Pro Gly Glu Glu Ser Ser Thr Gly Leu Pro Val His Ile Ser Gly Phe 
305                 310                 315                 320


Phe Gly Leu Thr Asp Asn Arg Arg Ser Ile Lys Trp Arg Glu Leu Asp 
                325                 330                 335


Gln Trp Arg Asp Pro Ala Ala Leu Trp Asn Glu Phe Leu Val Met Asn 
            340                 345                 350


Val Val Pro Lys Ala Tyr Ala Thr Leu Ile Leu Asp Ser Ile Lys Arg 
        355                 360                 365


Leu Glu Met Glu Lys Ser Ser Asp Phe Pro Leu Ser Val Asp Val Ile 
    370                 375                 380


Tyr Lys Leu Trp Pro Glu Ala Ser Lys Val Lys Val His Trp Gln Pro 
385                 390                 395                 400


Val Leu Glu Pro Leu Phe Ser Glu Leu Leu Gln Asn Ala Val Ile Tyr 
                405                 410                 415


Ser Ile Ser Cys Asp Trp Val Arg Leu Glu Gln Val Tyr Phe Ser Glu 
            420                 425                 430


Leu Asp Glu Asn Leu Glu Tyr Thr Lys Thr Val Leu Asn Tyr Leu Gln 
        435                 440                 445


Ser Ser Gly Lys Gln Ile Ala Lys Val Pro Gly Asn Val Asp Ala Ala 
    450                 455                 460


Val Gln Leu Thr Ala Ala Ser Gly Thr Thr Pro Val Arg Lys Val Thr 
465                 470                 475                 480


Pro Ala Trp Val Arg Gln Val Leu Arg Lys Cys Ala His Leu Gly Cys 
                485                 490                 495


Ala Glu Glu Lys Leu His Leu Leu Glu Phe Val Leu Ser Asp Gln Ala 
            500                 505                 510


Tyr Ser Glu Leu Leu Gly Leu Glu Leu Leu Pro Leu Gln Asn Gly Asn 
        515                 520                 525


Phe Val Pro Phe Ser Ser Ser Val Ser Asp Gln Asp Val Ile Tyr Ile 
    530                 535                 540


Thr Ser Ala Glu Tyr Pro Arg Ser Leu Phe Pro Ser Leu Glu Gly Arg 
545                 550                 555                 560


Phe Ile Leu Asp Asn Leu Lys Pro His Leu Val Ala Ala Leu Lys Glu 
                565                 570                 575


Ala Ala Gln Thr Arg Gly Arg Pro Cys Thr Gln Leu Gln Leu Leu Asn 
            580                 585                 590


Pro Glu Arg Phe Ala Arg Leu Ile Lys Glu Val Met Asn Thr Phe Trp 
        595                 600                 605


Pro Gly Arg Glu Leu Ile Val Gln Trp Tyr Pro Phe Asp Glu Asn Arg 
    610                 615                 620


Asn His Pro Ser Val Ser Trp Leu Lys Met Val Trp Lys Asn Leu Tyr 
625                 630                 635                 640


Ile His Phe Ser Glu Asp Leu Thr Leu Phe Asp Glu Met Pro Leu Ile 
                645                 650                 655


Pro Arg Thr Ile Leu Glu Glu Gly Gln Thr Cys Val Glu Leu Ile Arg 
            660                 665                 670


Leu Arg Ile Pro Ser Leu Val Ile Leu Asp Asp Glu Ser Glu Ala Gln 
        675                 680                 685


Leu Pro Glu Phe Leu Ala Asp Ile Val Gln Lys Leu Gly Gly Phe Val 
    690                 695                 700


Leu Lys Lys Leu Asp Ala Ser Ile Gln His Pro Leu Ile Lys Lys Tyr 
705                 710                 715                 720


Ile His Ser Pro Leu Pro Ser Ala Val Leu Gln Ile Met Glu Lys Met 
                725                 730                 735


Pro Leu Gln Lys Leu Cys Asn Gln Ile Thr Ser Leu Leu Pro Thr His 
            740                 745                 750


Lys Asp Ala Leu Arg Lys Phe Leu Ala Ser Leu Thr Asp Ser Ser Glu 
        755                 760                 765


Lys Glu Lys Arg Ile Ile Gln Glu Leu Ala Ile Phe Lys Arg Ile Asn 
    770                 775                 780


His Ser Ser Asp Gln Gly Ile Ser Ser Tyr Thr Lys Leu Lys Gly Cys 
785                 790                 795                 800


Lys Val Leu His His Thr Ala Lys Leu Pro Ala Asp Leu Arg Leu Ser 
                805                 810                 815


Ile Ser Val Ile Asp Ser Ser Asp Glu Ala Thr Ile Arg Leu Ala Asn 
            820                 825                 830


Met Leu Lys Ile Glu Gln Leu Lys Thr Thr Ser Cys Leu Lys Leu Val 
        835                 840                 845


Leu Lys Asp Ile Glu Asn Ala Phe Tyr Ser His Glu Glu Val Thr Gln 
    850                 855                 860


Leu Met Leu Trp Val Leu Glu Asn Leu Ser Ser Leu Lys Asn Glu Asn 
865                 870                 875                 880


Pro Asn Val Leu Glu Trp Leu Thr Pro Leu Lys Phe Ile Gln Ile Ser 
                885                 890                 895


Gln Glu Gln Met Val Ser Ala Gly Glu Leu Phe Asp Pro Asp Ile Glu 
            900                 905                 910


Val Leu Lys Asp Leu Phe Cys Asn Glu Glu Gly Thr Tyr Phe Pro Pro 
        915                 920                 925


Ser Val Phe Thr Ser Pro Asp Ile Leu His Ser Leu Arg Gln Ile Gly 
    930                 935                 940


Leu Lys Asn Glu Ala Ser Leu Lys Glu Lys Asp Val Val Gln Val Ala 
945                 950                 955                 960


Lys Lys Ile Glu Ala Leu Gln Val Gly Ala Cys Pro Asp Gln Asp Val 
                965                 970                 975


Leu Leu Lys Lys Ala Lys Thr Leu Leu Leu Val Leu Asn Lys Asn His 
            980                 985                 990


Thr Leu Leu Gln Ser Ser Glu Gly Lys Met Thr Leu Lys Lys Ile Lys 
        995                 1000                1005


Trp Val Pro Ala Cys Lys Glu Arg Pro Pro Asn Tyr Pro Gly Ser Leu 
    1010                1015                1020


Val Trp Lys Gly Asp Leu Cys Asn Leu Cys Ala Pro Pro Asp Met Cys 
1025                1030                1035                1040


Asp Val Gly His Ala Ile Leu Ile Gly Ser Ser Leu Pro Leu Val Glu 
                1045                1050                1055


Ser Ile His Val Asn Leu Glu Lys Ala Leu Gly Ile Phe Thr Lys Pro 
            1060                1065                1070


Ser Leu Ser Ala Val Leu Lys His Phe Lys Ile Val Val Asp Trp Tyr 
        1075                1080                1085


Ser Ser Lys Thr Phe Ser Asp Glu Asp Tyr Tyr Gln Phe Gln His Ile 
    1090                1095                1100


Leu Leu Glu Ile Tyr Gly Phe Met His Asp His Leu Asn Glu Gly Lys 
1105                1110                1115                1120


Asp Ser Phe Arg Ala Leu Lys Phe Pro Trp Val Trp Thr Gly Lys Lys 
                1125                1130                1135


Phe Cys Pro Leu Ala Gln Ala Val Ile Lys Pro Ile His Asp Leu Asp 
            1140                1145                1150


Leu Gln Pro Tyr Leu His Asn Val Pro Lys Thr Met Ala Lys Phe His 
        1155                1160                1165


Gln Leu Phe Lys Val Cys Gly Ser Ile Glu Glu Leu Thr Ser Asp His 
    1170                1175                1180


Ile Ser Met Val Ile Gln Lys Ile Tyr Leu Lys Ser Asp Gln Asp Leu 
1185                1190                1195                1200


Ser Glu Gln Glu Ser Lys Gln Asn Leu His Leu Met Leu Asn Ile Ile 
                1205                1210                1215


Arg Trp Leu Tyr Ser Asn Gln Ile Pro Ala Ser Pro Asn Thr Pro Val 
            1220                1225                1230


Pro Ile His His Ser Lys Asn Pro Ser Lys Leu Ile Met Lys Pro Ile 
        1235                1240                1245


His Glu Cys Cys Tyr Cys Asp Ile Lys Val Asp Asp Leu Asn Asp Leu 
    1250                1255                1260


Leu Glu Asp Ser Val Glu Pro Ile Ile Leu Val His Glu Asp Ile Pro 
1265                1270                1275                1280


Met Lys Thr Ala Glu Trp Leu Lys Val Pro Cys Leu Ser Thr Arg Leu 
                1285                1290                1295


Ile Asn Pro Glu Asn Met Gly Phe Glu Gln Ser Gly Gln Arg Glu Pro 
            1300                1305                1310


Leu Thr Val Arg Ile Lys Asn Ile Leu Glu Glu Tyr Pro Ser Val Ser 
        1315                1320                1325


Asp Ile Phe Lys Glu Leu Leu Gln Asn Ala Asp Asp Ala Asn Ala Thr 
    1330                1335                1340


Glu Cys Ser Phe Leu Ile Asp Met Arg Arg Asn Met Asp Ile Arg Glu 
1345                1350                1355                1360


Asn Leu Leu Asp Pro Gly Met Ala Ala Cys His Gly Pro Ala Leu Trp 
                1365                1370                1375


Ser Phe Asn Asn Ser Gln Phe Ser Asp Ser Asp Phe Val Asn Ile Thr 
            1380                1385                1390


Arg Leu Gly Glu Ser Leu Lys Arg Gly Glu Val Asp Lys Val Gly Lys 
        1395                1400                1405


Phe Gly Leu Gly Phe Asn Ser Val Tyr His Ile Thr Asp Ile Pro Ile 
    1410                1415                1420


Ile Met Ser Arg Glu Phe Met Ile Met Phe Asp Pro Asn Ile Asn His 
1425                1430                1435                1440


Ile Ser Lys His Ile Lys Asp Lys Ser Asn Pro Gly Ile Lys Ile Asn 
                1445                1450                1455


Trp Ser Lys Gln Gln Lys Arg Leu Arg Lys Phe Pro Asn Gln Phe Lys 
            1460                1465                1470


Pro Phe Ile Asp Val Phe Gly Cys Gln Leu Pro Leu Thr Val Glu Ala 
        1475                1480                1485


Pro Tyr Ser Tyr Asn Gly Thr Leu Phe Arg Leu Ser Phe Arg Thr Gln 
    1490                1495                1500


Gln Glu Ala Lys Val Ser Glu Val Ser Ser Thr Cys Tyr Asn Thr Ala 
1505                1510                1515                1520


Asp Ile Tyr Ser Leu Val Asp Glu Phe Ser Leu Cys Gly His Arg Leu 
                1525                1530                1535


Ile Ile Phe Thr Gln Ser Val Lys Ser Met Tyr Leu Lys Tyr Leu Lys 
            1540                1545                1550


Ile Glu Glu Thr Asn Pro Ser Leu Ala Gln Asp Thr Val Ile Ile Lys 
        1555                1560                1565


Lys Lys Ser Cys Ser Ser Lys Ala Leu Asn Thr Pro Val Leu Ser Val 
    1570                1575                1580


Leu Lys Glu Ala Ala Lys Leu Met Lys Thr Cys Ser Ser Ser Asn Lys 
1585                1590                1595                1600


Lys Leu Pro Ser Asp Glu Pro Lys Ser Ser Cys Ile Leu Gln Ile Thr 
                1605                1610                1615


Val Glu Glu Phe His His Val Phe Arg Arg Ile Ala Asp Leu Gln Ser 
            1620                1625                1630


Pro Leu Phe Arg Gly Pro Asp Asp Asp Pro Ala Ala Leu Phe Glu Met 
        1635                1640                1645


Ala Lys Ser Gly Gln Ser Lys Lys Pro Ser Asp Glu Leu Ser Gln Lys 
    1650                1655                1660


Thr Val Glu Cys Thr Thr Trp Leu Leu Cys Thr Cys Met Asp Thr Gly 
1665                1670                1675                1680


Glu Ala Leu Lys Phe Ser Leu Ser Glu Ser Gly Arg Arg Leu Gly Leu 
                1685                1690                1695


Val Pro Cys Gly Ala Val Gly Val Gln Leu Ser Glu Ile Gln Asp Gln 
            1700                1705                1710


Lys Trp Thr Val Lys Pro His Ile Gly Glu Val Phe Cys Tyr Leu Pro 
        1715                1720                1725


Leu Arg Ile Lys Thr Gly Leu Pro Val His Ile Asn Gly Cys Phe Ala 
    1730                1735                1740


Val Thr Ser Asn Arg Lys Glu Ile Trp Lys Thr Asp Thr Lys Gly Arg 
1745                1750                1755                1760


Trp Asn Thr Thr Phe Met Arg His Val Ile Val Lys Ala Tyr Leu Gln 
                1765                1770                1775


Val Leu Ser Val Leu Arg Asp Leu Ala Thr Ser Gly Glu Leu Met Asp 
            1780                1785                1790


Tyr Thr Tyr Tyr Ala Val Trp Pro Asp Pro Asp Leu Val His Asp Asp 
        1795                1800                1805


Phe Ser Val Ile Cys Gln Gly Phe Tyr Glu Asp Ile Ala His Gly Lys 
    1810                1815                1820


Gly Lys Glu Leu Thr Lys Val Phe Ser Asp Gly Ser Thr Trp Val Ser 
1825                1830                1835                1840


Met Lys Asn Val Arg Phe Leu Asp Asp Ser Ile Leu Lys Arg Arg Asp 
                1845                1850                1855


Val Gly Ser Ala Ala Phe Lys Ile Phe Leu Lys Tyr Leu Lys Lys Thr 
            1860                1865                1870


Gly Ser Lys Asn Leu Cys Ala Val Glu Leu Pro Ser Ser Val Lys Leu 
        1875                1880                1885


Gly Phe Glu Glu Ala Gly Cys Lys Gln Ile Leu Leu Glu Asn Thr Phe 
    1890                1895                1900


Ser Glu Lys Gln Phe Phe Ser Glu Val Phe Phe Pro Asn Ile Gln Glu 
1905                1910                1915                1920


Ile Glu Ala Glu Leu Arg Asp Pro Leu Met Ile Phe Val Leu Asn Glu 
                1925                1930                1935


Lys Val Asp Glu Phe Ser Gly Val Leu Arg Val Thr Pro Cys Ile Pro 
            1940                1945                1950


Cys Ser Leu Glu Gly His Pro Leu Val Leu Pro Ser Arg Leu Ile His 
        1955                1960                1965


Pro Glu Gly Arg Val Ala Lys Leu Phe Asp Ile Lys Asp Gly Arg Phe 
    1970                1975                1980


Pro Tyr Gly Ser Thr Gln Asp Tyr Leu Asn Pro Ile Ile Leu Ile Lys 
1985                1990                1995                2000


Leu Val Gln Leu Gly Met Ala Lys Asp Asp Ile Leu Trp Asp Asp Met 
                2005                2010                2015


Leu Glu Arg Ala Val Ser Val Ala Glu Ile Asn Lys Ser Asp His Val 
            2020                2025                2030


Ala Ala Cys Leu Arg Ser Ser Ile Leu Leu Ser Leu Ile Asp Glu Lys 
        2035                2040                2045


Leu Lys Ile Arg Asp Pro Arg Ala Lys Asp Phe Ala Ala Lys Tyr Gln 
    2050                2055                2060


Thr Ile Arg Phe Leu Pro Phe Leu Thr Lys Pro Ala Gly Phe Ser Leu 
2065                2070                2075                2080


Asp Trp Lys Gly Asn Ser Phe Lys Pro Glu Thr Met Phe Ala Ala Thr 
                2085                2090                2095


Asp Leu Tyr Thr Ala Glu His Gln Asp Ile Val Cys Leu Leu Gln Pro 
            2100                2105                2110


Ile Leu Asn Glu Asn Ser His Ser Phe Arg Gly Cys Gly Ser Val Ser 
        2115                2120                2125


Leu Ala Val Lys Glu Phe Leu Gly Leu Leu Lys Lys Pro Thr Val Asp 
    2130                2135                2140


Leu Val Ile Asn Gln Leu Lys Glu Val Ala Lys Ser Val Asp Asp Gly 
2145                2150                2155                2160


Ile Thr Leu Tyr Gln Glu Asn Ile Thr Asn Ala Cys Tyr Lys Tyr Leu 
                2165                2170                2175


His Glu Ala Leu Met Gln Asn Glu Ile Thr Lys Met Ser Ile Ile Asp 
            2180                2185                2190


Lys Leu Lys Pro Phe Ser Phe Ile Leu Val Glu Asn Ala Tyr Val Asp 
        2195                2200                2205


Ser Glu Lys Val Ser Phe His Leu Asn Phe Glu Ala Ala Pro Tyr Leu 
    2210                2215                2220


Tyr Gln Leu Pro Asn Lys Tyr Lys Asn Asn Phe Arg Glu Leu Phe Glu 
2225                2230                2235                2240


Thr Val Gly Val Arg Gln Ser Cys Thr Val Glu Asp Phe Ala Leu Val 
                2245                2250                2255


Leu Glu Ser Ile Asp Gln Glu Arg Gly Thr Lys Gln Ile Thr Glu Glu 
            2260                2265                2270


Asn Phe Gln Leu Cys Arg Arg Ile Ile Ser Glu Gly Ile Trp Ser Leu 
        2275                2280                2285


Ile 



<210>  8238
<211>  1188
<212>  DNA
<213>  Homo sapiens

<400>  8238
tttaaaggaa gctgcccaaa cccgagcaca acaacaactc tggggatatt caggaagacc     60

atgtactcag ctgcagcttc taaatccaga acgatttgca cgtcttatca aggaagtaat    120

gaatacattc tggcctggca gagaattgat tgttcaatgg tatccatttg atgaaaacag    180

aaatcaccca tctgtttcat ggcttaagat ggtttggaaa aatctttata tacatttttc    240

agaggatttg actttatttg atgagatgcc acttatcccc agaactatac tagaggaagg    300

tcagacatgt gtggaactca ttagactcag gattccatcg ttagtcattt tagacgatga    360

atctgaagca cagcttccag aatttttagc agacattgta caaaaacttg gagggtttgt    420

ccttaaaaaa ttagatgcat ctatacaaca tccgcttatt aaaaaatata ttcattcacc    480

attaccaagt gctgttttgc agataatgga gaagatgcca ttgcagaaat tgtgtaatca    540

aataacttcg ctacttccaa cacacaaaga tgccctgagg aagttcttgg ctagtttaac    600

cgatagcagt gagaaagaga aaagaattat tcaagaattg gcaatattca agcgcattaa    660

ccattcttct gatcagggaa tttcctctta tacaaaattg aaaggttgta aagtcttaca    720

ccatactgcc aaactcccag cagatctgcg actttctatt tcagtaatag acagtagtga    780

tgaagctact attcgtctgg caaacatgtt gaaaatagaa cagttaaaga ccactagctg    840

cttaaagctt gttttaaaag atattgaaaa tgcattttat tcacatgaag aggtaacaca    900

gcttatgtta tgggtccttg agaatctatc ttctcttaaa aatgagaatc caaatgtgct    960

tgagtggtta acaccattaa aattcatcca gatatcacag gaacagatgg tatcagctgg   1020

tgaactcttt gaccctgata tagaagtact aaaggatctc ttttgtaatg aagaaggaac   1080

ctatttccca ccctcagttt ttacctcacc agatattctt cactccttaa gacagattgg   1140

tttaaaaaac gaagccagtc tcaaagaaaa ggatgttgtg caagtggc                1188


<210>  8239
<211>  355
<212>  PRT
<213>  Homo sapiens

<400>  8239

Met Asn Thr Phe Trp Pro Gly Arg Glu Leu Ile Val Gln Trp Tyr Pro 
1               5                   10                  15


Phe Asp Glu Asn Arg Asn His Pro Ser Val Ser Trp Leu Lys Met Val 
            20                  25                  30


Trp Lys Asn Leu Tyr Ile His Phe Ser Glu Asp Leu Thr Leu Phe Asp 
        35                  40                  45


Glu Met Pro Leu Ile Pro Arg Thr Ile Leu Glu Glu Gly Gln Thr Cys 
    50                  55                  60


Val Glu Leu Ile Arg Leu Arg Ile Pro Ser Leu Val Ile Leu Asp Asp 
65                  70                  75                  80


Glu Ser Glu Ala Gln Leu Pro Glu Phe Leu Ala Asp Ile Val Gln Lys 
                85                  90                  95


Leu Gly Gly Phe Val Leu Lys Lys Leu Asp Ala Ser Ile Gln His Pro 
            100                 105                 110


Leu Ile Lys Lys Tyr Ile His Ser Pro Leu Pro Ser Ala Val Leu Gln 
        115                 120                 125


Ile Met Glu Lys Met Pro Leu Gln Lys Leu Cys Asn Gln Ile Thr Ser 
    130                 135                 140


Leu Leu Pro Thr His Lys Asp Ala Leu Arg Lys Phe Leu Ala Ser Leu 
145                 150                 155                 160


Thr Asp Ser Ser Glu Lys Glu Lys Arg Ile Ile Gln Glu Leu Ala Ile 
                165                 170                 175


Phe Lys Arg Ile Asn His Ser Ser Asp Gln Gly Ile Ser Ser Tyr Thr 
            180                 185                 190


Lys Leu Lys Gly Cys Lys Val Leu His His Thr Ala Lys Leu Pro Ala 
        195                 200                 205


Asp Leu Arg Leu Ser Ile Ser Val Ile Asp Ser Ser Asp Glu Ala Thr 
    210                 215                 220


Ile Arg Leu Ala Asn Met Leu Lys Ile Glu Gln Leu Lys Thr Thr Ser 
225                 230                 235                 240


Cys Leu Lys Leu Val Leu Lys Asp Ile Glu Asn Ala Phe Tyr Ser His 
                245                 250                 255


Glu Glu Val Thr Gln Leu Met Leu Trp Val Leu Glu Asn Leu Ser Ser 
            260                 265                 270


Leu Lys Asn Glu Asn Pro Asn Val Leu Glu Trp Leu Thr Pro Leu Lys 
        275                 280                 285


Phe Ile Gln Ile Ser Gln Glu Gln Met Val Ser Ala Gly Glu Leu Phe 
    290                 295                 300


Asp Pro Asp Ile Glu Val Leu Lys Asp Leu Phe Cys Asn Glu Glu Gly 
305                 310                 315                 320


Thr Tyr Phe Pro Pro Ser Val Phe Thr Ser Pro Asp Ile Leu His Ser 
                325                 330                 335


Leu Arg Gln Ile Gly Leu Lys Asn Glu Ala Ser Leu Lys Glu Lys Asp 
            340                 345                 350


Val Val Gln 
        355


<210>  8240
<211>  789
<212>  DNA
<213>  Homo sapiens

<400>  8240
ggagagagct ggaccagtgg agagacccgg cagccttatg gaatgagttt cttgtcatga     60

atgttgtccc caaagcttat gctactctga tcttagattc aataaaacgt ctggagatgg    120

aaaagagctc tgatttcccc ttgtcagttg atgttatcta taagctttgg ccggaggcga    180

gcaaagtcaa ggtgcactgg caaccggtgt tagagcctct attcagcgag ctgttgcaga    240

atgcagtgat ttattcaatt agctgtgact gggtcaggtt ggagcaggtg tacttctcag    300

aacttgatga aaatttagaa tacacaaaaa ctgtgctcaa ctacctccag agctcaggga    360

agcagattgc caaggtacca gggaatgtgg atgctgctgt tcagctcaca gctgcctctg    420

gcacaacacc tgtgaggaag gtgacgcccg cgtgggtgcg gcaggtgctg cggaagtgtg    480

cacacctggg ctgtgctgaa gaaaagcttc accttctaga atttgtgctt tctgaccaag    540

cctacagtga gctgcttggg ctggagctgc tccctttaca aaatggcaat tttgtcccct    600

tctcctcatc tgtatcagac caagatgtca tttatattac ctcagcagaa tatccaaggt    660

cccttttccc aagtcttgaa ggaagattta ttttggataa cttgaaacct caccttgtgg    720

ctgctttaaa ggaagctgcc caaacccgag gtattatagt ttagtattct tttaaataaa    780

cttctatat                                                            789


<210>  8241
<211>  235
<212>  PRT
<213>  Homo sapiens

<400>  8241

Met Asn Val Val Pro Lys Ala Tyr Ala Thr Leu Ile Leu Asp Ser Ile 
1               5                   10                  15


Lys Arg Leu Glu Met Glu Lys Ser Ser Asp Phe Pro Leu Ser Val Asp 
            20                  25                  30


Val Ile Tyr Lys Leu Trp Pro Glu Ala Ser Lys Val Lys Val His Trp 
        35                  40                  45


Gln Pro Val Leu Glu Pro Leu Phe Ser Glu Leu Leu Gln Asn Ala Val 
    50                  55                  60


Ile Tyr Ser Ile Ser Cys Asp Trp Val Arg Leu Glu Gln Val Tyr Phe 
65                  70                  75                  80


Ser Glu Leu Asp Glu Asn Leu Glu Tyr Thr Lys Thr Val Leu Asn Tyr 
                85                  90                  95


Leu Gln Ser Ser Gly Lys Gln Ile Ala Lys Val Pro Gly Asn Val Asp 
            100                 105                 110


Ala Ala Val Gln Leu Thr Ala Ala Ser Gly Thr Thr Pro Val Arg Lys 
        115                 120                 125


Val Thr Pro Ala Trp Val Arg Gln Val Leu Arg Lys Cys Ala His Leu 
    130                 135                 140


Gly Cys Ala Glu Glu Lys Leu His Leu Leu Glu Phe Val Leu Ser Asp 
145                 150                 155                 160


Gln Ala Tyr Ser Glu Leu Leu Gly Leu Glu Leu Leu Pro Leu Gln Asn 
                165                 170                 175


Gly Asn Phe Val Pro Phe Ser Ser Ser Val Ser Asp Gln Asp Val Ile 
            180                 185                 190


Tyr Ile Thr Ser Ala Glu Tyr Pro Arg Ser Leu Phe Pro Ser Leu Glu 
        195                 200                 205


Gly Arg Phe Ile Leu Asp Asn Leu Lys Pro His Leu Val Ala Ala Leu 
    210                 215                 220


Lys Glu Ala Ala Gln Thr Arg Gly Ile Ile Val 
225                 230                 235


<210>  8242
<211>  289
<212>  DNA
<213>  Homo sapiens

<400>  8242
gtaaaccttc aatcaaaagg cttaaaaggg ggaggtcgat ttggtcagac aacgccacca     60

cttgttgatt ttctcaagga cattttgaga agatatccag aaggaggaca gattcttaag    120

gaattaattc agaatgcaga agatgctggg gcgacagaag ttaaattttt atatgatgaa    180

actcaatacg gaacagagac tctttggtca aaagatatgg cgccatatca ggatgttcct    240

tgtatcttta gtggtgacca aatcgggatg ctagatcctc atcaaacac                289


<210>  8243
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  8243

Met Gln Lys Met Leu Gly Arg Gln Lys Leu Asn Phe Tyr Met Met Lys 
1               5                   10                  15


Leu Asn Thr Glu Gln Arg Leu Phe Gly Gln Lys Ile Trp Arg His Ile 
            20                  25                  30


Arg Met Phe Leu Val Ser Leu Val Val Thr Lys Ser Gly Cys 
        35                  40                  45


<210>  8244
<211>  1762
<212>  DNA
<213>  Homo sapiens

<400>  8244
aagtgcggga tctggatggc tgctttgggt gcttccagga gcaggctgcg tgcaggcctg     60

gcagcagtgc ccaggttggg gtgcctgcaa cccctgaagc tccagagggc atgttacagt    120

gttcttttag ctctgccgtc tgtggacagt ggctgaaatg cagtggcatg atcttagctc    180

actacaacct ctgcctcctg ggttcaagag attctcacgt ctcagccacc taagtacatg    240

ggattacagt atgaaaacgt cacactatct ttgctcagat ctgtgccaga atcaactttt    300

aatgctatat ttaatagaga aaatgatgag gaagtttctg caaagaagga atgacagaat    360

tagaatataa caattttgca atgcctaatg aattactgga tctaggcaac attcatcaat    420

ggctgctaat attatagaaa gaaagaaaac cagacattat atatctcatg ctagaagtgc    480

acaagaccac ttaaatagtc ttcccctcca ccaaaatcca acctgagtct gatcatacct    540

tgaaatcaat ctaccatgtt gagaaaatac tcaagggaag gccaggagtg gagattcaca    600

cctgtaatcc cagcactttg ggaggccaag gtgggtggat ggattacttg aggtcaggag    660

ctcaagaaca gcctggccaa catcacgaaa ccccagtctc taataaaaat acaaaaatta    720

ggtgggcctg gtggtgtgcg cctgtagtcc cagctacttg ggaggctgag gcacaagaat    780

cacttgaacc taggaggcaa aggttgcagt gagtcaagct cgcactactg cactccagcc    840

tgggcgacag agtgagagac tctgtctcaa aaaaaagaaa aaaaaaaaaa aggccgggtg    900

tggtggctca cacctgtaat cccagcactt tgggaggcca tggcaggcgg atcacctgag    960

gtcaggagtt tgagaccagc ctggcaacat ggtgaaaccc cgtctctcct aaaaatacaa   1020

aaattagctg ggcatggtgg cgcatgcctg tagtcccagc ttctcaggag gctgaggaag   1080

gagaagtgct tgaacccagg aggtggaggt tgcagtgagc tgagattgtg ccctccagcc   1140

tggcaacaga gtgagactcc atctcaaaaa aacaaaaaac aaaaaacaag ggaagaagta   1200

acatcataca tgagaccttg gagatgcaat cagaaaactc tagaatgtag aaaactgtat   1260

agcagggccg ggtgcggtgg ctcacgcctg taagcccagc actttggcag gccgaggcag   1320

gcggatcatg aggtcaagag atcgagagca tcctggccaa catggtgaaa ccccgtctct   1380

actaaaaata caaaaattag ctgggcgtgg tggcaagtgc ctgtagtccc agctactcag   1440

gaggctgagg caggagaatc gcttgaatct gggaggtgga ggttgcagtg agccaagatc   1500

atgccactgc actgcagcct ggcaacagag cgagactccg tctcaaaaaa aaaaaaaaca   1560

cacacaacaa caactgtata ggacaagtaa attagttttt catcaacaac aatgatggag   1620

agtggtgtat gaatcagaga gagaggagga gagagaaggg gaacagaggg aaggcaagga   1680

gaaaggagag gagaggacta agagacatca aaaccaacca caatgtatgg accttatttg   1740

gcttccaatc taaacacact gt                                            1762


<210>  8245
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8245

Met Gln Trp His Asp Leu Ser Ser Leu Gln Pro Leu Pro Pro Gly Phe 
1               5                   10                  15


Lys Arg Phe Ser Arg Leu Ser His Leu Ser Thr Trp Asp Tyr Ser Met 
            20                  25                  30


Lys Thr Ser His Tyr Leu Cys Ser Asp Leu Cys Gln Asn Gln Leu Leu 
        35                  40                  45


Met Leu Tyr Leu Ile Glu Lys Met Met Arg Lys Phe Leu Gln Arg Arg 
    50                  55                  60


Asn Asp Arg Ile Arg Ile 
65                  70


<210>  8246
<211>  321
<212>  DNA
<213>  Homo sapiens

<400>  8246
gccactgtga cagccttttt tgggtaccca cattcagtgg atcccaagct cttgtgtggc     60

atctaagatg aatgagatag cccagacact tgaaggatgg tgaaggtgga gaattgtgtt    120

aggcaatggg aaatgcctct cagcaaagag gggagccgga gaggggacag gacagcaata    180

cctaatgagc aattaaagtg acttactgag agtgaaggct tcttgcaggt cacagcagcc    240

atatgtcaca tcagacataa ggcactgaac agaagcaatt caacggaatc atgtcatcca    300

tcaggcaaaa tacatgcaga g                                              321


<210>  8247
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  8247

Met Val Lys Val Glu Asn Cys Val Arg Gln Trp Glu Met Pro Leu Ser 
1               5                   10                  15


Lys Glu Gly Ser Arg Arg Gly Asp Arg Thr Ala Ile Pro Asn Glu Gln 
            20                  25                  30


Leu Lys 



<210>  8248
<211>  1329
<212>  DNA
<213>  Homo sapiens

<400>  8248
gcagtgcgca ggcgcagtcc cggctcctgg cggcgtgttc ctcttttcct cggttcccag     60

tgttctggca ggtaaggaac gccggctctt cgcctctcag cgcggcttgt cctttgttcc    120

ggacgcccgc tcctcagccc tgcggctcct ggggtcgctg ctgcatcccg cacgcctcca    180

ccggctgcag acccatggcc gagcgcgggg aactcgactt gaccggcgcc aaacagaaca    240

caggagtgtg gctagtcaag gttcctaaat atttgtcaca gcaatgggct aaagcctctg    300

gaagaggtga agttgggaaa ctgcggattg ccaagactca aggaaggact gaggtgtcat    360

ttactttgaa tgaggatctt gcaaatattc atgatattgg tggaaaacca gcttcagtca    420

gtgctcctag agaacatcca tttgtcttgc aaagtgttgg aggacagaca ttaacagtat    480

ttactgagag ctcatcagat aagctgtcat tggaaggaat agtggtacaa agagctgaat    540

gccgaccagc tgccagtgaa aactacatgc gattaaaaag attgcaaata gaagagtctt    600

ccaaaccagt gaggctatca caacagctgg acaaagttgt aacaaccaat tacaaacctg    660

ttgctaatca tcaatacaat atcgaatatg aaaggaaaaa gaaagaagac ggaaagcgag    720

ctcgagctga taaacaacat gttttagaca tgctattttc agcctttgag aaacatcaat    780

actataatct taaggacttg gtggacatca caaagcaacc tgtggtgtac ctgaaggaaa    840

tcttaaaaga aattggtgtt cagaatgtaa aagggatcca caaaaacaca tgggagctga    900

agccagagta cagacactat caaggagaag aaaagagtga ctaagaagac tcctagccag    960

catgctagtg aaacgactag cagcgatgct atgcaaaagg cgctgatact ggaaggcttg   1020

aacaccgtat gttaataggg gttaagtgac agtactttga tttctctcgg taaatttttt   1080

aaacctgtaa ttcttgtaaa gtttcttaac tgtttttttg aggagaaaga acagatttat   1140

ttatagactt aacttgtatt aaaccagatt attcacagta ggaatagggg ttggaggatt   1200

aagagggttt ttcttaaata ttagctttta atgtgtacaa ttaggaaatt tttttaagtg   1260

aggactctct acccttgccg tatctaagga gctgaggtaa tacagatcca aggagaattg   1320

tatagcaag                                                           1329


<210>  8249
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  8249

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Asp Lys Leu Ser Leu Glu Gly Ile Val Val Gln 
            100                 105                 110


Arg Ala Glu Cys Arg Pro Ala Ala Ser Glu Asn Tyr Met Arg Leu Lys 
        115                 120                 125


Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg Leu Ser Gln Gln 
    130                 135                 140


Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val Ala Asn His Gln 
145                 150                 155                 160


Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala 
                165                 170                 175


Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu 
            180                 185                 190


Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln 
        195                 200                 205


Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn 
    210                 215                 220


Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg 
225                 230                 235                 240


His Tyr Gln Gly Glu Glu Lys Ser Asp 
                245


<210>  8250
<211>  1402
<212>  DNA
<213>  Homo sapiens

<400>  8250
gcagtgcgca ggcgcagtcc cggctcctgg cggcgtgttc ctcttttcct cggttcccag     60

tgttctggca ggtaaggaac gccggctctt cgcctctcag cgcggcttgt cctttgttcc    120

ggacgcccgc tcctcagccc tgcggctcct ggggtcgctg ctgcatcccg cacgcctcca    180

ccggctgcag acccatggcc gagcgcgggg aactcgactt gaccggcgcc aaacagaaca    240

caggagtgtg gctagtcaag gttcctaaat atttgtcaca gcaatgggct aaagcctctg    300

gaagaggtga agttgggaaa ctgcggattg ccaagactca aggaaggact gaggtgtcat    360

ttactttgaa tgaggatctt gcaaatattc atgatattgg tggaaaacca gcttcagtca    420

gtgctcctag agaacatcca tttgtcttgc aaagtgttgg aggacagaca ttaacagtat    480

ttactgagag ctcatcagat aagctgtcat tggaaggaat agtggtacaa agagctgaat    540

gccgaccagc tgccagtgaa aactacatgc gattaaaaag attgcaaata gaagagtctt    600

ccaaaccagt gaggctatca caacagctgg acaaagttgt aacaaccaat tacaaacctg    660

ttgctaatca tcaatacaat atcgaatatg aaaggaaaaa gaaagaagac ggaaagcgag    720

ctcgagctga taaacaacat gttttagaca tgctattttc agcctttgag aaacatcaat    780

actataatct taaggacttg gtggacatca caaagcaacc tgtggtgtac ctgaaggaaa    840

tcttaaaaga aattggtgtt cagaatgtaa aagggatcca caaaaacaca tgggagctga    900

agccagagta cagacactat caaggagaag aaaagagtga ctaagaagac tcctagccag    960

catgctagtg aaacgactag cagcgatgct atgcaaaagg cgctgatact ggaaggcttg   1020

aacaccgtat gttaataggg gttaagtgac agtactttga tttctctcgg taaatttttt   1080

aaacctgtaa ttcttgtaaa gtttcttaac tgtttttttg aggagaaaga acagatttat   1140

ttatagactt aacttgtatt aaaccagatt attcacagta ggaatagggg ttggaggatt   1200

aagagggttt ttcttaaata ttagctttta atgtgtacaa ttaggaaatt tttttaagtg   1260

aggactctct acccttgccg tatctaagga gctgaggtaa tacagatcca aggagaattg   1320

tatagcaaga aaaaaacagt caactacaga aactcttaaa aggaataaaa acccaaagtt   1380

ccttattttg aaattgtcaa ag                                            1402


<210>  8251
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  8251

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Asp Lys Leu Ser Leu Glu Gly Ile Val Val Gln 
            100                 105                 110


Arg Ala Glu Cys Arg Pro Ala Ala Ser Glu Asn Tyr Met Arg Leu Lys 
        115                 120                 125


Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg Leu Ser Gln Gln 
    130                 135                 140


Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val Ala Asn His Gln 
145                 150                 155                 160


Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala 
                165                 170                 175


Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu 
            180                 185                 190


Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln 
        195                 200                 205


Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn 
    210                 215                 220


Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg 
225                 230                 235                 240


His Tyr Gln Gly Glu Glu Lys Ser Asp 
                245


<210>  8252
<211>  1485
<212>  DNA
<213>  Homo sapiens

<400>  8252
gcagtgcgca ggcgcagtcc cggctcctgg cggcgtgttc ctcttttcct cggttcccag     60

tgttctggca ggtaaggaac gccggctctt cgcctctcag cgcggcttgt cctttgttcc    120

ggacgcccgc tcctcagccc tgcggctcct ggggtcgctg ctgcatcccg cacgcctcca    180

ccggctgcag acccatggcc gagcgcgggg aactcgactt gaccggcgcc aaacagaaca    240

caggagtgtg gctagtcaag gttcctaaat atttgtcaca gcaatgggct aaagcctctg    300

gaagaggtga agttgggaaa ctgcggattg ccaagactca aggaaggact gaggtgtcat    360

ttactttgaa tgaggatctt gcaaatattc atgatattgg tggaaaacca gcttcagtca    420

gtgctcctag agaacatcca tttgtcttgc aaagtgttgg aggacagaca ttaacagtat    480

ttactgagag ctcatcagat aagctgtcat tggaaggaat agtggtacaa agagctgaat    540

gccgaccagc tgccagtgaa aactacatgc gattaaaaag attgcaaata gaagagtctt    600

ccaaaccagt gaggctatca caacagctgg acaaagttgt aacaaccaat tacaaacctg    660

ttgctaatca tcaatacaat atcgaatatg aaaggaaaaa gaaagaagac ggaaagcgag    720

ctcgagctga taaacaacat gttttagaca tgctattttc agcctttgag aaacatcaat    780

actataatct taaggacttg gtggacatca caaagcaacc tgtggtgtac ctgaaggaaa    840

tcttaaaaga aattggtgtt cagaatgtaa aagggatcca caaaaacaca tgggagctga    900

agccagagta cagacactat caaggagaag aaaagagtga ctaagaagac tcctagccag    960

catgctagtg aaacgactag cagcgatgct atgcaaaagg cgctgatact ggaaggcttg   1020

aacaccgtat gttaataggg gttaagtgac agtactttga tttctctcgg taaatttttt   1080

aaacctgtaa ttcttgtaaa gtttcttaac tgtttttttg aggagaaaga acagatttat   1140

ttatagactt aacttgtatt aaaccagatt attcacagta ggaatagggg ttggaggatt   1200

aagagggttt ttcttaaata ttagctttta atgtgtacaa ttaggaaatt tttttaagtg   1260

aggactctct acccttgccg tatctaagga gctgaggtaa tacagatcca aggagaattg   1320

tatagcaaga aaaaaacagt caactacaga aactcttaaa aggaataaaa acccaaagtt   1380

ccttattttg aaattgtcaa agaacaaagc ggtgtttttc ttttaaacag gtgatcacgt   1440

ttcgtgttca tactcaacgt taataaaagg agagagtttg tagtg                   1485


<210>  8253
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  8253

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Asp Lys Leu Ser Leu Glu Gly Ile Val Val Gln 
            100                 105                 110


Arg Ala Glu Cys Arg Pro Ala Ala Ser Glu Asn Tyr Met Arg Leu Lys 
        115                 120                 125


Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg Leu Ser Gln Gln 
    130                 135                 140


Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val Ala Asn His Gln 
145                 150                 155                 160


Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala 
                165                 170                 175


Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu 
            180                 185                 190


Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln 
        195                 200                 205


Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn 
    210                 215                 220


Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg 
225                 230                 235                 240


His Tyr Gln Gly Glu Glu Lys Ser Asp 
                245


<210>  8254
<211>  2291
<212>  DNA
<213>  Homo sapiens

<400>  8254
gcagtgcgca ggcgcagtcc cggctcctgg cggcgtgttc ctcttttcct cggttcccag     60

tgttctggca ggtaaggaac gccggctctt cgcctctcag cgcggcttgt cctttgttcc    120

ggacgcccgc tcctcagccc tgcggctcct ggggtcgctg ctgcatcccg cacgcctcca    180

ccggctgcag acccatggcc gagcgcgggg aactcgactt gaccggcgcc aaacagaaca    240

caggagtgtg gctagtcaag gttcctaaat atttgtcaca gcaatgggct aaagcctctg    300

gaagaggtga agttgggaaa ctgcggattg ccaagactca aggaaggact gaggtgtcat    360

ttactttgaa tgaggatctt gcaaatattc atgatattgg tggaaaacca gcttcagtca    420

gtgctcctag agaacatcca tttgtcttgc aaagtgttgg aggacagaca ttaacagtat    480

ttactgagag ctcatcagat aagctgtcat tggaaggaat agtggtacaa agagctgaat    540

gccgaccagc tgccagtgaa aactacatgc gattaaaaag attgcaaata gaagagtctt    600

ccaaaccagt gaggctatca caacagctgg acaaagttgt aacaaccaat tacaaacctg    660

ttgctaatca tcaatacaat atcgaatatg aaaggaaaaa gaaagaagac ggaaagcgag    720

ctcgagctga taaacaacat gttttagaca tgctattttc agcctttgag aaacatcaat    780

actataatct taaggacttg gtggacatca caaagcaacc tgtggtgtac ctgaaggaaa    840

tcttaaaaga aattggtgtt cagaatgtaa aagggatcca caaaaacaca tgggagctga    900

agccagagta cagacactat caaggagaag aaaagagtga ctaagaagac tcctagccag    960

catgctagtg aaacgactag cagcgatgct atgcaaaagg cgctgatact ggaaggcttg   1020

aacaccgtat gttaataggg gttaagtgac agtactttga tttctctcgg taaatttttt   1080

aaacctgtaa ttcttgtaaa gtttcttaac tgtttttttg aggagaaaga acagatttat   1140

ttatagactt aacttgtatt aaaccagatt attcacagta ggaatagggg ttggaggatt   1200

aagagggttt ttcttaaata ttagctttta atgtgtacaa ttaggaaatt tttttaagtg   1260

aggactctct acccttgccg tatctaagga gctgaggtaa tacagatcca aggagaattg   1320

tatagcaaga aaaaaacagt caactacaga aactcttaaa aggaataaaa acccaaagtt   1380

ccttattttg aaattgtcaa agaacaaagc ggtgtttttc ttttaaacag gtgatcacgt   1440

ttcgtgttca tactcaacgt taataaaagg agagagtttg tagtgaaatg gcagtgttca   1500

tcattggctt attttaccgt agtgatgctg agatgagaaa tgtgcaggat catggtcagt   1560

tgatgtttct tttatttgct tttaagataa ttagaaatta aatatctttc caaaatttga   1620

agatatgtct cccccagtca gattataagc ttctcaaaac tggcttgccc ccagaatttt   1680

actgcttacc cagcagacat gtattgacca tcacatggca aatgatatca gcaaatcaaa   1740

agatgggcgt aggggtccag ccgagacaga aaacgttagt ttcaattcct ggggcattaa   1800

aatgttgctt ttctctttct ctttaattaa tttttaaatg aaaacaatac atgtatatgt   1860

tagttttttc tagcacaaca caatattata tattaagcga tccaaaatca tactgtcaag   1920

accatcaaac aaaacaaaga agcttaagtg aactaagcac agggaaaagt tgttttttca   1980

ctcgttcatt ttgtcatctg cttctagatg ctgcaatcaa gaagtagcaa atgcccaagt   2040

tgccatagtg tttgcaggaa aaaaagagaa aaaataataa aaataaggaa ggagcaatgc   2100

caaaaattga agaaaatatt atataattaa agcaagaaga tatctatcca ttgagaaaaa   2160

caatttttat attatttgct tttagcagca aagcattaga attctgagat tgttatagca   2220

ctaagaagat ttttattctg tgtacacact gaaaaataaa attctgagta aagaaagtgt   2280

tcccattccc c                                                        2291


<210>  8255
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  8255

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Asp Lys Leu Ser Leu Glu Gly Ile Val Val Gln 
            100                 105                 110


Arg Ala Glu Cys Arg Pro Ala Ala Ser Glu Asn Tyr Met Arg Leu Lys 
        115                 120                 125


Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg Leu Ser Gln Gln 
    130                 135                 140


Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val Ala Asn His Gln 
145                 150                 155                 160


Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp Gly Lys Arg Ala 
                165                 170                 175


Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe Ser Ala Phe Glu 
            180                 185                 190


Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp Ile Thr Lys Gln 
        195                 200                 205


Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile Gly Val Gln Asn 
    210                 215                 220


Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys Pro Glu Tyr Arg 
225                 230                 235                 240


His Tyr Gln Gly Glu Glu Lys Ser Asp 
                245


<210>  8256
<211>  622
<212>  DNA
<213>  Homo sapiens

<400>  8256
agtgcgcagg cgcagtcccg gctcctggcg gcgtgttcct cttttcctcg gttcccagtg     60

ttctggcagg taaggaacgc cggctcttcg cctctcagcg cggcttgtcc tttgttccgg    120

acgcccgctc ctcagccctg cggctcctgg ggtcgctgct gcatcccgca cgcctccacc    180

ggctgcagac ccatggccga gcgcggggaa ctcgacttga ccggcgccaa acagaacaca    240

ggagtgtggc tagtcaaggt tcctaaatat ttgtcacagc aatgggctaa agcctctgga    300

agaggtgaag ttgggaaact gcggattgcc aagactcaag gaaggactga ggtgtcattt    360

actttgaatg aggatcttgc aaatattcat gatattggtg gaaaaccagc ttcagtcagt    420

gctcctagag aacatccatt tgtcttgcaa agtgttggag gacagacatt aacagtattt    480

actgagagct catcagataa gctgtcattg gaaggaatag tggtacaaag agctgaatgc    540

cgaccagctg ccagtgaaaa ctacatgcga ttaaaaaggc tcctacttac cgtctgaact    600

ttttgcctcc gaccttatct tg                                             622


<210>  8257
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  8257

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Asp Lys Leu Ser Leu Glu Gly Ile Val Val Gln 
            100                 105                 110


Arg Ala Glu Cys Arg Pro Ala Ala Ser Glu Asn Tyr Met Arg Leu Lys 
        115                 120                 125


Arg Leu Leu Leu Thr Val 
    130


<210>  8258
<211>  1374
<212>  DNA
<213>  Homo sapiens

<400>  8258
gcagtcccgg ctcctggcgg cgtgttcctc ttttcctcgg ttcccagtgt tctggcaggt     60

tcctaaatat ttgtcacagc aatgggctaa agcctctgga agaggtgaag ttgggaaact    120

gcggattgcc aagactcaag gaaggactga ggtgtcattt actttgaatg aggatcttgc    180

aaatattcat gatattggtg gaaaaccagc ttcagtcagt gctcctagag aacatccatt    240

tgtcttgcaa agtgttggag gacagacatt aacagtattt actgagagct catcagataa    300

gctgtcattg gaaggaatag tggtacaaag agctgaatgc cgaccagctg ccagtgaaaa    360

ctacatgcga ttaaaaagat tgcaaataga agagtcttcc aaaccagtga ggctatcaca    420

acagctggac aaagttgtaa caaccaatta caaacctgtt gctaatcatc aatacaatat    480

cgaatatgaa aggaaaaaga aagaagacgg aaagcgagct cgagctgata aacaacatgt    540

tttagacatg ctattttcag cctttgagaa acatcaatac tataatctta aggacttggt    600

ggacatcaca aagcaacctg tgaatacctg aagctgggca atttttaaag caaaataatt    660

tgtttcttaa aattttggag gctgagaagt ccaggatcaa agggccacgt ctggtgtacc    720

tgaaggaaat cttaaaagaa attggtgttc agaatgtaaa agggatccac aaaaacacat    780

gggagctgaa gccagagtac agacactatc aaggagaaga aaagagtgac taagaagact    840

cctagccagc atgctagtga aacgactagc agcgatgcta tgcaaaaggc gctgatactg    900

gaaggcttga acaccgtatg ttaatagggg ttaagtgaca gtactttgat ttctctcggt    960

aaatttttta aacctgtaat tcttgtaaag tttcttaact gtttttttga ggagaaagaa   1020

cagatttatt tatagactta acttgtatta aaccagatta ttcacagtag gaataggggt   1080

tggaggatta agagggtttt tcttaaatat tagcttttaa tgtgtacaat taggaaattt   1140

ttttaagtga ggactctcta cccttgccgt atctaaggag ctgaggtaat acagatccaa   1200

ggagaattgt atagcaagaa aaaaacagtc aactacagaa actcttaaaa ggaataaaaa   1260

cccaaagttc cttattttga aattgtcaaa gaacaaagcg gtgtttttct tttaaacagg   1320

tgatcacgtt tcgtgttcat actcaacgtt aataaaagga gagagtttgt agtg         1374


<210>  8259
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  8259

Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg 
1               5                   10                  15


Leu Ser Gln Gln Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val 
            20                  25                  30


Ala Asn His Gln Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp 
        35                  40                  45


Gly Lys Arg Ala Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe 
    50                  55                  60


Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp 
65                  70                  75                  80


Ile Thr Lys Gln Pro Val Asn Thr 
                85


<210>  8260
<211>  2180
<212>  DNA
<213>  Homo sapiens

<400>  8260
gcagtcccgg ctcctggcgg cgtgttcctc ttttcctcgg ttcccagtgt tctggcaggt     60

tcctaaatat ttgtcacagc aatgggctaa agcctctgga agaggtgaag ttgggaaact    120

gcggattgcc aagactcaag gaaggactga ggtgtcattt actttgaatg aggatcttgc    180

aaatattcat gatattggtg gaaaaccagc ttcagtcagt gctcctagag aacatccatt    240

tgtcttgcaa agtgttggag gacagacatt aacagtattt actgagagct catcagataa    300

gctgtcattg gaaggaatag tggtacaaag agctgaatgc cgaccagctg ccagtgaaaa    360

ctacatgcga ttaaaaagat tgcaaataga agagtcttcc aaaccagtga ggctatcaca    420

acagctggac aaagttgtaa caaccaatta caaacctgtt gctaatcatc aatacaatat    480

cgaatatgaa aggaaaaaga aagaagacgg aaagcgagct cgagctgata aacaacatgt    540

tttagacatg ctattttcag cctttgagaa acatcaatac tataatctta aggacttggt    600

ggacatcaca aagcaacctg tgaatacctg aagctgggca atttttaaag caaaataatt    660

tgtttcttaa aattttggag gctgagaagt ccaggatcaa agggccacgt ctggtgtacc    720

tgaaggaaat cttaaaagaa attggtgttc agaatgtaaa agggatccac aaaaacacat    780

gggagctgaa gccagagtac agacactatc aaggagaaga aaagagtgac taagaagact    840

cctagccagc atgctagtga aacgactagc agcgatgcta tgcaaaaggc gctgatactg    900

gaaggcttga acaccgtatg ttaatagggg ttaagtgaca gtactttgat ttctctcggt    960

aaatttttta aacctgtaat tcttgtaaag tttcttaact gtttttttga ggagaaagaa   1020

cagatttatt tatagactta acttgtatta aaccagatta ttcacagtag gaataggggt   1080

tggaggatta agagggtttt tcttaaatat tagcttttaa tgtgtacaat taggaaattt   1140

ttttaagtga ggactctcta cccttgccgt atctaaggag ctgaggtaat acagatccaa   1200

ggagaattgt atagcaagaa aaaaacagtc aactacagaa actcttaaaa ggaataaaaa   1260

cccaaagttc cttattttga aattgtcaaa gaacaaagcg gtgtttttct tttaaacagg   1320

tgatcacgtt tcgtgttcat actcaacgtt aataaaagga gagagtttgt agtgaaatgg   1380

cagtgttcat cattggctta ttttaccgta gtgatgctga gatgagaaat gtgcaggatc   1440

atggtcagtt gatgtttctt ttatttgctt ttaagataat tagaaattaa atatctttcc   1500

aaaatttgaa gatatgtctc ccccagtcag attataagct tctcaaaact ggcttgcccc   1560

cagaatttta ctgcttaccc agcagacatg tattgaccat cacatggcaa atgatatcag   1620

caaatcaaaa gatgggcgta ggggtccagc cgagacagaa aacgttagtt tcaattcctg   1680

gggcattaaa atgttgcttt tctctttctc tttaattaat ttttaaatga aaacaataca   1740

tgtatatgtt agttttttct agcacaacac aatattatat attaagcgat ccaaaatcat   1800

actgtcaaga ccatcaaaca aaacaaagaa gcttaagtga actaagcaca gggaaaagtt   1860

gttttttcac tcgttcattt tgtcatctgc ttctagatgc tgcaatcaag aagtagcaaa   1920

tgcccaagtt gccatagtgt ttgcaggaaa aaaagagaaa aaataataaa aataaggaag   1980

gagcaatgcc aaaaattgaa gaaaatatta tataattaaa gcaagaagat atctatccat   2040

tgagaaaaac aatttttata ttatttgctt ttagcagcaa agcattagaa ttctgagatt   2100

gttatagcac taagaagatt tttattctgt gtacacactg aaaaataaaa ttctgagtaa   2160

agaaagtgtt cccattcccc                                               2180


<210>  8261
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  8261

Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg 
1               5                   10                  15


Leu Ser Gln Gln Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val 
            20                  25                  30


Ala Asn His Gln Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp 
        35                  40                  45


Gly Lys Arg Ala Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe 
    50                  55                  60


Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp 
65                  70                  75                  80


Ile Thr Lys Gln Pro Val Asn Thr 
                85


<210>  8262
<211>  1086
<212>  DNA
<213>  Homo sapiens

<400>  8262
gtgttcctct tttcctcggt tcccagtgtt ctggcaggta aggaacgccg gctcttcgcc     60

tctcagcgcg gcttgtcctt tgttccggac gcccgctcct cagccctgcg gctcctgggg    120

tcgctgctgc atcccgcacg cctccaccgg ctgcagaccc atggccgagc gcggggaact    180

cgacttgacc ggcgccaaac agaacacagg agtgtggcta gtcaaggttc ctaaatattt    240

gtcacagcaa tgggctaaag cctctggaag aggtgaagtt gggaaactgc ggattgccaa    300

gactcaagga aggactgagg tgtcatttac tttgaatgag gatcttgcaa atattcatga    360

tattggtgga aaaccagctt cagtcagtgc tcctagagaa catccatttg tcttgcaaag    420

tgttggagga cagacattaa cagtatttac tgagagctca tcagagtctt tcttggtcac    480

ccaggctagg gtacagtggc acgatcttgg ctcacagcaa cctcttcctc ccgggctcaa    540

gcagttgtcc tgcctcagcc tcctgagtaa ctgggattac aagtgtgcac taccaaccct    600

ggctaattat tgtatttttt ttagaagaga caggatttca ccatgttggc caggctggtc    660

ttgaactccc gacaagtgat ctgcccgcct caacctccca aagtgagcga ctgcacctgg    720

cctcttattc ttttggctca ttcacatact ttcccagaag agtgatttct tataatactg    780

taatacctga aacttgtttc tgtatggaaa caaccataga tgatttcttc gcaggaaaga    840

ggtagatagg gtgtggctgt tcccttgttg gggaactgtt agtttctgta gaagaggttt    900

tagcctttta cttcattagt aatttttaac atgggtggcg ttgattggtg aagtcttttt    960

taactttatt cccccccgcc cttttttttt gagacagggt cttgctctgt cacccaggct   1020

ggagtgcagt ggcatgatcc tacctcactg cagcctcgaa ctcttgggct caagcaatct   1080

tcccac                                                              1086


<210>  8263
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  8263

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Glu Ser Phe Leu Val Thr Gln Ala Arg Val Gln 
            100                 105                 110


Trp His Asp Leu Gly Ser Gln Gln Pro Leu Pro Pro Gly Leu Lys Gln 
        115                 120                 125


Leu Ser Cys Leu Ser Leu Leu Ser Asn Trp Asp Tyr Lys Cys Ala Leu 
    130                 135                 140


Pro Thr Leu Ala Asn Tyr Cys Ile Phe Phe Arg Arg Asp Arg Ile Ser 
145                 150                 155                 160


Pro Cys Trp Pro Gly Trp Ser 
                165


<210>  8264
<211>  588
<212>  DNA
<213>  Homo sapiens

<400>  8264
gtgttcctct tttcctcggt tcccagtgtt ctggcaggta aggaacgccg gctcttcgcc     60

tctcagcgcg gcttgtcctt tgttccggac gcccgctcct cagccctgcg gctcctgggg    120

tcgctgctgc atcccgcacg cctccaccgg ctgcagaccc atggccgagc gcggggaact    180

cgacttgacc ggcgccaaac agaacacagg agtgtggcta gtcaaggttc ctaaatattt    240

gtcacagcaa tgggctaaag cctctggaag aggtgaagtt gggaaactgc ggattgccaa    300

gactcaagga aggactgagg tgtcatttac tttgaatgag gatcttgcaa atattcatga    360

tattggtgga aaaccagctt cagtcagtgc tcctagagaa catccatttg tcttgcaaag    420

tgttggagga cagacattaa cagtatttac tgagagctca tcagggggat ccagaatgac    480

tgctggagtt actactgtca tatctacctc tcaggcatca aaagggaagc aagacgggga    540

agggtctcgc tctgttgccc aggcaggaag tgcagtggca tagtcatg                 588


<210>  8265
<211>  140
<212>  PRT
<213>  Homo sapiens

<400>  8265

Met Ala Glu Arg Gly Glu Leu Asp Leu Thr Gly Ala Lys Gln Asn Thr 
1               5                   10                  15


Gly Val Trp Leu Val Lys Val Pro Lys Tyr Leu Ser Gln Gln Trp Ala 
            20                  25                  30


Lys Ala Ser Gly Arg Gly Glu Val Gly Lys Leu Arg Ile Ala Lys Thr 
        35                  40                  45


Gln Gly Arg Thr Glu Val Ser Phe Thr Leu Asn Glu Asp Leu Ala Asn 
    50                  55                  60


Ile His Asp Ile Gly Gly Lys Pro Ala Ser Val Ser Ala Pro Arg Glu 
65                  70                  75                  80


His Pro Phe Val Leu Gln Ser Val Gly Gly Gln Thr Leu Thr Val Phe 
                85                  90                  95


Thr Glu Ser Ser Ser Gly Gly Ser Arg Met Thr Ala Gly Val Thr Thr 
            100                 105                 110


Val Ile Ser Thr Ser Gln Ala Ser Lys Gly Lys Gln Asp Gly Glu Gly 
        115                 120                 125


Ser Arg Ser Val Ala Gln Ala Gly Ser Ala Val Ala 
    130                 135                 140


<210>  8266
<211>  1863
<212>  DNA
<213>  Homo sapiens

<400>  8266
gcaaaaccga gctgacagcg caggcgatgc tgccagcgtt tccattccat caccaggctg     60

gggctgaata aaggcgtgct tgtgtggtag tgtctctttt taaaaaatct caaagccaag    120

aagaacaagc tgaaatagca tcttcaaaaa atggagcgta aaataaacag aagagaaaaa    180

gaaaaggagt atgaagggaa acacaacagc ctggaagata ctgatcaagg aaagaactgc    240

aaatccacac tgatgaccct caacgttggt ggatatttat acattactca aaaacaaaca    300

ctgaccaagt acccagacac tttccttgaa ggtatagtaa atggaaaaat cctctgcccg    360

tttgatgctg atggtcatta tttcatagac agggatggtc tcctcttcag gcatgtccta    420

aacttcctac gaaatggaga acttctattg cccgaagggt ttcgagaaaa tcaacttctt    480

gcacaagaag cagaattctt tcagctcaag ggactggcag aggaagtgaa atccaggtgg    540

gagaaagaac agctaacacc cagagagact actttcttgg aaataacaga taaccacgat    600

cgttcacaag gattaagaat cttctgtaat gctcctgatt tcatatcaaa aataaagtct    660

cgcattgttc tggtgtccaa aagcaggctg gatggatttc cagaggagtt ttcaatatcg    720

tcaaatatca tccaatttaa atacttcata aagtctgaaa atggcactcg acttgtacta    780

aaggaagaca acacctttgt ctgtaccttg gaaactctta agtttgaggc tatcatgatg    840

gctttaaagt gtggctttag actgctgacc agcctggatt gttccaaagg gtcaattgtt    900

cacagcgatg cacttcattt tatcaagtaa ttacctgtgt cacgaacaaa ggcaacaagc    960

atgcagccag caagcttcgg aaaaccacag catcaaagac atcccaaata acatgcccag   1020

ctagctctgt actacagagc cctgctacta atcaattact gtgagctaac ggtatgtaaa   1080

ttctatcgct aaagatgtcc ttcctctggg gtgttcctac tgatcagact cttccaccta   1140

aaatgaaaac agtaaccttc tatatactgt aaataaagac tgaaagcttt tgctatttat   1200

ttgtccttaa gctgtctttc aattcagatt gtcttgggta tttgcacaaa aaagaaagca   1260

tgtacattat ctatcgttca tttaagtaaa tggtaataaa atattttaag gggctattaa   1320

tatttaaaat ccttttctac tatggcaaaa atctacagag aaactgaact ggcaaaatta   1380

actacctgga gcaaaacaga tgtgcagatc taactaaaac agagctatag tgaaacaaaa   1440

tgagattgta agaagacatt aaagctattg atttgatttt tccatagcaa gcaccaaaag   1500

cttatattca cagttcctgt gtttcatatt agacttatag ctgaattggt attttgctga   1560

aaattcctag aaaactgctt gatgacaata aaaagtaaat aaaagcactg ctaccttctt   1620

tgattgtatt aatgattata ataaaaagtt acaggtcact ttaaaagcaa acagtaccac   1680

ttgatgattt tgcataaaat tatgcattga tgtcaaccgg caggctacag gaaccctggc   1740

tggtcctgga agtgacaaaa accagcaaat tcaattcttt gcaggctgag ttcccacaaa   1800

gcatgggtaa cttagtctca atagagtatc tgttattaga ataataaagg agttcatttt   1860

cag                                                                 1863


<210>  8267
<211>  259
<212>  PRT
<213>  Homo sapiens

<400>  8267

Met Glu Arg Lys Ile Asn Arg Arg Glu Lys Glu Lys Glu Tyr Glu Gly 
1               5                   10                  15


Lys His Asn Ser Leu Glu Asp Thr Asp Gln Gly Lys Asn Cys Lys Ser 
            20                  25                  30


Thr Leu Met Thr Leu Asn Val Gly Gly Tyr Leu Tyr Ile Thr Gln Lys 
        35                  40                  45


Gln Thr Leu Thr Lys Tyr Pro Asp Thr Phe Leu Glu Gly Ile Val Asn 
    50                  55                  60


Gly Lys Ile Leu Cys Pro Phe Asp Ala Asp Gly His Tyr Phe Ile Asp 
65                  70                  75                  80


Arg Asp Gly Leu Leu Phe Arg His Val Leu Asn Phe Leu Arg Asn Gly 
                85                  90                  95


Glu Leu Leu Leu Pro Glu Gly Phe Arg Glu Asn Gln Leu Leu Ala Gln 
            100                 105                 110


Glu Ala Glu Phe Phe Gln Leu Lys Gly Leu Ala Glu Glu Val Lys Ser 
        115                 120                 125


Arg Trp Glu Lys Glu Gln Leu Thr Pro Arg Glu Thr Thr Phe Leu Glu 
    130                 135                 140


Ile Thr Asp Asn His Asp Arg Ser Gln Gly Leu Arg Ile Phe Cys Asn 
145                 150                 155                 160


Ala Pro Asp Phe Ile Ser Lys Ile Lys Ser Arg Ile Val Leu Val Ser 
                165                 170                 175


Lys Ser Arg Leu Asp Gly Phe Pro Glu Glu Phe Ser Ile Ser Ser Asn 
            180                 185                 190


Ile Ile Gln Phe Lys Tyr Phe Ile Lys Ser Glu Asn Gly Thr Arg Leu 
        195                 200                 205


Val Leu Lys Glu Asp Asn Thr Phe Val Cys Thr Leu Glu Thr Leu Lys 
    210                 215                 220


Phe Glu Ala Ile Met Met Ala Leu Lys Cys Gly Phe Arg Leu Leu Thr 
225                 230                 235                 240


Ser Leu Asp Cys Ser Lys Gly Ser Ile Val His Ser Asp Ala Leu His 
                245                 250                 255


Phe Ile Lys 



<210>  8268
<211>  1872
<212>  DNA
<213>  Homo sapiens

<400>  8268
tttccacaag accttctgga tccagctgaa tgtggaggcc tttaagagaa cttccagctc     60

ctgtaaaaac ccagaccaga ggactactga ccaacatttc aggctgatcc tccagacctc    120

gaagttactc tccttactct cctgactctt aattacatca cacctgtgtc gacactctct    180

gggaaaagac tgaagaaata atcttttcaa gaagcagaaa gctcctgcat acataggctg    240

atacgccacc tactgcaaaa ccgagctgac agcgcaggcg atgctgccag cgtttccatt    300

ccatcaccag gctggggctg aataaaggcg tgcttgtgtg gtagtgtctc tttttaaaaa    360

atctcaaagc caagaagaac aagctgaaat agcatcttca aaaaatggag cgtaaaataa    420

acagaagaga aaaagaaaag gagtatgaag ggaaacacaa cagcctggaa gatactgatc    480

aaggaaagaa ctgcaaatcc acactgatga ccctcaacgt tggtggatat ttatacatta    540

ctcaaaaaca aacactgacc aagtacccag acactttcct tgaaggtata gtaaatggaa    600

aaatcctctg cccgtttgat gctgatggtc attatttcat agacagggat ggtctcctct    660

tcaggcatgt cctaaacttc ctacgaaatg gagaacttct attgcccgaa gggtttcgag    720

aaaatcaact tcttgcacaa gaagcagaat tctttcagct caagggactg gcagaggaag    780

tgaaatccag gtgggagaaa gaacagctaa cacccagaga gactactttc ttggaaataa    840

cagataacca cgatcgttca caaggattaa gaatcttctg taatgctcct gatttcatat    900

caaaaataaa gtctcgcatt gttctggtgt ccaaaagcag gctggatgga tttccagagg    960

agttttcaat atcgtcaaat atcatccaat ttaaatactt cataaagtct gaaaatggca   1020

ctcgacttgt actaaaggaa gacaacacct ttgtctgtac cttggaaact cttaagtttg   1080

aggctatcat gatggcttta aagtgtggct ttagactgct gaccagcctg gattgttcca   1140

aagggtcaat tgttcacagc gatgcacttc attttatcaa gtaattacct gtgtcacgaa   1200

caaaggcaac aagcatgcag ccagcaagct tcggaaaacc acagcatcaa agacatccca   1260

aataacatgc ccagctagct ctgtactaca gagccctgct actaatcaat tactgtgagc   1320

taacggtatg taaattctat cgctaaagat gtccttcctc tggggtgttc ctactgatca   1380

gactcttcca cctaaaatga aaacagtaac cttctatata ctgtaaataa agactgaaag   1440

cttttgctat ttatttgtcc ttaagctgtc tttcaattca gattgtcttg ggtatttgca   1500

caaaaaagaa agcatgtaca ttatctatcg ttcatttaag taaatggtaa taaaatattt   1560

taaggggcta ttaatattta aaatcctttt ctactatggc aaaaatctac agagaaactg   1620

aactggcaaa attaactacc tggagcaaaa cagatgtgca gatctaacta aaacagagct   1680

atagtgaaac aaaatgagat tgtaagaaga cattaaagct attgatttga tttttccata   1740

gcaagcacca aaagcttata ttcacagttc ctgtgtttca tattagactt atagctgaat   1800

tggtattttg ctgaaaattc ctagaaaact gcttgatgac aataaaaagt aaataaaagc   1860

actgctacct tc                                                       1872


<210>  8269
<211>  259
<212>  PRT
<213>  Homo sapiens

<400>  8269

Met Glu Arg Lys Ile Asn Arg Arg Glu Lys Glu Lys Glu Tyr Glu Gly 
1               5                   10                  15


Lys His Asn Ser Leu Glu Asp Thr Asp Gln Gly Lys Asn Cys Lys Ser 
            20                  25                  30


Thr Leu Met Thr Leu Asn Val Gly Gly Tyr Leu Tyr Ile Thr Gln Lys 
        35                  40                  45


Gln Thr Leu Thr Lys Tyr Pro Asp Thr Phe Leu Glu Gly Ile Val Asn 
    50                  55                  60


Gly Lys Ile Leu Cys Pro Phe Asp Ala Asp Gly His Tyr Phe Ile Asp 
65                  70                  75                  80


Arg Asp Gly Leu Leu Phe Arg His Val Leu Asn Phe Leu Arg Asn Gly 
                85                  90                  95


Glu Leu Leu Leu Pro Glu Gly Phe Arg Glu Asn Gln Leu Leu Ala Gln 
            100                 105                 110


Glu Ala Glu Phe Phe Gln Leu Lys Gly Leu Ala Glu Glu Val Lys Ser 
        115                 120                 125


Arg Trp Glu Lys Glu Gln Leu Thr Pro Arg Glu Thr Thr Phe Leu Glu 
    130                 135                 140


Ile Thr Asp Asn His Asp Arg Ser Gln Gly Leu Arg Ile Phe Cys Asn 
145                 150                 155                 160


Ala Pro Asp Phe Ile Ser Lys Ile Lys Ser Arg Ile Val Leu Val Ser 
                165                 170                 175


Lys Ser Arg Leu Asp Gly Phe Pro Glu Glu Phe Ser Ile Ser Ser Asn 
            180                 185                 190


Ile Ile Gln Phe Lys Tyr Phe Ile Lys Ser Glu Asn Gly Thr Arg Leu 
        195                 200                 205


Val Leu Lys Glu Asp Asn Thr Phe Val Cys Thr Leu Glu Thr Leu Lys 
    210                 215                 220


Phe Glu Ala Ile Met Met Ala Leu Lys Cys Gly Phe Arg Leu Leu Thr 
225                 230                 235                 240


Ser Leu Asp Cys Ser Lys Gly Ser Ile Val His Ser Asp Ala Leu His 
                245                 250                 255


Phe Ile Lys 



<210>  8270
<211>  1117
<212>  DNA
<213>  Homo sapiens

<400>  8270
tataagaatt actaaggata ggggaaattg cctttctgtt tggacaaata ttcatagcag     60

ttaaagattc tgttttgaca tgcccagatt tagaattctg caggaaaaca gaagtcagag    120

cagctggcag gctgaactgg tacacaatat aacccagaca gtagacctgc ccagtgtcac    180

agtattttct gggctggctg ttttagtcac aagataagct gtcattggaa ggaatagtgg    240

tacaaagagc tgaatgccga ccagctgcca gtgaaaacta catgcgatta aaaagattgc    300

aaatagaaga gtcttccaaa ccagtgaggc tatcacaaca gctggacaaa gttgtaacaa    360

ccaattacaa acctgttgct aatcatcaat acaatatcga atatgaaagg aaaaagaaag    420

aagacggaaa gcgagctcga gctgataaac aacatgtttt agacatgcta ttttcagcct    480

ttgagaaaca tcaatactat aatcttaagg acttggtgga catcacaaag caacctgtgg    540

tgtacctgaa ggaaatctta aaagaaattg gtgttcagaa tgtaaaaggg atccacaaaa    600

acacatggga gctgaagcca gagtacagac actatcaagg agaagaaaag agtgactaag    660

aagactccta gccagcatgc tagtgaaacg actagcagcg atgctatgca aaaggcgctg    720

atactggaag gcttgaacac cgtatgttaa taggggttaa gtgacagtac tttgatttct    780

ctcggtaaat tttttaaacc tgtaattctt gtaaagtttc ttaactgttt ttttgaggag    840

aaagaacaga tttatttata gacttaactt gtattaaacc agattattca cagtaggaat    900

aggggttgga ggattaagag ggtttttctt aaatattagc ttttaatgtg tacaattagg    960

aaattttttt aagtgaggac tctctaccct tgccgtatct aaggagctga ggtaatacag   1020

atccaaggag aattgtatag caagaaaaaa acagtcaact acagaaactc ttaaaaggaa   1080

taaaaaccca aagttcctta ttttgaaatt gtcaaag                            1117


<210>  8271
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  8271

Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg 
1               5                   10                  15


Leu Ser Gln Gln Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val 
            20                  25                  30


Ala Asn His Gln Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp 
        35                  40                  45


Gly Lys Arg Ala Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe 
    50                  55                  60


Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp 
65                  70                  75                  80


Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile 
                85                  90                  95


Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys 
            100                 105                 110


Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
        115                 120                 125


<210>  8272
<211>  1200
<212>  DNA
<213>  Homo sapiens

<400>  8272
tataagaatt actaaggata ggggaaattg cctttctgtt tggacaaata ttcatagcag     60

ttaaagattc tgttttgaca tgcccagatt tagaattctg caggaaaaca gaagtcagag    120

cagctggcag gctgaactgg tacacaatat aacccagaca gtagacctgc ccagtgtcac    180

agtattttct gggctggctg ttttagtcac aagataagct gtcattggaa ggaatagtgg    240

tacaaagagc tgaatgccga ccagctgcca gtgaaaacta catgcgatta aaaagattgc    300

aaatagaaga gtcttccaaa ccagtgaggc tatcacaaca gctggacaaa gttgtaacaa    360

ccaattacaa acctgttgct aatcatcaat acaatatcga atatgaaagg aaaaagaaag    420

aagacggaaa gcgagctcga gctgataaac aacatgtttt agacatgcta ttttcagcct    480

ttgagaaaca tcaatactat aatcttaagg acttggtgga catcacaaag caacctgtgg    540

tgtacctgaa ggaaatctta aaagaaattg gtgttcagaa tgtaaaaggg atccacaaaa    600

acacatggga gctgaagcca gagtacagac actatcaagg agaagaaaag agtgactaag    660

aagactccta gccagcatgc tagtgaaacg actagcagcg atgctatgca aaaggcgctg    720

atactggaag gcttgaacac cgtatgttaa taggggttaa gtgacagtac tttgatttct    780

ctcggtaaat tttttaaacc tgtaattctt gtaaagtttc ttaactgttt ttttgaggag    840

aaagaacaga tttatttata gacttaactt gtattaaacc agattattca cagtaggaat    900

aggggttgga ggattaagag ggtttttctt aaatattagc ttttaatgtg tacaattagg    960

aaattttttt aagtgaggac tctctaccct tgccgtatct aaggagctga ggtaatacag   1020

atccaaggag aattgtatag caagaaaaaa acagtcaact acagaaactc ttaaaaggaa   1080

taaaaaccca aagttcctta ttttgaaatt gtcaaagaac aaagcggtgt ttttctttta   1140

aacaggtgat cacgtttcgt gttcatactc aacgttaata aaaggagaga gtttgtagtg   1200


<210>  8273
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  8273

Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg 
1               5                   10                  15


Leu Ser Gln Gln Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val 
            20                  25                  30


Ala Asn His Gln Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp 
        35                  40                  45


Gly Lys Arg Ala Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe 
    50                  55                  60


Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp 
65                  70                  75                  80


Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile 
                85                  90                  95


Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys 
            100                 105                 110


Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
        115                 120                 125


<210>  8274
<211>  2006
<212>  DNA
<213>  Homo sapiens

<400>  8274
tataagaatt actaaggata ggggaaattg cctttctgtt tggacaaata ttcatagcag     60

ttaaagattc tgttttgaca tgcccagatt tagaattctg caggaaaaca gaagtcagag    120

cagctggcag gctgaactgg tacacaatat aacccagaca gtagacctgc ccagtgtcac    180

agtattttct gggctggctg ttttagtcac aagataagct gtcattggaa ggaatagtgg    240

tacaaagagc tgaatgccga ccagctgcca gtgaaaacta catgcgatta aaaagattgc    300

aaatagaaga gtcttccaaa ccagtgaggc tatcacaaca gctggacaaa gttgtaacaa    360

ccaattacaa acctgttgct aatcatcaat acaatatcga atatgaaagg aaaaagaaag    420

aagacggaaa gcgagctcga gctgataaac aacatgtttt agacatgcta ttttcagcct    480

ttgagaaaca tcaatactat aatcttaagg acttggtgga catcacaaag caacctgtgg    540

tgtacctgaa ggaaatctta aaagaaattg gtgttcagaa tgtaaaaggg atccacaaaa    600

acacatggga gctgaagcca gagtacagac actatcaagg agaagaaaag agtgactaag    660

aagactccta gccagcatgc tagtgaaacg actagcagcg atgctatgca aaaggcgctg    720

atactggaag gcttgaacac cgtatgttaa taggggttaa gtgacagtac tttgatttct    780

ctcggtaaat tttttaaacc tgtaattctt gtaaagtttc ttaactgttt ttttgaggag    840

aaagaacaga tttatttata gacttaactt gtattaaacc agattattca cagtaggaat    900

aggggttgga ggattaagag ggtttttctt aaatattagc ttttaatgtg tacaattagg    960

aaattttttt aagtgaggac tctctaccct tgccgtatct aaggagctga ggtaatacag   1020

atccaaggag aattgtatag caagaaaaaa acagtcaact acagaaactc ttaaaaggaa   1080

taaaaaccca aagttcctta ttttgaaatt gtcaaagaac aaagcggtgt ttttctttta   1140

aacaggtgat cacgtttcgt gttcatactc aacgttaata aaaggagaga gtttgtagtg   1200

aaatggcagt gttcatcatt ggcttatttt accgtagtga tgctgagatg agaaatgtgc   1260

aggatcatgg tcagttgatg tttcttttat ttgcttttaa gataattaga aattaaatat   1320

ctttccaaaa tttgaagata tgtctccccc agtcagatta taagcttctc aaaactggct   1380

tgcccccaga attttactgc ttacccagca gacatgtatt gaccatcaca tggcaaatga   1440

tatcagcaaa tcaaaagatg ggcgtagggg tccagccgag acagaaaacg ttagtttcaa   1500

ttcctggggc attaaaatgt tgcttttctc tttctcttta attaattttt aaatgaaaac   1560

aatacatgta tatgttagtt ttttctagca caacacaata ttatatatta agcgatccaa   1620

aatcatactg tcaagaccat caaacaaaac aaagaagctt aagtgaacta agcacaggga   1680

aaagttgttt tttcactcgt tcattttgtc atctgcttct agatgctgca atcaagaagt   1740

agcaaatgcc caagttgcca tagtgtttgc aggaaaaaaa gagaaaaaat aataaaaata   1800

aggaaggagc aatgccaaaa attgaagaaa atattatata attaaagcaa gaagatatct   1860

atccattgag aaaaacaatt tttatattat ttgcttttag cagcaaagca ttagaattct   1920

gagattgtta tagcactaag aagattttta ttctgtgtac acactgaaaa ataaaattct   1980

gagtaaagaa agtgttccca ttcccc                                        2006


<210>  8275
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  8275

Met Arg Leu Lys Arg Leu Gln Ile Glu Glu Ser Ser Lys Pro Val Arg 
1               5                   10                  15


Leu Ser Gln Gln Leu Asp Lys Val Val Thr Thr Asn Tyr Lys Pro Val 
            20                  25                  30


Ala Asn His Gln Tyr Asn Ile Glu Tyr Glu Arg Lys Lys Lys Glu Asp 
        35                  40                  45


Gly Lys Arg Ala Arg Ala Asp Lys Gln His Val Leu Asp Met Leu Phe 
    50                  55                  60


Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp Leu Val Asp 
65                  70                  75                  80


Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu Lys Glu Ile 
                85                  90                  95


Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp Glu Leu Lys 
            100                 105                 110


Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
        115                 120                 125


<210>  8276
<211>  1133
<212>  DNA
<213>  Homo sapiens

<400>  8276
attcgtagga aaagagaaag gagcagctgg tactgtctct ctcctccctc ttattgaatg     60

accttcaaag tcccacaact taaaccaaca ttgttagtac catggttccg ttacattata    120

aaataaatac aagattcata taagatgtaa aatggtctca ttcttttagt ttggaatttt    180

tatctaattt ctgatttttt aatttaaaag cgaactttga tagcatgatt gaattgaatt    240

tcaaagctcc atatttctgc aggagaggct cctacttacc gtctgaactt tttgcctccg    300

accttatctt gattgcaaat agaagagtct tccaaaccag tgaggctatc acaacagctg    360

gacaaagttg taacaaccaa ttacaaacct gttgctaatc atcaatacaa tatcgaatat    420

gaaaggaaaa agaaagaaga cggaaagcga gctcgagctg ataaacaaca tgttttagac    480

atgctatttt cagcctttga gaaacatcaa tactataatc ttaaggactt ggtggacatc    540

acaaagcaac ctgtggtgta cctgaaggaa atcttaaaag aaattggtgt tcagaatgta    600

aaagggatcc acaaaaacac atgggagctg aagccagagt acagacacta tcaaggagaa    660

gaaaagagtg actaagaaga ctcctagcca gcatgctagt gaaacgacta gcagcgatgc    720

tatgcaaaag gcgctgatac tggaaggctt gaacaccgta tgttaatagg ggttaagtga    780

cagtactttg atttctctcg gtaaattttt taaacctgta attcttgtaa agtttcttaa    840

ctgttttttt gaggagaaag aacagattta tttatagact taacttgtat taaaccagat    900

tattcacagt aggaataggg gttggaggat taagagggtt tttcttaaat attagctttt    960

aatgtgtaca attaggaaat ttttttaagt gaggactctc tacccttgcc gtatctaagg   1020

agctgaggta atacagatcc aaggagaatt gtatagcaag aaaaaaacag tcaactacag   1080

aaactcttaa aaggaataaa aacccaaagt tccttatttt gaaattgtca aag          1133


<210>  8277
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8277

Met Leu Phe Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp 
1               5                   10                  15


Leu Val Asp Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu 
            20                  25                  30


Lys Glu Ile Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp 
        35                  40                  45


Glu Leu Lys Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
    50                  55                  60


<210>  8278
<211>  1216
<212>  DNA
<213>  Homo sapiens

<400>  8278
attcgtagga aaagagaaag gagcagctgg tactgtctct ctcctccctc ttattgaatg     60

accttcaaag tcccacaact taaaccaaca ttgttagtac catggttccg ttacattata    120

aaataaatac aagattcata taagatgtaa aatggtctca ttcttttagt ttggaatttt    180

tatctaattt ctgatttttt aatttaaaag cgaactttga tagcatgatt gaattgaatt    240

tcaaagctcc atatttctgc aggagaggct cctacttacc gtctgaactt tttgcctccg    300

accttatctt gattgcaaat agaagagtct tccaaaccag tgaggctatc acaacagctg    360

gacaaagttg taacaaccaa ttacaaacct gttgctaatc atcaatacaa tatcgaatat    420

gaaaggaaaa agaaagaaga cggaaagcga gctcgagctg ataaacaaca tgttttagac    480

atgctatttt cagcctttga gaaacatcaa tactataatc ttaaggactt ggtggacatc    540

acaaagcaac ctgtggtgta cctgaaggaa atcttaaaag aaattggtgt tcagaatgta    600

aaagggatcc acaaaaacac atgggagctg aagccagagt acagacacta tcaaggagaa    660

gaaaagagtg actaagaaga ctcctagcca gcatgctagt gaaacgacta gcagcgatgc    720

tatgcaaaag gcgctgatac tggaaggctt gaacaccgta tgttaatagg ggttaagtga    780

cagtactttg atttctctcg gtaaattttt taaacctgta attcttgtaa agtttcttaa    840

ctgttttttt gaggagaaag aacagattta tttatagact taacttgtat taaaccagat    900

tattcacagt aggaataggg gttggaggat taagagggtt tttcttaaat attagctttt    960

aatgtgtaca attaggaaat ttttttaagt gaggactctc tacccttgcc gtatctaagg   1020

agctgaggta atacagatcc aaggagaatt gtatagcaag aaaaaaacag tcaactacag   1080

aaactcttaa aaggaataaa aacccaaagt tccttatttt gaaattgtca aagaacaaag   1140

cggtgttttt cttttaaaca ggtgatcacg tttcgtgttc atactcaacg ttaataaaag   1200

gagagagttt gtagtg                                                   1216


<210>  8279
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8279

Met Leu Phe Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp 
1               5                   10                  15


Leu Val Asp Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu 
            20                  25                  30


Lys Glu Ile Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp 
        35                  40                  45


Glu Leu Lys Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
    50                  55                  60


<210>  8280
<211>  2022
<212>  DNA
<213>  Homo sapiens

<400>  8280
attcgtagga aaagagaaag gagcagctgg tactgtctct ctcctccctc ttattgaatg     60

accttcaaag tcccacaact taaaccaaca ttgttagtac catggttccg ttacattata    120

aaataaatac aagattcata taagatgtaa aatggtctca ttcttttagt ttggaatttt    180

tatctaattt ctgatttttt aatttaaaag cgaactttga tagcatgatt gaattgaatt    240

tcaaagctcc atatttctgc aggagaggct cctacttacc gtctgaactt tttgcctccg    300

accttatctt gattgcaaat agaagagtct tccaaaccag tgaggctatc acaacagctg    360

gacaaagttg taacaaccaa ttacaaacct gttgctaatc atcaatacaa tatcgaatat    420

gaaaggaaaa agaaagaaga cggaaagcga gctcgagctg ataaacaaca tgttttagac    480

atgctatttt cagcctttga gaaacatcaa tactataatc ttaaggactt ggtggacatc    540

acaaagcaac ctgtggtgta cctgaaggaa atcttaaaag aaattggtgt tcagaatgta    600

aaagggatcc acaaaaacac atgggagctg aagccagagt acagacacta tcaaggagaa    660

gaaaagagtg actaagaaga ctcctagcca gcatgctagt gaaacgacta gcagcgatgc    720

tatgcaaaag gcgctgatac tggaaggctt gaacaccgta tgttaatagg ggttaagtga    780

cagtactttg atttctctcg gtaaattttt taaacctgta attcttgtaa agtttcttaa    840

ctgttttttt gaggagaaag aacagattta tttatagact taacttgtat taaaccagat    900

tattcacagt aggaataggg gttggaggat taagagggtt tttcttaaat attagctttt    960

aatgtgtaca attaggaaat ttttttaagt gaggactctc tacccttgcc gtatctaagg   1020

agctgaggta atacagatcc aaggagaatt gtatagcaag aaaaaaacag tcaactacag   1080

aaactcttaa aaggaataaa aacccaaagt tccttatttt gaaattgtca aagaacaaag   1140

cggtgttttt cttttaaaca ggtgatcacg tttcgtgttc atactcaacg ttaataaaag   1200

gagagagttt gtagtgaaat ggcagtgttc atcattggct tattttaccg tagtgatgct   1260

gagatgagaa atgtgcagga tcatggtcag ttgatgtttc ttttatttgc ttttaagata   1320

attagaaatt aaatatcttt ccaaaatttg aagatatgtc tcccccagtc agattataag   1380

cttctcaaaa ctggcttgcc cccagaattt tactgcttac ccagcagaca tgtattgacc   1440

atcacatggc aaatgatatc agcaaatcaa aagatgggcg taggggtcca gccgagacag   1500

aaaacgttag tttcaattcc tggggcatta aaatgttgct tttctctttc tctttaatta   1560

atttttaaat gaaaacaata catgtatatg ttagtttttt ctagcacaac acaatattat   1620

atattaagcg atccaaaatc atactgtcaa gaccatcaaa caaaacaaag aagcttaagt   1680

gaactaagca cagggaaaag ttgttttttc actcgttcat tttgtcatct gcttctagat   1740

gctgcaatca agaagtagca aatgcccaag ttgccatagt gtttgcagga aaaaaagaga   1800

aaaaataata aaaataagga aggagcaatg ccaaaaattg aagaaaatat tatataatta   1860

aagcaagaag atatctatcc attgagaaaa acaattttta tattatttgc ttttagcagc   1920

aaagcattag aattctgaga ttgttatagc actaagaaga tttttattct gtgtacacac   1980

tgaaaaataa aattctgagt aaagaaagtg ttcccattcc cc                      2022


<210>  8281
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8281

Met Leu Phe Ser Ala Phe Glu Lys His Gln Tyr Tyr Asn Leu Lys Asp 
1               5                   10                  15


Leu Val Asp Ile Thr Lys Gln Pro Val Val Tyr Leu Lys Glu Ile Leu 
            20                  25                  30


Lys Glu Ile Gly Val Gln Asn Val Lys Gly Ile His Lys Asn Thr Trp 
        35                  40                  45


Glu Leu Lys Pro Glu Tyr Arg His Tyr Gln Gly Glu Glu Lys Ser Asp 
    50                  55                  60


<210>  8282
<211>  581
<212>  DNA
<213>  Homo sapiens

<400>  8282
gaggagccct gaagtggcgg tcaagcttga ggcgtcatct ggctgcgcct agtgggccgt     60

tgccttacag ttgctgagag gaggcgagag gcgggggcgc tagggccgag atcatgtctg    120

actgggagag gtttccttgg cagcagagga cgctaggttt gggatgaaag aagctgggca    180

gatgcaaaat ctggagagcg cgagggccgg gcggtcagtc agcacccaga ctggcagcat    240

gaccggtcag ataccaaggc tttctaaagt caaccttttc actctgctca gcctctggat    300

ggagctcttt ccagcagaag cccagcggca aaaatctcag aaaaatgaag agggaaagca    360

tggaccctta ggagataatg aagagaggac cagagtatct actgacaaaa gacaggtaaa    420

tttttatgat ttcacatata tatgctcata ataacaaagc aaaaggaata gtataaagta    480

gaataaaagt gcctccattt ctactatcaa gggagttttt aaaatactct tctaaaaatg    540

gtctgtatat ttacaagact atatgtcact cctttttttt a                        581


<210>  8283
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  8283

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Val Asn Phe Tyr Asp Phe Thr Tyr Ile Cys Ser 
                85                  90                  95


<210>  8284
<211>  852
<212>  DNA
<213>  Homo sapiens

<400>  8284
atctggctgc gcctagtggg ccgttgcctt acagttgctg agaggaggcg agaggcgggg     60

gcgctagggc cgagatcatg tctgactggg agaggtttcc ttggcagcag aggacgctag    120

gtttgggatg aaagaagctg ggcagatgca aaatctggag agcgcgaggg ccgggcggtc    180

agtcagcacc cagactggca gcatgaccgg tcagatacca aggctttcta aagtcaacct    240

tttcactctg ctcagcctct ggatggagct ctttccagca gaagcccagc ggcaaaaatc    300

tcagaaaaat gaagagggaa agcatggacc cttaggagat aatgaagaga ggaccagagt    360

atctactgac aaaagacagg taaagagaac tggtcttgtg gtggtgaaaa acatgaaaat    420

tgttggtctc cactgttcta gtgaagattt acatgccggg cagattgctc ttattaaaca    480

tgggtcaagg ctgaaaaact gtgatcttta tttttccaga aaaccatgtt ctgcttgttt    540

gaaaatgatt gtaaatgctg gagttaaccg aatttcatac tggcctgctg atccagaaat    600

aagtttgctt acggaggctt ctagttctga agatgcaaag ttagatgcca aagcagtgga    660

aagattgaag tcaaacagtc gggcccatgt gtgtgtctta cttcaacctt tggtgtgtta    720

tatggtgcag tttgtagagg agacctctta caaatgtgac tttattcaaa aaattacaaa    780

aacattgccg gatgctaaca ctgactttta ttatgaatgt aaacaagaaa gaataaaaga    840

atatgaaatg tt                                                        852


<210>  8285
<211>  240
<212>  PRT
<213>  Homo sapiens

<400>  8285

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Val Lys Arg Thr Gly Leu Val Val Val Lys Asn Met 
                85                  90                  95


Lys Ile Val Gly Leu His Cys Ser Ser Glu Asp Leu His Ala Gly Gln 
            100                 105                 110


Ile Ala Leu Ile Lys His Gly Ser Arg Leu Lys Asn Cys Asp Leu Tyr 
        115                 120                 125


Phe Ser Arg Lys Pro Cys Ser Ala Cys Leu Lys Met Ile Val Asn Ala 
    130                 135                 140


Gly Val Asn Arg Ile Ser Tyr Trp Pro Ala Asp Pro Glu Ile Ser Leu 
145                 150                 155                 160


Leu Thr Glu Ala Ser Ser Ser Glu Asp Ala Lys Leu Asp Ala Lys Ala 
                165                 170                 175


Val Glu Arg Leu Lys Ser Asn Ser Arg Ala His Val Cys Val Leu Leu 
            180                 185                 190


Gln Pro Leu Val Cys Tyr Met Val Gln Phe Val Glu Glu Thr Ser Tyr 
        195                 200                 205


Lys Cys Asp Phe Ile Gln Lys Ile Thr Lys Thr Leu Pro Asp Ala Asn 
    210                 215                 220


Thr Asp Phe Tyr Tyr Glu Cys Lys Gln Glu Arg Ile Lys Glu Tyr Glu 
225                 230                 235                 240


<210>  8286
<211>  977
<212>  DNA
<213>  Homo sapiens

<400>  8286
atctggctgc gcctagtggg ccgttgcctt acagttgctg agaggaggcg agaggcgggg     60

gcgctagggc cgagatcatg tctgactggg agaggtttcc ttggcagcag aggacgctag    120

gtttgggatg aaagaagctg ggcagatgca aaatctggag agcgcgaggg ccgggcggtc    180

agtcagcacc cagactggca gcatgaccgg tcagatacca aggctttcta aagtcaacct    240

tttcactctg ctcagcctct ggatggagct ctttccagca gaagcccagc ggcaaaaatc    300

tcagaaaaat gaagagggaa agcatggacc cttaggagat aatgaagaga ggaccagagt    360

atctactgac aaaagacagg taaagagaac tggtcttgtg gtggtgaaaa acatgaaaat    420

tgttggtctc cactgttcta gtgaagattt acatgccggg cagattgctc ttattaaaca    480

tgggtcaagg ctgaaaaact gtgatcttta tttttccaga aaaccatgtt ctgcttgttt    540

gaaaatgatt gtaaatggat tactggaagc agctaagatg cctagatgaa aggtttacca    600

tcactgctgg ttaggaaatg gattatgaga actcgaacag agggaaggtg aaatgcaacc    660

ggaggaaaca ctctgatatg agctggagtt aaccgaattt catactggcc tgctgatcca    720

gaaataagtt tgcttacgga ggcttctagt tctgaagatg caaagttaga tgccaaagca    780

gtggaaagat tgaagtcaaa cagtcgggcc catgtgtgtg tcttacttca acctttggtg    840

tgttatatgg tgcagtttgt agaggagacc tcttacaaat gtgactttat tcaaaaaatt    900

acaaaaacat tgccggatgc taacactgac ttttattatg aatgtaaaca agaaagaata    960

aaagaatatg aaatgtt                                                   977


<210>  8287
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  8287

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Val Lys Arg Thr Gly Leu Val Val Val Lys Asn Met 
                85                  90                  95


Lys Ile Val Gly Leu His Cys Ser Ser Glu Asp Leu His Ala Gly Gln 
            100                 105                 110


Ile Ala Leu Ile Lys His Gly Ser Arg Leu Lys Asn Cys Asp Leu Tyr 
        115                 120                 125


Phe Ser Arg Lys Pro Cys Ser Ala Cys Leu Lys Met Ile Val Asn Gly 
    130                 135                 140


Leu Leu Glu Ala Ala Lys Met Pro Arg 
145                 150


<210>  8288
<211>  3401
<212>  DNA
<213>  Homo sapiens

<400>  8288
atctggctgc gcctagtggg ccgttgcctt acagttgctg agaggaggcg agaggcgggg     60

gcgctagggc cgagatcatg tctgactggg agaggtttcc ttggcagcag aggacgctag    120

gtttgggatg aaagaagctg ggcagatgca aaatctggag agcgcgaggg ccgggcggtc    180

agtcagcacc cagactggca gcatgaccgg tcagatacca aggctttcta aagtcaacct    240

tttcactctg ctcagcctct ggatggagct ctttccagca gaagcccagc ggcaaaaatc    300

tcagaaaaat gaagagggaa agcatggacc cttaggagat aatgaagaga ggaccagagt    360

atctactgac aaaagacagg taaagagaac tggtcttgtg gtggtgaaaa acatgaaaat    420

tgttggtctc cactgttcta gtgaagattt acatgccggg cagattgctc ttattaaaca    480

tgggtcaagg ctgaaaaact gtgatcttta tttttccaga aaaccatgtt ctgcttgttt    540

gaaaatgatt gtaaatgctg gagttaaccg aatttcatac tggcctgctg atccagaaat    600

aagtttgctt acggaggctt ctagttctga agatgcaaag ttagatgcca aagcagtgga    660

aagattgaag tcaaacagtc gggcccatgt gtgtgtctta cttcaacctt tggtgtgtta    720

tatggtgcag tttgtagagg agacctctta caaatgtgac tttattcaaa aaattacaaa    780

aacattgccg gatgctaaca ctgactttta ttatgaatgt aaacaagaaa gaataaaaga    840

atatgaaatg ttatttttgg tttcaaatga agaaatgcat aagcaaatac tgatgactat    900

aggtttggag aacctgtgtg aaaatccata ctttagcaat ctaaggcaaa acatgaaaga    960

ccttatccta cttttggcca cagtagcttc cagtgtgccg aactttaaac acttcggatt   1020

ttaccgtagc aatccagaac agattaatga aattcacaat caaagtttgc cacaggaaat   1080

tgcaaggcac tgcatggttc aggccaggtt attggcatat cgaactgagg atcataaaac   1140

aggagttggg gcagtcattt gggcagaagg gaaatctaga agttgtgatg gaacaggtgc   1200

catgtacttt gtaggatgtg gttacaatgc ttttcctgtt ggatctgagt atgctgactt   1260

cccacacatg gatgacaagc agaaagacag agaaataagg aaattcagat acatcataca   1320

tgcggaacag aatgccttga catttaggtg tcaagaaata aaaccagaag aaagaagcat   1380

gatttttgtg acaaagtgcc catgtgatga gtgtgtacct ttaattaaag gtgcaggcat   1440

aaaacaaatc tatgcaggag atgtagatgt tggaaaaaag aaggcagaca tctcttacat   1500

gaggttcggg gagcttgaag gtgttagcaa atttacgtgg cagctgaatc catcaggagc   1560

ttatggtctt gaacaaaatg agcctgaaag gagagaaaat ggtgtgttga gacctgtccc   1620

acagaaggaa gagcagcacc aggacaagaa gctgcgcctc ggaatccact aagaaggcct   1680

gtctacactg caggggaacc tcaagaactt ttcattgcac ttctaaaatt cagccttgtt   1740

cattcagaaa ataaggatgg attttgtgaa taattgaaaa gattttttaa ggaagctaat   1800

ttatttctag gatacaaatg gtgttaataa gaatatttgt cttttagatt tatgtgtggg   1860

ttttccataa tgtagtagtg tgttatttta ttacacgaaa tgagggagca ataacttcaa   1920

ccaatgtaat caccaacagg gactgatttc tatttatctt gactttatat tagccaattt   1980

gaaagggtct gcttcacaag aggtcatgcc tctgcaggga atcacacacc ttttgagaaa   2040

tattaattct tttgaattac aagagtgaca gttagtaaac tgctccaggg aaataagtgt   2100

catcttttaa gagtcagtgt atagcaaacc aaaagatcac atttataccc aaagctttct   2160

agtaatcaga atttacttaa ttagaattga ctcataaaaa taaagttagt ggactttgtc   2220

tccattttta aagtatattt tgtaaatgtt aattctgtgg tcctgtttat cacagacttt   2280

gggtagcaat aggaagagag tgttattctg agacagtgtc gctgcttgat atcactgact   2340

cttgaaatca ctaacagtga acctcaaatt tggttatgat gttaacagag aagaaatatt   2400

tgagtctgga atattgaaac tagctttcct agaattccat taataaatgc tgctccccca   2460

tatagtcttc ccttctgtat aattaacata ggttgtctca tggctttgat cttcaaaagg   2520

aagagccttt taaaaacatt tgccaacctc aagaataaat actgaaagtc ttgaaagtat   2580

ggtcatttca gctattccag attgctgtct gtgatttctc acatttttat ttgctgagaa   2640

acattcagaa aattattcca aaaatgaagg tacattttct gttctctcct aggttagaga   2700

ggggtggcct ggggtgcttc atgagaaatg tcttcctgga tctgcggtgg tcaggtttgc   2760

ctctgctttt gttccctgcc tttccgccac atcacacggc ctcactgggc ttcctaccag   2820

tttctcagaa ttacacgcac gaccatccaa acattggctc catgccaggg ctgtgactgc   2880

agcctgtgta ggaccatggg gagttcagag tcatcataca aggcagccaa gaactgccat   2940

aaacactaca cagatggagg gcatgggata ggacaggaga ggaggtgatg tacacttaga   3000

ggtaactaag gctagtttga aaaccgtgaa ttaagatatt cttatcagta taaaaacact   3060

gagattgctt acctcccaaa ttgctttatt gtattaactc tcatgcttca gctcttggat   3120

ttgttgtttc taactaacat gtcatgtaca ccaaacattt tataaatcaa tcagtaaata   3180

ttttgtaaga cccaaaatcc tggcatattg ccaggtctgt ggatttgcct gttgggtgtt   3240

gggatgggat atcagaggaa gaagcataca agtgggaaaa actgtgatta gaaagggaaa   3300

aataggcatt tccacagtac tattaagaga ggcatgataa tgccattttt tttcttctgt   3360

acaactggtc agatttcaat aaataatcat tgatggttta c                       3401


<210>  8289
<211>  514
<212>  PRT
<213>  Homo sapiens

<400>  8289

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Val Lys Arg Thr Gly Leu Val Val Val Lys Asn Met 
                85                  90                  95


Lys Ile Val Gly Leu His Cys Ser Ser Glu Asp Leu His Ala Gly Gln 
            100                 105                 110


Ile Ala Leu Ile Lys His Gly Ser Arg Leu Lys Asn Cys Asp Leu Tyr 
        115                 120                 125


Phe Ser Arg Lys Pro Cys Ser Ala Cys Leu Lys Met Ile Val Asn Ala 
    130                 135                 140


Gly Val Asn Arg Ile Ser Tyr Trp Pro Ala Asp Pro Glu Ile Ser Leu 
145                 150                 155                 160


Leu Thr Glu Ala Ser Ser Ser Glu Asp Ala Lys Leu Asp Ala Lys Ala 
                165                 170                 175


Val Glu Arg Leu Lys Ser Asn Ser Arg Ala His Val Cys Val Leu Leu 
            180                 185                 190


Gln Pro Leu Val Cys Tyr Met Val Gln Phe Val Glu Glu Thr Ser Tyr 
        195                 200                 205


Lys Cys Asp Phe Ile Gln Lys Ile Thr Lys Thr Leu Pro Asp Ala Asn 
    210                 215                 220


Thr Asp Phe Tyr Tyr Glu Cys Lys Gln Glu Arg Ile Lys Glu Tyr Glu 
225                 230                 235                 240


Met Leu Phe Leu Val Ser Asn Glu Glu Met His Lys Gln Ile Leu Met 
                245                 250                 255


Thr Ile Gly Leu Glu Asn Leu Cys Glu Asn Pro Tyr Phe Ser Asn Leu 
            260                 265                 270


Arg Gln Asn Met Lys Asp Leu Ile Leu Leu Leu Ala Thr Val Ala Ser 
        275                 280                 285


Ser Val Pro Asn Phe Lys His Phe Gly Phe Tyr Arg Ser Asn Pro Glu 
    290                 295                 300


Gln Ile Asn Glu Ile His Asn Gln Ser Leu Pro Gln Glu Ile Ala Arg 
305                 310                 315                 320


His Cys Met Val Gln Ala Arg Leu Leu Ala Tyr Arg Thr Glu Asp His 
                325                 330                 335


Lys Thr Gly Val Gly Ala Val Ile Trp Ala Glu Gly Lys Ser Arg Ser 
            340                 345                 350


Cys Asp Gly Thr Gly Ala Met Tyr Phe Val Gly Cys Gly Tyr Asn Ala 
        355                 360                 365


Phe Pro Val Gly Ser Glu Tyr Ala Asp Phe Pro His Met Asp Asp Lys 
    370                 375                 380


Gln Lys Asp Arg Glu Ile Arg Lys Phe Arg Tyr Ile Ile His Ala Glu 
385                 390                 395                 400


Gln Asn Ala Leu Thr Phe Arg Cys Gln Glu Ile Lys Pro Glu Glu Arg 
                405                 410                 415


Ser Met Ile Phe Val Thr Lys Cys Pro Cys Asp Glu Cys Val Pro Leu 
            420                 425                 430


Ile Lys Gly Ala Gly Ile Lys Gln Ile Tyr Ala Gly Asp Val Asp Val 
        435                 440                 445


Gly Lys Lys Lys Ala Asp Ile Ser Tyr Met Arg Phe Gly Glu Leu Glu 
    450                 455                 460


Gly Val Ser Lys Phe Thr Trp Gln Leu Asn Pro Ser Gly Ala Tyr Gly 
465                 470                 475                 480


Leu Glu Gln Asn Glu Pro Glu Arg Arg Glu Asn Gly Val Leu Arg Pro 
                485                 490                 495


Val Pro Gln Lys Glu Glu Gln His Gln Asp Lys Lys Leu Arg Leu Gly 
            500                 505                 510


Ile His 



<210>  8290
<211>  412
<212>  DNA
<213>  Homo sapiens

<400>  8290
gtgggccgtt gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga     60

tcatgtctga ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga    120

agctgggcag atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac    180

tggcagcatg accggtcaga taccaaggct ttctaaagtc aaccttttca ctctgctcag    240

cctctggatg gagctctttc cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga    300

gggaaagcat ggacccttag gagataatga agagaggacc agagtatcta ctgacaaaag    360

acaggattac tggaagcagc taagatgcct agatgaaagg tttaccatca ct            412


<210>  8291
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  8291

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Asp Tyr Trp Lys Gln Leu Arg Cys Leu Asp Glu Arg 
                85                  90                  95


Phe Thr Ile 



<210>  8292
<211>  822
<212>  DNA
<213>  Homo sapiens

<400>  8292
gtgggccgtt gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga     60

tcatgtctga ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga    120

agctgggcag atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac    180

tggcagcatg accggtcaga taccaaggct ttctaaagtc aaccttttca ctctgctcag    240

cctctggatg gagctctttc cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga    300

gggaaagcat ggacccttag gagataatga agagaggacc agagtatcta ctgacaaaag    360

acagaaaacc atgttctgct tgtttgaaaa tgattgtaaa tggattactg gaagcagcta    420

agatgcctag atgaaaggtt taccatcact gctggttagg aaatggatta tgagaactcg    480

aacagaggga aggtgaaatg caaccggagg aaacactctg atatgagctg gagttaaccg    540

aatttcatac tggcctgctg atccagaaat aagtttgctt acggaggctt ctagttctga    600

agatgcaaag ttagatgcca aagcagtgga aagattgaag tcaaacagtc gggcccatgt    660

gtgtgtctta cttcaacctt tggtgtgtta tatggtgcag tttgtagagg agacctctta    720

caaatgtgac tttattcaaa aaattacaaa aacattgccg gatgctaaca ctgactttta    780

ttatgaatgt aaacaagaaa gaataaaaga atatgaaatg tt                       822


<210>  8293
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  8293

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Lys Thr Met Phe Cys Leu Phe Glu Asn Asp Cys Lys 
                85                  90                  95


Trp Ile Thr Gly Ser Ser 
            100


<210>  8294
<211>  697
<212>  DNA
<213>  Homo sapiens

<400>  8294
gtgggccgtt gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga     60

tcatgtctga ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga    120

agctgggcag atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac    180

tggcagcatg accggtcaga taccaaggct ttctaaagtc aaccttttca ctctgctcag    240

cctctggatg gagctctttc cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga    300

gggaaagcat ggacccttag gagataatga agagaggacc agagtatcta ctgacaaaag    360

acagaaaacc atgttctgct tgtttgaaaa tgattgtaaa tgctggagtt aaccgaattt    420

catactggcc tgctgatcca gaaataagtt tgcttacgga ggcttctagt tctgaagatg    480

caaagttaga tgccaaagca gtggaaagat tgaagtcaaa cagtcgggcc catgtgtgtg    540

tcttacttca acctttggtg tgttatatgg tgcagtttgt agaggagacc tcttacaaat    600

gtgactttat tcaaaaaatt acaaaaacat tgccggatgc taacactgac ttttattatg    660

aatgtaaaca agaaagaata aaagaatatg aaatgtt                             697


<210>  8295
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  8295

Met Lys Arg Gly Pro Glu Tyr Leu Leu Thr Lys Asp Arg Lys Pro Cys 
1               5                   10                  15


Ser Ala Cys Leu Lys Met Ile Val Asn Ala Gly Val Asn Arg Ile Ser 
            20                  25                  30


Tyr Trp Pro Ala Asp Pro Glu Ile Ser Leu Leu Thr Glu Ala Ser Ser 
        35                  40                  45


Ser Glu Asp Ala Lys Leu Asp Ala Lys Ala Val Glu Arg Leu Lys Ser 
    50                  55                  60


Asn Ser Arg Ala His Val Cys Val Leu Leu Gln Pro Leu Val Cys Tyr 
65                  70                  75                  80


Met Val Gln Phe Val Glu Glu Thr Ser Tyr Lys Cys Asp Phe Ile Gln 
                85                  90                  95


Lys Ile Thr Lys Thr Leu Pro Asp Ala Asn Thr Asp Phe Tyr Tyr Glu 
            100                 105                 110


Cys Lys Gln Glu Arg Ile Lys Glu Tyr Glu 
        115                 120


<210>  8296
<211>  661
<212>  DNA
<213>  Homo sapiens

<400>  8296
gtgggccgtt gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga     60

tcatgtctga ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga    120

agctgggcag atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac    180

tggcagcatg accggtcaga taccaaggct ttctaaagtc aaccttttca ctctgctcag    240

cctctggatg gagctctttc cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga    300

gggaaagcat ggacccttag gagataatga agagaggacc agagtatcta ctgacaaaag    360

acagctggag ttaaccgaat ttcatactgg cctgctgatc cagaaataag tttgcttacg    420

gaggcttcta gttctgaaga tgcaaagtta gatgccaaag cagtggaaag attgaagtca    480

aacagtcggg cccatgtgtg tgtcttactt caacctttgg tgtgttatat ggtgcagttt    540

gtagaggaga cctcttacaa atgtgacttt attcaaaaaa ttacaaaaac attgccggat    600

gctaacactg acttttatta tgaatgtaaa caagaaagaa taaaagaata tgaaatgtta    660

t                                                                    661


<210>  8297
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  8297

Met Lys Glu Ala Gly Gln Met Gln Asn Leu Glu Ser Ala Arg Ala Gly 
1               5                   10                  15


Arg Ser Val Ser Thr Gln Thr Gly Ser Met Thr Gly Gln Ile Pro Arg 
            20                  25                  30


Leu Ser Lys Val Asn Leu Phe Thr Leu Leu Ser Leu Trp Met Glu Leu 
        35                  40                  45


Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn Glu Glu Gly 
    50                  55                  60


Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg Val Ser Thr 
65                  70                  75                  80


Asp Lys Arg Gln Leu Glu Leu Thr Glu Phe His Thr Gly Leu Leu Ile 
                85                  90                  95


Gln Lys 



<210>  8298
<211>  3418
<212>  DNA
<213>  Homo sapiens

<400>  8298
gtgggccgtt gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga     60

tcatgtctga ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga    120

agctgggcag atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac    180

tggcagcatg accggtcaga taccaaggct ttctaaagtc aaccttttca ctctgctcag    240

cctctggatg gagctctttc cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga    300

gggaaagcat ggacccttag gagataatga agagaggacc agagtatcta ctgacaaaag    360

acagaaaacc atgttctgct tgtttgaaaa tgattgtaaa tggattactg gaagcagcta    420

agatgcctag atgaaaggtt taccatcact gctggttagg aaatggatta tgagaactcg    480

aacagaggga aggtgaaatg caaccggagg aaacactctg atatgagctg gagttaaccg    540

aatttcatac tggcctgctg atccagaaat aagtttgctt acggaggctt ctagttctga    600

agatgcaaag ttagatgcca aagcagtgga aagattgaag tcaaacagtc gggcccatgt    660

gtgtgtctta cttcaacctt tggtgtgtta tatggtgcag tttgtagagg agacctctta    720

caaatgtgac tttattcaaa aaattacaaa aacattgccg gatgctaaca ctgactttta    780

ttatgaatgt aaacaagaaa gaataaaaga atatgaaatg ttatttttgg tttcaaatga    840

agaaatgcat aagcaaatac tgatgactat aggtttggag aacctgtgtg aaaatccata    900

ctttagcaat ctaaggcaaa acatgaaaga ccttatccta cttttggcca cagtagcttc    960

cagtgtgccg aactttaaac acttcggatt ttaccgtagc aatccagaac agattaatga   1020

aattcacaat caaagtttgc cacaggaaat tgcaaggcac tgcatggttc aggccaggtt   1080

attggcatat cgaactgaat tcagcagaac cctgcctgtg ttccagagta agagggcgat   1140

gtgaatctgc tattttactg gatcttagta cctcttgctt ctcatagaac accttatcat   1200

accagctgtg attccagtgt ttaaagacgc agatgtggtt acaatgcttt tcctgttgga   1260

tctgagtatg ctgacttccc acacatggat gacaagcaga aagacagaga aataaggaaa   1320

ttcagataca tcatacatgc ggaacagaat gccttgacat ttaggtgtca agaaataaaa   1380

ccagaagaaa gaagcatgat ttttgtgaca aagtgcccat gtgatgagtg tgtaccttta   1440

attaaaggtg caggcataaa acaaatctat gcaggagatg tagatgttgg aaaaaagaag   1500

gcagacatct cttacatgag gttcggggag cttgaaggtg ttagcaaatt tacgtggcag   1560

ctgaatccat caggagctta tggtcttgaa caaaatgagc ctgaaaggag agaaaatggt   1620

gtgttgagac ctgtcccaca gaaggaagag cagcaccagg acaagaagct gcgcctcgga   1680

atccactaag aaggcctgtc tacactgcag gggaacctca agaacttttc attgcacttc   1740

taaaattcag ccttgttcat tcagaaaata aggatggatt ttgtgaataa ttgaaaagat   1800

tttttaagga agctaattta tttctaggat acaaatggtg ttaataagaa tatttgtctt   1860

ttagatttat gtgtgggttt tccataatgt agtagtgtgt tattttatta cacgaaatga   1920

gggagcaata acttcaacca atgtaatcac caacagggac tgatttctat ttatcttgac   1980

tttatattag ccaatttgaa agggtctgct tcacaagagg tcatgcctct gcagggaatc   2040

acacaccttt tgagaaatat taattctttt gaattacaag agtgacagtt agtaaactgc   2100

tccagggaaa taagtgtcat cttttaagag tcagtgtata gcaaaccaaa agatcacatt   2160

tatacccaaa gctttctagt aatcagaatt tacttaatta gaattgactc ataaaaataa   2220

agttagtgga ctttgtctcc atttttaaag tatattttgt aaatgttaat tctgtggtcc   2280

tgtttatcac agactttggg tagcaatagg aagagagtgt tattctgaga cagtgtcgct   2340

gcttgatatc actgactctt gaaatcacta acagtgaacc tcaaatttgg ttatgatgtt   2400

aacagagaag aaatatttga gtctggaata ttgaaactag ctttcctaga attccattaa   2460

taaatgctgc tcccccatat agtcttccct tctgtataat taacataggt tgtctcatgg   2520

ctttgatctt caaaaggaag agccttttaa aaacatttgc caacctcaag aataaatact   2580

gaaagtcttg aaagtatggt catttcagct attccagatt gctgtctgtg atttctcaca   2640

tttttatttg ctgagaaaca ttcagaaaat tattccaaaa atgaaggtac attttctgtt   2700

ctctcctagg ttagagaggg gtggcctggg gtgcttcatg agaaatgtct tcctggatct   2760

gcggtggtca ggtttgcctc tgcttttgtt ccctgccttt ccgccacatc acacggcctc   2820

actgggcttc ctaccagttt ctcagaatta cacgcacgac catccaaaca ttggctccat   2880

gccagggctg tgactgcagc ctgtgtagga ccatggggag ttcagagtca tcatacaagg   2940

cagccaagaa ctgccataaa cactacacag atggagggca tgggatagga caggagagga   3000

ggtgatgtac acttagaggt aactaaggct agtttgaaaa ccgtgaatta agatattctt   3060

atcagtataa aaacactgag attgcttacc tcccaaattg ctttattgta ttaactctca   3120

tgcttcagct cttggatttg ttgtttctaa ctaacatgtc atgtacacca aacattttat   3180

aaatcaatca gtaaatattt tgtaagaccc aaaatcctgg catattgcca ggtctgtgga   3240

tttgcctgtt gggtgttggg atgggatatc agaggaagaa gcatacaagt gggaaaaact   3300

gtgattagaa agggaaaaat aggcatttcc acagtactat taagagaggc atgataatgc   3360

catttttttt cttctgtaca actggtcaga tttcaataaa taatcattga tggtttac     3418


<210>  8299
<211>  150
<212>  PRT
<213>  Homo sapiens

<400>  8299

Met Val Gln Phe Val Glu Glu Thr Ser Tyr Lys Cys Asp Phe Ile Gln 
1               5                   10                  15


Lys Ile Thr Lys Thr Leu Pro Asp Ala Asn Thr Asp Phe Tyr Tyr Glu 
            20                  25                  30


Cys Lys Gln Glu Arg Ile Lys Glu Tyr Glu Met Leu Phe Leu Val Ser 
        35                  40                  45


Asn Glu Glu Met His Lys Gln Ile Leu Met Thr Ile Gly Leu Glu Asn 
    50                  55                  60


Leu Cys Glu Asn Pro Tyr Phe Ser Asn Leu Arg Gln Asn Met Lys Asp 
65                  70                  75                  80


Leu Ile Leu Leu Leu Ala Thr Val Ala Ser Ser Val Pro Asn Phe Lys 
                85                  90                  95


His Phe Gly Phe Tyr Arg Ser Asn Pro Glu Gln Ile Asn Glu Ile His 
            100                 105                 110


Asn Gln Ser Leu Pro Gln Glu Ile Ala Arg His Cys Met Val Gln Ala 
        115                 120                 125


Arg Leu Leu Ala Tyr Arg Thr Glu Phe Ser Arg Thr Leu Pro Val Phe 
    130                 135                 140


Gln Ser Lys Arg Ala Met 
145                 150


<210>  8300
<211>  1177
<212>  DNA
<213>  Homo sapiens

<400>  8300
gccttacagt tgctgagagg aggcgagagg cgggggcgct agggccgaga tcatgtctga     60

ctgggagagg tttccttggc agcagaggac gctaggtttg ggatgaaaga agctgggcag    120

atgcaaaatc tggagagcgc gagggccggg cggtcagtca gcacccagac tggcagcatg    180

accggtgagt gtccgggacc ctgctcccgc caccctacct ttcgctctgc cctgtgcgtc    240

tcccgtcatt gaactccaga ttccttgtct gagcctcttt gcctcccctg ctgcttttgg    300

atgtctcctg cccgccctct gcgtgtcccc tccgcggtcg ccaggaccaa tcggctcggt    360

cgcactggct tttgaagtct cgctttttac ccctgttagc tacttctcac aggacctaga    420

gctggggcct ctgaggtcaa agagcctgaa catttccaaa cggcgctttt gccttgattt    480

ccaaattaac cgcacgtgac gctttcctgt atttcgactg ctttaccgtc gaaggtcaga    540

taccaaggct ttctaaagtc aaccttttca ctctgctcag cctctggatg gagctctttc    600

cagcagaagc ccagcggcaa aaatctcaga aaaatgaaga gggaaagcat ggacccttag    660

gagataatga agagaggacc agagtatcta ctgacaaaag acaggtaaag agaactggtc    720

ttgtggtggt gaaaaacatg aaaattgttg gtctccactg ttctagtgaa gatttacatg    780

ccgggcagat tgctcttatt aaacatgggt caaggctgaa aaactgtgat ctttattttt    840

ccagaaaacc atgttctgct tgtttgaaaa tgattgtaaa tgctggagtt aaccgaattt    900

catactggcc tgctgatcca gaaataagtt tgcttacgga ggcttctagt tctgaagatg    960

caaagttaga tgccaaagca gtggaaagat tgaagtcaaa cagtcgggcc catgtgtgtg   1020

tcttacttca acctttggtg tgttatatgg tgcagtttgt agaggagacc tcttacaaat   1080

gtgactttat tcaaaaaatt acaaaaacat tgccggatgc taacactgac ttttattatg   1140

aatgtaaaca agaaagaata aaagaatatg aaatgtt                            1177


<210>  8301
<211>  195
<212>  PRT
<213>  Homo sapiens

<400>  8301

Met Glu Leu Phe Pro Ala Glu Ala Gln Arg Gln Lys Ser Gln Lys Asn 
1               5                   10                  15


Glu Glu Gly Lys His Gly Pro Leu Gly Asp Asn Glu Glu Arg Thr Arg 
            20                  25                  30


Val Ser Thr Asp Lys Arg Gln Val Lys Arg Thr Gly Leu Val Val Val 
        35                  40                  45


Lys Asn Met Lys Ile Val Gly Leu His Cys Ser Ser Glu Asp Leu His 
    50                  55                  60


Ala Gly Gln Ile Ala Leu Ile Lys His Gly Ser Arg Leu Lys Asn Cys 
65                  70                  75                  80


Asp Leu Tyr Phe Ser Arg Lys Pro Cys Ser Ala Cys Leu Lys Met Ile 
                85                  90                  95


Val Asn Ala Gly Val Asn Arg Ile Ser Tyr Trp Pro Ala Asp Pro Glu 
            100                 105                 110


Ile Ser Leu Leu Thr Glu Ala Ser Ser Ser Glu Asp Ala Lys Leu Asp 
        115                 120                 125


Ala Lys Ala Val Glu Arg Leu Lys Ser Asn Ser Arg Ala His Val Cys 
    130                 135                 140


Val Leu Leu Gln Pro Leu Val Cys Tyr Met Val Gln Phe Val Glu Glu 
145                 150                 155                 160


Thr Ser Tyr Lys Cys Asp Phe Ile Gln Lys Ile Thr Lys Thr Leu Pro 
                165                 170                 175


Asp Ala Asn Thr Asp Phe Tyr Tyr Glu Cys Lys Gln Glu Arg Ile Lys 
            180                 185                 190


Glu Tyr Glu 
        195


<210>  8302
<211>  684
<212>  DNA
<213>  Homo sapiens

<400>  8302
ataccatttc tgtataaagt tcaaaaagac ataccatata ttggttaaat gtggtaggcc     60

aggcatggtg ctcacaccta taatcccagc atattgggag actgaagcgg gccaattgct    120

tgagcccagg agttcaagac cagcctgggc atcacagcaa aacccatctc tacaaatatt    180

acaaatcaaa aagtaaatta aaaaaattca tcaagctata cactttatgt ttagtttatt    240

gcatacttta aacatgtatc atttattgta caaataaagc tattaaacac aaaagccagg    300

aagaggttga agccatactc ttttcccagc ctgcccagtc agataagtcc gtcttccttc    360

cagtccccag attctcccta ccccacacac agtccccttc tcccttagga ggtacatttt    420

atttcttcca gtctagtaat aggacgtccc cccaccaaaa acataaaaca aaaagtttta    480

tgaattactt gccgtacact gttgagtgaa ttcagttttt ggtttttttt ttttttgaga    540

cagggtctcg ctgtgtcacc caggctggaa tgcagtggca cagtcatggc tcactgcaga    600

cttggcctct ctgggctcaa acagtcctcc cacctcaggc tcctgagtag ctgggattac    660

aggtgtgcgc cacaacacct gttt                                           684


<210>  8303
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  8303

Met Val Leu Thr Pro Ile Ile Pro Ala Tyr Trp Glu Thr Glu Ala Gly 
1               5                   10                  15


Gln Leu Leu Glu Pro Arg Ser Ser Arg Pro Ala Trp Ala Ser Gln Gln 
            20                  25                  30


Asn Pro Ser Leu Gln Ile Leu Gln Ile Lys Lys 
        35                  40


<210>  8304
<211>  2911
<212>  DNA
<213>  Homo sapiens

<400>  8304
gagtatatct aagtgtttca gaatacactc aaattccaga atacgtctgc aatagtgcca     60

ggcacatagt agatcttcag tggatattga atgaatcgtg acaaatgata tgaagcccca    120

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    180

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca    240

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg    300

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg    360

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc    420

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa    480

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt    540

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa    600

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag    660

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc    720

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag    780

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc    840

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat    900

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag    960

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1020

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1080

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1140

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1200

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   1260

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   1320

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   1380

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   1440

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   1500

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   1560

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   1620

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   1680

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   1740

tatcagatgt tgataaaagc aatttttttc taataagctg tcattctata attgcccatc   1800

acagtcttta gtgaacacat agaaagccta tacagttttg gtcctgaata gtctcttgtg   1860

actaggatga ttgaggtgtt aattcctctt ccttataaaa aggcttggaa tcaaaaatat   1920

tttaaaaggc cgtggtttcg tttcagacat caaccatcta aaacgggatt ttaaagcgat   1980

attttacaag aatgaaaggc acaattgttg atctgtattt tttacacttc agtttctaaa   2040

tcatgaatcg ttgccttcca caggaaccct cccttataca ttacttgagt gttgtgtagt   2100

ttttcttcag ccaggtattt ctctgcctag agaggggaag agaaatgtgt tctccaggac   2160

tgatcccctt tgtagatttt gtacctgaag agttacctgg cagggcacca cccttggcta   2220

ggcccaggtg tgtgtttctt tcttgcctgg catggacccc gaggcaggtg atgtggggcc   2280

tggcgcacct ccccgctttg gcagctgtgg cctccctggc cagtgccctt gcaggaggcc   2340

ggccggcagc ctgatgaccc gtactcttta gtcactgacg tcagattatt tttataacgt   2400

tccctgacag ttcagagtcc cttcgaattg cacttttctg gtttcgctta tttaattaaa   2460

agagatgagt gtaagtataa aaaatgaagg tgaaataacc attggaattg tatttggtta   2520

cttaatactg ttccacaaca tcttgggacg tctgttttcc tttggagagt gaggccttgt   2580

tattattctt ttctgataaa gaaaacattt tatttccttt gggcttgcat tagctctttc   2640

ctagcaaccc attatcccag ctcagtacct ttcaaacaga aaactagagt ctggggtttt   2700

gttgtgatct gaatttgtaa gttattaatg tgaaaggggg agcaggaagc tccccctttg   2760

cacaaagggg gatttgtttg cacaaagttc actgtaaata ctgtgagaat tgaattctga   2820

aaaggtcata tttagtgatt tcaaaagcac acatttaaat gaagactgac taaataaaag   2880

gtaccacaca cttcttggtt ggtttcattc c                                  2911


<210>  8305
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  8305

Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
1               5                   10                  15


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
            20                  25                  30


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
        35                  40                  45


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
    50                  55                  60


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
65                  70                  75                  80


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
                85                  90                  95


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
            100                 105                 110


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
        115                 120                 125


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
    130                 135                 140


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
145                 150                 155                 160


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
                165                 170                 175


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
            180                 185                 190


Pro 



<210>  8306
<211>  3697
<212>  DNA
<213>  Homo sapiens

<400>  8306
gtgacgttac aggactgagg agggaggaag taaaagggag ctgtgactgt ggtacgtatc     60

tgaaagcaag tgttagagag ggagtggaga acgcataagc aagctggttt gaccagaaac    120

agaactgcct gtgacagatt aagagacaag caaggcttgg aatctgagag caagcaaaga    180

gagtggaaat ttacagctgc cctatgtgag tgttcaagtg atcattttct ggtaacgttt    240

tccagtggta actgttactc ttcaaaaaga gggacagaaa gtcaagacct aattgtggaa    300

actcttttct ctgccacgct tggtaatagg aggcaacctc tattaaatgg acgataaagg    360

ctacttcatc taaagtgctt tgagctcaag aaagagctgt cttcagcacc tcaccatgtg    420

tctacatttt gttgcttaga aaagcctagg catttctgta acatttgcat tccatattgg    480

aagaagagat ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca    540

gcagaaattg tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag    600

acagacaagg cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt    660

ggtacaaacg agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac    720

agcagtggcc tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa    780

aaagatgtga cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct    840

actgtggagt atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa    900

gccccacaga ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca    960

cttgccaaaa tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg   1020

tcaacatttg atattgcttc agatgccttt gctactttca aggatttact aaccagacat   1080

aaagtgttgg tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag   1140

aaattgcttc agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag   1200

ctgatcctgg accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac   1260

ctgaaactca tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt   1320

catgttttta aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg   1380

ttaaaaaatc agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat   1440

gatgagcagt tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa   1500

acggcccctt gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt   1560

gtacagtgtg tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt   1620

ttctgctgta attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc   1680

tagaataata tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg   1740

tatcagatgt tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc   1800

cgctaaatgg gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca   1860

ggggagaact gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac   1920

acagatcgct cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt   1980

gtgtcctttg ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga   2040

tccagtgctc cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct   2100

cctcagcatg gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc   2160

aactgagcag gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg   2220

tgacctgctt gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat   2280

attagcttcc agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa   2340

tgctttctgc tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc   2400

acaaaccatg ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg   2460

aaggagaaat gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag   2520

ccattgtatc agatgttgat aaaagcaatt tttttctaat aagctgtcat tctataattg   2580

cccatcacag tctttagtga acacatagaa agcctataca gttttggtcc tgaatagtct   2640

cttgtgacta ggatgattga ggtgttaatt cctcttcctt ataaaaaggc ttggaatcaa   2700

aaatatttta aaaggccgtg gtttcgtttc agacatcaac catctaaaac gggattttaa   2760

agcgatattt tacaagaatg aaaggcacaa ttgttgatct gtatttttta cacttcagtt   2820

tctaaatcat gaatcgttgc cttccacagg aaccctccct tatacattac ttgagtgttg   2880

tgtagttttt cttcagccag gtatttctct gcctagagag gggaagagaa atgtgttctc   2940

caggactgat cccctttgta gattttgtac ctgaagagtt acctggcagg gcaccaccct   3000

tggctaggcc caggtgtgtg tttctttctt gcctggcatg gaccccgagg caggtgatgt   3060

ggggcctggc gcacctcccc gctttggcag ctgtggcctc cctggccagt gcccttgcag   3120

gaggccggcc ggcagcctga tgacccgtac tctttagtca ctgacgtcag attattttta   3180

taacgttccc tgacagttca gagtcccttc gaattgcact tttctggttt cgcttattta   3240

attaaaagag atgagtgtaa gtataaaaaa tgaaggtgaa ataaccattg gaattgtatt   3300

tggttactta atactgttcc acaacatctt gggacgtctg ttttcctttg gagagtgagg   3360

ccttgttatt attcttttct gataaagaaa acattttatt tcctttgggc ttgcattagc   3420

tctttcctag caacccatta tcccagctca gtacctttca aacagaaaac tagagtctgg   3480

ggttttgttg tgatctgaat ttgtaagtta ttaatgtgaa agggggagca ggaagctccc   3540

cctttgcaca aagggggatt tgtttgcaca aagttcactg taaatactgt gagaattgaa   3600

ttctgaaaag gtcatattta gtgatttcaa aagcacacat ttaaatgaag actgactaaa   3660

taaaaggtac cacacacttc ttggttggtt tcattcc                            3697


<210>  8307
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8307

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8308
<211>  3691
<212>  DNA
<213>  Homo sapiens

<400>  8308
gagaacctag tatcacacta ggcttctgaa aacaccaatc aagagttgct taatgcaggg     60

gtcccttacc cctgggctgc agacctgtac ctgtccatgg cctgttagga accgggcagc    120

acagtaggag gactgaggag ggaggaagta aaagggagct gtgactgtgg tacgtatctg    180

aaagcaagtg ttagagaggg agtggagaac gcataagcaa gctggtttga ccagaaacag    240

aactgcctgt gacagattaa gagacaagca aggcttggaa tctgagagca agcaaagaga    300

gtggaaattt acagctgccc tatgaggcaa cctctattaa atggacgata aaggctactt    360

catctaaagt gctttgagct caagaaagag ctgtcttcag cacctcacca tgtgtctaca    420

ttttgttgct tagaaaagcc taggcatttc tgtaacattt gcattccata ttggaagaag    480

agatttctac acatgaaaaa aatgcctttg tttagtaaat cacacaaaaa tccagcagaa    540

attgtgaaaa tcctgaaaga caatttggcc attttggaaa agcaagacaa aaagacagac    600

aaggcttcag aagaagtgtc taaatcactg caagcaatga aagaaattct gtgtggtaca    660

aacgagaaag aacccccaac agaagcagtg gctcagctag cacaagaact ctacagcagt    720

ggcctgctag tgacactgat agctgacctg cagctgatag actttgaggg aaaaaaagat    780

gtgacccaga tatttaacaa catcttgaga agacagatag gcactcggag tcctactgtg    840

gagtatatta gtgctcatcc tcatatcctg tttatgctcc tcaaaggata tgaagcccca    900

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    960

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca   1020

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg   1080

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg   1140

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc   1200

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa   1260

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt   1320

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa   1380

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag   1440

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc   1500

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag   1560

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc   1620

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat   1680

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag   1740

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1800

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1860

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1920

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1980

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   2040

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   2100

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   2160

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   2220

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   2280

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   2340

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   2400

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   2460

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   2520

tatcagatgt tgataaaagc aatttttttc taataagctg tcattctata attgcccatc   2580

acagtcttta gtgaacacat agaaagccta tacagttttg gtcctgaata gtctcttgtg   2640

actaggatga ttgaggtgtt aattcctctt ccttataaaa aggcttggaa tcaaaaatat   2700

tttaaaaggc cgtggtttcg tttcagacat caaccatcta aaacgggatt ttaaagcgat   2760

attttacaag aatgaaaggc acaattgttg atctgtattt tttacacttc agtttctaaa   2820

tcatgaatcg ttgccttcca caggaaccct cccttataca ttacttgagt gttgtgtagt   2880

ttttcttcag ccaggtattt ctctgcctag agaggggaag agaaatgtgt tctccaggac   2940

tgatcccctt tgtagatttt gtacctgaag agttacctgg cagggcacca cccttggcta   3000

ggcccaggtg tgtgtttctt tcttgcctgg catggacccc gaggcaggtg atgtggggcc   3060

tggcgcacct ccccgctttg gcagctgtgg cctccctggc cagtgccctt gcaggaggcc   3120

ggccggcagc ctgatgaccc gtactcttta gtcactgacg tcagattatt tttataacgt   3180

tccctgacag ttcagagtcc cttcgaattg cacttttctg gtttcgctta tttaattaaa   3240

agagatgagt gtaagtataa aaaatgaagg tgaaataacc attggaattg tatttggtta   3300

cttaatactg ttccacaaca tcttgggacg tctgttttcc tttggagagt gaggccttgt   3360

tattattctt ttctgataaa gaaaacattt tatttccttt gggcttgcat tagctctttc   3420

ctagcaaccc attatcccag ctcagtacct ttcaaacaga aaactagagt ctggggtttt   3480

gttgtgatct gaatttgtaa gttattaatg tgaaaggggg agcaggaagc tccccctttg   3540

cacaaagggg gatttgtttg cacaaagttc actgtaaata ctgtgagaat tgaattctga   3600

aaaggtcata tttagtgatt tcaaaagcac acatttaaat gaagactgac taaataaaag   3660

gtaccacaca cttcttggtt ggtttcattc c                                  3691


<210>  8309
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8309

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8310
<211>  3447
<212>  DNA
<213>  Homo sapiens

<400>  8310
agcgttttgt tagggaagaa gtggagaaca gatattggaa ggcaattagc tgtctctaat     60

acattgataa aatatataac tataactgca aaatgctaat aacccagcag aggagtagat    120

ttgggaacat aagatgaaaa agtcaacaag tgcattgatc acaacatatg gtaatgatag    180

cgtgattgtg atgacctttg ttttatacct ccttttacat tccatattgg aagaagagat    240

ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca gcagaaattg    300

tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag acagacaagg    360

cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt ggtacaaacg    420

agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac agcagtggcc    480

tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa aaagatgtga    540

cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct actgtggagt    600

atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa gccccacaga    660

ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca cttgccaaaa    720

tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg tcaacatttg    780

atattgcttc agatgccttt gctactttca aggatttact aaccagacat aaagtgttgg    840

tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag aaattgcttc    900

agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag ctgatcctgg    960

accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac ctgaaactca   1020

tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt catgttttta   1080

aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg ttaaaaaatc   1140

agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat gatgagcagt   1200

tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa acggcccctt   1260

gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt gtacagtgtg   1320

tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt ttctgctgta   1380

attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc tagaataata   1440

tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg tatcagatgt   1500

tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc cgctaaatgg   1560

gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca ggggagaact   1620

gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac acagatcgct   1680

cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt gtgtcctttg   1740

ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga tccagtgctc   1800

cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct cctcagcatg   1860

gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc aactgagcag   1920

gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg tgacctgctt   1980

gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat attagcttcc   2040

agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa tgctttctgc   2100

tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc acaaaccatg   2160

ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg aaggagaaat   2220

gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag ccattgtatc   2280

agatgttgat aaaagcaatt tttttctaat aagctgtcat tctataattg cccatcacag   2340

tctttagtga acacatagaa agcctataca gttttggtcc tgaatagtct cttgtgacta   2400

ggatgattga ggtgttaatt cctcttcctt ataaaaaggc ttggaatcaa aaatatttta   2460

aaaggccgtg gtttcgtttc agacatcaac catctaaaac gggattttaa agcgatattt   2520

tacaagaatg aaaggcacaa ttgttgatct gtatttttta cacttcagtt tctaaatcat   2580

gaatcgttgc cttccacagg aaccctccct tatacattac ttgagtgttg tgtagttttt   2640

cttcagccag gtatttctct gcctagagag gggaagagaa atgtgttctc caggactgat   2700

cccctttgta gattttgtac ctgaagagtt acctggcagg gcaccaccct tggctaggcc   2760

caggtgtgtg tttctttctt gcctggcatg gaccccgagg caggtgatgt ggggcctggc   2820

gcacctcccc gctttggcag ctgtggcctc cctggccagt gcccttgcag gaggccggcc   2880

ggcagcctga tgacccgtac tctttagtca ctgacgtcag attattttta taacgttccc   2940

tgacagttca gagtcccttc gaattgcact tttctggttt cgcttattta attaaaagag   3000

atgagtgtaa gtataaaaaa tgaaggtgaa ataaccattg gaattgtatt tggttactta   3060

atactgttcc acaacatctt gggacgtctg ttttcctttg gagagtgagg ccttgttatt   3120

attcttttct gataaagaaa acattttatt tcctttgggc ttgcattagc tctttcctag   3180

caacccatta tcccagctca gtacctttca aacagaaaac tagagtctgg ggttttgttg   3240

tgatctgaat ttgtaagtta ttaatgtgaa agggggagca ggaagctccc cctttgcaca   3300

aagggggatt tgtttgcaca aagttcactg taaatactgt gagaattgaa ttctgaaaag   3360

gtcatattta gtgatttcaa aagcacacat ttaaatgaag actgactaaa taaaaggtac   3420

cacacacttc ttggttggtt tcattcc                                       3447


<210>  8311
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8311

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8312
<211>  3805
<212>  DNA
<213>  Homo sapiens

<400>  8312
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaagcattc catattggaa gaagagattt    600

ctacacatga aaaaaatgcc tttgtttagt aaatcacaca aaaatccagc agaaattgtg    660

aaaatcctga aagacaattt ggccattttg gaaaagcaag acaaaaagac agacaaggct    720

tcagaagaag tgtctaaatc actgcaagca atgaaagaaa ttctgtgtgg tacaaacgag    780

aaagaacccc caacagaagc agtggctcag ctagcacaag aactctacag cagtggcctg    840

ctagtgacac tgatagctga cctgcagctg atagactttg agggaaaaaa agatgtgacc    900

cagatattta acaacatctt gagaagacag ataggcactc ggagtcctac tgtggagtat    960

attagtgctc atcctcatat cctgtttatg ctcctcaaag gatatgaagc cccacagatt   1020

gccttacgtt gtgggattat gctgagagaa tgtattcgac atgaaccact tgccaaaatc   1080

atcctctttt ctaatcaatt cagagatttc tttaagtacg tggagttgtc aacatttgat   1140

attgcttcag atgcctttgc tactttcaag gatttactaa ccagacataa agtgttggta   1200

gcagacttct tagaacaaaa ttacgacact atttttgaag actatgagaa attgcttcag   1260

tctgagaatt atgttactaa gagacagtct ttaaagctgc taggggagct gatcctggac   1320

cgtcacaact ttgccatcat gacaaagtat atcagcaagc cggagaacct gaaactcatg   1380

atgaacctcc ttcgggataa aagtcccaac atccagtttg aagcctttca tgtttttaag   1440

gtgtttgtgg ccagtcctca caaaacacag cctattgtgg agatcctgtt aaaaaatcag   1500

cccaaactca ttgagtttct gagcagcttc caaaaagaaa ggacggatga tgagcagttc   1560

gctgacgaga agaactactt gattaaacag atccgagact tgaagaaaac ggccccttga   1620

agagctcccc ggcccctgtc acagtcagtc gtctcatttg tccagtttgt acagtgtgtc   1680

atttcagaaa gtcatcattc ttgggaagac tttggaggtg cctatttttt ctgctgtaat   1740

tgttctgggt agatggagta taaacatttg aatggaaaaa aattaaccta gaataatata   1800

ttcattttag tcaagtctgt gattatttat gtgaaatgag aaccattgta tcagatgttg   1860

ataaaagcaa ttttaacttg cagatgtgag cccctgggca caatgagccg ctaaatggga   1920

gctcaattga caggcatcac caagtcttca aggaggactg agttctcagg ggagaactgg   1980

gaatggggcc agggtgcaaa aatgctttgc ccatctgtag gtagacacac agatcgctca   2040

gggcactgag agatcccaga aggtaacgtt aatgttttca gtcattgtgt gtcctttgtt   2100

gctgccaatg tctttggact gtaatcagtg catccacacc tcccaggatc cagtgctccc   2160

tctcagctca gtctcccctc tctccctgtc ctgcattcca tcccagctcc tcagcatggc   2220

ctcagtgggc gcacccatgc ctcccgcagt ccaggtgagc aggggagcaa ctgagcagga   2280

agaggatgga tcaacaaggg tcacggggaa taggggaccc acggggtgtg acctgcttgc   2340

tagagaactg tgaacatgtg gctctggata gagtgactgc tgctccatat tagcttccag   2400

agggtgagtg agggacagaa tatttccttc ataatggtca tgggtgaatg ctttctgctg   2460

taagtgtctt ttagagtagg aatcagcata gtgggatgcc cagcaggcac aaaccatggg   2520

tccagggagt ctcagcgggg aacttctatc agtatcaata accattggaa ggagaaatga   2580

ttcatgtgtg aaaaaattct cagatccatc aataaatttt tttcagagcc attgtatcag   2640

atgttgataa aagcaatttt tttctaataa gctgtcattc tataattgcc catcacagtc   2700

tttagtgaac acatagaaag cctatacagt tttggtcctg aatagtctct tgtgactagg   2760

atgattgagg tgttaattcc tcttccttat aaaaaggctt ggaatcaaaa atattttaaa   2820

aggccgtggt ttcgtttcag acatcaacca tctaaaacgg gattttaaag cgatatttta   2880

caagaatgaa aggcacaatt gttgatctgt attttttaca cttcagtttc taaatcatga   2940

atcgttgcct tccacaggaa ccctccctta tacattactt gagtgttgtg tagtttttct   3000

tcagccaggt atttctctgc ctagagaggg gaagagaaat gtgttctcca ggactgatcc   3060

cctttgtaga ttttgtacct gaagagttac ctggcagggc accacccttg gctaggccca   3120

ggtgtgtgtt tctttcttgc ctggcatgga ccccgaggca ggtgatgtgg ggcctggcgc   3180

acctccccgc tttggcagct gtggcctccc tggccagtgc ccttgcagga ggccggccgg   3240

cagcctgatg acccgtactc tttagtcact gacgtcagat tatttttata acgttccctg   3300

acagttcaga gtcccttcga attgcacttt tctggtttcg cttatttaat taaaagagat   3360

gagtgtaagt ataaaaaatg aaggtgaaat aaccattgga attgtatttg gttacttaat   3420

actgttccac aacatcttgg gacgtctgtt ttcctttgga gagtgaggcc ttgttattat   3480

tcttttctga taaagaaaac attttatttc ctttgggctt gcattagctc tttcctagca   3540

acccattatc ccagctcagt acctttcaaa cagaaaacta gagtctgggg ttttgttgtg   3600

atctgaattt gtaagttatt aatgtgaaag ggggagcagg aagctccccc tttgcacaaa   3660

gggggatttg tttgcacaaa gttcactgta aatactgtga gaattgaatt ctgaaaaggt   3720

catatttagt gatttcaaaa gcacacattt aaatgaagac tgactaaata aaaggtacca   3780

cacacttctt ggttggtttc attcc                                         3805


<210>  8313
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8313

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8314
<211>  4194
<212>  DNA
<213>  Homo sapiens

<400>  8314
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaaggcaaa tctttcatct gcagttttga    600

ctctatccca atggagaaat tgttaatctt ttagtaagca ttaagaattg tatagaaaat    660

gcagaatttg tttggaagaa aagcatggat aattcatttg tgatgaatgt tgactccaca    720

aagggtttgt tcaagtattt ggagacggtt gttaaattgc cttttaagga ggactgagga    780

gggaggaagt aaaagggagc tgtgactgtg gtacgtatct gaaagcaagt gttagagagg    840

gagtggagaa cgcataagca agctggtttg accagaaaca gaactgcctg tgacagatta    900

agagacaagc aaggcttgga atctgagagc aagcaaagag agtggaaatt tacagctgcc    960

ctatcattcc atattggaag aagagatttc tacacatgaa aaaaatgcct ttgtttagta   1020

aatcacacaa aaatccagca gaaattgtga aaatcctgaa agacaatttg gccattttgg   1080

aaaagcaaga caaaaagaca gacaaggctt cagaagaagt gtctaaatca ctgcaagcaa   1140

tgaaagaaat tctgtgtggt acaaacgaga aagaaccccc aacagaagca gtggctcagc   1200

tagcacaaga actctacagc agtggcctgc tagtgacact gatagctgac ctgcagctga   1260

tagactttga gggaaaaaaa gatgtgaccc agatatttaa caacatcttg agaagacaga   1320

taggcactcg gagtcctact gtggagtata ttagtgctca tcctcatatc ctgtttatgc   1380

tcctcaaagg atatgaagcc ccacagattg ccttacgttg tgggattatg ctgagagaat   1440

gtattcgaca tgaaccactt gccaaaatca tcctcttttc taatcaattc agagatttct   1500

ttaagtacgt ggagttgtca acatttgata ttgcttcaga tgcctttgct actttcaagg   1560

atttactaac cagacataaa gtgttggtag cagacttctt agaacaaaat tacgacacta   1620

tttttgaaga ctatgagaaa ttgcttcagt ctgagaatta tgttactaag agacagtctt   1680

taaagctgct aggggagctg atcctggacc gtcacaactt tgccatcatg acaaagtata   1740

tcagcaagcc ggagaacctg aaactcatga tgaacctcct tcgggataaa agtcccaaca   1800

tccagtttga agcctttcat gtttttaagg tgtttgtggc cagtcctcac aaaacacagc   1860

ctattgtgga gatcctgtta aaaaatcagc ccaaactcat tgagtttctg agcagcttcc   1920

aaaaagaaag gacggatgat gagcagttcg ctgacgagaa gaactacttg attaaacaga   1980

tccgagactt gaagaaaacg gccccttgaa gagctccccg gcccctgtca cagtcagtcg   2040

tctcatttgt ccagtttgta cagtgtgtca tttcagaaag tcatcattct tgggaagact   2100

ttggaggtgc ctattttttc tgctgtaatt gttctgggta gatggagtat aaacatttga   2160

atggaaaaaa attaacctag aataatatat tcattttagt caagtctgtg attatttatg   2220

tgaaatgaga accattgtat cagatgttga taaaagcaat tttaacttgc agatgtgagc   2280

ccctgggcac aatgagccgc taaatgggag ctcaattgac aggcatcacc aagtcttcaa   2340

ggaggactga gttctcaggg gagaactggg aatggggcca gggtgcaaaa atgctttgcc   2400

catctgtagg tagacacaca gatcgctcag ggcactgaga gatcccagaa ggtaacgtta   2460

atgttttcag tcattgtgtg tcctttgttg ctgccaatgt ctttggactg taatcagtgc   2520

atccacacct cccaggatcc agtgctccct ctcagctcag tctcccctct ctccctgtcc   2580

tgcattccat cccagctcct cagcatggcc tcagtgggcg cacccatgcc tcccgcagtc   2640

caggtgagca ggggagcaac tgagcaggaa gaggatggat caacaagggt cacggggaat   2700

aggggaccca cggggtgtga cctgcttgct agagaactgt gaacatgtgg ctctggatag   2760

agtgactgct gctccatatt agcttccaga gggtgagtga gggacagaat atttccttca   2820

taatggtcat gggtgaatgc tttctgctgt aagtgtcttt tagagtagga atcagcatag   2880

tgggatgccc agcaggcaca aaccatgggt ccagggagtc tcagcgggga acttctatca   2940

gtatcaataa ccattggaag gagaaatgat tcatgtgtga aaaaattctc agatccatca   3000

ataaattttt ttcagagcca ttgtatcaga tgttgataaa agcaattttt ttctaataag   3060

ctgtcattct ataattgccc atcacagtct ttagtgaaca catagaaagc ctatacagtt   3120

ttggtcctga atagtctctt gtgactagga tgattgaggt gttaattcct cttccttata   3180

aaaaggcttg gaatcaaaaa tattttaaaa ggccgtggtt tcgtttcaga catcaaccat   3240

ctaaaacggg attttaaagc gatattttac aagaatgaaa ggcacaattg ttgatctgta   3300

ttttttacac ttcagtttct aaatcatgaa tcgttgcctt ccacaggaac cctcccttat   3360

acattacttg agtgttgtgt agtttttctt cagccaggta tttctctgcc tagagagggg   3420

aagagaaatg tgttctccag gactgatccc ctttgtagat tttgtacctg aagagttacc   3480

tggcagggca ccacccttgg ctaggcccag gtgtgtgttt ctttcttgcc tggcatggac   3540

cccgaggcag gtgatgtggg gcctggcgca cctccccgct ttggcagctg tggcctccct   3600

ggccagtgcc cttgcaggag gccggccggc agcctgatga cccgtactct ttagtcactg   3660

acgtcagatt atttttataa cgttccctga cagttcagag tcccttcgaa ttgcactttt   3720

ctggtttcgc ttatttaatt aaaagagatg agtgtaagta taaaaaatga aggtgaaata   3780

accattggaa ttgtatttgg ttacttaata ctgttccaca acatcttggg acgtctgttt   3840

tcctttggag agtgaggcct tgttattatt cttttctgat aaagaaaaca ttttatttcc   3900

tttgggcttg cattagctct ttcctagcaa cccattatcc cagctcagta cctttcaaac   3960

agaaaactag agtctggggt tttgttgtga tctgaatttg taagttatta atgtgaaagg   4020

gggagcagga agctccccct ttgcacaaag ggggatttgt ttgcacaaag ttcactgtaa   4080

atactgtgag aattgaattc tgaaaaggtc atatttagtg atttcaaaag cacacattta   4140

aatgaagact gactaaataa aaggtaccac acacttcttg gttggtttca ttcc         4194


<210>  8315
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8315

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8316
<211>  2893
<212>  DNA
<213>  Homo sapiens

<400>  8316
gagtatatct aagtgtttca gaatacactc aaattccaga atacgtctgc aatagtgcca     60

ggcacatagt agatcttcag tggatattga atgaatcgtg acaaatgata tgaagcccca    120

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    180

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca    240

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg    300

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg    360

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc    420

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa    480

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt    540

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa    600

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag    660

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc    720

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag    780

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc    840

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat    900

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag    960

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1020

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1080

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1140

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1200

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   1260

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   1320

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   1380

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   1440

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   1500

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   1560

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   1620

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   1680

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   1740

tatcagatgt tgataaaagc aatttttttc taataagctg tcattctata attgcccatc   1800

acagtcttta gtgaacacat agaaagccta tacagttttg gtcctgaata gtctcttgtg   1860

actaggatga ttgaggtgtt aattcctctt ccttataaaa aggcttggaa tcaaaaatat   1920

tttaaaaggc cgtggtttcg tttcagacat caaccatcta aaacgggatt ttaaagcgat   1980

attttacaag aatgaaaggc acaattgttg atctgtattt tttacacttc agtttctaaa   2040

tcatgaatcg ttgccttcca caggaaccct cccttataca ttacttgagt gttgtgtagt   2100

ttttcttcag ccaggtattt ctctgcctag agaggggaag agaaatgtgt tctccaggac   2160

tgatcccctt tgtagatttt gtacctgaag agttacctgg cagggcacca cccttggcta   2220

ggcccaggtg tgtgtttctt tcttgcctgg catggacccc gaggcaggtg atgtggggcc   2280

tggcgcacct ccccgctttg gcagctgtgg cctccctggc cagtgccctt gcaggaggcc   2340

ggccggcagc ctgatgaccc gtactcttta gtcactgacg tcagattatt tttataacgt   2400

tccctgacag ttcagagtcc cttcgaattg cacttttctg gtttcgctta tttaattaaa   2460

agagatgagt gtaagtataa aaaatgaagg tgaaataacc attggaattg tatttggtta   2520

cttaatactg ttccacaaca tcttgggacg tctgttttcc tttggagagt gaggccttgt   2580

tattattctt ttctgataaa gaaaacattt tatttccttt gggcttgcat tagctctttc   2640

ctagcaaccc attatcccag ctcagtacct ttcaaacaga aaactagagt ctggggtttt   2700

gttgtgatct gaatttgtaa gttattaatg tgaaaggggg agcaggaagc tccccctttg   2760

cacaaagggg gatttgtttg cacaaagttc actgtaaata ctgtgagaat tgaattctga   2820

aaaggtcata tttagtgatt tcaaaagcac acatttaaat gaagactgac taaataaaag   2880

gtaccacaca ctt                                                      2893


<210>  8317
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  8317

Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
1               5                   10                  15


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
            20                  25                  30


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
        35                  40                  45


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
    50                  55                  60


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
65                  70                  75                  80


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
                85                  90                  95


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
            100                 105                 110


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
        115                 120                 125


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
    130                 135                 140


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
145                 150                 155                 160


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
                165                 170                 175


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
            180                 185                 190


Pro 



<210>  8318
<211>  3679
<212>  DNA
<213>  Homo sapiens

<400>  8318
gtgacgttac aggactgagg agggaggaag taaaagggag ctgtgactgt ggtacgtatc     60

tgaaagcaag tgttagagag ggagtggaga acgcataagc aagctggttt gaccagaaac    120

agaactgcct gtgacagatt aagagacaag caaggcttgg aatctgagag caagcaaaga    180

gagtggaaat ttacagctgc cctatgtgag tgttcaagtg atcattttct ggtaacgttt    240

tccagtggta actgttactc ttcaaaaaga gggacagaaa gtcaagacct aattgtggaa    300

actcttttct ctgccacgct tggtaatagg aggcaacctc tattaaatgg acgataaagg    360

ctacttcatc taaagtgctt tgagctcaag aaagagctgt cttcagcacc tcaccatgtg    420

tctacatttt gttgcttaga aaagcctagg catttctgta acatttgcat tccatattgg    480

aagaagagat ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca    540

gcagaaattg tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag    600

acagacaagg cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt    660

ggtacaaacg agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac    720

agcagtggcc tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa    780

aaagatgtga cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct    840

actgtggagt atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa    900

gccccacaga ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca    960

cttgccaaaa tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg   1020

tcaacatttg atattgcttc agatgccttt gctactttca aggatttact aaccagacat   1080

aaagtgttgg tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag   1140

aaattgcttc agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag   1200

ctgatcctgg accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac   1260

ctgaaactca tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt   1320

catgttttta aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg   1380

ttaaaaaatc agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat   1440

gatgagcagt tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa   1500

acggcccctt gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt   1560

gtacagtgtg tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt   1620

ttctgctgta attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc   1680

tagaataata tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg   1740

tatcagatgt tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc   1800

cgctaaatgg gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca   1860

ggggagaact gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac   1920

acagatcgct cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt   1980

gtgtcctttg ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga   2040

tccagtgctc cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct   2100

cctcagcatg gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc   2160

aactgagcag gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg   2220

tgacctgctt gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat   2280

attagcttcc agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa   2340

tgctttctgc tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc   2400

acaaaccatg ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg   2460

aaggagaaat gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag   2520

ccattgtatc agatgttgat aaaagcaatt tttttctaat aagctgtcat tctataattg   2580

cccatcacag tctttagtga acacatagaa agcctataca gttttggtcc tgaatagtct   2640

cttgtgacta ggatgattga ggtgttaatt cctcttcctt ataaaaaggc ttggaatcaa   2700

aaatatttta aaaggccgtg gtttcgtttc agacatcaac catctaaaac gggattttaa   2760

agcgatattt tacaagaatg aaaggcacaa ttgttgatct gtatttttta cacttcagtt   2820

tctaaatcat gaatcgttgc cttccacagg aaccctccct tatacattac ttgagtgttg   2880

tgtagttttt cttcagccag gtatttctct gcctagagag gggaagagaa atgtgttctc   2940

caggactgat cccctttgta gattttgtac ctgaagagtt acctggcagg gcaccaccct   3000

tggctaggcc caggtgtgtg tttctttctt gcctggcatg gaccccgagg caggtgatgt   3060

ggggcctggc gcacctcccc gctttggcag ctgtggcctc cctggccagt gcccttgcag   3120

gaggccggcc ggcagcctga tgacccgtac tctttagtca ctgacgtcag attattttta   3180

taacgttccc tgacagttca gagtcccttc gaattgcact tttctggttt cgcttattta   3240

attaaaagag atgagtgtaa gtataaaaaa tgaaggtgaa ataaccattg gaattgtatt   3300

tggttactta atactgttcc acaacatctt gggacgtctg ttttcctttg gagagtgagg   3360

ccttgttatt attcttttct gataaagaaa acattttatt tcctttgggc ttgcattagc   3420

tctttcctag caacccatta tcccagctca gtacctttca aacagaaaac tagagtctgg   3480

ggttttgttg tgatctgaat ttgtaagtta ttaatgtgaa agggggagca ggaagctccc   3540

cctttgcaca aagggggatt tgtttgcaca aagttcactg taaatactgt gagaattgaa   3600

ttctgaaaag gtcatattta gtgatttcaa aagcacacat ttaaatgaag actgactaaa   3660

taaaaggtac cacacactt                                                3679


<210>  8319
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8319

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8320
<211>  3673
<212>  DNA
<213>  Homo sapiens

<400>  8320
gagaacctag tatcacacta ggcttctgaa aacaccaatc aagagttgct taatgcaggg     60

gtcccttacc cctgggctgc agacctgtac ctgtccatgg cctgttagga accgggcagc    120

acagtaggag gactgaggag ggaggaagta aaagggagct gtgactgtgg tacgtatctg    180

aaagcaagtg ttagagaggg agtggagaac gcataagcaa gctggtttga ccagaaacag    240

aactgcctgt gacagattaa gagacaagca aggcttggaa tctgagagca agcaaagaga    300

gtggaaattt acagctgccc tatgaggcaa cctctattaa atggacgata aaggctactt    360

catctaaagt gctttgagct caagaaagag ctgtcttcag cacctcacca tgtgtctaca    420

ttttgttgct tagaaaagcc taggcatttc tgtaacattt gcattccata ttggaagaag    480

agatttctac acatgaaaaa aatgcctttg tttagtaaat cacacaaaaa tccagcagaa    540

attgtgaaaa tcctgaaaga caatttggcc attttggaaa agcaagacaa aaagacagac    600

aaggcttcag aagaagtgtc taaatcactg caagcaatga aagaaattct gtgtggtaca    660

aacgagaaag aacccccaac agaagcagtg gctcagctag cacaagaact ctacagcagt    720

ggcctgctag tgacactgat agctgacctg cagctgatag actttgaggg aaaaaaagat    780

gtgacccaga tatttaacaa catcttgaga agacagatag gcactcggag tcctactgtg    840

gagtatatta gtgctcatcc tcatatcctg tttatgctcc tcaaaggata tgaagcccca    900

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    960

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca   1020

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg   1080

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg   1140

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc   1200

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa   1260

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt   1320

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa   1380

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag   1440

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc   1500

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag   1560

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc   1620

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat   1680

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag   1740

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1800

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1860

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1920

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1980

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   2040

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   2100

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   2160

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   2220

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   2280

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   2340

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   2400

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   2460

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   2520

tatcagatgt tgataaaagc aatttttttc taataagctg tcattctata attgcccatc   2580

acagtcttta gtgaacacat agaaagccta tacagttttg gtcctgaata gtctcttgtg   2640

actaggatga ttgaggtgtt aattcctctt ccttataaaa aggcttggaa tcaaaaatat   2700

tttaaaaggc cgtggtttcg tttcagacat caaccatcta aaacgggatt ttaaagcgat   2760

attttacaag aatgaaaggc acaattgttg atctgtattt tttacacttc agtttctaaa   2820

tcatgaatcg ttgccttcca caggaaccct cccttataca ttacttgagt gttgtgtagt   2880

ttttcttcag ccaggtattt ctctgcctag agaggggaag agaaatgtgt tctccaggac   2940

tgatcccctt tgtagatttt gtacctgaag agttacctgg cagggcacca cccttggcta   3000

ggcccaggtg tgtgtttctt tcttgcctgg catggacccc gaggcaggtg atgtggggcc   3060

tggcgcacct ccccgctttg gcagctgtgg cctccctggc cagtgccctt gcaggaggcc   3120

ggccggcagc ctgatgaccc gtactcttta gtcactgacg tcagattatt tttataacgt   3180

tccctgacag ttcagagtcc cttcgaattg cacttttctg gtttcgctta tttaattaaa   3240

agagatgagt gtaagtataa aaaatgaagg tgaaataacc attggaattg tatttggtta   3300

cttaatactg ttccacaaca tcttgggacg tctgttttcc tttggagagt gaggccttgt   3360

tattattctt ttctgataaa gaaaacattt tatttccttt gggcttgcat tagctctttc   3420

ctagcaaccc attatcccag ctcagtacct ttcaaacaga aaactagagt ctggggtttt   3480

gttgtgatct gaatttgtaa gttattaatg tgaaaggggg agcaggaagc tccccctttg   3540

cacaaagggg gatttgtttg cacaaagttc actgtaaata ctgtgagaat tgaattctga   3600

aaaggtcata tttagtgatt tcaaaagcac acatttaaat gaagactgac taaataaaag   3660

gtaccacaca ctt                                                      3673


<210>  8321
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8321

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8322
<211>  3429
<212>  DNA
<213>  Homo sapiens

<400>  8322
agcgttttgt tagggaagaa gtggagaaca gatattggaa ggcaattagc tgtctctaat     60

acattgataa aatatataac tataactgca aaatgctaat aacccagcag aggagtagat    120

ttgggaacat aagatgaaaa agtcaacaag tgcattgatc acaacatatg gtaatgatag    180

cgtgattgtg atgacctttg ttttatacct ccttttacat tccatattgg aagaagagat    240

ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca gcagaaattg    300

tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag acagacaagg    360

cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt ggtacaaacg    420

agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac agcagtggcc    480

tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa aaagatgtga    540

cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct actgtggagt    600

atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa gccccacaga    660

ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca cttgccaaaa    720

tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg tcaacatttg    780

atattgcttc agatgccttt gctactttca aggatttact aaccagacat aaagtgttgg    840

tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag aaattgcttc    900

agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag ctgatcctgg    960

accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac ctgaaactca   1020

tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt catgttttta   1080

aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg ttaaaaaatc   1140

agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat gatgagcagt   1200

tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa acggcccctt   1260

gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt gtacagtgtg   1320

tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt ttctgctgta   1380

attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc tagaataata   1440

tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg tatcagatgt   1500

tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc cgctaaatgg   1560

gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca ggggagaact   1620

gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac acagatcgct   1680

cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt gtgtcctttg   1740

ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga tccagtgctc   1800

cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct cctcagcatg   1860

gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc aactgagcag   1920

gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg tgacctgctt   1980

gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat attagcttcc   2040

agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa tgctttctgc   2100

tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc acaaaccatg   2160

ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg aaggagaaat   2220

gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag ccattgtatc   2280

agatgttgat aaaagcaatt tttttctaat aagctgtcat tctataattg cccatcacag   2340

tctttagtga acacatagaa agcctataca gttttggtcc tgaatagtct cttgtgacta   2400

ggatgattga ggtgttaatt cctcttcctt ataaaaaggc ttggaatcaa aaatatttta   2460

aaaggccgtg gtttcgtttc agacatcaac catctaaaac gggattttaa agcgatattt   2520

tacaagaatg aaaggcacaa ttgttgatct gtatttttta cacttcagtt tctaaatcat   2580

gaatcgttgc cttccacagg aaccctccct tatacattac ttgagtgttg tgtagttttt   2640

cttcagccag gtatttctct gcctagagag gggaagagaa atgtgttctc caggactgat   2700

cccctttgta gattttgtac ctgaagagtt acctggcagg gcaccaccct tggctaggcc   2760

caggtgtgtg tttctttctt gcctggcatg gaccccgagg caggtgatgt ggggcctggc   2820

gcacctcccc gctttggcag ctgtggcctc cctggccagt gcccttgcag gaggccggcc   2880

ggcagcctga tgacccgtac tctttagtca ctgacgtcag attattttta taacgttccc   2940

tgacagttca gagtcccttc gaattgcact tttctggttt cgcttattta attaaaagag   3000

atgagtgtaa gtataaaaaa tgaaggtgaa ataaccattg gaattgtatt tggttactta   3060

atactgttcc acaacatctt gggacgtctg ttttcctttg gagagtgagg ccttgttatt   3120

attcttttct gataaagaaa acattttatt tcctttgggc ttgcattagc tctttcctag   3180

caacccatta tcccagctca gtacctttca aacagaaaac tagagtctgg ggttttgttg   3240

tgatctgaat ttgtaagtta ttaatgtgaa agggggagca ggaagctccc cctttgcaca   3300

aagggggatt tgtttgcaca aagttcactg taaatactgt gagaattgaa ttctgaaaag   3360

gtcatattta gtgatttcaa aagcacacat ttaaatgaag actgactaaa taaaaggtac   3420

cacacactt                                                           3429


<210>  8323
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8323

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8324
<211>  3787
<212>  DNA
<213>  Homo sapiens

<400>  8324
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaagcattc catattggaa gaagagattt    600

ctacacatga aaaaaatgcc tttgtttagt aaatcacaca aaaatccagc agaaattgtg    660

aaaatcctga aagacaattt ggccattttg gaaaagcaag acaaaaagac agacaaggct    720

tcagaagaag tgtctaaatc actgcaagca atgaaagaaa ttctgtgtgg tacaaacgag    780

aaagaacccc caacagaagc agtggctcag ctagcacaag aactctacag cagtggcctg    840

ctagtgacac tgatagctga cctgcagctg atagactttg agggaaaaaa agatgtgacc    900

cagatattta acaacatctt gagaagacag ataggcactc ggagtcctac tgtggagtat    960

attagtgctc atcctcatat cctgtttatg ctcctcaaag gatatgaagc cccacagatt   1020

gccttacgtt gtgggattat gctgagagaa tgtattcgac atgaaccact tgccaaaatc   1080

atcctctttt ctaatcaatt cagagatttc tttaagtacg tggagttgtc aacatttgat   1140

attgcttcag atgcctttgc tactttcaag gatttactaa ccagacataa agtgttggta   1200

gcagacttct tagaacaaaa ttacgacact atttttgaag actatgagaa attgcttcag   1260

tctgagaatt atgttactaa gagacagtct ttaaagctgc taggggagct gatcctggac   1320

cgtcacaact ttgccatcat gacaaagtat atcagcaagc cggagaacct gaaactcatg   1380

atgaacctcc ttcgggataa aagtcccaac atccagtttg aagcctttca tgtttttaag   1440

gtgtttgtgg ccagtcctca caaaacacag cctattgtgg agatcctgtt aaaaaatcag   1500

cccaaactca ttgagtttct gagcagcttc caaaaagaaa ggacggatga tgagcagttc   1560

gctgacgaga agaactactt gattaaacag atccgagact tgaagaaaac ggccccttga   1620

agagctcccc ggcccctgtc acagtcagtc gtctcatttg tccagtttgt acagtgtgtc   1680

atttcagaaa gtcatcattc ttgggaagac tttggaggtg cctatttttt ctgctgtaat   1740

tgttctgggt agatggagta taaacatttg aatggaaaaa aattaaccta gaataatata   1800

ttcattttag tcaagtctgt gattatttat gtgaaatgag aaccattgta tcagatgttg   1860

ataaaagcaa ttttaacttg cagatgtgag cccctgggca caatgagccg ctaaatggga   1920

gctcaattga caggcatcac caagtcttca aggaggactg agttctcagg ggagaactgg   1980

gaatggggcc agggtgcaaa aatgctttgc ccatctgtag gtagacacac agatcgctca   2040

gggcactgag agatcccaga aggtaacgtt aatgttttca gtcattgtgt gtcctttgtt   2100

gctgccaatg tctttggact gtaatcagtg catccacacc tcccaggatc cagtgctccc   2160

tctcagctca gtctcccctc tctccctgtc ctgcattcca tcccagctcc tcagcatggc   2220

ctcagtgggc gcacccatgc ctcccgcagt ccaggtgagc aggggagcaa ctgagcagga   2280

agaggatgga tcaacaaggg tcacggggaa taggggaccc acggggtgtg acctgcttgc   2340

tagagaactg tgaacatgtg gctctggata gagtgactgc tgctccatat tagcttccag   2400

agggtgagtg agggacagaa tatttccttc ataatggtca tgggtgaatg ctttctgctg   2460

taagtgtctt ttagagtagg aatcagcata gtgggatgcc cagcaggcac aaaccatggg   2520

tccagggagt ctcagcgggg aacttctatc agtatcaata accattggaa ggagaaatga   2580

ttcatgtgtg aaaaaattct cagatccatc aataaatttt tttcagagcc attgtatcag   2640

atgttgataa aagcaatttt tttctaataa gctgtcattc tataattgcc catcacagtc   2700

tttagtgaac acatagaaag cctatacagt tttggtcctg aatagtctct tgtgactagg   2760

atgattgagg tgttaattcc tcttccttat aaaaaggctt ggaatcaaaa atattttaaa   2820

aggccgtggt ttcgtttcag acatcaacca tctaaaacgg gattttaaag cgatatttta   2880

caagaatgaa aggcacaatt gttgatctgt attttttaca cttcagtttc taaatcatga   2940

atcgttgcct tccacaggaa ccctccctta tacattactt gagtgttgtg tagtttttct   3000

tcagccaggt atttctctgc ctagagaggg gaagagaaat gtgttctcca ggactgatcc   3060

cctttgtaga ttttgtacct gaagagttac ctggcagggc accacccttg gctaggccca   3120

ggtgtgtgtt tctttcttgc ctggcatgga ccccgaggca ggtgatgtgg ggcctggcgc   3180

acctccccgc tttggcagct gtggcctccc tggccagtgc ccttgcagga ggccggccgg   3240

cagcctgatg acccgtactc tttagtcact gacgtcagat tatttttata acgttccctg   3300

acagttcaga gtcccttcga attgcacttt tctggtttcg cttatttaat taaaagagat   3360

gagtgtaagt ataaaaaatg aaggtgaaat aaccattgga attgtatttg gttacttaat   3420

actgttccac aacatcttgg gacgtctgtt ttcctttgga gagtgaggcc ttgttattat   3480

tcttttctga taaagaaaac attttatttc ctttgggctt gcattagctc tttcctagca   3540

acccattatc ccagctcagt acctttcaaa cagaaaacta gagtctgggg ttttgttgtg   3600

atctgaattt gtaagttatt aatgtgaaag ggggagcagg aagctccccc tttgcacaaa   3660

gggggatttg tttgcacaaa gttcactgta aatactgtga gaattgaatt ctgaaaaggt   3720

catatttagt gatttcaaaa gcacacattt aaatgaagac tgactaaata aaaggtacca   3780

cacactt                                                             3787


<210>  8325
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8325

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8326
<211>  4176
<212>  DNA
<213>  Homo sapiens

<400>  8326
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaaggcaaa tctttcatct gcagttttga    600

ctctatccca atggagaaat tgttaatctt ttagtaagca ttaagaattg tatagaaaat    660

gcagaatttg tttggaagaa aagcatggat aattcatttg tgatgaatgt tgactccaca    720

aagggtttgt tcaagtattt ggagacggtt gttaaattgc cttttaagga ggactgagga    780

gggaggaagt aaaagggagc tgtgactgtg gtacgtatct gaaagcaagt gttagagagg    840

gagtggagaa cgcataagca agctggtttg accagaaaca gaactgcctg tgacagatta    900

agagacaagc aaggcttgga atctgagagc aagcaaagag agtggaaatt tacagctgcc    960

ctatcattcc atattggaag aagagatttc tacacatgaa aaaaatgcct ttgtttagta   1020

aatcacacaa aaatccagca gaaattgtga aaatcctgaa agacaatttg gccattttgg   1080

aaaagcaaga caaaaagaca gacaaggctt cagaagaagt gtctaaatca ctgcaagcaa   1140

tgaaagaaat tctgtgtggt acaaacgaga aagaaccccc aacagaagca gtggctcagc   1200

tagcacaaga actctacagc agtggcctgc tagtgacact gatagctgac ctgcagctga   1260

tagactttga gggaaaaaaa gatgtgaccc agatatttaa caacatcttg agaagacaga   1320

taggcactcg gagtcctact gtggagtata ttagtgctca tcctcatatc ctgtttatgc   1380

tcctcaaagg atatgaagcc ccacagattg ccttacgttg tgggattatg ctgagagaat   1440

gtattcgaca tgaaccactt gccaaaatca tcctcttttc taatcaattc agagatttct   1500

ttaagtacgt ggagttgtca acatttgata ttgcttcaga tgcctttgct actttcaagg   1560

atttactaac cagacataaa gtgttggtag cagacttctt agaacaaaat tacgacacta   1620

tttttgaaga ctatgagaaa ttgcttcagt ctgagaatta tgttactaag agacagtctt   1680

taaagctgct aggggagctg atcctggacc gtcacaactt tgccatcatg acaaagtata   1740

tcagcaagcc ggagaacctg aaactcatga tgaacctcct tcgggataaa agtcccaaca   1800

tccagtttga agcctttcat gtttttaagg tgtttgtggc cagtcctcac aaaacacagc   1860

ctattgtgga gatcctgtta aaaaatcagc ccaaactcat tgagtttctg agcagcttcc   1920

aaaaagaaag gacggatgat gagcagttcg ctgacgagaa gaactacttg attaaacaga   1980

tccgagactt gaagaaaacg gccccttgaa gagctccccg gcccctgtca cagtcagtcg   2040

tctcatttgt ccagtttgta cagtgtgtca tttcagaaag tcatcattct tgggaagact   2100

ttggaggtgc ctattttttc tgctgtaatt gttctgggta gatggagtat aaacatttga   2160

atggaaaaaa attaacctag aataatatat tcattttagt caagtctgtg attatttatg   2220

tgaaatgaga accattgtat cagatgttga taaaagcaat tttaacttgc agatgtgagc   2280

ccctgggcac aatgagccgc taaatgggag ctcaattgac aggcatcacc aagtcttcaa   2340

ggaggactga gttctcaggg gagaactggg aatggggcca gggtgcaaaa atgctttgcc   2400

catctgtagg tagacacaca gatcgctcag ggcactgaga gatcccagaa ggtaacgtta   2460

atgttttcag tcattgtgtg tcctttgttg ctgccaatgt ctttggactg taatcagtgc   2520

atccacacct cccaggatcc agtgctccct ctcagctcag tctcccctct ctccctgtcc   2580

tgcattccat cccagctcct cagcatggcc tcagtgggcg cacccatgcc tcccgcagtc   2640

caggtgagca ggggagcaac tgagcaggaa gaggatggat caacaagggt cacggggaat   2700

aggggaccca cggggtgtga cctgcttgct agagaactgt gaacatgtgg ctctggatag   2760

agtgactgct gctccatatt agcttccaga gggtgagtga gggacagaat atttccttca   2820

taatggtcat gggtgaatgc tttctgctgt aagtgtcttt tagagtagga atcagcatag   2880

tgggatgccc agcaggcaca aaccatgggt ccagggagtc tcagcgggga acttctatca   2940

gtatcaataa ccattggaag gagaaatgat tcatgtgtga aaaaattctc agatccatca   3000

ataaattttt ttcagagcca ttgtatcaga tgttgataaa agcaattttt ttctaataag   3060

ctgtcattct ataattgccc atcacagtct ttagtgaaca catagaaagc ctatacagtt   3120

ttggtcctga atagtctctt gtgactagga tgattgaggt gttaattcct cttccttata   3180

aaaaggcttg gaatcaaaaa tattttaaaa ggccgtggtt tcgtttcaga catcaaccat   3240

ctaaaacggg attttaaagc gatattttac aagaatgaaa ggcacaattg ttgatctgta   3300

ttttttacac ttcagtttct aaatcatgaa tcgttgcctt ccacaggaac cctcccttat   3360

acattacttg agtgttgtgt agtttttctt cagccaggta tttctctgcc tagagagggg   3420

aagagaaatg tgttctccag gactgatccc ctttgtagat tttgtacctg aagagttacc   3480

tggcagggca ccacccttgg ctaggcccag gtgtgtgttt ctttcttgcc tggcatggac   3540

cccgaggcag gtgatgtggg gcctggcgca cctccccgct ttggcagctg tggcctccct   3600

ggccagtgcc cttgcaggag gccggccggc agcctgatga cccgtactct ttagtcactg   3660

acgtcagatt atttttataa cgttccctga cagttcagag tcccttcgaa ttgcactttt   3720

ctggtttcgc ttatttaatt aaaagagatg agtgtaagta taaaaaatga aggtgaaata   3780

accattggaa ttgtatttgg ttacttaata ctgttccaca acatcttggg acgtctgttt   3840

tcctttggag agtgaggcct tgttattatt cttttctgat aaagaaaaca ttttatttcc   3900

tttgggcttg cattagctct ttcctagcaa cccattatcc cagctcagta cctttcaaac   3960

agaaaactag agtctggggt tttgttgtga tctgaatttg taagttatta atgtgaaagg   4020

gggagcagga agctccccct ttgcacaaag ggggatttgt ttgcacaaag ttcactgtaa   4080

atactgtgag aattgaattc tgaaaaggtc atatttagtg atttcaaaag cacacattta   4140

aatgaagact gactaaataa aaggtaccac acactt                             4176


<210>  8327
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8327

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8328
<211>  1741
<212>  DNA
<213>  Homo sapiens

<400>  8328
gagtatatct aagtgtttca gaatacactc aaattccaga atacgtctgc aatagtgcca     60

ggcacatagt agatcttcag tggatattga atgaatcgtg acaaatgata tgaagcccca    120

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    180

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca    240

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg    300

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg    360

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc    420

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa    480

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt    540

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa    600

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag    660

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc    720

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag    780

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc    840

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat    900

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag    960

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1020

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1080

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1140

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1200

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   1260

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   1320

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   1380

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   1440

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   1500

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   1560

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   1620

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   1680

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   1740

t                                                                   1741


<210>  8329
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  8329

Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
1               5                   10                  15


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
            20                  25                  30


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
        35                  40                  45


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
    50                  55                  60


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
65                  70                  75                  80


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
                85                  90                  95


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
            100                 105                 110


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
        115                 120                 125


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
    130                 135                 140


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
145                 150                 155                 160


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
                165                 170                 175


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
            180                 185                 190


Pro 



<210>  8330
<211>  2527
<212>  DNA
<213>  Homo sapiens

<400>  8330
gtgacgttac aggactgagg agggaggaag taaaagggag ctgtgactgt ggtacgtatc     60

tgaaagcaag tgttagagag ggagtggaga acgcataagc aagctggttt gaccagaaac    120

agaactgcct gtgacagatt aagagacaag caaggcttgg aatctgagag caagcaaaga    180

gagtggaaat ttacagctgc cctatgtgag tgttcaagtg atcattttct ggtaacgttt    240

tccagtggta actgttactc ttcaaaaaga gggacagaaa gtcaagacct aattgtggaa    300

actcttttct ctgccacgct tggtaatagg aggcaacctc tattaaatgg acgataaagg    360

ctacttcatc taaagtgctt tgagctcaag aaagagctgt cttcagcacc tcaccatgtg    420

tctacatttt gttgcttaga aaagcctagg catttctgta acatttgcat tccatattgg    480

aagaagagat ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca    540

gcagaaattg tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag    600

acagacaagg cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt    660

ggtacaaacg agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac    720

agcagtggcc tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa    780

aaagatgtga cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct    840

actgtggagt atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa    900

gccccacaga ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca    960

cttgccaaaa tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg   1020

tcaacatttg atattgcttc agatgccttt gctactttca aggatttact aaccagacat   1080

aaagtgttgg tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag   1140

aaattgcttc agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag   1200

ctgatcctgg accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac   1260

ctgaaactca tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt   1320

catgttttta aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg   1380

ttaaaaaatc agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat   1440

gatgagcagt tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa   1500

acggcccctt gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt   1560

gtacagtgtg tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt   1620

ttctgctgta attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc   1680

tagaataata tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg   1740

tatcagatgt tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc   1800

cgctaaatgg gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca   1860

ggggagaact gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac   1920

acagatcgct cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt   1980

gtgtcctttg ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga   2040

tccagtgctc cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct   2100

cctcagcatg gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc   2160

aactgagcag gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg   2220

tgacctgctt gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat   2280

attagcttcc agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa   2340

tgctttctgc tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc   2400

acaaaccatg ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg   2460

aaggagaaat gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag   2520

ccattgt                                                             2527


<210>  8331
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8331

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8332
<211>  2521
<212>  DNA
<213>  Homo sapiens

<400>  8332
gagaacctag tatcacacta ggcttctgaa aacaccaatc aagagttgct taatgcaggg     60

gtcccttacc cctgggctgc agacctgtac ctgtccatgg cctgttagga accgggcagc    120

acagtaggag gactgaggag ggaggaagta aaagggagct gtgactgtgg tacgtatctg    180

aaagcaagtg ttagagaggg agtggagaac gcataagcaa gctggtttga ccagaaacag    240

aactgcctgt gacagattaa gagacaagca aggcttggaa tctgagagca agcaaagaga    300

gtggaaattt acagctgccc tatgaggcaa cctctattaa atggacgata aaggctactt    360

catctaaagt gctttgagct caagaaagag ctgtcttcag cacctcacca tgtgtctaca    420

ttttgttgct tagaaaagcc taggcatttc tgtaacattt gcattccata ttggaagaag    480

agatttctac acatgaaaaa aatgcctttg tttagtaaat cacacaaaaa tccagcagaa    540

attgtgaaaa tcctgaaaga caatttggcc attttggaaa agcaagacaa aaagacagac    600

aaggcttcag aagaagtgtc taaatcactg caagcaatga aagaaattct gtgtggtaca    660

aacgagaaag aacccccaac agaagcagtg gctcagctag cacaagaact ctacagcagt    720

ggcctgctag tgacactgat agctgacctg cagctgatag actttgaggg aaaaaaagat    780

gtgacccaga tatttaacaa catcttgaga agacagatag gcactcggag tcctactgtg    840

gagtatatta gtgctcatcc tcatatcctg tttatgctcc tcaaaggata tgaagcccca    900

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    960

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca   1020

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg   1080

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg   1140

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc   1200

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa   1260

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt   1320

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa   1380

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag   1440

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc   1500

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag   1560

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc   1620

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat   1680

aatatattca ttttagtcaa gtctgtgatt atttatgtga aatgagaacc attgtatcag   1740

atgttgataa aagcaatttt aacttgcaga tgtgagcccc tgggcacaat gagccgctaa   1800

atgggagctc aattgacagg catcaccaag tcttcaagga ggactgagtt ctcaggggag   1860

aactgggaat ggggccaggg tgcaaaaatg ctttgcccat ctgtaggtag acacacagat   1920

cgctcagggc actgagagat cccagaaggt aacgttaatg ttttcagtca ttgtgtgtcc   1980

tttgttgctg ccaatgtctt tggactgtaa tcagtgcatc cacacctccc aggatccagt   2040

gctccctctc agctcagtct cccctctctc cctgtcctgc attccatccc agctcctcag   2100

catggcctca gtgggcgcac ccatgcctcc cgcagtccag gtgagcaggg gagcaactga   2160

gcaggaagag gatggatcaa caagggtcac ggggaatagg ggacccacgg ggtgtgacct   2220

gcttgctaga gaactgtgaa catgtggctc tggatagagt gactgctgct ccatattagc   2280

ttccagaggg tgagtgaggg acagaatatt tccttcataa tggtcatggg tgaatgcttt   2340

ctgctgtaag tgtcttttag agtaggaatc agcatagtgg gatgcccagc aggcacaaac   2400

catgggtcca gggagtctca gcggggaact tctatcagta tcaataacca ttggaaggag   2460

aaatgattca tgtgtgaaaa aattctcaga tccatcaata aatttttttc agagccattg   2520

t                                                                   2521


<210>  8333
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8333

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8334
<211>  2277
<212>  DNA
<213>  Homo sapiens

<400>  8334
agcgttttgt tagggaagaa gtggagaaca gatattggaa ggcaattagc tgtctctaat     60

acattgataa aatatataac tataactgca aaatgctaat aacccagcag aggagtagat    120

ttgggaacat aagatgaaaa agtcaacaag tgcattgatc acaacatatg gtaatgatag    180

cgtgattgtg atgacctttg ttttatacct ccttttacat tccatattgg aagaagagat    240

ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca gcagaaattg    300

tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag acagacaagg    360

cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt ggtacaaacg    420

agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac agcagtggcc    480

tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa aaagatgtga    540

cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct actgtggagt    600

atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa gccccacaga    660

ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca cttgccaaaa    720

tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg tcaacatttg    780

atattgcttc agatgccttt gctactttca aggatttact aaccagacat aaagtgttgg    840

tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag aaattgcttc    900

agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag ctgatcctgg    960

accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac ctgaaactca   1020

tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt catgttttta   1080

aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg ttaaaaaatc   1140

agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat gatgagcagt   1200

tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa acggcccctt   1260

gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt gtacagtgtg   1320

tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt ttctgctgta   1380

attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc tagaataata   1440

tattcatttt agtcaagtct gtgattattt atgtgaaatg agaaccattg tatcagatgt   1500

tgataaaagc aattttaact tgcagatgtg agcccctggg cacaatgagc cgctaaatgg   1560

gagctcaatt gacaggcatc accaagtctt caaggaggac tgagttctca ggggagaact   1620

gggaatgggg ccagggtgca aaaatgcttt gcccatctgt aggtagacac acagatcgct   1680

cagggcactg agagatccca gaaggtaacg ttaatgtttt cagtcattgt gtgtcctttg   1740

ttgctgccaa tgtctttgga ctgtaatcag tgcatccaca cctcccagga tccagtgctc   1800

cctctcagct cagtctcccc tctctccctg tcctgcattc catcccagct cctcagcatg   1860

gcctcagtgg gcgcacccat gcctcccgca gtccaggtga gcaggggagc aactgagcag   1920

gaagaggatg gatcaacaag ggtcacgggg aataggggac ccacggggtg tgacctgctt   1980

gctagagaac tgtgaacatg tggctctgga tagagtgact gctgctccat attagcttcc   2040

agagggtgag tgagggacag aatatttcct tcataatggt catgggtgaa tgctttctgc   2100

tgtaagtgtc ttttagagta ggaatcagca tagtgggatg cccagcaggc acaaaccatg   2160

ggtccaggga gtctcagcgg ggaacttcta tcagtatcaa taaccattgg aaggagaaat   2220

gattcatgtg tgaaaaaatt ctcagatcca tcaataaatt tttttcagag ccattgt      2277


<210>  8335
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8335

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8336
<211>  2300
<212>  DNA
<213>  Homo sapiens

<400>  8336
agcgctctcg gcttgtctcg cgcactgtag ctgagccaat ggagttactc gtagtcgaga     60

ggccggcatc actggagtgg tggcgcagct gtttcctccg gatatccatc aaatattgag    120

aagaaagaat atcaggagca aagtgttcta agttgctgtt cagaacgtaa agatgcgaac    180

cccaaatcag tggtttgttc attcttcatg caagagcaat gcactaaagg agagaagcag    240

cattccatat tggaagaaga gatttctaca catgaaaaaa atgcctttgt ttagtaaatc    300

acacaaaaat ccagcagaaa ttgtgaaaat cctgaaagac aatttggcca ttttggaaaa    360

gcaagacaaa aagacagaca aggcttcaga agaagtgtct aaatcactgc aagcaatgaa    420

agaaattctg tgtggtacaa acgagaaaga acccccaaca gaagcagtgg ctcagctagc    480

acaagaactc tacagcagtg gcctgctagt gacactgata gctgacctgc agctgataga    540

ctttgaggga aaaaaagatg tgacccagat atttaacaac atcttgagaa gacagatagg    600

cactcggagt cctactgtgg agtatattag tgctcatcct catatcctgt ttatgctcct    660

caaaggatat gaagccccac agattgcctt acgttgtggg attatgctga gagaatgtat    720

tcgacatgaa ccacttgcca aaatcatcct cttttctaat caattcagag atttctttaa    780

gtacgtggag ttgtcaacat ttgatattgc ttcagatgcc tttgctactt tcaaggattt    840

actaaccaga cataaagtgt tggtagcaga cttcttagaa caaaattacg acactatttt    900

tgaagactat gagaaattgc ttcagtctga gaattatgtt actaagagac agtctttaaa    960

gctgctaggg gagctgatcc tggaccgtca caactttgcc atcatgacaa agtatatcag   1020

caagccggag aacctgaaac tcatgatgaa cctccttcgg gataaaagtc ccaacatcca   1080

gtttgaagcc tttcatgttt ttaaggtgtt tgtggccagt cctcacaaaa cacagcctat   1140

tgtggagatc ctgttaaaaa atcagcccaa actcattgag tttctgagca gcttccaaaa   1200

agaaaggacg gatgatgagc agttcgctga cgagaagaac tacttgatta aacagatccg   1260

agacttgaag aaaacggccc cttgaagagc tccccggccc ctgtcacagt cagtcgtctc   1320

atttgtccag tttgtacagt gtgtcatttc agaaagtcat cattcttggg aagactttgg   1380

aggtgcctat tttttctgct gtaattgttc tgggtagatg gagtataaac atttgaatgg   1440

aaaaaaatta acctagaata atatattcat tttagtcaag tctgtgatta tttatgtgaa   1500

atgagaacca ttgtatcaga tgttgataaa agcaatttta acttgcagat gtgagcccct   1560

gggcacaatg agccgctaaa tgggagctca attgacaggc atcaccaagt cttcaaggag   1620

gactgagttc tcaggggaga actgggaatg gggccagggt gcaaaaatgc tttgcccatc   1680

tgtaggtaga cacacagatc gctcagggca ctgagagatc ccagaaggta acgttaatgt   1740

tttcagtcat tgtgtgtcct ttgttgctgc caatgtcttt ggactgtaat cagtgcatcc   1800

acacctccca ggatccagtg ctccctctca gctcagtctc ccctctctcc ctgtcctgca   1860

ttccatccca gctcctcagc atggcctcag tgggcgcacc catgcctccc gcagtccagg   1920

tgagcagggg agcaactgag caggaagagg atggatcaac aagggtcacg gggaataggg   1980

gacccacggg gtgtgacctg cttgctagag aactgtgaac atgtggctct ggatagagtg   2040

actgctgctc catattagct tccagagggt gagtgaggga cagaatattt ccttcataat   2100

ggtcatgggt gaatgctttc tgctgtaagt gtcttttaga gtaggaatca gcatagtggg   2160

atgcccagca ggcacaaacc atgggtccag ggagtctcag cggggaactt ctatcagtat   2220

caataaccat tggaaggaga aatgattcat gtgtgaaaaa attctcagat ccatcaataa   2280

atttttttca gagccattgt                                               2300


<210>  8337
<211>  370
<212>  PRT
<213>  Homo sapiens

<400>  8337

Met Arg Thr Pro Asn Gln Trp Phe Val His Ser Ser Cys Lys Ser Asn 
1               5                   10                  15


Ala Leu Lys Glu Arg Ser Ser Ile Pro Tyr Trp Lys Lys Arg Phe Leu 
            20                  25                  30


His Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala 
        35                  40                  45


Glu Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln 
    50                  55                  60


Asp Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln 
65                  70                  75                  80


Ala Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr 
                85                  90                  95


Glu Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu 
            100                 105                 110


Val Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys 
        115                 120                 125


Asp Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr 
    130                 135                 140


Arg Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe 
145                 150                 155                 160


Met Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly 
                165                 170                 175


Ile Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile 
            180                 185                 190


Leu Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser 
        195                 200                 205


Thr Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu 
    210                 215                 220


Thr Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp 
225                 230                 235                 240


Thr Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val 
                245                 250                 255


Thr Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg 
            260                 265                 270


His Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu 
        275                 280                 285


Lys Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe 
    290                 295                 300


Glu Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr 
305                 310                 315                 320


Gln Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu 
                325                 330                 335


Phe Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala 
            340                 345                 350


Asp Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr 
        355                 360                 365


Ala Pro 
    370


<210>  8338
<211>  3024
<212>  DNA
<213>  Homo sapiens

<400>  8338
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaaggcaaa tctttcatct gcagttttga    600

ctctatccca atggagaaat tgttaatctt ttagtaagca ttaagaattg tatagaaaat    660

gcagaatttg tttggaagaa aagcatggat aattcatttg tgatgaatgt tgactccaca    720

aagggtttgt tcaagtattt ggagacggtt gttaaattgc cttttaagga ggactgagga    780

gggaggaagt aaaagggagc tgtgactgtg gtacgtatct gaaagcaagt gttagagagg    840

gagtggagaa cgcataagca agctggtttg accagaaaca gaactgcctg tgacagatta    900

agagacaagc aaggcttgga atctgagagc aagcaaagag agtggaaatt tacagctgcc    960

ctatcattcc atattggaag aagagatttc tacacatgaa aaaaatgcct ttgtttagta   1020

aatcacacaa aaatccagca gaaattgtga aaatcctgaa agacaatttg gccattttgg   1080

aaaagcaaga caaaaagaca gacaaggctt cagaagaagt gtctaaatca ctgcaagcaa   1140

tgaaagaaat tctgtgtggt acaaacgaga aagaaccccc aacagaagca gtggctcagc   1200

tagcacaaga actctacagc agtggcctgc tagtgacact gatagctgac ctgcagctga   1260

tagactttga gggaaaaaaa gatgtgaccc agatatttaa caacatcttg agaagacaga   1320

taggcactcg gagtcctact gtggagtata ttagtgctca tcctcatatc ctgtttatgc   1380

tcctcaaagg atatgaagcc ccacagattg ccttacgttg tgggattatg ctgagagaat   1440

gtattcgaca tgaaccactt gccaaaatca tcctcttttc taatcaattc agagatttct   1500

ttaagtacgt ggagttgtca acatttgata ttgcttcaga tgcctttgct actttcaagg   1560

atttactaac cagacataaa gtgttggtag cagacttctt agaacaaaat tacgacacta   1620

tttttgaaga ctatgagaaa ttgcttcagt ctgagaatta tgttactaag agacagtctt   1680

taaagctgct aggggagctg atcctggacc gtcacaactt tgccatcatg acaaagtata   1740

tcagcaagcc ggagaacctg aaactcatga tgaacctcct tcgggataaa agtcccaaca   1800

tccagtttga agcctttcat gtttttaagg tgtttgtggc cagtcctcac aaaacacagc   1860

ctattgtgga gatcctgtta aaaaatcagc ccaaactcat tgagtttctg agcagcttcc   1920

aaaaagaaag gacggatgat gagcagttcg ctgacgagaa gaactacttg attaaacaga   1980

tccgagactt gaagaaaacg gccccttgaa gagctccccg gcccctgtca cagtcagtcg   2040

tctcatttgt ccagtttgta cagtgtgtca tttcagaaag tcatcattct tgggaagact   2100

ttggaggtgc ctattttttc tgctgtaatt gttctgggta gatggagtat aaacatttga   2160

atggaaaaaa attaacctag aataatatat tcattttagt caagtctgtg attatttatg   2220

tgaaatgaga accattgtat cagatgttga taaaagcaat tttaacttgc agatgtgagc   2280

ccctgggcac aatgagccgc taaatgggag ctcaattgac aggcatcacc aagtcttcaa   2340

ggaggactga gttctcaggg gagaactggg aatggggcca gggtgcaaaa atgctttgcc   2400

catctgtagg tagacacaca gatcgctcag ggcactgaga gatcccagaa ggtaacgtta   2460

atgttttcag tcattgtgtg tcctttgttg ctgccaatgt ctttggactg taatcagtgc   2520

atccacacct cccaggatcc agtgctccct ctcagctcag tctcccctct ctccctgtcc   2580

tgcattccat cccagctcct cagcatggcc tcagtgggcg cacccatgcc tcccgcagtc   2640

caggtgagca ggggagcaac tgagcaggaa gaggatggat caacaagggt cacggggaat   2700

aggggaccca cggggtgtga cctgcttgct agagaactgt gaacatgtgg ctctggatag   2760

agtgactgct gctccatatt agcttccaga gggtgagtga gggacagaat atttccttca   2820

taatggtcat gggtgaatgc tttctgctgt aagtgtcttt tagagtagga atcagcatag   2880

tgggatgccc agcaggcaca aaccatgggt ccagggagtc tcagcgggga acttctatca   2940

gtatcaataa ccattggaag gagaaatgat tcatgtgtga aaaaattctc agatccatca   3000

ataaattttt ttcagagcca ttgt                                          3024


<210>  8339
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8339

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8340
<211>  2635
<212>  DNA
<213>  Homo sapiens

<400>  8340
atttactagc cttcatctca accacaacag tcccgccctg cctctaccgg ggatgaggga     60

aggcgtaacc tccgccgggg accaggccga cctacctaaa ccgatcacta catgggagga    120

gtcggacgcc ggccgtccca ccacccagcc aggagcccat tgattggtcg cactccccac    180

tggttcacgc ctcagagact cggcgcactt accgctggca ccgcagtggc gcccgagcgc    240

gccgcctccc gattgactgc tagcgctctc ggcttgtctc gcgcactgta gctgagccaa    300

tggagttact cgtagtcgag aggccggcat cactggagtg gtggcgcagc tgtttcctcc    360

ggatatccat caaatattga gaagaaagaa tatcaggagc aaagtgttct aagttgctgt    420

tcagaacgta aagatgcgaa ccccaaatca gtggtttgtt cattcttcat gcaagagcaa    480

tgcactaaag gagagaagca agctgtggtg atcagtgact ttggtgaaag ctaagaaggt    540

tcaaacaaat ttgcaaatga tatacaactt ctaagcattc catattggaa gaagagattt    600

ctacacatga aaaaaatgcc tttgtttagt aaatcacaca aaaatccagc agaaattgtg    660

aaaatcctga aagacaattt ggccattttg gaaaagcaag acaaaaagac agacaaggct    720

tcagaagaag tgtctaaatc actgcaagca atgaaagaaa ttctgtgtgg tacaaacgag    780

aaagaacccc caacagaagc agtggctcag ctagcacaag aactctacag cagtggcctg    840

ctagtgacac tgatagctga cctgcagctg atagactttg agggaaaaaa agatgtgacc    900

cagatattta acaacatctt gagaagacag ataggcactc ggagtcctac tgtggagtat    960

attagtgctc atcctcatat cctgtttatg ctcctcaaag gatatgaagc cccacagatt   1020

gccttacgtt gtgggattat gctgagagaa tgtattcgac atgaaccact tgccaaaatc   1080

atcctctttt ctaatcaatt cagagatttc tttaagtacg tggagttgtc aacatttgat   1140

attgcttcag atgcctttgc tactttcaag gatttactaa ccagacataa agtgttggta   1200

gcagacttct tagaacaaaa ttacgacact atttttgaag actatgagaa attgcttcag   1260

tctgagaatt atgttactaa gagacagtct ttaaagctgc taggggagct gatcctggac   1320

cgtcacaact ttgccatcat gacaaagtat atcagcaagc cggagaacct gaaactcatg   1380

atgaacctcc ttcgggataa aagtcccaac atccagtttg aagcctttca tgtttttaag   1440

gtgtttgtgg ccagtcctca caaaacacag cctattgtgg agatcctgtt aaaaaatcag   1500

cccaaactca ttgagtttct gagcagcttc caaaaagaaa ggacggatga tgagcagttc   1560

gctgacgaga agaactactt gattaaacag atccgagact tgaagaaaac ggccccttga   1620

agagctcccc ggcccctgtc acagtcagtc gtctcatttg tccagtttgt acagtgtgtc   1680

atttcagaaa gtcatcattc ttgggaagac tttggaggtg cctatttttt ctgctgtaat   1740

tgttctgggt agatggagta taaacatttg aatggaaaaa aattaaccta gaataatata   1800

ttcattttag tcaagtctgt gattatttat gtgaaatgag aaccattgta tcagatgttg   1860

ataaaagcaa ttttaacttg cagatgtgag cccctgggca caatgagccg ctaaatggga   1920

gctcaattga caggcatcac caagtcttca aggaggactg agttctcagg ggagaactgg   1980

gaatggggcc agggtgcaaa aatgctttgc ccatctgtag gtagacacac agatcgctca   2040

gggcactgag agatcccaga aggtaacgtt aatgttttca gtcattgtgt gtcctttgtt   2100

gctgccaatg tctttggact gtaatcagtg catccacacc tcccaggatc cagtgctccc   2160

tctcagctca gtctcccctc tctccctgtc ctgcattcca tcccagctcc tcagcatggc   2220

ctcagtgggc gcacccatgc ctcccgcagt ccaggtgagc aggggagcaa ctgagcagga   2280

agaggatgga tcaacaaggg tcacggggaa taggggaccc acggggtgtg acctgcttgc   2340

tagagaactg tgaacatgtg gctctggata gagtgactgc tgctccatat tagcttccag   2400

agggtgagtg agggacagaa tatttccttc ataatggtca tgggtgaatg ctttctgctg   2460

taagtgtctt ttagagtagg aatcagcata gtgggatgcc cagcaggcac aaaccatggg   2520

tccagggagt ctcagcgggg aacttctatc agtatcaata accattggaa ggagaaatga   2580

ttcatgtgtg aaaaaattct cagatccatc aataaatttt tttcagagcc attgt        2635


<210>  8341
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8341

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8342
<211>  918
<212>  DNA
<213>  Homo sapiens

<400>  8342
gagtatatct aagtgtttca gaatacactc aaattccaga atacgtctgc aatagtgcca     60

ggcacatagt agatcttcag tggatattga atgaatcgtg acaaatgata tgaagcccca    120

cagattgcct tacgttgtgg gattatgctg agagaatgta ttcgacatga accacttgcc    180

aaaatcatcc tcttttctaa tcaattcaga gatttcttta agtacgtgga gttgtcaaca    240

tttgatattg cttcagatgc ctttgctact ttcaaggatt tactaaccag acataaagtg    300

ttggtagcag acttcttaga acaaaattac gacactattt ttgaagacta tgagaaattg    360

cttcagtctg agaattatgt tactaagaga cagtctttaa agctgctagg ggagctgatc    420

ctggaccgtc acaactttgc catcatgaca aagtatatca gcaagccgga gaacctgaaa    480

ctcatgatga acctccttcg ggataaaagt cccaacatcc agtttgaagc ctttcatgtt    540

tttaaggtgt ttgtggccag tcctcacaaa acacagccta ttgtggagat cctgttaaaa    600

aatcagccca aactcattga gtttctgagc agcttccaaa aagaaaggac ggatgatgag    660

cagttcgctg acgagaagaa ctacttgatt aaacagatcc gagacttgaa gaaaacggcc    720

ccttgaagag ctccccggcc cctgtcacag tcagtcgtct catttgtcca gtttgtacag    780

tgtgtcattt cagaaagtca tcattcttgg gaagactttg gaggtgccta ttttttctgc    840

tgtaattgtt ctgggtagat ggagtataaa catttgaatg gaaaaaaatt aacctagaat    900

aatatattca ttttagtc                                                  918


<210>  8343
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  8343

Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
1               5                   10                  15


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
            20                  25                  30


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
        35                  40                  45


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
    50                  55                  60


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
65                  70                  75                  80


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
                85                  90                  95


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
            100                 105                 110


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
        115                 120                 125


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
    130                 135                 140


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
145                 150                 155                 160


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
                165                 170                 175


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
            180                 185                 190


Pro 



<210>  8344
<211>  1704
<212>  DNA
<213>  Homo sapiens

<400>  8344
gtgacgttac aggactgagg agggaggaag taaaagggag ctgtgactgt ggtacgtatc     60

tgaaagcaag tgttagagag ggagtggaga acgcataagc aagctggttt gaccagaaac    120

agaactgcct gtgacagatt aagagacaag caaggcttgg aatctgagag caagcaaaga    180

gagtggaaat ttacagctgc cctatgtgag tgttcaagtg atcattttct ggtaacgttt    240

tccagtggta actgttactc ttcaaaaaga gggacagaaa gtcaagacct aattgtggaa    300

actcttttct ctgccacgct tggtaatagg aggcaacctc tattaaatgg acgataaagg    360

ctacttcatc taaagtgctt tgagctcaag aaagagctgt cttcagcacc tcaccatgtg    420

tctacatttt gttgcttaga aaagcctagg catttctgta acatttgcat tccatattgg    480

aagaagagat ttctacacat gaaaaaaatg cctttgttta gtaaatcaca caaaaatcca    540

gcagaaattg tgaaaatcct gaaagacaat ttggccattt tggaaaagca agacaaaaag    600

acagacaagg cttcagaaga agtgtctaaa tcactgcaag caatgaaaga aattctgtgt    660

ggtacaaacg agaaagaacc cccaacagaa gcagtggctc agctagcaca agaactctac    720

agcagtggcc tgctagtgac actgatagct gacctgcagc tgatagactt tgagggaaaa    780

aaagatgtga cccagatatt taacaacatc ttgagaagac agataggcac tcggagtcct    840

actgtggagt atattagtgc tcatcctcat atcctgttta tgctcctcaa aggatatgaa    900

gccccacaga ttgccttacg ttgtgggatt atgctgagag aatgtattcg acatgaacca    960

cttgccaaaa tcatcctctt ttctaatcaa ttcagagatt tctttaagta cgtggagttg   1020

tcaacatttg atattgcttc agatgccttt gctactttca aggatttact aaccagacat   1080

aaagtgttgg tagcagactt cttagaacaa aattacgaca ctatttttga agactatgag   1140

aaattgcttc agtctgagaa ttatgttact aagagacagt ctttaaagct gctaggggag   1200

ctgatcctgg accgtcacaa ctttgccatc atgacaaagt atatcagcaa gccggagaac   1260

ctgaaactca tgatgaacct ccttcgggat aaaagtccca acatccagtt tgaagccttt   1320

catgttttta aggtgtttgt ggccagtcct cacaaaacac agcctattgt ggagatcctg   1380

ttaaaaaatc agcccaaact cattgagttt ctgagcagct tccaaaaaga aaggacggat   1440

gatgagcagt tcgctgacga gaagaactac ttgattaaac agatccgaga cttgaagaaa   1500

acggcccctt gaagagctcc ccggcccctg tcacagtcag tcgtctcatt tgtccagttt   1560

gtacagtgtg tcatttcaga aagtcatcat tcttgggaag actttggagg tgcctatttt   1620

ttctgctgta attgttctgg gtagatggag tataaacatt tgaatggaaa aaaattaacc   1680

tagaataata tattcatttt agtc                                          1704


<210>  8345
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8345

Met Lys Lys Met Pro Leu Phe Ser Lys Ser His Lys Asn Pro Ala Glu 
1               5                   10                  15


Ile Val Lys Ile Leu Lys Asp Asn Leu Ala Ile Leu Glu Lys Gln Asp 
            20                  25                  30


Lys Lys Thr Asp Lys Ala Ser Glu Glu Val Ser Lys Ser Leu Gln Ala 
        35                  40                  45


Met Lys Glu Ile Leu Cys Gly Thr Asn Glu Lys Glu Pro Pro Thr Glu 
    50                  55                  60


Ala Val Ala Gln Leu Ala Gln Glu Leu Tyr Ser Ser Gly Leu Leu Val 
65                  70                  75                  80


Thr Leu Ile Ala Asp Leu Gln Leu Ile Asp Phe Glu Gly Lys Lys Asp 
                85                  90                  95


Val Thr Gln Ile Phe Asn Asn Ile Leu Arg Arg Gln Ile Gly Thr Arg 
            100                 105                 110


Ser Pro Thr Val Glu Tyr Ile Ser Ala His Pro His Ile Leu Phe Met 
        115                 120                 125


Leu Leu Lys Gly Tyr Glu Ala Pro Gln Ile Ala Leu Arg Cys Gly Ile 
    130                 135                 140


Met Leu Arg Glu Cys Ile Arg His Glu Pro Leu Ala Lys Ile Ile Leu 
145                 150                 155                 160


Phe Ser Asn Gln Phe Arg Asp Phe Phe Lys Tyr Val Glu Leu Ser Thr 
                165                 170                 175


Phe Asp Ile Ala Ser Asp Ala Phe Ala Thr Phe Lys Asp Leu Leu Thr 
            180                 185                 190


Arg His Lys Val Leu Val Ala Asp Phe Leu Glu Gln Asn Tyr Asp Thr 
        195                 200                 205


Ile Phe Glu Asp Tyr Glu Lys Leu Leu Gln Ser Glu Asn Tyr Val Thr 
    210                 215                 220


Lys Arg Gln Ser Leu Lys Leu Leu Gly Glu Leu Ile Leu Asp Arg His 
225                 230                 235                 240


Asn Phe Ala Ile Met Thr Lys Tyr Ile Ser Lys Pro Glu Asn Leu Lys 
                245                 250                 255


Leu Met Met Asn Leu Leu Arg Asp Lys Ser Pro Asn Ile Gln Phe Glu 
            260                 265                 270


Ala Phe His Val Phe Lys Val Phe Val Ala Ser Pro His Lys Thr Gln 
        275                 280                 285


Pro Ile Val Glu Ile Leu Leu Lys Asn Gln Pro Lys Leu Ile Glu Phe 
    290                 295                 300


Leu Ser Ser Phe Gln Lys Glu Arg Thr Asp Asp Glu Gln Phe Ala Asp 
305                 310                 315                 320


Glu Lys Asn Tyr Leu Ile Lys Gln Ile Arg Asp Leu Lys Lys Thr Ala 
                325                 330                 335


Pro 



<210>  8346
<211>  601
<212>  DNA
<213>  Homo sapiens

<400>  8346
attctgatta tcttggtgga atcttggaaa agctaagcag cttcactctt aataaacaga     60

ccttgatcag caacaagtag tgcagaggga gctccttaca actcgaccag tgaacccaat    120

ttgagaactg aaggagaaat caatatctat gcagatcagt tccacaggga agacatccta    180

tggggactgt ttcttcctgg gatgagtaga atggaagccc tatgcataat tcagttcgtg    240

gagaagagca aaggctggac tcatggtccc aatttggagg tgaagcatgg tgacaaacgt    300

caatgggaag catacacatt gcaaagtggc ttctctcagc gtctgctgta aacaccgggt    360

cgtgagttgt ctgtgagtgt atgaatgaaa acattccata gagattgtgt ggccataata    420

cacaaggagc tggactccag caaatggccc agatcaacat tctgaaattg aacttagaaa    480

actatcagat atctggaagt gaagtaaagc ttatgaagaa aaaagcagtg tggaactgca    540

gtgatttaaa agaaacaaga tgggacccat acactcagca ttaaaacata taaatctgta    600

a                                                                    601


<210>  8347
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  8347

Met Ser Arg Met Glu Ala Leu Cys Ile Ile Gln Phe Val Glu Lys Ser 
1               5                   10                  15


Lys Gly Trp Thr His Gly Pro Asn Leu Glu Val Lys His Gly Asp Lys 
            20                  25                  30


Arg Gln Trp Glu Ala Tyr Thr Leu Gln Ser Gly Phe Ser Gln Arg Leu 
        35                  40                  45


Leu 



<210>  8348
<211>  1952
<212>  DNA
<213>  Homo sapiens

<400>  8348
gagcagtctc cggaagctgc ctctggctgc tctgttaacg tgtcccgcga gcgaggcgcg     60

tcgcaaaagg tcgcggcgga acttccctgc gcttttcaga ccatactctt tacggtacta    120

ggcactgctg agctgggaga tgtcggcggc gtgttgggag gaaccgtggg gtcttcccgg    180

cggctttgcg aagcgggtcc tggtgaccgg cggtgctggt ttcattgcat cacatatgat    240

tgtctcttta gtggaagatt atccaaacta tatgatcata aatctagaca agctggatta    300

ctgtgcaagc ttgaagaatc ttgaaaccat ttctaacaaa cagaactaca aatttataca    360

gggtgacata tgtgattctc actttgtgaa actgcttttt gaaacagaga aaatagatat    420

agtactacat tttgccgcac aaacacatgt agatctttca ttcgtacgtg cctttgagtt    480

tacctatgtt aatgtttatg gcactcacgt tttggtaagt gctgctcatg aagccagagt    540

ggagaagttt atttatgtca gcacagatga agtatatggt ggcagtcttg ataaggaatt    600

tgatgaatct tcacccaaac aacctacaaa tccttatgca tcatctaaag cagctgctga    660

atgttttgta cagtcttact gggaacaata taagtttcca gttgtcatca caagaagcag    720

taatgtttat ggaccacatc aatatccaga aaaggttatt ccaaaattta tatctttgct    780

acagcacaac aggaaatgtt gcattcatgg gtcagggctt caaacaagaa acttccttta    840

tgctactgat gttgtagaag catttctcac tgtcctcaaa aaagggaaac caggtgaaat    900

ttataacatc ggaaccaatt ttgaaatgtc agttgtccag cttgccaaag aactaataca    960

actgatcaaa gagaccaatt cagagtctga aatggaaaat tgggttgatt atgttaatga   1020

tagacccacc aatgacatga gatacccaat gaagtcagaa aaaatacatg gcttaggatg   1080

gagacctaaa gtgccttgga aagaaggaat aaagaaaaca attgaatggt acagagagaa   1140

ttttcacaac tggaagaatg tggaaaaggc attagaaccc tttccggtat aatcaccatt   1200

tatatagtcg agacagttgt caaagaagaa agttatccta cctcgccaag tggtatgaaa   1260

ttaagtgacc aaatgaagtg cactcttttc ttttggaatt agattcatga ctttctgtat   1320

aaaattcaaa tgcagaatgc ctcaatcttt gggagagttt cagtactggc atagaattta   1380

aatgtcaaaa ttctttctga aaccctttct cctagaaact aggaaataat aggtgtagaa   1440

gactctccct aagggtagcc aggaagaagt ctcctgattc ggacaaccat gaggggtagt   1500

ggtgctaggg agaaggcaac cttcactggt tttgaactca gtgcctaaga aagtctctga   1560

aatgttcgtt tttaggcaat ataggatgtc ttaggcccta attcaccatt tcttttttaa   1620

gatctgatat gctatcattg ccttaataat ggaacaaaat agaagcatat ctaacacttt   1680

ttaaattgat aattttgtaa aattgattac gttgaatgct ttttaagaga agtgtgtaaa   1740

gtttttatat tttcacaatt aacgtatgta aaaccttgta tcagaaattt atcatgttta   1800

ctgtttaaaa tgattgtatt tataaaattg tcaatatctt aatgtattta atgtagaata   1860

ttgcttttta aaataatgtt tttattttgc tgtagaaaaa taaaaaaaaa tttgattata   1920

tatttttaat ccttctttgc cctaaagact tt                                 1952


<210>  8349
<211>  350
<212>  PRT
<213>  Homo sapiens

<400>  8349

Met Ser Ala Ala Cys Trp Glu Glu Pro Trp Gly Leu Pro Gly Gly Phe 
1               5                   10                  15


Ala Lys Arg Val Leu Val Thr Gly Gly Ala Gly Phe Ile Ala Ser His 
            20                  25                  30


Met Ile Val Ser Leu Val Glu Asp Tyr Pro Asn Tyr Met Ile Ile Asn 
        35                  40                  45


Leu Asp Lys Leu Asp Tyr Cys Ala Ser Leu Lys Asn Leu Glu Thr Ile 
    50                  55                  60


Ser Asn Lys Gln Asn Tyr Lys Phe Ile Gln Gly Asp Ile Cys Asp Ser 
65                  70                  75                  80


His Phe Val Lys Leu Leu Phe Glu Thr Glu Lys Ile Asp Ile Val Leu 
                85                  90                  95


His Phe Ala Ala Gln Thr His Val Asp Leu Ser Phe Val Arg Ala Phe 
            100                 105                 110


Glu Phe Thr Tyr Val Asn Val Tyr Gly Thr His Val Leu Val Ser Ala 
        115                 120                 125


Ala His Glu Ala Arg Val Glu Lys Phe Ile Tyr Val Ser Thr Asp Glu 
    130                 135                 140


Val Tyr Gly Gly Ser Leu Asp Lys Glu Phe Asp Glu Ser Ser Pro Lys 
145                 150                 155                 160


Gln Pro Thr Asn Pro Tyr Ala Ser Ser Lys Ala Ala Ala Glu Cys Phe 
                165                 170                 175


Val Gln Ser Tyr Trp Glu Gln Tyr Lys Phe Pro Val Val Ile Thr Arg 
            180                 185                 190


Ser Ser Asn Val Tyr Gly Pro His Gln Tyr Pro Glu Lys Val Ile Pro 
        195                 200                 205


Lys Phe Ile Ser Leu Leu Gln His Asn Arg Lys Cys Cys Ile His Gly 
    210                 215                 220


Ser Gly Leu Gln Thr Arg Asn Phe Leu Tyr Ala Thr Asp Val Val Glu 
225                 230                 235                 240


Ala Phe Leu Thr Val Leu Lys Lys Gly Lys Pro Gly Glu Ile Tyr Asn 
                245                 250                 255


Ile Gly Thr Asn Phe Glu Met Ser Val Val Gln Leu Ala Lys Glu Leu 
            260                 265                 270


Ile Gln Leu Ile Lys Glu Thr Asn Ser Glu Ser Glu Met Glu Asn Trp 
        275                 280                 285


Val Asp Tyr Val Asn Asp Arg Pro Thr Asn Asp Met Arg Tyr Pro Met 
    290                 295                 300


Lys Ser Glu Lys Ile His Gly Leu Gly Trp Arg Pro Lys Val Pro Trp 
305                 310                 315                 320


Lys Glu Gly Ile Lys Lys Thr Ile Glu Trp Tyr Arg Glu Asn Phe His 
                325                 330                 335


Asn Trp Lys Asn Val Glu Lys Ala Leu Glu Pro Phe Pro Val 
            340                 345                 350


<210>  8350
<211>  1811
<212>  DNA
<213>  Homo sapiens

<400>  8350
gttaacgtgt cccgcgagcg aggcgcgtcg caaaaggtcg cggcggaact tccctgcgct     60

tttcagacca tactctttac ggtactaggc actgctgagc tgggagatgt cggcggcgtg    120

ttgggaggaa ccgtggggtc ttcccggcgg ctttgcgaag cgggtcctgg tgaccggcgg    180

tgctggtttc attgcatcac atatgattgt ctctttagtg gaagattatc caaactatat    240

gatcataaat ctagacaagc tggattactg tgcaagcttg aagaatcttg aaaccatttc    300

taacaaacag aactacaaat ttatacagat ctttcattcg tacgtgcctt tgagtttacc    360

tatgttaatg tttatggcac tcacgttttg gtaagtgctg ctcatgaagc cagagtggag    420

aagtttattt atgtcagcac agatgaagta tatggtggca gtcttgataa ggaatttgat    480

gaatcttcac ccaaacaacc tacaaatcct tatgcatcat ctaaagcagc tgctgaatgt    540

tttgtacagt cttactggga acaatataag tttccagttg tcatcacaag aagcagtaat    600

gtttatggac cacatcaata tccagaaaag gttattccaa aatttatatc tttgctacag    660

cacaacagga aatgttgcat tcatgggtca gggcttcaaa caagaaactt cctttatgct    720

actgatgttg tagaagcatt tctcactgtc ctcaaaaaag ggaaaccagg tgaaatttat    780

aacatcggaa ccaattttga aatgtcagtt gtccagcttg ccaaagaact aatacaactg    840

atcaaagaga ccaattcaga gtctgaaatg gaaaattggg ttgattatgt taatgataga    900

cccaccaatg acatgagata cccaatgaag tcagaaaaaa tacatggctt aggatggaga    960

cctaaagtgc cttggaaaga aggaataaag aaaacaattg aatggtacag agagaatttt   1020

cacaactgga agaatgtgga aaaggcatta gaaccctttc cggtataatc accatttata   1080

tagtcgagac agttgtcaaa gaagaaagtt atcctacctc gccaagtggt atgaaattaa   1140

gtgaccaaat gaagtgcact cttttctttt ggaattagat tcatgacttt ctgtataaaa   1200

ttcaaatgca gaatgcctca atctttggga gagtttcagt actggcatag aatttaaatg   1260

tcaaaattct ttctgaaacc ctttctccta gaaactagga aataataggt gtagaagact   1320

ctccctaagg gtagccagga agaagtctcc tgattcggac aaccatgagg ggtagtggtg   1380

ctagggagaa ggcaaccttc actggttttg aactcagtgc ctaagaaagt ctctgaaatg   1440

ttcgttttta ggcaatatag gatgtcttag gccctaattc accatttctt ttttaagatc   1500

tgatatgcta tcattgcctt aataatggaa caaaatagaa gcatatctaa cactttttaa   1560

attgataatt ttgtaaaatt gattacgttg aatgcttttt aagagaagtg tgtaaagttt   1620

ttatattttc acaattaacg tatgtaaaac cttgtatcag aaatttatca tgtttactgt   1680

ttaaaatgat tgtatttata aaattgtcaa tatcttaatg tatttaatgt agaatattgc   1740

tttttaaaat aatgttttta ttttgctgta gaaaaataaa aaaaaatttg attatatatt   1800

tttaatcctt c                                                        1811


<210>  8351
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  8351

Met Lys Pro Glu Trp Arg Ser Leu Phe Met Ser Ala Gln Met Lys Tyr 
1               5                   10                  15


Met Val Ala Val Leu Ile Arg Asn Leu Met Asn Leu His Pro Asn Asn 
            20                  25                  30


Leu Gln Ile Leu Met His His Leu Lys Gln Leu Leu Asn Val Leu Tyr 
        35                  40                  45


Ser Leu Thr Gly Asn Asn Ile Ser Phe Gln Leu Ser Ser Gln Glu Ala 
    50                  55                  60


Val Met Phe Met Asp His Ile Asn Ile Gln Lys Arg Leu Phe Gln Asn 
65                  70                  75                  80


Leu Tyr Leu Cys Tyr Ser Thr Thr Gly Asn Val Ala Phe Met Gly Gln 
                85                  90                  95


Gly Phe Lys Gln Glu Thr Ser Phe Met Leu Leu Met Leu 
            100                 105


<210>  8352
<211>  1795
<212>  DNA
<213>  Homo sapiens

<400>  8352
gttaacgtgt cccgcgagcg aggcgcgtcg caaaaggtcg cggcggaact tccctgcgct     60

tttcagacca tactctttac ggtactaggc actgctgagc tgggagatgt cggcggcgtg    120

ttgggaggaa ccgtggggtc ttcccggcgg ctttgcgaag cgggtcctgg tgaccggcgg    180

tgctggtttc attgcatcac atatgattgt ctctttagtg gaagattatc caaactatat    240

gatcataaat ctagacaagc tggattactg tgcaagcttg aagaatcttg aaaccatttc    300

taacaaacag aactacaaat ttatacagat ctttcattcg tacgtgcctt tgagtttacc    360

tatgttaatg tttatggcac tcacgttttg gtaagtgctg ctcatgaagc cagagtggag    420

aagtttattt atgtcagcac agatgaagta tatggtggca gtcttgataa ggaatttgat    480

gaatcttcac ccaaacaacc tacaaatcct tatgcatcat ctaaagcagc tgctgaatgt    540

tttgtacagt cttactggga acaatataag tttccagttg tcatcacaag aagcagtaat    600

gtttatggac cacatcaata tccagaaaag gttattccaa aatttatatc tttgctacag    660

cacaacagga aatgttgcat tcatgggtca gggcttcaaa caagaaactt cctttatgct    720

actgatgttg tagaagcatt tctcactgtc ctcaaaaaag ggaaaccagg tgaaatttat    780

aacatcggaa ccaattttga aatgtcagtt gtccagcttg ccaaagaact aatacaactg    840

atcaaagaga ccaattcaga gtctgaaatg gaaaattggg ttgattatgt taatgataga    900

cccaccaatg acatgagata cccaatgaag tcagaaaaaa tacatggctt aggatggaga    960

cctaaagtgc cttggaaaga aggaataaag aaaacaattg aatggtacag agagaatttt   1020

cacaactgga agaatgtgga aaaggcatta gaaccctttc cggtataatc accatttata   1080

tagtcgagac agttgtcaaa gaagaaagtt atcctacctc gccaagtggt atgaaattaa   1140

gtgaccaaat gaagtgcact cttttctttt ggaattagat tcatgacttt ctgtataaaa   1200

ttcaaatgca gaatgcctca atctttggga gagtttcagt actggcatag aatttaaatg   1260

tcaaaattct ttctgaaacc ctttctccta gaaactagga aataataggt gtagaagact   1320

ctccctaagg gtagccagga agaagtctcc tgattcggac aaccatgagg ggtagtggtg   1380

ctagggagaa ggcaaccttc actggttttg aactcagtgc ctaagaaagt ctctgaaatg   1440

ttcgttttta ggcaatatag gatgtcttag gccctaattc accatttctt ttttaagatc   1500

tgatatgcta tcattgcctt aataatggaa caaaatagaa gcatatctaa cactttttaa   1560

attgataatt ttgtaaaatt gattacgttg aatgcttttt aagagaagtg tgtaaagttt   1620

ttatattttc acaattaacg tatgtaaaac cttgtatcag aaatttatca tgtttactgt   1680

ttaaaatgat tgtatttata aaattgtcaa tatcttaatg tatttaatgt agaatattgc   1740

tttttaaaat aatgttttta ttttgctgta gaaaaataaa aaaaaatttg attat        1795


<210>  8353
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  8353

Met Lys Pro Glu Trp Arg Ser Leu Phe Met Ser Ala Gln Met Lys Tyr 
1               5                   10                  15


Met Val Ala Val Leu Ile Arg Asn Leu Met Asn Leu His Pro Asn Asn 
            20                  25                  30


Leu Gln Ile Leu Met His His Leu Lys Gln Leu Leu Asn Val Leu Tyr 
        35                  40                  45


Ser Leu Thr Gly Asn Asn Ile Ser Phe Gln Leu Ser Ser Gln Glu Ala 
    50                  55                  60


Val Met Phe Met Asp His Ile Asn Ile Gln Lys Arg Leu Phe Gln Asn 
65                  70                  75                  80


Leu Tyr Leu Cys Tyr Ser Thr Thr Gly Asn Val Ala Phe Met Gly Gln 
                85                  90                  95


Gly Phe Lys Gln Glu Thr Ser Phe Met Leu Leu Met Leu 
            100                 105


<210>  8354
<211>  1919
<212>  DNA
<213>  Homo sapiens

<400>  8354
gagcagtctc cggaagctgc ctctggctgc tctgttaacg tgtcccgcga gcgaggcgcg     60

tcgcaaaagg tcgcggcgga acttccctgc gcttttcaga ccatactctt tacggtacta    120

ggcactgctg agctgggaga tgtcggcggc gtgttgggag gaaccgtggg gtcttcccgg    180

cggctttgcg aagcgggtcc tggtgaccgg cggtgctggt ttcattgcat cacatatgat    240

tgtctcttta gtggaagatt atccaaacta tatgatcata aatctagaca agctggatta    300

ctgtgcaagc ttgaagaatc ttgaaaccat ttctaacaaa cagaactaca aatttataca    360

gggtgacata tgtgattctc actttgtgaa actgcttttt gaaacagaga aaatagatat    420

agtactacat tttgccgcac aaacacatgt agatctttca ttcgtacgtg cctttgagtt    480

tacctatgtt aatgtttatg gcactcacgt tttggtaagt gctgctcatg aagccagagt    540

ggagaagttt atttatgtca gcacagatga agtatatggt ggcagtcttg ataaggaatt    600

tgatgaatct tcacccaaac aacctacaaa tccttatgca tcatctaaag cagctgctga    660

atgttttgta cagtcttact gggaacaata taagtttcca gttgtcatca caagaagcag    720

taatgtttat ggaccacatc aatatccaga aaaggttatt ccaaaattta tatctttgct    780

acagcacaac aggaaatgtt gcattcatgg gtcagggctt caaacaagaa acttccttta    840

tgctactgat gttgtagaag catttctcac tgtcctcaaa aaagggaaac caggtgaaat    900

ttataacatc ggaaccaatt ttgaaatgtc agttgtccag cttgccaaag aactaataca    960

actgatcaaa gagaccaatt cagagtctga aatggaaaat tgggttgatt atgttaatga   1020

tagacccacc aatgacatga gatacccaat gaagtcagaa aaaatacatg gcttaggatg   1080

gagacctaaa gtgccttgga aagaaggaat aaagaaaaca attgaatggt acagagagaa   1140

ttttcacaac tggaagaatg tggaaaaggc attagaaccc tttccggtat aatcaccatt   1200

tatatagtcg agacagttgt caaagaagaa agttatccta cctcgccaag tggtatgaaa   1260

ttaagtgacc aaatgaagtg cactcttttc ttttggaatt agattcatga ctttctgtat   1320

aaaattcaaa tgcagaatgc ctcaatcttt gggagagttt cagtactggc atagaattta   1380

aatgtcaaaa ttctttctga aaccctttct cctagaaact aggaaataat aggtgtagaa   1440

gactctccct aagggtagcc aggaagaagt ctcctgattc ggacaaccat gaggggtagt   1500

ggtgctaggg agaaggcaac cttcactggt tttgaactca gtgcctaaga aagtctctga   1560

aatgttcgtt tttaggcaat ataggatgtc ttaggcccta attcaccatt tcttttttaa   1620

gatctgatat gctatcattg ccttaataat ggaacaaaat agaagcatat ctaacacttt   1680

ttaaattgat aattttgtaa aattgattac gttgaatgct ttttaagaga agtgtgtaaa   1740

gtttttatat tttcacaatt aacgtatgta aaaccttgta tcagaaattt atcatgttta   1800

ctgtttaaaa tgattgtatt tataaaattg tcaatatctt aatgtattta atgtagaata   1860

ttgcttttta aaataatgtt tttattttgc tgtagaaaaa taaaaaaaaa tttgattat    1919


<210>  8355
<211>  350
<212>  PRT
<213>  Homo sapiens

<400>  8355

Met Ser Ala Ala Cys Trp Glu Glu Pro Trp Gly Leu Pro Gly Gly Phe 
1               5                   10                  15


Ala Lys Arg Val Leu Val Thr Gly Gly Ala Gly Phe Ile Ala Ser His 
            20                  25                  30


Met Ile Val Ser Leu Val Glu Asp Tyr Pro Asn Tyr Met Ile Ile Asn 
        35                  40                  45


Leu Asp Lys Leu Asp Tyr Cys Ala Ser Leu Lys Asn Leu Glu Thr Ile 
    50                  55                  60


Ser Asn Lys Gln Asn Tyr Lys Phe Ile Gln Gly Asp Ile Cys Asp Ser 
65                  70                  75                  80


His Phe Val Lys Leu Leu Phe Glu Thr Glu Lys Ile Asp Ile Val Leu 
                85                  90                  95


His Phe Ala Ala Gln Thr His Val Asp Leu Ser Phe Val Arg Ala Phe 
            100                 105                 110


Glu Phe Thr Tyr Val Asn Val Tyr Gly Thr His Val Leu Val Ser Ala 
        115                 120                 125


Ala His Glu Ala Arg Val Glu Lys Phe Ile Tyr Val Ser Thr Asp Glu 
    130                 135                 140


Val Tyr Gly Gly Ser Leu Asp Lys Glu Phe Asp Glu Ser Ser Pro Lys 
145                 150                 155                 160


Gln Pro Thr Asn Pro Tyr Ala Ser Ser Lys Ala Ala Ala Glu Cys Phe 
                165                 170                 175


Val Gln Ser Tyr Trp Glu Gln Tyr Lys Phe Pro Val Val Ile Thr Arg 
            180                 185                 190


Ser Ser Asn Val Tyr Gly Pro His Gln Tyr Pro Glu Lys Val Ile Pro 
        195                 200                 205


Lys Phe Ile Ser Leu Leu Gln His Asn Arg Lys Cys Cys Ile His Gly 
    210                 215                 220


Ser Gly Leu Gln Thr Arg Asn Phe Leu Tyr Ala Thr Asp Val Val Glu 
225                 230                 235                 240


Ala Phe Leu Thr Val Leu Lys Lys Gly Lys Pro Gly Glu Ile Tyr Asn 
                245                 250                 255


Ile Gly Thr Asn Phe Glu Met Ser Val Val Gln Leu Ala Lys Glu Leu 
            260                 265                 270


Ile Gln Leu Ile Lys Glu Thr Asn Ser Glu Ser Glu Met Glu Asn Trp 
        275                 280                 285


Val Asp Tyr Val Asn Asp Arg Pro Thr Asn Asp Met Arg Tyr Pro Met 
    290                 295                 300


Lys Ser Glu Lys Ile His Gly Leu Gly Trp Arg Pro Lys Val Pro Trp 
305                 310                 315                 320


Lys Glu Gly Ile Lys Lys Thr Ile Glu Trp Tyr Arg Glu Asn Phe His 
                325                 330                 335


Asn Trp Lys Asn Val Glu Lys Ala Leu Glu Pro Phe Pro Val 
            340                 345                 350


<210>  8356
<211>  717
<212>  DNA
<213>  Homo sapiens

<400>  8356
atgccccact aaatttaaga atcatttctc cagtgtaata gtttttaaaa taatctgtat     60

cttattttta taattgttga gataatttca gatcttaatg acctatcata gaactttgaa    120

ttatagcatt aaaatttgaa atctattttt atataatttt actttctcaa aggacttatt    180

taattcatag aactgtagat atttctttaa aatgaactta tgacataaaa ttgaatacac    240

atttcacagg ggtcactttc ctactgagtc ccctcagaag gtttggagat taagaaatat    300

gaacaaaatt tagaaaagct acgagaattt gtattttcag taaagattct gggatcccca    360

tgggaattag cttctctgga gttgtagtac ccagtcaatg ctttaggaga gtttaccttt    420

ttacacttta tgatttcact tcgtttaatc tctttagttg cattcatggg tcagggcttc    480

aaacaagaaa cttcctttat gctactgatg ttgtagaagc atttctcact gtcctcaaaa    540

aagggaaacc aggtgaaatt tataacatcg gaaccaattt tgaaatgtca gttgtccagc    600

ttgccaaaga actaatacaa ctgatcaaag agaccaattc agagtctgaa atggaaaatt    660

gggttgatta tgttaatgat agacccacca atgacatgag atacccaatg aagtcag       717


<210>  8357
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  8357

Met Gly Ile Ser Phe Ser Gly Val Val Val Pro Ser Gln Cys Phe Arg 
1               5                   10                  15


Arg Val Tyr Leu Phe Thr Leu Tyr Asp Phe Thr Ser Phe Asn Leu Phe 
            20                  25                  30


Ser Cys Ile His Gly Ser Gly Leu Gln Thr Arg Asn Phe Leu Tyr Ala 
        35                  40                  45


Thr Asp Val Val Glu Ala Phe Leu Thr Val Leu Lys Lys Gly Lys Pro 
    50                  55                  60


Gly Glu Ile Tyr Asn Ile Gly Thr Asn Phe Glu Met Ser Val Val Gln 
65                  70                  75                  80


Leu Ala Lys Glu Leu Ile Gln Leu Ile Lys Glu Thr Asn Ser Glu Ser 
                85                  90                  95


Glu Met Glu Asn Trp Val Asp Tyr Val Asn Asp Arg Pro Thr Asn Asp 
            100                 105                 110


Met Arg Tyr Pro Met Lys 
        115


<210>  8358
<211>  1056
<212>  DNA
<213>  Homo sapiens

<400>  8358
gagcagtctc cggaagctgc ctctggctgc tctgttaacg tgtcccgcga gcgaggcgcg     60

tcgcaaaagg tcgcggcgga acttccctgc gcttttcaga ccatactctt tacggtacta    120

ggcactgctg agctgggaga tgtcggcggc gtgttgggag gaaccgtggg gtcttcccgg    180

cggctttgcg aagcgggtcc tggtgaccgg cggtgctggt ttcattgcat cacatatgat    240

tgtctcttta gtggaagatt atccaaacta tatgatcata aatctagaca agctggatta    300

ctgtgcaagc ttgaagaatc ttgaaaccat ttctaacaaa cagaactaca aatttataca    360

gggtgacata tgtgattctc actttgtgaa actgcttttt gaaacagaga aaatagatat    420

agtactacat tttgccgcac aaacacatgt agatctttca ttcgtacgtg cctttgagtt    480

tacctatgtt aatgtttatg gcactcacgt tttggtaagt gctgctcatg aagccagagt    540

ggagaagttt atttatgtca gcacagatga agtatatggt ggcagtcttg ataaggaatt    600

tgatgaatct tcacccaaac aacctacaaa tccttatgca tcatctaaag cagctgctga    660

atgttttgta cagtcttact gggaacaata taagtttcca gttgtcatca caagaagcag    720

taatgtttat ggaccacatc aatatccaga aaaggttatt ccaaaattta tatctttgct    780

acagcacaac aggaaatgtt gcattcatgg gtcagggctt caaacaagaa acttccttta    840

tgctactgat gttgtagaag catttctcac tgtcctcaaa aaagggaaac caggtgaaat    900

ttataacatc ggaaccaatt ttgaaatgtc agttgtccag cttgccaaag aactaataca    960

actgatcaaa gagaccaatt cagagtctga aatggaaaat tgggttgatt atgttaatga   1020

tagacccacc aatgacatga gatacccaat gaagtc                             1056


<210>  8359
<211>  304
<212>  PRT
<213>  Homo sapiens

<400>  8359

Met Ser Ala Ala Cys Trp Glu Glu Pro Trp Gly Leu Pro Gly Gly Phe 
1               5                   10                  15


Ala Lys Arg Val Leu Val Thr Gly Gly Ala Gly Phe Ile Ala Ser His 
            20                  25                  30


Met Ile Val Ser Leu Val Glu Asp Tyr Pro Asn Tyr Met Ile Ile Asn 
        35                  40                  45


Leu Asp Lys Leu Asp Tyr Cys Ala Ser Leu Lys Asn Leu Glu Thr Ile 
    50                  55                  60


Ser Asn Lys Gln Asn Tyr Lys Phe Ile Gln Gly Asp Ile Cys Asp Ser 
65                  70                  75                  80


His Phe Val Lys Leu Leu Phe Glu Thr Glu Lys Ile Asp Ile Val Leu 
                85                  90                  95


His Phe Ala Ala Gln Thr His Val Asp Leu Ser Phe Val Arg Ala Phe 
            100                 105                 110


Glu Phe Thr Tyr Val Asn Val Tyr Gly Thr His Val Leu Val Ser Ala 
        115                 120                 125


Ala His Glu Ala Arg Val Glu Lys Phe Ile Tyr Val Ser Thr Asp Glu 
    130                 135                 140


Val Tyr Gly Gly Ser Leu Asp Lys Glu Phe Asp Glu Ser Ser Pro Lys 
145                 150                 155                 160


Gln Pro Thr Asn Pro Tyr Ala Ser Ser Lys Ala Ala Ala Glu Cys Phe 
                165                 170                 175


Val Gln Ser Tyr Trp Glu Gln Tyr Lys Phe Pro Val Val Ile Thr Arg 
            180                 185                 190


Ser Ser Asn Val Tyr Gly Pro His Gln Tyr Pro Glu Lys Val Ile Pro 
        195                 200                 205


Lys Phe Ile Ser Leu Leu Gln His Asn Arg Lys Cys Cys Ile His Gly 
    210                 215                 220


Ser Gly Leu Gln Thr Arg Asn Phe Leu Tyr Ala Thr Asp Val Val Glu 
225                 230                 235                 240


Ala Phe Leu Thr Val Leu Lys Lys Gly Lys Pro Gly Glu Ile Tyr Asn 
                245                 250                 255


Ile Gly Thr Asn Phe Glu Met Ser Val Val Gln Leu Ala Lys Glu Leu 
            260                 265                 270


Ile Gln Leu Ile Lys Glu Thr Asn Ser Glu Ser Glu Met Glu Asn Trp 
        275                 280                 285


Val Asp Tyr Val Asn Asp Arg Pro Thr Asn Asp Met Arg Tyr Pro Met 
    290                 295                 300


<210>  8360
<211>  1913
<212>  DNA
<213>  Homo sapiens

<400>  8360
agtagcaaga cgtgctaggc aatgaggagg gagatgagtt ttccgtaacc tgaagcaaca     60

tcctcctgat tcctcattaa agaaaaaggc gggaactagt caaaagccgg ggactgatgg    120

gacgctagga tctgcgcgtc ccgcccattt cggcctctga ctggtgaatg tcttcggctt    180

atggcagagg agcccgcctc attggctctc aggctccaga gcagcaggtc tccggcgccc    240

accccgcctc ccccagctgc cgacgtgggg cgggcagccg ccggcggctg ggagccgagg    300

cgtcggtgca gacctggaga cgggcatggg ggggctgcgg ctgctggctg tggccctcac    360

gtgctgctgg tggccgcagg gcagccaggg taagaccctg cggggcagct tcagcagcac    420

cgcggcccag gacgcccagg gccagcgcat cggccacttc gagttccatg gtgaccatgc    480

tcttctgtgt gtcagaatca acaacatagc agtagctgtt ggaaaagaag ctaaactcta    540

cctgttccaa gcccaggaat ggctaaagct acagcaaagc agtcatggtt atagctgtag    600

tgaaaaatta tccaaagctc agttgacaat gaccatgaac cagaccgaac ataatctgac    660

agtgtcccag attccgtctc cacaaacgtg gcatgtgttt tatgcagaca agtatacatg    720

ccaagatgac aaggagaatt ctcaggtgga agatatccca tttgaaatgg tgttactaaa    780

cccagatgcc gaagggaatc catttgatca ttttagtgct ggagaatctg ggttacatga    840

gttctttttc ctcctagtcc tagtgtactt tgtgattgct tgcatttatg ctcaatcatt    900

gtggcaggct attaagaaag gcggacccat gcacatgatt ttaaaggttc tgacaactgc    960

attgctgtta caagctggtt cagctttagc taattacatt catttctcca gttactccaa   1020

agatggaata ggggtaccat ttatgggaag tttggcagaa ttttttgaca tcgcttccca   1080

aattcagatg ttatacttac ttttgagtct atgcatgggt tggacaatag tcagaatgaa   1140

gaagtctcaa agcagacctc tccagtggga ttctacgcct gcatccactg gcattgcagt   1200

attcattgtc atgacacaga gtgttttgct actttgggaa cagtttgaag atatcagtca   1260

tcatagctac cattcacacc acaacttagc agggatcctc ctaattgttc taagaatttg   1320

cctagcattg tcattaggct gtggactcta tcagatcatc acagtggaga gaagtacact   1380

caaaagggag ttctacatca catttgccaa aggctgtatc ttgtggtttt tatgccatcc   1440

agttcttgca tgcatttctg tcatttttag cgactaccaa agagacaagg ttattacaat   1500

aggtgttatc ctttgccagt ctgtttccat ggttattctc tacagactct ttctgtctca   1560

cagtctatac tgggaagttt cttcactttc ttcagtaaca ctaccactga ccatatcatc   1620

tggacacaaa agtcgccctc atttctgata cttgattttt gttgagagga aaagtgaatt   1680

ggttaaaaga gtgcaataag gatccaaata cagtgacttt tttttcatac atttagtatg   1740

aaaacttgaa cagcgaaagc agagcatgtt atttatataa ctgcatttaa gcagtaccaa   1800

gactgaaaaa aaaggtaata aatgaaatgt tttgaaatat acttaaacaa caaactttga   1860

agaaagtgtt gttataaaat tattgaagcg atttctatgt ggaaataaat gtg          1913


<210>  8361
<211>  440
<212>  PRT
<213>  Homo sapiens

<400>  8361

Met Gly Gly Leu Arg Leu Leu Ala Val Ala Leu Thr Cys Cys Trp Trp 
1               5                   10                  15


Pro Gln Gly Ser Gln Gly Lys Thr Leu Arg Gly Ser Phe Ser Ser Thr 
            20                  25                  30


Ala Ala Gln Asp Ala Gln Gly Gln Arg Ile Gly His Phe Glu Phe His 
        35                  40                  45


Gly Asp His Ala Leu Leu Cys Val Arg Ile Asn Asn Ile Ala Val Ala 
    50                  55                  60


Val Gly Lys Glu Ala Lys Leu Tyr Leu Phe Gln Ala Gln Glu Trp Leu 
65                  70                  75                  80


Lys Leu Gln Gln Ser Ser His Gly Tyr Ser Cys Ser Glu Lys Leu Ser 
                85                  90                  95


Lys Ala Gln Leu Thr Met Thr Met Asn Gln Thr Glu His Asn Leu Thr 
            100                 105                 110


Val Ser Gln Ile Pro Ser Pro Gln Thr Trp His Val Phe Tyr Ala Asp 
        115                 120                 125


Lys Tyr Thr Cys Gln Asp Asp Lys Glu Asn Ser Gln Val Glu Asp Ile 
    130                 135                 140


Pro Phe Glu Met Val Leu Leu Asn Pro Asp Ala Glu Gly Asn Pro Phe 
145                 150                 155                 160


Asp His Phe Ser Ala Gly Glu Ser Gly Leu His Glu Phe Phe Phe Leu 
                165                 170                 175


Leu Val Leu Val Tyr Phe Val Ile Ala Cys Ile Tyr Ala Gln Ser Leu 
            180                 185                 190


Trp Gln Ala Ile Lys Lys Gly Gly Pro Met His Met Ile Leu Lys Val 
        195                 200                 205


Leu Thr Thr Ala Leu Leu Leu Gln Ala Gly Ser Ala Leu Ala Asn Tyr 
    210                 215                 220


Ile His Phe Ser Ser Tyr Ser Lys Asp Gly Ile Gly Val Pro Phe Met 
225                 230                 235                 240


Gly Ser Leu Ala Glu Phe Phe Asp Ile Ala Ser Gln Ile Gln Met Leu 
                245                 250                 255


Tyr Leu Leu Leu Ser Leu Cys Met Gly Trp Thr Ile Val Arg Met Lys 
            260                 265                 270


Lys Ser Gln Ser Arg Pro Leu Gln Trp Asp Ser Thr Pro Ala Ser Thr 
        275                 280                 285


Gly Ile Ala Val Phe Ile Val Met Thr Gln Ser Val Leu Leu Leu Trp 
    290                 295                 300


Glu Gln Phe Glu Asp Ile Ser His His Ser Tyr His Ser His His Asn 
305                 310                 315                 320


Leu Ala Gly Ile Leu Leu Ile Val Leu Arg Ile Cys Leu Ala Leu Ser 
                325                 330                 335


Leu Gly Cys Gly Leu Tyr Gln Ile Ile Thr Val Glu Arg Ser Thr Leu 
            340                 345                 350


Lys Arg Glu Phe Tyr Ile Thr Phe Ala Lys Gly Cys Ile Leu Trp Phe 
        355                 360                 365


Leu Cys His Pro Val Leu Ala Cys Ile Ser Val Ile Phe Ser Asp Tyr 
    370                 375                 380


Gln Arg Asp Lys Val Ile Thr Ile Gly Val Ile Leu Cys Gln Ser Val 
385                 390                 395                 400


Ser Met Val Ile Leu Tyr Arg Leu Phe Leu Ser His Ser Leu Tyr Trp 
                405                 410                 415


Glu Val Ser Ser Leu Ser Ser Val Thr Leu Pro Leu Thr Ile Ser Ser 
            420                 425                 430


Gly His Lys Ser Arg Pro His Phe 
        435                 440


<210>  8362
<211>  3578
<212>  DNA
<213>  Homo sapiens

<400>  8362
agtagcaaga cgtgctaggc aatgaggagg gagatgagtt ttccgtaacc tgaagcaaca     60

tcctcctgat tcctcattaa agaaaaaggc gggaactagt caaaagccgg ggactgatgg    120

gacgctagga tctgcgcgtc ccgcccattt cggcctctga ctggtgaatg tcttcggctt    180

atggcagagg agcccgcctc attggctctc aggctccaga gcagcaggtc tccggcgccc    240

accccgcctc ccccagctgc cgacgtgggg cgggcagccg ccggcggctg ggagccgagg    300

cgtcggtgca gacctggaga cgggcatggg ggggctgcgg ctgctggctg tggccctcac    360

gtgctgctgg tggccgcagg gcagccaggg taagaccctg cggggcagct tcagcagcac    420

cgcggcccag gacgcccagg gccagcgcat cggccacttc gagttccatg gtgaccatgc    480

tcttctgtgt gtcagaatca acaacatagc agtagctgtt ggaaaagaag ctaaactcta    540

cctgttccaa gcccaggaat ggctaaagct acagcaaagc agtcatggtt atagctgtag    600

tgaaaaatta tccaaagctc agttgacaat gaccatgaac cagaccgaac ataatctgac    660

agtgtcccag attccgtctc cacaaacgtg gcatgtgttt tatgcagaca agtatacatg    720

ccaagatgac aaggagaatt ctcaggtgga agatatccca tttgaaatgg tgttactaaa    780

cccagatgcc gaagggaatc catttgatca ttttagtgct ggagaatctg ttactccaaa    840

gatggaatag gggtaccatt tatgggaagt ttggcagaat tttttgacat cgcttcccaa    900

attcagatgt tatacttact tttgagtcta tgcatgggtt ggacaatagt cagaatgaag    960

aagtctcaaa gcagacctct ccagtgggat tctacgcctg catccactgg cattgcagta   1020

ttcattgtca tgacacagag tgttttgcta ctttgggaac agtttgaaga tatcagtcat   1080

catagctacc attcacacca caacttagca gggatcctcc taattgttct aagaatttgc   1140

ctagcattgt cattaggctg tggactctat cagatcatca cagtggagag aagtacactc   1200

aaaagggagt tctacatcac atttgccaaa ggctgtatct tgtggttttt atgccatcca   1260

gttcttgcat gcatttctgt catttttagc gactaccaaa gagacaaggt tattacaata   1320

ggtgttatcc tttgccagtc tgtttccatg gttattctct acagactctt tctgtctcac   1380

agtctatact gggaagtttc ttcactttct tcagtaacac taccactgac catatcatct   1440

ggacacaaaa gtcgccctca tttctgatac ttgatttttg ttgagaggaa aagtgaattg   1500

gttaaaagag tgcaataagg atccaaatac agtgactttt ttttcataca tttagtatga   1560

aaacttgaac agcgaaagca gagcatgtta tttatataac tgcatttaag cagtaccaag   1620

actgaaaaaa aaggtaataa atgaaatgtt ttgaaatata cttaaacaac aaactttgaa   1680

gaaagtgttg ttataaaatt attgaagcga tttctatgtg gaaataaatg tgaaaaataa   1740

ctatgatatt ttggtaaaat attcaccact tataatgcct catcttaata gctaactcag   1800

gtttaatagt cttataaaaa gtaatcagtt aaatgattac ttgcttataa atatctaaac   1860

tagtccagtt atgaaatcag tgtaatacat tgatttttaa aactgctgct ttttatgctt   1920

taaggaaaat gtatttcata tttgagttta aaggaattga aattacttca ggaaatgaat   1980

ataaaatagg ttcacagtta aatgaataag cttttgttta tttgtgggtg gagttattct   2040

ccaatttttt ctgccatttt tggctctagt tcaggtttta gcttgattag caaaggtttt   2100

tgacaaacag tttatgaaaa aataaaactt aaatacatta cacgggttgt aaggacaaag   2160

gattttaaaa tctgagcact taggtgaagg gacaagcagg tttatgtgtt taaacagaaa   2220

gaagggaaaa ggtactatgt gatatggtac tgaaattttg atcccaatag aattcatttc   2280

tcttacgttg aatccccaat cataattaag ccgtatacac agattaaatt aacagaagca   2340

tttcacataa atgttggttt cagtcatcaa ctacccatga attcctgccc aaggatactt   2400

aatcaggatt aaattttcta tgaataattg aaaaacaaaa cactcactgg atttgttata   2460

atccgtgttg gcactggatt ctaagtagtt gccatcttga atcctttgta ataaagccat   2520

acttttgtgt gtgtgtgtga tgccccagta ttgagtatgc tagctaaaaa atatcaagtg   2580

cctgattaaa gaattgctaa atggttgtca atactcgctg tataaaatga gtattcccat   2640

taatagtcac tgattggaaa ttattctgtt gctgtttgtc aagctgttca ggccttttcc   2700

tttttacttc tggcttattt taaaaatatt ttttatctat ttactgtgtg tttaagcaag   2760

caacagtgca ctgatctggt agttaaattt tttaattaaa tagttaaaat aatgtagtgc   2820

aacttaaaaa tatctatggc tttgtttttg tttttctttt gtacctagtc tcattggaaa   2880

tgactagtat tctgcctcat tttcagggca gaatatgtgt ttgtgaccca aaatgacaaa   2940

gttaccaagt tcaacctgct cattaaatca tctctctatt agttctttgt aaatcactta   3000

gtacattaga gctacaggtt aagactagaa agtctgagtt atgttttagg tatacatgat   3060

cgtctgagtg gtcataacct tttcttttat catgtctcgc taataacccc agctattgtc   3120

tgttgtgttc agctgagatg caaaaaagaa attaagcaaa aaagaaaaag atgaagactt   3180

ttcatgaatt ttgtgaactt gccaaaaggg gaagggaaaa atctttgtgt tacttcactc   3240

aaagaacata agtaactgca attaacatat atgaaattta ttactctgct tgcatttatg   3300

aaactaacca gttttttaaa ctttaattct taaatttatg gttggaaatg ctgataattt   3360

attttgttat ttaagagctg ttgttaagtg gaggaaagta gttgttaata aatgtataaa   3420

actgttcttg actagtaatc agggacaaaa tttatagttc ataagtcatg acacagtatt   3480

cgctcttttt ctgaatgttt acatagagat tcatcactgc agattacaga aagttaagtg   3540

tatactacaa actctaatta aagataaaaa tcttttct                           3578


<210>  8363
<211>  201
<212>  PRT
<213>  Homo sapiens

<400>  8363

Met Gly Ser Leu Ala Glu Phe Phe Asp Ile Ala Ser Gln Ile Gln Met 
1               5                   10                  15


Leu Tyr Leu Leu Leu Ser Leu Cys Met Gly Trp Thr Ile Val Arg Met 
            20                  25                  30


Lys Lys Ser Gln Ser Arg Pro Leu Gln Trp Asp Ser Thr Pro Ala Ser 
        35                  40                  45


Thr Gly Ile Ala Val Phe Ile Val Met Thr Gln Ser Val Leu Leu Leu 
    50                  55                  60


Trp Glu Gln Phe Glu Asp Ile Ser His His Ser Tyr His Ser His His 
65                  70                  75                  80


Asn Leu Ala Gly Ile Leu Leu Ile Val Leu Arg Ile Cys Leu Ala Leu 
                85                  90                  95


Ser Leu Gly Cys Gly Leu Tyr Gln Ile Ile Thr Val Glu Arg Ser Thr 
            100                 105                 110


Leu Lys Arg Glu Phe Tyr Ile Thr Phe Ala Lys Gly Cys Ile Leu Trp 
        115                 120                 125


Phe Leu Cys His Pro Val Leu Ala Cys Ile Ser Val Ile Phe Ser Asp 
    130                 135                 140


Tyr Gln Arg Asp Lys Val Ile Thr Ile Gly Val Ile Leu Cys Gln Ser 
145                 150                 155                 160


Val Ser Met Val Ile Leu Tyr Arg Leu Phe Leu Ser His Ser Leu Tyr 
                165                 170                 175


Trp Glu Val Ser Ser Leu Ser Ser Val Thr Leu Pro Leu Thr Ile Ser 
            180                 185                 190


Ser Gly His Lys Ser Arg Pro His Phe 
        195                 200


<210>  8364
<211>  4921
<212>  DNA
<213>  Homo sapiens

<400>  8364
agtagcaaga cgtgctaggc aatgaggagg gagatgagtt ttccgtaacc tgaagcaaca     60

tcctcctgat tcctcattaa agaaaaaggc gggaactagt caaaagccgg ggactgatgg    120

gacgctagga tctgcgcgtc ccgcccattt cggcctctga ctggtgaatg tcttcggctt    180

atggcagagg agcccgcctc attggctctc aggctccaga gcagcaggtc tccggcgccc    240

accccgcctc ccccagctgc cgacgtgggg cgggcagccg ccggcggctg ggagccgagg    300

cgtcggtgca gacctggaga cgggcatggg ggggctgcgg ctgctggctg tggccctcac    360

gtgctgctgg tggccgcagg gcagccaggg taagaccctg cggggcagct tcagcagcac    420

cgcggcccag gacgcccagg gccagcgcat cggccacttc gagttccatg gtgaccatgc    480

tcttctgtgt gtcagaatca acaacatagc agtagctgtt ggaaaagaag ctaaactcta    540

cctgttccaa gcccaggaat ggctaaagct acagcaaagc agtcatggtt atagctgtag    600

tgaaaaatta tccaaagctc agttgacaat gaccatgaac cagaccgaac ataatctgac    660

agtgtcccag attccgtctc cacaaacgtg gcatgtgttt tatgcagaca agtatacatg    720

ccaagatgac aaggagaatt ctcaggtgga agatatccca tttgaaatgg tgttactaaa    780

cccagatgcc gaagggaatc catttgatca ttttagtgct ggagaatctg ggttacatga    840

gttctttttc ctcctagtcc tagtgtactt tgtgattgct tgcatttatg ctcaatcatt    900

gtggcaggct attaagaaag gcggacccat gcacatgatt ttaaaggttc tgacaactgc    960

attgctgtta caagctggtt cagctttagc taattacatt catttctcca gttactccaa   1020

agatggaata ggggtaccat ttatgggaag tttggcagaa ttttttgaca tcgcttccca   1080

aattcagatg ttatacttac ttttgagtct atgcatgggt tggacaatag tcagaatgaa   1140

gaagtctcaa agcagacctc tccagtggga ttctacgcct gcatccactg gcattgcagt   1200

attcattgtc atgacacaga gtgttttgct actttgggaa cagtttgaag atatcagtca   1260

tcatagctac cattcacacc acaacttagc agggatcctc ctaattgttc taagaatttg   1320

cctagcattg tcattaggct gtggactcta tcagatcatc acagtggaga gaagtacact   1380

caaaagggag ttctacatca catttgccaa aggctgtatc ttgtggtttt tatgccatcc   1440

agttcttgca tgcatttctg tcatttttag cgactaccaa agagacaagg ttattacaat   1500

aggtgttatc ctttgccagt ctgtttccat ggttattctc tacagactct ttctgtctca   1560

cagtctatac tgggaagttt cttcactttc ttcagtaaca ctaccactga ccatatcatc   1620

tggacacaaa agtcgccctc atttctgata cttgattttt gttgagagga aaagtgaatt   1680

ggttaaaaga gtgcaataag gatccaaata cagtgacttt tttttcatac atttagtatg   1740

aaaacttgaa cagcgaaagc agagcatgtt atttatataa ctgcatttaa gcagtaccaa   1800

gactgaaaaa aaaggtaata aatgaaatgt tttgaaatat acttaaacaa caaactttga   1860

agaaagtgtt gttataaaat tattgaagcg atttctatgt ggaaataaat gtgaaaaata   1920

actatgatat tttggtaaaa tattcaccac ttataatgcc tcatcttaat agctaactca   1980

ggtttaatag tcttataaaa agtaatcagt taaatgatta cttgcttata aatatctaaa   2040

ctagtccagt tatgaaatca gtgtaataca ttgattttta aaactgctgc tttttatgct   2100

ttaaggaaaa tgtatttcat atttgagttt aaaggaattg aaattacttc aggaaatgaa   2160

tataaaatag gttcacagtt aaatgaataa gcttttgttt atttgtgggt ggagttattc   2220

tccaattttt tctgccattt ttggctctag ttcaggtttt agcttgatta gcaaaggttt   2280

ttgacaaaca gtttatgaaa aaataaaact taaatacatt acacgggttg taaggacaaa   2340

ggattttaaa atctgagcac ttaggtgaag ggacaagcag gtttatgtgt ttaaacagaa   2400

agaagggaaa aggtactatg tgatatggta ctgaaatttt gatcccaata gaattcattt   2460

ctcttacgtt gaatccccaa tcataattaa gccgtataca cagattaaat taacagaagc   2520

atttcacata aatgttggtt tcagtcatca actacccatg aattcctgcc caaggatact   2580

taatcaggat taaattttct atgaataatt gaaaaacaaa acactcactg gatttgttat   2640

aatccgtgtt ggcactggat tctaagtagt tgccatcttg aatcctttgt aataaagcca   2700

tacttttgtg tgtgtgtgtg atgccccagt attgagtatg ctagctaaaa aatatcaagt   2760

gcctgattaa agaattgcta aatggttgtc aatactcgct gtataaaatg agtattccca   2820

ttaatagtca ctgattggaa attattctgt tgctgtttgt caagctgttc aggccttttc   2880

ctttttactt ctggcttatt ttaaaaatat tttttatcta tttactgtgt gtttaagcaa   2940

gcaacagtgc actgatctgg tagttaaatt ttttaattaa atagttaaaa taatgtagtg   3000

caacttaaaa atatctatgg ctttgttttt gtttttcttt tgtacctagt ctcattggaa   3060

atgactagta ttctgcctca ttttcagggc agaatatgtg tttgtgaccc aaaatgacaa   3120

agttaccaag ttcaacctgc tcattaaatc atctctctat tagttctttg taaatcactt   3180

agtacattag agctacaggt taagactaga aagtctgagt tatgttttag gtatacatga   3240

tcgtctgagt ggtcataacc ttttctttta tcatgtctcg ctaataaccc cagctattgt   3300

ctgttgtgtt cagctgagat gcaaaaaaga aattaagcaa aaaagaaaaa gatgaagact   3360

tttcatgaat tttgtgaact tgccaaaagg ggaagggaaa aatctttgtg ttacttcact   3420

caaagaacat aagtaactgc aattaacata tatgaaattt attactctgc ttgcatttat   3480

gaaactaacc agttttttaa actttaattc ttaaatttat ggttggaaat gctgataatt   3540

tattttgtta tttaagagct gttgttaagt ggaggaaagt agttgttaat aaatgtataa   3600

aactgttctt gactagtaat cagggacaaa atttatagtt cataagtcat gacacagtat   3660

tcgctctttt tctgaatgtt tacatagaga ttcatcactg cagattacag aaagttaagt   3720

gtatactaca aactctaatt aaagataaaa atcttttcta cttttctttg tcagataatg   3780

cttttttatg tgtttttaca ttttttgaaa gaagataaat ggttcatcca gagctttatt   3840

aagaagcatt tcttttcttc ccttaaaaaa tagatgctta tttttattga catgtgtata   3900

ataagatggg tgcctactgt gatgcatttt accaggcatt ttaccttcat tattactcat   3960

ctctattgtg ataaccaggc tcccatttaa ctgagtataa gagagaataa atgatttctc   4020

taaggtcatc aaactattta gtttttccac tttaccttca tgatttaagg aacatgtatt   4080

agctgtgttt tagtgagaat gaattgctat ccatcataat ttttgctgtt gatttgaaca   4140

ttaaaactgg aattgtgcta aaatcagaac atgcgcttga atatctgtaa gacctcagca   4200

cacttcagta tttgaacctg gcttttaacc agacagtatt actagcagga gagttaatct   4260

aggcagaaga gcttgcttta gggtaattat ttattatctc cagtaaagtc acatctgatg   4320

aacataggag atacacaaat ctgagatcat ctctaaaata atgagactag aacctatcta   4380

tcaacatgaa catgggctcc ttcagcatgt ttcttctagg agactgcacg ttctttggaa   4440

tttggaaatt tggaattatc tgtgaaacat tttcttaaat agcttctgtg gtatcaaatc   4500

attgaggttg ttttttgttt gttttgagaa ttgatatgat tgttagaagt agccagatac   4560

gaagaggtaa tactgttttt tattccaaca tgtatttgtg aattgagact aaaataatga   4620

gattggtttt cctctgtgat ctgaaagtag tgtggtagaa gcaccgtagc ttgatttctt   4680

gcaatagctc tctaagtaat attaccatgt ccacacttgg gcagccttct gcacagctcc   4740

aggggcatca tatgtgttgt gctgtaggag tgccatgaag cctggaggtg aggaaagaag   4800

tgatcctgcc cactagggcc attctccaca gtgtagccaa aacaatctct taaaaatgga   4860

aatcatctgg atgatgagca tacagaaatt ctttgtgcta atcttgtaat ttttttgtaa   4920

g                                                                   4921


<210>  8365
<211>  440
<212>  PRT
<213>  Homo sapiens

<400>  8365

Met Gly Gly Leu Arg Leu Leu Ala Val Ala Leu Thr Cys Cys Trp Trp 
1               5                   10                  15


Pro Gln Gly Ser Gln Gly Lys Thr Leu Arg Gly Ser Phe Ser Ser Thr 
            20                  25                  30


Ala Ala Gln Asp Ala Gln Gly Gln Arg Ile Gly His Phe Glu Phe His 
        35                  40                  45


Gly Asp His Ala Leu Leu Cys Val Arg Ile Asn Asn Ile Ala Val Ala 
    50                  55                  60


Val Gly Lys Glu Ala Lys Leu Tyr Leu Phe Gln Ala Gln Glu Trp Leu 
65                  70                  75                  80


Lys Leu Gln Gln Ser Ser His Gly Tyr Ser Cys Ser Glu Lys Leu Ser 
                85                  90                  95


Lys Ala Gln Leu Thr Met Thr Met Asn Gln Thr Glu His Asn Leu Thr 
            100                 105                 110


Val Ser Gln Ile Pro Ser Pro Gln Thr Trp His Val Phe Tyr Ala Asp 
        115                 120                 125


Lys Tyr Thr Cys Gln Asp Asp Lys Glu Asn Ser Gln Val Glu Asp Ile 
    130                 135                 140


Pro Phe Glu Met Val Leu Leu Asn Pro Asp Ala Glu Gly Asn Pro Phe 
145                 150                 155                 160


Asp His Phe Ser Ala Gly Glu Ser Gly Leu His Glu Phe Phe Phe Leu 
                165                 170                 175


Leu Val Leu Val Tyr Phe Val Ile Ala Cys Ile Tyr Ala Gln Ser Leu 
            180                 185                 190


Trp Gln Ala Ile Lys Lys Gly Gly Pro Met His Met Ile Leu Lys Val 
        195                 200                 205


Leu Thr Thr Ala Leu Leu Leu Gln Ala Gly Ser Ala Leu Ala Asn Tyr 
    210                 215                 220


Ile His Phe Ser Ser Tyr Ser Lys Asp Gly Ile Gly Val Pro Phe Met 
225                 230                 235                 240


Gly Ser Leu Ala Glu Phe Phe Asp Ile Ala Ser Gln Ile Gln Met Leu 
                245                 250                 255


Tyr Leu Leu Leu Ser Leu Cys Met Gly Trp Thr Ile Val Arg Met Lys 
            260                 265                 270


Lys Ser Gln Ser Arg Pro Leu Gln Trp Asp Ser Thr Pro Ala Ser Thr 
        275                 280                 285


Gly Ile Ala Val Phe Ile Val Met Thr Gln Ser Val Leu Leu Leu Trp 
    290                 295                 300


Glu Gln Phe Glu Asp Ile Ser His His Ser Tyr His Ser His His Asn 
305                 310                 315                 320


Leu Ala Gly Ile Leu Leu Ile Val Leu Arg Ile Cys Leu Ala Leu Ser 
                325                 330                 335


Leu Gly Cys Gly Leu Tyr Gln Ile Ile Thr Val Glu Arg Ser Thr Leu 
            340                 345                 350


Lys Arg Glu Phe Tyr Ile Thr Phe Ala Lys Gly Cys Ile Leu Trp Phe 
        355                 360                 365


Leu Cys His Pro Val Leu Ala Cys Ile Ser Val Ile Phe Ser Asp Tyr 
    370                 375                 380


Gln Arg Asp Lys Val Ile Thr Ile Gly Val Ile Leu Cys Gln Ser Val 
385                 390                 395                 400


Ser Met Val Ile Leu Tyr Arg Leu Phe Leu Ser His Ser Leu Tyr Trp 
                405                 410                 415


Glu Val Ser Ser Leu Ser Ser Val Thr Leu Pro Leu Thr Ile Ser Ser 
            420                 425                 430


Gly His Lys Ser Arg Pro His Phe 
        435                 440


<210>  8366
<211>  2659
<212>  DNA
<213>  Homo sapiens

<400>  8366
attgtggcag gctattaaga aaggcggacc catgcacatg attttaaagg ttctgacaac     60

tgcattgctg ttacaagctg gttcagcttt agctaattac attcatttct ccaggtaact    120

caaaaccact aaaactgtgt tcatcattac atctaattaa tcctaattag tccaccaaaa    180

ttatgcttgc tttgattata aacaattttt ttcacatttg taatttacac tactcttctt    240

caattcctca gttactccaa agatggaata ggggtaccat ttatgggaag tttggcagaa    300

tgtgagtatc tttctgagca ttttttaaaa agcttttaca ctcgctatct gctttttttt    360

tatttcttgt catagtataa attttctgtc gaaaattgtt tagaaatcag cttgactgag    420

aacaggatta cagtttaagt tcccatatgt cttacttagt ttcttcttaa taataggtaa    480

tgtgtacagc tcctcgttgt ttttttgttt gtttgtttga gacagggttc ttactccgta    540

gcccaggctg gagtgcagtg gcacagtcac ggctcactgc agcctcaaac tcctaggctc    600

aggtgatcct cctgcctcag gccttcccag tagctgggat tacaggcaca taccatcatg    660

cctggctgat ttttaaattt ccttttctgt agatggggtc tcactatgtt gcccaggctg    720

gccttatact cttgggcttg agggatccac ccaccctggc ctcccaaagt cctggaatta    780

caggcatgag tctccacact ctgccttttc attgttttta ggtatattta tatacattct    840

ctcatcttat cctcaataga aaaggggtct gcatatcctt attttgcaga taaaggatct    900

gggctcagtg atgtgaaaca tacttccaca tgtcagtcag ctattgagtg gtagagacta    960

gactcagacc taaattttct tacctcaaag ctgaagtttt tcttcctatt ataattccac   1020

tctctgttat aactgactct tttctatttc tgacccaaag cctaaaactc acatcaaaat   1080

atgctgtgaa gaaaagtgat aagttttctt aaaaatcatt aaatgctacc tcataaaata   1140

aatatatata tgaaacttga agcatttata gatttctgtt gttttcttgt agtgttaacc   1200

tggatacagg tggttttgat acatcttttc tgtttgaagt agcaggcttc ccctgcagtg   1260

taggtgatgg ccacctggtg gcacatcaca ctaatgcatg gagcttctca tttgtcttca   1320

ggattctgaa agtaaagcca atgtttggat gttatgggag ctatgcattt cattgtattg   1380

tttcttgtta atagttttag aaaatactct tcacattata gttcagccat caaaaaaaat   1440

tcacccagaa atgaaggtac tagtattctc catattgcag aaatcgtatt tagaatttgc   1500

tttaataagc agtgagttat agagaacagg attatgtagt tagaaaagct aagaaaaatg   1560

ggaaacgaaa agagttaagg ttggacttaa tggacatatg gtatgggcat atatatgtat   1620

ttttaaatag tattgctgct gttttaacta ttttaataaa tatattacaa aatttatggc   1680

aatttttaaa tctttagaat tattacctgc gaatatctct taatgaattt cgttagcttc   1740

tctttgaaaa tggctttttg tggtttttct taaaaaaaaa aaaagatgtt ctcaatgcaa   1800

aaagcactaa attttttata ttgtgaaaac ttggttgacg ttggttttca tgtcccatta   1860

gtttttgaca tcgcttccca aattcagatg ttatacttac ttttgagtct atgcatgggt   1920

tggacaatag tcagaatgaa gaagtctcaa agcagacctc tccagtggga ttctacgcct   1980

gcatccactg gcattgcagt attcattgtc atgacacaga gtgttttgct actttgggaa   2040

cagtttgaag atatcagtca tcatagctac cattcacacc acaacttagc agggatcctc   2100

ctaattgttc taagaatttg cctagcattg tcattaggct gtggactcta tcagatcatc   2160

acagtggaga gaagtacact caaaagggag ttctacatca catttgccaa aggctgtatc   2220

ttgtggtttt tatgccatcc agttcttgca tgcatttctg tcatttttag cgactaccaa   2280

agagacaagg ttattacaat aggtgttatc ctttgccagt ctgtttccat ggttattctc   2340

tacagactct ttctgtctca cagtctatac tgggaagttt cttcactttc ttcagtaaca   2400

ctaccactga ccatatcatc tggacacaaa agtcgccctc atttctgata cttgattttt   2460

gttgagagga aaagtgaatt ggttaaaaga gtgcaataag gatccaaata cagtgacttt   2520

tttttcatac atttagtatg aaaacttgaa cagcgaaagc agagcatgtt atttatataa   2580

ctgcatttaa gcagtaccaa gactgaaaaa aaaggtaata aatgaaatgt tttgaaatat   2640

acttaaacaa caaactttg                                                2659


<210>  8367
<211>  220
<212>  PRT
<213>  Homo sapiens

<400>  8367

Met Phe Ser Met Gln Lys Ala Leu Asn Phe Leu Tyr Cys Glu Asn Leu 
1               5                   10                  15


Val Asp Val Gly Phe His Val Pro Leu Val Phe Asp Ile Ala Ser Gln 
            20                  25                  30


Ile Gln Met Leu Tyr Leu Leu Leu Ser Leu Cys Met Gly Trp Thr Ile 
        35                  40                  45


Val Arg Met Lys Lys Ser Gln Ser Arg Pro Leu Gln Trp Asp Ser Thr 
    50                  55                  60


Pro Ala Ser Thr Gly Ile Ala Val Phe Ile Val Met Thr Gln Ser Val 
65                  70                  75                  80


Leu Leu Leu Trp Glu Gln Phe Glu Asp Ile Ser His His Ser Tyr His 
                85                  90                  95


Ser His His Asn Leu Ala Gly Ile Leu Leu Ile Val Leu Arg Ile Cys 
            100                 105                 110


Leu Ala Leu Ser Leu Gly Cys Gly Leu Tyr Gln Ile Ile Thr Val Glu 
        115                 120                 125


Arg Ser Thr Leu Lys Arg Glu Phe Tyr Ile Thr Phe Ala Lys Gly Cys 
    130                 135                 140


Ile Leu Trp Phe Leu Cys His Pro Val Leu Ala Cys Ile Ser Val Ile 
145                 150                 155                 160


Phe Ser Asp Tyr Gln Arg Asp Lys Val Ile Thr Ile Gly Val Ile Leu 
                165                 170                 175


Cys Gln Ser Val Ser Met Val Ile Leu Tyr Arg Leu Phe Leu Ser His 
            180                 185                 190


Ser Leu Tyr Trp Glu Val Ser Ser Leu Ser Ser Val Thr Leu Pro Leu 
        195                 200                 205


Thr Ile Ser Ser Gly His Lys Ser Arg Pro His Phe 
    210                 215                 220


<210>  8368
<211>  593
<212>  DNA
<213>  Homo sapiens

<400>  8368
aaacacaggg gaattctgca caacaaacat ttgcgcgagc gctctccctc gccccctctc     60

gcttagctgg atttttgtaa gggggtttct tttaaattgg attatccgaa tggtcgccca    120

tatggcctta ctctgcctgc atagactggc cgggtgaaga cgagtgaaag gacgcacgga    180

gagcctgaga cagaagatag agaacttctt cagagcagcg taggaaaagt gggtgctggg    240

tgaaacggaa ggcaaagaga gagaatagaa gaagaatcta caagaacgag aatgcaacag    300

cagcattgca gacgcacctt caggttcacc tgcggaaggc acgcccaggg cggaggagtg    360

gcgggactgg cggaagatca ggaggcggcg gaggacccca gggttcccaa cactgacccc    420

tccgcaaagt tcctccctgg gagaagagac tggccagctc ttgttctaag ggaagcaagc    480

tgctccatgg aaagacccac agggcaagag ctgatgtatc tggccaaagg acagcaaaga    540

cttgaggcct gtcagcagct aagtgaaaaa gtcacccgat caaaccttga gat           593


<210>  8369
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  8369

Met Gln Gln Gln His Cys Arg Arg Thr Phe Arg Phe Thr Cys Gly Arg 
1               5                   10                  15


His Ala Gln Gly Gly Gly Val Ala Gly Leu Ala Glu Asp Gln Glu Ala 
            20                  25                  30


Ala Glu Asp Pro Arg Val Pro Asn Thr Asp Pro Ser Ala Lys Phe Leu 
        35                  40                  45


Pro Gly Arg Arg Asp Trp Pro Ala Leu Val Leu Arg Glu Ala Ser Cys 
    50                  55                  60


Ser Met Glu Arg Pro Thr Gly Gln Glu Leu Met Tyr Leu Ala Lys Gly 
65                  70                  75                  80


Gln Gln Arg Leu Glu Ala Cys Gln Gln Leu Ser Glu Lys Val Thr Arg 
                85                  90                  95


Ser Asn Leu 



<210>  8370
<211>  5843
<212>  DNA
<213>  Homo sapiens

<400>  8370
gagcggacag gcgtggcggc cggagcccca gcatccctgc ttgaggtcca ggagcggagc     60

ccgcggccac cgccgcctga tcagcgcgac cccggcccgc gcccgccccg cccggcaaga    120

tgctgcccgt gtaccaggag gtgaagccca acccgctgca ggacgcgaac ctctgctcac    180

gcgtgttctt ctggtggctc aatcccttgt ttaaaattgg ccataaacgg agattagagg    240

aagatgatat gtattcagtg ctgccagaag accgctcaca gcaccttgga gaggagttgc    300

aagggttctg ggataaagaa gttttaagag ctgagaatga cgcacagaag ccttctttaa    360

caagagcaat cataaagtgt tactggaaat cttatttagt tttgggaatt tttacgttaa    420

ttgaggaaag tgccaaagta atccagccca tatttttggg aaaaattatt aattattttg    480

aaaattatga tcccatggat tctgtggctt tgaacacagc gtacgcctat gccacggtgc    540

tgactttttg cacgctcatt ttggctatac tgcatcactt atatttttat cacgttcagt    600

gtgctgggat gaggttacga gtagccatgt gccatatgat ttatcggaag gcacttcgtc    660

ttagtaacat ggccatgggg aagacaacca caggccagat agtcaatctg ctgtccaatg    720

atgtgaacaa gtttgatcag gtgacagtgt tcttacactt cctgtgggca ggaccactgc    780

aggcgattgc agtgactgcc ctactctgga tggagatagg aatatcgtgc cttgctggga    840

tggcagttct aatcattctc ctgcccttgc aaagctgttt tgggaagttg ttctcatcac    900

tgaggagtaa aactgcaact ttcacggatg ccaggatcag gaccatgaat gaagttataa    960

ctggtataag gataataaaa atgtacgcct gggaaaagtc attttcaaat cttattacca   1020

atttgagaaa gaaggagatt tccaagattc tgagaagttc ctgcctcaga gggatgaatt   1080

tggcttcatt tttcagtgca agcaaaatca tcgtgtttgt gaccttcacc acctacgtgc   1140

tcctcggcag tgtgatcaca gccagccgcg tgttcgtggc agtgacgctg tatggggctg   1200

tgcggctgac ggttaccctc ttcttcccct cagccattga gagggtgtca gaggcaatcg   1260

tcagcatccg aagaatccag acctttttgc tacttgatga gatatcacag cgcaaccgtc   1320

agctgccgtc agatggtaaa aagatggtgc atgtgcagga ttttactgct ttttgggata   1380

aggcatcaga gaccccaact ctacaaggcc tttcctttac tgtcagacct ggcgaattgt   1440

tagctgtggt cggccccgtg ggagcaggga agtcatcact gttaagtgcc gtgctcgggg   1500

aattggcccc aagtcacggg ctggtcagcg tgcatggaag aattgcctat gtgtctcagc   1560

agccctgggt gttctcggga actctgagga gtaatatttt atttgggaag aaatacgaaa   1620

aggaacgata tgaaaaagtc ataaaggctt gtgctctgaa aaaggattta cagctgttgg   1680

aggatggtga tctgactgtg ataggagatc ggggaaccac gctgagtgga gggcagaaag   1740

cacgggtaaa ccttgcaaga gcagtgtatc aagatgctga catctatctc ctggacgatc   1800

ctctcagtgc agtagatgcg gaagttagca gacacttgtt cgaactgtgt atttgtcaaa   1860

ttttgcatga gaagatcaca attttagtga ctcatcagtt gcagtacctc aaagctgcaa   1920

gtcagattct gatattgaaa gatggtaaaa tggtgcagaa ggggacttac actgagttcc   1980

taaaatctgg tatagatttt ggctcccttt taaagaagga taatgaggaa agtgaacaac   2040

ctccagttcc aggaactccc acactaagga atcgtacctt ctcagagtct tcggtttggt   2100

ctcaacaatc ttctagaccc tccttgaaag atggtgctct ggagagccaa gatacagaga   2160

atgtcccagt tacactatca gaggagaacc gttctgaagg aaaagttggt tttcaggcct   2220

ataagaatta cttcagagct ggtgctcact ggattgtctt cattttcctt attctcctaa   2280

acactgcagc tcaggttgcc tatgtgcttc aagattggtg gctttcatac tgggcaaaca   2340

aacaaagtat gctaaatgtc actgtaaatg gaggaggaaa tgtaaccgag aagctagatc   2400

ttaactggta cttaggaatt tattcaggtt taactgtagc taccgttctt tttggcatag   2460

caagatctct attggtattc tacgtccttg ttaactcttc acaaactttg cacaacaaaa   2520

tgtttgagtc aattctgaaa gctccggtat tattctttga tagaaatcca ataggaagaa   2580

ttttaaatcg tttctccaaa gacattggac acttggatga tttgctgccg ctgacgtttt   2640

tagatttcat ccagacattg ctacaagtgg ttggtgtggt ctctgtggct gtggccgtga   2700

ttccttggat cgcaataccc ttggttcccc ttggaatcat tttcattttt cttcggcgat   2760

attttttgga aacgtcaaga gatgtgaagc gcctggaatc tacaactcgg agtccagtgt   2820

tttcccactt atcatcttct ctccaggggc tctggaccat ccgggcatac aaagcagaag   2880

agaggtgtca ggaactgttt gatgcacacc aggatttaca ttcagaggct tggttcttgt   2940

ttttgacaac gtcccgctgg tttgccgtcc gtctggatgc catctgtgcc atgtttgtca   3000

tcatcgttgc ctttgggtcc ctgattctgg caaaaactct ggatgccggg caggttggtt   3060

tggcactgtc ctatgccctc acgctcatgg ggatgtttca gtggtgtgtt cgacaaagtg   3120

ctgaagttga gaatatgatg atctcagtag aaagggtcat tgaatacaca gaccttgaaa   3180

aagaagcacc ttgggaatat cagaaacgcc caccaccagc ctggccccat gaaggagtga   3240

taatctttga caatgtgaac ttcatgtaca gtccaggtgg gcctctggta ctgaagcatc   3300

tgacagcact cattaaatca caagaaaagg ttggcattgt gggaagaacc ggagctggaa   3360

aaagttccct catctcagcc ctttttagat tgtcagaacc cgaaggtaaa atttggattg   3420

ataagatctt gacaactgaa attggacttc acgatttaag gaagaagatg tcaatcatac   3480

ctcaggaacc tgttttgttc actggaacaa tgaggaaaaa cctggatccc tttaatgagc   3540

acacggatga ggaactgtgg aatgccttac aagaggtaca acttaaagaa accattgaag   3600

atcttcctgg taaaatggat actgaattag cagaatcagg atccaatttt agtgttggac   3660

aaagacaact ggtgtgcctt gccagggcaa ttctcaggaa aaatcagata ttgattattg   3720

atgaagcgac ggcaaatgtg gatccaagaa ctgatgagtt aatacaaaaa aaaatccggg   3780

agaaatttgc ccactgcacc gtgctaacca ttgcacacag attgaacacc attattgaca   3840

gcgacaagat aatggtttta gattcaggaa gactgaaaga atatgatgag ccgtatgttt   3900

tgctgcaaaa taaagagagc ctattttaca agatggtgca acaactgggc aaggcagaag   3960

ccgctgccct cactgaaaca gcaaaacagg tatacttcaa aagaaattat ccacatattg   4020

gtcacactga ccacatggtt acaaacactt ccaatggaca gccctcgacc ttaactattt   4080

tcgagacagc actgtgaatc caaccaaaat gtcaagtccg ttccgaaggc attttccact   4140

agtttttgga ctatgtaaac cacattgtac ttttttttac tttggcaaca aatatttata   4200

catacaagat gctagttcat ttgaatattt ctcccaactt atccaaggat ctccagctct   4260

aacaaaatgg tttattttta tttaaatgtc aatagttgtt ttttaaaatc caaatcagag   4320

gtgcaggcca ccagttaaat gccgtctatc aggttttgtg ccttaagaga ctacagagtc   4380

aaagctcatt tttaaaggag taggacaaag ttgtcacagg tttttgttgt tgtttttatt   4440

gcccccaaaa ttacatgtta atttccattt atatcaggga ttctatttac ttgaagactg   4500

tgaagttgcc attttgtctc attgttttct ttgacataac taggatccat tatttcccct   4560

gaaggcttct tgttagaaaa tagtacagtt acaaccaata ggaacaacaa aaagaaaaag   4620

tttgtgacat tgtagtaggg agtgtgtacc ccttactccc catcaaaaaa aaaaatggat   4680

acatggttaa aggatagaag ggcaatattt tatcatatgt tctaaaagag aaggaagaga   4740

aaatactact ttctcaaaat ggaagccctt aaaggtgctt tgatactgaa ggacacaaat   4800

gtgaccgtcc atcctccttt agagttgcat gacttggaca cggtaactgt tgcagtttta   4860

gactcagcat tgtgacactt cccaagaagg ccaaacctct aaccgacatt cctgaaatac   4920

gtggcattat tcttttttgg atttctcatt tatggaaggc taaccctctg ttgactgtaa   4980

gccttttggt ttgggctgta ttgaaatcct ttctaaattg catgaatagg ctctgctaac   5040

gtgatgagac aaactgaaaa ttattgcaag cattgactat aattatgcag tacgttctca   5100

ggatgcatcc aggggttcat tttcatgagc ctgtccaggt tagtttactc ctgaccacta   5160

atagcattgt catttgggct ttctgttgaa tgaatcaaca aaccacaata cttcctggga   5220

ccttttgtac tttatttgaa ctatgagtct ttaatttttc ctgatgatgg tggctgtaat   5280

atgttgagtt cagtttacta aaggttttac tattatggtt tgaagtggag tctcatgacc   5340

tctcagaata aggtgtcacc tccctgaaat tgcatatatg tatatagaca tgcacacgtg   5400

tgcatttgtt tgtatacata tatttgtcct tcgtatagca agttttttgc tcatcagcag   5460

agagcaacag atgttttatt gagtgaagcc ttaaaaagca cacaccacac acagctaact   5520

gccaaaatac attgaccgta gtagctgttc aactcctagt acttagaaat acacgtatgg   5580

ttaatgttca gtccaacaaa ccacacacag taaatgttta ttaatagtca tggttcgtat   5640

tttaggtgac tgaaattgca tcagtgatca taatgaggtt tgttaaaacg atagctatat   5700

tcaaaatgtc tatatgttta tttggacttt tgaggttaaa gacagtcata taaacgtcct   5760

gtttctgttt taatgttatc atagaatttt ttaatgaaac taaattcaat tgaaataaat   5820

gatagttttc atctccattc aga                                           5843


<210>  8371
<211>  1325
<212>  PRT
<213>  Homo sapiens

<400>  8371

Met Leu Pro Val Tyr Gln Glu Val Lys Pro Asn Pro Leu Gln Asp Ala 
1               5                   10                  15


Asn Leu Cys Ser Arg Val Phe Phe Trp Trp Leu Asn Pro Leu Phe Lys 
            20                  25                  30


Ile Gly His Lys Arg Arg Leu Glu Glu Asp Asp Met Tyr Ser Val Leu 
        35                  40                  45


Pro Glu Asp Arg Ser Gln His Leu Gly Glu Glu Leu Gln Gly Phe Trp 
    50                  55                  60


Asp Lys Glu Val Leu Arg Ala Glu Asn Asp Ala Gln Lys Pro Ser Leu 
65                  70                  75                  80


Thr Arg Ala Ile Ile Lys Cys Tyr Trp Lys Ser Tyr Leu Val Leu Gly 
                85                  90                  95


Ile Phe Thr Leu Ile Glu Glu Ser Ala Lys Val Ile Gln Pro Ile Phe 
            100                 105                 110


Leu Gly Lys Ile Ile Asn Tyr Phe Glu Asn Tyr Asp Pro Met Asp Ser 
        115                 120                 125


Val Ala Leu Asn Thr Ala Tyr Ala Tyr Ala Thr Val Leu Thr Phe Cys 
    130                 135                 140


Thr Leu Ile Leu Ala Ile Leu His His Leu Tyr Phe Tyr His Val Gln 
145                 150                 155                 160


Cys Ala Gly Met Arg Leu Arg Val Ala Met Cys His Met Ile Tyr Arg 
                165                 170                 175


Lys Ala Leu Arg Leu Ser Asn Met Ala Met Gly Lys Thr Thr Thr Gly 
            180                 185                 190


Gln Ile Val Asn Leu Leu Ser Asn Asp Val Asn Lys Phe Asp Gln Val 
        195                 200                 205


Thr Val Phe Leu His Phe Leu Trp Ala Gly Pro Leu Gln Ala Ile Ala 
    210                 215                 220


Val Thr Ala Leu Leu Trp Met Glu Ile Gly Ile Ser Cys Leu Ala Gly 
225                 230                 235                 240


Met Ala Val Leu Ile Ile Leu Leu Pro Leu Gln Ser Cys Phe Gly Lys 
                245                 250                 255


Leu Phe Ser Ser Leu Arg Ser Lys Thr Ala Thr Phe Thr Asp Ala Arg 
            260                 265                 270


Ile Arg Thr Met Asn Glu Val Ile Thr Gly Ile Arg Ile Ile Lys Met 
        275                 280                 285


Tyr Ala Trp Glu Lys Ser Phe Ser Asn Leu Ile Thr Asn Leu Arg Lys 
    290                 295                 300


Lys Glu Ile Ser Lys Ile Leu Arg Ser Ser Cys Leu Arg Gly Met Asn 
305                 310                 315                 320


Leu Ala Ser Phe Phe Ser Ala Ser Lys Ile Ile Val Phe Val Thr Phe 
                325                 330                 335


Thr Thr Tyr Val Leu Leu Gly Ser Val Ile Thr Ala Ser Arg Val Phe 
            340                 345                 350


Val Ala Val Thr Leu Tyr Gly Ala Val Arg Leu Thr Val Thr Leu Phe 
        355                 360                 365


Phe Pro Ser Ala Ile Glu Arg Val Ser Glu Ala Ile Val Ser Ile Arg 
    370                 375                 380


Arg Ile Gln Thr Phe Leu Leu Leu Asp Glu Ile Ser Gln Arg Asn Arg 
385                 390                 395                 400


Gln Leu Pro Ser Asp Gly Lys Lys Met Val His Val Gln Asp Phe Thr 
                405                 410                 415


Ala Phe Trp Asp Lys Ala Ser Glu Thr Pro Thr Leu Gln Gly Leu Ser 
            420                 425                 430


Phe Thr Val Arg Pro Gly Glu Leu Leu Ala Val Val Gly Pro Val Gly 
        435                 440                 445


Ala Gly Lys Ser Ser Leu Leu Ser Ala Val Leu Gly Glu Leu Ala Pro 
    450                 455                 460


Ser His Gly Leu Val Ser Val His Gly Arg Ile Ala Tyr Val Ser Gln 
465                 470                 475                 480


Gln Pro Trp Val Phe Ser Gly Thr Leu Arg Ser Asn Ile Leu Phe Gly 
                485                 490                 495


Lys Lys Tyr Glu Lys Glu Arg Tyr Glu Lys Val Ile Lys Ala Cys Ala 
            500                 505                 510


Leu Lys Lys Asp Leu Gln Leu Leu Glu Asp Gly Asp Leu Thr Val Ile 
        515                 520                 525


Gly Asp Arg Gly Thr Thr Leu Ser Gly Gly Gln Lys Ala Arg Val Asn 
    530                 535                 540


Leu Ala Arg Ala Val Tyr Gln Asp Ala Asp Ile Tyr Leu Leu Asp Asp 
545                 550                 555                 560


Pro Leu Ser Ala Val Asp Ala Glu Val Ser Arg His Leu Phe Glu Leu 
                565                 570                 575


Cys Ile Cys Gln Ile Leu His Glu Lys Ile Thr Ile Leu Val Thr His 
            580                 585                 590


Gln Leu Gln Tyr Leu Lys Ala Ala Ser Gln Ile Leu Ile Leu Lys Asp 
        595                 600                 605


Gly Lys Met Val Gln Lys Gly Thr Tyr Thr Glu Phe Leu Lys Ser Gly 
    610                 615                 620


Ile Asp Phe Gly Ser Leu Leu Lys Lys Asp Asn Glu Glu Ser Glu Gln 
625                 630                 635                 640


Pro Pro Val Pro Gly Thr Pro Thr Leu Arg Asn Arg Thr Phe Ser Glu 
                645                 650                 655


Ser Ser Val Trp Ser Gln Gln Ser Ser Arg Pro Ser Leu Lys Asp Gly 
            660                 665                 670


Ala Leu Glu Ser Gln Asp Thr Glu Asn Val Pro Val Thr Leu Ser Glu 
        675                 680                 685


Glu Asn Arg Ser Glu Gly Lys Val Gly Phe Gln Ala Tyr Lys Asn Tyr 
    690                 695                 700


Phe Arg Ala Gly Ala His Trp Ile Val Phe Ile Phe Leu Ile Leu Leu 
705                 710                 715                 720


Asn Thr Ala Ala Gln Val Ala Tyr Val Leu Gln Asp Trp Trp Leu Ser 
                725                 730                 735


Tyr Trp Ala Asn Lys Gln Ser Met Leu Asn Val Thr Val Asn Gly Gly 
            740                 745                 750


Gly Asn Val Thr Glu Lys Leu Asp Leu Asn Trp Tyr Leu Gly Ile Tyr 
        755                 760                 765


Ser Gly Leu Thr Val Ala Thr Val Leu Phe Gly Ile Ala Arg Ser Leu 
    770                 775                 780


Leu Val Phe Tyr Val Leu Val Asn Ser Ser Gln Thr Leu His Asn Lys 
785                 790                 795                 800


Met Phe Glu Ser Ile Leu Lys Ala Pro Val Leu Phe Phe Asp Arg Asn 
                805                 810                 815


Pro Ile Gly Arg Ile Leu Asn Arg Phe Ser Lys Asp Ile Gly His Leu 
            820                 825                 830


Asp Asp Leu Leu Pro Leu Thr Phe Leu Asp Phe Ile Gln Thr Leu Leu 
        835                 840                 845


Gln Val Val Gly Val Val Ser Val Ala Val Ala Val Ile Pro Trp Ile 
    850                 855                 860


Ala Ile Pro Leu Val Pro Leu Gly Ile Ile Phe Ile Phe Leu Arg Arg 
865                 870                 875                 880


Tyr Phe Leu Glu Thr Ser Arg Asp Val Lys Arg Leu Glu Ser Thr Thr 
                885                 890                 895


Arg Ser Pro Val Phe Ser His Leu Ser Ser Ser Leu Gln Gly Leu Trp 
            900                 905                 910


Thr Ile Arg Ala Tyr Lys Ala Glu Glu Arg Cys Gln Glu Leu Phe Asp 
        915                 920                 925


Ala His Gln Asp Leu His Ser Glu Ala Trp Phe Leu Phe Leu Thr Thr 
    930                 935                 940


Ser Arg Trp Phe Ala Val Arg Leu Asp Ala Ile Cys Ala Met Phe Val 
945                 950                 955                 960


Ile Ile Val Ala Phe Gly Ser Leu Ile Leu Ala Lys Thr Leu Asp Ala 
                965                 970                 975


Gly Gln Val Gly Leu Ala Leu Ser Tyr Ala Leu Thr Leu Met Gly Met 
            980                 985                 990


Phe Gln Trp Cys Val Arg Gln Ser Ala Glu Val Glu Asn Met Met Ile 
        995                 1000                1005


Ser Val Glu Arg Val Ile Glu Tyr Thr Asp Leu Glu Lys Glu Ala Pro 
    1010                1015                1020


Trp Glu Tyr Gln Lys Arg Pro Pro Pro Ala Trp Pro His Glu Gly Val 
1025                1030                1035                1040


Ile Ile Phe Asp Asn Val Asn Phe Met Tyr Ser Pro Gly Gly Pro Leu 
                1045                1050                1055


Val Leu Lys His Leu Thr Ala Leu Ile Lys Ser Gln Glu Lys Val Gly 
            1060                1065                1070


Ile Val Gly Arg Thr Gly Ala Gly Lys Ser Ser Leu Ile Ser Ala Leu 
        1075                1080                1085


Phe Arg Leu Ser Glu Pro Glu Gly Lys Ile Trp Ile Asp Lys Ile Leu 
    1090                1095                1100


Thr Thr Glu Ile Gly Leu His Asp Leu Arg Lys Lys Met Ser Ile Ile 
1105                1110                1115                1120


Pro Gln Glu Pro Val Leu Phe Thr Gly Thr Met Arg Lys Asn Leu Asp 
                1125                1130                1135


Pro Phe Asn Glu His Thr Asp Glu Glu Leu Trp Asn Ala Leu Gln Glu 
            1140                1145                1150


Val Gln Leu Lys Glu Thr Ile Glu Asp Leu Pro Gly Lys Met Asp Thr 
        1155                1160                1165


Glu Leu Ala Glu Ser Gly Ser Asn Phe Ser Val Gly Gln Arg Gln Leu 
    1170                1175                1180


Val Cys Leu Ala Arg Ala Ile Leu Arg Lys Asn Gln Ile Leu Ile Ile 
1185                1190                1195                1200


Asp Glu Ala Thr Ala Asn Val Asp Pro Arg Thr Asp Glu Leu Ile Gln 
                1205                1210                1215


Lys Lys Ile Arg Glu Lys Phe Ala His Cys Thr Val Leu Thr Ile Ala 
            1220                1225                1230


His Arg Leu Asn Thr Ile Ile Asp Ser Asp Lys Ile Met Val Leu Asp 
        1235                1240                1245


Ser Gly Arg Leu Lys Glu Tyr Asp Glu Pro Tyr Val Leu Leu Gln Asn 
    1250                1255                1260


Lys Glu Ser Leu Phe Tyr Lys Met Val Gln Gln Leu Gly Lys Ala Glu 
1265                1270                1275                1280


Ala Ala Ala Leu Thr Glu Thr Ala Lys Gln Val Tyr Phe Lys Arg Asn 
                1285                1290                1295


Tyr Pro His Ile Gly His Thr Asp His Met Val Thr Asn Thr Ser Asn 
            1300                1305                1310


Gly Gln Pro Ser Thr Leu Thr Ile Phe Glu Thr Ala Leu 
        1315                1320                1325


<210>  8372
<211>  5702
<212>  DNA
<213>  Homo sapiens

<400>  8372
gagcggacag gcgtggcggc cggagcccca gcatccctgc ttgaggtcca ggagcggagc     60

ccgcggccac cgccgcctga tcagcgcgac cccggcccgc gcccgccccg cccggcaaga    120

tgctgcccgt gtaccaggag gtgaagccca acccgctgca ggacgcgaac ctctgctcac    180

gcgtgttctt ctggtggctc aatcccttgt ttaaaattgg ccataaacgg agattagagg    240

aagatgatat gtattcagtg ctgccagaag accgctcaca gcaccttgga gaggagttgc    300

aagggttctg ggataaagaa gttttaagag ctgagaatga cgcacagaag ccttctttaa    360

caagagcaat cataaagtgt tactggaaat cttatttagt tttgggaatt tttacgttaa    420

ttgaggaaag tgccaaagta atccagccca tatttttggg aaaaattatt aattattttg    480

aaaattatga tcccatggat tctgtggctt tgaacacagc gtacgcctat gccacggtgc    540

tgactttttg cacgctcatt ttggctatac tgcatcactt atatttttat cacgttcagt    600

gtgctgggat gaggttacga gtagccatgt gccatatgat ttatcggaag gcacttcgtc    660

ttagtaacat ggccatgggg aagacaacca caggccagat agtcaatctg ctgtccaatg    720

atgtgaacaa gtttgatcag gtgacagtgt tcttacactt cctgtgggca ggaccactgc    780

aggcgattgc agtgactgcc ctactctgga tggagatagg aatatcgtgc cttgctggga    840

tggcagttct aatcattctc ctgcccttgc aaagctgttt tgggaagttg ttctcatcac    900

tgaggagtaa aactgcaact ttcacggatg ccaggatcag gaccatgaat gaagttataa    960

ctggtataag gataataaaa atgtacgcct gggaaaagtc attttcaaat cttattacca   1020

atttgagaaa gaaggagatt tccaagattc tgagaagttc ctgcctcaga gggatgaatt   1080

tggcttcatt tttcagtgca agcaaaatca tcgtgtttgt gaccttcacc acctacgtgc   1140

tcctcggcag tgtgatcaca gccagccgcg tgttcgtggc agtgacgctg tatggggctg   1200

tgcggctgac ggttaccctc ttcttcccct cagccattga gagggtgtca gaggcaatcg   1260

tcagcatccg aagaatccag acctttttgc tacttgatga gatatcacag cgcaaccgtc   1320

agctgccgtc agatggtaaa aagatggtgc atgtgcagga ttttactgct ttttgggata   1380

aggcatcaga gaccccaact ctacaaggcc tttcctttac tgtcagacct ggcgaattgt   1440

tagctgtggt cggccccgtg ggagcaggga agtcatcact gttaagtgcc gtgctcgggg   1500

aattggcccc aagtcacggg ctggtcagcg tgcatggaag aattgcctat gtgtctcagc   1560

agccctgggt gttctcggga actctgagga gtaatatttt atttgggaag aaatacgaaa   1620

aggaacgata tgaaaaagtc ataaaggctt gtgctctgaa aaaggattta cagctgttgg   1680

aggatggtga tctgactgtg ataggagatc ggggaaccac gctgagtgga gggcagaaag   1740

cacgggtaaa ccttgcaaga gcagtgtatc aagatgctga catctatctc ctggacgatc   1800

ctctcagtgc agtagatgcg gaagttagca gacacttgtt cgaactgtgt atttgtcaaa   1860

ttttgcatga gaagatcaca attttagtga ctcatcagtt gcagtacctc aaagctgcaa   1920

gtcagattct gatattgaaa gatggtaaaa tggtgcagaa ggggacttac actgagttcc   1980

taaaatctgg tatagatttt ggctcccttt taaagaagga taatgaggaa agtgaacaac   2040

ctccagttcc aggaactccc acactaagga atcgtacctt ctcagagtct tcggtttggt   2100

ctcaacaatc ttctagaccc tccttgaaag atggtgctct ggagagccaa gatgttgcct   2160

atgtgcttca agattggtgg ctttcatact gggcaaacaa acaaagtatg ctaaatgtca   2220

ctgtaaatgg aggaggaaat gtaaccgaga agctagatct taactggtac ttaggaattt   2280

attcaggttt aactgtagct accgttcttt ttggcatagc aagatctcta ttggtattct   2340

acgtccttgt taactcttca caaactttgc acaacaaaat gtttgagtca attctgaaag   2400

ctccggtatt attctttgat agaaatccaa taggaagaat tttaaatcgt ttctccaaag   2460

acattggaca cttggatgat ttgctgccgc tgacgttttt agatttcatc cagacattgc   2520

tacaagtggt tggtgtggtc tctgtggctg tggccgtgat tccttggatc gcaataccct   2580

tggttcccct tggaatcatt ttcatttttc ttcggcgata ttttttggaa acgtcaagag   2640

atgtgaagcg cctggaatct acaactcgga gtccagtgtt ttcccactta tcatcttctc   2700

tccaggggct ctggaccatc cgggcataca aagcagaaga gaggtgtcag gaactgtttg   2760

atgcacacca ggatttacat tcagaggctt ggttcttgtt tttgacaacg tcccgctggt   2820

ttgccgtccg tctggatgcc atctgtgcca tgtttgtcat catcgttgcc tttgggtccc   2880

tgattctggc aaaaactctg gatgccgggc aggttggttt ggcactgtcc tatgccctca   2940

cgctcatggg gatgtttcag tggtgtgttc gacaaagtgc tgaagttgag aatatgatga   3000

tctcagtaga aagggtcatt gaatacacag accttgaaaa agaagcacct tgggaatatc   3060

agaaacgccc accaccagcc tggccccatg aaggagtgat aatctttgac aatgtgaact   3120

tcatgtacag tccaggtggg cctctggtac tgaagcatct gacagcactc attaaatcac   3180

aagaaaaggt tggcattgtg ggaagaaccg gagctggaaa aagttccctc atctcagccc   3240

tttttagatt gtcagaaccc gaaggtaaaa tttggattga taagatcttg acaactgaaa   3300

ttggacttca cgatttaagg aagaagatgt caatcatacc tcaggaacct gttttgttca   3360

ctggaacaat gaggaaaaac ctggatccct ttaatgagca cacggatgag gaactgtgga   3420

atgccttaca agaggtacaa cttaaagaaa ccattgaaga tcttcctggt aaaatggata   3480

ctgaattagc agaatcagga tccaatttta gtgttggaca aagacaactg gtgtgccttg   3540

ccagggcaat tctcaggaaa aatcagatat tgattattga tgaagcgacg gcaaatgtgg   3600

atccaagaac tgatgagtta atacaaaaaa aaatccggga gaaatttgcc cactgcaccg   3660

tgctaaccat tgcacacaga ttgaacacca ttattgacag cgacaagata atggttttag   3720

attcaggaag actgaaagaa tatgatgagc cgtatgtttt gctgcaaaat aaagagagcc   3780

tattttacaa gatggtgcaa caactgggca aggcagaagc cgctgccctc actgaaacag   3840

caaaacaggt atacttcaaa agaaattatc cacatattgg tcacactgac cacatggtta   3900

caaacacttc caatggacag ccctcgacct taactatttt cgagacagca ctgtgaatcc   3960

aaccaaaatg tcaagtccgt tccgaaggca ttttccacta gtttttggac tatgtaaacc   4020

acattgtact tttttttact ttggcaacaa atatttatac atacaagatg ctagttcatt   4080

tgaatatttc tcccaactta tccaaggatc tccagctcta acaaaatggt ttatttttat   4140

ttaaatgtca atagttgttt tttaaaatcc aaatcagagg tgcaggccac cagttaaatg   4200

ccgtctatca ggttttgtgc cttaagagac tacagagtca aagctcattt ttaaaggagt   4260

aggacaaagt tgtcacaggt ttttgttgtt gtttttattg cccccaaaat tacatgttaa   4320

tttccattta tatcagggat tctatttact tgaagactgt gaagttgcca ttttgtctca   4380

ttgttttctt tgacataact aggatccatt atttcccctg aaggcttctt gttagaaaat   4440

agtacagtta caaccaatag gaacaacaaa aagaaaaagt ttgtgacatt gtagtaggga   4500

gtgtgtaccc cttactcccc atcaaaaaaa aaaatggata catggttaaa ggatagaagg   4560

gcaatatttt atcatatgtt ctaaaagaga aggaagagaa aatactactt tctcaaaatg   4620

gaagccctta aaggtgcttt gatactgaag gacacaaatg tgaccgtcca tcctccttta   4680

gagttgcatg acttggacac ggtaactgtt gcagttttag actcagcatt gtgacacttc   4740

ccaagaaggc caaacctcta accgacattc ctgaaatacg tggcattatt cttttttgga   4800

tttctcattt atggaaggct aaccctctgt tgactgtaag ccttttggtt tgggctgtat   4860

tgaaatcctt tctaaattgc atgaataggc tctgctaacg tgatgagaca aactgaaaat   4920

tattgcaagc attgactata attatgcagt acgttctcag gatgcatcca ggggttcatt   4980

ttcatgagcc tgtccaggtt agtttactcc tgaccactaa tagcattgtc atttgggctt   5040

tctgttgaat gaatcaacaa accacaatac ttcctgggac cttttgtact ttatttgaac   5100

tatgagtctt taatttttcc tgatgatggt ggctgtaata tgttgagttc agtttactaa   5160

aggttttact attatggttt gaagtggagt ctcatgacct ctcagaataa ggtgtcacct   5220

ccctgaaatt gcatatatgt atatagacat gcacacgtgt gcatttgttt gtatacatat   5280

atttgtcctt cgtatagcaa gttttttgct catcagcaga gagcaacaga tgttttattg   5340

agtgaagcct taaaaagcac acaccacaca cagctaactg ccaaaataca ttgaccgtag   5400

tagctgttca actcctagta cttagaaata cacgtatggt taatgttcag tccaacaaac   5460

cacacacagt aaatgtttat taatagtcat ggttcgtatt ttaggtgact gaaattgcat   5520

cagtgatcat aatgaggttt gttaaaacga tagctatatt caaaatgtct atatgtttat   5580

ttggactttt gaggttaaag acagtcatat aaacgtcctg tttctgtttt aatgttatca   5640

tagaattttt taatgaaact aaattcaatt gaaataaatg atagttttca tctccattca   5700

ga                                                                  5702


<210>  8373
<211>  1278
<212>  PRT
<213>  Homo sapiens

<400>  8373

Met Leu Pro Val Tyr Gln Glu Val Lys Pro Asn Pro Leu Gln Asp Ala 
1               5                   10                  15


Asn Leu Cys Ser Arg Val Phe Phe Trp Trp Leu Asn Pro Leu Phe Lys 
            20                  25                  30


Ile Gly His Lys Arg Arg Leu Glu Glu Asp Asp Met Tyr Ser Val Leu 
        35                  40                  45


Pro Glu Asp Arg Ser Gln His Leu Gly Glu Glu Leu Gln Gly Phe Trp 
    50                  55                  60


Asp Lys Glu Val Leu Arg Ala Glu Asn Asp Ala Gln Lys Pro Ser Leu 
65                  70                  75                  80


Thr Arg Ala Ile Ile Lys Cys Tyr Trp Lys Ser Tyr Leu Val Leu Gly 
                85                  90                  95


Ile Phe Thr Leu Ile Glu Glu Ser Ala Lys Val Ile Gln Pro Ile Phe 
            100                 105                 110


Leu Gly Lys Ile Ile Asn Tyr Phe Glu Asn Tyr Asp Pro Met Asp Ser 
        115                 120                 125


Val Ala Leu Asn Thr Ala Tyr Ala Tyr Ala Thr Val Leu Thr Phe Cys 
    130                 135                 140


Thr Leu Ile Leu Ala Ile Leu His His Leu Tyr Phe Tyr His Val Gln 
145                 150                 155                 160


Cys Ala Gly Met Arg Leu Arg Val Ala Met Cys His Met Ile Tyr Arg 
                165                 170                 175


Lys Ala Leu Arg Leu Ser Asn Met Ala Met Gly Lys Thr Thr Thr Gly 
            180                 185                 190


Gln Ile Val Asn Leu Leu Ser Asn Asp Val Asn Lys Phe Asp Gln Val 
        195                 200                 205


Thr Val Phe Leu His Phe Leu Trp Ala Gly Pro Leu Gln Ala Ile Ala 
    210                 215                 220


Val Thr Ala Leu Leu Trp Met Glu Ile Gly Ile Ser Cys Leu Ala Gly 
225                 230                 235                 240


Met Ala Val Leu Ile Ile Leu Leu Pro Leu Gln Ser Cys Phe Gly Lys 
                245                 250                 255


Leu Phe Ser Ser Leu Arg Ser Lys Thr Ala Thr Phe Thr Asp Ala Arg 
            260                 265                 270


Ile Arg Thr Met Asn Glu Val Ile Thr Gly Ile Arg Ile Ile Lys Met 
        275                 280                 285


Tyr Ala Trp Glu Lys Ser Phe Ser Asn Leu Ile Thr Asn Leu Arg Lys 
    290                 295                 300


Lys Glu Ile Ser Lys Ile Leu Arg Ser Ser Cys Leu Arg Gly Met Asn 
305                 310                 315                 320


Leu Ala Ser Phe Phe Ser Ala Ser Lys Ile Ile Val Phe Val Thr Phe 
                325                 330                 335


Thr Thr Tyr Val Leu Leu Gly Ser Val Ile Thr Ala Ser Arg Val Phe 
            340                 345                 350


Val Ala Val Thr Leu Tyr Gly Ala Val Arg Leu Thr Val Thr Leu Phe 
        355                 360                 365


Phe Pro Ser Ala Ile Glu Arg Val Ser Glu Ala Ile Val Ser Ile Arg 
    370                 375                 380


Arg Ile Gln Thr Phe Leu Leu Leu Asp Glu Ile Ser Gln Arg Asn Arg 
385                 390                 395                 400


Gln Leu Pro Ser Asp Gly Lys Lys Met Val His Val Gln Asp Phe Thr 
                405                 410                 415


Ala Phe Trp Asp Lys Ala Ser Glu Thr Pro Thr Leu Gln Gly Leu Ser 
            420                 425                 430


Phe Thr Val Arg Pro Gly Glu Leu Leu Ala Val Val Gly Pro Val Gly 
        435                 440                 445


Ala Gly Lys Ser Ser Leu Leu Ser Ala Val Leu Gly Glu Leu Ala Pro 
    450                 455                 460


Ser His Gly Leu Val Ser Val His Gly Arg Ile Ala Tyr Val Ser Gln 
465                 470                 475                 480


Gln Pro Trp Val Phe Ser Gly Thr Leu Arg Ser Asn Ile Leu Phe Gly 
                485                 490                 495


Lys Lys Tyr Glu Lys Glu Arg Tyr Glu Lys Val Ile Lys Ala Cys Ala 
            500                 505                 510


Leu Lys Lys Asp Leu Gln Leu Leu Glu Asp Gly Asp Leu Thr Val Ile 
        515                 520                 525


Gly Asp Arg Gly Thr Thr Leu Ser Gly Gly Gln Lys Ala Arg Val Asn 
    530                 535                 540


Leu Ala Arg Ala Val Tyr Gln Asp Ala Asp Ile Tyr Leu Leu Asp Asp 
545                 550                 555                 560


Pro Leu Ser Ala Val Asp Ala Glu Val Ser Arg His Leu Phe Glu Leu 
                565                 570                 575


Cys Ile Cys Gln Ile Leu His Glu Lys Ile Thr Ile Leu Val Thr His 
            580                 585                 590


Gln Leu Gln Tyr Leu Lys Ala Ala Ser Gln Ile Leu Ile Leu Lys Asp 
        595                 600                 605


Gly Lys Met Val Gln Lys Gly Thr Tyr Thr Glu Phe Leu Lys Ser Gly 
    610                 615                 620


Ile Asp Phe Gly Ser Leu Leu Lys Lys Asp Asn Glu Glu Ser Glu Gln 
625                 630                 635                 640


Pro Pro Val Pro Gly Thr Pro Thr Leu Arg Asn Arg Thr Phe Ser Glu 
                645                 650                 655


Ser Ser Val Trp Ser Gln Gln Ser Ser Arg Pro Ser Leu Lys Asp Gly 
            660                 665                 670


Ala Leu Glu Ser Gln Asp Val Ala Tyr Val Leu Gln Asp Trp Trp Leu 
        675                 680                 685


Ser Tyr Trp Ala Asn Lys Gln Ser Met Leu Asn Val Thr Val Asn Gly 
    690                 695                 700


Gly Gly Asn Val Thr Glu Lys Leu Asp Leu Asn Trp Tyr Leu Gly Ile 
705                 710                 715                 720


Tyr Ser Gly Leu Thr Val Ala Thr Val Leu Phe Gly Ile Ala Arg Ser 
                725                 730                 735


Leu Leu Val Phe Tyr Val Leu Val Asn Ser Ser Gln Thr Leu His Asn 
            740                 745                 750


Lys Met Phe Glu Ser Ile Leu Lys Ala Pro Val Leu Phe Phe Asp Arg 
        755                 760                 765


Asn Pro Ile Gly Arg Ile Leu Asn Arg Phe Ser Lys Asp Ile Gly His 
    770                 775                 780


Leu Asp Asp Leu Leu Pro Leu Thr Phe Leu Asp Phe Ile Gln Thr Leu 
785                 790                 795                 800


Leu Gln Val Val Gly Val Val Ser Val Ala Val Ala Val Ile Pro Trp 
                805                 810                 815


Ile Ala Ile Pro Leu Val Pro Leu Gly Ile Ile Phe Ile Phe Leu Arg 
            820                 825                 830


Arg Tyr Phe Leu Glu Thr Ser Arg Asp Val Lys Arg Leu Glu Ser Thr 
        835                 840                 845


Thr Arg Ser Pro Val Phe Ser His Leu Ser Ser Ser Leu Gln Gly Leu 
    850                 855                 860


Trp Thr Ile Arg Ala Tyr Lys Ala Glu Glu Arg Cys Gln Glu Leu Phe 
865                 870                 875                 880


Asp Ala His Gln Asp Leu His Ser Glu Ala Trp Phe Leu Phe Leu Thr 
                885                 890                 895


Thr Ser Arg Trp Phe Ala Val Arg Leu Asp Ala Ile Cys Ala Met Phe 
            900                 905                 910


Val Ile Ile Val Ala Phe Gly Ser Leu Ile Leu Ala Lys Thr Leu Asp 
        915                 920                 925


Ala Gly Gln Val Gly Leu Ala Leu Ser Tyr Ala Leu Thr Leu Met Gly 
    930                 935                 940


Met Phe Gln Trp Cys Val Arg Gln Ser Ala Glu Val Glu Asn Met Met 
945                 950                 955                 960


Ile Ser Val Glu Arg Val Ile Glu Tyr Thr Asp Leu Glu Lys Glu Ala 
                965                 970                 975


Pro Trp Glu Tyr Gln Lys Arg Pro Pro Pro Ala Trp Pro His Glu Gly 
            980                 985                 990


Val Ile Ile Phe Asp Asn Val Asn Phe Met Tyr Ser Pro Gly Gly Pro 
        995                 1000                1005


Leu Val Leu Lys His Leu Thr Ala Leu Ile Lys Ser Gln Glu Lys Val 
    1010                1015                1020


Gly Ile Val Gly Arg Thr Gly Ala Gly Lys Ser Ser Leu Ile Ser Ala 
1025                1030                1035                1040


Leu Phe Arg Leu Ser Glu Pro Glu Gly Lys Ile Trp Ile Asp Lys Ile 
                1045                1050                1055


Leu Thr Thr Glu Ile Gly Leu His Asp Leu Arg Lys Lys Met Ser Ile 
            1060                1065                1070


Ile Pro Gln Glu Pro Val Leu Phe Thr Gly Thr Met Arg Lys Asn Leu 
        1075                1080                1085


Asp Pro Phe Asn Glu His Thr Asp Glu Glu Leu Trp Asn Ala Leu Gln 
    1090                1095                1100


Glu Val Gln Leu Lys Glu Thr Ile Glu Asp Leu Pro Gly Lys Met Asp 
1105                1110                1115                1120


Thr Glu Leu Ala Glu Ser Gly Ser Asn Phe Ser Val Gly Gln Arg Gln 
                1125                1130                1135


Leu Val Cys Leu Ala Arg Ala Ile Leu Arg Lys Asn Gln Ile Leu Ile 
            1140                1145                1150


Ile Asp Glu Ala Thr Ala Asn Val Asp Pro Arg Thr Asp Glu Leu Ile 
        1155                1160                1165


Gln Lys Lys Ile Arg Glu Lys Phe Ala His Cys Thr Val Leu Thr Ile 
    1170                1175                1180


Ala His Arg Leu Asn Thr Ile Ile Asp Ser Asp Lys Ile Met Val Leu 
1185                1190                1195                1200


Asp Ser Gly Arg Leu Lys Glu Tyr Asp Glu Pro Tyr Val Leu Leu Gln 
                1205                1210                1215


Asn Lys Glu Ser Leu Phe Tyr Lys Met Val Gln Gln Leu Gly Lys Ala 
            1220                1225                1230


Glu Ala Ala Ala Leu Thr Glu Thr Ala Lys Gln Val Tyr Phe Lys Arg 
        1235                1240                1245


Asn Tyr Pro His Ile Gly His Thr Asp His Met Val Thr Asn Thr Ser 
    1250                1255                1260


Asn Gly Gln Pro Ser Thr Leu Thr Ile Phe Glu Thr Ala Leu 
1265                1270                1275


<210>  8374
<211>  870
<212>  DNA
<213>  Homo sapiens

<400>  8374
cagacattgc tacaagtggt tggtgtggtc tctgtggctg tggccgtgat tccttggatc     60

gcaataccct tggttcccct tggaatcatt ttcatttttc ttcggcgata ttttttggaa    120

acgtcaagag atgtgaagcg cctggaatct acaactcgga gtccagtgtt ttcccactta    180

tcatcttctc tccaggggct ctggaccatc cgggcataca aagcagaaga gaggtgtcag    240

gaactgtttg atgcacacca ggatttacat tcaggtctgt ctatttctgg aaatggtttc    300

aaaggacagg atctgctgct ttttctggct taacctccct ggtcagatga gcttgttggc    360

aggcacctca gggcccagcc ccacatcctg ctttttttgc gcatcttcgt ctccttcccc    420

atccccttct tctgggcttg gactcctctc ggaatcgctg ctgcacgttc cctctttgtg    480

ccccctgact ggcttgtggg gtctttctct caccatgcat ggcctgtggc tctgtcagca    540

aacgttttct gcaaaaggcc acctagtaag tgttttaggc attgtgtgcc attattgtct    600

ctgttgtgat gaatcacctt tgccattgta gcacaaaagc agatgtcaat acattggcaa    660

atggctgtga ctatgtttca ataaaacttt atttacaaaa ataggtgctg gctcacgtgc    720

tgtagtttgc tgaccccttg catcagtgaa gattttttca atatggaaat ttcagaattt    780

ccaccaaatc tacaaaattc agatccgtca ttccaatctt tattttatct tgctgattaa    840

atggcacttt aaaaaccaca tgctaaaagg                                     870


<210>  8375
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  8375

Met His Thr Arg Ile Tyr Ile Gln Val Cys Leu Phe Leu Glu Met Val 
1               5                   10                  15


Ser Lys Asp Arg Ile Cys Cys Phe Phe Trp Leu Asn Leu Pro Gly Gln 
            20                  25                  30


Met Ser Leu Leu Ala Gly Thr Ser Gly Pro Ser Pro Thr Ser Cys Phe 
        35                  40                  45


Phe Cys Ala Ser Ser Ser Pro Ser Pro Ser Pro Ser Ser Gly Leu Gly 
    50                  55                  60


Leu Leu Ser Glu Ser Leu Leu His Val Pro Ser Leu Cys Pro Leu Thr 
65                  70                  75                  80


Gly Leu Trp Gly Leu Ser Leu Thr Met His Gly Leu Trp Leu Cys Gln 
                85                  90                  95


Gln Thr Phe Ser Ala Lys Gly His Leu Val Ser Val Leu Gly Ile Val 
            100                 105                 110


Cys His Tyr Cys Leu Cys Cys Asp Glu Ser Pro Leu Pro Leu 
        115                 120                 125


<210>  8376
<211>  2889
<212>  DNA
<213>  Homo sapiens

<400>  8376
gagcggacag gcgtggcggc cggagcccca gcatccctgc ttgaggtcca ggagcggagc     60

ccgcggccac cgccgcctga tcagcgcgac cccggcccgc gcccgccccg cccggcaaga    120

tgctgcccgt gtaccaggag gtgaagccca acccgctgca ggacgcgaac ctctgctcac    180

gcgtgttctt ctggtggctc aatcccttgt ttaaaattgg ccataaacgg agattagagg    240

aagatgatat gtattcagtg ctgccagaag accgctcaca gcaccttgga gaggagttgc    300

aagggttctg ggataaagaa gttttaagag ctgagaatga cgcacagaag ccttctttaa    360

caagagcaat cataaagtgt tactggaaat cttatttagt tttgggaatt tttacgttaa    420

ttgaggaaag tgccaaagta atccagccca tatttttggg aaaaattatt aattattttg    480

aaaattatga tcccatggat tctgtggctt tgaacacagc gtacgcctat gccacggtgc    540

tgactttttg cacgctcatt ttggctatac tgcatcactt atatttttat cacgttcagt    600

gtgctgggat gaggttacga gtagccatgt gccatatgat ttatcggaag gcacttcgtc    660

ttagtaacat ggccatgggg aagacaacca caggccagat agtcaatctg ctgtccaatg    720

atgtgaacaa gtttgatcag gtgacagtgt tcttacactt cctgtgggca ggaccactgc    780

aggcgattgc agtgactgcc ctactctgga tggagatagg aatatcgtgc cttgctggga    840

tggcagttct aatcattctc ctgcccttgc aaagctgttt tgggaagttg ttctcatcac    900

tgaggagtaa aactgcaact ttcacggatg ccaggatcag gaccatgaat gaagttataa    960

ctggtataag gataataaaa atgtacgcct gggaaaagtc attttcaaat cttattacca   1020

atttgagaaa gaaggagatt tccaagattc tgagaagttc ctgcctcaga gggatgaatt   1080

tggcttcatt tttcagtgca agcaaaatca tcgtgtttgt gaccttcacc acctacgtgc   1140

tcctcggcag tgtgatcaca gccagccgcg tgttcgtggc agtgacgctg tatggggctg   1200

tgcggctgac ggttaccctc ttcttcccct cagccattga gagggtgtca gaggcaatcg   1260

tcagcatccg aagaatccag acctttttgc tacttgatga gatatcacag cgcaaccgtc   1320

agctgccgtc agatggtaaa aagatggtgc atgtgcagga ttttactgct ttttgggata   1380

aggcatcaga gaccccaact ctacaaggcc tttcctttac tgtcagacct ggcgaattgt   1440

tagctgtggt cggccccgtg ggagcaggga agtcatcact gttaagtgcc gtgctcgggg   1500

aattggcccc aagtcacggg ctggtcagcg tgcatggaag aattgcctat gtgtctcagc   1560

agccctgggt gttctcggga actctgagga gtaatatttt atttgggaag aaatacgaaa   1620

aggaacgata tgaaaaagtc ataaaggctt gtgctctgaa aaaggattta cagctgttgg   1680

aggatggtga tctgactgtg ataggagatc ggggaaccac gctgagtgga gggcagaaag   1740

cacgggtaaa ccttgcaaga gcagtgtatc aagatgctga catctatctc ctggacgatc   1800

ctctcagtgc agtagatgcg gaagttagca gacacttgtt cgaactgtgt atttgtcaaa   1860

ttttgcatga gaagatcaca attttagtga ctcatcagtt gcagtacctc aaagctgcaa   1920

gtcagattct gatattgaaa gatggtaaaa tggtgcagaa ggggacttac actgagttcc   1980

taaaatctgg tatagatttt ggctcccttt taaagaagga taatgaggaa agtgaacaac   2040

ctccagttcc aggaactccc acactaagga atcgtacctt ctcagagtct tcggtttggt   2100

ctcaacaatc ttctagaccc tccttgaaag atggtgctct ggagagccaa gatacagaga   2160

atgtcccagt tacactatca gaggagaacc gttctgaagg aaaagttggt tttcaggcct   2220

ataagaatta cttcagagct ggtgctcact ggattgtctt cattttcctt attctcctaa   2280

acactgcagc tcaggttgcc tatgtgcttc aagattggtg gctttcatac tgggcaaaca   2340

aacaaagtat gctaaatgtc actgtaaatg gaggaggaaa tgtaaccgag aagctagatc   2400

ttaactggta cttaggaatt tattcaggtt taactgtagc taccgttctt tttggcatag   2460

caagatctct attggtattc tacgtccttg ttaactcttc acaaactttg cacaacaaaa   2520

tgtttgagtc aattctgaaa gctccggtat tattctttga tagaaatcca ataggaagaa   2580

ttttaaatcg tttctccaaa gacattggac acttggatga tttgctgccg ctgacgtttt   2640

tagatttcat ccagagatgg gatctcgctg tgttgtcctg gctggtctca aactcctagg   2700

ctcaagcaat cctcctccct cctcaagcaa acctcagtgc tgggattata ggcatgagcc   2760

actgtacctg gctaaatgtt gtttttttga tattcaattt ttgtttatag aattttcatt   2820

tgttttgctc ttatactttt catcttttta tgtttattga ccaattaaat atcatttggg   2880

taagcacct                                                           2889


<210>  8377
<211>  859
<212>  PRT
<213>  Homo sapiens

<400>  8377

Met Leu Pro Val Tyr Gln Glu Val Lys Pro Asn Pro Leu Gln Asp Ala 
1               5                   10                  15


Asn Leu Cys Ser Arg Val Phe Phe Trp Trp Leu Asn Pro Leu Phe Lys 
            20                  25                  30


Ile Gly His Lys Arg Arg Leu Glu Glu Asp Asp Met Tyr Ser Val Leu 
        35                  40                  45


Pro Glu Asp Arg Ser Gln His Leu Gly Glu Glu Leu Gln Gly Phe Trp 
    50                  55                  60


Asp Lys Glu Val Leu Arg Ala Glu Asn Asp Ala Gln Lys Pro Ser Leu 
65                  70                  75                  80


Thr Arg Ala Ile Ile Lys Cys Tyr Trp Lys Ser Tyr Leu Val Leu Gly 
                85                  90                  95


Ile Phe Thr Leu Ile Glu Glu Ser Ala Lys Val Ile Gln Pro Ile Phe 
            100                 105                 110


Leu Gly Lys Ile Ile Asn Tyr Phe Glu Asn Tyr Asp Pro Met Asp Ser 
        115                 120                 125


Val Ala Leu Asn Thr Ala Tyr Ala Tyr Ala Thr Val Leu Thr Phe Cys 
    130                 135                 140


Thr Leu Ile Leu Ala Ile Leu His His Leu Tyr Phe Tyr His Val Gln 
145                 150                 155                 160


Cys Ala Gly Met Arg Leu Arg Val Ala Met Cys His Met Ile Tyr Arg 
                165                 170                 175


Lys Ala Leu Arg Leu Ser Asn Met Ala Met Gly Lys Thr Thr Thr Gly 
            180                 185                 190


Gln Ile Val Asn Leu Leu Ser Asn Asp Val Asn Lys Phe Asp Gln Val 
        195                 200                 205


Thr Val Phe Leu His Phe Leu Trp Ala Gly Pro Leu Gln Ala Ile Ala 
    210                 215                 220


Val Thr Ala Leu Leu Trp Met Glu Ile Gly Ile Ser Cys Leu Ala Gly 
225                 230                 235                 240


Met Ala Val Leu Ile Ile Leu Leu Pro Leu Gln Ser Cys Phe Gly Lys 
                245                 250                 255


Leu Phe Ser Ser Leu Arg Ser Lys Thr Ala Thr Phe Thr Asp Ala Arg 
            260                 265                 270


Ile Arg Thr Met Asn Glu Val Ile Thr Gly Ile Arg Ile Ile Lys Met 
        275                 280                 285


Tyr Ala Trp Glu Lys Ser Phe Ser Asn Leu Ile Thr Asn Leu Arg Lys 
    290                 295                 300


Lys Glu Ile Ser Lys Ile Leu Arg Ser Ser Cys Leu Arg Gly Met Asn 
305                 310                 315                 320


Leu Ala Ser Phe Phe Ser Ala Ser Lys Ile Ile Val Phe Val Thr Phe 
                325                 330                 335


Thr Thr Tyr Val Leu Leu Gly Ser Val Ile Thr Ala Ser Arg Val Phe 
            340                 345                 350


Val Ala Val Thr Leu Tyr Gly Ala Val Arg Leu Thr Val Thr Leu Phe 
        355                 360                 365


Phe Pro Ser Ala Ile Glu Arg Val Ser Glu Ala Ile Val Ser Ile Arg 
    370                 375                 380


Arg Ile Gln Thr Phe Leu Leu Leu Asp Glu Ile Ser Gln Arg Asn Arg 
385                 390                 395                 400


Gln Leu Pro Ser Asp Gly Lys Lys Met Val His Val Gln Asp Phe Thr 
                405                 410                 415


Ala Phe Trp Asp Lys Ala Ser Glu Thr Pro Thr Leu Gln Gly Leu Ser 
            420                 425                 430


Phe Thr Val Arg Pro Gly Glu Leu Leu Ala Val Val Gly Pro Val Gly 
        435                 440                 445


Ala Gly Lys Ser Ser Leu Leu Ser Ala Val Leu Gly Glu Leu Ala Pro 
    450                 455                 460


Ser His Gly Leu Val Ser Val His Gly Arg Ile Ala Tyr Val Ser Gln 
465                 470                 475                 480


Gln Pro Trp Val Phe Ser Gly Thr Leu Arg Ser Asn Ile Leu Phe Gly 
                485                 490                 495


Lys Lys Tyr Glu Lys Glu Arg Tyr Glu Lys Val Ile Lys Ala Cys Ala 
            500                 505                 510


Leu Lys Lys Asp Leu Gln Leu Leu Glu Asp Gly Asp Leu Thr Val Ile 
        515                 520                 525


Gly Asp Arg Gly Thr Thr Leu Ser Gly Gly Gln Lys Ala Arg Val Asn 
    530                 535                 540


Leu Ala Arg Ala Val Tyr Gln Asp Ala Asp Ile Tyr Leu Leu Asp Asp 
545                 550                 555                 560


Pro Leu Ser Ala Val Asp Ala Glu Val Ser Arg His Leu Phe Glu Leu 
                565                 570                 575


Cys Ile Cys Gln Ile Leu His Glu Lys Ile Thr Ile Leu Val Thr His 
            580                 585                 590


Gln Leu Gln Tyr Leu Lys Ala Ala Ser Gln Ile Leu Ile Leu Lys Asp 
        595                 600                 605


Gly Lys Met Val Gln Lys Gly Thr Tyr Thr Glu Phe Leu Lys Ser Gly 
    610                 615                 620


Ile Asp Phe Gly Ser Leu Leu Lys Lys Asp Asn Glu Glu Ser Glu Gln 
625                 630                 635                 640


Pro Pro Val Pro Gly Thr Pro Thr Leu Arg Asn Arg Thr Phe Ser Glu 
                645                 650                 655


Ser Ser Val Trp Ser Gln Gln Ser Ser Arg Pro Ser Leu Lys Asp Gly 
            660                 665                 670


Ala Leu Glu Ser Gln Asp Thr Glu Asn Val Pro Val Thr Leu Ser Glu 
        675                 680                 685


Glu Asn Arg Ser Glu Gly Lys Val Gly Phe Gln Ala Tyr Lys Asn Tyr 
    690                 695                 700


Phe Arg Ala Gly Ala His Trp Ile Val Phe Ile Phe Leu Ile Leu Leu 
705                 710                 715                 720


Asn Thr Ala Ala Gln Val Ala Tyr Val Leu Gln Asp Trp Trp Leu Ser 
                725                 730                 735


Tyr Trp Ala Asn Lys Gln Ser Met Leu Asn Val Thr Val Asn Gly Gly 
            740                 745                 750


Gly Asn Val Thr Glu Lys Leu Asp Leu Asn Trp Tyr Leu Gly Ile Tyr 
        755                 760                 765


Ser Gly Leu Thr Val Ala Thr Val Leu Phe Gly Ile Ala Arg Ser Leu 
    770                 775                 780


Leu Val Phe Tyr Val Leu Val Asn Ser Ser Gln Thr Leu His Asn Lys 
785                 790                 795                 800


Met Phe Glu Ser Ile Leu Lys Ala Pro Val Leu Phe Phe Asp Arg Asn 
                805                 810                 815


Pro Ile Gly Arg Ile Leu Asn Arg Phe Ser Lys Asp Ile Gly His Leu 
            820                 825                 830


Asp Asp Leu Leu Pro Leu Thr Phe Leu Asp Phe Ile Gln Arg Trp Asp 
        835                 840                 845


Leu Ala Val Leu Ser Trp Leu Val Ser Asn Ser 
    850                 855


<210>  8378
<211>  324
<212>  DNA
<213>  Homo sapiens

<400>  8378
ccagttgtct cccaggtgga tggaaagagg acattttgct ttgcaagggt ctctcttcaa     60

aaggttcaaa tttcgtgcag cttctggaaa ttctccatct tgatcatcgt accgtggagc    120

tgtgccacca tctccgtgat ctctgccaaa gcggctgtga aggaaagaca tacacagtct    180

gcagcgggaa aggcaggcag gggtcttccc ctagcagctg tcagctcaac gctgcaggga    240

aatcactcca gtccctgcac agtattcaaa ggtgtctttt gagcaaaaac agtgctattt    300

ctctataata aaaattgatg gtgt                                           324


<210>  8379
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  8379

Ser Cys Leu Pro Gly Gly Trp Lys Glu Asp Ile Leu Leu Cys Lys Gly 
1               5                   10                  15


Leu Ser Ser Lys Gly Ser Asn Phe Val Gln Leu Leu Glu Ile Leu His 
            20                  25                  30


Leu Asp His Arg Thr Val Glu Leu Cys His His Leu Arg Asp Leu Cys 
        35                  40                  45


Gln Ser Gly Cys Glu Gly Lys Thr Tyr Thr Val Cys Ser Gly Lys Gly 
    50                  55                  60


Arg Gln Gly Ser Ser Pro Ser Ser Cys Gln Leu Asn Ala Ala Gly Lys 
65                  70                  75                  80


Ser Leu Gln Ser Leu His Ser Ile Gln Arg Cys Leu Leu Ser Lys Asn 
                85                  90                  95


Ser Ala Ile Ser Leu 
            100


<210>  8380
<211>  560
<212>  DNA
<213>  Homo sapiens

<400>  8380
aggggcaccc agagagatgg aatgaggcag actcggaggt ctgtattttt tattgtggta     60

aaatagctat accacaatat tggccaactt aacgattttt acgggaacaa ttcagtggca    120

ttaagtgcct ttacaaggtg gtgcaactgc tttgagtctc tgctggtgat gtcactttgg    180

caaagggacg aaatgagcca ccagtgcgtc aggcctgctc agagttgttt ggaggtagca    240

tggacacagg tgcctgtccc tgccccctag ctgggctgca gcgcatccta acaatgctcc    300

aggggctggg ccggccctga gcctggaggt gggcagggct gcaactgcct cctgggccac    360

tagagggcat gtgggagcca ctcacatgca ccccaggccc cacttcctgg gtagggtgcc    420

tggcccctca aaacgagtgc tgctctgagc ttgttgggat ggatctttcc ctccttcagc    480

ttccgcctgc tggcaatgca tggggtcctg cgcccccatt tctgcctcgg tgtcacaggg    540

cacacccctc tccccccaag                                                560


<210>  8381
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8381

Met Trp Glu Pro Leu Thr Cys Thr Pro Gly Pro Thr Ser Trp Val Gly 
1               5                   10                  15


Cys Leu Ala Pro Gln Asn Glu Cys Cys Ser Glu Leu Val Gly Met Asp 
            20                  25                  30


Leu Ser Leu Leu Gln Leu Pro Pro Ala Gly Asn Ala Trp Gly Pro Ala 
        35                  40                  45


Pro Pro Phe Leu Pro Arg Cys His Arg Ala His Pro Ser Pro Pro 
    50                  55                  60


<210>  8382
<211>  1407
<212>  DNA
<213>  Homo sapiens

<400>  8382
aggtggatgg aagtgatccg cagtgccacc agctctgcct cgcgacccca cgtgttgagt     60

cacaaagagt ctcttgtgta ttgatggccg gacacactcg tttccgcagt ggctgctttc    120

ctggaagacg tttcctttct tctgtattaa tgaagcctgg taaaattaac acctgtctga    180

aaatcaaaaa catggcttcc cagcagctct cctgtctcca cagccgcgtt ttttaacccc    240

gacctctcag cgtctgaatg aacagcgctc ccacctccag tcctggcatc cgctgggggc    300

gctgttcttt agctagtgcc agtattaaaa cattgtcatt acgagagtgc caaatgacat    360

cttccctcca ccctgcccct gaaaaacagt acacacacat ccgttcaaca caagacaggg    420

caagtgtttt tcttcctaaa aaaagttctt tcttttatta ttttcaccta ttggctgctg    480

cattttacga agtggacttc ccggtgtttg tttgtttgtt tgcaatacac tcagtgcagc    540

cttaagcaaa tgagatcatt ttcagatttc attttttttt tcagtctttc tacttttgta    600

ataataggaa gttagtagga ctcacttctc tgattaataa gcaatttgca gcacacagcg    660

ttccactgcg gggtttcacg ctcacctgaa aacacctgtt cccaacctac ttcttggtgc    720

aagttgacca aatcgtttta agtggtaact ctttccaacc gtagcagggt tgttttctgt    780

taagcaaagc cgagatccag tgcaatacct ggactgtcac cgtcctgtga gtggtgtaca    840

caatgggaag ataataagcc gtggtgtttt gctgtctgtc tgtgtcacaa gcatgaaaac    900

ccgtgtgtca ttgatcagca ccatttgtgg tatgttccgt gatgagcgtt tagtgagcct    960

gctggctgca gagcactatg aaatcatggc atggggtagt gtcagtcgga ctgcacaggg   1020

aacacggttt ccagtggctt tggcccctac tcgggaaacg tctgcctgtt ctcgatggtg   1080

atggggtggc tgccattccc ttggttttcc taagcccttt ctaacgagag tctcaaacaa   1140

gcggaggcga gggccaattc aaccccattc tttccagcgc cccgcaccat agcacctgcc   1200

cacctgagaa ccaggaacgc accctctctg tggagctctg actggtgtag ctggaaacaa   1260

acagcaactt gcaaacggac gaagagcctg ccgtgtgtta atcatttgcc ttacaagatg   1320

taccagacgg tttccagtac taacaaaggg aataaaaata cctcacgcca caatccagca   1380

tattgatgtt ttaaggcaaa acaacca                                       1407


<210>  8383
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  8383

Met Lys Thr Arg Val Ser Leu Ile Ser Thr Ile Cys Gly Met Phe Arg 
1               5                   10                  15


Asp Glu Arg Leu Val Ser Leu Leu Ala Ala Glu His Tyr Glu Ile Met 
            20                  25                  30


Ala Trp Gly Ser Val Ser Arg Thr Ala Gln Gly Thr Arg Phe Pro Val 
        35                  40                  45


Ala Leu Ala Pro Thr Arg Glu Thr Ser Ala Cys Ser Arg Trp 
    50                  55                  60


<210>  8384
<211>  1129
<212>  DNA
<213>  Homo sapiens

<400>  8384
cggacacact cgtttccgca gtggctgctt tcctggaaga cgtttccttt cttctgtatt     60

aatgaagcct ggtaaaatta acacctgtct gaaaatcaaa aacatggctt cccagcagct    120

ctcctgtctc cacagccgcg ttttttaacc ccgacctctc agcgtctgaa tgaacagcgc    180

tcccacctcc agtcctggca tccgctgggg gcgctgttct ttagctagtg ccagtattaa    240

aacattgtca ttacgagagt gccaaatgac atcttccctc caccctgccc ctgaaaaaca    300

gtacacacac atccgttcaa cacaagacag ggcaagtgtt tttcttccta aaaaaagttc    360

tttcttttat tattttcacc tattggctgc tgcattttac gaagtggact tcccggtgtt    420

tgtttgtttg tttgcaatac actcagtgca gccttaagca aatgagatca ttttcagatt    480

tcattttttt tttcagtctt tctacttttg taataatagg aagttagtag gactcacttc    540

tctgattaat aagcaatttg cagcacacag cgttccactg cggggtttca cgctcacctg    600

aaaacacctg ttcccaacct acttcttggt gcaagttgac caaatcgttt taagtggtaa    660

ctctttccaa ccgtagcagg gttgttttct gttaagcaaa gccgagatcc agtgcaatac    720

ctggactgtc accgtcctgt gagtggtgta cacaatggga agataataag ccgtggtgtt    780

ttgctgtctg tctgtgtcac aagcatgaaa acccgtgtgt cattgatcag caccatttgt    840

ggtatgttcc gtgatgagcg tttagtgagc ctgctggctg cagagcacta tgaaatcatg    900

cgccccgcac catagcacct gcccacctga gaaccaggaa cgcaccctct ctgtggagct    960

ctgactggtg tagctggaaa caaacagcaa cttgcaaacg gacgaagagc ctgccgtgtg   1020

ttaatcattt gccttacaag atgtaccaga cggtttccag tactaacaaa gggaataaaa   1080

atacctcacg ccacaatcca gcatattgat gttttaaggc aaaacaacc               1129


<210>  8385
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  8385

Met Lys Thr Arg Val Ser Leu Ile Ser Thr Ile Cys Gly Met Phe Arg 
1               5                   10                  15


Asp Glu Arg Leu Val Ser Leu Leu Ala Ala Glu His Tyr Glu Ile Met 
            20                  25                  30


Arg Pro Ala Pro 
        35


<210>  8386
<211>  3292
<212>  DNA
<213>  Homo sapiens

<400>  8386
tttggcgtgg ctggccagct gacagacacc cagatcaaaa ggaacacctt cccatcggac     60

ttggacagaa ataagatgaa agacatcccg aagaggcctt tctctcagtg tttatctaca    120

attatttctc ctctgtttgc agagttgaag gagaagagcc aggcgtgcgg agggaacttg    180

gggtccattg aagagctgcg aggggccatc tacctagcgg aggaggcgtg ccctggcatc    240

tccgacacca tggtggccca gctcgtgcag cggctccaga gatactctct aagtggtgga    300

ggaacttcat cccactgaaa ttcctttggc atttggggtt ttgtttttcc ttttttcctt    360

cttcatcctc ctcctttttt aaaagtcaac gagagccttc gctgactcca ccgaagaggt    420

gcgccactgg gagccacccc agcgccaggc gcccgtccag ggacacacac agtcttcact    480

gtgctgcagc cagatgaagt ctctcagatg ggtggggagg gtcagctcct tccagcgatc    540

attttatttt attttattac ttttgttttt aattttaacc atagtgcaca tattccagga    600

aagtgtcttt aaaaacaaaa acaaaccctg aaatgtatat ttgggattat gataaggcaa    660

ctaaagacat gaaacctcag gtatcctgct ttaagttgat aactccctct gggagctgga    720

gaatcgctct ggtggatggg tgtacagatt tgtatataat gtcattttta cggaaaccct    780

ttcggcgtgc ataaggaatc actgtgtaca aactggccaa gtgcttctgt agataacgtc    840

agtggagtaa atattcgaca ggccataact tgagtctatt gccttgcctt tattacatgt    900

acattttgaa ttctgtgacc agtgatttgg gttttatttt gtatttgcag ggtttgtcat    960

taataattaa tgcccctctc ttacagaaca ctcctatttg tacctcaaca aatgcaaatt   1020

ttccccgttt gccctacgcc ccttttggta cacctagagg ttgatttcct ttttcatcga   1080

tggtactatt tcttagtgtt ttaaattgga acatatcttg cctcatgaag ctttaaatta   1140

taattttcag tttctcccca tgaagcgctc tcgtctgaca tttgtttgga atcgtgccac   1200

tgctggtctg cgccagatgt accgtccttt ccaatacgat tttctgttgc accttgtagt   1260

ggattctgca tatcatcttt cccacctaaa aatgtctgaa tgcttacaca aataaatttt   1320

ataacacgct tattttgcat actccttgaa atgtgactct tcagaggaca gggcacctgc   1380

tgtgtatgtg tggccgtgcg tgtgtactcg tggctgtgtg tgtgtgatga gacactttgg   1440

aagactccag ggagaagtcc ccaggcctgg agctgccgag tgcccaggtc agcgccctgg   1500

actgcttgcg cacttgctca ccgagatgat gcagttggag gttgctgatc tgtgcgattg   1560

ctgtagcggt tgccggggac cttaagagtt attttgcttc tctggaaggg gcctatgctt   1620

gctaggcagg cagccagtgt gtctgttttt cttggtttgc tgtgggacct tgcttggcga   1680

gggggaaaat ctctgggttt ctggagtggg agggttcgtg cagcagctgt tgactggtac   1740

atgaagcatt cttttatgtt tgttgaagct gatgattgac atctcccgtg ggtgtgccag   1800

ttcttgtgga gttaagacag gatttttgga agcaaggaag ttagtgggtg agcttgggga   1860

tgtagctcag ctatctgctg gtctagtggc ctctaagcta tagggagggg acagagccct   1920

gagctacaga tgcttgagtg ggttattgtg tcggtttgct agtgcagtct ggtttttaag   1980

ctctaaaatt gaggtatttt attagaagtg gatttgggtt gaactcttaa tttgtataag   2040

ggatatattt tggttgggga aatagaactg agttgctaat tcttattgta ctcattactc   2100

catacaagaa tgttatgttg aataataaaa ttggagaaga tttcattttg tgtttccagg   2160

gagtattctg tgtggggaac tgtttcctta cgtgaggccg gcggcataag tcaaagatga   2220

gttttgtcct tgcgaatcac acagattgag tctgtgttcc ccagggtgtg ccgttacctg   2280

atttttaagt gagccagggc ggacagcagc ttttctgatt tacagagttc ttcagattta   2340

caaatggaca atgacatcac agtttttagc actgaagcca gtctcatgct agtaacagtg   2400

ggtgagccgc tcgagggact gggttctaat gaatactggt atgaacgggg agtctctgca   2460

gtcgccagac aaatcatact cagccccttc ccccgtagag caacaagtgg ttcttttaga   2520

gttgactggc agcatttcct gtcgggggag gtggggtttg atggagttag aaagctcgcc   2580

tctgtgtaca ttctctcctg ggctgttact ttctgtagac gcacaaaatc agccccaatg   2640

tttttaaggg catcttagcc aaggaagctg gcttttgtgt cgccacttcc aggcctgcat   2700

taagagagag cccaggcacc agggctacca ctggaacctg cctcagcgtc aactgctgct   2760

ggtctgtagc caggcccagc ctttgagacg ggtttactgt caccagtagc ctctcagtgc   2820

cagccctgag ctgctcctgg ctcagctgcc cagagcctgc agcctgggga ggtactcagc   2880

ctctgggaga cgagggccgt ggactgggtg gctggtagct cctgcgtttt tgagctgtgt   2940

cctggctggc tgctgccaat gaggtggaca ccagtgtggt ttggggtgca ctggccactt   3000

cttgctgggt tctgattttc ttggaagtgc atctgccttc cttatccaat agttttatcc   3060

ctgcattgct cttgtgaagt ggctggtttg gttctgtatg tagcattttg tacctttcct   3120

ctggcaaaac actgtcagtt tataaacatt ttttatattt ccctccttta aaaacagctt   3180

gtgtatttct gctataaaat gtgtcagcaa aggcagagtg acctaatagg gcatgttctt   3240

aagcacaggg actgtatcat gcaggggcca ataaagctca agaaaacgag ta           3292


<210>  8387
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  8387

Met Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile 
1               5                   10                  15


Ile Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly 
            20                  25                  30


Gly Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala 
        35                  40                  45


Glu Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val 
    50                  55                  60


Gln Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
65                  70                  75                  80


<210>  8388
<211>  4635
<212>  DNA
<213>  Homo sapiens

<400>  8388
gggacgcgct cggcgctcgc gggctcggcg ggctgtgcgc gcccactccg gctccagcgg     60

ccagcgcgcg cgggcccagg ccgcccggct ccagcccagc agtagcggca gcagcggcgg    120

cggcggcagt gcgcgcgagg ccctgcgccc ccagcagctc ctccctggcg ccgtgcatgg    180

agacgcggcc cgccacccgc cgctgagccc ccgccgcccg gccgggaccc gccagggctg    240

gggtggcctc gggctccggc cggccccgcc gcccgagggc tgcgcgcggc ccgcgggcct    300

cgccgccccg cgcggatcgt cgcggcccgg ccgtcccgtc ccaggaagtg gccgtcctga    360

gcgccatggc tcactccccg gtgcagtcgg gcctgcccgg catgcagaac ctaaaggcag    420

acccagaaga gctttttaca aaactagaga aaattgggaa gggctccttt ggagaggtgt    480

tcaaaggcat tgacaatcgg actcagaaag tggttgccat aaagatcatt gatctggaag    540

aagctgaaga tgagatagag gacattcaac aagaaatcac agtgctgagt cagtgtgaca    600

gtccatatgt aaccaaatat tatggatcct atctgaagga tacaaaatta tggataataa    660

tggaatatct tggtggaggc tccgcactag atctattaga acctggccca ttagatgaaa    720

cccagatcgc tactatatta agagaaatac tgaaaggact cgattatctc cattcggaga    780

agaaaatcca cagagacatt aaagcggcca acgtcctgct gtctgagcat ggcgaggtga    840

agctggcgga ctttggcgtg gctggccagc tgacagacac ccagatcaaa aggaacacct    900

tcgtgggcac cccattctgg atggcacccg aggtcatcaa acagtcggcc tatgactcga    960

aggcagacat ctggtccctg ggcataacag ctattgaact tgcaagaggg gaaccacctc   1020

attccgagct gcaccccatg aaagttttat tcctcattcc aaagaacaac ccaccgacgt   1080

tggaaggaaa ctacagtaaa cccctcaagg agtttgtgga ggcctgtttg aataaggagc   1140

cgagctttag acccactgct aaggagttat tgaagcacaa gtttatacta cgcaatgcaa   1200

agaaaacttc ctacttgacc gagctcatcg acaggtacaa gagatggaag gccgagcaga   1260

gccatgacga ctcgagctcc gaggattccg acgcggaaac agatggccaa gcctcggggg   1320

gcagtgattc tggggactgg atcttcacaa tccgagaaaa agatcccaag aatctcgaga   1380

atggagctct tcagccatcg gacttggaca gaaataagat gaaagacatc ccgaagaggc   1440

ctttctctca gtgtttatct acaattattt ctcctctgtt tgcagagttg aaggagaaga   1500

gccaggcgtg cggagggaac ttggggtcca ttgaagagct gcgaggggcc atctacctag   1560

cggaggaggc gtgccctggc atctccgaca ccatggtggc ccagctcgtg cagcggctcc   1620

agagatactc tctaagtggt ggaggaactt catcccactg aaattccttt ggcatttggg   1680

gttttgtttt tccttttttc cttcttcatc ctcctccttt tttaaaagtc aacgagagcc   1740

ttcgctgact ccaccgaaga ggtgcgccac tgggagccac cccagcgcca ggcgcccgtc   1800

cagggacaca cacagtcttc actgtgctgc agccagatga agtctctcag atgggtgggg   1860

agggtcagct ccttccagcg atcattttat tttattttat tacttttgtt tttaatttta   1920

accatagtgc acatattcca ggaaagtgtc tttaaaaaca aaaacaaacc ctgaaatgta   1980

tatttgggat tatgataagg caactaaaga catgaaacct caggtatcct gctttaagtt   2040

gataactccc tctgggagct ggagaatcgc tctggtggat gggtgtacag atttgtatat   2100

aatgtcattt ttacggaaac cctttcggcg tgcataagga atcactgtgt acaaactggc   2160

caagtgcttc tgtagataac gtcagtggag taaatattcg acaggccata acttgagtct   2220

attgccttgc ctttattaca tgtacatttt gaattctgtg accagtgatt tgggttttat   2280

tttgtatttg cagggtttgt cattaataat taatgcccct ctcttacaga acactcctat   2340

ttgtacctca acaaatgcaa attttccccg tttgccctac gccccttttg gtacacctag   2400

aggttgattt cctttttcat cgatggtact atttcttagt gttttaaatt ggaacatatc   2460

ttgcctcatg aagctttaaa ttataatttt cagtttctcc ccatgaagcg ctctcgtctg   2520

acatttgttt ggaatcgtgc cactgctggt ctgcgccaga tgtaccgtcc tttccaatac   2580

gattttctgt tgcaccttgt agtggattct gcatatcatc tttcccacct aaaaatgtct   2640

gaatgcttac acaaataaat tttataacac gcttattttg catactcctt gaaatgtgac   2700

tcttcagagg acagggcacc tgctgtgtat gtgtggccgt gcgtgtgtac tcgtggctgt   2760

gtgtgtgtga tgagacactt tggaagactc cagggagaag tccccaggcc tggagctgcc   2820

gagtgcccag gtcagcgccc tggactgctt gcgcacttgc tcaccgagat gatgcagttg   2880

gaggttgctg atctgtgcga ttgctgtagc ggttgccggg gaccttaaga gttattttgc   2940

ttctctggaa ggggcctatg cttgctaggc aggcagccag tgtgtctgtt tttcttggtt   3000

tgctgtggga ccttgcttgg cgagggggaa aatctctggg tttctggagt gggagggttc   3060

gtgcagcagc tgttgactgg tacatgaagc attcttttat gtttgttgaa gctgatgatt   3120

gacatctccc gtgggtgtgc cagttcttgt ggagttaaga caggattttt ggaagcaagg   3180

aagttagtgg gtgagcttgg ggatgtagct cagctatctg ctggtctagt ggcctctaag   3240

ctatagggag gggacagagc cctgagctac agatgcttga gtgggttatt gtgtcggttt   3300

gctagtgcag tctggttttt aagctctaaa attgaggtat tttattagaa gtggatttgg   3360

gttgaactct taatttgtat aagggatata ttttggttgg ggaaatagaa ctgagttgct   3420

aattcttatt gtactcatta ctccatacaa gaatgttatg ttgaataata aaattggaga   3480

agatttcatt ttgtgtttcc agggagtatt ctgtgtgggg aactgtttcc ttacgtgagg   3540

ccggcggcat aagtcaaaga tgagttttgt ccttgcgaat cacacagatt gagtctgtgt   3600

tccccagggt gtgccgttac ctgattttta agtgagccag ggcggacagc agcttttctg   3660

atttacagag ttcttcagat ttacaaatgg acaatgacat cacagttttt agcactgaag   3720

ccagtctcat gctagtaaca gtgggtgagc cgctcgaggg actgggttct aatgaatact   3780

ggtatgaacg gggagtctct gcagtcgcca gacaaatcat actcagcccc ttcccccgta   3840

gagcaacaag tggttctttt agagttgact ggcagcattt cctgtcgggg gaggtggggt   3900

ttgatggagt tagaaagctc gcctctgtgt acattctctc ctgggctgtt actttctgta   3960

gacgcacaaa atcagcccca atgtttttaa gggcatctta gccaaggaag ctggcttttg   4020

tgtcgccact tccaggcctg cattaagaga gagcccaggc accagggcta ccactggaac   4080

ctgcctcagc gtcaactgct gctggtctgt agccaggccc agcctttgag acgggtttac   4140

tgtcaccagt agcctctcag tgccagccct gagctgctcc tggctcagct gcccagagcc   4200

tgcagcctgg ggaggtactc agcctctggg agacgagggc cgtggactgg gtggctggta   4260

gctcctgcgt ttttgagctg tgtcctggct ggctgctgcc aatgaggtgg acaccagtgt   4320

ggtttggggt gcactggcca cttcttgctg ggttctgatt ttcttggaag tgcatctgcc   4380

ttccttatcc aatagtttta tccctgcatt gctcttgtga agtggctggt ttggttctgt   4440

atgtagcatt ttgtaccttt cctctggcaa aacactgtca gtttataaac attttttata   4500

tttccctcct ttaaaaacag cttgtgtatt tctgctataa aatgtgtcag caaaggcaga   4560

gtgacctaat agggcatgtt cttaagcaca gggactgtat catgcagggg ccaataaagc   4620

tcaagaaaac gagta                                                    4635


<210>  8389
<211>  431
<212>  PRT
<213>  Homo sapiens

<400>  8389

Met Ala His Ser Pro Val Gln Ser Gly Leu Pro Gly Met Gln Asn Leu 
1               5                   10                  15


Lys Ala Asp Pro Glu Glu Leu Phe Thr Lys Leu Glu Lys Ile Gly Lys 
            20                  25                  30


Gly Ser Phe Gly Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Lys 
        35                  40                  45


Val Val Ala Ile Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile 
    50                  55                  60


Glu Asp Ile Gln Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Pro 
65                  70                  75                  80


Tyr Val Thr Lys Tyr Tyr Gly Ser Tyr Leu Lys Asp Thr Lys Leu Trp 
                85                  90                  95


Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Glu 
            100                 105                 110


Pro Gly Pro Leu Asp Glu Thr Gln Ile Ala Thr Ile Leu Arg Glu Ile 
        115                 120                 125


Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp 
    130                 135                 140


Ile Lys Ala Ala Asn Val Leu Leu Ser Glu His Gly Glu Val Lys Leu 
145                 150                 155                 160


Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg 
                165                 170                 175


Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Lys 
            180                 185                 190


Gln Ser Ala Tyr Asp Ser Lys Ala Asp Ile Trp Ser Leu Gly Ile Thr 
        195                 200                 205


Ala Ile Glu Leu Ala Arg Gly Glu Pro Pro His Ser Glu Leu His Pro 
    210                 215                 220


Met Lys Val Leu Phe Leu Ile Pro Lys Asn Asn Pro Pro Thr Leu Glu 
225                 230                 235                 240


Gly Asn Tyr Ser Lys Pro Leu Lys Glu Phe Val Glu Ala Cys Leu Asn 
                245                 250                 255


Lys Glu Pro Ser Phe Arg Pro Thr Ala Lys Glu Leu Leu Lys His Lys 
            260                 265                 270


Phe Ile Leu Arg Asn Ala Lys Lys Thr Ser Tyr Leu Thr Glu Leu Ile 
        275                 280                 285


Asp Arg Tyr Lys Arg Trp Lys Ala Glu Gln Ser His Asp Asp Ser Ser 
    290                 295                 300


Ser Glu Asp Ser Asp Ala Glu Thr Asp Gly Gln Ala Ser Gly Gly Ser 
305                 310                 315                 320


Asp Ser Gly Asp Trp Ile Phe Thr Ile Arg Glu Lys Asp Pro Lys Asn 
                325                 330                 335


Leu Glu Asn Gly Ala Leu Gln Pro Ser Asp Leu Asp Arg Asn Lys Met 
            340                 345                 350


Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile Ile 
        355                 360                 365


Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly Gly 
    370                 375                 380


Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala Glu 
385                 390                 395                 400


Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val Gln 
                405                 410                 415


Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
            420                 425                 430


<210>  8390
<211>  1338
<212>  DNA
<213>  Homo sapiens

<400>  8390
tttggcgtgg ctggccagct gacagacacc cagatcaaaa ggaacacctt cccatcggac     60

ttggacagaa ataagatgaa agacatcccg aagaggcctt tctctcagtg tttatctaca    120

attatttctc ctctgtttgc agagttgaag gagaagagcc aggcgtgcgg agggaacttg    180

gggtccattg aagagctgcg aggggccatc tacctagcgg aggaggcgtg ccctggcatc    240

tccgacacca tggtggccca gctcgtgcag cggctccaga gatactctct aagtggtgga    300

ggaacttcat cccactgaaa ttcctttggc atttggggtt ttgtttttcc ttttttcctt    360

cttcatcctc ctcctttttt aaaagtcaac gagagccttc gctgactcca ccgaagaggt    420

gcgccactgg gagccacccc agcgccaggc gcccgtccag ggacacacac agtcttcact    480

gtgctgcagc cagatgaagt ctctcagatg ggtggggagg gtcagctcct tccagcgatc    540

attttatttt attttattac ttttgttttt aattttaacc atagtgcaca tattccagga    600

aagtgtcttt aaaaacaaaa acaaaccctg aaatgtatat ttgggattat gataaggcaa    660

ctaaagacat gaaacctcag gtatcctgct ttaagttgat aactccctct gggagctgga    720

gaatcgctct ggtggatggg tgtacagatt tgtatataat gtcattttta cggaaaccct    780

ttcggcgtgc ataaggaatc actgtgtaca aactggccaa gtgcttctgt agataacgtc    840

agtggagtaa atattcgaca ggccataact tgagtctatt gccttgcctt tattacatgt    900

acattttgaa ttctgtgacc agtgatttgg gttttatttt gtatttgcag ggtttgtcat    960

taataattaa tgcccctctc ttacagaaca ctcctatttg tacctcaaca aatgcaaatt   1020

ttccccgttt gccctacgcc ccttttggta cacctagagg ttgatttcct ttttcatcga   1080

tggtactatt tcttagtgtt ttaaattgga acatatcttg cctcatgaag ctttaaatta   1140

taattttcag tttctcccca tgaagcgctc tcgtctgaca tttgtttgga atcgtgccac   1200

tgctggtctg cgccagatgt accgtccttt ccaatacgat tttctgttgc accttgtagt   1260

ggattctgca tatcatcttt cccacctaaa aatgtctgaa tgcttacaca aataaatttt   1320

ataacacgct tattttgc                                                 1338


<210>  8391
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  8391

Met Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile 
1               5                   10                  15


Ile Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly 
            20                  25                  30


Gly Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala 
        35                  40                  45


Glu Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val 
    50                  55                  60


Gln Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
65                  70                  75                  80


<210>  8392
<211>  2625
<212>  DNA
<213>  Homo sapiens

<400>  8392
agacacgaca ttgcagcact ggtgaccgga tccagagcgg agccaggctg cagtggtggg     60

gaggaccggg caggtccaga tgactttgaa gggactccag aggaaggaga gagtggagga    120

ggagggcttt gggttaggga gagtgctttc gtttgtttta aatgggagaa actggagcat    180

gttgccaagg gcagagagcc agcagagagg ggtgaatgga agaaggagcg agaagggggt    240

tactgacgaa gccttatcct ggaggagaga aggatggact ccagagccca gctttgggga    300

ctggccttga ataaaaggag ggccactcta cctcatcctg gagggagcac gaacctaaag    360

gcagacccag aagagctttt tacaaaacta gagaaaattg ggaagggctc ctttggagag    420

gtgttcaaag gcattgacaa tcggactcag aaagtggttg ccataaagat cattgatctg    480

gaagaagctg aagatgagat agaggacatt caacaagaaa tcacagtgct gagtcagtgt    540

gacagtccat atgtaaccaa atattatgga tcctatctga aggatacaaa attatggata    600

ataatggaat atcttggtgg aggctccgca ctagatctat tagaacctgg cccattagat    660

gaaacccaga tcgctactat attaagagaa atactgaaag gactcgatta tctccattcg    720

gagaagaaaa tccacagaga cattaaagcg gccaacgtcc tgctgtctga gcatggcgag    780

gtgaagctgg cggactttgg cgtggctggc cagctgacag acacccagat caaaaggaac    840

accttcgtgg gcaccccatt ctggatggca cccgaggtca tcaaacagtc ggcctatgac    900

tcgaaggcag acatctggtc cctgggcata acagctattg aacttgcaag aggggaacca    960

cctcattccg agctgcaccc catgaaagtt ttattcctca ttccaaagaa caacccaccg   1020

acgttggaag gaaactacag taaacccctc aaggagtttg tggaggcctg tttgaataag   1080

gagccgagct ttagacccac tgctaaggag ttattgaagc acaagtttat actacgcaat   1140

gcaaagaaaa cttcctactt gaccgagctc atcgacaggt acaagagatg gaaggccgag   1200

cagagccatg acgactcgag ctccgaggat tccgacgcgg aaacagatgg ccaagcctcg   1260

gggggcagtg attctgggga ctggatcttc acaatccgag aaaaagatcc caagaatctc   1320

gagaatggag ctcttcagcc atcggacttg gacagaaata agatgaaaga catcccgaag   1380

aggcctttct ctcagtgttt atctacaatt atttctcctc tgtttgcaga gttgaaggag   1440

aagagccagg cgtgcggagg gaacttgggg tccattgaag agctgcgagg ggccatctac   1500

ctagcggagg aggcgtgccc tggcatctcc gacaccatgg tggcccagct cgtgcagcgg   1560

ctccagagat actctctaag tggtggagga acttcatccc actgaaattc ctttggcatt   1620

tggggttttg tttttccttt tttccttctt catcctcctc cttttttaaa agtcaacgag   1680

agccttcgct gactccaccg aagaggtgcg ccactgggag ccaccccagc gccaggcgcc   1740

cgtccaggga cacacacagt cttcactgtg ctgcagccag atgaagtctc tcagatgggt   1800

ggggagggtc agctccttcc agcgatcatt ttattttatt ttattacttt tgtttttaat   1860

tttaaccata gtgcacatat tccaggaaag tgtctttaaa aacaaaaaca aaccctgaaa   1920

tgtatatttg ggattatgat aaggcaacta aagacatgaa acctcaggta tcctgcttta   1980

agttgataac tccctctggg agctggagaa tcgctctggt ggatgggtgt acagatttgt   2040

atataatgtc atttttacgg aaaccctttc ggcgtgcata aggaatcact gtgtacaaac   2100

tggccaagtg cttctgtaga taacgtcagt ggagtaaata ttcgacaggc cataacttga   2160

gtctattgcc ttgcctttat tacatgtaca ttttgaattc tgtgaccagt gatttgggtt   2220

ttattttgta tttgcagggt ttgtcattaa taattaatgc ccctctctta cagaacactc   2280

ctatttgtac ctcaacaaat gcaaattttc cccgtttgcc ctacgcccct tttggtacac   2340

ctagaggttg atttcctttt tcatcgatgg tactatttct tagtgtttta aattggaaca   2400

tatcttgcct catgaagctt taaattataa ttttcagttt ctccccatga agcgctctcg   2460

tctgacattt gtttggaatc gtgccactgc tggtctgcgc cagatgtacc gtcctttcca   2520

atacgatttt ctgttgcacc ttgtagtgga ttctgcatat catctttccc acctaaaaat   2580

gtctgaatgc ttacacaaat aaattttata acacgcttat tttgc                   2625


<210>  8393
<211>  443
<212>  PRT
<213>  Homo sapiens

<400>  8393

Met Asp Ser Arg Ala Gln Leu Trp Gly Leu Ala Leu Asn Lys Arg Arg 
1               5                   10                  15


Ala Thr Leu Pro His Pro Gly Gly Ser Thr Asn Leu Lys Ala Asp Pro 
            20                  25                  30


Glu Glu Leu Phe Thr Lys Leu Glu Lys Ile Gly Lys Gly Ser Phe Gly 
        35                  40                  45


Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Lys Val Val Ala Ile 
    50                  55                  60


Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile Glu Asp Ile Gln 
65                  70                  75                  80


Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Pro Tyr Val Thr Lys 
                85                  90                  95


Tyr Tyr Gly Ser Tyr Leu Lys Asp Thr Lys Leu Trp Ile Ile Met Glu 
            100                 105                 110


Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Glu Pro Gly Pro Leu 
        115                 120                 125


Asp Glu Thr Gln Ile Ala Thr Ile Leu Arg Glu Ile Leu Lys Gly Leu 
    130                 135                 140


Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp Ile Lys Ala Ala 
145                 150                 155                 160


Asn Val Leu Leu Ser Glu His Gly Glu Val Lys Leu Ala Asp Phe Gly 
                165                 170                 175


Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg Asn Thr Phe Val 
            180                 185                 190


Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Lys Gln Ser Ala Tyr 
        195                 200                 205


Asp Ser Lys Ala Asp Ile Trp Ser Leu Gly Ile Thr Ala Ile Glu Leu 
    210                 215                 220


Ala Arg Gly Glu Pro Pro His Ser Glu Leu His Pro Met Lys Val Leu 
225                 230                 235                 240


Phe Leu Ile Pro Lys Asn Asn Pro Pro Thr Leu Glu Gly Asn Tyr Ser 
                245                 250                 255


Lys Pro Leu Lys Glu Phe Val Glu Ala Cys Leu Asn Lys Glu Pro Ser 
            260                 265                 270


Phe Arg Pro Thr Ala Lys Glu Leu Leu Lys His Lys Phe Ile Leu Arg 
        275                 280                 285


Asn Ala Lys Lys Thr Ser Tyr Leu Thr Glu Leu Ile Asp Arg Tyr Lys 
    290                 295                 300


Arg Trp Lys Ala Glu Gln Ser His Asp Asp Ser Ser Ser Glu Asp Ser 
305                 310                 315                 320


Asp Ala Glu Thr Asp Gly Gln Ala Ser Gly Gly Ser Asp Ser Gly Asp 
                325                 330                 335


Trp Ile Phe Thr Ile Arg Glu Lys Asp Pro Lys Asn Leu Glu Asn Gly 
            340                 345                 350


Ala Leu Gln Pro Ser Asp Leu Asp Arg Asn Lys Met Lys Asp Ile Pro 
        355                 360                 365


Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile Ile Ser Pro Leu Phe 
    370                 375                 380


Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly Gly Asn Leu Gly Ser 
385                 390                 395                 400


Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala Glu Glu Ala Cys Pro 
                405                 410                 415


Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val Gln Arg Leu Gln Arg 
            420                 425                 430


Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
        435                 440


<210>  8394
<211>  2681
<212>  DNA
<213>  Homo sapiens

<400>  8394
gggacgcgct cggcgctcgc gggctcggcg ggctgtgcgc gcccactccg gctccagcgg     60

ccagcgcgcg cgggcccagg ccgcccggct ccagcccagc agtagcggca gcagcggcgg    120

cggcggcagt gcgcgcgagg ccctgcgccc ccagcagctc ctccctggcg ccgtgcatgg    180

agacgcggcc cgccacccgc cgctgagccc ccgccgcccg gccgggaccc gccagggctg    240

gggtggcctc gggctccggc cggccccgcc gcccgagggc tgcgcgcggc ccgcgggcct    300

cgccgccccg cgcggatcgt cgcggcccgg ccgtcccgtc ccaggaagtg gccgtcctga    360

gcgccatggc tcactccccg gtgcagtcgg gcctgcccgg catgcagaac ctaaaggcag    420

acccagaaga gctttttaca aaactagaga aaattgggaa gggctccttt ggagaggtgt    480

tcaaaggcat tgacaatcgg actcagaaag tggttgccat aaagatcatt gatctggaag    540

aagctgaaga tgagatagag gacattcaac aagaaatcac agtgctgagt cagtgtgaca    600

gtccatatgt aaccaaatat tatggatcct atctgaagga tacaaaatta tggataataa    660

tggaatatct tggtggaggc tccgcactag atctattaga acctggccca ttagatgaaa    720

cccagatcgc tactatatta agagaaatac tgaaaggact cgattatctc cattcggaga    780

agaaaatcca cagagacatt aaagcggcca acgtcctgct gtctgagcat ggcgaggtga    840

agctggcgga ctttggcgtg gctggccagc tgacagacac ccagatcaaa aggaacacct    900

tcgtgggcac cccattctgg atggcacccg aggtcatcaa acagtcggcc tatgactcga    960

aggcagacat ctggtccctg ggcataacag ctattgaact tgcaagaggg gaaccacctc   1020

attccgagct gcaccccatg aaagttttat tcctcattcc aaagaacaac ccaccgacgt   1080

tggaaggaaa ctacagtaaa cccctcaagg agtttgtgga ggcctgtttg aataaggagc   1140

cgagctttag acccactgct aaggagttat tgaagcacaa gtttatacta cgcaatgcaa   1200

agaaaacttc ctacttgacc gagctcatcg acaggtacaa gagatggaag gccgagcaga   1260

gccatgacga ctcgagctcc gaggattccg acgcggaaac agatggccaa gcctcggggg   1320

gcagtgattc tggggactgg atcttcacaa tccgagaaaa agatcccaag aatctcgaga   1380

atggagctct tcagccatcg gacttggaca gaaataagat gaaagacatc ccgaagaggc   1440

ctttctctca gtgtttatct acaattattt ctcctctgtt tgcagagttg aaggagaaga   1500

gccaggcgtg cggagggaac ttggggtcca ttgaagagct gcgaggggcc atctacctag   1560

cggaggaggc gtgccctggc atctccgaca ccatggtggc ccagctcgtg cagcggctcc   1620

agagatactc tctaagtggt ggaggaactt catcccactg aaattccttt ggcatttggg   1680

gttttgtttt tccttttttc cttcttcatc ctcctccttt tttaaaagtc aacgagagcc   1740

ttcgctgact ccaccgaaga ggtgcgccac tgggagccac cccagcgcca ggcgcccgtc   1800

cagggacaca cacagtcttc actgtgctgc agccagatga agtctctcag atgggtgggg   1860

agggtcagct ccttccagcg atcattttat tttattttat tacttttgtt tttaatttta   1920

accatagtgc acatattcca ggaaagtgtc tttaaaaaca aaaacaaacc ctgaaatgta   1980

tatttgggat tatgataagg caactaaaga catgaaacct caggtatcct gctttaagtt   2040

gataactccc tctgggagct ggagaatcgc tctggtggat gggtgtacag atttgtatat   2100

aatgtcattt ttacggaaac cctttcggcg tgcataagga atcactgtgt acaaactggc   2160

caagtgcttc tgtagataac gtcagtggag taaatattcg acaggccata acttgagtct   2220

attgccttgc ctttattaca tgtacatttt gaattctgtg accagtgatt tgggttttat   2280

tttgtatttg cagggtttgt cattaataat taatgcccct ctcttacaga acactcctat   2340

ttgtacctca acaaatgcaa attttccccg tttgccctac gccccttttg gtacacctag   2400

aggttgattt cctttttcat cgatggtact atttcttagt gttttaaatt ggaacatatc   2460

ttgcctcatg aagctttaaa ttataatttt cagtttctcc ccatgaagcg ctctcgtctg   2520

acatttgttt ggaatcgtgc cactgctggt ctgcgccaga tgtaccgtcc tttccaatac   2580

gattttctgt tgcaccttgt agtggattct gcatatcatc tttcccacct aaaaatgtct   2640

gaatgcttac acaaataaat tttataacac gcttattttg c                       2681


<210>  8395
<211>  431
<212>  PRT
<213>  Homo sapiens

<400>  8395

Met Ala His Ser Pro Val Gln Ser Gly Leu Pro Gly Met Gln Asn Leu 
1               5                   10                  15


Lys Ala Asp Pro Glu Glu Leu Phe Thr Lys Leu Glu Lys Ile Gly Lys 
            20                  25                  30


Gly Ser Phe Gly Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Lys 
        35                  40                  45


Val Val Ala Ile Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile 
    50                  55                  60


Glu Asp Ile Gln Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Pro 
65                  70                  75                  80


Tyr Val Thr Lys Tyr Tyr Gly Ser Tyr Leu Lys Asp Thr Lys Leu Trp 
                85                  90                  95


Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Glu 
            100                 105                 110


Pro Gly Pro Leu Asp Glu Thr Gln Ile Ala Thr Ile Leu Arg Glu Ile 
        115                 120                 125


Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp 
    130                 135                 140


Ile Lys Ala Ala Asn Val Leu Leu Ser Glu His Gly Glu Val Lys Leu 
145                 150                 155                 160


Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg 
                165                 170                 175


Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Lys 
            180                 185                 190


Gln Ser Ala Tyr Asp Ser Lys Ala Asp Ile Trp Ser Leu Gly Ile Thr 
        195                 200                 205


Ala Ile Glu Leu Ala Arg Gly Glu Pro Pro His Ser Glu Leu His Pro 
    210                 215                 220


Met Lys Val Leu Phe Leu Ile Pro Lys Asn Asn Pro Pro Thr Leu Glu 
225                 230                 235                 240


Gly Asn Tyr Ser Lys Pro Leu Lys Glu Phe Val Glu Ala Cys Leu Asn 
                245                 250                 255


Lys Glu Pro Ser Phe Arg Pro Thr Ala Lys Glu Leu Leu Lys His Lys 
            260                 265                 270


Phe Ile Leu Arg Asn Ala Lys Lys Thr Ser Tyr Leu Thr Glu Leu Ile 
        275                 280                 285


Asp Arg Tyr Lys Arg Trp Lys Ala Glu Gln Ser His Asp Asp Ser Ser 
    290                 295                 300


Ser Glu Asp Ser Asp Ala Glu Thr Asp Gly Gln Ala Ser Gly Gly Ser 
305                 310                 315                 320


Asp Ser Gly Asp Trp Ile Phe Thr Ile Arg Glu Lys Asp Pro Lys Asn 
                325                 330                 335


Leu Glu Asn Gly Ala Leu Gln Pro Ser Asp Leu Asp Arg Asn Lys Met 
            340                 345                 350


Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile Ile 
        355                 360                 365


Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly Gly 
    370                 375                 380


Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala Glu 
385                 390                 395                 400


Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val Gln 
                405                 410                 415


Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
            420                 425                 430


<210>  8396
<211>  866
<212>  DNA
<213>  Homo sapiens

<400>  8396
tttggcgtgg ctggccagct gacagacacc cagatcaaaa ggaacacctt cccatcggac     60

ttggacagaa ataagatgaa agacatcccg aagaggcctt tctctcagtg tttatctaca    120

attatttctc ctctgtttgc agagttgaag gagaagagcc aggcgtgcgg agggaacttg    180

gggtccattg aagagctgcg aggggccatc tacctagcgg aggaggcgtg ccctggcatc    240

tccgacacca tggtggccca gctcgtgcag cggctccaga gatactctct aagtggtgga    300

ggaacttcat cccactgaaa ttcctttggc atttggggtt ttgtttttcc ttttttcctt    360

cttcatcctc ctcctttttt aaaagtcaac gagagccttc gctgactcca ccgaagaggt    420

gcgccactgg gagccacccc agcgccaggc gcccgtccag ggacacacac agtcttcact    480

gtgctgcagc cagatgaagt ctctcagatg ggtggggagg gtcagctcct tccagcgatc    540

attttatttt attttattac ttttgttttt aattttaacc atagtgcaca tattccagga    600

aagtgtcttt aaaaacaaaa acaaaccctg aaatgtatat ttgggattat gataaggcaa    660

ctaaagacat gaaacctcag gtatcctgct ttaagttgat aactccctct gggagctgga    720

gaatcgctct ggtggatggg tgtacagatt tgtatataat gtcattttta cggaaaccct    780

ttcggcgtgc ataaggaatc actgtgtaca aactggccaa gtgcttctgt agataacgtc    840

agtggagtaa atattcgaca ggccat                                         866


<210>  8397
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  8397

Met Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile 
1               5                   10                  15


Ile Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly 
            20                  25                  30


Gly Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala 
        35                  40                  45


Glu Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val 
    50                  55                  60


Gln Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
65                  70                  75                  80


<210>  8398
<211>  2209
<212>  DNA
<213>  Homo sapiens

<400>  8398
gggacgcgct cggcgctcgc gggctcggcg ggctgtgcgc gcccactccg gctccagcgg     60

ccagcgcgcg cgggcccagg ccgcccggct ccagcccagc agtagcggca gcagcggcgg    120

cggcggcagt gcgcgcgagg ccctgcgccc ccagcagctc ctccctggcg ccgtgcatgg    180

agacgcggcc cgccacccgc cgctgagccc ccgccgcccg gccgggaccc gccagggctg    240

gggtggcctc gggctccggc cggccccgcc gcccgagggc tgcgcgcggc ccgcgggcct    300

cgccgccccg cgcggatcgt cgcggcccgg ccgtcccgtc ccaggaagtg gccgtcctga    360

gcgccatggc tcactccccg gtgcagtcgg gcctgcccgg catgcagaac ctaaaggcag    420

acccagaaga gctttttaca aaactagaga aaattgggaa gggctccttt ggagaggtgt    480

tcaaaggcat tgacaatcgg actcagaaag tggttgccat aaagatcatt gatctggaag    540

aagctgaaga tgagatagag gacattcaac aagaaatcac agtgctgagt cagtgtgaca    600

gtccatatgt aaccaaatat tatggatcct atctgaagga tacaaaatta tggataataa    660

tggaatatct tggtggaggc tccgcactag atctattaga acctggccca ttagatgaaa    720

cccagatcgc tactatatta agagaaatac tgaaaggact cgattatctc cattcggaga    780

agaaaatcca cagagacatt aaagcggcca acgtcctgct gtctgagcat ggcgaggtga    840

agctggcgga ctttggcgtg gctggccagc tgacagacac ccagatcaaa aggaacacct    900

tcgtgggcac cccattctgg atggcacccg aggtcatcaa acagtcggcc tatgactcga    960

aggcagacat ctggtccctg ggcataacag ctattgaact tgcaagaggg gaaccacctc   1020

attccgagct gcaccccatg aaagttttat tcctcattcc aaagaacaac ccaccgacgt   1080

tggaaggaaa ctacagtaaa cccctcaagg agtttgtgga ggcctgtttg aataaggagc   1140

cgagctttag acccactgct aaggagttat tgaagcacaa gtttatacta cgcaatgcaa   1200

agaaaacttc ctacttgacc gagctcatcg acaggtacaa gagatggaag gccgagcaga   1260

gccatgacga ctcgagctcc gaggattccg acgcggaaac agatggccaa gcctcggggg   1320

gcagtgattc tggggactgg atcttcacaa tccgagaaaa agatcccaag aatctcgaga   1380

atggagctct tcagccatcg gacttggaca gaaataagat gaaagacatc ccgaagaggc   1440

ctttctctca gtgtttatct acaattattt ctcctctgtt tgcagagttg aaggagaaga   1500

gccaggcgtg cggagggaac ttggggtcca ttgaagagct gcgaggggcc atctacctag   1560

cggaggaggc gtgccctggc atctccgaca ccatggtggc ccagctcgtg cagcggctcc   1620

agagatactc tctaagtggt ggaggaactt catcccactg aaattccttt ggcatttggg   1680

gttttgtttt tccttttttc cttcttcatc ctcctccttt tttaaaagtc aacgagagcc   1740

ttcgctgact ccaccgaaga ggtgcgccac tgggagccac cccagcgcca ggcgcccgtc   1800

cagggacaca cacagtcttc actgtgctgc agccagatga agtctctcag atgggtgggg   1860

agggtcagct ccttccagcg atcattttat tttattttat tacttttgtt tttaatttta   1920

accatagtgc acatattcca ggaaagtgtc tttaaaaaca aaaacaaacc ctgaaatgta   1980

tatttgggat tatgataagg caactaaaga catgaaacct caggtatcct gctttaagtt   2040

gataactccc tctgggagct ggagaatcgc tctggtggat gggtgtacag atttgtatat   2100

aatgtcattt ttacggaaac cctttcggcg tgcataagga atcactgtgt acaaactggc   2160

caagtgcttc tgtagataac gtcagtggag taaatattcg acaggccat               2209


<210>  8399
<211>  431
<212>  PRT
<213>  Homo sapiens

<400>  8399

Met Ala His Ser Pro Val Gln Ser Gly Leu Pro Gly Met Gln Asn Leu 
1               5                   10                  15


Lys Ala Asp Pro Glu Glu Leu Phe Thr Lys Leu Glu Lys Ile Gly Lys 
            20                  25                  30


Gly Ser Phe Gly Glu Val Phe Lys Gly Ile Asp Asn Arg Thr Gln Lys 
        35                  40                  45


Val Val Ala Ile Lys Ile Ile Asp Leu Glu Glu Ala Glu Asp Glu Ile 
    50                  55                  60


Glu Asp Ile Gln Gln Glu Ile Thr Val Leu Ser Gln Cys Asp Ser Pro 
65                  70                  75                  80


Tyr Val Thr Lys Tyr Tyr Gly Ser Tyr Leu Lys Asp Thr Lys Leu Trp 
                85                  90                  95


Ile Ile Met Glu Tyr Leu Gly Gly Gly Ser Ala Leu Asp Leu Leu Glu 
            100                 105                 110


Pro Gly Pro Leu Asp Glu Thr Gln Ile Ala Thr Ile Leu Arg Glu Ile 
        115                 120                 125


Leu Lys Gly Leu Asp Tyr Leu His Ser Glu Lys Lys Ile His Arg Asp 
    130                 135                 140


Ile Lys Ala Ala Asn Val Leu Leu Ser Glu His Gly Glu Val Lys Leu 
145                 150                 155                 160


Ala Asp Phe Gly Val Ala Gly Gln Leu Thr Asp Thr Gln Ile Lys Arg 
                165                 170                 175


Asn Thr Phe Val Gly Thr Pro Phe Trp Met Ala Pro Glu Val Ile Lys 
            180                 185                 190


Gln Ser Ala Tyr Asp Ser Lys Ala Asp Ile Trp Ser Leu Gly Ile Thr 
        195                 200                 205


Ala Ile Glu Leu Ala Arg Gly Glu Pro Pro His Ser Glu Leu His Pro 
    210                 215                 220


Met Lys Val Leu Phe Leu Ile Pro Lys Asn Asn Pro Pro Thr Leu Glu 
225                 230                 235                 240


Gly Asn Tyr Ser Lys Pro Leu Lys Glu Phe Val Glu Ala Cys Leu Asn 
                245                 250                 255


Lys Glu Pro Ser Phe Arg Pro Thr Ala Lys Glu Leu Leu Lys His Lys 
            260                 265                 270


Phe Ile Leu Arg Asn Ala Lys Lys Thr Ser Tyr Leu Thr Glu Leu Ile 
        275                 280                 285


Asp Arg Tyr Lys Arg Trp Lys Ala Glu Gln Ser His Asp Asp Ser Ser 
    290                 295                 300


Ser Glu Asp Ser Asp Ala Glu Thr Asp Gly Gln Ala Ser Gly Gly Ser 
305                 310                 315                 320


Asp Ser Gly Asp Trp Ile Phe Thr Ile Arg Glu Lys Asp Pro Lys Asn 
                325                 330                 335


Leu Glu Asn Gly Ala Leu Gln Pro Ser Asp Leu Asp Arg Asn Lys Met 
            340                 345                 350


Lys Asp Ile Pro Lys Arg Pro Phe Ser Gln Cys Leu Ser Thr Ile Ile 
        355                 360                 365


Ser Pro Leu Phe Ala Glu Leu Lys Glu Lys Ser Gln Ala Cys Gly Gly 
    370                 375                 380


Asn Leu Gly Ser Ile Glu Glu Leu Arg Gly Ala Ile Tyr Leu Ala Glu 
385                 390                 395                 400


Glu Ala Cys Pro Gly Ile Ser Asp Thr Met Val Ala Gln Leu Val Gln 
                405                 410                 415


Arg Leu Gln Arg Tyr Ser Leu Ser Gly Gly Gly Thr Ser Ser His 
            420                 425                 430


<210>  8400
<211>  421
<212>  DNA
<213>  Homo sapiens

<400>  8400
gaatctgtag tactgtcact gcaaccatac gctctagaaa tatattgctt tagagaaaaa     60

gcagcaaggc caaataaatt gatacagaag aaatgtttag atatgttttt gcaagtttct    120

gcatatctga aatagaacca atacatcaca tggaaagcca atggctgtgt tttgagttta    180

tggagagcca tatgtggcaa ggaactgagg gtggcatcca ggcaacagac ttcaagaaac    240

tgaggctgtc agtccaacaa cccacaagaa ctgaatctga ccaacaatca caggaacaaa    300

cttagaagta tactctttcc cagacaaacc ttcagatgag accacagccc cagccataag    360

cttgaaaaca atctcatgag ggaccttgag ccacaggcat gtagtaaagc tatgccagga    420

a                                                                    421


<210>  8401
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8401

Met Phe Arg Tyr Val Phe Ala Ser Phe Cys Ile Ser Glu Ile Glu Pro 
1               5                   10                  15


Ile His His Met Glu Ser Gln Trp Leu Cys Phe Glu Phe Met Glu Ser 
            20                  25                  30


His Met Trp Gln Gly Thr Glu Gly Gly Ile Gln Ala Thr Asp Phe Lys 
        35                  40                  45


Lys Leu Arg Leu Ser Val Gln Gln Pro Thr Arg Thr Glu Ser Asp Gln 
    50                  55                  60


Gln Ser Gln Glu Gln Thr 
65                  70


<210>  8402
<211>  771
<212>  DNA
<213>  Homo sapiens

<400>  8402
ggtttgtcac agatacacta atcatataaa tgtaactcat acatttacaa ggctatacat     60

cacactgcag actgaaatct aaatttaaag aaataaactg gagcttgggg attctgcttt    120

tgcatcttcc tcgttttctc ttgccgctgc caagtaagaa gtgcctttca cctcacacca    180

tgtttctgag gcctccccag ccatgtggaa ctgcaagtcc agttaaacct ctttttcttc    240

tcaggttcca aaattatttt aggcatggga tcaaagaaga aacttctttg tagcagcatc    300

ccagtactag gactttttgt ctctgcatgg aaatctgaat atatttatat gttggagtga    360

catctctaca ggaagcctag agacctaact gtttgctaca tgtcaccaaa gttaaagtgg    420

ctaccttaat gagcagccag gatgccatca tctccgacct gaatgacaat aacctccaaa    480

ccagcctttg tatactcctt cctgctgctc tgcagtccac ttccacagac cagccaactg    540

aatctcctta tagattcata atggccatca gcacaaagat gttttatctg cagtcaacca    600

gtcatgtttc atgatggcat caaaatgtgt gctggagttt gctgggggtc cactctagat    660

cctgtttgcc tgagtatcac cagcggacac tgtagaacag caaagattgc tgcctgctcc    720

ttcctctgga agcttcgtcc cagaggggca cctgcaagat gccaaccaga g             771


<210>  8403
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  8403

Met Ser Ser Gln Asp Ala Ile Ile Ser Asp Leu Asn Asp Asn Asn Leu 
1               5                   10                  15


Gln Thr Ser Leu Cys Ile Leu Leu Pro Ala Ala Leu Gln Ser Thr Ser 
            20                  25                  30


Thr Asp Gln Pro Thr Glu Ser Pro Tyr Arg Phe Ile Met Ala Ile Ser 
        35                  40                  45


Thr Lys Met Phe Tyr Leu Gln Ser Thr Ser His Val Ser 
    50                  55                  60


<210>  8404
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  8404
gagtgaaccc acaaaaacaa gagaacatca tgtttctaga ggctgcctgc attccttggc     60

taatgacttt gcatcactct gacgtcttgc tcccatggtc gtatcaccta ctactggccc    120

tgatctcact acttgttata tggaacaaag ggataaggaa gtgacttgcc taagtcactg    180

aggaacctaa tattgagatt agcactcaat gattcctggc tctcagaatg tgtgctgcta    240

ccaccaggcc acactcttcc ctccagagag aagatgtgtc agcacggaat tgtgctgaag    300

caaagatgtg aaatagaatg attacatatc tacctagtgg gaagatctgg ggaagaatct    360

atcagtgctg gcagagaagc aaaccatacg acatcactca tccccagaaa gtgaagttaa    420

gggaaataaa aaacaatcta caccatttag aaaacacagc caccccatac ccttggaaaa    480

aatacactaa aatatcttca tctgatttga cctctaataa catgaataat tgtcttataa    540


<210>  8405
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  8405

Met Phe Leu Glu Ala Ala Cys Ile Pro Trp Leu Met Thr Leu His His 
1               5                   10                  15


Ser Asp Val Leu Leu Pro Trp Ser Tyr His Leu Leu Leu Ala Leu Ile 
            20                  25                  30


Ser Leu Leu Val Ile Trp Asn Lys Gly Ile Arg Lys 
        35                  40


<210>  8406
<211>  717
<212>  DNA
<213>  Homo sapiens

<400>  8406
aaggctgcaa acgaagccag aaagatggtg gccagcacac ctatggcaac tatcaccacg     60

gtctccatgc ttccggggag ctcctgactc agtcccgttc acatcgtcct catgggctaa    120

ggctgctgga agtggcaaac tgggggaaga ggatggcagg agctaggttc ctccacgaca    180

cctccagaga cctgagggcc tcaagctgca gctccggggc acatcccgct gcgctcccac    240

gacggccccg cggatggcaa agtcagcggc atcgcctatg caggcaatca aaggatgttg    300

atggataagt gtttcaggca gaataatggc cctcaaagat gttgacacca gaatcttcag    360

aacctttgca tatgttacct aacatgacaa aagggacttt gctgatgtga ttaaggttaa    420

gaactttgag aagggaagat tatcctggat tatacaggtc gacgtttatt tctttctgaa    480

ctttcctgga ggatcatcgg ccatactcca gcagaagggt ggatttgaaa aaataacgtt    540

tccacggcaa cagtggcagc aattcaaagg aagacgttgg agaattcaca tgctatttta    600

gctggctctg tgattgcaat cacacaaatc attacattcc agcgagatcc catcaacaga    660

aggtttttcc atttcagtct gtcaagtgaa atgaaaagga gcttttgaaa aacgtct       717


<210>  8407
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  8407

Met Ala Gly Ala Arg Phe Leu His Asp Thr Ser Arg Asp Leu Arg Ala 
1               5                   10                  15


Ser Ser Cys Ser Ser Gly Ala His Pro Ala Ala Leu Pro Arg Arg Pro 
            20                  25                  30


Arg Gly Trp Gln Ser Gln Arg His Arg Leu Cys Arg Gln Ser Lys Asp 
        35                  40                  45


Val Asp Gly 
    50


<210>  8408
<211>  548
<212>  DNA
<213>  Homo sapiens

<400>  8408
tcaagctgca gctccggggc acatcccgct gcgctcccac gacggccccg cggatggcaa     60

agtcagcggc atcgcctatg caggcaatca aaggatgttg atggataagt gtttcaggca    120

gaataatggc cctcaaagat gttgacacca gaatcttcag aacctttgca tatgttacct    180

aacatgacaa aagggacttt gctgatgtga ttaaggttaa gaactttgag aagggaagat    240

tatcctggat tatacaggtc gacgtttatt tctttctgaa ctttcctgga ggatcatcgg    300

ccatactcca gcagaagggt ggatttgaaa aaataacgtt tccacggcaa cagtggcagc    360

aattcaaagg aagacgttgg agaattcaca tgctatttta gctggctctg tgattgcaat    420

cacacaaatc attacattcc agcgagatcc catcaacaga aggtttttcc atttcagtct    480

gtcaagtttt tcaggcatga atactgtaag caagaagaga aaagttacaa taaattgaca    540

tttatagt                                                             548


<210>  8409
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  8409

Arg Phe His Gly Asn Ser Gly Ser Asn Ser Lys Glu Asp Val Gly Glu 
1               5                   10                  15


Phe Thr Cys Tyr Phe Ser Trp Leu Cys Asp Cys Asn His Thr Asn His 
            20                  25                  30


Tyr Ile Pro Ala Arg Ser His Gln Gln Lys Val Phe Pro Phe Gln Ser 
        35                  40                  45


Val Lys Phe Phe Arg His Glu Tyr Cys Lys Gln Glu Glu Lys Ser Tyr 
    50                  55                  60


Asn Lys Leu Thr Phe 
65


<210>  8410
<211>  1864
<212>  DNA
<213>  Homo sapiens

<400>  8410
ctgccctctg ggtctgttac agtccaactt ggtggcaagg acagagggcc tggaccagca     60

ggtggactgg aactggtaag aaaagagctt gggtgctcca gagatagccc caccataaag    120

acagtgggtt tcagggtccc tgtcaaggaa tggaacggct cctgacccca aagtccagat    180

gtttggctgg tcagtcgggt gcaagtttat gcccttggga acagagtttt gcctcactct    240

gtgagggctg taggcctatg gtcgaaaggg aaggggcttc tgtctcctgg ggctcacctc    300

tgtgcagaga aacctcttcc tacccagacc attctaggta aaagccaagc tatattcttc    360

ctcctctagc agtcctctct cctacctttc ctcaggtatg atgttctgtc cccgggggag    420

atgcaacggc tctcctttgc ccgactcttc tacctgcagc cgaagtacgc agtgcttgat    480

gaagccacca gtgccctgac agaggaagtg gagagcgagc tctatcgcat cggccagcag    540

ctggggatga cgttcatcag tgtgggacat cggcagagcc ttgagaaggt acccgtgctc    600

acaaggatgg cctgaggagg agaaagaacc caaaggctca gcctggccag ggccagaggc    660

ccctcaaaac ggggagtagc agtagcagag agaaccgagt ggcctcctct gccagcggcc    720

agggcagcct gatctccatg tggtggtggt ctcttgtagt ttcattcctt ggttctgaaa    780

ctctgtggag gaggaagatg ggagctgatg agaatcaaag tggaatgaag ctctggcttt    840

tggaaggaga gccacactgt ggcgggtcgg cggccctcag gagagaccag gaggactgac    900

agcgaagatc gagctcaggt tcgccacata gatcccgtgc aggagccaca tgggtcctgt    960

gcaggacccc tagcagtggt gggctgagcc caggtctagg tttctgtggg ggacactgaa   1020

tctcccagtg ttcagtctcc caggactctg ctgcctcagc cagagcctcc atatgcttga   1080

agtgctgatt acctacaaat gatttcagat catgtttgct aaagagaaat ctggaagtgt   1140

gagatctgta agaaatgaaa gaaatgactc ttggagtcaa gagatctgga aatcttttaa   1200

tcagttaaat tgtgcagcaa tagattttta actttaactg accatttaag ttttttaata   1260

agttttttac aaagaaaagt taaacattaa aaagaattac agctttctgt cttctctatc   1320

atggaatgat cttttttatt gaatctccag atttgtattt gacagcttgg tgggaaggga   1380

agcacactct gctgttctgg aatcttatgc ccagggtttt tcacttctcc ccacatctcc   1440

ctttccactt gccagtgttg tgtagttaga acctgaacca ctaacttcca ggggcctttg   1500

gtctgcccta ccttaaccca aatgaaagta aatccctttc cccttagcca aaataaggtt   1560

gggttttcta aaaaaatagt ctatattagg gaacaacaac agcaaattag acaaaaccca   1620

gaaagcacaa agcatgaggt ggagttactg tgcccaaagt cctcactcag accagtgccc   1680

ctccagttca gttgtctatg tattaccttc cttaccttca taatttttgc caggcttctg   1740

tacttctagt acttgagtta cttaatattt ttaaaaacaa accttttaag tttaaatgga   1800

tttttaagtg aaattttaca cttaacatag atggaaagta actaaaaata aatacaagaa   1860

aaac                                                                1864


<210>  8411
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8411

Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
1               5                   10                  15


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
            20                  25                  30


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
        35                  40                  45


Gly His Arg Gln Ser Leu Glu Lys Val Pro Val Leu Thr Arg Met Ala 
    50                  55                  60


<210>  8412
<211>  1592
<212>  DNA
<213>  Homo sapiens

<400>  8412
ggatctgagc ctaaagatct ccgagggaca gagcctgctc atcacaggca acacgggcac     60

tggctcagtg cagatgctga cggactttgg gccccatggg gtgctattcc tgccacaaaa    120

gccattcttc actgacggga cccttcggga gcaggtgata tatcccctga aggaggtcta    180

ccccgactca ggttctgccg atgatgagag gatcttgagg ttcttggaat tggcaggcct    240

gtccaacttg gtggcaagga cagagggcct ggaccagcag gtggactgga actggtatga    300

tgttctgtcc ccgggggaga tgcaacggct ctcctttgcc cgactcttct acctgcagcc    360

gaagtacgca gtgcttgatg aagccaccag tgccctgaca gaggaagtgg agagcgagct    420

ctatcgcatc ggccagcagc tggggatgac gttcatcagt gtgggacatc ggcagagcct    480

tgagaagttt cattccttgg ttctgaaact ctgtggagga ggaagatggg agctgatgag    540

aatcaaagtg gaatgaagct ctggcttttg gaaggagagc cacactgtgg cgggtcggcg    600

gccctcagga gagaccagga ggactgacag cgaagatcga gctcaggttc gccacataga    660

tcccgtgcag gagccacatg ggtcctgtgc aggaccccta gcagtggtgg gctgagccca    720

ggtctaggtt tctgtggggg acactgaatc tcccagtgtt cagtctccca ggactctgct    780

gcctcagcca gagcctccat atgcttgaag tgctgattac ctacaaatga tttcagatca    840

tgtttgctaa agagaaatct ggaagtgtga gatctgtaag aaatgaaaga aatgactctt    900

ggagtcaaga gatctggaaa tcttttaatc agttaaattg tgcagcaata gatttttaac    960

tttaactgac catttaagtt ttttaataag ttttttacaa agaaaagtta aacattaaaa   1020

agaattacag ctttctgtct tctctatcat ggaatgatct tttttattga atctccagat   1080

ttgtatttga cagcttggtg ggaagggaag cacactctgc tgttctggaa tcttatgccc   1140

agggtttttc acttctcccc acatctccct ttccacttgc cagtgttgtg tagttagaac   1200

ctgaaccact aacttccagg ggcctttggt ctgccctacc ttaacccaaa tgaaagtaaa   1260

tccctttccc cttagccaaa ataaggttgg gttttctaaa aaaatagtct atattaggga   1320

acaacaacag caaattagac aaaacccaga aagcacaaag catgaggtgg agttactgtg   1380

cccaaagtcc tcactcagac cagtgcccct ccagttcagt tgtctatgta ttaccttcct   1440

taccttcata atttttgcca ggcttctgta cttctagtac ttgagttact taatattttt   1500

aaaaacaaac cttttaagtt taaatggatt tttaagtgaa attttacact taacatagat   1560

ggaaagtaac taaaaataaa tacaagaaaa ac                                 1592


<210>  8413
<211>  160
<212>  PRT
<213>  Homo sapiens

<400>  8413

Met Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys 
1               5                   10                  15


Pro Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu 
            20                  25                  30


Lys Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu 
        35                  40                  45


Arg Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu 
    50                  55                  60


Gly Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro 
65                  70                  75                  80


Gly Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro 
                85                  90                  95


Lys Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val 
            100                 105                 110


Glu Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile 
        115                 120                 125


Ser Val Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu 
    130                 135                 140


Lys Leu Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
145                 150                 155                 160


<210>  8414
<211>  1444
<212>  DNA
<213>  Homo sapiens

<400>  8414
tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc agtgcttgat     60

gaagccacca gtgccctgac agaggaagtg gagagcgagc tctatcgcat cggccagcag    120

ctggggatga cgttcatcag tgtgggacat cggcagagcc ttgagaaggt acccgtgctc    180

acaaggatgg cctgaggagg agaaagaacc caaaggctca gcctggccag ggccagaggc    240

ccctcaaaac ggggagtagc agtagcagag agaaccgagt ggcctcctct gccagcggcc    300

agggcagcct gatctccatg tggtggtggt ctcttgtagt ttcattcctt ggttctgaaa    360

ctctgtggag gaggaagatg ggagctgatg agaatcaaag tggaatgaag ctctggcttt    420

tggaaggaga gccacactgt ggcgggtcgg cggccctcag gagagaccag gaggactgac    480

agcgaagatc gagctcaggt tcgccacata gatcccgtgc aggagccaca tgggtcctgt    540

gcaggacccc tagcagtggt gggctgagcc caggtctagg tttctgtggg ggacactgaa    600

tctcccagtg ttcagtctcc caggactctg ctgcctcagc cagagcctcc atatgcttga    660

agtgctgatt acctacaaat gatttcagat catgtttgct aaagagaaat ctggaagtgt    720

gagatctgta agaaatgaaa gaaatgactc ttggagtcaa gagatctgga aatcttttaa    780

tcagttaaat tgtgcagcaa tagattttta actttaactg accatttaag ttttttaata    840

agttttttac aaagaaaagt taaacattaa aaagaattac agctttctgt cttctctatc    900

atggaatgat cttttttatt gaatctccag atttgtattt gacagcttgg tgggaaggga    960

agcacactct gctgttctgg aatcttatgc ccagggtttt tcacttctcc ccacatctcc   1020

ctttccactt gccagtgttg tgtagttaga acctgaacca ctaacttcca ggggcctttg   1080

gtctgcccta ccttaaccca aatgaaagta aatccctttc cccttagcca aaataaggtt   1140

gggttttcta aaaaaatagt ctatattagg gaacaacaac agcaaattag acaaaaccca   1200

gaaagcacaa agcatgaggt ggagttactg tgcccaaagt cctcactcag accagtgccc   1260

ctccagttca gttgtctatg tattaccttc cttaccttca taatttttgc caggcttctg   1320

tacttctagt acttgagtta cttaatattt ttaaaaacaa accttttaag tttaaatgga   1380

tttttaagtg aaattttaca cttaacatag atggaaagta actaaaaata aatacaagaa   1440

aaac                                                                1444


<210>  8415
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  8415

Met Lys Val Asn Pro Phe Pro Leu Ser Gln Asn Lys Val Gly Phe Ser 
1               5                   10                  15


Lys Lys Ile Val Tyr Ile Arg Glu Gln Gln Gln Gln Ile Arg Gln Asn 
            20                  25                  30


Pro Glu Ser Thr Lys His Glu Val Glu Leu Leu Cys Pro Lys Ser Ser 
        35                  40                  45


Leu Arg Pro Val Pro Leu Gln Phe Ser Cys Leu Cys Ile Thr Phe Leu 
    50                  55                  60


Thr Phe Ile Ile Phe Ala Arg Leu Leu Tyr Phe 
65                  70                  75


<210>  8416
<211>  3043
<212>  DNA
<213>  Homo sapiens

<400>  8416
gcttccggga gagtccgcgt ctcccgcacc ttcctctcta tcaaacgccg tctctgtggt     60

agccggggcc ccgcccctcc tcggactcta cccagtactg aactaggggc agctgggctc    120

cagagtccct cgggtctcag gtcatggcgg tcgcggggcc cgcgcccgga gctggcgcca    180

ggcccaggtt agatctgcaa tttctccagc ggttcctgca gatactgaag gttttgtttc    240

cttcttggtc atcacaaaat gccttgatgt tcctgaccct tttgtgcctg accctactgg    300

ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc    360

actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg    420

cgggatgaca tcgataaccc ggaccagcgc atcagccagg acgtggagcg attctgccgg    480

cagctcagca gcatggccag caagctcatc atctccccgt tcaccctcgt ctactacact    540

taccagtgct tccaaagcac aggctggctc gggcctgtga gcatcttcgg gtatttcatc    600

ctggggaccg tggtgaacaa aactttgatg ggccccattg tgatgaagct ggtgcatcag    660

gagaagctgg agggagattt taggttcaag cacatgcaga ttcgggtgaa tgcggagcct    720

gctgctttct acagagctgg gcatgtggag cacatgagga cagaccgcag gctgcagaga    780

ctccttcaga cccagaggga gctgatgtcc aaggagctct ggctgtacat cggcatcaac    840

acctttgact atctgggcag catcctgagt tacgttgtca tcgcaatccc cattttcagc    900

ggggtctatg gagacctgag tcccgcagag cttagcaccc tggtcagcaa gaatgccttt    960

gtgtgcatct acctcatcag ctgcttcacc cagctcatcg acctgtccac gacgctctca   1020

gatgtggctg gctacacgca cagaattggg cagcttcggg agacgcttct ggacatgtcc   1080

ctgaagtcac aggactgcga gatcctgggc gagagcgagt ggggcttgga cacaccccca   1140

gggtggccag cggcagagcc agcagacaca gcatttctcc ttgagcgggt ctccatctct   1200

gccccctcct ctgacaaacc cctaatcaag gatctgagcc taaagatctc cgagggacag   1260

agcctgctca tcacaggcaa cacgggcact ggcaagacct ccttgctccg ggttctgggt   1320

ggcctctgga cgagtacacg gggctcagtg cagatgctga cggactttgg gccccatggg   1380

gtgctattcc tgccacaaaa gccattcttc actgacggga cccttcggga gcaggtgata   1440

tatcccctga aggaggtcta ccccgactca ggttctgccg atgatgagag gatcttgagg   1500

ttcttggaat tggcaggcct gtccaacttg gtggcaagga cagagggcct ggaccagcag   1560

gtggactgga actggtatga tgttctgtcc ccgggggaga tgcaacggct ctcctttgcc   1620

cgactcttct acctgcagcc gaagtacgca gtgcttgatg aagccaccag tgccctgaca   1680

gaggaagtgg agagcgagct ctatcgcatc ggccagcagc tggggatgac gttcatcagt   1740

gtgggacatc ggcagagcct tgagaaggta cccgtgctca caaggatggc ctgaggagga   1800

gaaagaaccc aaaggctcag cctggccagg gccagaggcc cctcaaaacg gggagtagca   1860

gtagcagaga gaaccgagtg gcctcctctg ccagcggcca gggcagcctg atctccatgt   1920

ggtggtggtc tcttgtagtt tcattccttg gttctgaaac tctgtggagg aggaagatgg   1980

gagctgatga gaatcaaagt ggaatgaagc tctggctttt ggaaggagag ccacactgtg   2040

gcgggtcggc ggccctcagg agagaccagg aggactgaca gcgaagatcg agctcaggtt   2100

cgccacatag atcccgtgca ggagccacat gggtcctgtg caggacccct agcagtggtg   2160

ggctgagccc aggtctaggt ttctgtgggg gacactgaat ctcccagtgt tcagtctccc   2220

aggactctgc tgcctcagcc agagcctcca tatgcttgaa gtgctgatta cctacaaatg   2280

atttcagatc atgtttgcta aagagaaatc tggaagtgtg agatctgtaa gaaatgaaag   2340

aaatgactct tggagtcaag agatctggaa atcttttaat cagttaaatt gtgcagcaat   2400

agatttttaa ctttaactga ccatttaagt tttttaataa gttttttaca aagaaaagtt   2460

aaacattaaa aagaattaca gctttctgtc ttctctatca tggaatgatc ttttttattg   2520

aatctccaga tttgtatttg acagcttggt gggaagggaa gcacactctg ctgttctgga   2580

atcttatgcc cagggttttt cacttctccc cacatctccc tttccacttg ccagtgttgt   2640

gtagttagaa cctgaaccac taacttccag gggcctttgg tctgccctac cttaacccaa   2700

atgaaagtaa atccctttcc ccttagccaa aataaggttg ggttttctaa aaaaatagtc   2760

tatattaggg aacaacaaca gcaaattaga caaaacccag aaagcacaaa gcatgaggtg   2820

gagttactgt gcccaaagtc ctcactcaga ccagtgcccc tccagttcag ttgtctatgt   2880

attaccttcc ttaccttcat aatttttgcc aggcttctgt acttctagta cttgagttac   2940

ttaatatttt taaaaacaaa ccttttaagt ttaaatggat ttttaagtga aattttacac   3000

ttaacataga tggaaagtaa ctaaaaataa atacaagaaa aac                     3043


<210>  8417
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  8417

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg 
                85                  90                  95


Leu Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr 
            100                 105                 110


Ile Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val 
        115                 120                 125


Val Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro 
    130                 135                 140


Ala Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr 
145                 150                 155                 160


Leu Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser 
                165                 170                 175


Asp Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu 
            180                 185                 190


Leu Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser 
        195                 200                 205


Glu Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala 
    210                 215                 220


Asp Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser 
225                 230                 235                 240


Asp Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln 
                245                 250                 255


Ser Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu 
            260                 265                 270


Arg Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met 
        275                 280                 285


Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro 
    290                 295                 300


Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys 
305                 310                 315                 320


Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg 
                325                 330                 335


Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly 
            340                 345                 350


Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly 
        355                 360                 365


Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys 
    370                 375                 380


Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu 
385                 390                 395                 400


Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser 
                405                 410                 415


Val Gly His Arg Gln Ser Leu Glu Lys Val Pro Val Leu Thr Arg Met 
            420                 425                 430


Ala 



<210>  8418
<211>  2872
<212>  DNA
<213>  Homo sapiens

<400>  8418
gcttccggga gagtccgcgt ctcccgcacc ttcctctcta tcaaacgccg tctctgtggt     60

agccggggcc ccgcccctcc tcggactcta cccagtactg aactaggggc agctgggctc    120

cagagtccct cgggtctcag gtcatggcgg tcgcggggcc cgcgcccgga gctggcgcca    180

ggcccaggtt agatctgcaa tttctccagc ggttcctgca gatactgaag gttttgtttc    240

cttcttggtc atcacaaaat gccttgatgt tcctgaccct tttgtgcctg accctactgg    300

ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc    360

actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg    420

cgggatgaca tcgataaccc ggaccagcgc atcagccagg acgtggagcg attctgccgg    480

cagctcagca gcatggccag caagctcatc atctccccgt tcaccctcgt ctactacact    540

taccagtgct tccaaagcac aggctggctc gggcctgtga gcatcttcgg gtatttcatc    600

ctggggaccg tggtgaacaa aactttgatg ggccccattg tgatgaagct ggtgcatcag    660

gagaagctgg agggagattt taggttcaag cacatgcaga ttcgggtgaa tgcggagcct    720

gctgctttct acagagctgg gcatgtggag cacatgagga cagaccgcag gctgcagaga    780

ctccttcaga cccagaggga gctgatgtcc aaggagctct ggctgtacat cggcatcaac    840

acctttgact atctgggcag catcctgagt tacgttgtca tcgcaatccc cattttcagc    900

ggggtctatg gagacctgag tcccgcagag cttagcaccc tggtcagcaa gaatgccttt    960

gtgtgcatct acctcatcag ctgcttcacc cagctcatcg acctgtccac gacgctctca   1020

gatgtggctg gctacacgca cagaattggg cagcttcggg agacgcttct ggacatgtcc   1080

ctgaagtcac aggactgcga gatcctgggc gagagcgagt ggggcttgga cacaccccca   1140

gggtggccag cggcagagcc agcagacaca gcatttctcc ttgagcgggt ctccatctct   1200

gccccctcct ctgacaaacc cctaatcaag gatctgagcc taaagatctc cgagggacag   1260

agcctgctca tcacaggcaa cacgggcact ggcaagacct ccttgctccg ggttctgggt   1320

ggcctctgga cgagtacacg gggctcagtg cagatgctga cggactttgg gccccatggg   1380

gtgctattcc tgccacaaaa gccattcttc actgacggga cccttcggga gcaggtgata   1440

tatcccctga aggaggtcta ccccgactca ggttctgccg atgatgagag gatcttgagg   1500

ttcttggaat tggcaggcct gtccaacttg gtggcaagga cagagggcct ggaccagcag   1560

gtggactgga actggtatga tgttctgtcc ccgggggaga tgcaacggct ctcctttgcc   1620

cgactcttct acctgcagcc gaagtacgca gtgcttgatg aagccaccag tgccctgaca   1680

gaggaagtgg agagcgagct ctatcgcatc ggccagcagc tggggatgac gttcatcagt   1740

gtgggacatc ggcagagcct tgagaagttt cattccttgg ttctgaaact ctgtggagga   1800

ggaagatggg agctgatgag aatcaaagtg gaatgaagct ctggcttttg gaaggagagc   1860

cacactgtgg cgggtcggcg gccctcagga gagaccagga ggactgacag cgaagatcga   1920

gctcaggttc gccacataga tcccgtgcag gagccacatg ggtcctgtgc aggaccccta   1980

gcagtggtgg gctgagccca ggtctaggtt tctgtggggg acactgaatc tcccagtgtt   2040

cagtctccca ggactctgct gcctcagcca gagcctccat atgcttgaag tgctgattac   2100

ctacaaatga tttcagatca tgtttgctaa agagaaatct ggaagtgtga gatctgtaag   2160

aaatgaaaga aatgactctt ggagtcaaga gatctggaaa tcttttaatc agttaaattg   2220

tgcagcaata gatttttaac tttaactgac catttaagtt ttttaataag ttttttacaa   2280

agaaaagtta aacattaaaa agaattacag ctttctgtct tctctatcat ggaatgatct   2340

tttttattga atctccagat ttgtatttga cagcttggtg ggaagggaag cacactctgc   2400

tgttctggaa tcttatgccc agggtttttc acttctcccc acatctccct ttccacttgc   2460

cagtgttgtg tagttagaac ctgaaccact aacttccagg ggcctttggt ctgccctacc   2520

ttaacccaaa tgaaagtaaa tccctttccc cttagccaaa ataaggttgg gttttctaaa   2580

aaaatagtct atattaggga acaacaacag caaattagac aaaacccaga aagcacaaag   2640

catgaggtgg agttactgtg cccaaagtcc tcactcagac cagtgcccct ccagttcagt   2700

tgtctatgta ttaccttcct taccttcata atttttgcca ggcttctgta cttctagtac   2760

ttgagttact taatattttt aaaaacaaac cttttaagtt taaatggatt tttaagtgaa   2820

attttacact taacatagat ggaaagtaac taaaaataaa tacaagaaaa ac           2872


<210>  8419
<211>  447
<212>  PRT
<213>  Homo sapiens

<400>  8419

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg 
                85                  90                  95


Leu Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr 
            100                 105                 110


Ile Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val 
        115                 120                 125


Val Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro 
    130                 135                 140


Ala Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr 
145                 150                 155                 160


Leu Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser 
                165                 170                 175


Asp Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu 
            180                 185                 190


Leu Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser 
        195                 200                 205


Glu Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala 
    210                 215                 220


Asp Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser 
225                 230                 235                 240


Asp Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln 
                245                 250                 255


Ser Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu 
            260                 265                 270


Arg Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met 
        275                 280                 285


Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro 
    290                 295                 300


Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys 
305                 310                 315                 320


Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg 
                325                 330                 335


Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly 
            340                 345                 350


Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly 
        355                 360                 365


Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys 
    370                 375                 380


Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu 
385                 390                 395                 400


Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser 
                405                 410                 415


Val Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu Lys 
            420                 425                 430


Leu Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
        435                 440                 445


<210>  8420
<211>  3508
<212>  DNA
<213>  Homo sapiens

<400>  8420
cgcttccggg agagtccgcg tctcccgcac cttcctctct atcaaacgcc gtctctgtgg     60

tagccggggc cccgcccctc ctcggactct acccagtact gaactagggg cagctgggct    120

ccagagtccc tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc    180

aggcccaggt tagatctgca atttctccag cggttcctgc agatactgaa ggttttgttt    240

ccttcttggt catcacaaaa tgccttgatg ttcctgaccc ttttgtgcct gaccctactg    300

gagcaatttg tgatctacca ggttggcttg atccccagtc agtactatgg ggtcctggga    360

aacaaagact tggaagggtt taagactctg acattcctgg ctgtcatgct cattgttctg    420

aactccacgc tgaagagctt tgatcagttc acctgcaacc tgctgtatgt gagctggagg    480

aaggacctca ctgagcacct tcaccgcctc tacttccggg gccgtgcgta ctacaccctc    540

aacgtgctgc gggatgacat cgataacccg gaccagcgca tcagccagga cgtggagcga    600

ttctgccggc agctcagcag catggccagc aagctcatca tctccccgtt caccctcgtc    660

tactacactt accagtgctt ccaaagcaca ggctggctcg ggcctgtgag catcttcggg    720

tatttcatcc tggggaccgt ggtgaacaaa actttgatgg gccccattgt gatgaagctg    780

gtgcatcagg agaagctgga gggagatttt aggttcaagc acatgcagat tcgggtgaat    840

gcggagcctg ctgctttcta cagagctggg catgtggagc acatgaggac agaccgcagg    900

ctgcagagac tccttcagac ccagagggag ctgatgtcca aggagctctg gctgtacatc    960

ggcatcaaca cctttgacta tctgggcagc atcctgagtt acgttgtcat cgcaatcccc   1020

attttcagcg gggtctatgg agacctgagt cccgcagagc ttagcaccct ggtcagcaag   1080

aatgcctttg tgtgcatcta cctcatcagc tgcttcaccc agctcatcga cctgtccacg   1140

acgctctcag atgtggctgg ctacacgcac agaattgggc agcttcggga gacgcttctg   1200

gacatgtccc tgaagtcaca ggactgcgag atcctgggcg agagcgagtg gggcttggac   1260

acacccccag ggtggccagc ggcagagcca gcagacacag catttctcct tgagcgggtc   1320

tccatctctg ccccctcctc tgacaaaccc ctaatcaagg atctgagcct aaagatctcc   1380

gagggacaga gcctgctcat cacaggcaac acgggcactg gcaagacctc cttgctccgg   1440

gttctgggtg gcctctggac gagtacacgg ggctcagtgc agatgctgac ggactttggg   1500

ccccatgggg tgctattcct gccacaaaag ccattcttca ctgacgggac ccttcgggag   1560

caggtcagtc tagttcaggg ggctcactcc tccctcctca accccgccca cccacagctg   1620

ggacctctgg cactgtgaca agtctcaggt cctagagtca gggcaaaagg tgaggtggtg   1680

aagtggcccg ggcctgggaa ctgctggctc taagaacctt ctattcacat ccatggattg   1740

ggcccactac tcatagcagc tcctgaggca ggtaaatggg gcaaggactc acgccaaata   1800

ccacacgcgt atgtcaaaca cccaaggtcg gattctgggg cccctgccct caggaggctg   1860

tcagactgtt ccccctaaac acacttctga aggttgtagg gaccttgccc tgctgtctgc   1920

cggccagagc ctctcccatc tgacccaggc caggcgttcc cacctctcct ccttgggagg   1980

ttccagtggg ttctggaggg agggtgggct gtgtgcagct ccgtcttttg ctcgccctcc   2040

taggttggtg tggttttttt cttttctcag gtgatatatc ccctgaagga ggtctacccc   2100

gactcaggtt ctgccgatga tgagaggatc ttgaggttct tggaattggc aggcctgtcc   2160

aacttggtgg caaggacaga gggcctggac cagcaggtgg actggaactg gtatgatgtt   2220

ctgtccccgg gggagatgca acggctctcc tttgcccgac tcttctacct gcagccgaag   2280

tacgcagtgc ttgatgaagc caccagtgcc ctgacagagg aagtggagag cgagctctat   2340

cgcatcggcc agcagctggg gatgacgttc atcagtgtgg gacatcggca gagccttgag   2400

aagtttcatt ccttggttct gaaactctgt ggaggaggaa gatgggagct gatgagaatc   2460

aaagtggaat gaagctctgg cttttggaag gagagccaca ctgtggcggg tcggcggccc   2520

tcaggagaga ccaggaggac tgacagcgaa gatcgagctc aggttcgcca catagatccc   2580

gtgcaggagc cacatgggtc ctgtgcagga cccctagcag tggtgggctg agcccaggtc   2640

taggtttctg tgggggacac tgaatctccc agtgttcagt ctcccaggac tctgctgcct   2700

cagccagagc ctccatatgc ttgaagtgct gattacctac aaatgatttc agatcatgtt   2760

tgctaaagag aaatctggaa gtgtgagatc tgtaagaaat gaaagaaatg actcttggag   2820

tcaagagatc tggaaatctt ttaatcagtt aaattgtgca gcaatagatt tttaacttta   2880

actgaccatt taagtttttt aataagtttt ttacaaagaa aagttaaaca ttaaaaagaa   2940

ttacagcttt ctgtcttctc tatcatggaa tgatcttttt tattgaatct ccagatttgt   3000

atttgacagc ttggtgggaa gggaagcaca ctctgctgtt ctggaatctt atgcccaggg   3060

tttttcactt ctccccacat ctccctttcc acttgccagt gttgtgtagt tagaacctga   3120

accactaact tccaggggcc tttggtctgc cctaccttaa cccaaatgaa agtaaatccc   3180

tttcccctta gccaaaataa ggttgggttt tctaaaaaaa tagtctatat tagggaacaa   3240

caacagcaaa ttagacaaaa cccagaaagc acaaagcatg aggtggagtt actgtgccca   3300

aagtcctcac tcagaccagt gcccctccag ttcagttgtc tatgtattac cttccttacc   3360

ttcataattt ttgccaggct tctgtacttc tagtacttga gttacttaat atttttaaaa   3420

acaaaccttt taagtttaaa tggattttta agtgaaattt tacacttaac atagatggaa   3480

agtaactaaa aataaataca agaaaaac                                      3508


<210>  8421
<211>  497
<212>  PRT
<213>  Homo sapiens

<400>  8421

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Leu 
                85                  90                  95


Lys Ser Phe Asp Gln Phe Thr Cys Asn Leu Leu Tyr Val Ser Trp Arg 
            100                 105                 110


Lys Asp Leu Thr Glu His Leu His Arg Leu Tyr Phe Arg Gly Arg Ala 
        115                 120                 125


Tyr Tyr Thr Leu Asn Val Leu Arg Asp Asp Ile Asp Asn Pro Asp Gln 
    130                 135                 140


Arg Ile Ser Gln Asp Val Glu Arg Phe Cys Arg Gln Leu Ser Ser Met 
145                 150                 155                 160


Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr Tyr 
                165                 170                 175


Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe Gly 
            180                 185                 190


Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro Ile 
        195                 200                 205


Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg Phe 
    210                 215                 220


Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr Arg 
225                 230                 235                 240


Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg Leu 
                245                 250                 255


Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr Ile 
            260                 265                 270


Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val Val 
        275                 280                 285


Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro Ala 
    290                 295                 300


Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr Leu 
305                 310                 315                 320


Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser Asp 
                325                 330                 335


Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu Leu 
            340                 345                 350


Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser Glu 
        355                 360                 365


Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala Asp 
    370                 375                 380


Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser Asp 
385                 390                 395                 400


Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln Ser 
                405                 410                 415


Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu Arg 
            420                 425                 430


Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met Leu 
        435                 440                 445


Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro Phe 
    450                 455                 460


Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ser Leu Val Gln Gly Ala 
465                 470                 475                 480


His Ser Ser Leu Leu Asn Pro Ala His Pro Gln Leu Gly Pro Leu Ala 
                485                 490                 495


Leu 



<210>  8422
<211>  3172
<212>  DNA
<213>  Homo sapiens

<400>  8422
cgcttccggg agagtccgcg tctcccgcac cttcctctct atcaaacgcc gtctctgtgg     60

tagccggggc cccgcccctc ctcggactct acccagtact gaactagggg cagctgggct    120

ccagagtccc tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc    180

aggcccaggt tagatctgca atttctccag cggttcctgc agatactgaa ggttttgttt    240

ccttcttggt catcacaaaa tgccttgatg ttcctgaccc ttttgtgcct gaccctactg    300

gagcaatttg tgatctacca ggttggcttg atccccagtc agtactatgg ggtcctggga    360

aacaaagact tggaagggtt taagactctg acattcctgg ctgtcatgct cattgttctg    420

aactccacgc tgaagagctt tgatcagttc acctgcaacc tgctgtatgt gagctggagg    480

aaggacctca ctgagcacct tcaccgcctc tacttccggg gccgtgcgta ctacaccctc    540

aacgtgctgc gggatgacat cgataacccg gaccagcgca tcagccagga cgtggagcga    600

ttctgccggc agctcagcag catggccagc aagctcatca tctccccgtt caccctcgtc    660

tactacactt accagtgctt ccaaagcaca ggctggctcg ggcctgtgag catcttcggg    720

tatttcatcc tggggaccgt ggtgaacaaa actttgatgg gccccattgt gatgaagctg    780

gtgcatcagg agaagctgga gggagatttt aggttcaagc acatgcagat tcgggtgaat    840

gcggagcctg ctgctttcta cagagctggg catgtggagc acatgaggac agaccgcagg    900

ctgcagagac tccttcagac ccagagggag ctgatgtcca aggagctctg gctgtacatc    960

ggcatcaaca cctttgacta tctgggcagc atcctgagtt acgttgtcat cgcaatcccc   1020

attttcagcg gggtctatgg agacctgagt cccgcagagc ttagcaccct ggtcagcaag   1080

aatgcctttg tgtgcatcta cctcatcagc tgcttcaccc agctcatcga cctgtccacg   1140

acgctctcag atgtggctgg ctacacgcac agaattgggc agcttcggga gacgcttctg   1200

gacatgtccc tgaagtcaca ggactgcgag atcctgggcg agagcgagtg gggcttggac   1260

acacccccag ggtggccagc ggcagagcca gcagacacag catttctcct tgagcgggtc   1320

tccatctctg ccccctcctc tgacaaaccc ctaatcaagg atctgagcct aaagatctcc   1380

gagggacaga gcctgctcat cacaggcaac acgggcactg gcaagacctc cttgctccgg   1440

gttctgggtg gcctctggac gagtacacgg ggctcagtgc agatgctgac ggactttggg   1500

ccccatgggg tgctattcct gccacaaaag ccattcttca ctgacgggac ccttcgggag   1560

caggtgatat atcccctgaa ggaggtctac cccgactcag gttctgccga tgatgagagg   1620

atcttgaggt tcttggaatt ggcaggcctg tccaacttgg tggcaaggac agagggcctg   1680

gaccagcagg tggactggaa ctggtatgat gttctgtccc cgggggagat gcaacggctc   1740

tcctttgccc gactcttcta cctgcagccg aagtacgcag tgcttgatga agccaccagt   1800

gccctgacag aggaagtgga gagcgagctc tatcgcatcg gccagcagct ggggatgacg   1860

ttcatcagtg tgggacatcg gcagagcctt gagaaggtac ccgtgctcac aaggatggcc   1920

tgaggaggag aaagaaccca aaggctcagc ctggccaggg ccagaggccc ctcaaaacgg   1980

ggagtagcag tagcagagag aaccgagtgg cctcctctgc cagcggccag ggcagcctga   2040

tctccatgtg gtggtggtct cttgtagttt cattccttgg ttctgaaact ctgtggagga   2100

ggaagatggg agctgatgag aatcaaagtg gaatgaagct ctggcttttg gaaggagagc   2160

cacactgtgg cgggtcggcg gccctcagga gagaccagga ggactgacag cgaagatcga   2220

gctcaggttc gccacataga tcccgtgcag gagccacatg ggtcctgtgc aggaccccta   2280

gcagtggtgg gctgagccca ggtctaggtt tctgtggggg acactgaatc tcccagtgtt   2340

cagtctccca ggactctgct gcctcagcca gagcctccat atgcttgaag tgctgattac   2400

ctacaaatga tttcagatca tgtttgctaa agagaaatct ggaagtgtga gatctgtaag   2460

aaatgaaaga aatgactctt ggagtcaaga gatctggaaa tcttttaatc agttaaattg   2520

tgcagcaata gatttttaac tttaactgac catttaagtt ttttaataag ttttttacaa   2580

agaaaagtta aacattaaaa agaattacag ctttctgtct tctctatcat ggaatgatct   2640

tttttattga atctccagat ttgtatttga cagcttggtg ggaagggaag cacactctgc   2700

tgttctggaa tcttatgccc agggtttttc acttctcccc acatctccct ttccacttgc   2760

cagtgttgtg tagttagaac ctgaaccact aacttccagg ggcctttggt ctgccctacc   2820

ttaacccaaa tgaaagtaaa tccctttccc cttagccaaa ataaggttgg gttttctaaa   2880

aaaatagtct atattaggga acaacaacag caaattagac aaaacccaga aagcacaaag   2940

catgaggtgg agttactgtg cccaaagtcc tcactcagac cagtgcccct ccagttcagt   3000

tgtctatgta ttaccttcct taccttcata atttttgcca ggcttctgta cttctagtac   3060

ttgagttact taatattttt aaaaacaaac cttttaagtt taaatggatt tttaagtgaa   3120

attttacact taacatagat ggaaagtaac taaaaataaa tacaagaaaa ac           3172


<210>  8423
<211>  592
<212>  PRT
<213>  Homo sapiens

<400>  8423

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Leu 
                85                  90                  95


Lys Ser Phe Asp Gln Phe Thr Cys Asn Leu Leu Tyr Val Ser Trp Arg 
            100                 105                 110


Lys Asp Leu Thr Glu His Leu His Arg Leu Tyr Phe Arg Gly Arg Ala 
        115                 120                 125


Tyr Tyr Thr Leu Asn Val Leu Arg Asp Asp Ile Asp Asn Pro Asp Gln 
    130                 135                 140


Arg Ile Ser Gln Asp Val Glu Arg Phe Cys Arg Gln Leu Ser Ser Met 
145                 150                 155                 160


Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr Tyr 
                165                 170                 175


Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe Gly 
            180                 185                 190


Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro Ile 
        195                 200                 205


Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg Phe 
    210                 215                 220


Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr Arg 
225                 230                 235                 240


Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg Leu 
                245                 250                 255


Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr Ile 
            260                 265                 270


Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val Val 
        275                 280                 285


Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro Ala 
    290                 295                 300


Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr Leu 
305                 310                 315                 320


Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser Asp 
                325                 330                 335


Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu Leu 
            340                 345                 350


Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser Glu 
        355                 360                 365


Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala Asp 
    370                 375                 380


Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser Asp 
385                 390                 395                 400


Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln Ser 
                405                 410                 415


Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu Arg 
            420                 425                 430


Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met Leu 
        435                 440                 445


Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro Phe 
    450                 455                 460


Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys Glu 
465                 470                 475                 480


Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg Phe 
                485                 490                 495


Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly Leu 
            500                 505                 510


Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly Glu 
        515                 520                 525


Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
    530                 535                 540


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
545                 550                 555                 560


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
                565                 570                 575


Gly His Arg Gln Ser Leu Glu Lys Val Pro Val Leu Thr Arg Met Ala 
            580                 585                 590


<210>  8424
<211>  3001
<212>  DNA
<213>  Homo sapiens

<400>  8424
cgcttccggg agagtccgcg tctcccgcac cttcctctct atcaaacgcc gtctctgtgg     60

tagccggggc cccgcccctc ctcggactct acccagtact gaactagggg cagctgggct    120

ccagagtccc tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc    180

aggcccaggt tagatctgca atttctccag cggttcctgc agatactgaa ggttttgttt    240

ccttcttggt catcacaaaa tgccttgatg ttcctgaccc ttttgtgcct gaccctactg    300

gagcaatttg tgatctacca ggttggcttg atccccagtc agtactatgg ggtcctggga    360

aacaaagact tggaagggtt taagactctg acattcctgg ctgtcatgct cattgttctg    420

aactccacgc tgaagagctt tgatcagttc acctgcaacc tgctgtatgt gagctggagg    480

aaggacctca ctgagcacct tcaccgcctc tacttccggg gccgtgcgta ctacaccctc    540

aacgtgctgc gggatgacat cgataacccg gaccagcgca tcagccagga cgtggagcga    600

ttctgccggc agctcagcag catggccagc aagctcatca tctccccgtt caccctcgtc    660

tactacactt accagtgctt ccaaagcaca ggctggctcg ggcctgtgag catcttcggg    720

tatttcatcc tggggaccgt ggtgaacaaa actttgatgg gccccattgt gatgaagctg    780

gtgcatcagg agaagctgga gggagatttt aggttcaagc acatgcagat tcgggtgaat    840

gcggagcctg ctgctttcta cagagctggg catgtggagc acatgaggac agaccgcagg    900

ctgcagagac tccttcagac ccagagggag ctgatgtcca aggagctctg gctgtacatc    960

ggcatcaaca cctttgacta tctgggcagc atcctgagtt acgttgtcat cgcaatcccc   1020

attttcagcg gggtctatgg agacctgagt cccgcagagc ttagcaccct ggtcagcaag   1080

aatgcctttg tgtgcatcta cctcatcagc tgcttcaccc agctcatcga cctgtccacg   1140

acgctctcag atgtggctgg ctacacgcac agaattgggc agcttcggga gacgcttctg   1200

gacatgtccc tgaagtcaca ggactgcgag atcctgggcg agagcgagtg gggcttggac   1260

acacccccag ggtggccagc ggcagagcca gcagacacag catttctcct tgagcgggtc   1320

tccatctctg ccccctcctc tgacaaaccc ctaatcaagg atctgagcct aaagatctcc   1380

gagggacaga gcctgctcat cacaggcaac acgggcactg gcaagacctc cttgctccgg   1440

gttctgggtg gcctctggac gagtacacgg ggctcagtgc agatgctgac ggactttggg   1500

ccccatgggg tgctattcct gccacaaaag ccattcttca ctgacgggac ccttcgggag   1560

caggtgatat atcccctgaa ggaggtctac cccgactcag gttctgccga tgatgagagg   1620

atcttgaggt tcttggaatt ggcaggcctg tccaacttgg tggcaaggac agagggcctg   1680

gaccagcagg tggactggaa ctggtatgat gttctgtccc cgggggagat gcaacggctc   1740

tcctttgccc gactcttcta cctgcagccg aagtacgcag tgcttgatga agccaccagt   1800

gccctgacag aggaagtgga gagcgagctc tatcgcatcg gccagcagct ggggatgacg   1860

ttcatcagtg tgggacatcg gcagagcctt gagaagtttc attccttggt tctgaaactc   1920

tgtggaggag gaagatggga gctgatgaga atcaaagtgg aatgaagctc tggcttttgg   1980

aaggagagcc acactgtggc gggtcggcgg ccctcaggag agaccaggag gactgacagc   2040

gaagatcgag ctcaggttcg ccacatagat cccgtgcagg agccacatgg gtcctgtgca   2100

ggacccctag cagtggtggg ctgagcccag gtctaggttt ctgtggggga cactgaatct   2160

cccagtgttc agtctcccag gactctgctg cctcagccag agcctccata tgcttgaagt   2220

gctgattacc tacaaatgat ttcagatcat gtttgctaaa gagaaatctg gaagtgtgag   2280

atctgtaaga aatgaaagaa atgactcttg gagtcaagag atctggaaat cttttaatca   2340

gttaaattgt gcagcaatag atttttaact ttaactgacc atttaagttt tttaataagt   2400

tttttacaaa gaaaagttaa acattaaaaa gaattacagc tttctgtctt ctctatcatg   2460

gaatgatctt ttttattgaa tctccagatt tgtatttgac agcttggtgg gaagggaagc   2520

acactctgct gttctggaat cttatgccca gggtttttca cttctcccca catctccctt   2580

tccacttgcc agtgttgtgt agttagaacc tgaaccacta acttccaggg gcctttggtc   2640

tgccctacct taacccaaat gaaagtaaat ccctttcccc ttagccaaaa taaggttggg   2700

ttttctaaaa aaatagtcta tattagggaa caacaacagc aaattagaca aaacccagaa   2760

agcacaaagc atgaggtgga gttactgtgc ccaaagtcct cactcagacc agtgcccctc   2820

cagttcagtt gtctatgtat taccttcctt accttcataa tttttgccag gcttctgtac   2880

ttctagtact tgagttactt aatattttta aaaacaaacc ttttaagttt aaatggattt   2940

ttaagtgaaa ttttacactt aacatagatg gaaagtaact aaaaataaat acaagaaaaa   3000

c                                                                   3001


<210>  8425
<211>  606
<212>  PRT
<213>  Homo sapiens

<400>  8425

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Leu 
                85                  90                  95


Lys Ser Phe Asp Gln Phe Thr Cys Asn Leu Leu Tyr Val Ser Trp Arg 
            100                 105                 110


Lys Asp Leu Thr Glu His Leu His Arg Leu Tyr Phe Arg Gly Arg Ala 
        115                 120                 125


Tyr Tyr Thr Leu Asn Val Leu Arg Asp Asp Ile Asp Asn Pro Asp Gln 
    130                 135                 140


Arg Ile Ser Gln Asp Val Glu Arg Phe Cys Arg Gln Leu Ser Ser Met 
145                 150                 155                 160


Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr Tyr 
                165                 170                 175


Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe Gly 
            180                 185                 190


Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro Ile 
        195                 200                 205


Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg Phe 
    210                 215                 220


Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr Arg 
225                 230                 235                 240


Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg Leu 
                245                 250                 255


Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr Ile 
            260                 265                 270


Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val Val 
        275                 280                 285


Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro Ala 
    290                 295                 300


Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr Leu 
305                 310                 315                 320


Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser Asp 
                325                 330                 335


Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu Leu 
            340                 345                 350


Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser Glu 
        355                 360                 365


Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala Asp 
    370                 375                 380


Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser Asp 
385                 390                 395                 400


Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln Ser 
                405                 410                 415


Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu Arg 
            420                 425                 430


Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met Leu 
        435                 440                 445


Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro Phe 
    450                 455                 460


Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys Glu 
465                 470                 475                 480


Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg Phe 
                485                 490                 495


Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly Leu 
            500                 505                 510


Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly Glu 
        515                 520                 525


Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
    530                 535                 540


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
545                 550                 555                 560


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
                565                 570                 575


Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu Lys Leu 
            580                 585                 590


Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
        595                 600                 605


<210>  8426
<211>  2867
<212>  DNA
<213>  Homo sapiens

<400>  8426
gtcggtcgct tccgggagag tccgcgtctc ccgcaccttc ctctctatca aacgccgtct     60

ctgtggtagc cggggccccg cccctcctcg gactctaccc agtactgaac taggggcagc    120

tgggctccag agtccctcgg gtctcaggtc atggcggtcg cggggcccgc gcccggagct    180

ggcgccaggc ccaggttaga tctgcaattt ctccagcggt tcctgcagat actgaaggtt    240

ttgtttcctt cttggtcatc acaaaatgcc ttgatgttcc tgaccctttt gtgcctgacc    300

ctactggagc aatttgtgat ctaccaggtt ggcttgatcc ccagtcagta ctatggggtc    360

ctgggaaaca aagacttgga agggtttaag actctgacat tcctggctgt catgctcatt    420

gttctgaact ccacgggacc agcgcatcag ccaggacgtg gagcgattct gccggcagct    480

cagcagcatg gccagcaagc tcatcatctc cccgttcacc ctcgtctact acacttacca    540

gtgcttccaa agcacaggct ggctcgggcc tgtgagcatc ttcgggtatt tcatcctggg    600

gaccgtggtg aacaaaactt tgatgggccc cattgtgatg aagctggtgc atcaggagaa    660

gctggaggga gattttaggt tcaagcacat gcagattcgg gtgaatgcgg agcctgctgc    720

tttctacaga gctgggcatg tggagcacat gaggacagac cgcaggctgc agagactcct    780

tcagacccag agggagctga tgtccaagga gctctggctg tacatcggca tcaacacctt    840

tgactatctg ggcagcatcc tgagttacgt tgtcatcgca atccccattt tcagcggggt    900

ctatggagac ctgagtcccg cagagcttag caccctggtc agcaagaatg cctttgtgtg    960

catctacctc atcagctgct tcacccagct catcgacctg tccacgacgc tctcagatgt   1020

ggctggctac acgcacagaa ttgggcagct tcgggagacg cttctggaca tgtccctgaa   1080

gtcacaggac tgcgagatcc tgggcgagag cgagtggggc ttggacacac ccccagggtg   1140

gccagcggca gagccagcag acacagcatt tctccttgag cgggtctcca tctctgcccc   1200

ctcctctgac aaacccctaa tcaaggatct gagcctaaag atctccgagg gacagagcct   1260

gctcatcaca ggcaacacgg gcactggcaa gacctccttg ctccgggttc tgggtggcct   1320

ctggacgagt acacggggct cagtgcagat gctgacggac tttgggcccc atggggtgct   1380

attcctgcca caaaagccat tcttcactga cgggaccctt cgggagcagg tgatatatcc   1440

cctgaaggag gtctaccccg actcaggttc tgccgatgat gagaggatct tgaggttctt   1500

ggaattggca ggcctgtcca acttggtggc aaggacagag ggcctggacc agcaggtgga   1560

ctggaactgg tatgatgttc tgtccccggg ggagatgcaa cggctctcct ttgcccgact   1620

cttctacctg cagccgaagt acgcagtgct tgatgaagcc accagtgccc tgacagagga   1680

agtggagagc gagctctatc gcatcggcca gcagctgggg atgacgttca tcagtgtggg   1740

acatcggcag agccttgaga agtttcattc cttggttctg aaactctgtg gaggaggaag   1800

atgggagctg atgagaatca aagtggaatg aagctctggc ttttggaagg agagccacac   1860

tgtggcgggt cggcggccct caggagagac caggaggact gacagcgaag atcgagctca   1920

ggttcgccac atagatcccg tgcaggagcc acatgggtcc tgtgcaggac ccctagcagt   1980

ggtgggctga gcccaggtct aggtttctgt gggggacact gaatctccca gtgttcagtc   2040

tcccaggact ctgctgcctc agccagagcc tccatatgct tgaagtgctg attacctaca   2100

aatgatttca gatcatgttt gctaaagaga aatctggaag tgtgagatct gtaagaaatg   2160

aaagaaatga ctcttggagt caagagatct ggaaatcttt taatcagtta aattgtgcag   2220

caatagattt ttaactttaa ctgaccattt aagtttttta ataagttttt tacaaagaaa   2280

agttaaacat taaaaagaat tacagctttc tgtcttctct atcatggaat gatctttttt   2340

attgaatctc cagatttgta tttgacagct tggtgggaag ggaagcacac tctgctgttc   2400

tggaatctta tgcccagggt ttttcacttc tccccacatc tccctttcca cttgccagtg   2460

ttgtgtagtt agaacctgaa ccactaactt ccaggggcct ttggtctgcc ctaccttaac   2520

ccaaatgaaa gtaaatccct ttccccttag ccaaaataag gttgggtttt ctaaaaaaat   2580

agtctatatt agggaacaac aacagcaaat tagacaaaac ccagaaagca caaagcatga   2640

ggtggagtta ctgtgcccaa agtcctcact cagaccagtg cccctccagt tcagttgtct   2700

atgtattacc ttccttacct tcataatttt tgccaggctt ctgtacttct agtacttgag   2760

ttacttaata tttttaaaaa caaacctttt aagtttaaat ggatttttaa gtgaaatttt   2820

acacttaaca tagatggaaa gtaactaaaa ataaatacaa gaaaaac                 2867


<210>  8427
<211>  447
<212>  PRT
<213>  Homo sapiens

<400>  8427

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg 
                85                  90                  95


Leu Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr 
            100                 105                 110


Ile Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val 
        115                 120                 125


Val Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro 
    130                 135                 140


Ala Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr 
145                 150                 155                 160


Leu Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser 
                165                 170                 175


Asp Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu 
            180                 185                 190


Leu Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser 
        195                 200                 205


Glu Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala 
    210                 215                 220


Asp Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser 
225                 230                 235                 240


Asp Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln 
                245                 250                 255


Ser Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu 
            260                 265                 270


Arg Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met 
        275                 280                 285


Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro 
    290                 295                 300


Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys 
305                 310                 315                 320


Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg 
                325                 330                 335


Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly 
            340                 345                 350


Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly 
        355                 360                 365


Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys 
    370                 375                 380


Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu 
385                 390                 395                 400


Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser 
                405                 410                 415


Val Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu Lys 
            420                 425                 430


Leu Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
        435                 440                 445


<210>  8428
<211>  1324
<212>  DNA
<213>  Homo sapiens

<400>  8428
ctgccctctg ggtctgttac agtccaactt ggtggcaagg acagagggcc tggaccagca     60

ggtggactgg aactggtaag aaaagagctt gggtgctcca gagatagccc caccataaag    120

acagtgggtt tcagggtccc tgtcaaggaa tggaacggct cctgacccca aagtccagat    180

gtttggctgg tcagtcgggt gcaagtttat gcccttggga acagagtttt gcctcactct    240

gtgagggctg taggcctatg gtcgaaaggg aaggggcttc tgtctcctgg ggctcacctc    300

tgtgcagaga aacctcttcc tacccagacc attctaggta aaagccaagc tatattcttc    360

ctcctctagc agtcctctct cctacctttc ctcaggtatg atgttctgtc cccgggggag    420

atgcaacggc tctcctttgc ccgactcttc tacctgcagc cgaagtacgc agtgcttgat    480

gaagccacca gtgccctgac agaggaagtg gagagcgagc tctatcgcat cggccagcag    540

ctggggatga cgttcatcag tgtgggacat cggcagagcc ttgagaaggt acccgtgctc    600

acaaggatgg cctgaggagg agaaagaacc caaaggctca gcctggccag ggccagaggc    660

ccctcaaaac ggggagtagc agtagcagag agaaccgagt ggcctcctct gccagcggcc    720

agggcagcct gatctccatg tggtggtggt ctcttgtagt ttcattcctt ggttctgaaa    780

ctctgtggag gaggaagatg ggagctgatg agaatcaaag tggaatgaag ctctggcttt    840

tggaaggaga gccacactgt ggcgggtcgg cggccctcag gagagaccag gaggactgac    900

agcgaagatc gagctcaggt tcgccacata gatcccgtgc aggagccaca tgggtcctgt    960

gcaggacccc tagcagtggt gggctgagcc caggtctagg tttctgtggg ggacactgaa   1020

tctcccagtg ttcagtctcc caggactctg ctgcctcagc cagagcctcc atatgcttga   1080

agtgctgatt acctacaaat gatttcagat catgtttgct aaagagaaat ctggaagtgt   1140

gagatctgta agaaatgaaa gaaatgactc ttggagtcaa gagatctgga aatcttttaa   1200

tcagttaaat tgtgcagcaa tagattttta actttaactg accatttaag ttttttaata   1260

agttttttac aaagaaaagt taaacattaa aaagaattac agctttctgt cttctctatc   1320

atgg                                                                1324


<210>  8429
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8429

Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
1               5                   10                  15


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
            20                  25                  30


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
        35                  40                  45


Gly His Arg Gln Ser Leu Glu Lys Val Pro Val Leu Thr Arg Met Ala 
    50                  55                  60


<210>  8430
<211>  904
<212>  DNA
<213>  Homo sapiens

<400>  8430
tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc agtgcttgat     60

gaagccacca gtgccctgac agaggaagtg gagagcgagc tctatcgcat cggccagcag    120

ctggggatga cgttcatcag tgtgggacat cggcagagcc ttgagaaggt acccgtgctc    180

acaaggatgg cctgaggagg agaaagaacc caaaggctca gcctggccag ggccagaggc    240

ccctcaaaac ggggagtagc agtagcagag agaaccgagt ggcctcctct gccagcggcc    300

agggcagcct gatctccatg tggtggtggt ctcttgtagt ttcattcctt ggttctgaaa    360

ctctgtggag gaggaagatg ggagctgatg agaatcaaag tggaatgaag ctctggcttt    420

tggaaggaga gccacactgt ggcgggtcgg cggccctcag gagagaccag gaggactgac    480

agcgaagatc gagctcaggt tcgccacata gatcccgtgc aggagccaca tgggtcctgt    540

gcaggacccc tagcagtggt gggctgagcc caggtctagg tttctgtggg ggacactgaa    600

tctcccagtg ttcagtctcc caggactctg ctgcctcagc cagagcctcc atatgcttga    660

agtgctgatt acctacaaat gatttcagat catgtttgct aaagagaaat ctggaagtgt    720

gagatctgta agaaatgaaa gaaatgactc ttggagtcaa gagatctgga aatcttttaa    780

tcagttaaat tgtgcagcaa tagattttta actttaactg accatttaag ttttttaata    840

agttttttac aaagaaaagt taaacattaa aaagaattac agctttctgt cttctctatc    900

atgg                                                                 904


<210>  8431
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8431

Met Trp Trp Trp Ser Leu Val Val Ser Phe Leu Gly Ser Glu Thr Leu 
1               5                   10                  15


Trp Arg Arg Lys Met Gly Ala Asp Glu Asn Gln Ser Gly Met Lys Leu 
            20                  25                  30


Trp Leu Leu Glu Gly Glu Pro His Cys Gly Gly Ser Ala Ala Leu Arg 
        35                  40                  45


Arg Asp Gln Glu Asp 
    50


<210>  8432
<211>  2503
<212>  DNA
<213>  Homo sapiens

<400>  8432
gcttccggga gagtccgcgt ctcccgcacc ttcctctcta tcaaacgccg tctctgtggt     60

agccggggcc ccgcccctcc tcggactcta cccagtactg aactaggggc agctgggctc    120

cagagtccct cgggtctcag gtcatggcgg tcgcggggcc cgcgcccgga gctggcgcca    180

ggcccaggtt agatctgcaa tttctccagc ggttcctgca gatactgaag gttttgtttc    240

cttcttggtc atcacaaaat gccttgatgt tcctgaccct tttgtgcctg accctactgg    300

ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc    360

actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg    420

cgggatgaca tcgataaccc ggaccagcgc atcagccagg acgtggagcg attctgccgg    480

cagctcagca gcatggccag caagctcatc atctccccgt tcaccctcgt ctactacact    540

taccagtgct tccaaagcac aggctggctc gggcctgtga gcatcttcgg gtatttcatc    600

ctggggaccg tggtgaacaa aactttgatg ggccccattg tgatgaagct ggtgcatcag    660

gagaagctgg agggagattt taggttcaag cacatgcaga ttcgggtgaa tgcggagcct    720

gctgctttct acagagctgg gcatgtggag cacatgagga cagaccgcag gctgcagaga    780

ctccttcaga cccagaggga gctgatgtcc aaggagctct ggctgtacat cggcatcaac    840

acctttgact atctgggcag catcctgagt tacgttgtca tcgcaatccc cattttcagc    900

ggggtctatg gagacctgag tcccgcagag cttagcaccc tggtcagcaa gaatgccttt    960

gtgtgcatct acctcatcag ctgcttcacc cagctcatcg acctgtccac gacgctctca   1020

gatgtggctg gctacacgca cagaattggg cagcttcggg agacgcttct ggacatgtcc   1080

ctgaagtcac aggactgcga gatcctgggc gagagcgagt ggggcttgga cacaccccca   1140

gggtggccag cggcagagcc agcagacaca gcatttctcc ttgagcgggt ctccatctct   1200

gccccctcct ctgacaaacc cctaatcaag gatctgagcc taaagatctc cgagggacag   1260

agcctgctca tcacaggcaa cacgggcact ggcaagacct ccttgctccg ggttctgggt   1320

ggcctctgga cgagtacacg gggctcagtg cagatgctga cggactttgg gccccatggg   1380

gtgctattcc tgccacaaaa gccattcttc actgacggga cccttcggga gcaggtgata   1440

tatcccctga aggaggtcta ccccgactca ggttctgccg atgatgagag gatcttgagg   1500

ttcttggaat tggcaggcct gtccaacttg gtggcaagga cagagggcct ggaccagcag   1560

gtggactgga actggtatga tgttctgtcc ccgggggaga tgcaacggct ctcctttgcc   1620

cgactcttct acctgcagcc gaagtacgca gtgcttgatg aagccaccag tgccctgaca   1680

gaggaagtgg agagcgagct ctatcgcatc ggccagcagc tggggatgac gttcatcagt   1740

gtgggacatc ggcagagcct tgagaaggta cccgtgctca caaggatggc ctgaggagga   1800

gaaagaaccc aaaggctcag cctggccagg gccagaggcc cctcaaaacg gggagtagca   1860

gtagcagaga gaaccgagtg gcctcctctg ccagcggcca gggcagcctg atctccatgt   1920

ggtggtggtc tcttgtagtt tcattccttg gttctgaaac tctgtggagg aggaagatgg   1980

gagctgatga gaatcaaagt ggaatgaagc tctggctttt ggaaggagag ccacactgtg   2040

gcgggtcggc ggccctcagg agagaccagg aggactgaca gcgaagatcg agctcaggtt   2100

cgccacatag atcccgtgca ggagccacat gggtcctgtg caggacccct agcagtggtg   2160

ggctgagccc aggtctaggt ttctgtgggg gacactgaat ctcccagtgt tcagtctccc   2220

aggactctgc tgcctcagcc agagcctcca tatgcttgaa gtgctgatta cctacaaatg   2280

atttcagatc atgtttgcta aagagaaatc tggaagtgtg agatctgtaa gaaatgaaag   2340

aaatgactct tggagtcaag agatctggaa atcttttaat cagttaaatt gtgcagcaat   2400

agatttttaa ctttaactga ccatttaagt tttttaataa gttttttaca aagaaaagtt   2460

aaacattaaa aagaattaca gctttctgtc ttctctatca tgg                     2503


<210>  8433
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  8433

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg 
                85                  90                  95


Leu Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr 
            100                 105                 110


Ile Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val 
        115                 120                 125


Val Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro 
    130                 135                 140


Ala Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr 
145                 150                 155                 160


Leu Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser 
                165                 170                 175


Asp Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu 
            180                 185                 190


Leu Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser 
        195                 200                 205


Glu Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala 
    210                 215                 220


Asp Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser 
225                 230                 235                 240


Asp Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln 
                245                 250                 255


Ser Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu 
            260                 265                 270


Arg Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met 
        275                 280                 285


Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro 
    290                 295                 300


Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys 
305                 310                 315                 320


Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg 
                325                 330                 335


Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly 
            340                 345                 350


Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly 
        355                 360                 365


Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys 
    370                 375                 380


Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu 
385                 390                 395                 400


Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser 
                405                 410                 415


Val Gly His Arg Gln Ser Leu Glu Lys Val Pro Val Leu Thr Arg Met 
            420                 425                 430


Ala 



<210>  8434
<211>  900
<212>  DNA
<213>  Homo sapiens

<400>  8434
caggtgatat atcccctgaa ggaggtctac cccgactcag gttctgccga tgatgagagg     60

atcttgaggt tcttggaatt ggcaggcctg tccaacttgg tggcaaggac agagggcctg    120

gaccagcagg tggactggaa ctggtatgat gttctgtccc cgggggagat gcaacggctc    180

tcctttgccc gactcttcta cctgcagccg aagtacgcag tgcttgatga agccaccagt    240

gccctgacag aggaagtgga gagcgagctc tatcgcatcg gccagcagct ggggatgacg    300

ttcatcagtg tgggacatcg gcagagcctt gagaagtttc attccttggt tctgaaactc    360

tgtggaggag gaagatggga gctgatgaga atcaaagtgg aatgaagctc tggcttttgg    420

aaggagagcc acactgtggc gggtcggcgg ccctcaggag agaccaggag gactgacagc    480

gaagatcgag ctcaggttcg ccacatagat cccgtgcagg agccacatgg gtcctgtgca    540

ggacccctag cagtggtggg ctgagcccag gtctaggttt ctgtggggga cactgaatct    600

cccagtgttc agtctcccag gactctgctg cctcagccag agcctccata tgcttgaagt    660

gctgattacc tacaaatgat ttcagatcat gtttgctaaa gagaaatctg gaagtgtgag    720

atctgtaaga aatgaaagaa atgactcttg gagtcaagag atctggaaat cttttaatca    780

gttaaattgt gcagcaatag atttttaact ttaactgacc atttaagttt tttaataagt    840

tttttacaaa gaaaagttaa acattaaaaa gaattacagc tttctgtctt ctctatcatg    900


<210>  8435
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  8435

Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
1               5                   10                  15


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
            20                  25                  30


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
        35                  40                  45


Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu Lys Leu 
    50                  55                  60


Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
65                  70                  75


<210>  8436
<211>  1051
<212>  DNA
<213>  Homo sapiens

<400>  8436
ggatctgagc ctaaagatct ccgagggaca gagcctgctc atcacaggca acacgggcac     60

tggctcagtg cagatgctga cggactttgg gccccatggg gtgctattcc tgccacaaaa    120

gccattcttc actgacggga cccttcggga gcaggtgata tatcccctga aggaggtcta    180

ccccgactca ggttctgccg atgatgagag gatcttgagg ttcttggaat tggcaggcct    240

gtccaacttg gtggcaagga cagagggcct ggaccagcag gtggactgga actggtatga    300

tgttctgtcc ccgggggaga tgcaacggct ctcctttgcc cgactcttct acctgcagcc    360

gaagtacgca gtgcttgatg aagccaccag tgccctgaca gaggaagtgg agagcgagct    420

ctatcgcatc ggccagcagc tggggatgac gttcatcagt gtgggacatc ggcagagcct    480

tgagaagttt cattccttgg ttctgaaact ctgtggagga ggaagatggg agctgatgag    540

aatcaaagtg gaatgaagct ctggcttttg gaaggagagc cacactgtgg cgggtcggcg    600

gccctcagga gagaccagga ggactgacag cgaagatcga gctcaggttc gccacataga    660

tcccgtgcag gagccacatg ggtcctgtgc aggaccccta gcagtggtgg gctgagccca    720

ggtctaggtt tctgtggggg acactgaatc tcccagtgtt cagtctccca ggactctgct    780

gcctcagcca gagcctccat atgcttgaag tgctgattac ctacaaatga tttcagatca    840

tgtttgctaa agagaaatct ggaagtgtga gatctgtaag aaatgaaaga aatgactctt    900

ggagtcaaga gatctggaaa tcttttaatc agttaaattg tgcagcaata gatttttaac    960

tttaactgac catttaagtt ttttaataag ttttttacaa agaaaagtta aacattaaaa   1020

agaattacag ctttctgtct tctctatcat g                                  1051


<210>  8437
<211>  160
<212>  PRT
<213>  Homo sapiens

<400>  8437

Met Leu Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys 
1               5                   10                  15


Pro Phe Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu 
            20                  25                  30


Lys Glu Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu 
        35                  40                  45


Arg Phe Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu 
    50                  55                  60


Gly Leu Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro 
65                  70                  75                  80


Gly Glu Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro 
                85                  90                  95


Lys Tyr Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val 
            100                 105                 110


Glu Ser Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile 
        115                 120                 125


Ser Val Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu 
    130                 135                 140


Lys Leu Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
145                 150                 155                 160


<210>  8438
<211>  2460
<212>  DNA
<213>  Homo sapiens

<400>  8438
cgcttccggg agagtccgcg tctcccgcac cttcctctct atcaaacgcc gtctctgtgg     60

tagccggggc cccgcccctc ctcggactct acccagtact gaactagggg cagctgggct    120

ccagagtccc tcgggtctca ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc    180

aggcccaggt tagatctgca atttctccag cggttcctgc agatactgaa ggttttgttt    240

ccttcttggt catcacaaaa tgccttgatg ttcctgaccc ttttgtgcct gaccctactg    300

gagcaatttg tgatctacca ggttggcttg atccccagtc agtactatgg ggtcctggga    360

aacaaagact tggaagggtt taagactctg acattcctgg ctgtcatgct cattgttctg    420

aactccacgc tgaagagctt tgatcagttc acctgcaacc tgctgtatgt gagctggagg    480

aaggacctca ctgagcacct tcaccgcctc tacttccggg gccgtgcgta ctacaccctc    540

aacgtgctgc gggatgacat cgataacccg gaccagcgca tcagccagga cgtggagcga    600

ttctgccggc agctcagcag catggccagc aagctcatca tctccccgtt caccctcgtc    660

tactacactt accagtgctt ccaaagcaca ggctggctcg ggcctgtgag catcttcggg    720

tatttcatcc tggggaccgt ggtgaacaaa actttgatgg gccccattgt gatgaagctg    780

gtgcatcagg agaagctgga gggagatttt aggttcaagc acatgcagat tcgggtgaat    840

gcggagcctg ctgctttcta cagagctggg catgtggagc acatgaggac agaccgcagg    900

ctgcagagac tccttcagac ccagagggag ctgatgtcca aggagctctg gctgtacatc    960

ggcatcaaca cctttgacta tctgggcagc atcctgagtt acgttgtcat cgcaatcccc   1020

attttcagcg gggtctatgg agacctgagt cccgcagagc ttagcaccct ggtcagcaag   1080

aatgcctttg tgtgcatcta cctcatcagc tgcttcaccc agctcatcga cctgtccacg   1140

acgctctcag atgtggctgg ctacacgcac agaattgggc agcttcggga gacgcttctg   1200

gacatgtccc tgaagtcaca ggactgcgag atcctgggcg agagcgagtg gggcttggac   1260

acacccccag ggtggccagc ggcagagcca gcagacacag catttctcct tgagcgggtc   1320

tccatctctg ccccctcctc tgacaaaccc ctaatcaagg atctgagcct aaagatctcc   1380

gagggacaga gcctgctcat cacaggcaac acgggcactg gcaagacctc cttgctccgg   1440

gttctgggtg gcctctggac gagtacacgg ggctcagtgc agatgctgac ggactttggg   1500

ccccatgggg tgctattcct gccacaaaag ccattcttca ctgacgggac ccttcgggag   1560

caggtgatat atcccctgaa ggaggtctac cccgactcag gttctgccga tgatgagagg   1620

atcttgaggt tcttggaatt ggcaggcctg tccaacttgg tggcaaggac agagggcctg   1680

gaccagcagg tggactggaa ctggtatgat gttctgtccc cgggggagat gcaacggctc   1740

tcctttgccc gactcttcta cctgcagccg aagtacgcag tgcttgatga agccaccagt   1800

gccctgacag aggaagtgga gagcgagctc tatcgcatcg gccagcagct ggggatgacg   1860

ttcatcagtg tgggacatcg gcagagcctt gagaagtttc attccttggt tctgaaactc   1920

tgtggaggag gaagatggga gctgatgaga atcaaagtgg aatgaagctc tggcttttgg   1980

aaggagagcc acactgtggc gggtcggcgg ccctcaggag agaccaggag gactgacagc   2040

gaagatcgag ctcaggttcg ccacatagat cccgtgcagg agccacatgg gtcctgtgca   2100

ggacccctag cagtggtggg ctgagcccag gtctaggttt ctgtggggga cactgaatct   2160

cccagtgttc agtctcccag gactctgctg cctcagccag agcctccata tgcttgaagt   2220

gctgattacc tacaaatgat ttcagatcat gtttgctaaa gagaaatctg gaagtgtgag   2280

atctgtaaga aatgaaagaa atgactcttg gagtcaagag atctggaaat cttttaatca   2340

gttaaattgt gcagcaatag atttttaact ttaactgacc atttaagttt tttaataagt   2400

tttttacaaa gaaaagttaa acattaaaaa gaattacagc tttctgtctt ctctatcatg   2460


<210>  8439
<211>  606
<212>  PRT
<213>  Homo sapiens

<400>  8439

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Leu 
                85                  90                  95


Lys Ser Phe Asp Gln Phe Thr Cys Asn Leu Leu Tyr Val Ser Trp Arg 
            100                 105                 110


Lys Asp Leu Thr Glu His Leu His Arg Leu Tyr Phe Arg Gly Arg Ala 
        115                 120                 125


Tyr Tyr Thr Leu Asn Val Leu Arg Asp Asp Ile Asp Asn Pro Asp Gln 
    130                 135                 140


Arg Ile Ser Gln Asp Val Glu Arg Phe Cys Arg Gln Leu Ser Ser Met 
145                 150                 155                 160


Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr Tyr 
                165                 170                 175


Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe Gly 
            180                 185                 190


Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro Ile 
        195                 200                 205


Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg Phe 
    210                 215                 220


Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr Arg 
225                 230                 235                 240


Ala Gly His Val Glu His Met Arg Thr Asp Arg Arg Leu Gln Arg Leu 
                245                 250                 255


Leu Gln Thr Gln Arg Glu Leu Met Ser Lys Glu Leu Trp Leu Tyr Ile 
            260                 265                 270


Gly Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val Val 
        275                 280                 285


Ile Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro Ala 
    290                 295                 300


Glu Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr Leu 
305                 310                 315                 320


Ile Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser Asp 
                325                 330                 335


Val Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu Leu 
            340                 345                 350


Asp Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser Glu 
        355                 360                 365


Trp Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala Asp 
    370                 375                 380


Thr Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser Asp 
385                 390                 395                 400


Lys Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln Ser 
                405                 410                 415


Leu Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu Arg 
            420                 425                 430


Val Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Ser Val Gln Met Leu 
        435                 440                 445


Thr Asp Phe Gly Pro His Gly Val Leu Phe Leu Pro Gln Lys Pro Phe 
    450                 455                 460


Phe Thr Asp Gly Thr Leu Arg Glu Gln Val Ile Tyr Pro Leu Lys Glu 
465                 470                 475                 480


Val Tyr Pro Asp Ser Gly Ser Ala Asp Asp Glu Arg Ile Leu Arg Phe 
                485                 490                 495


Leu Glu Leu Ala Gly Leu Ser Asn Leu Val Ala Arg Thr Glu Gly Leu 
            500                 505                 510


Asp Gln Gln Val Asp Trp Asn Trp Tyr Asp Val Leu Ser Pro Gly Glu 
        515                 520                 525


Met Gln Arg Leu Ser Phe Ala Arg Leu Phe Tyr Leu Gln Pro Lys Tyr 
    530                 535                 540


Ala Val Leu Asp Glu Ala Thr Ser Ala Leu Thr Glu Glu Val Glu Ser 
545                 550                 555                 560


Glu Leu Tyr Arg Ile Gly Gln Gln Leu Gly Met Thr Phe Ile Ser Val 
                565                 570                 575


Gly His Arg Gln Ser Leu Glu Lys Phe His Ser Leu Val Leu Lys Leu 
            580                 585                 590


Cys Gly Gly Gly Arg Trp Glu Leu Met Arg Ile Lys Val Glu 
        595                 600                 605


<210>  8440
<211>  943
<212>  DNA
<213>  Homo sapiens

<400>  8440
ccaggactgg aagtctgaac ctggggtgga gaatgggagt atcagttgac agtgtgtgct     60

gttggccagg tttaggcacg aagggggtag tgctctcatt ggagaatttt aaaacaagaa    120

taggattgat gaaggcggtt tgctttttac tgtcatcatg ctccagcaag tctaaacagt    180

gtcattggta gaatattcct ctctgcctgg ggcagactgt cccacagtcc cccgccttgg    240

tatgccactg gggcatatat ttgtcttaga ggtgtgtgtg tatgctgggg agtgagggag    300

gttccccatg atggcaggta gcagggctgg ccatttcatg gacatcctgc cctctgggtc    360

tgttacagtc caacttggtg gcaaggacag agggcctgga ccagcaggtg gactggaact    420

ggtaagaaaa gagcttgggt gctccagaga tagccccacc ataaagacag tgggtttcag    480

ggtccctgtc aaggaatgga acggctcctg accccaaagt ccagatgttt ggctggtcag    540

tcgggtgcaa gtttatgccc ttgggaacag agttttgcct cactctgtga gggctgtagg    600

cctatggtcg aaagggaagg ggcttctgtc tcctggggct cacctctgtg cagagaaacc    660

tcttcctacc cagaccattc taggtaaaaa gcctccatat gcttgaagtg ctgattacct    720

acaaatgatt tcagatcatg tttgctaaag agaaatctgg aagtgtgaga tctgtaagaa    780

atgaaagaaa tgactcttgg agtcaagaga tctggaaatc ttttaatcag ttaaattgtg    840

cagcaataga tttttaactt taactgacca tttaagtttt ttaataagtt ttttacaaag    900

aaaagttaaa cattaaaaag aattacagct ttctgtcttc tct                      943


<210>  8441
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  8441

Met Met Ala Gly Ser Arg Ala Gly His Phe Met Asp Ile Leu Pro Ser 
1               5                   10                  15


Gly Ser Val Thr Val Gln Leu Gly Gly Lys Asp Arg Gly Pro Gly Pro 
            20                  25                  30


Ala Gly Gly Leu Glu Leu Val Arg Lys Glu Leu Gly Cys Ser Arg Asp 
        35                  40                  45


Ser Pro Thr Ile Lys Thr Val Gly Phe Arg Val Pro Val Lys Glu Trp 
    50                  55                  60


Asn Gly Ser 
65


<210>  8442
<211>  1565
<212>  DNA
<213>  Homo sapiens

<400>  8442
agacaatacc attaaggcat gactgaagcc gtgaatgggc gctaccagta gacagatcct     60

gagaccaaga tcatttgaat ggccttggtt tctaaaggag ggtgtgatat gggacaggcc    120

gctgattcaa ggaagagggg ctcctctcct cttcctttga ctgttttggg gtctgtaccc    180

agatctcacc tcattctttc tgtccttaag gagagatgcc cactgggaca aggaaagtga    240

tgccttcctt cacccacccc ttcccttatg aagatctgca acctgtggtt tcaaagcctt    300

cgcccagcat tctgaggccc ccacccctgc atcatccatg atgtgccctg tctattcttt    360

tttttttttt tttttttttt ttttgagatg gagtttcact ctgtcaccca gactggagtg    420

cagtggtgtg atctcggctc actgcaacct ccacctcccg ggttcaagca attcccctgc    480

ctcagcctct tccgtagctg gggctacagg tgcacgccac cttgcctgcc taatttttgt    540

atatttagta gagacagcgt ttcaccatgt tggccagggt ggtctccatc tcctgacctt    600

gtgatccacc tgcctcggcc tcccaaagtg ttgggattac aggcgtgagc cactgtgcac    660

agccttgccc tgtctatttt gaccagccag gaggctctgg ctttttgcag aaggcttctt    720

tgttgtgcag gttctgccga tgatgagagg atcttgaggt tcttggaatt ggcaggcctg    780

gtaagtgggg agagggaccc tcaggacccg agcccacctg ggagcaccag ctacaggtag    840

gcaggtgctg gccctgctat gcttgggccc aggactggaa gtctgaacct ggggtggaga    900

atgggagtat cagttgacag tgtgtgctgt tggccaggtt taggcacgaa gggggtagtg    960

ctctcattgg agaattttaa aacaagaata ggattgatga aggcggtttg ctttttactg   1020

tcatcatgct ccagcaagtc taaacagtgt cattggtaga atattcctct ctgcctgggg   1080

cagactgtcc cacagtcccc cgccttggta tgccactggg gcatatattt gtcttagagg   1140

tgtgtgtgta tgctggggag tgagggaggt tccccatgat ggcaggtagc agggctggcc   1200

atttcatgga catcctgccc tctgggtctg ttacagtcca acttggtggc aaggacagag   1260

ggcctggacc agcaggtgga ctggaactgg taagaaaaga gcttgggtgc tccagagata   1320

gccccaccat aaagacagtg ggtttcaggg tccctgtcaa ggaatggaac ggctcctgac   1380

cccaaagtcc agatgtttgg ctggtcagtc gggtgcaagt ttatgccctt gggaacagag   1440

ttttgcctca ctctgtgagg gctgtaggcc tatggtcgaa agggaagggg cttctgtctc   1500

ctggggctca cctctgtgca gagaaacctc ttcctaccca gaccattcta ggtaaaagcc   1560

aagct                                                               1565


<210>  8443
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8443

Met Ala Leu Val Ser Lys Gly Gly Cys Asp Met Gly Gln Ala Ala Asp 
1               5                   10                  15


Ser Arg Lys Arg Gly Ser Ser Pro Leu Pro Leu Thr Val Leu Gly Ser 
            20                  25                  30


Val Pro Arg Ser His Leu Ile Leu Ser Val Leu Lys Glu Arg Cys Pro 
        35                  40                  45


Leu Gly Gln Gly Lys 
    50


<210>  8444
<211>  1701
<212>  DNA
<213>  Homo sapiens

<400>  8444
ccttcccaga ctcccttaat ggctaagcct atctgctgcc atggccctga gggcacactt     60

agtactcctg attccaagtg aagaatgcag tgtgcctgcc tgccctctgg actgagagct    120

cctcaaagac agagataatt ttctcatttc tttattgcac tagctaacta gtgcaatgcc    180

tggtacacct agtgaccgct ctgtgtatgt ttatttaaca atagttttta tttattgagg    240

gctccttatg tgcttggcac tttatattta gaaactttta attctaactc taacctatta    300

cataggtatt attggctcca ttttatagat taaaaaaact gaggcttgga ggcttaagta    360

gcctgcctgt gtcacgcagc tagtaactgg ccagagccag gatttgaact aggtctgccc    420

aactctagag tttatgttct tcacacagac aataccatta aggcatgact gaagccgtga    480

atgggcgcta ccagtagaca gatcctgaga ccaagatcat ttgaatggcc ttggtttcta    540

aaggagggtg tgatatggga caggcggccc cccaacctgg ctgaacctct ccagccctgt    600

ggacatccca gcctttcctt gtcagagctg ggcatgtgga gcacatgagg acagaccgca    660

ggctgcagag actccttcag acccagaggg agctgatgtc caaggagctc tggctgtaca    720

gtaggcgagg gggcccaggg aagtgggaac catggggttg gactggtctg cttcccttcc    780

cacacctctc tacctcctgt ctgcaaggat aaatgtgcca tgatgaagga attaaccggg    840

gatgaggagg gggggctgtt gcctttctgt gagtatcctc aggagaatga ggatccagag    900

agtccacgtg gccctacttg gcgtcctgct ccctgtctta gggttgtgtc cgctgtaggg    960

catgtggatg gttcctgggt gtctcacaga tgtgttttct acagtcggca tcaacacctt   1020

tgactatctg ggcagcatcc tgagttacgt tgtcatcgca atccccattt tcagcggggt   1080

ctatggagac ctgagtcccg cagagcttag caccctggtc agcaagaatg cctttgtgtg   1140

catctacctc atcagctgct tcacccagct catcgacctg tccacgacgc tctcagatgt   1200

ggctggctac acgcacagaa ttgggcagct tcgggagacg cttctggaca tgtccctgaa   1260

gtcacaggac tgcgagatcc tgggcgagag cgagtggggc ttggacacac ccccagggtg   1320

gccagcggca gagccagcag acacagcatt tctccttgag cgggtctcca tctctgcccc   1380

ctcctctgac aaacccctaa tcaaggatct gagcctaaag atctccgagg gacagagcct   1440

gctcatcaca ggcaacacgg gcactggcaa gacctccttg ctccgggttc tgggtggcct   1500

ctggacgagt acacggggtg atatatcccc tgaaggaggt ctaccccgac tcaggagaga   1560

tgcccactgg gacaaggaaa gtgatgcctt ccttcaccca ccccttccct tatgaagatc   1620

tgcaacctgt ggtttcaaag ccttcgccca gcattctgag gcccccaccc ctgcatcatc   1680

catgatgtgc cctgtctatt c                                             1701


<210>  8445
<211>  217
<212>  PRT
<213>  Homo sapiens

<400>  8445

Met Trp Met Val Pro Gly Cys Leu Thr Asp Val Phe Ser Thr Val Gly 
1               5                   10                  15


Ile Asn Thr Phe Asp Tyr Leu Gly Ser Ile Leu Ser Tyr Val Val Ile 
            20                  25                  30


Ala Ile Pro Ile Phe Ser Gly Val Tyr Gly Asp Leu Ser Pro Ala Glu 
        35                  40                  45


Leu Ser Thr Leu Val Ser Lys Asn Ala Phe Val Cys Ile Tyr Leu Ile 
    50                  55                  60


Ser Cys Phe Thr Gln Leu Ile Asp Leu Ser Thr Thr Leu Ser Asp Val 
65                  70                  75                  80


Ala Gly Tyr Thr His Arg Ile Gly Gln Leu Arg Glu Thr Leu Leu Asp 
                85                  90                  95


Met Ser Leu Lys Ser Gln Asp Cys Glu Ile Leu Gly Glu Ser Glu Trp 
            100                 105                 110


Gly Leu Asp Thr Pro Pro Gly Trp Pro Ala Ala Glu Pro Ala Asp Thr 
        115                 120                 125


Ala Phe Leu Leu Glu Arg Val Ser Ile Ser Ala Pro Ser Ser Asp Lys 
    130                 135                 140


Pro Leu Ile Lys Asp Leu Ser Leu Lys Ile Ser Glu Gly Gln Ser Leu 
145                 150                 155                 160


Leu Ile Thr Gly Asn Thr Gly Thr Gly Lys Thr Ser Leu Leu Arg Val 
                165                 170                 175


Leu Gly Gly Leu Trp Thr Ser Thr Arg Gly Asp Ile Ser Pro Glu Gly 
            180                 185                 190


Gly Leu Pro Arg Leu Arg Arg Asp Ala His Trp Asp Lys Glu Ser Asp 
        195                 200                 205


Ala Phe Leu His Pro Pro Leu Pro Leu 
    210                 215


<210>  8446
<211>  4498
<212>  DNA
<213>  Homo sapiens

<400>  8446
gagacagagt ttctctcttg ttgcccaggc tggagtgcag tgacataatc tcagctcact     60

gcaacctctg cctccctggt tcaagtgatt ctcctgcctt cgcctccttt cagagcaatt    120

tgtgatctac caggttggct tgatccccag tcagtactat ggggtcctgg gaaacaaaga    180

cttggaaggg tttaagactc tgacattcct ggctgtcatg ctcattgttc tgaactccac    240

gctgaagagc tttgatcagt tcacctgcaa cctgctgtat gtgagctgga ggaaggacct    300

cactgagcac cttcaccgcc tctacttccg gggccgtgcg tactacaccc tcaacgtgct    360

gcgggatgac atcgataacc cgtaggcgcc ccaactcagt cctttctaca ctctgtgtgg    420

tcctttcctt ctggcctagc cctggagact gctggtggca gacaccaagg agatcatctg    480

cagtcgtttt caaatgctgc tgcccagagt catgggggag ggtgccctgc agaggactcc    540

tggagaagct gcagggctgt gaataggcag ctaaaaagaa gaagcctgcc aggtgcagtg    600

gcatgcacct gtagtcccaa caactcagga ggctgaggca ggaggatcac ttgagcccag    660

gagtagtgca ccgtgagcac acttgggaat agccactgta ctctagcctg ggcaacatag    720

cagaaacccc catctcttaa aaaaaagaaa aatgttagga gcagctttct tttgtccttt    780

tcatacttta tatcttagtc ttccagtaag aagactaagg ggtttcttta gagggttcta    840

aagaaaatgt ccttgctaga aaaaccagct cttagatttt catcagtaaa aaaaattacc    900

actatccagg actcagtcta ggattcacat ctccattcta tcaccactca ggttataact    960

cttaaagtca ccaagcccca ggttcccctt ctgtaaaatg aggacaataa tagttcctat   1020

ctcaaagggt gtagtgagga tgaaatatca ttcatgtaat gcacatgtac agtgcttgac   1080

acatagcaag tgtttcagtg taagttagct attgttattt tacagatgag gaagctgaag   1140

cccagagatt gcaagtgact tgcccaaggt cacgtcactc attgggaata ggaatcagta   1200

tggccctagt ggtgagatga gacatagggg gtctccttca cacccatccc ctcactcacc   1260

accttcctag caagcacttt gttggttggg gtacctctca gctcaagctt agctttggtg   1320

caaagatgcg tgggaggctg ctgctgctgc ctaacttcta ggcctctttc tgatggctat   1380

ggcttccatc ctgcctctgc cccctgagta gctgggacta caggtgtgcc tcacagcctg   1440

gagctttcac agccagataa ctaaaggggc caggctaggg cttatataag agaaatttgg   1500

gaggattgag ataaagggga tagtcttctt gatcatccaa aacagctcat ctaccttcaa   1560

gtttttcttt ggctctgctc agagctggct caggcccctg ggtactggac ctttcagttc   1620

ccactttttc aggggattaa ctaaggcacc gtaagatgca actctctaga accctgttta   1680

aaggccctgg gatttagttg cccctaggaa accagccttg tctggttccc tcttcccata   1740

gggtcagtgt tcacagcact gtgaggcaag gtcaagagca gaggtgatgt gaaagtttct   1800

tgttctctct acctttgggc ccatctccct gggtccagct actctgtgtc attggctcca   1860

gggaccagcg catcagccag gacgtggagc gattctgccg gcagctcagc agcatggcca   1920

gcaagctcat catctccccg ttcaccctcg tctactacac ttaccagtgc ttccaaagca   1980

caggctggct cgggcctgtg agcatcttcg ggtatttcat cctggggacc gtggtgaaca   2040

aaactttgat gggccccatt gtgatgaagc tggtgcatca ggagaagctg gagggagatt   2100

ttaggttcaa gcacatgcag attcgggtga atgcggagcc tgctgctttc tacaggtgag   2160

tctggagaga tggttcccct tctgccttgc cagagctgag agtggagaag gaaagatgaa   2220

tcctcaaccc tcccaccacc accgagctca ggggctgagt gttgtcacac ttggctgtga   2280

ccctctccct ctacctcccc ctgcccttgc ctgcctcatc cttaggtcca ggggtttgct   2340

tctgaagctg gtggttcctt actgtggcca gctttagtct tagtggccta gcgtggggcc   2400

tgaaattgtc aaatgaatga atgcctcatc ctcttgctgg tgactgtaag acatccgtct   2460

gcctctgctc ttctgtctgt taagaagctt tcttgccagt gcctgaggtt caagcctgat   2520

cctttgtctc cgtagcgtgg gatggaatgg gagcttctca gaaaaccagg agacctgctc   2580

cccacaatgc tgtctaatgg agccaagcgt ctggtctcct gacggcagca gcaggagcag   2640

cagcagcggc atgaaatccc atcccttccc tccagggcca gaaccggtcc ctgtgctctg   2700

ccttatgtga ggcctctgaa atcagcgtta ggattgatag tgcaggcaga ggtttgcgtt   2760

taagaagtgg aagctactcc ttggctctgt acttggggtg gatgtgatag ccctgggacc   2820

tttgctcctc agtctctgct gcagtttgca acctccacca cttgagggca ccaagaatac   2880

tgggaatctg cgctggggtg gggttgtgag gtgggcaggg ctgggtgtgt aaaaaagttg   2940

cttttggagg ccgggcatgg tggctcatgc ctgtaatccc agcactttgg gaggccgagg   3000

cgggtggatt gcctgaggtc aagagttcga gaccagccat ggccaacatg gtgaaaccct   3060

gtctctacta aaaatacaaa aaattagctg agcatggtgg cgggcacctg taatcccagc   3120

tactggggag gctgaggcag gagaatcact tgaatccggg aggcagaggt tgcagtaagg   3180

caagatcctg ccattgcact ccagcctggg tgacagagca agactccgtc tcaaaaaaaa   3240

aaaaagaaaa aagttgcttt tggattctgc agcctctgct catgaagctc tggggaaggc   3300

aggttagttt gtagagtttc agatgagttc ttctgtggcc tctgtgcaaa atctgaaatc   3360

tccctccacc ttttctgcct agcgaatttc ttcccatcct tgaaacccca gatcacctcc   3420

tctggagagc cttcccagac tcccttaatg gctaagccta tctgctgcca tggccctgag   3480

ggcacactta gtactcctga ttccaagtga agaatgcagt gtgcctgcct gccctctgga   3540

ctgagagctc ctcaaagaca gagataattt tctcatttct ttattgcact agctaactag   3600

tgcaatgcct ggtacaccta gtgaccgctc tgtgtatgtt tatttaacaa tagtttttat   3660

ttattgaggg ctccttatgt gcttggcact ttatatttag aaacttttaa ttctaactct   3720

aacctattac ataggtatta ttggctccat tttatagatt aaaaaaactg aggcttggag   3780

gcttaagtag cctgcctgtg tcacgcagct agtaactggc cagagccagg atttgaacta   3840

ggtctgccca actctagagt ttatgttctt cacacagaca ataccattaa ggcatgactg   3900

aagccgtgaa tgggcgctac cagtagacag atcctgagac caagatcatt tgaatggcct   3960

tggtttctaa aggagggtgt gatatgggac aggcggcccc ccaacctggc tgaacctctc   4020

cagccctgtg gacatcccag cctttccttg tcagagctgg gcatgtggag cacatgagga   4080

cagaccgcag gctgcagaga ctccttcaga cccagaggga gctgatgtcc aaggagctct   4140

ggctgtacag taggcgaggg ggcccaggga agtgggaacc atggggttgg actggtctgc   4200

ttcccttccc acacctctct acctcctgtc tgcaaggata aatgtgccat gatgaaggaa   4260

ttaaccgggg atgaggaggg ggggctgttg cctttctgtg agtatcctca ggagaatgag   4320

gatccagaga gtccacgtgg ccctacttgg cgtcctgctc cctgtcttag ggttgtgtcc   4380

gctgtagggc atgtggatgg ttcctgggtg tctcacagat gtgttttcta cagtcggcat   4440

caacaccttt gactatctgg gcagcatcct gagttacgtt gtcatcgcaa tccccatt     4498


<210>  8447
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  8447

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg 



<210>  8448
<211>  3077
<212>  DNA
<213>  Homo sapiens

<400>  8448
gcttccggga gagtccgcgt ctcccgcacc ttcctctcta tcaaacgccg tctctgtggt     60

agccggggcc ccgcccctcc tcggactcta cccagtactg aactaggggc agctgggctc    120

cagagtccct cgggtctcag gtcatggcgg tcgcggggcc cgcgcccgga gctggcgcca    180

ggcccaggtt agatctgcaa tttctccagc ggttcctgca gatactgaag gttttgtttc    240

cttcttggtc atcacaaaat gccttgatgt tcctgaccct tttgtgcctg accctactgg    300

ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc    360

actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg    420

cgggatgaca tcgataaccc ggaccagcgc atcagccagg acgtggagcg attctgccgg    480

cagctcagca gcatggccag caagctcatc atctccccgt tcaccctcgt ctactacact    540

taccagtgct tccaaagcac aggctggctc gggcctgtga gcatcttcgg gtatttcatc    600

ctggggaccg tggtgaacaa aactttgatg ggccccattg tgatgaagct ggtgcatcag    660

gagaagctgg agggagattt taggttcaag cacatgcaga ttcgggtgaa tgcggagcct    720

gctgctttct acaggtgagt ctggagagat ggttcccctt ctgccttgcc agagctgaga    780

gtggagaagg aaagatgaat cctcaaccct cccaccacca ccgagctcag gggctgagtg    840

ttgtcacact tggctgtgac cctctccctc tacctccccc tgcccttgcc tgcctcatcc    900

ttaggtccag gggtttgctt ctgaagctgg tggttcctta ctgtggccag ctttagtctt    960

agtggcctag cgtggggcct gaaattgtca aatgaatgaa tgcctcatcc tcttgctggt   1020

gactgtaaga catccgtctg cctctgctct tctgtctgtt aagaagcttt cttgccagtg   1080

cctgaggttc aagcctgatc ctttgtctcc gtagcgtggg atggaatggg agcttctcag   1140

aaaaccagga gacctgctcc ccacaatgct gtctaatgga gccaagcgtc tggtctcctg   1200

acggcagcag caggagcagc agcagcggca tgaaatccca tcccttccct ccagggccag   1260

aaccggtccc tgtgctctgc cttatgtgag gcctctgaaa tcagcgttag gattgatagt   1320

gcaggcagag gtttgcgttt aagaagtgga agctactcct tggctctgta cttggggtgg   1380

atgtgatagc cctgggacct ttgctcctca gtctctgctg cagtttgcaa cctccaccac   1440

ttgagggcac caagaatact gggaatctgc gctggggtgg ggttgtgagg tgggcagggc   1500

tgggtgtgta aaaaagttgc ttttggaggc cgggcatggt ggctcatgcc tgtaatccca   1560

gcactttggg aggccgaggc gggtggattg cctgaggtca agagttcgag accagccatg   1620

gccaacatgg tgaaaccctg tctctactaa aaatacaaaa aattagctga gcatggtggc   1680

gggcacctgt aatcccagct actggggagg ctgaggcagg agaatcactt gaatccggga   1740

ggcagaggtt gcagtaaggc aagatcctgc cattgcactc cagcctgggt gacagagcaa   1800

gactccgtct caaaaaaaaa aaaagaaaaa agttgctttt ggattctgca gcctctgctc   1860

atgaagctct ggggaaggca ggttagtttg tagagtttca gatgagttct tctgtggcct   1920

ctgtgcaaaa tctgaaatct ccctccacct tttctgccta gcgaatttct tcccatcctt   1980

gaaaccccag atcacctcct ctggagagcc ttcccagact cccttaatgg ctaagcctat   2040

ctgctgccat ggccctgagg gcacacttag tactcctgat tccaagtgaa gaatgcagtg   2100

tgcctgcctg ccctctggac tgagagctcc tcaaagacag agataatttt ctcatttctt   2160

tattgcacta gctaactagt gcaatgcctg gtacacctag tgaccgctct gtgtatgttt   2220

atttaacaat agtttttatt tattgagggc tccttatgtg cttggcactt tatatttaga   2280

aacttttaat tctaactcta acctattaca taggtattat tggctccatt ttatagatta   2340

aaaaaactga ggcttggagg cttaagtagc ctgcctgtgt cacgcagcta gtaactggcc   2400

agagccagga tttgaactag gtctgcccaa ctctagagtt tatgttcttc acacagacaa   2460

taccattaag gcatgactga agccgtgaat gggcgctacc agtagacaga tcctgagacc   2520

aagatcattt gaatggcctt ggtttctaaa ggagggtgtg atatgggaca ggcggccccc   2580

caacctggct gaacctctcc agccctgtgg acatcccagc ctttccttgt cagagctggg   2640

catgtggagc acatgaggac agaccgcagg ctgcagagac tccttcagac ccagagggag   2700

ctgatgtcca aggagctctg gctgtacagt aggcgagggg gcccagggaa gtgggaacca   2760

tggggttgga ctggtctgct tcccttccca cacctctcta cctcctgtct gcaaggataa   2820

atgtgccatg atgaaggaat taaccgggga tgaggagggg gggctgttgc ctttctgtga   2880

gtatcctcag gagaatgagg atccagagag tccacgtggc cctacttggc gtcctgctcc   2940

ctgtcttagg gttgtgtccg ctgtagggca tgtggatggt tcctgggtgt ctcacagatg   3000

tgttttctac agtcggcatc aacacctttg actatctggg cagcatcctg agttacgttg   3060

tcatcgcaat ccccatt                                                  3077


<210>  8449
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  8449

Met Ala Ser Lys Leu Ile Ile Ser Pro Phe Thr Leu Val Tyr Tyr Thr 
1               5                   10                  15


Tyr Gln Cys Phe Gln Ser Thr Gly Trp Leu Gly Pro Val Ser Ile Phe 
            20                  25                  30


Gly Tyr Phe Ile Leu Gly Thr Val Val Asn Lys Thr Leu Met Gly Pro 
        35                  40                  45


Ile Val Met Lys Leu Val His Gln Glu Lys Leu Glu Gly Asp Phe Arg 
    50                  55                  60


Phe Lys His Met Gln Ile Arg Val Asn Ala Glu Pro Ala Ala Phe Tyr 
65                  70                  75                  80


Arg 



<210>  8450
<211>  456
<212>  DNA
<213>  Homo sapiens

<400>  8450
agagtccctc gggtctcagg tcatggcggt cgcggggccc gcgcccggag ctggcgccag     60

gcccaggtta gatctgcaat ttctccagcg gttcctgcag atactgaagg ttttgtttcc    120

ttcttggtca tcacaaaatg ccttgatgtt cctgaccctt ttgtgcctga ccctactggg    180

gaccagcgca tcagccagga cgtggagcga ttctgccggc agctcagcag catggccagc    240

aagctcatca tctccccgtt caccctcgtc tactacactt accagtgctt ccaaagcaca    300

ggctggctcg ggcctgtgag catcttcggg tatttcatcc tggggaccgt ggtgaacaaa    360

actttgatgg gccccattgt gatgaagctg gtgcatcagg agaagctgga gggagatttt    420

aggtgtgtct ccctcacttg aggtttctgg gctggg                              456


<210>  8451
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  8451

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Gly Thr Ser Ala Ser Ala Arg Thr Trp Ser Asp Ser 
    50                  55                  60


Ala Gly Ser Ser Ala Ala Trp Pro Ala Ser Ser Ser Ser Pro Arg Ser 
65                  70                  75                  80


Pro Ser Ser Thr Thr Leu Thr Ser Ala Ser Lys Ala Gln Ala Gly Ser 
                85                  90                  95


Gly Leu 



<210>  8452
<211>  1351
<212>  DNA
<213>  Homo sapiens

<400>  8452
ctcggactct acccagtact gaactagggg cagctgggct ccagagtccc tcgggtctca     60

ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc aggcccaggt tagatctgca    120

atttctccag cggttcctgc agatactgaa ggttttgttt ccttcttggt catcacaaaa    180

tgccttgatg ttcctgaccc ttttgtgcct gaccctactg gctgaagagc tttgatcagt    240

tcacctgcaa cctgctgtat gtgagctgga ggaaggacct cactgagcac cttcaccgcc    300

tctacttccg gggccgtgcg tactacaccc tcaacgtgct gcgggatgac atcgataacc    360

cgtaggcgcc ccaactcagt cctttctaca ctctgtgtgg tcctttcctt ctggcctagc    420

cctggagact gctggtggca gacaccaagg agatcatctg cagtcgtttt caaatgctgc    480

tgcccagagt catgggggag ggtgccctgc agaggactcc tggagaagct gcagggctgt    540

gaataggcag ctaaaaagaa gaagcctgcc aggtgcagtg gcatgcacct gtagtcccaa    600

caactcagga ggctgaggca ggaggatcac ttgagcccag gagtagtgca ccgtgagcac    660

acttgggaat agccactgta ctctagcctg ggcaacatag cagaaacccc catctcttaa    720

aaaaaagaaa aatgttagga gcagctttct tttgtccttt tcatacttta tatcttagtc    780

ttccagtaag aagactaagg ggtttcttta gagggttcta aagaaaatgt ccttgctaga    840

aaaaccagct cttagatttt catcagtaaa aaaaattacc actatccagg actcagtcta    900

ggattcacat ctccattcta tcaccactca ggttataact cttaaagtca ccaagcccca    960

ggttcccctt ctgtaaaatg aggacaataa tagttcctat ctcaaagggt gtagtgagga   1020

tgaaatatca ttcatgtaat gcacatgtac agtgcttgac acatagcaag tgtttcagtg   1080

taagttagct attgttattt tacagatgag gaagctgaag cccagagatt gcaagtgact   1140

tgcccaaggt cacgtcactc attgggaata ggaatcagta tggccctagt ggtgagatga   1200

gacatagggg gtctccttca cacccatccc ctcactcacc accttcctag caagcacttt   1260

gttggttggg gtacctctca gctcaagctt agctttggtg caaagatgcg tgggaggctg   1320

ctgctgctgc ctaacttcta ggcctctttc t                                  1351


<210>  8453
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  8453

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Ala Glu Glu Leu 
    50                  55


<210>  8454
<211>  1490
<212>  DNA
<213>  Homo sapiens

<400>  8454
ccccgcccct cctcggactc tacccagtac tgaactaggg gcagctgggc tccagagtcc     60

ctcgggtctc aggtcatggc ggtcgcgggg cccgcgcccg gagctggcgc caggcccagg    120

ttagatctgc aatttctcca gcggttcctg cagatactga aggttttgtt tccttcttgg    180

tcatcacaaa atgccttgat gttcctgacc cttttgtgcc tgaccctact ggagcaattt    240

gtgatctacc aggttggctt gatccccagt cagtactatg gggtcctggg aaacaaagac    300

ttggaagggt ttaagactct gacattcctg gctgtcatgc tcattgttct gaactccacg    360

ctgaagagct ttgatcagtt cacctgcaac ctgctgtatg tgagctggag gaaggacctc    420

actgagcacc ttcaccgcct ctacttccgg ggccgtgcgt actacaccct caacgtgctg    480

cgggatgaca tcgataaccc gtaggcgccc caactcagtc ctttctacac tctgtgtggt    540

cctttccttc tggcctagcc ctggagactg ctggtggcag acaccaagga gatcatctgc    600

agtcgttttc aaatgctgct gcccagagtc atgggggagg gtgccctgca gaggactcct    660

ggagaagctg cagggctgtg aataggcagc taaaaagaag aagcctgcca ggtgcagtgg    720

catgcacctg tagtcccaac aactcaggag gctgaggcag gaggatcact tgagcccagg    780

agtagtgcac cgtgagcaca cttgggaata gccactgtac tctagcctgg gcaacatagc    840

agaaaccccc atctcttaaa aaaaagaaaa atgttaggag cagctttctt ttgtcctttt    900

catactttat atcttagtct tccagtaaga agactaaggg gtttctttag agggttctaa    960

agaaaatgtc cttgctagaa aaaccagctc ttagattttc atcagtaaaa aaaattacca   1020

ctatccagga ctcagtctag gattcacatc tccattctat caccactcag gttataactc   1080

ttaaagtcac caagccccag gttccccttc tgtaaaatga ggacaataat agttcctatc   1140

tcaaagggtg tagtgaggat gaaatatcat tcatgtaatg cacatgtaca gtgcttgaca   1200

catagcaagt gtttcagtgt aagttagcta ttgttatttt acagatgagg aagctgaagc   1260

ccagagattg caagtgactt gcccaaggtc acgtcactca ttgggaatag gaatcagtat   1320

ggccctagtg gtgagatgag acataggggg tctccttcac acccatcccc tcactcacca   1380

ccttcctagc aagcactttg ttggttgggg tacctctcag ctcaagctta gctttggtgc   1440

aaagatgcgt gggaggctgc tgctgctgcc taacttctag gcctctttct              1490


<210>  8455
<211>  142
<212>  PRT
<213>  Homo sapiens

<400>  8455

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Leu 
                85                  90                  95


Lys Ser Phe Asp Gln Phe Thr Cys Asn Leu Leu Tyr Val Ser Trp Arg 
            100                 105                 110


Lys Asp Leu Thr Glu His Leu His Arg Leu Tyr Phe Arg Gly Arg Ala 
        115                 120                 125


Tyr Tyr Thr Leu Asn Val Leu Arg Asp Asp Ile Asp Asn Pro 
    130                 135                 140


<210>  8456
<211>  730
<212>  DNA
<213>  Homo sapiens

<400>  8456
agccggggcc ccgcccctcc tcggactcta cccagtactg aactaggggc agctgggctc     60

cagagtccct cgggtctcag gtcatggcgg tcgcggggcc cgcgcccgga gctggcgcca    120

gagcaatttg tgatctacca ggttggcttg atccccagtc agtactatgg ggtcctggga    180

aacaaagact tggaagggtt taagactctg acattcctgg ctgtcatgct cattgttctg    240

aactccacgg taagatcttt ccctctctct gtgtctctcg tcctctccag tccagtgtga    300

ccgtaatgcc tagtggaact tagcctccag gaagcaggaa gcaagctgtg ggggtgtgtt    360

tcctcccttt tctgggaact aaagggatag ttgcctttat taagcacgtt gatcttgcta    420

ttggcccacg tgggactgat tcctcagatg tttccactcc tgggcccagg ccacaggttc    480

tggtttaatt cagcatttag cagaactgat cattgcccct ttccttccta gaactcttat    540

ttccggcagc tcattaaaac ggctcagcag ccagagctgc tgctcctcct ctgcgggacc    600

gaggctgtga ctcaccctgg caccatgtca cacctcccag cctttgaaca gtgctttctt    660

gcagaatggc ctcctcccct acccctcatt cagtaggggg gctaccacct gctcactctt    720

cgtcatccct                                                           730


<210>  8457
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  8457

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Ala Ile Cys 
1               5                   10                  15


Asp Leu Pro Gly Trp Leu Asp Pro Gln Ser Val Leu Trp Gly Pro Gly 
            20                  25                  30


Lys Gln Arg Leu Gly Arg Val 
        35


<210>  8458
<211>  719
<212>  DNA
<213>  Homo sapiens

<400>  8458
ctcggactct acccagtact gaactagggg cagctgggct ccagagtccc tcgggtctca     60

ggtcatggcg gtcgcggggc ccgcgcccgg agctggcgcc aggcccaggt tagatctgca    120

atttctccag cggttcctgc agatactgaa ggttttgttt ccttcttggt catcacaaaa    180

tgccttgatg ttcctgaccc ttttgtgcct gaccctactg gagcaatttg tgatctacca    240

ggttggcttg atccccagtc agtactatgg ggtcctggga aacaaagact tggaagggtt    300

taagactctg acattcctgg ctgtcatgct cattgttctg aactccacgg taagatcttt    360

ccctctctct gtgtctctcg tcctctccag tccagtgtga ccgtaatgcc tagtggaact    420

tagcctccag gaagcaggaa gcaagctgtg ggggtgtgtt tcctcccttt tctgggaact    480

aaagggatag ttgcctttat taagcacgtt gatcttgcta ttggcccacg tgggactgat    540

tcctcagatg tttccactcc tgggcccagg ccacaggttc tggtttaatt cagcatttag    600

cagaactgat cattgcccct ttccttccta gaactcttat ttccggcagc tcattaaaac    660

ggctcagcag ccagagctgc tgctcctcct ctgcgggacc gaggctgtga ctcaccctg     719


<210>  8459
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  8459

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Glu Gln Phe Val Ile Tyr Gln Val Gly Leu Ile Pro 
    50                  55                  60


Ser Gln Tyr Tyr Gly Val Leu Gly Asn Lys Asp Leu Glu Gly Phe Lys 
65                  70                  75                  80


Thr Leu Thr Phe Leu Ala Val Met Leu Ile Val Leu Asn Ser Thr Val 
                85                  90                  95


Arg Ser Phe Pro Leu Ser Val Ser Leu Val Leu Ser Ser Pro Val 
            100                 105                 110


<210>  8460
<211>  379
<212>  DNA
<213>  Homo sapiens

<400>  8460
gtagccgggg ccccgcccct cctcggactc tacccagtac tgaactaggg gcagctgggc     60

tccagagtcc ctcgggtctc aggtcatggc ggtcgcgggg cccgcgcccg gagctggcgc    120

caggcccagg ttagatctgc aatttctcca gcggttcctg cagatactga aggttttgtt    180

tccttcttgg tcatcacaaa atgccttgat gttcctgacc cttttgtgcc tgaccctact    240

gggctggagt gcagtgacat aatctcagct cactgcaacc tctgcctccc tggttcaagt    300

gattctcctg ccttcgcctc ctgagtagct gggattacaa gcacccacca ccacgcccga    360

ctaaactttg tatttttca                                                 379


<210>  8461
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  8461

Met Ala Val Ala Gly Pro Ala Pro Gly Ala Gly Ala Arg Pro Arg Leu 
1               5                   10                  15


Asp Leu Gln Phe Leu Gln Arg Phe Leu Gln Ile Leu Lys Val Leu Phe 
            20                  25                  30


Pro Ser Trp Ser Ser Gln Asn Ala Leu Met Phe Leu Thr Leu Leu Cys 
        35                  40                  45


Leu Thr Leu Leu Gly Trp Ser Ala Val Thr 
    50                  55


<210>  8462
<211>  521
<212>  DNA
<213>  Homo sapiens

<400>  8462
aaaagtacca gagagtggac tcggctgacc cggcggctac agcgccccca tattttctgg     60

gagacttccc ttttgacaat aggtatccga gagtgtaact actttatggt acgtttcctg    120

aggacagctg ctctgtgaag cccactgccc caaaggcacc tatcaaagac cctgcaaaca    180

agcagatggc aatccaggtt gccaatgaca ttgcccatcc caggtacctg ggctgcctgc    240

ttttccctga agtgggagcc tggcttgcag gatgacttct cggaaccagc tggtgcagaa    300

ggtgctgcag gagctgcagg aagcagtgga gtgcgaaggc ctggagggtc tcataggtgc    360

ttccttggag gccaagcagg tcctgtcttc cttcactctc cccacctgcc gggagggagg    420

ccctggcctc caggtgctgg aagtggactc ggtggccctg agcctgtatc cagaagatgc    480

tccacggaac atgctgccgc tggtgtgcaa gggggagggc a                        521


<210>  8463
<211>  104
<212>  PRT
<213>  Homo sapiens

<400>  8463

Met Thr Leu Pro Ile Pro Gly Thr Trp Ala Ala Cys Phe Ser Leu Lys 
1               5                   10                  15


Trp Glu Pro Gly Leu Gln Asp Asp Phe Ser Glu Pro Ala Gly Ala Glu 
            20                  25                  30


Gly Ala Ala Gly Ala Ala Gly Ser Ser Gly Val Arg Arg Pro Gly Gly 
        35                  40                  45


Ser His Arg Cys Phe Leu Gly Gly Gln Ala Gly Pro Val Phe Leu His 
    50                  55                  60


Ser Pro His Leu Pro Gly Gly Arg Pro Trp Pro Pro Gly Ala Gly Ser 
65                  70                  75                  80


Gly Leu Gly Gly Pro Glu Pro Val Ser Arg Arg Cys Ser Thr Glu His 
                85                  90                  95


Ala Ala Ala Gly Val Gln Gly Gly 
            100


<210>  8464
<211>  3465
<212>  DNA
<213>  Homo sapiens

<400>  8464
gcacttgagg gtgggcgatt tcctgggggg agtggcttaa gccgcttccc caccggccag     60

ttggctgtag acggtccatg ctcaatggtc ctctacagat atgaaactgg ttctggagtg    120

agacgagctc ggctggggac gctacttgag aaggcctttc cccacagggt gacttaaatg    180

tcccaggctg gaaggtggag cgagaagtgg atgcccccag ggctctgggt cacactccag    240

gatgacttct cggaaccagc tggtgcagaa ggtgctgcag gagctgcagg aagcagtgga    300

gtgcgaaggc ctggagggtc tcataggtgc ttccttggag gccaagcagg tcctgtcttc    360

cttcactctc cccacctgcc gggagggagg ccctggcctc caggtgctgg aagtggactc    420

ggtggccctg agcctgtatc cagaagatgc tccacggaac atgctgccgc tggtgtgcaa    480

gggggagggc agcctgctgt tcgaggcggc cagcatgctg ctgtggggtg acgcaggcct    540

cagcctggag ctgcgggccc gcaccgtggt agagatgctg ctgcacagac actactacct    600

ccagggcatg atcgactcca aagtgatgct gcaggccgtg cgctactccc tatgctctga    660

ggagtcccct gagatgacca gcttgccccc cgccacgctg gaggccatct tcgatgccga    720

cgtcaaggcc tcctgtttcc ccagcagctt ctccaacgtg tggcacttgt atgctctcgc    780

ctctgtcctc cagcggaaca tctactccat ctaccccatg cgcaacctca agatccggcc    840

ctacttcaac cgtgtcatcc ggccccgccg ctgcgaccac gtgccctcca cgctgcacat    900

catgtgggct ggccagcccc tcaccagcca cttcttccgc caccagtact ttgcccctgt    960

ggtggggctg gaagaggtgg aggctgaagg tgcccctggc gtggccccag ctcttccagc   1020

cctggcccca ctctcatcgc cggccaagac cctggagctg ctcaaccgtg aacctggcct   1080

cagctactct cacctctgtg agcgctacag cgtcaccaaa agcaccttct accgctggcg   1140

gcggcagtcc caggagcacc ggcagaaggt tgctgcccgc ttctccgcca agcacttcct   1200

gcaggacagc ttccaccggg ggggcgtcgt gccacttcag cagttcctcc agcggttccc   1260

ggagatctcc cgctcaacct actatgcctg gaagcatgag ctgctgggct ctggcacctg   1320

cccggccttg ccccccaggg aggtgctggg catggaggag ctagagaagc tgccggagga   1380

gcaggtggct gaggaggagc tggagtgctc cgcactggcg gtgtcaagcc ctggaatggt   1440

cttaatgcag cgggccaagt tgtacctgga gcattgcatc tccctgaaca cactggtacc   1500

ctatcgctgc ttcaaacgca ggttccctgg catctcacgg tccacttatt ataattggcg   1560

gcgaaaggcc ctccggagga accccagctt caagccggca ccagccctct ctgctgctgg   1620

gactccccag ctagcatctg ttggggaagg ggctgtaatt ccttggaaga gtgaggcgga   1680

agagggggca gggaatgcca caggtgagga ccctcccgcc cccggggagc tcctgccact   1740

aaggatgccc ctgtcccgtt ggcagaggcg tctgcgcagg gctgcccgca ggcaggtgct   1800

gagtgggcat ctccctttct gccgcttccg cctccgctac cccagcctgt caccttctgc   1860

cttttgggtc tggaagagtc ttgctcgggg ttggcccaga ggcctgtcca aacttcaggt   1920

gccggtcccc accttgggca aaggggggca ggaggctgag gagaagcagg agaaggaggc   1980

tggcagggat gtgacagctg tgatggcccc acctgtgggg gcttcttcag aagatgtaga   2040

gggagggcct tccagagagg gggccctgca ggagggggcc acagcccagg gccagcccca   2100

cagtgggccc ttgctgagcc aacctgtggt ggcagcagcg ggtggcaggg atggccggat   2160

gctggtgatg gacatgatcg ctaccacgaa gttcaaggcc caggccaagc tgttcttgca   2220

gaagcgcttc cagtccaaga gctttccctc ctacaaggag ttcagtgccc tctttcccct   2280

cactgcccgc tccacatact acatgtggaa gcgagccctc tatgacggcc tgaccctggt   2340

agatggctga cagggaggta caaaaggggc tgggaagaag ggggaccagt ttggagaggg   2400

tcagggacct gagctgaccc caggcttggc caggatgtcc tttgctctgg gtcccacagt   2460

gtctacccta agtccaaggg tatatttgtg ttattttctg gctccaggac agagaatgcc   2520

agaaatcagc catctggtct cccgtaggaa actgtgggac cagagatatc ctctttcgtt   2580

gtttgctggt catattttta ctgttatgat ttagtttttg gttttgattt gagtgggttg   2640

gttggccccc ttgctggagt tggaagccgt atgtatgtca gggggtttag aggggggttg   2700

gttagctaga gctgctttca gcttttcctg gagacaaaag gagtgttata gcatgatcat   2760

cggtcccact gggcagaacg ttatcttcag tttcttttgg gggttggcat cctctttact   2820

cagttgtttc ccaaaggaac attaggctcg aatatggggg ccaggtgtgg tggcttatgc   2880

ctgtaatcct agcgctttgg gaggccaagg caggaggatc acttgaggct aggagttaga   2940

gaccaccctg ggcaatgtag tgagacctca tctcttagaa aaaaaaaaag aaagaaaatc   3000

aaatgtagag ctgatcagca gcttgtgcct ggcatcccca agggagaagg tgccaggtca   3060

gcaggagcag cagcagggat gtatagaaag aaccacagct ggcctctaaa ggatggcact   3120

gaggcaccgg agatcttgag gcactggaga tcactgaggg gctggcctgt cccctgcaag   3180

gagtgtggga ccaggtgggg caaggctggg agatgcaggc tctgtttgca gattatggcc   3240

cagagtctct gcttgtgggt gcttgatcca cctgctggga ccctgcagtc ctcggccagc   3300

ctggctgtca gttggggatt ccacctttct gctgagcgtc ttctcggagc tggaggccca   3360

tcttcagtga gagatcacaa agcggccagg caggtgggag actgaatttg ccttgttcga   3420

gagtaacgtt tgaaaaccaa agaaataaag tgatgcagtg cccac                   3465


<210>  8465
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  8465

Met Ser Gln Ala Gly Arg Trp Ser Glu Lys Trp Met Pro Pro Gly Leu 
1               5                   10                  15


Trp Val Thr Leu Gln Asp Asp Phe Ser Glu Pro Ala Gly Ala Glu Gly 
            20                  25                  30


Ala Ala Gly Ala Ala Gly Ser Ser Gly Val Arg Arg Pro Gly Gly Ser 
        35                  40                  45


His Arg Cys Phe Leu Gly Gly Gln Ala Gly Pro Val Phe Leu His Ser 
    50                  55                  60


Pro His Leu Pro Gly Gly Arg Pro Trp Pro Pro Gly Ala Gly Ser Gly 
65                  70                  75                  80


Leu Gly Gly Pro Glu Pro Val Ser Arg Arg Cys Ser Thr Glu His Ala 
                85                  90                  95


Ala Ala Gly Val Gln Gly Gly Gly Gln Pro Ala Val Arg Gly Gly Gln 
            100                 105                 110


His Ala Ala Val Gly 
        115


<210>  8466
<211>  464
<212>  DNA
<213>  Homo sapiens

<400>  8466
attcagtgat agtggcggtg gataacaatg acctcctacc agctgtgaat ttctcgtctt     60

ccactagtac tagtaaaaga gattgctgct ggctaagaat acccaccggt ggggtcttga    120

gccttggagg agcctccctc ggggtcagga atcgagcggg gacaccgctg ggccactcag    180

aaggaccgtt tcctggggac tgatcaagag gagggaaggt cctattacag cccagaggcc    240

acgtggggcc tgagccccaa acctcagctg ctgttccagc agccccgtag ctgggtggag    300

cctccgggcc tgacgtggac cttcactgga gaagtgactc aggtgggaaa agtctccccg    360

ggcctctcca cctgcaggat cgccttccta caccttcccc cgcccgcttc cttcgcgcgg    420

gctcctccca atgaccacca gcagaactgc agcctcctgc ctta                     464


<210>  8467
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  8467

Ala Leu Glu Glu Pro Pro Ser Gly Ser Gly Ile Glu Arg Gly His Arg 
1               5                   10                  15


Trp Ala Thr Gln Lys Asp Arg Phe Leu Gly Thr Asp Gln Glu Glu Gly 
            20                  25                  30


Arg Ser Tyr Tyr Ser Pro Glu Ala Thr Trp Gly Leu Ser Pro Lys Pro 
        35                  40                  45


Gln Leu Leu Phe Gln Gln Pro Arg Ser Trp Val Glu Pro Pro Gly Leu 
    50                  55                  60


Thr Trp Thr Phe Thr Gly Glu Val Thr Gln Val Gly Lys Val Ser Pro 
65                  70                  75                  80


Gly Leu Ser Thr Cys Arg Ile Ala Phe Leu His Leu Pro Pro Pro Ala 
                85                  90                  95


Ser Phe Ala Arg Ala Pro Pro Asn Asp His Gln Gln Asn Cys Ser Leu 
            100                 105                 110


Leu 



<210>  8468
<211>  5334
<212>  DNA
<213>  Homo sapiens

<400>  8468
ctgtcactgc agcctggcgg cctgagcgcc gagcctgggg ctggggccgc ggtgctgagg     60

acgcaaatca gccccgtagc tgggtggagc ctccgggcct gacgtggacc ttcactggag    120

aagtgactca gggatcctcc caggatgtct gcctcaccag acgacctgag tacaggggga    180

aggttacaga acatgacagt ggatgaatgc ttccagtctc ggaacaccgt cctccagggg    240

cagccctttg ggggtgtccc caccgtgctg tgcctcaaca tcgccctgtg ggtgctcgtc    300

cttgtggttt actccttcct ccggaaagct gcgtgggact atgggcgcct ggctctgctg    360

atacacaatg acagcctgac ctcgctgatc tatggggagc agagcgagaa gacatctccc    420

tcggagactt ccttggagat ggaacgcaga gacaagggat tctgttcctg gttcttcaac    480

agcataacaa tgaaggacga ggatctgatt aacaagtgtg gggacgacgc acgcatctac    540

atcgtgttcc agtaccacct catcatcttt gtgctcatca tctgtatccc ctccctgggc    600

atcattttgc ccatcaacta tactggatct gttctggact ggagcagtca ctttgctcgg    660

accaccattg tcaatgtctc cacagagagc aagctcctgt ggctgcatag cctgctgtcc    720

ttcttctact tcatcaccaa cttcatgttc atggctcatc actgcctggg gtttgcaccc    780

aggaatagcc aaaaggtcac aaggacacta atgatcacct atgtgcccaa ggacattgaa    840

gacccagaac tcatcattaa gcattttcac gaggcctatc caggcagtgt cgtgacaaga    900

gtccacttct gctacgacgt caggaacctg atcgacttgg acgatcagag gcgccatgcc    960

atgcggggcc ggcttttcta tacagccaag gccaagaaga ctgggaaggt gatgatcagg   1020

atccacccct gtgcccgcct gtgcttctgc aagtgctgga cctgcttcaa ggaggtggat   1080

gcagagcagt attacagcga gctagaggag cagctaacgg acgagttcaa cgccgagctc   1140

aaccgcgtgc cgctcaagcg gctggacctg atctttgtca ccttccagga ctccaggatg   1200

gccaagcgtg tccgtaagga ttacaagtat gtccagtgtg gtgtgcaacc ccagcagtcc   1260

tcagtgacca ccatcgtcaa atcatattac tggagggtca ctatggcccc acaccccaaa   1320

gacattattt ggaaacacct gtctgtccgc cgcttctttt ggtgggcccg ctttatcgca   1380

atcaacacct tcctcttctt cctcttcttc tttctcacca cgcctgccat catcatgaac   1440

actatcgaca tgtacaacgt cacccgcccc atcgagaagc tgcagaaccc aattgtgacc   1500

cagttcttcc cctctgtgat gctctggggc ttcacagtga tactgcctct gattgtctac   1560

ttctccgcct tcctcgaggc ccactggacc agatcaagtc agaatctggt catggtgcac   1620

aagtgctaca tctttctggt gttcatggta gtcattctgc cctctatggg actgaccagt   1680

ttggatgtct ttctccgctg gctctttgac atctactatc tagagcaagc atccatcagg   1740

ttccagtgtg tgttcctgcc agacaacggc gccttctttg tcaactacgt gatcacggca   1800

gctttacttg gcacaggcat ggagctgctg cgtctggggt cactcttctg ctacagcacc   1860

cgcctcttct tctctagatc agagccagag agagtcaaca tcagaaagaa ccaggccata   1920

gacttccagt ttgggcgtga gtatgcgtgg atgatgaacg tgttcagcgt ggtgatggcg   1980

tacagcatca cttgccccat cattgtgcct tttgggttgc tctacctgtg catgaagcac   2040

ttgacggatc gctataacat gtactactcc tttgcaccca ccaaactgaa cgagcagatc   2100

cacatggctg ccgtctccca ggccatcttt gcgccactct tgggtctgtt ctggatgctg   2160

ttcttctcca tcctgcggtt gggttctctc cacgccatca ccatcttttc cctgtccacc   2220

ctcctcattg ccatggtgat tgcctttgtt ggcatttttc tggggaagct tcggatggtt   2280

gccgactacg agcccgagga ggaggagatc cagacagtgt ttgacatgga gccaagcagc   2340

acctcctcca cgcccacctc cctcctgtat gtggccaccg tgctgcaaga accggagttg   2400

aatctgaccc ccgcctcctc cccagccagg cacacctatg gcaccatgaa caaccagccg   2460

gaagagggag aagaagagag tggtctgagg ggctttgcga gggagctaga ctcggcccag   2520

ttccaggaag ggctggaact ggagggccag aaccagtacc actgaccggg acctgaggcc   2580

tccactggcg acttgttgag gggtcagggg agggcctggc aaggggaggc aggagggtgg   2640

cctggacctc cccactacct cctgcagact ttgagaagcc cacagtggag acatccacca   2700

ccccagccat gggccatacg ggggtcctga cctgctgccc ggctggaact gggggtgctc   2760

ggcagtgctg aaggagcctg ggaagggatg ggaggataca ggcaagcaca tgtcttgaga   2820

gaggtggctg gagccccggc acagagactg aacgctgggg tcccttcctg ggaccaagat   2880

ggagaaggtg ttcctaaggg aggagacaga aggaggctgc cgaaggctct gtggggtcat   2940

caccactctg catcagctgc ccttccaagg agcttctgct gctgctcctc ctcccagccc   3000

cggcccattc ctcccctgca gtctgaggag gcaaaggtat gtgcacgggg cacattgaca   3060

ggacacggag gaccacctca tcacagggtt ccctgcatgg ggatctgtaa agagaaagtt   3120

tctgcaccca ccagagcaag agccaactga aagcgtagac ctgagaagag gtaactcagc   3180

cccttcctgc tcctctgccc tcatcagatg tccccaggag cagcagggca gaggcccttc   3240

tttctattct tacaagggta gctagagcgt gatcactcag ggctcatcaa atgagactcg   3300

tgtgcatttt tcagaaggaa accttggtta gtccttgctg ggtaacacaa agtggggtga   3360

gacgacagaa gccgaattca tggaaggggg gtcttctccc caaaactctg tgtggtggga   3420

aaccagctat acctccccaa gccccagggc ctaaagagaa gacccccgaa gccaaagatg   3480

tggccactta aaagcgtctc ctgcctccta cccaactgag tgcctgggcc cccagcttgg   3540

ccaagatggg cagtacgtta gggtaagaac cccatgcttc aaacttaagg actgaccatc   3600

acctgcgtcc caagtaggac ccttcctccc ttctcggggc tgcccctgca ccctgccttg   3660

aagaccaccc aagcggcctc cagtgtgggc ctggtccaga cattgcagat gcttcaaccg   3720

tgatgtcgcc ccaggcctgc caggggtgtg gtggagggga aggccacgtg ctccagggag   3780

aagccctttc tggagaagca aggctgtcct cccagggctg ccactaccag agacctgggg   3840

gagctgaatt ccgaacagtg atggtgacac tcagcacctt tgccacagcc ggggggaacc   3900

ggcttctgcc tctgggatgg gctctcatca ggaccaccgt gcagcccagc cagggaggac   3960

atgagaaggg ccagtggggg cctcaatgaa ccagaacaag ccaagctgaa tggggtctgt   4020

gtgctccagg gccctcttca gccccctccc ccaaaggtct gggtccctgc caccaaccta   4080

ctgaaggccg gcccccggct cacctcacct gagcacctgc accaggcccc aggcacatgg   4140

ctgccctgaa ctcagatcac ctagaccttg tccctgcccc acctttgccc catcctagcc   4200

ccagaagctc caagcttcac cgcaggtgag aaattgtgct caatgggcag aaactgctat   4260

acccccaggg catggcccac attttggcat gagggtgtct ttccagagag cttgggttgg   4320

ctggagagag gctgtctttc ccattccttg tccagctagg aataaagggg aaatggtcct   4380

agcctggccc ctacacaccc aggtcccaca ggccccctcc ccactggaat ttcaccaacc   4440

aacaagggga aagtacgctg ttacagcata gcggtcaggc ccagcaggag cttggcacat   4500

gatggggagg tggccagctc caggccctgc ccgaccccat catgtgtatt tggtgtatgg   4560

ggtgtggggg gtcacaccag aagctggcct ggggtctctt ctttgctgga cacagctccc   4620

tggcccctgc ccccagcccc tgcagcccct gccggactgt ggaagccaca tatgggaaaa   4680

gtcctggcag acaatgtggc gggatgactg ggggcttctc cctctgaacc tgggtccagt   4740

gtagcctggc tctgagagaa ggtggtgagc atgtggagaa ggttccatag tccactctta   4800

ggggaaccag caaagcctca tggcagttgg ctccatctgg acctcccatg gtcactacag   4860

gatggtggag cagggggcat cttttagcct ccccccgcca ccacatccag gccctctcag   4920

gcacctcctg cctcagccca cacctgcctc acccattgcc cccctccccc cacctactgc   4980

catcccactc ctctgccagc cacttcccag ccgccccacc ccactccatc caccaaatca   5040

cctcctgact taatcctttc tggaaggagc tgccgcccag gaaccggtat tgcctagagc   5100

ctccaggagg ggccctcctc aggcctccag tggccccatg cccacctgcc tgaccctcca   5160

ctgcccctgg aagcaaagtg cctatcagca gcgttgcgtc ctctggggcc cccggtcggg   5220

ggggaggggg tgtgggctaa ccttggccac caccacaaaa ggaatgtgcc agaatgctga   5280

accttcttgt taatgctatg accgtgcctt gaataaacaa gtcctcccaa cctc         5334


<210>  8469
<211>  806
<212>  PRT
<213>  Homo sapiens

<400>  8469

Met Ser Ala Ser Pro Asp Asp Leu Ser Thr Gly Gly Arg Leu Gln Asn 
1               5                   10                  15


Met Thr Val Asp Glu Cys Phe Gln Ser Arg Asn Thr Val Leu Gln Gly 
            20                  25                  30


Gln Pro Phe Gly Gly Val Pro Thr Val Leu Cys Leu Asn Ile Ala Leu 
        35                  40                  45


Trp Val Leu Val Leu Val Val Tyr Ser Phe Leu Arg Lys Ala Ala Trp 
    50                  55                  60


Asp Tyr Gly Arg Leu Ala Leu Leu Ile His Asn Asp Ser Leu Thr Ser 
65                  70                  75                  80


Leu Ile Tyr Gly Glu Gln Ser Glu Lys Thr Ser Pro Ser Glu Thr Ser 
                85                  90                  95


Leu Glu Met Glu Arg Arg Asp Lys Gly Phe Cys Ser Trp Phe Phe Asn 
            100                 105                 110


Ser Ile Thr Met Lys Asp Glu Asp Leu Ile Asn Lys Cys Gly Asp Asp 
        115                 120                 125


Ala Arg Ile Tyr Ile Val Phe Gln Tyr His Leu Ile Ile Phe Val Leu 
    130                 135                 140


Ile Ile Cys Ile Pro Ser Leu Gly Ile Ile Leu Pro Ile Asn Tyr Thr 
145                 150                 155                 160


Gly Ser Val Leu Asp Trp Ser Ser His Phe Ala Arg Thr Thr Ile Val 
                165                 170                 175


Asn Val Ser Thr Glu Ser Lys Leu Leu Trp Leu His Ser Leu Leu Ser 
            180                 185                 190


Phe Phe Tyr Phe Ile Thr Asn Phe Met Phe Met Ala His His Cys Leu 
        195                 200                 205


Gly Phe Ala Pro Arg Asn Ser Gln Lys Val Thr Arg Thr Leu Met Ile 
    210                 215                 220


Thr Tyr Val Pro Lys Asp Ile Glu Asp Pro Glu Leu Ile Ile Lys His 
225                 230                 235                 240


Phe His Glu Ala Tyr Pro Gly Ser Val Val Thr Arg Val His Phe Cys 
                245                 250                 255


Tyr Asp Val Arg Asn Leu Ile Asp Leu Asp Asp Gln Arg Arg His Ala 
            260                 265                 270


Met Arg Gly Arg Leu Phe Tyr Thr Ala Lys Ala Lys Lys Thr Gly Lys 
        275                 280                 285


Val Met Ile Arg Ile His Pro Cys Ala Arg Leu Cys Phe Cys Lys Cys 
    290                 295                 300


Trp Thr Cys Phe Lys Glu Val Asp Ala Glu Gln Tyr Tyr Ser Glu Leu 
305                 310                 315                 320


Glu Glu Gln Leu Thr Asp Glu Phe Asn Ala Glu Leu Asn Arg Val Pro 
                325                 330                 335


Leu Lys Arg Leu Asp Leu Ile Phe Val Thr Phe Gln Asp Ser Arg Met 
            340                 345                 350


Ala Lys Arg Val Arg Lys Asp Tyr Lys Tyr Val Gln Cys Gly Val Gln 
        355                 360                 365


Pro Gln Gln Ser Ser Val Thr Thr Ile Val Lys Ser Tyr Tyr Trp Arg 
    370                 375                 380


Val Thr Met Ala Pro His Pro Lys Asp Ile Ile Trp Lys His Leu Ser 
385                 390                 395                 400


Val Arg Arg Phe Phe Trp Trp Ala Arg Phe Ile Ala Ile Asn Thr Phe 
                405                 410                 415


Leu Phe Phe Leu Phe Phe Phe Leu Thr Thr Pro Ala Ile Ile Met Asn 
            420                 425                 430


Thr Ile Asp Met Tyr Asn Val Thr Arg Pro Ile Glu Lys Leu Gln Asn 
        435                 440                 445


Pro Ile Val Thr Gln Phe Phe Pro Ser Val Met Leu Trp Gly Phe Thr 
    450                 455                 460


Val Ile Leu Pro Leu Ile Val Tyr Phe Ser Ala Phe Leu Glu Ala His 
465                 470                 475                 480


Trp Thr Arg Ser Ser Gln Asn Leu Val Met Val His Lys Cys Tyr Ile 
                485                 490                 495


Phe Leu Val Phe Met Val Val Ile Leu Pro Ser Met Gly Leu Thr Ser 
            500                 505                 510


Leu Asp Val Phe Leu Arg Trp Leu Phe Asp Ile Tyr Tyr Leu Glu Gln 
        515                 520                 525


Ala Ser Ile Arg Phe Gln Cys Val Phe Leu Pro Asp Asn Gly Ala Phe 
    530                 535                 540


Phe Val Asn Tyr Val Ile Thr Ala Ala Leu Leu Gly Thr Gly Met Glu 
545                 550                 555                 560


Leu Leu Arg Leu Gly Ser Leu Phe Cys Tyr Ser Thr Arg Leu Phe Phe 
                565                 570                 575


Ser Arg Ser Glu Pro Glu Arg Val Asn Ile Arg Lys Asn Gln Ala Ile 
            580                 585                 590


Asp Phe Gln Phe Gly Arg Glu Tyr Ala Trp Met Met Asn Val Phe Ser 
        595                 600                 605


Val Val Met Ala Tyr Ser Ile Thr Cys Pro Ile Ile Val Pro Phe Gly 
    610                 615                 620


Leu Leu Tyr Leu Cys Met Lys His Leu Thr Asp Arg Tyr Asn Met Tyr 
625                 630                 635                 640


Tyr Ser Phe Ala Pro Thr Lys Leu Asn Glu Gln Ile His Met Ala Ala 
                645                 650                 655


Val Ser Gln Ala Ile Phe Ala Pro Leu Leu Gly Leu Phe Trp Met Leu 
            660                 665                 670


Phe Phe Ser Ile Leu Arg Leu Gly Ser Leu His Ala Ile Thr Ile Phe 
        675                 680                 685


Ser Leu Ser Thr Leu Leu Ile Ala Met Val Ile Ala Phe Val Gly Ile 
    690                 695                 700


Phe Leu Gly Lys Leu Arg Met Val Ala Asp Tyr Glu Pro Glu Glu Glu 
705                 710                 715                 720


Glu Ile Gln Thr Val Phe Asp Met Glu Pro Ser Ser Thr Ser Ser Thr 
                725                 730                 735


Pro Thr Ser Leu Leu Tyr Val Ala Thr Val Leu Gln Glu Pro Glu Leu 
            740                 745                 750


Asn Leu Thr Pro Ala Ser Ser Pro Ala Arg His Thr Tyr Gly Thr Met 
        755                 760                 765


Asn Asn Gln Pro Glu Glu Gly Glu Glu Glu Ser Gly Leu Arg Gly Phe 
    770                 775                 780


Ala Arg Glu Leu Asp Ser Ala Gln Phe Gln Glu Gly Leu Glu Leu Glu 
785                 790                 795                 800


Gly Gln Asn Gln Tyr His 
                805


<210>  8470
<211>  3232
<212>  DNA
<213>  Homo sapiens

<400>  8470
gacggtccct ggcatctgcc agttggggtg gcatctcggc tggcagactc ctgcccatga     60

ctttttctcc tcctcggcag gttctctcca cgccatcacc atcttttccc tgtccaccct    120

cctcattgcc atggtgattg cctttgttgg catttttctg gggaagcttc ggatggttgc    180

cgactacgag cccgaggagg aggagatcca gacagtgttt gacatggagc caagcagcac    240

ctcctccacg cccacctccc tcctgtatgt ggccaccgtg ctgcaagaac cggagttgaa    300

tctgaccccc gcctcctccc cagccaggca cacctatggc accatgaaca accagccgga    360

agagggagaa gaagagagtg gtctgagggg ctttgcgagg gagctagact cggcccagtt    420

ccaggaaggg ctggaactgg agggccagaa ccagtaccac tgaccgggac ctgaggcctc    480

cactggcgac ttgttgaggg gtcaggggag ggcctggcaa ggggaggcag gagggtggcc    540

tggacctccc cactacctcc tgcagacttt gagaagccca cagtggagac atccaccacc    600

ccagccatgg gccatacggg ggtcctgacc tgctgcccgg ctggaactgg gggtgctcgg    660

cagtgctgaa ggagcctggg aagggatggg aggatacagg caagcacatg tcttgagaga    720

ggtggctgga gccccggcac agagactgaa cgctggggtc ccttcctggg accaagatgg    780

agaaggtgtt cctaagggag gagacagaag gaggctgccg aaggctctgt ggggtcatca    840

ccactctgca tcagctgccc ttccaaggag cttctgctgc tgctcctcct cccagccccg    900

gcccattcct cccctgcagt ctgaggaggc aaaggtatgt gcacggggca cattgacagg    960

acacggagga ccacctcatc acagggttcc ctgcatgggg atctgtaaag agaaagtttc   1020

tgcacccacc agagcaagag ccaactgaaa gcgtagacct gagaagaggt aactcagccc   1080

cttcctgctc ctctgccctc atcagatgtc cccaggagca gcagggcaga ggcccttctt   1140

tctattctta caagggtagc tagagcgtga tcactcaggg ctcatcaaat gagactcgtg   1200

tgcatttttc agaaggaaac cttggttagt ccttgctggg taacacaaag tggggtgaga   1260

cgacagaagc cgaattcatg gaaggggggt cttctcccca aaactctgtg tggtgggaaa   1320

ccagctatac ctccccaagc cccagggcct aaagagaaga cccccgaagc caaagatgtg   1380

gccacttaaa agcgtctcct gcctcctacc caactgagtg cctgggcccc cagcttggcc   1440

aagatgggca gtacgttagg gtaagaaccc catgcttcaa acttaaggac tgaccatcac   1500

ctgcgtccca agtaggaccc ttcctccctt ctcggggctg cccctgcacc ctgccttgaa   1560

gaccacccaa gcggcctcca gtgtgggcct ggtccagaca ttgcagatgc ttcaaccgtg   1620

atgtcgcccc aggcctgcca ggggtgtggt ggaggggaag gccacgtgct ccagggagaa   1680

gccctttctg gagaagcaag gctgtcctcc cagggctgcc actaccagag acctggggga   1740

gctgaattcc gaacagtgat ggtgacactc agcacctttg ccacagccgg ggggaaccgg   1800

cttctgcctc tgggatgggc tctcatcagg accaccgtgc agcccagcca gggaggacat   1860

gagaagggcc agtgggggcc tcaatgaacc agaacaagcc aagctgaatg gggtctgtgt   1920

gctccagggc cctcttcagc cccctccccc aaaggtctgg gtccctgcca ccaacctact   1980

gaaggccggc ccccggctca cctcacctga gcacctgcac caggccccag gcacatggct   2040

gccctgaact cagatcacct agaccttgtc cctgccccac ctttgcccca tcctagcccc   2100

agaagctcca agcttcaccg caggtgagaa attgtgctca atgggcagaa actgctatac   2160

ccccagggca tggcccacat tttggcatga gggtgtcttt ccagagagct tgggttggct   2220

ggagagaggc tgtctttccc attccttgtc cagctaggaa taaaggggaa atggtcctag   2280

cctggcccct acacacccag gtcccacagg ccccctcccc actggaattt caccaaccaa   2340

caaggggaaa gtacgctgtt acagcatagc ggtcaggccc agcaggagct tggcacatga   2400

tggggaggtg gccagctcca ggccctgccc gaccccatca tgtgtatttg gtgtatgggg   2460

tgtggggggt cacaccagaa gctggcctgg ggtctcttct ttgctggaca cagctccctg   2520

gcccctgccc ccagcccctg cagcccctgc cggactgtgg aagccacata tgggaaaagt   2580

cctggcagac aatgtggcgg gatgactggg ggcttctccc tctgaacctg ggtccagtgt   2640

agcctggctc tgagagaagg tggtgagcat gtggagaagg ttccatagtc cactcttagg   2700

ggaaccagca aagcctcatg gcagttggct ccatctggac ctcccatggt cactacagga   2760

tggtggagca gggggcatct tttagcctcc ccccgccacc acatccaggc cctctcaggc   2820

acctcctgcc tcagcccaca cctgcctcac ccattgcccc cctcccccca cctactgcca   2880

tcccactcct ctgccagcca cttcccagcc gccccacccc actccatcca ccaaatcacc   2940

tcctgactta atcctttctg gaaggagctg ccgcccagga accggtattg cctagagcct   3000

ccaggagggg ccctcctcag gcctccagtg gccccatgcc cacctgcctg accctccact   3060

gcccctggaa gcaaagtgcc tatcagcagc gttgcgtcct ctggggcccc cggtcggggg   3120

ggagggggtg tgggctaacc ttggccacca ccacaaaagg aatgtgccag aatgctgaac   3180

cttcttgtta atgctatgac cgtgccttga ataaacaagt cctcccaacc tc           3232


<210>  8471
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  8471

Met Val Ile Ala Phe Val Gly Ile Phe Leu Gly Lys Leu Arg Met Val 
1               5                   10                  15


Ala Asp Tyr Glu Pro Glu Glu Glu Glu Ile Gln Thr Val Phe Asp Met 
            20                  25                  30


Glu Pro Ser Ser Thr Ser Ser Thr Pro Thr Ser Leu Leu Tyr Val Ala 
        35                  40                  45


Thr Val Leu Gln Glu Pro Glu Leu Asn Leu Thr Pro Ala Ser Ser Pro 
    50                  55                  60


Ala Arg His Thr Tyr Gly Thr Met Asn Asn Gln Pro Glu Glu Gly Glu 
65                  70                  75                  80


Glu Glu Ser Gly Leu Arg Gly Phe Ala Arg Glu Leu Asp Ser Ala Gln 
                85                  90                  95


Phe Gln Glu Gly Leu Glu Leu Glu Gly Gln Asn Gln Tyr His 
            100                 105                 110


<210>  8472
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  8472
acatgttcta aaggagcagt ggactaggag tggggagtcc tgccactgaa ccagccctgg     60

gagcacctag atgctcatca aatgatcaag aacaattagg tgggtgggac agacaggacc    120

caggctgctg gggaagaagg caggctccaa ggtctggagg agacagaggc gatgggggtg    180

gggcatgagg ggagagggtg tgcccagggc cttgccccca acgtgacctt gctcctgtcc    240

cctgtctcta tcccaagcag ctgtatgtgg ccaccgtgct gcaagaaccg gagttgaatc    300

tgacccccgc ctcctcccca gccaggcaca cctatggcac catgaacaac cagccggaag    360

agggagaaga agagagtgtg cctatcagca gcgttgcgtc ctctggggcc cccggtcggg    420

ggggaggggg tgtgggctaa ccttggccac caccacaaaa ggaatgtgcc agaatgctga    480

accttcttgt taatgctatg accgtgcctt gaataaacaa gtcctcccaa cctctcctgg    540


<210>  8473
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  8473

Met Asn Asn Gln Pro Glu Glu Gly Glu Glu Glu Ser Val Pro Ile Ser 
1               5                   10                  15


Ser Val Ala Ser Ser Gly Ala Pro Gly Arg Gly Gly Gly Gly Val Gly 
            20                  25                  30


<210>  8474
<211>  1884
<212>  DNA
<213>  Homo sapiens

<400>  8474
ttcccaggcc accatagcgg ctggcggagg gagcgcgcgc cttgctggcc tggagggggc     60

gggggccgtg gcggctttaa agcgcccagc ccaggcgtcg cggggtgggg cggctctggc    120

ggctgcgggg cgcagggcgc agcggccaag cggggtcccc ggaagcacag ctggggtgtc    180

tccacctacg actggccgcg cgccttttct ctcccgcgcc agggaaggag cggctgcggc    240

ccccgccggg cggaggcacg gggggcgtac gaggggcgga ggggaccgcg tcgcggagga    300

gatggcgcgg cacgtgcggt gacggcaccc gagccctgag ggtcccagcc ccgcgctccg    360

cgtccccggg acagcatgga gcgcccggag cccgagctga tccggcagag ctggcgggca    420

gtgagccgca gcccgctgga gcacggcacc gtcctgtttg ccaggctgtt tgccctggag    480

cctgacctgc tgcccctctt ccagtacaac tgccgccagt tctccagccc agaggactgt    540

ctctcctcgc ctgagttcct ggaccacatc aggaaggtga tgctcgtgat tgatgctgca    600

gtgaccaatg tggaagacct gtcctcactg gaggagtacc ttgccagcct gggcaggaag    660

caccgggcag tgggtgtgaa gctcagctcc ttctcgacag tgggtgagtc tctgctctac    720

atgctggaga agtgtctggg ccctgccttc acaccagcca cacgggctgc ctggagccaa    780

ctctacgggg ccgtagtgca ggccatgagt cgaggctggg atggcgagta agaggcgacc    840

ccgcccggca gcccccatcc atctgtgtct gtctgttggc ctgtatctgt tgtagcccag    900

gctccccaag cttccctgca tcttggtcct tgtccccttg gccacactgg agaggtgatg    960

gggcagggct gggtctcagt atcctagagt ccagctgcag aaggagtggc ttttcctcca   1020

ggaaggggct tctgggtgtc ccctcatccc cagtagcctc tttcttgcgt ttctttttac   1080

cttttttggc actccctctg accccgcgat gagtgttttg gtggcagagg tgggatgagc   1140

tggaaaggta tggaggtggg agaggatggg gctcttctgt ctgtcctgct tcttcaggtg   1200

agtgcaggcc aaggcggggg tgagatggct gagcttccag cgccttctgt cctgcctgcc   1260

cagtcccttc actgctttcc tgccccaaga tggcttgctt ttcacaaata aagagaaaga   1320

gcagctttag ccttcttggt ggaatcccag gcagtgggag cagaatcaga actgccaggg   1380

aagggaaggg ggacctgggt ctcaatgggt ctcatttgag tctcgcgggc tgtgcagatg   1440

ccctgacaga gtcggtttcc tttggcggca ttccctttcc ctcattcagc acttctgctg   1500

ggaactccct gactattccg ctgctgcagg aacccagcta gctggccagg tggggagggg   1560

ctggggaccg gccaggaagg aggggtgact tcatcccaga gagacccgag ttcccccagc   1620

ccttcatcac caacccgctc ctgcaggagt gagtcttacc tcccctggcc ctcctttctg   1680

gctcagcctg cagcgactgt gaggccacag ctcctcagat tcactgcccg ctgtgtgcca   1740

gtactcaggc agctggagag aagagaaggc agcagcagag gcccccgccc tcaccccagc   1800

catctgcact tgtaccattt gctctgtgct gactgtggtc ctataaattc atgagaaata   1860

aactggttct gtgtgcctct ctga                                          1884


<210>  8475
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  8475

Met Glu Arg Pro Glu Pro Glu Leu Ile Arg Gln Ser Trp Arg Ala Val 
1               5                   10                  15


Ser Arg Ser Pro Leu Glu His Gly Thr Val Leu Phe Ala Arg Leu Phe 
            20                  25                  30


Ala Leu Glu Pro Asp Leu Leu Pro Leu Phe Gln Tyr Asn Cys Arg Gln 
        35                  40                  45


Phe Ser Ser Pro Glu Asp Cys Leu Ser Ser Pro Glu Phe Leu Asp His 
    50                  55                  60


Ile Arg Lys Val Met Leu Val Ile Asp Ala Ala Val Thr Asn Val Glu 
65                  70                  75                  80


Asp Leu Ser Ser Leu Glu Glu Tyr Leu Ala Ser Leu Gly Arg Lys His 
                85                  90                  95


Arg Ala Val Gly Val Lys Leu Ser Ser Phe Ser Thr Val Gly Glu Ser 
            100                 105                 110


Leu Leu Tyr Met Leu Glu Lys Cys Leu Gly Pro Ala Phe Thr Pro Ala 
        115                 120                 125


Thr Arg Ala Ala Trp Ser Gln Leu Tyr Gly Ala Val Val Gln Ala Met 
    130                 135                 140


Ser Arg Gly Trp Asp Gly Glu 
145                 150


<210>  8476
<211>  1057
<212>  DNA
<213>  Homo sapiens

<400>  8476
ccagttttat agaggagaaa acagaagccc ggggaggcta gaactcgcct aaggtcacac     60

agcttggatg tagtgcagcc acagcgggtg cctgagaaaa aacagtttgt gggacacatc    120

acgtttctgc caagtgctac agctgaagcc catattcata gaagcaccct gacagccctt    180

ctccagcaac ttccagaaaa cagaacctga gcactcaaag ctgcatcagc ccatgtggcc    240

ttgctcccag agaagcatct gccagtttgg gcatggagga acagaaagtg ggcagggaat    300

tctccttggc tccttagaag gcagtgggag cccagggaag cgttcggccc cagtgcagcc    360

taattgggag ggagggatgg gtagaggctg gctgggcttc tccttcctca ccctcatgca    420

aggtggctgc ccctctggct ccttcagagc tcttcccttc caagttccta ctgagaaata    480

agaaggcaca aaggaaaatc agccacctcc tggaggtcac tgtgggccac ctgctttgct    540

aagagccaag cacagacccc tgcattctcc ctgcaggaga gcccacccgg ctcagaagaa    600

agcaattccg cctgtgggga ggagaggaag ggaggggagg ggaggacaca cggtgaggtg    660

gaagcagcga gcagagcttc tccatccctc ctctccttcc ctgccagaaa tgcaattaag    720

caagtggccc agactcagcc gcacagacag cgcttcctgc tgggggaagt caaaagggct    780

gtagcagtgg gaaagggagg tcatcgggcc ccagatctaa ttaaccaacc tgccttgctt    840

ttgacgttgc tgcatttcct ctattaacat taatgatggt tggtctgaat gcccaagcat    900

ggccagaagc ttccctcccc accacccagt aggtagcaca gcctgtccct gggaccaata    960

tccagtctcc gtggcaaccg cctcctgaag atgctttaaa gagatctgac cctgtcagag   1020

ttgttgggag cttcagagga gggaaaatgg agtgtgg                            1057


<210>  8477
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  8477

Met Trp Pro Cys Ser Gln Arg Ser Ile Cys Gln Phe Gly His Gly Gly 
1               5                   10                  15


Thr Glu Ser Gly Gln Gly Ile Leu Leu Gly Ser Leu Glu Gly Ser Gly 
            20                  25                  30


Ser Pro Gly Lys Arg Ser Ala Pro Val Gln Pro Asn Trp Glu Gly Gly 
        35                  40                  45


Met Gly Arg Gly Trp Leu Gly Phe Ser Phe Leu Thr Leu Met Gln Gly 
    50                  55                  60


Gly Cys Pro Ser Gly Ser Phe Arg Ala Leu Pro Phe Gln Val Pro Thr 
65                  70                  75                  80


Glu Lys 



<210>  8478
<211>  4766
<212>  DNA
<213>  Homo sapiens

<400>  8478
ttatcatcct tcaagtgggg ctgaacacca ttgcagacct ttggtacctg ttcggagacc     60

tcagtctttc attggtgagc acccaagggt ttgctgtgga aatgtttttg ctccctgatg    120

ttgctgagta ggagctggtg gccttctctg tctctactgc aggtggcaga gtggctgtgt    180

tctgggtccc aggtgggctg gaccccccaa cctccgcaga cagcaggaca tcagggagtg    240

ggcccggctg aggactggat agggttcaag ggagaggata gattaacatt cttggaagtc    300

tctttttgca tttgttttat aatgtctgtg aactcacaat tttcatttcc tgacccacgg    360

tctccatatt tggaggccag taagggcctt tacagttggc catcactctg ctgtggtgct    420

gctccatcac ctccaaacca gctcctaaca agtttattca ttcattcatt catttattca    480

gaaaatgtgt aaagatcatc cgcgaagtta agataaggag ccattagcca tgtgatgggt    540

tgggctggga cagtagagga agcactggga aagttcaagg aggttagtgt acctggaaca    600

tggagcggac tggtgagcaa ctgtgttgca gatgcaggtg ccttgtcctt ggcacagtaa    660

catcctgggg ttttgggtgt agagcctgga gaggtagcag agggctggcc catgtttatc    720

ttgtgtagtg cttgggtggt gggtgttaca gaaaggctta gggtttccac atattcttct    780

ctctcctctt ggccattttt tatgattatg actgatatat taaaagctat atataatgca    840

tgcatagtgc ctaaggaata atgaggtctc acatgcctag caccccacgc tggcctctgt    900

ttgcaggtga ctgtgggaaa acacctgact gctcgtgtcc tgtgcctcat agtgctgccc    960

ctggctctct atacagccac ctttgctgtt cacttcatgg tgctgagtaa aagtggccct   1020

ggtgacggtt tcttcagttc tgccttccag gcccggcttt cagggaacaa cctgcacaat   1080

gcttccatcc ctgaacacct ggcctacggc tctgtgatca ctgtgaagaa cctccggatg   1140

gccatcggct atctgcactc ccacaggcac ctctaccccg agggcattgg tgcccgtcag   1200

cagcaggtca ccacctattt gcacaaggac tacaacaacc tgtggattat caagaaacat   1260

aacacaaact cagatcccct agacccttcc ttcccagtgg agtttgtaag acatggagac   1320

attattcgac tagaacacaa agaaacttcc cggaacttgc acagtcacta tcatgaggcc   1380

cccatgaccc ggaagcacta tcaggtcacc ggctatggca taaatggaac aggggactca   1440

aatgatttct ggcggattga ggtcgtaaac aggaaatttg gaaaccggat caaagtgctg   1500

agaagtcgaa ttcgcttcat ccatttggtc acaggttgtg tcctgggctc ctcgggaaag   1560

gttctgccca agtggggctg ggagcagttg gaagttactt gcaccccata cctgaaagaa   1620

accctcaact ccatctggaa tgtggaggac catatcaatc ccaagttgcc aaacatcagc   1680

ctggatgtgc tacagcccag ttttcctgag atcttgctgg aatcccacat ggtcatgatc   1740

cgggggaaca gtggcctcaa acccaaggac aatgagttca cgtccaaacc ctggcactgg   1800

cctatcaact atcagggcct acgcttctca ggggtcaatg acacagattt ccgagtctat   1860

ctgcttggca acccggtggt ttggtggctg aatctgttga gcatcgccct ctacctcctc   1920

tcagggagca tcattgctgt agccatgcag agaggggcac ggctgccagc ggaggttgca   1980

gggttgtccc aggtcctgct tcgaggaggc ggccaggtcc tgctcggctg gacactccat   2040

tacttcccgt ttttcctgat gggccgggtc ctctacttcc accactactt cccagccatg   2100

ctcttctcaa gcatgttgac aggcattctg tgggacaccc tcctgcggct ctgtgcctgg   2160

ggcttggcct catggcccct ggcgaggggc atacatgtgg cgggaatcct gagcctgctc   2220

ctgggaactg cctacagctt ctacctcttc caccctctgg cttacgggat ggttggtccc   2280

ctggcccagg acccccaaag tccaatggca ggactaaggt ggctggactc atgggacttt   2340

tgaggccact gcaaagattc cagcctgggt ccaggaactt cccaggagag ccagctggga   2400

agcagtactg gaccatccgg ccatgaggaa gctgcctaag gagcccgaag aattctgctg   2460

ctcaccagga cccagctctg ggagtgcagc tggaatggaa cccagcattg gagagagccg   2520

ggagagagcc gcagctccgt ccacagcacc acggagagga cagcgcctct tgggctgctc   2580

cctcgtgcac agcgcagggg aggatgggtg ccagagggtg ggagtgggtg cgcgtgtgtg   2640

tatgtgaggg catgttgtcc atatccctgt ggaatacaga ccgtgtaact ggacagctga   2700

gtgtcataaa ctctaaaata gtccaggcta tagtaatatt ttctggtatt tttttctgtt   2760

ggatttcttt ggttttggtt tgtaagatcc atcaaaaatt ctcagacctc tgagagggcc   2820

ttgagggcag agaatactga cctcaccttg ggatgtcacc aaaggcagag cagatgggac   2880

tgtcaaagtt gtgctgccct ccctcccaca aacaaatgaa tccagcgtgg aggaaggcgc   2940

gccgccccga gctggagggc ctggctccca ccatgccccc cagtggctgc aggtagctgg   3000

acttcctgcc tgtgacgcac agagagcagc ggactccgga gcgtcagcct gccttagccc   3060

ttggttcctc gttttttggg attgtcacac tgtgacactc gggaggaacg atgtcctatc   3120

ctgggctgct cagtgttccc aggccctgtg tgccagaggc caggtctctc caagtgcatc   3180

tagcctggcc tggagggcaa ggcagatgca ttctcctggc tgctgggaga gcccatggga   3240

accttgctta gcgcccaagg tagatgagag acagggcagg gaatctgcgt ggtgctggga   3300

tgtggggact ctggcctctc cagactaatg ttcctgtcac ctgctgagct ttcccagtgt   3360

cacttctgca gtcctcctct gctcacccct ccctcactcc gtgggcaatt ccctttctct   3420

ctgtcactgc ttcagcagtg aagacccatg gcacctagaa atgcatgcca gcttcctgcg   3480

tctaccactc tgcagctcaa acaagaagct cagagctgcc ccttccactt cctccccaaa   3540

agggatgaag aaaaccctgt ggtagaacca aaccacccaa ggccagccct taagcctgcc   3600

tccaccttcc tggtgcatga caaaatattt cttttgtctc agaggacttt gatgcttcaa   3660

tatttaatga tgaatccgcc acactccatt ttccctcctc tgaagctccc aacaactctg   3720

acagggtcag atctctttaa agcatcttca ggaggcggtt gccacggaga ctggatattg   3780

gtcccaggga caggctgtgc tacctactgg gtggtgggga gggaagcttc tggccatgct   3840

tgggcattca gaccaaccat cattaatgtt aatagaggaa atgcagcaac gtcaaaagca   3900

aggcaggttg gttaattaga tctggggccc gatgacctcc ctttcccact gctacagccc   3960

ttttgacttc ccccagcagg aagcgctgtc tgtgcggctg agtctgggcc acttgcttaa   4020

ttgcatttct ggcagggaag gagaggaggg atggagaagc tctgctcgct gcttccacct   4080

caccgtgtgt cctcccctcc cctcccttcc tctcctcccc acaggcggaa ttgctttctt   4140

ctgagccggg tgggctctcc tgcagggaga atgcaggggt ctgtgcttgg ctcttagcaa   4200

agcaggtggc ccacagtgac ctccaggagg tggctgattt tcctttgtgc cttcttattt   4260

ctcagtagga acttggaagg gaagagctct gaaggagcca gaggggcagc caccttgcat   4320

gagggtgagg aaggagaagc ccagccagcc tctacccatc cctccctccc aattaggctg   4380

cactggggcc gaacgcttcc ctgggctccc actgccttct aaggagccaa ggagaattcc   4440

ctgcccactt tctgttcctc catgcccaaa ctggcagatg cttctctggg agcaaggcca   4500

catgggctga tgcagctttg agtgctcagg ttctgttttc tggaagttgc tggagaaggg   4560

ctgtcagggt gcttctatga atatgggctt cagctgtagc acttggcaga aacgtgatgt   4620

gtcccacaaa ctgctggtgg aggaagaaga tgttcgtcag ccaattcaac ctccagccag   4680

cttcttgagc ctatttggtt taaaaaaaaa aagtcttcta atcagaagcc actgatttta   4740

taataaataa cacttgtttt gaatgc                                        4766


<210>  8479
<211>  448
<212>  PRT
<213>  Homo sapiens

<400>  8479

Met Val Leu Ser Lys Ser Gly Pro Gly Asp Gly Phe Phe Ser Ser Ala 
1               5                   10                  15


Phe Gln Ala Arg Leu Ser Gly Asn Asn Leu His Asn Ala Ser Ile Pro 
            20                  25                  30


Glu His Leu Ala Tyr Gly Ser Val Ile Thr Val Lys Asn Leu Arg Met 
        35                  40                  45


Ala Ile Gly Tyr Leu His Ser His Arg His Leu Tyr Pro Glu Gly Ile 
    50                  55                  60


Gly Ala Arg Gln Gln Gln Val Thr Thr Tyr Leu His Lys Asp Tyr Asn 
65                  70                  75                  80


Asn Leu Trp Ile Ile Lys Lys His Asn Thr Asn Ser Asp Pro Leu Asp 
                85                  90                  95


Pro Ser Phe Pro Val Glu Phe Val Arg His Gly Asp Ile Ile Arg Leu 
            100                 105                 110


Glu His Lys Glu Thr Ser Arg Asn Leu His Ser His Tyr His Glu Ala 
        115                 120                 125


Pro Met Thr Arg Lys His Tyr Gln Val Thr Gly Tyr Gly Ile Asn Gly 
    130                 135                 140


Thr Gly Asp Ser Asn Asp Phe Trp Arg Ile Glu Val Val Asn Arg Lys 
145                 150                 155                 160


Phe Gly Asn Arg Ile Lys Val Leu Arg Ser Arg Ile Arg Phe Ile His 
                165                 170                 175


Leu Val Thr Gly Cys Val Leu Gly Ser Ser Gly Lys Val Leu Pro Lys 
            180                 185                 190


Trp Gly Trp Glu Gln Leu Glu Val Thr Cys Thr Pro Tyr Leu Lys Glu 
        195                 200                 205


Thr Leu Asn Ser Ile Trp Asn Val Glu Asp His Ile Asn Pro Lys Leu 
    210                 215                 220


Pro Asn Ile Ser Leu Asp Val Leu Gln Pro Ser Phe Pro Glu Ile Leu 
225                 230                 235                 240


Leu Glu Ser His Met Val Met Ile Arg Gly Asn Ser Gly Leu Lys Pro 
                245                 250                 255


Lys Asp Asn Glu Phe Thr Ser Lys Pro Trp His Trp Pro Ile Asn Tyr 
            260                 265                 270


Gln Gly Leu Arg Phe Ser Gly Val Asn Asp Thr Asp Phe Arg Val Tyr 
        275                 280                 285


Leu Leu Gly Asn Pro Val Val Trp Trp Leu Asn Leu Leu Ser Ile Ala 
    290                 295                 300


Leu Tyr Leu Leu Ser Gly Ser Ile Ile Ala Val Ala Met Gln Arg Gly 
305                 310                 315                 320


Ala Arg Leu Pro Ala Glu Val Ala Gly Leu Ser Gln Val Leu Leu Arg 
                325                 330                 335


Gly Gly Gly Gln Val Leu Leu Gly Trp Thr Leu His Tyr Phe Pro Phe 
            340                 345                 350


Phe Leu Met Gly Arg Val Leu Tyr Phe His His Tyr Phe Pro Ala Met 
        355                 360                 365


Leu Phe Ser Ser Met Leu Thr Gly Ile Leu Trp Asp Thr Leu Leu Arg 
    370                 375                 380


Leu Cys Ala Trp Gly Leu Ala Ser Trp Pro Leu Ala Arg Gly Ile His 
385                 390                 395                 400


Val Ala Gly Ile Leu Ser Leu Leu Leu Gly Thr Ala Tyr Ser Phe Tyr 
                405                 410                 415


Leu Phe His Pro Leu Ala Tyr Gly Met Val Gly Pro Leu Ala Gln Asp 
            420                 425                 430


Pro Gln Ser Pro Met Ala Gly Leu Arg Trp Leu Asp Ser Trp Asp Phe 
        435                 440                 445


<210>  8480
<211>  5807
<212>  DNA
<213>  Homo sapiens

<400>  8480
cccgggccgc gaccacgctg cccgccccgc cccgagcccg gggccccgcg ctccgctgca     60

gtgaagggcg ttgcatttcc cggggtaccc cgagctgccc tcttgtgact ccttggcggg    120

gcggctggtc agacaaagtg tgcctccggg ccggagggcg acccagagga gggggaagat    180

gccgccggcc acgggcggag gcctggcaga gtccgagctg cgtccccgga ggggccgctg    240

tggcccccag gctgctaggg ccgcaggccg ggacgtggcc gctgaggctg tggcgcgaag    300

ccccaaacgg cctgcttggg gctcacggcg cttcgaggcg gtcggctggt gggccctgct    360

ggccttggtg acgctgctgt ccttcgccac ccgcttccac cgcttggacg agccgccgca    420

catctgttgg gatgagactc actttggaaa aatgggaagt tactatatca accgtacatt    480

tttctttgat gtgcacccgc ccctgggaaa gatgctgata ggtcttgctg gctacctgag    540

tggatatgat ggtacctttt tgttccagaa gcctggggat aaatatgagc atcacagcta    600

catgggaatg agaggattct gtgcattcct tggctcctgg ctggtcccct ttgcctacct    660

cactgtactg gatctgtcca agtccctctc ggcagcactg ctcacagctg ccctcctcac    720

ctttgacacg ggatgcctca ctctgtccca gtacatcctc cttgacccca tcctgatgtt    780

cttcatcatg gctgccatgc tgagcatggt caagtacaac tcttgcgccg acaggccctt    840

ctctgccccc tggtggttct ggctcagcct gactggcgtt agtcttgctg gtgctttagg    900

ggtcaagttt gttggcctct ttatcatcct tcaagtgggg ctgaacacca ttgcagacct    960

ttggtacctg ttcggagacc tcagtctttc attggtgact gtgggaaaac acctgactgc   1020

tcgtgtcctg tgcctcatag tgctgcccct ggctctctat acagccacct ttgctgttca   1080

cttcatggtg ctgagtaaaa gtggccctgg tgacggtttc ttcagttctg ccttccaggc   1140

ccggctttca gggaacaacc tgcacaatgc ttccatccct gaacacctgg cctacggctc   1200

tgtgatcact gtgaagaacc tccggatggc catcggctat ctgcactccc acaggcacct   1260

ctaccccgag ggcattggtg cccgtcagca gcaggtcacc acctatttgc acaaggacta   1320

caacaacctg tggattatca agaaacataa cacaaactca gatcccctag acccttcctt   1380

cccagtggag tttgtaagac atggagacat tattcgacta gaacacaaag aaacttcccg   1440

gaacttgcac agtcactatc atgaggcccc catgacccgg aagcactatc aggtcaccgg   1500

ctatggcata aatggaacag gggactcaaa tgatttctgg cggattgagg tcgtaaacag   1560

gaaatttgga aaccggatca aagtgctgag aagtcgaatt cgcttcatcc atttggtcac   1620

aggttgtgtc ctgggctcct cgggaaaggt tctgcccaag tggggctggg agcagttgga   1680

agttacttgc accccatacc tgaaagaaac cctcaactcc atctggaatg tggaggacca   1740

tatcaatccc aagttgccaa acatcagcct ggatgtgcta cagcccagtt ttcctgagat   1800

cttgctggaa tcccacatgg tcatgatccg ggggaacagt ggcctcaaac ccaaggacaa   1860

tgagttcacg tccaaaccct ggcactggcc tatcaactat cagggcctac gcttctcagg   1920

ggtcaatgac acagatttcc gagtctatct gcttggcaac ccggtggttt ggtggctgaa   1980

tctgttgagc atcgccctct acctcctctc agggagcatc attgctgtag ccatgcagag   2040

aggggcacgg ctgccagcgg aggttgcagg tcaggtcctc tgggctctcc ctcccctgac   2100

ctggcggcag cagggcacct gcacccctgg ggagggccgg ctgcctgctg atgggccatc   2160

ctttgcgttt accaccccac accttccctt atcctttgct tttgaaaggt aacaaccccc   2220

aagtacccag tgctgtgtta aacactttac ttcctcccaa caacactaga gcgttggcta   2280

ttatgacccc cattttatgg attaggaaac caaggaacca tgagattaag aaacttgccc   2340

caggacatac agctagtaag tgatagagct gaggctcaaa cccgtgcaat ctgactccac   2400

agccctcact tttagcccca tgctgtgtac agagctgccc atcttttctg ccacctcctt   2460

gttccatggc cctgtcctct catgggctag agaggagcct ccagggttat tgagttccca   2520

tcccagtgct gttcttggta actttggctg ccagaccatg ggccacagca cctgagacag   2580

tcacacaggc ccttttgcct ctgcagctct ctgtctgaac agtcatagtc ccagacacct   2640

cctcactcca tcctcacctg taacctcacc ttagcgcctg tctgccgctg caaagatctg   2700

tgtggcagca aagatgtggg aggtggaagt agggagtgaa gctgtctgca ggcgcagaag   2760

ggtttcttta gaggctgggc tgcctcctgc tggtgcttgg tgcacctgcc attggtgccc   2820

aggcctcact aggctgggcc ctgaccagag ctctcgagcc ccagctgctc ctctccagtt   2880

tctgtagcgt ggtttgggtt ggtccaatga ggtgatatga catattcaag gtcacacagc   2940

aaggaagggg cagagctgga ccagagcctg gaatctctgc ccgctccttg tcttctgact   3000

gggctgtgct gcttgggccc agggttgtcc caggtcctgc ttcgaggagg cggccaggtc   3060

ctgctcggct ggacactcca ttacttcccg tttttcctga tgggccgggt cctctacttc   3120

caccactact tcccagccat gctcttctca agcatgttga caggcattct gtgggacacc   3180

ctcctgcggc tctgtgcctg gggcttggcc tcatggcccc tggcgagggg catacatgtg   3240

gcgggaatcc tgagcctgct cctgggaact gcctacagct tctacctctt ccaccctctg   3300

gcttacggga tggttggtcc cctggcccag gacccccaaa gtccaatggc aggactaagg   3360

tggctggact catgggactt ttgaggccac tgcaaagatt ccagcctggg tccaggaact   3420

tcccaggaga gccagctggg aagcagtact ggaccatccg gccatgagga agctgcctaa   3480

ggagcccgaa gaattctgct gctcaccagg acccagctct gggagtgcag ctggaatgga   3540

acccagcatt ggagagagcc gggagagagc cgcagctccg tccacagcac cacggagagg   3600

acagcgcctc ttgggctgct ccctcgtgca cagcgcaggg gaggatgggt gccagagggt   3660

gggagtgggt gcgcgtgtgt gtatgtgagg gcatgttgtc catatccctg tggaatacag   3720

accgtgtaac tggacagctg agtgtcataa actctaaaat agtccaggct atagtaatat   3780

tttctggtat ttttttctgt tggatttctt tggttttggt ttgtaagatc catcaaaaat   3840

tctcagacct ctgagagggc cttgagggca gagaatactg acctcacctt gggatgtcac   3900

caaaggcaga gcagatggga ctgtcaaagt tgtgctgccc tccctcccac aaacaaatga   3960

atccagcgtg gaggaaggcg cgccgccccg agctggaggg cctggctccc accatgcccc   4020

ccagtggctg caggtagctg gacttcctgc ctgtgacgca cagagagcag cggactccgg   4080

agcgtcagcc tgccttagcc cttggttcct cgttttttgg gattgtcaca ctgtgacact   4140

cgggaggaac gatgtcctat cctgggctgc tcagtgttcc caggccctgt gtgccagagg   4200

ccaggtctct ccaagtgcat ctagcctggc ctggagggca aggcagatgc attctcctgg   4260

ctgctgggag agcccatggg aaccttgctt agcgcccaag gtagatgaga gacagggcag   4320

ggaatctgcg tggtgctggg atgtggggac tctggcctct ccagactaat gttcctgtca   4380

cctgctgagc tttcccagtg tcacttctgc agtcctcctc tgctcacccc tccctcactc   4440

cgtgggcaat tccctttctc tctgtcactg cttcagcagt gaagacccat ggcacctaga   4500

aatgcatgcc agcttcctgc gtctaccact ctgcagctca aacaagaagc tcagagctgc   4560

cccttccact tcctccccaa aagggatgaa gaaaaccctg tggtagaacc aaaccaccca   4620

aggccagccc ttaagcctgc ctccaccttc ctggtgcatg acaaaatatt tcttttgtct   4680

cagaggactt tgatgcttca atatttaatg atgaatccgc cacactccat tttccctcct   4740

ctgaagctcc caacaactct gacagggtca gatctcttta aagcatcttc aggaggcggt   4800

tgccacggag actggatatt ggtcccaggg acaggctgtg ctacctactg ggtggtgggg   4860

agggaagctt ctggccatgc ttgggcattc agaccaacca tcattaatgt taatagagga   4920

aatgcagcaa cgtcaaaagc aaggcaggtt ggttaattag atctggggcc cgatgacctc   4980

cctttcccac tgctacagcc cttttgactt cccccagcag gaagcgctgt ctgtgcggct   5040

gagtctgggc cacttgctta attgcatttc tggcagggaa ggagaggagg gatggagaag   5100

ctctgctcgc tgcttccacc tcaccgtgtg tcctcccctc ccctcccttc ctctcctccc   5160

cacaggcgga attgctttct tctgagccgg gtgggctctc ctgcagggag aatgcagggg   5220

tctgtgcttg gctcttagca aagcaggtgg cccacagtga cctccaggag gtggctgatt   5280

ttcctttgtg ccttcttatt tctcagtagg aacttggaag ggaagagctc tgaaggagcc   5340

agaggggcag ccaccttgca tgagggtgag gaaggagaag cccagccagc ctctacccat   5400

ccctccctcc caattaggct gcactggggc cgaacgcttc cctgggctcc cactgccttc   5460

taaggagcca aggagaattc cctgcccact ttctgttcct ccatgcccaa actggcagat   5520

gcttctctgg gagcaaggcc acatgggctg atgcagcttt gagtgctcag gttctgtttt   5580

ctggaagttg ctggagaagg gctgtcaggg tgcttctatg aatatgggct tcagctgtag   5640

cacttggcag aaacgtgatg tgtcccacaa actgctggtg gaggaagaag atgttcgtca   5700

gccaattcaa cctccagcca gcttcttgag cctatttggt ttaaaaaaaa aaagtcttct   5760

aatcagaagc cactgatttt ataataaata acacttgttt tgaatgc                 5807


<210>  8481
<211>  677
<212>  PRT
<213>  Homo sapiens

<400>  8481

Met Pro Pro Ala Thr Gly Gly Gly Leu Ala Glu Ser Glu Leu Arg Pro 
1               5                   10                  15


Arg Arg Gly Arg Cys Gly Pro Gln Ala Ala Arg Ala Ala Gly Arg Asp 
            20                  25                  30


Val Ala Ala Glu Ala Val Ala Arg Ser Pro Lys Arg Pro Ala Trp Gly 
        35                  40                  45


Ser Arg Arg Phe Glu Ala Val Gly Trp Trp Ala Leu Leu Ala Leu Val 
    50                  55                  60


Thr Leu Leu Ser Phe Ala Thr Arg Phe His Arg Leu Asp Glu Pro Pro 
65                  70                  75                  80


His Ile Cys Trp Asp Glu Thr His Phe Gly Lys Met Gly Ser Tyr Tyr 
                85                  90                  95


Ile Asn Arg Thr Phe Phe Phe Asp Val His Pro Pro Leu Gly Lys Met 
            100                 105                 110


Leu Ile Gly Leu Ala Gly Tyr Leu Ser Gly Tyr Asp Gly Thr Phe Leu 
        115                 120                 125


Phe Gln Lys Pro Gly Asp Lys Tyr Glu His His Ser Tyr Met Gly Met 
    130                 135                 140


Arg Gly Phe Cys Ala Phe Leu Gly Ser Trp Leu Val Pro Phe Ala Tyr 
145                 150                 155                 160


Leu Thr Val Leu Asp Leu Ser Lys Ser Leu Ser Ala Ala Leu Leu Thr 
                165                 170                 175


Ala Ala Leu Leu Thr Phe Asp Thr Gly Cys Leu Thr Leu Ser Gln Tyr 
            180                 185                 190


Ile Leu Leu Asp Pro Ile Leu Met Phe Phe Ile Met Ala Ala Met Leu 
        195                 200                 205


Ser Met Val Lys Tyr Asn Ser Cys Ala Asp Arg Pro Phe Ser Ala Pro 
    210                 215                 220


Trp Trp Phe Trp Leu Ser Leu Thr Gly Val Ser Leu Ala Gly Ala Leu 
225                 230                 235                 240


Gly Val Lys Phe Val Gly Leu Phe Ile Ile Leu Gln Val Gly Leu Asn 
                245                 250                 255


Thr Ile Ala Asp Leu Trp Tyr Leu Phe Gly Asp Leu Ser Leu Ser Leu 
            260                 265                 270


Val Thr Val Gly Lys His Leu Thr Ala Arg Val Leu Cys Leu Ile Val 
        275                 280                 285


Leu Pro Leu Ala Leu Tyr Thr Ala Thr Phe Ala Val His Phe Met Val 
    290                 295                 300


Leu Ser Lys Ser Gly Pro Gly Asp Gly Phe Phe Ser Ser Ala Phe Gln 
305                 310                 315                 320


Ala Arg Leu Ser Gly Asn Asn Leu His Asn Ala Ser Ile Pro Glu His 
                325                 330                 335


Leu Ala Tyr Gly Ser Val Ile Thr Val Lys Asn Leu Arg Met Ala Ile 
            340                 345                 350


Gly Tyr Leu His Ser His Arg His Leu Tyr Pro Glu Gly Ile Gly Ala 
        355                 360                 365


Arg Gln Gln Gln Val Thr Thr Tyr Leu His Lys Asp Tyr Asn Asn Leu 
    370                 375                 380


Trp Ile Ile Lys Lys His Asn Thr Asn Ser Asp Pro Leu Asp Pro Ser 
385                 390                 395                 400


Phe Pro Val Glu Phe Val Arg His Gly Asp Ile Ile Arg Leu Glu His 
                405                 410                 415


Lys Glu Thr Ser Arg Asn Leu His Ser His Tyr His Glu Ala Pro Met 
            420                 425                 430


Thr Arg Lys His Tyr Gln Val Thr Gly Tyr Gly Ile Asn Gly Thr Gly 
        435                 440                 445


Asp Ser Asn Asp Phe Trp Arg Ile Glu Val Val Asn Arg Lys Phe Gly 
    450                 455                 460


Asn Arg Ile Lys Val Leu Arg Ser Arg Ile Arg Phe Ile His Leu Val 
465                 470                 475                 480


Thr Gly Cys Val Leu Gly Ser Ser Gly Lys Val Leu Pro Lys Trp Gly 
                485                 490                 495


Trp Glu Gln Leu Glu Val Thr Cys Thr Pro Tyr Leu Lys Glu Thr Leu 
            500                 505                 510


Asn Ser Ile Trp Asn Val Glu Asp His Ile Asn Pro Lys Leu Pro Asn 
        515                 520                 525


Ile Ser Leu Asp Val Leu Gln Pro Ser Phe Pro Glu Ile Leu Leu Glu 
    530                 535                 540


Ser His Met Val Met Ile Arg Gly Asn Ser Gly Leu Lys Pro Lys Asp 
545                 550                 555                 560


Asn Glu Phe Thr Ser Lys Pro Trp His Trp Pro Ile Asn Tyr Gln Gly 
                565                 570                 575


Leu Arg Phe Ser Gly Val Asn Asp Thr Asp Phe Arg Val Tyr Leu Leu 
            580                 585                 590


Gly Asn Pro Val Val Trp Trp Leu Asn Leu Leu Ser Ile Ala Leu Tyr 
        595                 600                 605


Leu Leu Ser Gly Ser Ile Ile Ala Val Ala Met Gln Arg Gly Ala Arg 
    610                 615                 620


Leu Pro Ala Glu Val Ala Gly Gln Val Leu Trp Ala Leu Pro Pro Leu 
625                 630                 635                 640


Thr Trp Arg Gln Gln Gly Thr Cys Thr Pro Gly Glu Gly Arg Leu Pro 
                645                 650                 655


Ala Asp Gly Pro Ser Phe Ala Phe Thr Thr Pro His Leu Pro Leu Ser 
            660                 665                 670


Phe Ala Phe Glu Arg 
        675


<210>  8482
<211>  4869
<212>  DNA
<213>  Homo sapiens

<400>  8482
gccgcctcct agcggcccgg gccgcgacca cgctgcccgc cccgccccga gcccggggcc     60

ccgcgctccg ctgcagtgaa gggcgttgca tttcccgggg taccccgagc tgccctcttg    120

tgactccttg gcggggcggc tggtcagaca aagtgtgcct ccgggccgga gggcgaccca    180

gaggaggggg aagatgccgc cggccacggg cggaggcctg gcagagtccg agctgcgtcc    240

ccggaggggc cgctgtggcc cccaggctgc tagggccgca ggccgggacg tggccgctga    300

ggctgtggcg cgaagcccca aacggcctgc ttggggctca cggcgcttcg aggcggtcgg    360

ctggtgggcc ctgctggcct tggtgacgct gctgtccttc gccacccgct tccaccgctt    420

ggacgagccg ccgcacatct gttgggatga gactcacttt ggaaaaatgg gaagttacta    480

tatcaaccgt acatttttct ttgatgtgca cccgcccctg ggaaagatgc tgataggtct    540

tgctggctac ctgagtggat atgatggtac ctttttgttc cagaagcctg gggataaata    600

tgagcatcac agctacatgg gaatgagagg attctgtgca ttccttggct cctggctggt    660

cccctttgcc tacctcactg tactggatct gtccaagtcc ctctcggcag cactgctcac    720

agctgccctc ctcacctttg acacgggatg cctcactctg tcccagtaca tcctccttga    780

ccccatcctg atgttcttca tcatggctgc catgctgagc atggtcaagt acaactcttg    840

cgccgacagg cccttctctg ccccctggtg gttctggctc agcctgactg gcgttagtct    900

tgctggtgct ttaggggtca agtttgttgg cctctttatc atccttcaag tggggctgaa    960

caccattgca gacctttggt acctgttcgg agacctcagt ctttcattgg tgactgtggg   1020

aaaacacctg actgctcgtg tcctgtgcct catagtgctg cccctggctc tctatacagc   1080

cacctttgct gttcacttca tggtgctgag taaaagtggc cctggtgacg gtttcttcag   1140

ttctgccttc caggcccggc tttcagggaa caacctgcac aatgcttcca tccctgaaca   1200

cctggcctac ggctctgtga tcactgtgaa gaacctccgg atggccatcg gctatctgca   1260

ctcccacagg cacctctacc ccgagggcat tggtgcccgt cagcagcagg tcaccaccta   1320

tttgcacaag gactacaaca acctgtggat tatcaagaaa cataacacaa actcagatcc   1380

cctagaccct tccttcccag tggagtttgt aagacatgga gacattattc gactagaaca   1440

caaagaaact tcccggaact tgcacagtca ctatcatgag gcccccatga cccggaagca   1500

ctatcaggtc accggctatg gcataaatgg aacaggggac tcaaatgatt tctggcggat   1560

tgaggtcgta aacaggaaat ttggaaaccg gatcaaagtg ctgagaagtc gaattcgctt   1620

catccatttg gtcacaggtt gtgtcctggg ctcctcggga aaggttctgc ccaagtgggg   1680

ctgggagcag ttggaagtta cttgcacccc atacctgaaa gaaaccctca actccatctg   1740

gaatgtggag gaccatatca atcccaagtt gccaaacatc agcctggatg tgctacagcc   1800

cagttttcct gagatcttgc tggaatccca catggtcatg atccggggga acagtggcct   1860

caaacccaag gacaatgagt tcacgtccaa accctggcac tggcctatca actatcaggg   1920

cctacgcttc tcaggggtca atgacacaga tttccgagtc tatctgcttg gcaacccggt   1980

ggtttggtgg ctgaatctgt tgagcatcgc cctctacctc ctctcaggga gcatcattgc   2040

tgtagccatg cagagagggg cacggctgcc agcggaggtt gcagggttgt cccaggtcct   2100

gcttcgagga ggcggccagg tcctgctcgg ctggacactc cattacttcc cgtttttcct   2160

gatgggccgg gtcctctact tccaccacta cttcccagcc atgctcttct caagcatgtt   2220

gacaggcatt ctgtgggaca ccctcctgcg gctctgtgcc tggggcttgg cctcatggcc   2280

cctggcgagg ggcatacatg tggcgggaat cctgagcctg ctcctgggaa ctgcctacag   2340

cttctacctc ttccaccctc tggcttacgg gatggttggt cccctggccc aggaccccca   2400

aagtccaatg gcaggactaa ggtggctgga ctcatgggac ttttgaggcc actgcaaaga   2460

ttccagcctg ggtccaggaa cttcccagga gagccagctg ggaagcagta ctggaccatc   2520

cggccatgag gaagctgcct aaggagcccg aagaattctg ctgctcacca ggacccagct   2580

ctgggagtgc agctggaatg gaacccagca ttggagagag ccgggagaga gccgcagctc   2640

cgtccacagc accacggaga ggacagcgcc tcttgggctg ctccctcgtg cacagcgcag   2700

gggaggatgg gtgccagagg gtgggagtgg gtgcgcgtgt gtgtatgtga gggcatgttg   2760

tccatatccc tgtggaatac agaccgtgta actggacagc tgagtgtcat aaactctaaa   2820

atagtccagg ctatagtaat attttctggt atttttttct gttggatttc tttggttttg   2880

gtttgtaaga tccatcaaaa attctcagac ctctgagagg gccttgaggg cagagaatac   2940

tgacctcacc ttgggatgtc accaaaggca gagcagatgg gactgtcaaa gttgtgctgc   3000

cctccctccc acaaacaaat gaatccagcg tggaggaagg cgcgccgccc cgagctggag   3060

ggcctggctc ccaccatgcc ccccagtggc tgcaggtagc tggacttcct gcctgtgacg   3120

cacagagagc agcggactcc ggagcgtcag cctgccttag cccttggttc ctcgtttttt   3180

gggattgtca cactgtgaca ctcgggagga acgatgtcct atcctgggct gctcagtgtt   3240

cccaggccct gtgtgccaga ggccaggtct ctccaagtgc atctagcctg gcctggaggg   3300

caaggcagat gcattctcct ggctgctggg agagcccatg ggaaccttgc ttagcgccca   3360

aggtagatga gagacagggc agggaatctg cgtggtgctg ggatgtgggg actctggcct   3420

ctccagacta atgttcctgt cacctgctga gctttcccag tgtcacttct gcagtcctcc   3480

tctgctcacc cctccctcac tccgtgggca attccctttc tctctgtcac tgcttcagca   3540

gtgaagaccc atggcaccta gaaatgcatg ccagcttcct gcgtctacca ctctgcagct   3600

caaacaagaa gctcagagct gccccttcca cttcctcccc aaaagggatg aagaaaaccc   3660

tgtggtagaa ccaaaccacc caaggccagc ccttaagcct gcctccacct tcctggtgca   3720

tgacaaaata tttcttttgt ctcagaggac tttgatgctt caatatttaa tgatgaatcc   3780

gccacactcc attttccctc ctctgaagct cccaacaact ctgacagggt cagatctctt   3840

taaagcatct tcaggaggcg gttgccacgg agactggata ttggtcccag ggacaggctg   3900

tgctacctac tgggtggtgg ggagggaagc ttctggccat gcttgggcat tcagaccaac   3960

catcattaat gttaatagag gaaatgcagc aacgtcaaaa gcaaggcagg ttggttaatt   4020

agatctgggg cccgatgacc tccctttccc actgctacag cccttttgac ttcccccagc   4080

aggaagcgct gtctgtgcgg ctgagtctgg gccacttgct taattgcatt tctggcaggg   4140

aaggagagga gggatggaga agctctgctc gctgcttcca cctcaccgtg tgtcctcccc   4200

tcccctccct tcctctcctc cccacaggcg gaattgcttt cttctgagcc gggtgggctc   4260

tcctgcaggg agaatgcagg ggtctgtgct tggctcttag caaagcaggt ggcccacagt   4320

gacctccagg aggtggctga ttttcctttg tgccttctta tttctcagta ggaacttgga   4380

agggaagagc tctgaaggag ccagaggggc agccaccttg catgagggtg aggaaggaga   4440

agcccagcca gcctctaccc atccctccct cccaattagg ctgcactggg gccgaacgct   4500

tccctgggct cccactgcct tctaaggagc caaggagaat tccctgccca ctttctgttc   4560

ctccatgccc aaactggcag atgcttctct gggagcaagg ccacatgggc tgatgcagct   4620

ttgagtgctc aggttctgtt ttctggaagt tgctggagaa gggctgtcag ggtgcttcta   4680

tgaatatggg cttcagctgt agcacttggc agaaacgtga tgtgtcccac aaactgctgg   4740

tggaggaaga agatgttcgt cagccaattc aacctccagc cagcttcttg agcctatttg   4800

gtttaaaaaa aaaaagtctt ctaatcagaa gccactgatt ttataataaa taacacttgt   4860

tttgaatgc                                                           4869


<210>  8483
<211>  750
<212>  PRT
<213>  Homo sapiens

<400>  8483

Met Pro Pro Ala Thr Gly Gly Gly Leu Ala Glu Ser Glu Leu Arg Pro 
1               5                   10                  15


Arg Arg Gly Arg Cys Gly Pro Gln Ala Ala Arg Ala Ala Gly Arg Asp 
            20                  25                  30


Val Ala Ala Glu Ala Val Ala Arg Ser Pro Lys Arg Pro Ala Trp Gly 
        35                  40                  45


Ser Arg Arg Phe Glu Ala Val Gly Trp Trp Ala Leu Leu Ala Leu Val 
    50                  55                  60


Thr Leu Leu Ser Phe Ala Thr Arg Phe His Arg Leu Asp Glu Pro Pro 
65                  70                  75                  80


His Ile Cys Trp Asp Glu Thr His Phe Gly Lys Met Gly Ser Tyr Tyr 
                85                  90                  95


Ile Asn Arg Thr Phe Phe Phe Asp Val His Pro Pro Leu Gly Lys Met 
            100                 105                 110


Leu Ile Gly Leu Ala Gly Tyr Leu Ser Gly Tyr Asp Gly Thr Phe Leu 
        115                 120                 125


Phe Gln Lys Pro Gly Asp Lys Tyr Glu His His Ser Tyr Met Gly Met 
    130                 135                 140


Arg Gly Phe Cys Ala Phe Leu Gly Ser Trp Leu Val Pro Phe Ala Tyr 
145                 150                 155                 160


Leu Thr Val Leu Asp Leu Ser Lys Ser Leu Ser Ala Ala Leu Leu Thr 
                165                 170                 175


Ala Ala Leu Leu Thr Phe Asp Thr Gly Cys Leu Thr Leu Ser Gln Tyr 
            180                 185                 190


Ile Leu Leu Asp Pro Ile Leu Met Phe Phe Ile Met Ala Ala Met Leu 
        195                 200                 205


Ser Met Val Lys Tyr Asn Ser Cys Ala Asp Arg Pro Phe Ser Ala Pro 
    210                 215                 220


Trp Trp Phe Trp Leu Ser Leu Thr Gly Val Ser Leu Ala Gly Ala Leu 
225                 230                 235                 240


Gly Val Lys Phe Val Gly Leu Phe Ile Ile Leu Gln Val Gly Leu Asn 
                245                 250                 255


Thr Ile Ala Asp Leu Trp Tyr Leu Phe Gly Asp Leu Ser Leu Ser Leu 
            260                 265                 270


Val Thr Val Gly Lys His Leu Thr Ala Arg Val Leu Cys Leu Ile Val 
        275                 280                 285


Leu Pro Leu Ala Leu Tyr Thr Ala Thr Phe Ala Val His Phe Met Val 
    290                 295                 300


Leu Ser Lys Ser Gly Pro Gly Asp Gly Phe Phe Ser Ser Ala Phe Gln 
305                 310                 315                 320


Ala Arg Leu Ser Gly Asn Asn Leu His Asn Ala Ser Ile Pro Glu His 
                325                 330                 335


Leu Ala Tyr Gly Ser Val Ile Thr Val Lys Asn Leu Arg Met Ala Ile 
            340                 345                 350


Gly Tyr Leu His Ser His Arg His Leu Tyr Pro Glu Gly Ile Gly Ala 
        355                 360                 365


Arg Gln Gln Gln Val Thr Thr Tyr Leu His Lys Asp Tyr Asn Asn Leu 
    370                 375                 380


Trp Ile Ile Lys Lys His Asn Thr Asn Ser Asp Pro Leu Asp Pro Ser 
385                 390                 395                 400


Phe Pro Val Glu Phe Val Arg His Gly Asp Ile Ile Arg Leu Glu His 
                405                 410                 415


Lys Glu Thr Ser Arg Asn Leu His Ser His Tyr His Glu Ala Pro Met 
            420                 425                 430


Thr Arg Lys His Tyr Gln Val Thr Gly Tyr Gly Ile Asn Gly Thr Gly 
        435                 440                 445


Asp Ser Asn Asp Phe Trp Arg Ile Glu Val Val Asn Arg Lys Phe Gly 
    450                 455                 460


Asn Arg Ile Lys Val Leu Arg Ser Arg Ile Arg Phe Ile His Leu Val 
465                 470                 475                 480


Thr Gly Cys Val Leu Gly Ser Ser Gly Lys Val Leu Pro Lys Trp Gly 
                485                 490                 495


Trp Glu Gln Leu Glu Val Thr Cys Thr Pro Tyr Leu Lys Glu Thr Leu 
            500                 505                 510


Asn Ser Ile Trp Asn Val Glu Asp His Ile Asn Pro Lys Leu Pro Asn 
        515                 520                 525


Ile Ser Leu Asp Val Leu Gln Pro Ser Phe Pro Glu Ile Leu Leu Glu 
    530                 535                 540


Ser His Met Val Met Ile Arg Gly Asn Ser Gly Leu Lys Pro Lys Asp 
545                 550                 555                 560


Asn Glu Phe Thr Ser Lys Pro Trp His Trp Pro Ile Asn Tyr Gln Gly 
                565                 570                 575


Leu Arg Phe Ser Gly Val Asn Asp Thr Asp Phe Arg Val Tyr Leu Leu 
            580                 585                 590


Gly Asn Pro Val Val Trp Trp Leu Asn Leu Leu Ser Ile Ala Leu Tyr 
        595                 600                 605


Leu Leu Ser Gly Ser Ile Ile Ala Val Ala Met Gln Arg Gly Ala Arg 
    610                 615                 620


Leu Pro Ala Glu Val Ala Gly Leu Ser Gln Val Leu Leu Arg Gly Gly 
625                 630                 635                 640


Gly Gln Val Leu Leu Gly Trp Thr Leu His Tyr Phe Pro Phe Phe Leu 
                645                 650                 655


Met Gly Arg Val Leu Tyr Phe His His Tyr Phe Pro Ala Met Leu Phe 
            660                 665                 670


Ser Ser Met Leu Thr Gly Ile Leu Trp Asp Thr Leu Leu Arg Leu Cys 
        675                 680                 685


Ala Trp Gly Leu Ala Ser Trp Pro Leu Ala Arg Gly Ile His Val Ala 
    690                 695                 700


Gly Ile Leu Ser Leu Leu Leu Gly Thr Ala Tyr Ser Phe Tyr Leu Phe 
705                 710                 715                 720


His Pro Leu Ala Tyr Gly Met Val Gly Pro Leu Ala Gln Asp Pro Gln 
                725                 730                 735


Ser Pro Met Ala Gly Leu Arg Trp Leu Asp Ser Trp Asp Phe 
            740                 745                 750


<210>  8484
<211>  2822
<212>  DNA
<213>  Homo sapiens

<400>  8484
cccgggccgc gaccacgctg cccgccccgc cccgagcccg gggccccgcg ctccgctgca     60

gtgaagggcg ttgcatttcc cggggtaccc cgagctgccc tcttgtgact ccttggcggg    120

gcggctggtc agacaaagtg tgcctccggg ccggagggcg acccagagga gggggaagat    180

gccgccggcc acgggcggag gcctggcaga gtccgagctg cgtccccgga ggggccgctg    240

tggcccccag gctgctaggg ccgcaggccg ggacgtggcc gctgaggctg tggcgcgaag    300

ccccaaacgg cctgcttggg gctcacggcg cttcgaggcg gtcggctggt gggccctgct    360

ggccttggtg acgctgctgt ccttcgccac ccgcttccac cgcttggacg agccgccgca    420

catctgttgg gatgagactc actttggaaa aatgggaagt tactatatca accgtacatt    480

tttctttgat gtgcacccgc ccctgggaaa gatgctgata ggtcttgctg gctacctgag    540

tggatatgat ggtacctttt tgttccagaa gcctggggat aaatatgagc atcacagcta    600

catgggaatg agaggattct gtgcattcct tggctcctgg ctggtcccct ttgcctacct    660

cactgtactg gatctgtcca agtccctctc ggcagcactg ctcacagctg ccctcctcac    720

ctttgacacg ggatgcctca ctctgtccca gtacatcctc cttgacccca tcctgatgtt    780

cttcatcatg gctgccatgc tgagcatggt caagtacaac tcttgcgccg acaggccctt    840

ctctgccccc tggtggttct ggctcagcct gactggcgtt agtcttgctg gtgctttagg    900

ggtcaagttt gttggcctct ttatcatcct tcaagtgggg ctgaacacca ttgcagacct    960

ttggtacctg ttcggagacc tcagtctttc attggtgact gtgggaaaac acctgactgc   1020

tcgtgtcctg tgcctcatag tgctgcccct ggctctctat acagccacct ttgctgttca   1080

cttcatggtg ctgagtaaaa gtggccctgg tgacggtttc ttcagttctg ccttccaggc   1140

ccggctttca gggaacaacc tgcacaatgc ttccatccct gaacacctgg cctacggctc   1200

tgtgatcact gtgaagaacc tccggatggc catcggctat ctgcactccc acaggcacct   1260

ctaccccgag ggcattggtg cccgtcagca gcaggtcacc acctatttgc acaaggacta   1320

caacaacctg tggattatca agaaacataa cacaaactca gatcccctag acccttcctt   1380

cccagtggag tttgtaagac atggagacat tattcgacta gaacacaaag aaacttcccg   1440

gaacttgcac agtcactatc atgaggcccc catgacccgg aagcactatc aggtcaccgg   1500

ctatggcata aatggaacag gggactcaaa tgatttctgg cggattgagg tcgtaaacag   1560

gaaatttgga aaccggatca aagtgctgag aagtcgaatt cgcttcatcc atttggtcac   1620

aggttgtgtc ctgggctcct cgggaaaggt tctgcccaag tggggctggg agcagttgga   1680

agttacttgc accccatacc tgaaagaaac cctcaactcc atctggaatg tggaggacca   1740

tatcaatccc aagttgccaa acatcagcct ggatgtgcta cagcccagtt ttcctgagat   1800

cttgctggaa tcccacatgg tcatgatccg ggggaacagt ggcctcaaac ccaaggacaa   1860

tgagttcacg tccaaaccct ggcactggcc tatcaactat cagggcctac gcttctcagg   1920

ggtcaatgac acagatttcc gagtctatct gcttggcaac ccggtggttt ggtggctgaa   1980

tctgttgagc atcgccctct acctcctctc agggagcatc attgctgtag ccatgcagag   2040

aggggcacgg ctgccagcgg aggttgcagg gttgtcccag gtcctgcttc gaggaggcgg   2100

ccaggtcctg ctcggctgga cactccatta cttcccgttt ttcctgatgg gccgggtcct   2160

ctacttccac cactacttcc cagccatgct cttctcaagc atgttgacag gcattctgtg   2220

ggacaccctc ctgcggctct gtgcctgggg cttggcctca tggcccctgg cgaggggcat   2280

acatgtggcg ggaatcctga gcctgctcct gggaactgcc tacagcttct acctcttcca   2340

ccctctggct tacgggatgg ttggtcccct ggcccaggac ccccaaagtc caatggcagg   2400

actaaggtgg ctggactcat gggacttttg aggccactgc aaagattcca gcctgggtcc   2460

aggaacttcc caggagagcc agctgggaag cagtactgga ccatccggcc atgaggaagc   2520

tgcctaagga gcccgaagaa ttctgctgct caccaggacc cagctctggg agtgcagctg   2580

gaatggaacc cagcattgga gagagccggg agagagccgc agctccgtcc acagcaccac   2640

ggagaggaca gcgcctcttg ggctgctccc tcgtgcacag cgcaggggag gatgggtgcc   2700

agagggtggg agtgggtgcg cgtgtgtgta tgtgagggca tgttgtccat atccctgtgg   2760

aatacagacc gtgtaactgg acagctgagt gtcataaact ctaaaatagt ccaggctata   2820

gt                                                                  2822


<210>  8485
<211>  750
<212>  PRT
<213>  Homo sapiens

<400>  8485

Met Pro Pro Ala Thr Gly Gly Gly Leu Ala Glu Ser Glu Leu Arg Pro 
1               5                   10                  15


Arg Arg Gly Arg Cys Gly Pro Gln Ala Ala Arg Ala Ala Gly Arg Asp 
            20                  25                  30


Val Ala Ala Glu Ala Val Ala Arg Ser Pro Lys Arg Pro Ala Trp Gly 
        35                  40                  45


Ser Arg Arg Phe Glu Ala Val Gly Trp Trp Ala Leu Leu Ala Leu Val 
    50                  55                  60


Thr Leu Leu Ser Phe Ala Thr Arg Phe His Arg Leu Asp Glu Pro Pro 
65                  70                  75                  80


His Ile Cys Trp Asp Glu Thr His Phe Gly Lys Met Gly Ser Tyr Tyr 
                85                  90                  95


Ile Asn Arg Thr Phe Phe Phe Asp Val His Pro Pro Leu Gly Lys Met 
            100                 105                 110


Leu Ile Gly Leu Ala Gly Tyr Leu Ser Gly Tyr Asp Gly Thr Phe Leu 
        115                 120                 125


Phe Gln Lys Pro Gly Asp Lys Tyr Glu His His Ser Tyr Met Gly Met 
    130                 135                 140


Arg Gly Phe Cys Ala Phe Leu Gly Ser Trp Leu Val Pro Phe Ala Tyr 
145                 150                 155                 160


Leu Thr Val Leu Asp Leu Ser Lys Ser Leu Ser Ala Ala Leu Leu Thr 
                165                 170                 175


Ala Ala Leu Leu Thr Phe Asp Thr Gly Cys Leu Thr Leu Ser Gln Tyr 
            180                 185                 190


Ile Leu Leu Asp Pro Ile Leu Met Phe Phe Ile Met Ala Ala Met Leu 
        195                 200                 205


Ser Met Val Lys Tyr Asn Ser Cys Ala Asp Arg Pro Phe Ser Ala Pro 
    210                 215                 220


Trp Trp Phe Trp Leu Ser Leu Thr Gly Val Ser Leu Ala Gly Ala Leu 
225                 230                 235                 240


Gly Val Lys Phe Val Gly Leu Phe Ile Ile Leu Gln Val Gly Leu Asn 
                245                 250                 255


Thr Ile Ala Asp Leu Trp Tyr Leu Phe Gly Asp Leu Ser Leu Ser Leu 
            260                 265                 270


Val Thr Val Gly Lys His Leu Thr Ala Arg Val Leu Cys Leu Ile Val 
        275                 280                 285


Leu Pro Leu Ala Leu Tyr Thr Ala Thr Phe Ala Val His Phe Met Val 
    290                 295                 300


Leu Ser Lys Ser Gly Pro Gly Asp Gly Phe Phe Ser Ser Ala Phe Gln 
305                 310                 315                 320


Ala Arg Leu Ser Gly Asn Asn Leu His Asn Ala Ser Ile Pro Glu His 
                325                 330                 335


Leu Ala Tyr Gly Ser Val Ile Thr Val Lys Asn Leu Arg Met Ala Ile 
            340                 345                 350


Gly Tyr Leu His Ser His Arg His Leu Tyr Pro Glu Gly Ile Gly Ala 
        355                 360                 365


Arg Gln Gln Gln Val Thr Thr Tyr Leu His Lys Asp Tyr Asn Asn Leu 
    370                 375                 380


Trp Ile Ile Lys Lys His Asn Thr Asn Ser Asp Pro Leu Asp Pro Ser 
385                 390                 395                 400


Phe Pro Val Glu Phe Val Arg His Gly Asp Ile Ile Arg Leu Glu His 
                405                 410                 415


Lys Glu Thr Ser Arg Asn Leu His Ser His Tyr His Glu Ala Pro Met 
            420                 425                 430


Thr Arg Lys His Tyr Gln Val Thr Gly Tyr Gly Ile Asn Gly Thr Gly 
        435                 440                 445


Asp Ser Asn Asp Phe Trp Arg Ile Glu Val Val Asn Arg Lys Phe Gly 
    450                 455                 460


Asn Arg Ile Lys Val Leu Arg Ser Arg Ile Arg Phe Ile His Leu Val 
465                 470                 475                 480


Thr Gly Cys Val Leu Gly Ser Ser Gly Lys Val Leu Pro Lys Trp Gly 
                485                 490                 495


Trp Glu Gln Leu Glu Val Thr Cys Thr Pro Tyr Leu Lys Glu Thr Leu 
            500                 505                 510


Asn Ser Ile Trp Asn Val Glu Asp His Ile Asn Pro Lys Leu Pro Asn 
        515                 520                 525


Ile Ser Leu Asp Val Leu Gln Pro Ser Phe Pro Glu Ile Leu Leu Glu 
    530                 535                 540


Ser His Met Val Met Ile Arg Gly Asn Ser Gly Leu Lys Pro Lys Asp 
545                 550                 555                 560


Asn Glu Phe Thr Ser Lys Pro Trp His Trp Pro Ile Asn Tyr Gln Gly 
                565                 570                 575


Leu Arg Phe Ser Gly Val Asn Asp Thr Asp Phe Arg Val Tyr Leu Leu 
            580                 585                 590


Gly Asn Pro Val Val Trp Trp Leu Asn Leu Leu Ser Ile Ala Leu Tyr 
        595                 600                 605


Leu Leu Ser Gly Ser Ile Ile Ala Val Ala Met Gln Arg Gly Ala Arg 
    610                 615                 620


Leu Pro Ala Glu Val Ala Gly Leu Ser Gln Val Leu Leu Arg Gly Gly 
625                 630                 635                 640


Gly Gln Val Leu Leu Gly Trp Thr Leu His Tyr Phe Pro Phe Phe Leu 
                645                 650                 655


Met Gly Arg Val Leu Tyr Phe His His Tyr Phe Pro Ala Met Leu Phe 
            660                 665                 670


Ser Ser Met Leu Thr Gly Ile Leu Trp Asp Thr Leu Leu Arg Leu Cys 
        675                 680                 685


Ala Trp Gly Leu Ala Ser Trp Pro Leu Ala Arg Gly Ile His Val Ala 
    690                 695                 700


Gly Ile Leu Ser Leu Leu Leu Gly Thr Ala Tyr Ser Phe Tyr Leu Phe 
705                 710                 715                 720


His Pro Leu Ala Tyr Gly Met Val Gly Pro Leu Ala Gln Asp Pro Gln 
                725                 730                 735


Ser Pro Met Ala Gly Leu Arg Trp Leu Asp Ser Trp Asp Phe 
            740                 745                 750


<210>  8486
<211>  556
<212>  DNA
<213>  Homo sapiens

<400>  8486
aggctgggcc ctgaccagag ctctcgagcc ccagctgctc ctctccagtt tctgtagcgt     60

ggtttgggtt ggtccaatga ggtgatatga catattcaag gtcacacagc aaggaagggg    120

cagagctgga ccagagcctg gaatctctgc ccgctccttg tcttctgact gggctgtgct    180

gcttgggccc agggttgtcc caggtcctgc ttcgaggagg cggccaggtc ctgctcggct    240

ggacactcca ttacttcccg tttttcctga tgggccgggt cctctacttc caccactact    300

tcccagccat gctcttctca agcatgttga caggcattct gtgggacacc ctcctgcggc    360

tctgtgcctg gggcttggcc tcatggcccc tggcgagggg catacatgtg gcgggaatcc    420

tgagcctgct cctgggaact gcctacaggt gagcatctct gcacctcaca tgccctccca    480

gtgtgggctc agcagtgcct cagccctgat gcattcgaga atcccctgcg gtgcttttaa    540

caccaccagt gcccat                                                    556


<210>  8487
<211>  121
<212>  PRT
<213>  Homo sapiens

<400>  8487

Met Thr Tyr Ser Arg Ser His Ser Lys Glu Gly Ala Glu Leu Asp Gln 
1               5                   10                  15


Ser Leu Glu Ser Leu Pro Ala Pro Cys Leu Leu Thr Gly Leu Cys Cys 
            20                  25                  30


Leu Gly Pro Gly Leu Ser Gln Val Leu Leu Arg Gly Gly Gly Gln Val 
        35                  40                  45


Leu Leu Gly Trp Thr Leu His Tyr Phe Pro Phe Phe Leu Met Gly Arg 
    50                  55                  60


Val Leu Tyr Phe His His Tyr Phe Pro Ala Met Leu Phe Ser Ser Met 
65                  70                  75                  80


Leu Thr Gly Ile Leu Trp Asp Thr Leu Leu Arg Leu Cys Ala Trp Gly 
                85                  90                  95


Leu Ala Ser Trp Pro Leu Ala Arg Gly Ile His Val Ala Gly Ile Leu 
            100                 105                 110


Ser Leu Leu Leu Gly Thr Ala Tyr Arg 
        115                 120


<210>  8488
<211>  724
<212>  DNA
<213>  Homo sapiens

<400>  8488
aatcaactaa ttcaacaact ctttatcaag tatgccagga accacatggg gccctgtgga     60

catattggcg aggagacaga cttggtcccc atcccgacag cagctgctcc aggcgtccag    120

aatgatttat tcctcattcc caggcccttc aaagggccac agtgactcgg gggctgtgca    180

gctgtccctt atgcctaata ggagagcagc atttgagcca gtaccacagt gaaaagcaat    240

ggtgctggga gctgttggag caccaagcag gtgaaacctt gttgtctatt tcctttgcat    300

ttcttagaat gcctgatgag ttcttcatac agctaagtaa atgatcaaga attgggccaa    360

gctttcttct gtctcctcaa cagttgtgaa cttgtcagca aggctgcatt tggattctgg    420

tgggaatgtg gacaccatgg acagactgag gaaagaatgt atgacaaagg cttttctcct    480

gcattttttt cccctagtgc caaacatcag cctggatgtg ctacagccca gttttcctga    540

gatcttgctg gaatcccaca tggtcatgat ccgggggaac agtggcctca aacccaagga    600

caatgagttc acgtccaaac cctggcactg gcctatcaac tatcaggtag gatccaaggc    660

tggggctcct cccaggaaat ggagccaaga acaagagcag ggagaccggt ggaggcgggg    720

gtgg                                                                 724


<210>  8489
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  8489

Met Ile Lys Asn Trp Ala Lys Leu Ser Ser Val Ser Ser Thr Val Val 
1               5                   10                  15


Asn Leu Ser Ala Arg Leu His Leu Asp Ser Gly Gly Asn Val Asp Thr 
            20                  25                  30


Met Asp Arg Leu Arg Lys Glu Cys Met Thr Lys Ala Phe Leu Leu His 
        35                  40                  45


Phe Phe Pro Leu Val Pro Asn Ile Ser Leu Asp Val Leu Gln Pro Ser 
    50                  55                  60


Phe Pro Glu Ile Leu Leu Glu Ser His Met Val Met Ile Arg Gly Asn 
65                  70                  75                  80


Ser Gly Leu Lys Pro Lys Asp Asn Glu Phe Thr Ser Lys Pro Trp His 
                85                  90                  95


Trp Pro Ile Asn Tyr Gln Val Gly Ser Lys Ala Gly Ala Pro Pro Arg 
            100                 105                 110


Lys Trp Ser Gln Glu Gln Glu Gln Gly Asp Arg Trp Arg Arg Gly 
        115                 120                 125


<210>  8490
<211>  1346
<212>  DNA
<213>  Homo sapiens

<400>  8490
ctgtcgccta ggctggagtg cagtggcgcg atctcggctc actgcaagct ctgcctcccg     60

ggttcacgcc tcagcctccc tagtagctgg gattacaggc acgtgccacc atgcctggct    120

aattttttgt atttttagta gagacagggt tttaccatgt tagccaggat ggtctccatc    180

tcctgacttc gtgatccgcc tgcctcggcc tcccaaagtg ctgggattac aggtgtgagc    240

caccgtaccc ggccagaaga aaactcttac tacaaacctt tccatattat gagaaaacat    300

cttgtccttt taaaataaat agaaactcaa gatacagatt gggatgagac tcactttgga    360

aaaatgggaa gttactatat caaccgtaca tttttctttg atgtgcaccc gcccctggga    420

aagatgctga taggtcttgc tggctacctg agtggatatg atggtacctt tttgttccag    480

aagcctgggg ataaatatga gcatcacagc tacatgggaa tgagaggagt aaggcttcct    540

gacttgaaat ggactgactg aaccctgggg ccacactaaa ccagaaatgt tatagttagc    600

agccctggcg tggtggcagg tgcaaataaa gggactttgg gtggtgagga gaggggagga    660

tgatcagacc ctcccctgtg gtgtagatac tcagaactga ggtgaggaag aagggaagag    720

gaggctgcaa ataatacaga gatgacatag atagaagcag gcacgcattg tcacctgctg    780

ccctgccccg gtatactgtc agacctcagg ttggagaaca gcctggaacc cgggcaatca    840

ggagtctcct gcagccccag cagtgcctcc atgcactggc acgctgcctg ctcctcccct    900

cacagccaca gctgctggag tgttgcctac atctcagagc cttttctgaa gattttggca    960

tccccacacc ctgtcaccat gttcctgtgt ctttccccat gaaggtttca ggcacacaga   1020

aagagttttc cagccttatt tgaagggagg ccaaatgtct gctgcagtcc ctctgtgtcc   1080

tgatttacag caccagcctt gatggaacat ggcagggcct taacacccaa ctctttggga   1140

accttgaacg tgtggctgaa tgaagccagc agaagctgac ctccagtgtg gacctctcag   1200

agaagtttgc atttacaagc ccctttcctt gaggatttca cagcatttaa ataaatggct   1260

gtgtgcttat ttggcctcat cgttagatga tttgcatggc tatatcgtgg tatattaaac   1320

aaggagtata tcctaccctc aagttc                                        1346


<210>  8491
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  8491

Met Gly Ser Tyr Tyr Ile Asn Arg Thr Phe Phe Phe Asp Val His Pro 
1               5                   10                  15


Pro Leu Gly Lys Met Leu Ile Gly Leu Ala Gly Tyr Leu Ser Gly Tyr 
            20                  25                  30


Asp Gly Thr Phe Leu Phe Gln Lys Pro Gly Asp Lys Tyr Glu His His 
        35                  40                  45


Ser Tyr Met Gly Met Arg Gly Val Arg Leu Pro Asp Leu Lys Trp Thr 
    50                  55                  60


Asp 
65


<210>  8492
<211>  1230
<212>  DNA
<213>  Homo sapiens

<400>  8492
gcatgtcggg accgggaggg ccggccggcc cggggcgggg gggactgggc aggaggggtc     60

gggctcaggg aactgcaact cccagcagcc cccaggtacg gggcgtggcg ggagagctgg    120

gcgagccaga ggcgaccgga aggatctttc tagtccagcc cctcgcttta cccggacgaa    180

agacacgggc ctgattcgtc gagtctcact gagccttagt cgtcggcagg tcccaggcgc    240

gaagtttctc ggcctggagg agggggtcgc gcgaagtgcc agatgcaggc ggggaagccc    300

atcctctatt cctatttccg aagctcctgc tcatggagag ttcgaattgc tctggccttg    360

aaaggcatcg actacgagac ggtgcccatc aatctcataa aggatggggg ccaacagttt    420

tctaaggact tccaggcact gaatcctatg aagcaggtgc caaccctgaa gattgatgga    480

atcaccattc accagtcact ggccatcatt gagtatctag aggagatgcg tcccactccg    540

cgacttctgc ctcaggaccc aaagaagagg gccagcgtgc gtatgatttc tgacctcatc    600

gctggtggca tccagcccct gcagaacctg tctgtcctga agcaagtggg agaggagatg    660

cagctgacct gggcccagaa cgccatcact tgtggcttta acgccctgga gcagatccta    720

cagagcacag cgggcatata ctgtgtagga gacgaggtga ccatggctga tctgtgcttg    780

gtgcctcagg tggcaaatgc tgaaagattc aaggtggatc tcacccccta ccctaccatc    840

agctccatca acaagaggct gctggtcttg gaggccttcc aggtgtctca cccctgccgg    900

cagccagata cacccactga gctgagggcc tagctcccaa atcctgcccc gttggcacag    960

ggccacagga gcagaagctg ggtgggctga agaggcctgg aaacgagagt cttaattgag   1020

gagatgggag actcgaactc tagccctgga tctgccttcc tgctgaaact tgttccacct   1080

cagtcccctc atctgtcaca cgcatgtggg gtggagtagg gagatgcggg gagcagggtg   1140

ggcaggaata ctgttatcta tgtgacgggg cagtcgtgag gctgagatga gaatgcggat   1200

taaaatgcct ggcgtgctca ccgtaacacc                                    1230


<210>  8493
<211>  216
<212>  PRT
<213>  Homo sapiens

<400>  8493

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Val Pro Thr Leu Lys Ile 
    50                  55                  60


Asp Gly Ile Thr Ile His Gln Ser Leu Ala Ile Ile Glu Tyr Leu Glu 
65                  70                  75                  80


Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln Asp Pro Lys Lys Arg 
                85                  90                  95


Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala Gly Gly Ile Gln Pro 
            100                 105                 110


Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met Gln Leu 
        115                 120                 125


Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu Glu Gln 
    130                 135                 140


Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu Val Thr 
145                 150                 155                 160


Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe 
                165                 170                 175


Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg 
            180                 185                 190


Leu Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro 
        195                 200                 205


Asp Thr Pro Thr Glu Leu Arg Ala 
    210                 215


<210>  8494
<211>  1337
<212>  DNA
<213>  Homo sapiens

<400>  8494
gcatgtcggg accgggaggg ccggccggcc cggggcgggg gggactgggc aggaggggtc     60

gggctcaggg aactgcaact cccagcagcc cccaggtacg gggcgtggcg ggagagctgg    120

gcgagccaga ggcgaccgga aggatctttc tagtccagcc cctcgcttta cccggacgaa    180

agacacgggc ctgattcgtc gagtctcact gagccttagt cgtcggcagg tcccaggcgc    240

gaagtttctc ggcctggagg agggggtcgc gcgaagtgcc agatgcaggc ggggaagccc    300

atcctctatt cctatttccg aagctcctgc tcatggagag ttcgaattgc tctggccttg    360

aaaggcatcg actacgagac ggtgcccatc aatctcataa aggatggggg ccaacagttt    420

tctaaggact tccaggcact gaatcctatg aagcaggtgc caaccctgaa gattgatgga    480

atcaccattc accagtcact ggccatcatt gagtatctag aggagatgcg tcccactccg    540

cgacttctgc ctcaggaccc aaagaagagg gccagcgtgc gtatgatttc tgacctcatc    600

gctggtggca tccagcccct gcagaacctg tctgtcctga agcaagtggg agaggagatg    660

cagctgacct gggcccagaa cgccatcact tgtggcttta acgccctgga gcagatccta    720

cagagcacag cgggcatata ctgtgtagga gacgaggtga ccatggctga tctgtgcttg    780

gtgcctcagg tggcaaatgc tgaaagattc aaggtggatc tcacccccta ccctaccatc    840

agctccatca acaagaggct gctggtcttg gaggccttcc aggtgtctca cccctgccgg    900

cagccagata cacccactga gctgagggcc tagctcccaa atcctgcccc gttggcacag    960

ggccacagga gcagaagctg ggtgggctga agaggcctgg aaacgagagt cttaattgag   1020

gagatgggag actcgaactc tagccctgga tctgccttcc tgctgaaact tgttccacct   1080

cagtcccctc atctgtcaca cgcatgtggg gtggagtagg gagatgcggg gagcagggtg   1140

ggcaggaata ctgttatcta tgtgacgggg cagtcgtgag gctgagatga gaatgcggat   1200

taaaatgcct ggcgtgctca ccgtaacacc acggggaagg ctgtgtgcct tttctcatcc   1260

gcttttgttg tgtgtgactc caaagaatgc ccgcgctgaa atttggcgtg aattaaactg   1320

aagcccaggc ctctacc                                                  1337


<210>  8495
<211>  216
<212>  PRT
<213>  Homo sapiens

<400>  8495

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Val Pro Thr Leu Lys Ile 
    50                  55                  60


Asp Gly Ile Thr Ile His Gln Ser Leu Ala Ile Ile Glu Tyr Leu Glu 
65                  70                  75                  80


Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln Asp Pro Lys Lys Arg 
                85                  90                  95


Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala Gly Gly Ile Gln Pro 
            100                 105                 110


Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met Gln Leu 
        115                 120                 125


Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu Glu Gln 
    130                 135                 140


Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu Val Thr 
145                 150                 155                 160


Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe 
                165                 170                 175


Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg 
            180                 185                 190


Leu Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro 
        195                 200                 205


Asp Thr Pro Thr Glu Leu Arg Ala 
    210                 215


<210>  8496
<211>  1085
<212>  DNA
<213>  Homo sapiens

<400>  8496
gccagaggcg accggaagga tctttctagt ccagcccctc gctttacccg gacgaaagac     60

acgggcctga ttcgtcgagt ctcactgagc cttagtcgtc ggcaggtccc aggcgcgaag    120

tttctcggcc tggaggaggg ggtcgcgcga agtgccagat gcaggcgggg aagcccatcc    180

tctattccta tttccgaagc tcctgctcat ggagagttcg aattgctctg gccttgaaag    240

gcatcgacta cgagacggtg cccatcaatc tcataaagga tgggggccaa cagttttcta    300

aggacttcca ggcactgaat cctatgaagc aggtgccaac cctgaagatt gatggaatca    360

ccattcacca gtcaaacctg tctgtcctga agcaagtggg agaggagatg cagctgacct    420

gggcccagaa cgccatcact tgtggcttta acgccctgga gcagatccta cagagcacag    480

cgggcatata ctgtgtagga gacgaggtga ccatggctga tctgtgcttg gtgcctcagg    540

tggcaaatgc tgaaagattc aaggtggatc tcacccccta ccctaccatc agctccatca    600

acaagaggct gctggtcttg gaggccttcc aggtgtctca cccctgccgg cagccagata    660

cacccactga gctgagggcc tagctcccaa atcctgcccc gttggcacag ggccacagga    720

gcagaagctg ggtgggctga agaggcctgg aaacgagagt cttaattgag gagatgggag    780

actcgaactc tagccctgga tctgccttcc tgctgaaact tgttccacct cagtcccctc    840

atctgtcaca cgcatgtggg gtggagtagg gagatgcggg gagcagggtg ggcaggaata    900

ctgttatcta tgtgacgggg cagtcgtgag gctgagatga gaatgcggat taaaatgcct    960

ggcgtgctca ccgtaacacc acggggaagg ctgtgtgcct tttctcatcc gcttttgttg   1020

tgtgtgactc caaagaatgc ccgcgctgaa atttggcgtg aattaaactg aagcccaggc   1080

ctcta                                                               1085


<210>  8497
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  8497

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Val Pro Thr Leu Lys Ile 
    50                  55                  60


Asp Gly Ile Thr Ile His Gln Ser Asn Leu Ser Val Leu Lys Gln Val 
65                  70                  75                  80


Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly 
                85                  90                  95


Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys 
            100                 105                 110


Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val 
        115                 120                 125


Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile 
    130                 135                 140


Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser 
145                 150                 155                 160


His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
                165                 170


<210>  8498
<211>  966
<212>  DNA
<213>  Homo sapiens

<400>  8498
gaaggatctt tctagtccag cccctcgctt tacccggacg aaagacacgg gcctgattcg     60

tcgagtctca ctgagcctta gtcgtcggca ggtcccaggc gcgaagtttc tcggcctgga    120

ggagggggtc gcgcgaagtg ccagatgcag gcggggaagc ccatcctcta ttcctatttc    180

cgaagctcct gctcatggag agttcgaatt gctctggcct tgaaaggcat cgactacgag    240

acggtgccca tcaatctcat aaaggatggg ggccaacagt tttctaagga cttccaggca    300

ctgaatccta tgaagcaggt gccaaccctg aagattgatg gaatcaccat tcaccagtca    360

aacctgtctg tcctgaagca agtgggagag gagatgcagc tgacctgggc ccagaacgcc    420

atcacttgtg gctttaacgc cctggagcag atcctacaga gcacagcggg catatactgt    480

gtaggagacg aggtgaccat ggctgatctg tgcttggtgc ctcaggtggc aaatgctgaa    540

agattcaagg tggatctcac cccctaccct accatcagct ccatcaacaa gaggctgctg    600

gtcttggagg ccttccaggt gtctcacccc tgccggcagc cagatacacc cactgagctg    660

agggcctagc tcccaaatcc tgccccgttg gcacagggcc acaggagcag aagctgggtg    720

ggctgaagag gcctggaaac gagagtctta attgaggaga tgggagactc gaactctagc    780

cctggatctg ccttcctgct gaaacttgtt ccacctcagt cccctcatct gtcacacgca    840

tgtggggtgg agtagggaga tgcggggagc agggtgggca ggaatactgt tatctatgtg    900

acggggcagt cgtgaggctg agatgagaat gcggattaaa atgcctggcg tgctcaccgt    960

aacacc                                                               966


<210>  8499
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  8499

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Val Pro Thr Leu Lys Ile 
    50                  55                  60


Asp Gly Ile Thr Ile His Gln Ser Asn Leu Ser Val Leu Lys Gln Val 
65                  70                  75                  80


Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly 
                85                  90                  95


Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys 
            100                 105                 110


Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val 
        115                 120                 125


Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile 
    130                 135                 140


Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser 
145                 150                 155                 160


His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
                165                 170


<210>  8500
<211>  563
<212>  DNA
<213>  Homo sapiens

<400>  8500
ctttctagtc cagcccctcg ctttacccgg acgaaagaca cgggcctgat tcgtcgagtc     60

tcactgagcc ttagtcgtcg gcaggtccca ggcgcgaagt ttctcggcct ggaggagggg    120

gtcgcgcgaa gtgccagatg caggcgggga agcccatcct ctattcctat ttccgaagct    180

cctgctcatg gagagttcga attggtaaga gatgtgcctc ctccaggatg agtgctggag    240

tggggtggac tggggcggat aagcccgggt gcaaagctgg cctgggatgg aagggttgct    300

ctgtcagaga ggacctcacc cccagcaacc agcatccccc ggctcctaga acccccatcc    360

ctgcatggca tctccacccc ggaaacacag ggtgagggtg ggaggaaggg ggttgttttt    420

tcccttggga ctgacacttc tcccaacact gctctccaaa gccccttggc aaccatgttt    480

aaagcagggt cacaaaatcc acatgcccct ggtaactggc aggggaacag ctggcccttc    540

tcagttctta ttttatttga act                                            563


<210>  8501
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  8501

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Gly Lys Arg Cys Ala Ser Ser Arg Met Ser 
            20                  25                  30


Ala Gly Val Gly Trp Thr Gly Ala Asp Lys Pro Gly Cys Lys Ala Gly 
        35                  40                  45


Leu Gly Trp Lys Gly Cys Ser Val Arg Glu Asp Leu Thr Pro Ser Asn 
    50                  55                  60


Gln His Pro Pro Ala Pro Arg Thr Pro Ile Pro Ala Trp His Leu His 
65                  70                  75                  80


Pro Gly Asn Thr Gly 
                85


<210>  8502
<211>  829
<212>  DNA
<213>  Homo sapiens

<400>  8502
ctagtccagc ccctcgcttt acccggacga aagacacggg cctgattcgt cgagtctcac     60

tgagccttag tcgtcggcag gtcccaggcg cgaagtttct cggcctggag gagggggtcg    120

cgcgaagtgc cagatgcagg cggggaagcc catcctctat tcctatttcc gaagctcctg    180

ctcatggaga gttcgaattg ctctggcctt gaaaggcatc gactacgaga cggtgcccat    240

caatctcata aaggatgggg gccaacagtt ttctaaggac ttccaggcac tgaatcctat    300

gaagcaggtg ccaaccctga agattgatgg aatcaccatt caccagtcac tggccatcat    360

tgagtatcta gaggagatgc gtcccactcc gcgacttctg cctcaggacc caaagaagag    420

ggccagcgtg cgtatgattt ctgacctcat cgctggtggc atccagcccc tgcagaacct    480

gtctgtcctg aagcaagtgg gagaggagat gcagctgacc tgggcccaga acgccatcac    540

ttgtggcttt aacggtgagt cctcacctct gtgagctgcc ccacagtggc ctcttagagg    600

tatggccctc gcacacaggg gcctgggtat ctgaaccagc ctcccaggct gctttgggcc    660

tgacagttgc atggatgagg gcaggactgg ggaggcaatg ggctgggtgg gcatccagac    720

cttagctcca gcacttctgg gaacctcggt ccctgagccc acagcccttc atagctggat    780

ggcccaactt cagcttcact gcctactcca gctgggaaac caaggccag                829


<210>  8503
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  8503

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Val Pro Thr Leu Lys Ile 
    50                  55                  60


Asp Gly Ile Thr Ile His Gln Ser Leu Ala Ile Ile Glu Tyr Leu Glu 
65                  70                  75                  80


Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln Asp Pro Lys Lys Arg 
                85                  90                  95


Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala Gly Gly Ile Gln Pro 
            100                 105                 110


Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met Gln Leu 
        115                 120                 125


Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Gly Glu Ser Ser 
    130                 135                 140


Pro Leu 
145


<210>  8504
<211>  1039
<212>  DNA
<213>  Homo sapiens

<400>  8504
ctagtccagc ccctcgcttt acccggacga aagacacggg cctgattcgt cgagtctcac     60

tgagccttag tcgtcggcag gtcccaggcg cgaagtttct cggcctggag gagggggtcg    120

cgcgaagtgc cagatgcagg cggggaagcc catcctctat tcctatttcc gaagctcctg    180

ctcatggaga gttcgaattg ctctggcctt gaaaggcatc gactacgaga cggtgcccat    240

caatctcata aaggatgggg gccaacagtt ttctaaggac ttccaggcac tgaatcctat    300

gaagcagctg gccatcattg agtatctaga ggagatgcgt cccactccgc gacttctgcc    360

tcaggaccca aagaagaggg ccagcgtgcg tatgatttct gacctcatcg ctggtggcat    420

ccagcccctg cagaacctgt ctgtcctgaa gcaagtggga gaggagatgc agctgacctg    480

ggcccagaac gccatcactt gtggctttaa cgccctggag cagatcctac agagcacagc    540

gggcatatac tgtgtaggag acgaggtgac catggctgat ctgtgcttgg tgcctcaggt    600

ggcaaatgct gaaagattca aggtggatct caccccctac cctaccatca gctccatcaa    660

caagaggctg ctggtcttgg aggccttcca ggtgtctcac ccctgccggc agccagatac    720

acccactgag ctgagggcct agctcccaaa tcctgccccg ttggcacagg gccacaggag    780

cagaagctgg gtgggctgaa gaggcctgga aacgagagtc ttaattgagg agatgggaga    840

ctcgaactct agccctggat ctgccttcct gctgaaactt gttccacctc agtcccctca    900

tctgtcacac gcatgtgggg tggagtaggg agatgcgggg agcagggtgg gcaggaatac    960

tgttatctat gtgacggggc agtcgtgagg ctgagatgag aatgcggatt aaaatgcctg   1020

gcgtgctcac cgtaacacc                                                1039


<210>  8505
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  8505

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Leu Ala Ile Ile Glu Tyr 
    50                  55                  60


Leu Glu Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln Asp Pro Lys 
65                  70                  75                  80


Lys Arg Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala Gly Gly Ile 
                85                  90                  95


Gln Pro Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met 
            100                 105                 110


Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu 
        115                 120                 125


Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu 
    130                 135                 140


Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu 
145                 150                 155                 160


Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn 
                165                 170                 175


Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg 
            180                 185                 190


Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
        195                 200


<210>  8506
<211>  1144
<212>  DNA
<213>  Homo sapiens

<400>  8506
ctagtccagc ccctcgcttt acccggacga aagacacggg cctgattcgt cgagtctcac     60

tgagccttag tcgtcggcag gtcccaggcg cgaagtttct cggcctggag gagggggtcg    120

cgcgaagtgc cagatgcagg cggggaagcc catcctctat tcctatttcc gaagctcctg    180

ctcatggaga gttcgaattg ctctggcctt gaaaggcatc gactacgaga cggtgcccat    240

caatctcata aaggatgggg gccaacagtt ttctaaggac ttccaggcac tgaatcctat    300

gaagcagctg gccatcattg agtatctaga ggagatgcgt cccactccgc gacttctgcc    360

tcaggaccca aagaagaggg ccagcgtgcg tatgatttct gacctcatcg ctggtggcat    420

ccagcccctg cagaacctgt ctgtcctgaa gcaagtggga gaggagatgc agctgacctg    480

ggcccagaac gccatcactt gtggctttaa cgccctggag cagatcctac agagcacagc    540

gggcatatac tgtgtaggag acgaggtgac catggctgat ctgtgcttgg tgcctcaggt    600

ggcaaatgct gaaagattca aggtggatct caccccctac cctaccatca gctccatcaa    660

caagaggctg ctggtcttgg aggccttcca ggtgtctcac ccctgccggc agccagatac    720

acccactgag ctgagggcct agctcccaaa tcctgccccg ttggcacagg gccacaggag    780

cagaagctgg gtgggctgaa gaggcctgga aacgagagtc ttaattgagg agatgggaga    840

ctcgaactct agccctggat ctgccttcct gctgaaactt gttccacctc agtcccctca    900

tctgtcacac gcatgtgggg tggagtaggg agatgcgggg agcagggtgg gcaggaatac    960

tgttatctat gtgacggggc agtcgtgagg ctgagatgag aatgcggatt aaaatgcctg   1020

gcgtgctcac cgtaacacca cggggaaggc tgtgtgcctt ttctcatccg cttttgttgt   1080

gtgtgactcc aaagaatgcc cgcgctgaaa tttggcgtga attaaactga agcccaggcc   1140

tcta                                                                1144


<210>  8507
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  8507

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Phe Ser Lys 
        35                  40                  45


Asp Phe Gln Ala Leu Asn Pro Met Lys Gln Leu Ala Ile Ile Glu Tyr 
    50                  55                  60


Leu Glu Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln Asp Pro Lys 
65                  70                  75                  80


Lys Arg Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala Gly Gly Ile 
                85                  90                  95


Gln Pro Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met 
            100                 105                 110


Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu 
        115                 120                 125


Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu 
    130                 135                 140


Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu 
145                 150                 155                 160


Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn 
                165                 170                 175


Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg 
            180                 185                 190


Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
        195                 200


<210>  8508
<211>  998
<212>  DNA
<213>  Homo sapiens

<400>  8508
agtccagccc ctcgctttac ccggacgaaa gacacgggcc tgattcgtcg agtctcactg     60

agccttagtc gtcggcaggt cccaggcgcg aagtttctcg gcctggagga gggggtcgcg    120

cgaagtgcca gatgcaggcg gggaagccca tcctctattc ctatttccga agctcctgct    180

catggagagt tcgaattgct ctggccttga aaggcatcga ctacgagacg gtgcccatca    240

atctcataaa ggatgggggc caacagctgg ccatcattga gtatctagag gagatgcgtc    300

ccactccgcg acttctgcct caggacccaa agaagagggc cagcgtgcgt atgatttctg    360

acctcatcgc tggtggcatc cagcccctgc agaacctgtc tgtcctgaag caagtgggag    420

aggagatgca gctgacctgg gcccagaacg ccatcacttg tggctttaac gccctggagc    480

agatcctaca gagcacagcg ggcatatact gtgtaggaga cgaggtgacc atggctgatc    540

tgtgcttggt gcctcaggtg gcaaatgctg aaagattcaa ggtggatctc accccctacc    600

ctaccatcag ctccatcaac aagaggctgc tggtcttgga ggccttccag gtgtctcacc    660

cctgccggca gccagataca cccactgagc tgagggccta gctcccaaat cctgccccgt    720

tggcacaggg ccacaggagc agaagctggg tgggctgaag aggcctggaa acgagagtct    780

taattgagga gatgggagac tcgaactcta gccctggatc tgccttcctg ctgaaacttg    840

ttccacctca gtcccctcat ctgtcacacg catgtggggt ggagtaggga gatgcgggga    900

gcagggtggg caggaatact gttatctatg tgacggggca gtcgtgaggc tgagatgaga    960

atgcggatta aaatgcctgg cgtgctcacc gtaacacc                            998


<210>  8509
<211>  189
<212>  PRT
<213>  Homo sapiens

<400>  8509

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Leu Ala Ile 
        35                  40                  45


Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln 
    50                  55                  60


Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala 
65                  70                  75                  80


Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly 
                85                  90                  95


Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe 
            100                 105                 110


Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val 
        115                 120                 125


Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala 
    130                 135                 140


Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser 
145                 150                 155                 160


Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser His 
                165                 170                 175


Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
            180                 185


<210>  8510
<211>  1027
<212>  DNA
<213>  Homo sapiens

<400>  8510
agtccagccc ctcgctttac ccggacgaaa gacacgggcc tgattcgtcg agtctcactg     60

agccttagtc gtcggcaggt cccaggcgcg aagtttctcg gcctggagga gggggtcgcg    120

cgaagtgcca gatgcaggcg gggaagctct ggccttgaaa ggcatcgact acgagacggt    180

gcccatcaat ctcataaagg atgggggcca acagttttct aaggacttcc aggcactgaa    240

tcctatgaag caggtgccaa ccctgaagat tgatggaatc accattcacc agtcactggc    300

catcattgag tatctagagg agatgcgtcc cactccgcga cttctgcctc aggacccaaa    360

gaagagggcc agcgtgcgta tgatttctga cctcatcgct ggtggcatcc agcccctgca    420

gaacctgtct gtcctgaagc aagtgggaga ggagatgcag ctgacctggg cccagaacgc    480

catcacttgt ggctttaacg ccctggagca gatcctacag agcacagcgg gcatatactg    540

tgtaggagac gaggtgacca tggctgatct gtgcttggtg cctcaggtgg caaatgctga    600

aagattcaag gtggatctca ccccctaccc taccatcagc tccatcaaca agaggctgct    660

ggtcttggag gccttccagg tgtctcaccc ctgccggcag ccagatacac ccactgagct    720

gagggcctag ctcccaaatc ctgccccgtt ggcacagggc cacaggagca gaagctgggt    780

gggctgaaga ggcctggaaa cgagagtctt aattgaggag atgggagact cgaactctag    840

ccctggatct gccttcctgc tgaaacttgt tccacctcag tcccctcatc tgtcacacgc    900

atgtggggtg gagtagggag atgcggggag cagggtgggc aggaatactg ttatctatgt    960

gacggggcag tcgtgaggct gagatgagaa tgcggattaa aatgcctggc gtgctcaccg   1020

taacacc                                                             1027


<210>  8511
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  8511

Met Lys Gln Val Pro Thr Leu Lys Ile Asp Gly Ile Thr Ile His Gln 
1               5                   10                  15


Ser Leu Ala Ile Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg 
            20                  25                  30


Leu Leu Pro Gln Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser 
        35                  40                  45


Asp Leu Ile Ala Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu 
    50                  55                  60


Lys Gln Val Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile 
65                  70                  75                  80


Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly 
                85                  90                  95


Ile Tyr Cys Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val 
            100                 105                 110


Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr 
        115                 120                 125


Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe 
    130                 135                 140


Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg 
145                 150                 155                 160


Ala 



<210>  8512
<211>  1103
<212>  DNA
<213>  Homo sapiens

<400>  8512
agtccagccc ctcgctttac ccggacgaaa gacacgggcc tgattcgtcg agtctcactg     60

agccttagtc gtcggcaggt cccaggcgcg aagtttctcg gcctggagga gggggtcgcg    120

cgaagtgcca gatgcaggcg gggaagccca tcctctattc ctatttccga agctcctgct    180

catggagagt tcgaattgct ctggccttga aaggcatcga ctacgagacg gtgcccatca    240

atctcataaa ggatgggggc caacagctgg ccatcattga gtatctagag gagatgcgtc    300

ccactccgcg acttctgcct caggacccaa agaagagggc cagcgtgcgt atgatttctg    360

acctcatcgc tggtggcatc cagcccctgc agaacctgtc tgtcctgaag caagtgggag    420

aggagatgca gctgacctgg gcccagaacg ccatcacttg tggctttaac gccctggagc    480

agatcctaca gagcacagcg ggcatatact gtgtaggaga cgaggtgacc atggctgatc    540

tgtgcttggt gcctcaggtg gcaaatgctg aaagattcaa ggtggatctc accccctacc    600

ctaccatcag ctccatcaac aagaggctgc tggtcttgga ggccttccag gtgtctcacc    660

cctgccggca gccagataca cccactgagc tgagggccta gctcccaaat cctgccccgt    720

tggcacaggg ccacaggagc agaagctggg tgggctgaag aggcctggaa acgagagtct    780

taattgagga gatgggagac tcgaactcta gccctggatc tgccttcctg ctgaaacttg    840

ttccacctca gtcccctcat ctgtcacacg catgtggggt ggagtaggga gatgcgggga    900

gcagggtggg caggaatact gttatctatg tgacggggca gtcgtgaggc tgagatgaga    960

atgcggatta aaatgcctgg cgtgctcacc gtaacaccac ggggaaggct gtgtgccttt   1020

tctcatccgc ttttgttgtg tgtgactcca aagaatgccc gcgctgaaat ttggcgtgaa   1080

ttaaactgaa gcccaggcct cta                                           1103


<210>  8513
<211>  189
<212>  PRT
<213>  Homo sapiens

<400>  8513

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Leu Ala Ile 
        35                  40                  45


Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg Leu Leu Pro Gln 
    50                  55                  60


Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser Asp Leu Ile Ala 
65                  70                  75                  80


Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu Lys Gln Val Gly 
                85                  90                  95


Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe 
            100                 105                 110


Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val 
        115                 120                 125


Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val Pro Gln Val Ala 
    130                 135                 140


Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser 
145                 150                 155                 160


Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe Gln Val Ser His 
                165                 170                 175


Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg Ala 
            180                 185


<210>  8514
<211>  1132
<212>  DNA
<213>  Homo sapiens

<400>  8514
agtccagccc ctcgctttac ccggacgaaa gacacgggcc tgattcgtcg agtctcactg     60

agccttagtc gtcggcaggt cccaggcgcg aagtttctcg gcctggagga gggggtcgcg    120

cgaagtgcca gatgcaggcg gggaagctct ggccttgaaa ggcatcgact acgagacggt    180

gcccatcaat ctcataaagg atgggggcca acagttttct aaggacttcc aggcactgaa    240

tcctatgaag caggtgccaa ccctgaagat tgatggaatc accattcacc agtcactggc    300

catcattgag tatctagagg agatgcgtcc cactccgcga cttctgcctc aggacccaaa    360

gaagagggcc agcgtgcgta tgatttctga cctcatcgct ggtggcatcc agcccctgca    420

gaacctgtct gtcctgaagc aagtgggaga ggagatgcag ctgacctggg cccagaacgc    480

catcacttgt ggctttaacg ccctggagca gatcctacag agcacagcgg gcatatactg    540

tgtaggagac gaggtgacca tggctgatct gtgcttggtg cctcaggtgg caaatgctga    600

aagattcaag gtggatctca ccccctaccc taccatcagc tccatcaaca agaggctgct    660

ggtcttggag gccttccagg tgtctcaccc ctgccggcag ccagatacac ccactgagct    720

gagggcctag ctcccaaatc ctgccccgtt ggcacagggc cacaggagca gaagctgggt    780

gggctgaaga ggcctggaaa cgagagtctt aattgaggag atgggagact cgaactctag    840

ccctggatct gccttcctgc tgaaacttgt tccacctcag tcccctcatc tgtcacacgc    900

atgtggggtg gagtagggag atgcggggag cagggtgggc aggaatactg ttatctatgt    960

gacggggcag tcgtgaggct gagatgagaa tgcggattaa aatgcctggc gtgctcaccg   1020

taacaccacg gggaaggctg tgtgcctttt ctcatccgct tttgttgtgt gtgactccaa   1080

agaatgcccg cgctgaaatt tggcgtgaat taaactgaag cccaggcctc ta           1132


<210>  8515
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  8515

Met Lys Gln Val Pro Thr Leu Lys Ile Asp Gly Ile Thr Ile His Gln 
1               5                   10                  15


Ser Leu Ala Ile Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg 
            20                  25                  30


Leu Leu Pro Gln Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser 
        35                  40                  45


Asp Leu Ile Ala Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu 
    50                  55                  60


Lys Gln Val Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile 
65                  70                  75                  80


Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly 
                85                  90                  95


Ile Tyr Cys Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val 
            100                 105                 110


Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr 
        115                 120                 125


Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe 
    130                 135                 140


Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg 
145                 150                 155                 160


Ala 



<210>  8516
<211>  861
<212>  DNA
<213>  Homo sapiens

<400>  8516
tgattcgtcg agtctcactg agccttagtc gtcggcaggt cccaggcgcg aagtttctcg     60

gcctggagga gggggtcgcg cgaagtgcca gatgcaggcg gggaagctct ggccttgaaa    120

ggcatcgact acgagacggt gcccatcaat ctcataaagg atgggggcca acagttttct    180

aaggacttcc aggcactgaa tcctatgaag caggtgccaa ccctgaagat tgatggaatc    240

accattcacc agtcaaacct gtctgtcctg aagcaagtgg gagaggagat gcagctgacc    300

tgggcccaga acgccatcac ttgtggcttt aacgccctgg agcagatcct acagagcaca    360

gcgggcatat actgtgtagg agacgaggtg accatggctg atctgtgctt ggtgcctcag    420

gtggcaaatg ctgaaagatt caaggtggat ctcaccccct accctaccat cagctccatc    480

aacaagaggc tgctggtctt ggaggccttc caggtgtctc acccctgccg gcagccagat    540

acacccactg agctgagggc ctagctccca aatcctgccc cgttggcaca gggccacagg    600

agcagaagct gggtgggctg aagaggcctg gaaacgagag tcttaattga ggagatggga    660

gactcgaact ctagccctgg atctgccttc ctgctgaaac ttgttccacc tcagtcccct    720

catctgtcac acgcatgtgg ggtggagtag ggagatgcgg ggagcagggt gggcaggaat    780

actgttatct atgtgacggg gcagtcgtga ggctgagatg agaatgcgga ttaaaatgcc    840

tggcgtgctc accgtaacac c                                              861


<210>  8517
<211>  119
<212>  PRT
<213>  Homo sapiens

<400>  8517

Met Lys Gln Val Pro Thr Leu Lys Ile Asp Gly Ile Thr Ile His Gln 
1               5                   10                  15


Ser Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met Gln Leu Thr 
            20                  25                  30


Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile 
        35                  40                  45


Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu Val Thr Met 
    50                  55                  60


Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe Lys 
65                  70                  75                  80


Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu 
                85                  90                  95


Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro Asp 
            100                 105                 110


Thr Pro Thr Glu Leu Arg Ala 
        115


<210>  8518
<211>  966
<212>  DNA
<213>  Homo sapiens

<400>  8518
tgattcgtcg agtctcactg agccttagtc gtcggcaggt cccaggcgcg aagtttctcg     60

gcctggagga gggggtcgcg cgaagtgcca gatgcaggcg gggaagctct ggccttgaaa    120

ggcatcgact acgagacggt gcccatcaat ctcataaagg atgggggcca acagttttct    180

aaggacttcc aggcactgaa tcctatgaag caggtgccaa ccctgaagat tgatggaatc    240

accattcacc agtcaaacct gtctgtcctg aagcaagtgg gagaggagat gcagctgacc    300

tgggcccaga acgccatcac ttgtggcttt aacgccctgg agcagatcct acagagcaca    360

gcgggcatat actgtgtagg agacgaggtg accatggctg atctgtgctt ggtgcctcag    420

gtggcaaatg ctgaaagatt caaggtggat ctcaccccct accctaccat cagctccatc    480

aacaagaggc tgctggtctt ggaggccttc caggtgtctc acccctgccg gcagccagat    540

acacccactg agctgagggc ctagctccca aatcctgccc cgttggcaca gggccacagg    600

agcagaagct gggtgggctg aagaggcctg gaaacgagag tcttaattga ggagatggga    660

gactcgaact ctagccctgg atctgccttc ctgctgaaac ttgttccacc tcagtcccct    720

catctgtcac acgcatgtgg ggtggagtag ggagatgcgg ggagcagggt gggcaggaat    780

actgttatct atgtgacggg gcagtcgtga ggctgagatg agaatgcgga ttaaaatgcc    840

tggcgtgctc accgtaacac cacggggaag gctgtgtgcc ttttctcatc cgcttttgtt    900

gtgtgtgact ccaaagaatg cccgcgctga aatttggcgt gaattaaact gaagcccagg    960

cctcta                                                               966


<210>  8519
<211>  119
<212>  PRT
<213>  Homo sapiens

<400>  8519

Met Lys Gln Val Pro Thr Leu Lys Ile Asp Gly Ile Thr Ile His Gln 
1               5                   10                  15


Ser Asn Leu Ser Val Leu Lys Gln Val Gly Glu Glu Met Gln Leu Thr 
            20                  25                  30


Trp Ala Gln Asn Ala Ile Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile 
        35                  40                  45


Leu Gln Ser Thr Ala Gly Ile Tyr Cys Val Gly Asp Glu Val Thr Met 
    50                  55                  60


Ala Asp Leu Cys Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe Lys 
65                  70                  75                  80


Val Asp Leu Thr Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu 
                85                  90                  95


Leu Val Leu Glu Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro Asp 
            100                 105                 110


Thr Pro Thr Glu Leu Arg Ala 
        115


<210>  8520
<211>  551
<212>  DNA
<213>  Homo sapiens

<400>  8520
actgagcctt agtcgtcggc aggtcccagg cgcgaagttt ctcggcctgg aggagggggt     60

cgcgcgaagt gccagatgca ggcggggaag cccatcctct attcctattt ccgaagctcc    120

tgctcatgga gagttcgaat tgctctggcc ttgaaaggca tcgactacga gacggtgccc    180

atcaatctca taaaggatgg gggccaacag gtaagaaggc tgtgcccaga ccacaatgtg    240

ggaattggag gccttgaaca ggcaccaggc aggggaaaaa ggggaggctc tgccccagag    300

aagtgaacct gtgtcttgtg gactatcact gcaggaggct gctggctctc ccttgtggga    360

caaggtggca aggtgtgcag tagcaggagg cctgggaagg gcccaggtcc agactgtgta    420

ccctagcctg ggctctccag tgcctgaccc tgggagggtg ggtggctagt gggtccccac    480

cccatactgg gccctctgga tggctgacta gggtaggagc tgccttggtg gccacggtgt    540

gagatgcagg g                                                         551


<210>  8521
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  8521

Met Gln Ala Gly Lys Pro Ile Leu Tyr Ser Tyr Phe Arg Ser Ser Cys 
1               5                   10                  15


Ser Trp Arg Val Arg Ile Ala Leu Ala Leu Lys Gly Ile Asp Tyr Glu 
            20                  25                  30


Thr Val Pro Ile Asn Leu Ile Lys Asp Gly Gly Gln Gln Val Arg Arg 
        35                  40                  45


Leu Cys Pro Asp His Asn Val Gly Ile Gly Gly Leu Glu Gln Ala Pro 
    50                  55                  60


Gly Arg Gly Lys Arg Gly Gly Ser Ala Pro Glu Lys 
65                  70                  75


<210>  8522
<211>  1425
<212>  DNA
<213>  Homo sapiens

<400>  8522
ccgggagggt tgggccagag gaggcggtcc tggtagggag tgcgtagcag ggtggagtcg     60

ctgtccggtc gcgcttcact tctgctccgc cctccctgct ccccataaca gacccctccc    120

tccactaagg cttccaaacg tcgccccaag cctcccaatt tctcgcagcc cttcatgctc    180

ttctcttggc cctagcagga gtggtcacca gcagtccctg tcccttggca ccaggagtcc    240

ctgtagcctg gctaggtaag gaaagggagt tgcatctcca aataaggaag atccagttgt    300

ggccacccaa ttcctcctct tcgaaagaca ctttctgccc atcacctgct ttctgtgcca    360

ggaccatctt tactttctcc acaaaagccc atcctctatt cctatttccg aagctcctgc    420

tcatggagag ttcgaattgc tctggccttg aaaggcatcg actacgagac ggtgcccatc    480

aatctcataa aggatggggg ccaacagttt tctaaggact tccaggcact gaatcctatg    540

aagcaggtgc caaccctgaa gattgatgga atcaccattc accagtcact ggccatcatt    600

gagtatctag aggagatgcg tcccactccg cgacttctgc ctcaggaccc aaagaagagg    660

gccagcgtgc gtatgatttc tgacctcatc gctggtggca tccagcccct gcagaacctg    720

tctgtcctga agcaagtggg agaggagatg cagctgacct gggcccagaa cgccatcact    780

tgtggcttta acgccctgga gcagatccta cagagcacag cgggcatata ctgtgtagga    840

gacgaggtga ccatggctga tctgtgcttg gtgcctcagg tggcaaatgc tgaaagattc    900

aaggtggatc tcacccccta ccctaccatc agctccatca acaagaggct gctggtcttg    960

gaggccttcc aggtgtctca cccctgccgg cagccagata cacccactga gctgagggcc   1020

tagctcccaa atcctgcccc gttggcacag ggccacagga gcagaagctg ggtgggctga   1080

agaggcctgg aaacgagagt cttaattgag gagatgggag actcgaactc tagccctgga   1140

tctgccttcc tgctgaaact tgttccacct cagtcccctc atctgtcaca cgcatgtggg   1200

gtggagtagg gagatgcggg gagcagggtg ggcaggaata ctgttatcta tgtgacgggg   1260

cagtcgtgag gctgagatga gaatgcggat taaaatgcct ggcgtgctca ccgtaacacc   1320

acggggaagg ctgtgtgcct tttctcatcc gcttttgttg tgtgtgactc caaagaatgc   1380

ccgcgctgaa atttggcgtg aattaaactg aagcccaggc ctcta                   1425


<210>  8523
<211>  161
<212>  PRT
<213>  Homo sapiens

<400>  8523

Met Lys Gln Val Pro Thr Leu Lys Ile Asp Gly Ile Thr Ile His Gln 
1               5                   10                  15


Ser Leu Ala Ile Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg 
            20                  25                  30


Leu Leu Pro Gln Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser 
        35                  40                  45


Asp Leu Ile Ala Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu 
    50                  55                  60


Lys Gln Val Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile 
65                  70                  75                  80


Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly 
                85                  90                  95


Ile Tyr Cys Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val 
            100                 105                 110


Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr 
        115                 120                 125


Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe 
    130                 135                 140


Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg 
145                 150                 155                 160


Ala 



<210>  8524
<211>  5536
<212>  DNA
<213>  Homo sapiens

<400>  8524
tctagtggtc accagcagtc cctgtccctt ggcaccagga gtccctgtag cctggctagg     60

taaggaaagg gagttgcatc tccaaataag gaagatccag ttgtggccac ccaattcctc    120

ctcttcgaaa gacactttct gcccatcacc tgctttctgt gccaggacca tctttacttt    180

ctccacaaaa ggtaccttca ggacaggctg ggactgctgg gcttgggaac catcttggaa    240

gggcctaggt tcccacttac acccttgcca tctagcagac tgagttggta gtacagggat    300

ggcaatagca agttcagaga gcagcttaat atgctagggg tggcagaggg gagagggagc    360

tttggtgaaa tgtctatagt cagaggggta gtaaacaggg catctgagaa gttctttcaa    420

gttctcccct atccataggg atacacatgt tttggtggga agattcatga gtgctaatca    480

ctggcgagtc tttcctgggt tccactttga aatgctggct cccgaagaag taccagagaa    540

attaactttg agccccttaa accttggagt agagatcgca cacccagctg cccccaaggg    600

cccaaaggta acaaaaatga gaaaagtggg ccagatatgg gccatggcag acctgagagc    660

gcatacgctg gttgatgggg gccattagtc tgttcccatc aattgctgct atttaggaac    720

ccaaatctgt ctccagattt ttttaaagaa aaaaaacaaa caggtgttgt atataaaata    780

tcatgatttt tatttttatt ttattttatt atttatttat tttgagatgg agtcttgctc    840

tgtcccccag gctggagggc agtgacacga tcttggctca ctgtatcctc cgcctcctgg    900

gttcaagcaa ttctcatacc tcagcctccc aagtaggtgt gattacagat gcacaccacc    960

acacctggct aatttttgtt tagccatgtt gtttcgccat gttggccagg ctggtctcga   1020

actcctgacc tcaggtgatc tgctggcctc agcctcccaa agtgctggga ttacaggcat   1080

gacccaccat actagaatga aatgtcctga tttttaaaca ttggcaacta cttgaaacat   1140

tttaaactac tgtgttgagc aaacagaaat tctgagggcc agatagggcc ccagtgagct   1200

gccagctttt gacctcacct ttggggtgag tgagcatatc tgccagctgt ttttatgggg   1260

acagccgaga gcccggagga ctgctgggag gtggggttga aggagatatg taccaaagcg   1320

tcaaaaaatt agaattcctt gtcttgctgc attgctagag gatgccctgc catcatttta   1380

gggcaacctt tgttttacaa atgagggagc cgaagattta aaaaggcaga ggtttgtcca   1440

aggtcatgca gagctggttc ctgcaccagg tccagactcc agatgccagc tcccagcccg   1500

ctccaccact caaaatactg catcaaaacc aggccacgct ctgttggggg gacaccaaac   1560

ctggccccag caggagcgta agaaacttcc tgcgagttgg aaaaaaatgc cttttttttt   1620

tttttttttt tgagacgcag tctcgctctg gagtgcagtg gtgcgatctc ggcccactgt   1680

gacctccacc tctcaggttc aagctattct cttacctcaa cctcctgagt agctgagatt   1740

acaggcaccc actaccacac ctggctgatt tttttttgta ttttcagtag agacagggtt   1800

tcaccatgtt ggccaggctg gtctcaaact cctcacctca aatgatccac ccaccttggc   1860

tcccgaagtg ctgggattac aggcgtgagc cactgtgcct ggccagaaat gccctttctg   1920

accagagtca aagttccccc aatgcctggg tagcccagct tccccattgg ctcctgaaat   1980

ccaccccttt aggtttcctt tccctgctca gaagctgtgc cagaggggac atttcctggg   2040

aggctgaggg tcaccacgat accatgacag agtctggcaa ggtatggaag gcactctcag   2100

gctagctgcc cctttggggg cctcttggac ctcaggagct caaaccagca taattttgga   2160

gccaagggac ctcatgagcc tctcagagag cttggagtct gccctgattt gcacagatgc   2220

aggcctgaga gaggaggcct ggcaggacag gaagaaatgg ttgactcctc ccaagctgga   2280

gcccacccag catgggttaa cacgcgcctt catcctctct ctcctcagcc catcctctat   2340

tcctatttcc gaagctcctg ctcatggaga gttcgaattg gtaagagatg tgcctcctcc   2400

aggatgagtg ctggagtggg gtggactggg gcggataagc ccgggtgcaa agctggcctg   2460

ggatggaagg gttgctctgt cagagaggac ctcaccccca gcaaccagca tcccccggct   2520

cctagaaccc ccatccctgc atggcatctc caccccggaa acacagggtg agggtgggag   2580

gaagggggtt gttttttccc ttgggactga cacttctccc aacactgctc tccaaagccc   2640

cttggcaacc atgtttaaag cagggtcaca aaatccacat gcccctggta actggcaggg   2700

gaacagctgg cccttctcag ttcttatttt atttgaactg gcaaagcaaa cagaacgggc   2760

cagcatcagc ctcggaggct tcagaaaagc agaaacaagg gccctgtggc tagtccttgt   2820

ttgacccttc cctcccttgg cttaacacag cctttggcaa aggtcataac caaagcagcc   2880

tgtactgagg aaaagctctg tgctgagtgc ttttgtgtgc ctgattccat ttaaacctca   2940

gcaaccctag gagggaggta ctattattac tgtccccatt gtatagagga ggaagctgag   3000

gcacaaaaaa caggcaacat tcagtaactt gcccaagatc tttcagttac taagaggcag   3060

aactggaatt tgaaccaggt agtctggctc cagaggccca ttaagttact tgcccagggc   3120

cacacagtta gcaaatgact gtgatgaaat ttgaacccaa gaagcttgcc tccagagtgt   3180

ggaggcaaag ccatcctccg tgacccctcc tccatcccat agtcacttgg tatttgctgg   3240

gatcagtaag caagagcact gggtgccagg agaaactttc ctccaagaag atgaacccat   3300

ccctgggcgc cagtacctct gccctggctg agccagaagc cggagcaata taggtgctgt   3360

ctgtacggcc tgtgtgcttt ggccttccct cctccaggtg tctcctccag ccccaaacac   3420

tgtcactccc cagactggag ctgaccaaca ctaggaggag cctggtattg cccaggctct   3480

ccacaccatg acatgtctgg tcctcctccc ctcattcctt tgcccttccc tgagattggc   3540

catcaccata cttgaatgcc caagtgtgtg taatacacac atgcatgcac acgcacgcag   3600

tcttctccac tagtgttgac ccacccaagt tttttttacc ctcagcttgc caggggaaat   3660

tatcaaaagg gatggagagg aaatctggtg actggagtca cggcaaatgc tctgaggcca   3720

ccaaagagcc tgatgcctgt ctagaatctc tagtaaacag ccctgagaac agagagaata   3780

gattggaaga gattcttctc caacagaaca agagtgccat ctgtctgtgt gtgctgtgtg   3840

tggccacctg agctccttcc cttggccctt agttgccttc ttgagggagt aattgcatgt   3900

cttcaaccaa gacactggtc accactgttt aaggccctgg gggggcagag ttaaacacaa   3960

cacagccttg ctgaactcca ggagcccaca gagtgccagg gcatacacct ttatcaccat   4020

ccagggggca tgagggcccc attggggggg tccagatctt gaggtctcta agagttcagg   4080

ggtgagtgag gcagagcatc gtgcatctgg ggtagggagc acgtggtgac aaggaaagct   4140

gagagaaggg gatagtgcca cggtgagcct tgaccaccca gaagtgttag agaagcctcc   4200

ccctctttgg ccttaatgtc accttagaag ggctctttcc tttaagagta cggcgagagg   4260

ctgttctttg actccgctat gtgcggtctc tcctagctct ggccttgaaa ggcatcgact   4320

acgagacggt gcccatcaat ctcataaagg atgggggcca acagttttct aaggacttcc   4380

aggcactgaa tcctatgaag caggtgccaa ccctgaagat tgatggaatc accattcacc   4440

agtcagtgag tgcagggcct gggggagggc cctcatgaga gcagtgccct gaatgagagc   4500

gcctgacatc tcttcctcgc ctgtgtacag tcaaggtgcc tagcacatag gagaggctca   4560

atacaagact cgtggggagg gtgcgaggtt atttaggaaa ataagggaag attcaagcac   4620

atggagaacc aagttctgca tgataaggtc caaaaaggct tatagggctt gagctgagca   4680

gaagcagggg ggaagaggtg tagtgatggt gctggaagag gagaaggagg agtttgctgg   4740

ccctgtcccc tctggtccag gggtcctggg ccctctccct gcctcactgc tcccctctgg   4800

acagctggcc atcattgagt atctagagga gatgcgtccc actccgcgac ttctgcctca   4860

ggacccaaag aagagggcca gcgtgcgtat gatttctgac ctcatcgctg gtggcatcca   4920

gcccctgcag aacctgtctg tcctgaagca agtgggagag gagatgcagc tgacctgggc   4980

ccagaacgcc atcacttgtg gctttaacgc cctggagcag atcctacaga gcacagcggg   5040

catatactgt gtaggagacg aggtgaccat ggctgatctg tgcttggtgc ctcaggtggc   5100

aaatgctgaa agattcaagg tggatctcac cccctaccct accatcagct ccatcaacaa   5160

gaggctgctg gtcttggagg ccttccaggt gtctcacccc tgccggcagc cagatacacc   5220

cactgagctg agggcctagc tcccaaatcc tgccccgttg gcacagggcc acaggagcag   5280

aagctgggtg ggctgaagag gcctggaaac gagagtctta attgaggaga tgggagactc   5340

gaactctagc cctggatctg ccttcctgct gaaacttgtt ccacctcagt cccctcatct   5400

gtcacacgca tgtggggtgg agtagggaga tgcggggagc agggtgggca ggaatactgt   5460

tatctatgtg acggggcagt cgtgaggctg agatgagaat gcggattaaa atgcctggcg   5520

tgctcaccgt aacacc                                                   5536


<210>  8525
<211>  177
<212>  PRT
<213>  Homo sapiens

<400>  8525

Met Val Leu Glu Glu Glu Lys Glu Glu Phe Ala Gly Pro Val Pro Ser 
1               5                   10                  15


Gly Pro Gly Val Leu Gly Pro Leu Pro Ala Ser Leu Leu Pro Ser Gly 
            20                  25                  30


Gln Leu Ala Ile Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg 
        35                  40                  45


Leu Leu Pro Gln Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser 
    50                  55                  60


Asp Leu Ile Ala Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu 
65                  70                  75                  80


Lys Gln Val Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile 
                85                  90                  95


Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly 
            100                 105                 110


Ile Tyr Cys Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val 
        115                 120                 125


Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr 
    130                 135                 140


Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe 
145                 150                 155                 160


Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg 
                165                 170                 175


Ala 



<210>  8526
<211>  5641
<212>  DNA
<213>  Homo sapiens

<400>  8526
tctagtggtc accagcagtc cctgtccctt ggcaccagga gtccctgtag cctggctagg     60

taaggaaagg gagttgcatc tccaaataag gaagatccag ttgtggccac ccaattcctc    120

ctcttcgaaa gacactttct gcccatcacc tgctttctgt gccaggacca tctttacttt    180

ctccacaaaa ggtaccttca ggacaggctg ggactgctgg gcttgggaac catcttggaa    240

gggcctaggt tcccacttac acccttgcca tctagcagac tgagttggta gtacagggat    300

ggcaatagca agttcagaga gcagcttaat atgctagggg tggcagaggg gagagggagc    360

tttggtgaaa tgtctatagt cagaggggta gtaaacaggg catctgagaa gttctttcaa    420

gttctcccct atccataggg atacacatgt tttggtggga agattcatga gtgctaatca    480

ctggcgagtc tttcctgggt tccactttga aatgctggct cccgaagaag taccagagaa    540

attaactttg agccccttaa accttggagt agagatcgca cacccagctg cccccaaggg    600

cccaaaggta acaaaaatga gaaaagtggg ccagatatgg gccatggcag acctgagagc    660

gcatacgctg gttgatgggg gccattagtc tgttcccatc aattgctgct atttaggaac    720

ccaaatctgt ctccagattt ttttaaagaa aaaaaacaaa caggtgttgt atataaaata    780

tcatgatttt tatttttatt ttattttatt atttatttat tttgagatgg agtcttgctc    840

tgtcccccag gctggagggc agtgacacga tcttggctca ctgtatcctc cgcctcctgg    900

gttcaagcaa ttctcatacc tcagcctccc aagtaggtgt gattacagat gcacaccacc    960

acacctggct aatttttgtt tagccatgtt gtttcgccat gttggccagg ctggtctcga   1020

actcctgacc tcaggtgatc tgctggcctc agcctcccaa agtgctggga ttacaggcat   1080

gacccaccat actagaatga aatgtcctga tttttaaaca ttggcaacta cttgaaacat   1140

tttaaactac tgtgttgagc aaacagaaat tctgagggcc agatagggcc ccagtgagct   1200

gccagctttt gacctcacct ttggggtgag tgagcatatc tgccagctgt ttttatgggg   1260

acagccgaga gcccggagga ctgctgggag gtggggttga aggagatatg taccaaagcg   1320

tcaaaaaatt agaattcctt gtcttgctgc attgctagag gatgccctgc catcatttta   1380

gggcaacctt tgttttacaa atgagggagc cgaagattta aaaaggcaga ggtttgtcca   1440

aggtcatgca gagctggttc ctgcaccagg tccagactcc agatgccagc tcccagcccg   1500

ctccaccact caaaatactg catcaaaacc aggccacgct ctgttggggg gacaccaaac   1560

ctggccccag caggagcgta agaaacttcc tgcgagttgg aaaaaaatgc cttttttttt   1620

tttttttttt tgagacgcag tctcgctctg gagtgcagtg gtgcgatctc ggcccactgt   1680

gacctccacc tctcaggttc aagctattct cttacctcaa cctcctgagt agctgagatt   1740

acaggcaccc actaccacac ctggctgatt tttttttgta ttttcagtag agacagggtt   1800

tcaccatgtt ggccaggctg gtctcaaact cctcacctca aatgatccac ccaccttggc   1860

tcccgaagtg ctgggattac aggcgtgagc cactgtgcct ggccagaaat gccctttctg   1920

accagagtca aagttccccc aatgcctggg tagcccagct tccccattgg ctcctgaaat   1980

ccaccccttt aggtttcctt tccctgctca gaagctgtgc cagaggggac atttcctggg   2040

aggctgaggg tcaccacgat accatgacag agtctggcaa ggtatggaag gcactctcag   2100

gctagctgcc cctttggggg cctcttggac ctcaggagct caaaccagca taattttgga   2160

gccaagggac ctcatgagcc tctcagagag cttggagtct gccctgattt gcacagatgc   2220

aggcctgaga gaggaggcct ggcaggacag gaagaaatgg ttgactcctc ccaagctgga   2280

gcccacccag catgggttaa cacgcgcctt catcctctct ctcctcagcc catcctctat   2340

tcctatttcc gaagctcctg ctcatggaga gttcgaattg gtaagagatg tgcctcctcc   2400

aggatgagtg ctggagtggg gtggactggg gcggataagc ccgggtgcaa agctggcctg   2460

ggatggaagg gttgctctgt cagagaggac ctcaccccca gcaaccagca tcccccggct   2520

cctagaaccc ccatccctgc atggcatctc caccccggaa acacagggtg agggtgggag   2580

gaagggggtt gttttttccc ttgggactga cacttctccc aacactgctc tccaaagccc   2640

cttggcaacc atgtttaaag cagggtcaca aaatccacat gcccctggta actggcaggg   2700

gaacagctgg cccttctcag ttcttatttt atttgaactg gcaaagcaaa cagaacgggc   2760

cagcatcagc ctcggaggct tcagaaaagc agaaacaagg gccctgtggc tagtccttgt   2820

ttgacccttc cctcccttgg cttaacacag cctttggcaa aggtcataac caaagcagcc   2880

tgtactgagg aaaagctctg tgctgagtgc ttttgtgtgc ctgattccat ttaaacctca   2940

gcaaccctag gagggaggta ctattattac tgtccccatt gtatagagga ggaagctgag   3000

gcacaaaaaa caggcaacat tcagtaactt gcccaagatc tttcagttac taagaggcag   3060

aactggaatt tgaaccaggt agtctggctc cagaggccca ttaagttact tgcccagggc   3120

cacacagtta gcaaatgact gtgatgaaat ttgaacccaa gaagcttgcc tccagagtgt   3180

ggaggcaaag ccatcctccg tgacccctcc tccatcccat agtcacttgg tatttgctgg   3240

gatcagtaag caagagcact gggtgccagg agaaactttc ctccaagaag atgaacccat   3300

ccctgggcgc cagtacctct gccctggctg agccagaagc cggagcaata taggtgctgt   3360

ctgtacggcc tgtgtgcttt ggccttccct cctccaggtg tctcctccag ccccaaacac   3420

tgtcactccc cagactggag ctgaccaaca ctaggaggag cctggtattg cccaggctct   3480

ccacaccatg acatgtctgg tcctcctccc ctcattcctt tgcccttccc tgagattggc   3540

catcaccata cttgaatgcc caagtgtgtg taatacacac atgcatgcac acgcacgcag   3600

tcttctccac tagtgttgac ccacccaagt tttttttacc ctcagcttgc caggggaaat   3660

tatcaaaagg gatggagagg aaatctggtg actggagtca cggcaaatgc tctgaggcca   3720

ccaaagagcc tgatgcctgt ctagaatctc tagtaaacag ccctgagaac agagagaata   3780

gattggaaga gattcttctc caacagaaca agagtgccat ctgtctgtgt gtgctgtgtg   3840

tggccacctg agctccttcc cttggccctt agttgccttc ttgagggagt aattgcatgt   3900

cttcaaccaa gacactggtc accactgttt aaggccctgg gggggcagag ttaaacacaa   3960

cacagccttg ctgaactcca ggagcccaca gagtgccagg gcatacacct ttatcaccat   4020

ccagggggca tgagggcccc attggggggg tccagatctt gaggtctcta agagttcagg   4080

ggtgagtgag gcagagcatc gtgcatctgg ggtagggagc acgtggtgac aaggaaagct   4140

gagagaaggg gatagtgcca cggtgagcct tgaccaccca gaagtgttag agaagcctcc   4200

ccctctttgg ccttaatgtc accttagaag ggctctttcc tttaagagta cggcgagagg   4260

ctgttctttg actccgctat gtgcggtctc tcctagctct ggccttgaaa ggcatcgact   4320

acgagacggt gcccatcaat ctcataaagg atgggggcca acagttttct aaggacttcc   4380

aggcactgaa tcctatgaag caggtgccaa ccctgaagat tgatggaatc accattcacc   4440

agtcagtgag tgcagggcct gggggagggc cctcatgaga gcagtgccct gaatgagagc   4500

gcctgacatc tcttcctcgc ctgtgtacag tcaaggtgcc tagcacatag gagaggctca   4560

atacaagact cgtggggagg gtgcgaggtt atttaggaaa ataagggaag attcaagcac   4620

atggagaacc aagttctgca tgataaggtc caaaaaggct tatagggctt gagctgagca   4680

gaagcagggg ggaagaggtg tagtgatggt gctggaagag gagaaggagg agtttgctgg   4740

ccctgtcccc tctggtccag gggtcctggg ccctctccct gcctcactgc tcccctctgg   4800

acagctggcc atcattgagt atctagagga gatgcgtccc actccgcgac ttctgcctca   4860

ggacccaaag aagagggcca gcgtgcgtat gatttctgac ctcatcgctg gtggcatcca   4920

gcccctgcag aacctgtctg tcctgaagca agtgggagag gagatgcagc tgacctgggc   4980

ccagaacgcc atcacttgtg gctttaacgc cctggagcag atcctacaga gcacagcggg   5040

catatactgt gtaggagacg aggtgaccat ggctgatctg tgcttggtgc ctcaggtggc   5100

aaatgctgaa agattcaagg tggatctcac cccctaccct accatcagct ccatcaacaa   5160

gaggctgctg gtcttggagg ccttccaggt gtctcacccc tgccggcagc cagatacacc   5220

cactgagctg agggcctagc tcccaaatcc tgccccgttg gcacagggcc acaggagcag   5280

aagctgggtg ggctgaagag gcctggaaac gagagtctta attgaggaga tgggagactc   5340

gaactctagc cctggatctg ccttcctgct gaaacttgtt ccacctcagt cccctcatct   5400

gtcacacgca tgtggggtgg agtagggaga tgcggggagc agggtgggca ggaatactgt   5460

tatctatgtg acggggcagt cgtgaggctg agatgagaat gcggattaaa atgcctggcg   5520

tgctcaccgt aacaccacgg ggaaggctgt gtgccttttc tcatccgctt ttgttgtgtg   5580

tgactccaaa gaatgcccgc gctgaaattt ggcgtgaatt aaactgaagc ccaggcctct   5640

a                                                                   5641


<210>  8527
<211>  177
<212>  PRT
<213>  Homo sapiens

<400>  8527

Met Val Leu Glu Glu Glu Lys Glu Glu Phe Ala Gly Pro Val Pro Ser 
1               5                   10                  15


Gly Pro Gly Val Leu Gly Pro Leu Pro Ala Ser Leu Leu Pro Ser Gly 
            20                  25                  30


Gln Leu Ala Ile Ile Glu Tyr Leu Glu Glu Met Arg Pro Thr Pro Arg 
        35                  40                  45


Leu Leu Pro Gln Asp Pro Lys Lys Arg Ala Ser Val Arg Met Ile Ser 
    50                  55                  60


Asp Leu Ile Ala Gly Gly Ile Gln Pro Leu Gln Asn Leu Ser Val Leu 
65                  70                  75                  80


Lys Gln Val Gly Glu Glu Met Gln Leu Thr Trp Ala Gln Asn Ala Ile 
                85                  90                  95


Thr Cys Gly Phe Asn Ala Leu Glu Gln Ile Leu Gln Ser Thr Ala Gly 
            100                 105                 110


Ile Tyr Cys Val Gly Asp Glu Val Thr Met Ala Asp Leu Cys Leu Val 
        115                 120                 125


Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr Pro Tyr 
    130                 135                 140


Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu Ala Phe 
145                 150                 155                 160


Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu Leu Arg 
                165                 170                 175


Ala 



<210>  8528
<211>  2344
<212>  DNA
<213>  Homo sapiens

<400>  8528
acaactaagt attaaaaaca gttcatctgt gccagcttct actctgaatg aggaaatagc     60

cccagaaagg tggagtgact taggagtccc acaggtaggt cataacaaag tggggactaa    120

gtcagaatcc ctgcatgcct atgccctcta cccgcatgtc gctttaacaa aggatgttgg    180

agcagacaga catctccatt ttataatgag gaaacagagg gaaaatggct ccaggggtgc    240

caagatggag ccaggctgga aatctctgga agccggtctt gtggacctcc ctcatcccag    300

ccccaccctc tttcacactc cctctcctca caagggacca tgcaagggag aagtgaggga    360

gacaggcctc gagttgtggg cacacctgcc acagccatgg ccgcgtcctg tgtcacatga    420

atagggattc ttgcacatct ctgacagaat cacgtggctt tttgaggcca ctggggcagc    480

ctgcaaaggt ggctgctggg atggctacct ccctccaacc tcagggccct tggttgaagg    540

aaggggctca tggagcctgg gggagaaggg atagacatcc agccaggggc agatgggaag    600

tgaacttccc tgagggggtt tggcgaaggg gtagccccca cccagctgtc agcgcaatca    660

cagattttct ttgggctgca cagaacctgt ctgtcctgaa gcaagtggga gaggagatgc    720

agctgacctg ggcccagaac gccatcactt gtggctttaa cggtgagtcc tcacctctgt    780

gagctgcccc acagtggcct cttagaggta tggccctcgc acacaggggc ctgggtatct    840

gaaccagcct cccaggctgc tttgggcctg acagttgcat ggatgagggc aggactgggg    900

aggcaatggg ctgggtgggc atccagacct tagctccagc acttctggga acctcggtcc    960

ctgagcccac agcccttcat agctggatgg cccaacttca gcttcactgc ctactccagc   1020

tgggaaacca aggccagcac agcgccagcc atcagagtga gagctgtcac cgtggccagt   1080

ggcagggctt gtccactcga gtggggaaat ggtgattgtc tgtgcggagc ctcaggaaac   1140

agcagctcat ccctaacagc tctctcgaga cctggctgcc acattctcac cagcagccat   1200

gcccagtctg tcactcagtt gggcgcccat ttcataacta tggaggccaa ggcccagaaa   1260

gctttgtgtc ccctccctgc gcccagaata agatgtttat gtggcctccc cacagccctg   1320

gagcagatcc tacagagcac agcgggcata tactgtgtag gagacgaggt aagctgtccc   1380

cagacctccc caggcccagc cacagtggct gcctccctca tgctgacctc cctcaagctc   1440

agagcttcct gagaaggcgt ctgcaggggg atctctgtgc catggggcac tcctcagctc   1500

actcccacta aaccgtctta agagggagtt actcaaggta gaagactggc tgtgagagga   1560

tgaggcgggc cagcatcagt tgagggattg tgctagatga tgtctgcgca gtcaaggcaa   1620

tccatcttct ctggccctct caacccacag agttggttgt cagggcaact ggagcatggc   1680

ctgggagggc acttcagctc cgggggacag actcatgcag gcctagggca gacaagaatt   1740

ggaggtggga tgggtgaaag agccgaagca gattgttggt acccccagta gagtcgcagt   1800

ggacacaccc agtccagcca ctgactctgg ggtatgcacc ctgatgggaa cccaccggga   1860

cctctttcag gtgaccatgg ctgatctgtg cttggtgcct caggtggcaa atgctgaaag   1920

attcaaggtg gatctcaccc cctaccctac catcagctcc atcaacaaga ggctgctggt   1980

cttggaggcc ttccaggtgt ctcacccctg ccggcagcca gatacaccca ctgagctgag   2040

ggcctagctc ccaaatcctg ccccgttggc acagggccac aggagcagaa gctgggtggg   2100

ctgaagaggc ctggaaacga gagtcttaat tgaggagatg ggagactcga actctagccc   2160

tggatctgcc ttcctgctga aacttgttcc acctcagtcc cctcatctgt cacacgcatg   2220

tggggtggag tagggagatg cggggagcag ggtgggcagg aatactgtta tctatgtgac   2280

ggggcagtcg tgaggctgag atgagaatgc ggattaaaat gcctggcgtg ctcaccgtaa   2340

cacc                                                                2344


<210>  8529
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  8529

Met Gly Thr His Arg Asp Leu Phe Gln Val Thr Met Ala Asp Leu Cys 
1               5                   10                  15


Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr 
            20                  25                  30


Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu 
        35                  40                  45


Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu 
    50                  55                  60


Leu Arg Ala 
65


<210>  8530
<211>  2449
<212>  DNA
<213>  Homo sapiens

<400>  8530
acaactaagt attaaaaaca gttcatctgt gccagcttct actctgaatg aggaaatagc     60

cccagaaagg tggagtgact taggagtccc acaggtaggt cataacaaag tggggactaa    120

gtcagaatcc ctgcatgcct atgccctcta cccgcatgtc gctttaacaa aggatgttgg    180

agcagacaga catctccatt ttataatgag gaaacagagg gaaaatggct ccaggggtgc    240

caagatggag ccaggctgga aatctctgga agccggtctt gtggacctcc ctcatcccag    300

ccccaccctc tttcacactc cctctcctca caagggacca tgcaagggag aagtgaggga    360

gacaggcctc gagttgtggg cacacctgcc acagccatgg ccgcgtcctg tgtcacatga    420

atagggattc ttgcacatct ctgacagaat cacgtggctt tttgaggcca ctggggcagc    480

ctgcaaaggt ggctgctggg atggctacct ccctccaacc tcagggccct tggttgaagg    540

aaggggctca tggagcctgg gggagaaggg atagacatcc agccaggggc agatgggaag    600

tgaacttccc tgagggggtt tggcgaaggg gtagccccca cccagctgtc agcgcaatca    660

cagattttct ttgggctgca cagaacctgt ctgtcctgaa gcaagtggga gaggagatgc    720

agctgacctg ggcccagaac gccatcactt gtggctttaa cggtgagtcc tcacctctgt    780

gagctgcccc acagtggcct cttagaggta tggccctcgc acacaggggc ctgggtatct    840

gaaccagcct cccaggctgc tttgggcctg acagttgcat ggatgagggc aggactgggg    900

aggcaatggg ctgggtgggc atccagacct tagctccagc acttctggga acctcggtcc    960

ctgagcccac agcccttcat agctggatgg cccaacttca gcttcactgc ctactccagc   1020

tgggaaacca aggccagcac agcgccagcc atcagagtga gagctgtcac cgtggccagt   1080

ggcagggctt gtccactcga gtggggaaat ggtgattgtc tgtgcggagc ctcaggaaac   1140

agcagctcat ccctaacagc tctctcgaga cctggctgcc acattctcac cagcagccat   1200

gcccagtctg tcactcagtt gggcgcccat ttcataacta tggaggccaa ggcccagaaa   1260

gctttgtgtc ccctccctgc gcccagaata agatgtttat gtggcctccc cacagccctg   1320

gagcagatcc tacagagcac agcgggcata tactgtgtag gagacgaggt aagctgtccc   1380

cagacctccc caggcccagc cacagtggct gcctccctca tgctgacctc cctcaagctc   1440

agagcttcct gagaaggcgt ctgcaggggg atctctgtgc catggggcac tcctcagctc   1500

actcccacta aaccgtctta agagggagtt actcaaggta gaagactggc tgtgagagga   1560

tgaggcgggc cagcatcagt tgagggattg tgctagatga tgtctgcgca gtcaaggcaa   1620

tccatcttct ctggccctct caacccacag agttggttgt cagggcaact ggagcatggc   1680

ctgggagggc acttcagctc cgggggacag actcatgcag gcctagggca gacaagaatt   1740

ggaggtggga tgggtgaaag agccgaagca gattgttggt acccccagta gagtcgcagt   1800

ggacacaccc agtccagcca ctgactctgg ggtatgcacc ctgatgggaa cccaccggga   1860

cctctttcag gtgaccatgg ctgatctgtg cttggtgcct caggtggcaa atgctgaaag   1920

attcaaggtg gatctcaccc cctaccctac catcagctcc atcaacaaga ggctgctggt   1980

cttggaggcc ttccaggtgt ctcacccctg ccggcagcca gatacaccca ctgagctgag   2040

ggcctagctc ccaaatcctg ccccgttggc acagggccac aggagcagaa gctgggtggg   2100

ctgaagaggc ctggaaacga gagtcttaat tgaggagatg ggagactcga actctagccc   2160

tggatctgcc ttcctgctga aacttgttcc acctcagtcc cctcatctgt cacacgcatg   2220

tggggtggag tagggagatg cggggagcag ggtgggcagg aatactgtta tctatgtgac   2280

ggggcagtcg tgaggctgag atgagaatgc ggattaaaat gcctggcgtg ctcaccgtaa   2340

caccacgggg aaggctgtgt gccttttctc atccgctttt gttgtgtgtg actccaaaga   2400

atgcccgcgc tgaaatttgg cgtgaattaa actgaagccc aggcctcta               2449


<210>  8531
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  8531

Met Gly Thr His Arg Asp Leu Phe Gln Val Thr Met Ala Asp Leu Cys 
1               5                   10                  15


Leu Val Pro Gln Val Ala Asn Ala Glu Arg Phe Lys Val Asp Leu Thr 
            20                  25                  30


Pro Tyr Pro Thr Ile Ser Ser Ile Asn Lys Arg Leu Leu Val Leu Glu 
        35                  40                  45


Ala Phe Gln Val Ser His Pro Cys Arg Gln Pro Asp Thr Pro Thr Glu 
    50                  55                  60


Leu Arg Ala 
65


<210>  8532
<211>  3099
<212>  DNA
<213>  Homo sapiens

<400>  8532
gcttctctag ggagtgtcag gcgcacacag ggttaagtta gttccctccc tggtaggagg     60

gagaggagga ggaggggaaa agcagcatac tgtctcaggc tgggtacctt gtagttagtt    120

gtacgttcga aacctgtcgc cgtcacttgc gcgtttggca ttatccattg tcaccgcgga    180

ggaacgagcg ctcgagatat catcagtgcc cgcaaatctc cgcgccaagg cgctgagcta    240

ctcctttccg aggtgcgcct ctggtcctcc gtccctggtg cccagcagcg gcgaggcggc    300

atctccgctc ccgccgccgt gtccaccgag ccctgggatc agggtggcag ttctcaacga    360

tgggcaggag ggacctcggc ggcgacccct aaaacaatac catgccccgg gatccccgct    420

gctgccgcgc cagcgtcttc cctttccacc tccctgaccc tgtcggattc ggatgagccc    480

attgcaagga gaagacgcag ccgtcagatt gcagattgag cttaaccaag aagttcgtag    540

gctaatcaag gctggcttga cctacaaaag aagaagagag ttctgcctgc ccacttgggc    600

ttgtgttgac acggctgata acttgccatc acctgttgcc agtgtggaaa aattctccct    660

gttgaatttt ttgcacatgg aggacagcag caaagagggc aacacaggct gataagacca    720

gagacagcag ggagattatt ttaccatacg ccctcaggac gttccctcta gctggagttc    780

tggacttcaa cagaacccca tccagtcatt ttgattttgc tgtttatttt ttttttcttt    840

ttctttttcc caccacattg tattttattt ccgtacttca gaaatgggcc tacagaccac    900

aaagtggccc agccatgggg cttttttcct gaagtcttgg cttatcattt ccctggggct    960

ctactcacag gtgtccaaac tcctggcctg ccctagtgtg tgccgctgcg acaggaactt   1020

tgtctactgt aatgagcgaa gcttgacctc agtgcctctt gggatcccgg agggcgtaac   1080

tgtactctac ctccacaaca accaaattaa taatgctgga tttcctgcag aactgcacaa   1140

tgtacagtcg gtgcacacgg tctacctgta tggcaaccaa ctggacgaat tccccatgaa   1200

ccttcccaag aatgtcagag ttctccattt gcaggaaaac aatattcaga ccatttcacg   1260

ggctgctctt gcccagctct tgaagcttga agagctgcac ctggatgaca actccatatc   1320

cacagtgggg gtggaagacg gggccttccg ggaggctatt agcctcaaat tgttgttttt   1380

gtctaagaat cacctgagca gtgtgcctgt tgggcttcct gtggacttgc aagagctgag   1440

agtggatgaa aatcgaattg ctgtcatatc cgacatggcc ttccagaatc tcacgagctt   1500

ggagcgtctt attgtggacg ggaacctcct gaccaacaag ggtatcgccg agggcacctt   1560

cagccatctc accaagctca aggaattttc aattgtacgt aattcgctgt cccaccctcc   1620

tcccgatctc ccaggtacgc atctgatcag gctctatttg caggacaacc agataaacca   1680

cattcctttg acagccttct caaatctgcg taagctggaa cggctggata tatccaacaa   1740

ccaactgcgg atgctgactc aaggggtttt tgataatctc tccaacctga agcagctcac   1800

tgctcggaat aacccttggt tttgtgactg cagtattaaa tgggtcacag aatggctcaa   1860

atatatccct tcatctctca acgtgcgggg tttcatgtgc caaggtcctg aacaagtccg   1920

ggggatggcc gtcagggaat taaatatgaa tcttttgtcc tgtcccacca cgacccccgg   1980

cctgcctctc ttcaccccag ccccaagtac agcttctccg accactcagc ctcccaccct   2040

ctctattcca aaccctagca gaagctacac gcctccaact cctaccacat cgaaacttcc   2100

cacgattcct gactgggatg gcagagaaag agtgacccca cctatttctg aacggatcca   2160

gctctctatc cattttgtga atgatacttc cattcaagtc agctggctct ctctcttcac   2220

cgtgatggca tacaaactca catgggtgaa aatgggccac agtttagtag ggggcatcgt   2280

tcaggagcgc atagtcagcg gtgagaagca acacctgagc ctggttaact tagagccccg   2340

atccacctat cggatttgtt tagtgccact ggatgctttt aactaccgcg cggtagaaga   2400

caccatttgt tcagaggcca ccacccatgc ctcctatctg aacaacggca gcaacacagc   2460

gtccagccat gagcagacga cgtcccacag catgggctcc ccctttctgc tggcgggctt   2520

gatcgggggc gcggtgatat ttgtgctggt ggtcttgctc agcgtctttt gctggcatat   2580

gcacaaaaag gggcgctaca cctcccagaa gtggaaatac aaccggggcc ggcggaaaga   2640

tgattattgc gaggcaggca ccaagaagga caactccatc ctggagatga cagaaaccag   2700

ttttcagatc gtctccttaa ataacgatca actccttaaa ggagatttca gactgcagcc   2760

catttacacc ccaaatgggg gcattaatta cacagactgc catatcccca acaacatgcg   2820

atactgcaac agcagcgtgc cagacctgga gcactgccat acgtgacagc cagaggccca   2880

gcgttatcaa ggcggacaat tagactcttg agaacacact cgtgtgtgca cataaagaca   2940

cgcagattac atttgataaa tgttacacag atgcatttgt gcatttgaat actctgtaat   3000

ttatacggtg tactatataa tgggatttaa aaaaagtgct atcttttcta tttcaagtta   3060

attacaaaca gttttgtaac tctttgcttt ttaaatctt                          3099


<210>  8533
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8533

Met Ser Pro Leu Gln Gly Glu Asp Ala Ala Val Arg Leu Gln Ile Glu 
1               5                   10                  15


Leu Asn Gln Glu Val Arg Arg Leu Ile Lys Ala Gly Leu Thr Tyr Lys 
            20                  25                  30


Arg Arg Arg Glu Phe Cys Leu Pro Thr Trp Ala Cys Val Asp Thr Ala 
        35                  40                  45


Asp Asn Leu Pro Ser Pro Val Ala Ser Val Glu Lys Phe Ser Leu Leu 
    50                  55                  60


Asn Phe Leu His Met Glu Asp Ser Ser Lys Glu Gly Asn Thr Gly 
65                  70                  75


<210>  8534
<211>  7294
<212>  DNA
<213>  Homo sapiens

<400>  8534
gcttctctag ggagtgtcag gcgcacacag ggttaagtta gttccctccc tggtaggagg     60

gagaggagga ggaggggaaa agcagcatac tgtctcaggc tgggtacctt gtagttagtt    120

gtacgttcga aacctgtcgc cgtcacttgc gcgtttggca ttatccattg tcaccgcgga    180

ggaacgagcg ctcgagatat catcagtgcc cgcaaatctc cgcgccaagg cgctgagcta    240

ctcctttccg aggtgcgcct ctggtcctcc gtccctggtg cccagcagcg gcgaggcggc    300

atctccgctc ccgccgccgt gtccaccgag ccctgggatc agggtggcag ttctcaacga    360

tgggcaggag ggacctcggc ggcgacccct aaaacaatac catgccccgg gatccccgct    420

gctgccgcgc cagcgtcttc cctttccacc tccctgaccc tgtcggattc ggatgagccc    480

attgcaagga gaagacgcag ccgtcagatt gcagattgag cttaaccaag aagttcgtag    540

gctaatcaag gctggcttga cctacaaaag aagaagagag ttctgcctgc ccacttgggc    600

ttgtgttgac acggctgata acttgccatc acctgttgcc agtgtggaaa aattctccct    660

gttgaatttt ttgcacatgg aggacagcag caaagagggc aacacaggct gataagacca    720

gagacagcag ggagattatt ttaccatacg ccctcaggac gttccctcta gctggagttc    780

tggacttcaa cagaacccca tccagtcatt ttgattttgc tgtttatttt ttttttcttt    840

ttctttttcc caccacattg tattttattt ccgtacttca gaaatgggcc tacagaccac    900

aaagtggccc agccatgggg cttttttcct gaagtcttgg cttatcattt ccctggggct    960

ctactcacag gtgtccaaac tcctggcctg ccctagtgtg tgccgctgcg acaggaactt   1020

tgtctactgt aatgagcgaa gcttgacctc agtgcctctt gggatcccgg agggcgtaac   1080

tgtactctac ctccacaaca accaaattaa taatgctgga tttcctgcag aactgcacaa   1140

tgtacagtcg gtgcacacgg tctacctgta tggcaaccaa ctggacgaat tccccatgaa   1200

ccttcccaag aatgtcagag ttctccattt gcaggaaaac aatattcaga ccatttcacg   1260

ggctgctctt gcccagctct tgaagcttga agagctgcac ctggatgaca actccatatc   1320

cacagtgggg gtggaagacg gggccttccg ggaggctatt agcctcaaat tgttgttttt   1380

gtctaagaat cacctgagca gtgtgcctgt tgggcttcct gtggacttgc aagagctgag   1440

agtggatgaa aatcgaattg ctgtcatatc cgacatggcc ttccagaatc tcacgagctt   1500

ggagcgtctt attgtggacg ggaacctcct gaccaacaag ggtatcgccg agggcacctt   1560

cagccatctc accaagctca aggaattttc aattgtacgt aattcgctgt cccaccctcc   1620

tcccgatctc ccaggtacgc atctgatcag gctctatttg caggacaacc agataaacca   1680

cattcctttg acagccttct caaatctgcg taagctggaa cggctggata tatccaacaa   1740

ccaactgcgg atgctgactc aaggggtttt tgataatctc tccaacctga agcagctcac   1800

tgctcggaat aacccttggt tttgtgactg cagtattaaa tgggtcacag aatggctcaa   1860

atatatccct tcatctctca acgtgcgggg tttcatgtgc caaggtcctg aacaagtccg   1920

ggggatggcc gtcagggaat taaatatgaa tcttttgtcc tgtcccacca cgacccccgg   1980

cctgcctctc ttcaccccag ccccaagtac agcttctccg accactcagc ctcccaccct   2040

ctctattcca aaccctagca gaagctacac gcctccaact cctaccacat cgaaacttcc   2100

cacgattcct gactgggatg gcagagaaag agtgacccca cctatttctg aacggatcca   2160

gctctctatc cattttgtga atgatacttc cattcaagtc agctggctct ctctcttcac   2220

cgtgatggca tacaaactca catgggtgaa aatgggccac agtttagtag ggggcatcgt   2280

tcaggagcgc atagtcagcg gtgagaagca acacctgagc ctggttaact tagagccccg   2340

atccacctat cggatttgtt tagtgccact ggatgctttt aactaccgcg cggtagaaga   2400

caccatttgt tcagaggcca ccacccatgc ctcctatctg aacaacggca gcaacacagc   2460

gtccagccat gagcagacga cgtcccacag catgggctcc ccctttctgc tggcgggctt   2520

gatcgggggc gcggtgatat ttgtgctggt ggtcttgctc agcgtctttt gctggcatat   2580

gcacaaaaag gggcgctaca cctcccagaa gtggaaatac aaccggggcc ggcggaaaga   2640

tgattattgc gaggcaggca ccaagaagga caactccatc ctggagatga cagaaaccag   2700

ttttcagatc gtctccttaa ataacgatca actccttaaa ggagatttca gactgcagcc   2760

catttacacc ccaaatgggg gcattaatta cacagactgc catatcccca acaacatgcg   2820

atactgcaac agcagcgtgc cagacctgga gcactgccat acgtgacagc cagaggccca   2880

gcgttatcaa ggcggacaat tagactcttg agaacacact cgtgtgtgca cataaagaca   2940

cgcagattac atttgataaa tgttacacag atgcatttgt gcatttgaat actctgtaat   3000

ttatacggtg tactatataa tgggatttaa aaaaagtgct atcttttcta tttcaagtta   3060

attacaaaca gttttgtaac tctttgcttt ttaaatctta aaaaaaaaaa agttgctgaa   3120

gtactgtaca gggttgtaca atgagaaccc aatgccaagg caaaaagaac gagtgatttt   3180

tccttaggat acacatcaac cactttgctg ttgaagctgt cagaataaat tcctggtggt   3240

cagatgaaag ggcagattaa atggactcat cagggtaaga ggaataatat gggtaaaaca   3300

agaaatggcc cgatagtttc acactattcc tatacctcca ggtccggaag acaggtaaaa   3360

aattctataa tgtaagaatg gaggtagtta ccctgatttg accctgtgtg ggaaatgctg   3420

aaagcaccag gaggaagccg gttcccgtga gataagttaa cccggcctga cagaatcaag   3480

aaaattgaga tgagatttga aaggacccga aaatgcaggg gttggctttc tgactgggaa   3540

cttaaaaatc actcttcatg cttccctggt cctatgtgat aacagagtta gagacttgag   3600

tctgatttca gtcatcttca gggaccagtc tgatgttgta gcaagaagac tccctttaaa   3660

agtgttactg ttcaaatcat atatcaggtt gaatcacatt caacagagat atattctaga   3720

atactttttt agaagaggct aataaaggga agaattatat tgaatggaat tatttttgat   3780

aatgagaatt atttgggtag attcactgag gctatgtcaa catgatattt agaccaacag   3840

gtgatcaatg tttggaaaat acaacaatga cttatttaaa aattaccctt cctgctattt   3900

agacaaaaac aactgatcag tggttctgtt atgtcagctg actttgttag tatcatgttg   3960

aaatagcttg aagtaatatc ttttatcccc ttgcaaattc ttgtcttcca atcatctccc   4020

atatattttc ataattagtt gtttatgaca cctttgtttt tctccctctg ttcagtattt   4080

caaggaaaat tatggatgcc agtcttggct gcacaagata tccattacgt acttatacat   4140

tttaaaatga gtactaattt tcactgctaa taattctgta aggacacatc aaagctggcc   4200

aaaataatga atttttttta aaaagcaata cctggtttcc accttggact gactttgatc   4260

ctgttccact tttgaaattt tatttgttcc ttttccatcg tggatgttcc tctactttgg   4320

caattgtgga gggctaatca atcttatgtt agcaggacaa cccatgaaaa acaagtcaga   4380

gagtgaaggc tttttcccct aatcctggca gagcagggcg tagaaaagag aggatgtccg   4440

tgcttaattc tagatacttt tgagacaaca ccttcagaaa acacataatt taatctttgc   4500

catccttaga tagagaaggg ctatagatca catacgttat caaaaactac tcccttggaa   4560

aaaatatctt tcgaaaatca aatttaaaca tttcactctg tgctgcatat ttcttttacc   4620

attgaccatt attataggga cccatgaagt aaatgtcaca atcatcttac tagctctctc   4680

tctctcagca aaataaaact gtgatgtgtc ttctttgtaa aagtttaggt ataaaatgct   4740

atgcaacttt ttctttatag taagagcttt attttcttta ataatatagc ccaacttata   4800

tgttttaatc tcccttgtcc ctcagaataa gcagaaaata taactgcagc tgtatgtcgt   4860

agacacaaga attgaaactg tgcagtcagt agagctgaac ttagctatga attaatttaa   4920

attaattcta aagtgactct ggtttccatt ttagtctatt agctagaggg ttttggctgt   4980

tgcttttttt aaagttaggt ccacacagtg aagggaaaag agtctgtgaa ggtgatcagt   5040

gtagcagtaa gacatctaaa atcaagacaa tgacatgggg gctttgtgta cttagctgga   5100

taattccctt ctactgtcct cttccccttg gctgtgtaga taaaattgtg cattcaaatg   5160

atggtacttt gacttttgag ggtttttatt tctgttattc acaaaatact cattctcatt   5220

tatgtatatt gtatgtttaa cccccagtgg gatttctggc tgctgaaacc actttgggcc   5280

aggaagaaca aggatgaaga ggttcctgtc atttcttatg gggttcacag aattatttgg   5340

ggcttaaatg gtacaatgga gacagtcatg tgcaatgctt aagatggtct gacagggtcc   5400

cttttgctgg aggtgttcct gaagagattg aacctagtaa caggctttat tttcaccttg   5460

tgtacaacat ggcaaagact gctaagatta aaatccgtct cccatttgtt acagcctcac   5520

ctgcaccagg atagaaagca cgtgatggaa tctgtgatgt ctaatgtgtc ttatgaaaat   5580

tgccaaacaa ctgtccctgg ggattctgct ttgattggca tttttagtca tgggaatgta   5640

tatttgctga tatatctgct ctgtgtttgg gcctctcttg ctgtcattat gatgtatttt   5700

gagatgatta gtcaagagtc aaggttgcga gtacaggcca agaccatggg aaaaaaagcc   5760

atgctcactg gccaataaag agcttgatgc tgcctggcca aatgaggtga ctcagataga   5820

atctgatccc attcagagct tggtaaatgt cactgtacag aagacattga aaaggaagag   5880

gcatagtcat gatcaaaagg atatattgac agttatctat agccagggta gttgttaata   5940

cctgcttgtt tggggagata tgtttgatta tagagagact ctgggccacc ctcaaacacc   6000

gtcagatgca ttagcagccc actgcatggg acaatcgcag gcagatacga ggaatgtatc   6060

ccctgcctat tttccttgtg taacaaatgg aaaacattct cccctgtgag aaataatgca   6120

atttctaatt atctggatgt tcgttgaaaa tatattagac attctccctg aggttaaaaa   6180

caaaaagtac gtgaccagtc tggtaagaag tattaatgaa gtagctaata ttacagcttc   6240

attttctact agcacctatc ataatggtct tagtcatttc acacaaatca gaacttcctt   6300

ccccaccagg gaggacaaca tcttcatgct gtgattgaag catccattca gaacacgagg   6360

caatattgca gtccacaggg aatggatgct tcacttgatc tccggacctt ggctgcagag   6420

gccatcgcag cttttgaaaa gtgaaggggt taattcccat tggtgtcttt gcttatagca   6480

tttttctcta acctataaca aggagacatt acattttact ttagaacatg agaatagcag   6540

ttttgctcat gacttaccat tccagctgca tgggaaagca aagcagaaaa cagtgcccca   6600

aatggaaaaa agatactcac acagaacaaa acagttcttg gtcttgttct tggtcttgtc   6660

aaaccttgcc tgatgctctt tctaaagtca aaatatgaat gctaagaagg cataacctac   6720

atccttctct gatttcttca gcagggtcaa aagacagtta ctagcaatgg ggaatgcttg   6780

tcactgtgga gaaagagttt tgtatatgtc tgataccgtt gttataacaa aacaaatttt   6840

tttactatag ttttttgttt tctacctgca cacccaccag aagagcacaa agcaaggcca   6900

ttgcaacagg catttaaaaa ttattatcaa acatgcacat gcttgtacac acacacacac   6960

acacacacaa acaggggcat ttgtaaaggt gtccctggaa tgtaagattt ataatgttta   7020

aggcaaggtg aaggcattgc caagtgtgtg tcgctcatag gactagtgta tattcactga   7080

aagttaacct gatgatttgt tattgtttga accatatgct gatttgcttc tggtttctgt   7140

ttagtgtgtt ctctctgata aggggctgaa agattctgca tcacacatcc tctgagacct   7200

accatgtcgc acactttgtt aatgacaaac ttcactctac actatacagt accttgttga   7260

tatattcagt aaagtcttat tttaaaagaa aacc                               7294


<210>  8535
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8535

Met Ser Pro Leu Gln Gly Glu Asp Ala Ala Val Arg Leu Gln Ile Glu 
1               5                   10                  15


Leu Asn Gln Glu Val Arg Arg Leu Ile Lys Ala Gly Leu Thr Tyr Lys 
            20                  25                  30


Arg Arg Arg Glu Phe Cys Leu Pro Thr Trp Ala Cys Val Asp Thr Ala 
        35                  40                  45


Asp Asn Leu Pro Ser Pro Val Ala Ser Val Glu Lys Phe Ser Leu Leu 
    50                  55                  60


Asn Phe Leu His Met Glu Asp Ser Ser Lys Glu Gly Asn Thr Gly 
65                  70                  75


<210>  8536
<211>  7412
<212>  DNA
<213>  Homo sapiens

<400>  8536
gcttctctag ggagtgtcag gcgcacacag ggttaagtta gttccctccc tggtaggagg     60

gagaggagga ggaggggaaa agcagcatac tgtctcaggc tgggtacctt gtagttagtt    120

gtacgttcga aacctgtcgc cgtcacttgc gcgtttggca ttatccattg tcaccgcgga    180

ggaacgagcg ctcgagatat catcagtgcc cgcaaatctc cgcgccaagg cgctgagcta    240

ctcctttccg aggtgcgcct ctggtcctcc gtccctggtg cccagcagcg gcgaggcggc    300

atctccgctc ccgccgccgt gtccaccgag ccctgggatc agggtggcag ttctcaacga    360

tgggcaggag ggacctcggc ggcgacccct aaaacaatac catgccccgg gatccccgct    420

gctgccgcgc cagcgtcttc cctttccacc tccctgaccc tgtcggattc ggatgagccc    480

attgcaagga gaagacgcag ccgtcagatt gcagattgag cttaaccaag aagttcgtag    540

gctaatcaag gctggcttga cctacaaaag aagaagagag ttctgcctgc ccacttgggc    600

ttgtgttgac acggctgata acttgccatc acctgttgcc agtgtggaaa aattctccct    660

gttgaatttt ttgcacatgg aggacagcag caaagagggc aacacaggct gataagacca    720

gagacagcag ggagattatt ttaccatacg ccctcaggac gttccctcta gctggagttc    780

tggacttcaa cagaacccca tccagtcatt ttgattttgc tgtttatttt ttttttcttt    840

ttctttttcc caccacattg tattttattt ccgtacttca gaaatgggcc tacagaccac    900

aaagtggccc agccatgggg cttttttcct gaagtcttgg cttatcattt ccctggggct    960

ctactcacag gtgtccaaac tcctggcctg ccctagtgtg tgccgctgcg acaggaactt   1020

tgtctactgt aatgagcgaa gcttgacctc agtgcctctt gggatcccgg agggcgtaac   1080

tgtactctac ctccacaaca accaaattaa taatgctgga tttcctgcag aactgcacaa   1140

tgtacagtcg gtgcacacgg tctacctgta tggcaaccaa ctggacgaat tccccatgaa   1200

ccttcccaag aatgtcagag ttctccattt gcaggaaaac aatattcaga ccatttcacg   1260

ggctgctctt gcccagctct tgaagcttga agagctgcac ctggatgaca actccatatc   1320

cacagtgggg gtggaagacg gggccttccg ggaggctatt agcctcaaat tgttgttttt   1380

gtctaagaat cacctgagca gtgtgcctgt tgggcttcct gtggacttgc aagagctgag   1440

agtggatgaa aatcgaattg ctgtcatatc cgacatggcc ttccagaatc tcacgagctt   1500

ggagcgtctt attgtggacg ggaacctcct gaccaacaag ggtatcgccg agggcacctt   1560

cagccatctc accaagctca aggaattttc aattgtacgt aattcgctgt cccaccctcc   1620

tcccgatctc ccaggtacgc atctgatcag gctctatttg caggacaacc agataaacca   1680

cattcctttg acagccttct caaatctgcg taagctggaa cggctggata tatccaacaa   1740

ccaactgcgg atgctgactc aaggggtttt tgataatctc tccaacctga agcagctcac   1800

tgctcggaat aacccttggt tttgtgactg cagtattaaa tgggtcacag aatggctcaa   1860

atatatccct tcatctctca acgtgcgggg tttcatgtgc caaggtcctg aacaagtccg   1920

ggggatggcc gtcagggaat taaatatgaa tcttttgtcc tgtcccacca cgacccccgg   1980

cctgcctctc ttcaccccag ccccaagtac agcttctccg accactcagc ctcccaccct   2040

ctctattcca aaccctagca gaagctacac gcctccaact cctaccacat cgaaacttcc   2100

cacgattcct gactgggatg gcagagaaag agtgacccca cctatttctg aacggatcca   2160

gctctctatc cattttgtga atgatacttc cattcaagtc agctggctct ctctcttcac   2220

cgtgatggca tacaaactca catgggtgaa aatgggccac agtttagtag ggggcatcgt   2280

tcaggagcgc atagtcagcg gtgagaagca acacctgagc ctggttaact tagagccccg   2340

atccacctat cggatttgtt tagtgccact ggatgctttt aactaccgcg cggtagaaga   2400

caccatttgt tcagaggcca ccacccatgc ctcctatctg aacaacggca gcaacacagc   2460

gtccagccat gagcagacga cgtcccacag catgggctcc ccctttctgc tggcgggctt   2520

gatcgggggc gcggtgatat ttgtgctggt ggtcttgctc agcgtctttt gctggcatat   2580

gcacaaaaag gggcgctaca cctcccagaa gtggaaatac aaccggggcc ggcggaaaga   2640

tgattattgc gaggcaggca ccaagaagga caactccatc ctggagatga cagaaaccag   2700

ttttcagatc gtctccttaa ataacgatca actccttaaa ggagatttca gactgcagcc   2760

catttacacc ccaaatgggg gcattaatta cacagactgc catatcccca acaacatgcg   2820

atactgcaac agcagcgtgc cagacctgga gcactgccat acgtgacagc cagaggccca   2880

gcgttatcaa ggcggacaat tagactcttg agaacacact cgtgtgtgca cataaagaca   2940

cgcagattac atttgataaa tgttacacag atgcatttgt gcatttgaat actctgtaat   3000

ttatacggtg tactatataa tgggatttaa aaaaagtgct atcttttcta tttcaagtta   3060

attacaaaca gttttgtaac tctttgcttt ttaaatctta aaaaaaaaaa agttgctgaa   3120

gtactgtaca gggttgtaca atgagaaccc aatgccaagg caaaaagaac gagtgatttt   3180

tccttaggat acacatcaac cactttgctg ttgaagctgt cagaataaat tcctggtggt   3240

cagatgaaag ggcagattaa atggactcat cagggtaaga ggaataatat gggtaaaaca   3300

agaaatggcc cgatagtttc acactattcc tatacctcca ggtccggaag acaggtaaaa   3360

aattctataa tgtaagaatg gaggtagtta ccctgatttg accctgtgtg ggaaatgctg   3420

aaagcaccag gaggaagccg gttcccgtga gataagttaa cccggcctga cagaatcaag   3480

aaaattgaga tgagatttga aaggacccga aaatgcaggg gttggctttc tgactgggaa   3540

cttaaaaatc actcttcatg cttccctggt cctatgtgat aacagagtta gagacttgag   3600

tctgatttca gtcatcttca gggaccagtc tgatgttgta gcaagaagac tccctttaaa   3660

agtgttactg ttcaaatcat atatcaggtt gaatcacatt caacagagat atattctaga   3720

atactttttt agaagaggct aataaaggga agaattatat tgaatggaat tatttttgat   3780

aatgagaatt atttgggtag attcactgag gctatgtcaa catgatattt agaccaacag   3840

gtgatcaatg tttggaaaat acaacaatga cttatttaaa aattaccctt cctgctattt   3900

agacaaaaac aactgatcag tggttctgtt atgtcagctg actttgttag tatcatgttg   3960

aaatagcttg aagtaatatc ttttatcccc ttgcaaattc ttgtcttcca atcatctccc   4020

atatattttc ataattagtt gtttatgaca cctttgtttt tctccctctg ttcagtattt   4080

caaggaaaat tatggatgcc agtcttggct gcacaagata tccattacgt acttatacat   4140

tttaaaatga gtactaattt tcactgctaa taattctgta aggacacatc aaagctggcc   4200

aaaataatga atttttttta aaaagcaata cctggtttcc accttggact gactttgatc   4260

ctgttccact tttgaaattt tatttgttcc ttttccatcg tggatgttcc tctactttgg   4320

caattgtgga gggctaatca atcttatgtt agcaggacaa cccatgaaaa acaagtcaga   4380

gagtgaaggc tttttcccct aatcctggca gagcagggcg tagaaaagag aggatgtccg   4440

tgcttaattc tagatacttt tgagacaaca ccttcagaaa acacataatt taatctttgc   4500

catccttaga tagagaaggg ctatagatca catacgttat caaaaactac tcccttggaa   4560

aaaatatctt tcgaaaatca aatttaaaca tttcactctg tgctgcatat ttcttttacc   4620

attgaccatt attataggga cccatgaagt aaatgtcaca atcatcttac tagctctctc   4680

tctctcagca aaataaaact gtgatgtgtc ttctttgtaa aagtttaggt ataaaatgct   4740

atgcaacttt ttctttatag taagagcttt attttcttta ataatatagc ccaacttata   4800

tgttttaatc tcccttgtcc ctcagaataa gcagaaaata taactgcagc tgtatgtcgt   4860

agacacaaga attgaaactg tgcagtcagt agagctgaac ttagctatga attaatttaa   4920

attaattcta aagtgactct ggtttccatt ttagtctatt agctagaggg ttttggctgt   4980

tgcttttttt aaagttaggt ccacacagtg aagggaaaag agtctgtgaa ggtgatcagt   5040

gtagcagtaa gacatctaaa atcaagacaa tgacatgggg gctttgtgta cttagctgga   5100

taattccctt ctactgtcct cttccccttg gctgtgtaga taaaattgtg cattcaaatg   5160

atggtacttt gacttttgag ggtttttatt tctgttattc acaaaatact cattctcatt   5220

tatgtatatt gtatgtttaa cccccagtgg gatttctggc tgctgaaacc actttgggcc   5280

aggaagaaca aggatgaaga ggttcctgtc atttcttatg gggttcacag aattatttgg   5340

ggcttaaatg gtacaatgga gacagtcatg tgcaatgctt aagatggtct gacagggtcc   5400

cttttgctgg aggtgttcct gaagagattg aacctagtaa caggctttat tttcaccttg   5460

tgtacaacat ggcaaagact gctaagatta aaatccgtct cccatttgtt acagcctcac   5520

ctgcaccagg atagaaagca cgtgatggaa tctgtgatgt ctaatgtgtc ttatgaaaat   5580

tgccaaacaa ctgtccctgg ggattctgct ttgattggca tttttagtca tgggaatgta   5640

tatttgctga tatatctgct ctgtgtttgg gcctctcttg ctgtcattat gatgtatttt   5700

gagatgatta gtcaagagtc aaggttgcga gtacaggcca agaccatggg aaaaaaagcc   5760

atgctcactg gccaataaag agcttgatgc tgcctggcca aatgaggtga ctcagataga   5820

atctgatccc attcagagct tggtaaatgt cactgtacag aagacattga aaaggaagag   5880

gcatagtcat gatcaaaagg atatattgac agttatctat agccagggta gttgttaata   5940

cctgcttgtt tggggagata tgtttgatta tagagagact ctgggccacc ctcaaacacc   6000

gtcagatgca ttagcagccc actgcatggg acaatcgcag gcagatacga ggaatgtatc   6060

ccctgcctat tttccttgtg taacaaatgg aaaacattct cccctgtgag aaataatgca   6120

atttctaatt atctggatgt tcgttgaaaa tatattagac attctccctg aggttaaaaa   6180

caaaaagtac gtgaccagtc tggtaagaag tattaatgaa gtagctaata ttacagcttc   6240

attttctact agcacctatc ataatggtct tagtcatttc acacaaatca gaacttcctt   6300

ccccaccagg gaggacaaca tcttcatgct gtgattgaag catccattca gaacacgagg   6360

caatattgca gtccacaggg aatggatgct tcacttgatc tccggacctt ggctgcagag   6420

gccatcgcag cttttgaaaa gtgaaggggt taattcccat tggtgtcttt gcttatagca   6480

tttttctcta acctataaca aggagacatt acattttact ttagaacatg agaatagcag   6540

ttttgctcat gacttaccat tccagctgca tgggaaagca aagcagaaaa cagtgcccca   6600

aatggaaaaa agatactcac acagaacaaa acagttcttg gtcttgttct tggtcttgtc   6660

aaaccttgcc tgatgctctt tctaaagtca aaatatgaat gctaagaagg cataacctac   6720

atccttctct gatttcttca gcagggtcaa aagacagtta ctagcaatgg ggaatgcttg   6780

tcactgtgga gaaagagttt tgtatatgtc tgataccgtt gttataacaa aacaaatttt   6840

tttactatag ttttttgttt tctacctgca cacccaccag aagagcacaa agcaaggcca   6900

ttgcaacagg catttaaaaa ttattatcaa acatgcacat gcttgtacac acacacacac   6960

acacacacaa acaggggcat ttgtaaaggt gtccctggaa tgtaagattt ataatgttta   7020

aggcaaggtg aaggcattgc caagtgtgtg tcgctcatag gactagtgta tattcactga   7080

aagttaacct gatgatttgt tattgtttga accatatgct gatttgcttc tggtttctgt   7140

ttagtgtgtt ctctctgata aggggctgaa agattctgca tcacacatcc tctgagacct   7200

accatgtcgc acactttgtt aatgacaaac ttcactctac actatacagt accttgttga   7260

tatattcagt aaagtcttat tttaaaagaa aaccacattg tgtttatctg agtaagttca   7320

ttgggataca gtcaatactt gtgctgttaa tgtagaagaa atgacgcagg agggcaggaa   7380

taaaagaggt aataggactt tcgtattctc ct                                 7412


<210>  8537
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8537

Met Ser Pro Leu Gln Gly Glu Asp Ala Ala Val Arg Leu Gln Ile Glu 
1               5                   10                  15


Leu Asn Gln Glu Val Arg Arg Leu Ile Lys Ala Gly Leu Thr Tyr Lys 
            20                  25                  30


Arg Arg Arg Glu Phe Cys Leu Pro Thr Trp Ala Cys Val Asp Thr Ala 
        35                  40                  45


Asp Asn Leu Pro Ser Pro Val Ala Ser Val Glu Lys Phe Ser Leu Leu 
    50                  55                  60


Asn Phe Leu His Met Glu Asp Ser Ser Lys Glu Gly Asn Thr Gly 
65                  70                  75


<210>  8538
<211>  701
<212>  DNA
<213>  Homo sapiens

<400>  8538
gtcgccgtca cttgcgcgtt tggcattatc cattgtcacc gcggaggaac gagcgctcga     60

gatatcatca gtgcccgcaa atctccgcgc caaggcgctg agctactcct ttccgagatt    120

gcagattgag cttaaccaag aagttcgtag gctaatcaag gctggcttga cctacaaaag    180

aagaagagag ttctgcctgc ccacttgggc ttgtgttgac acggctgata acttgccatc    240

acctgttgcc agtgtggaaa aattctccct gttgaatttt ttgcacatgg aggacagcag    300

caaagagggc aacacaggct gataagacca gagacagcag ggagattatt ttaccatacg    360

ccctcaggac gttccctcta gctggagttc tggacttcaa cagaacccca tccagtcatt    420

ttgattttgc tgtttatttt ttttttcttt ttctttttcc caccacattg tattttattt    480

ccgtacttca gaaatgggcc tacagaccac aaagtggccc agccatgggg cttttttcct    540

gaagtcttgg cttatcattt ccctggggct ctactcacag gtgtccaaac tcctggcctg    600

ccctagtgtg tgccgctgcg acaggaactt tgtctactgt aatgagcgaa gcttgacctc    660

agtgcctctt gggatcccgg agggcgtaac tgtactctac c                        701


<210>  8539
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  8539

Met Gly Leu Gln Thr Thr Lys Trp Pro Ser His Gly Ala Phe Phe Leu 
1               5                   10                  15


Lys Ser Trp Leu Ile Ile Ser Leu Gly Leu Tyr Ser Gln Val Ser Lys 
            20                  25                  30


Leu Leu Ala Cys Pro Ser Val Cys Arg Cys Asp Arg Asn Phe Val Tyr 
        35                  40                  45


Cys Asn Glu Arg Ser Leu Thr Ser Val Pro Leu Gly Ile Pro Glu Gly 
    50                  55                  60


Val Thr Val Leu 
65


<210>  8540
<211>  634
<212>  DNA
<213>  Homo sapiens

<400>  8540
agagcgcgag ggacggaggg agaggaggag cgcgggagct gcggaggcga tcccgcgaat     60

tcattactat tgcagattga gcttaaccaa gaagttcgta ggctaatcaa ggctggcttg    120

acctacaaaa gaagaagaga gttctgcctg cccacttggg cttgtgttga cacggctgat    180

aacttgccat cacctgttgc cagtgtggaa aaattctccc tgttgaattt tttgcacatg    240

gaggacagca gcaaagaggg caacacaggc tgataagacc agagacagca gggagattat    300

tttaccatac gccctcagga cgttccctct agctggagtt ctggacttca acagaacccc    360

atccagtcat tttgattttg ctgtttattt tttttttctt tttctttttc ccaccacatt    420

gtattttatt tccgtacttc agaaatgggc ctacagacca caaagtggcc cagccatggg    480

gcttttttcc tgaagtcttg gcttatcatt tccctggggc tctactcaca ggtgtccaaa    540

ctcctggcct gccctagtgt gtgccgctgc gacaggaact ttgtctactg taatgagcga    600

agcttgacct cagtgcctct tgggatcccg gagg                                634


<210>  8541
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  8541

Met Gly Leu Gln Thr Thr Lys Trp Pro Ser His Gly Ala Phe Phe Leu 
1               5                   10                  15


Lys Ser Trp Leu Ile Ile Ser Leu Gly Leu Tyr Ser Gln Val Ser Lys 
            20                  25                  30


Leu Leu Ala Cys Pro Ser Val Cys Arg Cys Asp Arg Asn Phe Val Tyr 
        35                  40                  45


Cys Asn Glu Arg Ser Leu Thr Ser Val Pro Leu Gly Ile Pro 
    50                  55                  60


<210>  8542
<211>  1771
<212>  DNA
<213>  Homo sapiens

<400>  8542
aggaactttg tctactgtaa tgagcgaagc ttgacctcaa attgttgttt ttgtctaaga     60

atcacctgag cagtgtgcct gttgggcttc ctgtggactt gcaagagctg agagtggatg    120

aaaatcgaat tgctgtcata tccgacatgg ccttccagaa tctcacgagc ttggagcgtc    180

ttattgtgga cgggaacctc ctgaccaaca agggtatcgc cgagggcacc ttcagccatc    240

tcaccaagct caaggaattt tcaattgtac gtaattcgct gtcccaccct cctcccgatc    300

tcccaggtac gcatctgatc aggctctatt tgcaggacaa ccagataaac cacattcctt    360

tgacagcctt ctcaaatctg cgtaagctgg aacggctgga tatatccaac aaccaactgc    420

ggatgctgac tcaaggggtt tttgataatc tctccaacct gaagcagctc actgctcgga    480

ataacccttg gttttgtgac tgcagtatta aatgggtcac agaatggctc aaatatatcc    540

cttcatctct caacgtgcgg ggtttcatgt gccaaggtcc tgaacaagtc cgggggatgg    600

ccgtcaggga attaaatatg aatcttttgt cctgtcccac cacgaccccc ggcctgcctc    660

tcttcacccc agccccaagt acagcttctc cgaccactca gcctcccacc ctctctattc    720

caaaccctag cagaagctac acgcctccaa ctcctaccac atcgaaactt cccacgattc    780

ctgactggga tggcagagaa agagtgaccc cacctatttc tgaacggatc cagctctcta    840

tccattttgt gaatgatact tccattcaag tcagctggct ctctctcttc accgtgatgg    900

catacaaact cacatgggtg aaaatgggcc acagtttagt agggggcatc gttcaggagc    960

gcatagtcag cggtgagaag caacacctga gcctggttaa cttagagccc cgatccacct   1020

atcggatttg tttagtgcca ctggatgctt ttaactaccg cgcggtagaa gacaccattt   1080

gttcagaggc caccacccat gcctcctatc tgaacaacgg cagcaacaca gcgtccagcc   1140

atgagcagac gacgtcccac agcatgggct ccccctttct gctggcgggc ttgatcgggg   1200

gcgcggtgat atttgtgctg gtggtcttgc tcagcgtctt ttgctggcat atgcacaaaa   1260

aggggcgcta cacctcccag aagtggaaat acaaccgggg ccggcggaaa gatgattatt   1320

gcgaggcagg caccaagaag gacaactcca tcctggagat gacagaaacc agttttcaga   1380

tcgtctcctt aaataacgat caactcctta aaggagattt cagactgcag cccatttaca   1440

ccccaaatgg gggcattaat tacacagact gccatatccc caacaacatg cgatactgca   1500

acagcagcgt gccagacctg gagcactgcc atacgtgaca gccagaggcc cagcgttatc   1560

aaggcggaca attagactct tgagaacaca ctcgtgtgtg cacataaaga cacgcagatt   1620

acatttgata aatgttacac agatgcattt gtgcatttga atactctgta atttatacgg   1680

tgtactatat aatgggattt aaaaaaagtg ctatcttttc tatttcaagt taattacaaa   1740

cagttttgta actctttgct ttttaaatct t                                  1771


<210>  8543
<211>  463
<212>  PRT
<213>  Homo sapiens

<400>  8543

Met Ala Phe Gln Asn Leu Thr Ser Leu Glu Arg Leu Ile Val Asp Gly 
1               5                   10                  15


Asn Leu Leu Thr Asn Lys Gly Ile Ala Glu Gly Thr Phe Ser His Leu 
            20                  25                  30


Thr Lys Leu Lys Glu Phe Ser Ile Val Arg Asn Ser Leu Ser His Pro 
        35                  40                  45


Pro Pro Asp Leu Pro Gly Thr His Leu Ile Arg Leu Tyr Leu Gln Asp 
    50                  55                  60


Asn Gln Ile Asn His Ile Pro Leu Thr Ala Phe Ser Asn Leu Arg Lys 
65                  70                  75                  80


Leu Glu Arg Leu Asp Ile Ser Asn Asn Gln Leu Arg Met Leu Thr Gln 
                85                  90                  95


Gly Val Phe Asp Asn Leu Ser Asn Leu Lys Gln Leu Thr Ala Arg Asn 
            100                 105                 110


Asn Pro Trp Phe Cys Asp Cys Ser Ile Lys Trp Val Thr Glu Trp Leu 
        115                 120                 125


Lys Tyr Ile Pro Ser Ser Leu Asn Val Arg Gly Phe Met Cys Gln Gly 
    130                 135                 140


Pro Glu Gln Val Arg Gly Met Ala Val Arg Glu Leu Asn Met Asn Leu 
145                 150                 155                 160


Leu Ser Cys Pro Thr Thr Thr Pro Gly Leu Pro Leu Phe Thr Pro Ala 
                165                 170                 175


Pro Ser Thr Ala Ser Pro Thr Thr Gln Pro Pro Thr Leu Ser Ile Pro 
            180                 185                 190


Asn Pro Ser Arg Ser Tyr Thr Pro Pro Thr Pro Thr Thr Ser Lys Leu 
        195                 200                 205


Pro Thr Ile Pro Asp Trp Asp Gly Arg Glu Arg Val Thr Pro Pro Ile 
    210                 215                 220


Ser Glu Arg Ile Gln Leu Ser Ile His Phe Val Asn Asp Thr Ser Ile 
225                 230                 235                 240


Gln Val Ser Trp Leu Ser Leu Phe Thr Val Met Ala Tyr Lys Leu Thr 
                245                 250                 255


Trp Val Lys Met Gly His Ser Leu Val Gly Gly Ile Val Gln Glu Arg 
            260                 265                 270


Ile Val Ser Gly Glu Lys Gln His Leu Ser Leu Val Asn Leu Glu Pro 
        275                 280                 285


Arg Ser Thr Tyr Arg Ile Cys Leu Val Pro Leu Asp Ala Phe Asn Tyr 
    290                 295                 300


Arg Ala Val Glu Asp Thr Ile Cys Ser Glu Ala Thr Thr His Ala Ser 
305                 310                 315                 320


Tyr Leu Asn Asn Gly Ser Asn Thr Ala Ser Ser His Glu Gln Thr Thr 
                325                 330                 335


Ser His Ser Met Gly Ser Pro Phe Leu Leu Ala Gly Leu Ile Gly Gly 
            340                 345                 350


Ala Val Ile Phe Val Leu Val Val Leu Leu Ser Val Phe Cys Trp His 
        355                 360                 365


Met His Lys Lys Gly Arg Tyr Thr Ser Gln Lys Trp Lys Tyr Asn Arg 
    370                 375                 380


Gly Arg Arg Lys Asp Asp Tyr Cys Glu Ala Gly Thr Lys Lys Asp Asn 
385                 390                 395                 400


Ser Ile Leu Glu Met Thr Glu Thr Ser Phe Gln Ile Val Ser Leu Asn 
                405                 410                 415


Asn Asp Gln Leu Leu Lys Gly Asp Phe Arg Leu Gln Pro Ile Tyr Thr 
            420                 425                 430


Pro Asn Gly Gly Ile Asn Tyr Thr Asp Cys His Ile Pro Asn Asn Met 
        435                 440                 445


Arg Tyr Cys Asn Ser Ser Val Pro Asp Leu Glu His Cys His Thr 
    450                 455                 460


<210>  8544
<211>  5966
<212>  DNA
<213>  Homo sapiens

<400>  8544
aggaactttg tctactgtaa tgagcgaagc ttgacctcaa attgttgttt ttgtctaaga     60

atcacctgag cagtgtgcct gttgggcttc ctgtggactt gcaagagctg agagtggatg    120

aaaatcgaat tgctgtcata tccgacatgg ccttccagaa tctcacgagc ttggagcgtc    180

ttattgtgga cgggaacctc ctgaccaaca agggtatcgc cgagggcacc ttcagccatc    240

tcaccaagct caaggaattt tcaattgtac gtaattcgct gtcccaccct cctcccgatc    300

tcccaggtac gcatctgatc aggctctatt tgcaggacaa ccagataaac cacattcctt    360

tgacagcctt ctcaaatctg cgtaagctgg aacggctgga tatatccaac aaccaactgc    420

ggatgctgac tcaaggggtt tttgataatc tctccaacct gaagcagctc actgctcgga    480

ataacccttg gttttgtgac tgcagtatta aatgggtcac agaatggctc aaatatatcc    540

cttcatctct caacgtgcgg ggtttcatgt gccaaggtcc tgaacaagtc cgggggatgg    600

ccgtcaggga attaaatatg aatcttttgt cctgtcccac cacgaccccc ggcctgcctc    660

tcttcacccc agccccaagt acagcttctc cgaccactca gcctcccacc ctctctattc    720

caaaccctag cagaagctac acgcctccaa ctcctaccac atcgaaactt cccacgattc    780

ctgactggga tggcagagaa agagtgaccc cacctatttc tgaacggatc cagctctcta    840

tccattttgt gaatgatact tccattcaag tcagctggct ctctctcttc accgtgatgg    900

catacaaact cacatgggtg aaaatgggcc acagtttagt agggggcatc gttcaggagc    960

gcatagtcag cggtgagaag caacacctga gcctggttaa cttagagccc cgatccacct   1020

atcggatttg tttagtgcca ctggatgctt ttaactaccg cgcggtagaa gacaccattt   1080

gttcagaggc caccacccat gcctcctatc tgaacaacgg cagcaacaca gcgtccagcc   1140

atgagcagac gacgtcccac agcatgggct ccccctttct gctggcgggc ttgatcgggg   1200

gcgcggtgat atttgtgctg gtggtcttgc tcagcgtctt ttgctggcat atgcacaaaa   1260

aggggcgcta cacctcccag aagtggaaat acaaccgggg ccggcggaaa gatgattatt   1320

gcgaggcagg caccaagaag gacaactcca tcctggagat gacagaaacc agttttcaga   1380

tcgtctcctt aaataacgat caactcctta aaggagattt cagactgcag cccatttaca   1440

ccccaaatgg gggcattaat tacacagact gccatatccc caacaacatg cgatactgca   1500

acagcagcgt gccagacctg gagcactgcc atacgtgaca gccagaggcc cagcgttatc   1560

aaggcggaca attagactct tgagaacaca ctcgtgtgtg cacataaaga cacgcagatt   1620

acatttgata aatgttacac agatgcattt gtgcatttga atactctgta atttatacgg   1680

tgtactatat aatgggattt aaaaaaagtg ctatcttttc tatttcaagt taattacaaa   1740

cagttttgta actctttgct ttttaaatct taaaaaaaaa aaagttgctg aagtactgta   1800

cagggttgta caatgagaac ccaatgccaa ggcaaaaaga acgagtgatt tttccttagg   1860

atacacatca accactttgc tgttgaagct gtcagaataa attcctggtg gtcagatgaa   1920

agggcagatt aaatggactc atcagggtaa gaggaataat atgggtaaaa caagaaatgg   1980

cccgatagtt tcacactatt cctatacctc caggtccgga agacaggtaa aaaattctat   2040

aatgtaagaa tggaggtagt taccctgatt tgaccctgtg tgggaaatgc tgaaagcacc   2100

aggaggaagc cggttcccgt gagataagtt aacccggcct gacagaatca agaaaattga   2160

gatgagattt gaaaggaccc gaaaatgcag gggttggctt tctgactggg aacttaaaaa   2220

tcactcttca tgcttccctg gtcctatgtg ataacagagt tagagacttg agtctgattt   2280

cagtcatctt cagggaccag tctgatgttg tagcaagaag actcccttta aaagtgttac   2340

tgttcaaatc atatatcagg ttgaatcaca ttcaacagag atatattcta gaatactttt   2400

ttagaagagg ctaataaagg gaagaattat attgaatgga attatttttg ataatgagaa   2460

ttatttgggt agattcactg aggctatgtc aacatgatat ttagaccaac aggtgatcaa   2520

tgtttggaaa atacaacaat gacttattta aaaattaccc ttcctgctat ttagacaaaa   2580

acaactgatc agtggttctg ttatgtcagc tgactttgtt agtatcatgt tgaaatagct   2640

tgaagtaata tcttttatcc ccttgcaaat tcttgtcttc caatcatctc ccatatattt   2700

tcataattag ttgtttatga cacctttgtt tttctccctc tgttcagtat ttcaaggaaa   2760

attatggatg ccagtcttgg ctgcacaaga tatccattac gtacttatac attttaaaat   2820

gagtactaat tttcactgct aataattctg taaggacaca tcaaagctgg ccaaaataat   2880

gaattttttt taaaaagcaa tacctggttt ccaccttgga ctgactttga tcctgttcca   2940

cttttgaaat tttatttgtt ccttttccat cgtggatgtt cctctacttt ggcaattgtg   3000

gagggctaat caatcttatg ttagcaggac aacccatgaa aaacaagtca gagagtgaag   3060

gctttttccc ctaatcctgg cagagcaggg cgtagaaaag agaggatgtc cgtgcttaat   3120

tctagatact tttgagacaa caccttcaga aaacacataa tttaatcttt gccatcctta   3180

gatagagaag ggctatagat cacatacgtt atcaaaaact actcccttgg aaaaaatatc   3240

tttcgaaaat caaatttaaa catttcactc tgtgctgcat atttctttta ccattgacca   3300

ttattatagg gacccatgaa gtaaatgtca caatcatctt actagctctc tctctctcag   3360

caaaataaaa ctgtgatgtg tcttctttgt aaaagtttag gtataaaatg ctatgcaact   3420

ttttctttat agtaagagct ttattttctt taataatata gcccaactta tatgttttaa   3480

tctcccttgt ccctcagaat aagcagaaaa tataactgca gctgtatgtc gtagacacaa   3540

gaattgaaac tgtgcagtca gtagagctga acttagctat gaattaattt aaattaattc   3600

taaagtgact ctggtttcca ttttagtcta ttagctagag ggttttggct gttgcttttt   3660

ttaaagttag gtccacacag tgaagggaaa agagtctgtg aaggtgatca gtgtagcagt   3720

aagacatcta aaatcaagac aatgacatgg gggctttgtg tacttagctg gataattccc   3780

ttctactgtc ctcttcccct tggctgtgta gataaaattg tgcattcaaa tgatggtact   3840

ttgacttttg agggttttta tttctgttat tcacaaaata ctcattctca tttatgtata   3900

ttgtatgttt aacccccagt gggatttctg gctgctgaaa ccactttggg ccaggaagaa   3960

caaggatgaa gaggttcctg tcatttctta tggggttcac agaattattt ggggcttaaa   4020

tggtacaatg gagacagtca tgtgcaatgc ttaagatggt ctgacagggt cccttttgct   4080

ggaggtgttc ctgaagagat tgaacctagt aacaggcttt attttcacct tgtgtacaac   4140

atggcaaaga ctgctaagat taaaatccgt ctcccatttg ttacagcctc acctgcacca   4200

ggatagaaag cacgtgatgg aatctgtgat gtctaatgtg tcttatgaaa attgccaaac   4260

aactgtccct ggggattctg ctttgattgg catttttagt catgggaatg tatatttgct   4320

gatatatctg ctctgtgttt gggcctctct tgctgtcatt atgatgtatt ttgagatgat   4380

tagtcaagag tcaaggttgc gagtacaggc caagaccatg ggaaaaaaag ccatgctcac   4440

tggccaataa agagcttgat gctgcctggc caaatgaggt gactcagata gaatctgatc   4500

ccattcagag cttggtaaat gtcactgtac agaagacatt gaaaaggaag aggcatagtc   4560

atgatcaaaa ggatatattg acagttatct atagccaggg tagttgttaa tacctgcttg   4620

tttggggaga tatgtttgat tatagagaga ctctgggcca ccctcaaaca ccgtcagatg   4680

cattagcagc ccactgcatg ggacaatcgc aggcagatac gaggaatgta tcccctgcct   4740

attttccttg tgtaacaaat ggaaaacatt ctcccctgtg agaaataatg caatttctaa   4800

ttatctggat gttcgttgaa aatatattag acattctccc tgaggttaaa aacaaaaagt   4860

acgtgaccag tctggtaaga agtattaatg aagtagctaa tattacagct tcattttcta   4920

ctagcaccta tcataatggt cttagtcatt tcacacaaat cagaacttcc ttccccacca   4980

gggaggacaa catcttcatg ctgtgattga agcatccatt cagaacacga ggcaatattg   5040

cagtccacag ggaatggatg cttcacttga tctccggacc ttggctgcag aggccatcgc   5100

agcttttgaa aagtgaaggg gttaattccc attggtgtct ttgcttatag catttttctc   5160

taacctataa caaggagaca ttacatttta ctttagaaca tgagaatagc agttttgctc   5220

atgacttacc attccagctg catgggaaag caaagcagaa aacagtgccc caaatggaaa   5280

aaagatactc acacagaaca aaacagttct tggtcttgtt cttggtcttg tcaaaccttg   5340

cctgatgctc tttctaaagt caaaatatga atgctaagaa ggcataacct acatccttct   5400

ctgatttctt cagcagggtc aaaagacagt tactagcaat ggggaatgct tgtcactgtg   5460

gagaaagagt tttgtatatg tctgataccg ttgttataac aaaacaaatt tttttactat   5520

agttttttgt tttctacctg cacacccacc agaagagcac aaagcaaggc cattgcaaca   5580

ggcatttaaa aattattatc aaacatgcac atgcttgtac acacacacac acacacacac   5640

aaacaggggc atttgtaaag gtgtccctgg aatgtaagat ttataatgtt taaggcaagg   5700

tgaaggcatt gccaagtgtg tgtcgctcat aggactagtg tatattcact gaaagttaac   5760

ctgatgattt gttattgttt gaaccatatg ctgatttgct tctggtttct gtttagtgtg   5820

ttctctctga taaggggctg aaagattctg catcacacat cctctgagac ctaccatgtc   5880

gcacactttg ttaatgacaa acttcactct acactataca gtaccttgtt gatatattca   5940

gtaaagtctt attttaaaag aaaacc                                        5966


<210>  8545
<211>  463
<212>  PRT
<213>  Homo sapiens

<400>  8545

Met Ala Phe Gln Asn Leu Thr Ser Leu Glu Arg Leu Ile Val Asp Gly 
1               5                   10                  15


Asn Leu Leu Thr Asn Lys Gly Ile Ala Glu Gly Thr Phe Ser His Leu 
            20                  25                  30


Thr Lys Leu Lys Glu Phe Ser Ile Val Arg Asn Ser Leu Ser His Pro 
        35                  40                  45


Pro Pro Asp Leu Pro Gly Thr His Leu Ile Arg Leu Tyr Leu Gln Asp 
    50                  55                  60


Asn Gln Ile Asn His Ile Pro Leu Thr Ala Phe Ser Asn Leu Arg Lys 
65                  70                  75                  80


Leu Glu Arg Leu Asp Ile Ser Asn Asn Gln Leu Arg Met Leu Thr Gln 
                85                  90                  95


Gly Val Phe Asp Asn Leu Ser Asn Leu Lys Gln Leu Thr Ala Arg Asn 
            100                 105                 110


Asn Pro Trp Phe Cys Asp Cys Ser Ile Lys Trp Val Thr Glu Trp Leu 
        115                 120                 125


Lys Tyr Ile Pro Ser Ser Leu Asn Val Arg Gly Phe Met Cys Gln Gly 
    130                 135                 140


Pro Glu Gln Val Arg Gly Met Ala Val Arg Glu Leu Asn Met Asn Leu 
145                 150                 155                 160


Leu Ser Cys Pro Thr Thr Thr Pro Gly Leu Pro Leu Phe Thr Pro Ala 
                165                 170                 175


Pro Ser Thr Ala Ser Pro Thr Thr Gln Pro Pro Thr Leu Ser Ile Pro 
            180                 185                 190


Asn Pro Ser Arg Ser Tyr Thr Pro Pro Thr Pro Thr Thr Ser Lys Leu 
        195                 200                 205


Pro Thr Ile Pro Asp Trp Asp Gly Arg Glu Arg Val Thr Pro Pro Ile 
    210                 215                 220


Ser Glu Arg Ile Gln Leu Ser Ile His Phe Val Asn Asp Thr Ser Ile 
225                 230                 235                 240


Gln Val Ser Trp Leu Ser Leu Phe Thr Val Met Ala Tyr Lys Leu Thr 
                245                 250                 255


Trp Val Lys Met Gly His Ser Leu Val Gly Gly Ile Val Gln Glu Arg 
            260                 265                 270


Ile Val Ser Gly Glu Lys Gln His Leu Ser Leu Val Asn Leu Glu Pro 
        275                 280                 285


Arg Ser Thr Tyr Arg Ile Cys Leu Val Pro Leu Asp Ala Phe Asn Tyr 
    290                 295                 300


Arg Ala Val Glu Asp Thr Ile Cys Ser Glu Ala Thr Thr His Ala Ser 
305                 310                 315                 320


Tyr Leu Asn Asn Gly Ser Asn Thr Ala Ser Ser His Glu Gln Thr Thr 
                325                 330                 335


Ser His Ser Met Gly Ser Pro Phe Leu Leu Ala Gly Leu Ile Gly Gly 
            340                 345                 350


Ala Val Ile Phe Val Leu Val Val Leu Leu Ser Val Phe Cys Trp His 
        355                 360                 365


Met His Lys Lys Gly Arg Tyr Thr Ser Gln Lys Trp Lys Tyr Asn Arg 
    370                 375                 380


Gly Arg Arg Lys Asp Asp Tyr Cys Glu Ala Gly Thr Lys Lys Asp Asn 
385                 390                 395                 400


Ser Ile Leu Glu Met Thr Glu Thr Ser Phe Gln Ile Val Ser Leu Asn 
                405                 410                 415


Asn Asp Gln Leu Leu Lys Gly Asp Phe Arg Leu Gln Pro Ile Tyr Thr 
            420                 425                 430


Pro Asn Gly Gly Ile Asn Tyr Thr Asp Cys His Ile Pro Asn Asn Met 
        435                 440                 445


Arg Tyr Cys Asn Ser Ser Val Pro Asp Leu Glu His Cys His Thr 
    450                 455                 460


<210>  8546
<211>  6084
<212>  DNA
<213>  Homo sapiens

<400>  8546
aggaactttg tctactgtaa tgagcgaagc ttgacctcaa attgttgttt ttgtctaaga     60

atcacctgag cagtgtgcct gttgggcttc ctgtggactt gcaagagctg agagtggatg    120

aaaatcgaat tgctgtcata tccgacatgg ccttccagaa tctcacgagc ttggagcgtc    180

ttattgtgga cgggaacctc ctgaccaaca agggtatcgc cgagggcacc ttcagccatc    240

tcaccaagct caaggaattt tcaattgtac gtaattcgct gtcccaccct cctcccgatc    300

tcccaggtac gcatctgatc aggctctatt tgcaggacaa ccagataaac cacattcctt    360

tgacagcctt ctcaaatctg cgtaagctgg aacggctgga tatatccaac aaccaactgc    420

ggatgctgac tcaaggggtt tttgataatc tctccaacct gaagcagctc actgctcgga    480

ataacccttg gttttgtgac tgcagtatta aatgggtcac agaatggctc aaatatatcc    540

cttcatctct caacgtgcgg ggtttcatgt gccaaggtcc tgaacaagtc cgggggatgg    600

ccgtcaggga attaaatatg aatcttttgt cctgtcccac cacgaccccc ggcctgcctc    660

tcttcacccc agccccaagt acagcttctc cgaccactca gcctcccacc ctctctattc    720

caaaccctag cagaagctac acgcctccaa ctcctaccac atcgaaactt cccacgattc    780

ctgactggga tggcagagaa agagtgaccc cacctatttc tgaacggatc cagctctcta    840

tccattttgt gaatgatact tccattcaag tcagctggct ctctctcttc accgtgatgg    900

catacaaact cacatgggtg aaaatgggcc acagtttagt agggggcatc gttcaggagc    960

gcatagtcag cggtgagaag caacacctga gcctggttaa cttagagccc cgatccacct   1020

atcggatttg tttagtgcca ctggatgctt ttaactaccg cgcggtagaa gacaccattt   1080

gttcagaggc caccacccat gcctcctatc tgaacaacgg cagcaacaca gcgtccagcc   1140

atgagcagac gacgtcccac agcatgggct ccccctttct gctggcgggc ttgatcgggg   1200

gcgcggtgat atttgtgctg gtggtcttgc tcagcgtctt ttgctggcat atgcacaaaa   1260

aggggcgcta cacctcccag aagtggaaat acaaccgggg ccggcggaaa gatgattatt   1320

gcgaggcagg caccaagaag gacaactcca tcctggagat gacagaaacc agttttcaga   1380

tcgtctcctt aaataacgat caactcctta aaggagattt cagactgcag cccatttaca   1440

ccccaaatgg gggcattaat tacacagact gccatatccc caacaacatg cgatactgca   1500

acagcagcgt gccagacctg gagcactgcc atacgtgaca gccagaggcc cagcgttatc   1560

aaggcggaca attagactct tgagaacaca ctcgtgtgtg cacataaaga cacgcagatt   1620

acatttgata aatgttacac agatgcattt gtgcatttga atactctgta atttatacgg   1680

tgtactatat aatgggattt aaaaaaagtg ctatcttttc tatttcaagt taattacaaa   1740

cagttttgta actctttgct ttttaaatct taaaaaaaaa aaagttgctg aagtactgta   1800

cagggttgta caatgagaac ccaatgccaa ggcaaaaaga acgagtgatt tttccttagg   1860

atacacatca accactttgc tgttgaagct gtcagaataa attcctggtg gtcagatgaa   1920

agggcagatt aaatggactc atcagggtaa gaggaataat atgggtaaaa caagaaatgg   1980

cccgatagtt tcacactatt cctatacctc caggtccgga agacaggtaa aaaattctat   2040

aatgtaagaa tggaggtagt taccctgatt tgaccctgtg tgggaaatgc tgaaagcacc   2100

aggaggaagc cggttcccgt gagataagtt aacccggcct gacagaatca agaaaattga   2160

gatgagattt gaaaggaccc gaaaatgcag gggttggctt tctgactggg aacttaaaaa   2220

tcactcttca tgcttccctg gtcctatgtg ataacagagt tagagacttg agtctgattt   2280

cagtcatctt cagggaccag tctgatgttg tagcaagaag actcccttta aaagtgttac   2340

tgttcaaatc atatatcagg ttgaatcaca ttcaacagag atatattcta gaatactttt   2400

ttagaagagg ctaataaagg gaagaattat attgaatgga attatttttg ataatgagaa   2460

ttatttgggt agattcactg aggctatgtc aacatgatat ttagaccaac aggtgatcaa   2520

tgtttggaaa atacaacaat gacttattta aaaattaccc ttcctgctat ttagacaaaa   2580

acaactgatc agtggttctg ttatgtcagc tgactttgtt agtatcatgt tgaaatagct   2640

tgaagtaata tcttttatcc ccttgcaaat tcttgtcttc caatcatctc ccatatattt   2700

tcataattag ttgtttatga cacctttgtt tttctccctc tgttcagtat ttcaaggaaa   2760

attatggatg ccagtcttgg ctgcacaaga tatccattac gtacttatac attttaaaat   2820

gagtactaat tttcactgct aataattctg taaggacaca tcaaagctgg ccaaaataat   2880

gaattttttt taaaaagcaa tacctggttt ccaccttgga ctgactttga tcctgttcca   2940

cttttgaaat tttatttgtt ccttttccat cgtggatgtt cctctacttt ggcaattgtg   3000

gagggctaat caatcttatg ttagcaggac aacccatgaa aaacaagtca gagagtgaag   3060

gctttttccc ctaatcctgg cagagcaggg cgtagaaaag agaggatgtc cgtgcttaat   3120

tctagatact tttgagacaa caccttcaga aaacacataa tttaatcttt gccatcctta   3180

gatagagaag ggctatagat cacatacgtt atcaaaaact actcccttgg aaaaaatatc   3240

tttcgaaaat caaatttaaa catttcactc tgtgctgcat atttctttta ccattgacca   3300

ttattatagg gacccatgaa gtaaatgtca caatcatctt actagctctc tctctctcag   3360

caaaataaaa ctgtgatgtg tcttctttgt aaaagtttag gtataaaatg ctatgcaact   3420

ttttctttat agtaagagct ttattttctt taataatata gcccaactta tatgttttaa   3480

tctcccttgt ccctcagaat aagcagaaaa tataactgca gctgtatgtc gtagacacaa   3540

gaattgaaac tgtgcagtca gtagagctga acttagctat gaattaattt aaattaattc   3600

taaagtgact ctggtttcca ttttagtcta ttagctagag ggttttggct gttgcttttt   3660

ttaaagttag gtccacacag tgaagggaaa agagtctgtg aaggtgatca gtgtagcagt   3720

aagacatcta aaatcaagac aatgacatgg gggctttgtg tacttagctg gataattccc   3780

ttctactgtc ctcttcccct tggctgtgta gataaaattg tgcattcaaa tgatggtact   3840

ttgacttttg agggttttta tttctgttat tcacaaaata ctcattctca tttatgtata   3900

ttgtatgttt aacccccagt gggatttctg gctgctgaaa ccactttggg ccaggaagaa   3960

caaggatgaa gaggttcctg tcatttctta tggggttcac agaattattt ggggcttaaa   4020

tggtacaatg gagacagtca tgtgcaatgc ttaagatggt ctgacagggt cccttttgct   4080

ggaggtgttc ctgaagagat tgaacctagt aacaggcttt attttcacct tgtgtacaac   4140

atggcaaaga ctgctaagat taaaatccgt ctcccatttg ttacagcctc acctgcacca   4200

ggatagaaag cacgtgatgg aatctgtgat gtctaatgtg tcttatgaaa attgccaaac   4260

aactgtccct ggggattctg ctttgattgg catttttagt catgggaatg tatatttgct   4320

gatatatctg ctctgtgttt gggcctctct tgctgtcatt atgatgtatt ttgagatgat   4380

tagtcaagag tcaaggttgc gagtacaggc caagaccatg ggaaaaaaag ccatgctcac   4440

tggccaataa agagcttgat gctgcctggc caaatgaggt gactcagata gaatctgatc   4500

ccattcagag cttggtaaat gtcactgtac agaagacatt gaaaaggaag aggcatagtc   4560

atgatcaaaa ggatatattg acagttatct atagccaggg tagttgttaa tacctgcttg   4620

tttggggaga tatgtttgat tatagagaga ctctgggcca ccctcaaaca ccgtcagatg   4680

cattagcagc ccactgcatg ggacaatcgc aggcagatac gaggaatgta tcccctgcct   4740

attttccttg tgtaacaaat ggaaaacatt ctcccctgtg agaaataatg caatttctaa   4800

ttatctggat gttcgttgaa aatatattag acattctccc tgaggttaaa aacaaaaagt   4860

acgtgaccag tctggtaaga agtattaatg aagtagctaa tattacagct tcattttcta   4920

ctagcaccta tcataatggt cttagtcatt tcacacaaat cagaacttcc ttccccacca   4980

gggaggacaa catcttcatg ctgtgattga agcatccatt cagaacacga ggcaatattg   5040

cagtccacag ggaatggatg cttcacttga tctccggacc ttggctgcag aggccatcgc   5100

agcttttgaa aagtgaaggg gttaattccc attggtgtct ttgcttatag catttttctc   5160

taacctataa caaggagaca ttacatttta ctttagaaca tgagaatagc agttttgctc   5220

atgacttacc attccagctg catgggaaag caaagcagaa aacagtgccc caaatggaaa   5280

aaagatactc acacagaaca aaacagttct tggtcttgtt cttggtcttg tcaaaccttg   5340

cctgatgctc tttctaaagt caaaatatga atgctaagaa ggcataacct acatccttct   5400

ctgatttctt cagcagggtc aaaagacagt tactagcaat ggggaatgct tgtcactgtg   5460

gagaaagagt tttgtatatg tctgataccg ttgttataac aaaacaaatt tttttactat   5520

agttttttgt tttctacctg cacacccacc agaagagcac aaagcaaggc cattgcaaca   5580

ggcatttaaa aattattatc aaacatgcac atgcttgtac acacacacac acacacacac   5640

aaacaggggc atttgtaaag gtgtccctgg aatgtaagat ttataatgtt taaggcaagg   5700

tgaaggcatt gccaagtgtg tgtcgctcat aggactagtg tatattcact gaaagttaac   5760

ctgatgattt gttattgttt gaaccatatg ctgatttgct tctggtttct gtttagtgtg   5820

ttctctctga taaggggctg aaagattctg catcacacat cctctgagac ctaccatgtc   5880

gcacactttg ttaatgacaa acttcactct acactataca gtaccttgtt gatatattca   5940

gtaaagtctt attttaaaag aaaaccacat tgtgtttatc tgagtaagtt cattgggata   6000

cagtcaatac ttgtgctgtt aatgtagaag aaatgacgca ggagggcagg aataaaagag   6060

gtaataggac tttcgtattc tcct                                          6084


<210>  8547
<211>  463
<212>  PRT
<213>  Homo sapiens

<400>  8547

Met Ala Phe Gln Asn Leu Thr Ser Leu Glu Arg Leu Ile Val Asp Gly 
1               5                   10                  15


Asn Leu Leu Thr Asn Lys Gly Ile Ala Glu Gly Thr Phe Ser His Leu 
            20                  25                  30


Thr Lys Leu Lys Glu Phe Ser Ile Val Arg Asn Ser Leu Ser His Pro 
        35                  40                  45


Pro Pro Asp Leu Pro Gly Thr His Leu Ile Arg Leu Tyr Leu Gln Asp 
    50                  55                  60


Asn Gln Ile Asn His Ile Pro Leu Thr Ala Phe Ser Asn Leu Arg Lys 
65                  70                  75                  80


Leu Glu Arg Leu Asp Ile Ser Asn Asn Gln Leu Arg Met Leu Thr Gln 
                85                  90                  95


Gly Val Phe Asp Asn Leu Ser Asn Leu Lys Gln Leu Thr Ala Arg Asn 
            100                 105                 110


Asn Pro Trp Phe Cys Asp Cys Ser Ile Lys Trp Val Thr Glu Trp Leu 
        115                 120                 125


Lys Tyr Ile Pro Ser Ser Leu Asn Val Arg Gly Phe Met Cys Gln Gly 
    130                 135                 140


Pro Glu Gln Val Arg Gly Met Ala Val Arg Glu Leu Asn Met Asn Leu 
145                 150                 155                 160


Leu Ser Cys Pro Thr Thr Thr Pro Gly Leu Pro Leu Phe Thr Pro Ala 
                165                 170                 175


Pro Ser Thr Ala Ser Pro Thr Thr Gln Pro Pro Thr Leu Ser Ile Pro 
            180                 185                 190


Asn Pro Ser Arg Ser Tyr Thr Pro Pro Thr Pro Thr Thr Ser Lys Leu 
        195                 200                 205


Pro Thr Ile Pro Asp Trp Asp Gly Arg Glu Arg Val Thr Pro Pro Ile 
    210                 215                 220


Ser Glu Arg Ile Gln Leu Ser Ile His Phe Val Asn Asp Thr Ser Ile 
225                 230                 235                 240


Gln Val Ser Trp Leu Ser Leu Phe Thr Val Met Ala Tyr Lys Leu Thr 
                245                 250                 255


Trp Val Lys Met Gly His Ser Leu Val Gly Gly Ile Val Gln Glu Arg 
            260                 265                 270


Ile Val Ser Gly Glu Lys Gln His Leu Ser Leu Val Asn Leu Glu Pro 
        275                 280                 285


Arg Ser Thr Tyr Arg Ile Cys Leu Val Pro Leu Asp Ala Phe Asn Tyr 
    290                 295                 300


Arg Ala Val Glu Asp Thr Ile Cys Ser Glu Ala Thr Thr His Ala Ser 
305                 310                 315                 320


Tyr Leu Asn Asn Gly Ser Asn Thr Ala Ser Ser His Glu Gln Thr Thr 
                325                 330                 335


Ser His Ser Met Gly Ser Pro Phe Leu Leu Ala Gly Leu Ile Gly Gly 
            340                 345                 350


Ala Val Ile Phe Val Leu Val Val Leu Leu Ser Val Phe Cys Trp His 
        355                 360                 365


Met His Lys Lys Gly Arg Tyr Thr Ser Gln Lys Trp Lys Tyr Asn Arg 
    370                 375                 380


Gly Arg Arg Lys Asp Asp Tyr Cys Glu Ala Gly Thr Lys Lys Asp Asn 
385                 390                 395                 400


Ser Ile Leu Glu Met Thr Glu Thr Ser Phe Gln Ile Val Ser Leu Asn 
                405                 410                 415


Asn Asp Gln Leu Leu Lys Gly Asp Phe Arg Leu Gln Pro Ile Tyr Thr 
            420                 425                 430


Pro Asn Gly Gly Ile Asn Tyr Thr Asp Cys His Ile Pro Asn Asn Met 
        435                 440                 445


Arg Tyr Cys Asn Ser Ser Val Pro Asp Leu Glu His Cys His Thr 
    450                 455                 460


<210>  8548
<211>  2877
<212>  DNA
<213>  Homo sapiens

<400>  8548
acggcagcaa cacagcgtcc agccatgagc agacgacgtc ccacagcatg ggctccccct     60

ttctgctggc gggcttgatc gggggcgcgg tgatatttgt gctggtggtc ttgctcagcg    120

tcttttgctg gcatatgcac aaaaaggggc gctacacctc ccagaagtgg aaatacaacc    180

ggggccggcg gaaagatgat tattgcgagg caggcaccaa gaaggacaac tccatcctgg    240

agatgacaga aaccagtttt cagatcgtct ccttaaataa cgatcaactc cttaaaggag    300

atttcagact gcagcccatt tacaccccaa atgggggcat taattacaca gactgccata    360

tccccaacaa catgcgatac tgcaacagca gcgtgccaga cctggagcac tgccatacgt    420

gacagccaga ggcccagcgt tatcaaggcg gacaattaga ctcttgagaa cacactcgtg    480

tgtgcacata aagacacgca gattacattt gataaatgtt acacagatgc atttgtgcat    540

ttgaatactc tgtaatttat acggtgtact atataatggg atttaaaaaa agtgctatct    600

tttctatttc aagttaatta caaacagttt tgtaactctt tgctttttaa atcttaaaaa    660

aaaaaaagtt gctgaagtac tgtacagggt tgtacaatga gaacccaatg ccaaggcaaa    720

aagaacgagt gatttttcct taggatacac atcaaccact ttgctgttga agctgtcaga    780

ataaattcct ggtggtcaga tgaaagggca gattaaatgg actcatcagg tgggatttct    840

ggctgctgaa accactttgg gccaggaaga acaaggatga agaggttcct gtcatttctt    900

atggggttca cagaattatt tggggcttaa atggtacaat ggagacagtc atgtgcaatg    960

cttaagatgg tctgacaggg tcccttttgc tggaggtgtt cctgaagaga ttgaacctag   1020

taacaggctt tattttcacc ttgtgtacaa catggcaaag actgctaaga ttaaaatccg   1080

tctcccattt gttacagcct cacctgcacc aggatagaaa gcacgtgatg gaatctgtga   1140

tgtctaatgt gtcttatgaa aattgccaaa caactgtccc tggggattct gctttgattg   1200

gcatttttag tcatgggaat gtatatttgc tgatatatct gctctgtgtt tgggcctctc   1260

ttgctgtcat tatgatgtat tttgagatga ttagtcaaga gtcaaggttg cgagtacagg   1320

ccaagaccat gggaaaaaaa gccatgctca ctggccaata aagagcttga tgctgcctgg   1380

ccaaatgagg tgactcagat agaatctgat cccattcaga gcttggtaaa tgtcactgta   1440

cagaagacat tgaaaaggaa gaggcatagt catgatcaaa aggatatatt gacagttatc   1500

tatagccagg gtagttgtta atacctgctt gtttggggag atatgtttga ttatagagag   1560

actctgggcc accctcaaac accgtcagat gcattagcag cccactgcat gggacaatcg   1620

caggcagata cgaggaatgt atcccctgcc tattttcctt gtgtaacaaa tggaaaacat   1680

tctcccctgt gagaaataat gcaatttcta attatctgga tgttcgttga aaatatatta   1740

gacattctcc ctgaggttaa aaacaaaaag tacgtgacca gtctggtaag aagtattaat   1800

gaagtagcta atattacagc ttcattttct actagcacct atcataatgg tcttagtcat   1860

ttcacacaaa tcagaacttc cttccccacc agggaggaca acatcttcat gctgtgattg   1920

aagcatccat tcagaacacg aggcaatatt gcagtccaca gggaatggat gcttcacttg   1980

atctccggac cttggctgca gaggccatcg cagcttttga aaagtgaagg ggttaattcc   2040

cattggtgtc tttgcttata gcatttttct ctaacctata acaaggagac attacatttt   2100

actttagaac atgagaatag cagttttgct catgacttac cattccagct gcatgggaaa   2160

gcaaagcaga aaacagtgcc ccaaatggaa aaaagatact cacacagaac aaaacagttc   2220

ttggtcttgt tcttggtctt gtcaaacctt gcctgatgct ctttctaaag tcaaaatatg   2280

aatgctaaga aggcataacc tacatccttc tctgatttct tcagcagggt caaaagacag   2340

ttactagcaa tggggaatgc ttgtcactgt ggagaaagag ttttgtatat gtctgatacc   2400

gttgttataa caaaacaaat ttttttacta tagttttttg ttttctacct gcacacccac   2460

cagaagagca caaagcaagg ccattgcaac aggcatttaa aaattattat caaacatgca   2520

catgcttgta cacacacaca cacacacaca caaacagggg catttgtaaa ggtgtccctg   2580

gaatgtaaga tttataatgt ttaaggcaag gtgaaggcat tgccaagtgt gtgtcgctca   2640

taggactagt gtatattcac tgaaagttaa cctgatgatt tgttattgtt tgaaccatat   2700

gctgatttgc ttctggtttc tgtttagtgt gttctctctg ataaggggct gaaagattct   2760

gcatcacaca tcctctgaga cctaccatgt cgcacacttt gttaatgaca aacttcactc   2820

tacactatac agtaccttgt tgatatattc agtaaagtct tattttaaaa gaaaacc      2877


<210>  8549
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  8549

Met Gly Ser Pro Phe Leu Leu Ala Gly Leu Ile Gly Gly Ala Val Ile 
1               5                   10                  15


Phe Val Leu Val Val Leu Leu Ser Val Phe Cys Trp His Met His Lys 
            20                  25                  30


Lys Gly Arg Tyr Thr Ser Gln Lys Trp Lys Tyr Asn Arg Gly Arg Arg 
        35                  40                  45


Lys Asp Asp Tyr Cys Glu Ala Gly Thr Lys Lys Asp Asn Ser Ile Leu 
    50                  55                  60


Glu Met Thr Glu Thr Ser Phe Gln Ile Val Ser Leu Asn Asn Asp Gln 
65                  70                  75                  80


Leu Leu Lys Gly Asp Phe Arg Leu Gln Pro Ile Tyr Thr Pro Asn Gly 
                85                  90                  95


Gly Ile Asn Tyr Thr Asp Cys His Ile Pro Asn Asn Met Arg Tyr Cys 
            100                 105                 110


Asn Ser Ser Val Pro Asp Leu Glu His Cys His Thr 
        115                 120


<210>  8550
<211>  2995
<212>  DNA
<213>  Homo sapiens

<400>  8550
acggcagcaa cacagcgtcc agccatgagc agacgacgtc ccacagcatg ggctccccct     60

ttctgctggc gggcttgatc gggggcgcgg tgatatttgt gctggtggtc ttgctcagcg    120

tcttttgctg gcatatgcac aaaaaggggc gctacacctc ccagaagtgg aaatacaacc    180

ggggccggcg gaaagatgat tattgcgagg caggcaccaa gaaggacaac tccatcctgg    240

agatgacaga aaccagtttt cagatcgtct ccttaaataa cgatcaactc cttaaaggag    300

atttcagact gcagcccatt tacaccccaa atgggggcat taattacaca gactgccata    360

tccccaacaa catgcgatac tgcaacagca gcgtgccaga cctggagcac tgccatacgt    420

gacagccaga ggcccagcgt tatcaaggcg gacaattaga ctcttgagaa cacactcgtg    480

tgtgcacata aagacacgca gattacattt gataaatgtt acacagatgc atttgtgcat    540

ttgaatactc tgtaatttat acggtgtact atataatggg atttaaaaaa agtgctatct    600

tttctatttc aagttaatta caaacagttt tgtaactctt tgctttttaa atcttaaaaa    660

aaaaaaagtt gctgaagtac tgtacagggt tgtacaatga gaacccaatg ccaaggcaaa    720

aagaacgagt gatttttcct taggatacac atcaaccact ttgctgttga agctgtcaga    780

ataaattcct ggtggtcaga tgaaagggca gattaaatgg actcatcagg tgggatttct    840

ggctgctgaa accactttgg gccaggaaga acaaggatga agaggttcct gtcatttctt    900

atggggttca cagaattatt tggggcttaa atggtacaat ggagacagtc atgtgcaatg    960

cttaagatgg tctgacaggg tcccttttgc tggaggtgtt cctgaagaga ttgaacctag   1020

taacaggctt tattttcacc ttgtgtacaa catggcaaag actgctaaga ttaaaatccg   1080

tctcccattt gttacagcct cacctgcacc aggatagaaa gcacgtgatg gaatctgtga   1140

tgtctaatgt gtcttatgaa aattgccaaa caactgtccc tggggattct gctttgattg   1200

gcatttttag tcatgggaat gtatatttgc tgatatatct gctctgtgtt tgggcctctc   1260

ttgctgtcat tatgatgtat tttgagatga ttagtcaaga gtcaaggttg cgagtacagg   1320

ccaagaccat gggaaaaaaa gccatgctca ctggccaata aagagcttga tgctgcctgg   1380

ccaaatgagg tgactcagat agaatctgat cccattcaga gcttggtaaa tgtcactgta   1440

cagaagacat tgaaaaggaa gaggcatagt catgatcaaa aggatatatt gacagttatc   1500

tatagccagg gtagttgtta atacctgctt gtttggggag atatgtttga ttatagagag   1560

actctgggcc accctcaaac accgtcagat gcattagcag cccactgcat gggacaatcg   1620

caggcagata cgaggaatgt atcccctgcc tattttcctt gtgtaacaaa tggaaaacat   1680

tctcccctgt gagaaataat gcaatttcta attatctgga tgttcgttga aaatatatta   1740

gacattctcc ctgaggttaa aaacaaaaag tacgtgacca gtctggtaag aagtattaat   1800

gaagtagcta atattacagc ttcattttct actagcacct atcataatgg tcttagtcat   1860

ttcacacaaa tcagaacttc cttccccacc agggaggaca acatcttcat gctgtgattg   1920

aagcatccat tcagaacacg aggcaatatt gcagtccaca gggaatggat gcttcacttg   1980

atctccggac cttggctgca gaggccatcg cagcttttga aaagtgaagg ggttaattcc   2040

cattggtgtc tttgcttata gcatttttct ctaacctata acaaggagac attacatttt   2100

actttagaac atgagaatag cagttttgct catgacttac cattccagct gcatgggaaa   2160

gcaaagcaga aaacagtgcc ccaaatggaa aaaagatact cacacagaac aaaacagttc   2220

ttggtcttgt tcttggtctt gtcaaacctt gcctgatgct ctttctaaag tcaaaatatg   2280

aatgctaaga aggcataacc tacatccttc tctgatttct tcagcagggt caaaagacag   2340

ttactagcaa tggggaatgc ttgtcactgt ggagaaagag ttttgtatat gtctgatacc   2400

gttgttataa caaaacaaat ttttttacta tagttttttg ttttctacct gcacacccac   2460

cagaagagca caaagcaagg ccattgcaac aggcatttaa aaattattat caaacatgca   2520

catgcttgta cacacacaca cacacacaca caaacagggg catttgtaaa ggtgtccctg   2580

gaatgtaaga tttataatgt ttaaggcaag gtgaaggcat tgccaagtgt gtgtcgctca   2640

taggactagt gtatattcac tgaaagttaa cctgatgatt tgttattgtt tgaaccatat   2700

gctgatttgc ttctggtttc tgtttagtgt gttctctctg ataaggggct gaaagattct   2760

gcatcacaca tcctctgaga cctaccatgt cgcacacttt gttaatgaca aacttcactc   2820

tacactatac agtaccttgt tgatatattc agtaaagtct tattttaaaa gaaaaccaca   2880

ttgtgtttat ctgagtaagt tcattgggat acagtcaata cttgtgctgt taatgtagaa   2940

gaaatgacgc aggagggcag gaataaaaga ggtaatagga ctttcgtatt ctcct        2995


<210>  8551
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  8551

Met Gly Ser Pro Phe Leu Leu Ala Gly Leu Ile Gly Gly Ala Val Ile 
1               5                   10                  15


Phe Val Leu Val Val Leu Leu Ser Val Phe Cys Trp His Met His Lys 
            20                  25                  30


Lys Gly Arg Tyr Thr Ser Gln Lys Trp Lys Tyr Asn Arg Gly Arg Arg 
        35                  40                  45


Lys Asp Asp Tyr Cys Glu Ala Gly Thr Lys Lys Asp Asn Ser Ile Leu 
    50                  55                  60


Glu Met Thr Glu Thr Ser Phe Gln Ile Val Ser Leu Asn Asn Asp Gln 
65                  70                  75                  80


Leu Leu Lys Gly Asp Phe Arg Leu Gln Pro Ile Tyr Thr Pro Asn Gly 
                85                  90                  95


Gly Ile Asn Tyr Thr Asp Cys His Ile Pro Asn Asn Met Arg Tyr Cys 
            100                 105                 110


Asn Ser Ser Val Pro Asp Leu Glu His Cys His Thr 
        115                 120


<210>  8552
<211>  568
<212>  DNA
<213>  Homo sapiens

<400>  8552
agttcttgga ttgagggtca gtttcctgag gaaggaactc aaagcaatgc aagaatggac     60

taatacgtct actgaaggac atcttggttg gtcccagatt ttggcaatta tgaaaaatct    120

gctatagatg tatgcaggtt ttctgtggac gtacgttttc cactcctgct ggccagacaa    180

cacatctaca gggtgcagat gacctatggg cagccacact gtgatgcctg tgtgagggcc    240

taaacttcag ggaggaagaa agtgaggtca gatcctgagg gagcacttgc tctcctgcag    300

caggcatggg ggagcacctg actgctgagg atggcttcgg aacatttgtg tgaagaggga    360

taacagatgc tgcatgccag agggatggtg gccataggcc gcaagattcg gttcttctgg    420

ccgcagaaga ccctgacttc acctttcagg cctctgtttc cttatcaacg aaataagagc    480

atgtgattaa ttctgcaggt gcttccagct tggacttttt tgcaaatatt ttcattcaac    540

tcactttaga aacctgcagg gagtctct                                       568


<210>  8553
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  8553

Met Gln Val Phe Cys Gly Arg Thr Phe Ser Thr Pro Ala Gly Gln Thr 
1               5                   10                  15


Thr His Leu Gln Gly Ala Asp Asp Leu Trp Ala Ala Thr Leu 
            20                  25                  30


<210>  8554
<211>  1469
<212>  DNA
<213>  Homo sapiens

<400>  8554
gtgggtagag gtgatgcagt gctgaagacc tgggcccctg ctcagtgcct ttgctctaga     60

atgggtccag cttggctttg gctactggga acagggatcc tggcctctgt ccactgtcag    120

ccccttcttg cccatggaga taaaagtctg caggggcctc aaccccccag gcatcagctc    180

tcagagccag cccccgccta ccacagaatc acacccacca ttaccaattt tgctttgcgt    240

ttgtataaag agctggcagc agacgccccc ggaaacatct tcttctcgcc agtgagcatc    300

tccaccaccc tggccctgct ctctcttggg gcccaagcta acacctcagc tctgatcctg    360

gagggcctgg gattcaacct cacagaaacc cctgaagccg acatccacca gggcttccgg    420

agcctcctcc acacccttgc cctgcccagc cccaaactcg aactaaaagt aggaaactcc    480

ctgttcctag acaagcgact aaagcctcgg cagcactatt tggacagcat caaggagctt    540

tatggagctt ttgctttttc tgccaacttc acagattctg ttacaactgg gaggcagatt    600

aatgactatt tgagaaggca aacatacggg caagtcgtgg actgcctccc ggagttcagc    660

caggacacgt tcatggttct tgccaattac atcttcttca aagccaagtg gaagcaccct    720

ttcagtcgct accagaccca gaagcaggaa agtttctttg tggatgagag gacttctctc    780

caggtcccca tgatgcacca aaaggaaatg cacagattcc tctatgacca ggatttggct    840

tgcaccgtcc tccagataga atacagagga aatgccttgg cgctgctggt cctccctgac    900

ccggggaaaa tgaagcaggt ggaggctgct ctgcagccac agaccctgag aaaatggggc    960

caattgctcc tgcccagtct gttggatttg cacttgccaa ggttttcaat ttctggaaca   1020

tataacctgg aagacatact tccccaaatt ggtctcacca acatactcaa cttagaagct   1080

gacttctcag gagtcactgg gcagctcaac aaaaccatct ccaaggtgtc acacaaggcg   1140

atggtggaca tgagtgagaa ggggaccgag gccggggctg cttcaggcct cctctcccag   1200

cccccatctc tgaacaccat gtcagaccca catgcccact tcaacaggcc tttcctcttg   1260

ctcctttggg aggtcaccac ccagagctta ctcttcctgg gaaaagttgt caacccagtt   1320

gcagggtaac catggtggga ggccaggagt tatcttatct catcctggac caaacagata   1380

ggccagaacc agcctgcatc ctggggctgc tatgtggttc agttaatcag tgtgccaaga   1440

ttctaataaa gttgaccttg ggttctgtg                                     1469


<210>  8555
<211>  422
<212>  PRT
<213>  Homo sapiens

<400>  8555

Met Gly Pro Ala Trp Leu Trp Leu Leu Gly Thr Gly Ile Leu Ala Ser 
1               5                   10                  15


Val His Cys Gln Pro Leu Leu Ala His Gly Asp Lys Ser Leu Gln Gly 
            20                  25                  30


Pro Gln Pro Pro Arg His Gln Leu Ser Glu Pro Ala Pro Ala Tyr His 
        35                  40                  45


Arg Ile Thr Pro Thr Ile Thr Asn Phe Ala Leu Arg Leu Tyr Lys Glu 
    50                  55                  60


Leu Ala Ala Asp Ala Pro Gly Asn Ile Phe Phe Ser Pro Val Ser Ile 
65                  70                  75                  80


Ser Thr Thr Leu Ala Leu Leu Ser Leu Gly Ala Gln Ala Asn Thr Ser 
                85                  90                  95


Ala Leu Ile Leu Glu Gly Leu Gly Phe Asn Leu Thr Glu Thr Pro Glu 
            100                 105                 110


Ala Asp Ile His Gln Gly Phe Arg Ser Leu Leu His Thr Leu Ala Leu 
        115                 120                 125


Pro Ser Pro Lys Leu Glu Leu Lys Val Gly Asn Ser Leu Phe Leu Asp 
    130                 135                 140


Lys Arg Leu Lys Pro Arg Gln His Tyr Leu Asp Ser Ile Lys Glu Leu 
145                 150                 155                 160


Tyr Gly Ala Phe Ala Phe Ser Ala Asn Phe Thr Asp Ser Val Thr Thr 
                165                 170                 175


Gly Arg Gln Ile Asn Asp Tyr Leu Arg Arg Gln Thr Tyr Gly Gln Val 
            180                 185                 190


Val Asp Cys Leu Pro Glu Phe Ser Gln Asp Thr Phe Met Val Leu Ala 
        195                 200                 205


Asn Tyr Ile Phe Phe Lys Ala Lys Trp Lys His Pro Phe Ser Arg Tyr 
    210                 215                 220


Gln Thr Gln Lys Gln Glu Ser Phe Phe Val Asp Glu Arg Thr Ser Leu 
225                 230                 235                 240


Gln Val Pro Met Met His Gln Lys Glu Met His Arg Phe Leu Tyr Asp 
                245                 250                 255


Gln Asp Leu Ala Cys Thr Val Leu Gln Ile Glu Tyr Arg Gly Asn Ala 
            260                 265                 270


Leu Ala Leu Leu Val Leu Pro Asp Pro Gly Lys Met Lys Gln Val Glu 
        275                 280                 285


Ala Ala Leu Gln Pro Gln Thr Leu Arg Lys Trp Gly Gln Leu Leu Leu 
    290                 295                 300


Pro Ser Leu Leu Asp Leu His Leu Pro Arg Phe Ser Ile Ser Gly Thr 
305                 310                 315                 320


Tyr Asn Leu Glu Asp Ile Leu Pro Gln Ile Gly Leu Thr Asn Ile Leu 
                325                 330                 335


Asn Leu Glu Ala Asp Phe Ser Gly Val Thr Gly Gln Leu Asn Lys Thr 
            340                 345                 350


Ile Ser Lys Val Ser His Lys Ala Met Val Asp Met Ser Glu Lys Gly 
        355                 360                 365


Thr Glu Ala Gly Ala Ala Ser Gly Leu Leu Ser Gln Pro Pro Ser Leu 
    370                 375                 380


Asn Thr Met Ser Asp Pro His Ala His Phe Asn Arg Pro Phe Leu Leu 
385                 390                 395                 400


Leu Leu Trp Glu Val Thr Thr Gln Ser Leu Leu Phe Leu Gly Lys Val 
                405                 410                 415


Val Asn Pro Val Ala Gly 
            420


<210>  8556
<211>  1513
<212>  DNA
<213>  Homo sapiens

<400>  8556
aagcaagtgt cagggctcac caaccatgca aggacagggc aggagaagag gaacctgcaa     60

aggctggttt tggagacccc gagtcagaac atcttcttct cccctgtgag tgtctccact    120

tccctggcca tgctctccct tggggcccac tcagtcacca agacccagat tctccagggc    180

ctgggcttca acctcacaca cacaccagag tctgccatcc accagggctt ccagcacctg    240

gttcactcac tgactgttcc cagcaaagac ctgaccttga agatgggaag tgccctcttc    300

gtcaagaagg agctgcagct gcaggcaaat ttcttgggca atgtcaagag gctgtatgaa    360

gcagaagtct tttctacaga tttctccaac ccctccattg cccaggcgag gatcaacagc    420

catgtgaaaa agaagaccca agggaaggtt gtagacataa tccaaggcct tgaccttctg    480

acggccatgg ttctggtgaa ccacattttc tttaaagcca agtgggagaa gccctttcac    540

cctgaatata caagaaagaa cttcccattc ctggtgggcg agcaggtcac tgtgcatgtc    600

cccatgatgc accagaaaga gcagttcgct tttggggtgg atacagagct gaactgcttt    660

gtgctgcaga tggattacaa gggagatgcc gtggccttct ttgtcctccc tagcaagggc    720

aagatgaggc aactggaaca ggccttgtca gccagaacac tgagaaagtg gagccactca    780

ctccagaaaa ggtggataga ggtgttcatc cccagatttt ccatttctgc ctcctacaat    840

ctggaaacca tcctcccgaa gatgggcatc caaaatgtct ttgacaaaaa tgctgatttt    900

tctggaattg caaagagaga ctccctgcag gtttctaaag caacccacaa ggctgtgctg    960

gatgtcagtg aagagggcac tgaggccaca gcagctacca ccaccaagtt catagtccga   1020

tcgaaggatg gcccctctta cttcactgtc tccttcaata ggaccttcct gatgatgatt   1080

acaaataaag ccacagacgg tattctcttt ctagggaaag tggaaaatcc cactaaatcc   1140

taggtgggaa atggcctgtt aactgatggc acattgctaa tgcacaagaa ataacaaacc   1200

acatccctct ttctgttctg agggtgcatt tgaccccagt ggagctggat tcgctggcag   1260

ggatgccact tccaaggctc aatcaccaaa ccatcaacag ggaccccagt cacaagccaa   1320

cacccattaa ccccagtcag tgcccttttc cacaaattct cccaggtaac tagcttcatg   1380

ggatgttgct gggttaccat atttccattc cttggggctc ccaggaatgg aaatacgcca   1440

acccaggtta ggcacctcta ttgcagaatt acaataacac attcaataaa actaaaatat   1500

gaattcatct gtc                                                      1513


<210>  8557
<211>  337
<212>  PRT
<213>  Homo sapiens

<400>  8557

Met Leu Ser Leu Gly Ala His Ser Val Thr Lys Thr Gln Ile Leu Gln 
1               5                   10                  15


Gly Leu Gly Phe Asn Leu Thr His Thr Pro Glu Ser Ala Ile His Gln 
            20                  25                  30


Gly Phe Gln His Leu Val His Ser Leu Thr Val Pro Ser Lys Asp Leu 
        35                  40                  45


Thr Leu Lys Met Gly Ser Ala Leu Phe Val Lys Lys Glu Leu Gln Leu 
    50                  55                  60


Gln Ala Asn Phe Leu Gly Asn Val Lys Arg Leu Tyr Glu Ala Glu Val 
65                  70                  75                  80


Phe Ser Thr Asp Phe Ser Asn Pro Ser Ile Ala Gln Ala Arg Ile Asn 
                85                  90                  95


Ser His Val Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile Ile Gln 
            100                 105                 110


Gly Leu Asp Leu Leu Thr Ala Met Val Leu Val Asn His Ile Phe Phe 
        115                 120                 125


Lys Ala Lys Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg Lys Asn 
    130                 135                 140


Phe Pro Phe Leu Val Gly Glu Gln Val Thr Val His Val Pro Met Met 
145                 150                 155                 160


His Gln Lys Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu Asn Cys 
                165                 170                 175


Phe Val Leu Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe Phe Val 
            180                 185                 190


Leu Pro Ser Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu Ser Ala 
        195                 200                 205


Arg Thr Leu Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp Ile Glu 
    210                 215                 220


Val Phe Ile Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu Glu Thr 
225                 230                 235                 240


Ile Leu Pro Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn Ala Asp 
                245                 250                 255


Phe Ser Gly Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys Ala Thr 
            260                 265                 270


His Lys Ala Val Leu Asp Val Ser Glu Glu Gly Thr Glu Ala Thr Ala 
        275                 280                 285


Ala Thr Thr Thr Lys Phe Ile Val Arg Ser Lys Asp Gly Pro Ser Tyr 
    290                 295                 300


Phe Thr Val Ser Phe Asn Arg Thr Phe Leu Met Met Ile Thr Asn Lys 
305                 310                 315                 320


Ala Thr Asp Gly Ile Leu Phe Leu Gly Lys Val Glu Asn Pro Thr Lys 
                325                 330                 335


Ser 



<210>  8558
<211>  1416
<212>  DNA
<213>  Homo sapiens

<400>  8558
gctacaacca agtaagcaag tgtcagggct caccaaccat gcaaggacag ggcaggagaa     60

gaggaacctg caaagacata ttttgttcca aaatggcatc ttacctttat ggagtactct    120

ttgctgttgg cctctgtgct ccaatctact gtgtgtcccc ggccaatgcc cccagtgcat    180

acccccgccc ttcctccaca aagagcaccc ctgcctcaca ggtgtattcc ctcaacaccg    240

actttgcctt ccgcctatac cgcaggctgg ttttggagac cccgagtcag aacatcttct    300

tctcccctgc gaggatcaac agccatgtga aaaagaagac ccaagggaag gttgtagaca    360

taatccaagg ccttgacctt ctgacggcca tggttctggt gaaccacatt ttctttaaag    420

ccaagtggga gaagcccttt caccctgaat atacaagaaa gaacttccca ttcctggtgg    480

gcgagcaggt cactgtgcat gtccccatga tgcaccagaa agagcagttc gcttttgggg    540

tggatacaga gctgaactgc tttgtgctgc agatggatta caagggagat gccgtggcct    600

tctttgtcct ccctagcaag ggcaagatga ggcaactgga acaggccttg tcagccagaa    660

cactgagaaa gtggagccac tcactccaga aaaggtggat agaggtgttc atccccagat    720

tttccatttc tgcctcctac aatctggaaa ccatcctccc gaagatgggc atccaaaatg    780

tctttgacaa aaatgctgat ttttctggaa ttgcaaagag agactccctg caggtttcta    840

aagcaaccca caaggctgtg ctggatgtca gtgaagaggg cactgaggcc acagcagcta    900

ccaccaccaa gttcatagtc cgatcgaagg atggcccctc ttacttcact gtctccttca    960

ataggacctt cctgatgatg attacaaata aagccacaga cggtattctc tttctaggga   1020

aagtggaaaa tcccactaaa tcctaggtgg gaaatggcct gttaactgat ggcacattgc   1080

taatgcacaa gaaataacaa accacatccc tctttctgtt ctgagggtgc atttgacccc   1140

agtggagctg gattcgctgg cagggatgcc acttccaagg ctcaatcacc aaaccatcaa   1200

cagggacccc agtcacaagc caacacccat taaccccagt cagtgccctt ttccacaaat   1260

tctcccaggt aactagcttc atgggatgtt gctgggttac catatttcca ttccttgggg   1320

ctcccaggaa tggaaatacg ccaacccagg ttaggcacct ctattgcaga attacaataa   1380

cacattcaat aaaactaaaa tatgaattca tctgtc                             1416


<210>  8559
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  8559

Met Gln Gly Gln Gly Arg Arg Arg Gly Thr Cys Lys Asp Ile Phe Cys 
1               5                   10                  15


Ser Lys Met Ala Ser Tyr Leu Tyr Gly Val Leu Phe Ala Val Gly Leu 
            20                  25                  30


Cys Ala Pro Ile Tyr Cys Val Ser Pro Ala Asn Ala Pro Ser Ala Tyr 
        35                  40                  45


Pro Arg Pro Ser Ser Thr Lys Ser Thr Pro Ala Ser Gln Val Tyr Ser 
    50                  55                  60


Leu Asn Thr Asp Phe Ala Phe Arg Leu Tyr Arg Arg Leu Val Leu Glu 
65                  70                  75                  80


Thr Pro Ser Gln Asn Ile Phe Phe Ser Pro Ala Arg Ile Asn Ser His 
                85                  90                  95


Val Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile Ile Gln Gly Leu 
            100                 105                 110


Asp Leu Leu Thr Ala Met Val Leu Val Asn His Ile Phe Phe Lys Ala 
        115                 120                 125


Lys Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg Lys Asn Phe Pro 
    130                 135                 140


Phe Leu Val Gly Glu Gln Val Thr Val His Val Pro Met Met His Gln 
145                 150                 155                 160


Lys Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu Asn Cys Phe Val 
                165                 170                 175


Leu Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe Phe Val Leu Pro 
            180                 185                 190


Ser Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu Ser Ala Arg Thr 
        195                 200                 205


Leu Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp Ile Glu Val Phe 
    210                 215                 220


Ile Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu Glu Thr Ile Leu 
225                 230                 235                 240


Pro Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn Ala Asp Phe Ser 
                245                 250                 255


Gly Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys Ala Thr His Lys 
            260                 265                 270


Ala Val Leu Asp Val Ser Glu Glu Gly Thr Glu Ala Thr Ala Ala Thr 
        275                 280                 285


Thr Thr Lys Phe Ile Val Arg Ser Lys Asp Gly Pro Ser Tyr Phe Thr 
    290                 295                 300


Val Ser Phe Asn Arg Thr Phe Leu Met Met Ile Thr Asn Lys Ala Thr 
305                 310                 315                 320


Asp Gly Ile Leu Phe Leu Gly Lys Val Glu Asn Pro Thr Lys Ser 
                325                 330                 335


<210>  8560
<211>  1455
<212>  DNA
<213>  Homo sapiens

<400>  8560
ggagggagag gagagattaa agtgaggaga gagctacaac caagtaagca agtgtcaggg     60

ctcaccaacc atgcaaggac agggcaggag aagaggaacc tgcaaagtcc atgaagcaga    120

aacatcaaaa agcatgggat ttggaatttg agacctgact ttgaagccca cacagaacac    180

agacaagtca accatgctat ttgggcaaag acctgacctt gaagatggga agtgccctct    240

tcgtcaagaa ggagctgcag ctgcaggcaa atttcttggg caatgtcaag aggctgtatg    300

aagcagaagt cttttctaca gatttctcca acccctccat tgcccaggcg aggatcaaca    360

gccatgtgaa aaagaagacc caagggaagg ttgtagacat aatccaaggc cttgaccttc    420

tgacggccat ggttctggtg aaccacattt tctttaaagc caagtgggag aagccctttc    480

accctgaata tacaagaaag aacttcccat tcctggtggg cgagcaggtc actgtgcatg    540

tccccatgat gcaccagaaa gagcagttcg cttttggggt ggatacagag ctgaactgct    600

ttgtgctgca gatggattac aagggagatg ccgtggcctt ctttgtcctc cctagcaagg    660

gcaagatgag gcaactggaa caggccttgt cagccagaac actgagaaag tggagccact    720

cactccagaa aaggtggata gaggtgttca tccccagatt ttccatttct gcctcctaca    780

atctggaaac catcctcccg aagatgggca tccaaaatgt ctttgacaaa aatgctgatt    840

tttctggaat tgcaaagaga gactccctgc aggtttctaa agcaacccac aaggctgtgc    900

tggatgtcag tgaagagggc actgaggcca cagcagctac caccaccaag ttcatagtcc    960

gatcgaagga tggcccctct tacttcactg tctccttcaa taggaccttc ctgatgatga   1020

ttacaaataa agccacagac ggtattctct ttctagggaa agtggaaaat cccactaaat   1080

cctaggtggg aaatggcctg ttaactgatg gcacattgct aatgcacaag aaataacaaa   1140

ccacatccct ctttctgttc tgagggtgca tttgacccca gtggagctgg attcgctggc   1200

agggatgcca cttccaaggc tcaatcacca aaccatcaac agggacccca gtcacaagcc   1260

aacacccatt aaccccagtc agtgcccttt tccacaaatt ctcccaggta actagcttca   1320

tgggatgttg ctgggttacc atatttccat tccttggggc tcccaggaat ggaaatacgc   1380

caacccaggt taggcacctc tattgcagaa ttacaataac acattcaata aaactaaaat   1440

atgaattcat ctgtc                                                    1455


<210>  8561
<211>  286
<212>  PRT
<213>  Homo sapiens

<400>  8561

Met Gly Ser Ala Leu Phe Val Lys Lys Glu Leu Gln Leu Gln Ala Asn 
1               5                   10                  15


Phe Leu Gly Asn Val Lys Arg Leu Tyr Glu Ala Glu Val Phe Ser Thr 
            20                  25                  30


Asp Phe Ser Asn Pro Ser Ile Ala Gln Ala Arg Ile Asn Ser His Val 
        35                  40                  45


Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile Ile Gln Gly Leu Asp 
    50                  55                  60


Leu Leu Thr Ala Met Val Leu Val Asn His Ile Phe Phe Lys Ala Lys 
65                  70                  75                  80


Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg Lys Asn Phe Pro Phe 
                85                  90                  95


Leu Val Gly Glu Gln Val Thr Val His Val Pro Met Met His Gln Lys 
            100                 105                 110


Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu Asn Cys Phe Val Leu 
        115                 120                 125


Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe Phe Val Leu Pro Ser 
    130                 135                 140


Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu Ser Ala Arg Thr Leu 
145                 150                 155                 160


Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp Ile Glu Val Phe Ile 
                165                 170                 175


Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu Glu Thr Ile Leu Pro 
            180                 185                 190


Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn Ala Asp Phe Ser Gly 
        195                 200                 205


Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys Ala Thr His Lys Ala 
    210                 215                 220


Val Leu Asp Val Ser Glu Glu Gly Thr Glu Ala Thr Ala Ala Thr Thr 
225                 230                 235                 240


Thr Lys Phe Ile Val Arg Ser Lys Asp Gly Pro Ser Tyr Phe Thr Val 
                245                 250                 255


Ser Phe Asn Arg Thr Phe Leu Met Met Ile Thr Asn Lys Ala Thr Asp 
            260                 265                 270


Gly Ile Leu Phe Leu Gly Lys Val Glu Asn Pro Thr Lys Ser 
        275                 280                 285


<210>  8562
<211>  1752
<212>  DNA
<213>  Homo sapiens

<400>  8562
agctggaggg agaggagaga ttaaagtgag gagagagcta caaccaagta agcaagtgtc     60

agggctcacc aaccatgcaa ggacagggca ggagaagagg aacctgcaaa gacatatttt    120

gttccaaaat ggcatcttac ctttatggag tactctttgc tgttggcctc tgtgctccaa    180

tctactgtgt gtccccggcc aatgccccca gtgcataccc ccgcccttcc tccacaaaga    240

gcacccctgc ctcacaggtg tattccctca acaccgactt tgccttccgc ctataccgca    300

ggctggtttt ggagaccccg agtcagaaca tcttcttctc ccctgtgagt gtctccactt    360

ccctggccat gctctccctt ggggcccact cagtcaccaa gacccagatt ctccagggcc    420

tgggcttcaa cctcacacac acaccagagt ctgccatcca ccagggcttc cagcacctgg    480

ttcactcact gactgttccc agcaaagacc tgaccttgaa gatgggaagt gccctcttcg    540

tcaagaagga gctgcagctg caggcaaatt tcttgggcaa tgtcaagagg ctgtatgaag    600

cagaagtctt ttctacagat ttctccaacc cctccattgc ccaggcgagg atcaacagcc    660

atgtgaaaaa gaagacccaa gggaaggttg tagacataat ccaaggcctt gaccttctga    720

cggccatggt tctggtgaac cacattttct ttaaagccaa gtgggagaag ccctttcacc    780

ctgaatatac aagaaagaac ttcccattcc tggtgggcga gcaggtcact gtgcatgtcc    840

ccatgatgca ccagaaagag cagttcgctt ttggggtgga tacagagctg aactgctttg    900

tgctgcagat ggattacaag ggagatgccg tggccttctt tgtcctccct agcaagggca    960

agatgaggca actggaacag gccttgtcag ccagaacact gagaaagtgg agccactcac   1020

tccagaaaag gtggatagag gtgttcatcc ccagattttc catttctgcc tcctacaatc   1080

tggaaaccat cctcccgaag atgggcatcc aaaatgtctt tgacaaaaat gctgattttt   1140

ctggaattgc aaagagagac tccctgcagg tttctaaagc aacccacaag gctgtgctgg   1200

atgtcagtga agagggcact gaggccacag cagctaccac caccaagttc atagtccgat   1260

cgaaggatgg cccctcttac ttcactgtct ccttcaatag gaccttcctg atgatgatta   1320

caaataaagc cacagacggt attctctttc tagggaaagt ggaaaatccc actaaatcct   1380

aggtgggaaa tggcctgtta actgatggca cattgctaat gcacaagaaa taacaaacca   1440

catccctctt tctgttctga gggtgcattt gaccccagtg gagctggatt cgctggcagg   1500

gatgccactt ccaaggctca atcaccaaac catcaacagg gaccccagtc acaagccaac   1560

acccattaac cccagtcagt gcccttttcc acaaattctc ccaggtaact agcttcatgg   1620

gatgttgctg ggttaccata tttccattcc ttggggctcc caggaatgga aatacgccaa   1680

cccaggttag gcacctctat tgcagaatta caataacaca ttcaataaaa ctaaaatatg   1740

aattcatctg tc                                                       1752


<210>  8563
<211>  435
<212>  PRT
<213>  Homo sapiens

<400>  8563

Met Gln Gly Gln Gly Arg Arg Arg Gly Thr Cys Lys Asp Ile Phe Cys 
1               5                   10                  15


Ser Lys Met Ala Ser Tyr Leu Tyr Gly Val Leu Phe Ala Val Gly Leu 
            20                  25                  30


Cys Ala Pro Ile Tyr Cys Val Ser Pro Ala Asn Ala Pro Ser Ala Tyr 
        35                  40                  45


Pro Arg Pro Ser Ser Thr Lys Ser Thr Pro Ala Ser Gln Val Tyr Ser 
    50                  55                  60


Leu Asn Thr Asp Phe Ala Phe Arg Leu Tyr Arg Arg Leu Val Leu Glu 
65                  70                  75                  80


Thr Pro Ser Gln Asn Ile Phe Phe Ser Pro Val Ser Val Ser Thr Ser 
                85                  90                  95


Leu Ala Met Leu Ser Leu Gly Ala His Ser Val Thr Lys Thr Gln Ile 
            100                 105                 110


Leu Gln Gly Leu Gly Phe Asn Leu Thr His Thr Pro Glu Ser Ala Ile 
        115                 120                 125


His Gln Gly Phe Gln His Leu Val His Ser Leu Thr Val Pro Ser Lys 
    130                 135                 140


Asp Leu Thr Leu Lys Met Gly Ser Ala Leu Phe Val Lys Lys Glu Leu 
145                 150                 155                 160


Gln Leu Gln Ala Asn Phe Leu Gly Asn Val Lys Arg Leu Tyr Glu Ala 
                165                 170                 175


Glu Val Phe Ser Thr Asp Phe Ser Asn Pro Ser Ile Ala Gln Ala Arg 
            180                 185                 190


Ile Asn Ser His Val Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile 
        195                 200                 205


Ile Gln Gly Leu Asp Leu Leu Thr Ala Met Val Leu Val Asn His Ile 
    210                 215                 220


Phe Phe Lys Ala Lys Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg 
225                 230                 235                 240


Lys Asn Phe Pro Phe Leu Val Gly Glu Gln Val Thr Val His Val Pro 
                245                 250                 255


Met Met His Gln Lys Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu 
            260                 265                 270


Asn Cys Phe Val Leu Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe 
        275                 280                 285


Phe Val Leu Pro Ser Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu 
    290                 295                 300


Ser Ala Arg Thr Leu Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp 
305                 310                 315                 320


Ile Glu Val Phe Ile Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu 
                325                 330                 335


Glu Thr Ile Leu Pro Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn 
            340                 345                 350


Ala Asp Phe Ser Gly Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys 
        355                 360                 365


Ala Thr His Lys Ala Val Leu Asp Val Ser Glu Glu Gly Thr Glu Ala 
    370                 375                 380


Thr Ala Ala Thr Thr Thr Lys Phe Ile Val Arg Ser Lys Asp Gly Pro 
385                 390                 395                 400


Ser Tyr Phe Thr Val Ser Phe Asn Arg Thr Phe Leu Met Met Ile Thr 
                405                 410                 415


Asn Lys Ala Thr Asp Gly Ile Leu Phe Leu Gly Lys Val Glu Asn Pro 
            420                 425                 430


Thr Lys Ser 
        435


<210>  8564
<211>  1346
<212>  DNA
<213>  Homo sapiens

<400>  8564
atcatttgca tgtctagctg gagaataaaa ataatatatc atttgcatgt cttagtaatg     60

aagtcatggg tgtcgtggca tgagatcagc tggagggaga ggagagatta aagtgaggag    120

agagctacaa ccaagtaagc aagtgtcagg gctcaccaac catgcaagga cagggcagga    180

gaagaggaac ctgcaaagac atattttgtt ccaaaatggc atcttacctt tatggagtac    240

tctttgctgt tggcctctgt gctccaatct actgtgtgtc cccggccaat gcccccagtg    300

catacccccg cccttcctcc acaaagagca cccctgcctc acaggtgtat tccctcaaca    360

ccgactttgc cttccgccta taccgcaggc tggttttgga gaccccgagt cagaacatct    420

tcttctcccc tgtgagtgtc tccacttccc tggccatgct ctcccttggg gcccactcag    480

tcaccaagac ccagattctc cagggcctgg gcttcaacct cacacacaca ccagagtctg    540

ccatccacca gggcttccag cacctggttc actcactgac tgttcccagc aaagacctga    600

ccttgaagat gggaagtgcc ctcttcgtca agaaggagct gcagctgcag gcaaatttct    660

tgggcaatgt caagaggctg tatgaagcag aagtcttttc tacagatttc tccaacccct    720

ccattgccca ggcgaggatc aacagccatg tgaaaaagaa gacccaaggg aaggttgtag    780

acataatcca aggccttgac cttctgacgg ccatggttct ggtgaaccac attttcttta    840

aagccaagtg ggagaagccc tttcaccctg aatatacaag aaagaacttc ccattcctgg    900

tgggcgagca ggtcactgtg catgtcccca tgatgcacca gaaagagcag ttcgcttttg    960

gggtggatac agagctgaac tgctttgtgc tgcagatgga ttacaaggga gatgccgtgg   1020

ccttctttgt cctccctagc aagggcaaga tgaggcaact ggaacaggcc ttgtcagcca   1080

gaacactgag aaagtggagc cactcactcc agaaaaggtg gatagaggtg ttcatcccca   1140

gattttccat ttctgcctcc tacaatctgg aaaccatcct cccgaagatg ggcatccaaa   1200

atgtctttga caaaaatgct gatttttctg gaattgcaaa gagagactcc ctgcaggttt   1260

ctaaagtgag ttgaatgaaa atatttgcaa aaaagtccaa gctggaagca cctgcagaat   1320

taatcacatg ctcttatttc gttgat                                        1346


<210>  8565
<211>  370
<212>  PRT
<213>  Homo sapiens

<400>  8565

Met Gln Gly Gln Gly Arg Arg Arg Gly Thr Cys Lys Asp Ile Phe Cys 
1               5                   10                  15


Ser Lys Met Ala Ser Tyr Leu Tyr Gly Val Leu Phe Ala Val Gly Leu 
            20                  25                  30


Cys Ala Pro Ile Tyr Cys Val Ser Pro Ala Asn Ala Pro Ser Ala Tyr 
        35                  40                  45


Pro Arg Pro Ser Ser Thr Lys Ser Thr Pro Ala Ser Gln Val Tyr Ser 
    50                  55                  60


Leu Asn Thr Asp Phe Ala Phe Arg Leu Tyr Arg Arg Leu Val Leu Glu 
65                  70                  75                  80


Thr Pro Ser Gln Asn Ile Phe Phe Ser Pro Val Ser Val Ser Thr Ser 
                85                  90                  95


Leu Ala Met Leu Ser Leu Gly Ala His Ser Val Thr Lys Thr Gln Ile 
            100                 105                 110


Leu Gln Gly Leu Gly Phe Asn Leu Thr His Thr Pro Glu Ser Ala Ile 
        115                 120                 125


His Gln Gly Phe Gln His Leu Val His Ser Leu Thr Val Pro Ser Lys 
    130                 135                 140


Asp Leu Thr Leu Lys Met Gly Ser Ala Leu Phe Val Lys Lys Glu Leu 
145                 150                 155                 160


Gln Leu Gln Ala Asn Phe Leu Gly Asn Val Lys Arg Leu Tyr Glu Ala 
                165                 170                 175


Glu Val Phe Ser Thr Asp Phe Ser Asn Pro Ser Ile Ala Gln Ala Arg 
            180                 185                 190


Ile Asn Ser His Val Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile 
        195                 200                 205


Ile Gln Gly Leu Asp Leu Leu Thr Ala Met Val Leu Val Asn His Ile 
    210                 215                 220


Phe Phe Lys Ala Lys Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg 
225                 230                 235                 240


Lys Asn Phe Pro Phe Leu Val Gly Glu Gln Val Thr Val His Val Pro 
                245                 250                 255


Met Met His Gln Lys Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu 
            260                 265                 270


Asn Cys Phe Val Leu Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe 
        275                 280                 285


Phe Val Leu Pro Ser Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu 
    290                 295                 300


Ser Ala Arg Thr Leu Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp 
305                 310                 315                 320


Ile Glu Val Phe Ile Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu 
                325                 330                 335


Glu Thr Ile Leu Pro Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn 
            340                 345                 350


Ala Asp Phe Ser Gly Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys 
        355                 360                 365


Val Ser 
    370


<210>  8566
<211>  1156
<212>  DNA
<213>  Homo sapiens

<400>  8566
atcatttgca tgtctagctg gagaataaaa ataatatatc atttgcatgt cttagtaatg     60

aagtcatggg tgtcgtggca tgagatcagc tggagggaga ggagagatta aagtgaggag    120

agagctacaa ccaagtaagc aagtgtcagg gctcaccaac catgcaagga cagggcagga    180

gaagaggaac ctgcaaaggc tggttttgga gaccccgagt cagaacatct tcttctcccc    240

tgtgagtgtc tccacttccc tggccatgct ctcccttggg gcccactcag tcaccaagac    300

ccagattctc cagggcctgg gcttcaacct cacacacaca ccagagtctg ccatccacca    360

gggcttccag cacctggttc actcactgac tgttcccagc aaagacctga ccttgaagat    420

gggaagtgcc ctcttcgtca agaaggagct gcagctgcag gcaaatttct tgggcaatgt    480

caagaggctg tatgaagcag aagtcttttc tacagatttc tccaacccct ccattgccca    540

ggcgaggatc aacagccatg tgaaaaagaa gacccaaggg aaggttgtag acataatcca    600

aggccttgac cttctgacgg ccatggttct ggtgaaccac attttcttta aagccaagtg    660

ggagaagccc tttcaccctg aatatacaag aaagaacttc ccattcctgg tgggcgagca    720

ggtcactgtg catgtcccca tgatgcacca gaaagagcag ttcgcttttg gggtggatac    780

agagctgaac tgctttgtgc tgcagatgga ttacaaggga gatgccgtgg ccttctttgt    840

cctccctagc aagggcaaga tgaggcaact ggaacaggcc ttgtcagcca gaacactgag    900

aaagtggagc cactcactcc agaaaaggtg gatagaggtg ttcatcccca gattttccat    960

ttctgcctcc tacaatctgg aaaccatcct cccgaagatg ggcatccaaa atgtctttga   1020

caaaaatgct gatttttctg gaattgcaaa gagagactcc ctgcaggttt ctaaagtgag   1080

ttgaatgaaa atatttgcaa aaaagtccaa gctggaagca cctgcagaat taatcacatg   1140

ctcttatttc gttgat                                                   1156


<210>  8567
<211>  334
<212>  PRT
<213>  Homo sapiens

<400>  8567

Met Arg Ser Ala Gly Gly Arg Gly Glu Ile Lys Val Arg Arg Glu Leu 
1               5                   10                  15


Gln Pro Ser Lys Gln Val Ser Gly Leu Thr Asn His Ala Arg Thr Gly 
            20                  25                  30


Gln Glu Lys Arg Asn Leu Gln Arg Leu Val Leu Glu Thr Pro Ser Gln 
        35                  40                  45


Asn Ile Phe Phe Ser Pro Val Ser Val Ser Thr Ser Leu Ala Met Leu 
    50                  55                  60


Ser Leu Gly Ala His Ser Val Thr Lys Thr Gln Ile Leu Gln Gly Leu 
65                  70                  75                  80


Gly Phe Asn Leu Thr His Thr Pro Glu Ser Ala Ile His Gln Gly Phe 
                85                  90                  95


Gln His Leu Val His Ser Leu Thr Val Pro Ser Lys Asp Leu Thr Leu 
            100                 105                 110


Lys Met Gly Ser Ala Leu Phe Val Lys Lys Glu Leu Gln Leu Gln Ala 
        115                 120                 125


Asn Phe Leu Gly Asn Val Lys Arg Leu Tyr Glu Ala Glu Val Phe Ser 
    130                 135                 140


Thr Asp Phe Ser Asn Pro Ser Ile Ala Gln Ala Arg Ile Asn Ser His 
145                 150                 155                 160


Val Lys Lys Lys Thr Gln Gly Lys Val Val Asp Ile Ile Gln Gly Leu 
                165                 170                 175


Asp Leu Leu Thr Ala Met Val Leu Val Asn His Ile Phe Phe Lys Ala 
            180                 185                 190


Lys Trp Glu Lys Pro Phe His Pro Glu Tyr Thr Arg Lys Asn Phe Pro 
        195                 200                 205


Phe Leu Val Gly Glu Gln Val Thr Val His Val Pro Met Met His Gln 
    210                 215                 220


Lys Glu Gln Phe Ala Phe Gly Val Asp Thr Glu Leu Asn Cys Phe Val 
225                 230                 235                 240


Leu Gln Met Asp Tyr Lys Gly Asp Ala Val Ala Phe Phe Val Leu Pro 
                245                 250                 255


Ser Lys Gly Lys Met Arg Gln Leu Glu Gln Ala Leu Ser Ala Arg Thr 
            260                 265                 270


Leu Arg Lys Trp Ser His Ser Leu Gln Lys Arg Trp Ile Glu Val Phe 
        275                 280                 285


Ile Pro Arg Phe Ser Ile Ser Ala Ser Tyr Asn Leu Glu Thr Ile Leu 
    290                 295                 300


Pro Lys Met Gly Ile Gln Asn Val Phe Asp Lys Asn Ala Asp Phe Ser 
305                 310                 315                 320


Gly Ile Ala Lys Arg Asp Ser Leu Gln Val Ser Lys Val Ser 
                325                 330


<210>  8568
<211>  908
<212>  DNA
<213>  Homo sapiens

<400>  8568
atagtatgag tatctccaat aaaccagaag tggagcagaa gcataagaat gtgtgaggca     60

ggcaagagat cctgtagcca gagtcctaag aggatcccag aaaggcctgg acatagcagg    120

agaggctcca tggaggagta tggacttggg agaaggctcc atcttgatgg gcccatgggg    180

atctactcct ggctggttgc tactccagca ggcttggttt tatgaatttg gggagaaatg    240

ggtctttact ttcaaggtgg ccctgaggcc ccaggaactg aggacctcag agctagagga    300

aaccctgaag agcttctctc tggggcaagg acagaaggtg gggtgaaggg taggaagagg    360

aagcacacag ccctccccac tctcaagtct tctcatcttt ccctggaaaa tctgattagg    420

tagttctgca tgggacctgg aaatttgcat tttaatgaga gcccaattac gcttgacata    480

ttttgttcca aaatggcatc ttacctttat ggagtactct ttgctgttgg cctctgtgct    540

ccaatctact gtgtgtcccc ggccaatgcc cccagtgcat acccccgccc ttcctccaca    600

aagagcaccc ctgcctcaca ggtgtattcc ctcaacaccg actttgcctt ccgcctatac    660

cgcaggctgg ttttggagac cccgagtcag aacatcttct tctcccctgt gagtgtctcc    720

acttccctgg ccatgctctc ccttggggcc cactcagtca ccaagaccca gattctccag    780

ggcctgggct tcaacctcac acacacacca gagtctgcca tccaccaggg cttccagcac    840

ctggttcact cactgactgt tcccagcaaa gacctgacct tgaagatggg aagtgccctc    900

ttcgtcaa                                                             908


<210>  8569
<211>  158
<212>  PRT
<213>  Homo sapiens

<400>  8569

Met Gly Pro Gly Asn Leu His Phe Asn Glu Ser Pro Ile Thr Leu Asp 
1               5                   10                  15


Ile Phe Cys Ser Lys Met Ala Ser Tyr Leu Tyr Gly Val Leu Phe Ala 
            20                  25                  30


Val Gly Leu Cys Ala Pro Ile Tyr Cys Val Ser Pro Ala Asn Ala Pro 
        35                  40                  45


Ser Ala Tyr Pro Arg Pro Ser Ser Thr Lys Ser Thr Pro Ala Ser Gln 
    50                  55                  60


Val Tyr Ser Leu Asn Thr Asp Phe Ala Phe Arg Leu Tyr Arg Arg Leu 
65                  70                  75                  80


Val Leu Glu Thr Pro Ser Gln Asn Ile Phe Phe Ser Pro Val Ser Val 
                85                  90                  95


Ser Thr Ser Leu Ala Met Leu Ser Leu Gly Ala His Ser Val Thr Lys 
            100                 105                 110


Thr Gln Ile Leu Gln Gly Leu Gly Phe Asn Leu Thr His Thr Pro Glu 
        115                 120                 125


Ser Ala Ile His Gln Gly Phe Gln His Leu Val His Ser Leu Thr Val 
    130                 135                 140


Pro Ser Lys Asp Leu Thr Leu Lys Met Gly Ser Ala Leu Phe 
145                 150                 155


<210>  8570
<211>  1497
<212>  DNA
<213>  Homo sapiens

<400>  8570
ggccttactc ttccaagagg ccatggaagt ataaataata aagcaagaaa ggcagatgca     60

tttggctggc tcagtggact tctgaatgta ctgtgagtat gagaccttcc cttccaaaag    120

atccggtgct tcttgtctat tccacacgaa gcttgcttca gatcgaggga ggatgtagca    180

ctgtccacag gtctactact caacaggata ttcttcaagg aaaatgaacc ccacactagg    240

cctggccatt tttctggctg ttctcctcac ggtgaaaggt cttctaaagc cgagcttctc    300

accaaggaat tataaagctt tgagcgaggt ccaaggatgg aagcaaagga tggcagccaa    360

ggagcttgca aggcagaaca tggacttagg ctttaagctg ctcaagaagc tggcctttta    420

caaccctggc aggaacatct tcctatcccc cttgagcatc tctacagctt tctccatgct    480

gtgcctgggt gcccaggaca gcaccctgga cgagatcaag caggggttca acttcagaaa    540

gatgccagaa aaagatcttc atgagggctt ccattacatc atccacgagc tgacccagaa    600

gacccaggac ctcaaactga gcattgggaa cacgctgttc attgaccaga ggctgcagcc    660

acagcgtaag tttttggaag atgccaagaa cttttacagt gccgaaacca tccttaccaa    720

ctttcagaat ttggaaatgg ctcagaagca gatcaatgac tttatcagtc aaaaaaccca    780

tgggaaaatt aacaacctga tcgagaatat agaccccggc actgtgatgc ttcttgcaaa    840

ttatattttc tttcgagcca ggtggaaaca tgagtttgat ccaaatgtaa ctaaagagga    900

agatttcttt ctggagaaaa acagttcagt caaggtgccc atgatgttcc gtagtggcat    960

ataccaagtt ggctatgacg ataagctctc ttgcaccatc ctggaaatac cctaccagaa   1020

aaatatcaca gccatcttca tccttcctga tgagggcaag ctgaagcact tggagaaggg   1080

attgcaggtg gacactttct ccagatggaa aacattactg tcacgcaggg tcgtagacgt   1140

gtctgtaccc agactccaca tgacgggcac cttcgacctg aagaagactc tctcctacat   1200

aggtgtctcc aaaatctttg aggaacatgg tgatctcacc aagatcgccc ctcatcgcag   1260

cctgaaagtg ggcgaggctg tgcacaaggc tgagctgaag atggatgaga ggggtacgga   1320

aggggccgct ggcaccggag cacagactct gcccatggag acaccactcg tcgtcaagat   1380

agacaaaccc tatctgctgc tgatttacag cgagaaaata ccttccgtgc tcttcctggg   1440

aaagattgtt aaccctattg gaaaataaag gagaattcct gcttgccaca gaccccg      1497


<210>  8571
<211>  414
<212>  PRT
<213>  Homo sapiens

<400>  8571

Met Asn Pro Thr Leu Gly Leu Ala Ile Phe Leu Ala Val Leu Leu Thr 
1               5                   10                  15


Val Lys Gly Leu Leu Lys Pro Ser Phe Ser Pro Arg Asn Tyr Lys Ala 
            20                  25                  30


Leu Ser Glu Val Gln Gly Trp Lys Gln Arg Met Ala Ala Lys Glu Leu 
        35                  40                  45


Ala Arg Gln Asn Met Asp Leu Gly Phe Lys Leu Leu Lys Lys Leu Ala 
    50                  55                  60


Phe Tyr Asn Pro Gly Arg Asn Ile Phe Leu Ser Pro Leu Ser Ile Ser 
65                  70                  75                  80


Thr Ala Phe Ser Met Leu Cys Leu Gly Ala Gln Asp Ser Thr Leu Asp 
                85                  90                  95


Glu Ile Lys Gln Gly Phe Asn Phe Arg Lys Met Pro Glu Lys Asp Leu 
            100                 105                 110


His Glu Gly Phe His Tyr Ile Ile His Glu Leu Thr Gln Lys Thr Gln 
        115                 120                 125


Asp Leu Lys Leu Ser Ile Gly Asn Thr Leu Phe Ile Asp Gln Arg Leu 
    130                 135                 140


Gln Pro Gln Arg Lys Phe Leu Glu Asp Ala Lys Asn Phe Tyr Ser Ala 
145                 150                 155                 160


Glu Thr Ile Leu Thr Asn Phe Gln Asn Leu Glu Met Ala Gln Lys Gln 
                165                 170                 175


Ile Asn Asp Phe Ile Ser Gln Lys Thr His Gly Lys Ile Asn Asn Leu 
            180                 185                 190


Ile Glu Asn Ile Asp Pro Gly Thr Val Met Leu Leu Ala Asn Tyr Ile 
        195                 200                 205


Phe Phe Arg Ala Arg Trp Lys His Glu Phe Asp Pro Asn Val Thr Lys 
    210                 215                 220


Glu Glu Asp Phe Phe Leu Glu Lys Asn Ser Ser Val Lys Val Pro Met 
225                 230                 235                 240


Met Phe Arg Ser Gly Ile Tyr Gln Val Gly Tyr Asp Asp Lys Leu Ser 
                245                 250                 255


Cys Thr Ile Leu Glu Ile Pro Tyr Gln Lys Asn Ile Thr Ala Ile Phe 
            260                 265                 270


Ile Leu Pro Asp Glu Gly Lys Leu Lys His Leu Glu Lys Gly Leu Gln 
        275                 280                 285


Val Asp Thr Phe Ser Arg Trp Lys Thr Leu Leu Ser Arg Arg Val Val 
    290                 295                 300


Asp Val Ser Val Pro Arg Leu His Met Thr Gly Thr Phe Asp Leu Lys 
305                 310                 315                 320


Lys Thr Leu Ser Tyr Ile Gly Val Ser Lys Ile Phe Glu Glu His Gly 
                325                 330                 335


Asp Leu Thr Lys Ile Ala Pro His Arg Ser Leu Lys Val Gly Glu Ala 
            340                 345                 350


Val His Lys Ala Glu Leu Lys Met Asp Glu Arg Gly Thr Glu Gly Ala 
        355                 360                 365


Ala Gly Thr Gly Ala Gln Thr Leu Pro Met Glu Thr Pro Leu Val Val 
    370                 375                 380


Lys Ile Asp Lys Pro Tyr Leu Leu Leu Ile Tyr Ser Glu Lys Ile Pro 
385                 390                 395                 400


Ser Val Leu Phe Leu Gly Lys Ile Val Asn Pro Ile Gly Lys 
                405                 410


<210>  8572
<211>  2070
<212>  DNA
<213>  Homo sapiens

<400>  8572
ctcccaggtg cctggcagag agtcctcacc agccccctgc cggatgtctg gctggcatct     60

gaggggactg aacatggcaa gaagcaaaac agcagcacaa gaaaccagtt tcttcatctg    120

aaaccgagca ggctctactc cagaacagaa cccacagtcc caggcgctgg gccttcttct    180

taagttggga aatcactcat ccccaggaga aaaaaagagc aaaagcttcc agtactgggg    240

atgtggggag aggtttttta aaaatatcag cccaacatat gggaaaatat gggatgcagg    300

catccccagg tgtcaagcgt ccagatccgt agacacactg ggacgatggt gatcagtatc    360

actccctctg actcatcggc cctacaggga agacaccatg ctggtgcaca gtcggtgcca    420

aacccgcgtt tgtaaatgaa taagtgttgc tgccctggtg gaagcccagc tcatgtggag    480

gaagccagct tgcagagaga gcaagaacag agccagcaca cacattggag caaaggcaag    540

ggcagatgga aagttctggc ggcatcatgc caaggctccc atccgaggcc tccctgaacc    600

ccactctctc ggcgccacct tggatgctgc gggctggtac attccccact tgcaaaactc    660

tgtggggctg ggttcctctc ttttctttcc aaatatccca ggaagtggat ggttttatcc    720

aaattcagca gacgagtaaa aagagtcttc gggaggtgca atagctttct aggaatgagg    780

atattcttca aggaaaatga accccacact aggcctggcc atttttctgg ctgttctcct    840

cacggtgaaa ggtcttctaa agccgagctt ctcaccaagg aattataaag ctttgagcga    900

ggtccaagga tggaagcaaa ggatggcagc caaggagctt gcaaggcaga acatggactt    960

aggctttaag ctgctcaaga agctggcctt ttacaaccct ggcaggaaca tcttcctatc   1020

ccccttgagc atctctacag ctttctccat gctgtgcctg ggtgcccagg acagcaccct   1080

ggacgagatc aagcaggggt tcaacttcag aaagatgcca gaaaaagatc ttcatgaggg   1140

cttccattac atcatccacg agctgaccca gaagacccag gacctcaaac tgagcattgg   1200

gaacacgctg ttcattgacc agaggctgca gccacagcgt aagtttttgg aagatgccaa   1260

gaacttttac agtgccgaaa ccatccttac caactttcag aatttggaaa tggctcagaa   1320

gcagatcaat gactttatca gtcaaaaaac ccatgggaaa attaacaacc tgatcgagaa   1380

tatagacccc ggcactgtga tgcttcttgc aaattatatt ttctttcgag ccaggtggaa   1440

acatgagttt gatccaaatg taactaaaga ggaagatttc tttctggaga aaaacagttc   1500

agtcaaggtg cccatgatgt tccgtagtgg catataccaa gttggctatg acgataagct   1560

ctcttgcacc atcctggaaa taccctacca gaaaaatatc acagccatct tcatccttcc   1620

tgatgagggc aagctgaagc acttggagaa gggattgcag gtggacactt tctccagatg   1680

gaaaacatta ctgtcacgca gggtcgtaga cgtgtctgta cccagactcc acatgacggg   1740

caccttcgac ctgaagaaga ctctctccta cataggtgtc tccaaaatct ttgaggaaca   1800

tggtgatctc accaagatcg cccctcatcg cagcctgaaa gtgggcgagg ctgtgcacaa   1860

ggctgagctg aagatggatg agaggggtac ggaaggggcc gctggcaccg gagcacagac   1920

tctgcccatg gagacaccac tcgtcgtcaa gatagacaaa ccctatctgc tgctgattta   1980

cagcgagaaa ataccttccg tgctcttcct gggaaagatt gttaacccta ttggaaaata   2040

aaggagaatt cctgcttgcc acagaccccg                                    2070


<210>  8573
<211>  414
<212>  PRT
<213>  Homo sapiens

<400>  8573

Met Asn Pro Thr Leu Gly Leu Ala Ile Phe Leu Ala Val Leu Leu Thr 
1               5                   10                  15


Val Lys Gly Leu Leu Lys Pro Ser Phe Ser Pro Arg Asn Tyr Lys Ala 
            20                  25                  30


Leu Ser Glu Val Gln Gly Trp Lys Gln Arg Met Ala Ala Lys Glu Leu 
        35                  40                  45


Ala Arg Gln Asn Met Asp Leu Gly Phe Lys Leu Leu Lys Lys Leu Ala 
    50                  55                  60


Phe Tyr Asn Pro Gly Arg Asn Ile Phe Leu Ser Pro Leu Ser Ile Ser 
65                  70                  75                  80


Thr Ala Phe Ser Met Leu Cys Leu Gly Ala Gln Asp Ser Thr Leu Asp 
                85                  90                  95


Glu Ile Lys Gln Gly Phe Asn Phe Arg Lys Met Pro Glu Lys Asp Leu 
            100                 105                 110


His Glu Gly Phe His Tyr Ile Ile His Glu Leu Thr Gln Lys Thr Gln 
        115                 120                 125


Asp Leu Lys Leu Ser Ile Gly Asn Thr Leu Phe Ile Asp Gln Arg Leu 
    130                 135                 140


Gln Pro Gln Arg Lys Phe Leu Glu Asp Ala Lys Asn Phe Tyr Ser Ala 
145                 150                 155                 160


Glu Thr Ile Leu Thr Asn Phe Gln Asn Leu Glu Met Ala Gln Lys Gln 
                165                 170                 175


Ile Asn Asp Phe Ile Ser Gln Lys Thr His Gly Lys Ile Asn Asn Leu 
            180                 185                 190


Ile Glu Asn Ile Asp Pro Gly Thr Val Met Leu Leu Ala Asn Tyr Ile 
        195                 200                 205


Phe Phe Arg Ala Arg Trp Lys His Glu Phe Asp Pro Asn Val Thr Lys 
    210                 215                 220


Glu Glu Asp Phe Phe Leu Glu Lys Asn Ser Ser Val Lys Val Pro Met 
225                 230                 235                 240


Met Phe Arg Ser Gly Ile Tyr Gln Val Gly Tyr Asp Asp Lys Leu Ser 
                245                 250                 255


Cys Thr Ile Leu Glu Ile Pro Tyr Gln Lys Asn Ile Thr Ala Ile Phe 
            260                 265                 270


Ile Leu Pro Asp Glu Gly Lys Leu Lys His Leu Glu Lys Gly Leu Gln 
        275                 280                 285


Val Asp Thr Phe Ser Arg Trp Lys Thr Leu Leu Ser Arg Arg Val Val 
    290                 295                 300


Asp Val Ser Val Pro Arg Leu His Met Thr Gly Thr Phe Asp Leu Lys 
305                 310                 315                 320


Lys Thr Leu Ser Tyr Ile Gly Val Ser Lys Ile Phe Glu Glu His Gly 
                325                 330                 335


Asp Leu Thr Lys Ile Ala Pro His Arg Ser Leu Lys Val Gly Glu Ala 
            340                 345                 350


Val His Lys Ala Glu Leu Lys Met Asp Glu Arg Gly Thr Glu Gly Ala 
        355                 360                 365


Ala Gly Thr Gly Ala Gln Thr Leu Pro Met Glu Thr Pro Leu Val Val 
    370                 375                 380


Lys Ile Asp Lys Pro Tyr Leu Leu Leu Ile Tyr Ser Glu Lys Ile Pro 
385                 390                 395                 400


Ser Val Leu Phe Leu Gly Lys Ile Val Asn Pro Ile Gly Lys 
                405                 410


<210>  8574
<211>  1528
<212>  DNA
<213>  Homo sapiens

<400>  8574
aagtgagtcg gcggaagtgg gagcgcggca agcggatgga gccagcgaga aacacatagc     60

cagggttctg tcgcatgacc cccgacggca cctgctcccc atcagcagca tcatactccg    120

atggataaac tgagggctca gtgggtcatg acctgcccag agtcatggag ggagtgagag    180

gcagagccag gatgagctcc caggccctga aacttctggg ccagtggcct acacacagag    240

cttcccaccc ttcctcattg ggtttctgca agccctcccc accccagcac tctgcagggc    300

ctgggaagtg aaccagctgg gaggattctt agagaagaaa agtgctgatt taagagaaac    360

tgcattattt gtgaaataca aaattcatct tgtgggtgta agagatgcct tcgtggacgg    420

atgaagctcc tggtactaag tagcaggagt gcagtgaagc tgctgtgttc tccagctcgt    480

agttaagggc cagtcaggat cagacatctt gccctgatgg aaaagaagat gaacagatac    540

ctcctgacct ggatagcaat taattctggg gacctagatc cccaaggact ttaggatgag    600

gcagcagttt ggatttagga tcaacatggt atttaaaata taaaagcatt gtagtgttgg    660

ggaagcatca tttaaaagaa cttgtggggt ccctgtcagg cccctcttga gacaggccag    720

ccccacagaa gagaaggcct agggctggct ccctagggtt gtgagaaact ccagaacagt    780

gttgacttct ttcttcccct agggtcacac cagcatgtag catgatgcct tgcacacagt    840

aggtgctcag taaacacttt tggaccactg aatgcaatga ccaatggata aaaacattgt    900

tcttcccttg accagataag acccgcttcc ctgggcgtcc acaggccgct ggtgatgcac    960

actcttctct gtgtggcctc tgcctgccgg gggaagcctt gtgaccagtt tctccccgct   1020

gagtcaaggg agaatgaggg ggagcatgaa catttgcttg tttcccttat ggcttctgaa   1080

tctttatttt atttttttta atgaaaatgt ctacttgaat ttaggtaagg aagaccttgc   1140

tcttagtttt tgaattttga actagaaaaa aaaaaaaggt ctttcaatga acactagcag   1200

aacagtctaa gcaatcatga taaagaccta attcctgcct ctttctcctg ctctgatgga   1260

gctgatgaca gcacaaatgg gagagggaga atgtagcaag gacactgaag gacagagagt   1320

tgtccaagcc accaggaagg tgaaagtggg aattcatttt ctgtgccatt gggtggttcc   1380

ttaggaaaaa acgtagacaa agaaaaatat tgtattattt gtggaaatca agttcgtatt   1440

gcaggtgtaa gaaatgtctt tgtgggttga cagcatttat tgaacatgag cctttatttt   1500

tggagctcct ccaacgtacc atgcactg                                      1528


<210>  8575
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  8575

Met His Thr Leu Leu Cys Val Ala Ser Ala Cys Arg Gly Lys Pro Cys 
1               5                   10                  15


Asp Gln Phe Leu Pro Ala Glu Ser Arg Glu Asn Glu Gly Glu His Glu 
            20                  25                  30


His Leu Leu Val Ser Leu Met Ala Ser Glu Ser Leu Phe Tyr Phe Phe 
        35                  40                  45


<210>  8576
<211>  481
<212>  DNA
<213>  Homo sapiens

<400>  8576
atagctggta aagcactctt tctgggtgtg tctgtaagag tgtttctgga agagattagc     60

atttgcatgg gtagactgag taaagaagac ctgttctcac caagtaagtg ggcatcatcc    120

aatccactga gagcccagat tgaacaaaaa cacagagaga aattcccagc atatcctgca    180

tctcattctt ggtgtgaagc aggaacacgc actcattcct atttggctat agtcttcaca    240

gctttctact gtttctttta aaagaaggaa actaaaataa tataattcaa tgttgtccag    300

tcagctttga ttactgtcgg tccctgtgtg tgaagtgctg tgctggcttg aacgggacat    360

gcaaaaatca agaaggcaag gtccagtcct taaagcccta gagcaagggt tgacaaacca    420

cagtacttgg gctaaaccca gcccaccacc tgtttttgca aataaagttt tattggaaca    480

c                                                                    481


<210>  8577
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8577

Met Gly Arg Leu Ser Lys Glu Asp Leu Phe Ser Pro Ser Lys Trp Ala 
1               5                   10                  15


Ser Ser Asn Pro Leu Arg Ala Gln Ile Glu Gln Lys His Arg Glu Lys 
            20                  25                  30


Phe Pro Ala Tyr Pro Ala Ser His Ser Trp Cys Glu Ala Gly Thr Arg 
        35                  40                  45


Thr His Ser Tyr Leu Ala Ile Val Phe Thr Ala Phe Tyr Cys Phe Phe 
    50                  55                  60


<210>  8578
<211>  2203
<212>  DNA
<213>  Homo sapiens

<400>  8578
cactgtggaa gctttgttct tttgctcttt gcaataaatc ttgctactgc tcactctttg     60

ggtccacgct gcttttatga gctgtaacac tcaccgcgaa gatctgcagc ttcactcctg    120

agcccagcaa gaccacgagc ccaccgggag gaatgaacaa ctccagacac gctaccttaa    180

gagctgtacc actcaccgcg aaggtctgca gcttcactcc tgagccagcg agaccacgaa    240

cccaccagaa ggaagaaact ccgaacacat ctgaacatca gaagggacag actccagaca    300

cgccacctta agagctgtaa cactcaccgc gagggtccac ggcttcattc ttgaagtcag    360

tgagaccaag aacccaccaa ttccggacac agtgctgaga atcatgcctt gaaatctagc    420

agctctgtta aaaactgagc aaggtgtact tcggggttgt gttgagaagg ttggtgttca    480

gctaaatcag gagggaaggc caaggaaaat caggcttggc acctgtcaac agcttgtttt    540

catttccttt ccaatttaag aatgtgttta acattctatc ccagacaatg tgatggtcat    600

gaagtctctg tcagagagga aagagggagt taatctataa tgaagatcaa cagtgaagag    660

gaaaggggtc ttccctggaa cgcttcagtc atatacgaca ttttacacaa caataatgga    720

cctgtgtaag gaggtatgtg tgggagaaga ttccagaagg tcttgagaca ctccagatga    780

aggttggtgt ggggctgtgc tgctggagca ccagagagtg aaaagaggtt atctccctct    840

gtgccaggcc agagtgcagt ggtgcaatca cggctcactg tagtctcaac ctcctgggct    900

caagagatcc tcccacttca gcctcccaag cagctaagac tacagttatt ttattcttat    960

gagcttgtgg gctccatcta ccaacctctg ggcaaatgct catctgactt ccatagacac   1020

acagcaagca gacaaccaca caaagaggaa gagggagaat atttaccagc catggaacat   1080

ctgctctgtg cttatatctc atatgcatta tctctaatta tcaaaagaag acatgtcctt   1140

aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact tcttggttta   1200

caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag gagcagaatg   1260

ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc agagagtgga   1320

tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc caggtttcct   1380

gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca gttcaccttc   1440

cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag ccaaagaggg   1500

gacagcagtg gttagaagca aggcacaagt catacctaca ttcaaggaga ggggaccatg   1560

caaaggataa actgcagaga gacaacagat ttacatccca gacacattca cactgggcca   1620

agagcagctg ccattgcaga ttcgagtcac gtcctttttt ccttccttct ccttcttgga   1680

gttacaacag aagctgggga ggtgagagtg cagaaaggac gtggatgaag cagagaggca   1740

cgtgcctgtc tcattcgcct ctggatctgc tgcatccagg actgtgccag cacaaagtgg   1800

gagcccgata aatatttatt gaagaaatga aaggtgacaa aaggcagaag gagggagacc   1860

ccaaaaagag gtaaatttgg tatcttagca agtgggtgac taccactgtc tgggggaaag   1920

ctgatacacg aggacttgac aataattaca gcagtaacaa tcgctactat tttgttttga   1980

gatgaatttt agtttctgaa attgtccaaa gcacttttat caatagaaac ttgttacaca   2040

tccctccaac agggagaagc agcacaggaa gctgccccct caaacactaa aggctcctgg   2100

agctattcac agtgctgggg aacaaccaga ggaggaggag gacagaggga gagaatactt   2160

tttttaaaaa tcccaaacaa aaccaaattc tatacatgta tat                     2203


<210>  8579
<211>  163
<212>  PRT
<213>  Homo sapiens

<400>  8579

Met Ala Lys Ser Lys Val Thr Gln Pro Ser Ala Ser Glu Gln Arg Arg 
1               5                   10                  15


Ile Gln Val Ser Cys Pro Ser Ala Leu Ser Ala Ala His Ala Thr Cys 
            20                  25                  30


Phe His Ala Ile Ser Val His Leu Pro Ala Thr His Leu Gln Ser Glu 
        35                  40                  45


Thr Glu Ser Leu Arg Val Cys Val Glu Pro Lys Arg Gly Gln Gln Trp 
    50                  55                  60


Leu Glu Ala Arg His Lys Ser Tyr Leu His Ser Arg Arg Gly Asp His 
65                  70                  75                  80


Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg Phe Thr Ser Gln Thr His 
                85                  90                  95


Ser His Trp Ala Lys Ser Ser Cys His Cys Arg Phe Glu Ser Arg Pro 
            100                 105                 110


Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr Asn Arg Ser Trp Gly Gly 
        115                 120                 125


Glu Ser Ala Glu Arg Thr Trp Met Lys Gln Arg Gly Thr Cys Leu Ser 
    130                 135                 140


His Ser Pro Leu Asp Leu Leu His Pro Gly Leu Cys Gln His Lys Val 
145                 150                 155                 160


Gly Ala Arg 



<210>  8580
<211>  2810
<212>  DNA
<213>  Homo sapiens

<400>  8580
cacgctgctt ttatgagctg taacactcac cgcgaagatc tgcagcttca ctcctgagcc     60

cagcaagacc acgagcccac cgggaggaat gaacaactcc agacacgcta ccttaagagc    120

tgtaccactc accgcgaagg tctgcagctt cactcctgag ccagcgagac cacgaaccca    180

ccagaaggaa gaaactccga acacatctga acatcagaag ggacagactc cagacacgcc    240

accttaagag ctgtaacact caccgcgagg gtccacggct tcattcttga agtcagtgag    300

accaagaacc caccaattcc ggacacagtg ctgagaatca tgccttgaaa tctagcagct    360

ctgttaaaaa ctgagcaagg tgtacttcgg ggttgtgttg agaaggttgg tgttcagcta    420

aatcaggagg gaaggccaag gaaaatcagg cttggcacct gtcaacaggt gggacccaat    480

agccaagcaa atggtcctgc aaactgtact acccaacgtt cacagcaagg attccaactt    540

ctcaccaggg catggaaaat ttgccttcat gtcaaccacc accttagccc ttgactaccc    600

aacggactct tcccaagtca acagccactt cctccctggg gcttaacagg cattccttga    660

agcctgcccc gggcagttag tccttccctt ttgtgtgaac tctcggctgt tttcgttgtc    720

tgcacacaga gcagtggtct agggagcgaa gggttttgga atggaccttt tcctttctta    780

gcttgctgta gggattgtgc ttcagctaag taaagtggaa aaacagaagt acaaaagcaa    840

cagccccaga tctaagggca ccgtagctct ggaatctgga ttttattcca gattcaaccc    900

tcagcaggga gttgaagtgg tcagccctgt gctttacaag gctgattggg cagcacccat    960

agtagaattg tcaatataaa gtaattgaaa ggatcagaat ccagggtttt cgttgttttt   1020

aagtttttaa gttttaaaaa caaagttgtt tttgttcgtt tttaagttta cttctcttta   1080

atcggtctca ctttattgac caggctggtt tcgaactcct gggcttaagt gatttctcct   1140

gtctcagctt ctcaaagtgc tgggattaca ggcgtgagcc gctgcaccca gcccagaatc   1200

cagttttaaa gagtttattc aagccaaaag ctgggaatgg ccatctgaga aacacagact   1260

ctaggaaaat ggggccaggg ccctgaagtt aaaagttaaa gtcttgctta cataggcaga   1320

aagcaaagac atttagtaac cttgtagaac attttcttgt ataacttttc ttgttttaac   1380

tttcttgttt aacattttct atgcaaggct ggtttatgag ttacaaccta taattaatta   1440

taggttgttc ccctgcctcc accttgtttt cttttctcta cagcttgttt tcatttcctt   1500

tccaatttaa gaatgtgttt aacattctat cccagacaat gtgatggtca tgaagtctct   1560

gtcagagagg aaagagggag ttaatctata atgaagatca acagtgaaga ggaaaggggt   1620

cttccctgga acgcttcagt catatacgac attttacaca acaataatgg acctgtgtaa   1680

ggaggtatgt gtgggagaag attccagaag gtcttgagac actccagatg aaggttggtg   1740

tggggctgtg ctgctggagc accagagagt gaaaagaggt tatctccctc tgtgccaggc   1800

cagagtgcag tggtgcaatc acggctcact gtagtctcaa cctcctgggc tcaagagatc   1860

ctcccacttc agcctcccaa gcagctaaga ctacagacat gtccttaacc ttggcacaac   1920

aaatctctaa atcgattgag acctgtctca gatacttctt ggtttacaag atggaggctg   1980

aaattaaaga gaaagatcct cactcaactc acagaggagc agaatgggaa gaggacttag   2040

tgagaattcc ctgaacacag gagaaaaccg aagcccagag agtggatggc caagtccaag   2100

gtcacacagc caagtgcatc cgagcagcgc aggatccagg tttcctgccc cagtgctctt   2160

tctgcagccc atgccacctg ttttcatgct atctcagttc accttccagc tacacacctg   2220

caatcagaaa cagaaagtct gagagtgtgt gtggagccaa agaggggaca gcagtggtta   2280

gaagcaaggc acaagtcata cctacattca aggagagggg accatgcaaa ggataaactg   2340

cagagagaca acagatttac atcccagaca cattcacact gggccaagag cagctgccat   2400

tgcagattcg agtcacgtcc ttttttcctt ccttctcctt cttggagtta caacagaagc   2460

tggggaggtg agagtgcaga aaggacgtgg atgaagcaga gaggcacgtg cctgtctcat   2520

tcgcctctgg atctgctgca tccaggactg tgccagcaca aagtgggagc ccgataaata   2580

tttattgaag aaatgaaagg tgacaaaagg cagaaggagg gagaccccaa aaagagcagc   2640

acaggaagct gccccctcaa acactaaagg ctcctggagc tattcacagt gctggggaac   2700

aaccagagga ggaggaggac agagggagag aatacttttt ttaaaaatcc caaacaaaac   2760

caaattctat acatgtatat ctcgagtgag taaatgtgta acactcagca              2810


<210>  8581
<211>  163
<212>  PRT
<213>  Homo sapiens

<400>  8581

Met Ala Lys Ser Lys Val Thr Gln Pro Ser Ala Ser Glu Gln Arg Arg 
1               5                   10                  15


Ile Gln Val Ser Cys Pro Ser Ala Leu Ser Ala Ala His Ala Thr Cys 
            20                  25                  30


Phe His Ala Ile Ser Val His Leu Pro Ala Thr His Leu Gln Ser Glu 
        35                  40                  45


Thr Glu Ser Leu Arg Val Cys Val Glu Pro Lys Arg Gly Gln Gln Trp 
    50                  55                  60


Leu Glu Ala Arg His Lys Ser Tyr Leu His Ser Arg Arg Gly Asp His 
65                  70                  75                  80


Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg Phe Thr Ser Gln Thr His 
                85                  90                  95


Ser His Trp Ala Lys Ser Ser Cys His Cys Arg Phe Glu Ser Arg Pro 
            100                 105                 110


Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr Asn Arg Ser Trp Gly Gly 
        115                 120                 125


Glu Ser Ala Glu Arg Thr Trp Met Lys Gln Arg Gly Thr Cys Leu Ser 
    130                 135                 140


His Ser Pro Leu Asp Leu Leu His Pro Gly Leu Cys Gln His Lys Val 
145                 150                 155                 160


Gly Ala Arg 



<210>  8582
<211>  3923
<212>  DNA
<213>  Homo sapiens

<400>  8582
cacgctgctt ttatgagctg taacactcac cgcgaagatc tgcagcttca ctcctgagcc     60

cagcaagacc acgagcccac cgggaggaat gaacaactcc agacacgcta ccttaagagc    120

tgtaccactc accgcgaagg tctgcagctt cactcctgag ccagcgagac cacgaaccca    180

ccagaaggaa gaaactccga acacatctga acatcagaag ggacagactc cagacacgcc    240

accttaagag ctgtaacact caccgcgagg gtccacggct tcattcttga agtcagtgag    300

accaagaacc caccaattcc ggacacagtg ctgagaatca tgccttgaaa tctagcagct    360

ctgttaaaaa ctgagcaagg tgtacttcgg ggttgtgttg agaaggttgg tgttcagcta    420

aatcaggagg gaaggccaag gaaaatcagg cttggcacct gtcaacaggt gggacccaat    480

agccaagcaa atggtcctgc aaactgtact acccaacgtt cacagcaagg attccaactt    540

ctcaccaggg catggaaaat ttgccttcat gtcaaccacc accttagccc ttgactaccc    600

aacggactct tcccaagtca acagccactt cctccctggg gcttaacagg cattccttga    660

agcctgcccc gggcagttag tccttccctt ttgtgtgaac tctcggctgt tttcgttgtc    720

tgcacacaga gcagtggtct agggagcgaa gggttttgga atggaccttt tcctttctta    780

gcttgctgta gggattgtgc ttcagctaag taaagtggaa aaacagaagt acaaaagcaa    840

cagccccaga tctaagggca ccgtagctct ggaatctgga ttttattcca gattcaaccc    900

tcagcaggga gttgaagtgg tcagccctgt gctttacaag gctgattggg cagcacccat    960

agtagaattg tcaatataaa gtaattgaaa ggatcagaat ccagggtttt cgttgttttt   1020

aagtttttaa gttttaaaaa caaagttgtt tttgttcgtt tttaagttta cttctcttta   1080

atcggtctca ctttattgac caggctggtt tcgaactcct gggcttaagt gatttctcct   1140

gtctcagctt ctcaaagtgc tgggattaca ggcgtgagcc gctgcaccca gcccagaatc   1200

cagttttaaa gagtttattc aagccaaaag ctgggaatgg ccatctgaga aacacagact   1260

ctaggaaaat ggggccaggg ccctgaagtt aaaagttaaa gtcttgctta cataggcaga   1320

aagcaaagac atttagtaac cttgtagaac attttcttgt ataacttttc ttgttttaac   1380

tttcttgttt aacattttct atgcaaggct ggtttatgag ttacaaccta taattaatta   1440

taggttgttc ccctgcctcc accttgtttt cttttctcta cagcttgttt tcatttcctt   1500

tccaatttaa gaatgtgttt aacattctat cccagacaat gtgatggtca tgaagtctct   1560

gtcagagagg aaagagggag ttaatctata atgaagatca acagtgaaga ggaaaggggt   1620

cttccctgga acgcttcagt catatacgac attttacaca acaataatgg acctgtgtaa   1680

ggaggtatgt gtgggagaag attccagaag gtcttgagac actccagatg aaggttggtg   1740

tggggctgtg ctgctggagc accagagagt gaaaagaggt tatctccctc tgtgccaggc   1800

cagagtgcag tggtgcaatc acggctcact gtagtctcaa cctcctgggc tcaagagatc   1860

ctcccacttc agcctcccaa gcagctaaga ctacagttat tttattctta tgagcttgtg   1920

ggctccatct accaacctct gggcaaatgc tcatctgact tccatagaca cacagcaagc   1980

agacaaccac acaaagagga agagggagaa tatttaccag ccatggaaca tctgctctgt   2040

gcttatatct catatgcatt atctctaatt atcaaaagaa ggttagaagc aaggcacaag   2100

tcatacctac attcaaggag aggggaccat gcaaaggata aactgcagag agacaacaga   2160

tttacatccc agacacattc acactgggcc aagagcagct gccattgcag attcgagtca   2220

cgtccttttt tccttccttc tccttcttgg agttacaaca gaagctgggg aggtgagagt   2280

gcagaaagga cgtggatgaa gcagagaggc acgtgcctgt ctcattcgcc tctggatctg   2340

ctgcatccag gactgtgcca gcacaaagtg ggagcccgat aaatatttat tgaagaaatg   2400

aaaggtgaca aaaggcagaa ggagggagac cccaaaaaga gagatgggat cccactatat   2460

tgcacaggct ggtctcaaac tcctgagctc aagcgatcct cctgccttgg cctcccacgg   2520

tgctgagact acaggtgtga gccaccactc ccagcctgat ttatatttta taaagaggca   2580

acgatggagt acacagctga gcaatctctt gcatttctgg accttgagca tcaggaagct   2640

tagggagggt gaaaactcag aagaaagctc agagttgaga cctttgattt tttgcccaga   2700

gagtccagct aacacacttt ataacccaaa aggccttaca aatatttcag agcagaggca   2760

gcatttttgc actggataaa caaaggtacg gtaatttctt catagtttat tttcattaca   2820

agtaattctt ttcctgaaga aaaatttata tttcagattt atttcccctc tcaaagggga   2880

ggggagttat aatattctgt ttccatagca ccattcctca agatcaaacc caggcaggca   2940

tttttacagc acacacttcc atatgtcatt gctaatcctc gcaaccttga ggaaactgag   3000

gtgcaaaggg gttgaggaat gtgttcacca tcccaaagcc aacgaagtgc cagaacccaa   3060

atccaagctt ggctgtctca tccccaagga cgtactcttt atgccgttcc ttatgacttt   3120

tcatgcagca ggtgcaaggc agcaagaatt tggctcttct gacatttatc aggcacctgg   3180

tatgtgccag gcctactgta aaccccaaga tgacatggtc catgtctatc cattcagcat   3240

cagagagact gttatcagga cttgaggcct gagacacagc cctgaatcag atgcaggcct   3300

ctggtgtttg caaaggatgc gtgagtatgt gtatgtgtat gcgtgcattg tgtgtagggg   3360

tgtgtgtatg ttgggggttg ggggcagaaa atgctccctg aactgttggt attaaggcag   3420

atctttgatg gagggactgg ggtgtggaga cttgaaccct agtttcaaag tggggacctc   3480

gaacactagt atggccagca gacaggctgg agttgctgaa ttgtcagcta ggtctttaat   3540

ccactcccct tctctaaatc agggtggaat tggactcagg gctggttcag ggctgaggtt   3600

tccgggggat gaatgattcc agacagtggg aaggggtgat ggatgatgaa cctggcaagt   3660

cacaggacta tggacttggc tgtatgttgc atgtatgtgt aagatctgag ttgagacctt   3720

tgatttttgc ccagaaagtc cagctaacat actatataag ccagtgagac cagccagtgt   3780

ctgttcattg cctctgcctt gcccctatgc ctgcccgcct cctatagcag gtccctatag   3840

cataatgaaa atgcgaacaa ccttttctct ggacactggg gaatctagtc tggtggataa   3900

agatggatgg ctgttaaacg atc                                           3923


<210>  8583
<211>  119
<212>  PRT
<213>  Homo sapiens

<400>  8583

Met Glu His Leu Leu Cys Ala Tyr Ile Ser Tyr Ala Leu Ser Leu Ile 
1               5                   10                  15


Ile Lys Arg Arg Leu Glu Ala Arg His Lys Ser Tyr Leu His Ser Arg 
            20                  25                  30


Arg Gly Asp His Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg Phe Thr 
        35                  40                  45


Ser Gln Thr His Ser His Trp Ala Lys Ser Ser Cys His Cys Arg Phe 
    50                  55                  60


Glu Ser Arg Pro Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr Asn Arg 
65                  70                  75                  80


Ser Trp Gly Gly Glu Ser Ala Glu Arg Thr Trp Met Lys Gln Arg Gly 
                85                  90                  95


Thr Cys Leu Ser His Ser Pro Leu Asp Leu Leu His Pro Gly Leu Cys 
            100                 105                 110


Gln His Lys Val Gly Ala Arg 
        115


<210>  8584
<211>  601
<212>  DNA
<213>  Homo sapiens

<400>  8584
catttccttt ccaatttaag aatgtgttta acattctatc ccagacaatg tgatggtcat     60

gaagtctctg tcagagagga aagagggagt taatctataa tgaagatcaa cagtgaagag    120

gaaaggggtc ttccctggaa cgcttcagtc atatacgaca ttttacacaa caataatgga    180

cctgtgtaag gaggtatgtg tgggagaaga ttccagaagg tcttgagaca ctccagatga    240

aggttggtgt ggggctgtgc tgctggagca ccagagagtg aaaagaggtt atctccctct    300

gtgccaggcc agagtgcagt ggtgcaatca cggctcactg tagtctcaac ctcctgggct    360

caagagatcc tcccacttca gcctcccaag cagctaagac tacaggcacg tgtcatcata    420

tctggcaaat taaaaaaaaa attatagaga tgggctctcc ctgtgtttcc ctggttggtc    480

tcaaactcct gggctcaagt gatcctccca tcttggcctc ccaacttact gggattacag    540

gcatttgcca ctgtgcccag cccatttcaa tatttctgat caataaatgt gcctgtcctt    600

c                                                                    601


<210>  8585
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  8585

Met Gly Ser Pro Cys Val Ser Leu Val Gly Leu Lys Leu Leu Gly Ser 
1               5                   10                  15


Ser Asp Pro Pro Ile Leu Ala Ser Gln Leu Thr Gly Ile Thr Gly Ile 
            20                  25                  30


Cys His Cys Ala Gln Pro Ile Ser Ile Phe Leu Ile Asn Lys Cys Ala 
        35                  40                  45


Cys 



<210>  8586
<211>  3780
<212>  DNA
<213>  Homo sapiens

<400>  8586
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa gatcacggga attacaagtg acatcctgaa gtatgatcac   1860

aaatgtttca aattaagcct tcctgctaag tttccagagg tgtgtggctc ggacgaagtg   1920

tttccagacc ctgatctact gcatgtcctg cctgttgctg gttctttgca gcagtccatt   1980

gaccaatgct gtctacagct tgagagcctc tgcaggccag ggctgctctg tgcacatcct   2040

acgttactat tcaaactgca cagcagcatg aaaaacaggc ccttcttttc tctcatttac   2100

acatatgtga agaagacaca gcaagtgaga aaacgtgacc gaaagccacg cggacaggtg   2160

gccgcagggc caaacccaac ttccgtgatg tgatctggct acagtttgga gcccacatat   2220

ttcaatagtt atccccaggc ctggcacgtc aaagaggctc cagaaatgtt tgctgagtga   2280

gtgatgaatc agcaatttct gattttctcc taaacttaga gaataagtgg cttgtctgca   2340

gtcacccagg gcgtccctga cagaggtaca agtaaagccc agatctctgc atctctggtt   2400

caaggccttt tgtactacac accgctgtct ctttgtcatc attaaaagca aggctcaagg   2460

gacatgtttt ctagccttag ttccccatct acaaaatggg cctcatggaa tggaatgtct   2520

ccacttcact ccagcatcaa caagtgggga attctgatgg attcaattcg acttctttcc   2580

atgggcgtgt tctaagcagc ctctttgttc cagaagctgc cctcagccag agttggataa   2640

gccaatcctc actccccagc ctcctctgga tagggatgaa gaccccactg gggttggaag   2700

tgcagaggca gacaggtgta tggagtcacc tgtaaattga ttcaagtgag ccaggaaagc   2760

agcaaaggaa agagaaacct gagtgacgac gtggtggagg aacagggctg gaaagaggct   2820

gctggctgtc tggcttcgca gctctggcct cctaatcagc ctcgctcttg tctctggtgt   2880

tctctggctc ttgtccatct gtctgtgttt ctttttgcca gctattgact aatctttgct   2940

gaagctgagc tagaattctg gtgtttataa gcaggtaact agctgagcac tagttgataa   3000

ctttggagtt agtggataac cacagggctg ggctactaag ctttttcagt tgaaaaataa   3060

ataaataaat aaataaacac cacacccagc taatttttgt atttttagta gagacagggt   3120

ttcaccgtgt tagccaggat ggactccatc tcctgacctc gtgatccgcc tacctcggcc   3180

tcccaaagtg ctgggattac aggcgtgagc caccacgccc ggtcaccttt gtcctgtttt   3240

ctacaggtta gaagcaaggc acaagtcata cctacattca aggagagggg accatgcaaa   3300

ggataaactg cagagagaca acagatttac atcccagaca cattcacact gggccaagag   3360

cagctgccat tgcagattcg agtcacgtcc ttttttcctt ccttctcctt cttggagtta   3420

caacagaagc tggggaggtg agagtgcaga aaggacgtgg atgaagcaga gaggcacgtg   3480

cctgtctcat tcgcctctgg atctgctgca tccaggactg tgccagcaca aagtgggagc   3540

ccgataaata tttattgaag aaatgaaagg tgacaaaagg cagaaggagg gagaccccaa   3600

aaagagcagc acaggaagct gccccctcaa acactaaagg ctcctggagc tattcacagt   3660

gctggggaac aaccagagga ggaggaggac agagggagag aatacttttt ttaaaaatcc   3720

caaacaaaac caaattctat acatgtatat ctcgagtgag taaatgtgta acactcagca   3780


<210>  8587
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8587

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8588
<211>  3663
<212>  DNA
<213>  Homo sapiens

<400>  8588
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa ggttagaagc aaggcacaag tcatacctac attcaaggag   1860

aggggaccat gcaaaggata aactgcagag agacaacaga tttacatccc agacacattc   1920

acactgggcc aagagcagct gccattgcag attcgagtca cgtccttttt tccttccttc   1980

tccttcttgg agttacaaca gaagctgggg aggtgagagt gcagaaagga cgtggatgaa   2040

gcagagaggc acgtgcctgt ctcattcgcc tctggatctg ctgcatccag gactgtgcca   2100

gcacaaagtg ggagcccgat aaatatttat tgaagaaatg aaaggtgaca aaaggcagaa   2160

ggagggagac cccaaaaaga gagatgggat cccactatat tgcacaggct ggtctcaaac   2220

tcctgagctc aagcgatcct cctgccttgg cctcccacgg tgctgagact acaggtgtga   2280

gccaccactc ccagcctgat ttatatttta taaagaggca acgatggagt acacagctga   2340

gcaatctctt gcatttctgg accttgagca tcaggaagct tagggagggt gaaaactcag   2400

aagaaagctc agagttgaga cctttgattt tttgcccaga gagtccagct aacacacttt   2460

ataacccaaa aggccttaca aatatttcag agcagaggca gcatttttgc actggataaa   2520

caaaggtacg gtaatttctt catagtttat tttcattaca agtaattctt ttcctgaaga   2580

aaaatttata tttcagattt atttcccctc tcaaagggga ggggagttat aatattctgt   2640

ttccatagca ccattcctca agatcaaacc caggcaggca tttttacagc acacacttcc   2700

atatgtcatt gctaatcctc gcaaccttga ggaaactgag gtgcaaaggg gttgaggaat   2760

gtgttcacca tcccaaagcc aacgaagtgc cagaacccaa atccaagctt ggctgtctca   2820

tccccaagga cgtactcttt atgccgttcc ttatgacttt tcatgcagca ggtgcaaggc   2880

agcaagaatt tggctcttct gacatttatc aggcacctgg tatgtgccag gcctactgta   2940

aaccccaaga tgacatggtc catgtctatc cattcagcat cagagagact gttatcagga   3000

cttgaggcct gagacacagc cctgaatcag atgcaggcct ctggtgtttg caaaggatgc   3060

gtgagtatgt gtatgtgtat gcgtgcattg tgtgtagggg tgtgtgtatg ttgggggttg   3120

ggggcagaaa atgctccctg aactgttggt attaaggcag atctttgatg gagggactgg   3180

ggtgtggaga cttgaaccct agtttcaaag tggggacctc gaacactagt atggccagca   3240

gacaggctgg agttgctgaa ttgtcagcta ggtctttaat ccactcccct tctctaaatc   3300

agggtggaat tggactcagg gctggttcag ggctgaggtt tccgggggat gaatgattcc   3360

agacagtggg aaggggtgat ggatgatgaa cctggcaagt cacaggacta tggacttggc   3420

tgtatgttgc atgtatgtgt aagatctgag ttgagacctt tgatttttgc ccagaaagtc   3480

cagctaacat actatataag ccagtgagac cagccagtgt ctgttcattg cctctgcctt   3540

gcccctatgc ctgcccgcct cctatagcag gtccctatag cataatgaaa atgcgaacaa   3600

ccttttctct ggacactggg gaatctagtc tggtggataa agatggatgg ctgttaaacg   3660

atc                                                                 3663


<210>  8589
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  8589

Met Asp Ala Trp Gly Arg Leu Glu Ala Arg His Lys Ser Tyr Leu His 
1               5                   10                  15


Ser Arg Arg Gly Asp His Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg 
            20                  25                  30


Phe Thr Ser Gln Thr His Ser His Trp Ala Lys Ser Ser Cys His Cys 
        35                  40                  45


Arg Phe Glu Ser Arg Pro Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr 
    50                  55                  60


Asn Arg Ser Trp Gly Gly Glu Ser Ala Glu Arg Thr Trp Met Lys Gln 
65                  70                  75                  80


Arg Gly Thr Cys Leu Ser His Ser Pro Leu Asp Leu Leu His Pro Gly 
                85                  90                  95


Leu Cys Gln His Lys Val Gly Ala Arg 
            100                 105


<210>  8590
<211>  3398
<212>  DNA
<213>  Homo sapiens

<400>  8590
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa gatcacggga attacaagtg acatcctgaa gtatgatcac   1860

aaatgtttca aattaagcct tcctgctaag tttccagagg tgtgtggctc ggacgaagtg   1920

tttccagacc ctgatctact gcatgtcctg cctgttgctg gttctttgca gcagtccatt   1980

gaccaatgct gtctacagct tgagagcctc tgcaggccag ggctgctctg tgcacatcct   2040

acgttactat tcaaactgca cagcagcatg aaaaacaggc ccttcttttc tctcatttac   2100

acatatgtga agaagacaca gcaagtgaga aaacgtgacc gaaagccacg cggacaggtg   2160

gccgcagggc caaacccaac ttccgtgatg tgatctggct acagtttgga gcccacatat   2220

ttcaatagtt atccccaggc ctggcacgtc aaagaggctc cagaaatgtt tgctgagtta   2280

gaagcaaggc acaagtcata cctacattca aggagagggg accatgcaaa ggataaactg   2340

cagagagaca acagatttac atcccagaca cattcacact gggccaagag cagctgccat   2400

tgcagattcg agtcacgtcc ttttttcctt ccttctcctt cttggagtta caacagaagc   2460

tggggaggtg agagtgcaga aaggacgtgg atgaagcaga gaggcacgtg cctgtctcat   2520

tcgcctctgg atctgctgca tccaggactg tgccagcaca aagtgggagc ccgataaata   2580

tttattgaag aaatgaaagg tgacaaaagg cagaaggagg gagaccccaa aaagagttac   2640

actggaagaa gagcccctcc ttccttcaag ccaagtcatc cccttgggct ctcaccactt   2700

cagtttatac cttgcctgta gtccagtctc tccagcatca attccatcag cacaaagaca   2760

taatttaatt ccttctacct taaaaaaaaa aaaaaaaaaa aaacagctct ccctctctta   2820

gggtgagatg aagtggttgg caacaggcca atgctacttt cagaggcgtt tgaatcagag   2880

tgactccatt ttgaataggg gttgagtaaa ataaggctga gacctactgg gctgcattcc   2940

catgagctta ggcattctaa gtcacaggat gagacaggag gtcagcacaa gatacacgtc   3000

acaaagacct tgctgataaa acagattgtg ataagaaaag ccagtcaaaa cccaccaaaa   3060

ccaagatggc gacaaaagtg atctctggtt gtcctcactg ctgattattc actaattata   3120

aaattaacat gataaaagac actcccacca gcaccgtgac agtttacaaa tgacatggac   3180

acatcaggaa gttaccctat atgtctaaaa ggggaggagc cctccattcc aattgtccac   3240

ccctttcctg gaaaactcat gaataatcca ccccttgttt agcatataat caagaaataa   3300

ccatgaaaat agccaaccag cagccctcag ggctgctttg cctatggagt agccattcta   3360

tattccttta ctttcttaat aaacttgctt tcacttta                           3398


<210>  8591
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8591

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8592
<211>  4232
<212>  DNA
<213>  Homo sapiens

<400>  8592
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa gatcacggga attacaagtg acatcctgaa gtatgatcac   1860

aaatgtttca aattaagcct tcctgctaag tttccagagg tgtgtggctc ggacgaagtg   1920

tttccagacc ctgatctact gcatgtcctg cctgttgctg gttctttgca gcagtccatt   1980

gaccaatgct gtctacagct tgagagcctc tgcaggccag ggctgctctg tgcacatcct   2040

acgttactat tcaaactgca cagcagcatg aaaaacaggc ccttcttttc tctcatttac   2100

acatatgtga agaagacaca gcaagtgaga aaacgtgacc gaaagccacg cggacaggtg   2160

gccgcagggc caaacccaac ttccgtgatg tgatctggct acagtttgga gcccacatat   2220

ttcaatagtt atccccaggc ctggcacgtc aaagaggctc cagaaatgtt tgctgagtga   2280

gtgatgaatc agcaatttct gattttctcc taaacttaga gaataagtgg cttgtctgca   2340

gtcacccagg gcgtccctga cagaggtaca agtaaagccc agatctctgc atctctggtt   2400

caaggccttt tgtactacac accgctgtct ctttgtcatc attaaaagca aggctcaagg   2460

gacatgtttt ctagccttag ttccccatct acaaaatggg cctcatggaa tggaatgtct   2520

ccacttcact ccagcatcaa caagtgggga attctgatgg attcaattcg acttctttcc   2580

atgggcgtgt tctaagcagc ctctttgttc cagaagctgc cctcagccag agttggataa   2640

gccaatcctc actccccagc ctcctctgga tagggatgaa gaccccactg gggttggaag   2700

tgcagaggca gacaggtgta tggagtcacc tgtaaattga ttcaagtgag ccaggaaagc   2760

agcaaaggaa agagaaacct gagtgacgac gtggtggagg aacagggctg gaaagaggct   2820

gctggctgtc tggcttcgca gctctggcct cctaatcagc ctcgctcttg tctctggtgt   2880

tctctggctc ttgtccatct gtctgtgttt ctttttgcca gctattgact aatctttgct   2940

gaagctgagc tagaattctg gtgtttataa gcaggtaact agctgagcac tagttgataa   3000

ctttggagtt agtggataac cacagggctg ggctactaag ctttttcagt tgaaaaataa   3060

ataaataaat aaataaacac cacacccagc taatttttgt atttttagta gagacagggt   3120

ttcaccgtgt tagccaggat ggactccatc tcctgacctc gtgatccgcc tacctcggcc   3180

tcccaaagtg ctgggattac aggcgtgagc caccacgccc ggtcaccttt gtcctgtttt   3240

ctacaggtta gaagcaaggc acaagtcata cctacattca aggagagggg accatgcaaa   3300

ggataaactg cagaaaggac gtggatgaag cagagaggca cgtgcctgtc tcattcgcct   3360

ctggatctgc tgcatccagg actgtgccag cacaaagtgg gagcccgata aatatttatt   3420

gaagaaatga aaggtgacaa aaggcagaag gagggagacc ccaaaaagag ttacactgga   3480

agaagagccc ctccttcctt caagccaagt catccccttg ggctctcacc acttcagttt   3540

ataccttgcc tgtagtccag tctctccagc atcaattcca tcagcacaaa gacataattt   3600

aattccttct accttaaaaa aaaaaaaaaa aaaaaaacag ctctccctct cttagggtga   3660

gatgaagtgg ttggcaacag gccaatgcta ctttcagagg cgtttgaatc agagtgactc   3720

cattttgaat aggggttgag taaaataagg ctgagaccta ctgggctgca ttcccatgag   3780

cttaggcatt ctaagtcaca ggatgagaca ggaggtcagc acaagataca cgtcacaaag   3840

accttgctga taaaacagat tgtgataaga aaagccagtc aaaacccacc aaaaccaaga   3900

tggcgacaaa agtgatctct ggttgtcctc actgctgatt attcactaat tataaaatta   3960

acatgataaa agacactccc accagcaccg tgacagttta caaatgacat ggacacatca   4020

ggaagttacc ctatatgtct aaaaggggag gagccctcca ttccaattgt ccaccccttt   4080

cctggaaaac tcatgaataa tccacccctt gtttagcata taatcaagaa ataaccatga   4140

aaatagccaa ccagcagccc tcagggctgc tttgcctatg gagtagccat tctatattcc   4200

tttactttct taataaactt gctttcactt ta                                 4232


<210>  8593
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8593

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8594
<211>  3132
<212>  DNA
<213>  Homo sapiens

<400>  8594
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa ggttagaagc aaggcacaag tcatacctac attcaaggag   1860

aggggaccat gcaaaggata aactgcagag agacaacaga tttacatccc agacacattc   1920

acactgggcc aagagcagct gccattgcag attcgagtca cgtccttttt tccttccttc   1980

tccttcttgg agttacaaca gaagctgggg aggtgagagt gcagaaagga cgtggatgaa   2040

gcagagaggc acgtgcctgt ctcattcgcc tctggatctg ctgcatccag gactgtgcca   2100

gcacaaagtg ggagcccgat aaatatttat tgaagaaatg aaaggtgaca aaaggcagaa   2160

ggagggagac cccaaaaaga gtatgaaccc agcatcacag tgcacttgtg gcagatggca   2220

gtgcataccc gggagctact ctcctccggc cagatgccct tctcccagct gcccgccgtg   2280

tggcagctct accccgggag gaagtaccga gcagcggatt ccagtttctg ggaaatagca   2340

gaccatggcc agattgactc tatggagcag ctggtcctaa catatcagcc ggagaggaaa   2400

gactgacact gggagtggct ggccctgctg gccctgcctc ttctggcctg gtgtctcctc   2460

atgccccctc agtgaggatc ttcatgtacc tgctcttctg tttgcacacc cagcatagcc   2520

tccttgcagg cagaaggcag tagggcccct gcacactcag tttctctcgt tttccttagt   2580

tatcagtcct gtcctgtccc actcaggtct gtacttaggg cagctggcct ggatgggctt   2640

cactggggcc ctgtctgtgt gctgagccag tttcccctgc tggctgcaag ctgtgggttc   2700

tttctcctct gtgcccctca tgctgatctt ctagatgcca ctcccaaatc cccttcatac   2760

ccaccaggat gtgtgcccag ccaggcctcc agcaccccca gtgcagctcg tgattggaaa   2820

ctcaccatcg gcaggcagtg gttcggttta agagatggca ttagagggag cccagtctgg   2880

atgtggactt ggatgccctg tgggtatcag ttctgctgac actttggccc gaaatagatc   2940

cagtgctgag caagcaatgt acaccagagc ctcagtgagc ccatctgcac agtggggagc   3000

atggagggat gggtttggcc tgtgcttctg cttattcagt ccttcagctc acggaaggga   3060

tgctagtccg tgaaggtgac ctcacagtac tggttaatta aactttattg ctcactgtcc   3120

acttttgtgc tg                                                       3132


<210>  8595
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  8595

Met Asp Ala Trp Gly Arg Leu Glu Ala Arg His Lys Ser Tyr Leu His 
1               5                   10                  15


Ser Arg Arg Gly Asp His Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg 
            20                  25                  30


Phe Thr Ser Gln Thr His Ser His Trp Ala Lys Ser Ser Cys His Cys 
        35                  40                  45


Arg Phe Glu Ser Arg Pro Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr 
    50                  55                  60


Asn Arg Ser Trp Gly Gly Glu Ser Ala Glu Arg Thr Trp Met Lys Gln 
65                  70                  75                  80


Arg Gly Thr Cys Leu Ser His Ser Pro Leu Asp Leu Leu His Pro Gly 
                85                  90                  95


Leu Cys Gln His Lys Val Gly Ala Arg 
            100                 105


<210>  8596
<211>  3587
<212>  DNA
<213>  Homo sapiens

<400>  8596
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa gatcacggga attacaagtg acatcctgaa gtatgatcac   1860

aaatgtttca aattaagcct tcctgctaag tttccagagg tgtgtggctc ggacgaagtg   1920

tttccagacc ctgatctact gcatgtcctg cctgttgctg gttctttgca gcagtccatt   1980

gaccaatgct gtctacagct tgagagcctc tgcaggccag ggctgctctg tgcacatcct   2040

acgttactat tcaaactgca cagcagcatg aaaaacaggc ccttcttttc tctcatttac   2100

acatatgtga agaagacaca gcaagtgaga aaacgtgacc gaaagccacg cggacaggtg   2160

gccgcagggc caaacccaac ttccgtgatg tgatctggct acagtttgga gcccacatat   2220

ttcaatagtt atccccaggc ctggcacgtc aaagaggctc cagaaatgtt tgctgagtta   2280

gaagcaaggc acaagtcata cctacattca aggagagggg accatgcaaa ggataaactg   2340

cagagagaca acagatttac atcccagaca cattcacact gggccaagag cagctgccat   2400

tgcagattcg agtcacgtcc ttttttcctt ccttctcctt cttggagtta caacagaagc   2460

tggggaggtg agagtgcaga aaggacgtgg atgaagcaga gaggcacgtg cctgtctcat   2520

tcgcctctgg atctgctgca tccaggactg tgccagcaca aagtgggagc ccgataaata   2580

tttattgaag aaatgaaagg tgacaaaagg cagaaggagg gagaccccaa aaagagtatg   2640

aacccagcat cacagtgcac ttgtggcaga tggcagtgca tacccgggag ctactctcct   2700

ccggccagat gcccttctcc cagctgcccg ccgtgtggca gctctacccc gggaggaagt   2760

accgagcagc ggattccagt ttctgggaaa tagcagacca tggccagatt gactctatgg   2820

agcagctggt cctaacatat cagccggaga ggaaagactg acactgggag tggctggccc   2880

tgctggccct gcctcttctg gcctggtgtc tcctcatgcc ccctcagtga ggatcttcat   2940

gtacctgctc ttctgtttgc acacccagca tagcctcctt gcaggcagaa ggcagtaggg   3000

cccctgcaca ctcagtttct ctcgttttcc ttagttatca gtcctgtcct gtcccactca   3060

ggtctgtact tagggcagct ggcctggatg ggcttcactg gggccctgtc tgtgtgctga   3120

gccagtttcc cctgctggct gcaagctgtg ggttctttct cctctgtgcc cctcatgctg   3180

atcttctaga tgccactccc aaatcccctt catacccacc aggatgtgtg cccagccagg   3240

cctccagcac ccccagtgca gctcgtgatt ggaaactcac catcggcagg cagtggttcg   3300

gtttaagaga tggcattaga gggagcccag tctggatgtg gacttggatg ccctgtgggt   3360

atcagttctg ctgacacttt ggcccgaaat agatccagtg ctgagcaagc aatgtacacc   3420

agagcctcag tgagcccatc tgcacagtgg ggagcatgga gggatgggtt tggcctgtgc   3480

ttctgcttat tcagtccttc agctcacgga agggatgcta gtccgtgaag gtgacctcac   3540

agtactggtt aattaaactt tattgctcac tgtccacttt tgtgctg                 3587


<210>  8597
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8597

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8598
<211>  3520
<212>  DNA
<213>  Homo sapiens

<400>  8598
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa gatcacggga attacaagtg acatcctgaa gtatgatcac   1860

aaatgtttca aattaagcct tcctgctaag tttccagagg tgtgtggctc ggacgaagtg   1920

tttccagacc ctgatctact gcatgtcctg cctgttgctg gttctttgca gcagtccatt   1980

gaccaatgct gtctacagct tgagagcctc tgcaggccag ggctgctctg tgcacatcct   2040

acgttactat tcaaactgca cagcagcatg aaaaacaggc ccttcttttc tctcatttac   2100

acatatgtga agaagacaca gcaagtgaga aaacgtgacc gaaagccacg cggacaggtg   2160

gccgcagggc caaacccaac ttccgtgatg tgatctggct acagtttgga gcccacatat   2220

ttcaatagtt atccccaggc ctggcacgtc aaagaggctc cagaaatgtt tgctgaagag   2280

acaacagatt tacatcccag acacattcac actgggccaa gagcagctgc cattgcagat   2340

tcgagtcacg tccttttttc cttccttctc cttcttggag ttacaacaga agctggggag   2400

gtgagagtgc agaaaggacg tggatgaagc agagaggcac gtgcctgtct cattcgcctc   2460

tggatctgct gcatccagga ctgtgccagc acaaagtggg agcccgataa atatttattg   2520

aagaaatgaa aggtgacaaa aggcagaagg agggagaccc caaaaagagt atgaacccag   2580

catcacagtg cacttgtggc agatggcagt gcatacccgg gagctactct cctccggcca   2640

gatgcccttc tcccagctgc ccgccgtgtg gcagctctac cccgggagga agtaccgagc   2700

agcggattcc agtttctggg aaatagcaga ccatggccag attgactcta tggagcagct   2760

ggtcctaaca tatcagccgg agaggaaaga ctgacactgg gagtggctgg ccctgctggc   2820

cctgcctctt ctggcctggt gtctcctcat gccccctcag tgaggatctt catgtacctg   2880

ctcttctgtt tgcacaccca gcatagcctc cttgcaggca gaaggcagta gggcccctgc   2940

acactcagtt tctctcgttt tccttagtta tcagtcctgt cctgtcccac tcaggtctgt   3000

acttagggca gctggcctgg atgggcttca ctggggccct gtctgtgtgc tgagccagtt   3060

tcccctgctg gctgcaagct gtgggttctt tctcctctgt gcccctcatg ctgatcttct   3120

agatgccact cccaaatccc cttcataccc accaggatgt gtgcccagcc aggcctccag   3180

cacccccagt gcagctcgtg attggaaact caccatcggc aggcagtggt tcggtttaag   3240

agatggcatt agagggagcc cagtctggat gtggacttgg atgccctgtg ggtatcagtt   3300

ctgctgacac tttggcccga aatagatcca gtgctgagca agcaatgtac accagagcct   3360

cagtgagccc atctgcacag tggggagcat ggagggatgg gtttggcctg tgcttctgct   3420

tattcagtcc ttcagctcac ggaagggatg ctagtccgtg aaggtgacct cacagtactg   3480

gttaattaaa ctttattgct cactgtccac ttttgtgctg                         3520


<210>  8599
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8599

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8600
<211>  3228
<212>  DNA
<213>  Homo sapiens

<400>  8600
acatgtcctt aaccttggca caacaaatct ctaaatcgat tgagacctgt ctcagatact     60

tcttggttta caagatggag gctgaaatta aagagaaaga tcctcactca actcacagag    120

gagcagaatg ggaagaggac ttagtgagaa ttccctgaac acaggagaaa accgaagccc    180

agagagtgga tggccaagtc caaggtcaca cagccaagtg catccgagca gcgcaggatc    240

caggtttcct gccccagtgc tctttctgca gcccatgcca cctgttttca tgctatctca    300

gttcaccttc cagctacaca cctgcaatca gaaacagaaa gtctgagagt gtgtgtggag    360

ccaaagaggg gacagcagtg gtgaggccag tttcatgtct tgtgatttat tttctccctt    420

tctttttgga ctttaatctt aagtggacag caatttggaa cagtgtcagc accttgttgg    480

attgtgctgt ttgggagagg tgacacagag tattttaaaa gagcaggtta agaacttttc    540

acaaggaatc aattgagaga aaataaaata gaaacagact gtcccacatt tgggctgagc    600

accaaacaca tttttttttt tttttttgag actgagtctt gctctgtcac tcaggctgga    660

atgcagtggc gcgatctcgg ctcactgcag ccttcacctc ccgggttcaa gtgattcttc    720

tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccatgcca ggctaatttt    780

tgtattttta gtagagacga ggtttcacca tgttggccag gctggtcttg aactcctgac    840

caagtgatcc acctgcttcg gcctcccaaa gtgctgggat tacaggcacg agccaccgca    900

cctggcctca aacaagcttt ttaattgcat tcagaagtgc accaactagg cacagacctc    960

tggcatggag acagaatggg aggttcttgg tgtctggcct ggtcttgcag aaatcaggga   1020

gttgtgggga ccaggcagcc actgtgcatc agataggagt ttcagcagca ggcaacagaa   1080

agcctgccaa tgtagctgaa ataagaaggg cttattttta tccctgaaca gaagcttcca   1140

gcactggttc atcagatcag ggcactgagc tggcatcccc atttatacag ttttcctttc   1200

cttcaccttt gtaagatgcc tggcacagct ctgagcatca aatatctgtg ccatgtggga   1260

gcacacgagg ggacaagtgg ggaatagggt ctcctctgtc ctctgtcccc aggctggctt   1320

ctctcgtggt agaaggaccc ccacagcacc aggcctcata actaccctgc tggtaaactg   1380

caggtgctgt cacggcttcc tgccttcgta tatgaaatgt tccttggcag ctggactgct   1440

gtttgtttac cgcacgcaca gctctgctgc ctcttggtta caccagtgag ctattgctcc   1500

atgacaagcc acaccgaaat gtagcaagca cttattgttg cccacatgtg tcaagtcagt   1560

tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt ggctgagctt gctctggtgc   1620

tagggtcagc tagacaggtc ggcaggagac cagctgctct agaagagcct ggacaggatg   1680

aattggttct ccttccacgt gcatcttgca tccctccagc caaggatttg aacccaggtc   1740

tcgtctgact ccaaatgcac caagaggatg gagcccagag tgacacagag gaagaggccc   1800

ctggatggat gcatggggaa ggttagaagc aaggcacaag tcatacctac attcaaggag   1860

aggggaccat gcaaaggata aactgcagag agacaacaga tttacatccc agacacattc   1920

acactgggcc aagagcagct gccattgcag attcgagtca cgtccttttt tccttccttc   1980

tccttcttgg agttacaaca gaagctgggg aggtgagagt gcagaaagga cgtggatgaa   2040

gcagagaggc acgtgcctgt ctcattcgcc tctggatctg ctgcatccag gactgtgcca   2100

gcacaaagtg ggagcccgat aaatatttat tgaagaaatg aaaggtgaca aaaggcagaa   2160

ggagggagac cccaaaaaga ggagagacaa agtttaatca tgtgggccag gctggttttg   2220

aactcctgac ctcaagtgat ctgcccacct tggcctccca aagtgctggg attacagtat   2280

gaacccagca tcacagtgca cttgtggcag atggcagtgc atacccggga gctactctcc   2340

tccggccaga tgcccttctc ccagctgccc gccgtgtggc agctctaccc cgggaggaag   2400

taccgagcag cggattccag tttctgggaa atagcagacc atggccagat tgactctatg   2460

gagcagctgg tcctaacata tcagccggag aggaaagact gacactggga gtggctggcc   2520

ctgctggccc tgcctcttct ggcctggtgt ctcctcatgc cccctcagtg aggatcttca   2580

tgtacctgct cttctgtttg cacacccagc atagcctcct tgcaggcaga aggcagtagg   2640

gcccctgcac actcagtttc tctcgttttc cttagttatc agtcctgtcc tgtcccactc   2700

aggtctgtac ttagggcagc tggcctggat gggcttcact ggggccctgt ctgtgtgctg   2760

agccagtttc ccctgctggc tgcaagctgt gggttctttc tcctctgtgc ccctcatgct   2820

gatcttctag atgccactcc caaatcccct tcatacccac caggatgtgt gcccagccag   2880

gcctccagca cccccagtgc agctcgtgat tggaaactca ccatcggcag gcagtggttc   2940

ggtttaagag atggcattag agggagccca gtctggatgt ggacttggat gccctgtggg   3000

tatcagttct gctgacactt tggcccgaaa tagatccagt gctgagcaag caatgtacac   3060

cagagcctca gtgagcccat ctgcacagtg gggagcatgg agggatgggt ttggcctgtg   3120

cttctgctta ttcagtcctt cagctcacgg aagggatgct agtccgtgaa ggtgacctca   3180

cagtactggt taattaaact ttattgctca ctgtccactt ttgtgctg                3228


<210>  8601
<211>  105
<212>  PRT
<213>  Homo sapiens

<400>  8601

Met Asp Ala Trp Gly Arg Leu Glu Ala Arg His Lys Ser Tyr Leu His 
1               5                   10                  15


Ser Arg Arg Gly Asp His Ala Lys Asp Lys Leu Gln Arg Asp Asn Arg 
            20                  25                  30


Phe Thr Ser Gln Thr His Ser His Trp Ala Lys Ser Ser Cys His Cys 
        35                  40                  45


Arg Phe Glu Ser Arg Pro Phe Phe Leu Pro Ser Pro Ser Trp Ser Tyr 
    50                  55                  60


Asn Arg Ser Trp Gly Gly Glu Ser Ala Glu Arg Thr Trp Met Lys Gln 
65                  70                  75                  80


Arg Gly Thr Cys Leu Ser His Ser Pro Leu Asp Leu Leu His Pro Gly 
                85                  90                  95


Leu Cys Gln His Lys Val Gly Ala Arg 
            100                 105


<210>  8602
<211>  605
<212>  DNA
<213>  Homo sapiens

<400>  8602
agatggaggc tgaaattaaa gagaaagatc ctcactcaac tcatgctatc tcagttcacc     60

ttccagctac acacctgcaa tcagaaacag aaagtctgag agtgtgtgtg cagagagaca    120

acagatttac atcccagaca cattcacact gggccaagag cagctgccat tgcagattcg    180

agtcacgtcc ttttttcctt ccttctcctt cttggagtta caacagaagc tggggaggtg    240

agagtgcaga aggagggaga ccccaaaaag aggtaaattt ggtatcttag caagtgggtg    300

actaccactg tctgggggaa agctgataca cgaggacttg acaataatta cagcagtaac    360

aatcgctact attttgtttt gagatgaatt ttagtttctg aaattgtcca aagcactttt    420

atcaatagaa acttgttaca catccctcca acagggagaa gcagcacagg aagctgcccc    480

ctcaaacact aaaggctcct ggagctattc acagtgctgg ggaacaacca gaggaggagg    540

aggacagagg gagagaatac tttttttaaa aatcccaaac aaaaccaaat tctatacatg    600

tatat                                                                605


<210>  8603
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  8603

Met Glu Ala Glu Ile Lys Glu Lys Asp Pro His Ser Thr His Ala Ile 
1               5                   10                  15


Ser Val His Leu Pro Ala Thr His Leu Gln Ser Glu Thr Glu Ser Leu 
            20                  25                  30


Arg Val Cys Val Gln Arg Asp Asn Arg Phe Thr Ser Gln Thr His Ser 
        35                  40                  45


His Trp Ala Lys Ser Ser Cys His Cys Arg Phe Glu Ser Arg Pro Phe 
    50                  55                  60


Phe Leu Pro Ser Pro Ser Trp Ser Tyr Asn Arg Ser Trp Gly Gly Glu 
65                  70                  75                  80


Ser Ala Glu Gly Gly Arg Pro Gln Lys Glu Val Asn Leu Val Ser 
                85                  90                  95


<210>  8604
<211>  2692
<212>  DNA
<213>  Homo sapiens

<400>  8604
tccttggcag ctggactgct gtttgtttac cgcacgcaca gctctgctgc ctcttggtta     60

caccagtgag ctattgctcc atgacaagcc acaccgaaat gtagcaagca cttattgttg    120

cccacatgtg tcaagtcagt tgagtgtttc tgccaaccgg ggcctggctt ggcccacctt    180

ggctgagctt gctctggtgc tagggtcagc tagacaggtc ggcaggagac cagctgctct    240

agaagagcct ggacaggatg aattggttct ccttccacgt gcatcttgca tccctccagc    300

caaggatttg aacccaggtc tcgtctgact ccaaatgcac caagaggatg gagcccagag    360

tgacacagag gaagaggccc ctggatggat gcatggggaa gatcacggga attacaagtg    420

acatcctgaa gtatgatcac aaatgtttca aattaagcct tcctgctaag tttccagagg    480

tgtgtggctc ggacgaagtg tttccagacc ctgatctact gcatgtcctg cctgttgctg    540

gttctttgca gcagtccatt gaccaatgct gtctacagct tgagagcctc tgcaggccag    600

ggctgctctg tgcacatcct acgttactat tcaaactgca cagcagcatg aaaaacaggc    660

ccttcttttc tctcatttac acatatgtga agaagacaca gcaagtgaga aaacgtgacc    720

gaaagccacg cggacaggtg gccgcagggc caaacccaac ttccgtgatg tgatctggct    780

acagtttgga gcccacatat ttcaatagtt atccccaggc ctggcacgtc aaagaggctc    840

cagaaatgtt tgctgagtga gtgatgaatc agcaatttct gattttctcc taaacttaga    900

gaataagtgg cttgtctgca gtcacccagg gcgtccctga cagaggtaca agtaaagccc    960

agatctctgc atctctggtt caaggccttt tgtactacac accgctgtct ctttgtcatc   1020

attaaaagca aggctcaagg gacatgtttt ctagccttag ttccccatct acaaaatggg   1080

cctcatggaa tggaatgtct ccacttcact ccagcatcaa caagtgggga attctgatgg   1140

attcaattcg acttctttcc atgggcgtgt tctaagcagc ctctttgttc cagaagctgc   1200

cctcagccag agttggataa gccaatcctc actccccagc ctcctctgga tagggatgaa   1260

gaccccactg gggttggaag tgcagaggca gacaggtgta tggagtcacc tgtaaattga   1320

ttcaagtgag ccaggaaagc agcaaaggaa agagaaacct gagtgacgac gtggtggagg   1380

aacagggctg gaaagaggct gctggctgtc tggcttcgca gctctggcct cctaatcagc   1440

ctcgctcttg tctctggtgt tctctggctc ttgtccatct gtctgtgttt ctttttgcca   1500

gctattgact aatctttgct gaagctgagc tagaattctg gtgtttataa gcaggtaact   1560

agctgagcac tagttgataa ctttggagtt agtggataac cacagggctg ggctactaag   1620

ctttttcagt tgaaaaataa ataaataaat aaataaacac cacacccagc taatttttgt   1680

atttttagta gagacagggt ttcaccgtgt tagccaggat ggactccatc tcctgacctc   1740

gtgatccgcc tacctcggcc tcccaaagtg ctgggattac aggcgtgagc caccacgccc   1800

ggtcaccttt gtcctgtttt ctacaggtta gaagcaaggc acaagtcata cctacattca   1860

aggagagggg accatgcaaa ggataaactg caggtgaaga acttgagagc tattttagaa   1920

gctgccttcc acactttaca atctactttg cagctatact gagctcttag caactccctg   1980

ggcctgctga gcacctcttg cctttctgcc tttgcgtatg ctgttccctc tgcctggaat   2040

tccatgtctt ctgcctttgc ccacctcatc ttaaggcctc tgcttagatg caatttcttt   2100

gggctcttat tagcagcatc caaatctgtg ctggtttctt ctcacgctta ctctgcatca   2160

taatttttct gtttactcgt taatcccctc ccactcctgc cagtacctaa agtaaaatct   2220

acacgggctt ggcacattgt ggatgctcaa tgaagatttg ttaaatgagt gaatgattaa   2280

atgaaataag ccccagcttg gaacccagag ctgtaatttc cggttgtggt ccctgtcccc   2340

tgcccagggg ctgtctaagg gctcatctct cccaggagcc cctgtatcat ctcagtaact   2400

agaccagtac catatccgac ttcccctgac tttgaaataa ttttcacctg caatcaggtg   2460

cgcttcccta gaacctctct cgctgttctt tgcctttctc cttcccccgc cttgtatctc   2520

cgtggtcctg ccaaaaatca gaagctcatt attaaaccag aagcttcctt gcattatccc   2580

agagactaca gacagaaaat atttgcttct atctcaactg aggactgaca tagtaaagac   2640

tccttgagat gttagctgtc aaggagggga ataaaagttt ttcatctgca tg           2692


<210>  8605
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8605

Met Glu Pro Arg Val Thr Gln Arg Lys Arg Pro Leu Asp Gly Cys Met 
1               5                   10                  15


Gly Lys Ile Thr Gly Ile Thr Ser Asp Ile Leu Lys Tyr Asp His Lys 
            20                  25                  30


Cys Phe Lys Leu Ser Leu Pro Ala Lys Phe Pro Glu Val Cys Gly Ser 
        35                  40                  45


Asp Glu Val Phe Pro Asp Pro Asp Leu Leu His Val Leu Pro Val Ala 
    50                  55                  60


Gly Ser Leu Gln Gln Ser Ile Asp Gln Cys Cys Leu Gln Leu Glu Ser 
65                  70                  75                  80


Leu Cys Arg Pro Gly Leu Leu Cys Ala His Pro Thr Leu Leu Phe Lys 
                85                  90                  95


Leu His Ser Ser Met Lys Asn Arg Pro Phe Phe Ser Leu Ile Tyr Thr 
            100                 105                 110


Tyr Val Lys Lys Thr Gln Gln Val Arg Lys Arg Asp Arg Lys Pro Arg 
        115                 120                 125


Gly Gln Val Ala Ala Gly Pro Asn Pro Thr Ser Val Met 
    130                 135                 140


<210>  8606
<211>  2078
<212>  DNA
<213>  Homo sapiens

<400>  8606
ctcccaaagt gctgggatta caggcgtgag ccaccacgcc cggtcacctt tgtcctgttt     60

tctacaggtt agaagcaagg cacaagtcat acctacattc aaggagaggg gaccatgcaa    120

aggataaact gcagagagac aacagattta catcccagac acattcacac tgggccaaga    180

gcagctgcca ttgcagattc gagtcacgtc cttttttcct tccttctcct tcttggagtt    240

acaacagaag ctggggaggt gagagtgcag aaaggacgtg gatgaagcag agaggcacgt    300

gcctgtctca ttcgcctctg gatctgctgc atccaggact gtgccagcac aaagtgggag    360

cccgataaat atttattgaa gaaatgaaag gtgacaaaag gcagaaggag ggagacccca    420

aaaagagacc ccaggctcca gaagcagatg aggagacaaa cagaagagca gaagaatggc    480

agaatggcac agcagagaga agaaaaggaa catctgaatg ttgagaggaa tttggctggg    540

ggcggttgga gaggagatta gccactggac agccaaactc caggggaaga tcatcttccc    600

actccatccc ccttccagct ccccatccat cctgctgaga gccacctcca ccactcagtg    660

aaaccgctgc attcatcctt caagtttatg tgtgacctga ttcttcctgg acattggaca    720

aagacctagg tccagtgaac tgtctaacac ttaagtcatc cacggacagc aaggctaaca    780

gaacgctgta acatgtgccc acttggactc tgggagttgc agacacccac ccataggtgc    840

tgccatgggt ccggagccca aaaagtgctt gccctggctc ctgcacctgc ccgtctgcat    900

gctccccctc cggtaagggg tttgaggatg tggcggctga acataagagc tatgcccctg    960

tcacacatca tgggacaggg gtcagggaac tctcccattt cactttcaaa tattccaggt   1020

cccctttttg ttcgggagcc agagtctaat ggagacagag atagaaaccc tgaaatagga   1080

tccaggcaat ataaacctac acgctgtaag ccaagtcaga gtgaggctga tgtgataaca   1140

aaagtctgaa tacaaggtgg gagacaatta ttctgactga aagggaggca agagttctgc   1200

cataggcttg atgctgtgtg cccctggctt cctaactcat ttgcaaatgg aaaatactat   1260

tccattgtag gaaccttctt tttccatgtg tctggggaag gagaaagaat ggctgggctg   1320

aatgaattta tcccttggtc ctcttccaac aaagctcagc tatgaaagat aaatccagct   1380

ctccccaccc cctctcagtg gagctgggga gaaatcaaaa gcccctctgc caataatgag   1440

accaaagttt gcaagggcag gacgagcccg tgctaacaga gaaagtgttg tttcctcaat   1500

ttggttttag actgtcttgt cctatggggg agaaaagatc tgcccttggg agaggtgcca   1560

actttataga tctattaata aaagaactgg caggcttaca gttcttgcca atgaggaaac   1620

ttgaatgaga gaagccaggc tcaaccttgg ccaacagact ggagcccatc accctaactt   1680

caccccgctt ctccttaccc aaccgtcaaa ggctaggcag cacccaccca gcagcttcca   1740

cctggctgaa gcctgcacct gcttcagacc aagggttaga tggaaatttg gcatgggaag   1800

agagggctca cctgtgggca ggatagactc tatccaagaa ggagaactga aaaatgaaaa   1860

cctatgagac aaggggtgat cctgaaggca ggcaggagaa agggctggag ggagaggcac   1920

tggggaattt ttcctggtga atactgaagt tactagatgt tttgtcttgc aaaactcaag   1980

ggaaaactct caaactctaa tgtttgtcta ttctgtgtcc aaactgtcct tttgaaacgg   2040

acccaccttt cagtaaagaa acttgcattg gcctgccc                           2078


<210>  8607
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  8607

Met Gln Arg Ile Asn Cys Arg Glu Thr Thr Asp Leu His Pro Arg His 
1               5                   10                  15


Ile His Thr Gly Pro Arg Ala Ala Ala Ile Ala Asp Ser Ser His Val 
            20                  25                  30


Leu Phe Ser Phe Leu Leu Leu Leu Gly Val Thr Thr Glu Ala Gly Glu 
        35                  40                  45


Val Arg Val Gln Lys Gly Arg Gly 
    50                  55


<210>  8608
<211>  2290
<212>  DNA
<213>  Homo sapiens

<400>  8608
ctcccaaagt gctgggatta caggcgtgag ccaccacgcc cggtcacctt tgtcctgttt     60

tctacaggtt agaagcaagg cacaagtcat acctacattc aaggagaggg gaccatgcaa    120

aggataaact gcagagagac aacagattta catcccagac acattcacac tgggccaaga    180

gcagctgcca ttgcagattc gagtcacgtc cttttttcct tccttctcct tcttggagtt    240

acaacagaag ctggggaggt gagagtgcag aaaggacgtg gatgaagcag agaggcacgt    300

gcctgtctca ttcgcctctg gatctgctgc atccaggact gtgccagcac aaagtgggag    360

cccgataaat atttattgaa gaaatgaaag gtgacaaaag gcagaaggag ggagacccca    420

aaaagagacc ccaggctcca gaagcagatg aggagacaaa cagaagagca gaagaatggc    480

agaatggcac agcagagaga agaaaaggaa catctgaatg ttgagaggaa tttggctggg    540

ggcggttgga gaggagatta gccactggac agccaaactc caggggaaga tcatcttccc    600

actccatccc ccttccagct ccccatccat cctgctgaga gccacctcca ccactcagtg    660

aaaccgctgc attcatcctt caagtttatg tgtgacctga ttcttcctgg acattggaca    720

aagacctagg tccagtgaac tgtctaacac ttaagtcatc cacggacagc aaggctaaca    780

gaacgctgta acatgtgccc acttggactc tgggagttgc agacacccac ccataggtgc    840

tgccatgggt ccggagccca aaaagtgctt gccctggctc ctgcacctgc ccgtctgcat    900

gctccccctc cggtaagggg tttgaggatg tggcggctga acataagagc tatgcccctg    960

tcacacatca tgggacaggg gtcagggaac tctcccattt cactttcaaa tattccaggt   1020

cccctttttg ttcgggagcc agagtctaat ggagacagag atagaaaccc tgaaatagga   1080

tccaggcaat ataaacctac acgctgtaag ccaagtcaga gtgaggctga tgtgataaca   1140

aaagtctgaa tacaaggtgg gagacaatta ttctgactga aagggaggca agagttctgc   1200

cataggcttg atgctgtgtg cccctggctt cctaactcat ttgcaaatgg aaaatactat   1260

tccattgtag gaaccttctt tttccatgtg tctggggaag gagaaagaat ggctgggctg   1320

aatgaattta tcccttggtc ctcttccaac aaagctcagc tatgaaagat aaatccagct   1380

ctccccaccc cctctcagtg gagctgggga gaaatcaaaa gcccctctgc caataatgag   1440

accaaagttt gcaagggcag gacgagcccg tgctaacaga gaaagtgttg tttcctcaat   1500

ttggttttag actgtcttgt cctatggggg agaaaagatc tgcccttggg agaggtgcca   1560

actttataga tctattaata aaagaactgg caggcttaca gttcttgcca atgaggaaac   1620

ttgaatgaga gaagccaggc tcaaccttgg ccaacagact ggagcccatc accctaactt   1680

caccccgctt ctccttaccc aaccgtcaaa ggctaggcag cacccaccca gcagcttcca   1740

cctggctgaa gcctgcacct gcttcagacc aagggttaga tggaaatttg gcatgggaag   1800

agagggctca cctgtgggca ggatagactc tatccaagaa ggagaactga aaaatgaaaa   1860

cctatgagac aaggggtgat cctgaaggca ggcaggagaa agggctggag ggagaggcac   1920

tggggaattt ttcctggtga atactgaagt tactagatgt tttgtcttgc aaaactcaag   1980

ggaaaactct caaactctaa tgtttgtcta ttctgtgtcc aaactgtcct tttgaaacgg   2040

acccaccttt cagtaaagaa acttgcattg gcctgcccag cctggtgtgt tagttctgtg   2100

gaaactgact ggctagggtg gccacgggag gaagagcctg gttctccctc accagctcct   2160

tgtgaagaag ggacctggtc aataaggcaa acgacaccac ttgccaacat ttgatattgc   2220

caagtgcttt tgtttggcac tactatagat tttaaaaatg tatctcactt ttaaaatttg   2280

cattttcttg                                                          2290


<210>  8609
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  8609

Met Gln Arg Ile Asn Cys Arg Glu Thr Thr Asp Leu His Pro Arg His 
1               5                   10                  15


Ile His Thr Gly Pro Arg Ala Ala Ala Ile Ala Asp Ser Ser His Val 
            20                  25                  30


Leu Phe Ser Phe Leu Leu Leu Leu Gly Val Thr Thr Glu Ala Gly Glu 
        35                  40                  45


Val Arg Val Gln Lys Gly Arg Gly 
    50                  55


<210>  8610
<211>  1164
<212>  DNA
<213>  Homo sapiens

<400>  8610
tggaaagcta cacgtgtgag cctagaggcg ggtcccggtt gcagacttgc catggcctcc     60

gaagcttctg tgcgtctagg ggtgccccct ggccgtctgt ggatccagag gcctggcatc    120

tacgaagatg aggaggggag aacctgggtg actgtggtcg tgcggttcaa tccctcgcgt    180

agggaatggg ccagggcctc ccagggcagc agatatgaac ccagcatcac agtgcacttg    240

tggcagatgg cagtgcatac ccgggagcta ctctcctccg gccagatgcc cttctcccag    300

ctgcccgccg tgtggcagct ctaccccggg aggaagtacc gagcagcgga ttccagtttc    360

tgggaaatag cagaccatgg ccagattgac tctatggagc agctggtcct aacatatcag    420

ccggagagga aagactgaca ctgggagtgg ctggccctgc tggccctgcc tcttctggcc    480

tggtgtctcc tcatgccccc tcagtgagga tcttcatgta cctgctcttc tgtttgcaca    540

cccagcatag cctccttgca ggcagaaggc agtagggccc ctgcacactc agtttctctc    600

gttttcctta gttatcagtc ctgtcctgtc ccactcaggt ctgtacttag ggcagctggc    660

ctggatgggc ttcactgggg ccctgtctgt gtgctgagcc agtttcccct gctggctgca    720

agctgtgggt tctttctcct ctgtgcccct catgctgatc ttctagatgc cactcccaaa    780

tccccttcat acccaccagg atgtgtgccc agccaggcct ccagcacccc cagtgcagct    840

cgtgattgga aactcaccat cggcaggcag tggttcggtt taagagatgg cattagaggg    900

agcccagtct ggatgtggac ttggatgccc tgtgggtatc agttctgctg acactttggc    960

ccgaaataga tccagtgctg agcaagcaat gtacaccaga gcctcagtga gcccatctgc   1020

acagtgggga gcatggaggg atgggtttgg cctgtgcttc tgcttattca gtccttcagc   1080

tcacggaagg gatgctagtc cgtgaaggtg acctcacagt actggttaat taaactttat   1140

tgctcactgt ccacttttgt gctg                                          1164


<210>  8611
<211>  128
<212>  PRT
<213>  Homo sapiens

<400>  8611

Met Ala Ser Glu Ala Ser Val Arg Leu Gly Val Pro Pro Gly Arg Leu 
1               5                   10                  15


Trp Ile Gln Arg Pro Gly Ile Tyr Glu Asp Glu Glu Gly Arg Thr Trp 
            20                  25                  30


Val Thr Val Val Val Arg Phe Asn Pro Ser Arg Arg Glu Trp Ala Arg 
        35                  40                  45


Ala Ser Gln Gly Ser Arg Tyr Glu Pro Ser Ile Thr Val His Leu Trp 
    50                  55                  60


Gln Met Ala Val His Thr Arg Glu Leu Leu Ser Ser Gly Gln Met Pro 
65                  70                  75                  80


Phe Ser Gln Leu Pro Ala Val Trp Gln Leu Tyr Pro Gly Arg Lys Tyr 
                85                  90                  95


Arg Ala Ala Asp Ser Ser Phe Trp Glu Ile Ala Asp His Gly Gln Ile 
            100                 105                 110


Asp Ser Met Glu Gln Leu Val Leu Thr Tyr Gln Pro Glu Arg Lys Asp 
        115                 120                 125


<210>  8612
<211>  1628
<212>  DNA
<213>  Homo sapiens

<400>  8612
acacgtgtga gcctagaggc gggtcccggt tgcagacttg ccatggcctc cgaagcttct     60

gtgcgtctag gggtgccccc tggccgtctg tggatccaga ggcctggcat ctacgaagat    120

gaggagggga gaacctgggt gactgtggtc gtgcggttca atccctcgcg tagggaatgg    180

gccagggcct cccagggcag cagatatgaa cccagcatca cagtgcactt gtggcagatg    240

gcagtgcata cccgggagct actctcctcc ggccagatgc ccttctccca gctgcccgcc    300

gtgtggcagc tctaccccgg gaggaagtac cgagcagcgg attccagttt ctgggaaata    360

gcagaccatg gccagattga ctctatggag cagctggtcc taacatatca gccggagagg    420

aaagactgac actgggagtg gctggtatgt tggggccctg tgcgtctcag tgtagggatc    480

agacgaaagt gagaagacct ctcctctttt cagaaagacg gcgtggcctc ctcctccctg    540

ctgtttgctg agatttttct tacatagcca cctgtcacct ctgttcccca gccccttgga    600

tgtgatggta cacagtgggt gggcccccat aataagttcc taaagcatgg gatctcatcg    660

aataagactc atgaatctag tgatctcggg tccctagatt taaccatggc actgaggtgc    720

cgtgtgacgg tggccttgga ggacccagca ctgacccata gagggctcct ctcagatggg    780

cagcagcttg gagcaggcca ggcagggcct gggccattgg aggggctggc actggacttg    840

cctttgaccc cagcagcttg gatggggtgc cgggctcccc catagttcac tgactgtctc    900

ctttggtctt ctcgcaggcc ctgctggccc tgcctcttct ggcctggtgt ctcctcatgc    960

cccctcagtg aggatcttca tgtacctgct cttctgtttg cacacccagc atagcctcct   1020

tgcaggcaga aggcagtagg gcccctgcac actcagtttc tctcgttttc cttagttatc   1080

agtcctgtcc tgtcccactc aggtctgtac ttagggcagc tggcctggat gggcttcact   1140

ggggccctgt ctgtgtgctg agccagtttc ccctgctggc tgcaagctgt gggttctttc   1200

tcctctgtgc ccctcatgct gatcttctag atgccactcc caaatcccct tcatacccac   1260

caggatgtgt gcccagccag gcctccagca cccccagtgc agctcgtgat tggaaactca   1320

ccatcggcag gcagtggttc ggtttaagag atggcattag agggagccca gtctggatgt   1380

ggacttggat gccctgtggg tatcagttct gctgacactt tggcccgaaa tagatccagt   1440

gctgagcaag caatgtacac cagagcctca gtgagcccat ctgcacagtg gggagcatgg   1500

agggatgggt ttggcctgtg cttctgctta ttcagtcctt cagctcacgg aagggatgct   1560

agtccgtgaa ggtgacctca cagtactggt taattaaact ttattgctca ctgtccactt   1620

ttgtgctg                                                            1628


<210>  8613
<211>  128
<212>  PRT
<213>  Homo sapiens

<400>  8613

Met Ala Ser Glu Ala Ser Val Arg Leu Gly Val Pro Pro Gly Arg Leu 
1               5                   10                  15


Trp Ile Gln Arg Pro Gly Ile Tyr Glu Asp Glu Glu Gly Arg Thr Trp 
            20                  25                  30


Val Thr Val Val Val Arg Phe Asn Pro Ser Arg Arg Glu Trp Ala Arg 
        35                  40                  45


Ala Ser Gln Gly Ser Arg Tyr Glu Pro Ser Ile Thr Val His Leu Trp 
    50                  55                  60


Gln Met Ala Val His Thr Arg Glu Leu Leu Ser Ser Gly Gln Met Pro 
65                  70                  75                  80


Phe Ser Gln Leu Pro Ala Val Trp Gln Leu Tyr Pro Gly Arg Lys Tyr 
                85                  90                  95


Arg Ala Ala Asp Ser Ser Phe Trp Glu Ile Ala Asp His Gly Gln Ile 
            100                 105                 110


Asp Ser Met Glu Gln Leu Val Leu Thr Tyr Gln Pro Glu Arg Lys Asp 
        115                 120                 125


<210>  8614
<211>  356
<212>  DNA
<213>  Homo sapiens

<400>  8614
tcaaacaaaa caaagcaaaa caaaaaaaac agttaagatt tttttttttt ttaaatgatt     60

cagtggaaat agaatggatt cttcaaataa cttagccacg ggtgggataa gggacctact    120

tatatgaacc cagcatcaca gtgcacttgt ggcagatggc agtgcatacc cgggagctac    180

tctcctccgg ccagatgccc ttctcccagc tgcccgccgt gtggcagctc taccccggga    240

ggaagtaccg agcagcggat tccagtttct gggaaatagc agaccatggc cagattgact    300

ctatggagca gctggtccta acatatcagc cggagaggaa agactgacac tgggag        356


<210>  8615
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8615

Met Ala Val His Thr Arg Glu Leu Leu Ser Ser Gly Gln Met Pro Phe 
1               5                   10                  15


Ser Gln Leu Pro Ala Val Trp Gln Leu Tyr Pro Gly Arg Lys Tyr Arg 
            20                  25                  30


Ala Ala Asp Ser Ser Phe Trp Glu Ile Ala Asp His Gly Gln Ile Asp 
        35                  40                  45


Ser Met Glu Gln Leu Val Leu Thr Tyr Gln Pro Glu Arg Lys Asp 
    50                  55                  60


<210>  8616
<211>  1398
<212>  DNA
<213>  Homo sapiens

<400>  8616
gccgtcctcc cgccccgccg cttggtggcg gccgcatgct gcccggatat aaagggtcgg     60

ccccacatcc cagggaccag cgagcggcct tgagaggctc tggctcttgc ttcttaggcg    120

gcccgaggac gccatggccg agtgcccgac actcggggag gcagtcaccg accacccgga    180

ccgcctgtgg gcctgggaga agttcgtgta tttggacgag aagcagcacg cctggctgcc    240

cttaaccatc gagataaagg ataggttaca gttacgggtg ctcttgcgtc gggaagacgt    300

cgtcctgggg aggcctatga cccccaccca gataggccca agcctgctgc ctatcatgtg    360

gcagctctac cctgatggac gataccgatc ctcagactcc agtttctggc gcttagtgta    420

ccacatcaag attgacggcg tggaggacat gcttctcgag ctgctgccag atgactgatg    480

tatggtcttg gcagcacctg tctcctttca ccccagggcc tgagcctggc cagcctacaa    540

tggggatgtt gtgtttctgt tcaccttcgt ttactatgcc tgtgtcttct ccaccacgct    600

ggggtctggg aggaatggac agacagagga tgagctctac ccagggcctg caggacctgc    660

ctgtagccca ctctgctcgc cttagcacta ccactcctgc caaggaggat tccatttggc    720

agagcttctt ccaggtgccc agctatacct gtgcctcggc ttttctcagc tggatgatgg    780

tcttcagcct ctttctgtcc cttctgtccc tcacagcact agtatttcat gttgcacacc    840

cactcagctc cgtgaacttg tgagaacaca gccgattcac ctgagcagga cctctgaaac    900

cctggaccag tggtctcaca tggtgctacg cctgcatgta aacacgcctg caaacgctgc    960

ctgccggtaa acacgcctgc aaacgctgcc tgcccgtaaa cacgcctgca aacgctgcct   1020

gcccacacag gttcacgtgc agctcaagga aaggcctgaa aggagccctt atctgtgctc   1080

aggactcaga agcctctggg tcagtggtcc acatcccggg acgcagcagg aggccaggcc   1140

ggcgagccct gtggatgagc cctcagaacc cttggcttgc ccacgtggaa aagggataga   1200

ggttgggttt cccccctttt atagatggtc acgcacctgg gtgttacaaa gttgtatgtg   1260

gcatgaatac tttttgtaat gattgattaa atgcaagata gtttatctaa cttcgtgcgg   1320

aatcagcttc tatccttgac ttagattctg gtggagagaa gtgagaatag gcagccccca   1380

aataaaaaat attcatgg                                                 1398


<210>  8617
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8617

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8618
<211>  1081
<212>  DNA
<213>  Homo sapiens

<400>  8618
gaaggctggt gggaggaggg gcagtctcca agagcccctg aaatcctcac acctgggttc     60

ctacctgctg tttccagcta ggggaaggcg caggagtgag gaatggaggg agtggagggc    120

tctggccgat caatgccttc tctctctctc tgcctctcag attgacggcg tggaggacat    180

gcttctcgag ctgctgccag atgactgatg tatggtcttg gcagcacctg tctcctttca    240

ccccagggcc tgagcctggc cagcctacaa tggggatgtt gtgtttctgt tcaccttcgt    300

ttactatgcc tgtgtcttct ccaccacgct ggggtctggg aggaatggac agacagagga    360

tgagctctac ccagggcctg caggacctgc ctgtagccca ctctgctcgc cttagcacta    420

ccactcctgc caaggaggat tccatttggc agagcttctt ccaggtgccc agctatacct    480

gtgcctcggc ttttctcagc tggatgatgg tcttcagcct ctttctgtcc cttctgtccc    540

tcacagcact agtatttcat gttgcacacc cactcagctc cgtgaacttg tgagaacaca    600

gccgattcac ctgagcagga cctctgaaac cctggaccag tggtctcaca tggtgctacg    660

cctgcatgta aacacgcctg caaacgctgc ctgccggtaa acacgcctgc aaacgctgcc    720

tgcccgtaaa cacgcctgca aacgctgcct gcccacacag gttcacgtgc agctcaagga    780

aaggcctgaa aggagccctt atctgtgctc aggactcaga agcctctggg tcagtggtcc    840

acatcccggg acgcagcagg aggccaggcc ggcgagccct gtggatgagc cctcagaacc    900

cttggcttgc ccacgtggaa aagggataga ggttgggttt cccccctttt atagatggtc    960

acgcacctgg gtgttacaaa gttgtatgtg gcatgaatac tttttgtaat gattgattaa   1020

atgcaagata gtttatctaa cttcgtgcgg aatcagcttc tatccttgac ttagattctg   1080

g                                                                   1081


<210>  8619
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8619

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8620
<211>  1141
<212>  DNA
<213>  Homo sapiens

<400>  8620
cgatcctcct gcctctgcct tccaaagcac tggaattaca agtataaagg ataggttaca     60

gttacgggtg ctcttgcgtc gggaagacgt cgtcctgggg aggcctatga cccccaccca    120

gataggccca agcctgctgc ctatcatgtg gcagctctac cctgatggac gataccgatc    180

ctcagactcc agtttctggc gcttagtgta ccacatcaag attgacggcg tggaggacat    240

gcttctcgag ctgctgccag atgactgatg tatggtcttg gcagcacctg tctcctttca    300

ccccagggcc tgagcctggc cagcctacaa tggggatgtt gtgtttctgt tcaccttcgt    360

ttactatgcc tgtgtcttct ccaccacgct ggggtctggg aggaatggac agacagagga    420

tgagctctac ccagggcctg caggacctgc ctgtagccca ctctgctcgc cttagcacta    480

ccactcctgc caaggaggat tccatttggc agagcttctt ccaggtgccc agctatacct    540

gtgcctcggc ttttctcagc tggatgatgg tcttcagcct ctttctgtcc cttctgtccc    600

tcacagcact agtatttcat gttgcacacc cactcagctc cgtgaacttg tgagaacaca    660

gccgattcac ctgagcagga cctctgaaac cctggaccag tggtctcaca tggtgctacg    720

cctgcatgta aacacgcctg caaacgctgc ctgccggtaa acacgcctgc aaacgctgcc    780

tgcccgtaaa cacgcctgca aacgctgcct gcccacacag gttcacgtgc agctcaagga    840

aaggcctgaa aggagccctt atctgtgctc aggactcaga agcctctggg tcagtggtcc    900

acatcccggg acgcagcagg aggccaggcc ggcgagccct gtggatgagc cctcagaacc    960

cttggcttgc ccacgtggaa aagggataga ggttgggttt cccccctttt atagatggtc   1020

acgcacctgg gtgttacaaa gttgtatgtg gcatgaatac tttttgtaat gattgattaa   1080

atgcaagata gtttatctaa cttcgtgcgg aatcagcttc tatccttgac ttagattctg   1140

g                                                                   1141


<210>  8621
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8621

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8622
<211>  1503
<212>  DNA
<213>  Homo sapiens

<400>  8622
gggaccagcg agcggccttg agaggctctg gctcttgctt cttaggcggc ccgaggacgc     60

catggccgag tgcccgacac tcggggaggc agtcaccgac cacccggacc gcctgtgggc    120

ctgggagaag ttcgtgtatt tggacgagaa gcagcacgcc tggctgccct taaccatcga    180

gatacagggt ctcgctctgt gacccaggct ggtcttaaac tcctggcctc aagcgatcct    240

cctgcctctg ccttccaaag cactggaatt acaagtgtga gccgctgcaa cccgccagaa    300

aaaagtgtgc ctttcatggc cctgtctggg tggctagaca cgtgtgtgtg ctggtggtcc    360

tggcccagcc agagtccctg agaggagcat gcatggccta aggaaataaa ggataggtta    420

cagttacggg tgctcttgcg tcgggaagac gtcgtcctgg ggaggcctat gacccccacc    480

cagataggcc caagcctgct gcctatcatg tggcagctct accctgatgg acgataccga    540

tcctcagact ccagtttctg gcgcttagtg taccacatca agattgacgg cgtggaggac    600

atgcttctcg agctgctgcc agatgactga tgtatggtct tggcagcacc tgtctccttt    660

caccccaggg cctgagcctg gccagcctac aatggggatg ttgtgtttct gttcaccttc    720

gtttactatg cctgtgtctt ctccaccacg ctggggtctg ggaggaatgg acagacagag    780

gatgagctct acccagggcc tgcaggacct gcctgtagcc cactctgctc gccttagcac    840

taccactcct gccaaggagg attccatttg gcagagcttc ttccaggtgc ccagctatac    900

ctgtgcctcg gcttttctca gctggatgat ggtcttcagc ctctttctgt cccttctgtc    960

cctcacagca ctagtatttc atgttgcaca cccactcagc tccgtgaact tgtgagaaca   1020

cagccgattc acctgagcag gacctctgaa accctggacc agtggtctca catggtgcta   1080

cgcctgcatg taaacacgcc tgcaaacgct gcctgccggt aaacacgcct gcaaacgctg   1140

cctgcccgta aacacgcctg caaacgctgc ctgcccacac aggttcacgt gcagctcaag   1200

gaaaggcctg aaaggagccc ttatctgtgc tcaggactca gaagcctctg ggtcagtggt   1260

ccacatcccg ggacgcagca ggaggccagg ccggcgagcc ctgtggatga gccctcagaa   1320

cccttggctt gcccacgtgg aaaagggata gaggttgggt ttcccccctt ttatagatgg   1380

tcacgcacct gggtgttaca aagttgtatg tggcatgaat actttttgta atgattgatt   1440

aaatgcaaga tagtttatct aacttcgtgc ggaatcagct tctatccttg acttagattc   1500

tgg                                                                 1503


<210>  8623
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8623

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8624
<211>  756
<212>  DNA
<213>  Homo sapiens

<400>  8624
ggcagcacct gtctcctttc accccagggc ctgagcctgg ccagcctaca atggggatga     60

atggacagac agaggatgag ctctacccag ggcctgcagg acctgcctgt agcccactct    120

gctcgcctta gcactaccac tcctgccaag gaggattcca tttggcagag cttcttccag    180

gtgcccagct atacctgtgc ctcggctttt ctcagctgga tgatggtctt cagcctcttt    240

ctgtcccttc tgtccctcac agcactagta tttcatgttg cacacccact cagctccgtg    300

aacttgtgag aacacagccg attcacctga gcaggacctc tgaaaccctg gaccagtggt    360

ctcacatggt gctacgcctg catgtaaaca cgcctgcaaa cgctgcctgc cggtaaacac    420

gcctgcaaac gctgcctgcc cgtaaacacg cctgcaaacg ctgcctgccc acacaggttc    480

acgtgcagct caaggaaagg cctgaaagga gcccttatct gtgctcagga ctcagaagcc    540

tctgggtcag tggtccacat cccgggacgc agcaggaggc caggccggcg agccctgtgg    600

atgagccctc agaacccttg gcttgcccac gtggaaaagg gatagaggtt gggtttcccc    660

ccttttatag atggtcacgc acctgggtgt tacaaagttg tatgtggcat gaatactttt    720

tgtaatgatt gattaaatgc aagatagttt atctaa                              756


<210>  8625
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  8625

Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
1               5                   10                  15


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
            20                  25                  30


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
        35                  40                  45


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
    50                  55                  60


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
65                  70                  75                  80


Asn Leu 



<210>  8626
<211>  896
<212>  DNA
<213>  Homo sapiens

<400>  8626
cagcgagcgg ccttgagagg ctctggctct tgcttcttag gcggcccgag gacgccatgg     60

ccgagtgccc gacactcggg gaggcagtca ccgaccaccc ggaccgcctg tgggcctggg    120

agaagttcgt gtatttggac gagaagcagc acgcctggct gcccttaacc atcgagataa    180

aggataggtt acagttacgg gtgctcttgc gtcgggaaga cgtcgtcctg gggaggccta    240

tgacccccac ccagataggc ccaagcctgc tgcctatcat gtggcagctc taccctgatg    300

gacgataccg atcctcagac tccagtttct ggcgcttagt gtaccacatc aagattgacg    360

gcgtggagga catgcttctc gagctgctgc cagatgactg atcactagta tttcatgttg    420

cacacccact cagctccgtg aacttgtgag aacacagccg attcacctga gcaggacctc    480

tgaaaccctg gaccagtggt ctcacatggt gctacgcctg catgtaaaca cgcctgcaaa    540

cgctgcctgc cggtaaacac gcctgcaaac gctgcctgcc cgtaaacacg cctgcaaacg    600

ctgcctgccc acacaggttc acgtgcagct caaggaaagg cctgaaagga gcccttatct    660

gtgctcagga ctcagaagcc tctgggtcag tggtccacat cccgggacgc agcaggaggc    720

caggccggcg agccctgtgg atgagccctc agaacccttg gcttgcccac gtggaaaagg    780

gatagaggtt gggtttcccc ccttttatag atggtcacgc acctgggtgt tacaaagttg    840

tatgtggcat gaatactttt tgtaatgatt gattaaatgc aagatagttt atctaa        896


<210>  8627
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  8627

Met Ala Glu Cys Pro Thr Leu Gly Glu Ala Val Thr Asp His Pro Asp 
1               5                   10                  15


Arg Leu Trp Ala Trp Glu Lys Phe Val Tyr Leu Asp Glu Lys Gln His 
            20                  25                  30


Ala Trp Leu Pro Leu Thr Ile Glu Ile Lys Asp Arg Leu Gln Leu Arg 
        35                  40                  45


Val Leu Leu Arg Arg Glu Asp Val Val Leu Gly Arg Pro Met Thr Pro 
    50                  55                  60


Thr Gln Ile Gly Pro Ser Leu Leu Pro Ile Met Trp Gln Leu Tyr Pro 
65                  70                  75                  80


Asp Gly Arg Tyr Arg Ser Ser Asp Ser Ser Phe Trp Arg Leu Val Tyr 
                85                  90                  95


His Ile Lys Ile Asp Gly Val Glu Asp Met Leu Leu Glu Leu Leu Pro 
            100                 105                 110


Asp Asp 



<210>  8628
<211>  1240
<212>  DNA
<213>  Homo sapiens

<400>  8628
gccgtcctcc cgccccgccg cttggtggcg gccgcatgct gcccggatat aaagggtcgg     60

ccccacatcc cagggaccag cgagcggcct tgagaggctc tggctcttgc ttcttaggcg    120

gcccgaggac gccatggccg agtgcccgac actcggggag gcagtcaccg accacccgga    180

ccgcctgtgg gcctgggaga agttcgtgta tttggacgag aagcagcacg cctggctgcc    240

cttaaccatc gagataaagg ataggttaca gttacgggtg ctcttgcgtc gggaagacgt    300

cgtcctgggg aggcctatga cccccaccca gataggccca agcctgctgc ctatcatgtg    360

gcagctctac cctgatggac gataccgatc ctcagactcc agtttctggc gcttagtgta    420

ccacatcaag attgacggcg tggaggacat gcttctcgag ctgctgccag atgactgatg    480

tatggtcttg gcagcacctg tctcctttca ccccagggcc tgagcctggc cagcctacaa    540

tggggatgtt gtgtttctgt tcaccttcgt ttactatgcc tgtgtcttct ccaccacgct    600

ggggtctggg aggaatggac agacagagga tgagctctac ccagggcctg caggacctgc    660

ctgtagccca ctctatacct gtgcctcggc ttttctcagc tggatgatgg tcttcagcct    720

ctttctgtcc cttctgtccc tcacagcact agtatttcat gttgcacacc cactcagctc    780

cgtgaacttg tgagaacaca gccgattcac ctgagcagga cctctgaaac cctggaccag    840

tggtctcaca tggtgctacg cctgcatgta aacacgcctg caaacgctgc ctgccggtaa    900

acacgcctgc aaacgctgcc tgcccgtaaa cacgcctgca aacgctgcct gcccacacag    960

gttcacgtgc agctcaagga aaggcctgaa aggagccctt atctgtgctc aggactcaga   1020

agcctctggg tcagtggtcc acatcccggg acgcagcagg aggccaggcc ggcgagccct   1080

gtggatgagc cctcagaacc cttggcttgc ccacgtggaa aagggataga ggttgggttt   1140

cccccctttt atagatggtc acgcacctgg gtgttacaaa gttgtatgtg gcatgaatac   1200

tttttgtaat gattgattaa atgcaagata gtttatctaa                         1240


<210>  8629
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  8629

Met Ala Glu Cys Pro Thr Leu Gly Glu Ala Val Thr Asp His Pro Asp 
1               5                   10                  15


Arg Leu Trp Ala Trp Glu Lys Phe Val Tyr Leu Asp Glu Lys Gln His 
            20                  25                  30


Ala Trp Leu Pro Leu Thr Ile Glu Ile Lys Asp Arg Leu Gln Leu Arg 
        35                  40                  45


Val Leu Leu Arg Arg Glu Asp Val Val Leu Gly Arg Pro Met Thr Pro 
    50                  55                  60


Thr Gln Ile Gly Pro Ser Leu Leu Pro Ile Met Trp Gln Leu Tyr Pro 
65                  70                  75                  80


Asp Gly Arg Tyr Arg Ser Ser Asp Ser Ser Phe Trp Arg Leu Val Tyr 
                85                  90                  95


His Ile Lys Ile Asp Gly Val Glu Asp Met Leu Leu Glu Leu Leu Pro 
            100                 105                 110


Asp Asp 



<210>  8630
<211>  1038
<212>  DNA
<213>  Homo sapiens

<400>  8630
gaaggctggt gggaggaggg gcagtctcca agagcccctg aaatcctcac acctgggttc     60

ctacctgctg tttccagcta ggggaaggcg caggagtgag gaatggaggg agtggagggc    120

tctggccgat caatgccttc tctctctctc tgcctctcag attgacggcg tggaggacat    180

gcttctcgag ctgctgccag atgactgatg tatggtcttg gcagcacctg tctcctttca    240

ccccagggcc tgagcctggc cagcctacaa tggggatgtt gtgtttctgt tcaccttcgt    300

ttactatgcc tgtgtcttct ccaccacgct ggggtctggg aggaatggac agacagagga    360

tgagctctac ccagggcctg caggacctgc ctgtagccca ctctgctcgc cttagcacta    420

ccactcctgc caaggaggat tccatttggc agagcttctt ccaggtgccc agctatacct    480

gtgcctcggc ttttctcagc tggatgatgg tcttcagcct ctttctgtcc cttctgtccc    540

tcacagcact agtatttcat gttgcacacc cactcagctc cgtgaacttg tgagaacaca    600

gccgattcac ctgagcagga cctctgaaac cctggaccag tggtctcaca tggtgctacg    660

cctgcatgta aacacgcctg caaacgctgc ctgccggtaa acacgcctgc aaacgctgcc    720

tgcccgtaaa cacgcctgca aacgctgcct gcccacacag gttcacgtgc agctcaagga    780

aaggcctgaa aggagccctt atctgtgctc aggactcaga agcctctggg tcagtggtcc    840

acatcccggg acgcagcagg aggccaggcc ggcgagccct gtggatgagc cctcagaacc    900

cttggcttgc ccacgtggaa aagggataga ggttgggttt cccccctttt atagatggtc    960

acgcacctgg gtgttacaaa gttgtatgtg gcatgaatac tttttgtaat gattgattaa   1020

atgcaagata gtttatct                                                 1038


<210>  8631
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8631

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8632
<211>  1098
<212>  DNA
<213>  Homo sapiens

<400>  8632
cgatcctcct gcctctgcct tccaaagcac tggaattaca agtataaagg ataggttaca     60

gttacgggtg ctcttgcgtc gggaagacgt cgtcctgggg aggcctatga cccccaccca    120

gataggccca agcctgctgc ctatcatgtg gcagctctac cctgatggac gataccgatc    180

ctcagactcc agtttctggc gcttagtgta ccacatcaag attgacggcg tggaggacat    240

gcttctcgag ctgctgccag atgactgatg tatggtcttg gcagcacctg tctcctttca    300

ccccagggcc tgagcctggc cagcctacaa tggggatgtt gtgtttctgt tcaccttcgt    360

ttactatgcc tgtgtcttct ccaccacgct ggggtctggg aggaatggac agacagagga    420

tgagctctac ccagggcctg caggacctgc ctgtagccca ctctgctcgc cttagcacta    480

ccactcctgc caaggaggat tccatttggc agagcttctt ccaggtgccc agctatacct    540

gtgcctcggc ttttctcagc tggatgatgg tcttcagcct ctttctgtcc cttctgtccc    600

tcacagcact agtatttcat gttgcacacc cactcagctc cgtgaacttg tgagaacaca    660

gccgattcac ctgagcagga cctctgaaac cctggaccag tggtctcaca tggtgctacg    720

cctgcatgta aacacgcctg caaacgctgc ctgccggtaa acacgcctgc aaacgctgcc    780

tgcccgtaaa cacgcctgca aacgctgcct gcccacacag gttcacgtgc agctcaagga    840

aaggcctgaa aggagccctt atctgtgctc aggactcaga agcctctggg tcagtggtcc    900

acatcccggg acgcagcagg aggccaggcc ggcgagccct gtggatgagc cctcagaacc    960

cttggcttgc ccacgtggaa aagggataga ggttgggttt cccccctttt atagatggtc   1020

acgcacctgg gtgttacaaa gttgtatgtg gcatgaatac tttttgtaat gattgattaa   1080

atgcaagata gtttatct                                                 1098


<210>  8633
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8633

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8634
<211>  1460
<212>  DNA
<213>  Homo sapiens

<400>  8634
gggaccagcg agcggccttg agaggctctg gctcttgctt cttaggcggc ccgaggacgc     60

catggccgag tgcccgacac tcggggaggc agtcaccgac cacccggacc gcctgtgggc    120

ctgggagaag ttcgtgtatt tggacgagaa gcagcacgcc tggctgccct taaccatcga    180

gatacagggt ctcgctctgt gacccaggct ggtcttaaac tcctggcctc aagcgatcct    240

cctgcctctg ccttccaaag cactggaatt acaagtgtga gccgctgcaa cccgccagaa    300

aaaagtgtgc ctttcatggc cctgtctggg tggctagaca cgtgtgtgtg ctggtggtcc    360

tggcccagcc agagtccctg agaggagcat gcatggccta aggaaataaa ggataggtta    420

cagttacggg tgctcttgcg tcgggaagac gtcgtcctgg ggaggcctat gacccccacc    480

cagataggcc caagcctgct gcctatcatg tggcagctct accctgatgg acgataccga    540

tcctcagact ccagtttctg gcgcttagtg taccacatca agattgacgg cgtggaggac    600

atgcttctcg agctgctgcc agatgactga tgtatggtct tggcagcacc tgtctccttt    660

caccccaggg cctgagcctg gccagcctac aatggggatg ttgtgtttct gttcaccttc    720

gtttactatg cctgtgtctt ctccaccacg ctggggtctg ggaggaatgg acagacagag    780

gatgagctct acccagggcc tgcaggacct gcctgtagcc cactctgctc gccttagcac    840

taccactcct gccaaggagg attccatttg gcagagcttc ttccaggtgc ccagctatac    900

ctgtgcctcg gcttttctca gctggatgat ggtcttcagc ctctttctgt cccttctgtc    960

cctcacagca ctagtatttc atgttgcaca cccactcagc tccgtgaact tgtgagaaca   1020

cagccgattc acctgagcag gacctctgaa accctggacc agtggtctca catggtgcta   1080

cgcctgcatg taaacacgcc tgcaaacgct gcctgccggt aaacacgcct gcaaacgctg   1140

cctgcccgta aacacgcctg caaacgctgc ctgcccacac aggttcacgt gcagctcaag   1200

gaaaggcctg aaaggagccc ttatctgtgc tcaggactca gaagcctctg ggtcagtggt   1260

ccacatcccg ggacgcagca ggaggccagg ccggcgagcc ctgtggatga gccctcagaa   1320

cccttggctt gcccacgtgg aaaagggata gaggttgggt ttcccccctt ttatagatgg   1380

tcacgcacct gggtgttaca aagttgtatg tggcatgaat actttttgta atgattgatt   1440

aaatgcaaga tagtttatct                                               1460


<210>  8635
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8635

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8636
<211>  1308
<212>  DNA
<213>  Homo sapiens

<400>  8636
gccgtcctcc cgccccgccg cttggtggcg gccgcatgct gcccggatat aaagggtcgg     60

ccccacatcc cagggaccag cgagcggcct tgagaggctc tggctcttgc ttcttaggcg    120

gcccgaggac gccatggccg agtgcccgac actcggggag gcagtcaccg accacccgga    180

ccgcctgtgg gcctgggaga agttcgtgta tttggacgag aagcagcacg cctggctgcc    240

cttaaccatc gagataaagg ataggttaca gttacgggtg ctcttgcgtc gggaagacgt    300

cgtcctgggg aggcctatga cccccaccca gataggccca agcctgctgc ctatcatgtg    360

gcagctctac cctgatggac gataccgatc ctcagactcc agtttctggc gcttagtgta    420

ccacatcaag attgacggcg tggaggacat gcttctcgag ctgctgccag atgactgatg    480

tatggtcttg gcagcacctg tctcctttca ccccagggcc tgagcctggc cagcctacaa    540

tggggatgtt gtgtttctgt tcaccttcgt ttactatgcc tgtgtcttct ccaccacgct    600

ggggtctggg aggaatggac agacagagga tgagctctac ccagggcctg caggacctgc    660

ctgtagccca ctctgctcgc cttagcacta ccactcctgc caaggaggat tccatttggc    720

agagcttctt ccaggtgccc agctatacct gtgcctcggc ttttctcagc tggatgatgg    780

tcttcagcct ctttctgtcc cttctgtccc tcacagcact agtatttcat gttgcacacc    840

cactcagctc cgtgaacttg tgagaacaca gccgattcac ctgagcagga cctctgaaac    900

cctggaccag tggtctcaca tggtgctacg cctgcatgta aacacgcctg caaacgctgc    960

ctgccggtaa acacgcctgc aaacgctgcc tgcccgtaaa cacgcctgca aacgctgcct   1020

gcccacacag gttcacgtgc agctcaagga aaggcctgaa aggagccctt atctgtgctc   1080

aggactcaga agcctctggg tcagtggtcc acatcccggg acgcagcagg aggccaggcc   1140

ggcgagccct gtggatgagc cctcagaacc cttggcttgc ccacgtggaa aagggataga   1200

ggttgggttt cccccctttt atagatggtc acgcacctgg gtgttacaaa gttgtatgtg   1260

gcatgaatac tttttgtaat gattgattaa atgcaagata gtttatct                1308


<210>  8637
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  8637

Met Thr Asp Val Trp Ser Trp Gln His Leu Ser Pro Phe Thr Pro Gly 
1               5                   10                  15


Pro Glu Pro Gly Gln Pro Thr Met Gly Met Leu Cys Phe Cys Ser Pro 
            20                  25                  30


Ser Phe Thr Met Pro Val Ser Ser Pro Pro Arg Trp Gly Leu Gly Gly 
        35                  40                  45


Met Asp Arg Gln Arg Met Ser Ser Thr Gln Gly Leu Gln Asp Leu Pro 
    50                  55                  60


Val Ala His Ser Ala Arg Leu Ser Thr Thr Thr Pro Ala Lys Glu Asp 
65                  70                  75                  80


Ser Ile Trp Gln Ser Phe Phe Gln Val Pro Ser Tyr Thr Cys Ala Ser 
                85                  90                  95


Ala Phe Leu Ser Trp Met Met Val Phe Ser Leu Phe Leu Ser Leu Leu 
            100                 105                 110


Ser Leu Thr Ala Leu Val Phe His Val Ala His Pro Leu Ser Ser Val 
        115                 120                 125


Asn Leu 
    130


<210>  8638
<211>  714
<212>  DNA
<213>  Homo sapiens

<400>  8638
gggaccagcg agcggccttg agaggctctg gctcttgctt cttaggcggc ccgaggacgc     60

catggccgag tgcccgacac tcggggaggc agtcaccgac cacccggacc gcctgtgggc    120

ctgggagaag ttcgtgtatt tggacgagaa gcagcacgcc tggctgccct taaccatcga    180

gataaaggat aggttacagt tacgggtgct cttgcgtcgg gaagacgtcg tcctggggag    240

gcctatgacc cccacccaga taggcccaag cctgctgcct atcatgtggc agctctaccc    300

tgatggacga taccgatcct cagactccag tttctggcgc ttagtgtacc acatcaagat    360

tgacggcgtg gaggacatgc ttctcgagct gctgccagat gactgatgta tggtgagctc    420

cactggagcc tgacccctct tagtccacag tggctgtatc agaaagaaag accacccctt    480

ctccatgaag gcagtgctaa cccctccccg actgctgcca tctgagggtc cctagggatg    540

ggagaggctt cctggaggca ctcatgtctc ccttaccact tcgggagcca agggctttgt    600

aggcagcccc ctttatcgca gctgctcata tctataaagt acttcacaag tttcagctgg    660

cactttcatt taccattgct tttttttttt tttgagatga gtctggctct gtgg          714


<210>  8639
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  8639

Met Ala Glu Cys Pro Thr Leu Gly Glu Ala Val Thr Asp His Pro Asp 
1               5                   10                  15


Arg Leu Trp Ala Trp Glu Lys Phe Val Tyr Leu Asp Glu Lys Gln His 
            20                  25                  30


Ala Trp Leu Pro Leu Thr Ile Glu Ile Lys Asp Arg Leu Gln Leu Arg 
        35                  40                  45


Val Leu Leu Arg Arg Glu Asp Val Val Leu Gly Arg Pro Met Thr Pro 
    50                  55                  60


Thr Gln Ile Gly Pro Ser Leu Leu Pro Ile Met Trp Gln Leu Tyr Pro 
65                  70                  75                  80


Asp Gly Arg Tyr Arg Ser Ser Asp Ser Ser Phe Trp Arg Leu Val Tyr 
                85                  90                  95


His Ile Lys Ile Asp Gly Val Glu Asp Met Leu Leu Glu Leu Leu Pro 
            100                 105                 110


Asp Asp 



<210>  8640
<211>  2779
<212>  DNA
<213>  Homo sapiens

<400>  8640
agtcatctgg cagcagctcg agaagcatgt cctccacgcc gtcaatctga gaggcagaga     60

gagagagaag gcattgatcg gccagagccc tccactccct ccattcctca ctcctgcgcc    120

ttcccctagc tggaaacagc aggtaggaac ccaggtgtga ggatttcagg ggctcttgga    180

gactgcccct cctcccacca gccttcagcc tgtgactgcc caccagagat gtcttcctgc    240

ggctagctgg tggctgggag gaagtggagg ctggaatgca atggtgtgat cttggctcac    300

tgcgacctcc acctcctggg ttcaagcgat tctcctgctt ctgcctcccg agtagctggg    360

attacagaca aagaattcaa gactaaactg ggcatggtga cacgcacctg tagtctcagc    420

tacttgggag gctgaggcag gagaatcaca tgaacctggc aggcggaggt tgcagtgagc    480

cgagattgtg ccactgcact ccagcctggc cacagagcga gactccgtct caaaaaaaaa    540

aaaaaaagaa aaaaagaaaa aagaagaagt caagactaag aagagtgaag tatgaagtaa    600

ttcacccaca gacacccagc tagtgagtgg cagacctgga agacaaacta gttctgtttg    660

gcatcagaat ctatgctgtc agccacctca ccacattcat gtgacatcca acaaagtggt    720

gccttcacct gctactaagt cttgctaggg ctagttccag agccaagact atgaagtgga    780

caatgatcta tgaagcgcta agtgaacaga tgtcatgtaa atagcttgga tctctacgtg    840

catgtgtgca ttgtatatgt ttaccaaaga ccttgttaca gtgtttttag gcatggctca    900

ctttataaag gtcatcacag ttggccaagc tatctggtat ttattactca tttgatactc    960

acacctgctc aatgatgctg gtatcattac tctccataat gattttccta tcattttaca   1020

gatggggttc agaaagatca ggtggtagat ccatagtcac actctagtta attgatagga   1080

ctgagaattc aatgcatgcc cactgccttc tcttacaagt cttggggtat ttgagtgtaa   1140

ttcaataatg acaacccctt cactgtccaa aaggggtgaa tgaaacatca agctgtcaca   1200

aaggctaggt tggagggcat ggcttatatc cttgggtaag taggcttact aaacttaaac   1260

cctaaagttg aactgactta actaccccgt cccagcagct ggagtgggac aggacactgg   1320

gtctatatgg agaggggtct gcccagatta gctttaggac gtggagaagc agagaactca   1380

tgttcctaca aacaggttca ctctcaagat aaagacaagg aaccaaactc agcctgcctg   1440

cttcattttt tcatatttgc caatcagata agtcacttcc gcccccagag agatttaata   1500

aaggagcaga gaaagacttc taataaaatt ccctccatat ggaaggaaaa ggagacatcg   1560

ggagttacgt taatcatgct catttcttaa cagtgcaaat atcaagagtt agaaattaga   1620

gttcctggct gggtgcggtg cctcactcct gtaatcctag cactttggaa ggccaaggca   1680

ggtggattgc cggagctcag gagttcgaga ccagcctggg caacacggtg aaaccttgtc   1740

tctactaaaa tacaaaaaaa tagccaggcg tggcagcgtg cacctgtaat cccagctact   1800

caggaggcta aggcaggaga attgcttgaa caagggagcc agaggttgca gtgagctgag   1860

attgcaccac tgcactccag cctgggtgac agagcgagac tctgtctcca aaaaaaaaaa   1920

acaaaacaga aataagagtt cccacatgac agcaagaatc actgaaaatg ctggacccac   1980

tgtcaatgct gtattgttgc aaagaaaatg tttatcttgc ctaactttaa agtcacacat   2040

gcctgggaac ttccaactag aacacagctg gcaaagcaga caccctctcc ctgcagcctc   2100

gttgaaaatg acctccttta catttcctca ttgagaatct gcccagtgag gactgtggca   2160

gaagagagtc agggagaatt ttctagctga ttagggttag aaaatgaaga cgagggctct   2220

cttgtaatca gcaggaagct atgatagaaa agaatgcctt ttaaatttga agtgcaaaac   2280

tagaaaatag aaaattatta ggggggtttg atatgaagtt tcggaattct tttcaagact   2340

gtgtgttttg aagttaagat tttaaataat gtaggaaggt acagtctata ctgatgggtt   2400

caggatatgc taacccaaaa tatggcacct tggtgtttga gaaaatggcg gaagcaggaa   2460

ggtcattctc accatccacc tccctttccc cctcctgaag caggtcttct ttgaaaggcc   2520

cctccctgta accagaagaa aggaacattc ttacctttga agtcacaggg tcacagagaa   2580

gaatctgaac aggacttact aaattcttcc agtttgtcac catttgctca taccatcttt   2640

gtccagttat atttctccaa agctatccac tcttcatcaa acttagcata aaaattgtaa   2700

aaccttacac atttcttcag gtcttccttt tccttaggaa gcctcccatg tcacatgaaa   2760

cttaaataaa ataaatctg                                                2779


<210>  8641
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  8641

Met Gln Trp Cys Asp Leu Gly Ser Leu Arg Pro Pro Pro Pro Gly Phe 
1               5                   10                  15


Lys Arg Phe Ser Cys Phe Cys Leu Pro Ser Ser Trp Asp Tyr Arg Gln 
            20                  25                  30


Arg Ile Gln Asp 
        35


<210>  8642
<211>  2652
<212>  DNA
<213>  Homo sapiens

<400>  8642
agtcatctgg cagcagctcg agaagcatgt cctccacgcc gtcaatctga gaggcagaga     60

gagagagaag gcattgatcg gccagagccc tccactccct ccattcctca ctcctgcgcc    120

ttcccctagc tggaaacagc aggctggaat gcaatggtgt gatcttggct cactgcgacc    180

tccacctcct gggttcaagc gattctcctg cttctgcctc ccgagtagct gggattacag    240

acaaagaatt caagactaaa ctgggcatgg tgacacgcac ctgtagtctc agctacttgg    300

gaggctgagg caggagaatc acatgaacct ggcaggcgga ggttgcagtg agccgagatt    360

gtgccactgc actccagcct ggccacagag cgagactccg tctcaaaaaa aaaaaaaaaa    420

gaaaaaaaga aaaaagaaga agtcaagact aagaagagtg aagtatgaag taattcaccc    480

acagacaccc agctagtgag tggcagacct ggaagacaaa ctagttctgt ttggcatcag    540

aatctatgct gtcagccacc tcaccacatt catgtgacat ccaacaaagt ggtgccttca    600

cctgctacta agtcttgcta gggctagttc cagagccaag actatgaagt ggacaatgat    660

ctatgaagcg ctaagtgaac agatgtcatg taaatagctt ggatctctac gtgcatgtgt    720

gcattgtata tgtttaccaa agaccttgtt acagtgtttt taggcatggc tcactttata    780

aaggtcatca cagttggcca agctatctgg tatttattac tcatttgata ctcacacctg    840

ctcaatgatg ctggtatcat tactctccat aatgattttc ctatcatttt acagatgggg    900

ttcagaaaga tcaggtggta gatccatagt cacactctag ttaattgata ggactgagaa    960

ttcaatgcat gcccactgcc ttctcttaca agtcttgggg tatttgagtg taattcaata   1020

atgacaaccc cttcactgtc caaaaggggt gaatgaaaca tcaagctgtc acaaaggcta   1080

ggttggaggg catggcttat atccttgggt aagtaggctt actaaactta aaccctaaag   1140

ttgaactgac ttaactaccc cgtcccagca gctggagtgg gacaggacac tgggtctata   1200

tggagagggg tctgcccaga ttagctttag gacgtggaga agcagagaac tcatgttcct   1260

acaaacaggt tcactctcaa gataaagaca aggaaccaaa ctcagcctgc ctgcttcatt   1320

ttttcatatt tgccaatcag ataagtcact tccgccccca gagagattta ataaaggagc   1380

agagaaagac ttctaataaa attccctcca tatggaagga aaaggagaca tcgggagtta   1440

cgttaatcat gctcatttct taacagtgca aatatcaaga gttagaaatt agagttcctg   1500

gctgggtgcg gtgcctcact cctgtaatcc tagcactttg gaaggccaag gcaggtggat   1560

tgccggagct caggagttcg agaccagcct gggcaacacg gtgaaacctt gtctctacta   1620

aaatacaaaa aaatagccag gcgtggcagc gtgcacctgt aatcccagct actcaggagg   1680

ctaaggcagg agaattgctt gaacaaggga gccagaggtt gcagtgagct gagattgcac   1740

cactgcactc cagcctgggt gacagagcga gactctgtct ccaaaaaaaa aaaacaaaac   1800

agaaataaga gttcccacat gacagcaaga atcactgaaa atgctggacc cactgtcaat   1860

gctgtattgt tgcaaagaaa atgtttatct tgcctaactt taaagtcaca catgcctggg   1920

aacttccaac tagaacacag ctggcaaagc agacaccctc tccctgcagc ctcgttgaaa   1980

atgacctcct ttacatttcc tcattgagaa tctgcccagt gaggactgtg gcagaagaga   2040

gtcagggaga attttctagc tgattagggt tagaaaatga agacgagggc tctcttgtaa   2100

tcagcaggaa gctatgatag aaaagaatgc cttttaaatt tgaagtgcaa aactagaaaa   2160

tagaaaatta ttaggggggt ttgatatgaa gtttcggaat tcttttcaag actgtgtgtt   2220

ttgaagttaa gattttaaat aatgtaggaa ggtacagtct atactgatgg gttcaggata   2280

tgctaaccca aaatatggca ccttggtgtt tgagaaaatg gcggaagcag gaaggtcatt   2340

ctcaccatcc acctcccttt ccccctcctg aagcaggtct tctttgaaag gcccctccct   2400

gtaaccagaa gaaaggaaca ttcttacctt tgaagtcaca gggtcacaga gaagaatctg   2460

aacaggactt actaaattct tccagtttgt caccatttgc tcataccatc tttgtccagt   2520

tatatttctc caaagctatc cactcttcat caaacttagc ataaaaattg taaaacctta   2580

cacatttctt caggtcttcc ttttccttag gaagcctccc atgtcacatg aaacttaaat   2640

aaaataaatc tg                                                       2652


<210>  8643
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  8643

Met Gln Trp Cys Asp Leu Gly Ser Leu Arg Pro Pro Pro Pro Gly Phe 
1               5                   10                  15


Lys Arg Phe Ser Cys Phe Cys Leu Pro Ser Ser Trp Asp Tyr Arg Gln 
            20                  25                  30


Arg Ile Gln Asp 
        35


<210>  8644
<211>  614
<212>  DNA
<213>  Homo sapiens

<400>  8644
gccttgagag gctctggctc ttgcttctta ggcggcccga ggacgccatg gccgagtgcc     60

cgacactcgg ggaggcagtc accgaccacc cggaccgcct gtgggcctgg gagaagttcg    120

tgtatttgga cgagaagcag cacgcctggc tgcccttaac catcgagata cagggtctcg    180

ctctgtgacc caggctggtc ttaaactcct ggcctcaagc gatcctcctg cctctgcctt    240

ccaaagcact ggaattacaa gtgtgagccg ctgcaacccg ccagaaaaaa gtgtgccttt    300

catggccctg tctgggtggc tagacacgtg tgtgtgctgg tggtcctggc ccagccagag    360

tccctgagag gagcatgcat ggcctaagga agtgagcttc agggaacagt gatgaccatc    420

atttcacact cggacccctg cccagatggg tggatggctg gcaggaggga ttccggtttt    480

ctgcgcctgg agaagccctg gcaagcggaa cctgaaagta tgccctgtcc ttttcttctc    540

ctcagataaa ggataggtta cagttacggg tgctcttgcg tcgggaagac gtcgtcctgg    600

ggaggcctat gacc                                                      614


<210>  8645
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  8645

Met Ala Glu Cys Pro Thr Leu Gly Glu Ala Val Thr Asp His Pro Asp 
1               5                   10                  15


Arg Leu Trp Ala Trp Glu Lys Phe Val Tyr Leu Asp Glu Lys Gln His 
            20                  25                  30


Ala Trp Leu Pro Leu Thr Ile Glu Ile Gln Gly Leu Ala Leu 
        35                  40                  45


<210>  8646
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  8646
ggactgcccg ggaggagtct ccacgccatg tgagtcaatc agggaaccct gggcaattgc     60

aaactgatcg tagaaggcgg agttgtccac gcccagctcc aagtcgatgt cctggagctc    120

ttcacagctg tggggtacgg tgcccttctc ggtgatggtg tcgcaccaca tggtgaagcc    180

cacgctcacg atggtgctgg caatgaagac caggaagacc acgaaggcgc tgaccaggag    240

gttcaggaag gcggagaaga aggagccctc gtgtcccttg cagaggaaga agagcgtgcg    300

ccaggcgtgc gcggcggcca gcagcagaga caggaggctg gcgagcaggc tgaagcggca    360

ggcggccggc gggccccact cctgcaccgt gaagcgctcg cgctcctgca ccgtgaggtt    420

ggcgctcagc cacatgccct cggtgaagag caggcagcgg ccgcggaagt cgtggccgtt    480

ctcggacagc gggaccacca ccacgaagct gaacaggaag gccaagaagt agcaggcgca    540

ctgagcgaaa aggaaattgt tgagcgccat ggccggcccg ggcgagagc                589


<210>  8647
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8647

Met Ser Trp Ser Ser Ser Gln Leu Trp Gly Thr Val Pro Phe Ser Val 
1               5                   10                  15


Met Val Ser His His Met Val Lys Pro Thr Leu Thr Met Val Leu Ala 
            20                  25                  30


Met Lys Thr Arg Lys Thr Thr Lys Ala Leu Thr Arg Arg Phe Arg Lys 
        35                  40                  45


Ala Glu Lys Lys Glu Pro Ser Cys Pro Leu Gln Arg Lys Lys Ser Val 
    50                  55                  60


Arg Gln Ala Cys Ala Ala Ala Ser Ser Arg Asp Arg Arg Leu Ala Ser 
65                  70                  75                  80


Arg Leu Lys Arg Gln Ala Ala Gly Gly Pro His Ser Cys Thr Val Lys 
                85                  90                  95


Arg Ser Arg Ser Cys Thr Val Arg Leu Ala Leu Ser His Met Pro Ser 
            100                 105                 110


Val Lys Ser Arg Gln Arg Pro Arg Lys Ser Trp Pro Phe Ser Asp Ser 
        115                 120                 125


Gly Thr Thr Thr Thr Lys Leu Asn Arg Lys Ala Lys Lys 
    130                 135                 140


<210>  8648
<211>  597
<212>  DNA
<213>  Homo sapiens

<400>  8648
cagctttgcg atccagcaga gagggctgga gacgggacga aggccacaac agacccggcc     60

ctgccagcgg gcggtggcgc ctccagatca gagccctcgg gaaggaggcc tgggcgggcc    120

tggcccgttc acctgtgtgc cctgcagttc tgcccgaggc tcaactctca agggcctggg    180

aggggtgctg ccggccaaga gggtccagga cctcactgga ctgtgcccca cagggagatc    240

ccgaagagcc tgtttctgtc cctcggggag ccaggaggga accaggacca tgttccagta    300

aatgaggact gcagcaggag ccgtgagccc tgactcccgg ccagagacac gacgtcagac    360

cagaaagaat gaggaggccg cgtggggccc gcgggtgtgc agggcagaga gggaggacaa    420

caggaagtgc cccccctcca tcctgaaacg gagccggccg gagcaccacc gcccagaggc    480

caagccccag aggacctcga ggcgcgtgtg gttccgagaa cccccagcgg tgaccgtcca    540

ctacattgct gacaagaacg ccacagccac tgtcagggct gtgtgtgtgc gtcctgc       597


<210>  8649
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  8649

Met Arg Thr Ala Ala Gly Ala Val Ser Pro Asp Ser Arg Pro Glu Thr 
1               5                   10                  15


Arg Arg Gln Thr Arg Lys Asn Glu Glu Ala Ala Trp Gly Pro Arg Val 
            20                  25                  30


Cys Arg Ala Glu Arg Glu Asp Asn Arg Lys Cys Pro Pro Ser Ile Leu 
        35                  40                  45


Lys Arg Ser Arg Pro Glu His His Arg Pro Glu Ala Lys Pro Gln Arg 
    50                  55                  60


Thr Ser Arg Arg Val Trp Phe Arg Glu Pro Pro Ala Val Thr Val His 
65                  70                  75                  80


Tyr Ile Ala Asp Lys Asn Ala Thr Ala Thr Val Arg Ala Val Cys Val 
                85                  90                  95


Arg 



<210>  8650
<211>  1848
<212>  DNA
<213>  Homo sapiens

<400>  8650
cagctttgcg atccagcaga gagggctgga gacgggacga aggccacaac agacccggcc     60

ctgccagcgg gcggtggcgc ctccagatca gagccctcgg gaaggaggcc tgggcgggcc    120

tggcccgttc acctgtgtgc cctgcagttc tgcccgaggc tcaactctca agggcctggg    180

aggggtgctg ccggccaaga gggtccagga cctcactgga ctgtgcccca cagggagatc    240

ccgaagagcc tgtttctgtc cctcggggag ccaggaggga accaggacca tgttccagta    300

aatgaggact gcagcaggag ccgtgagccc tgactcccgg ccagagacac gacgtcagac    360

cagaaagaat gaggaggccg cgtggggccc gcgggtgtgc agggcagaga gggaggacaa    420

caggaagtgc cccccctcca tcctgaaacg gagccggccg gagcaccacc gcccagaggc    480

caagccccag aggacctcga ggcgcgtgtg gttccgagaa cccccagcgg tgaccgtcca    540

ctacattgct gacaagaacg ccacagccac tgtcagggtg cccggccggc ccaggccaca    600

cggcggctcc ctgctcctgc agctgtgtgt gtgcgtcctg ctcgtgctgg ccctgggcct    660

atactgcggc cgggccaagc ccgtggcaac ggcactggag gacctgcggg cccggctcct    720

cggccttgtc ctgcacctgc ggcacgtggc cctcacctgc tggcgcggcc tcctgcggct    780

ctgacgggca ggacgggcag gacgggcagg gcttccagga gagctcaagc actccggggg    840

ctccgagaca gcctgagccc tggccctgct gcttggtgaa tcatgggggc caaaaggggc    900

tgctgcctga gggctaacta ggaaaagggg gaccccgtgg cgtgagatcg gacatggggg    960

gcacagcagg cggccccgcc acactagtca gcacagccct cctgtctcct gtgttgggtc   1020

catgtgagat tttattagaa agaggattcg actgctaaca gttgaggctc cccaggctca   1080

cccaaagacc cctccctcgt cccagcagga actcctgctg ctgctagggc ctggcccggc   1140

catcaccgtg tgcaccctct tgaggagggg gacacactgc ccgtgttcaa ggggctgctc   1200

ggaggaggca aacccagcct tttgcgatta tggcttgtgg ggaatccaga cctcgaaacc   1260

ccacggggag ggaagggtct ggttgtcaag gtgggtccct ttgatgtgag gtgccatcct   1320

ctgagcccag gtctgacccc cctacccagc cccgtgagtc tggagaggcc ccagggaagg   1380

acccctcatc aggggcggct tcaggtgtag aagccgaggg gacagcaagg ggcccagaca   1440

cccccgacct tcagaacagc catctgtgcc cagctctgca ggccaggcac acccagctga   1500

gcccggggcc agccagcacc acccaccagc tggggcctgt gggtcccgga gaccgtctgt   1560

ggttgtggct ttgtcgccgg attgcagagc tgaagggagc cctgtggatg acaaacacca   1620

ggggcctctc cagaccctac gtggggggag ggctgaacaa agcagggagg cccacggtta   1680

gacaccaggc agaactgccc aggagagaca cagggacaat cagaccagcg tcctcgaggt   1740

tagcctgagg cgggtgggca cggccgacca tccacccggt ggttcctgtt tgtcccacca   1800

cttaactggg agacactgtt ttattaaaac acaccgtggc ttccttca                1848


<210>  8651
<211>  160
<212>  PRT
<213>  Homo sapiens

<400>  8651

Met Arg Thr Ala Ala Gly Ala Val Ser Pro Asp Ser Arg Pro Glu Thr 
1               5                   10                  15


Arg Arg Gln Thr Arg Lys Asn Glu Glu Ala Ala Trp Gly Pro Arg Val 
            20                  25                  30


Cys Arg Ala Glu Arg Glu Asp Asn Arg Lys Cys Pro Pro Ser Ile Leu 
        35                  40                  45


Lys Arg Ser Arg Pro Glu His His Arg Pro Glu Ala Lys Pro Gln Arg 
    50                  55                  60


Thr Ser Arg Arg Val Trp Phe Arg Glu Pro Pro Ala Val Thr Val His 
65                  70                  75                  80


Tyr Ile Ala Asp Lys Asn Ala Thr Ala Thr Val Arg Val Pro Gly Arg 
                85                  90                  95


Pro Arg Pro His Gly Gly Ser Leu Leu Leu Gln Leu Cys Val Cys Val 
            100                 105                 110


Leu Leu Val Leu Ala Leu Gly Leu Tyr Cys Gly Arg Ala Lys Pro Val 
        115                 120                 125


Ala Thr Ala Leu Glu Asp Leu Arg Ala Arg Leu Leu Gly Leu Val Leu 
    130                 135                 140


His Leu Arg His Val Ala Leu Thr Cys Trp Arg Gly Leu Leu Arg Leu 
145                 150                 155                 160


<210>  8652
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  8652
acaacagacc cggccctgcc agcgggcggt ggcgcctcca gatcagagcc ctcgggaagg     60

aggcctgggc gggcctggcc cgttcacctg tgtgccctgc agttctgccc gaggctcaac    120

tctcaagggc ctgggagggg tgctgccggc caagagggtc caggacctca ctggactgtg    180

ccccacaggg agatcccgaa gagcctgttt ctgtccctcg gggagccagg agggaaccag    240

gaccatgttc cagtaaatga ggactgcagc aggagccgtg agccctgact cccggccaga    300

gacacgacgt cagaccagaa agaatgagga ggccgcgtgg ggcccgcggg tgtgcagggc    360

agagagggag gacaacagga agtgcccccc ctccatcctg aaacggagcc ggccggagca    420

ccaccgccca gaggccaagc cccagaggac ctcgaggcgc gtgtggttcc gagaaccccc    480

agcggtgacc gtccactaca ttgctgacaa gaacgccaca gccactgtca ggggtgagtt    540

ctgagcccac atccctgtgc cccactgccc cct                                 573


<210>  8653
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  8653

Met Arg Thr Ala Ala Gly Ala Val Ser Pro Asp Ser Arg Pro Glu Thr 
1               5                   10                  15


Arg Arg Gln Thr Arg Lys Asn Glu Glu Ala Ala Trp Gly Pro Arg Val 
            20                  25                  30


Cys Arg Ala Glu Arg Glu Asp Asn Arg Lys Cys Pro Pro Ser Ile Leu 
        35                  40                  45


Lys Arg Ser Arg Pro Glu His His Arg Pro Glu Ala Lys Pro Gln Arg 
    50                  55                  60


Thr Ser Arg Arg Val Trp Phe Arg Glu Pro Pro Ala Val Thr Val His 
65                  70                  75                  80


Tyr Ile Ala Asp Lys Asn Ala Thr Ala Thr Val Arg Gly Glu Phe 
                85                  90                  95


<210>  8654
<211>  561
<212>  DNA
<213>  Homo sapiens

<400>  8654
agacccggcc ctgccagcgg gcggtggcgc ctccagatca gagccctcgg gaaggaggcc     60

tgggcgggcc tggcccgttc acctgtgtgc cctgcagttc tgcccgaggc tcaactctca    120

agggcctggg aggggtgctg ccggccaaga gggtccagga ccatgttcca gtaaatgagg    180

actgcagcag gagccgtgag ccctgactcc cggccagaga cacgacgtca gaccagaaag    240

aatgaggagg ccgcgtgggg cccgcgggtg tgcagggcag agagggagga caacaggaag    300

tgccccccct ccatcctgaa acggagccgg ccggagcacc accgcccaga ggccaagccc    360

cagaggacct cgaggcgcgt gtggttccga gaacccccag cggtgaccgt ccactacatt    420

gctgacaaga acgccacagc cactgtcagg ggtgagttct gagcccacat ccctgtgccc    480

cactgccccc tccgtgggtg cacccaccct cactccctcc ccgagggagg tgtcacaggg    540

ccagggcctc taaggagtcc c                                              561


<210>  8655
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  8655

Met Arg Thr Ala Ala Gly Ala Val Ser Pro Asp Ser Arg Pro Glu Thr 
1               5                   10                  15


Arg Arg Gln Thr Arg Lys Asn Glu Glu Ala Ala Trp Gly Pro Arg Val 
            20                  25                  30


Cys Arg Ala Glu Arg Glu Asp Asn Arg Lys Cys Pro Pro Ser Ile Leu 
        35                  40                  45


Lys Arg Ser Arg Pro Glu His His Arg Pro Glu Ala Lys Pro Gln Arg 
    50                  55                  60


Thr Ser Arg Arg Val Trp Phe Arg Glu Pro Pro Ala Val Thr Val His 
65                  70                  75                  80


Tyr Ile Ala Asp Lys Asn Ala Thr Ala Thr Val Arg Gly Glu Phe 
                85                  90                  95


<210>  8656
<211>  2048
<212>  DNA
<213>  Homo sapiens

<400>  8656
gttccagtgg tgagcgttgg gctgggagcc aaggcttttc ccaggagccc agccaccccg     60

cctggctgtg ttctgcctcc gccctgcaga ggaaaggcca gcgaggcagt gtccatggtc    120

ccagtcttct tccaccggaa gaaggcacaa cctgcatctg cagccccagg gccattgggt    180

taggcctgtg gccaaactac taaggtgctg ggagactgag gaggcccagc tcctcctggg    240

gccaccaagc ccgtggttga cggcctcccc atggaccggg ctgtcccgag agcagcaagt    300

cagccggggc cctcagggcc gctgaggcca ctgctcagtg tcgccgtaat ggaaacttct    360

cagctggttg tgagccgcaa cagctctggt tcacaccctg cgacagcgag gctgtgaccg    420

ccagtggatc tcggggctga tcaggcctga gccaccccgg aggtacagca ccagcaggag    480

cccaggacca tgttccagta aatgaggact gcagcaggag ccgtgagccc tgactcccgg    540

ccagagacac gacgtcagac cagaaagaat gaggaggccg cgtggggccc gcgggtgtgc    600

agggcagaga gggaggacaa caggaagtgc cccccctcca tcctgaaacg gagccggccg    660

gagcaccacc gcccagaggc caagccccag aggacctcga ggcgcgtgtg gttccgagaa    720

cccccagcgg tgaccgtcca ctacattgct gacaagaacg ccacagccac tgtcagggtg    780

cccggccggc ccaggccaca cggcggctcc ctgctcctgc agctgtgtgt gtgcgtcctg    840

ctcgtgctgg ccctgggcct atactgcggc cgggccaagc ccgtggcaac ggcactggag    900

gacctgcggg cccggctcct cggccttgtc ctgcacctgc ggcacgtggc cctcacctgc    960

tggcgcggcc tcctgcggct ctgacgggca ggacgggcag gacgggcagg gcttccagga   1020

gagctcaagc actccggggg ctccgagaca gcctgagccc tggccctgct gcttggtgaa   1080

tcatgggggc caaaaggggc tgctgcctga gggctaacta ggaaaagggg gaccccgtgg   1140

cgtgagatcg gacatggggg gcacagcagg cggccccgcc acactagtca gcacagccct   1200

cctgtctcct gtgttgggtc catgtgagat tttattagaa agaggattcg actgctaaca   1260

gttgaggctc cccaggctca cccaaagacc cctccctcgt cccagcagga actcctgctg   1320

ctgctagggc ctggcccggc catcaccgtg tgcaccctct tgaggagggg gacacactgc   1380

ccgtgttcaa ggggctgctc ggaggaggca aacccagcct tttgcgatta tggcttgtgg   1440

ggaatccaga cctcgaaacc ccacggggag ggaagggtct ggttgtcaag gtgggtccct   1500

ttgatgtgag gtgccatcct ctgagcccag gtctgacccc cctacccagc cccgtgagtc   1560

tggagaggcc ccagggaagg acccctcatc aggggcggct tcaggtgtag aagccgaggg   1620

gacagcaagg ggcccagaca cccccgacct tcagaacagc catctgtgcc cagctctgca   1680

ggccaggcac acccagctga gcccggggcc agccagcacc acccaccagc tggggcctgt   1740

gggtcccgga gaccgtctgt ggttgtggct ttgtcgccgg attgcagagc tgaagggagc   1800

cctgtggatg acaaacacca ggggcctctc cagaccctac gtggggggag ggctgaacaa   1860

agcagggagg cccacggtta gacaccaggc agaactgccc aggagagaca cagggacaat   1920

cagaccagcg tcctcgaggt tagcctgagg cgggtgggca cggccgacca tccacccggt   1980

ggttcctgtt tgtcccacca cttaactggg agacactgtt ttattaaaac acaccgtggc   2040

ttccttca                                                            2048


<210>  8657
<211>  160
<212>  PRT
<213>  Homo sapiens

<400>  8657

Met Arg Thr Ala Ala Gly Ala Val Ser Pro Asp Ser Arg Pro Glu Thr 
1               5                   10                  15


Arg Arg Gln Thr Arg Lys Asn Glu Glu Ala Ala Trp Gly Pro Arg Val 
            20                  25                  30


Cys Arg Ala Glu Arg Glu Asp Asn Arg Lys Cys Pro Pro Ser Ile Leu 
        35                  40                  45


Lys Arg Ser Arg Pro Glu His His Arg Pro Glu Ala Lys Pro Gln Arg 
    50                  55                  60


Thr Ser Arg Arg Val Trp Phe Arg Glu Pro Pro Ala Val Thr Val His 
65                  70                  75                  80


Tyr Ile Ala Asp Lys Asn Ala Thr Ala Thr Val Arg Val Pro Gly Arg 
                85                  90                  95


Pro Arg Pro His Gly Gly Ser Leu Leu Leu Gln Leu Cys Val Cys Val 
            100                 105                 110


Leu Leu Val Leu Ala Leu Gly Leu Tyr Cys Gly Arg Ala Lys Pro Val 
        115                 120                 125


Ala Thr Ala Leu Glu Asp Leu Arg Ala Arg Leu Leu Gly Leu Val Leu 
    130                 135                 140


His Leu Arg His Val Ala Leu Thr Cys Trp Arg Gly Leu Leu Arg Leu 
145                 150                 155                 160


<210>  8658
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  8658
atgtgagatt ttattagaaa gaggattcga ctgctaacag ttgaggctcc ccaggctcac     60

ccaaagaccc ctccctcgtc ccagcaggaa ctcctgctgc tgctagggcc tggcccggcc    120

atcaccgtgt gcaccctctt gaggaggggg acacactgcc cgtgttcaag gggctgctcg    180

gaggaggcaa acccagcctt ttgcgattat ggcttgtggg gaatccagac ctcgaaaccc    240

cacggggagg gaagggtctg gttgtcaagg tgggtccctt tgatgtgagg tgccatcctc    300

tgagcccagg tctgaccccc ctctccagac cctacgtggg gggagggctg aacaaagcag    360

ggaggcccac ggttagacac caggcagaac tgcccaggag agacacaggg acaatcagac    420

cagcgtcctc gaggttagcc tgaggcgggt gggcacggcc gaccatccac ccggtggttc    480

ctgtttgtcc caccacttaa ctgggagaca ctgttttatt aaaacacacc gtggcttcct    540

tca                                                                  543


<210>  8659
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  8659

Gly Ser Pro Gly Ser Pro Lys Asp Pro Ser Leu Val Pro Ala Gly Thr 
1               5                   10                  15


Pro Ala Ala Ala Arg Ala Trp Pro Gly His His Arg Val His Pro Leu 
            20                  25                  30


Glu Glu Gly Asp Thr Leu Pro Val Phe Lys Gly Leu Leu Gly Gly Gly 
        35                  40                  45


Lys Pro Ser Leu Leu Arg Leu Trp Leu Val Gly Asn Pro Asp Leu Glu 
    50                  55                  60


Thr Pro Arg Gly Gly Lys Gly Leu Val Val Lys Val Gly Pro Phe Asp 
65                  70                  75                  80


Val Arg Cys His Pro Leu Ser Pro Gly Leu Thr Pro Leu Ser Arg Pro 
                85                  90                  95


Tyr Val Gly Gly Gly Leu Asn Lys Ala Gly Arg Pro Thr Val Arg His 
            100                 105                 110


Gln Ala Glu Leu Pro Arg Arg Asp Thr Gly Thr Ile Arg Pro Ala Ser 
        115                 120                 125


Ser Arg Leu Ala 
    130


<210>  8660
<211>  619
<212>  DNA
<213>  Homo sapiens

<400>  8660
aggattcgac tgctaacagt tgaggctccc caggctcacc caaagacccc tccctcgtcc     60

cagcaggaac tcctgctgct gctagggcct ggcccggcca tcaccgtgtg caccctcttg    120

aggaggggga cacactgccc gtgttcaagg ggctgctcgg aggaggcaaa cccagccttt    180

tgcgattatg gcttgtgggg aatccagacc tcgaaacccc acggggaggg aagggtctgg    240

ttgtcaaggt gggtcccttt gatgtgaggt gccatcctct gagcccaggt ctgacccccc    300

tacccagccc cgtgagtctg gagaggcccc agggaaggac ccctcatcag gggcggcttc    360

aggtgtagaa gccgagggga cagcaagggg cccagacacc cccgacccta cgtgggggga    420

gggctgaaca aagcagggag gcccacggtt agacaccagg cagaactgcc caggagagac    480

acagggacaa tcagaccagc gtcctcgagg ttagcctgag gcgggtgggc acggccgacc    540

atccacccgg tggttcctgt ttgtcccacc acttaactgg gagacactgt tttattaaaa    600

cacaccgtgg cttccttca                                                 619


<210>  8661
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  8661

Val Trp Arg Gly Pro Arg Glu Gly Pro Leu Ile Arg Gly Gly Phe Arg 
1               5                   10                  15


Cys Arg Ser Arg Gly Asp Ser Lys Gly Pro Arg His Pro Arg Pro Tyr 
            20                  25                  30


Val Gly Gly Gly Leu Asn Lys Ala Gly Arg Pro Thr Val Arg His Gln 
        35                  40                  45


Ala Glu Leu Pro Arg Arg Asp Thr Gly Thr Ile Arg Pro Ala Ser Ser 
    50                  55                  60


Arg Leu Ala 
65


<210>  8662
<211>  2035
<212>  DNA
<213>  Homo sapiens

<400>  8662
cgagaaggag ctgctgctgg cccggccgtc cccacgcacc tccttccaag aggagaagag     60

cgctgtcatt taggcacagt gcaggcaggg ggagctggcc ccgacctccc tgctgcgctc    120

gggggcacgg gcctgcctgg ggaagcagct ggggggctct gcctgggccc tggccacatg    180

cagccctgcg tgtgtcccct cgacgccacg tgtagtgagc cctgacccac tggacatggg    240

gactctttcc agtccggaga gctccttgtc tgtgtcccca gcagaaggtg gggtggctcc    300

tgcctcaccc tctgcccagc cctgatccag gccacagcca tctagggccc tgaaggaggg    360

gcaggaggca ggggtggctt ctggaacctg aggcttggcc ccggttgggt ctgttcttgg    420

gggctgcact gctggatccc aggagcaggt gtggaacagc cccatggcca gggtgatgga    480

aatcctcggc tgcatgcaga catagaccca ccctggactg ggctgtctcc ggagcccaga    540

cacatcgccc tgggaagggg cagctgggcc tgcagtgtgc tgggcagggg ctggcggccc    600

tggtcgtggg ctctccaggg tccctcaggg gattgggcct ctccccaggc aggaaggtgg    660

gaagtgcagg catgacccgg ggttcctgag gctggtccac caagttgctt ctgagacgcc    720

ttcgcttctg tcctggctgg ctgttaatga tatccctgtt ctaattccac tctggctaaa    780

ctgaaagtaa agatccttaa gcttacatgt gtctattcct caaaatcaaa ataaaaacaa    840

aagcacccga gtctccaaca gggatgagga ggagcgtgtg gggcttctgt ctgccctctc    900

cgctgttggc tggcctggct cgtggttcta actgtctgta atttgtgggt cacacacagt    960

ttgctcaggc tttgagcctt tcgtgtccga agcttttagg aattagaagt tggccttccc   1020

gaggttctgc cttcctctct gtacattttc tagtggcttc gagtctcact gcttcccatg   1080

cagcttcccc aggtgggagg atccatttcg aaggatctct tgggggtgtg gtgcccatct   1140

ttgagcaatg tttattcgaa aacacctgag gtcgtagcgt gggaccccgc aaagccaggc   1200

acgtccttgc gttgcctttg cagtggacag acagcagcgg ctgggggaga tcggcctgtg   1260

cggtgtcccc cgtcagaacc ggggctggag gggtgtccca agcacacagg gctgagcctg   1320

ggcctgtgac tgctctgaga gacccaacct ctgggagccg ctgcttctgc atccagaata   1380

tggggcagga acctgcccat cctccttcct ggggtggggt gggatgggct gggcctgggg   1440

agagatgctg gagggtcccc gggggagccc ccaccatggt cccttctggg ccacttctgg   1500

aaacagcccc ttttgttacc tccacccgca actctgggct ccctggattc caaagctgga   1560

agtgaccctg gagaccactt cacctgttcc ctggcacctg gagttgcagg gacacaccct   1620

gactgcaggg caaagggagc cggccgggca tccctcaaga cccaggggct tggtcagccc   1680

ctgcccgagt ggacacatcc actcccaggc ctgcaggaga tggggaggtt ccaggcgccc   1740

aggacatccg ctttggccac tgaggccgat tccttagcaa atcggttctg gtttctctca   1800

tttctataaa aacaccaaga ctgaaggaag ccacggtgtg ttttaataaa acagtgtctc   1860

ccagttaagt ggtgggacaa acaggaacca ccgggtggat ggtcggccgt gcccacccgc   1920

ctcaggctaa cctcgaggac gctggtctga ttgtccctgt gtctctcctg ggcagttctg   1980

cctggtgtct aaccgtgggc ctccctgctt tgttcagccc tccccccacg taggg        2035


<210>  8663
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  8663

Met Gly Trp Ala Trp Gly Glu Met Leu Glu Gly Pro Arg Gly Ser Pro 
1               5                   10                  15


His His Gly Pro Phe Trp Ala Thr Ser Gly Asn Ser Pro Phe Cys Tyr 
            20                  25                  30


Leu His Pro Gln Leu Trp Ala Pro Trp Ile Pro Lys Leu Glu Val Thr 
        35                  40                  45


Leu Glu Thr Thr Ser Pro Val Pro Trp His Leu Glu Leu Gln Gly His 
    50                  55                  60


Thr Leu Thr Ala Gly Gln Arg Glu Pro Ala Gly His Pro Ser Arg Pro 
65                  70                  75                  80


Arg Gly Leu Val Ser Pro Cys Pro Ser Gly His Ile His Ser Gln Ala 
                85                  90                  95


Cys Arg Arg Trp Gly Gly Ser Arg Arg Pro Gly His Pro Leu Trp Pro 
            100                 105                 110


Leu Arg Pro Ile Pro 
        115


<210>  8664
<211>  804
<212>  DNA
<213>  Homo sapiens

<400>  8664
cgagaaggag ctgctgctgg cccggccgtc cccacgcacc tccttccaag aggagaagag     60

cgctgtcatt taggcacagt gcaggcaggg ggagctggcc ccgacctccc tgctgcgctc    120

gggggcacgg gcctgcctgg ggaagcagct ggggggctct gcctgggccc tggccacatg    180

cagccctgcg tgtgtcccct cgacgccacg tgtagtgagc cctgacccac tggacatggg    240

gactctttcc agtccggaga gctccttgtc tgtgtcccca gcagaaggtg gggtggctcc    300

tgcctcaccc tctgcccagc cctgatccag gccacagcca tctagggccc tgaaggaggg    360

gcaggaggca ggggtggctt ctggaacctg aggcttggcc ccggttgggt ctgttcttgg    420

gggctgcact gctggatccc aggagcaggt gtggaacagc cccatggcca gggtgatgga    480

aatcctcggc tgcatgcaga catagaccca ccctggactg ggctgtctcc ggagcccaga    540

cacatcgccc tgggaagggg cagctgggcc tgcagtgtgc tgggcagggg ctggcggccc    600

tggtcgtggg ctctccaggg tccctcaggg gattgggcct ctccccaggc aggaaggtgg    660

gaagtgcagg catgacccgg ggttcctgag gctggtccac caagttgctt ctgagacgcc    720

ttcgcttctg tcctggctgg ctgttaatga tatccctgtt ctaattccac tctggctaaa    780

ctgaaagtaa agatccttaa gctt                                           804


<210>  8665
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  8665

Ala Leu Thr His Trp Thr Trp Gly Leu Phe Pro Val Arg Arg Ala Pro 
1               5                   10                  15


Cys Leu Cys Pro Gln Gln Lys Val Gly Trp Leu Leu Pro His Pro Leu 
            20                  25                  30


Pro Ser Pro Asp Pro Gly His Ser His Leu Gly Pro 
        35                  40


<210>  8666
<211>  1207
<212>  DNA
<213>  Homo sapiens

<400>  8666
ccagaggctg gaaggtgccg tgagctcctc cccacacgca gcctctgcct ggatggcaga     60

attcatgcag aattcgttca gggctaagtg acatctggcc acccctgggc cagctggcat    120

ggagacagca tccggccagg gttgggggag acaagctgga cgccctccac ataggctggc    180

cagtcaggtc ctactgggac agccaagggg ccctgtgcga ggcctggagg tgccccccgc    240

ccccgcccca cacccatagt ctctctgcac catcctcatc agggagccgg cacccaccca    300

gtccactgcc aggctcacag gtgggcactg gggcgctcac ctcactacac gtggcgtcga    360

ggggacacac gcagggctgc atgtggccag ggcccaggca gagcccccca gctgcttccc    420

caggcaggcc cgtgcccccg agcgcagcag ggaggtcggg gccagctccc cctgcctgca    480

ctgtgcctaa atgacagcgc tcttctcctc ttggaaggag gtgcgtgggg acggccgggc    540

cagcagcagc tccttctcgt ggatcaggct gtccagcagg tcctcctgac ggtagttgtg    600

gtagaccttc aggaaggcca gcgtggtgat ggccagccag gccagccatg aggcccagag    660

gccaaactgg gcaattgcaa actgatcgta gaaggcggag ttgtccacgc ccagctccaa    720

gtcgatgtcc tggagctctt cacagctgtg gggtacggtg cccttctcgg tgatggtgtc    780

gcaccacatg gtgaagccca cgctcacgat ggtgctggca atgaagacca ggaagaccac    840

gaaggcgctg accaggaggt tcaggaaggc ggagaagaag gagccctcgt gtcccttgca    900

gaggaagaag agcgtgcgcc aggcgtgcgc ggcggccagc agcagagaca ggaggctggc    960

gagcaggctg aagcggcagg cggccggcgg gccccactcc tgcaccgtga agcgctcgcg   1020

ctcctgcacc gtgaggttgg cgctcagcca catgccctcg gtgaagagca ggcagcggcc   1080

gcggaagtcg tggccgttct cggacagcgg gaccaccacc acgaagctga acaggaaggc   1140

caagaagtag caggcgcact gagcgaaaag gaaattgttg agcgccatgg ccggcccggg   1200

cgagagc                                                             1207


<210>  8667
<211>  141
<212>  PRT
<213>  Homo sapiens

<400>  8667

Met Ser Trp Ser Ser Ser Gln Leu Trp Gly Thr Val Pro Phe Ser Val 
1               5                   10                  15


Met Val Ser His His Met Val Lys Pro Thr Leu Thr Met Val Leu Ala 
            20                  25                  30


Met Lys Thr Arg Lys Thr Thr Lys Ala Leu Thr Arg Arg Phe Arg Lys 
        35                  40                  45


Ala Glu Lys Lys Glu Pro Ser Cys Pro Leu Gln Arg Lys Lys Ser Val 
    50                  55                  60


Arg Gln Ala Cys Ala Ala Ala Ser Ser Arg Asp Arg Arg Leu Ala Ser 
65                  70                  75                  80


Arg Leu Lys Arg Gln Ala Ala Gly Gly Pro His Ser Cys Thr Val Lys 
                85                  90                  95


Arg Ser Arg Ser Cys Thr Val Arg Leu Ala Leu Ser His Met Pro Ser 
            100                 105                 110


Val Lys Ser Arg Gln Arg Pro Arg Lys Ser Trp Pro Phe Ser Asp Ser 
        115                 120                 125


Gly Thr Thr Thr Thr Lys Leu Asn Arg Lys Ala Lys Lys 
    130                 135                 140


<210>  8668
<211>  1623
<212>  DNA
<213>  Homo sapiens

<400>  8668
ccaaacagtt gaaggagaaa caatttaatc agaaccaggc ctgagctaca ttaagctgat     60

tctcatttga gcgtatttgc catcagactg cactcacacc ttaatccaac tggcacaaat    120

taggcctgag gcctcttcca ctcactaaat ttgcatgaag gtgtctttga caggtccagt    180

tcatctcggc aaagagcatt caggcccacc catgtccagc acccttggag ggctcctggc    240

caggagaagc gtcctcaggc cagccacggc cagcaagagc cttcagaggc cagcctgggg    300

tccggaattg gacctgaagc cagcgggccc tgatcagtgc tggcaggagc caggtgtctg    360

gtctcagcca cccccacccg gcacccctca tctgcctcat ctccgtctgg ggcacatctg    420

cagatttcaa ggggcaaacc caattccagg gttccccctc cggccctcac gggccactga    480

tgtgtcccca catgcctgca tttcagcaaa tagcgtccct cagagtgggg gccaccatcg    540

ccctccacca agtctcctag ggggcggggg acgcagctta tacaagggca gggtggcaaa    600

tctgaattca caagtgggat cccctgcctc cttccttgga ctctgtatca gcttccccct    660

ggctagggga ctcctctaag cctccagctc tgatctgaac aggcccaccc agcgccagca    720

ccaaagtcca aagcccttgt ccctacactg gacccccagg atctgatgcc tggtttcgtt    780

tctggcacca cctcccccca cacccccaca cttcccaccc cagaccccag ggccttgcca    840

cttcctgatt ctaactcact gtggccatct cctccccaaa cccacctaca aaagcccagc    900

tctcccccac ctcctgcagg aagccttccc gactgctccc actgcctggt cccattgcta    960

actaccttat ccacacagga gcctgcctcc tcctctggat gggggagagc tcagcaaatg   1020

tccagcagta aatggccccc tcccagcatt gcaagcctcc cttcttgccc agagccccct   1080

acctgggcaa ttgcaaactg atcgtagaag gcggagttgt ccacgcccag ctccaagtcg   1140

atgtcctgga gctcttcaca gctgtggggt acggtgccct tctcggtgat ggtgtcgcac   1200

cacatggtga agcccacgct cacgatggtg ctggcaatga agaccaggaa gaccacgaag   1260

gcgctgacca ggaggttcag gaaggcggag aagaaggagc cctcgtgtcc cttgcagagg   1320

aagaagagcg tgcgccaggc gtgcgcggcg gccagcagca gagacaggag gctggcgagc   1380

aggctgaagc ggcaggcggc cggcgggccc cactcctgca ccgtgaagcg ctcgcgctcc   1440

tgcaccgtga ggttggcgct cagccacatg ccctcggtga agagcaggca gcggccgcgg   1500

aagtcgtggc cgttctcgga cagcgggacc accaccacga agctgaacag gaaggccaag   1560

aagtagcagg cgcactgagc gaaaaggaaa ttgttgagcg ccatggccgg cccgggcgag   1620

agc                                                                 1623


<210>  8669
<211>  196
<212>  PRT
<213>  Homo sapiens

<400>  8669

Met Ala Pro Ser Gln His Cys Lys Pro Pro Phe Leu Pro Arg Ala Pro 
1               5                   10                  15


Tyr Leu Gly Asn Cys Lys Leu Ile Val Glu Gly Gly Val Val His Ala 
            20                  25                  30


Gln Leu Gln Val Asp Val Leu Glu Leu Phe Thr Ala Val Gly Tyr Gly 
        35                  40                  45


Ala Leu Leu Gly Asp Gly Val Ala Pro His Gly Glu Ala His Ala His 
    50                  55                  60


Asp Gly Ala Gly Asn Glu Asp Gln Glu Asp His Glu Gly Ala Asp Gln 
65                  70                  75                  80


Glu Val Gln Glu Gly Gly Glu Glu Gly Ala Leu Val Ser Leu Ala Glu 
                85                  90                  95


Glu Glu Glu Arg Ala Pro Gly Val Arg Gly Gly Gln Gln Gln Arg Gln 
            100                 105                 110


Glu Ala Gly Glu Gln Ala Glu Ala Ala Gly Gly Arg Arg Ala Pro Leu 
        115                 120                 125


Leu His Arg Glu Ala Leu Ala Leu Leu His Arg Glu Val Gly Ala Gln 
    130                 135                 140


Pro His Ala Leu Gly Glu Glu Gln Ala Ala Ala Ala Glu Val Val Ala 
145                 150                 155                 160


Val Leu Gly Gln Arg Asp His His His Glu Ala Glu Gln Glu Gly Gln 
                165                 170                 175


Glu Val Ala Gly Ala Leu Ser Glu Lys Glu Ile Val Glu Arg His Gly 
            180                 185                 190


Arg Pro Gly Arg 
        195


<210>  8670
<211>  702
<212>  DNA
<213>  Homo sapiens

<400>  8670
gcatgaaggt gtctttgaca ggtccagttc atctcggcaa agagcattca ggcccaccca     60

tgtccagcac ccttggaggg ctcctggcca ggagaagcgt cctcaggcca gccacggcca    120

gcaagagcct tcagaggcca gcctggggtc cggaattgga cctgggcaat tgcaaactga    180

tcgtagaagg cggagttgtc cacgcccagc tccaagtcga tgtcctggag ctcttcacag    240

ctgtggggta cggtgccctt ctcggtgatg gtgtcgcacc acatggtgaa gcccacgctc    300

acgatggtgc tggcaatgaa gaccaggaag accacgaagg cgctgaccag gaggttcagg    360

aaggcggaga agaaggagcc ctcgtgtccc ttgcagagga agaagagcgt gcgccaggcg    420

tgcgcggcgg ccagcagcag agacaggagg ctggcgagca ggctgaagcg gcaggcggcc    480

ggcgggcccc actcctgcac cgtgaagcgc tcgcgctcct gcaccgtgag gttggcgctc    540

agccacatgc cctcggtgaa gagcaggcag cggccgcgga agtcgtggcc gttctcggac    600

agcgggacca ccaccacgaa gctgaacagg aaggccaaga agtagcaggc gcactgagcg    660

aaaaggaaat tgttgagcgc catggccggc ccgggcgaga gc                       702


<210>  8671
<211>  232
<212>  PRT
<213>  Homo sapiens

<400>  8671

Met Lys Val Ser Leu Thr Gly Pro Val His Leu Gly Lys Glu His Ser 
1               5                   10                  15


Gly Pro Pro Met Ser Ser Thr Leu Gly Gly Leu Leu Ala Arg Arg Ser 
            20                  25                  30


Val Leu Arg Pro Ala Thr Ala Ser Lys Ser Leu Gln Arg Pro Ala Trp 
        35                  40                  45


Gly Pro Glu Leu Asp Leu Gly Asn Cys Lys Leu Ile Val Glu Gly Gly 
    50                  55                  60


Val Val His Ala Gln Leu Gln Val Asp Val Leu Glu Leu Phe Thr Ala 
65                  70                  75                  80


Val Gly Tyr Gly Ala Leu Leu Gly Asp Gly Val Ala Pro His Gly Glu 
                85                  90                  95


Ala His Ala His Asp Gly Ala Gly Asn Glu Asp Gln Glu Asp His Glu 
            100                 105                 110


Gly Ala Asp Gln Glu Val Gln Glu Gly Gly Glu Glu Gly Ala Leu Val 
        115                 120                 125


Ser Leu Ala Glu Glu Glu Glu Arg Ala Pro Gly Val Arg Gly Gly Gln 
    130                 135                 140


Gln Gln Arg Gln Glu Ala Gly Glu Gln Ala Glu Ala Ala Gly Gly Arg 
145                 150                 155                 160


Arg Ala Pro Leu Leu His Arg Glu Ala Leu Ala Leu Leu His Arg Glu 
                165                 170                 175


Val Gly Ala Gln Pro His Ala Leu Gly Glu Glu Gln Ala Ala Ala Ala 
            180                 185                 190


Glu Val Val Ala Val Leu Gly Gln Arg Asp His His His Glu Ala Glu 
        195                 200                 205


Gln Glu Gly Gln Glu Val Ala Gly Ala Leu Ser Glu Lys Glu Ile Val 
    210                 215                 220


Glu Arg His Gly Arg Pro Gly Arg 
225                 230


<210>  8672
<211>  3816
<212>  DNA
<213>  Homo sapiens

<400>  8672
ctggatcttc ctgccttgac agccccacag aaaatgctaa gagcccagga aggttgtgaa     60

gggtgtgtgt gtgtttgtgt gtgtgtctgt gtgctgtgtg tgtctgtgtg tgtttgtgtg    120

tgtctgtgtg tttgtgtgtg tgtatgtgtg tgtctgtgtt tgtgtgtgtt gtctgtgtct    180

gtgtgtctgt gtgtctgtgt gtctgtgtgt ctgtgtgtgt gtcttgtgtc tgtgtgtttg    240

tgtgtgtgtc tgtgtgtttg tgtgtctgtg tgtttgtgtg tgtgtttgca tctgtgtgtt    300

tgtgtgtctg tgtgtgtgtg tgtttgtgtt tgtgtgtctg tgtgtgtttg tgtgtctgtg    360

tgtgtttgca tctgtgtgtg tgtgtgggtt tgtgtgtgtc tgtgtgtttc tgtgtgtctg    420

tgtgtgtgtg tctgtgtgtg tgtgtttgca tctgtgtgtt tgtgtgtgtg tgggtttgtg    480

tgtgtctgtg tgtttgtgtg tgtctgtgtg tgtgtctgtg tttgtgtgtg tttctgtgtg    540

tctgtgtgtt tgtgtcggtg tgtgtctctg tgtgtgtttg tgtgtgtatg tgtattggga    600

ggacagtggt cccagctcct caggggcatc aggctctgta gcagggccca ccgtctcggc    660

aggagggtgc aatggcctca cccacactgt ccaggcagtt ctcttgggac cccttttagc    720

cagcacaggt gccttctccc tcggcaggag ggtgcgatgg tctcacccac acggtccagg    780

cgggtctctt gggtctcctt ttccagcaca ggtgccttct ccctaggaaa cggcaaagat    840

gtaatgacca cactcaggtg taaactctgt agccgggttt ctaaactaga acctactgat    900

cgtgggataa aaatcaggaa acggtgaaga tgtaataacc acactcaggt gtaaactctg    960

cagccggatt tctaaactag aagctactga tcatgggata aaaatcagga aacggtgaag   1020

atgtaatcac cacactcagg tgtaaactct gcagccgggt tctaaactag aacctactga   1080

tcatgggatt caggtgtccc tgaacttgga tggaaaaacg ttgcatcttt actttcacca   1140

gcctctaggc taaagtgagt gttcctcaat agtgaatgtg gccaaaggac ctagcggtct   1200

ccacagaacc tgggactcca ccgtcagcaa agtcctgtgt attttcccat cgtgtttcag   1260

ttgcttcggc gtcttgaagc ctcatttttg ttcctgcttc aacactgttg gtcatgagag   1320

ctgctgctag atctggatca gtaggttttt tttaatctgt tgcccaggct gtagtgcagt   1380

ggtgcaatct cggttcactg caacctccgc ctcccaggtt caagtgattc tcctgcctca   1440

gcctcccaag tagctgggag tacaggtgca cgccaccaca cccagctgat ttttgtattt   1500

ttagtagaga tggtggcggg gggggagggg tctcaccatg ttggccagcc tggtcttgaa   1560

cccctgacct caggtgatcc acccgcctcg gcctcccaaa gtgctgagat tacaggcgtg   1620

agccaccatg cctggcctga atcagtagat taacaagaaa tccaataaca attactttat   1680

tattttggta accgtatttc aatatagtgg gtgtatgagt tggttctcac actgctataa   1740

agatactaca agagactggg taatttataa tcaaaggagg ttttatttat ttactgagac   1800

agagtcttgt tttgtccccc aggctggagt gcagtggtgc aatctcagct cactgcaacc   1860

tccgcctcct ggtttcaagt gagtctcctg cctcagcctc ccaagtaact gggattacag   1920

gtgcgtgcca ccatgcccgg ctaatttttg tatttttagt aggacggggt ttcaccacgt   1980

tggccaggct ggtctcgaac tcctgacctc aagtgatcca cccacctcag cctcccaaag   2040

tgctggtatc acaggtgtga gccacctcgc ccagcccaca aaggaggttt aattgactca   2100

cagttctgca tggctgggga ggcctcagga aacttacaat catggtggaa gggaagcagg   2160

tgccttctca caaggcggca cgagaaagaa gttcaagcag gggaaatgcc agctgaagcc   2220

tgggcgcagg tgaccacgca ggccgagagg tcccacgccc gcgaagaccc agggaagctg   2280

gtggtgcagt gcggtctgag tccgaagccc tgagagccgg agggctaatg gcgttaatct   2340

cagtgtcagg gccagagaag gtgaggtgag tgtcccagct caagcagcgt ggcaggaaga   2400

ggggggcaaa ttcacctttc tctgccttcc gcgctattcg ggtcctcagc ggattgggtg   2460

acaccaccca ccctggggag ggcggcctgc tttacagagc ccactgattc aaatgctaat   2520

ctcatccaga acaccctcgg acatccccag aaataacgtt caacccggca ccccacggcc   2580

aggggagctg acacataaag ttaaccgtca ctccgcccgc atggagaggg agcccacagg   2640

aaggagctgg tgctgctgtc tcgaccctga ccctgggccg tgtgggtcgt tctggccctt   2700

gcccctgctt gtctgtagct cccaccccac agtgaggaac ctgccccacc acccaccatc   2760

catggaccta atcgctaagc tgcagtgtgc agggggagca gtgtagggac tgctcacctg   2820

taccccgcgg cagaagcgtg tgtctgccag ggtacagggc tcatgtgcgg gtccatttgc   2880

ttttggcttc acagacttcg tcgtttgtga gggtacccag gtcagcccca tcccccagcc   2940

cctccctacg tctgtaatac agctgctccc tgggtctgtg atacagccag aggctctcgc   3000

cacacacggc ccgccttccg tcctagaccc ccagcctctt gactgagctt taaaatttgc   3060

atacattaag gctcactctt gctgtgaagt tctgtgggtt ttgacagatg cacagtgtcg   3120

tgtctctgcc attacaatgt cgttcacgtt agtttcacag ccctaaaaac ccccctgtgc   3180

tccaccgatc caaccatttc ctctttcccg aactcctggc aacaactgtt tccataaatg   3240

tatttttctg gtgggttttt ggtgaacaat tttatcaaat tagaaatatt tcatttgttt   3300

caatttctaa tttgcccaga aatttttaaa aagtcaccga tggcatcact tgagacattg   3360

ggacactttt tgccctgtca tctattcaga tggtatttgc acggatcaga ttctgatatt   3420

aaaccttcct tgaattcctg ggagaaaccc ttagatctat cagggtccca gcaggaaaga   3480

gacccacatt tagagcaggt tacttgcagc agtgtttaac aaaggggctc tttataaagg   3540

tagggcagag tactggaaac ctcaaggggc agtacatgtc ccagggctgg ccaaaggcat   3600

gcctggtgga gagaattttc tggaatgtga aggagagtgc tgtggagagg agccatgaca   3660

ttcccaaggc cacctcacac agtcatctgc catcatttgc agatcacatg tcagcttact   3720

tagcaagcct aacagaacgg acaggaaaac gtaatgttat aaacacataa ttctccccag   3780

agaattatgg ggacataata aattcaatgc aattct                             3816


<210>  8673
<211>  297
<212>  PRT
<213>  Homo sapiens

<400>  8673

Met Leu Arg Ala Gln Glu Gly Cys Glu Gly Cys Val Cys Val Cys Val 
1               5                   10                  15


Cys Val Cys Val Leu Cys Val Ser Val Cys Val Cys Val Cys Leu Cys 
            20                  25                  30


Val Cys Val Cys Val Cys Val Cys Leu Cys Leu Cys Val Leu Ser Val 
        35                  40                  45


Ser Val Cys Leu Cys Val Cys Val Ser Val Cys Leu Cys Val Cys Leu 
    50                  55                  60


Val Ser Val Cys Leu Cys Val Cys Leu Cys Val Cys Val Ser Val Cys 
65                  70                  75                  80


Leu Cys Val Cys Leu His Leu Cys Val Cys Val Ser Val Cys Val Cys 
                85                  90                  95


Val Cys Val Cys Val Ser Val Cys Val Cys Val Ser Val Cys Val Cys 
            100                 105                 110


Ile Cys Val Cys Val Trp Val Cys Val Cys Leu Cys Val Ser Val Cys 
        115                 120                 125


Leu Cys Val Cys Val Cys Val Cys Val Phe Ala Ser Val Cys Leu Cys 
    130                 135                 140


Val Cys Gly Phe Val Cys Val Cys Val Phe Val Cys Val Cys Val Cys 
145                 150                 155                 160


Val Cys Val Cys Val Cys Phe Cys Val Ser Val Cys Leu Cys Arg Cys 
                165                 170                 175


Val Ser Leu Cys Val Phe Val Cys Val Cys Val Leu Gly Gly Gln Trp 
            180                 185                 190


Ser Gln Leu Leu Arg Gly Ile Arg Leu Cys Ser Arg Ala His Arg Leu 
        195                 200                 205


Gly Arg Arg Val Gln Trp Pro His Pro His Cys Pro Gly Ser Ser Leu 
    210                 215                 220


Gly Thr Pro Phe Ser Gln His Arg Cys Leu Leu Pro Arg Gln Glu Gly 
225                 230                 235                 240


Ala Met Val Ser Pro Thr Arg Ser Arg Arg Val Ser Trp Val Ser Phe 
                245                 250                 255


Ser Ser Thr Gly Ala Phe Ser Leu Gly Asn Gly Lys Asp Val Met Thr 
            260                 265                 270


Thr Leu Arg Cys Lys Leu Cys Ser Arg Val Ser Lys Leu Glu Pro Thr 
        275                 280                 285


Asp Arg Gly Ile Lys Ile Arg Lys Arg 
    290                 295


<210>  8674
<211>  1317
<212>  DNA
<213>  Homo sapiens

<400>  8674
ctggggggtg gcaccaggct gtgaaggatc cacagactgg catatgcagg aggaaatggg     60

gcgggcgagg agtaaggacc ccaaaaagca ggggtaggga agggccctcc cagcgcccca    120

ctgtaatagg ggcctcatca atgccccatg ctcactgaat aaagcactgc cagcgaaagg    180

tgaaaagagg aacaaagaac attctcctgg acgccaccca cagaaagcca cgtgcaggct    240

tggccctcac cttggggacc ttggacacgg agctggttat gtcacatctg gctctcagag    300

ctggggcagc gtctaggagg cctgatgtag aaagcactca gctaagccct agttaccggc    360

acacgggcac cagcgccccc tctcagcaaa ctccacgtct tatgaaatta gcactggatt    420

tccacttcaa ttggaaaata tggccaaggt ggagaacccc ttctttaagc aaaagatggc    480

acggaccccc gacataagac agttcaaagc tgagcggctc tccccatcat gcaagtaacc    540

tgcgtgccgc cacgggaaac agcacgcatc ccatctggac tcccaccaga caactgaggc    600

aaccgagaag gaggctgggg agggacagct cgagggctca ctggaggtca gcagggaggt    660

ggactgcgtc tcccgagggc cagcactggc ttagcctgct cagtgaggtg cccgaaggag    720

gcccaccagc tctgccagca cccggcctct gcacctcagc tttcagcgga taggtttgtg    780

caacgaaata tttcatagaa atcaagaaac atgagtgaac gatgcacacc accgcgtgga    840

tgagtctcag agactgtgga gcgaaagaag ccagacacaa aggttgacat ttacacgcaa    900

tcctagaatg acggctctat ggtggcagag aggagaaaag cagttagctt tggcaggtgc    960

ccacggaggg ggctatgcaa tggaactttc tgggccctgg aggtgttgca gagtttgcta   1020

tgggtggtgg tagttacgtg ggtttctatg aatgtaaaaa ctcttggtgt ggtagaccca   1080

agctctgggc acctcacgca tgccatgcag cagctcgatc tgtgacagcg agtcctgtgt   1140

tccatgatat ggctgcaaac acttgacaga gtgaatgccg aacctctgct cctaagggaa   1200

atagagggcc aggttcctac gagcctctgc tccagccttt tcagcaacca atcagtacac   1260

aatagagtta tttatgtgtt tctgttaata tatgtcacta aactcccggc caagagc      1317


<210>  8675
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  8675

Met Ser His Leu Ala Leu Arg Ala Gly Ala Ala Ser Arg Arg Pro Asp 
1               5                   10                  15


Val Glu Ser Thr Gln Leu Ser Pro Ser Tyr Arg His Thr Gly Thr Ser 
            20                  25                  30


Ala Pro Ser Gln Gln Thr Pro Arg Leu Met Lys Leu Ala Leu Asp Phe 
        35                  40                  45


His Phe Asn Trp Lys Ile Trp Pro Arg Trp Arg Thr Pro Ser Leu Ser 
    50                  55                  60


Lys Arg Trp His Gly Pro Pro Thr 
65                  70


<210>  8676
<211>  1694
<212>  DNA
<213>  Homo sapiens

<400>  8676
cgccccgcgc ccgccaggag ccaccgtccg agccttgcgg agcgcggcag tgggcgccgg     60

ctgcccgcag cccctgaccc ggccccggac ggagcgccgg ccgcaccacc gccctctggc    120

cgttgcctca ccggctcggc aagatgtcgg tgaaggaggg cgcacagcgc aagtgggcag    180

cgctgaagga gaagctgggg ccacaggatt cggaccccac ggaggccaac ctggagagcg    240

cggaccccga gctgtgcatc cggctgctcc agatgccctc tgtggtcaac tactccggcc    300

tgcgcaagcg cctggagggc agcgacggcg gctggatggt gcagttcctg gagcagagcg    360

gcctggacct gctgctggag gcgctggcgc ggctgtcggg ccgcggcgtt gcacgtatct    420

ccgacgccct gctgcagctc acctgcgtca gctgcgtgcg cgccgtcatg aactcgcggc    480

agggcatcga gtacatcctc agcaaccagg gctacgtgcg ccagctctcc caggccctgg    540

acacatccaa cgtgatggtg aagaagcagg tgtttgagct actggctgcc ctgtgcatct    600

actctcccga gggccacgtg ctgaccctgg acgccctgga ccactacaag acggtgtgca    660

gccagcagta ccgcttcagc attgtcatga acgagctctc cggcagcgac aacgtgccct    720

acgtggtcac cctgcttagc gtgatcaacg ccgtcatctt gggccccgag gacctgcgcg    780

cgcgcaccca gctgcggaac gagtttatcg ggctgcagct gctggacgtc ctggctcgcc    840

tgcggtgagt ccccactgta gcggtcctgc cggctccccc tcctgctccc aaggccaggc    900

ccacctgccc tttggctccc agccacctca cctaagcagc acctccagat ggcagggagg    960

tggctccctc ggagtaaccc caggggtcca gccagaagcc aggtctcagg ctagaatcca   1020

gctcactgtc cctggcagct gcccacagaa actagggttg cagcagccat agaaaggaca   1080

gaatgagctc atatcctttg cacaccgtgg atggagctgg aggccgtgat cctaagtgaa   1140

ccaacccaga aacagaaaat gaaatgccaa taagagggaa ctacagggtg gttcacgtgg   1200

acgcaagatg gagacaggga cacgggctcc agggcgagag ttgaaaaact acctacaggg   1260

tacagtgttc gtcgctactt ggtgtcaggc ccactagaac aagggtcccc aaccgccagg   1320

ctgcggaccg gtacctggcc tattggaacc gggccacgca gcaggaagtg agcggtgggc   1380

gggcattcct gcctgagctg cacctcatgt cagatcagca ctgcattaga ttctccagcg   1440

cacgcacgcg cgcaagggat ccaggctgcg cgctcctcat gacaatctaa tgcctgatga   1500

tcgggggtgg aacagtttta tccctaaacc attcccgtca ccccagtcta tggaaaaatt   1560

gtcttccaca aaaccagtcc ctggtgccaa aaaggctggg gaccactgcc ctagaaggca   1620

aatcgcctac gttacacagt gtaccatgtg gcaaacacgc acatgtaccc ccgagtctaa   1680

aataaaaatt tttt                                                     1694


<210>  8677
<211>  234
<212>  PRT
<213>  Homo sapiens

<400>  8677

Met Ser Val Lys Glu Gly Ala Gln Arg Lys Trp Ala Ala Leu Lys Glu 
1               5                   10                  15


Lys Leu Gly Pro Gln Asp Ser Asp Pro Thr Glu Ala Asn Leu Glu Ser 
            20                  25                  30


Ala Asp Pro Glu Leu Cys Ile Arg Leu Leu Gln Met Pro Ser Val Val 
        35                  40                  45


Asn Tyr Ser Gly Leu Arg Lys Arg Leu Glu Gly Ser Asp Gly Gly Trp 
    50                  55                  60


Met Val Gln Phe Leu Glu Gln Ser Gly Leu Asp Leu Leu Leu Glu Ala 
65                  70                  75                  80


Leu Ala Arg Leu Ser Gly Arg Gly Val Ala Arg Ile Ser Asp Ala Leu 
                85                  90                  95


Leu Gln Leu Thr Cys Val Ser Cys Val Arg Ala Val Met Asn Ser Arg 
            100                 105                 110


Gln Gly Ile Glu Tyr Ile Leu Ser Asn Gln Gly Tyr Val Arg Gln Leu 
        115                 120                 125


Ser Gln Ala Leu Asp Thr Ser Asn Val Met Val Lys Lys Gln Val Phe 
    130                 135                 140


Glu Leu Leu Ala Ala Leu Cys Ile Tyr Ser Pro Glu Gly His Val Leu 
145                 150                 155                 160


Thr Leu Asp Ala Leu Asp His Tyr Lys Thr Val Cys Ser Gln Gln Tyr 
                165                 170                 175


Arg Phe Ser Ile Val Met Asn Glu Leu Ser Gly Ser Asp Asn Val Pro 
            180                 185                 190


Tyr Val Val Thr Leu Leu Ser Val Ile Asn Ala Val Ile Leu Gly Pro 
        195                 200                 205


Glu Asp Leu Arg Ala Arg Thr Gln Leu Arg Asn Glu Phe Ile Gly Leu 
    210                 215                 220


Gln Leu Leu Asp Val Leu Ala Arg Leu Arg 
225                 230


<210>  8678
<211>  709
<212>  DNA
<213>  Homo sapiens

<400>  8678
ataacttttc caacccagga agtaactgca ctttgatgga aggcgcagag tctatttcag     60

agtgcagatg tggaaactga ggccggaaga gggcgagtat cctgctccat tccagtgcca    120

gacggagggg cagggctggc agtaagggaa tttcctacgt ccagcgcctt ctgggtgtgc    180

ctgacctctg gcccggttcc tgggttcctg gttccctgcc tgggcagggt ctctgcctct    240

ctgcctcctg gtgtgtccag ctggagtggg cagtaatgct gtggtcacag ctgagctgcg    300

ggagccctgg gtggggagct tgagccccag aaggcccaga cagacagacc accccccacg    360

cctgtgctcc ccagggggca ttggggacgg tcagggacac agctggtcac cccgccttcc    420

cctccttagt catggtcact cctggggcga ctccccagtt agagggttga cgggtgggtc    480

tgggggcgta cagggattgg atcctacccc acccaaaagg aacagagagc tgtgatggag    540

gctgattccc ctaagcctgc cagcggttgc ggggtgggaa gggctccctg tgcgcccacc    600

tgcgcgtggg cagctggaag ccaagcagtc agggtggggc cgcaggccgg cgcgcacctc    660

ggggtgccac ccgggcggcg gacccgaagt tgaagtttat tttcccaac                709


<210>  8679
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  8679

Met Glu Ala Asp Ser Pro Lys Pro Ala Ser Gly Cys Gly Val Gly Arg 
1               5                   10                  15


Ala Pro Cys Ala Pro Thr Cys Ala Trp Ala Ala Gly Ser Gln Ala Val 
            20                  25                  30


Arg Val Gly Pro Gln Ala Gly Ala His Leu Gly Val Pro Pro Gly Arg 
        35                  40                  45


Arg Thr Arg Ser 
    50


<210>  8680
<211>  3008
<212>  DNA
<213>  Homo sapiens

<400>  8680
cactactgcc ctgcacctgc agcccccccg tggcgggagg catggaggag gtcatcgtgg     60

cccaggtgga ccatggcttg ggctcagcat gggtccccag ccatcggcgg gtgaacccac    120

ccacactgcg catgaagaag ctgaactggc agaagctgcc atccaacgtg gcacgtgagc    180

acaactctat gtgggcgtcc ctgagcagcc ccgacgccga ggctgtggag cccgacttct    240

ccagcatcga gcgactattc tccttccctg cagccaagcc caaggagccc accatggtgg    300

ccccccgggc caggaaggag cccaaggaga tcactttcct cgatgccaag aagagcctga    360

acctcaacat cttcctgaag caatttaagt gctccaacga ggaggtcgct gctatgatcc    420

gggctggaga taccaccaag tttgatgtgg aggttctcaa acaactcctt aagctccttc    480

ccgagaagca cgagattgaa aacctgcggg cattcacaga ggagcgagcc aagctggcca    540

gcgccgacca cttctacctc ctcctgctgg ccattccctg ctaccagctg cgaatcgagt    600

gcatgctgct gtgtgagggc gcggccgccg tgctggacat ggtgcggccc aaggcccagc    660

tggtgctggc tgcctgcgaa agcctgctca ccagccgcca gctgcccatc ttctgccagc    720

tgatcctgag aattgggaac ttcctcaact acggcagcca caccggtgac gccgacggct    780

tcaagatcag cacattgctg aagctcacgg agaccaagtc ccagcagaac cgcgtgacgc    840

tgctgcacca cgtgctggag gaagcggaaa agagccaccc cgacctcctg cagctgcccc    900

gggacctgga acagccctcg caagcagcag ggatcaacct ggagatcatc cgctcagagg    960

ccagctccaa cctgaagaag cttctggaga ccgagcggaa ggtgtctgcc tccgtggccg   1020

aggtccagga gcagtacacc gagcgcctcc aggcaacatc tcggccttcc gggcactgga   1080

tgagctgttt gaggccatcg agcagaagca acgggagctg gccgactacc tgtgtgagga   1140

cgcccagcag ctgtccctgg aggacacgtt cagcaccatg aaggctttcc gggacctttt   1200

cctccgcgcc ctgaaggaga acaaggaccg gaaggagcag gcggcgaagg cagagaggag   1260

gaagcagcag ctggcggagg aggaggcgcg gcggcctcgg ggagaggacg ggaagcctgt   1320

caggaagggg cccgggaagc aggaggaggt gtgtgtcatc gatgccctgc tggctgacat   1380

caggaagggc ttccagctgc ggaagacagc ccggggccgc ggggacaccg acgggggcag   1440

caaggcagcc tccatggatc ccccaagagc cacagagcct gtggccacca gtaaccctgc   1500

aggagatccc gtgggcagca cgcgctgtcc cgcctctgag cccggccttg atgctacaac   1560

agccagcgag tcccggggct gggaccttgt agacgccgtg acccccggcc ctcagcccac   1620

cctggagcag ttggaggagg gtggtccacg gcccctggag aggcgttctt cctggtatgt   1680

ggatgccagc gatgtcctaa ccactgagga tccccagtgc ccccagccct tggagggggc   1740

ctggccggtg actctgggag atgctcaggc cctgaagccc ctcaagttct ccagcaacca   1800

gccccctgca gccggaagtt caaggcaaga tgccaaggat cccacgtcct tgctgggcgt   1860

cctccaggcc gaggccgaca gcacaagtga ggggctggag gacgctgtcc acagccgtgg   1920

tgccagaccc cctgcagcag gcccaggtgg ggatgaggac gaggacgagg aggacacggc   1980

cccagagtcc gcactggaca catccctgga caagtccttc tccgaggatg cggtgaccga   2040

ctcctcgggg tcgggcacac tccccagggc ccggggccgg gcctcaaagg ggaccgggaa   2100

gcgaaggaag aagcgtccct ccaggagcca ggaagaggtt ccccctgatt ctgatgataa   2160

taaaacaaag aaactgtgtg tgatccagta aggcctcagg cccaggccca aggccaagtg   2220

agagagccca ggccacagga catgctgcca ttctgccaag agaggctctt ctgggggcca   2280

ggctgggact gggccccgga aaccaaaact ccgtgcctta cccagccggg gccctcctgg   2340

agccttcttg gggtgttgtg gctgggaacc cgacaggcac cagtgccctg ccaggcctgg   2400

tgccctcctg gaccgcctgc acgtgccagc ctcccacctg cttcctaaag gcaaccctgg   2460

cccacacccg catgcgcccg gtgcagcctg ccaagggcca gtcggggggt gctgcgtcct   2520

gccagtgtcc accacagctc tgcctgccct tcagcccagc aaggtttaat caaaatgcaa   2580

tgctttgcaa gtctttactg cttggaggtg gctgagttgg gggccctggg caggggtaag   2640

ctggcaggca gtgccatggc aggccagggt cccctcccat ggggtctggc ccccgttcca   2700

gcatgtccag cccctgaagt tggagtgggg ggcggtctgc ctttgctgcc actgccaggc   2760

ctctgccctg cagctgaaac ttggccatca catcaacaga aaacccctcc cagtgccagc   2820

tgcccagcgt gggcaggccc tggggacaat acaggtccac ctgaggggct gcagggtgac   2880

acccagcagc cgctgccccc tcactgccca cccagcgagg gcagcctacc cgagcctgcc   2940

ccctgccagg tgtgtgccct gaggctggcg gctggatgcg tggccaataa aaagcagacc   3000

tagcccgg                                                            3008


<210>  8681
<211>  379
<212>  PRT
<213>  Homo sapiens

<400>  8681

Met Glu Glu Val Ile Val Ala Gln Val Asp His Gly Leu Gly Ser Ala 
1               5                   10                  15


Trp Val Pro Ser His Arg Arg Val Asn Pro Pro Thr Leu Arg Met Lys 
            20                  25                  30


Lys Leu Asn Trp Gln Lys Leu Pro Ser Asn Val Ala Arg Glu His Asn 
        35                  40                  45


Ser Met Trp Ala Ser Leu Ser Ser Pro Asp Ala Glu Ala Val Glu Pro 
    50                  55                  60


Asp Phe Ser Ser Ile Glu Arg Leu Phe Ser Phe Pro Ala Ala Lys Pro 
65                  70                  75                  80


Lys Glu Pro Thr Met Val Ala Pro Arg Ala Arg Lys Glu Pro Lys Glu 
                85                  90                  95


Ile Thr Phe Leu Asp Ala Lys Lys Ser Leu Asn Leu Asn Ile Phe Leu 
            100                 105                 110


Lys Gln Phe Lys Cys Ser Asn Glu Glu Val Ala Ala Met Ile Arg Ala 
        115                 120                 125


Gly Asp Thr Thr Lys Phe Asp Val Glu Val Leu Lys Gln Leu Leu Lys 
    130                 135                 140


Leu Leu Pro Glu Lys His Glu Ile Glu Asn Leu Arg Ala Phe Thr Glu 
145                 150                 155                 160


Glu Arg Ala Lys Leu Ala Ser Ala Asp His Phe Tyr Leu Leu Leu Leu 
                165                 170                 175


Ala Ile Pro Cys Tyr Gln Leu Arg Ile Glu Cys Met Leu Leu Cys Glu 
            180                 185                 190


Gly Ala Ala Ala Val Leu Asp Met Val Arg Pro Lys Ala Gln Leu Val 
        195                 200                 205


Leu Ala Ala Cys Glu Ser Leu Leu Thr Ser Arg Gln Leu Pro Ile Phe 
    210                 215                 220


Cys Gln Leu Ile Leu Arg Ile Gly Asn Phe Leu Asn Tyr Gly Ser His 
225                 230                 235                 240


Thr Gly Asp Ala Asp Gly Phe Lys Ile Ser Thr Leu Leu Lys Leu Thr 
                245                 250                 255


Glu Thr Lys Ser Gln Gln Asn Arg Val Thr Leu Leu His His Val Leu 
            260                 265                 270


Glu Glu Ala Glu Lys Ser His Pro Asp Leu Leu Gln Leu Pro Arg Asp 
        275                 280                 285


Leu Glu Gln Pro Ser Gln Ala Ala Gly Ile Asn Leu Glu Ile Ile Arg 
    290                 295                 300


Ser Glu Ala Ser Ser Asn Leu Lys Lys Leu Leu Glu Thr Glu Arg Lys 
305                 310                 315                 320


Val Ser Ala Ser Val Ala Glu Val Gln Glu Gln Tyr Thr Glu Arg Leu 
                325                 330                 335


Gln Ala Thr Ser Arg Pro Ser Gly His Trp Met Ser Cys Leu Arg Pro 
            340                 345                 350


Ser Ser Arg Ser Asn Gly Ser Trp Pro Thr Thr Cys Val Arg Thr Pro 
        355                 360                 365


Ser Ser Cys Pro Trp Arg Thr Arg Ser Ala Pro 
    370                 375


<210>  8682
<211>  2951
<212>  DNA
<213>  Homo sapiens

<400>  8682
cactactgcc ctgcacctgc agcccccccg tggcgggagg catggaggag gtcatcgtgg     60

cccaggtgga ccatggcttg ggctcagcat gggtccccag ccatcggcgg gtgaacccac    120

ccacactgcg catgaagaag ctgaactggc agaagctgcc atccaacgtg gcacgtgagc    180

acaactctat gtgggcgtcc ctgagcagcc ccgacgccga ggctgtggag cccgacttct    240

ccagcatcga gcgactattc tccttccctg cagccaagcc caaggagccc accatggtgg    300

ccccccgggc caggaaggag cccaaggaga tcactttcct cgatgccaag aagagcctga    360

acctcaacat cttcctgaag caatttaagt gctccaacga ggaggtcgct gctatgatcc    420

gggctggaga taccaccaag tttgatgtgg aggttctcaa acaactcctt aagctccttc    480

ccgagaagca cgagattgaa aacctgcggg cattcacaga ggagcgagcc aagctggcca    540

gcgccgacca cttctacctc ctcctgctgg ccattccctg ctaccagctg cgaatcgagt    600

gcatgctgct gtgtgagggc gcggccgccg tgctggacat ggtgcggccc aaggcccagc    660

tggtgctggc tgcctgcgaa agcctgctca ccagccgcca gctgcccatc ttctgccagc    720

tgatcctgag aattgggaac ttcctcaact acggcagcca caccggtgac gccgacggct    780

tcaagatcag cacattgctg aagctcacgg agaccaagtc ccagcagaac cgcgtgacgc    840

tgctgcacca cgtgctggag gaagcggaaa agagccaccc cgacctcctg cagctgcccc    900

gggacctgga acagccctcg caagcagcag ggatcaacct ggagatcatc cgctcagagg    960

ccagctccaa cctgaagaag cttctggaga ccgagcggaa ggtgtctgcc tccgtggccg   1020

aggtccagga gcagtacacc gagcgcctcc aggcaacatc tcggccttcc gggcactgga   1080

tgagctgttt gaggccatcg agcagaagca acgggagctg gccgactacc tgtgtgagga   1140

cgcccagcag ctgtccctgg aggacacgtt cagcaccatg aaggctttcc gggacctttt   1200

cctccgcgcc ctgaaggaga acaaggaccg gaaggagcag gcggcgaagg cagagaggag   1260

gaagcagcag ctggcggagg aggaggcgcg gcggcctcgg ggagaggacg ggaagcctgt   1320

caggaagggg cccgggaagc aggaggaggt gtgtgtcatc gatgccctgc tggctgacat   1380

caggaagggc ttccagctgc ggaagacagc ccggggccgc ggggacaccg acgggggcag   1440

caaggcagcc tccatggatc ccccaagagc cacagagcct gtggccacca gtaaccctgc   1500

aggagatccc gtgggcagca cgcgctgtcc cgcctctgag cccggccttg atgctacaac   1560

agccagcgag tcccggggct gggaccttgt agacgccgtg acccccggcc ctcagcccac   1620

cctggagcag ttggaggagg gtggtccacg gcccctggag aggcgttctt cctggtatgt   1680

ggatgccagc gatgtcctaa ccactgagga tccccagtgc ccccagccct tggagggggc   1740

ctggccggtg actctgggag atgctcaggc cctgaagccc ctcaagttct ccagcaacca   1800

gccccctgca gccggaagtt caaggcaaga tgccaaggat cccacgtcct tgctgggcgt   1860

cctccaggcc gaggccgaca gcacaagtga ggggctggag gacgctgtcc acagccgtgg   1920

tgccagaccc cctgcagcag gcccaggtgg ggatgaggac gaggacgagg aggacacggc   1980

cccagagtcc gcactggaca catccctgga caagtccttc tccgaggatg cggtgaccga   2040

ctcctcgggg tcgggcacac tccccagggc ccggggccgg gcctcaaagg ggaccgggaa   2100

gcgaaggaag aagcgtccct ccaggagcca ggaaggcctc aggcccaggc ccaaggccaa   2160

gtgagagagc ccaggccaca ggacatgctg ccattctgcc aagagaggct cttctggggg   2220

ccaggctggg actgggcccc ggaaaccaaa actccgtgcc ttacccagcc ggggccctcc   2280

tggagccttc ttggggtgtt gtggctggga acccgacagg caccagtgcc ctgccaggcc   2340

tggtgccctc ctggaccgcc tgcacgtgcc agcctcccac ctgcttccta aaggcaaccc   2400

tggcccacac ccgcatgcgc ccggtgcagc ctgccaaggg ccagtcgggg ggtgctgcgt   2460

cctgccagtg tccaccacag ctctgcctgc ccttcagccc agcaaggttt aatcaaaatg   2520

caatgctttg caagtcttta ctgcttggag gtggctgagt tgggggccct gggcaggggt   2580

aagctggcag gcagtgccat ggcaggccag ggtcccctcc catggggtct ggcccccgtt   2640

ccagcatgtc cagcccctga agttggagtg gggggcggtc tgcctttgct gccactgcca   2700

ggcctctgcc ctgcagctga aacttggcca tcacatcaac agaaaacccc tcccagtgcc   2760

agctgcccag cgtgggcagg ccctggggac aatacaggtc cacctgaggg gctgcagggt   2820

gacacccagc agccgctgcc ccctcactgc ccacccagcg agggcagcct acccgagcct   2880

gccccctgcc aggtgtgtgc cctgaggctg gcggctggat gcgtggccaa taaaaagcag   2940

acctagcccg g                                                        2951


<210>  8683
<211>  379
<212>  PRT
<213>  Homo sapiens

<400>  8683

Met Glu Glu Val Ile Val Ala Gln Val Asp His Gly Leu Gly Ser Ala 
1               5                   10                  15


Trp Val Pro Ser His Arg Arg Val Asn Pro Pro Thr Leu Arg Met Lys 
            20                  25                  30


Lys Leu Asn Trp Gln Lys Leu Pro Ser Asn Val Ala Arg Glu His Asn 
        35                  40                  45


Ser Met Trp Ala Ser Leu Ser Ser Pro Asp Ala Glu Ala Val Glu Pro 
    50                  55                  60


Asp Phe Ser Ser Ile Glu Arg Leu Phe Ser Phe Pro Ala Ala Lys Pro 
65                  70                  75                  80


Lys Glu Pro Thr Met Val Ala Pro Arg Ala Arg Lys Glu Pro Lys Glu 
                85                  90                  95


Ile Thr Phe Leu Asp Ala Lys Lys Ser Leu Asn Leu Asn Ile Phe Leu 
            100                 105                 110


Lys Gln Phe Lys Cys Ser Asn Glu Glu Val Ala Ala Met Ile Arg Ala 
        115                 120                 125


Gly Asp Thr Thr Lys Phe Asp Val Glu Val Leu Lys Gln Leu Leu Lys 
    130                 135                 140


Leu Leu Pro Glu Lys His Glu Ile Glu Asn Leu Arg Ala Phe Thr Glu 
145                 150                 155                 160


Glu Arg Ala Lys Leu Ala Ser Ala Asp His Phe Tyr Leu Leu Leu Leu 
                165                 170                 175


Ala Ile Pro Cys Tyr Gln Leu Arg Ile Glu Cys Met Leu Leu Cys Glu 
            180                 185                 190


Gly Ala Ala Ala Val Leu Asp Met Val Arg Pro Lys Ala Gln Leu Val 
        195                 200                 205


Leu Ala Ala Cys Glu Ser Leu Leu Thr Ser Arg Gln Leu Pro Ile Phe 
    210                 215                 220


Cys Gln Leu Ile Leu Arg Ile Gly Asn Phe Leu Asn Tyr Gly Ser His 
225                 230                 235                 240


Thr Gly Asp Ala Asp Gly Phe Lys Ile Ser Thr Leu Leu Lys Leu Thr 
                245                 250                 255


Glu Thr Lys Ser Gln Gln Asn Arg Val Thr Leu Leu His His Val Leu 
            260                 265                 270


Glu Glu Ala Glu Lys Ser His Pro Asp Leu Leu Gln Leu Pro Arg Asp 
        275                 280                 285


Leu Glu Gln Pro Ser Gln Ala Ala Gly Ile Asn Leu Glu Ile Ile Arg 
    290                 295                 300


Ser Glu Ala Ser Ser Asn Leu Lys Lys Leu Leu Glu Thr Glu Arg Lys 
305                 310                 315                 320


Val Ser Ala Ser Val Ala Glu Val Gln Glu Gln Tyr Thr Glu Arg Leu 
                325                 330                 335


Gln Ala Thr Ser Arg Pro Ser Gly His Trp Met Ser Cys Leu Arg Pro 
            340                 345                 350


Ser Ser Arg Ser Asn Gly Ser Trp Pro Thr Thr Cys Val Arg Thr Pro 
        355                 360                 365


Ser Ser Cys Pro Trp Arg Thr Arg Ser Ala Pro 
    370                 375


<210>  8684
<211>  3002
<212>  DNA
<213>  Homo sapiens

<400>  8684
gggtgcctgc tgtacgctgg acctggacct actgggcccc aggcaggaca tcctttagac     60

cctctgggag gctccagccc ctgcctgctg gatcgccagg ccccggggct gcgagagcct    120

cactggccgt gtccccaccc gacagagcac aactctatgt gggcgtccct gagcagcccc    180

gacgccgagg ctgtggagcc cgacttctcc agcatcgagc gactattctc cttccctgca    240

gccaagccca aggagcccac catggtggcc ccccgggcca ggaaggagcc caaggaggtg    300

gggacgggga ggggactcag accggggccg cctgcctggc caccctccgg taccagcctg    360

ttgggtgggg ggttttctag atcactttcc tcgatgccaa gaagagcctg aacctcaaca    420

tcttcctgaa gcaatttaag tgctccaacg aggaggtcgc tgctatgatc cgggctggag    480

ataccaccaa gtttgatgtg gaggttctca aacaactcct taagctcctt cccgagaagc    540

acgagattga aaacctgcgg gcattcacag aggagcgagc caagctggcc agcgccgacc    600

acttctacct cctcctgctg gccattccct gctaccagct gcgaatcgag tgcatgctgc    660

tgtgtgaggg cgcggccgcc gtgctggaca tggtgcggcc caaggcccag ctggtgctgg    720

ctgcctgcga aagcctgctc accagccgcc agctgcccat cttctgccag ctgatcctga    780

gaattgggaa cttcctcaac tacggcagcc acaccggtga cgccgacggc ttcaagatca    840

gcacattgct gaagctcacg gagaccaagt cccagcagaa ccgcgtgacg ctgctgcacc    900

acgtgctgga ggaagcggaa aagagccacc ccgacctcct gcagctgccc cgggacctgg    960

aacagccctc gcaagcagca gggatcaacc tggagatcat ccgctcagag gccagctcca   1020

acctgaagaa gcttctggag accgagcgga aggtgtctgc ctccgtggcc gaggtccagg   1080

agcagtacac cgagcgcctc caggcaacat ctcggccttc cgggcactgg atgagctgtt   1140

tgaggccatc gagcagaagc aacgggagct ggccgactac ctgtgtgagg acgcccagca   1200

gctgtccctg gaggacacgt tcagcaccat gaaggctttc cgggaccttt tcctccgcgc   1260

cctgaaggag aacaaggacc ggaaggagca ggcggcgaag gcagagagga ggaagcagca   1320

gctggcggag gaggaggcgc ggcggcctcg gggagaggac gggaagcctg tcaggaaggg   1380

gcccgggaag caggaggagg tgtgtgtcat cgatgccctg ctggctgaca tcaggaaggg   1440

cttccagctg cggaagacag cccggggccg cggggacacc gacgggggca gcaaggcagc   1500

ctccatggat cccccaagag ccacagagcc tgtggccacc agtaaccctg caggagatcc   1560

cgtgggcagc acgcgctgtc ccgcctctga gcccggcctt gatgctacaa cagccagcga   1620

gtcccggggc tgggaccttg tagacgccgt gacccccggc cctcagccca ccctggagca   1680

gttggaggag ggtggtccac ggcccctgga gaggcgttct tcctggtatg tggatgccag   1740

cgatgtccta accactgagg atccccagtg cccccagccc ttggaggggg cctggccggt   1800

gactctggga gatgctcagg ccctgaagcc cctcaagttc tccagcaacc agccccctgc   1860

agccggaagt tcaaggcaag atgccaagga tcccacgtcc ttgctgggcg tcctccaggc   1920

cgaggccgac agcacaagtg aggggctgga ggacgctgtc cacagccgtg gtgccagacc   1980

ccctgcagca ggcccaggtg gggatgagga cgaggacgag gaggacacgg ccccagagtc   2040

cgcactggac acatccctgg acaagtcctt ctccgaggat gcggtgaccg actcctcggg   2100

gtcgggcaca ctccccaggg cccggggccg ggcctcaaag gggaccggga agcgaaggaa   2160

gaagcgtccc tccaggagcc aggaaggcct caggcccagg cccaaggcca agtgagagag   2220

cccaggccac aggacatgct gccattctgc caagagaggc tcttctgggg gccaggctgg   2280

gactgggccc cggaaaccaa aactccgtgc cttacccagc cggggccctc ctggagcctt   2340

cttggggtgt tgtggctggg aacccgacag gcaccagtgc cctgccaggc ctggtgccct   2400

cctggaccgc ctgcacgtgc cagcctccca cctgcttcct aaaggcaacc ctggcccaca   2460

cccgcatgcg cccggtgcag cctgccaagg gccagtcggg gggtgctgcg tcctgccagt   2520

gtccaccaca gctctgcctg cccttcagcc cagcaaggtt taatcaaaat gcaatgcttt   2580

gcaagtcttt actgcttgga ggtggctgag ttgggggccc tgggcagggg taagctggca   2640

ggcagtgcca tggcaggcca gggtcccctc ccatggggtc tggcccccgt tccagcatgt   2700

ccagcccctg aagttggagt ggggggcggt ctgcctttgc tgccactgcc aggcctctgc   2760

cctgcagctg aaacttggcc atcacatcaa cagaaaaccc ctcccagtgc cagctgccca   2820

gcgtgggcag gccctgggga caatacaggt ccacctgagg ggctgcaggg tgacacccag   2880

cagccgctgc cccctcactg cccacccagc gagggcagcc tacccgagcc tgccccctgc   2940

caggtgtgtg ccctgaggct ggcggctgga tgcgtggcca ataaaaagca gacctagccc   3000

gg                                                                  3002


<210>  8685
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  8685

Met Lys Ala Phe Arg Asp Leu Phe Leu Arg Ala Leu Lys Glu Asn Lys 
1               5                   10                  15


Asp Arg Lys Glu Gln Ala Ala Lys Ala Glu Arg Arg Lys Gln Gln Leu 
            20                  25                  30


Ala Glu Glu Glu Ala Arg Arg Pro Arg Gly Glu Asp Gly Lys Pro Val 
        35                  40                  45


Arg Lys Gly Pro Gly Lys Gln Glu Glu Val Cys Val Ile Asp Ala Leu 
    50                  55                  60


Leu Ala Asp Ile Arg Lys Gly Phe Gln Leu Arg Lys Thr Ala Arg Gly 
65                  70                  75                  80


Arg Gly Asp Thr Asp Gly Gly Ser Lys Ala Ala Ser Met Asp Pro Pro 
                85                  90                  95


Arg Ala Thr Glu Pro Val Ala Thr Ser Asn Pro Ala Gly Asp Pro Val 
            100                 105                 110


Gly Ser Thr Arg Cys Pro Ala Ser Glu Pro Gly Leu Asp Ala Thr Thr 
        115                 120                 125


Ala Ser Glu Ser Arg Gly Trp Asp Leu Val Asp Ala Val Thr Pro Gly 
    130                 135                 140


Pro Gln Pro Thr Leu Glu Gln Leu Glu Glu Gly Gly Pro Arg Pro Leu 
145                 150                 155                 160


Glu Arg Arg Ser Ser Trp Tyr Val Asp Ala Ser Asp Val Leu Thr Thr 
                165                 170                 175


Glu Asp Pro Gln Cys Pro Gln Pro Leu Glu Gly Ala Trp Pro Val Thr 
            180                 185                 190


Leu Gly Asp Ala Gln Ala Leu Lys Pro Leu Lys Phe Ser Ser Asn Gln 
        195                 200                 205


Pro Pro Ala Ala Gly Ser Ser Arg Gln Asp Ala Lys Asp Pro Thr Ser 
    210                 215                 220


Leu Leu Gly Val Leu Gln Ala Glu Ala Asp Ser Thr Ser Glu Gly Leu 
225                 230                 235                 240


Glu Asp Ala Val His Ser Arg Gly Ala Arg Pro Pro Ala Ala Gly Pro 
                245                 250                 255


Gly Gly Asp Glu Asp Glu Asp Glu Glu Asp Thr Ala Pro Glu Ser Ala 
            260                 265                 270


Leu Asp Thr Ser Leu Asp Lys Ser Phe Ser Glu Asp Ala Val Thr Asp 
        275                 280                 285


Ser Ser Gly Ser Gly Thr Leu Pro Arg Ala Arg Gly Arg Ala Ser Lys 
    290                 295                 300


Gly Thr Gly Lys Arg Arg Lys Lys Arg Pro Ser Arg Ser Gln Glu Gly 
305                 310                 315                 320


Leu Arg Pro Arg Pro Lys Ala Lys 
                325


<210>  8686
<211>  452
<212>  DNA
<213>  Homo sapiens

<400>  8686
cgctgtcccg cctctgagcc cggccttgat gctacaacag ccagcgagtc ccggggctgg     60

gaccttgtag acgccgtgac ccccggccct cagcccaccc tggagcagtt ggaggagggt    120

ggtccacggc ccctggagag gcgttcttcc tggtatgtgg atgccagcga tgtcctaacc    180

actgaggatc cccagtgccc ccagcccttg gagggggcct ggccggtgac tctgggagat    240

gctcaggccc tgaagcccct caactgccca gcgtgggcag gccctgggga caatacaggt    300

ccacctgagg ggctgcaggg tgacacccag cagccgctgc cccctcactg cccacccagc    360

gagggcagcc tacccgagcc tgccccctgc caggtgtgtg ccctgaggct ggcggctgga    420

tgcgtggcca ataaaaagca gacctagccc gg                                  452


<210>  8687
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  8687

Arg Cys Pro Ala Ser Glu Pro Gly Leu Asp Ala Thr Thr Ala Ser Glu 
1               5                   10                  15


Ser Arg Gly Trp Asp Leu Val Asp Ala Val Thr Pro Gly Pro Gln Pro 
            20                  25                  30


Thr Leu Glu Gln Leu Glu Glu Gly Gly Pro Arg Pro Leu Glu Arg Arg 
        35                  40                  45


Ser Ser Trp Tyr Val Asp Ala Ser Asp Val Leu Thr Thr Glu Asp Pro 
    50                  55                  60


Gln Cys Pro Gln Pro Leu Glu Gly Ala Trp Pro Val Thr Leu Gly Asp 
65                  70                  75                  80


Ala Gln Ala Leu Lys Pro Leu Asn Cys Pro Ala Trp Ala Gly Pro Gly 
                85                  90                  95


Asp Asn Thr Gly Pro Pro Glu Gly Leu Gln Gly Asp Thr Gln Gln Pro 
            100                 105                 110


Leu Pro Pro His Cys Pro Pro Ser Glu Gly Ser Leu Pro Glu Pro Ala 
        115                 120                 125


Pro Cys Gln Val Cys Ala Leu Arg Leu Ala Ala Gly Cys Val Ala Asn 
    130                 135                 140


Lys Lys Gln Thr 
145


<210>  8688
<211>  1108
<212>  DNA
<213>  Homo sapiens

<400>  8688
actgcagttc cagtaaccct gtggctttcc tgctctgtct gttggtggag ggctatcttc     60

actctaagtg tgtcaatggc gtggggcctt ctggggcatg tccccaggaa gtctgtgagg    120

agaccgggac agtcgcaagg gcagatgctg ccagggacaa gtacactgca acccccctcc    180

tgttggacag tgtcctccca ccccgaggcc atgggtgggt ctatggagaa gcagattacc    240

ccccgcacac cgagtcttct ggggggcgac cagccaaagg tcaatcagcc aggcctcagg    300

cccaggccca aggccaagtg agagagccca ggccacagga catgctgcca ttctgccaag    360

agaggctctt ctgggggcca ggctgggact gggccccgga aaccaaaact ccgtgcctta    420

cccagccggg gccctcctgg agccttcttg gggtgttgtg gctgggaacc cgacaggcac    480

cagtgccctg ccaggcctgg tgccctcctg gaccgcctgc acgtgccagc ctcccacctg    540

cttcctaaag gcaaccctgg cccacacccg catgcgcccg gtgcagcctg ccaagggcca    600

gtcggggggt gctgcgtcct gccagtgtcc accacagctc tgcctgccct tcagcccagc    660

aaggtttaat caaaatgcaa tgctttgcaa gtctttactg cttggaggtg gctgagttgg    720

gggccctggg caggggtaag ctggcaggca gtgccatggc aggccagggt cccctcccat    780

ggggtctggc ccccgttcca gcatgtccag cccctgaagt tggagtgggg ggcggtctgc    840

ctttgctgcc actgccaggc ctctgccctg cagctgaaac ttggccatca catcaacaga    900

aaacccctcc cagtgccagc tgcccagcgt gggcaggccc tggggacaat acaggtccac    960

ctgaggggct gcagggtgac acccagcagc cgctgccccc tcactgccca cccagcgagg   1020

gcagcctacc cgagcctgcc ccctgccagg tgtgtgccct gaggctggcg gctggatgcg   1080

tggccaataa aaagcagacc tagcccgg                                      1108


<210>  8689
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  8689

Met Ala Trp Gly Leu Leu Gly His Val Pro Arg Lys Ser Val Arg Arg 
1               5                   10                  15


Pro Gly Gln Ser Gln Gly Gln Met Leu Pro Gly Thr Ser Thr Leu Gln 
            20                  25                  30


Pro Pro Ser Cys Trp Thr Val Ser Ser His Pro Glu Ala Met Gly Gly 
        35                  40                  45


Ser Met Glu Lys Gln Ile Thr Pro Arg Thr Pro Ser Leu Leu Gly Gly 
    50                  55                  60


Asp Gln Pro Lys Val Asn Gln Pro Gly Leu Arg Pro Arg Pro Lys Ala 
65                  70                  75                  80


Lys 



<210>  8690
<211>  725
<212>  DNA
<213>  Homo sapiens

<400>  8690
cattccattt catggctgaa gcacattcca ttgcatgcag ggaccacatt ttgtttgtct     60

gctcttctgt ccatggacat ctgggttgct tccagtttgg ggcttctgtg aatcctgctg    120

ctgtggacat ttgcgtagtc ctcgtgtgga tgctgctgtg gacgtctgcg tcgtcctcgt    180

gtggatgctg ctgtggacgt ctgcgtcgtc ctcgtgtgga tgctgctgtg gacgtctgcg    240

tagtctcgtg tggatgctgc tgtggacgtc tgcgtcgtcc tcgtgtggat gctgctgtgg    300

acatctgcgt agtctcgtgt ggatgctgct gtgaacgtct gcgtagtctc gtgtggatgc    360

tgctgtggac gtctgcgtag tctcgtgtgg atgctgctgt gcacgtctgc gtcgtcctcg    420

tgtggatgct gctgtggacg tctgcgtcgt cctcgtgtgg atgctgctgt ggacgtctgc    480

gtcgtcctcg tgtggatgct gctgtggacg tctgccgtcg tctcgtgtgg atgctgctgt    540

ggacgtctgc gtcgtcctcg tgtggatgct gctgtggacg tctgcgtcgt ctcgtgtgga    600

tgctgctgtg gacgtctgcg tcgtcctcgt gtggatgctg ctgtggacgt ctgcgtcgtc    660

ctcgtgtgga tgctgctgtg gacgtctgcg tcgtcctcgt gtggatgctg ctgtggacgt    720

ctgcg                                                                725


<210>  8691
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  8691

Met Leu Leu Cys Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly 
1               5                   10                  15


Arg Leu Arg Arg Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val 
            20                  25                  30


Leu Val Trp Met Leu Leu Trp Thr Ser Ala Val Val Ser Cys Gly Cys 
        35                  40                  45


Cys Cys Gly Arg Leu Arg Arg Pro Arg Val Asp Ala Ala Val Asp Val 
    50                  55                  60


Cys Val Val Ser Cys Gly Cys Cys Cys Gly Arg Leu Arg Arg Pro Arg 
65                  70                  75                  80


Val Asp Ala Ala Val Asp Val Cys Val Val Leu Val Trp Met Leu Leu 
                85                  90                  95


Trp Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly Arg 
            100                 105                 110


<210>  8692
<211>  483
<212>  DNA
<213>  Homo sapiens

<400>  8692
ttctgtgaat cctgctgctg tggacatttg cgtagtcctc gtgtggatgc tgctgtggac     60

gtctgcgtcg tcctcgtgtg gatgctgctg tggacgtctg cgtcgtcctc gtgtggatgc    120

tgctgtggac gtctgcgtag tctcgtgtgg atgctgctgt ggacgtctgc gtcgtcctcg    180

tgtggatgct gctgtggaca tctgccgtcg tctcgtgtgg atgctgctgt ggacgtctgc    240

gtcgtctcgt gtggatgctg ctgtggacgt ctgcgtcgtc tcgtgtggat gctgctgtgg    300

acgtctgcgt cgtcctcgtg tggatgctgc tgtggacgtc tgcgtcgtct cgtgtggatg    360

ctgctgtgga cgtctgcgtc gtcctcgtgt ggatgctgct gtggacgtct gcgtcgtcct    420

cgtgtggatg ctgctgtgga cgtctgcgtc gtcctcgtgt ggatgctgct gtggacgtct    480

gcg                                                                  483


<210>  8693
<211>  144
<212>  PRT
<213>  Homo sapiens

<400>  8693

Met Leu Leu Trp Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly 
1               5                   10                  15


Arg Leu Arg Arg Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val 
            20                  25                  30


Ser Cys Gly Cys Cys Cys Gly Arg Leu Arg Arg Pro Arg Val Asp Ala 
        35                  40                  45


Ala Val Asp Ile Cys Arg Arg Leu Val Trp Met Leu Leu Trp Thr Ser 
    50                  55                  60


Ala Ser Ser Arg Val Asp Ala Ala Val Asp Val Cys Val Val Ser Cys 
65                  70                  75                  80


Gly Cys Cys Cys Gly Arg Leu Arg Arg Pro Arg Val Asp Ala Ala Val 
                85                  90                  95


Asp Val Cys Val Val Ser Cys Gly Cys Cys Cys Gly Arg Leu Arg Arg 
            100                 105                 110


Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val Leu Val Trp Met 
        115                 120                 125


Leu Leu Trp Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly Arg 
    130                 135                 140


<210>  8694
<211>  2106
<212>  DNA
<213>  Homo sapiens

<400>  8694
tcgtgtggat gctgctgtgg acgtctgcgt cgtcctcgtg tggatgctgc tgtggacatc     60

tgcgtagtct cgtgtggatg ctgctgtgaa cgtctgcgta gtctcgtgtg gatgctgctg    120

tggacgtctg cgtagtctcg tgtggatgct gctgtgcacg tctgcgtcgt cctcgtgtgg    180

atgctgctgt ggacgtctgc gtcgtcctcg tgtggatgct gctgtggacg tctgcgtcgt    240

cctcgtgtgg atgctgctgt ggacgtctgc gtcgtctcgt gtggatgctg ctgtggacgt    300

ctgcgtcgtc tcgtgtggat gctgctgtgg acgtctgcgt cgtctcgtgt ggatgctgct    360

gtggacgtct gcgtcgtcct cgtgtggatg ctgctgtgga cgtctgcgtc gtctcgtgtg    420

gatgctgctg tggacgtctg cgtcgtcctc gtgtggatgc tgctgtggac gtctgcgtcg    480

tcctcgtgtg gatgctgctg tggacgtctg cgtcgtcctc gtgtggatgc tgctgtggac    540

gtctgcgtcg tcctcctgtg gatgctgctg tggacgtctg cgtcgtcctc gtgtggatgc    600

tgctgtggac gtctgcgtag tctcgtgtgg atgctgctgt ggacgtctgc gtagtctcgt    660

gtggatgctg ctgtggacgt ctgcgtcgtc ctcgatgctg ctgtggacgt ctgcgtcgtc    720

ctcgtgtgga tgctgctatg gacgtctgcg tagtctcgtg tggatgctgc tgtggacgtc    780

tgcgtcgtcc tcgtgtggat gctgctgtgg acgtctgcgt agtctcgtgt ggatgctgct    840

gtggacgtct gcgtagtctc gtgtggatgc tgctgtggac gtctgcgtcg tcctcgtgtg    900

gatgctgctg tggacgtctg cgtagtctcg tgtggatgct gctgtggacg tctgcgtcgt    960

cctcgtgtgg atgctgctgt ggacgtctgt gtagtctcat gtggatgctg cgagttttcg   1020

ttgctctggg gtagattcgt agcggaggaa caactgggcg acacgctaag tttatgttta   1080

actttttaag taactgccta actgttttcc aaagcagctg caccattttt cattcccatc   1140

catgctattg tttttcagtt aaatagctcc actcctcccc ctccccaccc tccacagaac   1200

tgccagtaaa actggactat ggagtattgg gtggggtcac ctacaaggtc atctgcagca   1260

agtgagacca tcgcccctcc tgcctggaga ggtgggactg gggaccctgt gacaggagga   1320

gctgcccttc ctggagcctg gtttttcttt ttcctctgtg ctccatgaga agtcagttta   1380

gtgggctaca gccagcaaag gaaccaaaac caacaggagc tctgggggtg ccttgcatgg   1440

cgaggctccg tggctgcacg cgtgtatgca ggtggctgtg ggtgtctgtg tgtcctgggc   1500

cactgtgtgc gatggtccca ctgggaggtg tggcccccaa agagtggaac ccacaggtgg   1560

acacacccat gcaccctcgt tcttgcccaa ggtcacacat cgagacagca gggcccagat   1620

ggatggcccc aagctcggtg gctcccgtgc tgcccacacc tggggacagg cccactgtgg   1680

ggggtaaggg gtggaggtgt tctaattcgg gctgagccgt gtgactggca ggggccccag   1740

ctgttgggcc tgggcaggac tgtttttaga aaagccccaa ctccctgccc ctacccgggc   1800

ccgtggctat ttatagtccg ggcctggaga agtcagtgag tcactagcgt tcgcctctgc   1860

agggtcagtc caagccccct tagtgaggtg gtctagcatg tcccccagtc ccccaagcct   1920

ctatctgaca tctgctagcc cagagcccca ggggtcccca ggaagggctc agagctggtg   1980

gcccccccca ggccttggca gcacctcctt gtctgatggg actttgtggt tcctggtgga   2040

catttaacat tgtcggtttc tctcatctgg aaacaaacct ccatgacgct cttggtttct   2100

cctgtt                                                              2106


<210>  8695
<211>  236
<212>  PRT
<213>  Homo sapiens

<400>  8695

Met Leu Leu Cys Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly 
1               5                   10                  15


Arg Leu Arg Arg Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val 
            20                  25                  30


Leu Val Trp Met Leu Leu Trp Thr Ser Ala Ser Ser Arg Val Asp Ala 
        35                  40                  45


Ala Val Asp Val Cys Val Val Ser Cys Gly Cys Cys Cys Gly Arg Leu 
    50                  55                  60


Arg Arg Leu Val Trp Met Leu Leu Trp Thr Ser Ala Ser Ser Ser Cys 
65                  70                  75                  80


Gly Cys Cys Cys Gly Arg Leu Arg Arg Leu Val Trp Met Leu Leu Trp 
                85                  90                  95


Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly Arg Leu Arg Arg 
            100                 105                 110


Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val Leu Val Trp Met 
        115                 120                 125


Leu Leu Trp Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly Arg 
    130                 135                 140


Leu Arg Arg Pro Arg Val Asp Ala Ala Val Asp Val Cys Val Val Ser 
145                 150                 155                 160


Cys Gly Cys Cys Cys Gly Arg Leu Arg Ser Leu Val Trp Met Leu Leu 
                165                 170                 175


Trp Thr Ser Ala Ser Ser Ser Met Leu Leu Trp Thr Ser Ala Ser Ser 
            180                 185                 190


Ser Cys Gly Cys Cys Tyr Gly Arg Leu Arg Ser Leu Val Trp Met Leu 
        195                 200                 205


Leu Trp Thr Ser Ala Ser Ser Ser Cys Gly Cys Cys Cys Gly Arg Leu 
    210                 215                 220


Arg Ser Leu Val Trp Met Leu Leu Trp Thr Ser Ala 
225                 230                 235


<210>  8696
<211>  1789
<212>  DNA
<213>  Homo sapiens

<400>  8696
ccccggcccg gctccattta atggcgcgga cgccggcggc ggcgggctcc tggccgggcc     60

agcgcagcgg aagagccaag ccagcatgtc ggggacccga gcctccaacg accggccccc    120

cggcgcaggc ggcgtcaagc gggggcggct gcagcaggag gcggcggcga ccggctcccg    180

cgtgacggtg gtgctgggcg cgcagtgggg ggacgagggc aaaggcaagg tggtggacct    240

gctggccacg gacgccgaca tcatcagccg ctgccagggg ggcaacaacg ccggccacac    300

ggtggtggtg gatgggaaag agtacgactt ccacctgctg cccagcggca tcatcaacac    360

caaggccgtg tccttcattg gcaacggggt ggtcatccac ttgccaggct tgtttgagga    420

agcagagaag aatgaaaaga aaggcctgaa ggactgggag aagaggctca tcatctctga    480

cagagcccac cttgtgtttg attttcacca ggctgtcgac ggacttcagg aagtgcagcg    540

ccaggcacaa gaggggaaga atataggcac caccaagaag ggaatcggac caacctactc    600

ttccaaagct gcccggacag gcctccgcat ctgcgacctc ctgtcagatt ttgatgagtt    660

ttcctccaga ttcaagaacc tggcccacca gcaccagtcg atgttcccca ccctggaaat    720

agacattgaa ggccaactca aaaggctcaa gggctttgct gagcggatca gacccatggt    780

ccgagatggt gtttacttta tgtatgaggc actccacggc ccccccaaga agatcctggt    840

ggagggtgcc aacgccgccc tcctcgacat tgacttcggg acctacccct ttgtgacttc    900

atccaactgc accgtgggcg gtgtgtgcac gggcctgggc atccccccgc agaacatagg    960

tgacgtgtat ggcgtggtga aagcctatac cacacgtgtg ggcatcgggg ccttccccac   1020

cgagcagatc aacgagattg gaggcctgct gcagacccgc ggccacgagt ggggagtgac   1080

cacaggcagg aagaggcgct gcggctggct cgacctgatg attctaagat atgctcacat   1140

ggtcaacgga ttcactgcgc tggccctgac gaagctggac atcctggacg tactgggtga   1200

ggttaaagtc ggtgtctcat acaagctgaa cgggaaaagg attccctatt tcccagctaa   1260

ccaggagatg cttcagaagg tcgaagttga gtatgaaacg ctgcctgggt ggaaagcaga   1320

caccacaggc gccaggaggt gggaggacct gcccccacag gcccagaact acatccgctt   1380

tgtggagaat cacgtgggag tcgcagtcaa atgggttggt gttggcaagt caagagagtc   1440

gatgatccag ctgttttagt cacagactga gctgatccca acaggccctg gcagcgtctg   1500

gacttgtgta aacagcagca gtcacgttcc tcggccgcca caaccaacac caaagcagga   1560

aaaccatttt ctgtactttt atatttctgt tcaacctgtt ggtttctaca atgattttaa   1620

acattggaaa gccagccttg tgtatatttt taaaaattat attcaaaatg agccaaagtg   1680

ctcagagacc ttctatgaca cattagtgtc acatggttgc gtgtccagcc gaagcagtgt   1740

aataaacatc tccaatggcc actgaatggg agcagttgtt acatgtttg               1789


<210>  8697
<211>  457
<212>  PRT
<213>  Homo sapiens

<400>  8697

Met Ser Gly Thr Arg Ala Ser Asn Asp Arg Pro Pro Gly Ala Gly Gly 
1               5                   10                  15


Val Lys Arg Gly Arg Leu Gln Gln Glu Ala Ala Ala Thr Gly Ser Arg 
            20                  25                  30


Val Thr Val Val Leu Gly Ala Gln Trp Gly Asp Glu Gly Lys Gly Lys 
        35                  40                  45


Val Val Asp Leu Leu Ala Thr Asp Ala Asp Ile Ile Ser Arg Cys Gln 
    50                  55                  60


Gly Gly Asn Asn Ala Gly His Thr Val Val Val Asp Gly Lys Glu Tyr 
65                  70                  75                  80


Asp Phe His Leu Leu Pro Ser Gly Ile Ile Asn Thr Lys Ala Val Ser 
                85                  90                  95


Phe Ile Gly Asn Gly Val Val Ile His Leu Pro Gly Leu Phe Glu Glu 
            100                 105                 110


Ala Glu Lys Asn Glu Lys Lys Gly Leu Lys Asp Trp Glu Lys Arg Leu 
        115                 120                 125


Ile Ile Ser Asp Arg Ala His Leu Val Phe Asp Phe His Gln Ala Val 
    130                 135                 140


Asp Gly Leu Gln Glu Val Gln Arg Gln Ala Gln Glu Gly Lys Asn Ile 
145                 150                 155                 160


Gly Thr Thr Lys Lys Gly Ile Gly Pro Thr Tyr Ser Ser Lys Ala Ala 
                165                 170                 175


Arg Thr Gly Leu Arg Ile Cys Asp Leu Leu Ser Asp Phe Asp Glu Phe 
            180                 185                 190


Ser Ser Arg Phe Lys Asn Leu Ala His Gln His Gln Ser Met Phe Pro 
        195                 200                 205


Thr Leu Glu Ile Asp Ile Glu Gly Gln Leu Lys Arg Leu Lys Gly Phe 
    210                 215                 220


Ala Glu Arg Ile Arg Pro Met Val Arg Asp Gly Val Tyr Phe Met Tyr 
225                 230                 235                 240


Glu Ala Leu His Gly Pro Pro Lys Lys Ile Leu Val Glu Gly Ala Asn 
                245                 250                 255


Ala Ala Leu Leu Asp Ile Asp Phe Gly Thr Tyr Pro Phe Val Thr Ser 
            260                 265                 270


Ser Asn Cys Thr Val Gly Gly Val Cys Thr Gly Leu Gly Ile Pro Pro 
        275                 280                 285


Gln Asn Ile Gly Asp Val Tyr Gly Val Val Lys Ala Tyr Thr Thr Arg 
    290                 295                 300


Val Gly Ile Gly Ala Phe Pro Thr Glu Gln Ile Asn Glu Ile Gly Gly 
305                 310                 315                 320


Leu Leu Gln Thr Arg Gly His Glu Trp Gly Val Thr Thr Gly Arg Lys 
                325                 330                 335


Arg Arg Cys Gly Trp Leu Asp Leu Met Ile Leu Arg Tyr Ala His Met 
            340                 345                 350


Val Asn Gly Phe Thr Ala Leu Ala Leu Thr Lys Leu Asp Ile Leu Asp 
        355                 360                 365


Val Leu Gly Glu Val Lys Val Gly Val Ser Tyr Lys Leu Asn Gly Lys 
    370                 375                 380


Arg Ile Pro Tyr Phe Pro Ala Asn Gln Glu Met Leu Gln Lys Val Glu 
385                 390                 395                 400


Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys Ala Asp Thr Thr Gly Ala 
                405                 410                 415


Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala Gln Asn Tyr Ile Arg Phe 
            420                 425                 430


Val Glu Asn His Val Gly Val Ala Val Lys Trp Val Gly Val Gly Lys 
        435                 440                 445


Ser Arg Glu Ser Met Ile Gln Leu Phe 
    450                 455


<210>  8698
<211>  1839
<212>  DNA
<213>  Homo sapiens

<400>  8698
gtcggcatgg tggggaggag ctgtggggtg gcaacccaga ggcaaggagg tgggcagagg     60

cccacgaacc tggccctgac cctcagctcg tccccagctc acagcacagc cctcccctgg    120

ctgcctccaa ggagtctcca gttactgagt ggccactccg tgccagctca gcccacccct    180

caccttccca gtgcctgtgg aggcccaact agggtgacgc tgggagagga gagggcttgg    240

aggagccacg ggtcaaatgc aggaggccac acctgcctgc ccaggaggac tgcaggagcc    300

ggatccttaa cacctggagg ggagcggggg ggcaacaacg ccggccacac ggtggtggtg    360

gatgggaaag agtacgactt ccacctgctg cccagcggca tcatcaacac caaggccgtg    420

tccttcattg gcaacggggt ggtcatccac ttgccaggct tgtttgagga agcagagaag    480

aatgaaaaga aaggcctgaa ggactgggag aagaggctca tcatctctga cagagcccac    540

cttgtgtttg attttcacca ggctgtcgac ggacttcagg aagtgcagcg ccaggcacaa    600

gaggggaaga atataggcac caccaagaag ggaatcggac caacctactc ttccaaagct    660

gcccggacag gcctccgcat ctgcgacctc ctgtcagatt ttgatgagtt ttcctccaga    720

ttcaagaacc tggcccacca gcaccagtcg atgttcccca ccctggaaat agacattgaa    780

ggccaactca aaaggctcaa gggctttgct gagcggatca gacccatggt ccgagatggt    840

gtttacttta tgtatgaggc actccacggc ccccccaaga agatcctggt ggagggtgcc    900

aacgccgccc tcctcgacat tgacttcggg acctacccct ttgtgacttc atccaactgc    960

accgtgggcg gtgtgtgcac gggcctgggc atccccccgc agaacatagg tgacgtgtat   1020

ggcgtggtga aagcctatac cacacgtgtg ggcatcgggg ccttccccac cgagcagatc   1080

aacgagattg gaggcctgct gcagacccgc ggccacgagt ggggagtgac cacaggcagg   1140

aagaggcgct gcggctggct cgacctgatg attctaagat atgctcacat ggtcaacgga   1200

ttcactgcgc tggccctgac gaagctggac atcctggacg tactgggtga ggttaaagtc   1260

ggtgtctcat acaagctgaa cgggaaaagg attccctatt tcccagctaa ccaggagatg   1320

cttcagaagg tcgaagttga gtatgaaacg ctgcctgggt ggaaagcaga caccacaggc   1380

gccaggaggt gggaggacct gcccccacag gcccagaact acatccgctt tgtggagaat   1440

cacgtgggag tcgcagtcaa atgggttggt gttggcaagt caagagagtc gatgatccag   1500

ctgttttagt cacagactga gctgatccca acaggccctg gcagcgtctg gacttgtgta   1560

aacagcagca gtcacgttcc tcggccgcca caaccaacac caaagcagga aaaccatttt   1620

ctgtactttt atatttctgt tcaacctgtt ggtttctaca atgattttaa acattggaaa   1680

gccagccttg tgtatatttt taaaaattat attcaaaatg agccaaagtg ctcagagacc   1740

ttctatgaca cattagtgtc acatggttgc gtgtccagcc gaagcagtgt aataaacatc   1800

tccaatggcc actgaatggg agcagttgtt acatgtttg                          1839


<210>  8699
<211>  500
<212>  PRT
<213>  Homo sapiens

<400>  8699

Met Val Gly Arg Ser Cys Gly Val Ala Thr Gln Arg Gln Gly Gly Gly 
1               5                   10                  15


Gln Arg Pro Thr Asn Leu Ala Leu Thr Leu Ser Ser Ser Pro Ala His 
            20                  25                  30


Ser Thr Ala Leu Pro Trp Leu Pro Pro Arg Ser Leu Gln Leu Leu Ser 
        35                  40                  45


Gly His Ser Val Pro Ala Gln Pro Thr Pro His Leu Pro Ser Ala Cys 
    50                  55                  60


Gly Gly Pro Thr Arg Val Thr Leu Gly Glu Glu Arg Ala Trp Arg Ser 
65                  70                  75                  80


His Gly Ser Asn Ala Gly Gly His Thr Cys Leu Pro Arg Arg Thr Ala 
                85                  90                  95


Gly Ala Gly Ser Leu Thr Pro Gly Gly Glu Arg Gly Gly Asn Asn Ala 
            100                 105                 110


Gly His Thr Val Val Val Asp Gly Lys Glu Tyr Asp Phe His Leu Leu 
        115                 120                 125


Pro Ser Gly Ile Ile Asn Thr Lys Ala Val Ser Phe Ile Gly Asn Gly 
    130                 135                 140


Val Val Ile His Leu Pro Gly Leu Phe Glu Glu Ala Glu Lys Asn Glu 
145                 150                 155                 160


Lys Lys Gly Leu Lys Asp Trp Glu Lys Arg Leu Ile Ile Ser Asp Arg 
                165                 170                 175


Ala His Leu Val Phe Asp Phe His Gln Ala Val Asp Gly Leu Gln Glu 
            180                 185                 190


Val Gln Arg Gln Ala Gln Glu Gly Lys Asn Ile Gly Thr Thr Lys Lys 
        195                 200                 205


Gly Ile Gly Pro Thr Tyr Ser Ser Lys Ala Ala Arg Thr Gly Leu Arg 
    210                 215                 220


Ile Cys Asp Leu Leu Ser Asp Phe Asp Glu Phe Ser Ser Arg Phe Lys 
225                 230                 235                 240


Asn Leu Ala His Gln His Gln Ser Met Phe Pro Thr Leu Glu Ile Asp 
                245                 250                 255


Ile Glu Gly Gln Leu Lys Arg Leu Lys Gly Phe Ala Glu Arg Ile Arg 
            260                 265                 270


Pro Met Val Arg Asp Gly Val Tyr Phe Met Tyr Glu Ala Leu His Gly 
        275                 280                 285


Pro Pro Lys Lys Ile Leu Val Glu Gly Ala Asn Ala Ala Leu Leu Asp 
    290                 295                 300


Ile Asp Phe Gly Thr Tyr Pro Phe Val Thr Ser Ser Asn Cys Thr Val 
305                 310                 315                 320


Gly Gly Val Cys Thr Gly Leu Gly Ile Pro Pro Gln Asn Ile Gly Asp 
                325                 330                 335


Val Tyr Gly Val Val Lys Ala Tyr Thr Thr Arg Val Gly Ile Gly Ala 
            340                 345                 350


Phe Pro Thr Glu Gln Ile Asn Glu Ile Gly Gly Leu Leu Gln Thr Arg 
        355                 360                 365


Gly His Glu Trp Gly Val Thr Thr Gly Arg Lys Arg Arg Cys Gly Trp 
    370                 375                 380


Leu Asp Leu Met Ile Leu Arg Tyr Ala His Met Val Asn Gly Phe Thr 
385                 390                 395                 400


Ala Leu Ala Leu Thr Lys Leu Asp Ile Leu Asp Val Leu Gly Glu Val 
                405                 410                 415


Lys Val Gly Val Ser Tyr Lys Leu Asn Gly Lys Arg Ile Pro Tyr Phe 
            420                 425                 430


Pro Ala Asn Gln Glu Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr 
        435                 440                 445


Leu Pro Gly Trp Lys Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp 
    450                 455                 460


Leu Pro Pro Gln Ala Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val 
465                 470                 475                 480


Gly Val Ala Val Lys Trp Val Gly Val Gly Lys Ser Arg Glu Ser Met 
                485                 490                 495


Ile Gln Leu Phe 
            500


<210>  8700
<211>  2642
<212>  DNA
<213>  Homo sapiens

<400>  8700
attctaccag tctggacaaa cgtatgctgt gtatctgcca ctatagtatc gtacagaatt     60

ttttactgtc ctaaaacccc cgagctccac ccatttcatt catctctccc ccctcaaccc    120

tcggcagcca ctcaccttat gctgtctcct cagttttgcc ttttccagaa tctcagagtt    180

ggaattgtac agtatgtcgc cttttcggat tggcttcttt cactcagtaa catgcattta    240

actttcctct atgtcttttc atggcttgaa agctcatttc ttttcagtgt tgaataatac    300

tccactgtct ggatggacca cagttgattt ctccttttgt ttactgatgg gcctcttgac    360

tgctgccgag tttcggcgat tatgaataga gctgcacatc tacgcgcagg tttctgcagg    420

gacatcaatt tccagctcct taaataccga ggaatgtgtt ttgcatccat caccaccatc    480

cacctccaga actttcttat cttcacacac tgaaatgctg aaatatcaaa taactcccca    540

gtctccctct cccagcccct ggcgcctccc attctacttt ctatctctat gaatttcact    600

tttccaggga cttcatataa gcggaatcat cctgtttgtg tccgtttgta actgccttat    660

ttcactcagc ataatgtctt cgaggcctgt gtcagaattt ccttcctttt ttaaggctga    720

atactcttcc atcgtatggg tagaccgtgt tctgcttacc cattcatctg tcaatggaca    780

gctcttggct actctgaata atgctgctat gaacataggt gtgcccattt catgctgggt    840

tgttttttgt tgttgtttgt ttgcttgttt gttttttgag acggagtctc gctctgtcac    900

ccagagtgca gtggcaggat ctcagctcac tgcaacctcc gcctcccagg ttcaagcgat    960

tctcctgcct cagcctcccg agtagctgag attacaggca tgcgccacca tgccaagata   1020

attttttgta tttttactag agatggggtt tcaccatgtg ggccaggctg gtttcgaact   1080

cctgacctca agtgatcctc ctgcctcagc ctcccaaagt gctaggatta caggcatgag   1140

ccaccgcacc cacccatttc atgctgttct taatgtatgt tttccagtgt ctgggacaca   1200

actctgtctc tcatgcctct gtctctcatg caggcaacgg ggtggtcatc cacttgccag   1260

gcttgtttga ggaagcagag aagaatgaaa agaaaggcct gaaggactgg gagaagaggc   1320

tcatcatctc tgacagagcc caccttgtgt ttgattttca ccaggctgtc gacggacttc   1380

aggaagtgca gcgccaggca caagagggga agaatatagg caccaccaag aagggaatcg   1440

gaccaaccta ctcttccaaa gctgcccgga caggcctccg catctgcgac ctcctgtcag   1500

attttgatga gttttcctcc agattcaaga acctggccca ccagcaccag tcgatgttcc   1560

ccaccctgga aatagacatt gaaggccaac tcaaaaggct caagggcttt gctgagcgga   1620

tcagacccat ggtccgagat ggtgtttact ttatgtatga ggcactccac ggccccccca   1680

agaagatcct ggtggagggt gccaacgccg ccctcctcga cattgacttc gggacctacc   1740

cctttgtgac ttcatccaac tgcaccgtgg gcggtgtgtg cacgggcctg ggcatccccc   1800

cgcagaacat aggtgacgtg tatggcgtgg tgaaagccta taccacacgt gtgggcatcg   1860

gggccttccc caccgagcag atcaacgaga ttggaggcct gctgcagacc cgcggccacg   1920

agtggggagt gaccacaggc aggaagaggc gctgcggctg gctcgacctg atgattctaa   1980

gatatgctca catggtcaac ggattcactg cgctggccct gacgaagctg gacatcctgg   2040

acgtactggg tgaggttaaa gtcggtgtct catacaagct gaacgggaaa aggattccct   2100

atttcccagc taaccaggag atgcttcaga aggtcgaagt tgagtatgaa acgctgcctg   2160

ggtggaaagc agacaccaca ggcgccagga ggtgggagga cctgccccca caggcccaga   2220

actacatccg ctttgtggag aatcacgtgg gagtcgcagt caaatgggtt ggtgttggca   2280

agtcaagaga gtcgatgatc cagctgtttt agtcacagac tgagctgatc ccaacaggcc   2340

ctggcagcgt ctggacttgt gtaaacagca gcagtcacgt tcctcggccg ccacaaccaa   2400

caccaaagca ggaaaaccat tttctgtact tttatatttc tgttcaacct gttggtttct   2460

acaatgattt taaacattgg aaagccagcc ttgtgtatat ttttaaaaat tatattcaaa   2520

atgagccaaa gtgctcagag accttctatg acacattagt gtcacatggt tgcgtgtcca   2580

gccgaagcag tgtaataaac atctccaatg gccactgaat gggagcagtt gttacatgtt   2640

tg                                                                  2642


<210>  8701
<211>  383
<212>  PRT
<213>  Homo sapiens

<400>  8701

Met Leu Phe Leu Met Tyr Val Phe Gln Cys Leu Gly His Asn Ser Val 
1               5                   10                  15


Ser His Ala Ser Val Ser His Ala Gly Asn Gly Val Val Ile His Leu 
            20                  25                  30


Pro Gly Leu Phe Glu Glu Ala Glu Lys Asn Glu Lys Lys Gly Leu Lys 
        35                  40                  45


Asp Trp Glu Lys Arg Leu Ile Ile Ser Asp Arg Ala His Leu Val Phe 
    50                  55                  60


Asp Phe His Gln Ala Val Asp Gly Leu Gln Glu Val Gln Arg Gln Ala 
65                  70                  75                  80


Gln Glu Gly Lys Asn Ile Gly Thr Thr Lys Lys Gly Ile Gly Pro Thr 
                85                  90                  95


Tyr Ser Ser Lys Ala Ala Arg Thr Gly Leu Arg Ile Cys Asp Leu Leu 
            100                 105                 110


Ser Asp Phe Asp Glu Phe Ser Ser Arg Phe Lys Asn Leu Ala His Gln 
        115                 120                 125


His Gln Ser Met Phe Pro Thr Leu Glu Ile Asp Ile Glu Gly Gln Leu 
    130                 135                 140


Lys Arg Leu Lys Gly Phe Ala Glu Arg Ile Arg Pro Met Val Arg Asp 
145                 150                 155                 160


Gly Val Tyr Phe Met Tyr Glu Ala Leu His Gly Pro Pro Lys Lys Ile 
                165                 170                 175


Leu Val Glu Gly Ala Asn Ala Ala Leu Leu Asp Ile Asp Phe Gly Thr 
            180                 185                 190


Tyr Pro Phe Val Thr Ser Ser Asn Cys Thr Val Gly Gly Val Cys Thr 
        195                 200                 205


Gly Leu Gly Ile Pro Pro Gln Asn Ile Gly Asp Val Tyr Gly Val Val 
    210                 215                 220


Lys Ala Tyr Thr Thr Arg Val Gly Ile Gly Ala Phe Pro Thr Glu Gln 
225                 230                 235                 240


Ile Asn Glu Ile Gly Gly Leu Leu Gln Thr Arg Gly His Glu Trp Gly 
                245                 250                 255


Val Thr Thr Gly Arg Lys Arg Arg Cys Gly Trp Leu Asp Leu Met Ile 
            260                 265                 270


Leu Arg Tyr Ala His Met Val Asn Gly Phe Thr Ala Leu Ala Leu Thr 
        275                 280                 285


Lys Leu Asp Ile Leu Asp Val Leu Gly Glu Val Lys Val Gly Val Ser 
    290                 295                 300


Tyr Lys Leu Asn Gly Lys Arg Ile Pro Tyr Phe Pro Ala Asn Gln Glu 
305                 310                 315                 320


Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys 
                325                 330                 335


Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala 
            340                 345                 350


Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val Gly Val Ala Val Lys 
        355                 360                 365


Trp Val Gly Val Gly Lys Ser Arg Glu Ser Met Ile Gln Leu Phe 
    370                 375                 380


<210>  8702
<211>  2279
<212>  DNA
<213>  Homo sapiens

<400>  8702
atgaaactgt cccacctctg atcttcaggc attcgattct cacaaggagc atgtggccta     60

gatccctcgc atgcacagtt cacaataggg ttcaggctcc tgtgagaatt gaatgacagg    120

aggtggagct caggccgtaa tgctagcttg cccgccactc atctgctctg cagcccaatt    180

ccaaacaggc caccaaccag tactggtcca cagcccaggg actggggacc cctgctgtaa    240

gtaacagaag cgagaggtca aaagcaagcg gaagaaaccc cagcactgct gaccacttct    300

tgggtttgcc cggccccttg gctttccaca ggctggccct gacgaagctg gacatcctgg    360

acgtactggg tgaggttaaa gtcggtgtct catacaagct gaacgggaaa aggattccct    420

atttcccagg tatgtgaagt ggggcaaccg ttctgcctgt tgggccgttt catggtattg    480

gaatagatag gacctgtgac ttctcagaga ggggtgagtt cccacgttca caggacacag    540

ggcaagcagc ttgtctccag tgaccagcct ccatcatggc ttttgcctct cacgggtttc    600

tccccacagc gttccccagg aggcctggct gggcaggggt ggctgtaggc cccttccagt    660

gttttgggaa tggctcaggg ggacagacta ctcgcctggg accctggggg accttcagct    720

gccttgagga aaaggcccac ctgcagggag ccacgggagg cacacaggag ttagtggatg    780

cggtcggctc tggaagatgt aaagctctat gcggacgtac aggatgacta tttcatctga    840

gaaaatacgc tttgtggcga gatttttaag acctaaccgg gatccctgct ccatgcaccc    900

cttcttctgg aaagcatgaa ggaggtgcca ttttcctggg tttcacaggt ttcagtttcg    960

tgtgcgtctg gatgtgcccc ctcgacctcg gtccagggtc atgttctgac cctgttcccc   1020

acaatggctt cctcctcagc agccctgggc gagctgctcc tggctggtct ccactcagca   1080

gatctttgta ggccacacag ggccacttgg ctacaggagc catgtgtgtc cttgcaggcg   1140

gtgtccctga ccctcctgac ccttgacctt tgagaggctg cacttgtgag gactgcaagc   1200

tctcctcatg gtggtccagg gtcccagggg gacacgcaaa cactgcctgg ctccaaggct   1260

caaacacact tgcagcgaga acccgtattc cagcatcttc catctgtaag ggtggttgtc   1320

ttctaccagg agccacagag tcctgcacag ggccgggatc cctgccctct gggagttgat   1380

gctcttgggg tgggaggaca cagatgcttc aggatccctt agtgcttcag gattctagag   1440

tctcagaatt tccaagccaa ggcttggagt gcctcagctg atgtcacagt ggaggttcta   1500

gcagagtggg tagcacatat gtgtcatgtc cctctggtct ggaaggcgtg tagtgtctga   1560

gccccactgc tgtcccctgc ttaccaccca acactgagaa aatcaaactg ggccacgtgc   1620

ccacttgctg ccttccttgc agctgagtcc ctaggcaagg aggccctgga tgggggtggc   1680

cgtgtcacca aatatccgct tccctggtga taggaggtct gtgggcccca ctcatctcct   1740

gtgtgcttcc cccagctaac caggagatgc ttcagaaggt cgaagttgag tatgaaacgc   1800

tgcctgggtg gaaagcagac accacaggcg ccaggaggtg ggaggacctg cccccacagg   1860

cccagaacta catccgcttt gtggagaatc acgtgggagt cgcagtcaaa tgggttggtg   1920

ttggcaagtc aagagagtcg atgatccagc tgttttagtc acagactgag ctgatcccaa   1980

caggccctgg cagcgtctgg acttgtgtaa acagcagcag tcacgttcct cggccgccac   2040

aaccaacacc aaagcaggaa aaccattttc tgtactttta tatttctgtt caacctgttg   2100

gtttctacaa tgattttaaa cattggaaag ccagccttgt gtatattttt aaaaattata   2160

ttcaaaatga gccaaagtgc tcagagacct tctatgacac attagtgtca catggttgcg   2220

tgtccagccg aagcagtgta ataaacatct ccaatggcca ctgaatggga gcagttgtt    2279


<210>  8703
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8703

Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys 
1               5                   10                  15


Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala 
            20                  25                  30


Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val Gly Val Ala Val Lys 
        35                  40                  45


Trp Val Gly Val Gly Lys Ser Arg Glu Ser Met Ile Gln Leu Phe 
    50                  55                  60


<210>  8704
<211>  728
<212>  DNA
<213>  Homo sapiens

<400>  8704
ctgtaagtaa cagaagcgag aggtcaaaag caagcggaag aaaccccagc actgctgacc     60

acttcttggg tttgcccggc cccttggctt tccacaggct ggccctgacg aagctggaca    120

tcctggacgt actgggtgag gttaaagtcg gtgtctcata caagctgaac gggaaaagga    180

ttccctattt cccagctaac caggagatgc ttcagaaggt cgaagttgag tatgaaacgc    240

tgcctgggtg gaaagcagac accacaggcg ccaggaggtg ggaggacctg cccccacagg    300

cccagaacta catccgcttt gtggagaatc acgtgggagt cgcagtcaaa tgggttggtg    360

ttggcaagtc aagagagtcg atgatccagc tgttttagtc acagactgag ctgatcccaa    420

caggccctgg cagcgtctgg acttgtgtaa acagcagcag tcacgttcct cggccgccac    480

aaccaacacc aaagcaggaa aaccattttc tgtactttta tatttctgtt caacctgttg    540

gtttctacaa tgattttaaa cattggaaag ccagccttgt gtatattttt aaaaattata    600

ttcaaaatga gccaaagtgc tcagagacct tctatgacac attagtgtca catggttgcg    660

tgtccagccg aagcagtgta ataaacatct ccaatggcca ctgaatggga gcagttgtta    720

catgtttg                                                             728


<210>  8705
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8705

Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys 
1               5                   10                  15


Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala 
            20                  25                  30


Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val Gly Val Ala Val Lys 
        35                  40                  45


Trp Val Gly Val Gly Lys Ser Arg Glu Ser Met Ile Gln Leu Phe 
    50                  55                  60


<210>  8706
<211>  675
<212>  DNA
<213>  Homo sapiens

<400>  8706
gcacatatgt gtcatgtccc tctggtctgg aaggcgtgta gtgtctgagc cccactgctg     60

tcccctgctt accacccaac actgagaaaa tcaaactggg ccacgtgccc acttgctgcc    120

ttccttgcag ctgagtccct agctaaccag gagatgcttc agaaggtcga agttgagtat    180

gaaacgctgc ctgggtggaa agcagacacc acaggcgcca ggaggtggga ggacctgccc    240

ccacaggccc agaactacat ccgctttgtg gagaatcacg tgggagtcgc agtcaaatgg    300

gttggtgttg gcaagtcaag agagtcgatg atccagctgt tttagtcaca gactgagctg    360

atcccaacag gccctggcag cgtctggact tgtgtaaaca gcagcagtca cgttcctcgg    420

ccgccacaac caacaccaaa gcaggaaaac cattttctgt acttttatat ttctgttcaa    480

cctgttggtt tctacaatga ttttaaacat tggaaagcca gccttgtgta tatttttaaa    540

aattatattc aaaatgagcc aaagtgctca gagaccttct atgacacatt agtgtcacat    600

ggttgcgtgt ccagccgaag cagtgtaata aacatctcca atggccactg aatgggagca    660

gttgttacat gtttg                                                     675


<210>  8707
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8707

Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys 
1               5                   10                  15


Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala 
            20                  25                  30


Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val Gly Val Ala Val Lys 
        35                  40                  45


Trp Val Gly Val Gly Lys Ser Arg Glu Ser Met Ile Gln Leu Phe 
    50                  55                  60


<210>  8708
<211>  737
<212>  DNA
<213>  Homo sapiens

<400>  8708
cctgcttacc acccaacact gagaaaatca aactgggcca cgtgcccact tgctgccttc     60

cttgcagctg agtccctagg caaggaggcc ctggatgggg gtggccgtgt caccaaatat    120

ccgcttccct ggtgatagga ggtctgtggg ccccactcat ctcctgtgtg cttcccccag    180

ctaaccagga gatgcttcag aaggtcgaag ttgagtatga aacgctgcct gggtggaaag    240

cagacaccac aggcgccagg aggtgggagg acctgccccc acaggcccag aactacatcc    300

gctttgtgga gaatcacgtg ggagtcgcag tgtgtatcat aacagtcttt tctgctctct    360

cagtcaaatg ggttggtgtt ggcaagtcaa gagagtcgat gatccagctg ttttagtcac    420

agactgagct gatcccaaca ggccctggca gcgtctggac ttgtgtaaac agcagcagtc    480

acgttcctcg gccgccacaa ccaacaccaa agcaggaaaa ccattttctg tacttttata    540

tttctgttca acctgttggt ttctacaatg attttaaaca ttggaaagcc agccttgtgt    600

atatttttaa aaattatatt caaaatgagc caaagtgctc agagaccttc tatgacacat    660

tagtgtcaca tggttgcgtg tccagccgaa gcagtgtaat aaacatctcc aatggccact    720

gaatgggagc agttgtt                                                   737


<210>  8709
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  8709

Met Leu Gln Lys Val Glu Val Glu Tyr Glu Thr Leu Pro Gly Trp Lys 
1               5                   10                  15


Ala Asp Thr Thr Gly Ala Arg Arg Trp Glu Asp Leu Pro Pro Gln Ala 
            20                  25                  30


Gln Asn Tyr Ile Arg Phe Val Glu Asn His Val Gly Val Ala Val Cys 
        35                  40                  45


Ile Ile Thr Val Phe Ser Ala Leu Ser Val Lys Trp Val Gly Val Gly 
    50                  55                  60


Lys Ser Arg Glu Ser Met Ile Gln Leu Phe 
65                  70


<210>  8710
<211>  772
<212>  DNA
<213>  Homo sapiens

<400>  8710
tgtgacgtca cggcgtcgtt ggtaaggggc tggcggccgg ggagctgcgt agctcccggc     60

cccgcggcca tgcccaagcg gagctgcccc ttcgcggacg tggccccgct acagctcaag    120

gtccgcgtga gccagaggga gttgagccgc ggcgtgtgcg ccgagcgcta ctcgcaggag    180

gtcttcgaga agaccaagcg actcctgttc ctcggggccc aggcctacct ggaccacgtg    240

tgggatgaag gctgtgccgt cgttcacctg ccagagtccc caaagcctgg ccctacaggg    300

gccccgaggg ctgcacgtgg gcagatgctg attggaccag acggccgcct gatcaggagc    360

cttgggcagg cctccgaagc tgacccatct ggggtagcgt ccattgcctg ttcctcatgc    420

gtgcgagccg tggatgggaa ggcggtctgc ggtcagtgtg agcgagccct gtgcgggcag    480

tgtgtgcgca cctgctgggg ctgcggctcc gtggcctgta ccctgtgtgg cctcgtggac    540

tgcagtgaca tgtacgagaa agtgctgtgc accagctgtg ccatgttcga gacctgaggc    600

tggctcaagc cggctgcctt caccgggagc cacgccgtgc atggcagcct tccctggacg    660

agcgctcggt gttcacactg aactgtgggg tcgacgggag gggtgccttt tacatgttct    720

attttgtatc ctaatgacag aatgaataaa cctctttata tttgcacaag ag            772


<210>  8711
<211>  175
<212>  PRT
<213>  Homo sapiens

<400>  8711

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Asp Pro Ser Gly Val Ala Ser Ile 
            100                 105                 110


Ala Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly 
        115                 120                 125


Gln Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Cys Trp Gly 
    130                 135                 140


Cys Gly Ser Val Ala Cys Thr Leu Cys Gly Leu Val Asp Cys Ser Asp 
145                 150                 155                 160


Met Tyr Glu Lys Val Leu Cys Thr Ser Cys Ala Met Phe Glu Thr 
                165                 170                 175


<210>  8712
<211>  3328
<212>  DNA
<213>  Homo sapiens

<400>  8712
gtgacgtcac ggcgtcgttg gtaaggggct ggcggccggg gagctgcgta gctcccggcc     60

ccgcggccat gcccaagcgg agctgcccct tcgcggacgt ggccccgcta cagctcaagg    120

tccgcgtgag ccagagggag ttgagccgcg gcgtgtgcgc cgagcgctac tcgcaggagg    180

tcttcgagaa gaccaagcga ctcctgttcc tcggggccca ggcctacctg acggccgcct    240

gatcaggagc cttgggcagg cctccgaagc tgacccatct ggggtagcgt ccattgcctg    300

ttcctcatgc gtgcgagccg tggatgggaa ggcggtctgc ggtcagtgtg agcgagccct    360

gtgcgggcag tgtgtgcgca cctgctgggg ctgcggctcc gtggcctgta ccctgtgtgg    420

cctcgtggag taagtacttc agtccctgga gctgctgaga tcccatagcc ccagcaagcc    480

gtgatggggg acgggtgggt cacccatgtg ggcccagaac acacacgtgt ggcccctgat    540

gcagtgccat ctggcattgc ctaacgggac atggtggcaa tagatgcttg gcccaacttt    600

agtggttagt aatcctctct aagggaaagc tgaacctcac agatgacctg ctctgtatcc    660

ggctctagtc cctgtcttca gccacttcct gttctgatct ttgagcaccc ccacctcctc    720

ctcctctggt ctttgagccc cccctccccc cgtccgagga gcccctggtt ggtgacacag    780

gtgcacaccg cagcttcacc acagtcatgc gtgccgtttg gttgtagacc ctctcaggca    840

ggaagtggag tgtttgtgta gtctcccatt tgtgggtggg tttgctgcag ctggctggat    900

cccgtcctta ctcctaaggt ggggaggggc gttctcaccc taggggctac tcacctggtg    960

gatgggagtg gacagtgtgg agcctgtttg ccctgccccg tgagaaagat gacttcatcc   1020

agacacatgt ggaactggct ccatagaccc aaagcaagct tagtccaaac aatgtctgaa   1080

attgtccatc taaaatagaa accacatgtt acatctcgag tcctttctct cgagcctttc   1140

ttcagtcggg gcagaggccc agactcattg gagacggaga gccctgggca gggggggcag   1200

caccagggag aagcgccgcg tgccagtgat cggctcccat ggcttcagca tgggcaggag   1260

tggggtaacg caccccatcc aggttgggaa tcatctgcag ggctagctat gaatgtggga   1320

tactctgtct ttgcttttca cccgctgagt tcatcttctt tcctagaagt aaactgaaaa   1380

gggcagggtt ttctcattgt ctggtggccc tctcaccaaa gcagaagtga acatagccat   1440

gggcaggttc agcggagagg tgggtcccag agcgctgcgt ggctggcctc ccactcctgc   1500

cctgcacacc atccttgagg gactcccttg cgcccatttc ctcctggcct ctacctactt   1560

tctgctgctg cttcctccca tacccacaga gttcacgttg agctgagtgg gccactgtcc   1620

ccactgtgga cacactcttt tatcgcagct acagcacagg aggtgggctc tgccctcttt   1680

cacaaataaa tgacttgttc caggtcacaa gccagaagtg gcattcccag gccaggcagc   1740

ccagctggtg gcacccgcag tctcctaccc cctcccctgc catttcctac ttcaggacca   1800

ggcgtcgcag gagtggggga aaacagggat ctgtccacac ggctctggtt taacacagat   1860

gcagcccagc agcctttggc gtcctgctga tggcctgcac tggcccacgc ctggcccgtc   1920

ctctgcaggg ctctccagct ggctgccggt ggcggtgagg ggctgtcttc gcggctcacc   1980

cacaatacta ctggcaaact ctgcaaacca agtggcaagc agttctggct gccttgttga   2040

ctccacggcc ctgtcgtgtt tggggtagcc attgccagtc ccgtttcctc gcaacatctc   2100

tcttaatcac tttctccctg tgttttgccg ggttccctag cctttacctt tagagctttc   2160

tttttttttt ttttttgaga cggagtctcg ctctgtcacc caggctggag tgcagtggtg   2220

cgatcttggc tcactgcaac ttccacctcc tgtgttcaag caattttcct gtctcagcct   2280

cccaagtagc tggagttaca ggcgtgcgct agcacgccca gctaattttt gtattcttag   2340

tagagacaga gtttcaccat gttggccagg ctggtctcga actcctgacc tcaggtgatc   2400

ctccggcctc agcctcccaa agtgctgagg taagccacac catacgcgtg agccaccatg   2460

cccggcccta cccttagtct tgatatatca gaaaagcact gtttgatgtg cttcagtgta   2520

aaccattgtg gttcggtgaa ttctggcagg tcatctggag gtttctttgg agagcttcta   2580

tcctactgga aacccaggtt gggccccatg tggattgatc ggcagtggga atcagctagg   2640

gctgctgtaa ctgagttcgc agacccagtg gcatagacag caaagaggta ctgccacgtg   2700

gctttggaga ccagaagtct gagaggaagg tgctggcagg gctggttcct tctgaggctg   2760

caatggaaaa cctgtcctgg cctctctcct ggcatctgct ggttatcttt ggtgttccct   2820

gtagacagct gccccctccc tgtatcttca tgtcgtcttc cttctctgtg tccttctctt   2880

cacgtagtct ttttaggacg ctggtcgtgt tgccttaggg cccccatgtc agtgccgtca   2940

tctagactga tgatgcccgc agtgatcctg tctccagata aggtcatgtc ctgaggtgtt   3000

ctgggttagg actttgacgt ttgaatggtg gggggtggtg gacacaattc agcccctgac   3060

agcagctttt ctctcccctc cctgacgctg tcgcagctgc agtgacatgt acgagaaagt   3120

gctgtgcacc agctgtgcca tgttcgagac ctgaggctgg ctcaagccgg ctgccttcac   3180

cgggagccac gccgtgcatg gcagccttcc ctggacgagc gctcggtgtt cacactgaac   3240

tgtggggtcg acgggagggg tgccttttac atgttctatt ttgtatccta atgacagaat   3300

gaataaacct ctttatattt gcacaaga                                      3328


<210>  8713
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8713

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Thr Ala Ala 
    50                  55


<210>  8714
<211>  574
<212>  DNA
<213>  Homo sapiens

<400>  8714
gacgtcacgg cgtcgttggt aaggggctgg cggccgggga gctgcgtagc tcccggcccc     60

gcggccatgc ccaagcggag ctgccccttc gcggacgtgg ccccgctaca gctcaaggtc    120

cgcgtgagcc agagggagtt gagccgcggc gtgtgcgccg agcgctactc gcaggaggtc    180

ttcgagaaga ccaagcgact cctgttcctc ggggcccagg cctacctgga ccacgtgtgg    240

gatgaaggct gtgccgtcgt tcacctgcca gagtccccaa agcctggccc tacaggggcc    300

ccgagggctg cacgtgggca gatgctgatt ggaccagacg gccgcctgat caggagcctt    360

gggcaggcct ccgaagctga cccatctggg gtagcgtcca ttgcctgttc ctcatgcgtg    420

cgagccgtgg atgggaaggc ggtctgcggt cagtgtgagc gagccctgtg cgggcagtgt    480

gtgcgcacct gctggggctg cggctccgtg gcctgtaccc tgtgtggcct cgtggagggc    540

tactcacctg gtggatggga gtggacagtg tgga                                574


<210>  8715
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  8715

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Asp Pro Ser Gly Val Ala Ser Ile 
            100                 105                 110


Ala Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly 
        115                 120                 125


Gln Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Cys Trp Gly 
    130                 135                 140


Cys Gly Ser Val Ala Cys Thr Leu Cys Gly Leu Val Glu Gly Tyr Ser 
145                 150                 155                 160


Pro Gly Gly Trp Glu Trp Thr Val 
                165


<210>  8716
<211>  1162
<212>  DNA
<213>  Homo sapiens

<400>  8716
gacgtcacgg cgtcgttggt aaggggctgg cggccgggga gctgcgtagc tcccggcccc     60

gcggccatgc ccaagcggag ctgccccttc gcggacgtgg ccccgctaca gctcaaggtc    120

cgcgtgagcc agagggagtt gagccgcggc gtgtgcgccg agcgctactc gcaggaggtc    180

ttcgagaaga ccaagcgact cctgttcctc ggggcccagg cctacctgga ccacgtgtgg    240

gatgaaggct gtgccgtcgt tcacctgcca gagtccccaa agcctggccc tacaggggcc    300

ccgagggctg cacgtgggca gatgctgatt ggaccagacg gccgcctgat caggagcctt    360

gggcaggcct ccgaagctga cccatctggg gtagcgtcca ttgcctgttc ctcatgcgtg    420

cgagccgtgg atgggaaggc ggtctgcggt cagtgtgagc gagccctgtg cgggcagtgt    480

gtgcgcacct gctggggctg cggctccgtg gcctgtaccc tgtgtggcct cgtggagccg    540

gccttgtgct ggaaagagca tgatgtgggc atgtgagaaa caaactcacc catccacacc    600

cgaagaatgg actcagagac ctcagagacc ggagaacagc aaaaaactat ccctaagagg    660

ccaggtgtgg tggctcacac cttataatcc caacgttttg ggaggacaag gcaggaggat    720

cacttgaggc ccggagttca agaccggcct gaacaacata gcgagaccct atctctacca    780

taaaaaagac ccagaacatc ctcgccagcc tgtgctccct atggggcacc ccctccagtg    840

gaagtgaggg cagccacgca cccctgggaa tgccttagag aggggccaat tgccatcgcc    900

aggggcctga ctctgcaacc atccacacct acggggagtc catttgagag atgaggaagc    960

tgaagctcca ggcccctggc tcgtgctggt cacccaacca cccggaacct ggtcgccaac   1020

ccgctgtcag ttgctcggca gtggactcct ctcctggctc agggcgcggt tccggcaggc   1080

gtccaccagg tggcagcacc ggcacattct gcaggctgtt ccggctcaga gctcgatgta   1140

gtgctctggg gtaacctggg cc                                            1162


<210>  8717
<211>  169
<212>  PRT
<213>  Homo sapiens

<400>  8717

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Asp Pro Ser Gly Val Ala Ser Ile 
            100                 105                 110


Ala Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly 
        115                 120                 125


Gln Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Cys Trp Gly 
    130                 135                 140


Cys Gly Ser Val Ala Cys Thr Leu Cys Gly Leu Val Glu Pro Ala Leu 
145                 150                 155                 160


Cys Trp Lys Glu His Asp Val Gly Met 
                165


<210>  8718
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  8718
gtcgttggta aggggctggc ggccggggag ctgcgtagct cccggccccg cggccatgcc     60

caagcggagc tgccccttcg cggacgtggc cccgctacag ctcaaggtcc gcgtgagcca    120

gagggagttg agccgcggcg tgtgcgccga gcgctactcg caggaggtct tcgacccatc    180

tggggtagcg tccattgcct gttcctcatg cgtgcgagcc gtggatggga aggcggtctg    240

cggtcagtgt gagcgagccc tgtgcgggca gtgtgtgcgc acctgctggg gctgcggctc    300

cgtggcctgt accctgtgtg gcctcgtgga ctgcagtgac atgtacgaga aagtgctgtg    360

caccagctgt gccatgttcg agacctgagg ctggctcaag ccggctgcct tcaccgggag    420

ccacgccgtg catggcagcc ttccctggac gagcgctcgg tgttcacact gaactgtggg    480

gtcgacggga ggggtgcctt ttacatgttc tattttgtat cctaatgaca gaatgaataa    540

acctctttat atttgcacaa ga                                             562


<210>  8719
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  8719

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Asp Pro Ser Gly Val Ala Ser Ile Ala 
        35                  40                  45


Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly Gln 
    50                  55                  60


Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Cys Trp Gly Cys 
65                  70                  75                  80


Gly Ser Val Ala Cys Thr Leu Cys Gly Leu Val Asp Cys Ser Asp Met 
                85                  90                  95


Tyr Glu Lys Val Leu Cys Thr Ser Cys Ala Met Phe Glu Thr 
            100                 105                 110


<210>  8720
<211>  3356
<212>  DNA
<213>  Homo sapiens

<400>  8720
gtcgttggta aggggctggc ggccggggag ctgcgtagct cccggccccg cggccatgcc     60

caagcggagc tgccccttcg cggacgtggc cccgctacag ctcaaggtcc gcgtgagcca    120

gagggagttg agccgcggcg tgtgcgccga gcgctactcg caggaggtct tcgagaagac    180

caagcgactc ctgttcctcg gggcccaggc ctacctggac cacgtgtggg atgaaggctg    240

tgccgtcgtt cacctgccag agtccccaaa gcctggccct acaggggccc cgagggctgc    300

acgtgggcag atgctgattg gaccagacgg ccgcctgatc aggagccttg ggcaggcctc    360

cgaagctgac ccatctgggg tagcgtccat tgcctgttcc tcatgcgtgc gagccgtgga    420

tgggaaggcg gtctgcggtc agtgtgagcg agccctgtgc gggcagtgtg tgcgcacctc    480

tgctgagatc ccatagcccc agcaagccgt gatgggggac gggtgggtca cccatgtggg    540

cccagaacac acacgtgtgg cccctgatgc agtgccatct ggcattgcct aacgggacat    600

ggtggcaata gatgcttggc ccaactttag tggttagtaa tcctctctaa gggaaagctg    660

aacctcacag atgacctgct ctgtatccgg ctctagtccc tgtcttcagc cacttcctgt    720

tctgatcttt gagcaccccc acctcctcct cctctggtct ttgagccccc cctccccccg    780

tccgaggagc ccctggttgg tgacacaggt gcacaccgca gcttcaccac agtcatgcgt    840

gccgtttggt tgtagaccct ctcaggcagg aagtggagtg tttgtgtagt ctcccatttg    900

tgggtgggtt tgctgcagct ggctggatcc cgtccttact cctaaggtgg ggaggggcgt    960

tctcacccta ggggctactc acctggtgga tgggagtgga cagtgtggag cctgtttgcc   1020

ctgccccgtg agaaagatga cttcatccag acacatgtgg aactggctcc atagacccaa   1080

agcaagctta gtccaaacaa tgtctgaaat tgtccatcta aaatagaaac cacatgttac   1140

atctcgagtc ctttctctcg agcctttctt cagtcggggc agaggcccag actcattgga   1200

gacggagagc cctgggcagg gggggcagca ccagggagaa gcgccgcgtg ccagtgatcg   1260

gctcccatgg cttcagcatg ggcaggagtg gggtaacgca ccccatccag gttgggaatc   1320

atctgcaggg ctagctatga atgtgggata ctctgtcttt gcttttcacc cgctgagttc   1380

atcttctttc ctagaagtaa actgaaaagg gcagggtttt ctcattgtct ggtggccctc   1440

tcaccaaagc agaagtgaac atagccatgg gcaggttcag cggagaggtg ggtcccagag   1500

cgctgcgtgg ctggcctccc actcctgccc tgcacaccat ccttgaggga ctcccttgcg   1560

cccatttcct cctggcctct acctactttc tgctgctgct tcctcccata cccacagagt   1620

tcacgttgag ctgagtgggc cactgtcccc actgtggaca cactctttta tcgcagctac   1680

agcacaggag gtgggctctg ccctctttca caaataaatg acttgttcca ggtcacaagc   1740

cagaagtggc attcccaggc caggcagccc agctggtggc acccgcagtc tcctaccccc   1800

tcccctgcca tttcctactt caggaccagg cgtcgcagga gtgggggaaa acagggatct   1860

gtccacacgg ctctggttta acacagatgc agcccagcag cctttggcgt cctgctgatg   1920

gcctgcactg gcccacgcct ggcccgtcct ctgcagggct ctccagctgg ctgccggtgg   1980

cggtgagggg ctgtcttcgc ggctcaccca caatactact ggcaaactct gcaaaccaag   2040

tggcaagcag ttctggctgc cttgttgact ccacggccct gtcgtgtttg gggtagccat   2100

tgccagtccc gtttcctcgc aacatctctc ttaatcactt tctccctgtg ttttgccggg   2160

ttccctagcc tttaccttta gagctttctt tttttttttt ttttgagacg gagtctcgct   2220

ctgtcaccca ggctggagtg cagtggtgcg atcttggctc actgcaactt ccacctcctg   2280

tgttcaagca attttcctgt ctcagcctcc caagtagctg gagttacagg cgtgcgctag   2340

cacgcccagc taatttttgt attcttagta gagacagagt ttcaccatgt tggccaggct   2400

ggtctcgaac tcctgacctc aggtgatcct ccggcctcag cctcccaaag tgctgaggta   2460

agccacacca tacgcgtgag ccaccatgcc cggccctacc cttagtcttg atatatcaga   2520

aaagcactgt ttgatgtgct tcagtgtaaa ccattgtggt tcggtgaatt ctggcaggtc   2580

atctggaggt ttctttggag agcttctatc ctactggaaa cccaggttgg gccccatgtg   2640

gattgatcgg cagtgggaat cagctagggc tgctgtaact gagttcgcag acccagtggc   2700

atagacagca aagaggtact gccacgtggc tttggagacc agaagtctga gaggaaggtg   2760

ctggcagggc tggttccttc tgaggctgca atggaaaacc tgtcctggcc tctctcctgg   2820

catctgctgg ttatctttgg tgttccctgt agacagctgc cccctccctg tatcttcatg   2880

tcgtcttcct tctctgtgtc cttctcttca cgtagtcttt ttaggacgct ggtcgtgttg   2940

ccttagggcc cccatgtcag tgccgtcatc tagactgatg atgcccgcag tgatcctgtc   3000

tccagataag gtcatgtcct gaggtgttct gggttaggac tttgacgttt gaatggtggg   3060

gggtggtgga cacaattcag cccctgacag cagcttttct ctcccctccc tgacgctgtc   3120

gcagctgcag tgacatgtac gagaaagtgc tgtgcaccag ctgtgccatg ttcgagacct   3180

gaggctggct caagccggct gccttcaccg ggagccacgc cgtgcatggc agccttccct   3240

ggacgagcgc tcggtgttca cactgaactg tggggtcgac gggaggggtg ccttttacat   3300

gttctatttt gtatcctaat gacagaatga ataaacctct ttatatttgc acaaga       3356


<210>  8721
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  8721

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Asp Pro Ser Gly Val Ala Ser Ile 
            100                 105                 110


Ala Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly 
        115                 120                 125


Gln Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Ser Ala Glu 
    130                 135                 140


Ile Pro 
145


<210>  8722
<211>  3424
<212>  DNA
<213>  Homo sapiens

<400>  8722
gtcgttggta aggggctggc ggccggggag ctgcgtagct cccggccccg cggccatgcc     60

caagcggagc tgccccttcg cggacgtggc cccgctacag ctcaaggtcc gcgtgagcca    120

gagggagttg agccgcggcg tgtgcgccga gcgctactcg caggaggtct tcgagaagac    180

caagcgactc ctgttcctcg gggcccaggc ctacctggac cacgtgtggg atgaaggctg    240

tgccgtcgtt cacctgccag agtccccaaa gcctggccct acaggggccc cgagggctgc    300

acgtgggcag atgctgattg gaccagacgg ccgcctgatc aggagccttg ggcaggcctc    360

cgaagctgac ccatctgggg tagcgtccat tgcctgttcc tcatgcgtgc gagccgtgga    420

tgggaaggcg gtctgcggtc agtgtgagcg agccctgtgc gggcagtgtg tgcgcacctg    480

ctggggctgc ggctccgtgg cctgtaccct gtgtggcctc gtggagtaag tacttcagtc    540

cctggagctg ctgagatccc atagccccag caagccgtga tgggggacgg gtgggtcacc    600

catgtgggcc cagaacacac acgtgtggcc cctgatgcag tgccatctgg cattgcctaa    660

cgggacatgg tggcaataga tgcttggccc aactttagtg gttagtaatc ctctctaagg    720

gaaagctgaa cctcacagat gacctgctct gtatccggct ctagtccctg tcttcagcca    780

cttcctgttc tgatctttga gcacccccac ctcctcctcc tctggtcttt gagccccccc    840

tccccccgtc cgaggagccc ctggttggtg acacaggtgc acaccgcagc ttcaccacag    900

tcatgcgtgc cgtttggttg tagaccctct caggcaggaa gtggagtgtt tgtgtagtct    960

cccatttgtg ggtgggtttg ctgcagctgg ctggatcccg tccttactcc taaggtgggg   1020

aggggcgttc tcaccctagg ggctactcac ctggtggatg ggagtggaca gtgtggagcc   1080

tgtttgccct gccccgtgag aaagatgact tcatccagac acatgtggaa ctggctccat   1140

agacccaaag caagcttagt ccaaacaatg tctgaaattg tccatctaaa atagaaacca   1200

catgttacat ctcgagtcct ttctctcgag cctttcttca gtcggggcag aggcccagac   1260

tcattggaga cggagagccc tgggcagggg gggcagcacc agggagaagc gccgcgtgcc   1320

agtgatcggc tcccatggct tcagcatggg caggagtggg gtaacgcacc ccatccaggt   1380

tgggaatcat ctgcagggct agctatgaat gtgggatact ctgtctttgc ttttcacccg   1440

ctgagttcat cttctttcct agaagtaaac tgaaaagggc agggttttct cattgtctgg   1500

tggccctctc accaaagcag aagtgaacat agccatgggc aggttcagcg gagaggtggg   1560

tcccagagcg ctgcgtggct ggcctcccac tcctgccctg cacaccatcc ttgagggact   1620

cccttgcgcc catttcctcc tggcctctac ctactttctg ctgctgcttc ctcccatacc   1680

cacagagttc acgttgagct gagtgggcca ctgtccccac tgtggacaca ctcttttatc   1740

gcagctacag cacaggaggt gggctctgcc ctctttcaca aataaatgac ttgttccagg   1800

tcacaagcca gaagtggcat tcccaggcca ggcagcccag ctggtggcac ccgcagtctc   1860

ctaccccctc ccctgccatt tcctacttca ggaccaggcg tcgcaggagt gggggaaaac   1920

agggatctgt ccacacggct ctggtttaac acagatgcag cccagcagcc tttggcgtcc   1980

tgctgatggc ctgcactggc ccacgcctgg cccgtcctct gcagggctct ccagctggct   2040

gccggtggcg gtgaggggct gtcttcgcgg ctcacccaca atactactgg caaactctgc   2100

aaaccaagtg gcaagcagtt ctggctgcct tgttgactcc acggccctgt cgtgtttggg   2160

gtagccattg ccagtcccgt ttcctcgcaa catctctctt aatcactttc tccctgtgtt   2220

ttgccgggtt ccctagcctt tacctttaga gctttctttt tttttttttt ttgagacgga   2280

gtctcgctct gtcacccagg ctggagtgca gtggtgcgat cttggctcac tgcaacttcc   2340

acctcctgtg ttcaagcaat tttcctgtct cagcctccca agtagctgga gttacaggcg   2400

tgcgctagca cgcccagcta atttttgtat tcttagtaga gacagagttt caccatgttg   2460

gccaggctgg tctcgaactc ctgacctcag gtgatcctcc ggcctcagcc tcccaaagtg   2520

ctgaggtaag ccacaccata cgcgtgagcc accatgcccg gccctaccct tagtcttgat   2580

atatcagaaa agcactgttt gatgtgcttc agtgtaaacc attgtggttc ggtgaattct   2640

ggcaggtcat ctggaggttt ctttggagag cttctatcct actggaaacc caggttgggc   2700

cccatgtgga ttgatcggca gtgggaatca gctagggctg ctgtaactga gttcgcagac   2760

ccagtggcat agacagcaaa gaggtactgc cacgtggctt tggagaccag aagtctgaga   2820

ggaaggtgct ggcagggctg gttccttctg aggctgcaat ggaaaacctg tcctggcctc   2880

tctcctggca tctgctggtt atctttggtg ttccctgtag acagctgccc cctccctgta   2940

tcttcatgtc gtcttccttc tctgtgtcct tctcttcacg tagtcttttt aggacgctgg   3000

tcgtgttgcc ttagggcccc catgtcagtg ccgtcatcta gactgatgat gcccgcagtg   3060

atcctgtctc cagataaggt catgtcctga ggtgttctgg gttaggactt tgacgtttga   3120

atggtggggg gtggtggaca caattcagcc cctgacagca gcttttctct cccctccctg   3180

acgctgtcgc agctgcagtg acatgtacga gaaagtgctg tgcaccagct gtgccatgtt   3240

cgagacctga ggctggctca agccggctgc cttcaccggg agccacgccg tgcatggcag   3300

ccttccctgg acgagcgctc ggtgttcaca ctgaactgtg gggtcgacgg gaggggtgcc   3360

ttttacatgt tctattttgt atcctaatga cagaatgaat aaacctcttt atatttgcac   3420

aaga                                                                3424


<210>  8723
<211>  157
<212>  PRT
<213>  Homo sapiens

<400>  8723

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Asp Pro Ser Gly Val Ala Ser Ile 
            100                 105                 110


Ala Cys Ser Ser Cys Val Arg Ala Val Asp Gly Lys Ala Val Cys Gly 
        115                 120                 125


Gln Cys Glu Arg Ala Leu Cys Gly Gln Cys Val Arg Thr Cys Trp Gly 
    130                 135                 140


Cys Gly Ser Val Ala Cys Thr Leu Cys Gly Leu Val Glu 
145                 150                 155


<210>  8724
<211>  4203
<212>  DNA
<213>  Homo sapiens

<400>  8724
gtcgttggta aggggctggc ggccggggag ctgcgtagct cccggccccg cggccatgcc     60

caagcggagc tgccccttcg cggacgtggc cccgctacag ctcaaggtcc gcgtgagcca    120

gagggagttg agccgcggcg tgtgcgccga gcgctactcg caggaggtct tcgagaagac    180

caagcgactc ctgttcctcg gggcccaggc ctacctggac cacgtgtggg atgaaggctg    240

tgccgtcgtt cacctgccag agtccccaaa gcctggccct acaggggccc cgagggctgc    300

acgtgggcag atgctgattg gaccagacgg ccgcctgatc aggagccttg ggcaggcctc    360

cgaagctggt gagtggcacc agcagccctt tgtggctgtg gcactgaggg caggtggtgg    420

cacgagcatt tttcttgatt tgcaaggtca ggcttttcct ccctgggtaa gcaggactct    480

gacccagagc ttggccttct ggctcagaag gctcctgtta tcaggaggtc tcacattcaa    540

gactggaagt tgttaaacag cttctaagta ctgggccaaa aaagcagcag agactccccg    600

ggtatcccgt ctgctttccg cctgcagccc cctcagatag tcccacaagg ctggaaacat    660

gccagtccca tccctatgca gtgtggggtc tcagagcatc acctgtgttg ctggttagaa    720

atgcaatccc cgactctacc tcaagtctgg ttggtgtgtc taggaggagc ccaggcacct    780

ctttgttaac cagtaaggca gtgggccaca ctgagaccca gatgggacac atggagttct    840

gacaagcaac aggggaagaa tggtccttcc agcactagcc tccaggtagc agagggacct    900

ggtaagggaa agagcactga acttggagtc aactacaggc atatctcacc ttggatctct    960

gtagtaaaac gggggtcctg tgcactgtac caggctcacg ggttgtcaga aggatccagt   1020

gtaggtgggg atggggtagg caggtcagag ccctctgccc tcaggtatgc atggaggcag   1080

gtagcccggc agtcccggaa actccagtct ccttgcagcc tgacggcttg gcgtttcttc   1140

ctcacagacc catctggggt agcgtccatt gcctgttcct catgcgtgcg agccgtggat   1200

gggaaggcgg tctgcggtca gtgtgagcga gccctgtgcg ggcagtgtgt gcgcacctgc   1260

tggggctgcg gctccgtggc ctgtaccctg tgtggcctcg tggagtaagt acttcagtcc   1320

ctggagctgc tgagatccca tagccccagc aagccgtgat gggggacggg tgggtcaccc   1380

atgtgggccc agaacacaca cgtgtggccc ctgatgcagt gccatctggc attgcctaac   1440

gggacatggt ggcaatagat gcttggccca actttagtgg ttagtaatcc tctctaaggg   1500

aaagctgaac ctcacagatg acctgctctg tatccggctc tagtccctgt cttcagccac   1560

ttcctgttct gatctttgag cacccccacc tcctcctcct ctggtctttg agccccccct   1620

ccccccgtcc gaggagcccc tggttggtga cacaggtgca caccgcagct tcaccacagt   1680

catgcgtgcc gtttggttgt agaccctctc aggcaggaag tggagtgttt gtgtagtctc   1740

ccatttgtgg gtgggtttgc tgcagctggc tggatcccgt ccttactcct aaggtgggga   1800

ggggcgttct caccctaggg gctactcacc tggtggatgg gagtggacag tgtggagcct   1860

gtttgccctg ccccgtgaga aagatgactt catccagaca catgtggaac tggctccata   1920

gacccaaagc aagcttagtc caaacaatgt ctgaaattgt ccatctaaaa tagaaaccac   1980

atgttacatc tcgagtcctt tctctcgagc ctttcttcag tcggggcaga ggcccagact   2040

cattggagac ggagagccct gggcaggggg ggcagcacca gggagaagcg ccgcgtgcca   2100

gtgatcggct cccatggctt cagcatgggc aggagtgggg taacgcaccc catccaggtt   2160

gggaatcatc tgcagggcta gctatgaatg tgggatactc tgtctttgct tttcacccgc   2220

tgagttcatc ttctttccta gaagtaaact gaaaagggca gggttttctc attgtctggt   2280

ggccctctca ccaaagcaga agtgaacata gccatgggca ggttcagcgg agaggtgggt   2340

cccagagcgc tgcgtggctg gcctcccact cctgccctgc acaccatcct tgagggactc   2400

ccttgcgccc atttcctcct ggcctctacc tactttctgc tgctgcttcc tcccataccc   2460

acagagttca cgttgagctg agtgggccac tgtccccact gtggacacac tcttttatcg   2520

cagctacagc acaggaggtg ggctctgccc tctttcacaa ataaatgact tgttccaggt   2580

cacaagccag aagtggcatt cccaggccag gcagcccagc tggtggcacc cgcagtctcc   2640

taccccctcc cctgccattt cctacttcag gaccaggcgt cgcaggagtg ggggaaaaca   2700

gggatctgtc cacacggctc tggtttaaca cagatgcagc ccagcagcct ttggcgtcct   2760

gctgatggcc tgcactggcc cacgcctggc ccgtcctctg cagggctctc cagctggctg   2820

ccggtggcgg tgaggggctg tcttcgcggc tcacccacaa tactactggc aaactctgca   2880

aaccaagtgg caagcagttc tggctgcctt gttgactcca cggccctgtc gtgtttgggg   2940

tagccattgc cagtcccgtt tcctcgcaac atctctctta atcactttct ccctgtgttt   3000

tgccgggttc cctagccttt acctttagag ctttcttttt tttttttttt tgagacggag   3060

tctcgctctg tcacccaggc tggagtgcag tggtgcgatc ttggctcact gcaacttcca   3120

cctcctgtgt tcaagcaatt ttcctgtctc agcctcccaa gtagctggag ttacaggcgt   3180

gcgctagcac gcccagctaa tttttgtatt cttagtagag acagagtttc accatgttgg   3240

ccaggctggt ctcgaactcc tgacctcagg tgatcctccg gcctcagcct cccaaagtgc   3300

tgaggtaagc cacaccatac gcgtgagcca ccatgcccgg ccctaccctt agtcttgata   3360

tatcagaaaa gcactgtttg atgtgcttca gtgtaaacca ttgtggttcg gtgaattctg   3420

gcaggtcatc tggaggtttc tttggagagc ttctatccta ctggaaaccc aggttgggcc   3480

ccatgtggat tgatcggcag tgggaatcag ctagggctgc tgtaactgag ttcgcagacc   3540

cagtggcata gacagcaaag aggtactgcc acgtggcttt ggagaccaga agtctgagag   3600

gaaggtgctg gcagggctgg ttccttctga ggctgcaatg gaaaacctgt cctggcctct   3660

ctcctggcat ctgctggtta tctttggtgt tccctgtaga cagctgcccc ctccctgtat   3720

cttcatgtcg tcttccttct ctgtgtcctt ctcttcacgt agtcttttta ggacgctggt   3780

cgtgttgcct tagggccccc atgtcagtgc cgtcatctag actgatgatg cccgcagtga   3840

tcctgtctcc agataaggtc atgtcctgag gtgttctggg ttaggacttt gacgtttgaa   3900

tggtgggggg tggtggacac aattcagccc ctgacagcag cttttctctc ccctccctga   3960

cgctgtcgca gctgcagtga catgtacgag aaagtgctgt gcaccagctg tgccatgttc   4020

gagacctgag gctggctcaa gccggctgcc ttcaccggga gccacgccgt gcatggcagc   4080

cttccctgga cgagcgctcg gtgttcacac tgaactgtgg ggtcgacggg aggggtgcct   4140

tttacatgtt ctattttgta tcctaatgac agaatgaata aacctcttta tatttgcaca   4200

aga                                                                 4203


<210>  8725
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  8725

Met Pro Lys Arg Ser Cys Pro Phe Ala Asp Val Ala Pro Leu Gln Leu 
1               5                   10                  15


Lys Val Arg Val Ser Gln Arg Glu Leu Ser Arg Gly Val Cys Ala Glu 
            20                  25                  30


Arg Tyr Ser Gln Glu Val Phe Glu Lys Thr Lys Arg Leu Leu Phe Leu 
        35                  40                  45


Gly Ala Gln Ala Tyr Leu Asp His Val Trp Asp Glu Gly Cys Ala Val 
    50                  55                  60


Val His Leu Pro Glu Ser Pro Lys Pro Gly Pro Thr Gly Ala Pro Arg 
65                  70                  75                  80


Ala Ala Arg Gly Gln Met Leu Ile Gly Pro Asp Gly Arg Leu Ile Arg 
                85                  90                  95


Ser Leu Gly Gln Ala Ser Glu Ala Gly Glu Trp His Gln Gln Pro Phe 
            100                 105                 110


Val Ala Val Ala Leu Arg Ala Gly Gly Gly Thr Ser Ile Phe Leu Asp 
        115                 120                 125


Leu Gln Gly Gln Ala Phe Pro Pro Trp Val Ser Arg Thr Leu Thr Gln 
    130                 135                 140


Ser Leu Ala Phe Trp Leu Arg Arg Leu Leu Leu Ser Gly Gly Leu Thr 
145                 150                 155                 160


Phe Lys Thr Gly Ser Cys 
                165


<210>  8726
<211>  756
<212>  DNA
<213>  Homo sapiens

<400>  8726
cccctcctgt cccaagaggt attcatggag cgcgcggccc tgccaggcac ggcggctttc     60

tcgggagacc aaaggcaggc aagacagatg tgccccgtct cccgggagct ccccagccta    120

gttggggaga ccagcaggag gagtcgccac aggtggtcgg ggcaggcaca gagaagacca    180

agcgactcct gttcctcggg gcccaggcct acctggacca cgtgtgggat gaaggctgtg    240

ccgtcgttca cctgccagag tccccaaagc ctggccctac aggggccccg agggctgcac    300

gtgggcagat gctgattgga ccagacggcc gcctgatcag gagccttggg caggcctccg    360

aagctgaccc atctggggta gcgtccattg cctgttcctc atgcgtgcga gccgtggatg    420

ggaaggcggt ctgcggtcag tgtgagcgag ccctgtgcgg gcagtgtgtg cgcacctgct    480

ggggctgcgg ctccgtggcc tgtaccctgt gtggcctcgt ggactgcagt gacatgtacg    540

agaaagtgct gtgcaccagc tgtgccatgt tcgagacctg aggctggctc aagccggctg    600

ccttcaccgg gagccacgcc gtgcatggca gccttccctg gacgagcgct cggtgttcac    660

actgaactgt ggggtcgacg ggaggggtgc cttttacatg ttctattttg tatcctaatg    720

acagaatgaa taaacctctt tatatttgca caagag                              756


<210>  8727
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  8727

Met Gly Arg Arg Ser Ala Val Ser Val Ser Glu Pro Cys Ala Gly Ser 
1               5                   10                  15


Val Cys Ala Pro Ala Gly Ala Ala Ala Pro Trp Pro Val Pro Cys Val 
            20                  25                  30


Ala Ser Trp Thr Ala Val Thr Cys Thr Arg Lys Cys Cys Ala Pro Ala 
        35                  40                  45


Val Pro Cys Ser Arg Pro Glu Ala Gly Ser Ser Arg Leu Pro Ser Pro 
    50                  55                  60


Gly Ala Thr Pro Cys Met Ala Ala Phe Pro Gly Arg Ala Leu Gly Val 
65                  70                  75                  80


His Thr Glu Leu Trp Gly Arg Arg Glu Gly Cys Leu Leu His Val Leu 
                85                  90                  95


Phe Cys Ile Leu Met Thr Glu 
            100


<210>  8728
<211>  430
<212>  DNA
<213>  Homo sapiens

<400>  8728
cggccgcctg atcaggagcc ttgggcaggc ctccgaagct gacccatctg gggtagcgtc     60

cattgcctgt tcctcatgcg tgcgagccgt ggatgggaag gcggtctgcg gtcagtgtga    120

gcgagccctg tgcgggcagt gtgtgcgcac ctgctggggc tgcggctccg tggcctgtac    180

cctgtgtggc ctcgtggact gcagtgacat gtacgagaaa gtgctgtgca ccagctgtgc    240

catgttcgag acctgaggct ggctcaagcc ggctgccttc accgggagcc acgccgtgca    300

tggcagcctt ccctggacga gcgctcggtg ttcacactga actgtggggt cgacgggagg    360

ggtgcctttt acatgttcta ttttgtatcc taatgacaga atgaataaac ctctttatat    420

ttgcacaaga                                                           430


<210>  8729
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  8729

Met Gly Arg Arg Ser Ala Val Ser Val Ser Glu Pro Cys Ala Gly Ser 
1               5                   10                  15


Val Cys Ala Pro Ala Gly Ala Ala Ala Pro Trp Pro Val Pro Cys Val 
            20                  25                  30


Ala Ser Trp Thr Ala Val Thr Cys Thr Arg Lys Cys Cys Ala Pro Ala 
        35                  40                  45


Val Pro Cys Ser Arg Pro Glu Ala Gly Ser Ser Arg Leu Pro Ser Pro 
    50                  55                  60


Gly Ala Thr Pro Cys Met Ala Ala Phe Pro Gly Arg Ala Leu Gly Val 
65                  70                  75                  80


His Thr Glu Leu Trp Gly Arg Arg Glu Gly Cys Leu Leu His Val Leu 
                85                  90                  95


Phe Cys Ile Leu Met Thr Glu 
            100


<210>  8730
<211>  306
<212>  DNA
<213>  Homo sapiens

<400>  8730
gacccatctg gggtagcgtc cattgcctgt tcctcatgcg tgcgagccgt ggatgggaag     60

gcggtctgcg gtcagtgtga gcgagccctg tgcgggcagt gtgtgcgcac cagctgtgcc    120

atgttcgaga cctgaggctg gctcaagccg gctgccttca ccgggagcca cgccgtgcat    180

ggcagccttc cctggacgag cgctcggtgt tcacactgaa ctgtggggtc gacgggaggg    240

gtgcctttta catgttctat tttgtatcct aatgacagaa tgaataaacc tctttatatt    300

tgcaca                                                               306


<210>  8731
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  8731

Met Gly Arg Arg Ser Ala Val Ser Val Ser Glu Pro Cys Ala Gly Ser 
1               5                   10                  15


Val Cys Ala Pro Ala Val Pro Cys Ser Arg Pro Glu Ala Gly Ser Ser 
            20                  25                  30


Arg Leu Pro Ser Pro Gly Ala Thr Pro Cys Met Ala Ala Phe Pro Gly 
        35                  40                  45


Arg Ala Leu Gly Val His Thr Glu Leu Trp Gly Arg Arg Glu Gly Cys 
    50                  55                  60


Leu Leu His Val Leu Phe Cys Ile Leu Met Thr Glu 
65                  70                  75


<210>  8732
<211>  724
<212>  DNA
<213>  Homo sapiens

<400>  8732
aggagttcac ggcccagatg atcaccatca caccacctga ccaagatgac agcatggagt     60

gtgtggacag cgagcgcagg ccccacttcc cccagttctc ctactcggcc agcggcacgg    120

cctgaggcgg cggtggactg cgctgggcct cagttcaacc tggtggcacc agatgcaacc    180

tcactatggt atgctggcca gcaccctctc ctgggggtgg caggcacaca gcagcccccc    240

agcactaagg ccgtgtctct gaggacgtca tcggaggctg ggcccctggg atgggaccag    300

ggatggggga tgggccaggg tttacccagt gggacagagg agcaaggttt aaatttgtta    360

ttgtgtatta tgttgttcaa atgcattttg ggggttttta atctttgtga caggaaagcc    420

ctcccccttc cccttctgtg tcacagttct tggtgactgt cccaccggga gcctccccct    480

cagatgatct ctccacggta gcacttgacc ttttcgacgc ttaacctttc cgctgtcgcc    540

ccaggccctc cctgactccc tgtgggggtg gccatccctg ggcccctcca cgcctcctgg    600

ccagacgctg ccgctgccgc tgcaccacgg cgttttttta caacattcaa ctttagtatt    660

tttactatta taatataata tggaaccttc cctccaaatt cttcaataaa agttgctttt    720

caaa                                                                 724


<210>  8733
<211>  136
<212>  PRT
<213>  Homo sapiens

<400>  8733

Met Thr Ala Trp Ser Val Trp Thr Ala Ser Ala Gly Pro Thr Ser Pro 
1               5                   10                  15


Ser Ser Pro Thr Arg Pro Ala Ala Arg Pro Glu Ala Ala Val Asp Cys 
            20                  25                  30


Ala Gly Pro Gln Phe Asn Leu Val Ala Pro Asp Ala Thr Ser Leu Trp 
        35                  40                  45


Tyr Ala Gly Gln His Pro Leu Leu Gly Val Ala Gly Thr Gln Gln Pro 
    50                  55                  60


Pro Ser Thr Lys Ala Val Ser Leu Arg Thr Ser Ser Glu Ala Gly Pro 
65                  70                  75                  80


Leu Gly Trp Asp Gln Gly Trp Gly Met Gly Gln Gly Leu Pro Ser Gly 
                85                  90                  95


Thr Glu Glu Gln Gly Leu Asn Leu Leu Leu Cys Ile Met Leu Phe Lys 
            100                 105                 110


Cys Ile Leu Gly Val Phe Asn Leu Cys Asp Arg Lys Ala Leu Pro Leu 
        115                 120                 125


Pro Leu Leu Cys His Ser Ser Trp 
    130                 135


<210>  8734
<211>  2480
<212>  DNA
<213>  Homo sapiens

<400>  8734
tggtcctcat ttcctcctcc cctcggaggt gtgtcacact ctgagtttcc tcctcccctc     60

ggaggtgtgt cacactctga gtgccagcct tggggttccc ttccctgacg ctgtgcagtg    120

aaggctggct ggtggtggac caggggtgct gccccttggc ctccacgagt tcctcctgtt    180

tgacctcaat cccttctgcc gcaaggagag cccagcccta tttctggctg tgcagggaca    240

gggacagcac ctacttttct ggcacatggg ggagtccgcc ctggagggag gcagctcttt    300

ctgcatgagt cgccatcctg ggtgctcatc tttcagggac cctaggagcc ctggccatca    360

ccccagctga tggggtctgc cagctgggtt cggaagcctg cactctgaga tgctgggtgc    420

cctgtcacca ggtgtgcttc tgccccgttc ccagcctgcc cctcccctga atgcctgtcc    480

taggctgtgt gcagctggtc gggctgggca gccctgggac ccagctgggc acctgttctc    540

ccattaacac agggtgccct ggtcctggtc cccgttcctg ccttgaggcc tgccaccctc    600

ctgccctgcc ctccaagggt atggggggcc tgggcagtgc tcaacctctg cccagccttg    660

accagagacc ttgctaattg acaatggaca atgctggtgc ccagcccaga ctctggggtg    720

gggcagtgct tgagggggtc cttgactgtg ggacctgagg ggctctctgg cagctcctca    780

cgtgtgcaca tcaccttata gtcacccttc atcctgggtc attgagagtc ctgtctgcag    840

ccagatgcca gcaggctgtg gtcctgtagt ccctgagcca tggaggcagg gtgggctcat    900

cctgtgcacc ttgttccaca gtctccctct ttcccaattt acaagaagac caataagaaa    960

aataagaaaa caagaaagaa aaaggaaaaa taaagttatc acctcctggt agcagggagg   1020

gtctctcaga gctgggctgc actacctcct gtcgcctgct ggggctgctg tgagggcagc   1080

tttgcgtctc agctgttgag ggttgtctcc gtgctcctgc acccctcatg tccctccctc   1140

ccagagctgc ctctgtgggg ggctggtggc ttgctgctct ctgacatcag tcctgcctgg   1200

agaccccttg gagatccagg tgctttgaag gtcttgagca cacttgaggg tgtgctggga   1260

gtggggagcg aagctcatga ctgtcccgtc tgcccacctc tgcagctcag cccacccttc   1320

aagccccagg tcacgtcgga gactgacacc aggtattttg atgaggagtt cacggcccag   1380

atgatcacca tcacaccacc tgaccaagat gacagcatgg agtgtgtgga cagcgagcgc   1440

aggccccact tcccccagtt ctcctactcg gccagcggca cggcctgagg cggcggtgga   1500

ctgcgctgga cgatagcttg gagggatgga gaggcggcct cgtgccatga tctgtattta   1560

atggttttta tttctcgggt gcatttgaga gaagccacgc tgtcctctcg agcccagatg   1620

gaaagacgtt tttgtgctgt gggcagcacc ctcccccgca gcggggtagg gaagaaaact   1680

atcctgcggg ttttaattta tttcatccag tttgttctcc gggtgtggcc tcagccctca   1740

gaacaatccg attcacgtag ggaaatgtta aggacttctg cagctatgcg caatgtggca   1800

ttggggggcc gggcaggtcc tgcccatgtg tcccctcact ctgtcagcca gccgccctgg   1860

gctgtctgtc accagctatc tgtcatctct ctggggccct gggcctcagt tcaacctggt   1920

ggcaccagat gcaacctcac tatggtatgc tggccagcac cctctcctgg gggtggcagg   1980

cacacagcag ccccccagca ctaaggccgt gtctctgagg acgtcatcgg aggctgggcc   2040

cctgggatgg gaccagggat gggggatggg ccagggttta cccagtggga cagaggagca   2100

aggtttaaat ttgttattgt gtattatgtt gttcaaatgc attttggggg tttttaatct   2160

ttgtgacagg aaagccctcc cccttcccct tctgtgtcac agttcttggt gactgtccca   2220

ccgggagcct ccccctcaga tgatctctcc acggtagcac ttgacctttt cgacgcttaa   2280

cctttccgct gtcgccccag gccctccctg actccctgtg ggggtggcca tccctgggcc   2340

cctccacgcc tcctggccag acgctgccgc tgccgctgca ccacggcgtt tttttacaac   2400

attcaacttt agtattttta ctattataat ataatatgga accttccctc caaattcttc   2460

aataaaagtt gcttttcaaa                                               2480


<210>  8735
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  8735

Met Ile Thr Ile Thr Pro Pro Asp Gln Asp Asp Ser Met Glu Cys Val 
1               5                   10                  15


Asp Ser Glu Arg Arg Pro His Phe Pro Gln Phe Ser Tyr Ser Ala Ser 
            20                  25                  30


Gly Thr Ala 
        35


<210>  8736
<211>  3190
<212>  DNA
<213>  Homo sapiens

<400>  8736
atggaggaga tccgcttccc gcgcacgctt ggtcccgagg ccaagtcctt gctttcaggg     60

ctgctcaaga aggaccccaa gcagaggctt ggcgggggct ccgaggacgc caaggagatc    120

atgcagcatc gcttctttgc cggtatcgtg tggcagcacg tgtacgagaa gaaggtgcgg    180

ctgctccccg catattcacg cgcacgcatg ctccccacat atccacactc acgcatgcac    240

gtggcacgct cgccagattt cccacacact cgccctcacc tcaggagcct gctgcagtcc    300

tggtacaagg agggccttgc tgcaccaacc tcagcgcctg gtgctcagag gctctggcac    360

tgccgggttc caccaggaaa ctggcctggt cctcatttcc tcctcccctc ggaggtgtgt    420

cacactctga gtttcctcct cccctcggag gtgtgtcaca ctctgagtgc cagccttggg    480

gttcccttcc ctgacgctgt gcagtgaagg ctggctggtg gtggaccagg ggtgctgccc    540

cttggcctcc acgagttcct cctgtttgac ctcaatccct tctgccgcaa ggagagccca    600

gccctatttc tggctgtgca gggacaggga cagcacctac ttttctggca catgggggag    660

tccgccctgg agggaggcag ctctttctgc atgagtcgcc atcctgggtg ctcatctttc    720

agggacccta ggagccctgg ccatcacccc agctgatggg gtctgccagc tgggttcgga    780

agcctgcact ctgagatgct gggtgccctg tcaccaggtg tgcttctgcc ccgttcccag    840

cctgcccctc ccctgaatgc ctgtcctagg ctgtgtgcag ctggtcgggc tgggcagccc    900

tgggacccag ctgggcacct gttctcccat taacacaggg tgccctggtc ctggtccccg    960

ttcctgcctt gaggcctgcc accctcctgc cctgccctcc aagggtatgg ggggcctggg   1020

cagtgctcaa cctctgccca gccttgacca gagaccttgc taattgacaa tggacaatgc   1080

tggtgcccag cccagactct ggggtggggc agtgcttgag ggggtccttg actgtgggac   1140

ctgaggggct ctctggcagc tcctcacgtg tgcacatcac cttatagtca cccttcatcc   1200

tgggtcattg agagtcctgt ctgcagccag atgccagcag gctgtggtcc tgtagtccct   1260

gagccatgga ggcagggtgg gctcatcctg tgcaccttgt tccacagtct ccctctttcc   1320

caatttacaa gaagaccaat aagaaaaata agaaaacaag aaagaaaaag gaaaaataaa   1380

gttatcacct cctggtagca gggagggtct ctcagagctg ggctgcacta cctcctgtcg   1440

cctgctgggg ctgctgtgag ggcagctttg cgtctcagct gttgagggtt gtctccgtgc   1500

tcctgcaccc ctcatgtccc tccctcccag agctgcctct gtggggggct ggtggcttgc   1560

tgctctctga catcagtcct gcctggagac cccttggaga tccaggtgct ttgaaggtct   1620

tgagcacact tgagggtgtg ctgggagtgg ggagcgaagc tcatgactgt cccgtctgcc   1680

cacctctgca gctcagccca cccttcaagc cccaggtcac gtcggagact gacaccaggt   1740

attttgatga ggagttcacg gcccagatga tcaccatcac accacctgac caaggtgagg   1800

ggccactgcc tgcccccgcc cactcccttt tctctccaca ctcagagagg cctgcagtgt   1860

tcagcttttt tggcttcaga tgttttaaaa tctaaatatt taaaaaggtt ccttttggag   1920

agtgccaatg atcagggtgg gaggcagtgc tctgagggcc caggtccctg tgtcaatctg   1980

tggggccctg tctcagtttc ctggcagtat ggcagcgtgc tggccgtgct ttaagaggtt   2040

ggcttcctac tggagctgtg ggtgggtgga ggtggcaggg aggtggggca ccggggtctg   2100

agctgtctac acccacagat gacagcatgg agtgtgtgga cagcgagcgc aggccccact   2160

tcccccagtt ctcctactcg gccagcggca cggcctgagg cggcggtgga ctgcgctgga   2220

cgatagcttg gagggatgga gaggcggcct cgtgccatga tctgtattta atggttttta   2280

tttctcgggt gcatttgaga gaagccacgc tgtcctctcg agcccagatg gaaagacgtt   2340

tttgtgctgt gggcagcacc ctcccccgca gcggggtagg gaagaaaact atcctgcggg   2400

ttttaattta tttcatccag tttgttctcc gggtgtggcc tcagccctca gaacaatccg   2460

attcacgtag ggaaatgtta aggacttctg cagctatgcg caatgtggca ttggggggcc   2520

gggcaggtcc tgcccatgtg tcccctcact ctgtcagcca gccgccctgg gctgtctgtc   2580

accagctatc tgtcatctct ctggggccct gggcctcagt tcaacctggt ggcaccagat   2640

gcaacctcac tatggtatgc tggccagcac cctctcctgg gggtggcagg cacacagcag   2700

ccccccagca ctaaggccgt gtctctgagg acgtcatcgg aggctgggcc cctgggatgg   2760

gaccagggat gggggatggg ccagggttta cccagtggga cagaggagca aggtttaaat   2820

ttgttattgt gtattatgtt gttcaaatgc attttggggg tttttaatct ttgtgacagg   2880

aaagccctcc cccttcccct tctgtgtcac agttcttggt gactgtccca ccgggagcct   2940

ccccctcaga tgatctctcc acggtagcac ttgacctttt cgacgcttaa cctttccgct   3000

gtcgccccag gccctccctg actccctgtg ggggtggcca tccctgggcc cctccacgcc   3060

tcctggccag acgctgccgc tgccgctgca ccacggcgtt tttttacaac attcaacttt   3120

agtattttta ctattataat ataatatgga accttccctc caaattcttc aataaaagtt   3180

gcttttcaaa                                                          3190


<210>  8737
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  8737

Met Glu Glu Ile Arg Phe Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser 
1               5                   10                  15


Leu Leu Ser Gly Leu Leu Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly 
            20                  25                  30


Gly Ser Glu Asp Ala Lys Glu Ile Met Gln His Arg Phe Phe Ala Gly 
        35                  40                  45


Ile Val Trp Gln His Val Tyr Glu Lys Lys Val Arg Leu Leu Pro Ala 
    50                  55                  60


Tyr Ser Arg Ala Arg Met Leu Pro Thr Tyr Pro His Ser Arg Met His 
65                  70                  75                  80


Val Ala Arg Ser Pro Asp Phe Pro His Thr Arg Pro His Leu Arg Ser 
                85                  90                  95


Leu Leu Gln Ser Trp Tyr Lys Glu Gly Leu Ala Ala Pro Thr Ser Ala 
            100                 105                 110


Pro Gly Ala Gln Arg Leu Trp His Cys Arg Val Pro Pro Gly Asn Trp 
        115                 120                 125


Pro Gly Pro His Phe Leu Leu Pro Ser Glu Val Cys His Thr Leu Ser 
    130                 135                 140


Phe Leu Leu Pro Ser Glu Val Cys His Thr Leu Ser Ala Ser Leu Gly 
145                 150                 155                 160


Val Pro Phe Pro Asp Ala Val Gln 
                165


<210>  8738
<211>  1375
<212>  DNA
<213>  Homo sapiens

<400>  8738
atgagaagct ttttgagctc atcctcatgg aggagatccg cttcccgcgc acgcttggtc     60

ccgaggccaa gtccttgctt tcagggctgc tcaagaagga ccccaagcag aggcttggcg    120

ggggctccga ggacgccaag gagatcatgc agcatcgctt ctttgccggt atcgtgtggc    180

agcacgtgta cgagaagaag ctcagcccac ccttcaagcc ccaggtcacg tcggagactg    240

acaccaggta ttttgatgag gagttcacgg cccagatgat caccatcaca ccacctgacc    300

aagatgacag catggagtgt gtggacagcg agcgcaggcc ccacttcccc cagttctcct    360

actcggccag cggcacggcc tgaggcggcg gtggactgcg ctggacgata gcttggaggg    420

atggagaggc ggcctcgtgc catgatctgt atttaatggt ttttatttct cgggtgcatt    480

tgagagaagc cacgctgtcc tctcgagccc agatggaaag acgtttttgt gctgtgggca    540

gcaccctccc ccgcagcggg gtagggaaga aaactatcct gcgggtttta atttatttca    600

tccagtttgt tctccgggtg tggcctcagc cctcagaaca atccgattca cgtagggaaa    660

tgttaaggac ttctgcagct atgcgcaatg tggcattggg gggccgggca ggtcctgccc    720

atgtgtcccc tcactctgtc agccagccgc cctgggctgt ctgtcaccag ctatctgtca    780

tctctctggg gccctgggcc tcagttcaac ctggtggcac cagatgcaac ctcactatgg    840

tatgctggcc agcaccctct cctgggggtg gcaggcacac agcagccccc cagcactaag    900

gccgtgtctc tgaggacgtc atcggaggct gggcccctgg gatgggacca gggatggggg    960

atgggccagg gtttacccag tgggacagag gagcaaggtt taaatttgtt attgtgtatt   1020

atgttgttca aatgcatttt gggggttttt aatctttgtg acaggaaagc cctccccctt   1080

ccccttctgt gtcacagttc ttggtgactg tcccaccggg agcctccccc tcagatgatc   1140

tctccacggt agcacttgac cttttcgacg cttaaccttt ccgctgtcgc cccaggccct   1200

ccctgactcc ctgtgggggt ggccatccct gggcccctcc acgcctcctg gccagacgct   1260

gccgctgccg ctgcaccacg gcgttttttt acaacattca actttagtat ttttactatt   1320

ataatataat atggaacctt ccctccaaat tcttcaataa aagttgcttt tcaaa        1375


<210>  8739
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  8739

Met Glu Glu Ile Arg Phe Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser 
1               5                   10                  15


Leu Leu Ser Gly Leu Leu Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly 
            20                  25                  30


Gly Ser Glu Asp Ala Lys Glu Ile Met Gln His Arg Phe Phe Ala Gly 
        35                  40                  45


Ile Val Trp Gln His Val Tyr Glu Lys Lys Leu Ser Pro Pro Phe Lys 
    50                  55                  60


Pro Gln Val Thr Ser Glu Thr Asp Thr Arg Tyr Phe Asp Glu Glu Phe 
65                  70                  75                  80


Thr Ala Gln Met Ile Thr Ile Thr Pro Pro Asp Gln Asp Asp Ser Met 
                85                  90                  95


Glu Cys Val Asp Ser Glu Arg Arg Pro His Phe Pro Gln Phe Ser Tyr 
            100                 105                 110


Ser Ala Ser Gly Thr Ala 
        115


<210>  8740
<211>  2833
<212>  DNA
<213>  Homo sapiens

<400>  8740
ggctccagga ggccccagct ccccatgccc tgcagccctg cctgccaggc ttttgttgag     60

gcccgggctc tgtcctgcag aacctgttct ggggacttgg cccaggaggt atttactgtg    120

aagggggcca gggtccagcc acttggttag ttccaggtca ctgtgtttgg ggacgattct    180

cctgcagatg gggcctttgc tttaaaagca cagtcgcctg tggtggaagg cgggagggtg    240

ggtctcgcct gggagggtgt gtcctccctt tgcgaaggcc ctggtgctgg gagcactgtc    300

ccctgctgag gtcccaactc accctggagg acctgagccc aggccacctt gctcaccttt    360

caaacactcc ttggcacctc aggggctgcc ggggcccagc ctgatggtgg cgtggcatga    420

ggcagtgtgg tgtggggcag tgtggtgtgg ggcagcgtgg catgggggca gtgtgatgtg    480

ggggtgtatg gtgtggggca gtgtgatggg gtgtgtggtg tggggcagtg tggtatcggg    540

cggtgtggta tcaggcagcg tggtgtcggg cagtgtggtg tggggctacg ggcggtgtgg    600

tatcaggcga cgtggtatca agcagcgtgg tgtcgggcag cgtggtgcgg ggctgccgtc    660

ctgcctgtgg ggccgcagtt ccagctcccc ttccttgcag gccctgaagt actctttcca    720

gacccacgac cgcctctgct ttgtcatgga gtacgccaac gggggcgagg taggggctgg    780

ggctgcgggg gatggacttc gcggcctgtg ggccgcccat ggtggggccg gtccttcccg    840

gagcctcggc tactctccat ggcaccagac ggtgctccct gctgggtggg tggtgtgatg    900

cctgcccagg cagctgcctg ctgtggggtg acttgttcct gctgagttag ggcttctgag    960

actttccagg cccccgtgcc ctctggtggc tggtcccttc cctgtgcaat gccgagaccc   1020

ggtctgagaa accccagccc tgcaggccat gggggcagag gcccgagcca cggctgtgcc   1080

tcaggttgcg cctcccgcag ctgttcttcc acctgtcccg ggagcgtgtg ttctccgagg   1140

accgggcccg cttctatggc gctgagattg tgtcagccct ggactacctg cactcggaga   1200

agaacgtggt gtaccgggac ctcaagctgg agaacctcat gctggacaag gacgggcaca   1260

ttaagatcac agacttcggg ctgtgcaagg aggggatcaa ggacggtgcc accatgaaga   1320

ccttttgcgg cacacctgag tacctggccc ccgaggtgct ggaggacaat gactacggcc   1380

gtgcagtgga ctggtggggg ctgggcgtgg tcatgtacga gatgatgtgc ggtcgcctgc   1440

ccttctacaa ccaggaccat gagaagcttt ttgagctcat cctcatggag gagatccgct   1500

tcccgcgcac gcttggtccc gaggccaagt ccttgctttc agggctgctc aagaaggacc   1560

ccaagcagag gcttggcggg ggctccgagg acgccaagga gatcatgcag catcgcttct   1620

ttgccggtat cgtgtggcag cacgtgtacg agaagaagct cagcccaccc ttcaagcccc   1680

aggtcacgtc ggagactgac accaggtatt ttgatgagga gttcacggcc cagatgatca   1740

ccatcacacc acctgaccaa gatgacagca tggagtgtgt ggacagcgag cgcaggcccc   1800

acttccccca gttctcctac tcggccagcg gcacggcctg aggcggcggt ggactgcgct   1860

ggacgatagc ttggagggat ggagaggcgg cctcgtgcca tgatctgtat ttaatggttt   1920

ttatttctcg ggtgcatttg agagaagcca cgctgtcctc tcgagcccag atggaaagac   1980

gtttttgtgc tgtgggcagc accctccccc gcagcggggt agggaagaaa actatcctgc   2040

gggttttaat ttatttcatc cagtttgttc tccgggtgtg gcctcagccc tcagaacaat   2100

ccgattcacg tagggaaatg ttaaggactt ctgcagctat gcgcaatgtg gcattggggg   2160

gccgggcagg tcctgcccat gtgtcccctc actctgtcag ccagccgccc tgggctgtct   2220

gtcaccagct atctgtcatc tctctggggc cctgggcctc agttcaacct ggtggcacca   2280

gatgcaacct cactatggta tgctggccag caccctctcc tgggggtggc aggcacacag   2340

cagcccccca gcactaaggc cgtgtctctg aggacgtcat cggaggctgg gcccctggga   2400

tgggaccagg gatgggggat gggccagggt ttacccagtg ggacagagga gcaaggttta   2460

aatttgttat tgtgtattat gttgttcaaa tgcattttgg gggtttttaa tctttgtgac   2520

aggaaagccc tcccccttcc ccttctgtgt cacagttctt ggtgactgtc ccaccgggag   2580

cctccccctc agatgatctc tccacggtag cacttgacct tttcgacgct taacctttcc   2640

gctgtcgccc caggccctcc ctgactccct gtgggggtgg ccatccctgg gcccctccac   2700

gcctcctggc cagacgctgc cgctgccgct gcaccacggc gtttttttac aacattcaac   2760

tttagtattt ttactattat aatataatat ggaaccttcc ctccaaattc ttcaataaaa   2820

gttgcttttc aaa                                                      2833


<210>  8741
<211>  200
<212>  PRT
<213>  Homo sapiens

<400>  8741

Met Leu Asp Lys Asp Gly His Ile Lys Ile Thr Asp Phe Gly Leu Cys 
1               5                   10                  15


Lys Glu Gly Ile Lys Asp Gly Ala Thr Met Lys Thr Phe Cys Gly Thr 
            20                  25                  30


Pro Glu Tyr Leu Ala Pro Glu Val Leu Glu Asp Asn Asp Tyr Gly Arg 
        35                  40                  45


Ala Val Asp Trp Trp Gly Leu Gly Val Val Met Tyr Glu Met Met Cys 
    50                  55                  60


Gly Arg Leu Pro Phe Tyr Asn Gln Asp His Glu Lys Leu Phe Glu Leu 
65                  70                  75                  80


Ile Leu Met Glu Glu Ile Arg Phe Pro Arg Thr Leu Gly Pro Glu Ala 
                85                  90                  95


Lys Ser Leu Leu Ser Gly Leu Leu Lys Lys Asp Pro Lys Gln Arg Leu 
            100                 105                 110


Gly Gly Gly Ser Glu Asp Ala Lys Glu Ile Met Gln His Arg Phe Phe 
        115                 120                 125


Ala Gly Ile Val Trp Gln His Val Tyr Glu Lys Lys Leu Ser Pro Pro 
    130                 135                 140


Phe Lys Pro Gln Val Thr Ser Glu Thr Asp Thr Arg Tyr Phe Asp Glu 
145                 150                 155                 160


Glu Phe Thr Ala Gln Met Ile Thr Ile Thr Pro Pro Asp Gln Asp Asp 
                165                 170                 175


Ser Met Glu Cys Val Asp Ser Glu Arg Arg Pro His Phe Pro Gln Phe 
            180                 185                 190


Ser Tyr Ser Ala Ser Gly Thr Ala 
        195                 200


<210>  8742
<211>  3492
<212>  DNA
<213>  Homo sapiens

<400>  8742
atggataaag tgtgctcagg tgagggttgg ctggtgggcc gctgcagggc gggggcctgt     60

ccagtgctcc cccacttact tgctgcctcc cgactgctgt aattatgggt ctgtaaccac    120

cctggactgg gtgctcctca ctgacggact tgtctgaacc tctctttgtc tccagcgccc    180

agcactgggc ctggcaaaac ctgagacgcc cggtacatgt tggccaaatg aatgaaccag    240

attcagaccg gcaggggcgc tgtggtttag gaggggcctg gggtttctcc caggaggttt    300

ttgggcttgc gctggagggc tctggactcc cgtttgcgcc agtggcctgc atcctggtcc    360

tgtcttcctc atgtttgaat ttctttgctt tcctagtctg gggagcaggg aggagccctg    420

tgccctgtcc caggatccat gggtaggaac accatggaca gggagagcaa acggggccat    480

ctgtcaccag gggcttaggg aaggccgagc cagcctgggt caaagaagtc aaaggggctg    540

cctggaggag gcagcctgtc agctggtgca tcaggttagg gaggctggga aggccttttg    600

gggatggggg tgatttgtcc aacggctggg ggaggtggga atggggaggt gagcaaggca    660

gcagctctca gggcctggct gttgcgggtg gtggtggcag gggctggagg ctctaagcct    720

agaataagga gaggcccagg tccagggaac tgtgttcaat tacatggatt tgacacttgg    780

cagccctgag tgttttgggg agagggaagg caggcgggca gatgggggtc agagagctta    840

gagggatggc agcccacctg ggaaggcagg tgcgggtgga gcccccaggc acgtgcagtg    900

ggtctctggc tcacccaggg cgaggagctg cccttagcca ggcgtggcct cacattcagc    960

ttcctttgct tctcccagag gctgtggcca ggccagctgg gctcggggag cgccagcctg   1020

agaggagcgc gtgagcgtcg cgggagcctc gggcaccatg agcgacgtgg ctattgtgaa   1080

ggagggttgg ctgcacaaac gaggggagta catcaagacc tggcggccac gctacttcct   1140

cctcaagaat gatggcacct tcattggcta caaggagcgg ccgcaggatg tggaccaacg   1200

tgaggctccc ctcaacaact tctctgtggc gcagtgccag ctgatgaaga cggagcggcc   1260

ccggcccaac accttcatca tccgctgcct gcagtggacc actgtcatcg aacgcacctt   1320

ccatgtggag actcctgagg agcgggagga gtggacaacc gccatccaga ctgtggctga   1380

cggcctcaag aagcaggagg aggaggagat ggacttccgg tcgggctcac ccagtgacaa   1440

ctcaggggct gaagagatgg aggtgtccct ggccaagccc aagcaccgcg tgaccatgaa   1500

cgagtttgag tacctgaagc tgctgggcaa gggcactttc ggcaaggtga tcctggtgaa   1560

ggagaaggcc acaggccgct actacgccat gaagatcctc aagaaggaag tcatcgtggc   1620

caaggacgag gtggcccaca cactcaccga gaaccgcgtc ctgcagaact ccaggcaccc   1680

cttcctcaca gccctgaagt actctttcca gacccacgac cgcctctgct ttgtcatgga   1740

gtacgccaac gggggcgagc tgttcttcca cctgtcccgg gagcgtgtgt tctccgagga   1800

ccgggcccgc ttctatggcg ctgagattgt gtcagccctg gactacctgc actcggagaa   1860

gaacgtggtg taccgggacc tcaagctgga gaacctcatg ctggacaagg acgggcacat   1920

taagatcaca gacttcgggc tgtgcaagga ggggatcaag gacggtgcca ccatgaagac   1980

cttttgcggc acacctgagt acctggcccc cgaggtgctg gaggacaatg actacggccg   2040

tgcagtggac tggtgggggc tgggcgtggt catgtacgag atgatgtgcg gtcgcctgcc   2100

cttctacaac caggaccatg agaagctttt tgagctcatc ctcatggagg agatccgctt   2160

cccgcgcacg cttggtcccg aggccaagtc cttgctttca gggctgctca agaaggaccc   2220

caagcagagg cttggcgggg gctccgagga cgccaaggag atcatgcagc atcgcttctt   2280

tgccggtatc gtgtggcagc acgtgtacga gaagaagctc agcccaccct tcaagcccca   2340

ggtcacgtcg gagactgaca ccaggtattt tgatgaggag ttcacggccc agatgatcac   2400

catcacacca cctgaccaag atgacagcat ggagtgtgtg gacagcgagc gcaggcccca   2460

cttcccccag ttctcctact cggccagcgg cacggcctga ggcggcggtg gactgcgctg   2520

gacgatagct tggagggatg gagaggcggc ctcgtgccat gatctgtatt taatggtttt   2580

tatttctcgg gtgcatttga gagaagccac gctgtcctct cgagcccaga tggaaagacg   2640

tttttgtgct gtgggcagca ccctcccccg cagcggggta gggaagaaaa ctatcctgcg   2700

ggttttaatt tatttcatcc agtttgttct ccgggtgtgg cctcagccct cagaacaatc   2760

cgattcacgt agggaaatgt taaggacttc tgcagctatg cgcaatgtgg cattgggggg   2820

ccgggcaggt cctgcccatg tgtcccctca ctctgtcagc cagccgccct gggctgtctg   2880

tcaccagcta tctgtcatct ctctggggcc ctgggcctca gttcaacctg gtggcaccag   2940

atgcaacctc actatggtat gctggccagc accctctcct gggggtggca ggcacacagc   3000

agccccccag cactaaggcc gtgtctctga ggacgtcatc ggaggctggg cccctgggat   3060

gggaccaggg atgggggatg ggccagggtt tacccagtgg gacagaggag caaggtttaa   3120

atttgttatt gtgtattatg ttgttcaaat gcattttggg ggtttttaat ctttgtgaca   3180

ggaaagccct cccccttccc cttctgtgtc acagttcttg gtgactgtcc caccgggagc   3240

ctccccctca gatgatctct ccacggtagc acttgacctt ttcgacgctt aacctttccg   3300

ctgtcgcccc aggccctccc tgactccctg tgggggtggc catccctggg cccctccacg   3360

cctcctggcc agacgctgcc gctgccgctg caccacggcg tttttttaca acattcaact   3420

ttagtatttt tactattata atataatatg gaaccttccc tccaaattct tcaataaaag   3480

ttgcttttca aa                                                       3492


<210>  8743
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  8743

Met Ser Asp Val Ala Ile Val Lys Glu Gly Trp Leu His Lys Arg Gly 
1               5                   10                  15


Glu Tyr Ile Lys Thr Trp Arg Pro Arg Tyr Phe Leu Leu Lys Asn Asp 
            20                  25                  30


Gly Thr Phe Ile Gly Tyr Lys Glu Arg Pro Gln Asp Val Asp Gln Arg 
        35                  40                  45


Glu Ala Pro Leu Asn Asn Phe Ser Val Ala Gln Cys Gln Leu Met Lys 
    50                  55                  60


Thr Glu Arg Pro Arg Pro Asn Thr Phe Ile Ile Arg Cys Leu Gln Trp 
65                  70                  75                  80


Thr Thr Val Ile Glu Arg Thr Phe His Val Glu Thr Pro Glu Glu Arg 
                85                  90                  95


Glu Glu Trp Thr Thr Ala Ile Gln Thr Val Ala Asp Gly Leu Lys Lys 
            100                 105                 110


Gln Glu Glu Glu Glu Met Asp Phe Arg Ser Gly Ser Pro Ser Asp Asn 
        115                 120                 125


Ser Gly Ala Glu Glu Met Glu Val Ser Leu Ala Lys Pro Lys His Arg 
    130                 135                 140


Val Thr Met Asn Glu Phe Glu Tyr Leu Lys Leu Leu Gly Lys Gly Thr 
145                 150                 155                 160


Phe Gly Lys Val Ile Leu Val Lys Glu Lys Ala Thr Gly Arg Tyr Tyr 
                165                 170                 175


Ala Met Lys Ile Leu Lys Lys Glu Val Ile Val Ala Lys Asp Glu Val 
            180                 185                 190


Ala His Thr Leu Thr Glu Asn Arg Val Leu Gln Asn Ser Arg His Pro 
        195                 200                 205


Phe Leu Thr Ala Leu Lys Tyr Ser Phe Gln Thr His Asp Arg Leu Cys 
    210                 215                 220


Phe Val Met Glu Tyr Ala Asn Gly Gly Glu Leu Phe Phe His Leu Ser 
225                 230                 235                 240


Arg Glu Arg Val Phe Ser Glu Asp Arg Ala Arg Phe Tyr Gly Ala Glu 
                245                 250                 255


Ile Val Ser Ala Leu Asp Tyr Leu His Ser Glu Lys Asn Val Val Tyr 
            260                 265                 270


Arg Asp Leu Lys Leu Glu Asn Leu Met Leu Asp Lys Asp Gly His Ile 
        275                 280                 285


Lys Ile Thr Asp Phe Gly Leu Cys Lys Glu Gly Ile Lys Asp Gly Ala 
    290                 295                 300


Thr Met Lys Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val 
305                 310                 315                 320


Leu Glu Asp Asn Asp Tyr Gly Arg Ala Val Asp Trp Trp Gly Leu Gly 
                325                 330                 335


Val Val Met Tyr Glu Met Met Cys Gly Arg Leu Pro Phe Tyr Asn Gln 
            340                 345                 350


Asp His Glu Lys Leu Phe Glu Leu Ile Leu Met Glu Glu Ile Arg Phe 
        355                 360                 365


Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser Leu Leu Ser Gly Leu Leu 
    370                 375                 380


Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly Gly Ser Glu Asp Ala Lys 
385                 390                 395                 400


Glu Ile Met Gln His Arg Phe Phe Ala Gly Ile Val Trp Gln His Val 
                405                 410                 415


Tyr Glu Lys Lys Leu Ser Pro Pro Phe Lys Pro Gln Val Thr Ser Glu 
            420                 425                 430


Thr Asp Thr Arg Tyr Phe Asp Glu Glu Phe Thr Ala Gln Met Ile Thr 
        435                 440                 445


Ile Thr Pro Pro Asp Gln Asp Asp Ser Met Glu Cys Val Asp Ser Glu 
    450                 455                 460


Arg Arg Pro His Phe Pro Gln Phe Ser Tyr Ser Ala Ser Gly Thr Ala 
465                 470                 475                 480


<210>  8744
<211>  4492
<212>  DNA
<213>  Homo sapiens

<400>  8744
gtgccccggg gttggagaaa gactcgccgc ggccggcctt caagtttgtg ggagggcccc     60

ggaaggagac ttcgtttccc acggacgaaa agttgtacgt ggtggcgggg tacccaggct    120

agccacaaag gactgtgacc ctcctgggcc ccggaactgc ttcctgtctt gggtgggccc    180

tggaggtcct gcccgcccat cccagaggcc aaggcttgga gggcagctgg ggcttgcccc    240

ttagattgag tatcctgggg cgctagcgag cttggtcctg tcgggacggc ctctgagtgc    300

tgccttggtc agcgggtgag cttgggcccc tgctctgcag ccagaggccg ccccacattc    360

actcctgggt ctctcggcct tgctccaggt ggccacttct tgactgcttt gagtccctca    420

tccgagcgaa gggcggacgg agtccgttgg tgggggtccg gttgcctctc ccgggagctg    480

tgtagacttc tcatacacca gggttctgga ggcagatgga ggagcccttt cgaaaacaga    540

gtattttttt ttaagttgtg acttaataat agtagcaaga atatgtgctt atggtaaagg    600

caggcggcag gtacggaggc tgtgggaagt cggggtccct ccgcccccac aggcagccct    660

gtgctggcct ggtgtatacg tttctgtgca gacgtacacc accctgtgtg agcacagatg    720

tatttttaca catggctctg gacagctgtc tgactctgtc agcagcaggc cttggagggg    780

ctcaggcccg tgtgggggtg gggggacatc cagaggtctt tgagtccagc cctctgcctc    840

caggccacgc ccactcagtg tcgtcagagc cccctgtgcc tgaggcgtgc gcggctcgga    900

gccctgccct cggagtcctg cggtgccttc ctcgagtctg gcctgctttc catcctgcta    960

agtacttggg gcatttccct ctttgggtaa ggtgtggtct tccctgtcct ggcattagac   1020

acaaggcagt gggccttcct gccattctaa gtgtagctta agacaatcag tgcaaagcaa   1080

ccctttgtgg gtgtccagcc cttgcctcgg gaggccagaa aggtggcctg gggggagagc   1140

gtctaagctg gctgtggaaa gacccatgtt gggatccatt ccacagaggt cgtcaggggt   1200

ctctgcctgg cctggaggtc ccagagagga ccctcctccc ctcaggaagg cccatctgga   1260

agggtagcag aggactgctc acaggaagag catgcgaagt gctctttctg gggatgcctg   1320

tagttggtga tgtgggaact gggttttgag ggatgcctag gagttcatcc atcagagggg   1380

aaatgaggaa gccatgcagg atcaatggat aaagtgtgct caggtgaggg ttggctggtg   1440

ggccgctgca gggcgggggc ctgtccagtg ctcccccact tacttgctgc ctcccgactg   1500

ctgtaattat gggtctgtaa ccaccctgga ctgggtgctc ctcactgacg gacttgtctg   1560

aacctctctt tgtctccagc gcccagcact gggcctggca aaacctgaga cgcccggtac   1620

atgttggcca aatgaatgaa ccagattcag accggcaggg gcgctgtggt ttaggagggg   1680

cctggggttt ctcccaggag gtttttgggc ttgcgctgga gggctctgga ctcccgtttg   1740

cgccagtggc ctgcatcctg gtcctgtctt cctcatgttt gaatttcttt gctttcctag   1800

tctggggagc agggaggagc cctgtgccct gtcccaggat ccatgggtag gaacaccatg   1860

gacagggaga gcaaacgggg ccatctgtca ccaggggctt agggaaggcc gagccagcct   1920

gggtcaaaga agtcaaaggg gctgcctgga ggaggcagcc tgtcagctgg tgcatcagag   1980

gctgtggcca ggccagctgg gctcggggag cgccagcctg agaggagcgc gtgagcgtcg   2040

cgggagcctc gggcaccatg agcgacgtgg ctattgtgaa ggagggttgg ctgcacaaac   2100

gaggggagta catcaagacc tggcggccac gctacttcct cctcaagaat gatggcacct   2160

tcattggcta caaggagcgg ccgcaggatg tggaccaacg tgaggctccc ctcaacaact   2220

tctctgtggc gcagtgccag ctgatgaaga cggagcggcc ccggcccaac accttcatca   2280

tccgctgcct gcagtggacc actgtcatcg aacgcacctt ccatgtggag actcctgagg   2340

agcgggagga gtggacaacc gccatccaga ctgtggctga cggcctcaag aagcaggagg   2400

aggaggagat ggacttccgg tcgggctcac ccagtgacaa ctcaggggct gaagagatgg   2460

aggtgtccct ggccaagccc aagcaccgcg tgaccatgaa cgagtttgag tacctgaagc   2520

tgctgggcaa gggcactttc ggcaaggtga tcctggtgaa ggagaaggcc acaggccgct   2580

actacgccat gaagatcctc aagaaggaag tcatcgtggc caaggacgag gtggcccaca   2640

cactcaccga gaaccgcgtc ctgcagaact ccaggcaccc cttcctcaca gccctgaagt   2700

actctttcca gacccacgac cgcctctgct ttgtcatgga gtacgccaac gggggcgagc   2760

tgttcttcca cctgtcccgg gagcgtgtgt tctccgagga ccgggcccgc ttctatggcg   2820

ctgagattgt gtcagccctg gactacctgc actcggagaa gaacgtggtg taccgggacc   2880

tcaagctgga gaacctcatg ctggacaagg acgggcacat taagatcaca gacttcgggc   2940

tgtgcaagga ggggatcaag gacggtgcca ccatgaagac cttttgcggc acacctgagt   3000

acctggcccc cgaggtgctg gaggacaatg actacggccg tgcagtggac tggtgggggc   3060

tgggcgtggt catgtacgag atgatgtgcg gtcgcctgcc cttctacaac caggaccatg   3120

agaagctttt tgagctcatc ctcatggagg agatccgctt cccgcgcacg cttggtcccg   3180

aggccaagtc cttgctttca gggctgctca agaaggaccc caagcagagg cttggcgggg   3240

gctccgagga cgccaaggag atcatgcagc atcgcttctt tgccggtatc gtgtggcagc   3300

acgtgtacga gaagaagctc agcccaccct tcaagcccca ggtcacgtcg gagactgaca   3360

ccaggtattt tgatgaggag ttcacggccc agatgatcac catcacacca cctgaccaag   3420

atgacagcat ggagtgtgtg gacagcgagc gcaggcccca cttcccccag ttctcctact   3480

cggccagcgg cacggcctga ggcggcggtg gactgcgctg gacgatagct tggagggatg   3540

gagaggcggc ctcgtgccat gatctgtatt taatggtttt tatttctcgg gtgcatttga   3600

gagaagccac gctgtcctct cgagcccaga tggaaagacg tttttgtgct gtgggcagca   3660

ccctcccccg cagcggggta gggaagaaaa ctatcctgcg ggttttaatt tatttcatcc   3720

agtttgttct ccgggtgtgg cctcagccct cagaacaatc cgattcacgt agggaaatgt   3780

taaggacttc tgcagctatg cgcaatgtgg cattgggggg ccgggcaggt cctgcccatg   3840

tgtcccctca ctctgtcagc cagccgccct gggctgtctg tcaccagcta tctgtcatct   3900

ctctggggcc ctgggcctca gttcaacctg gtggcaccag atgcaacctc actatggtat   3960

gctggccagc accctctcct gggggtggca ggcacacagc agccccccag cactaaggcc   4020

gtgtctctga ggacgtcatc ggaggctggg cccctgggat gggaccaggg atgggggatg   4080

ggccagggtt tacccagtgg gacagaggag caaggtttaa atttgttatt gtgtattatg   4140

ttgttcaaat gcattttggg ggtttttaat ctttgtgaca ggaaagccct cccccttccc   4200

cttctgtgtc acagttcttg gtgactgtcc caccgggagc ctccccctca gatgatctct   4260

ccacggtagc acttgacctt ttcgacgctt aacctttccg ctgtcgcccc aggccctccc   4320

tgactccctg tgggggtggc catccctggg cccctccacg cctcctggcc agacgctgcc   4380

gctgccgctg caccacggcg tttttttaca acattcaact ttagtatttt tactattata   4440

atataatatg gaaccttccc tccaaattct tcaataaaag ttgcttttca aa           4492


<210>  8745
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  8745

Met Ser Asp Val Ala Ile Val Lys Glu Gly Trp Leu His Lys Arg Gly 
1               5                   10                  15


Glu Tyr Ile Lys Thr Trp Arg Pro Arg Tyr Phe Leu Leu Lys Asn Asp 
            20                  25                  30


Gly Thr Phe Ile Gly Tyr Lys Glu Arg Pro Gln Asp Val Asp Gln Arg 
        35                  40                  45


Glu Ala Pro Leu Asn Asn Phe Ser Val Ala Gln Cys Gln Leu Met Lys 
    50                  55                  60


Thr Glu Arg Pro Arg Pro Asn Thr Phe Ile Ile Arg Cys Leu Gln Trp 
65                  70                  75                  80


Thr Thr Val Ile Glu Arg Thr Phe His Val Glu Thr Pro Glu Glu Arg 
                85                  90                  95


Glu Glu Trp Thr Thr Ala Ile Gln Thr Val Ala Asp Gly Leu Lys Lys 
            100                 105                 110


Gln Glu Glu Glu Glu Met Asp Phe Arg Ser Gly Ser Pro Ser Asp Asn 
        115                 120                 125


Ser Gly Ala Glu Glu Met Glu Val Ser Leu Ala Lys Pro Lys His Arg 
    130                 135                 140


Val Thr Met Asn Glu Phe Glu Tyr Leu Lys Leu Leu Gly Lys Gly Thr 
145                 150                 155                 160


Phe Gly Lys Val Ile Leu Val Lys Glu Lys Ala Thr Gly Arg Tyr Tyr 
                165                 170                 175


Ala Met Lys Ile Leu Lys Lys Glu Val Ile Val Ala Lys Asp Glu Val 
            180                 185                 190


Ala His Thr Leu Thr Glu Asn Arg Val Leu Gln Asn Ser Arg His Pro 
        195                 200                 205


Phe Leu Thr Ala Leu Lys Tyr Ser Phe Gln Thr His Asp Arg Leu Cys 
    210                 215                 220


Phe Val Met Glu Tyr Ala Asn Gly Gly Glu Leu Phe Phe His Leu Ser 
225                 230                 235                 240


Arg Glu Arg Val Phe Ser Glu Asp Arg Ala Arg Phe Tyr Gly Ala Glu 
                245                 250                 255


Ile Val Ser Ala Leu Asp Tyr Leu His Ser Glu Lys Asn Val Val Tyr 
            260                 265                 270


Arg Asp Leu Lys Leu Glu Asn Leu Met Leu Asp Lys Asp Gly His Ile 
        275                 280                 285


Lys Ile Thr Asp Phe Gly Leu Cys Lys Glu Gly Ile Lys Asp Gly Ala 
    290                 295                 300


Thr Met Lys Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val 
305                 310                 315                 320


Leu Glu Asp Asn Asp Tyr Gly Arg Ala Val Asp Trp Trp Gly Leu Gly 
                325                 330                 335


Val Val Met Tyr Glu Met Met Cys Gly Arg Leu Pro Phe Tyr Asn Gln 
            340                 345                 350


Asp His Glu Lys Leu Phe Glu Leu Ile Leu Met Glu Glu Ile Arg Phe 
        355                 360                 365


Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser Leu Leu Ser Gly Leu Leu 
    370                 375                 380


Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly Gly Ser Glu Asp Ala Lys 
385                 390                 395                 400


Glu Ile Met Gln His Arg Phe Phe Ala Gly Ile Val Trp Gln His Val 
                405                 410                 415


Tyr Glu Lys Lys Leu Ser Pro Pro Phe Lys Pro Gln Val Thr Ser Glu 
            420                 425                 430


Thr Asp Thr Arg Tyr Phe Asp Glu Glu Phe Thr Ala Gln Met Ile Thr 
        435                 440                 445


Ile Thr Pro Pro Asp Gln Asp Asp Ser Met Glu Cys Val Asp Ser Glu 
    450                 455                 460


Arg Arg Pro His Phe Pro Gln Phe Ser Tyr Ser Ala Ser Gly Thr Ala 
465                 470                 475                 480


<210>  8746
<211>  2858
<212>  DNA
<213>  Homo sapiens

<400>  8746
cggcaggacc gagcgcggca ggcggctggc ccagcgcacg cagcgcggcc cgaagacggg     60

agcaggcggc cgagcaccga gcgctgggca ccgggcaccg agcggcggcg gcacgcgagg    120

cccggccccg agcagcgccc ccgcccgccg cggcctccag cccggccccg cccagcgccg    180

gcccgcgggg atgcggagcg gcgggcgccg gaggccgcgg cccggctagg cccgcgctcg    240

cgcccggacg cggcggcccg gggcttaggg aaggccgagc cagcctgggt caaagaagtc    300

aaaggggctg cctggaggag gcagcctgtc agctggtgca tcagaggctg tggccaggcc    360

agctgggctc ggggagcgcc agcctgagag gagcgcgtga gcgtcgcggg agcctcgggc    420

accatgagcg acgtggctat tgtgaaggag ggttggctgc acaaacgagg ggagtacatc    480

aagacctggc ggccacgcta cttcctcctc aagaatgatg gcaccttcat tggctacaag    540

gagcggccgc aggatgtgga ccaacgtgag gctcccctca acaacttctc tgtggcgcag    600

tgccagctga tgaagacgga gcggccccgg cccaacacct tcatcatccg ctgcctgcag    660

tggaccactg tcatcgaacg caccttccat gtggagactc ctgaggagcg ggaggagtgg    720

acaaccgcca tccagactgt ggctgacggc ctcaagaagc aggaggagga ggagatggac    780

ttccggtcgg gctcacccag tgacaactca ggggctgaag agatggaggt gtccctggcc    840

aagcccaagc accgcgtgac catgaacgag tttgagtacc tgaagctgct gggcaagggc    900

actttcggca aggtgatcct ggtgaaggag aaggccacag gccgctacta cgccatgaag    960

atcctcaaga aggaagtcat cgtggccaag gacgaggtgg cccacacact caccgagaac   1020

cgcgtcctgc agaactccag gcaccccttc ctcacagccc tgaagtactc tttccagacc   1080

cacgaccgcc tctgctttgt catggagtac gccaacgggg gcgagctgtt cttccacctg   1140

tcccgggagc gtgtgttctc cgaggaccgg gcccgcttct atggcgctga gattgtgtca   1200

gccctggact acctgcactc ggagaagaac gtggtgtacc gggacctcaa gctggagaac   1260

ctcatgctgg acaaggacgg gcacattaag atcacagact tcgggctgtg caaggagggg   1320

atcaaggacg gtgccaccat gaagaccttt tgcggcacac ctgagtacct ggcccccgag   1380

gtgctggagg acaatgacta cggccgtgca gtggactggt gggggctggg cgtggtcatg   1440

tacgagatga tgtgcggtcg cctgcccttc tacaaccagg accatgagaa gctttttgag   1500

ctcatcctca tggaggagat ccgcttcccg cgcacgcttg gtcccgaggc caagtccttg   1560

ctttcagggc tgctcaagaa ggaccccaag cagaggcttg gcgggggctc cgaggacgcc   1620

aaggagatca tgcagcatcg cttctttgcc ggtatcgtgt ggcagcacgt gtacgagaag   1680

aagctcagcc cacccttcaa gccccaggtc acgtcggaga ctgacaccag gtattttgat   1740

gaggagttca cggcccagat gatcaccatc acaccacctg accaagatga cagcatggag   1800

tgtgtggaca gcgagcgcag gccccacttc ccccagttct cctactcggc cagcggcacg   1860

gcctgaggcg gcggtggact gcgctggacg atagcttgga gggatggaga ggcggcctcg   1920

tgccatgatc tgtatttaat ggtttttatt tctcgggtgc atttgagaga agccacgctg   1980

tcctctcgag cccagatgga aagacgtttt tgtgctgtgg gcagcaccct cccccgcagc   2040

ggggtaggga agaaaactat cctgcgggtt ttaatttatt tcatccagtt tgttctccgg   2100

gtgtggcctc agccctcaga acaatccgat tcacgtaggg aaatgttaag gacttctgca   2160

gctatgcgca atgtggcatt ggggggccgg gcaggtcctg cccatgtgtc ccctcactct   2220

gtcagccagc cgccctgggc tgtctgtcac cagctatctg tcatctctct ggggccctgg   2280

gcctcagttc aacctggtgg caccagatgc aacctcacta tggtatgctg gccagcaccc   2340

tctcctgggg gtggcaggca cacagcagcc ccccagcact aaggccgtgt ctctgaggac   2400

gtcatcggag gctgggcccc tgggatggga ccagggatgg gggatgggcc agggtttacc   2460

cagtgggaca gaggagcaag gtttaaattt gttattgtgt attatgttgt tcaaatgcat   2520

tttgggggtt tttaatcttt gtgacaggaa agccctcccc cttccccttc tgtgtcacag   2580

ttcttggtga ctgtcccacc gggagcctcc ccctcagatg atctctccac ggtagcactt   2640

gaccttttcg acgcttaacc tttccgctgt cgccccaggc cctccctgac tccctgtggg   2700

ggtggccatc cctgggcccc tccacgcctc ctggccagac gctgccgctg ccgctgcacc   2760

acggcgtttt tttacaacat tcaactttag tatttttact attataatat aatatggaac   2820

cttccctcca aattcttcaa taaaagttgc ttttcaaa                           2858


<210>  8747
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  8747

Met Ser Asp Val Ala Ile Val Lys Glu Gly Trp Leu His Lys Arg Gly 
1               5                   10                  15


Glu Tyr Ile Lys Thr Trp Arg Pro Arg Tyr Phe Leu Leu Lys Asn Asp 
            20                  25                  30


Gly Thr Phe Ile Gly Tyr Lys Glu Arg Pro Gln Asp Val Asp Gln Arg 
        35                  40                  45


Glu Ala Pro Leu Asn Asn Phe Ser Val Ala Gln Cys Gln Leu Met Lys 
    50                  55                  60


Thr Glu Arg Pro Arg Pro Asn Thr Phe Ile Ile Arg Cys Leu Gln Trp 
65                  70                  75                  80


Thr Thr Val Ile Glu Arg Thr Phe His Val Glu Thr Pro Glu Glu Arg 
                85                  90                  95


Glu Glu Trp Thr Thr Ala Ile Gln Thr Val Ala Asp Gly Leu Lys Lys 
            100                 105                 110


Gln Glu Glu Glu Glu Met Asp Phe Arg Ser Gly Ser Pro Ser Asp Asn 
        115                 120                 125


Ser Gly Ala Glu Glu Met Glu Val Ser Leu Ala Lys Pro Lys His Arg 
    130                 135                 140


Val Thr Met Asn Glu Phe Glu Tyr Leu Lys Leu Leu Gly Lys Gly Thr 
145                 150                 155                 160


Phe Gly Lys Val Ile Leu Val Lys Glu Lys Ala Thr Gly Arg Tyr Tyr 
                165                 170                 175


Ala Met Lys Ile Leu Lys Lys Glu Val Ile Val Ala Lys Asp Glu Val 
            180                 185                 190


Ala His Thr Leu Thr Glu Asn Arg Val Leu Gln Asn Ser Arg His Pro 
        195                 200                 205


Phe Leu Thr Ala Leu Lys Tyr Ser Phe Gln Thr His Asp Arg Leu Cys 
    210                 215                 220


Phe Val Met Glu Tyr Ala Asn Gly Gly Glu Leu Phe Phe His Leu Ser 
225                 230                 235                 240


Arg Glu Arg Val Phe Ser Glu Asp Arg Ala Arg Phe Tyr Gly Ala Glu 
                245                 250                 255


Ile Val Ser Ala Leu Asp Tyr Leu His Ser Glu Lys Asn Val Val Tyr 
            260                 265                 270


Arg Asp Leu Lys Leu Glu Asn Leu Met Leu Asp Lys Asp Gly His Ile 
        275                 280                 285


Lys Ile Thr Asp Phe Gly Leu Cys Lys Glu Gly Ile Lys Asp Gly Ala 
    290                 295                 300


Thr Met Lys Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val 
305                 310                 315                 320


Leu Glu Asp Asn Asp Tyr Gly Arg Ala Val Asp Trp Trp Gly Leu Gly 
                325                 330                 335


Val Val Met Tyr Glu Met Met Cys Gly Arg Leu Pro Phe Tyr Asn Gln 
            340                 345                 350


Asp His Glu Lys Leu Phe Glu Leu Ile Leu Met Glu Glu Ile Arg Phe 
        355                 360                 365


Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser Leu Leu Ser Gly Leu Leu 
    370                 375                 380


Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly Gly Ser Glu Asp Ala Lys 
385                 390                 395                 400


Glu Ile Met Gln His Arg Phe Phe Ala Gly Ile Val Trp Gln His Val 
                405                 410                 415


Tyr Glu Lys Lys Leu Ser Pro Pro Phe Lys Pro Gln Val Thr Ser Glu 
            420                 425                 430


Thr Asp Thr Arg Tyr Phe Asp Glu Glu Phe Thr Ala Gln Met Ile Thr 
        435                 440                 445


Ile Thr Pro Pro Asp Gln Asp Asp Ser Met Glu Cys Val Asp Ser Glu 
    450                 455                 460


Arg Arg Pro His Phe Pro Gln Phe Ser Tyr Ser Ala Ser Gly Thr Ala 
465                 470                 475                 480


<210>  8748
<211>  2780
<212>  DNA
<213>  Homo sapiens

<400>  8748
cggcggcggc aggaccgagc gcggcaggcg gctggcccag cgcacgcagc gcggcccgaa     60

gacgggagca ggcggccgag caccgagcgc tgggcaccgg gcaccgagcg gcggcggcac    120

gcgaggcccg gccccgagca gcgcccccgc ccgccgcggc ctccagcccg gccccgccca    180

gcgccggccc gcggggatgc ggagcggcgg gcgccggagg ccgcggcccg gctaggcccg    240

cgctcgcgcc cggacgcggc ggcccgaggc tgtggccagg ccagctgggc tcggggagcg    300

ccagcctgag aggagcgcgt gagcgtcgcg ggagcctcgg gcaccatgag cgacgtggct    360

attgtgaagg agggttggct gcacaaacga ggggagtaca tcaagacctg gcggccacgc    420

tacttcctcc tcaagaatga tggcaccttc attggctaca aggagcggcc gcaggatgtg    480

gaccaacgtg aggctcccct caacaacttc tctgtggcgc agtgccagct gatgaagacg    540

gagcggcccc ggcccaacac cttcatcatc cgctgcctgc agtggaccac tgtcatcgaa    600

cgcaccttcc atgtggagac tcctgaggag cgggaggagt ggacaaccgc catccagact    660

gtggctgacg gcctcaagaa gcaggaggag gaggagatgg acttccggtc gggctcaccc    720

agtgacaact caggggctga agagatggag gtgtccctgg ccaagcccaa gcaccgcgtg    780

accatgaacg agtttgagta cctgaagctg ctgggcaagg gcactttcgg caaggtgatc    840

ctggtgaagg agaaggccac aggccgctac tacgccatga agatcctcaa gaaggaagtc    900

atcgtggcca aggacgaggt ggcccacaca ctcaccgaga accgcgtcct gcagaactcc    960

aggcacccct tcctcacagc cctgaagtac tctttccaga cccacgaccg cctctgcttt   1020

gtcatggagt acgccaacgg gggcgagctg ttcttccacc tgtcccggga gcgtgtgttc   1080

tccgaggacc gggcccgctt ctatggcgct gagattgtgt cagccctgga ctacctgcac   1140

tcggagaaga acgtggtgta ccgggacctc aagctggaga acctcatgct ggacaaggac   1200

gggcacatta agatcacaga cttcgggctg tgcaaggagg ggatcaagga cggtgccacc   1260

atgaagacct tttgcggcac acctgagtac ctggcccccg aggtgctgga ggacaatgac   1320

tacggccgtg cagtggactg gtgggggctg ggcgtggtca tgtacgagat gatgtgcggt   1380

cgcctgccct tctacaacca ggaccatgag aagctttttg agctcatcct catggaggag   1440

atccgcttcc cgcgcacgct tggtcccgag gccaagtcct tgctttcagg gctgctcaag   1500

aaggacccca agcagaggct tggcgggggc tccgaggacg ccaaggagat catgcagcat   1560

cgcttctttg ccggtatcgt gtggcagcac gtgtacgaga agaagctcag cccacccttc   1620

aagccccagg tcacgtcgga gactgacacc aggtattttg atgaggagtt cacggcccag   1680

atgatcacca tcacaccacc tgaccaagat gacagcatgg agtgtgtgga cagcgagcgc   1740

aggccccact tcccccagtt ctcctactcg gccagcggca cggcctgagg cggcggtgga   1800

ctgcgctgga cgatagcttg gagggatgga gaggcggcct cgtgccatga tctgtattta   1860

atggttttta tttctcgggt gcatttgaga gaagccacgc tgtcctctcg agcccagatg   1920

gaaagacgtt tttgtgctgt gggcagcacc ctcccccgca gcggggtagg gaagaaaact   1980

atcctgcggg ttttaattta tttcatccag tttgttctcc gggtgtggcc tcagccctca   2040

gaacaatccg attcacgtag ggaaatgtta aggacttctg cagctatgcg caatgtggca   2100

ttggggggcc gggcaggtcc tgcccatgtg tcccctcact ctgtcagcca gccgccctgg   2160

gctgtctgtc accagctatc tgtcatctct ctggggccct gggcctcagt tcaacctggt   2220

ggcaccagat gcaacctcac tatggtatgc tggccagcac cctctcctgg gggtggcagg   2280

cacacagcag ccccccagca ctaaggccgt gtctctgagg acgtcatcgg aggctgggcc   2340

cctgggatgg gaccagggat gggggatggg ccagggttta cccagtggga cagaggagca   2400

aggtttaaat ttgttattgt gtattatgtt gttcaaatgc attttggggg tttttaatct   2460

ttgtgacagg aaagccctcc cccttcccct tctgtgtcac agttcttggt gactgtccca   2520

ccgggagcct ccccctcaga tgatctctcc acggtagcac ttgacctttt cgacgcttaa   2580

cctttccgct gtcgccccag gccctccctg actccctgtg ggggtggcca tccctgggcc   2640

cctccacgcc tcctggccag acgctgccgc tgccgctgca ccacggcgtt tttttacaac   2700

attcaacttt agtattttta ctattataat ataatatgga accttccctc caaattcttc   2760

aataaaagtt gcttttcaaa                                               2780


<210>  8749
<211>  480
<212>  PRT
<213>  Homo sapiens

<400>  8749

Met Ser Asp Val Ala Ile Val Lys Glu Gly Trp Leu His Lys Arg Gly 
1               5                   10                  15


Glu Tyr Ile Lys Thr Trp Arg Pro Arg Tyr Phe Leu Leu Lys Asn Asp 
            20                  25                  30


Gly Thr Phe Ile Gly Tyr Lys Glu Arg Pro Gln Asp Val Asp Gln Arg 
        35                  40                  45


Glu Ala Pro Leu Asn Asn Phe Ser Val Ala Gln Cys Gln Leu Met Lys 
    50                  55                  60


Thr Glu Arg Pro Arg Pro Asn Thr Phe Ile Ile Arg Cys Leu Gln Trp 
65                  70                  75                  80


Thr Thr Val Ile Glu Arg Thr Phe His Val Glu Thr Pro Glu Glu Arg 
                85                  90                  95


Glu Glu Trp Thr Thr Ala Ile Gln Thr Val Ala Asp Gly Leu Lys Lys 
            100                 105                 110


Gln Glu Glu Glu Glu Met Asp Phe Arg Ser Gly Ser Pro Ser Asp Asn 
        115                 120                 125


Ser Gly Ala Glu Glu Met Glu Val Ser Leu Ala Lys Pro Lys His Arg 
    130                 135                 140


Val Thr Met Asn Glu Phe Glu Tyr Leu Lys Leu Leu Gly Lys Gly Thr 
145                 150                 155                 160


Phe Gly Lys Val Ile Leu Val Lys Glu Lys Ala Thr Gly Arg Tyr Tyr 
                165                 170                 175


Ala Met Lys Ile Leu Lys Lys Glu Val Ile Val Ala Lys Asp Glu Val 
            180                 185                 190


Ala His Thr Leu Thr Glu Asn Arg Val Leu Gln Asn Ser Arg His Pro 
        195                 200                 205


Phe Leu Thr Ala Leu Lys Tyr Ser Phe Gln Thr His Asp Arg Leu Cys 
    210                 215                 220


Phe Val Met Glu Tyr Ala Asn Gly Gly Glu Leu Phe Phe His Leu Ser 
225                 230                 235                 240


Arg Glu Arg Val Phe Ser Glu Asp Arg Ala Arg Phe Tyr Gly Ala Glu 
                245                 250                 255


Ile Val Ser Ala Leu Asp Tyr Leu His Ser Glu Lys Asn Val Val Tyr 
            260                 265                 270


Arg Asp Leu Lys Leu Glu Asn Leu Met Leu Asp Lys Asp Gly His Ile 
        275                 280                 285


Lys Ile Thr Asp Phe Gly Leu Cys Lys Glu Gly Ile Lys Asp Gly Ala 
    290                 295                 300


Thr Met Lys Thr Phe Cys Gly Thr Pro Glu Tyr Leu Ala Pro Glu Val 
305                 310                 315                 320


Leu Glu Asp Asn Asp Tyr Gly Arg Ala Val Asp Trp Trp Gly Leu Gly 
                325                 330                 335


Val Val Met Tyr Glu Met Met Cys Gly Arg Leu Pro Phe Tyr Asn Gln 
            340                 345                 350


Asp His Glu Lys Leu Phe Glu Leu Ile Leu Met Glu Glu Ile Arg Phe 
        355                 360                 365


Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser Leu Leu Ser Gly Leu Leu 
    370                 375                 380


Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly Gly Ser Glu Asp Ala Lys 
385                 390                 395                 400


Glu Ile Met Gln His Arg Phe Phe Ala Gly Ile Val Trp Gln His Val 
                405                 410                 415


Tyr Glu Lys Lys Leu Ser Pro Pro Phe Lys Pro Gln Val Thr Ser Glu 
            420                 425                 430


Thr Asp Thr Arg Tyr Phe Asp Glu Glu Phe Thr Ala Gln Met Ile Thr 
        435                 440                 445


Ile Thr Pro Pro Asp Gln Asp Asp Ser Met Glu Cys Val Asp Ser Glu 
    450                 455                 460


Arg Arg Pro His Phe Pro Gln Phe Ser Tyr Ser Ala Ser Gly Thr Ala 
465                 470                 475                 480


<210>  8750
<211>  953
<212>  DNA
<213>  Homo sapiens

<400>  8750
ggcagtgctc tgagggccca ggtccctgtg tcaatctgtg gggccctgtc tcagtttcct     60

ggcagtatgg cagcgtgctg gccgtgcttt aagaggttgg cttcctactg gagctgtggg    120

tgggtggagg tggcagggag gtggggcacc ggggtctgag ctgtctacac ccacagatga    180

cagcatggag tgtgtggaca gcgagcgcag gccccacttc ccccagttct cctactcggc    240

cagcggcacg gcctgaggcg gcggtggact gcgctggacg atagcttgga gggatggaga    300

ggcggcctcg tgccatgatc tgtatttaat ggtttttatt tctcgggtgc atttgagaga    360

agccacgctg tcctctcgag cccagatgga aagacgtttt tgtgctgtgg gcagcaccct    420

cccccgcagc ggggtaggga agaaaactat cctgcgggtt ttaatttatt tcatccagtt    480

tgttctccgg gtgtggcctc agccctcaga acaatccgat tcacgtaggg aaatgttaag    540

gacttctgca gctatgcgca atgtggcatt ggggggccgg gcaggtcctg cccatgtgtc    600

ccctcactct gtcagccagc cgccctgggc tgtctgtcac cagctatctg tcatctctct    660

ggggccctgg gcctcagttc aacctggtgg caccagatgc aacctcacta tggtatgctg    720

gccagcaccc tctcctgggg gtggcaggca cacagcagcc ccccagcact aaggccgtgt    780

ctctgaggac gtcatcggag gctgggcccc tgggcccctc cacgcctcct ggccagacgc    840

tgccgctgcc gctgcaccac ggcgtttttt tacaacattc aactttagta tttttactat    900

tataatataa tatggaacct tccctccaaa ttcttcaata aaagttgctt ttc           953


<210>  8751
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  8751

Met Trp His Trp Gly Ala Gly Gln Val Leu Pro Met Cys Pro Leu Thr 
1               5                   10                  15


Leu Ser Ala Ser Arg Pro Gly Leu Ser Val Thr Ser Tyr Leu Ser Ser 
            20                  25                  30


Leu Trp Gly Pro Gly Pro Gln Phe Asn Leu Val Ala Pro Asp Ala Thr 
        35                  40                  45


Ser Leu Trp Tyr Ala Gly Gln His Pro Leu Leu Gly Val Ala Gly Thr 
    50                  55                  60


Gln Gln Pro Pro Ser Thr Lys Ala Val Ser Leu Arg Thr Ser Ser Glu 
65                  70                  75                  80


Ala Gly Pro Leu Gly Pro Ser Thr Pro Pro Gly Gln Thr Leu Pro Leu 
                85                  90                  95


Pro Leu His His Gly Val Phe Leu Gln His Ser Thr Leu Val Phe Leu 
            100                 105                 110


Leu Leu 



<210>  8752
<211>  985
<212>  DNA
<213>  Homo sapiens

<400>  8752
ggcagtgctc tgagggccca ggtccctgtg tcaatctgtg gggccctgtc tcagtttcct     60

ggcagtatgg cagcgtgctg gccgtgcttt aagaggttgg cttcctactg gagctgtggg    120

tgggtggagg tggcagggag gtggggcacc ggggtctgag ctgtctacac ccacagatga    180

cagcatggag tgtgtggaca gcgagcgcag gccccacttc ccccagttct cctactcggc    240

cagcggcacg gcctgaggcg gcggtggact gcgctggacg atagcttgga gggatggaga    300

ggcggcctcg tgccatgatc tgtatttaat ggtttttatt tctcgggtgc atttgagaga    360

agccacgctg tcctctcgag cccagatgga aagacgtttt tgtgctgtgg gcagcaccct    420

cccccgcagc ggggtaggga agaaaactat cctgcgggtt ttaatttatt tcatccagtt    480

tgttctccgg gtgtggcctc agccctcaga acaatccgat tcacgtaggg aaatgttaag    540

gacttctgca gctatgcgca atgtggcatt ggggggccgg gcaggtcctg cccatgtgtc    600

ccctcactct gtcagccagc cgccctgggc tgtctgtcac cagctatctg tcatctctct    660

ggggccctgg gcctcagttc aacctggtgg caccagatgc aacctcacta tggtatgctg    720

gccagcaccc tctcctgggg gtggcaggca cacagcagcc ccccagcact aaggccgtgt    780

ctctgaggac gtcatcggag gctgggcccc tgggatggga ccagggatgg gggatgggcc    840

agggtttacc cagtgggaca gaggagcaag gtttaaattt gttattgtgt attatgttgt    900

tcaaatgcat tttgggggtt tttaatcttt gtgacaggaa agccctcccc cttccctcca    960

aattcttcaa taaaagttgc ttttc                                          985


<210>  8753
<211>  140
<212>  PRT
<213>  Homo sapiens

<400>  8753

Met Trp His Trp Gly Ala Gly Gln Val Leu Pro Met Cys Pro Leu Thr 
1               5                   10                  15


Leu Ser Ala Ser Arg Pro Gly Leu Ser Val Thr Ser Tyr Leu Ser Ser 
            20                  25                  30


Leu Trp Gly Pro Gly Pro Gln Phe Asn Leu Val Ala Pro Asp Ala Thr 
        35                  40                  45


Ser Leu Trp Tyr Ala Gly Gln His Pro Leu Leu Gly Val Ala Gly Thr 
    50                  55                  60


Gln Gln Pro Pro Ser Thr Lys Ala Val Ser Leu Arg Thr Ser Ser Glu 
65                  70                  75                  80


Ala Gly Pro Leu Gly Trp Asp Gln Gly Trp Gly Met Gly Gln Gly Leu 
                85                  90                  95


Pro Ser Gly Thr Glu Glu Gln Gly Leu Asn Leu Leu Leu Cys Ile Met 
            100                 105                 110


Leu Phe Lys Cys Ile Leu Gly Val Phe Asn Leu Cys Asp Arg Lys Ala 
        115                 120                 125


Leu Pro Leu Pro Ser Lys Phe Phe Asn Lys Ser Cys 
    130                 135                 140


<210>  8754
<211>  7492
<212>  DNA
<213>  Homo sapiens

<400>  8754
ccaccagggg ctggccttag gttccatccc catgtgctgc atcggcccct cccctccaag     60

tagctctgcc ctcctttctt tgaggcctgc ggtcctccga ctcccttgaa cttgctggac    120

ccccaggttc tggtccaggg tctgggagga ggttaaatgc agggaatccg tccccaggct    180

gggcagggaa ggactcccac ccttggtgcc tgcacgtata aggggaggtg gggtcagtct    240

ggcaccctgg ctgctaggtg gtctgtggcc agcaaaccgt gccctgaagc ttctagttgg    300

gaggggcaga ggccttgccc tgcaaagccc caggctgagg ggctggggtt ggggtggggt    360

ttaccaggac ctggttcctg taagccgagg tctccttccc tggctcttcc agcctcaagc    420

cagcagtagc agggcagcct gatagagtag ggcaccccag gggtgagggg agaccaggaa    480

ggcagacacc cctgtctcct gacagcctcg taaccatgca ggagactcac tgtgacttgt    540

cccacaccct ccccagtgtc tcctcggttg gggctggggg cttcagggat cagggagagg    600

ctgggtgcca gcagcgtgcc tggtggcacc tgggacaggg ccttgctggg ggtgggtgct    660

gtgggtgtgc tcgccaggcc gaggcattgg gaaggaacga ggtggggagc tctctggaga    720

ggcacacggg tgggtaccag ctggaggtgt tgcctgagca gctggcaagg ctggggcctt    780

cagattaggc cataggtgag tggcctggag cgcctggcca aggagcagag ctgggcaggg    840

gccaggggct gtgctgggcc tctgtccggg gcttttctcc ggggaacggt tccggggcag    900

tgggctcgag actctggccc tggggattgc atactggggc agatcggacc atccaggagc    960

gagtgggagg tgggtgtgcc ggggcttcac accggtttcc acttctctgg cctgtgttga   1020

cacaggccac cctccccacc aggctggtcc cgagccccct cctggccccc aggcctggaa   1080

gacagcttcc ttgctgcctg gccaggcccc cttgtggttg ccagggcctc gatgctggaa   1140

tgtcagaggc cccccactgg cccctcagcc tcctcctgct ttgcacaggc tgggccagag   1200

cctgccacgg agccccagcg gctacacact ccactcactc acacctctca gggccccgca   1260

cgttcccaca gccctcaggg tgtacgtgct gtaggtgtgg ctgtgcccca ggtatgtgtt   1320

ccccaggtgt gcttgtgccc caggtgtggc tgtgccccag gtgtgcgtgt gccccaggtg   1380

ttcgtgtgcc ccagatgtgg ctaggtgtct agatgtgttc tagatgtctg tgtattccag   1440

tgtggctgtg tcccaggtgt gcgtgtgccc caggtgtgtg cctcaggtgt gcgtgtgccc   1500

caggtgtggc tttgcctcca gtgtgtgtgt gccccagatg tatgtgtgcc ccaggtgtgg   1560

ctgtgcccca ggtgtgcctg tgccccaggt gtggctgtgc cccaggtgtg cctgtgcccc   1620

aggtgtgggt gtgccccagg tgtgggtgtg ctccaggtgg ctgtatttcc caggtactca   1680

gggtgaggtt gggaaaaaag caggacattt ctacactagg tgggacaagc aggtttctgg   1740

ggtgcccccc tcatgccagc ccctctgtgg gatctccata cccctcatcc tctgaggcct   1800

ggcgcacggc ggggctcaga gactgaagga aggactgtag gagtggacga tggtgggggt   1860

ttgacctgac gccgggccag atgccctgtg tggctgcctc agcctggagt agagtgtctg   1920

agctggaaca ggggtcctag ccccactctg tgaggcgaga aactgaggct tggagagagg   1980

aagagatggg gcttcccagg acctggtggg tggtatgcaa ggggagctgg ctggtgcagc   2040

gggggctgtg gtgagggccc tgggaggggc agggggatgc acgcagacag aggctctgcc   2100

tgcccgcaga gtgccagctg atgaagacgg agcggccccg gcccaacacc ttcatcatcc   2160

gctgcctgca gtggaccact gtcatcgaac gcaccttcca tgtggagact cctgaggagc   2220

ggtacgtggg ctgtggcggc caggccaggc acttgggcag ccccagcgct taggagggac   2280

acggggatgg cggggtgctg gcacctctgc ctgtagccat cctcactccc cagtgctccc   2340

aggccctcct cagagcccag tttggaaact ggcccagtcc tgcctgtggg gtttgggtgg   2400

ggaaactgag gctggagata aaaactggct agggaccggg tgcagtggct cacgtctata   2460

atctcggcac tttgggaggc cgaggtgcgc agatcacttg agaccaggag tttgagacta   2520

gcctgccaac atggtgaaac ccccgtctct actaaaaata taaaacttag ctgggtgtgg   2580

tggtgcacac ctgtaatccc ggctacttgg gaggctgagg cacaagaatc gcttgaaccc   2640

gagaggcaga ggctgcagga gccgagattt taccactgca ctccagccag ggcgatagag   2700

caagactccg tctcaaaaaa agaaaaaccc ggtggagagg gccagtcctc cttggggggc   2760

ggagtcctgc ttgggaggcg gagtcctgct tggggggggc ggagtcctgc tggggggcgg   2820

agtcctgctg ggggttggag tccggttgtg gggacagagt cctgctgggg ggctaagcct   2880

gggtgtcccc cacgtccaag agggcttcgt gaccctgagt gtatgtggcc agaccaggtc   2940

aagtggtggc ctcctcaggg ctgtctctgg gaaccccgac agctgtggaa ccacgcttgt   3000

gaggctggcg ggtgggtgaa agacgtgggg tggagctcct gatctggtac aggcctgcag   3060

cctcacctga cctcctgcag ggaggagtgg acaaccgcca tccagactgt ggctgacggc   3120

ctcaagaagc aggaggagga ggagatggac ttccggtcgg gctcacccag tgacaactca   3180

ggggctgaag agatggaggt gtccctggcc aagcccaagc accgcgtggt gaggcctgtc   3240

cccacttctg cctgtgcctg gggctgcctt ggactgtgga gggctgggtg ggtcatgggg   3300

tcccagctcg gcccaggaga cactcagcac tccacggcat ctccacctag gccggttttc   3360

catgtagggc gcagctgctt cccaggtggg tcctcttccc catgtcagag gaaaactggg   3420

gttgctgagc cctgccaggc ttgggcaatg ttaccccacc cttccctgaa ccccatgctc   3480

tgagctgggg ccgcagccat gtgttccctg taagcctgga ctccccgctg agcccagtag   3540

gccaccaggt gtgaagtgga cgcctctcct ggctctgcct ccgactctgg ggcccctcat   3600

gccaccccac gcatgccgac cagctgggca ctgttggcag cgccgcttgc tgaccctggt   3660

gcctgcccat agaccatgaa cgagtttgag tacctgaagc tgctgggcaa gggcactttc   3720

ggcaaggtga tcctggtgaa ggagaaggcc acaggccgct actacgccat gaagatcctc   3780

aagaaggaag tcatcgtggc caaggtgggg ccggggcggt ggggcagggt ggagatgagg   3840

gtgcggggtg gcagctcacc cagccctgct ttacaggacg aggtggccca cacactcacc   3900

gagaaccgcg tcctgcagaa ctccaggcac cccttcctca cagtgagtgg gagcccagat   3960

ggggctgaag ggctggggcc aggtagcgac tcctggggct gtctctaggg gacgatgtcc   4020

tgtcttcttg ggcacgtgag ggctttacac accgtggact ccgccgctgg tgagacaggc   4080

ctgccctgga gggtcaggct gtggaggtgc ccagtgtggg ctaggggctg tgctcgctgc   4140

tcccgtgtgc gggcaggtgg gtggggcagg tggccctggt cttccttgca ctctgccgag   4200

gctccaggag gccccagctc cccatgccct gcagccctgc ctgccaggct tttgttgagg   4260

cccgggctct gtcctgcaga acctgttctg gggacttggc ccaggaggta tttactgtga   4320

agggggccag ggtccagcca cttggttagt tccaggtcac tgtgtttggg gacgattctc   4380

ctgcagatgg ggcctttgct ttaaaagcac agtcgcctgt ggtggaaggc gggagggtgg   4440

gtctcgcctg ggagggtgtg tcctcccttt gcgaaggccc tggtgctggg agcactgtcc   4500

cctgctgagg tcccaactca ccctggagga cctgagccca ggccaccttg ctcacctttc   4560

aaacactcct tggcacctca ggggctgccg gggcccagcc tgatggtggc gtggcatgag   4620

gcagtgtggt gtggggcagt gtggtgtggg gcagcgtggc atgggggcag tgtgatgtgg   4680

gggtgtatgg tgtggggcag tgtgatgggg tgtgtggtgt ggggcagtgt ggtatcgggc   4740

ggtgtggtat caggcagcgt ggtgtcgggc agtgtggtgt ggggctacgg gcggtgtggt   4800

atcaggcgac gtggtatcaa gcagcgtggt gtcgggcagc gtggtgcggg gctgccgtcc   4860

tgcctgtggg gccgcagttc cagctcccct tccttgcagg ccctgaagta ctctttccag   4920

acccacgacc gcctctgctt tgtcatggag tacgccaacg ggggcgaggt aggggctggg   4980

gctgcggggg atggacttcg cggcctgtgg gccgcccatg gtggggccgg tccttcccgg   5040

agcctcggct actctccatg gcaccagacg gtgctccctg ctgggtgggt ggtgtgatgc   5100

ctgcccaggc agctgcctgc tgtggggtga cttgttcctg ctgagttagg gcttctgaga   5160

ctttccaggc ccccgtgccc tctggtggct ggtcccttcc ctgtgcaatg ccgagacccg   5220

gtctgagaaa ccccagccct gcaggccatg ggggcagagg cccgagccac ggctgtgcct   5280

caggttgcgc ctcccgcagc tgttcttcca cctgtcccgg gagcgtgtgt tctccgagga   5340

ccgggcccgc ttctatggcg ctgagattgt gtcagccctg gactacctgc actcggagaa   5400

gaacgtggtg taccgggacc tcaagctgga gaacctcatg ctggacaagg acgggcacat   5460

taagatcaca gacttcgggc tgtgcaagga ggggatcaag gacggtgcca ccatgaagac   5520

cttttgcggc acacctgagt acctggcccc cgaggtgtgc gccccacctg cgtgcatacg   5580

cgttgctgcg tccccacgtc ctgagcacac gcaatgctgt gtcctctctg tgccccaagc   5640

acgtcacacc tcccccggca gtgtcccgga caccccttga tgccgagtcc tgcccatctg   5700

ccacccgtgc aggtgctgga ggacaatgac tacggccgtg cagtggactg gtgggggctg   5760

ggcgtggtca tgtacgagat gatgtgcggt cgcctgccct tctacaacca ggaccatgag   5820

aagctttttg agctcatcct catggaggag atccgcttcc cgcgcacgct tggtcccgag   5880

gccaagtcct tgctttcagg gctgctcaag aaggacccca agcagaggct tggcgggggc   5940

tccgaggacg ccaaggagat catgcagcat cgcttctttg ccggtatcgt gtggcagcac   6000

gtgtacgaga agaaggtgcg gctgctcccc gcatattcac gcgcacgcat gctccccaca   6060

tatccacact cacgcatgca cgtggcacgc tcgccagatt tcccacacac tcgccctcac   6120

ctcaggagcc tgctgcagtc ctggtacaag gagggccttg ctgcaccaac ctcagcgcct   6180

ggtgctcaga ggctctggca ctgccgggtt ccaccaggaa actggcctgg tcctcatttc   6240

ctcctcccct cggaggtgtg tcacactctg agtttcctcc tcccctcgga ggtgtgtcac   6300

actctgagtg ccagccttgg ggttcccttc cctgacgctg tgcagtgaag gctggctggt   6360

ggtggaccag gggtgctgcc ccttggcctc cacgagttcc tcctgtttga cctcaatccc   6420

ttctgccgca aggagagccc agccctattt ctggctgtgc agggacaggg acagcaccta   6480

cttttctggc acatggggga gtccgccctg gagggaggca gctctttctg catgagtcgc   6540

catcctgggt gctcatcttt cagggaccct aggagccctg gccatcaccc cagctgatgg   6600

ggtctgccag ctgggttcgg aagcctgcac tctgagatgc tgggtgccct gtcaccaggt   6660

gtgcttctgc cccgttccca gcctgcccct cccctgaatg cctgtcctag gctgtgtgca   6720

gctggtcggg ctgggcagcc ctgggaccca gctgggcacc tgttctccca ttaacacagg   6780

gtgccctggt cctggtcccc gttcctgcct tgaggcctgc caccctcctg ccctgccctc   6840

caagggtatg gggggcctgg gcagtgctca acctctgccc agccttgacc agagaccttg   6900

ctaattgaca atggacaatg ctggtgccca gcccagactc tggggtgggg cagtgcttga   6960

gggggtcctt gactgtggga cctgaggggc tctctggcag ctcctcacgt gtgcacatca   7020

ccttatagtc acccttcatc ctgggtcatt gagagtcctg tctgcagcca gatgccagca   7080

ggctgtggtc ctgtagtccc tgagccatgg aggcagggtg ggctcatcct gtgcaccttg   7140

ttccacagtc tccctctttc ccaatttaca agaagaccaa taagaaaaat aagaaaacaa   7200

gaaagaaaaa ggaaaaataa agttatcacc tcctggtagc agggagggtc tctcagagct   7260

gggctgcact acctcctgtc gcctgctggg gctgctgtga gggcagcttt gcgtctcagc   7320

tgttgagggt tgtctccgtg ctcctgcacc cctcatgtcc ctccctccca gagctgcctc   7380

tgtggggggc tggtggcttg ctgctctctg acatcagtcc tgcctggaga ccccttggag   7440

atccaggtgc tttgaaggtc ttgagcacac ttgagggtgt gctgggagtg gg           7492


<210>  8755
<211>  244
<212>  PRT
<213>  Homo sapiens

<400>  8755

Met Leu Cys Pro Leu Cys Ala Pro Ser Thr Ser His Leu Pro Arg Gln 
1               5                   10                  15


Cys Pro Gly His Pro Leu Met Pro Ser Pro Ala His Leu Pro Pro Val 
            20                  25                  30


Gln Val Leu Glu Asp Asn Asp Tyr Gly Arg Ala Val Asp Trp Trp Gly 
        35                  40                  45


Leu Gly Val Val Met Tyr Glu Met Met Cys Gly Arg Leu Pro Phe Tyr 
    50                  55                  60


Asn Gln Asp His Glu Lys Leu Phe Glu Leu Ile Leu Met Glu Glu Ile 
65                  70                  75                  80


Arg Phe Pro Arg Thr Leu Gly Pro Glu Ala Lys Ser Leu Leu Ser Gly 
                85                  90                  95


Leu Leu Lys Lys Asp Pro Lys Gln Arg Leu Gly Gly Gly Ser Glu Asp 
            100                 105                 110


Ala Lys Glu Ile Met Gln His Arg Phe Phe Ala Gly Ile Val Trp Gln 
        115                 120                 125


His Val Tyr Glu Lys Lys Val Arg Leu Leu Pro Ala Tyr Ser Arg Ala 
    130                 135                 140


Arg Met Leu Pro Thr Tyr Pro His Ser Arg Met His Val Ala Arg Ser 
145                 150                 155                 160


Pro Asp Phe Pro His Thr Arg Pro His Leu Arg Ser Leu Leu Gln Ser 
                165                 170                 175


Trp Tyr Lys Glu Gly Leu Ala Ala Pro Thr Ser Ala Pro Gly Ala Gln 
            180                 185                 190


Arg Leu Trp His Cys Arg Val Pro Pro Gly Asn Trp Pro Gly Pro His 
        195                 200                 205


Phe Leu Leu Pro Ser Glu Val Cys His Thr Leu Ser Phe Leu Leu Pro 
    210                 215                 220


Ser Glu Val Cys His Thr Leu Ser Ala Ser Leu Gly Val Pro Phe Pro 
225                 230                 235                 240


Asp Ala Val Gln 



<210>  8756
<211>  592
<212>  DNA
<213>  Homo sapiens

<400>  8756
actccccgct gagcccagta ggccaccagg tgtgaagtgg acgcctctcc tggctctgcc     60

tccgactctg gggcccctca tgccacccca cgcatgccga ccagctgggc actgttggca    120

gcgccgcttg ctgaccctgg tgcctgccca tagaccatga acgagtttga gtacctgaag    180

ctgctgggca agggcacttt cggcaaggtg atcctggtga aggagaaggc cacaggccgc    240

tactacgcca tgaagatcct caagaaggaa gtcatcgtgg ccaaggacga ggtggcccac    300

acactcaccg agaaccgcgt cctgcagaac tccaggcacc ccttcctcac agtgagtggg    360

agcccagatg gggctgaagg gctggggcca ggtagcgact cctggggctg tctctagggg    420

acgatgtcct gtcttcttgg gcacgtgagg gctttacaca ccgtggactc cgccgctggt    480

gagacaggcc tgccctggag ggtcaggctg tggaggtgcc cagtgtgggc taggggctgt    540

gctcgctgct cccgtgtgcg ggcaggtggg tggggcaggt ggccctggtc tt            592


<210>  8757
<211>  86
<212>  PRT
<213>  Homo sapiens

<400>  8757

Met Asn Glu Phe Glu Tyr Leu Lys Leu Leu Gly Lys Gly Thr Phe Gly 
1               5                   10                  15


Lys Val Ile Leu Val Lys Glu Lys Ala Thr Gly Arg Tyr Tyr Ala Met 
            20                  25                  30


Lys Ile Leu Lys Lys Glu Val Ile Val Ala Lys Asp Glu Val Ala His 
        35                  40                  45


Thr Leu Thr Glu Asn Arg Val Leu Gln Asn Ser Arg His Pro Phe Leu 
    50                  55                  60


Thr Val Ser Gly Ser Pro Asp Gly Ala Glu Gly Leu Gly Pro Gly Ser 
65                  70                  75                  80


Asp Ser Trp Gly Cys Leu 
                85


<210>  8758
<211>  416
<212>  DNA
<213>  Homo sapiens

<400>  8758
cggcaggacc gagcgcggca ggcggctggc ccagcgcacg cagcgcggcc cgaagacggg     60

agcaggcggc cgagcaccga gcgctgggca ccgggcaccg agcggcggcg gcacgcgagg    120

cccggccccg agcagcgccc ccgcccgccg cggcctccag cccggccccg cccagcgccg    180

gcccgcgggg atgcggagcg gcgggcgccg gaggccgcgg cccggctagg cccgcgctcg    240

cgcccggacg cggcggcccg tctggggagc agggaggagc cctgtgccct gtcccaggat    300

ccatgggtag gaacaccatg gacagggaga gcaaacgggg ccatctgtca ccaggggctt    360

agggaaggcc gagccagcct gggtcaaaga agtcaaaggg gctgcctgga ggaggc        416


<210>  8759
<211>  137
<212>  PRT
<213>  Homo sapiens

<400>  8759

Arg Gln Asp Arg Ala Arg Gln Ala Ala Gly Pro Ala His Ala Ala Arg 
1               5                   10                  15


Pro Glu Asp Gly Ser Arg Arg Pro Ser Thr Glu Arg Trp Ala Pro Gly 
            20                  25                  30


Thr Glu Arg Arg Arg His Ala Arg Pro Gly Pro Glu Gln Arg Pro Arg 
        35                  40                  45


Pro Pro Arg Pro Pro Ala Arg Pro Arg Pro Ala Pro Ala Arg Gly Asp 
    50                  55                  60


Ala Glu Arg Arg Ala Pro Glu Ala Ala Ala Arg Leu Gly Pro Arg Ser 
65                  70                  75                  80


Arg Pro Asp Ala Ala Ala Arg Leu Gly Ser Arg Glu Glu Pro Cys Ala 
                85                  90                  95


Leu Ser Gln Asp Pro Trp Val Gly Thr Pro Trp Thr Gly Arg Ala Asn 
            100                 105                 110


Gly Ala Ile Cys His Gln Gly Leu Arg Glu Gly Arg Ala Ser Leu Gly 
        115                 120                 125


Gln Arg Ser Gln Arg Gly Cys Leu Glu 
    130                 135


<210>  8760
<211>  783
<212>  DNA
<213>  Homo sapiens

<400>  8760
ccagtgctgg gcgctggaga caaagagagg ttcagacaag tccgtcagtg aggagcaccc     60

agtccagggt ggttacagac ccataattac agcagtcggg aggcagcaag taagtggggg    120

agcactggac aggcccccgc cctgcagcgg cccaccagcc aaccctcacc tgagcacact    180

ttatccattg atcctgcatg gcttcctcat ttcccctctg atggatgaac tcctaggcat    240

ccctcaaaac ccagttccca catcaccaac tacaggcatc cccagaaaga gcacttcgca    300

tgctcttcct gtgagcagtc ctctgctacc cttccagatg ggccttcctg aggggaggag    360

ggtcctctct gggacctcca ggccaggcag agacccctga cgacctctgt ggaatggatc    420

ccaacatggg tctttccaca gccagcttag acgctctccc cccaggccac ctttctggcc    480

tcccgaggca agggctggac acccacaaag ggttgctttg cactgattgt cttaagctac    540

acttagaatg gcaggaaggc ccactgcctt gtgtctaatg ccaggacagg gaagaccaca    600

ccttacccaa agagggaaat gccccaagta cttagcagga tggaaagcag gccagactcg    660

aggaaggcac cgcaggactc cgagggcagg gctccgagcc gcgcacgcct caggcacagg    720

gggctctgac gacactgagt gggcgtggca acttttcgtc cgtgggaaac gaagtctcct    780

tcc                                                                  783


<210>  8761
<211>  77
<212>  PRT
<213>  Homo sapiens

<400>  8761

Met Ala Gly Arg Pro Thr Ala Leu Cys Leu Met Pro Gly Gln Gly Arg 
1               5                   10                  15


Pro His Leu Thr Gln Arg Gly Lys Cys Pro Lys Tyr Leu Ala Gly Trp 
            20                  25                  30


Lys Ala Gly Gln Thr Arg Gly Arg His Arg Arg Thr Pro Arg Ala Gly 
        35                  40                  45


Leu Arg Ala Ala His Ala Ser Gly Thr Gly Gly Ser Asp Asp Thr Glu 
    50                  55                  60


Trp Ala Trp Gln Leu Phe Val Arg Gly Lys Arg Ser Leu 
65                  70                  75


<210>  8762
<211>  6710
<212>  DNA
<213>  Homo sapiens

<400>  8762
gtgggctcgg cccgggctgc cacgagcgtg cgggcctcgc cgggcatgtc ctaggcggcg     60

gccccgccca gcgctcggcc gggcgggcgg gcgggcgcga gggcagggac cgagccgggc    120

cgagctgggg aacaagccgg ggaccaagcc ggggaccaag ccggggacta aggcgagccg    180

gagaccgagc ccgaacagca gggccagacg ggcccagcca gcaccaagat gagtgccacg    240

tcctggttcc tggtgagcag cagcggcgcc cgccaccggc tccctcggga gctcatcttc    300

gtggggcgtg aggagtgtga gctcatgcta cagtcccgca gcgtggacaa gcagcatgcc    360

gtcatcaact acgaccagga cagggacgag cactgggtga aggacctggg cagcctcaat    420

gggacgtttg tgaatgacat gcgcatcccg gaccagaagt acgtcacgct gaagctcaac    480

gatgtcatcc gcttcggcta cgattccaac atgtatgtgc tggagcgtgt gcagcaccga    540

gtcccggagg aggcactcaa gcatgaaaag tacaccagcc agctgcaggt gagcgtgaag    600

ggtttggcgc ccaagaggag cgaggcactg ccggaacaca caccatactg cgaggcctcg    660

aaccccaggc cggagaaggg ggaccggaga ccaggaacag aggcagcctc ttaccgcaca    720

cccctgtatg ggcagccctc ctggtggggt gaggacgatg gtagcacgct gcctgacgcc    780

cagcgccagg gagagcccta cccagagcgc cccaagggac cagtgcagca ggacggggag    840

ctccacggct tccgcgcccc tgctgagcct cagggctgct cgttccggcg ggagcccagc    900

tacttcgaga tccccacgaa ggagaccccg cagccgtcgc agccccccga ggtgccggca    960

cacgagatgc ccacgaagga tgcagaggca ggtgggggcg gagcggcccc tgtggtgcag   1020

agccacgcct ccttcaccat cgagtttgat gactgcagcc ctggcaagat gaagatcaag   1080

gaccatatca ccaagttttc cctgcgccag cggcggcccc cgggcaagga ggccacacct   1140

ggcgagatgg tgtcggctga gaccaaggtg gccgactggc tggtgcagaa tgacccgagc   1200

ctgctgcacc gggttggccc tggggatgac cgccacagca ccaagagcga cctgcctgtc   1260

cacacccgca ccctgaaggg ccacaagcac gaggacggca cgcagagtga ctcagaggac   1320

cccctggcca aggcggcctc ggccgctggg gtgcccttgg aggccagcgg ggagcaggtg   1380

cggctgcaga ggcagatcaa gcgggacccc caggagctac tacataacca gcaggccttt   1440

gtcatcgagt tcttcgacga ggacacaccc cgaaagaagc gctcccagtc cttcacgcac   1500

agcccgtccg gggaccccaa ggccgacaag cgccgtggcc caacgccggc cgatagggac   1560

cgccccagtg tcccagcccc agtccaggca gggggccgca gctcggggcc acagagggcc   1620

ggctcgctca agcgggagaa gacagaggaa cggctgggca gcccctcgcc cgcctcccga   1680

acccctgccc gccccttcgg aagcgtgggg cgccgctccc gcctggccca ggacttcatg   1740

gcccagtgtc tgcgggagag ctccccggcc gcccggccca gccccgagaa ggttcctccg   1800

gtgctgcccg ctcccctgac accccatggg accagccccg tgggcccccc gaccccaccg   1860

cccgccccca cggaccccca gctgaccaag gcacggaaac aggaggagga cgacagcctc   1920

agtgacgcag ggacatacac catcgagacc gaggcgcagg acacggaggt ggaggaggcc   1980

cggaagatga tcgaccaggt ctttggggtg ttggagtccc ctgaactctc cagggcatct   2040

tcggccacct ttcgcccagt catcagaggg gacagagatg agtctgatga cgggggcgtg   2100

gcccagcgga tggcgctact gcaggagttt gcctcccggc cactgggtgc ggccccccag   2160

gcggagcacc agggcctccc ggtgccgggc tcccctgggg gtcagaagtg ggtgtcccgc   2220

tgggccagcc tggctgacag ctactcagac ccgggcctca cagaggatgg cctgggacgt   2280

agaggcgggg agccggaggg gtccctgcct gtgcgcatgc ggcgacggct ccctcagctg   2340

cccagtgaga gggctgacag ccctgcgggc ccagagagca gcaggaggag tgggcctggg   2400

ccaccggagc tggacagtga gcagcccagc cgcctcttcg gccaggagga gttggatcct   2460

gacagcctca gcgatgccag tgggtcggac gggggccgag gccccgagcc aggggtggag   2520

ccacaggaca gcagacgcag gagcccccag gaggggccca cgtggagcag gggtcggcgc   2580

tcaccaaggg cccccgggga gccaactccc gcctctttct tcattgggga ccagaatggg   2640

gacgctgtgt tatctaggaa accgcttgcg gctccagggg atggggaggg cctagggcag   2700

acagcccagc ccagcccccc agcacgggat ggcgtctatg tcagtgccaa tgggagaatg   2760

gtcatccagc tacggcctgg acggtcccca gaacccgacg gccctgcccc agcctttctc   2820

cggcaagaga gcttcactaa ggagccagcc agtggtcccc cagcgcccgg caagcccccc   2880

cacatctcca gccacccgct tctacaggac ctggccgcta cccgggccgc acgcatggac   2940

ttccactccc aggacaccca cctgatcttg aaggagacgg agacggccct ggcggccctg   3000

gaggcccgac tcctctctaa ttctgtggat gccgagtgtg aggggggcag caccccgagg   3060

ccgccggagg acgccctgtc tggggactcg gacgtggaca cagccagcac cgtcagcctg   3120

cgtagtggca agagcgggcc cagccccaca accccccagc ctctgcgggc acagaaggag   3180

atgtcgccat ccccgccagc tgcacaggac ccgggaggca ccgccctggt cagtgcccgt   3240

gagcagtcct cagagaggca gcatcaccca cttggcccga cggacatggg ccgtggagag   3300

ccggtacggc gctcagccat aaggcgtggc cacaggcccc gagggtccct ggattggccc   3360

agtgaggagc gtggccctgt cctcgcccac ctacccagct cagatgtgat ggcctccaac   3420

cacgaaaccc ctgaggccac cggggcagga cggctaggtt ctcgccggaa accagcggcc   3480

ccaccgccat ccccagctgc ccgggaggag cagagccgta gctcagccag ctcccagaag   3540

gggccgcagg ccttgacccg ctccaacagc ctgtccaccc ctcgccccac acgggcctcc   3600

cggctgaggc gggcccggct gggggacgct tcagacactg aggctgcgga tggtgagcgg   3660

gggtccctgg gcaaccctga gcccgtgggc cggccagctg ctgagcaggc caagaagctg   3720

tcacgcctgg acatcctggc catgccccgg aagcgggccg gctccttcac agggactagt   3780

gaccccgagg cagcccctgc ccgcaccagc ttctctggcc gcagtgtgga gttgtgctgt   3840

gccagccgca agcccaccat ggccgaagca cgggctgtct ccaggaaggc tgccaacaca   3900

gccaccacca cgggtccccg ccagcccttc agcagggccc gctcaggcag tgcccgatac   3960

acctccacca ctcagacccc gagggctggc agctccagcc gggctcgttc ccgggccccc   4020

ggcccccggg acacggacga cgatgaggag gagcctgacc cttatggttt catcgtgcag   4080

acggcagaga ttgcggagat tgccaggctg agccagacgc tggtgaagga cgtggccatc   4140

ctagcccagg agatccacga tgtggctggg gacggtgaca cactgggctc ctcggagcct   4200

gcccacagcg cctccctcag caacatgccc agcacccccg cctcgaccat ctctgcccgg   4260

gaggagctgg tgcagcgcat ccccgaggcc agcctcaact tccagaaggt gccgcccggc   4320

tcgctgaact ctcgggactt tgaccagaac atgaacgaca gctgtgagga cgccctggcc   4380

aacaagacgc ggcctcggaa ccgagaggag gcacggtgat cttcgataac ctgatgctga   4440

acccggtgtc ccagctgtcg caggccatcc gtgagaacac agagcacctt gccgagaaga   4500

tgaagatcct ctttcagaac acagggagag cttgggagga cctggaagcc aggatcaacg   4560

ccgagaacga ggtgcccatc ctgaagacat ctaacaagga aatcagctcc atcctgaagg   4620

aactgaggcg ggtgcagaaa cagctggaag ttatcaatgc catcgtggac cccagtggga   4680

gcctggacct gctcacagga aacaggagct tggccagctc tgcacagccg gggctgggga   4740

agggccgcgt ggctgcccag agcccaccct cacccgcctc agccgaggcc ctgctgccag   4800

ccctgcccct gaggaatttc ccacagcggg ccagctgtgg gcctcccagc ctcccggacc   4860

ccaccttcct ccctgatgcc gagaggttcc tgatctaggc cccagacctg gccaggccag   4920

cctccctgtg cgtgtgcgtc tctgccttcc gtccgccgca cacccgcctg cctggccgca   4980

ggtggttctc cctgaagacc cccacatgtg ccatatccct gtgggcgggt gcctcccacg   5040

cccttgcccc ctcgtcagct cccagccagc accctactca ccctgtccag ccccatggcc   5100

acccccaccc ctgcctcgcc ccctacaggc ctctgggccc agctcctggc caggctgctg   5160

ccaaggtcaa gccctcaagg gcattacccc gcctcctctt catcactgtt atttttgtct   5220

ttagctttaa aggaaagagt tgttggtgcc attgcaggtg ccccctccag gcctgactgg   5280

ctccgccagg cactaacctg ccataaccct ttgtgctggc ctgcggccag gcagaggaag   5340

agaggtcgac tgtggggtca tttggtgcca aacatggagg tgggcaggct cacctgttcc   5400

tgggactgtc tgagatggca gggcacttgc cctggtggct cccacctgac cccaggcctt   5460

ttataggcag gagccccact gcttccagcc tctggtgcca acacagttgc caaacccatt   5520

gagcttgggg ctgccctgtg gaggcctcct gggtatggac caggggcttg ttgagagctg   5580

agccatgcac acaggtgcag acacccccca actcccatgc acacggctag tccaggcgcc   5640

tccacgctgc accgtgagga ctgcagggca tgtccccgtg aggggctatg ggcctctgta   5700

ggtgggcttc caaggtcctg ggtgcagccg ggtgcatggc agcccttctg gcgggggtga   5760

gcgcacgacc aaagtcactg gaagccgggt ttccggaagc tcgcagcttg gcctgcacca   5820

cacgccctcc ccttttggct tcacgccatc aggcctcaag tgggcatggg ggcagggacg   5880

ggcccaggaa ctgttgtttt ctcaggattc tttcagctgg gaacatggca ggtgagcaga   5940

gcttggtgcc tctgccgtgg cccctgctgg ggcagcccgt gttgccggag cctctaagcc   6000

aaagagcccg ttggccgtgg ttggtggggg tggacgtggg ggtgtcccac ctggaccaga   6060

ctggcgtggg tgagctccac accctgcctg gcaatggtat gagagtcgga cctggacagg   6120

gccagctgct gggggagcgg cactggggac tggaggctgg aagcgggtgg tgtgtgtccc   6180

ctgtttactt ttagctgagc tggggttggg tgtacgggtt ctgttcctct gagcctgcgg   6240

cccacctgat gtttacgtgt gtgtgtgagg gggggcgggg gtggcaggtg tccccccctg   6300

gtccccgccc caagagcctg ctgtctgtat ggaggaggtg ctagcccggt ccaccgggct   6360

gctgcccacc cctgcatgcc ccagttgccc accccgcctg cccctggaca tgaagtggtc   6420

acgcttcatc cacggctcct tcccacccct cggcagtggc tgtgcaatgt tttaagttca   6480

caagttcctg ctcctcccca cactgagctc ctttgttcct ccccctccag cctttgcctg   6540

ggaactggtc cttgtttgcc gggcttctcg gagggttcac tgtacattcg ttctcaggtg   6600

gtcttgtggc tgtctttcgg aaaatggtta ttttatatga tttgtcatgg aatttgttct   6660

aataaatcat tcttctatca catggcagca cgctggagcc tgtcaccttg              6710


<210>  8763
<211>  1396
<212>  PRT
<213>  Homo sapiens

<400>  8763

Met Ser Ala Thr Ser Trp Phe Leu Val Ser Ser Ser Gly Ala Arg His 
1               5                   10                  15


Arg Leu Pro Arg Glu Leu Ile Phe Val Gly Arg Glu Glu Cys Glu Leu 
            20                  25                  30


Met Leu Gln Ser Arg Ser Val Asp Lys Gln His Ala Val Ile Asn Tyr 
        35                  40                  45


Asp Gln Asp Arg Asp Glu His Trp Val Lys Asp Leu Gly Ser Leu Asn 
    50                  55                  60


Gly Thr Phe Val Asn Asp Met Arg Ile Pro Asp Gln Lys Tyr Val Thr 
65                  70                  75                  80


Leu Lys Leu Asn Asp Val Ile Arg Phe Gly Tyr Asp Ser Asn Met Tyr 
                85                  90                  95


Val Leu Glu Arg Val Gln His Arg Val Pro Glu Glu Ala Leu Lys His 
            100                 105                 110


Glu Lys Tyr Thr Ser Gln Leu Gln Val Ser Val Lys Gly Leu Ala Pro 
        115                 120                 125


Lys Arg Ser Glu Ala Leu Pro Glu His Thr Pro Tyr Cys Glu Ala Ser 
    130                 135                 140


Asn Pro Arg Pro Glu Lys Gly Asp Arg Arg Pro Gly Thr Glu Ala Ala 
145                 150                 155                 160


Ser Tyr Arg Thr Pro Leu Tyr Gly Gln Pro Ser Trp Trp Gly Glu Asp 
                165                 170                 175


Asp Gly Ser Thr Leu Pro Asp Ala Gln Arg Gln Gly Glu Pro Tyr Pro 
            180                 185                 190


Glu Arg Pro Lys Gly Pro Val Gln Gln Asp Gly Glu Leu His Gly Phe 
        195                 200                 205


Arg Ala Pro Ala Glu Pro Gln Gly Cys Ser Phe Arg Arg Glu Pro Ser 
    210                 215                 220


Tyr Phe Glu Ile Pro Thr Lys Glu Thr Pro Gln Pro Ser Gln Pro Pro 
225                 230                 235                 240


Glu Val Pro Ala His Glu Met Pro Thr Lys Asp Ala Glu Ala Gly Gly 
                245                 250                 255


Gly Gly Ala Ala Pro Val Val Gln Ser His Ala Ser Phe Thr Ile Glu 
            260                 265                 270


Phe Asp Asp Cys Ser Pro Gly Lys Met Lys Ile Lys Asp His Ile Thr 
        275                 280                 285


Lys Phe Ser Leu Arg Gln Arg Arg Pro Pro Gly Lys Glu Ala Thr Pro 
    290                 295                 300


Gly Glu Met Val Ser Ala Glu Thr Lys Val Ala Asp Trp Leu Val Gln 
305                 310                 315                 320


Asn Asp Pro Ser Leu Leu His Arg Val Gly Pro Gly Asp Asp Arg His 
                325                 330                 335


Ser Thr Lys Ser Asp Leu Pro Val His Thr Arg Thr Leu Lys Gly His 
            340                 345                 350


Lys His Glu Asp Gly Thr Gln Ser Asp Ser Glu Asp Pro Leu Ala Lys 
        355                 360                 365


Ala Ala Ser Ala Ala Gly Val Pro Leu Glu Ala Ser Gly Glu Gln Val 
    370                 375                 380


Arg Leu Gln Arg Gln Ile Lys Arg Asp Pro Gln Glu Leu Leu His Asn 
385                 390                 395                 400


Gln Gln Ala Phe Val Ile Glu Phe Phe Asp Glu Asp Thr Pro Arg Lys 
                405                 410                 415


Lys Arg Ser Gln Ser Phe Thr His Ser Pro Ser Gly Asp Pro Lys Ala 
            420                 425                 430


Asp Lys Arg Arg Gly Pro Thr Pro Ala Asp Arg Asp Arg Pro Ser Val 
        435                 440                 445


Pro Ala Pro Val Gln Ala Gly Gly Arg Ser Ser Gly Pro Gln Arg Ala 
    450                 455                 460


Gly Ser Leu Lys Arg Glu Lys Thr Glu Glu Arg Leu Gly Ser Pro Ser 
465                 470                 475                 480


Pro Ala Ser Arg Thr Pro Ala Arg Pro Phe Gly Ser Val Gly Arg Arg 
                485                 490                 495


Ser Arg Leu Ala Gln Asp Phe Met Ala Gln Cys Leu Arg Glu Ser Ser 
            500                 505                 510


Pro Ala Ala Arg Pro Ser Pro Glu Lys Val Pro Pro Val Leu Pro Ala 
        515                 520                 525


Pro Leu Thr Pro His Gly Thr Ser Pro Val Gly Pro Pro Thr Pro Pro 
    530                 535                 540


Pro Ala Pro Thr Asp Pro Gln Leu Thr Lys Ala Arg Lys Gln Glu Glu 
545                 550                 555                 560


Asp Asp Ser Leu Ser Asp Ala Gly Thr Tyr Thr Ile Glu Thr Glu Ala 
                565                 570                 575


Gln Asp Thr Glu Val Glu Glu Ala Arg Lys Met Ile Asp Gln Val Phe 
            580                 585                 590


Gly Val Leu Glu Ser Pro Glu Leu Ser Arg Ala Ser Ser Ala Thr Phe 
        595                 600                 605


Arg Pro Val Ile Arg Gly Asp Arg Asp Glu Ser Asp Asp Gly Gly Val 
    610                 615                 620


Ala Gln Arg Met Ala Leu Leu Gln Glu Phe Ala Ser Arg Pro Leu Gly 
625                 630                 635                 640


Ala Ala Pro Gln Ala Glu His Gln Gly Leu Pro Val Pro Gly Ser Pro 
                645                 650                 655


Gly Gly Gln Lys Trp Val Ser Arg Trp Ala Ser Leu Ala Asp Ser Tyr 
            660                 665                 670


Ser Asp Pro Gly Leu Thr Glu Asp Gly Leu Gly Arg Arg Gly Gly Glu 
        675                 680                 685


Pro Glu Gly Ser Leu Pro Val Arg Met Arg Arg Arg Leu Pro Gln Leu 
    690                 695                 700


Pro Ser Glu Arg Ala Asp Ser Pro Ala Gly Pro Glu Ser Ser Arg Arg 
705                 710                 715                 720


Ser Gly Pro Gly Pro Pro Glu Leu Asp Ser Glu Gln Pro Ser Arg Leu 
                725                 730                 735


Phe Gly Gln Glu Glu Leu Asp Pro Asp Ser Leu Ser Asp Ala Ser Gly 
            740                 745                 750


Ser Asp Gly Gly Arg Gly Pro Glu Pro Gly Val Glu Pro Gln Asp Ser 
        755                 760                 765


Arg Arg Arg Ser Pro Gln Glu Gly Pro Thr Trp Ser Arg Gly Arg Arg 
    770                 775                 780


Ser Pro Arg Ala Pro Gly Glu Pro Thr Pro Ala Ser Phe Phe Ile Gly 
785                 790                 795                 800


Asp Gln Asn Gly Asp Ala Val Leu Ser Arg Lys Pro Leu Ala Ala Pro 
                805                 810                 815


Gly Asp Gly Glu Gly Leu Gly Gln Thr Ala Gln Pro Ser Pro Pro Ala 
            820                 825                 830


Arg Asp Gly Val Tyr Val Ser Ala Asn Gly Arg Met Val Ile Gln Leu 
        835                 840                 845


Arg Pro Gly Arg Ser Pro Glu Pro Asp Gly Pro Ala Pro Ala Phe Leu 
    850                 855                 860


Arg Gln Glu Ser Phe Thr Lys Glu Pro Ala Ser Gly Pro Pro Ala Pro 
865                 870                 875                 880


Gly Lys Pro Pro His Ile Ser Ser His Pro Leu Leu Gln Asp Leu Ala 
                885                 890                 895


Ala Thr Arg Ala Ala Arg Met Asp Phe His Ser Gln Asp Thr His Leu 
            900                 905                 910


Ile Leu Lys Glu Thr Glu Thr Ala Leu Ala Ala Leu Glu Ala Arg Leu 
        915                 920                 925


Leu Ser Asn Ser Val Asp Ala Glu Cys Glu Gly Gly Ser Thr Pro Arg 
    930                 935                 940


Pro Pro Glu Asp Ala Leu Ser Gly Asp Ser Asp Val Asp Thr Ala Ser 
945                 950                 955                 960


Thr Val Ser Leu Arg Ser Gly Lys Ser Gly Pro Ser Pro Thr Thr Pro 
                965                 970                 975


Gln Pro Leu Arg Ala Gln Lys Glu Met Ser Pro Ser Pro Pro Ala Ala 
            980                 985                 990


Gln Asp Pro Gly Gly Thr Ala Leu Val Ser Ala Arg Glu Gln Ser Ser 
        995                 1000                1005


Glu Arg Gln His His Pro Leu Gly Pro Thr Asp Met Gly Arg Gly Glu 
    1010                1015                1020


Pro Val Arg Arg Ser Ala Ile Arg Arg Gly His Arg Pro Arg Gly Ser 
1025                1030                1035                1040


Leu Asp Trp Pro Ser Glu Glu Arg Gly Pro Val Leu Ala His Leu Pro 
                1045                1050                1055


Ser Ser Asp Val Met Ala Ser Asn His Glu Thr Pro Glu Ala Thr Gly 
            1060                1065                1070


Ala Gly Arg Leu Gly Ser Arg Arg Lys Pro Ala Ala Pro Pro Pro Ser 
        1075                1080                1085


Pro Ala Ala Arg Glu Glu Gln Ser Arg Ser Ser Ala Ser Ser Gln Lys 
    1090                1095                1100


Gly Pro Gln Ala Leu Thr Arg Ser Asn Ser Leu Ser Thr Pro Arg Pro 
1105                1110                1115                1120


Thr Arg Ala Ser Arg Leu Arg Arg Ala Arg Leu Gly Asp Ala Ser Asp 
                1125                1130                1135


Thr Glu Ala Ala Asp Gly Glu Arg Gly Ser Leu Gly Asn Pro Glu Pro 
            1140                1145                1150


Val Gly Arg Pro Ala Ala Glu Gln Ala Lys Lys Leu Ser Arg Leu Asp 
        1155                1160                1165


Ile Leu Ala Met Pro Arg Lys Arg Ala Gly Ser Phe Thr Gly Thr Ser 
    1170                1175                1180


Asp Pro Glu Ala Ala Pro Ala Arg Thr Ser Phe Ser Gly Arg Ser Val 
1185                1190                1195                1200


Glu Leu Cys Cys Ala Ser Arg Lys Pro Thr Met Ala Glu Ala Arg Ala 
                1205                1210                1215


Val Ser Arg Lys Ala Ala Asn Thr Ala Thr Thr Thr Gly Pro Arg Gln 
            1220                1225                1230


Pro Phe Ser Arg Ala Arg Ser Gly Ser Ala Arg Tyr Thr Ser Thr Thr 
        1235                1240                1245


Gln Thr Pro Arg Ala Gly Ser Ser Ser Arg Ala Arg Ser Arg Ala Pro 
    1250                1255                1260


Gly Pro Arg Asp Thr Asp Asp Asp Glu Glu Glu Pro Asp Pro Tyr Gly 
1265                1270                1275                1280


Phe Ile Val Gln Thr Ala Glu Ile Ala Glu Ile Ala Arg Leu Ser Gln 
                1285                1290                1295


Thr Leu Val Lys Asp Val Ala Ile Leu Ala Gln Glu Ile His Asp Val 
            1300                1305                1310


Ala Gly Asp Gly Asp Thr Leu Gly Ser Ser Glu Pro Ala His Ser Ala 
        1315                1320                1325


Ser Leu Ser Asn Met Pro Ser Thr Pro Ala Ser Thr Ile Ser Ala Arg 
    1330                1335                1340


Glu Glu Leu Val Gln Arg Ile Pro Glu Ala Ser Leu Asn Phe Gln Lys 
1345                1350                1355                1360


Val Pro Pro Gly Ser Leu Asn Ser Arg Asp Phe Asp Gln Asn Met Asn 
                1365                1370                1375


Asp Ser Cys Glu Asp Ala Leu Ala Asn Lys Thr Arg Pro Arg Asn Arg 
            1380                1385                1390


Glu Glu Ala Arg 
        1395


<210>  8764
<211>  6679
<212>  DNA
<213>  Homo sapiens

<400>  8764
gctcggcccg ggctgccacg agcgtgcggg cctcgccggg catgtcctag gcggcggccc     60

cgcccagcgc tcggccgggc gggcgggcgg gcgcgagggc agggaccgag ccgggccgag    120

ctggggaaca agccggggac caagccgggg accaagccgg ggactaaggc gagccggaga    180

ccgagcccga acagcagtcc cgcagcgtgg acaagcagca tgccgtcatc aactacgacc    240

aggacaggga cgagcactgg gtgaaggacc tgggcagcct caatgggacg tttgtgaatg    300

acatgcgcat cccggaccag aagtacgtca cgctgaagct caacgatgtc atccgcttcg    360

gctacgattc caacatgtat gtgctggagc gtgtgcagca ccgagtcccg gaggaggcac    420

tcaagcatga aaagtacacc agccagctgc aggtgagcgt gaagggtttg gcgcccaaga    480

ggagcgaggc actgccggaa cacacaccat actgcgaggc ctcgaacccc aggccggaga    540

agggggaccg gagaccagga acagaggcag cctcttaccg cacacccctg tatgggcagc    600

cctcctggtg gggtgaggac gatggtagca cgctgcctga cgcccagcgc cagggagagc    660

cctacccaga gcgccccaag ggaccagtgc agcaggacgg ggagctccac ggcttccgcg    720

cccctgctga gcctcagggc tgctcgttcc ggcgggagcc cagctacttc gagatcccca    780

cgaaggagac cccgcagccg tcgcagcccc ccgaggtgcc ggcacacgag atgcccacga    840

aggatgcaga ggcaggtggg ggcggagcgg cccctgtggt gcagagccac gcctccttca    900

ccatcgagtt tgatgactgc agccctggca agatgaagat caaggaccat atcaccaagt    960

tttccctgcg ccagcggcgg cccccgggca aggaggccac acctggcgag atggtgtcgg   1020

ctgagaccaa ggtggccgac tggctggtgc agaatgaccc gagcctgctg caccgggttg   1080

gccctgggga tgaccgccac agcaccaaga gcgacctgcc tgtccacacc cgcaccctga   1140

agggccacaa gcacgaggac ggcacgcaga gtgactcaga ggaccccctg gccaaggcgg   1200

cctcggccgc tggggtgccc ttggaggcca gcggggagca ggtgcggctg cagaggcaga   1260

tcaagcggga cccccaggag ctactacata accagcaggc ctttgtcatc gagttcttcg   1320

acgaggacac accccgaaag aagcgctccc agtccttcac gcacagcccg tccggggacc   1380

ccaaggccga caagcgccgt ggcccaacgc cggccgatag ggaccgcccc agtgtcccag   1440

ccccagtcca ggcagggggc cgcagctcgg ggccacagag ggccggctcg ctcaagcggg   1500

agaagacaga ggaacggctg ggcagcccct cgcccgcctc ccgaacccct gcccgcccct   1560

tcggaagcgt ggggcgccgc tcccgcctgg cccaggactt catggcccag tgtctgcggg   1620

agagctcccc ggccgcccgg cccagccccg agaaggttcc tccggtgctg cccgctcccc   1680

tgacacccca tgggaccagc cccgtgggcc ccccgacccc accgcccgcc cccacggacc   1740

cccagctgac caaggcacgg aaacaggagg aggacgacag cctcagtgac gcagggacat   1800

acaccatcga gaccgaggcg caggacacgg aggtggagga ggcccggaag atgatcgacc   1860

aggtctttgg ggtgttggag tcccctgaac tctccagggc atcttcggcc acctttcgcc   1920

cagtcatcag aggggacaga gatgagtctg atgacggggg cgtggcccag cggatggcgc   1980

tactgcagga gtttgcctcc cggccactgg gtgcggcccc ccaggcggag caccagggcc   2040

tcccggtgcc gggctcccct gggggtcaga agtgggtgtc ccgctgggcc agcctggctg   2100

acagctactc agacccgggc ctcacagagg atggcctggg acgtagaggc ggggagccgg   2160

aggggtccct gcctgtgcgc atgcggcgac ggctccctca gctgcccagt gagagggctg   2220

acagccctgc gggcccagag agcagcagga ggagtgggcc tgggccaccg gagctggaca   2280

gtgagcagcc cagccgcctc ttcggccagg aggagttgga tcctgacagc ctcagcgatg   2340

ccagtgggtc ggacgggggc cgaggccccg agccaggggt ggagccacag gacagcagac   2400

gcaggagccc ccaggagggg cccacgtgga gcaggggtcg gcgctcacca agggcccccg   2460

gggagccaac tcccgcctct ttcttcattg gggaccagaa tggggacgct gtgttatcta   2520

ggaaaccgct tgcggctcca ggggatgggg agggcctagg gcagacagcc cagcccagcc   2580

ccccagcacg ggatggcgtc tatgtcagtg ccaatgggag aatggtcatc cagctacggc   2640

ctggacggtc cccagaaccc gacggccctg ccccagcctt tctccggcaa gagagcttca   2700

ctaaggagcc agccagtggt cccccagcgc ccggcaagcc cccccacatc tccagccacc   2760

cgcttctaca ggacctggcc gctacccggg ccgcacgcat ggacttccac tcccaggaca   2820

cccacctgat cttgaaggag acggagacgg ccctggcggc cctggaggcc cgactcctct   2880

ctaattctgt ggatgccgag tgtgaggggg gcagcacccc gaggccgccg gaggacgccc   2940

tgtctgggga ctcggacgtg gacacagcca gcaccgtcag cctgcgtagt ggcaagagcg   3000

ggcccagccc cacaaccccc cagcctctgc gggcacagaa ggagatgtcg ccatccccgc   3060

cagctgcaca ggacccggga ggcaccgccc tggtcagtgc ccgtgagcag tcctcagaga   3120

ggcagcatca cccacttggc ccgacggaca tgggccgtgg agagccggta cggcgctcag   3180

ccataaggcg tggccacagg ccccgagggt ccctggattg gcccagtgag gagcgtggcc   3240

ctgtcctcgc ccacctaccc agctcagatg tgatggcctc caaccacgaa acccctgagg   3300

ccaccggggc aggacggcta ggttctcgcc ggaaaccagc ggccccaccg ccatccccag   3360

ctgcccggga ggagcagagc cgtagctcag ccagctccca gaaggggccg caggccttga   3420

cccgctccaa cagcctgtcc acccctcgcc ccacacgggc ctcccggctg aggcgggccc   3480

ggctggggga cgcttcagac actgaggctg cggatggtga gcgggggtcc ctgggcaacc   3540

ctgagcccgt gggccggcca gctgctgagc aggccaagaa gctgtcacgc ctggacatcc   3600

tggccatgcc ccggaagcgg gccggctcct tcacagggac tagtgacccc gaggcagccc   3660

ctgcccgcac cagcttctct ggccgcagtg tggagttgtg ctgtgccagc cgcaagccca   3720

ccatggccga agcacgggct gtctccagga aggctgccaa cacagccacc accacgggtc   3780

cccgccagcc cttcagcagg gcccgctcag gcagtgcccg atacacctcc aacacgaggc   3840

gccggcagca gggctcggat tacacgtcca cctctgagga ggagtacggc tcccgccacg   3900

gctcccccaa acacacacgc tcccacacct caacagccac tcagaccccg agggctggca   3960

gctccagccg ggctcgttcc cgggcccccg gcccccggga cacggacgac gatgaggagg   4020

agcctgaccc ttatggtttc atcgtgcaga cggcagagat tgcggagatt gccaggctga   4080

gccagacgct ggtgaaggac gtggccatcc tagcccagga gatccacgat gtggctgggg   4140

acggtgacac actgggctcc tcggagcctg cccacagcgc ctccctcagc aacatgccca   4200

gcacccccgc ctcgaccatc tctgcccggg aggagctggt gcagcgcatc cccgaggcca   4260

gcctcaactt ccagaaggtg ccgcccggct cgctgaactc tcgggacttt gaccagaaca   4320

tgaacgacag ctgtgaggac gccctggcca acaagacgcg gcctcggaac cgagaggagg   4380

cacggtgatc ttcgataacc tgatgctgaa cccggtgtcc cagctgtcgc aggccatccg   4440

tgagaacaca gagcaccttg ccgagaagat gaagatcctc tttcagaaca cagggagagc   4500

ttgggaggac ctggaagcca ggatcaacgc cgagaacgag gtgcccatcc tgaagacatc   4560

taacaaggaa atcagctcca tcctgaagga actgaggcgg gtgcagaaac agctggaagt   4620

tatcaatgcc atcgtggacc ccagtgggag cctggacctg ctcacaggaa acaggagctt   4680

ggccagctct gcacagccgg ggctggggaa gggccgcgtg gctgcccaga gcccaccctc   4740

acccgcctca gccgaggccc tgctgccagc cctgcccctg aggaatttcc cacagcgggc   4800

cagctgtggg cctcccagcc tcccggaccc caccttcctc cctgatgccg agaggttcct   4860

gatctaggcc ccagacctgg ccaggccagc ctccctgtgc gtgtgcgtct ctgccttccg   4920

tccgccgcac acccgcctgc ctggccgcag gtggttctcc ctgaagaccc ccacatgtgc   4980

catatccctg tgggcgggtg cctcccacgc ccttgccccc tcgtcagctc ccagccagca   5040

ccctactcac cctgtccagc cccatggcca cccccacccc tgcctcgccc cctacaggcc   5100

tctgggccca gctcctggcc aggctgctgc caaggtcaag ccctcaaggg cattaccccg   5160

cctcctcttc atcactgtta tttttgtctt tagctttaaa ggaaagagtt gttggtgcca   5220

ttgcaggtgc cccctccagg cctgactggc tccgccaggc actaacctgc cataaccctt   5280

tgtgctggcc tgcggccagg cagaggaaga gaggtcgact gtggggtcat ttggtgccaa   5340

acatggaggt gggcaggctc acctgttcct gggactgtct gagatggcag ggcacttgcc   5400

ctggtggctc ccacctgacc ccaggccttt tataggcagg agccccactg cttccagcct   5460

ctggtgccaa cacagttgcc aaacccattg agcttggggc tgccctgtgg aggcctcctg   5520

ggtatggacc aggggcttgt tgagagctga gccatgcaca caggtgcaga caccccccaa   5580

ctcccatgca cacggctagt ccaggcgcct ccacgctgca ccgtgaggac tgcagggcat   5640

gtccccgtga ggggctatgg gcctctgtag gtgggcttcc aaggtcctgg gtgcagccgg   5700

gtgcatggca gcccttctgg cgggggtgag cgcacgacca aagtcactgg aagccgggtt   5760

tccggaagct cgcagcttgg cctgcaccac acgccctccc cttttggctt cacgccatca   5820

ggcctcaagt gggcatgggg gcagggacgg gcccaggaac tgttgttttc tcaggattct   5880

ttcagctggg aacatggcag gtgagcagag cttggtgcct ctgccgtggc ccctgctggg   5940

gcagcccgtg ttgccggagc ctctaagcca aagagcccgt tggccgtggt tggtgggggt   6000

ggacgtgggg gtgtcccacc tggaccagac tggcgtgggt gagctccaca ccctgcctgg   6060

caatggtatg agagtcggac ctggacaggg ccagctgctg ggggagcggc actggggact   6120

ggaggctgga agcgggtggt gtgtgtcccc tgtttacttt tagctgagct ggggttgggt   6180

gtacgggttc tgttcctctg agcctgcggc ccacctgatg tttacgtgtg tgtgtgaggg   6240

ggggcggggg tggcaggtgt ccccccctgg tccccgcccc aagagcctgc tgtctgtatg   6300

gaggaggtgc tagcccggtc caccgggctg ctgcccaccc ctgcatgccc cagttgccca   6360

ccccgcctgc ccctggacat gaagtggtca cgcttcatcc acggctcctt cccacccctc   6420

ggcagtggct gtgcaatgtt ttaagttcac aagttcctgc tcctccccac actgagctcc   6480

tttgttcctc cccctccagc ctttgcctgg gaactggtcc ttgtttgccg ggcttctcgg   6540

agggttcact gtacattcgt tctcaggtgg tcttgtggct gtctttcgga aaatggttat   6600

tttatatgat ttgtcatgga atttgttcta ataaatcatt cttctatcac atggcagcac   6660

gctggagcct gtcaccttg                                                6679


<210>  8765
<211>  1361
<212>  PRT
<213>  Homo sapiens

<400>  8765

Met Arg Ile Pro Asp Gln Lys Tyr Val Thr Leu Lys Leu Asn Asp Val 
1               5                   10                  15


Ile Arg Phe Gly Tyr Asp Ser Asn Met Tyr Val Leu Glu Arg Val Gln 
            20                  25                  30


His Arg Val Pro Glu Glu Ala Leu Lys His Glu Lys Tyr Thr Ser Gln 
        35                  40                  45


Leu Gln Val Ser Val Lys Gly Leu Ala Pro Lys Arg Ser Glu Ala Leu 
    50                  55                  60


Pro Glu His Thr Pro Tyr Cys Glu Ala Ser Asn Pro Arg Pro Glu Lys 
65                  70                  75                  80


Gly Asp Arg Arg Pro Gly Thr Glu Ala Ala Ser Tyr Arg Thr Pro Leu 
                85                  90                  95


Tyr Gly Gln Pro Ser Trp Trp Gly Glu Asp Asp Gly Ser Thr Leu Pro 
            100                 105                 110


Asp Ala Gln Arg Gln Gly Glu Pro Tyr Pro Glu Arg Pro Lys Gly Pro 
        115                 120                 125


Val Gln Gln Asp Gly Glu Leu His Gly Phe Arg Ala Pro Ala Glu Pro 
    130                 135                 140


Gln Gly Cys Ser Phe Arg Arg Glu Pro Ser Tyr Phe Glu Ile Pro Thr 
145                 150                 155                 160


Lys Glu Thr Pro Gln Pro Ser Gln Pro Pro Glu Val Pro Ala His Glu 
                165                 170                 175


Met Pro Thr Lys Asp Ala Glu Ala Gly Gly Gly Gly Ala Ala Pro Val 
            180                 185                 190


Val Gln Ser His Ala Ser Phe Thr Ile Glu Phe Asp Asp Cys Ser Pro 
        195                 200                 205


Gly Lys Met Lys Ile Lys Asp His Ile Thr Lys Phe Ser Leu Arg Gln 
    210                 215                 220


Arg Arg Pro Pro Gly Lys Glu Ala Thr Pro Gly Glu Met Val Ser Ala 
225                 230                 235                 240


Glu Thr Lys Val Ala Asp Trp Leu Val Gln Asn Asp Pro Ser Leu Leu 
                245                 250                 255


His Arg Val Gly Pro Gly Asp Asp Arg His Ser Thr Lys Ser Asp Leu 
            260                 265                 270


Pro Val His Thr Arg Thr Leu Lys Gly His Lys His Glu Asp Gly Thr 
        275                 280                 285


Gln Ser Asp Ser Glu Asp Pro Leu Ala Lys Ala Ala Ser Ala Ala Gly 
    290                 295                 300


Val Pro Leu Glu Ala Ser Gly Glu Gln Val Arg Leu Gln Arg Gln Ile 
305                 310                 315                 320


Lys Arg Asp Pro Gln Glu Leu Leu His Asn Gln Gln Ala Phe Val Ile 
                325                 330                 335


Glu Phe Phe Asp Glu Asp Thr Pro Arg Lys Lys Arg Ser Gln Ser Phe 
            340                 345                 350


Thr His Ser Pro Ser Gly Asp Pro Lys Ala Asp Lys Arg Arg Gly Pro 
        355                 360                 365


Thr Pro Ala Asp Arg Asp Arg Pro Ser Val Pro Ala Pro Val Gln Ala 
    370                 375                 380


Gly Gly Arg Ser Ser Gly Pro Gln Arg Ala Gly Ser Leu Lys Arg Glu 
385                 390                 395                 400


Lys Thr Glu Glu Arg Leu Gly Ser Pro Ser Pro Ala Ser Arg Thr Pro 
                405                 410                 415


Ala Arg Pro Phe Gly Ser Val Gly Arg Arg Ser Arg Leu Ala Gln Asp 
            420                 425                 430


Phe Met Ala Gln Cys Leu Arg Glu Ser Ser Pro Ala Ala Arg Pro Ser 
        435                 440                 445


Pro Glu Lys Val Pro Pro Val Leu Pro Ala Pro Leu Thr Pro His Gly 
    450                 455                 460


Thr Ser Pro Val Gly Pro Pro Thr Pro Pro Pro Ala Pro Thr Asp Pro 
465                 470                 475                 480


Gln Leu Thr Lys Ala Arg Lys Gln Glu Glu Asp Asp Ser Leu Ser Asp 
                485                 490                 495


Ala Gly Thr Tyr Thr Ile Glu Thr Glu Ala Gln Asp Thr Glu Val Glu 
            500                 505                 510


Glu Ala Arg Lys Met Ile Asp Gln Val Phe Gly Val Leu Glu Ser Pro 
        515                 520                 525


Glu Leu Ser Arg Ala Ser Ser Ala Thr Phe Arg Pro Val Ile Arg Gly 
    530                 535                 540


Asp Arg Asp Glu Ser Asp Asp Gly Gly Val Ala Gln Arg Met Ala Leu 
545                 550                 555                 560


Leu Gln Glu Phe Ala Ser Arg Pro Leu Gly Ala Ala Pro Gln Ala Glu 
                565                 570                 575


His Gln Gly Leu Pro Val Pro Gly Ser Pro Gly Gly Gln Lys Trp Val 
            580                 585                 590


Ser Arg Trp Ala Ser Leu Ala Asp Ser Tyr Ser Asp Pro Gly Leu Thr 
        595                 600                 605


Glu Asp Gly Leu Gly Arg Arg Gly Gly Glu Pro Glu Gly Ser Leu Pro 
    610                 615                 620


Val Arg Met Arg Arg Arg Leu Pro Gln Leu Pro Ser Glu Arg Ala Asp 
625                 630                 635                 640


Ser Pro Ala Gly Pro Glu Ser Ser Arg Arg Ser Gly Pro Gly Pro Pro 
                645                 650                 655


Glu Leu Asp Ser Glu Gln Pro Ser Arg Leu Phe Gly Gln Glu Glu Leu 
            660                 665                 670


Asp Pro Asp Ser Leu Ser Asp Ala Ser Gly Ser Asp Gly Gly Arg Gly 
        675                 680                 685


Pro Glu Pro Gly Val Glu Pro Gln Asp Ser Arg Arg Arg Ser Pro Gln 
    690                 695                 700


Glu Gly Pro Thr Trp Ser Arg Gly Arg Arg Ser Pro Arg Ala Pro Gly 
705                 710                 715                 720


Glu Pro Thr Pro Ala Ser Phe Phe Ile Gly Asp Gln Asn Gly Asp Ala 
                725                 730                 735


Val Leu Ser Arg Lys Pro Leu Ala Ala Pro Gly Asp Gly Glu Gly Leu 
            740                 745                 750


Gly Gln Thr Ala Gln Pro Ser Pro Pro Ala Arg Asp Gly Val Tyr Val 
        755                 760                 765


Ser Ala Asn Gly Arg Met Val Ile Gln Leu Arg Pro Gly Arg Ser Pro 
    770                 775                 780


Glu Pro Asp Gly Pro Ala Pro Ala Phe Leu Arg Gln Glu Ser Phe Thr 
785                 790                 795                 800


Lys Glu Pro Ala Ser Gly Pro Pro Ala Pro Gly Lys Pro Pro His Ile 
                805                 810                 815


Ser Ser His Pro Leu Leu Gln Asp Leu Ala Ala Thr Arg Ala Ala Arg 
            820                 825                 830


Met Asp Phe His Ser Gln Asp Thr His Leu Ile Leu Lys Glu Thr Glu 
        835                 840                 845


Thr Ala Leu Ala Ala Leu Glu Ala Arg Leu Leu Ser Asn Ser Val Asp 
    850                 855                 860


Ala Glu Cys Glu Gly Gly Ser Thr Pro Arg Pro Pro Glu Asp Ala Leu 
865                 870                 875                 880


Ser Gly Asp Ser Asp Val Asp Thr Ala Ser Thr Val Ser Leu Arg Ser 
                885                 890                 895


Gly Lys Ser Gly Pro Ser Pro Thr Thr Pro Gln Pro Leu Arg Ala Gln 
            900                 905                 910


Lys Glu Met Ser Pro Ser Pro Pro Ala Ala Gln Asp Pro Gly Gly Thr 
        915                 920                 925


Ala Leu Val Ser Ala Arg Glu Gln Ser Ser Glu Arg Gln His His Pro 
    930                 935                 940


Leu Gly Pro Thr Asp Met Gly Arg Gly Glu Pro Val Arg Arg Ser Ala 
945                 950                 955                 960


Ile Arg Arg Gly His Arg Pro Arg Gly Ser Leu Asp Trp Pro Ser Glu 
                965                 970                 975


Glu Arg Gly Pro Val Leu Ala His Leu Pro Ser Ser Asp Val Met Ala 
            980                 985                 990


Ser Asn His Glu Thr Pro Glu Ala Thr Gly Ala Gly Arg Leu Gly Ser 
        995                 1000                1005


Arg Arg Lys Pro Ala Ala Pro Pro Pro Ser Pro Ala Ala Arg Glu Glu 
    1010                1015                1020


Gln Ser Arg Ser Ser Ala Ser Ser Gln Lys Gly Pro Gln Ala Leu Thr 
1025                1030                1035                1040


Arg Ser Asn Ser Leu Ser Thr Pro Arg Pro Thr Arg Ala Ser Arg Leu 
                1045                1050                1055


Arg Arg Ala Arg Leu Gly Asp Ala Ser Asp Thr Glu Ala Ala Asp Gly 
            1060                1065                1070


Glu Arg Gly Ser Leu Gly Asn Pro Glu Pro Val Gly Arg Pro Ala Ala 
        1075                1080                1085


Glu Gln Ala Lys Lys Leu Ser Arg Leu Asp Ile Leu Ala Met Pro Arg 
    1090                1095                1100


Lys Arg Ala Gly Ser Phe Thr Gly Thr Ser Asp Pro Glu Ala Ala Pro 
1105                1110                1115                1120


Ala Arg Thr Ser Phe Ser Gly Arg Ser Val Glu Leu Cys Cys Ala Ser 
                1125                1130                1135


Arg Lys Pro Thr Met Ala Glu Ala Arg Ala Val Ser Arg Lys Ala Ala 
            1140                1145                1150


Asn Thr Ala Thr Thr Thr Gly Pro Arg Gln Pro Phe Ser Arg Ala Arg 
        1155                1160                1165


Ser Gly Ser Ala Arg Tyr Thr Ser Asn Thr Arg Arg Arg Gln Gln Gly 
    1170                1175                1180


Ser Asp Tyr Thr Ser Thr Ser Glu Glu Glu Tyr Gly Ser Arg His Gly 
1185                1190                1195                1200


Ser Pro Lys His Thr Arg Ser His Thr Ser Thr Ala Thr Gln Thr Pro 
                1205                1210                1215


Arg Ala Gly Ser Ser Ser Arg Ala Arg Ser Arg Ala Pro Gly Pro Arg 
            1220                1225                1230


Asp Thr Asp Asp Asp Glu Glu Glu Pro Asp Pro Tyr Gly Phe Ile Val 
        1235                1240                1245


Gln Thr Ala Glu Ile Ala Glu Ile Ala Arg Leu Ser Gln Thr Leu Val 
    1250                1255                1260


Lys Asp Val Ala Ile Leu Ala Gln Glu Ile His Asp Val Ala Gly Asp 
1265                1270                1275                1280


Gly Asp Thr Leu Gly Ser Ser Glu Pro Ala His Ser Ala Ser Leu Ser 
                1285                1290                1295


Asn Met Pro Ser Thr Pro Ala Ser Thr Ile Ser Ala Arg Glu Glu Leu 
            1300                1305                1310


Val Gln Arg Ile Pro Glu Ala Ser Leu Asn Phe Gln Lys Val Pro Pro 
        1315                1320                1325


Gly Ser Leu Asn Ser Arg Asp Phe Asp Gln Asn Met Asn Asp Ser Cys 
    1330                1335                1340


Glu Asp Ala Leu Ala Asn Lys Thr Arg Pro Arg Asn Arg Glu Glu Ala 
1345                1350                1355                1360


Arg 



<210>  8766
<211>  6574
<212>  DNA
<213>  Homo sapiens

<400>  8766
gctcggcccg ggctgccacg agcgtgcggg cctcgccggg catgtcctag gcggcggccc     60

cgcccagcgc tcggccgggc gggcgggcgg gcgcgagggc agggaccgag ccgggccgag    120

ctggggaaca agccggggac caagccgggg accaagccgg ggactaaggc gagccggaga    180

ccgagcccga acagcagtcc cgcagcgtgg acaagcagca tgccgtcatc aactacgacc    240

aggacaggga cgagcactgg gtgaaggacc tgggcagcct caatgggacg tttgtgaatg    300

acatgcgcat cccggaccag aagtacgtca cgctgaagct caacgatgtc atccgcttcg    360

gctacgattc caacatgtat gtgctggagc gtgtgcagca ccgagtcccg gaggaggcac    420

tcaagcatga aaagtacacc agccagctgc aggtgagcgt gaagggtttg gcgcccaaga    480

ggagcgaggc actgccggaa cacacaccat actgcgaggc ctcgaacccc aggccggaga    540

agggggaccg gagaccagga acagaggcag cctcttaccg cacacccctg tatgggcagc    600

cctcctggtg gggtgaggac gatggtagca cgctgcctga cgcccagcgc cagggagagc    660

cctacccaga gcgccccaag ggaccagtgc agcaggacgg ggagctccac ggcttccgcg    720

cccctgctga gcctcagggc tgctcgttcc ggcgggagcc cagctacttc gagatcccca    780

cgaaggagac cccgcagccg tcgcagcccc ccgaggtgcc ggcacacgag atgcccacga    840

aggatgcaga ggcaggtggg ggcggagcgg cccctgtggt gcagagccac gcctccttca    900

ccatcgagtt tgatgactgc agccctggca agatgaagat caaggaccat atcaccaagt    960

tttccctgcg ccagcggcgg cccccgggca aggaggccac acctggcgag atggtgtcgg   1020

ctgagaccaa ggtggccgac tggctggtgc agaatgaccc gagcctgctg caccgggttg   1080

gccctgggga tgaccgccac agcaccaaga gcgacctgcc tgtccacacc cgcaccctga   1140

agggccacaa gcacgaggac ggcacgcaga gtgactcaga ggaccccctg gccaaggcgg   1200

cctcggccgc tggggtgccc ttggaggcca gcggggagca ggtgcggctg cagaggcaga   1260

tcaagcggga cccccaggag ctactacata accagcaggc ctttgtcatc gagttcttcg   1320

acgaggacac accccgaaag aagcgctccc agtccttcac gcacagcccg tccggggacc   1380

ccaaggccga caagcgccgt ggcccaacgc cggccgatag ggaccgcccc agtgtcccag   1440

ccccagtcca ggcagggggc cgcagctcgg ggccacagag ggccggctcg ctcaagcggg   1500

agaagacaga ggaacggctg ggcagcccct cgcccgcctc ccgaacccct gcccgcccct   1560

tcggaagcgt ggggcgccgc tcccgcctgg cccaggactt catggcccag tgtctgcggg   1620

agagctcccc ggccgcccgg cccagccccg agaaggttcc tccggtgctg cccgctcccc   1680

tgacacccca tgggaccagc cccgtgggcc ccccgacccc accgcccgcc cccacggacc   1740

cccagctgac caaggcacgg aaacaggagg aggacgacag cctcagtgac gcagggacat   1800

acaccatcga gaccgaggcg caggacacgg aggtggagga ggcccggaag atgatcgacc   1860

aggtctttgg ggtgttggag tcccctgaac tctccagggc atcttcggcc acctttcgcc   1920

cagtcatcag aggggacaga gatgagtctg atgacggggg cgtggcccag cggatggcgc   1980

tactgcagga gtttgcctcc cggccactgg gtgcggcccc ccaggcggag caccagggcc   2040

tcccggtgcc gggctcccct gggggtcaga agtgggtgtc ccgctgggcc agcctggctg   2100

acagctactc agacccgggc ctcacagagg atggcctggg acgtagaggc ggggagccgg   2160

aggggtccct gcctgtgcgc atgcggcgac ggctccctca gctgcccagt gagagggctg   2220

acagccctgc gggcccagag agcagcagga ggagtgggcc tgggccaccg gagctggaca   2280

gtgagcagcc cagccgcctc ttcggccagg aggagttgga tcctgacagc ctcagcgatg   2340

ccagtgggtc ggacgggggc cgaggccccg agccaggggt ggagccacag gacagcagac   2400

gcaggagccc ccaggagggg cccacgtgga gcaggggtcg gcgctcacca agggcccccg   2460

gggagccaac tcccgcctct ttcttcattg gggaccagaa tggggacgct gtgttatcta   2520

ggaaaccgct tgcggctcca ggggatgggg agggcctagg gcagacagcc cagcccagcc   2580

ccccagcacg ggatggcgtc tatgtcagtg ccaatgggag aatggtcatc cagctacggc   2640

ctggacggtc cccagaaccc gacggccctg ccccagcctt tctccggcaa gagagcttca   2700

ctaaggagcc agccagtggt cccccagcgc ccggcaagcc cccccacatc tccagccacc   2760

cgcttctaca ggacctggcc gctacccggg ccgcacgcat ggacttccac tcccaggaca   2820

cccacctgat cttgaaggag acggagacgg ccctggcggc cctggaggcc cgactcctct   2880

ctaattctgt ggatgccgag tgtgaggggg gcagcacccc gaggccgccg gaggacgccc   2940

tgtctgggga ctcggacgtg gacacagcca gcaccgtcag cctgcgtagt ggcaagagcg   3000

ggcccagccc cacaaccccc cagcctctgc gggcacagaa ggagatgtcg ccatccccgc   3060

cagctgcaca ggacccggga ggcaccgccc tggtcagtgc ccgtgagcag tcctcagaga   3120

ggcagcatca cccacttggc ccgacggaca tgggccgtgg agagccggta cggcgctcag   3180

ccataaggcg tggccacagg ccccgagggt ccctggattg gcccagtgag gagcgtggcc   3240

ctgtcctcgc ccacctaccc agctcagatg tgatggcctc caaccacgaa acccctgagg   3300

ccaccggggc aggacggcta ggttctcgcc ggaaaccagc ggccccaccg ccatccccag   3360

ctgcccggga ggagcagagc cgtagctcag ccagctccca gaaggggccg caggccttga   3420

cccgctccaa cagcctgtcc acccctcgcc ccacacgggc ctcccggctg aggcgggccc   3480

ggctggggga cgcttcagac actgaggctg cggatggtga gcgggggtcc ctgggcaacc   3540

ctgagcccgt gggccggcca gctgctgagc aggccaagaa gctgtcacgc ctggacatcc   3600

tggccatgcc ccggaagcgg gccggctcct tcacagggac tagtgacccc gaggcagccc   3660

ctgcccgcac cagcttctct ggccgcagtg tggagttgtg ctgtgccagc cgcaagccca   3720

ccatggccga agcacgggct gtctccagga aggctgccaa cacagccacc accacgggtc   3780

cccgccagcc cttcagcagg gcccgctcag gcagtgcccg atacacctcc accactcaga   3840

ccccgagggc tggcagctcc agccgggctc gttcccgggc ccccggcccc cgggacacgg   3900

acgacgatga ggaggagcct gacccttatg gtttcatcgt gcagacggca gagattgcgg   3960

agattgccag gctgagccag acgctggtga aggacgtggc catcctagcc caggagatcc   4020

acgatgtggc tggggacggt gacacactgg gctcctcgga gcctgcccac agcgcctccc   4080

tcagcaacat gcccagcacc cccgcctcga ccatctctgc ccgggaggag ctggtgcagc   4140

gcatccccga ggccagcctc aacttccaga aggtgccgcc cggctcgctg aactctcggg   4200

actttgacca gaacatgaac gacagctgtg aggacgccct ggccaacaag acgcggcctc   4260

ggaaccgaga ggaggcacgg tgatcttcga taacctgatg ctgaacccgg tgtcccagct   4320

gtcgcaggcc atccgtgaga acacagagca ccttgccgag aagatgaaga tcctctttca   4380

gaacacaggg agagcttggg aggacctgga agccaggatc aacgccgaga acgaggtgcc   4440

catcctgaag acatctaaca aggaaatcag ctccatcctg aaggaactga ggcgggtgca   4500

gaaacagctg gaagttatca atgccatcgt ggaccccagt gggagcctgg acctgctcac   4560

aggaaacagg agcttggcca gctctgcaca gccggggctg gggaagggcc gcgtggctgc   4620

ccagagccca ccctcacccg cctcagccga ggccctgctg ccagccctgc ccctgaggaa   4680

tttcccacag cgggccagct gtgggcctcc cagcctcccg gaccccacct tcctccctga   4740

tgccgagagg ttcctgatct aggccccaga cctggccagg ccagcctccc tgtgcgtgtg   4800

cgtctctgcc ttccgtccgc cgcacacccg cctgcctggc cgcaggtggt tctccctgaa   4860

gacccccaca tgtgccatat ccctgtgggc gggtgcctcc cacgcccttg ccccctcgtc   4920

agctcccagc cagcacccta ctcaccctgt ccagccccat ggccaccccc acccctgcct   4980

cgccccctac aggcctctgg gcccagctcc tggccaggct gctgccaagg tcaagccctc   5040

aagggcatta ccccgcctcc tcttcatcac tgttattttt gtctttagct ttaaaggaaa   5100

gagttgttgg tgccattgca ggtgccccct ccaggcctga ctggctccgc caggcactaa   5160

cctgccataa ccctttgtgc tggcctgcgg ccaggcagag gaagagaggt cgactgtggg   5220

gtcatttggt gccaaacatg gaggtgggca ggctcacctg ttcctgggac tgtctgagat   5280

ggcagggcac ttgccctggt ggctcccacc tgaccccagg ccttttatag gcaggagccc   5340

cactgcttcc agcctctggt gccaacacag ttgccaaacc cattgagctt ggggctgccc   5400

tgtggaggcc tcctgggtat ggaccagggg cttgttgaga gctgagccat gcacacaggt   5460

gcagacaccc cccaactccc atgcacacgg ctagtccagg cgcctccacg ctgcaccgtg   5520

aggactgcag ggcatgtccc cgtgaggggc tatgggcctc tgtaggtggg cttccaaggt   5580

cctgggtgca gccgggtgca tggcagccct tctggcgggg gtgagcgcac gaccaaagtc   5640

actggaagcc gggtttccgg aagctcgcag cttggcctgc accacacgcc ctcccctttt   5700

ggcttcacgc catcaggcct caagtgggca tgggggcagg gacgggccca ggaactgttg   5760

ttttctcagg attctttcag ctgggaacat ggcaggtgag cagagcttgg tgcctctgcc   5820

gtggcccctg ctggggcagc ccgtgttgcc ggagcctcta agccaaagag cccgttggcc   5880

gtggttggtg ggggtggacg tgggggtgtc ccacctggac cagactggcg tgggtgagct   5940

ccacaccctg cctggcaatg gtatgagagt cggacctgga cagggccagc tgctggggga   6000

gcggcactgg ggactggagg ctggaagcgg gtggtgtgtg tcccctgttt acttttagct   6060

gagctggggt tgggtgtacg ggttctgttc ctctgagcct gcggcccacc tgatgtttac   6120

gtgtgtgtgt gagggggggc gggggtggca ggtgtccccc cctggtcccc gccccaagag   6180

cctgctgtct gtatggagga ggtgctagcc cggtccaccg ggctgctgcc cacccctgca   6240

tgccccagtt gcccaccccg cctgcccctg gacatgaagt ggtcacgctt catccacggc   6300

tccttcccac ccctcggcag tggctgtgca atgttttaag ttcacaagtt cctgctcctc   6360

cccacactga gctcctttgt tcctccccct ccagcctttg cctgggaact ggtccttgtt   6420

tgccgggctt ctcggagggt tcactgtaca ttcgttctca ggtggtcttg tggctgtctt   6480

tcggaaaatg gttattttat atgatttgtc atggaatttg ttctaataaa tcattcttct   6540

atcacatggc agcacgctgg agcctgtcac cttg                               6574


<210>  8767
<211>  1326
<212>  PRT
<213>  Homo sapiens

<400>  8767

Met Arg Ile Pro Asp Gln Lys Tyr Val Thr Leu Lys Leu Asn Asp Val 
1               5                   10                  15


Ile Arg Phe Gly Tyr Asp Ser Asn Met Tyr Val Leu Glu Arg Val Gln 
            20                  25                  30


His Arg Val Pro Glu Glu Ala Leu Lys His Glu Lys Tyr Thr Ser Gln 
        35                  40                  45


Leu Gln Val Ser Val Lys Gly Leu Ala Pro Lys Arg Ser Glu Ala Leu 
    50                  55                  60


Pro Glu His Thr Pro Tyr Cys Glu Ala Ser Asn Pro Arg Pro Glu Lys 
65                  70                  75                  80


Gly Asp Arg Arg Pro Gly Thr Glu Ala Ala Ser Tyr Arg Thr Pro Leu 
                85                  90                  95


Tyr Gly Gln Pro Ser Trp Trp Gly Glu Asp Asp Gly Ser Thr Leu Pro 
            100                 105                 110


Asp Ala Gln Arg Gln Gly Glu Pro Tyr Pro Glu Arg Pro Lys Gly Pro 
        115                 120                 125


Val Gln Gln Asp Gly Glu Leu His Gly Phe Arg Ala Pro Ala Glu Pro 
    130                 135                 140


Gln Gly Cys Ser Phe Arg Arg Glu Pro Ser Tyr Phe Glu Ile Pro Thr 
145                 150                 155                 160


Lys Glu Thr Pro Gln Pro Ser Gln Pro Pro Glu Val Pro Ala His Glu 
                165                 170                 175


Met Pro Thr Lys Asp Ala Glu Ala Gly Gly Gly Gly Ala Ala Pro Val 
            180                 185                 190


Val Gln Ser His Ala Ser Phe Thr Ile Glu Phe Asp Asp Cys Ser Pro 
        195                 200                 205


Gly Lys Met Lys Ile Lys Asp His Ile Thr Lys Phe Ser Leu Arg Gln 
    210                 215                 220


Arg Arg Pro Pro Gly Lys Glu Ala Thr Pro Gly Glu Met Val Ser Ala 
225                 230                 235                 240


Glu Thr Lys Val Ala Asp Trp Leu Val Gln Asn Asp Pro Ser Leu Leu 
                245                 250                 255


His Arg Val Gly Pro Gly Asp Asp Arg His Ser Thr Lys Ser Asp Leu 
            260                 265                 270


Pro Val His Thr Arg Thr Leu Lys Gly His Lys His Glu Asp Gly Thr 
        275                 280                 285


Gln Ser Asp Ser Glu Asp Pro Leu Ala Lys Ala Ala Ser Ala Ala Gly 
    290                 295                 300


Val Pro Leu Glu Ala Ser Gly Glu Gln Val Arg Leu Gln Arg Gln Ile 
305                 310                 315                 320


Lys Arg Asp Pro Gln Glu Leu Leu His Asn Gln Gln Ala Phe Val Ile 
                325                 330                 335


Glu Phe Phe Asp Glu Asp Thr Pro Arg Lys Lys Arg Ser Gln Ser Phe 
            340                 345                 350


Thr His Ser Pro Ser Gly Asp Pro Lys Ala Asp Lys Arg Arg Gly Pro 
        355                 360                 365


Thr Pro Ala Asp Arg Asp Arg Pro Ser Val Pro Ala Pro Val Gln Ala 
    370                 375                 380


Gly Gly Arg Ser Ser Gly Pro Gln Arg Ala Gly Ser Leu Lys Arg Glu 
385                 390                 395                 400


Lys Thr Glu Glu Arg Leu Gly Ser Pro Ser Pro Ala Ser Arg Thr Pro 
                405                 410                 415


Ala Arg Pro Phe Gly Ser Val Gly Arg Arg Ser Arg Leu Ala Gln Asp 
            420                 425                 430


Phe Met Ala Gln Cys Leu Arg Glu Ser Ser Pro Ala Ala Arg Pro Ser 
        435                 440                 445


Pro Glu Lys Val Pro Pro Val Leu Pro Ala Pro Leu Thr Pro His Gly 
    450                 455                 460


Thr Ser Pro Val Gly Pro Pro Thr Pro Pro Pro Ala Pro Thr Asp Pro 
465                 470                 475                 480


Gln Leu Thr Lys Ala Arg Lys Gln Glu Glu Asp Asp Ser Leu Ser Asp 
                485                 490                 495


Ala Gly Thr Tyr Thr Ile Glu Thr Glu Ala Gln Asp Thr Glu Val Glu 
            500                 505                 510


Glu Ala Arg Lys Met Ile Asp Gln Val Phe Gly Val Leu Glu Ser Pro 
        515                 520                 525


Glu Leu Ser Arg Ala Ser Ser Ala Thr Phe Arg Pro Val Ile Arg Gly 
    530                 535                 540


Asp Arg Asp Glu Ser Asp Asp Gly Gly Val Ala Gln Arg Met Ala Leu 
545                 550                 555                 560


Leu Gln Glu Phe Ala Ser Arg Pro Leu Gly Ala Ala Pro Gln Ala Glu 
                565                 570                 575


His Gln Gly Leu Pro Val Pro Gly Ser Pro Gly Gly Gln Lys Trp Val 
            580                 585                 590


Ser Arg Trp Ala Ser Leu Ala Asp Ser Tyr Ser Asp Pro Gly Leu Thr 
        595                 600                 605


Glu Asp Gly Leu Gly Arg Arg Gly Gly Glu Pro Glu Gly Ser Leu Pro 
    610                 615                 620


Val Arg Met Arg Arg Arg Leu Pro Gln Leu Pro Ser Glu Arg Ala Asp 
625                 630                 635                 640


Ser Pro Ala Gly Pro Glu Ser Ser Arg Arg Ser Gly Pro Gly Pro Pro 
                645                 650                 655


Glu Leu Asp Ser Glu Gln Pro Ser Arg Leu Phe Gly Gln Glu Glu Leu 
            660                 665                 670


Asp Pro Asp Ser Leu Ser Asp Ala Ser Gly Ser Asp Gly Gly Arg Gly 
        675                 680                 685


Pro Glu Pro Gly Val Glu Pro Gln Asp Ser Arg Arg Arg Ser Pro Gln 
    690                 695                 700


Glu Gly Pro Thr Trp Ser Arg Gly Arg Arg Ser Pro Arg Ala Pro Gly 
705                 710                 715                 720


Glu Pro Thr Pro Ala Ser Phe Phe Ile Gly Asp Gln Asn Gly Asp Ala 
                725                 730                 735


Val Leu Ser Arg Lys Pro Leu Ala Ala Pro Gly Asp Gly Glu Gly Leu 
            740                 745                 750


Gly Gln Thr Ala Gln Pro Ser Pro Pro Ala Arg Asp Gly Val Tyr Val 
        755                 760                 765


Ser Ala Asn Gly Arg Met Val Ile Gln Leu Arg Pro Gly Arg Ser Pro 
    770                 775                 780


Glu Pro Asp Gly Pro Ala Pro Ala Phe Leu Arg Gln Glu Ser Phe Thr 
785                 790                 795                 800


Lys Glu Pro Ala Ser Gly Pro Pro Ala Pro Gly Lys Pro Pro His Ile 
                805                 810                 815


Ser Ser His Pro Leu Leu Gln Asp Leu Ala Ala Thr Arg Ala Ala Arg 
            820                 825                 830


Met Asp Phe His Ser Gln Asp Thr His Leu Ile Leu Lys Glu Thr Glu 
        835                 840                 845


Thr Ala Leu Ala Ala Leu Glu Ala Arg Leu Leu Ser Asn Ser Val Asp 
    850                 855                 860


Ala Glu Cys Glu Gly Gly Ser Thr Pro Arg Pro Pro Glu Asp Ala Leu 
865                 870                 875                 880


Ser Gly Asp Ser Asp Val Asp Thr Ala Ser Thr Val Ser Leu Arg Ser 
                885                 890                 895


Gly Lys Ser Gly Pro Ser Pro Thr Thr Pro Gln Pro Leu Arg Ala Gln 
            900                 905                 910


Lys Glu Met Ser Pro Ser Pro Pro Ala Ala Gln Asp Pro Gly Gly Thr 
        915                 920                 925


Ala Leu Val Ser Ala Arg Glu Gln Ser Ser Glu Arg Gln His His Pro 
    930                 935                 940


Leu Gly Pro Thr Asp Met Gly Arg Gly Glu Pro Val Arg Arg Ser Ala 
945                 950                 955                 960


Ile Arg Arg Gly His Arg Pro Arg Gly Ser Leu Asp Trp Pro Ser Glu 
                965                 970                 975


Glu Arg Gly Pro Val Leu Ala His Leu Pro Ser Ser Asp Val Met Ala 
            980                 985                 990


Ser Asn His Glu Thr Pro Glu Ala Thr Gly Ala Gly Arg Leu Gly Ser 
        995                 1000                1005


Arg Arg Lys Pro Ala Ala Pro Pro Pro Ser Pro Ala Ala Arg Glu Glu 
    1010                1015                1020


Gln Ser Arg Ser Ser Ala Ser Ser Gln Lys Gly Pro Gln Ala Leu Thr 
1025                1030                1035                1040


Arg Ser Asn Ser Leu Ser Thr Pro Arg Pro Thr Arg Ala Ser Arg Leu 
                1045                1050                1055


Arg Arg Ala Arg Leu Gly Asp Ala Ser Asp Thr Glu Ala Ala Asp Gly 
            1060                1065                1070


Glu Arg Gly Ser Leu Gly Asn Pro Glu Pro Val Gly Arg Pro Ala Ala 
        1075                1080                1085


Glu Gln Ala Lys Lys Leu Ser Arg Leu Asp Ile Leu Ala Met Pro Arg 
    1090                1095                1100


Lys Arg Ala Gly Ser Phe Thr Gly Thr Ser Asp Pro Glu Ala Ala Pro 
1105                1110                1115                1120


Ala Arg Thr Ser Phe Ser Gly Arg Ser Val Glu Leu Cys Cys Ala Ser 
                1125                1130                1135


Arg Lys Pro Thr Met Ala Glu Ala Arg Ala Val Ser Arg Lys Ala Ala 
            1140                1145                1150


Asn Thr Ala Thr Thr Thr Gly Pro Arg Gln Pro Phe Ser Arg Ala Arg 
        1155                1160                1165


Ser Gly Ser Ala Arg Tyr Thr Ser Thr Thr Gln Thr Pro Arg Ala Gly 
    1170                1175                1180


Ser Ser Ser Arg Ala Arg Ser Arg Ala Pro Gly Pro Arg Asp Thr Asp 
1185                1190                1195                1200


Asp Asp Glu Glu Glu Pro Asp Pro Tyr Gly Phe Ile Val Gln Thr Ala 
                1205                1210                1215


Glu Ile Ala Glu Ile Ala Arg Leu Ser Gln Thr Leu Val Lys Asp Val 
            1220                1225                1230


Ala Ile Leu Ala Gln Glu Ile His Asp Val Ala Gly Asp Gly Asp Thr 
        1235                1240                1245


Leu Gly Ser Ser Glu Pro Ala His Ser Ala Ser Leu Ser Asn Met Pro 
    1250                1255                1260


Ser Thr Pro Ala Ser Thr Ile Ser Ala Arg Glu Glu Leu Val Gln Arg 
1265                1270                1275                1280


Ile Pro Glu Ala Ser Leu Asn Phe Gln Lys Val Pro Pro Gly Ser Leu 
                1285                1290                1295


Asn Ser Arg Asp Phe Asp Gln Asn Met Asn Asp Ser Cys Glu Asp Ala 
            1300                1305                1310


Leu Ala Asn Lys Thr Arg Pro Arg Asn Arg Glu Glu Ala Arg 
        1315                1320                1325


<210>  8768
<211>  490
<212>  DNA
<213>  Homo sapiens

<400>  8768
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aaatcagctg    300

gacatcatct ccatggcgga gacaaccatg atgccagagg agattgagct ggagatggca    360

aaaattcagc gtctccggga agtcttggtc cgccgggagt ctgagctcag gttcatgatg    420

gatgacatcc agctctgcaa ggacatcatg gacttgaagc aggagctgca gaacttggtc    480

gccatcccag                                                           490


<210>  8769
<211>  100
<212>  PRT
<213>  Homo sapiens

<400>  8769

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Asn Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met 
        35                  40                  45


Met Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg 
    50                  55                  60


Glu Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp 
65                  70                  75                  80


Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn 
                85                  90                  95


Leu Val Ala Ile 
            100


<210>  8770
<211>  1145
<212>  DNA
<213>  Homo sapiens

<400>  8770
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aaatcagctg    300

gacatcatct ccatggcgga gacaaccatg atgccagagg agattgagct ggagatggca    360

aaaattcagc gtctccggga agtcttggtc cgccgggagt ctgagctcag gttcatgatg    420

gatgacatcc agctctgcaa ggacatcatg gacttgaagc aggagctgca gaacttggtc    480

gccatcccag aaaaagaaaa aaccaaactg cagaagcaga gagaggatga gctaatccag    540

aagatccaca aactggtgca gaagagagac ttcctggtgg acgatgcgga ggtcgagcgg    600

ttaaggtgag tgcactgcgg gtacccgatc actgggctgc aggacagcaa ccttctgctt    660

ccttccagaa cccatcttct gctcctggga ctcacagcct tgcctaacag gcatggcctt    720

gatccacagt ctctggacac tgaatcccaa ggaaccccag ccttctggct tgagaattca    780

ttttgtatat aagagaattt caaatctgtg cctcttgagg gaatgttgtt ccaggaagtg    840

accagggagg agtcacatcc cataatacat ggcagagctt ccttcacatc ctgtcactcc    900

tgaaggcaat gtcttgaaac ttctgctatc agtttctacc gaaactctgc cacctgaact    960

gacttgctcc caacctctgt cctcccaacc tcccagcttt gttctcccct ttcccttccc   1020

cttagtggcg ccaatgccct tttctaagta tcagggtctt ctctttgcat ctgctgcctt   1080

gacctcgaca accacagccc tggagctgca gtgtaaaaac atgttgtaaa tgttgaaaat   1140

gtgga                                                               1145


<210>  8771
<211>  140
<212>  PRT
<213>  Homo sapiens

<400>  8771

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Asn Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met 
        35                  40                  45


Met Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg 
    50                  55                  60


Glu Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp 
65                  70                  75                  80


Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn 
                85                  90                  95


Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln Arg 
            100                 105                 110


Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys Arg Asp 
        115                 120                 125


Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg 
    130                 135                 140


<210>  8772
<211>  1364
<212>  DNA
<213>  Homo sapiens

<400>  8772
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aagtgactct    300

ccaaggcaga aggggttgaa ggcaagcccg tgactgtcac cagaggccat gggcacggca    360

ggcgggcctg gccaccctgt acagagtgta gcagtaggga gtctctcacc gtcgcatggt    420

cctccccaga gcatgccgaa cccaggagtc tgtctcactg tttatccaaa caccaggaaa    480

ggtcctccct caaaaaagca tatctccact tctctctagc tgtatctaac ccaccgtgtg    540

aatgaactgg gagaggggca tgctccccag ctgtgtgtag tcgtgacttc tcaacaatct    600

agcaccatgt cggacacgtt ccccatccac cctcctagct ctgctctcag agctaggcac    660

atgggcacag gtcccctccc gtctgtcctc tcccagcaac tgtgccctgg agggctccac    720

atggcccccg tgtctctcgg gcaccaccca tatagcagtc ccagagggcc catctgtaaa    780

gatcgagctt gtgtgtggtg tcgtggtcac atctcccgct tccccccatc ctgtgtctgg    840

gcacagttca catcaggaca gcgtccattg tgctctcagt ctgcctcagg tgtgtgcctg    900

gagggggcct ggactggcat ggatccagtg tgcagaagag ccagcaggga accggaagct    960

ctgatgtcaa ggccagagca gttgagaatg ggacccagag tagatgctga cctgggcact   1020

ccaccattcc ggggccacca cagagatgcc agcaggatgc cactttgcca gcccgacaca   1080

cggacctttg taaagaacag caacaggcag gagaggcagc gtgtgaccag attgtgtccc   1140

gtcattgggt ggcatatgtt aactagctgc caaacaactt caacccgtgt aattcatgta   1200

catttgcaac agccagcccg gtacagcctg tgtgacttct ctgtatgtgt gtgtgtgtcg   1260

tgaccagcct aagtagttag cataactcaa gatgctgatg tgcagtcacc catcagagaa   1320

aataaaaatg gaaaccacgt tcacagcatt ttaaaagttt ttac                    1364


<210>  8773
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  8773

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Ser Asp Ser Pro Arg Gln Lys Gly Leu Lys Ala Ser Pro 
        35                  40                  45


<210>  8774
<211>  1952
<212>  DNA
<213>  Homo sapiens

<400>  8774
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aaatcagctg    300

gacatcatct ccatggcgga gacaaccatg atgccagagg agattgagct ggagatggca    360

aaaattcagc gtctccggga agtcttggtc cgccgggagt ctgagctcag gttcatgatg    420

gatgacatcc agctctgcaa ggacatcatg gacttgaagc aggagctgca gaacttggtc    480

gccatcccag aaaaagaaaa aaccaaactg cagaagcaga gagaggatga gctaatccag    540

aagatccaca aactggtgca gaagagagac ttcctggtgg acgatgcgga ggtcgagcgg    600

ttaagggagc aagaagaaga caaggaaatg gctgatttcc tgagaatcaa gttaaaacct    660

ctagacaaag taaccaaatc tccagccagc tcccgggcag agaagaaagc agagccccca    720

cctagcaagc ccacggtggc caagacgggg ctggcactga tcaaggattg ttgcggggcc    780

acccagtgca acatcatgta gcccccacgt ggggtgccct gggccatggg gacccccccc    840

caccctcttg tctttatagc ccccatttca ccggggccca agagctctcc aaggcagaag    900

gggttgaagg caagcccgtg actgtcacca gaggccatgg gcacggcagg cgggcctggc    960

caccctgtac agagtgtagc agtagggagt ctctcaccgt cgcatggtcc tccccagagc   1020

atgccgaacc caggagtctg tctcactgtt tatccaaaca ccaggaaagg tcctccctca   1080

aaaaagcata tctccacttc tctctagctg tatctaaccc accgtgtgaa tgaactggga   1140

gaggggcatg ctccccagct gtgtgtagtc gtgacttctc aacaatctag caccatgtcg   1200

gacacgttcc ccatccaccc tcctagctct gctctcagag ctaggcacat gggcacaggt   1260

cccctcccgt ctgtcctctc ccagcaactg tgccctggag ggctccacat ggcccccgtg   1320

tctctcgggc accacccata tagcagtccc agagggccca tctgtaaaga tcgagcttgt   1380

gtgtggtgtc gtggtcacat ctcccgcttc cccccatcct gtgtctgggc acagttcaca   1440

tcaggacagc gtccattgtg ctctcagtct gcctcaggtg tgtgcctgga gggggcctgg   1500

actggcatgg atccagtgtg cagaagagcc agcagggaac cggaagctct gatgtcaagg   1560

ccagagcagt tgagaatggg acccagagta gatgctgacc tgggcactcc accattccgg   1620

ggccaccaca gagatgccag caggatgcca ctttgccagc ccgacacacg gacctttgta   1680

aagaacagca acaggcagga gaggcagcgt gtgaccagat tgtgtcccgt cattgggtgg   1740

catatgttaa ctagctgcca aacaacttca acccgtgtaa ttcatgtaca tttgcaacag   1800

ccagcccggt acagcctgtg tgacttctct gtatgtgtgt gtgtgtcgtg accagcctaa   1860

gtagttagca taactcaaga tgctgatgtg cagtcaccca tcagagaaaa taaaaatgga   1920

aaccacgttc acagcatttt aaaagttttt ac                                 1952


<210>  8775
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  8775

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Asn Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met 
        35                  40                  45


Met Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg 
    50                  55                  60


Glu Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp 
65                  70                  75                  80


Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn 
                85                  90                  95


Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln Arg 
            100                 105                 110


Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys Arg Asp 
        115                 120                 125


Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu Gln Glu Glu 
    130                 135                 140


Asp Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp 
145                 150                 155                 160


Lys Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu 
                165                 170                 175


Pro Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile 
            180                 185                 190


Lys Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
        195                 200


<210>  8776
<211>  2232
<212>  DNA
<213>  Homo sapiens

<400>  8776
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aaatcagctg    300

gacatcatct ccatggcgga gacaaccatg atgccagagg agattgagct ggagatggca    360

aaaattcagc gtctccggga agtcttggtc cgccgggagt ctgagctcag gttcatgatg    420

gatgacatcc agctctgcaa ggacatcatg gacttgaagc aggagctgca gaacttggtc    480

gccatcccag aaaaagaaaa aaccaaactg cagaagcaga gagaggatga gctaatccag    540

aagatccaca aactggtgca gaagagagac ttcctggtgg acgatgcgga ggtcgagcgg    600

ttaagggagc aagaagaaga caaggaaatg gctgatttcc tgagaatcaa gttaaaacct    660

ctagacaaag taaccaaatc tccagccagc tcccgggcag agaagaaagc agagccccca    720

cctagcaagc ccacggtggc caagacgggg ctggcactga tcaaggattg ttgcggggcc    780

acccagtgca acatcatgta gcccccacgt ggggtgccct gggccatggg gacccccccc    840

caccctcttg tctttatagc ccccatttca ccggggccca agagctctcc aaggcagaag    900

gggttgaagg caagcccgtg actgtcacca gaggccatgg gcacggcagg cgggcctggc    960

caccctgtac agagtgtagc agtagggagt ctctcaccgt cgcatggtcc tccccagagc   1020

atgccgaacc caggagtctg tctcactgtt tatccaaaca ccaggaaagg tcctccctca   1080

aaaaagcata tctccacttc tctctagctg tatctaaccc accgtgtgaa tgaactggga   1140

gaggggcatg ctccccagct gtgtgtagtc gtgacttctc aacaatctag caccatgtcg   1200

gacacgttcc ccatccaccc tcctagctct gctctcagag ctaggcacat gggcacaggt   1260

cccctcccgt ctgtcctctc ccagcaactg tgccctggag ggctccacat ggcccccgtg   1320

tctctcgggc accacccata tagcagtccc agagggccca tctgtaaaga tcgagcttgt   1380

gtgtggtgtc gtggtcacat ctcccgcttc cccccatcct gtgtctgggc acagttcaca   1440

tcaggacagc gtccattgtg ctctcagtct gcctcaggtg tgtgcctgga gggggcctgg   1500

actggcatgg atccagtgtg cagaagagcc agcagggaac cggaagctct gatgtcaagg   1560

ccagagcagt tgagaatggg acccagagta gatgctgacc tgggcactcc accattccgg   1620

ggccaccaca gagatgccag caggatgcca ctttgccagc ccgacacacg gacctttgta   1680

aagaacagca acaggcagga gaggcagcgt gtgaccagat tgtgtcccgt cattgggtgg   1740

catatgttaa ctagctgcca aacaacttca acccgtgtaa ttcatgtaca tttgcaacag   1800

ccagcccggt acagcctgtg tgacttctct gtatgtgtgt gtgtgtcgtg accagcctaa   1860

gtagttagca taactcaaga tgctgatgtg cagtcaccca tcagagaaaa taaaaatgga   1920

aaccacgttc acagcatttt aaaagttttt actttttttc ttgattatgg aagtaatcca   1980

tgtacatagt aaatcatttt aaaagtacaa aaagtatgaa gaagtttgtc ttaaaaaaaa   2040

aaaaaattat tcctccaact agagaccact ctgatgtttc gacgttttaa aaaagtcttt   2100

ttttgtgcat tttttcatcg ttgacatcat attgtggtat catttataac cagttttttc   2160

ctacttatta taccaccatc ttccacatca ttaaaagctc tttgtaaaca ttaaacactc   2220

ttcataaatc at                                                       2232


<210>  8777
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  8777

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Asn Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met 
        35                  40                  45


Met Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg 
    50                  55                  60


Glu Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp 
65                  70                  75                  80


Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn 
                85                  90                  95


Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln Arg 
            100                 105                 110


Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys Arg Asp 
        115                 120                 125


Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu Gln Glu Glu 
    130                 135                 140


Asp Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp 
145                 150                 155                 160


Lys Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu 
                165                 170                 175


Pro Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile 
            180                 185                 190


Lys Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
        195                 200


<210>  8778
<211>  1644
<212>  DNA
<213>  Homo sapiens

<400>  8778
gtgcatccct gccccttctg ggtacccgta ggcgctcccg ggcgctggcg gcggcggagg     60

agagggagca gcgtcacggg cgcccggccc gttaaaacgc tgctggctgg agccacctcc    120

ctccctgcag cccgcaacgg gaatggagta aagggagacc cgtcgacctg gccacgggga    180

tcagcgatgg aattaaagca atctttgtcc acccatctgg aagccgagaa gcctctgagg    240

cgctatgggg cggtggagga gacggcttgg aaaacggaga gactggggag aagtgactct    300

ccaaggcaga aggggttgaa ggcaagcccg tgactgtcac cagaggccat gggcacggca    360

ggcgggcctg gccaccctgt acagagtgta gcagtaggga gtctctcacc gtcgcatggt    420

cctccccaga gcatgccgaa cccaggagtc tgtctcactg tttatccaaa caccaggaaa    480

ggtcctccct caaaaaagca tatctccact tctctctagc tgtatctaac ccaccgtgtg    540

aatgaactgg gagaggggca tgctccccag ctgtgtgtag tcgtgacttc tcaacaatct    600

agcaccatgt cggacacgtt ccccatccac cctcctagct ctgctctcag agctaggcac    660

atgggcacag gtcccctccc gtctgtcctc tcccagcaac tgtgccctgg agggctccac    720

atggcccccg tgtctctcgg gcaccaccca tatagcagtc ccagagggcc catctgtaaa    780

gatcgagctt gtgtgtggtg tcgtggtcac atctcccgct tccccccatc ctgtgtctgg    840

gcacagttca catcaggaca gcgtccattg tgctctcagt ctgcctcagg tgtgtgcctg    900

gagggggcct ggactggcat ggatccagtg tgcagaagag ccagcaggga accggaagct    960

ctgatgtcaa ggccagagca gttgagaatg ggacccagag tagatgctga cctgggcact   1020

ccaccattcc ggggccacca cagagatgcc agcaggatgc cactttgcca gcccgacaca   1080

cggacctttg taaagaacag caacaggcag gagaggcagc gtgtgaccag attgtgtccc   1140

gtcattgggt ggcatatgtt aactagctgc caaacaactt caacccgtgt aattcatgta   1200

catttgcaac agccagcccg gtacagcctg tgtgacttct ctgtatgtgt gtgtgtgtcg   1260

tgaccagcct aagtagttag cataactcaa gatgctgatg tgcagtcacc catcagagaa   1320

aataaaaatg gaaaccacgt tcacagcatt ttaaaagttt ttactttttt tcttgattat   1380

ggaagtaatc catgtacata gtaaatcatt ttaaaagtac aaaaagtatg aagaagtttg   1440

tcttaaaaaa aaaaaaaatt attcctccaa ctagagacca ctctgatgtt tcgacgtttt   1500

aaaaaagtct ttttttgtgc attttttcat cgttgacatc atattgtggt atcatttata   1560

accagttttt tcctacttat tataccacca tcttccacat cattaaaagc tctttgtaaa   1620

cattaaacac tcttcataaa tcat                                          1644


<210>  8779
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  8779

Met Glu Leu Lys Gln Ser Leu Ser Thr His Leu Glu Ala Glu Lys Pro 
1               5                   10                  15


Leu Arg Arg Tyr Gly Ala Val Glu Glu Thr Ala Trp Lys Thr Glu Arg 
            20                  25                  30


Leu Gly Arg Ser Asp Ser Pro Arg Gln Lys Gly Leu Lys Ala Ser Pro 
        35                  40                  45


<210>  8780
<211>  1272
<212>  DNA
<213>  Homo sapiens

<400>  8780
ggcgctcccg ggcgctggcg gcggcggagg agagggagca gcgtcacggg cgcccggccc     60

gttaaaacgc tgctggctgg agccacctcc ctccctgcag cccgcaacgg gaatggagta    120

aagggagacc cgtcgacctg gccacgggga tcagcgatgg aattaaagca atcttttagc    180

ccccatttca ccggggccca agagctctcc aaggcagaag gggttgaagg caagcccgtg    240

actgtcacca gaggccatgg gcacggcagg cgggcctggc caccctgtac agagtgtagc    300

agtagggagt ctctcaccgt cgcatggtcc tccccagagc atgccgaacc caggagtctg    360

tctcactgtt tatccaaaca ccaggaaagg tcctccctca aaaaagcata tctccacttc    420

tctctagctg tatctaaccc accgtgtgaa tgaactggga gaggggcatg ctccccagct    480

gtgtgtagtc gtgacttctc aacaatctag caccatgtcg gacacgttcc ccatccaccc    540

tcctagctct gctctcagag ctaggcacat gggcacaggt cccctcccgt ctgtcctctc    600

ccagcaactg tgccctggag ggctccacat ggcccccgtg tctctcgggc accacccata    660

tagcagtccc agagggccca tctgtaaaga tcgagcttgt gtgtggtgtc gtggtcacat    720

ctcccgcttc cccccatcct gtgtctgggc acagttcaca tcaggacagc gtccattgtg    780

ctctcagtct gcctcaggtg tgtgcctgga gggggcctgg actggcatgg atccagtgtg    840

cagaagagcc agcagggaac cggaagctct gatgtcaagg ccagagcagt tgagaatggg    900

acccagagta gatgctgacc tgggcactcc accattccgg ggccaccaca gagatgccag    960

caggatgcca ctttgccagc ccgacacacg gacctttgta aagaacagca acaggcagga   1020

gaggcagcgt gtgaccagat tgtgtcccgt cattgggtgg catatgttaa ctagctgcca   1080

aacaacttca acccgtgtaa ttcatgtaca tttgcaacag ccagcccggt acagcctgtg   1140

tgacttctct gtatgtgtgt gtgtgtcgtg accagcctaa gtagttagca taactcaaga   1200

tgctgatgtg cagtcaccca tcagagaaaa taaaaatgga aaccacgttc acagcatttt   1260

aaaagttttt ac                                                       1272


<210>  8781
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  8781

Met Glu Leu Lys Gln Ser Phe Ser Pro His Phe Thr Gly Ala Gln Glu 
1               5                   10                  15


Leu Ser Lys Ala Glu Gly Val Glu Gly Lys Pro Val Thr Val Thr Arg 
            20                  25                  30


Gly His Gly His Gly Arg Arg Ala Trp Pro Pro Cys Thr Glu Cys Ser 
        35                  40                  45


Ser Arg Glu Ser Leu Thr Val Ala Trp Ser Ser Pro Glu His Ala Glu 
    50                  55                  60


Pro Arg Ser Leu Ser His Cys Leu Ser Lys His Gln Glu Arg Ser Ser 
65                  70                  75                  80


Leu Lys Lys Ala Tyr Leu His Phe Ser Leu Ala Val Ser Asn Pro Pro 
                85                  90                  95


Cys Glu 



<210>  8782
<211>  1552
<212>  DNA
<213>  Homo sapiens

<400>  8782
ggcgctcccg ggcgctggcg gcggcggagg agagggagca gcgtcacggg cgcccggccc     60

gttaaaacgc tgctggctgg agccacctcc ctccctgcag cccgcaacgg gaatggagta    120

aagggagacc cgtcgacctg gccacgggga tcagcgatgg aattaaagca atcttttagc    180

ccccatttca ccggggccca agagctctcc aaggcagaag gggttgaagg caagcccgtg    240

actgtcacca gaggccatgg gcacggcagg cgggcctggc caccctgtac agagtgtagc    300

agtagggagt ctctcaccgt cgcatggtcc tccccagagc atgccgaacc caggagtctg    360

tctcactgtt tatccaaaca ccaggaaagg tcctccctca aaaaagcata tctccacttc    420

tctctagctg tatctaaccc accgtgtgaa tgaactggga gaggggcatg ctccccagct    480

gtgtgtagtc gtgacttctc aacaatctag caccatgtcg gacacgttcc ccatccaccc    540

tcctagctct gctctcagag ctaggcacat gggcacaggt cccctcccgt ctgtcctctc    600

ccagcaactg tgccctggag ggctccacat ggcccccgtg tctctcgggc accacccata    660

tagcagtccc agagggccca tctgtaaaga tcgagcttgt gtgtggtgtc gtggtcacat    720

ctcccgcttc cccccatcct gtgtctgggc acagttcaca tcaggacagc gtccattgtg    780

ctctcagtct gcctcaggtg tgtgcctgga gggggcctgg actggcatgg atccagtgtg    840

cagaagagcc agcagggaac cggaagctct gatgtcaagg ccagagcagt tgagaatggg    900

acccagagta gatgctgacc tgggcactcc accattccgg ggccaccaca gagatgccag    960

caggatgcca ctttgccagc ccgacacacg gacctttgta aagaacagca acaggcagga   1020

gaggcagcgt gtgaccagat tgtgtcccgt cattgggtgg catatgttaa ctagctgcca   1080

aacaacttca acccgtgtaa ttcatgtaca tttgcaacag ccagcccggt acagcctgtg   1140

tgacttctct gtatgtgtgt gtgtgtcgtg accagcctaa gtagttagca taactcaaga   1200

tgctgatgtg cagtcaccca tcagagaaaa taaaaatgga aaccacgttc acagcatttt   1260

aaaagttttt actttttttc ttgattatgg aagtaatcca tgtacatagt aaatcatttt   1320

aaaagtacaa aaagtatgaa gaagtttgtc ttaaaaaaaa aaaaaattat tcctccaact   1380

agagaccact ctgatgtttc gacgttttaa aaaagtcttt ttttgtgcat tttttcatcg   1440

ttgacatcat attgtggtat catttataac cagttttttc ctacttatta taccaccatc   1500

ttccacatca ttaaaagctc tttgtaaaca ttaaacactc ttcataaatc at           1552


<210>  8783
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  8783

Met Glu Leu Lys Gln Ser Phe Ser Pro His Phe Thr Gly Ala Gln Glu 
1               5                   10                  15


Leu Ser Lys Ala Glu Gly Val Glu Gly Lys Pro Val Thr Val Thr Arg 
            20                  25                  30


Gly His Gly His Gly Arg Arg Ala Trp Pro Pro Cys Thr Glu Cys Ser 
        35                  40                  45


Ser Arg Glu Ser Leu Thr Val Ala Trp Ser Ser Pro Glu His Ala Glu 
    50                  55                  60


Pro Arg Ser Leu Ser His Cys Leu Ser Lys His Gln Glu Arg Ser Ser 
65                  70                  75                  80


Leu Lys Lys Ala Tyr Leu His Phe Ser Leu Ala Val Ser Asn Pro Pro 
                85                  90                  95


Cys Glu 



<210>  8784
<211>  1793
<212>  DNA
<213>  Homo sapiens

<400>  8784
tcccgggcgc tggcggcggc ggaggagagg gagcagcgtc acgggcgccc ggcccgttaa     60

aacgctgctg gctggagcca cctccctccc tgcagcccgc aacgggaatg gagtaaaggg    120

agacccgtcg acctggccac ggggatcagc gatggaatta aagcaatctt tgtccaccca    180

tctggaagcc gagaagcctc tgaggcgcta tggggcggtg gaggagacgg cttggaaaac    240

ggagagactg gggagaagat ggatgacatc cagctctgca aggacatcat ggacttgaag    300

caggagctgc agaacttggt cgccatccca gaaaaagaaa aaaccaaact gcagaagcag    360

agagaggatg agctaatcca gaagatccac aaactggtgc agaagagaga cttcctggtg    420

gacgatgcgg aggtcgagcg gttaagggag caagaagaag acaaggaaat ggctgatttc    480

ctgagaatca agttaaaacc tctagacaaa gtaaccaaat ctccagccag ctcccgggca    540

gagaagaaag cagagccccc acctagcaag cccacggtgg ccaagacggg gctggcactg    600

atcaaggatt gttgcggggc cacccagtgc aacatcatgt agcccccacg tggggtgccc    660

tgggccatgg ggaccccccc ccaccctctt gtctttatag cccccatttc accggggccc    720

aagagctctc caaggcagaa ggggttgaag gcaagcccgt gactgtcacc agaggccatg    780

ggcacggcag gcgggcctgg ccaccctgta cagagtgtag cagtagggag tctctcaccg    840

tcgcatggtc ctccccagag catgccgaac ccaggagtct gtctcactgt ttatccaaac    900

accaggaaag gtcctccctc aaaaaagcat atctccactt ctctctagct gtatctaacc    960

caccgtgtga atgaactggg agaggggcat gctccccagc tgtgtgtagt cgtgacttct   1020

caacaatcta gcaccatgtc ggacacgttc cccatccacc ctcctagctc tgctctcaga   1080

gctaggcaca tgggcacagg tcccctcccg tctgtcctct cccagcaact gtgccctgga   1140

gggctccaca tggcccccgt gtctctcggg caccacccat atagcagtcc cagagggccc   1200

atctgtaaag atcgagcttg tgtgtggtgt cgtggtcaca tctcccgctt ccccccatcc   1260

tgtgtctggg cacagttcac atcaggacag cgtccattgt gctctcagtc tgcctcaggt   1320

gtgtgcctgg agggggcctg gactggcatg gatccagtgt gcagaagagc cagcagggaa   1380

ccggaagctc tgatgtcaag gccagagcag ttgagaatgg gacccagagt agatgctgac   1440

ctgggcactc caccattccg gggccaccac agagatgcca gcaggatgcc actttgccag   1500

cccgacacac ggacctttgt aaagaacagc aacaggcagg agaggcagcg tgtgaccaga   1560

ttgtgtcccg tcattgggtg gcatatgtta actagctgcc aaacaacttc aacccgtgta   1620

attcatgtac atttgcaaca gccagcccgg tacagcctgt gtgacttctc tgtatgtgtg   1680

tgtgtgtcgt gaccagccta agtagttagc ataactcaag atgctgatgt gcagtcaccc   1740

atcagagaaa ataaaaatgg aaaccacgtt cacagcattt taaaagtttt tac          1793


<210>  8785
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  8785

Met Asp Asp Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu 
1               5                   10                  15


Leu Gln Asn Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln 
            20                  25                  30


Lys Gln Arg Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln 
        35                  40                  45


Lys Arg Asp Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu 
    50                  55                  60


Gln Glu Glu Asp Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys 
65                  70                  75                  80


Pro Leu Asp Lys Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys 
                85                  90                  95


Lys Ala Glu Pro Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu 
            100                 105                 110


Ala Leu Ile Lys Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
        115                 120                 125


<210>  8786
<211>  2073
<212>  DNA
<213>  Homo sapiens

<400>  8786
tcccgggcgc tggcggcggc ggaggagagg gagcagcgtc acgggcgccc ggcccgttaa     60

aacgctgctg gctggagcca cctccctccc tgcagcccgc aacgggaatg gagtaaaggg    120

agacccgtcg acctggccac ggggatcagc gatggaatta aagcaatctt tgtccaccca    180

tctggaagcc gagaagcctc tgaggcgcta tggggcggtg gaggagacgg cttggaaaac    240

ggagagactg gggagaagat ggatgacatc cagctctgca aggacatcat ggacttgaag    300

caggagctgc agaacttggt cgccatccca gaaaaagaaa aaaccaaact gcagaagcag    360

agagaggatg agctaatcca gaagatccac aaactggtgc agaagagaga cttcctggtg    420

gacgatgcgg aggtcgagcg gttaagggag caagaagaag acaaggaaat ggctgatttc    480

ctgagaatca agttaaaacc tctagacaaa gtaaccaaat ctccagccag ctcccgggca    540

gagaagaaag cagagccccc acctagcaag cccacggtgg ccaagacggg gctggcactg    600

atcaaggatt gttgcggggc cacccagtgc aacatcatgt agcccccacg tggggtgccc    660

tgggccatgg ggaccccccc ccaccctctt gtctttatag cccccatttc accggggccc    720

aagagctctc caaggcagaa ggggttgaag gcaagcccgt gactgtcacc agaggccatg    780

ggcacggcag gcgggcctgg ccaccctgta cagagtgtag cagtagggag tctctcaccg    840

tcgcatggtc ctccccagag catgccgaac ccaggagtct gtctcactgt ttatccaaac    900

accaggaaag gtcctccctc aaaaaagcat atctccactt ctctctagct gtatctaacc    960

caccgtgtga atgaactggg agaggggcat gctccccagc tgtgtgtagt cgtgacttct   1020

caacaatcta gcaccatgtc ggacacgttc cccatccacc ctcctagctc tgctctcaga   1080

gctaggcaca tgggcacagg tcccctcccg tctgtcctct cccagcaact gtgccctgga   1140

gggctccaca tggcccccgt gtctctcggg caccacccat atagcagtcc cagagggccc   1200

atctgtaaag atcgagcttg tgtgtggtgt cgtggtcaca tctcccgctt ccccccatcc   1260

tgtgtctggg cacagttcac atcaggacag cgtccattgt gctctcagtc tgcctcaggt   1320

gtgtgcctgg agggggcctg gactggcatg gatccagtgt gcagaagagc cagcagggaa   1380

ccggaagctc tgatgtcaag gccagagcag ttgagaatgg gacccagagt agatgctgac   1440

ctgggcactc caccattccg gggccaccac agagatgcca gcaggatgcc actttgccag   1500

cccgacacac ggacctttgt aaagaacagc aacaggcagg agaggcagcg tgtgaccaga   1560

ttgtgtcccg tcattgggtg gcatatgtta actagctgcc aaacaacttc aacccgtgta   1620

attcatgtac atttgcaaca gccagcccgg tacagcctgt gtgacttctc tgtatgtgtg   1680

tgtgtgtcgt gaccagccta agtagttagc ataactcaag atgctgatgt gcagtcaccc   1740

atcagagaaa ataaaaatgg aaaccacgtt cacagcattt taaaagtttt tacttttttt   1800

cttgattatg gaagtaatcc atgtacatag taaatcattt taaaagtaca aaaagtatga   1860

agaagtttgt cttaaaaaaa aaaaaaatta ttcctccaac tagagaccac tctgatgttt   1920

cgacgtttta aaaaagtctt tttttgtgca ttttttcatc gttgacatca tattgtggta   1980

tcatttataa ccagtttttt cctacttatt ataccaccat cttccacatc attaaaagct   2040

ctttgtaaac attaaacact cttcataaat cat                                2073


<210>  8787
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  8787

Met Asp Asp Ile Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu 
1               5                   10                  15


Leu Gln Asn Leu Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln 
            20                  25                  30


Lys Gln Arg Glu Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln 
        35                  40                  45


Lys Arg Asp Phe Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu 
    50                  55                  60


Gln Glu Glu Asp Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys 
65                  70                  75                  80


Pro Leu Asp Lys Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys 
                85                  90                  95


Lys Ala Glu Pro Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu 
            100                 105                 110


Ala Leu Ile Lys Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
        115                 120                 125


<210>  8788
<211>  1831
<212>  DNA
<213>  Homo sapiens

<400>  8788
ggctggggaa acagaaactc gcagaagtta aaaaaatgtg cttgaggtgc cactggagaa     60

taacaatcat agccaggatg tgaagcctgt cagtttcctc agccgcaaat tcttccatgt    120

ggggcgacct cacagagacg ggatgtatgg gacggcggag tgcaaagaaa gatcagctgg    180

acatcatctc catggcggag acaaccatga tgccagagga gattgagctg gagatggcaa    240

aaattcagcg tctccgggaa gtcttggtcc gccgggagtc tgagctcagg ttcatgatgg    300

atgacatcca gctctgcaag gacatcatgg acttgaagca ggagctgcag aacttggtcg    360

ccatcccaga aaaagaaaaa accaaactgc agaagcagag agaggatgag ctaatccaga    420

agatccacaa actggtgcag aagagagact tcctggtgga cgatgcggag gtcgagcggt    480

taagggagca agaagaagac aaggaaatgg ctgatttcct gagaatcaag ttaaaacctc    540

tagacaaagt aaccaaatct ccagccagct cccgggcaga gaagaaagca gagcccccac    600

ctagcaagcc cacggtggcc aagacggggc tggcactgat caaggattgt tgcggggcca    660

cccagtgcaa catcatgtag cccccacgtg gggtgccctg ggccatgggg accccccccc    720

accctcttgt ctttatagcc cccatttcac cggggcccaa gagctctcca aggcagaagg    780

ggttgaaggc aagcccgtga ctgtcaccag aggccatggg cacggcaggc gggcctggcc    840

accctgtaca gagtgtagca gtagggagtc tctcaccgtc gcatggtcct ccccagagca    900

tgccgaaccc aggagtctgt ctcactgttt atccaaacac caggaaaggt cctccctcaa    960

aaaagcatat ctccacttct ctctagctgt atctaaccca ccgtgtgaat gaactgggag   1020

aggggcatgc tccccagctg tgtgtagtcg tgacttctca acaatctagc accatgtcgg   1080

acacgttccc catccaccct cctagctctg ctctcagagc taggcacatg ggcacaggtc   1140

ccctcccgtc tgtcctctcc cagcaactgt gccctggagg gctccacatg gcccccgtgt   1200

ctctcgggca ccacccatat agcagtccca gagggcccat ctgtaaagat cgagcttgtg   1260

tgtggtgtcg tggtcacatc tcccgcttcc ccccatcctg tgtctgggca cagttcacat   1320

caggacagcg tccattgtgc tctcagtctg cctcaggtgt gtgcctggag ggggcctgga   1380

ctggcatgga tccagtgtgc agaagagcca gcagggaacc ggaagctctg atgtcaaggc   1440

cagagcagtt gagaatggga cccagagtag atgctgacct gggcactcca ccattccggg   1500

gccaccacag agatgccagc aggatgccac tttgccagcc cgacacacgg acctttgtaa   1560

agaacagcaa caggcaggag aggcagcgtg tgaccagatt gtgtcccgtc attgggtggc   1620

atatgttaac tagctgccaa acaacttcaa cccgtgtaat tcatgtacat ttgcaacagc   1680

cagcccggta cagcctgtgt gacttctctg tatgtgtgtg tgtgtcgtga ccagcctaag   1740

tagttagcat aactcaagat gctgatgtgc agtcacccat cagagaaaat aaaaatggaa   1800

accacgttca cagcatttta aaagttttta c                                  1831


<210>  8789
<211>  187
<212>  PRT
<213>  Homo sapiens

<400>  8789

Met Trp Gly Asp Leu Thr Glu Thr Gly Cys Met Gly Arg Arg Ser Ala 
1               5                   10                  15


Lys Lys Asp Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met Met 
            20                  25                  30


Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg Glu 
        35                  40                  45


Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp Ile 
    50                  55                  60


Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn Leu 
65                  70                  75                  80


Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln Arg Glu 
                85                  90                  95


Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys Arg Asp Phe 
            100                 105                 110


Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu Gln Glu Glu Asp 
        115                 120                 125


Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp Lys 
    130                 135                 140


Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu Pro 
145                 150                 155                 160


Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile Lys 
                165                 170                 175


Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
            180                 185


<210>  8790
<211>  2111
<212>  DNA
<213>  Homo sapiens

<400>  8790
ggctggggaa acagaaactc gcagaagtta aaaaaatgtg cttgaggtgc cactggagaa     60

taacaatcat agccaggatg tgaagcctgt cagtttcctc agccgcaaat tcttccatgt    120

ggggcgacct cacagagacg ggatgtatgg gacggcggag tgcaaagaaa gatcagctgg    180

acatcatctc catggcggag acaaccatga tgccagagga gattgagctg gagatggcaa    240

aaattcagcg tctccgggaa gtcttggtcc gccgggagtc tgagctcagg ttcatgatgg    300

atgacatcca gctctgcaag gacatcatgg acttgaagca ggagctgcag aacttggtcg    360

ccatcccaga aaaagaaaaa accaaactgc agaagcagag agaggatgag ctaatccaga    420

agatccacaa actggtgcag aagagagact tcctggtgga cgatgcggag gtcgagcggt    480

taagggagca agaagaagac aaggaaatgg ctgatttcct gagaatcaag ttaaaacctc    540

tagacaaagt aaccaaatct ccagccagct cccgggcaga gaagaaagca gagcccccac    600

ctagcaagcc cacggtggcc aagacggggc tggcactgat caaggattgt tgcggggcca    660

cccagtgcaa catcatgtag cccccacgtg gggtgccctg ggccatgggg accccccccc    720

accctcttgt ctttatagcc cccatttcac cggggcccaa gagctctcca aggcagaagg    780

ggttgaaggc aagcccgtga ctgtcaccag aggccatggg cacggcaggc gggcctggcc    840

accctgtaca gagtgtagca gtagggagtc tctcaccgtc gcatggtcct ccccagagca    900

tgccgaaccc aggagtctgt ctcactgttt atccaaacac caggaaaggt cctccctcaa    960

aaaagcatat ctccacttct ctctagctgt atctaaccca ccgtgtgaat gaactgggag   1020

aggggcatgc tccccagctg tgtgtagtcg tgacttctca acaatctagc accatgtcgg   1080

acacgttccc catccaccct cctagctctg ctctcagagc taggcacatg ggcacaggtc   1140

ccctcccgtc tgtcctctcc cagcaactgt gccctggagg gctccacatg gcccccgtgt   1200

ctctcgggca ccacccatat agcagtccca gagggcccat ctgtaaagat cgagcttgtg   1260

tgtggtgtcg tggtcacatc tcccgcttcc ccccatcctg tgtctgggca cagttcacat   1320

caggacagcg tccattgtgc tctcagtctg cctcaggtgt gtgcctggag ggggcctgga   1380

ctggcatgga tccagtgtgc agaagagcca gcagggaacc ggaagctctg atgtcaaggc   1440

cagagcagtt gagaatggga cccagagtag atgctgacct gggcactcca ccattccggg   1500

gccaccacag agatgccagc aggatgccac tttgccagcc cgacacacgg acctttgtaa   1560

agaacagcaa caggcaggag aggcagcgtg tgaccagatt gtgtcccgtc attgggtggc   1620

atatgttaac tagctgccaa acaacttcaa cccgtgtaat tcatgtacat ttgcaacagc   1680

cagcccggta cagcctgtgt gacttctctg tatgtgtgtg tgtgtcgtga ccagcctaag   1740

tagttagcat aactcaagat gctgatgtgc agtcacccat cagagaaaat aaaaatggaa   1800

accacgttca cagcatttta aaagttttta ctttttttct tgattatgga agtaatccat   1860

gtacatagta aatcatttta aaagtacaaa aagtatgaag aagtttgtct taaaaaaaaa   1920

aaaaattatt cctccaacta gagaccactc tgatgtttcg acgttttaaa aaagtctttt   1980

tttgtgcatt ttttcatcgt tgacatcata ttgtggtatc atttataacc agttttttcc   2040

tacttattat accaccatct tccacatcat taaaagctct ttgtaaacat taaacactct   2100

tcataaatca t                                                        2111


<210>  8791
<211>  187
<212>  PRT
<213>  Homo sapiens

<400>  8791

Met Trp Gly Asp Leu Thr Glu Thr Gly Cys Met Gly Arg Arg Ser Ala 
1               5                   10                  15


Lys Lys Asp Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met Met 
            20                  25                  30


Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg Glu 
        35                  40                  45


Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met Met Asp Asp Ile 
    50                  55                  60


Gln Leu Cys Lys Asp Ile Met Asp Leu Lys Gln Glu Leu Gln Asn Leu 
65                  70                  75                  80


Val Ala Ile Pro Glu Lys Glu Lys Thr Lys Leu Gln Lys Gln Arg Glu 
                85                  90                  95


Asp Glu Leu Ile Gln Lys Ile His Lys Leu Val Gln Lys Arg Asp Phe 
            100                 105                 110


Leu Val Asp Asp Ala Glu Val Glu Arg Leu Arg Glu Gln Glu Glu Asp 
        115                 120                 125


Lys Glu Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp Lys 
    130                 135                 140


Val Thr Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu Pro 
145                 150                 155                 160


Pro Pro Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile Lys 
                165                 170                 175


Asp Cys Cys Gly Ala Thr Gln Cys Asn Ile Met 
            180                 185


<210>  8792
<211>  386
<212>  DNA
<213>  Homo sapiens

<400>  8792
gcagaagtta aaaaaatgtg cttgaggtgc cactggagaa taacaatcat agccaggatg     60

tgaagcctgt cagtttcctc agccgcaaat tcttccatgt ggggcgacct cacagagacg    120

ggatgtatgg gacggcggag tgcaaagaaa gatcagctgg acatcatctc catggcggag    180

acaaccatga tgccagagga gattgagctg gagatggcaa aaattcagcg tctccgggaa    240

gtcttggtcc gccgggagtc tgagctcagg ttcatgtgag tgttttgggg atgtggccaa    300

ggaaagaagt gtgtggagga gagaggaaaa cctaatattt gttgatcgtc tactgtgtgc    360

caggcactga gataaaggca ttatgc                                         386


<210>  8793
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  8793

Met Trp Gly Asp Leu Thr Glu Thr Gly Cys Met Gly Arg Arg Ser Ala 
1               5                   10                  15


Lys Lys Asp Gln Leu Asp Ile Ile Ser Met Ala Glu Thr Thr Met Met 
            20                  25                  30


Pro Glu Glu Ile Glu Leu Glu Met Ala Lys Ile Gln Arg Leu Arg Glu 
        35                  40                  45


Val Leu Val Arg Arg Glu Ser Glu Leu Arg Phe Met 
    50                  55                  60


<210>  8794
<211>  462
<212>  DNA
<213>  Homo sapiens

<400>  8794
ttaaatagcc atgcatccag tatctcgcag ggtggtcatg aggagtaaaa gagatcaagc     60

atattaagtg ctcagtccag tgcctgctac caccctttac agaagtagcc agaagttgga    120

ggcaatgtgt ccatcttgca ccaggccaac atccccccat gcttccgcgt ctcagccttg    180

actgcctatt gcaatcacat ggagaacttt aaagaaaatg ctggggcctg gtcttacagc    240

cagagtcttg tctagttgtt ccaaggcata gcctggtcat tgagagtctt agaagcaggt    300

aggctgatgc cccctcacct cccacggcac agacatcccc tcacctcttc gctggctgaa    360

atagaagaac cctagtgtcc atcagctgct tatagatgac tcatcttctt aatcctttct    420

tgacgaaaac ttgcttcaga tgttaataaa aagtacaaaa tc                       462


<210>  8795
<211>  387
<212>  DNA
<213>  Homo sapiens

<400>  8795
tgtgcctggc cataattttt ttatatcata catacagaaa agagcagtat tagtagttgt     60

tattgtaaga aaaatgaaaa ctaaggcagt ctagaaagcc cttggaagag agaagaataa    120

actgcgcttg aggaagttga catttgggaa gctgaggcgg gtggatcacc tgaggtcagg    180

agttcgagac cagcctggcc aacatagtga aatcccctct ctaccaaaat acaaaaattt    240

gctgggcatg gtggcaagtg cctgttatct cagctacttg ggaggctgag gcaggagaat    300

cgcctgaacc tgggaggtga ggttgcagtg agccaagatc ccgccattgc actacagcct    360

ggacgacaag agcgaaactc catctca                                        387


<210>  8796
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  8796

Asn Pro Leu Ser Thr Lys Ile Gln Lys Phe Ala Gly His Gly Gly Lys 
1               5                   10                  15


Cys Leu Leu Ser Gln Leu Leu Gly Arg Leu Arg Gln Glu Asn Arg Leu 
            20                  25                  30


Asn Leu Gly Gly Glu Val Ala Val Ser Gln Asp Pro Ala Ile Ala Leu 
        35                  40                  45


Gln Pro Gly Arg Gln Glu Arg Asn Ser Ile 
    50                  55


<210>  8797
<211>  1557
<212>  DNA
<213>  Homo sapiens

<400>  8797
ggctggcaaa gagaagggag cgtggagccg ccattttgaa catacctaga ccaggtggcc     60

ttttcctatg ggcacagctg ccagcattca cccgtaaaaa gaaaaaacca aactgcagaa    120

gcagagagag gatgagctaa tccagaagat ccacaaactg gtgcagaaga gagacttcct    180

ggtggacgat gcggaggtcg agcggttaag ggagcaagaa gaagacaagg aaatggctga    240

tttcctgaga atcaagttaa aacctctaga caaagtaacc aaatctccag ccagctcccg    300

ggcagagaag aaagcagagc ccccacctag caagcccacg gtggccaaga cggggctggc    360

actgatcaag gattgttgcg gggccaccca gtgcaacatc atgtagcccc cacgtggggt    420

gccctgggcc atggggaccc ccccccaccc tcttgtcttt atagccccca tttcaccggg    480

gcccaagagc tctccaaggc agaaggggtt gaaggcaagc ccgtgactgt caccagaggc    540

catgggcacg gcaggcgggc ctggccaccc tgtacagagt gtagcagtag ggagtctctc    600

accgtcgcat ggtcctcccc agagcatgcc gaacccagga gtctgtctca ctgtttatcc    660

aaacaccagg aaaggtcctc cctcaaaaaa gcatatctcc acttctctct agctgtatct    720

aacccaccgt gtgaatgaac tgggagaggg gcatgctccc cagctgtgtg tagtcgtgac    780

ttctcaacaa tctagcacca tgtcggacac gttccccatc caccctccta gctctgctct    840

cagagctagg cacatgggca caggtcccct cccgtctgtc ctctcccagc aactgtgccc    900

tggagggctc cacatggccc ccgtgtctct cgggcaccac ccatatagca gtcccagagg    960

gcccatctgt aaagatcgag cttgtgtgtg gtgtcgtggt cacatctccc gcttcccccc   1020

atcctgtgtc tgggcacagt tcacatcagg acagcgtcca ttgtgctctc agtctgcctc   1080

aggtgtgtgc ctggaggggg cctggactgg catggatcca gtgtgcagaa gagccagcag   1140

ggaaccggaa gctctgatgt caaggccaga gcagttgaga atgggaccca gagtagatgc   1200

tgacctgggc actccaccat tccggggcca ccacagagat gccagcagga tgccactttg   1260

ccagcccgac acacggacct ttgtaaagaa cagcaacagg caggagaggc agcgtgtgac   1320

cagattgtgt cccgtcattg ggtggcatat gttaactagc tgccaaacaa cttcaacccg   1380

tgtaattcat gtacatttgc aacagccagc ccggtacagc ctgtgtgact tctctgtatg   1440

tgtgtgtgtg tcgtgaccag cctaagtagt tagcataact caagatgctg atgtgcagtc   1500

acccatcaga gaaaataaaa atggaaacca cgttcacagc attttaaaag tttttac      1557


<210>  8798
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8798

Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp Lys Val Thr 
1               5                   10                  15


Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu Pro Pro Pro 
            20                  25                  30


Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile Lys Asp Cys 
        35                  40                  45


Cys Gly Ala Thr Gln Cys Asn Ile Met 
    50                  55


<210>  8799
<211>  1837
<212>  DNA
<213>  Homo sapiens

<400>  8799
ggctggcaaa gagaagggag cgtggagccg ccattttgaa catacctaga ccaggtggcc     60

ttttcctatg ggcacagctg ccagcattca cccgtaaaaa gaaaaaacca aactgcagaa    120

gcagagagag gatgagctaa tccagaagat ccacaaactg gtgcagaaga gagacttcct    180

ggtggacgat gcggaggtcg agcggttaag ggagcaagaa gaagacaagg aaatggctga    240

tttcctgaga atcaagttaa aacctctaga caaagtaacc aaatctccag ccagctcccg    300

ggcagagaag aaagcagagc ccccacctag caagcccacg gtggccaaga cggggctggc    360

actgatcaag gattgttgcg gggccaccca gtgcaacatc atgtagcccc cacgtggggt    420

gccctgggcc atggggaccc ccccccaccc tcttgtcttt atagccccca tttcaccggg    480

gcccaagagc tctccaaggc agaaggggtt gaaggcaagc ccgtgactgt caccagaggc    540

catgggcacg gcaggcgggc ctggccaccc tgtacagagt gtagcagtag ggagtctctc    600

accgtcgcat ggtcctcccc agagcatgcc gaacccagga gtctgtctca ctgtttatcc    660

aaacaccagg aaaggtcctc cctcaaaaaa gcatatctcc acttctctct agctgtatct    720

aacccaccgt gtgaatgaac tgggagaggg gcatgctccc cagctgtgtg tagtcgtgac    780

ttctcaacaa tctagcacca tgtcggacac gttccccatc caccctccta gctctgctct    840

cagagctagg cacatgggca caggtcccct cccgtctgtc ctctcccagc aactgtgccc    900

tggagggctc cacatggccc ccgtgtctct cgggcaccac ccatatagca gtcccagagg    960

gcccatctgt aaagatcgag cttgtgtgtg gtgtcgtggt cacatctccc gcttcccccc   1020

atcctgtgtc tgggcacagt tcacatcagg acagcgtcca ttgtgctctc agtctgcctc   1080

aggtgtgtgc ctggaggggg cctggactgg catggatcca gtgtgcagaa gagccagcag   1140

ggaaccggaa gctctgatgt caaggccaga gcagttgaga atgggaccca gagtagatgc   1200

tgacctgggc actccaccat tccggggcca ccacagagat gccagcagga tgccactttg   1260

ccagcccgac acacggacct ttgtaaagaa cagcaacagg caggagaggc agcgtgtgac   1320

cagattgtgt cccgtcattg ggtggcatat gttaactagc tgccaaacaa cttcaacccg   1380

tgtaattcat gtacatttgc aacagccagc ccggtacagc ctgtgtgact tctctgtatg   1440

tgtgtgtgtg tcgtgaccag cctaagtagt tagcataact caagatgctg atgtgcagtc   1500

acccatcaga gaaaataaaa atggaaacca cgttcacagc attttaaaag tttttacttt   1560

ttttcttgat tatggaagta atccatgtac atagtaaatc attttaaaag tacaaaaagt   1620

atgaagaagt ttgtcttaaa aaaaaaaaaa attattcctc caactagaga ccactctgat   1680

gtttcgacgt tttaaaaaag tctttttttg tgcatttttt catcgttgac atcatattgt   1740

ggtatcattt ataaccagtt ttttcctact tattatacca ccatcttcca catcattaaa   1800

agctctttgt aaacattaaa cactcttcat aaatcat                            1837


<210>  8800
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8800

Met Ala Asp Phe Leu Arg Ile Lys Leu Lys Pro Leu Asp Lys Val Thr 
1               5                   10                  15


Lys Ser Pro Ala Ser Ser Arg Ala Glu Lys Lys Ala Glu Pro Pro Pro 
            20                  25                  30


Ser Lys Pro Thr Val Ala Lys Thr Gly Leu Ala Leu Ile Lys Asp Cys 
        35                  40                  45


Cys Gly Ala Thr Gln Cys Asn Ile Met 
    50                  55


<210>  8801
<211>  1416
<212>  DNA
<213>  Homo sapiens

<400>  8801
ataagggcta tagagagatt tttacaagtc agattttttg ttccccaaat cttttaaatg     60

aagccagtga ctcccagttc tcaacacatg gccccagtca agacagaaca ccatggaaaa    120

aaccctgtaa gtattatggc actctccgaa tcctcctgaa ggcatttcct ctacagacat    180

agtgttacag gaagtgaaat gcaaatgtgc aatttttttt aaaggagctt ttaaacaaag    240

taataataat tggtgttgag aacatcagtt gccttattct aagatttcat aaggctgagt    300

ttgcacgctt ggacttcagt tctgctagca tgtaaagagt ggtggacttt aaaaccgtaa    360

gaggtatcat tacaagtcac ctggaacaga ctcaaagaac aggttctttg ggcaacagac    420

aaagaagaat caagttctgt gctgtcccgt gagtgtgtct gagtaccatt cactggagtt    480

gctgcttagg tctgggacgt gtgtgtgact cttaacaatt gctgtctgaa aatgagagag    540

aagacttcgg aagcacattg tgttcataat gtactccaca atggccagtc caattgctat    600

ctattttttt atccagaggc ttaattaaat gatgtggtaa aatgatgttt gagcattaag    660

acaatgtaat tctttatttc tgggtggaaa gatataccgg attaaattta tctgtttaaa    720

aaaatgacaa aagttatcac caaaaccccc tttcccatct tgcactgttt gttttggatt    780

gggtttgggg gaaagagatg tttttcttag ttgtctactt tgtttgaaca cttttgttgt    840

ggttcaagtg ctgttttgtg tgttgggacc aaacagttgt caataaactt tacaagcgag    900

catctatttt gagtttccca agtgagtggt tttgtctgtc tgtctgtctg tggggaggaa    960

ttacaaacca atacagttct gccatctttc attttgggtc tcctcaactt ctctcccctt   1020

ctggaaatag aattgtgagg tggagagtaa atccgtctac atcttagagg ccttttaaac   1080

tcacaccctc tggcaagaat ttaaaaggac ccagaagaga cttgagtaaa ttgcttcttg   1140

atgacatttt tttcaagttc agcaatgtta aaagctgcta aagacctttc caaacatttc   1200

acgatggcaa atttgtgcag aaaaagttga gtagccatcg tgcccctttt gagcggcgtc   1260

aggaggtctt gttaggtgtg gactggggct ggaacggtgg ctttgcattt atctttgttt   1320

gtttcccacc taggaaggtg attcagaggt gggggcctag aagacagctg tctgggggag   1380

agcagacctg tccgtagcag agggggctgc gctgat                             1416


<210>  8802
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  8802

Met Lys Pro Val Thr Pro Ser Ser Gln His Met Ala Pro Val Lys Thr 
1               5                   10                  15


Glu His His Gly Lys Asn Pro Val Ser Ile Met Ala Leu Ser Glu Ser 
            20                  25                  30


Ser 



<210>  8803
<211>  2100
<212>  DNA
<213>  Homo sapiens

<400>  8803
aaaatggaga ttccaatacc aggaaagagc aaaactctga cctctgactc cagctcgtcc     60

tgcatctcag cagctgtccc cgtgcctccc tgcccctcct cggaaacctc cgagtcactg    120

ctcagcaagg accccgtgga aagcccggcc aaaaagcaac ccaaaaatag agtcaaattg    180

gcagccaact tttccttagc acctataacc aagctttaac tcccatttgg aatatagaat    240

taggatggga aaacactgtc tgattctgca cacaaaagtg ggtttcaaaa atacatcctt    300

ttctgtgtca tgaaaacccc ccgaagccat tgacttcatc ttacctgtgt tctatcatgt    360

ttttcttttc cattgaacac agctttgagc tgaagtcttt cttttcttct tcctttttct    420

ttcttttttc aattatttga agaacttgtg gcatttgtta aagaatcctt aatatatttt    480

accaaatttt tagtaactat tatgaaatac aatggtgttc caaaagaaga aagcactaaa    540

aactcaacta gcaggaagcg gttttgcttc cattgagcca cgtcggtggt gtcatcctac    600

atgtagcata atagagtctc tcagcctttg cttactggtg tttccgacag tattaaccca    660

gtgcgtggca tgtctttgaa gcaaagcctg tcccgctagc ctgtgtgttc acacaccaaa    720

ggagaagggt aggcgagggg ttcggagtgt attttcaggt tggaatgtga aggttcctgg    780

cttccatgtg acttgtaagt gtgccttgtt ttttatttaa actatgtctg tagttgacaa    840

aagtggcttc atcacaaatt tttttaaacg tttctatgtt ggaagcatct ctgggtttct    900

tgtggcgtct ggtgtggaat ggccttcctc tctaggtgcc tgaggtgtcc gctgacgggt    960

ggcctctcac ccccctctag agaaacctga catttacaat ggattgtatt tgtccggcaa   1020

aaaaggcgga ttcattcata gagcagaaag aacctgttgg cgtaaggtct tccactagtt   1080

agatggtttc ttttggggaa atgtttatat ttggtaactt ctagaaagcc agaaaatgga   1140

ctctgatttc atagcatttt gataaaatgc cacaaaataa gggctataga gagattttta   1200

caagtcagat tttttgttcc ccaaatcttt taaatgaagc cagtgactcc cagttctcaa   1260

cacatggccc cagtcaagac agaacaccat ggaaaaaacc ctgtaagtat tatggcactc   1320

tccgaatcct cctgaaggca tttcctctac agacatagtg ttacaggaag tgaaatgcaa   1380

atgtgcaatt ttttttaaag gagcttttaa acaaagtaat aataattggt gttgagaaca   1440

tcagttgcct tattctaaga tttcataagg ctgagtttgc acgcttggac ttcagttctg   1500

ctagcatgta aagagtggtg gactttaaaa ccgtaagagg tatcattaca agtcacctgg   1560

aacagactca aagaacaggt tctttgggca acagacaaag aagaatcaag ttctgtgctg   1620

tcccgtgagt gtgtctgagt accattcact ggagttgctg cttaggtctg ggacgtgtgt   1680

gtgactctta acaattgctg tctgaaaatg agagagaaga cttcggaagc acattgtgtt   1740

cataatgtac tccacaatgg ccagtccaat tgctatctat ttttttatcc agaggcttaa   1800

ttaaatgatg tggtaaaatg atgtttgagc attaagacaa tgtaattctt tatttctggg   1860

tggaaagata taccggatta aatttatctg tttaaaaaaa tgacaaaagt tatcaccaaa   1920

accccctttc ccatcttgca ctgtttgttt tggattgggt ttgggggaaa gagatgtttt   1980

tcttagttgt ctactttgtt tgaacacttt tgttgtggtt caagtgctgt tttgtgtgtt   2040

gggaccaaac agttgtcaat aaactttaca agcgagcatc tattttgagt ttcccaagtg   2100


<210>  8804
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  8804

Met Ser Val Val Asp Lys Ser Gly Phe Ile Thr Asn Phe Phe Lys Arg 
1               5                   10                  15


Phe Tyr Val Gly Ser Ile Ser Gly Phe Leu Val Ala Ser Gly Val Glu 
            20                  25                  30


Trp Pro Ser Ser Leu Gly Ala 
        35


<210>  8805
<211>  2887
<212>  DNA
<213>  Homo sapiens

<400>  8805
tttttttttt tttttttaat accttaaata cttcttgact ctcttatctt taaggcttag     60

aaggaaaact tcaggtgtga gcccagggtg tgtgctgggg gtgggcgtgg aggtcctgtg    120

gtgtcacggc cctccttgtt tgcccagggc ccagtcacac agagcaggag cttctccgcc    180

tgaccgacga ctcccccgtc gacctcctgt gtgcgcctgt cccctcgtgc ctgccgtccc    240

ctcagctgag accagacccc gttatcctcc aatctgctga tctcattcag tttgaggagc    300

gccctcaaga gccttctgaa attatgattt taaaccaaga agaaaaaatg gagattccaa    360

taccaggaaa gagcaaaact ctgacctctg actccagctc gtcctgcatc tcagcagctg    420

tccccgtgcc tccctgcccc tcctcggaaa cctccgagtc actgctcagc aaggaccccg    480

tggaaagccc ggccaaaaag caacccaaaa atagagtcaa attggcagcc aacttttcct    540

tagcacctat aaccaagctt taactcccat ttggaatata gaattaggat gggaaaacac    600

tgtctgattc tgcacacaaa agtgggtttc aaaaatacat ccttttctgt gtcatgaaaa    660

ccccccgaag ccattgactt catcttacct gtgttctatc atgtttttct tttccattga    720

acacagcttt gagctgaagt ctttcttttc ttcttccttt ttctttcttt tttcaattat    780

ttgaagaact tgtggcattt gttaaagaat ccttaatata ttttaccaaa tttttagtaa    840

ctattatgaa atacaatggt gttccaaaag aagaaagcac taaaaactca actagcagga    900

agcggttttg cttccattga gccacgtcgg tggtgtcatc ctacatgtag cataatagag    960

tctctcagcc tttgcttact ggtgtttccg acagtattaa cccagtgcgt ggcatgtctt   1020

tgaagcaaag cctgtcccgc tagcctgtgt gttcacacac caaaggagaa gggtaggcga   1080

ggggttcgga gtgtattttc aggttggaat gtgaaggttc ctggcttcca tgtgacttgt   1140

aagtgtgcct tgttttttat ttaaactatg tctgtagttg acaaaagtgg cttcatcaca   1200

aattttttta aacgtttcta ctttggggtt ccatttagga gctttctaga aagttgagga   1260

tgtttgaagc ttcccttctg tgttccagtt tgatatgggt taggttaagg aaaaggagat   1320

ggtctcgatg tcatggattt aaagtcagca tttggattac aacacacatt attgtgtgtc   1380

gagaggcagc attggaaaga gcctgatttt ctaaaatatg catcaagtgc ataaattaca   1440

aatcagagct gagtggggag gtgcttcagc agcagcggga tcaatacgat ttccactggg   1500

aagagacagg aattctacct acacatagga aggccaaggt tgatccactt aaccttgtta   1560

ttgtaatttt aaagctggta tcggtagctg ggaagcttta tgtgtgtgta tgtcagctca   1620

gcatctttta atcgtgtctg attttactct cgttacttct cgctgttgga agcatctctg   1680

ggtttcttgt ggcgtctggt gtggaatggc cttcctctct aggtgcctga ggtgtccgct   1740

gacgggtggc ctctcacccc cctctagaga aacctgacat ttacaatgga ttgtatttgt   1800

ccggcaaaaa aggcggattc attcatagag cagaaagaac ctgttggcgt aaggtcttcc   1860

actagttaga tggtttcttt tggggaaatg tttatatttg gtaacttcta gaaagccaga   1920

aaatggactc tgatttcata gcattttgat aaaatgccac aaaataaggg ctatagagag   1980

atttttacaa gtcagatttt ttgttcccca aatcttttaa atgaagccag tgactcccag   2040

ttctcaacac atggccccag tcaagacaga acaccatgga aaaaaccctg taagtattat   2100

ggcactctcc gaatcctcct gaaggcattt cctctacaga catagtgtta caggaagtga   2160

aatgcaaatg tgcaattttt tttaaaggag cttttaaaca aagtaataat aattggtgtt   2220

gagaacatca gttgccttat tctaagattt cataaggctg agtttgcacg cttggacttc   2280

agttctgcta gcatgtaaag agtggtggac tttaaaaccg taagaggtat cattacaagt   2340

cacctggaac agactcaaag aacaggttct ttgggcaaca gacaaagaag aatcaagttc   2400

tgtgctgtcc cgtgagtgtg tctgagtacc attcactgga gttgctgctt aggtctggga   2460

cgtgtgtgtg actcttaaca attgctgtct gaaaatgaga gagaagactt cggaagcaca   2520

ttgtgttcat aatgtactcc acaatggcca gtccaattgc tatctatttt tttatccaga   2580

ggcttaatta aatgatgtgg taaaatgatg tttgagcatt aagacaatgt aattctttat   2640

ttctgggtgg aaagatatac cggattaaat ttatctgttt aaaaaaatga caaaagttat   2700

caccaaaacc ccctttccca tcttgcactg tttgttttgg attgggtttg ggggaaagag   2760

atgtttttct tagttgtcta ctttgtttga acacttttgt tgtggttcaa gtgctgtttt   2820

gtgtgttggg accaaacagt tgtcaataaa ctttacaagc gagcatctat tttgagtttc   2880

ccaagtg                                                             2887


<210>  8806
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8806

Met Ile Leu Asn Gln Glu Glu Lys Met Glu Ile Pro Ile Pro Gly Lys 
1               5                   10                  15


Ser Lys Thr Leu Thr Ser Asp Ser Ser Ser Ser Cys Ile Ser Ala Ala 
            20                  25                  30


Val Pro Val Pro Pro Cys Pro Ser Ser Glu Thr Ser Glu Ser Leu Leu 
        35                  40                  45


Ser Lys Asp Pro Val Glu Ser Pro Ala Lys Lys Gln Pro Lys Asn Arg 
    50                  55                  60


Val Lys Leu Ala Ala Asn Phe Ser Leu Ala Pro Ile Thr Lys Leu 
65                  70                  75


<210>  8807
<211>  2866
<212>  DNA
<213>  Homo sapiens

<400>  8807
cctcggaact caagcttgga gctgacggca gtggcttaga aggaaaactt caggtgtgag     60

cccagggtgt gtgctggggg tgggcgtgga ggtcctgtgg tgtcacggcc ctccttgttt    120

gcccagggcc cagtcacaca gagcaggagc ttctccgcct gaccgacgac tcccccgtcg    180

acctcctgtg tgcgcctgtc ccctcgtgcc tgccgtcccc tcagctgaga ccagaccccg    240

ttatcctcca atctgctgat ctcattcagt ttgaggagcg ccctcaagag ccttctgaaa    300

ttatgatttt aaaccaagaa gaaaaaatgg agattccaat accaggaaag agcaaaactc    360

tgacctctga ctccagctcg tcctgcatct cagcagctgt ccccgtgcct ccctgcccct    420

cctcggaaac ctccgagtca ctgctcagca aggaccccgt ggaaagcccg gccaaaaagc    480

aacccaaaaa tagagtcaaa ttggcagcca acttttcctt agcacctata accaagcttt    540

aactcccatt tggaatatag aattaggatg ggaaaacact gtctgattct gcacacaaaa    600

gtgggtttca aaaatacatc cttttctgtg tcatgaaaac cccccgaagc cattgacttc    660

atcttacctg tgttctatca tgtttttctt ttccattgaa cacagctttg agctgaagtc    720

tttcttttct tcttcctttt tctttctttt ttcaattatt tgaagaactt gtggcatttg    780

ttaaagaatc cttaatatat tttaccaaat ttttagtaac tattatgaaa tacaatggtg    840

ttccaaaaga agaaagcact aaaaactcaa ctagcaggaa gcggttttgc ttccattgag    900

ccacgtcggt ggtgtcatcc tacatgtagc ataatagagt ctctcagcct ttgcttactg    960

gtgtttccga cagtattaac ccagtgcgtg gcatgtcttt gaagcaaagc ctgtcccgct   1020

agcctgtgtg ttcacacacc aaaggagaag ggtaggcgag gggttcggag tgtattttca   1080

ggttggaatg tgaaggttcc tggcttccat gtgacttgta agtgtgcctt gttttttatt   1140

taaactatgt ctgtagttga caaaagtggc ttcatcacaa atttttttaa acgtttctac   1200

tttggggttc catttaggag ctttctagaa agttgaggat gtttgaagct tcccttctgt   1260

gttccagttt gatatgggtt aggttaagga aaaggagatg gtctcgatgt catggattta   1320

aagtcagcat ttggattaca acacacatta ttgtgtgtcg agaggcagca ttggaaagag   1380

cctgattttc taaaatatgc atcaagtgca taaattacaa atcagagctg agtggggagg   1440

tgcttcagca gcagcgggat caatacgatt tccactggga agagacagga attctaccta   1500

cacataggaa ggccaaggtt gatccactta accttgttat tgtaatttta aagctggtat   1560

cggtagctgg gaagctttat gtgtgtgtat gtcagctcag catcttttaa tcgtgtctga   1620

ttttactctc gttacttctc gctgttggaa gcatctctgg gtttcttgtg gcgtctggtg   1680

tggaatggcc ttcctctcta ggtgcctgag gtgtccgctg acgggtggcc tctcaccccc   1740

ctctagagaa acctgacatt tacaatggat tgtatttgtc cggcaaaaaa ggcggattca   1800

ttcatagagc agaaagaacc tgttggcgta aggtcttcca ctagttagat ggtttctttt   1860

ggggaaatgt ttatatttgg taacttctag aaagccagaa aatggactct gatttcatag   1920

cattttgata aaatgccaca aaataagggc tatagagaga tttttacaag tcagattttt   1980

tgttccccaa atcttttaaa tgaagccagt gactcccagt tctcaacaca tggccccagt   2040

caagacagaa caccatggaa aaaaccctgt aagtattatg gcactctccg aatcctcctg   2100

aaggcatttc ctctacagac atagtgttac aggaagtgaa atgcaaatgt gcaatttttt   2160

ttaaaggagc ttttaaacaa agtaataata attggtgttg agaacatcag ttgccttatt   2220

ctaagatttc ataaggctga gtttgcacgc ttggacttca gttctgctag catgtaaaga   2280

gtggtggact ttaaaaccgt aagaggtatc attacaagtc acctggaaca gactcaaaga   2340

acaggttctt tgggcaacag acaaagaaga atcaagttct gtgctgtccc gtgagtgtgt   2400

ctgagtacca ttcactggag ttgctgctta ggtctgggac gtgtgtgtga ctcttaacaa   2460

ttgctgtctg aaaatgagag agaagacttc ggaagcacat tgtgttcata atgtactcca   2520

caatggccag tccaattgct atctattttt ttatccagag gcttaattaa atgatgtggt   2580

aaaatgatgt ttgagcatta agacaatgta attctttatt tctgggtgga aagatatacc   2640

ggattaaatt tatctgttta aaaaaatgac aaaagttatc accaaaaccc cctttcccat   2700

cttgcactgt ttgttttgga ttgggtttgg gggaaagaga tgtttttctt agttgtctac   2760

tttgtttgaa cacttttgtt gtggttcaag tgctgttttg tgtgttggga ccaaacagtt   2820

gtcaataaac tttacaagcg agcatctatt ttgagtttcc caagtg                  2866


<210>  8808
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8808

Met Ile Leu Asn Gln Glu Glu Lys Met Glu Ile Pro Ile Pro Gly Lys 
1               5                   10                  15


Ser Lys Thr Leu Thr Ser Asp Ser Ser Ser Ser Cys Ile Ser Ala Ala 
            20                  25                  30


Val Pro Val Pro Pro Cys Pro Ser Ser Glu Thr Ser Glu Ser Leu Leu 
        35                  40                  45


Ser Lys Asp Pro Val Glu Ser Pro Ala Lys Lys Gln Pro Lys Asn Arg 
    50                  55                  60


Val Lys Leu Ala Ala Asn Phe Ser Leu Ala Pro Ile Thr Lys Leu 
65                  70                  75


<210>  8809
<211>  4462
<212>  DNA
<213>  Homo sapiens

<400>  8809
tttgcaaaga atgtgcggtc tttacttcat acttaccact accagcagat tttccttcat     60

gagttttcca tggcctatac caagtatgtc ggagaaactc tgcagcccaa gacctacggc    120

cacagcagcg tggaggagct cttgggagca attccacagg tgggcatttt tctcagcttc    180

cgggagagca tcttctgaac agccacaggc taactgtcct gaacagaaaa ataaaatgct    240

gccagaataa tggaacggca ggcattttga attgatcctt tcaaaacata ctgttggtct    300

aaagtaaatg attttagcat ttctccttga ttctttctgt aaacctttat taaatcccta    360

tatgccaggt gagtaagttt caggctgtaa ctctagaaag gtgttggtta atgggagagt    420

caagaccccc aagcaggcaa ctagtcaggg cggtcagggc agtgggcgcg ctgaggaggg    480

ccgtgtcagg gcccacttcc caagcctggg gagcctgttg caaaaccttc aaggatgtgc    540

ctgagggaag cacgtgacaa ggaggggaga gagcattctg ggcaaagggg atgatgacat    600

gagcagatgc agggttgtga caagtggcat ggagtgtcga gaggctaaga gggagctgag    660

agctcggtta gggagggcgt ggctcctcca ggtaaggagg gaggactgtg ttggagagag    720

ctggagccca ggtttgcatt tgaaaagcac cccagtggtg ctgtccatgg tagagccgag    780

agaagcaggc atggagaagg gaactgggct aggatcctgg ccactgcaga ggtctgggtc    840

agtgttagat ggagggattg agccagagta aaaatagtag aatagaggaa gtaggaagga    900

cccaggcaaa gcttgcctgg gagctgagat cagtgacctg gcgacggtgt gcacatgtag    960

ggggcctggg agcctagctc cactactacc actctgcttg gctgagatgg agagcggcac   1020

catcagggag aggactttaa gatgctgata atgaacttag tttaaagggt ctgagagatt   1080

gctcttaatt cttttaggtg gttgttcagt ttctgcaaaa aaatggcaaa gagctctcat   1140

gtgagaacta ccttaattta tatgccaaag ctggtgtttg gaagacagtc tttttaagaa   1200

ttataaagga tatttctgaa actgtgtctc atgatttttg aactactctg ctttttatag   1260

gggtatgttt ctgtcagctt ctgttgcttt aaaagctaag gagagagtag agaaacatgc   1320

ttcttggcag taactcagct cctaaattct agcctaaggc aggctccgta ggtcacactc   1380

ttcctgaatg ttagggcttc tgtcccctcc ttttccgctg cttaaccagt agtatgtctt   1440

gtgtgcaggt ggtctggata aaaggacatg gtcataagag aattgtagtg ttaaaaaatg   1500

acatgaaaag taagtaagca cccatcccct ccccccttaa aaaatcacgg ttctctcact   1560

gacatttctc tctgacgggt gctctttgtc ctgtaggtcg tttgagttca ctcagtctct   1620

cccctgccaa tcatgaaaac cagccctcgg agggcgagcg catcctggag gtgcccgaat   1680

cgcacacagc ctcggaactc aagcttggag ctgacggcag tgggcccagt cacacagagc   1740

aggagcttct ccgcctgacc gacgactccc ccgtcgacct cctgtgtgcg cctgtcccct   1800

cgtgcctgcc gtcccctcag ctgagaccag accccgttat cctccaatct gctgatctca   1860

ttcagtttga ggagcgccct caagagcctt ctgaaattat gattttaaac caagaagaaa   1920

aaatggagat tccaatacca ggaaagagca aaactctgac ctctgactcc agctcgtcct   1980

gcatctcagc agctgtcccc gtgcctccct gcccctcctc ggaaacctcc gagtcactgc   2040

tcagcaagga ccccgtggaa agcccggcca aaaagcaacc caaaaataga gtcaaattgg   2100

cagccaactt ttccttagca cctataacca agctttaact cccatttgga atatagaatt   2160

aggatgggaa aacactgtct gattctgcac acaaaagtgg gtttcaaaaa tacatccttt   2220

tctgtgtcat gaaaaccccc cgaagccatt gacttcatct tacctgtgtt ctatcatgtt   2280

tttcttttcc attgaacaca gctttgagct gaagtctttc ttttcttctt cctttttctt   2340

tcttttttca attatttgaa gaacttgtgg catttgttaa agaatcctta atatatttta   2400

ccaaattttt agtaactatt atgaaataca atggtgttcc aaaagaagaa agcactaaaa   2460

actcaactag caggaagcgg ttttgcttcc attgagccac gtcggtggtg tcatcctaca   2520

tgtagcataa tagagtctct cagcctttgc ttactggtgt ttccgacagt attaacccag   2580

tgcgtggcat gtctttgaag caaagcctgt cccgctagcc tgtgtgttca cacaccaaag   2640

gagaagggta ggcgaggggt tcggagtgta ttttcaggtt ggaatgtgaa ggttcctggc   2700

ttccatgtga cttgtaagtg tgccttgttt tttatttaaa ctatgtctgt agttgacaaa   2760

agtggcttca tcacaaattt ttttaaacgt ttctactttg gggttccatt taggagcttt   2820

ctagaaagtt gaggatgttt gaagcttccc ttctgtgttc cagtttgata tgggttaggt   2880

taaggaaaag gagatggtct cgatgtcatg gatttaaagt cagcatttgg attacaacac   2940

acattattgt gtgtcgagag gcagcattgg aaagagcctg attttctaaa atatgcatca   3000

agtgcataaa ttacaaatca gagctgagtg gggaggtgct tcagcagcag cgggatcaat   3060

acgatttcca ctgggaagag acaggaattc tacctacaca taggaaggcc aaggttgatc   3120

cacttaacct tgttattgta attttaaagc tggtatcggt agctgggaag ctttatgtgt   3180

gtgtatgtca gctcagcatc ttttaatcgt gtctgatttt actctcgtta cttctcgctg   3240

ttggaagcat ctctgggttt cttgtggcgt ctggtgtgga atggccttcc tctctaggtg   3300

cctgaggtgt ccgctgacgg gtggcctctc acccccctct agagaaacct gacatttaca   3360

atggattgta tttgtccggc aaaaaaggcg gattcattca tagagcagaa agaacctgtt   3420

ggcgtaaggt cttccactag ttagatggtt tcttttgggg aaatgtttat atttggtaac   3480

ttctagaaag ccagaaaatg gactctgatt tcatagcatt ttgataaaat gccacaaaat   3540

aagggctata gagagatttt tacaagtcag attttttgtt ccccaaatct tttaaatgaa   3600

gccagtgact cccagttctc aacacatggc cccagtcaag acagaacacc atggaaaaaa   3660

ccctgtaagt attatggcac tctccgaatc ctcctgaagg catttcctct acagacatag   3720

tgttacagga agtgaaatgc aaatgtgcaa ttttttttaa aggagctttt aaacaaagta   3780

ataataattg gtgttgagaa catcagttgc cttattctaa gatttcataa ggctgagttt   3840

gcacgcttgg acttcagttc tgctagcatg taaagagtgg tggactttaa aaccgtaaga   3900

ggtatcatta caagtcacct ggaacagact caaagaacag gttctttggg caacagacaa   3960

agaagaatca agttctgtgc tgtcccgtga gtgtgtctga gtaccattca ctggagttgc   4020

tgcttaggtc tgggacgtgt gtgtgactct taacaattgc tgtctgaaaa tgagagagaa   4080

gacttcggaa gcacattgtg ttcataatgt actccacaat ggccagtcca attgctatct   4140

atttttttat ccagaggctt aattaaatga tgtggtaaaa tgatgtttga gcattaagac   4200

aatgtaattc tttatttctg ggtggaaaga tataccggat taaatttatc tgtttaaaaa   4260

aatgacaaaa gttatcacca aaaccccctt tcccatcttg cactgtttgt tttggattgg   4320

gtttggggga aagagatgtt tttcttagtt gtctactttg tttgaacact tttgttgtgg   4380

ttcaagtgct gttttgtgtg ttgggaccaa acagttgtca ataaacttta caagcgagca   4440

tctattttga gtttcccaag tg                                            4462


<210>  8810
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8810

Met Lys Thr Ser Pro Arg Arg Ala Ser Ala Ser Trp Arg Cys Pro Asn 
1               5                   10                  15


Arg Thr Gln Pro Arg Asn Ser Ser Leu Glu Leu Thr Ala Val Gly Pro 
            20                  25                  30


Val Thr Gln Ser Arg Ser Phe Ser Ala 
        35                  40


<210>  8811
<211>  2083
<212>  DNA
<213>  Homo sapiens

<400>  8811
aaaatggaga ttccaatacc aggaaagagc aaaactctga cctctgactc cagctcgtcc     60

tgcatctcag cagctgtccc cgtgcctccc tgcccctcct cggaaacctc cgagtcactg    120

ctcagcaagg accccgtgga aagcccggcc aaaaagcaac ccaaaaatag agtcaaattg    180

gcagccaact tttccttagc acctataacc aagctttaac tcccatttgg aatatagaat    240

taggatggga aaacactgtc tgattctgca cacaaaagtg ggtttcaaaa atacatcctt    300

ttctgtgtca tgaaaacccc ccgaagccat tgacttcatc ttacctgtgt tctatcatgt    360

ttttcttttc cattgaacac agctttgagc tgaagtcttt cttttcttct tcctttttct    420

ttcttttttc aattatttga agaacttgtg gcatttgtta aagaatcctt aatatatttt    480

accaaatttt tagtaactat tatgaaatac aatggtgttc caaaagaaga aagcactaaa    540

aactcaacta gcaggaagcg gttttgcttc cattgagcca cgtcggtggt gtcatcctac    600

atgtagcata atagagtctc tcagcctttg cttactggtg tttccgacag tattaaccca    660

gtgcgtggca tgtctttgaa gcaaagcctg tcccgctagc ctgtgtgttc acacaccaaa    720

ggagaagggt aggcgagggg ttcggagtgt attttcaggt tggaatgtga aggttcctgg    780

cttccatgtg acttgtaagt gtgccttgtt ttttatttaa actatgtctg tagttgacaa    840

aagtggcttc atcacaaatt tttttaaacg tttctatgtt ggaagcatct ctgggtttct    900

tgtggcgtct ggtgtggaat ggccttcctc tctaggtgcc tgaggtgtcc gctgacgggt    960

ggcctctcac ccccctctag agaaacctga catttacaat ggattgtatt tgtccggcaa   1020

aaaaggcgga ttcattcata gagcagaaag aacctgttgg cgtaaggtct tccactagtt   1080

agatggtttc ttttggggaa atgtttatat ttggtaactt ctagaaagcc agaaaatgga   1140

ctctgatttc atagcatttt gataaaatgc cacaaaataa gggctataga gagattttta   1200

caagtcagat tttttgttcc ccaaatcttt taaatgaagc cagtgactcc cagttctcaa   1260

cacatggccc cagtcaagac agaacaccat ggaaaaaacc ctgtaagtat tatggcactc   1320

tccgaatcct cctgaaggca tttcctctac agacatagtg ttacaggaag tgaaatgcaa   1380

atgtgcaatt ttttttaaag gagcttttaa acaaagtaat aataattggt gttgagaaca   1440

tcagttgcct tattctaaga tttcataagg ctgagtttgc acgcttggac ttcagttctg   1500

ctagcatgta aagagtggtg gactttaaaa ccgtaagagg tatcattaca agtcacctgg   1560

aacagactca aagaacaggt tctttgggca acagacaaag aagaatcaag ttctgtgctg   1620

tcccgtgagt gtgtctgagt accattcact ggagttgctg cttaggtctg ggacgtgtgt   1680

gtgactctta acaattgctg tctgaaaatg agagagaaga cttcggaagc acattgtgtt   1740

cataatgtac tccacaatgg ccagtccaat tgctatctat ttttttatcc agaggcttaa   1800

ttaaatgatg tggtaaaatg atgtttgagc attaagacaa tgtaattctt tatttctggg   1860

tggaaagata taccggatta aatttatctg tttaaaaaaa tgacaaaagt tatcaccaaa   1920

accccctttc ccatcttgca ctgtttgttt tggattgggt ttgggggaaa gagatgtttt   1980

tcttagttgt ctactttgtt tgaacacttt tgttgtggtt caagtgctgt tttgtgtgtt   2040

gggaccaaac agttgtcaat aaactttaca agcgagcatc tat                     2083


<210>  8812
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  8812

Met Ser Val Val Asp Lys Ser Gly Phe Ile Thr Asn Phe Phe Lys Arg 
1               5                   10                  15


Phe Tyr Val Gly Ser Ile Ser Gly Phe Leu Val Ala Ser Gly Val Glu 
            20                  25                  30


Trp Pro Ser Ser Leu Gly Ala 
        35


<210>  8813
<211>  2870
<212>  DNA
<213>  Homo sapiens

<400>  8813
tttttttttt tttttttaat accttaaata cttcttgact ctcttatctt taaggcttag     60

aaggaaaact tcaggtgtga gcccagggtg tgtgctgggg gtgggcgtgg aggtcctgtg    120

gtgtcacggc cctccttgtt tgcccagggc ccagtcacac agagcaggag cttctccgcc    180

tgaccgacga ctcccccgtc gacctcctgt gtgcgcctgt cccctcgtgc ctgccgtccc    240

ctcagctgag accagacccc gttatcctcc aatctgctga tctcattcag tttgaggagc    300

gccctcaaga gccttctgaa attatgattt taaaccaaga agaaaaaatg gagattccaa    360

taccaggaaa gagcaaaact ctgacctctg actccagctc gtcctgcatc tcagcagctg    420

tccccgtgcc tccctgcccc tcctcggaaa cctccgagtc actgctcagc aaggaccccg    480

tggaaagccc ggccaaaaag caacccaaaa atagagtcaa attggcagcc aacttttcct    540

tagcacctat aaccaagctt taactcccat ttggaatata gaattaggat gggaaaacac    600

tgtctgattc tgcacacaaa agtgggtttc aaaaatacat ccttttctgt gtcatgaaaa    660

ccccccgaag ccattgactt catcttacct gtgttctatc atgtttttct tttccattga    720

acacagcttt gagctgaagt ctttcttttc ttcttccttt ttctttcttt tttcaattat    780

ttgaagaact tgtggcattt gttaaagaat ccttaatata ttttaccaaa tttttagtaa    840

ctattatgaa atacaatggt gttccaaaag aagaaagcac taaaaactca actagcagga    900

agcggttttg cttccattga gccacgtcgg tggtgtcatc ctacatgtag cataatagag    960

tctctcagcc tttgcttact ggtgtttccg acagtattaa cccagtgcgt ggcatgtctt   1020

tgaagcaaag cctgtcccgc tagcctgtgt gttcacacac caaaggagaa gggtaggcga   1080

ggggttcgga gtgtattttc aggttggaat gtgaaggttc ctggcttcca tgtgacttgt   1140

aagtgtgcct tgttttttat ttaaactatg tctgtagttg acaaaagtgg cttcatcaca   1200

aattttttta aacgtttcta ctttggggtt ccatttagga gctttctaga aagttgagga   1260

tgtttgaagc ttcccttctg tgttccagtt tgatatgggt taggttaagg aaaaggagat   1320

ggtctcgatg tcatggattt aaagtcagca tttggattac aacacacatt attgtgtgtc   1380

gagaggcagc attggaaaga gcctgatttt ctaaaatatg catcaagtgc ataaattaca   1440

aatcagagct gagtggggag gtgcttcagc agcagcggga tcaatacgat ttccactggg   1500

aagagacagg aattctacct acacatagga aggccaaggt tgatccactt aaccttgtta   1560

ttgtaatttt aaagctggta tcggtagctg ggaagcttta tgtgtgtgta tgtcagctca   1620

gcatctttta atcgtgtctg attttactct cgttacttct cgctgttgga agcatctctg   1680

ggtttcttgt ggcgtctggt gtggaatggc cttcctctct aggtgcctga ggtgtccgct   1740

gacgggtggc ctctcacccc cctctagaga aacctgacat ttacaatgga ttgtatttgt   1800

ccggcaaaaa aggcggattc attcatagag cagaaagaac ctgttggcgt aaggtcttcc   1860

actagttaga tggtttcttt tggggaaatg tttatatttg gtaacttcta gaaagccaga   1920

aaatggactc tgatttcata gcattttgat aaaatgccac aaaataaggg ctatagagag   1980

atttttacaa gtcagatttt ttgttcccca aatcttttaa atgaagccag tgactcccag   2040

ttctcaacac atggccccag tcaagacaga acaccatgga aaaaaccctg taagtattat   2100

ggcactctcc gaatcctcct gaaggcattt cctctacaga catagtgtta caggaagtga   2160

aatgcaaatg tgcaattttt tttaaaggag cttttaaaca aagtaataat aattggtgtt   2220

gagaacatca gttgccttat tctaagattt cataaggctg agtttgcacg cttggacttc   2280

agttctgcta gcatgtaaag agtggtggac tttaaaaccg taagaggtat cattacaagt   2340

cacctggaac agactcaaag aacaggttct ttgggcaaca gacaaagaag aatcaagttc   2400

tgtgctgtcc cgtgagtgtg tctgagtacc attcactgga gttgctgctt aggtctggga   2460

cgtgtgtgtg actcttaaca attgctgtct gaaaatgaga gagaagactt cggaagcaca   2520

ttgtgttcat aatgtactcc acaatggcca gtccaattgc tatctatttt tttatccaga   2580

ggcttaatta aatgatgtgg taaaatgatg tttgagcatt aagacaatgt aattctttat   2640

ttctgggtgg aaagatatac cggattaaat ttatctgttt aaaaaaatga caaaagttat   2700

caccaaaacc ccctttccca tcttgcactg tttgttttgg attgggtttg ggggaaagag   2760

atgtttttct tagttgtcta ctttgtttga acacttttgt tgtggttcaa gtgctgtttt   2820

gtgtgttggg accaaacagt tgtcaataaa ctttacaagc gagcatctat              2870


<210>  8814
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8814

Met Ile Leu Asn Gln Glu Glu Lys Met Glu Ile Pro Ile Pro Gly Lys 
1               5                   10                  15


Ser Lys Thr Leu Thr Ser Asp Ser Ser Ser Ser Cys Ile Ser Ala Ala 
            20                  25                  30


Val Pro Val Pro Pro Cys Pro Ser Ser Glu Thr Ser Glu Ser Leu Leu 
        35                  40                  45


Ser Lys Asp Pro Val Glu Ser Pro Ala Lys Lys Gln Pro Lys Asn Arg 
    50                  55                  60


Val Lys Leu Ala Ala Asn Phe Ser Leu Ala Pro Ile Thr Lys Leu 
65                  70                  75


<210>  8815
<211>  2849
<212>  DNA
<213>  Homo sapiens

<400>  8815
cctcggaact caagcttgga gctgacggca gtggcttaga aggaaaactt caggtgtgag     60

cccagggtgt gtgctggggg tgggcgtgga ggtcctgtgg tgtcacggcc ctccttgttt    120

gcccagggcc cagtcacaca gagcaggagc ttctccgcct gaccgacgac tcccccgtcg    180

acctcctgtg tgcgcctgtc ccctcgtgcc tgccgtcccc tcagctgaga ccagaccccg    240

ttatcctcca atctgctgat ctcattcagt ttgaggagcg ccctcaagag ccttctgaaa    300

ttatgatttt aaaccaagaa gaaaaaatgg agattccaat accaggaaag agcaaaactc    360

tgacctctga ctccagctcg tcctgcatct cagcagctgt ccccgtgcct ccctgcccct    420

cctcggaaac ctccgagtca ctgctcagca aggaccccgt ggaaagcccg gccaaaaagc    480

aacccaaaaa tagagtcaaa ttggcagcca acttttcctt agcacctata accaagcttt    540

aactcccatt tggaatatag aattaggatg ggaaaacact gtctgattct gcacacaaaa    600

gtgggtttca aaaatacatc cttttctgtg tcatgaaaac cccccgaagc cattgacttc    660

atcttacctg tgttctatca tgtttttctt ttccattgaa cacagctttg agctgaagtc    720

tttcttttct tcttcctttt tctttctttt ttcaattatt tgaagaactt gtggcatttg    780

ttaaagaatc cttaatatat tttaccaaat ttttagtaac tattatgaaa tacaatggtg    840

ttccaaaaga agaaagcact aaaaactcaa ctagcaggaa gcggttttgc ttccattgag    900

ccacgtcggt ggtgtcatcc tacatgtagc ataatagagt ctctcagcct ttgcttactg    960

gtgtttccga cagtattaac ccagtgcgtg gcatgtcttt gaagcaaagc ctgtcccgct   1020

agcctgtgtg ttcacacacc aaaggagaag ggtaggcgag gggttcggag tgtattttca   1080

ggttggaatg tgaaggttcc tggcttccat gtgacttgta agtgtgcctt gttttttatt   1140

taaactatgt ctgtagttga caaaagtggc ttcatcacaa atttttttaa acgtttctac   1200

tttggggttc catttaggag ctttctagaa agttgaggat gtttgaagct tcccttctgt   1260

gttccagttt gatatgggtt aggttaagga aaaggagatg gtctcgatgt catggattta   1320

aagtcagcat ttggattaca acacacatta ttgtgtgtcg agaggcagca ttggaaagag   1380

cctgattttc taaaatatgc atcaagtgca taaattacaa atcagagctg agtggggagg   1440

tgcttcagca gcagcgggat caatacgatt tccactggga agagacagga attctaccta   1500

cacataggaa ggccaaggtt gatccactta accttgttat tgtaatttta aagctggtat   1560

cggtagctgg gaagctttat gtgtgtgtat gtcagctcag catcttttaa tcgtgtctga   1620

ttttactctc gttacttctc gctgttggaa gcatctctgg gtttcttgtg gcgtctggtg   1680

tggaatggcc ttcctctcta ggtgcctgag gtgtccgctg acgggtggcc tctcaccccc   1740

ctctagagaa acctgacatt tacaatggat tgtatttgtc cggcaaaaaa ggcggattca   1800

ttcatagagc agaaagaacc tgttggcgta aggtcttcca ctagttagat ggtttctttt   1860

ggggaaatgt ttatatttgg taacttctag aaagccagaa aatggactct gatttcatag   1920

cattttgata aaatgccaca aaataagggc tatagagaga tttttacaag tcagattttt   1980

tgttccccaa atcttttaaa tgaagccagt gactcccagt tctcaacaca tggccccagt   2040

caagacagaa caccatggaa aaaaccctgt aagtattatg gcactctccg aatcctcctg   2100

aaggcatttc ctctacagac atagtgttac aggaagtgaa atgcaaatgt gcaatttttt   2160

ttaaaggagc ttttaaacaa agtaataata attggtgttg agaacatcag ttgccttatt   2220

ctaagatttc ataaggctga gtttgcacgc ttggacttca gttctgctag catgtaaaga   2280

gtggtggact ttaaaaccgt aagaggtatc attacaagtc acctggaaca gactcaaaga   2340

acaggttctt tgggcaacag acaaagaaga atcaagttct gtgctgtccc gtgagtgtgt   2400

ctgagtacca ttcactggag ttgctgctta ggtctgggac gtgtgtgtga ctcttaacaa   2460

ttgctgtctg aaaatgagag agaagacttc ggaagcacat tgtgttcata atgtactcca   2520

caatggccag tccaattgct atctattttt ttatccagag gcttaattaa atgatgtggt   2580

aaaatgatgt ttgagcatta agacaatgta attctttatt tctgggtgga aagatatacc   2640

ggattaaatt tatctgttta aaaaaatgac aaaagttatc accaaaaccc cctttcccat   2700

cttgcactgt ttgttttgga ttgggtttgg gggaaagaga tgtttttctt agttgtctac   2760

tttgtttgaa cacttttgtt gtggttcaag tgctgttttg tgtgttggga ccaaacagtt   2820

gtcaataaac tttacaagcg agcatctat                                     2849


<210>  8816
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  8816

Met Ile Leu Asn Gln Glu Glu Lys Met Glu Ile Pro Ile Pro Gly Lys 
1               5                   10                  15


Ser Lys Thr Leu Thr Ser Asp Ser Ser Ser Ser Cys Ile Ser Ala Ala 
            20                  25                  30


Val Pro Val Pro Pro Cys Pro Ser Ser Glu Thr Ser Glu Ser Leu Leu 
        35                  40                  45


Ser Lys Asp Pro Val Glu Ser Pro Ala Lys Lys Gln Pro Lys Asn Arg 
    50                  55                  60


Val Lys Leu Ala Ala Asn Phe Ser Leu Ala Pro Ile Thr Lys Leu 
65                  70                  75


<210>  8817
<211>  4445
<212>  DNA
<213>  Homo sapiens

<400>  8817
tttgcaaaga atgtgcggtc tttacttcat acttaccact accagcagat tttccttcat     60

gagttttcca tggcctatac caagtatgtc ggagaaactc tgcagcccaa gacctacggc    120

cacagcagcg tggaggagct cttgggagca attccacagg tgggcatttt tctcagcttc    180

cgggagagca tcttctgaac agccacaggc taactgtcct gaacagaaaa ataaaatgct    240

gccagaataa tggaacggca ggcattttga attgatcctt tcaaaacata ctgttggtct    300

aaagtaaatg attttagcat ttctccttga ttctttctgt aaacctttat taaatcccta    360

tatgccaggt gagtaagttt caggctgtaa ctctagaaag gtgttggtta atgggagagt    420

caagaccccc aagcaggcaa ctagtcaggg cggtcagggc agtgggcgcg ctgaggaggg    480

ccgtgtcagg gcccacttcc caagcctggg gagcctgttg caaaaccttc aaggatgtgc    540

ctgagggaag cacgtgacaa ggaggggaga gagcattctg ggcaaagggg atgatgacat    600

gagcagatgc agggttgtga caagtggcat ggagtgtcga gaggctaaga gggagctgag    660

agctcggtta gggagggcgt ggctcctcca ggtaaggagg gaggactgtg ttggagagag    720

ctggagccca ggtttgcatt tgaaaagcac cccagtggtg ctgtccatgg tagagccgag    780

agaagcaggc atggagaagg gaactgggct aggatcctgg ccactgcaga ggtctgggtc    840

agtgttagat ggagggattg agccagagta aaaatagtag aatagaggaa gtaggaagga    900

cccaggcaaa gcttgcctgg gagctgagat cagtgacctg gcgacggtgt gcacatgtag    960

ggggcctggg agcctagctc cactactacc actctgcttg gctgagatgg agagcggcac   1020

catcagggag aggactttaa gatgctgata atgaacttag tttaaagggt ctgagagatt   1080

gctcttaatt cttttaggtg gttgttcagt ttctgcaaaa aaatggcaaa gagctctcat   1140

gtgagaacta ccttaattta tatgccaaag ctggtgtttg gaagacagtc tttttaagaa   1200

ttataaagga tatttctgaa actgtgtctc atgatttttg aactactctg ctttttatag   1260

gggtatgttt ctgtcagctt ctgttgcttt aaaagctaag gagagagtag agaaacatgc   1320

ttcttggcag taactcagct cctaaattct agcctaaggc aggctccgta ggtcacactc   1380

ttcctgaatg ttagggcttc tgtcccctcc ttttccgctg cttaaccagt agtatgtctt   1440

gtgtgcaggt ggtctggata aaaggacatg gtcataagag aattgtagtg ttaaaaaatg   1500

acatgaaaag taagtaagca cccatcccct ccccccttaa aaaatcacgg ttctctcact   1560

gacatttctc tctgacgggt gctctttgtc ctgtaggtcg tttgagttca ctcagtctct   1620

cccctgccaa tcatgaaaac cagccctcgg agggcgagcg catcctggag gtgcccgaat   1680

cgcacacagc ctcggaactc aagcttggag ctgacggcag tgggcccagt cacacagagc   1740

aggagcttct ccgcctgacc gacgactccc ccgtcgacct cctgtgtgcg cctgtcccct   1800

cgtgcctgcc gtcccctcag ctgagaccag accccgttat cctccaatct gctgatctca   1860

ttcagtttga ggagcgccct caagagcctt ctgaaattat gattttaaac caagaagaaa   1920

aaatggagat tccaatacca ggaaagagca aaactctgac ctctgactcc agctcgtcct   1980

gcatctcagc agctgtcccc gtgcctccct gcccctcctc ggaaacctcc gagtcactgc   2040

tcagcaagga ccccgtggaa agcccggcca aaaagcaacc caaaaataga gtcaaattgg   2100

cagccaactt ttccttagca cctataacca agctttaact cccatttgga atatagaatt   2160

aggatgggaa aacactgtct gattctgcac acaaaagtgg gtttcaaaaa tacatccttt   2220

tctgtgtcat gaaaaccccc cgaagccatt gacttcatct tacctgtgtt ctatcatgtt   2280

tttcttttcc attgaacaca gctttgagct gaagtctttc ttttcttctt cctttttctt   2340

tcttttttca attatttgaa gaacttgtgg catttgttaa agaatcctta atatatttta   2400

ccaaattttt agtaactatt atgaaataca atggtgttcc aaaagaagaa agcactaaaa   2460

actcaactag caggaagcgg ttttgcttcc attgagccac gtcggtggtg tcatcctaca   2520

tgtagcataa tagagtctct cagcctttgc ttactggtgt ttccgacagt attaacccag   2580

tgcgtggcat gtctttgaag caaagcctgt cccgctagcc tgtgtgttca cacaccaaag   2640

gagaagggta ggcgaggggt tcggagtgta ttttcaggtt ggaatgtgaa ggttcctggc   2700

ttccatgtga cttgtaagtg tgccttgttt tttatttaaa ctatgtctgt agttgacaaa   2760

agtggcttca tcacaaattt ttttaaacgt ttctactttg gggttccatt taggagcttt   2820

ctagaaagtt gaggatgttt gaagcttccc ttctgtgttc cagtttgata tgggttaggt   2880

taaggaaaag gagatggtct cgatgtcatg gatttaaagt cagcatttgg attacaacac   2940

acattattgt gtgtcgagag gcagcattgg aaagagcctg attttctaaa atatgcatca   3000

agtgcataaa ttacaaatca gagctgagtg gggaggtgct tcagcagcag cgggatcaat   3060

acgatttcca ctgggaagag acaggaattc tacctacaca taggaaggcc aaggttgatc   3120

cacttaacct tgttattgta attttaaagc tggtatcggt agctgggaag ctttatgtgt   3180

gtgtatgtca gctcagcatc ttttaatcgt gtctgatttt actctcgtta cttctcgctg   3240

ttggaagcat ctctgggttt cttgtggcgt ctggtgtgga atggccttcc tctctaggtg   3300

cctgaggtgt ccgctgacgg gtggcctctc acccccctct agagaaacct gacatttaca   3360

atggattgta tttgtccggc aaaaaaggcg gattcattca tagagcagaa agaacctgtt   3420

ggcgtaaggt cttccactag ttagatggtt tcttttgggg aaatgtttat atttggtaac   3480

ttctagaaag ccagaaaatg gactctgatt tcatagcatt ttgataaaat gccacaaaat   3540

aagggctata gagagatttt tacaagtcag attttttgtt ccccaaatct tttaaatgaa   3600

gccagtgact cccagttctc aacacatggc cccagtcaag acagaacacc atggaaaaaa   3660

ccctgtaagt attatggcac tctccgaatc ctcctgaagg catttcctct acagacatag   3720

tgttacagga agtgaaatgc aaatgtgcaa ttttttttaa aggagctttt aaacaaagta   3780

ataataattg gtgttgagaa catcagttgc cttattctaa gatttcataa ggctgagttt   3840

gcacgcttgg acttcagttc tgctagcatg taaagagtgg tggactttaa aaccgtaaga   3900

ggtatcatta caagtcacct ggaacagact caaagaacag gttctttggg caacagacaa   3960

agaagaatca agttctgtgc tgtcccgtga gtgtgtctga gtaccattca ctggagttgc   4020

tgcttaggtc tgggacgtgt gtgtgactct taacaattgc tgtctgaaaa tgagagagaa   4080

gacttcggaa gcacattgtg ttcataatgt actccacaat ggccagtcca attgctatct   4140

atttttttat ccagaggctt aattaaatga tgtggtaaaa tgatgtttga gcattaagac   4200

aatgtaattc tttatttctg ggtggaaaga tataccggat taaatttatc tgtttaaaaa   4260

aatgacaaaa gttatcacca aaaccccctt tcccatcttg cactgtttgt tttggattgg   4320

gtttggggga aagagatgtt tttcttagtt gtctactttg tttgaacact tttgttgtgg   4380

ttcaagtgct gttttgtgtg ttgggaccaa acagttgtca ataaacttta caagcgagca   4440

tctat                                                               4445


<210>  8818
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8818

Met Lys Thr Ser Pro Arg Arg Ala Ser Ala Ser Trp Arg Cys Pro Asn 
1               5                   10                  15


Arg Thr Gln Pro Arg Asn Ser Ser Leu Glu Leu Thr Ala Val Gly Pro 
            20                  25                  30


Val Thr Gln Ser Arg Ser Phe Ser Ala 
        35                  40


<210>  8819
<211>  7736
<212>  DNA
<213>  Homo sapiens

<400>  8819
gcggtgcgga agcggaagtg aagggtgcgc ttggcggcgg cggcgggagc tgcggagtcg     60

ggaatcaaaa caaagggcct ggggggggcg gggggaaggc ggcggggccg gaatgtgagc    120

ggaggtggag ccggcggcag agggtggaag aatgaaagaa aagaaagatg aaaggatgtt    180

gaatcacttt gcatggctgt atgatggaag gaaacggaac tgagaactcc tgcagtagaa    240

cacgtggatg gcttcaacaa gataatgatg ctaagccatg gctttggaaa ttctctaatt    300

gcttttctcg tcctgagcag acgctgccac atagtcccca aacgaaagag tacatggaga    360

acaagaaagt tgctgtggaa ctaaaggatg taccatcacc ccttcatgct ggctctaagc    420

tttttccagc agtcccactt cctgatattc gttctcttca gcagcctaaa atacagcttt    480

cttctgtccc caaagtaagc tgctgtgctc attgccctaa tgaaccctcc acttcgccaa    540

tgcgttttgg tggtggtggt ggcggtagcg gaggtaccag tagcttgatt cacccgggcg    600

cactgttaga ctcgcaaagc accaggacaa tcacgtgtca ggtagggtca gggtttgctt    660

tccagtctgc atcttcactc cagaatgcct cagctaggaa caatttggca ggcattgcaa    720

gtgactttcc cagcatgtgt ctagagagta acctgtcttc ctgcaaacac ctgccctgtt    780

gtggaaaact ccacttccag tcatgtcatg gtaatgtgca caagctgcat cagtttccga    840

gtctgcaggg ctgcacctcc gctggctatt tcccctgttc tgatttcaca agcggggctc    900

cagggcattt ggaagagcac atttcacagt cggagctaac gcctcacttg tgcaccaact    960

ctttgcacct taatgtggta cctccggttt gtttaaaggg ctcactttac tgcgaagact   1020

gtctaaacaa gccagcaaga aatagcataa tcgatgcggc taaagtctgg ccaaatatac   1080

cacctccaaa tactcaacct gcacctcttg ctgtccctct gtgtaatggc tgtggaacca   1140

aaggaacagg gaaggagacc acgttgttat tggcgaccag tctaggcaaa gctgcttcaa   1200

aatttgggtc accagaagtt gcagtagctg gacaggtgct agaaaactta ccccccattg   1260

gagttttttg ggatattgaa aactgctccg ttccctctgg ccggtcagca actgctgttg   1320

tgcaaagaat ccgtgagaag ttttttaaag gccacagaga agcagaattc atctgtgtat   1380

gtgacatcag taaagaaaac aaggaagtta ttcaagagct gaataattgc caggtaaccg   1440

ttgcccacat caatgctact gcaaagaatg ccgctgatga taaactgcgg cagagtctcc   1500

gcagatttgc aaatacacac actgctccag ccacagtggt tcttgtgtca actgatgtca   1560

attttgcatt ggaacttagt gacctgagac acaggcatgg tttccacatt attttggtcc   1620

ataaaaacca ggcctcagaa gcactgctgc atcatgctaa cgagctgatc agatttgaag   1680

agttcatttc cgacttgccc cccaggttac cactaaaaat gccacagtgc cacactctgc   1740

tctatgttta taacctacca gcaaataagg atggcaagag cgtcagcaac aggctcagac   1800

gcctgtccga taattgtggt gggaaagtgc tgagtatcac aggctgcagt gcaattctcc   1860

gcttcataaa ccaagatagt gcagagcgcg ctcagaagcg aatggaaaac gaagatgtct   1920

ttggtaatag gatcattgtg tcatttactc caaaaaatag agaactctgt gaaacaaaga   1980

gttcaaatgc aattgctgat aaagtgaagt ctcccaaaaa acttaagaat ccaaaattgt   2040

gcctcatcaa agatgcaagt gaacaatctt ccagtgccaa agccacgcct ggaaaagggt   2100

cacaggcaaa ttctggatct gctacaaaaa atacaaatgt taaaagttta caggagctgt   2160

gccgcatgga gtcaaaaact ggtcatagaa acagtgagca ccagcaaggt cacctgaggc   2220

tggtcgtacc cactcacggt aactcaagtg ctgcagtgtc gacgccgaaa aactcggggg   2280

tggcagaacc cgtttacaaa accagtcaga aaaaggagaa cctcagtgcc cgaagtgtta   2340

ccagttctcc tgtagagaaa aaagataaag aggagactgt attccaagtg agttacccgt   2400

ctgcttttag caagttagtt gcatccaggc aagtcagtcc tctgctcgca tctcagtctt   2460

ggtcttctag gagtatgtct ccaaaccttt taaacagagc atccccgctt gctttcaaca   2520

ttgcaaattc gagcagcgaa gccgactgcc cagacccatt tgcaaatggt gctgatgtcc   2580

aagtcagcaa catagactac agattatccc ggaaggagct gcagcagctc ctgcaggaag   2640

catttgccag gcatggcaag gtgaagagtg ttgagctcag cccccataca gattatcaac   2700

tcaaggctgt tgtgcaaatg gaaaacttac aagatgcgat cggtgcagtg aatagcctcc   2760

acagatacaa aattggcagc aaaaagatcc tggtctcact tgccaccggg gctgccagca   2820

aatcactctc tttactgagt gcagaaacaa tgtctgttct tcaggatgcc cctgcctgtt   2880

gcctgcctct gtttaaattt acagatatct atgaaaaaaa gtttggacac aagttgaatg   2940

tgtcagatct atataaatta acagacacgg tcgcaatccg tgaacaagga aacggacggc   3000

tggtgtgtct cctacccagc agtcaggccc gccagagccc cttggggtct tcccagtcac   3060

acgacggctc ctccacgaat tgcagcccaa ttatatttga agagttagaa tatcacgagc   3120

ctgtctgcag acagcattgt tccaataagg atttcagcga acatgaattt gatccagact   3180

cttacaagat tccttttgtg attctttctt tgaagacatt tgcgccccag gttcacagtc   3240

ttctccagac ccacgagggc accgtgcctt tattgagctt tccagattgt tacattgcag   3300

agtttggcga tctagaagta gtgcaagaaa accaaggagg tgttccctta gaacacttca   3360

ttacctgtgt tccaggtgta aacattgcca ctgctcagaa tggcatcaaa gtggttaaat   3420

ggattcacaa caagcccccg cctcccaaca ctgacccttg gcttctgcgt tcgaagagtc   3480

ctgtaggtaa cccccagctg atccagttca gtagagaagt gattgacttg ctgaaaagcc   3540

agccatcttg tgtcataccc atcagtcatt tcatcccatc ctatcaccat cattttgcaa   3600

agcagtgccg agtgtcagac tacggatact ccaagctgat tgagttatta gaagcagtgc   3660

ctcatgtatt gcagattctt ggaatgggct ccaaacgtct gctgaccctt acccacaggg   3720

cccaggtgaa gcgctttact caggatttac taaaacttct caaatcccag gccagcaaac   3780

aggtcattgt gagagaattc tcacaggctt atcactggtg tttctcaaag gactgggatg   3840

tcactgaata tggtgtttgt gagttgattg acatcgtatc agagattcca gacacaacca   3900

tctgcttgtc ccaacaagat aatgaaatgg tgatttgtat ccccaaaaga gaacgcactc   3960

aggatgaaat agaaaggaca aaacagttct ccaaggatgt cgttgatttg ctgcgtcacc   4020

aaccccattt ccggatgccc tttaataaat ttatcccttc ttaccatcac cactttggcc   4080

ggcagtgcaa acttgcgtac tatgggttta ccaaactact tgaacttttt gaagccatac   4140

ctgatacttt acaagtattg gaatgtggag aagaaaagat ccttactctg acagaggtgg   4200

agcggttcaa agctctagct gcccagtttg ttaaactcct tcggtcccaa aaagataact   4260

gccttatgat gacagatctc cttacagaat atgctaaaac ttttggttat acatttcgtc   4320

tccaagacta tgatgtcagt tccatttcgg ctttaactca gaaactctgc catgtcgtga   4380

aggttgccga tatagaatct ggcagacaga ttcagctgat caaccgaaag tctctgcgat   4440

ctctcactgc ccagttgctg gtattgttga tgtcttggga aggaaccacc catctttctg   4500

ttgaggagct caagagacat tacgaaagta cccacaacac tccccttaac ccctgtgaat   4560

atggattcat gaccttgacc gaactgctga agagcctgcc atacttggtt gaggttttca   4620

ctaatgataa gatggaagaa tgtgtgaagc tcacaagtct gtatttgttt gcaaagaatg   4680

tgcggtcttt acttcatact taccactacc agcagatttt ccttcatgag ttttccatgg   4740

cctataccaa gtatgtcgga gaaactctgc agcccaagac ctacggccac agcagcgtgg   4800

aggagctctt gggagcaatt ccacaggtgg tctggataaa aggacatggt cataagagaa   4860

ttgtagtgtt aaaaaatgac atgaaaagtc gtttgagttc actcagtctc tcccctgcca   4920

atcatgaaaa ccagccctcg gagggcgagc gcatcctgga ggtgcccgaa tcgcacacag   4980

cctcggaact caagcttgga gctgacggca gtgggcccag tcacacagag caggagcttc   5040

tccgcctgac cgacgactcc cccgtcgacc tcctgtgtgc gcctgtcccc tcgtgcctgc   5100

cgtcccctca gctgagacca gaccccgtta tcctccaatc tgctgatctc attcagtttg   5160

aggagcgccc tcaagagcct tctgaaatta tgattttaaa ccaagaagaa aaaatggaga   5220

ttccaatacc aggaaagagc aaaactctga cctctgactc cagctcgtcc tgcatctcag   5280

cagctgtccc cgtgcctccc tgcccctcct cggaaacctc cgagtcactg ctcagcaagg   5340

accccgtgga aagcccggcc aaaaagcaac ccaaaaatag agtcaaattg gcagccaact   5400

tttccttagc acctataacc aagctttaac tcccatttgg aatatagaat taggatggga   5460

aaacactgtc tgattctgca cacaaaagtg ggtttcaaaa atacatcctt ttctgtgtca   5520

tgaaaacccc ccgaagccat tgacttcatc ttacctgtgt tctatcatgt ttttcttttc   5580

cattgaacac agctttgagc tgaagtcttt cttttcttct tcctttttct ttcttttttc   5640

aattatttga agaacttgtg gcatttgtta aagaatcctt aatatatttt accaaatttt   5700

tagtaactat tatgaaatac aatggtgttc caaaagaaga aagcactaaa aactcaacta   5760

gcaggaagcg gttttgcttc cattgagcca cgtcggtggt gtcatcctac atgtagcata   5820

atagagtctc tcagcctttg cttactggtg tttccgacag tattaaccca gtgcgtggca   5880

tgtctttgaa gcaaagcctg tcccgctagc ctgtgtgttc acacaccaaa ggagaagggt   5940

aggcgagggg ttcggagtgt attttcaggt tggaatgtga aggttcctgg cttccatgtg   6000

acttgtaagt gtgccttgtt ttttatttaa actatgtctg tagttgacaa aagtggcttc   6060

atcacaaatt tttttaaacg tttctacttt ggggttccat ttaggagctt tctagaaagt   6120

tgaggatgtt tgaagcttcc cttctgtgtt ccagtttgat atgggttagg ttaaggaaaa   6180

ggagatggtc tcgatgtcat ggatttaaag tcagcatttg gattacaaca cacattattg   6240

tgtgtcgaga ggcagcattg gaaagagcct gattttctaa aatatgcatc aagtgcataa   6300

attacaaatc agagctgagt ggggaggtgc ttcagcagca gcgggatcaa tacgatttcc   6360

actgggaaga gacaggaatt ctacctacac ataggaaggc caaggttgat ccacttaacc   6420

ttgttattgt aattttaaag ctggtatcgg tagctgggaa gctttatgtg tgtgtatgtc   6480

agctcagcat cttttaatcg tgtctgattt tactctcgtt acttctcgct gttggaagca   6540

tctctgggtt tcttgtggcg tctggtgtgg aatggccttc ctctctaggt gcctgaggtg   6600

tccgctgacg ggtggcctct cacccccctc tagagaaacc tgacatttac aatggattgt   6660

atttgtccgg caaaaaaggc ggattcattc atagagcaga aagaacctgt tggcgtaagg   6720

tcttccacta gttagatggt ttcttttggg gaaatgttta tatttggtaa cttctagaaa   6780

gccagaaaat ggactctgat ttcatagcat tttgataaaa tgccacaaaa taagggctat   6840

agagagattt ttacaagtca gattttttgt tccccaaatc ttttaaatga agccagtgac   6900

tcccagttct caacacatgg ccccagtcaa gacagaacac catggaaaaa accctgtaag   6960

tattatggca ctctccgaat cctcctgaag gcatttcctc tacagacata gtgttacagg   7020

aagtgaaatg caaatgtgca atttttttta aaggagcttt taaacaaagt aataataatt   7080

ggtgttgaga acatcagttg ccttattcta agatttcata aggctgagtt tgcacgcttg   7140

gacttcagtt ctgctagcat gtaaagagtg gtggacttta aaaccgtaag aggtatcatt   7200

acaagtcacc tggaacagac tcaaagaaca ggttctttgg gcaacagaca aagaagaatc   7260

aagttctgtg ctgtcccgtg agtgtgtctg agtaccattc actggagttg ctgcttaggt   7320

ctgggacgtg tgtgtgactc ttaacaattg ctgtctgaaa atgagagaga agacttcgga   7380

agcacattgt gttcataatg tactccacaa tggccagtcc aattgctatc tattttttta   7440

tccagaggct taattaaatg atgtggtaaa atgatgtttg agcattaaga caatgtaatt   7500

ctttatttct gggtggaaag atataccgga ttaaatttat ctgtttaaaa aaatgacaaa   7560

agttatcacc aaaaccccct ttcccatctt gcactgtttg ttttggattg ggtttggggg   7620

aaagagatgt ttttcttagt tgtctacttt gtttgaacac ttttgttgtg gttcaagtgc   7680

tgttttgtgt gttgggacca aacagttgtc aataaacttt acaagcgagc atctat       7736


<210>  8820
<211>  1742
<212>  PRT
<213>  Homo sapiens

<400>  8820

Met Met Glu Gly Asn Gly Thr Glu Asn Ser Cys Ser Arg Thr Arg Gly 
1               5                   10                  15


Trp Leu Gln Gln Asp Asn Asp Ala Lys Pro Trp Leu Trp Lys Phe Ser 
            20                  25                  30


Asn Cys Phe Ser Arg Pro Glu Gln Thr Leu Pro His Ser Pro Gln Thr 
        35                  40                  45


Lys Glu Tyr Met Glu Asn Lys Lys Val Ala Val Glu Leu Lys Asp Val 
    50                  55                  60


Pro Ser Pro Leu His Ala Gly Ser Lys Leu Phe Pro Ala Val Pro Leu 
65                  70                  75                  80


Pro Asp Ile Arg Ser Leu Gln Gln Pro Lys Ile Gln Leu Ser Ser Val 
                85                  90                  95


Pro Lys Val Ser Cys Cys Ala His Cys Pro Asn Glu Pro Ser Thr Ser 
            100                 105                 110


Pro Met Arg Phe Gly Gly Gly Gly Gly Gly Ser Gly Gly Thr Ser Ser 
        115                 120                 125


Leu Ile His Pro Gly Ala Leu Leu Asp Ser Gln Ser Thr Arg Thr Ile 
    130                 135                 140


Thr Cys Gln Val Gly Ser Gly Phe Ala Phe Gln Ser Ala Ser Ser Leu 
145                 150                 155                 160


Gln Asn Ala Ser Ala Arg Asn Asn Leu Ala Gly Ile Ala Ser Asp Phe 
                165                 170                 175


Pro Ser Met Cys Leu Glu Ser Asn Leu Ser Ser Cys Lys His Leu Pro 
            180                 185                 190


Cys Cys Gly Lys Leu His Phe Gln Ser Cys His Gly Asn Val His Lys 
        195                 200                 205


Leu His Gln Phe Pro Ser Leu Gln Gly Cys Thr Ser Ala Gly Tyr Phe 
    210                 215                 220


Pro Cys Ser Asp Phe Thr Ser Gly Ala Pro Gly His Leu Glu Glu His 
225                 230                 235                 240


Ile Ser Gln Ser Glu Leu Thr Pro His Leu Cys Thr Asn Ser Leu His 
                245                 250                 255


Leu Asn Val Val Pro Pro Val Cys Leu Lys Gly Ser Leu Tyr Cys Glu 
            260                 265                 270


Asp Cys Leu Asn Lys Pro Ala Arg Asn Ser Ile Ile Asp Ala Ala Lys 
        275                 280                 285


Val Trp Pro Asn Ile Pro Pro Pro Asn Thr Gln Pro Ala Pro Leu Ala 
    290                 295                 300


Val Pro Leu Cys Asn Gly Cys Gly Thr Lys Gly Thr Gly Lys Glu Thr 
305                 310                 315                 320


Thr Leu Leu Leu Ala Thr Ser Leu Gly Lys Ala Ala Ser Lys Phe Gly 
                325                 330                 335


Ser Pro Glu Val Ala Val Ala Gly Gln Val Leu Glu Asn Leu Pro Pro 
            340                 345                 350


Ile Gly Val Phe Trp Asp Ile Glu Asn Cys Ser Val Pro Ser Gly Arg 
        355                 360                 365


Ser Ala Thr Ala Val Val Gln Arg Ile Arg Glu Lys Phe Phe Lys Gly 
    370                 375                 380


His Arg Glu Ala Glu Phe Ile Cys Val Cys Asp Ile Ser Lys Glu Asn 
385                 390                 395                 400


Lys Glu Val Ile Gln Glu Leu Asn Asn Cys Gln Val Thr Val Ala His 
                405                 410                 415


Ile Asn Ala Thr Ala Lys Asn Ala Ala Asp Asp Lys Leu Arg Gln Ser 
            420                 425                 430


Leu Arg Arg Phe Ala Asn Thr His Thr Ala Pro Ala Thr Val Val Leu 
        435                 440                 445


Val Ser Thr Asp Val Asn Phe Ala Leu Glu Leu Ser Asp Leu Arg His 
    450                 455                 460


Arg His Gly Phe His Ile Ile Leu Val His Lys Asn Gln Ala Ser Glu 
465                 470                 475                 480


Ala Leu Leu His His Ala Asn Glu Leu Ile Arg Phe Glu Glu Phe Ile 
                485                 490                 495


Ser Asp Leu Pro Pro Arg Leu Pro Leu Lys Met Pro Gln Cys His Thr 
            500                 505                 510


Leu Leu Tyr Val Tyr Asn Leu Pro Ala Asn Lys Asp Gly Lys Ser Val 
        515                 520                 525


Ser Asn Arg Leu Arg Arg Leu Ser Asp Asn Cys Gly Gly Lys Val Leu 
    530                 535                 540


Ser Ile Thr Gly Cys Ser Ala Ile Leu Arg Phe Ile Asn Gln Asp Ser 
545                 550                 555                 560


Ala Glu Arg Ala Gln Lys Arg Met Glu Asn Glu Asp Val Phe Gly Asn 
                565                 570                 575


Arg Ile Ile Val Ser Phe Thr Pro Lys Asn Arg Glu Leu Cys Glu Thr 
            580                 585                 590


Lys Ser Ser Asn Ala Ile Ala Asp Lys Val Lys Ser Pro Lys Lys Leu 
        595                 600                 605


Lys Asn Pro Lys Leu Cys Leu Ile Lys Asp Ala Ser Glu Gln Ser Ser 
    610                 615                 620


Ser Ala Lys Ala Thr Pro Gly Lys Gly Ser Gln Ala Asn Ser Gly Ser 
625                 630                 635                 640


Ala Thr Lys Asn Thr Asn Val Lys Ser Leu Gln Glu Leu Cys Arg Met 
                645                 650                 655


Glu Ser Lys Thr Gly His Arg Asn Ser Glu His Gln Gln Gly His Leu 
            660                 665                 670


Arg Leu Val Val Pro Thr His Gly Asn Ser Ser Ala Ala Val Ser Thr 
        675                 680                 685


Pro Lys Asn Ser Gly Val Ala Glu Pro Val Tyr Lys Thr Ser Gln Lys 
    690                 695                 700


Lys Glu Asn Leu Ser Ala Arg Ser Val Thr Ser Ser Pro Val Glu Lys 
705                 710                 715                 720


Lys Asp Lys Glu Glu Thr Val Phe Gln Val Ser Tyr Pro Ser Ala Phe 
                725                 730                 735


Ser Lys Leu Val Ala Ser Arg Gln Val Ser Pro Leu Leu Ala Ser Gln 
            740                 745                 750


Ser Trp Ser Ser Arg Ser Met Ser Pro Asn Leu Leu Asn Arg Ala Ser 
        755                 760                 765


Pro Leu Ala Phe Asn Ile Ala Asn Ser Ser Ser Glu Ala Asp Cys Pro 
    770                 775                 780


Asp Pro Phe Ala Asn Gly Ala Asp Val Gln Val Ser Asn Ile Asp Tyr 
785                 790                 795                 800


Arg Leu Ser Arg Lys Glu Leu Gln Gln Leu Leu Gln Glu Ala Phe Ala 
                805                 810                 815


Arg His Gly Lys Val Lys Ser Val Glu Leu Ser Pro His Thr Asp Tyr 
            820                 825                 830


Gln Leu Lys Ala Val Val Gln Met Glu Asn Leu Gln Asp Ala Ile Gly 
        835                 840                 845


Ala Val Asn Ser Leu His Arg Tyr Lys Ile Gly Ser Lys Lys Ile Leu 
    850                 855                 860


Val Ser Leu Ala Thr Gly Ala Ala Ser Lys Ser Leu Ser Leu Leu Ser 
865                 870                 875                 880


Ala Glu Thr Met Ser Val Leu Gln Asp Ala Pro Ala Cys Cys Leu Pro 
                885                 890                 895


Leu Phe Lys Phe Thr Asp Ile Tyr Glu Lys Lys Phe Gly His Lys Leu 
            900                 905                 910


Asn Val Ser Asp Leu Tyr Lys Leu Thr Asp Thr Val Ala Ile Arg Glu 
        915                 920                 925


Gln Gly Asn Gly Arg Leu Val Cys Leu Leu Pro Ser Ser Gln Ala Arg 
    930                 935                 940


Gln Ser Pro Leu Gly Ser Ser Gln Ser His Asp Gly Ser Ser Thr Asn 
945                 950                 955                 960


Cys Ser Pro Ile Ile Phe Glu Glu Leu Glu Tyr His Glu Pro Val Cys 
                965                 970                 975


Arg Gln His Cys Ser Asn Lys Asp Phe Ser Glu His Glu Phe Asp Pro 
            980                 985                 990


Asp Ser Tyr Lys Ile Pro Phe Val Ile Leu Ser Leu Lys Thr Phe Ala 
        995                 1000                1005


Pro Gln Val His Ser Leu Leu Gln Thr His Glu Gly Thr Val Pro Leu 
    1010                1015                1020


Leu Ser Phe Pro Asp Cys Tyr Ile Ala Glu Phe Gly Asp Leu Glu Val 
1025                1030                1035                1040


Val Gln Glu Asn Gln Gly Gly Val Pro Leu Glu His Phe Ile Thr Cys 
                1045                1050                1055


Val Pro Gly Val Asn Ile Ala Thr Ala Gln Asn Gly Ile Lys Val Val 
            1060                1065                1070


Lys Trp Ile His Asn Lys Pro Pro Pro Pro Asn Thr Asp Pro Trp Leu 
        1075                1080                1085


Leu Arg Ser Lys Ser Pro Val Gly Asn Pro Gln Leu Ile Gln Phe Ser 
    1090                1095                1100


Arg Glu Val Ile Asp Leu Leu Lys Ser Gln Pro Ser Cys Val Ile Pro 
1105                1110                1115                1120


Ile Ser His Phe Ile Pro Ser Tyr His His His Phe Ala Lys Gln Cys 
                1125                1130                1135


Arg Val Ser Asp Tyr Gly Tyr Ser Lys Leu Ile Glu Leu Leu Glu Ala 
            1140                1145                1150


Val Pro His Val Leu Gln Ile Leu Gly Met Gly Ser Lys Arg Leu Leu 
        1155                1160                1165


Thr Leu Thr His Arg Ala Gln Val Lys Arg Phe Thr Gln Asp Leu Leu 
    1170                1175                1180


Lys Leu Leu Lys Ser Gln Ala Ser Lys Gln Val Ile Val Arg Glu Phe 
1185                1190                1195                1200


Ser Gln Ala Tyr His Trp Cys Phe Ser Lys Asp Trp Asp Val Thr Glu 
                1205                1210                1215


Tyr Gly Val Cys Glu Leu Ile Asp Ile Val Ser Glu Ile Pro Asp Thr 
            1220                1225                1230


Thr Ile Cys Leu Ser Gln Gln Asp Asn Glu Met Val Ile Cys Ile Pro 
        1235                1240                1245


Lys Arg Glu Arg Thr Gln Asp Glu Ile Glu Arg Thr Lys Gln Phe Ser 
    1250                1255                1260


Lys Asp Val Val Asp Leu Leu Arg His Gln Pro His Phe Arg Met Pro 
1265                1270                1275                1280


Phe Asn Lys Phe Ile Pro Ser Tyr His His His Phe Gly Arg Gln Cys 
                1285                1290                1295


Lys Leu Ala Tyr Tyr Gly Phe Thr Lys Leu Leu Glu Leu Phe Glu Ala 
            1300                1305                1310


Ile Pro Asp Thr Leu Gln Val Leu Glu Cys Gly Glu Glu Lys Ile Leu 
        1315                1320                1325


Thr Leu Thr Glu Val Glu Arg Phe Lys Ala Leu Ala Ala Gln Phe Val 
    1330                1335                1340


Lys Leu Leu Arg Ser Gln Lys Asp Asn Cys Leu Met Met Thr Asp Leu 
1345                1350                1355                1360


Leu Thr Glu Tyr Ala Lys Thr Phe Gly Tyr Thr Phe Arg Leu Gln Asp 
                1365                1370                1375


Tyr Asp Val Ser Ser Ile Ser Ala Leu Thr Gln Lys Leu Cys His Val 
            1380                1385                1390


Val Lys Val Ala Asp Ile Glu Ser Gly Arg Gln Ile Gln Leu Ile Asn 
        1395                1400                1405


Arg Lys Ser Leu Arg Ser Leu Thr Ala Gln Leu Leu Val Leu Leu Met 
    1410                1415                1420


Ser Trp Glu Gly Thr Thr His Leu Ser Val Glu Glu Leu Lys Arg His 
1425                1430                1435                1440


Tyr Glu Ser Thr His Asn Thr Pro Leu Asn Pro Cys Glu Tyr Gly Phe 
                1445                1450                1455


Met Thr Leu Thr Glu Leu Leu Lys Ser Leu Pro Tyr Leu Val Glu Val 
            1460                1465                1470


Phe Thr Asn Asp Lys Met Glu Glu Cys Val Lys Leu Thr Ser Leu Tyr 
        1475                1480                1485


Leu Phe Ala Lys Asn Val Arg Ser Leu Leu His Thr Tyr His Tyr Gln 
    1490                1495                1500


Gln Ile Phe Leu His Glu Phe Ser Met Ala Tyr Thr Lys Tyr Val Gly 
1505                1510                1515                1520


Glu Thr Leu Gln Pro Lys Thr Tyr Gly His Ser Ser Val Glu Glu Leu 
                1525                1530                1535


Leu Gly Ala Ile Pro Gln Val Val Trp Ile Lys Gly His Gly His Lys 
            1540                1545                1550


Arg Ile Val Val Leu Lys Asn Asp Met Lys Ser Arg Leu Ser Ser Leu 
        1555                1560                1565


Ser Leu Ser Pro Ala Asn His Glu Asn Gln Pro Ser Glu Gly Glu Arg 
    1570                1575                1580


Ile Leu Glu Val Pro Glu Ser His Thr Ala Ser Glu Leu Lys Leu Gly 
1585                1590                1595                1600


Ala Asp Gly Ser Gly Pro Ser His Thr Glu Gln Glu Leu Leu Arg Leu 
                1605                1610                1615


Thr Asp Asp Ser Pro Val Asp Leu Leu Cys Ala Pro Val Pro Ser Cys 
            1620                1625                1630


Leu Pro Ser Pro Gln Leu Arg Pro Asp Pro Val Ile Leu Gln Ser Ala 
        1635                1640                1645


Asp Leu Ile Gln Phe Glu Glu Arg Pro Gln Glu Pro Ser Glu Ile Met 
    1650                1655                1660


Ile Leu Asn Gln Glu Glu Lys Met Glu Ile Pro Ile Pro Gly Lys Ser 
1665                1670                1675                1680


Lys Thr Leu Thr Ser Asp Ser Ser Ser Ser Cys Ile Ser Ala Ala Val 
                1685                1690                1695


Pro Val Pro Pro Cys Pro Ser Ser Glu Thr Ser Glu Ser Leu Leu Ser 
            1700                1705                1710


Lys Asp Pro Val Glu Ser Pro Ala Lys Lys Gln Pro Lys Asn Arg Val 
        1715                1720                1725


Lys Leu Ala Ala Asn Phe Ser Leu Ala Pro Ile Thr Lys Leu 
    1730                1735                1740


<210>  8821
<211>  644
<212>  DNA
<213>  Homo sapiens

<400>  8821
tgtataacca aaagttttag catattctgt aaggagatct gtcatcataa ggcagttatc     60

tttttgggac cgaaggagtt taacaaactg ggcagctaga gctttgaacc gctccacctc    120

tgtcagagta aggatctttt cttctccaca ttccaatacc tttgaaaaca cacgggggga    180

ggaaagggaa aataaacaaa tcacgggtgt ttacagaata gcaaaaaaag tatgcagcta    240

gtaatgaaaa aacaagtcag cgttactgaa tgggtataaa gtttcagttg tgtaagatga    300

aaaagttcag aagatcggtt gcataacaat gtgaatgtgc tgaccactac tggacaggag    360

atataaagat agttacgaag gagcaccgtt taagaaccag ataatagaag gaggatacga    420

ccatacagtc accccttggt gttctcaagg gatcgggtcc aggaccctgc ctggatacca    480

aaatccgcac ctactcaagt cttgcggtct gccccgcgga aactgcagac acgaaaaatt    540

ggcccccagt atccatgagt ttcgcatccc tcaaatactg tactttctac ccgtaactgg    600

acctgtgcag ttctgacttc aactattaaa atttgaaagg caaa                     644


<210>  8822
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  8822

Pro Leu Leu Asp Arg Arg Tyr Lys Asp Ser Tyr Glu Gly Ala Pro Phe 
1               5                   10                  15


Lys Asn Gln Ile Ile Glu Gly Gly Tyr Asp His Thr Val Thr Pro Trp 
            20                  25                  30


Cys Ser Gln Gly Ile Gly Ser Arg Thr Leu Pro Gly Tyr Gln Asn Pro 
        35                  40                  45


His Leu Leu Lys Ser Cys Gly Leu Pro Arg Gly Asn Cys Arg His Glu 
    50                  55                  60


Lys Leu Ala Pro Ser Ile His Glu Phe Arg Ile Pro Gln Ile Leu Tyr 
65                  70                  75                  80


Phe Leu Pro Val Thr Gly Pro Val Gln Phe 
                85                  90


<210>  8823
<211>  565
<212>  DNA
<213>  Homo sapiens

<400>  8823
ctttcaacat tgcaaattcg agcagcgaag ccgactgccc agacccattt gcaaatggtg     60

ctgatgtcca agtcagcaac atagactaca gattatcccg gaaggagctg cagcagctcc    120

tgcaggaagc atttgccagg catggcaagg tgaagagtgt tgagctcagc ccccatacag    180

attatcaact caaggctgtt gtgcaaatgg aaaacttaca agatgcgatc ggtgcagtga    240

atagcctcca cagatacaaa attggcagca aaaagatcct ggtctcactt gccaccgggg    300

ctgccagcaa atcactctct ttactgaggt aagaaacaag caagctgttt atttcaggaa    360

ataacatttg acccagaaac aattttagaa ataataaaaa tagattcaat cacattccca    420

cccccttgtg atgattgcat gtggaataat gcttattcta gattgataca gttagaaaca    480

agccatttga ctcttgtcta agtcattaat caaagctgga atacagctta aacttgacag    540

gcacttggga gtaaaataat acgca                                          565


<210>  8824
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8824

Met Glu Asn Leu Gln Asp Ala Ile Gly Ala Val Asn Ser Leu His Arg 
1               5                   10                  15


Tyr Lys Ile Gly Ser Lys Lys Ile Leu Val Ser Leu Ala Thr Gly Ala 
            20                  25                  30


Ala Ser Lys Ser Leu Ser Leu Leu Arg 
        35                  40


<210>  8825
<211>  2364
<212>  DNA
<213>  Homo sapiens

<400>  8825
gggcggtgcg gtgcggaagc ggaagtgaag ggtgcgcttg gcggcggcgg cgggagctgc     60

ggagtcggga atcaaaacaa agggcctggg gggggcgggg ggaaggcggc ggggccggaa    120

tgtgagcgga ggtggagccg gcggcagagg gtggaagaat gaaagaaaag aaagatgaaa    180

ggatgttgaa tcactttgca tggctgtatg atggaaggaa acggaactga gaactcctgc    240

agtagaacac gtggatggct tcaacaagat aatgatgcta agccatggct ttggaaattc    300

tctaattgct tttctcgtcc tgagcagacg ctgccacata gtccccaaac gaaagagtac    360

atggagaaca agaaagttgc tgtggaacta aaggatgtac catcacccct tcatgctggc    420

tctaagcttt ttccagcagt cccacttcct gatattcgtt ctcttcagca gcctaaaata    480

cagctttctt ctgtccccaa agtaagctgc tgtgctcatt gccctaatga accctccact    540

tcgccaatgc gttttggtgg tggtggtggc ggtagcggag gtaccagtag cttgattcac    600

ccgggcgcac tgttagactc gcaaagcacc aggacaatca cgtgtcaggt agggtcaggg    660

tttgctttcc agtctgcatc ttcactccag aatgcctcag ctaggaacaa tttggcaggc    720

attgcaagtg actttcccag catgtgtcta gagagtaacc tgtcttcctg caaacacctg    780

ccctgttgtg gaaaactcca cttccagtca tgtcatggta atgtgcacaa gctgcatcag    840

tttccgagtc tgcagggctg cacctccgct ggctatttcc cctgttctga tttcacaagc    900

ggggctccag ggcatttgga agagcacatt tcacagtcgg agctaacgcc tcacttgtgc    960

accaactctt tgcaccttaa tgtggtacct ccggtttgtt taaagggctc actttactgc   1020

gaagactgtc taaacaagcc agcaagaaat agcataatcg atgcggctaa agtctggcca   1080

aatataccac ctccaaatac tcaacctgca cctcttgctg tccctctgtg taatggctgt   1140

ggaaccaaag gaacagggaa ggagaccacg ttgttattgg cgaccagtct aggcaaagct   1200

gcttcaaaat ttgggtcacc agaagttgca gtagctggac aggtgctaga aaacttaccc   1260

cccattggag ttttttggga tattgaaaac tgctccgttc cctctggccg gtcagcaact   1320

gctgttgtgc aaagaatccg tgagaagttt tttaaaggcc acagagaagc agaattcatc   1380

tgtgtatgtg acatcagtaa agaaaacaag gaagttattc aagagctgaa taattgccag   1440

gtaaccgttg cccacatcaa tgctactgca aagaatgccg ctgatgataa actgcggcag   1500

agtctccgca gatttgcaaa tacacacact gctccagcca cagtggttct tgtgtcaact   1560

gatgtcaatt ttgcattgga acttagtgac ctgagacaca ggcatggttt ccacattatt   1620

ttggtccata aaaaccaggc ctcagaagca ctgctgcatc atgctaacga gctgatcaga   1680

tttgaagagt tcatttccga cttgcccccc aggttaccac taaaaatgcc acagtgccac   1740

actctgctct atgtttataa cctaccagca aataaggatg gcaagagcgt cagcaacagg   1800

ctcagacgcc tgtccgataa ttgtggtggg aaagtgctga gtatcacagg ctgcagtgca   1860

attctccgct tcataaacca agatagtgca gagcgcgctc agaagcgaat ggaaaacgaa   1920

gatgtctttg gtaataggat cattgtgtca tttactccaa aaaatagaga actctgtgaa   1980

acaaagagtt caaatgcaat tgctgataaa gtgaagtctc ccaaaaaact taagaatcca   2040

aaattgtgcc tcatcaaaga tgcaagtgaa caatcttcca gtgccaaagc cacgcctgga   2100

aaagggtcac aggcaaattc tggatctgct acaaaaaata caaatgttaa aagtttacag   2160

gagctgtgcc gcatggagtc aaaaactggt catagaaaca gtgagcacca gcaaggtcac   2220

ctgaggctgg tcgtacccac tcacggtaac tcaagtgctg cagtgtcgac gccgaaaaac   2280

tcgggggtgg cagaacccgt ttacaaaacc agtcagaaaa aggagaacct cagtgcccga   2340

agtgttacca gttctcctgt agag                                          2364


<210>  8826
<211>  718
<212>  PRT
<213>  Homo sapiens

<400>  8826

Met Met Glu Gly Asn Gly Thr Glu Asn Ser Cys Ser Arg Thr Arg Gly 
1               5                   10                  15


Trp Leu Gln Gln Asp Asn Asp Ala Lys Pro Trp Leu Trp Lys Phe Ser 
            20                  25                  30


Asn Cys Phe Ser Arg Pro Glu Gln Thr Leu Pro His Ser Pro Gln Thr 
        35                  40                  45


Lys Glu Tyr Met Glu Asn Lys Lys Val Ala Val Glu Leu Lys Asp Val 
    50                  55                  60


Pro Ser Pro Leu His Ala Gly Ser Lys Leu Phe Pro Ala Val Pro Leu 
65                  70                  75                  80


Pro Asp Ile Arg Ser Leu Gln Gln Pro Lys Ile Gln Leu Ser Ser Val 
                85                  90                  95


Pro Lys Val Ser Cys Cys Ala His Cys Pro Asn Glu Pro Ser Thr Ser 
            100                 105                 110


Pro Met Arg Phe Gly Gly Gly Gly Gly Gly Ser Gly Gly Thr Ser Ser 
        115                 120                 125


Leu Ile His Pro Gly Ala Leu Leu Asp Ser Gln Ser Thr Arg Thr Ile 
    130                 135                 140


Thr Cys Gln Val Gly Ser Gly Phe Ala Phe Gln Ser Ala Ser Ser Leu 
145                 150                 155                 160


Gln Asn Ala Ser Ala Arg Asn Asn Leu Ala Gly Ile Ala Ser Asp Phe 
                165                 170                 175


Pro Ser Met Cys Leu Glu Ser Asn Leu Ser Ser Cys Lys His Leu Pro 
            180                 185                 190


Cys Cys Gly Lys Leu His Phe Gln Ser Cys His Gly Asn Val His Lys 
        195                 200                 205


Leu His Gln Phe Pro Ser Leu Gln Gly Cys Thr Ser Ala Gly Tyr Phe 
    210                 215                 220


Pro Cys Ser Asp Phe Thr Ser Gly Ala Pro Gly His Leu Glu Glu His 
225                 230                 235                 240


Ile Ser Gln Ser Glu Leu Thr Pro His Leu Cys Thr Asn Ser Leu His 
                245                 250                 255


Leu Asn Val Val Pro Pro Val Cys Leu Lys Gly Ser Leu Tyr Cys Glu 
            260                 265                 270


Asp Cys Leu Asn Lys Pro Ala Arg Asn Ser Ile Ile Asp Ala Ala Lys 
        275                 280                 285


Val Trp Pro Asn Ile Pro Pro Pro Asn Thr Gln Pro Ala Pro Leu Ala 
    290                 295                 300


Val Pro Leu Cys Asn Gly Cys Gly Thr Lys Gly Thr Gly Lys Glu Thr 
305                 310                 315                 320


Thr Leu Leu Leu Ala Thr Ser Leu Gly Lys Ala Ala Ser Lys Phe Gly 
                325                 330                 335


Ser Pro Glu Val Ala Val Ala Gly Gln Val Leu Glu Asn Leu Pro Pro 
            340                 345                 350


Ile Gly Val Phe Trp Asp Ile Glu Asn Cys Ser Val Pro Ser Gly Arg 
        355                 360                 365


Ser Ala Thr Ala Val Val Gln Arg Ile Arg Glu Lys Phe Phe Lys Gly 
    370                 375                 380


His Arg Glu Ala Glu Phe Ile Cys Val Cys Asp Ile Ser Lys Glu Asn 
385                 390                 395                 400


Lys Glu Val Ile Gln Glu Leu Asn Asn Cys Gln Val Thr Val Ala His 
                405                 410                 415


Ile Asn Ala Thr Ala Lys Asn Ala Ala Asp Asp Lys Leu Arg Gln Ser 
            420                 425                 430


Leu Arg Arg Phe Ala Asn Thr His Thr Ala Pro Ala Thr Val Val Leu 
        435                 440                 445


Val Ser Thr Asp Val Asn Phe Ala Leu Glu Leu Ser Asp Leu Arg His 
    450                 455                 460


Arg His Gly Phe His Ile Ile Leu Val His Lys Asn Gln Ala Ser Glu 
465                 470                 475                 480


Ala Leu Leu His His Ala Asn Glu Leu Ile Arg Phe Glu Glu Phe Ile 
                485                 490                 495


Ser Asp Leu Pro Pro Arg Leu Pro Leu Lys Met Pro Gln Cys His Thr 
            500                 505                 510


Leu Leu Tyr Val Tyr Asn Leu Pro Ala Asn Lys Asp Gly Lys Ser Val 
        515                 520                 525


Ser Asn Arg Leu Arg Arg Leu Ser Asp Asn Cys Gly Gly Lys Val Leu 
    530                 535                 540


Ser Ile Thr Gly Cys Ser Ala Ile Leu Arg Phe Ile Asn Gln Asp Ser 
545                 550                 555                 560


Ala Glu Arg Ala Gln Lys Arg Met Glu Asn Glu Asp Val Phe Gly Asn 
                565                 570                 575


Arg Ile Ile Val Ser Phe Thr Pro Lys Asn Arg Glu Leu Cys Glu Thr 
            580                 585                 590


Lys Ser Ser Asn Ala Ile Ala Asp Lys Val Lys Ser Pro Lys Lys Leu 
        595                 600                 605


Lys Asn Pro Lys Leu Cys Leu Ile Lys Asp Ala Ser Glu Gln Ser Ser 
    610                 615                 620


Ser Ala Lys Ala Thr Pro Gly Lys Gly Ser Gln Ala Asn Ser Gly Ser 
625                 630                 635                 640


Ala Thr Lys Asn Thr Asn Val Lys Ser Leu Gln Glu Leu Cys Arg Met 
                645                 650                 655


Glu Ser Lys Thr Gly His Arg Asn Ser Glu His Gln Gln Gly His Leu 
            660                 665                 670


Arg Leu Val Val Pro Thr His Gly Asn Ser Ser Ala Ala Val Ser Thr 
        675                 680                 685


Pro Lys Asn Ser Gly Val Ala Glu Pro Val Tyr Lys Thr Ser Gln Lys 
    690                 695                 700


Lys Glu Asn Leu Ser Ala Arg Ser Val Thr Ser Ser Pro Val 
705                 710                 715


<210>  8827
<211>  863
<212>  DNA
<213>  Homo sapiens

<400>  8827
tgggcttaaa gttacttgac ttttagattt gtcttctcct gaaaaacaga aataatctct     60

tagagtgata ctttttgaca gcttgattgc ttattaggtc aaccagtgag gttggtagcc    120

ttaaaacttg gcattcatta ataatttagt ttttctacca ctgagaatga taggtagttt    180

attatcttat tgtaacttgc catttatttt ccactacaag taattgaaaa tgttaacatt    240

tcttaagggt caccagaagt tgcagtagct ggacaggtgc tagaaaactt accccccatt    300

ggagtttttt gggatattga aaactgctcc gttccctctg gccggtcagc aactgctgtt    360

gtgcaaagaa tccgtgagaa gttttttaaa ggccacagag aagcagaatt catctgtgta    420

tgtgacatca gtaaagaaaa caaggaagtt attcaagagc tgaataattg ccaggtaacc    480

gttgcccaca tcaatgctac tgcaaagaat gccgctgatg ataaactgcg gcagagtctc    540

cgcagatttg caaatacaca cactgctcca gccacagtgg ttcttgtgtc aactgatgtc    600

aattttgcat tggaacttag tgacctgaga cacaggcatg gtttccacat tattttggtc    660

cataaaaacc aggcctcaga agcactgctg catcatgcta acgagctgat cagatttgaa    720

gagttcattt ccgacttgcc ccccaggtta ccactaaaaa tgccagtaag tgggtttgcg    780

ttatttttgc cattttccaa tattacattg tggaggctga aagacagccc ataataaggg    840

ggttgccagg cccagatggg gct                                            863


<210>  8828
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  8828

Met Leu Leu Gln Arg Met Pro Leu Met Ile Asn Cys Gly Arg Val Ser 
1               5                   10                  15


Ala Asp Leu Gln Ile His Thr Leu Leu Gln Pro Gln Trp Phe Leu Cys 
            20                  25                  30


Gln Leu Met Ser Ile Leu His Trp Asn Leu Val Thr 
        35                  40


<210>  8829
<211>  3936
<212>  DNA
<213>  Homo sapiens

<400>  8829
ggggggggcg gggcctcgcg gccctgcagc ctcgtcaggc tcagtcccct cccgataaac     60

ccctaaatag ggactttccc ggggggtgac cctggctttt ttggcgaaaa cccccagttt    120

aaggaggcct tccccctggc ttcacgttgt ggagtcgaaa ggaaccttga agcggagaat    180

gagctcgtga cgtggacccg aggaaaaaac ctgccaacca ggatttaata gaattcagct    240

ctttcaggct ttggagggaa ggcgatttga acgggatttc aatgaaaaac cctgtccctt    300

cggctttttt tttttcctct ctcgggtctc gtcacgtgat ggtcctactt tatttttaaa    360

aattaaatgg cgcatattcc ccagcatcct aaatctagtg caacctagtg gcaagtggag    420

aaaaaaataa ctgccaacct ggcttcctac gaggtccccc ggagttctcg caaagttgcg    480

acccagttgg caaaaataca gtgtgtgcaa agactcaact ggacattgcc accaagaatc    540

aagagatttt tggggacttt agcaagaaaa cgttattttt aaaagccctg ctccaaagct    600

ggttacaaat gaatactgcg tttccagtga caggttgggc gagcagaaag gaaatcttac    660

gacggagtct tgccctgtcg cctaggctag agtgcagtgg tgtgatctcg gctcactgca    720

accgccacct cccggtttcc cgtgattctc ctgcctcagc ctcctgagta gctgggatta    780

cagacaccat gccacaagga gagtgatctc ttcccctgtt ttcacaatgg aggactccgg    840

aaagactttc agctccgagg aggaagaagc taactattgg aaagatctgg cgatgaccta    900

caaacagagg gcagaaaata cgcaagagga actccgagaa ttccaggagg gaagccgaga    960

atatgaagct gaattggaga cgcagctgca acaaattgaa accaggaaca gagacctcct   1020

gtccgaaaat aaccgccttc gcatggagct ggaaaccatc aaggagaagt ttgaagtgca   1080

gcactctgaa ggctaccggc agatctcagc cttggaggat gacctcgcgc agaccaaagc   1140

cattaaagac caattgcaga aatacatcag agagctggag caagcaaatg acgacctgga   1200

aagagccaag cgcgccacga tcatgtctct cgaagacttt gagcagcgct tgaatcaggc   1260

catcgaaaga aatgccttcc tggaaagtga acttgatgaa aaagagaatc tcctggaatc   1320

tgttcagaga ctgaaggatg aagccagaga tttgcggcag gaactggccg tgcagcagaa   1380

gcaggagaaa cccaggaccc ccatgcccag ctcagtggaa gctgagagga cagacacagc   1440

tgtgcaggcc acgggctccg tgccgtccac gcccattgct caccgaggac ccagctcaag   1500

tttaaacaca cctgggagct tcagacgtgg cctggacgac tccaccgggg ggacccccct   1560

cacacctgcg gcccggatat cagccctcaa cattgtggga gacctactgc ggaaagtcgg   1620

ggcactggag tccaaactcg cttcctgccg gaacctcgtg tacgatcagt ccccaaaccg   1680

aacaggtggc ccagcctctg ggcggagcag caagaacaga gatggcgggg agagacggcc   1740

aagcagcacc agcgtgcctt tgggtgataa ggggttggac acgagttgcc gctggttgtc   1800

caaatcaaca accaggtcgt ccagctcctg ctgaagcctg ttcttggtct tttccagttt   1860

atcataagcg gccgccttct cctcgtactg ctgggtgagg ttctcgatct ccttctggaa   1920

cctcttcttc ccctcttcca gagcttccac ggtgctggca aagtcctgca gcttcttctt   1980

cgagtcggag agctacaagg acagcgtcca gggtagggtg agagggggac catgagtggc   2040

ccctgtccct ggccccacag actctgagaa gcgaagacca tgtctcctcg ttggagaaac   2100

ccaatagcag gggaagctgg ggggtcaagc accatcgcac caacactcca ccgcgatctg   2160

cctgcggggg atctcagcgc agagaagttg agaggaccca tgaaggaagc aaggacacgg   2220

ggcaggcacc tggatgttga gagtggagat gtggcgctcc aggttctgct tggcctccat   2280

ctcctcgtcc agctggtctt gcaggctgtt ccgctcctcc tccagctggc gcagcttcgt   2340

agacacgttg agcttctgcc gggtttcttc ttgaagcagc tcctgcaaaa gggatgcaaa   2400

gaggtcccag ggacctgccc cgaggaaggc caccccccag gtcccctgga tgatgtggca   2460

ggacactcac ctgggtgtcc tggagctggg aactgaggga cgccacgtcc ttggccagct   2520

taatggcctt cccctcggcc tcgttaagca tccctgtgac gctctcaact tcattctaag   2580

ggtgccaaga gactggttag tcaaagcctc tagaagggga tcctcgttga aaggagccct   2640

ttttactcaa aacacatggg ctagtacttg aggtgttcac tgattgagaa aatacccgtg   2700

aggtatggga ctctgataaa aaaaaaaaaa aacacacaca cacacaaaaa aaacagaatc   2760

tgtggcttga agggaactcc gtcacctatg agttgggacc ctggccctag actctgtggt   2820

tctaagaact tatttgagcc ccaatggtat tgactgggac ctgatcccac taaatggatc   2880

ctagatccct gccaaggttg gtagagacaa agcagcaggt ctgagagtcc agacgaggtg   2940

ctctggctgg tccactctct aaggctggag aagggagacc aggatggtac ttgaacgtcc   3000

cagggatgct gtcccatccc ttccttcctc actcctactc tttgaccctg atggccaaag   3060

ccagagacgc aggccctaaa ggtaaaaacg tcctctctgt attctctggc ttttactccc   3120

tagtgtctct gcataagtcc ctttgaggct gttagcctac ccctccatct cttccattga   3180

caaggaggat atgaatgatc ttgacactgc ttatatgagg gcggcaaaag ccctgctctc   3240

aactgcatgt gagaaaaaaa catctcactt aattcttccc tcgccccttg gtccctggct   3300

gtggacatgt taaacatttg tgaaaacttt ggccacgtcc ccatgagtgg caaggcaggg   3360

taaatggcta tgccaagtga aagaagacca aagacaaaaa gaccatgtca ttcagcagct   3420

taaaacccct caacagcttc acattgccca gagtaaggat caacatacat gtaataggtt   3480

ctcaaaagcc ctacatcatc tgggtacaag ctccccctcc aaccccactc tgtactatct   3540

ccccctaccc ccaaccccag ctgggcactc cagctctact ggctgtatgt ctctctccta   3600

atttttctac ttaccacagg gcctttgcac acgctgttcc ctctgcctgg tagacttatc   3660

catgctcctt agggaagcct ttcgtggctc ctcctccccc aggttaggcc ccctggttat   3720

ttacacttgg gcatcatgtg ccttcccttt gctgcatcat ttgacattca tttgtgtgat   3780

tattcatgtc tttcccttcc cttcccttcc ccttactcgg ctggagtcct actggggcag   3840

cgacagtgtc tcttcttcct tgctgttgga tctcaggatt aagcacagtg cctggcatac   3900

agcaggtgct caataaatac ttatcaaatt ggaaaa                             3936


<210>  8830
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  8830

Met Glu Asp Ser Gly Lys Thr Phe Ser Ser Glu Glu Glu Glu Ala Asn 
1               5                   10                  15


Tyr Trp Lys Asp Leu Ala Met Thr Tyr Lys Gln Arg Ala Glu Asn Thr 
            20                  25                  30


Gln Glu Glu Leu Arg Glu Phe Gln Glu Gly Ser Arg Glu Tyr Glu Ala 
        35                  40                  45


Glu Leu Glu Thr Gln Leu Gln Gln Ile Glu Thr Arg Asn Arg Asp Leu 
    50                  55                  60


Leu Ser Glu Asn Asn Arg Leu Arg Met Glu Leu Glu Thr Ile Lys Glu 
65                  70                  75                  80


Lys Phe Glu Val Gln His Ser Glu Gly Tyr Arg Gln Ile Ser Ala Leu 
                85                  90                  95


Glu Asp Asp Leu Ala Gln Thr Lys Ala Ile Lys Asp Gln Leu Gln Lys 
            100                 105                 110


Tyr Ile Arg Glu Leu Glu Gln Ala Asn Asp Asp Leu Glu Arg Ala Lys 
        115                 120                 125


Arg Ala Thr Ile Met Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn Gln 
    130                 135                 140


Ala Ile Glu Arg Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys Glu 
145                 150                 155                 160


Asn Leu Leu Glu Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp Leu 
                165                 170                 175


Arg Gln Glu Leu Ala Val Gln Gln Lys Gln Glu Lys Pro Arg Thr Pro 
            180                 185                 190


Met Pro Ser Ser Val Glu Ala Glu Arg Thr Asp Thr Ala Val Gln Ala 
        195                 200                 205


Thr Gly Ser Val Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser Ser 
    210                 215                 220


Ser Leu Asn Thr Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser Thr 
225                 230                 235                 240


Gly Gly Thr Pro Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn Ile 
                245                 250                 255


Val Gly Asp Leu Leu Arg Lys Val Gly Ala Leu Glu Ser Lys Leu Ala 
            260                 265                 270


Ser Cys Arg Asn Leu Val Tyr Asp Gln Ser Pro Asn Arg Thr Gly Gly 
        275                 280                 285


Pro Ala Ser Gly Arg Ser Ser Lys Asn Arg Asp Gly Gly Glu Arg Arg 
    290                 295                 300


Pro Ser Ser Thr Ser Val Pro Leu Gly Asp Lys Gly Leu Asp Thr Ser 
305                 310                 315                 320


Cys Arg Trp Leu Ser Lys Ser Thr Thr Arg Ser Ser Ser Ser Cys 
                325                 330                 335


<210>  8831
<211>  909
<212>  DNA
<213>  Homo sapiens

<400>  8831
cggggccgca ccgcccttcg cagccgcctc tgccgccgcc gccgcgttgg cctcgccgcc     60

cctgctcgga caccatgcca caaggagagt gatctcttcc cctgttttca caatggagga    120

ctccggaaag actttcagct ccgaggagga agaagctaac tattggaaag atctggcgat    180

gacctacaaa cagagggcag aaaatacgca agaggaactc cgagaattcc aggagggaag    240

ccgagaatat gaagctgaat tggagacgca gctgcaacaa attgaaacca ggaacagaga    300

cctcctgtcc gaaaataacc gccttcgcat ggagctggaa accatcaagg agaagtttga    360

agtgcagcac tctgaaggct accggcagat ctcagccttg gaggatgacc tcgcgcagac    420

caaagccatt aaagaccaat tgcagaaata catcagagag ctggagcaag caaatgacga    480

cctggaaaga gccaagcgcg ccacgatcat gtctctcgaa gactttgagc agcgcttgaa    540

tcaggccatc gaaagaaatg ccttcctgga aagtgaactt gatgaaaaag agaatctcct    600

ggaatctgtt cagagactga aggatgaagc cagagatttg cggcaggaac tggccgtgca    660

gcagaagcag gagaaaccca ggacccccat gcccagctca gtggaagctg agaggacaga    720

cacagctgtg caggccacgg gctccgtgcc gtccacgccc attgctcacc gaggacccag    780

ctcaagttta aacacacctg ggagcttcag acgtggcctg gacgactcca ccggggggac    840

ccccctcaca cctgcggccc ggatatcagc cctcaacatt gtgggagacc tactgcggaa    900

agtcggggt                                                            909


<210>  8832
<211>  264
<212>  PRT
<213>  Homo sapiens

<400>  8832

Met Glu Asp Ser Gly Lys Thr Phe Ser Ser Glu Glu Glu Glu Ala Asn 
1               5                   10                  15


Tyr Trp Lys Asp Leu Ala Met Thr Tyr Lys Gln Arg Ala Glu Asn Thr 
            20                  25                  30


Gln Glu Glu Leu Arg Glu Phe Gln Glu Gly Ser Arg Glu Tyr Glu Ala 
        35                  40                  45


Glu Leu Glu Thr Gln Leu Gln Gln Ile Glu Thr Arg Asn Arg Asp Leu 
    50                  55                  60


Leu Ser Glu Asn Asn Arg Leu Arg Met Glu Leu Glu Thr Ile Lys Glu 
65                  70                  75                  80


Lys Phe Glu Val Gln His Ser Glu Gly Tyr Arg Gln Ile Ser Ala Leu 
                85                  90                  95


Glu Asp Asp Leu Ala Gln Thr Lys Ala Ile Lys Asp Gln Leu Gln Lys 
            100                 105                 110


Tyr Ile Arg Glu Leu Glu Gln Ala Asn Asp Asp Leu Glu Arg Ala Lys 
        115                 120                 125


Arg Ala Thr Ile Met Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn Gln 
    130                 135                 140


Ala Ile Glu Arg Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys Glu 
145                 150                 155                 160


Asn Leu Leu Glu Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp Leu 
                165                 170                 175


Arg Gln Glu Leu Ala Val Gln Gln Lys Gln Glu Lys Pro Arg Thr Pro 
            180                 185                 190


Met Pro Ser Ser Val Glu Ala Glu Arg Thr Asp Thr Ala Val Gln Ala 
        195                 200                 205


Thr Gly Ser Val Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser Ser 
    210                 215                 220


Ser Leu Asn Thr Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser Thr 
225                 230                 235                 240


Gly Gly Thr Pro Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn Ile 
                245                 250                 255


Val Gly Asp Leu Leu Arg Lys Val 
            260


<210>  8833
<211>  3222
<212>  DNA
<213>  Homo sapiens

<400>  8833
cggggccgca ccgcccttcg cagccgcctc tgccgccgcc gccgcgttgg cctcgccgcc     60

cctgctcgga caccatgcca caaggagagt gatctcttcc cctgttttca caatggagga    120

ctccggaaag actttcagct ccgaggagga agaagctaac tattggaaag atctggcgat    180

gacctacaaa cagagggcag aaaatacgca agaggaactc cgagaattcc aggagggaag    240

ccgagaatat gaagctgaat tggagacgca gctgcaacaa attgaaacca ggaacagaga    300

cctcctgtcc gaaaataacc gccttcgcat ggagctggaa accatcaagg agaagtttga    360

agtgcagcac tctgaaggct accggcagat ctcagccttg gaggatgacc tcgcgcagac    420

caaagccatt aaagaccaat tgcagaaata catcagagag ctggagcaag caaatgacga    480

cctggaaaga gccaagcgcg ccacgatcat gtctctcgaa gactttgagc agcgcttgaa    540

tcaggccatc gaaagaaatg ccttcctgga aagtgaactt gatgaaaaag agaatctcct    600

ggaatctgtt cagagactga aggatgaagc cagagatttg cggcaggaac tggccgtgca    660

gcagaagcag gagaaaccca ggacccccat gcccagctca gtggaagctg agaggacaga    720

cacagctgtg caggccacgg gctccgtgcc gtccacgccc attgctcacc gaggacccag    780

ctcaagttta aacacacctg ggagcttcag acgtggcctg gacgactcca ccggggggac    840

ccccctcaca cctgcggccc ggatatcagc cctcaacatt gtgggagacc tactgcggaa    900

agtcggggca ctggagtcca aactcgcttc ctgccggaac ctcgtgtacg atcagtcccc    960

aaaccgaaca ggtggcccag cctctgggcg gagcagcaag aacagagatg gcggggagag   1020

acggccaagc agcaccagcg tgcctttggg tgataagggg ttggacacga gttgccgctg   1080

gttgtccaaa tcaacaacca ggtcgtccag ctcctgctga agcctgttct tggtcttttc   1140

cagtttatca taagcggccg ccttctcctc gtactgctgg gtgaggttct cgatctcctt   1200

ctggaacctc ttcttcccct cttccagagc ttccacggtg ctggcaaagt cctgcagctt   1260

cttcttcgag tcggagagct acaaggacag cgtccagggt agggtgagag ggggaccatg   1320

agtggcccct gtccctggcc ccacagactc tgagaagcga agaccatgtc tcctcgttgg   1380

agaaacccaa tagcagggga agctgggggg tcaagcacca tcgcaccaac actccaccgc   1440

gatctgcctg cgggggatct cagcgcagag aagttgagag gacccatgaa ggaagcaagg   1500

acacggggca ggcacctgga tgttgagagt ggagatgtgg cgctccaggt tctgcttggc   1560

ctccatctcc tcgtccagct ggtcttgcag gctgttccgc tcctcctcca gctggcgcag   1620

cttcgtagac acgttgagct tctgccgggt ttcttcttga agcagctcct gcaaaaggga   1680

tgcaaagagg tcccagggac ctgccccgag gaaggccacc ccccaggtcc cctggatgat   1740

gtggcaggac actcacctgg gtgtcctgga gctgggaact gagggacgcc acgtccttgg   1800

ccagcttaat ggccttcccc tcggcctcgt taagcatccc tgtgacgctc tcaacttcat   1860

tctaagggtg ccaagagact ggttagtcaa agcctctaga aggggatcct cgttgaaagg   1920

agcccttttt actcaaaaca catgggctag tacttgaggt gttcactgat tgagaaaata   1980

cccgtgaggt atgggactct gataaaaaaa aaaaaaaaca cacacacaca caaaaaaaac   2040

agaatctgtg gcttgaaggg aactccgtca cctatgagtt gggaccctgg ccctagactc   2100

tgtggttcta agaacttatt tgagccccaa tggtattgac tgggacctga tcccactaaa   2160

tggatcctag atccctgcca aggttggtag agacaaagca gcaggtctga gagtccagac   2220

gaggtgctct ggctggtcca ctctctaagg ctggagaagg gagaccagga tggtacttga   2280

acgtcccagg gatgctgtcc catcccttcc ttcctcactc ctactctttg accctgatgg   2340

ccaaagccag agacgcaggc cctaaaggta aaaacgtcct ctctgtattc tctggctttt   2400

actccctagt gtctctgcat aagtcccttt gaggctgtta gcctacccct ccatctcttc   2460

cattgacaag gaggatatga atgatcttga cactgcttat atgagggcgg caaaagccct   2520

gctctcaact gcatgtgaga aaaaaacatc tcacttaatt cttccctcgc cccttggtcc   2580

ctggctgtgg acatgttaaa catttgtgaa aactttggcc acgtccccat gagtggcaag   2640

gcagggtaaa tggctatgcc aagtgaaaga agaccaaaga caaaaagacc atgtcattca   2700

gcagcttaaa acccctcaac agcttcacat tgcccagagt aaggatcaac atacatgtaa   2760

taggttctca aaagccctac atcatctggg tacaagctcc ccctccaacc ccactctgta   2820

ctatctcccc ctacccccaa ccccagctgg gcactccagc tctactggct gtatgtctct   2880

ctcctaattt ttctacttac cacagggcct ttgcacacgc tgttccctct gcctggtaga   2940

cttatccatg ctccttaggg aagcctttcg tggctcctcc tcccccaggt taggccccct   3000

ggttatttac acttgggcat catgtgcctt ccctttgctg catcatttga cattcatttg   3060

tgtgattatt catgtctttc ccttcccttc ccttcccctt actcggctgg agtcctactg   3120

gggcagcgac agtgtctctt cttccttgct gttggatctc aggattaagc acagtgcctg   3180

gcatacagca ggtgctcaat aaatacttat caaattggaa aa                      3222


<210>  8834
<211>  335
<212>  PRT
<213>  Homo sapiens

<400>  8834

Met Glu Asp Ser Gly Lys Thr Phe Ser Ser Glu Glu Glu Glu Ala Asn 
1               5                   10                  15


Tyr Trp Lys Asp Leu Ala Met Thr Tyr Lys Gln Arg Ala Glu Asn Thr 
            20                  25                  30


Gln Glu Glu Leu Arg Glu Phe Gln Glu Gly Ser Arg Glu Tyr Glu Ala 
        35                  40                  45


Glu Leu Glu Thr Gln Leu Gln Gln Ile Glu Thr Arg Asn Arg Asp Leu 
    50                  55                  60


Leu Ser Glu Asn Asn Arg Leu Arg Met Glu Leu Glu Thr Ile Lys Glu 
65                  70                  75                  80


Lys Phe Glu Val Gln His Ser Glu Gly Tyr Arg Gln Ile Ser Ala Leu 
                85                  90                  95


Glu Asp Asp Leu Ala Gln Thr Lys Ala Ile Lys Asp Gln Leu Gln Lys 
            100                 105                 110


Tyr Ile Arg Glu Leu Glu Gln Ala Asn Asp Asp Leu Glu Arg Ala Lys 
        115                 120                 125


Arg Ala Thr Ile Met Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn Gln 
    130                 135                 140


Ala Ile Glu Arg Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys Glu 
145                 150                 155                 160


Asn Leu Leu Glu Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp Leu 
                165                 170                 175


Arg Gln Glu Leu Ala Val Gln Gln Lys Gln Glu Lys Pro Arg Thr Pro 
            180                 185                 190


Met Pro Ser Ser Val Glu Ala Glu Arg Thr Asp Thr Ala Val Gln Ala 
        195                 200                 205


Thr Gly Ser Val Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser Ser 
    210                 215                 220


Ser Leu Asn Thr Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser Thr 
225                 230                 235                 240


Gly Gly Thr Pro Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn Ile 
                245                 250                 255


Val Gly Asp Leu Leu Arg Lys Val Gly Ala Leu Glu Ser Lys Leu Ala 
            260                 265                 270


Ser Cys Arg Asn Leu Val Tyr Asp Gln Ser Pro Asn Arg Thr Gly Gly 
        275                 280                 285


Pro Ala Ser Gly Arg Ser Ser Lys Asn Arg Asp Gly Gly Glu Arg Arg 
    290                 295                 300


Pro Ser Ser Thr Ser Val Pro Leu Gly Asp Lys Gly Leu Asp Thr Ser 
305                 310                 315                 320


Cys Arg Trp Leu Ser Lys Ser Thr Thr Arg Ser Ser Ser Ser Cys 
                325                 330                 335


<210>  8835
<211>  2632
<212>  DNA
<213>  Homo sapiens

<400>  8835
ctcctagaca ccatgccaca aggagagtga tctcttcccc tgttttcaca atggaggact     60

ccggaaagac tttcagctcc gaggaggaag aagctaacta ttggaaagat ctggcgatga    120

cctacaaaca gaggtcagtc cgagccacgg gctccgtgcc gtccacgccc attgctcacc    180

gaggacccag ctcaagttta aacacacctg ggagcttcag acgtggcctg gacgactcca    240

ccggggggac ccccctcaca cctgcggccc ggatatcagc cctcaacatt gtgggagacc    300

tactgcggaa agtcggggca ctggagtcca aactcgcttc ctgccggaac ctcgtgtacg    360

atcagtcccc aaaccgaaca ggtggcccag cctctgggcg gagcagcaag aacagagatg    420

gcggggagag acggccaagc agcaccagcg tgcctttggg tgataagggg ttggacacga    480

gttgccgctg gttgtccaaa tcaacaacca ggtcgtccag ctcctgctga agcctgttct    540

tggtcttttc cagtttatca taagcggccg ccttctcctc gtactgctgg gtgaggttct    600

cgatctcctt ctggaacctc ttcttcccct cttccagagc ttccacggtg ctggcaaagt    660

cctgcagctt cttcttcgag tcggagagct acaaggacag cgtccagggt agggtgagag    720

ggggaccatg agtggcccct gtccctggcc ccacagactc tgagaagcga agaccatgtc    780

tcctcgttgg agaaacccaa tagcagggga agctgggggg tcaagcacca tcgcaccaac    840

actccaccgc gatctgcctg cgggggatct cagcgcagag aagttgagag gacccatgaa    900

ggaagcaagg acacggggca ggcacctgga tgttgagagt ggagatgtgg cgctccaggt    960

tctgcttggc ctccatctcc tcgtccagct ggtcttgcag gctgttccgc tcctcctcca   1020

gctggcgcag cttcgtagac acgttgagct tctgccgggt ttcttcttga agcagctcct   1080

gcaaaaggga tgcaaagagg tcccagggac ctgccccgag gaaggccacc ccccaggtcc   1140

cctggatgat gtggcaggac actcacctgg gtgtcctgga gctgggaact gagggacgcc   1200

acgtccttgg ccagcttaat ggccttcccc tcggcctcgt taagcatccc tgtgacgctc   1260

tcaacttcat tctaagggtg ccaagagact ggttagtcaa agcctctaga aggggatcct   1320

cgttgaaagg agcccttttt actcaaaaca catgggctag tacttgaggt gttcactgat   1380

tgagaaaata cccgtgaggt atgggactct gataaaaaaa aaaaaaaaca cacacacaca   1440

caaaaaaaac agaatctgtg gcttgaaggg aactccgtca cctatgagtt gggaccctgg   1500

ccctagactc tgtggttcta agaacttatt tgagccccaa tggtattgac tgggacctga   1560

tcccactaaa tggatcctag atccctgcca aggttggtag agacaaagca gcaggtctga   1620

gagtccagac gaggtgctct ggctggtcca ctctctaagg ctggagaagg gagaccagga   1680

tggtacttga acgtcccagg gatgctgtcc catcccttcc ttcctcactc ctactctttg   1740

accctgatgg ccaaagccag agacgcaggc cctaaaggta aaaacgtcct ctctgtattc   1800

tctggctttt actccctagt gtctctgcat aagtcccttt gaggctgtta gcctacccct   1860

ccatctcttc cattgacaag gaggatatga atgatcttga cactgcttat atgagggcgg   1920

caaaagccct gctctcaact gcatgtgaga aaaaaacatc tcacttaatt cttccctcgc   1980

cccttggtcc ctggctgtgg acatgttaaa catttgtgaa aactttggcc acgtccccat   2040

gagtggcaag gcagggtaaa tggctatgcc aagtgaaaga agaccaaaga caaaaagacc   2100

atgtcattca gcagcttaaa acccctcaac agcttcacat tgcccagagt aaggatcaac   2160

atacatgtaa taggttctca aaagccctac atcatctggg tacaagctcc ccctccaacc   2220

ccactctgta ctatctcccc ctacccccaa ccccagctgg gcactccagc tctactggct   2280

gtatgtctct ctcctaattt ttctacttac cacagggcct ttgcacacgc tgttccctct   2340

gcctggtaga cttatccatg ctccttaggg aagcctttcg tggctcctcc tcccccaggt   2400

taggccccct ggttatttac acttgggcat catgtgcctt ccctttgctg catcatttga   2460

cattcatttg tgtgattatt catgtctttc ccttcccttc ccttcccctt actcggctgg   2520

agtcctactg gggcagcgac agtgtctctt cttccttgct gttggatctc aggattaagc   2580

acagtgcctg gcatacagca ggtgctcaat aaatacttat caaattggaa aa           2632


<210>  8836
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  8836

Met Glu Asp Ser Gly Lys Thr Phe Ser Ser Glu Glu Glu Glu Ala Asn 
1               5                   10                  15


Tyr Trp Lys Asp Leu Ala Met Thr Tyr Lys Gln Arg Ser Val Arg Ala 
            20                  25                  30


Thr Gly Ser Val Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser Ser 
        35                  40                  45


Ser Leu Asn Thr Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser Thr 
    50                  55                  60


Gly Gly Thr Pro Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn Ile 
65                  70                  75                  80


Val Gly Asp Leu Leu Arg Lys Val Gly Ala Leu Glu Ser Lys Leu Ala 
                85                  90                  95


Ser Cys Arg Asn Leu Val Tyr Asp Gln Ser Pro Asn Arg Thr Gly Gly 
            100                 105                 110


Pro Ala Ser Gly Arg Ser Ser Lys Asn Arg Asp Gly Gly Glu Arg Arg 
        115                 120                 125


Pro Ser Ser Thr Ser Val Pro Leu Gly Asp Lys Gly Leu Asp Thr Ser 
    130                 135                 140


Cys Arg Trp Leu Ser Lys Ser Thr Thr Arg Ser Ser Ser Ser Cys 
145                 150                 155


<210>  8837
<211>  322
<212>  DNA
<213>  Homo sapiens

<400>  8837
tccgaggagg aagaagctaa ctattggaaa gatctggcga tgacctacaa acagagggca     60

gaaaatacgc aagaggaact ccgagaattc caggagggaa gccgagaata tgaagacctg    120

gctgaatttt ttgtattttt aatagagacg gggttttgcc atgttgccca gtgtggtctt    180

gaactcctgg cctcaagtga tcctcccatc tcggcctccc agaatgctgg gatttcaagc    240

atgagccatc gttcccatgc cccattgtgt tgcactaacc caagcggagg tcctgattgg    300

tctttttttt ttttttcttt tt                                             322


<210>  8838
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  8838

Met Thr Tyr Lys Gln Arg Ala Glu Asn Thr Gln Glu Glu Leu Arg Glu 
1               5                   10                  15


Phe Gln Glu Gly Ser Arg Glu Tyr Glu Asp Leu Ala Glu Phe Phe Val 
            20                  25                  30


Phe Leu Ile Glu Thr Gly Phe Cys His Val Ala Gln Cys Gly Leu Glu 
        35                  40                  45


Leu Leu Ala Ser Ser Asp Pro Pro Ile Ser Ala Ser Gln Asn Ala Gly 
    50                  55                  60


Ile Ser Ser Met Ser His Arg Ser His Ala Pro Leu Cys Cys Thr Asn 
65                  70                  75                  80


Pro Ser Gly Gly Pro Asp Trp Ser Phe Phe Phe Phe Ser 
                85                  90


<210>  8839
<211>  503
<212>  DNA
<213>  Homo sapiens

<400>  8839
cagctttcat agtcacaaat tattgcaata ttttgctgtt atactaaata tgggtttttt     60

ttgtttgttt ttaagacaga gtctagctct gttacccagg ttgcagtgag ctgagattgt    120

gctgttgcgc tccagcctgg gcaacagagt gagacttcat ctcaaaaaag aaaaaaaaag    180

gtgaaaggat gacttaaacc cagggtgtcg aggttgcagg gaaattcaga aatgccactg    240

aagggccagg catggtgtcc aacacctaca atcccagcac tttgggaggc agaagcaggt    300

gcatcacctg aagtcgggag ttcgagacca gcgtggccaa catggtggaa tgctgtctct    360

actaaaaata caaaaattag caggatgtgg tggtgcgtgc ctgtaatccc agctacttgg    420

gaggctgaga cagaagaatc atttgaaccc cggaggcaga ggttgcactc cgcctgggtg    480

acaagagtgg aactccatct taa                                            503


<210>  8840
<211>  89
<212>  PRT
<213>  Homo sapiens

<400>  8840

Met Pro Leu Lys Gly Gln Ala Trp Cys Pro Thr Pro Thr Ile Pro Ala 
1               5                   10                  15


Leu Trp Glu Ala Glu Ala Gly Ala Ser Pro Glu Val Gly Ser Ser Arg 
            20                  25                  30


Pro Ala Trp Pro Thr Trp Trp Asn Ala Val Ser Thr Lys Asn Thr Lys 
        35                  40                  45


Ile Ser Arg Met Trp Trp Cys Val Pro Val Ile Pro Ala Thr Trp Glu 
    50                  55                  60


Ala Glu Thr Glu Glu Ser Phe Glu Pro Arg Arg Gln Arg Leu His Ser 
65                  70                  75                  80


Ala Trp Val Thr Arg Val Glu Leu His 
                85


<210>  8841
<211>  2306
<212>  DNA
<213>  Homo sapiens

<400>  8841
tataacagat tgttttctta cagcacttgg cagtgccttt accacagtgt ttatgccctt     60

cacaagaagg ggttgtgagc agggcagctg ggctggtact gggcattttg aacttccact    120

gagaggttaa atatgatctc ttccacctgc ttaagtgcat cttatgcctg gcacaatgcc    180

tcatgcctgt aatctcagta actcaggagg ctgaggcggg aggatctctt gagcccaaga    240

gtttgagatt gcatggtata atctgggctc actacaacct ctgcttcctg gcagttctcc    300

cacctcagcc tcccaagtag ctgggattac actacaactg gctaattttt gtatttctag    360

tagagacagg attttgccat ttgcccaagc ttgccaggct ggtcttgaac tcctgatctc    420

aggtcttcca cctgcctcgg cctcccaaag ggctgggatt acaggcatga gccaccttgc    480

ccagtcatat taggttattt ttaatgctgg ttggcattgt gagcttgcaa gagaagatgg    540

agcatagtgg tcttctcaaa ccaccaaatg ccacatgcag tcctgatagg gctttggctt    600

attgctgagt gctgtgtggg cagcatctta tttaatcctc atgacagcct cgtgcacccc    660

atgagctatg atgagtccca ttctgcaggt aaagagccca tgccccagaa ggttaaggga    720

cttggcccac tctgtggcat ctaggaagtt tggggctggg acttgtgccc aggtgtgtct    780

gacccttcgc acctcctgga tccgcggtgc tggagggatg ctgcggtttg tcctcttgga    840

taactctgct tttctcttcg ccagcgccac gatcatgtct ctcgaagact ttgagcagcg    900

cttgaatcag gccatcgaaa gaaatgcctt cctggaaagt gaacttgatg aaaaagagaa    960

tctcctggaa tctgttcaga gactgaagga tgaagccaga gatttgcggc aggaactggc   1020

cgtgcagcag aagcaggaga aacccaggac ccccatgccc agctcagtgg aagctgagag   1080

gacagacaca gctgtgcagg ccacgggctc cgtgccgtcc acgcccattg ctcaccgagg   1140

acccagctca agtttaaaca cacctgggag cttcagacgt ggcctggacg actccaccgg   1200

ggggaccccc ctcacacctg cggcccggat atcagccctc aacattgtgg gagacctact   1260

gcggaaagtc ggggtaagac cacactttcc tggcgtttgg tgccttcctg cctgtctttc   1320

aggatgtgtg aagggggttg atctagttcc ttccctctct tctttttttc ttttttttta   1380

gagacagggt cttgctctgt tgctcaggct ggagtgtagt ggtatgatca caactcactg   1440

cagcctcaaa atcctgggtt caagcgatcc tctcacctta gcttcccgag gagcttggac   1500

cacaggtgtg cgccactatg cctggctgat actttcattt ttttgtagta atgtgggtat   1560

cgctgtgttg cccaggctgg tcttaaactc ctggcctcaa gtgatcctcc caggttggcc   1620

tcccaaagtt ctgggattac aggcatgagc caatgcgtcc agcccctttc atagcagtgt   1680

ggtgagtttt aggtgtggct gctcctttag catccctggg aatcattaga gcttcctgtg   1740

ggagttactg ccagacactc agagctctga ctcgaagccc tgctctgaac cctatgtatg   1800

tctctttcct tttaccgttt ttcctctagg aaatttggga aattagggtg atatgtgtgt   1860

tttttcctta actcgaaaaa ttaaggagca cttggaaact gccttctctt ttggccgggt   1920

gctcatacct gtaatcccag tgctttggga ggccaagatg ggtggatcac ctgaagtcag   1980

gaattcaaga ccagcctggc caacatggtg aaaccccatc tctactaaaa atacaaaaat   2040

tagccaggaa tggtggtggg cacctgcgat cccagctact tgagaggctt atgcaggaaa   2100

attgtttgaa tccgggaggc ggaggttgca gtgagctgag atcgcaccgc tgggtgacaa   2160

agtgagactt ggtctcaaaa aaaaaaaaaa aaaaaatctt gaaagcctag ggcaaagaat   2220

ttggcctttc agcttttatg ttaattacag ggagggatcc ttttgtgctt aagtaaaaac   2280

ataggtattc tttgtagttt attttt                                        2306


<210>  8842
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  8842

Met Met Ser Pro Ile Leu Gln Val Lys Ser Pro Cys Pro Arg Arg Leu 
1               5                   10                  15


Arg Asp Leu Ala His Ser Val Ala Ser Arg Lys Phe Gly Ala Gly Thr 
            20                  25                  30


Cys Ala Gln Val Cys Leu Thr Leu Arg Thr Ser Trp Ile Arg Gly Ala 
        35                  40                  45


Gly Gly Met Leu Arg Phe Val Leu Leu Asp Asn Ser Ala Phe Leu Phe 
    50                  55                  60


Ala Ser Ala Thr Ile Met Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn 
65                  70                  75                  80


Gln Ala Ile Glu Arg Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys 
                85                  90                  95


Glu Asn Leu Leu Glu Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp 
            100                 105                 110


Leu Arg Gln Glu Leu Ala Val Gln Gln Lys Gln Glu Lys Pro Arg Thr 
        115                 120                 125


Pro Met Pro Ser Ser Val Glu Ala Glu Arg Thr Asp Thr Ala Val Gln 
    130                 135                 140


Ala Thr Gly Ser Val Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser 
145                 150                 155                 160


Ser Ser Leu Asn Thr Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser 
                165                 170                 175


Thr Gly Gly Thr Pro Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn 
            180                 185                 190


Ile Val Gly Asp Leu Leu Arg Lys Val Gly Val Arg Pro His Phe Pro 
        195                 200                 205


Gly Val Trp Cys Leu Pro Ala Cys Leu Ser Gly Cys Val Lys Gly Val 
    210                 215                 220


Asp Leu Val Pro Ser Leu Ser Ser Phe Phe Leu Phe Phe 
225                 230                 235


<210>  8843
<211>  2573
<212>  DNA
<213>  Homo sapiens

<400>  8843
gcgccacgat catgtctctc gaagactttg agcagcgctt gaatcaggcc atcgaaagaa     60

atgccttcct ggaaagtgaa cttgatgaaa aagagaatct cctggaatct gttcagagac    120

tgaaggatga agccagagat ttgcggcagg aactggccgt gcagcagaag caggagaaac    180

ccaggacccc catgcccagc tcagtggaag ctgagaggac agacacagct gtgcaggcca    240

cgggctccgt gccgtccacg cccattgctc accgaggacc cagctcaagt ttaaacacac    300

ctgggagctt cagacgtggc ctggacgact ccaccggggg gacccccctc acacctgcgg    360

cccggatatc agccctcaac attgtgggag acctactgcg gaaagtcggg gttggacacg    420

agttgccgct ggttgtccaa atcaacaacc aggtcgtcca gctcctgctg aagcctgttc    480

ttggtctttt ccagtttatc ataagcggcc gccttctcct cgtactgctg ggtgaggttc    540

tcgatctcct tctggaacct cttcttcccc tcttccagag cttccacggt gctggcaaag    600

tcctgcagct tcttcttcga gtcggagagc tacaaggaca gcgtccaggg tagggtgaga    660

gggggaccat gagtggcccc tgtccctggc cccacagact ctgagaagcg aagaccatgt    720

ctcctcgttg gagaaaccca atagcagggg aagctggggg gtcaagcacc atcgcaccaa    780

cactccaccg cgatctgcct gcgggggatc tcagcgcaga gaagttgaga ggacccatga    840

aggaagcaag gacacggggc aggcacctgg atgttgagag tggagatgtg gcgctccagg    900

ttctgcttgg cctccatctc ctcgtccagc tggtcttgca ggctgttccg ctcctcctcc    960

agctggcgca gcttcgtaga cacgttgagc ttctgccggg tttcttcttg aagcagctcc   1020

tgcaaaaggg atgcaaagag gtcccaggga cctgccccga ggaaggccac cccccaggtc   1080

ccctggatga tgtggcagga cactcacctg ggtgtcctgg agctgggaac tgagggacgc   1140

cacgtccttg gccagcttaa tggccttccc ctcggcctcg ttaagcatcc ctgtgacgct   1200

ctcaacttca ttctaagggt gccaagagac tggttagtca aagcctctag aaggggatcc   1260

tcgttgaaag gagccctttt tactcaaaac acatgggcta gtacttgagg tgttcactga   1320

ttgagaaaat acccgtgagg tatgggactc tgataaaaaa aaaaaaaaac acacacacac   1380

acaaaaaaaa cagaatctgt ggcttgaagg gaactccgtc acctatgagt tgggaccctg   1440

gccctagact ctgtggttct aagaacttat ttgagcccca atggtattga ctgggacctg   1500

atcccactaa atggatccta gatccctgcc aaggttggta gagacaaagc agcaggtctg   1560

agagtccaga cgaggtgctc tggctggtcc actctctaag gctggagaag ggagaccagg   1620

atggtacttg aacgtcccag ggatgctgtc ccatcccttc cttcctcact cctactcttt   1680

gaccctgatg gccaaagcca gagacgcagg ccctaaaggt aaaaacgtcc tctctgtatt   1740

ctctggcttt tactccctag tgtctctgca taagtccctt tgaggctgtt agcctacccc   1800

tccatctctt ccattgacaa ggaggatatg aatgatcttg acactgctta tatgagggcg   1860

gcaaaagccc tgctctcaac tgcatgtgag aaaaaaacat ctcacttaat tcttccctcg   1920

ccccttggtc cctggctgtg gacatgttaa acatttgtga aaactttggc cacgtcccca   1980

tgagtggcaa ggcagggtaa atggctatgc caagtgaaag aagaccaaag acaaaaagac   2040

catgtcattc agcagcttaa aacccctcaa cagcttcaca ttgcccagag taaggatcaa   2100

catacatgta ataggttctc aaaagcccta catcatctgg gtacaagctc cccctccaac   2160

cccactctgt actatctccc cctaccccca accccagctg ggcactccag ctctactggc   2220

tgtatgtctc tctcctaatt tttctactta ccacagggcc tttgcacacg ctgttccctc   2280

tgcctggtag acttatccat gctccttagg gaagcctttc gtggctcctc ctcccccagg   2340

ttaggccccc tggttattta cacttgggca tcatgtgcct tccctttgct gcatcatttg   2400

acattcattt gtgtgattat tcatgtcttt cccttccctt cccttcccct tactcggctg   2460

gagtcctact ggggcagcga cagtgtctct tcttccttgc tgttggatct caggattaag   2520

cacagtgcct ggcatacagc aggtgctcaa taaatactta tcaaattgga aaa          2573


<210>  8844
<211>  213
<212>  PRT
<213>  Homo sapiens

<400>  8844

Met Ser Leu Glu Asp Phe Glu Gln Arg Leu Asn Gln Ala Ile Glu Arg 
1               5                   10                  15


Asn Ala Phe Leu Glu Ser Glu Leu Asp Glu Lys Glu Asn Leu Leu Glu 
            20                  25                  30


Ser Val Gln Arg Leu Lys Asp Glu Ala Arg Asp Leu Arg Gln Glu Leu 
        35                  40                  45


Ala Val Gln Gln Lys Gln Glu Lys Pro Arg Thr Pro Met Pro Ser Ser 
    50                  55                  60


Val Glu Ala Glu Arg Thr Asp Thr Ala Val Gln Ala Thr Gly Ser Val 
65                  70                  75                  80


Pro Ser Thr Pro Ile Ala His Arg Gly Pro Ser Ser Ser Leu Asn Thr 
                85                  90                  95


Pro Gly Ser Phe Arg Arg Gly Leu Asp Asp Ser Thr Gly Gly Thr Pro 
            100                 105                 110


Leu Thr Pro Ala Ala Arg Ile Ser Ala Leu Asn Ile Val Gly Asp Leu 
        115                 120                 125


Leu Arg Lys Val Gly Val Gly His Glu Leu Pro Leu Val Val Gln Ile 
    130                 135                 140


Asn Asn Gln Val Val Gln Leu Leu Leu Lys Pro Val Leu Gly Leu Phe 
145                 150                 155                 160


Gln Phe Ile Ile Ser Gly Arg Leu Leu Leu Val Leu Leu Gly Glu Val 
                165                 170                 175


Leu Asp Leu Leu Leu Glu Pro Leu Leu Pro Leu Phe Gln Ser Phe His 
            180                 185                 190


Gly Ala Gly Lys Val Leu Gln Leu Leu Leu Arg Val Gly Glu Leu Gln 
        195                 200                 205


Gly Gln Arg Pro Gly 
    210


<210>  8845
<211>  1202
<212>  DNA
<213>  Homo sapiens

<400>  8845
gtgccgtcca cgcccattgc tcaccgagga cccagctcaa gtttaaacac acctgggagc     60

ttcagacgtg gcctggacga ctccaccggg gggacccccc tcacacctgc ggcccggata    120

tcagccctca acattgtggg agacctactg cggaaagtcg gggcactgga gtccaaactc    180

gcttcctgcc ggaacctcgt gtacgatcag tccccaaacc gaacaggtgg cccagcctct    240

gggcggagca gcaagaacag agatggcggg gagagacggc caagcagcac cagcgtgcct    300

ttgggtgata aggggttggg gaagcgcctg gaatttggga agccgccttc acacatgtct    360

tcatcgccgc tgccgtcagc ccagggggta gtcaagatgt tgctttagga aaaccacgga    420

agctgaaggt cttggtgttg gtgcggaagt cgttaccttt tgtcgtcttt ttacactagg    480

tttttgtttt aagttagttt gagaaataag agcagtcacc atagttagtt agctttgcgg    540

cccaagccaa tgaccgaggc catcacctgt gctctggggt ttgtccctgg gaaatgtctt    600

ttcatcctta cctgccaccg tgtgcattgc aaagagggac aaaaggggct ctctgggaag    660

ggctctaagt tgtcggtgat gaggctaccg tgttgttttt gagatagagt cttgctctgt    720

cacccaggct ggagtgtggt ggcgtgatct cagctcactg caacctccgc ctcctgggtt    780

caaacggttc ttgttcctga gtcttccagg tagctgggat tacaggcacc caccaccaca    840

cctggctgaa ttttttgtat ttttaataga gacggggttt tgccatgttg cccagtgtgg    900

tcttgaactc ctggcctcaa gtgatcctcc catctcggcc tcccagaatg ctgggatttc    960

aagcatgagc catcgttccc atgccccatt gtgttgcact aacccaagcg gaggtcctga   1020

ttggtctttt tttttttttt cttttttgag acagagtcat gctcttgccc tgtcttgtcc   1080

aggctggagt gtagtggtgc aatttcggct caccgcagcc tccgcctcct aggttcaagc   1140

gattctctta tctcagcttc ccaagtagct gggactacag gagtgtgcca ctacacccac   1200

ta                                                                  1202


<210>  8846
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  8846

Met Ala Gly Arg Asp Gly Gln Ala Ala Pro Ala Cys Leu Trp Val Ile 
1               5                   10                  15


Arg Gly Trp Gly Ser Ala Trp Asn Leu Gly Ser Arg Leu His Thr Cys 
            20                  25                  30


Leu His Arg Arg Cys Arg Gln Pro Arg Gly 
        35                  40


<210>  8847
<211>  2336
<212>  DNA
<213>  Homo sapiens

<400>  8847
attgagattt ctagaggtga gttttcagat taattttcca ggcgatcttc ccaccttgac     60

ctcccaagtg ctgggggtta caagcgttag caatcatgcc tggccttttt ttttttttgg    120

agacagggtc tcactctgtc acccaggcta gactgcggtg gtgtgatctc ggctcactgc    180

aacctccgcc tcctgggctc cagcgatcct tccacctcag cctaccaagt agctgggact    240

acacatgcag gccaccacac ccagctaatt tttgtttgca tttttcatag agacagggtc    300

tcactatgtt gcgtaggctg taaaacaaac aaacaatagg taagagatgg atttttctag    360

tgggtctgag actgggcgtt ttgtgtgacc ttggaatctg agagccaggt agccagtgtc    420

ctcttcttca tttcacagga gagaaaattg agaccctgtg agaccctgct cctgactctt    480

gatgttcacc cttataactc tctgggcccc ggtgctagcc agtttgtcac agctgttatg    540

tcagcttaat ttggtttgct ctgtctgaag gttggggaag cgcctggaat ttgggaagcc    600

gccttcacac atgtcttcat cgccgctgcc gtcagcccag ggggtagtca agatgttgct    660

ttaggaaaac cacggaagct gaaggtcttg gtgttggtgc ggaagtcgtt accttttgtc    720

gtctttttac actaggtttt tgttttaagt tagtttgaga aataagagca gtcaccatag    780

ttagttagct ttgcggccca agccaatgac cgaggccatc acctgtgctc tggggtttgt    840

ccctgggaaa tgtcttttca tccttacctg ccaccgtgtg cattgcaaag agggacaaaa    900

ggggctctct gggaagggct ctaagttgtc ggtgatgagg ctaccgtgtt gtttttgaga    960

tagagtcttg ctctgtcacc caggctggag tgtggtggcg tgatctcagc tcactgcaac   1020

ctccgcctcc tgggttcaaa cggttcttgt tcctgagtct tccaggtagc tgggattaca   1080

ggcacccacc accacacctg gctgaatttt ttgtattttt aatagagacg gggttttgcc   1140

atgttgccca gtgtggtctt gaactcctgg cctcaagtga tcctcccatc tcggcctccc   1200

agaatgctgg gatttcaagc atgagccatc gttcccatgc cccattgtgt tgcactaacc   1260

caagcggagg tcctgattgg tctttttttt ttttttcttt tttgagacag agtcatgctc   1320

ttgccctgtc ttgtccaggc tggagtgtag tggtgcaatt tcggctcacc gcagcctccg   1380

cctcctaggt tcaagcgatt ctcttatctc agcttcccaa gtagctggga ctacaggagt   1440

gtgccactac acccactaat tttgtatttt tagtgaaacc ccatctctac taaaaataca   1500

aaaaattagc tgggtgcagt ggtgcgtgcc tataattcca gctactccag atgttgaggc   1560

aggagagttg cttggacccg ggaggtggag ggtgcagtga gccaagattg cgctactgta   1620

ctccagcctg ggcaacagag tgagactccg tctccaaaaa aaaaaaaaaa ggtgtcataa   1680

acctctgaga ctgtagcctg cttcttagct tctcattgag attcctagag gtgcgttcga   1740

gttttcagag taattttcca gaccaaccag cgtcagtggg aaatctgacc tcttttggca   1800

aactgcgatc attcattttc ctgagtcccc tggtggggtg gggggaattc tgcctcagga   1860

ccctgagggg tctttggggc aagatggcct tggtaatgca gccactaaga acaggacttc   1920

attcaaaggc ataatgaagt aaccagggtg accatcaagt aaaattaaag cacaagatca   1980

ttgtaggagg cttccttgtc aaagacgtga acgtgggatt tccaacgcac catggtgtgt   2040

ccactcatca ctgcatgtta ggaactgctg tctctttggg acacgagtta aaagaacaca   2100

ctaatttctg gagtgtgcct gcagcttcac ggccttcatt ttgttactaa gttattttct   2160

ggaagaacag caaaaatttc aggttgaaaa cagaactttc caagtgctac tgaaattccg   2220

cagagaatta cgctgcgatg gtgggtttct taccctagaa acatcctaac ctgtatccac   2280

agaagatgtc cttttatttt tttaaaagat caataaaatc aagagaaacg aatgtt       2336


<210>  8848
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8848

Met Pro Gly Leu Phe Phe Phe Leu Glu Thr Gly Ser His Ser Val Thr 
1               5                   10                  15


Gln Ala Arg Leu Arg Trp Cys Asp Leu Gly Ser Leu Gln Pro Pro Pro 
            20                  25                  30


Pro Gly Leu Gln Arg Ser Phe His Leu Ser Leu Pro Ser Ser Trp Asp 
        35                  40                  45


Tyr Thr Cys Arg Pro Pro His Pro Ala Asn Phe Cys Leu His Phe Ser 
    50                  55                  60


<210>  8849
<211>  2979
<212>  DNA
<213>  Homo sapiens

<400>  8849
attgagattt ctagaggtga gttttcagat taattttcca ggcgatcttc ccaccttgac     60

ctcccaagtg ctgggggtta caagcgttag caatcatgcc tggccttttt ttttttttgg    120

agacagggtc tcactctgtc acccaggcta gactgcggtg gtgtgatctc ggctcactgc    180

aacctccgcc tcctgggctc cagcgatcct tccacctcag cctaccaagt agctgggact    240

acacatgcag gccaccacac ccagctaatt tttgtttgca tttttcatag agacagggtc    300

tcactatgtt gcgtaggctg taaaacaaac aaacaatagg taagagatgg atttttctag    360

tgggtctgag actgggcgtt ttgtgtgacc ttggaatctg agagccaggt agccagtgtc    420

ctcttcttca tttcacagga gagaaaattg agaccctgtg agaccctgct cctgactctt    480

gatgttcacc cttataactc tctgggcccc ggtgctagcc agtttgtcac agctgttatg    540

tcagcttaat ttggtttgct ctgtctgaag gttggggaag cgcctggaat ttgggaagcc    600

gccttcacac atgtcttcat cgccgctgcc gtcagcccag ggggtagtca agatgttgct    660

ttaggaaaac cacggaagct gaaggtcttg gtgttggtgc ggaagtcgtt accttttgtc    720

gtctttttac actaggtttt tgttttaagt tagtttgaga aataagagca gtcaccatag    780

ttagttagct ttgcggccca agccaatgac cgaggccatc acctgtgctc tggggtttgt    840

ccctgggaaa tgtcttttca tccttacctg ccaccgtgtg cattgcaaag agggacaaaa    900

ggggctctct gggaagggct ctaagttgtc ggtgatgagg ctaccgtgtt gtttttgaga    960

tagagtcttg ctctgtcacc caggctggag tgtggtggcg tgatctcagc tcactgcaac   1020

ctccgcctcc tgggttcaaa cggttcttgt tcctgagtct tccaggtagc tgggattaca   1080

ggcacccacc accacacctg gctgaatttt ttgtattttt aatagagacg gggttttgcc   1140

atgttgccca gtgtggtctt gaactcctgg cctcaagtga tcctcccatc tcggcctccc   1200

agaatgctgg gatttcaagc atgagccatc gttcccatgc cccattgtgt tgcactaacc   1260

caagcggagg tcctgattgg tctttttttt ttttttcttt tttgagacag agtcatgctc   1320

ttgccctgtc ttgtccaggc tggagtgtag tggtgcaatt tcggctcacc gcagcctccg   1380

cctcctaggt tcaagcgatt ctcttatctc agcttcccaa gtagctggga ctacaggagt   1440

gtgccactac acccactaat tttgtatttt tagtgaaacc ccatctctac taaaaataca   1500

aaaaattagc tgggtgcagt ggtgcgtgcc tataattcca gctactccag atgttgaggc   1560

aggagagttg cttggacccg ggaggtggag ggtgcagtga gccaagattg cgctactgta   1620

ctccagcctg ggcaacagag tgagactccg tctccaaaaa aaaaaaaaaa ggtgtcataa   1680

acctctgaga ctgtagcctg cttcttagct tctcattgag attcctagag gtgcgttcga   1740

gttttcagag taattttcca gaccaaccag cgtcagtggg aaatctgacc tcttttggca   1800

aactgcgatc attcattttc ctgagtcccc tggtggggtg gggggaattc tgcctcagga   1860

ccctgagggg tctttggggc aagatggcct tggtaatgca gccactaaga acaggacttc   1920

attcaaaggc ataatgaagt aaccagggtg accatcaagt aaaattaaag cacaagatca   1980

ttgtaggagg cttccttgtc aaagacgtga acgtgggatt tccaacgcac catggtgtgt   2040

ccactcatca ctgcatgtta ggaactgctg tctctttggg acacgagtta aaagaacaca   2100

ctaatttctg gagtgtgcct gcagcttcac ggccttcatt ttgttactaa gttattttct   2160

ggaagaacag caaaaatttc aggttgaaaa cagaactttc caagtgctac tgaaattccg   2220

cagagaatta cgctgcgatg gtgggtttct taccctagaa acatcctaac ctgtatccac   2280

agaagatgtc cttttatttt tttaaaagat caataaaatc aagagaaacg aatgttgaac   2340

ttgttgggct tctggtcaaa gaggctttgt atgtttatac tttaatgttt tcccacagag   2400

tggtgaaaaa ctttttttaa ccaagttaaa aaatatgaaa aaatcttttt gaaaatttct   2460

attcaagcca ggtttttaga aatgtatccg ggatgtgttt gtgcgtcatt caaggcatat   2520

tagcatctgg tcacaagatg gagtcctttg tttccatgtt tcctgtctcc caaatctgtc   2580

tgatcccatg gagttggtgg tatacggcat cgtttgtgtt gaacagagcc tttgcaggca   2640

tgtctgtcta aaacactcaa gctgaaagaa ggacagggcc tacagcttgt ttttatggcc   2700

cttactctaa gaatgattta ttatgttttt aagggttgtt ttaaagaaga tgaatattcg   2760

gcaagaccat atgtagcctg taaaggctaa aatactatct ggctgggtgg gtggtggtgg   2820

tggtgtgaga gacaaggtgt tactgttacc taggctgcag tgcagtggcg tgatcatagc   2880

tcactgcagc ctggaactcc tggctcacat gatcctcctg ccttagcctt ccaagaggtt   2940

gggagtacag gtgtgcacta tcctgcctgg cttactaac                          2979


<210>  8850
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  8850

Met Pro Gly Leu Phe Phe Phe Leu Glu Thr Gly Ser His Ser Val Thr 
1               5                   10                  15


Gln Ala Arg Leu Arg Trp Cys Asp Leu Gly Ser Leu Gln Pro Pro Pro 
            20                  25                  30


Pro Gly Leu Gln Arg Ser Phe His Leu Ser Leu Pro Ser Ser Trp Asp 
        35                  40                  45


Tyr Thr Cys Arg Pro Pro His Pro Ala Asn Phe Cys Leu His Phe Ser 
    50                  55                  60


<210>  8851
<211>  1166
<212>  DNA
<213>  Homo sapiens

<400>  8851
ttcaccctta taactctctg ggccccggtg ctagccagtt tgtcacagct gttatgtcag     60

cttaatttgg tttgctctgt ctgaaggttg gggaagcgcc tggaatttgg gaagccgcct    120

tcacacatgt cttcatcgcc gctgccgtca gcccaggggg tagtcaagat gttgctttag    180

gaaaaccacg gaagctgaag gtcttggtgt tggtgcggaa gtcgttacct tttgtcgtct    240

ttttacacta ggtttttgtt ttaagttagt ttgagaaata agagcagtca ccatagttag    300

ttagctttgc ggcccaagcc aatgaccgag gccatcacct gtgctctggg gtttgtccct    360

gggaaatgtc ttttcatcct tacctgccac cgtgtgcatt gcaaagaggg acaaaagggg    420

ctctctggga agggctctaa gttgtcggtg atgaggctac cgtgttgttt tgagactccg    480

tctccaaaaa aaaaaaaaaa ggtgtcataa acctctgaga ctgtagcctg cttcttagct    540

tctcattgag attcctagag gtgcgttcga gttttcagag taattttcca gaccaaccag    600

cgtcagtggg aaatctgacc tcttttggca aactgcgatc attcattttc ctgagtcccc    660

tggtggggtg gggggaattc tgcctcagga ccctgagggg tctttggggc aagatggcct    720

tggtaatgca gccactaaga acaggacttc attcaaaggc ataatgaagt aaccagggtg    780

accatcaagt aaaattaaag cacaagatca ttgtaggagg cttccttgtc aaagacgtga    840

acgtgggatt tccaacgcac catggtgtgt ccactcatca ctgcatgtta ggaactgctg    900

tctctttggg acacgagtta aaagaacaca ctaatttctg gagtgtgcct gcagcttcac    960

ggccttcatt ttgttactaa gttattttct ggaagaacag caaaaatttc aggttgaaaa   1020

cagaactttc caagtgctac tgaaattccg cagagaatta cgctgcgatg gtgggtttct   1080

taccctagaa acatcctaac ctgtatccac agaagatgtc cttttatttt tttaaaagat   1140

caataaaatc aagagaaacg aatgtt                                        1166


<210>  8852
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  8852

Met Thr Glu Ala Ile Thr Cys Ala Leu Gly Phe Val Pro Gly Lys Cys 
1               5                   10                  15


Leu Phe Ile Leu Thr Cys His Arg Val His Cys Lys Glu Gly Gln Lys 
            20                  25                  30


Gly Leu Ser Gly Lys Gly Ser Lys Leu Ser Val Met Arg Leu Pro Cys 
        35                  40                  45


Cys Phe Glu Thr Pro Ser Pro Lys Lys Lys Lys Lys Val Ser 
    50                  55                  60


<210>  8853
<211>  1809
<212>  DNA
<213>  Homo sapiens

<400>  8853
ttcaccctta taactctctg ggccccggtg ctagccagtt tgtcacagct gttatgtcag     60

cttaatttgg tttgctctgt ctgaaggttg gggaagcgcc tggaatttgg gaagccgcct    120

tcacacatgt cttcatcgcc gctgccgtca gcccaggggg tagtcaagat gttgctttag    180

gaaaaccacg gaagctgaag gtcttggtgt tggtgcggaa gtcgttacct tttgtcgtct    240

ttttacacta ggtttttgtt ttaagttagt ttgagaaata agagcagtca ccatagttag    300

ttagctttgc ggcccaagcc aatgaccgag gccatcacct gtgctctggg gtttgtccct    360

gggaaatgtc ttttcatcct tacctgccac cgtgtgcatt gcaaagaggg acaaaagggg    420

ctctctggga agggctctaa gttgtcggtg atgaggctac cgtgttgttt tgagactccg    480

tctccaaaaa aaaaaaaaaa ggtgtcataa acctctgaga ctgtagcctg cttcttagct    540

tctcattgag attcctagag gtgcgttcga gttttcagag taattttcca gaccaaccag    600

cgtcagtggg aaatctgacc tcttttggca aactgcgatc attcattttc ctgagtcccc    660

tggtggggtg gggggaattc tgcctcagga ccctgagggg tctttggggc aagatggcct    720

tggtaatgca gccactaaga acaggacttc attcaaaggc ataatgaagt aaccagggtg    780

accatcaagt aaaattaaag cacaagatca ttgtaggagg cttccttgtc aaagacgtga    840

acgtgggatt tccaacgcac catggtgtgt ccactcatca ctgcatgtta ggaactgctg    900

tctctttggg acacgagtta aaagaacaca ctaatttctg gagtgtgcct gcagcttcac    960

ggccttcatt ttgttactaa gttattttct ggaagaacag caaaaatttc aggttgaaaa   1020

cagaactttc caagtgctac tgaaattccg cagagaatta cgctgcgatg gtgggtttct   1080

taccctagaa acatcctaac ctgtatccac agaagatgtc cttttatttt tttaaaagat   1140

caataaaatc aagagaaacg aatgttgaac ttgttgggct tctggtcaaa gaggctttgt   1200

atgtttatac tttaatgttt tcccacagag tggtgaaaaa ctttttttaa ccaagttaaa   1260

aaatatgaaa aaatcttttt gaaaatttct attcaagcca ggtttttaga aatgtatccg   1320

ggatgtgttt gtgcgtcatt caaggcatat tagcatctgg tcacaagatg gagtcctttg   1380

tttccatgtt tcctgtctcc caaatctgtc tgatcccatg gagttggtgg tatacggcat   1440

cgtttgtgtt gaacagagcc tttgcaggca tgtctgtcta aaacactcaa gctgaaagaa   1500

ggacagggcc tacagcttgt ttttatggcc cttactctaa gaatgattta ttatgttttt   1560

aagggttgtt ttaaagaaga tgaatattcg gcaagaccat atgtagcctg taaaggctaa   1620

aatactatct ggctgggtgg gtggtggtgg tggtgtgaga gacaaggtgt tactgttacc   1680

taggctgcag tgcagtggcg tgatcatagc tcactgcagc ctggaactcc tggctcacat   1740

gatcctcctg ccttagcctt ccaagaggtt gggagtacag gtgtgcacta tcctgcctgg   1800

cttactaac                                                           1809


<210>  8854
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  8854

Met Thr Glu Ala Ile Thr Cys Ala Leu Gly Phe Val Pro Gly Lys Cys 
1               5                   10                  15


Leu Phe Ile Leu Thr Cys His Arg Val His Cys Lys Glu Gly Gln Lys 
            20                  25                  30


Gly Leu Ser Gly Lys Gly Ser Lys Leu Ser Val Met Arg Leu Pro Cys 
        35                  40                  45


Cys Phe Glu Thr Pro Ser Pro Lys Lys Lys Lys Lys Val Ser 
    50                  55                  60


<210>  8855
<211>  759
<212>  DNA
<213>  Homo sapiens

<400>  8855
cagggggtag tcaagatgtt gctttaggaa aaccacggaa gctgaaggtc ttggtgttgg     60

tgcggaagtc gttacctttt gtcgtctttt tacactaggt ttttgtttta agttagtttg    120

agaaataaga gcagtcacca tagttagtta gctttgcggc ccaagccaat gaccgaggcc    180

atcacctgtg ctctggggtt tgtccctggg aaatgtcttt tcatccttac ctgccaccgt    240

gtgcattgca aagagggaca aaaggggctc tctgggaagg gctctaagtt gtcggtgatg    300

aggctaccgt gttgtttttg agatagagtc ttgctctgtc acccaggctg gagtgtggtg    360

gcgtgatctc agctcactgc aacctccgcc tcctgggttc aaacggttct tgttcctata    420

attccagcta ctccagatgt tgaggcagga gagttgcttg gacccgggag gtggagggtg    480

cagtgagcca agattgcgct actgtactcc agcctgggca acagagtgag actccgtctc    540

caaaaaaaaa aaaaaaggtg tcataaacct ctgagactgt agcctgcttc ttagcttctc    600

attgagattc ctagaggtgc gttcgagttt tcagagtaat tttccagacc aaccagcgtc    660

agtgggaaat ctgacctctt ttggcaaact gcgatcattc attttcctga gtcccctggt    720

ggggtggggg gaattctgcc tcaggaccct gaggggtct                           759


<210>  8856
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  8856

Met Thr Glu Ala Ile Thr Cys Ala Leu Gly Phe Val Pro Gly Lys Cys 
1               5                   10                  15


Leu Phe Ile Leu Thr Cys His Arg Val His Cys Lys Glu Gly Gln Lys 
            20                  25                  30


Gly Leu Ser Gly Lys Gly Ser Lys Leu Ser Val Met Arg Leu Pro Cys 
        35                  40                  45


Cys Phe 
    50


<210>  8857
<211>  1129
<212>  DNA
<213>  Homo sapiens

<400>  8857
gtttttttcc tattctaaat caaagaccac agcagaccag aatcctgtgg cttctcaaat     60

gaccaagcct gacatattga aaagcagatc gtcttgcttt gaaaaacctt ctccacccac    120

ccccgcaacc aatttcagct gattaaattc aatcactcat gccttaagac tggcaatgat    180

ttgttgactt caacttgaat atctgcatct tatttgtgcc gtgtgtgttt tctgccataa    240

aaaaaattta tattgcaata ggactatagc tacaagttta aaatagattt ataaaaaatc    300

tatcccaacc atgaagattt ctttgctaaa taatgtgttt tcttacaacc cacaggcgag    360

gaaacgagac ctctttcgtt ccttctagaa ggtctggagg acgtagagtt attgaaaatg    420

cagatggttc tgaggaggaa acggacactc gagacgcaga cttcaatgga accaaggcca    480

gtgaataagc aactttctac agttttgcac cacggcaaga aaaccaaaaa ccaaaacaaa    540

caaacaaaaa aaacccaaca acaacccaga acaaagcaaa acccagcaga ctgtacttag    600

cattgtctaa atccattctc aaattccaaa tatcacagac acccctcaca caaggaatat    660

aaaaaccacc accccctact acccctgtat tcaaggtaaa aattgaagtt tgtatgatgt    720

aagagatgag aaaaacccaa caggaaacac agacacatcc tccagttcta tcaatggatt    780

gtgcagacac tgagttttta gaaaaacata tccacggtaa ccggtccctg gcaattctgt    840

ttacatgaaa tggggagaaa gtcaccgaaa tgggtgccgc cggcccccac tcccaattca    900

ttccctaacc tgcaaacctt tccaacttct cacgtcaggc ctttgagaat tctttccccc    960

tctcctggtt tccacacctc agacacgcac agttcaccaa gtgccttctg tagtcacatg   1020

aattgaaaag gagacgctgc tcccacggag gggagcagga atgctgcact gtttacaccc   1080

tgactgtgct taaaaacact ttcactaata aatggttata aatcacaat               1129


<210>  8858
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  8858

Met Gln Met Val Leu Arg Arg Lys Arg Thr Leu Glu Thr Gln Thr Ser 
1               5                   10                  15


Met Glu Pro Arg Pro Val Asn Lys Gln Leu Ser Thr Val Leu His His 
            20                  25                  30


Gly Lys Lys Thr Lys Asn Gln Asn Lys Gln Thr Lys Lys Thr Gln Gln 
        35                  40                  45


Gln Pro Arg Thr Lys Gln Asn Pro Ala Asp Cys Thr 
    50                  55                  60


<210>  8859
<211>  1148
<212>  DNA
<213>  Homo sapiens

<400>  8859
agttagcgga tggcatgccc ggaagccatc tgaaatcacc tctagagttt ggggaccact     60

gcgtgagaca gggaaaagtc caaacccctc tgagaagggg aagagagcag ctggcgcagg    120

gcaccaagcc ttcagggaaa agccccactc gctgcatggc gaggaaacga gacctctttc    180

gttccttcta gaaggtctgg aggacgtaga gttattgaaa atgcagatgg ttctgaggag    240

gaaacggaca ctcgagacgc agacttcaat ggaaccaagg ccagtgaata agcaactttc    300

tacagttttg caccacggca agaaaaccaa aaaccaaaac aaacaaacaa aaaaaaccca    360

acaacaaccc agaacaaagc aaaacccagc agactgtact tagcattgtc taaatccatt    420

ctcaaattcc aaatatcaca gacacccctc acacaaggaa tataaaaacc accaccctcc    480

agcctgggca acgtagtaaa acctcatcta tacaagaatt taaaaataag ctgggcgtgg    540

tggtacacac ctgtggtccc agctactagg gaggctgagc caggaagaac gctccagccc    600

aggacttcga ggctgcaatg agctataatt gcatcattgc actccagcct gggcaacaga    660

gaccctgtct caaccaccac caccaccacc acccctacta cccctgtatt caaggtaaaa    720

attgaagttt gtatgatgta agagatgaga aaaacccaac aggaaacaca gacacatcct    780

ccagttctat caatggattg tgcagacact gagtttttag aaaaacatat ccacggtaac    840

cggtccctgg caattctgtt tacatgaaat ggggagaaag tcaccgaaat gggtgccgcc    900

ggcccccact cccaattcat tccctaacct gcaaaccttt ccaacttctc acgtcaggcc    960

tttgagaatt ctttccccct ctcctggttt ccacacctca gacacgcaca gttcaccaag   1020

tgccttctgt agtcacatga attgaaaagg agacgctgct cccacggagg ggagcaggaa   1080

tgctgcactg tttacaccct gactgtgctt aaaaacactt tcactaataa atggttataa   1140

atcacaat                                                            1148


<210>  8860
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  8860

Met Pro Gly Ser His Leu Lys Ser Pro Leu Glu Phe Gly Asp His Cys 
1               5                   10                  15


Val Arg Gln Gly Lys Val Gln Thr Pro Leu Arg Arg Gly Arg Glu Gln 
            20                  25                  30


Leu Ala Gln Gly Thr Lys Pro Ser Gly Lys Ser Pro Thr Arg Cys Met 
        35                  40                  45


Ala Arg Lys Arg Asp Leu Phe Arg Ser Phe 
    50                  55


<210>  8861
<211>  1635
<212>  DNA
<213>  Homo sapiens

<400>  8861
tatgttgtct gctatgtgtc ttctttcact tggcaagaat tccaggctca tccatgctgt     60

ggcatgcatt gatactttat tccttttcat ggctgaatac tattccacca tctgactgat    120

tcttgagagg agtccagata cggggctcag gaaagcactc aagatgccac ctccaggtga    180

cacaccagct acaaggggtg ccaccctccg ctgaaaccac ctgttttcct tgctgtttgc    240

agagagaaac aggcggccac caagtcgctg aagcagaaag acaagaagct gaaggaaatc    300

ttgctgcagg tggaggacga gcgcaagatg gccgagcagt acaaggagca ggtagcccct    360

gccacccagc ctccctcgag cccccagccc ccagccggcc tcccctaacc acccctccaa    420

ctctccgcga caggcagaga aaggcaatgc cagggtcaag cagctcaaga ggcagctgga    480

ggaggcagag gaggagtccc agcgcatcaa cgccaaccgc aggaagctgc agcgggagct    540

ggatgaggcc acggagagca acgaggccat gggccgcgag gtgaacgcac tcaagagcaa    600

gctcagaggg ccccccccac aggaaacttc gcagtgatgc accaggcgag gaaacgagac    660

ctctttcgtt ccttctagaa ggtctggagg acgtagagtt attgaaaatg cagatggttc    720

tgaggaggaa acggacactc gagacgcaga cttcaatgga accaaggcca gtgaataagc    780

aactttctac agttttgcac cacggcaaga aaaccaaaaa ccaaaacaaa caaacaaaaa    840

aaacccaaca acaacccaga acaaagcaaa acccagcaga ctgtacttag cattgtctaa    900

atccattctc aaattccaaa tatcacagac acccctcaca caaggaatat aaaaaccacc    960

accctccagc ctgggcaacg tagtaaaacc tcatctatac aagaatttaa aaataagctg   1020

ggcgtggtgg tacacacctg tggtcccagc tactagggag gctgagccag gaagaacgct   1080

ccagcccagg acttcgaggc tgcaatgagc tataattgca tcattgcact ccagcctggg   1140

caacagagac cctgtctcaa ccaccaccac caccaccacc cctactaccc ctgtattcaa   1200

ggtaaaaatt gaagtttgta tgatgtaaga gatgagaaaa acccaacagg aaacacagac   1260

acatcctcca gttctatcaa tggattgtgc agacactgag tttttagaaa aacatatcca   1320

cggtaaccgg tccctggcaa ttctgtttac atgaaatggg gagaaagtca ccgaaatggg   1380

tgccgccggc ccccactccc aattcattcc ctaacctgca aacctttcca acttctcacg   1440

tcaggccttt gagaattctt tccccctctc ctggtttcca cacctcagac acgcacagtt   1500

caccaagtgc cttctgtagt cacatgaatt gaaaaggaga cgctgctccc acggagggga   1560

gcaggaatgc tgcactgttt acaccctgac tgtgcttaaa aacactttca ctaataaatg   1620

gttataaatc acaat                                                    1635


<210>  8862
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  8862

Met Gln Met Val Leu Arg Arg Lys Arg Thr Leu Glu Thr Gln Thr Ser 
1               5                   10                  15


Met Glu Pro Arg Pro Val Asn Lys Gln Leu Ser Thr Val Leu His His 
            20                  25                  30


Gly Lys Lys Thr Lys Asn Gln Asn Lys Gln Thr Lys Lys Thr Gln Gln 
        35                  40                  45


Gln Pro Arg Thr Lys Gln Asn Pro Ala Asp Cys Thr 
    50                  55                  60


<210>  8863
<211>  1596
<212>  DNA
<213>  Homo sapiens

<400>  8863
tatgttgtct gctatgtgtc ttctttcact tggcaagaat tccaggctca tccatgctgt     60

ggcatgcatt gatactttat tccttttcat ggctgaatac tattccacca tctgactgat    120

tcttgagagg agtccagata cggggctcag gaaagcactc aagatgccac ctccaggtga    180

cacaccagct acaaggggtg ccaccctccg ctgaaaccac ctgttttcct tgctgtttgc    240

agagagaaac aggcggccac caagtcgctg aagcagaaag acaagaagct gaaggaaatc    300

ttgctgcagg tggaggacga gcgcaagatg gccgagcagt acaaggagca ggtagcccct    360

gccacccagc ctccctcgag cccccagccc ccagccggcc tcccctaacc acccctccaa    420

ctctccgcga caggcagaga aaggcaatgc cagggtcaag cagctcaaga ggcagctgga    480

ggaggcagag gaggagtccc agcgcatcaa cgccaaccgc aggaagctgc agcgggagct    540

ggatgaggcc acggagagca acgaggccat gggccgcgag gtgaacgcac tcaagagcaa    600

gctcaggcga ggaaacgaga cctctttcgt tccttctaga aggtctggag gacgtagagt    660

tattgaaaat gcagatggtt ctgaggagga aacggacact cgagacgcag acttcaatgg    720

aaccaaggcc agtgaataag caactttcta cagttttgca ccacggcaag aaaaccaaaa    780

accaaaacaa acaaacaaaa aaaacccaac aacaacccag aacaaagcaa aacccagcag    840

actgtactta gcattgtcta aatccattct caaattccaa atatcacaga cacccctcac    900

acaaggaata taaaaaccac caccctccag cctgggcaac gtagtaaaac ctcatctata    960

caagaattta aaaataagct gggcgtggtg gtacacacct gtggtcccag ctactaggga   1020

ggctgagcca ggaagaacgc tccagcccag gacttcgagg ctgcaatgag ctataattgc   1080

atcattgcac tccagcctgg gcaacagaga ccctgtctca accaccacca ccaccaccac   1140

ccctactacc cctgtattca aggtaaaaat tgaagtttgt atgatgtaag agatgagaaa   1200

aacccaacag gaaacacaga cacatcctcc agttctatca atggattgtg cagacactga   1260

gtttttagaa aaacatatcc acggtaaccg gtccctggca attctgttta catgaaatgg   1320

ggagaaagtc accgaaatgg gtgccgccgg cccccactcc caattcattc cctaacctgc   1380

aaacctttcc aacttctcac gtcaggcctt tgagaattct ttccccctct cctggtttcc   1440

acacctcaga cacgcacagt tcaccaagtg ccttctgtag tcacatgaat tgaaaaggag   1500

acgctgctcc cacggagggg agcaggaatg ctgcactgtt tacaccctga ctgtgcttaa   1560

aaacactttc actaataaat ggttataaat cacaat                             1596


<210>  8864
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  8864

Met Gly Arg Glu Val Asn Ala Leu Lys Ser Lys Leu Arg Arg Gly Asn 
1               5                   10                  15


Glu Thr Ser Phe Val Pro Ser Arg Arg Ser Gly Gly Arg Arg Val Ile 
            20                  25                  30


Glu Asn Ala Asp Gly Ser Glu Glu Glu Thr Asp Thr Arg Asp Ala Asp 
        35                  40                  45


Phe Asn Gly Thr Lys Ala Ser Glu 
    50                  55


<210>  8865
<211>  1484
<212>  DNA
<213>  Homo sapiens

<400>  8865
caggccgagc agctcagcaa cgagctggcc acagagcgca gcacggccca gaagaatgag     60

agtgcccggc agcagctcga gcggcagaac aaggagctcc ggagcaagct ccacgagatg    120

gagggggccg tcaagtccaa gttcaagtcc accatcgcgg cgctggaggc caagattgca    180

cagctggagg agcaggtcga gcaggaggcc agagagaaac aggcggccac caagtcgctg    240

aagcagaaag acaagaagct gaaggaaatc ttgctgcagg tggaggacga gcgcaagatg    300

gccgagcagt acaaggagca ggcagagaaa ggcaatgcca gggtcaagca gctcaagagg    360

cagctggagg aggcagagga ggagtcccag cgcatcaacg ccaaccgcag gaagctgcag    420

cgggagctgg atgaggccac ggagagcaac gaggccatgg gccgcgaggt gaacgcactc    480

aagagcaagc tcaggcgagg aaacgagacc tctttcgttc cttctagaag gtctggagga    540

cgtagagtta ttgaaaatgc agatggttct gaggaggaaa cggacactcg agacgcagac    600

ttcaatggaa ccaaggccag tgaataagca actttctaca gttttgcacc acggcaagaa    660

aaccaaaaac caaaacaaac aaacaaaaaa aacccaacaa caacccagaa caaagcaaaa    720

cccagcagac tgtacttagc attgtctaaa tccattctca aattccaaat atcacagaca    780

cccctcacac aaggaatata aaaaccacca ccctccagcc tgggcaacgt agtaaaacct    840

catctataca agaatttaaa aataagctgg gcgtggtggt acacacctgt ggtcccagct    900

actagggagg ctgagccagg aagaacgctc cagcccagga cttcgaggct gcaatgagct    960

ataattgcat cattgcactc cagcctgggc aacagagacc ctgtctcaac caccaccacc   1020

accaccaccc ctactacccc tgtattcaag gtaaaaattg aagtttgtat gatgtaagag   1080

atgagaaaaa cccaacagga aacacagaca catcctccag ttctatcaat ggattgtgca   1140

gacactgagt ttttagaaaa acatatccac ggtaaccggt ccctggcaat tctgtttaca   1200

tgaaatgggg agaaagtcac cgaaatgggt gccgccggcc cccactccca attcattccc   1260

taacctgcaa acctttccaa cttctcacgt caggcctttg agaattcttt ccccctctcc   1320

tggtttccac acctcagaca cgcacagttc accaagtgcc ttctgtagtc acatgaattg   1380

aaaaggagac gctgctccca cggaggggag caggaatgct gcactgttta caccctgact   1440

gtgcttaaaa acactttcac taataaatgg ttataaatca caat                    1484


<210>  8866
<211>  169
<212>  PRT
<213>  Homo sapiens

<400>  8866

Met Glu Gly Ala Val Lys Ser Lys Phe Lys Ser Thr Ile Ala Ala Leu 
1               5                   10                  15


Glu Ala Lys Ile Ala Gln Leu Glu Glu Gln Val Glu Gln Glu Ala Arg 
            20                  25                  30


Glu Lys Gln Ala Ala Thr Lys Ser Leu Lys Gln Lys Asp Lys Lys Leu 
        35                  40                  45


Lys Glu Ile Leu Leu Gln Val Glu Asp Glu Arg Lys Met Ala Glu Gln 
    50                  55                  60


Tyr Lys Glu Gln Ala Glu Lys Gly Asn Ala Arg Val Lys Gln Leu Lys 
65                  70                  75                  80


Arg Gln Leu Glu Glu Ala Glu Glu Glu Ser Gln Arg Ile Asn Ala Asn 
                85                  90                  95


Arg Arg Lys Leu Gln Arg Glu Leu Asp Glu Ala Thr Glu Ser Asn Glu 
            100                 105                 110


Ala Met Gly Arg Glu Val Asn Ala Leu Lys Ser Lys Leu Arg Arg Gly 
        115                 120                 125


Asn Glu Thr Ser Phe Val Pro Ser Arg Arg Ser Gly Gly Arg Arg Val 
    130                 135                 140


Ile Glu Asn Ala Asp Gly Ser Glu Glu Glu Thr Asp Thr Arg Asp Ala 
145                 150                 155                 160


Asp Phe Asn Gly Thr Lys Ala Ser Glu 
                165


<210>  8867
<211>  1523
<212>  DNA
<213>  Homo sapiens

<400>  8867
caggccgagc agctcagcaa cgagctggcc acagagcgca gcacggccca gaagaatgag     60

agtgcccggc agcagctcga gcggcagaac aaggagctcc ggagcaagct ccacgagatg    120

gagggggccg tcaagtccaa gttcaagtcc accatcgcgg cgctggaggc caagattgca    180

cagctggagg agcaggtcga gcaggaggcc agagagaaac aggcggccac caagtcgctg    240

aagcagaaag acaagaagct gaaggaaatc ttgctgcagg tggaggacga gcgcaagatg    300

gccgagcagt acaaggagca ggcagagaaa ggcaatgcca gggtcaagca gctcaagagg    360

cagctggagg aggcagagga ggagtcccag cgcatcaacg ccaaccgcag gaagctgcag    420

cgggagctgg atgaggccac ggagagcaac gaggccatgg gccgcgaggt gaacgcactc    480

aagagcaagc tcagagggcc ccccccacag gaaacttcgc agtgatgcac caggcgagga    540

aacgagacct ctttcgttcc ttctagaagg tctggaggac gtagagttat tgaaaatgca    600

gatggttctg aggaggaaac ggacactcga gacgcagact tcaatggaac caaggccagt    660

gaataagcaa ctttctacag ttttgcacca cggcaagaaa accaaaaacc aaaacaaaca    720

aacaaaaaaa acccaacaac aacccagaac aaagcaaaac ccagcagact gtacttagca    780

ttgtctaaat ccattctcaa attccaaata tcacagacac ccctcacaca aggaatataa    840

aaaccaccac cctccagcct gggcaacgta gtaaaacctc atctatacaa gaatttaaaa    900

ataagctggg cgtggtggta cacacctgtg gtcccagcta ctagggaggc tgagccagga    960

agaacgctcc agcccaggac ttcgaggctg caatgagcta taattgcatc attgcactcc   1020

agcctgggca acagagaccc tgtctcaacc accaccacca ccaccacccc tactacccct   1080

gtattcaagg taaaaattga agtttgtatg atgtaagaga tgagaaaaac ccaacaggaa   1140

acacagacac atcctccagt tctatcaatg gattgtgcag acactgagtt tttagaaaaa   1200

catatccacg gtaaccggtc cctggcaatt ctgtttacat gaaatgggga gaaagtcacc   1260

gaaatgggtg ccgccggccc ccactcccaa ttcattccct aacctgcaaa cctttccaac   1320

ttctcacgtc aggcctttga gaattctttc cccctctcct ggtttccaca cctcagacac   1380

gcacagttca ccaagtgcct tctgtagtca catgaattga aaaggagacg ctgctcccac   1440

ggaggggagc aggaatgctg cactgtttac accctgactg tgcttaaaaa cactttcact   1500

aataaatggt tataaatcac aat                                           1523


<210>  8868
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  8868

Met Glu Gly Ala Val Lys Ser Lys Phe Lys Ser Thr Ile Ala Ala Leu 
1               5                   10                  15


Glu Ala Lys Ile Ala Gln Leu Glu Glu Gln Val Glu Gln Glu Ala Arg 
            20                  25                  30


Glu Lys Gln Ala Ala Thr Lys Ser Leu Lys Gln Lys Asp Lys Lys Leu 
        35                  40                  45


Lys Glu Ile Leu Leu Gln Val Glu Asp Glu Arg Lys Met Ala Glu Gln 
    50                  55                  60


Tyr Lys Glu Gln Ala Glu Lys Gly Asn Ala Arg Val Lys Gln Leu Lys 
65                  70                  75                  80


Arg Gln Leu Glu Glu Ala Glu Glu Glu Ser Gln Arg Ile Asn Ala Asn 
                85                  90                  95


Arg Arg Lys Leu Gln Arg Glu Leu Asp Glu Ala Thr Glu Ser Asn Glu 
            100                 105                 110


Ala Met Gly Arg Glu Val Asn Ala Leu Lys Ser Lys Leu Arg Gly Pro 
        115                 120                 125


Pro Pro Gln Glu Thr Ser Gln 
    130                 135


<210>  8869
<211>  6923
<212>  DNA
<213>  Homo sapiens

<400>  8869
agggagattt ggacgctccg gcctgggagg tgcgtcagat ccgagctcgc catccagttt     60

cctctccact agtcccccca gttggagatc tgggaccaac aaggcaccat ggcgcagaag    120

ggccaactca gtgacgatga gaagttcctc tttgtggaca aaaacttcat caacagccca    180

gtggcccagg ctgactgggc cgccaagaga ctcgtctggg tcccctcgga gaagcagggc    240

ttcgaggcag ccagcattaa ggaggagaag ggggatgagg tggttgtgga gctggtggag    300

aatggcaaga aggtcacggt tgggaaagat gacatccaga agatgaaccc acccaagttc    360

tccaaggtgg aggacatggc ggagctgacg tgcctcaacg aagcctccgt gctacacaac    420

ctgagggagc ggtacttctc agggctaata tatacgtact ctggcctctt ctgcgtggtg    480

gtcaacccct ataaacacct gcccatctac tcggagaaga tcgtcgacat gtacaagggc    540

aagaagaggc acgagatgcc gcctcacatc tacgccatcg cagacacggc ctaccggagc    600

atgcttcaag atcgggagga ccagtccatt ctatgcacag gcgagtctgg agccgggaaa    660

accgaaaaca ccaagaaggt cattcagtac ctggccgtgg tggcctcctc ccacaagggc    720

aagaaagaca caagtatcac gggagagctg gaaaagcagc ttctacaagc aaacccgatt    780

ctggaggctt tcggcaacgc caaaacagtg aagaacgaca actcctcacg attcggcaaa    840

ttcatccgca tcaacttcga cgtcacgggt tacatcgtgg gagccaacat tgagacctat    900

ctgctagaaa aatcacgggc aattcgccaa gccagagacg agaggacatt ccacatcttt    960

tactacatga ttgctggagc caaggagaag atgagaagtg acttgctttt ggagggcttc   1020

aacaactaca ccttcctctc caatggcttt gtgcccatcc cagcagccca ggatgatgag   1080

atgttccagg aaaccgtgga ggccatggca atcatgggtt tcagcgagga ggagcagcta   1140

tccatattga aggtggtatc atcggtcctg cagcttggaa atatcgtctt caagaaggaa   1200

agaaacacag accaggcgtc catgccagat aacacagctg ctcagaaagt ttgccacctc   1260

atgggaatta atgtgacaga tttcaccaga tccatcctca ctcctcgtat caaggttggg   1320

cgagatgtgg tacagaaagc tcagacaaaa gaacaggctg actttgctgt agaggctttg   1380

gccaaggcaa catatgagcg ccttttccgc tggatactca cccgcgtgaa caaagccctg   1440

gacaagaccc atcggcaagg ggcttccttc ctggggatcc tggatatagc tggatttgag   1500

atctttgagg tgaactcctt cgagcagctg tgcatcaact acaccaacga gaagctgcag   1560

cagctcttca accacaccat gttcatcctg gagcaggagg agtaccagcg cgagggcatc   1620

gagtggaact tcatcgactt tgggctggac ctacagccct gcatcgagct catcgagcga   1680

ccgaacaacc ctccaggtgt gctggccctg ctggacgagg aatgctggtt ccccaaagcc   1740

acggacaagt ctttcgtgga gaagctgtgc acggagcagg gcagccaccc caagttccag   1800

aagcccaagc agctcaagga caagactgag ttctccatca tccattatgc tgggaaggtg   1860

gactataatg cgagtgcctg gctgaccaag aatatggacc cgctgaatga caacgtgact   1920

tccctgctca atgcctcctc cgacaagttt gtggccgacc tgtggaagga cgtggaccgc   1980

atcgtgggcc tggaccagat ggccaagatg acggagagct cgctgcccag cgcctccaag   2040

accaagaagg gcatgttccg cacagtgggg cagctgtaca aggagcagct gggcaagctg   2100

atgaccacgc tacgcaacac cacgcccaac ttcgtgcgct gcatcatccc caaccacgag   2160

aagaggtccg gcaagctgga tgcgttcctg gtgctggagc agctgcggtg caatggggtg   2220

ctggaaggca ttcgcatctg ccggcagggc ttccccaacc ggatcgtctt ccaggagttc   2280

cgccaacgct acgagatcct ggcggcgaat gccatcccca aaggcttcat ggacgggaag   2340

caggcctgca ttctcatgat caaagccctg gaacttgacc ccaacttata caggataggg   2400

cagagcaaaa tcttcttccg aactggcgtc ctggcccacc tagaggagga gcgagatttg   2460

aagatcaccg atgtcatcat ggccttccag gcgatgtgtc gtggctactt ggccagaaag   2520

gcttttgcca agaggcagca gcagctgacc gccatgaagg tgattcagag gaactgcgcc   2580

gcctacctca agctgcggaa ctggcagtgg tggaggcttt tcaccaaagt gaagccactg   2640

ctgcaggtga cacggcagga ggaggagatg caggccaagg aggatgaact gcagaagacc   2700

aaggagcggc agcagaaggc agagaatgag cttaaggagc tggaacagaa gcactcgcag   2760

ctgaccgagg agaagaacct gctacaggaa cagctgcagg cagagacaga gctgtatgca   2820

gaggctgagg agatgcgggt gcggctggcg gccaagaagc aggagctgga ggagatactg   2880

catgagatgg aggcccgcct ggaggaggag gaagacaggg gccagcagct acaggctgaa   2940

aggaagaaga tggcccagca gatgctggac cttgaagaac agctggagga ggaggaagct   3000

gccaggcaga agctgcaact tgagaaggtc acggctgagg ccaagatcaa gaaactggag   3060

gatgagatcc tggtcatgga tgatcagaac aataaactat caaaagaacg aaaactcctt   3120

gaggagagga ttagtgactt aacgacaaat cttgcagaag aggaagaaaa ggccaagaat   3180

cttaccaagc tgaaaaacaa gcatgaatct atgatttcag aactggaagt gcggctaaag   3240

aaggaagaga agagccgaca ggagctggag aagctgaaac ggaagctgga gggtgatgcc   3300

agcgacttcc acgagcagat cgctgacctc caggcgcaga tcgcagagct caagatgcag   3360

ctggccaaga aggaggagga gctgcaggcg gccctggcca ggcttgacga tgaaatcgct   3420

cagaagaaca atgccctgaa gaagatccgg gagctggagg gccacatctc agacctccag   3480

gaggacctgg actcagagcg ggccgccagg aacaaggctg aaaagcagaa gcgagacctc   3540

ggcgaggagc tggaggccct aaagacagag ctggaagaca cactggacag cacagccact   3600

cagcaggagc tcagggccaa gagggagcag gaggtgacgg tgctgaagaa ggccctggat   3660

gaagagacgc ggtcccatga ggctcaggtc caggagatga ggcagaaaca cgcacaggcg   3720

gtggaggagc tcacagagca gcttgagcag ttcaagaggg ccaaggcgaa cctagacaag   3780

aataagcaga cgctggagaa agagaacgca gacctggccg gggagctgcg ggtcctgggc   3840

caggccaagc aggaggtgga acataagaag aagaagctgg aggcgcaggt gcaggagctg   3900

cagtccaagt gcagcgatgg ggagcgggcc cgggcggagc tcaatgacaa agtccacaag   3960

ctgcagaatg aagttgagag cgtcacaggg atgcttaacg aggccgaggg gaaggccatt   4020

aagctggcca aggacgtggc gtccctcagt tcccagctcc aggacaccca ggagctgctt   4080

caagaagaaa cccggcagaa gctcaacgtg tctacgaagc tgcgccagct ggaggaggag   4140

cggaacagcc tgcaagacca gctggacgag gagatggagg ccaagcagaa cctggagcgc   4200

cacatctcca ctctcaacat ccagctctcc gactcgaaga agaagctgca ggactttgcc   4260

agcaccgtgg aagctctgga agaggggaag aagaggttcc agaaggagat cgagaacctc   4320

acccagcagt acgaggagaa ggcggccgct tatgataaac tggaaaagac caagaacagg   4380

cttcagcagg agctggacga cctggttgtt gatttggaca accagcggca actcgtgtcc   4440

aacctggaaa agaagcagag gaaatttgat cagttgttag ccgaggagaa aaacatctct   4500

tccaaatacg cggatgagag ggacagagct gaggcagaag ccagggagaa ggaaaccaag   4560

gccctgtccc tggctcgggc ccttgaagag gccttggaag ccaaagagga actcgagcgg   4620

accaacaaaa tgctcaaagc cgaaatggaa gacctggtca gctccaagga tgacgtgggc   4680

aagaacgtcc atgagctgga gaagtccaag cgggccctgg agacccagat ggaggagatg   4740

aagacgcagc tggaagagct ggaggacgag ctgcaagcca cggaggacgc caaactgcgg   4800

ctggaagtca acatgcaggc gctcaagggc cagttcgaaa gggatctcca agcccgggac   4860

gagcagaatg aggagaagag gaggcaactg cagagacagc ttcacgagta tgagacggaa   4920

ctggaagacg agcgaaagca acgtgccctg gcagctgcag caaagaagaa gctggaaggg   4980

gacctgaaag acctggagct tcaggccgac tctgccatca aggggaggga ggaagccatc   5040

aagcagctac gcaaactgca ggctcagatg aaggactttc aaagagagct ggaagatgcc   5100

cgtgcctcca gagatgagat ctttgccaca gccaaagaga atgagaagaa agccaagagc   5160

ttggaagcag acctcatgca gctacaagag gacctcgccg ccgctgagag ggctcgcaaa   5220

caagcggacc tcgagaagga ggaactggca gaggagctgg ccagtagcct gtcgggaagg   5280

aacgcactcc aggacgagaa gcgccgcctg gaggcccgga tcgcccagct ggaggaggag   5340

ctggaggagg agcagggcaa catggaggcc atgagcgacc gggtccgcaa agccacacag   5400

caggccgagc agctcagcaa cgagctggcc acagagcgca gcacggccca gaagaatgag   5460

agtgcccggc agcagctcga gcggcagaac aaggagctcc ggagcaagct ccacgagatg   5520

gagggggccg tcaagtccaa gttcaagtcc accatcgcgg cgctggaggc caagattgca   5580

cagctggagg agcaggtcga gcaggaggcc agagagaaac aggcggccac caagtcgctg   5640

aagcagaaag acaagaagct gaaggaaatc ttgctgcagg tggaggacga gcgcaagatg   5700

gccgagcagt acaaggagca ggcagagaaa ggcaatgcca gggtcaagca gctcaagagg   5760

cagctggagg aggcagagga ggagtcccag cgcatcaacg ccaaccgcag gaagctgcag   5820

cgggagctgg atgaggccac ggagagcaac gaggccatgg gccgcgaggt gaacgcactc   5880

aagagcaagc tcagagggcc ccccccacag gaaacttcgc agtgatgcac caggcgagga   5940

aacgagacct ctttcgttcc ttctagaagg tctggaggac gtagagttat tgaaaatgca   6000

gatggttctg aggaggaaac ggacactcga gacgcagact tcaatggaac caaggccagt   6060

gaataagcaa ctttctacag ttttgcacca cggcaagaaa accaaaaacc aaaacaaaca   6120

aacaaaaaaa acccaacaac aacccagaac aaagcaaaac ccagcagact gtacttagca   6180

ttgtctaaat ccattctcaa attccaaata tcacagacac ccctcacaca aggaatataa   6240

aaaccaccac cctccagcct gggcaacgta gtaaaacctc atctatacaa gaatttaaaa   6300

ataagctggg cgtggtggta cacacctgtg gtcccagcta ctagggaggc tgagccagga   6360

agaacgctcc agcccaggac ttcgaggctg caatgagcta taattgcatc attgcactcc   6420

agcctgggca acagagaccc tgtctcaacc accaccacca ccaccacccc tactacccct   6480

gtattcaagg taaaaattga agtttgtatg atgtaagaga tgagaaaaac ccaacaggaa   6540

acacagacac atcctccagt tctatcaatg gattgtgcag acactgagtt tttagaaaaa   6600

catatccacg gtaaccggtc cctggcaatt ctgtttacat gaaatgggga gaaagtcacc   6660

gaaatgggtg ccgccggccc ccactcccaa ttcattccct aacctgcaaa cctttccaac   6720

ttctcacgtc aggcctttga gaattctttc cccctctcct ggtttccaca cctcagacac   6780

gcacagttca ccaagtgcct tctgtagtca catgaattga aaaggagacg ctgctcccac   6840

ggaggggagc aggaatgctg cactgtttac accctgactg tgcttaaaaa cactttcact   6900

aataaatggt tataaatcac aat                                           6923


<210>  8870
<211>  1938
<212>  PRT
<213>  Homo sapiens

<400>  8870

Met Ala Gln Lys Gly Gln Leu Ser Asp Asp Glu Lys Phe Leu Phe Val 
1               5                   10                  15


Asp Lys Asn Phe Ile Asn Ser Pro Val Ala Gln Ala Asp Trp Ala Ala 
            20                  25                  30


Lys Arg Leu Val Trp Val Pro Ser Glu Lys Gln Gly Phe Glu Ala Ala 
        35                  40                  45


Ser Ile Lys Glu Glu Lys Gly Asp Glu Val Val Val Glu Leu Val Glu 
    50                  55                  60


Asn Gly Lys Lys Val Thr Val Gly Lys Asp Asp Ile Gln Lys Met Asn 
65                  70                  75                  80


Pro Pro Lys Phe Ser Lys Val Glu Asp Met Ala Glu Leu Thr Cys Leu 
                85                  90                  95


Asn Glu Ala Ser Val Leu His Asn Leu Arg Glu Arg Tyr Phe Ser Gly 
            100                 105                 110


Leu Ile Tyr Thr Tyr Ser Gly Leu Phe Cys Val Val Val Asn Pro Tyr 
        115                 120                 125


Lys His Leu Pro Ile Tyr Ser Glu Lys Ile Val Asp Met Tyr Lys Gly 
    130                 135                 140


Lys Lys Arg His Glu Met Pro Pro His Ile Tyr Ala Ile Ala Asp Thr 
145                 150                 155                 160


Ala Tyr Arg Ser Met Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys 
                165                 170                 175


Thr Gly Glu Ser Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile 
            180                 185                 190


Gln Tyr Leu Ala Val Val Ala Ser Ser His Lys Gly Lys Lys Asp Thr 
        195                 200                 205


Ser Ile Thr Gly Glu Leu Glu Lys Gln Leu Leu Gln Ala Asn Pro Ile 
    210                 215                 220


Leu Glu Ala Phe Gly Asn Ala Lys Thr Val Lys Asn Asp Asn Ser Ser 
225                 230                 235                 240


Arg Phe Gly Lys Phe Ile Arg Ile Asn Phe Asp Val Thr Gly Tyr Ile 
                245                 250                 255


Val Gly Ala Asn Ile Glu Thr Tyr Leu Leu Glu Lys Ser Arg Ala Ile 
            260                 265                 270


Arg Gln Ala Arg Asp Glu Arg Thr Phe His Ile Phe Tyr Tyr Met Ile 
        275                 280                 285


Ala Gly Ala Lys Glu Lys Met Arg Ser Asp Leu Leu Leu Glu Gly Phe 
    290                 295                 300


Asn Asn Tyr Thr Phe Leu Ser Asn Gly Phe Val Pro Ile Pro Ala Ala 
305                 310                 315                 320


Gln Asp Asp Glu Met Phe Gln Glu Thr Val Glu Ala Met Ala Ile Met 
                325                 330                 335


Gly Phe Ser Glu Glu Glu Gln Leu Ser Ile Leu Lys Val Val Ser Ser 
            340                 345                 350


Val Leu Gln Leu Gly Asn Ile Val Phe Lys Lys Glu Arg Asn Thr Asp 
        355                 360                 365


Gln Ala Ser Met Pro Asp Asn Thr Ala Ala Gln Lys Val Cys His Leu 
    370                 375                 380


Met Gly Ile Asn Val Thr Asp Phe Thr Arg Ser Ile Leu Thr Pro Arg 
385                 390                 395                 400


Ile Lys Val Gly Arg Asp Val Val Gln Lys Ala Gln Thr Lys Glu Gln 
                405                 410                 415


Ala Asp Phe Ala Val Glu Ala Leu Ala Lys Ala Thr Tyr Glu Arg Leu 
            420                 425                 430


Phe Arg Trp Ile Leu Thr Arg Val Asn Lys Ala Leu Asp Lys Thr His 
        435                 440                 445


Arg Gln Gly Ala Ser Phe Leu Gly Ile Leu Asp Ile Ala Gly Phe Glu 
    450                 455                 460


Ile Phe Glu Val Asn Ser Phe Glu Gln Leu Cys Ile Asn Tyr Thr Asn 
465                 470                 475                 480


Glu Lys Leu Gln Gln Leu Phe Asn His Thr Met Phe Ile Leu Glu Gln 
                485                 490                 495


Glu Glu Tyr Gln Arg Glu Gly Ile Glu Trp Asn Phe Ile Asp Phe Gly 
            500                 505                 510


Leu Asp Leu Gln Pro Cys Ile Glu Leu Ile Glu Arg Pro Asn Asn Pro 
        515                 520                 525


Pro Gly Val Leu Ala Leu Leu Asp Glu Glu Cys Trp Phe Pro Lys Ala 
    530                 535                 540


Thr Asp Lys Ser Phe Val Glu Lys Leu Cys Thr Glu Gln Gly Ser His 
545                 550                 555                 560


Pro Lys Phe Gln Lys Pro Lys Gln Leu Lys Asp Lys Thr Glu Phe Ser 
                565                 570                 575


Ile Ile His Tyr Ala Gly Lys Val Asp Tyr Asn Ala Ser Ala Trp Leu 
            580                 585                 590


Thr Lys Asn Met Asp Pro Leu Asn Asp Asn Val Thr Ser Leu Leu Asn 
        595                 600                 605


Ala Ser Ser Asp Lys Phe Val Ala Asp Leu Trp Lys Asp Val Asp Arg 
    610                 615                 620


Ile Val Gly Leu Asp Gln Met Ala Lys Met Thr Glu Ser Ser Leu Pro 
625                 630                 635                 640


Ser Ala Ser Lys Thr Lys Lys Gly Met Phe Arg Thr Val Gly Gln Leu 
                645                 650                 655


Tyr Lys Glu Gln Leu Gly Lys Leu Met Thr Thr Leu Arg Asn Thr Thr 
            660                 665                 670


Pro Asn Phe Val Arg Cys Ile Ile Pro Asn His Glu Lys Arg Ser Gly 
        675                 680                 685


Lys Leu Asp Ala Phe Leu Val Leu Glu Gln Leu Arg Cys Asn Gly Val 
    690                 695                 700


Leu Glu Gly Ile Arg Ile Cys Arg Gln Gly Phe Pro Asn Arg Ile Val 
705                 710                 715                 720


Phe Gln Glu Phe Arg Gln Arg Tyr Glu Ile Leu Ala Ala Asn Ala Ile 
                725                 730                 735


Pro Lys Gly Phe Met Asp Gly Lys Gln Ala Cys Ile Leu Met Ile Lys 
            740                 745                 750


Ala Leu Glu Leu Asp Pro Asn Leu Tyr Arg Ile Gly Gln Ser Lys Ile 
        755                 760                 765


Phe Phe Arg Thr Gly Val Leu Ala His Leu Glu Glu Glu Arg Asp Leu 
    770                 775                 780


Lys Ile Thr Asp Val Ile Met Ala Phe Gln Ala Met Cys Arg Gly Tyr 
785                 790                 795                 800


Leu Ala Arg Lys Ala Phe Ala Lys Arg Gln Gln Gln Leu Thr Ala Met 
                805                 810                 815


Lys Val Ile Gln Arg Asn Cys Ala Ala Tyr Leu Lys Leu Arg Asn Trp 
            820                 825                 830


Gln Trp Trp Arg Leu Phe Thr Lys Val Lys Pro Leu Leu Gln Val Thr 
        835                 840                 845


Arg Gln Glu Glu Glu Met Gln Ala Lys Glu Asp Glu Leu Gln Lys Thr 
    850                 855                 860


Lys Glu Arg Gln Gln Lys Ala Glu Asn Glu Leu Lys Glu Leu Glu Gln 
865                 870                 875                 880


Lys His Ser Gln Leu Thr Glu Glu Lys Asn Leu Leu Gln Glu Gln Leu 
                885                 890                 895


Gln Ala Glu Thr Glu Leu Tyr Ala Glu Ala Glu Glu Met Arg Val Arg 
            900                 905                 910


Leu Ala Ala Lys Lys Gln Glu Leu Glu Glu Ile Leu His Glu Met Glu 
        915                 920                 925


Ala Arg Leu Glu Glu Glu Glu Asp Arg Gly Gln Gln Leu Gln Ala Glu 
    930                 935                 940


Arg Lys Lys Met Ala Gln Gln Met Leu Asp Leu Glu Glu Gln Leu Glu 
945                 950                 955                 960


Glu Glu Glu Ala Ala Arg Gln Lys Leu Gln Leu Glu Lys Val Thr Ala 
                965                 970                 975


Glu Ala Lys Ile Lys Lys Leu Glu Asp Glu Ile Leu Val Met Asp Asp 
            980                 985                 990


Gln Asn Asn Lys Leu Ser Lys Glu Arg Lys Leu Leu Glu Glu Arg Ile 
        995                 1000                1005


Ser Asp Leu Thr Thr Asn Leu Ala Glu Glu Glu Glu Lys Ala Lys Asn 
    1010                1015                1020


Leu Thr Lys Leu Lys Asn Lys His Glu Ser Met Ile Ser Glu Leu Glu 
1025                1030                1035                1040


Val Arg Leu Lys Lys Glu Glu Lys Ser Arg Gln Glu Leu Glu Lys Leu 
                1045                1050                1055


Lys Arg Lys Leu Glu Gly Asp Ala Ser Asp Phe His Glu Gln Ile Ala 
            1060                1065                1070


Asp Leu Gln Ala Gln Ile Ala Glu Leu Lys Met Gln Leu Ala Lys Lys 
        1075                1080                1085


Glu Glu Glu Leu Gln Ala Ala Leu Ala Arg Leu Asp Asp Glu Ile Ala 
    1090                1095                1100


Gln Lys Asn Asn Ala Leu Lys Lys Ile Arg Glu Leu Glu Gly His Ile 
1105                1110                1115                1120


Ser Asp Leu Gln Glu Asp Leu Asp Ser Glu Arg Ala Ala Arg Asn Lys 
                1125                1130                1135


Ala Glu Lys Gln Lys Arg Asp Leu Gly Glu Glu Leu Glu Ala Leu Lys 
            1140                1145                1150


Thr Glu Leu Glu Asp Thr Leu Asp Ser Thr Ala Thr Gln Gln Glu Leu 
        1155                1160                1165


Arg Ala Lys Arg Glu Gln Glu Val Thr Val Leu Lys Lys Ala Leu Asp 
    1170                1175                1180


Glu Glu Thr Arg Ser His Glu Ala Gln Val Gln Glu Met Arg Gln Lys 
1185                1190                1195                1200


His Ala Gln Ala Val Glu Glu Leu Thr Glu Gln Leu Glu Gln Phe Lys 
                1205                1210                1215


Arg Ala Lys Ala Asn Leu Asp Lys Asn Lys Gln Thr Leu Glu Lys Glu 
            1220                1225                1230


Asn Ala Asp Leu Ala Gly Glu Leu Arg Val Leu Gly Gln Ala Lys Gln 
        1235                1240                1245


Glu Val Glu His Lys Lys Lys Lys Leu Glu Ala Gln Val Gln Glu Leu 
    1250                1255                1260


Gln Ser Lys Cys Ser Asp Gly Glu Arg Ala Arg Ala Glu Leu Asn Asp 
1265                1270                1275                1280


Lys Val His Lys Leu Gln Asn Glu Val Glu Ser Val Thr Gly Met Leu 
                1285                1290                1295


Asn Glu Ala Glu Gly Lys Ala Ile Lys Leu Ala Lys Asp Val Ala Ser 
            1300                1305                1310


Leu Ser Ser Gln Leu Gln Asp Thr Gln Glu Leu Leu Gln Glu Glu Thr 
        1315                1320                1325


Arg Gln Lys Leu Asn Val Ser Thr Lys Leu Arg Gln Leu Glu Glu Glu 
    1330                1335                1340


Arg Asn Ser Leu Gln Asp Gln Leu Asp Glu Glu Met Glu Ala Lys Gln 
1345                1350                1355                1360


Asn Leu Glu Arg His Ile Ser Thr Leu Asn Ile Gln Leu Ser Asp Ser 
                1365                1370                1375


Lys Lys Lys Leu Gln Asp Phe Ala Ser Thr Val Glu Ala Leu Glu Glu 
            1380                1385                1390


Gly Lys Lys Arg Phe Gln Lys Glu Ile Glu Asn Leu Thr Gln Gln Tyr 
        1395                1400                1405


Glu Glu Lys Ala Ala Ala Tyr Asp Lys Leu Glu Lys Thr Lys Asn Arg 
    1410                1415                1420


Leu Gln Gln Glu Leu Asp Asp Leu Val Val Asp Leu Asp Asn Gln Arg 
1425                1430                1435                1440


Gln Leu Val Ser Asn Leu Glu Lys Lys Gln Arg Lys Phe Asp Gln Leu 
                1445                1450                1455


Leu Ala Glu Glu Lys Asn Ile Ser Ser Lys Tyr Ala Asp Glu Arg Asp 
            1460                1465                1470


Arg Ala Glu Ala Glu Ala Arg Glu Lys Glu Thr Lys Ala Leu Ser Leu 
        1475                1480                1485


Ala Arg Ala Leu Glu Glu Ala Leu Glu Ala Lys Glu Glu Leu Glu Arg 
    1490                1495                1500


Thr Asn Lys Met Leu Lys Ala Glu Met Glu Asp Leu Val Ser Ser Lys 
1505                1510                1515                1520


Asp Asp Val Gly Lys Asn Val His Glu Leu Glu Lys Ser Lys Arg Ala 
                1525                1530                1535


Leu Glu Thr Gln Met Glu Glu Met Lys Thr Gln Leu Glu Glu Leu Glu 
            1540                1545                1550


Asp Glu Leu Gln Ala Thr Glu Asp Ala Lys Leu Arg Leu Glu Val Asn 
        1555                1560                1565


Met Gln Ala Leu Lys Gly Gln Phe Glu Arg Asp Leu Gln Ala Arg Asp 
    1570                1575                1580


Glu Gln Asn Glu Glu Lys Arg Arg Gln Leu Gln Arg Gln Leu His Glu 
1585                1590                1595                1600


Tyr Glu Thr Glu Leu Glu Asp Glu Arg Lys Gln Arg Ala Leu Ala Ala 
                1605                1610                1615


Ala Ala Lys Lys Lys Leu Glu Gly Asp Leu Lys Asp Leu Glu Leu Gln 
            1620                1625                1630


Ala Asp Ser Ala Ile Lys Gly Arg Glu Glu Ala Ile Lys Gln Leu Arg 
        1635                1640                1645


Lys Leu Gln Ala Gln Met Lys Asp Phe Gln Arg Glu Leu Glu Asp Ala 
    1650                1655                1660


Arg Ala Ser Arg Asp Glu Ile Phe Ala Thr Ala Lys Glu Asn Glu Lys 
1665                1670                1675                1680


Lys Ala Lys Ser Leu Glu Ala Asp Leu Met Gln Leu Gln Glu Asp Leu 
                1685                1690                1695


Ala Ala Ala Glu Arg Ala Arg Lys Gln Ala Asp Leu Glu Lys Glu Glu 
            1700                1705                1710


Leu Ala Glu Glu Leu Ala Ser Ser Leu Ser Gly Arg Asn Ala Leu Gln 
        1715                1720                1725


Asp Glu Lys Arg Arg Leu Glu Ala Arg Ile Ala Gln Leu Glu Glu Glu 
    1730                1735                1740


Leu Glu Glu Glu Gln Gly Asn Met Glu Ala Met Ser Asp Arg Val Arg 
1745                1750                1755                1760


Lys Ala Thr Gln Gln Ala Glu Gln Leu Ser Asn Glu Leu Ala Thr Glu 
                1765                1770                1775


Arg Ser Thr Ala Gln Lys Asn Glu Ser Ala Arg Gln Gln Leu Glu Arg 
            1780                1785                1790


Gln Asn Lys Glu Leu Arg Ser Lys Leu His Glu Met Glu Gly Ala Val 
        1795                1800                1805


Lys Ser Lys Phe Lys Ser Thr Ile Ala Ala Leu Glu Ala Lys Ile Ala 
    1810                1815                1820


Gln Leu Glu Glu Gln Val Glu Gln Glu Ala Arg Glu Lys Gln Ala Ala 
1825                1830                1835                1840


Thr Lys Ser Leu Lys Gln Lys Asp Lys Lys Leu Lys Glu Ile Leu Leu 
                1845                1850                1855


Gln Val Glu Asp Glu Arg Lys Met Ala Glu Gln Tyr Lys Glu Gln Ala 
            1860                1865                1870


Glu Lys Gly Asn Ala Arg Val Lys Gln Leu Lys Arg Gln Leu Glu Glu 
        1875                1880                1885


Ala Glu Glu Glu Ser Gln Arg Ile Asn Ala Asn Arg Arg Lys Leu Gln 
    1890                1895                1900


Arg Glu Leu Asp Glu Ala Thr Glu Ser Asn Glu Ala Met Gly Arg Glu 
1905                1910                1915                1920


Val Asn Ala Leu Lys Ser Lys Leu Arg Gly Pro Pro Pro Gln Glu Thr 
                1925                1930                1935


Ser Gln 



<210>  8871
<211>  6884
<212>  DNA
<213>  Homo sapiens

<400>  8871
agggagattt ggacgctccg gcctgggagg tgcgtcagat ccgagctcgc catccagttt     60

cctctccact agtcccccca gttggagatc tgggaccaac aaggcaccat ggcgcagaag    120

ggccaactca gtgacgatga gaagttcctc tttgtggaca aaaacttcat caacagccca    180

gtggcccagg ctgactgggc cgccaagaga ctcgtctggg tcccctcgga gaagcagggc    240

ttcgaggcag ccagcattaa ggaggagaag ggggatgagg tggttgtgga gctggtggag    300

aatggcaaga aggtcacggt tgggaaagat gacatccaga agatgaaccc acccaagttc    360

tccaaggtgg aggacatggc ggagctgacg tgcctcaacg aagcctccgt gctacacaac    420

ctgagggagc ggtacttctc agggctaata tatacgtact ctggcctctt ctgcgtggtg    480

gtcaacccct ataaacacct gcccatctac tcggagaaga tcgtcgacat gtacaagggc    540

aagaagaggc acgagatgcc gcctcacatc tacgccatcg cagacacggc ctaccggagc    600

atgcttcaag atcgggagga ccagtccatt ctatgcacag gcgagtctgg agccgggaaa    660

accgaaaaca ccaagaaggt cattcagtac ctggccgtgg tggcctcctc ccacaagggc    720

aagaaagaca caagtatcac gggagagctg gaaaagcagc ttctacaagc aaacccgatt    780

ctggaggctt tcggcaacgc caaaacagtg aagaacgaca actcctcacg attcggcaaa    840

ttcatccgca tcaacttcga cgtcacgggt tacatcgtgg gagccaacat tgagacctat    900

ctgctagaaa aatcacgggc aattcgccaa gccagagacg agaggacatt ccacatcttt    960

tactacatga ttgctggagc caaggagaag atgagaagtg acttgctttt ggagggcttc   1020

aacaactaca ccttcctctc caatggcttt gtgcccatcc cagcagccca ggatgatgag   1080

atgttccagg aaaccgtgga ggccatggca atcatgggtt tcagcgagga ggagcagcta   1140

tccatattga aggtggtatc atcggtcctg cagcttggaa atatcgtctt caagaaggaa   1200

agaaacacag accaggcgtc catgccagat aacacagctg ctcagaaagt ttgccacctc   1260

atgggaatta atgtgacaga tttcaccaga tccatcctca ctcctcgtat caaggttggg   1320

cgagatgtgg tacagaaagc tcagacaaaa gaacaggctg actttgctgt agaggctttg   1380

gccaaggcaa catatgagcg ccttttccgc tggatactca cccgcgtgaa caaagccctg   1440

gacaagaccc atcggcaagg ggcttccttc ctggggatcc tggatatagc tggatttgag   1500

atctttgagg tgaactcctt cgagcagctg tgcatcaact acaccaacga gaagctgcag   1560

cagctcttca accacaccat gttcatcctg gagcaggagg agtaccagcg cgagggcatc   1620

gagtggaact tcatcgactt tgggctggac ctacagccct gcatcgagct catcgagcga   1680

ccgaacaacc ctccaggtgt gctggccctg ctggacgagg aatgctggtt ccccaaagcc   1740

acggacaagt ctttcgtgga gaagctgtgc acggagcagg gcagccaccc caagttccag   1800

aagcccaagc agctcaagga caagactgag ttctccatca tccattatgc tgggaaggtg   1860

gactataatg cgagtgcctg gctgaccaag aatatggacc cgctgaatga caacgtgact   1920

tccctgctca atgcctcctc cgacaagttt gtggccgacc tgtggaagga cgtggaccgc   1980

atcgtgggcc tggaccagat ggccaagatg acggagagct cgctgcccag cgcctccaag   2040

accaagaagg gcatgttccg cacagtgggg cagctgtaca aggagcagct gggcaagctg   2100

atgaccacgc tacgcaacac cacgcccaac ttcgtgcgct gcatcatccc caaccacgag   2160

aagaggtccg gcaagctgga tgcgttcctg gtgctggagc agctgcggtg caatggggtg   2220

ctggaaggca ttcgcatctg ccggcagggc ttccccaacc ggatcgtctt ccaggagttc   2280

cgccaacgct acgagatcct ggcggcgaat gccatcccca aaggcttcat ggacgggaag   2340

caggcctgca ttctcatgat caaagccctg gaacttgacc ccaacttata caggataggg   2400

cagagcaaaa tcttcttccg aactggcgtc ctggcccacc tagaggagga gcgagatttg   2460

aagatcaccg atgtcatcat ggccttccag gcgatgtgtc gtggctactt ggccagaaag   2520

gcttttgcca agaggcagca gcagctgacc gccatgaagg tgattcagag gaactgcgcc   2580

gcctacctca agctgcggaa ctggcagtgg tggaggcttt tcaccaaagt gaagccactg   2640

ctgcaggtga cacggcagga ggaggagatg caggccaagg aggatgaact gcagaagacc   2700

aaggagcggc agcagaaggc agagaatgag cttaaggagc tggaacagaa gcactcgcag   2760

ctgaccgagg agaagaacct gctacaggaa cagctgcagg cagagacaga gctgtatgca   2820

gaggctgagg agatgcgggt gcggctggcg gccaagaagc aggagctgga ggagatactg   2880

catgagatgg aggcccgcct ggaggaggag gaagacaggg gccagcagct acaggctgaa   2940

aggaagaaga tggcccagca gatgctggac cttgaagaac agctggagga ggaggaagct   3000

gccaggcaga agctgcaact tgagaaggtc acggctgagg ccaagatcaa gaaactggag   3060

gatgagatcc tggtcatgga tgatcagaac aataaactat caaaagaacg aaaactcctt   3120

gaggagagga ttagtgactt aacgacaaat cttgcagaag aggaagaaaa ggccaagaat   3180

cttaccaagc tgaaaaacaa gcatgaatct atgatttcag aactggaagt gcggctaaag   3240

aaggaagaga agagccgaca ggagctggag aagctgaaac ggaagctgga gggtgatgcc   3300

agcgacttcc acgagcagat cgctgacctc caggcgcaga tcgcagagct caagatgcag   3360

ctggccaaga aggaggagga gctgcaggcg gccctggcca ggcttgacga tgaaatcgct   3420

cagaagaaca atgccctgaa gaagatccgg gagctggagg gccacatctc agacctccag   3480

gaggacctgg actcagagcg ggccgccagg aacaaggctg aaaagcagaa gcgagacctc   3540

ggcgaggagc tggaggccct aaagacagag ctggaagaca cactggacag cacagccact   3600

cagcaggagc tcagggccaa gagggagcag gaggtgacgg tgctgaagaa ggccctggat   3660

gaagagacgc ggtcccatga ggctcaggtc caggagatga ggcagaaaca cgcacaggcg   3720

gtggaggagc tcacagagca gcttgagcag ttcaagaggg ccaaggcgaa cctagacaag   3780

aataagcaga cgctggagaa agagaacgca gacctggccg gggagctgcg ggtcctgggc   3840

caggccaagc aggaggtgga acataagaag aagaagctgg aggcgcaggt gcaggagctg   3900

cagtccaagt gcagcgatgg ggagcgggcc cgggcggagc tcaatgacaa agtccacaag   3960

ctgcagaatg aagttgagag cgtcacaggg atgcttaacg aggccgaggg gaaggccatt   4020

aagctggcca aggacgtggc gtccctcagt tcccagctcc aggacaccca ggagctgctt   4080

caagaagaaa cccggcagaa gctcaacgtg tctacgaagc tgcgccagct ggaggaggag   4140

cggaacagcc tgcaagacca gctggacgag gagatggagg ccaagcagaa cctggagcgc   4200

cacatctcca ctctcaacat ccagctctcc gactcgaaga agaagctgca ggactttgcc   4260

agcaccgtgg aagctctgga agaggggaag aagaggttcc agaaggagat cgagaacctc   4320

acccagcagt acgaggagaa ggcggccgct tatgataaac tggaaaagac caagaacagg   4380

cttcagcagg agctggacga cctggttgtt gatttggaca accagcggca actcgtgtcc   4440

aacctggaaa agaagcagag gaaatttgat cagttgttag ccgaggagaa aaacatctct   4500

tccaaatacg cggatgagag ggacagagct gaggcagaag ccagggagaa ggaaaccaag   4560

gccctgtccc tggctcgggc ccttgaagag gccttggaag ccaaagagga actcgagcgg   4620

accaacaaaa tgctcaaagc cgaaatggaa gacctggtca gctccaagga tgacgtgggc   4680

aagaacgtcc atgagctgga gaagtccaag cgggccctgg agacccagat ggaggagatg   4740

aagacgcagc tggaagagct ggaggacgag ctgcaagcca cggaggacgc caaactgcgg   4800

ctggaagtca acatgcaggc gctcaagggc cagttcgaaa gggatctcca agcccgggac   4860

gagcagaatg aggagaagag gaggcaactg cagagacagc ttcacgagta tgagacggaa   4920

ctggaagacg agcgaaagca acgtgccctg gcagctgcag caaagaagaa gctggaaggg   4980

gacctgaaag acctggagct tcaggccgac tctgccatca aggggaggga ggaagccatc   5040

aagcagctac gcaaactgca ggctcagatg aaggactttc aaagagagct ggaagatgcc   5100

cgtgcctcca gagatgagat ctttgccaca gccaaagaga atgagaagaa agccaagagc   5160

ttggaagcag acctcatgca gctacaagag gacctcgccg ccgctgagag ggctcgcaaa   5220

caagcggacc tcgagaagga ggaactggca gaggagctgg ccagtagcct gtcgggaagg   5280

aacgcactcc aggacgagaa gcgccgcctg gaggcccgga tcgcccagct ggaggaggag   5340

ctggaggagg agcagggcaa catggaggcc atgagcgacc gggtccgcaa agccacacag   5400

caggccgagc agctcagcaa cgagctggcc acagagcgca gcacggccca gaagaatgag   5460

agtgcccggc agcagctcga gcggcagaac aaggagctcc ggagcaagct ccacgagatg   5520

gagggggccg tcaagtccaa gttcaagtcc accatcgcgg cgctggaggc caagattgca   5580

cagctggagg agcaggtcga gcaggaggcc agagagaaac aggcggccac caagtcgctg   5640

aagcagaaag acaagaagct gaaggaaatc ttgctgcagg tggaggacga gcgcaagatg   5700

gccgagcagt acaaggagca ggcagagaaa ggcaatgcca gggtcaagca gctcaagagg   5760

cagctggagg aggcagagga ggagtcccag cgcatcaacg ccaaccgcag gaagctgcag   5820

cgggagctgg atgaggccac ggagagcaac gaggccatgg gccgcgaggt gaacgcactc   5880

aagagcaagc tcaggcgagg aaacgagacc tctttcgttc cttctagaag gtctggagga   5940

cgtagagtta ttgaaaatgc agatggttct gaggaggaaa cggacactcg agacgcagac   6000

ttcaatggaa ccaaggccag tgaataagca actttctaca gttttgcacc acggcaagaa   6060

aaccaaaaac caaaacaaac aaacaaaaaa aacccaacaa caacccagaa caaagcaaaa   6120

cccagcagac tgtacttagc attgtctaaa tccattctca aattccaaat atcacagaca   6180

cccctcacac aaggaatata aaaaccacca ccctccagcc tgggcaacgt agtaaaacct   6240

catctataca agaatttaaa aataagctgg gcgtggtggt acacacctgt ggtcccagct   6300

actagggagg ctgagccagg aagaacgctc cagcccagga cttcgaggct gcaatgagct   6360

ataattgcat cattgcactc cagcctgggc aacagagacc ctgtctcaac caccaccacc   6420

accaccaccc ctactacccc tgtattcaag gtaaaaattg aagtttgtat gatgtaagag   6480

atgagaaaaa cccaacagga aacacagaca catcctccag ttctatcaat ggattgtgca   6540

gacactgagt ttttagaaaa acatatccac ggtaaccggt ccctggcaat tctgtttaca   6600

tgaaatgggg agaaagtcac cgaaatgggt gccgccggcc cccactccca attcattccc   6660

taacctgcaa acctttccaa cttctcacgt caggcctttg agaattcttt ccccctctcc   6720

tggtttccac acctcagaca cgcacagttc accaagtgcc ttctgtagtc acatgaattg   6780

aaaaggagac gctgctccca cggaggggag caggaatgct gcactgttta caccctgact   6840

gtgcttaaaa acactttcac taataaatgg ttataaatca caat                    6884


<210>  8872
<211>  1972
<212>  PRT
<213>  Homo sapiens

<400>  8872

Met Ala Gln Lys Gly Gln Leu Ser Asp Asp Glu Lys Phe Leu Phe Val 
1               5                   10                  15


Asp Lys Asn Phe Ile Asn Ser Pro Val Ala Gln Ala Asp Trp Ala Ala 
            20                  25                  30


Lys Arg Leu Val Trp Val Pro Ser Glu Lys Gln Gly Phe Glu Ala Ala 
        35                  40                  45


Ser Ile Lys Glu Glu Lys Gly Asp Glu Val Val Val Glu Leu Val Glu 
    50                  55                  60


Asn Gly Lys Lys Val Thr Val Gly Lys Asp Asp Ile Gln Lys Met Asn 
65                  70                  75                  80


Pro Pro Lys Phe Ser Lys Val Glu Asp Met Ala Glu Leu Thr Cys Leu 
                85                  90                  95


Asn Glu Ala Ser Val Leu His Asn Leu Arg Glu Arg Tyr Phe Ser Gly 
            100                 105                 110


Leu Ile Tyr Thr Tyr Ser Gly Leu Phe Cys Val Val Val Asn Pro Tyr 
        115                 120                 125


Lys His Leu Pro Ile Tyr Ser Glu Lys Ile Val Asp Met Tyr Lys Gly 
    130                 135                 140


Lys Lys Arg His Glu Met Pro Pro His Ile Tyr Ala Ile Ala Asp Thr 
145                 150                 155                 160


Ala Tyr Arg Ser Met Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys 
                165                 170                 175


Thr Gly Glu Ser Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile 
            180                 185                 190


Gln Tyr Leu Ala Val Val Ala Ser Ser His Lys Gly Lys Lys Asp Thr 
        195                 200                 205


Ser Ile Thr Gly Glu Leu Glu Lys Gln Leu Leu Gln Ala Asn Pro Ile 
    210                 215                 220


Leu Glu Ala Phe Gly Asn Ala Lys Thr Val Lys Asn Asp Asn Ser Ser 
225                 230                 235                 240


Arg Phe Gly Lys Phe Ile Arg Ile Asn Phe Asp Val Thr Gly Tyr Ile 
                245                 250                 255


Val Gly Ala Asn Ile Glu Thr Tyr Leu Leu Glu Lys Ser Arg Ala Ile 
            260                 265                 270


Arg Gln Ala Arg Asp Glu Arg Thr Phe His Ile Phe Tyr Tyr Met Ile 
        275                 280                 285


Ala Gly Ala Lys Glu Lys Met Arg Ser Asp Leu Leu Leu Glu Gly Phe 
    290                 295                 300


Asn Asn Tyr Thr Phe Leu Ser Asn Gly Phe Val Pro Ile Pro Ala Ala 
305                 310                 315                 320


Gln Asp Asp Glu Met Phe Gln Glu Thr Val Glu Ala Met Ala Ile Met 
                325                 330                 335


Gly Phe Ser Glu Glu Glu Gln Leu Ser Ile Leu Lys Val Val Ser Ser 
            340                 345                 350


Val Leu Gln Leu Gly Asn Ile Val Phe Lys Lys Glu Arg Asn Thr Asp 
        355                 360                 365


Gln Ala Ser Met Pro Asp Asn Thr Ala Ala Gln Lys Val Cys His Leu 
    370                 375                 380


Met Gly Ile Asn Val Thr Asp Phe Thr Arg Ser Ile Leu Thr Pro Arg 
385                 390                 395                 400


Ile Lys Val Gly Arg Asp Val Val Gln Lys Ala Gln Thr Lys Glu Gln 
                405                 410                 415


Ala Asp Phe Ala Val Glu Ala Leu Ala Lys Ala Thr Tyr Glu Arg Leu 
            420                 425                 430


Phe Arg Trp Ile Leu Thr Arg Val Asn Lys Ala Leu Asp Lys Thr His 
        435                 440                 445


Arg Gln Gly Ala Ser Phe Leu Gly Ile Leu Asp Ile Ala Gly Phe Glu 
    450                 455                 460


Ile Phe Glu Val Asn Ser Phe Glu Gln Leu Cys Ile Asn Tyr Thr Asn 
465                 470                 475                 480


Glu Lys Leu Gln Gln Leu Phe Asn His Thr Met Phe Ile Leu Glu Gln 
                485                 490                 495


Glu Glu Tyr Gln Arg Glu Gly Ile Glu Trp Asn Phe Ile Asp Phe Gly 
            500                 505                 510


Leu Asp Leu Gln Pro Cys Ile Glu Leu Ile Glu Arg Pro Asn Asn Pro 
        515                 520                 525


Pro Gly Val Leu Ala Leu Leu Asp Glu Glu Cys Trp Phe Pro Lys Ala 
    530                 535                 540


Thr Asp Lys Ser Phe Val Glu Lys Leu Cys Thr Glu Gln Gly Ser His 
545                 550                 555                 560


Pro Lys Phe Gln Lys Pro Lys Gln Leu Lys Asp Lys Thr Glu Phe Ser 
                565                 570                 575


Ile Ile His Tyr Ala Gly Lys Val Asp Tyr Asn Ala Ser Ala Trp Leu 
            580                 585                 590


Thr Lys Asn Met Asp Pro Leu Asn Asp Asn Val Thr Ser Leu Leu Asn 
        595                 600                 605


Ala Ser Ser Asp Lys Phe Val Ala Asp Leu Trp Lys Asp Val Asp Arg 
    610                 615                 620


Ile Val Gly Leu Asp Gln Met Ala Lys Met Thr Glu Ser Ser Leu Pro 
625                 630                 635                 640


Ser Ala Ser Lys Thr Lys Lys Gly Met Phe Arg Thr Val Gly Gln Leu 
                645                 650                 655


Tyr Lys Glu Gln Leu Gly Lys Leu Met Thr Thr Leu Arg Asn Thr Thr 
            660                 665                 670


Pro Asn Phe Val Arg Cys Ile Ile Pro Asn His Glu Lys Arg Ser Gly 
        675                 680                 685


Lys Leu Asp Ala Phe Leu Val Leu Glu Gln Leu Arg Cys Asn Gly Val 
    690                 695                 700


Leu Glu Gly Ile Arg Ile Cys Arg Gln Gly Phe Pro Asn Arg Ile Val 
705                 710                 715                 720


Phe Gln Glu Phe Arg Gln Arg Tyr Glu Ile Leu Ala Ala Asn Ala Ile 
                725                 730                 735


Pro Lys Gly Phe Met Asp Gly Lys Gln Ala Cys Ile Leu Met Ile Lys 
            740                 745                 750


Ala Leu Glu Leu Asp Pro Asn Leu Tyr Arg Ile Gly Gln Ser Lys Ile 
        755                 760                 765


Phe Phe Arg Thr Gly Val Leu Ala His Leu Glu Glu Glu Arg Asp Leu 
    770                 775                 780


Lys Ile Thr Asp Val Ile Met Ala Phe Gln Ala Met Cys Arg Gly Tyr 
785                 790                 795                 800


Leu Ala Arg Lys Ala Phe Ala Lys Arg Gln Gln Gln Leu Thr Ala Met 
                805                 810                 815


Lys Val Ile Gln Arg Asn Cys Ala Ala Tyr Leu Lys Leu Arg Asn Trp 
            820                 825                 830


Gln Trp Trp Arg Leu Phe Thr Lys Val Lys Pro Leu Leu Gln Val Thr 
        835                 840                 845


Arg Gln Glu Glu Glu Met Gln Ala Lys Glu Asp Glu Leu Gln Lys Thr 
    850                 855                 860


Lys Glu Arg Gln Gln Lys Ala Glu Asn Glu Leu Lys Glu Leu Glu Gln 
865                 870                 875                 880


Lys His Ser Gln Leu Thr Glu Glu Lys Asn Leu Leu Gln Glu Gln Leu 
                885                 890                 895


Gln Ala Glu Thr Glu Leu Tyr Ala Glu Ala Glu Glu Met Arg Val Arg 
            900                 905                 910


Leu Ala Ala Lys Lys Gln Glu Leu Glu Glu Ile Leu His Glu Met Glu 
        915                 920                 925


Ala Arg Leu Glu Glu Glu Glu Asp Arg Gly Gln Gln Leu Gln Ala Glu 
    930                 935                 940


Arg Lys Lys Met Ala Gln Gln Met Leu Asp Leu Glu Glu Gln Leu Glu 
945                 950                 955                 960


Glu Glu Glu Ala Ala Arg Gln Lys Leu Gln Leu Glu Lys Val Thr Ala 
                965                 970                 975


Glu Ala Lys Ile Lys Lys Leu Glu Asp Glu Ile Leu Val Met Asp Asp 
            980                 985                 990


Gln Asn Asn Lys Leu Ser Lys Glu Arg Lys Leu Leu Glu Glu Arg Ile 
        995                 1000                1005


Ser Asp Leu Thr Thr Asn Leu Ala Glu Glu Glu Glu Lys Ala Lys Asn 
    1010                1015                1020


Leu Thr Lys Leu Lys Asn Lys His Glu Ser Met Ile Ser Glu Leu Glu 
1025                1030                1035                1040


Val Arg Leu Lys Lys Glu Glu Lys Ser Arg Gln Glu Leu Glu Lys Leu 
                1045                1050                1055


Lys Arg Lys Leu Glu Gly Asp Ala Ser Asp Phe His Glu Gln Ile Ala 
            1060                1065                1070


Asp Leu Gln Ala Gln Ile Ala Glu Leu Lys Met Gln Leu Ala Lys Lys 
        1075                1080                1085


Glu Glu Glu Leu Gln Ala Ala Leu Ala Arg Leu Asp Asp Glu Ile Ala 
    1090                1095                1100


Gln Lys Asn Asn Ala Leu Lys Lys Ile Arg Glu Leu Glu Gly His Ile 
1105                1110                1115                1120


Ser Asp Leu Gln Glu Asp Leu Asp Ser Glu Arg Ala Ala Arg Asn Lys 
                1125                1130                1135


Ala Glu Lys Gln Lys Arg Asp Leu Gly Glu Glu Leu Glu Ala Leu Lys 
            1140                1145                1150


Thr Glu Leu Glu Asp Thr Leu Asp Ser Thr Ala Thr Gln Gln Glu Leu 
        1155                1160                1165


Arg Ala Lys Arg Glu Gln Glu Val Thr Val Leu Lys Lys Ala Leu Asp 
    1170                1175                1180


Glu Glu Thr Arg Ser His Glu Ala Gln Val Gln Glu Met Arg Gln Lys 
1185                1190                1195                1200


His Ala Gln Ala Val Glu Glu Leu Thr Glu Gln Leu Glu Gln Phe Lys 
                1205                1210                1215


Arg Ala Lys Ala Asn Leu Asp Lys Asn Lys Gln Thr Leu Glu Lys Glu 
            1220                1225                1230


Asn Ala Asp Leu Ala Gly Glu Leu Arg Val Leu Gly Gln Ala Lys Gln 
        1235                1240                1245


Glu Val Glu His Lys Lys Lys Lys Leu Glu Ala Gln Val Gln Glu Leu 
    1250                1255                1260


Gln Ser Lys Cys Ser Asp Gly Glu Arg Ala Arg Ala Glu Leu Asn Asp 
1265                1270                1275                1280


Lys Val His Lys Leu Gln Asn Glu Val Glu Ser Val Thr Gly Met Leu 
                1285                1290                1295


Asn Glu Ala Glu Gly Lys Ala Ile Lys Leu Ala Lys Asp Val Ala Ser 
            1300                1305                1310


Leu Ser Ser Gln Leu Gln Asp Thr Gln Glu Leu Leu Gln Glu Glu Thr 
        1315                1320                1325


Arg Gln Lys Leu Asn Val Ser Thr Lys Leu Arg Gln Leu Glu Glu Glu 
    1330                1335                1340


Arg Asn Ser Leu Gln Asp Gln Leu Asp Glu Glu Met Glu Ala Lys Gln 
1345                1350                1355                1360


Asn Leu Glu Arg His Ile Ser Thr Leu Asn Ile Gln Leu Ser Asp Ser 
                1365                1370                1375


Lys Lys Lys Leu Gln Asp Phe Ala Ser Thr Val Glu Ala Leu Glu Glu 
            1380                1385                1390


Gly Lys Lys Arg Phe Gln Lys Glu Ile Glu Asn Leu Thr Gln Gln Tyr 
        1395                1400                1405


Glu Glu Lys Ala Ala Ala Tyr Asp Lys Leu Glu Lys Thr Lys Asn Arg 
    1410                1415                1420


Leu Gln Gln Glu Leu Asp Asp Leu Val Val Asp Leu Asp Asn Gln Arg 
1425                1430                1435                1440


Gln Leu Val Ser Asn Leu Glu Lys Lys Gln Arg Lys Phe Asp Gln Leu 
                1445                1450                1455


Leu Ala Glu Glu Lys Asn Ile Ser Ser Lys Tyr Ala Asp Glu Arg Asp 
            1460                1465                1470


Arg Ala Glu Ala Glu Ala Arg Glu Lys Glu Thr Lys Ala Leu Ser Leu 
        1475                1480                1485


Ala Arg Ala Leu Glu Glu Ala Leu Glu Ala Lys Glu Glu Leu Glu Arg 
    1490                1495                1500


Thr Asn Lys Met Leu Lys Ala Glu Met Glu Asp Leu Val Ser Ser Lys 
1505                1510                1515                1520


Asp Asp Val Gly Lys Asn Val His Glu Leu Glu Lys Ser Lys Arg Ala 
                1525                1530                1535


Leu Glu Thr Gln Met Glu Glu Met Lys Thr Gln Leu Glu Glu Leu Glu 
            1540                1545                1550


Asp Glu Leu Gln Ala Thr Glu Asp Ala Lys Leu Arg Leu Glu Val Asn 
        1555                1560                1565


Met Gln Ala Leu Lys Gly Gln Phe Glu Arg Asp Leu Gln Ala Arg Asp 
    1570                1575                1580


Glu Gln Asn Glu Glu Lys Arg Arg Gln Leu Gln Arg Gln Leu His Glu 
1585                1590                1595                1600


Tyr Glu Thr Glu Leu Glu Asp Glu Arg Lys Gln Arg Ala Leu Ala Ala 
                1605                1610                1615


Ala Ala Lys Lys Lys Leu Glu Gly Asp Leu Lys Asp Leu Glu Leu Gln 
            1620                1625                1630


Ala Asp Ser Ala Ile Lys Gly Arg Glu Glu Ala Ile Lys Gln Leu Arg 
        1635                1640                1645


Lys Leu Gln Ala Gln Met Lys Asp Phe Gln Arg Glu Leu Glu Asp Ala 
    1650                1655                1660


Arg Ala Ser Arg Asp Glu Ile Phe Ala Thr Ala Lys Glu Asn Glu Lys 
1665                1670                1675                1680


Lys Ala Lys Ser Leu Glu Ala Asp Leu Met Gln Leu Gln Glu Asp Leu 
                1685                1690                1695


Ala Ala Ala Glu Arg Ala Arg Lys Gln Ala Asp Leu Glu Lys Glu Glu 
            1700                1705                1710


Leu Ala Glu Glu Leu Ala Ser Ser Leu Ser Gly Arg Asn Ala Leu Gln 
        1715                1720                1725


Asp Glu Lys Arg Arg Leu Glu Ala Arg Ile Ala Gln Leu Glu Glu Glu 
    1730                1735                1740


Leu Glu Glu Glu Gln Gly Asn Met Glu Ala Met Ser Asp Arg Val Arg 
1745                1750                1755                1760


Lys Ala Thr Gln Gln Ala Glu Gln Leu Ser Asn Glu Leu Ala Thr Glu 
                1765                1770                1775


Arg Ser Thr Ala Gln Lys Asn Glu Ser Ala Arg Gln Gln Leu Glu Arg 
            1780                1785                1790


Gln Asn Lys Glu Leu Arg Ser Lys Leu His Glu Met Glu Gly Ala Val 
        1795                1800                1805


Lys Ser Lys Phe Lys Ser Thr Ile Ala Ala Leu Glu Ala Lys Ile Ala 
    1810                1815                1820


Gln Leu Glu Glu Gln Val Glu Gln Glu Ala Arg Glu Lys Gln Ala Ala 
1825                1830                1835                1840


Thr Lys Ser Leu Lys Gln Lys Asp Lys Lys Leu Lys Glu Ile Leu Leu 
                1845                1850                1855


Gln Val Glu Asp Glu Arg Lys Met Ala Glu Gln Tyr Lys Glu Gln Ala 
            1860                1865                1870


Glu Lys Gly Asn Ala Arg Val Lys Gln Leu Lys Arg Gln Leu Glu Glu 
        1875                1880                1885


Ala Glu Glu Glu Ser Gln Arg Ile Asn Ala Asn Arg Arg Lys Leu Gln 
    1890                1895                1900


Arg Glu Leu Asp Glu Ala Thr Glu Ser Asn Glu Ala Met Gly Arg Glu 
1905                1910                1915                1920


Val Asn Ala Leu Lys Ser Lys Leu Arg Arg Gly Asn Glu Thr Ser Phe 
                1925                1930                1935


Val Pro Ser Arg Arg Ser Gly Gly Arg Arg Val Ile Glu Asn Ala Asp 
            1940                1945                1950


Gly Ser Glu Glu Glu Thr Asp Thr Arg Asp Ala Asp Phe Asn Gly Thr 
        1955                1960                1965


Lys Ala Ser Glu 
    1970


<210>  8873
<211>  6944
<212>  DNA
<213>  Homo sapiens

<400>  8873
agggagattt ggacgctccg gcctgggagg tgcgtcagat ccgagctcgc catccagttt     60

cctctccact agtcccccca gttggagatc tgggaccaac aaggcaccat ggcgcagaag    120

ggccaactca gtgacgatga gaagttcctc tttgtggaca aaaacttcat caacagccca    180

gtggcccagg ctgactgggc cgccaagaga ctcgtctggg tcccctcgga gaagcagggc    240

ttcgaggcag ccagcattaa ggaggagaag ggggatgagg tggttgtgga gctggtggag    300

aatggcaaga aggtcacggt tgggaaagat gacatccaga agatgaaccc acccaagttc    360

tccaaggtgg aggacatggc ggagctgacg tgcctcaacg aagcctccgt gctacacaac    420

ctgagggagc ggtacttctc agggctaata tatacgtact ctggcctctt ctgcgtggtg    480

gtcaacccct ataaacacct gcccatctac tcggagaaga tcgtcgacat gtacaagggc    540

aagaagaggc acgagatgcc gcctcacatc tacgccatcg cagacacggc ctaccggagc    600

atgcttcaag atcgggagga ccagtccatt ctatgcacag gcgagtctgg agccgggaaa    660

accgaaaaca ccaagaaggt cattcagtac ctggccgtgg tggcctcctc ccacaagggc    720

aagaaagaca caagtatcac gcaaggccca tcttttgcct acggagagct ggaaaagcag    780

cttctacaag caaacccgat tctggaggct ttcggcaacg ccaaaacagt gaagaacgac    840

aactcctcac gattcggcaa attcatccgc atcaacttcg acgtcacggg ttacatcgtg    900

ggagccaaca ttgagaccta tctgctagaa aaatcacggg caattcgcca agccagagac    960

gagaggacat tccacatctt ttactacatg attgctggag ccaaggagaa gatgagaagt   1020

gacttgcttt tggagggctt caacaactac accttcctct ccaatggctt tgtgcccatc   1080

ccagcagccc aggatgatga gatgttccag gaaaccgtgg aggccatggc aatcatgggt   1140

ttcagcgagg aggagcagct atccatattg aaggtggtat catcggtcct gcagcttgga   1200

aatatcgtct tcaagaagga aagaaacaca gaccaggcgt ccatgccaga taacacagct   1260

gctcagaaag tttgccacct catgggaatt aatgtgacag atttcaccag atccatcctc   1320

actcctcgta tcaaggttgg gcgagatgtg gtacagaaag ctcagacaaa agaacaggct   1380

gactttgctg tagaggcttt ggccaaggca acatatgagc gccttttccg ctggatactc   1440

acccgcgtga acaaagccct ggacaagacc catcggcaag gggcttcctt cctggggatc   1500

ctggatatag ctggatttga gatctttgag gtgaactcct tcgagcagct gtgcatcaac   1560

tacaccaacg agaagctgca gcagctcttc aaccacacca tgttcatcct ggagcaggag   1620

gagtaccagc gcgagggcat cgagtggaac ttcatcgact ttgggctgga cctacagccc   1680

tgcatcgagc tcatcgagcg accgaacaac cctccaggtg tgctggccct gctggacgag   1740

gaatgctggt tccccaaagc cacggacaag tctttcgtgg agaagctgtg cacggagcag   1800

ggcagccacc ccaagttcca gaagcccaag cagctcaagg acaagactga gttctccatc   1860

atccattatg ctgggaaggt ggactataat gcgagtgcct ggctgaccaa gaatatggac   1920

ccgctgaatg acaacgtgac ttccctgctc aatgcctcct ccgacaagtt tgtggccgac   1980

ctgtggaagg acgtggaccg catcgtgggc ctggaccaga tggccaagat gacggagagc   2040

tcgctgccca gcgcctccaa gaccaagaag ggcatgttcc gcacagtggg gcagctgtac   2100

aaggagcagc tgggcaagct gatgaccacg ctacgcaaca ccacgcccaa cttcgtgcgc   2160

tgcatcatcc ccaaccacga gaagaggtcc ggcaagctgg atgcgttcct ggtgctggag   2220

cagctgcggt gcaatggggt gctggaaggc attcgcatct gccggcaggg cttccccaac   2280

cggatcgtct tccaggagtt ccgccaacgc tacgagatcc tggcggcgaa tgccatcccc   2340

aaaggcttca tggacgggaa gcaggcctgc attctcatga tcaaagccct ggaacttgac   2400

cccaacttat acaggatagg gcagagcaaa atcttcttcc gaactggcgt cctggcccac   2460

ctagaggagg agcgagattt gaagatcacc gatgtcatca tggccttcca ggcgatgtgt   2520

cgtggctact tggccagaaa ggcttttgcc aagaggcagc agcagctgac cgccatgaag   2580

gtgattcaga ggaactgcgc cgcctacctc aagctgcgga actggcagtg gtggaggctt   2640

ttcaccaaag tgaagccact gctgcaggtg acacggcagg aggaggagat gcaggccaag   2700

gaggatgaac tgcagaagac caaggagcgg cagcagaagg cagagaatga gcttaaggag   2760

ctggaacaga agcactcgca gctgaccgag gagaagaacc tgctacagga acagctgcag   2820

gcagagacag agctgtatgc agaggctgag gagatgcggg tgcggctggc ggccaagaag   2880

caggagctgg aggagatact gcatgagatg gaggcccgcc tggaggagga ggaagacagg   2940

ggccagcagc tacaggctga aaggaagaag atggcccagc agatgctgga ccttgaagaa   3000

cagctggagg aggaggaagc tgccaggcag aagctgcaac ttgagaaggt cacggctgag   3060

gccaagatca agaaactgga ggatgagatc ctggtcatgg atgatcagaa caataaacta   3120

tcaaaagaac gaaaactcct tgaggagagg attagtgact taacgacaaa tcttgcagaa   3180

gaggaagaaa aggccaagaa tcttaccaag ctgaaaaaca agcatgaatc tatgatttca   3240

gaactggaag tgcggctaaa gaaggaagag aagagccgac aggagctgga gaagctgaaa   3300

cggaagctgg agggtgatgc cagcgacttc cacgagcaga tcgctgacct ccaggcgcag   3360

atcgcagagc tcaagatgca gctggccaag aaggaggagg agctgcaggc ggccctggcc   3420

aggcttgacg atgaaatcgc tcagaagaac aatgccctga agaagatccg ggagctggag   3480

ggccacatct cagacctcca ggaggacctg gactcagagc gggccgccag gaacaaggct   3540

gaaaagcaga agcgagacct cggcgaggag ctggaggccc taaagacaga gctggaagac   3600

acactggaca gcacagccac tcagcaggag ctcagggcca agagggagca ggaggtgacg   3660

gtgctgaaga aggccctgga tgaagagacg cggtcccatg aggctcaggt ccaggagatg   3720

aggcagaaac acgcacaggc ggtggaggag ctcacagagc agcttgagca gttcaagagg   3780

gccaaggcga acctagacaa gaataagcag acgctggaga aagagaacgc agacctggcc   3840

ggggagctgc gggtcctggg ccaggccaag caggaggtgg aacataagaa gaagaagctg   3900

gaggcgcagg tgcaggagct gcagtccaag tgcagcgatg gggagcgggc ccgggcggag   3960

ctcaatgaca aagtccacaa gctgcagaat gaagttgaga gcgtcacagg gatgcttaac   4020

gaggccgagg ggaaggccat taagctggcc aaggacgtgg cgtccctcag ttcccagctc   4080

caggacaccc aggagctgct tcaagaagaa acccggcaga agctcaacgt gtctacgaag   4140

ctgcgccagc tggaggagga gcggaacagc ctgcaagacc agctggacga ggagatggag   4200

gccaagcaga acctggagcg ccacatctcc actctcaaca tccagctctc cgactcgaag   4260

aagaagctgc aggactttgc cagcaccgtg gaagctctgg aagaggggaa gaagaggttc   4320

cagaaggaga tcgagaacct cacccagcag tacgaggaga aggcggccgc ttatgataaa   4380

ctggaaaaga ccaagaacag gcttcagcag gagctggacg acctggttgt tgatttggac   4440

aaccagcggc aactcgtgtc caacctggaa aagaagcaga ggaaatttga tcagttgtta   4500

gccgaggaga aaaacatctc ttccaaatac gcggatgaga gggacagagc tgaggcagaa   4560

gccagggaga aggaaaccaa ggccctgtcc ctggctcggg cccttgaaga ggccttggaa   4620

gccaaagagg aactcgagcg gaccaacaaa atgctcaaag ccgaaatgga agacctggtc   4680

agctccaagg atgacgtggg caagaacgtc catgagctgg agaagtccaa gcgggccctg   4740

gagacccaga tggaggagat gaagacgcag ctggaagagc tggaggacga gctgcaagcc   4800

acggaggacg ccaaactgcg gctggaagtc aacatgcagg cgctcaaggg ccagttcgaa   4860

agggatctcc aagcccggga cgagcagaat gaggagaaga ggaggcaact gcagagacag   4920

cttcacgagt atgagacgga actggaagac gagcgaaagc aacgtgccct ggcagctgca   4980

gcaaagaaga agctggaagg ggacctgaaa gacctggagc ttcaggccga ctctgccatc   5040

aaggggaggg aggaagccat caagcagcta cgcaaactgc aggctcagat gaaggacttt   5100

caaagagagc tggaagatgc ccgtgcctcc agagatgaga tctttgccac agccaaagag   5160

aatgagaaga aagccaagag cttggaagca gacctcatgc agctacaaga ggacctcgcc   5220

gccgctgaga gggctcgcaa acaagcggac ctcgagaagg aggaactggc agaggagctg   5280

gccagtagcc tgtcgggaag gaacgcactc caggacgaga agcgccgcct ggaggcccgg   5340

atcgcccagc tggaggagga gctggaggag gagcagggca acatggaggc catgagcgac   5400

cgggtccgca aagccacaca gcaggccgag cagctcagca acgagctggc cacagagcgc   5460

agcacggccc agaagaatga gagtgcccgg cagcagctcg agcggcagaa caaggagctc   5520

cggagcaagc tccacgagat ggagggggcc gtcaagtcca agttcaagtc caccatcgcg   5580

gcgctggagg ccaagattgc acagctggag gagcaggtcg agcaggaggc cagagagaaa   5640

caggcggcca ccaagtcgct gaagcagaaa gacaagaagc tgaaggaaat cttgctgcag   5700

gtggaggacg agcgcaagat ggccgagcag tacaaggagc aggcagagaa aggcaatgcc   5760

agggtcaagc agctcaagag gcagctggag gaggcagagg aggagtccca gcgcatcaac   5820

gccaaccgca ggaagctgca gcgggagctg gatgaggcca cggagagcaa cgaggccatg   5880

ggccgcgagg tgaacgcact caagagcaag ctcagagggc cccccccaca ggaaacttcg   5940

cagtgatgca ccaggcgagg aaacgagacc tctttcgttc cttctagaag gtctggagga   6000

cgtagagtta ttgaaaatgc agatggttct gaggaggaaa cggacactcg agacgcagac   6060

ttcaatggaa ccaaggccag tgaataagca actttctaca gttttgcacc acggcaagaa   6120

aaccaaaaac caaaacaaac aaacaaaaaa aacccaacaa caacccagaa caaagcaaaa   6180

cccagcagac tgtacttagc attgtctaaa tccattctca aattccaaat atcacagaca   6240

cccctcacac aaggaatata aaaaccacca ccctccagcc tgggcaacgt agtaaaacct   6300

catctataca agaatttaaa aataagctgg gcgtggtggt acacacctgt ggtcccagct   6360

actagggagg ctgagccagg aagaacgctc cagcccagga cttcgaggct gcaatgagct   6420

ataattgcat cattgcactc cagcctgggc aacagagacc ctgtctcaac caccaccacc   6480

accaccaccc ctactacccc tgtattcaag gtaaaaattg aagtttgtat gatgtaagag   6540

atgagaaaaa cccaacagga aacacagaca catcctccag ttctatcaat ggattgtgca   6600

gacactgagt ttttagaaaa acatatccac ggtaaccggt ccctggcaat tctgtttaca   6660

tgaaatgggg agaaagtcac cgaaatgggt gccgccggcc cccactccca attcattccc   6720

taacctgcaa acctttccaa cttctcacgt caggcctttg agaattcttt ccccctctcc   6780

tggtttccac acctcagaca cgcacagttc accaagtgcc ttctgtagtc acatgaattg   6840

aaaaggagac gctgctccca cggaggggag caggaatgct gcactgttta caccctgact   6900

gtgcttaaaa acactttcac taataaatgg ttataaatca caat                    6944


<210>  8874
<211>  1945
<212>  PRT
<213>  Homo sapiens

<400>  8874

Met Ala Gln Lys Gly Gln Leu Ser Asp Asp Glu Lys Phe Leu Phe Val 
1               5                   10                  15


Asp Lys Asn Phe Ile Asn Ser Pro Val Ala Gln Ala Asp Trp Ala Ala 
            20                  25                  30


Lys Arg Leu Val Trp Val Pro Ser Glu Lys Gln Gly Phe Glu Ala Ala 
        35                  40                  45


Ser Ile Lys Glu Glu Lys Gly Asp Glu Val Val Val Glu Leu Val Glu 
    50                  55                  60


Asn Gly Lys Lys Val Thr Val Gly Lys Asp Asp Ile Gln Lys Met Asn 
65                  70                  75                  80


Pro Pro Lys Phe Ser Lys Val Glu Asp Met Ala Glu Leu Thr Cys Leu 
                85                  90                  95


Asn Glu Ala Ser Val Leu His Asn Leu Arg Glu Arg Tyr Phe Ser Gly 
            100                 105                 110


Leu Ile Tyr Thr Tyr Ser Gly Leu Phe Cys Val Val Val Asn Pro Tyr 
        115                 120                 125


Lys His Leu Pro Ile Tyr Ser Glu Lys Ile Val Asp Met Tyr Lys Gly 
    130                 135                 140


Lys Lys Arg His Glu Met Pro Pro His Ile Tyr Ala Ile Ala Asp Thr 
145                 150                 155                 160


Ala Tyr Arg Ser Met Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys 
                165                 170                 175


Thr Gly Glu Ser Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile 
            180                 185                 190


Gln Tyr Leu Ala Val Val Ala Ser Ser His Lys Gly Lys Lys Asp Thr 
        195                 200                 205


Ser Ile Thr Gln Gly Pro Ser Phe Ala Tyr Gly Glu Leu Glu Lys Gln 
    210                 215                 220


Leu Leu Gln Ala Asn Pro Ile Leu Glu Ala Phe Gly Asn Ala Lys Thr 
225                 230                 235                 240


Val Lys Asn Asp Asn Ser Ser Arg Phe Gly Lys Phe Ile Arg Ile Asn 
                245                 250                 255


Phe Asp Val Thr Gly Tyr Ile Val Gly Ala Asn Ile Glu Thr Tyr Leu 
            260                 265                 270


Leu Glu Lys Ser Arg Ala Ile Arg Gln Ala Arg Asp Glu Arg Thr Phe 
        275                 280                 285


His Ile Phe Tyr Tyr Met Ile Ala Gly Ala Lys Glu Lys Met Arg Ser 
    290                 295                 300


Asp Leu Leu Leu Glu Gly Phe Asn Asn Tyr Thr Phe Leu Ser Asn Gly 
305                 310                 315                 320


Phe Val Pro Ile Pro Ala Ala Gln Asp Asp Glu Met Phe Gln Glu Thr 
                325                 330                 335


Val Glu Ala Met Ala Ile Met Gly Phe Ser Glu Glu Glu Gln Leu Ser 
            340                 345                 350


Ile Leu Lys Val Val Ser Ser Val Leu Gln Leu Gly Asn Ile Val Phe 
        355                 360                 365


Lys Lys Glu Arg Asn Thr Asp Gln Ala Ser Met Pro Asp Asn Thr Ala 
    370                 375                 380


Ala Gln Lys Val Cys His Leu Met Gly Ile Asn Val Thr Asp Phe Thr 
385                 390                 395                 400


Arg Ser Ile Leu Thr Pro Arg Ile Lys Val Gly Arg Asp Val Val Gln 
                405                 410                 415


Lys Ala Gln Thr Lys Glu Gln Ala Asp Phe Ala Val Glu Ala Leu Ala 
            420                 425                 430


Lys Ala Thr Tyr Glu Arg Leu Phe Arg Trp Ile Leu Thr Arg Val Asn 
        435                 440                 445


Lys Ala Leu Asp Lys Thr His Arg Gln Gly Ala Ser Phe Leu Gly Ile 
    450                 455                 460


Leu Asp Ile Ala Gly Phe Glu Ile Phe Glu Val Asn Ser Phe Glu Gln 
465                 470                 475                 480


Leu Cys Ile Asn Tyr Thr Asn Glu Lys Leu Gln Gln Leu Phe Asn His 
                485                 490                 495


Thr Met Phe Ile Leu Glu Gln Glu Glu Tyr Gln Arg Glu Gly Ile Glu 
            500                 505                 510


Trp Asn Phe Ile Asp Phe Gly Leu Asp Leu Gln Pro Cys Ile Glu Leu 
        515                 520                 525


Ile Glu Arg Pro Asn Asn Pro Pro Gly Val Leu Ala Leu Leu Asp Glu 
    530                 535                 540


Glu Cys Trp Phe Pro Lys Ala Thr Asp Lys Ser Phe Val Glu Lys Leu 
545                 550                 555                 560


Cys Thr Glu Gln Gly Ser His Pro Lys Phe Gln Lys Pro Lys Gln Leu 
                565                 570                 575


Lys Asp Lys Thr Glu Phe Ser Ile Ile His Tyr Ala Gly Lys Val Asp 
            580                 585                 590


Tyr Asn Ala Ser Ala Trp Leu Thr Lys Asn Met Asp Pro Leu Asn Asp 
        595                 600                 605


Asn Val Thr Ser Leu Leu Asn Ala Ser Ser Asp Lys Phe Val Ala Asp 
    610                 615                 620


Leu Trp Lys Asp Val Asp Arg Ile Val Gly Leu Asp Gln Met Ala Lys 
625                 630                 635                 640


Met Thr Glu Ser Ser Leu Pro Ser Ala Ser Lys Thr Lys Lys Gly Met 
                645                 650                 655


Phe Arg Thr Val Gly Gln Leu Tyr Lys Glu Gln Leu Gly Lys Leu Met 
            660                 665                 670


Thr Thr Leu Arg Asn Thr Thr Pro Asn Phe Val Arg Cys Ile Ile Pro 
        675                 680                 685


Asn His Glu Lys Arg Ser Gly Lys Leu Asp Ala Phe Leu Val Leu Glu 
    690                 695                 700


Gln Leu Arg Cys Asn Gly Val Leu Glu Gly Ile Arg Ile Cys Arg Gln 
705                 710                 715                 720


Gly Phe Pro Asn Arg Ile Val Phe Gln Glu Phe Arg Gln Arg Tyr Glu 
                725                 730                 735


Ile Leu Ala Ala Asn Ala Ile Pro Lys Gly Phe Met Asp Gly Lys Gln 
            740                 745                 750


Ala Cys Ile Leu Met Ile Lys Ala Leu Glu Leu Asp Pro Asn Leu Tyr 
        755                 760                 765


Arg Ile Gly Gln Ser Lys Ile Phe Phe Arg Thr Gly Val Leu Ala His 
    770                 775                 780


Leu Glu Glu Glu Arg Asp Leu Lys Ile Thr Asp Val Ile Met Ala Phe 
785                 790                 795                 800


Gln Ala Met Cys Arg Gly Tyr Leu Ala Arg Lys Ala Phe Ala Lys Arg 
                805                 810                 815


Gln Gln Gln Leu Thr Ala Met Lys Val Ile Gln Arg Asn Cys Ala Ala 
            820                 825                 830


Tyr Leu Lys Leu Arg Asn Trp Gln Trp Trp Arg Leu Phe Thr Lys Val 
        835                 840                 845


Lys Pro Leu Leu Gln Val Thr Arg Gln Glu Glu Glu Met Gln Ala Lys 
    850                 855                 860


Glu Asp Glu Leu Gln Lys Thr Lys Glu Arg Gln Gln Lys Ala Glu Asn 
865                 870                 875                 880


Glu Leu Lys Glu Leu Glu Gln Lys His Ser Gln Leu Thr Glu Glu Lys 
                885                 890                 895


Asn Leu Leu Gln Glu Gln Leu Gln Ala Glu Thr Glu Leu Tyr Ala Glu 
            900                 905                 910


Ala Glu Glu Met Arg Val Arg Leu Ala Ala Lys Lys Gln Glu Leu Glu 
        915                 920                 925


Glu Ile Leu His Glu Met Glu Ala Arg Leu Glu Glu Glu Glu Asp Arg 
    930                 935                 940


Gly Gln Gln Leu Gln Ala Glu Arg Lys Lys Met Ala Gln Gln Met Leu 
945                 950                 955                 960


Asp Leu Glu Glu Gln Leu Glu Glu Glu Glu Ala Ala Arg Gln Lys Leu 
                965                 970                 975


Gln Leu Glu Lys Val Thr Ala Glu Ala Lys Ile Lys Lys Leu Glu Asp 
            980                 985                 990


Glu Ile Leu Val Met Asp Asp Gln Asn Asn Lys Leu Ser Lys Glu Arg 
        995                 1000                1005


Lys Leu Leu Glu Glu Arg Ile Ser Asp Leu Thr Thr Asn Leu Ala Glu 
    1010                1015                1020


Glu Glu Glu Lys Ala Lys Asn Leu Thr Lys Leu Lys Asn Lys His Glu 
1025                1030                1035                1040


Ser Met Ile Ser Glu Leu Glu Val Arg Leu Lys Lys Glu Glu Lys Ser 
                1045                1050                1055


Arg Gln Glu Leu Glu Lys Leu Lys Arg Lys Leu Glu Gly Asp Ala Ser 
            1060                1065                1070


Asp Phe His Glu Gln Ile Ala Asp Leu Gln Ala Gln Ile Ala Glu Leu 
        1075                1080                1085


Lys Met Gln Leu Ala Lys Lys Glu Glu Glu Leu Gln Ala Ala Leu Ala 
    1090                1095                1100


Arg Leu Asp Asp Glu Ile Ala Gln Lys Asn Asn Ala Leu Lys Lys Ile 
1105                1110                1115                1120


Arg Glu Leu Glu Gly His Ile Ser Asp Leu Gln Glu Asp Leu Asp Ser 
                1125                1130                1135


Glu Arg Ala Ala Arg Asn Lys Ala Glu Lys Gln Lys Arg Asp Leu Gly 
            1140                1145                1150


Glu Glu Leu Glu Ala Leu Lys Thr Glu Leu Glu Asp Thr Leu Asp Ser 
        1155                1160                1165


Thr Ala Thr Gln Gln Glu Leu Arg Ala Lys Arg Glu Gln Glu Val Thr 
    1170                1175                1180


Val Leu Lys Lys Ala Leu Asp Glu Glu Thr Arg Ser His Glu Ala Gln 
1185                1190                1195                1200


Val Gln Glu Met Arg Gln Lys His Ala Gln Ala Val Glu Glu Leu Thr 
                1205                1210                1215


Glu Gln Leu Glu Gln Phe Lys Arg Ala Lys Ala Asn Leu Asp Lys Asn 
            1220                1225                1230


Lys Gln Thr Leu Glu Lys Glu Asn Ala Asp Leu Ala Gly Glu Leu Arg 
        1235                1240                1245


Val Leu Gly Gln Ala Lys Gln Glu Val Glu His Lys Lys Lys Lys Leu 
    1250                1255                1260


Glu Ala Gln Val Gln Glu Leu Gln Ser Lys Cys Ser Asp Gly Glu Arg 
1265                1270                1275                1280


Ala Arg Ala Glu Leu Asn Asp Lys Val His Lys Leu Gln Asn Glu Val 
                1285                1290                1295


Glu Ser Val Thr Gly Met Leu Asn Glu Ala Glu Gly Lys Ala Ile Lys 
            1300                1305                1310


Leu Ala Lys Asp Val Ala Ser Leu Ser Ser Gln Leu Gln Asp Thr Gln 
        1315                1320                1325


Glu Leu Leu Gln Glu Glu Thr Arg Gln Lys Leu Asn Val Ser Thr Lys 
    1330                1335                1340


Leu Arg Gln Leu Glu Glu Glu Arg Asn Ser Leu Gln Asp Gln Leu Asp 
1345                1350                1355                1360


Glu Glu Met Glu Ala Lys Gln Asn Leu Glu Arg His Ile Ser Thr Leu 
                1365                1370                1375


Asn Ile Gln Leu Ser Asp Ser Lys Lys Lys Leu Gln Asp Phe Ala Ser 
            1380                1385                1390


Thr Val Glu Ala Leu Glu Glu Gly Lys Lys Arg Phe Gln Lys Glu Ile 
        1395                1400                1405


Glu Asn Leu Thr Gln Gln Tyr Glu Glu Lys Ala Ala Ala Tyr Asp Lys 
    1410                1415                1420


Leu Glu Lys Thr Lys Asn Arg Leu Gln Gln Glu Leu Asp Asp Leu Val 
1425                1430                1435                1440


Val Asp Leu Asp Asn Gln Arg Gln Leu Val Ser Asn Leu Glu Lys Lys 
                1445                1450                1455


Gln Arg Lys Phe Asp Gln Leu Leu Ala Glu Glu Lys Asn Ile Ser Ser 
            1460                1465                1470


Lys Tyr Ala Asp Glu Arg Asp Arg Ala Glu Ala Glu Ala Arg Glu Lys 
        1475                1480                1485


Glu Thr Lys Ala Leu Ser Leu Ala Arg Ala Leu Glu Glu Ala Leu Glu 
    1490                1495                1500


Ala Lys Glu Glu Leu Glu Arg Thr Asn Lys Met Leu Lys Ala Glu Met 
1505                1510                1515                1520


Glu Asp Leu Val Ser Ser Lys Asp Asp Val Gly Lys Asn Val His Glu 
                1525                1530                1535


Leu Glu Lys Ser Lys Arg Ala Leu Glu Thr Gln Met Glu Glu Met Lys 
            1540                1545                1550


Thr Gln Leu Glu Glu Leu Glu Asp Glu Leu Gln Ala Thr Glu Asp Ala 
        1555                1560                1565


Lys Leu Arg Leu Glu Val Asn Met Gln Ala Leu Lys Gly Gln Phe Glu 
    1570                1575                1580


Arg Asp Leu Gln Ala Arg Asp Glu Gln Asn Glu Glu Lys Arg Arg Gln 
1585                1590                1595                1600


Leu Gln Arg Gln Leu His Glu Tyr Glu Thr Glu Leu Glu Asp Glu Arg 
                1605                1610                1615


Lys Gln Arg Ala Leu Ala Ala Ala Ala Lys Lys Lys Leu Glu Gly Asp 
            1620                1625                1630


Leu Lys Asp Leu Glu Leu Gln Ala Asp Ser Ala Ile Lys Gly Arg Glu 
        1635                1640                1645


Glu Ala Ile Lys Gln Leu Arg Lys Leu Gln Ala Gln Met Lys Asp Phe 
    1650                1655                1660


Gln Arg Glu Leu Glu Asp Ala Arg Ala Ser Arg Asp Glu Ile Phe Ala 
1665                1670                1675                1680


Thr Ala Lys Glu Asn Glu Lys Lys Ala Lys Ser Leu Glu Ala Asp Leu 
                1685                1690                1695


Met Gln Leu Gln Glu Asp Leu Ala Ala Ala Glu Arg Ala Arg Lys Gln 
            1700                1705                1710


Ala Asp Leu Glu Lys Glu Glu Leu Ala Glu Glu Leu Ala Ser Ser Leu 
        1715                1720                1725


Ser Gly Arg Asn Ala Leu Gln Asp Glu Lys Arg Arg Leu Glu Ala Arg 
    1730                1735                1740


Ile Ala Gln Leu Glu Glu Glu Leu Glu Glu Glu Gln Gly Asn Met Glu 
1745                1750                1755                1760


Ala Met Ser Asp Arg Val Arg Lys Ala Thr Gln Gln Ala Glu Gln Leu 
                1765                1770                1775


Ser Asn Glu Leu Ala Thr Glu Arg Ser Thr Ala Gln Lys Asn Glu Ser 
            1780                1785                1790


Ala Arg Gln Gln Leu Glu Arg Gln Asn Lys Glu Leu Arg Ser Lys Leu 
        1795                1800                1805


His Glu Met Glu Gly Ala Val Lys Ser Lys Phe Lys Ser Thr Ile Ala 
    1810                1815                1820


Ala Leu Glu Ala Lys Ile Ala Gln Leu Glu Glu Gln Val Glu Gln Glu 
1825                1830                1835                1840


Ala Arg Glu Lys Gln Ala Ala Thr Lys Ser Leu Lys Gln Lys Asp Lys 
                1845                1850                1855


Lys Leu Lys Glu Ile Leu Leu Gln Val Glu Asp Glu Arg Lys Met Ala 
            1860                1865                1870


Glu Gln Tyr Lys Glu Gln Ala Glu Lys Gly Asn Ala Arg Val Lys Gln 
        1875                1880                1885


Leu Lys Arg Gln Leu Glu Glu Ala Glu Glu Glu Ser Gln Arg Ile Asn 
    1890                1895                1900


Ala Asn Arg Arg Lys Leu Gln Arg Glu Leu Asp Glu Ala Thr Glu Ser 
1905                1910                1915                1920


Asn Glu Ala Met Gly Arg Glu Val Asn Ala Leu Lys Ser Lys Leu Arg 
                1925                1930                1935


Gly Pro Pro Pro Gln Glu Thr Ser Gln 
            1940                1945


<210>  8875
<211>  6905
<212>  DNA
<213>  Homo sapiens

<400>  8875
agggagattt ggacgctccg gcctgggagg tgcgtcagat ccgagctcgc catccagttt     60

cctctccact agtcccccca gttggagatc tgggaccaac aaggcaccat ggcgcagaag    120

ggccaactca gtgacgatga gaagttcctc tttgtggaca aaaacttcat caacagccca    180

gtggcccagg ctgactgggc cgccaagaga ctcgtctggg tcccctcgga gaagcagggc    240

ttcgaggcag ccagcattaa ggaggagaag ggggatgagg tggttgtgga gctggtggag    300

aatggcaaga aggtcacggt tgggaaagat gacatccaga agatgaaccc acccaagttc    360

tccaaggtgg aggacatggc ggagctgacg tgcctcaacg aagcctccgt gctacacaac    420

ctgagggagc ggtacttctc agggctaata tatacgtact ctggcctctt ctgcgtggtg    480

gtcaacccct ataaacacct gcccatctac tcggagaaga tcgtcgacat gtacaagggc    540

aagaagaggc acgagatgcc gcctcacatc tacgccatcg cagacacggc ctaccggagc    600

atgcttcaag atcgggagga ccagtccatt ctatgcacag gcgagtctgg agccgggaaa    660

accgaaaaca ccaagaaggt cattcagtac ctggccgtgg tggcctcctc ccacaagggc    720

aagaaagaca caagtatcac gcaaggccca tcttttgcct acggagagct ggaaaagcag    780

cttctacaag caaacccgat tctggaggct ttcggcaacg ccaaaacagt gaagaacgac    840

aactcctcac gattcggcaa attcatccgc atcaacttcg acgtcacggg ttacatcgtg    900

ggagccaaca ttgagaccta tctgctagaa aaatcacggg caattcgcca agccagagac    960

gagaggacat tccacatctt ttactacatg attgctggag ccaaggagaa gatgagaagt   1020

gacttgcttt tggagggctt caacaactac accttcctct ccaatggctt tgtgcccatc   1080

ccagcagccc aggatgatga gatgttccag gaaaccgtgg aggccatggc aatcatgggt   1140

ttcagcgagg aggagcagct atccatattg aaggtggtat catcggtcct gcagcttgga   1200

aatatcgtct tcaagaagga aagaaacaca gaccaggcgt ccatgccaga taacacagct   1260

gctcagaaag tttgccacct catgggaatt aatgtgacag atttcaccag atccatcctc   1320

actcctcgta tcaaggttgg gcgagatgtg gtacagaaag ctcagacaaa agaacaggct   1380

gactttgctg tagaggcttt ggccaaggca acatatgagc gccttttccg ctggatactc   1440

acccgcgtga acaaagccct ggacaagacc catcggcaag gggcttcctt cctggggatc   1500

ctggatatag ctggatttga gatctttgag gtgaactcct tcgagcagct gtgcatcaac   1560

tacaccaacg agaagctgca gcagctcttc aaccacacca tgttcatcct ggagcaggag   1620

gagtaccagc gcgagggcat cgagtggaac ttcatcgact ttgggctgga cctacagccc   1680

tgcatcgagc tcatcgagcg accgaacaac cctccaggtg tgctggccct gctggacgag   1740

gaatgctggt tccccaaagc cacggacaag tctttcgtgg agaagctgtg cacggagcag   1800

ggcagccacc ccaagttcca gaagcccaag cagctcaagg acaagactga gttctccatc   1860

atccattatg ctgggaaggt ggactataat gcgagtgcct ggctgaccaa gaatatggac   1920

ccgctgaatg acaacgtgac ttccctgctc aatgcctcct ccgacaagtt tgtggccgac   1980

ctgtggaagg acgtggaccg catcgtgggc ctggaccaga tggccaagat gacggagagc   2040

tcgctgccca gcgcctccaa gaccaagaag ggcatgttcc gcacagtggg gcagctgtac   2100

aaggagcagc tgggcaagct gatgaccacg ctacgcaaca ccacgcccaa cttcgtgcgc   2160

tgcatcatcc ccaaccacga gaagaggtcc ggcaagctgg atgcgttcct ggtgctggag   2220

cagctgcggt gcaatggggt gctggaaggc attcgcatct gccggcaggg cttccccaac   2280

cggatcgtct tccaggagtt ccgccaacgc tacgagatcc tggcggcgaa tgccatcccc   2340

aaaggcttca tggacgggaa gcaggcctgc attctcatga tcaaagccct ggaacttgac   2400

cccaacttat acaggatagg gcagagcaaa atcttcttcc gaactggcgt cctggcccac   2460

ctagaggagg agcgagattt gaagatcacc gatgtcatca tggccttcca ggcgatgtgt   2520

cgtggctact tggccagaaa ggcttttgcc aagaggcagc agcagctgac cgccatgaag   2580

gtgattcaga ggaactgcgc cgcctacctc aagctgcgga actggcagtg gtggaggctt   2640

ttcaccaaag tgaagccact gctgcaggtg acacggcagg aggaggagat gcaggccaag   2700

gaggatgaac tgcagaagac caaggagcgg cagcagaagg cagagaatga gcttaaggag   2760

ctggaacaga agcactcgca gctgaccgag gagaagaacc tgctacagga acagctgcag   2820

gcagagacag agctgtatgc agaggctgag gagatgcggg tgcggctggc ggccaagaag   2880

caggagctgg aggagatact gcatgagatg gaggcccgcc tggaggagga ggaagacagg   2940

ggccagcagc tacaggctga aaggaagaag atggcccagc agatgctgga ccttgaagaa   3000

cagctggagg aggaggaagc tgccaggcag aagctgcaac ttgagaaggt cacggctgag   3060

gccaagatca agaaactgga ggatgagatc ctggtcatgg atgatcagaa caataaacta   3120

tcaaaagaac gaaaactcct tgaggagagg attagtgact taacgacaaa tcttgcagaa   3180

gaggaagaaa aggccaagaa tcttaccaag ctgaaaaaca agcatgaatc tatgatttca   3240

gaactggaag tgcggctaaa gaaggaagag aagagccgac aggagctgga gaagctgaaa   3300

cggaagctgg agggtgatgc cagcgacttc cacgagcaga tcgctgacct ccaggcgcag   3360

atcgcagagc tcaagatgca gctggccaag aaggaggagg agctgcaggc ggccctggcc   3420

aggcttgacg atgaaatcgc tcagaagaac aatgccctga agaagatccg ggagctggag   3480

ggccacatct cagacctcca ggaggacctg gactcagagc gggccgccag gaacaaggct   3540

gaaaagcaga agcgagacct cggcgaggag ctggaggccc taaagacaga gctggaagac   3600

acactggaca gcacagccac tcagcaggag ctcagggcca agagggagca ggaggtgacg   3660

gtgctgaaga aggccctgga tgaagagacg cggtcccatg aggctcaggt ccaggagatg   3720

aggcagaaac acgcacaggc ggtggaggag ctcacagagc agcttgagca gttcaagagg   3780

gccaaggcga acctagacaa gaataagcag acgctggaga aagagaacgc agacctggcc   3840

ggggagctgc gggtcctggg ccaggccaag caggaggtgg aacataagaa gaagaagctg   3900

gaggcgcagg tgcaggagct gcagtccaag tgcagcgatg gggagcgggc ccgggcggag   3960

ctcaatgaca aagtccacaa gctgcagaat gaagttgaga gcgtcacagg gatgcttaac   4020

gaggccgagg ggaaggccat taagctggcc aaggacgtgg cgtccctcag ttcccagctc   4080

caggacaccc aggagctgct tcaagaagaa acccggcaga agctcaacgt gtctacgaag   4140

ctgcgccagc tggaggagga gcggaacagc ctgcaagacc agctggacga ggagatggag   4200

gccaagcaga acctggagcg ccacatctcc actctcaaca tccagctctc cgactcgaag   4260

aagaagctgc aggactttgc cagcaccgtg gaagctctgg aagaggggaa gaagaggttc   4320

cagaaggaga tcgagaacct cacccagcag tacgaggaga aggcggccgc ttatgataaa   4380

ctggaaaaga ccaagaacag gcttcagcag gagctggacg acctggttgt tgatttggac   4440

aaccagcggc aactcgtgtc caacctggaa aagaagcaga ggaaatttga tcagttgtta   4500

gccgaggaga aaaacatctc ttccaaatac gcggatgaga gggacagagc tgaggcagaa   4560

gccagggaga aggaaaccaa ggccctgtcc ctggctcggg cccttgaaga ggccttggaa   4620

gccaaagagg aactcgagcg gaccaacaaa atgctcaaag ccgaaatgga agacctggtc   4680

agctccaagg atgacgtggg caagaacgtc catgagctgg agaagtccaa gcgggccctg   4740

gagacccaga tggaggagat gaagacgcag ctggaagagc tggaggacga gctgcaagcc   4800

acggaggacg ccaaactgcg gctggaagtc aacatgcagg cgctcaaggg ccagttcgaa   4860

agggatctcc aagcccggga cgagcagaat gaggagaaga ggaggcaact gcagagacag   4920

cttcacgagt atgagacgga actggaagac gagcgaaagc aacgtgccct ggcagctgca   4980

gcaaagaaga agctggaagg ggacctgaaa gacctggagc ttcaggccga ctctgccatc   5040

aaggggaggg aggaagccat caagcagcta cgcaaactgc aggctcagat gaaggacttt   5100

caaagagagc tggaagatgc ccgtgcctcc agagatgaga tctttgccac agccaaagag   5160

aatgagaaga aagccaagag cttggaagca gacctcatgc agctacaaga ggacctcgcc   5220

gccgctgaga gggctcgcaa acaagcggac ctcgagaagg aggaactggc agaggagctg   5280

gccagtagcc tgtcgggaag gaacgcactc caggacgaga agcgccgcct ggaggcccgg   5340

atcgcccagc tggaggagga gctggaggag gagcagggca acatggaggc catgagcgac   5400

cgggtccgca aagccacaca gcaggccgag cagctcagca acgagctggc cacagagcgc   5460

agcacggccc agaagaatga gagtgcccgg cagcagctcg agcggcagaa caaggagctc   5520

cggagcaagc tccacgagat ggagggggcc gtcaagtcca agttcaagtc caccatcgcg   5580

gcgctggagg ccaagattgc acagctggag gagcaggtcg agcaggaggc cagagagaaa   5640

caggcggcca ccaagtcgct gaagcagaaa gacaagaagc tgaaggaaat cttgctgcag   5700

gtggaggacg agcgcaagat ggccgagcag tacaaggagc aggcagagaa aggcaatgcc   5760

agggtcaagc agctcaagag gcagctggag gaggcagagg aggagtccca gcgcatcaac   5820

gccaaccgca ggaagctgca gcgggagctg gatgaggcca cggagagcaa cgaggccatg   5880

ggccgcgagg tgaacgcact caagagcaag ctcaggcgag gaaacgagac ctctttcgtt   5940

ccttctagaa ggtctggagg acgtagagtt attgaaaatg cagatggttc tgaggaggaa   6000

acggacactc gagacgcaga cttcaatgga accaaggcca gtgaataagc aactttctac   6060

agttttgcac cacggcaaga aaaccaaaaa ccaaaacaaa caaacaaaaa aaacccaaca   6120

acaacccaga acaaagcaaa acccagcaga ctgtacttag cattgtctaa atccattctc   6180

aaattccaaa tatcacagac acccctcaca caaggaatat aaaaaccacc accctccagc   6240

ctgggcaacg tagtaaaacc tcatctatac aagaatttaa aaataagctg ggcgtggtgg   6300

tacacacctg tggtcccagc tactagggag gctgagccag gaagaacgct ccagcccagg   6360

acttcgaggc tgcaatgagc tataattgca tcattgcact ccagcctggg caacagagac   6420

cctgtctcaa ccaccaccac caccaccacc cctactaccc ctgtattcaa ggtaaaaatt   6480

gaagtttgta tgatgtaaga gatgagaaaa acccaacagg aaacacagac acatcctcca   6540

gttctatcaa tggattgtgc agacactgag tttttagaaa aacatatcca cggtaaccgg   6600

tccctggcaa ttctgtttac atgaaatggg gagaaagtca ccgaaatggg tgccgccggc   6660

ccccactccc aattcattcc ctaacctgca aacctttcca acttctcacg tcaggccttt   6720

gagaattctt tccccctctc ctggtttcca cacctcagac acgcacagtt caccaagtgc   6780

cttctgtagt cacatgaatt gaaaaggaga cgctgctccc acggagggga gcaggaatgc   6840

tgcactgttt acaccctgac tgtgcttaaa aacactttca ctaataaatg gttataaatc   6900

acaat                                                               6905


<210>  8876
<211>  1979
<212>  PRT
<213>  Homo sapiens

<400>  8876

Met Ala Gln Lys Gly Gln Leu Ser Asp Asp Glu Lys Phe Leu Phe Val 
1               5                   10                  15


Asp Lys Asn Phe Ile Asn Ser Pro Val Ala Gln Ala Asp Trp Ala Ala 
            20                  25                  30


Lys Arg Leu Val Trp Val Pro Ser Glu Lys Gln Gly Phe Glu Ala Ala 
        35                  40                  45


Ser Ile Lys Glu Glu Lys Gly Asp Glu Val Val Val Glu Leu Val Glu 
    50                  55                  60


Asn Gly Lys Lys Val Thr Val Gly Lys Asp Asp Ile Gln Lys Met Asn 
65                  70                  75                  80


Pro Pro Lys Phe Ser Lys Val Glu Asp Met Ala Glu Leu Thr Cys Leu 
                85                  90                  95


Asn Glu Ala Ser Val Leu His Asn Leu Arg Glu Arg Tyr Phe Ser Gly 
            100                 105                 110


Leu Ile Tyr Thr Tyr Ser Gly Leu Phe Cys Val Val Val Asn Pro Tyr 
        115                 120                 125


Lys His Leu Pro Ile Tyr Ser Glu Lys Ile Val Asp Met Tyr Lys Gly 
    130                 135                 140


Lys Lys Arg His Glu Met Pro Pro His Ile Tyr Ala Ile Ala Asp Thr 
145                 150                 155                 160


Ala Tyr Arg Ser Met Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys 
                165                 170                 175


Thr Gly Glu Ser Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile 
            180                 185                 190


Gln Tyr Leu Ala Val Val Ala Ser Ser His Lys Gly Lys Lys Asp Thr 
        195                 200                 205


Ser Ile Thr Gln Gly Pro Ser Phe Ala Tyr Gly Glu Leu Glu Lys Gln 
    210                 215                 220


Leu Leu Gln Ala Asn Pro Ile Leu Glu Ala Phe Gly Asn Ala Lys Thr 
225                 230                 235                 240


Val Lys Asn Asp Asn Ser Ser Arg Phe Gly Lys Phe Ile Arg Ile Asn 
                245                 250                 255


Phe Asp Val Thr Gly Tyr Ile Val Gly Ala Asn Ile Glu Thr Tyr Leu 
            260                 265                 270


Leu Glu Lys Ser Arg Ala Ile Arg Gln Ala Arg Asp Glu Arg Thr Phe 
        275                 280                 285


His Ile Phe Tyr Tyr Met Ile Ala Gly Ala Lys Glu Lys Met Arg Ser 
    290                 295                 300


Asp Leu Leu Leu Glu Gly Phe Asn Asn Tyr Thr Phe Leu Ser Asn Gly 
305                 310                 315                 320


Phe Val Pro Ile Pro Ala Ala Gln Asp Asp Glu Met Phe Gln Glu Thr 
                325                 330                 335


Val Glu Ala Met Ala Ile Met Gly Phe Ser Glu Glu Glu Gln Leu Ser 
            340                 345                 350


Ile Leu Lys Val Val Ser Ser Val Leu Gln Leu Gly Asn Ile Val Phe 
        355                 360                 365


Lys Lys Glu Arg Asn Thr Asp Gln Ala Ser Met Pro Asp Asn Thr Ala 
    370                 375                 380


Ala Gln Lys Val Cys His Leu Met Gly Ile Asn Val Thr Asp Phe Thr 
385                 390                 395                 400


Arg Ser Ile Leu Thr Pro Arg Ile Lys Val Gly Arg Asp Val Val Gln 
                405                 410                 415


Lys Ala Gln Thr Lys Glu Gln Ala Asp Phe Ala Val Glu Ala Leu Ala 
            420                 425                 430


Lys Ala Thr Tyr Glu Arg Leu Phe Arg Trp Ile Leu Thr Arg Val Asn 
        435                 440                 445


Lys Ala Leu Asp Lys Thr His Arg Gln Gly Ala Ser Phe Leu Gly Ile 
    450                 455                 460


Leu Asp Ile Ala Gly Phe Glu Ile Phe Glu Val Asn Ser Phe Glu Gln 
465                 470                 475                 480


Leu Cys Ile Asn Tyr Thr Asn Glu Lys Leu Gln Gln Leu Phe Asn His 
                485                 490                 495


Thr Met Phe Ile Leu Glu Gln Glu Glu Tyr Gln Arg Glu Gly Ile Glu 
            500                 505                 510


Trp Asn Phe Ile Asp Phe Gly Leu Asp Leu Gln Pro Cys Ile Glu Leu 
        515                 520                 525


Ile Glu Arg Pro Asn Asn Pro Pro Gly Val Leu Ala Leu Leu Asp Glu 
    530                 535                 540


Glu Cys Trp Phe Pro Lys Ala Thr Asp Lys Ser Phe Val Glu Lys Leu 
545                 550                 555                 560


Cys Thr Glu Gln Gly Ser His Pro Lys Phe Gln Lys Pro Lys Gln Leu 
                565                 570                 575


Lys Asp Lys Thr Glu Phe Ser Ile Ile His Tyr Ala Gly Lys Val Asp 
            580                 585                 590


Tyr Asn Ala Ser Ala Trp Leu Thr Lys Asn Met Asp Pro Leu Asn Asp 
        595                 600                 605


Asn Val Thr Ser Leu Leu Asn Ala Ser Ser Asp Lys Phe Val Ala Asp 
    610                 615                 620


Leu Trp Lys Asp Val Asp Arg Ile Val Gly Leu Asp Gln Met Ala Lys 
625                 630                 635                 640


Met Thr Glu Ser Ser Leu Pro Ser Ala Ser Lys Thr Lys Lys Gly Met 
                645                 650                 655


Phe Arg Thr Val Gly Gln Leu Tyr Lys Glu Gln Leu Gly Lys Leu Met 
            660                 665                 670


Thr Thr Leu Arg Asn Thr Thr Pro Asn Phe Val Arg Cys Ile Ile Pro 
        675                 680                 685


Asn His Glu Lys Arg Ser Gly Lys Leu Asp Ala Phe Leu Val Leu Glu 
    690                 695                 700


Gln Leu Arg Cys Asn Gly Val Leu Glu Gly Ile Arg Ile Cys Arg Gln 
705                 710                 715                 720


Gly Phe Pro Asn Arg Ile Val Phe Gln Glu Phe Arg Gln Arg Tyr Glu 
                725                 730                 735


Ile Leu Ala Ala Asn Ala Ile Pro Lys Gly Phe Met Asp Gly Lys Gln 
            740                 745                 750


Ala Cys Ile Leu Met Ile Lys Ala Leu Glu Leu Asp Pro Asn Leu Tyr 
        755                 760                 765


Arg Ile Gly Gln Ser Lys Ile Phe Phe Arg Thr Gly Val Leu Ala His 
    770                 775                 780


Leu Glu Glu Glu Arg Asp Leu Lys Ile Thr Asp Val Ile Met Ala Phe 
785                 790                 795                 800


Gln Ala Met Cys Arg Gly Tyr Leu Ala Arg Lys Ala Phe Ala Lys Arg 
                805                 810                 815


Gln Gln Gln Leu Thr Ala Met Lys Val Ile Gln Arg Asn Cys Ala Ala 
            820                 825                 830


Tyr Leu Lys Leu Arg Asn Trp Gln Trp Trp Arg Leu Phe Thr Lys Val 
        835                 840                 845


Lys Pro Leu Leu Gln Val Thr Arg Gln Glu Glu Glu Met Gln Ala Lys 
    850                 855                 860


Glu Asp Glu Leu Gln Lys Thr Lys Glu Arg Gln Gln Lys Ala Glu Asn 
865                 870                 875                 880


Glu Leu Lys Glu Leu Glu Gln Lys His Ser Gln Leu Thr Glu Glu Lys 
                885                 890                 895


Asn Leu Leu Gln Glu Gln Leu Gln Ala Glu Thr Glu Leu Tyr Ala Glu 
            900                 905                 910


Ala Glu Glu Met Arg Val Arg Leu Ala Ala Lys Lys Gln Glu Leu Glu 
        915                 920                 925


Glu Ile Leu His Glu Met Glu Ala Arg Leu Glu Glu Glu Glu Asp Arg 
    930                 935                 940


Gly Gln Gln Leu Gln Ala Glu Arg Lys Lys Met Ala Gln Gln Met Leu 
945                 950                 955                 960


Asp Leu Glu Glu Gln Leu Glu Glu Glu Glu Ala Ala Arg Gln Lys Leu 
                965                 970                 975


Gln Leu Glu Lys Val Thr Ala Glu Ala Lys Ile Lys Lys Leu Glu Asp 
            980                 985                 990


Glu Ile Leu Val Met Asp Asp Gln Asn Asn Lys Leu Ser Lys Glu Arg 
        995                 1000                1005


Lys Leu Leu Glu Glu Arg Ile Ser Asp Leu Thr Thr Asn Leu Ala Glu 
    1010                1015                1020


Glu Glu Glu Lys Ala Lys Asn Leu Thr Lys Leu Lys Asn Lys His Glu 
1025                1030                1035                1040


Ser Met Ile Ser Glu Leu Glu Val Arg Leu Lys Lys Glu Glu Lys Ser 
                1045                1050                1055


Arg Gln Glu Leu Glu Lys Leu Lys Arg Lys Leu Glu Gly Asp Ala Ser 
            1060                1065                1070


Asp Phe His Glu Gln Ile Ala Asp Leu Gln Ala Gln Ile Ala Glu Leu 
        1075                1080                1085


Lys Met Gln Leu Ala Lys Lys Glu Glu Glu Leu Gln Ala Ala Leu Ala 
    1090                1095                1100


Arg Leu Asp Asp Glu Ile Ala Gln Lys Asn Asn Ala Leu Lys Lys Ile 
1105                1110                1115                1120


Arg Glu Leu Glu Gly His Ile Ser Asp Leu Gln Glu Asp Leu Asp Ser 
                1125                1130                1135


Glu Arg Ala Ala Arg Asn Lys Ala Glu Lys Gln Lys Arg Asp Leu Gly 
            1140                1145                1150


Glu Glu Leu Glu Ala Leu Lys Thr Glu Leu Glu Asp Thr Leu Asp Ser 
        1155                1160                1165


Thr Ala Thr Gln Gln Glu Leu Arg Ala Lys Arg Glu Gln Glu Val Thr 
    1170                1175                1180


Val Leu Lys Lys Ala Leu Asp Glu Glu Thr Arg Ser His Glu Ala Gln 
1185                1190                1195                1200


Val Gln Glu Met Arg Gln Lys His Ala Gln Ala Val Glu Glu Leu Thr 
                1205                1210                1215


Glu Gln Leu Glu Gln Phe Lys Arg Ala Lys Ala Asn Leu Asp Lys Asn 
            1220                1225                1230


Lys Gln Thr Leu Glu Lys Glu Asn Ala Asp Leu Ala Gly Glu Leu Arg 
        1235                1240                1245


Val Leu Gly Gln Ala Lys Gln Glu Val Glu His Lys Lys Lys Lys Leu 
    1250                1255                1260


Glu Ala Gln Val Gln Glu Leu Gln Ser Lys Cys Ser Asp Gly Glu Arg 
1265                1270                1275                1280


Ala Arg Ala Glu Leu Asn Asp Lys Val His Lys Leu Gln Asn Glu Val 
                1285                1290                1295


Glu Ser Val Thr Gly Met Leu Asn Glu Ala Glu Gly Lys Ala Ile Lys 
            1300                1305                1310


Leu Ala Lys Asp Val Ala Ser Leu Ser Ser Gln Leu Gln Asp Thr Gln 
        1315                1320                1325


Glu Leu Leu Gln Glu Glu Thr Arg Gln Lys Leu Asn Val Ser Thr Lys 
    1330                1335                1340


Leu Arg Gln Leu Glu Glu Glu Arg Asn Ser Leu Gln Asp Gln Leu Asp 
1345                1350                1355                1360


Glu Glu Met Glu Ala Lys Gln Asn Leu Glu Arg His Ile Ser Thr Leu 
                1365                1370                1375


Asn Ile Gln Leu Ser Asp Ser Lys Lys Lys Leu Gln Asp Phe Ala Ser 
            1380                1385                1390


Thr Val Glu Ala Leu Glu Glu Gly Lys Lys Arg Phe Gln Lys Glu Ile 
        1395                1400                1405


Glu Asn Leu Thr Gln Gln Tyr Glu Glu Lys Ala Ala Ala Tyr Asp Lys 
    1410                1415                1420


Leu Glu Lys Thr Lys Asn Arg Leu Gln Gln Glu Leu Asp Asp Leu Val 
1425                1430                1435                1440


Val Asp Leu Asp Asn Gln Arg Gln Leu Val Ser Asn Leu Glu Lys Lys 
                1445                1450                1455


Gln Arg Lys Phe Asp Gln Leu Leu Ala Glu Glu Lys Asn Ile Ser Ser 
            1460                1465                1470


Lys Tyr Ala Asp Glu Arg Asp Arg Ala Glu Ala Glu Ala Arg Glu Lys 
        1475                1480                1485


Glu Thr Lys Ala Leu Ser Leu Ala Arg Ala Leu Glu Glu Ala Leu Glu 
    1490                1495                1500


Ala Lys Glu Glu Leu Glu Arg Thr Asn Lys Met Leu Lys Ala Glu Met 
1505                1510                1515                1520


Glu Asp Leu Val Ser Ser Lys Asp Asp Val Gly Lys Asn Val His Glu 
                1525                1530                1535


Leu Glu Lys Ser Lys Arg Ala Leu Glu Thr Gln Met Glu Glu Met Lys 
            1540                1545                1550


Thr Gln Leu Glu Glu Leu Glu Asp Glu Leu Gln Ala Thr Glu Asp Ala 
        1555                1560                1565


Lys Leu Arg Leu Glu Val Asn Met Gln Ala Leu Lys Gly Gln Phe Glu 
    1570                1575                1580


Arg Asp Leu Gln Ala Arg Asp Glu Gln Asn Glu Glu Lys Arg Arg Gln 
1585                1590                1595                1600


Leu Gln Arg Gln Leu His Glu Tyr Glu Thr Glu Leu Glu Asp Glu Arg 
                1605                1610                1615


Lys Gln Arg Ala Leu Ala Ala Ala Ala Lys Lys Lys Leu Glu Gly Asp 
            1620                1625                1630


Leu Lys Asp Leu Glu Leu Gln Ala Asp Ser Ala Ile Lys Gly Arg Glu 
        1635                1640                1645


Glu Ala Ile Lys Gln Leu Arg Lys Leu Gln Ala Gln Met Lys Asp Phe 
    1650                1655                1660


Gln Arg Glu Leu Glu Asp Ala Arg Ala Ser Arg Asp Glu Ile Phe Ala 
1665                1670                1675                1680


Thr Ala Lys Glu Asn Glu Lys Lys Ala Lys Ser Leu Glu Ala Asp Leu 
                1685                1690                1695


Met Gln Leu Gln Glu Asp Leu Ala Ala Ala Glu Arg Ala Arg Lys Gln 
            1700                1705                1710


Ala Asp Leu Glu Lys Glu Glu Leu Ala Glu Glu Leu Ala Ser Ser Leu 
        1715                1720                1725


Ser Gly Arg Asn Ala Leu Gln Asp Glu Lys Arg Arg Leu Glu Ala Arg 
    1730                1735                1740


Ile Ala Gln Leu Glu Glu Glu Leu Glu Glu Glu Gln Gly Asn Met Glu 
1745                1750                1755                1760


Ala Met Ser Asp Arg Val Arg Lys Ala Thr Gln Gln Ala Glu Gln Leu 
                1765                1770                1775


Ser Asn Glu Leu Ala Thr Glu Arg Ser Thr Ala Gln Lys Asn Glu Ser 
            1780                1785                1790


Ala Arg Gln Gln Leu Glu Arg Gln Asn Lys Glu Leu Arg Ser Lys Leu 
        1795                1800                1805


His Glu Met Glu Gly Ala Val Lys Ser Lys Phe Lys Ser Thr Ile Ala 
    1810                1815                1820


Ala Leu Glu Ala Lys Ile Ala Gln Leu Glu Glu Gln Val Glu Gln Glu 
1825                1830                1835                1840


Ala Arg Glu Lys Gln Ala Ala Thr Lys Ser Leu Lys Gln Lys Asp Lys 
                1845                1850                1855


Lys Leu Lys Glu Ile Leu Leu Gln Val Glu Asp Glu Arg Lys Met Ala 
            1860                1865                1870


Glu Gln Tyr Lys Glu Gln Ala Glu Lys Gly Asn Ala Arg Val Lys Gln 
        1875                1880                1885


Leu Lys Arg Gln Leu Glu Glu Ala Glu Glu Glu Ser Gln Arg Ile Asn 
    1890                1895                1900


Ala Asn Arg Arg Lys Leu Gln Arg Glu Leu Asp Glu Ala Thr Glu Ser 
1905                1910                1915                1920


Asn Glu Ala Met Gly Arg Glu Val Asn Ala Leu Lys Ser Lys Leu Arg 
                1925                1930                1935


Arg Gly Asn Glu Thr Ser Phe Val Pro Ser Arg Arg Ser Gly Gly Arg 
            1940                1945                1950


Arg Val Ile Glu Asn Ala Asp Gly Ser Glu Glu Glu Thr Asp Thr Arg 
        1955                1960                1965


Asp Ala Asp Phe Asn Gly Thr Lys Ala Ser Glu 
    1970                1975


<210>  8877
<211>  737
<212>  DNA
<213>  Homo sapiens

<400>  8877
caacccagaa caaagcaaaa cccagcagac tgtacttagc attgtctaaa tccattctca     60

aattccaaat atcacagaca cccctcacac aaggaatata aaaaccacca ccctccagcc    120

tgggcaacgt agtaaaacct catctataca agaatttaaa aataagctgg gcgtggtggt    180

acacacctgt ggtcccagct actagggagg ctgagccagg aagaacgctc cagcccagga    240

cttcgaggct gcaatgagct ataattgcat cattgcactc cagcctgggc aacagagacc    300

ctgtctcaac caccaccacc accaccaccc ctactacccc tgtattcaag gtaaaaattg    360

aagtttgtat gatgtaagag atgagaaaaa cccaacagga aacacagaca catcctccag    420

ttctatcaat ggattgtgca gacactgagt ttttagaaaa acatatccac ggtaaccggt    480

ccctggcaat tctgtttaca tgaaatgggg agaaagtcac cgaaatgggt gccgccggcc    540

cccactccca attcattccc taacctgcaa acctttccaa cttctcacgt caggcctttg    600

agaattcttt ccccctctcc tggtttccac acctcagaca cgcacagttc accaagtgcc    660

ttctgtagtc acatgaattg aaaaggagac gctgctccca cggaggggag caggaatgac    720

tttcactaat aaatggt                                                   737


<210>  8878
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  8878

Met Gly Arg Lys Ser Pro Lys Trp Val Pro Pro Ala Pro Thr Pro Asn 
1               5                   10                  15


Ser Phe Pro Asn Leu Gln Thr Phe Pro Thr Ser His Val Arg Pro Leu 
            20                  25                  30


Arg Ile Leu Ser Pro Ser Pro Gly Phe His Thr Ser Asp Thr His Ser 
        35                  40                  45


Ser Pro Ser Ala Phe Cys Ser His Met Asn 
    50                  55


<210>  8879
<211>  2297
<212>  DNA
<213>  Homo sapiens

<400>  8879
agaagtaggc ttcaggtctt ggtgatcaag ttgtggccac aatagctaga tattgaactt     60

gatactattt ttatcatatt actttcatcg taaccagttg atagaggtga tgctggttta    120

aaaatataga ggaggttgga cacgagttgc cgctggttgt ccaaatcaac aaccaggtcg    180

tccagctcct gctgaagcct gttcttggtc ttttccagtt tatcataagc ggccgccttc    240

tcctcgtact gctgggtgag gttctcgatc tccttctgga acctcttctt cccctcttcc    300

agagcttcca cggtgctggc aaagtcctgc agcttcttct tcgagtcgga gagctacaag    360

gacagcgtcc agggtagggt gagaggggga ccatgagtgg cccctgtccc tggccccaca    420

gactctgaga agcgaagacc atgtctcctc gttggagaaa cccaatagca ggggaagctg    480

gggggtcaag caccatcgca ccaacactcc accgcgatct gcctgcgggg gatctcagcg    540

cagagaagtt gagaggaccc atgaaggaag caaggacacg gggcaggcac ctggatgttg    600

agagtggaga tgtggcgctc caggttctgc ttggcctcca tctcctcgtc cagctggtct    660

tgcaggctgt tccgctcctc ctccagctgg cgcagcttcg tagacacgtt gagcttctgc    720

cgggtttctt cttgaagcag ctcctgcaaa agggatgcaa agaggtccca gggacctgcc    780

ccgaggaagg ccacccccca ggtcccctgg atgatgtggc aggacactca cctgggtgtc    840

ctggagctgg gaactgaggg acgccacgtc cttggccagc ttaatggcct tcccctcggc    900

ctcgttaagc atccctgtga cgctctcaac ttcattctaa gggtgccaag agactggtta    960

gtcaaagcct ctagaagggg atcctcgttg aaaggagccc tttttactca aaacacatgg   1020

gctagtactt gaggtgttca ctgattgaga aaatacccgt gaggtatggg actctgataa   1080

aaaaaaaaaa aaacacacac acacacaaaa aaaacagaat ctgtggcttg aagggaactc   1140

cgtcacctat gagttgggac cctggcccta gactctgtgg ttctaagaac ttatttgagc   1200

cccaatggta ttgactggga cctgatccca ctaaatggat cctagatccc tgccaaggtt   1260

ggtagagaca aagcagcagg tctgagagtc cagacgaggt gctctggctg gtccactctc   1320

taaggctgga gaagggagac caggatggta cttgaacgtc ccagggatgc tgtcccatcc   1380

cttccttcct cactcctact ctttgaccct gatggccaaa gccagagacg caggccctaa   1440

aggtaaaaac gtcctctctg tattctctgg cttttactcc ctagtgtctc tgcataagtc   1500

cctttgaggc tgttagccta cccctccatc tcttccattg acaaggagga tatgaatgat   1560

cttgacactg cttatatgag ggcggcaaaa gccctgctct caactgcatg tgagaaaaaa   1620

acatctcact taattcttcc ctcgcccctt ggtccctggc tgtggacatg ttaaacattt   1680

gtgaaaactt tggccacgtc cccatgagtg gcaaggcagg gtaaatggct atgccaagtg   1740

aaagaagacc aaagacaaaa agaccatgtc attcagcagc ttaaaacccc tcaacagctt   1800

cacattgccc agagtaagga tcaacataca tgtaataggt tctcaaaagc cctacatcat   1860

ctgggtacaa gctccccctc caaccccact ctgtactatc tccccctacc cccaacccca   1920

gctgggcact ccagctctac tggctgtatg tctctctcct aatttttcta cttaccacag   1980

ggcctttgca cacgctgttc cctctgcctg gtagacttat ccatgctcct tagggaagcc   2040

tttcgtggct cctcctcccc caggttaggc cccctggtta tttacacttg ggcatcatgt   2100

gccttccctt tgctgcatca tttgacattc atttgtgtga ttattcatgt ctttcccttc   2160

ccttcccttc cccttactcg gctggagtcc tactggggca gcgacagtgt ctcttcttcc   2220

ttgctgttgg atctcaggat taagcacagt gcctggcata cagcaggtgc tcaataaata   2280

cttatcaaat tggaaaa                                                  2297


<210>  8880
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  8880

Met Ser Pro Arg Trp Arg Asn Pro Ile Ala Gly Glu Ala Gly Gly Ser 
1               5                   10                  15


Ser Thr Ile Ala Pro Thr Leu His Arg Asp Leu Pro Ala Gly Asp Leu 
            20                  25                  30


Ser Ala Glu Lys Leu Arg Gly Pro Met Lys Glu Ala Arg Thr Arg Gly 
        35                  40                  45


Arg His Leu Asp Val Glu Ser Gly Asp Val Ala Leu Gln Val Leu Leu 
    50                  55                  60


Gly Leu His Leu Leu Val Gln Leu Val Leu Gln Ala Val Pro Leu Leu 
65                  70                  75                  80


Leu Gln Leu Ala Gln Leu Arg Arg His Val Glu Leu Leu Pro Gly Phe 
                85                  90                  95


Phe Leu Lys Gln Leu Leu Gln Lys Gly Cys Lys Glu Val Pro Gly Thr 
            100                 105                 110


Cys Pro Glu Glu Gly His Pro Pro Gly Pro Leu Asp Asp Val Ala Gly 
        115                 120                 125


His Ser Pro Gly Cys Pro Gly Ala Gly Asn 
    130                 135


<210>  8881
<211>  256
<212>  DNA
<213>  Homo sapiens

<400>  8881
gagggaggaa gccatcaagc agctacgcaa actgcaggct cagatgaagg actttcaaag     60

agagctggaa gatgcccgtg cctccagaga tgagatcttt gccacagcca aagagaatga    120

gaagaaagcc aagagcttgg aagcagacct catgcagcta caagaggacc tcgccgccgc    180

tgagagggct cgcaaacaag cggacctcga gaaggaggaa ctggcagagg agctggccag    240

tagcctgtcg ggaagg                                                    256


<210>  8882
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  8882

Met Lys Asp Phe Gln Arg Glu Leu Glu Asp Ala Arg Ala Ser Arg Asp 
1               5                   10                  15


Glu Ile Phe Ala Thr Ala Lys Glu Asn Glu Lys Lys Ala Lys Ser Leu 
            20                  25                  30


Glu Ala Asp Leu Met Gln Leu Gln Glu Asp Leu Ala Ala Ala Glu Arg 
        35                  40                  45


Ala Arg Lys Gln Ala Asp Leu Glu Lys Glu Glu Leu Ala Glu Glu Leu 
    50                  55                  60


Ala Ser Ser Leu Ser Gly 
65                  70


<210>  8883
<211>  2347
<212>  DNA
<213>  Homo sapiens

<400>  8883
cgagttcctc tttggcttcc aaggcctctt caagggcccg agccagggac agggccttgg     60

tttccttctc cctggcttct gcctcagctc tgtccctctc atccgcgtat ttggaagaga    120

tgtttttctc ctcggctaac aactacaaca caagacccag aggtgacttc taggcatatc    180

cggggttgga cacgagttgc cgctggttgt ccaaatcaac aaccaggtcg tccagctcct    240

gctgaagcct gttcttggtc ttttccagtt tatcataagc ggccgccttc tcctcgtact    300

gctgggtgag gttctcgatc tccttctgga acctcttctt cccctcttcc agagcttcca    360

cggtgctggc aaagtcctgc agcttcttct tcgagtcgga gagctacaag gacagcgtcc    420

agggtagggt gagaggggga ccatgagtgg cccctgtccc tggccccaca gactctgaga    480

agcgaagacc atgtctcctc gttggagaaa cccaatagca ggggaagctg gggggtcaag    540

caccatcgca ccaacactcc accgcgatct gcctgcgggg gatctcagcg cagagaagtt    600

gagaggaccc atgaaggaag caaggacacg gggcaggcac ctggatgttg agagtggaga    660

tgtggcgctc caggttctgc ttggcctcca tctcctcgtc cagctggtct tgcaggctgt    720

tccgctcctc ctccagctgg cgcagcttcg tagacacgtt gagcttctgc cgggtttctt    780

cttgaagcag ctcctgcaaa agggatgcaa agaggtccca gggacctgcc ccgaggaagg    840

ccacccccca ggtcccctgg atgatgtggc aggacactca cctgggtgtc ctggagctgg    900

gaactgaggg acgccacgtc cttggccagc ttaatggcct tcccctcggc ctcgttaagc    960

atccctgtga cgctctcaac ttcattctaa gggtgccaag agactggtta gtcaaagcct   1020

ctagaagggg atcctcgttg aaaggagccc tttttactca aaacacatgg gctagtactt   1080

gaggtgttca ctgattgaga aaatacccgt gaggtatggg actctgataa aaaaaaaaaa   1140

aaacacacac acacacaaaa aaaacagaat ctgtggcttg aagggaactc cgtcacctat   1200

gagttgggac cctggcccta gactctgtgg ttctaagaac ttatttgagc cccaatggta   1260

ttgactggga cctgatccca ctaaatggat cctagatccc tgccaaggtt ggtagagaca   1320

aagcagcagg tctgagagtc cagacgaggt gctctggctg gtccactctc taaggctgga   1380

gaagggagac caggatggta cttgaacgtc ccagggatgc tgtcccatcc cttccttcct   1440

cactcctact ctttgaccct gatggccaaa gccagagacg caggccctaa aggtaaaaac   1500

gtcctctctg tattctctgg cttttactcc ctagtgtctc tgcataagtc cctttgaggc   1560

tgttagccta cccctccatc tcttccattg acaaggagga tatgaatgat cttgacactg   1620

cttatatgag ggcggcaaaa gccctgctct caactgcatg tgagaaaaaa acatctcact   1680

taattcttcc ctcgcccctt ggtccctggc tgtggacatg ttaaacattt gtgaaaactt   1740

tggccacgtc cccatgagtg gcaaggcagg gtaaatggct atgccaagtg aaagaagacc   1800

aaagacaaaa agaccatgtc attcagcagc ttaaaacccc tcaacagctt cacattgccc   1860

agagtaagga tcaacataca tgtaataggt tctcaaaagc cctacatcat ctgggtacaa   1920

gctccccctc caaccccact ctgtactatc tccccctacc cccaacccca gctgggcact   1980

ccagctctac tggctgtatg tctctctcct aatttttcta cttaccacag ggcctttgca   2040

cacgctgttc cctctgcctg gtagacttat ccatgctcct tagggaagcc tttcgtggct   2100

cctcctcccc caggttaggc cccctggtta tttacacttg ggcatcatgt gccttccctt   2160

tgctgcatca tttgacattc atttgtgtga ttattcatgt ctttcccttc ccttcccttc   2220

cccttactcg gctggagtcc tactggggca gcgacagtgt ctcttcttcc ttgctgttgg   2280

atctcaggat taagcacagt gcctggcata cagcaggtgc tcaataaata cttatcaaat   2340

tggaaaa                                                             2347


<210>  8884
<211>  138
<212>  PRT
<213>  Homo sapiens

<400>  8884

Met Ser Pro Arg Trp Arg Asn Pro Ile Ala Gly Glu Ala Gly Gly Ser 
1               5                   10                  15


Ser Thr Ile Ala Pro Thr Leu His Arg Asp Leu Pro Ala Gly Asp Leu 
            20                  25                  30


Ser Ala Glu Lys Leu Arg Gly Pro Met Lys Glu Ala Arg Thr Arg Gly 
        35                  40                  45


Arg His Leu Asp Val Glu Ser Gly Asp Val Ala Leu Gln Val Leu Leu 
    50                  55                  60


Gly Leu His Leu Leu Val Gln Leu Val Leu Gln Ala Val Pro Leu Leu 
65                  70                  75                  80


Leu Gln Leu Ala Gln Leu Arg Arg His Val Glu Leu Leu Pro Gly Phe 
                85                  90                  95


Phe Leu Lys Gln Leu Leu Gln Lys Gly Cys Lys Glu Val Pro Gly Thr 
            100                 105                 110


Cys Pro Glu Glu Gly His Pro Pro Gly Pro Leu Asp Asp Val Ala Gly 
        115                 120                 125


His Ser Pro Gly Cys Pro Gly Ala Gly Asn 
    130                 135


<210>  8885
<211>  1112
<212>  DNA
<213>  Homo sapiens

<400>  8885
caggcctctt tgggaagacg cagttattaa gaccaccagc agacggcatg tccattactg     60

acccgcacaa agcaggtaga ggtgcaaacc tctgcccatc tcaggtgcag ggaaacagag    120

gcctttgcct ctaacaactt gaattctgat gtagagacct ggttccatct gcttgtgggg    180

gaaacgttta acatcagctc ctacctgggc tccccaggcc ctcgtgcggt ttggccccag    240

ttctggggtc ttaggctggg ctaaggtttc tgggagccca tgtcccctag ggtccccgct    300

tcactgcttt gttaccacca agagactccc tgtccccatc tgaggtctgg cagctcttag    360

tcatgtcttg gagggaggac gggcatccag ggctgaccgg tcaacgtcca gcacctccca    420

gggactatgg gaagactgag tggtgggtct cgtcctctcg ggatacttgc gcttcttctt    480

actggtgatt gtgtgccccc tgttgtgtgc cttcctggac ctctctgagg gaggaaaggg    540

cagggcctga aacgttctcc cggccacagc ctccctgtta tccctcccct ctgcttcctt    600

cgccaggcca aggcgaacct agacaagaat aagcagacgc tggagaaaga gaacgcagac    660

ctggccgggg agctgcgggt cctgggccag gccaagcagg aggtggaaca taagaagaag    720

aagctggagg cgcaggtgca ggagctgcag tccaagtgca gcgatgggga gcgggcccgg    780

gcggagctca atgacaaagt ccacaagctg caggtgagga ggtggcgcgg tggtgtggtg    840

ggcagtgctg ggtggtgccc agttctgtgg ggaggagcct cttcccggct cgctgaggtc    900

tctcttgctg caaggcaagt cctttcctct agttgcgttc ctggaggaga ggcgatgatc    960

tccctgttca attaaatatt aaaaaaacct tctggccagg cacggtggct catgcctgta   1020

atcccagcac tttgggagac agaggtgggt ggatcacctg aggtcagggg tttgagacca   1080

gtctggccaa catggtgaaa agtctctact aa                                 1112


<210>  8886
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8886

Met Ser Trp Arg Glu Asp Gly His Pro Gly Leu Thr Gly Gln Arg Pro 
1               5                   10                  15


Ala Pro Pro Arg Asp Tyr Gly Lys Thr Glu Trp Trp Val Ser Ser Ser 
            20                  25                  30


Arg Asp Thr Cys Ala Ser Ser Tyr Trp 
        35                  40


<210>  8887
<211>  798
<212>  DNA
<213>  Homo sapiens

<400>  8887
aatatttaat tgaacaggga gatcatcgcc tctcctccag gaacgcaact agaggaaagg     60

acttgccttg cagcaagaga gacctcagcg agccgggaag aggctcctcc ccacagaact    120

gggcaccacc cagcactgcc caccacacca ccgcgccacc tcctcacctg cagcttgtgg    180

actttgtcat tgagctccgc ccgggcccgc tccccatcgc tgcacttgga ctgcagctcc    240

tgcacctgcg cctccagctt cttcttctta tgttccacct cctgcttggc ctggcccagg    300

acccgcagct ccccggccag accctgacct gtagtaattt gaggctgctg atgtcactct    360

tatgtgtcat caccaaaaag catcaccaaa aagcattacc ctcttgaact gctcaagctg    420

ctctgtgagc tcctccaccg cctgtgcgtg tttctgcctc atctcctgga cctgagcctc    480

atgggaccgc gtctcttcat ccagggcctt cttcagcacc gtcacctcct gctccctctt    540

ggcccttggt gggaggaaca cagtgaatgg cagttgggtg gagacagagg gtcatctcag    600

tgccgtgcaa aagaatgaga gctcttccag gacccagagc tgcagtcctc atcaccaccc    660

ctctctagct gtgtgacctt gggtcattca cctaacatct ctggacctaa aatttcctca    720

gctgcaaaat gtggagcata tcacctgcct aggacatctg taatgactgg caaacaaata    780

cacaaagtaa tagaattg                                                  798


<210>  8888
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  8888

Met Phe His Leu Leu Leu Gly Leu Ala Gln Asp Pro Gln Leu Pro Gly 
1               5                   10                  15


Gln Thr Leu Thr Cys Ser Asn Leu Arg Leu Leu Met Ser Leu Leu Cys 
            20                  25                  30


Val Ile Thr Lys Lys His His Gln Lys Ala Leu Pro Ser 
        35                  40                  45


<210>  8889
<211>  851
<212>  DNA
<213>  Homo sapiens

<400>  8889
aatatttaat tgaacaggga gatcatcgcc tctcctccag gaacgcaact agaggaaagg     60

acttgccttg cagcaagaga gacctcagcg agccgggaag aggctcctcc ccacagaact    120

gggcaccacc cagcactgcc caccacacca ccgcgccacc tcctcacctg cagcttgtgg    180

actttgtcat tgagctccgc ccgggcccgc tccccatcgc tgcacttgga ctgcagctcc    240

tgcacctgcg cctccagctt cttcttctta tgttccacct cctgcttggc ctggcccagg    300

acccgcagct ccccggccag accctgacct gtagtaattt gaggctgctg atgtcactct    360

tatgtgtcat caccaaaaag catcaccaaa aagcattacc ctcttgaact gctcaagctg    420

ctctgtgagc tcctccaccg cctgtgcgtg tttctgcctc atctcctgga cctgagcctc    480

atgggaccgc gtctcttcat ccagggcctt cttcagcacc gtcacctcct gctccctctt    540

ggcccttggt gggaggaaca cagtgaatgg cagttgggtg gagacagagg gtcatctcag    600

tgccgtgcaa aagaatgaga gctcttccag gacccagagc tgcagtcctc atcaccaccc    660

ctctctagct gtgtgacctt gggtcattca cctaacatct ctggacctaa aatttcctca    720

gctgcaaaat gtggagcata tcacctgcct aggacatctg taatgactgg caaacaaata    780

cacaaagtaa tagaattgaa aggatgtctg tgaactgcaa aattttgctt aaatattaat    840

gttggctctt a                                                         851


<210>  8890
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  8890

Met Phe His Leu Leu Leu Gly Leu Ala Gln Asp Pro Gln Leu Pro Gly 
1               5                   10                  15


Gln Thr Leu Thr Cys Ser Asn Leu Arg Leu Leu Met Ser Leu Leu Cys 
            20                  25                  30


Val Ile Thr Lys Lys His His Gln Lys Ala Leu Pro Ser 
        35                  40                  45


<210>  8891
<211>  3915
<212>  DNA
<213>  Homo sapiens

<400>  8891
gttgcagatc agaaggagaa ttacagttct tatttgggat ctgcttttgt gtgaccttgg     60

ccgagtcagt taactcctcg gggctatggt ttcatcatct ataaaattga gggtttgaac    120

caggtccccc gatttaaagc tctcttgcca agacttttca accttacctg ccagaatccc    180

cattctagaa agggagcctt tttcagagag catggagacc ccaagtttat gtgaacaaaa    240

gtgattcctt tagtcgtctt cccaccaaca aagaaatgcc cgtggtgctc cttgtaaatt    300

tccaccagtc tcagctgtgg tgattccact tgtagctgag atttgtatgc ggatgaggct    360

tttgcttcat ctttctctgg gagctacaaa aaggaggatg tgtggacaaa tcaaaacaga    420

aacaaatagc agcttcctgc tttgtcctgt agaccaggta ccctgatgcc ttcctagcat    480

gcggaggaat gaggaggaag ccatgcccat ccttgtcccc tctagacact ttcccggctc    540

ctgtccagcc cagccctgat gcctggaaaa ataaggaagg gaaagcagga ggggaggaca    600

aggagaaaaa ctcccagaat ccagggcctg gaggcctcgg ggcccaactg cagccgccat    660

gttttagggc taggccaaga gcagctcgtt tgctttccca gcttaactta ccacattggc    720

cctttcctgc catgattaat cacgtgaccg cgtttgtgca aaggcatccc ggcagagggg    780

gccggtgggc tgtgtacagt ctcagcttcc tttaacccaa tgaatggagc tcaggcaacc    840

tgctttgaag ctttattccg cagtccgcta agaggattcc tggtgggttt tgtgcattcc    900

ttacttgtct gctgtagaag acttcagaaa accagtcctg agaaagaaaa aattgcaact    960

taaaaaaaat tgcactaaaa taattagaag gaggcttgta gtggtttaac ttgaagaagg   1020

ctgcttgtta aacatgaaca gcagcacgac tgccatgtac agtgggacag gtggtgcact   1080

gcacaactcc ggggggcacc attcatcatg atgtaaatga catcaccgac attgtgcaag   1140

gcagtggctt tgagtggcag tgatgttgca cagatgagca ggccctggtc ttgaaaaaag   1200

tgaccttcct agggagcaga tgtcctagct attagagagc tcagacagtt gcttctcttc   1260

tgaaatcctc ctgtaaatct gaacattagc atcagggtct aagaggaggt aggagatagg   1320

agagaacctg tgggttaagg gcagagtttt gtgacaacat ccatccaagg tagaactgtc   1380

aggacctagg ttgctttctc caataactag atgtgaatga attttaggga gagctggaaa   1440

agcagcttct acaagcaaac ccgattctgg aggctttcgg caacgccaaa acagtgaaga   1500

acgacaactc ctcacgattc ggcaaattca tccgcatcaa cttcgacgtc acgggttaca   1560

tcgtgggagc caacattgag acctatctgc tagaaaaatc acgggcaatt cgccaagcca   1620

gagacgagag gacattccac atcttttact acatgattgc tggagccaag gagaagatga   1680

gaagtgactt gcttttggag ggcttcaaca actacacctt cctctccaat ggctttgtgc   1740

ccatcccagc agcccaggat gatgagatgt tccaggaaac cgtggaggcc atggcaatca   1800

tgggtttcag cgaggaggag cagctatcca tattgaaggt ggtatcatcg gtcctgcagc   1860

ttggaaatat cgtcttcaag aaggaaagaa acacagacca ggcgtccatg ccagataaca   1920

cagctgctca gaaagtttgc cacctcatgg gaattaatgt gacagatttc accagatcca   1980

tcctcactcc tcgtatcaag gttgggcgag atgtggtaca gaaagctcag acaaaagaac   2040

aggctgactt tgctgtagag gctttggcca aggcaacata tgagcgcctt ttccgctgga   2100

tactcacccg cgtgaacaaa gccctggaca agacccatcg gcaaggggct tccttcctgg   2160

ggatcctgga tatagctgga tttgagatct ttgaggtgaa ctccttcgag cagctgtgca   2220

tcaactacac caacgagaag ctgcagcagc tcttcaacca caccatgttc atcctggagc   2280

aggaggagta ccagcgcgag ggcatcgagt ggaacttcat cgactttggg ctggacctac   2340

agccctgcat cgagctcatc gagcgaccga acaaccctcc aggtgtgctg gccctgctgg   2400

acgaggaatg ctggttcccc aaagccacgg acaagtcttt cgtggagaag ctgtgcacgg   2460

agcagggcag ccaccccaag ttccagaagc ccaagcagct caaggacaag actgagttct   2520

ccatcatcca ttatgctggg aaggtggact ataatgcgag tgcctggctg accaagaata   2580

tggacccgct gaatgacaac gtgacttccc tgctcaatgc ctcctccgac aagtttgtgg   2640

ccgacctgtg gaaggacgtg gaccgcatcg tgggcctgga ccagatggcc aagatgacgg   2700

agagctcgct gcccagcgcc tccaagacca agaagggcat gttccgcaca gtggggcagc   2760

tgtacaagga gcagctgggc aagctgatga ccacgctacg caacaccacg cccaacttcg   2820

tgcgctgcat catccccaac cacgagaaga gggtgaggcc cgccgcccag accctggggc   2880

tcccagaagc cagggctgtc ccaagcggtc acagcgtccc cagggcgccc tctgccccca   2940

cctaccccga ggaccccatt ttccatgtgg ggaaggctat ctgaatctca gacccattcc   3000

ccatccctgg aggaaaagga ggaagggagg atgcatccag agacttttca gttgtggagt   3060

tgctgtgcag gtcatccagc cactcattca ttcattatcc caggaagtat tcactgggct   3120

ctgccctgtc ctgggtgctg gggagcagtg ttagaaaaat tgtagccctt ccctgtgggt   3180

ttctcataat ctggtgcagg catcttcagc ttggggcgat tgtgtcctct atatggacat   3240

gctacagaca tttttggttg tcacaaccag gagggggctg ttagtcagca tctagtgggt   3300

aggggccagg gatgccctaa gcattgtaca atgcacagga tggtccctca acccccagca   3360

cagaatccct acaagatgcc agtagtgctg aggttatggg agacacgggg agaggtaaac   3420

atacagctga tgatggtgat ggaatgtggt cagttaggag aacaccaaag agccagggct   3480

cctcccacag cctcaggact cagagaaagc ttctggtgaa cttgaacgtt aagaatgtgt   3540

ggccatcaac ttggtgacat ggaaggcagg gtggggccta ggataagcag ggggcctagg   3600

ataagcagag ggcccaggct aagcaagagt gtggaggtga gaagtgaagg aactaggtaa   3660

gaaaatgcta gatagtgtcc aggcgtgttg ctcacgcctg taatcccagc tactcaggag   3720

gctgagaaac aaaaatctgt tgaacccagg aggcggaggt tgcagtgagc tgagattgca   3780

ccacagcatt ccagcctggg cagcagagcg agactccatc ttaaaaaaaa aaaaaaaaaa   3840

ggaaagaaaa tgctaaatag gtcatttcat gttgcaaatg tgtgatggca tgaggtagga   3900

atcagatggt gtgag                                                    3915


<210>  8892
<211>  443
<212>  PRT
<213>  Homo sapiens

<400>  8892

Met Ile Ala Gly Ala Lys Glu Lys Met Arg Ser Asp Leu Leu Leu Glu 
1               5                   10                  15


Gly Phe Asn Asn Tyr Thr Phe Leu Ser Asn Gly Phe Val Pro Ile Pro 
            20                  25                  30


Ala Ala Gln Asp Asp Glu Met Phe Gln Glu Thr Val Glu Ala Met Ala 
        35                  40                  45


Ile Met Gly Phe Ser Glu Glu Glu Gln Leu Ser Ile Leu Lys Val Val 
    50                  55                  60


Ser Ser Val Leu Gln Leu Gly Asn Ile Val Phe Lys Lys Glu Arg Asn 
65                  70                  75                  80


Thr Asp Gln Ala Ser Met Pro Asp Asn Thr Ala Ala Gln Lys Val Cys 
                85                  90                  95


His Leu Met Gly Ile Asn Val Thr Asp Phe Thr Arg Ser Ile Leu Thr 
            100                 105                 110


Pro Arg Ile Lys Val Gly Arg Asp Val Val Gln Lys Ala Gln Thr Lys 
        115                 120                 125


Glu Gln Ala Asp Phe Ala Val Glu Ala Leu Ala Lys Ala Thr Tyr Glu 
    130                 135                 140


Arg Leu Phe Arg Trp Ile Leu Thr Arg Val Asn Lys Ala Leu Asp Lys 
145                 150                 155                 160


Thr His Arg Gln Gly Ala Ser Phe Leu Gly Ile Leu Asp Ile Ala Gly 
                165                 170                 175


Phe Glu Ile Phe Glu Val Asn Ser Phe Glu Gln Leu Cys Ile Asn Tyr 
            180                 185                 190


Thr Asn Glu Lys Leu Gln Gln Leu Phe Asn His Thr Met Phe Ile Leu 
        195                 200                 205


Glu Gln Glu Glu Tyr Gln Arg Glu Gly Ile Glu Trp Asn Phe Ile Asp 
    210                 215                 220


Phe Gly Leu Asp Leu Gln Pro Cys Ile Glu Leu Ile Glu Arg Pro Asn 
225                 230                 235                 240


Asn Pro Pro Gly Val Leu Ala Leu Leu Asp Glu Glu Cys Trp Phe Pro 
                245                 250                 255


Lys Ala Thr Asp Lys Ser Phe Val Glu Lys Leu Cys Thr Glu Gln Gly 
            260                 265                 270


Ser His Pro Lys Phe Gln Lys Pro Lys Gln Leu Lys Asp Lys Thr Glu 
        275                 280                 285


Phe Ser Ile Ile His Tyr Ala Gly Lys Val Asp Tyr Asn Ala Ser Ala 
    290                 295                 300


Trp Leu Thr Lys Asn Met Asp Pro Leu Asn Asp Asn Val Thr Ser Leu 
305                 310                 315                 320


Leu Asn Ala Ser Ser Asp Lys Phe Val Ala Asp Leu Trp Lys Asp Val 
                325                 330                 335


Asp Arg Ile Val Gly Leu Asp Gln Met Ala Lys Met Thr Glu Ser Ser 
            340                 345                 350


Leu Pro Ser Ala Ser Lys Thr Lys Lys Gly Met Phe Arg Thr Val Gly 
        355                 360                 365


Gln Leu Tyr Lys Glu Gln Leu Gly Lys Leu Met Thr Thr Leu Arg Asn 
    370                 375                 380


Thr Thr Pro Asn Phe Val Arg Cys Ile Ile Pro Asn His Glu Lys Arg 
385                 390                 395                 400


Val Arg Pro Ala Ala Gln Thr Leu Gly Leu Pro Glu Ala Arg Ala Val 
                405                 410                 415


Pro Ser Gly His Ser Val Pro Arg Ala Pro Ser Ala Pro Thr Tyr Pro 
            420                 425                 430


Glu Asp Pro Ile Phe His Val Gly Lys Ala Ile 
        435                 440


<210>  8893
<211>  353
<212>  DNA
<213>  Homo sapiens

<400>  8893
cttccctttc tctgagaact ttcttcaaac ccatgggtaa aggatccaat atccatgttt     60

ctactacatg aggtattgca agctcctgca aacagttctt ggcttggagg tgaccatgta    120

gcccaattca ggattactga gaggcagtct ggagctgtgg cagccatctt gcccccgtga    180

ggggagagcc tgcttgagaa tggagccaat atggaggaag gcagagagag agagagaacg    240

atggcgggag atcagaccct gcctacggga tccagctaca tgtctggcct tctcagttcc    300

agaaaccaat gcatttcctg ttggatttct gtctcttata ccctcaatga tcc           353


<210>  8894
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8894

Met Phe Leu Leu His Glu Val Leu Gln Ala Pro Ala Asn Ser Ser Trp 
1               5                   10                  15


Leu Gly Gly Asp His Val Ala Gln Phe Arg Ile Thr Glu Arg Gln Ser 
            20                  25                  30


Gly Ala Val Ala Ala Ile Leu Pro Pro 
        35                  40


<210>  8895
<211>  1060
<212>  DNA
<213>  Homo sapiens

<400>  8895
cctgtaatcc cagcactttg ggaggctgag gtgggaggat tgcttgagtg cagcagtctg     60

aggccaacct ggacaacaca gtgagatcct atctctacaa aaaaaaattt aaaaattagc    120

cagatatggt ggtgcatgcc tgtagtccta gctgcttggg agggtgaggt catggggaaa    180

aggggattgc ttgagcccag gagttcaagg ttacagtgag ctgtgattgc accactgcac    240

tccagccctc gctgacagag caaaaccttg tctctaataa ataaataagt ttttttaaat    300

agggatagcc atgatggact acggtcattg caaaagccga atgaaattga tctgtgaaca    360

tgttttacac gttctgttgc tgtcaggcct ggggtggttt cagctcagca gatgttggtt    420

ccgcctgaca acttgacctg tggggttctg agtgttcgca agaatctccc cgccccacct    480

cccatcctct gtaccatctg cctcctgctt gcccacagca tggggttaac ggctgaagtt    540

gggcagcaaa gcctgaactg tgttttcctg ttggcagggc aaattcatcc gcatcaactt    600

cgacgtcacg ggttacatcg tgggagccaa cattgagacc tatctgctag aaaaatcacg    660

ggcaattcgc caagccagag acgagaggac attccacatc ttttactaca tgattgctgg    720

agccaaggag aagatgagaa gtaagtgact agcaatgaca tgtgattgga tggcttgagc    780

cttccctttc atcagaatcc ggggttaagg gattggctat taaaacagtc tcagatcctg    840

ccagaaagga ccatgtctgt gagtgacata tgaacagttc ttcatctcct cccaatgagt    900

gagtgtggct tgtgttcagt cattctcatt tactgagcac ctactatgtg acatagtagc    960

catcaactcc aattagacat tagatcatta atgattcatg tctcattaga ccagagagca   1020

tcaagtccaa ctagacacaa tctacgcctt caaggaaagg                         1060


<210>  8896
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  8896

Met Leu Val Pro Pro Asp Asn Leu Thr Cys Gly Val Leu Ser Val Arg 
1               5                   10                  15


Lys Asn Leu Pro Ala Pro Pro Pro Ile Leu Cys Thr Ile Cys Leu Leu 
            20                  25                  30


Leu Ala His Ser Met Gly Leu Thr Ala Glu Val Gly Gln Gln Ser Leu 
        35                  40                  45


Asn Cys Val Phe Leu Leu Ala Gly Gln Ile His Pro His Gln Leu Arg 
    50                  55                  60


Arg His Gly Leu His Arg Gly Ser Gln His 
65                  70


<210>  8897
<211>  2341
<212>  DNA
<213>  Homo sapiens

<400>  8897
agggagattt ggacgctccg gcctgggagg tgcgtcagat ccgagctcgc catccagttt     60

cctctccact agtcccccca gttggagatc tgggaccaac aaggcaccat ggcgcagaag    120

ggccaactca gtgacgatga gaagttcctc tttgtggaca aaaacttcat caacagccca    180

gtggcccagg ctgactgggc cgccaagaga ctcgtctggg tcccctcgga gaagcagggc    240

ttcgaggcag ccagcattaa ggaggagaag ggggatgagg tggttgtgga gctggtggag    300

aatggcaaga aggtcacggt tgggaaagat gacatccaga agatgaaccc acccaagttc    360

tccaaggtgg aggacatggc ggagctgacg tgcctcaacg aagcctccgt gctacacaac    420

ctgagggagc ggtacttctc agggctaata tatacgtact ctggcctctt ctgcgtggtg    480

gtcaacccct ataaacacct gcccatctac tcggagaaga tcgtcgacat gtacaagggc    540

aagaagaggc acgagatgcc gcctcacatc tacgccatcg cagacacggc ctaccggagc    600

atgcttcaag atcgggagga ccagtccatt ctatgcacag gcgagtctgg agccgggaaa    660

accgaaaaca ccaagaaggt cattcagtac ctggccgtgg tggcctcctc ccacaagggc    720

aagaaagaca caagtatcac ggtgagtggc agttcccaat cagaggccat gatttagcca    780

accggtctcc agcttgcagc ccaaccgaga tacaaacaga acatcattgc aagaactcag    840

gccccatctg actacccctc ccctgaagac tcaaagaggg accgtctttt tggcgagcag    900

gcctgttgag tgtgggtgat ttcttggctc agctagaagc atccctccag aagggggccc    960

gttttgtgaa atgagaataa gccctttcct tccatagcga gatcttcctc cacgtcgggg   1020

cttctcagtg gtggcactga tgtcattttg gaccagataa ctcttccttg gaggggcttc   1080

cctgtggctc gtagaatgtt tcacaacatc cctggcctcg acccgccaga tgccgacagc   1140

ccccttccct ccagttgtga caaccaaaaa tatctctaga cattgtcaga tgttccctgg   1200

ggtgggacag ttgcccttga ttgagaagca ctcctttcat gaatctctgt aacgtcccag   1260

gggttaaggt accttttggg ttcccggatt cctccacgtg tccccctgtc cctgggatgg   1320

agatgctggt atcactcggc ccgtgggctt cagtgcaatg ccattcagta actgtggatt   1380

gagcacctac tgtatgccag gaaccacttg gggtggggac ctggggataa gtctgagaga   1440

tgctgttatt ctcttctctg agcttccaga cctgtggaag agcatgtagt tgtcaaagaa   1500

tccctcaaat aaacagatga tgacacggta tgactaagag cttgggagga aaagaagagc   1560

aggtttctag agtcatcacc tctagggccc atccttctct tcctcctcgt gtgtcagccc   1620

tgccccatct atcccacagg agggggcacg tggtagggcc gctaggactg gccggtgcct   1680

ccgtctgcag gtttgtgggt gggaagatgg taggatggag atctgaccac ggcatggggt   1740

gtctccagtg ttcgccattc cagatgtcac tttgcgtcct cagaggggac tctggggcag   1800

ccaccatggc cggcttgtct ggaggccctt ggagatctag gatgggcgct ggtcgtggct   1860

ttggagaact ttccttctcc aaacaaatgc aggaaactca agattcagca tcctagaatt   1920

gtctctggca agttggtttc cagccatagt gagtgggaac aatggcccca gaggctgtgt   1980

ggcagtttaa acacagtttc cactgccttc cctttcccta aagagtaaac acaggagata   2040

atactttcta acaactcatc gttatcaagg gcctactatg tgctgcttgt tttggctgca   2100

tgcgtaaaca catctcagac attgtctcac tggatactgt tttaaggagc ctaatgtggc   2160

cccagtaatt atgaaaacct ttgaaatgtc tggatctcta agaaattaga aaaaggaggg   2220

aatggctgag catgggggct catgcctgta atctgtgttt tgggaggcca aggtgggagg   2280

atggtctgag cccaggagtt caggaccagc ctgggtgaca tagtgagacc ctgtctgtac   2340

c                                                                   2341


<210>  8898
<211>  222
<212>  PRT
<213>  Homo sapiens

<400>  8898

Met Ala Gln Lys Gly Gln Leu Ser Asp Asp Glu Lys Phe Leu Phe Val 
1               5                   10                  15


Asp Lys Asn Phe Ile Asn Ser Pro Val Ala Gln Ala Asp Trp Ala Ala 
            20                  25                  30


Lys Arg Leu Val Trp Val Pro Ser Glu Lys Gln Gly Phe Glu Ala Ala 
        35                  40                  45


Ser Ile Lys Glu Glu Lys Gly Asp Glu Val Val Val Glu Leu Val Glu 
    50                  55                  60


Asn Gly Lys Lys Val Thr Val Gly Lys Asp Asp Ile Gln Lys Met Asn 
65                  70                  75                  80


Pro Pro Lys Phe Ser Lys Val Glu Asp Met Ala Glu Leu Thr Cys Leu 
                85                  90                  95


Asn Glu Ala Ser Val Leu His Asn Leu Arg Glu Arg Tyr Phe Ser Gly 
            100                 105                 110


Leu Ile Tyr Thr Tyr Ser Gly Leu Phe Cys Val Val Val Asn Pro Tyr 
        115                 120                 125


Lys His Leu Pro Ile Tyr Ser Glu Lys Ile Val Asp Met Tyr Lys Gly 
    130                 135                 140


Lys Lys Arg His Glu Met Pro Pro His Ile Tyr Ala Ile Ala Asp Thr 
145                 150                 155                 160


Ala Tyr Arg Ser Met Leu Gln Asp Arg Glu Asp Gln Ser Ile Leu Cys 
                165                 170                 175


Thr Gly Glu Ser Gly Ala Gly Lys Thr Glu Asn Thr Lys Lys Val Ile 
            180                 185                 190


Gln Tyr Leu Ala Val Val Ala Ser Ser His Lys Gly Lys Lys Asp Thr 
        195                 200                 205


Ser Ile Thr Val Ser Gly Ser Ser Gln Ser Glu Ala Met Ile 
    210                 215                 220


<210>  8899
<211>  3370
<212>  DNA
<213>  Homo sapiens

<400>  8899
gctgggcgag tgacagcccc ggctccgcgc gccgcggccg ccagagccgg cgcaggggaa     60

gcgcccgcgg ccccgggtgc agcagcggcc gccgcctccc gcgcctcccc ggcccgcagc    120

ccgcggtccc gcggccccgg ggccggcacc tctcgggctc cggctccccg cgcgcaagat    180

ggctgacccg gctgcggggc cgccgccgag cgagggcgag gagagcaccg tgcgcttcgc    240

ccgcaaaggc gccctccggc agaagaacgt gcatgaggtc aagaaccaca aattcaccgc    300

ccgcttcttc aagcagccca ccttctgcag ccactgcacc gacttcatct ggggcttcgg    360

gaagcaggga ttccagtgcc aagtttgctg ctttgtggtg cacaagcggt gccatgaatt    420

tgtcacattc tcctgccctg gcgctgacaa gggtccagcc tccgatgacc cccgcagcaa    480

acacaagttt aagatccaca cgtactccag ccccacgttt tgtgaccact gtgggtcact    540

gctgtatgga ctcatccacc aggggatgaa atgtgacacc tgcatgatga atgtgcacaa    600

gcgctgcgtg atgaatgttc ccagcctgtg tggcacggac cacacggagc gccgcggccg    660

catctacatc caggcccaca tcgacaggga cgtcctcatt gtcctcgtaa gagatgctaa    720

aaaccttgta cctatggacc ccaatggcct gtcagatccc tacgtaaaac tgaaactgat    780

tcccgatccc aaaagtgaga gcaaacagaa gaccaaaacc atcaaatgct ccctcaaccc    840

tgagtggaat gagacattta gatttcagct gaaagaatcg gacaaagaca gaagactgtc    900

agtagagatt tgggattggg atttgaccag caggaatgac ttcatgggat ctttgtcctt    960

tgggatttct gaacttcaga aagccagtgt tgatggctgg tttaagttac tgagccagga   1020

ggaaggcgag tacttcaatg tgcctgtgcc accagaagga agtgaggcca atgaagaact   1080

gcggcagaaa tttgagaggg ccaagatcag tcagggaacc aaggtcccgg aagaaaagac   1140

gaccaacact gtctccaaat ttgacaacaa tggcaacaga gaccggatga aactgaccga   1200

ttttaacttc ctaatggtgc tggggaaagg cagctttggc aaggtcatgc tttcagaacg   1260

aaaaggcaca gatgagctct atgctgtgaa gatcctgaag aaggacgttg tgatccaaga   1320

tgatgacgtg gagtgcacta tggtggagaa gcgggtgttg gccctgcctg ggaagccgcc   1380

cttcctgacc cagctccact cctgcttcca gaccatggac cgcctgtact ttgtgatgga   1440

gtacgtgaat gggggcgacc tcatgtatca catccagcaa gtcggccggt tcaaggagcc   1500

ccatgctgta ttttacgctg cagaaattgc catcggtctg ttcttcttac agagtaaggg   1560

catcatttac cgtgacctaa aacttgacaa cgtgatgctc gattctgagg gacacatcaa   1620

gattgccgat tttggcatgt gtaaggaaaa catctgggat ggggtgacaa ccaagacatt   1680

ctgtggcact ccagactaca tcgcccccga gataattgct tatcagccct atgggaagtc   1740

cgtggattgg tgggcatttg gagtcctgct gtatgaaatg ttggctgggc aggcaccctt   1800

tgaaggggag gatgaagatg aactcttcca atccatcatg gaacacaacg tagcctatcc   1860

caagtctatg tccaaggaag ctgtggccat ctgcaaaggg ctgatgacca aacacccagg   1920

caaacgtctg ggttgtggac ctgaaggcga acgtgatatc aaagagcatg catttttccg   1980

gtatattgat tgggagaaac ttgaacgcaa agagatccag cccccttata agccaaaagc   2040

ttgtgggcga aatgctgaaa acttcgaccg atttttcacc cgccatccac cagtcctaac   2100

acctcccgac caggaagtca tcaggaatat tgaccaatca gaattcgaag gattttcctt   2160

tgttaactct gaatttttaa aacccgaagt caagagctaa gtagatgtgt agatctccgt   2220

ccttcatttc tgtcattcaa gctcaacggc tattgtggtg acatttttat gtttttcatt   2280

gccaagttgc atccatgttt gattttctga tgagactaga gtgacagtgt ttcagaaccc   2340

aaatgtcctc aggtagtttg gagcatctct atgagatggg attatgcaga tggcctatgg   2400

aaaatgcagc tgcataatta acacattatc aaagtcctct tacaatttat tttccgcagc   2460

atgtcagcta agtagaccca atggggagag aaaatgcctg ctttctttcc ctctttttct   2520

gcactgccat attcaccccc aaccatccaa tctgtggata attggatgtt agcggtactc   2580

ttccacttcc gggcctggag cttggcttgt atccaagtgt atggttgctt tgcctaagag   2640

gaatccctct atttcacctg ttctggaggc accagacctt gaaaagaaca tgctcaaaat   2700

aaaatgttat ctgttatttt tgtaaactca aagttaagat gatcaaagtt ctaaaattcc   2760

aagaatgtgc ttttagacgg tctcaatcta aaagcacttc aaggggtcaa agggcaacca   2820

gcttgggtgc tacctcagtg ttgtagtttc tgatacttta tgtctttgct caccctcatc   2880

cccaaactac ttgaaaaggg catttggcac cactctctga aacaacacag tcactctagc   2940

aaggccccca aagggccctg gttttacatt acatttcaaa ctttatttgc tttggggttt   3000

tgtttctgtt gttgttcaaa tgcaaaaaaa agaaaaaaaa agaaaaaaaa aggtgactca   3060

cattgttaca catgctttaa aatatgtatt caaatgttat taaccacaat gacgacctgc   3120

tttgatttaa ccaagaagac ggctgcggag cctagcagac tcaggcctgt gggaatggga   3180

tttgttacaa atctaggttt gttactggct tcagaaagct aattaagtgc tctgaaaaag   3240

acaccgtttc ttgaaacaaa gatggttgta ttcctcactt tgatgttgtt ttgcaagatg   3300

tttgtggaaa tgttcatttg tatctggatc tctgttatgt gccatttttc ttctagcatc   3360

gagatacaat                                                          3370


<210>  8900
<211>  673
<212>  PRT
<213>  Homo sapiens

<400>  8900

Met Ala Asp Pro Ala Ala Gly Pro Pro Pro Ser Glu Gly Glu Glu Ser 
1               5                   10                  15


Thr Val Arg Phe Ala Arg Lys Gly Ala Leu Arg Gln Lys Asn Val His 
            20                  25                  30


Glu Val Lys Asn His Lys Phe Thr Ala Arg Phe Phe Lys Gln Pro Thr 
        35                  40                  45


Phe Cys Ser His Cys Thr Asp Phe Ile Trp Gly Phe Gly Lys Gln Gly 
    50                  55                  60


Phe Gln Cys Gln Val Cys Cys Phe Val Val His Lys Arg Cys His Glu 
65                  70                  75                  80


Phe Val Thr Phe Ser Cys Pro Gly Ala Asp Lys Gly Pro Ala Ser Asp 
                85                  90                  95


Asp Pro Arg Ser Lys His Lys Phe Lys Ile His Thr Tyr Ser Ser Pro 
            100                 105                 110


Thr Phe Cys Asp His Cys Gly Ser Leu Leu Tyr Gly Leu Ile His Gln 
        115                 120                 125


Gly Met Lys Cys Asp Thr Cys Met Met Asn Val His Lys Arg Cys Val 
    130                 135                 140


Met Asn Val Pro Ser Leu Cys Gly Thr Asp His Thr Glu Arg Arg Gly 
145                 150                 155                 160


Arg Ile Tyr Ile Gln Ala His Ile Asp Arg Asp Val Leu Ile Val Leu 
                165                 170                 175


Val Arg Asp Ala Lys Asn Leu Val Pro Met Asp Pro Asn Gly Leu Ser 
            180                 185                 190


Asp Pro Tyr Val Lys Leu Lys Leu Ile Pro Asp Pro Lys Ser Glu Ser 
        195                 200                 205


Lys Gln Lys Thr Lys Thr Ile Lys Cys Ser Leu Asn Pro Glu Trp Asn 
    210                 215                 220


Glu Thr Phe Arg Phe Gln Leu Lys Glu Ser Asp Lys Asp Arg Arg Leu 
225                 230                 235                 240


Ser Val Glu Ile Trp Asp Trp Asp Leu Thr Ser Arg Asn Asp Phe Met 
                245                 250                 255


Gly Ser Leu Ser Phe Gly Ile Ser Glu Leu Gln Lys Ala Ser Val Asp 
            260                 265                 270


Gly Trp Phe Lys Leu Leu Ser Gln Glu Glu Gly Glu Tyr Phe Asn Val 
        275                 280                 285


Pro Val Pro Pro Glu Gly Ser Glu Ala Asn Glu Glu Leu Arg Gln Lys 
    290                 295                 300


Phe Glu Arg Ala Lys Ile Ser Gln Gly Thr Lys Val Pro Glu Glu Lys 
305                 310                 315                 320


Thr Thr Asn Thr Val Ser Lys Phe Asp Asn Asn Gly Asn Arg Asp Arg 
                325                 330                 335


Met Lys Leu Thr Asp Phe Asn Phe Leu Met Val Leu Gly Lys Gly Ser 
            340                 345                 350


Phe Gly Lys Val Met Leu Ser Glu Arg Lys Gly Thr Asp Glu Leu Tyr 
        355                 360                 365


Ala Val Lys Ile Leu Lys Lys Asp Val Val Ile Gln Asp Asp Asp Val 
    370                 375                 380


Glu Cys Thr Met Val Glu Lys Arg Val Leu Ala Leu Pro Gly Lys Pro 
385                 390                 395                 400


Pro Phe Leu Thr Gln Leu His Ser Cys Phe Gln Thr Met Asp Arg Leu 
                405                 410                 415


Tyr Phe Val Met Glu Tyr Val Asn Gly Gly Asp Leu Met Tyr His Ile 
            420                 425                 430


Gln Gln Val Gly Arg Phe Lys Glu Pro His Ala Val Phe Tyr Ala Ala 
        435                 440                 445


Glu Ile Ala Ile Gly Leu Phe Phe Leu Gln Ser Lys Gly Ile Ile Tyr 
    450                 455                 460


Arg Asp Leu Lys Leu Asp Asn Val Met Leu Asp Ser Glu Gly His Ile 
465                 470                 475                 480


Lys Ile Ala Asp Phe Gly Met Cys Lys Glu Asn Ile Trp Asp Gly Val 
                485                 490                 495


Thr Thr Lys Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro Glu Ile 
            500                 505                 510


Ile Ala Tyr Gln Pro Tyr Gly Lys Ser Val Asp Trp Trp Ala Phe Gly 
        515                 520                 525


Val Leu Leu Tyr Glu Met Leu Ala Gly Gln Ala Pro Phe Glu Gly Glu 
    530                 535                 540


Asp Glu Asp Glu Leu Phe Gln Ser Ile Met Glu His Asn Val Ala Tyr 
545                 550                 555                 560


Pro Lys Ser Met Ser Lys Glu Ala Val Ala Ile Cys Lys Gly Leu Met 
                565                 570                 575


Thr Lys His Pro Gly Lys Arg Leu Gly Cys Gly Pro Glu Gly Glu Arg 
            580                 585                 590


Asp Ile Lys Glu His Ala Phe Phe Arg Tyr Ile Asp Trp Glu Lys Leu 
        595                 600                 605


Glu Arg Lys Glu Ile Gln Pro Pro Tyr Lys Pro Lys Ala Cys Gly Arg 
    610                 615                 620


Asn Ala Glu Asn Phe Asp Arg Phe Phe Thr Arg His Pro Pro Val Leu 
625                 630                 635                 640


Thr Pro Pro Asp Gln Glu Val Ile Arg Asn Ile Asp Gln Ser Glu Phe 
                645                 650                 655


Glu Gly Phe Ser Phe Val Asn Ser Glu Phe Leu Lys Pro Glu Val Lys 
            660                 665                 670


Ser 



<210>  8901
<211>  7995
<212>  DNA
<213>  Homo sapiens

<400>  8901
gctgggcgag tgacagcccc ggctccgcgc gccgcggccg ccagagccgg cgcaggggaa     60

gcgcccgcgg ccccgggtgc agcagcggcc gccgcctccc gcgcctcccc ggcccgcagc    120

ccgcggtccc gcggccccgg ggccggcacc tctcgggctc cggctccccg cgcgcaagat    180

ggctgacccg gctgcggggc cgccgccgag cgagggcgag gagagcaccg tgcgcttcgc    240

ccgcaaaggc gccctccggc agaagaacgt gcatgaggtc aagaaccaca aattcaccgc    300

ccgcttcttc aagcagccca ccttctgcag ccactgcacc gacttcatct ggggcttcgg    360

gaagcaggga ttccagtgcc aagtttgctg ctttgtggtg cacaagcggt gccatgaatt    420

tgtcacattc tcctgccctg gcgctgacaa gggtccagcc tccgatgacc cccgcagcaa    480

acacaagttt aagatccaca cgtactccag ccccacgttt tgtgaccact gtgggtcact    540

gctgtatgga ctcatccacc aggggatgaa atgtgacacc tgcatgatga atgtgcacaa    600

gcgctgcgtg atgaatgttc ccagcctgtg tggcacggac cacacggagc gccgcggccg    660

catctacatc caggcccaca tcgacaggga cgtcctcatt gtcctcgtaa gagatgctaa    720

aaaccttgta cctatggacc ccaatggcct gtcagatccc tacgtaaaac tgaaactgat    780

tcccgatccc aaaagtgaga gcaaacagaa gaccaaaacc atcaaatgct ccctcaaccc    840

tgagtggaat gagacattta gatttcagct gaaagaatcg gacaaagaca gaagactgtc    900

agtagagatt tgggattggg atttgaccag caggaatgac ttcatgggat ctttgtcctt    960

tgggatttct gaacttcaga aagccagtgt tgatggctgg tttaagttac tgagccagga   1020

ggaaggcgag tacttcaatg tgcctgtgcc accagaagga agtgaggcca atgaagaact   1080

gcggcagaaa tttgagaggg ccaagatcag tcagggaacc aaggtcccgg aagaaaagac   1140

gaccaacact gtctccaaat ttgacaacaa tggcaacaga gaccggatga aactgaccga   1200

ttttaacttc ctaatggtgc tggggaaagg cagctttggc aaggtcatgc tttcagaacg   1260

aaaaggcaca gatgagctct atgctgtgaa gatcctgaag aaggacgttg tgatccaaga   1320

tgatgacgtg gagtgcacta tggtggagaa gcgggtgttg gccctgcctg ggaagccgcc   1380

cttcctgacc cagctccact cctgcttcca gaccatggac cgcctgtact ttgtgatgga   1440

gtacgtgaat gggggcgacc tcatgtatca catccagcaa gtcggccggt tcaaggagcc   1500

ccatgctgta ttttacgctg cagaaattgc catcggtctg ttcttcttac agagtaaggg   1560

catcatttac cgtgacctaa aacttgacaa cgtgatgctc gattctgagg gacacatcaa   1620

gattgccgat tttggcatgt gtaaggaaaa catctgggat ggggtgacaa ccaagacatt   1680

ctgtggcact ccagactaca tcgcccccga gataattgct tatcagccct atgggaagtc   1740

cgtggattgg tgggcatttg gagtcctgct gtatgaaatg ttggctgggc aggcaccctt   1800

tgaaggggag gatgaagatg aactcttcca atccatcatg gaacacaacg tagcctatcc   1860

caagtctatg tccaaggaag ctgtggccat ctgcaaaggg ctgatgacca aacacccagg   1920

caaacgtctg ggttgtggac ctgaaggcga acgtgatatc aaagagcatg catttttccg   1980

gtatattgat tgggagaaac ttgaacgcaa agagatccag cccccttata agccaaaagc   2040

ttgtgggcga aatgctgaaa acttcgaccg atttttcacc cgccatccac cagtcctaac   2100

acctcccgac caggaagtca tcaggaatat tgaccaatca gaattcgaag gattttcctt   2160

tgttaactct gaatttttaa aacccgaagt caagagctaa gtagatgtgt agatctccgt   2220

ccttcatttc tgtcattcaa gctcaacggc tattgtggtg acatttttat gtttttcatt   2280

gccaagttgc atccatgttt gattttctga tgagactaga gtgacagtgt ttcagaaccc   2340

aaatgtcctc aggtagtttg gagcatctct atgagatggg attatgcaga tggcctatgg   2400

aaaatgcagc tgcataatta acacattatc aaagtcctct tacaatttat tttccgcagc   2460

atgtcagcta agtagaccca atggggagag aaaatgcctg ctttctttcc ctctttttct   2520

gcactgccat attcaccccc aaccatccaa tctgtggata attggatgtt agcggtactc   2580

ttccacttcc gggcctggag cttggcttgt atccaagtgt atggttgctt tgcctaagag   2640

gaatccctct atttcacctg ttctggaggc accagacctt gaaaagaaca tgctcaaaat   2700

aaaatgttat ctgttatttt tgtaaactca aagttaagat gatcaaagtt ctaaaattcc   2760

aagaatgtgc ttttagacgg tctcaatcta aaagcacttc aaggggtcaa agggcaacca   2820

gcttgggtgc tacctcagtg ttgtagtttc tgatacttta tgtctttgct caccctcatc   2880

cccaaactac ttgaaaaggg catttggcac cactctctga aacaacacag tcactctagc   2940

aaggccccca aagggccctg gttttacatt acatttcaaa ctttatttgc tttggggttt   3000

tgtttctgtt gttgttcaaa tgcaaaaaaa agaaaaaaaa agaaaaaaaa aggtgactca   3060

cattgttaca catgctttaa aatatgtatt caaatgttat taaccacaat gacgacctgc   3120

tttgatttaa ccaagaagac ggctgcggag cctagcagac tcaggcctgt gggaatggga   3180

tttgttacaa atctaggttt gttactggct tcagaaagct aattaagtgc tctgaaaaag   3240

acaccgtttc ttgaaacaaa gatggttgta ttcctcactt tgatgttgtt ttgcaagatg   3300

tttgtggaaa tgttcatttg tatctggatc tctgttatgt gccatttttc ttctagcatc   3360

gagatacaat aaaaaaaaaa aaaaagaaaa gaagaagaaa tactatttca aggaaaactg   3420

ctctttttga gaaacgtgga cctaaactac aaagtgggaa ctgaggaggg aactcaggag   3480

aaaggaacta actgcggagc tttaatcttg gccccagtgt tcagccactc ggaggggcgg   3540

gggctgtggc ccattcaggg gctgctggtg ggctgtagtg gggtgggatg acctggccag   3600

agccaacgag gatactggag cccaaagtca agtttagaga ccagctggga acgtgaatgg   3660

ggctcttgat tttcttatca aaatcaccac tcctcccagc ttggactaaa tattctttct   3720

agcaagcagc tttgtgagct ccctgaagcc caaggaaacc cttcggtggg agaaatttca   3780

tttctgtctg agaggattaa ggcagcaggt gactccccct cctcgcctgc cgtgtcctgc   3840

tattctcagg cagctctaag gagaattctt atcacagttc aagtgatttc cagaagttcc   3900

agggcttctg agagaccatc aagggaactt taacaacttg acaaatgtcc ttgaagtaag   3960

atgcctcatc tttagggaaa aatggggttt ggatttctgc ttaggcaaag tctcctgcag   4020

ttcatccttc tctgtcctct tcttgcttca ggcttgggga ccgtccctgc tgtccccact   4080

gtggtggcaa tcaggaccta aggtgaagca aacttgaagt tctatctgac aagtttaggc   4140

agtaagagaa ggagggaaat cggagcaaag ctccctcact ttattgttga gaaactggca   4200

tctggaaaga ggaaggaatt tgcccaaagt cagtcagctg ggataaaaac ctgggtgtcc   4260

tgtccagaaa gtgcagggtg ctttctgctc tgtagcaagg cagcagacat ctctgagcca   4320

ggcccaccaa caggccctta tctggtggtt ggatcatgat cccattttgc ttggacatgc   4380

tctcaggaag ataaaaacca tggagaaaca ctaggccatt gacaaatgat ctgagacaac   4440

tttagaaaac aatgtaggat gaatggaaag agaaagaaag gaaagaaaga agaaaaagaa   4500

agaaggaaag aaagaaagag aaaggaagga aggaaagaag gaaggaaaag aaggaaggaa   4560

ggaaggaata tagtgttata aatactgcac tcaacatttt ccaaattctt gccattattt   4620

ttcaaaagtt taatagtttg cagaaataga tactcaagcc aaagtctgtt ttagagaaac   4680

tttccatgga aagtcagaat ttctaccact tccttttcta tccacatttc cagtgcagaa   4740

gaaactgaga aacagagctt tttgaagaga ggacagggcc atagcaacaa ggaccttctt   4800

gggggattaa tgggaggtca gtagaattaa taaccctcct tggatgagtg ctactgtttt   4860

cacatggctt cagatgctat caacctcaaa gaaatgatct caacagagaa gcttattctc   4920

tcccaacttc tacggtaaaa tccaggagta ttttctctgg ggatctgccc acaggacaaa   4980

gtccataaaa gcaagtcctg tctggaccat gtggttatct gaagcattag ccatcaccag   5040

cacaacaaac ggggcagggc tttccaaggt ggggctggtc agaagggaat ctttgataag   5100

aggcccacag gcagggaaag cgaaataggg ttgatgagac caggggagac ctaaaaaaaa   5160

ggcagctttg tgtcttctag ctccaaatat acctgccttt tagctcacac actgtcctgg   5220

agttctcaga cctttagggg ccctaacaca gttcagttca tacaggggtt caaaagggac   5280

agtggcccat ttgggagacc tttaggatca atgggaatca attccattgt tttgcctcag   5340

agtaaagttt ctggctcggg gacaattata agttgcaaaa aggatagagg catatcccaa   5400

gtcttccttc attccacaaa taattacaaa caacctactg tgtgccaggc actattctta   5460

gcactggaaa tacactagtg aagaagcaga tgaggaccct gtttattgtt tctctccaag   5520

aaattctcca agaatattgt ttcttggaga gaaataataa ataaacaaga caatttctga   5580

aagcaataag tgcaatcaag ataattaaag gatgctaaag tgtgacttgt ggggattggg   5640

agagagatgc acagacaata ttaaagagga ggcattcgag ctttgttgtg aacaccggaa   5700

gtaacatgcc gagcgcctgg gggatggaaa ctcctatagc accccacagg ctaacagcaa   5760

gcaggacaag acaaaaaggg caggtgggac atggtagaga tggaccctac ccaggaaaca   5820

gctccatcag catcttagcc tgccccactc tagccacaca tacccacgtg tgctcctgag   5880

ttcagtgtgc ccacctcact cccacaccct cacatagact tggcaagagt aaggagggaa   5940

ctccatagag acattttacc tatctcaggg gagcagccac aaagaagcaa gtcttgtaaa   6000

aggtcttttg caaaggagag tgaacccagc aatgagagat ccttaacagc tagtgcccat   6060

tagggggcta aacctaaagc ctgggtggtg atggctcaaa cgctaatgag tcagtgaatc   6120

cttaccgacc ccctggcctt tataatctga ggcaactttg gctgcagccc gggaatgtgc   6180

agggcactag ggaatacaag gccttcttcc ctggttgtct tgtaataaaa cagccatggg   6240

gttgtccctc cagtccgaga gactgtgatg aggcctacat agcagcgatg tggtcaggta   6300

aaaatcagga acccactgaa atcttgggca agccaccctg cctgcttgtg cctcggttct   6360

ctcatatgtc atatatagga ggtgaggact ccagctccac ctgccccagg tgggtgtggt   6420

gatgatgagg aaagacaaga ggcttgcaag gaccctgaag aggtcggagc atcatacaga   6480

ttcctttatt agcccacatt ctgatgttcc ctggtgagac ttgccccaag caattgctag   6540

taaatggggg ttaatttctt ctccacctcc ctactgaaca aaaaaagaaa tgccagactt   6600

actaggagaa tcgagttgct ttgagtttct tttgttttgt tttgttttgt tttgttttaa   6660

ggctcccctt acacaccctc ctttaagctt tgggttttct ctcttatagt ttgttgacac   6720

atgctaaaaa tgtctttgga gagaacttct gcctgataaa cacccaattc tagactgtgg   6780

gtggattttc gagctgacgg tggtcaattc ctttcattaa gcagtgatct gatttctcca   6840

catggccatt ctgccttctt gggggcagag tagatgggca gcagttcacc ttttcagaga   6900

aagaggtctt ctagccacct gggctgctac tgaatggttt tctccaggac gctctaccta   6960

atgattattt ctataacatt aagcatggta ataagtagct tccaattcaa ttcatcctaa   7020

agccaaagaa aatacagcaa cacacacaca cacacacaca cacacacaca cacacacaca   7080

cacacaccac tttatggcaa ttcttaactg acattcaatg acttacttct tttcttagaa   7140

aatttccacc acatttctat ccccaagcca acatacaatg tgaaatgaaa gccagtgcgt   7200

ggagtgcagc tgctaaaaat tttcagcaca gggctctttc tgactctgct catgagatgg   7260

tatcagccac ccaatgactg gcgtatcttg gtcctgtgtc tttcttctta cgctgtgtta   7320

atgtgtttac tttccatttg gcagagagac aagagagaca cctccaactt cgacaaagag   7380

ttcaccagac agcctgtgga actgaccccc actgataaac tcttcatcat gaacttggac   7440

caaaatgaat ttgctggctt ctcttatact aacccagagt ttgtcattaa tgtgtaggtg   7500

aatgcaaact ccatcgttga gcctggggtg taagacttca agccaagcgt atgtatcaat   7560

tctagtcttc caggattcac ggtgcacatg ctggcattca acatgtggaa agcttgtctt   7620

agagggcttt tctttgtatg tgtagcttgc tagtttgttt tctacatttg aaaatgttta   7680

gtttagaata agcgcattat ccaattatag aggtacaatt ttccaaactt ccagaaactc   7740

atcaaatgaa cagacaatgt caaaactact gtgtctgata ccaaaatgct tcagtatttg   7800

taatttttca agtcagaagc tgatgttcct ggtaaaagtt tttacagtta ttctataata   7860

tcttctttga atgctaagca tgagcgatat ttttaaaaat tgtgagtaag ctttgcagtt   7920

actgtgaact attgtctctt ggaggaagtt ttttgtttaa gaattgatat gattaaactg   7980

aattaatata tgcaa                                                    7995


<210>  8902
<211>  673
<212>  PRT
<213>  Homo sapiens

<400>  8902

Met Ala Asp Pro Ala Ala Gly Pro Pro Pro Ser Glu Gly Glu Glu Ser 
1               5                   10                  15


Thr Val Arg Phe Ala Arg Lys Gly Ala Leu Arg Gln Lys Asn Val His 
            20                  25                  30


Glu Val Lys Asn His Lys Phe Thr Ala Arg Phe Phe Lys Gln Pro Thr 
        35                  40                  45


Phe Cys Ser His Cys Thr Asp Phe Ile Trp Gly Phe Gly Lys Gln Gly 
    50                  55                  60


Phe Gln Cys Gln Val Cys Cys Phe Val Val His Lys Arg Cys His Glu 
65                  70                  75                  80


Phe Val Thr Phe Ser Cys Pro Gly Ala Asp Lys Gly Pro Ala Ser Asp 
                85                  90                  95


Asp Pro Arg Ser Lys His Lys Phe Lys Ile His Thr Tyr Ser Ser Pro 
            100                 105                 110


Thr Phe Cys Asp His Cys Gly Ser Leu Leu Tyr Gly Leu Ile His Gln 
        115                 120                 125


Gly Met Lys Cys Asp Thr Cys Met Met Asn Val His Lys Arg Cys Val 
    130                 135                 140


Met Asn Val Pro Ser Leu Cys Gly Thr Asp His Thr Glu Arg Arg Gly 
145                 150                 155                 160


Arg Ile Tyr Ile Gln Ala His Ile Asp Arg Asp Val Leu Ile Val Leu 
                165                 170                 175


Val Arg Asp Ala Lys Asn Leu Val Pro Met Asp Pro Asn Gly Leu Ser 
            180                 185                 190


Asp Pro Tyr Val Lys Leu Lys Leu Ile Pro Asp Pro Lys Ser Glu Ser 
        195                 200                 205


Lys Gln Lys Thr Lys Thr Ile Lys Cys Ser Leu Asn Pro Glu Trp Asn 
    210                 215                 220


Glu Thr Phe Arg Phe Gln Leu Lys Glu Ser Asp Lys Asp Arg Arg Leu 
225                 230                 235                 240


Ser Val Glu Ile Trp Asp Trp Asp Leu Thr Ser Arg Asn Asp Phe Met 
                245                 250                 255


Gly Ser Leu Ser Phe Gly Ile Ser Glu Leu Gln Lys Ala Ser Val Asp 
            260                 265                 270


Gly Trp Phe Lys Leu Leu Ser Gln Glu Glu Gly Glu Tyr Phe Asn Val 
        275                 280                 285


Pro Val Pro Pro Glu Gly Ser Glu Ala Asn Glu Glu Leu Arg Gln Lys 
    290                 295                 300


Phe Glu Arg Ala Lys Ile Ser Gln Gly Thr Lys Val Pro Glu Glu Lys 
305                 310                 315                 320


Thr Thr Asn Thr Val Ser Lys Phe Asp Asn Asn Gly Asn Arg Asp Arg 
                325                 330                 335


Met Lys Leu Thr Asp Phe Asn Phe Leu Met Val Leu Gly Lys Gly Ser 
            340                 345                 350


Phe Gly Lys Val Met Leu Ser Glu Arg Lys Gly Thr Asp Glu Leu Tyr 
        355                 360                 365


Ala Val Lys Ile Leu Lys Lys Asp Val Val Ile Gln Asp Asp Asp Val 
    370                 375                 380


Glu Cys Thr Met Val Glu Lys Arg Val Leu Ala Leu Pro Gly Lys Pro 
385                 390                 395                 400


Pro Phe Leu Thr Gln Leu His Ser Cys Phe Gln Thr Met Asp Arg Leu 
                405                 410                 415


Tyr Phe Val Met Glu Tyr Val Asn Gly Gly Asp Leu Met Tyr His Ile 
            420                 425                 430


Gln Gln Val Gly Arg Phe Lys Glu Pro His Ala Val Phe Tyr Ala Ala 
        435                 440                 445


Glu Ile Ala Ile Gly Leu Phe Phe Leu Gln Ser Lys Gly Ile Ile Tyr 
    450                 455                 460


Arg Asp Leu Lys Leu Asp Asn Val Met Leu Asp Ser Glu Gly His Ile 
465                 470                 475                 480


Lys Ile Ala Asp Phe Gly Met Cys Lys Glu Asn Ile Trp Asp Gly Val 
                485                 490                 495


Thr Thr Lys Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro Glu Ile 
            500                 505                 510


Ile Ala Tyr Gln Pro Tyr Gly Lys Ser Val Asp Trp Trp Ala Phe Gly 
        515                 520                 525


Val Leu Leu Tyr Glu Met Leu Ala Gly Gln Ala Pro Phe Glu Gly Glu 
    530                 535                 540


Asp Glu Asp Glu Leu Phe Gln Ser Ile Met Glu His Asn Val Ala Tyr 
545                 550                 555                 560


Pro Lys Ser Met Ser Lys Glu Ala Val Ala Ile Cys Lys Gly Leu Met 
                565                 570                 575


Thr Lys His Pro Gly Lys Arg Leu Gly Cys Gly Pro Glu Gly Glu Arg 
            580                 585                 590


Asp Ile Lys Glu His Ala Phe Phe Arg Tyr Ile Asp Trp Glu Lys Leu 
        595                 600                 605


Glu Arg Lys Glu Ile Gln Pro Pro Tyr Lys Pro Lys Ala Cys Gly Arg 
    610                 615                 620


Asn Ala Glu Asn Phe Asp Arg Phe Phe Thr Arg His Pro Pro Val Leu 
625                 630                 635                 640


Thr Pro Pro Asp Gln Glu Val Ile Arg Asn Ile Asp Gln Ser Glu Phe 
                645                 650                 655


Glu Gly Phe Ser Phe Val Asn Ser Glu Phe Leu Lys Pro Glu Val Lys 
            660                 665                 670


Ser 



<210>  8903
<211>  2692
<212>  DNA
<213>  Homo sapiens

<400>  8903
gctgggcgag tgacagcccc ggctccgcgc gccgcggccg ccagagccgg cgcaggggaa     60

gcgcccgcgg ccccgggtgc agcagcggcc gccgcctccc gcgcctcccc ggcccgcagc    120

ccgcggtccc gcggccccgg ggccggcacc tctcgggctc cggctccccg cgcgcaagat    180

ggctgacccg gctgcggggc cgccgccgag cgagggcgag gagagcaccg tgcgcttcgc    240

ccgcaaaggc gccctccggc agaagaacgt gcatgaggtc aagaaccaca aattcaccgc    300

ccgcttcttc aagcagccca ccttctgcag ccactgcacc gacttcatct ggggcttcgg    360

gaagcaggga ttccagtgcc aagtttgctg ctttgtggtg cacaagcggt gccatgaatt    420

tgtcacattc tcctgccctg gcgctgacaa gggtccagcc tccgatgacc cccgcagcaa    480

acacaagttt aagatccaca cgtactccag ccccacgttt tgtgaccact gtgggtcact    540

gctgtatgga ctcatccacc aggggatgaa atgtgacacc tgcatgatga atgtgcacaa    600

gcgctgcgtg atgaatgttc ccagcctgtg tggcacggac cacacggagc gccgcggccg    660

catctacatc caggcccaca tcgacaggga cgtcctcatt gtcctcgtaa gagatgctaa    720

aaaccttgta cctatggacc ccaatggcct gtcagatccc tacgtaaaac tgaaactgat    780

tcccgatccc aaaagtgaga gcaaacagaa gaccaaaacc atcaaatgct ccctcaaccc    840

tgagtggaat gagacattta gatttcagct gaaagaatcg gacaaagaca gaagactgtc    900

agtagagatt tgggattggg atttgaccag caggaatgac ttcatgggat ctttgtcctt    960

tgggatttct gaacttcaga aagccagtgt tgatggctgg tttaagttac tgagccagga   1020

ggaaggcgag tacttcaatg tgcctgtgcc accagaagga agtgaggcca atgaagaact   1080

gcggcagaaa tttgagaggg ccaagatcag tcagggaacc aaggtcccgg aagaaaagac   1140

gaccaacact gtctccaaat ttgacaacaa tggcaacaga gaccggatga aactgaccga   1200

ttttaacttc ctaatggtgc tggggaaagg cagctttggc aaggtcatgc tttcagaacg   1260

aaaaggcaca gatgagctct atgctgtgaa gatcctgaag aaggacgttg tgatccaaga   1320

tgatgacgtg gagtgcacta tggtggagaa gcgggtgttg gccctgcctg ggaagccgcc   1380

cttcctgacc cagctccact cctgcttcca gaccatggac cgcctgtact ttgtgatgga   1440

gtacgtgaat gggggcgacc tcatgtatca catccagcaa gtcggccggt tcaaggagcc   1500

ccatgctgta ttttacgctg cagaaattgc catcggtctg ttcttcttac agagtaaggg   1560

catcatttac cgtgacctaa aacttgacaa cgtgatgctc gattctgagg gacacatcaa   1620

gattgccgat tttggcatgt gtaaggaaaa catctgggat ggggtgacaa ccaagacatt   1680

ctgtggcact ccagactaca tcgcccccga gataattgct tatcagccct atgggaagtc   1740

cgtggattgg tgggcatttg gagtcctgct gtatgaaatg ttggctgggc aggcaccctt   1800

tgaaggggag gatgaagatg aactcttcca atccatcatg gaacacaacg tagcctatcc   1860

caagtctatg tccaaggaag ctgtggccat ctgcaaaggg ctgatgacca aacacccagg   1920

caaacgtctg ggttgtggac ctgaaggcga acgtgatatc aaagagcatg catttttccg   1980

gtatattgat tgggagaaac ttgaacgcaa agagatccag cccccttata agccaaaagc   2040

tagagacaag agagacacct ccaacttcga caaagagttc accagacagc ctgtggaact   2100

gacccccact gataaactct tcatcatgaa cttggaccaa aatgaatttg ctggcttctc   2160

ttatactaac ccagagtttg tcattaatgt gtaggtgaat gcaaactcca tcgttgagcc   2220

tggggtgtaa gacttcaagc caagcgtatg tatcaattct agtcttccag gattcacggt   2280

gcacatgctg gcattcaaca tgtggaaagc ttgtcttaga gggcttttct ttgtatgtgt   2340

agcttgctag tttgttttct acatttgaaa atgtttagtt tagaataagc gcattatcca   2400

attatagagg tacaattttc caaacttcca gaaactcatc aaatgaacag acaatgtcaa   2460

aactactgtg tctgatacca aaatgcttca gtatttgtaa tttttcaagt cagaagctga   2520

tgttcctggt aaaagttttt acagttattc tataatatct tctttgaatg ctaagcatga   2580

gcgatatttt taaaaattgt gagtaagctt tgcagttact gtgaactatt gtctcttgga   2640

ggaagttttt tgtttaagaa ttgatatgat taaactgaat taatatatgc aa           2692


<210>  8904
<211>  671
<212>  PRT
<213>  Homo sapiens

<400>  8904

Met Ala Asp Pro Ala Ala Gly Pro Pro Pro Ser Glu Gly Glu Glu Ser 
1               5                   10                  15


Thr Val Arg Phe Ala Arg Lys Gly Ala Leu Arg Gln Lys Asn Val His 
            20                  25                  30


Glu Val Lys Asn His Lys Phe Thr Ala Arg Phe Phe Lys Gln Pro Thr 
        35                  40                  45


Phe Cys Ser His Cys Thr Asp Phe Ile Trp Gly Phe Gly Lys Gln Gly 
    50                  55                  60


Phe Gln Cys Gln Val Cys Cys Phe Val Val His Lys Arg Cys His Glu 
65                  70                  75                  80


Phe Val Thr Phe Ser Cys Pro Gly Ala Asp Lys Gly Pro Ala Ser Asp 
                85                  90                  95


Asp Pro Arg Ser Lys His Lys Phe Lys Ile His Thr Tyr Ser Ser Pro 
            100                 105                 110


Thr Phe Cys Asp His Cys Gly Ser Leu Leu Tyr Gly Leu Ile His Gln 
        115                 120                 125


Gly Met Lys Cys Asp Thr Cys Met Met Asn Val His Lys Arg Cys Val 
    130                 135                 140


Met Asn Val Pro Ser Leu Cys Gly Thr Asp His Thr Glu Arg Arg Gly 
145                 150                 155                 160


Arg Ile Tyr Ile Gln Ala His Ile Asp Arg Asp Val Leu Ile Val Leu 
                165                 170                 175


Val Arg Asp Ala Lys Asn Leu Val Pro Met Asp Pro Asn Gly Leu Ser 
            180                 185                 190


Asp Pro Tyr Val Lys Leu Lys Leu Ile Pro Asp Pro Lys Ser Glu Ser 
        195                 200                 205


Lys Gln Lys Thr Lys Thr Ile Lys Cys Ser Leu Asn Pro Glu Trp Asn 
    210                 215                 220


Glu Thr Phe Arg Phe Gln Leu Lys Glu Ser Asp Lys Asp Arg Arg Leu 
225                 230                 235                 240


Ser Val Glu Ile Trp Asp Trp Asp Leu Thr Ser Arg Asn Asp Phe Met 
                245                 250                 255


Gly Ser Leu Ser Phe Gly Ile Ser Glu Leu Gln Lys Ala Ser Val Asp 
            260                 265                 270


Gly Trp Phe Lys Leu Leu Ser Gln Glu Glu Gly Glu Tyr Phe Asn Val 
        275                 280                 285


Pro Val Pro Pro Glu Gly Ser Glu Ala Asn Glu Glu Leu Arg Gln Lys 
    290                 295                 300


Phe Glu Arg Ala Lys Ile Ser Gln Gly Thr Lys Val Pro Glu Glu Lys 
305                 310                 315                 320


Thr Thr Asn Thr Val Ser Lys Phe Asp Asn Asn Gly Asn Arg Asp Arg 
                325                 330                 335


Met Lys Leu Thr Asp Phe Asn Phe Leu Met Val Leu Gly Lys Gly Ser 
            340                 345                 350


Phe Gly Lys Val Met Leu Ser Glu Arg Lys Gly Thr Asp Glu Leu Tyr 
        355                 360                 365


Ala Val Lys Ile Leu Lys Lys Asp Val Val Ile Gln Asp Asp Asp Val 
    370                 375                 380


Glu Cys Thr Met Val Glu Lys Arg Val Leu Ala Leu Pro Gly Lys Pro 
385                 390                 395                 400


Pro Phe Leu Thr Gln Leu His Ser Cys Phe Gln Thr Met Asp Arg Leu 
                405                 410                 415


Tyr Phe Val Met Glu Tyr Val Asn Gly Gly Asp Leu Met Tyr His Ile 
            420                 425                 430


Gln Gln Val Gly Arg Phe Lys Glu Pro His Ala Val Phe Tyr Ala Ala 
        435                 440                 445


Glu Ile Ala Ile Gly Leu Phe Phe Leu Gln Ser Lys Gly Ile Ile Tyr 
    450                 455                 460


Arg Asp Leu Lys Leu Asp Asn Val Met Leu Asp Ser Glu Gly His Ile 
465                 470                 475                 480


Lys Ile Ala Asp Phe Gly Met Cys Lys Glu Asn Ile Trp Asp Gly Val 
                485                 490                 495


Thr Thr Lys Thr Phe Cys Gly Thr Pro Asp Tyr Ile Ala Pro Glu Ile 
            500                 505                 510


Ile Ala Tyr Gln Pro Tyr Gly Lys Ser Val Asp Trp Trp Ala Phe Gly 
        515                 520                 525


Val Leu Leu Tyr Glu Met Leu Ala Gly Gln Ala Pro Phe Glu Gly Glu 
    530                 535                 540


Asp Glu Asp Glu Leu Phe Gln Ser Ile Met Glu His Asn Val Ala Tyr 
545                 550                 555                 560


Pro Lys Ser Met Ser Lys Glu Ala Val Ala Ile Cys Lys Gly Leu Met 
                565                 570                 575


Thr Lys His Pro Gly Lys Arg Leu Gly Cys Gly Pro Glu Gly Glu Arg 
            580                 585                 590


Asp Ile Lys Glu His Ala Phe Phe Arg Tyr Ile Asp Trp Glu Lys Leu 
        595                 600                 605


Glu Arg Lys Glu Ile Gln Pro Pro Tyr Lys Pro Lys Ala Arg Asp Lys 
    610                 615                 620


Arg Asp Thr Ser Asn Phe Asp Lys Glu Phe Thr Arg Gln Pro Val Glu 
625                 630                 635                 640


Leu Thr Pro Thr Asp Lys Leu Phe Ile Met Asn Leu Asp Gln Asn Glu 
                645                 650                 655


Phe Ala Gly Phe Ser Tyr Thr Asn Pro Glu Phe Val Ile Asn Val 
            660                 665                 670


<210>  8905
<211>  2296
<212>  DNA
<213>  Homo sapiens

<400>  8905
aagaataaaa gcaggctgcc tgaggttgcg gtggtaacat gtttcggcgt ccttccacac     60

tgtcgcggct tatgttgttt tgctgtttgg gtttgcactg tctttttgag ctgtaacaca    120

gcaaaggttt gcagtttcgc tcctgaaatc atcgagacca caaacccacc gggaagaacg    180

aacaactcca gacgcaccgc tttaagagct gtaatactcg ttaggaaggt gtgcagcttg    240

actcctgagt cagcgagacc atgaacccat cagaaggaaa aaactccgaa catcagaagg    300

aacaagtttc agacacgcca cctttaagaa ctgtgatact caccgcgagg gcccgcggct    360

tcattcttga agtccgtgag accaagaacc taccaattcc gaatacgttg ggttcaagtg    420

gttctcctgc ctcagactcc cgaatacctg ggactacagg cacccaccac gcccgggtaa    480

ttgtatgaca atggagaggt gattactgcg ctgaaaatca gtttcctgaa gtgaaaaagg    540

gaatcaagtt acgtcacaga gcctggtgtg agcggcgctc tgtcaacacc agctcttcat    600

gggttgtggt ttcctccagt tcctggatgt gtggagttca tcctccactg actggcgccc    660

cggttgacaa tgaggtctgg catccctgga gttgagtaac tagttctggc tgctggtctc    720

caggtgacat gtgtcacgtt tgagctaaga attgcttcac atgattatgg aggctgacaa    780

gtcccaagac tcacagtcgg caagctggac acccaagaca gctggtgctg cacatattac    840

cagtgatgta gtttcagtct gaatctgaag gcctgagaac caggacagtt gatggtgtaa    900

attccagtcc gaggtcagga gaagcctaat gttctagcct aacatcttgc agcttttttg    960

ttctatgcaa gttttaaagt aattggatgg gacccagcca cattagggag gccaatctgc   1020

tttactcagt ctaccaattc aaatctaatc ttatccagaa acaccctcgt agacacatcc   1080

acagtaatat ttgaccaaat atctcagcac tcaaaggctt aggcaagtcg atatgtaaaa   1140

ttaatgatca caaggaggga gaatgggttc aacaggtatt taaaagtatt cataatagaa   1200

aagtatttat tgtgtttatg tggcaggcag tattctgagt gctgttattg tatctcagtt   1260

aaaacactag ttaggtaaga aaagcgtcac ctctgtgagg tggttactat tattgtcctc   1320

atttagcaga tgagaaaaca ggcagagaaa aatttacatg atttgctggc actcatgcaa   1380

ctgataagta tctgaactgg gattcgaacc caaactaact cagagtttaa gctcttaact   1440

gccattctag agtcctcctt ggggacaggt gattgtaggt agaaaaaaga aatatgggga   1500

gaggcatgct gaattgaaaa aaaaaacctc tctaaatgaa actgagaacc acatcttcta   1560

gtactaatta taggtagaga actctgctaa atattttgca agcattatcc aatttaatga   1620

taaaaaccat actggacatg agaagccatt atatccattt tacagaaaag aaaaatgagc   1680

tgggttggaa ttgcagctgg gacatttttg atactgtgat cttagataca ttcatctgtc   1740

agactccagc tgattccaaa ctccttgttc attctattag gttgtgctat aagaaaaaat   1800

tctgtaagct ttaaaagtgg taagtcaact caaggcacag ccaataagca tttatatgac   1860

tgtacattat ttacctaact ctgcagaggg agccagatat cctttagtgt agtaacgaag   1920

aatggctcct gcatatcccc agcaattctc aggaaaaggt gggtgttata ttctcttaaa   1980

tagagaggcg tttttttctt agtcctatta ctggcagctt ctaaatttaa taacaaaatg   2040

ctcacctaca aataagaaga ataaaagctt aacttgccag ggggaaaaaa agttctatga   2100

tgtaacagac ccaggaataa gtgatattca tgggaaggtc actgcctgag gctgcttgat   2160

aaactccagc cctttcctat atccactgtt taatgtttaa gctttggatg ctaagagtgg   2220

ttataataaa ctgtccaaca gtttctcact tagacttccc aagaaggtga caaaataaaa   2280

tcaatgtaaa gctgtc                                                   2296


<210>  8906
<211>  75
<212>  PRT
<213>  Homo sapiens

<400>  8906

Met Asn Pro Ser Glu Gly Lys Asn Ser Glu His Gln Lys Glu Gln Val 
1               5                   10                  15


Ser Asp Thr Pro Pro Leu Arg Thr Val Ile Leu Thr Ala Arg Ala Arg 
            20                  25                  30


Gly Phe Ile Leu Glu Val Arg Glu Thr Lys Asn Leu Pro Ile Pro Asn 
        35                  40                  45


Thr Leu Gly Ser Ser Gly Ser Pro Ala Ser Asp Ser Arg Ile Pro Gly 
    50                  55                  60


Thr Thr Gly Thr His His Ala Arg Val Ile Val 
65                  70                  75


<210>  8907
<211>  558
<212>  DNA
<213>  Homo sapiens

<400>  8907
acaaagagaa gtgaccaaag aaaaaaaggc actcagcaca taacagctgt ctgaattttc     60

aaactccttt actaaggaaa aaagaaaatt aaaaatacga cttttttata aggcttttaa    120

caacgacaaa agcttgcagg ggactttgaa aatactgctg tgtttcatca aggctttttg    180

actattacag aagatgtgta ttggaagcct aatgaagtct gtttgtcttg cttccaaaac    240

tcagtatgtt ggcaggaatg actgacagga ttttgttgaa gaaaaaagat tgtcatatgg    300

tgatcaggaa caggcacaaa tctataaaac aaaataacat cctaattcca ttagatgcac    360

tattctgtag cataatgttt aattggtttc aatttaacag agattcatgt tgaactgcac    420

tctggacaat cagagatgtt gatggccata tgctgaattc ctcaaggtgc agtgagaggg    480

gcttgtgtgc ttgttaagga catggcaggc catcaacaac atatgtattg gatggcttca    540

taacacacat gctttcgg                                                  558


<210>  8908
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  8908

Met Leu Ala Gly Met Thr Asp Arg Ile Leu Leu Lys Lys Lys Asp Cys 
1               5                   10                  15


His Met Val Ile Arg Asn Arg His Lys Ser Ile Lys Gln Asn Asn Ile 
            20                  25                  30


Leu Ile Pro Leu Asp Ala Leu Phe Cys Ser Ile Met Phe Asn Trp Phe 
        35                  40                  45


Gln Phe Asn Arg Asp Ser Cys 
    50                  55


<210>  8909
<211>  6725
<212>  DNA
<213>  Homo sapiens

<400>  8909
ccacacccgg ctagtttttg tatttttagt agagaacagg gtttcaccat gttggccagg     60

ctagtctcga actcctgacc tcatgtgatc cacccacctc ggccccctca aagttctggg    120

attacaggcg cgagccacca tgcctggcca tctggataat ttttgtattt ttagtagaga    180

cggtttcagc atgttggcca ggctattctc gaattcctga cctcaagtaa tctgccctcc    240

ttggcctccc aaagtggtgg gattacaggc gtgagccact gtgtctgccc acttttaatt    300

aatgctatac atttgataag ctttcctatt aagaatttaa tgtgatcatt ttatcatcaa    360

attactttta tcatactgtc ttagaaatat ttttaaactt tgcttttatg tagaaaaggt    420

caattaccaa acagggtatt gttttatagg ctactggtgt ttcccatatg tttatgtttt    480

gtgctgtcca tgatagagag gtggtgtctg tagtcttttg agtcctgtta actataaaaa    540

gccaatagca gttggtgccg tggttccaca ccctggggtg gaggtgagag atgagttcct    600

gccatctttt ttgggatggc ccattagcct gttggcaccc atccctcaaa agatgggttt    660

aatgataaat ttggtcgcat gtaggcatct gtctgggaag gaatctgtgt accttgatac    720

tctgagagtg ttttcctggg ctaacctcag agccaatact ttacttctca ggaagtaatc    780

tgtgggatca agacaacaat ttacacgtta aaaaataaac tctacagccc actagcatca    840

acatagcttt atgcttttga cttcattcat ctgctactat gaccttttta cttttttatt    900

tatttattta tttttaccag tgtgcagtat gcctatgtaa tactataagc gttttagttt    960

ttaaaattgt aatgctttct gttgctcata tattgatcaa aaactgatca acctatgagt   1020

agtactttga ggttgtatgt gttcgatttt gtctcctcct gcagtgaatt gatttttctt   1080

gagcagattg attagatgga gctgccttga tttacacatc agtgaaagaa gagaaaaacc   1140

tcgacttgtt gtataagtat attgttcata aaacatacgg tttccacttc accacacctg   1200

ccttagttgt ggaaaaggat gccgttttta tgtgagttat tttgagctga tgctttgaaa   1260

ctcttctttt taaagtacat ttgcttttta cattttaccc cttcaaggaa ggtgccttct   1320

gtctgtgtct tctacagcca gctctctcac tgcaccttct ctctgttcct ttccggatta   1380

tgaggcatct gcctgaggga agtgggtggt gtggtcaggg gtgctgcctt tcttcctcga   1440

gagcaagttg ccaaaaccta agccagccat ttttggcact cactgtcaac tctggtaaaa   1500

tactggctgg ggagggaata tagggaattg tgcttggggg atcctgaatg tcttctatta   1560

aagcgcctgc tttatctgtg tgttggcagg gatgactgca aacatcctct cggcatctct   1620

gtcagcatgg gctttcgcta tattaagtgc ttactgtgct tctggcattt cacattttgg   1680

gagccaccgg gattgattgt cctcgataga gacttggata cctgttttcc taagctggtg   1740

tctttctctc actggagaat catagtgttg ctggatgcat aaatatgaag ctgtggtctc   1800

tgacaagact tgtgttagca gattgatgtt caggcttcag tatcctcctg acttaacaaa   1860

caattacatt attcattcag gaaaccttat tcagcaccca ctaggtgctc aggttctctg   1920

caaaggacac agaaatgaat gatacgtgtt ccttgcatat ggcactgtct agaggggaca   1980

tacacagctg aagaagggaa gggcagtgat ggggttatgg aggaagtatg gcagggaaag   2040

caggagggtg atgctggaag acaaatggta gatcccaggc ggactggaaa gaattgcaat   2100

agggggagcc ggggagtgca gtctgtgaga ggctggaaat gtgaaagcca ggagctctca   2160

gggatttggg ttgcctcctg cacagtcaag gagagtgtca ctcaggctag tcatagatgg   2220

catacctaca ggcttgggct gattttagat agttgttcag agcagtcagg caggcgccag   2280

aggcacaagc cctgtgagag gtgtgtttgg aatcacttgg tatccaaatc acatgtcatc   2340

cctaggagca aggagaccgg ttggatttgg ggctggtctg gaatgaagaa gcatctctca   2400

gcttccgaag gctgcatggc tcacggcagt atctcaatca tgccctgccc gtttgcacat   2460

ttggtcctgt tggtagttac ctctctggtg actggcaaag tcagcaagga tattggggtg   2520

gagcaccctg gctaagcacc ctcttgatta tagagctatg gagtagaaga cagatggaga   2580

atgagaggcc tgtgagaaca atcagtcagt tgccatcttt cagagctgct cgagttcaaa   2640

agtgtgtcat acagggtatt ttaccattgc tacctttaag ggattcaggt gggaacccta   2700

ggctgtggct tcacataatg gaacttgggt gccatcctac cctgtgatgt tgagctggcc   2760

agcactggtg taggaacctc aaggactctg tgcttctctg gtttggggcc taggataaac   2820

acaggccctg cttgcccctt ggttctagga cacatcttcc catgccagca aagttaatga   2880

accagtctac aagataactg ttgaaagaat tcttagagaa acaacccaca ggaggggagc   2940

catgtcagag cccaagaaaa ccatcccatc ctgagctctg ccttctgtgc tgctctctgc   3000

atcctattct ctgtcggaac aggaccccac tgtgtccttg ctcttctagg cagagttgtg   3060

ggagagtgct aaatgctttt gagtggggca gcctgtggaa tgggatctca tactggctcc   3120

ttagaccttg ggcccatgaa ctcagtatgg agcaggacct gcgatgttct gatggattat   3180

acccacagtg tattttggca catctgccaa aagctacaaa caacccccaa caactacaca   3240

ctatatcttg tgagaagtgt cctacccagg agtcctgaat gtgatctgag tatgctctaa   3300

ggcagcccca ggaaaagcaa ttcagtccct ctctctttgc ctttagacct gcaggctggg   3360

acaatgaaaa gaaaatagct attttacatg aaaattttac aaccgtgaag ccggaagatg   3420

catatgaaga ctttattgtg aaacctcccg tgagaaagct ggtccacgac aaagagttgg   3480

cagcagaaga tgagcaggtg ttcctaatga agcaacagtc actccttgcc aagcaaccag   3540

ccactcccac gagagcttct gaatctcctg caagaggacc ctctggctct ccaaggaccc   3600

agggtcgggg agggccagcc agtgtgccta gctcctcccc aggcacgtca gtaaaaaagc   3660

cggacccaaa catcaaaaat aatgcagcaa gtgaaggggt gttggccagc ttcttcaaca   3720

gtctgttgag taaaaagaca ggctctcctg gaagtcctgg tgctggtggg gtgcagagca   3780

cagccaagaa gtcaggacaa aagactgtgt tgtcaaatgt tcaggaagaa ctggatagaa   3840

tgactcgaaa gccagactct atggtaacaa actcttcaac agaaaatgaa gcctgaacct   3900

ccttaaaaag tgcatatgtc gaatgaccaa ataactatgt atattgatct gctaagacca   3960

ggatttttct gatatggcac atgctatcag ttttttgggg caggggagat gaactttaaa   4020

aaaaaaaaaa aaacttcatt ggcttgtccg agtgtgaaat gcacatttag gaaggttaca   4080

tgtcagaccc tttgttaagg ataacccttg gactctgggg catgtggctc ttttgtggga   4140

ggcaagcaca tctgggcttc ttgtggaggg gaaggtagag tgaaagaaag agggcccact   4200

ttctaacagg gtggagcaaa tgagaccaag aaatcattgg taagatgatg gttagtctga   4260

ccagtttcat gttagtaaat tcacttgttc ttgggaagca gattaagtag cagaaagtcc   4320

aggaaagaaa gaccagaagg agtaatgaga caagtgatgg tggggaagct gaatgttgag   4380

ggaggtggag gaaggaggag atgagcagtg tcagtaaata ctgtgcattc agtagaagtt   4440

gaagaatcat tgttagaagc atttccaaac aaaacactaa gcaaaatggg aattaggctt   4500

attttgaatg catctttaac ttacgaaaga tgtactaatt gtgggggtgc ctgagtcagg   4560

cggagctgac ccaggggtgg gaacgatggc agctgcccag gacccatgtg cttggcccag   4620

gctatgtcct cgtgagaggt actggggtcc acggatatgt gttgtggggc agacagtcac   4680

tgtgggatgt cttcaaagtc agcagttaca gaattagttt actttgaatt ttgttgtcta   4740

aatagctcct gctttatttt ttaaattaaa ttttttgttt ttactatcac aggctggcct   4800

aactaataca aaataggtga tgaacctctg gttttaccat aatgcaatgt gccacggaaa   4860

gtttggggga ggtttttaat gtaattgcac tctggttaat tggctcgtac caagccctgc   4920

cttatgactt gtggaaagct tcaaggagtt ccactgatgc aaaagggtct tttcctagct   4980

tcctggtctg atcagtgcta tgagatggac agataagtgt gaatgtttta tacagaaaat   5040

ggaaatgata catttctctt gttaggtgtt ttcataaaat gtagcatttt ttttcttatg   5100

gaaataagag tttcaggtgt ctccccacct agggcaaatt catgcacatt gtcatgttat   5160

accaccattc tggaaatgat ttctgtggat ttgaaattgc acttttaatt ttatatatga   5220

cagcatttaa atgcaaacac taccatgaat ttaatgtata aaatgttgtc aaaccaaggg   5280

aaaaaaccac agttcaccat gtggagttta ctttttttat atgaatgttt gttgtactgt   5340

gtctaagcat aacttcccta atgtcattac ttttacatac cagatttgac tgaccactaa   5400

tgtagtactg gggataactt aatatcctat gttgtgtcaa gactctttga agactttctt   5460

gaattgcttt cgtaaaggtc tgaacactgt taaggagaaa gctgagtatc aacttgcctt   5520

tctgatagaa atgtttcttg tgccagtttt attgttgaga tatactattt ttttcctttt   5580

ttaattcagt tttttaaaaa aacaaatgta ttgtggcttc cagttaccag gttgtctagg   5640

taatgacagt aaactgactg tagaatgata attgtggtat agtgaccaat agatgccaaa   5700

cagcttgtgg cctcactaaa ggtggggtcg cttagtcccc gggagtaaaa tgagtgacct   5760

cagaaacaag aattcctgga aaggcacatg ccgaagagga atatggtata attttaaatt   5820

ttaatgcaaa attttaattt gtctttattt tttatcattt gaactgataa gcactttttg   5880

tgtcaatata aaatatacta aaactgatga aatgctaaga catgtcttgt gaaggaaggt   5940

ttcttggaga ccacttttat ttactcatga gaagtggaag ctcctagtat cagaagaagc   6000

tgatacatag tgtcatgtgc tcagtggttg ccaaagtcta ccaactttgg ggagctgcag   6060

ggttcttttt gggaggtggg aggaagggag atgagttttg ttattttggg gttttcaagc   6120

attggaacca aaggccaaat aataaacagc ctttagtttt taaagtaaaa ttcattttat   6180

ttgcagagta cacttgtatg gtagactgtt aaagacaatt ttatgactat ttatgcacat   6240

tataatggtt acatctgctt tttgtcttta aaataaaaaa aaaaatcaga gaaaagccca   6300

cctttgaata cgtggctgaa gataacagcc aagaattggt ctttcctaaa aatgcaacag   6360

ataatgctgc tagattgtta ttttgtttgc actttttttt gattggcatt ttaaaatcgg   6420

tatttaaact gaagacattg tcatgtttta ttaatttaac aaagttgaaa gtgactgctc   6480

tgtacatcat gaccttaaca atgttaatgc tgtaagtgaa agttcactgt cgtctgtata   6540

ctaaatttat tggtgtttct aacttaaaag taagactgca gattatcccc caccagcctt   6600

agtccagggg tgtggctctg tccgggtgca gtatgcagtc atgtggaacc ttgctttcta   6660

gtcctgggaa aaaaagatgt ctctaattac tggcttcaat aaacacgaat ccagactgct   6720

tacaa                                                               6725


<210>  8910
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  8910

Met Lys Gln Gln Ser Leu Leu Ala Lys Gln Pro Ala Thr Pro Thr Arg 
1               5                   10                  15


Ala Ser Glu Ser Pro Ala Arg Gly Pro Ser Gly Ser Pro Arg Thr Gln 
            20                  25                  30


Gly Arg Gly Gly Pro Ala Ser Val Pro Ser Ser Ser Pro Gly Thr Ser 
        35                  40                  45


Val Lys Lys Pro Asp Pro Asn Ile Lys Asn Asn Ala Ala Ser Glu Gly 
    50                  55                  60


Val Leu Ala Ser Phe Phe Asn Ser Leu Leu Ser Lys Lys Thr Gly Ser 
65                  70                  75                  80


Pro Gly Ser Pro Gly Ala Gly Gly Val Gln Ser Thr Ala Lys Lys Ser 
                85                  90                  95


Gly Gln Lys Thr Val Leu Ser Asn Val Gln Glu Glu Leu Asp Arg Met 
            100                 105                 110


Thr Arg Lys Pro Asp Ser Met Val Thr Asn Ser Ser Thr Glu Asn Glu 
        115                 120                 125


Ala 



<210>  8911
<211>  4539
<212>  DNA
<213>  Homo sapiens

<400>  8911
ggctgccccg gcggctgcct gaccgccgcc cgccacctcg gcggcctcgc aacccgtggg     60

agcccgtggc catcgcagac ctagaggaca cgttgggcgg cgcagtcgcc gcggcaaggt    120

cggcgggcgg cgcggcgcga gggacggcga gcggggggcg gcccggcccg ggtcctcgcg    180

ggtcctcggc gggcccgggg gagggccctc tttgtggctg cagttggcaa gatggcgccg    240

gtgggggtgg agaagaagct gctgctaggt cccaacgggc ccgcggtggc ggccgccggc    300

gacctgacca gtgaggagga ggaaggccag agcctatggt cctccattct gagcgaagtg    360

tccacccgcg ccaggtccaa gctgccgtcc ggcaagaaca tcctggtctt cggtgaagat    420

ggttctggta aaacaaccct catgactaaa ctacaaggag ctgagcatgg caaaaaagga    480

agaggcctag aatatctcta cctcagtgtc catgatgagg accgagatga tcacacgcgc    540

tgcaacgtgt ggattctgga tggagacttg taccacaaag gcctgctgaa atttgcagtt    600

tctgctgaat ccttgccaga gaccctcgtc atttttgttg cagacatgtc tagaccttgg    660

actgtgatgg aatctctgca gaaatgggct agtgttttac gtgagcacat tgataaaatg    720

aaaattccac cagaaaaaat gagggagctg gaacggaagt ttgtgaaaga ttttcaagac    780

tatatggaac ctgaagaagg ttgtcaaggt tccccacaga gaagaggccc tctgacctca    840

ggctccgatg aagaaaatgt tgccctgcct ctgggtgaca atgtgctgac tcataacctg    900

gggatcccgg tgttggtggt gtgcacaaag tgtgatgcgg tgagtgtcct ggagaaggag    960

cacgattaca gggatgagca tttggacttt atccagtcac acctgcggag gttctgcctt   1020

cagtatggag ctgccttgat ttacacatca gtgaaagaag agaaaaacct cgacttgttg   1080

tataagtata ttgttcataa aacatacggt ttccacttca ccacacctgc cttagttgtg   1140

gaaaaggatg ccgtttttat acctgcaggc tgggacaatg aaaagaaaat agctatttta   1200

catgaaaatt ttacaaccgt gaagccggaa gatgcatatg aagactttat tgtgaaacct   1260

cccgtgagaa agctggtcca cgacaaagag ttggcagcag aagatgagca ggtgttccta   1320

atgaagcaac agtcactcct tgccaagcaa ccagccactc ccacgagagc ttctgaatct   1380

cctgcaagag gaccctctgg ctctccaagg acccagggtc ggggagggcc agccagtgtg   1440

cctagctcct ccccaggcac gtcagtaaaa aagccggacc caaacatcaa aaataatgca   1500

gcaagtgaag gggtgttggc cagcttcttc aacagtctgt tgagtaaaaa gacaggctct   1560

cctggaagtc ctggtgctgg tggggtgcag agcacagcca agaagtcagg acaaaagact   1620

gtgttgtcaa atgttcagga agaactggat agaatgactc gaaagccaga ctctatggta   1680

acaaactctt caacagaaaa tgaagcctga acctccttaa aaagtgcata tgtcgaatga   1740

ccaaataact atgtatattg atctgctaag accaggattt ttctgatatg gcacatgcta   1800

tcagtttttt ggggcagggg agatgaactt taaaaaaaaa aaaaaaactt cattggcttg   1860

tccgagtgtg aaatgcacat ttaggaaggt tacatgtcag accctttgtt aaggataacc   1920

cttggactct ggggcatgtg gctcttttgt gggaggcaag cacatctggg cttcttgtgg   1980

aggggaaggt agagtgaaag aaagagggcc cactttctaa cagggtggag caaatgagac   2040

caagaaatca ttggtaagat gatggttagt ctgaccagtt tcatgttagt aaattcactt   2100

gttcttggga agcagattaa gtagcagaaa gtccaggaaa gaaagaccag aaggagtaat   2160

gagacaagtg atggtgggga agctgaatgt tgagggaggt ggaggaagga ggagatgagc   2220

agtgtcagta aatactgtgc attcagtaga agttgaagaa tcattgttag aagcatttcc   2280

aaacaaaaca ctaagcaaaa tgggaattag gcttattttg aatgcatctt taacttacga   2340

aagatgtact aattgtgggg gtgcctgagt caggcggagc tgacccaggg gtgggaacga   2400

tggcagctgc ccaggaccca tgtgcttggc ccaggctatg tcctcgtgag aggtactggg   2460

gtccacggat atgtgttgtg gggcagacag tcactgtggg atgtcttcaa agtcagcagt   2520

tacagaatta gtttactttg aattttgttg tctaaatagc tcctgcttta ttttttaaat   2580

taaatttttt gtttttacta tcacaggctg gcctaactaa tacaaaatag gtgatgaacc   2640

tctggtttta ccataatgca atgtgccacg gaaagtttgg gggaggtttt taatgtaatt   2700

gcactctggt taattggctc gtaccaagcc ctgccttatg acttgtggaa agcttcaagg   2760

agttccactg atgcaaaagg gtcttttcct agcttcctgg tctgatcagt gctatgagat   2820

ggacagataa gtgtgaatgt tttatacaga aaatggaaat gatacatttc tcttgttagg   2880

tgttttcata aaatgtagca ttttttttct tatggaaata agagtttcag gtgtctcccc   2940

acctagggca aattcatgca cattgtcatg ttataccacc attctggaaa tgatttctgt   3000

ggatttgaaa ttgcactttt aattttatat atgacagcat ttaaatgcaa acactaccat   3060

gaatttaatg tataaaatgt tgtcaaacca agggaaaaaa ccacagttca ccatgtggag   3120

tttacttttt ttatatgaat gtttgttgta ctgtgtctaa gcataacttc cctaatgtca   3180

ttacttttac ataccagatt tgactgacca ctaatgtagt actggggata acttaatatc   3240

ctatgttgtg tcaagactct ttgaagactt tcttgaattg ctttcgtaaa ggtctgaaca   3300

ctgttaagga gaaagctgag tatcaacttg cctttctgat agaaatgttt cttgtgccag   3360

ttttattgtt gagatatact atttttttcc ttttttaatt cagtttttta aaaaaacaaa   3420

tgtattgtgg cttccagtta ccaggttgtc taggtaatga cagtaaactg actgtagaat   3480

gataattgtg gtatagtgac caatagatgc caaacagctt gtggcctcac taaaggtggg   3540

gtcgcttagt ccccgggagt aaaatgagtg acctcagaaa caagaattcc tggaaaggca   3600

catgccgaag aggaatatgg tataatttta aattttaatg caaaatttta atttgtcttt   3660

attttttatc atttgaactg ataagcactt tttgtgtcaa tataaaatat actaaaactg   3720

atgaaatgct aagacatgtc ttgtgaagga aggtttcttg gagaccactt ttatttactc   3780

atgagaagtg gaagctccta gtatcagaag aagctgatac atagtgtcat gtgctcagtg   3840

gttgccaaag tctaccaact ttggggagct gcagggttct ttttgggagg tgggaggaag   3900

ggagatgagt tttgttattt tggggttttc aagcattgga accaaaggcc aaataataaa   3960

cagcctttag tttttaaagt aaaattcatt ttatttgcag agtacacttg tatggtagac   4020

tgttaaagac aattttatga ctatttatgc acattataat ggttacatct gctttttgtc   4080

tttaaaataa aaaaaaaaat cagagaaaag cccacctttg aatacgtggc tgaagataac   4140

agccaagaat tggtctttcc taaaaatgca acagataatg ctgctagatt gttattttgt   4200

ttgcactttt ttttgattgg cattttaaaa tcggtattta aactgaagac attgtcatgt   4260

tttattaatt taacaaagtt gaaagtgact gctctgtaca tcatgacctt aacaatgtta   4320

atgctgtaag tgaaagttca ctgtcgtctg tatactaaat ttattggtgt ttctaactta   4380

aaagtaagac tgcagattat cccccaccag ccttagtcca ggggtgtggc tctgtccggg   4440

tgcagtatgc agtcatgtgg aaccttgctt tctagtcctg ggaaaaaaag atgtctctaa   4500

ttactggctt caataaacac gaatccagac tgcttacaa                          4539


<210>  8912
<211>  492
<212>  PRT
<213>  Homo sapiens

<400>  8912

Met Ala Pro Val Gly Val Glu Lys Lys Leu Leu Leu Gly Pro Asn Gly 
1               5                   10                  15


Pro Ala Val Ala Ala Ala Gly Asp Leu Thr Ser Glu Glu Glu Glu Gly 
            20                  25                  30


Gln Ser Leu Trp Ser Ser Ile Leu Ser Glu Val Ser Thr Arg Ala Arg 
        35                  40                  45


Ser Lys Leu Pro Ser Gly Lys Asn Ile Leu Val Phe Gly Glu Asp Gly 
    50                  55                  60


Ser Gly Lys Thr Thr Leu Met Thr Lys Leu Gln Gly Ala Glu His Gly 
65                  70                  75                  80


Lys Lys Gly Arg Gly Leu Glu Tyr Leu Tyr Leu Ser Val His Asp Glu 
                85                  90                  95


Asp Arg Asp Asp His Thr Arg Cys Asn Val Trp Ile Leu Asp Gly Asp 
            100                 105                 110


Leu Tyr His Lys Gly Leu Leu Lys Phe Ala Val Ser Ala Glu Ser Leu 
        115                 120                 125


Pro Glu Thr Leu Val Ile Phe Val Ala Asp Met Ser Arg Pro Trp Thr 
    130                 135                 140


Val Met Glu Ser Leu Gln Lys Trp Ala Ser Val Leu Arg Glu His Ile 
145                 150                 155                 160


Asp Lys Met Lys Ile Pro Pro Glu Lys Met Arg Glu Leu Glu Arg Lys 
                165                 170                 175


Phe Val Lys Asp Phe Gln Asp Tyr Met Glu Pro Glu Glu Gly Cys Gln 
            180                 185                 190


Gly Ser Pro Gln Arg Arg Gly Pro Leu Thr Ser Gly Ser Asp Glu Glu 
        195                 200                 205


Asn Val Ala Leu Pro Leu Gly Asp Asn Val Leu Thr His Asn Leu Gly 
    210                 215                 220


Ile Pro Val Leu Val Val Cys Thr Lys Cys Asp Ala Val Ser Val Leu 
225                 230                 235                 240


Glu Lys Glu His Asp Tyr Arg Asp Glu His Leu Asp Phe Ile Gln Ser 
                245                 250                 255


His Leu Arg Arg Phe Cys Leu Gln Tyr Gly Ala Ala Leu Ile Tyr Thr 
            260                 265                 270


Ser Val Lys Glu Glu Lys Asn Leu Asp Leu Leu Tyr Lys Tyr Ile Val 
        275                 280                 285


His Lys Thr Tyr Gly Phe His Phe Thr Thr Pro Ala Leu Val Val Glu 
    290                 295                 300


Lys Asp Ala Val Phe Ile Pro Ala Gly Trp Asp Asn Glu Lys Lys Ile 
305                 310                 315                 320


Ala Ile Leu His Glu Asn Phe Thr Thr Val Lys Pro Glu Asp Ala Tyr 
                325                 330                 335


Glu Asp Phe Ile Val Lys Pro Pro Val Arg Lys Leu Val His Asp Lys 
            340                 345                 350


Glu Leu Ala Ala Glu Asp Glu Gln Val Phe Leu Met Lys Gln Gln Ser 
        355                 360                 365


Leu Leu Ala Lys Gln Pro Ala Thr Pro Thr Arg Ala Ser Glu Ser Pro 
    370                 375                 380


Ala Arg Gly Pro Ser Gly Ser Pro Arg Thr Gln Gly Arg Gly Gly Pro 
385                 390                 395                 400


Ala Ser Val Pro Ser Ser Ser Pro Gly Thr Ser Val Lys Lys Pro Asp 
                405                 410                 415


Pro Asn Ile Lys Asn Asn Ala Ala Ser Glu Gly Val Leu Ala Ser Phe 
            420                 425                 430


Phe Asn Ser Leu Leu Ser Lys Lys Thr Gly Ser Pro Gly Ser Pro Gly 
        435                 440                 445


Ala Gly Gly Val Gln Ser Thr Ala Lys Lys Ser Gly Gln Lys Thr Val 
    450                 455                 460


Leu Ser Asn Val Gln Glu Glu Leu Asp Arg Met Thr Arg Lys Pro Asp 
465                 470                 475                 480


Ser Met Val Thr Asn Ser Ser Thr Glu Asn Glu Ala 
                485                 490


<210>  8913
<211>  2975
<212>  DNA
<213>  Homo sapiens

<400>  8913
ggctgccccg gcggctgcct gaccgccgcc cgccacctcg gcggcctcgc aacccgtggg     60

agcccgtggc catcgcagac ctagaggaca cgttgggcgg cgcagtcgcc gcggcaaggt    120

cggcgggcgg cgcggcgcga gggacggcga gcggggggcg gcccggcccg ggtcctcgcg    180

ggtcctcggc gggcccgggg gagggccctc tttgtggctg cagttggcaa gatggcgccg    240

gtgggggtgg agaagaagct gctgctaggt cccaacgggc ccgcggtggc ggccgccggc    300

gacctgacca gtgaggagga ggaaggccag agcctatggt cctccattct gagcgaagtg    360

tccacccgcg ccaggtccaa gctgccgtcc ggcaagcaca tctgggcttc ttgtggaggg    420

gaaggtagag tgaaagaaag agggcccact ttctaacagg gtggagcaaa tgagaccaag    480

aaatcattgg taagatgatg gttagtctga ccagtttcat gttagtaaat tcacttgttc    540

ttgggaagca gattaagtag cagaaagtcc aggaaagaaa gaccagaagg agtaatgaga    600

caagtgatgg tggggaagct gaatgttgag ggaggtggag gaaggaggag atgagcagtg    660

tcagtaaata ctgtgcattc agtagaagtt gaagaatcat tgttagaagc atttccaaac    720

aaaacactaa gcaaaatggg aattaggctt attttgaatg catctttaac ttacgaaaga    780

tgtactaatt gtgggggtgc ctgagtcagg cggagctgac ccaggggtgg gaacgatggc    840

agctgcccag gacccatgtg cttggcccag gctatgtcct cgtgagaggt actggggtcc    900

acggatatgt gttgtggggc agacagtcac tgtgggatgt cttcaaagtc agcagttaca    960

gaattagttt actttgaatt ttgttgtcta aatagctcct gctttatttt ttaaattaaa   1020

ttttttgttt ttactatcac aggctggcct aactaataca aaataggtga tgaacctctg   1080

gttttaccat aatgcaatgt gccacggaaa gtttggggga ggtttttaat gtaattgcac   1140

tctggttaat tggctcgtac caagccctgc cttatgactt gtggaaagct tcaaggagtt   1200

ccactgatgc aaaagggtct tttcctagct tcctggtctg atcagtgcta tgagatggac   1260

agataagtgt gaatgtttta tacagaaaat ggaaatgata catttctctt gttaggtgtt   1320

ttcataaaat gtagcatttt ttttcttatg gaaataagag tttcaggtgt ctccccacct   1380

agggcaaatt catgcacatt gtcatgttat accaccattc tggaaatgat ttctgtggat   1440

ttgaaattgc acttttaatt ttatatatga cagcatttaa atgcaaacac taccatgaat   1500

ttaatgtata aaatgttgtc aaaccaaggg aaaaaaccac agttcaccat gtggagttta   1560

ctttttttat atgaatgttt gttgtactgt gtctaagcat aacttcccta atgtcattac   1620

ttttacatac cagatttgac tgaccactaa tgtagtactg gggataactt aatatcctat   1680

gttgtgtcaa gactctttga agactttctt gaattgcttt cgtaaaggtc tgaacactgt   1740

taaggagaaa gctgagtatc aacttgcctt tctgatagaa atgtttcttg tgccagtttt   1800

attgttgaga tatactattt ttttcctttt ttaattcagt tttttaaaaa aacaaatgta   1860

ttgtggcttc cagttaccag gttgtctagg taatgacagt aaactgactg tagaatgata   1920

attgtggtat agtgaccaat agatgccaaa cagcttgtgg cctcactaaa ggtggggtcg   1980

cttagtcccc gggagtaaaa tgagtgacct cagaaacaag aattcctgga aaggcacatg   2040

ccgaagagga atatggtata attttaaatt ttaatgcaaa attttaattt gtctttattt   2100

tttatcattt gaactgataa gcactttttg tgtcaatata aaatatacta aaactgatga   2160

aatgctaaga catgtcttgt gaaggaaggt ttcttggaga ccacttttat ttactcatga   2220

gaagtggaag ctcctagtat cagaagaagc tgatacatag tgtcatgtgc tcagtggttg   2280

ccaaagtcta ccaactttgg ggagctgcag ggttcttttt gggaggtggg aggaagggag   2340

atgagttttg ttattttggg gttttcaagc attggaacca aaggccaaat aataaacagc   2400

ctttagtttt taaagtaaaa ttcattttat ttgcagagta cacttgtatg gtagactgtt   2460

aaagacaatt ttatgactat ttatgcacat tataatggtt acatctgctt tttgtcttta   2520

aaataaaaaa aaaaatcaga gaaaagccca cctttgaata cgtggctgaa gataacagcc   2580

aagaattggt ctttcctaaa aatgcaacag ataatgctgc tagattgtta ttttgtttgc   2640

actttttttt gattggcatt ttaaaatcgg tatttaaact gaagacattg tcatgtttta   2700

ttaatttaac aaagttgaaa gtgactgctc tgtacatcat gaccttaaca atgttaatgc   2760

tgtaagtgaa agttcactgt cgtctgtata ctaaatttat tggtgtttct aacttaaaag   2820

taagactgca gattatcccc caccagcctt agtccagggg tgtggctctg tccgggtgca   2880

gtatgcagtc atgtggaacc ttgctttcta gtcctgggaa aaaaagatgt ctctaattac   2940

tggcttcaat aaacacgaat ccagactgct tacaa                              2975


<210>  8914
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  8914

Met Ala Pro Val Gly Val Glu Lys Lys Leu Leu Leu Gly Pro Asn Gly 
1               5                   10                  15


Pro Ala Val Ala Ala Ala Gly Asp Leu Thr Ser Glu Glu Glu Glu Gly 
            20                  25                  30


Gln Ser Leu Trp Ser Ser Ile Leu Ser Glu Val Ser Thr Arg Ala Arg 
        35                  40                  45


Ser Lys Leu Pro Ser Gly Lys His Ile Trp Ala Ser Cys Gly Gly Glu 
    50                  55                  60


Gly Arg Val Lys Glu Arg Gly Pro Thr Phe 
65                  70


<210>  8915
<211>  3343
<212>  DNA
<213>  Homo sapiens

<400>  8915
ggctgccccg gcggctgcct gaccgccgcc cgccacctcg gcggcctcgc aacccgtggg     60

agcccgtggc catcgcagac ctagaggaca cgttgggcgg cgcagtcgcc gcggcaaggt    120

cggcgggcgg cgcggcgcga gggacggcga gcggggggcg gcccggcccg ggtcctcgcg    180

ggtcctcggc gggcccgggg gagggccctc tttgtggctg cagttggcaa gatggcgccg    240

gtgggggtgg agaagaagct gctgctaggt cccaacgggc ccgcggtggc ggccgccggc    300

gacctgacca gtgaggagga ggaaggccag agcctatggt cctccattct gagcgaagtg    360

tccacccgcg ccaggtccaa gctgccgtcc ggcaagaaca tcctggtctt cggtgaagat    420

ggttctggta aaacaaccct catgactaaa ctacaaggag ctgagcatgg caaaaaagga    480

agaggcctag aatatctcta cctcagtgtc catgatgagg accgagatga tcacacgcgc    540

tgcaacgtgt ggattctgga tggagacttg taccacaaag gcctgctgaa atttgcagtt    600

tctgctgaat ccttgccaga gaccctcgtc atttttgttg cagacatgtc tagaccttgg    660

actgtgatgg aatctctgca gaaatgggct agtgttttac gtgagcacat tgataaaatg    720

aaaattccac cagaaaaaat gagggagctg gaacggaagt ttgtgaaaga ttttcaagac    780

tatatggaac ctgaagaagg ttgtcaaggt tccccacttt ctaacagggt ggagcaaatg    840

agaccaagaa atcattggta agatgatggt tagtctgacc agtttcatgt tagtaaattc    900

acttgttctt gggaagcaga ttaagtagca gaaagtccag gaaagaaaga ccagaaggag    960

taatgagaca agtgatggtg gggaagctga atgttgaggg aggtggagga aggaggagat   1020

gagcagtgtc agtaaatact gtgcattcag tagaagttga agaatcattg ttagaagcat   1080

ttccaaacaa aacactaagc aaaatgggaa ttaggcttat tttgaatgca tctttaactt   1140

acgaaagatg tactaattgt gggggtgcct gagtcaggcg gagctgaccc aggggtggga   1200

acgatggcag ctgcccagga cccatgtgct tggcccaggc tatgtcctcg tgagaggtac   1260

tggggtccac ggatatgtgt tgtggggcag acagtcactg tgggatgtct tcaaagtcag   1320

cagttacaga attagtttac tttgaatttt gttgtctaaa tagctcctgc tttatttttt   1380

aaattaaatt ttttgttttt actatcacag gctggcctaa ctaatacaaa ataggtgatg   1440

aacctctggt tttaccataa tgcaatgtgc cacggaaagt ttgggggagg tttttaatgt   1500

aattgcactc tggttaattg gctcgtacca agccctgcct tatgacttgt ggaaagcttc   1560

aaggagttcc actgatgcaa aagggtcttt tcctagcttc ctggtctgat cagtgctatg   1620

agatggacag ataagtgtga atgttttata cagaaaatgg aaatgataca tttctcttgt   1680

taggtgtttt cataaaatgt agcatttttt ttcttatgga aataagagtt tcaggtgtct   1740

ccccacctag ggcaaattca tgcacattgt catgttatac caccattctg gaaatgattt   1800

ctgtggattt gaaattgcac ttttaatttt atatatgaca gcatttaaat gcaaacacta   1860

ccatgaattt aatgtataaa atgttgtcaa accaagggaa aaaaccacag ttcaccatgt   1920

ggagtttact ttttttatat gaatgtttgt tgtactgtgt ctaagcataa cttccctaat   1980

gtcattactt ttacatacca gatttgactg accactaatg tagtactggg gataacttaa   2040

tatcctatgt tgtgtcaaga ctctttgaag actttcttga attgctttcg taaaggtctg   2100

aacactgtta aggagaaagc tgagtatcaa cttgcctttc tgatagaaat gtttcttgtg   2160

ccagttttat tgttgagata tactattttt ttcctttttt aattcagttt tttaaaaaaa   2220

caaatgtatt gtggcttcca gttaccaggt tgtctaggta atgacagtaa actgactgta   2280

gaatgataat tgtggtatag tgaccaatag atgccaaaca gcttgtggcc tcactaaagg   2340

tggggtcgct tagtccccgg gagtaaaatg agtgacctca gaaacaagaa ttcctggaaa   2400

ggcacatgcc gaagaggaat atggtataat tttaaatttt aatgcaaaat tttaatttgt   2460

ctttattttt tatcatttga actgataagc actttttgtg tcaatataaa atatactaaa   2520

actgatgaaa tgctaagaca tgtcttgtga aggaaggttt cttggagacc acttttattt   2580

actcatgaga agtggaagct cctagtatca gaagaagctg atacatagtg tcatgtgctc   2640

agtggttgcc aaagtctacc aactttgggg agctgcaggg ttctttttgg gaggtgggag   2700

gaagggagat gagttttgtt attttggggt tttcaagcat tggaaccaaa ggccaaataa   2760

taaacagcct ttagttttta aagtaaaatt cattttattt gcagagtaca cttgtatggt   2820

agactgttaa agacaatttt atgactattt atgcacatta taatggttac atctgctttt   2880

tgtctttaaa ataaaaaaaa aaatcagaga aaagcccacc tttgaatacg tggctgaaga   2940

taacagccaa gaattggtct ttcctaaaaa tgcaacagat aatgctgcta gattgttatt   3000

ttgtttgcac ttttttttga ttggcatttt aaaatcggta tttaaactga agacattgtc   3060

atgttttatt aatttaacaa agttgaaagt gactgctctg tacatcatga ccttaacaat   3120

gttaatgctg taagtgaaag ttcactgtcg tctgtatact aaatttattg gtgtttctaa   3180

cttaaaagta agactgcaga ttatccccca ccagccttag tccaggggtg tggctctgtc   3240

cgggtgcagt atgcagtcat gtggaacctt gctttctagt cctgggaaaa aaagatgtct   3300

ctaattactg gcttcaataa acacgaatcc agactgctta caa                     3343


<210>  8916
<211>  209
<212>  PRT
<213>  Homo sapiens

<400>  8916

Met Ala Pro Val Gly Val Glu Lys Lys Leu Leu Leu Gly Pro Asn Gly 
1               5                   10                  15


Pro Ala Val Ala Ala Ala Gly Asp Leu Thr Ser Glu Glu Glu Glu Gly 
            20                  25                  30


Gln Ser Leu Trp Ser Ser Ile Leu Ser Glu Val Ser Thr Arg Ala Arg 
        35                  40                  45


Ser Lys Leu Pro Ser Gly Lys Asn Ile Leu Val Phe Gly Glu Asp Gly 
    50                  55                  60


Ser Gly Lys Thr Thr Leu Met Thr Lys Leu Gln Gly Ala Glu His Gly 
65                  70                  75                  80


Lys Lys Gly Arg Gly Leu Glu Tyr Leu Tyr Leu Ser Val His Asp Glu 
                85                  90                  95


Asp Arg Asp Asp His Thr Arg Cys Asn Val Trp Ile Leu Asp Gly Asp 
            100                 105                 110


Leu Tyr His Lys Gly Leu Leu Lys Phe Ala Val Ser Ala Glu Ser Leu 
        115                 120                 125


Pro Glu Thr Leu Val Ile Phe Val Ala Asp Met Ser Arg Pro Trp Thr 
    130                 135                 140


Val Met Glu Ser Leu Gln Lys Trp Ala Ser Val Leu Arg Glu His Ile 
145                 150                 155                 160


Asp Lys Met Lys Ile Pro Pro Glu Lys Met Arg Glu Leu Glu Arg Lys 
                165                 170                 175


Phe Val Lys Asp Phe Gln Asp Tyr Met Glu Pro Glu Glu Gly Cys Gln 
            180                 185                 190


Gly Ser Pro Leu Ser Asn Arg Val Glu Gln Met Arg Pro Arg Asn His 
        195                 200                 205


Trp 



<210>  8917
<211>  1488
<212>  DNA
<213>  Homo sapiens

<400>  8917
ggctgccccg gcggctgcct gaccgccgcc cgccacctcg gcggcctcgc aacccgtggg     60

agcccgtggc catcgcagac ctagaggaca cgttgggcgg cgcagtcgcc gcggcaaggt    120

cggcgggcgg cgcggcgcga gggacggcga gcggggggcg gcccggcccg ggtcctcgcg    180

ggtcctcggc gggcccgggg gagggccctc tttgtggctg cagttggcaa gatggcgccg    240

gtgggggtgg agaagaagct gctgctaggt cccaacgggc ccgcggtggc ggccgccggc    300

gacctgacca gtgaggagga ggaaggccag agcctatggt cctccattct gagcgaagtg    360

tccacccgcg ccaggtccaa gctgccgtcc ggcaagaaca tcctggtctt cggtgaagat    420

ggttctggta aaacaaccct catgactaaa ctacaaggag ctgagcatgg caaaaaagga    480

agaggcctag aatatctcta cctcagtgtc catgatgagg accgagatga tcacacgcgc    540

tgcaacgtgt ggattctgga tggagacttg taccacaaag gcctgctgaa atttgcagtt    600

tctgctgaat ccttgccaga gaccctcgtc atttttgttg cagacatgtc tagaccttgg    660

actgtgatgg aatctctgca gaaatgggct agtgttttac gtgagcacat tgataaaatg    720

aaaattccac cagaaaaaat gagggagctg gaacggaagt ttgtgaaaga ttttcaagac    780

tatatggaac ctgaagaagg ttgtcaaggt tccccacaga gaagaggccc tctgacctca    840

ggctccgatg aagaaaatgt tgccctgcct ctgggtgaca atgtgctgac tcataacctg    900

gggatcccgg tgttggtggt gtgcacaaag tgtgatgcgg tgagtgtcct ggagaaggag    960

cacgattaca gggatgagca tttggacttt atccagtcac acctgcggag gttctgcctt   1020

cagtatggag ctgccttgat ttacacatca gtgaaagaag agaaaaacct cgacttgttg   1080

tataagtata ttgttcataa aacatacggt ttccacttca ccacacctgc cttagttgtg   1140

gaaaaggatg ccgtttttat acctgcaggc tgggacaatg aaaagaaaat agctatttta   1200

catgaaaatt ttacaaccgt gaagccggaa gatgcatatg aagactttat tgtgaaacct   1260

cccgtgagaa agctggtcca cgacaaagag ttggcagcag aagatgagca ggtgttccta   1320

atgaagcaac agtcactcct tgccaagcaa ccagccactc ccacgagagc ttctgaatct   1380

cctgcaagag gaccctctgg ctctccaagg acccagggtc ggggagggcc agccagtgtg   1440

cctagctcct ccccaggcac gtcagtaaaa aagccggacc caaacatc                1488


<210>  8918
<211>  418
<212>  PRT
<213>  Homo sapiens

<400>  8918

Met Ala Pro Val Gly Val Glu Lys Lys Leu Leu Leu Gly Pro Asn Gly 
1               5                   10                  15


Pro Ala Val Ala Ala Ala Gly Asp Leu Thr Ser Glu Glu Glu Glu Gly 
            20                  25                  30


Gln Ser Leu Trp Ser Ser Ile Leu Ser Glu Val Ser Thr Arg Ala Arg 
        35                  40                  45


Ser Lys Leu Pro Ser Gly Lys Asn Ile Leu Val Phe Gly Glu Asp Gly 
    50                  55                  60


Ser Gly Lys Thr Thr Leu Met Thr Lys Leu Gln Gly Ala Glu His Gly 
65                  70                  75                  80


Lys Lys Gly Arg Gly Leu Glu Tyr Leu Tyr Leu Ser Val His Asp Glu 
                85                  90                  95


Asp Arg Asp Asp His Thr Arg Cys Asn Val Trp Ile Leu Asp Gly Asp 
            100                 105                 110


Leu Tyr His Lys Gly Leu Leu Lys Phe Ala Val Ser Ala Glu Ser Leu 
        115                 120                 125


Pro Glu Thr Leu Val Ile Phe Val Ala Asp Met Ser Arg Pro Trp Thr 
    130                 135                 140


Val Met Glu Ser Leu Gln Lys Trp Ala Ser Val Leu Arg Glu His Ile 
145                 150                 155                 160


Asp Lys Met Lys Ile Pro Pro Glu Lys Met Arg Glu Leu Glu Arg Lys 
                165                 170                 175


Phe Val Lys Asp Phe Gln Asp Tyr Met Glu Pro Glu Glu Gly Cys Gln 
            180                 185                 190


Gly Ser Pro Gln Arg Arg Gly Pro Leu Thr Ser Gly Ser Asp Glu Glu 
        195                 200                 205


Asn Val Ala Leu Pro Leu Gly Asp Asn Val Leu Thr His Asn Leu Gly 
    210                 215                 220


Ile Pro Val Leu Val Val Cys Thr Lys Cys Asp Ala Val Ser Val Leu 
225                 230                 235                 240


Glu Lys Glu His Asp Tyr Arg Asp Glu His Leu Asp Phe Ile Gln Ser 
                245                 250                 255


His Leu Arg Arg Phe Cys Leu Gln Tyr Gly Ala Ala Leu Ile Tyr Thr 
            260                 265                 270


Ser Val Lys Glu Glu Lys Asn Leu Asp Leu Leu Tyr Lys Tyr Ile Val 
        275                 280                 285


His Lys Thr Tyr Gly Phe His Phe Thr Thr Pro Ala Leu Val Val Glu 
    290                 295                 300


Lys Asp Ala Val Phe Ile Pro Ala Gly Trp Asp Asn Glu Lys Lys Ile 
305                 310                 315                 320


Ala Ile Leu His Glu Asn Phe Thr Thr Val Lys Pro Glu Asp Ala Tyr 
                325                 330                 335


Glu Asp Phe Ile Val Lys Pro Pro Val Arg Lys Leu Val His Asp Lys 
            340                 345                 350


Glu Leu Ala Ala Glu Asp Glu Gln Val Phe Leu Met Lys Gln Gln Ser 
        355                 360                 365


Leu Leu Ala Lys Gln Pro Ala Thr Pro Thr Arg Ala Ser Glu Ser Pro 
    370                 375                 380


Ala Arg Gly Pro Ser Gly Ser Pro Arg Thr Gln Gly Arg Gly Gly Pro 
385                 390                 395                 400


Ala Ser Val Pro Ser Ser Ser Pro Gly Thr Ser Val Lys Lys Pro Asp 
                405                 410                 415


Pro Asn 



<210>  8919
<211>  1325
<212>  DNA
<213>  Homo sapiens

<400>  8919
atcactgaat tctgatgggc tacctggaac tggcttaggg tgggattaca tacgcctcct     60

gccacatcgg atttccttct attttgtcag gggtggcatc atccagtgag taaatctgtt    120

agtgatctcc ctcgcataac ctaggaattc tctcaggatc catttttcca gtagttttga    180

gaaagcgacc aacaacagca aagagagtag ttcttccatt ccaagagcag ccatcttgct    240

taactgacaa actagagaga actgcaagga ctcagtacat ccctggcaca gtccattctc    300

tctcacagca tattgtatga gactgtgtga gtgctgcttc cacgctacac taaaaaccca    360

tggtccctgc attatttgag caactgacaa gcttctgaag ttcaggttcg cgaacgctga    420

gagcagcacc cagtggattt gtggcaggga cagcgtttca ctatgttgtc caggcttgtt    480

tcaaactcct gggctcaagc catcagcctg cctcaacctc ctaaagtgct gacattacag    540

gcatgagcca ctgtgcccag ccaggaaatg tttcaaatac ttgagatttt tgatgaacca    600

agctggctgg tgtcgcctca gtttgtctaa attaccaagg accgctggaa tttccctggg    660

aatatgtttc gggaaaggtc agaaactctt cagtcgtctt cacgcttcca ctcagtagca    720

acgtttttgc acactcattg actatcaact ggttgtctat gactcaaatt acataatgaa    780

tccagcacat aaattattta ctcagattta atgccagcaa ctgttatctt tgtatttttt    840

tcccctctgc cagctaatct ggctcatttc attggaattt tggtcatgcc cattctcctt    900

ctgcactaaa ttaactccat aacgtagtat aaacagaaca agcttgtgtg tgatatgctt    960

aactgttaat ttacctaatt aaactaattc aattaaatca tttacatctt tttggtaaca   1020

tgccagttga taccacagca gaagtgggat gtttcagaag atgattgttc agcaaatgaa   1080

tggaaaaaaa aataaaagga aaacaaaatg agacaaccgt ccaaatctct tggcttgaaa   1140

attaaatgat actgaaaaaa tgcagctttc acggggcact gtgattagat atttttctga   1200

aatcaatttt ctctacaaat tggtatttta acagagtgat cacaatctat tgtacaaaat   1260

attttaaaca ctatttgtac attcacatat ttggtatgtt taagtaaagt gtgcttgttc   1320

ccaca                                                               1325


<210>  8920
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8920

Met Asn Gln Ala Gly Trp Cys Arg Leu Ser Leu Ser Lys Leu Pro Arg 
1               5                   10                  15


Thr Ala Gly Ile Ser Leu Gly Ile Cys Phe Gly Lys Gly Gln Lys Leu 
            20                  25                  30


Phe Ser Arg Leu His Ala Ser Thr Gln 
        35                  40


<210>  8921
<211>  2543
<212>  DNA
<213>  Homo sapiens

<400>  8921
gacaaactag agagaactgc aaggactcag tacatccctg gcacagtcca ttctctctca     60

cagcatattg tatgagactg tgtgagtgct gcttccacgc tacactaaaa acccatggtc    120

cctgcattat ttgagcaact gacaagcttc tgaagttcag gttcgcgaac gctgagagca    180

gcacccagtg gatttgtggc agatgaggaa actgaggccc agagaggtta agtgattgcc    240

ctgaagccac acagctaacc agagaagata taagttcctg ccttccttac ttcccattct    300

cataagcaag tttccgcatg aacaaggtgg caggtctgag caaaatgcta aaactgtggc    360

cccattttgt ttgtgcacat gtatgtgtgt acatgagcta ttggtgtgac gggagtttgc    420

ggggatattc tctccctgtt acatgttttc acatttccca caagacggga atgaaaagga    480

aggaagagct gaaccattcc ctcaggcaag tagatctgtg gcaaacaaag agtccacagc    540

tcggtctcca cgggggtcag tctgacttcc ttccctcaga agcatcccgg gctacatttt    600

catcttcgcc gtcttccaat cttgcataat ctataataat gtgattccaa atgcatttta    660

gcaaatgcaa gatggaatgg gactcccccg gctgctcccg aacatctgat ctaagaaacc    720

cgtaaggagc tgcagtgaaa agttcactga tagaaaaaaa caaacaaaca aacagacatt    780

tgcctgtgtc cctggttagg ggcaaggctt ttccgggttg gtggctcttg gtcatctttg    840

ttgtccttaa aaaagggata acgctgagga gctggcggtt cacctttgct cttgtgttta    900

attgctgcaa aagccactta ttaccttgtg ttcttccgca gagggcacac tgtctttccc    960

agccaccagg cctgctggtg tttggcttct ctacctgccc cggaagccat ccccgtcacc   1020

tccgagtaat tctgggtcac ttccagggcc aggtctgtct ggctccggta caggaaggcc   1080

ctcatgaaag gaagaagggc ggaactggga tttttttttc tttctttgaa ttttgcataa   1140

aattccgtcc ccagccacct aatgagaaaa catccatcat ctatctttcc ctgggaatgt   1200

cggtggccat tctgagctgg tttgtggtcc cgctcatctg tacgcaggca gggcttgtga   1260

aattgctttt ccctcagaaa aatatgttca tttccacctt cctcagatgg ccctcacaaa   1320

tgaaagtgct ttgtcatttt taatgcccag tgttcccttt ttcccgcact gtctccagtc   1380

acgatccagc cgataaaacc cacaggtaca tttaaaacaa aaaacaaaaa acaaaacaca   1440

cacacacaca cacacacaca cacacacaca cctcaaaagc ccagaggact gtcagattcc   1500

actggtgtcc ccttgtgggt tttcctggca cacagagcaa aaatggctgc aaggggaggt   1560

tctctctctg ttccctggaa atctccttgg gccttgtgca gcatttggat ggacacgcag   1620

cgacagggga cgtgctgaat tctagataac agatgcctgc cttaaaatgg aggcacaaag   1680

cccagccctg tccccttggc tggccggctc tgagcatcct gagaattaac agaggtacat   1740

gtgctttata aaaactggaa agtgtactaa aaattcaaag ttattattat ttctaaaatg   1800

tctccagcct acgatttgtc ataaacacct atcattctgc atagataatt gggtaattgt   1860

tcctcatgcc agagggaaca aacgtctctc tttgaaatgt gtgtggaggc ttacacatag   1920

agagccctgt tataacgagg gtctgactcc atagagattt gtagatgcca aaagactaac   1980

aataacctcc tccaaaaaat aactgcatcc agcttttcat aggcaagtta gtaggaccac   2040

ctgattccag cattttaaaa gagtcaccct ctatatggaa atgtggtcaa aatactagtc   2100

caggaaagga acatgacaga tttgttggcc aaaacttatt tcaaagcaga atctttgtaa   2160

aatatgattt ttttcccaca tatctgcatt tcaagactgg gttatctttg tttctttgtg   2220

attgttattt aaatacatat tagttttaac ttttcctacc ttttcttgat cacaccatcc   2280

gctgagttaa ggatctgtaa acaaagcttg aattgagcca aaatgatcta acttccaaag   2340

ggaacccttg tttcctcagg taaacttgaa cgtcttcatt gatgatagag aaccttgctt   2400

ctcaaataac ctagcatgaa gggcaacttg gtagttgttt ttgttgctaa tatccaattc   2460

cccatggcct gatacttttg taaaatacat aacagttgaa ttactagaaa aataaaatgt   2520

cgcttgaatg ttgcagtcat gtc                                           2543


<210>  8922
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  8922

Met Asn Lys Val Ala Gly Leu Ser Lys Met Leu Lys Leu Trp Pro His 
1               5                   10                  15


Phe Val Cys Ala His Val Cys Val Tyr Met Ser Tyr Trp Cys Asp Gly 
            20                  25                  30


Ser Leu Arg Gly Tyr Ser Leu Pro Val Thr Cys Phe His Ile Ser His 
        35                  40                  45


Lys Thr Gly Met Lys Arg Lys Glu Glu Leu Asn His Ser Leu Arg Gln 
    50                  55                  60


Val Asp Leu Trp Gln Thr Lys Ser Pro Gln Leu Gly Leu His Gly Gly 
65                  70                  75                  80


Gln Ser Asp Phe Leu Pro Ser Glu Ala Ser Arg Ala Thr Phe Ser Ser 
                85                  90                  95


Ser Pro Ser Ser Asn Leu Ala 
            100


<210>  8923
<211>  942
<212>  DNA
<213>  Homo sapiens

<400>  8923
gacaaactag agagaactgc aaggactcag tacatccctg gcacagtcca ttctctctca     60

cagcatattg tatgagactg tgtgagtgct gcttccacgc tacactaaaa acccatggtc    120

cctgcattat ttgagcaact gacaagcttc tgaagttcag gttcgcgaac gctgagagca    180

gcacccagtg gatttgtggc agatttttga tgaaccaagc tggctggtgt cgcctcagtt    240

tgtctaaatt accaaggacc gctggaattt ccctgggaat atgtttcggg aaaggtcaga    300

aactcttcag tcgtcttcac gcttccactc agtagcaacg tttttgcaca ctcattgact    360

atcaactggt tgtctatgac tcaaattaca taatgaatcc agcacataaa ttatttactc    420

agatttaatg ccagcaactg ttatctttgt atttttttcc cctctgccag ctaatctggc    480

tcatttcatt ggaattttgg tcatgcccat tctccttctg cactaaatta actccataac    540

gtagtataaa cagaacaagc ttgtgtgtga tatgcttaac tgttaattta cctaattaaa    600

ctaattcaat taaatcattt acatcttttt ggtaacatgc cagttgatac cacagcagaa    660

gtgggatgtt tcagaagatg attgttcagc aaatgaatgg aaaaaaaaat aaaaggaaaa    720

caaaatgaga caaccgtcca aatctcttgg cttgaaaatt aaatgatact gaaaaaatgc    780

agctttcacg gggcactgtg attagatatt tttctgaaat caattttctc tacaaattgg    840

tattttaaca gagtgatcac aatctattgt acaaaatatt ttaaacacta tttgtacatt    900

cacatatttg gtatgtttaa gtaaagtgtg cttgttccca ca                       942


<210>  8924
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8924

Met Asn Gln Ala Gly Trp Cys Arg Leu Ser Leu Ser Lys Leu Pro Arg 
1               5                   10                  15


Thr Ala Gly Ile Ser Leu Gly Ile Cys Phe Gly Lys Gly Gln Lys Leu 
            20                  25                  30


Phe Ser Arg Leu His Ala Ser Thr Gln 
        35                  40


<210>  8925
<211>  619
<212>  DNA
<213>  Homo sapiens

<400>  8925
agagaactgc aaggactcag tacatccctg gcacagtcca ttctctctca cagcatattg     60

tatgagactg tgtgagtgct gcttccacgc tacactaaaa acccatggtc cctgcattat    120

ttgagcaact gacaagcttc tgaagttcag gttcgcgaac gctgagagca gcacccagtg    180

gatttgtggc agatgcccaa agcaaaaaga gtgaagcagt cagaatttca gacactgtga    240

acaactcccc ttggggtacc tctggggctg gcgtctttac atcacgacga cagaaagctg    300

gcccgcacag actatggcca cggcgtctta gaggttttgt ttctctgcag gcgtccagtg    360

ctctgtttct ttccctcctc accactctcc aaaccacact cacacaaata cacgtcccta    420

tgtgcaaaga cgcgcatatg tatattgtat atcagtgtga cactcacaca tacgtgcggt    480

gttagcatag cctttccccc tcgagtccct gttgtgcttc ccagcaccca gcatcctcca    540

aagcaggcag tggcacacta tcactcataa actaaatcca gccactgcct gctttgtaaa    600

taaagttttg ctggaacac                                                 619


<210>  8926
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  8926

Thr Thr Pro Leu Gly Val Pro Leu Gly Leu Ala Ser Leu His His Asp 
1               5                   10                  15


Asp Arg Lys Leu Ala Arg Thr Asp Tyr Gly His Gly Val Leu Glu Val 
            20                  25                  30


Leu Phe Leu Cys Arg Arg Pro Val Leu Cys Phe Phe Pro Ser Ser Pro 
        35                  40                  45


Leu Ser Lys Pro His Ser His Lys Tyr Thr Ser Leu Cys Ala Lys Thr 
    50                  55                  60


Arg Ile Cys Ile Leu Tyr Ile Ser Val Thr Leu Thr His Thr Cys Gly 
65                  70                  75                  80


Val Ser Ile Ala Phe Pro Pro Arg Val Pro Val Val Leu Pro Ser Thr 
                85                  90                  95


Gln His Pro Pro Lys Gln Ala Val Ala His Tyr His Ser 
            100                 105


<210>  8927
<211>  4893
<212>  DNA
<213>  Homo sapiens

<400>  8927
gcggagctcg agcgctgttg tgtgtttgga aggaaggatg ctgctgccaa tttgtgggac     60

cgctgctgcg aggagtgggc gtggcctcgg cggtgtggat gcttgttagg aaagatgctg    120

agtgcttttc agtgaggagt cagggaggtg tgtgtgagag agagagagaa aagagagaga    180

cagagacggg gagagagaga gggagagaga agagagggag gagggaagaa gaaaagacgg    240

agggaggtga ggaggaaggg agggggagag acagagacct agaggggctg aagacccaga    300

cagagctggc agagctactg agaagaggac tggagcgctc tgagagcctc tcaagatctt    360

ttgggggagc ccaataaatg tgaacatggg atctgtcacg ggagctgtcc tcaagacgct    420

acttctgtat ctactcaaaa ttggaacaga gtcgaagctg ggaattccta tgactgtgat    480

gatcctcttg tgtctgcctt gcctcaggca tccttcagca gttcttccga gctctccagc    540

agtcatggtc ctggatttgc aaggctgaat agaagagatg gagctggtgg ctggtctcca    600

cttgtgtcta acaaatacca gtggttgcag attgaccttg gagagagaat ggaggtcacc    660

gctgtggcca ctcaaggggg atatggtagc tccaactggg tgaccagcta cctcctgatg    720

ttcagtgata gtggctggaa ctggaaacaa tatcgccaag aggacagcat ctggggtttt    780

tcaggaaatg caaatgcaga cagtgttgtg tactatagac tccagccttc tatcaaagcc    840

agatttctgc gcttcatccc tttggaatgg aaccccaagg gcagaattgg aatgcgaatc    900

gaagtgttcg gatgtgcata cagatcagaa gtggttgatc ttgatggaaa aagttccctt    960

ctctacagat ttgatcaaaa atccctgagc ccaataaaag acattatttc tttgaaattc   1020

aaaaccatgc agagtgatgg gattctactc cacagggaag ggccaaatgg agatcacatc   1080

acactgcaat taagaagagc aagactcttt ttacttatta attcaggtga agctaaactg   1140

ccttccactt ccaccctggt caatctcacc ctgggcagcc tgctagatga tcagcattgg   1200

cattcagtgc tcatccagcg tttgggcaaa caagtcaact tcacagtgga cgaacacagg   1260

catcatttcc atgcacgggg agaattcaat ctcatgaatc ttgattatga gatcagcttt   1320

ggagggattc cagcacctgg aaaatcagtg tcattcccac atagaaattt tcatggatgt   1380

ttagaaaatc tctattataa tggagtggat atcattgatt tggccaagca gcaaaaacca   1440

cagatcattg ctatgggaaa tgtgtcattt tcttgttcac aaccacaatc tatgcccgtg   1500

acttttctga gctccaggag ttatttagca ctgccagact tctctggaga ggaggaggtt   1560

tctgccactt ttcaatttcg aacttggaat aaggcagggc ttctgctgtt cagtgaactt   1620

cagctgattt cagggggtat cctcctcttt ctgagtgatg gaaaacttaa gtcgaatctc   1680

taccagccag gaaaattacc cagtgacatc acagcaggtg tcgaattaaa tgatgggcag   1740

tggcattctg tctctttatc tgctaaaaag aatcacttga gtgtggcggt ggacggccag   1800

atggcttctg ctgctcctct gctggggcct gagcagattt attcgggtgg cacctattat   1860

tttggaggtt gtcctgacaa aagctttgga tccaaatgta aaagtccact tggtggattt   1920

cagggatgta tgaggctcat ttctatcagc ggcaaagtgg tagatctgat ttcagttcag   1980

caggggtccc ttgggaactt cagtgacctt cagatagact catgtggcat ctcagacagg   2040

tgtttgccca actattgtga acacggtggg gagtgttccc agtcctggag cacctttcat   2100

tgtaactgta ccaacactgg ttacagagga gctacttgcc ataactctat ctatgagcag   2160

tcatgtgaag cctataagca cagaggaaat acttcagggt tttactatat agattcagat   2220

ggaagtggtc ccctggaacc atttcttcta tattgcaata tgaccgaaac tgcatggacc   2280

atcatacagc acaacggctc tgacttaaca agagtcagaa atactaatcc agagaaccca   2340

tatgctgggt ttttcgagta tgtggccagc atggagcaac ttcaggccac tattaaccgt   2400

gcagagcact gtgaacagga gtttacttat tactgcaaga agtcacggct ggtcaataag   2460

caagatggaa cccctctgag ttggtgggta ggaagaacca atgaaacgca aacctactgg   2520

ggaggttctt cgcctgatct tcaaaaatgt acttgtggat tagagggaaa ctgcattgat   2580

tctcagtatt actgcaattg tgatgctgac cggaatgaat ggaccaatga cactggattg   2640

cttgcttata aagaacatct tccagtaact aagatcgtga ttacagacac aggccgactg   2700

cattcagaag cagcttataa actggggcct ctgctctgcc agggagacag atcattttgg   2760

aattcagctt cctttgatac cgaggcttca tatcttcatt ttcctacctt ccacggagaa   2820

cttagcgcgg atgtatcttt cttttttaag acaacagctt catctggggt atttttagag   2880

aacttgggga ttgctgattt tatacggata gagcttcgct ctccgacagt agtgactttt   2940

tcatttgatg tggggaatgg gccttttgaa atctcagtgc agtcacccac ccacttcaac   3000

gacaaccagt ggcaccatgt gagggttgaa aggaacatga aggaggcctc ccttcaagtg   3060

gatcagctga caccaaagac acagcccgcc cccgctgatg ggcatgtcct gttacagctc   3120

aacagtcagc tcttcgtggg tggaacggcc accagacaga gaggctttct gggctgcatt   3180

cggtctctgc agttgaatgg gatgaccctg gatttggaag aaagagccca ggtgactcca   3240

gaagtgcagc caggttgtag gggacattgc agcagctatg ggaagttatg ccgcaatgga   3300

gggaaatgca gagaaagacc cattgggttc ttttgtgact gcactttctc tgcatacaca   3360

gggccattct gctcaaatga gatttctgca tattttggat ctggctcatc cgtgatatac   3420

aattttcaag aaaattatct tttaagtaaa aactccagct cccacgctgc ttcatttcat   3480

ggtgatatga agctgagcag agaaatgatc aaatttagtt tccgaacaac acgaacacca   3540

agcttgctgc tttttgtgag ctccttttac aaagaatacc tttctgtgat cattgccaaa   3600

aatggaagtt tgcagatcag gtacaagtta aataaatatc aagagcctga tgttgttaac   3660

tttgatttta aaaacatggc tgatggacaa cttcaccaca taatgattaa cagagaagaa   3720

ggagtggtct ttatagagat tgacgataat agaaggagac aagttcacct gtcatcaggc   3780

acagaattca gtgcagtcaa atctctggta ttgggcagga ttttagaaca cagtgatgtg   3840

gaccaggata ctgcactggc aggtgcgcag ggcttcacag gctgcctctc tgcagtgcag   3900

ctcagccacg tggcccctct gaaggcagct ctgcacccca gccacccaga ccctgtcact   3960

gttacaggac acgtgactga gtccagctgt atggcccagc ctggcactga tgccacatca   4020

agggaaagga cacactcgtt tgcagatcat tctggaacaa tagatgacag agagcccctt   4080

gctaatgcaa tcaaaagtga ctctgcagta attggaggtc tgatagctgt tgtgattttt   4140

atcttgcttt gcatcactgc catagctgtt cgcatttatc agcagaaaag gttatataaa   4200

agaagtgagg caaaaaggtc agagaatgta gacagtgctg aggctgttct gaaaagtgag   4260

cttaatatac aaaatgcagt caatgaaaat cagaaagagt acttcttctg attggcagct   4320

atgatttaac ataaaattat gatagtttgt tttaatagcc aggggttctc aatggaaaaa   4380

cgaatgctct tacactgaat gtacaggcag tgggcttgca gcactgccat cttgccatgt   4440

acaggcttgg ggtggctcca ggaagcctcg tccagtgata tatttctcat agcattcatt   4500

ctatggaaca agaaattaga tattgctgtt aattttcaac tgttctggta tgatctaaaa   4560

caagtttaac ctgcttaatg gctacagttt ttacatgtga aaactgtagc cttggtctct   4620

taaccatgta atacataagt tttgttagag gtaaaaatta aatttggact ataatgtcct   4680

tgctttattt gagaacattt gctgtgtttg cttttgtctc ctcgtggtgt tattcataga   4740

cctggaaatg cttctcagat cctgtgtggc cggtgtttgc atcttcagtg gccacaagca   4800

taataaagcc cctttgcctt tctctgtatt atattcaata caatacatca atagtcttga   4860

aaaatgtttt gctgtctttg ctttgtttgt att                                4893


<210>  8928
<211>  1220
<212>  PRT
<213>  Homo sapiens

<400>  8928

Met Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn 
1               5                   10                  15


Trp Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp 
            20                  25                  30


Lys Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala 
        35                  40                  45


Asn Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala 
    50                  55                  60


Arg Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile 
65                  70                  75                  80


Gly Met Arg Ile Glu Val Phe Gly Cys Ala Tyr Arg Ser Glu Val Val 
                85                  90                  95


Asp Leu Asp Gly Lys Ser Ser Leu Leu Tyr Arg Phe Asp Gln Lys Ser 
            100                 105                 110


Leu Ser Pro Ile Lys Asp Ile Ile Ser Leu Lys Phe Lys Thr Met Gln 
        115                 120                 125


Ser Asp Gly Ile Leu Leu His Arg Glu Gly Pro Asn Gly Asp His Ile 
    130                 135                 140


Thr Leu Gln Leu Arg Arg Ala Arg Leu Phe Leu Leu Ile Asn Ser Gly 
145                 150                 155                 160


Glu Ala Lys Leu Pro Ser Thr Ser Thr Leu Val Asn Leu Thr Leu Gly 
                165                 170                 175


Ser Leu Leu Asp Asp Gln His Trp His Ser Val Leu Ile Gln Arg Leu 
            180                 185                 190


Gly Lys Gln Val Asn Phe Thr Val Asp Glu His Arg His His Phe His 
        195                 200                 205


Ala Arg Gly Glu Phe Asn Leu Met Asn Leu Asp Tyr Glu Ile Ser Phe 
    210                 215                 220


Gly Gly Ile Pro Ala Pro Gly Lys Ser Val Ser Phe Pro His Arg Asn 
225                 230                 235                 240


Phe His Gly Cys Leu Glu Asn Leu Tyr Tyr Asn Gly Val Asp Ile Ile 
                245                 250                 255


Asp Leu Ala Lys Gln Gln Lys Pro Gln Ile Ile Ala Met Gly Asn Val 
            260                 265                 270


Ser Phe Ser Cys Ser Gln Pro Gln Ser Met Pro Val Thr Phe Leu Ser 
        275                 280                 285


Ser Arg Ser Tyr Leu Ala Leu Pro Asp Phe Ser Gly Glu Glu Glu Val 
    290                 295                 300


Ser Ala Thr Phe Gln Phe Arg Thr Trp Asn Lys Ala Gly Leu Leu Leu 
305                 310                 315                 320


Phe Ser Glu Leu Gln Leu Ile Ser Gly Gly Ile Leu Leu Phe Leu Ser 
                325                 330                 335


Asp Gly Lys Leu Lys Ser Asn Leu Tyr Gln Pro Gly Lys Leu Pro Ser 
            340                 345                 350


Asp Ile Thr Ala Gly Val Glu Leu Asn Asp Gly Gln Trp His Ser Val 
        355                 360                 365


Ser Leu Ser Ala Lys Lys Asn His Leu Ser Val Ala Val Asp Gly Gln 
    370                 375                 380


Met Ala Ser Ala Ala Pro Leu Leu Gly Pro Glu Gln Ile Tyr Ser Gly 
385                 390                 395                 400


Gly Thr Tyr Tyr Phe Gly Gly Cys Pro Asp Lys Ser Phe Gly Ser Lys 
                405                 410                 415


Cys Lys Ser Pro Leu Gly Gly Phe Gln Gly Cys Met Arg Leu Ile Ser 
            420                 425                 430


Ile Ser Gly Lys Val Val Asp Leu Ile Ser Val Gln Gln Gly Ser Leu 
        435                 440                 445


Gly Asn Phe Ser Asp Leu Gln Ile Asp Ser Cys Gly Ile Ser Asp Arg 
    450                 455                 460


Cys Leu Pro Asn Tyr Cys Glu His Gly Gly Glu Cys Ser Gln Ser Trp 
465                 470                 475                 480


Ser Thr Phe His Cys Asn Cys Thr Asn Thr Gly Tyr Arg Gly Ala Thr 
                485                 490                 495


Cys His Asn Ser Ile Tyr Glu Gln Ser Cys Glu Ala Tyr Lys His Arg 
            500                 505                 510


Gly Asn Thr Ser Gly Phe Tyr Tyr Ile Asp Ser Asp Gly Ser Gly Pro 
        515                 520                 525


Leu Glu Pro Phe Leu Leu Tyr Cys Asn Met Thr Glu Thr Ala Trp Thr 
    530                 535                 540


Ile Ile Gln His Asn Gly Ser Asp Leu Thr Arg Val Arg Asn Thr Asn 
545                 550                 555                 560


Pro Glu Asn Pro Tyr Ala Gly Phe Phe Glu Tyr Val Ala Ser Met Glu 
                565                 570                 575


Gln Leu Gln Ala Thr Ile Asn Arg Ala Glu His Cys Glu Gln Glu Phe 
            580                 585                 590


Thr Tyr Tyr Cys Lys Lys Ser Arg Leu Val Asn Lys Gln Asp Gly Thr 
        595                 600                 605


Pro Leu Ser Trp Trp Val Gly Arg Thr Asn Glu Thr Gln Thr Tyr Trp 
    610                 615                 620


Gly Gly Ser Ser Pro Asp Leu Gln Lys Cys Thr Cys Gly Leu Glu Gly 
625                 630                 635                 640


Asn Cys Ile Asp Ser Gln Tyr Tyr Cys Asn Cys Asp Ala Asp Arg Asn 
                645                 650                 655


Glu Trp Thr Asn Asp Thr Gly Leu Leu Ala Tyr Lys Glu His Leu Pro 
            660                 665                 670


Val Thr Lys Ile Val Ile Thr Asp Thr Gly Arg Leu His Ser Glu Ala 
        675                 680                 685


Ala Tyr Lys Leu Gly Pro Leu Leu Cys Gln Gly Asp Arg Ser Phe Trp 
    690                 695                 700


Asn Ser Ala Ser Phe Asp Thr Glu Ala Ser Tyr Leu His Phe Pro Thr 
705                 710                 715                 720


Phe His Gly Glu Leu Ser Ala Asp Val Ser Phe Phe Phe Lys Thr Thr 
                725                 730                 735


Ala Ser Ser Gly Val Phe Leu Glu Asn Leu Gly Ile Ala Asp Phe Ile 
            740                 745                 750


Arg Ile Glu Leu Arg Ser Pro Thr Val Val Thr Phe Ser Phe Asp Val 
        755                 760                 765


Gly Asn Gly Pro Phe Glu Ile Ser Val Gln Ser Pro Thr His Phe Asn 
    770                 775                 780


Asp Asn Gln Trp His His Val Arg Val Glu Arg Asn Met Lys Glu Ala 
785                 790                 795                 800


Ser Leu Gln Val Asp Gln Leu Thr Pro Lys Thr Gln Pro Ala Pro Ala 
                805                 810                 815


Asp Gly His Val Leu Leu Gln Leu Asn Ser Gln Leu Phe Val Gly Gly 
            820                 825                 830


Thr Ala Thr Arg Gln Arg Gly Phe Leu Gly Cys Ile Arg Ser Leu Gln 
        835                 840                 845


Leu Asn Gly Met Thr Leu Asp Leu Glu Glu Arg Ala Gln Val Thr Pro 
    850                 855                 860


Glu Val Gln Pro Gly Cys Arg Gly His Cys Ser Ser Tyr Gly Lys Leu 
865                 870                 875                 880


Cys Arg Asn Gly Gly Lys Cys Arg Glu Arg Pro Ile Gly Phe Phe Cys 
                885                 890                 895


Asp Cys Thr Phe Ser Ala Tyr Thr Gly Pro Phe Cys Ser Asn Glu Ile 
            900                 905                 910


Ser Ala Tyr Phe Gly Ser Gly Ser Ser Val Ile Tyr Asn Phe Gln Glu 
        915                 920                 925


Asn Tyr Leu Leu Ser Lys Asn Ser Ser Ser His Ala Ala Ser Phe His 
    930                 935                 940


Gly Asp Met Lys Leu Ser Arg Glu Met Ile Lys Phe Ser Phe Arg Thr 
945                 950                 955                 960


Thr Arg Thr Pro Ser Leu Leu Leu Phe Val Ser Ser Phe Tyr Lys Glu 
                965                 970                 975


Tyr Leu Ser Val Ile Ile Ala Lys Asn Gly Ser Leu Gln Ile Arg Tyr 
            980                 985                 990


Lys Leu Asn Lys Tyr Gln Glu Pro Asp Val Val Asn Phe Asp Phe Lys 
        995                 1000                1005


Asn Met Ala Asp Gly Gln Leu His His Ile Met Ile Asn Arg Glu Glu 
    1010                1015                1020


Gly Val Val Phe Ile Glu Ile Asp Asp Asn Arg Arg Arg Gln Val His 
1025                1030                1035                1040


Leu Ser Ser Gly Thr Glu Phe Ser Ala Val Lys Ser Leu Val Leu Gly 
                1045                1050                1055


Arg Ile Leu Glu His Ser Asp Val Asp Gln Asp Thr Ala Leu Ala Gly 
            1060                1065                1070


Ala Gln Gly Phe Thr Gly Cys Leu Ser Ala Val Gln Leu Ser His Val 
        1075                1080                1085


Ala Pro Leu Lys Ala Ala Leu His Pro Ser His Pro Asp Pro Val Thr 
    1090                1095                1100


Val Thr Gly His Val Thr Glu Ser Ser Cys Met Ala Gln Pro Gly Thr 
1105                1110                1115                1120


Asp Ala Thr Ser Arg Glu Arg Thr His Ser Phe Ala Asp His Ser Gly 
                1125                1130                1135


Thr Ile Asp Asp Arg Glu Pro Leu Ala Asn Ala Ile Lys Ser Asp Ser 
            1140                1145                1150


Ala Val Ile Gly Gly Leu Ile Ala Val Val Ile Phe Ile Leu Leu Cys 
        1155                1160                1165


Ile Thr Ala Ile Ala Val Arg Ile Tyr Gln Gln Lys Arg Leu Tyr Lys 
    1170                1175                1180


Arg Ser Glu Ala Lys Arg Ser Glu Asn Val Asp Ser Ala Glu Ala Val 
1185                1190                1195                1200


Leu Lys Ser Glu Leu Asn Ile Gln Asn Ala Val Asn Glu Asn Gln Lys 
                1205                1210                1215


Glu Tyr Phe Phe 
            1220


<210>  8929
<211>  851
<212>  DNA
<213>  Homo sapiens

<400>  8929
gagtgggcgt ggcctcggcg gtgtggatgc ttgttaggaa agatgctgag tgcttttcag     60

tgaggagtca gggaggtgtg tgtgagagag agagagaaaa gagagagaca gagacgggga    120

gagagagagg gagagagaag agagggagga gggaagaaga aaagacggag ggaggtgagg    180

aggaagggag ggggagagac agagacctag aggggctgaa gacccagaca gagctggcag    240

agctactgag aagaggactg gagcgctctg agagcctctc aagatctttt gggggagccc    300

aataaatgtg aacatgggat ctgtcacggg agctgtcctc aagacgctac ttctgtatct    360

actcaaaatt ggaacagagt cgaagctggg aattcctatg actgtgatga tcctcttgtg    420

tctgccttgc ctcaggcatc cttcagcagt tcttccgagc tctccagcag tcatggtcct    480

ggatttgcaa ggctgaatag aagagatgga gctggtggct ggtctccact tgtgtctaac    540

aaataccagt ggttgcagat tgaccttgga gagagaatgg aggtcaccgc tgtggccact    600

caagggggat atggtagctc caactgggtg accagctacc tcctgatgtt cagtgatagt    660

ggctggaact ggaaacaata tcgccaagag gacagcatct ggggtttttc aggaaatgca    720

aatgcagaca gtgttgtgta ctatagactc cagccttcta tcaaagccag atttctgcgc    780

ttcatccctt tggaatggaa ccccaagggc agaattggaa tgcgaatcga agtgttcgga    840

tgtgcataca g                                                         851


<210>  8930
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  8930

Met Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn 
1               5                   10                  15


Trp Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp 
            20                  25                  30


Lys Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala 
        35                  40                  45


Asn Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala 
    50                  55                  60


Arg Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile 
65                  70                  75                  80


Gly Met Arg Ile Glu Val Phe Gly Cys Ala 
                85                  90


<210>  8931
<211>  4677
<212>  DNA
<213>  Homo sapiens

<400>  8931
gagtgggcgt ggcctcggcg gtgtggatgc ttgttaggaa agatgctgag tgcttttcag     60

tgaggagtca gggaggtgtg tgtgagagag agagagaaaa gagagagaca gagacgggga    120

gagagagagg gagagagaag agagggagga gggaagaaga aaagacggag ggaggtgagg    180

aggaagggag ggggagagac agagacctag aggggctgaa gacccagaca gagctggcag    240

agctactgag aagaggactg gagcgctctg agagcctctc aagatctttt gggggagccc    300

aataaatgtg aacatgggat ctgtcacggg agctgtcctc aagacgctac ttctgtatct    360

actcaaaatt ggaacagagt cgaagctggg aattcctatg actgtgatga tcctcttgtg    420

tctgccttgc ctcaggcatc cttcagcagt tcttccgagc tctccagcag tcatggtcct    480

ggatttgcaa ggctgaatag aagagatgga gctggtggct ggtctccact tgtgtctaac    540

aaataccagt ggttgcagat tgaccttgga gagagaatgg aggtcaccgc tgtggccact    600

caagggggat atggtagctc caactgggtg accagctacc tcctgatgtt cagtgatagt    660

ggctggaact ggaaacaata tcgccaagag gacagcatct ggggtttttc aggaaatgca    720

aatgcagaca gtgttgtgta ctatagactc cagccttcta tcaaagccag atttctgcgc    780

ttcatccctt tggaatggaa ccccaagggc agaattggaa tgcgaatcga agtgttcgga    840

tgtgcataca gatcagaagt ggttgatctt gatggaaaaa gttcccttct ctacagattt    900

gatcaaaaat ccctgagccc aataaaagac attatttctt tgaaattcaa aaccatgcag    960

agtgatggga ttctactcca cagggaaggg ccaaatggag atcacatcac actgcaatta   1020

agaagagcaa gactcttttt acttattaat tcaggtgaag ctaaactgcc ttccacttcc   1080

accctggtca atctcaccct gggcagcctg ctagatgatc agcattggca ttcagtgctc   1140

atccagcgtt tgggcaaaca agtcaacttc acagtggacg aacacaggca tcatttccat   1200

gcacggggag aattcaatct catgaatctt gattatgagg gaaatgtgtc attttcttgt   1260

tcacaaccac aatctatgcc cgtgactttt ctgagctcca ggagttattt agcactgcca   1320

gacttctctg gagaggagga ggtttctgcc acttttcaat ttcgaacttg gaataaggca   1380

gggcttctgc tgttcagtga acttcagctg atttcagggg gtatcctcct ctttctgagt   1440

gatggaaaac ttaagtcgaa tctctaccag ccaggaaaat tacccagtga catcacagca   1500

ggtgtcgaat taaatgatgg gcagtggcat tctgtctctt tatctgctaa aaagaatcac   1560

ttgagtgtgg cggtggacgg ccagatggct tctgctgctc ctctgctggg gcctgagcag   1620

atttattcgg gtggcaccta ttattttgga ggttgtcctg acaaaagctt tggatccaaa   1680

tgtaaaagtc cacttggtgg atttcaggga tgtatgaggc tcatttctat cagcggcaaa   1740

gtggtagatc tgatttcagt tcagcagggg tcccttggga acttcagtga ccttcagata   1800

gactcatgtg gcatctcaga caggtgtttg cccaactatt gtgaacacgg tggggagtgt   1860

tcccagtcct ggagcacctt tcattgtaac tgtaccaaca ctggttacag aggagctact   1920

tgccataact ctatctatga gcagtcatgt gaagcctata agcacagagg aaatacttca   1980

gggttttact atatagattc agatggaagt ggtcccctgg aaccatttct tctatattgc   2040

aatatgaccg aaactgcatg gaccatcata cagcacaacg gctctgactt aacaagagtc   2100

agaaatacta atccagagaa cccatatgct gggtttttcg agtatgtggc cagcatggag   2160

caacttcagg ccactattaa ccgtgcagag cactgtgaac aggagtttac ttattactgc   2220

aagaagtcac ggctggtcaa taagcaagat ggaacccctc tgagttggtg ggtaggaaga   2280

accaatgaaa cgcaaaccta ctggggaggt tcttcgcctg atcttcaaaa atgtacttgt   2340

ggattagagg gaaactgcat tgattctcag tattactgca attgtgatgc tgaccggaat   2400

gaatggacca atgacactgg attgcttgct tataaagaac atcttccagt aactaagatc   2460

gtgattacag acacaggccg actgcattca gaagcagctt ataaactggg gcctctgctc   2520

tgccagggag acagatcatt ttggaattca gcttcctttg ataccgaggc ttcatatctt   2580

cattttccta ccttccacgg agaacttagc gcggatgtat ctttcttttt taagacaaca   2640

gcttcatctg gggtattttt agagaacttg gggattgctg attttatacg gatagagctt   2700

cgctctccga cagtagtgac tttttcattt gatgtgggga atgggccttt tgaaatctca   2760

gtgcagtcac ccacccactt caacgacaac cagtggcacc atgtgagggt tgaaaggaac   2820

atgaaggagg cctcccttca agtggatcag ctgacaccaa agacacagcc cgcccccgct   2880

gatgggcatg tcctgttaca gctcaacagt cagctcttcg tgggtggaac ggccaccaga   2940

cagagaggct ttctgggctg cattcggtct ctgcagttga atgggatgac cctggatttg   3000

gaagaaagag cccaggtgac tccagaagtg cagccaggtt gtaggggaca ttgcagcagc   3060

tatgggaagt tatgccgcaa tggagggaaa tgcagagaaa gacccattgg gttcttttgt   3120

gactgcactt tctctgcata cacagggcca ttctgctcaa atgagatttc tgcatatttt   3180

ggatctggct catccgtgat atacaatttt caagaaaatt atcttttaag taaaaactcc   3240

agctcccacg ctgcttcatt tcatggtgat atgaagctga gcagagaaat gatcaaattt   3300

agtttccgaa caacacgaac accaagcttg ctgctttttg tgagctcctt ttacaaagaa   3360

tacctttctg tgatcattgc caaaaatgga agtttgcaga tcaggtacaa gttaaataaa   3420

tatcaagagc ctgatgttgt taactttgat tttaaaaaca tggctgatgg acaacttcac   3480

cacataatga ttaacagaga agaaggagtg gtctttatag agattgacga taatagaagg   3540

agacaagttc acctgtcatc aggcacagaa ttcagtgcag tcaaatctct ggtattgggc   3600

aggattttag aacacagtga tgtggaccag gatactgcac tggcaggtgc gcagggcttc   3660

acaggctgcc tctctgcagt gcagctcagc cacgtggccc ctctgaaggc agctctgcac   3720

cccagccacc cagaccctgt cactgttaca ggacacgtga ctgagtccag ctgtatggcc   3780

cagcctggca ctgatgccac atcaagggaa aggacacact cgtttgcaga tcattctgga   3840

acaatagatg acagagagcc ccttgctaat gcaatcaaaa gtgactctgc agtaattgga   3900

ggtctgatag ctgttgtgat ttttatcttg ctttgcatca ctgccatagc tgttcgcatt   3960

tatcagcaga aaaggttata taaaagaagt gaggcaaaaa ggtcagagaa tgtagacagt   4020

gctgaggctg ttctgaaaag tgagcttaat atacaaaatg cagtcaatga aaatcagaaa   4080

gagtacttct tctgattggc agctatgatt taacataaaa ttatgatagt ttgttttaat   4140

agccaggggt tctcaatgga aaaacgaatg ctcttacact gaatgtacag gcagtgggct   4200

tgcagcactg ccatcttgcc atgtacaggc ttggggtggc tccaggaagc ctcgtccagt   4260

gatatatttc tcatagcatt cattctatgg aacaagaaat tagatattgc tgttaatttt   4320

caactgttct ggtatgatct aaaacaagtt taacctgctt aatggctaca gtttttacat   4380

gtgaaaactg tagccttggt ctcttaacca tgtaatacat aagttttgtt agaggtaaaa   4440

attaaatttg gactataatg tccttgcttt atttgagaac atttgctgtg tttgcttttg   4500

tctcctcgtg gtgttattca tagacctgga aatgcttctc agatcctgtg tggccggtgt   4560

ttgcatcttc agtggccaca agcataataa agcccctttg cctttctctg tattatattc   4620

aatacaatac atcaatagtc ttgaaaaatg ttttgctgtc tttgctttgt ttgtatt      4677


<210>  8932
<211>  1172
<212>  PRT
<213>  Homo sapiens

<400>  8932

Met Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn 
1               5                   10                  15


Trp Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp 
            20                  25                  30


Lys Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala 
        35                  40                  45


Asn Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala 
    50                  55                  60


Arg Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile 
65                  70                  75                  80


Gly Met Arg Ile Glu Val Phe Gly Cys Ala Tyr Arg Ser Glu Val Val 
                85                  90                  95


Asp Leu Asp Gly Lys Ser Ser Leu Leu Tyr Arg Phe Asp Gln Lys Ser 
            100                 105                 110


Leu Ser Pro Ile Lys Asp Ile Ile Ser Leu Lys Phe Lys Thr Met Gln 
        115                 120                 125


Ser Asp Gly Ile Leu Leu His Arg Glu Gly Pro Asn Gly Asp His Ile 
    130                 135                 140


Thr Leu Gln Leu Arg Arg Ala Arg Leu Phe Leu Leu Ile Asn Ser Gly 
145                 150                 155                 160


Glu Ala Lys Leu Pro Ser Thr Ser Thr Leu Val Asn Leu Thr Leu Gly 
                165                 170                 175


Ser Leu Leu Asp Asp Gln His Trp His Ser Val Leu Ile Gln Arg Leu 
            180                 185                 190


Gly Lys Gln Val Asn Phe Thr Val Asp Glu His Arg His His Phe His 
        195                 200                 205


Ala Arg Gly Glu Phe Asn Leu Met Asn Leu Asp Tyr Glu Gly Asn Val 
    210                 215                 220


Ser Phe Ser Cys Ser Gln Pro Gln Ser Met Pro Val Thr Phe Leu Ser 
225                 230                 235                 240


Ser Arg Ser Tyr Leu Ala Leu Pro Asp Phe Ser Gly Glu Glu Glu Val 
                245                 250                 255


Ser Ala Thr Phe Gln Phe Arg Thr Trp Asn Lys Ala Gly Leu Leu Leu 
            260                 265                 270


Phe Ser Glu Leu Gln Leu Ile Ser Gly Gly Ile Leu Leu Phe Leu Ser 
        275                 280                 285


Asp Gly Lys Leu Lys Ser Asn Leu Tyr Gln Pro Gly Lys Leu Pro Ser 
    290                 295                 300


Asp Ile Thr Ala Gly Val Glu Leu Asn Asp Gly Gln Trp His Ser Val 
305                 310                 315                 320


Ser Leu Ser Ala Lys Lys Asn His Leu Ser Val Ala Val Asp Gly Gln 
                325                 330                 335


Met Ala Ser Ala Ala Pro Leu Leu Gly Pro Glu Gln Ile Tyr Ser Gly 
            340                 345                 350


Gly Thr Tyr Tyr Phe Gly Gly Cys Pro Asp Lys Ser Phe Gly Ser Lys 
        355                 360                 365


Cys Lys Ser Pro Leu Gly Gly Phe Gln Gly Cys Met Arg Leu Ile Ser 
    370                 375                 380


Ile Ser Gly Lys Val Val Asp Leu Ile Ser Val Gln Gln Gly Ser Leu 
385                 390                 395                 400


Gly Asn Phe Ser Asp Leu Gln Ile Asp Ser Cys Gly Ile Ser Asp Arg 
                405                 410                 415


Cys Leu Pro Asn Tyr Cys Glu His Gly Gly Glu Cys Ser Gln Ser Trp 
            420                 425                 430


Ser Thr Phe His Cys Asn Cys Thr Asn Thr Gly Tyr Arg Gly Ala Thr 
        435                 440                 445


Cys His Asn Ser Ile Tyr Glu Gln Ser Cys Glu Ala Tyr Lys His Arg 
    450                 455                 460


Gly Asn Thr Ser Gly Phe Tyr Tyr Ile Asp Ser Asp Gly Ser Gly Pro 
465                 470                 475                 480


Leu Glu Pro Phe Leu Leu Tyr Cys Asn Met Thr Glu Thr Ala Trp Thr 
                485                 490                 495


Ile Ile Gln His Asn Gly Ser Asp Leu Thr Arg Val Arg Asn Thr Asn 
            500                 505                 510


Pro Glu Asn Pro Tyr Ala Gly Phe Phe Glu Tyr Val Ala Ser Met Glu 
        515                 520                 525


Gln Leu Gln Ala Thr Ile Asn Arg Ala Glu His Cys Glu Gln Glu Phe 
    530                 535                 540


Thr Tyr Tyr Cys Lys Lys Ser Arg Leu Val Asn Lys Gln Asp Gly Thr 
545                 550                 555                 560


Pro Leu Ser Trp Trp Val Gly Arg Thr Asn Glu Thr Gln Thr Tyr Trp 
                565                 570                 575


Gly Gly Ser Ser Pro Asp Leu Gln Lys Cys Thr Cys Gly Leu Glu Gly 
            580                 585                 590


Asn Cys Ile Asp Ser Gln Tyr Tyr Cys Asn Cys Asp Ala Asp Arg Asn 
        595                 600                 605


Glu Trp Thr Asn Asp Thr Gly Leu Leu Ala Tyr Lys Glu His Leu Pro 
    610                 615                 620


Val Thr Lys Ile Val Ile Thr Asp Thr Gly Arg Leu His Ser Glu Ala 
625                 630                 635                 640


Ala Tyr Lys Leu Gly Pro Leu Leu Cys Gln Gly Asp Arg Ser Phe Trp 
                645                 650                 655


Asn Ser Ala Ser Phe Asp Thr Glu Ala Ser Tyr Leu His Phe Pro Thr 
            660                 665                 670


Phe His Gly Glu Leu Ser Ala Asp Val Ser Phe Phe Phe Lys Thr Thr 
        675                 680                 685


Ala Ser Ser Gly Val Phe Leu Glu Asn Leu Gly Ile Ala Asp Phe Ile 
    690                 695                 700


Arg Ile Glu Leu Arg Ser Pro Thr Val Val Thr Phe Ser Phe Asp Val 
705                 710                 715                 720


Gly Asn Gly Pro Phe Glu Ile Ser Val Gln Ser Pro Thr His Phe Asn 
                725                 730                 735


Asp Asn Gln Trp His His Val Arg Val Glu Arg Asn Met Lys Glu Ala 
            740                 745                 750


Ser Leu Gln Val Asp Gln Leu Thr Pro Lys Thr Gln Pro Ala Pro Ala 
        755                 760                 765


Asp Gly His Val Leu Leu Gln Leu Asn Ser Gln Leu Phe Val Gly Gly 
    770                 775                 780


Thr Ala Thr Arg Gln Arg Gly Phe Leu Gly Cys Ile Arg Ser Leu Gln 
785                 790                 795                 800


Leu Asn Gly Met Thr Leu Asp Leu Glu Glu Arg Ala Gln Val Thr Pro 
                805                 810                 815


Glu Val Gln Pro Gly Cys Arg Gly His Cys Ser Ser Tyr Gly Lys Leu 
            820                 825                 830


Cys Arg Asn Gly Gly Lys Cys Arg Glu Arg Pro Ile Gly Phe Phe Cys 
        835                 840                 845


Asp Cys Thr Phe Ser Ala Tyr Thr Gly Pro Phe Cys Ser Asn Glu Ile 
    850                 855                 860


Ser Ala Tyr Phe Gly Ser Gly Ser Ser Val Ile Tyr Asn Phe Gln Glu 
865                 870                 875                 880


Asn Tyr Leu Leu Ser Lys Asn Ser Ser Ser His Ala Ala Ser Phe His 
                885                 890                 895


Gly Asp Met Lys Leu Ser Arg Glu Met Ile Lys Phe Ser Phe Arg Thr 
            900                 905                 910


Thr Arg Thr Pro Ser Leu Leu Leu Phe Val Ser Ser Phe Tyr Lys Glu 
        915                 920                 925


Tyr Leu Ser Val Ile Ile Ala Lys Asn Gly Ser Leu Gln Ile Arg Tyr 
    930                 935                 940


Lys Leu Asn Lys Tyr Gln Glu Pro Asp Val Val Asn Phe Asp Phe Lys 
945                 950                 955                 960


Asn Met Ala Asp Gly Gln Leu His His Ile Met Ile Asn Arg Glu Glu 
                965                 970                 975


Gly Val Val Phe Ile Glu Ile Asp Asp Asn Arg Arg Arg Gln Val His 
            980                 985                 990


Leu Ser Ser Gly Thr Glu Phe Ser Ala Val Lys Ser Leu Val Leu Gly 
        995                 1000                1005


Arg Ile Leu Glu His Ser Asp Val Asp Gln Asp Thr Ala Leu Ala Gly 
    1010                1015                1020


Ala Gln Gly Phe Thr Gly Cys Leu Ser Ala Val Gln Leu Ser His Val 
1025                1030                1035                1040


Ala Pro Leu Lys Ala Ala Leu His Pro Ser His Pro Asp Pro Val Thr 
                1045                1050                1055


Val Thr Gly His Val Thr Glu Ser Ser Cys Met Ala Gln Pro Gly Thr 
            1060                1065                1070


Asp Ala Thr Ser Arg Glu Arg Thr His Ser Phe Ala Asp His Ser Gly 
        1075                1080                1085


Thr Ile Asp Asp Arg Glu Pro Leu Ala Asn Ala Ile Lys Ser Asp Ser 
    1090                1095                1100


Ala Val Ile Gly Gly Leu Ile Ala Val Val Ile Phe Ile Leu Leu Cys 
1105                1110                1115                1120


Ile Thr Ala Ile Ala Val Arg Ile Tyr Gln Gln Lys Arg Leu Tyr Lys 
                1125                1130                1135


Arg Ser Glu Ala Lys Arg Ser Glu Asn Val Asp Ser Ala Glu Ala Val 
            1140                1145                1150


Leu Lys Ser Glu Leu Asn Ile Gln Asn Ala Val Asn Glu Asn Gln Lys 
        1155                1160                1165


Glu Tyr Phe Phe 
    1170


<210>  8933
<211>  2353
<212>  DNA
<213>  Homo sapiens

<400>  8933
gcttttgctg cttcctcatt ttctcttgca gccgccatga ttctgaggcc ttcccagcta     60

tgtggaacta tgactgtgat gatcctcttg tgtctgcctt gcctcaggca tccttcagca    120

gttcttccga gctctccagc agtcatggtc ctggatttgc aaggctgaat agaagagatg    180

gagctggtgg ctggtctcca cttgtgtcta acaaatacca gtggttgcag attgaccttg    240

gagagagaat ggaggtcacc gctgtggcca ctcaaggggg atatggtagc tccaactggg    300

tgaccagcta cctcctgatg ttcagtgata gtggctggaa ctggaaacaa tatcgccaag    360

aggacagcat ctggggtttt tcaggaaatg caaatgcaga cagtgttgtg tactatagac    420

tccagccttc tatcaaagcc agatttctgc gcttcatccc tttggaatgg aaccccaagg    480

gcagaattgg aatgcgaatc gaagtgttcg gatgtgcata cagatcagaa gtggttgatc    540

ttgatggaaa aagttccctt ctctacagat ttgatcaaaa atccctgagc ccaataaaag    600

acattatttc tttgaaattc aaaaccatgc agagtgatgg gattctactc cacagggaag    660

ggccaaatgg agatcacatc acactgcaat taagaagagc aagactcttt ttacttatta    720

attcaggtga agctaaactg ccttccactt ccaccctggt caatctcacc ctgggcagcc    780

tgctagatga tcagcattgg cattcagtgc tcatccagcg tttgggcaaa caagtcaact    840

tcacagtgga cgaacacagg catcatttcc atgcacgggg agaattcaat ctcatgaatc    900

ttgattatga gatcagcttt ggagggattc cagcacctgg aaaatcagtg tcattcccac    960

atagaaattt tcatggatgt ttagaaaatc tctattataa tggagtggat atcattgatt   1020

tggccaagca gcaaaaacca cagatcattg ctatgggaaa tgtgtcattt tcttgttcac   1080

aaccacaatc tatgcccgtg acttttctga gctccaggag ttatttagca ctgccagact   1140

tctctggaga ggaggaggtt tctgccactt ttcaatttcg aacttggaat aaggcagggc   1200

ttctgctgtt cagtgaactt cagctgattt cagggggtat cctcctcttt ctgagtgatg   1260

gaaaacttaa gtcgaatctc taccagccag gaaaattacc cagtgacatc acagcaggtg   1320

tcgaattaaa tgatgggcag tggcattctg tctctttatc tgctaaaaag aatcacttga   1380

gtgtggcggt ggacggccag atggcttctg ctgctcctct gctggggcct gagcagattt   1440

attcgggtgg cacctattat tttggaggtt gtcctgacaa aagctttgga tccaaatgta   1500

aaagtccact tggtggattt cagggatgta tgaggctcat ttctatcagc ggcaaagtgg   1560

tagatctgat ttcagttcag caggggtccc ttgggaactt cagtgacctt cagatagact   1620

catgtggcat ctcagacagg tgtttgccca actattgtga acacggtggg gagtgttccc   1680

agtcctggag cacctttcat tgtaactgta ccaacactgg ttacagagga gctacttgcc   1740

ataactctat ctatgagcag tcatgtgaag cctataagca cagaggaaat acttcagggt   1800

tttactatat agattcagat ggaagtggtc ccctggaacc atttcttcta tattgcaata   1860

tgaccgaaac tgcatggacc atcatacagc acaacggctc tgacttaaca agagtcagaa   1920

atactaatcc agagaaccca tatgctgggt ttttcgagta tgtggccagc atggagcaac   1980

ttcaggccac tattaaccgt gcagagcact gtgaacagga gtttacttat tactgcaaga   2040

agtcacggct ggtcaataag caagatggaa cccctctgag ttggtgggta ggaagaacca   2100

atgaaacgca aacctactgg ggaggttctt cgcctgatct tcaaaaatgt acttgtggat   2160

tagagggaaa ctgcattgat tctcagtatt actgcaattg tgatgctgac cggaatgaat   2220

ggtgatttcc atatgatttc tttatgcaag aaaaagttca tttaaaaaaa ttaatcactc   2280

aaagtatgta tagctagcca gatactgaac aagttagtgc aatgaagtaa ttaaataaag   2340

gtttgtttta atg                                                      2353


<210>  8934
<211>  721
<212>  PRT
<213>  Homo sapiens

<400>  8934

Met Trp Asn Tyr Asp Cys Asp Asp Pro Leu Val Ser Ala Leu Pro Gln 
1               5                   10                  15


Ala Ser Phe Ser Ser Ser Ser Glu Leu Ser Ser Ser His Gly Pro Gly 
            20                  25                  30


Phe Ala Arg Leu Asn Arg Arg Asp Gly Ala Gly Gly Trp Ser Pro Leu 
        35                  40                  45


Val Ser Asn Lys Tyr Gln Trp Leu Gln Ile Asp Leu Gly Glu Arg Met 
    50                  55                  60


Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn Trp 
65                  70                  75                  80


Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp Lys 
                85                  90                  95


Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala Asn 
            100                 105                 110


Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala Arg 
        115                 120                 125


Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile Gly 
    130                 135                 140


Met Arg Ile Glu Val Phe Gly Cys Ala Tyr Arg Ser Glu Val Val Asp 
145                 150                 155                 160


Leu Asp Gly Lys Ser Ser Leu Leu Tyr Arg Phe Asp Gln Lys Ser Leu 
                165                 170                 175


Ser Pro Ile Lys Asp Ile Ile Ser Leu Lys Phe Lys Thr Met Gln Ser 
            180                 185                 190


Asp Gly Ile Leu Leu His Arg Glu Gly Pro Asn Gly Asp His Ile Thr 
        195                 200                 205


Leu Gln Leu Arg Arg Ala Arg Leu Phe Leu Leu Ile Asn Ser Gly Glu 
    210                 215                 220


Ala Lys Leu Pro Ser Thr Ser Thr Leu Val Asn Leu Thr Leu Gly Ser 
225                 230                 235                 240


Leu Leu Asp Asp Gln His Trp His Ser Val Leu Ile Gln Arg Leu Gly 
                245                 250                 255


Lys Gln Val Asn Phe Thr Val Asp Glu His Arg His His Phe His Ala 
            260                 265                 270


Arg Gly Glu Phe Asn Leu Met Asn Leu Asp Tyr Glu Ile Ser Phe Gly 
        275                 280                 285


Gly Ile Pro Ala Pro Gly Lys Ser Val Ser Phe Pro His Arg Asn Phe 
    290                 295                 300


His Gly Cys Leu Glu Asn Leu Tyr Tyr Asn Gly Val Asp Ile Ile Asp 
305                 310                 315                 320


Leu Ala Lys Gln Gln Lys Pro Gln Ile Ile Ala Met Gly Asn Val Ser 
                325                 330                 335


Phe Ser Cys Ser Gln Pro Gln Ser Met Pro Val Thr Phe Leu Ser Ser 
            340                 345                 350


Arg Ser Tyr Leu Ala Leu Pro Asp Phe Ser Gly Glu Glu Glu Val Ser 
        355                 360                 365


Ala Thr Phe Gln Phe Arg Thr Trp Asn Lys Ala Gly Leu Leu Leu Phe 
    370                 375                 380


Ser Glu Leu Gln Leu Ile Ser Gly Gly Ile Leu Leu Phe Leu Ser Asp 
385                 390                 395                 400


Gly Lys Leu Lys Ser Asn Leu Tyr Gln Pro Gly Lys Leu Pro Ser Asp 
                405                 410                 415


Ile Thr Ala Gly Val Glu Leu Asn Asp Gly Gln Trp His Ser Val Ser 
            420                 425                 430


Leu Ser Ala Lys Lys Asn His Leu Ser Val Ala Val Asp Gly Gln Met 
        435                 440                 445


Ala Ser Ala Ala Pro Leu Leu Gly Pro Glu Gln Ile Tyr Ser Gly Gly 
    450                 455                 460


Thr Tyr Tyr Phe Gly Gly Cys Pro Asp Lys Ser Phe Gly Ser Lys Cys 
465                 470                 475                 480


Lys Ser Pro Leu Gly Gly Phe Gln Gly Cys Met Arg Leu Ile Ser Ile 
                485                 490                 495


Ser Gly Lys Val Val Asp Leu Ile Ser Val Gln Gln Gly Ser Leu Gly 
            500                 505                 510


Asn Phe Ser Asp Leu Gln Ile Asp Ser Cys Gly Ile Ser Asp Arg Cys 
        515                 520                 525


Leu Pro Asn Tyr Cys Glu His Gly Gly Glu Cys Ser Gln Ser Trp Ser 
    530                 535                 540


Thr Phe His Cys Asn Cys Thr Asn Thr Gly Tyr Arg Gly Ala Thr Cys 
545                 550                 555                 560


His Asn Ser Ile Tyr Glu Gln Ser Cys Glu Ala Tyr Lys His Arg Gly 
                565                 570                 575


Asn Thr Ser Gly Phe Tyr Tyr Ile Asp Ser Asp Gly Ser Gly Pro Leu 
            580                 585                 590


Glu Pro Phe Leu Leu Tyr Cys Asn Met Thr Glu Thr Ala Trp Thr Ile 
        595                 600                 605


Ile Gln His Asn Gly Ser Asp Leu Thr Arg Val Arg Asn Thr Asn Pro 
    610                 615                 620


Glu Asn Pro Tyr Ala Gly Phe Phe Glu Tyr Val Ala Ser Met Glu Gln 
625                 630                 635                 640


Leu Gln Ala Thr Ile Asn Arg Ala Glu His Cys Glu Gln Glu Phe Thr 
                645                 650                 655


Tyr Tyr Cys Lys Lys Ser Arg Leu Val Asn Lys Gln Asp Gly Thr Pro 
            660                 665                 670


Leu Ser Trp Trp Val Gly Arg Thr Asn Glu Thr Gln Thr Tyr Trp Gly 
        675                 680                 685


Gly Ser Ser Pro Asp Leu Gln Lys Cys Thr Cys Gly Leu Glu Gly Asn 
    690                 695                 700


Cys Ile Asp Ser Gln Tyr Tyr Cys Asn Cys Asp Ala Asp Arg Asn Glu 
705                 710                 715                 720


Trp 



<210>  8935
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  8935
ctgaggcctt cccagctatg tggaactatg actgtgatga tcctcttgtg tctgccttgc     60

ctcaggcatc cttcagcagt tcttccgagc tctccagcag tcatggtcct ggatttgcaa    120

ggctgaatag aagagatgga gctggtggct ggtctccact tgtgtctaac aaataccagt    180

ggttgcagat tgaccttgga gagagaatgg aggtcaccgc tgtggccact caagggggat    240

atggtagctc caactgggtg accagctacc tcctgatgtt cagtgatagt ggctggaact    300

ggaaacaata tcgccaagag gacagcatct ggggtttttc aggaaatgca aatgcagaca    360

gtgttgtgta ctatagactc cagccttcta tcaaagccag atttctgcgc ttcatccctt    420

tggaatggaa ccccaagggc agaattggaa tgcgaatcga agtgttcgga tgtgcataca    480

gtaacagtga tcctgtttgc agatctggag aagaaatgta tagaagtaaa ttactggtgg    540

gag                                                                  543


<210>  8936
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  8936

Met Trp Asn Tyr Asp Cys Asp Asp Pro Leu Val Ser Ala Leu Pro Gln 
1               5                   10                  15


Ala Ser Phe Ser Ser Ser Ser Glu Leu Ser Ser Ser His Gly Pro Gly 
            20                  25                  30


Phe Ala Arg Leu Asn Arg Arg Asp Gly Ala Gly Gly Trp Ser Pro Leu 
        35                  40                  45


Val Ser Asn Lys Tyr Gln Trp Leu Gln Ile Asp Leu Gly Glu Arg Met 
    50                  55                  60


Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn Trp 
65                  70                  75                  80


Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp Lys 
                85                  90                  95


Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala Asn 
            100                 105                 110


Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala Arg 
        115                 120                 125


Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile Gly 
    130                 135                 140


Met Arg Ile Glu Val Phe Gly Cys Ala Tyr Ser Asn Ser Asp Pro Val 
145                 150                 155                 160


Cys Arg Ser Gly Glu Glu Met Tyr Arg Ser Lys Leu Leu Val 
                165                 170


<210>  8937
<211>  4657
<212>  DNA
<213>  Homo sapiens

<400>  8937
tatataattt tatgattttt aaagtatttt catattctcc tgtctttaag ttttttcttt     60

tctcattgaa cttactagac ttctagtaag ccctggaagt agtaggcata tttttagaga    120

tcttagatcc tagtttttga tgttgttgtt ttacttgttg gttgttttgt ctattgattc    180

cacgaaagcc tcagcactaa ctaaccctaa cgtggcattg ttcctcctgg cagatgactg    240

tgatgatcct cttgtgtctg ccttgcctca ggcatccttc agcagttctt ccgagctctc    300

cagcagtcat ggtcctggat ttgcaaggct gaatagaaga gatggagctg gtggctggtc    360

tccacttgtg tctaacaaat accagtggtt gcagattgac cttggagaga gaatggaggt    420

caccgctgtg gccactcaag ggggatatgg tagctccaac tgggtgacca gctacctcct    480

gatgttcagt gatagtggct ggaactggaa acaatatcgc caagaggaca gcatctgggg    540

tttttcagga aatgcaaatg cagacagtgt tgtgtactat agactccagc cttctatcaa    600

agccagattt ctgcgcttca tccctttgga atggaacccc aagggcagaa ttggaatgcg    660

aatcgaagtg ttcggatgtg catacagatc agaagtggtt gatcttgatg gaaaaagttc    720

ccttctctac agatttgatc aaaaatccct gagcccaata aaagacatta tttctttgaa    780

attcaaaacc atgcagagtg atgggattct actccacagg gaagggccaa atggagatca    840

catcacactg caattaagaa gagcaagact ctttttactt attaattcag gtgaagctaa    900

actgccttcc acttccaccc tggtcaatct caccctgggc agcctgctag atgatcagca    960

ttggcattca gtgctcatcc agcgtttggg caaacaagtc aacttcacag tggacgaaca   1020

caggcatcat ttccatgcac ggggagaatt caatctcatg aatcttgatt atgagatcag   1080

ctttggaggg attccagcac ctggaaaatc agtgtcattc ccacatagaa attttcatgg   1140

atgtttagaa aatctctatt ataatggagt ggatatcatt gatttggcca agcagcaaaa   1200

accacagatc attgctatgg gaaatgtgtc attttcttgt tcacaaccac aatctatgcc   1260

cgtgactttt ctgagctcca ggagttattt agcactgcca gacttctctg gagaggagga   1320

ggtttctgcc acttttcaat ttcgaacttg gaataaggca gggcttctgc tgttcagtga   1380

acttcagctg atttcagggg gtatcctcct ctttctgagt gatggaaaac ttaagtcgaa   1440

tctctaccag ccaggaaaat tacccagtga catcacagca ggtgtcgaat taaatgatgg   1500

gcagtggcat tctgtctctt tatctgctaa aaagaatcac ttgagtgtgg cggtggacgg   1560

ccagatggct tctgctgctc ctctgctggg gcctgagcag atttattcgg gtggcaccta   1620

ttattttgga ggttgtcctg acaaaagctt tggatccaaa tgtaaaagtc cacttggtgg   1680

atttcaggga tgtatgaggc tcatttctat cagcggcaaa gtggtagatc tgatttcagt   1740

tcagcagggg tcccttggga acttcagtga ccttcagata gactcatgtg gcatctcaga   1800

caggtgtttg cccaactatt gtgaacacgg tggggagtgt tcccagtcct ggagcacctt   1860

tcattgtaac tgtaccaaca ctggttacag aggagctact tgccataact ctatctatga   1920

gcagtcatgt gaagcctata agcacagagg aaatacttca gggttttact atatagattc   1980

agatggaagt ggtcccctgg aaccatttct tctatattgc aatatgaccg aaactgcatg   2040

gaccatcata cagcacaacg gctctgactt aacaagagtc agaaatacta atccagagaa   2100

cccatatgct gggtttttcg agtatgtggc cagcatggag caacttcagg ccactattaa   2160

ccgtgcagag cactgtgaac aggagtttac ttattactgc aagaagtcac ggctggtcaa   2220

taagcaagat ggaacccctc tgagttggtg ggtaggaaga accaatgaaa cgcaaaccta   2280

ctggggaggt tcttcgcctg atcttcaaaa atgtacttgt ggattagagg gaaactgcat   2340

tgattctcag tattactgca attgtgatgc tgaccggaat gaatggacca atgacactgg   2400

attgcttgct tataaagaac atcttccagt aactaagatc gtgattacag acacaggccg   2460

actgcattca gaagcagctt ataaactggg gcctctgctc tgccagggag acagatcatt   2520

ttggaattca gcttcctttg ataccgaggc ttcatatctt cattttccta ccttccacgg   2580

agaacttagc gcggatgtat ctttcttttt taagacaaca gcttcatctg gggtattttt   2640

agagaacttg gggattgctg attttatacg gatagagctt cgctctccga cagtagtgac   2700

tttttcattt gatgtgggga atgggccttt tgaaatctca gtgcagtcac ccacccactt   2760

caacgacaac cagtggcacc atgtgagggt tgaaaggaac atgaaggagg cctcccttca   2820

agtggatcag ctgacaccaa agacacagcc cgcccccgct gatgggcatg tcctgttaca   2880

gctcaacagt cagctcttcg tgggtggaac ggccaccaga cagagaggct ttctgggctg   2940

cattcggtct ctgcagttga atgggatgac cctggatttg gaagaaagag cccaggtgac   3000

tccagaagtg cagccaggtt gtaggggaca ttgcagcagc tatgggaagt tatgccgcaa   3060

tggagggaaa tgcagagaaa gacccattgg gttcttttgt gactgcactt tctctgcata   3120

cacagggcca ttctgctcaa atgagatttc tgcatatttt ggatctggct catccgtgat   3180

atacaatttt caagaaaatt atcttttaag taaaaactcc agctcccacg ctgcttcatt   3240

tcatggtgat atgaagctga gcagagaaat gatcaaattt agtttccgaa caacacgaac   3300

accaagcttg ctgctttttg tgagctcctt ttacaaagaa tacctttctg tgatcattgc   3360

caaaaatgga agtttgcaga tcaggtacaa gttaaataaa tatcaagagc ctgatgttgt   3420

taactttgat tttaaaaaca tggctgatgg acaacttcac cacataatga ttaacagaga   3480

agaaggagtg gtctttatag agattgacga taatagaagg agacaagttc acctgtcatc   3540

aggcacagaa ttcagtgcag tcaaatctct ggtattgggc aggattttag aacacagtga   3600

tgtggaccag gatactgcac tggcaggtgc gcagggcttc acaggctgcc tctctgcagt   3660

gcagctcagc cacgtggccc ctctgaaggc agctctgcac cccagccacc cagaccctgt   3720

cactgttaca ggacacgtga ctgagtccag ctgtatggcc cagcctggca ctgatgccac   3780

atcaagggaa aggacacact cgtttgcaga tcattctgga acaatagatg acagagagcc   3840

ccttgctaat gcaatcaaaa gtgactctgc agtaattgga ggtctgatag ctgttgtgat   3900

ttttatcttg ctttgcatca ctgccatagc tgttcgcatt tatcagcaga aaaggttata   3960

taaaagaagt gaggcaaaaa ggtcagagaa tgtagacagt gctgaggctg ttctgaaaag   4020

tgagcttaat atacaaaatg cagtcaatga aaatcagaaa gagtacttct tctgattggc   4080

agctatgatt taacataaaa ttatgatagt ttgttttaat agccaggggt tctcaatgga   4140

aaaacgaatg ctcttacact gaatgtacag gcagtgggct tgcagcactg ccatcttgcc   4200

atgtacaggc ttggggtggc tccaggaagc ctcgtccagt gatatatttc tcatagcatt   4260

cattctatgg aacaagaaat tagatattgc tgttaatttt caactgttct ggtatgatct   4320

aaaacaagtt taacctgctt aatggctaca gtttttacat gtgaaaactg tagccttggt   4380

ctcttaacca tgtaatacat aagttttgtt agaggtaaaa attaaatttg gactataatg   4440

tccttgcttt atttgagaac atttgctgtg tttgcttttg tctcctcgtg gtgttattca   4500

tagacctgga aatgcttctc agatcctgtg tggccggtgt ttgcatcttc agtggccaca   4560

agcataataa agcccctttg cctttctctg tattatattc aatacaatac atcaatagtc   4620

ttgaaaaatg ttttgctgtc tttgctttgt ttgtatt                            4657


<210>  8938
<211>  1311
<212>  PRT
<213>  Homo sapiens

<400>  8938

Met Leu Leu Phe Tyr Leu Leu Val Val Leu Ser Ile Asp Ser Thr Lys 
1               5                   10                  15


Ala Ser Ala Leu Thr Asn Pro Asn Val Ala Leu Phe Leu Leu Ala Asp 
            20                  25                  30


Asp Cys Asp Asp Pro Leu Val Ser Ala Leu Pro Gln Ala Ser Phe Ser 
        35                  40                  45


Ser Ser Ser Glu Leu Ser Ser Ser His Gly Pro Gly Phe Ala Arg Leu 
    50                  55                  60


Asn Arg Arg Asp Gly Ala Gly Gly Trp Ser Pro Leu Val Ser Asn Lys 
65                  70                  75                  80


Tyr Gln Trp Leu Gln Ile Asp Leu Gly Glu Arg Met Glu Val Thr Ala 
                85                  90                  95


Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn Trp Val Thr Ser Tyr 
            100                 105                 110


Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp Lys Gln Tyr Arg Gln 
        115                 120                 125


Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala Asn Ala Asp Ser Val 
    130                 135                 140


Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala Arg Phe Leu Arg Phe 
145                 150                 155                 160


Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile Gly Met Arg Ile Glu 
                165                 170                 175


Val Phe Gly Cys Ala Tyr Arg Ser Glu Val Val Asp Leu Asp Gly Lys 
            180                 185                 190


Ser Ser Leu Leu Tyr Arg Phe Asp Gln Lys Ser Leu Ser Pro Ile Lys 
        195                 200                 205


Asp Ile Ile Ser Leu Lys Phe Lys Thr Met Gln Ser Asp Gly Ile Leu 
    210                 215                 220


Leu His Arg Glu Gly Pro Asn Gly Asp His Ile Thr Leu Gln Leu Arg 
225                 230                 235                 240


Arg Ala Arg Leu Phe Leu Leu Ile Asn Ser Gly Glu Ala Lys Leu Pro 
                245                 250                 255


Ser Thr Ser Thr Leu Val Asn Leu Thr Leu Gly Ser Leu Leu Asp Asp 
            260                 265                 270


Gln His Trp His Ser Val Leu Ile Gln Arg Leu Gly Lys Gln Val Asn 
        275                 280                 285


Phe Thr Val Asp Glu His Arg His His Phe His Ala Arg Gly Glu Phe 
    290                 295                 300


Asn Leu Met Asn Leu Asp Tyr Glu Ile Ser Phe Gly Gly Ile Pro Ala 
305                 310                 315                 320


Pro Gly Lys Ser Val Ser Phe Pro His Arg Asn Phe His Gly Cys Leu 
                325                 330                 335


Glu Asn Leu Tyr Tyr Asn Gly Val Asp Ile Ile Asp Leu Ala Lys Gln 
            340                 345                 350


Gln Lys Pro Gln Ile Ile Ala Met Gly Asn Val Ser Phe Ser Cys Ser 
        355                 360                 365


Gln Pro Gln Ser Met Pro Val Thr Phe Leu Ser Ser Arg Ser Tyr Leu 
    370                 375                 380


Ala Leu Pro Asp Phe Ser Gly Glu Glu Glu Val Ser Ala Thr Phe Gln 
385                 390                 395                 400


Phe Arg Thr Trp Asn Lys Ala Gly Leu Leu Leu Phe Ser Glu Leu Gln 
                405                 410                 415


Leu Ile Ser Gly Gly Ile Leu Leu Phe Leu Ser Asp Gly Lys Leu Lys 
            420                 425                 430


Ser Asn Leu Tyr Gln Pro Gly Lys Leu Pro Ser Asp Ile Thr Ala Gly 
        435                 440                 445


Val Glu Leu Asn Asp Gly Gln Trp His Ser Val Ser Leu Ser Ala Lys 
    450                 455                 460


Lys Asn His Leu Ser Val Ala Val Asp Gly Gln Met Ala Ser Ala Ala 
465                 470                 475                 480


Pro Leu Leu Gly Pro Glu Gln Ile Tyr Ser Gly Gly Thr Tyr Tyr Phe 
                485                 490                 495


Gly Gly Cys Pro Asp Lys Ser Phe Gly Ser Lys Cys Lys Ser Pro Leu 
            500                 505                 510


Gly Gly Phe Gln Gly Cys Met Arg Leu Ile Ser Ile Ser Gly Lys Val 
        515                 520                 525


Val Asp Leu Ile Ser Val Gln Gln Gly Ser Leu Gly Asn Phe Ser Asp 
    530                 535                 540


Leu Gln Ile Asp Ser Cys Gly Ile Ser Asp Arg Cys Leu Pro Asn Tyr 
545                 550                 555                 560


Cys Glu His Gly Gly Glu Cys Ser Gln Ser Trp Ser Thr Phe His Cys 
                565                 570                 575


Asn Cys Thr Asn Thr Gly Tyr Arg Gly Ala Thr Cys His Asn Ser Ile 
            580                 585                 590


Tyr Glu Gln Ser Cys Glu Ala Tyr Lys His Arg Gly Asn Thr Ser Gly 
        595                 600                 605


Phe Tyr Tyr Ile Asp Ser Asp Gly Ser Gly Pro Leu Glu Pro Phe Leu 
    610                 615                 620


Leu Tyr Cys Asn Met Thr Glu Thr Ala Trp Thr Ile Ile Gln His Asn 
625                 630                 635                 640


Gly Ser Asp Leu Thr Arg Val Arg Asn Thr Asn Pro Glu Asn Pro Tyr 
                645                 650                 655


Ala Gly Phe Phe Glu Tyr Val Ala Ser Met Glu Gln Leu Gln Ala Thr 
            660                 665                 670


Ile Asn Arg Ala Glu His Cys Glu Gln Glu Phe Thr Tyr Tyr Cys Lys 
        675                 680                 685


Lys Ser Arg Leu Val Asn Lys Gln Asp Gly Thr Pro Leu Ser Trp Trp 
    690                 695                 700


Val Gly Arg Thr Asn Glu Thr Gln Thr Tyr Trp Gly Gly Ser Ser Pro 
705                 710                 715                 720


Asp Leu Gln Lys Cys Thr Cys Gly Leu Glu Gly Asn Cys Ile Asp Ser 
                725                 730                 735


Gln Tyr Tyr Cys Asn Cys Asp Ala Asp Arg Asn Glu Trp Thr Asn Asp 
            740                 745                 750


Thr Gly Leu Leu Ala Tyr Lys Glu His Leu Pro Val Thr Lys Ile Val 
        755                 760                 765


Ile Thr Asp Thr Gly Arg Leu His Ser Glu Ala Ala Tyr Lys Leu Gly 
    770                 775                 780


Pro Leu Leu Cys Gln Gly Asp Arg Ser Phe Trp Asn Ser Ala Ser Phe 
785                 790                 795                 800


Asp Thr Glu Ala Ser Tyr Leu His Phe Pro Thr Phe His Gly Glu Leu 
                805                 810                 815


Ser Ala Asp Val Ser Phe Phe Phe Lys Thr Thr Ala Ser Ser Gly Val 
            820                 825                 830


Phe Leu Glu Asn Leu Gly Ile Ala Asp Phe Ile Arg Ile Glu Leu Arg 
        835                 840                 845


Ser Pro Thr Val Val Thr Phe Ser Phe Asp Val Gly Asn Gly Pro Phe 
    850                 855                 860


Glu Ile Ser Val Gln Ser Pro Thr His Phe Asn Asp Asn Gln Trp His 
865                 870                 875                 880


His Val Arg Val Glu Arg Asn Met Lys Glu Ala Ser Leu Gln Val Asp 
                885                 890                 895


Gln Leu Thr Pro Lys Thr Gln Pro Ala Pro Ala Asp Gly His Val Leu 
            900                 905                 910


Leu Gln Leu Asn Ser Gln Leu Phe Val Gly Gly Thr Ala Thr Arg Gln 
        915                 920                 925


Arg Gly Phe Leu Gly Cys Ile Arg Ser Leu Gln Leu Asn Gly Met Thr 
    930                 935                 940


Leu Asp Leu Glu Glu Arg Ala Gln Val Thr Pro Glu Val Gln Pro Gly 
945                 950                 955                 960


Cys Arg Gly His Cys Ser Ser Tyr Gly Lys Leu Cys Arg Asn Gly Gly 
                965                 970                 975


Lys Cys Arg Glu Arg Pro Ile Gly Phe Phe Cys Asp Cys Thr Phe Ser 
            980                 985                 990


Ala Tyr Thr Gly Pro Phe Cys Ser Asn Glu Ile Ser Ala Tyr Phe Gly 
        995                 1000                1005


Ser Gly Ser Ser Val Ile Tyr Asn Phe Gln Glu Asn Tyr Leu Leu Ser 
    1010                1015                1020


Lys Asn Ser Ser Ser His Ala Ala Ser Phe His Gly Asp Met Lys Leu 
1025                1030                1035                1040


Ser Arg Glu Met Ile Lys Phe Ser Phe Arg Thr Thr Arg Thr Pro Ser 
                1045                1050                1055


Leu Leu Leu Phe Val Ser Ser Phe Tyr Lys Glu Tyr Leu Ser Val Ile 
            1060                1065                1070


Ile Ala Lys Asn Gly Ser Leu Gln Ile Arg Tyr Lys Leu Asn Lys Tyr 
        1075                1080                1085


Gln Glu Pro Asp Val Val Asn Phe Asp Phe Lys Asn Met Ala Asp Gly 
    1090                1095                1100


Gln Leu His His Ile Met Ile Asn Arg Glu Glu Gly Val Val Phe Ile 
1105                1110                1115                1120


Glu Ile Asp Asp Asn Arg Arg Arg Gln Val His Leu Ser Ser Gly Thr 
                1125                1130                1135


Glu Phe Ser Ala Val Lys Ser Leu Val Leu Gly Arg Ile Leu Glu His 
            1140                1145                1150


Ser Asp Val Asp Gln Asp Thr Ala Leu Ala Gly Ala Gln Gly Phe Thr 
        1155                1160                1165


Gly Cys Leu Ser Ala Val Gln Leu Ser His Val Ala Pro Leu Lys Ala 
    1170                1175                1180


Ala Leu His Pro Ser His Pro Asp Pro Val Thr Val Thr Gly His Val 
1185                1190                1195                1200


Thr Glu Ser Ser Cys Met Ala Gln Pro Gly Thr Asp Ala Thr Ser Arg 
                1205                1210                1215


Glu Arg Thr His Ser Phe Ala Asp His Ser Gly Thr Ile Asp Asp Arg 
            1220                1225                1230


Glu Pro Leu Ala Asn Ala Ile Lys Ser Asp Ser Ala Val Ile Gly Gly 
        1235                1240                1245


Leu Ile Ala Val Val Ile Phe Ile Leu Leu Cys Ile Thr Ala Ile Ala 
    1250                1255                1260


Val Arg Ile Tyr Gln Gln Lys Arg Leu Tyr Lys Arg Ser Glu Ala Lys 
1265                1270                1275                1280


Arg Ser Glu Asn Val Asp Ser Ala Glu Ala Val Leu Lys Ser Glu Leu 
                1285                1290                1295


Asn Ile Gln Asn Ala Val Asn Glu Asn Gln Lys Glu Tyr Phe Phe 
            1300                1305                1310


<210>  8939
<211>  417
<212>  DNA
<213>  Homo sapiens

<400>  8939
caatatgccc catttcgcta acctccactg agccccaagc tctgaagatc aaagtcaaag     60

cacgaaatga acgtgagaga gctggaaagc taactacaaa gcctctaaaa gttacgtaac    120

atgaagaaac acactcgatt ctgcctctcc cattgaatag agcaataaaa catggacaca    180

acacacaaag cagctatttg aggactctga gaaggaaatg gcagcacaca gattggggga    240

gaagaccaga atttgaaatg ctgctgaacc acagtagagt gatacaagat gtgaccgttg    300

aagaatgctg gatgaaaggc gactgccttc atggaacccg tatggactcc gtgtatattt    360

tttgggtaat ttcctatgac tcagtaatta tttcaaaata aaaatgttta aaaagtg       417


<210>  8940
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  8940

Met Leu Leu Asn His Ser Arg Val Ile Gln Asp Val Thr Val Glu Glu 
1               5                   10                  15


Cys Trp Met Lys Gly Asp Cys Leu His Gly Thr Arg Met Asp Ser Val 
            20                  25                  30


Tyr Ile Phe Trp Val Ile Ser Tyr Asp Ser Val Ile Ile Ser Lys 
        35                  40                  45


<210>  8941
<211>  833
<212>  DNA
<213>  Homo sapiens

<400>  8941
ttggacatca gctggggctg gagtcacctg caggctggcc tggggtcggg cagggggatc     60

tgcttccaag gctctgcttc agaggcggct ccctcccacg gtaggcgcat ggtttcctgt    120

ctccaaagtg ggcctctgca caaggctgct tggatgacct catgatatgg tggctgctga    180

ccagggtaga ggctggaacc ccttggatgg cccaacctgg gaggtactag ccatgcctct    240

gccattgggc ccggccacac aggttcctgc cctcttctcc gctgcccttg tgcctcccgt    300

gtcctcgctg cgtcctaacc aaatgctgga ctggcagaga ctgaaaacgc cccacggggc    360

ccctgtggct tgctcactcg ggctctccgg agagtgggtg ccaaccccct gcgccctgag    420

catcttggct ctgcttggct tgcagctgga tccccttttt ggactttggg gctgcacacg    480

caccttgttc tggagcgaat gggctcgtga gagccgcagg ccctgaggca tggcctaact    540

caggcagagt agttggcgaa ggccccagag ggacccaggc tatcgtcctg cagctgccgg    600

ccagtccatt tggttaaact cacgagagtg tgtgcttgtc gatgtagctg attctgtatg    660

ggtggggatt tggaccagcc cttcatgctt aatccaaaac accttccgcc tcccagagct    720

tgtggctttg atgccatttg tctgaacatc acaaggaacc acgtgggaaa acaggacttc    780

gtggcgtgcc ctggcagaca agccaaagca actgtgggca tcaggctgtg ggg           833


<210>  8942
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  8942

Met Gly Gly Asp Leu Asp Gln Pro Phe Met Leu Asn Pro Lys His Leu 
1               5                   10                  15


Pro Pro Pro Arg Ala Cys Gly Phe Asp Ala Ile Cys Leu Asn Ile Thr 
            20                  25                  30


Arg Asn His Val Gly Lys Gln Asp Phe Val Ala Cys Pro Gly Arg Gln 
        35                  40                  45


Ala Lys Ala Thr Val Gly Ile Arg Leu 
    50                  55


<210>  8943
<211>  1508
<212>  DNA
<213>  Homo sapiens

<400>  8943
aaaccacaga cctcctttct ggaaacatct gggtcgggac tccccaccga ggggtcatag     60

accctcactt ccagggtgtg ccctgacctc agcatgactg gggctggggc atatcctgga    120

gccccagata ggaacccaac cagagtgacc gcggcaagca gggcagtggg tcccatggaa    180

aactccgcct ccgcttcccg ttgcttggcc acctgtcctc aatgccgggc accccactag    240

gcctccgggc tgggcaacaa cggccagagg gatggtcact aaacccgttt cctcgctctg    300

gacacatggc taagcaacat tttcaccccc tcgctgcagg cgggggccac aggactggct    360

ccagtcagcg caatgtaggt cgaggtgacg tcacctctgt gccatcctct gctcatcact    420

agcagtgggg aggccgaggc tccgggaaac cggaccccga gtcaccttgt ggaagaccca    480

ctgagcaccc cgttggaccc gattgaagga gaatgcgctt cggctgcatc acgccactga    540

agacgcaggg ttacttgtga cagccgctga cctcacccac cctgcccagc acaccgcacc    600

tcgacaaggc caaggccaag aattgacctc ctggagctca tcacgttctc agcgtgagac    660

tggaagcgga agccgagagg caggaggtga aaatgcctgg tgcagagcgg ctgctccaaa    720

gtggaaccct ggcagacgaa aggacacaca aaacgtggtc ggaccactcc atggactatt    780

cctcggcgag agaggaatga ggcactgaca ccccctgcaa cgcagtagac cctgacgacg    840

ctgctgagtg aaagcagcca gacaccaaag gccgcagtgt gtgagccccc cagcctgtga    900

gccagaggct gaaccagttg agggacaaag accagcccgg cctgggttcc tcatcgggcg    960

actgccccag gaccttgcca tgtccttcac cagcaaacgg tgggtgcctc ctgcagatgc   1020

tgacagctcc accctcccca cctccaagat ttgctggggc tgaaatgccc cccaccccca   1080

gattccaatg acccagcaca aatgccgcct ctcccaggaa gcctgcctgg accccatgga   1140

agaaaacatc ccactcgctg atcatacgaa ctcgtctgac tttaaacttc ccaaagctgc   1200

ccacgatgac tgttgcagct ccgaccggcc cactcttaat ttattttcac agtccccagt   1260

cctccgggcc agccgcacta caataaccta ttgttaacat ggaagtctcc ccatgtggga   1320

acggacattt ggaagaccat cctttgaacg gacaccaggc tcaccaagtc cttgattcag   1380

taacacggac tgcggcagca atttgagggg agatgaggca ccagccgggc acaaagacac   1440

agacaccccc tttttatttg tcacagctga gttgtcatac attccctcga ataaatgttc   1500

ccatctgg                                                            1508


<210>  8944
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  8944

Met Thr Gln His Lys Cys Arg Leu Ser Gln Glu Ala Cys Leu Asp Pro 
1               5                   10                  15


Met Glu Glu Asn Ile Pro Leu Ala Asp His Thr Asn Ser Ser Asp Phe 
            20                  25                  30


Lys Leu Pro Lys Ala Ala His Asp Asp Cys Cys Ser Ser Asp Arg Pro 
        35                  40                  45


Thr Leu Asn Leu Phe Ser Gln Ser Pro Val Leu Arg Ala Ser Arg Thr 
    50                  55                  60


Thr Ile Thr Tyr Cys 
65


<210>  8945
<211>  577
<212>  DNA
<213>  Homo sapiens

<400>  8945
tttcaccagc ggccggggag gaggcatcac tgctgccatc cccattgcac agagggcgcc     60

tcgaagcatg gggaggcatc atgctgggtt ggcattgctc ccgagacttc aggtccacca    120

cagactcagc acatgacctc ctttggaaag tgggtctttg agatgtaatt atgaccagat    180

gaggtcatgc tgggttaagg tgggtcccca tccaaagact ggtgtcctcc gtagaaggcc    240

gcgtgaagac acacagagaa ggtcacatga tggcagaggc agcgatcaca gcgatgaagt    300

tcagtgatcg gagagatggc ttctaggagc caaggaaccc caaggactgt gggcaatgcc    360

agaaactgga agaaaggccc ggacagattc ccactctagc tccagcagaa ggaagccgtc    420

ccgctgacac cctgattccg gacttcggat ctccagaact gagcccccca gcctgtgagc    480

cagaggctga accagttgag ggacaaagac cagcccggcc tgggttcctc atcgggcgac    540

tgccccagga ccttgccatg tccttcacca gcaaacg                             577


<210>  8946
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  8946

Met Arg Ser Cys Trp Val Lys Val Gly Pro His Pro Lys Thr Gly Val 
1               5                   10                  15


Leu Arg Arg Arg Pro Arg Glu Asp Thr Gln Arg Arg Ser His Asp Gly 
            20                  25                  30


Arg Gly Ser Asp His Ser Asp Glu Val Gln 
        35                  40


<210>  8947
<211>  656
<212>  DNA
<213>  Homo sapiens

<400>  8947
agaatccgga aacaaagcct cggggaagaa ccgcacctga cctccctcct gcctggtgga     60

agctgtccac gctgccggca cagcccccgg agggaaataa ccaagcccgc ccctgaggat    120

ctagaacctg ctatcagctt cacagctgaa tccaaattcc caaactccca agtactggtg    180

tacagtgaag gattaactga actcacagaa agtctgacct ttcccccggc tcctggggcg    240

gtcacctcta ggcccttgaa gagtcccgcc tgatgagagt gtctttgttt acctgagggc    300

ttagccaccc tgaacagcct atgctaatga taagattcat ggtggggcct tgaaccacag    360

ggcatcagct tgacgtgcgg aggtgctgga ggttaaggtc agtcacatgg tgtcagccgt    420

gcccacgtga ccaaggccca gcaaagactc tggacaccga ggctggcgga gcgtccctgg    480

ttggcaatgc tgtgtgccat cacacgctgt tgtcatgagg agttaacact gtccaggact    540

ccacggagag ggacagctcg aagctctgtg ctgggaaccc tcctgggctc accccatggg    600

tccctcccct tggctgactt aaacctgcat ctgtaataaa ctataactgt gagtgc        656


<210>  8948
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  8948

Met Leu Cys Ala Ile Thr Arg Cys Cys His Glu Glu Leu Thr Leu Ser 
1               5                   10                  15


Arg Thr Pro Arg Arg Gly Thr Ala Arg Ser Ser Val Leu Gly Thr Leu 
            20                  25                  30


Leu Gly Ser Pro His Gly Ser Leu Pro Leu Ala Asp Leu Asn Leu His 
        35                  40                  45


Leu 



<210>  8949
<211>  579
<212>  DNA
<213>  Homo sapiens

<400>  8949
caccactgtc tgctgagctg tgtgtgtcag aaacagaggg aaccaggtgc cagtccctcc     60

cctggcctag ctcttcccac taccatgact cttgttggga gtgaaaggat tttaccccct    120

ttctttgtca gcagctggcc tggactccca ggggagcctg gtcaatatta atggacacgc    180

aaggctgtgg ggcacacagg gttttgtgat tatggattat ctcctgctca gcaccatctt    240

gaaggtggag acaaaagttc tcagccaggg ccaggaattc caagcccaca gtgggtctgg    300

atttaaagta ctattgtgcc tgggcctgtg atgtcagcat cccccactcc cagggggccc    360

tggagaacat ggcatctcag agcagttcaa ggggctcaag cagactgggc ctcggaggac    420

tggccaggct gggaaaatgc cattgtttcc tgaatttccc tggaccgcag ccaccacctt    480

taaagcttta gttagttaat ggggaaggat gaaaggggga aatttaatag ggttcttcca    540

aataaatggg gattcacagc ccaccgctga atagcctaa                           579


<210>  8950
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  8950

Met Asp Tyr Leu Leu Leu Ser Thr Ile Leu Lys Val Glu Thr Lys Val 
1               5                   10                  15


Leu Ser Gln Gly Gln Glu Phe Gln Ala His Ser Gly Ser Gly Phe Lys 
            20                  25                  30


Val Leu Leu Cys Leu Gly Leu 
        35


<210>  8951
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  8951
cctgttccca ggatggcctg gagcagagcc agcccagaga tggggagaga agaaaaccag     60

ccagcgcccc gcagaagggc tgcgtgagga gtcccggcgg cctgagtccc cccagcctgc    120

agagcccaca gccctgtccc ccggctggtg ctgagccgtc tcctgcgggc ggtgtgtccc    180

caaggcaagg cagagtgcat ggcacgtgta tctcctcgca tggaccctgc ctggaacatg    240

tggtctctgc tggcccaggc ttgtcacggt actaaatctg gagactgagc cctctgcctc    300

tgtctgcccc ccgccgctgc ctccagcttc tggagctgtc atgttgagtt cacgaggttc    360

caaagtcacc ttccatgcag ggagccttcg ggttctgact cagcctgggg cctccccgga    420

gcaccagggt gcgggaggca ccacctgcca tctggccccc tctggaggac gcgcgtcagc    480

ctcacacctg catcgccttt gccccgcttc cctggggact ggtggccctg ggctgtggga    540

ctgcaatgtg gaggaaggcg cacatcccct gctgccctcc tgaaggtctg atttaaattc    600

aggagcttcc cctgggatcc tcctcctcca gcccgcatag aaggaggtgt gaggctt       657


<210>  8952
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  8952

Met Leu Ser Ser Arg Gly Ser Lys Val Thr Phe His Ala Gly Ser Leu 
1               5                   10                  15


Arg Val Leu Thr Gln Pro Gly Ala Ser Pro Glu His Gln Gly Ala Gly 
            20                  25                  30


Gly Thr Thr Cys His Leu Ala Pro Ser Gly Gly Arg Ala Ser Ala Ser 
        35                  40                  45


His Leu His Arg Leu Cys Pro Ala Ser Leu Gly Thr Gly Gly Pro Gly 
    50                  55                  60


Leu Trp Asp Cys Asn Val Glu Glu Gly Ala His Pro Leu Leu Pro Ser 
65                  70                  75                  80


<210>  8953
<211>  2152
<212>  DNA
<213>  Homo sapiens

<400>  8953
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatgtg actactgtga agactggcca gaggcacaga ggatctcagc ctcgctcctg    960

gacagccggt cctacgagac gctcgtggat ttcgataacc acctggatga cattcggaat   1020

gactggacaa acccagagat caataaagct gtcctacact tgtgctaggc aggcaccgct   1080

gtgactgggc tccgggcctt tccactacgt tgaagaagaa aacctatttt taaatgtaaa   1140

taaaatatct tgtagcctgt gtggaaagct gaccgtttta agaagtggca tgtgccttga   1200

aagggggcag aatgttcagt cggtcgtgtt tttaacacag agtctctaga agaggtgcag   1260

acatcccgtc tgactgtccc tgtggactct ctcagttgta tgttgctata atcctccaaa   1320

tcaaagctct ttctgcttgt gcaagattgt tcctattaaa cagttttaac taacctttta   1380

taatctggag agaatacttt ttaaggcttt tgaactatct ttttttaaaa aaaaaaaaaa   1440

aagcccacat cttatactcc aatgagtgtg tttgtgagtt tttatcctgt ttgaattttg   1500

atgtcgtcca ggcgtcctgg gatcagggta gacacgtgga gtgctggtgc tgagctgttt   1560

gagaagctct gtgtgggtgt ttctgtggtc aggtaggctg ggctgtgaac agcactgctc   1620

cacatggtgt cggctcacag agccaccgca actctgccca gcgggagtga caccactgat   1680

gccacagaag cctttatcgt taggggcaaa agcagacatc tctggtagca ggagctcagt   1740

gtggtgctct tcagccacgc agaaagctca cgtgcctgca gggccaggaa agggaaatga   1800

tcgtttcttt tgtattagga aaaacaagac ttagacttcc cgagttgtgc agagtgacgt   1860

ctgtactttt tatacttaga acatttggtc aagttttgta accaaacctt agggaattga   1920

gagggaaact ttatggtacg tttacctttt ttccttttta tatgaattat tttgtacaaa   1980

gttcagagag cggtaccttt cctactgtct tttctttgac tccatggagg aatttgtaac   2040

gatcggtgtg acctgaaagg gtttgtgata cagcggtcac tattttctct taacacatag   2100

gaaaaaagtt cagacatcgc tacaataaat gtgctttatt tgatccacca aa           2152


<210>  8954
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  8954

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met 
        115                 120                 125


<210>  8955
<211>  2247
<212>  DNA
<213>  Homo sapiens

<400>  8955
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatggt agacaacacc aagtttacga tggactgcgt agcgcctacg atccacgtgt    960

acgagcacca tgagaacaga tggcggtgca gagacccaca ccatgactac tgtgaagact   1020

ggccagaggc acagaggatc tcagcctcgc tcctggacag ccggtcctac gagacgctcg   1080

tggatttcga taaccacctg gatgacattc ggaatgactg gacaaaccca gagatcaata   1140

aagctgtcct acacttgtgc taggcaggca ccgctgtgac tgggctccgg gcctttccac   1200

tacgttgaag aagaaaacct atttttaaat gtaaataaaa tatcttgtag cctgtgtgga   1260

aagctgaccg ttttaagaag tggcatgtgc cttgaaaggg ggcagaatgt tcagtcggtc   1320

gtgtttttaa cacagagtct ctagaagagg tgcagacatc ccgtctgact gtccctgtgg   1380

actctctcag ttgtatgttg ctataatcct ccaaatcaaa gctctttctg cttgtgcaag   1440

attgttccta ttaaacagtt ttaactaacc ttttataatc tggagagaat actttttaag   1500

gcttttgaac tatctttttt taaaaaaaaa aaaaaaagcc cacatcttat actccaatga   1560

gtgtgtttgt gagtttttat cctgtttgaa ttttgatgtc gtccaggcgt cctgggatca   1620

gggtagacac gtggagtgct ggtgctgagc tgtttgagaa gctctgtgtg ggtgtttctg   1680

tggtcaggta ggctgggctg tgaacagcac tgctccacat ggtgtcggct cacagagcca   1740

ccgcaactct gcccagcggg agtgacacca ctgatgccac agaagccttt atcgttaggg   1800

gcaaaagcag acatctctgg tagcaggagc tcagtgtggt gctcttcagc cacgcagaaa   1860

gctcacgtgc ctgcagggcc aggaaaggga aatgatcgtt tcttttgtat taggaaaaac   1920

aagacttaga cttcccgagt tgtgcagagt gacgtctgta ctttttatac ttagaacatt   1980

tggtcaagtt ttgtaaccaa accttaggga attgagaggg aaactttatg gtacgtttac   2040

cttttttcct ttttatatga attattttgt acaaagttca gagagcggta cctttcctac   2100

tgtcttttct ttgactccat ggaggaattt gtaacgatcg gtgtgacctg aaagggtttg   2160

tgatacagcg gtcactattt tctcttaaca cataggaaaa aagttcagac atcgctacaa   2220

taaatgtgct ttatttgatc caccaaa                                       2247


<210>  8956
<211>  210
<212>  PRT
<213>  Homo sapiens

<400>  8956

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met Val Asp 
        115                 120                 125


Asn Thr Lys Phe Thr Met Asp Cys Val Ala Pro Thr Ile His Val Tyr 
    130                 135                 140


Glu His His Glu Asn Arg Trp Arg Cys Arg Asp Pro His His Asp Tyr 
145                 150                 155                 160


Cys Glu Asp Trp Pro Glu Ala Gln Arg Ile Ser Ala Ser Leu Leu Asp 
                165                 170                 175


Ser Arg Ser Tyr Glu Thr Leu Val Asp Phe Asp Asn His Leu Asp Asp 
            180                 185                 190


Ile Arg Asn Asp Trp Thr Asn Pro Glu Ile Asn Lys Ala Val Leu His 
        195                 200                 205


Leu Cys 
    210


<210>  8957
<211>  1555
<212>  DNA
<213>  Homo sapiens

<400>  8957
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatggt agacaacacc aagtttacga tggactgcgt agcgcctacg atccacgtgt    960

acgagcacca tgagaacaga tggcggtgca gagacccaca ccatgactac tgtgaagact   1020

ggccagaggc acagaggatc tcagcctcgc tcctggacag ccggtcctac gagacgctcg   1080

tggatttcga taaccacctg gatgacattc ggaatgactg gacaaaccca gagatcaata   1140

aagctgtcct acacttgtgc taggcaggca ccgctgtgac tgggctccgg gcctttccac   1200

tacgttgaag aagaaaacct atttttaaat gtaaataaaa tatcttgtag cctgtgtgga   1260

aagctgaccg ttttaagaag tggcatgtgc cttgaaaggg ggcagaatgt tcagtcggtc   1320

gtgtttttaa cacagagtct ctagaagagg tgcagacatc ccgtctgact gtccctgtgg   1380

actctctcag ttgtatgttg ctataatcct ccaaatcaaa gctctttctg cttgtgcaag   1440

attgttccta ttaaacagtt ttaactaacc ttttataatc tggagagaat actttttaag   1500

gcttttgaac tatctttttt taaaaaaaaa aaaaaaagcc cacatcttat actcc        1555


<210>  8958
<211>  210
<212>  PRT
<213>  Homo sapiens

<400>  8958

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met Val Asp 
        115                 120                 125


Asn Thr Lys Phe Thr Met Asp Cys Val Ala Pro Thr Ile His Val Tyr 
    130                 135                 140


Glu His His Glu Asn Arg Trp Arg Cys Arg Asp Pro His His Asp Tyr 
145                 150                 155                 160


Cys Glu Asp Trp Pro Glu Ala Gln Arg Ile Ser Ala Ser Leu Leu Asp 
                165                 170                 175


Ser Arg Ser Tyr Glu Thr Leu Val Asp Phe Asp Asn His Leu Asp Asp 
            180                 185                 190


Ile Arg Asn Asp Trp Thr Asn Pro Glu Ile Asn Lys Ala Val Leu His 
        195                 200                 205


Leu Cys 
    210


<210>  8959
<211>  1460
<212>  DNA
<213>  Homo sapiens

<400>  8959
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatgtg actactgtga agactggcca gaggcacaga ggatctcagc ctcgctcctg    960

gacagccggt cctacgagac gctcgtggat ttcgataacc acctggatga cattcggaat   1020

gactggacaa acccagagat caataaagct gtcctacact tgtgctaggc aggcaccgct   1080

gtgactgggc tccgggcctt tccactacgt tgaagaagaa aacctatttt taaatgtaaa   1140

taaaatatct tgtagcctgt gtggaaagct gaccgtttta agaagtggca tgtgccttga   1200

aagggggcag aatgttcagt cggtcgtgtt tttaacacag agtctctaga agaggtgcag   1260

acatcccgtc tgactgtccc tgtggactct ctcagttgta tgttgctata atcctccaaa   1320

tcaaagctct ttctgcttgt gcaagattgt tcctattaaa cagttttaac taacctttta   1380

taatctggag agaatacttt ttaaggcttt tgaactatct ttttttaaaa aaaaaaaaaa   1440

aagcccacat cttatactcc                                               1460


<210>  8960
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  8960

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met 
        115                 120                 125


<210>  8961
<211>  1379
<212>  DNA
<213>  Homo sapiens

<400>  8961
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatgtg actactgtga agactggcca gaggcacaga ggatctcagc ctcgctcctg    960

gacagccggt cctacgagac gctcgtggat ttcgataacc acctggatga cattcggaat   1020

gactggacaa acccagagat caataaagct gtcctacact tgtgctaggc aggcaccgct   1080

gtgactgggc tccgggcctt tccactacgt tgaagaagaa aacctatttt taaatgtaaa   1140

taaaatatct tgtagcctgt gtggaaagct gaccgtttta agaagtggca tgtgccttga   1200

aagggggcag aatgttcagt cggtcgtgtt tttaacacag agtctctaga agaggtgcag   1260

acatcccgtc tgactgtccc tgtggactct ctcagttgta tgttgctata atcctccaaa   1320

tcaaagctct ttctgcttgt gcaagattgt tcctattaaa cagttttaac taacctttt    1379


<210>  8962
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  8962

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met 
        115                 120                 125


<210>  8963
<211>  1474
<212>  DNA
<213>  Homo sapiens

<400>  8963
gcagacttga tggctcccgg ccccccgacc cggcccggcc tggcggcgcc gcaccggcca     60

cctcctgtct cacctgccgc cactgcccgc cgcgaccgcc ctctacaccc ggtgtcccgc    120

gaccggaaga gagcaaggcc gcgccgcgga gcaccacggg atcgaggaag actccgcccg    180

cacccggccg cacggaggtc accgtggagc ggaaaagggt agcgctgcga acgtcgtaaa    240

atgccgggcc gggctgcttt ccggcaggcg ttggagaggc tgctttccgg cggcgccggg    300

cgagaagcgc gactggagtc tggggctgcg gcttcccaga ggcgcgagtc gcttttccag    360

gagccgaggc ccaaacgggg ccgggcctga agggtccccc gccagcccgc ggccgcgcca    420

tcaatcgccg ccgcctcgtc ccgcttctcg gctgaggcgc cgcgcggcca ggcagcgggt    480

ccaggcctca gccgcgcgcc caggggcctc cggggccctc ccgggtcagc atgcccgggg    540

tgaaactgac cacccaggcc tactgcaaga tggtgctgca cggcgccaag tacccgcact    600

gcgccgtcaa cgggctcctg gtggccgaga agcagaagcc gcgtaaggag cacctccccc    660

tgggcggccc cggcgcccac cacaccctct tcgtggactg catccccctc ttccacggca    720

ccctggccct cgcccccatg ctggaggtgg ctctcaccct gattgattca tggtgcaaag    780

atcatagcta cgtgattgct ggttattatc aagctaatga gcgagtaaag gatgccagtc    840

caaaccaggt tgcagagaag gtggcctcca gaatcgccga gggcttcagc gacactgcgc    900

tcatcatggt agacaacacc aagtttacga tggactgcgt agcgcctacg atccacgtgt    960

acgagcacca tgagaacaga tggcggtgca gagacccaca ccatgactac tgtgaagact   1020

ggccagaggc acagaggatc tcagcctcgc tcctggacag ccggtcctac gagacgctcg   1080

tggatttcga taaccacctg gatgacattc ggaatgactg gacaaaccca gagatcaata   1140

aagctgtcct acacttgtgc taggcaggca ccgctgtgac tgggctccgg gcctttccac   1200

tacgttgaag aagaaaacct atttttaaat gtaaataaaa tatcttgtag cctgtgtgga   1260

aagctgaccg ttttaagaag tggcatgtgc cttgaaaggg ggcagaatgt tcagtcggtc   1320

gtgtttttaa cacagagtct ctagaagagg tgcagacatc ccgtctgact gtccctgtgg   1380

actctctcag ttgtatgttg ctataatcct ccaaatcaaa gctctttctg cttgtgcaag   1440

attgttccta ttaaacagtt ttaactaacc tttt                               1474


<210>  8964
<211>  210
<212>  PRT
<213>  Homo sapiens

<400>  8964

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Ser Pro Asn Gln Val Ala Glu Lys Val Ala 
            100                 105                 110


Ser Arg Ile Ala Glu Gly Phe Ser Asp Thr Ala Leu Ile Met Val Asp 
        115                 120                 125


Asn Thr Lys Phe Thr Met Asp Cys Val Ala Pro Thr Ile His Val Tyr 
    130                 135                 140


Glu His His Glu Asn Arg Trp Arg Cys Arg Asp Pro His His Asp Tyr 
145                 150                 155                 160


Cys Glu Asp Trp Pro Glu Ala Gln Arg Ile Ser Ala Ser Leu Leu Asp 
                165                 170                 175


Ser Arg Ser Tyr Glu Thr Leu Val Asp Phe Asp Asn His Leu Asp Asp 
            180                 185                 190


Ile Arg Asn Asp Trp Thr Asn Pro Glu Ile Asn Lys Ala Val Leu His 
        195                 200                 205


Leu Cys 
    210


<210>  8965
<211>  629
<212>  DNA
<213>  Homo sapiens

<400>  8965
ccggcggcgc cgggcgagaa gcgcgactgg agtctggggc tgcggcttcc cagaggcgcg     60

agtcgctttt ccaggagccg aggcccaaac ggggccgggc ctgaagggtc ccccgccagc    120

ccgcggccgc gccatcaatc gccgccgcct cgtcccgctt ctcggctgag gcgccgcgcg    180

gccaggcagc gggtccaggc ctcagccgcg cgcccagggg cctccggggc cctcccgggt    240

cagcatgccc ggggtgaaac tgaccaccca ggcctactgc aagatggtgc tgcacggcgc    300

caagtacccg cactgcgccg tcaacgggct cctggtggcc gagaagcaga agccgcgtaa    360

ggagcacctc cccctgggcg gccccggcgc ccaccacacc ctcttcgtgg actgcatccc    420

cctcttccac ggcaccctgg ccctcgcccc catgctggag gtggctctca ccctgattga    480

ttcatggtgc aaagatcata gctacgtgat tgctggttat tatcaagcta atgagcgagt    540

aaaggatgcc aggtacgtgg atgcagaacc ctctgtgggc gaggaagtga gcacgtgttg    600

ggcagacccc gtctctcgtg tgcttttcg                                      629


<210>  8966
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  8966

Met Pro Gly Val Lys Leu Thr Thr Gln Ala Tyr Cys Lys Met Val Leu 
1               5                   10                  15


His Gly Ala Lys Tyr Pro His Cys Ala Val Asn Gly Leu Leu Val Ala 
            20                  25                  30


Glu Lys Gln Lys Pro Arg Lys Glu His Leu Pro Leu Gly Gly Pro Gly 
        35                  40                  45


Ala His His Thr Leu Phe Val Asp Cys Ile Pro Leu Phe His Gly Thr 
    50                  55                  60


Leu Ala Leu Ala Pro Met Leu Glu Val Ala Leu Thr Leu Ile Asp Ser 
65                  70                  75                  80


Trp Cys Lys Asp His Ser Tyr Val Ile Ala Gly Tyr Tyr Gln Ala Asn 
                85                  90                  95


Glu Arg Val Lys Asp Ala Arg Tyr Val Asp Ala Glu Pro Ser Val Gly 
            100                 105                 110


Glu Glu Val Ser Thr Cys Trp Ala Asp Pro Val Ser Arg Val Leu 
        115                 120                 125


<210>  8967
<211>  408
<212>  DNA
<213>  Homo sapiens

<400>  8967
caagttagct gtatggatgg ctatgagggg tgcacacagc ccgttcacca actgaggaat     60

ggagaactcg aagggaggaa cggagactcg gccaagcctc agcactcaca gcggcagggt    120

ggatgagttc taataagggt agtttcctgt gacagtccgg aatctggaac taggcatcag    180

cccaaatggc tcctgcatga aaagctgcgg tggatctaag tggcagctag gagtcaaggc    240

aactagcttc ctccgaagcg aggcaagaca aggcacagcc gagaagccac tcaacctctg    300

ttcccaatga atccatttcc atgtccctgc ttcgctgtac gacaccccac accctgatgt    360

gcatcttgtg aaaaatcaag atgaaaataa aaggtcagga gaaaactc                 408


<210>  8968
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  8968

Met Asp Gly Tyr Glu Gly Cys Thr Gln Pro Val His Gln Leu Arg Asn 
1               5                   10                  15


Gly Glu Leu Glu Gly Arg Asn Gly Asp Ser Ala Lys Pro Gln His Ser 
            20                  25                  30


Gln Arg Gln Gly Gly 
        35


<210>  8969
<211>  1048
<212>  DNA
<213>  Homo sapiens

<400>  8969
cagggtgaga gccacctcca gcatgggggc gagggccagg gtgccgtgga agagggggat     60

gcagtccacg aagagggtgt ggtgggcgcc ggggccgccc agggggaggt gctccttacg    120

cggcttctgc ttctcggcca ccaggagccc gttgacggcg cagtgcgggt acttggcgcc    180

gtgcagcacc atcttgcagt aggcctgggt ggtcagtttc accccgggca tgctgacccg    240

ggagggcccc ggaggcccct gggcgcgcgg ctgaggcctg gacccgctgc ctggccgcgc    300

ggcgcctcag ccgagaagcg ggacgaggcg gcggcgattg atggcgcggc cgcgggctgg    360

cgggggaccc ttcaggcccg gccccgtttg ggcctcggct cctggaaaag cgactcgcgc    420

ctctgggaag ccgcagcccc agactccagt cgcgcttctc gcccggcgcc gccggaaagc    480

agcctctcca acgcctgccg gaaagcagcc cggcccggca ttttacgacg ttcgcagcgc    540

tacccttttc cgctccacgg tgacctccgt gcggccgggt gcgggcggag tcttcctcga    600

tcccgtggtg ctccgcggcg cggccttgct ctcttccggt cgcgggacac cgggtgtaga    660

gggcggtcgc ggcgggcagt ggcggcaggt gagacaggag gtggccggtg cggcgccgcc    720

aggccgggcc gggtcggggg gccgggagcc atcaagtctg cacgtccgca gcctggccgc    780

tcggcttcag caggaagcac cgaatgggcc tcggagccag gtgacattga ggccggcccg    840

tggggactcc gggctcggtg gctccaggct cggggggccg ccccgaagtg cccggtccat    900

cttacccggt ctcgcagcgg ctgcggaccg gcctcgggca ctgaccttgg agcgcccgct    960

ggccgagggc tcaggctgcg gggaggcggg cccgcgctct gtgcctgcag cctccgccct   1020

tgctccttca aaagggattg gaaattga                                      1048


<210>  8970
<211>  235
<212>  PRT
<213>  Homo sapiens

<400>  8970

Met Ala Arg Pro Arg Ala Gly Gly Gly Pro Phe Arg Pro Gly Pro Val 
1               5                   10                  15


Trp Ala Ser Ala Pro Gly Lys Ala Thr Arg Ala Ser Gly Lys Pro Gln 
            20                  25                  30


Pro Gln Thr Pro Val Ala Leu Leu Ala Arg Arg Arg Arg Lys Ala Ala 
        35                  40                  45


Ser Pro Thr Pro Ala Gly Lys Gln Pro Gly Pro Ala Phe Tyr Asp Val 
    50                  55                  60


Arg Ser Ala Thr Leu Phe Arg Ser Thr Val Thr Ser Val Arg Pro Gly 
65                  70                  75                  80


Ala Gly Gly Val Phe Leu Asp Pro Val Val Leu Arg Gly Ala Ala Leu 
                85                  90                  95


Leu Ser Ser Gly Arg Gly Thr Pro Gly Val Glu Gly Gly Arg Gly Gly 
            100                 105                 110


Gln Trp Arg Gln Val Arg Gln Glu Val Ala Gly Ala Ala Pro Pro Gly 
        115                 120                 125


Arg Ala Gly Ser Gly Gly Arg Glu Pro Ser Ser Leu His Val Arg Ser 
    130                 135                 140


Leu Ala Ala Arg Leu Gln Gln Glu Ala Pro Asn Gly Pro Arg Ser Gln 
145                 150                 155                 160


Val Thr Leu Arg Pro Ala Arg Gly Asp Ser Gly Leu Gly Gly Ser Arg 
                165                 170                 175


Leu Gly Gly Pro Pro Arg Ser Ala Arg Ser Ile Leu Pro Gly Leu Ala 
            180                 185                 190


Ala Ala Ala Asp Arg Pro Arg Ala Leu Thr Leu Glu Arg Pro Leu Ala 
        195                 200                 205


Glu Gly Ser Gly Cys Gly Glu Ala Gly Pro Arg Ser Val Pro Ala Ala 
    210                 215                 220


Ser Ala Leu Ala Pro Ser Lys Gly Ile Gly Asn 
225                 230                 235


<210>  8971
<211>  805
<212>  DNA
<213>  Homo sapiens

<400>  8971
acgacgttcg cagcgctacc cttttccgct ccacggtgac ctccgtgcgg ccgggtgcgg     60

gcggagtctt cctcgatccc gtggtgctcc gcggcgcggc cttgctctct tccggtcgcg    120

ggacaccggg tgtagagggc ggtcgcggcg ggcagtggcg gcagaatgtt ggctaccagg    180

gtatttagcc tagttggcaa gcgagcaatt tccacctctg tgtgtgtacg agctcatgaa    240

agtgttgtga agagcgaaga cttttcgctc ccagcttata tggatcggcg tgaccacccc    300

ttgccggagg tggcccatgt caagcacctg tctgccagcc agaaggcatt gaaggagaag    360

gagaaggcct cctggagcag cctctccatg gatgagaaag tcgagttgta tcgcattaag    420

ttcaaggaga gctttgctga gatgaacagg ggctcgaacg agtggaagac ggttgtgggc    480

ggtgccatgt tcttcatcgg tttcaccgcg ctcgttatca tgtggcagaa gcactatgtg    540

tacggccccc tcccgcaaag ctttgacaaa gagtgggtgg ccaagcagac caagaggatg    600

ctggacatga aggtgaaccc catccagggc ttagcctcca agtgggacta cgaaaagaac    660

gagtggaaga agtgagagat gctggcctgc gcctgcacct gcgcctggct ctgtcaccgc    720

catgcaactc catgcctatt tactggaaac ctgttatgcc aaacagttgt accactgcta    780

ataaatgacc agtttacctg aaacc                                          805


<210>  8972
<211>  169
<212>  PRT
<213>  Homo sapiens

<400>  8972

Met Leu Ala Thr Arg Val Phe Ser Leu Val Gly Lys Arg Ala Ile Ser 
1               5                   10                  15


Thr Ser Val Cys Val Arg Ala His Glu Ser Val Val Lys Ser Glu Asp 
            20                  25                  30


Phe Ser Leu Pro Ala Tyr Met Asp Arg Arg Asp His Pro Leu Pro Glu 
        35                  40                  45


Val Ala His Val Lys His Leu Ser Ala Ser Gln Lys Ala Leu Lys Glu 
    50                  55                  60


Lys Glu Lys Ala Ser Trp Ser Ser Leu Ser Met Asp Glu Lys Val Glu 
65                  70                  75                  80


Leu Tyr Arg Ile Lys Phe Lys Glu Ser Phe Ala Glu Met Asn Arg Gly 
                85                  90                  95


Ser Asn Glu Trp Lys Thr Val Val Gly Gly Ala Met Phe Phe Ile Gly 
            100                 105                 110


Phe Thr Ala Leu Val Ile Met Trp Gln Lys His Tyr Val Tyr Gly Pro 
        115                 120                 125


Leu Pro Gln Ser Phe Asp Lys Glu Trp Val Ala Lys Gln Thr Lys Arg 
    130                 135                 140


Met Leu Asp Met Lys Val Asn Pro Ile Gln Gly Leu Ala Ser Lys Trp 
145                 150                 155                 160


Asp Tyr Glu Lys Asn Glu Trp Lys Lys 
                165


<210>  8973
<211>  1083
<212>  DNA
<213>  Homo sapiens

<400>  8973
gacgttcgca gcgctaccct tttccgctcc acggtgacct ccgtgcggcc gggtgcgggc     60

ggagtcttcc tcgatcccgt ggtgctccgc ggcgcggcct tgctctcttc cggtcgcggg    120

acaccgggtg tagagggcgg tcgcggcggg cagtggcggc agaatgttgg ctaccagggt    180

atttagccta gttggcaagc gagcaatttc cacctctgtg tgtgtacgag ctcatgaaag    240

tgttgtgaag agcgaagact tttcgctccc agcttatatg gatcggcgtg accacccctt    300

gccggaggtg gcccatgtca agcacctgtc tgccagccag aaggcattga aggagaagga    360

gaaggcctcc tggagcagcc tctccatgga tgagaaagtc gagttgtatc gcattaagtt    420

caaggagagc tttgctgaga tgaacagggg ctcgaacgag tggaagacgg ttgtgggcgg    480

tgccatgttc ttcatcggtt tcaccgcgct cgttatcatg tggcagaagc actatggtca    540

ccttgggctc tgtttgtcag atcctgttat ccatagcctt tagagaggac cttctgcttt    600

tagcttattt tgttgctaac tttttacaaa caaagggcta attttaaaat gtcagtgttg    660

tcagtggtca gaaaccgtgt gtttgagcgg gtgttgagtg gcaggtggct ctgctgacct    720

ggtggctggt gtgtcgggag gatttaacct gtgtgaggga ttggcctaga aacaacctgt    780

tgagatagtc ttgccccata acctgtctca caccgtagtg tacggccccc tcccgcaaag    840

ctttgacaaa gagtgggtgg ccaagcagac caagaggatg ctggacatga aggtgaaccc    900

catccagggc ttagcctcca agtgggacta cgaaaagaac gagtggaaga agtgagagat    960

gctggcctgc gcctgcacct gcgcctggct ctgtcaccgc catgcaactc catgcctatt   1020

tactggaaac ctgttatgcc aaacagttgt accactgcta ataaatgacc agtttacctg   1080

aaa                                                                 1083


<210>  8974
<211>  139
<212>  PRT
<213>  Homo sapiens

<400>  8974

Met Leu Ala Thr Arg Val Phe Ser Leu Val Gly Lys Arg Ala Ile Ser 
1               5                   10                  15


Thr Ser Val Cys Val Arg Ala His Glu Ser Val Val Lys Ser Glu Asp 
            20                  25                  30


Phe Ser Leu Pro Ala Tyr Met Asp Arg Arg Asp His Pro Leu Pro Glu 
        35                  40                  45


Val Ala His Val Lys His Leu Ser Ala Ser Gln Lys Ala Leu Lys Glu 
    50                  55                  60


Lys Glu Lys Ala Ser Trp Ser Ser Leu Ser Met Asp Glu Lys Val Glu 
65                  70                  75                  80


Leu Tyr Arg Ile Lys Phe Lys Glu Ser Phe Ala Glu Met Asn Arg Gly 
                85                  90                  95


Ser Asn Glu Trp Lys Thr Val Val Gly Gly Ala Met Phe Phe Ile Gly 
            100                 105                 110


Phe Thr Ala Leu Val Ile Met Trp Gln Lys His Tyr Gly His Leu Gly 
        115                 120                 125


Leu Cys Leu Ser Asp Pro Val Ile His Ser Leu 
    130                 135


<210>  8975
<211>  1810
<212>  DNA
<213>  Homo sapiens

<400>  8975
tccgctccac ggtgacctcc gtgcggccgg gtgcgggcgg agtcttcctc gatcccgtgg     60

tgctccgcgg cgcggccttg ctctcttccg gtcgcgggac accgggtgta gagggcggtc    120

gcggcgggca gtggcggcag aatgttggct accagggtat ttagcctagt tggcaagcga    180

gcaatttcca cctctgtgtg tgtacgagct catgaaagtg ttgtgaagag cgaagacttt    240

tcgctcccag cttatatgga tcggcgtgac caccccttgc cggaggtggc ccatgtcaag    300

cacctgtctg ccagccagaa ggcattgaag gagaaggaga aggcctcctg gagcagcctc    360

tccatggatg agaaagtcga gtgtgggtat tgaagggacc cacaggcgcg cccagcagct    420

ctcggaagcc tctgtgtttc ctccttcaca agtgtggttt tggggagaag tggttgaatg    480

ttgcagagga gggagctgct gacctttgtg cctgtaaatg gctgtcctct ctgcccccag    540

tgtatcgcat taagttcaag gagagctttg ctgagatgaa caggggctcg aacgagtgga    600

agacggttgt gggcggtgcc atgttcttca tcggtttcac cgcgctcgtt atcatgtggc    660

agaagcacta tggtgagtag agagggagga aggcatgggc gcctggactg gggctccagc    720

ctgcagtgcc cattggtggg ctgtcgggga cctccatacc ttgaggctat gagataggga    780

ctgcattcca gagttcatct caggattgtt tccaggcctt ggtgacctgg agaactgaag    840

tcgtgggagg ttagtttata agccagcatc tgattattca tagccatgct tgttgggtgg    900

tgaaatacct taactacttt gtacagcaca ccacgttttc agtagcaatt tatgtgctca    960

ccagtcactt agcgaaagat gacttcgtga aggttcgagc aaggataagg ggactcattc   1020

attgaatgac tgtctggact gttgtgagga ctgcatctca acagccagca tctgggggtc   1080

ccgacctgat agtttgtgtg tgggcattgc cgggttgctc gctcgtggta atgactcttc   1140

cccgaggttc tttctgtcca ggcagaacag gcatttttgc attctgaata ggtatattct   1200

cgtacttttg gtttgaatgt ggatgtgggt taataacaga cccgaatcta tttgatcttc   1260

caggtcacct tgggctctgt ttgtcagatc ctgttatcca tagcctttag agaggacctt   1320

ctgcttttag cttattttgt tgctaacttt ttacaaacaa agggctaatt ttaaaatgtc   1380

agtgttgtca gtggtcagaa accgtgtgtt tgagcgggtg ttgagtggca ggtggctctg   1440

ctgacctggt ggctggtgtg tcgggaggat ttaacctgtg tgagggattg gcctagaaac   1500

aacctgttga gatagtcttg ccccataacc tgtctcacac cgtagtgtac ggccccctcc   1560

cgcaaagctt tgacaaagag tgggtggcca agcagaccaa gaggatgctg gacatgaagg   1620

tgaaccccat ccagggctta gcctccaagt gggactacga aaagaacgag tggaagaagt   1680

gagagatgct ggcctgcgcc tgcacctgcg cctggctctg tcaccgccat gcaactccat   1740

gcctatttac tggaaacctg ttatgccaaa cagttgtacc actgctaata aatgaccagt   1800

ttacctgaaa                                                          1810


<210>  8976
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  8976

Met Leu Ala Thr Arg Val Phe Ser Leu Val Gly Lys Arg Ala Ile Ser 
1               5                   10                  15


Thr Ser Val Cys Val Arg Ala His Glu Ser Val Val Lys Ser Glu Asp 
            20                  25                  30


Phe Ser Leu Pro Ala Tyr Met Asp Arg Arg Asp His Pro Leu Pro Glu 
        35                  40                  45


Val Ala His Val Lys His Leu Ser Ala Ser Gln Lys Ala Leu Lys Glu 
    50                  55                  60


Lys Glu Lys Ala Ser Trp Ser Ser Leu Ser Met Asp Glu Lys Val Glu 
65                  70                  75                  80


Cys Gly Tyr 



<210>  8977
<211>  2271
<212>  DNA
<213>  Homo sapiens

<400>  8977
cggtgacctc cgtgcggccg ggtgcgggcg gagtcttcct cgatcccgtg gtgctccgcg     60

gcgcggcctt gctctcttcc ggtcgcggga caccgggtgt agagggcggt cgcggcgggc    120

agtggcggca gaatgttggc taccagggta tttagcctag ttggcaagcg agcaatttcc    180

acctctgtgt gtgtacgagc tcatgaaagt gttgtgaaga gcgaagactt ttcgctccca    240

gcttatatgg atcggcgtga ccaccccttg ccggaggtgg cccatgtcaa gcacctgtct    300

gccagccaga aggcattgaa ggagaaggag aaggcctcct ggagcagcct ctccatggat    360

gagaaagtcg agtgtgggta ttgaagggac ccacaggcgc gcccagcagc tctcggaagc    420

gtgtgtgtga cagagcctct gctcacttct gggcctactg tctagaggca gtcttgcaca    480

ggagggttgc tctgctgggt ttcggggtca ctgtgccagg gccccagttt atgtgctcac    540

cagtcactta gctctgccag ctgacaggat cttttgctag gcccccttct ctgtgctgag    600

tggaggtagc ctctcagcat atctgctggg taagacatag ttaactgtaa attattgaaa    660

gaaactcagc aaaatgcata gtgtttggta tgaaaggggc agaaaaataa caagattaaa    720

tagaccctaa tactgtaatt caagtaagaa ataattttgc agttttaatt tgcacctgaa    780

gcgaactgta tgcattttct tctttccttg ccctgtcaca tgcctgcgtg ggcacgtgtg    840

tgcacgtacg tgcgtgaaca tgatgtggcc tgggttggtg tatccttcag ctctgtgttt    900

cctccttcac aagtgtggtt ttggggagaa gtggttgaat gttgcagagg agggagctgc    960

tgacctttgt gcctgtaaat ggctgtcctc tctgccccca gtgtatcgca ttaagttcaa   1020

ggagagcttt gctgagatga acaggggctc gaacgagtgg aagacggttg tgggcggtgc   1080

catgttcttc atcggtttca ccgcgctcgt tatcatgtgg cagaagcact atggtgagta   1140

gagagggagg aaggcatggg cgcctggact ggggctccag cctgcagtgc ccattggtgg   1200

gctgtcgggg acctccatac cttgaggcta tgagataggg actgcattcc agagttcatc   1260

tcaggattgt ttccaggcct tggtgacctg gagaactgaa gtcgtgggag gttagtttat   1320

aagccagcat ctgattattc atagccatgc ttgttgggtg gtgaaatacc ttaactactt   1380

tgtacagcac accacgtttt cagtagcaat ttatgtgctc accagtcact tagcgaaaga   1440

tgacttcgtg aaggttcgag caaggataag gggactcatt cattgaatga ctgtctggac   1500

tgttgtgagg actgcatctc aacagccagc atctgggggt cccgacctga tagtttgtgt   1560

gtgggcattg ccgggttgct cgctcgtggt aatgactctt ccccgaggtt ctttctgtcc   1620

aggcagaaca ggcatttttg cattctgaat aggtatattc tcgtactttt ggtttgaatg   1680

tggatgtggg ttaataacag acccgaatct atttgatctt ccaggtcacc ttgggctctg   1740

tttgtcagat cctgttatcc atagccttta gagaggacct tctgctttta gcttattttg   1800

ttgctaactt tttacaaaca aagggctaat tttaaaatgt cagtgttgtc agtggtcaga   1860

aaccgtgtgt ttgagcgggt gttgagtggc aggtggctct gctgacctgg tggctggtgt   1920

gtcgggagga tttaacctgt gtgagggatt ggcctagaaa caacctgttg agatagtctt   1980

gccccataac ctgtctcaca ccgtagtgta cggccccctc ccgcaaagct ttgacaaaga   2040

gtgggtggcc aagcagacca agaggatgct ggacatgaag gtgaacccca tccagggctt   2100

agcctccaag tgggactacg aaaagaacga gtggaagaag tgagagatgc tggcctgcgc   2160

ctgcacctgc gcctggctct gtcaccgcca tgcaactcca tgcctattta ctggaaacct   2220

gttatgccaa acagttgtac cactgctaat aaatgaccag tttacctgaa a            2271


<210>  8978
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  8978

Met Leu Ala Thr Arg Val Phe Ser Leu Val Gly Lys Arg Ala Ile Ser 
1               5                   10                  15


Thr Ser Val Cys Val Arg Ala His Glu Ser Val Val Lys Ser Glu Asp 
            20                  25                  30


Phe Ser Leu Pro Ala Tyr Met Asp Arg Arg Asp His Pro Leu Pro Glu 
        35                  40                  45


Val Ala His Val Lys His Leu Ser Ala Ser Gln Lys Ala Leu Lys Glu 
    50                  55                  60


Lys Glu Lys Ala Ser Trp Ser Ser Leu Ser Met Asp Glu Lys Val Glu 
65                  70                  75                  80


Cys Gly Tyr 



<210>  8979
<211>  347
<212>  DNA
<213>  Homo sapiens

<400>  8979
ctcgatcccg tggtgctccg cggcgcggcc ttgctctctt ccggtcgcgg gacaccgggt     60

gtagagggcg gtcgcggcgg gcagtggcgg cagaatgttg gctaccaggg tatttagcct    120

agttggcaac agaccaagag gatgctggac atgaaggtga accccatcca gggcttagcc    180

tccaagtggg actacgaaaa gaacgagtgg aagaagtgag agatgctggc ctgcgcctgc    240

acctgcgcct ggctctgtca ccgccatgca actccatgcc tatttactgg aaacctgtta    300

tgccaaacag ttgtaccact gctaataaat gaccagttta cctgaaa                  347


<210>  8980
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  8980

Met Leu Ala Cys Ala Cys Thr Cys Ala Trp Leu Cys His Arg His Ala 
1               5                   10                  15


Thr Pro Cys Leu Phe Thr Gly Asn Leu Leu Cys Gln Thr Val Val Pro 
            20                  25                  30


Leu Leu Ile Asn Asp Gln Phe Thr 
        35                  40


<210>  8981
<211>  2087
<212>  DNA
<213>  Homo sapiens

<400>  8981
ggtcgcggga caccgggtgt agagggcggt cgcggcgggc agtggcggca gaatgttggc     60

taccagggta tttagcctag ttggcaagcg agcaatttcc acctctgtgt gtgtacgagc    120

tcatgaaagt gttgtgaaga gcgaagactt ttcgctccca cagcctctcc atggatgaga    180

aagtcgagtg tgggtattga agggacccac aggcgcgccc agcagctctc ggaagcgtgt    240

gtgtgacaga gcctctgctc acttctgggc ctactgtcta gaggcagtct tgcacaggag    300

ggttgctctg ctgggtttcg gggtcactgt gccagggccc cagtttatgt gctcaccagt    360

cacttagctc tgccagctga caggatcttt tgctaggccc ccttctctgt gctgagtgga    420

ggtagcctct cagcatatct gctgggtaag acatagttaa ctgtaaatta ttgaaagaaa    480

ctcagcaaaa tgcatagtgt ttggtatgaa aggggcagaa aaataacaag attaaataga    540

ccctaatact gtaattcaag taagaaataa ttttgcagtt ttaatttgca cctgaagcga    600

actgtatgca ttttcttctt tccttgccct gtcacatgcc tgcgtgggca cgtgtgtgca    660

cgtacgtgcg tgaacatgat gtggcctggg ttggtgtatc cttcagctct gtgtttcctc    720

cttcacaagt gtggttttgg ggagaagtgg ttgaatgttg cagaggaggg agctgctgac    780

ctttgtgcct gtaaatggct gtcctctctg cccccagtgt atcgcattaa gttcaaggag    840

agctttgctg agatgaacag gggctcgaac gagtggaaga cggttgtggg cggtgccatg    900

ttcttcatcg gtttcaccgc gctcgttatc atgtggcaga agcactatgg tgagtagaga    960

gggaggaagg catgggcgcc tggactgggg ctccagcctg cagtgcccat tggtgggctg   1020

tcggggacct ccataccttg aggctatgag atagggactg cattccagag ttcatctcag   1080

gattgtttcc aggccttggt gacctggaga actgaagtcg tgggaggtta gtttataagc   1140

cagcatctga ttattcatag ccatgcttgt tgggtggtga aataccttaa ctactttgta   1200

cagcacacca cgttttcagt agcaatttat gtgctcacca gtcacttagc gaaagatgac   1260

ttcgtgaagg ttcgagcaag gataagggga ctcattcatt gaatgactgt ctggactgtt   1320

gtgaggactg catctcaaca gccagcatct gggggtcccg acctgatagt ttgtgtgtgg   1380

gcattgccgg gttgctcgct cgtggtaatg actcttcccc gaggttcttt ctgtccaggc   1440

agaacaggca tttttgcatt ctgaataggt atattctcgt acttttggtt tgaatgtgga   1500

tgtgggttaa taacagaccc gaatctattt gatcttccag gtcaccttgg gctctgtttg   1560

tcagatcctg ttatccatag cctttagaga ggaccttctg cttttagctt attttgttgc   1620

taacttttta caaacaaagg gctaatttta aaatgtcagt gttgtcagtg gtcagaaacc   1680

gtgtgtttga gcgggtgttg agtggcaggt ggctctgctg acctggtggc tggtgtgtcg   1740

ggaggattta acctgtgtga gggattggcc tagaaacaac ctgttgagat agtcttgccc   1800

cataacctgt ctcacaccgt agtgtacggc cccctcccgc aaagctttga caaagagtgg   1860

gtggccaagc agaccaagag gatgctggac atgaaggtga accccatcca gggcttagcc   1920

tccaagtggg actacgaaaa gaacgagtgg aagaagtgag agatgctggc ctgcgcctgc   1980

acctgcgcct ggctctgtca ccgccatgca actccatgcc tatttactgg aaacctgtta   2040

tgccaaacag ttgtaccact gctaataaat gaccagttta cctgaaa                 2087


<210>  8982
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  8982

Met Leu Ala Thr Arg Val Phe Ser Leu Val Gly Lys Arg Ala Ile Ser 
1               5                   10                  15


Thr Ser Val Cys Val Arg Ala His Glu Ser Val Val Lys Ser Glu Asp 
            20                  25                  30


Phe Ser Leu Pro Gln Pro Leu His Gly 
        35                  40


<210>  8983
<211>  644
<212>  DNA
<213>  Homo sapiens

<400>  8983
gggacaccgg gtgtagaggg cggtcgcggc gggcagtggc ggcagaatgt tggctaccag     60

ggtatttagc ctagttggca agcgagcaat ttccacctct gtgtgtgtac gagctcatga    120

aagtgttgtg aagagcgaag acttttcgct cccagcttat atggatcggc gtgaccaccc    180

cttgccggag gtggcccatg tcaagcacct gtctgccagc cagaaggcat tgaaggagaa    240

ggagaaggcc tcctggagca gcctctccat ggatgagaaa gtcgagtgtg ggtattgaag    300

ggacccacag gcgcgcccag cagctctcgg aagcgttgta tcgcattaag ttcaaggaga    360

gctttgctga gatgaacagg ggctcgaacg agtggaagac ggttgtgggc ggtgccatgt    420

tcttcatcgg tttcaccgcg ctcgttatca tgtggcagaa gcactatggg cttagcctcc    480

aagtgggact acgaaaagaa cgagtggaag aagtgagaga tgctggcctg cgcctgcacc    540

tgcgcctggc tctgtcaccg ccatgcaact ccatgcctat ttactggaaa cctgttatgc    600

caaacagttg taccactgct aataaatgac cagtttacct gaaa                     644


<210>  8984
<211>  118
<212>  PRT
<213>  Homo sapiens

<400>  8984

Met Arg Lys Ser Ser Val Gly Ile Glu Gly Thr His Arg Arg Ala Gln 
1               5                   10                  15


Gln Leu Ser Glu Ala Leu Tyr Arg Ile Lys Phe Lys Glu Ser Phe Ala 
            20                  25                  30


Glu Met Asn Arg Gly Ser Asn Glu Trp Lys Thr Val Val Gly Gly Ala 
        35                  40                  45


Met Phe Phe Ile Gly Phe Thr Ala Leu Val Ile Met Trp Gln Lys His 
    50                  55                  60


Tyr Gly Leu Ser Leu Gln Val Gly Leu Arg Lys Glu Arg Val Glu Glu 
65                  70                  75                  80


Val Arg Asp Ala Gly Leu Arg Leu His Leu Arg Leu Ala Leu Ser Pro 
                85                  90                  95


Pro Cys Asn Ser Met Pro Ile Tyr Trp Lys Pro Val Met Pro Asn Ser 
            100                 105                 110


Cys Thr Thr Ala Asn Lys 
        115


<210>  8985
<211>  773
<212>  DNA
<213>  Homo sapiens

<400>  8985
ggtgagacag gaggtggccg gtgcggcgcc gccaggccgg gccgggtcgg ggggccggga     60

gccatcaagt ctgcacgtcc gcagcctggc cgctcggctt cagcaggaag caccgaatgg    120

gcctcggagc cagaatgttg gctaccaggg tatttagcct agttggcaag cgagcaattt    180

ccacctctgt gtgtgtacga gctcatgaaa gtgttgtgaa gagcgaagac ttttcgctcc    240

cagcttatat ggatcggcgt gaccacccct tgccggaggt ggcccatgtc aagcacctgt    300

ctgccagcca gaaggcattg aaggagaagg agaaggcctc ctggagcagc ctctccatgg    360

atgagaaagt cgagttgtat cgcattaagt tcaaggagag ctttgctgag atgaacaggg    420

gctcgaacga gtggaagacg gttgtgggcg gtgccatgtt cttcatcggt ttcaccgcgc    480

tcgttatcat gtggcagaag cactatgtgt acggccccct cccgcaaagc tttgacaaag    540

agtgggtggc caagcagacc aagaggatgc tggacatgaa ggtgaacccc atccagggct    600

tagcctccaa gtgggactac gaaaagaacg agtggaagaa gtgagagatg ctggcctgcg    660

cctgcacctg cgcctggctc tgtcaccgcc atgcaactcc atgcctattt actggaaacc    720

tgttatgcca aacagttgta ccactgctaa taaatgacca gtttacctga aac           773


<210>  8986
<211>  175
<212>  PRT
<213>  Homo sapiens

<400>  8986

Met Gly Leu Gly Ala Arg Met Leu Ala Thr Arg Val Phe Ser Leu Val 
1               5                   10                  15


Gly Lys Arg Ala Ile Ser Thr Ser Val Cys Val Arg Ala His Glu Ser 
            20                  25                  30


Val Val Lys Ser Glu Asp Phe Ser Leu Pro Ala Tyr Met Asp Arg Arg 
        35                  40                  45


Asp His Pro Leu Pro Glu Val Ala His Val Lys His Leu Ser Ala Ser 
    50                  55                  60


Gln Lys Ala Leu Lys Glu Lys Glu Lys Ala Ser Trp Ser Ser Leu Ser 
65                  70                  75                  80


Met Asp Glu Lys Val Glu Leu Tyr Arg Ile Lys Phe Lys Glu Ser Phe 
                85                  90                  95


Ala Glu Met Asn Arg Gly Ser Asn Glu Trp Lys Thr Val Val Gly Gly 
            100                 105                 110


Ala Met Phe Phe Ile Gly Phe Thr Ala Leu Val Ile Met Trp Gln Lys 
        115                 120                 125


His Tyr Val Tyr Gly Pro Leu Pro Gln Ser Phe Asp Lys Glu Trp Val 
    130                 135                 140


Ala Lys Gln Thr Lys Arg Met Leu Asp Met Lys Val Asn Pro Ile Gln 
145                 150                 155                 160


Gly Leu Ala Ser Lys Trp Asp Tyr Glu Lys Asn Glu Trp Lys Lys 
                165                 170                 175


<210>  8987
<211>  594
<212>  DNA
<213>  Homo sapiens

<400>  8987
caccacgttt tcagtagcaa tttatgtgct caccagtcac ttagcgaaag atgacttcgt     60

gaaggttcga gcaaggataa ggggactcat tcattgaatg actgtctgga ctgttgtgag    120

gactgcatct caacagccag catctggggg tcccgacctg atagtttgtg tgtgggcatt    180

gccgggttgc tcgctcgtgg taatgactct tccccgaggt tctttctgtc caggcagaac    240

aggcattttt gcattctgaa taggtatatt ctcgtacttt tggtttgaat gtggatgtgg    300

gttaataaca gacccgaatc tatttgatct tccaggtcac cttgggctct gtttgtcaga    360

tcctgttatc catagccttt agagaaggat gctggacatg aaggtgaacc ccatccaggg    420

cttagcctcc aagtgggact acgaaaagaa cgagtggaag aagtgagaga tgctggcctg    480

cgcctgcacc tgcgcctggc tctgtcaccg ccatgcaact ccatgcctat ttactggaaa    540

cctgttatgc caaacagttg taccactgct aataaatgac cagtttacct gaaa          594


<210>  8988
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  8988

Met Thr Val Trp Thr Val Val Arg Thr Ala Ser Gln Gln Pro Ala Ser 
1               5                   10                  15


Gly Gly Pro Asp Leu Ile Val Cys Val Trp Ala Leu Pro Gly Cys Ser 
            20                  25                  30


Leu Val Val Met Thr Leu Pro Arg Gly Ser Phe Cys Pro Gly Arg Thr 
        35                  40                  45


Gly Ile Phe Ala Phe 
    50


<210>  8989
<211>  895
<212>  DNA
<213>  Homo sapiens

<400>  8989
ctaccgcctc tgtgactacc gcctctatga ccgacgctgt tactacgact gtagccattg     60

ttcctaccgc ctctgtgact accgcctcta tgaccgacgc tggtactacg actgtagcca    120

ttgttcctac cgcctctgtg actaccgcct ctatgaccga cgctggtact acgactgtag    180

ccattgttcc taccgcctct gtgactaccg cctctatgac cgacgctggt actacgactg    240

tagccattgt tcctaccgcc tctgtgacta ccgcctctat gaccgacgct ggtactacga    300

ctgtagccat tgttcctacc gcctctgtga ctaccgcctc tgtgaccgac gctggtacta    360

cgactgtagc cattgttcct accgcctctg tgactaccgc ctctgtgacc gacgctggta    420

ctacgactgt agccattgtt cctaccgcct ctgtgactac cgcctctgtg accgacgctg    480

gtactacgac tgtagccatt gttcctaccg cctctgtgac taccgcctct gtgaccgacg    540

ctggtactac gactgtagcc attgttcctg ccgcctctgt gactaccgcc tctgtgaccg    600

acgctggtac tacgactgta gccattgttc ctaccgcctc tgtgactacc gcctctgtga    660

ccgacgctgg tactacgact gtagccattg ttcctaccgc ctctgtgact accgcctctg    720

tgaccgacgc tggtactacg actgtagcca ttgttcctgc cgcctctgtg actaccgcct    780

ctgtgaccga cgctggtact acgactgtag ccattgttcc tgccgcctct gtgactaccg    840

cctctgtgac cgacgctggt actacgactg tagccattgt tcctgccgcc tctgt         895


<210>  8990
<211>  288
<212>  PRT
<213>  Homo sapiens

<400>  8990

Met Thr Asp Ala Val Thr Thr Thr Val Ala Ile Val Pro Thr Ala Ser 
1               5                   10                  15


Val Thr Thr Ala Ser Met Thr Asp Ala Gly Thr Thr Thr Val Ala Ile 
            20                  25                  30


Val Pro Thr Ala Ser Val Thr Thr Ala Ser Met Thr Asp Ala Gly Thr 
        35                  40                  45


Thr Thr Val Ala Ile Val Pro Thr Ala Ser Val Thr Thr Ala Ser Met 
    50                  55                  60


Thr Asp Ala Gly Thr Thr Thr Val Ala Ile Val Pro Thr Ala Ser Val 
65                  70                  75                  80


Thr Thr Ala Ser Met Thr Asp Ala Gly Thr Thr Thr Val Ala Ile Val 
                85                  90                  95


Pro Thr Ala Ser Val Thr Thr Ala Ser Val Thr Asp Ala Gly Thr Thr 
            100                 105                 110


Thr Val Ala Ile Val Pro Thr Ala Ser Val Thr Thr Ala Ser Val Thr 
        115                 120                 125


Asp Ala Gly Thr Thr Thr Val Ala Ile Val Pro Thr Ala Ser Val Thr 
    130                 135                 140


Thr Ala Ser Val Thr Asp Ala Gly Thr Thr Thr Val Ala Ile Val Pro 
145                 150                 155                 160


Thr Ala Ser Val Thr Thr Ala Ser Val Thr Asp Ala Gly Thr Thr Thr 
                165                 170                 175


Val Ala Ile Val Pro Ala Ala Ser Val Thr Thr Ala Ser Val Thr Asp 
            180                 185                 190


Ala Gly Thr Thr Thr Val Ala Ile Val Pro Thr Ala Ser Val Thr Thr 
        195                 200                 205


Ala Ser Val Thr Asp Ala Gly Thr Thr Thr Val Ala Ile Val Pro Thr 
    210                 215                 220


Ala Ser Val Thr Thr Ala Ser Val Thr Asp Ala Gly Thr Thr Thr Val 
225                 230                 235                 240


Ala Ile Val Pro Ala Ala Ser Val Thr Thr Ala Ser Val Thr Asp Ala 
                245                 250                 255


Gly Thr Thr Thr Val Ala Ile Val Pro Ala Ala Ser Val Thr Thr Ala 
            260                 265                 270


Ser Val Thr Asp Ala Gly Thr Thr Thr Val Ala Ile Val Pro Ala Ala 
        275                 280                 285


<210>  8991
<211>  631
<212>  DNA
<213>  Homo sapiens

<400>  8991
tatggaagaa tcccttgagc ccaggagttg gaggctgcgg tgagctacga ttgcaccagt     60

gcactccagc ttgggtgaca gagcgagacc ctgtctccaa aaaaaaaaaa aaaaaaaaaa    120

agatgaggaa atcgcccgag gatggatccg acttgtggtt tcaatggagc cctcattctt    180

ctcttcactt accctctccg tgaggaggaa gccagtgcac atcaagcgtt tcctgtgtag    240

cacagactct tctcccaaac atctttgcat tctgcactgg tgagggccag tggtgccaca    300

ccaatgtccc aattcacctt gggaacgtcc ttgagcgcat ttctttttgt ctgtagaagt    360

aaaagagtag aactgaatgc cgaagccagc aagctgttgg aaccttggaa acgcagaggg    420

catgaaggct gagtccgggg tcctacagtc agaggctcgc attcaaatct tgcctctgcc    480

tgtaattgcc gtgggaccct agcaggtgac ttagccatgc cctgcctggg tttacctacc    540

tgtaaagagc ccttgtaagg atgaaagtag gtggcacaga ccaagcatct gtacctggca    600

gaccagtcct taataaacag gaattattgt t                                   631


<210>  8992
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  8992

Met Ser Gln Phe Thr Leu Gly Thr Ser Leu Ser Ala Phe Leu Phe Val 
1               5                   10                  15


Cys Arg Ser Lys Arg Val Glu Leu Asn Ala Glu Ala Ser Lys Leu Leu 
            20                  25                  30


Glu Pro Trp Lys Arg Arg Gly His Glu Gly 
        35                  40


<210>  8993
<211>  715
<212>  DNA
<213>  Homo sapiens

<400>  8993
tgaaaaagtt gagaagccag atactaaaga gaaaaaaaga aggagaaggt tcttgcagct     60

gttacaaaac cagttggtgg tgacaagaac ggcggtaccc gggtggttaa acttcgcaaa    120

atgcctagat agtatcctac tgaagatgtg cctcgaaagc tgttgagcca cggcaaaaaa    180

cccttcagtc agcacgtgag aaaactgcga gccagcatta cccccgggac cattctgatc    240

atcctcactg gacgccacag gggcaagagg gtggttttcc tgaagcagct ggctagtggc    300

ttattacttg tgactggacc tctggtcctc aatcgagttc ctctacgaag aacacaccag    360

aaatttgtca ttgccacctc aaccaaaatc gatatcagca atgtaaaaat cccaaaacat    420

cttactgatg cttacttcaa gaagaagaag ctgcggaagc ccagacacca ggaaggtgag    480

atcttcgaca cagaaaaaga gaaatatgag attacggagc agcgcaagat tgatcagaaa    540

gctgtggact cacaaatttt accaaaaatc aaagctattc ctcagctcca gggctacctg    600

cgatctgtgt ttgctctgac gaatggaatt tatcctcaca aattggtgtt ctaaatgtct    660

taagaaccta attaaatagc tgactacaaa aaaaaaaaaa aaaaaaaaaa gacac         715


<210>  8994
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  8994

Met Leu Thr Ser Arg Arg Arg Ser Cys Gly Ser Pro Asp Thr Arg Lys 
1               5                   10                  15


Val Arg Ser Ser Thr Gln Lys Lys Arg Asn Met Arg Leu Arg Ser Ser 
            20                  25                  30


Ala Arg Leu Ile Arg Lys Leu Trp Thr His Lys Phe Tyr Gln Lys Ser 
        35                  40                  45


Lys Leu Phe Leu Ser Ser Arg Ala Thr Cys Asp Leu Cys Leu Leu 
    50                  55                  60


<210>  8995
<211>  831
<212>  DNA
<213>  Homo sapiens

<400>  8995
ctctttccca tcttgcaaga tggcaggtga aaaagttgag aagccagata ctaaagagaa     60

gaaacccgaa gccaagaagg ttgatgctgg tggcaagaaa ggccatgtag aagaggaagt    120

actcagccgc taaatccaag gttgaaaaga aaaagaagga gaaggttctt gcagctgtta    180

caaaaccagt tggtggtgac aagaacggcg gtacccgggt ggttaaactt cgcaaaatgc    240

ctagatagta tcctactgaa gatgtgcctc gaaagctgtt gagccacggc aaaaaaccct    300

tcagtcagca cgtgagaaaa ctgcgagcca gcattacccc cgggaccatt ctgatcatcc    360

tcactggacg ccacaggggc aagagggtgg ttttcctgaa gcagctggct agtggcttat    420

tacttgtgac tggacctctg gtcctcaatc gagttcctct acgaagaaca caccagaaat    480

ttgtcattgc cacctcaacc aaaatcgata tcagcaatgt aaaaatccca aaacatctta    540

ctgatgctta cttcaagaag aagaagctgc ggaagcccag acaccaggaa ggtgagatct    600

tcgacacaga aaaagagaaa tatgagatta cggagcagcg caagattgat cagaaagctg    660

tggactcaca aattttacca aaaatcaaag ctattcctca gctccagggc tacctgcgat    720

ctgtgtttgc tctgacgaat ggaatttatc ctcacaaatt ggtgttctaa atgtcttaag    780

aacctaatta aatagctgac tacaaaaaaa aaaaaaaaaa aaaaaagaca c             831


<210>  8996
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  8996

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Lys Gly His Val Glu Glu 
            20                  25                  30


Glu Val Leu Ser Arg 
        35


<210>  8997
<211>  802
<212>  DNA
<213>  Homo sapiens

<400>  8997
tgctctttcc catcttgcaa gatggcaggt gaaaaagttg agaagccaga tactaaagag     60

aagaaacccg aagccaagaa ggttgatgct ggtggcaagg tgaaaaaggg taacctcaaa    120

gctaaaaagc ccaagaaggg gaagccccat tgcagccgca accctgtcct tgtcagagga    180

attggcaggt attcccgatc tgccatgtat tccagaaagg ccatgtagaa gaggaagtac    240

tcagccgcta aatccaaggt tgaaaagaaa aagaaggaga aggttcttgc agctgttaca    300

aaaccagttg gtggtgacat tctgatcatc ctcactggac gccacagggg caagagggtg    360

gttttcctga agcagctggc tagtggctta ttacttgtga ctggacctct ggtcctcaat    420

cgagttcctc tacgaagaac acaccagaaa tttgtcattg ccacctcaac caaaatcgat    480

atcagcaatg taaaaatccc aaaacatctt actgatgctt acttcaagaa gaagaagctg    540

cggaagccca gacaccagga aggtgagatc ttcgacacag aaaaagagaa atatgagatt    600

acggagcagc gcaagattga tcagaaagct gtggactcac aaattttacc aaaaatcaaa    660

gctattcctc agctccaggg ctacctgcga tctgtgtttg ctctgacgaa tggaatttat    720

cctcacaaat tggtgttcta aatgtcttaa gaacctaatt aaatagctga ctacaaaaaa    780

aaaaaaaaaa aaaaaaagac ac                                             802


<210>  8998
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  8998

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60


Arg Lys Ala Met 
65


<210>  8999
<211>  528
<212>  DNA
<213>  Homo sapiens

<400>  8999
ctctttccca tcttgcaaga tggcaggtga aaaagttgag aagccagata ctaaagagaa     60

gaaacccgaa gccaagaagg ttgatggtgg ttttcctgaa gcagctggct agtggcttat    120

tacttgtgac tggacctctg gtcctcaatc gagttcctct acgaagaaca caccagaaat    180

ttgtcattgc cacctcaacc aaaatcgata tcagcaatgt aaaaatccca aaacatctta    240

ctgatgctta cttcaagaag aagaagctgc ggaagcccag acaccaggaa ggtgagatct    300

tcgacacaga aaaagagaaa tatgagatta cggagcagcg caagattgat cagaaagctg    360

tggactcaca aattttacca aaaatcaaag ctattcctca gctccagggc tacctgcgat    420

ctgtgtttgc tctgacgaat ggaatttatc ctcacaaatt ggtgttctaa atgtcttaag    480

aacctaatta aatagctgac tacaaaaaaa aaaaaaaaaa aaaaaaga                 528


<210>  9000
<211>  128
<212>  PRT
<213>  Homo sapiens

<400>  9000

Met Val Val Phe Leu Lys Gln Leu Ala Ser Gly Leu Leu Leu Val Thr 
1               5                   10                  15


Gly Pro Leu Val Leu Asn Arg Val Pro Leu Arg Arg Thr His Gln Lys 
            20                  25                  30


Phe Val Ile Ala Thr Ser Thr Lys Ile Asp Ile Ser Asn Val Lys Ile 
        35                  40                  45


Pro Lys His Leu Thr Asp Ala Tyr Phe Lys Lys Lys Lys Leu Arg Lys 
    50                  55                  60


Pro Arg His Gln Glu Gly Glu Ile Phe Asp Thr Glu Lys Glu Lys Tyr 
65                  70                  75                  80


Glu Ile Thr Glu Gln Arg Lys Ile Asp Gln Lys Ala Val Asp Ser Gln 
                85                  90                  95


Ile Leu Pro Lys Ile Lys Ala Ile Pro Gln Leu Gln Gly Tyr Leu Arg 
            100                 105                 110


Ser Val Phe Ala Leu Thr Asn Gly Ile Tyr Pro His Lys Leu Val Phe 
        115                 120                 125


<210>  9001
<211>  696
<212>  DNA
<213>  Homo sapiens

<400>  9001
gctctttccc atcttgcaag atggcaggtg aaaaagttga gaagccagat actaaagaga     60

agaaacccga agccaagaag gttgatgctg gtggcaaggt gaaaaagggt aacctcaaag    120

ctaaaaagcc caagaagggg aagccccatt gcagccgcaa ccctgtcctt gtcagaggaa    180

ttggcaggta ttcccgatct gccatgtatt ccagaaaggc catgtagaag aggaagtact    240

cagccgctaa atccaaggtt ttcctgaagc agctggctag tggcttatta cttgtgactg    300

gacctctggt cctcaatcga gttcctctac gaagaacaca ccagaaattt gtcattgcca    360

cctcaaccaa aatcgatatc agcaatgtaa aaatcccaaa acatcttact gatgcttact    420

tcaagaagaa gaagctgcgg aagcccagac accaggaagg tgagatcttc gacacagaaa    480

aagagaaata tgagattacg gagcagcgca agattgatca gaaagctgtg gactcacaaa    540

ttttaccaaa aatcaaagct attcctcagc tccagggcta cctgcgatct gtgtttgctc    600

tgacgaatgg aatttatcct cacaaattgg tgttctaaat gtcttaagaa cctaattaaa    660

tagctgacta caaaaaaaaa aaaaaaaaaa aaaaga                              696


<210>  9002
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  9002

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60


Arg Lys Ala Met 
65


<210>  9003
<211>  872
<212>  DNA
<213>  Homo sapiens

<400>  9003
tctttttttt tttttttttt tttttgtagt cagctattta attaggttct taagacattt     60

agaacaccaa tttgtgagga taaattccat tcgtcagagc aaacacagat cgcaggtagc    120

cctggagctg aggaatagct ttgatttttg gtaaaatttg tgagtccaca gctttctgat    180

caatcttgcg ctgctccgta atctcatatt tctctttttc tgtgtcgaag atctcacctt    240

cctggtgtct gggcttccgc agcttcttct tcttgaagta agcatcagta agatgttttg    300

ggatttttac attgctgata tcgattttgg ttgaggtggc aatgacaaat ttctggtgtg    360

ttcttcgtag aggaactcga ttgaggacca gaggtccagt cacaagtaat aagccactag    420

ccagctgctt caggaaaacc accctcttgc ccctgtggcg tccagtgagg atgatcagaa    480

tggtcccggg ggtaatgctg gctcgcagtt ttctcacgtg ctgagaagtt taaccacccg    540

ggtaccgccg ttcttgtcac caccaactgg ttttgtaaca gctgcaagaa ccttctcctt    600

ctttttcttt tcaaccttgg atttagcggc tgagtacttc ctcttctaca tggcctttct    660

ggaatacatg gcagatcggg aatacctgcc aattcctctg acaaggacag ggttgcggct    720

gcaatggggc ttccccttct tgggcttttt agctttgagg ttaccctttt tcaccttgcc    780

accagcatca accttcttgg cttcgggttt cttctcttta gtatctggct tctcaacttt    840

ttcacctgcc atcttgcaag atgggaaaga gc                                  872


<210>  9004
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  9004

Met Ala Phe Leu Glu Tyr Met Ala Asp Arg Glu Tyr Leu Pro Ile Pro 
1               5                   10                  15


Leu Thr Arg Thr Gly Leu Arg Leu Gln Trp Gly Phe Pro Phe Leu Gly 
            20                  25                  30


Phe Leu Ala Leu Arg Leu Pro Phe Phe Thr Leu Pro Pro Ala Ser Thr 
        35                  40                  45


Phe Leu Ala Ser Gly Phe Phe Ser Leu Val Ser Gly Phe Ser Thr Phe 
    50                  55                  60


Ser Pro Ala Ile Leu Gln Asp Gly Lys 
65                  70


<210>  9005
<211>  956
<212>  DNA
<213>  Homo sapiens

<400>  9005
aaaaaagaca ctgctctttc ccatcttgca agatggcagg tgaaaaagtt gagaagccag     60

atactaaaga gaagaaaccc gaagccaaga aggttgatgc tggtggcaag gtgaaaaagg    120

gtaacctcaa agctaaaaag cccaagaagg ggaagcccca ttgcagccgc aaccctgtcc    180

ttgtcagagg aattggcagg tattcccgat ctgccatgta ttccagaaag gccatgtaga    240

agaggaagta ctcagccgct aaatccaagg ttgaaaagaa aaagaaggag aaggttcttg    300

cagctgttac aaaaccagtt ggtggtgaca agaacggcgg tacccgggtg gttaaacttc    360

gcaaaatgcc tagatagtat cctactgaag atgtgcctcg aaagctgttg agccacggca    420

aaaaaccctt cagtcagcac gtgagaaaac tgcgagccag cattaccccc gggaccattc    480

tgatcatcct cactggacgc cacaggggca agagggtggt tttcctgaag cagctggcta    540

gtggcttatt acttgtgact ggacctctgg tcctcaatcg agttcctcta cgaagaacac    600

accagaaatt tgtcattgcc acctcaacca aaatcgatat cagcaatgta aaaatcccaa    660

aacatcttac tgatgcttac ttcaagaaga agaagctgcg gaagcccaga caccaggaag    720

gtgagatctt cgacacagaa aaagagaaat atgagattac ggagcagcgc aagattgatc    780

agaaagctgt ggactcacaa attttaccaa aaatcaaagc tattcctcag ctccagggct    840

acctgcgatc tgtgtttgct ctgacgaatg gaatttatcc tcacaaattg gtgttctaaa    900

tgtcttaaga acctaattaa atagctgact acaaaaaaaa aaaaaaaaaa aaaaag        956


<210>  9006
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  9006

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60


Arg Lys Ala Met 
65


<210>  9007
<211>  687
<212>  DNA
<213>  Homo sapiens

<400>  9007
tgaaaaagtt gagaagccag atactaaaga gaaaaaaaga aggagaaggt tcttgcagct     60

gttacaaaac cagttggtgg tgacaagaac ggcggtaccc gggtggttaa acttcgcaaa    120

atgcctagat agtatcctac tgaagatgtg cctcgaaagc tgttgagcca cggcaaaaaa    180

cccttcagtc agcacgtgag aaaactgcga gccagcatta cccccgggac cattctgatc    240

atcctcactg gacgccacag gggcaagagg gtggttttcc tgaagcagct ggctagtggc    300

ttattacttg tgactggacc tctggtcctc aatcgagttc ctctacgaag aacacaccag    360

aaatttgtca ttgccacctc aaccaaaatc gatatcagca atgtaaaaat cccaaaacat    420

cttactgatg cttacttcaa gaagaagaag ctgcggaagc ccagacacca ggaaggtgag    480

atcttcgaca cagaaaaaga gaaatatgag attacggagc agcgcaagat tgatcagaaa    540

gctgtggact cacaaatttt accaaaaatc aaagctattc ctcagctcca gggctacctg    600

cgatctgtgt ttgctctgac gaatggaatt tatcctcaca aattggtgtt ctaaatgtct    660

taagaaccta attaaatagc tgactac                                        687


<210>  9008
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  9008

Met Leu Thr Ser Arg Arg Arg Ser Cys Gly Ser Pro Asp Thr Arg Lys 
1               5                   10                  15


Val Arg Ser Ser Thr Gln Lys Lys Arg Asn Met Arg Leu Arg Ser Ser 
            20                  25                  30


Ala Arg Leu Ile Arg Lys Leu Trp Thr His Lys Phe Tyr Gln Lys Ser 
        35                  40                  45


Lys Leu Phe Leu Ser Ser Arg Ala Thr Cys Asp Leu Cys Leu Leu 
    50                  55                  60


<210>  9009
<211>  803
<212>  DNA
<213>  Homo sapiens

<400>  9009
ctctttccca tcttgcaaga tggcaggtga aaaagttgag aagccagata ctaaagagaa     60

gaaacccgaa gccaagaagg ttgatgctgg tggcaagaaa ggccatgtag aagaggaagt    120

actcagccgc taaatccaag gttgaaaaga aaaagaagga gaaggttctt gcagctgtta    180

caaaaccagt tggtggtgac aagaacggcg gtacccgggt ggttaaactt cgcaaaatgc    240

ctagatagta tcctactgaa gatgtgcctc gaaagctgtt gagccacggc aaaaaaccct    300

tcagtcagca cgtgagaaaa ctgcgagcca gcattacccc cgggaccatt ctgatcatcc    360

tcactggacg ccacaggggc aagagggtgg ttttcctgaa gcagctggct agtggcttat    420

tacttgtgac tggacctctg gtcctcaatc gagttcctct acgaagaaca caccagaaat    480

ttgtcattgc cacctcaacc aaaatcgata tcagcaatgt aaaaatccca aaacatctta    540

ctgatgctta cttcaagaag aagaagctgc ggaagcccag acaccaggaa ggtgagatct    600

tcgacacaga aaaagagaaa tatgagatta cggagcagcg caagattgat cagaaagctg    660

tggactcaca aattttacca aaaatcaaag ctattcctca gctccagggc tacctgcgat    720

ctgtgtttgc tctgacgaat ggaatttatc ctcacaaatt ggtgttctaa atgtcttaag    780

aacctaatta aatagctgac tac                                            803


<210>  9010
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  9010

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Lys Gly His Val Glu Glu 
            20                  25                  30


Glu Val Leu Ser Arg 
        35


<210>  9011
<211>  671
<212>  DNA
<213>  Homo sapiens

<400>  9011
gctctttccc atcttgcaag atggcaggtg aaaaagttga gaagccagat actaaagaga     60

agaaacccga agccaagaag gttgatgctg gtggcaaggt gaaaaagggt aacctcaaag    120

ctaaaaagcc caagaagggg aagccccatt gcagccgcaa ccctgtcctt gtcagaggaa    180

ttggcaggta ttcccgatct gccatgtatt ccagaaaggc catgtagaag aggaagtact    240

cagccgctaa atccaaggtt ttcctgaagc agctggctag tggcttatta cttgtgactg    300

gacctctggt cctcaatcga gttcctctac gaagaacaca ccagaaattt gtcattgcca    360

cctcaaccaa aatcgatatc agcaatgtaa aaatcccaaa acatcttact gatgcttact    420

tcaagaagaa gaagctgcgg aagcccagac accaggaagg tgagatcttc gacacagaaa    480

aagagaaata tgagattacg gagcagcgca agattgatca gaaagctgtg gactcacaaa    540

ttttaccaaa aatcaaagct attcctcagc tccagggcta cctgcgatct gtgtttgctc    600

tgacgaatgg aatttatcct cacaaattgg tgttctaaat gtcttaagaa cctaattaaa    660

tagctgacta c                                                         671


<210>  9012
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  9012

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60


Arg Lys Ala Met 
65


<210>  9013
<211>  774
<212>  DNA
<213>  Homo sapiens

<400>  9013
tgctctttcc catcttgcaa gatggcaggt gaaaaagttg agaagccaga tactaaagag     60

aagaaacccg aagccaagaa ggttgatgct ggtggcaagg tgaaaaaggg taacctcaaa    120

gctaaaaagc ccaagaaggg gaagccccat tgcagccgca accctgtcct tgtcagagga    180

attggcaggt attcccgatc tgccatgtat tccagaaagg ccatgtagaa gaggaagtac    240

tcagccgcta aatccaaggt tgaaaagaaa aagaaggaga aggttcttgc agctgttaca    300

aaaccagttg gtggtgacat tctgatcatc ctcactggac gccacagggg caagagggtg    360

gttttcctga agcagctggc tagtggctta ttacttgtga ctggacctct ggtcctcaat    420

cgagttcctc tacgaagaac acaccagaaa tttgtcattg ccacctcaac caaaatcgat    480

atcagcaatg taaaaatccc aaaacatctt actgatgctt acttcaagaa gaagaagctg    540

cggaagccca gacaccagga aggtgagatc ttcgacacag aaaaagagaa atatgagatt    600

acggagcagc gcaagattga tcagaaagct gtggactcac aaattttacc aaaaatcaaa    660

gctattcctc agctccaggg ctacctgcga tctgtgtttg ctctgacgaa tggaatttat    720

cctcacaaat tggtgttcta aatgtcttaa gaacctaatt aaatagctga ctac          774


<210>  9014
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  9014

Met Ala Gly Glu Lys Val Glu Lys Pro Asp Thr Lys Glu Lys Lys Pro 
1               5                   10                  15


Glu Ala Lys Lys Val Asp Ala Gly Gly Lys Val Lys Lys Gly Asn Leu 
            20                  25                  30


Lys Ala Lys Lys Pro Lys Lys Gly Lys Pro His Cys Ser Arg Asn Pro 
        35                  40                  45


Val Leu Val Arg Gly Ile Gly Arg Tyr Ser Arg Ser Ala Met Tyr Ser 
    50                  55                  60


Arg Lys Ala Met 
65


<210>  9015
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  9015
gcttgaagtg tttgttctta caataaggtt ctatggagag tagcctgaaa caaagataac     60

tacgggctat gcctgtcaca gtgttcaatt tagtgtgtgt gctgaaaggg ttatttactc    120

ctgatagttt atacaattct caaggatata tttgtttact tttgttttgt tttccaggat    180

tgtttttaaa gtgataagtt aacttttaaa gaagagtaat gtcctgaata tgatgaaaca    240

caaatattta tgctgagcat tctactgaaa cttaactgga caaacaatct caaaaataga    300

caattttcag gttgaatctt ccactttgcc agggtcataa gtgagtagac attttcccta    360

tttggcagga tagtcctcta gaggctgttc acaatggcag ctgtgagggg accttggttt    420

ccttctaagg gctagcgagc tgcctggaac tttccttgaa ggaactcagg attttccttt    480

atttccatgc ttggaggaga ggggattcac aggcccctaa gaggggcctc tgctccatct    540

cactggttgt gaaacaacaa ca                                             562


<210>  9016
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9016

Met Pro Val Thr Val Phe Asn Leu Val Cys Val Leu Lys Gly Leu Phe 
1               5                   10                  15


Thr Pro Asp Ser Leu Tyr Asn Ser Gln Gly Tyr Ile Cys Leu Leu Leu 
            20                  25                  30


Phe Cys Phe Pro Gly Leu Phe Leu Lys 
        35                  40


<210>  9017
<211>  1352
<212>  DNA
<213>  Homo sapiens

<400>  9017
agctcattcc tttgattcta gtctaccagt tgccacttct ggtccatttg catataacac     60

tggagaagtg ttcctttatc tttgtgaagc ccttaacatt caaggagcca ctactgcttc    120

tatgctgctg aaaaatacaa gacactgcct ctacctctgc atctgtcctt tgctttttgc    180

ttggaaacta tcacatcaaa tcacactgag atcagttcct actgagctct cactggcaaa    240

ctatcagtag aagaagcctg gacaaaactg agttcaatgc ttcacaattg ctgcgctctt    300

cttctcccca gtggaaaaaa aaatgctctc tgcaccacat ggccgctggc cgctgccaga    360

ggatggagga aggggtgatg ttggtcattc aagactgttt ttcctacctc ttcagtgcct    420

ctttcaactg tatgaagtta aaaccagctt ggcaggctct agagagactg acctctgcag    480

atggtttaaa gggagaagct caagggtcca cagttcacag ggctgccaat caggcctgtg    540

cagaaaactc aacagtctaa aagaatatat gaagacagaa cctcaaccta gaagaaatgg    600

acaaattccc agacacatca aggaattcct agacaaacta tcaaaactga atcatgatta    660

gatagaaaat ctgaacagat caatataagt aaagagatta aagcagtaat aaactctccc    720

atcaaagaaa agctcaggac ctgatggctt cactgctgaa ttctaccaaa cgtttaaaga    780

actaacacca atgattctca aactcttttt aaaaattgaa gatgagagaa cacttccaaa    840

ttcatatcac gaggccagca ttaccctgat accaacgcca gacaaagaca ctataagaaa    900

aggcaattat ggaccaatat ccctgataaa catggatgta aaaatcctca tcaaaatact    960

agcaaatgaa attcaaccac aaatttaaaa aagcattcac catgatcgag tgggatttat   1020

ccctgggatg caggaagttt caacatacac aaatccataa acatgataca ccacatcaac   1080

aagatgaagg acaaaatctt tataatctca atagatgcag gaaaagcatt taacagaatt   1140

cagcaccctt tcatgattta aaaaaactca acaaaatata gaaggactgt accccaacac   1200

aataaagacc agatatgaca aacccacagc taacattctc aacagtgaaa agttaaaagc   1260

ttttcttctg agatcaggaa caagacaata atgctcactc tctcgacttc tgttcatcgt   1320

aacgttggaa gttctagaca gagcaattag ac                                 1352


<210>  9018
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  9018

Met Leu Ser Ala Pro His Gly Arg Trp Pro Leu Pro Glu Asp Gly Gly 
1               5                   10                  15


Arg Gly Asp Val Gly His Ser Arg Leu Phe Phe Leu Pro Leu Gln Cys 
            20                  25                  30


Leu Phe Gln Leu Tyr Glu Val Lys Thr Ser Leu Ala Gly Ser Arg Glu 
        35                  40                  45


Thr Asp Leu Cys Arg Trp Phe Lys Gly Arg Ser Ser Arg Val His Ser 
    50                  55                  60


Ser Gln Gly Cys Gln Ser Gly Leu Cys Arg Lys Leu Asn Ser Leu Lys 
65                  70                  75                  80


Glu Tyr Met Lys Thr Glu Pro Gln Pro Arg Arg Asn Gly Gln Ile Pro 
                85                  90                  95


Arg His Ile Lys Glu Phe Leu Asp Lys Leu Ser Lys Leu Asn His Asp 
            100                 105                 110


<210>  9019
<211>  786
<212>  DNA
<213>  Homo sapiens

<400>  9019
cctctactac tgtgcataaa acttgaagag ttggaggcca tgttcaccag cccagaagat     60

atacgtacac ttgggatttt tgagttgtgt ggtggacgga ggggttagtc ttaaacacta    120

ctgatgaacc tatgtgattg ctgcctgttt cccgccaaat aacagggcag tcacggctta    180

tcctttctgg ctcccctttt accaccttct cctggaattt acctgacctc ctcttctcac    240

agcttggcag gctctagaga gactgacctc tgcagatggt ttaaagggag aagctcaagg    300

gtccacagtt cacagggctg ccaatcaggc ctgtgcagaa aactcaacag tctaaaagaa    360

tatatgaaga cagaacctca acctagaaga aatggacaaa ttcccagaca catcaaggaa    420

ttcctagaca aactatcaaa actgaatcat gattagatag aaaatctgaa cagatcaata    480

taagtaaaga gattaaagca gtaataaact ctcccatcaa agaaaagctc aggacctgat    540

ggcttcactg ctgaattcta ccaaacgttt aaagaactaa caccaatgat tctcaaactc    600

tttttaaaaa ttgaagatga gagaacactt ccaaattcat atcacgaggc cagcattacc    660

ctgataccaa cgccagacaa agacactata agaaaaggca attatggacc aatatccctg    720

ataaacatgg atgtaaaaat cctcatcaaa atactagcaa atgaaattca accacaaatt    780

taaaaa                                                               786


<210>  9020
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  9020

Met Ile Leu Lys Leu Phe Leu Lys Ile Glu Asp Glu Arg Thr Leu Pro 
1               5                   10                  15


Asn Ser Tyr His Glu Ala Ser Ile Thr Leu Ile Pro Thr Pro Asp Lys 
            20                  25                  30


Asp Thr Ile Arg Lys Gly Asn Tyr Gly Pro Ile Ser Leu Ile Asn Met 
        35                  40                  45


Asp Val Lys Ile Leu Ile Lys Ile Leu Ala Asn Glu Ile Gln Pro Gln 
    50                  55                  60


Ile 
65


<210>  9021
<211>  572
<212>  DNA
<213>  Homo sapiens

<400>  9021
attatgttcc tgctgatggc agaagtgcaa aagagtgagg agaagccccc agtgctctta     60

aagcctcagc ctaggactgt cacctctgct tagcttacta tcagtggggt gaggaaatat    120

acatcacctt ttgtggaagg aacgtcaagg tcatacagct aaagatgtgg agacagggaa    180

aggacggaaa ttgctttcat ctttcaaagt aaagccatgg agagaaggct ggatcaacca    240

gggtgttgag atattagaga aaatctcagt ctttcaatga gagggacaat tgaagaagtt    300

tcccaggctg catcaactgc aacgccattg tgtcacctgc agaagttagc tgcacctcat    360

gctgctgctg tccatgctga ctgcagtccc ctgggcatgt ttacgttttg tctaagttct    420

tagcactgat tttttctggc attcaggttt cacatctgta accgctcttg ccagaggtag    480

aagctttgtt gagattgagg actatgctgg acacacagta attccattat caccagatta    540

attcgtaatg aatgaacaca tgacgctctg ct                                  572


<210>  9022
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  9022

Met Arg Gly Thr Ile Glu Glu Val Ser Gln Ala Ala Ser Thr Ala Thr 
1               5                   10                  15


Pro Leu Cys His Leu Gln Lys Leu Ala Ala Pro His Ala Ala Ala Val 
            20                  25                  30


His Ala Asp Cys Ser Pro Leu Gly Met Phe Thr Phe Cys Leu Ser Ser 
        35                  40                  45


<210>  9023
<211>  920
<212>  DNA
<213>  Homo sapiens

<400>  9023
cctggagcca cacccaactg agatcagcag agtggcccta cttgatccat agacacaccg     60

atggaatctc actctgtcac ccaggctgga gtgcagtggc actatcttgg ctcactgcag    120

cttccgcttc ccgggttcaa gcaattctcc tgcctcaacc tcccaagtag ctggggttac    180

agatgagcta cttaacagcc acagccctcc gactttggaa tagccctgcc tgccatcatc    240

atctgtcctg agaggaaggc ttgcctttga aattccttta ttgtagcaga catttgctgc    300

taggtctctt ttgttagtgc acatgcctgc tcttcagcct gcctgtgttc ctgcacccat    360

atttctgtgt gtctgcccct ctccccacct tgcctagcct tctattctag tgtttgcact    420

tttccaggat cctggaattt gttctgttgc tttaacttgc tttcctgtgg ctgagctcca    480

ctggctcctg actgcctgct tggtttgtct gccagcttgc cttacccttg ggcttcaatc    540

ttcacaatcc tcataatctt gctctgagca tagggtacca tgcagcccaa ttctacgtgg    600

ttcatctgct cctgacttaa ctgaatctac ctcttacttg agccccttat attaaagagg    660

gtcgatggct tttataatga aagtgactgc aatacaaata cattttaatg gtgtcacaac    720

ctttaaacat tagcagtcca ggttgttcaa ggaccacctt aagttctgaa cttagtgtgt    780

agaaaagttt ccacaagtaa aaaatatttt catgcttctg aatattttat gggttttgtc    840

ctacatagga atacttgcta tctttattga aaggggtatg tggaatcaaa tatctgaata    900

aattatgtca tatatataca                                                920


<210>  9024
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9024

Met Glu Ser His Ser Val Thr Gln Ala Gly Val Gln Trp His Tyr Leu 
1               5                   10                  15


Gly Ser Leu Gln Leu Pro Leu Pro Gly Phe Lys Gln Phe Ser Cys Leu 
            20                  25                  30


Asn Leu Pro Ser Ser Trp Gly Tyr Arg 
        35                  40


<210>  9025
<211>  2311
<212>  DNA
<213>  Homo sapiens

<400>  9025
ctgtgtggaa cttgggattc gaacggcagg cgggaagtgc tctagcaggg gagtctgacc     60

ttgtgaggga atacctgtgt cccccctttt ttcccctttt tacccaataa aaccctgcct    120

tactcaccct ttaaatcatc tgcgagcctg aattttcatg gccgtgggac ggacaagaac    180

tttatcttca gctgaactaa gaaaaagtcc tgcaacattt ttggcgcgca atgtgggggc    240

accagaagcg ggcaccgttg agctgttgca actgttctgc tggagcctta tgtatgtggt    300

tgaaaccacc tgtactactg gaatgaaagc acctttacag aagaggcaat gcaagttgta    360

ttcatcacat gtgtagaatg aattaagatt tatgccagtt gcaaagaaga atattggctc    420

actatttttc ctctgggcat gggtacaagc aattttccag tcttgaccct ttatctgttg    480

accaagctaa ggcagaaacc agctaaattc tggatttaat cttgagcagc aaaaaagatc    540

agcttttgaa gtggatctgc ttttattctt ggcaaaagtt cagcggagac caaccagagt    600

ggtgacaaag ttcttcaaca tcaagccaaa tgtaatacaa ggaattacgg atagtgctta    660

atctaaaata aagaaattcc acatctccct aaaaagttat tggcttcaag aatgaaaaca    720

aaagaagcat atttgtctca atccaaacac agacaccaga aagacaaacc aggagtatac    780

agcaaagtag cttgcaggat aatacattga aaaatgtaat tgtgcataaa tcatgcacaa    840

agtagaaacc acaaattctg tatttggcaa ggcttcggtt cctttgcata attctttcat    900

tttcatcttg ctgcttccat tctcttttca tcaaaaaaag ctacataaaa caaagacata    960

aactgtatgc aattaaaatg agaaaatagc tgaaaggaat gtattgataa ttatgttaaa   1020

atctatacca taagtattct tgcattgtta agcatctaat ttttcatgtg ttgacatcag   1080

catctcagtt ctctctaaca tctgaaagct ttttttttta aggcaacttc ttttagagtg   1140

aacaaactta tgtaccaccg agttgacaaa agtataacta tatcctacag aaagagacct   1200

caagtaaacc tccagcagcc atctggactt ccatgaaaac agaacaatca gtgagatgca   1260

gagcttggag gagacagttt ccatagactg aagcacgtgc tgaagcaaag ttcacacttg   1320

caggattaga agaggttgac cgaaagaagg aaggacatgg acagctatgt tgttgtggag   1380

tcctgtttta tagtcataac cttgagtcaa gtgagtttgt ctggacagac agagcttgtt   1440

gcctttactt atagggaagg caccggacac agacagcctc aaggacattt gttctagcct   1500

ttcagtatcc tttctcttaa ttatctcacc tcatccatga agctggtatg tacgattttt   1560

cctttctttc tcaatccttt aaaaaattaa agctctaaat ctcatttcca cttagatttt   1620

aatgttgcat tgtaacttaa gataaaacct tgctctgatg ttaaaaatac taaagtaaga   1680

agcaatatgg catagtgctt atgagcagga ctacatagtt ctttctgaat acaaatctca   1740

gataaaacac tatctcagtg atcaaccagg ttaagcaacc tttttagtgc ctcaattatt   1800

ccatttgtaa aattgtaata atgatagtac taacctataa gattgtggtg aggattaagt   1860

cagataatac aaaagaagca tttagagtat ttcctggcat tatctaccat ttattgaatt   1920

tttatggtta agaagaataa ggaaaagcag aagaaaagga aaagagaaaa aatacataag   1980

aagaaggaag agtggtaagc tctagtaaat tacaacaaac ggtaacgtag aaaacatttg   2040

ttagccctta atataggcca ggcactgtgt tcaatgctta aacctcatta ctgttctttg   2100

aagtggataa cattattcct tccattttaa agaaaggaat actaaagaca actttgtcaa   2160

tattattcat gtaataaatg acagaatttg accaagacaa tagagaatga actcttaatc   2220

actatattgt tttatttttt gaaaatagat tttaagttct tattaaatgt taatgactca   2280

catcaaaata aagccaatca aaattgacag c                                  2311


<210>  9026
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  9026

Met Ala Val Gly Arg Thr Arg Thr Leu Ser Ser Ala Glu Leu Arg Lys 
1               5                   10                  15


Ser Pro Ala Thr Phe Leu Ala Arg Asn Val Gly Ala Pro Glu Ala Gly 
            20                  25                  30


Thr Val Glu Leu Leu Gln Leu Phe Cys Trp Ser Leu Met Tyr Val Val 
        35                  40                  45


Glu Thr Thr Cys Thr Thr Gly Met Lys Ala Pro Leu Gln Lys Arg Gln 
    50                  55                  60


Cys Lys Leu Tyr Ser Ser His Val 
65                  70


<210>  9027
<211>  581
<212>  DNA
<213>  Homo sapiens

<400>  9027
aaaggtagga atcgtaagag tgtacagaaa taagtcacat gcagaccata ttgaaatacg     60

cagagaattc catggagact ctgatggcta gggcaccgtt gagctgttgc aactgttctg    120

ctggagcctt atgtatgtgg ttgaaaccac ctgtactact ggaatgaaag cacctttaca    180

gaagaggcaa tgcaagttgt attcatcaca tgtgtagaat gaattaagat ttatgccagt    240

tgcaaagaag aatattggct cactattttt cctctgggca tgggtacaag caattttcca    300

gtcttgaccc tttatctgtt gaccaagcta aggcagaaac cagctaaatt ctggatttaa    360

tcttgagcag caaaaaagat cagcttttga agtggatctg cttttattct tggcaaaagt    420

tcagcggaga ccaaccagag tggtgacaaa gttcttcaac atcaagccaa atgtaataca    480

aggaattacg gatagtgctt aatctaaaat aaagaaattc cacatctccc taaaaagtta    540

ttggcttcaa gaatgaaaac aaaagaagca tatttgtctc a                        581


<210>  9028
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  9028

Met Gln Thr Ile Leu Lys Tyr Ala Glu Asn Ser Met Glu Thr Leu Met 
1               5                   10                  15


Ala Arg Ala Pro Leu Ser Cys Cys Asn Cys Ser Ala Gly Ala Leu Cys 
            20                  25                  30


Met Trp Leu Lys Pro Pro Val Leu Leu Glu 
        35                  40


<210>  9029
<211>  625
<212>  DNA
<213>  Homo sapiens

<400>  9029
gtggaacttg ggattcgaac ggcaggcggg aagtgctcta gcaggggagt ctgaccttgt     60

gagggaatac ctgtgtcccc ccttttttcc cctttttacc caataaaacc ctgccttact    120

caccctttaa atcatctgcg agcctgaatt ttcatggccg tgggacggac aagaacttta    180

tcttcagctg aactaagaaa aagtcctgca acatttttgg cgcgcaatgt gggggcacca    240

gaagcgggca ccgttgagct gttgcaactg ttctgctgga gccttatgta tgtggttgaa    300

accacctgta ctactggaat gaaagcacct ttacagaaga ggcaatgcaa gttgtattca    360

tcacatgtgt agaatgaatt aagatttatg ccagttgcaa agaagaatat tggctcacta    420

tttttcctct gggcatgtgg aaatgtaaat cagtccatgt tactcacctc ggagaagcag    480

aagtacgatt tactattgtt gcttgcttac ttactcttat caatttctat gagaggggta    540

caagcaattt tccagtcttg accctttatc tgttgaccaa gctaaggcag aaaccagcta    600

aattctggat ttaatcttga gcagc                                          625


<210>  9030
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  9030

Met Ala Val Gly Arg Thr Arg Thr Leu Ser Ser Ala Glu Leu Arg Lys 
1               5                   10                  15


Ser Pro Ala Thr Phe Leu Ala Arg Asn Val Gly Ala Pro Glu Ala Gly 
            20                  25                  30


Thr Val Glu Leu Leu Gln Leu Phe Cys Trp Ser Leu Met Tyr Val Val 
        35                  40                  45


Glu Thr Thr Cys Thr Thr Gly Met Lys Ala Pro Leu Gln Lys Arg Gln 
    50                  55                  60


Cys Lys Leu Tyr Ser Ser His Val 
65                  70


<210>  9031
<211>  564
<212>  DNA
<213>  Homo sapiens

<400>  9031
agcaggggag tctgaccttg tgagggaata cctgtgtccc cccttttttc ccctttttac     60

ccaataaaac cctgccttac tcacccttta aatcatctgc gagcctgaat tttcatggcc    120

gtgggacgga caagaacttt atcttcagct gaactaagaa aaagtcctgc aacatttttg    180

gcgcgcaatg tgggggcacc agaagcgggc accgttgagc tgttgcaact gttctgctga    240

tttctatcat ggaaaatatc cctgcaagca gtaaccacta tttgaatggt gaaatcagca    300

gcacagcaaa catggttctt aatgaggagc cttatgtatg tggttgaaac cacctgtact    360

actggaatga aagcaccttt acagaagagg caatgcaagt tgtattcatc acatgtgtag    420

aatgaattaa gatttatgcc agttgcaaag aagaatattg gctcactatt tttcctctgg    480

gcatgggtac aagcaatttt ccagtcttga ccctttatct gttgaccaag ctaaggcaga    540

aaccagctaa attctggatt taat                                           564


<210>  9032
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  9032

Met Val Lys Ser Ala Ala Gln Gln Thr Trp Phe Leu Met Arg Ser Leu 
1               5                   10                  15


Met Tyr Val Val Glu Thr Thr Cys Thr Thr Gly Met Lys Ala Pro Leu 
            20                  25                  30


Gln Lys Arg Gln Cys Lys Leu Tyr Ser Ser His Val 
        35                  40


<210>  9033
<211>  570
<212>  DNA
<213>  Homo sapiens

<400>  9033
gggagtctga ccttgtgagg gaatacctgt gtcccccctt ttttcccctt tttacccaat     60

aaaaccctgc cttactcacc ctttaaatca tctgcgagcc tgaattttca tggccgtggg    120

acggacaaga actttatctt cagctgaact aagaaaaagt cctgcaacat ttttggcgcg    180

caatgtgggg gcaccagaag cgggcaccgt tgagctgttg caactgttct gctggagcct    240

tatgtatgtg gttgaaacca cctgtactac tggaatgaaa gcacctttac agaagaggca    300

atgcaagttg tattcatcac atgtgtagaa tgaattaaga tttatgccag ttgcaaagaa    360

gaatattggc tcactatttt tcctctgggc atcagcatat gatcccctgt tgaagacaga    420

caagtacatc tttctggtgg ctcctagacc tggcattggg aacagaagat tatcagtatg    480

atccgtacgc ttaaggaaag atctcatatt attgaaatga atattttatt tgataaattg    540

aactacagaa taaagtactt ttaacaaacc                                     570


<210>  9034
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  9034

Met Ala Val Gly Arg Thr Arg Thr Leu Ser Ser Ala Glu Leu Arg Lys 
1               5                   10                  15


Ser Pro Ala Thr Phe Leu Ala Arg Asn Val Gly Ala Pro Glu Ala Gly 
            20                  25                  30


Thr Val Glu Leu Leu Gln Leu Phe Cys Trp Ser Leu Met Tyr Val Val 
        35                  40                  45


Glu Thr Thr Cys Thr Thr Gly Met Lys Ala Pro Leu Gln Lys Arg Gln 
    50                  55                  60


Cys Lys Leu Tyr Ser Ser His Val 
65                  70


<210>  9035
<211>  398
<212>  DNA
<213>  Homo sapiens

<400>  9035
aatcgtaaga gtgtacagaa ataagtcaca tgcagaccat attgaaatac gcagagaatt     60

ccatggagac tctgatggct agggcaccgt tgagctgttg caactgttct gctgatttct    120

atcatggaaa atatccctgc aagcagtaac cactatttga atggtgaaat cagcagcaca    180

gcaaacatgg ttcttaatga gattgttttg catttaaaaa ttttatgcac caggcatttt    240

acaatgcaaa tgatcttgct ttttaagcca atattatcct tttaagataa ttttgataat    300

gtagatatcg ttcatcgtgt tttgatataa gttttaatca ggcaatattt caattagata    360

gaagtatgta caaaagtaat aaactatatc tctgaatg                            398


<210>  9036
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  9036

Met Glu Asn Ile Pro Ala Ser Ser Asn His Tyr Leu Asn Gly Glu Ile 
1               5                   10                  15


Ser Ser Thr Ala Asn Met Val Leu Asn Glu Ile Val Leu His Leu Lys 
            20                  25                  30


Ile Leu Cys Thr Arg His Phe Thr Met Gln Met Ile Leu Leu Phe Lys 
        35                  40                  45


Pro Ile Leu Ser Phe 
    50


<210>  9037
<211>  775
<212>  DNA
<213>  Homo sapiens

<400>  9037
ccttgtgagg gaatacctgt gtcccccctt ttttcccctt tttacccaat aaaaccctgc     60

cttactcacc ctttaaatca tctgcgagcc tgaattttca tggccgtggg acggacaaga    120

actttatctt cagctgaact aagaaaaagt cctgcaacat ttttggcgcg caatgtgggg    180

gcaccagaag cgggcaccgt tgagctgttg caactgttct gctgctgagg aaaccaaatc    240

tgaaagagat taagaaacat gagcagtatc aaatgactag acaatgtctc agctgaattc    300

aatcatcttt ttaaactcca tctacctgct ctatctgaca ttaataaaca ttccaagaag    360

aatgtctgca aagaggagag actgagaatt actagccact caattaggtc acttaacatc    420

ttatattagc tgctcatttc atttgggagc aaggagaact gggttctcat tcttcagcca    480

atgagctgga gaaacctgga caaataattt aattgcttga ggcttaattg tccaatcact    540

gaaatgtaag aaaataagaa ataatcttta aatttacttt caattaaata aaacactgat    600

tgttaataca tatttgaaaa tatactagaa actgaacgtg caaattagga taatgaattg    660

cactctaaat ttaaaatgca agaaatgatg tattttattt cttatttata catatatatt    720

atttcaagaa ttataaatct caacatgctt tccatataat aaaaatgttt aatat         775


<210>  9038
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  9038

Met Ala Val Gly Arg Thr Arg Thr Leu Ser Ser Ala Glu Leu Arg Lys 
1               5                   10                  15


Ser Pro Ala Thr Phe Leu Ala Arg Asn Val Gly Ala Pro Glu Ala Gly 
            20                  25                  30


Thr Val Glu Leu Leu Gln Leu Phe Cys Cys 
        35                  40


<210>  9039
<211>  954
<212>  DNA
<213>  Homo sapiens

<400>  9039
acggcaggcg ggaagtgctc tagcagggga gtctgacctt gtgagggaat acctgtgtcc     60

cccctttttt ccccttttta cccaataaaa ccctgcctta ctcacccttt aaatcatctg    120

cgagcctgaa ttttcatggc cgtgggacgg acaagaactt tatcttcagc tgaactaaga    180

aaaagtcctg caacattttt ggcgcgcaat gtgggggcac cagaagcgaa agaacacccc    240

ctcttaaaca tggagatcgt tatatagaat gtccaaggca aattaaggaa aataattatt    300

gtagctgatg aagcagaaac cctattagag ctaaatgcta cttcacagta ctcagtggtg    360

gaggttctga aggcaccgtt gagctgttgc aactgttctg ctgctgagga aaccaaatct    420

gaaagagatt aagaaacatg agcagtatca aatgactaga caatgtctca gctgaattca    480

atcatctttt taaactccat ctacctgctc tatctgacat taataaacat tccaagaaga    540

atgtctgcaa agaggagaga ctgagaatta ctagccactc aattaggtca cttaacatct    600

tatattagct gctcatttca tttgggagca aggagaactg ggttctcatt cttcagccaa    660

tgagctggag aaacctggac aaataattta attgcttgag gcttaattgt ccaatcactg    720

aaatgtaaga aaataagaaa taatctttaa atttactttc aattaaataa aacactgatt    780

gttaatacat atttgaaaat atactagaaa ctgaacgtgc aaattaggat aatgaattgc    840

actctaaatt taaaatgcaa gaaatgatgt attttatttc ttatttatac atatatatta    900

tttcaagaat tataaatctc aacatgcttt ccatataata aaaatgttta atat          954


<210>  9040
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9040

Met Ala Val Gly Arg Thr Arg Thr Leu Ser Ser Ala Glu Leu Arg Lys 
1               5                   10                  15


Ser Pro Ala Thr Phe Leu Ala Arg Asn Val Gly Ala Pro Glu Ala Lys 
            20                  25                  30


Glu His Pro Leu Leu Asn Met Glu Ile Val Ile 
        35                  40


<210>  9041
<211>  128
<212>  DNA
<213>  Homo sapiens

<400>  9041
aatatatagt gtttccttat aaaatgtatc agagatgtca catataaata tgagctagtg     60

aaataacttt cacgtctttc tctcttttac acacacacac accccatgta tatgcctaaa    120

acacactg                                                             128


<210>  9042
<211>  399
<212>  DNA
<213>  Homo sapiens

<400>  9042
tgaggacaga aaaggctttc taaaatgaga cataaaaagc acaaaccatt gaagaaaaga     60

cagataaatt caactatatt tcaaaagcac cacaaagaga gtgaaaatac agaaaaagaa    120

cttatttttc taacacatgt gggaaaagac gagattccag gaagtataaa gtataaacat    180

taagaaaaag atgaacaacc caatagaaaa actgcataag atcttaacgt agcctttaca    240

aaagagcaaa tctggccggg cacaggtatg aacatgaggt tagaaataaa agatgacagt    300

ttttttaatg acaactgctc tattccaaga cagtctgcat aaagttacta attactctga    360

tgtttaaaag tctgtaagag gtggccgggc atggtggct                           399


<210>  9043
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  9043

Met Arg His Lys Lys His Lys Pro Leu Lys Lys Arg Gln Ile Asn Ser 
1               5                   10                  15


Thr Ile Phe Gln Lys His His Lys Glu Ser Glu Asn Thr Glu Lys Glu 
            20                  25                  30


Leu Ile Phe Leu Thr His Val Gly Lys Asp Glu Ile Pro Gly Ser Ile 
        35                  40                  45


Lys Tyr Lys His 
    50


<210>  9044
<211>  3492
<212>  DNA
<213>  Homo sapiens

<400>  9044
atggcttcca gtccgctgcc agggcccaac gacatcctgc tggcgtcgcc gtcgagcgcc     60

ttccagcccg acacgctgag ccagccgcgg ccagggcacg ccaacctcaa acccaaccag    120

gtgggccagg tgatcctcta cggcattccc atcgtgtcgt tggtgatcga cgggcaagag    180

cgcctgtgcc tggcgcagat ctccaacact ctgctcaaga acttcagcta caacgagatc    240

cacaaccgtc gcgtggcact gggcatcacg tgtgtgcagt gcacgccggt gcaactggag    300

atcctgcggc gtgccggggc catgcccatc tcatcgcgcc gctgcggcat gatcaccaaa    360

cgcgaggccg agcgtctgtg caagtcgttc ctgggcgaaa acaggccgcc caagctgcca    420

gacaatttcg ccttcgacgt gtcacacgag tgcgcctggg gctgccgcgg cagcttcatt    480

cccgcgcgct acaacagctc gcgcgccaag tgcatcaaat gcagctactg caacatgtac    540

ttctcgccca acaagttcat tttccactcc caccgcacgc ccgacgccaa gtacactcag    600

ccagacgcag ccaacttcaa ctcgtggcgc cgtcatctca agctcaccga caagagtccc    660

caggacgagc tggtcttcgc ctgggaggac gtcaaggcca tgttcaacgg cggcagccgc    720

aagcgcgcac tgccccagcc gggcgcgcac cccgcctgcc acccgctcag ctctgtgaag    780

gcggccgccg tggccgccgc ggccgcggtg gccggaggcg ggggtctgct gggcccccac    840

ctgctgggtg cgcccccgcc gccgccgccg ccaccgccgc ccttggcaga gctggctggt    900

gccccgcacg cccatcacaa gcggccgcgc ttcgacgacg acgacgactc cttgcaggag    960

gccgccgtag tggccgccgc cagcctctcg gccgcagccg ccagcctctc tgtggctgct   1020

gcttcgggcg gggccaaagg cccgcgcagc tacccagtca tcccggtgcc cagcaagggc   1080

tcgttcgggg gcgtcctgca gaagttcccg ggctgcggcg ggctcttccc gcacccctac   1140

accttccctg ccgcggccgc cgccttcagc ttgtgccata agaaagagga tgcgggtgcc   1200

gccgctgagg ccctgggggg cgcgggcgca ggcggcgcgg gcgcggcgcc caaggccggc   1260

ttgtccggcc tcttctggcc cgcgggccgc aaggacgcct tctatccgcc cttctgcatg   1320

ttctggccgc cgcggacccc tggcgggctc ccggtgccca cctacctgca gcccccgcct   1380

cagccgccct cggcgctagg ctgcgcgcta ggcgaaagcc cggccctgct gcgccaggcc   1440

ttcctggacc tggctgagcc aggcggtgct gctgggagcg ccgaggccgc gcccccgccg   1500

gggcagcccc cgcaggtagt ggccaacggc ccgggctccg gcccacctcc tcctgccggg   1560

ggcgccggct ctcgcgacgc gctcttcgag tcgcccccgg gcggcagcgg cggggactgc   1620

agcgcgggct ccacgccgcc cgcggactct gtggcagctg ccggggcagg ggccgcggcc   1680

gccgggtctg gccccgcggg ctcccgggtt ccggcgcccc accatccgca ccttctggag   1740

gggcgcaaag cgggcggtgg cagctaccac cattccagcg ccttccggcc agtgggcggc   1800

aaggacgacg cggagagcct ggccaagctg cacggggcgt cggcgggcgc gccccactcg   1860

gcccagacct gctgctaccc cagcgaggac agctccgagg acgaggacga cgaggaagaa   1920

gagcaggagg tggacgtgga gggccacaag ccccccgagg tcgggggcgg ccggttcctc   1980

cagggccgag ggccgtcgga gaaggggagc agccgggacc gcgcgccggc cgtcgcgggc   2040

gcgttcccgc tcggcctgaa ctcctccagg ctgctgcagg aagacgggaa actcggggac   2100

cccggctcgg acctgccccc gcccccgccg ccgcccctgg ccccccagaa ggcgagtggc   2160

ggcggcagca gcagcccggg cagcccagtt caccatccat cactggagga gcagccctcc   2220

tacaaagata gtcagaaaac taaggaaaat aaccaagtaa ttgtatctac aaaggatgac   2280

aacagctttt cagataagaa caaggagcat agctttttca tcacagactc tgatgcttct   2340

ggaggagatt tttggagaga aagatcaggt gaacatacac aagaaaccaa ctcacctcat   2400

tcactgaaaa aggatgtaga aaatatgggg aaagaagaac ttcagaaggt tttatttgaa   2460

caaatagatt tacggagacg actggaacaa gaattccagg tgttaaaagg aaacacatct   2520

ttcccagtat tcatttacca ccctggtcaa aggcatcttg gatccctaga ggctcagagg   2580

aaagttttct tcttcacaaa gggagccatg cttgccatgt gctccagtgt ctggaaccac   2640

actgatcttc ctggaggcct gcgggccaca gcgcaggacc aagtgttgga accagggcag   2700

tttgtggagg gctggttccc ctgttgccct gtacccttag acccacctct agagcatcct   2760

gacctgaatg ctgttctcca cgtgtctgct caagcagctc tcccctctaa tgttcccaga   2820

atgaatgaca gctcttctct caatctttgc atggcaccac atacttccct ctattacagt   2880

gactttgaca tcaaaatcag agatccccta tgcagcaagt ttgatcagga aagaaaagct   2940

tggcgcccat ctcagcaaaa gctaaaagat tttctgctct ttatggttct gacaccccag   3000

ttactgcccc aaggaaacca aagtgtcagc agtcatcctc agggtgtctc atctctgtct   3060

ctccttcgct tccaaaaagc ctgcctgaaa tctgactttc agagagttac tgcaggtgaa   3120

aggggccacg ttcatgaaag ccagcccaag accacatgtc ttccagtagt gttgctgata   3180

gagcccatcg taggccttcc tacttactgt gatgttaaat ccaagtccac aagatcatat   3240

tatgccccaa attctgcttt tcagatgaga gagttaaata gtgaacactt tgcagccaag   3300

atttctaagt atacgcaggt gaagatacgg aaaggggatg aacctgaact tggctggctt   3360

tccaggactc aacgccatgt ggaagctgcc agggcttggg gctttccccc tctgaagcca   3420

caccctgagc tctacgttgg ccgctttcag acatggctgg ggcggctggg acacagggca   3480

ccaagtccct ag                                                       3492


<210>  9045
<211>  1163
<212>  PRT
<213>  Homo sapiens

<400>  9045

Met Ala Ser Ser Pro Leu Pro Gly Pro Asn Asp Ile Leu Leu Ala Ser 
1               5                   10                  15


Pro Ser Ser Ala Phe Gln Pro Asp Thr Leu Ser Gln Pro Arg Pro Gly 
            20                  25                  30


His Ala Asn Leu Lys Pro Asn Gln Val Gly Gln Val Ile Leu Tyr Gly 
        35                  40                  45


Ile Pro Ile Val Ser Leu Val Ile Asp Gly Gln Glu Arg Leu Cys Leu 
    50                  55                  60


Ala Gln Ile Ser Asn Thr Leu Leu Lys Asn Phe Ser Tyr Asn Glu Ile 
65                  70                  75                  80


His Asn Arg Arg Val Ala Leu Gly Ile Thr Cys Val Gln Cys Thr Pro 
                85                  90                  95


Val Gln Leu Glu Ile Leu Arg Arg Ala Gly Ala Met Pro Ile Ser Ser 
            100                 105                 110


Arg Arg Cys Gly Met Ile Thr Lys Arg Glu Ala Glu Arg Leu Cys Lys 
        115                 120                 125


Ser Phe Leu Gly Glu Asn Arg Pro Pro Lys Leu Pro Asp Asn Phe Ala 
    130                 135                 140


Phe Asp Val Ser His Glu Cys Ala Trp Gly Cys Arg Gly Ser Phe Ile 
145                 150                 155                 160


Pro Ala Arg Tyr Asn Ser Ser Arg Ala Lys Cys Ile Lys Cys Ser Tyr 
                165                 170                 175


Cys Asn Met Tyr Phe Ser Pro Asn Lys Phe Ile Phe His Ser His Arg 
            180                 185                 190


Thr Pro Asp Ala Lys Tyr Thr Gln Pro Asp Ala Ala Asn Phe Asn Ser 
        195                 200                 205


Trp Arg Arg His Leu Lys Leu Thr Asp Lys Ser Pro Gln Asp Glu Leu 
    210                 215                 220


Val Phe Ala Trp Glu Asp Val Lys Ala Met Phe Asn Gly Gly Ser Arg 
225                 230                 235                 240


Lys Arg Ala Leu Pro Gln Pro Gly Ala His Pro Ala Cys His Pro Leu 
                245                 250                 255


Ser Ser Val Lys Ala Ala Ala Val Ala Ala Ala Ala Ala Val Ala Gly 
            260                 265                 270


Gly Gly Gly Leu Leu Gly Pro His Leu Leu Gly Ala Pro Pro Pro Pro 
        275                 280                 285


Pro Pro Pro Pro Pro Pro Leu Ala Glu Leu Ala Gly Ala Pro His Ala 
    290                 295                 300


His His Lys Arg Pro Arg Phe Asp Asp Asp Asp Asp Ser Leu Gln Glu 
305                 310                 315                 320


Ala Ala Val Val Ala Ala Ala Ser Leu Ser Ala Ala Ala Ala Ser Leu 
                325                 330                 335


Ser Val Ala Ala Ala Ser Gly Gly Ala Lys Gly Pro Arg Ser Tyr Pro 
            340                 345                 350


Val Ile Pro Val Pro Ser Lys Gly Ser Phe Gly Gly Val Leu Gln Lys 
        355                 360                 365


Phe Pro Gly Cys Gly Gly Leu Phe Pro His Pro Tyr Thr Phe Pro Ala 
    370                 375                 380


Ala Ala Ala Ala Phe Ser Leu Cys His Lys Lys Glu Asp Ala Gly Ala 
385                 390                 395                 400


Ala Ala Glu Ala Leu Gly Gly Ala Gly Ala Gly Gly Ala Gly Ala Ala 
                405                 410                 415


Pro Lys Ala Gly Leu Ser Gly Leu Phe Trp Pro Ala Gly Arg Lys Asp 
            420                 425                 430


Ala Phe Tyr Pro Pro Phe Cys Met Phe Trp Pro Pro Arg Thr Pro Gly 
        435                 440                 445


Gly Leu Pro Val Pro Thr Tyr Leu Gln Pro Pro Pro Gln Pro Pro Ser 
    450                 455                 460


Ala Leu Gly Cys Ala Leu Gly Glu Ser Pro Ala Leu Leu Arg Gln Ala 
465                 470                 475                 480


Phe Leu Asp Leu Ala Glu Pro Gly Gly Ala Ala Gly Ser Ala Glu Ala 
                485                 490                 495


Ala Pro Pro Pro Gly Gln Pro Pro Gln Val Val Ala Asn Gly Pro Gly 
            500                 505                 510


Ser Gly Pro Pro Pro Pro Ala Gly Gly Ala Gly Ser Arg Asp Ala Leu 
        515                 520                 525


Phe Glu Ser Pro Pro Gly Gly Ser Gly Gly Asp Cys Ser Ala Gly Ser 
    530                 535                 540


Thr Pro Pro Ala Asp Ser Val Ala Ala Ala Gly Ala Gly Ala Ala Ala 
545                 550                 555                 560


Ala Gly Ser Gly Pro Ala Gly Ser Arg Val Pro Ala Pro His His Pro 
                565                 570                 575


His Leu Leu Glu Gly Arg Lys Ala Gly Gly Gly Ser Tyr His His Ser 
            580                 585                 590


Ser Ala Phe Arg Pro Val Gly Gly Lys Asp Asp Ala Glu Ser Leu Ala 
        595                 600                 605


Lys Leu His Gly Ala Ser Ala Gly Ala Pro His Ser Ala Gln Thr Cys 
    610                 615                 620


Cys Tyr Pro Ser Glu Asp Ser Ser Glu Asp Glu Asp Asp Glu Glu Glu 
625                 630                 635                 640


Glu Gln Glu Val Asp Val Glu Gly His Lys Pro Pro Glu Val Gly Gly 
                645                 650                 655


Gly Arg Phe Leu Gln Gly Arg Gly Pro Ser Glu Lys Gly Ser Ser Arg 
            660                 665                 670


Asp Arg Ala Pro Ala Val Ala Gly Ala Phe Pro Leu Gly Leu Asn Ser 
        675                 680                 685


Ser Arg Leu Leu Gln Glu Asp Gly Lys Leu Gly Asp Pro Gly Ser Asp 
    690                 695                 700


Leu Pro Pro Pro Pro Pro Pro Pro Leu Ala Pro Gln Lys Ala Ser Gly 
705                 710                 715                 720


Gly Gly Ser Ser Ser Pro Gly Ser Pro Val His His Pro Ser Leu Glu 
                725                 730                 735


Glu Gln Pro Ser Tyr Lys Asp Ser Gln Lys Thr Lys Glu Asn Asn Gln 
            740                 745                 750


Val Ile Val Ser Thr Lys Asp Asp Asn Ser Phe Ser Asp Lys Asn Lys 
        755                 760                 765


Glu His Ser Phe Phe Ile Thr Asp Ser Asp Ala Ser Gly Gly Asp Phe 
    770                 775                 780


Trp Arg Glu Arg Ser Gly Glu His Thr Gln Glu Thr Asn Ser Pro His 
785                 790                 795                 800


Ser Leu Lys Lys Asp Val Glu Asn Met Gly Lys Glu Glu Leu Gln Lys 
                805                 810                 815


Val Leu Phe Glu Gln Ile Asp Leu Arg Arg Arg Leu Glu Gln Glu Phe 
            820                 825                 830


Gln Val Leu Lys Gly Asn Thr Ser Phe Pro Val Phe Ile Tyr His Pro 
        835                 840                 845


Gly Gln Arg His Leu Gly Ser Leu Glu Ala Gln Arg Lys Val Phe Phe 
    850                 855                 860


Phe Thr Lys Gly Ala Met Leu Ala Met Cys Ser Ser Val Trp Asn His 
865                 870                 875                 880


Thr Asp Leu Pro Gly Gly Leu Arg Ala Thr Ala Gln Asp Gln Val Leu 
                885                 890                 895


Glu Pro Gly Gln Phe Val Glu Gly Trp Phe Pro Cys Cys Pro Val Pro 
            900                 905                 910


Leu Asp Pro Pro Leu Glu His Pro Asp Leu Asn Ala Val Leu His Val 
        915                 920                 925


Ser Ala Gln Ala Ala Leu Pro Ser Asn Val Pro Arg Met Asn Asp Ser 
    930                 935                 940


Ser Ser Leu Asn Leu Cys Met Ala Pro His Thr Ser Leu Tyr Tyr Ser 
945                 950                 955                 960


Asp Phe Asp Ile Lys Ile Arg Asp Pro Leu Cys Ser Lys Phe Asp Gln 
                965                 970                 975


Glu Arg Lys Ala Trp Arg Pro Ser Gln Gln Lys Leu Lys Asp Phe Leu 
            980                 985                 990


Leu Phe Met Val Leu Thr Pro Gln Leu Leu Pro Gln Gly Asn Gln Ser 
        995                 1000                1005


Val Ser Ser His Pro Gln Gly Val Ser Ser Leu Ser Leu Leu Arg Phe 
    1010                1015                1020


Gln Lys Ala Cys Leu Lys Ser Asp Phe Gln Arg Val Thr Ala Gly Glu 
1025                1030                1035                1040


Arg Gly His Val His Glu Ser Gln Pro Lys Thr Thr Cys Leu Pro Val 
                1045                1050                1055


Val Leu Leu Ile Glu Pro Ile Val Gly Leu Pro Thr Tyr Cys Asp Val 
            1060                1065                1070


Lys Ser Lys Ser Thr Arg Ser Tyr Tyr Ala Pro Asn Ser Ala Phe Gln 
        1075                1080                1085


Met Arg Glu Leu Asn Ser Glu His Phe Ala Ala Lys Ile Ser Lys Tyr 
    1090                1095                1100


Thr Gln Val Lys Ile Arg Lys Gly Asp Glu Pro Glu Leu Gly Trp Leu 
1105                1110                1115                1120


Ser Arg Thr Gln Arg His Val Glu Ala Ala Arg Ala Trp Gly Phe Pro 
                1125                1130                1135


Pro Leu Lys Pro His Pro Glu Leu Tyr Val Gly Arg Phe Gln Thr Trp 
            1140                1145                1150


Leu Gly Arg Leu Gly His Arg Ala Pro Ser Pro 
        1155                1160


<210>  9046
<211>  891
<212>  DNA
<213>  Homo sapiens

<400>  9046
atggcttcca gtccgctgcc agggcccaac gacatcctgc tggcgtcgcc gtcgagcgcc     60

ttccagcccg acacgctgag ccagccgcgg ccagggcacg ccaacctcaa acccaaccag    120

gtgggccagg tgatcctcta cggcattccc atcgtgtcgt tggtgatcga cgggcaagag    180

cgcctgtgcc tggcgcagat ctccaacact ctgctcaaga acttcagcta caacgagatc    240

cacaaccgtc gcgtggcact gggcatcacg tgtgtgcagt gcacgccggt gcaactggag    300

atcctgcggc gtgccggggc catgcccatc tcatcgcgcc gctgcggcat gatcaccaaa    360

cgcgaggccg agcgtctgtg caagtcgttc ctgggcgaaa acaggccgcc caagctgcca    420

gacaatttcg ccttcgacgt gtcacacgag tgcgcctggg gctgccgcgg cagcttcatt    480

cccgcgcgct acaacagctc gcgcgccaag tgcatcaaat gcagctactg caacatgtac    540

ttctcgccca acaagttcat tttccactcc caccgcacgc ccgacgccaa gtacactcag    600

ccagacgcag ccaacttcaa ctcgtggcgc cgtcatctca agctcaccga caagagtccc    660

caggacgagc tggtcttcgc ctgggaggac gtcaaggcca tgttcaacgg cggcagccgc    720

aagcgcgcac tgccccagcc gggcgcgcac cccgcctgcc acccgctcag ctctataaga    780

acaaggagca tagctttttc atcacagact ctgatgcttc tggaggagat ttttggagag    840

aaagatcagg aggattatat gcgaataaat gaggacaaca tttggttatg a             891


<210>  9047
<211>  296
<212>  PRT
<213>  Homo sapiens

<400>  9047

Met Ala Ser Ser Pro Leu Pro Gly Pro Asn Asp Ile Leu Leu Ala Ser 
1               5                   10                  15


Pro Ser Ser Ala Phe Gln Pro Asp Thr Leu Ser Gln Pro Arg Pro Gly 
            20                  25                  30


His Ala Asn Leu Lys Pro Asn Gln Val Gly Gln Val Ile Leu Tyr Gly 
        35                  40                  45


Ile Pro Ile Val Ser Leu Val Ile Asp Gly Gln Glu Arg Leu Cys Leu 
    50                  55                  60


Ala Gln Ile Ser Asn Thr Leu Leu Lys Asn Phe Ser Tyr Asn Glu Ile 
65                  70                  75                  80


His Asn Arg Arg Val Ala Leu Gly Ile Thr Cys Val Gln Cys Thr Pro 
                85                  90                  95


Val Gln Leu Glu Ile Leu Arg Arg Ala Gly Ala Met Pro Ile Ser Ser 
            100                 105                 110


Arg Arg Cys Gly Met Ile Thr Lys Arg Glu Ala Glu Arg Leu Cys Lys 
        115                 120                 125


Ser Phe Leu Gly Glu Asn Arg Pro Pro Lys Leu Pro Asp Asn Phe Ala 
    130                 135                 140


Phe Asp Val Ser His Glu Cys Ala Trp Gly Cys Arg Gly Ser Phe Ile 
145                 150                 155                 160


Pro Ala Arg Tyr Asn Ser Ser Arg Ala Lys Cys Ile Lys Cys Ser Tyr 
                165                 170                 175


Cys Asn Met Tyr Phe Ser Pro Asn Lys Phe Ile Phe His Ser His Arg 
            180                 185                 190


Thr Pro Asp Ala Lys Tyr Thr Gln Pro Asp Ala Ala Asn Phe Asn Ser 
        195                 200                 205


Trp Arg Arg His Leu Lys Leu Thr Asp Lys Ser Pro Gln Asp Glu Leu 
    210                 215                 220


Val Phe Ala Trp Glu Asp Val Lys Ala Met Phe Asn Gly Gly Ser Arg 
225                 230                 235                 240


Lys Arg Ala Leu Pro Gln Pro Gly Ala His Pro Ala Cys His Pro Leu 
                245                 250                 255


Ser Ser Ile Arg Thr Arg Ser Ile Ala Phe Ser Ser Gln Thr Leu Met 
            260                 265                 270


Leu Leu Glu Glu Ile Phe Gly Glu Lys Asp Gln Glu Asp Tyr Met Arg 
        275                 280                 285


Ile Asn Glu Asp Asn Ile Trp Leu 
    290                 295


<210>  9048
<211>  2432
<212>  DNA
<213>  Homo sapiens

<400>  9048
atggcttcca gtccgctgcc agggcccaac gacatcctgc tggcgtcgcc gtcgagcgcc     60

ttccagcccg acacgctgag ccagccgcgg ccagggcacg ccaacctcaa acccaaccag    120

gtgggccagg tgatcctcta cggcattccc atcgtgtcgt tggtgatcga cgggcaagag    180

cgcctgtgcc tggcgcagat ctccaacact ctgctcaaga acttcagcta caacgagatc    240

cacaaccgtc gcgtggcact gggcatcacg tgtgtgcagt gcacgccggt gcaactggag    300

atcctgcggc gtgccggggc catgcccatc tcatcgcgcc gctgcggcat gatcaccaaa    360

cgcgaggccg agcgtctgtg caagtcgttc ctgggcgaaa acaggccgcc caagctgcca    420

gacaatttcg ccttcgacgt gtcacacgag tgcgcctggg gctgccgcgg cagcttcatt    480

cccgcgcgct acaacagctc gcgcgccaag tgcatcaaat gcagctactg caacatgtac    540

ttctcgccca acaagttcat tttccactcc caccgcacgc ccgacgccaa gtacactcag    600

ccagacgcag ccaacttcaa ctcgtggcgc cgtcatctca agctcaccga caagagtccc    660

caggacgagc tggtcttcgc ctgggaggac gtcaaggcca tgttcaacgg cggcagccgc    720

aagcgcgcac tgccccagcc gggcgcgcac cccgcctgcc acccgctcag ctctgtgaag    780

gcggccgccg tggccgccgc ggccgcggtg gccggaggcg ggggtctgct gggcccccac    840

ctgctgggtg cgcccccgcc gccgccgccg ccaccgccgc ccttggcaga gctggctggt    900

gccccgcacg cccatcacaa gcggccgcgc ttcgacgacg acgacgactc cttgcaggag    960

gccgccgtag tggccgccgc cagcctctcg gccgcagccg ccagcctctc tgtggctgct   1020

gcttcgggcg gggccaaagg cccgcgcagc tacccagtca tcccggtgcc cagcaagggc   1080

tcgttcgggg gcgtcctgca gaagttcccg ggctgcggcg ggctcttccc gcacccctac   1140

accttccctg ccgcggccgc cgccttcagc ttgtgccata agaaagagga tgcgggtgcc   1200

gccgctgagg ccctgggggg cgcgggcgca ggcggcgcgg gcgcggcgcc caaggccggc   1260

ttgtccggcc tcttctggcc cgcgggccgc aaggacgcct tctatccgcc cttctgcatg   1320

ttctggccgc cgcggacccc tggcgggctc ccggtgccca cctacctgca gcccccgcct   1380

cagccgccct cggcgctagg ctgcgcgcta ggcgaaagcc cggccctgct gcgccaggcc   1440

ttcctggacc tggctgagcc aggcggtgct gctgggagcg ccgaggccgc gcccccgccg   1500

gggcagcccc cgcaggtagt ggccaacggc ccgggctccg gcccacctcc tcctgccggg   1560

ggcgccggct ctcgcgacgc gctcttcgag tcgcccccgg gcggcagcgg cggggactgc   1620

agcgcgggct ccacgccgcc cgcggactct gtggcagctg ccggggcagg ggccgcggcc   1680

gccgggtctg gccccgcggg ctcccgggtt ccggcgcccc accatccgca ccttctggag   1740

gggcgcaaag cgggcggtgg cagctaccac cattccagcg ccttccggcc agtgggcggc   1800

aaggacgacg cggagagcct ggccaagctg cacggggcgt cggcgggcgc gccccactcg   1860

gcccagacct gctgctaccc cagcgaggac agctccgtcg ggggcggccg gttcctccag   1920

ggccgagggc cgtcggagaa ggggagcagc cgggaccgcg cgccggccgt cgcgggcgcg   1980

ttcccgctcg gcctgaactc ctccaggctg ctgcaggaag acgggaaact cggggacccc   2040

ggctcggacc tgcccccgcc cccgccgccg cccctggccc cccagaaggc gagtggcggc   2100

ggcagcagca gcccgggcag cccagttcac catccatcac tggaggagca gccctcctac   2160

aaagatagtc agaaaactaa ggaaaataac caagtaattg tatctacaaa ggatgacaac   2220

agcttttcag ataagaacaa ggagcatagc tttttcatca cagactctga tgcttctgga   2280

ggagattttt ggagagaaag atcaggtagg ctgggaattc agaaatagat tacctaagaa   2340

ggcagtatga gtactataat cgtagtctac acaaaaaacc atctgataag atttatataa   2400

ccctgtgtcc ctttagccaa tccaatgttt aa                                 2432


<210>  9049
<211>  775
<212>  PRT
<213>  Homo sapiens

<400>  9049

Met Ala Ser Ser Pro Leu Pro Gly Pro Asn Asp Ile Leu Leu Ala Ser 
1               5                   10                  15


Pro Ser Ser Ala Phe Gln Pro Asp Thr Leu Ser Gln Pro Arg Pro Gly 
            20                  25                  30


His Ala Asn Leu Lys Pro Asn Gln Val Gly Gln Val Ile Leu Tyr Gly 
        35                  40                  45


Ile Pro Ile Val Ser Leu Val Ile Asp Gly Gln Glu Arg Leu Cys Leu 
    50                  55                  60


Ala Gln Ile Ser Asn Thr Leu Leu Lys Asn Phe Ser Tyr Asn Glu Ile 
65                  70                  75                  80


His Asn Arg Arg Val Ala Leu Gly Ile Thr Cys Val Gln Cys Thr Pro 
                85                  90                  95


Val Gln Leu Glu Ile Leu Arg Arg Ala Gly Ala Met Pro Ile Ser Ser 
            100                 105                 110


Arg Arg Cys Gly Met Ile Thr Lys Arg Glu Ala Glu Arg Leu Cys Lys 
        115                 120                 125


Ser Phe Leu Gly Glu Asn Arg Pro Pro Lys Leu Pro Asp Asn Phe Ala 
    130                 135                 140


Phe Asp Val Ser His Glu Cys Ala Trp Gly Cys Arg Gly Ser Phe Ile 
145                 150                 155                 160


Pro Ala Arg Tyr Asn Ser Ser Arg Ala Lys Cys Ile Lys Cys Ser Tyr 
                165                 170                 175


Cys Asn Met Tyr Phe Ser Pro Asn Lys Phe Ile Phe His Ser His Arg 
            180                 185                 190


Thr Pro Asp Ala Lys Tyr Thr Gln Pro Asp Ala Ala Asn Phe Asn Ser 
        195                 200                 205


Trp Arg Arg His Leu Lys Leu Thr Asp Lys Ser Pro Gln Asp Glu Leu 
    210                 215                 220


Val Phe Ala Trp Glu Asp Val Lys Ala Met Phe Asn Gly Gly Ser Arg 
225                 230                 235                 240


Lys Arg Ala Leu Pro Gln Pro Gly Ala His Pro Ala Cys His Pro Leu 
                245                 250                 255


Ser Ser Val Lys Ala Ala Ala Val Ala Ala Ala Ala Ala Val Ala Gly 
            260                 265                 270


Gly Gly Gly Leu Leu Gly Pro His Leu Leu Gly Ala Pro Pro Pro Pro 
        275                 280                 285


Pro Pro Pro Pro Pro Pro Leu Ala Glu Leu Ala Gly Ala Pro His Ala 
    290                 295                 300


His His Lys Arg Pro Arg Phe Asp Asp Asp Asp Asp Ser Leu Gln Glu 
305                 310                 315                 320


Ala Ala Val Val Ala Ala Ala Ser Leu Ser Ala Ala Ala Ala Ser Leu 
                325                 330                 335


Ser Val Ala Ala Ala Ser Gly Gly Ala Lys Gly Pro Arg Ser Tyr Pro 
            340                 345                 350


Val Ile Pro Val Pro Ser Lys Gly Ser Phe Gly Gly Val Leu Gln Lys 
        355                 360                 365


Phe Pro Gly Cys Gly Gly Leu Phe Pro His Pro Tyr Thr Phe Pro Ala 
    370                 375                 380


Ala Ala Ala Ala Phe Ser Leu Cys His Lys Lys Glu Asp Ala Gly Ala 
385                 390                 395                 400


Ala Ala Glu Ala Leu Gly Gly Ala Gly Ala Gly Gly Ala Gly Ala Ala 
                405                 410                 415


Pro Lys Ala Gly Leu Ser Gly Leu Phe Trp Pro Ala Gly Arg Lys Asp 
            420                 425                 430


Ala Phe Tyr Pro Pro Phe Cys Met Phe Trp Pro Pro Arg Thr Pro Gly 
        435                 440                 445


Gly Leu Pro Val Pro Thr Tyr Leu Gln Pro Pro Pro Gln Pro Pro Ser 
    450                 455                 460


Ala Leu Gly Cys Ala Leu Gly Glu Ser Pro Ala Leu Leu Arg Gln Ala 
465                 470                 475                 480


Phe Leu Asp Leu Ala Glu Pro Gly Gly Ala Ala Gly Ser Ala Glu Ala 
                485                 490                 495


Ala Pro Pro Pro Gly Gln Pro Pro Gln Val Val Ala Asn Gly Pro Gly 
            500                 505                 510


Ser Gly Pro Pro Pro Pro Ala Gly Gly Ala Gly Ser Arg Asp Ala Leu 
        515                 520                 525


Phe Glu Ser Pro Pro Gly Gly Ser Gly Gly Asp Cys Ser Ala Gly Ser 
    530                 535                 540


Thr Pro Pro Ala Asp Ser Val Ala Ala Ala Gly Ala Gly Ala Ala Ala 
545                 550                 555                 560


Ala Gly Ser Gly Pro Ala Gly Ser Arg Val Pro Ala Pro His His Pro 
                565                 570                 575


His Leu Leu Glu Gly Arg Lys Ala Gly Gly Gly Ser Tyr His His Ser 
            580                 585                 590


Ser Ala Phe Arg Pro Val Gly Gly Lys Asp Asp Ala Glu Ser Leu Ala 
        595                 600                 605


Lys Leu His Gly Ala Ser Ala Gly Ala Pro His Ser Ala Gln Thr Cys 
    610                 615                 620


Cys Tyr Pro Ser Glu Asp Ser Ser Val Gly Gly Gly Arg Phe Leu Gln 
625                 630                 635                 640


Gly Arg Gly Pro Ser Glu Lys Gly Ser Ser Arg Asp Arg Ala Pro Ala 
                645                 650                 655


Val Ala Gly Ala Phe Pro Leu Gly Leu Asn Ser Ser Arg Leu Leu Gln 
            660                 665                 670


Glu Asp Gly Lys Leu Gly Asp Pro Gly Ser Asp Leu Pro Pro Pro Pro 
        675                 680                 685


Pro Pro Pro Leu Ala Pro Gln Lys Ala Ser Gly Gly Gly Ser Ser Ser 
    690                 695                 700


Pro Gly Ser Pro Val His His Pro Ser Leu Glu Glu Gln Pro Ser Tyr 
705                 710                 715                 720


Lys Asp Ser Gln Lys Thr Lys Glu Asn Asn Gln Val Ile Val Ser Thr 
                725                 730                 735


Lys Asp Asp Asn Ser Phe Ser Asp Lys Asn Lys Glu His Ser Phe Phe 
            740                 745                 750


Ile Thr Asp Ser Asp Ala Ser Gly Gly Asp Phe Trp Arg Glu Arg Ser 
        755                 760                 765


Gly Arg Leu Gly Ile Gln Lys 
    770                 775


<210>  9050
<211>  742
<212>  DNA
<213>  Homo sapiens

<400>  9050
tgtgttgctc cctgttgctt tctacggggt ctgcgctggc ctcctcctcg ggcgactggg     60

ccctgaggca acagcgcctt ctcgagcccc gaggattgac cgccccgagc ctgcttggag    120

cagggcctct ctccagcgcg gtgtgatgaa acaccagctg ctgtgaagat atacccttag    180

aaacgaaccg tctgttaata tgcttatgaa aacaggggct cagagaggat gtacttttct    240

caagaccaca cagctggaaa aaaaccattc ttccaggaga ggctcctcca agcaaacttc    300

cccttacatc tcttaccaga actgggtcac atgctcccat ctaaaacaac cactggccat    360

tagaaatggt gttaccatgc ctgtcttgga ccaatcacat ttgatcctct gaggatagag    420

acatgttgcc acctgaacaa ctgtggggtg ctgtactcct ggcaagcagg gagaatggct    480

gtggctaggc aactgacagc atctaccaca aatatgttac tcagaagaag aatcgaggat    540

ggccataatt tttatttaaa gatttctatt ttacagaggc atatctgatt aagggacatt    600

taaacttccc tgttaaactt atcaagacaa aaagacaagg catcttgcca catttcttaa    660

atattctctg cagtctctct tgaccttttc ccagctgtgc tgtaaacata aagataataa    720

catatctgaa taacatttta tg                                             742


<210>  9051
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  9051

Met Leu Met Lys Thr Gly Ala Gln Arg Gly Cys Thr Phe Leu Lys Thr 
1               5                   10                  15


Thr Gln Leu Glu Lys Asn His Ser Ser Arg Arg Gly Ser Ser Lys Gln 
            20                  25                  30


Thr Ser Pro Tyr Ile Ser Tyr Gln Asn Trp Val Thr Cys Ser His Leu 
        35                  40                  45


Lys Gln Pro Leu Ala Ile Arg Asn Gly Val Thr Met Pro Val Leu Asp 
    50                  55                  60


Gln Ser His Leu Ile Leu 
65                  70


<210>  9052
<211>  821
<212>  DNA
<213>  Homo sapiens

<400>  9052
gtggtggttt cccctgttct cgctctttcc tgctgccttg tgaggaaggt acttgcttct     60

cctttgcctt gtgccgtgat tgtaagtttc ctgaggcctc cccaaccatg cagaactgag    120

cagacaattg agaggcctgg ctcatggatg ggtttgaacc acctcaggac tgaagatgag    180

cggctcagtt tcactaacaa caagaacagt gacaaattcc ctgcccggcc caagctctgt    240

ggtccttatg caggtagagt cctcatgctg aatgtttgca agctgactct tcaataagac    300

cgtgagctcc ttgagaaagg aattgggtct ctgtgcagtg tatcacatct acctcaatgc    360

tctgcttaga ggaagtgttt gaaaattttt tgtgtgataa ataataatac taatccagtt    420

aagatatact gccctcggta tgaaaaactc tatcccaagg tggagcagct ttgaaaatgt    480

ggttggacga aaatgaaatt tcagatgtgt gtgtctcagc attgattttt ctatttgtaa    540

taacacaccc tggcatatct cctttgatat caagaggata aaatgtccct aacagcatgc    600

tcttcattct gggatgccag tggcacccct gtcccagatg tgacaaccaa aaatgatgtc    660

agacattgct gaattgtccc ctggaggagg agaaaaatca acccctttga gaactgctgg    720

gcagctctaa aggtcatccc taagttcagg gtgaggagat gacctaccct tctgccccgc    780

aacgccatcc tacatctgaa attcttctta agggcatggt g                        821


<210>  9053
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  9053

Met Gly Leu Asn His Leu Arg Thr Glu Asp Glu Arg Leu Ser Phe Thr 
1               5                   10                  15


Asn Asn Lys Asn Ser Asp Lys Phe Pro Ala Arg Pro Lys Leu Cys Gly 
            20                  25                  30


Pro Tyr Ala Gly Arg Val Leu Met Leu Asn Val Cys Lys Leu Thr Leu 
        35                  40                  45


Gln 



<210>  9054
<211>  5756
<212>  DNA
<213>  Homo sapiens

<400>  9054
ctttccctgt gtcagatcag ggatcatttt ttttccttcc tctactccct cccccctacc     60

cgcccctccc tccctgtttc ccttccctcc ctccctcccc tctctgctgg gtctgtgcgc    120

tggggcgccc gatcccctcc gcagctggga cgctccgaac tcgaggcagg agtcggctct    180

ccggagcctc gtccctccct tccccttccc tgcccccttc ccccaccccc gactcgggct    240

tggcgcggcg gccagaggaa ccccgagtcc cggcccaggc ccctgagctg gagggatgga    300

aaactcctct gcagcatcag cctcctcgga ggcagggagc agccgctccc aggagatcga    360

ggagctggag cgcttcatcg acagctacgt gctggagtac caggtgcagg ggctgctggc    420

tgacaagacg gagggtgatg gcgagagcga gaggacccag tcccacatct cccagtggac    480

agcggactgc agcgaaccgc tggacagcag ctgttccttc tcccgagggc gagccccccc    540

acagcagaat ggcagcaaag acaactctct ggacatgctg ggcacggaca tctgggcggc    600

caacaccttc gattccttca gtggtgccac ctgggacctg cagccggaaa agctggactt    660

cacccagttc caccgcaaag tccgacacac gcccaagcag cccctgccac acatcgaccg    720

cgaagggtgt ggcaaaggga agctggaaga tggggatggc atcaacctga atgacatcga    780

gaaggtcctt ccagcctggc agggctacca cccgatgccc catgaagtgg agatcgcaca    840

caccaagaag ctgttccgca ggaggagaaa tgatcgaagg cggcagcaga gacctccggg    900

gggcaacaag ccccaacagc atggtgacca ccagccaggc agtgccaaac acaacaggga    960

ccaccagaaa tcctaccagg ggggctcagc accccacccc tcagggaggc ccactcacca   1020

tggctacagc cagaaccggc gctggcacca tggcaacatg aagcacccac caggcgacaa   1080

gggggaggca ggcgcacacc gcaatgccaa agagaccatg accatcgaga acccaaaact   1140

ggaggacact gcaggggaca ccgggcacag cagccttgag gccccccgca gccctgacac   1200

cctggccccg gtggcttctg agcggctgcc cccacagcag tcaggggggc cagaggttga   1260

gacaaaacgt aaagacagta ttcttcccga gcgcatcggg gagcggccca aaattaccct   1320

gctccagtct tccaaagaca gactgcggcg aaggctaaag gaaaaggtac cggatgaagt   1380

ggccgtggag acgaccactc cccagcagaa caagatggac aagctgatcg agatcctgaa   1440

cagcatgcgg aacaacagca gcgacgtgga caccaagctc accaccttca tggaggaggc   1500

ccagaactcc accaactccg aggagatgct gggcgagatc gtgcgcacaa tctaccagaa   1560

ggctgtgtcc gaccgcagct tcgccttcac cgctgccaag ctctgcgaca agatggcgct   1620

ctttatggtg gaggggacca agttccggag cctgctcctc aacatgctgc agaaggactt   1680

cacggtgcgc gaggagctgc agcagcagga cgtggagcgc tggctgggct tcatcacctt   1740

cctgtgcgag gtcttcggca ccatgcgcag cagcacaggc gagcccttcc gtgtgctcgt   1800

gtgccccatc tacacctgcc tcagggagct cttgcaatct caggatgtga aggaagatgc   1860

tgtcctttgc tgctctatgg agctgcagag tacaggccgg ctgctggagg aacagctgcc   1920

tgagatgatg acagagctcc tggccagcgc acgggacaag atgctgtgcc cctcggagtc   1980

catgctgacc cggtcgctgc tcctagaggt catcgagctc cacgctaaca gctggaaccc   2040

tctgacgccc cccatcacgc agtactacaa cagaaccatc cagaaactga cagcctgaca   2100

gccagggggc ctggcaggcg gcccacgggc agctggggcc ctggtgcaca gggccagatg   2160

gacaggcggg aggacagggg tggccctggc gggagaaaga aatggggagg agggcaggca   2220

gagtcggtgg ccagtctgga gccagacggg gaagggagca aatccctgag aggagtgccc   2280

ccgcacaagc cccccagccc gagcatgcaa gctcacacca ataagggaag catgtttctt   2340

tttcctggtg gccctggccc tccccttcct cactcccgcc tctcccctcc ccatcagacc   2400

catcccccac ggagctttgt gtgagggatc tcatcgctgt gactcctcgg agaccttggc   2460

agcctcgcac gccggggcac cgcttgggtc agaaaggacc tcggaaggct gaaaaagtgg   2520

gtcggagacg ggctcgcatt gttcccgcat gctgtcagcc gcagtcgcca actggcagca   2580

ggcgacgtgt agcagatgtc cgggaggaca aaggcaggca cggtccccac cagccgcccg   2640

taattgacgg cctttgtcag ccatggcaga gctgacgctc cacctcccac ctccaagtcc   2700

tcctcactgc agcccccaca gcctcaggcc tagggggtca ggcgcagcgg gggagatgga   2760

gtttgcagtt ccacttgcac tcttttgttt attgtgtttt atttttcaaa agtcggttgc   2820

tttgaagtct ctttggccaa tgaaaatgcc cgtgatgtga tcacacagtc agcactgttg   2880

aggacccccg gattagtggg agatcaaacc cagctcccct ctagaagaag gattcgagcc   2940

acagacagct tgccagtagc caattagggt aattggaaac ttctgccccg gcggggggtc   3000

cccgctggaa tcctgtgttc ctcgccactg gcttccagcg cctctgtttt ctcaaagggc   3060

tgatactgtc accactggga ccaagttaaa cctggtcctg gccccagggg ccttgtggca   3120

aacagggcac agaacgagac tggcaaatta aaaccaaaat tctagatggt gtcttgcgct   3180

ccacacgcag gtcttactgg ggaaaaggat gggagtgggg gctccccagg actcgatttt   3240

agctaatgcg ctgtgtcact gccccagctc ggacgtagaa gcccagccct ccgtgagctc   3300

ttgggaaagg ggtgaattca ctgggtcatg gaagggacag tcaggtgacc agcggggtcg   3360

ccagatgaag cttcccagcc gggaaacaag acggggtttc ttggcaggcc ctggtcctgg   3420

ggagcaggcc ctgttgttgg ctggagagga aggtgtgggg tggaacaggt gtccacatag   3480

ctccatctct gggggctgga gcacacactt tgatgagccc ccccggaaat gatgtcagag   3540

cctagccgct tccttatttg ctcttttatt gaggccgggc aggccctggg tcactttgga   3600

ggcccctctt ggtccacact ggactggccg ggaggtgatg ggcggggaag gttctcgtga   3660

ttgattgatt ctgagtctga gagtggcgag tggggagagg cttccccagt tctctccagc   3720

tttccctgca gctgcaacct gccctctggt cccaggtgtg gagcctttgc ctgtctctaa   3780

aaagagcctg ttggcgacaa ggtgtagggg gcacaagttt acctgaaaca ggtcagtggt   3840

ctctcccaag aagcgcacgc cacctctggt ccctggccct gaaccctgcc ttcttcctcc   3900

ctccacggtt tcttcccaga ctttctcaag ctcctcctca ctgcccttcc tccccagccc   3960

agcctgggaa cacagatgcc ccgcgggtag gaggcctcga gggaggagcc gggctgatgc   4020

ggggctgctc agggcaggcc ccagggcgag cttgccatcg tggccaggca gcctccacct   4080

gtgcttcagt ggcccctgcc cccctgaagc atgtggggtt tgtccgctag gaggaggcaa   4140

ggcccccgaa gagaggagag acctgggagt gggagctcag gtcagggagg aggcagggga   4200

gtggggtctc ccagacccaa cggtgagctc agagcaagct tcacgcagga cgctccgaaa   4260

cactgtgtgg agggggctgt gttgtgggca ccttggggcc tgattctcct tcctccgaac   4320

gggctccttg atggcctggc cacaggggca gctccccatt ggctgttagg accagagtgt   4380

gaagaagaag tgaaatataa atatgtatac atatataaat atatttttaa ttacatgtcg   4440

tgtcacggtg gctccagaca tactgtttgc ctagtttatt ccactgcttg aaagcgcttc   4500

ctagccaatc tgaacaacaa cactttaagc tgtttttcta aatgcaggtt gctgctcctt   4560

tttcagatat ggaaggaaaa cgttaagact attttttttt taaagaaaca acagtcaagc   4620

ctaaaatttg agaccccgag gcagcttccc gagggagact gctcagacag gaactgcagg   4680

acagaagtgg atgccccaca gaccctggcc ccctccccaa gtccatcccc tctctgtggc   4740

atgaggaagg ccgcgtccga gttgacctct gaatgtatgt gatgagaggc agagctggat   4800

attgcatttc taaggcttgc attgctttcc cctcgcccgc ggttcttggc gcatggaaga   4860

ggcggtccag ccatctgatg ttgatcctgt ctcagtctcc ccactgcctg tcaggatgag   4920

ttagtcattg tttttctccg aggcggcctg cttgccacag ccctgctccc caaggcctgg   4980

tggctttgcc gaagctctgg gaccgcagcc ccagcgaggc ccccaacctc acccagacga   5040

ggccaggagc cccgccaccc tccacgggat gtgcaccctc agaccccatt ctctctgttc   5100

gtccttcctt gaccagtctg taaaccttca ctgtttgggg atcgtcctgt ccatccatgt   5160

aaatgtaaat gttggccgag tcggtattta ttctgattga tttttatttt attctattat   5220

tttctccgag ggatgagggt ggggggtgtg ggaagggtac cacagatcag gccggggcag   5280

ctgtaggggc gggggcccag acagccaggc cgccaccaga gcagccccat ggggtgcccc   5340

agacgcgggc ctccaagaag ccaagtccca gtctgttttc tggcatcaga caccggcccg   5400

tgttccttgt cagacagaca gactctcagg cctgcctggg gagtcgtgtc cctcagctgc   5460

agggcactgt gttgggaaac cattggctgg gcctttgagg acacagatca gaagaaagaa   5520

agacaacttt cctctgcgcg gaacactcac acggaagggc tggccgcctc cctgagccgg   5580

ctgggagtgg acgacaggac ctacctcccc agagcaaggg cctggggctt cccgccaaag   5640

ctgccgcgga accccgctag tgcgaccacc ctccctccgt cggtatgtcc tgctttccag   5700

ctgaacccaa actacaagtg ggtttaaaaa aataaacacc accaccaaaa acaaaa       5756


<210>  9055
<211>  600
<212>  PRT
<213>  Homo sapiens

<400>  9055

Met Glu Asn Ser Ser Ala Ala Ser Ala Ser Ser Glu Ala Gly Ser Ser 
1               5                   10                  15


Arg Ser Gln Glu Ile Glu Glu Leu Glu Arg Phe Ile Asp Ser Tyr Val 
            20                  25                  30


Leu Glu Tyr Gln Val Gln Gly Leu Leu Ala Asp Lys Thr Glu Gly Asp 
        35                  40                  45


Gly Glu Ser Glu Arg Thr Gln Ser His Ile Ser Gln Trp Thr Ala Asp 
    50                  55                  60


Cys Ser Glu Pro Leu Asp Ser Ser Cys Ser Phe Ser Arg Gly Arg Ala 
65                  70                  75                  80


Pro Pro Gln Gln Asn Gly Ser Lys Asp Asn Ser Leu Asp Met Leu Gly 
                85                  90                  95


Thr Asp Ile Trp Ala Ala Asn Thr Phe Asp Ser Phe Ser Gly Ala Thr 
            100                 105                 110


Trp Asp Leu Gln Pro Glu Lys Leu Asp Phe Thr Gln Phe His Arg Lys 
        115                 120                 125


Val Arg His Thr Pro Lys Gln Pro Leu Pro His Ile Asp Arg Glu Gly 
    130                 135                 140


Cys Gly Lys Gly Lys Leu Glu Asp Gly Asp Gly Ile Asn Leu Asn Asp 
145                 150                 155                 160


Ile Glu Lys Val Leu Pro Ala Trp Gln Gly Tyr His Pro Met Pro His 
                165                 170                 175


Glu Val Glu Ile Ala His Thr Lys Lys Leu Phe Arg Arg Arg Arg Asn 
            180                 185                 190


Asp Arg Arg Arg Gln Gln Arg Pro Pro Gly Gly Asn Lys Pro Gln Gln 
        195                 200                 205


His Gly Asp His Gln Pro Gly Ser Ala Lys His Asn Arg Asp His Gln 
    210                 215                 220


Lys Ser Tyr Gln Gly Gly Ser Ala Pro His Pro Ser Gly Arg Pro Thr 
225                 230                 235                 240


His His Gly Tyr Ser Gln Asn Arg Arg Trp His His Gly Asn Met Lys 
                245                 250                 255


His Pro Pro Gly Asp Lys Gly Glu Ala Gly Ala His Arg Asn Ala Lys 
            260                 265                 270


Glu Thr Met Thr Ile Glu Asn Pro Lys Leu Glu Asp Thr Ala Gly Asp 
        275                 280                 285


Thr Gly His Ser Ser Leu Glu Ala Pro Arg Ser Pro Asp Thr Leu Ala 
    290                 295                 300


Pro Val Ala Ser Glu Arg Leu Pro Pro Gln Gln Ser Gly Gly Pro Glu 
305                 310                 315                 320


Val Glu Thr Lys Arg Lys Asp Ser Ile Leu Pro Glu Arg Ile Gly Glu 
                325                 330                 335


Arg Pro Lys Ile Thr Leu Leu Gln Ser Ser Lys Asp Arg Leu Arg Arg 
            340                 345                 350


Arg Leu Lys Glu Lys Val Pro Asp Glu Val Ala Val Glu Thr Thr Thr 
        355                 360                 365


Pro Gln Gln Asn Lys Met Asp Lys Leu Ile Glu Ile Leu Asn Ser Met 
    370                 375                 380


Arg Asn Asn Ser Ser Asp Val Asp Thr Lys Leu Thr Thr Phe Met Glu 
385                 390                 395                 400


Glu Ala Gln Asn Ser Thr Asn Ser Glu Glu Met Leu Gly Glu Ile Val 
                405                 410                 415


Arg Thr Ile Tyr Gln Lys Ala Val Ser Asp Arg Ser Phe Ala Phe Thr 
            420                 425                 430


Ala Ala Lys Leu Cys Asp Lys Met Ala Leu Phe Met Val Glu Gly Thr 
        435                 440                 445


Lys Phe Arg Ser Leu Leu Leu Asn Met Leu Gln Lys Asp Phe Thr Val 
    450                 455                 460


Arg Glu Glu Leu Gln Gln Gln Asp Val Glu Arg Trp Leu Gly Phe Ile 
465                 470                 475                 480


Thr Phe Leu Cys Glu Val Phe Gly Thr Met Arg Ser Ser Thr Gly Glu 
                485                 490                 495


Pro Phe Arg Val Leu Val Cys Pro Ile Tyr Thr Cys Leu Arg Glu Leu 
            500                 505                 510


Leu Gln Ser Gln Asp Val Lys Glu Asp Ala Val Leu Cys Cys Ser Met 
        515                 520                 525


Glu Leu Gln Ser Thr Gly Arg Leu Leu Glu Glu Gln Leu Pro Glu Met 
    530                 535                 540


Met Thr Glu Leu Leu Ala Ser Ala Arg Asp Lys Met Leu Cys Pro Ser 
545                 550                 555                 560


Glu Ser Met Leu Thr Arg Ser Leu Leu Leu Glu Val Ile Glu Leu His 
                565                 570                 575


Ala Asn Ser Trp Asn Pro Leu Thr Pro Pro Ile Thr Gln Tyr Tyr Asn 
            580                 585                 590


Arg Thr Ile Gln Lys Leu Thr Ala 
        595                 600


<210>  9056
<211>  4484
<212>  DNA
<213>  Homo sapiens

<400>  9056
ccttcctcta ctccctcccc cctacccgcc cctccctccc tgtttccctt ccctccctcc     60

ctcccctctc tgctgggtct gtgcgctggg gcgcccgatc ccctccgcag ctgggacgct    120

ccgaactcga ggcaggagtc ggctctccgg agcctcgtcc ctcccttccc cttccctgcc    180

cccttccccc acccccgact cgggcttggc gcggcggcca gaggaacccc gagcccgcat    240

ttgctgcatc gagcagttgg tttagtatca gccaaacttg cagctgttca gaccgcgctc    300

cgccgagtcc cggcccaggc ccctgagctg gagggatgga aaactcctct gcagcatcag    360

cctcctcgga ggcagggagc agccgctccc aggagatcga ggagctggag cgcttcatcg    420

acagctacgt gctggagtac caggtgcagg ggctgctggc tgacaagacg gagggtgatg    480

gcgagagcga gaggacccag tcccacatct cccagtggac agcggactgc agcgaaccgc    540

tggacagcag ctgttccttc tcccgagggc gagccccccc acagcagaat ggcagcaaag    600

acaactctct ggacatgctg ggcacggaca tctgggcggc caacaccttc gattccttca    660

gtggtgccac ctgggacctg cagccggaaa agctggactt cacccagttc caccgcaaag    720

tccgacacac gcccaagcag cccctgccac acatcgaccg cgaagggtgt ggcaaaggga    780

agctggaaga tggggatggc atcaacctga atgacatcga gaaggtcctt ccagcctggc    840

agggctacca cccgatgccc catgaagtgg agatcgcaca caccaagaag ctgttccgca    900

ggaggagaaa tgatcgaagg cggcagcaga gacctccggg gggcaacaag ccccaacagc    960

atggtgacca ccagccaggc agtgccaaac acaacaggga ccaccagaaa tcctaccagg   1020

ggggctcagc accccacccc tcagggaggc ccactcacca tggctacagc cagaaccggc   1080

gctggcacca tggcaacatg aagcacccac caggcgacaa gggggaggca ggcgcacacc   1140

gcaatgccaa agagaccatg accatcgaga acccaaaact ggaggacact gcaggggaca   1200

ccgggcacag cagccttgag gccccccgca gccctgacac cctggccccg gtggcttctg   1260

agcggctgcc cccacagcag tcaggggggc cagaggttga gacaaaacgt aaagacagta   1320

ttcttcccga gcgcatcggg gagcggccca aaattaccct gctccagtct tccaaagaca   1380

gactgcggcg aaggctaaag gaaaaggtac cggatgaagt ggccgtggag acgaccactc   1440

cccagcagaa caagatggac aagctgatcg agatcctgaa cagcatgcgg aacaacagca   1500

gcgacgtgga caccaagctc accaccttca tggaggaggc ccagaactcc accaactccg   1560

aggagatgct gggcgagatc gtgcgcacaa tctaccagaa ggctgtgtcc gaccgcagct   1620

tcgccttcac cgctgccaag ctctgcgaca agatggcgct ctttatggtg gaggggacca   1680

agttccggag cctgctcctc aacatgctgc agaaggactt cacggtgcgc gaggagctgc   1740

agcagcagga cgtggagcgc tggctgggct tcatcacctt cctgtgcgag gtcttcggca   1800

ccatgcgcag cagcacaggc gagcccttcc gtgtgctcgt gtgccccatc tacacctgcc   1860

tcagggagct cttgcaatct caggatgtga aggaagatgc tgtcctttgc tgctctatgg   1920

agctgcagag tacaggccgg ctgctggagg aacagctgcc tgagatgatg acagagctcc   1980

tggccagcgc acgggacaag atgctgtgcc cctcggagtc catgctgacc cggtcgctgc   2040

tcctagaggt catcgagctc cacgctaaca gctggaaccc tctgacgccc cccatcacgc   2100

agtactacaa cagaaccatc cagaaactga cagcctgaca gccagggggc ctggcaggcg   2160

gcccacgggc agctggggcc ctggtgcaca gggccagatg gacaggcggg aggacagggg   2220

tggccctggc gggagaaaga aatggggagg agggcaggca gagtcggtgg ccagtctgga   2280

gccagacggg gaagggagca aatccctgag aggagtgccc ccgcacaagc cccccagccc   2340

gagcatgcaa gctcacacca ataagggaag catgtttctt tttcctggtg gccctggccc   2400

tccccttcct cactcccgcc tctcccctcc ccatcagacc catcccccac ggagctttgt   2460

gtgagggatc tcatcgctgt gactcctcgg agaccttggc agcctcgcac gccggggcac   2520

cgcttgggtc agaaaggacc tcggaaggct gaaaaagtgg gtcggagacg ggctcgcatt   2580

gttcccgcat gctgtcagcc gcagtcgcca actggcagca ggcgacgtgt agcagatgtc   2640

cgggaggaca aaggcaggca cggtccccac cagccgcccg taattgacgg cctttgtcag   2700

ccatggcaga gctgacgctc cacctcccac ctccaagtcc tcctcactgc agcccccaca   2760

gcctcaggcc tagggggtca ggcgcagcgg gggagatgga gtttgcagtt ccacttgcac   2820

tcttttgttt attgtgtttt atttttcaaa agtcggttgc tttgaagtct ctttggccaa   2880

tgaaaatgcc cgtgatgtga tcacacagtc agcactgttg aggacccccg gattagtggg   2940

agatcaaacc cagctcccct ctagaagaag gattcgagcc acagacagct tgccagtagc   3000

caattagggt aattggaaac ttctgccccg gcggggggtc cccgctggaa tcctgtgttc   3060

ctcgccactg gcttccagcg cctctgtttt ctcaaagggc tgatactgtc accactggga   3120

ccaagttaaa cctggtcctg gccccagggg ccttgtggca aacagggcac agaacgagac   3180

tggcaaatta aaaccaaaat tctagatggt gtcttgcgct ccacacgcag gtcttactgg   3240

ggaaaaggat gggagtgggg gctccccagg actcgatttt agctaatgcg ctgtgtcact   3300

gccccagctc ggacgtagaa gcccagccct ccgtgagctc ttgggaaagg ggtgaattca   3360

ctgggtcatg gaagggacag tcaggtgacc agcggggtcg ccagatgaag cttcccagcc   3420

gggaaacaag acggggtttc ttggcaggcc ctggtcctgg ggagcaggcc ctgttgttgg   3480

ctggagagga aggtgtgggg tggaacaggt gtccacatag ctccatctct gggggctgga   3540

gcacacactt tgatgagccc ccccggaaat gatgtcagag cctagccgct tccttatttg   3600

ctcttttatt gaggccgggc aggccctggg tcactttgga ggcccctctt ggtccacact   3660

ggactggccg ggaggtgatg ggcggggaag gttctcgtga ttgattgatt ctgagtctga   3720

gagtggcgag tggggagagg cttccccagt tctctccagc tttccctgca gctgcaacct   3780

gccctctggt cccaggtgtg gagcctttgc ctgtctctaa aaagagcctg ttggcgacaa   3840

ggtgtagggg gcacaagttt acctgaaaca ggtcagtggt ctctcccaag aagcgcacgc   3900

cacctctggt ccctggccct gaaccctgcc ttcttcctcc ctccacggtt tcttcccaga   3960

ctttctcaag ctcctcctca ctgcccttcc tccccagccc agcctgggaa cacagatgcc   4020

ccgcgggtag gaggcctcga gggaggagcc gggctgatgc ggggctgctc agggcaggcc   4080

ccagggcgag cttgccatcg tggccaggca gcctccacct gtgcttcagt ggcccctgcc   4140

cccctgaagc atgtggggtt tgtccgctag gaggaggcaa ggcccccgaa gagaggagag   4200

acctgggagt gggagctcag gtcagggagg aggcagggga gtggggtctc ccagacccaa   4260

cggtgagctc agagcaagct tcacgcagga cgctccgaaa cactgtgtgg agggggctgt   4320

gttgtgggca ccttggggcc tgattctcct tcctccgaac gggctccttg atggcctggc   4380

cacaggggca gctccccatt ggctgttagg accagagtgt gaagaagaag tgaaatataa   4440

atatgtatac atatataaat atatttttaa ttacatgtcg tgtc                    4484


<210>  9057
<211>  600
<212>  PRT
<213>  Homo sapiens

<400>  9057

Met Glu Asn Ser Ser Ala Ala Ser Ala Ser Ser Glu Ala Gly Ser Ser 
1               5                   10                  15


Arg Ser Gln Glu Ile Glu Glu Leu Glu Arg Phe Ile Asp Ser Tyr Val 
            20                  25                  30


Leu Glu Tyr Gln Val Gln Gly Leu Leu Ala Asp Lys Thr Glu Gly Asp 
        35                  40                  45


Gly Glu Ser Glu Arg Thr Gln Ser His Ile Ser Gln Trp Thr Ala Asp 
    50                  55                  60


Cys Ser Glu Pro Leu Asp Ser Ser Cys Ser Phe Ser Arg Gly Arg Ala 
65                  70                  75                  80


Pro Pro Gln Gln Asn Gly Ser Lys Asp Asn Ser Leu Asp Met Leu Gly 
                85                  90                  95


Thr Asp Ile Trp Ala Ala Asn Thr Phe Asp Ser Phe Ser Gly Ala Thr 
            100                 105                 110


Trp Asp Leu Gln Pro Glu Lys Leu Asp Phe Thr Gln Phe His Arg Lys 
        115                 120                 125


Val Arg His Thr Pro Lys Gln Pro Leu Pro His Ile Asp Arg Glu Gly 
    130                 135                 140


Cys Gly Lys Gly Lys Leu Glu Asp Gly Asp Gly Ile Asn Leu Asn Asp 
145                 150                 155                 160


Ile Glu Lys Val Leu Pro Ala Trp Gln Gly Tyr His Pro Met Pro His 
                165                 170                 175


Glu Val Glu Ile Ala His Thr Lys Lys Leu Phe Arg Arg Arg Arg Asn 
            180                 185                 190


Asp Arg Arg Arg Gln Gln Arg Pro Pro Gly Gly Asn Lys Pro Gln Gln 
        195                 200                 205


His Gly Asp His Gln Pro Gly Ser Ala Lys His Asn Arg Asp His Gln 
    210                 215                 220


Lys Ser Tyr Gln Gly Gly Ser Ala Pro His Pro Ser Gly Arg Pro Thr 
225                 230                 235                 240


His His Gly Tyr Ser Gln Asn Arg Arg Trp His His Gly Asn Met Lys 
                245                 250                 255


His Pro Pro Gly Asp Lys Gly Glu Ala Gly Ala His Arg Asn Ala Lys 
            260                 265                 270


Glu Thr Met Thr Ile Glu Asn Pro Lys Leu Glu Asp Thr Ala Gly Asp 
        275                 280                 285


Thr Gly His Ser Ser Leu Glu Ala Pro Arg Ser Pro Asp Thr Leu Ala 
    290                 295                 300


Pro Val Ala Ser Glu Arg Leu Pro Pro Gln Gln Ser Gly Gly Pro Glu 
305                 310                 315                 320


Val Glu Thr Lys Arg Lys Asp Ser Ile Leu Pro Glu Arg Ile Gly Glu 
                325                 330                 335


Arg Pro Lys Ile Thr Leu Leu Gln Ser Ser Lys Asp Arg Leu Arg Arg 
            340                 345                 350


Arg Leu Lys Glu Lys Val Pro Asp Glu Val Ala Val Glu Thr Thr Thr 
        355                 360                 365


Pro Gln Gln Asn Lys Met Asp Lys Leu Ile Glu Ile Leu Asn Ser Met 
    370                 375                 380


Arg Asn Asn Ser Ser Asp Val Asp Thr Lys Leu Thr Thr Phe Met Glu 
385                 390                 395                 400


Glu Ala Gln Asn Ser Thr Asn Ser Glu Glu Met Leu Gly Glu Ile Val 
                405                 410                 415


Arg Thr Ile Tyr Gln Lys Ala Val Ser Asp Arg Ser Phe Ala Phe Thr 
            420                 425                 430


Ala Ala Lys Leu Cys Asp Lys Met Ala Leu Phe Met Val Glu Gly Thr 
        435                 440                 445


Lys Phe Arg Ser Leu Leu Leu Asn Met Leu Gln Lys Asp Phe Thr Val 
    450                 455                 460


Arg Glu Glu Leu Gln Gln Gln Asp Val Glu Arg Trp Leu Gly Phe Ile 
465                 470                 475                 480


Thr Phe Leu Cys Glu Val Phe Gly Thr Met Arg Ser Ser Thr Gly Glu 
                485                 490                 495


Pro Phe Arg Val Leu Val Cys Pro Ile Tyr Thr Cys Leu Arg Glu Leu 
            500                 505                 510


Leu Gln Ser Gln Asp Val Lys Glu Asp Ala Val Leu Cys Cys Ser Met 
        515                 520                 525


Glu Leu Gln Ser Thr Gly Arg Leu Leu Glu Glu Gln Leu Pro Glu Met 
    530                 535                 540


Met Thr Glu Leu Leu Ala Ser Ala Arg Asp Lys Met Leu Cys Pro Ser 
545                 550                 555                 560


Glu Ser Met Leu Thr Arg Ser Leu Leu Leu Glu Val Ile Glu Leu His 
                565                 570                 575


Ala Asn Ser Trp Asn Pro Leu Thr Pro Pro Ile Thr Gln Tyr Tyr Asn 
            580                 585                 590


Arg Thr Ile Gln Lys Leu Thr Ala 
        595                 600


<210>  9058
<211>  465
<212>  DNA
<213>  Homo sapiens

<400>  9058
catccttggc acccctatac ctgagcctgc cctcatctga ccctctcttc ttcaccagcc     60

ccatcgcaag tatacccagc tttatcctcc acatcagggg ctgaggtgac aacatgtcgg    120

taggaggaat ccttgcaggt gatctgctgg aaaaggagca cttccaggga ggcttccccc    180

tgccacccag tgtgcttcgg tgtcagcgcc cgccgctgca gaggttctgc acgcagggaa    240

caaactcctc tccctgtcgg cctctgccca gcacgctgtg gatggttcat ctgccacaca    300

cacaaagcag tgcgctggaa ggaaagatct ggaacactga gcccagggct tcgccccatc    360

cagggccact tggataccat ggattgagat ggcagggcca cagaacgcaa tccacctgga    420

ccctggagtc cccaaggagc taccctggag accagctgga ccctc                    465


<210>  9059
<211>  116
<212>  PRT
<213>  Homo sapiens

<400>  9059

Met Ser Val Gly Gly Ile Leu Ala Gly Asp Leu Leu Glu Lys Glu His 
1               5                   10                  15


Phe Gln Gly Gly Phe Pro Leu Pro Pro Ser Val Leu Arg Cys Gln Arg 
            20                  25                  30


Pro Pro Leu Gln Arg Phe Cys Thr Gln Gly Thr Asn Ser Ser Pro Cys 
        35                  40                  45


Arg Pro Leu Pro Ser Thr Leu Trp Met Val His Leu Pro His Thr Gln 
    50                  55                  60


Ser Ser Ala Leu Glu Gly Lys Ile Trp Asn Thr Glu Pro Arg Ala Ser 
65                  70                  75                  80


Pro His Pro Gly Pro Leu Gly Tyr His Gly Leu Arg Trp Gln Gly His 
                85                  90                  95


Arg Thr Gln Ser Thr Trp Thr Leu Glu Ser Pro Arg Ser Tyr Pro Gly 
            100                 105                 110


Asp Gln Leu Asp 
        115


<210>  9060
<211>  7324
<212>  DNA
<213>  Homo sapiens

<400>  9060
ggccaacgct ggttctatcc ctgcttgttg cttttttttt tccctccgct tcttgcgacg     60

gagactgctg tccaggaagt gcgcagtagt gattctagag aggctggaag ctctcctggc    120

gacgctgggg ccgcgaaggg ctcacgtaat gactcctact cctggtgagc gcaggcgttg    180

cggaactcac cgtcccacag gacgtgtttc cgggggtaca ttaattgtgg ctggacgcag    240

tggcgcggca gtttaattct ccggcggctg cagattgacg ggacgagatg gtcctggcag    300

ggctcatcag gaaactcggt catcagctgg ccgagatcag ggagcgcgct ctcaagagta    360

ttctctgcaa gattgagcac aacttaatct gctacgctga tctcattcag gagaggcaac    420

tttttcttca tttgctggaa tggttcaatt tcccgtccgt tccgatgaag gaagaggttc    480

tgaacctgtt aagcagattg gttaagtatc ccccagcagt ccaacatttg gttgacgttg    540

gtgcagtaga gttcttatct aagcttcggt ctaatgtgga gccaaatctg caggctgaaa    600

ttgatggcat tctggatgga ctttttcttc ttccttcgga agttcctgca ctatcttctg    660

cctcatacca aaccaatcaa actgaattgt caaaaaaccc tgaaatctta acaggatatt    720

ttccccaaga caaaagtaat ttccagcaga tggaagtgcc gccacgacca gtggtaaatc    780

agactgtgaa gtgcttgaag ttttctacat ttccttggct acccctgacc accacagaca    840

gacatgtcct ctcctctaat gaaagctctt taagaagtag taaccacact ttaatctgga    900

acacctgtga actattgaag gatgttatca tgcaagattt tcctgctgag attttccttc    960

aaaggccaaa aattgttcag agccttttat ctctgttgaa actggccttt ggagatggaa   1020

agcatcgcct ggcattacag tcggtgtcct gcctgcagca gctgtgcatg tatttaagaa   1080

acagacttaa ctttcaccga gatccaggtt ttttctccaa taaacacgac acagtttccc   1140

aaaattcttc tttgtcttat tgtcatgaag caagaggtac tcatcattcc cagaatcctt   1200

ccccaggaag cagcagccct cggccttctg tggttgggcg cacaggccag cgacccagag   1260

gagatggcca ggactgggat gcagcgtcct ctagtggaag tagtagtcat gctcatgtaa   1320

actccaggat atccgttcat tcacctttgg atatgggaca catagatctg ccagagctgg   1380

aaactgaaga cacattggaa ctacaattcc agcagctcag tcttccccag ttttgtgtct   1440

ccattctgga atcagctgtt cctctcttaa gaacaggtag cagacaagtg ataataagag   1500

ttctggaatt gcttacagag gatatgacac ttattggtga agcaatttca acagatatct   1560

gggatgacag cagccttttt ggtatagata tgaaggagaa actactcctg gtgttgggag   1620

cccttggaga aaccatgtgc taccataaaa gtagtatcag tttggagcag ccagaggtga   1680

tgcttgtgca ccacagaatg gcctttatca gcatttccct gtttgcagtt cgactgctac   1740

aaacgcttct ccctgttgaa aaggcaagcg agtttttatc agagcctatg tcaacagcat   1800

tatttctcct ttctttggac atgcctattt ctttggaata tccaaatatt catgaagctg   1860

ttgtggccta tttggaacag ctgaattctg aaaactacag tatttataaa cgaactgcag   1920

aggccgttta ttcaattgaa tgcacctgta acttcctgtc tgatattggg aaagagggag   1980

agaagaatct cttagaatta gtggagctgg cagaccaagc cttgcgtagc ttttcctatc   2040

atcagcattt cccgctaata aaggaaatca tcagcatttg ttcaaagatc tggaaatctg   2100

ctcaggccag tccattacta caaggagaaa gtcagaaggt gcttctccat atgttgtctc   2160

acccattgcc acgagtgaaa gctgaaactt accactgctg tctggaaatc acgaaggaat   2220

gtttaggtgt ccataatgtc actaaacccg tgtcttcact ttgcaatgga attcattttc   2280

tacttcatcc aaaagttctg tatgaaatct ctgtatttgg cattcaagag cccgaaagtg   2340

aggtgaacac tgctgccaag gccattctgt tatacctgct tcagggacga ttgatgatga   2400

cagcattgac ctggaacaag tttattgaat ctctctgtcc tgtcatccca atactacagg   2460

gctatgccga cacagaagat cctctgggta actgcattct ccttctaagc aaagcaagtt   2520

ctgacacaga agagatgctt ccgtgtacta cccgattaaa gtccatgctg cgacttttgc   2580

tagtgaaaaa gccatcggtc cgttcgctag cattaaagct tttagcattc catcttacca   2640

gtgaagaagg ggctgataca aagcgtcctc taatagacgc cagagttctc tccagagtta   2700

ctgatttatt cattgggaag aaacctattg aactcagact ggatgacaga agagagctgg   2760

ttattaagtt ggagactgtt gaaaaggtat atgaaatctt cacctcagat gatgttgatc   2820

tcgttttgag aaagtcagct gctgaacagt tagctgtgat tatgcaagat attaaaatgc   2880

atgctgtggt gaaaaagtta tgcttaattg acaaaataat tgagtattta aatgaatgtg   2940

tgagtcaaga tggcaaggtt gtagaatgtt tggtacaacc atgcctcaca ctcttgagga   3000

aggttttatg tggtgatcca gtcatgcgtg tttcgctctc gcaacagtct tctcttttga   3060

ccgtgttatt cagagtttcc ttaatatttc atgaagattg tagtgtcgtg actgaagttg   3120

gagcactatt ttgtcttcta ttatttgatg aagtatcgag aatggatatg tggtctgtta   3180

atccttccaa taaaccttct ttgccatcgg tcttcagttt gcctgtttcc gtttttagaa   3240

ggtaccatct acctgttcat gtaattggac accatgctgt gagtccttac tccatagttt   3300

tgcccttatc tgctgattgt ttggccttga agccggtgtc agatatgctg agaatagctt   3360

ggaacctgtc atggtatcat gggagtgata atctgttgaa gcaaatgaac tctgaaacta   3420

aaacgcaaga aattttagat gcattgaagt tatctacaga ggacatcctc actctgaaga   3480

taacacacat ggctagtggg ctgcaggact gcctccattc cattgttcag gctgcaaccc   3540

acagggaagt tagggctgct gtcaccagga tgagttttta tcttctgaat gacagattgt   3600

ctttaaaggg ttgccctggt ccatgtgggg ttaccttgaa gtccttggct tggcacaccg   3660

cactaaacag gtttttacag gtgcttcctg cttgcactga agatgagaaa ctgctaatag   3720

atatcataca ttttttaaat aaattaataa aggaacaaag aaaaaattct tcactagaac   3780

ttctaaactg gattctcgaa ttacttctta gacatagtgc aaacccactg ttagacctct   3840

tggttctgac agagtcacag gcacgagaag aaacagatga tatccggact gctgtcaggc   3900

aacaacttca gaaagaactg attgctcttt ttgatacctt gctgctcaat ttcatggaag   3960

ttactgacag gaaatgctcg gaacttcttt acgtttttca aacgcagctg gctctgaaac   4020

tgctccagtg tctgaaagtg acggatgcgc ctcatttcta tggcctgccg tcccttgagc   4080

ggaccttacg agggatggct aacctcactg cgtttccggg atggagctca cactctcctc   4140

tcacaaagcc tctagatatc tgtgtgaagt acttgtcagg tctccttgag gtcattactt   4200

ctttttatgt ggagcgtgga ggaaatgcta tgtccttcat gggaaaaggt gttacaaaga   4260

gcacaattct ttgcttgctt cacttatccc atgagatgat ggcccaggct gggagcttgg   4320

agtggatgtc actttggttc ttgcctttgg gtagtcatag tgaagaacat attcctactc   4380

aacaaggatt ggcttggttg attccattat gggttgatcg ggacccagag gtgagattca   4440

cttcactggg attaggatca gcactgacca cccttgaaac gggctgtgtg gccttagcaa   4500

acagttgtca gaacatttcc ggtgggctct ggggaactgt ggtgaacatt cttctggacc   4560

agtcagaatg tagtatggtg cgccgggagg cggcatttat tcttcagaat ctccttgtaa   4620

ttccaatgcc tacagaaatt ataaaggatt atacttggca gggtccctgt gttcatgatg   4680

aggactctgg cctatcgctc attggaaaac ctgcccttca ggctctttta tatcactgcc   4740

atttttatga acatttgaat cagatggtaa agcattgtta cctaggacgg tgtatgtttg   4800

atttgaattt ttctgctttt gatagaaatt cagaaagcaa tgatttaaat ggtttagatg   4860

actcattcaa gttttggagg gctccatcta ggacaagtca ggatcgagat ccaagttctc   4920

tctccacctc agaaacaacg gtggcacctt cattggggag tactgaattt cagccacttg   4980

tgcagtcaac aacacttcta cctgaagcct cccatgacca gtttgtggct caaggtcacc   5040

aggaaagtac atcaccacgg ccacctcatg attcatctct ttctgctccc ctgcccaaac   5100

tgtgtgtttt tgttactcca tctcttcttt cagcaatgtg cagcctcttg gacaacctct   5160

tgacgattgc tcccagagac actgcaaagg cttttcgaca agctcatctc atagaacttc   5220

tctgtagcat tgcagatgct accctcatac agacatgtgt ccaggaactc agagccctgc   5280

tgccttcatc acctccagct gaacacactc aggctcaggt ttcctttctc ctggaatacc   5340

tatcctcttt gtccaggctt ctgcagtcat gtttattggt ggagcctgac cttgtgattc   5400

aggatgagct tgtgaaacct cttatcacca atatcattgg aattctcacc atatgtacca   5460

aagatgtatt agataaagag ttaatatcag ctttttatca cacatggaca catttattta   5520

atcttctggc catgctcctg aggaaagctg gtgccatcac actcccgttt gttaccgtgg   5580

ccctggccaa gcactggaca gcggcgattg atatgttctg cacatgtgca ggcttgtctg   5640

ccacgtgtcc tgccctgtat actgccagct tgcaattcct ttctgttctc ttgaccgaag   5700

aagcaaaagg gcatctccag gctaagagca aaacacattt atgctgtagt ccaacagtgg   5760

cttcacttct tgatgactct caggaaaatc agaaatctct agaacaactt agtgatgtaa   5820

tccttcagtg ctatgaaggg aaatcctcca aagatatcct gaaaagagta gctgcaaatg   5880

cattgatgtc actgctggct gtcagtagaa gagcacagaa acatgctttg aaagccaatc   5940

ttatagacaa ttgcatggag cagatgaaac acataaatgc acaactgaac ctagattctc   6000

tgaggcctgg gaaagcagca ttgaaaaaaa aggaggatgg tgttattaaa gagttaagca   6060

ttgccatgca gctcctaaga aactgtcttt atcaaaatga ggaatgtaaa gaagcagctc   6120

ttgaagctca ccttgtccct gtcttgcact ctctctggcc ttggattttg atggatgatt   6180

cattgatgca aatttctctg cagctccttt gtgtctatac tgcaaatttt ccaaatggtt   6240

gcagttctct ttgttggtca agttgtggac aacaccctgt tcaagctaca catagaggag   6300

ccgtgagcaa ctctctgatg ctgtgtatcc taaagttggc ttcccagatg ccactggaga   6360

acaccacggt tcagcagatg gtttttatgc ttctttcaaa cctggccttg tcgcatgact   6420

gtaaaggagt aattcagaag agtaacttct tacagaactt cctctctcta gcattgccaa   6480

aaggaggaaa taaacatcta agtaatctga ctattctttg gttgaagtta ctcctgaata   6540

tatcatctgg agaagatggg caacaaatga ttctgaggct tgatggctgt ctagacttac   6600

taacagagat gagcaaatac aagcacaaga gcagcccttt attgcctctt cttatctttc   6660

ataatgtttg cttcagtcct gcaaataaac ccaagatcct ggctaatgaa aaagtcatta   6720

ctgtgcttgc tgcctgtctg gaaagtgaga atcaaaatgc tcagaggatt ggagcagctg   6780

ccctttgggc tctgatttac aattatcaga aggcaaaaac agctttgaaa agcccatcag   6840

taaaaagaag agtggatgaa gcatactcct tagcaaagaa aactttccca aactcagaag   6900

caaaccctct aaatgcctat tatttgaaat gtcttgaaaa cctcgtgcag ctccttaatt   6960

cttcctgagt gccatgggat gctacacctt gaagctgaca gtcatcaaca ggggagctaa   7020

agttgaagcc agctgtgtgt agcagctgtt acctgaagac gtgctacctc tctacaaagt   7080

gttgatcccc ttctttccca tgagagagag aactggtgat actccaacac cgtccagttg   7140

tggcagctct ccagaagtaa tagcagctga caactttctg tgccttttcc tttctgttga   7200

aaaggcatag aaagttctgg gaacataaac atttttaccc ttttctatgc catttatttt   7260

gtaaaaatcc tatttaacag ttatttaata aaacaatatt tttagaaact aaaaattgac   7320

taat                                                                7324


<210>  9061
<211>  2226
<212>  PRT
<213>  Homo sapiens

<400>  9061

Met Val Leu Ala Gly Leu Ile Arg Lys Leu Gly His Gln Leu Ala Glu 
1               5                   10                  15


Ile Arg Glu Arg Ala Leu Lys Ser Ile Leu Cys Lys Ile Glu His Asn 
            20                  25                  30


Leu Ile Cys Tyr Ala Asp Leu Ile Gln Glu Arg Gln Leu Phe Leu His 
        35                  40                  45


Leu Leu Glu Trp Phe Asn Phe Pro Ser Val Pro Met Lys Glu Glu Val 
    50                  55                  60


Leu Asn Leu Leu Ser Arg Leu Val Lys Tyr Pro Pro Ala Val Gln His 
65                  70                  75                  80


Leu Val Asp Val Gly Ala Val Glu Phe Leu Ser Lys Leu Arg Ser Asn 
                85                  90                  95


Val Glu Pro Asn Leu Gln Ala Glu Ile Asp Gly Ile Leu Asp Gly Leu 
            100                 105                 110


Phe Leu Leu Pro Ser Glu Val Pro Ala Leu Ser Ser Ala Ser Tyr Gln 
        115                 120                 125


Thr Asn Gln Thr Glu Leu Ser Lys Asn Pro Glu Ile Leu Thr Gly Tyr 
    130                 135                 140


Phe Pro Gln Asp Lys Ser Asn Phe Gln Gln Met Glu Val Pro Pro Arg 
145                 150                 155                 160


Pro Val Val Asn Gln Thr Val Lys Cys Leu Lys Phe Ser Thr Phe Pro 
                165                 170                 175


Trp Leu Pro Leu Thr Thr Thr Asp Arg His Val Leu Ser Ser Asn Glu 
            180                 185                 190


Ser Ser Leu Arg Ser Ser Asn His Thr Leu Ile Trp Asn Thr Cys Glu 
        195                 200                 205


Leu Leu Lys Asp Val Ile Met Gln Asp Phe Pro Ala Glu Ile Phe Leu 
    210                 215                 220


Gln Arg Pro Lys Ile Val Gln Ser Leu Leu Ser Leu Leu Lys Leu Ala 
225                 230                 235                 240


Phe Gly Asp Gly Lys His Arg Leu Ala Leu Gln Ser Val Ser Cys Leu 
                245                 250                 255


Gln Gln Leu Cys Met Tyr Leu Arg Asn Arg Leu Asn Phe His Arg Asp 
            260                 265                 270


Pro Gly Phe Phe Ser Asn Lys His Asp Thr Val Ser Gln Asn Ser Ser 
        275                 280                 285


Leu Ser Tyr Cys His Glu Ala Arg Gly Thr His His Ser Gln Asn Pro 
    290                 295                 300


Ser Pro Gly Ser Ser Ser Pro Arg Pro Ser Val Val Gly Arg Thr Gly 
305                 310                 315                 320


Gln Arg Pro Arg Gly Asp Gly Gln Asp Trp Asp Ala Ala Ser Ser Ser 
                325                 330                 335


Gly Ser Ser Ser His Ala His Val Asn Ser Arg Ile Ser Val His Ser 
            340                 345                 350


Pro Leu Asp Met Gly His Ile Asp Leu Pro Glu Leu Glu Thr Glu Asp 
        355                 360                 365


Thr Leu Glu Leu Gln Phe Gln Gln Leu Ser Leu Pro Gln Phe Cys Val 
    370                 375                 380


Ser Ile Leu Glu Ser Ala Val Pro Leu Leu Arg Thr Gly Ser Arg Gln 
385                 390                 395                 400


Val Ile Ile Arg Val Leu Glu Leu Leu Thr Glu Asp Met Thr Leu Ile 
                405                 410                 415


Gly Glu Ala Ile Ser Thr Asp Ile Trp Asp Asp Ser Ser Leu Phe Gly 
            420                 425                 430


Ile Asp Met Lys Glu Lys Leu Leu Leu Val Leu Gly Ala Leu Gly Glu 
        435                 440                 445


Thr Met Cys Tyr His Lys Ser Ser Ile Ser Leu Glu Gln Pro Glu Val 
    450                 455                 460


Met Leu Val His His Arg Met Ala Phe Ile Ser Ile Ser Leu Phe Ala 
465                 470                 475                 480


Val Arg Leu Leu Gln Thr Leu Leu Pro Val Glu Lys Ala Ser Glu Phe 
                485                 490                 495


Leu Ser Glu Pro Met Ser Thr Ala Leu Phe Leu Leu Ser Leu Asp Met 
            500                 505                 510


Pro Ile Ser Leu Glu Tyr Pro Asn Ile His Glu Ala Val Val Ala Tyr 
        515                 520                 525


Leu Glu Gln Leu Asn Ser Glu Asn Tyr Ser Ile Tyr Lys Arg Thr Ala 
    530                 535                 540


Glu Ala Val Tyr Ser Ile Glu Cys Thr Cys Asn Phe Leu Ser Asp Ile 
545                 550                 555                 560


Gly Lys Glu Gly Glu Lys Asn Leu Leu Glu Leu Val Glu Leu Ala Asp 
                565                 570                 575


Gln Ala Leu Arg Ser Phe Ser Tyr His Gln His Phe Pro Leu Ile Lys 
            580                 585                 590


Glu Ile Ile Ser Ile Cys Ser Lys Ile Trp Lys Ser Ala Gln Ala Ser 
        595                 600                 605


Pro Leu Leu Gln Gly Glu Ser Gln Lys Val Leu Leu His Met Leu Ser 
    610                 615                 620


His Pro Leu Pro Arg Val Lys Ala Glu Thr Tyr His Cys Cys Leu Glu 
625                 630                 635                 640


Ile Thr Lys Glu Cys Leu Gly Val His Asn Val Thr Lys Pro Val Ser 
                645                 650                 655


Ser Leu Cys Asn Gly Ile His Phe Leu Leu His Pro Lys Val Leu Tyr 
            660                 665                 670


Glu Ile Ser Val Phe Gly Ile Gln Glu Pro Glu Ser Glu Val Asn Thr 
        675                 680                 685


Ala Ala Lys Ala Ile Leu Leu Tyr Leu Leu Gln Gly Arg Leu Met Met 
    690                 695                 700


Thr Ala Leu Thr Trp Asn Lys Phe Ile Glu Ser Leu Cys Pro Val Ile 
705                 710                 715                 720


Pro Ile Leu Gln Gly Tyr Ala Asp Thr Glu Asp Pro Leu Gly Asn Cys 
                725                 730                 735


Ile Leu Leu Leu Ser Lys Ala Ser Ser Asp Thr Glu Glu Met Leu Pro 
            740                 745                 750


Cys Thr Thr Arg Leu Lys Ser Met Leu Arg Leu Leu Leu Val Lys Lys 
        755                 760                 765


Pro Ser Val Arg Ser Leu Ala Leu Lys Leu Leu Ala Phe His Leu Thr 
    770                 775                 780


Ser Glu Glu Gly Ala Asp Thr Lys Arg Pro Leu Ile Asp Ala Arg Val 
785                 790                 795                 800


Leu Ser Arg Val Thr Asp Leu Phe Ile Gly Lys Lys Pro Ile Glu Leu 
                805                 810                 815


Arg Leu Asp Asp Arg Arg Glu Leu Val Ile Lys Leu Glu Thr Val Glu 
            820                 825                 830


Lys Val Tyr Glu Ile Phe Thr Ser Asp Asp Val Asp Leu Val Leu Arg 
        835                 840                 845


Lys Ser Ala Ala Glu Gln Leu Ala Val Ile Met Gln Asp Ile Lys Met 
    850                 855                 860


His Ala Val Val Lys Lys Leu Cys Leu Ile Asp Lys Ile Ile Glu Tyr 
865                 870                 875                 880


Leu Asn Glu Cys Val Ser Gln Asp Gly Lys Val Val Glu Cys Leu Val 
                885                 890                 895


Gln Pro Cys Leu Thr Leu Leu Arg Lys Val Leu Cys Gly Asp Pro Val 
            900                 905                 910


Met Arg Val Ser Leu Ser Gln Gln Ser Ser Leu Leu Thr Val Leu Phe 
        915                 920                 925


Arg Val Ser Leu Ile Phe His Glu Asp Cys Ser Val Val Thr Glu Val 
    930                 935                 940


Gly Ala Leu Phe Cys Leu Leu Leu Phe Asp Glu Val Ser Arg Met Asp 
945                 950                 955                 960


Met Trp Ser Val Asn Pro Ser Asn Lys Pro Ser Leu Pro Ser Val Phe 
                965                 970                 975


Ser Leu Pro Val Ser Val Phe Arg Arg Tyr His Leu Pro Val His Val 
            980                 985                 990


Ile Gly His His Ala Val Ser Pro Tyr Ser Ile Val Leu Pro Leu Ser 
        995                 1000                1005


Ala Asp Cys Leu Ala Leu Lys Pro Val Ser Asp Met Leu Arg Ile Ala 
    1010                1015                1020


Trp Asn Leu Ser Trp Tyr His Gly Ser Asp Asn Leu Leu Lys Gln Met 
1025                1030                1035                1040


Asn Ser Glu Thr Lys Thr Gln Glu Ile Leu Asp Ala Leu Lys Leu Ser 
                1045                1050                1055


Thr Glu Asp Ile Leu Thr Leu Lys Ile Thr His Met Ala Ser Gly Leu 
            1060                1065                1070


Gln Asp Cys Leu His Ser Ile Val Gln Ala Ala Thr His Arg Glu Val 
        1075                1080                1085


Arg Ala Ala Val Thr Arg Met Ser Phe Tyr Leu Leu Asn Asp Arg Leu 
    1090                1095                1100


Ser Leu Lys Gly Cys Pro Gly Pro Cys Gly Val Thr Leu Lys Ser Leu 
1105                1110                1115                1120


Ala Trp His Thr Ala Leu Asn Arg Phe Leu Gln Val Leu Pro Ala Cys 
                1125                1130                1135


Thr Glu Asp Glu Lys Leu Leu Ile Asp Ile Ile His Phe Leu Asn Lys 
            1140                1145                1150


Leu Ile Lys Glu Gln Arg Lys Asn Ser Ser Leu Glu Leu Leu Asn Trp 
        1155                1160                1165


Ile Leu Glu Leu Leu Leu Arg His Ser Ala Asn Pro Leu Leu Asp Leu 
    1170                1175                1180


Leu Val Leu Thr Glu Ser Gln Ala Arg Glu Glu Thr Asp Asp Ile Arg 
1185                1190                1195                1200


Thr Ala Val Arg Gln Gln Leu Gln Lys Glu Leu Ile Ala Leu Phe Asp 
                1205                1210                1215


Thr Leu Leu Leu Asn Phe Met Glu Val Thr Asp Arg Lys Cys Ser Glu 
            1220                1225                1230


Leu Leu Tyr Val Phe Gln Thr Gln Leu Ala Leu Lys Leu Leu Gln Cys 
        1235                1240                1245


Leu Lys Val Thr Asp Ala Pro His Phe Tyr Gly Leu Pro Ser Leu Glu 
    1250                1255                1260


Arg Thr Leu Arg Gly Met Ala Asn Leu Thr Ala Phe Pro Gly Trp Ser 
1265                1270                1275                1280


Ser His Ser Pro Leu Thr Lys Pro Leu Asp Ile Cys Val Lys Tyr Leu 
                1285                1290                1295


Ser Gly Leu Leu Glu Val Ile Thr Ser Phe Tyr Val Glu Arg Gly Gly 
            1300                1305                1310


Asn Ala Met Ser Phe Met Gly Lys Gly Val Thr Lys Ser Thr Ile Leu 
        1315                1320                1325


Cys Leu Leu His Leu Ser His Glu Met Met Ala Gln Ala Gly Ser Leu 
    1330                1335                1340


Glu Trp Met Ser Leu Trp Phe Leu Pro Leu Gly Ser His Ser Glu Glu 
1345                1350                1355                1360


His Ile Pro Thr Gln Gln Gly Leu Ala Trp Leu Ile Pro Leu Trp Val 
                1365                1370                1375


Asp Arg Asp Pro Glu Val Arg Phe Thr Ser Leu Gly Leu Gly Ser Ala 
            1380                1385                1390


Leu Thr Thr Leu Glu Thr Gly Cys Val Ala Leu Ala Asn Ser Cys Gln 
        1395                1400                1405


Asn Ile Ser Gly Gly Leu Trp Gly Thr Val Val Asn Ile Leu Leu Asp 
    1410                1415                1420


Gln Ser Glu Cys Ser Met Val Arg Arg Glu Ala Ala Phe Ile Leu Gln 
1425                1430                1435                1440


Asn Leu Leu Val Ile Pro Met Pro Thr Glu Ile Ile Lys Asp Tyr Thr 
                1445                1450                1455


Trp Gln Gly Pro Cys Val His Asp Glu Asp Ser Gly Leu Ser Leu Ile 
            1460                1465                1470


Gly Lys Pro Ala Leu Gln Ala Leu Leu Tyr His Cys His Phe Tyr Glu 
        1475                1480                1485


His Leu Asn Gln Met Val Lys His Cys Tyr Leu Gly Arg Cys Met Phe 
    1490                1495                1500


Asp Leu Asn Phe Ser Ala Phe Asp Arg Asn Ser Glu Ser Asn Asp Leu 
1505                1510                1515                1520


Asn Gly Leu Asp Asp Ser Phe Lys Phe Trp Arg Ala Pro Ser Arg Thr 
                1525                1530                1535


Ser Gln Asp Arg Asp Pro Ser Ser Leu Ser Thr Ser Glu Thr Thr Val 
            1540                1545                1550


Ala Pro Ser Leu Gly Ser Thr Glu Phe Gln Pro Leu Val Gln Ser Thr 
        1555                1560                1565


Thr Leu Leu Pro Glu Ala Ser His Asp Gln Phe Val Ala Gln Gly His 
    1570                1575                1580


Gln Glu Ser Thr Ser Pro Arg Pro Pro His Asp Ser Ser Leu Ser Ala 
1585                1590                1595                1600


Pro Leu Pro Lys Leu Cys Val Phe Val Thr Pro Ser Leu Leu Ser Ala 
                1605                1610                1615


Met Cys Ser Leu Leu Asp Asn Leu Leu Thr Ile Ala Pro Arg Asp Thr 
            1620                1625                1630


Ala Lys Ala Phe Arg Gln Ala His Leu Ile Glu Leu Leu Cys Ser Ile 
        1635                1640                1645


Ala Asp Ala Thr Leu Ile Gln Thr Cys Val Gln Glu Leu Arg Ala Leu 
    1650                1655                1660


Leu Pro Ser Ser Pro Pro Ala Glu His Thr Gln Ala Gln Val Ser Phe 
1665                1670                1675                1680


Leu Leu Glu Tyr Leu Ser Ser Leu Ser Arg Leu Leu Gln Ser Cys Leu 
                1685                1690                1695


Leu Val Glu Pro Asp Leu Val Ile Gln Asp Glu Leu Val Lys Pro Leu 
            1700                1705                1710


Ile Thr Asn Ile Ile Gly Ile Leu Thr Ile Cys Thr Lys Asp Val Leu 
        1715                1720                1725


Asp Lys Glu Leu Ile Ser Ala Phe Tyr His Thr Trp Thr His Leu Phe 
    1730                1735                1740


Asn Leu Leu Ala Met Leu Leu Arg Lys Ala Gly Ala Ile Thr Leu Pro 
1745                1750                1755                1760


Phe Val Thr Val Ala Leu Ala Lys His Trp Thr Ala Ala Ile Asp Met 
                1765                1770                1775


Phe Cys Thr Cys Ala Gly Leu Ser Ala Thr Cys Pro Ala Leu Tyr Thr 
            1780                1785                1790


Ala Ser Leu Gln Phe Leu Ser Val Leu Leu Thr Glu Glu Ala Lys Gly 
        1795                1800                1805


His Leu Gln Ala Lys Ser Lys Thr His Leu Cys Cys Ser Pro Thr Val 
    1810                1815                1820


Ala Ser Leu Leu Asp Asp Ser Gln Glu Asn Gln Lys Ser Leu Glu Gln 
1825                1830                1835                1840


Leu Ser Asp Val Ile Leu Gln Cys Tyr Glu Gly Lys Ser Ser Lys Asp 
                1845                1850                1855


Ile Leu Lys Arg Val Ala Ala Asn Ala Leu Met Ser Leu Leu Ala Val 
            1860                1865                1870


Ser Arg Arg Ala Gln Lys His Ala Leu Lys Ala Asn Leu Ile Asp Asn 
        1875                1880                1885


Cys Met Glu Gln Met Lys His Ile Asn Ala Gln Leu Asn Leu Asp Ser 
    1890                1895                1900


Leu Arg Pro Gly Lys Ala Ala Leu Lys Lys Lys Glu Asp Gly Val Ile 
1905                1910                1915                1920


Lys Glu Leu Ser Ile Ala Met Gln Leu Leu Arg Asn Cys Leu Tyr Gln 
                1925                1930                1935


Asn Glu Glu Cys Lys Glu Ala Ala Leu Glu Ala His Leu Val Pro Val 
            1940                1945                1950


Leu His Ser Leu Trp Pro Trp Ile Leu Met Asp Asp Ser Leu Met Gln 
        1955                1960                1965


Ile Ser Leu Gln Leu Leu Cys Val Tyr Thr Ala Asn Phe Pro Asn Gly 
    1970                1975                1980


Cys Ser Ser Leu Cys Trp Ser Ser Cys Gly Gln His Pro Val Gln Ala 
1985                1990                1995                2000


Thr His Arg Gly Ala Val Ser Asn Ser Leu Met Leu Cys Ile Leu Lys 
                2005                2010                2015


Leu Ala Ser Gln Met Pro Leu Glu Asn Thr Thr Val Gln Gln Met Val 
            2020                2025                2030


Phe Met Leu Leu Ser Asn Leu Ala Leu Ser His Asp Cys Lys Gly Val 
        2035                2040                2045


Ile Gln Lys Ser Asn Phe Leu Gln Asn Phe Leu Ser Leu Ala Leu Pro 
    2050                2055                2060


Lys Gly Gly Asn Lys His Leu Ser Asn Leu Thr Ile Leu Trp Leu Lys 
2065                2070                2075                2080


Leu Leu Leu Asn Ile Ser Ser Gly Glu Asp Gly Gln Gln Met Ile Leu 
                2085                2090                2095


Arg Leu Asp Gly Cys Leu Asp Leu Leu Thr Glu Met Ser Lys Tyr Lys 
            2100                2105                2110


His Lys Ser Ser Pro Leu Leu Pro Leu Leu Ile Phe His Asn Val Cys 
        2115                2120                2125


Phe Ser Pro Ala Asn Lys Pro Lys Ile Leu Ala Asn Glu Lys Val Ile 
    2130                2135                2140


Thr Val Leu Ala Ala Cys Leu Glu Ser Glu Asn Gln Asn Ala Gln Arg 
2145                2150                2155                2160


Ile Gly Ala Ala Ala Leu Trp Ala Leu Ile Tyr Asn Tyr Gln Lys Ala 
                2165                2170                2175


Lys Thr Ala Leu Lys Ser Pro Ser Val Lys Arg Arg Val Asp Glu Ala 
            2180                2185                2190


Tyr Ser Leu Ala Lys Lys Thr Phe Pro Asn Ser Glu Ala Asn Pro Leu 
        2195                2200                2205


Asn Ala Tyr Tyr Leu Lys Cys Leu Glu Asn Leu Val Gln Leu Leu Asn 
    2210                2215                2220


Ser Ser 
2225


<210>  9062
<211>  2574
<212>  DNA
<213>  Homo sapiens

<400>  9062
ggccaacgct ggttctatcc ctgcttgttg cttttttttt tccctccgct tcttgcgacg     60

gagactgctg tccaggaagt gcgcagtagt gattctagag aggctggaag ctctcctggc    120

gacgctgggg ccgcgaaggg ctcacgtaat gactcctact cctggtgagc gcaggcgttg    180

cggaactcac cgtcccacag gacgtgtttc cgggggtaca ttaattgtgg ctggacgcag    240

tggcgcggca gtttaattct ccggcggctg cagattgacg ggacgagatg gtcctggcag    300

ggctcatcag gaaactcggt catcagctgg ccgagatcag ggagcgcgct ctcaagagta    360

ttctctgcaa gattgagcac aacttaatct gctacgctga tctcattcag gagaggcaac    420

tttttcttca tttgctggaa tggttcaatt tcccgtccgt tccgatgaag gaagaggttc    480

tgaacctgtt aagcagattg gttaagtatc ccccagcagt ccaacatttg gttgacgttg    540

gtgcagtaga gttcttatct aagcttcggt ctaatgtgga gccaaatctg caggctgaaa    600

ttgatggcat tctggatgga ctttttcttc ttccttcgga agttcctgca ctatcttctg    660

cctcatacca aaccaatcaa actgaattgt caaaaaaccc tgaaatctta acaggatatt    720

ttccccaaga caaaagtaat ttccagcaga tggaagtgcc gccacgacca gtggtaaatc    780

agactgtgaa gtgcttgaag ttttctacat ttccttggct acccctgacc accacagaca    840

gacatgtcct ctcctctaat gaaagctctt taagaagtag taaccacact ttaatctgga    900

acacctgtga actattgaag gatgttatca tgcaagattt tcctgctgag attttccttc    960

aaaggccaaa aattgttcag agccttttat ctctgttgaa actggccttt ggagatggaa   1020

agcatcgcct ggcattacag tcggtgtcct gcctgcagca gctgtgcatg tatttaagaa   1080

acagacttaa ctttcaccga gatccaggtt ttttctccaa taaacacgac acagtttccc   1140

aaaattcttc tttgtcttat tgtcatgaag caagaggtac tcatcattcc cagaatcctt   1200

ccccaggaag cagcagccct cggccttctg tggttgggcg cacaggccag cgacccagag   1260

gagatggcca ggactgggat gcagcgtcct ctagtggaag tagtagtcat gctcatgtaa   1320

actccaggat atccgttcat tcacctttgg atatgggaca catagatctg ccagagctgg   1380

aaactgaaga cacattggaa ctacaattcc agcagctcag tcttccccag ttttgtgtct   1440

ccattctgga atcagctgtt cctctcttaa gaacaggtag cagacaagtg ataataagag   1500

ttctggaatt gcttacagag gatatgacac ttattggtga agcaatttca acagatatct   1560

gggatgacag cagccttttt ggtatagata tgaaggagaa actactcctg gtgttgggag   1620

cccttggaga aaccatgtgc taccataaaa gtagtatcag tttggagcag ccagaggtga   1680

tgcttgtgca ccacagaatg gcctttatca gcatttccct gtttgcagtt cgactgctac   1740

aaacgcttct ccctgttgaa aaggcaagcg agtttttatc agagcctatg tcaacagcat   1800

tatttctcct ttctttggac atgcctattt ctttggaata tccaaatatt catgaagctg   1860

ttgtggccta tttggaacag ctgaattctg aaaactacag tatttataaa cgaactgcag   1920

aggccgttta ttcaattgaa tgcacctgta acttcctgtc tgatattggg aaagagggag   1980

agaagaatct cttagaatta gtggagctgg cagaccaagc cttgcgtagc ttttcctatc   2040

atcagcattt cccgctaata aaggaaatca tcagcatttg ttcaaagatg taatattttc   2100

tttcttaatg tgattacgtt attattggac acttagggtg tgtgtaaact tagaaacagt   2160

gaaagtgaaa ctgactgtat atctttgtta ttatttttta gtttaattgc ttttatatgt   2220

gtctgatttt taaagggtat atgtacagct gcattaggat acttaactgt tatattcaag   2280

attaaacttc aaaaatgtca tgcctacaat caaaatgaat aatccttgga tttttataca   2340

tttgtttttg gtatccatcc agactattca cacacattgt ttatttatct ttaaagtttt   2400

aattaataac ttaaactgag agttttgtaa cttttattac tttgtacctt tttcttatgt   2460

ggatttttag aaaagactgt gtattggtta atttattttg aggacatcag caaatttcta   2520

tttagaactt agtgtcttta ttgcttttgg aaagaataaa ttctgtgatg tgat         2574


<210>  9063
<211>  601
<212>  PRT
<213>  Homo sapiens

<400>  9063

Met Val Leu Ala Gly Leu Ile Arg Lys Leu Gly His Gln Leu Ala Glu 
1               5                   10                  15


Ile Arg Glu Arg Ala Leu Lys Ser Ile Leu Cys Lys Ile Glu His Asn 
            20                  25                  30


Leu Ile Cys Tyr Ala Asp Leu Ile Gln Glu Arg Gln Leu Phe Leu His 
        35                  40                  45


Leu Leu Glu Trp Phe Asn Phe Pro Ser Val Pro Met Lys Glu Glu Val 
    50                  55                  60


Leu Asn Leu Leu Ser Arg Leu Val Lys Tyr Pro Pro Ala Val Gln His 
65                  70                  75                  80


Leu Val Asp Val Gly Ala Val Glu Phe Leu Ser Lys Leu Arg Ser Asn 
                85                  90                  95


Val Glu Pro Asn Leu Gln Ala Glu Ile Asp Gly Ile Leu Asp Gly Leu 
            100                 105                 110


Phe Leu Leu Pro Ser Glu Val Pro Ala Leu Ser Ser Ala Ser Tyr Gln 
        115                 120                 125


Thr Asn Gln Thr Glu Leu Ser Lys Asn Pro Glu Ile Leu Thr Gly Tyr 
    130                 135                 140


Phe Pro Gln Asp Lys Ser Asn Phe Gln Gln Met Glu Val Pro Pro Arg 
145                 150                 155                 160


Pro Val Val Asn Gln Thr Val Lys Cys Leu Lys Phe Ser Thr Phe Pro 
                165                 170                 175


Trp Leu Pro Leu Thr Thr Thr Asp Arg His Val Leu Ser Ser Asn Glu 
            180                 185                 190


Ser Ser Leu Arg Ser Ser Asn His Thr Leu Ile Trp Asn Thr Cys Glu 
        195                 200                 205


Leu Leu Lys Asp Val Ile Met Gln Asp Phe Pro Ala Glu Ile Phe Leu 
    210                 215                 220


Gln Arg Pro Lys Ile Val Gln Ser Leu Leu Ser Leu Leu Lys Leu Ala 
225                 230                 235                 240


Phe Gly Asp Gly Lys His Arg Leu Ala Leu Gln Ser Val Ser Cys Leu 
                245                 250                 255


Gln Gln Leu Cys Met Tyr Leu Arg Asn Arg Leu Asn Phe His Arg Asp 
            260                 265                 270


Pro Gly Phe Phe Ser Asn Lys His Asp Thr Val Ser Gln Asn Ser Ser 
        275                 280                 285


Leu Ser Tyr Cys His Glu Ala Arg Gly Thr His His Ser Gln Asn Pro 
    290                 295                 300


Ser Pro Gly Ser Ser Ser Pro Arg Pro Ser Val Val Gly Arg Thr Gly 
305                 310                 315                 320


Gln Arg Pro Arg Gly Asp Gly Gln Asp Trp Asp Ala Ala Ser Ser Ser 
                325                 330                 335


Gly Ser Ser Ser His Ala His Val Asn Ser Arg Ile Ser Val His Ser 
            340                 345                 350


Pro Leu Asp Met Gly His Ile Asp Leu Pro Glu Leu Glu Thr Glu Asp 
        355                 360                 365


Thr Leu Glu Leu Gln Phe Gln Gln Leu Ser Leu Pro Gln Phe Cys Val 
    370                 375                 380


Ser Ile Leu Glu Ser Ala Val Pro Leu Leu Arg Thr Gly Ser Arg Gln 
385                 390                 395                 400


Val Ile Ile Arg Val Leu Glu Leu Leu Thr Glu Asp Met Thr Leu Ile 
                405                 410                 415


Gly Glu Ala Ile Ser Thr Asp Ile Trp Asp Asp Ser Ser Leu Phe Gly 
            420                 425                 430


Ile Asp Met Lys Glu Lys Leu Leu Leu Val Leu Gly Ala Leu Gly Glu 
        435                 440                 445


Thr Met Cys Tyr His Lys Ser Ser Ile Ser Leu Glu Gln Pro Glu Val 
    450                 455                 460


Met Leu Val His His Arg Met Ala Phe Ile Ser Ile Ser Leu Phe Ala 
465                 470                 475                 480


Val Arg Leu Leu Gln Thr Leu Leu Pro Val Glu Lys Ala Ser Glu Phe 
                485                 490                 495


Leu Ser Glu Pro Met Ser Thr Ala Leu Phe Leu Leu Ser Leu Asp Met 
            500                 505                 510


Pro Ile Ser Leu Glu Tyr Pro Asn Ile His Glu Ala Val Val Ala Tyr 
        515                 520                 525


Leu Glu Gln Leu Asn Ser Glu Asn Tyr Ser Ile Tyr Lys Arg Thr Ala 
    530                 535                 540


Glu Ala Val Tyr Ser Ile Glu Cys Thr Cys Asn Phe Leu Ser Asp Ile 
545                 550                 555                 560


Gly Lys Glu Gly Glu Lys Asn Leu Leu Glu Leu Val Glu Leu Ala Asp 
                565                 570                 575


Gln Ala Leu Arg Ser Phe Ser Tyr His Gln His Phe Pro Leu Ile Lys 
            580                 585                 590


Glu Ile Ile Ser Ile Cys Ser Lys Met 
        595                 600


<210>  9064
<211>  2847
<212>  DNA
<213>  Homo sapiens

<400>  9064
ttccaaataa ggtcacatgc acaggtacag gggttaggac atcaacttct ctcttggaag     60

aacagaattc aactgataca acactggagg ggtgaaaaca agacagagag agagagagag    120

agagagagag agatgagggg cccgcacatg ccctgctcat ctcaaaactt ctcgagaagc    180

aaatctaact tgcaggaact ttgagaaagg caggagaagc aaaaaagcaa aatgagattg    240

ttttcataac ttaaagaggc tgaaaatgat gaaactgggc tgagatgtgt tacaggagcc    300

tacacagcta gaaggataga ttcgaggtca tgctttgagc aaaagccatt aaaatacata    360

aataacattg tatcacactt ttgcctctca agttgagact gcctctaaat tgactagcgt    420

tacaaatatc ctaacagaaa actatcccta aaacctagaa agccatatta tgctttggca    480

atcatctgac catgtacaac aaatgtaatg aaaacggtaa acctgaacca aggcaaaccc    540

aacagtttaa tttaaaaact tgaagatact aagtattccc ttcaactgga cattcagaaa    600

cttcacgtgg ctacattgta tttcccccca cgagttgctt cagggttgtg aaattcactg    660

gactgtggag ggagccttaa acctttgtgg gtgattgacg tctaaagtac ctgagctttt    720

ctggttctgc tgaccctcag tctcctggac cctagaagaa gaatcagacc catccttcag    780

tctcatctct agaagcccag aataaaatga aaaagagatg ggttttcgcc atgttgccca    840

ggctggtctc aaacttgtga gctcaagaaa tccacctgcc ttagcctccc aaagtgctgg    900

gattacagga tgagccactg agcccagctg actccaagct tttctaatga ggtttctggg    960

ccacagagtg gagacagtcc ctatcctcaa aggatgctac agtgcattgt caaagaccaa   1020

tgcgtcaaaa tacttatgga agaaggtgcc caaaagttcg aagacagtta tctacacggg   1080

aggtgtaaga aaatcacctt ggaataccca tctcggaaga acaggtgtga atgcccttga   1140

atcacttgga gagcttctct tcgatgttaa attattgtag taacaccaag ctcaccaccc   1200

agaatgatgc agtcagcctc ccctggaagg aatgaaggtc gtagtctcct ctccatagat   1260

gtgtctcatt ttctatttaa aaaaaaaaat gtgaattcag gcactgcgtt tgaaaagttt   1320

ggcagcaaaa caaatgtcca gtccatgtcc tgggtcctag gggagggcaa aaaatggcct   1380

cctggcccat ggtgtggcac acacatgccc tcctctcctg gctgccttgt gcccaggccc   1440

agccagaggc ctgaaatgtg gccatgtatg gcaacacgga ccgtgaagcc cggagatctg   1500

cagcatcaag ccccatgcat gagcgaagag agcactgaca gcagaggata gtccttcctc   1560

tgagaaacac ggttcttaca gggttgggga caagaggcat tctgcagctg ggatcagcct   1620

cagcttggca ggagaggatc aagcacccta ggggactcag tgtggcagga agaactcaga   1680

gctccatcct gtggctgctc aggggctgaa gcagaggcat tgcctttgga ctgtccaatg   1740

ccctgaggat tttggatacg gtgagtcttt ctgctaaaga ggcatgtgag gtccttgggc   1800

aattgtttaa aataagaaca ggtgaccata tttgcacccc aatatgagga agagtttaca   1860

aaggcttcca ttatttccac aaaactacag aaacaggcct cgtgattcag gagactgaag   1920

ggacctggtg gacaagaata agagccaagt gaatcaaagg tttctttaag ggaacaaaca   1980

tcaggacaga atttcatgaa gtggtaacac aactagaaag gagcacagaa aaaccagtgc   2040

atcccgcttt tgtataatga agaccctgta aggggtaaca agactcagtc aaggtcaagt   2100

gaagcagatg ggtacaaacg cgacgcaatg caagcaaatg aaagtgatgc cgtgacctga   2160

ctgccgtggt tagaggactt cttatgctca agcacaaaga acagaccgta aggagcagct   2220

gtgatccagg gaaccggata ggaagatgtt gcctgggcca gaatgaccct acgaacagaa   2280

aaactgagat ctacagaagt ttatggaaaa gtacccatga tcacactgct gatatgtggc   2340

aaacctgagc tatagatacc aggctttaca gaagcagaat caggttgtgg ttgcagaaaa   2400

aataagaaca gcgaaagacg cgtggggcat cacatctcca tcttgcagga actggcagcg   2460

atggtccagg ccaacgcctc tcgaggtggc ctcctcctcc catgtgaggg aaggactcac   2520

caggggcttc cctgctggta gggctcagag acgttactgt tatttaactc caaacccatc   2580

accggcgcct gagatgcagg cttgtgtgcg gggcagatgg ccagctgtca gggaggacgt   2640

gagcacttca ctttcaagga ccggttctga ccctggagca cgcagggtgc ggcctggcgc   2700

tgagtcccgt gttactcacc tcaacgtgtt ttaacgctgt ttcctccttc ccatttgata   2760

acccacctct tcgacaaacg accttcaata tttgagtggt aacagaaacg gagccactgt   2820

ggcaataaat tgctcataag cttggac                                       2847


<210>  9065
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  9065

Met Leu Lys His Lys Glu Gln Thr Val Arg Ser Ser Cys Asp Pro Gly 
1               5                   10                  15


Asn Arg Ile Gly Arg Cys Cys Leu Gly Gln Asn Asp Pro Thr Asn Arg 
            20                  25                  30


Lys Thr Glu Ile Tyr Arg Ser Leu Trp Lys Ser Thr His Asp His Thr 
        35                  40                  45


Ala Asp Met Trp Gln Thr 
    50


<210>  9066
<211>  806
<212>  DNA
<213>  Homo sapiens

<400>  9066
ctgatgtatg agctgcacag aaagttcacc aaaccaccca aagccattgc cataggcatc     60

tgaactgcaa gccagcacaa gaagtcgatg ctttcataca ctttccaaga tgtcagaaca    120

aggttccaaa tcataataag aattcactcc ttacctagaa gtaaaaaaag aggacacact    180

tttgaaccgc tcacatgacc acaccattct gcggggacgt ccttgtgttg aggggaggtc    240

tgaagtccat ggaagaagac gcagtggctg ctggagctcg tgcagaggaa gggaccctca    300

gaaggacagg tgaactgtcg gtggcaggaa aaatggtggg cacatttcca gaatgacaaa    360

tgggagaagc aatcgtgaca tctccaggtg ggggaagcat aggaggaaga ggttgttctc    420

tcaggaagtt gcctcctagc ctccaacgag gcctttccta tcactgctca ttctcttctg    480

tgtgtggatt ggatactgcg gtcacccaga gaagctggtg cacaccaggc acatgaaggg    540

gcgatccttg tctccttccg actcatgcgc gtgtcttgat gtttaaactc agaaggatgt    600

ttaaactcgg ttgtctatga gacaaaatgg ctagtttttg gagggtctgg ggcattacat    660

tctgcagatt aagatttttg cccgatattg gccaagtcaa ggaaatagat gctaaggcca    720

aatgctttga aaaaccacaa actcctgttt ctgtgggaaa tgtttggcct gttgaatcaa    780

actcaataaa gaacagtaaa atctgt                                         806


<210>  9067
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  9067

Met Leu Ser Tyr Thr Phe Gln Asp Val Arg Thr Arg Phe Gln Ile Ile 
1               5                   10                  15


Ile Arg Ile His Ser Leu Pro Arg Ser Lys Lys Arg Gly His Thr Phe 
            20                  25                  30


Glu Pro Leu Thr 
        35


<210>  9068
<211>  600
<212>  DNA
<213>  Homo sapiens

<400>  9068
tgagctcctg gctggagaat tcgctcacaa gggtgatgtg atcatcttac gtgtaaaaga     60

aaaccgaatt tcacttctgg tggtgactat tgtctgattc atcattacag taaccaccca    120

aggaaaccct gcccacaaaa agcattcttc tggagaagta acagtttttg gtgacacaca    180

tgatggcaac aatgaacgct ttgtggcacg atgacctcta tgaaaaagag agatatacag    240

gttttgcttt tgttcactca actaattacc aacctttcat tatacctcta ctcggacatc    300

taaacttcag ttaagctcta tgtttaagtg ggatggatct tcaatttgcc tacctaagga    360

tttgaagtca ggtttacaga ggcatcattt tacaattatc aactttgata aatgcagatt    420

gtcatggaac taccaccaga atccagatag agaacatgct atcatccctg ttatatccct    480

ttgtggctaa tccaccacac tgttccatcc accaaagtcc ctagaagcca ctgatctgtt    540

ttatgtccct ctggttttgt ctttttcaaa gtctgaaata aatggaattg tggagtgtgt    600


<210>  9069
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  9069

Met Phe Lys Trp Asp Gly Ser Ser Ile Cys Leu Pro Lys Asp Leu Lys 
1               5                   10                  15


Ser Gly Leu Gln Arg His His Phe Thr Ile Ile Asn Phe Asp Lys Cys 
            20                  25                  30


Arg Leu Ser Trp Asn Tyr His Gln Asn Pro Asp Arg Glu His Ala Ile 
        35                  40                  45


Ile Pro Val Ile Ser Leu Cys Gly 
    50                  55


<210>  9070
<211>  594
<212>  DNA
<213>  Homo sapiens

<400>  9070
ataaagacat gatcatctgg aaacatctgc aagaaaatct accaaaatga agacacactc     60

acaaaatgac cttcctccta catcccagct cttgtcatct taaaggcatt cactccatgg    120

aggccccagg aggcgaatgg cttctctcat cttgggctgc agctttgctg atgacttctg    180

gctcctcatg gaaaacagaa gtgcagggca tgcttttcca ttaagctctt tctgctaaag    240

cagattcgaa gttaagagaa gcaggcactg ctcattcttg tccaacattc atggacaaag    300

aactctgggc ttcagtcttg tcaaccctcg tgcagggctc tgctcattag caggaatctt    360

cagatgactc atattcctgg gcatttgatc ttttgtgata agaagaacca gcctggctca    420

ctgactgagt gaacacttca gtggtctgta gtccctcagt tgcactggac acagttgagg    480

ccctcaggag ccacgcgggg tcagcggtgg tggcattggg cagagcagct caccgagttc    540

cagaagctgc atgccaccca ttccgagtct gtgaccctcc acagcctggc ccac          594


<210>  9071
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  9071

Met Thr Phe Leu Leu His Pro Ser Ser Cys His Leu Lys Gly Ile His 
1               5                   10                  15


Ser Met Glu Ala Pro Gly Gly Glu Trp Leu Leu Ser Ser Trp Ala Ala 
            20                  25                  30


Ala Leu Leu Met Thr Ser Gly Ser Ser Trp Lys Thr Glu Val Gln Gly 
        35                  40                  45


Met Leu Phe His 
    50


<210>  9072
<211>  392
<212>  DNA
<213>  Homo sapiens

<400>  9072
agttgctctc tgctggataa gtggtggcca agagaaccac gtgtgctggt ggaaaagcgc     60

tggacctgct gcccagcacc acagccgaca gcagcaaatg gccattgaac acttcaaaat    120

gcggttatca gtggatgcct caccttagaa aagtcccgta aaactgagga agattgtggg    180

aggtatcctt gggggtcatc tagaccagca ctccagcctg ccccaaatct acagatcaaa    240

aaagcaaagt ccagagaagt aacgtctcaa ggtcacataa gtcagtccct atcaacaaca    300

gcactaaaat caaggcttcc taaaaccagt cggatcattg ttccattata gcatatggta    360

attcttgtta gatggaaaac agaaatattt ag                                  392


<210>  9073
<211>  80
<212>  PRT
<213>  Homo sapiens

<400>  9073

Thr Leu Gln Asn Ala Val Ile Ser Gly Cys Leu Thr Leu Glu Lys Ser 
1               5                   10                  15


Arg Lys Thr Glu Glu Asp Cys Gly Arg Tyr Pro Trp Gly Ser Ser Arg 
            20                  25                  30


Pro Ala Leu Gln Pro Ala Pro Asn Leu Gln Ile Lys Lys Ala Lys Ser 
        35                  40                  45


Arg Glu Val Thr Ser Gln Gly His Ile Ser Gln Ser Leu Ser Thr Thr 
    50                  55                  60


Ala Leu Lys Ser Arg Leu Pro Lys Thr Ser Arg Ile Ile Val Pro Leu 
65                  70                  75                  80


<210>  9074
<211>  910
<212>  DNA
<213>  Homo sapiens

<400>  9074
aaggaggggc tatgaaatat cttcactcca ggttctttat gagctgcagt gtatcatttt     60

tatcagcaat tggaagcatg ctgcatgttt gactctgtgg actcctgctt tacacaacag    120

aacattccga tggtgtgcat gtgccatagt acgtatagaa attctaagaa ttcatataat    180

ttacctgcta aatcagggac tattacagtc tgctgtgtaa attcacattt tggcactctt    240

taaaaagtgg attattattg acccaataga ccataacagc tccaaagaag ccgttactgt    300

acatcgtgta aagccttcgt ggtgtgtgtt ttattgaagc tctgtagctg tcgggatctg    360

cttgtcaatc tagctgccat gcgcgtgcac caaatgcatt gctaaagatg ccttgtaaat    420

tgaagcttta gtcaaattac ccttgttctt gtccaataag ccatggtata aaattggata    480

tttccactgc agtttctttc tccacctcca gaattctatt tccctgtatt tatagaggtt    540

gaaattttga aatgtggata agggagtggt gatttgattt caagtttcaa aaaaaaaaaa    600

aaaaaaaaag caggaagaaa attgaagaca gtttttgctt tgcatgaaaa aacatctcaa    660

agaatgcatg aatttaccag cttccaggag gctgacaacg gtcacagtga gatttctcta    720

ctttaggctt ttgggaatcc aaataagatt tttatttaat tttctatgtg ctaattttgt    780

gtttttccac ctgtctgtcc tcttctttca tttaacaaaa aaatgaacat tggaacattt    840

gtcaggaaaa aaaaaaaact ttttagttac ttgtaccttc agtaaaaata aaataatact    900

ttgaggtctc                                                           910


<210>  9075
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  9075

Met Lys Lys His Leu Lys Glu Cys Met Asn Leu Pro Ala Ser Arg Arg 
1               5                   10                  15


Leu Thr Thr Val Thr Val Arg Phe Leu Tyr Phe Arg Leu Leu Gly Ile 
            20                  25                  30


Gln Ile Arg Phe Leu Phe Asn Phe Leu Cys Ala Asn Phe Val Phe Phe 
        35                  40                  45


His Leu Ser Val Leu Phe Phe His Leu Thr Lys Lys 
    50                  55                  60


<210>  9076
<211>  462
<212>  DNA
<213>  Homo sapiens

<400>  9076
tctgctgtcc tctggggaga atgcatttga actcatctca aaaagctggt tttctaccct     60

ggaggtctcc gatggctact gcgagaagaa agccatgtcc cgaaagcagt gatacagatt    120

ggcagccact gcagagatgc agaatgtcga agagtgtgtg tgttggaatt cctggacaga    180

cactgctctg aaagaaaaac cctctggttt tggaagtctg gctgggcaag gcaggcggag    240

gtcatggagg ggccggcgtg atggaatcct cggtgcagct gactgcgcag cccgacactg    300

gcgtggacac tgggacgcgt catgcaacat ccaaccagag cacactcacg aggacaaaca    360

tgggcccacc tatttaccat cagaaaaaca aaatcatgct ctttcacttt gaaagaaggg    420

ggaaactgga aagttattat ttgaaataaa atggaatttt ag                       462


<210>  9077
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  9077

Met Gln Asn Val Glu Glu Cys Val Cys Trp Asn Ser Trp Thr Asp Thr 
1               5                   10                  15


Ala Leu Lys Glu Lys Pro Ser Gly Phe Gly Ser Leu Ala Gly Gln Gly 
            20                  25                  30


Arg Arg Arg Ser Trp Arg Gly Arg Arg Asp Gly Ile Leu Gly Ala Ala 
        35                  40                  45


Asp Cys Ala Ala Arg His Trp Arg Gly His Trp Asp Ala Ser Cys Asn 
    50                  55                  60


Ile Gln Pro Glu His Thr His Glu Asp Lys His Gly Pro Thr Tyr Leu 
65                  70                  75                  80


Pro Ser Glu Lys Gln Asn His Ala Leu Ser Leu 
                85                  90


<210>  9078
<211>  1667
<212>  DNA
<213>  Homo sapiens

<400>  9078
tcattcactt accaagtatt tctctgcttt ctgccatgtc acgggcccat gatcccctgg     60

agattgaggg aaataagatc acaggagctc ccagtctgag tgagaaaagg cagctgctct    120

gtggtactgt gcactggacc tgggaatggc ctaaggagac aagcattgag ggctgagctc    180

agaagccagg gagaagagct cagaacccca ggagaggagc tcagaaccct gggagaggag    240

ctcagaaccc tgggagggct tggtaacctt cgaggatgtg gccgtggagt tcacccagga    300

ggagtgggcg ttgctggacc ctgcccaaag gacactgtac agggatgtga tgctggagaa    360

ctgcaggaac ctggcctcac tagggtgtcg tgttaataaa cccagtctga tatcccagtt    420

ggaacaagac aagaaggtgg tgacagagga aagaggaatt ctaccaagca cctgtccaga    480

tttggagact ctacttaaag ccaaatggtt aactcctaag aagaatgttt tcagaaaaga    540

acagtctaaa ggtgtaaaaa cggaaagaag tcatcgtgga gtgaaactca atgaatgtaa    600

tcagtgtttt aaagtcttca gcacgaaatc taacctaact cagcacaaga gaattcatac    660

tggagaaaaa ccctatgact gtagtcaatg tgggaagtcc ttcagtagca gatcttacct    720

tactattcat aagagaatcc ataatgggga gaaaccctat gaatgcaatc actgtgggaa    780

agcatttagt gatccctcat cccttagact gcatttgaga attcacactg gagaaaaacc    840

ctatgaatgt aaccagtgtt ttcacgtttt ccgcaccagt tgtaacctca aaagccacaa    900

gaggattcac acgggggaga atcaccatga atgtaatcag tgtggaaaag ctttcagcac    960

aaggtcctct ctcactgggc acaatagcat tcatacaggg gagaaacctt atgaatgtca   1020

cgattgtggg aaaaccttca ggaagagctc ctatctgaca cagcacgtaa gaactcatac   1080

tggagaaaaa ccctatgaat gtaacgagtg tgggaaatcc ttcagcagta gcttttctct   1140

tactgtgcac aagagaatac ataccggaga gaaaccctac gagtgcagtg actgtggaaa   1200

agcctttaat aatctctcag ctgtgaagaa acacttaaga actcacactg gagaaaaacc   1260

ctatgaatgt aatcattgtg ggaaatcctt cacaagtaac tcctatcttt ctgtgcacaa   1320

gagaatacat aatagatgga tatgaattac tgcaggaact tctggaggaa agcactcatt   1380

gatctttcat ccctaagata gtttgagaga gctcacactg gatatataag ttatttgttg   1440

cagcataaca aatgatcccc gcaaattttg tggcttcaaa cacgaaatgt ttattctcta   1500

acaatttcta cagatcagga attcaagaac agcttatctc tgtagttaca ctgcaggatc   1560

tctcatgcct ttacttacaa tcaagatgtc agccaaagct atagtcatct aacatcttta   1620

ctgatgaaca gtccacttcc aagatgactt attcacatgc ctggaaa                 1667


<210>  9079
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  9079

Met Leu Glu Asn Cys Arg Asn Leu Ala Ser Leu Gly Cys Arg Val Asn 
1               5                   10                  15


Lys Pro Ser Leu Ile Ser Gln Leu Glu Gln Asp Lys Lys Val Val Thr 
            20                  25                  30


Glu Glu Arg Gly Ile Leu Pro Ser Thr Cys Pro Asp Leu Glu Thr Leu 
        35                  40                  45


Leu Lys Ala Lys Trp Leu Thr Pro Lys Lys Asn Val Phe Arg Lys Glu 
    50                  55                  60


Gln Ser Lys Gly Val Lys Thr Glu Arg Ser His Arg Gly Val Lys Leu 
65                  70                  75                  80


Asn Glu Cys Asn Gln Cys Phe Lys Val Phe Ser Thr Lys Ser Asn Leu 
                85                  90                  95


Thr Gln His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Asp Cys Ser 
            100                 105                 110


Gln Cys Gly Lys Ser Phe Ser Ser Arg Ser Tyr Leu Thr Ile His Lys 
        115                 120                 125


Arg Ile His Asn Gly Glu Lys Pro Tyr Glu Cys Asn His Cys Gly Lys 
    130                 135                 140


Ala Phe Ser Asp Pro Ser Ser Leu Arg Leu His Leu Arg Ile His Thr 
145                 150                 155                 160


Gly Glu Lys Pro Tyr Glu Cys Asn Gln Cys Phe His Val Phe Arg Thr 
                165                 170                 175


Ser Cys Asn Leu Lys Ser His Lys Arg Ile His Thr Gly Glu Asn His 
            180                 185                 190


His Glu Cys Asn Gln Cys Gly Lys Ala Phe Ser Thr Arg Ser Ser Leu 
        195                 200                 205


Thr Gly His Asn Ser Ile His Thr Gly Glu Lys Pro Tyr Glu Cys His 
    210                 215                 220


Asp Cys Gly Lys Thr Phe Arg Lys Ser Ser Tyr Leu Thr Gln His Val 
225                 230                 235                 240


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Gly Lys 
                245                 250                 255


Ser Phe Ser Ser Ser Phe Ser Leu Thr Val His Lys Arg Ile His Thr 
            260                 265                 270


Gly Glu Lys Pro Tyr Glu Cys Ser Asp Cys Gly Lys Ala Phe Asn Asn 
        275                 280                 285


Leu Ser Ala Val Lys Lys His Leu Arg Thr His Thr Gly Glu Lys Pro 
    290                 295                 300


Tyr Glu Cys Asn His Cys Gly Lys Ser Phe Thr Ser Asn Ser Tyr Leu 
305                 310                 315                 320


Ser Val His Lys Arg Ile His Asn Arg Trp Ile 
                325                 330


<210>  9080
<211>  701
<212>  DNA
<213>  Homo sapiens

<400>  9080
gaattcatac tggagaaaaa ccctatgact gtagtcaatt gttttcacgt tttccgcacc     60

agttgtaacc tcaaaagcca caagaggatt cacacggggg agaatcacca tgaatgtaat    120

cagtgtggaa aagctttcag cacaaggtcc tctctcactg ggcacaatag cattcataca    180

ggggagaaac cttatgaatg tcacgattgt gggaaaacct tcaggaagag ctcctatctg    240

acacagcacg taagaactca tactggagaa aaaccctatg aatgtaacga gtgtgggaaa    300

tccttcagca gtagcttttc tcttactgtg cacaagagaa tacataccgg agagaaaccc    360

tacgagtgca gtgactgtgg aaaagccttt aataatctct cagctgtgaa gaaacactta    420

agaactcaca ctggagaaaa accctatgaa tgtaatcatt gtgggaaatc cttcacaagt    480

aactcctatc tttctgtgca caagagaata cataatagat ggatatgaat tactgcagga    540

acttctggag gaaagcactc attgatcttt catccctaag atagtttgag agagctcaca    600

ctggatatat aagttatttg ttgcagcata acaaatgatc cccgcaaatt ttgtggcttc    660

aaacacgaaa tgtttattct ctaacaattt ctacagatca g                        701


<210>  9081
<211>  167
<212>  PRT
<213>  Homo sapiens

<400>  9081

Met Thr Val Val Asn Cys Phe His Val Phe Arg Thr Ser Cys Asn Leu 
1               5                   10                  15


Lys Ser His Lys Arg Ile His Thr Gly Glu Asn His His Glu Cys Asn 
            20                  25                  30


Gln Cys Gly Lys Ala Phe Ser Thr Arg Ser Ser Leu Thr Gly His Asn 
        35                  40                  45


Ser Ile His Thr Gly Glu Lys Pro Tyr Glu Cys His Asp Cys Gly Lys 
    50                  55                  60


Thr Phe Arg Lys Ser Ser Tyr Leu Thr Gln His Val Arg Thr His Thr 
65                  70                  75                  80


Gly Glu Lys Pro Tyr Glu Cys Asn Glu Cys Gly Lys Ser Phe Ser Ser 
                85                  90                  95


Ser Phe Ser Leu Thr Val His Lys Arg Ile His Thr Gly Glu Lys Pro 
            100                 105                 110


Tyr Glu Cys Ser Asp Cys Gly Lys Ala Phe Asn Asn Leu Ser Ala Val 
        115                 120                 125


Lys Lys His Leu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn 
    130                 135                 140


His Cys Gly Lys Ser Phe Thr Ser Asn Ser Tyr Leu Ser Val His Lys 
145                 150                 155                 160


Arg Ile His Asn Arg Trp Ile 
                165


<210>  9082
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  9082
caggtggccc tgaattcatt gcctgctcag caaaataaag gcccagtgtg gaagccggaa     60

cttgcatttg aagaaggatg ggaaggatgg gttgaggagg gcccatcccc agcagcccga    120

gagggaggag gccacggaga cttggagcat tcccgtttct tccagagcgc tgcgggataa    180

aggaggagcg tcctgcttcc cggctgccct gttgctgtcg gagtcacagg atggcggctg    240

tcatcctgcc ctcgactgct gctccgtctt ccctgttccc agcctctcag caaaaaggac    300

acacacaggg cggagagctg gttaatgagc tcctgacaag ctggctacgg ggcttggtaa    360

ccttcgagga tgtggccgtg gagttcaccc aggaggagtg ggcgttgctg gaccctgccc    420

aaaggacact gtacagggat gtgatgctgg agaactgcag gaacctggcc tcactagggt    480

gtcgtgttaa taaacccagt ctgatatccc agttggaaca agacaagaag gtggtgacag    540


<210>  9083
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  9083

Met Ala Ala Val Ile Leu Pro Ser Thr Ala Ala Pro Ser Ser Leu Phe 
1               5                   10                  15


Pro Ala Ser Gln Gln Lys Gly His Thr Gln Gly Gly Glu Leu Val Asn 
            20                  25                  30


Glu Leu Leu Thr Ser Trp Leu Arg Gly Leu Val Thr Phe Glu Asp Val 
        35                  40                  45


Ala Val Glu Phe Thr Gln Glu Glu Trp Ala Leu Leu Asp Pro Ala Gln 
    50                  55                  60


Arg Thr Leu Tyr Arg Asp Val Met Leu Glu Asn Cys Arg Asn Leu Ala 
65                  70                  75                  80


Ser Leu Gly Cys Arg Val Asn Lys Pro Ser Leu Ile Ser Gln Leu Glu 
                85                  90                  95


Gln Asp Lys Lys Val Val 
            100


<210>  9084
<211>  511
<212>  DNA
<213>  Homo sapiens

<400>  9084
cctcaatgct tgtctcctta ggccattccc aggtccagtg cacagtacca cagagcagct     60

gccttttctc actcagactg ggagctcctg tgatcttatt tccctcaatc tccaggggat    120

catgggcccg tgacatggca gaaagcagag aaatacttgc ccagcagaac tccagccagg    180

cgtgacttca atcatccacc tgctccaggg gacattcggg cagaccaccc tgtgcaaagg    240

ctgtgacgtt gccactctgg aataacacgg tcaccaacgt gtagagaacc ctcagcctgc    300

agggcgatcc cacaggtcag catggcttcc cactcgtcaa acctcctctc ctctctttaa    360

acttcacacc tcctcccctg tcccctctgt ggtaactgct tcctaacgag cccttgacga    420

tcccagcctc ccggtgctca caccctgtgt aggcccgacg cacacacgga attagagctg    480

acctgtgtga ccagcagaat atggctgagg a                                   511


<210>  9085
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  9085

Met Leu Val Ser Leu Gly His Ser Gln Val Gln Cys Thr Val Pro Gln 
1               5                   10                  15


Ser Ser Cys Leu Phe Ser Leu Arg Leu Gly Ala Pro Val Ile Leu Phe 
            20                  25                  30


Pro Ser Ile Ser Arg Gly Ser Trp Ala Arg Asp Met Ala Glu Ser Arg 
        35                  40                  45


Glu Ile Leu Ala Gln Gln Asn Ser Ser Gln Ala 
    50                  55


<210>  9086
<211>  292
<212>  DNA
<213>  Homo sapiens

<400>  9086
ggcgcttttg gccccgcggg aggggccggg ctcgatgaga aaagcatcat tcaagctcag     60

attcgtgttg aagcctgcca caaggtccac ctgttgttgt gggtttttgg gtgaccaggt    120

gagtacagtg tggaacctac aacaaggttt cagcaggctc tgctgtgtag aagaactcct    180

cgtgggcttt tcctgtgctg gggttgtaac cacattgaag tcactaagag tgaaggtatc    240

ttaaggaaag ttcaaggtaa aaagacagag gtgtttatgg ttacatgtgt gt            292


<210>  9087
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  9087

Met Arg Lys Ala Ser Phe Lys Leu Arg Phe Val Leu Lys Pro Ala Thr 
1               5                   10                  15


Arg Ser Thr Cys Cys Cys Gly Phe Leu Gly Asp Gln Val Ser Thr Val 
            20                  25                  30


Trp Asn Leu Gln Gln Gly Phe Ser Arg Leu Cys Cys Val Glu Glu Leu 
        35                  40                  45


Leu Val Gly Phe Ser Cys Ala Gly Val Val Thr Thr Leu Lys Ser Leu 
    50                  55                  60


Arg Val Lys Val Ser 
65


<210>  9088
<211>  748
<212>  DNA
<213>  Homo sapiens

<400>  9088
tccttgtcct gagaaggcag gcttcattga tcaatttgac cccatttcat gatttatttt     60

aatagtgtaa gaggaaaaga agtgtgatgg ccaagagttc acagaggaag caacgtgact    120

gtgtaaacca atgcaaatca aagcctggct tgagcacctc aatccctttg agaatgtcca    180

gttacacatt caagaggcca gtaacgagaa ttacacccca tcctggcaat gaggtcagat    240

accatcaatg ggaggagagc ttggagaagc ctcagcaggt ctgctggcag aggagactgc    300

agggactcca ggcttacagc agtgcaggag aactttcaag cactttggat cttgccaata    360

ccttgcaaaa acttgtccct agttacacag gtggatctct gctggaggat cttgccagtg    420

gtctggagca ctcctgcccc atgccccacc ttgcctgctc ttcagatgcg gtggagataa    480

ttcctgcaga gggagtgggt atctcgcagc tcctctgcaa acaatttctg gttactgagg    540

aagatatcag gaaacaggaa gggaaagtga agacagtcag agagagactc gcaatagcac    600

tgattgcgga tggactcgct aatgaggcag agaaagtgag agaccaagaa ggccgtcctg    660

aaaaacgcta agaaaaaaag ggaagatagt gcagatgaaa taaagtgtaa tcctttatta    720

acatctcttt gcagtgtccc caatgagg                                       748


<210>  9089
<211>  194
<212>  PRT
<213>  Homo sapiens

<400>  9089

Met Ala Lys Ser Ser Gln Arg Lys Gln Arg Asp Cys Val Asn Gln Cys 
1               5                   10                  15


Lys Ser Lys Pro Gly Leu Ser Thr Ser Ile Pro Leu Arg Met Ser Ser 
            20                  25                  30


Tyr Thr Phe Lys Arg Pro Val Thr Arg Ile Thr Pro His Pro Gly Asn 
        35                  40                  45


Glu Val Arg Tyr His Gln Trp Glu Glu Ser Leu Glu Lys Pro Gln Gln 
    50                  55                  60


Val Cys Trp Gln Arg Arg Leu Gln Gly Leu Gln Ala Tyr Ser Ser Ala 
65                  70                  75                  80


Gly Glu Leu Ser Ser Thr Leu Asp Leu Ala Asn Thr Leu Gln Lys Leu 
                85                  90                  95


Val Pro Ser Tyr Thr Gly Gly Ser Leu Leu Glu Asp Leu Ala Ser Gly 
            100                 105                 110


Leu Glu His Ser Cys Pro Met Pro His Leu Ala Cys Ser Ser Asp Ala 
        115                 120                 125


Val Glu Ile Ile Pro Ala Glu Gly Val Gly Ile Ser Gln Leu Leu Cys 
    130                 135                 140


Lys Gln Phe Leu Val Thr Glu Glu Asp Ile Arg Lys Gln Glu Gly Lys 
145                 150                 155                 160


Val Lys Thr Val Arg Glu Arg Leu Ala Ile Ala Leu Ile Ala Asp Gly 
                165                 170                 175


Leu Ala Asn Glu Ala Glu Lys Val Arg Asp Gln Glu Gly Arg Pro Glu 
            180                 185                 190


Lys Arg 



<210>  9090
<211>  4100
<212>  DNA
<213>  Homo sapiens

<400>  9090
tcccaccttc actatagcca ccggccctct cctggtgcca ttcacactca acttcaccat     60

cactaaccta cagtatgagg agaacatggg tcaccctggc tccaggaagt tcaacatcac    120

ggagagtgtt ctgcagggtc tgctcaagcc cttgttcaag agcaccagtg ttggccctct    180

gtattctggc tgcagactga ccttgctcag gcctgagaag gatggagtag ccaccagagt    240

ggacgccatc tgcacccacc gccctgaccc caaaatccct gggctagaca gacagcagct    300

atactgggag ctgagccagc tgacccacag catcactgag ctgggaccct acaccctgga    360

tagggacagt ctctatgtca atggtttcac ccagcggagc tctgtgccca ccaccagcac    420

tcctgggact ttcacagtac agccggaaac ctctgagact ccatcatccc tccctggccc    480

cacagccact ggccctgtcc tgctgccatt caccctcaat tttaccatca ctaacctgca    540

gtatgaggag gacatgcgtc gccctggctc caggaagttc aacaccacgg agagggtcct    600

tcagggtctg cttatgccct tgttcaagaa caccagtgtc agctctctgt actctggttg    660

cagactgacc ttgctcaggc ctgagaagga tggggcagcc accagagtgg atgctgtctg    720

cacccatcgt cctgacccca aaagccctgg actggacaga gagcggctgt actggaagct    780

gagccagctg acccacggca tcactgagct gggcccctac accctggaca ggcacagtct    840

ctatgtcaat ggtttcaccc atcagagctc tatgacgacc accagaactc ctgatacctc    900

cacaatgcac ctggcaacct cgagaactcc agcctccctg tctggaccca tgaccgccag    960

ccctctcctg gtgctattca caattaactt caccatcact aacctgcggt atgaggagaa   1020

catgcatcac cctggctcta gaaagtttaa caccacggag agagtccttc agggtctgct   1080

caggcctgtg ttcaagaaca ccagtgttgg ccctctgtac tctggctgca gactgacctt   1140

gctcaggccc aagaaggatg gggcagccac caaagtggat gccatctgca cctaccgccc   1200

tgatcccaaa agccctggac tggacagaga gcagctatac tgggagctga gccagctgac   1260

ccacagcatc actgagctgg gcccctacac cctggacagg gacagtctct atgtcaatgg   1320

tttcacacag cggagctctg tgcccaccac tagcattcct gggaccccca cagtggacct   1380

gggaacatct gggactccag tttctaaacc tggtccctcg gctgccagcc ctctcctggt   1440

gctattcact ctcaacttca ccatcaccaa cctgcggtat gaggagaaca tgcagcaccc   1500

tggctccagg aagttcaaca ccacggagag ggtccttcag ggcctgctca ggtccctgtt   1560

caagagcacc agtgttggcc ctctgtactc tggctgcaga ctgactttgc tcaggcctga   1620

aaaggatggg acagccactg gagtggatgc catctgcacc caccaccctg accccaaaag   1680

ccctaggctg gacagagagc agctgtattg ggagctgagc cagctgaccc acaatatcac   1740

tgagctgggc ccctatgccc tggacaacga cagcctcttt gtcaatggtt tcactcatcg   1800

gagctctgtg tccaccacca gcactcctgg gacccccaca gtgtatctgg gagcatctaa   1860

gactccagcc tcgatatttg gcccttcagc tgccagccat ctcctgatac tattcaccct   1920

caacttcacc atcactaacc tgcggtatga ggagaacatg tggcctggct ccaggaagtt   1980

caacactaca gagagggtcc ttcagggcct gctaaggccc ttgttcaaga acaccagtgt   2040

tggccctctg tactctggct gcaggctgac cttgctcagg ccagagaaag atggggaagc   2100

caccggagtg gatgccatct gcacccaccg ccctgacccc acaggccctg ggctggacag   2160

agagcagctg tatttggagc tgagccagct gacccacagc atcactgagc tgggccccta   2220

cacactggac agggacagtc tctatgtcaa tggtttcacc catcggagct ctgtacccac   2280

caccagcacc ggggtggtca gcgaggagcc attcacactg aacttcacca tcaacaacct   2340

gcgctacatg gcggacatgg gccaacccgg ctccctcaag ttcaacatca cagacaacgt   2400

catgcagcac ctgctcagtc ctttgttcca gaggagcagc ctgggtgcac ggtacacagg   2460

ctgcagggtc atcgcactaa ggtctgtgaa gaacggtgct gagacacggg tggacctcct   2520

ctgcacctac ctgcagcccc tcagcggccc aggtctgcct atcaagcagg tgttccatga   2580

gctgagccag cagacccatg gcatcacccg gctgggcccc tactctctgg acaaagacag   2640

cctctacctt aacggttaca atgaacctgg tccagatgag cctcctacaa ccatggggta   2700

ccacctgaag accctcacac tcaacttcac catctccaat ctccagtatt caccagatat   2760

gggcaagggc tcagctacat tcaactccac cgagggggtc cttcagcacc tgctcagacc   2820

cttgttccag aagagcagca tgggcccctt ctacttgggt tgccaactga tctccctcag   2880

gcctgagaag gatggggcag ccactggtgt ggacaccacc tgcacctacc accctgaccc   2940

tgtgggcccc gggctggaca tacagcagct ttactgggag ctgagtcagc tgacccatgg   3000

tgtcacccaa ctgggcttct atgtcctgga cagggatagc ctcttcatca atggctatgc   3060

accccagaat ttatcaatcc ggggcgagta ccagataaat ttccacattg tcaactggaa   3120

cctcagtaat ccagacccca catcctcaga gtacatcacc ctgctgaggg acatccagga   3180

caaggtcacc acactctaca aaggcagtca actacatgac acattccgct tctgcctggt   3240

caccaacttg acgatggact ccgtgttggt cactgtcaag gcattgttct cctccaattt   3300

ggaccccagc ctggtggagc aagtctttct agataagacc ctgaatgcct cattccattg   3360

gctgggctcc acctaccagt tggtggacat ccatgtgaca gaaatggagt catcagttta   3420

tcaaccaaca agcagctcca gcacccagca cttctacctg aatttcacca tcaccaacct   3480

accatattcc caggacaaag cccagccagg caccaccaat taccagagga acaaaaggaa   3540

tattgaggat gcgctcaacc aactcttccg aaacagcagc atcaagagtt atttttctga   3600

ctgtcaagtt tcaacattca ggtctgtccc caacaggcac cacaccgggg tggactccct   3660

gtgtaacttc tcgccactgg ctcggagagt agacagagtt gccatctatg aggaatttct   3720

gcggatgacc cggaatggta cccagctgca gaacttcacc ctggacagga gcagtgtcct   3780

tgtggatggg tattctccca acagaaatga gcccttaact gggaattctg accttccctt   3840

ctgggctgtc atcctcatcg gcttggcagg actcctggga gtcatcacat gcctgatctg   3900

cggtgtcctg gtgaccaccc gccggcggaa gaaggaagga gaatacaacg tccagcaaca   3960

gtgcccaggc tactaccagt cacacctaga cctggaggat ctgcaatgac tggaacttgc   4020

cggtgcctgg ggtgcctttc ccccagccag ggtccaaaga agcttggctg gggcagaaat   4080

aaaccatatt ggtcggacac                                               4100


<210>  9091
<211>  1307
<212>  PRT
<213>  Homo sapiens

<400>  9091

Met Gly His Pro Gly Ser Arg Lys Phe Asn Ile Thr Glu Ser Val Leu 
1               5                   10                  15


Gln Gly Leu Leu Lys Pro Leu Phe Lys Ser Thr Ser Val Gly Pro Leu 
            20                  25                  30


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Val 
        35                  40                  45


Ala Thr Arg Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Lys Ile 
    50                  55                  60


Pro Gly Leu Asp Arg Gln Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr 
65                  70                  75                  80


His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu 
                85                  90                  95


Tyr Val Asn Gly Phe Thr Gln Arg Ser Ser Val Pro Thr Thr Ser Thr 
            100                 105                 110


Pro Gly Thr Phe Thr Val Gln Pro Glu Thr Ser Glu Thr Pro Ser Ser 
        115                 120                 125


Leu Pro Gly Pro Thr Ala Thr Gly Pro Val Leu Leu Pro Phe Thr Leu 
    130                 135                 140


Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met Arg Arg Pro 
145                 150                 155                 160


Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu 
                165                 170                 175


Met Pro Leu Phe Lys Asn Thr Ser Val Ser Ser Leu Tyr Ser Gly Cys 
            180                 185                 190


Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Ala Ala Thr Arg Val 
        195                 200                 205


Asp Ala Val Cys Thr His Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp 
    210                 215                 220


Arg Glu Arg Leu Tyr Trp Lys Leu Ser Gln Leu Thr His Gly Ile Thr 
225                 230                 235                 240


Glu Leu Gly Pro Tyr Thr Leu Asp Arg His Ser Leu Tyr Val Asn Gly 
                245                 250                 255


Phe Thr His Gln Ser Ser Met Thr Thr Thr Arg Thr Pro Asp Thr Ser 
            260                 265                 270


Thr Met His Leu Ala Thr Ser Arg Thr Pro Ala Ser Leu Ser Gly Pro 
        275                 280                 285


Met Thr Ala Ser Pro Leu Leu Val Leu Phe Thr Ile Asn Phe Thr Ile 
    290                 295                 300


Thr Asn Leu Arg Tyr Glu Glu Asn Met His His Pro Gly Ser Arg Lys 
305                 310                 315                 320


Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Arg Pro Val Phe 
                325                 330                 335


Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu 
            340                 345                 350


Leu Arg Pro Lys Lys Asp Gly Ala Ala Thr Lys Val Asp Ala Ile Cys 
        355                 360                 365


Thr Tyr Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp Arg Glu Gln Leu 
    370                 375                 380


Tyr Trp Glu Leu Ser Gln Leu Thr His Ser Ile Thr Glu Leu Gly Pro 
385                 390                 395                 400


Tyr Thr Leu Asp Arg Asp Ser Leu Tyr Val Asn Gly Phe Thr Gln Arg 
                405                 410                 415


Ser Ser Val Pro Thr Thr Ser Ile Pro Gly Thr Pro Thr Val Asp Leu 
            420                 425                 430


Gly Thr Ser Gly Thr Pro Val Ser Lys Pro Gly Pro Ser Ala Ala Ser 
        435                 440                 445


Pro Leu Leu Val Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Arg 
    450                 455                 460


Tyr Glu Glu Asn Met Gln His Pro Gly Ser Arg Lys Phe Asn Thr Thr 
465                 470                 475                 480


Glu Arg Val Leu Gln Gly Leu Leu Arg Ser Leu Phe Lys Ser Thr Ser 
                485                 490                 495


Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu 
            500                 505                 510


Lys Asp Gly Thr Ala Thr Gly Val Asp Ala Ile Cys Thr His His Pro 
        515                 520                 525


Asp Pro Lys Ser Pro Arg Leu Asp Arg Glu Gln Leu Tyr Trp Glu Leu 
    530                 535                 540


Ser Gln Leu Thr His Asn Ile Thr Glu Leu Gly Pro Tyr Ala Leu Asp 
545                 550                 555                 560


Asn Asp Ser Leu Phe Val Asn Gly Phe Thr His Arg Ser Ser Val Ser 
                565                 570                 575


Thr Thr Ser Thr Pro Gly Thr Pro Thr Val Tyr Leu Gly Ala Ser Lys 
            580                 585                 590


Thr Pro Ala Ser Ile Phe Gly Pro Ser Ala Ala Ser His Leu Leu Ile 
        595                 600                 605


Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Arg Tyr Glu Glu Asn 
    610                 615                 620


Met Trp Pro Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln 
625                 630                 635                 640


Gly Leu Leu Arg Pro Leu Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr 
                645                 650                 655


Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Glu Ala 
            660                 665                 670


Thr Gly Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Thr Gly Pro 
        675                 680                 685


Gly Leu Asp Arg Glu Gln Leu Tyr Leu Glu Leu Ser Gln Leu Thr His 
    690                 695                 700


Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu Tyr 
705                 710                 715                 720


Val Asn Gly Phe Thr His Arg Ser Ser Val Pro Thr Thr Ser Thr Gly 
                725                 730                 735


Val Val Ser Glu Glu Pro Phe Thr Leu Asn Phe Thr Ile Asn Asn Leu 
            740                 745                 750


Arg Tyr Met Ala Asp Met Gly Gln Pro Gly Ser Leu Lys Phe Asn Ile 
        755                 760                 765


Thr Asp Asn Val Met Gln His Leu Leu Ser Pro Leu Phe Gln Arg Ser 
    770                 775                 780


Ser Leu Gly Ala Arg Tyr Thr Gly Cys Arg Val Ile Ala Leu Arg Ser 
785                 790                 795                 800


Val Lys Asn Gly Ala Glu Thr Arg Val Asp Leu Leu Cys Thr Tyr Leu 
                805                 810                 815


Gln Pro Leu Ser Gly Pro Gly Leu Pro Ile Lys Gln Val Phe His Glu 
            820                 825                 830


Leu Ser Gln Gln Thr His Gly Ile Thr Arg Leu Gly Pro Tyr Ser Leu 
        835                 840                 845


Asp Lys Asp Ser Leu Tyr Leu Asn Gly Tyr Asn Glu Pro Gly Pro Asp 
    850                 855                 860


Glu Pro Pro Thr Thr Met Gly Tyr His Leu Lys Thr Leu Thr Leu Asn 
865                 870                 875                 880


Phe Thr Ile Ser Asn Leu Gln Tyr Ser Pro Asp Met Gly Lys Gly Ser 
                885                 890                 895


Ala Thr Phe Asn Ser Thr Glu Gly Val Leu Gln His Leu Leu Arg Pro 
            900                 905                 910


Leu Phe Gln Lys Ser Ser Met Gly Pro Phe Tyr Leu Gly Cys Gln Leu 
        915                 920                 925


Ile Ser Leu Arg Pro Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Thr 
    930                 935                 940


Thr Cys Thr Tyr His Pro Asp Pro Val Gly Pro Gly Leu Asp Ile Gln 
945                 950                 955                 960


Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr His Gly Val Thr Gln Leu 
                965                 970                 975


Gly Phe Tyr Val Leu Asp Arg Asp Ser Leu Phe Ile Asn Gly Tyr Ala 
            980                 985                 990


Pro Gln Asn Leu Ser Ile Arg Gly Glu Tyr Gln Ile Asn Phe His Ile 
        995                 1000                1005


Val Asn Trp Asn Leu Ser Asn Pro Asp Pro Thr Ser Ser Glu Tyr Ile 
    1010                1015                1020


Thr Leu Leu Arg Asp Ile Gln Asp Lys Val Thr Thr Leu Tyr Lys Gly 
1025                1030                1035                1040


Ser Gln Leu His Asp Thr Phe Arg Phe Cys Leu Val Thr Asn Leu Thr 
                1045                1050                1055


Met Asp Ser Val Leu Val Thr Val Lys Ala Leu Phe Ser Ser Asn Leu 
            1060                1065                1070


Asp Pro Ser Leu Val Glu Gln Val Phe Leu Asp Lys Thr Leu Asn Ala 
        1075                1080                1085


Ser Phe His Trp Leu Gly Ser Thr Tyr Gln Leu Val Asp Ile His Val 
    1090                1095                1100


Thr Glu Met Glu Ser Ser Val Tyr Gln Pro Thr Ser Ser Ser Ser Thr 
1105                1110                1115                1120


Gln His Phe Tyr Leu Asn Phe Thr Ile Thr Asn Leu Pro Tyr Ser Gln 
                1125                1130                1135


Asp Lys Ala Gln Pro Gly Thr Thr Asn Tyr Gln Arg Asn Lys Arg Asn 
            1140                1145                1150


Ile Glu Asp Ala Leu Asn Gln Leu Phe Arg Asn Ser Ser Ile Lys Ser 
        1155                1160                1165


Tyr Phe Ser Asp Cys Gln Val Ser Thr Phe Arg Ser Val Pro Asn Arg 
    1170                1175                1180


His His Thr Gly Val Asp Ser Leu Cys Asn Phe Ser Pro Leu Ala Arg 
1185                1190                1195                1200


Arg Val Asp Arg Val Ala Ile Tyr Glu Glu Phe Leu Arg Met Thr Arg 
                1205                1210                1215


Asn Gly Thr Gln Leu Gln Asn Phe Thr Leu Asp Arg Ser Ser Val Leu 
            1220                1225                1230


Val Asp Gly Tyr Ser Pro Asn Arg Asn Glu Pro Leu Thr Gly Asn Ser 
        1235                1240                1245


Asp Leu Pro Phe Trp Ala Val Ile Leu Ile Gly Leu Ala Gly Leu Leu 
    1250                1255                1260


Gly Val Ile Thr Cys Leu Ile Cys Gly Val Leu Val Thr Thr Arg Arg 
1265                1270                1275                1280


Arg Lys Lys Glu Gly Glu Tyr Asn Val Gln Gln Gln Cys Pro Gly Tyr 
                1285                1290                1295


Tyr Gln Ser His Leu Asp Leu Glu Asp Leu Gln 
            1300                1305


<210>  9092
<211>  3570
<212>  DNA
<213>  Homo sapiens

<400>  9092
tcccaccttc actatagcca ccggccctct cctggtgcca ttcacactca acttcaccat     60

cactaaccta cagtatgagg agaacatggg tcaccctggc tccaggaagt tcaacatcac    120

ggagagtgtt ctgcagggtc tgctcaagcc cttgttcaag agcaccagtg ttggccctct    180

gtattctggc tgcagactga ccttgctcag gcctgagaag gatggagtag ccaccagagt    240

ggacgccatc tgcacccacc gccctgaccc caaaatccct gggctagaca gacagcagct    300

atactgggag ctgagccagc tgacccacag catcactgag ctgggaccct acaccctgga    360

tagggacagt ctctatgtca atggtttcac ccagcggagc tctgtgccca ccaccagcac    420

tcctgggact ttcacagtac agccggaaac ctctgagact ccatcatccc tccctggccc    480

cacagccact ggccctgtcc tgctgccatt caccctcaat tttaccatca ctaacctgca    540

gtatgaggag gacatgcgtc gccctggctc caggaagttc aacaccacgg agagggtcct    600

tcagggtctg cttatgccct tgttcaagaa caccagtgtc agctctctgt actctggttg    660

cagactgacc ttgctcaggc ctgagaagga tggggcagcc accagagtgg atgctgtctg    720

cacccatcgt cctgacccca aaagccctgg actggacaga gagcggctgt actggaagct    780

gagccagctg acccacggca tcactgagct gggcccctac accctggaca ggcacagtct    840

ctatgtcaat ggtttcaccc atcagagctc tatgacgacc accagaactc ctgatacctc    900

cacaatgcac ctggcaacct cgagaactcc agcctccctg tctggaccca tgaccgccag    960

ccctctcctg gtgctattca caattaactt caccatcact aacctgcggt atgaggagaa   1020

catgcatcac cctggctcta gaaagtttaa caccacggag agagtccttc agggtctgct   1080

caggcctgtg ttcaagaaca ccagtgttgg ccctctgtac tctggctgca gactgacctt   1140

gctcaggccc aagaaggatg gggcagccac caaagtggat gccatctgca cctaccgccc   1200

tgatcccaaa agccctggac tggacagaga gcagctatac tgggagctga gccagctgac   1260

ccacagcatc actgagctgg gcccctacac cctggacagg gacagtctct atgtcaatgg   1320

tttcacacag cggagctctg tgcccaccac tagcattcct gggaccccca cagtggacct   1380

gggaacatct gggactccag tttctaaacc tggtccctcg gctgccagcc ctctcctggt   1440

gctattcact ctcaacttca ccatcaccaa cctgcggtat gaggagaaca tgcagcaccc   1500

tggctccagg aagttcaaca ccacggagag ggtccttcag ggcctgctca ggtccctgtt   1560

caagagcacc agtgttggcc ctctgtactc tggctgcaga ctgactttgc tcaggcctga   1620

aaaggatggg acagccactg gagtggatgc catctgcacc caccaccctg accccaaaag   1680

ccctaggctg gacagagagc agctgtattg ggagctgagc cagctgaccc acaatatcac   1740

tgagctgggc ccctatgccc tggacaacga cagcctcttt gtcaatggtt tcactcatcg   1800

gagctctgtg tccaccacca gcactcctgg gacccccaca gtgtatctgg gagcatctaa   1860

gactccagcc tcgatatttg gcccttcagc tgccagccat ctcctgatac tattcaccct   1920

caacttcacc atcactaacc tgcggtatga ggagaacatg tggcctggct ccaggaagtt   1980

caacactaca gagagggtcc ttcagggcct gctaaggccc ttgttcaaga acaccagtgt   2040

tggccctctg tactctggct gcaggctgac cttgctcagg ccagagaaag atggggaagc   2100

caccggagtg gatgccatct gcacccaccg ccctgacccc acaggccctg ggctggacag   2160

agagcagctg tatttggagc tgagccagct gacccacagc atcactgagc tgggccccta   2220

cacactggac agggacagtc tctatgtcaa tggtttcacc catcggagct ctgtacccac   2280

caccagcacc ggggtggtca gcgaggagcc attcacactg aacttcacca tcaacaacct   2340

gcgctacatg gcggacatgg gccaacccgg ctccctcaag ttcaacatca cagacaacgt   2400

catgcagcac ctgctcagtc ctttgttcca gaggagcagc ctgggtgcac ggtacacagg   2460

ctgcagggtc atcgcactaa ggtctgtgaa gaacggtgct gagacacggg tggacctcct   2520

ctgcacctac ctgcagcccc tcagcggccc aggtctgcct atcaagcagg tgttccatga   2580

gctgagccag cagacccatg gcatcacccg gctgggcccc tactctctgg acaaagacag   2640

cctctacctt aacggtcacc acactctaca aaggcagtca actacatgac acattccgct   2700

tctgcctggt caccaacttg acgatggact ccgtgttggt cactgtcaag gcattgttct   2760

cctccaattt ggaccccagc ctggtggagc aagtctttct agataagacc ctgaatgcct   2820

cattccattg gctgggctcc acctaccagt tggtggacat ccatgtgaca gaaatggagt   2880

catcagttta tcaaccaaca agcagctcca gcacccagca cttctacctg aatttcacca   2940

tcaccaacct accatattcc caggacaaag cccagccagg caccaccaat taccagagga   3000

acaaaaggaa tattgaggat gcgctcaacc aactcttccg aaacagcagc atcaagagtt   3060

atttttctga ctgtcaagtt tcaacattca ggtctgtccc caacaggcac cacaccgggg   3120

tggactccct gtgtaacttc tcgccactgg ctcggagagt agacagagtt gccatctatg   3180

aggaatttct gcggatgacc cggaatggta cccagctgca gaacttcacc ctggacagga   3240

gcagtgtcct tgtggatggg tattctccca acagaaatga gcccttaact gggaattctg   3300

accttccctt ctgggctgtc atcctcatcg gcttggcagg actcctggga gtcatcacat   3360

gcctgatctg cggtgtcctg gtgaccaccc gccggcggaa gaaggaagga gaatacaacg   3420

tccagcaaca gtgcccaggc tactaccagt cacacctaga cctggaggat ctgcaatgac   3480

tggaacttgc cggtgcctgg ggtgcctttc ccccagccag ggtccaaaga agcttggctg   3540

gggcagaaat aaaccatatt ggtcggacac                                    3570


<210>  9093
<211>  867
<212>  PRT
<213>  Homo sapiens

<400>  9093

Met Gly His Pro Gly Ser Arg Lys Phe Asn Ile Thr Glu Ser Val Leu 
1               5                   10                  15


Gln Gly Leu Leu Lys Pro Leu Phe Lys Ser Thr Ser Val Gly Pro Leu 
            20                  25                  30


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Val 
        35                  40                  45


Ala Thr Arg Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Lys Ile 
    50                  55                  60


Pro Gly Leu Asp Arg Gln Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr 
65                  70                  75                  80


His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu 
                85                  90                  95


Tyr Val Asn Gly Phe Thr Gln Arg Ser Ser Val Pro Thr Thr Ser Thr 
            100                 105                 110


Pro Gly Thr Phe Thr Val Gln Pro Glu Thr Ser Glu Thr Pro Ser Ser 
        115                 120                 125


Leu Pro Gly Pro Thr Ala Thr Gly Pro Val Leu Leu Pro Phe Thr Leu 
    130                 135                 140


Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met Arg Arg Pro 
145                 150                 155                 160


Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu 
                165                 170                 175


Met Pro Leu Phe Lys Asn Thr Ser Val Ser Ser Leu Tyr Ser Gly Cys 
            180                 185                 190


Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Ala Ala Thr Arg Val 
        195                 200                 205


Asp Ala Val Cys Thr His Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp 
    210                 215                 220


Arg Glu Arg Leu Tyr Trp Lys Leu Ser Gln Leu Thr His Gly Ile Thr 
225                 230                 235                 240


Glu Leu Gly Pro Tyr Thr Leu Asp Arg His Ser Leu Tyr Val Asn Gly 
                245                 250                 255


Phe Thr His Gln Ser Ser Met Thr Thr Thr Arg Thr Pro Asp Thr Ser 
            260                 265                 270


Thr Met His Leu Ala Thr Ser Arg Thr Pro Ala Ser Leu Ser Gly Pro 
        275                 280                 285


Met Thr Ala Ser Pro Leu Leu Val Leu Phe Thr Ile Asn Phe Thr Ile 
    290                 295                 300


Thr Asn Leu Arg Tyr Glu Glu Asn Met His His Pro Gly Ser Arg Lys 
305                 310                 315                 320


Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Arg Pro Val Phe 
                325                 330                 335


Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu 
            340                 345                 350


Leu Arg Pro Lys Lys Asp Gly Ala Ala Thr Lys Val Asp Ala Ile Cys 
        355                 360                 365


Thr Tyr Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp Arg Glu Gln Leu 
    370                 375                 380


Tyr Trp Glu Leu Ser Gln Leu Thr His Ser Ile Thr Glu Leu Gly Pro 
385                 390                 395                 400


Tyr Thr Leu Asp Arg Asp Ser Leu Tyr Val Asn Gly Phe Thr Gln Arg 
                405                 410                 415


Ser Ser Val Pro Thr Thr Ser Ile Pro Gly Thr Pro Thr Val Asp Leu 
            420                 425                 430


Gly Thr Ser Gly Thr Pro Val Ser Lys Pro Gly Pro Ser Ala Ala Ser 
        435                 440                 445


Pro Leu Leu Val Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Arg 
    450                 455                 460


Tyr Glu Glu Asn Met Gln His Pro Gly Ser Arg Lys Phe Asn Thr Thr 
465                 470                 475                 480


Glu Arg Val Leu Gln Gly Leu Leu Arg Ser Leu Phe Lys Ser Thr Ser 
                485                 490                 495


Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu 
            500                 505                 510


Lys Asp Gly Thr Ala Thr Gly Val Asp Ala Ile Cys Thr His His Pro 
        515                 520                 525


Asp Pro Lys Ser Pro Arg Leu Asp Arg Glu Gln Leu Tyr Trp Glu Leu 
    530                 535                 540


Ser Gln Leu Thr His Asn Ile Thr Glu Leu Gly Pro Tyr Ala Leu Asp 
545                 550                 555                 560


Asn Asp Ser Leu Phe Val Asn Gly Phe Thr His Arg Ser Ser Val Ser 
                565                 570                 575


Thr Thr Ser Thr Pro Gly Thr Pro Thr Val Tyr Leu Gly Ala Ser Lys 
            580                 585                 590


Thr Pro Ala Ser Ile Phe Gly Pro Ser Ala Ala Ser His Leu Leu Ile 
        595                 600                 605


Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Arg Tyr Glu Glu Asn 
    610                 615                 620


Met Trp Pro Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln 
625                 630                 635                 640


Gly Leu Leu Arg Pro Leu Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr 
                645                 650                 655


Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Glu Ala 
            660                 665                 670


Thr Gly Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Thr Gly Pro 
        675                 680                 685


Gly Leu Asp Arg Glu Gln Leu Tyr Leu Glu Leu Ser Gln Leu Thr His 
    690                 695                 700


Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu Tyr 
705                 710                 715                 720


Val Asn Gly Phe Thr His Arg Ser Ser Val Pro Thr Thr Ser Thr Gly 
                725                 730                 735


Val Val Ser Glu Glu Pro Phe Thr Leu Asn Phe Thr Ile Asn Asn Leu 
            740                 745                 750


Arg Tyr Met Ala Asp Met Gly Gln Pro Gly Ser Leu Lys Phe Asn Ile 
        755                 760                 765


Thr Asp Asn Val Met Gln His Leu Leu Ser Pro Leu Phe Gln Arg Ser 
    770                 775                 780


Ser Leu Gly Ala Arg Tyr Thr Gly Cys Arg Val Ile Ala Leu Arg Ser 
785                 790                 795                 800


Val Lys Asn Gly Ala Glu Thr Arg Val Asp Leu Leu Cys Thr Tyr Leu 
                805                 810                 815


Gln Pro Leu Ser Gly Pro Gly Leu Pro Ile Lys Gln Val Phe His Glu 
            820                 825                 830


Leu Ser Gln Gln Thr His Gly Ile Thr Arg Leu Gly Pro Tyr Ser Leu 
        835                 840                 845


Asp Lys Asp Ser Leu Tyr Leu Asn Gly His His Thr Leu Gln Arg Gln 
    850                 855                 860


Ser Thr Thr 
865


<210>  9094
<211>  5239
<212>  DNA
<213>  Homo sapiens

<400>  9094
cccatgttca agaacaccag tgttggccct ctgtactctg gctgcagact gaccttgctc     60

aggtccgaga aggatggagc agccactgga gtggatgcca tctgcaccca ccgtcttgac    120

cccaaaagcc ctggagtgga cagggagcag ctatactggg agctgagcca gctgaccaat    180

ggcatcaaag agctgggtcc ctacaccctg gacagaaaca gtctctatgt caatggtcct    240

gggacctcca cagtggacct tgggacctca gggactccat cctccctccc cagccctaca    300

tctgctggcc ctctcctggt gccattcacc ctcaacttca ccatcaccaa cctgcagtac    360

gaggaggaca tgcatcaccc aggctccagg aagttcaaca ccacggagcg ggtcctgcag    420

ggtctgcttg gtcccatgtt caagaacacc agtgtcggcc ttctgtactc tggctgcaga    480

ctgaccttgc tcaggcctga gaagaatggg gcagccactg gaatggatgc catctgcagc    540

caccgtcttg accccaaaag ccctggactc aacagagagc agctgtactg ggagctgagc    600

cagctgaccc atggcatcaa agagctgggc ccctacaccc tggacaggaa cagtctctat    660

gtcaatggtt tcacccatcg gagctctgtg gcccccacca gcactcctgg gacctccaca    720

gtggaccttg ggacctcagg gactccatcc tccctcccca gccccacaac agctgttcct    780

ctcctggtgc cgttcaccct caactttacc atcaccaatc tgcagtatgg ggaggacatg    840

cgtcaccctg gctccaggaa gttcaacacc acagagaggg tcctgcaggg tctgcttggt    900

cccttgttca agaactccag tgtcggccct ctgtactctg gctgcagact gatctctctc    960

aggtctgaga aggatggggc agccactgga gtggatgcca tctgcaccca ccaccttaac   1020

cctcaaagcc ctggactgga cagggagcag ctgtactggc agctgagcca gatgaccaat   1080

ggcatcaaag agctgggccc ctacaccctg gaccggaaca gtctctacgt caatggtttc   1140

acccatcgga gctctgggct caccaccagc accaccggcc ctctcctggt gccattcaca   1200

ctcaacttca ccatcactaa cctacagtat gaggagaaca tgggtcaccc tggctccagg   1260

aagttcaaca tcacggagag tgttctgcag ggtctgctca agcccttgtt caagagcacc   1320

agtgttggcc ctctgtattc tggctgcaga ctgaccttgc tcaggcctga gaaggatgga   1380

gtagccacca gagtggacgc catctgcacc caccgccctg accccaaaat ccctgggcta   1440

gacagacagc agctatactg ggagctgagc cagctgaccc acagcatcac tgagctggga   1500

ccctacaccc tggataggga cagtctctat gtcaatggtt tcacccagcg gagctctgtg   1560

cccaccacca gcactcctgg gactttcaca gtacagccgg aaacctctga gactccatca   1620

tccctccctg gccccacagc cactggccct gtcctgctgc cattcaccct caattttacc   1680

atcactaacc tgcagtatga ggaggacatg cgtcgccctg gctccaggaa gttcaacacc   1740

acggagaggg tccttcaggg tctgcttatg cccttgttca agaacaccag tgtcagctct   1800

ctgtactctg gttgcagact gaccttgctc aggcctgaga aggatggggc agccaccaga   1860

gtggatgctg tctgcaccca tcgtcctgac cccaaaagcc ctggactgga cagagagcgg   1920

ctgtactgga agctgagcca gctgacccac ggcatcactg agctgggccc ctacaccctg   1980

gacaggcaca gtctctatgt caatggtttc acccatcaga gctctatgac gaccaccaga   2040

actcctgata cctccacaat gcacctggca acctcgagaa ctccagcctc cctgtctgga   2100

cccatgaccg ccagccctct cctggtgcta ttcacaatta acttcaccat cactaacctg   2160

cggtatgagg agaacatgca tcaccctggc tctagaaagt ttaacaccac ggagagagtc   2220

cttcagggtc tgctcaggcc tgtgttcaag aacaccagtg ttggccctct gtactctggc   2280

tgcagactga ccttgctcag gcccaagaag gatggggcag ccaccaaagt ggatgccatc   2340

tgcacctacc gccctgatcc caaaagccct ggactggaca gagagcagct atactgggag   2400

ctgagccagc tgacccacag catcactgag ctgggcccct acaccctgga cagggacagt   2460

ctctatgtca atggtttcac acagcggagc tctgtgccca ccactagcat tcctgggacc   2520

cccacagtgg acctgggaac atctgggact ccagtttcta aacctggtcc ctcggctgcc   2580

agccctctcc tggtgctatt cactctcaac ttcaccatca ccaacctgcg gtatgaggag   2640

aacatgcagc accctggctc caggaagttc aacaccacgg agagggtcct tcagggcctg   2700

ctcaggtccc tgttcaagag caccagtgtt ggccctctgt actctggctg cagactgact   2760

ttgctcaggc ctgaaaagga tgggacagcc actggagtgg atgccatctg cacccaccac   2820

cctgacccca aaagccctag gctggacaga gagcagctgt attgggagct gagccagctg   2880

acccacaata tcactgagct gggcccctat gccctggaca acgacagcct ctttgtcaat   2940

ggtttcactc atcggagctc tgtgtccacc accagcactg ccagccatct cctgatacta   3000

ttcaccctca acttcaccat cactaacctg cggtatgagg agaacatgtg gcctggctcc   3060

aggaagttca acactacaga gagggtcctt cagggcctgc taaggccctt gttcaagaac   3120

accagtgttg gccctctgta ctctggctgc aggctgacct tgctcaggcc agagaaagat   3180

ggggaagcca ccggagtgga tgccatctgc acccaccgcc ctgaccccac aggccctggg   3240

ctggacagag agcagctgta tttggagctg agccagctga cccacagcat cactgagctg   3300

ggcccctaca cactggacag ggacagtctc tatgtcaatg gtttcaccca tcggagctct   3360

gtacccacca ccagcaccgg ggtggtcagc gaggagccat tcacactgaa cttcaccatc   3420

aacaacctgc gctacatggc ggacatgggc caacccggct ccctcaagtt caacatcaca   3480

gacaacgtca tgcagcacct gctcagtcct ttgttccaga ggagcagcct gggtgcacgg   3540

tacacaggct gcagggtcat cgcactaagg tctgtgaaga acggtgctga gacacgggtg   3600

gacctcctct gcacctacct gcagcccctc agcggcccag gtctgcctat caagcaggtg   3660

ttccatgagc tgagccagca gacccatggc atcacccggc tgggccccta ctctctggac   3720

aaagacagcc tctaccttaa cggttacaat gaacctggtc cagatgagcc tcctacaact   3780

cccaagccag ccaccacatt cctgcctcct ctgtcagaag ccacaacagc catggggtac   3840

cacctgaaga ccctcacact caacttcacc atctccaatc tccagtattc accagatatg   3900

ggcaagggct cagctacatt caactccacc gagggggtcc ttcagcacct gctcagaccc   3960

ttgttccaga agagcagcat gggccccttc tacttgggtt gccaactgat ctccctcagg   4020

cctgagaagg atggggcagc cactggtgtg gacaccacct gcacctacca ccctgaccct   4080

gtgggccccg ggctggacat acagcagctt tactgggagc tgagtcagct gacccatggt   4140

gtcacccaac tgggcttcta tgtcctggac agggatagcc tcttcatcaa tggctatgca   4200

ccccagaatt tatcaatccg gggcgagtac cagataaatt tccacattgt caactggaac   4260

ctcagtaatc cagaccccac atcctcagag tacatcaccc tgctgaggga catccaggac   4320

aaggtcacca cactctacaa aggcagtcaa ctacatgaca cattccgctt ctgcctggtc   4380

accaacttga cgatggactc cgtgttggtc actgtcaagg cattgttctc ctccaatttg   4440

gaccccagcc tggtggagca agtctttcta gataagaccc tgaatgcctc attccattgg   4500

ctgggctcca cctaccagtt ggtggacatc catgtgacag aaatggagtc atcagtttat   4560

caaccaacaa gcagctccag cacccagcac ttctacctga atttcaccat caccaaccta   4620

ccatattccc aggacaaagc ccagccaggc accaccaatt accagaggaa caaaaggaat   4680

attgaggatg cgctcaacca actcttccga aacagcagca tcaagagtta tttttctgac   4740

tgtcaagttt caacattcag gtctgtcccc aacaggcacc acaccggggt ggactccctg   4800

tgtaacttct cgccactggc tcggagagta gacagagttg ccatctatga ggaatttctg   4860

cggatgaccc ggaatggtac ccagctgcag aacttcaccc tggacaggag cagtgtcctt   4920

gtggatgggt attctcccaa cagaaatgag cccttaactg ggaattctga ccttcccttc   4980

tgggctgtca tcctcatcgg cttggcagga ctcctgggag tcatcacatg cctgatctgc   5040

ggtgtcctgg tgaccacccg ccggcggaag aaggaaggag aatacaacgt ccagcaacag   5100

tgcccaggct actaccagtc acacctagac ctggaggatc tgcaatgact ggaacttgcc   5160

ggtgcctggg gtgcctttcc cccagccagg gtccaaagaa gcttggctgg ggcagaaata   5220

aaccatattg gtcggacac                                                5239


<210>  9095
<211>  1714
<212>  PRT
<213>  Homo sapiens

<400>  9095

Met Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu 
1               5                   10                  15


Thr Leu Leu Arg Ser Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Ala 
            20                  25                  30


Ile Cys Thr His Arg Leu Asp Pro Lys Ser Pro Gly Val Asp Arg Glu 
        35                  40                  45


Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr Asn Gly Ile Lys Glu Leu 
    50                  55                  60


Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Pro Gly 
65                  70                  75                  80


Thr Ser Thr Val Asp Leu Gly Thr Ser Gly Thr Pro Ser Ser Leu Pro 
                85                  90                  95


Ser Pro Thr Ser Ala Gly Pro Leu Leu Val Pro Phe Thr Leu Asn Phe 
            100                 105                 110


Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met His His Pro Gly Ser 
        115                 120                 125


Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Gly Pro 
    130                 135                 140


Met Phe Lys Asn Thr Ser Val Gly Leu Leu Tyr Ser Gly Cys Arg Leu 
145                 150                 155                 160


Thr Leu Leu Arg Pro Glu Lys Asn Gly Ala Ala Thr Gly Met Asp Ala 
                165                 170                 175


Ile Cys Ser His Arg Leu Asp Pro Lys Ser Pro Gly Leu Asn Arg Glu 
            180                 185                 190


Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr His Gly Ile Lys Glu Leu 
        195                 200                 205


Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe Thr 
    210                 215                 220


His Arg Ser Ser Val Ala Pro Thr Ser Thr Pro Gly Thr Ser Thr Val 
225                 230                 235                 240


Asp Leu Gly Thr Ser Gly Thr Pro Ser Ser Leu Pro Ser Pro Thr Thr 
                245                 250                 255


Ala Val Pro Leu Leu Val Pro Phe Thr Leu Asn Phe Thr Ile Thr Asn 
            260                 265                 270


Leu Gln Tyr Gly Glu Asp Met Arg His Pro Gly Ser Arg Lys Phe Asn 
        275                 280                 285


Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Gly Pro Leu Phe Lys Asn 
    290                 295                 300


Ser Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Ile Ser Leu Arg 
305                 310                 315                 320


Ser Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Ala Ile Cys Thr His 
                325                 330                 335


His Leu Asn Pro Gln Ser Pro Gly Leu Asp Arg Glu Gln Leu Tyr Trp 
            340                 345                 350


Gln Leu Ser Gln Met Thr Asn Gly Ile Lys Glu Leu Gly Pro Tyr Thr 
        355                 360                 365


Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe Thr His Arg Ser Ser 
    370                 375                 380


Gly Leu Thr Thr Ser Thr Thr Gly Pro Leu Leu Val Pro Phe Thr Leu 
385                 390                 395                 400


Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asn Met Gly His Pro 
                405                 410                 415


Gly Ser Arg Lys Phe Asn Ile Thr Glu Ser Val Leu Gln Gly Leu Leu 
            420                 425                 430


Lys Pro Leu Phe Lys Ser Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys 
        435                 440                 445


Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Val Ala Thr Arg Val 
    450                 455                 460


Asp Ala Ile Cys Thr His Arg Pro Asp Pro Lys Ile Pro Gly Leu Asp 
465                 470                 475                 480


Arg Gln Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr His Ser Ile Thr 
                485                 490                 495


Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu Tyr Val Asn Gly 
            500                 505                 510


Phe Thr Gln Arg Ser Ser Val Pro Thr Thr Ser Thr Pro Gly Thr Phe 
        515                 520                 525


Thr Val Gln Pro Glu Thr Ser Glu Thr Pro Ser Ser Leu Pro Gly Pro 
    530                 535                 540


Thr Ala Thr Gly Pro Val Leu Leu Pro Phe Thr Leu Asn Phe Thr Ile 
545                 550                 555                 560


Thr Asn Leu Gln Tyr Glu Glu Asp Met Arg Arg Pro Gly Ser Arg Lys 
                565                 570                 575


Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Met Pro Leu Phe 
            580                 585                 590


Lys Asn Thr Ser Val Ser Ser Leu Tyr Ser Gly Cys Arg Leu Thr Leu 
        595                 600                 605


Leu Arg Pro Glu Lys Asp Gly Ala Ala Thr Arg Val Asp Ala Val Cys 
    610                 615                 620


Thr His Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp Arg Glu Arg Leu 
625                 630                 635                 640


Tyr Trp Lys Leu Ser Gln Leu Thr His Gly Ile Thr Glu Leu Gly Pro 
                645                 650                 655


Tyr Thr Leu Asp Arg His Ser Leu Tyr Val Asn Gly Phe Thr His Gln 
            660                 665                 670


Ser Ser Met Thr Thr Thr Arg Thr Pro Asp Thr Ser Thr Met His Leu 
        675                 680                 685


Ala Thr Ser Arg Thr Pro Ala Ser Leu Ser Gly Pro Met Thr Ala Ser 
    690                 695                 700


Pro Leu Leu Val Leu Phe Thr Ile Asn Phe Thr Ile Thr Asn Leu Arg 
705                 710                 715                 720


Tyr Glu Glu Asn Met His His Pro Gly Ser Arg Lys Phe Asn Thr Thr 
                725                 730                 735


Glu Arg Val Leu Gln Gly Leu Leu Arg Pro Val Phe Lys Asn Thr Ser 
            740                 745                 750


Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Lys 
        755                 760                 765


Lys Asp Gly Ala Ala Thr Lys Val Asp Ala Ile Cys Thr Tyr Arg Pro 
    770                 775                 780


Asp Pro Lys Ser Pro Gly Leu Asp Arg Glu Gln Leu Tyr Trp Glu Leu 
785                 790                 795                 800


Ser Gln Leu Thr His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp 
                805                 810                 815


Arg Asp Ser Leu Tyr Val Asn Gly Phe Thr Gln Arg Ser Ser Val Pro 
            820                 825                 830


Thr Thr Ser Ile Pro Gly Thr Pro Thr Val Asp Leu Gly Thr Ser Gly 
        835                 840                 845


Thr Pro Val Ser Lys Pro Gly Pro Ser Ala Ala Ser Pro Leu Leu Val 
    850                 855                 860


Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Arg Tyr Glu Glu Asn 
865                 870                 875                 880


Met Gln His Pro Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu 
                885                 890                 895


Gln Gly Leu Leu Arg Ser Leu Phe Lys Ser Thr Ser Val Gly Pro Leu 
            900                 905                 910


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Thr 
        915                 920                 925


Ala Thr Gly Val Asp Ala Ile Cys Thr His His Pro Asp Pro Lys Ser 
    930                 935                 940


Pro Arg Leu Asp Arg Glu Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr 
945                 950                 955                 960


His Asn Ile Thr Glu Leu Gly Pro Tyr Ala Leu Asp Asn Asp Ser Leu 
                965                 970                 975


Phe Val Asn Gly Phe Thr His Arg Ser Ser Val Ser Thr Thr Ser Thr 
            980                 985                 990


Ala Ser His Leu Leu Ile Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn 
        995                 1000                1005


Leu Arg Tyr Glu Glu Asn Met Trp Pro Gly Ser Arg Lys Phe Asn Thr 
    1010                1015                1020


Thr Glu Arg Val Leu Gln Gly Leu Leu Arg Pro Leu Phe Lys Asn Thr 
1025                1030                1035                1040


Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro 
                1045                1050                1055


Glu Lys Asp Gly Glu Ala Thr Gly Val Asp Ala Ile Cys Thr His Arg 
            1060                1065                1070


Pro Asp Pro Thr Gly Pro Gly Leu Asp Arg Glu Gln Leu Tyr Leu Glu 
        1075                1080                1085


Leu Ser Gln Leu Thr His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu 
    1090                1095                1100


Asp Arg Asp Ser Leu Tyr Val Asn Gly Phe Thr His Arg Ser Ser Val 
1105                1110                1115                1120


Pro Thr Thr Ser Thr Gly Val Val Ser Glu Glu Pro Phe Thr Leu Asn 
                1125                1130                1135


Phe Thr Ile Asn Asn Leu Arg Tyr Met Ala Asp Met Gly Gln Pro Gly 
            1140                1145                1150


Ser Leu Lys Phe Asn Ile Thr Asp Asn Val Met Gln His Leu Leu Ser 
        1155                1160                1165


Pro Leu Phe Gln Arg Ser Ser Leu Gly Ala Arg Tyr Thr Gly Cys Arg 
    1170                1175                1180


Val Ile Ala Leu Arg Ser Val Lys Asn Gly Ala Glu Thr Arg Val Asp 
1185                1190                1195                1200


Leu Leu Cys Thr Tyr Leu Gln Pro Leu Ser Gly Pro Gly Leu Pro Ile 
                1205                1210                1215


Lys Gln Val Phe His Glu Leu Ser Gln Gln Thr His Gly Ile Thr Arg 
            1220                1225                1230


Leu Gly Pro Tyr Ser Leu Asp Lys Asp Ser Leu Tyr Leu Asn Gly Tyr 
        1235                1240                1245


Asn Glu Pro Gly Pro Asp Glu Pro Pro Thr Thr Pro Lys Pro Ala Thr 
    1250                1255                1260


Thr Phe Leu Pro Pro Leu Ser Glu Ala Thr Thr Ala Met Gly Tyr His 
1265                1270                1275                1280


Leu Lys Thr Leu Thr Leu Asn Phe Thr Ile Ser Asn Leu Gln Tyr Ser 
                1285                1290                1295


Pro Asp Met Gly Lys Gly Ser Ala Thr Phe Asn Ser Thr Glu Gly Val 
            1300                1305                1310


Leu Gln His Leu Leu Arg Pro Leu Phe Gln Lys Ser Ser Met Gly Pro 
        1315                1320                1325


Phe Tyr Leu Gly Cys Gln Leu Ile Ser Leu Arg Pro Glu Lys Asp Gly 
    1330                1335                1340


Ala Ala Thr Gly Val Asp Thr Thr Cys Thr Tyr His Pro Asp Pro Val 
1345                1350                1355                1360


Gly Pro Gly Leu Asp Ile Gln Gln Leu Tyr Trp Glu Leu Ser Gln Leu 
                1365                1370                1375


Thr His Gly Val Thr Gln Leu Gly Phe Tyr Val Leu Asp Arg Asp Ser 
            1380                1385                1390


Leu Phe Ile Asn Gly Tyr Ala Pro Gln Asn Leu Ser Ile Arg Gly Glu 
        1395                1400                1405


Tyr Gln Ile Asn Phe His Ile Val Asn Trp Asn Leu Ser Asn Pro Asp 
    1410                1415                1420


Pro Thr Ser Ser Glu Tyr Ile Thr Leu Leu Arg Asp Ile Gln Asp Lys 
1425                1430                1435                1440


Val Thr Thr Leu Tyr Lys Gly Ser Gln Leu His Asp Thr Phe Arg Phe 
                1445                1450                1455


Cys Leu Val Thr Asn Leu Thr Met Asp Ser Val Leu Val Thr Val Lys 
            1460                1465                1470


Ala Leu Phe Ser Ser Asn Leu Asp Pro Ser Leu Val Glu Gln Val Phe 
        1475                1480                1485


Leu Asp Lys Thr Leu Asn Ala Ser Phe His Trp Leu Gly Ser Thr Tyr 
    1490                1495                1500


Gln Leu Val Asp Ile His Val Thr Glu Met Glu Ser Ser Val Tyr Gln 
1505                1510                1515                1520


Pro Thr Ser Ser Ser Ser Thr Gln His Phe Tyr Leu Asn Phe Thr Ile 
                1525                1530                1535


Thr Asn Leu Pro Tyr Ser Gln Asp Lys Ala Gln Pro Gly Thr Thr Asn 
            1540                1545                1550


Tyr Gln Arg Asn Lys Arg Asn Ile Glu Asp Ala Leu Asn Gln Leu Phe 
        1555                1560                1565


Arg Asn Ser Ser Ile Lys Ser Tyr Phe Ser Asp Cys Gln Val Ser Thr 
    1570                1575                1580


Phe Arg Ser Val Pro Asn Arg His His Thr Gly Val Asp Ser Leu Cys 
1585                1590                1595                1600


Asn Phe Ser Pro Leu Ala Arg Arg Val Asp Arg Val Ala Ile Tyr Glu 
                1605                1610                1615


Glu Phe Leu Arg Met Thr Arg Asn Gly Thr Gln Leu Gln Asn Phe Thr 
            1620                1625                1630


Leu Asp Arg Ser Ser Val Leu Val Asp Gly Tyr Ser Pro Asn Arg Asn 
        1635                1640                1645


Glu Pro Leu Thr Gly Asn Ser Asp Leu Pro Phe Trp Ala Val Ile Leu 
    1650                1655                1660


Ile Gly Leu Ala Gly Leu Leu Gly Val Ile Thr Cys Leu Ile Cys Gly 
1665                1670                1675                1680


Val Leu Val Thr Thr Arg Arg Arg Lys Lys Glu Gly Glu Tyr Asn Val 
                1685                1690                1695


Gln Gln Gln Cys Pro Gly Tyr Tyr Gln Ser His Leu Asp Leu Glu Asp 
            1700                1705                1710


Leu Gln 



<210>  9096
<211>  17347
<212>  DNA
<213>  Homo sapiens

<400>  9096
caacagagag aagtgcttct ctttctggaa tgcccactgg tgctactact aaggtctcca     60

gaacagaagc cctctcctta ggcagaacat ccaccccagg tcctgctcaa tccacaatat    120

caccagaaat ctccacggaa accatcacta gaatttctac tcccctcacc acgacaggat    180

cagcagaaat gaccatcacc cccaaaacag gtcattctgg ggcatcctca caaggtacct    240

ttaccttgga cacatcaagc agagcctcct ggccaggaac tcactcagct gcaactcaca    300

gatctccaca ctcagggatg accactccta tgagcagagg tcctgaggat gtgtcatggc    360

caagccgccc atcagtggaa aaaactagcc ctccatcttc cctggtgtct ttatctgcag    420

taacctcacc ttcgccactt tattccacac catctgagag tagccactca tctcctctcc    480

gggtgacttc tcttttcacc cctgtcatga tgaagaccac agacatgttg gacacaagct    540

tggaacctgt gaccacttca cctcccagta tgaatatcac ctcagatgag agtctggcca    600

cttctaaagc caccatggag acagaggcaa ttcagctttc agaaaacaca gctgtgactc    660

agatgggcac catcagcgct agacaagaat tctattcctc ttatccaggc ctcccagagc    720

catccaaagt gacatctcca gtggtcacct cttccaccat aaaagacatt gtttctacaa    780

ccatacctgc ttcctctgag ataacaagaa ttgagatgga gtcaacatcc accctgaccc    840

ccacaccaag ggagaccagc acctcccagg agatccactc agccacaaag ccaagcactg    900

ttccttacaa ggcactcact agtgccacga ttgaggactc catgacacaa gtcatgtcct    960

ctagcagagg acctagccct gatcagtcca caatgtcaca agacatatcc actgaagtga   1020

tcaccaggct ctctacctcc cccatcaaga cagaatctac agaaatgacc attaccaccc   1080

aaacaggttc tcctggggct acatcaaggg gtacccttac cttggacact tcaacaactt   1140

ttatgtcagg gacccactca actgcatctc aaggattttc acactcacag atgaccgctc   1200

ttatgagtag aactcctgga gatgtgccat ggctaagcca tccctctgtg gaagaagcca   1260

gctctgcctc tttctcactg tcttcacctg tcatgacctc atcttctccc gtttcttcca   1320

cattaccaga cagcatccac tcttcttcgc ttcctgtgac atcacttctc acctcagggc   1380

tggtgaagac cacagagctg ttgggcacaa gctcagaacc tgaaaccagt tcacccccaa   1440

atttgagcag cacctcagct gaaatactgg ccatcactga agtcactaca gatacagaga   1500

aactggagat gaccaatgtg gtaacctcag gttatacaca tgaatctcct tcctctgtcc   1560

tagctgactc agtgacaaca aaggccacat cttcaatggg tatcacctac cccacaggag   1620

atacaaatgt tctcacatca acccctgcct tctctgacac cagtaggatt caaacaaagt   1680

caaagctctc actgactcct gggttgatgg agaccagcat ctctgaagag accagctctg   1740

ccacagaaaa aagcactgtc ctttctagtg tgcccactgg tgctactact gaggtctcca   1800

ggacagaagc catctcttct agcagaacat ccatcccagg ccctgctcaa tccacaatgt   1860

catcagacac ctccatggaa accatcacta gaatttctac ccccctcaca aggaaagaat   1920

caacagacat ggccatcacc cccaaaacag gtccttctgg ggctacctcg cagggtacct   1980

ttaccttgga ctcatcaagc acagcctcct ggccaggaac tcactcagct acaactcaga   2040

gatttccaca gtcagtggtg acaactccta tgagcagagg tcctgaggat gtgtcatggc   2100

caagcccgct gtctgtggaa aaaaacagcc ctccatcttc cctggtatct tcatcttcag   2160

taacctcacc ttcgccactt tattccacac catctgggag tagccactcc tctcctgtcc   2220

ctgtcacttc tcttttcacc tctatcatga tgaaggccac agacatgttg gatgcaagtt   2280

tggaacctga gaccacttca gctcccaata tgaatatcac ctcagatgag agtctggccg   2340

cttctaaagc caccacggag acagaggcaa ttcacgtttt tgaaaataca gcagcgtccc   2400

atgtggaaac caccagtgct acagaggaac tctattcctc ttccccaggc ttctcagagc   2460

caacaaaagt gatatctcca gtggtcacct cttcctctat aagagacaac atggtttcca   2520

caacaatgcc tggctcctct ggcattacaa ggattgagat agagtcaatg tcatctctga   2580

cccctggact gagggagacc agaacctccc aggacatcac ctcatccaca gagacaagca   2640

ctgtccttta caagatgccc tctggtgcca ctcctgaggt ctccaggaca gaagttatgc   2700

cctctagcag aacatccatt cctggccctg ctcagtccac aatgtcacta gacatctccg   2760

atgaagttgt caccaggctg tctacctctc ccatcatgac agaatctgca gaaataacca   2820

tcaccaccca aacaggttat tctctggcta catcccaggt tacccttccc ttgggcacct   2880

caatgacctt tttgtcaggg acccactcaa ctatgtctca aggactttca cactcagaga   2940

tgaccaatct tatgagcagg ggtcctgaaa gtctgtcatg gacgagccct cgctttgtgg   3000

aaacaactag atcttcctct tctctgacat cattacctct cacgacctca ctttctcctg   3060

tgtcctccac attactagac agtagcccct cctctcctct tcctgtgact tcacttatcc   3120

tcccaggcct ggtgaagact acagaagtgt tggatacaag ctcagagcct aaaaccagtt   3180

catctccaaa tttgagcagc acctcagttg aaataccggc cacctctgaa atcatgacag   3240

atacagagaa aattcatcct tcctcaaaca cagcggtggc caaagtgagg acctccagtt   3300

ctgttcatga atctcattcc tctgtcctag ctgactcaga aacaaccata accatacctt   3360

caatgggtat cacctccgct gtggacgata ccactgtttt cacatcaaat cctgccttct   3420

ctgagactag gaggattccg acagagccaa cattctcatt gactcctgga ttcagggaga   3480

ctagcacctc tgaagagacc acctcaatca cagaaacaag tgcagtcctt tatggagtgc   3540

ccactagtgc tactactgaa gtctccatga cagaaatcat gtcctctaat agaatacaca   3600

tccctgactc tgatcagtcc acgatgtctc cagacatcat cactgaagtg atcaccaggc   3660

tctcttcctc atccatgatg tcagaatcaa cacaaatgac catcaccacc caaaaaagtt   3720

ctcctggggc tacagcacag agtactctta ccttggccac aacaacagcc cccttggcaa   3780

ggacccactc aactgttcct cctagatttt tacactcaga gatgacaact cttatgagta   3840

ggagtcctga aaatccatca tggaagagct ctctctttgt ggaaaaaact agctcttcat   3900

cttctctgtt gtccttacct gtcacgacct caccttctgt ttcttccaca ttaccgcaga   3960

gtatcccttc ctcctctttt tctgtgactt cactcctcac cccaggcatg gtgaagacta   4020

cagacacaag cacagaacct ggaaccagtt tatctccaaa tctgagtggc acctcagttg   4080

aaatactggc tgcctctgaa gtcaccacag atacagagaa aattcatcct tcttcaagca   4140

tggcagtgac caatgtggga accaccagtt ctggacatga actatattcc tctgtttcaa   4200

tccactcgga gccatccaag gctacatacc cagtgggtac tccctcttcc atggctgaaa   4260

cctctatttc cacatcaatg cctgctaatt ttgagaccac aggatttgag gctgagccat   4320

tttctcattt gacttctgga tttaggaaga caaacatgtc cctggacacc agctcagtca   4380

caccaacaaa tacaccttct tctcctgggt ccactcacct tttacagagt tccaagactg   4440

atttcacctc ttctgcaaaa acatcatccc cagactggcc tccagcctca cagtatactg   4500

aaattccagt ggacataatc acccccttta atgcttctcc atctattacg gagtccactg   4560

ggataacctc cttcccagaa tccaggttta ctatgtctgt aacagaaagt actcatcatc   4620

tgagtacaga tttgctgcct tcagctgaga ctatttccac tggcacagtg atgccttctc   4680

tatcagaggc catgacttca tttgccacca ctggagttcc acgagccatc tcaggttcag   4740

gtagtccatt ctctaggaca gagtcaggcc ctggggatgc tactctgtcc accattgcag   4800

agagcctgcc ttcatccact cctgtgccat tctcctcttc aaccttcact accactgatt   4860

cttcaaccat cccagccctc catgagataa cttcctcttc agctacccca tatagagtgg   4920

acaccagtct tgggacagag agcagcacta ctgaaggacg cttggttatg gtcagtactt   4980

tggacacttc aagccaacca ggcaggacat cttcatcacc cattttggat accagaatga   5040

cagagagcgt tgagctggga acagtgacaa gtgcttatca agttccttca ctctcaacac   5100

ggttgacaag aactgatggc attatggaac acatcacaaa aatacccaat gaagcagcac   5160

acagaggtac cataagacca gtcaaaggcc ctcagacatc cacttcgcct gccagtccta   5220

aaggactaca cacaggaggg acaaaaagaa tggagaccac caccacagct ctgaagacca   5280

ccaccacagc tctgaagacc acttccagag ccaccttgac caccagtgtc tatactccca   5340

ctttgggaac actgactccc ctcaatgcat caatgcaaat ggccagcaca atccccacag   5400

aaatgatgat cacaacccca tatgttttcc ctgatgttcc agaaacgaca tcctcattgg   5460

ctaccagcct gggagcagaa accagcacag ctcttcccag gacaacccca tctgttttca   5520

atagagaatc agagaccaca gcctcactgg tctctcgttc tggggcagag agaagtccgg   5580

ttattcaaac tctagatgtt tcttctagtg agccagatac aacagcttca tgggttatcc   5640

atcctgcaga gaccatccca actgtttcca agacaacccc caattttttc cacagtgaat   5700

tagacactgt atcttccaca gccaccagtc atggggcaga cgtcagctca gccattccaa   5760

caaatatctc acctagtgaa ctagatgcac tgaccccact ggtcactatt tcggggacag   5820

atactagtac aacattccca acactgacta agtccccaca tgaaacagag acaagaacca   5880

catggctcac tcatcctgca gagaccagct caactattcc cagaacaatc cccaattttt   5940

ctcatcatga atcagatgcc acaccttcaa tagccaccag tcctggggca gaaaccagtt   6000

cagctattcc aattatgact gtctcacctg gtgcagaaga tctggtgacc tcacaggtca   6060

ctagttctgg gacagacaga aatatgacta ttccaacttt gactctttct cctggtgaac   6120

caaagacgat agcctcatta gtcacccatc ctgaagcaca gacaagttcg gccattccaa   6180

cttcaactat ctcgcctgct gtatcacggt tggtgacctc aatggtcacc agtttggcgg   6240

caaagacaag tacaactaat cgagctctga caaactcccc tggtgaacca gctacaacag   6300

tttcattggt cacgcatcct gcacagacca gcccaacagt tccctggaca acttccattt   6360

ttttccatag taaatcagac accacacctt caatgaccac cagtcatggg gcagaatcca   6420

gttcagctgt tccaactcca actgtttcaa ctgaggtacc aggagtagtg acccctttgg   6480

tcaccagttc tagggcagtg atcagtacaa ctattccaat tctgactctt tctcctggtg   6540

aaccagagac cacaccttca atggccacca gtcatgggga agaagccagt tctgctattc   6600

caactccaac tgtttcacct ggggtaccag gagtggtgac ctctctggtc actagttcta   6660

gggcagtgac tagtacaact attccaattc tgactttttc tcttggtgaa ccagagacca   6720

caccttcaat ggccaccagt catgggacag aagctggctc agctgttcca actgttttac   6780

ctgaggtacc aggaatggtg acctctctgg ttgctagttc tagggcagta accagtacaa   6840

ctcttccaac tctgactctt tctcctggtg aaccagagac cacaccttca atggccacca   6900

gtcatggggc agaagccagc tcaactgttc caactgtttc acctgaggta ccaggagtgg   6960

tgacctctct ggtcactagt tctagtggag taaacagtac aagtattcca actctgattc   7020

tttctcctgg tgaactagaa accacacctt caatggccac cagtcatggg gcagaagcca   7080

gctcagctgt tccaactcca actgtttcac ctggggtatc aggagtggtg acccctctgg   7140

tcactagttc cagggcagtg accagtacaa ctattccaat tctaactctt tcttctagtg   7200

agccagagac cacaccttca atggccacca gtcatggggt agaagccagc tcagctgttc   7260

taactgtttc acctgaggta ccaggaatgg tgacctctct ggtcactagt tctagagcag   7320

taaccagtac aactattcca actctgacta tttcttctga tgaaccagag accacaactt   7380

cattggtcac ccattctgag gcaaagatga tttcagccat tccaacttta gctgtctccc   7440

ctactgtaca agggctggtg acttcactgg tcactagttc tgggtcagag accagtgcgt   7500

tttcaaatct aactgttgcc tcaagtcaac cagagaccat agactcatgg gtcgctcatc   7560

ctgggacaga agcaagttct gttgttccaa ctttgactgt ctccactggt gagccgttta   7620

caaatatctc attggtcacc catcctgcag agagtagctc aactcttccc aggacaacct   7680

caaggttttc ccacagtgaa ttagacacta tgccttctac agtcaccagt cctgaggcag   7740

aatccagctc agccatttca acaactattt cacctggtat accaggtgtg ctgacatcac   7800

tggtcactag ctctgggaga gacatcagtg caacttttcc aacagtgcct gagtccccac   7860

atgaatcaga ggcaacagcc tcatgggtta ctcatcctgc agtcaccagc acaacagttc   7920

ccaggacaac ccctaattat tctcatagtg aaccagacac cacaccatca atagccacca   7980

gtcctggggc agaagccact tcagattttc caacaataac tgtctcacct gatgtaccag   8040

atatggtaac ctcacaggtc actagttctg ggacagacac cagtataact attccaactc   8100

tgactctttc ttctggtgag ccagagacca caacctcatt tatcacctat tctgagacac   8160

acacaagttc agccattcca actctccctg tctcccctgg tgcatcaaag atgctgacct   8220

cactggtcat cagttctggg acagacagca ctacaacttt cccaacactg acggagaccc   8280

catatgaacc agagacaaca gccatacagc tcattcatcc tgcagagacc aacacaatgg   8340

ttcccaggac aactcccaag ttttcccata gtaagtcaga caccacactc ccagtagcca   8400

tcaccagtcc tgggccagaa gccagttcag ctgtttcaac gacaactatc tcacctgata   8460

tgtcagatct ggtgacctca ctggtcccta gttctgggac agacaccagt acaaccttcc   8520

caacattgag tgagacccca tatgaaccag agactacagc cacgtggctc actcatcctg   8580

cagaaaccag cacaacggtt tctgggacaa ttcccaactt ttcccatagg ggatcagaca   8640

ctgcaccctc aatggtcacc agtcctggag tagacacgag gtcaggtgtt ccaactacaa   8700

ccatcccacc cagtatacca ggggtagtga cctcacaggt cactagttct gcaacagaca   8760

ctagtacagc tattccaact ttgactcctt ctcctggtga accagagacc acagcctcat   8820

cagctaccca tcctgggaca cagactggct tcactgttcc aattcggact gttccctcta   8880

gtgagccaga tacaatggct tcctgggtca ctcatcctcc acagaccagc acacctgttt   8940

ccagaacaac ctccagtttt tcccatagta gtccagatgc cacacctgta atggccacca   9000

gtcctaggac agaagccagt tcagctgtac tgacaacaat ctcacctggt gcaccagaga   9060

tggtgacttc acagatcact agttctgggg cagcaaccag tacaactgtt ccaactttga   9120

ctcattctcc tggtatgcca gagaccacag ccttattgag cacccatccc agaacagaga   9180

caagtaaaac atttcctgct tcaactgtgt ttcctcaagt atcagagacc acagcctcac   9240

tcaccattag acctggtgca gagactagca cagctctccc aactcagaca acatcctctc   9300

tcttcaccct acttgtaact ggaaccagca gagttgatct aagtccaact gcttcacctg   9360

gtgtttctgc aaaaacagcc ccactttcca cccatccagg gacagaaacc agcacaatga   9420

ttccaacttc aactctttcc cttggtttac tagagactac aggcttactg gccaccagct   9480

cttcagcaga gaccagcacg agtactctaa ctctgactgt ttcccctgct gtctctgggc   9540

tttccagtgc ctctataaca actgataagc cccaaactgt gacctcctgg aacacagaaa   9600

cctcaccatc tgtaacttca gttggacccc cagaattttc caggactgtc acaggcacca   9660

ctatgacctt gataccatca gagatgccaa caccacctaa aaccagtcat ggagaaggag   9720

tgagtccaac cactatcttg agaactacaa tggttgaagc cactaattta gctaccacag   9780

gttccagtcc cactgtggcc aagacaacaa ccaccttcaa tacactggct ggaagcctct   9840

ttactcctct gaccacacct gggatgtcca ccttggcctc tgagagtgtg acctcaagaa   9900

caagttataa ccatcggtcc tggatctcca ccaccagcag ttataaccgt cggtactgga   9960

cccctgccac cagcactcca gtgacttcta cattctcccc agggatttcc acatcctcca  10020

tccccagctc cacagcagcc acagtcccat tcatggtgcc attcaccctc aacttcacca  10080

tcaccaacct gcagtacgag gaggacatgc ggcaccctgg ttccaggaag ttcaacgcca  10140

cagagagaga actgcagggt ctgctcaaac ccttgttcag gaatagcagt ctggaatacc  10200

tctattcagg ctgcagacta gcctcactca ggccagagaa ggatagctca gccacggcag  10260

tggatgccat ctgcacacat cgccctgacc ctgaagacct cggactggac agagagcgac  10320

tgtactggga gctgagcaat ctgacaaatg gcatccagga gctgggcccc tacaccctgg  10380

accggaacag tctctatgtc aatggtttca cccatcgaag ctctatgccc accaccagca  10440

ctcctgggac ctccacagtg gatgtgggaa cctcagggac tccatcctcc agccccagcc  10500

ccacgactgc tggccctctc ctgatgccgt tcaccctcaa cttcaccatc accaacctgc  10560

agtacgagga ggacatgcgt cgcactggct ccaggaagtt caacaccatg gagagtgtcc  10620

tgcagggtct gctcaagccc ttgttcaaga acaccagtgt tggccctctg tactctggct  10680

gcagattgac cttgctcagg cccgagaaag atggggcagc cactggagtg gatgccatct  10740

gcacccaccg ccttgacccc aaaagccctg gactcaacag ggagcagctg tactgggagc  10800

taagcaaact gaccaatgac attgaagagc tgggccccta caccctggac aggaacagtc  10860

tctatgtcaa tggtttcacc catcagagct ctgtgtccac caccagcact cctgggacct  10920

ccacagtgga tctcagaacc tcagggactc catcctccct ctccagcccc acaattatgg  10980

ctgctggccc tctcctggta ccattcaccc tcaacttcac catcaccaac ctgcagtatg  11040

gggaggacat gggtcaccct ggctccagga agttcaacac cacagagagg gtcctgcagg  11100

gtctgcttgg tcccatattc aagaacacca gtgttggccc tctgtactct ggctgcagac  11160

tgacctctct caggtctgag aaggatggag cagccactgg agtggatgcc atctgcatcc  11220

atcatcttga ccccaaaagc cctggactca acagagagcg gctgtactgg gagctgagcc  11280

aactgaccaa tggcatcaaa gagctgggcc cctacaccct ggacaggaac agtctctatg  11340

tcaatggttt cacccatcgg acctctgtgc ccaccagcag cactcctggg acctccacag  11400

tggaccttgg aacctcaggg actccattct ccctcccaag ccccgcaact gctggccctc  11460

tcctggtgct gttcaccctc aacttcacca tcaccaacct gaagtatgag gaggacatgc  11520

atcgccctgg ctccaggaag ttcaacacca ctgagagggt cctgcagact ctgcttggtc  11580

ctatgttcaa gaacaccagt gttggccttc tgtactctgg ctgcagactg accttgctca  11640

ggtccgagaa ggatggagca gccactggag tggatgccat ctgcacccac cgtcttgacc  11700

ccaaaagccc tggagtggac agggagcagc tatactggga gctgagccag ctgaccaatg  11760

gcatcaaaga gctgggcccc tacaccctgg acaggaacag tctctatgtc aatggtttca  11820

cccattggat ccctgtgccc accagcagca ctcctgggac ctccacagtg gaccttgggt  11880

cagggactcc atcctccctc cccagcccca caactgctgg ccctctcctg gtgccgttca  11940

ccctcaactt caccatcacc aacctgaagt acgaggagga catgcattgc cctggctcca  12000

ggaagttcaa caccacagag agagtcctgc agagtctgct tggtcccatg ttcaagaaca  12060

ccagtgttgg ccctctgtac tctggctgca gactgacctt gctcaggtcc gagaaggatg  12120

gagcagccac tggagtggat gccatctgca cccaccgtct tgaccccaaa agccctggag  12180

tggacaggga gcagctatac tgggagctga gccagctgac caatggcatc aaagagctgg  12240

gtccctacac cctggacaga aacagtctct atgtcaatgg tttcacccat cagacctctg  12300

cgcccaacac cagcactcct gggacctcca cagtggacct tgggacctca gggactccat  12360

cctccctccc cagccctaca tctgctggcc ctctcctggt gccattcacc ctcaacttca  12420

ccatcaccaa cctgcagtac gaggaggaca tgcatcaccc aggctccagg aagttcaaca  12480

ccacggagcg ggtcctgcag ggtctgcttg gtcccatgtt caagaacacc agtgtcggcc  12540

ttctgtactc tggctgcaga ctgaccttgc tcaggcctga gaagaatggg gcagccactg  12600

gaatggatgc catctgcagc caccgtcttg accccaaaag ccctggactc aacagagagc  12660

agctgtactg ggagctgagc cagctgaccc atggcatcaa agagctgggc ccctacaccc  12720

tggacaggaa cagtctctat gtcaatggtt tcacccatcg gagctctgtg gcccccacca  12780

gcactcctgg gacctccaca gtggaccttg ggacctcagg gactccatcc tccctcccca  12840

gccccacaac agctgttcct ctcctggtgc cgttcaccct caactttacc atcaccaatc  12900

tgcagtatgg ggaggacatg cgtcaccctg gctccaggaa gttcaacacc acagagaggg  12960

tcctgcaggg tctgcttggt cccttgttca agaactccag tgtcggccct ctgtactctg  13020

gctgcagact gatctctctc aggtctgaga aggatggggc agccactgga gtggatgcca  13080

tctgcaccca ccaccttaac cctcaaagcc ctggactgga cagggagcag ctgtactggc  13140

agctgagcca gatgaccaat ggcatcaaag agctgggccc ctacaccctg gaccggaaca  13200

gtctctacgt caatggtttc acccatcgga gctctgggct caccaccagc actccttgga  13260

cttccacagt tgaccttgga acctcaggga ctccatcccc cgtccccagc cccacaacca  13320

ccggccctct cctggtgcca ttcacactca acttcaccat cactaaccta cagtatgagg  13380

agaacatggg tcaccctggc tccaggaagt tcaacatcac ggagagtgtt ctgcagggtc  13440

tgctcaagcc cttgttcaag agcaccagtg ttggccctct gtattctggc tgcagactga  13500

ccttgctcag gcctgagaag gatggagtag ccaccagagt ggacgccatc tgcacccacc  13560

gccctgaccc caaaatccct gggctagaca gacagcagct atactgggag ctgagccagc  13620

tgacccacag catcactgag ctgggaccct acaccctgga tagggacagt ctctatgtca  13680

atggtttcac ccagcggagc tctgtgccca ccaccagcac tcctgggact ttcacagtac  13740

agccggaaac ctctgagact ccatcatccc tccctggccc cacagccact ggccctgtcc  13800

tgctgccatt caccctcaat tttaccatca ctaacctgca gtatgaggag gacatgcgtc  13860

gccctggctc caggaagttc aacaccacgg agagggtcct tcagggtctg cttatgccct  13920

tgttcaagaa caccagtgtc agctctctgt actctggttg cagactgacc ttgctcaggc  13980

ctgagaagga tggggcagcc accagagtgg atgctgtctg cacccatcgt cctgacccca  14040

aaagccctgg actggacaga gagcggctgt actggaagct gagccagctg acccacggca  14100

tcactgagct gggcccctac accctggaca ggcacagtct ctatgtcaat ggtttcaccc  14160

atcagagctc tatgacgacc accagaactc ctgatacctc cacaatgcac ctggcaacct  14220

cgagaactcc agcctccctg tctggaccca tgaccgccag ccctctcctg gtgctattca  14280

caattaactt caccatcact aacctgcggt atgaggagaa catgcatcac cctggctcta  14340

gaaagtttaa caccacggag agagtccttc agggtctgct caggcctgtg ttcaagaaca  14400

ccagtgttgg ccctctgtac tctggctgca gactgacctt gctcaggccc aagaaggatg  14460

gggcagccac caaagtggat gccatctgca cctaccgccc tgatcccaaa agccctggac  14520

tggacagaga gcagctatac tgggagctga gccagctgac ccacagcatc actgagctgg  14580

gcccctacac cctggacagg gacagtctct atgtcaatgg tttcacacag cggagctctg  14640

tgcccaccac tagcattcct gggaccccca cagtggacct gggaacatct gggactccag  14700

tttctaaacc tggtccctcg gctgccagcc ctctcctggt gctattcact ctcaacttca  14760

ccatcaccaa cctgcggtat gaggagaaca tgcagcaccc tggctccagg aagttcaaca  14820

ccacggagag ggtccttcag ggcctgctca ggtccctgtt caagagcacc agtgttggcc  14880

ctctgtactc tggctgcaga ctgactttgc tcaggcctga aaaggatggg acagccactg  14940

gagtggatgc catctgcacc caccaccctg accccaaaag ccctaggctg gacagagagc  15000

agctgtattg ggagctgagc cagctgaccc acaatatcac tgagctgggc ccctatgccc  15060

tggacaacga cagcctcttt gtcaatggtt tcactcatcg gagctctgtg tccaccacca  15120

gcactcctgg gacccccaca gtgttcaccc tcaacttcac catcactaac ctgcggtatg  15180

aggagaacat gtggcctggc tccaggaagt tcaacactac agagagggtc cttcagggcc  15240

tgctaaggcc cttgttcaag aacaccagtg ttggccctct gtactctggc tgcaggctga  15300

ccttgctcag gccagagaaa gatggggaag ccaccggagt ggatgccatc tgcacccacc  15360

gccctgaccc cacaggccct gggctggaca gagagcagct gtatttggag ctgagccagc  15420

tgacccacag catcactgag ctgggcccct acacactgga cagggacagt ctctatgtca  15480

atggccgggg tggtcagcga ggagccattc acactgaact tcaccatcaa caacctgcgc  15540

tacatggcgg acatgggcca acccggctcc ctcaagttca acatcacaga caacgtcatg  15600

cagcacctgc tcagtccttt gttccagagg agcagcctgg gtgcacggta cacaggctgc  15660

agggtcatcg cactaaggtc tgtgaagaac ggtgctgaga cacgggtgga cctcctctgc  15720

acctacctgc agcccctcag cggcccaggt ctgcctatca agcaggtgtt ccatgagctg  15780

agccagcaga cccatggcat cacccggctg ggcccctact ctctggacaa agacagcctc  15840

taccttaacg gttacaatga acctggtcca gatgagcctc ctacaactcc caagccagcc  15900

accacattcc tgcctcctct gtcagaagcc acaacagcca tggggtacca cctgaagacc  15960

ctcacactca acttcaccat ctccaatctc cagtattcac cagatatggg caagggctca  16020

gctacattca actccaccga gggggtcctt cagcacctgc tcagaccctt gttccagaag  16080

agcagcatgg gccccttcta cttgggttgc caactgatct ccctcaggcc tgagaaggat  16140

ggggcagcca ctggtgtgga caccacctgc acctaccacc ctgaccctgt gggccccggg  16200

ctggacatac agcagcttta ctgggagctg agtcagctga cccatggtgt cacccaactg  16260

ggcttctatg tcctggacag ggatagcctc ttcatcaatg gctatgcacc ccagaattta  16320

tcaatccggg gcgagtacca gataaatttc cacattgtca actggaacct cagtaatcca  16380

gaccccacat cctcagagta catcaccctg ctgagggaca tccaggacaa ggtcaccaca  16440

ctctacaaag gcagtcaact acatgacaca ttccgcttct gcctggtcac caacttgacg  16500

atggactccg tgttggtcac tgtcaaggca ttgttctcct ccaatttgga ccccagcctg  16560

gtggagcaag tctttctaga taagaccctg aatgcctcat tccattggct gggctccacc  16620

taccagttgg tggacatcca tgtgacagaa atggagtcat cagtttatca accaacaagc  16680

agctccagca cccagcactt ctacctgaat ttcaccatca ccaacctacc atattcccag  16740

gacaaagccc agccaggcac caccaattac cagaggaaca aaaggaatat tgaggatgcg  16800

ctcaaccaac tcttccgaaa cagcagcatc aagagttatt tttctgactg tcaagtttca  16860

acattcaggt ctgtccccaa caggcaccac accggggtgg actccctgtg taacttctcg  16920

ccactggctc ggagagtaga cagagttgcc atctatgagg aatttctgcg gatgacccgg  16980

aatggtaccc agctgcagaa cttcaccctg gacaggagca gtgtccttgt ggatgggtat  17040

tctcccaaca gaaatgagcc cttaactggg aattctgacc ttcccttctg ggctgtcatc  17100

ctcatcggct tggcaggact cctgggagtc atcacatgcc tgatctgcgg tgtcctggtg  17160

accacccgcc ggcggaagaa ggaaggagaa tacaacgtcc agcaacagtg cccaggctac  17220

taccagtcac acctagacct ggaggatctg caatgactgg aacttgccgg tgcctggggt  17280

gcctttcccc cagccagggt ccaaagaagc ttggctgggg cagaaataaa ccatattggt  17340

cggacac                                                            17347


<210>  9097
<211>  5222
<212>  PRT
<213>  Homo sapiens

<400>  9097

Met Pro Thr Gly Ala Thr Thr Lys Val Ser Arg Thr Glu Ala Leu Ser 
1               5                   10                  15


Leu Gly Arg Thr Ser Thr Pro Gly Pro Ala Gln Ser Thr Ile Ser Pro 
            20                  25                  30


Glu Ile Ser Thr Glu Thr Ile Thr Arg Ile Ser Thr Pro Leu Thr Thr 
        35                  40                  45


Thr Gly Ser Ala Glu Met Thr Ile Thr Pro Lys Thr Gly His Ser Gly 
    50                  55                  60


Ala Ser Ser Gln Gly Thr Phe Thr Leu Asp Thr Ser Ser Arg Ala Ser 
65                  70                  75                  80


Trp Pro Gly Thr His Ser Ala Ala Thr His Arg Ser Pro His Ser Gly 
                85                  90                  95


Met Thr Thr Pro Met Ser Arg Gly Pro Glu Asp Val Ser Trp Pro Ser 
            100                 105                 110


Arg Pro Ser Val Glu Lys Thr Ser Pro Pro Ser Ser Leu Val Ser Leu 
        115                 120                 125


Ser Ala Val Thr Ser Pro Ser Pro Leu Tyr Ser Thr Pro Ser Glu Ser 
    130                 135                 140


Ser His Ser Ser Pro Leu Arg Val Thr Ser Leu Phe Thr Pro Val Met 
145                 150                 155                 160


Met Lys Thr Thr Asp Met Leu Asp Thr Ser Leu Glu Pro Val Thr Thr 
                165                 170                 175


Ser Pro Pro Ser Met Asn Ile Thr Ser Asp Glu Ser Leu Ala Thr Ser 
            180                 185                 190


Lys Ala Thr Met Glu Thr Glu Ala Ile Gln Leu Ser Glu Asn Thr Ala 
        195                 200                 205


Val Thr Gln Met Gly Thr Ile Ser Ala Arg Gln Glu Phe Tyr Ser Ser 
    210                 215                 220


Tyr Pro Gly Leu Pro Glu Pro Ser Lys Val Thr Ser Pro Val Val Thr 
225                 230                 235                 240


Ser Ser Thr Ile Lys Asp Ile Val Ser Thr Thr Ile Pro Ala Ser Ser 
                245                 250                 255


Glu Ile Thr Arg Ile Glu Met Glu Ser Thr Ser Thr Leu Thr Pro Thr 
            260                 265                 270


Pro Arg Glu Thr Ser Thr Ser Gln Glu Ile His Ser Ala Thr Lys Pro 
        275                 280                 285


Ser Thr Val Pro Tyr Lys Ala Leu Thr Ser Ala Thr Ile Glu Asp Ser 
    290                 295                 300


Met Thr Gln Val Met Ser Ser Ser Arg Gly Pro Ser Pro Asp Gln Ser 
305                 310                 315                 320


Thr Met Ser Gln Asp Ile Ser Thr Glu Val Ile Thr Arg Leu Ser Thr 
                325                 330                 335


Ser Pro Ile Lys Thr Glu Ser Thr Glu Met Thr Ile Thr Thr Gln Thr 
            340                 345                 350


Gly Ser Pro Gly Ala Thr Ser Arg Gly Thr Leu Thr Leu Asp Thr Ser 
        355                 360                 365


Thr Thr Phe Met Ser Gly Thr His Ser Thr Ala Ser Gln Gly Phe Ser 
    370                 375                 380


His Ser Gln Met Thr Ala Leu Met Ser Arg Thr Pro Gly Asp Val Pro 
385                 390                 395                 400


Trp Leu Ser His Pro Ser Val Glu Glu Ala Ser Ser Ala Ser Phe Ser 
                405                 410                 415


Leu Ser Ser Pro Val Met Thr Ser Ser Ser Pro Val Ser Ser Thr Leu 
            420                 425                 430


Pro Asp Ser Ile His Ser Ser Ser Leu Pro Val Thr Ser Leu Leu Thr 
        435                 440                 445


Ser Gly Leu Val Lys Thr Thr Glu Leu Leu Gly Thr Ser Ser Glu Pro 
    450                 455                 460


Glu Thr Ser Ser Pro Pro Asn Leu Ser Ser Thr Ser Ala Glu Ile Leu 
465                 470                 475                 480


Ala Ile Thr Glu Val Thr Thr Asp Thr Glu Lys Leu Glu Met Thr Asn 
                485                 490                 495


Val Val Thr Ser Gly Tyr Thr His Glu Ser Pro Ser Ser Val Leu Ala 
            500                 505                 510


Asp Ser Val Thr Thr Lys Ala Thr Ser Ser Met Gly Ile Thr Tyr Pro 
        515                 520                 525


Thr Gly Asp Thr Asn Val Leu Thr Ser Thr Pro Ala Phe Ser Asp Thr 
    530                 535                 540


Ser Arg Ile Gln Thr Lys Ser Lys Leu Ser Leu Thr Pro Gly Leu Met 
545                 550                 555                 560


Glu Thr Ser Ile Ser Glu Glu Thr Ser Ser Ala Thr Glu Lys Ser Thr 
                565                 570                 575


Val Leu Ser Ser Val Pro Thr Gly Ala Thr Thr Glu Val Ser Arg Thr 
            580                 585                 590


Glu Ala Ile Ser Ser Ser Arg Thr Ser Ile Pro Gly Pro Ala Gln Ser 
        595                 600                 605


Thr Met Ser Ser Asp Thr Ser Met Glu Thr Ile Thr Arg Ile Ser Thr 
    610                 615                 620


Pro Leu Thr Arg Lys Glu Ser Thr Asp Met Ala Ile Thr Pro Lys Thr 
625                 630                 635                 640


Gly Pro Ser Gly Ala Thr Ser Gln Gly Thr Phe Thr Leu Asp Ser Ser 
                645                 650                 655


Ser Thr Ala Ser Trp Pro Gly Thr His Ser Ala Thr Thr Gln Arg Phe 
            660                 665                 670


Pro Gln Ser Val Val Thr Thr Pro Met Ser Arg Gly Pro Glu Asp Val 
        675                 680                 685


Ser Trp Pro Ser Pro Leu Ser Val Glu Lys Asn Ser Pro Pro Ser Ser 
    690                 695                 700


Leu Val Ser Ser Ser Ser Val Thr Ser Pro Ser Pro Leu Tyr Ser Thr 
705                 710                 715                 720


Pro Ser Gly Ser Ser His Ser Ser Pro Val Pro Val Thr Ser Leu Phe 
                725                 730                 735


Thr Ser Ile Met Met Lys Ala Thr Asp Met Leu Asp Ala Ser Leu Glu 
            740                 745                 750


Pro Glu Thr Thr Ser Ala Pro Asn Met Asn Ile Thr Ser Asp Glu Ser 
        755                 760                 765


Leu Ala Ala Ser Lys Ala Thr Thr Glu Thr Glu Ala Ile His Val Phe 
    770                 775                 780


Glu Asn Thr Ala Ala Ser His Val Glu Thr Thr Ser Ala Thr Glu Glu 
785                 790                 795                 800


Leu Tyr Ser Ser Ser Pro Gly Phe Ser Glu Pro Thr Lys Val Ile Ser 
                805                 810                 815


Pro Val Val Thr Ser Ser Ser Ile Arg Asp Asn Met Val Ser Thr Thr 
            820                 825                 830


Met Pro Gly Ser Ser Gly Ile Thr Arg Ile Glu Ile Glu Ser Met Ser 
        835                 840                 845


Ser Leu Thr Pro Gly Leu Arg Glu Thr Arg Thr Ser Gln Asp Ile Thr 
    850                 855                 860


Ser Ser Thr Glu Thr Ser Thr Val Leu Tyr Lys Met Pro Ser Gly Ala 
865                 870                 875                 880


Thr Pro Glu Val Ser Arg Thr Glu Val Met Pro Ser Ser Arg Thr Ser 
                885                 890                 895


Ile Pro Gly Pro Ala Gln Ser Thr Met Ser Leu Asp Ile Ser Asp Glu 
            900                 905                 910


Val Val Thr Arg Leu Ser Thr Ser Pro Ile Met Thr Glu Ser Ala Glu 
        915                 920                 925


Ile Thr Ile Thr Thr Gln Thr Gly Tyr Ser Leu Ala Thr Ser Gln Val 
    930                 935                 940


Thr Leu Pro Leu Gly Thr Ser Met Thr Phe Leu Ser Gly Thr His Ser 
945                 950                 955                 960


Thr Met Ser Gln Gly Leu Ser His Ser Glu Met Thr Asn Leu Met Ser 
                965                 970                 975


Arg Gly Pro Glu Ser Leu Ser Trp Thr Ser Pro Arg Phe Val Glu Thr 
            980                 985                 990


Thr Arg Ser Ser Ser Ser Leu Thr Ser Leu Pro Leu Thr Thr Ser Leu 
        995                 1000                1005


Ser Pro Val Ser Ser Thr Leu Leu Asp Ser Ser Pro Ser Ser Pro Leu 
    1010                1015                1020


Pro Val Thr Ser Leu Ile Leu Pro Gly Leu Val Lys Thr Thr Glu Val 
1025                1030                1035                1040


Leu Asp Thr Ser Ser Glu Pro Lys Thr Ser Ser Ser Pro Asn Leu Ser 
                1045                1050                1055


Ser Thr Ser Val Glu Ile Pro Ala Thr Ser Glu Ile Met Thr Asp Thr 
            1060                1065                1070


Glu Lys Ile His Pro Ser Ser Asn Thr Ala Val Ala Lys Val Arg Thr 
        1075                1080                1085


Ser Ser Ser Val His Glu Ser His Ser Ser Val Leu Ala Asp Ser Glu 
    1090                1095                1100


Thr Thr Ile Thr Ile Pro Ser Met Gly Ile Thr Ser Ala Val Asp Asp 
1105                1110                1115                1120


Thr Thr Val Phe Thr Ser Asn Pro Ala Phe Ser Glu Thr Arg Arg Ile 
                1125                1130                1135


Pro Thr Glu Pro Thr Phe Ser Leu Thr Pro Gly Phe Arg Glu Thr Ser 
            1140                1145                1150


Thr Ser Glu Glu Thr Thr Ser Ile Thr Glu Thr Ser Ala Val Leu Tyr 
        1155                1160                1165


Gly Val Pro Thr Ser Ala Thr Thr Glu Val Ser Met Thr Glu Ile Met 
    1170                1175                1180


Ser Ser Asn Arg Ile His Ile Pro Asp Ser Asp Gln Ser Thr Met Ser 
1185                1190                1195                1200


Pro Asp Ile Ile Thr Glu Val Ile Thr Arg Leu Ser Ser Ser Ser Met 
                1205                1210                1215


Met Ser Glu Ser Thr Gln Met Thr Ile Thr Thr Gln Lys Ser Ser Pro 
            1220                1225                1230


Gly Ala Thr Ala Gln Ser Thr Leu Thr Leu Ala Thr Thr Thr Ala Pro 
        1235                1240                1245


Leu Ala Arg Thr His Ser Thr Val Pro Pro Arg Phe Leu His Ser Glu 
    1250                1255                1260


Met Thr Thr Leu Met Ser Arg Ser Pro Glu Asn Pro Ser Trp Lys Ser 
1265                1270                1275                1280


Ser Leu Phe Val Glu Lys Thr Ser Ser Ser Ser Ser Leu Leu Ser Leu 
                1285                1290                1295


Pro Val Thr Thr Ser Pro Ser Val Ser Ser Thr Leu Pro Gln Ser Ile 
            1300                1305                1310


Pro Ser Ser Ser Phe Ser Val Thr Ser Leu Leu Thr Pro Gly Met Val 
        1315                1320                1325


Lys Thr Thr Asp Thr Ser Thr Glu Pro Gly Thr Ser Leu Ser Pro Asn 
    1330                1335                1340


Leu Ser Gly Thr Ser Val Glu Ile Leu Ala Ala Ser Glu Val Thr Thr 
1345                1350                1355                1360


Asp Thr Glu Lys Ile His Pro Ser Ser Ser Met Ala Val Thr Asn Val 
                1365                1370                1375


Gly Thr Thr Ser Ser Gly His Glu Leu Tyr Ser Ser Val Ser Ile His 
            1380                1385                1390


Ser Glu Pro Ser Lys Ala Thr Tyr Pro Val Gly Thr Pro Ser Ser Met 
        1395                1400                1405


Ala Glu Thr Ser Ile Ser Thr Ser Met Pro Ala Asn Phe Glu Thr Thr 
    1410                1415                1420


Gly Phe Glu Ala Glu Pro Phe Ser His Leu Thr Ser Gly Phe Arg Lys 
1425                1430                1435                1440


Thr Asn Met Ser Leu Asp Thr Ser Ser Val Thr Pro Thr Asn Thr Pro 
                1445                1450                1455


Ser Ser Pro Gly Ser Thr His Leu Leu Gln Ser Ser Lys Thr Asp Phe 
            1460                1465                1470


Thr Ser Ser Ala Lys Thr Ser Ser Pro Asp Trp Pro Pro Ala Ser Gln 
        1475                1480                1485


Tyr Thr Glu Ile Pro Val Asp Ile Ile Thr Pro Phe Asn Ala Ser Pro 
    1490                1495                1500


Ser Ile Thr Glu Ser Thr Gly Ile Thr Ser Phe Pro Glu Ser Arg Phe 
1505                1510                1515                1520


Thr Met Ser Val Thr Glu Ser Thr His His Leu Ser Thr Asp Leu Leu 
                1525                1530                1535


Pro Ser Ala Glu Thr Ile Ser Thr Gly Thr Val Met Pro Ser Leu Ser 
            1540                1545                1550


Glu Ala Met Thr Ser Phe Ala Thr Thr Gly Val Pro Arg Ala Ile Ser 
        1555                1560                1565


Gly Ser Gly Ser Pro Phe Ser Arg Thr Glu Ser Gly Pro Gly Asp Ala 
    1570                1575                1580


Thr Leu Ser Thr Ile Ala Glu Ser Leu Pro Ser Ser Thr Pro Val Pro 
1585                1590                1595                1600


Phe Ser Ser Ser Thr Phe Thr Thr Thr Asp Ser Ser Thr Ile Pro Ala 
                1605                1610                1615


Leu His Glu Ile Thr Ser Ser Ser Ala Thr Pro Tyr Arg Val Asp Thr 
            1620                1625                1630


Ser Leu Gly Thr Glu Ser Ser Thr Thr Glu Gly Arg Leu Val Met Val 
        1635                1640                1645


Ser Thr Leu Asp Thr Ser Ser Gln Pro Gly Arg Thr Ser Ser Ser Pro 
    1650                1655                1660


Ile Leu Asp Thr Arg Met Thr Glu Ser Val Glu Leu Gly Thr Val Thr 
1665                1670                1675                1680


Ser Ala Tyr Gln Val Pro Ser Leu Ser Thr Arg Leu Thr Arg Thr Asp 
                1685                1690                1695


Gly Ile Met Glu His Ile Thr Lys Ile Pro Asn Glu Ala Ala His Arg 
            1700                1705                1710


Gly Thr Ile Arg Pro Val Lys Gly Pro Gln Thr Ser Thr Ser Pro Ala 
        1715                1720                1725


Ser Pro Lys Gly Leu His Thr Gly Gly Thr Lys Arg Met Glu Thr Thr 
    1730                1735                1740


Thr Thr Ala Leu Lys Thr Thr Thr Thr Ala Leu Lys Thr Thr Ser Arg 
1745                1750                1755                1760


Ala Thr Leu Thr Thr Ser Val Tyr Thr Pro Thr Leu Gly Thr Leu Thr 
                1765                1770                1775


Pro Leu Asn Ala Ser Met Gln Met Ala Ser Thr Ile Pro Thr Glu Met 
            1780                1785                1790


Met Ile Thr Thr Pro Tyr Val Phe Pro Asp Val Pro Glu Thr Thr Ser 
        1795                1800                1805


Ser Leu Ala Thr Ser Leu Gly Ala Glu Thr Ser Thr Ala Leu Pro Arg 
    1810                1815                1820


Thr Thr Pro Ser Val Phe Asn Arg Glu Ser Glu Thr Thr Ala Ser Leu 
1825                1830                1835                1840


Val Ser Arg Ser Gly Ala Glu Arg Ser Pro Val Ile Gln Thr Leu Asp 
                1845                1850                1855


Val Ser Ser Ser Glu Pro Asp Thr Thr Ala Ser Trp Val Ile His Pro 
            1860                1865                1870


Ala Glu Thr Ile Pro Thr Val Ser Lys Thr Thr Pro Asn Phe Phe His 
        1875                1880                1885


Ser Glu Leu Asp Thr Val Ser Ser Thr Ala Thr Ser His Gly Ala Asp 
    1890                1895                1900


Val Ser Ser Ala Ile Pro Thr Asn Ile Ser Pro Ser Glu Leu Asp Ala 
1905                1910                1915                1920


Leu Thr Pro Leu Val Thr Ile Ser Gly Thr Asp Thr Ser Thr Thr Phe 
                1925                1930                1935


Pro Thr Leu Thr Lys Ser Pro His Glu Thr Glu Thr Arg Thr Thr Trp 
            1940                1945                1950


Leu Thr His Pro Ala Glu Thr Ser Ser Thr Ile Pro Arg Thr Ile Pro 
        1955                1960                1965


Asn Phe Ser His His Glu Ser Asp Ala Thr Pro Ser Ile Ala Thr Ser 
    1970                1975                1980


Pro Gly Ala Glu Thr Ser Ser Ala Ile Pro Ile Met Thr Val Ser Pro 
1985                1990                1995                2000


Gly Ala Glu Asp Leu Val Thr Ser Gln Val Thr Ser Ser Gly Thr Asp 
                2005                2010                2015


Arg Asn Met Thr Ile Pro Thr Leu Thr Leu Ser Pro Gly Glu Pro Lys 
            2020                2025                2030


Thr Ile Ala Ser Leu Val Thr His Pro Glu Ala Gln Thr Ser Ser Ala 
        2035                2040                2045


Ile Pro Thr Ser Thr Ile Ser Pro Ala Val Ser Arg Leu Val Thr Ser 
    2050                2055                2060


Met Val Thr Ser Leu Ala Ala Lys Thr Ser Thr Thr Asn Arg Ala Leu 
2065                2070                2075                2080


Thr Asn Ser Pro Gly Glu Pro Ala Thr Thr Val Ser Leu Val Thr His 
                2085                2090                2095


Pro Ala Gln Thr Ser Pro Thr Val Pro Trp Thr Thr Ser Ile Phe Phe 
            2100                2105                2110


His Ser Lys Ser Asp Thr Thr Pro Ser Met Thr Thr Ser His Gly Ala 
        2115                2120                2125


Glu Ser Ser Ser Ala Val Pro Thr Pro Thr Val Ser Thr Glu Val Pro 
    2130                2135                2140


Gly Val Val Thr Pro Leu Val Thr Ser Ser Arg Ala Val Ile Ser Thr 
2145                2150                2155                2160


Thr Ile Pro Ile Leu Thr Leu Ser Pro Gly Glu Pro Glu Thr Thr Pro 
                2165                2170                2175


Ser Met Ala Thr Ser His Gly Glu Glu Ala Ser Ser Ala Ile Pro Thr 
            2180                2185                2190


Pro Thr Val Ser Pro Gly Val Pro Gly Val Val Thr Ser Leu Val Thr 
        2195                2200                2205


Ser Ser Arg Ala Val Thr Ser Thr Thr Ile Pro Ile Leu Thr Phe Ser 
    2210                2215                2220


Leu Gly Glu Pro Glu Thr Thr Pro Ser Met Ala Thr Ser His Gly Thr 
2225                2230                2235                2240


Glu Ala Gly Ser Ala Val Pro Thr Val Leu Pro Glu Val Pro Gly Met 
                2245                2250                2255


Val Thr Ser Leu Val Ala Ser Ser Arg Ala Val Thr Ser Thr Thr Leu 
            2260                2265                2270


Pro Thr Leu Thr Leu Ser Pro Gly Glu Pro Glu Thr Thr Pro Ser Met 
        2275                2280                2285


Ala Thr Ser His Gly Ala Glu Ala Ser Ser Thr Val Pro Thr Val Ser 
    2290                2295                2300


Pro Glu Val Pro Gly Val Val Thr Ser Leu Val Thr Ser Ser Ser Gly 
2305                2310                2315                2320


Val Asn Ser Thr Ser Ile Pro Thr Leu Ile Leu Ser Pro Gly Glu Leu 
                2325                2330                2335


Glu Thr Thr Pro Ser Met Ala Thr Ser His Gly Ala Glu Ala Ser Ser 
            2340                2345                2350


Ala Val Pro Thr Pro Thr Val Ser Pro Gly Val Ser Gly Val Val Thr 
        2355                2360                2365


Pro Leu Val Thr Ser Ser Arg Ala Val Thr Ser Thr Thr Ile Pro Ile 
    2370                2375                2380


Leu Thr Leu Ser Ser Ser Glu Pro Glu Thr Thr Pro Ser Met Ala Thr 
2385                2390                2395                2400


Ser His Gly Val Glu Ala Ser Ser Ala Val Leu Thr Val Ser Pro Glu 
                2405                2410                2415


Val Pro Gly Met Val Thr Ser Leu Val Thr Ser Ser Arg Ala Val Thr 
            2420                2425                2430


Ser Thr Thr Ile Pro Thr Leu Thr Ile Ser Ser Asp Glu Pro Glu Thr 
        2435                2440                2445


Thr Thr Ser Leu Val Thr His Ser Glu Ala Lys Met Ile Ser Ala Ile 
    2450                2455                2460


Pro Thr Leu Ala Val Ser Pro Thr Val Gln Gly Leu Val Thr Ser Leu 
2465                2470                2475                2480


Val Thr Ser Ser Gly Ser Glu Thr Ser Ala Phe Ser Asn Leu Thr Val 
                2485                2490                2495


Ala Ser Ser Gln Pro Glu Thr Ile Asp Ser Trp Val Ala His Pro Gly 
            2500                2505                2510


Thr Glu Ala Ser Ser Val Val Pro Thr Leu Thr Val Ser Thr Gly Glu 
        2515                2520                2525


Pro Phe Thr Asn Ile Ser Leu Val Thr His Pro Ala Glu Ser Ser Ser 
    2530                2535                2540


Thr Leu Pro Arg Thr Thr Ser Arg Phe Ser His Ser Glu Leu Asp Thr 
2545                2550                2555                2560


Met Pro Ser Thr Val Thr Ser Pro Glu Ala Glu Ser Ser Ser Ala Ile 
                2565                2570                2575


Ser Thr Thr Ile Ser Pro Gly Ile Pro Gly Val Leu Thr Ser Leu Val 
            2580                2585                2590


Thr Ser Ser Gly Arg Asp Ile Ser Ala Thr Phe Pro Thr Val Pro Glu 
        2595                2600                2605


Ser Pro His Glu Ser Glu Ala Thr Ala Ser Trp Val Thr His Pro Ala 
    2610                2615                2620


Val Thr Ser Thr Thr Val Pro Arg Thr Thr Pro Asn Tyr Ser His Ser 
2625                2630                2635                2640


Glu Pro Asp Thr Thr Pro Ser Ile Ala Thr Ser Pro Gly Ala Glu Ala 
                2645                2650                2655


Thr Ser Asp Phe Pro Thr Ile Thr Val Ser Pro Asp Val Pro Asp Met 
            2660                2665                2670


Val Thr Ser Gln Val Thr Ser Ser Gly Thr Asp Thr Ser Ile Thr Ile 
        2675                2680                2685


Pro Thr Leu Thr Leu Ser Ser Gly Glu Pro Glu Thr Thr Thr Ser Phe 
    2690                2695                2700


Ile Thr Tyr Ser Glu Thr His Thr Ser Ser Ala Ile Pro Thr Leu Pro 
2705                2710                2715                2720


Val Ser Pro Gly Ala Ser Lys Met Leu Thr Ser Leu Val Ile Ser Ser 
                2725                2730                2735


Gly Thr Asp Ser Thr Thr Thr Phe Pro Thr Leu Thr Glu Thr Pro Tyr 
            2740                2745                2750


Glu Pro Glu Thr Thr Ala Ile Gln Leu Ile His Pro Ala Glu Thr Asn 
        2755                2760                2765


Thr Met Val Pro Arg Thr Thr Pro Lys Phe Ser His Ser Lys Ser Asp 
    2770                2775                2780


Thr Thr Leu Pro Val Ala Ile Thr Ser Pro Gly Pro Glu Ala Ser Ser 
2785                2790                2795                2800


Ala Val Ser Thr Thr Thr Ile Ser Pro Asp Met Ser Asp Leu Val Thr 
                2805                2810                2815


Ser Leu Val Pro Ser Ser Gly Thr Asp Thr Ser Thr Thr Phe Pro Thr 
            2820                2825                2830


Leu Ser Glu Thr Pro Tyr Glu Pro Glu Thr Thr Ala Thr Trp Leu Thr 
        2835                2840                2845


His Pro Ala Glu Thr Ser Thr Thr Val Ser Gly Thr Ile Pro Asn Phe 
    2850                2855                2860


Ser His Arg Gly Ser Asp Thr Ala Pro Ser Met Val Thr Ser Pro Gly 
2865                2870                2875                2880


Val Asp Thr Arg Ser Gly Val Pro Thr Thr Thr Ile Pro Pro Ser Ile 
                2885                2890                2895


Pro Gly Val Val Thr Ser Gln Val Thr Ser Ser Ala Thr Asp Thr Ser 
            2900                2905                2910


Thr Ala Ile Pro Thr Leu Thr Pro Ser Pro Gly Glu Pro Glu Thr Thr 
        2915                2920                2925


Ala Ser Ser Ala Thr His Pro Gly Thr Gln Thr Gly Phe Thr Val Pro 
    2930                2935                2940


Ile Arg Thr Val Pro Ser Ser Glu Pro Asp Thr Met Ala Ser Trp Val 
2945                2950                2955                2960


Thr His Pro Pro Gln Thr Ser Thr Pro Val Ser Arg Thr Thr Ser Ser 
                2965                2970                2975


Phe Ser His Ser Ser Pro Asp Ala Thr Pro Val Met Ala Thr Ser Pro 
            2980                2985                2990


Arg Thr Glu Ala Ser Ser Ala Val Leu Thr Thr Ile Ser Pro Gly Ala 
        2995                3000                3005


Pro Glu Met Val Thr Ser Gln Ile Thr Ser Ser Gly Ala Ala Thr Ser 
    3010                3015                3020


Thr Thr Val Pro Thr Leu Thr His Ser Pro Gly Met Pro Glu Thr Thr 
3025                3030                3035                3040


Ala Leu Leu Ser Thr His Pro Arg Thr Glu Thr Ser Lys Thr Phe Pro 
                3045                3050                3055


Ala Ser Thr Val Phe Pro Gln Val Ser Glu Thr Thr Ala Ser Leu Thr 
            3060                3065                3070


Ile Arg Pro Gly Ala Glu Thr Ser Thr Ala Leu Pro Thr Gln Thr Thr 
        3075                3080                3085


Ser Ser Leu Phe Thr Leu Leu Val Thr Gly Thr Ser Arg Val Asp Leu 
    3090                3095                3100


Ser Pro Thr Ala Ser Pro Gly Val Ser Ala Lys Thr Ala Pro Leu Ser 
3105                3110                3115                3120


Thr His Pro Gly Thr Glu Thr Ser Thr Met Ile Pro Thr Ser Thr Leu 
                3125                3130                3135


Ser Leu Gly Leu Leu Glu Thr Thr Gly Leu Leu Ala Thr Ser Ser Ser 
            3140                3145                3150


Ala Glu Thr Ser Thr Ser Thr Leu Thr Leu Thr Val Ser Pro Ala Val 
        3155                3160                3165


Ser Gly Leu Ser Ser Ala Ser Ile Thr Thr Asp Lys Pro Gln Thr Val 
    3170                3175                3180


Thr Ser Trp Asn Thr Glu Thr Ser Pro Ser Val Thr Ser Val Gly Pro 
3185                3190                3195                3200


Pro Glu Phe Ser Arg Thr Val Thr Gly Thr Thr Met Thr Leu Ile Pro 
                3205                3210                3215


Ser Glu Met Pro Thr Pro Pro Lys Thr Ser His Gly Glu Gly Val Ser 
            3220                3225                3230


Pro Thr Thr Ile Leu Arg Thr Thr Met Val Glu Ala Thr Asn Leu Ala 
        3235                3240                3245


Thr Thr Gly Ser Ser Pro Thr Val Ala Lys Thr Thr Thr Thr Phe Asn 
    3250                3255                3260


Thr Leu Ala Gly Ser Leu Phe Thr Pro Leu Thr Thr Pro Gly Met Ser 
3265                3270                3275                3280


Thr Leu Ala Ser Glu Ser Val Thr Ser Arg Thr Ser Tyr Asn His Arg 
                3285                3290                3295


Ser Trp Ile Ser Thr Thr Ser Ser Tyr Asn Arg Arg Tyr Trp Thr Pro 
            3300                3305                3310


Ala Thr Ser Thr Pro Val Thr Ser Thr Phe Ser Pro Gly Ile Ser Thr 
        3315                3320                3325


Ser Ser Ile Pro Ser Ser Thr Ala Ala Thr Val Pro Phe Met Val Pro 
    3330                3335                3340


Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met 
3345                3350                3355                3360


Arg His Pro Gly Ser Arg Lys Phe Asn Ala Thr Glu Arg Glu Leu Gln 
                3365                3370                3375


Gly Leu Leu Lys Pro Leu Phe Arg Asn Ser Ser Leu Glu Tyr Leu Tyr 
            3380                3385                3390


Ser Gly Cys Arg Leu Ala Ser Leu Arg Pro Glu Lys Asp Ser Ser Ala 
        3395                3400                3405


Thr Ala Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Glu Asp Leu 
    3410                3415                3420


Gly Leu Asp Arg Glu Arg Leu Tyr Trp Glu Leu Ser Asn Leu Thr Asn 
3425                3430                3435                3440


Gly Ile Gln Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr 
                3445                3450                3455


Val Asn Gly Phe Thr His Arg Ser Ser Met Pro Thr Thr Ser Thr Pro 
            3460                3465                3470


Gly Thr Ser Thr Val Asp Val Gly Thr Ser Gly Thr Pro Ser Ser Ser 
        3475                3480                3485


Pro Ser Pro Thr Thr Ala Gly Pro Leu Leu Met Pro Phe Thr Leu Asn 
    3490                3495                3500


Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met Arg Arg Thr Gly 
3505                3510                3515                3520


Ser Arg Lys Phe Asn Thr Met Glu Ser Val Leu Gln Gly Leu Leu Lys 
                3525                3530                3535


Pro Leu Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg 
            3540                3545                3550


Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Ala Ala Thr Gly Val Asp 
        3555                3560                3565


Ala Ile Cys Thr His Arg Leu Asp Pro Lys Ser Pro Gly Leu Asn Arg 
    3570                3575                3580


Glu Gln Leu Tyr Trp Glu Leu Ser Lys Leu Thr Asn Asp Ile Glu Glu 
3585                3590                3595                3600


Leu Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe 
                3605                3610                3615


Thr His Gln Ser Ser Val Ser Thr Thr Ser Thr Pro Gly Thr Ser Thr 
            3620                3625                3630


Val Asp Leu Arg Thr Ser Gly Thr Pro Ser Ser Leu Ser Ser Pro Thr 
        3635                3640                3645


Ile Met Ala Ala Gly Pro Leu Leu Val Pro Phe Thr Leu Asn Phe Thr 
    3650                3655                3660


Ile Thr Asn Leu Gln Tyr Gly Glu Asp Met Gly His Pro Gly Ser Arg 
3665                3670                3675                3680


Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Gly Pro Ile 
                3685                3690                3695


Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr 
            3700                3705                3710


Ser Leu Arg Ser Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Ala Ile 
        3715                3720                3725


Cys Ile His His Leu Asp Pro Lys Ser Pro Gly Leu Asn Arg Glu Arg 
    3730                3735                3740


Leu Tyr Trp Glu Leu Ser Gln Leu Thr Asn Gly Ile Lys Glu Leu Gly 
3745                3750                3755                3760


Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe Thr His 
                3765                3770                3775


Arg Thr Ser Val Pro Thr Ser Ser Thr Pro Gly Thr Ser Thr Val Asp 
            3780                3785                3790


Leu Gly Thr Ser Gly Thr Pro Phe Ser Leu Pro Ser Pro Ala Thr Ala 
        3795                3800                3805


Gly Pro Leu Leu Val Leu Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu 
    3810                3815                3820


Lys Tyr Glu Glu Asp Met His Arg Pro Gly Ser Arg Lys Phe Asn Thr 
3825                3830                3835                3840


Thr Glu Arg Val Leu Gln Thr Leu Leu Gly Pro Met Phe Lys Asn Thr 
                3845                3850                3855


Ser Val Gly Leu Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Ser 
            3860                3865                3870


Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Ala Ile Cys Thr His Arg 
        3875                3880                3885


Leu Asp Pro Lys Ser Pro Gly Val Asp Arg Glu Gln Leu Tyr Trp Glu 
    3890                3895                3900


Leu Ser Gln Leu Thr Asn Gly Ile Lys Glu Leu Gly Pro Tyr Thr Leu 
3905                3910                3915                3920


Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe Thr His Trp Ile Pro Val 
                3925                3930                3935


Pro Thr Ser Ser Thr Pro Gly Thr Ser Thr Val Asp Leu Gly Ser Gly 
            3940                3945                3950


Thr Pro Ser Ser Leu Pro Ser Pro Thr Thr Ala Gly Pro Leu Leu Val 
        3955                3960                3965


Pro Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Lys Tyr Glu Glu Asp 
    3970                3975                3980


Met His Cys Pro Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu 
3985                3990                3995                4000


Gln Ser Leu Leu Gly Pro Met Phe Lys Asn Thr Ser Val Gly Pro Leu 
                4005                4010                4015


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Ser Glu Lys Asp Gly Ala 
            4020                4025                4030


Ala Thr Gly Val Asp Ala Ile Cys Thr His Arg Leu Asp Pro Lys Ser 
        4035                4040                4045


Pro Gly Val Asp Arg Glu Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr 
    4050                4055                4060


Asn Gly Ile Lys Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu 
4065                4070                4075                4080


Tyr Val Asn Gly Phe Thr His Gln Thr Ser Ala Pro Asn Thr Ser Thr 
                4085                4090                4095


Pro Gly Thr Ser Thr Val Asp Leu Gly Thr Ser Gly Thr Pro Ser Ser 
            4100                4105                4110


Leu Pro Ser Pro Thr Ser Ala Gly Pro Leu Leu Val Pro Phe Thr Leu 
        4115                4120                4125


Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp Met His His Pro 
    4130                4135                4140


Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu 
4145                4150                4155                4160


Gly Pro Met Phe Lys Asn Thr Ser Val Gly Leu Leu Tyr Ser Gly Cys 
                4165                4170                4175


Arg Leu Thr Leu Leu Arg Pro Glu Lys Asn Gly Ala Ala Thr Gly Met 
            4180                4185                4190


Asp Ala Ile Cys Ser His Arg Leu Asp Pro Lys Ser Pro Gly Leu Asn 
        4195                4200                4205


Arg Glu Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr His Gly Ile Lys 
    4210                4215                4220


Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly 
4225                4230                4235                4240


Phe Thr His Arg Ser Ser Val Ala Pro Thr Ser Thr Pro Gly Thr Ser 
                4245                4250                4255


Thr Val Asp Leu Gly Thr Ser Gly Thr Pro Ser Ser Leu Pro Ser Pro 
            4260                4265                4270


Thr Thr Ala Val Pro Leu Leu Val Pro Phe Thr Leu Asn Phe Thr Ile 
        4275                4280                4285


Thr Asn Leu Gln Tyr Gly Glu Asp Met Arg His Pro Gly Ser Arg Lys 
    4290                4295                4300


Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Gly Pro Leu Phe 
4305                4310                4315                4320


Lys Asn Ser Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Ile Ser 
                4325                4330                4335


Leu Arg Ser Glu Lys Asp Gly Ala Ala Thr Gly Val Asp Ala Ile Cys 
            4340                4345                4350


Thr His His Leu Asn Pro Gln Ser Pro Gly Leu Asp Arg Glu Gln Leu 
        4355                4360                4365


Tyr Trp Gln Leu Ser Gln Met Thr Asn Gly Ile Lys Glu Leu Gly Pro 
    4370                4375                4380


Tyr Thr Leu Asp Arg Asn Ser Leu Tyr Val Asn Gly Phe Thr His Arg 
4385                4390                4395                4400


Ser Ser Gly Leu Thr Thr Ser Thr Pro Trp Thr Ser Thr Val Asp Leu 
                4405                4410                4415


Gly Thr Ser Gly Thr Pro Ser Pro Val Pro Ser Pro Thr Thr Thr Gly 
            4420                4425                4430


Pro Leu Leu Val Pro Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Gln 
        4435                4440                4445


Tyr Glu Glu Asn Met Gly His Pro Gly Ser Arg Lys Phe Asn Ile Thr 
    4450                4455                4460


Glu Ser Val Leu Gln Gly Leu Leu Lys Pro Leu Phe Lys Ser Thr Ser 
4465                4470                4475                4480


Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu 
                4485                4490                4495


Lys Asp Gly Val Ala Thr Arg Val Asp Ala Ile Cys Thr His Arg Pro 
            4500                4505                4510


Asp Pro Lys Ile Pro Gly Leu Asp Arg Gln Gln Leu Tyr Trp Glu Leu 
        4515                4520                4525


Ser Gln Leu Thr His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp 
    4530                4535                4540


Arg Asp Ser Leu Tyr Val Asn Gly Phe Thr Gln Arg Ser Ser Val Pro 
4545                4550                4555                4560


Thr Thr Ser Thr Pro Gly Thr Phe Thr Val Gln Pro Glu Thr Ser Glu 
                4565                4570                4575


Thr Pro Ser Ser Leu Pro Gly Pro Thr Ala Thr Gly Pro Val Leu Leu 
            4580                4585                4590


Pro Phe Thr Leu Asn Phe Thr Ile Thr Asn Leu Gln Tyr Glu Glu Asp 
        4595                4600                4605


Met Arg Arg Pro Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu 
    4610                4615                4620


Gln Gly Leu Leu Met Pro Leu Phe Lys Asn Thr Ser Val Ser Ser Leu 
4625                4630                4635                4640


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Ala 
                4645                4650                4655


Ala Thr Arg Val Asp Ala Val Cys Thr His Arg Pro Asp Pro Lys Ser 
            4660                4665                4670


Pro Gly Leu Asp Arg Glu Arg Leu Tyr Trp Lys Leu Ser Gln Leu Thr 
        4675                4680                4685


His Gly Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg His Ser Leu 
    4690                4695                4700


Tyr Val Asn Gly Phe Thr His Gln Ser Ser Met Thr Thr Thr Arg Thr 
4705                4710                4715                4720


Pro Asp Thr Ser Thr Met His Leu Ala Thr Ser Arg Thr Pro Ala Ser 
                4725                4730                4735


Leu Ser Gly Pro Met Thr Ala Ser Pro Leu Leu Val Leu Phe Thr Ile 
            4740                4745                4750


Asn Phe Thr Ile Thr Asn Leu Arg Tyr Glu Glu Asn Met His His Pro 
        4755                4760                4765


Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu 
    4770                4775                4780


Arg Pro Val Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys 
4785                4790                4795                4800


Arg Leu Thr Leu Leu Arg Pro Lys Lys Asp Gly Ala Ala Thr Lys Val 
                4805                4810                4815


Asp Ala Ile Cys Thr Tyr Arg Pro Asp Pro Lys Ser Pro Gly Leu Asp 
            4820                4825                4830


Arg Glu Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr His Ser Ile Thr 
        4835                4840                4845


Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu Tyr Val Asn Gly 
    4850                4855                4860


Phe Thr Gln Arg Ser Ser Val Pro Thr Thr Ser Ile Pro Gly Thr Pro 
4865                4870                4875                4880


Thr Val Asp Leu Gly Thr Ser Gly Thr Pro Val Ser Lys Pro Gly Pro 
                4885                4890                4895


Ser Ala Ala Ser Pro Leu Leu Val Leu Phe Thr Leu Asn Phe Thr Ile 
            4900                4905                4910


Thr Asn Leu Arg Tyr Glu Glu Asn Met Gln His Pro Gly Ser Arg Lys 
        4915                4920                4925


Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu Arg Ser Leu Phe 
    4930                4935                4940


Lys Ser Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys Arg Leu Thr Leu 
4945                4950                4955                4960


Leu Arg Pro Glu Lys Asp Gly Thr Ala Thr Gly Val Asp Ala Ile Cys 
                4965                4970                4975


Thr His His Pro Asp Pro Lys Ser Pro Arg Leu Asp Arg Glu Gln Leu 
            4980                4985                4990


Tyr Trp Glu Leu Ser Gln Leu Thr His Asn Ile Thr Glu Leu Gly Pro 
        4995                5000                5005


Tyr Ala Leu Asp Asn Asp Ser Leu Phe Val Asn Gly Phe Thr His Arg 
    5010                5015                5020


Ser Ser Val Ser Thr Thr Ser Thr Pro Gly Thr Pro Thr Val Phe Thr 
5025                5030                5035                5040


Leu Asn Phe Thr Ile Thr Asn Leu Arg Tyr Glu Glu Asn Met Trp Pro 
                5045                5050                5055


Gly Ser Arg Lys Phe Asn Thr Thr Glu Arg Val Leu Gln Gly Leu Leu 
            5060                5065                5070


Arg Pro Leu Phe Lys Asn Thr Ser Val Gly Pro Leu Tyr Ser Gly Cys 
        5075                5080                5085


Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Glu Ala Thr Gly Val 
    5090                5095                5100


Asp Ala Ile Cys Thr His Arg Pro Asp Pro Thr Gly Pro Gly Leu Asp 
5105                5110                5115                5120


Arg Glu Gln Leu Tyr Leu Glu Leu Ser Gln Leu Thr His Ser Ile Thr 
                5125                5130                5135


Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu Tyr Val Asn Gly 
            5140                5145                5150


Arg Gly Gly Gln Arg Gly Ala Ile His Thr Glu Leu His His Gln Gln 
        5155                5160                5165


Pro Ala Leu His Gly Gly His Gly Pro Thr Arg Leu Pro Gln Val Gln 
    5170                5175                5180


His His Arg Gln Arg His Ala Ala Pro Ala Gln Ser Phe Val Pro Glu 
5185                5190                5195                5200


Glu Gln Pro Gly Cys Thr Val His Arg Leu Gln Gly His Arg Thr Lys 
                5205                5210                5215


Val Cys Glu Glu Arg Cys 
            5220


<210>  9098
<211>  40713
<212>  DNA
<213>  Homo sapiens

<400>  9098
cagagactag tcccagattc aagacagggt taccttcagc aacaaccact gtttcaacct     60

ctgccacttc tctctctgct actgtaatgg tctctaaatt cacttctcca gcaactagtt    120

ccatggaagc aacttctatc agggaaccat caacaaccat cctcacaaca gagaccacga    180

atggcccagg ctctatggct gtggcttcta ccaacatccc aattggaaag ggctacatta    240

ctgaaggaag attggacaca agccatctgc ccattggaac cacagcttcc tctgagacat    300

ctatggattt taccatggcc aaagaaagtg tctcaatgtc agtatctcca tctcagtcca    360

tggatgctgc tggctcaagc actccaggaa ggacaagcca attcgttgac acattttctg    420

atgatgtcta tcatttaaca tccagagaaa ttacaatacc tagagatgga acaagctcag    480

ctctgactcc acaaatgact gcaactcacc ctccatctcc tgatcctggc tctgctagaa    540

gcacctggct tggcatcttg tcctcatctc cttcttctcc tactcccaaa gtcacaatga    600

gctccacatt ttcaactcag agagtcacca caagcatgat aatggacaca gttgaaacta    660

gtcggtggaa catgcccaac ttaccttcca cgacttcctt gacaccaagt aatattccaa    720

caagtggtgc cataggaaaa agcaccctgg ttcccttgga cactccatct ccagccacat    780

cattggaggc atcagaaggg ggacttccaa ccctcagcac ctaccctgaa tcaacaaaca    840

cacccagcat ccacctcgga gcacacgcta gttcagaaag tccaagcacc atcaaactta    900

ccatggcttc agtagtaaaa cctggctctt acacacctct caccttcccc tcaatagaga    960

cccacattca tgtatcaaca gccagaatgg cttactcttc tgggtcttca cctgagatga   1020

cagctcctgg agagactaac actggtagta cctgggaccc caccacctac atcaccacta   1080

cggatcctaa ggatacaagt tcagctcagg tctctacacc ccactcagtg aggacactca   1140

gaaccacaga aaaccatcca aagacagagt ccgccacccc agctgcttac tctggaagtc   1200

ctaaaatctc aagttcaccc aatctcacca gtccggccac aaaagcatgg accatcacag   1260

acacaactga acactccact caattacatt acacaaaatt ggcagaaaaa tcatctggat   1320

ttgagacaca gtcagctcca ggacctgtct ctgtagtaat ccctacctcc cctaccattg   1380

gaagcagcac attggaacta acttctgatg tcccagggga acccctggtc cttgctccca   1440

gtgagcagac cacaatcact ctccccatgg caacatggct gagtaccagt ttgacagagg   1500

aaatggcttc aacagacctt gatatttcaa gtccaagttc acccatgagt acatttgcta   1560

tttttccacc tatgtccaca ccttctcatg aactttcaaa gtcagaggca gataccagtg   1620

ccattagaaa tacagattca acaacgttgg atcagcacct aggaatcagg agtttgggca   1680

gaactgggga cttaacaact gttcctatca ccccactgac aaccacgtgg accagtgtga   1740

ttgaacactc aacacaagca caggacaccc tttctgcaac gatgagtcct actcacgtga   1800

cacagtcact caaagatcaa acatctatac cagcctcagc atccccttcc catcttactg   1860

aagtctaccc tgagctcggg acacaaggga gaagctcctc tgaggcaacc actttttgga   1920

aaccatctac agacacactg tccagagaga ttgagactgg cccaacaaac attcaatcca   1980

ctccacccat ggacaacaca acaacaggga gcagtagtag tggagtcacc ctgggcatag   2040

cccaccttcc cataggaaca tcctccccag ctgagacatc cacaaacatg gcactggaaa   2100

gaagaagttc tacagccact gtctctatgg ctgggacaat gggactcctt gttactagtg   2160

ctccaggaag aagcatcagc cagtcattag gaagagtttc ctctgtcctt tctgagtcaa   2220

ctactgaagg agtcacagat tctagtaagg gaagcagccc aaggctgaac acacagggaa   2280

atacagctct ctcctcctct cttgaaccca gctatgctga aggaagccag atgagcacaa   2340

gcatccctct aacctcatct cctacaactc ctgatgtgga attcataggg ggcagcacat   2400

tttggaccaa ggaggtcacc acagttatga cctcagacat ctccaagtct tcagcaagga   2460

cagagtccag ctcagctacc cttatgtcca cagctttggg aagcactgaa aatacaggaa   2520

aagaaaaact cagaactgcc tctatggatc ttccatctcc aactccatca atggaggtga   2580

caccatggat ttctctcact ctcagtaatg cccccaatac cacagattca cttgacctca   2640

gccatggggt gcacaccagc tctgcaggga ctttggccac tgacaggtca ttgaatactg   2700

gtgtcactag agcctccaga ttggaaaacg gctctgatac ctcttctaag tccctgtcta   2760

tgggaaacag cactcacact tccatgactt acacagagaa gagtgaagtg tcttcttcaa   2820

tccatccccg acctgagacc tcagctcctg gagcagagac cactttgact tccactcctg   2880

gaaacagggc cataagctta acattgcctt tttcatccat tccagtggaa gaagtcattt   2940

ctacaggcat aacctcagga ccagacatca actcagcacc catgacacat tctcccatca   3000

ccccaccaac aattgtatgg accagtacag gcacaattga acagtccact caaccactac   3060

atgcagtttc ttcagaaaaa gtttctgtgc agacacagtc aactccatat gtcaactctg   3120

tggcagtgtc tgcttcccct acccatgaga attcagtctc ttctggaagc agcacatcct   3180

ctccatattc ctcagcctca cttgaatcct tggattccac aatcagtagg aggaatgcaa   3240

tcacttcctg gctatgggac ctcactacat ctctccccac tacaacttgg ccaagtacta   3300

gtttatctga ggcactgtcc tcaggccatt ctggggtttc aaacccaagt tcaactacga   3360

ctgaatttcc actcttttca gctgcatcca catctgctgc taagcaaaga aatccagaaa   3420

cagagaccca tggtccccag aatacagccg cgagtacttt gaacactgat gcatcctcgg   3480

tcacaggtct ttctgagact cctgtggggg caagtatcag ctctgaagtc cctcttccaa   3540

tggccataac ttctagatca gatgtttctg gccttacatc tgagagtact gctaacccga   3600

gtttaggcac agcctcttca gcagggacca aattaactag gacaatatcc ctgcccactt   3660

cagagtcttt ggtttccttt agaatgaaca aggatccatg gacagtgtca atccctttgg   3720

ggtcccatcc aactactaat acagaaacaa gcatcccagt aaacagcgca ggtccacctg   3780

gcttgtccac agtagcatca gatgtaattg acacaccttc agatggggct gagagtattc   3840

ccactgtctc cttttccccc tcccctgata ctgaagtgac aactatctca catttcccag   3900

aaaagacaac tcattcattt agaaccattt catctctcac tcatgagttg acttcaagag   3960

tgacacctat tcctggggat tggatgagtt cagctatgtc tacaaagccc acaggagcca   4020

gtccctccat tacactggga gagagaagga caatcacctc tgctgctcca accacttccc   4080

ccatagttct cactgctagt ttcacagaga ccagcacagt ttcactggat aatgaaacta   4140

cagtaaaaac ctcagatatc cttgacgcac ggaaaacaaa tgagctcccc tcagatagca   4200

gttcttcttc tgatctgatc aacacctcca tagcttcttc aactatggat gtcactaaaa   4260

cagcctccat cagtcccact agcatctcag gaatgacagc aagttcctcc ccatctctct   4320

tctcttcaga tagaccccag gttcccacat ctacaacaga gacaaataca gccacctctc   4380

catctgtttc cagtaacacc tattctcttg atgggggctc caatgtgggt ggcactccat   4440

ccactttacc accctttaca atcacccacc ctgtcgagac aagctcggcc ctattagcct   4500

ggtctagacc agtaagaact ttcagcacca tggtcagcac tgacactgcc tccggagaaa   4560

atcctacctc tagcaattct gtggtgactt ctgttccagc accaggtaca tggaccagtg   4620

taggcagtac tactgactta cctgccatgg gctttctcaa gacaagtcct gcaggagagg   4680

cacactcact tctagcatca actattgaac cagccactgc cttcactccc catctctcag   4740

cagcagtggt cactggatcc agtgctacat cagaagccag tcttctcact acgagtgaaa   4800

gcaaagccat tcattcttca ccacagaccc caactacacc cacctctgga gcaaactggg   4860

aaacttcagc tactcctgag agccttttgg tagtcactga gacttcagac acaacactta   4920

cctcaaagat tttggtcaca gataccatct tgttttcaac tgtgtccacg ccaccttcta   4980

aatttccaag tacggggact ctgtctggag cttccttccc tactttactc ccggacactc   5040

cagccatccc tctcactgcc actgagccaa caagttcatt agctacatcc tttgattcca   5100

ccccactggt gactatagct tcggatagtc ttggcacagt cccagagact accctgacca   5160

tgtcagagac ctcaaatggt gatgcactgg ttcttaagac agtaagtaac ccagatagga   5220

gcatccctgg aatcactatc caaggagtaa cagaaagtcc actccatcct tcttccactt   5280

ccccctctaa gattgttgct ccacggaata caacctatga aggttcgatc acagtggcac   5340

tttctacttt gcctgcggga actactggtt cccttgtatt cagtcagagt tctgaaaact   5400

cagagacaac ggctttggta gactcatcag ctgggcttga gagggcatct gtgatgccac   5460

taaccacagg aagccagggt atggctagct ctggaggaat cagaagtggg tccactcact   5520

caactggaac caaaacattt tcttctctcc ctctgaccat gaacccaggt gaggttacag   5580

ccatgtctga aatcaccacg aacagactga cagctactca atcaacagca cccaaaggga   5640

tacctgtgaa gcccaccagt gctgagtcag gcctcctaac acctgtctct gcctcctcaa   5700

gcccatcaaa ggcctttgcc tcactgacta cagctccccc aacttggggg atcccacagt   5760

ctaccttgac atttgagttt tctgaggtcc caagtttgga tactaagtcc gcttctttac   5820

caactcctgg acagtccctg aacaccattc cagactcaga tgcaagcaca gcatcttcct   5880

cactgtccaa gtctccagaa aaaaacccaa gggcaaggat gatgacttcc acaaaggcca   5940

taagtgcaag ctcatttcaa tcaacaggtt ttactgaaac ccctgaggga tctgcctccc   6000

cttctatggc agggcatgaa cccagagtcc ccacttcagg aacaggggac cctagatatg   6060

cctcagagag catgtcttat ccagacccaa gcaaggcatc atcagctatg acatcgacct   6120

ctcttgcatc aaaactcaca actctcttca gcacaggtca agcagcaagg tctggttcta   6180

gttcctctcc cataagccta tccactgaga aagaaacaag cttcctttcc cccactgcat   6240

ccacctccag aaagacttca ctatttcttg ggccttccat ggcaaggcag cccaacatat   6300

tggtgcatct tcagacttca gctctgacac tttctccaac atccactcta aatatgtccc   6360

aggaggagcc tcctgagtta acctcaagcc agaccattgc agaagaagag ggaacaacag   6420

ctgaaacaca gacgttaacc ttcacaccat ctgagacccc aacatccttg ttacctgtct   6480

cttctcccac agaacccaca gccagaagaa agagttctcc agaaacatgg gcaagctcta   6540

tttcagttcc tgccaagacc tccttggttg aaacaactga tggaacgcta gtgaccacca   6600

taaagatgtc aagccaggca gcacaaggaa attccacgtg gcctgcccca gcagaggaga   6660

cggggagcag tccagcaggc acatccccag gaagcccaga aatgtctacc actctcaaaa   6720

tcatgagctc caaggaaccc agcatcagcc cagagatcag gtccactgtg agaaattctc   6780

cttggaagac tccagaaaca actgttccca tggagaccac agtggaacca gtcacccttc   6840

agtccacagc cctaggaagt ggcagcacca gcatctctca cctgcccaca ggaaccacat   6900

caccaaccaa gtcaccaaca gaaaatatgt tggctacaga aagggtctcc ctctccccat   6960

ccccacctga ggcttggacc aacctttatt ctggaactcc aggagggacc aggcagtcac   7020

tggccacaat gtcctctgtc tccctagagt caccaactgc tagaagcatc acagggactg   7080

gtcagcaaag cagtccagaa ctggtttcaa agacaactgg aatggaattc tctatgtggc   7140

atggctctac tggagggacc acaggggaca cacatgtctc tctgagcaca tcttccaata   7200

tccttgaaga ccctgtaacc agcccaaact ctgtgagctc attgacagat aaatccaaac   7260

ataaaaccga gacatgggta agcaccacag ccattccctc cactgtcctg aataataaga   7320

taatggcagc tgaacaacag acaagtcgat ctgtggatga ggcttattca tcaactagtt   7380

cttggtcaga tcagacatct gggagtgaca tcacccttgg tgcatctcct gatgtcacaa   7440

acacattata catcacctcc acagcacaaa ccacctcact agtgtctctg ccctctggag   7500

accaaggcat tacaagcctc accaatccct caggaggaaa aacaagctct gcgtcatctg   7560

tcacatctcc ttcaataggg cttgagactc tgagggccaa tgtaagtgca gtgaaaagtg   7620

acattgcccc tactgctggg catctatctc agacttcatc tcctgcggaa gtgagcatcc   7680

tggacgtaac cacagctcct actccaggta tctccaccac catcaccacc atgggaacca   7740

actcaatctc aactaccaca cccaacccag aagtgggtat gagtaccatg gacagcaccc   7800

cggccacaga gaggcgcaca acttctacag aacacccttc cacctggtct tccacagctg   7860

catcagattc ctggactgtc acagacatga cttcaaactt gaaagttgca agatctcctg   7920

gaacaatttc cacaatgcat acaacttcat tcttagcctc aagcactgaa ttagactcca   7980

tgtctactcc ccatggccgt ataactgtca ttggaaccag cctggtcact ccatcctctg   8040

atgcttcagc tgtaaagaca gagaccagta caagtgaaag aacattgagt ccttcagaca   8100

caactgcatc tactcccatc tcaacttttt ctcgtgtcca gaggatgagc atctcagttc   8160

ctgacatttt aagtacaagt tggactccca gtagtacaga agcagaagat gtgcctgttt   8220

caatggtttc tacagatcat gctagtacaa agactgaccc aaatacgccc ctgtccactt   8280

ttctgtttga ttctctgtcc actcttgact gggacactgg gagatctctg tcatcagcca   8340

cagccactac ctcagctcct cagggggcca caactcccca ggaactcact ttggaaacca   8400

tgatcagccc agctacctca cagttgccct tctctatagg gcacattaca agtgcagtca   8460

caccagctgc aatggcaagg agctctggag ttactttttc aagaccagat cccacaagca   8520

aaaaggcaga gcagacttcc actcagcttc ccaccaccac ttctgcacat ccagggcagg   8580

tgcccagatc agcagcaaca actctggatg tgatcccaca cacagcaaaa actccagatg   8640

caacttttca gagacaaggg cagacagctc ttacaacaga ggcaagagct acatctgact   8700

cctggaatga gaaagaaaaa tcaaccccaa gtgcaccttg gatcactgag atgatgaatt   8760

ctgtctcaga agataccatc aaggaggtta ccagctcctc cagtgtatta aggaccctga   8820

atacgctgga cataaacttg gaatctggga cgacttcatc cccaagttgg aaaagcagcc   8880

catatgagag aattgcccct tctgagtcca ccacagacaa agaggcaatt cacccttcta   8940

caaacacagt agagaccaca ggctgggtca caagttccga acatgcttct cattccacta   9000

tcccagccca ctcagcgtca tccaaactca catctccagt ggttacaacc tccaccaggg   9060

aacaagcaat agtttctatg tcaacaacca catggccaga gtctacaagg gctagaacag   9120

agcctaattc cttcttgact attgaactga gggacgtcag cccttacatg gacaccagct   9180

caaccacaca aacaagtatt atctcttccc caggttccac tgcgatcacc aaggggccta   9240

gaacagaaat tacctcctct aagagaatat ccagctcatt ccttgcccag tctatgaggt   9300

cgtcagacag cccctcagaa gccatcacca ggctgtctaa ctttcctgcc atgacagaat   9360

ctggaggaat gatccttgct atgcaaacaa gtccacctgg cgctacatca ctaagtgcac   9420

ctactttgga tacatcagcc acagcctcct ggacagggac tccactggct acgactcaga   9480

gatttacata ctcagagaag accactctct ttagcaaagg tcctgaggat acatcacagc   9540

caagccctcc ctctgtggaa gaaaccagct cttcctcttc cctggtacct atccatgcta   9600

caacctcgcc ttccaatatt ttgttgacat cacaagggca cagtccctcc tctactccac   9660

ctgtgacctc agttttcttg tctgagacct ctggcctggg gaagaccaca gacatgtcga   9720

ggataagctt ggaacctggc acaagtttac ctcccaattt gagcagtaca gcaggtgagg   9780

cgttatccac ttatgaagcc tccagagata caaaggcaat tcatcattct gcagacacag   9840

cagtgacgaa tatggaggca accagttctg aatattctcc tatcccaggc catacaaagc   9900

catccaaagc cacatctcca ttggttacct cccacatcat gggggacatc acttcttcca   9960

catcagtatt tggctcctcc gagaccacag agattgagac agtgtcctct gtgaaccagg  10020

gacttcagga gagaagcaca tcccaggtgg ccagctctgc tacagagaca agcactgtca  10080

ttacccatgt gtctagtggt gatgctacta ctcatgtcac caagacacaa gccactttct  10140

ctagcggaac atccatctca agccctcatc agtttataac ttctaccaac acatttacag  10200

atgtgagcac caacccctcc acctctctga taatgacaga atcttcagga gtgaccatca  10260

ccacccaaac aggtcctact ggagctgcaa cacagggtcc atatctcttg gacacatcaa  10320

ccatgcctta cttgacagag actccattag ctgtgactcc agattttatg caatcagaga  10380

agaccactct cataagcaaa ggtcccaagg atgtgtcctg gacaagccct ccctctgtgg  10440

cagaaaccag ctatccctct tccctgacac ctttcttggt cacaaccata cctcctgcca  10500

cttccacgtt acaagggcaa catacatcct ctcctgtttc tgcgacttca gttcttacct  10560

ctggactggt gaagaccaca gatatgttga acacaagcat ggaacctgtg accaattcac  10620

ctcaaaattt gaacaatcca tcaaatgaga tactggccac tttggcagcc accacagata  10680

tagagactat tcatccttcc ataaacaaag cagtgaccaa tatggggact gccagttcag  10740

cacatgtact gcattccact ctcccagtca gctcagaacc atctacagcc acatctccaa  10800

tggttcctgc ctccagcatg ggggacgctc ttgcttctat atcaatacct ggttctgaga  10860

ccacagacat tgagggagag ccaacatcct ccctgactgc tggacgaaaa gagaacagca  10920

ccctccagga gatgaactca actacagagt caaacatcat cctctccaat gtgtctgtgg  10980

gggctattac tgaagccaca aaaatggaag tcccctcttt tgatgcaaca ttcataccaa  11040

ctcctgctca gtcaacaaag ttcccagata ttttctcagt agccagcagt agactttcaa  11100

actctcctcc catgacaata tctacccaca tgaccaccac ccagacaggg tcttctggag  11160

ctacatcaaa gattccactt gccttagaca catcaacctt ggaaacctca gcagggactc  11220

catcagtggt gactgagggg tttgcccact caaaaataac cactgcaatg aacaatgatg  11280

tcaaggacgt gtcacagaca aaccctccct ttcaggatga agccagctct ccctcttctc  11340

aagcacctgt ccttgtcaca accttacctt cttctgttgc tttcacaccg caatggcaca  11400

gtacctcctc tcctgtttct atgtcctcag ttcttacttc ttcactggta aagaccgcag  11460

gcaaggtgga tacaagctta gaaacagtga ccagttcacc tcaaagtatg agcaacactt  11520

tggatgacat atcggtcact tcagcagcca ccacagatat agagacaacg catccttcca  11580

taaacacagt agttaccaat gtggggacca ccggttcagc atttgaatca cattctactg  11640

tctcagctta cccagagcca tctaaagtca catctccaaa tgttaccacc tccaccatgg  11700

aagacaccac aatttccaga tcaataccta aatcctctaa gactacaaga actgagactg  11760

agacaacttc ctccctgact cctaaactga gggagaccag catctcccag gagatcacct  11820

cgtccacaga gacaagcact gttccttaca aagagctcac tggtgccact accgaggtat  11880

ccaggacaga tgtcacttcc tctagcagta catccttccc tggccctgat cagtccacag  11940

tgtcactaga catctccaca gaaaccaaca ccaggctgtc tacctcccca ataatgacag  12000

aatctgcaga aataaccatc accacccaaa caggtcctca tggggctaca tcacaggata  12060

cttttaccat ggacccatca aatacaaccc cccaggcagg gatccactca gctatgactc  12120

atggattttc acaattggat gtgaccactc ttatgagcag aattccacag gatgtatcat  12180

ggacaagtcc tccctctgtg gataaaacca gctccccctc ttcctttctg tcctcacctg  12240

caatgaccac accttccctg atttcttcta ccttaccaga ggataagctc tcctctccta  12300

tgacttcact tctcacctct ggcctagtga agattacaga catattacgt acacgcttgg  12360

aacctgtgac cagctcactt ccaaatttca gcagcacctc agataagata ctggccactt  12420

ctaaagacag taaagacaca aaggaaattt ttccttctat aaacacagaa gagaccaatg  12480

tgaaagccaa caactctgga catgaatccc attcccctgc actggctgac tcagagacac  12540

ccaaagccac aactcaaatg gttatcacca ccactgtggg agatccagct ccttccacat  12600

caatgccagt gcatggttcc tctgagacta caaacattaa gagagagcca acatatttct  12660

tgactcctag actgagagag accagtacct ctcaggagtc cagctttccc acggacacaa  12720

gttttctact ttccaaagtc cccactggta ctattactga ggtctccagt acaggggtca  12780

actcttctag caaaatttcc accccagacc atgataagtc cacagtgcca cctgacacct  12840

tcacaggaga gatccccagg gtcttcacct cctctattaa gacaaaatct gcagaaatga  12900

cgatcaccac ccaagcaagt cctcctgagt ctgcatcgca cagtaccctt cccttggaca  12960

catcaaccac actttcccag ggagggactc attcaactgt gactcaggga ttcccatact  13020

cagaggtgac cactctcatg ggcatgggtc ctgggaatgt gtcatggatg acaactcccc  13080

ctgtggaaga aaccagctct gtgtcttccc tgatgtcttc acctgccatg acatcccctt  13140

ctcctgtttc ctccacatca ccacagagca tcccctcctc tcctcttcct gtgactgcac  13200

ttcctacttc tgttctggtg acaaccacag atgtgttggg cacaacaagc ccagagtctg  13260

taaccagttc acctccaaat ttgagcagca tcactcatga gagaccggcc acttacaaag  13320

acactgcaca cacagaagcc gccatgcatc attccacaaa caccgcagtg accaatgtag  13380

ggacttccgg gtctggacat aaatcacaat cctctgtcct agctgactca gagacatcga  13440

aagccacacc tctgatgagt accacctcca ccctggggga cacaagtgtt tccacatcaa  13500

ctcctaatat ctctcagact aaccaaattc aaacagagcc aacagcatcc ctgagcccta  13560

gactgaggga gagcagcacg tctgagaaga ccagctcaac aacagagaca aatactgcct  13620

tttcttatgt gcccacaggt gctattactc aggcctccag aacagaaatc tcctctagca  13680

gaacatccat ctcagacctt gatcggccca caatagcacc cgacatctcc acaggaatga  13740

tcaccaggct cttcacctcc cccatcatga caaaatctgc agaaatgacc gtcaccactc  13800

aaacaactac tcctggggct acatcacagg gtatccttcc ctgggacaca tcaaccacac  13860

ttttccaggg agggactcat tcaaccgtgt ctcagggatt cccacactca gagataacca  13920

ctcttcggag cagaacccct ggagatgtgt catggatgac aactccccct gtggaagaaa  13980

ccagctctgg gttttccctg atgtcacctt ccatgacatc cccttctcct gtttcctcca  14040

catcaccaga gagcatcccc tcctctcctc tccctgtgac tgcacttctt acttctgttc  14100

tggtgacaac cacaaatgta ttgggcacaa caagcccaga gcccgtaacg agttcacctc  14160

caaatttaag cagccccaca caggagagac tgaccactta caaagacact gcgcacacag  14220

aagccatgca tgcttccatg catacaaaca ctgcagtggc caacgtgggg acctccattt  14280

ctggacatga atcacaatct tctgtcccag ctgattcaca cacatccaaa gccacatctc  14340

caatgggtat caccttcgcc atgggggata caagtgtttc tacatcaact cctgccttct  14400

ttgagactag aattcagact gaatcaacat cctctttgat tcctggatta agggacacca  14460

ggacgtctga ggagatcaac actgtgacag agaccagcac tgtcctttca gaagtgccca  14520

ctactactac tactgaggtc tccaggacag aagttatcac ttccagcaga acaaccatct  14580

cagggcctga tcattccaaa atgtcaccct acatctccac agaaaccatc accaggctct  14640

ccacttttcc ttttgtaaca ggatccacag aaatggccat caccaaccaa acaggtccta  14700

tagggactat ctcacaggct acccttaccc tggacacatc aagcacagct tcctgggaag  14760

ggactcactc acctgtgact cagagatttc cacactcaga ggagaccact actatgagca  14820

gaagtactaa gggcgtgtca tggcaaagcc ctccctctgt ggaagaaacc agttctcctt  14880

cttccccagt gcctttacct gcaataacct cacattcatc tctttattcc gcagtatcag  14940

gaagtagccc cacttctgct ctccctgtga cttcccttct cacctctggc aggaggaaga  15000

ccatagacat gttggacaca cactcagaac ttgtgaccag ctccttacca agtgcaagta  15060

gcttctcagg tgagatactc acttctgaag cctccacaaa tacagagaca attcactttt  15120

cagagaacac agcagaaacc aatatgggga ccaccaattc tatgcataaa ctacattcct  15180

ctgtctcaat ccactcccag ccatccggac acacacctcc aaaggttact ggatctatga  15240

tggaggacgc tattgtttcc acatcaacac ctggttctcc tgagactaaa aatgttgaca  15300

gagactcaac atcccctctg actcctgaac tgaaagagga cagcaccgcc ctggtgatga  15360

actcaactac agagtcaaac actgttttct ccagtgtgtc cctggatgct gctactgagg  15420

tctccagggc agaagtcacc tactatgatc ctacattcat gccagcttct gctcagtcaa  15480

caaagtcccc agacatttca cctgaagcca gcagcagtca ttctaactct cctcccttga  15540

caatatctac acacaagacc atcgccacac aaacaggtcc ttctggggtg acatctcttg  15600

gccaactgac cctggacaca tcaaccatag ccacctcagc aggaactcca tcagccagaa  15660

ctcaggattt tgtagattca gaaacaacca gtgtcatgaa caatgatctc aatgatgtgt  15720

tgaagacaag ccctttctct gcagaagaag ccaactctct ctcttctcag gcacctctcc  15780

ttgtgacaac ctcaccttct cctgtaactt ccacattgca agagcacagt acctcctctc  15840

ttgtttctgt gacctcagta cccaccccta cactggcgaa gatcacagac atggacacaa  15900

acttagaacc tgtgactcgt tcacctcaaa atttaaggaa caccttggcc acttcagaag  15960

ccaccacaga tacacacaca atgcatcctt ctataaacac agcagtggcc aatgtgggga  16020

ccaccagttc accaaatgaa ttctatttta ctgtctcacc tgactcagac ccatataaag  16080

ccacatccgc agtagttatc acttccacct cgggggactc aatagtttcc acatcaatgc  16140

ctagatcctc tgcgatgaaa aagattgagt ctgagacaac tttctccctg atatttagac  16200

tgagggagac tagcacctcc cagaaaattg gctcatcctc agacacaagc acggtctttg  16260

acaaagcatt cactgctgct actactgagg tctccagaac agaactcacc tcctctagca  16320

gaacatccat ccaaggcact gaaaagccca caatgtcacc ggacacctcc acaagatctg  16380

tcaccatgct ttctactttt gctggcctga caaaatccga agaaaggacc attgccaccc  16440

aaacaggtcc tcatagggcg acatcacagg gtacccttac ctgggacaca tcaatcacaa  16500

cctcacaggc agggacccac tcagctatga ctcatggatt ttcacaatta gatttgtcca  16560

ctcttacgag tagagttcct gagtacatat cagggacaag cccaccctct gtggaaaaaa  16620

ccagctcttc ctcttccctt ctgtctttac cagcaataac ctcaccgtcc cctgtaccta  16680

ctacattacc agaaagtagg ccgtcttctc ctgttcatct gacttcactc cccacctctg  16740

gcctagtgaa gaccacagat atgctggcat ctgtggccag tttacctcca aacttgggca  16800

gcacctcaca taagataccg actacttcag aagacattaa agatacagag aaaatgtatc  16860

cttccacaaa catagcagta accaatgtgg ggaccaccac ttctgaaaag gaatcttatt  16920

cgtctgtccc agcctactca gaaccaccca aagtcacctc tccaatggtt acctctttca  16980

acataaggga caccattgtt tccacatcca tgcctggctc ctctgagatt acaaggattg  17040

agatggagtc aacattctcc ctggctcatg ggctgaaggg aaccagcacc tcccaggacc  17100

ccatcgtatc cacagagaaa agtgctgtcc ttcacaagtt gaccactggt gctactgaga  17160

cctctaggac agaagttgcc tcttctagaa gaacatccat tccaggccct gatcattcca  17220

cagagtcacc agacatctcc actgaagtga tccccagcct gcctatctcc cttggcatta  17280

cagaatcttc aaatatgacc atcatcactc gaacaggtcc tcctcttggc tctacatcac  17340

agggcacatt taccttggac acaccaacta catcctccag ggcaggaaca cactcgatgg  17400

cgactcagga atttccacac tcagaaatga ccactgtcat gaacaaggac cctgagattc  17460

tatcatggac aatccctcct tctatagaga aaaccagctt ctcctcttcc ctgatgcctt  17520

caccagccat gacttcacct cctgtttcct caacattacc aaagaccatt cacaccactc  17580

cttctcctat gacctcactg ctcaccccta gcctagtgat gaccacagac acattgggca  17640

caagcccaga acctacaacc agttcacctc caaatttgag cagtacctca catgagatac  17700

tgacaacaga tgaagacacc acagctatag aagccatgca tccttccaca agcacagcag  17760

cgactaatgt ggaaaccacc agttctggac atgggtcaca atcctctgtc ctagctgact  17820

cagaaaaaac caaggccaca gctccaatgg ataccacctc caccatgggg catacaactg  17880

tttccacatc aatgtctgtt tcctctgaga ctacaaaaat taagagagag tcaacatatt  17940

ccttgactcc tggactgaga gagaccagca tttcccaaaa tgccagcttt tccactgaca  18000

caagtattgt tctttcagaa gtccccactg gtactactgc tgaggtctcc aggacagaag  18060

tcacctcctc tggtagaaca tccatccctg gcccttctca gtccacagtt ttgccagaaa  18120

tatccacaag aacaatgaca aggctctttg cctcgcccac catgacagaa tcagcagaaa  18180

tgaccatccc cactcaaaca ggtccttctg ggtctacctc acaggatacc cttaccttgg  18240

acacatccac cacaaagtcc caggcaaaga ctcattcaac tttgactcag agatttccac  18300

actcagagat gaccactctc atgagcagag gtcctggaga tatgtcatgg caaagctctc  18360

cctctctgga aaatcccagc tctctccctt ccctgctgtc tttacctgcc acaacctcac  18420

ctcctcccat ttcctccaca ttaccagtga ctatctcctc ctctcctctt cctgtgactt  18480

cacttctcac ctctagcccg gtaacgacca cagacatgtt acacacaagc ccagaacttg  18540

taaccagttc acctccaaag ctgagccaca cttcagatga gagactgacc actggcaagg  18600

acaccacaaa tacagaagct gtgcatcctt ccacaaacac agcagcgtcc aatgtggaga  18660

ttcccagctc tggacatgaa tccccttcct ctgccttagc tgactcagag acatccaaag  18720

ccacatcacc aatgtttatt acctccaccc aggaggatac aactgttgcc atatcaaccc  18780

ctcacttctt ggagactagc agaattcaga aagagtcaat ttcctccctg agccctaaat  18840

tgagggagac aggcagttct gtggagacaa gctcagccat agagacaagt gctgtccttt  18900

ctgaagtgtc cattggtgct actactgaga tctccaggac agaagtcacc tcctctagca  18960

gaacatccat ctctggttct gctgagtcca caatgttgcc agaaatatcc accacaagaa  19020

aaatcattaa gttccctact tcccccatcc tggcagaatc atcagaaatg accatcaaga  19080

cccaaacaag tcctcctggg tctacatcag agagtacctt tacattagac acatcaacca  19140

ctccctcctt ggtaataacc cattcgacta tgactcagag attgccacac tcagagataa  19200

ccactcttgt gagtagaggt gctggggatg tgccacggcc cagctctctc cctgtggaag  19260

aaacaagccc tccatcttcc cagctgtctt tatctgccat gatctcacct tctcctgttt  19320

cttccacatt accagcaagt agccactcct cttctgcttc tgtgacttca cttctcacac  19380

caggccaagt gaagactact gaggtgttgg acgcaagtgc agaacctgaa accagttcac  19440

ctccaagttt gagcagcacc tcagttgaaa tactggccac ctctgaagtc accacagata  19500

cggagaaaat tcatcctttc tcaaacacgg cagtaaccaa agttggaact tccagttctg  19560

gacatgaatc cccttcctct gtcctacctg actcagagac aaccaaagcc acatcggcaa  19620

tgggtaccat ctccattatg ggggatacaa gtgtttctac attaactcct gccttatcta  19680

acactaggaa aattcagtca gagccagctt cctcactgac caccagattg agggagacca  19740

gcacctctga agagaccagc ttagccacag aagcaaacac tgttctttct aaagtgtcca  19800

ctggtgctac tactgaggtc tccaggacag aagccatctc ctttagcaga acatccatgt  19860

caggccctga gcagtccaca atgtcacaag acatctccat aggaaccatc cccaggattt  19920

ctgcctcctc tgtcctgaca gaatctgcaa aaatgaccat cacaacccaa acaggtcctt  19980

cggagtctac actagaaagt acccttaatt tgaacacagc aaccacaccc tcttgggtgg  20040

aaacccactc tatagtaatt cagggatttc cacacccaga gatgaccact tccatgggca  20100

gaggtcctgg aggtgtgtca tggcctagcc ctccctttgt gaaagaaacc agccctccat  20160

cctccccgct gtctttacct gccgtgacct cacctcatcc tgtttccacc acattcctag  20220

cacatatccc cccctctccc cttcctgtga cttcacttct cacctctggc ccggcgacaa  20280

ccacagatat cttgggtaca agcacagaac ctggaaccag ttcatcttca agtttgagca  20340

ccacctccca tgagagactg accacttaca aagacactgc acatacagaa gccgtgcatc  20400

cttccacaaa cacaggaggg accaatgtgg caaccaccag ctctggatat aaatcacagt  20460

cctctgtcct agctgactca tctccaatgt gtaccacctc caccatgggg gatacaagtg  20520

ttctcacatc aactcctgcc ttccttgaga ctaggaggat tcagacagag ctagcttcct  20580

ccctgacccc tggattgagg gagtccagcg gctctgaagg gaccagctca ggcaccaaga  20640

tgagcactgt cctctctaaa gtgcccactg gtgctactac tgagatctcc aaggaagacg  20700

tcacctccat cccaggtccc gctcaatcca caatatcacc agacatctcc acaagaaccg  20760

tcagctggtt ctctacatcc cctgtcatga cagaatcagc agaaataacc atgaacaccc  20820

atacaagtcc tttaggggcc acaacacaag gcaccagtac tttggacacg tcaagcacaa  20880

cctctttgac aatgacacac tcaactatat ctcaaggatt ttcacactca cagatgagca  20940

ctcttatgag gaggggtcct gaggatgtat catggatgag ccctcccctt ctggaaaaaa  21000

ctagaccttc cttttctctg atgtcttcac cagccacaac ttcaccttct cctgtttcct  21060

ccacattacc agagagcatc tcttcctctc ctcttcctgt gacttcactc ctcacgtctg  21120

gcttggcaaa aactacagat atgttgcaca aaagctcaga acctgtaacc aactcacctg  21180

caaatttgag cagcacctca gttgaaatac tggccacctc tgaagtcacc acagatacag  21240

agaaaactca tccttcttca aacagaacag tgaccgatgt ggggacctcc agttctggac  21300

atgaatccac ttcctttgtc ctagctgact cacagacatc caaagtcaca tctccaatgg  21360

ttattacctc caccatggag gatacgagtg tctccacatc aactcctggc ttttttgaga  21420

ctagcagaat tcagacagaa ccaacatcct ccctgaccct tggactgaga aagaccagca  21480

gctctgaggg gaccagctta gccacagaga tgagcactgt cctttctgga gtgcccactg  21540

gtgccactgc tgaagtctcc aggacagaag tcacctcctc tagcagaaca tccatctcag  21600

gctttgctca gctcacagtg tcaccagaga cttccacaga aaccatcacc agactcccta  21660

cctccagcat aatgacagaa tcagcagaaa tgatgatcaa gacacaaaca gatcctcctg  21720

ggtctacacc agagagtact catactgtgg acatatcaac aacacccaac tgggtagaaa  21780

cccactcgac tgtgactcag agattttcac actcagagat gaccactctt gtgagcagaa  21840

gccctggtga tatgttatgg cctagtcaat cctctgtgga agaaaccagc tctgcctctt  21900

ccctgctgtc tctgcctgcc acgacctcac cttctcctgt ttcctctaca ttagtagagg  21960

atttcccttc cgcttctctt cctgtgactt ctcttctcaa ccctggcctg gtgataacca  22020

cagacaggat gggcataagc agagaacctg gaaccagttc cacttcaaat ttgagcagca  22080

cctcccatga gagactgacc actttggaag acactgtaga tacagaagac atgcagcctt  22140

ccacacacac agcagtgacc aacgtgagga cctccatttc tggacatgaa tcacaatctt  22200

ctgtcctatc tgactcagag acacccaaag ccacatctcc aatgggtacc acctacacca  22260

tgggggaaac gagtgtttcc atatccactt ctgacttctt tgagaccagc agaattcaga  22320

tagaaccaac atcctccctg acttctggat tgagggagac cagcagctct gagaggatca  22380

gctcagccac agagggaagc actgtccttt ctgaagtgcc cagtggtgct accactgagg  22440

tctccaggac agaagtgata tcctctaggg gaacatccat gtcagggcct gatcagttca  22500

ccatatcacc agacatctct actgaagcga tcaccaggct ttctacttcc cccattatga  22560

cagaatcagc agaaagtgcc atcactattg agacaggttc tcctggggct acatcagagg  22620

gtaccctcac cttggacacc tcaacaacaa ccttttggtc agggacccac tcaactgcat  22680

ctccaggatt ttcacactca gagatgacca ctcttatgag tagaactcct ggagatgtgc  22740

catggccgag ccttccctct gtggaagaag ccagctctgt ctcttcctca ctgtcttcac  22800

ctgccatgac ctcaacttct tttttctcca cattaccaga gagcatctcc tcctctcctc  22860

atcctgtgac tgcacttctc acccttggcc cagtgaagac cacagacatg ttgcgcacaa  22920

gctcagaacc tgaaaccagt tcacctccaa atttgagcag cacctcagct gaaatattag  22980

ccacgtctga agtcaccaaa gatagagaga aaattcatcc ctcctcaaac acacctgtag  23040

tcaatgtagg gactgtgatt tataaacatc tatccccttc ctctgttttg gctgacttag  23100

tgacaacaaa acccacatct ccaatggcta ccacctccac tctggggaat acaagtgttt  23160

ccacatcaac tcctgccttc ccagaaacta tgatgacaca gccaacttcc tccctgactt  23220

ctggattaag ggagatcagt acctctcaag agaccagctc agcaacagag agaagtgctt  23280

ctctttctgg aatgcccact ggtgctacta ctaaggtctc cagaacagaa gccctctcct  23340

taggcagaac atccacccca ggtcctgctc aatccacaat atcaccagaa atctccacgg  23400

aaaccatcac tagaatttct actcccctca ccacgacagg atcagcagaa atgaccatca  23460

cccccaaaac aggtcattct ggggcatcct cacaaggtac ctttaccttg gacacatcaa  23520

gcagagcctc ctggccagga actcactcag ctgcaactca cagatctcca cactcaggga  23580

tgaccactcc tatgagcaga ggtcctgagg atgtgtcatg gccaagccgc ccatcagtgg  23640

aaaaaactag ccctccatct tccctggtgt ctttatctgc agtaacctca ccttcgccac  23700

tttattccac accatctgag agtagccact catctcctct ccgggtgact tctcttttca  23760

cccctgtcat gatgaagacc acagacatgt tggacacaag cttggaacct gtgaccactt  23820

cacctcccag tatgaatatc acctcagatg agagtctggc cacttctaaa gccaccatgg  23880

agacagaggc aattcagctt tcagaaaaca cagctgtgac tcagatgggc accatcagcg  23940

ctagacaaga attctattcc tcttatccag gcctcccaga gccatccaaa gtgacatctc  24000

cagtggtcac ctcttccacc ataaaagaca ttgtttctac aaccatacct gcttcctctg  24060

agataacaag aattgagatg gagtcaacat ccaccctgac ccccacacca agggagacca  24120

gcacctccca ggagatccac tcagccacaa agccaagcac tgttccttac aaggcactca  24180

ctagtgccac gattgaggac tccatgacac aagtcatgtc ctctagcaga ggacctagcc  24240

ctgatcagtc cacaatgtca caagacatat ccactgaagt gatcaccagg ctctctacct  24300

cccccatcaa gacagaatct acagaaatga ccattaccac ccaaacaggt tctcctgggg  24360

ctacatcaag gggtaccctt accttggaca cttcaacaac ttttatgtca gggacccact  24420

caactgcatc tcaaggattt tcacactcac agatgaccgc tcttatgagt agaactcctg  24480

gagatgtgcc atggctaagc catccctctg tggaagaagc cagctctgcc tctttctcac  24540

tgtcttcacc tgtcatgacc tcatcttctc ccgtttcttc cacattacca gacagcatcc  24600

actcttcttc gcttcctgtg acatcacttc tcacctcagg gctggtgaag accacagagc  24660

tgttgggcac aagctcagaa cctgaaacca gttcaccccc aaatttgagc agcacctcag  24720

ctgaaatact ggccatcact gaagtcacta cagatacaga gaaactggag atgaccaatg  24780

tggtaacctc aggttataca catgaatctc cttcctctgt cctagctgac tcagtgacaa  24840

caaaggccac atcttcaatg ggtatcacct accccacagg agatacaaat gttctcacat  24900

caacccctgc cttctctgac accagtagga ttcaaacaaa gtcaaagctc tcactgactc  24960

ctgggttgat ggagaccagc atctctgaag agaccagctc tgccacagaa aaaagcactg  25020

tcctttctag tgtgcccact ggtgctacta ctgaggtctc caggacagaa gccatctctt  25080

ctagcagaac atccatccca ggccctgctc aatccacaat gtcatcagac acctccatgg  25140

aaaccatcac tagaatttct acccccctca caaggaaaga atcaacagac atggccatca  25200

cccccaaaac aggtccttct ggggctacct cgcagggtac ctttaccttg gactcatcaa  25260

gcacagcctc ctggccagga actcactcag ctacaactca gagatttcca cagtcagtgg  25320

tgacaactcc tatgagcaga ggtcctgagg atgtgtcatg gccaagcccg ctgtctgtgg  25380

aaaaaaacag ccctccatct tccctggtat cttcatcttc agtaacctca ccttcgccac  25440

tttattccac accatctggg agtagccact cctctcctgt ccctgtcact tctcttttca  25500

cctctatcat gatgaaggcc acagacatgt tggatgcaag tttggaacct gagaccactt  25560

cagctcccaa tatgaatatc acctcagatg agagtctggc cgcttctaaa gccaccacgg  25620

agacagaggc aattcacgtt tttgaaaata cagcagcgtc ccatgtggaa accaccagtg  25680

ctacagagga actctattcc tcttccccag gcttctcaga gccaacaaaa gtgatatctc  25740

cagtggtcac ctcttcctct ataagagaca acatggtttc cacaacaatg cctggctcct  25800

ctggcattac aaggattgag atagagtcaa tgtcatctct gacccctgga ctgagggaga  25860

ccagaacctc ccaggacatc acctcatcca cagagacaag cactgtcctt tacaagatgc  25920

cctctggtgc cactcctgag gtctccagga cagaagttat gccctctagc agaacatcca  25980

ttcctggccc tgctcagtcc acaatgtcac tagacatctc cgatgaagtt gtcaccaggc  26040

tgtctacctc tcccatcatg acagaatctg cagaaataac catcaccacc caaacaggtt  26100

attctctggc tacatcccag gttacccttc ccttgggcac ctcaatgacc tttttgtcag  26160

ggacccactc aactatgtct caaggacttt cacactcaga gatgaccaat cttatgagca  26220

ggggtcctga aagtctgtca tggacgagcc ctcgctttgt ggaaacaact agatcttcct  26280

cttctctgac atcattacct ctcacgacct cactttctcc tgtgtcctcc acattactag  26340

acagtagccc ctcctctcct cttcctgtga cttcacttat cctcccaggc ctggtgaaga  26400

ctacagaagt gttggataca agctcagagc ctaaaaccag ttcatctcca aatttgagca  26460

gcacctcagt tgaaataccg gccacctctg aaatcatgac agatacagag aaaattcatc  26520

cttcctcaaa cacagcggtg gccaaagtga ggacctccag ttctgttcat gaatctcatt  26580

cctctgtcct agctgactca gaaacaacca taaccatacc ttcaatgggt atcacctccg  26640

ctgtggacga taccactgtt ttcacatcaa atcctgcctt ctctgagact aggaggattc  26700

cgacagagcc aacattctca ttgactcctg gattcaggga gactagcacc tctgaagaga  26760

ccacctcaat cacagaaaca agtgcagtcc tttatggagt gcccactagt gctactactg  26820

aagtctccat gacagaaatc atgtcctcta atagaataca catccctgac tctgatcagt  26880

ccacgatgtc tccagacatc atcactgaag tgatcaccag gctctcttcc tcatccatga  26940

tgtcagaatc aacacaaatg accatcacca cccaaaaaag ttctcctggg gctacagcac  27000

agagtactct taccttggcc acaacaacag cccccttggc aaggacccac tcaactgttc  27060

ctcctagatt tttacactca gagatgacaa ctcttatgag taggagtcct gaaaatccat  27120

catggaagag ctctctcttt gtggaaaaaa ctagctcttc atcttctctg ttgtccttac  27180

ctgtcacgac ctcaccttct gtttcttcca cattaccgca gagtatccct tcctcctctt  27240

tttctgtgac ttcactcctc accccaggca tggtgaagac tacagacaca agcacagaac  27300

ctggaaccag tttatctcca aatctgagtg gcacctcagt tgaaatactg gctgcctctg  27360

aagtcaccac agatacagag aaaattcatc cttcttcaag catggcagtg accaatgtgg  27420

gaaccaccag ttctggacat gaactatatt cctctgtttc aatccactcg gagccatcca  27480

aggctacata cccagtgggt actccctctt ccatggctga aacctctatt tccacatcaa  27540

tgcctgctaa ttttgagacc acaggatttg aggctgagcc attttctcat ttgacttctg  27600

gatttaggaa gacaaacatg tccctggaca ccagctcagt cacaccaaca aatacacctt  27660

cttctcctgg gtccactcac cttttacaga gttccaagac tgatttcacc tcttctgcaa  27720

aaacatcatc cccagactgg cctccagcct cacagtatac tgaaattcca gtggacataa  27780

tcaccccctt taatgcttct ccatctatta cggagtccac tgggataacc tccttcccag  27840

aatccaggtt tactatgtct gtaacagaaa gtactcatca tctgagtaca gatttgctgc  27900

cttcagctga gactatttcc actggcacag tgatgccttc tctatcagag gccatgactt  27960

catttgccac cactggagtt ccacgagcca tctcaggttc aggtagtcca ttctctagga  28020

cagagtcagg ccctggggat gctactctgt ccaccattgc agagagcctg ccttcatcca  28080

ctcctgtgcc attctcctct tcaaccttca ctaccactga ttcttcaacc atcccagccc  28140

tccatgagat aacttcctct tcagctaccc catatagagt ggacaccagt cttgggacag  28200

agagcagcac tactgaagga cgcttggtta tggtcagtac tttggacact tcaagccaac  28260

caggcaggac atcttcatca cccattttgg ataccagaat gacagagagc gttgagctgg  28320

gaacagtgac aagtgcttat caagttcctt cactctcaac acggttgaca agaactgatg  28380

gcattatgga acacatcaca aaaataccca atgaagcagc acacagaggt accataagac  28440

cagtcaaagg ccctcagaca tccacttcgc ctgccagtcc taaaggacta cacacaggag  28500

ggacaaaaag aatggagacc accaccacag ctctgaagac caccaccaca gctctgaaga  28560

ccacttccag agccaccttg accaccagtg tctatactcc cactttggga acactgactc  28620

ccctcaatgc atcaatgcaa atggccagca caatccccac agaaatgatg atcacaaccc  28680

catatgtttt ccctgatgtt ccagaaacga catcctcatt ggctaccagc ctgggagcag  28740

aaaccagcac agctcttccc aggacaaccc catctgtttt caatagagaa tcagagacca  28800

cagcctcact ggtctctcgt tctggggcag agagaagtcc ggttattcaa actctagatg  28860

tttcttctag tgagccagat acaacagctt catgggttat ccatcctgca gagaccatcc  28920

caactgtttc caagacaacc cccaattttt tccacagtga attagacact gtatcttcca  28980

cagccaccag tcatggggca gacgtcagct cagccattcc aacaaatatc tcacctagtg  29040

aactagatgc actgacccca ctggtcacta tttcggggac agatactagt acaacattcc  29100

caacactgac taagtcccca catgaaacag agacaagaac cacatggctc actcatcctg  29160

cagagaccag ctcaactatt cccagaacaa tccccaattt ttctcatcat gaatcagatg  29220

ccacaccttc aatagccacc agtcctgggg cagaaaccag ttcagctatt ccaattatga  29280

ctgtctcacc tggtgcagaa gatctggtga cctcacaggt cactagttct gggacagaca  29340

gaaatatgac tattccaact ttgactcttt ctcctggtga accaaagacg atagcctcat  29400

tagtcaccca tcctgaagca cagacaagtt cggccattcc aacttcaact atctcgcctg  29460

ctgtatcacg gttggtgacc tcaatggtca ccagtttggc ggcaaagaca agtacaacta  29520

atcgagctct gacaaactcc cctggtgaac cagctacaac agtttcattg gtcacgcatc  29580

ctgcacagac cagcccaaca gttccctgga caacttccat ttttttccat agtaaatcag  29640

acaccacacc ttcaatgacc accagtcatg gggcagaatc cagttcagct gttccaactc  29700

caactgtttc aactgaggta ccaggagtag tgaccccttt ggtcaccagt tctagggcag  29760

tgatcagtac aactattcca attctgactc tttctcctgg tgaaccagag accacacctt  29820

caatggccac cagtcatggg gaagaagcca gttctgctat tccaactcca actgtttcac  29880

ctggggtacc aggagtggtg acctctctgg tcactagttc tagggcagtg actagtacaa  29940

ctattccaat tctgactttt tctcttggtg aaccagagac cacaccttca atggccacca  30000

gtcatgggac agaagctggc tcagctgttc caactgtttt acctgaggta ccaggaatgg  30060

tgacctctct ggttgctagt tctagggcag taaccagtac aactcttcca actctgactc  30120

tttctcctgg tgaaccagag accacacctt caatggccac cagtcatggg gcagaagcca  30180

gctcaactgt tccaactgtt tcacctgagg taccaggagt ggtgacctct ctggtcacta  30240

gttctagtgg agtaaacagt acaagtattc caactctgat tctttctcct ggtgaactag  30300

aaaccacacc ttcaatggcc accagtcatg gggcagaagc cagctcagct gttccaactc  30360

caactgtttc acctggggta tcaggagtgg tgacccctct ggtcactagt tccagggcag  30420

tgaccagtac aactattcca attctaactc tttcttctag tgagccagag accacacctt  30480

caatggccac cagtcatggg gtagaagcca gctcagctgt tctaactgtt tcacctgagg  30540

taccaggaat ggtgacctct ctggtcacta gttctagagc agtaaccagt acaactattc  30600

caactctgac tatttcttct gatgaaccag agaccacaac ttcattggtc acccattctg  30660

aggcaaagat gatttcagcc attccaactt tagctgtctc ccctactgta caagggctgg  30720

tgacttcact ggtcactagt tctgggtcag agaccagtgc gttttcaaat ctaactgttg  30780

cctcaagtca accagagacc atagactcat gggtcgctca tcctgggaca gaagcaagtt  30840

ctgttgttcc aactttgact gtctccactg gtgagccgtt tacaaatatc tcattggtca  30900

cccatcctgc agagagtagc tcaactcttc ccaggacaac ctcaaggttt tcccacagtg  30960

aattagacac tatgccttct acagtcacca gtcctgaggc agaatccagc tcagccattt  31020

caacaactat ttcacctggt ataccaggtg tgctgacatc actggtcact agctctggga  31080

gagacatcag tgcaactttt ccaacagtgc ctgagtcccc acatgaatca gaggcaacag  31140

cctcatgggt tactcatcct gcagtcacca gcacaacagt tcccaggaca acccctaatt  31200

attctcatag tgaaccagac accacaccat caatagccac cagtcctggg gcagaagcca  31260

cttcagattt tccaacaata actgtctcac ctgatgtacc agatatggta acctcacagg  31320

tcactagttc tgggacagac accagtataa ctattccaac tctgactctt tcttctggtg  31380

agccagagac cacaacctca tttatcacct attctgagac acacacaagt tcagccattc  31440

caactctccc tgtctcccct ggtgcatcaa agatgctgac ctcactggtc atcagttctg  31500

ggacagacag cactacaact ttcccaacac tgacggagac cccatatgaa ccagagacaa  31560

cagccataca gctcattcat cctgcagaga ccaacacaat ggttcccagg acaactccca  31620

agttttccca tagtaagtca gacaccacac tcccagtagc catcaccagt cctgggccag  31680

aagccagttc agctgtttca acgacaacta tctcacctga tatgtcagat ctggtgacct  31740

cactggtccc tagttctggg acagacacca gtacaacctt cccaacattg agtgagaccc  31800

catatgaacc agagactaca gccacgtggc tcactcatcc tgcagaaacc agcacaacgg  31860

tttctgggac aattcccaac ttttcccata ggggatcaga cactgcaccc tcaatggtca  31920

ccagtcctgg agtagacacg aggtcaggtg ttccaactac aaccatccca cccagtatac  31980

caggggtagt gacctcacag gtcactagtt ctgcaacaga cactagtaca gctattccaa  32040

ctttgactcc ttctcctggt gaaccagaga ccacagcctc atcagctacc catcctggga  32100

cacagactgg cttcactgtt ccaattcgga ctgttccctc tagtgagcca gatacaatgg  32160

cttcctgggt cactcatcct ccacagacca gcacacctgt ttccagaaca acctccagtt  32220

tttcccatag tagtccagat gccacacctg taatggccac cagtcctagg acagaagcca  32280

gttcagctgt actgacaaca atctcacctg gtgcaccaga gatggtgact tcacagatca  32340

ctagttctgg ggcagcaacc agtacaactg ttccaacttt gactcattct cctggtatgc  32400

cagagaccac agccttattg agcacccatc ccagaacaga gacaagtaaa acatttcctg  32460

cttcaactgt gtttcctcaa gtatcagaga ccacagcctc actcaccatt agacctggtg  32520

cagagactag cacagctctc ccaactcaga caacatcctc tctcttcacc ctacttgtaa  32580

ctggaaccag cagagttgat ctaagtccaa ctgcttcacc tggtgtttct gcaaaaacag  32640

ccccactttc cacccatcca gggacagaaa ccagcacaat gattccaact tcaactcttt  32700

cccttggttt actagagact acaggcttac tggccaccag ctcttcagca gagaccagca  32760

cgagtactct aactctgact gtttcccctg ctgtctctgg gctttccagt gcctctataa  32820

caactgataa gccccaaact gtgacctcct ggaacacaga aacctcacca tctgtaactt  32880

cagttggacc cccagaattt tccaggactg tcacaggcac cactatgacc ttgataccat  32940

cagagatgcc aacaccacct aaaaccagtc atggagaagg agtgagtcca accactatct  33000

tgagaactac aatggttgaa gccactaatt tagctaccac aggttccagt cccactgtgg  33060

ccaagacaac aaccaccttc aatacactgg ctggaagcct ctttactcct ctgaccacac  33120

ctgggatgtc caccttggcc tctgagagtg tgacctcaag aacaagttat aaccatcggt  33180

cctggatctc caccaccagc agttataacc gtcggtactg gacccctgcc accagcactc  33240

cagtgacttc tacattctcc ccagggattt ccacatcctc catccccagc tccacagcag  33300

ccacagtccc attcatggtg ccattcaccc tcaacttcac catcaccaac ctgcagtacg  33360

aggaggacat gcggcaccct ggttccagga agttcaacgc cacagagaga gaactgcagg  33420

gtctgctcaa acccttgttc aggaatagca gtctggaata cctctattca ggctgcagac  33480

tagcctcact caggccagag aaggatagct cagccacggc agtggatgcc atctgcacac  33540

atcgccctga ccctgaagac ctcggactgg acagagagcg actgtactgg gagctgagca  33600

atctgacaaa tggcatccag gagctgggcc cctacaccct ggaccggaac agtctctatg  33660

tcaatggttt cacccatcga agctctatgc ccaccaccag cactcctggg acctccacag  33720

tggatgtggg aacctcaggg actccatcct ccagccccag ccccacgact gctggccctc  33780

tcctgatgcc gttcaccctc aacttcacca tcaccaacct gcagtacgag gaggacatgc  33840

gtcgcactgg ctccaggaag ttcaacacca tggagagtgt cctgcagggt ctgctcaagc  33900

ccttgttcaa gaacaccagt gttggccctc tgtactctgg ctgcagattg accttgctca  33960

ggcccgagaa agatggggca gccactggag tggatgccat ctgcacccac cgccttgacc  34020

ccaaaagccc tggactcaac agggagcagc tgtactggga gctaagcaaa ctgaccaatg  34080

acattgaaga gctgggcccc tacaccctgg acaggaacag tctctatgtc aatggtttca  34140

cccatcagag ctctgtgtcc accaccagca ctcctgggac ctccacagtg gatctcagaa  34200

cctcagggac tccatcctcc ctctccagcc ccacaattat ggctgctggc cctctcctgg  34260

taccattcac cctcaacttc accatcacca acctgcagta tggggaggac atgggtcacc  34320

ctggctccag gaagttcaac accacagaga gggtcctgca gggtctgctt ggtcccatat  34380

tcaagaacac cagtgttggc cctctgtact ctggctgcag actgacctct ctcaggtctg  34440

agaaggatgg agcagccact ggagtggatg ccatctgcat ccatcatctt gaccccaaaa  34500

gccctggact caacagagag cggctgtact gggagctgag ccaactgacc aatggcatca  34560

aagagctggg cccctacacc ctggacagga acagtctcta tgtcaatggt ttcacccatc  34620

ggacctctgt gcccaccagc agcactcctg ggacctccac agtggacctt ggaacctcag  34680

ggactccatt ctccctccca agccccgcaa ctgctggccc tctcctggtg ctgttcaccc  34740

tcaacttcac catcaccaac ctgaagtatg aggaggacat gcatcgccct ggctccagga  34800

agttcaacac cactgagagg gtcctgcaga ctctgcttgg tcctatgttc aagaacacca  34860

gtgttggcct tctgtactct ggctgcagac tgaccttgct caggtccgag aaggatggag  34920

cagccactgg agtggatgcc atctgcaccc accgtcttga ccccaaaagc cctggagtgg  34980

acagggagca gctatactgg gagctgagcc agctgaccaa tggcatcaaa gagctgggcc  35040

cctacaccct ggacaggaac agtctctatg tcaatggttt cacccattgg atccctgtgc  35100

ccaccagcag cactcctggg acctccacag tggaccttgg gtcagggact ccatcctccc  35160

tccccagccc cacaactgct ggccctctcc tggtgccgtt caccctcaac ttcaccatca  35220

ccaacctgaa gtacgaggag gacatgcatt gccctggctc caggaagttc aacaccacag  35280

agagagtcct gcagagtctg cttggtccca tgttcaagaa caccagtgtt ggccctctgt  35340

actctggctg cagactgacc ttgctcaggt ccgagaagga tggagcagcc actggagtgg  35400

atgccatctg cacccaccgt cttgacccca aaagccctgg agtggacagg gagcagctat  35460

actgggagct gagccagctg accaatggca tcaaagagct gggtccctac accctggaca  35520

gaaacagtct ctatgtcaat ggtttcaccc atcagacctc tgcgcccaac accagcactc  35580

ctgggacctc cacagtggac cttgggacct cagggactcc atcctccctc cccagcccta  35640

catctgctgg ccctctcctg gtgccattca ccctcaactt caccatcacc aacctgcagt  35700

acgaggagga catgcatcac ccaggctcca ggaagttcaa caccacggag cgggtcctgc  35760

agggtctgct tggtcccatg ttcaagaaca ccagtgtcgg ccttctgtac tctggctgca  35820

gactgacctt gctcaggcct gagaagaatg gggcagccac tggaatggat gccatctgca  35880

gccaccgtct tgaccccaaa agccctggac tcaacagaga gcagctgtac tgggagctga  35940

gccagctgac ccatggcatc aaagagctgg gcccctacac cctggacagg aacagtctct  36000

atgtcaatgg tttcacccat cggagctctg tggcccccac cagcactcct gggacctcca  36060

cagtggacct tgggacctca gggactccat cctccctccc cagccccaca acagctgttc  36120

ctctcctggt gccgttcacc ctcaacttta ccatcaccaa tctgcagtat ggggaggaca  36180

tgcgtcaccc tggctccagg aagttcaaca ccacagagag ggtcctgcag ggtctgcttg  36240

gtcccttgtt caagaactcc agtgtcggcc ctctgtactc tggctgcaga ctgatctctc  36300

tcaggtctga gaaggatggg gcagccactg gagtggatgc catctgcacc caccacctta  36360

accctcaaag ccctggactg gacagggagc agctgtactg gcagctgagc cagatgacca  36420

atggcatcaa agagctgggc ccctacaccc tggaccggaa cagtctctac gtcaatggtt  36480

tcacccatcg gagctctggg ctcaccacca gcactccttg gacttccaca gttgaccttg  36540

gaacctcagg gactccatcc cccgtcccca gccccacaac caccggccct ctcctggtgc  36600

cattcacact caacttcacc atcactaacc tacagtatga ggagaacatg ggtcaccctg  36660

gctccaggaa gttcaacatc acggagagtg ttctgcaggg tctgctcaag cccttgttca  36720

agagcaccag tgttggccct ctgtattctg gctgcagact gaccttgctc aggcctgaga  36780

aggatggagt agccaccaga gtggacgcca tctgcaccca ccgccctgac cccaaaatcc  36840

ctgggctaga cagacagcag ctatactggg agctgagcca gctgacccac agcatcactg  36900

agctgggacc ctacaccctg gatagggaca gtctctatgt caatggtttc acccagcgga  36960

gctctgtgcc caccaccagc actcctggga ctttcacagt acagccggaa acctctgaga  37020

ctccatcatc cctccctggc cccacagcca ctggccctgt cctgctgcca ttcaccctca  37080

attttaccat cactaacctg cagtatgagg aggacatgcg tcgccctggc tccaggaagt  37140

tcaacaccac ggagagggtc cttcagggtc tgcttatgcc cttgttcaag aacaccagtg  37200

tcagctctct gtactctggt tgcagactga ccttgctcag gcctgagaag gatggggcag  37260

ccaccagagt ggatgctgtc tgcacccatc gtcctgaccc caaaagccct ggactggaca  37320

gagagcggct gtactggaag ctgagccagc tgacccacgg catcactgag ctgggcccct  37380

acaccctgga caggcacagt ctctatgtca atggtttcac ccatcagagc tctatgacga  37440

ccaccagaac tcctgatacc tccacaatgc acctggcaac ctcgagaact ccagcctccc  37500

tgtctggacc catgaccgcc agccctctcc tggtgctatt cacaattaac ttcaccatca  37560

ctaacctgcg gtatgaggag aacatgcatc accctggctc tagaaagttt aacaccacgg  37620

agagagtcct tcagggtctg ctcaggcctg tgttcaagaa caccagtgtt ggccctctgt  37680

actctggctg cagactgacc ttgctcaggc ccaagaagga tggggcagcc accaaagtgg  37740

atgccatctg cacctaccgc cctgatccca aaagccctgg actggacaga gagcagctat  37800

actgggagct gagccagctg acccacagca tcactgagct gggcccctac accctggaca  37860

gggacagtct ctatgtcaat ggtttcacac agcggagctc tgtgcccacc actagcattc  37920

ctgggacccc cacagtggac ctgggaacat ctgggactcc agtttctaaa cctggtccct  37980

cggctgccag ccctctcctg gtgctattca ctctcaactt caccatcacc aacctgcggt  38040

atgaggagaa catgcagcac cctggctcca ggaagttcaa caccacggag agggtccttc  38100

agggcctgct caggtccctg ttcaagagca ccagtgttgg ccctctgtac tctggctgca  38160

gactgacttt gctcaggcct gaaaaggatg ggacagccac tggagtggat gccatctgca  38220

cccaccaccc tgaccccaaa agccctaggc tggacagaga gcagctgtat tgggagctga  38280

gccagctgac ccacaatatc actgagctgg gcccctatgc cctggacaac gacagcctct  38340

ttgtcaatgg tttcactcat cggagctctg tgtccaccac cagcactcct gggaccccca  38400

cagtgtatct gggagcatct aagactccag cctcgatatt tggcccttca gctgccagcc  38460

atctcctgat actattcacc ctcaacttca ccatcactaa cctgcggtat gaggagaaca  38520

tgtggcctgg ctccaggaag ttcaacacta cagagagggt ccttcagggc ctgctaaggc  38580

ccttgttcaa gaacaccagt gttggccctc tgtactctgg ctgcaggctg accttgctca  38640

ggccagagaa agatggggaa gccaccggag tggatgccat ctgcacccac cgccctgacc  38700

ccacaggccc tgggctggac agagagcagc tgtatttgga gctgagccag ctgacccaca  38760

gcatcactga gctgggcccc tacacactgg acagggacag tctctatgtc aatggtttca  38820

cccatcggag ctctgtaccc accaccagca ccggggtggt cagcgaggag ccattcacac  38880

tgaacttcac catcaacaac ctgcgctaca tggcggacat gggccaaccc ggctccctca  38940

agttcaacat cacagacaac gtcatgcagc acctgctcag tcctttgttc cagaggagca  39000

gcctgggtgc acggtacaca ggctgcaggg tcatcgcact aaggtctgtg aagaacggtg  39060

ctgagacacg ggtggacctc ctctgcacct acctgcagcc cctcagcggc ccaggtctgc  39120

ctatcaagca ggtgttccat gagctgagcc agcagaccca tggcatcacc cggctgggcc  39180

cctactctct ggacaaagac agcctctacc ttaacggtta caatgaacct ggtccagatg  39240

agcctcctac aactcccaag ccagccacca cattcctgcc tcctctgtca gaagccacaa  39300

cagccatggg gtaccacctg aagaccctca cactcaactt caccatctcc aatctccagt  39360

attcaccaga tatgggcaag ggctcagcta cattcaactc caccgagggg gtccttcagc  39420

acctgctcag acccttgttc cagaagagca gcatgggccc cttctacttg ggttgccaac  39480

tgatctccct caggcctgag aaggatgggg cagccactgg tgtggacacc acctgcacct  39540

accaccctga ccctgtgggc cccgggctgg acatacagca gctttactgg gagctgagtc  39600

agctgaccca tggtgtcacc caactgggct tctatgtcct ggacagggat agcctcttca  39660

tcaatggcta tgcaccccag aatttatcaa tccggggcga gtaccagata aatttccaca  39720

ttgtcaactg gaacctcagt aatccagacc ccacatcctc agagtacatc accctgctga  39780

gggacatcca ggacaaggtc accacactct acaaaggcag tcaactacat gacacattcc  39840

gcttctgcct ggtcaccaac ttgacgatgg actccgtgtt ggtcactgtc aaggcattgt  39900

tctcctccaa tttggacccc agcctggtgg agcaagtctt tctagataag accctgaatg  39960

cctcattcca ttggctgggc tccacctacc agttggtgga catccatgtg acagaaatgg  40020

agtcatcagt ttatcaacca acaagcagct ccagcaccca gcacttctac ctgaatttca  40080

ccatcaccaa cctaccatat tcccaggaca aagcccagcc aggcaccacc aattaccaga  40140

ggaacaaaag gaatattgag gatgcgctca accaactctt ccgaaacagc agcatcaaga  40200

gttatttttc tgactgtcaa gtttcaacat tcaggtctgt ccccaacagg caccacaccg  40260

gggtggactc cctgtgtaac ttctcgccac tggctcggag agtagacaga gttgccatct  40320

atgaggaatt tctgcggatg acccggaatg gtacccagct gcagaacttc accctggaca  40380

ggagcagtgt ccttgtggat gggtattctc ccaacagaaa tgagccctta actgggaatt  40440

ctgaccttcc cttctgggct gtcatcctca tcggcttggc aggactcctg ggagtcatca  40500

catgcctgat ctgcggtgtc ctggtgacca cccgccggcg gaagaaggaa ggagaataca  40560

acgtccagca acagtgccca ggctactacc agtcacacct agacctggag gatctgcaat  40620

gactggaact tgccggtgcc tggggtgcct ttcccccagc cagggtccaa agaagcttgg  40680

ctggggcaga aataaaccat attggtcgga cac                               40713


<210>  9099
<211>  13511
<212>  PRT
<213>  Homo sapiens

<400>  9099

Met Val Ser Lys Phe Thr Ser Pro Ala Thr Ser Ser Met Glu Ala Thr 
1               5                   10                  15      


Ser Ile Arg Glu Pro Ser Thr Thr Ile Leu Thr Thr Glu Thr Thr Asn 
            20                  25                  30          


Gly Pro Gly Ser Met Ala Val Ala Ser Thr Asn Ile Pro Ile Gly Lys 
        35                  40                  45              


Gly Tyr Ile Thr Glu Gly Arg Leu Asp Thr Ser His Leu Pro Ile Gly 
    50                  55                  60                  


Thr Thr Ala Ser Ser Glu Thr Ser Met Asp Phe Thr Met Ala Lys Glu 
65                  70                  75                  80  


Ser Val Ser Met Ser Val Ser Pro Ser Gln Ser Met Asp Ala Ala Gly 
                85                  90                  95      


Ser Ser Thr Pro Gly Arg Thr Ser Gln Phe Val Asp Thr Phe Ser Asp 
            100                 105                 110         


Asp Val Tyr His Leu Thr Ser Arg Glu Ile Thr Ile Pro Arg Asp Gly 
        115                 120                 125             


Thr Ser Ser Ala Leu Thr Pro Gln Met Thr Ala Thr His Pro Pro Ser 
    130                 135                 140                 


Pro Asp Pro Gly Ser Ala Arg Ser Thr Trp Leu Gly Ile Leu Ser Ser 
145                 150                 155                 160 


Ser Pro Ser Ser Pro Thr Pro Lys Val Thr Met Ser Ser Thr Phe Ser 
                165                 170                 175     


Thr Gln Arg Val Thr Thr Ser Met Ile Met Asp Thr Val Glu Thr Ser 
            180                 185                 190         


Arg Trp Asn Met Pro Asn Leu Pro Ser Thr Thr Ser Leu Thr Pro Ser 
        195                 200                 205             


Asn Ile Pro Thr Ser Gly Ala Ile Gly Lys Ser Thr Leu Val Pro Leu 
    210                 215                 220                 


Asp Thr Pro Ser Pro Ala Thr Ser Leu Glu Ala Ser Glu Gly Gly Leu 
225                 230                 235                 240 


Pro Thr Leu Ser Thr Tyr Pro Glu Ser Thr Asn Thr Pro Ser Ile His 
                245                 250                 255     


Leu Gly Ala His Ala Ser Ser Glu Ser Pro Ser Thr Ile Lys Leu Thr 
            260                 265                 270         


Met Ala Ser Val Val Lys Pro Gly Ser Tyr Thr Pro Leu Thr Phe Pro 
        275                 280                 285             


Ser Ile Glu Thr His Ile His Val Ser Thr Ala Arg Met Ala Tyr Ser 
    290                 295                 300                 


Ser Gly Ser Ser Pro Glu Met Thr Ala Pro Gly Glu Thr Asn Thr Gly 
305                 310                 315                 320 


Ser Thr Trp Asp Pro Thr Thr Tyr Ile Thr Thr Thr Asp Pro Lys Asp 
                325                 330                 335     


Thr Ser Ser Ala Gln Val Ser Thr Pro His Ser Val Arg Thr Leu Arg 
            340                 345                 350         


Thr Thr Glu Asn His Pro Lys Thr Glu Ser Ala Thr Pro Ala Ala Tyr 
        355                 360                 365             


Ser Gly Ser Pro Lys Ile Ser Ser Ser Pro Asn Leu Thr Ser Pro Ala 
    370                 375                 380                 


Thr Lys Ala Trp Thr Ile Thr Asp Thr Thr Glu His Ser Thr Gln Leu 
385                 390                 395                 400 


His Tyr Thr Lys Leu Ala Glu Lys Ser Ser Gly Phe Glu Thr Gln Ser 
                405                 410                 415     


Ala Pro Gly Pro Val Ser Val Val Ile Pro Thr Ser Pro Thr Ile Gly 
            420                 425                 430         


Ser Ser Thr Leu Glu Leu Thr Ser Asp Val Pro Gly Glu Pro Leu Val 
        435                 440                 445             


Leu Ala Pro Ser Glu Gln Thr Thr Ile Thr Leu Pro Met Ala Thr Trp 
    450                 455                 460                 


Leu Ser Thr Ser Leu Thr Glu Glu Met Ala Ser Thr Asp Leu Asp Ile 
465                 470                 475                 480 


Ser Ser Pro Ser Ser Pro Met Ser Thr Phe Ala Ile Phe Pro Pro Met 
                485                 490                 495     


Ser Thr Pro Ser His Glu Leu Ser Lys Ser Glu Ala Asp Thr Ser Ala 
            500                 505                 510         


Ile Arg Asn Thr Asp Ser Thr Thr Leu Asp Gln His Leu Gly Ile Arg 
        515                 520                 525             


Ser Leu Gly Arg Thr Gly Asp Leu Thr Thr Val Pro Ile Thr Pro Leu 
    530                 535                 540                 


Thr Thr Thr Trp Thr Ser Val Ile Glu His Ser Thr Gln Ala Gln Asp 
545                 550                 555                 560 


Thr Leu Ser Ala Thr Met Ser Pro Thr His Val Thr Gln Ser Leu Lys 
                565                 570                 575     


Asp Gln Thr Ser Ile Pro Ala Ser Ala Ser Pro Ser His Leu Thr Glu 
            580                 585                 590         


Val Tyr Pro Glu Leu Gly Thr Gln Gly Arg Ser Ser Ser Glu Ala Thr 
        595                 600                 605             


Thr Phe Trp Lys Pro Ser Thr Asp Thr Leu Ser Arg Glu Ile Glu Thr 
    610                 615                 620                 


Gly Pro Thr Asn Ile Gln Ser Thr Pro Pro Met Asp Asn Thr Thr Thr 
625                 630                 635                 640 


Gly Ser Ser Ser Ser Gly Val Thr Leu Gly Ile Ala His Leu Pro Ile 
                645                 650                 655     


Gly Thr Ser Ser Pro Ala Glu Thr Ser Thr Asn Met Ala Leu Glu Arg 
            660                 665                 670         


Arg Ser Ser Thr Ala Thr Val Ser Met Ala Gly Thr Met Gly Leu Leu 
        675                 680                 685             


Val Thr Ser Ala Pro Gly Arg Ser Ile Ser Gln Ser Leu Gly Arg Val 
    690                 695                 700                 


Ser Ser Val Leu Ser Glu Ser Thr Thr Glu Gly Val Thr Asp Ser Ser 
705                 710                 715                 720 


Lys Gly Ser Ser Pro Arg Leu Asn Thr Gln Gly Asn Thr Ala Leu Ser 
                725                 730                 735     


Ser Ser Leu Glu Pro Ser Tyr Ala Glu Gly Ser Gln Met Ser Thr Ser 
            740                 745                 750         


Ile Pro Leu Thr Ser Ser Pro Thr Thr Pro Asp Val Glu Phe Ile Gly 
        755                 760                 765             


Gly Ser Thr Phe Trp Thr Lys Glu Val Thr Thr Val Met Thr Ser Asp 
    770                 775                 780                 


Ile Ser Lys Ser Ser Ala Arg Thr Glu Ser Ser Ser Ala Thr Leu Met 
785                 790                 795                 800 


Ser Thr Ala Leu Gly Ser Thr Glu Asn Thr Gly Lys Glu Lys Leu Arg 
                805                 810                 815     


Thr Ala Ser Met Asp Leu Pro Ser Pro Thr Pro Ser Met Glu Val Thr 
            820                 825                 830         


Pro Trp Ile Ser Leu Thr Leu Ser Asn Ala Pro Asn Thr Thr Asp Ser 
        835                 840                 845             


Leu Asp Leu Ser His Gly Val His Thr Ser Ser Ala Gly Thr Leu Ala 
    850                 855                 860                 


Thr Asp Arg Ser Leu Asn Thr Gly Val Thr Arg Ala Ser Arg Leu Glu 
865                 870                 875                 880 


Asn Gly Ser Asp Thr Ser Ser Lys Ser Leu Ser Met Gly Asn Ser Thr 
                885                 890                 895     


His Thr Ser Met Thr Tyr Thr Glu Lys Ser Glu Val Ser Ser Ser Ile 
            900                 905                 910         


His Pro Arg Pro Glu Thr Ser Ala Pro Gly Ala Glu Thr Thr Leu Thr 
        915                 920                 925             


Ser Thr Pro Gly Asn Arg Ala Ile Ser Leu Thr Leu Pro Phe Ser Ser 
    930                 935                 940                 


Ile Pro Val Glu Glu Val Ile Ser Thr Gly Ile Thr Ser Gly Pro Asp 
945                 950                 955                 960 


Ile Asn Ser Ala Pro Met Thr His Ser Pro Ile Thr Pro Pro Thr Ile 
                965                 970                 975     


Val Trp Thr Ser Thr Gly Thr Ile Glu Gln Ser Thr Gln Pro Leu His 
            980                 985                 990         


Ala Val Ser Ser Glu Lys Val Ser  Val Gln Thr Gln Ser  Thr Pro Tyr 
        995                 1000                 1005             


Val Asn  Ser Val Ala Val Ser  Ala Ser Pro Thr His  Glu Asn Ser 
    1010                 1015                 1020             


Val Ser  Ser Gly Ser Ser Thr  Ser Ser Pro Tyr Ser  Ser Ala Ser 
    1025                 1030                 1035             


Leu Glu  Ser Leu Asp Ser Thr  Ile Ser Arg Arg Asn  Ala Ile Thr 
    1040                 1045                 1050             


Ser Trp  Leu Trp Asp Leu Thr  Thr Ser Leu Pro Thr  Thr Thr Trp 
    1055                 1060                 1065             


Pro Ser  Thr Ser Leu Ser Glu  Ala Leu Ser Ser Gly  His Ser Gly 
    1070                 1075                 1080             


Val Ser  Asn Pro Ser Ser Thr  Thr Thr Glu Phe Pro  Leu Phe Ser 
    1085                 1090                 1095             


Ala Ala  Ser Thr Ser Ala Ala  Lys Gln Arg Asn Pro  Glu Thr Glu 
    1100                 1105                 1110             


Thr His  Gly Pro Gln Asn Thr  Ala Ala Ser Thr Leu  Asn Thr Asp 
    1115                 1120                 1125             


Ala Ser  Ser Val Thr Gly Leu  Ser Glu Thr Pro Val  Gly Ala Ser 
    1130                 1135                 1140             


Ile Ser  Ser Glu Val Pro Leu  Pro Met Ala Ile Thr  Ser Arg Ser 
    1145                 1150                 1155             


Asp Val  Ser Gly Leu Thr Ser  Glu Ser Thr Ala Asn  Pro Ser Leu 
    1160                 1165                 1170             


Gly Thr  Ala Ser Ser Ala Gly  Thr Lys Leu Thr Arg  Thr Ile Ser 
    1175                 1180                 1185             


Leu Pro  Thr Ser Glu Ser Leu  Val Ser Phe Arg Met  Asn Lys Asp 
    1190                 1195                 1200             


Pro Trp  Thr Val Ser Ile Pro  Leu Gly Ser His Pro  Thr Thr Asn 
    1205                 1210                 1215             


Thr Glu  Thr Ser Ile Pro Val  Asn Ser Ala Gly Pro  Pro Gly Leu 
    1220                 1225                 1230             


Ser Thr  Val Ala Ser Asp Val  Ile Asp Thr Pro Ser  Asp Gly Ala 
    1235                 1240                 1245             


Glu Ser  Ile Pro Thr Val Ser  Phe Ser Pro Ser Pro  Asp Thr Glu 
    1250                 1255                 1260             


Val Thr  Thr Ile Ser His Phe  Pro Glu Lys Thr Thr  His Ser Phe 
    1265                 1270                 1275             


Arg Thr  Ile Ser Ser Leu Thr  His Glu Leu Thr Ser  Arg Val Thr 
    1280                 1285                 1290             


Pro Ile  Pro Gly Asp Trp Met  Ser Ser Ala Met Ser  Thr Lys Pro 
    1295                 1300                 1305             


Thr Gly  Ala Ser Pro Ser Ile  Thr Leu Gly Glu Arg  Arg Thr Ile 
    1310                 1315                 1320             


Thr Ser  Ala Ala Pro Thr Thr  Ser Pro Ile Val Leu  Thr Ala Ser 
    1325                 1330                 1335             


Phe Thr  Glu Thr Ser Thr Val  Ser Leu Asp Asn Glu  Thr Thr Val 
    1340                 1345                 1350             


Lys Thr  Ser Asp Ile Leu Asp  Ala Arg Lys Thr Asn  Glu Leu Pro 
    1355                 1360                 1365             


Ser Asp  Ser Ser Ser Ser Ser  Asp Leu Ile Asn Thr  Ser Ile Ala 
    1370                 1375                 1380             


Ser Ser  Thr Met Asp Val Thr  Lys Thr Ala Ser Ile  Ser Pro Thr 
    1385                 1390                 1395             


Ser Ile  Ser Gly Met Thr Ala  Ser Ser Ser Pro Ser  Leu Phe Ser 
    1400                 1405                 1410             


Ser Asp  Arg Pro Gln Val Pro  Thr Ser Thr Thr Glu  Thr Asn Thr 
    1415                 1420                 1425             


Ala Thr  Ser Pro Ser Val Ser  Ser Asn Thr Tyr Ser  Leu Asp Gly 
    1430                 1435                 1440             


Gly Ser  Asn Val Gly Gly Thr  Pro Ser Thr Leu Pro  Pro Phe Thr 
    1445                 1450                 1455             


Ile Thr  His Pro Val Glu Thr  Ser Ser Ala Leu Leu  Ala Trp Ser 
    1460                 1465                 1470             


Arg Pro  Val Arg Thr Phe Ser  Thr Met Val Ser Thr  Asp Thr Ala 
    1475                 1480                 1485             


Ser Gly  Glu Asn Pro Thr Ser  Ser Asn Ser Val Val  Thr Ser Val 
    1490                 1495                 1500             


Pro Ala  Pro Gly Thr Trp Thr  Ser Val Gly Ser Thr  Thr Asp Leu 
    1505                 1510                 1515             


Pro Ala  Met Gly Phe Leu Lys  Thr Ser Pro Ala Gly  Glu Ala His 
    1520                 1525                 1530             


Ser Leu  Leu Ala Ser Thr Ile  Glu Pro Ala Thr Ala  Phe Thr Pro 
    1535                 1540                 1545             


His Leu  Ser Ala Ala Val Val  Thr Gly Ser Ser Ala  Thr Ser Glu 
    1550                 1555                 1560             


Ala Ser  Leu Leu Thr Thr Ser  Glu Ser Lys Ala Ile  His Ser Ser 
    1565                 1570                 1575             


Pro Gln  Thr Pro Thr Thr Pro  Thr Ser Gly Ala Asn  Trp Glu Thr 
    1580                 1585                 1590             


Ser Ala  Thr Pro Glu Ser Leu  Leu Val Val Thr Glu  Thr Ser Asp 
    1595                 1600                 1605             


Thr Thr  Leu Thr Ser Lys Ile  Leu Val Thr Asp Thr  Ile Leu Phe 
    1610                 1615                 1620             


Ser Thr  Val Ser Thr Pro Pro  Ser Lys Phe Pro Ser  Thr Gly Thr 
    1625                 1630                 1635             


Leu Ser  Gly Ala Ser Phe Pro  Thr Leu Leu Pro Asp  Thr Pro Ala 
    1640                 1645                 1650             


Ile Pro  Leu Thr Ala Thr Glu  Pro Thr Ser Ser Leu  Ala Thr Ser 
    1655                 1660                 1665             


Phe Asp  Ser Thr Pro Leu Val  Thr Ile Ala Ser Asp  Ser Leu Gly 
    1670                 1675                 1680             


Thr Val  Pro Glu Thr Thr Leu  Thr Met Ser Glu Thr  Ser Asn Gly 
    1685                 1690                 1695             


Asp Ala  Leu Val Leu Lys Thr  Val Ser Asn Pro Asp  Arg Ser Ile 
    1700                 1705                 1710             


Pro Gly  Ile Thr Ile Gln Gly  Val Thr Glu Ser Pro  Leu His Pro 
    1715                 1720                 1725             


Ser Ser  Thr Ser Pro Ser Lys  Ile Val Ala Pro Arg  Asn Thr Thr 
    1730                 1735                 1740             


Tyr Glu  Gly Ser Ile Thr Val  Ala Leu Ser Thr Leu  Pro Ala Gly 
    1745                 1750                 1755             


Thr Thr  Gly Ser Leu Val Phe  Ser Gln Ser Ser Glu  Asn Ser Glu 
    1760                 1765                 1770             


Thr Thr  Ala Leu Val Asp Ser  Ser Ala Gly Leu Glu  Arg Ala Ser 
    1775                 1780                 1785             


Val Met  Pro Leu Thr Thr Gly  Ser Gln Gly Met Ala  Ser Ser Gly 
    1790                 1795                 1800             


Gly Ile  Arg Ser Gly Ser Thr  His Ser Thr Gly Thr  Lys Thr Phe 
    1805                 1810                 1815             


Ser Ser  Leu Pro Leu Thr Met  Asn Pro Gly Glu Val  Thr Ala Met 
    1820                 1825                 1830             


Ser Glu  Ile Thr Thr Asn Arg  Leu Thr Ala Thr Gln  Ser Thr Ala 
    1835                 1840                 1845             


Pro Lys  Gly Ile Pro Val Lys  Pro Thr Ser Ala Glu  Ser Gly Leu 
    1850                 1855                 1860             


Leu Thr  Pro Val Ser Ala Ser  Ser Ser Pro Ser Lys  Ala Phe Ala 
    1865                 1870                 1875             


Ser Leu  Thr Thr Ala Pro Pro  Thr Trp Gly Ile Pro  Gln Ser Thr 
    1880                 1885                 1890             


Leu Thr  Phe Glu Phe Ser Glu  Val Pro Ser Leu Asp  Thr Lys Ser 
    1895                 1900                 1905             


Ala Ser  Leu Pro Thr Pro Gly  Gln Ser Leu Asn Thr  Ile Pro Asp 
    1910                 1915                 1920             


Ser Asp  Ala Ser Thr Ala Ser  Ser Ser Leu Ser Lys  Ser Pro Glu 
    1925                 1930                 1935             


Lys Asn  Pro Arg Ala Arg Met  Met Thr Ser Thr Lys  Ala Ile Ser 
    1940                 1945                 1950             


Ala Ser  Ser Phe Gln Ser Thr  Gly Phe Thr Glu Thr  Pro Glu Gly 
    1955                 1960                 1965             


Ser Ala  Ser Pro Ser Met Ala  Gly His Glu Pro Arg  Val Pro Thr 
    1970                 1975                 1980             


Ser Gly  Thr Gly Asp Pro Arg  Tyr Ala Ser Glu Ser  Met Ser Tyr 
    1985                 1990                 1995             


Pro Asp  Pro Ser Lys Ala Ser  Ser Ala Met Thr Ser  Thr Ser Leu 
    2000                 2005                 2010             


Ala Ser  Lys Leu Thr Thr Leu  Phe Ser Thr Gly Gln  Ala Ala Arg 
    2015                 2020                 2025             


Ser Gly  Ser Ser Ser Ser Pro  Ile Ser Leu Ser Thr  Glu Lys Glu 
    2030                 2035                 2040             


Thr Ser  Phe Leu Ser Pro Thr  Ala Ser Thr Ser Arg  Lys Thr Ser 
    2045                 2050                 2055             


Leu Phe  Leu Gly Pro Ser Met  Ala Arg Gln Pro Asn  Ile Leu Val 
    2060                 2065                 2070             


His Leu  Gln Thr Ser Ala Leu  Thr Leu Ser Pro Thr  Ser Thr Leu 
    2075                 2080                 2085             


Asn Met  Ser Gln Glu Glu Pro  Pro Glu Leu Thr Ser  Ser Gln Thr 
    2090                 2095                 2100             


Ile Ala  Glu Glu Glu Gly Thr  Thr Ala Glu Thr Gln  Thr Leu Thr 
    2105                 2110                 2115             


Phe Thr  Pro Ser Glu Thr Pro  Thr Ser Leu Leu Pro  Val Ser Ser 
    2120                 2125                 2130             


Pro Thr  Glu Pro Thr Ala Arg  Arg Lys Ser Ser Pro  Glu Thr Trp 
    2135                 2140                 2145             


Ala Ser  Ser Ile Ser Val Pro  Ala Lys Thr Ser Leu  Val Glu Thr 
    2150                 2155                 2160             


Thr Asp  Gly Thr Leu Val Thr  Thr Ile Lys Met Ser  Ser Gln Ala 
    2165                 2170                 2175             


Ala Gln  Gly Asn Ser Thr Trp  Pro Ala Pro Ala Glu  Glu Thr Gly 
    2180                 2185                 2190             


Ser Ser  Pro Ala Gly Thr Ser  Pro Gly Ser Pro Glu  Met Ser Thr 
    2195                 2200                 2205             


Thr Leu  Lys Ile Met Ser Ser  Lys Glu Pro Ser Ile  Ser Pro Glu 
    2210                 2215                 2220             


Ile Arg  Ser Thr Val Arg Asn  Ser Pro Trp Lys Thr  Pro Glu Thr 
    2225                 2230                 2235             


Thr Val  Pro Met Glu Thr Thr  Val Glu Pro Val Thr  Leu Gln Ser 
    2240                 2245                 2250             


Thr Ala  Leu Gly Ser Gly Ser  Thr Ser Ile Ser His  Leu Pro Thr 
    2255                 2260                 2265             


Gly Thr  Thr Ser Pro Thr Lys  Ser Pro Thr Glu Asn  Met Leu Ala 
    2270                 2275                 2280             


Thr Glu  Arg Val Ser Leu Ser  Pro Ser Pro Pro Glu  Ala Trp Thr 
    2285                 2290                 2295             


Asn Leu  Tyr Ser Gly Thr Pro  Gly Gly Thr Arg Gln  Ser Leu Ala 
    2300                 2305                 2310             


Thr Met  Ser Ser Val Ser Leu  Glu Ser Pro Thr Ala  Arg Ser Ile 
    2315                 2320                 2325             


Thr Gly  Thr Gly Gln Gln Ser  Ser Pro Glu Leu Val  Ser Lys Thr 
    2330                 2335                 2340             


Thr Gly  Met Glu Phe Ser Met  Trp His Gly Ser Thr  Gly Gly Thr 
    2345                 2350                 2355             


Thr Gly  Asp Thr His Val Ser  Leu Ser Thr Ser Ser  Asn Ile Leu 
    2360                 2365                 2370             


Glu Asp  Pro Val Thr Ser Pro  Asn Ser Val Ser Ser  Leu Thr Asp 
    2375                 2380                 2385             


Lys Ser  Lys His Lys Thr Glu  Thr Trp Val Ser Thr  Thr Ala Ile 
    2390                 2395                 2400             


Pro Ser  Thr Val Leu Asn Asn  Lys Ile Met Ala Ala  Glu Gln Gln 
    2405                 2410                 2415             


Thr Ser  Arg Ser Val Asp Glu  Ala Tyr Ser Ser Thr  Ser Ser Trp 
    2420                 2425                 2430             


Ser Asp  Gln Thr Ser Gly Ser  Asp Ile Thr Leu Gly  Ala Ser Pro 
    2435                 2440                 2445             


Asp Val  Thr Asn Thr Leu Tyr  Ile Thr Ser Thr Ala  Gln Thr Thr 
    2450                 2455                 2460             


Ser Leu  Val Ser Leu Pro Ser  Gly Asp Gln Gly Ile  Thr Ser Leu 
    2465                 2470                 2475             


Thr Asn  Pro Ser Gly Gly Lys  Thr Ser Ser Ala Ser  Ser Val Thr 
    2480                 2485                 2490             


Ser Pro  Ser Ile Gly Leu Glu  Thr Leu Arg Ala Asn  Val Ser Ala 
    2495                 2500                 2505             


Val Lys  Ser Asp Ile Ala Pro  Thr Ala Gly His Leu  Ser Gln Thr 
    2510                 2515                 2520             


Ser Ser  Pro Ala Glu Val Ser  Ile Leu Asp Val Thr  Thr Ala Pro 
    2525                 2530                 2535             


Thr Pro  Gly Ile Ser Thr Thr  Ile Thr Thr Met Gly  Thr Asn Ser 
    2540                 2545                 2550             


Ile Ser  Thr Thr Thr Pro Asn  Pro Glu Val Gly Met  Ser Thr Met 
    2555                 2560                 2565             


Asp Ser  Thr Pro Ala Thr Glu  Arg Arg Thr Thr Ser  Thr Glu His 
    2570                 2575                 2580             


Pro Ser  Thr Trp Ser Ser Thr  Ala Ala Ser Asp Ser  Trp Thr Val 
    2585                 2590                 2595             


Thr Asp  Met Thr Ser Asn Leu  Lys Val Ala Arg Ser  Pro Gly Thr 
    2600                 2605                 2610             


Ile Ser  Thr Met His Thr Thr  Ser Phe Leu Ala Ser  Ser Thr Glu 
    2615                 2620                 2625             


Leu Asp  Ser Met Ser Thr Pro  His Gly Arg Ile Thr  Val Ile Gly 
    2630                 2635                 2640             


Thr Ser  Leu Val Thr Pro Ser  Ser Asp Ala Ser Ala  Val Lys Thr 
    2645                 2650                 2655             


Glu Thr  Ser Thr Ser Glu Arg  Thr Leu Ser Pro Ser  Asp Thr Thr 
    2660                 2665                 2670             


Ala Ser  Thr Pro Ile Ser Thr  Phe Ser Arg Val Gln  Arg Met Ser 
    2675                 2680                 2685             


Ile Ser  Val Pro Asp Ile Leu  Ser Thr Ser Trp Thr  Pro Ser Ser 
    2690                 2695                 2700             


Thr Glu  Ala Glu Asp Val Pro  Val Ser Met Val Ser  Thr Asp His 
    2705                 2710                 2715             


Ala Ser  Thr Lys Thr Asp Pro  Asn Thr Pro Leu Ser  Thr Phe Leu 
    2720                 2725                 2730             


Phe Asp  Ser Leu Ser Thr Leu  Asp Trp Asp Thr Gly  Arg Ser Leu 
    2735                 2740                 2745             


Ser Ser  Ala Thr Ala Thr Thr  Ser Ala Pro Gln Gly  Ala Thr Thr 
    2750                 2755                 2760             


Pro Gln  Glu Leu Thr Leu Glu  Thr Met Ile Ser Pro  Ala Thr Ser 
    2765                 2770                 2775             


Gln Leu  Pro Phe Ser Ile Gly  His Ile Thr Ser Ala  Val Thr Pro 
    2780                 2785                 2790             


Ala Ala  Met Ala Arg Ser Ser  Gly Val Thr Phe Ser  Arg Pro Asp 
    2795                 2800                 2805             


Pro Thr  Ser Lys Lys Ala Glu  Gln Thr Ser Thr Gln  Leu Pro Thr 
    2810                 2815                 2820             


Thr Thr  Ser Ala His Pro Gly  Gln Val Pro Arg Ser  Ala Ala Thr 
    2825                 2830                 2835             


Thr Leu  Asp Val Ile Pro His  Thr Ala Lys Thr Pro  Asp Ala Thr 
    2840                 2845                 2850             


Phe Gln  Arg Gln Gly Gln Thr  Ala Leu Thr Thr Glu  Ala Arg Ala 
    2855                 2860                 2865             


Thr Ser  Asp Ser Trp Asn Glu  Lys Glu Lys Ser Thr  Pro Ser Ala 
    2870                 2875                 2880             


Pro Trp  Ile Thr Glu Met Met  Asn Ser Val Ser Glu  Asp Thr Ile 
    2885                 2890                 2895             


Lys Glu  Val Thr Ser Ser Ser  Ser Val Leu Arg Thr  Leu Asn Thr 
    2900                 2905                 2910             


Leu Asp  Ile Asn Leu Glu Ser  Gly Thr Thr Ser Ser  Pro Ser Trp 
    2915                 2920                 2925             


Lys Ser  Ser Pro Tyr Glu Arg  Ile Ala Pro Ser Glu  Ser Thr Thr 
    2930                 2935                 2940             


Asp Lys  Glu Ala Ile His Pro  Ser Thr Asn Thr Val  Glu Thr Thr 
    2945                 2950                 2955             


Gly Trp  Val Thr Ser Ser Glu  His Ala Ser His Ser  Thr Ile Pro 
    2960                 2965                 2970             


Ala His  Ser Ala Ser Ser Lys  Leu Thr Ser Pro Val  Val Thr Thr 
    2975                 2980                 2985             


Ser Thr  Arg Glu Gln Ala Ile  Val Ser Met Ser Thr  Thr Thr Trp 
    2990                 2995                 3000             


Pro Glu  Ser Thr Arg Ala Arg  Thr Glu Pro Asn Ser  Phe Leu Thr 
    3005                 3010                 3015             


Ile Glu  Leu Arg Asp Val Ser  Pro Tyr Met Asp Thr  Ser Ser Thr 
    3020                 3025                 3030             


Thr Gln  Thr Ser Ile Ile Ser  Ser Pro Gly Ser Thr  Ala Ile Thr 
    3035                 3040                 3045             


Lys Gly  Pro Arg Thr Glu Ile  Thr Ser Ser Lys Arg  Ile Ser Ser 
    3050                 3055                 3060             


Ser Phe  Leu Ala Gln Ser Met  Arg Ser Ser Asp Ser  Pro Ser Glu 
    3065                 3070                 3075             


Ala Ile  Thr Arg Leu Ser Asn  Phe Pro Ala Met Thr  Glu Ser Gly 
    3080                 3085                 3090             


Gly Met  Ile Leu Ala Met Gln  Thr Ser Pro Pro Gly  Ala Thr Ser 
    3095                 3100                 3105             


Leu Ser  Ala Pro Thr Leu Asp  Thr Ser Ala Thr Ala  Ser Trp Thr 
    3110                 3115                 3120             


Gly Thr  Pro Leu Ala Thr Thr  Gln Arg Phe Thr Tyr  Ser Glu Lys 
    3125                 3130                 3135             


Thr Thr  Leu Phe Ser Lys Gly  Pro Glu Asp Thr Ser  Gln Pro Ser 
    3140                 3145                 3150             


Pro Pro  Ser Val Glu Glu Thr  Ser Ser Ser Ser Ser  Leu Val Pro 
    3155                 3160                 3165             


Ile His  Ala Thr Thr Ser Pro  Ser Asn Ile Leu Leu  Thr Ser Gln 
    3170                 3175                 3180             


Gly His  Ser Pro Ser Ser Thr  Pro Pro Val Thr Ser  Val Phe Leu 
    3185                 3190                 3195             


Ser Glu  Thr Ser Gly Leu Gly  Lys Thr Thr Asp Met  Ser Arg Ile 
    3200                 3205                 3210             


Ser Leu  Glu Pro Gly Thr Ser  Leu Pro Pro Asn Leu  Ser Ser Thr 
    3215                 3220                 3225             


Ala Gly  Glu Ala Leu Ser Thr  Tyr Glu Ala Ser Arg  Asp Thr Lys 
    3230                 3235                 3240             


Ala Ile  His His Ser Ala Asp  Thr Ala Val Thr Asn  Met Glu Ala 
    3245                 3250                 3255             


Thr Ser  Ser Glu Tyr Ser Pro  Ile Pro Gly His Thr  Lys Pro Ser 
    3260                 3265                 3270             


Lys Ala  Thr Ser Pro Leu Val  Thr Ser His Ile Met  Gly Asp Ile 
    3275                 3280                 3285             


Thr Ser  Ser Thr Ser Val Phe  Gly Ser Ser Glu Thr  Thr Glu Ile 
    3290                 3295                 3300             


Glu Thr  Val Ser Ser Val Asn  Gln Gly Leu Gln Glu  Arg Ser Thr 
    3305                 3310                 3315             


Ser Gln  Val Ala Ser Ser Ala  Thr Glu Thr Ser Thr  Val Ile Thr 
    3320                 3325                 3330             


His Val  Ser Ser Gly Asp Ala  Thr Thr His Val Thr  Lys Thr Gln 
    3335                 3340                 3345             


Ala Thr  Phe Ser Ser Gly Thr  Ser Ile Ser Ser Pro  His Gln Phe 
    3350                 3355                 3360             


Ile Thr  Ser Thr Asn Thr Phe  Thr Asp Val Ser Thr  Asn Pro Ser 
    3365                 3370                 3375             


Thr Ser  Leu Ile Met Thr Glu  Ser Ser Gly Val Thr  Ile Thr Thr 
    3380                 3385                 3390             


Gln Thr  Gly Pro Thr Gly Ala  Ala Thr Gln Gly Pro  Tyr Leu Leu 
    3395                 3400                 3405             


Asp Thr  Ser Thr Met Pro Tyr  Leu Thr Glu Thr Pro  Leu Ala Val 
    3410                 3415                 3420             


Thr Pro  Asp Phe Met Gln Ser  Glu Lys Thr Thr Leu  Ile Ser Lys 
    3425                 3430                 3435             


Gly Pro  Lys Asp Val Ser Trp  Thr Ser Pro Pro Ser  Val Ala Glu 
    3440                 3445                 3450             


Thr Ser  Tyr Pro Ser Ser Leu  Thr Pro Phe Leu Val  Thr Thr Ile 
    3455                 3460                 3465             


Pro Pro  Ala Thr Ser Thr Leu  Gln Gly Gln His Thr  Ser Ser Pro 
    3470                 3475                 3480             


Val Ser  Ala Thr Ser Val Leu  Thr Ser Gly Leu Val  Lys Thr Thr 
    3485                 3490                 3495             


Asp Met  Leu Asn Thr Ser Met  Glu Pro Val Thr Asn  Ser Pro Gln 
    3500                 3505                 3510             


Asn Leu  Asn Asn Pro Ser Asn  Glu Ile Leu Ala Thr  Leu Ala Ala 
    3515                 3520                 3525             


Thr Thr  Asp Ile Glu Thr Ile  His Pro Ser Ile Asn  Lys Ala Val 
    3530                 3535                 3540             


Thr Asn  Met Gly Thr Ala Ser  Ser Ala His Val Leu  His Ser Thr 
    3545                 3550                 3555             


Leu Pro  Val Ser Ser Glu Pro  Ser Thr Ala Thr Ser  Pro Met Val 
    3560                 3565                 3570             


Pro Ala  Ser Ser Met Gly Asp  Ala Leu Ala Ser Ile  Ser Ile Pro 
    3575                 3580                 3585             


Gly Ser  Glu Thr Thr Asp Ile  Glu Gly Glu Pro Thr  Ser Ser Leu 
    3590                 3595                 3600             


Thr Ala  Gly Arg Lys Glu Asn  Ser Thr Leu Gln Glu  Met Asn Ser 
    3605                 3610                 3615             


Thr Thr  Glu Ser Asn Ile Ile  Leu Ser Asn Val Ser  Val Gly Ala 
    3620                 3625                 3630             


Ile Thr  Glu Ala Thr Lys Met  Glu Val Pro Ser Phe  Asp Ala Thr 
    3635                 3640                 3645             


Phe Ile  Pro Thr Pro Ala Gln  Ser Thr Lys Phe Pro  Asp Ile Phe 
    3650                 3655                 3660             


Ser Val  Ala Ser Ser Arg Leu  Ser Asn Ser Pro Pro  Met Thr Ile 
    3665                 3670                 3675             


Ser Thr  His Met Thr Thr Thr  Gln Thr Gly Ser Ser  Gly Ala Thr 
    3680                 3685                 3690             


Ser Lys  Ile Pro Leu Ala Leu  Asp Thr Ser Thr Leu  Glu Thr Ser 
    3695                 3700                 3705             


Ala Gly  Thr Pro Ser Val Val  Thr Glu Gly Phe Ala  His Ser Lys 
    3710                 3715                 3720             


Ile Thr  Thr Ala Met Asn Asn  Asp Val Lys Asp Val  Ser Gln Thr 
    3725                 3730                 3735             


Asn Pro  Pro Phe Gln Asp Glu  Ala Ser Ser Pro Ser  Ser Gln Ala 
    3740                 3745                 3750             


Pro Val  Leu Val Thr Thr Leu  Pro Ser Ser Val Ala  Phe Thr Pro 
    3755                 3760                 3765             


Gln Trp  His Ser Thr Ser Ser  Pro Val Ser Met Ser  Ser Val Leu 
    3770                 3775                 3780             


Thr Ser  Ser Leu Val Lys Thr  Ala Gly Lys Val Asp  Thr Ser Leu 
    3785                 3790                 3795             


Glu Thr  Val Thr Ser Ser Pro  Gln Ser Met Ser Asn  Thr Leu Asp 
    3800                 3805                 3810             


Asp Ile  Ser Val Thr Ser Ala  Ala Thr Thr Asp Ile  Glu Thr Thr 
    3815                 3820                 3825             


His Pro  Ser Ile Asn Thr Val  Val Thr Asn Val Gly  Thr Thr Gly 
    3830                 3835                 3840             


Ser Ala  Phe Glu Ser His Ser  Thr Val Ser Ala Tyr  Pro Glu Pro 
    3845                 3850                 3855             


Ser Lys  Val Thr Ser Pro Asn  Val Thr Thr Ser Thr  Met Glu Asp 
    3860                 3865                 3870             


Thr Thr  Ile Ser Arg Ser Ile  Pro Lys Ser Ser Lys  Thr Thr Arg 
    3875                 3880                 3885             


Thr Glu  Thr Glu Thr Thr Ser  Ser Leu Thr Pro Lys  Leu Arg Glu 
    3890                 3895                 3900             


Thr Ser  Ile Ser Gln Glu Ile  Thr Ser Ser Thr Glu  Thr Ser Thr 
    3905                 3910                 3915             


Val Pro  Tyr Lys Glu Leu Thr  Gly Ala Thr Thr Glu  Val Ser Arg 
    3920                 3925                 3930             


Thr Asp  Val Thr Ser Ser Ser  Ser Thr Ser Phe Pro  Gly Pro Asp 
    3935                 3940                 3945             


Gln Ser  Thr Val Ser Leu Asp  Ile Ser Thr Glu Thr  Asn Thr Arg 
    3950                 3955                 3960             


Leu Ser  Thr Ser Pro Ile Met  Thr Glu Ser Ala Glu  Ile Thr Ile 
    3965                 3970                 3975             


Thr Thr  Gln Thr Gly Pro His  Gly Ala Thr Ser Gln  Asp Thr Phe 
    3980                 3985                 3990             


Thr Met  Asp Pro Ser Asn Thr  Thr Pro Gln Ala Gly  Ile His Ser 
    3995                 4000                 4005             


Ala Met  Thr His Gly Phe Ser  Gln Leu Asp Val Thr  Thr Leu Met 
    4010                 4015                 4020             


Ser Arg  Ile Pro Gln Asp Val  Ser Trp Thr Ser Pro  Pro Ser Val 
    4025                 4030                 4035             


Asp Lys  Thr Ser Ser Pro Ser  Ser Phe Leu Ser Ser  Pro Ala Met 
    4040                 4045                 4050             


Thr Thr  Pro Ser Leu Ile Ser  Ser Thr Leu Pro Glu  Asp Lys Leu 
    4055                 4060                 4065             


Ser Ser  Pro Met Thr Ser Leu  Leu Thr Ser Gly Leu  Val Lys Ile 
    4070                 4075                 4080             


Thr Asp  Ile Leu Arg Thr Arg  Leu Glu Pro Val Thr  Ser Ser Leu 
    4085                 4090                 4095             


Pro Asn  Phe Ser Ser Thr Ser  Asp Lys Ile Leu Ala  Thr Ser Lys 
    4100                 4105                 4110             


Asp Ser  Lys Asp Thr Lys Glu  Ile Phe Pro Ser Ile  Asn Thr Glu 
    4115                 4120                 4125             


Glu Thr  Asn Val Lys Ala Asn  Asn Ser Gly His Glu  Ser His Ser 
    4130                 4135                 4140             


Pro Ala  Leu Ala Asp Ser Glu  Thr Pro Lys Ala Thr  Thr Gln Met 
    4145                 4150                 4155             


Val Ile  Thr Thr Thr Val Gly  Asp Pro Ala Pro Ser  Thr Ser Met 
    4160                 4165                 4170             


Pro Val  His Gly Ser Ser Glu  Thr Thr Asn Ile Lys  Arg Glu Pro 
    4175                 4180                 4185             


Thr Tyr  Phe Leu Thr Pro Arg  Leu Arg Glu Thr Ser  Thr Ser Gln 
    4190                 4195                 4200             


Glu Ser  Ser Phe Pro Thr Asp  Thr Ser Phe Leu Leu  Ser Lys Val 
    4205                 4210                 4215             


Pro Thr  Gly Thr Ile Thr Glu  Val Ser Ser Thr Gly  Val Asn Ser 
    4220                 4225                 4230             


Ser Ser  Lys Ile Ser Thr Pro  Asp His Asp Lys Ser  Thr Val Pro 
    4235                 4240                 4245             


Pro Asp  Thr Phe Thr Gly Glu  Ile Pro Arg Val Phe  Thr Ser Ser 
    4250                 4255                 4260             


Ile Lys  Thr Lys Ser Ala Glu  Met Thr Ile Thr Thr  Gln Ala Ser 
    4265                 4270                 4275             


Pro Pro  Glu Ser Ala Ser His  Ser Thr Leu Pro Leu  Asp Thr Ser 
    4280                 4285                 4290             


Thr Thr  Leu Ser Gln Gly Gly  Thr His Ser Thr Val  Thr Gln Gly 
    4295                 4300                 4305             


Phe Pro  Tyr Ser Glu Val Thr  Thr Leu Met Gly Met  Gly Pro Gly 
    4310                 4315                 4320             


Asn Val  Ser Trp Met Thr Thr  Pro Pro Val Glu Glu  Thr Ser Ser 
    4325                 4330                 4335             


Val Ser  Ser Leu Met Ser Ser  Pro Ala Met Thr Ser  Pro Ser Pro 
    4340                 4345                 4350             


Val Ser  Ser Thr Ser Pro Gln  Ser Ile Pro Ser Ser  Pro Leu Pro 
    4355                 4360                 4365             


Val Thr  Ala Leu Pro Thr Ser  Val Leu Val Thr Thr  Thr Asp Val 
    4370                 4375                 4380             


Leu Gly  Thr Thr Ser Pro Glu  Ser Val Thr Ser Ser  Pro Pro Asn 
    4385                 4390                 4395             


Leu Ser  Ser Ile Thr His Glu  Arg Pro Ala Thr Tyr  Lys Asp Thr 
    4400                 4405                 4410             


Ala His  Thr Glu Ala Ala Met  His His Ser Thr Asn  Thr Ala Val 
    4415                 4420                 4425             


Thr Asn  Val Gly Thr Ser Gly  Ser Gly His Lys Ser  Gln Ser Ser 
    4430                 4435                 4440             


Val Leu  Ala Asp Ser Glu Thr  Ser Lys Ala Thr Pro  Leu Met Ser 
    4445                 4450                 4455             


Thr Thr  Ser Thr Leu Gly Asp  Thr Ser Val Ser Thr  Ser Thr Pro 
    4460                 4465                 4470             


Asn Ile  Ser Gln Thr Asn Gln  Ile Gln Thr Glu Pro  Thr Ala Ser 
    4475                 4480                 4485             


Leu Ser  Pro Arg Leu Arg Glu  Ser Ser Thr Ser Glu  Lys Thr Ser 
    4490                 4495                 4500             


Ser Thr  Thr Glu Thr Asn Thr  Ala Phe Ser Tyr Val  Pro Thr Gly 
    4505                 4510                 4515             


Ala Ile  Thr Gln Ala Ser Arg  Thr Glu Ile Ser Ser  Ser Arg Thr 
    4520                 4525                 4530             


Ser Ile  Ser Asp Leu Asp Arg  Pro Thr Ile Ala Pro  Asp Ile Ser 
    4535                 4540                 4545             


Thr Gly  Met Ile Thr Arg Leu  Phe Thr Ser Pro Ile  Met Thr Lys 
    4550                 4555                 4560             


Ser Ala  Glu Met Thr Val Thr  Thr Gln Thr Thr Thr  Pro Gly Ala 
    4565                 4570                 4575             


Thr Ser  Gln Gly Ile Leu Pro  Trp Asp Thr Ser Thr  Thr Leu Phe 
    4580                 4585                 4590             


Gln Gly  Gly Thr His Ser Thr  Val Ser Gln Gly Phe  Pro His Ser 
    4595                 4600                 4605             


Glu Ile  Thr Thr Leu Arg Ser  Arg Thr Pro Gly Asp  Val Ser Trp 
    4610                 4615                 4620             


Met Thr  Thr Pro Pro Val Glu  Glu Thr Ser Ser Gly  Phe Ser Leu 
    4625                 4630                 4635             


Met Ser  Pro Ser Met Thr Ser  Pro Ser Pro Val Ser  Ser Thr Ser 
    4640                 4645                 4650             


Pro Glu  Ser Ile Pro Ser Ser  Pro Leu Pro Val Thr  Ala Leu Leu 
    4655                 4660                 4665             


Thr Ser  Val Leu Val Thr Thr  Thr Asn Val Leu Gly  Thr Thr Ser 
    4670                 4675                 4680             


Pro Glu  Pro Val Thr Ser Ser  Pro Pro Asn Leu Ser  Ser Pro Thr 
    4685                 4690                 4695             


Gln Glu  Arg Leu Thr Thr Tyr  Lys Asp Thr Ala His  Thr Glu Ala 
    4700                 4705                 4710             


Met His  Ala Ser Met His Thr  Asn Thr Ala Val Ala  Asn Val Gly 
    4715                 4720                 4725             


Thr Ser  Ile Ser Gly His Glu  Ser Gln Ser Ser Val  Pro Ala Asp 
    4730                 4735                 4740             


Ser His  Thr Ser Lys Ala Thr  Ser Pro Met Gly Ile  Thr Phe Ala 
    4745                 4750                 4755             


Met Gly  Asp Thr Ser Val Ser  Thr Ser Thr Pro Ala  Phe Phe Glu 
    4760                 4765                 4770             


Thr Arg  Ile Gln Thr Glu Ser  Thr Ser Ser Leu Ile  Pro Gly Leu 
    4775                 4780                 4785             


Arg Asp  Thr Arg Thr Ser Glu  Glu Ile Asn Thr Val  Thr Glu Thr 
    4790                 4795                 4800             


Ser Thr  Val Leu Ser Glu Val  Pro Thr Thr Thr Thr  Thr Glu Val 
    4805                 4810                 4815             


Ser Arg  Thr Glu Val Ile Thr  Ser Ser Arg Thr Thr  Ile Ser Gly 
    4820                 4825                 4830             


Pro Asp  His Ser Lys Met Ser  Pro Tyr Ile Ser Thr  Glu Thr Ile 
    4835                 4840                 4845             


Thr Arg  Leu Ser Thr Phe Pro  Phe Val Thr Gly Ser  Thr Glu Met 
    4850                 4855                 4860             


Ala Ile  Thr Asn Gln Thr Gly  Pro Ile Gly Thr Ile  Ser Gln Ala 
    4865                 4870                 4875             


Thr Leu  Thr Leu Asp Thr Ser  Ser Thr Ala Ser Trp  Glu Gly Thr 
    4880                 4885                 4890             


His Ser  Pro Val Thr Gln Arg  Phe Pro His Ser Glu  Glu Thr Thr 
    4895                 4900                 4905             


Thr Met  Ser Arg Ser Thr Lys  Gly Val Ser Trp Gln  Ser Pro Pro 
    4910                 4915                 4920             


Ser Val  Glu Glu Thr Ser Ser  Pro Ser Ser Pro Val  Pro Leu Pro 
    4925                 4930                 4935             


Ala Ile  Thr Ser His Ser Ser  Leu Tyr Ser Ala Val  Ser Gly Ser 
    4940                 4945                 4950             


Ser Pro  Thr Ser Ala Leu Pro  Val Thr Ser Leu Leu  Thr Ser Gly 
    4955                 4960                 4965             


Arg Arg  Lys Thr Ile Asp Met  Leu Asp Thr His Ser  Glu Leu Val 
    4970                 4975                 4980             


Thr Ser  Ser Leu Pro Ser Ala  Ser Ser Phe Ser Gly  Glu Ile Leu 
    4985                 4990                 4995             


Thr Ser  Glu Ala Ser Thr Asn  Thr Glu Thr Ile His  Phe Ser Glu 
    5000                 5005                 5010             


Asn Thr  Ala Glu Thr Asn Met  Gly Thr Thr Asn Ser  Met His Lys 
    5015                 5020                 5025             


Leu His  Ser Ser Val Ser Ile  His Ser Gln Pro Ser  Gly His Thr 
    5030                 5035                 5040             


Pro Pro  Lys Val Thr Gly Ser  Met Met Glu Asp Ala  Ile Val Ser 
    5045                 5050                 5055             


Thr Ser  Thr Pro Gly Ser Pro  Glu Thr Lys Asn Val  Asp Arg Asp 
    5060                 5065                 5070             


Ser Thr  Ser Pro Leu Thr Pro  Glu Leu Lys Glu Asp  Ser Thr Ala 
    5075                 5080                 5085             


Leu Val  Met Asn Ser Thr Thr  Glu Ser Asn Thr Val  Phe Ser Ser 
    5090                 5095                 5100             


Val Ser  Leu Asp Ala Ala Thr  Glu Val Ser Arg Ala  Glu Val Thr 
    5105                 5110                 5115             


Tyr Tyr  Asp Pro Thr Phe Met  Pro Ala Ser Ala Gln  Ser Thr Lys 
    5120                 5125                 5130             


Ser Pro  Asp Ile Ser Pro Glu  Ala Ser Ser Ser His  Ser Asn Ser 
    5135                 5140                 5145             


Pro Pro  Leu Thr Ile Ser Thr  His Lys Thr Ile Ala  Thr Gln Thr 
    5150                 5155                 5160             


Gly Pro  Ser Gly Val Thr Ser  Leu Gly Gln Leu Thr  Leu Asp Thr 
    5165                 5170                 5175             


Ser Thr  Ile Ala Thr Ser Ala  Gly Thr Pro Ser Ala  Arg Thr Gln 
    5180                 5185                 5190             


Asp Phe  Val Asp Ser Glu Thr  Thr Ser Val Met Asn  Asn Asp Leu 
    5195                 5200                 5205             


Asn Asp  Val Leu Lys Thr Ser  Pro Phe Ser Ala Glu  Glu Ala Asn 
    5210                 5215                 5220             


Ser Leu  Ser Ser Gln Ala Pro  Leu Leu Val Thr Thr  Ser Pro Ser 
    5225                 5230                 5235             


Pro Val  Thr Ser Thr Leu Gln  Glu His Ser Thr Ser  Ser Leu Val 
    5240                 5245                 5250             


Ser Val  Thr Ser Val Pro Thr  Pro Thr Leu Ala Lys  Ile Thr Asp 
    5255                 5260                 5265             


Met Asp  Thr Asn Leu Glu Pro  Val Thr Arg Ser Pro  Gln Asn Leu 
    5270                 5275                 5280             


Arg Asn  Thr Leu Ala Thr Ser  Glu Ala Thr Thr Asp  Thr His Thr 
    5285                 5290                 5295             


Met His  Pro Ser Ile Asn Thr  Ala Val Ala Asn Val  Gly Thr Thr 
    5300                 5305                 5310             


Ser Ser  Pro Asn Glu Phe Tyr  Phe Thr Val Ser Pro  Asp Ser Asp 
    5315                 5320                 5325             


Pro Tyr  Lys Ala Thr Ser Ala  Val Val Ile Thr Ser  Thr Ser Gly 
    5330                 5335                 5340             


Asp Ser  Ile Val Ser Thr Ser  Met Pro Arg Ser Ser  Ala Met Lys 
    5345                 5350                 5355             


Lys Ile  Glu Ser Glu Thr Thr  Phe Ser Leu Ile Phe  Arg Leu Arg 
    5360                 5365                 5370             


Glu Thr  Ser Thr Ser Gln Lys  Ile Gly Ser Ser Ser  Asp Thr Ser 
    5375                 5380                 5385             


Thr Val  Phe Asp Lys Ala Phe  Thr Ala Ala Thr Thr  Glu Val Ser 
    5390                 5395                 5400             


Arg Thr  Glu Leu Thr Ser Ser  Ser Arg Thr Ser Ile  Gln Gly Thr 
    5405                 5410                 5415             


Glu Lys  Pro Thr Met Ser Pro  Asp Thr Ser Thr Arg  Ser Val Thr 
    5420                 5425                 5430             


Met Leu  Ser Thr Phe Ala Gly  Leu Thr Lys Ser Glu  Glu Arg Thr 
    5435                 5440                 5445             


Ile Ala  Thr Gln Thr Gly Pro  His Arg Ala Thr Ser  Gln Gly Thr 
    5450                 5455                 5460             


Leu Thr  Trp Asp Thr Ser Ile  Thr Thr Ser Gln Ala  Gly Thr His 
    5465                 5470                 5475             


Ser Ala  Met Thr His Gly Phe  Ser Gln Leu Asp Leu  Ser Thr Leu 
    5480                 5485                 5490             


Thr Ser  Arg Val Pro Glu Tyr  Ile Ser Gly Thr Ser  Pro Pro Ser 
    5495                 5500                 5505             


Val Glu  Lys Thr Ser Ser Ser  Ser Ser Leu Leu Ser  Leu Pro Ala 
    5510                 5515                 5520             


Ile Thr  Ser Pro Ser Pro Val  Pro Thr Thr Leu Pro  Glu Ser Arg 
    5525                 5530                 5535             


Pro Ser  Ser Pro Val His Leu  Thr Ser Leu Pro Thr  Ser Gly Leu 
    5540                 5545                 5550             


Val Lys  Thr Thr Asp Met Leu  Ala Ser Val Ala Ser  Leu Pro Pro 
    5555                 5560                 5565             


Asn Leu  Gly Ser Thr Ser His  Lys Ile Pro Thr Thr  Ser Glu Asp 
    5570                 5575                 5580             


Ile Lys  Asp Thr Glu Lys Met  Tyr Pro Ser Thr Asn  Ile Ala Val 
    5585                 5590                 5595             


Thr Asn  Val Gly Thr Thr Thr  Ser Glu Lys Glu Ser  Tyr Ser Ser 
    5600                 5605                 5610             


Val Pro  Ala Tyr Ser Glu Pro  Pro Lys Val Thr Ser  Pro Met Val 
    5615                 5620                 5625             


Thr Ser  Phe Asn Ile Arg Asp  Thr Ile Val Ser Thr  Ser Met Pro 
    5630                 5635                 5640             


Gly Ser  Ser Glu Ile Thr Arg  Ile Glu Met Glu Ser  Thr Phe Ser 
    5645                 5650                 5655             


Leu Ala  His Gly Leu Lys Gly  Thr Ser Thr Ser Gln  Asp Pro Ile 
    5660                 5665                 5670             


Val Ser  Thr Glu Lys Ser Ala  Val Leu His Lys Leu  Thr Thr Gly 
    5675                 5680                 5685             


Ala Thr  Glu Thr Ser Arg Thr  Glu Val Ala Ser Ser  Arg Arg Thr 
    5690                 5695                 5700             


Ser Ile  Pro Gly Pro Asp His  Ser Thr Glu Ser Pro  Asp Ile Ser 
    5705                 5710                 5715             


Thr Glu  Val Ile Pro Ser Leu  Pro Ile Ser Leu Gly  Ile Thr Glu 
    5720                 5725                 5730             


Ser Ser  Asn Met Thr Ile Ile  Thr Arg Thr Gly Pro  Pro Leu Gly 
    5735                 5740                 5745             


Ser Thr  Ser Gln Gly Thr Phe  Thr Leu Asp Thr Pro  Thr Thr Ser 
    5750                 5755                 5760             


Ser Arg  Ala Gly Thr His Ser  Met Ala Thr Gln Glu  Phe Pro His 
    5765                 5770                 5775             


Ser Glu  Met Thr Thr Val Met  Asn Lys Asp Pro Glu  Ile Leu Ser 
    5780                 5785                 5790             


Trp Thr  Ile Pro Pro Ser Ile  Glu Lys Thr Ser Phe  Ser Ser Ser 
    5795                 5800                 5805             


Leu Met  Pro Ser Pro Ala Met  Thr Ser Pro Pro Val  Ser Ser Thr 
    5810                 5815                 5820             


Leu Pro  Lys Thr Ile His Thr  Thr Pro Ser Pro Met  Thr Ser Leu 
    5825                 5830                 5835             


Leu Thr  Pro Ser Leu Val Met  Thr Thr Asp Thr Leu  Gly Thr Ser 
    5840                 5845                 5850             


Pro Glu  Pro Thr Thr Ser Ser  Pro Pro Asn Leu Ser  Ser Thr Ser 
    5855                 5860                 5865             


His Glu  Ile Leu Thr Thr Asp  Glu Asp Thr Thr Ala  Ile Glu Ala 
    5870                 5875                 5880             


Met His  Pro Ser Thr Ser Thr  Ala Ala Thr Asn Val  Glu Thr Thr 
    5885                 5890                 5895             


Ser Ser  Gly His Gly Ser Gln  Ser Ser Val Leu Ala  Asp Ser Glu 
    5900                 5905                 5910             


Lys Thr  Lys Ala Thr Ala Pro  Met Asp Thr Thr Ser  Thr Met Gly 
    5915                 5920                 5925             


His Thr  Thr Val Ser Thr Ser  Met Ser Val Ser Ser  Glu Thr Thr 
    5930                 5935                 5940             


Lys Ile  Lys Arg Glu Ser Thr  Tyr Ser Leu Thr Pro  Gly Leu Arg 
    5945                 5950                 5955             


Glu Thr  Ser Ile Ser Gln Asn  Ala Ser Phe Ser Thr  Asp Thr Ser 
    5960                 5965                 5970             


Ile Val  Leu Ser Glu Val Pro  Thr Gly Thr Thr Ala  Glu Val Ser 
    5975                 5980                 5985             


Arg Thr  Glu Val Thr Ser Ser  Gly Arg Thr Ser Ile  Pro Gly Pro 
    5990                 5995                 6000             


Ser Gln  Ser Thr Val Leu Pro  Glu Ile Ser Thr Arg  Thr Met Thr 
    6005                 6010                 6015             


Arg Leu  Phe Ala Ser Pro Thr  Met Thr Glu Ser Ala  Glu Met Thr 
    6020                 6025                 6030             


Ile Pro  Thr Gln Thr Gly Pro  Ser Gly Ser Thr Ser  Gln Asp Thr 
    6035                 6040                 6045             


Leu Thr  Leu Asp Thr Ser Thr  Thr Lys Ser Gln Ala  Lys Thr His 
    6050                 6055                 6060             


Ser Thr  Leu Thr Gln Arg Phe  Pro His Ser Glu Met  Thr Thr Leu 
    6065                 6070                 6075             


Met Ser  Arg Gly Pro Gly Asp  Met Ser Trp Gln Ser  Ser Pro Ser 
    6080                 6085                 6090             


Leu Glu  Asn Pro Ser Ser Leu  Pro Ser Leu Leu Ser  Leu Pro Ala 
    6095                 6100                 6105             


Thr Thr  Ser Pro Pro Pro Ile  Ser Ser Thr Leu Pro  Val Thr Ile 
    6110                 6115                 6120             


Ser Ser  Ser Pro Leu Pro Val  Thr Ser Leu Leu Thr  Ser Ser Pro 
    6125                 6130                 6135             


Val Thr  Thr Thr Asp Met Leu  His Thr Ser Pro Glu  Leu Val Thr 
    6140                 6145                 6150             


Ser Ser  Pro Pro Lys Leu Ser  His Thr Ser Asp Glu  Arg Leu Thr 
    6155                 6160                 6165             


Thr Gly  Lys Asp Thr Thr Asn  Thr Glu Ala Val His  Pro Ser Thr 
    6170                 6175                 6180             


Asn Thr  Ala Ala Ser Asn Val  Glu Ile Pro Ser Ser  Gly His Glu 
    6185                 6190                 6195             


Ser Pro  Ser Ser Ala Leu Ala  Asp Ser Glu Thr Ser  Lys Ala Thr 
    6200                 6205                 6210             


Ser Pro  Met Phe Ile Thr Ser  Thr Gln Glu Asp Thr  Thr Val Ala 
    6215                 6220                 6225             


Ile Ser  Thr Pro His Phe Leu  Glu Thr Ser Arg Ile  Gln Lys Glu 
    6230                 6235                 6240             


Ser Ile  Ser Ser Leu Ser Pro  Lys Leu Arg Glu Thr  Gly Ser Ser 
    6245                 6250                 6255             


Val Glu  Thr Ser Ser Ala Ile  Glu Thr Ser Ala Val  Leu Ser Glu 
    6260                 6265                 6270             


Val Ser  Ile Gly Ala Thr Thr  Glu Ile Ser Arg Thr  Glu Val Thr 
    6275                 6280                 6285             


Ser Ser  Ser Arg Thr Ser Ile  Ser Gly Ser Ala Glu  Ser Thr Met 
    6290                 6295                 6300             


Leu Pro  Glu Ile Ser Thr Thr  Arg Lys Ile Ile Lys  Phe Pro Thr 
    6305                 6310                 6315             


Ser Pro  Ile Leu Ala Glu Ser  Ser Glu Met Thr Ile  Lys Thr Gln 
    6320                 6325                 6330             


Thr Ser  Pro Pro Gly Ser Thr  Ser Glu Ser Thr Phe  Thr Leu Asp 
    6335                 6340                 6345             


Thr Ser  Thr Thr Pro Ser Leu  Val Ile Thr His Ser  Thr Met Thr 
    6350                 6355                 6360             


Gln Arg  Leu Pro His Ser Glu  Ile Thr Thr Leu Val  Ser Arg Gly 
    6365                 6370                 6375             


Ala Gly  Asp Val Pro Arg Pro  Ser Ser Leu Pro Val  Glu Glu Thr 
    6380                 6385                 6390             


Ser Pro  Pro Ser Ser Gln Leu  Ser Leu Ser Ala Met  Ile Ser Pro 
    6395                 6400                 6405             


Ser Pro  Val Ser Ser Thr Leu  Pro Ala Ser Ser His  Ser Ser Ser 
    6410                 6415                 6420             


Ala Ser  Val Thr Ser Leu Leu  Thr Pro Gly Gln Val  Lys Thr Thr 
    6425                 6430                 6435             


Glu Val  Leu Asp Ala Ser Ala  Glu Pro Glu Thr Ser  Ser Pro Pro 
    6440                 6445                 6450             


Ser Leu  Ser Ser Thr Ser Val  Glu Ile Leu Ala Thr  Ser Glu Val 
    6455                 6460                 6465             


Thr Thr  Asp Thr Glu Lys Ile  His Pro Phe Ser Asn  Thr Ala Val 
    6470                 6475                 6480             


Thr Lys  Val Gly Thr Ser Ser  Ser Gly His Glu Ser  Pro Ser Ser 
    6485                 6490                 6495             


Val Leu  Pro Asp Ser Glu Thr  Thr Lys Ala Thr Ser  Ala Met Gly 
    6500                 6505                 6510             


Thr Ile  Ser Ile Met Gly Asp  Thr Ser Val Ser Thr  Leu Thr Pro 
    6515                 6520                 6525             


Ala Leu  Ser Asn Thr Arg Lys  Ile Gln Ser Glu Pro  Ala Ser Ser 
    6530                 6535                 6540             


Leu Thr  Thr Arg Leu Arg Glu  Thr Ser Thr Ser Glu  Glu Thr Ser 
    6545                 6550                 6555             


Leu Ala  Thr Glu Ala Asn Thr  Val Leu Ser Lys Val  Ser Thr Gly 
    6560                 6565                 6570             


Ala Thr  Thr Glu Val Ser Arg  Thr Glu Ala Ile Ser  Phe Ser Arg 
    6575                 6580                 6585             


Thr Ser  Met Ser Gly Pro Glu  Gln Ser Thr Met Ser  Gln Asp Ile 
    6590                 6595                 6600             


Ser Ile  Gly Thr Ile Pro Arg  Ile Ser Ala Ser Ser  Val Leu Thr 
    6605                 6610                 6615             


Glu Ser  Ala Lys Met Thr Ile  Thr Thr Gln Thr Gly  Pro Ser Glu 
    6620                 6625                 6630             


Ser Thr  Leu Glu Ser Thr Leu  Asn Leu Asn Thr Ala  Thr Thr Pro 
    6635                 6640                 6645             


Ser Trp  Val Glu Thr His Ser  Ile Val Ile Gln Gly  Phe Pro His 
    6650                 6655                 6660             


Pro Glu  Met Thr Thr Ser Met  Gly Arg Gly Pro Gly  Gly Val Ser 
    6665                 6670                 6675             


Trp Pro  Ser Pro Pro Phe Val  Lys Glu Thr Ser Pro  Pro Ser Ser 
    6680                 6685                 6690             


Pro Leu  Ser Leu Pro Ala Val  Thr Ser Pro His Pro  Val Ser Thr 
    6695                 6700                 6705             


Thr Phe  Leu Ala His Ile Pro  Pro Ser Pro Leu Pro  Val Thr Ser 
    6710                 6715                 6720             


Leu Leu  Thr Ser Gly Pro Ala  Thr Thr Thr Asp Ile  Leu Gly Thr 
    6725                 6730                 6735             


Ser Thr  Glu Pro Gly Thr Ser  Ser Ser Ser Ser Leu  Ser Thr Thr 
    6740                 6745                 6750             


Ser His  Glu Arg Leu Thr Thr  Tyr Lys Asp Thr Ala  His Thr Glu 
    6755                 6760                 6765             


Ala Val  His Pro Ser Thr Asn  Thr Gly Gly Thr Asn  Val Ala Thr 
    6770                 6775                 6780             


Thr Ser  Ser Gly Tyr Lys Ser  Gln Ser Ser Val Leu  Ala Asp Ser 
    6785                 6790                 6795             


Ser Pro  Met Cys Thr Thr Ser  Thr Met Gly Asp Thr  Ser Val Leu 
    6800                 6805                 6810             


Thr Ser  Thr Pro Ala Phe Leu  Glu Thr Arg Arg Ile  Gln Thr Glu 
    6815                 6820                 6825             


Leu Ala  Ser Ser Leu Thr Pro  Gly Leu Arg Glu Ser  Ser Gly Ser 
    6830                 6835                 6840             


Glu Gly  Thr Ser Ser Gly Thr  Lys Met Ser Thr Val  Leu Ser Lys 
    6845                 6850                 6855             


Val Pro  Thr Gly Ala Thr Thr  Glu Ile Ser Lys Glu  Asp Val Thr 
    6860                 6865                 6870             


Ser Ile  Pro Gly Pro Ala Gln  Ser Thr Ile Ser Pro  Asp Ile Ser 
    6875                 6880                 6885             


Thr Arg  Thr Val Ser Trp Phe  Ser Thr Ser Pro Val  Met Thr Glu 
    6890                 6895                 6900             


Ser Ala  Glu Ile Thr Met Asn  Thr His Thr Ser Pro  Leu Gly Ala 
    6905                 6910                 6915             


Thr Thr  Gln Gly Thr Ser Thr  Leu Asp Thr Ser Ser  Thr Thr Ser 
    6920                 6925                 6930             


Leu Thr  Met Thr His Ser Thr  Ile Ser Gln Gly Phe  Ser His Ser 
    6935                 6940                 6945             


Gln Met  Ser Thr Leu Met Arg  Arg Gly Pro Glu Asp  Val Ser Trp 
    6950                 6955                 6960             


Met Ser  Pro Pro Leu Leu Glu  Lys Thr Arg Pro Ser  Phe Ser Leu 
    6965                 6970                 6975             


Met Ser  Ser Pro Ala Thr Thr  Ser Pro Ser Pro Val  Ser Ser Thr 
    6980                 6985                 6990             


Leu Pro  Glu Ser Ile Ser Ser  Ser Pro Leu Pro Val  Thr Ser Leu 
    6995                 7000                 7005             


Leu Thr  Ser Gly Leu Ala Lys  Thr Thr Asp Met Leu  His Lys Ser 
    7010                 7015                 7020             


Ser Glu  Pro Val Thr Asn Ser  Pro Ala Asn Leu Ser  Ser Thr Ser 
    7025                 7030                 7035             


Val Glu  Ile Leu Ala Thr Ser  Glu Val Thr Thr Asp  Thr Glu Lys 
    7040                 7045                 7050             


Thr His  Pro Ser Ser Asn Arg  Thr Val Thr Asp Val  Gly Thr Ser 
    7055                 7060                 7065             


Ser Ser  Gly His Glu Ser Thr  Ser Phe Val Leu Ala  Asp Ser Gln 
    7070                 7075                 7080             


Thr Ser  Lys Val Thr Ser Pro  Met Val Ile Thr Ser  Thr Met Glu 
    7085                 7090                 7095             


Asp Thr  Ser Val Ser Thr Ser  Thr Pro Gly Phe Phe  Glu Thr Ser 
    7100                 7105                 7110             


Arg Ile  Gln Thr Glu Pro Thr  Ser Ser Leu Thr Leu  Gly Leu Arg 
    7115                 7120                 7125             


Lys Thr  Ser Ser Ser Glu Gly  Thr Ser Leu Ala Thr  Glu Met Ser 
    7130                 7135                 7140             


Thr Val  Leu Ser Gly Val Pro  Thr Gly Ala Thr Ala  Glu Val Ser 
    7145                 7150                 7155             


Arg Thr  Glu Val Thr Ser Ser  Ser Arg Thr Ser Ile  Ser Gly Phe 
    7160                 7165                 7170             


Ala Gln  Leu Thr Val Ser Pro  Glu Thr Ser Thr Glu  Thr Ile Thr 
    7175                 7180                 7185             


Arg Leu  Pro Thr Ser Ser Ile  Met Thr Glu Ser Ala  Glu Met Met 
    7190                 7195                 7200             


Ile Lys  Thr Gln Thr Asp Pro  Pro Gly Ser Thr Pro  Glu Ser Thr 
    7205                 7210                 7215             


His Thr  Val Asp Ile Ser Thr  Thr Pro Asn Trp Val  Glu Thr His 
    7220                 7225                 7230             


Ser Thr  Val Thr Gln Arg Phe  Ser His Ser Glu Met  Thr Thr Leu 
    7235                 7240                 7245             


Val Ser  Arg Ser Pro Gly Asp  Met Leu Trp Pro Ser  Gln Ser Ser 
    7250                 7255                 7260             


Val Glu  Glu Thr Ser Ser Ala  Ser Ser Leu Leu Ser  Leu Pro Ala 
    7265                 7270                 7275             


Thr Thr  Ser Pro Ser Pro Val  Ser Ser Thr Leu Val  Glu Asp Phe 
    7280                 7285                 7290             


Pro Ser  Ala Ser Leu Pro Val  Thr Ser Leu Leu Asn  Pro Gly Leu 
    7295                 7300                 7305             


Val Ile  Thr Thr Asp Arg Met  Gly Ile Ser Arg Glu  Pro Gly Thr 
    7310                 7315                 7320             


Ser Ser  Thr Ser Asn Leu Ser  Ser Thr Ser His Glu  Arg Leu Thr 
    7325                 7330                 7335             


Thr Leu  Glu Asp Thr Val Asp  Thr Glu Asp Met Gln  Pro Ser Thr 
    7340                 7345                 7350             


His Thr  Ala Val Thr Asn Val  Arg Thr Ser Ile Ser  Gly His Glu 
    7355                 7360                 7365             


Ser Gln  Ser Ser Val Leu Ser  Asp Ser Glu Thr Pro  Lys Ala Thr 
    7370                 7375                 7380             


Ser Pro  Met Gly Thr Thr Tyr  Thr Met Gly Glu Thr  Ser Val Ser 
    7385                 7390                 7395             


Ile Ser  Thr Ser Asp Phe Phe  Glu Thr Ser Arg Ile  Gln Ile Glu 
    7400                 7405                 7410             


Pro Thr  Ser Ser Leu Thr Ser  Gly Leu Arg Glu Thr  Ser Ser Ser 
    7415                 7420                 7425             


Glu Arg  Ile Ser Ser Ala Thr  Glu Gly Ser Thr Val  Leu Ser Glu 
    7430                 7435                 7440             


Val Pro  Ser Gly Ala Thr Thr  Glu Val Ser Arg Thr  Glu Val Ile 
    7445                 7450                 7455             


Ser Ser  Arg Gly Thr Ser Met  Ser Gly Pro Asp Gln  Phe Thr Ile 
    7460                 7465                 7470             


Ser Pro  Asp Ile Ser Thr Glu  Ala Ile Thr Arg Leu  Ser Thr Ser 
    7475                 7480                 7485             


Pro Ile  Met Thr Glu Ser Ala  Glu Ser Ala Ile Thr  Ile Glu Thr 
    7490                 7495                 7500             


Gly Ser  Pro Gly Ala Thr Ser  Glu Gly Thr Leu Thr  Leu Asp Thr 
    7505                 7510                 7515             


Ser Thr  Thr Thr Phe Trp Ser  Gly Thr His Ser Thr  Ala Ser Pro 
    7520                 7525                 7530             


Gly Phe  Ser His Ser Glu Met  Thr Thr Leu Met Ser  Arg Thr Pro 
    7535                 7540                 7545             


Gly Asp  Val Pro Trp Pro Ser  Leu Pro Ser Val Glu  Glu Ala Ser 
    7550                 7555                 7560             


Ser Val  Ser Ser Ser Leu Ser  Ser Pro Ala Met Thr  Ser Thr Ser 
    7565                 7570                 7575             


Phe Phe  Ser Thr Leu Pro Glu  Ser Ile Ser Ser Ser  Pro His Pro 
    7580                 7585                 7590             


Val Thr  Ala Leu Leu Thr Leu  Gly Pro Val Lys Thr  Thr Asp Met 
    7595                 7600                 7605             


Leu Arg  Thr Ser Ser Glu Pro  Glu Thr Ser Ser Pro  Pro Asn Leu 
    7610                 7615                 7620             


Ser Ser  Thr Ser Ala Glu Ile  Leu Ala Thr Ser Glu  Val Thr Lys 
    7625                 7630                 7635             


Asp Arg  Glu Lys Ile His Pro  Ser Ser Asn Thr Pro  Val Val Asn 
    7640                 7645                 7650             


Val Gly  Thr Val Ile Tyr Lys  His Leu Ser Pro Ser  Ser Val Leu 
    7655                 7660                 7665             


Ala Asp  Leu Val Thr Thr Lys  Pro Thr Ser Pro Met  Ala Thr Thr 
    7670                 7675                 7680             


Ser Thr  Leu Gly Asn Thr Ser  Val Ser Thr Ser Thr  Pro Ala Phe 
    7685                 7690                 7695             


Pro Glu  Thr Met Met Thr Gln  Pro Thr Ser Ser Leu  Thr Ser Gly 
    7700                 7705                 7710             


Leu Arg  Glu Ile Ser Thr Ser  Gln Glu Thr Ser Ser  Ala Thr Glu 
    7715                 7720                 7725             


Arg Ser  Ala Ser Leu Ser Gly  Met Pro Thr Gly Ala  Thr Thr Lys 
    7730                 7735                 7740             


Val Ser  Arg Thr Glu Ala Leu  Ser Leu Gly Arg Thr  Ser Thr Pro 
    7745                 7750                 7755             


Gly Pro  Ala Gln Ser Thr Ile  Ser Pro Glu Ile Ser  Thr Glu Thr 
    7760                 7765                 7770             


Ile Thr  Arg Ile Ser Thr Pro  Leu Thr Thr Thr Gly  Ser Ala Glu 
    7775                 7780                 7785             


Met Thr  Ile Thr Pro Lys Thr  Gly His Ser Gly Ala  Ser Ser Gln 
    7790                 7795                 7800             


Gly Thr  Phe Thr Leu Asp Thr  Ser Ser Arg Ala Ser  Trp Pro Gly 
    7805                 7810                 7815             


Thr His  Ser Ala Ala Thr His  Arg Ser Pro His Ser  Gly Met Thr 
    7820                 7825                 7830             


Thr Pro  Met Ser Arg Gly Pro  Glu Asp Val Ser Trp  Pro Ser Arg 
    7835                 7840                 7845             


Pro Ser  Val Glu Lys Thr Ser  Pro Pro Ser Ser Leu  Val Ser Leu 
    7850                 7855                 7860             


Ser Ala  Val Thr Ser Pro Ser  Pro Leu Tyr Ser Thr  Pro Ser Glu 
    7865                 7870                 7875             


Ser Ser  His Ser Ser Pro Leu  Arg Val Thr Ser Leu  Phe Thr Pro 
    7880                 7885                 7890             


Val Met  Met Lys Thr Thr Asp  Met Leu Asp Thr Ser  Leu Glu Pro 
    7895                 7900                 7905             


Val Thr  Thr Ser Pro Pro Ser  Met Asn Ile Thr Ser  Asp Glu Ser 
    7910                 7915                 7920             


Leu Ala  Thr Ser Lys Ala Thr  Met Glu Thr Glu Ala  Ile Gln Leu 
    7925                 7930                 7935             


Ser Glu  Asn Thr Ala Val Thr  Gln Met Gly Thr Ile  Ser Ala Arg 
    7940                 7945                 7950             


Gln Glu  Phe Tyr Ser Ser Tyr  Pro Gly Leu Pro Glu  Pro Ser Lys 
    7955                 7960                 7965             


Val Thr  Ser Pro Val Val Thr  Ser Ser Thr Ile Lys  Asp Ile Val 
    7970                 7975                 7980             


Ser Thr  Thr Ile Pro Ala Ser  Ser Glu Ile Thr Arg  Ile Glu Met 
    7985                 7990                 7995             


Glu Ser  Thr Ser Thr Leu Thr  Pro Thr Pro Arg Glu  Thr Ser Thr 
    8000                 8005                 8010             


Ser Gln  Glu Ile His Ser Ala  Thr Lys Pro Ser Thr  Val Pro Tyr 
    8015                 8020                 8025             


Lys Ala  Leu Thr Ser Ala Thr  Ile Glu Asp Ser Met  Thr Gln Val 
    8030                 8035                 8040             


Met Ser  Ser Ser Arg Gly Pro  Ser Pro Asp Gln Ser  Thr Met Ser 
    8045                 8050                 8055             


Gln Asp  Ile Ser Thr Glu Val  Ile Thr Arg Leu Ser  Thr Ser Pro 
    8060                 8065                 8070             


Ile Lys  Thr Glu Ser Thr Glu  Met Thr Ile Thr Thr  Gln Thr Gly 
    8075                 8080                 8085             


Ser Pro  Gly Ala Thr Ser Arg  Gly Thr Leu Thr Leu  Asp Thr Ser 
    8090                 8095                 8100             


Thr Thr  Phe Met Ser Gly Thr  His Ser Thr Ala Ser  Gln Gly Phe 
    8105                 8110                 8115             


Ser His  Ser Gln Met Thr Ala  Leu Met Ser Arg Thr  Pro Gly Asp 
    8120                 8125                 8130             


Val Pro  Trp Leu Ser His Pro  Ser Val Glu Glu Ala  Ser Ser Ala 
    8135                 8140                 8145             


Ser Phe  Ser Leu Ser Ser Pro  Val Met Thr Ser Ser  Ser Pro Val 
    8150                 8155                 8160             


Ser Ser  Thr Leu Pro Asp Ser  Ile His Ser Ser Ser  Leu Pro Val 
    8165                 8170                 8175             


Thr Ser  Leu Leu Thr Ser Gly  Leu Val Lys Thr Thr  Glu Leu Leu 
    8180                 8185                 8190             


Gly Thr  Ser Ser Glu Pro Glu  Thr Ser Ser Pro Pro  Asn Leu Ser 
    8195                 8200                 8205             


Ser Thr  Ser Ala Glu Ile Leu  Ala Ile Thr Glu Val  Thr Thr Asp 
    8210                 8215                 8220             


Thr Glu  Lys Leu Glu Met Thr  Asn Val Val Thr Ser  Gly Tyr Thr 
    8225                 8230                 8235             


His Glu  Ser Pro Ser Ser Val  Leu Ala Asp Ser Val  Thr Thr Lys 
    8240                 8245                 8250             


Ala Thr  Ser Ser Met Gly Ile  Thr Tyr Pro Thr Gly  Asp Thr Asn 
    8255                 8260                 8265             


Val Leu  Thr Ser Thr Pro Ala  Phe Ser Asp Thr Ser  Arg Ile Gln 
    8270                 8275                 8280             


Thr Lys  Ser Lys Leu Ser Leu  Thr Pro Gly Leu Met  Glu Thr Ser 
    8285                 8290                 8295             


Ile Ser  Glu Glu Thr Ser Ser  Ala Thr Glu Lys Ser  Thr Val Leu 
    8300                 8305                 8310             


Ser Ser  Val Pro Thr Gly Ala  Thr Thr Glu Val Ser  Arg Thr Glu 
    8315                 8320                 8325             


Ala Ile  Ser Ser Ser Arg Thr  Ser Ile Pro Gly Pro  Ala Gln Ser 
    8330                 8335                 8340             


Thr Met  Ser Ser Asp Thr Ser  Met Glu Thr Ile Thr  Arg Ile Ser 
    8345                 8350                 8355             


Thr Pro  Leu Thr Arg Lys Glu  Ser Thr Asp Met Ala  Ile Thr Pro 
    8360                 8365                 8370             


Lys Thr  Gly Pro Ser Gly Ala  Thr Ser Gln Gly Thr  Phe Thr Leu 
    8375                 8380                 8385             


Asp Ser  Ser Ser Thr Ala Ser  Trp Pro Gly Thr His  Ser Ala Thr 
    8390                 8395                 8400             


Thr Gln  Arg Phe Pro Gln Ser  Val Val Thr Thr Pro  Met Ser Arg 
    8405                 8410                 8415             


Gly Pro  Glu Asp Val Ser Trp  Pro Ser Pro Leu Ser  Val Glu Lys 
    8420                 8425                 8430             


Asn Ser  Pro Pro Ser Ser Leu  Val Ser Ser Ser Ser  Val Thr Ser 
    8435                 8440                 8445             


Pro Ser  Pro Leu Tyr Ser Thr  Pro Ser Gly Ser Ser  His Ser Ser 
    8450                 8455                 8460             


Pro Val  Pro Val Thr Ser Leu  Phe Thr Ser Ile Met  Met Lys Ala 
    8465                 8470                 8475             


Thr Asp  Met Leu Asp Ala Ser  Leu Glu Pro Glu Thr  Thr Ser Ala 
    8480                 8485                 8490             


Pro Asn  Met Asn Ile Thr Ser  Asp Glu Ser Leu Ala  Ala Ser Lys 
    8495                 8500                 8505             


Ala Thr  Thr Glu Thr Glu Ala  Ile His Val Phe Glu  Asn Thr Ala 
    8510                 8515                 8520             


Ala Ser  His Val Glu Thr Thr  Ser Ala Thr Glu Glu  Leu Tyr Ser 
    8525                 8530                 8535             


Ser Ser  Pro Gly Phe Ser Glu  Pro Thr Lys Val Ile  Ser Pro Val 
    8540                 8545                 8550             


Val Thr  Ser Ser Ser Ile Arg  Asp Asn Met Val Ser  Thr Thr Met 
    8555                 8560                 8565             


Pro Gly  Ser Ser Gly Ile Thr  Arg Ile Glu Ile Glu  Ser Met Ser 
    8570                 8575                 8580             


Ser Leu  Thr Pro Gly Leu Arg  Glu Thr Arg Thr Ser  Gln Asp Ile 
    8585                 8590                 8595             


Thr Ser  Ser Thr Glu Thr Ser  Thr Val Leu Tyr Lys  Met Pro Ser 
    8600                 8605                 8610             


Gly Ala  Thr Pro Glu Val Ser  Arg Thr Glu Val Met  Pro Ser Ser 
    8615                 8620                 8625             


Arg Thr  Ser Ile Pro Gly Pro  Ala Gln Ser Thr Met  Ser Leu Asp 
    8630                 8635                 8640             


Ile Ser  Asp Glu Val Val Thr  Arg Leu Ser Thr Ser  Pro Ile Met 
    8645                 8650                 8655             


Thr Glu  Ser Ala Glu Ile Thr  Ile Thr Thr Gln Thr  Gly Tyr Ser 
    8660                 8665                 8670             


Leu Ala  Thr Ser Gln Val Thr  Leu Pro Leu Gly Thr  Ser Met Thr 
    8675                 8680                 8685             


Phe Leu  Ser Gly Thr His Ser  Thr Met Ser Gln Gly  Leu Ser His 
    8690                 8695                 8700             


Ser Glu  Met Thr Asn Leu Met  Ser Arg Gly Pro Glu  Ser Leu Ser 
    8705                 8710                 8715             


Trp Thr  Ser Pro Arg Phe Val  Glu Thr Thr Arg Ser  Ser Ser Ser 
    8720                 8725                 8730             


Leu Thr  Ser Leu Pro Leu Thr  Thr Ser Leu Ser Pro  Val Ser Ser 
    8735                 8740                 8745             


Thr Leu  Leu Asp Ser Ser Pro  Ser Ser Pro Leu Pro  Val Thr Ser 
    8750                 8755                 8760             


Leu Ile  Leu Pro Gly Leu Val  Lys Thr Thr Glu Val  Leu Asp Thr 
    8765                 8770                 8775             


Ser Ser  Glu Pro Lys Thr Ser  Ser Ser Pro Asn Leu  Ser Ser Thr 
    8780                 8785                 8790             


Ser Val  Glu Ile Pro Ala Thr  Ser Glu Ile Met Thr  Asp Thr Glu 
    8795                 8800                 8805             


Lys Ile  His Pro Ser Ser Asn  Thr Ala Val Ala Lys  Val Arg Thr 
    8810                 8815                 8820             


Ser Ser  Ser Val His Glu Ser  His Ser Ser Val Leu  Ala Asp Ser 
    8825                 8830                 8835             


Glu Thr  Thr Ile Thr Ile Pro  Ser Met Gly Ile Thr  Ser Ala Val 
    8840                 8845                 8850             


Asp Asp  Thr Thr Val Phe Thr  Ser Asn Pro Ala Phe  Ser Glu Thr 
    8855                 8860                 8865             


Arg Arg  Ile Pro Thr Glu Pro  Thr Phe Ser Leu Thr  Pro Gly Phe 
    8870                 8875                 8880             


Arg Glu  Thr Ser Thr Ser Glu  Glu Thr Thr Ser Ile  Thr Glu Thr 
    8885                 8890                 8895             


Ser Ala  Val Leu Tyr Gly Val  Pro Thr Ser Ala Thr  Thr Glu Val 
    8900                 8905                 8910             


Ser Met  Thr Glu Ile Met Ser  Ser Asn Arg Ile His  Ile Pro Asp 
    8915                 8920                 8925             


Ser Asp  Gln Ser Thr Met Ser  Pro Asp Ile Ile Thr  Glu Val Ile 
    8930                 8935                 8940             


Thr Arg  Leu Ser Ser Ser Ser  Met Met Ser Glu Ser  Thr Gln Met 
    8945                 8950                 8955             


Thr Ile  Thr Thr Gln Lys Ser  Ser Pro Gly Ala Thr  Ala Gln Ser 
    8960                 8965                 8970             


Thr Leu  Thr Leu Ala Thr Thr  Thr Ala Pro Leu Ala  Arg Thr His 
    8975                 8980                 8985             


Ser Thr  Val Pro Pro Arg Phe  Leu His Ser Glu Met  Thr Thr Leu 
    8990                 8995                 9000             


Met Ser  Arg Ser Pro Glu Asn  Pro Ser Trp Lys Ser  Ser Leu Phe 
    9005                 9010                 9015             


Val Glu  Lys Thr Ser Ser Ser  Ser Ser Leu Leu Ser  Leu Pro Val 
    9020                 9025                 9030             


Thr Thr  Ser Pro Ser Val Ser  Ser Thr Leu Pro Gln  Ser Ile Pro 
    9035                 9040                 9045             


Ser Ser  Ser Phe Ser Val Thr  Ser Leu Leu Thr Pro  Gly Met Val 
    9050                 9055                 9060             


Lys Thr  Thr Asp Thr Ser Thr  Glu Pro Gly Thr Ser  Leu Ser Pro 
    9065                 9070                 9075             


Asn Leu  Ser Gly Thr Ser Val  Glu Ile Leu Ala Ala  Ser Glu Val 
    9080                 9085                 9090             


Thr Thr  Asp Thr Glu Lys Ile  His Pro Ser Ser Ser  Met Ala Val 
    9095                 9100                 9105             


Thr Asn  Val Gly Thr Thr Ser  Ser Gly His Glu Leu  Tyr Ser Ser 
    9110                 9115                 9120             


Val Ser  Ile His Ser Glu Pro  Ser Lys Ala Thr Tyr  Pro Val Gly 
    9125                 9130                 9135             


Thr Pro  Ser Ser Met Ala Glu  Thr Ser Ile Ser Thr  Ser Met Pro 
    9140                 9145                 9150             


Ala Asn  Phe Glu Thr Thr Gly  Phe Glu Ala Glu Pro  Phe Ser His 
    9155                 9160                 9165             


Leu Thr  Ser Gly Phe Arg Lys  Thr Asn Met Ser Leu  Asp Thr Ser 
    9170                 9175                 9180             


Ser Val  Thr Pro Thr Asn Thr  Pro Ser Ser Pro Gly  Ser Thr His 
    9185                 9190                 9195             


Leu Leu  Gln Ser Ser Lys Thr  Asp Phe Thr Ser Ser  Ala Lys Thr 
    9200                 9205                 9210             


Ser Ser  Pro Asp Trp Pro Pro  Ala Ser Gln Tyr Thr  Glu Ile Pro 
    9215                 9220                 9225             


Val Asp  Ile Ile Thr Pro Phe  Asn Ala Ser Pro Ser  Ile Thr Glu 
    9230                 9235                 9240             


Ser Thr  Gly Ile Thr Ser Phe  Pro Glu Ser Arg Phe  Thr Met Ser 
    9245                 9250                 9255             


Val Thr  Glu Ser Thr His His  Leu Ser Thr Asp Leu  Leu Pro Ser 
    9260                 9265                 9270             


Ala Glu  Thr Ile Ser Thr Gly  Thr Val Met Pro Ser  Leu Ser Glu 
    9275                 9280                 9285             


Ala Met  Thr Ser Phe Ala Thr  Thr Gly Val Pro Arg  Ala Ile Ser 
    9290                 9295                 9300             


Gly Ser  Gly Ser Pro Phe Ser  Arg Thr Glu Ser Gly  Pro Gly Asp 
    9305                 9310                 9315             


Ala Thr  Leu Ser Thr Ile Ala  Glu Ser Leu Pro Ser  Ser Thr Pro 
    9320                 9325                 9330             


Val Pro  Phe Ser Ser Ser Thr  Phe Thr Thr Thr Asp  Ser Ser Thr 
    9335                 9340                 9345             


Ile Pro  Ala Leu His Glu Ile  Thr Ser Ser Ser Ala  Thr Pro Tyr 
    9350                 9355                 9360             


Arg Val  Asp Thr Ser Leu Gly  Thr Glu Ser Ser Thr  Thr Glu Gly 
    9365                 9370                 9375             


Arg Leu  Val Met Val Ser Thr  Leu Asp Thr Ser Ser  Gln Pro Gly 
    9380                 9385                 9390             


Arg Thr  Ser Ser Ser Pro Ile  Leu Asp Thr Arg Met  Thr Glu Ser 
    9395                 9400                 9405             


Val Glu  Leu Gly Thr Val Thr  Ser Ala Tyr Gln Val  Pro Ser Leu 
    9410                 9415                 9420             


Ser Thr  Arg Leu Thr Arg Thr  Asp Gly Ile Met Glu  His Ile Thr 
    9425                 9430                 9435             


Lys Ile  Pro Asn Glu Ala Ala  His Arg Gly Thr Ile  Arg Pro Val 
    9440                 9445                 9450             


Lys Gly  Pro Gln Thr Ser Thr  Ser Pro Ala Ser Pro  Lys Gly Leu 
    9455                 9460                 9465             


His Thr  Gly Gly Thr Lys Arg  Met Glu Thr Thr Thr  Thr Ala Leu 
    9470                 9475                 9480             


Lys Thr  Thr Thr Thr Ala Leu  Lys Thr Thr Ser Arg  Ala Thr Leu 
    9485                 9490                 9495             


Thr Thr  Ser Val Tyr Thr Pro  Thr Leu Gly Thr Leu  Thr Pro Leu 
    9500                 9505                 9510             


Asn Ala  Ser Met Gln Met Ala  Ser Thr Ile Pro Thr  Glu Met Met 
    9515                 9520                 9525             


Ile Thr  Thr Pro Tyr Val Phe  Pro Asp Val Pro Glu  Thr Thr Ser 
    9530                 9535                 9540             


Ser Leu  Ala Thr Ser Leu Gly  Ala Glu Thr Ser Thr  Ala Leu Pro 
    9545                 9550                 9555             


Arg Thr  Thr Pro Ser Val Phe  Asn Arg Glu Ser Glu  Thr Thr Ala 
    9560                 9565                 9570             


Ser Leu  Val Ser Arg Ser Gly  Ala Glu Arg Ser Pro  Val Ile Gln 
    9575                 9580                 9585             


Thr Leu  Asp Val Ser Ser Ser  Glu Pro Asp Thr Thr  Ala Ser Trp 
    9590                 9595                 9600             


Val Ile  His Pro Ala Glu Thr  Ile Pro Thr Val Ser  Lys Thr Thr 
    9605                 9610                 9615             


Pro Asn  Phe Phe His Ser Glu  Leu Asp Thr Val Ser  Ser Thr Ala 
    9620                 9625                 9630             


Thr Ser  His Gly Ala Asp Val  Ser Ser Ala Ile Pro  Thr Asn Ile 
    9635                 9640                 9645             


Ser Pro  Ser Glu Leu Asp Ala  Leu Thr Pro Leu Val  Thr Ile Ser 
    9650                 9655                 9660             


Gly Thr  Asp Thr Ser Thr Thr  Phe Pro Thr Leu Thr  Lys Ser Pro 
    9665                 9670                 9675             


His Glu  Thr Glu Thr Arg Thr  Thr Trp Leu Thr His  Pro Ala Glu 
    9680                 9685                 9690             


Thr Ser  Ser Thr Ile Pro Arg  Thr Ile Pro Asn Phe  Ser His His 
    9695                 9700                 9705             


Glu Ser  Asp Ala Thr Pro Ser  Ile Ala Thr Ser Pro  Gly Ala Glu 
    9710                 9715                 9720             


Thr Ser  Ser Ala Ile Pro Ile  Met Thr Val Ser Pro  Gly Ala Glu 
    9725                 9730                 9735             


Asp Leu  Val Thr Ser Gln Val  Thr Ser Ser Gly Thr  Asp Arg Asn 
    9740                 9745                 9750             


Met Thr  Ile Pro Thr Leu Thr  Leu Ser Pro Gly Glu  Pro Lys Thr 
    9755                 9760                 9765             


Ile Ala  Ser Leu Val Thr His  Pro Glu Ala Gln Thr  Ser Ser Ala 
    9770                 9775                 9780             


Ile Pro  Thr Ser Thr Ile Ser  Pro Ala Val Ser Arg  Leu Val Thr 
    9785                 9790                 9795             


Ser Met  Val Thr Ser Leu Ala  Ala Lys Thr Ser Thr  Thr Asn Arg 
    9800                 9805                 9810             


Ala Leu  Thr Asn Ser Pro Gly  Glu Pro Ala Thr Thr  Val Ser Leu 
    9815                 9820                 9825             


Val Thr  His Pro Ala Gln Thr  Ser Pro Thr Val Pro  Trp Thr Thr 
    9830                 9835                 9840             


Ser Ile  Phe Phe His Ser Lys  Ser Asp Thr Thr Pro  Ser Met Thr 
    9845                 9850                 9855             


Thr Ser  His Gly Ala Glu Ser  Ser Ser Ala Val Pro  Thr Pro Thr 
    9860                 9865                 9870             


Val Ser  Thr Glu Val Pro Gly  Val Val Thr Pro Leu  Val Thr Ser 
    9875                 9880                 9885             


Ser Arg  Ala Val Ile Ser Thr  Thr Ile Pro Ile Leu  Thr Leu Ser 
    9890                 9895                 9900             


Pro Gly  Glu Pro Glu Thr Thr  Pro Ser Met Ala Thr  Ser His Gly 
    9905                 9910                 9915             


Glu Glu  Ala Ser Ser Ala Ile  Pro Thr Pro Thr Val  Ser Pro Gly 
    9920                 9925                 9930             


Val Pro  Gly Val Val Thr Ser  Leu Val Thr Ser Ser  Arg Ala Val 
    9935                 9940                 9945             


Thr Ser  Thr Thr Ile Pro Ile  Leu Thr Phe Ser Leu  Gly Glu Pro 
    9950                 9955                 9960             


Glu Thr  Thr Pro Ser Met Ala  Thr Ser His Gly Thr  Glu Ala Gly 
    9965                 9970                 9975             


Ser Ala  Val Pro Thr Val Leu  Pro Glu Val Pro Gly  Met Val Thr 
    9980                 9985                 9990             


Ser Leu  Val Ala Ser Ser Arg   Ala Val Thr Ser Thr   Thr Leu Pro 
    9995                 10000                 10005             


Thr Leu   Thr Leu Ser Pro Gly   Glu Pro Glu Thr Thr   Pro Ser Met 
    10010                 10015                 10020             


Ala Thr   Ser His Gly Ala Glu   Ala Ser Ser Thr Val   Pro Thr Val 
    10025                 10030                 10035             


Ser Pro   Glu Val Pro Gly Val   Val Thr Ser Leu Val   Thr Ser Ser 
    10040                 10045                 10050             


Ser Gly   Val Asn Ser Thr Ser   Ile Pro Thr Leu Ile   Leu Ser Pro 
    10055                 10060                 10065             


Gly Glu   Leu Glu Thr Thr Pro   Ser Met Ala Thr Ser   His Gly Ala 
    10070                 10075                 10080             


Glu Ala   Ser Ser Ala Val Pro   Thr Pro Thr Val Ser   Pro Gly Val 
    10085                 10090                 10095             


Ser Gly   Val Val Thr Pro Leu   Val Thr Ser Ser Arg   Ala Val Thr 
    10100                 10105                 10110             


Ser Thr   Thr Ile Pro Ile Leu   Thr Leu Ser Ser Ser   Glu Pro Glu 
    10115                 10120                 10125             


Thr Thr   Pro Ser Met Ala Thr   Ser His Gly Val Glu   Ala Ser Ser 
    10130                 10135                 10140             


Ala Val   Leu Thr Val Ser Pro   Glu Val Pro Gly Met   Val Thr Ser 
    10145                 10150                 10155             


Leu Val   Thr Ser Ser Arg Ala   Val Thr Ser Thr Thr   Ile Pro Thr 
    10160                 10165                 10170             


Leu Thr   Ile Ser Ser Asp Glu   Pro Glu Thr Thr Thr   Ser Leu Val 
    10175                 10180                 10185             


Thr His   Ser Glu Ala Lys Met   Ile Ser Ala Ile Pro   Thr Leu Ala 
    10190                 10195                 10200             


Val Ser   Pro Thr Val Gln Gly   Leu Val Thr Ser Leu   Val Thr Ser 
    10205                 10210                 10215             


Ser Gly   Ser Glu Thr Ser Ala   Phe Ser Asn Leu Thr   Val Ala Ser 
    10220                 10225                 10230             


Ser Gln   Pro Glu Thr Ile Asp   Ser Trp Val Ala His   Pro Gly Thr 
    10235                 10240                 10245             


Glu Ala   Ser Ser Val Val Pro   Thr Leu Thr Val Ser   Thr Gly Glu 
    10250                 10255                 10260             


Pro Phe   Thr Asn Ile Ser Leu   Val Thr His Pro Ala   Glu Ser Ser 
    10265                 10270                 10275             


Ser Thr   Leu Pro Arg Thr Thr   Ser Arg Phe Ser His   Ser Glu Leu 
    10280                 10285                 10290             


Asp Thr   Met Pro Ser Thr Val   Thr Ser Pro Glu Ala   Glu Ser Ser 
    10295                 10300                 10305             


Ser Ala   Ile Ser Thr Thr Ile   Ser Pro Gly Ile Pro   Gly Val Leu 
    10310                 10315                 10320             


Thr Ser   Leu Val Thr Ser Ser   Gly Arg Asp Ile Ser   Ala Thr Phe 
    10325                 10330                 10335             


Pro Thr   Val Pro Glu Ser Pro   His Glu Ser Glu Ala   Thr Ala Ser 
    10340                 10345                 10350             


Trp Val   Thr His Pro Ala Val   Thr Ser Thr Thr Val   Pro Arg Thr 
    10355                 10360                 10365             


Thr Pro   Asn Tyr Ser His Ser   Glu Pro Asp Thr Thr   Pro Ser Ile 
    10370                 10375                 10380             


Ala Thr   Ser Pro Gly Ala Glu   Ala Thr Ser Asp Phe   Pro Thr Ile 
    10385                 10390                 10395             


Thr Val   Ser Pro Asp Val Pro   Asp Met Val Thr Ser   Gln Val Thr 
    10400                 10405                 10410             


Ser Ser   Gly Thr Asp Thr Ser   Ile Thr Ile Pro Thr   Leu Thr Leu 
    10415                 10420                 10425             


Ser Ser   Gly Glu Pro Glu Thr   Thr Thr Ser Phe Ile   Thr Tyr Ser 
    10430                 10435                 10440             


Glu Thr   His Thr Ser Ser Ala   Ile Pro Thr Leu Pro   Val Ser Pro 
    10445                 10450                 10455             


Gly Ala   Ser Lys Met Leu Thr   Ser Leu Val Ile Ser   Ser Gly Thr 
    10460                 10465                 10470             


Asp Ser   Thr Thr Thr Phe Pro   Thr Leu Thr Glu Thr   Pro Tyr Glu 
    10475                 10480                 10485             


Pro Glu   Thr Thr Ala Ile Gln   Leu Ile His Pro Ala   Glu Thr Asn 
    10490                 10495                 10500             


Thr Met   Val Pro Arg Thr Thr   Pro Lys Phe Ser His   Ser Lys Ser 
    10505                 10510                 10515             


Asp Thr   Thr Leu Pro Val Ala   Ile Thr Ser Pro Gly   Pro Glu Ala 
    10520                 10525                 10530             


Ser Ser   Ala Val Ser Thr Thr   Thr Ile Ser Pro Asp   Met Ser Asp 
    10535                 10540                 10545             


Leu Val   Thr Ser Leu Val Pro   Ser Ser Gly Thr Asp   Thr Ser Thr 
    10550                 10555                 10560             


Thr Phe   Pro Thr Leu Ser Glu   Thr Pro Tyr Glu Pro   Glu Thr Thr 
    10565                 10570                 10575             


Ala Thr   Trp Leu Thr His Pro   Ala Glu Thr Ser Thr   Thr Val Ser 
    10580                 10585                 10590             


Gly Thr   Ile Pro Asn Phe Ser   His Arg Gly Ser Asp   Thr Ala Pro 
    10595                 10600                 10605             


Ser Met   Val Thr Ser Pro Gly   Val Asp Thr Arg Ser   Gly Val Pro 
    10610                 10615                 10620             


Thr Thr   Thr Ile Pro Pro Ser   Ile Pro Gly Val Val   Thr Ser Gln 
    10625                 10630                 10635             


Val Thr   Ser Ser Ala Thr Asp   Thr Ser Thr Ala Ile   Pro Thr Leu 
    10640                 10645                 10650             


Thr Pro   Ser Pro Gly Glu Pro   Glu Thr Thr Ala Ser   Ser Ala Thr 
    10655                 10660                 10665             


His Pro   Gly Thr Gln Thr Gly   Phe Thr Val Pro Ile   Arg Thr Val 
    10670                 10675                 10680             


Pro Ser   Ser Glu Pro Asp Thr   Met Ala Ser Trp Val   Thr His Pro 
    10685                 10690                 10695             


Pro Gln   Thr Ser Thr Pro Val   Ser Arg Thr Thr Ser   Ser Phe Ser 
    10700                 10705                 10710             


His Ser   Ser Pro Asp Ala Thr   Pro Val Met Ala Thr   Ser Pro Arg 
    10715                 10720                 10725             


Thr Glu   Ala Ser Ser Ala Val   Leu Thr Thr Ile Ser   Pro Gly Ala 
    10730                 10735                 10740             


Pro Glu   Met Val Thr Ser Gln   Ile Thr Ser Ser Gly   Ala Ala Thr 
    10745                 10750                 10755             


Ser Thr   Thr Val Pro Thr Leu   Thr His Ser Pro Gly   Met Pro Glu 
    10760                 10765                 10770             


Thr Thr   Ala Leu Leu Ser Thr   His Pro Arg Thr Glu   Thr Ser Lys 
    10775                 10780                 10785             


Thr Phe   Pro Ala Ser Thr Val   Phe Pro Gln Val Ser   Glu Thr Thr 
    10790                 10795                 10800             


Ala Ser   Leu Thr Ile Arg Pro   Gly Ala Glu Thr Ser   Thr Ala Leu 
    10805                 10810                 10815             


Pro Thr   Gln Thr Thr Ser Ser   Leu Phe Thr Leu Leu   Val Thr Gly 
    10820                 10825                 10830             


Thr Ser   Arg Val Asp Leu Ser   Pro Thr Ala Ser Pro   Gly Val Ser 
    10835                 10840                 10845             


Ala Lys   Thr Ala Pro Leu Ser   Thr His Pro Gly Thr   Glu Thr Ser 
    10850                 10855                 10860             


Thr Met   Ile Pro Thr Ser Thr   Leu Ser Leu Gly Leu   Leu Glu Thr 
    10865                 10870                 10875             


Thr Gly   Leu Leu Ala Thr Ser   Ser Ser Ala Glu Thr   Ser Thr Ser 
    10880                 10885                 10890             


Thr Leu   Thr Leu Thr Val Ser   Pro Ala Val Ser Gly   Leu Ser Ser 
    10895                 10900                 10905             


Ala Ser   Ile Thr Thr Asp Lys   Pro Gln Thr Val Thr   Ser Trp Asn 
    10910                 10915                 10920             


Thr Glu   Thr Ser Pro Ser Val   Thr Ser Val Gly Pro   Pro Glu Phe 
    10925                 10930                 10935             


Ser Arg   Thr Val Thr Gly Thr   Thr Met Thr Leu Ile   Pro Ser Glu 
    10940                 10945                 10950             


Met Pro   Thr Pro Pro Lys Thr   Ser His Gly Glu Gly   Val Ser Pro 
    10955                 10960                 10965             


Thr Thr   Ile Leu Arg Thr Thr   Met Val Glu Ala Thr   Asn Leu Ala 
    10970                 10975                 10980             


Thr Thr   Gly Ser Ser Pro Thr   Val Ala Lys Thr Thr   Thr Thr Phe 
    10985                 10990                 10995             


Asn Thr   Leu Ala Gly Ser Leu   Phe Thr Pro Leu Thr   Thr Pro Gly 
    11000                 11005                 11010             


Met Ser   Thr Leu Ala Ser Glu   Ser Val Thr Ser Arg   Thr Ser Tyr 
    11015                 11020                 11025             


Asn His   Arg Ser Trp Ile Ser   Thr Thr Ser Ser Tyr   Asn Arg Arg 
    11030                 11035                 11040             


Tyr Trp   Thr Pro Ala Thr Ser   Thr Pro Val Thr Ser   Thr Phe Ser 
    11045                 11050                 11055             


Pro Gly   Ile Ser Thr Ser Ser   Ile Pro Ser Ser Thr   Ala Ala Thr 
    11060                 11065                 11070             


Val Pro   Phe Met Val Pro Phe   Thr Leu Asn Phe Thr   Ile Thr Asn 
    11075                 11080                 11085             


Leu Gln   Tyr Glu Glu Asp Met   Arg His Pro Gly Ser   Arg Lys Phe 
    11090                 11095                 11100             


Asn Ala   Thr Glu Arg Glu Leu   Gln Gly Leu Leu Lys   Pro Leu Phe 
    11105                 11110                 11115             


Arg Asn   Ser Ser Leu Glu Tyr   Leu Tyr Ser Gly Cys   Arg Leu Ala 
    11120                 11125                 11130             


Ser Leu   Arg Pro Glu Lys Asp   Ser Ser Ala Thr Ala   Val Asp Ala 
    11135                 11140                 11145             


Ile Cys   Thr His Arg Pro Asp   Pro Glu Asp Leu Gly   Leu Asp Arg 
    11150                 11155                 11160             


Glu Arg   Leu Tyr Trp Glu Leu   Ser Asn Leu Thr Asn   Gly Ile Gln 
    11165                 11170                 11175             


Glu Leu   Gly Pro Tyr Thr Leu   Asp Arg Asn Ser Leu   Tyr Val Asn 
    11180                 11185                 11190             


Gly Phe   Thr His Arg Ser Ser   Met Pro Thr Thr Ser   Thr Pro Gly 
    11195                 11200                 11205             


Thr Ser   Thr Val Asp Val Gly   Thr Ser Gly Thr Pro   Ser Ser Ser 
    11210                 11215                 11220             


Pro Ser   Pro Thr Thr Ala Gly   Pro Leu Leu Met Pro   Phe Thr Leu 
    11225                 11230                 11235             


Asn Phe   Thr Ile Thr Asn Leu   Gln Tyr Glu Glu Asp   Met Arg Arg 
    11240                 11245                 11250             


Thr Gly   Ser Arg Lys Phe Asn   Thr Met Glu Ser Val   Leu Gln Gly 
    11255                 11260                 11265             


Leu Leu   Lys Pro Leu Phe Lys   Asn Thr Ser Val Gly   Pro Leu Tyr 
    11270                 11275                 11280             


Ser Gly   Cys Arg Leu Thr Leu   Leu Arg Pro Glu Lys   Asp Gly Ala 
    11285                 11290                 11295             


Ala Thr   Gly Val Asp Ala Ile   Cys Thr His Arg Leu   Asp Pro Lys 
    11300                 11305                 11310             


Ser Pro   Gly Leu Asn Arg Glu   Gln Leu Tyr Trp Glu   Leu Ser Lys 
    11315                 11320                 11325             


Leu Thr   Asn Asp Ile Glu Glu   Leu Gly Pro Tyr Thr   Leu Asp Arg 
    11330                 11335                 11340             


Asn Ser   Leu Tyr Val Asn Gly   Phe Thr His Gln Ser   Ser Val Ser 
    11345                 11350                 11355             


Thr Thr   Ser Thr Pro Gly Thr   Ser Thr Val Asp Leu   Arg Thr Ser 
    11360                 11365                 11370             


Gly Thr   Pro Ser Ser Leu Ser   Ser Pro Thr Ile Met   Ala Ala Gly 
    11375                 11380                 11385             


Pro Leu   Leu Val Pro Phe Thr   Leu Asn Phe Thr Ile   Thr Asn Leu 
    11390                 11395                 11400             


Gln Tyr   Gly Glu Asp Met Gly   His Pro Gly Ser Arg   Lys Phe Asn 
    11405                 11410                 11415             


Thr Thr   Glu Arg Val Leu Gln   Gly Leu Leu Gly Pro   Ile Phe Lys 
    11420                 11425                 11430             


Asn Thr   Ser Val Gly Pro Leu   Tyr Ser Gly Cys Arg   Leu Thr Ser 
    11435                 11440                 11445             


Leu Arg   Ser Glu Lys Asp Gly   Ala Ala Thr Gly Val   Asp Ala Ile 
    11450                 11455                 11460             


Cys Ile   His His Leu Asp Pro   Lys Ser Pro Gly Leu   Asn Arg Glu 
    11465                 11470                 11475             


Arg Leu   Tyr Trp Glu Leu Ser   Gln Leu Thr Asn Gly   Ile Lys Glu 
    11480                 11485                 11490             


Leu Gly   Pro Tyr Thr Leu Asp   Arg Asn Ser Leu Tyr   Val Asn Gly 
    11495                 11500                 11505             


Phe Thr   His Arg Thr Ser Val   Pro Thr Ser Ser Thr   Pro Gly Thr 
    11510                 11515                 11520             


Ser Thr   Val Asp Leu Gly Thr   Ser Gly Thr Pro Phe   Ser Leu Pro 
    11525                 11530                 11535             


Ser Pro   Ala Thr Ala Gly Pro   Leu Leu Val Leu Phe   Thr Leu Asn 
    11540                 11545                 11550             


Phe Thr   Ile Thr Asn Leu Lys   Tyr Glu Glu Asp Met   His Arg Pro 
    11555                 11560                 11565             


Gly Ser   Arg Lys Phe Asn Thr   Thr Glu Arg Val Leu   Gln Thr Leu 
    11570                 11575                 11580             


Leu Gly   Pro Met Phe Lys Asn   Thr Ser Val Gly Leu   Leu Tyr Ser 
    11585                 11590                 11595             


Gly Cys   Arg Leu Thr Leu Leu   Arg Ser Glu Lys Asp   Gly Ala Ala 
    11600                 11605                 11610             


Thr Gly   Val Asp Ala Ile Cys   Thr His Arg Leu Asp   Pro Lys Ser 
    11615                 11620                 11625             


Pro Gly   Val Asp Arg Glu Gln   Leu Tyr Trp Glu Leu   Ser Gln Leu 
    11630                 11635                 11640             


Thr Asn   Gly Ile Lys Glu Leu   Gly Pro Tyr Thr Leu   Asp Arg Asn 
    11645                 11650                 11655             


Ser Leu   Tyr Val Asn Gly Phe   Thr His Trp Ile Pro   Val Pro Thr 
    11660                 11665                 11670             


Ser Ser   Thr Pro Gly Thr Ser   Thr Val Asp Leu Gly   Ser Gly Thr 
    11675                 11680                 11685             


Pro Ser   Ser Leu Pro Ser Pro   Thr Thr Ala Gly Pro   Leu Leu Val 
    11690                 11695                 11700             


Pro Phe   Thr Leu Asn Phe Thr   Ile Thr Asn Leu Lys   Tyr Glu Glu 
    11705                 11710                 11715             


Asp Met   His Cys Pro Gly Ser   Arg Lys Phe Asn Thr   Thr Glu Arg 
    11720                 11725                 11730             


Val Leu   Gln Ser Leu Leu Gly   Pro Met Phe Lys Asn   Thr Ser Val 
    11735                 11740                 11745             


Gly Pro   Leu Tyr Ser Gly Cys   Arg Leu Thr Leu Leu   Arg Ser Glu 
    11750                 11755                 11760             


Lys Asp   Gly Ala Ala Thr Gly   Val Asp Ala Ile Cys   Thr His Arg 
    11765                 11770                 11775             


Leu Asp   Pro Lys Ser Pro Gly   Val Asp Arg Glu Gln   Leu Tyr Trp 
    11780                 11785                 11790             


Glu Leu   Ser Gln Leu Thr Asn   Gly Ile Lys Glu Leu   Gly Pro Tyr 
    11795                 11800                 11805             


Thr Leu   Asp Arg Asn Ser Leu   Tyr Val Asn Gly Phe   Thr His Gln 
    11810                 11815                 11820             


Thr Ser   Ala Pro Asn Thr Ser   Thr Pro Gly Thr Ser   Thr Val Asp 
    11825                 11830                 11835             


Leu Gly   Thr Ser Gly Thr Pro   Ser Ser Leu Pro Ser   Pro Thr Ser 
    11840                 11845                 11850             


Ala Gly   Pro Leu Leu Val Pro   Phe Thr Leu Asn Phe   Thr Ile Thr 
    11855                 11860                 11865             


Asn Leu   Gln Tyr Glu Glu Asp   Met His His Pro Gly   Ser Arg Lys 
    11870                 11875                 11880             


Phe Asn   Thr Thr Glu Arg Val   Leu Gln Gly Leu Leu   Gly Pro Met 
    11885                 11890                 11895             


Phe Lys   Asn Thr Ser Val Gly   Leu Leu Tyr Ser Gly   Cys Arg Leu 
    11900                 11905                 11910             


Thr Leu   Leu Arg Pro Glu Lys   Asn Gly Ala Ala Thr   Gly Met Asp 
    11915                 11920                 11925             


Ala Ile   Cys Ser His Arg Leu   Asp Pro Lys Ser Pro   Gly Leu Asn 
    11930                 11935                 11940             


Arg Glu   Gln Leu Tyr Trp Glu   Leu Ser Gln Leu Thr   His Gly Ile 
    11945                 11950                 11955             


Lys Glu   Leu Gly Pro Tyr Thr   Leu Asp Arg Asn Ser   Leu Tyr Val 
    11960                 11965                 11970             


Asn Gly   Phe Thr His Arg Ser   Ser Val Ala Pro Thr   Ser Thr Pro 
    11975                 11980                 11985             


Gly Thr   Ser Thr Val Asp Leu   Gly Thr Ser Gly Thr   Pro Ser Ser 
    11990                 11995                 12000             


Leu Pro   Ser Pro Thr Thr Ala   Val Pro Leu Leu Val   Pro Phe Thr 
    12005                 12010                 12015             


Leu Asn   Phe Thr Ile Thr Asn   Leu Gln Tyr Gly Glu   Asp Met Arg 
    12020                 12025                 12030             


His Pro   Gly Ser Arg Lys Phe   Asn Thr Thr Glu Arg   Val Leu Gln 
    12035                 12040                 12045             


Gly Leu   Leu Gly Pro Leu Phe   Lys Asn Ser Ser Val   Gly Pro Leu 
    12050                 12055                 12060             


Tyr Ser   Gly Cys Arg Leu Ile   Ser Leu Arg Ser Glu   Lys Asp Gly 
    12065                 12070                 12075             


Ala Ala   Thr Gly Val Asp Ala   Ile Cys Thr His His   Leu Asn Pro 
    12080                 12085                 12090             


Gln Ser   Pro Gly Leu Asp Arg   Glu Gln Leu Tyr Trp   Gln Leu Ser 
    12095                 12100                 12105             


Gln Met   Thr Asn Gly Ile Lys   Glu Leu Gly Pro Tyr   Thr Leu Asp 
    12110                 12115                 12120             


Arg Asn   Ser Leu Tyr Val Asn   Gly Phe Thr His Arg   Ser Ser Gly 
    12125                 12130                 12135             


Leu Thr   Thr Ser Thr Pro Trp   Thr Ser Thr Val Asp   Leu Gly Thr 
    12140                 12145                 12150             


Ser Gly   Thr Pro Ser Pro Val   Pro Ser Pro Thr Thr   Thr Gly Pro 
    12155                 12160                 12165             


Leu Leu   Val Pro Phe Thr Leu   Asn Phe Thr Ile Thr   Asn Leu Gln 
    12170                 12175                 12180             


Tyr Glu   Glu Asn Met Gly His   Pro Gly Ser Arg Lys   Phe Asn Ile 
    12185                 12190                 12195             


Thr Glu   Ser Val Leu Gln Gly   Leu Leu Lys Pro Leu   Phe Lys Ser 
    12200                 12205                 12210             


Thr Ser   Val Gly Pro Leu Tyr   Ser Gly Cys Arg Leu   Thr Leu Leu 
    12215                 12220                 12225             


Arg Pro   Glu Lys Asp Gly Val   Ala Thr Arg Val Asp   Ala Ile Cys 
    12230                 12235                 12240             


Thr His   Arg Pro Asp Pro Lys   Ile Pro Gly Leu Asp   Arg Gln Gln 
    12245                 12250                 12255             


Leu Tyr   Trp Glu Leu Ser Gln   Leu Thr His Ser Ile   Thr Glu Leu 
    12260                 12265                 12270             


Gly Pro   Tyr Thr Leu Asp Arg   Asp Ser Leu Tyr Val   Asn Gly Phe 
    12275                 12280                 12285             


Thr Gln   Arg Ser Ser Val Pro   Thr Thr Ser Thr Pro   Gly Thr Phe 
    12290                 12295                 12300             


Thr Val   Gln Pro Glu Thr Ser   Glu Thr Pro Ser Ser   Leu Pro Gly 
    12305                 12310                 12315             


Pro Thr   Ala Thr Gly Pro Val   Leu Leu Pro Phe Thr   Leu Asn Phe 
    12320                 12325                 12330             


Thr Ile   Thr Asn Leu Gln Tyr   Glu Glu Asp Met Arg   Arg Pro Gly 
    12335                 12340                 12345             


Ser Arg   Lys Phe Asn Thr Thr   Glu Arg Val Leu Gln   Gly Leu Leu 
    12350                 12355                 12360             


Met Pro   Leu Phe Lys Asn Thr   Ser Val Ser Ser Leu   Tyr Ser Gly 
    12365                 12370                 12375             


Cys Arg   Leu Thr Leu Leu Arg   Pro Glu Lys Asp Gly   Ala Ala Thr 
    12380                 12385                 12390             


Arg Val   Asp Ala Val Cys Thr   His Arg Pro Asp Pro   Lys Ser Pro 
    12395                 12400                 12405             


Gly Leu   Asp Arg Glu Arg Leu   Tyr Trp Lys Leu Ser   Gln Leu Thr 
    12410                 12415                 12420             


His Gly   Ile Thr Glu Leu Gly   Pro Tyr Thr Leu Asp   Arg His Ser 
    12425                 12430                 12435             


Leu Tyr   Val Asn Gly Phe Thr   His Gln Ser Ser Met   Thr Thr Thr 
    12440                 12445                 12450             


Arg Thr   Pro Asp Thr Ser Thr   Met His Leu Ala Thr   Ser Arg Thr 
    12455                 12460                 12465             


Pro Ala   Ser Leu Ser Gly Pro   Met Thr Ala Ser Pro   Leu Leu Val 
    12470                 12475                 12480             


Leu Phe   Thr Ile Asn Phe Thr   Ile Thr Asn Leu Arg   Tyr Glu Glu 
    12485                 12490                 12495             


Asn Met   His His Pro Gly Ser   Arg Lys Phe Asn Thr   Thr Glu Arg 
    12500                 12505                 12510             


Val Leu   Gln Gly Leu Leu Arg   Pro Val Phe Lys Asn   Thr Ser Val 
    12515                 12520                 12525             


Gly Pro   Leu Tyr Ser Gly Cys   Arg Leu Thr Leu Leu   Arg Pro Lys 
    12530                 12535                 12540             


Lys Asp   Gly Ala Ala Thr Lys   Val Asp Ala Ile Cys   Thr Tyr Arg 
    12545                 12550                 12555             


Pro Asp   Pro Lys Ser Pro Gly   Leu Asp Arg Glu Gln   Leu Tyr Trp 
    12560                 12565                 12570             


Glu Leu   Ser Gln Leu Thr His   Ser Ile Thr Glu Leu   Gly Pro Tyr 
    12575                 12580                 12585             


Thr Leu   Asp Arg Asp Ser Leu   Tyr Val Asn Gly Phe   Thr Gln Arg 
    12590                 12595                 12600             


Ser Ser   Val Pro Thr Thr Ser   Ile Pro Gly Thr Pro   Thr Val Asp 
    12605                 12610                 12615             


Leu Gly   Thr Ser Gly Thr Pro   Val Ser Lys Pro Gly   Pro Ser Ala 
    12620                 12625                 12630             


Ala Ser   Pro Leu Leu Val Leu   Phe Thr Leu Asn Phe   Thr Ile Thr 
    12635                 12640                 12645             


Asn Leu   Arg Tyr Glu Glu Asn   Met Gln His Pro Gly   Ser Arg Lys 
    12650                 12655                 12660             


Phe Asn   Thr Thr Glu Arg Val   Leu Gln Gly Leu Leu   Arg Ser Leu 
    12665                 12670                 12675             


Phe Lys   Ser Thr Ser Val Gly   Pro Leu Tyr Ser Gly   Cys Arg Leu 
    12680                 12685                 12690             


Thr Leu   Leu Arg Pro Glu Lys   Asp Gly Thr Ala Thr   Gly Val Asp 
    12695                 12700                 12705             


Ala Ile   Cys Thr His His Pro   Asp Pro Lys Ser Pro   Arg Leu Asp 
    12710                 12715                 12720             


Arg Glu   Gln Leu Tyr Trp Glu   Leu Ser Gln Leu Thr   His Asn Ile 
    12725                 12730                 12735             


Thr Glu   Leu Gly Pro Tyr Ala   Leu Asp Asn Asp Ser   Leu Phe Val 
    12740                 12745                 12750             


Asn Gly   Phe Thr His Arg Ser   Ser Val Ser Thr Thr   Ser Thr Pro 
    12755                 12760                 12765             


Gly Thr   Pro Thr Val Tyr Leu   Gly Ala Ser Lys Thr   Pro Ala Ser 
    12770                 12775                 12780             


Ile Phe   Gly Pro Ser Ala Ala   Ser His Leu Leu Ile   Leu Phe Thr 
    12785                 12790                 12795             


Leu Asn   Phe Thr Ile Thr Asn   Leu Arg Tyr Glu Glu   Asn Met Trp 
    12800                 12805                 12810             


Pro Gly   Ser Arg Lys Phe Asn   Thr Thr Glu Arg Val   Leu Gln Gly 
    12815                 12820                 12825             


Leu Leu   Arg Pro Leu Phe Lys   Asn Thr Ser Val Gly   Pro Leu Tyr 
    12830                 12835                 12840             


Ser Gly   Cys Arg Leu Thr Leu   Leu Arg Pro Glu Lys   Asp Gly Glu 
    12845                 12850                 12855             


Ala Thr   Gly Val Asp Ala Ile   Cys Thr His Arg Pro   Asp Pro Thr 
    12860                 12865                 12870             


Gly Pro   Gly Leu Asp Arg Glu   Gln Leu Tyr Leu Glu   Leu Ser Gln 
    12875                 12880                 12885             


Leu Thr   His Ser Ile Thr Glu   Leu Gly Pro Tyr Thr   Leu Asp Arg 
    12890                 12895                 12900             


Asp Ser   Leu Tyr Val Asn Gly   Phe Thr His Arg Ser   Ser Val Pro 
    12905                 12910                 12915             


Thr Thr   Ser Thr Gly Val Val   Ser Glu Glu Pro Phe   Thr Leu Asn 
    12920                 12925                 12930             


Phe Thr   Ile Asn Asn Leu Arg   Tyr Met Ala Asp Met   Gly Gln Pro 
    12935                 12940                 12945             


Gly Ser   Leu Lys Phe Asn Ile   Thr Asp Asn Val Met   Gln His Leu 
    12950                 12955                 12960             


Leu Ser   Pro Leu Phe Gln Arg   Ser Ser Leu Gly Ala   Arg Tyr Thr 
    12965                 12970                 12975             


Gly Cys   Arg Val Ile Ala Leu   Arg Ser Val Lys Asn   Gly Ala Glu 
    12980                 12985                 12990             


Thr Arg   Val Asp Leu Leu Cys   Thr Tyr Leu Gln Pro   Leu Ser Gly 
    12995                 13000                 13005             


Pro Gly   Leu Pro Ile Lys Gln   Val Phe His Glu Leu   Ser Gln Gln 
    13010                 13015                 13020             


Thr His   Gly Ile Thr Arg Leu   Gly Pro Tyr Ser Leu   Asp Lys Asp 
    13025                 13030                 13035             


Ser Leu   Tyr Leu Asn Gly Tyr   Asn Glu Pro Gly Pro   Asp Glu Pro 
    13040                 13045                 13050             


Pro Thr   Thr Pro Lys Pro Ala   Thr Thr Phe Leu Pro   Pro Leu Ser 
    13055                 13060                 13065             


Glu Ala   Thr Thr Ala Met Gly   Tyr His Leu Lys Thr   Leu Thr Leu 
    13070                 13075                 13080             


Asn Phe   Thr Ile Ser Asn Leu   Gln Tyr Ser Pro Asp   Met Gly Lys 
    13085                 13090                 13095             


Gly Ser   Ala Thr Phe Asn Ser   Thr Glu Gly Val Leu   Gln His Leu 
    13100                 13105                 13110             


Leu Arg   Pro Leu Phe Gln Lys   Ser Ser Met Gly Pro   Phe Tyr Leu 
    13115                 13120                 13125             


Gly Cys   Gln Leu Ile Ser Leu   Arg Pro Glu Lys Asp   Gly Ala Ala 
    13130                 13135                 13140             


Thr Gly   Val Asp Thr Thr Cys   Thr Tyr His Pro Asp   Pro Val Gly 
    13145                 13150                 13155             


Pro Gly   Leu Asp Ile Gln Gln   Leu Tyr Trp Glu Leu   Ser Gln Leu 
    13160                 13165                 13170             


Thr His   Gly Val Thr Gln Leu   Gly Phe Tyr Val Leu   Asp Arg Asp 
    13175                 13180                 13185             


Ser Leu   Phe Ile Asn Gly Tyr   Ala Pro Gln Asn Leu   Ser Ile Arg 
    13190                 13195                 13200             


Gly Glu   Tyr Gln Ile Asn Phe   His Ile Val Asn Trp   Asn Leu Ser 
    13205                 13210                 13215             


Asn Pro   Asp Pro Thr Ser Ser   Glu Tyr Ile Thr Leu   Leu Arg Asp 
    13220                 13225                 13230             


Ile Gln   Asp Lys Val Thr Thr   Leu Tyr Lys Gly Ser   Gln Leu His 
    13235                 13240                 13245             


Asp Thr   Phe Arg Phe Cys Leu   Val Thr Asn Leu Thr   Met Asp Ser 
    13250                 13255                 13260             


Val Leu   Val Thr Val Lys Ala   Leu Phe Ser Ser Asn   Leu Asp Pro 
    13265                 13270                 13275             


Ser Leu   Val Glu Gln Val Phe   Leu Asp Lys Thr Leu   Asn Ala Ser 
    13280                 13285                 13290             


Phe His   Trp Leu Gly Ser Thr   Tyr Gln Leu Val Asp   Ile His Val 
    13295                 13300                 13305             


Thr Glu   Met Glu Ser Ser Val   Tyr Gln Pro Thr Ser   Ser Ser Ser 
    13310                 13315                 13320             


Thr Gln   His Phe Tyr Leu Asn   Phe Thr Ile Thr Asn   Leu Pro Tyr 
    13325                 13330                 13335             


Ser Gln   Asp Lys Ala Gln Pro   Gly Thr Thr Asn Tyr   Gln Arg Asn 
    13340                 13345                 13350             


Lys Arg   Asn Ile Glu Asp Ala   Leu Asn Gln Leu Phe   Arg Asn Ser 
    13355                 13360                 13365             


Ser Ile   Lys Ser Tyr Phe Ser   Asp Cys Gln Val Ser   Thr Phe Arg 
    13370                 13375                 13380             


Ser Val   Pro Asn Arg His His   Thr Gly Val Asp Ser   Leu Cys Asn 
    13385                 13390                 13395             


Phe Ser   Pro Leu Ala Arg Arg   Val Asp Arg Val Ala   Ile Tyr Glu 
    13400                 13405                 13410             


Glu Phe   Leu Arg Met Thr Arg   Asn Gly Thr Gln Leu   Gln Asn Phe 
    13415                 13420                 13425             


Thr Leu   Asp Arg Ser Ser Val   Leu Val Asp Gly Tyr   Ser Pro Asn 
    13430                 13435                 13440             


Arg Asn   Glu Pro Leu Thr Gly   Asn Ser Asp Leu Pro   Phe Trp Ala 
    13445                 13450                 13455             


Val Ile   Leu Ile Gly Leu Ala   Gly Leu Leu Gly Val   Ile Thr Cys 
    13460                 13465                 13470             


Leu Ile   Cys Gly Val Leu Val   Thr Thr Arg Arg Arg   Lys Lys Glu 
    13475                 13480                 13485             


Gly Glu   Tyr Asn Val Gln Gln   Gln Cys Pro Gly Tyr   Tyr Gln Ser 
    13490                 13495                 13500             


His Leu   Asp Leu Glu Asp Leu   Gln 
    13505                 13510     


<210>  9100
<211>  349
<212>  DNA
<213>  Homo sapiens

<400>  9100
gctcccaagc cagccaccac attcctgcct cctctgtcag aagccacaac agccatgggg     60

taccacctga agaccctcac actcaacttc accatctcca atctccagta ttcaccagat    120

atgggcaagg gctcagctac attcaactcc accgaggggg tccttcagca cctgctcaga    180

cccttgttcc agaagagcag catgggcccc ttctacttgg gttgccaact gatctccctc    240

aggctatgca ccccagaatt tatcaatccg gggcgagtac cagataaatt tccacattgt    300

caactggaac ctcagtaatc cagaccccac atcctcagag tacatcacc                349


<210>  9101
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9101

Met Gly Tyr His Leu Lys Thr Leu Thr Leu Asn Phe Thr Ile Ser Asn 
1               5                   10                  15


Leu Gln Tyr Ser Pro Asp Met Gly Lys Gly Ser Ala Thr Phe Asn Ser 
            20                  25                  30


Thr Glu Gly Val Leu Gln His Leu Leu Arg Pro Leu Phe Gln Lys Ser 
        35                  40                  45


Ser Met Gly Pro Phe Tyr Leu Gly Cys Gln Leu Ile Ser Leu Arg Leu 
    50                  55                  60


Cys Thr Pro Glu Phe Ile Asn Pro Gly Arg Val Pro Asp Lys Phe Pro 
65                  70                  75                  80


His Cys Gln Leu Glu Pro Gln 
                85


<210>  9102
<211>  556
<212>  DNA
<213>  Homo sapiens

<400>  9102
aatgttcctg gagcggtgta ggaccaatac tgtatatatg gaaggaaggc aaggtggata     60

gatggaagga agaagtgaca gatggatggg tgaaaggaag gaaagaagtg agagaaggaa    120

gaggaaggat agacagatgt tagaaggtac aatgaaagga aggaagccag caagaaagaa    180

aggatgcatt aatagaatga aagatggaag ggaagaagaa aggatggaaa gagagaagga    240

agaatgaaca gaaggaagtt caagagtggt gaaaagaaga aaggcaggga gagaaggaga    300

accggggtgg tcagcgagga gccattcaca ctgaacttca ccatcaacaa cctgcgctac    360

atggcggaca tgggccaacc cggctccctc aagttcaaca tcacagacaa cgtcatgcag    420

cacctgctca gtcctttgtt ccagaggagc agcctgggtg cacggtacac aggctgcagg    480

gtcatcgcac taaggtctgt gaagaacggt gctgagacac gggtggacct cctctgcacc    540

tacctgcagc ccctca                                                    556


<210>  9103
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  9103

Met Asn Arg Arg Lys Phe Lys Ser Gly Glu Lys Lys Lys Gly Arg Glu 
1               5                   10                  15


Arg Arg Arg Thr Gly Val Val Ser Glu Glu Pro Phe Thr Leu Asn Phe 
            20                  25                  30


Thr Ile Asn Asn Leu Arg Tyr Met Ala Asp Met Gly Gln Pro Gly Ser 
        35                  40                  45


Leu Lys Phe Asn Ile Thr Asp Asn Val Met Gln His Leu Leu Ser Pro 
    50                  55                  60


Leu Phe Gln Arg Ser Ser Leu Gly Ala Arg Tyr Thr Gly Cys Arg Val 
65                  70                  75                  80


Ile Ala Leu Arg Ser Val Lys Asn Gly Ala Glu Thr Arg Val Asp Leu 
                85                  90                  95


Leu Cys Thr Tyr Leu Gln Pro 
            100


<210>  9104
<211>  384
<212>  DNA
<213>  Homo sapiens

<400>  9104
atgggtcacc ctggctccag gaagttcaac atcacggaga gtgttctgca gggtctgctc     60

aagcccttgt tcaagagcac cagtgttggc cctctgtatt ctggctgcag actgaccttg    120

ctcaggcctg agaaggatgg agtagccacc agagtggacg ccatctgcac ccaccgccct    180

gaccccaaaa tccctgggct agacagacag cagctatact gggagctgag ccagctgacc    240

cacagcatca ctgagctggg accctacacc ctggataggg acagtctcta tgtcaatggt    300

ttcacccagc ggagctctgt gcccaccacc agcagtgagt attctactga tgttcccatg    360

gccccaatct tacaacaaac ttag                                           384


<210>  9105
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  9105

Met Gly His Pro Gly Ser Arg Lys Phe Asn Ile Thr Glu Ser Val Leu 
1               5                   10                  15


Gln Gly Leu Leu Lys Pro Leu Phe Lys Ser Thr Ser Val Gly Pro Leu 
            20                  25                  30


Tyr Ser Gly Cys Arg Leu Thr Leu Leu Arg Pro Glu Lys Asp Gly Val 
        35                  40                  45


Ala Thr Arg Val Asp Ala Ile Cys Thr His Arg Pro Asp Pro Lys Ile 
    50                  55                  60


Pro Gly Leu Asp Arg Gln Gln Leu Tyr Trp Glu Leu Ser Gln Leu Thr 
65                  70                  75                  80


His Ser Ile Thr Glu Leu Gly Pro Tyr Thr Leu Asp Arg Asp Ser Leu 
                85                  90                  95


Tyr Val Asn Gly Phe Thr Gln Arg Ser Ser Val Pro Thr Thr Ser Ser 
            100                 105                 110


Glu Tyr Ser Thr Asp Val Pro Met Ala Pro Ile Leu Gln Gln Thr 
        115                 120                 125


<210>  9106
<211>  2079
<212>  DNA
<213>  Homo sapiens

<400>  9106
cgcgtccccg agccccccct caccccgtcc cggaccccct gccccgcagc tcgcgctcgt     60

gccccctccc ccacgccccc ccggggcgcc tgggtgtcga gggaccgagc gccccgcggc    120

gggccagaga agggacgcgc ggcgggcggc cgcggggcat gaggcggagg cgcgatgtcg    180

gtgccgctgc tcaagatcgg ggccgtgctg agcaccatgg ccatggtcac caactggatg    240

tcgcagacgc tgccctcgct cgtggggctc aacggcaccg tgtcccgtgc gggcgcctct    300

gagaaaatca ctctcttcca gaacccagaa gagggctggc agctgtacac ctcagcccag    360

gcccctgacg ggaaatgcat ctgcacggcc gtgatcccag cgcagagtac ctgctctcga    420

gatggcagga gtcgggagct gcggcaactg atggagaagg tccagaacgt ctcccagtcc    480

atggaggtcc ttgagttgcg gacgtatcgc gacctccagt atgtacgcgg catggagacc    540

ctcatgcgga gcctggatgc gcggctccgg gcagctgatg ggtccctctc ggccaagagc    600

ttccaggagc tgaaggacag gatgacggaa ctgttgcccc tgagctcggt cctggagcag    660

tacaaggcag acacgcggac cattgtacgc ttgcgggagg aggtgaggaa tctctccggc    720

agtctggcgg ccattcagga ggagatgggt gcctacgggt atgaggacct gcagcaacgg    780

gtgatggccc tggaggcccg gctccacgcc tgcgcccaga agctgggctg tgggaagctg    840

accggggtca gtaaccccat caccgttcgg gccatggggt cccgcttcgg ctcctggatg    900

actgacacga tggcccccag tgcggatagc cgggtctggt acatggatgg ctattacaaa    960

ggccgccggg tcctggagtt ccgtaccctg ggagacttca tcaaaggcca gaactttatc   1020

cagcacctgc tgccccagcc gtgggcgggc acgggccacg tggtgtacaa cggctccctg   1080

ttctataaca agtaccagag caacgtggtg gtcaaatacc acttccgctc gcgctctgtg   1140

ctggtgcaga ggagcctccc gggcgccggt tacaacaaca ccttccccta ctcctggggc   1200

ggcttctccg acatggactt catggtggac gagagcgggc tctgggctgt gtacaccacc   1260

aaccagaacg cgggcaacat cgtggtcagc cggctggacc cgcacaccct cgaggtcatg   1320

cggtcctggg acaccggcta ccccaagcgc agcgctggcg aggccttcat gatctgcggt   1380

gtgctctacg tgaccaactc ccacctggct ggggccaagg tctacttcgc ctattttacc   1440

aacacgtcca gttacgagta cacggacgtg cccttccaca accagtattc ccacatctcg   1500

atgctggatt acaacccccg ggagcgcgcc ctctatacct ggaacaacgg ccaccaggtg   1560

ctctacaatg tcaccctgtt tcacgtcatc agcacctctg gggacccctg agccaatgct   1620

gtggctcggg ctgctgcctg gggggcctct gggggctggg ggcccttttc attctgcctg   1680

tgtccctcaa gggtgatctc tctgtctctg tcacgccctt tctccccgcc tttttgctgg   1740

gcttttgttc tctgcctatg tatttctgtc tattttttca atttcccctc ttctccttta   1800

ttgatctctg cttttaatac accacttctt tctttctgcc tttttatgga tgtctttttc   1860

tttttatggc tctggttctc cagttctttc cgtctctgcc tctctctgtc tctctctctc   1920

tgtccttcca cccctccctc cttgcttccc acccattcct catccctcac tcccaccccc   1980

acccccaccc ccaggagttg agtgcatgga tctgtttctt tttttattta cactttttct   2040

ttccggtttg ccggaataaa caggaccttt gacatttga                          2079


<210>  9107
<211>  478
<212>  PRT
<213>  Homo sapiens

<400>  9107

Met Ser Val Pro Leu Leu Lys Ile Gly Ala Val Leu Ser Thr Met Ala 
1               5                   10                  15


Met Val Thr Asn Trp Met Ser Gln Thr Leu Pro Ser Leu Val Gly Leu 
            20                  25                  30


Asn Gly Thr Val Ser Arg Ala Gly Ala Ser Glu Lys Ile Thr Leu Phe 
        35                  40                  45


Gln Asn Pro Glu Glu Gly Trp Gln Leu Tyr Thr Ser Ala Gln Ala Pro 
    50                  55                  60


Asp Gly Lys Cys Ile Cys Thr Ala Val Ile Pro Ala Gln Ser Thr Cys 
65                  70                  75                  80


Ser Arg Asp Gly Arg Ser Arg Glu Leu Arg Gln Leu Met Glu Lys Val 
                85                  90                  95


Gln Asn Val Ser Gln Ser Met Glu Val Leu Glu Leu Arg Thr Tyr Arg 
            100                 105                 110


Asp Leu Gln Tyr Val Arg Gly Met Glu Thr Leu Met Arg Ser Leu Asp 
        115                 120                 125


Ala Arg Leu Arg Ala Ala Asp Gly Ser Leu Ser Ala Lys Ser Phe Gln 
    130                 135                 140


Glu Leu Lys Asp Arg Met Thr Glu Leu Leu Pro Leu Ser Ser Val Leu 
145                 150                 155                 160


Glu Gln Tyr Lys Ala Asp Thr Arg Thr Ile Val Arg Leu Arg Glu Glu 
                165                 170                 175


Val Arg Asn Leu Ser Gly Ser Leu Ala Ala Ile Gln Glu Glu Met Gly 
            180                 185                 190


Ala Tyr Gly Tyr Glu Asp Leu Gln Gln Arg Val Met Ala Leu Glu Ala 
        195                 200                 205


Arg Leu His Ala Cys Ala Gln Lys Leu Gly Cys Gly Lys Leu Thr Gly 
    210                 215                 220


Val Ser Asn Pro Ile Thr Val Arg Ala Met Gly Ser Arg Phe Gly Ser 
225                 230                 235                 240


Trp Met Thr Asp Thr Met Ala Pro Ser Ala Asp Ser Arg Val Trp Tyr 
                245                 250                 255


Met Asp Gly Tyr Tyr Lys Gly Arg Arg Val Leu Glu Phe Arg Thr Leu 
            260                 265                 270


Gly Asp Phe Ile Lys Gly Gln Asn Phe Ile Gln His Leu Leu Pro Gln 
        275                 280                 285


Pro Trp Ala Gly Thr Gly His Val Val Tyr Asn Gly Ser Leu Phe Tyr 
    290                 295                 300


Asn Lys Tyr Gln Ser Asn Val Val Val Lys Tyr His Phe Arg Ser Arg 
305                 310                 315                 320


Ser Val Leu Val Gln Arg Ser Leu Pro Gly Ala Gly Tyr Asn Asn Thr 
                325                 330                 335


Phe Pro Tyr Ser Trp Gly Gly Phe Ser Asp Met Asp Phe Met Val Asp 
            340                 345                 350


Glu Ser Gly Leu Trp Ala Val Tyr Thr Thr Asn Gln Asn Ala Gly Asn 
        355                 360                 365


Ile Val Val Ser Arg Leu Asp Pro His Thr Leu Glu Val Met Arg Ser 
    370                 375                 380


Trp Asp Thr Gly Tyr Pro Lys Arg Ser Ala Gly Glu Ala Phe Met Ile 
385                 390                 395                 400


Cys Gly Val Leu Tyr Val Thr Asn Ser His Leu Ala Gly Ala Lys Val 
                405                 410                 415


Tyr Phe Ala Tyr Phe Thr Asn Thr Ser Ser Tyr Glu Tyr Thr Asp Val 
            420                 425                 430


Pro Phe His Asn Gln Tyr Ser His Ile Ser Met Leu Asp Tyr Asn Pro 
        435                 440                 445


Arg Glu Arg Ala Leu Tyr Thr Trp Asn Asn Gly His Gln Val Leu Tyr 
    450                 455                 460


Asn Val Thr Leu Phe His Val Ile Ser Thr Ser Gly Asp Pro 
465                 470                 475


<210>  9108
<211>  2019
<212>  DNA
<213>  Homo sapiens

<400>  9108
cgcaacaaag actcggagcg agcgaggggg cgggggtggg gcggaatccc ggccgccggc     60

gaggcggggg aggcggcggc gcagggtcgc cccggccggg cgggcggggt cgcgcctggt    120

ggcggtcccc gcgccgaggc gccgctaggg cgggcggggg tcgggacgcc gggctagggg    180

cgcgtcatgt ggccgctcac ggtcccgccg ccgctgctgc tgctgctgtg ctcaggcctg    240

gccggacaga ctctcttcca gaacccagaa gagggctggc agctgtacac ctcagcccag    300

gcccctgacg ggaaatgcat ctgcacggcc gtgatcccag cgcagagtac ctgctctcga    360

gatggcagga gtcgggagct gcggcaactg atggagaagg tccagaacgt ctcccagtcc    420

atggaggtcc ttgagttgcg gacgtatcgc gacctccagt atgtacgcgg catggagacc    480

ctcatgcgga gcctggatgc gcggctccgg gcagctgatg ggtccctctc ggccaagagc    540

ttccaggagc tgaaggacag gatgacggaa ctgttgcccc tgagctcggt cctggagcag    600

tacaaggcag acacgcggac cattgtacgc ttgcgggagg aggtgaggaa tctctccggc    660

agtctggcgg ccattcagga ggagatgggt gcctacgggt atgaggacct gcagcaacgg    720

gtgatggccc tggaggcccg gctccacgcc tgcgcccaga agctgggctg tgggaagctg    780

accggggtca gtaaccccat caccgttcgg gccatggggt cccgcttcgg ctcctggatg    840

actgacacga tggcccccag tgcggatagc cgggtctggt acatggatgg ctattacaaa    900

ggccgccggg tcctggagtt ccgtaccctg ggagacttca tcaaaggcca gaactttatc    960

cagcacctgc tgccccagcc gtgggcgggc acgggccacg tggtgtacaa cggctccctg   1020

ttctataaca agtaccagag caacgtggtg gtcaaatacc acttccgctc gcgctctgtg   1080

ctggtgcaga ggagcctccc gggcgccggt tacaacaaca ccttccccta ctcctggggc   1140

ggcttctccg acatggactt catggtggac gagagcgggc tctgggctgt gtacaccacc   1200

aaccagaacg cgggcaacat cgtggtcagc cggctggacc cgcacaccct cgaggtcatg   1260

cggtcctggg acaccggcta ccccaagcgc agcgctggcg aggccttcat gatctgcggt   1320

gtgctctacg tgaccaactc ccacctggct ggggccaagg tctacttcgc ctattttacc   1380

aacacgtcca gttacgagta cacggacgtg cccttccaca accagtattc ccacatctcg   1440

atgctggatt acaacccccg ggagcgcgcc ctctatacct ggaacaacgg ccaccaggtg   1500

ctctacaatg tcaccctgtt tcacgtcatc agcacctctg gggacccctg agccaatgct   1560

gtggctcggg ctgctgcctg gggggcctct gggggctggg ggcccttttc attctgcctg   1620

tgtccctcaa gggtgatctc tctgtctctg tcacgccctt tctccccgcc tttttgctgg   1680

gcttttgttc tctgcctatg tatttctgtc tattttttca atttcccctc ttctccttta   1740

ttgatctctg cttttaatac accacttctt tctttctgcc tttttatgga tgtctttttc   1800

tttttatggc tctggttctc cagttctttc cgtctctgcc tctctctgtc tctctctctc   1860

tgtccttcca cccctccctc cttgcttccc acccattcct catccctcac tcccaccccc   1920

acccccaccc ccaggagttg agtgcatgga tctgtttctt tttttattta cactttttct   1980

ttccggtttg ccggaataaa caggaccttt gacatttga                          2019


<210>  9109
<211>  454
<212>  PRT
<213>  Homo sapiens

<400>  9109

Met Trp Pro Leu Thr Val Pro Pro Pro Leu Leu Leu Leu Leu Cys Ser 
1               5                   10                  15


Gly Leu Ala Gly Gln Thr Leu Phe Gln Asn Pro Glu Glu Gly Trp Gln 
            20                  25                  30


Leu Tyr Thr Ser Ala Gln Ala Pro Asp Gly Lys Cys Ile Cys Thr Ala 
        35                  40                  45


Val Ile Pro Ala Gln Ser Thr Cys Ser Arg Asp Gly Arg Ser Arg Glu 
    50                  55                  60


Leu Arg Gln Leu Met Glu Lys Val Gln Asn Val Ser Gln Ser Met Glu 
65                  70                  75                  80


Val Leu Glu Leu Arg Thr Tyr Arg Asp Leu Gln Tyr Val Arg Gly Met 
                85                  90                  95


Glu Thr Leu Met Arg Ser Leu Asp Ala Arg Leu Arg Ala Ala Asp Gly 
            100                 105                 110


Ser Leu Ser Ala Lys Ser Phe Gln Glu Leu Lys Asp Arg Met Thr Glu 
        115                 120                 125


Leu Leu Pro Leu Ser Ser Val Leu Glu Gln Tyr Lys Ala Asp Thr Arg 
    130                 135                 140


Thr Ile Val Arg Leu Arg Glu Glu Val Arg Asn Leu Ser Gly Ser Leu 
145                 150                 155                 160


Ala Ala Ile Gln Glu Glu Met Gly Ala Tyr Gly Tyr Glu Asp Leu Gln 
                165                 170                 175


Gln Arg Val Met Ala Leu Glu Ala Arg Leu His Ala Cys Ala Gln Lys 
            180                 185                 190


Leu Gly Cys Gly Lys Leu Thr Gly Val Ser Asn Pro Ile Thr Val Arg 
        195                 200                 205


Ala Met Gly Ser Arg Phe Gly Ser Trp Met Thr Asp Thr Met Ala Pro 
    210                 215                 220


Ser Ala Asp Ser Arg Val Trp Tyr Met Asp Gly Tyr Tyr Lys Gly Arg 
225                 230                 235                 240


Arg Val Leu Glu Phe Arg Thr Leu Gly Asp Phe Ile Lys Gly Gln Asn 
                245                 250                 255


Phe Ile Gln His Leu Leu Pro Gln Pro Trp Ala Gly Thr Gly His Val 
            260                 265                 270


Val Tyr Asn Gly Ser Leu Phe Tyr Asn Lys Tyr Gln Ser Asn Val Val 
        275                 280                 285


Val Lys Tyr His Phe Arg Ser Arg Ser Val Leu Val Gln Arg Ser Leu 
    290                 295                 300


Pro Gly Ala Gly Tyr Asn Asn Thr Phe Pro Tyr Ser Trp Gly Gly Phe 
305                 310                 315                 320


Ser Asp Met Asp Phe Met Val Asp Glu Ser Gly Leu Trp Ala Val Tyr 
                325                 330                 335


Thr Thr Asn Gln Asn Ala Gly Asn Ile Val Val Ser Arg Leu Asp Pro 
            340                 345                 350


His Thr Leu Glu Val Met Arg Ser Trp Asp Thr Gly Tyr Pro Lys Arg 
        355                 360                 365


Ser Ala Gly Glu Ala Phe Met Ile Cys Gly Val Leu Tyr Val Thr Asn 
    370                 375                 380


Ser His Leu Ala Gly Ala Lys Val Tyr Phe Ala Tyr Phe Thr Asn Thr 
385                 390                 395                 400


Ser Ser Tyr Glu Tyr Thr Asp Val Pro Phe His Asn Gln Tyr Ser His 
                405                 410                 415


Ile Ser Met Leu Asp Tyr Asn Pro Arg Glu Arg Ala Leu Tyr Thr Trp 
            420                 425                 430


Asn Asn Gly His Gln Val Leu Tyr Asn Val Thr Leu Phe His Val Ile 
        435                 440                 445


Ser Thr Ser Gly Asp Pro 
    450


<210>  9110
<211>  907
<212>  DNA
<213>  Homo sapiens

<400>  9110
cccgccaggc gcgccgagcc gcagcccgcg tccccgagcc ccccctcacc ccgtcccgga     60

ccccctgccc cgcagctcgc gctcgtgccc cctcccccac gcccccccgg ggcgcctggg    120

tgtcgaggga ccgagcgccc cgcggcgggc cagagaaggg acgcgcggcg ggcggccgcg    180

gggcatgagg cggaggcgcg atgtcggtgc cgctgctcaa gatcggggcc gtgctgagca    240

ccatggccat ggtcaccaac tggatgtcgc agacgctgcc ctcgctcgtg gggctcaacg    300

gcaccgtgtc ccgtgcgggc gcctctgaga aaatcactct cttccagaac ccagaagagg    360

gctggcagct gtacacctca gcccaggccc ctgacgggaa atgcatctgc acggccgtga    420

tcccagcgca gagtacctgc tctcgagatg gcaggagtcg ggagctgcgg caactgatgg    480

agaaggtcca gaacgtctcc cagtccatgg aggtccttga gttgcggacg tatcgcgacc    540

tccagtatgt acgcggcatg gagaccctca tgcggagcct ggatgcgcgg ctccgggcag    600

ctgatgggtc cctctcggcc aagagcttcc aggagctgaa ggacaggatg acggaactgt    660

tgcccctgag ctcggtcctg gagcagtaca aggcagacac gcggaccatt gtacgcttgc    720

gggaggaggt gaggaatctc tccggcagtc tggcggccat tcaggaggag atgggtgcct    780

acgggtatga ggacctgcag caacgggtga tggccctgga ggcccggctc cacgcctgcg    840

cccagaagct gggtatgcct tggcccttga ccctgacccc tgatctctga ctgccacacc    900

caactcc                                                              907


<210>  9111
<211>  229
<212>  PRT
<213>  Homo sapiens

<400>  9111

Met Ser Val Pro Leu Leu Lys Ile Gly Ala Val Leu Ser Thr Met Ala 
1               5                   10                  15


Met Val Thr Asn Trp Met Ser Gln Thr Leu Pro Ser Leu Val Gly Leu 
            20                  25                  30


Asn Gly Thr Val Ser Arg Ala Gly Ala Ser Glu Lys Ile Thr Leu Phe 
        35                  40                  45


Gln Asn Pro Glu Glu Gly Trp Gln Leu Tyr Thr Ser Ala Gln Ala Pro 
    50                  55                  60


Asp Gly Lys Cys Ile Cys Thr Ala Val Ile Pro Ala Gln Ser Thr Cys 
65                  70                  75                  80


Ser Arg Asp Gly Arg Ser Arg Glu Leu Arg Gln Leu Met Glu Lys Val 
                85                  90                  95


Gln Asn Val Ser Gln Ser Met Glu Val Leu Glu Leu Arg Thr Tyr Arg 
            100                 105                 110


Asp Leu Gln Tyr Val Arg Gly Met Glu Thr Leu Met Arg Ser Leu Asp 
        115                 120                 125


Ala Arg Leu Arg Ala Ala Asp Gly Ser Leu Ser Ala Lys Ser Phe Gln 
    130                 135                 140


Glu Leu Lys Asp Arg Met Thr Glu Leu Leu Pro Leu Ser Ser Val Leu 
145                 150                 155                 160


Glu Gln Tyr Lys Ala Asp Thr Arg Thr Ile Val Arg Leu Arg Glu Glu 
                165                 170                 175


Val Arg Asn Leu Ser Gly Ser Leu Ala Ala Ile Gln Glu Glu Met Gly 
            180                 185                 190


Ala Tyr Gly Tyr Glu Asp Leu Gln Gln Arg Val Met Ala Leu Glu Ala 
        195                 200                 205


Arg Leu His Ala Cys Ala Gln Lys Leu Gly Met Pro Trp Pro Leu Thr 
    210                 215                 220


Leu Thr Pro Asp Leu 
225


<210>  9112
<211>  711
<212>  DNA
<213>  Homo sapiens

<400>  9112
cgcgcctggt ggcggtcccc gcgccgaggc gccgctaggg cgggcggggg tcgggacgcc     60

gggctagggg cgcgtcatgt ggccgctcac ggtcccgccg ccgctgctgc tgctgctgtg    120

ctcaggcctg gccggacaga ctctcttcca gaacccagaa gagggctggc agctgtacac    180

ctcagcccag gcccctgacg ggaaatgcat ctgcacggcc gtgatcccag cgcagagtac    240

ctgctctcga gatggcagga gtcgggagct gcggcaactg atggagaagg tccagaacgt    300

ctcccagtcc atggaggtcc ttgagttgcg gacgtatcgc gacctccagt atgtacgcgg    360

catggagacc ctcatgcgga gcctggatgc gcggctccgg gcagctgatg ggtccctctc    420

ggccaagagc ttccaggagc tgaaggacag gatgacggaa ctgttgcccc tgagctcggt    480

cctggagcag tacaaggcag acacgcggac cattgtacgc ttgcgggagg aggtgaggaa    540

tctctccggc agtctggcgg ccattcagga ggagatgggt gcctacgggt atgaggacct    600

gcagcaacgg gtgatggccc tggaggcccg gctccacgcc tgcgcccaga agctgggtat    660

gccttggccc ttgaccctga cccctgatct ctgactgcca cacccaactc c             711


<210>  9113
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  9113

Met Trp Pro Leu Thr Val Pro Pro Pro Leu Leu Leu Leu Leu Cys Ser 
1               5                   10                  15


Gly Leu Ala Gly Gln Thr Leu Phe Gln Asn Pro Glu Glu Gly Trp Gln 
            20                  25                  30


Leu Tyr Thr Ser Ala Gln Ala Pro Asp Gly Lys Cys Ile Cys Thr Ala 
        35                  40                  45


Val Ile Pro Ala Gln Ser Thr Cys Ser Arg Asp Gly Arg Ser Arg Glu 
    50                  55                  60


Leu Arg Gln Leu Met Glu Lys Val Gln Asn Val Ser Gln Ser Met Glu 
65                  70                  75                  80


Val Leu Glu Leu Arg Thr Tyr Arg Asp Leu Gln Tyr Val Arg Gly Met 
                85                  90                  95


Glu Thr Leu Met Arg Ser Leu Asp Ala Arg Leu Arg Ala Ala Asp Gly 
            100                 105                 110


Ser Leu Ser Ala Lys Ser Phe Gln Glu Leu Lys Asp Arg Met Thr Glu 
        115                 120                 125


Leu Leu Pro Leu Ser Ser Val Leu Glu Gln Tyr Lys Ala Asp Thr Arg 
    130                 135                 140


Thr Ile Val Arg Leu Arg Glu Glu Val Arg Asn Leu Ser Gly Ser Leu 
145                 150                 155                 160


Ala Ala Ile Gln Glu Glu Met Gly Ala Tyr Gly Tyr Glu Asp Leu Gln 
                165                 170                 175


Gln Arg Val Met Ala Leu Glu Ala Arg Leu His Ala Cys Ala Gln Lys 
            180                 185                 190


Leu Gly Met Pro Trp Pro Leu Thr Leu Thr Pro Asp Leu 
        195                 200                 205


<210>  9114
<211>  777
<212>  DNA
<213>  Homo sapiens

<400>  9114
gcggccactg actttggcca gacgaaccaa aagtttgggt ttgaactggg ccccgtctgc     60

ttcagcagct gagagtgtcc ggggtgggag ggaccatgag ggagccccag aatggggtgc    120

atttggtgct gaggctttga agccaccgta tttttcgtta cctgtgacta tggagccaat    180

gggatgtgac ttcgctcatc acggacagtc attccttctc ctttccaggg tgctgggggc    240

tggggttccc tggcccaagg gtccagcctc ctctcacccc attccaggtg gcatactgca    300

gtctggctct ttctcccctc cctccccacc caagcctcac tggatgtctc ctgatcccag    360

gctgggaccc ctacccccac cccctttgat cctttctact tccacggtga aaggactgag    420

gtcggactac agagggaaga gggacttccc ttgactgggt tgtgtttctt ttcctgcctc    480

agcccagctc tgcaaatccc ctccccctgc cccccacctc cccaggctca ccttgccatg    540

ccaggtggtt tggggaccaa gatgttgggg gggtgaatca ggatcctaat ggtgctgccc    600

tatttatacc tgggtctgta ttaaaaggga aagtcccccc tgttgtagat ttcatctgct    660

tcctccttag ggaaggctgg gatatgatga gagattccag cccaagcctg gccccccacc    720

gccaggccat agggcataat ttgcatctca aatctgagaa taaactgatg aactgtg       777


<210>  9115
<211>  94
<212>  PRT
<213>  Homo sapiens

<400>  9115

Met Glu Pro Met Gly Cys Asp Phe Ala His His Gly Gln Ser Phe Leu 
1               5                   10                  15


Leu Leu Ser Arg Val Leu Gly Ala Gly Val Pro Trp Pro Lys Gly Pro 
            20                  25                  30


Ala Ser Ser His Pro Ile Pro Gly Gly Ile Leu Gln Ser Gly Ser Phe 
        35                  40                  45


Ser Pro Pro Ser Pro Pro Lys Pro His Trp Met Ser Pro Asp Pro Arg 
    50                  55                  60


Leu Gly Pro Leu Pro Pro Pro Pro Leu Ile Leu Ser Thr Ser Thr Val 
65                  70                  75                  80


Lys Gly Leu Arg Ser Asp Tyr Arg Gly Lys Arg Asp Phe Pro 
                85                  90


<210>  9116
<211>  6174
<212>  DNA
<213>  Homo sapiens

<400>  9116
gcgagtgact gcaccgagcc cgagaagtcg ccgcgccccg cagccgcccc gactggttcc     60

ccgccttgcc cgtgggcccc gccgggatgg ggaaccgccg ggacctgggc cagccgcggg    120

ccggtctctg cctgctcctg gccgcgctgc agcttctgcc ggggacgcag gccgatcctg    180

tggatgtcct gaaggccctg ggtgtgcagg gaggccaggc tggggtcccc gaggggcctg    240

gcttctgtcc ccagaggact ccagagggtg accgggcatt cagaattggc caggccagca    300

cgctcggcat ccccacgtgg gaactctttc cagaaggcca ctttcctgag aacttctcct    360

tgctgatcac cttgcgggga cagccagcca atcagtctgt cctgctgtcc atttatgatg    420

aaaggggtgc ccggcagttg ggcctggcac tggggccagc gctgggtctc ctaggtgacc    480

ccttccgccc cctcccccag caggtcaacc tcacagatgg caggtggcac cgtgtggccg    540

tcagcataga tggtgagatg gtgaccctgg tagctgactg tgaagctcag ccccctgttt    600

tgggccatgg cccccgcttc atcagcatag ctggactcac tgtgctgggg acccaggacc    660

ttggggaaaa gactttcgag ggagacattc aggagctgct gataagccca gatcctcagg    720

ctgccttcca ggcttgtgag cggtacctcc ccgactgtga caacctggca ccggcagcca    780

cagtggctcc ccagggtgaa ccagaaaccc ctcgtcctcg gcggaagggg aagggaaaag    840

ggaggaagaa agggcgaggt cgcaagggga agggcaggaa aaagaacaag gaaatttgga    900

cctcaagtcc acctcctgac tccgcagaga accagacctc cactgacatc cccaagacag    960

agactccagc tccaaatctg cctccgaccc ccacgccttt ggtcgtcacc tccactgtga   1020

ctactggact caatgccacg atcctagaga ggagcttgga ccctgacagt ggaaccgagc   1080

tggggaccct ggagaccaag gcagccaggg aggatgaaga aggagatgat tccaccatgg   1140

gccctgactt ccgggcagca gaatatccat ctcggactca gttccagatc tttcctggtg   1200

ctggagagaa aggagcaaaa ggagagcccg cagtgattga aaaggggcag cagtttgagg   1260

gacctccagg agccccagga ccccaagggg tggttggccc ctcaggccct cccggccccc   1320

caggattccc tggcgaccct ggtccaccgg gccctgctgg cctcccagga atccccggca   1380

ttgatgggat ccgaggccca ccgggcactg tgatcatgat gccgttccag tttgcaggcg   1440

gctcctttaa aggcccccca gtctcattcc agcaggccca ggctcaggca gttctgcagc   1500

agactcagct ctctatgaaa ggcccccctg gtccagtggg gctcactggg cgcccaggcc   1560

ctgtgggtct ccccgggcat ccaggtctga aaggagagga gggagcagaa gggccacagg   1620

gtccccgagg cctgcaggga cctcatggac cccctggccg agtgggcaag atgggccgcc   1680

ctggagcaga tggagctcgg ggcctcccag gggacactgg acctaagggt gatcgtggct   1740

tcgatggcct ccctgggctg cctggtgaga agggccaaag gggtgacttt ggccatgtgg   1800

ggcaacccgg tcccccagga gaggatggtg agaggggagc agagggacct ccagggccca   1860

ctggccaggc tggggagccg ggtccacgag gactgcttgg ccccagaggc tctcctggcc   1920

ccacgggtcg cccgggtgtg actggaattg atggtgctcc tggtgccaaa ggcaatgtgg   1980

gtcctccagg agaaccaggc cctccgggac agcagggaaa ccatgggtcc cagggactcc   2040

ccggtcccca gggactcatt ggcactcctg gggagaaggg tccccctgga aacccaggaa   2100

ttccaggcct cccaggatcc gatggccctc tgggtcaccc aggacatgag ggccccacgg   2160

gagagaaagg ggctcagggt ccaccagggt cggcaggccc tccgggctat cctggacctc   2220

ggggagtgaa gggcacttca ggcaaccggg gcctccaggg ggagaaaggc gagaagggag   2280

aggacggctt cccaggcttc aagggcgatg tggggctcaa aggtgatcag gggaaacccg   2340

gagctccagg tccccgggga gaggatggtc ctgaggggcc gaaggggcag gcggggcagg   2400

ctggcgagga ggggccccca ggctcagctg gggagaaggg caagcttggg gtgccaggcc   2460

tcccaggtta tccaggacgc cctggaccta agggatctat tggatttccc ggtcccctgg   2520

gacccatagg agagaaaggg aagtcgggaa agacagggca gccaggcctg gaaggagagc   2580

ggggaccacc aggttcccgt ggagagaggg ggcaaccggg tgccacaggg caaccaggcc   2640

ccaagggcga tgtgggccag gatggagccc ctgggatccc tggagaaaag ggcctccctg   2700

gtctgcaagg ccctccagga ttccctgggc caaagggccc ccctggtcac caaggtaaag   2760

atgggcgacc agggcaccct ggacagagag gagaactggg cttccaaggt cagacaggcc   2820

cgcctggacc agctggtgtc ttaggccctc agggaaagac aggagaagtg ggacctctag   2880

gtgaaagggg gcctccaggc ccccctggac ctcctggtga acaaggtctt cctggcctgg   2940

aaggcagaga gggggccaag ggggaactgg gaccaccagg accccttggg aaagaagggc   3000

cagctggact caggggcttt cccggcccca aagggggccc tggggacccg ggacctactg   3060

gcttaaaggg tgataagggc cccccagggc ccgtgggggc caatggctcc cctggtgagc   3120

gcggtccttt gggcccagca ggaggcattg gacttcctgg ccaaagtggc agcgaaggcc   3180

ccgttggccc tgcaggcaag aaggggtccc ggggagaacg tggcccccct ggccccactg   3240

gcaaagatgg gatcccaggg cccctggggc ctctgggacc ccctggagct gctgggcctt   3300

ctggcgagga aggggacaag ggggatgtgg gtgcccccgg acacaagggg agtaaaggcg   3360

ataaaggaga cgcgggccca cctggacaac cagggatacg gggtcctgca ggacacccag   3420

gtcccccggg agcagacggg gctcaggggc gccggggacc cccaggcctc tttgggcaga   3480

aaggagatga cggagtcaga ggctttgtgg gggtgattgg ccctcctgga ctgcaggggc   3540

tgccaggccc tccgggagag aaaggggagg tcggagacgt cgggtccatg ggtccccatg   3600

gagctccagg tcctcggggt ccccaaggcc ccactggatc agagggcact ccagggctgc   3660

ctggaggagt tggtcagcca ggcgccgtgg gtgagaaggg tgagcgaggg gacgctggag   3720

acccagggcc tccaggagcc ccaggcatcc cggggcccaa gggagacatt ggtgaaaagg   3780

gggactcagg cccatctgga gctgctggac ccccaggcaa gaaaggtccc cctggagagg   3840

atggagccaa agggagcgtg ggccccacgg ggctgcccgg agatctaggg cccccaggag   3900

accctggagt ttcaggcata gatggttccc caggggagaa gggagaccct ggtgatgttg   3960

ggggaccggg tccgcctgga gcttctgggg agcccggcgc ccccgggccc cccggcaaga   4020

ggggtccttc aggccacatg ggtcgagaag gcagagaagg ggagaaaggt gccaaggggg   4080

agccaggtcc tgatgggccc ccagggagga cgggtccaat gggggctaga gggccccctg   4140

gacgtgtggg gcctgagggt cttcgaggga tccctggccc tgtgggtgaa ccaggcctcc   4200

tgggagcccc tggacagatg ggccctcctg gccccctggg gccctctggc ctcccagggc   4260

tgaagggaga cactggcccc aagggggaaa agggccacat tggattgatc ggtctcattg   4320

gccccccggg agaagctggt gagaaaggag atcaggggtt gccaggcgtg cagggacccc   4380

ctggtcccaa gggagaccct ggtccccctg gtcccattgg ctctctgggc caccctgggc   4440

ccccaggtgt ggcgggccct ctaggacaga aaggctcaaa agggtctccg gggtccatgg   4500

gcccccgtgg agacactgga cctgcaggcc caccaggccc cccgggtgcc cctgccgagc   4560

tgcatgggct gcgcaggcgc cggcgcttcg tcccagtccc gcttccagtc gtggagggcg   4620

gcctggagga ggtgctggcc tcgctcacat cgctgagctt ggagctggag cagctgcggc   4680

gtcctcccgg cactgcggag cgcccgggcc tcgtgtgcca cgagctgcac cgcaaccacc   4740

cgcacctgcc tgatggggaa tactggattg accccaacca gggctgcgcg cgggactcgt   4800

tcagggtttt ttgcaacttc acggcgggag gagagacctg cctctatccc gacaagaagt   4860

ttgagatcgt gaaattggcc tcctggtcca aggaaaagcc tggaggctgg tatagcacat   4920

tccgtcgagg gaagaagttc tcctacgtgg acgccgacgg gtccccagtg aatgtcgtgc   4980

agctgaactt cctgaaactg ctgagtgcca cagctcgcca gaacttcacc tactcctgcc   5040

agaatgcagc tgcctggctg gacgaagcca cgggtgacta cagccactcc gcccgcttcc   5100

ttggcaccaa tggagaggag ctgtctttca accagacgac agcagccact gtcagcgtcc   5160

cccaggatgg ctgccggctc cggaaaggac agacgaagac ccttttcgaa ttcagctctt   5220

ctcgagcggg atttctgccc ctgtgggatg tggcggccac tgactttggc cagacgaacc   5280

aaaagtttgg gtttgaactg ggccccgtct gcttcagcag ctgagagtgt ccggggtggg   5340

agggaccatg agggagcccc agaatggggt gcatttggtg ctgaggcttt gaagccaccg   5400

tatttttcgt tacctgtgac tatggagcca atgggatgtg acttcgctca tcacggacag   5460

tcattccttc tcctttccag ggtgctgggg gctggggttc cctggcccaa gggtccagcc   5520

tcctctcacc ccattccagg tggcatactg cagtctggct ctttctcccc tccctcccca   5580

cccaagcctc acctccccac cccttgaacc cccatgcaat gagcttctaa ctcagagctg   5640

atgaacaaaa gcccccccac ccccaatgcc tgcctcctca ctcctccgtc gctgcccttc   5700

acaccttttg gtgctacccc tccccagagt taagcactgg atgtctcctg atcccaggct   5760

gggaccccta cccccacccc ctttgatcct ttctacttcc acggtgaaag gactgaggtc   5820

ggactacaga gggaagaggg acttcccttg actgggttgt gtttcttttc ctgcctcagc   5880

ccagctctgc aaatcccctc cccctgcccc ccacctcccc aggctcacct tgccatgcca   5940

ggtggtttgg ggaccaagat gttggggggg tgaatcagga tcctaatggt gctgccctat   6000

ttatacctgg gtctgtatta aaagggaaag tcccccctgt tgtagatttc atctgcttcc   6060

tccttaggga aggctgggat atgatgagag attccagccc aagcctggcc ccccaccgcc   6120

aggccatagg gcataatttg catctcaaat ctgagaataa actgatgaac tgtg         6174


<210>  9117
<211>  1745
<212>  PRT
<213>  Homo sapiens

<400>  9117

Met Gly Asn Arg Arg Asp Leu Gly Gln Pro Arg Ala Gly Leu Cys Leu 
1               5                   10                  15


Leu Leu Ala Ala Leu Gln Leu Leu Pro Gly Thr Gln Ala Asp Pro Val 
            20                  25                  30


Asp Val Leu Lys Ala Leu Gly Val Gln Gly Gly Gln Ala Gly Val Pro 
        35                  40                  45


Glu Gly Pro Gly Phe Cys Pro Gln Arg Thr Pro Glu Gly Asp Arg Ala 
    50                  55                  60


Phe Arg Ile Gly Gln Ala Ser Thr Leu Gly Ile Pro Thr Trp Glu Leu 
65                  70                  75                  80


Phe Pro Glu Gly His Phe Pro Glu Asn Phe Ser Leu Leu Ile Thr Leu 
                85                  90                  95


Arg Gly Gln Pro Ala Asn Gln Ser Val Leu Leu Ser Ile Tyr Asp Glu 
            100                 105                 110


Arg Gly Ala Arg Gln Leu Gly Leu Ala Leu Gly Pro Ala Leu Gly Leu 
        115                 120                 125


Leu Gly Asp Pro Phe Arg Pro Leu Pro Gln Gln Val Asn Leu Thr Asp 
    130                 135                 140


Gly Arg Trp His Arg Val Ala Val Ser Ile Asp Gly Glu Met Val Thr 
145                 150                 155                 160


Leu Val Ala Asp Cys Glu Ala Gln Pro Pro Val Leu Gly His Gly Pro 
                165                 170                 175


Arg Phe Ile Ser Ile Ala Gly Leu Thr Val Leu Gly Thr Gln Asp Leu 
            180                 185                 190


Gly Glu Lys Thr Phe Glu Gly Asp Ile Gln Glu Leu Leu Ile Ser Pro 
        195                 200                 205


Asp Pro Gln Ala Ala Phe Gln Ala Cys Glu Arg Tyr Leu Pro Asp Cys 
    210                 215                 220


Asp Asn Leu Ala Pro Ala Ala Thr Val Ala Pro Gln Gly Glu Pro Glu 
225                 230                 235                 240


Thr Pro Arg Pro Arg Arg Lys Gly Lys Gly Lys Gly Arg Lys Lys Gly 
                245                 250                 255


Arg Gly Arg Lys Gly Lys Gly Arg Lys Lys Asn Lys Glu Ile Trp Thr 
            260                 265                 270


Ser Ser Pro Pro Pro Asp Ser Ala Glu Asn Gln Thr Ser Thr Asp Ile 
        275                 280                 285


Pro Lys Thr Glu Thr Pro Ala Pro Asn Leu Pro Pro Thr Pro Thr Pro 
    290                 295                 300


Leu Val Val Thr Ser Thr Val Thr Thr Gly Leu Asn Ala Thr Ile Leu 
305                 310                 315                 320


Glu Arg Ser Leu Asp Pro Asp Ser Gly Thr Glu Leu Gly Thr Leu Glu 
                325                 330                 335


Thr Lys Ala Ala Arg Glu Asp Glu Glu Gly Asp Asp Ser Thr Met Gly 
            340                 345                 350


Pro Asp Phe Arg Ala Ala Glu Tyr Pro Ser Arg Thr Gln Phe Gln Ile 
        355                 360                 365


Phe Pro Gly Ala Gly Glu Lys Gly Ala Lys Gly Glu Pro Ala Val Ile 
    370                 375                 380


Glu Lys Gly Gln Gln Phe Glu Gly Pro Pro Gly Ala Pro Gly Pro Gln 
385                 390                 395                 400


Gly Val Val Gly Pro Ser Gly Pro Pro Gly Pro Pro Gly Phe Pro Gly 
                405                 410                 415


Asp Pro Gly Pro Pro Gly Pro Ala Gly Leu Pro Gly Ile Pro Gly Ile 
            420                 425                 430


Asp Gly Ile Arg Gly Pro Pro Gly Thr Val Ile Met Met Pro Phe Gln 
        435                 440                 445


Phe Ala Gly Gly Ser Phe Lys Gly Pro Pro Val Ser Phe Gln Gln Ala 
    450                 455                 460


Gln Ala Gln Ala Val Leu Gln Gln Thr Gln Leu Ser Met Lys Gly Pro 
465                 470                 475                 480


Pro Gly Pro Val Gly Leu Thr Gly Arg Pro Gly Pro Val Gly Leu Pro 
                485                 490                 495


Gly His Pro Gly Leu Lys Gly Glu Glu Gly Ala Glu Gly Pro Gln Gly 
            500                 505                 510


Pro Arg Gly Leu Gln Gly Pro His Gly Pro Pro Gly Arg Val Gly Lys 
        515                 520                 525


Met Gly Arg Pro Gly Ala Asp Gly Ala Arg Gly Leu Pro Gly Asp Thr 
    530                 535                 540


Gly Pro Lys Gly Asp Arg Gly Phe Asp Gly Leu Pro Gly Leu Pro Gly 
545                 550                 555                 560


Glu Lys Gly Gln Arg Gly Asp Phe Gly His Val Gly Gln Pro Gly Pro 
                565                 570                 575


Pro Gly Glu Asp Gly Glu Arg Gly Ala Glu Gly Pro Pro Gly Pro Thr 
            580                 585                 590


Gly Gln Ala Gly Glu Pro Gly Pro Arg Gly Leu Leu Gly Pro Arg Gly 
        595                 600                 605


Ser Pro Gly Pro Thr Gly Arg Pro Gly Val Thr Gly Ile Asp Gly Ala 
    610                 615                 620


Pro Gly Ala Lys Gly Asn Val Gly Pro Pro Gly Glu Pro Gly Pro Pro 
625                 630                 635                 640


Gly Gln Gln Gly Asn His Gly Ser Gln Gly Leu Pro Gly Pro Gln Gly 
                645                 650                 655


Leu Ile Gly Thr Pro Gly Glu Lys Gly Pro Pro Gly Asn Pro Gly Ile 
            660                 665                 670


Pro Gly Leu Pro Gly Ser Asp Gly Pro Leu Gly His Pro Gly His Glu 
        675                 680                 685


Gly Pro Thr Gly Glu Lys Gly Ala Gln Gly Pro Pro Gly Ser Ala Gly 
    690                 695                 700


Pro Pro Gly Tyr Pro Gly Pro Arg Gly Val Lys Gly Thr Ser Gly Asn 
705                 710                 715                 720


Arg Gly Leu Gln Gly Glu Lys Gly Glu Lys Gly Glu Asp Gly Phe Pro 
                725                 730                 735


Gly Phe Lys Gly Asp Val Gly Leu Lys Gly Asp Gln Gly Lys Pro Gly 
            740                 745                 750


Ala Pro Gly Pro Arg Gly Glu Asp Gly Pro Glu Gly Pro Lys Gly Gln 
        755                 760                 765


Ala Gly Gln Ala Gly Glu Glu Gly Pro Pro Gly Ser Ala Gly Glu Lys 
    770                 775                 780


Gly Lys Leu Gly Val Pro Gly Leu Pro Gly Tyr Pro Gly Arg Pro Gly 
785                 790                 795                 800


Pro Lys Gly Ser Ile Gly Phe Pro Gly Pro Leu Gly Pro Ile Gly Glu 
                805                 810                 815


Lys Gly Lys Ser Gly Lys Thr Gly Gln Pro Gly Leu Glu Gly Glu Arg 
            820                 825                 830


Gly Pro Pro Gly Ser Arg Gly Glu Arg Gly Gln Pro Gly Ala Thr Gly 
        835                 840                 845


Gln Pro Gly Pro Lys Gly Asp Val Gly Gln Asp Gly Ala Pro Gly Ile 
    850                 855                 860


Pro Gly Glu Lys Gly Leu Pro Gly Leu Gln Gly Pro Pro Gly Phe Pro 
865                 870                 875                 880


Gly Pro Lys Gly Pro Pro Gly His Gln Gly Lys Asp Gly Arg Pro Gly 
                885                 890                 895


His Pro Gly Gln Arg Gly Glu Leu Gly Phe Gln Gly Gln Thr Gly Pro 
            900                 905                 910


Pro Gly Pro Ala Gly Val Leu Gly Pro Gln Gly Lys Thr Gly Glu Val 
        915                 920                 925


Gly Pro Leu Gly Glu Arg Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly 
    930                 935                 940


Glu Gln Gly Leu Pro Gly Leu Glu Gly Arg Glu Gly Ala Lys Gly Glu 
945                 950                 955                 960


Leu Gly Pro Pro Gly Pro Leu Gly Lys Glu Gly Pro Ala Gly Leu Arg 
                965                 970                 975


Gly Phe Pro Gly Pro Lys Gly Gly Pro Gly Asp Pro Gly Pro Thr Gly 
            980                 985                 990


Leu Lys Gly Asp Lys Gly Pro Pro Gly Pro Val Gly Ala Asn Gly Ser 
        995                 1000                1005


Pro Gly Glu Arg Gly Pro Leu Gly Pro Ala Gly Gly Ile Gly Leu Pro 
    1010                1015                1020


Gly Gln Ser Gly Ser Glu Gly Pro Val Gly Pro Ala Gly Lys Lys Gly 
1025                1030                1035                1040


Ser Arg Gly Glu Arg Gly Pro Pro Gly Pro Thr Gly Lys Asp Gly Ile 
                1045                1050                1055


Pro Gly Pro Leu Gly Pro Leu Gly Pro Pro Gly Ala Ala Gly Pro Ser 
            1060                1065                1070


Gly Glu Glu Gly Asp Lys Gly Asp Val Gly Ala Pro Gly His Lys Gly 
        1075                1080                1085


Ser Lys Gly Asp Lys Gly Asp Ala Gly Pro Pro Gly Gln Pro Gly Ile 
    1090                1095                1100


Arg Gly Pro Ala Gly His Pro Gly Pro Pro Gly Ala Asp Gly Ala Gln 
1105                1110                1115                1120


Gly Arg Arg Gly Pro Pro Gly Leu Phe Gly Gln Lys Gly Asp Asp Gly 
                1125                1130                1135


Val Arg Gly Phe Val Gly Val Ile Gly Pro Pro Gly Leu Gln Gly Leu 
            1140                1145                1150


Pro Gly Pro Pro Gly Glu Lys Gly Glu Val Gly Asp Val Gly Ser Met 
        1155                1160                1165


Gly Pro His Gly Ala Pro Gly Pro Arg Gly Pro Gln Gly Pro Thr Gly 
    1170                1175                1180


Ser Glu Gly Thr Pro Gly Leu Pro Gly Gly Val Gly Gln Pro Gly Ala 
1185                1190                1195                1200


Val Gly Glu Lys Gly Glu Arg Gly Asp Ala Gly Asp Pro Gly Pro Pro 
                1205                1210                1215


Gly Ala Pro Gly Ile Pro Gly Pro Lys Gly Asp Ile Gly Glu Lys Gly 
            1220                1225                1230


Asp Ser Gly Pro Ser Gly Ala Ala Gly Pro Pro Gly Lys Lys Gly Pro 
        1235                1240                1245


Pro Gly Glu Asp Gly Ala Lys Gly Ser Val Gly Pro Thr Gly Leu Pro 
    1250                1255                1260


Gly Asp Leu Gly Pro Pro Gly Asp Pro Gly Val Ser Gly Ile Asp Gly 
1265                1270                1275                1280


Ser Pro Gly Glu Lys Gly Asp Pro Gly Asp Val Gly Gly Pro Gly Pro 
                1285                1290                1295


Pro Gly Ala Ser Gly Glu Pro Gly Ala Pro Gly Pro Pro Gly Lys Arg 
            1300                1305                1310


Gly Pro Ser Gly His Met Gly Arg Glu Gly Arg Glu Gly Glu Lys Gly 
        1315                1320                1325


Ala Lys Gly Glu Pro Gly Pro Asp Gly Pro Pro Gly Arg Thr Gly Pro 
    1330                1335                1340


Met Gly Ala Arg Gly Pro Pro Gly Arg Val Gly Pro Glu Gly Leu Arg 
1345                1350                1355                1360


Gly Ile Pro Gly Pro Val Gly Glu Pro Gly Leu Leu Gly Ala Pro Gly 
                1365                1370                1375


Gln Met Gly Pro Pro Gly Pro Leu Gly Pro Ser Gly Leu Pro Gly Leu 
            1380                1385                1390


Lys Gly Asp Thr Gly Pro Lys Gly Glu Lys Gly His Ile Gly Leu Ile 
        1395                1400                1405


Gly Leu Ile Gly Pro Pro Gly Glu Ala Gly Glu Lys Gly Asp Gln Gly 
    1410                1415                1420


Leu Pro Gly Val Gln Gly Pro Pro Gly Pro Lys Gly Asp Pro Gly Pro 
1425                1430                1435                1440


Pro Gly Pro Ile Gly Ser Leu Gly His Pro Gly Pro Pro Gly Val Ala 
                1445                1450                1455


Gly Pro Leu Gly Gln Lys Gly Ser Lys Gly Ser Pro Gly Ser Met Gly 
            1460                1465                1470


Pro Arg Gly Asp Thr Gly Pro Ala Gly Pro Pro Gly Pro Pro Gly Ala 
        1475                1480                1485


Pro Ala Glu Leu His Gly Leu Arg Arg Arg Arg Arg Phe Val Pro Val 
    1490                1495                1500


Pro Leu Pro Val Val Glu Gly Gly Leu Glu Glu Val Leu Ala Ser Leu 
1505                1510                1515                1520


Thr Ser Leu Ser Leu Glu Leu Glu Gln Leu Arg Arg Pro Pro Gly Thr 
                1525                1530                1535


Ala Glu Arg Pro Gly Leu Val Cys His Glu Leu His Arg Asn His Pro 
            1540                1545                1550


His Leu Pro Asp Gly Glu Tyr Trp Ile Asp Pro Asn Gln Gly Cys Ala 
        1555                1560                1565


Arg Asp Ser Phe Arg Val Phe Cys Asn Phe Thr Ala Gly Gly Glu Thr 
    1570                1575                1580


Cys Leu Tyr Pro Asp Lys Lys Phe Glu Ile Val Lys Leu Ala Ser Trp 
1585                1590                1595                1600


Ser Lys Glu Lys Pro Gly Gly Trp Tyr Ser Thr Phe Arg Arg Gly Lys 
                1605                1610                1615


Lys Phe Ser Tyr Val Asp Ala Asp Gly Ser Pro Val Asn Val Val Gln 
            1620                1625                1630


Leu Asn Phe Leu Lys Leu Leu Ser Ala Thr Ala Arg Gln Asn Phe Thr 
        1635                1640                1645


Tyr Ser Cys Gln Asn Ala Ala Ala Trp Leu Asp Glu Ala Thr Gly Asp 
    1650                1655                1660


Tyr Ser His Ser Ala Arg Phe Leu Gly Thr Asn Gly Glu Glu Leu Ser 
1665                1670                1675                1680


Phe Asn Gln Thr Thr Ala Ala Thr Val Ser Val Pro Gln Asp Gly Cys 
                1685                1690                1695


Arg Leu Arg Lys Gly Gln Thr Lys Thr Leu Phe Glu Phe Ser Ser Ser 
            1700                1705                1710


Arg Ala Gly Phe Leu Pro Leu Trp Asp Val Ala Ala Thr Asp Phe Gly 
        1715                1720                1725


Gln Thr Asn Gln Lys Phe Gly Phe Glu Leu Gly Pro Val Cys Phe Ser 
    1730                1735                1740


Ser 
1745


<210>  9118
<211>  975
<212>  DNA
<213>  Homo sapiens

<400>  9118
ggtctacact gaccacactg acccttcatc ttgatgcctg cactgactct ccatcttaat     60

ggtctacact gatcacccac gctgaccttg gccactgacc actcacgttg tccatcctcc    120

agtcaacccc tcattagctc tcatcatccc accttggtgg cctactctga ccatcccttg    180

acctcatccc tggtaattcc catttgaaat ctgcataatt tcccatttga ccatccccta    240

accacccaca cagacctcga gttcacattt gagaatccct aactgaccct tgctcttctc    300

ccaggggccc tctggcctcc cagggctgaa gggagacact ggccccaagg gggaaaaggg    360

ccacattgga ttgatcggtc tcattggccc cccgggagaa gctggtgaga aaggagatca    420

ggggttgcca ggcgtgcagg gaccccctgg tcccaaggga gaccctggtc cccctggtcc    480

cattggctct ctgggccacc ctgggccccc aggtgtggcg gtgagtatgc agggaatctt    540

ttgtgggatg aggtcactgt ggtggtccag gccaggacct cagctctccc tgtctgtacc    600

ctacagggcc ctctaggaca gaaaggctca aaagggtctc cggtgagtac accctgcttc    660

cgtgggctta cacatcccag ctccccaccc ccttcactgc accagaaccc tccacgtctc    720

tgccttcatt tatttattta ttcatgcaat cgtgcgttcg acaaatattt attcaacacc    780

tacggttgta tttcatcaga tccaaaatgc catcaattat aagatgtacc attattttac    840

aaactgctag gaaagaaaac agttctgcca agtaaactat gacttgccaa agatgttaag    900

aagctgattt cagagacatt aaaacatgaa aagaaaattt gtgtctgatg cctaatgctg    960

aaaactgcat gtctc                                                     975


<210>  9119
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9119

Met Gln Ser Cys Val Arg Gln Ile Phe Ile Gln His Leu Arg Leu Tyr 
1               5                   10                  15


Phe Ile Arg Ser Lys Met Pro Ser Ile Ile Arg Cys Thr Ile Ile Leu 
            20                  25                  30


Gln Thr Ala Arg Lys Glu Asn Ser Ser Ala Lys 
        35                  40


<210>  9120
<211>  1644
<212>  DNA
<213>  Homo sapiens

<400>  9120
ggagctagtg gcctcttcac cctggtgacc tctgttccgt attctgtcac tgagagacgc     60

cctgggacat ctgtggtggc ttttgtcgcg ctgggaccta ccctgactac gggagttggg    120

aggacccggg acaccgcaca gccgggaaat gacagggtct ccctgtcacc caggctggag    180

ttcagtagtg ttctcttggc tcactgaaac tgctgcctcc caagcaaatg atcctcccac    240

ctcagcctcc tgaatagctg ggactacagg tgcacactac catgcccaga ctgagataag    300

gtatgaggaa gccttggcca tgccaccagc cgcttatccc aaattcctga tccctggaag    360

acatctgggc tctccctcct gttccagccc agtagcttcc agcaaaggta ctggctcaat    420

tggacacgga gtgtggaact gcctgctcac acttgtgaac ccccgtccag aaggaagaaa    480

cagaaagggc ccaccttcca gaggccgagg tggctccacc acagcttctg tccggtggtg    540

accagcactg atctccggag ccaagggagg acccgggaca cctgggagcc gggaaatgtt    600

ttccatggct ccgagacaat gacaccgctt cagtgtgaac tctcatgaat tgagtctaga    660

tccccagtgc tgtccgtctc acctgtcctc ctctacacat atctgggata tgtcacggct    720

tggtggtctt tgaagatgtg actctgaact tcatccagaa ggagtaggct ttgctggatt    780

tttccgtgaa gaatctgtag agatgtgatg agggaagcca tcagcacctg gcttctatag    840

ctgcagccca agaggccaac tggaacgtta acatcagaca ctaatccagc tgactggaca    900

caattgggaa aactggttat tttaccaagg ctttaactgg aatggtgtgc cttcctttaa    960

ggaatcaaat ttgacttatg gagccaataa agcccttgga aagctggcct cagatttcat   1020

gtacagtccc tgtacagggt ttccgatctg tgagattttt taaactgaca ggatcatggc   1080

catttcacag acaactaccc aaaaatatct acagacggca ctgctcctac caacccgata   1140

ccagagaact ctctgtcccc tcgtcagcag gaagtagcca gaaagaacat gccgcccctc   1200

gtccttttta taactatgag gtctggattg acagagcaga agcatcacca ttgtggataa   1260

gcgcctcatt ttaaaattca ccttaatcaa aaactgccta aatccaaagg gcatcagcct   1320

aatggctaag gtcagcatga tcacaaacca caaataacat ctccaaccaa aaacattcca   1380

gacacctccc acagagaaat gctagcctcg ggataacccc tctcctgccg gaaagatgtc   1440

acccccaaga taaccacccc tccgcccaga acattccaac cctgccacaa acttctcccc   1500

cacacagaaa cattccaagc ttgtaataag ctccctcacc ctaaaaccaa cgtacattct   1560

tagtctgcaa ggaaaagtgc tcctgactga ccagccagaa tcctctctca ggtcttttct   1620

ataataaacc tgtctttgac tgtc                                          1644


<210>  9121
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  9121

Met Glu Pro Ile Lys Pro Leu Glu Ser Trp Pro Gln Ile Ser Cys Thr 
1               5                   10                  15


Val Pro Val Gln Gly Phe Arg Ser Val Arg Phe Phe Lys Leu Thr Gly 
            20                  25                  30


Ser Trp Pro Phe His Arg Gln Leu Pro Lys Asn Ile Tyr Arg Arg His 
        35                  40                  45


Cys Ser Tyr Gln Pro Asp Thr Arg Glu Leu Ser Val Pro Ser Ser Ala 
    50                  55                  60


Gly Ser Ser Gln Lys Glu His Ala Ala Pro Arg Pro Phe Tyr Asn Tyr 
65                  70                  75                  80


Glu Val Trp Ile Asp Arg Ala Glu Ala Ser Pro Leu Trp Ile Ser Ala 
                85                  90                  95


Ser Phe 



<210>  9122
<211>  2078
<212>  DNA
<213>  Homo sapiens

<400>  9122
gacgttccag gagctagtgg cctcttcacc ctggtgacct ctgttccgta ttctgtcact     60

gagagacgcc ctgggacatc tgtggtggct tttgtcgcgc tgggacctac cctgactacg    120

ggagttggga ggacccggga caccgcacag ccgggaaatg gccctgtgtt atggaacttt    180

ctggggctac cctaagatgc tggaagctgc caatctcatg gagggcctag tggatatcgg    240

cccttgggtc actcttccca gaggacagcc tgaggtgttg gagtggggcc tcccaaagga    300

tcaggactca gtggcctttg aggatgtggc tgtgaacttc acccatgagg agtgggcttt    360

gctgggtcca tcacagaaga atctctacag agatgtgatg cgagaaacca ttaggaacct    420

gaactgtata ggaatgaaat gggaaaacca gaacattgat gatcagcacc aaaatctcag    480

gagaaatcca aggttatcgg agacatggtt acagaatttc attttgatcc attatggtca    540

cctggtagct ttgtctgatg gaggtttgtt acagttttca acaggacagg gtctccctgt    600

cacccaggct ggagttcagt agtgttctct tggctcactg aaactgctgc ctcccaagca    660

aatgatcctc ccacctcagc ctcctgaata gctgggacta caggtgcaca ctaccatgcc    720

cagactgaga taaggtatga ggaagccttg gccatgccac cagccgctta tcccaaattc    780

ctgatccctg gaagacatct gggctctccc tcctgttcca gcccagtagc ttccagcaaa    840

ggtactggct caattggaca cggagtgtgg aactgcctgc tcacacttgt gaacccccgt    900

ccagaaggaa gaaacagaaa gggcccacct tccagaggcc gaggtggctc caccacagct    960

tctgtccggt ggtgaccagc actgatctcc ggagccaagg gaggacccgg gacacctggg   1020

agccgggaaa tgttttccat ggctccgaga caatgacacc gcttcagtgt gaactctcat   1080

gaattgagtc tagatcccca gtgctgtccg tctcacctgt cctcctctac acatatctgg   1140

gatatgtcac ggcttggtgg tctttgaaga tgtgactctg aacttcatcc agaaggagta   1200

ggctttgctg gatttttccg tgaagaatct gtagagatgt gatgagggaa gccatcagca   1260

cctggcttct atagctgcag cccaagaggc caactggaac gttaacatca gacactaatc   1320

cagctgactg gacacaattg ggaaaactgg ttattttacc aaggctttaa ctggaatggt   1380

gtgccttcct ttaaggaatc aaatttgact tatggagcca ataaagccct tggaaagctg   1440

gcctcagatt tcatgtacag tccctgtaca gggtttccga tctgtgagat tttttaaact   1500

gacaggatca tggccatttc acagacaact acccaaaaat atctacagac ggcactgctc   1560

ctaccaaccc gataccagag aactctctgt cccctcgtca gcaggaagta gccagaaaga   1620

acatgccgcc cctcgtcctt tttataacta tgaggtctgg attgacagag cagaagcatc   1680

accattgtgg ataagcgcct cattttaaaa ttcaccttaa tcaaaaactg cctaaatcca   1740

aagggcatca gcctaatggc taaggtcagc atgatcacaa accacaaata acatctccaa   1800

ccaaaaacat tccagacacc tcccacagag aaatgctagc ctcgggataa cccctctcct   1860

gccggaaaga tgtcaccccc aagataacca cccctccgcc cagaacattc caaccctgcc   1920

acaaacttct cccccacaca gaaacattcc aagcttgtaa taagctccct caccctaaaa   1980

ccaacgtaca ttcttagtct gcaaggaaaa gtgctcctga ctgaccagcc agaatcctct   2040

ctcaggtctt ttctataata aacctgtctt tgactgtc                           2078


<210>  9123
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  9123

Met Ala Leu Cys Tyr Gly Thr Phe Trp Gly Tyr Pro Lys Met Leu Glu 
1               5                   10                  15


Ala Ala Asn Leu Met Glu Gly Leu Val Asp Ile Gly Pro Trp Val Thr 
            20                  25                  30


Leu Pro Arg Gly Gln Pro Glu Val Leu Glu Trp Gly Leu Pro Lys Asp 
        35                  40                  45


Gln Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr His Glu 
    50                  55                  60


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Asn Leu Tyr Arg Asp Val 
65                  70                  75                  80


Met Arg Glu Thr Ile Arg Asn Leu Asn Cys Ile Gly Met Lys Trp Glu 
                85                  90                  95


Asn Gln Asn Ile Asp Asp Gln His Gln Asn Leu Arg Arg Asn Pro Arg 
            100                 105                 110


Leu Ser Glu Thr Trp Leu Gln Asn Phe Ile Leu Ile His Tyr Gly His 
        115                 120                 125


Leu Val Ala Leu Ser Asp Gly Gly Leu Leu Gln Phe Ser Thr Gly Gln 
    130                 135                 140


Gly Leu Pro Val Thr Gln Ala Gly Val Gln 
145                 150


<210>  9124
<211>  3743
<212>  DNA
<213>  Homo sapiens

<400>  9124
gacgttccag gagctagtgg cctcttcacc ctggtgacct ctgttccgta ttctgtcact     60

gagagacgcc ctgggacatc tgtggtggct tttgtcgcgc tgggacctac cctgactacg    120

ggagttggga ggacccggga caccgcacag ccgggaaatg gccctgtgtt atggaacttt    180

ctggggctac cctaagatgc tggaagctgc caatctcatg gagggcctag tggatatcgg    240

cccttgggtc actcttccca gaggacagcc tgaggtgttg gagtggggcc tcccaaagga    300

tcaggactca gtggcctttg aggatgtggc tgtgaacttc acccatgagg agtgggcttt    360

gctgggtcca tcacagaaga atctctacag agatgtgatg cgagaaacca ttaggaacct    420

gaactgtata ggaatgaaat gggaaaacca gaacattgat gatcagcacc aaaatctcag    480

gagaaatcca aggtgtgatg tggtagagag atttggtaaa agtaaagatg gtagtcagtg    540

tggagaaacc ttaagccaga ttcgaaatag tattgtaaac aagaacactc ccgccagagt    600

agatgcatgt ggaagcagtg tgaatggaga agtcataatg ggtcattcat ccctgaattg    660

ctacatcaga gttgatactg gacacaaaca ccgggagtgt catgaatatg cagagaagtc    720

atatacacat aagcagtgtg ggaaaggctt aagttatcgc cactcctttc aaacatgtga    780

aaggcctcac actggaaaga aaccctatga ttgtaaggaa tgtggaaaaa ccttcagttc    840

tcctggaaac cttcgaagac atatggtagt aaaaggtgga gatggacctt ataaatgtga    900

attgtgtggg aaagcctttt tttggcccag tttattacgt atgcatgaaa gaactcacac    960

tggagagaaa ccatatgaat gtaagcagtg ttctaaagcc ttccctgttt acagttccta   1020

tctaagacat gaaaaaatac acactgggga gaaaccgtat gaatgtaagc agtgttctaa   1080

agccttccct gattacagtt catatctaag acatgaaaga actcacactg gagagaaacc   1140

ctacaaatgt aaacaatgtg ggaaagcctt cagtgtttcc ggttcccttc gagtacatga   1200

aagaattcac actggagaga aaccctatac atgtaaacag tgtgggaaag cgttttgtca   1260

tcttggaagc tttcaaagac acatgataat gcacagtgga gatggacctc ataaatgtaa   1320

gatatgtggg aaaggctttg attttcctgg ttcagcacga attcatgaag gaactcacac   1380

tctagagaaa ccctatgaat gtaagcaatg tgggaaattg ttatctcatc gctcaagctt   1440

tcgaagacac atgatggcac acactggaga tggccctcat aaatgcacag tatgtgggaa   1500

agcctttgat tctcctagtg tatttcaaag acatgaaagg actcacactg gagagaaacc   1560

ctatgaatgc aagcaatgtg ggaaagcctt ccgtacttcc agttcccttc gaaaacatga   1620

aacaacacac actggagagc aaccctataa atgtaaatgt ggaaaagctt ttagtgattt   1680

attttccttt caaagtcatg aaacaacaca cagtgaagag gagccttatg aatgtaagga   1740

gtgtgggaaa gcatttagtt cttttaaata cttttgtcgc catgaaagga ctcacagtga   1800

agaaaaatct tatgagtgtc aaatttgtgg caaagccttc agtcgtttca gttacttaaa   1860

aactcatgaa aggactcaca cggcagagaa gccatatgaa tgtaagcaat gcaggaaagc   1920

attcttttgg ccctctttcc ttctaagaca tgaaaggact cacactggag aaagacccta   1980

tgaatgtaaa cactgtggta aagccttcag tcgttccagt ttctgtcgag aacatgaaag   2040

aactcacact ggagagaagc cctatgaatg actcagtgac ctttgaagat gtggctgtga   2100

acttcaccca ggaggaatgg actttgctgg atccttcaca gaaaaaactc tacagagacg   2160

tgatgtggga aaccttcagg aacctggcca ctataggaac aaaacaaaaa gaatggaaca   2220

ttgaagagca gtacaaaaac caggggagaa atctcagaaa tcatatggta gagagactct   2280

gtgaaagtaa agaaggtagt catggcggag aaggtttcag ccagattgca aatctcagtc   2340

tgaacaagaa aactccttct ggaggaaagc tttgggaaag cagtgtatgt ggaaaagtct   2400

tgagccatca ttcatccctt aacaggcaca ttagatctta caccagacac aaactgtata   2460

agtgtcagga atatggagag aagccatata aatgtaagaa atgtgggaaa cccttcagtt   2520

atctgcagtc ttttaaaaaa cataaaagaa cacacagtgc agggatagtc tacaaatgta   2580

aggcctgtgg gaaagccttc agttgtcaac gttctttcca aatacatgga aggactcaca   2640

ctggagataa accctttaag tgtaaagaat gtggaaaagc attccgatac caccaatctg   2700

ctcaaaaaca tgaaaaggct catactggag agaaacccta caaatgtaag gaatgtggga   2760

aacccttcat ttaccgccat tctgctcgag cacatgaaag gaatcacact gtacagaaac   2820

gctatgaatg taaacaatgt ggaaaaacct acatatcttc tgtaggtttt caagcacatg   2880

aaagaactca cactggagaa aaaccctatg aatgtaaaaa atgtgggaaa gtgttcgtat   2940

atcacaactc tgctcaaaga catgaaaaga ctcatactgg agagaaaccc tacaaatgca   3000

aggaatgtgg gaaagccttc agttaccact gtactgctca aaaacatgag aggaatcaca   3060

ctgcacagaa acactatgaa tgtaaactgt gtgggaaaac ttacttgtct cctttaggtt   3120

ttcaagcaca tgaaagtact cacactggag ataaaccctt tgagtgtaaa aaatgtggaa   3180

aagcatttag atactactac tcagctcaaa gacatgaaag gactcatact ggagagaaac   3240

cctacaaatg taaggaatgt gggaaagcct tttattgttg cagttctgcc cgaagacatg   3300

aaaggatgca cactgcaaag aaacagtatg aatgtaaaaa atgtgggaaa acatacatta   3360

ctcttgcagg tttccagata catgaaagaa cccacactgg agagaaacct tatgaatgta   3420

aacagtgtgg taaagccttc agtagttcca gttatattca tatacatgaa cgaattcata   3480

ctggagagaa accctatgaa tgtaaagaat gtggaaaacc cttcagtttc cttacaggct   3540

ttcgagtgca catgagaatg cacactggag agaaacctta taaatgtaag gattgtggca   3600

acgccttcat ttggcgtgca tccttacaat accatgtgaa gaaagtgcac gctgaataga   3660

aactataaat gtaaatatcg aaagtttttc aattttaacg attttcaaag ttgatatgaa   3720

agttcatact ggagggtagt tgc                                           3743


<210>  9125
<211>  637
<212>  PRT
<213>  Homo sapiens

<400>  9125

Met Ala Leu Cys Tyr Gly Thr Phe Trp Gly Tyr Pro Lys Met Leu Glu 
1               5                   10                  15


Ala Ala Asn Leu Met Glu Gly Leu Val Asp Ile Gly Pro Trp Val Thr 
            20                  25                  30


Leu Pro Arg Gly Gln Pro Glu Val Leu Glu Trp Gly Leu Pro Lys Asp 
        35                  40                  45


Gln Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr His Glu 
    50                  55                  60


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Asn Leu Tyr Arg Asp Val 
65                  70                  75                  80


Met Arg Glu Thr Ile Arg Asn Leu Asn Cys Ile Gly Met Lys Trp Glu 
                85                  90                  95


Asn Gln Asn Ile Asp Asp Gln His Gln Asn Leu Arg Arg Asn Pro Arg 
            100                 105                 110


Cys Asp Val Val Glu Arg Phe Gly Lys Ser Lys Asp Gly Ser Gln Cys 
        115                 120                 125


Gly Glu Thr Leu Ser Gln Ile Arg Asn Ser Ile Val Asn Lys Asn Thr 
    130                 135                 140


Pro Ala Arg Val Asp Ala Cys Gly Ser Ser Val Asn Gly Glu Val Ile 
145                 150                 155                 160


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Asp Thr Gly His 
                165                 170                 175


Lys His Arg Glu Cys His Glu Tyr Ala Glu Lys Ser Tyr Thr His Lys 
            180                 185                 190


Gln Cys Gly Lys Gly Leu Ser Tyr Arg His Ser Phe Gln Thr Cys Glu 
        195                 200                 205


Arg Pro His Thr Gly Lys Lys Pro Tyr Asp Cys Lys Glu Cys Gly Lys 
    210                 215                 220


Thr Phe Ser Ser Pro Gly Asn Leu Arg Arg His Met Val Val Lys Gly 
225                 230                 235                 240


Gly Asp Gly Pro Tyr Lys Cys Glu Leu Cys Gly Lys Ala Phe Phe Trp 
                245                 250                 255


Pro Ser Leu Leu Arg Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            260                 265                 270


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Pro Val Tyr Ser Ser Tyr 
        275                 280                 285


Leu Arg His Glu Lys Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
    290                 295                 300


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Tyr Leu Arg His Glu 
305                 310                 315                 320


Arg Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys 
                325                 330                 335


Ala Phe Ser Val Ser Gly Ser Leu Arg Val His Glu Arg Ile His Thr 
            340                 345                 350


Gly Glu Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys Ala Phe Cys His 
        355                 360                 365


Leu Gly Ser Phe Gln Arg His Met Ile Met His Ser Gly Asp Gly Pro 
    370                 375                 380


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Phe Pro Gly Ser Ala 
385                 390                 395                 400


Arg Ile His Glu Gly Thr His Thr Leu Glu Lys Pro Tyr Glu Cys Lys 
                405                 410                 415


Gln Cys Gly Lys Leu Leu Ser His Arg Ser Ser Phe Arg Arg His Met 
            420                 425                 430


Met Ala His Thr Gly Asp Gly Pro His Lys Cys Thr Val Cys Gly Lys 
        435                 440                 445


Ala Phe Asp Ser Pro Ser Val Phe Gln Arg His Glu Arg Thr His Thr 
    450                 455                 460


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Phe Arg Thr 
465                 470                 475                 480


Ser Ser Ser Leu Arg Lys His Glu Thr Thr His Thr Gly Glu Gln Pro 
                485                 490                 495


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ser Asp Leu Phe Ser Phe Gln 
            500                 505                 510


Ser His Glu Thr Thr His Ser Glu Glu Glu Pro Tyr Glu Cys Lys Glu 
        515                 520                 525


Cys Gly Lys Ala Phe Ser Ser Phe Lys Tyr Phe Cys Arg His Glu Arg 
    530                 535                 540


Thr His Ser Glu Glu Lys Ser Tyr Glu Cys Gln Ile Cys Gly Lys Ala 
545                 550                 555                 560


Phe Ser Arg Phe Ser Tyr Leu Lys Thr His Glu Arg Thr His Thr Ala 
                565                 570                 575


Glu Lys Pro Tyr Glu Cys Lys Gln Cys Arg Lys Ala Phe Phe Trp Pro 
            580                 585                 590


Ser Phe Leu Leu Arg His Glu Arg Thr His Thr Gly Glu Arg Pro Tyr 
        595                 600                 605


Glu Cys Lys His Cys Gly Lys Ala Phe Ser Arg Ser Ser Phe Cys Arg 
    610                 615                 620


Glu His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu 
625                 630                 635


<210>  9126
<211>  2882
<212>  DNA
<213>  Homo sapiens

<400>  9126
agaattgtca atcaggcgcg aggcagagag gagggtgtga cgttccagga gctagtggcc     60

tcttcaccct ggtgacctct gttccgtatt ctgtcactga gagacgccct gggacatctg    120

tggtggcttt tgtcgcgctg ggacctaccc tgactacggg agttgggagg acccgggaca    180

ccgcacagcc gggaaatgga ctcagtggcc tttgaggatg tggctgtgaa cttcacccat    240

gaggagtggg ctttgctggg tccatcacag aagaatctct acagagatgt gatgcgagaa    300

accattagga acctgaactg tataggaatg aaatgggaaa accagaacat tgatgatcag    360

caccaaaatc tcaggagaaa tccaaggtgt gatgtggtag agagatttgg taaaagtaaa    420

gatggtagtc agtgtggaga aaccttaagc cagattcgaa atagtattgt aaacaagaac    480

actcccgcca gagtagatgc atgtggaagc agtgtgaatg gagaagtcat aatgggtcat    540

tcatccctga attgctacat cagagttgat actggacaca aacaccggga gtgtcatgaa    600

tatgcagaga agtcatatac acataagcag tgtgggaaag gcttaagtta tcgccactcc    660

tttcaaacat gtgaaaggcc tcacactgga aagaaaccct atgattgtaa ggaatgtgga    720

aaaaccttca gttctcctgg aaaccttcga agacatatgg tagtaaaagg tggagatgga    780

ccttataaat gtgaattgtg tgggaaagcc tttttttggc ccagtttatt acgtatgcat    840

gaaagaactc acactggaga gaaaccatat gaatgtaagc agtgttctaa agccttccct    900

gtttacagtt cctatctaag acatgaaaaa atacacactg gggagaaacc gtatgaatgt    960

aagcagtgtt ctaaagcctt ccctgattac agttcatatc taagacatga aagaactcac   1020

actggagaga aaccctacaa atgtaaacaa tgtgggaaag ccttcagtgt ttccggttcc   1080

cttcgagtac atgaaagaat tcacactgga gagaaaccct atacatgtaa acagtgtggg   1140

aaagcgtttt gtcatcttgg aagctttcaa agacacatga taatgcacag tggagatgga   1200

cctcataaat gtaagatatg tgggaaaggc tttgattttc ctggttcagc acgaattcat   1260

gaaggaactc acactctaga gaaaccctat gaatgtaagc aatgtgggaa attgttatct   1320

catcgctcaa gctttcgaag acacatgatg gcacacactg gagatggccc tcataaatgc   1380

acagtatgtg ggaaagcctt tgattctcct agtgtatttc aaagacatga aaggactcac   1440

actggagaga aaccctatga atgcaagcaa tgtgggaaag ccttccgtac ttccagttcc   1500

cttcgaaaac atgaaacaac acacactgga gagcaaccct ataaatgtaa atgtggaaaa   1560

gcttttagtg atttattttc ctttcaaagt catgaaacaa cacacagtga agaggagcct   1620

tatgaatgta aggagtgtgg gaaagcattt agttctttta aatacttttg tcgccatgaa   1680

aggactcaca gtgaagaaaa atcttatgag tgtcaaattt gtggcaaagc cttcagtcgt   1740

ttcagttact taaaaactca tgaaaggact cacacggcag agaagccata tgaatgtaag   1800

caatgcagga aagcattctt ttggccctct ttccttctaa gacatgaaag gactcacact   1860

ggagaaagac cctatgaatg taaacactgt ggtaaagcct tcagtcgttc cagtttctgt   1920

cgagaacatg aaagaactca cactggagag aagccctatg aatgactcag tgacctttga   1980

agatgtggct gtgaacttca cccaggagga atggactttg ctggatcctt cacagaaaaa   2040

actctacaga gacgtgatgt gggaaacctt caggaacctg gccactatag gaacaaaaca   2100

aaaagaatgg aacattgaag agcagtacaa aaaccagggg agaaatctca gaaatcatat   2160

ggtagagaga ctctgtgaaa gtaaagaagg tagtcatggc ggagaaggtt tcagccagat   2220

tgcaaatctc agtctgaaca agaaaactcc ttctggagga aagctttggg aaagcagtgt   2280

atgtggaaaa gtcttgagcc atcattcatc ccttaacagg cacattagat cttacaccag   2340

acacaaactg tataagtgtc aggaatatgg agagaagcca tataaatgta agaaatgtgg   2400

gaaacccttc agttatctgc agtcttttaa aaaacataaa agaacacaca gtgcagggat   2460

agtctacaaa tgtaaggcct gtgggaaagc cttcagttgt caacgttctt tccaaataca   2520

tggaaggact cacactggag ataaaccctt taagtgtaaa gaatgtggaa aagcattccg   2580

ataccaccaa tctgctcaaa aacatgaaaa ggctcatact ggagagaaac cctacaaatg   2640

taaggaatgt gggaaaccct tcatttaccg ccattctgct cgagcacatg aaaggaatca   2700

cactgtacag aaacgctatg aatgtaaaca atgtggaaaa acctacatat cttctgtagg   2760

ttttcaagca catgaaagaa ctcacactgg agaaaaaccc tatgaatgta aaaaatgtgg   2820

gaaagtgttc gtatatcaca actctgctca aagacatgaa aagactcata ctggagagaa   2880

ac                                                                  2882


<210>  9127
<211>  589
<212>  PRT
<213>  Homo sapiens

<400>  9127

Met Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr His Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Asn Leu Tyr Arg Asp Val 
            20                  25                  30


Met Arg Glu Thr Ile Arg Asn Leu Asn Cys Ile Gly Met Lys Trp Glu 
        35                  40                  45


Asn Gln Asn Ile Asp Asp Gln His Gln Asn Leu Arg Arg Asn Pro Arg 
    50                  55                  60


Cys Asp Val Val Glu Arg Phe Gly Lys Ser Lys Asp Gly Ser Gln Cys 
65                  70                  75                  80


Gly Glu Thr Leu Ser Gln Ile Arg Asn Ser Ile Val Asn Lys Asn Thr 
                85                  90                  95


Pro Ala Arg Val Asp Ala Cys Gly Ser Ser Val Asn Gly Glu Val Ile 
            100                 105                 110


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Asp Thr Gly His 
        115                 120                 125


Lys His Arg Glu Cys His Glu Tyr Ala Glu Lys Ser Tyr Thr His Lys 
    130                 135                 140


Gln Cys Gly Lys Gly Leu Ser Tyr Arg His Ser Phe Gln Thr Cys Glu 
145                 150                 155                 160


Arg Pro His Thr Gly Lys Lys Pro Tyr Asp Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Thr Phe Ser Ser Pro Gly Asn Leu Arg Arg His Met Val Val Lys Gly 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Glu Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu Arg Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Pro Val Tyr Ser Ser Tyr 
225                 230                 235                 240


Leu Arg His Glu Lys Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Tyr Leu Arg His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ser Val Ser Gly Ser Leu Arg Val His Glu Arg Ile His Thr 
    290                 295                 300


Gly Glu Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys Ala Phe Cys His 
305                 310                 315                 320


Leu Gly Ser Phe Gln Arg His Met Ile Met His Ser Gly Asp Gly Pro 
                325                 330                 335


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Phe Pro Gly Ser Ala 
            340                 345                 350


Arg Ile His Glu Gly Thr His Thr Leu Glu Lys Pro Tyr Glu Cys Lys 
        355                 360                 365


Gln Cys Gly Lys Leu Leu Ser His Arg Ser Ser Phe Arg Arg His Met 
    370                 375                 380


Met Ala His Thr Gly Asp Gly Pro His Lys Cys Thr Val Cys Gly Lys 
385                 390                 395                 400


Ala Phe Asp Ser Pro Ser Val Phe Gln Arg His Glu Arg Thr His Thr 
                405                 410                 415


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Phe Arg Thr 
            420                 425                 430


Ser Ser Ser Leu Arg Lys His Glu Thr Thr His Thr Gly Glu Gln Pro 
        435                 440                 445


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ser Asp Leu Phe Ser Phe Gln 
    450                 455                 460


Ser His Glu Thr Thr His Ser Glu Glu Glu Pro Tyr Glu Cys Lys Glu 
465                 470                 475                 480


Cys Gly Lys Ala Phe Ser Ser Phe Lys Tyr Phe Cys Arg His Glu Arg 
                485                 490                 495


Thr His Ser Glu Glu Lys Ser Tyr Glu Cys Gln Ile Cys Gly Lys Ala 
            500                 505                 510


Phe Ser Arg Phe Ser Tyr Leu Lys Thr His Glu Arg Thr His Thr Ala 
        515                 520                 525


Glu Lys Pro Tyr Glu Cys Lys Gln Cys Arg Lys Ala Phe Phe Trp Pro 
    530                 535                 540


Ser Phe Leu Leu Arg His Glu Arg Thr His Thr Gly Glu Arg Pro Tyr 
545                 550                 555                 560


Glu Cys Lys His Cys Gly Lys Ala Phe Ser Arg Ser Ser Phe Cys Arg 
                565                 570                 575


Glu His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu 
            580                 585


<210>  9128
<211>  310
<212>  DNA
<213>  Homo sapiens

<400>  9128
aatcaggcgc gaggcagaga ggagggtgtg acgttccagg agctagtggc ctcttcaccc     60

tggtgacctc tgttccgtat tctgtcactg agagacgccc tgggacatct gtggtggctt    120

ttgtcgcgct gggacctacc ctgactacgg gagttgggag gacccgggac accgcacagc    180

cgggaaatgg actcagtgac ctttgaagat gtggctgtga acttcaccca ggaggaatgg    240

actttgctgg atccttcaca gaaaaaactc tacagagacg tgatgtggga aaccttcagg    300

aacctggcca                                                           310


<210>  9129
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9129

Met Asp Ser Val Thr Phe Glu Asp Val Ala Val Asn Phe Thr Gln Glu 
1               5                   10                  15


Glu Trp Thr Leu Leu Asp Pro Ser Gln Lys Lys Leu Tyr Arg Asp Val 
            20                  25                  30


Met Trp Glu Thr Phe Arg Asn Leu 
        35                  40


<210>  9130
<211>  517
<212>  DNA
<213>  Homo sapiens

<400>  9130
gacgttccag gagctagtgg cctcttcacc ctggtgacct ctgttccgta ttctgtcact     60

gagagacgcc ctgggacatc tgtggtggct tttgtcgcgc tgggacctac cctgactacg    120

ggagttggga ggacccggga caccgcacag ccgggaaatg gccctgtgtt atggaacttt    180

ctggggctac cctaagatgc tggaagctgc caatctcatg gagggcctag tggatatcgg    240

cccttgggtc actcttccca gaggacagcc tgaggtgttg gagtggggcc tcccaaagga    300

tcaggctgga gaacttggga cagtggataa gtctggactc agtggccttt gaggatgtgg    360

ctgtgaactt cacccatgag gagtgggctt tgctgggtcc atcacagaag aatctctaca    420

gagatgtgat gcgagaaacc attaggaacc tgaactgtat aggaatgaaa tgggaaaacc    480

agaacattga tgatcagcac caaaatctca ggagaaa                             517


<210>  9131
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  9131

Met Ala Leu Cys Tyr Gly Thr Phe Trp Gly Tyr Pro Lys Met Leu Glu 
1               5                   10                  15


Ala Ala Asn Leu Met Glu Gly Leu Val Asp Ile Gly Pro Trp Val Thr 
            20                  25                  30


Leu Pro Arg Gly Gln Pro Glu Val Leu Glu Trp Gly Leu Pro Lys Asp 
        35                  40                  45


Gln Ala Gly Glu Leu Gly Thr Val Asp Lys Ser Gly Leu Ser Gly Leu 
    50                  55                  60


<210>  9132
<211>  1119
<212>  DNA
<213>  Homo sapiens

<400>  9132
gcgggttcct gagaattgtc aatcaggcgc gaggcagaga ggagggtgtg acgttccagg     60

agctagtggc ctcttcaccc tggtgacctc tgttccgtat tctgtcactg agagacgccc    120

tgggacatct gtggtggctt ttgtcgcgct gggacctacc ctgactacgg gagttgggag    180

gacccgggac accgcacagc cgggaaatgg ccctgtgtta tggaactttc tggggctacc    240

ctaagatgct ggaagctgcc aatctcatgg agggcctagt ggatatcggc ccttgggtca    300

ctcttcccag aggacagcct gaggtgttgg agtggggcct cccaaaggat caggctggag    360

aacttgggac agtggataag tctggtctgt tcctgttatc tggacttggc agattaatgc    420

aacattctgt gggactttgc aatagctaaa gaacttaaat atcctttgtt tactaaaggc    480

ttcattatta tggaagtagt aactgatgtt tattatctga gatggataga tacttgtgct    540

tttcttgttg agctataaaa tagaagtgac ttacaatttc cttccctcct gtaaacactg    600

aatttgagtg attttgatag attcatcaca catggagttt tgtttgtttg ttttatgttt    660

taaatccacg taaggcatga aagggtaagc aaatggcctt gactggggtg gagaggcttg    720

aggccagtga ctccaagtgg aggccaattt tgagcctgca aagggaggtc attgtgggcc    780

cagtttagtt ggttcttcct ggggagcctc ccctgcaggt gtcccagcct aatcactcca    840

gcaatgggag gagaatccct tgaacccagg aggcggaggc tgcagtgggt gacagagcga    900

gattccgtct caaggaaaaa aaaagaagaa tgtgtatata tgtggacagt gaagactcat    960

ggggatgagg gaggttattt ggtggataat gggggttgct ccagggatgg atgcactgaa   1020

aggcctgact ttacaaggca atatatcaat gtagtaaaat tgcactggta ctccatgaat   1080

atatatatat aatttataca tatatgtgta tatatatat                          1119


<210>  9133
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  9133

Met Gly Gly Glu Ser Leu Glu Pro Arg Arg Arg Arg Leu Gln Trp Val 
1               5                   10                  15


Thr Glu Arg Asp Ser Val Ser Arg Lys Lys Lys Glu Glu Cys Val Tyr 
            20                  25                  30


Met Trp Thr Val Lys Thr His Gly Asp Glu Gly Gly Tyr Leu Val Asp 
        35                  40                  45


Asn Gly Gly Cys Ser Arg Asp Gly Cys Thr Glu Arg Pro Asp Phe Thr 
    50                  55                  60


Arg Gln Tyr Ile Asn Val Val Lys Leu His Trp Tyr Ser Met Asn Ile 
65                  70                  75                  80


Tyr Ile 



<210>  9134
<211>  374
<212>  DNA
<213>  Homo sapiens

<400>  9134
aaaaaaaaaa aaaaaaaaaa acctaacctc tgggacattg acattttttt ccccaagcct     60

agtttccatt ccttggtgac gcatggctta tcagaaaatt ggatggtgtt attcagggga    120

caagacaaat gatttctgcc ttctggactc tctccgactg tgaagctaga aaactgtttc    180

taaaaactga aaaacccacc caatgaggtt ttgcatgagc ctgaaaaaga cataaggcag    240

tgtctcctag gaatgtggtt gctgagcact tcaatgagca ccgtggggct ggcggatgtg    300

ccaggctgga gaacttggga cagtggataa gtctggtctg ttcctgttat ctggacttgg    360

cagattaatg caac                                                      374


<210>  9135
<211>  47
<212>  PRT
<213>  Homo sapiens

<400>  9135

Lys Arg His Lys Ala Val Ser Pro Arg Asn Val Val Ala Glu His Phe 
1               5                   10                  15


Asn Glu His Arg Gly Ala Gly Gly Cys Ala Arg Leu Glu Asn Leu Gly 
            20                  25                  30


Gln Trp Ile Ser Leu Val Cys Ser Cys Tyr Leu Asp Leu Ala Asp 
        35                  40                  45


<210>  9136
<211>  2756
<212>  DNA
<213>  Homo sapiens

<400>  9136
gccaggttca aagagcccgc ggcgtcttca cgcccctgcg ctcagctcta gactcagtcg     60

ctcgctgaga gacgccctgg aacgtctgtg tagcctcagt cgctgagaga cgccctggaa    120

cgtctgtggc agcctctgtc acagtgggac ccgcactggc agcgggaggc agagggagga    180

ccctggaaca tcccggaagc cgggaaatgg acgcagtggc ctttgaggat gtggctgtga    240

acttcaccca ggaggaatgg gctttgctgg gtccatcaca gaagaattta tacagatatg    300

tgatgcaaga aaccatcagg aacctggact gtataagaat gatatgggaa gaacagaata    360

ctgaagatca gtacaaaaat cctaggagaa atctaagatg tcatatggta gagagattca    420

gtgaaagtaa agacagtagt cagtgtggag aaacatttag cctcattcga gatagtattg    480

tgaacaacag catttgtcct ggagaagatc catgtcaaag cgctgagtgt gaagaagtca    540

taatgggtca tttatccctt aatagccaca tcagagttga ttctggacac aaaccacatg    600

agtatcagga atatggagag aagccacata cacataaaca acgtgggaaa gccttcagtt    660

accatcactc ctttcagtcg cgtggaaggc ctcacactgg aaagaaacgc tatgagtgta    720

aggaatgtgg aaaaaccttc agttctcgta gaaaccttcg aagacacatg gtagtgcaag    780

gtggaaatag accttataaa tgtaagttgt gtgggaaagc ttttttttgg cccagtttat    840

tacgtatgca tgaaagaact cacactggag agaaaccgta tgaatgtaag cagtgttcta    900

aagcctttcc tttttacagt tcctatcgaa gacatgagag aatgcacact ggggagaaac    960

cgtatgaatg taagcagtgt tctaaagcct tgcctgattc cagttcctat ataagacatg   1020

aaagaactca cactggagag aaaccatata catgtaaaca gtgtgggaaa gccttcagtg   1080

tttccagttc ccttcgaaga catgaaacca ctcacagtgc agagaaaccc tatgagtgta   1140

agcaatgcgg gaaaacattt catcatcttg gaagctttca gatacacatg aaaaggcaca   1200

ctggagatcg acctcataaa tgtaagatat gtgggaaagg ctttgatcgt cccagtttag   1260

ttcgatatca tgaacgaatt cacactggag agaaacccta tgaatgcaag cagtgtggga   1320

aaacgttatc tcatagctca agctttcgaa gacacatgat aatgcacact ggaggtggac   1380

ctcataaatg caagatatgt gggaaagctt ttgtttatcc tagtgtatgt caaagacacg   1440

aaaagtctca cagtggagag aaaccctatg aatgcaagca gtgtgggaaa gcgttatctc   1500

atagctcaag ctttcgaaga catatggtaa tgcatacggg agatgggccg aataaatgca   1560

aggtatgtgg gaaagccttt gtttatccca gtgtatgtca aagacatgaa aagactcact   1620

ggagagaaac aatatgaatg taaactatta taaagccttc tatatttcca gttccctttg   1680

atatcatgaa taaacttaca ctggacagaa accctataaa tgtaaatgtg ggaaagcctt   1740

tcataatttt tattcctttc aaaatcatga aatatctcac actggagaga tgctgtatga   1800

tataaggaat gtgggaaagt gatcgatttt tttttaacac cattgtcaac ataaaacaac   1860

tcacagagca gaaaaactct gtgagtgtaa aatatgtagg gaagccttca gtcattttgg   1920

taacttaaaa gtacatgagg ctgggcacag tggctcacgc ctgtaatccc agcacttagg   1980

gtgggcaaat tgcttgacct caggaatttg aggcctgcct gggcaaaatg gtgaaaccat   2040

gtctctacaa aaaatagaaa aagtagcagg tgtggtggta tgcccctgta gtcccagcta   2100

cttgggaggc tgaggtggga agatctcttg agcccaaggg gtgggggttg cagtgagcca   2160

agatgcactg caccccagcc tgggcgacag agccagaccc tgtctcaaaa aaaaaaaaaa   2220

agtacatgaa aggattcact ctggagagaa gtcatatgaa tgtaagaaat gtagaaaagc   2280

attgagttct ctcaggtcct tgcatagaca taaaaggact cactggagag atactctata   2340

aatgtgtgaa atgtagggaa gtattcttta atgttatttc atttcagata gaaataattc   2400

tcattggaga taaaccctat gaatgtaaac acatagtaaa gccttaattt taagcctcag   2460

tttctttcaa atacagttat cccctaatat ttgcaggagc gtggttctac caccccctgg   2520

gcatacataa atcgacacat gccaagtcct tttttaaaaa tgacatattt ggtacaaaat   2580

tacccggatg tgatggcaca tgcctgtaat cccagctact caggaggctg aggcaggata   2640

atcacttgaa tccgggaggc ggaggttgcg gtgagccaag atcgcgccac tgcactccag   2700

cctgggcagc aagagcaaaa caacctctgt cacacacaca aaaaaaaaaa aaaagg       2756


<210>  9137
<211>  476
<212>  PRT
<213>  Homo sapiens

<400>  9137

Met Asp Ala Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr Gln Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Asn Leu Tyr Arg Tyr Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Ile Arg Met Ile Trp Glu 
        35                  40                  45


Glu Gln Asn Thr Glu Asp Gln Tyr Lys Asn Pro Arg Arg Asn Leu Arg 
    50                  55                  60


Cys His Met Val Glu Arg Phe Ser Glu Ser Lys Asp Ser Ser Gln Cys 
65                  70                  75                  80


Gly Glu Thr Phe Ser Leu Ile Arg Asp Ser Ile Val Asn Asn Ser Ile 
                85                  90                  95


Cys Pro Gly Glu Asp Pro Cys Gln Ser Ala Glu Cys Glu Glu Val Ile 
            100                 105                 110


Met Gly His Leu Ser Leu Asn Ser His Ile Arg Val Asp Ser Gly His 
        115                 120                 125


Lys Pro His Glu Tyr Gln Glu Tyr Gly Glu Lys Pro His Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His His Ser Phe Gln Ser Arg Gly 
145                 150                 155                 160


Arg Pro His Thr Gly Lys Lys Arg Tyr Glu Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Thr Phe Ser Ser Arg Arg Asn Leu Arg Arg His Met Val Val Gln Gly 
            180                 185                 190


Gly Asn Arg Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu Arg Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Pro Phe Tyr Ser Ser Tyr 
225                 230                 235                 240


Arg Arg His Glu Arg Met His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Leu Pro Asp Ser Ser Ser Tyr Ile Arg His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ser Val Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Ser 
    290                 295                 300


Ala Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Thr Phe His His 
305                 310                 315                 320


Leu Gly Ser Phe Gln Ile His Met Lys Arg His Thr Gly Asp Arg Pro 
                325                 330                 335


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Arg Pro Ser Leu Val 
            340                 345                 350


Arg Tyr His Glu Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
        355                 360                 365


Gln Cys Gly Lys Thr Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
    370                 375                 380


Ile Met His Thr Gly Gly Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
385                 390                 395                 400


Ala Phe Val Tyr Pro Ser Val Cys Gln Arg His Glu Lys Ser His Ser 
                405                 410                 415


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Leu Ser His 
            420                 425                 430


Ser Ser Ser Phe Arg Arg His Met Val Met His Thr Gly Asp Gly Pro 
        435                 440                 445


Asn Lys Cys Lys Val Cys Gly Lys Ala Phe Val Tyr Pro Ser Val Cys 
    450                 455                 460


Gln Arg His Glu Lys Thr His Trp Arg Glu Thr Ile 
465                 470                 475


<210>  9138
<211>  2085
<212>  DNA
<213>  Homo sapiens

<400>  9138
ctgtcaatca ggcgcacggc tggcagtagg gtgccaggtt caaagagccc gcggcgtctt     60

cacgcccctg cgctcagctc tagactcagt cgctcgctga gagacgccct ggaacgtctg    120

tgtagcctca gtcgctgaga gacgccctgg aacgtctgtg gcagcctctg tcacagtggg    180

acccgcactg gcagcgggag gcagagggag gaccctggaa catcccggaa gccgggaaat    240

ggacgcagtg gcctttgagg atgtggctgt gaacttcacc caggaggaat gggctttgct    300

gggtccatca cagaagaatt tatacagata tgtgatgcaa gaaaccatca ggaacctgga    360

ctgtataaga atgatatggg aagaacagaa tactgaagat cagtacaaaa atcctaggag    420

aaatctaaga tgtcatatgg tagagagatt cagtgaaagt aaagacagta gtcagtgtgg    480

agaaacattt agcctcattc gagatagtat tgtgaacaac agcatttgtc ctggagaaga    540

tccatgtcaa agcgctgagt gtgaagaagt cataatgggt catttatccc ttaatagcca    600

catcagagtt gattctggac acaaaccaca tgagtatcag gaatatggag agaagccaca    660

tacacataaa caacgtggga aagccttcag ttaccatcac tcctttcagt cgcgtggaag    720

gcctcacact ggaaagaaac gctatgagtg taaggaatgt ggaaaaacct tcagttctcg    780

tagaaacctt cgaagacaca tggtagtgca aggtggaaat agaccttata aatttcctat    840

cgaagacatg agagaatgca cactggggag aaaccgtatg aatgtaagca gtgttctaaa    900

gccttgcctg attccagttc ctatataaga catgaaagaa ctcacactgg agaagaaaca    960

atatgaatgt aaactattat aaagccttct atatttccag ttccctttga tatcatgaat   1020

aaacttacac tggacagaaa ccctataaat gtaaatgtgg gaaagccttt cataattttt   1080

attcctttca aaatcatgaa atatctcaca ctggagagat gctgtatgat ataaggaatg   1140

tgggaaagtg atcgattttt ttttaacacc attgtcaaca taaaacaact cacagagcag   1200

aaaaactctg tgagtgtaaa atatgtaggg aagccttcag tcattttggt aacttaaaag   1260

tacatgaggc tgggcacagt ggctcacgcc tgtaatccca gcacttaggg tgggcaaatt   1320

gcttgacctc aggaatttga ggcctgcctg ggcaaaatgg tgaaaccatg tctctacaaa   1380

aaatagaaaa agtagcaggt gtggtggtat gcccctgtag tcccagctac ttgggaggct   1440

gaggtgggaa gatctcttga gcccaagggg tgggggttgc agtgagccaa gatgcactgc   1500

accccagcct gggcgacaga gccagaccct gtctcaaaaa aaaaaaaaaa gtacatgaaa   1560

ggattcactc tggagagaag tcatatgaat gtaagaaatg tagaaaagca ttgagttctc   1620

tcaggtcctt gcatagacat aaaaggactc actggagaga tactctataa atgtgtgaaa   1680

tgtagggaag tattctttaa tgttatttca tttcagatag aaataattct cattggagat   1740

aaaccctatg aatgtaaaca catagtaaag ccttaatttt aagcctcagt ttctttcaaa   1800

tacagttatc ccctaatatt tgcaggagcg tggttctacc accccctggg catacataaa   1860

tcgacacatg ccaagtcctt ttttaaaaat gacatatttg gtacaaaatt acccggatgt   1920

gatggcacat gcctgtaatc ccagctactc aggaggctga ggcaggataa tcacttgaat   1980

ccgggaggcg gaggttgcgg tgagccaaga tcgcgccact gcactccagc ctgggcagca   2040

agagcaaaac aacctctgtc acacacacaa aaaaaaaaaa aaagg                   2085


<210>  9139
<211>  229
<212>  PRT
<213>  Homo sapiens

<400>  9139

Met Asp Ala Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr Gln Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Asn Leu Tyr Arg Tyr Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Ile Arg Met Ile Trp Glu 
        35                  40                  45


Glu Gln Asn Thr Glu Asp Gln Tyr Lys Asn Pro Arg Arg Asn Leu Arg 
    50                  55                  60


Cys His Met Val Glu Arg Phe Ser Glu Ser Lys Asp Ser Ser Gln Cys 
65                  70                  75                  80


Gly Glu Thr Phe Ser Leu Ile Arg Asp Ser Ile Val Asn Asn Ser Ile 
                85                  90                  95


Cys Pro Gly Glu Asp Pro Cys Gln Ser Ala Glu Cys Glu Glu Val Ile 
            100                 105                 110


Met Gly His Leu Ser Leu Asn Ser His Ile Arg Val Asp Ser Gly His 
        115                 120                 125


Lys Pro His Glu Tyr Gln Glu Tyr Gly Glu Lys Pro His Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His His Ser Phe Gln Ser Arg Gly 
145                 150                 155                 160


Arg Pro His Thr Gly Lys Lys Arg Tyr Glu Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Thr Phe Ser Ser Arg Arg Asn Leu Arg Arg His Met Val Val Gln Gly 
            180                 185                 190


Gly Asn Arg Pro Tyr Lys Phe Pro Ile Glu Asp Met Arg Glu Cys Thr 
        195                 200                 205


Leu Gly Arg Asn Arg Met Asn Val Ser Ser Val Leu Lys Pro Cys Leu 
    210                 215                 220


Ile Pro Val Pro Ile 
225


<210>  9140
<211>  1415
<212>  DNA
<213>  Homo sapiens

<400>  9140
gaattagtga ccagagttcc tcactgggat ctcaggctgc tgtcttcaag actggcgcag     60

aggacgcagt ggcctttgag gatgtggctg tgaacttcac ccaggaggaa tgggctttgc    120

tgggtccatc acagaagaat ttatacagat atgtgatgca agaaaccatc aggaacctgg    180

actgtataag aatgatatgg gaagaacaga atactgaaga tcagtacaaa aatcctagga    240

gaaatctaag ccacatcaga gttgattctg gacacaaacc acatgagtat caggaatatg    300

gagagaagcc acatacacat aaacaacgtg ggaaagcctt cagttaccat cactcctttc    360

agtcgcgtgg aaggcctcac actggaaaga aacgctatga gtgtaaggaa tgtggaaaaa    420

ccttcagttc tcgtagaaac cttcgaagac acatggtagt gcaaggtgga aatagacctt    480

ataaatgtaa gttgtgtggg aaagcttttt tttggcccag tttattacgt atgcatgaaa    540

gaactcacac tggagagaaa ccgtatgaat gtaagcagtg ttctaaagcc tttccttttt    600

acagttccta tcgaagacat gagagaatgc acactgggga gaaaccgtat gaatgtaagc    660

agtgttctaa agccttgcct gattccagtt cctatataag acatgaaaga actcacactg    720

gagagaaacc atatacatgt aaacagtgtg ggaaagcctt cagtgtttcc agttcccttc    780

gaagacatga aaccactcac agtgcagaga aaccctatga gtgtaagcaa tgcgggaaaa    840

catttcatca tcttggaagc tttcagatac acatgaaaag gcacactgga gatcgacctc    900

ataaatgtaa gatatgtggg aaaggctttg atcgtcccag tttagttcga tatcatgaac    960

gaattcacac tggagagaaa ccctatgaat gcaagcagtg tgggaaaacg ttatctcata   1020

gctcaagctt tcgaagacac atgataatgc acactggagg tggacctcat aaatgcaaga   1080

tatgtgggaa agcttttgtt tatcctagtg tatgtcaaag acacgaaaag tctcacagtg   1140

gagagaaacc ctatgaatgc aagcagtgtg ggaaagcgtt atctcatagc tcaagctttc   1200

gaagacatat ggtaatgcat acgggagatg ggccgaataa atgcaaggta tgtgggaaag   1260

cctttgttta tcccagtgta tgtcaaagac atgaaaagac tcactggaga gaaacaatat   1320

gaatgtaaac tattataaag ccttctatat ttccagttcc ctttgatatc atgaataaac   1380

ttacactgga cagaaaccct ataaatgtaa atgtg                              1415


<210>  9141
<211>  388
<212>  PRT
<213>  Homo sapiens

<400>  9141

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Ile Arg Met Ile Trp Glu 
1               5                   10                  15


Glu Gln Asn Thr Glu Asp Gln Tyr Lys Asn Pro Arg Arg Asn Leu Ser 
            20                  25                  30


His Ile Arg Val Asp Ser Gly His Lys Pro His Glu Tyr Gln Glu Tyr 
        35                  40                  45


Gly Glu Lys Pro His Thr His Lys Gln Arg Gly Lys Ala Phe Ser Tyr 
    50                  55                  60


His His Ser Phe Gln Ser Arg Gly Arg Pro His Thr Gly Lys Lys Arg 
65                  70                  75                  80


Tyr Glu Cys Lys Glu Cys Gly Lys Thr Phe Ser Ser Arg Arg Asn Leu 
                85                  90                  95


Arg Arg His Met Val Val Gln Gly Gly Asn Arg Pro Tyr Lys Cys Lys 
            100                 105                 110


Leu Cys Gly Lys Ala Phe Phe Trp Pro Ser Leu Leu Arg Met His Glu 
        115                 120                 125


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Ser Lys 
    130                 135                 140


Ala Phe Pro Phe Tyr Ser Ser Tyr Arg Arg His Glu Arg Met His Thr 
145                 150                 155                 160


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Ser Lys Ala Leu Pro Asp 
                165                 170                 175


Ser Ser Ser Tyr Ile Arg His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Thr Cys Lys Gln Cys Gly Lys Ala Phe Ser Val Ser Ser Ser Leu 
        195                 200                 205


Arg Arg His Glu Thr Thr His Ser Ala Glu Lys Pro Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Gly Lys Thr Phe His His Leu Gly Ser Phe Gln Ile His Met 
225                 230                 235                 240


Lys Arg His Thr Gly Asp Arg Pro His Lys Cys Lys Ile Cys Gly Lys 
                245                 250                 255


Gly Phe Asp Arg Pro Ser Leu Val Arg Tyr His Glu Arg Ile His Thr 
            260                 265                 270


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Thr Leu Ser His 
        275                 280                 285


Ser Ser Ser Phe Arg Arg His Met Ile Met His Thr Gly Gly Gly Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Ala Phe Val Tyr Pro Ser Val Cys 
305                 310                 315                 320


Gln Arg His Glu Lys Ser His Ser Gly Glu Lys Pro Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Val Met His Thr Gly Asp Gly Pro Asn Lys Cys Lys Val Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Cys Gln Arg His Glu Lys Thr His Trp 
    370                 375                 380


Arg Glu Thr Ile 
385


<210>  9142
<211>  1605
<212>  DNA
<213>  Homo sapiens

<400>  9142
aacatcccgg aagccgggaa atgaattagt gaccagagtt cctcactggg atctcaggct     60

gctgtcttca agactggcgc agaggacgca gtggcctttg aggatgtggc tgtgaacttc    120

acccaggagg aatgggcttt gctgggtcca tcacagaaga atttatacag atatgtgatg    180

caagaaacca tcaggaacct ggactgtata agaatgatat gggaagaaca gaatactgaa    240

gatcagtaca aaaatcctag gagaaatcta agatgtcata tggtagagag attcagtgaa    300

agtaaagaca gtagtcagtg tggagaaaca tttagcctca ttcgagatag tattgtgaac    360

aacagcattt gtcctggaga agatccatgt caaagcgctg agtgtgaaga agtcataatg    420

ggtcatttat cccttaatag ccacatcaga gttgattctg gacacaaacc acatgagtat    480

caggaatatg gagagaagcc acatacacat aaacaacgtg ggaaagcctt cagttaccat    540

cactcctttc agtcgcgtgg aaggcctcac actggaaaga aacgctatga gtgtaaggaa    600

tgtggaaaaa ccttcagttc tcgtagaaac cttcgaagac acatggtagt gcaaggtgga    660

aatagacctt ataaatgtaa gttgtgtggg aaagcttttt tttggcccag tttattacgt    720

atgcatgaaa gaactcacac tggagagaaa ccgtatgaat gtaagcagtg ttctaaagcc    780

tttccttttt acagttccta tcgaagacat gagagaatgc acactgggga gaaaccgtat    840

gaatgtaagc agtgttctaa agccttgcct gattccagtt cctatataag acatgaaaga    900

actcacactg gagagaaacc atatacatgt aaacagtgtg ggaaagcctt cagtgtttcc    960

agttcccttc gaagacatga aaccactcac agtgcagaga aaccctatga gtgtaagcaa   1020

tgcgggaaaa catttcatca tcttggaagc tttcagatac acatgaaaag gcacactgga   1080

gatcgacctc ataaatgtaa gatatgtggg aaaggctttg atcgtcccag tttagttcga   1140

tatcatgaac gaattcacac tggagagaaa ccctatgaat gcaagcagtg tgggaaaacg   1200

ttatctcata gctcaagctt tcgaagacac atgataatgc acactggagg tggacctcat   1260

aaatgcaaga tatgtgggaa agcttttgtt tatcctagtg tatgtcaaag acacgaaaag   1320

tctcacagtg gagagaaacc ctatgaatgc aagcagtgtg ggaaagcgtt atctcatagc   1380

tcaagctttc gaagacatat ggtaatgcat acgggagatg ggccgaataa atgcaaggta   1440

tgtgggaaag cctttgttta tcccagtgta tgtcaaagac atgaaaagac tcactggaga   1500

gaaacaatat gaatgtaaac tattataaag ccttctatat ttccagttcc ctttgatatc   1560

atgaataaac ttacactgga cagaaaccct ataaatgtaa atgtg                   1605


<210>  9143
<211>  444
<212>  PRT
<213>  Homo sapiens

<400>  9143

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Ile Arg Met Ile Trp Glu 
1               5                   10                  15


Glu Gln Asn Thr Glu Asp Gln Tyr Lys Asn Pro Arg Arg Asn Leu Arg 
            20                  25                  30


Cys His Met Val Glu Arg Phe Ser Glu Ser Lys Asp Ser Ser Gln Cys 
        35                  40                  45


Gly Glu Thr Phe Ser Leu Ile Arg Asp Ser Ile Val Asn Asn Ser Ile 
    50                  55                  60


Cys Pro Gly Glu Asp Pro Cys Gln Ser Ala Glu Cys Glu Glu Val Ile 
65                  70                  75                  80


Met Gly His Leu Ser Leu Asn Ser His Ile Arg Val Asp Ser Gly His 
                85                  90                  95


Lys Pro His Glu Tyr Gln Glu Tyr Gly Glu Lys Pro His Thr His Lys 
            100                 105                 110


Gln Arg Gly Lys Ala Phe Ser Tyr His His Ser Phe Gln Ser Arg Gly 
        115                 120                 125


Arg Pro His Thr Gly Lys Lys Arg Tyr Glu Cys Lys Glu Cys Gly Lys 
    130                 135                 140


Thr Phe Ser Ser Arg Arg Asn Leu Arg Arg His Met Val Val Gln Gly 
145                 150                 155                 160


Gly Asn Arg Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
                165                 170                 175


Pro Ser Leu Leu Arg Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Pro Phe Tyr Ser Ser Tyr 
        195                 200                 205


Arg Arg His Glu Arg Met His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Ser Lys Ala Leu Pro Asp Ser Ser Ser Tyr Ile Arg His Glu 
225                 230                 235                 240


Arg Thr His Thr Gly Glu Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
                245                 250                 255


Ala Phe Ser Val Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Ser 
            260                 265                 270


Ala Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Thr Phe His His 
        275                 280                 285


Leu Gly Ser Phe Gln Ile His Met Lys Arg His Thr Gly Asp Arg Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Arg Pro Ser Leu Val 
305                 310                 315                 320


Arg Tyr His Glu Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Thr Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Ile Met His Thr Gly Gly Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Cys Gln Arg His Glu Lys Ser His Ser 
    370                 375                 380


Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Leu Ser His 
385                 390                 395                 400


Ser Ser Ser Phe Arg Arg His Met Val Met His Thr Gly Asp Gly Pro 
                405                 410                 415


Asn Lys Cys Lys Val Cys Gly Lys Ala Phe Val Tyr Pro Ser Val Cys 
            420                 425                 430


Gln Arg His Glu Lys Thr His Trp Arg Glu Thr Ile 
        435                 440


<210>  9144
<211>  2797
<212>  DNA
<213>  Homo sapiens

<400>  9144
gaagccctgg caggtcagtg gcaggcactg tcacgctgag tcctatgctg gcagcgggga     60

accttgggga gaacacggga caccgcggaa gccgggaaat gattgtgcgg ctgtaaccgg    120

cacaggttcg cggtccgagt cactgcaccg agactccaag gcctgcagca gaaacagttt    180

aataggggga gaggagagaa gaccccagtt ccgcctccat gagaggtttg gggatggggg    240

tgtttagggg tctggacagg ggcggctgaa gtgtggggtc gctggttggt ggggaagtga    300

caggcgaatc ctgggacggg aggtgaagaa accgcattct cctgctgagt gggttccctc    360

gtggggtttt caccctgctt ggcgccagcc tttccgttgg aattcaagat ctgagaaaga    420

acttgggcaa ctcgagcagc tctccgagat cttatcccca ggcacaatgc agaagccggc    480

ggtcagtgtc ttctgtgacc tgactctcag gaaggcggcc cccgcgaggc agtggggctc    540

aggtttccat tccttgggga cacacggctg gtcagccagt tgaatgattg tatttggggg    600

agaagacaga agtgatctct tccttcctga ctctcagact aatgaagaga gaaaacaata    660

tgattcagta gcctttgagg atgtggcggt gaacttcacc caggaagagt gggctttgct    720

gggtccatca cagaagagtc tgtacagaga tgtgatgtgg gaaaccatta ggaacctgga    780

ctgtatagga atgaaatggg aagacacaaa cattgaagat cagcacagaa atcccaggag    840

gagcctaaga tgtcatatca tagagagatt tagtgaaagt cgccagccag atagtactgt    900

gaatgaaaaa cctcctggag tagatccatg taaaagcagt gtgtgtggag aaatcatggg    960

ttgttcattc cttaattgct atatcacatt tgatgctgga cacaaaccag atgagtgtca   1020

ggaatatgga gagaagccac atacacataa acaatgtggg acagccttca attatcacca   1080

ctcctttcaa acacaggaaa gacctcacac tggaaagaaa cgctatgatt gtaaggaatg   1140

tgggaaaacc ttcagttctt cgggaaacct tcgaagacac ataatagtac aacgtggagg   1200

tggaccttat atatgtaagt tgtgtgggaa agcctttttt tggcctagtt tatttcgtat   1260

gcatgaaaga actcacactg gagagaaacc gtatgaatgt aagcagtgtt gtaaagcctt   1320

ccctatttac agttcctatc taagacatga aagaacacac actggggaga aaccatatga   1380

atgcaagcac tgttccaaag ccttccctga ttacagttcc tatgtaagac atgaaagaac   1440

tcacactgga gaaaaaccct ataaatgtaa acgatgtgga agagccttca gtgtttccag   1500

ttcccttcga atacatgaaa gaactcacac tggagagaaa ccctatgaat gcaagcaatg   1560

cgggaaagca tttcatcatc tgggaagctt tcaaagacac atgataaggc acactggaga   1620

tggacctcat aaatgtaaga tatgtgggaa aggctttgat tgtcctagtt cactgcaaag   1680

tcatgaaaga actcacactg gagagaaacc ctatgaatgc aagcagtgtg ggaaagcgtt   1740

atctcatcac tcaagctttc gaagtcatat gataatgcac actggagatg gacctcacaa   1800

atgcaaggta tgtgggaaag ccttcattta tcccagtgta tttcaaggac atgaaaggac   1860

tcatactggt gagaaaccct atgaatgtaa agaatgtggt aaagccttcc gtatttctag   1920

ttcccttcga agacatgaaa caactcacac tggagagaaa ccctataaat gtaaatgtgg   1980

gaaagccttt attgatttct attcctttca aaatcatgaa acaactcaca ctggagagaa   2040

gccatatgag tgtaaggaat gtgggaaagc attcagttgt ttcacatacc tttctcaaca   2100

tagaaggact cacatggctg aaaaacctta tgaatgtaaa acatgtaaga aagccttcag   2160

tcattttggt aacttaaaag tccatgaaag gattcacact ggagagaagc catatgaatg   2220

taaggaatgc aggaaagcat tctcttggct cacttgcctt ctgcgacatg aaagaattca   2280

cactggaaag aaatcttatg aatgtcaaca atgtggtaaa gccttcactc gttctcgttt   2340

ccttcgagga catgaaaaaa ctcacactgg agagaagatg catgaatgta aggaatgtgg   2400

gaaggcactg agttctctca gttccttgca tagacataaa aggactcact ggagagatac   2460

tctataaatg tggaaaagca ttcattaatt ttatttcatt tcagaaacgt gaaagaaatc   2520

acataggaga taagcctcat gaatgcaaac acatggtaaa gccttaagat gtttcttttg   2580

aatatggtta tcccctaacc atatgcaggg gattggttcc agacccccta agcataccta   2640

aatccacaga tgctgtgttc cttttataaa aggacatttg catgtaacct atccacatcc   2700

tcctgcatcc cataaatcat gcctagatta cttaattttt caccaaccca aagcttttgt   2760

aaaagtaaaa ataaaaagta ggttactaaa atacctc                            2797


<210>  9145
<211>  627
<212>  PRT
<213>  Homo sapiens

<400>  9145

Met Ile Val Phe Gly Gly Glu Asp Arg Ser Asp Leu Phe Leu Pro Asp 
1               5                   10                  15


Ser Gln Thr Asn Glu Glu Arg Lys Gln Tyr Asp Ser Val Ala Phe Glu 
            20                  25                  30


Asp Val Ala Val Asn Phe Thr Gln Glu Glu Trp Ala Leu Leu Gly Pro 
        35                  40                  45


Ser Gln Lys Ser Leu Tyr Arg Asp Val Met Trp Glu Thr Ile Arg Asn 
    50                  55                  60


Leu Asp Cys Ile Gly Met Lys Trp Glu Asp Thr Asn Ile Glu Asp Gln 
65                  70                  75                  80


His Arg Asn Pro Arg Arg Ser Leu Arg Cys His Ile Ile Glu Arg Phe 
                85                  90                  95


Ser Glu Ser Arg Gln Pro Asp Ser Thr Val Asn Glu Lys Pro Pro Gly 
            100                 105                 110


Val Asp Pro Cys Lys Ser Ser Val Cys Gly Glu Ile Met Gly Cys Ser 
        115                 120                 125


Phe Leu Asn Cys Tyr Ile Thr Phe Asp Ala Gly His Lys Pro Asp Glu 
    130                 135                 140


Cys Gln Glu Tyr Gly Glu Lys Pro His Thr His Lys Gln Cys Gly Thr 
145                 150                 155                 160


Ala Phe Asn Tyr His His Ser Phe Gln Thr Gln Glu Arg Pro His Thr 
                165                 170                 175


Gly Lys Lys Arg Tyr Asp Cys Lys Glu Cys Gly Lys Thr Phe Ser Ser 
            180                 185                 190


Ser Gly Asn Leu Arg Arg His Ile Ile Val Gln Arg Gly Gly Gly Pro 
        195                 200                 205


Tyr Ile Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp Pro Ser Leu Phe 
    210                 215                 220


Arg Met His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
225                 230                 235                 240


Gln Cys Cys Lys Ala Phe Pro Ile Tyr Ser Ser Tyr Leu Arg His Glu 
                245                 250                 255


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys His Cys Ser Lys 
            260                 265                 270


Ala Phe Pro Asp Tyr Ser Ser Tyr Val Arg His Glu Arg Thr His Thr 
        275                 280                 285


Gly Glu Lys Pro Tyr Lys Cys Lys Arg Cys Gly Arg Ala Phe Ser Val 
    290                 295                 300


Ser Ser Ser Leu Arg Ile His Glu Arg Thr His Thr Gly Glu Lys Pro 
305                 310                 315                 320


Tyr Glu Cys Lys Gln Cys Gly Lys Ala Phe His His Leu Gly Ser Phe 
                325                 330                 335


Gln Arg His Met Ile Arg His Thr Gly Asp Gly Pro His Lys Cys Lys 
            340                 345                 350


Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu Gln Ser His Glu 
        355                 360                 365


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys 
    370                 375                 380


Ala Leu Ser His His Ser Ser Phe Arg Ser His Met Ile Met His Thr 
385                 390                 395                 400


Gly Asp Gly Pro His Lys Cys Lys Val Cys Gly Lys Ala Phe Ile Tyr 
                405                 410                 415


Pro Ser Val Phe Gln Gly His Glu Arg Thr His Thr Gly Glu Lys Pro 
            420                 425                 430


Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Arg Ile Ser Ser Ser Leu 
        435                 440                 445


Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys 
    450                 455                 460


Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln Asn His Glu Thr 
465                 470                 475                 480


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala 
                485                 490                 495


Phe Ser Cys Phe Thr Tyr Leu Ser Gln His Arg Arg Thr His Met Ala 
            500                 505                 510


Glu Lys Pro Tyr Glu Cys Lys Thr Cys Lys Lys Ala Phe Ser His Phe 
        515                 520                 525


Gly Asn Leu Lys Val His Glu Arg Ile His Thr Gly Glu Lys Pro Tyr 
    530                 535                 540


Glu Cys Lys Glu Cys Arg Lys Ala Phe Ser Trp Leu Thr Cys Leu Leu 
545                 550                 555                 560


Arg His Glu Arg Ile His Thr Gly Lys Lys Ser Tyr Glu Cys Gln Gln 
                565                 570                 575


Cys Gly Lys Ala Phe Thr Arg Ser Arg Phe Leu Arg Gly His Glu Lys 
            580                 585                 590


Thr His Thr Gly Glu Lys Met His Glu Cys Lys Glu Cys Gly Lys Ala 
        595                 600                 605


Leu Ser Ser Leu Ser Ser Leu His Arg His Lys Arg Thr His Trp Arg 
    610                 615                 620


Asp Thr Leu 
625


<210>  9146
<211>  732
<212>  DNA
<213>  Homo sapiens

<400>  9146
cccctctgag ctcccgctcc tggctctgta gctgagagaa gccctggcag gtcagtggca     60

ggcactgtca cgctgagtcc tatgctggca gcggggaacc ttggggagaa cacgggacac    120

cgcggaagcc gggaaatgga atgaaatggg aagacacaaa cattgaagat cagcacagaa    180

atcccaggag gagcctaaga tgtcatatca tagagagatt tagtgaaagt cgccagccag    240

atagtactgt gaatgaaaaa cctcctggag tagatccatg taaaagcagt gtgtgtggag    300

aaatcatggg ttgttcattc cttaattgct atatcacatt tgatgctgga cacaaaccag    360

atgagtgtca ggaatatgga gagaagccac atacacataa acaatgtggg acagccttca    420

attatcacca ctcctttcaa acacaggaaa gacctcacac tggaaagaaa cgctatgatt    480

gtaaggaatg tgggaaaacc ttcagttctt cgggaaacct tcgaagacac ataatagtac    540

aacgtggagg tggaccttat atatgtaagt tgtgtgggaa agcctttttt tggcctagtt    600

tatttcgtat gcatgaaaga actcacactg gagagaaacc gtatgaatgt aagcagtgtt    660

gtaaagcctt ccctatttac agttcctatc taagacatga aagaacacac actggggaga    720

aaccatatga at                                                        732


<210>  9147
<211>  196
<212>  PRT
<213>  Homo sapiens

<400>  9147

Met Lys Trp Glu Asp Thr Asn Ile Glu Asp Gln His Arg Asn Pro Arg 
1               5                   10                  15


Arg Ser Leu Arg Cys His Ile Ile Glu Arg Phe Ser Glu Ser Arg Gln 
            20                  25                  30


Pro Asp Ser Thr Val Asn Glu Lys Pro Pro Gly Val Asp Pro Cys Lys 
        35                  40                  45


Ser Ser Val Cys Gly Glu Ile Met Gly Cys Ser Phe Leu Asn Cys Tyr 
    50                  55                  60


Ile Thr Phe Asp Ala Gly His Lys Pro Asp Glu Cys Gln Glu Tyr Gly 
65                  70                  75                  80


Glu Lys Pro His Thr His Lys Gln Cys Gly Thr Ala Phe Asn Tyr His 
                85                  90                  95


His Ser Phe Gln Thr Gln Glu Arg Pro His Thr Gly Lys Lys Arg Tyr 
            100                 105                 110


Asp Cys Lys Glu Cys Gly Lys Thr Phe Ser Ser Ser Gly Asn Leu Arg 
        115                 120                 125


Arg His Ile Ile Val Gln Arg Gly Gly Gly Pro Tyr Ile Cys Lys Leu 
    130                 135                 140


Cys Gly Lys Ala Phe Phe Trp Pro Ser Leu Phe Arg Met His Glu Arg 
145                 150                 155                 160


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Cys Lys Ala 
                165                 170                 175


Phe Pro Ile Tyr Ser Ser Tyr Leu Arg His Glu Arg Thr His Thr Gly 
            180                 185                 190


Glu Lys Pro Tyr 
        195


<210>  9148
<211>  567
<212>  DNA
<213>  Homo sapiens

<400>  9148
aatgcaaatg tcccctggga ggggtcaggt cacagcgaag ggaggaagcc caccctatca     60

agggctgtgt ctggaaccgc ttcatctcgc tccactcagc cgtgaatgaa atgggaagac    120

acaaacattg aagatcagca cagaaatccc aggaggagcc taagatgtca tatcatagag    180

agatttagtg aaagtcgcca gccagatagt actgtgaatg aaaaacctcc tggagtagat    240

ccatgtaaaa gcagtgtgtg tggagaaatc atgggttgtt cattccttaa ttgctatatc    300

acatttgatg ctggacacaa accagatgag tgtcaggaat atggagagaa gccacataca    360

cataaacaat gtgggacagc cttcaattat caccactcct ttcaaacaca ggaaagacct    420

cacactggaa agaaacgcta tgattgtaag gaatgtggga aaaccttcag ttcttcggga    480

aaccttcgaa gacacataat agtacaacgt ggaggtggac cttatatatg taagttgtgt    540

gggaaagcct ttttttggcc tagttta                                        567


<210>  9149
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  9149

Met Lys Trp Glu Asp Thr Asn Ile Glu Asp Gln His Arg Asn Pro Arg 
1               5                   10                  15


Arg Ser Leu Arg Cys His Ile Ile Glu Arg Phe Ser Glu Ser Arg Gln 
            20                  25                  30


Pro Asp Ser Thr Val Asn Glu Lys Pro Pro Gly Val Asp Pro Cys Lys 
        35                  40                  45


Ser Ser Val Cys Gly Glu Ile Met Gly Cys Ser Phe Leu Asn Cys Tyr 
    50                  55                  60


Ile Thr Phe Asp Ala Gly His Lys Pro Asp Glu Cys Gln Glu Tyr Gly 
65                  70                  75                  80


Glu Lys Pro His Thr His Lys Gln Cys Gly Thr Ala Phe Asn Tyr His 
                85                  90                  95


His Ser Phe Gln Thr Gln Glu Arg Pro His Thr Gly Lys Lys Arg Tyr 
            100                 105                 110


Asp Cys Lys Glu Cys Gly Lys Thr Phe Ser Ser Ser Gly Asn Leu Arg 
        115                 120                 125


Arg His Ile Ile Val Gln Arg Gly Gly Gly Pro Tyr Ile Cys Lys Leu 
    130                 135                 140


Cys Gly Lys Ala Phe Phe Trp Pro Ser 
145                 150


<210>  9150
<211>  476
<212>  DNA
<213>  Homo sapiens

<400>  9150
gtcagtggca ggcactgtca cgctgagtcc tatgctggca gcggggaacc ttggggagaa     60

cacgggacac cgcggaagcc gggaaatgga ttcagtagcc tttgaggatg tggcggtgaa    120

cttcacccag gaagagtggg ctttgctggg tccatcacag aagagtctgt acagagatgt    180

gatgtgggaa accattagga acctggactg tataggaatg aaatgggaag acacaaacat    240

tgaagatcag cacagaaatc ccaggaggag cctaagatgt catatcatag agagatttag    300

tgaaagtcgc cagccagata gtactgtgaa tgaaaaacct cctggagtag atccatgtaa    360

aagcagtgtg tgtggagaaa tcatgggttg ttcattcctt aattgctata tcacatttga    420

tgctggacac aaaccagatg agtgtcagga atatggagag aagccacata cacata        476


<210>  9151
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  9151

Met Leu Ala Ala Gly Asn Leu Gly Glu Asn Thr Gly His Arg Gly Ser 
1               5                   10                  15


Arg Glu Met Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr 
            20                  25                  30


Gln Glu Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Ser Leu Tyr Arg 
        35                  40                  45


Asp Val Met Trp Glu Thr Ile Arg Asn Leu Asp Cys Ile Gly Met Lys 
    50                  55                  60


Trp Glu Asp Thr Asn Ile Glu Asp Gln His Arg Asn Pro Arg Arg Ser 
65                  70                  75                  80


Leu Arg Cys His Ile Ile Glu Arg Phe Ser Glu Ser Arg Gln Pro Asp 
                85                  90                  95


Ser Thr Val Asn Glu Lys Pro Pro Gly Val Asp Pro Cys Lys Ser Ser 
            100                 105                 110


Val Cys Gly Glu Ile Met Gly Cys Ser Phe Leu Asn Cys Tyr Ile Thr 
        115                 120                 125


Phe Asp Ala Gly His Lys Pro Asp Glu Cys Gln Glu Tyr Gly Glu Lys 
    130                 135                 140


Pro His Thr 
145


<210>  9152
<211>  536
<212>  DNA
<213>  Homo sapiens

<400>  9152
gctcccgctc ctggctctgt agctgagaga agccctggca ggtcagtggc aggcactgtc     60

acgctgagtc ctatgctggc agcggggaac cttggggaga acacgggaca ccgcggaagc    120

cgggaaatgg attcagtagc ctttgaggat gtggcggtga acttcaccca ggaagagtgg    180

gctttgctgg gtccatcaca gaagagtctg tacagagatg tgatgtggga aaccattagg    240

aacctggact gtataggaat gaaatgggaa gacacaaaca ttgaagatca gcacagaaat    300

cccaggagga gcctaaggta atttgcactc acaagagaaa gacatatatc tgtggagcaa    360

ttcttaggat gacaggaaat tatacaacta ggcaaagaaa atgaacgagc ccagtacaaa    420

cttatttatt cctatacaat tttctccaga aacatatact taaatgtgat ataactattc    480

agtgtttgca aaaatagttc ccttagaaac aatattaaga attcggctgg gcacgg        536


<210>  9153
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  9153

Met Leu Ala Ala Gly Asn Leu Gly Glu Asn Thr Gly His Arg Gly Ser 
1               5                   10                  15


Arg Glu Met Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr 
            20                  25                  30


Gln Glu Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Ser Leu Tyr Arg 
        35                  40                  45


Asp Val Met Trp Glu Thr Ile Arg Asn Leu Asp Cys Ile Gly Met Lys 
    50                  55                  60


Trp Glu Asp Thr Asn Ile Glu Asp Gln His Arg Asn Pro Arg Arg Ser 
65                  70                  75                  80


Leu Arg 



<210>  9154
<211>  2592
<212>  DNA
<213>  Homo sapiens

<400>  9154
actgtcaatc aggcgcgctt cccagaggag tgtgtggttg aaaaagcccg cggcgtcttc     60

tccacccacc tgcgctgggc gctcggtgct cggctctgta gctaagagac gacctggaag    120

ttccgtggca gcctgtgtcc cgcgggaacc cgcattggca gcgggagccg tccggaggac    180

ctgggacacc gcggaagtcg ggaaatggac tcagttgcct ttgaggatgt ggctgtgaac    240

ttcacccagg aagagtgggc tttgctgggt ccttgccaga agaatctcta cgaagatgtg    300

atgcaggaaa ccatcaggaa cctggactgt gtaggaatga aatgagaaga ccagatcagg    360

gaagatcaat acgaaagtca caggataaat gtaagatgcg atatggtaga gcgcttcggt    420

gaaagtaaag acagtagtca ttgtggagaa acatctagcc agattggaga tactgttgtg    480

aacaagcaca tgcctcctgg agtaggtcca cgtgaaaaca atgagtggag aagtcgtcac    540

gggtctttca tcccttcatt gccacatcag agttgatgct gggcacaaac cacatgagta    600

tcaggaatat ggagagaagc gtaatacacg taaacaattt tggaaaacct tcagttattg    660

ccactcgttt caaacccaca aaatttctca cacaggacac aaaccatatg attgtaagga    720

atgtaggaag tccttcaatt ctttgggaaa ccttcaaaga cacatggcag tgcagcatgg    780

agatggacct tataaatgta agttgtgtgg gaaagcattt ttctggccca gtttatttcg    840

tatgcatgaa agaactcact ctggagagaa actatatgaa tgtaagcagt gttctaaagc    900

ctttcatttt tacagttctt atctaagaca tgaaagaaca cgtactgggg agaaactgta    960

tgaatgtaag cagtgttcta aagccttccc tgattacagt tcttgtctaa gacatgaaaa   1020

aactcacact ggagagaaac tctgtacatg taaacaatgt gggaaagcct tcagtgcttc   1080

cacttccctt caaagacgtg aaaccactca cagtgcagag aaaccccatg aatgtaagca   1140

atgtgggaaa gcatttgatc atctgggaag cttccaaaga cacatgataa ggcacactag   1200

agatggacct cataaatgta agatatgtgg gaaaggcttt gattgttcca gtacactgca   1260

aagtcatgaa agaactcaca ctggagagaa gaaactctat gaatgcaagc agtgtgggaa   1320

agcgttatct catagctcaa gctttcgaag acacatgaca atgcacactg gagatggacc   1380

tcacaaaatg caagatatgt gggaaagcct ttgtttattt cattggattt caaagacatg   1440

aaaggactca cactagggag aaaatctata aatgtaaatg tgggaaagcc tttagtgatc   1500

tttattccct tcaaaatcat gagacaactc atatgggaga gaagccatat gaatgtaaat   1560

aatgtgggaa agcatttggt tgtttccagt acctttctct tcataaaaaa atcatacagc   1620

agaaaaacct tatgagtgtc aaacatgtag aaaagccttc agtcattttg gtcacttaaa   1680

gcaacatgaa aggattcaca ctggagagaa gccgtatgaa tgtaaggaat gcaggaaagc   1740

attctcttgg ctcacttgcc ttctacaaca tgaaagaatt cacactcgag agaaacctta   1800

tgaaggtaaa caatgtggta aagccttcac tcattcccgt ttccttcaag gacatgaaag   1860

aactcatacc gcaaagaagc tatgtgaatg taaggaatgt ggaaaagcat tgagttctct   1920

cagctccttg cacagacaca aaaggactca ttggaaagat actctataaa tgtgtggaat   1980

gtgggaaagc attcattaat tttattttac ctgagaaaat taaacaaatc acattggaaa   2040

taaactctat ggcttgggca cggtggctca tgcctgtaat ccctaacact ttgggaggcc   2100

gaggtgggcg gatcacgagg tcaggagatc aagaccatcc tggccaacat ggtgaaaccc   2160

tgtctctact aaaatacaaa aacttagcca ggcatggtgg tgcgcacctg tagtcccagc   2220

tactctggag gctgaggcag gggaatggct cgaacacagg agacggagat tgcagtgagc   2280

tgagatggcg ccactgcact ccagcctggc aacagagtga gactccatct caaaaaaaat   2340

aaaaaaaaag aaaaagaaat aaactctatg aatgtaaacc atgtggtgaa ggcttaagtg   2400

atttcagttt atttcaaata cagttttccc ctgacatatg caggggatta attccagcag   2460

tccctgatca tacctaaatc cacacatgcc aagtttcttt tataaaatta catatttgca   2520

tgttatctac ccacatctcc ctgtacactc taagtcatct ctggattaaa tacctcatgc   2580

attgtaaaaa ct                                                       2592


<210>  9155
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  9155

Met Asp Ser Val Ala Phe Glu Asp Val Ala Val Asn Phe Thr Gln Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Glu Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys 
        35                  40                  45


<210>  9156
<211>  1475
<212>  DNA
<213>  Homo sapiens

<400>  9156
ttacagttct tatctaagac atgaaagaac acgtactggg gagaaactgt atgaatgtaa     60

gcagtgttct aaagccttcc ctgattacag ttcttgtcta agacatgaaa aaactcacac    120

tggagagaaa ctctcataaa tgtaagatat gtgggaaagg ctttgattgt tccagtacac    180

tgcaaagtca tgaaagaact cacactggag agaagaaact ctatgaatgc aagcagtgtg    240

ggaaagcgtt atctcatagc tcaagctttc gaagacacat gacaatgcac actggagatg    300

gacctcacaa aatgcaagat atgtgggaaa gcctttgttt atttcattgg atttcaaaga    360

catgaaagga ctcacactag ggagaaaatc tataaatgta aatgtgggaa agcctttagt    420

gatctttatt cccttcaaaa tcatgagaca actcatatgg gagagaagcc atatgaatgt    480

aaataatgtg ggaaagcatt tggttgtttc cagtaccttt ctcttcataa aaaaatcata    540

cagcagaaaa accttatgag tgtcaaacat gtagaaaagc cttcagtcat tttggtcact    600

taaagcaaca tgaaaggatt cacactggag agaagccgta tgaatgtaag gaatgcagga    660

aagcattctc ttggctcact tgccttctac aacatgaaag aattcacact cgagagaaac    720

cttatgaagg taaacaatgt ggtaaagcct tcactcattc ccgtttcctt caaggacatg    780

aaagaactca taccgcaaag aagctatgtg aatgtaagga atgtggaaaa gcattgagtt    840

ctctcagctc cttgcacaga cacaaaagga ctcattggaa agatactcta taaatgtgtg    900

gaatgtggga aagcattcat taattttatt ttacctgaga aaattaaaca aatcacattg    960

gaaataaact ctatggcttg ggcacggtgg ctcatgcctg taatccctaa cactttggga   1020

ggccgaggtg ggcggatcac gaggtcagga gatcaagacc atcctggcca acatggtgaa   1080

accctgtctc tactaaaata caaaaactta gccaggcatg gtggtgcgca cctgtagtcc   1140

cagctactct ggaggctgag gcaggggaat ggctcgaaca caggagacgg agattgcagt   1200

gagctgagat ggcgccactg cactccagcc tggcaacaga gtgagactcc atctcaaaaa   1260

aaataaaaaa aaagaaaaag aaataaactc tatgaatgta aaccatgtgg tgaaggctta   1320

agtgatttca gtttatttca aatacagttt tcccctgaca tatgcagggg attaattcca   1380

gcagtccctg atcataccta aatccacaca tgccaagttt cttttataaa attacatatt   1440

tgcatgttat ctacccacat ctccctgtac actct                              1475


<210>  9157
<211>  86
<212>  PRT
<213>  Homo sapiens

<400>  9157

Met Lys Lys Leu Thr Leu Glu Arg Asn Ser His Lys Cys Lys Ile Cys 
1               5                   10                  15


Gly Lys Gly Phe Asp Cys Ser Ser Thr Leu Gln Ser His Glu Arg Thr 
            20                  25                  30


His Thr Gly Glu Lys Lys Leu Tyr Glu Cys Lys Gln Cys Gly Lys Ala 
        35                  40                  45


Leu Ser His Ser Ser Ser Phe Arg Arg His Met Thr Met His Thr Gly 
    50                  55                  60


Asp Gly Pro His Lys Met Gln Asp Met Trp Glu Ser Leu Cys Leu Phe 
65                  70                  75                  80


His Trp Ile Ser Lys Thr 
                85


<210>  9158
<211>  4538
<212>  DNA
<213>  Homo sapiens

<400>  9158
agtccttata cagattggaa aatgcaaggc aataatttgc aaataagatc tgatatgctg     60

tctctagaat tagtgtccag ggttctatac cgggaactca ggctgctgtg ttcaagactg    120

gtattgatag ggggagggat tgggccaagg acaaataaaa gctccacaag acttttctac    180

cagttttcat ttttctttat atatatattt atctctctgt taatagtacg gggtgccaaa    240

taaaatcctt tatttgtttt tggaatgctg cactttcttg gtgagaaggc tttcagcatt    300

ttttagatac tgtgagttct attagatttg gtaatgtaat ttttgttgac tactaaaaga    360

tttgttttag tttcttagta agtattataa atattcatga gagatgacac tgagttcttt    420

ctaagaatat gtgcagtctt tccccttctt tctttcccct ttggcgttac tcaaaatgtt    480

taaaattttt cctttgaggt ggtgtaatat cttttctcag tctgttgtca tacttcagta    540

catttgatct aaaggaaact agttgccagc ttccaaatat tctctgtaag tataatcaca    600

taggatgggc taaatccccc aaataacaag ttgcaacaaa acgtgaaatg ttatctaccc    660

agaaagttca ttatagaccc aatgcccaga gtgtttcttt gtagctgtct tagcctgttt    720

cttgttattc ataacagaat tactgaacct cggtaattta taagaaacag tatttaattt    780

ttacatttct ggaggctggg aagtccaagg ttaaggctgg gcatctggtg agaaccttct    840

tgctggtggg gactctgcag agtccctagg cggcatagag tatcacatgg tgagggagct    900

gagtgtctag ctcagatctc ttactcttct cagaaggaca tgagatagct catttattca    960

ttcacccgtt acggattaat ctattcatga ggtccaaacc cttaggacta catcacctct   1020

taaacctcac tttttttttt ttactgccac tttggagatt aacattcagt gtgcattttg   1080

gaggggacaa ccattcaaac ctagcagtgg ctgatcaggt gcactccctg tgctgagtat   1140

gtaacaaaat tccaaactct cagaaggaag atggggttaa ggaaatactg tatttttttt   1200

gcgtaaacaa tttaggcaca ctccacccct attattagtt acgctcctgg ggccctcccc   1260

taaatacact gtctagatac catgaaaagc ccaactttgt gaaaaagcat ttgtaaggac   1320

acacagtctc agcactgcta atggtaactc ccttttgcac aataagtagt aggactttat   1380

cgtgccaagg actgcagacc cactgtggaa atcaacatta ggggtgatcc aggctatgtg   1440

attcactcac tcagttcgcc aacaagtggc atgtttctat cccactgtta atttaccaaa   1500

catgtttaac tgtagcttca gagttactgt gtaggagaaa gtgagtgtag acagagaata   1560

agagtgggtt taccatgtca ttgaataaaa tggttggaaa ccacagcatc atgtgaaatt   1620

tatgaagtga gtatagattc tcagtactgt gattttcacc cttcctcctc tgtacatgtg   1680

ggatggatca ggcctcagtg gctttagagg atgtggctgt gaacttcacc cgagaagagt   1740

gggctttgct gggtccttgt cagaagaatc tctacaaaga tgtgatgcag gaaaccatca   1800

ggaacctgga ttgtgtagga atgaaatgga aagaccagaa cattgaagat caatatagat   1860

atcccaggaa aaatctaaga tgtcgtatgt tagagagatt tgttgaaagt aaagatggaa   1920

ctcaatgtgg agaaacatct agccagattc aagatagtat tgtgaccaag aacactcttc   1980

ctggagtagg tccatatgaa agccgtatga gtggagaagt catcatgggt cattcatccc   2040

ttaattgtta catcagagtt ggtgctgggc acaaaccata tgagtatcat gaatgtggag   2100

agaagccaga tacgcataaa caacgtggga aagccttcag ttaccacaac tcacttcaaa   2160

cacatgagag gcttcacact ggaaagaaac catataattg taaagaatgt gggaagtcct   2220

tcagttcttt gggaaacctt caaagacaca tggcagtgca gcgtggagat ggaccttata   2280

aatgtaagtt gtgtgggaaa gcgttttttt ggcccagttt attacatatg catgagagaa   2340

cgcacactgg agagaaacca tatgaatgta agcagtgttc taaagccttt tctttttaca   2400

gttcctatct aagacatgaa agaacacata ctggggagaa actgtatgaa tgtaaacagt   2460

gttctaaagc cttccctgat tacagttctt gtctaagaca tgaaagaact cacactggaa   2520

agaaacccta tacatgtaaa caatgtggga aagccttcag tgcttccact tcccttcgaa   2580

gacacgaaac aactcacact gatgagaaac cctatgcatg tcagcaatgt gggaaagcgt   2640

ttcatcatct gggaagcttt caaagacaca tggtaatgca cacgagagat ggacctcata   2700

agtgtaagat atgtggaaaa ggctttgatt gtcctagttc actgaaaagt catgaaagaa   2760

ctcacactgg agagaaactc tatgaatgca agcagtgtgg gaaagcgtta tctcatagct   2820

caagctttcg aagacacatg acaatgcaca ctggagatgg acctcacaaa tgcaagatat   2880

gtgggaaagc ctttgtttat cccagtgtat ttcaaaggca tgaaaagact cacactgcag   2940

agaaacccta taaatgtaaa caatgtggca aagcctaccg tatttccagt tctcttcgaa   3000

ggcatgaaac aactcatact ggagagaaac cctataaatg caaatgtggg aaagccttta   3060

ttgatttcta ttcctttcaa aatcacaaaa caactcatgc tggagagaag ccatatgagt   3120

gtaaggaatg tgggaaagca ttcagttgtt tccaatacct ttctcaacat agaaggactc   3180

acacaggaga gaaaccttat gagtgtaaca catgtaagaa agccttcagt cattttggta   3240

acttaaaagt acatgaaaga attcactctg gagagaagcc gtatgaatgt aaggaatgtg   3300

ggaaagcatt ctcttggctc acttgctttc tacgacatga aagaattcac atgagagaga   3360

aaccctatga gtgtcaacaa tgtggtaaag ccttcactca ttcccgtttt cttcaaggac   3420

atgaaaaaac tcatactgga gagaacccgt atgaatgtaa ggaatgtggg aaagcatttg   3480

cttctctcag ttccttgcat agacataaaa agactcactg gaaaaaaact cacactggag   3540

agaacccgta tggatgtaag gaatgtggga aagcatttgc ttctctcagt tccttgcata   3600

gacataaaaa gactcactag cattctctct aaatgtatgg aatgtgggaa agcatttatt   3660

aattttattt catttcagat acttgtacga aacacattgg agatagaccc tgtgaatgta   3720

agcacttggt aaaaccttaa gtaatttcag tttctttcca gtacagtcat cccttgatac   3780

ctgctgggta ttggttccag cactccgtga gccatgtcca gtccctttta taaaatgaca   3840

tatttgtatg taacttaccc acatcctctt gtatactctc aattatgtct agattactta   3900

aaatacctca tgcattgtaa aagctatgca aatagttgtt ctattgtatt gtttagggac   3960

tcatgataag gaaaagagtc tatgtatttt cagtatagat gcagtaattg tcagcctatc   4020

aacatagtat agtcagccag aacattaaag tttctttgtt tcaactctca catattgctt   4080

ttgtttaatg tgttaacact taccaaaacc ctgggtcttc tctcttgata acccaagtat   4140

agtgattata acgatgatga ttctgtggtg cccagtgttt tgatgtgttg agatgactag   4200

atgtatggca ttgtgggtaa gtagtgagac atcaggttaa cttgaatctt gacaggccat   4260

caggactatc atctatgttg gaagaaccaa cttgtgatta tagatgtgga ctcatttgag   4320

gaggctatgt aatactaatg ttaggatctg tttggcttga gggctgaaga tctgtaacca   4380

ttgaatgttc catcttcttt gcagatgctt agttatagga agctagttct tcttttcctt   4440

tgcttcatta aaaaaaaaat cttgcagtgt ttataggcat gttgttattt ctcgggtgga   4500

gtgaaagctt tgttccattg taggatcttt gaggatcg                           4538


<210>  9159
<211>  645
<212>  PRT
<213>  Homo sapiens

<400>  9159

Met Asp Gln Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr 
1               5                   10                  15


Arg Glu Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys 
            20                  25                  30


Asp Val Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys 
        35                  40                  45


Trp Lys Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn 
    50                  55                  60


Leu Arg Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr 
65                  70                  75                  80


Gln Cys Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys 
                85                  90                  95


Asn Thr Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu 
            100                 105                 110


Val Ile Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala 
        115                 120                 125


Gly His Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr 
    130                 135                 140


His Lys Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr 
145                 150                 155                 160


His Glu Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys 
                165                 170                 175


Gly Lys Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val 
            180                 185                 190


Gln Arg Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe 
        195                 200                 205


Phe Trp Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu 
    210                 215                 220


Lys Pro Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser 
225                 230                 235                 240


Ser Tyr Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu 
                245                 250                 255


Cys Lys Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg 
            260                 265                 270


His Glu Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys 
        275                 280                 285


Gly Lys Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr 
    290                 295                 300


His Thr Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe 
305                 310                 315                 320


His His Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp 
                325                 330                 335


Gly Pro His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser 
            340                 345                 350


Ser Leu Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu 
        355                 360                 365


Cys Lys Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg 
    370                 375                 380


His Met Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys 
385                 390                 395                 400


Gly Lys Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr 
                405                 410                 415


His Thr Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr 
            420                 425                 430


Arg Ile Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu 
        435                 440                 445


Lys Pro Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser 
    450                 455                 460


Phe Gln Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys 
465                 470                 475                 480


Lys Glu Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His 
                485                 490                 495


Arg Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys 
            500                 505                 510


Lys Ala Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His 
        515                 520                 525


Ser Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser 
    530                 535                 540


Trp Leu Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys 
545                 550                 555                 560


Pro Tyr Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe 
                565                 570                 575


Leu Gln Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys 
            580                 585                 590


Lys Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His 
        595                 600                 605


Lys Lys Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly 
    610                 615                 620


Cys Lys Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg 
625                 630                 635                 640


His Lys Lys Thr His 
                645


<210>  9160
<211>  3504
<212>  DNA
<213>  Homo sapiens

<400>  9160
aagggctact ccgggatcta cggacccggg ttcccctggc gtaggtcggc cctcggccgc     60

agggtggggc tgggcatgca gccgggaccc cgggcgtcct gtcccgttcc tgcgcggcga    120

ctgcggcccc ggcgccctct ctgggcagct ccgcgcccgc agcctcgcgt ctcccgagat    180

tgtgcggctg taagcaacac aggttcgcgg cccgactcac tgcaccgaga cgctgagggc    240

tgcagcagaa acagtttaat agccagagag gggaggacac cccagatccg cctccctgag    300

ggatttgggg tctggacggg ggcggctggg tgtagggtcg ttggttggtg gggaagtgag    360

gggtgaatcc tgggacagga ggtgaagaaa ccgcattctg ctgaatgggc tccctcgttg    420

ggacttcaac ctgattggcg ccagcctttg ctgggattca ggatctgaga actccggcga    480

ctcttgagca gttctcagag atcttatccc caggcacaat ggggaagccg gcggtcagcg    540

tctgctgtga cctgactctc agggaggcgg ccccttgagg cagcggggct gagggcacct    600

ggttaatatc taactgcaat ctcgcctcca gcctggctcg cagttcctgt gaacccggcc    660

tcagtggctt tagaggatgt ggctgtgaac ttcacccgag aagagtgggc tttgctgggt    720

ccttgtcaga agaatctcta caaagatgtg atgcaggaaa ccatcaggaa cctggattgt    780

gtaggaatga aatggaaaga ccagaacatt gaagatcaat atagatatcc caggaaaaat    840

ctaagatgtc gtatgttaga gagatttgtt gaaagtaaag atggaactca atgtggagaa    900

acatctagcc agattcaaga tagtattgtg accaagaaca ctcttcctgg agtaggtcca    960

tatgaaagcc gtatgagtgg agaagtcatc atgggtcatt catcccttaa ttgttacatc   1020

agagttggtg ctgggcacaa accatatgag tatcatgaat gtggagagaa gccagatacg   1080

cataaacaac gtgggaaagc cttcagttac cacaactcac ttcaaacaca tgagaggctt   1140

cacactggaa agaaaccata taattgtaaa gaatgtggga agtccttcag ttctttggga   1200

aaccttcaaa gacacatggc agtgcagcgt ggagatggac cttataaatg taagttgtgt   1260

gggaaagcgt ttttttggcc cagtttatta catatgcatg agagaacgca cactggagag   1320

aaaccatatg aatgtaagca gtgttctaaa gccttttctt tttacagttc ctatctaaga   1380

catgaaagaa cacatactgg ggagaaactg tatgaatgta aacagtgttc taaagccttc   1440

cctgattaca gttcttgtct aagacatgaa agaactcaca ctggaaagaa accctataca   1500

tgtaaacaat gtgggaaagc cttcagtgct tccacttccc ttcgaagaca cgaaacaact   1560

cacactgatg agaaacccta tgcatgtcag caatgtggga aagcgtttca tcatctggga   1620

agctttcaaa gacacatggt aatgcacacg agagatggac ctcataagtg taagatatgt   1680

ggaaaaggct ttgattgtcc tagttcactg aaaagtcatg aaagaactca cactggagag   1740

aaactctatg aatgcaagca gtgtgggaaa gcgttatctc atagctcaag ctttcgaaga   1800

cacatgacaa tgcacactgg agatggacct cacaaatgca agatatgtgg gaaagccttt   1860

gtttatccca gtgtatttca aaggcatgaa aagactcaca ctgcagagaa accctataaa   1920

tgtaaacaat gtggcaaagc ctaccgtatt tccagttctc ttcgaaggca tgaaacaact   1980

catactggag agaaacccta taaatgcaaa tgtgggaaag cctttattga tttctattcc   2040

tttcaaaatc acaaaacaac tcatgctgga gagaagccat atgagtgtaa ggaatgtggg   2100

aaagcattca gttgtttcca atacctttct caacatagaa ggactcacac aggagagaaa   2160

ccttatgagt gtaacacatg taagaaagcc ttcagtcatt ttggtaactt aaaagtacat   2220

gaaagaattc actctggaga gaagccgtat gaatgtaagg aatgtgggaa agcattctct   2280

tggctcactt gctttctacg acatgaaaga attcacatga gagagaaacc ctatgagtgt   2340

caacaatgtg gtaaagcctt cactcattcc cgttttcttc aaggacatga aaaaactcat   2400

actggagaga acccgtatga atgtaaggaa tgtgggaaag catttgcttc tctcagttcc   2460

ttgcatagac ataaaaagac tcactggaaa aaaactcaca ctggagagaa cccgtatgga   2520

tgtaaggaat gtgggaaagc atttgcttct ctcagttcct tgcatagaca taaaaagact   2580

cactagcatt ctctctaaat gtatggaatg tgggaaagca tttattaatt ttatttcatt   2640

tcagatactt gtacgaaaca cattggagat agaccctgtg aatgtaagca cttggtaaaa   2700

ccttaagtaa tttcagtttc tttccagtac agtcatccct tgatacctgc tgggtattgg   2760

ttccagcact ccgtgagcca tgtccagtcc cttttataaa atgacatatt tgtatgtaac   2820

ttacccacat cctcttgtat actctcaatt atgtctagat tacttaaaat acctcatgca   2880

ttgtaaaagc tatgcaaata gttgttctat tgtattgttt agggactcat gataaggaaa   2940

agagtctatg tattttcagt atagatgcag taattgtcag cctatcaaca tagtatagtc   3000

agccagaaca ttaaagtttc tttgtttcaa ctctcacata ttgcttttgt ttaatgtgtt   3060

aacacttacc aaaaccctgg gtcttctctc ttgataaccc aagtatagtg attataacga   3120

tgatgattct gtggtgccca gtgttttgat gtgttgagat gactagatgt atggcattgt   3180

gggtaagtag tgagacatca ggttaacttg aatcttgaca ggccatcagg actatcatct   3240

atgttggaag aaccaacttg tgattataga tgtggactca tttgaggagg ctatgtaata   3300

ctaatgttag gatctgtttg gcttgagggc tgaagatctg taaccattga atgttccatc   3360

ttctttgcag atgcttagtt ataggaagct agttcttctt ttcctttgct tcattaaaaa   3420

aaaaatcttg cagtgtttat aggcatgttg ttatttctcg ggtggagtga aagctttgtt   3480

ccattgtagg atctttgagg atcg                                          3504


<210>  9161
<211>  611
<212>  PRT
<213>  Homo sapiens

<400>  9161

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
1               5                   10                  15


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
            20                  25                  30


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
        35                  40                  45


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
    50                  55                  60


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
65                  70                  75                  80


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
                85                  90                  95


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
            100                 105                 110


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
        115                 120                 125


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
    130                 135                 140


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
145                 150                 155                 160


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
                165                 170                 175


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
        195                 200                 205


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
225                 230                 235                 240


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
                245                 250                 255


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
            260                 265                 270


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
        275                 280                 285


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
305                 310                 315                 320


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
    370                 375                 380


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
385                 390                 395                 400


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
                405                 410                 415


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
            420                 425                 430


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
        435                 440                 445


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
    450                 455                 460


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
465                 470                 475                 480


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
                485                 490                 495


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
            500                 505                 510


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
        515                 520                 525


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
    530                 535                 540


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
545                 550                 555                 560


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
                565                 570                 575


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
            580                 585                 590


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
        595                 600                 605


Lys Thr His 
    610


<210>  9162
<211>  3166
<212>  DNA
<213>  Homo sapiens

<400>  9162
aatcaggcgc gcttcccaga ggagtgtgtg gttgaaaaag cccgcggcgt cttctccacc     60

cacctgcgct gggcgctcgg tgctcggctc tgtagctaag agacgacctg gaagttccgt    120

ggcagcctgt gtcccgcggg aacccgcatt ggcagcggga gccgtccgga ggacctggga    180

caccgcggaa gtcgggaaat gcgtctcact ctgttgtcca ggctggagtg cagtggcacg    240

atctcagctc actgcaacct ccgcctcctg cgttcaagcg attctcctgc ctcagcctcc    300

cgagtagctg ggactacagg cctcagtggc tttagaggat gtggctgtga acttcacccg    360

agaagagtgg gctttgctgg gtccttgtca gaagaatctc tacaaagatg tgatgcagga    420

aaccatcagg aacctggatt gtgtaggaat gaaatggaaa gaccagaaca ttgaagatca    480

atatagatat cccaggaaaa atctaagatg tcgtatgtta gagagatttg ttgaaagtaa    540

agatggaact caatgtggag aaacatctag ccagattcaa gatagtattg tgaccaagaa    600

cactcttcct ggagtaggtc catatgaaag ccgtatgagt ggagaagtca tcatgggtca    660

ttcatccctt aattgttaca tcagagttgg tgctgggcac aaaccatatg agtatcatga    720

atgtggagag aagccagata cgcataaaca acgtgggaaa gccttcagtt accacaactc    780

acttcaaaca catgagaggc ttcacactgg aaagaaacca tataattgta aagaatgtgg    840

gaagtccttc agttctttgg gaaaccttca aagacacatg gcagtgcagc gtggagatgg    900

accttataaa tgtaagttgt gtgggaaagc gtttttttgg cccagtttat tacatatgca    960

tgagagaacg cacactggag agaaaccata tgaatgtaag cagtgttcta aagccttttc   1020

tttttacagt tcctatctaa gacatgaaag aacacatact ggggagaaac tgtatgaatg   1080

taaacagtgt tctaaagcct tccctgatta cagttcttgt ctaagacatg aaagaactca   1140

cactggaaag aaaccctata catgtaaaca atgtgggaaa gccttcagtg cttccacttc   1200

ccttcgaaga cacgaaacaa ctcacactga tgagaaaccc tatgcatgtc agcaatgtgg   1260

gaaagcgttt catcatctgg gaagctttca aagacacatg gtaatgcaca cgagagatgg   1320

acctcataag tgtaagatat gtggaaaagg ctttgattgt cctagttcac tgaaaagtca   1380

tgaaagaact cacactggag agaaactcta tgaatgcaag cagtgtggga aagcgttatc   1440

tcatagctca agctttcgaa gacacatgac aatgcacact ggagatggac ctcacaaatg   1500

caagatatgt gggaaagcct ttgtttatcc cagtgtattt caaaggcatg aaaagactca   1560

cactgcagag aaaccctata aatgtaaaca atgtggcaaa gcctaccgta tttccagttc   1620

tcttcgaagg catgaaacaa ctcatactgg agagaaaccc tataaatgca aatgtgggaa   1680

agcctttatt gatttctatt cctttcaaaa tcacaaaaca actcatgctg gagagaagcc   1740

atatgagtgt aaggaatgtg ggaaagcatt cagttgtttc caataccttt ctcaacatag   1800

aaggactcac acaggagaga aaccttatga gtgtaacaca tgtaagaaag ccttcagtca   1860

ttttggtaac ttaaaagtac atgaaagaat tcactctgga gagaagccgt atgaatgtaa   1920

ggaatgtggg aaagcattct cttggctcac ttgctttcta cgacatgaaa gaattcacat   1980

gagagagaaa ccctatgagt gtcaacaatg tggtaaagcc ttcactcatt cccgttttct   2040

tcaaggacat gaaaaaactc atactggaga gaacccgtat gaatgtaagg aatgtgggaa   2100

agcatttgct tctctcagtt ccttgcatag acataaaaag actcactgga aaaaaactca   2160

cactggagag aacccgtatg gatgtaagga atgtgggaaa gcatttgctt ctctcagttc   2220

cttgcataga cataaaaaga ctcactagca ttctctctaa atgtatggaa tgtgggaaag   2280

catttattaa ttttatttca tttcagatac ttgtacgaaa cacattggag atagaccctg   2340

tgaatgtaag cacttggtaa aaccttaagt aatttcagtt tctttccagt acagtcatcc   2400

cttgatacct gctgggtatt ggttccagca ctccgtgagc catgtccagt cccttttata   2460

aaatgacata tttgtatgta acttacccac atcctcttgt atactctcaa ttatgtctag   2520

attacttaaa atacctcatg cattgtaaaa gctatgcaaa tagttgttct attgtattgt   2580

ttagggactc atgataagga aaagagtcta tgtattttca gtatagatgc agtaattgtc   2640

agcctatcaa catagtatag tcagccagaa cattaaagtt tctttgtttc aactctcaca   2700

tattgctttt gtttaatgtg ttaacactta ccaaaaccct gggtcttctc tcttgataac   2760

ccaagtatag tgattataac gatgatgatt ctgtggtgcc cagtgttttg atgtgttgag   2820

atgactagat gtatggcatt gtgggtaagt agtgagacat caggttaact tgaatcttga   2880

caggccatca ggactatcat ctatgttgga agaaccaact tgtgattata gatgtggact   2940

catttgagga ggctatgtaa tactaatgtt aggatctgtt tggcttgagg gctgaagatc   3000

tgtaaccatt gaatgttcca tcttctttgc agatgcttag ttataggaag ctagttcttc   3060

ttttcctttg cttcattaaa aaaaaaatct tgcagtgttt ataggcatgt tgttatttct   3120

cgggtggagt gaaagctttg ttccattgta ggatctttga ggatcg                  3166


<210>  9163
<211>  611
<212>  PRT
<213>  Homo sapiens

<400>  9163

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
1               5                   10                  15


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
            20                  25                  30


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
        35                  40                  45


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
    50                  55                  60


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
65                  70                  75                  80


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
                85                  90                  95


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
            100                 105                 110


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
        115                 120                 125


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
    130                 135                 140


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
145                 150                 155                 160


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
                165                 170                 175


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
        195                 200                 205


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
225                 230                 235                 240


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
                245                 250                 255


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
            260                 265                 270


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
        275                 280                 285


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
305                 310                 315                 320


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
    370                 375                 380


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
385                 390                 395                 400


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
                405                 410                 415


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
            420                 425                 430


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
        435                 440                 445


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
    450                 455                 460


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
465                 470                 475                 480


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
                485                 490                 495


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
            500                 505                 510


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
        515                 520                 525


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
    530                 535                 540


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
545                 550                 555                 560


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
                565                 570                 575


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
            580                 585                 590


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
        595                 600                 605


Lys Thr His 
    610


<210>  9164
<211>  3051
<212>  DNA
<213>  Homo sapiens

<400>  9164
gtcaatcagg cgcgcttccc agaggagtgt gtggttgaaa aagcccgcgg cgtcttctcc     60

acccacctgc gctgggcgct cggtgctcgg ctctgtagct aagagacgac ctggaagttc    120

cgtggcagcc tgtgtcccgc gggaacccgc attggcagcg ggagccgtcc ggaggacctg    180

ggacaccgcg gaagtcggga aatggcctca gtggctttag aggatgtggc tgtgaacttc    240

acccgagaag agtgggcttt gctgggtcct tgtcagaaga atctctacaa agatgtgatg    300

caggaaacca tcaggaacct ggattgtgta ggaatgaaat ggaaagacca gaacattgaa    360

gatcaatata gatatcccag gaaaaatcta agatgtcgta tgttagagag atttgttgaa    420

agtaaagatg gaactcaatg tggagaaaca tctagccaga ttcaagatag tattgtgacc    480

aagaacactc ttcctggagt aggtccatat gaaagccgta tgagtggaga agtcatcatg    540

ggtcattcat cccttaattg ttacatcaga gttggtgctg ggcacaaacc atatgagtat    600

catgaatgtg gagagaagcc agatacgcat aaacaacgtg ggaaagcctt cagttaccac    660

aactcacttc aaacacatga gaggcttcac actggaaaga aaccatataa ttgtaaagaa    720

tgtgggaagt ccttcagttc tttgggaaac cttcaaagac acatggcagt gcagcgtgga    780

gatggacctt ataaatgtaa gttgtgtggg aaagcgtttt tttggcccag tttattacat    840

atgcatgaga gaacgcacac tggagagaaa ccatatgaat gtaagcagtg ttctaaagcc    900

ttttcttttt acagttccta tctaagacat gaaagaacac atactgggga gaaactgtat    960

gaatgtaaac agtgttctaa agccttccct gattacagtt cttgtctaag acatgaaaga   1020

actcacactg gaaagaaacc ctatacatgt aaacaatgtg ggaaagcctt cagtgcttcc   1080

acttcccttc gaagacacga aacaactcac actgatgaga aaccctatgc atgtcagcaa   1140

tgtgggaaag cgtttcatca tctgggaagc tttcaaagac acatggtaat gcacacgaga   1200

gatggacctc ataagtgtaa gatatgtgga aaaggctttg attgtcctag ttcactgaaa   1260

agtcatgaaa gaactcacac tggagagaaa ctctatgaat gcaagcagtg tgggaaagcg   1320

ttatctcata gctcaagctt tcgaagacac atgacaatgc acactggaga tggacctcac   1380

aaatgcaaga tatgtgggaa agcctttgtt tatcccagtg tatttcaaag gcatgaaaag   1440

actcacactg cagagaaacc ctataaatgt aaacaatgtg gcaaagccta ccgtatttcc   1500

agttctcttc gaaggcatga aacaactcat actggagaga aaccctataa atgcaaatgt   1560

gggaaagcct ttattgattt ctattccttt caaaatcaca aaacaactca tgctggagag   1620

aagccatatg agtgtaagga atgtgggaaa gcattcagtt gtttccaata cctttctcaa   1680

catagaagga ctcacacagg agagaaacct tatgagtgta acacatgtaa gaaagccttc   1740

agtcattttg gtaacttaaa agtacatgaa agaattcact ctggagagaa gccgtatgaa   1800

tgtaaggaat gtgggaaagc attctcttgg ctcacttgct ttctacgaca tgaaagaatt   1860

cacatgagag agaaacccta tgagtgtcaa caatgtggta aagccttcac tcattcccgt   1920

tttcttcaag gacatgaaaa aactcatact ggagagaacc cgtatgaatg taaggaatgt   1980

gggaaagcat ttgcttctct cagttccttg catagacata aaaagactca ctggaaaaaa   2040

actcacactg gagagaaccc gtatggatgt aaggaatgtg ggaaagcatt tgcttctctc   2100

agttccttgc atagacataa aaagactcac tagcattctc tctaaatgta tggaatgtgg   2160

gaaagcattt attaatttta tttcatttca gatacttgta cgaaacacat tggagataga   2220

ccctgtgaat gtaagcactt ggtaaaacct taagtaattt cagtttcttt ccagtacagt   2280

catcccttga tacctgctgg gtattggttc cagcactccg tgagccatgt ccagtccctt   2340

ttataaaatg acatatttgt atgtaactta cccacatcct cttgtatact ctcaattatg   2400

tctagattac ttaaaatacc tcatgcattg taaaagctat gcaaatagtt gttctattgt   2460

attgtttagg gactcatgat aaggaaaaga gtctatgtat tttcagtata gatgcagtaa   2520

ttgtcagcct atcaacatag tatagtcagc cagaacatta aagtttcttt gtttcaactc   2580

tcacatattg cttttgttta atgtgttaac acttaccaaa accctgggtc ttctctcttg   2640

ataacccaag tatagtgatt ataacgatga tgattctgtg gtgcccagtg ttttgatgtg   2700

ttgagatgac tagatgtatg gcattgtggg taagtagtga gacatcaggt taacttgaat   2760

cttgacaggc catcaggact atcatctatg ttggaagaac caacttgtga ttatagatgt   2820

ggactcattt gaggaggcta tgtaatacta atgttaggat ctgtttggct tgagggctga   2880

agatctgtaa ccattgaatg ttccatcttc tttgcagatg cttagttata ggaagctagt   2940

tcttcttttc ctttgcttca ttaaaaaaaa aatcttgcag tgtttatagg catgttgtta   3000

tttctcgggt ggagtgaaag ctttgttcca ttgtaggatc tttgaggatc g            3051


<210>  9165
<211>  643
<212>  PRT
<213>  Homo sapiens

<400>  9165

Met Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr Arg Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
        35                  40                  45


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
    50                  55                  60


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
65                  70                  75                  80


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
                85                  90                  95


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
            100                 105                 110


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
        115                 120                 125


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
145                 150                 155                 160


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
225                 230                 235                 240


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
            260                 265                 270


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
    290                 295                 300


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
305                 310                 315                 320


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
                325                 330                 335


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
            340                 345                 350


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
        355                 360                 365


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
    370                 375                 380


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
385                 390                 395                 400


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
                405                 410                 415


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
            420                 425                 430


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
        435                 440                 445


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
    450                 455                 460


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
465                 470                 475                 480


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
                485                 490                 495


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
            500                 505                 510


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
        515                 520                 525


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
    530                 535                 540


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
545                 550                 555                 560


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
                565                 570                 575


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
            580                 585                 590


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
        595                 600                 605


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
    610                 615                 620


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
625                 630                 635                 640


Lys Thr His 



<210>  9166
<211>  4075
<212>  DNA
<213>  Homo sapiens

<400>  9166
cgggatagtc cttatacaga ttggaaaatg caaggcaata atttgcaaat aagatctgat     60

atgctgtctc tagaattagt gtccagggtt ctataccggg aactcaggct gctgtgttca    120

agactggtat tgataggggg agggattggg ccaaggacaa ataaaagctc cacaagactt    180

ttctaccagt tttcattttt ctttatatat atatttatct ctctgttaat agtacggggt    240

gccaaataaa atcctttatt tgtttttgga atgctgcact ttcttggtga gaaggctttc    300

agcatttttt agatactgtg agttctatta gatttggtaa tgtaattttt gttgactact    360

aaaagatttg ttttagtttc ttagtaagta ttataaatat tcatgagaga tgacactgag    420

ttctttctaa gaatatgtgc agtctttccc cttctttctt tcccctttgg cgttactcaa    480

aatgtttaaa atttttcctt tgaggtggtg taatatcttt tctcagtctg ttgtcatact    540

tcagtacatt tgatctaaag gaaactagtt gccagcttcc aaatattctc tgtaagtata    600

atcacatagg atgggctaaa tcccccaaat aacaagttgc aacaaaacgt gaaatgttat    660

ctacccagaa agttcattat agacccaatg cccagagtgt ttctttgtag ctgtcttagc    720

ctgtttcttg ttattcataa cagaattact gaacctcggt aatttataag aaacagtatt    780

taatttttac atttctggag gctgggaagt ccaaggttaa ggctgggcat ctggtgagaa    840

ccttcttgct ggtggggact ctgcagagtc cctaggcggc atagagtatc acatggtgag    900

ggagctgagt gtctagctca gatctcttac tcttctcaga aggacatgag atagctcatt    960

tattcattca cccgttacgg attaatctat tcatgaggtc caaaccctta ggactacatc   1020

acctcttaaa cctcactttt ttttttttac tgccactttg gagattaaca ttcagtgtgc   1080

attttggagg ggacaaccat tcaaacctag cagtggctga tcaggtgcac tccctgtgct   1140

gagtatgtaa caaaattcca aactctcaga aggaagatgg ggttaaggaa atactgtatt   1200

ttttttgcgt aaacaattta ggcacactcc acccctatta ttagttacgc tcctggggcc   1260

ctcccctaaa tacactgtct agataccatg aaaagcccaa ctttgtgaaa aagcatttgt   1320

aaggacacac agtctcagca ctgctaatgg taactccctt ttgcacaata agtagtagga   1380

ctttatcgtg ccaaggactg cagacccact gtggaaatca acattagggg tgatccaggc   1440

tatgtgattc actcactcag ttcgccaaca agtggcatgt ttctatccca ctgttaattt   1500

accaaacatg tttaactgta gcttcagagt tactgtgtag gagaaagtga gtgtagacag   1560

agaataagag tgggtttacc atgtcattga ataaaatggt tggaaaccac agcatcatgt   1620

gaaatttatg aagtgagtat agattctcag tactgtgatt ttcacccttc ctcctctgta   1680

catgtgggat ggatcaggcc tcagtggctt tagaggatgt ggctgtgaac ttcacccgag   1740

aagagtgggc tttgctgggt ccttgtcaga agaatctcta caaagatgtg atgcaggaaa   1800

ccatcaggaa cctggattgt gtaggaatga aatggaaaga ccagaacatt gaagatcaat   1860

atagatatcc caggaaaaat ctaagatgtc gtatgttaga gagatttgtt gaaagtaaag   1920

atggaactca atgtggagaa acatctagcc agattcaaga tagtattgtg accaagaaca   1980

ctcttcctgg agtaggtcca tatgaaagcc gtatgagtgg agaagtcatc atgggtcatt   2040

catcccttaa ttgttacatc agagttggtg ctgggcacaa accatatgag tatcatgaat   2100

gtggagagaa gccagatacg cataaacaac gtgggaaagc cttcagttac cacaactcac   2160

ttcaaacaca tgagaggctt cacactggaa agaaaccata taattgtaaa gaatgtggga   2220

agtccttcag ttctttggga aaccttcaaa gacacatggc agtgcagcgt ggagatggac   2280

cttataaatg taagttgtgt gggaaagcgt ttttttggcc cagtttatta catatgcatg   2340

agagaacgca cactggagag aaaccatatg aatgtaagca gtgttctaaa gccttttctt   2400

tttacagttc ctatctaaga catgaaagaa cacatactgg ggagaaactg tatgaatgta   2460

aacagtgttc taaagccttc cctgattaca gttcttgtct aagacatgaa agaactcaca   2520

ctggaaagaa accctataca tgtaaacaat gtgggaaagc cttcagtgct tccacttccc   2580

ttcgaagaca cgaaacaact cacactgatg agaaacccta tgcatgtcag caatgtggga   2640

aagcgtttca tcatctggga agctttcaaa gacacatggt aatgcacacg agagatggac   2700

ctcataagtg taagatatgt ggaaaaggct ttgattgtcc tagttcactg aaaagtcatg   2760

aaagaactca cactggagag aaactctatg aatgcaagca gtgtgggaaa gcgttatctc   2820

atagctcaag ctttcgaaga cacatgacaa tgcacactgg agatggacct cacaaatgca   2880

agatatgtgg gaaagccttt gtttatccca gtgtatttca aaggcatgaa aagactcaca   2940

ctgcagagaa accctataaa tgtaaacaat gtggcaaagc ctaccgtatt tccagttctc   3000

ttcgaaggca tgaaacaact catactggag agaaacccta taaatgcaaa tgtgggaaag   3060

cctttattga tttctattcc tttcaaaatc acaaaacaac tcatgctgga gagaagccat   3120

atgagtgtaa ggaatgtggg aaagcattca gttgtttcca atacctttct caacatagaa   3180

ggactcacac aggagagaaa ccttatgagt gtaacacatg taagaaagcc ttcagtcatt   3240

ttggtaactt aaaagtacat gaaagaattc actctggaga gaagccgtat gaatgtaagg   3300

aatgtgggaa agcattctct tggctcactt gctttctacg acatgaaaga attcacatga   3360

gagagaaacc ctatgagtgt caacaatgtg gtaaagcctt cactcattcc cgttttcttc   3420

aaggacatga aaaaactcat actggagaga acccgtatga atgtaaggaa tgtgggaaag   3480

catttgcttc tctcagttcc ttgcatagac ataaaaagac tcactggaaa aaaactcaca   3540

ctggagagaa cccgtatgga tgtaaggaat gtgggaaagc atttgcttct ctcagttcct   3600

tgcatagaca taaaaagact cactagcatt ctctctaaat gtatggaatg tgggaaagca   3660

tttattaatt ttatttcatt tcagatactt gtacgaaaca cattggagat agaccctgtg   3720

aatgtaagca cttggtaaaa ccttaagtaa tttcagtttc tttccagtac agtcatccct   3780

tgatacctgc tgggtattgg ttccagcact ccgtgagcca tgtccagtcc cttttataaa   3840

atgacatatt tgtatgtaac ttacccacat cctcttgtat actctcaatt atgtctagat   3900

tacttaaaat acctcatgca ttgtaaaagc tatgcaaata gttgttctat tgtattgttt   3960

agggactcat gataaggaaa agagtctatg tattttcagt atagatgcag taattgtcag   4020

cctatcaaca tagtatagtc agccagaaca ttaaagtttc tttgtttcaa ctctc        4075


<210>  9167
<211>  645
<212>  PRT
<213>  Homo sapiens

<400>  9167

Met Asp Gln Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr 
1               5                   10                  15


Arg Glu Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys 
            20                  25                  30


Asp Val Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys 
        35                  40                  45


Trp Lys Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn 
    50                  55                  60


Leu Arg Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr 
65                  70                  75                  80


Gln Cys Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys 
                85                  90                  95


Asn Thr Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu 
            100                 105                 110


Val Ile Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala 
        115                 120                 125


Gly His Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr 
    130                 135                 140


His Lys Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr 
145                 150                 155                 160


His Glu Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys 
                165                 170                 175


Gly Lys Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val 
            180                 185                 190


Gln Arg Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe 
        195                 200                 205


Phe Trp Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu 
    210                 215                 220


Lys Pro Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser 
225                 230                 235                 240


Ser Tyr Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu 
                245                 250                 255


Cys Lys Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg 
            260                 265                 270


His Glu Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys 
        275                 280                 285


Gly Lys Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr 
    290                 295                 300


His Thr Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe 
305                 310                 315                 320


His His Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp 
                325                 330                 335


Gly Pro His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser 
            340                 345                 350


Ser Leu Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu 
        355                 360                 365


Cys Lys Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg 
    370                 375                 380


His Met Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys 
385                 390                 395                 400


Gly Lys Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr 
                405                 410                 415


His Thr Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr 
            420                 425                 430


Arg Ile Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu 
        435                 440                 445


Lys Pro Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser 
    450                 455                 460


Phe Gln Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys 
465                 470                 475                 480


Lys Glu Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His 
                485                 490                 495


Arg Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys 
            500                 505                 510


Lys Ala Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His 
        515                 520                 525


Ser Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser 
    530                 535                 540


Trp Leu Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys 
545                 550                 555                 560


Pro Tyr Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe 
                565                 570                 575


Leu Gln Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys 
            580                 585                 590


Lys Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His 
        595                 600                 605


Lys Lys Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly 
    610                 615                 620


Cys Lys Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg 
625                 630                 635                 640


His Lys Lys Thr His 
                645


<210>  9168
<211>  3035
<212>  DNA
<213>  Homo sapiens

<400>  9168
aagggctact ccgggatcta cggacccggg ttcccctggc gtaggtcggc cctcggccgc     60

agggtggggc tgggcatgca gccgggaccc cgggcgtcct gtcccgttcc tgcgcggcga    120

ctgcggcccc ggcgccctct ctgggcagct ccgcgcccgc agcctcgcgt ctcccgagat    180

tgtgcggctg taagcaacac aggttcgcgg cccgactcac tgcaccgaga cgctgagggc    240

tgcagcagaa acagtttaat agccagagag gggaggacac cccagatccg cctccctgag    300

ggatttgggg tctggacggg ggcggctggg tgtagggtcg ttggttggtg gggaagtgag    360

gggtgaatcc tgggacagga ggtgaagaaa ccgcattctg ctgaatgggc tccctcgttg    420

ggacttcaac ctgattggcg ccagcctttg ctgggattca ggatctgaga actccggcga    480

ctcttgagca gttctcagag atcttatccc caggcacaat ggggaagccg gcggtcagcg    540

tctgctgtga cctgactctc agggaggcgg ccccttgagg cagcggggct gagggcacct    600

ggttaatatc taactgcaat ctcgcctcca gcctggctcg cagttcctgt gaacccggcc    660

tcagtggctt tagaggatgt ggctgtgaac ttcacccgag aagagtgggc tttgctgggt    720

ccttgtcaga agaatctcta caaagatgtg atgcaggaaa ccatcaggaa cctggattgt    780

gtaggaatga aatggaaaga ccagaacatt gaagatcaat atagatatcc caggaaaaat    840

ctaagatgtc gtatgttaga gagatttgtt gaaagtaaag atggaactca atgtggagaa    900

acatctagcc agattcaaga tagtattgtg accaagaaca ctcttcctgg agtaggtcca    960

tatgaaagcc gtatgagtgg agaagtcatc atgggtcatt catcccttaa ttgttacatc   1020

agagttggtg ctgggcacaa accatatgag tatcatgaat gtggagagaa gccagatacg   1080

cataaacaac gtgggaaagc cttcagttac cacaactcac ttcaaacaca tgagaggctt   1140

cacactggaa agaaaccata taattgtaaa gaatgtggga agtccttcag ttctttggga   1200

aaccttcaaa gacacatggc agtgcagcgt ggagatggac cttataaatg taagttgtgt   1260

gggaaagcgt ttttttggcc cagtttatta catatgcatg agagaacgca cactggagag   1320

aaaccatatg aatgtaagca gtgttctaaa gccttttctt tttacagttc ctatctaaga   1380

catgaaagaa cacatactgg ggagaaactg tatgaatgta aacagtgttc taaagccttc   1440

cctgattaca gttcttgtct aagacatgaa agaactcaca ctggaaagaa accctataca   1500

tgtaaacaat gtgggaaagc cttcagtgct tccacttccc ttcgaagaca cgaaacaact   1560

cacactgatg agaaacccta tgcatgtcag caatgtggga aagcgtttca tcatctggga   1620

agctttcaaa gacacatggt aatgcacacg agagatggac ctcataagtg taagatatgt   1680

ggaaaaggct ttgattgtcc tagttcactg aaaagtcatg aaagaactca cactggagag   1740

aaactctatg aatgcaagca gtgtgggaaa gcgttatctc atagctcaag ctttcgaaga   1800

cacatgacaa tgcacactgg agatggacct cacaaatgca agatatgtgg gaaagccttt   1860

gtttatccca gtgtatttca aaggcatgaa aagactcaca ctgcagagaa accctataaa   1920

tgtaaacaat gtggcaaagc ctaccgtatt tccagttctc ttcgaaggca tgaaacaact   1980

catactggag agaaacccta taaatgcaaa tgtgggaaag cctttattga tttctattcc   2040

tttcaaaatc acaaaacaac tcatgctgga gagaagccat atgagtgtaa ggaatgtggg   2100

aaagcattca gttgtttcca atacctttct caacatagaa ggactcacac aggagagaaa   2160

ccttatgagt gtaacacatg taagaaagcc ttcagtcatt ttggtaactt aaaagtacat   2220

gaaagaattc actctggaga gaagccgtat gaatgtaagg aatgtgggaa agcattctct   2280

tggctcactt gctttctacg acatgaaaga attcacatga gagagaaacc ctatgagtgt   2340

caacaatgtg gtaaagcctt cactcattcc cgttttcttc aaggacatga aaaaactcat   2400

actggagaga acccgtatga atgtaaggaa tgtgggaaag catttgcttc tctcagttcc   2460

ttgcatagac ataaaaagac tcactggaaa aaaactcaca ctggagagaa cccgtatgga   2520

tgtaaggaat gtgggaaagc atttgcttct ctcagttcct tgcatagaca taaaaagact   2580

cactagcatt ctctctaaat gtatggaatg tgggaaagca tttattaatt ttatttcatt   2640

tcagatactt gtacgaaaca cattggagat agaccctgtg aatgtaagca cttggtaaaa   2700

ccttaagtaa tttcagtttc tttccagtac agtcatccct tgatacctgc tgggtattgg   2760

ttccagcact ccgtgagcca tgtccagtcc cttttataaa atgacatatt tgtatgtaac   2820

ttacccacat cctcttgtat actctcaatt atgtctagat tacttaaaat acctcatgca   2880

ttgtaaaagc tatgcaaata gttgttctat tgtattgttt agggactcat gataaggaaa   2940

agagtctatg tattttcagt atagatgcag taattgtcag cctatcaaca tagtatagtc   3000

agccagaaca ttaaagtttc tttgtttcaa ctctc                              3035


<210>  9169
<211>  611
<212>  PRT
<213>  Homo sapiens

<400>  9169

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
1               5                   10                  15


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
            20                  25                  30


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
        35                  40                  45


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
    50                  55                  60


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
65                  70                  75                  80


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
                85                  90                  95


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
            100                 105                 110


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
        115                 120                 125


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
    130                 135                 140


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
145                 150                 155                 160


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
                165                 170                 175


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
        195                 200                 205


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
225                 230                 235                 240


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
                245                 250                 255


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
            260                 265                 270


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
        275                 280                 285


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
305                 310                 315                 320


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
    370                 375                 380


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
385                 390                 395                 400


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
                405                 410                 415


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
            420                 425                 430


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
        435                 440                 445


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
    450                 455                 460


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
465                 470                 475                 480


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
                485                 490                 495


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
            500                 505                 510


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
        515                 520                 525


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
    530                 535                 540


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
545                 550                 555                 560


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
                565                 570                 575


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
            580                 585                 590


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
        595                 600                 605


Lys Thr His 
    610


<210>  9170
<211>  2697
<212>  DNA
<213>  Homo sapiens

<400>  9170
aatcaggcgc gcttcccaga ggagtgtgtg gttgaaaaag cccgcggcgt cttctccacc     60

cacctgcgct gggcgctcgg tgctcggctc tgtagctaag agacgacctg gaagttccgt    120

ggcagcctgt gtcccgcggg aacccgcatt ggcagcggga gccgtccgga ggacctggga    180

caccgcggaa gtcgggaaat gcgtctcact ctgttgtcca ggctggagtg cagtggcacg    240

atctcagctc actgcaacct ccgcctcctg cgttcaagcg attctcctgc ctcagcctcc    300

cgagtagctg ggactacagg cctcagtggc tttagaggat gtggctgtga acttcacccg    360

agaagagtgg gctttgctgg gtccttgtca gaagaatctc tacaaagatg tgatgcagga    420

aaccatcagg aacctggatt gtgtaggaat gaaatggaaa gaccagaaca ttgaagatca    480

atatagatat cccaggaaaa atctaagatg tcgtatgtta gagagatttg ttgaaagtaa    540

agatggaact caatgtggag aaacatctag ccagattcaa gatagtattg tgaccaagaa    600

cactcttcct ggagtaggtc catatgaaag ccgtatgagt ggagaagtca tcatgggtca    660

ttcatccctt aattgttaca tcagagttgg tgctgggcac aaaccatatg agtatcatga    720

atgtggagag aagccagata cgcataaaca acgtgggaaa gccttcagtt accacaactc    780

acttcaaaca catgagaggc ttcacactgg aaagaaacca tataattgta aagaatgtgg    840

gaagtccttc agttctttgg gaaaccttca aagacacatg gcagtgcagc gtggagatgg    900

accttataaa tgtaagttgt gtgggaaagc gtttttttgg cccagtttat tacatatgca    960

tgagagaacg cacactggag agaaaccata tgaatgtaag cagtgttcta aagccttttc   1020

tttttacagt tcctatctaa gacatgaaag aacacatact ggggagaaac tgtatgaatg   1080

taaacagtgt tctaaagcct tccctgatta cagttcttgt ctaagacatg aaagaactca   1140

cactggaaag aaaccctata catgtaaaca atgtgggaaa gccttcagtg cttccacttc   1200

ccttcgaaga cacgaaacaa ctcacactga tgagaaaccc tatgcatgtc agcaatgtgg   1260

gaaagcgttt catcatctgg gaagctttca aagacacatg gtaatgcaca cgagagatgg   1320

acctcataag tgtaagatat gtggaaaagg ctttgattgt cctagttcac tgaaaagtca   1380

tgaaagaact cacactggag agaaactcta tgaatgcaag cagtgtggga aagcgttatc   1440

tcatagctca agctttcgaa gacacatgac aatgcacact ggagatggac ctcacaaatg   1500

caagatatgt gggaaagcct ttgtttatcc cagtgtattt caaaggcatg aaaagactca   1560

cactgcagag aaaccctata aatgtaaaca atgtggcaaa gcctaccgta tttccagttc   1620

tcttcgaagg catgaaacaa ctcatactgg agagaaaccc tataaatgca aatgtgggaa   1680

agcctttatt gatttctatt cctttcaaaa tcacaaaaca actcatgctg gagagaagcc   1740

atatgagtgt aaggaatgtg ggaaagcatt cagttgtttc caataccttt ctcaacatag   1800

aaggactcac acaggagaga aaccttatga gtgtaacaca tgtaagaaag ccttcagtca   1860

ttttggtaac ttaaaagtac atgaaagaat tcactctgga gagaagccgt atgaatgtaa   1920

ggaatgtggg aaagcattct cttggctcac ttgctttcta cgacatgaaa gaattcacat   1980

gagagagaaa ccctatgagt gtcaacaatg tggtaaagcc ttcactcatt cccgttttct   2040

tcaaggacat gaaaaaactc atactggaga gaacccgtat gaatgtaagg aatgtgggaa   2100

agcatttgct tctctcagtt ccttgcatag acataaaaag actcactgga aaaaaactca   2160

cactggagag aacccgtatg gatgtaagga atgtgggaaa gcatttgctt ctctcagttc   2220

cttgcataga cataaaaaga ctcactagca ttctctctaa atgtatggaa tgtgggaaag   2280

catttattaa ttttatttca tttcagatac ttgtacgaaa cacattggag atagaccctg   2340

tgaatgtaag cacttggtaa aaccttaagt aatttcagtt tctttccagt acagtcatcc   2400

cttgatacct gctgggtatt ggttccagca ctccgtgagc catgtccagt cccttttata   2460

aaatgacata tttgtatgta acttacccac atcctcttgt atactctcaa ttatgtctag   2520

attacttaaa atacctcatg cattgtaaaa gctatgcaaa tagttgttct attgtattgt   2580

ttagggactc atgataagga aaagagtcta tgtattttca gtatagatgc agtaattgtc   2640

agcctatcaa catagtatag tcagccagaa cattaaagtt tctttgtttc aactctc      2697


<210>  9171
<211>  611
<212>  PRT
<213>  Homo sapiens

<400>  9171

Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
1               5                   10                  15


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
            20                  25                  30


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
        35                  40                  45


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
    50                  55                  60


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
65                  70                  75                  80


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
                85                  90                  95


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
            100                 105                 110


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
        115                 120                 125


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
    130                 135                 140


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
145                 150                 155                 160


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
                165                 170                 175


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
            180                 185                 190


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
        195                 200                 205


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
    210                 215                 220


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
225                 230                 235                 240


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
                245                 250                 255


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
            260                 265                 270


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
        275                 280                 285


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
    290                 295                 300


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
305                 310                 315                 320


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                325                 330                 335


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
            340                 345                 350


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
        355                 360                 365


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
    370                 375                 380


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
385                 390                 395                 400


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
                405                 410                 415


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
            420                 425                 430


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
        435                 440                 445


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
    450                 455                 460


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
465                 470                 475                 480


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
                485                 490                 495


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
            500                 505                 510


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
        515                 520                 525


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
    530                 535                 540


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
545                 550                 555                 560


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
                565                 570                 575


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
            580                 585                 590


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
        595                 600                 605


Lys Thr His 
    610


<210>  9172
<211>  2582
<212>  DNA
<213>  Homo sapiens

<400>  9172
gtcaatcagg cgcgcttccc agaggagtgt gtggttgaaa aagcccgcgg cgtcttctcc     60

acccacctgc gctgggcgct cggtgctcgg ctctgtagct aagagacgac ctggaagttc    120

cgtggcagcc tgtgtcccgc gggaacccgc attggcagcg ggagccgtcc ggaggacctg    180

ggacaccgcg gaagtcggga aatggcctca gtggctttag aggatgtggc tgtgaacttc    240

acccgagaag agtgggcttt gctgggtcct tgtcagaaga atctctacaa agatgtgatg    300

caggaaacca tcaggaacct ggattgtgta ggaatgaaat ggaaagacca gaacattgaa    360

gatcaatata gatatcccag gaaaaatcta agatgtcgta tgttagagag atttgttgaa    420

agtaaagatg gaactcaatg tggagaaaca tctagccaga ttcaagatag tattgtgacc    480

aagaacactc ttcctggagt aggtccatat gaaagccgta tgagtggaga agtcatcatg    540

ggtcattcat cccttaattg ttacatcaga gttggtgctg ggcacaaacc atatgagtat    600

catgaatgtg gagagaagcc agatacgcat aaacaacgtg ggaaagcctt cagttaccac    660

aactcacttc aaacacatga gaggcttcac actggaaaga aaccatataa ttgtaaagaa    720

tgtgggaagt ccttcagttc tttgggaaac cttcaaagac acatggcagt gcagcgtgga    780

gatggacctt ataaatgtaa gttgtgtggg aaagcgtttt tttggcccag tttattacat    840

atgcatgaga gaacgcacac tggagagaaa ccatatgaat gtaagcagtg ttctaaagcc    900

ttttcttttt acagttccta tctaagacat gaaagaacac atactgggga gaaactgtat    960

gaatgtaaac agtgttctaa agccttccct gattacagtt cttgtctaag acatgaaaga   1020

actcacactg gaaagaaacc ctatacatgt aaacaatgtg ggaaagcctt cagtgcttcc   1080

acttcccttc gaagacacga aacaactcac actgatgaga aaccctatgc atgtcagcaa   1140

tgtgggaaag cgtttcatca tctgggaagc tttcaaagac acatggtaat gcacacgaga   1200

gatggacctc ataagtgtaa gatatgtgga aaaggctttg attgtcctag ttcactgaaa   1260

agtcatgaaa gaactcacac tggagagaaa ctctatgaat gcaagcagtg tgggaaagcg   1320

ttatctcata gctcaagctt tcgaagacac atgacaatgc acactggaga tggacctcac   1380

aaatgcaaga tatgtgggaa agcctttgtt tatcccagtg tatttcaaag gcatgaaaag   1440

actcacactg cagagaaacc ctataaatgt aaacaatgtg gcaaagccta ccgtatttcc   1500

agttctcttc gaaggcatga aacaactcat actggagaga aaccctataa atgcaaatgt   1560

gggaaagcct ttattgattt ctattccttt caaaatcaca aaacaactca tgctggagag   1620

aagccatatg agtgtaagga atgtgggaaa gcattcagtt gtttccaata cctttctcaa   1680

catagaagga ctcacacagg agagaaacct tatgagtgta acacatgtaa gaaagccttc   1740

agtcattttg gtaacttaaa agtacatgaa agaattcact ctggagagaa gccgtatgaa   1800

tgtaaggaat gtgggaaagc attctcttgg ctcacttgct ttctacgaca tgaaagaatt   1860

cacatgagag agaaacccta tgagtgtcaa caatgtggta aagccttcac tcattcccgt   1920

tttcttcaag gacatgaaaa aactcatact ggagagaacc cgtatgaatg taaggaatgt   1980

gggaaagcat ttgcttctct cagttccttg catagacata aaaagactca ctggaaaaaa   2040

actcacactg gagagaaccc gtatggatgt aaggaatgtg ggaaagcatt tgcttctctc   2100

agttccttgc atagacataa aaagactcac tagcattctc tctaaatgta tggaatgtgg   2160

gaaagcattt attaatttta tttcatttca gatacttgta cgaaacacat tggagataga   2220

ccctgtgaat gtaagcactt ggtaaaacct taagtaattt cagtttcttt ccagtacagt   2280

catcccttga tacctgctgg gtattggttc cagcactccg tgagccatgt ccagtccctt   2340

ttataaaatg acatatttgt atgtaactta cccacatcct cttgtatact ctcaattatg   2400

tctagattac ttaaaatacc tcatgcattg taaaagctat gcaaatagtt gttctattgt   2460

attgtttagg gactcatgat aaggaaaaga gtctatgtat tttcagtata gatgcagtaa   2520

ttgtcagcct atcaacatag tatagtcagc cagaacatta aagtttcttt gtttcaactc   2580

tc                                                                  2582


<210>  9173
<211>  643
<212>  PRT
<213>  Homo sapiens

<400>  9173

Met Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr Arg Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Gly Met Lys Trp Lys 
        35                  40                  45


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
    50                  55                  60


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
65                  70                  75                  80


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
                85                  90                  95


Leu Pro Gly Val Gly Pro Tyr Glu Ser Arg Met Ser Gly Glu Val Ile 
            100                 105                 110


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
        115                 120                 125


Lys Pro Tyr Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Leu Gln Thr His Glu 
145                 150                 155                 160


Arg Leu His Thr Gly Lys Lys Pro Tyr Asn Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
225                 230                 235                 240


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Phe Pro Asp Tyr Ser Ser Cys Leu Arg His Glu 
            260                 265                 270


Arg Thr His Thr Gly Lys Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ser Ala Ser Thr Ser Leu Arg Arg His Glu Thr Thr His Thr 
    290                 295                 300


Asp Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His 
305                 310                 315                 320


Leu Gly Ser Phe Gln Arg His Met Val Met His Thr Arg Asp Gly Pro 
                325                 330                 335


His Lys Cys Lys Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu 
            340                 345                 350


Lys Ser His Glu Arg Thr His Thr Gly Glu Lys Leu Tyr Glu Cys Lys 
        355                 360                 365


Gln Cys Gly Lys Ala Leu Ser His Ser Ser Ser Phe Arg Arg His Met 
    370                 375                 380


Thr Met His Thr Gly Asp Gly Pro His Lys Cys Lys Ile Cys Gly Lys 
385                 390                 395                 400


Ala Phe Val Tyr Pro Ser Val Phe Gln Arg His Glu Lys Thr His Thr 
                405                 410                 415


Ala Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile 
            420                 425                 430


Ser Ser Ser Leu Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro 
        435                 440                 445


Tyr Lys Cys Lys Cys Gly Lys Ala Phe Ile Asp Phe Tyr Ser Phe Gln 
    450                 455                 460


Asn His Lys Thr Thr His Ala Gly Glu Lys Pro Tyr Glu Cys Lys Glu 
465                 470                 475                 480


Cys Gly Lys Ala Phe Ser Cys Phe Gln Tyr Leu Ser Gln His Arg Arg 
                485                 490                 495


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Asn Thr Cys Lys Lys Ala 
            500                 505                 510


Phe Ser His Phe Gly Asn Leu Lys Val His Glu Arg Ile His Ser Gly 
        515                 520                 525


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu 
    530                 535                 540


Thr Cys Phe Leu Arg His Glu Arg Ile His Met Arg Glu Lys Pro Tyr 
545                 550                 555                 560


Glu Cys Gln Gln Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln 
                565                 570                 575


Gly His Glu Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu 
            580                 585                 590


Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys 
        595                 600                 605


Thr His Trp Lys Lys Thr His Thr Gly Glu Asn Pro Tyr Gly Cys Lys 
    610                 615                 620


Glu Cys Gly Lys Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys 
625                 630                 635                 640


Lys Thr His 



<210>  9174
<211>  2570
<212>  DNA
<213>  Homo sapiens

<400>  9174
gctgagagac gacctggaag ttctgaggca gcctttgtct ggctggaaca cgcattggca     60

gcgggagctg tcggtaggac ctgggacacc gcggaagtcg ggaaatggcc tcagtggctt    120

tagaggatgt ggctgtgaac ttcacccgag aagagtgggc tttgctgggt ccttgtcaga    180

agaatctcta caaagatgtg atgcaggaaa ccatcaggaa cctggattgt gtagtaatga    240

aatggaaaga ccagaacatt gaagatcaat atagatatcc caggaaaaat ctaagatgtc    300

gtatgttaga gagatttgtt gaaagtaaag atggaactca atgtggagaa acatctagcc    360

agattcaaga tagtattgtg accaagaaca ctcttcctgg agtaggtcct tgtgaaagca    420

gtatgagagg agaaaaagtc atgggtcatt catcccttaa ttgttacatc agagttggtg    480

ctgggcacaa accacatgag tatcatgaat gtggagagaa gccagatacg cataaacaac    540

gtgggaaagc cttcagttac cacaactcat ttcaaacaca tgagaggctt cacactggaa    600

agaaaccata tgattgtaaa gaatgtggga agtccttcag ttctttggga aaccttcaaa    660

gacacatggc agtgcagcgt ggagatggac cttataaatg taagttgtgt gggaaagcgt    720

ttttttggcc cagtttatta catatgcatg aaagaacgca cactggagag aaaccatatg    780

aatgtaagca gtgttctaaa gccttttctt tttacagttc ctatctaaga catgaaagaa    840

cacatactgg ggagaaaccg tatgaatgta aacagtgttc taaagccttt cctttttaca    900

gttcctatct aagacatgaa agaacacata ctggggagaa accatataaa tgtaagcagt    960

gttctaaagc cttccctgat tccagttctt gtctaataca tgaaagaact cacactggag   1020

agaaacccta tacatgtaaa caatgtggga aagccttcag tgtttccggt tcccttcaaa   1080

gacatgaaac cactcacagt gcagagaaac cctatgcatg tcagcaatgt gggaaagcgt   1140

ttcatcatct gggaagcttt caaagacaca tgataaggca cactggaaat ggacctcata   1200

aatgtaagat atgtgggaaa ggctttgatt gtcctagttc actgcaaagt catgaaagaa   1260

ctcacactgg agagaaaccc tatgaatgca agcagtgtgg gaaagcatta tctcatcgct   1320

caagctttcg aagtcatatg ataatgcaca ctggagatgg acctcataaa tgcaaggtat   1380

gtgggaaagc ctttgtttat cccagtgtat ttcaaagaca tgaaaggact cacactgcag   1440

agaaacccta taaatgtaaa caatgtggca aagcctaccg tatttccagt tcccttcgaa   1500

ggcatgaaac aactcatact ggagagaaac cctataaatg caaacttggg aaagcctgta   1560

ttgatttctg ttcctttcaa aatcacaaaa caactcacac tggagagaag ccatatgagt   1620

gtaaggaatg tgggaaagca ttcagtcgtt tcagatacct ttctcgacat aaaaggactc   1680

acacaggaga gaaaccttat gagtgtaaaa catgtaggaa agccttcggt cattatgata   1740

acttaaaggt acatgaaaga attcactctg gagagaagcc gtatgaatgt aaggaatgtg   1800

ggaaagcatt ctcttggctc acttgctttc tacgacatga aagaattcac atgagagaga   1860

aatcctatga atgtccacaa tgtggtaaag ccttcactca ttcccgtttt cttcaaggac   1920

atgaaaaaac tcatactgga gagaacccgt atgaatgtaa ggaatgtggg aaagcatttg   1980

cttctctcag ttccttgcat agacataaaa agactcactg gaaaaaaact cacactggag   2040

agaacccata tgaatgtaag gaatgtggga aagcatttgc ttctctcagt tccttgcata   2100

gacataaaaa gactcactag cattctctct aaatgtatgg aatgtgggaa agcatttatt   2160

aattttattt catttcagat acttgtacga aacacattgg agatagaccc tgtgaatgta   2220

agcacttggt aaagccttaa gtagtttcag tttctttcca gtacagtcat cccttgatac   2280

ctgctgggta ttggttccag cactccgtga gccatgtcca gtccctttta taaaatgaca   2340

tgtttgtatg taacttaccc acatcctctt gtatagtctc aattatgtct agattactta   2400

aaatacctca tgcattataa aagctatgca aatagttgtt ctattgtatt gtttagggaa   2460

tcatgataag gaaaagagtc tatgtatttt cagtatagat gcagtaattg tgagcctatc   2520

aacatagtgt agtcagccag aacattaaag tttctttgtt tcaactctca              2570


<210>  9175
<211>  671
<212>  PRT
<213>  Homo sapiens

<400>  9175

Met Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr Arg Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Val Met Lys Trp Lys 
        35                  40                  45


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
    50                  55                  60


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
65                  70                  75                  80


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
                85                  90                  95


Leu Pro Gly Val Gly Pro Cys Glu Ser Ser Met Arg Gly Glu Lys Val 
            100                 105                 110


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
        115                 120                 125


Lys Pro His Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Phe Gln Thr His Glu 
145                 150                 155                 160


Arg Leu His Thr Gly Lys Lys Pro Tyr Asp Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
225                 230                 235                 240


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Phe Pro Phe Tyr Ser Ser Tyr Leu Arg His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Gln Cys Ser Lys 
        275                 280                 285


Ala Phe Pro Asp Ser Ser Ser Cys Leu Ile His Glu Arg Thr His Thr 
    290                 295                 300


Gly Glu Lys Pro Tyr Thr Cys Lys Gln Cys Gly Lys Ala Phe Ser Val 
305                 310                 315                 320


Ser Gly Ser Leu Gln Arg His Glu Thr Thr His Ser Ala Glu Lys Pro 
                325                 330                 335


Tyr Ala Cys Gln Gln Cys Gly Lys Ala Phe His His Leu Gly Ser Phe 
            340                 345                 350


Gln Arg His Met Ile Arg His Thr Gly Asn Gly Pro His Lys Cys Lys 
        355                 360                 365


Ile Cys Gly Lys Gly Phe Asp Cys Pro Ser Ser Leu Gln Ser His Glu 
    370                 375                 380


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys 
385                 390                 395                 400


Ala Leu Ser His Arg Ser Ser Phe Arg Ser His Met Ile Met His Thr 
                405                 410                 415


Gly Asp Gly Pro His Lys Cys Lys Val Cys Gly Lys Ala Phe Val Tyr 
            420                 425                 430


Pro Ser Val Phe Gln Arg His Glu Arg Thr His Thr Ala Glu Lys Pro 
        435                 440                 445


Tyr Lys Cys Lys Gln Cys Gly Lys Ala Tyr Arg Ile Ser Ser Ser Leu 
    450                 455                 460


Arg Arg His Glu Thr Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys 
465                 470                 475                 480


Leu Gly Lys Ala Cys Ile Asp Phe Cys Ser Phe Gln Asn His Lys Thr 
                485                 490                 495


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala 
            500                 505                 510


Phe Ser Arg Phe Arg Tyr Leu Ser Arg His Lys Arg Thr His Thr Gly 
        515                 520                 525


Glu Lys Pro Tyr Glu Cys Lys Thr Cys Arg Lys Ala Phe Gly His Tyr 
    530                 535                 540


Asp Asn Leu Lys Val His Glu Arg Ile His Ser Gly Glu Lys Pro Tyr 
545                 550                 555                 560


Glu Cys Lys Glu Cys Gly Lys Ala Phe Ser Trp Leu Thr Cys Phe Leu 
                565                 570                 575


Arg His Glu Arg Ile His Met Arg Glu Lys Ser Tyr Glu Cys Pro Gln 
            580                 585                 590


Cys Gly Lys Ala Phe Thr His Ser Arg Phe Leu Gln Gly His Glu Lys 
        595                 600                 605


Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala 
    610                 615                 620


Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys Thr His Trp Lys 
625                 630                 635                 640


Lys Thr His Thr Gly Glu Asn Pro Tyr Glu Cys Lys Glu Cys Gly Lys 
                645                 650                 655


Ala Phe Ala Ser Leu Ser Ser Leu His Arg His Lys Lys Thr His 
            660                 665                 670


<210>  9176
<211>  2663
<212>  DNA
<213>  Homo sapiens

<400>  9176
gtagctgaga gacgacctgg aagttctgag gcagcctttg tctggctgga acacgcattg     60

gcagcgggag ctgtcggtag gacctgggac accgcggaag tcgggaaatg gcctcagtgg    120

ctttagagga tgtggctgtg aacttcaccc gagaagagtg ggctttgctg ggtccttgtc    180

agaagaatct ctacaaagat gtgatgcagg aaaccatcag gaacctggat tgtgtagtaa    240

tgaaatggaa agaccagaac attgaagatc aatatagata tcccaggaaa aatctaaggt    300

aatttacact cacaagagaa agatatgtcc ctggagccgt tctgagaatg acatgaaaat    360

ttaaaaagaa gcaaagaaaa tgaacaagat gtcgtatgtt agagagattt gttgaaagta    420

aagatggaac tcaatgtgga gaaacatcta gccagattca agatagtatt gtgaccaaga    480

acactcttcc tggagtaggt ccttgtgaaa gcagtatgag aggagaaaaa gtcatgggtc    540

attcatccct taattgttac atcagagttg gtgctgggca caaaccacat gagtatcatg    600

aatgtggaga gaagccagat acgcataaac aacgtgggaa agccttcagt taccacaact    660

catttcaaac acatgagagg cttcacactg gaaagaaacc atatgattgt aaagaatgtg    720

ggaagtcctt cagttctttg ggaaaccttc aaagacacat ggcagtgcag cgtggagatg    780

gaccttataa atgtaagttg tgtgggaaag cgtttttttg gcccagttta ttacatatgc    840

atgaaagaac gcacactgga gagaaaccat atgaatgtaa gcagtgttct aaagcctttt    900

ctttttacag ttcctatcta agacatgaaa gaacacatac tggggagaaa ccgtatgaat    960

gtaaacagtg ttctaaagcc tttccttttt acagttccta tctaagacat gaaagaacac   1020

atactgggga gaaaccatat aaatgtaagc agtgttctaa agccttccct gattccagtt   1080

cttgtctaat acatgaaaga actcacactg gagagaaacc ctatacatgt aaacaatgtg   1140

ggaaagcctt cagtgtttcc ggttcccttc aaagacatga aaccactcac agtgcagaga   1200

aaccctatgc atgtcagcaa tgtgggaaag cgtttcatca tctgggaagc tttcaaagac   1260

acatgataag gcacactgga aatggacctc ataaatgtaa gatatgtggg aaaggctttg   1320

attgtcctag ttcactgcaa agtcatgaaa gaactcacac tggagagaaa ccctatgaat   1380

gcaagcagtg tgggaaagca ttatctcatc gctcaagctt tcgaagtcat atgataatgc   1440

acactggaga tggacctcat aaatgcaagg tatgtgggaa agcctttgtt tatcccagtg   1500

tatttcaaag acatgaaagg actcacactg cagagaaacc ctataaatgt aaacaatgtg   1560

gcaaagccta ccgtatttcc agttcccttc gaaggcatga aacaactcat actggagaga   1620

aaccctataa atgcaaactt gggaaagcct gtattgattt ctgttccttt caaaatcaca   1680

aaacaactca cactggagag aagccatatg agtgtaagga atgtgggaaa gcattcagtc   1740

gtttcagata cctttctcga cataaaagga ctcacacagg agagaaacct tatgagtgta   1800

aaacatgtag gaaagccttc ggtcattatg ataacttaaa ggtacatgaa agaattcact   1860

ctggagagaa gccgtatgaa tgtaaggaat gtgggaaagc attctcttgg ctcacttgct   1920

ttctacgaca tgaaagaatt cacatgagag agaaatccta tgaatgtcca caatgtggta   1980

aagccttcac tcattcccgt tttcttcaag gacatgaaaa aactcatact ggagagaacc   2040

cgtatgaatg taaggaatgt gggaaagcat ttgcttctct cagttccttg catagacata   2100

aaaagactca ctggaaaaaa actcacactg gagagaaccc atatgaatgt aaggaatgtg   2160

ggaaagcatt tgcttctctc agttccttgc atagacataa aaagactcac tagcattctc   2220

tctaaatgta tggaatgtgg gaaagcattt attaatttta tttcatttca gatacttgta   2280

cgaaacacat tggagataga ccctgtgaat gtaagcactt ggtaaagcct taagtagttt   2340

cagtttcttt ccagtacagt catcccttga tacctgctgg gtattggttc cagcactccg   2400

tgagccatgt ccagtccctt ttataaaatg acatgtttgt atgtaactta cccacatcct   2460

cttgtatagt ctcaattatg tctagattac ttaaaatacc tcatgcatta taaaagctat   2520

gcaaatagtt gttctattgt attgtttagg gaatcatgat aaggaaaaga gtctatgtat   2580

tttcagtata gatgcagtaa ttgtgagcct atcaacatag tgtagtcagc cagaacatta   2640

aagtttcttt gtttcaactc tca                                           2663


<210>  9177
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  9177

Met Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr Arg Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Val Met Lys Trp Lys 
        35                  40                  45


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
    50                  55                  60


<210>  9178
<211>  1041
<212>  DNA
<213>  Homo sapiens

<400>  9178
aactgtcaat caggcactgc ccagagaagt gtgtgtggtt gaaaaagccc gcggcgtctg     60

ctccacccac ctgcgctcgg ctctgggttc tgtagctgag agacgacctg gaagttctga    120

ggcagccttt gtctggctgg aacacgcatt ggcagcggga gctgtcggta ggacctggga    180

caccgcggaa gtcgggaaat ggcctcagtg gctttagagg atgtggctgt gaacttcacc    240

cgagaagagt gggctttgct gggtccttgt cagaagaatc tctacaaaga tgtgatgcag    300

gaaaccatca ggaacctgga ttgtgtagta atgaaatgga aagaccagaa cattgaagat    360

caatatagat atcccaggaa aaatctaaga tgtcgtatgt tagagagatt tgttgaaagt    420

aaagatggaa ctcaatgtgg agaaacatct agccagattc aagatagtat tgtgaccaag    480

aacactcttc ctggagtagg tccttgtgaa agcagtatga gaggagaaaa agtcatgggt    540

cattcatccc ttaattgtta catcagagtt ggtgctgggc acaaaccaca tgagtatcat    600

gaatgtggag agaagccaga tacgcataaa caacgtggga aagccttcag ttaccacaac    660

tcatttcaaa cacatgagag gcttcacact ggaaagaaac catatgattg taaagaatgt    720

gggaagtcct tcagttcttt gggaaacctt caaagacaca tggcagtgca gcgtggagat    780

ggaccttata aatgtaagtt gtgtgggaaa gcgttttttt ggcccagttt attacatatg    840

catgaaagaa cgcacactgg agagaaacca tatgaatgta agcagtgttc taaagccttt    900

tctttttaca gttcctatct aagacatgaa agaacacata ctggggagaa accgtatgaa    960

tgtaaacagt gttctaaagc ctttcctttt tacagttcct atctaaacat gaaaggactc   1020

acactgcaga gaaaccctat a                                             1041


<210>  9179
<211>  280
<212>  PRT
<213>  Homo sapiens

<400>  9179

Met Ala Ser Val Ala Leu Glu Asp Val Ala Val Asn Phe Thr Arg Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Cys Gln Lys Asn Leu Tyr Lys Asp Val 
            20                  25                  30


Met Gln Glu Thr Ile Arg Asn Leu Asp Cys Val Val Met Lys Trp Lys 
        35                  40                  45


Asp Gln Asn Ile Glu Asp Gln Tyr Arg Tyr Pro Arg Lys Asn Leu Arg 
    50                  55                  60


Cys Arg Met Leu Glu Arg Phe Val Glu Ser Lys Asp Gly Thr Gln Cys 
65                  70                  75                  80


Gly Glu Thr Ser Ser Gln Ile Gln Asp Ser Ile Val Thr Lys Asn Thr 
                85                  90                  95


Leu Pro Gly Val Gly Pro Cys Glu Ser Ser Met Arg Gly Glu Lys Val 
            100                 105                 110


Met Gly His Ser Ser Leu Asn Cys Tyr Ile Arg Val Gly Ala Gly His 
        115                 120                 125


Lys Pro His Glu Tyr His Glu Cys Gly Glu Lys Pro Asp Thr His Lys 
    130                 135                 140


Gln Arg Gly Lys Ala Phe Ser Tyr His Asn Ser Phe Gln Thr His Glu 
145                 150                 155                 160


Arg Leu His Thr Gly Lys Lys Pro Tyr Asp Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Ser Phe Ser Ser Leu Gly Asn Leu Gln Arg His Met Ala Val Gln Arg 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Lys Leu Cys Gly Lys Ala Phe Phe Trp 
        195                 200                 205


Pro Ser Leu Leu His Met His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Lys Gln Cys Ser Lys Ala Phe Ser Phe Tyr Ser Ser Tyr 
225                 230                 235                 240


Leu Arg His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
                245                 250                 255


Gln Cys Ser Lys Ala Phe Pro Phe Tyr Ser Ser Tyr Leu Asn Met Lys 
            260                 265                 270


Gly Leu Thr Leu Gln Arg Asn Pro 
        275                 280


<210>  9180
<211>  695
<212>  DNA
<213>  Homo sapiens

<400>  9180
tacgcttgat gcaccactac ctttctaacc tcacaccctc acctgtttac ccctacgtcc     60

tcaagacctg cttctttgtt tgatcaccaa taaataatgt gggctcccag agctcagggc    120

cttcgcagca tccataccag cgttggcccc ctggacccac cttatgcact cttaacttgt    180

cttttctcat tcctttgact acgctggagt ttgtagcccc cacggcctgg tgttgggtct    240

gatcacccca acatttctgg cacccaacgt ggggctacga acactccggt gaaggaacac    300

tagagtgtgc ggaagcggag gacacattgt cagaggacac ccaaggacga ctgaaagaag    360

cttggtggaa ttcatataaa gttgcgagtt tcaggttggt tggctctgac tgatcacctg    420

tattatggac catctgtgtg attatgggga aaagttcagg acaccagcaa cctacattgg    480

ataggaccac ctctgactcc agggattgcc actcaatctt tctgagatta gcacccacat    540

ccaacaaggt gtgatcctgg tgatctttga aaaaaaggca ctgaaacaac catgatttaa    600

gtttttggta ttatgaatgc atgagaaatt ttctgggaaa aaatcataac tatattaaga    660

ataaaaaata aaaaattcct aaggaaaata cttga                               695


<210>  9181
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  9181

Met Gly Lys Ser Ser Gly His Gln Gln Pro Thr Leu Asp Arg Thr Thr 
1               5                   10                  15


Ser Asp Ser Arg Asp Cys His Ser Ile Phe Leu Arg Leu Ala Pro Thr 
            20                  25                  30


Ser Asn Lys Val 
        35


<210>  9182
<211>  4178
<212>  DNA
<213>  Homo sapiens

<400>  9182
agccgctgcg ctccgctctg gggtctcctc accccagaag gccctcaggt ggaggaaggg     60

cctcaggtgg aggtaggacc tgtgctggcc gcgggagagg taaacagaac accaggacat    120

cccagagtct gggaaatggc ccaaatacat tttctttgtg gatctgcatg acttatggta    180

ccctcctcat ctgggctgtg aatatatatg actaataaac tgttgtcagt tgcatttgtc    240

cagtgatgga tatcatgtgt tagcctacct aaatagccct agggccctaa ttcctctctc    300

accaatgggg tgagtgggag gctattgaaa catgcacatc catgataccc catggtcagg    360

cactgatgag caaagaaaag aaggtacatt tggtatcaat cctttccaaa gcatgagagg    420

atgtaactca actgttcttc caaagcaaaa caagtagcca gggggctaca ttgttttctg    480

tagtactgct gcttaccagc atgtcaaagg gataatcttg agatcacaag gccgttggtt    540

cccaccaggg tcttaggcaa aattaccttg ttggatgtgg gtgctaatct cagaaagatt    600

gagtggcaat ccctggagtc agaggtggtc ctatccaatg taggttgctg gtgtcctgaa    660

cttttcccca taatcacaca gatggtccat aatacaggtg atcagtcaga gccaaccaac    720

ctgaaactcg caactttata tgaattctga gggatttttt acagaaagaa aagggaaaag    780

caatgattag gtggcatgct caggtccata aacctaatag cagatagaag caaatttctc    840

ccacttgata aagaacctct aaaaagaagc caagctaaga tcatacttaa ttttgatatc    900

tagatgcttt cccactgaga tcaggaacga ggtaaggatg cctcctctca ccactgctat    960

tcatcatcat cctagatgtc ctcactaatg gaataaaaca agaaattttt tcttcaatta   1020

attgaagttc ctctaaggcc tctttggaca gggagcattt actgtttaag ttagaatcac   1080

ctcgtaaggt agaaaagagg tgagacatag cataagtagg aatgcctaaa gtgggacaaa   1140

tccaattaat gtctcctaat gatttttaaa attatttagt ctataaatta tctcttctaa   1200

tttgaacttt ttgaggttta atagtacttt gttttacttt cattcgtaaa tactgaaagg   1260

gagtagaagt ttggatttta ttgggggcta tgattaaccc tgctgcagtt acagcctttt   1320

ctaactgttt gtagcatagc attaatcctc cctagtttca gctgcacata aaatatcacc   1380

cacgtagtgg ataatataac attttttgaa ttgttctcta actagcttaa tagcttttcc   1440

aacataagtt tgacaaatag tcgggcaatt taacatgcct tgtggcagta cttttcaatg   1500

gtatctgtcc gctggttctt tgttatttat agtgggaaca gtaaaagcaa ttttttcata   1560

atctcgagta gctaaaggaa tggtagaaaa gcaatttttt aaatctatta ctatgagagg   1620

tcagtatttt gggatcattg ttggagaggg cagccctggt tcagtgagcc catgggctga   1680

attatagcat taacagccct caaatctgtt aacattctcc atttccctga ttttttctta   1740

ataacaaaca caggagaatt ccaaggggag aaagtaggct ctatgtgtcc cttttgtaat   1800

tgatcctgca ctaattcttt taaagcctcc ggtttttcct gtttcagcgg ccattgctcc   1860

acccaaaccg gtttggcagt taaccaaaca agcggaatgg gagccggagg ctcagcaatt   1920

gcagctccta aaaatgatac cctgatccag ttcgatctgt ttgccttttt agttctaaag   1980

gttctggttg gccattttta tttttttttt cctagtccct tccctgggag atatcccatt   2040

tttctcatca tttgtttact gttattatta tactgatcca taggaataga tattttagca   2100

ctccattgtt gtaataagtc tctaccccat agattgacag gaataggtgt aacaataggt   2160

tgaattgtcc cttcttggcc atccagccct tggcatggca aaattaaaga actttaaaaa   2220

attctgaggc agcccctact ccaacaatac caatggatgc cttctgctta ggccaatgcc   2280

ggggccattg atttaaacca ataatagaaa catcagctcc agtatctact aacccttcaa   2340

agtcctttcc ttgaatggtt actgtacaaa taggtctctt atcagacact tgattaaccc   2400

aatatacagc ttttcctgct ggattcgtac caccaaagcc tcctattttt tttttttcta   2460

ctgtgcctct tcccagtttt gcataaggta acagtaacaa ctgagcaatt ctttctcctg   2520

ggaaagcaga ccatggaatt gaggaactaa taactaactg aatctctccg gtataattag   2580

aatcaattat ttatgtacag cgacacctct taaatttaaa ttagaccttc caagcaatag   2640

accaactgtt cctgagggta aagggctcct aactctcatg ggacgttctt tggtggctcc   2700

ccaggaagta gggaaacggg aattgtgctg cagagatcta cagcagcgct gcctgctgtg   2760

gcgggggaca attgttgtat gtttgtaagg gcactgactg tgccggatat gcctcagttt   2820

gttgaggggc ccaaggtggg cccctattcc cgtttcccga aagaggttgc ccatctttgc   2880

tagatttaga atgacactga tttgcccagt gattgccctt cttacattgg gggcatacac   2940

ctggactttt ctgttgattg atggcaatag tttttgcctt ctgatttcct tttctacatt   3000

cctcttttat gtgtccaaat tgcccacaat taaaacaaga gcctgagaaa tggggcatat   3060

tttttcccac ctttagtcaa gccatagctg gactaaaatt ttccccagtg ccatcacaag   3120

ccttaatata ttcagccaaa tgagtcttcc ctctcatagg tctaatgaaa gaaggatatt   3180

tttaccctgt aacatttttt ttccatgcct gtaagcacac agtgcataac tgaacaatgg   3240

caacattttt cattactgct tgattgtcta atcggcccca attagggccc aaccccatta   3300

actgttcaaa ggaaacaggc acaggcagct gtgcttgtgt gttttctctt gcctgagttt   3360

gagctttatc agcccaccaa gttttaaact gcaaacactg agatggagtg agaacagatt   3420

ttgttaaagt atcccagtca tatggtatta atctattatc aagagccaca ttttttagta   3480

aagtttgtac aaaaggagaa tttggcctat attgactaat ggcttgcttg aattccttta   3540

acaacttaaa aggaaaggtg gcccaactag ctatattctg tcctcctctc tggattatag   3600

taatgggaaa ttgccatgct tctaggtctc cttcagttct agccttctga ataaaatttt   3660

atatcgcatc accaattgct ccaggtttta atgttgcagc taccggagcg gtaagtttta   3720

cagctaattc atcttctcac ccattagggg gagagggagg aggtggccat tcacttaatt   3780

cagcaggtgg aaccgaaggg ctagtaaaat ataccttttt cagtttccat ttcttttctt   3840

taatttcttc cggttgctgt tcctcatatt cagaatctga agttaatttt ttacactcat   3900

ctacctcttc ctcatctgaa tctgccttgt catctgtttg aaatggctca agaactgcct   3960

ttatcaactc ccacactgac caaacagaaa ctggaatttt ggctccttct ttatatgcgt   4020

ttttaaaatt tctgccaatt cttccccatt catctagctc cattgtcctt tgttctggga   4080

accatgggca aaactgctct actgtatcaa agagtgttaa taagttctga gtattaactt   4140

tcactccccc tctccataat aaatgcctta agaaattt                           4178


<210>  9183
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  9183

Met Gly Ala Gly Gly Ser Ala Ile Ala Ala Pro Lys Asn Asp Thr Leu 
1               5                   10                  15


Ile Gln Phe Asp Leu Phe Ala Phe Leu Val Leu Lys Val Leu Val Gly 
            20                  25                  30


His Phe Tyr Phe Phe Phe Pro Ser Pro Phe Pro Gly Arg Tyr Pro Ile 
        35                  40                  45


Phe Leu Ile Ile Cys Leu Leu Leu Leu Leu Tyr 
    50                  55


<210>  9184
<211>  2154
<212>  DNA
<213>  Homo sapiens

<400>  9184
gcgcaaacgg cgagggcgtg gctaccagcc gctgcgctcc gctctggggt ctcctcaccc     60

cagaaggccc tcaggtggag gaagggcctc aggtggaggt aggacctgtg ctggccgcgg    120

gagaggtaaa cagaacacca ggacatccca gagtctggga aatggactca gtggtctttg    180

aggatgtggc tgtgaacttc acccaggagg agtgggcttt gctgggtccc tctcagaaga    240

aactctacag agatgtgatg caagaaacct ttgttaactt ggcctctata ggggaaaact    300

gggaggagaa gaacattgaa gatcacaaaa atcaggggag aaagctaaga agtcatatgg    360

tagagaggct ctgtgaaagg aaagaaggta gtcagtttgg agaaaccatc agtcagactc    420

caaatcctaa accaaacaag aaaactttta ctagagtaaa accatatgaa tgtagtgtgt    480

gtggaaagga ctatatgtgt cattcatctc ttaataggca catgagatct catactgaac    540

atagatcata tgaatatcac aaatatggag agaaatcata tgaatgtaag gaatgtggga    600

aaagattcag ctttcgaagt tcatttcgaa tacatgaaag aactcacact ggagagaaac    660

cctataaatg taaacagtgt ggtaaggctt tcagttggcc cagttccttt caaatacatg    720

aaagaactca tactggagag aaaccttatg aatgtaagga atgtgggaag gccttcattt    780

atcacacaac ctttcgagga cacatgagaa tgcacacagg ggagaaaccc tataaatgta    840

aagaatgcgg gaaaacgttc agtcatccca gttcttttcg aaatcatgaa agaactcact    900

ctggagagaa accctatgaa tgtaaacaat gtggaaaagc tttcagatat taccaaactt    960

ttcaaataca tgaaaggact cacactgggg aaaaacccta tcagtgtaag caatgtggta   1020

aagctcttag ttgtcccaca tcctttcgaa gtcatgaaag gattcacact ggagaaaaac   1080

cctataaatg taaaaaatgt gggaaagcct tcagttttcc tagttccttt agaaaacatg   1140

aaagaattca tacaggagag aaaccctatg attgtaagga atgtgggaaa gcattcattt   1200

ctcttccaag ctatcgaaga catatgataa tgcacactgg aaatggacct tataaatgca   1260

aggaatgtgg gaaagccttt gattgtccta gttcttttca aatccatgaa cgaactcaca   1320

ctggagagaa accctatgaa tgtaaacagt gtggtaaagc cttcagttgt tccagttcct   1380

ttcgaatgca tgaaagaact cacactggag agaaacccca tgaatgtaaa caatgtggta   1440

aagccttcag ttgttccagt tctgttcgaa tacatgaaag gactcacact ggagagaaac   1500

cctatgaatg taaacagtgt ggtaaagcct tcagttgttc cagttccttt cgaatgcatg   1560

aaagaattca cactggagag aaaccctatg aatgtaaaca gtgtggtaaa gcctttagtt   1620

tttctagttc ctttcggatg catgaaagga ctcacactgg agagaaaccc tatgaatgta   1680

aacaatgtgg taaagccttc agttgttcca gttcctttcg aatgcatgaa aggactcaca   1740

ctggggagaa accctatgaa tgtaaacagt gtggtaaggc gtttagttgt tccagttcca   1800

ttcgaataca tgaaaggact cacactggag agaaacctta tgagtgtaaa caatgtggta   1860

aggccttcag ttgttctagt tctgttcgaa tgcatgaaag gactcacact ggagtgaaac   1920

cctatgaatg taaacaatgt gacaaagcct tcagttgctc acgttccttt cgaatccatg   1980

aacgaactca cactggagag aaaccctatg catgtcaaca atgtggtaaa gccttcaagt   2040

gttcccgttc ctttcgaata catgaaagag ttcatagtgg agagtaaccc tatgtatata   2100

agcaatatgg caaagttttc agttgtccta tttccttttt tttttttttt tttt         2154


<210>  9185
<211>  641
<212>  PRT
<213>  Homo sapiens

<400>  9185

Met Asp Ser Val Val Phe Glu Asp Val Ala Val Asn Phe Thr Gln Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Gly Pro Ser Gln Lys Lys Leu Tyr Arg Asp Val 
            20                  25                  30


Met Gln Glu Thr Phe Val Asn Leu Ala Ser Ile Gly Glu Asn Trp Glu 
        35                  40                  45


Glu Lys Asn Ile Glu Asp His Lys Asn Gln Gly Arg Lys Leu Arg Ser 
    50                  55                  60


His Met Val Glu Arg Leu Cys Glu Arg Lys Glu Gly Ser Gln Phe Gly 
65                  70                  75                  80


Glu Thr Ile Ser Gln Thr Pro Asn Pro Lys Pro Asn Lys Lys Thr Phe 
                85                  90                  95


Thr Arg Val Lys Pro Tyr Glu Cys Ser Val Cys Gly Lys Asp Tyr Met 
            100                 105                 110


Cys His Ser Ser Leu Asn Arg His Met Arg Ser His Thr Glu His Arg 
        115                 120                 125


Ser Tyr Glu Tyr His Lys Tyr Gly Glu Lys Ser Tyr Glu Cys Lys Glu 
    130                 135                 140


Cys Gly Lys Arg Phe Ser Phe Arg Ser Ser Phe Arg Ile His Glu Arg 
145                 150                 155                 160


Thr His Thr Gly Glu Lys Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala 
                165                 170                 175


Phe Ser Trp Pro Ser Ser Phe Gln Ile His Glu Arg Thr His Thr Gly 
            180                 185                 190


Glu Lys Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ile Tyr His 
        195                 200                 205


Thr Thr Phe Arg Gly His Met Arg Met His Thr Gly Glu Lys Pro Tyr 
    210                 215                 220


Lys Cys Lys Glu Cys Gly Lys Thr Phe Ser His Pro Ser Ser Phe Arg 
225                 230                 235                 240


Asn His Glu Arg Thr His Ser Gly Glu Lys Pro Tyr Glu Cys Lys Gln 
                245                 250                 255


Cys Gly Lys Ala Phe Arg Tyr Tyr Gln Thr Phe Gln Ile His Glu Arg 
            260                 265                 270


Thr His Thr Gly Glu Lys Pro Tyr Gln Cys Lys Gln Cys Gly Lys Ala 
        275                 280                 285


Leu Ser Cys Pro Thr Ser Phe Arg Ser His Glu Arg Ile His Thr Gly 
    290                 295                 300


Glu Lys Pro Tyr Lys Cys Lys Lys Cys Gly Lys Ala Phe Ser Phe Pro 
305                 310                 315                 320


Ser Ser Phe Arg Lys His Glu Arg Ile His Thr Gly Glu Lys Pro Tyr 
                325                 330                 335


Asp Cys Lys Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser Tyr Arg 
            340                 345                 350


Arg His Met Ile Met His Thr Gly Asn Gly Pro Tyr Lys Cys Lys Glu 
        355                 360                 365


Cys Gly Lys Ala Phe Asp Cys Pro Ser Ser Phe Gln Ile His Glu Arg 
    370                 375                 380


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala 
385                 390                 395                 400


Phe Ser Cys Ser Ser Ser Phe Arg Met His Glu Arg Thr His Thr Gly 
                405                 410                 415


Glu Lys Pro His Glu Cys Lys Gln Cys Gly Lys Ala Phe Ser Cys Ser 
            420                 425                 430


Ser Ser Val Arg Ile His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr 
        435                 440                 445


Glu Cys Lys Gln Cys Gly Lys Ala Phe Ser Cys Ser Ser Ser Phe Arg 
    450                 455                 460


Met His Glu Arg Ile His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln 
465                 470                 475                 480


Cys Gly Lys Ala Phe Ser Phe Ser Ser Ser Phe Arg Met His Glu Arg 
                485                 490                 495


Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala 
            500                 505                 510


Phe Ser Cys Ser Ser Ser Phe Arg Met His Glu Arg Thr His Thr Gly 
        515                 520                 525


Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys Ala Phe Ser Cys Ser 
    530                 535                 540


Ser Ser Ile Arg Ile His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr 
545                 550                 555                 560


Glu Cys Lys Gln Cys Gly Lys Ala Phe Ser Cys Ser Ser Ser Val Arg 
                565                 570                 575


Met His Glu Arg Thr His Thr Gly Val Lys Pro Tyr Glu Cys Lys Gln 
            580                 585                 590


Cys Asp Lys Ala Phe Ser Cys Ser Arg Ser Phe Arg Ile His Glu Arg 
        595                 600                 605


Thr His Thr Gly Glu Lys Pro Tyr Ala Cys Gln Gln Cys Gly Lys Ala 
    610                 615                 620


Phe Lys Cys Ser Arg Ser Phe Arg Ile His Glu Arg Val His Ser Gly 
625                 630                 635                 640


Glu 



<210>  9186
<211>  554
<212>  DNA
<213>  Homo sapiens

<400>  9186
gtctgctgtg accagctctg accaaaggag gcgtagtaag gaagccagga cacctggaac     60

ccgggatacg gactcagtgg tctttgagga tgtggctgtg aacttcaccc aggaggagtg    120

ggctttgctg ggtccctctc agaagaaact ctacagagat gtgatgcaag aaacctttgt    180

taacttggcc tctatagggg aaaactggga ggagaagaac attgaagatc acaaaaatca    240

ggggagaaag ctaagaagtc atatggtaga gaggctctgt gaaaggaaag aaggtagtca    300

gtttggagaa accatcagtc agactccaaa tcctaaacca aacaagaaaa cttttactag    360

agtaaaacca tatgaatgta gtgtgtgtgg aaaggactat atgtgtcatt catctcttaa    420

taggcacatg agatctcata ctgaacatag atcatatgaa tatcacaaat atggagagaa    480

atcatatgaa tgtaaggaat gtgggaaaag attcagcttt cgaagttcat ttcgaataca    540

tgaaagaact caca                                                      554


<210>  9187
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  9187

Met Gln Glu Thr Phe Val Asn Leu Ala Ser Ile Gly Glu Asn Trp Glu 
1               5                   10                  15


Glu Lys Asn Ile Glu Asp His Lys Asn Gln Gly Arg Lys Leu Arg Ser 
            20                  25                  30


His Met Val Glu Arg Leu Cys Glu Arg Lys Glu Gly Ser Gln Phe Gly 
        35                  40                  45


Glu Thr Ile Ser Gln Thr Pro Asn Pro Lys Pro Asn Lys Lys Thr Phe 
    50                  55                  60


Thr Arg Val Lys Pro Tyr Glu Cys Ser Val Cys Gly Lys Asp Tyr Met 
65                  70                  75                  80


Cys His Ser Ser Leu Asn Arg His Met Arg Ser His Thr Glu His Arg 
                85                  90                  95


Ser Tyr Glu Tyr His Lys Tyr Gly Glu Lys Ser Tyr Glu Cys Lys Glu 
            100                 105                 110


Cys Gly Lys Arg Phe Ser Phe Arg Ser Ser Phe Arg Ile His Glu Arg 
        115                 120                 125


Thr 



<210>  9188
<211>  399
<212>  DNA
<213>  Homo sapiens

<400>  9188
gtggcgccgc tgcagtccct gtctgctgtg accagctctg accaaaggag gcgtagtaag     60

gaagccagga cacctggaac ccgggatacg gactcagtgg tctttgagga tgtggctgtg    120

aacttcaccc aggaggagtg ggctttgctg ggtccctctc agaagaaact ctacagagat    180

gtgatgcaag aaacctttgt taacttggcc tctatagggg aaaactggga ggagaagaac    240

attgaagatc acaaaaatca ggggagaaag ctaagaagtc atatggtaga gaggctctgt    300

gaaaggaaag aaggtagtca gtttggagaa accatcagtc agactccaaa tcctaaacca    360

aacaagaaaa cttttactag agtaaaacca tatgaatgt                           399


<210>  9189
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  9189

Met Gln Glu Thr Phe Val Asn Leu Ala Ser Ile Gly Glu Asn Trp Glu 
1               5                   10                  15


Glu Lys Asn Ile Glu Asp His Lys Asn Gln Gly Arg Lys Leu Arg Ser 
            20                  25                  30


His Met Val Glu Arg Leu Cys Glu Arg Lys Glu Gly Ser Gln Phe Gly 
        35                  40                  45


Glu Thr Ile Ser Gln Thr Pro Asn Pro Lys Pro Asn Lys Lys Thr Phe 
    50                  55                  60


Thr Arg Val Lys Pro Tyr Glu 
65                  70


<210>  9190
<211>  2934
<212>  DNA
<213>  Homo sapiens

<400>  9190
aggaactctg caagggggac aggggcaatg ttcaacaact ccgcggggtc ttcctgtttc     60

gtgtccgctg cgtttgggtt ccggtctccg cttctccagt ggccccggtg gctccaccgc    120

agcgtctggc gcgctgggac ctgcacaggc cggagagagc cgtaggcagg accccgggac    180

accctggaag ccaggaaatg gactcagtgg cctctgagga tgtggctgtg aacttcacac    240

ttgaggagtg ggctttgctg gatccttccc agaagaaact ctacagagat gtgatgcggg    300

aaacctttag aaacctggcc tgtgtaggaa aaaaatggga agaccagagc attgaagatt    360

ggtacaaaaa tcaggggaga attttaagaa atcatatgga agagggactc agtgaaagta    420

aagaatatga tcaatgtgga gaagccttca gtcagattct caatcttaat ctgaacaaga    480

aaattcctac tatagtaaga ccatgtgaat gtagtttgtg tgggaaagtc ttcatgcatc    540

attcatccct tagtaggcac atcagatctc accttggaca caaaccatat gactatcagg    600

aatatggaga gaaaccatat aaatgtaagc agtgtgggaa agccttcagt tcttgtcaat    660

cctttcgaag acatgaaaga actcacactg gtgagaaacc ctatgcatgt ccggaatgtg    720

ggaaagcctt catttctctc ccaagtgttc gaagacacat gattaagcac actggagatg    780

gaccatataa atgtcaggaa tgtgggaaag cctttgatcg cccaagttta tttcagatac    840

atgaaagaac tcacactgga gagaaaccct atgaatgtca ggaatgtgca aaagctttca    900

tttctcttcc aagttttcaa agacacatga ttaggcacac tggagatgga ccttataaat    960

gtcaggaatg tggaaaagcc tttgaccgcc ccagtttatt tcgaatacat gaaagaactc   1020

atactggaga gaaaccccat gaatgtaaac agtgtgggaa ggccttcatt tctttcacaa   1080

attttcaaag tcatatgatt aggcacactg gggatggacc ttataaatgt aaagtatgtg   1140

ggagagcctt tatttttccc agttatgttc gaaagcatga aagaactcat actggggaga   1200

aaccctatga atgtaataaa tgtggtaaaa ccttcagttc ttccagtaat gttcgaacac   1260

atgaaaggac tcacactgga gagaagccct atgaatgtaa ggaatgcggg aaagccttca   1320

tttctctccc aagtgtccga agacacatga taaagcacac tggagatgga ccttataaat   1380

gtcaggtatg tggtagagcc tttgactgtc ccagttcatt tcaaatacac gaaagaactc   1440

acactggaga gaaaccctat gaatgtcagg tatgtgggaa agccttcatt tctcttaaaa   1500

ggattagaaa acatatgata ctgcacactg gagatggacc ttataaatgt caggtatgtg   1560

gtaaagcctt tgactgtcct agttctgtcc gaacacatga aagaactcat actggagaaa   1620

aaccctatga atgtaaagaa tgtgggaaag cattcaatta tgccagttcc attagaatac   1680

atgaaagaac tcataccgga gaaaaaccct atgaatgtaa gcaatgtgga aaaacgttca   1740

gttattccag ttcctttcaa agacatgaaa gagctcataa tggagataaa ccttacgtaa   1800

agaatgtggg aaagctttca tttatcacac aaccttcgaa tacctgtgaa aatgaatagt   1860

ggaggacagg tctacaagta tctacatatc taaagaatat ggaaagtctt cagtttgctt   1920

tctgggtttc agacttgttt gggagctcac ccctttctcc tgtttctcac ttttggaata   1980

ggaatctcta tcctgtgcct gtctcatatt ttggaaatac atgactagtt tggttttcac   2040

cggttcggag ctgaagaaga attttgcctc agcatgaatt gagtctcatc catatctgag   2100

tgatgtgata ttgagatgac actttggagt ttgagtttaa acattaggct tcatgctgga   2160

attaactgag acttttgagg cctttgggat gagatgaata tattttacat gtgatgacat   2220

ggattttggg ggccagaggt gtaatgtttt ggctgagtgt atgccacctc agattcatat   2280

gttgaaacct tacccccgtg ccccccctct cccccacaat gtgatggtat ttggaggccc   2340

tgtctctggt ggtttttagg attggaggac atcatgaaga tggaggcctt gtaattggga   2400

ttagtttcct gataggaatc cctagagagc tagctttgcc cttcaccatg agagggtgca   2460

gtgagaagat agctatcttt gaaccgggaa gcaggccctt accagacatg gactatgcca   2520

gtgccttgat attggacttc ccagcctccc aaaccatgag aaataaatgt ttgttgatta   2580

attaagcttt ccaatttatg gtattttgtt ttagcaaccc aagctaagac acaatccaat   2640

tttaaaatgg aggaaaggac ttgaatagac atttctccaa agaagatacc cagatggcca   2700

ataagcacgt aacaatgctc gacatcttta gtcattaggg aaatacaaat caaactcaag   2760

acatacatag catctcatta ggattagtag tatcaaagat ggaaaacaag aaatactgtc   2820

aaggatgtgg aatgttggag aacattgtgc actatcactg ggaatgtaca gtggtataag   2880

cctgctgaaa acagtatggc agatccccag attaaaatat agaaataaca tatg         2934


<210>  9191
<211>  553
<212>  PRT
<213>  Homo sapiens

<400>  9191

Met Asp Ser Val Ala Ser Glu Asp Val Ala Val Asn Phe Thr Leu Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Asp Pro Ser Gln Lys Lys Leu Tyr Arg Asp Val 
            20                  25                  30


Met Arg Glu Thr Phe Arg Asn Leu Ala Cys Val Gly Lys Lys Trp Glu 
        35                  40                  45


Asp Gln Ser Ile Glu Asp Trp Tyr Lys Asn Gln Gly Arg Ile Leu Arg 
    50                  55                  60


Asn His Met Glu Glu Gly Leu Ser Glu Ser Lys Glu Tyr Asp Gln Cys 
65                  70                  75                  80


Gly Glu Ala Phe Ser Gln Ile Leu Asn Leu Asn Leu Asn Lys Lys Ile 
                85                  90                  95


Pro Thr Ile Val Arg Pro Cys Glu Cys Ser Leu Cys Gly Lys Val Phe 
            100                 105                 110


Met His His Ser Ser Leu Ser Arg His Ile Arg Ser His Leu Gly His 
        115                 120                 125


Lys Pro Tyr Asp Tyr Gln Glu Tyr Gly Glu Lys Pro Tyr Lys Cys Lys 
    130                 135                 140


Gln Cys Gly Lys Ala Phe Ser Ser Cys Gln Ser Phe Arg Arg His Glu 
145                 150                 155                 160


Arg Thr His Thr Gly Glu Lys Pro Tyr Ala Cys Pro Glu Cys Gly Lys 
                165                 170                 175


Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met Ile Lys His Thr 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Gln Glu Cys Gly Lys Ala Phe Asp Arg 
        195                 200                 205


Pro Ser Leu Phe Gln Ile His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Gln Glu Cys Ala Lys Ala Phe Ile Ser Leu Pro Ser Phe 
225                 230                 235                 240


Gln Arg His Met Ile Arg His Thr Gly Asp Gly Pro Tyr Lys Cys Gln 
                245                 250                 255


Glu Cys Gly Lys Ala Phe Asp Arg Pro Ser Leu Phe Arg Ile His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro His Glu Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ile Ser Phe Thr Asn Phe Gln Ser His Met Ile Arg His Thr 
    290                 295                 300


Gly Asp Gly Pro Tyr Lys Cys Lys Val Cys Gly Arg Ala Phe Ile Phe 
305                 310                 315                 320


Pro Ser Tyr Val Arg Lys His Glu Arg Thr His Thr Gly Glu Lys Pro 
                325                 330                 335


Tyr Glu Cys Asn Lys Cys Gly Lys Thr Phe Ser Ser Ser Ser Asn Val 
            340                 345                 350


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
        355                 360                 365


Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met 
    370                 375                 380


Ile Lys His Thr Gly Asp Gly Pro Tyr Lys Cys Gln Val Cys Gly Arg 
385                 390                 395                 400


Ala Phe Asp Cys Pro Ser Ser Phe Gln Ile His Glu Arg Thr His Thr 
                405                 410                 415


Gly Glu Lys Pro Tyr Glu Cys Gln Val Cys Gly Lys Ala Phe Ile Ser 
            420                 425                 430


Leu Lys Arg Ile Arg Lys His Met Ile Leu His Thr Gly Asp Gly Pro 
        435                 440                 445


Tyr Lys Cys Gln Val Cys Gly Lys Ala Phe Asp Cys Pro Ser Ser Val 
    450                 455                 460


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
465                 470                 475                 480


Glu Cys Gly Lys Ala Phe Asn Tyr Ala Ser Ser Ile Arg Ile His Glu 
                485                 490                 495


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys 
            500                 505                 510


Thr Phe Ser Tyr Ser Ser Ser Phe Gln Arg His Glu Arg Ala His Asn 
        515                 520                 525


Gly Asp Lys Pro Tyr Val Lys Asn Val Gly Lys Leu Ser Phe Ile Thr 
    530                 535                 540


Gln Pro Ser Asn Thr Cys Glu Asn Glu 
545                 550


<210>  9192
<211>  2583
<212>  DNA
<213>  Homo sapiens

<400>  9192
aggaactctg caagggggac aggggcaatg ttcaacaact ccgcggggtc ttcctgtttc     60

gtgtccgctg cgtttgggtt ccggtctccg cttctccagt ggccccggtg gctccaccgc    120

agcgtctggc gcgctgggac ctgcacaggc cggagagagc cgtaggcagg accccgggac    180

accctggaag ccaggaaatg gactcagtgg cctctgagga tgtggctgtg aacttcacac    240

ttgaggagtg ggctttgctg gatccttccc agaagaaact ctacagagat gtgatgcggg    300

aaacctttag aaacctggcc tgtgtaggaa aaaaatggga agaccagagc attgaagatt    360

ggtacaaaaa tcaggggaga attttaagaa atcatatgga agagggactc agtgaaagta    420

aagaatatga tcaatgtgga gaagccttca gtcagattct caatcttaat ctgaacaaga    480

aaattcctac tatagtaaga ccatgtgaat gtagtttgtg tgggaaagtc ttcatgcatc    540

attcatccct tagtaggcac atcagatctc accttggaca caaaccatat gactatcagg    600

aatatggaga gaaaccatat aaatgtaagc agtgtgggaa agccttcagt tcttgtcaat    660

cctttcgaag acatgaaaga actcacactg gtgagaaacc ctatgcatgt ccggaatgtg    720

ggaaagcctt catttctctc ccaagtgttc gaagacacat gattaagcac actggagatg    780

gaccatataa atgtcaggaa tgtgggaaag cctttgatcg cccaagttta tttcagatac    840

atgaaagaac tcacactgga gagaaaccct atgaatgtca ggaatgtgca aaagctttca    900

tttctcttcc aagttttcaa agacacatga ttaggcacac tggagatgga ccttataaat    960

gtcaggaatg tggaaaagcc tttgaccgcc ccagtttatt tcgaatacat gaaagaactc   1020

atactggaga gaaaccccat gaatgtaaac agtgtgggaa ggccttcatt tctttcacaa   1080

attttcaaag tcatatgatt aggcacactg gggatggacc ttataaatgt aaagtatgtg   1140

ggagagcctt tatttttccc agttatgttc gaaagcatga aagaactcat actggggaga   1200

aaccctatga atgtaataaa tgtggtaaaa ccttcagttc ttccagtaat gttcgaacac   1260

atgaaaggac tcacactgga gagaagccct atgaatgtaa ggaatgcggg aaagccttca   1320

tttctctccc aagtgtccga agacacatga taaagcacac tggagatgga ccttataaat   1380

gtcaggtatg tggtagagcc tttgactgtc ccagttcatt tcaaatacac gaaagaactc   1440

acactggaga gaaaccctat gaatgtcagg tatgtgggaa agccttcatt tctcttaaaa   1500

ggattagaaa acatatgata ctgcacactg gagatggacc ttataaatgt caggtatgtg   1560

gtaaagcctt tgactgtcct agttctgtcc gaacacatga aagaactcat actggagaaa   1620

aaccctatga atgtaaagaa tgtgggaaag cattcaatta tgccagttcc attagaatac   1680

atgaaagaac tcataccgga gaaaaaccct atgaatgtaa gcaatgtgga aaaacgttca   1740

gttattccag ttcctttcaa agacatgaaa gagctcataa tggagataaa ccttacgtaa   1800

agaatgtggg aaagctttca tttatcacac aaccttcgaa tacctgtgaa aatgaatagt   1860

ggaggacagg tctacaagta tctacatatc taaagaatat ggaaagtctt cagtttgctt   1920

tctgggtttc agacttgttt gggagctcac ccctttctcc tgtttctcac ttttggaata   1980

ggaatctcta tcctgtgcct gtctcatatt ttggaaatac atgactagtt tggttttcac   2040

cggttcggag ctgaagaaga attttgcctc agcatgaatt gagtctcatc catatctgag   2100

tgatgtgata ttgagatgac actttggagt ttgagtttaa acattaggct tcatgctgga   2160

attaactgag acttttgagg cctttgggat gagatgaata tattttacat gtgatgacat   2220

ggattttggg ggccagaggt gtaatgtttt ggctgagtgt atgccacctc agattcatat   2280

gttgaaacct tacccccgtg ccccccctct cccccacaat gtgatggtat ttggaggccc   2340

tgtctctggt ggtttttagg attggaggac atcatgaaga tggaggcctt gtaattggga   2400

ttagtttcct gataggaatc cctagagagc tagctttgcc cttcaccatg agagggtgca   2460

gtgagaagat agctatcttt gaaccgggaa gcaggccctt accagacatg gactatgcca   2520

gtgccttgat attggacttc ccagcctccc aaaccatgag aaataaatgt ttgttgatta   2580

att                                                                 2583


<210>  9193
<211>  553
<212>  PRT
<213>  Homo sapiens

<400>  9193

Met Asp Ser Val Ala Ser Glu Asp Val Ala Val Asn Phe Thr Leu Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Asp Pro Ser Gln Lys Lys Leu Tyr Arg Asp Val 
            20                  25                  30


Met Arg Glu Thr Phe Arg Asn Leu Ala Cys Val Gly Lys Lys Trp Glu 
        35                  40                  45


Asp Gln Ser Ile Glu Asp Trp Tyr Lys Asn Gln Gly Arg Ile Leu Arg 
    50                  55                  60


Asn His Met Glu Glu Gly Leu Ser Glu Ser Lys Glu Tyr Asp Gln Cys 
65                  70                  75                  80


Gly Glu Ala Phe Ser Gln Ile Leu Asn Leu Asn Leu Asn Lys Lys Ile 
                85                  90                  95


Pro Thr Ile Val Arg Pro Cys Glu Cys Ser Leu Cys Gly Lys Val Phe 
            100                 105                 110


Met His His Ser Ser Leu Ser Arg His Ile Arg Ser His Leu Gly His 
        115                 120                 125


Lys Pro Tyr Asp Tyr Gln Glu Tyr Gly Glu Lys Pro Tyr Lys Cys Lys 
    130                 135                 140


Gln Cys Gly Lys Ala Phe Ser Ser Cys Gln Ser Phe Arg Arg His Glu 
145                 150                 155                 160


Arg Thr His Thr Gly Glu Lys Pro Tyr Ala Cys Pro Glu Cys Gly Lys 
                165                 170                 175


Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met Ile Lys His Thr 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Gln Glu Cys Gly Lys Ala Phe Asp Arg 
        195                 200                 205


Pro Ser Leu Phe Gln Ile His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Gln Glu Cys Ala Lys Ala Phe Ile Ser Leu Pro Ser Phe 
225                 230                 235                 240


Gln Arg His Met Ile Arg His Thr Gly Asp Gly Pro Tyr Lys Cys Gln 
                245                 250                 255


Glu Cys Gly Lys Ala Phe Asp Arg Pro Ser Leu Phe Arg Ile His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro His Glu Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ile Ser Phe Thr Asn Phe Gln Ser His Met Ile Arg His Thr 
    290                 295                 300


Gly Asp Gly Pro Tyr Lys Cys Lys Val Cys Gly Arg Ala Phe Ile Phe 
305                 310                 315                 320


Pro Ser Tyr Val Arg Lys His Glu Arg Thr His Thr Gly Glu Lys Pro 
                325                 330                 335


Tyr Glu Cys Asn Lys Cys Gly Lys Thr Phe Ser Ser Ser Ser Asn Val 
            340                 345                 350


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
        355                 360                 365


Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met 
    370                 375                 380


Ile Lys His Thr Gly Asp Gly Pro Tyr Lys Cys Gln Val Cys Gly Arg 
385                 390                 395                 400


Ala Phe Asp Cys Pro Ser Ser Phe Gln Ile His Glu Arg Thr His Thr 
                405                 410                 415


Gly Glu Lys Pro Tyr Glu Cys Gln Val Cys Gly Lys Ala Phe Ile Ser 
            420                 425                 430


Leu Lys Arg Ile Arg Lys His Met Ile Leu His Thr Gly Asp Gly Pro 
        435                 440                 445


Tyr Lys Cys Gln Val Cys Gly Lys Ala Phe Asp Cys Pro Ser Ser Val 
    450                 455                 460


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
465                 470                 475                 480


Glu Cys Gly Lys Ala Phe Asn Tyr Ala Ser Ser Ile Arg Ile His Glu 
                485                 490                 495


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys 
            500                 505                 510


Thr Phe Ser Tyr Ser Ser Ser Phe Gln Arg His Glu Arg Ala His Asn 
        515                 520                 525


Gly Asp Lys Pro Tyr Val Lys Asn Val Gly Lys Leu Ser Phe Ile Thr 
    530                 535                 540


Gln Pro Ser Asn Thr Cys Glu Asn Glu 
545                 550


<210>  9194
<211>  6528
<212>  DNA
<213>  Homo sapiens

<400>  9194
cttaatacga acctggaaac tcctactgga ttaaaaccat gtgactgcag tgtgtgtggg     60

gaagtcttca tgcatcaggt ctcccttaat aggcacatga gatctcacac tgaacagaaa    120

ccaaatgagt gtcacgaata tggagagaag ccacataaat gcaaagaatg tgggaaaacc    180

ttcactcgca gctccagtat tcgaacccat gaaagaattc acactggaga gaaaccctat    240

gaatgtaagg aatgtggcaa agccttcgca tttctctttt cctttcgaaa ccatataaga    300

attcatactg gagagacacc ctatgaatgt aaggaatgtg ggaaggcatt cagatatctc    360

actgctcttc ggcgccatga aaaaaatcac actggagaga aaccctacaa atgtaaacag    420

tgtggaaaag cctttatata ttaccagcct tttctaaccc acgaaaggac tcacactgga    480

gagaaacctt atgaatgtaa gcaatgtggg aaagccttca gttgtcccac gtacttacgg    540

agtcatgaga aaactcatac tggagagaaa ccttttgtat gtagggaatg tgggagagcc    600

ttcttttctc actcaagcct tcgaaaacac gtgaaaaccc acaccggagt tcaaccttat    660

acatgtaaga aatgtgggga agccttcaag tcatctagtt cctgtgaagt gcacgaaaga    720

actcattttg gagaaaaacc ctatgaatgt aaacaatgtg gtaaagcctt caattcttca    780

agttaccttc agttgcacga aagagttcac actggcgaga aaacttacga atgtaaagaa    840

tgtggtaaag cctttcttta ttccactcac tttcgaatcc atgaaagaac ccatactaga    900

gagaaaccct atgaatgcaa acagtgtggt cgggtcttca tttacttcag tcaccttcga    960

aggcacgaaa gaagtcacac tggagtgaaa ccatgtgagt gtaagcagtg tggcaaagct   1020

ttcacttgtt taaattccct gaaagtacac aaaagaattc atactggaga aagacccttt   1080

cagtgtagac aatgtggtaa agccttcagt tactcaaagt ctttgcacgt gcacgaaagg   1140

actcatagta gacagaagcc ctaagaaagt aaagtgtggt aatgctgtca gttgtattag   1200

ttccttttgg atgtatgaga gtacttacgc tggagagaaa ttcaaggaat gtaaacggtg   1260

tgattaagcc ttcagttgtc ctaattccct ttgaagacgt gactcatgcg gcaatgaaat   1320

atttaacaaa tgggggagga acttgcactc tcctgcggga ttgcagatat gtgaatggac   1380

tccatggaca gaaaagctac gaatgtatgg agtgtaggaa agccttcact tcacgtaatc   1440

ttttaaagac acctgagaat atatactgga gagaaactat aaagaaaatt ctatatccat   1500

cccatctttt gtggggtttg ttttttgttt ttgtttttgt tgagatgtaa ttttgctctt   1560

gttgcccagg ctggagtgca gtggtgcgat cgcggctcac cgcaacctcc gcctcccgga   1620

ttcaagcaat tctcctgccg cagcctccca agaagctggg attacaggca tgcgccacca   1680

cgcctggcta attttgtaat tttagtagag atggggtttc tccatgttgg tcaggctggt   1740

ctcaaactcc tgacctcagg tgatctgcct gcctcggcct cccaaagtgc tgggattaca   1800

ggtgtgagcc acagcaccca accttttttt ccccgccgca ccccaagatg gtgtctcact   1860

ctgttgcccc aggctggagt gcagtggtgt gatcctggct cactgtaacc tctgggttca   1920

agcaattctt ctgcctcagc cttccaagta gctgggatta caagtgccca ccaccatgcc   1980

cagctaattt ttatattttt agtagagaca gtgtttcacc atgttgacca ggctgatctt   2040

aaactcttga cctcaaatga tccacccacc ttggcctccc aaattgttcg ttttactttt   2100

tttttttttt ttttttgagc tggagtctta ctctgttgcc taggctggag tgaaagtggc   2160

gcaacctctg cctcccaggt caaagcaatc ctgcctcagg ccccctagta gctggcatta   2220

caggcacatg ccaccacgcc caactaattt ttatattttt agtagagacg gggtttcacc   2280

atgttggcca ggctggtctt gaactcctga cctcaggtaa tccacctgcc ttggcctccc   2340

aaagtgctgg gattacaggc gtgagccacc acacccggcc cccagttctt tttttttttt   2400

tttgagacgg agtccttgcc caggctggag tgcagtggcg cgatctcagc tcactgcaag   2460

ctccgcctcc tgggttcacg ccattctcct gcctcagcct cccgagtagc tgggactaca   2520

ggcgcccgcc accacgcccg gctcattttt tgtattttta gtggagacgg ggtttcaccg   2580

tgttagccag gatagtcttg atctcctgac ctcgtgatcc gccctcctcg gcctcccaaa   2640

gtgctgggat tataggcgtg agccaccgcg cccggcctcc agttcatttt aaaaccatga   2700

aaccacccac actggagagc caccttctta aatgtaagca atatgggaac atcttcaatg   2760

acatctgcaa ccattgtcga gattcttcgt aggaagaatt aaaggaatgg ggaagaagga   2820

cttgggcccc agcaggcctt ttgtggcatc cagtcagaag ttaggaaaca ccctctaggg   2880

cagtgcctgc cctcagctct cacacatgac tggagagaag tgagaagact cccagaatct   2940

gccttttaag tttccatcag tgtcctcggg tcagactgtg ggaatgctgt acttctaaga   3000

caaaggttcg catcttacag tttttcccca agtgggatct gcctatgcac atcctaattc   3060

acagacattg tcagcattgc attattccag ggctgttttg aggtcatctc cagctccatt   3120

tcccatctca aacctacact ttggacactt gtttaaacat tcacatctga atttctctgt   3180

ggcaaccgca ggtggctctg aggtgagaga ctgaagaagc agagcctgta tcatgggaca   3240

cacacccctt gaccacacag catccactct cctgcggtta ccagccctgc accaaccacc   3300

acagtcagaa taatctcaaa actgctagtg gagtcacaga cacactctgc catgtcttag   3360

ctgtaggaca ctcagaattc ttacctcccc taacttgctt tccctgtttt ctggcacatt   3420

ctaccctgag atattcagcg gcatatgcac tgatgatgct ccggccttct cacgtcagtg   3480

catgtcacat gcatcctgct ccaggactgg tttcctagcc tcccgctaag actagcactt   3540

agctcttctt ggaaaaggac ccaccctgca gcgctccagc tctgttgtgt atgggaggtg   3600

ctggtgtcag ggttcacaag ccatggaact accttgcttc acatcacaag gcaaggtgaa   3660

ctcaactccc aataaactgc ttgctggagc ctccgaattc tccgttttct gaattgcata   3720

ggcacgatag gggtcgggtc tgtcctttgt tggagtcagt cccccctttt cttagcaagt   3780

cagtgtgttt tagaagggag gtggcagcat tgagggaaac caggtcacca tccaccctcg   3840

taacaacagt ctccctgggt gggtcccaga agtgatcttt gtgtcgctcg ggtcggaact   3900

ctttaggcct ctggcctcca ccctccccca acagcaggga tgggtcaggt ggcagcatcc   3960

aaaaccacgg tgaagatact agggtccaga ggccgactgg agcaaggttt gctggcagat   4020

gaggcctcag tggaagtgac ggctactgtg gagatgcagt ggaggacctg gtggctgagc   4080

caggagatgc acaccttcgc ttctctcacc aggaacattc gcttctctca ccaggaacat   4140

ttatggactc agtggcctct gaggatgtgg ctgtgaactt cacacttgag gagtgggctt   4200

tgctggatcc ttcccagaag aaactctaca gagatgtgat gcgggaaacc tttagaaacc   4260

tggcctgtgt aggaaaaaaa tgggaagacc agagcattga agattggtac aaaaatcagg   4320

ggagaatttt aagaaatcat atggaagagg gactcagtga aagtaaagaa tatgatcaat   4380

gtggagaagc cttcagtcag attctcaatc ttaatctgaa caagaaaatt cctactatag   4440

taagaccatg tgaatgtagt ttgtgtggga aagtcttcat gcatcattca tcccttagta   4500

ggcacatcag atctcacctt ggacacaaac catatgacta tcaggaatat ggagagaaac   4560

catataaatg taagcagtgt gggaaagcct tcagttcttg tcaatccttt cgaagacatg   4620

aaagaactca cactggtgag aaaccctatg catgtccgga atgtgggaaa gccttcattt   4680

ctctcccaag tgttcgaaga cacatgatta agcacactgg agatggacca tataaatgtc   4740

aggaatgtgg gaaagccttt gatcgcccaa gtttatttca gatacatgaa agaactcaca   4800

ctggagagaa accctatgaa tgtcaggaat gtgcaaaagc tttcatttct cttccaagtt   4860

ttcaaagaca catgattagg cacactggag atggacctta taaatgtcag gaatgtggaa   4920

aagcctttga ccgccccagt ttatttcgaa tacatgaaag aactcatact ggagagaaac   4980

cccatgaatg taaacagtgt gggaaggcct tcatttcttt cacaaatttt caaagtcata   5040

tgattaggca cactggggat ggaccttata aatgtaaagt atgtgggaga gcctttattt   5100

ttcccagtta tgttcgaaag catgaaagaa ctcatactgg ggagaaaccc tatgaatgta   5160

ataaatgtgg taaaaccttc agttcttcca gtaatgttcg aacacatgaa aggactcaca   5220

ctggagagaa gccctatgaa tgtaaggaat gcgggaaagc cttcatttct ctcccaagtg   5280

tccgaagaca catgataaag cacactggag atggacctta taaatgtcag gtatgtggta   5340

gagcctttga ctgtcccagt tcatttcaaa tacacgaaag aactcacact ggagagaaac   5400

cctatgaatg tcaggtatgt gggaaagcct tcatttctct taaaaggatt agaaaacata   5460

tgatactgca cactggagat ggaccttata aatgtcaggt atgtggtaaa gcctttgact   5520

gtcctagttc tgtccgaaca catgaaagaa ctcatactgg agaaaaaccc tatgaatgta   5580

aagaatgtgg gaaagcattc aattatgcca gttccattag aatacatgaa agaactcata   5640

ccggagaaaa accctatgaa tgtaagcaat gtggaaaaac gttcagttat tccagttcct   5700

ttcaaagaca tgaaagagct cataatggag ataaacctta cgtaaagaat gtgggaaagc   5760

tttcatttat cacacaacct tcgaatacct gtgaaaatga atagtggagg acaggtctac   5820

aagtatctac atatctaaag aatatggaaa gtcttcagtt tgctttctgg gtttcagact   5880

tgtttgggag ctcacccctt tctcctgttt ctcacttttg gaataggaat ctctatcctg   5940

tgcctgtctc atattttgga aatacatgac tagtttggtt ttcaccggtt cggagctgaa   6000

gaagaatttt gcctcagcat gaattgagtc tcatccatat ctgagtgatg tgatattgag   6060

atgacacttt ggagtttgag tttaaacatt aggcttcatg ctggaattaa ctgagacttt   6120

tgaggccttt gggatgagat gaatatattt tacatgtgat gacatggatt ttgggggcca   6180

gaggtgtaat gttttggctg agtgtatgcc acctcagatt catatgttga aaccttaccc   6240

ccgtgccccc cctctccccc acaatgtgat ggtatttgga ggccctgtct ctggtggttt   6300

ttaggattgg aggacatcat gaagatggag gccttgtaat tgggattagt ttcctgatag   6360

gaatccctag agagctagct ttgcccttca ccatgagagg gtgcagtgag aagatagcta   6420

tctttgaacc gggaagcagg cccttaccag acatggacta tgccagtgcc ttgatattgg   6480

acttcccagc ctcccaaacc atgagaaata aatgtttgtt gattaatt                6528


<210>  9195
<211>  553
<212>  PRT
<213>  Homo sapiens

<400>  9195

Met Asp Ser Val Ala Ser Glu Asp Val Ala Val Asn Phe Thr Leu Glu 
1               5                   10                  15


Glu Trp Ala Leu Leu Asp Pro Ser Gln Lys Lys Leu Tyr Arg Asp Val 
            20                  25                  30


Met Arg Glu Thr Phe Arg Asn Leu Ala Cys Val Gly Lys Lys Trp Glu 
        35                  40                  45


Asp Gln Ser Ile Glu Asp Trp Tyr Lys Asn Gln Gly Arg Ile Leu Arg 
    50                  55                  60


Asn His Met Glu Glu Gly Leu Ser Glu Ser Lys Glu Tyr Asp Gln Cys 
65                  70                  75                  80


Gly Glu Ala Phe Ser Gln Ile Leu Asn Leu Asn Leu Asn Lys Lys Ile 
                85                  90                  95


Pro Thr Ile Val Arg Pro Cys Glu Cys Ser Leu Cys Gly Lys Val Phe 
            100                 105                 110


Met His His Ser Ser Leu Ser Arg His Ile Arg Ser His Leu Gly His 
        115                 120                 125


Lys Pro Tyr Asp Tyr Gln Glu Tyr Gly Glu Lys Pro Tyr Lys Cys Lys 
    130                 135                 140


Gln Cys Gly Lys Ala Phe Ser Ser Cys Gln Ser Phe Arg Arg His Glu 
145                 150                 155                 160


Arg Thr His Thr Gly Glu Lys Pro Tyr Ala Cys Pro Glu Cys Gly Lys 
                165                 170                 175


Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met Ile Lys His Thr 
            180                 185                 190


Gly Asp Gly Pro Tyr Lys Cys Gln Glu Cys Gly Lys Ala Phe Asp Arg 
        195                 200                 205


Pro Ser Leu Phe Gln Ile His Glu Arg Thr His Thr Gly Glu Lys Pro 
    210                 215                 220


Tyr Glu Cys Gln Glu Cys Ala Lys Ala Phe Ile Ser Leu Pro Ser Phe 
225                 230                 235                 240


Gln Arg His Met Ile Arg His Thr Gly Asp Gly Pro Tyr Lys Cys Gln 
                245                 250                 255


Glu Cys Gly Lys Ala Phe Asp Arg Pro Ser Leu Phe Arg Ile His Glu 
            260                 265                 270


Arg Thr His Thr Gly Glu Lys Pro His Glu Cys Lys Gln Cys Gly Lys 
        275                 280                 285


Ala Phe Ile Ser Phe Thr Asn Phe Gln Ser His Met Ile Arg His Thr 
    290                 295                 300


Gly Asp Gly Pro Tyr Lys Cys Lys Val Cys Gly Arg Ala Phe Ile Phe 
305                 310                 315                 320


Pro Ser Tyr Val Arg Lys His Glu Arg Thr His Thr Gly Glu Lys Pro 
                325                 330                 335


Tyr Glu Cys Asn Lys Cys Gly Lys Thr Phe Ser Ser Ser Ser Asn Val 
            340                 345                 350


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
        355                 360                 365


Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His Met 
    370                 375                 380


Ile Lys His Thr Gly Asp Gly Pro Tyr Lys Cys Gln Val Cys Gly Arg 
385                 390                 395                 400


Ala Phe Asp Cys Pro Ser Ser Phe Gln Ile His Glu Arg Thr His Thr 
                405                 410                 415


Gly Glu Lys Pro Tyr Glu Cys Gln Val Cys Gly Lys Ala Phe Ile Ser 
            420                 425                 430


Leu Lys Arg Ile Arg Lys His Met Ile Leu His Thr Gly Asp Gly Pro 
        435                 440                 445


Tyr Lys Cys Gln Val Cys Gly Lys Ala Phe Asp Cys Pro Ser Ser Val 
    450                 455                 460


Arg Thr His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys 
465                 470                 475                 480


Glu Cys Gly Lys Ala Phe Asn Tyr Ala Ser Ser Ile Arg Ile His Glu 
                485                 490                 495


Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Lys Gln Cys Gly Lys 
            500                 505                 510


Thr Phe Ser Tyr Ser Ser Ser Phe Gln Arg His Glu Arg Ala His Asn 
        515                 520                 525


Gly Asp Lys Pro Tyr Val Lys Asn Val Gly Lys Leu Ser Phe Ile Thr 
    530                 535                 540


Gln Pro Ser Asn Thr Cys Glu Asn Glu 
545                 550


<210>  9196
<211>  2707
<212>  DNA
<213>  Homo sapiens

<400>  9196
gtccgctgcg tttgggttcc ggtctccgct tctccagtgg ccccggtggc tccaccgcag     60

cgtctggcgc gctgggacct gcacaggccg gagagagccg taggcaggac cccgggacac    120

cctggaagcc aggaaatgac agagtttcgc tctgtcgccc aggctggagt gcagtgggaa    180

gatctcagct cactgcaacc ttcgccttcc gggttcaagc aattctcctg cctcagcctc    240

ctgagtaact gggattacag gcatgcgccg ccacgaccgg ctactttttg tatttttggt    300

agaaactggg tttctccatg ttggccagga ctcagtggcc tctgaggatg tggctgtgaa    360

cttcacactt gaggagtggg ctttgctgga tccttcccag aagaaactct acagagatgt    420

gatgcgggaa acctttagaa acctggcctg tgtaggaaaa aaatgggaag accagagcat    480

tgaagattgg tacaaaaatc aggggagaat tttaagaaat catatggaag agggactcag    540

tgaaagtaaa gaatatgatc aatgtggaga agccttcagt cagattctca atcttaatct    600

gaacaagaaa attcctacta tagtaagacc atgtgaatgt agtttgtgtg ggaaagtctt    660

catgcatcat tcatccctta gtaggcacat cagatctcac cttggacaca aaccatatga    720

ctatcaggaa tatggagaga aaccatataa atgtaagcag tgtgggaaag ccttcagttc    780

ttgtcaatcc tttcgaagac atgaaagaac tcacactggt gagaaaccct atgcatgtcc    840

ggaatgtggg aaagccttca tttctctccc aagtgttcga agacacatga ttaagcacac    900

tggagatgga ccatataaat gtcaggaatg tgggaaagcc tttgatcgcc caagtttatt    960

tcagatacat gaaagaactc acactggaga gaaaccctat gaatgtcagg aatgtgcaaa   1020

agctttcatt tctcttccaa gttttcaaag acacatgatt aggcacactg gagatggacc   1080

ttataaatgt caggaatgtg gaaaagcctt tgaccgcccc agtttatttc gaatacatga   1140

aagaactcat actggagaga aaccccatga atgtaaacag tgtgggaagg ccttcatttc   1200

tttcacaaat tttcaaagtc atatgattag gcacactggg gatggacctt ataaatgtaa   1260

agtatgtggg agagccttta tttttcccag ttatgttcga aagcatgaaa gaactcatac   1320

tggggagaaa ccctatgaat gtaataaatg tggtaaaacc ttcagttctt ccagtaatgt   1380

tcgaacacat gaaaggactc acactggaga gaagccctat gaatgtaagg aatgcgggaa   1440

agccttcatt tctctcccaa gtgtccgaag acacatgata aagcacactg gagatggacc   1500

ttataaatgt caggtatgtg gtagagcctt tgactgtccc agttcatttc aaatacacga   1560

aagaactcac actggagaga aaccctatga atgtcaggta tgtgggaaag ccttcatttc   1620

tcttaaaagg attagaaaac atatgatact gcacactgga gatggacctt ataaatgtca   1680

ggtatgtggt aaagcctttg actgtcctag ttctgtccga acacatgaaa gaactcatac   1740

tggagaaaaa ccctatgaat gtaaagaatg tgggaaagca ttcaattatg ccagttccat   1800

tagaatacat gaaagaactc ataccggaga aaaaccctat gaatgtaagc aatgtggaaa   1860

aacgttcagt tattccagtt cctttcaaag acatgaaaga gctcataatg gagataaacc   1920

ttacgtaaag aatgtgggaa agctttcatt tatcacacaa ccttcgaata cctgtgaaaa   1980

tgaatagtgg aggacaggtc tacaagtatc tacatatcta aagaatatgg aaagtcttca   2040

gtttgctttc tgggtttcag acttgtttgg gagctcaccc ctttctcctg tttctcactt   2100

ttggaatagg aatctctatc ctgtgcctgt ctcatatttt ggaaatacat gactagtttg   2160

gttttcaccg gttcggagct gaagaagaat tttgcctcag catgaattga gtctcatcca   2220

tatctgagtg atgtgatatt gagatgacac tttggagttt gagtttaaac attaggcttc   2280

atgctggaat taactgagac ttttgaggcc tttgggatga gatgaatata ttttacatgt   2340

gatgacatgg attttggggg ccagaggtgt aatgttttgg ctgagtgtat gccacctcag   2400

attcatatgt tgaaacctta cccccgtgcc ccccctctcc cccacaatgt gatggtattt   2460

ggaggccctg tctctggtgg tttttaggat tggaggacat catgaagatg gaggccttgt   2520

aattgggatt agtttcctga taggaatccc tagagagcta gctttgccct tcaccatgag   2580

agggtgcagt gagaagatag ctatctttga accgggaagc aggcccttac cagacatgga   2640

ctatgccagt gccttgatat tggacttccc agcctcccaa accatgagaa ataaatgttt   2700

gttgatt                                                             2707


<210>  9197
<211>  574
<212>  PRT
<213>  Homo sapiens

<400>  9197

Met Arg Arg His Asp Arg Leu Leu Phe Val Phe Leu Val Glu Thr Gly 
1               5                   10                  15


Phe Leu His Val Gly Gln Asp Ser Val Ala Ser Glu Asp Val Ala Val 
            20                  25                  30


Asn Phe Thr Leu Glu Glu Trp Ala Leu Leu Asp Pro Ser Gln Lys Lys 
        35                  40                  45


Leu Tyr Arg Asp Val Met Arg Glu Thr Phe Arg Asn Leu Ala Cys Val 
    50                  55                  60


Gly Lys Lys Trp Glu Asp Gln Ser Ile Glu Asp Trp Tyr Lys Asn Gln 
65                  70                  75                  80


Gly Arg Ile Leu Arg Asn His Met Glu Glu Gly Leu Ser Glu Ser Lys 
                85                  90                  95


Glu Tyr Asp Gln Cys Gly Glu Ala Phe Ser Gln Ile Leu Asn Leu Asn 
            100                 105                 110


Leu Asn Lys Lys Ile Pro Thr Ile Val Arg Pro Cys Glu Cys Ser Leu 
        115                 120                 125


Cys Gly Lys Val Phe Met His His Ser Ser Leu Ser Arg His Ile Arg 
    130                 135                 140


Ser His Leu Gly His Lys Pro Tyr Asp Tyr Gln Glu Tyr Gly Glu Lys 
145                 150                 155                 160


Pro Tyr Lys Cys Lys Gln Cys Gly Lys Ala Phe Ser Ser Cys Gln Ser 
                165                 170                 175


Phe Arg Arg His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Ala Cys 
            180                 185                 190


Pro Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser Val Arg Arg His 
        195                 200                 205


Met Ile Lys His Thr Gly Asp Gly Pro Tyr Lys Cys Gln Glu Cys Gly 
    210                 215                 220


Lys Ala Phe Asp Arg Pro Ser Leu Phe Gln Ile His Glu Arg Thr His 
225                 230                 235                 240


Thr Gly Glu Lys Pro Tyr Glu Cys Gln Glu Cys Ala Lys Ala Phe Ile 
                245                 250                 255


Ser Leu Pro Ser Phe Gln Arg His Met Ile Arg His Thr Gly Asp Gly 
            260                 265                 270


Pro Tyr Lys Cys Gln Glu Cys Gly Lys Ala Phe Asp Arg Pro Ser Leu 
        275                 280                 285


Phe Arg Ile His Glu Arg Thr His Thr Gly Glu Lys Pro His Glu Cys 
    290                 295                 300


Lys Gln Cys Gly Lys Ala Phe Ile Ser Phe Thr Asn Phe Gln Ser His 
305                 310                 315                 320


Met Ile Arg His Thr Gly Asp Gly Pro Tyr Lys Cys Lys Val Cys Gly 
                325                 330                 335


Arg Ala Phe Ile Phe Pro Ser Tyr Val Arg Lys His Glu Arg Thr His 
            340                 345                 350


Thr Gly Glu Lys Pro Tyr Glu Cys Asn Lys Cys Gly Lys Thr Phe Ser 
        355                 360                 365


Ser Ser Ser Asn Val Arg Thr His Glu Arg Thr His Thr Gly Glu Lys 
    370                 375                 380


Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Ile Ser Leu Pro Ser 
385                 390                 395                 400


Val Arg Arg His Met Ile Lys His Thr Gly Asp Gly Pro Tyr Lys Cys 
                405                 410                 415


Gln Val Cys Gly Arg Ala Phe Asp Cys Pro Ser Ser Phe Gln Ile His 
            420                 425                 430


Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys Gln Val Cys Gly 
        435                 440                 445


Lys Ala Phe Ile Ser Leu Lys Arg Ile Arg Lys His Met Ile Leu His 
    450                 455                 460


Thr Gly Asp Gly Pro Tyr Lys Cys Gln Val Cys Gly Lys Ala Phe Asp 
465                 470                 475                 480


Cys Pro Ser Ser Val Arg Thr His Glu Arg Thr His Thr Gly Glu Lys 
                485                 490                 495


Pro Tyr Glu Cys Lys Glu Cys Gly Lys Ala Phe Asn Tyr Ala Ser Ser 
            500                 505                 510


Ile Arg Ile His Glu Arg Thr His Thr Gly Glu Lys Pro Tyr Glu Cys 
        515                 520                 525


Lys Gln Cys Gly Lys Thr Phe Ser Tyr Ser Ser Ser Phe Gln Arg His 
    530                 535                 540


Glu Arg Ala His Asn Gly Asp Lys Pro Tyr Val Lys Asn Val Gly Lys 
545                 550                 555                 560


Leu Ser Phe Ile Thr Gln Pro Ser Asn Thr Cys Glu Asn Glu 
                565                 570


<210>  9198
<211>  533
<212>  DNA
<213>  Homo sapiens

<400>  9198
gattttctgc ctgttggatc tcttaattac tgctggaggg gtgctgcagt ctccaactat     60

acaaaggaat attttctttc aaccaacttg atctgtctac gtctgatggc ctggaatcct    120

tcaggaaagt gtggtcagct ggattttgtc agaacgtgga tttctacggg ccttctggcc    180

tctcatgttt gatgaaggga acagaagaaa atggtttcac ttcttcagtg tatatttatt    240

tattcatgga tacctttttc agtttttatc ctgtgtttct ttttttcttt ctttctttct    300

tttttttttt ttttttgaga cagagttttg ctcttgtcac ccaggctgga gtgcagtggc    360

acaatctcta ctcactgcaa cgtccgcctc ctggtctcaa gcgattctcc ttcctcagcc    420

tcccaagtag ctggtattac aggtgcccac caccacgccc agtgaatttt ttgtattttt    480

agtagagaca gggttttgcc atgttgggct ggctggtctc aaactcctga tct           533


<210>  9199
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  9199

Met Lys Gly Thr Glu Glu Asn Gly Phe Thr Ser Ser Val Tyr Ile Tyr 
1               5                   10                  15


Leu Phe Met Asp Thr Phe Phe Ser Phe Tyr Pro Val Phe Leu Phe Phe 
            20                  25                  30


Phe Leu Ser Phe Phe Phe Phe Phe Phe Leu Arg Gln Ser Phe Ala Leu 
        35                  40                  45


Val Thr Gln Ala Gly Val Gln Trp His Asn Leu Tyr Ser Leu Gln Arg 
    50                  55                  60


Pro Pro Pro Gly Leu Lys Arg Phe Ser Phe Leu Ser Leu Pro Ser Ser 
65                  70                  75                  80


Trp Tyr Tyr Arg Cys Pro Pro Pro Arg Pro Val Asn Phe Leu Tyr Phe 
                85                  90                  95


<210>  9200
<211>  1008
<212>  DNA
<213>  Homo sapiens

<400>  9200
agcggctgca gcctcctgat ttcatcgacc ccctagccaa caagaaaccc cggatatcgc     60

agcaagtgtg ggtgtgtgag tgtgcgtatg tggggacccc ccagggcatg gtggggtctg    120

aggcgtgtgt tcccatttag ggctgaatga agccatgact tggaaaggtg gtggggggtg    180

gatggcggct gtgactcagg gcccagggat cacatggggg tcactgctgc catcagcagt    240

caggcaggga gaacagaaat gcaaaaatac agatgtctat ttttctaaac tggggggtgg    300

aggggtgcct cctgacagct tccaaagagc tgactgtgga gggcccacag tgtatcccac    360

ccctgcccga gagtctctct cctttgggac ccccgggttc ccagagctcc gaggaaactg    420

atccttcatg tttcaatagc tgttgttgtt tttctctttg ggccgggccg ggccggggaa    480

gggccgagca ggctccagga ggcctccaga gtcagctgga ccttgctgtg tcgcccgcag    540

gcagccctgc agacaccggt gaggtgggat gatttcagga ggtcccagcc cgggactgcc    600

cgcccctctg ccctgggaac cagtccaagg ggctgtcagt tgaatttgcc tttttgttgt    660

tgttgttgtt tttgttgttt atttgttctc cttttaagga attatgaagc taagaaaagt    720

tttgtgtttt gggggttggt ggacaaagtt ctagctgatt aaatatggtc taacttattg    780

atactatttt tttttctttt aatgttgtac tgtggagaaa aactattttg agccatgggg    840

ttggtgttta caagaacttt ccacttttgc caaaatgtta caattgaaag gcatctatct    900

gcgtcttcag tttcctgata ttttcttaaa agatctagtg tcctttttgt acactaaaca    960

ggtgaatgct gacttttttc attctccaat aaatttcact gaactgaa                1008


<210>  9201
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  9201

Met Ser Ile Phe Leu Asn Trp Gly Val Glu Gly Cys Leu Leu Thr Ala 
1               5                   10                  15


Ser Lys Glu Leu Thr Val Glu Gly Pro Gln Cys Ile Pro Pro Leu Pro 
            20                  25                  30


Glu Ser Leu Ser Pro Leu Gly Pro Pro Gly Ser Gln Ser Ser Glu Glu 
        35                  40                  45


Thr Asp Pro Ser Cys Phe Asn Ser Cys Cys Cys Phe Ser Leu Trp Ala 
    50                  55                  60


Gly Pro Gly Arg Gly Arg Ala Glu Gln Ala Pro Gly Gly Leu Gln Ser 
65                  70                  75                  80


Gln Leu Asp Leu Ala Val Ser Pro Ala Gly Ser Pro Ala Asp Thr Gly 
                85                  90                  95


Glu Val Gly 



<210>  9202
<211>  487
<212>  DNA
<213>  Homo sapiens

<400>  9202
gtgagtgggg gcagcggggt gtcccagagg cccttccgtg accgagtgct gcacctcctg     60

gcactacggc cctaccgcaa ggctgagctg cctgggaacc agtccaaggg gctgtcagtt    120

gaatttgcct ttttgttgtt gttgttgttt ttgttgttta tttgttctcc ttttaaggaa    180

ttatgaagct aagaaaagtt ttgtgttttg ggggttggtg gacaaagttc tagctgatta    240

aatatggtct aacttattga tactattttt ttttctttta atgttgtact gtggagaaaa    300

actattttga gccatggggt tggtgtttac aagaactttc cacttttgcc aaaatgttac    360

aattgaaagg catctatctg cgtcttcagt ttcctgatat tttcttaaaa gatctagtgt    420

cctttttgta cactaaacag gtgaatgctg acttttttca ttctccaata aatttcactg    480

aactgaa                                                              487


<210>  9203
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9203

Met Leu Gln Leu Lys Gly Ile Tyr Leu Arg Leu Gln Phe Pro Asp Ile 
1               5                   10                  15


Phe Leu Lys Asp Leu Val Ser Phe Leu Tyr Thr Lys Gln Val Asn Ala 
            20                  25                  30


Asp Phe Phe His Ser Pro Ile Asn Phe Thr Glu 
        35                  40


<210>  9204
<211>  4081
<212>  DNA
<213>  Homo sapiens

<400>  9204
gcggggcgtg gccggcgtgg cggcgctgga gccgggaagg gggcgcgggg gagagatggt     60

cgcaagatgg cggcgctgaa ggaggatagg agctacgggc tgtcgtgcgg gcgggttagc    120

gacggcagca aggtgtcggt gttccacgtg aagctcaccg acagtgccct gagggccttc    180

gagagctacc gcgccagaca ggattctgtt tcactgaggc catctatccg atttcaagga    240

agccaagggc ctgagagctc tgcacagctg gatgtgggga tatggacatg atgatccatg    300

ggcttccagc acatctccat cccccagcct gactgccccg cagaggcgcg gacgttctcc    360

ttctacctct ccaacatcgg ccgcgacaac ccccagggca gcttcgactg catccagcag    420

tatgtctcca gtcatgggga agttcacctg gactgcctgg gcagcataca ggacaagatc    480

acggtgtgtg ccaccgacga ctcctaccag aaggcgcggc agagcatggc ccaggcggag    540

gaggagacgc ggagccgaag tgccattgtc atcaaggctg gaggccgcta cctgggcaag    600

aaggttcagt ttcggaaacc agccccaggt gcaacagacg cggtgccctc ccggaagcgg    660

gcaaccccca tcaacttggc gagtgccatc aggaagagtg gtgccagtgc cgtgagtggg    720

ggcagcgggg tgtcccagag gcccttccgt gaccgagtgc tgcacctcct ggcactacgg    780

ccctaccgca aggctgagct gctgctgcga ctgcagaagg acggcctgac gcaggcggac    840

aaggacgcgc tggatggcct cctccagcag gtggccaaca tgagtgctaa ggacggcacg    900

tgtacactgc aggactgcat gtacaaggat gtgcagaagg actggcctgg ctactcggag    960

ggggaccagc agctgctgaa gcgggtgctc gtccggaagc tgtgccagcc acagagcact   1020

ggcagcctcc ttggagaccc tgctgcctcc agccccccag gcgagcgtgg gcgctcggcc   1080

tcgcccccac agaagcggct gcagcctcct gatttcatcg accccctagc caacaagaaa   1140

ccccggatat cgcacttcac tcagagagct cagcctgccg tcaacgggaa gctgggcgtg   1200

cccaatggcc gtgaggcctt gctgcccacc ccgggcccac cagccagcac ggacaccctc   1260

agctccagca ctcacctgcc cccgcggctg gagcccccga gggcccacga ccccctggcc   1320

gatgtcagca atgacctggg ccacagcggc cgagactgtg agcacggaga ggcggctgcc   1380

ccagccccca ctgtgcgcct cggcctgccc ctgctgacgg actgtgccca gcccagcagg   1440

ccacacggca gcccctcgcg cagcaagccc aagaagaagt ccaagaagca caaagacaag   1500

gagagggcgg ctgaggacaa gccccgggcc cagcttccag actgtgcacc tgccacccat   1560

gccacccccg gagccccagc agacacccca ggtttaaacg gaacctgcag cgtttccagt   1620

gttcccacgt ccacgtcgga gacgcctgac tacttgctga agtacgcagc catctcctct   1680

tcggagcagc gccagagcta caagaacgac ttcaatgccg agtacagcga gtaccgcgac   1740

ctgcacgccc gcattgagcg catcacgcgg cggttcaccc agctcgacgc ccagctccgg   1800

cagctctccc agggctccga ggagtatgag actactcgag ggcagatttt gcaggaatat   1860

cgaaaaatca aaaagaccaa caccaactac agccaggaga agcaccgctg cgagtacctg   1920

cacagcaagc tggcccacat caagaggctc atcgccgagt acgaccagcg gcagctgcag   1980

gcttggccct agccgccctc cccgatggcg gggatctggg agggtcgggg gagcaaaagg   2040

cggtgagaga ggatttattt aaaaaaataa acccgaggaa gatgctcatc tgagccagca   2100

ccgccggctt tcagggcagc ccctgcagac gtctggccct ggcgggtggc tgcaagccca   2160

cctcggccct ccctgcgctt cctgagcagt ccctgcttat gatgggctcc ccaggaagcc   2220

cactgcctcc tccctggctg cagcctccgg ggttcagcct cctgtctcgc cagaagactc   2280

ctaggccctt ggggtggcgc gcctgccttt tctagtttta tacaaagaca gccactttta   2340

gctactgcta atgagacttg agtctatttt tgtacaaaag agaagcaaaa tcttttttct   2400

aaacctgtgc ctccctctcc tcggacaccc agggtctagc cgctgccctg ggtcctgcct   2460

gcagtattac agaggtcgtc gaaaggtgca gctgcgttct gagggcgtgg ggaatgggca   2520

ggtggcctct gctggtctct ggctctacgt ttaggcaccc ctttccccag cctctcctcc   2580

ttgggcaggg tctctgctcc agcaagcaaa cagggtggcc caggtggcta ttttgagaac   2640

tccagctggt gcccccagac agctgctcag agccaagggg gcagagggct ttcagcgccc   2700

ccaggcctgc cctgctattt caggccctca gctgtcgggg gccactgtgt ttctgtgctc   2760

caagttgaga ctcggccgca gcggcgtcag acttttcttt gcgatgtcct cggtttccca   2820

tttgttgctg ctgctgctca ttccacactg ttgagacctt gtggtctcga tgctgctggc   2880

ctccctccgt ccctctgtcc acttgtgggt cctggggtcg tcttagcaga gccaccgcca   2940

aggtttgcac tcagggaggg gctgatggag ggctgggcgc catggggtca gggaggcccc   3000

agggacccat gggcagagct ggggagccag gaggatgggt ctgcctgctc tgggggtgca   3060

ggctctgcag acaccccaat tgctgctctg ttgctgtgcc tagtctagtg tcccccaaag   3120

catcgggggg ccacgcaagt gtgggtgtgt gagtgtgcgt atgtggggac cccccagggc   3180

atggtggggt ctgaggcgtg tgttcccatt tagggctgaa tgaagccatg acttggaaag   3240

gtggtggggg gtggatggcg gctgtgactc agggcccagg gatcacatgg gggtcactgc   3300

tgccatcagc agtcaggcag ggagaacaga aatgcaaaaa tacagatgtc tatttttcta   3360

aactgggggg tggaggggtg cctcctgaca gcttccaaag agctgactgt ggagggccca   3420

cagtgtatcc cacccctgcc cgagagtctc tctcctttgg gacccccggg ttcccagagc   3480

tccgaggaaa ctgatccttc atgtttcaat agctgttgtt gtttttctct ttgggccggg   3540

ccgggccggg gaagggccga gcaggctcca ggaggcctcc agagtcagct ggaccttgct   3600

gtgtcgcccg caggcagccc tgcagacacc ggtgaggtgg gatgatttca ggaggtccca   3660

gcccgggact gcccgcccct ctgccctggg aaccagtcca aggggctgtc agttgaattt   3720

gcctttttgt tgttgttgtt gtttttgttg tttatttgtt ctccttttaa ggaattatga   3780

agctaagaaa agttttgtgt tttgggggtt ggtggacaaa gttctagctg attaaatatg   3840

gtctaactta ttgatactat ttttttttct tttaatgttg tactgtggag aaaaactatt   3900

ttgagccatg gggttggtgt ttacaagaac tttccacttt tgccaaaatg ttacaattga   3960

aaggcatcta tctgcgtctt cagtttcctg atattttctt aaaagatcta gtgtcctttt   4020

tgtacactaa acaggtgaat gctgactttt ttcattctcc aataaatttc actgaactga   4080

a                                                                   4081


<210>  9205
<211>  564
<212>  PRT
<213>  Homo sapiens

<400>  9205

Met Gly Phe Gln His Ile Ser Ile Pro Gln Pro Asp Cys Pro Ala Glu 
1               5                   10                  15


Ala Arg Thr Phe Ser Phe Tyr Leu Ser Asn Ile Gly Arg Asp Asn Pro 
            20                  25                  30


Gln Gly Ser Phe Asp Cys Ile Gln Gln Tyr Val Ser Ser His Gly Glu 
        35                  40                  45


Val His Leu Asp Cys Leu Gly Ser Ile Gln Asp Lys Ile Thr Val Cys 
    50                  55                  60


Ala Thr Asp Asp Ser Tyr Gln Lys Ala Arg Gln Ser Met Ala Gln Ala 
65                  70                  75                  80


Glu Glu Glu Thr Arg Ser Arg Ser Ala Ile Val Ile Lys Ala Gly Gly 
                85                  90                  95


Arg Tyr Leu Gly Lys Lys Val Gln Phe Arg Lys Pro Ala Pro Gly Ala 
            100                 105                 110


Thr Asp Ala Val Pro Ser Arg Lys Arg Ala Thr Pro Ile Asn Leu Ala 
        115                 120                 125


Ser Ala Ile Arg Lys Ser Gly Ala Ser Ala Val Ser Gly Gly Ser Gly 
    130                 135                 140


Val Ser Gln Arg Pro Phe Arg Asp Arg Val Leu His Leu Leu Ala Leu 
145                 150                 155                 160


Arg Pro Tyr Arg Lys Ala Glu Leu Leu Leu Arg Leu Gln Lys Asp Gly 
                165                 170                 175


Leu Thr Gln Ala Asp Lys Asp Ala Leu Asp Gly Leu Leu Gln Gln Val 
            180                 185                 190


Ala Asn Met Ser Ala Lys Asp Gly Thr Cys Thr Leu Gln Asp Cys Met 
        195                 200                 205


Tyr Lys Asp Val Gln Lys Asp Trp Pro Gly Tyr Ser Glu Gly Asp Gln 
    210                 215                 220


Gln Leu Leu Lys Arg Val Leu Val Arg Lys Leu Cys Gln Pro Gln Ser 
225                 230                 235                 240


Thr Gly Ser Leu Leu Gly Asp Pro Ala Ala Ser Ser Pro Pro Gly Glu 
                245                 250                 255


Arg Gly Arg Ser Ala Ser Pro Pro Gln Lys Arg Leu Gln Pro Pro Asp 
            260                 265                 270


Phe Ile Asp Pro Leu Ala Asn Lys Lys Pro Arg Ile Ser His Phe Thr 
        275                 280                 285


Gln Arg Ala Gln Pro Ala Val Asn Gly Lys Leu Gly Val Pro Asn Gly 
    290                 295                 300


Arg Glu Ala Leu Leu Pro Thr Pro Gly Pro Pro Ala Ser Thr Asp Thr 
305                 310                 315                 320


Leu Ser Ser Ser Thr His Leu Pro Pro Arg Leu Glu Pro Pro Arg Ala 
                325                 330                 335


His Asp Pro Leu Ala Asp Val Ser Asn Asp Leu Gly His Ser Gly Arg 
            340                 345                 350


Asp Cys Glu His Gly Glu Ala Ala Ala Pro Ala Pro Thr Val Arg Leu 
        355                 360                 365


Gly Leu Pro Leu Leu Thr Asp Cys Ala Gln Pro Ser Arg Pro His Gly 
    370                 375                 380


Ser Pro Ser Arg Ser Lys Pro Lys Lys Lys Ser Lys Lys His Lys Asp 
385                 390                 395                 400


Lys Glu Arg Ala Ala Glu Asp Lys Pro Arg Ala Gln Leu Pro Asp Cys 
                405                 410                 415


Ala Pro Ala Thr His Ala Thr Pro Gly Ala Pro Ala Asp Thr Pro Gly 
            420                 425                 430


Leu Asn Gly Thr Cys Ser Val Ser Ser Val Pro Thr Ser Thr Ser Glu 
        435                 440                 445


Thr Pro Asp Tyr Leu Leu Lys Tyr Ala Ala Ile Ser Ser Ser Glu Gln 
    450                 455                 460


Arg Gln Ser Tyr Lys Asn Asp Phe Asn Ala Glu Tyr Ser Glu Tyr Arg 
465                 470                 475                 480


Asp Leu His Ala Arg Ile Glu Arg Ile Thr Arg Arg Phe Thr Gln Leu 
                485                 490                 495


Asp Ala Gln Leu Arg Gln Leu Ser Gln Gly Ser Glu Glu Tyr Glu Thr 
            500                 505                 510


Thr Arg Gly Gln Ile Leu Gln Glu Tyr Arg Lys Ile Lys Lys Thr Asn 
        515                 520                 525


Thr Asn Tyr Ser Gln Glu Lys His Arg Cys Glu Tyr Leu His Ser Lys 
    530                 535                 540


Leu Ala His Ile Lys Arg Leu Ile Ala Glu Tyr Asp Gln Arg Gln Leu 
545                 550                 555                 560


Gln Ala Trp Pro 



<210>  9206
<211>  4027
<212>  DNA
<213>  Homo sapiens

<400>  9206
ggcggggcgg ggcgtggccg gcgtggcggc gctggagccg ggaagggggc gcgggggaga     60

gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg    120

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    180

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    240

caaggaagcc aagggcacat ctccatcccc cagcctgact gccccgcaga ggcgcggacg    300

ttctccttct acctctccaa catcggccgc gacaaccccc agggcagctt cgactgcatc    360

cagcagtatg tctccagtca tggggaagtt cacctggact gcctgggcag catacaggac    420

aagatcacgg tgtgtgccac cgacgactcc taccagaagg cgcggcagag catggcccag    480

gcggaggagg agacgcggag ccgaagtgcc attgtcatca aggctggagg ccgctacctg    540

ggcaagaagg ttcagtttcg gaaaccagcc ccaggtgcaa cagacgcggt gccctcccgg    600

aagcgggcaa cccccatcaa cttggcgagt gccatcagga agagtggtgc cagtgccgtg    660

agtgggggca gcggggtgtc ccagaggccc ttccgtgacc gagtgctgca cctcctggca    720

ctacggccct accgcaaggc tgagctgctg ctgcgactgc agaaggacgg cctgacgcag    780

gcggacaagg acgcgctgga tggcctcctc cagcaggtgg ccaacatgag tgctaaggac    840

ggcacgtgta cactgcagga ctgcatgtac aaggatgtgc agaaggactg gcctggctac    900

tcggaggggg accagcagct gctgaagcgg gtgctcgtcc ggaagctgtg ccagccacag    960

agcactggca gcctccttgg agaccctgct gcctccagcc ccccaggcga gcgtgggcgc   1020

tcggcctcgc ccccacagaa gcggctgcag cctcctgatt tcatcgaccc cctagccaac   1080

aagaaacccc ggatatcgca cttcactcag agagctcagc ctgccgtcaa cgggaagctg   1140

ggcgtgccca atggccgtga ggccttgctg cccaccccgg gcccaccagc cagcacggac   1200

accctcagct ccagcactca cctgcccccg cggctggagc ccccgagggc ccacgacccc   1260

ctggccgatg tcagcaatga cctgggccac agcggccgag actgtgagca cggagaggcg   1320

gctgccccag cccccactgt gcgcctcggc ctgcccctgc tgacggactg tgcccagccc   1380

agcaggccac acggcagccc ctcgcgcagc aagcccaaga agaagtccaa gaagcacaaa   1440

gacaaggaga gggcggctga ggacaagccc cgggcccagc ttccagactg tgcacctgcc   1500

acccatgcca cccccggagc cccagcagac accccaggtt taaacggaac ctgcagcgtt   1560

tccagtgttc ccacgtccac gtcggagacg cctgactact tgctgaagta cgcagccatc   1620

tcctcttcgg agcagcgcca gagctacaag aacgacttca atgccgagta cagcgagtac   1680

cgcgacctgc acgcccgcat tgagcgcatc acgcggcggt tcacccagct cgacgcccag   1740

ctccggcagc tctcccaggg ctccgaggag tatgagacta ctcgagggca gattttgcag   1800

gaatatcgaa aaatcaaaaa gaccaacacc aactacagcc aggagaagca ccgctgcgag   1860

tacctgcaca gcaagctggc ccacatcaag aggctcatcg ccgagtacga ccagcggcag   1920

ctgcaggctt ggccctagcc gccctccccg atggcgggga tctgggaggg tcgggggagc   1980

aaaaggcggt gagagaggat ttatttaaaa aaataaaccc gaggaagatg ctcatctgag   2040

ccagcaccgc cggctttcag ggcagcccct gcagacgtct ggccctggcg ggtggctgca   2100

agcccacctc ggccctccct gcgcttcctg agcagtccct gcttatgatg ggctccccag   2160

gaagcccact gcctcctccc tggctgcagc ctccggggtt cagcctcctg tctcgccaga   2220

agactcctag gcccttgggg tggcgcgcct gccttttcta gttttataca aagacagcca   2280

cttttagcta ctgctaatga gacttgagtc tatttttgta caaaagagaa gcaaaatctt   2340

ttttctaaac ctgtgcctcc ctctcctcgg acacccaggg tctagccgct gccctgggtc   2400

ctgcctgcag tattacagag gtcgtcgaaa ggtgcagctg cgttctgagg gcgtggggaa   2460

tgggcaggtg gcctctgctg gtctctggct ctacgtttag gcaccccttt ccccagcctc   2520

tcctccttgg gcagggtctc tgctccagca agcaaacagg gtggcccagg tggctatttt   2580

gagaactcca gctggtgccc ccagacagct gctcagagcc aagggggcag agggctttca   2640

gcgcccccag gcctgccctg ctatttcagg ccctcagctg tcgggggcca ctgtgtttct   2700

gtgctccaag ttgagactcg gccgcagcgg cgtcagactt ttctttgcga tgtcctcggt   2760

ttcccatttg ttgctgctgc tgctcattcc acactgttga gaccttgtgg tctcgatgct   2820

gctggcctcc ctccgtccct ctgtccactt gtgggtcctg gggtcgtctt agcagagcca   2880

ccgccaaggt ttgcactcag ggaggggctg atggagggct gggcgccatg gggtcaggga   2940

ggccccaggg acccatgggc agagctgggg agccaggagg atgggtctgc ctgctctggg   3000

ggtgcaggct ctgcagacac cccaattgct gctctgttgc tgtgcctagt ctagtgtccc   3060

ccaaagcatc ggggggccac gcaagtgtgg gtgtgtgagt gtgcgtatgt ggggaccccc   3120

cagggcatgg tggggtctga ggcgtgtgtt cccatttagg gctgaatgaa gccatgactt   3180

ggaaaggtgg tggggggtgg atggcggctg tgactcaggg cccagggatc acatgggggt   3240

cactgctgcc atcagcagtc aggcagggag aacagaaatg caaaaataca gatgtctatt   3300

tttctaaact ggggggtgga ggggtgcctc ctgacagctt ccaaagagct gactgtggag   3360

ggcccacagt gtatcccacc cctgcccgag agtctctctc ctttgggacc cccgggttcc   3420

cagagctccg aggaaactga tccttcatgt ttcaatagct gttgttgttt ttctctttgg   3480

gccgggccgg gccggggaag ggccgagcag gctccaggag gcctccagag tcagctggac   3540

cttgctgtgt cgcccgcagg cagccctgca gacaccggtg aggtgggatg atttcaggag   3600

gtcccagccc gggactgccc gcccctctgc cctgggaacc agtccaaggg gctgtcagtt   3660

gaatttgcct ttttgttgtt gttgttgttt ttgttgttta tttgttctcc ttttaaggaa   3720

ttatgaagct aagaaaagtt ttgtgttttg ggggttggtg gacaaagttc tagctgatta   3780

aatatggtct aacttattga tactattttt ttttctttta atgttgtact gtggagaaaa   3840

actattttga gccatggggt tggtgtttac aagaactttc cacttttgcc aaaatgttac   3900

aattgaaagg catctatctg cgtcttcagt ttcctgatat tttcttaaaa gatctagtgt   3960

cctttttgta cactaaacag gtgaatgctg acttttttca ttctccaata aatttcactg   4020

aactgaa                                                             4027


<210>  9207
<211>  621
<212>  PRT
<213>  Homo sapiens

<400>  9207

Met Ala Ala Leu Lys Glu Asp Arg Ser Tyr Gly Leu Ser Cys Gly Arg 
1               5                   10                  15


Val Ser Asp Gly Ser Lys Val Ser Val Phe His Val Lys Leu Thr Asp 
            20                  25                  30


Ser Ala Leu Arg Ala Phe Glu Ser Tyr Arg Ala Arg Gln Asp Ser Val 
        35                  40                  45


Ser Leu Arg Pro Ser Ile Arg Phe Gln Gly Ser Gln Gly His Ile Ser 
    50                  55                  60


Ile Pro Gln Pro Asp Cys Pro Ala Glu Ala Arg Thr Phe Ser Phe Tyr 
65                  70                  75                  80


Leu Ser Asn Ile Gly Arg Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile 
                85                  90                  95


Gln Gln Tyr Val Ser Ser His Gly Glu Val His Leu Asp Cys Leu Gly 
            100                 105                 110


Ser Ile Gln Asp Lys Ile Thr Val Cys Ala Thr Asp Asp Ser Tyr Gln 
        115                 120                 125


Lys Ala Arg Gln Ser Met Ala Gln Ala Glu Glu Glu Thr Arg Ser Arg 
    130                 135                 140


Ser Ala Ile Val Ile Lys Ala Gly Gly Arg Tyr Leu Gly Lys Lys Val 
145                 150                 155                 160


Gln Phe Arg Lys Pro Ala Pro Gly Ala Thr Asp Ala Val Pro Ser Arg 
                165                 170                 175


Lys Arg Ala Thr Pro Ile Asn Leu Ala Ser Ala Ile Arg Lys Ser Gly 
            180                 185                 190


Ala Ser Ala Val Ser Gly Gly Ser Gly Val Ser Gln Arg Pro Phe Arg 
        195                 200                 205


Asp Arg Val Leu His Leu Leu Ala Leu Arg Pro Tyr Arg Lys Ala Glu 
    210                 215                 220


Leu Leu Leu Arg Leu Gln Lys Asp Gly Leu Thr Gln Ala Asp Lys Asp 
225                 230                 235                 240


Ala Leu Asp Gly Leu Leu Gln Gln Val Ala Asn Met Ser Ala Lys Asp 
                245                 250                 255


Gly Thr Cys Thr Leu Gln Asp Cys Met Tyr Lys Asp Val Gln Lys Asp 
            260                 265                 270


Trp Pro Gly Tyr Ser Glu Gly Asp Gln Gln Leu Leu Lys Arg Val Leu 
        275                 280                 285


Val Arg Lys Leu Cys Gln Pro Gln Ser Thr Gly Ser Leu Leu Gly Asp 
    290                 295                 300


Pro Ala Ala Ser Ser Pro Pro Gly Glu Arg Gly Arg Ser Ala Ser Pro 
305                 310                 315                 320


Pro Gln Lys Arg Leu Gln Pro Pro Asp Phe Ile Asp Pro Leu Ala Asn 
                325                 330                 335


Lys Lys Pro Arg Ile Ser His Phe Thr Gln Arg Ala Gln Pro Ala Val 
            340                 345                 350


Asn Gly Lys Leu Gly Val Pro Asn Gly Arg Glu Ala Leu Leu Pro Thr 
        355                 360                 365


Pro Gly Pro Pro Ala Ser Thr Asp Thr Leu Ser Ser Ser Thr His Leu 
    370                 375                 380


Pro Pro Arg Leu Glu Pro Pro Arg Ala His Asp Pro Leu Ala Asp Val 
385                 390                 395                 400


Ser Asn Asp Leu Gly His Ser Gly Arg Asp Cys Glu His Gly Glu Ala 
                405                 410                 415


Ala Ala Pro Ala Pro Thr Val Arg Leu Gly Leu Pro Leu Leu Thr Asp 
            420                 425                 430


Cys Ala Gln Pro Ser Arg Pro His Gly Ser Pro Ser Arg Ser Lys Pro 
        435                 440                 445


Lys Lys Lys Ser Lys Lys His Lys Asp Lys Glu Arg Ala Ala Glu Asp 
    450                 455                 460


Lys Pro Arg Ala Gln Leu Pro Asp Cys Ala Pro Ala Thr His Ala Thr 
465                 470                 475                 480


Pro Gly Ala Pro Ala Asp Thr Pro Gly Leu Asn Gly Thr Cys Ser Val 
                485                 490                 495


Ser Ser Val Pro Thr Ser Thr Ser Glu Thr Pro Asp Tyr Leu Leu Lys 
            500                 505                 510


Tyr Ala Ala Ile Ser Ser Ser Glu Gln Arg Gln Ser Tyr Lys Asn Asp 
        515                 520                 525


Phe Asn Ala Glu Tyr Ser Glu Tyr Arg Asp Leu His Ala Arg Ile Glu 
    530                 535                 540


Arg Ile Thr Arg Arg Phe Thr Gln Leu Asp Ala Gln Leu Arg Gln Leu 
545                 550                 555                 560


Ser Gln Gly Ser Glu Glu Tyr Glu Thr Thr Arg Gly Gln Ile Leu Gln 
                565                 570                 575


Glu Tyr Arg Lys Ile Lys Lys Thr Asn Thr Asn Tyr Ser Gln Glu Lys 
            580                 585                 590


His Arg Cys Glu Tyr Leu His Ser Lys Leu Ala His Ile Lys Arg Leu 
        595                 600                 605


Ile Ala Glu Tyr Asp Gln Arg Gln Leu Gln Ala Trp Pro 
    610                 615                 620


<210>  9208
<211>  778
<212>  DNA
<213>  Homo sapiens

<400>  9208
agcggctgca gcctcctgat ttcatcgacc ccctagccaa caagaaaccc cggatatcgc     60

agcaagtgtg ggtgtgtgag tgtgcgtatg tggggacccc ccagggcatg gtggggtctg    120

aggcgtgtgt tcccatttag ggctgaatga agccatgact tggaaaggtg gtggggggtg    180

gatggcggct gtgactcagg gcccagggat cacatggggg tcactgctgc catcagcagt    240

caggcaggga gaacagaaat gcaaaaatac agatgtctat ttttctaaac tggggggtgg    300

aggggtgcct cctgacagct tccaaagagc tgactgtgga gggcccacag tgtatcccac    360

ccctgcccga gagtctctct cctttgggac ccccgggttc ccagagctcc gaggaaactg    420

atccttcatg tttcaatagc tgttgttgtt tttctctttg ggccgggccg ggccggggaa    480

gggccgagca ggctccagga ggcctccaga gtcagctgga ccttgctgtg tcgcccgcag    540

gcagccctgc agacaccggt gaggtgggat gatttcagga ggtcccagcc cgggactgcc    600

cgcccctctg ccctgggaac cagtccaagg ggctgtcagt tgaatttgcc tttttgttgt    660

tgttgttgtt tttgttgttt atttgttctc cttttaagga attatgaagc taagaaaagt    720

tttgtgtttt gggggttggt ggacaaagtt ctagctgatt aaatatggtc taacttat      778


<210>  9209
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  9209

Met Ser Ile Phe Leu Asn Trp Gly Val Glu Gly Cys Leu Leu Thr Ala 
1               5                   10                  15


Ser Lys Glu Leu Thr Val Glu Gly Pro Gln Cys Ile Pro Pro Leu Pro 
            20                  25                  30


Glu Ser Leu Ser Pro Leu Gly Pro Pro Gly Ser Gln Ser Ser Glu Glu 
        35                  40                  45


Thr Asp Pro Ser Cys Phe Asn Ser Cys Cys Cys Phe Ser Leu Trp Ala 
    50                  55                  60


Gly Pro Gly Arg Gly Arg Ala Glu Gln Ala Pro Gly Gly Leu Gln Ser 
65                  70                  75                  80


Gln Leu Asp Leu Ala Val Ser Pro Ala Gly Ser Pro Ala Asp Thr Gly 
                85                  90                  95


Glu Val Gly 



<210>  9210
<211>  3797
<212>  DNA
<213>  Homo sapiens

<400>  9210
ggcggggcgg ggcgtggccg gcgtggcggc gctggagccg ggaagggggc gcgggggaga     60

gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg    120

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    180

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    240

caaggaagcc aagggcacat ctccatcccc cagcctgact gccccgcaga ggcgcggacg    300

ttctccttct acctctccaa catcggccgc gacaaccccc agggcagctt cgactgcatc    360

cagcagtatg tctccagtca tggggaagtt cacctggact gcctgggcag catacaggac    420

aagatcacgg tgtgtgccac cgacgactcc taccagaagg cgcggcagag catggcccag    480

gcggaggagg agacgcggag ccgaagtgcc attgtcatca aggctggagg ccgctacctg    540

ggcaagaagg ttcagtttcg gaaaccagcc ccaggtgcaa cagacgcggt gccctcccgg    600

aagcgggcaa cccccatcaa cttggcgagt gccatcagga agagtggtgc cagtgccgtg    660

agtgggggca gcggggtgtc ccagaggccc ttccgtgacc gagtgctgca cctcctggca    720

ctacggccct accgcaaggc tgagctgctg ctgcgactgc agaaggacgg cctgacgcag    780

gcggacaagg acgcgctgga tggcctcctc cagcaggtgg ccaacatgag tgctaaggac    840

ggcacgtgta cactgcagga ctgcatgtac aaggatgtgc agaaggactg gcctggctac    900

tcggaggggg accagcagct gctgaagcgg gtgctcgtcc ggaagctgtg ccagccacag    960

agcactggca gcctccttgg agaccctgct gcctccagcc ccccaggcga gcgtgggcgc   1020

tcggcctcgc ccccacagaa gcggctgcag cctcctgatt tcatcgaccc cctagccaac   1080

aagaaacccc ggatatcgca cttcactcag agagctcagc ctgccgtcaa cgggaagctg   1140

ggcgtgccca atggccgtga ggccttgctg cccaccccgg gcccaccagc cagcacggac   1200

accctcagct ccagcactca cctgcccccg cggctggagc ccccgagggc ccacgacccc   1260

ctggccgatg tcagcaatga cctgggccac agcggccgag actgtgagca cggagaggcg   1320

gctgccccag cccccactgt gcgcctcggc ctgcccctgc tgacggactg tgcccagccc   1380

agcaggccac acggcagccc ctcgcgcagc aagcccaaga agaagtccaa gaagcacaaa   1440

gacaaggaga gggcggctga ggacaagccc cgggcccagc ttccagactg tgcacctgcc   1500

acccatgcca cccccggagc cccagcagac accccaggtt taaacggaac ctgcagcgtt   1560

tccagtgttc ccacgtccac gtcggagacg cctgactact tgctgaagta cgcagccatc   1620

tcctcttcgg agcagcgcca gagctacaag aacgacttca atgccgagta cagcgagtac   1680

cgcgacctgc acgcccgcat tgagcgcatc acgcggcggt tcacccagct cgacgcccag   1740

ctccggcagc tctcccaggg ctccgaggag tatgagacta ctcgagggca gattttgcag   1800

gaatatcgaa aaatcaaaaa gaccaacacc aactacagcc aggagaagca ccgctgcgag   1860

tacctgcaca gcaagctggc ccacatcaag aggctcatcg ccgagtacga ccagcggcag   1920

ctgcaggctt ggccctagcc gccctccccg atggcgggga tctgggaggg tcgggggagc   1980

aaaaggcggt gagagaggat ttatttaaaa aaataaaccc gaggaagatg ctcatctgag   2040

ccagcaccgc cggctttcag ggcagcccct gcagacgtct ggccctggcg ggtggctgca   2100

agcccacctc ggccctccct gcgcttcctg agcagtccct gcttatgatg ggctccccag   2160

gaagcccact gcctcctccc tggctgcagc ctccggggtt cagcctcctg tctcgccaga   2220

agactcctag gcccttgggg tggcgcgcct gccttttcta gttttataca aagacagcca   2280

cttttagcta ctgctaatga gacttgagtc tatttttgta caaaagagaa gcaaaatctt   2340

ttttctaaac ctgtgcctcc ctctcctcgg acacccaggg tctagccgct gccctgggtc   2400

ctgcctgcag tattacagag gtcgtcgaaa ggtgcagctg cgttctgagg gcgtggggaa   2460

tgggcaggtg gcctctgctg gtctctggct ctacgtttag gcaccccttt ccccagcctc   2520

tcctccttgg gcagggtctc tgctccagca agcaaacagg gtggcccagg tggctatttt   2580

gagaactcca gctggtgccc ccagacagct gctcagagcc aagggggcag agggctttca   2640

gcgcccccag gcctgccctg ctatttcagg ccctcagctg tcgggggcca ctgtgtttct   2700

gtgctccaag ttgagactcg gccgcagcgg cgtcagactt ttctttgcga tgtcctcggt   2760

ttcccatttg ttgctgctgc tgctcattcc acactgttga gaccttgtgg tctcgatgct   2820

gctggcctcc ctccgtccct ctgtccactt gtgggtcctg gggtcgtctt agcagagcca   2880

ccgccaaggt ttgcactcag ggaggggctg atggagggct gggcgccatg gggtcaggga   2940

ggccccaggg acccatgggc agagctgggg agccaggagg atgggtctgc ctgctctggg   3000

ggtgcaggct ctgcagacac cccaattgct gctctgttgc tgtgcctagt ctagtgtccc   3060

ccaaagcatc ggggggccac gcaagtgtgg gtgtgtgagt gtgcgtatgt ggggaccccc   3120

cagggcatgg tggggtctga ggcgtgtgtt cccatttagg gctgaatgaa gccatgactt   3180

ggaaaggtgg tggggggtgg atggcggctg tgactcaggg cccagggatc acatgggggt   3240

cactgctgcc atcagcagtc aggcagggag aacagaaatg caaaaataca gatgtctatt   3300

tttctaaact ggggggtgga ggggtgcctc ctgacagctt ccaaagagct gactgtggag   3360

ggcccacagt gtatcccacc cctgcccgag agtctctctc ctttgggacc cccgggttcc   3420

cagagctccg aggaaactga tccttcatgt ttcaatagct gttgttgttt ttctctttgg   3480

gccgggccgg gccggggaag ggccgagcag gctccaggag gcctccagag tcagctggac   3540

cttgctgtgt cgcccgcagg cagccctgca gacaccggtg aggtgggatg atttcaggag   3600

gtcccagccc gggactgccc gcccctctgc cctgggaacc agtccaaggg gctgtcagtt   3660

gaatttgcct ttttgttgtt gttgttgttt ttgttgttta tttgttctcc ttttaaggaa   3720

ttatgaagct aagaaaagtt ttgtgttttg ggggttggtg gacaaagttc tagctgatta   3780

aatatggtct aacttat                                                  3797


<210>  9211
<211>  621
<212>  PRT
<213>  Homo sapiens

<400>  9211

Met Ala Ala Leu Lys Glu Asp Arg Ser Tyr Gly Leu Ser Cys Gly Arg 
1               5                   10                  15


Val Ser Asp Gly Ser Lys Val Ser Val Phe His Val Lys Leu Thr Asp 
            20                  25                  30


Ser Ala Leu Arg Ala Phe Glu Ser Tyr Arg Ala Arg Gln Asp Ser Val 
        35                  40                  45


Ser Leu Arg Pro Ser Ile Arg Phe Gln Gly Ser Gln Gly His Ile Ser 
    50                  55                  60


Ile Pro Gln Pro Asp Cys Pro Ala Glu Ala Arg Thr Phe Ser Phe Tyr 
65                  70                  75                  80


Leu Ser Asn Ile Gly Arg Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile 
                85                  90                  95


Gln Gln Tyr Val Ser Ser His Gly Glu Val His Leu Asp Cys Leu Gly 
            100                 105                 110


Ser Ile Gln Asp Lys Ile Thr Val Cys Ala Thr Asp Asp Ser Tyr Gln 
        115                 120                 125


Lys Ala Arg Gln Ser Met Ala Gln Ala Glu Glu Glu Thr Arg Ser Arg 
    130                 135                 140


Ser Ala Ile Val Ile Lys Ala Gly Gly Arg Tyr Leu Gly Lys Lys Val 
145                 150                 155                 160


Gln Phe Arg Lys Pro Ala Pro Gly Ala Thr Asp Ala Val Pro Ser Arg 
                165                 170                 175


Lys Arg Ala Thr Pro Ile Asn Leu Ala Ser Ala Ile Arg Lys Ser Gly 
            180                 185                 190


Ala Ser Ala Val Ser Gly Gly Ser Gly Val Ser Gln Arg Pro Phe Arg 
        195                 200                 205


Asp Arg Val Leu His Leu Leu Ala Leu Arg Pro Tyr Arg Lys Ala Glu 
    210                 215                 220


Leu Leu Leu Arg Leu Gln Lys Asp Gly Leu Thr Gln Ala Asp Lys Asp 
225                 230                 235                 240


Ala Leu Asp Gly Leu Leu Gln Gln Val Ala Asn Met Ser Ala Lys Asp 
                245                 250                 255


Gly Thr Cys Thr Leu Gln Asp Cys Met Tyr Lys Asp Val Gln Lys Asp 
            260                 265                 270


Trp Pro Gly Tyr Ser Glu Gly Asp Gln Gln Leu Leu Lys Arg Val Leu 
        275                 280                 285


Val Arg Lys Leu Cys Gln Pro Gln Ser Thr Gly Ser Leu Leu Gly Asp 
    290                 295                 300


Pro Ala Ala Ser Ser Pro Pro Gly Glu Arg Gly Arg Ser Ala Ser Pro 
305                 310                 315                 320


Pro Gln Lys Arg Leu Gln Pro Pro Asp Phe Ile Asp Pro Leu Ala Asn 
                325                 330                 335


Lys Lys Pro Arg Ile Ser His Phe Thr Gln Arg Ala Gln Pro Ala Val 
            340                 345                 350


Asn Gly Lys Leu Gly Val Pro Asn Gly Arg Glu Ala Leu Leu Pro Thr 
        355                 360                 365


Pro Gly Pro Pro Ala Ser Thr Asp Thr Leu Ser Ser Ser Thr His Leu 
    370                 375                 380


Pro Pro Arg Leu Glu Pro Pro Arg Ala His Asp Pro Leu Ala Asp Val 
385                 390                 395                 400


Ser Asn Asp Leu Gly His Ser Gly Arg Asp Cys Glu His Gly Glu Ala 
                405                 410                 415


Ala Ala Pro Ala Pro Thr Val Arg Leu Gly Leu Pro Leu Leu Thr Asp 
            420                 425                 430


Cys Ala Gln Pro Ser Arg Pro His Gly Ser Pro Ser Arg Ser Lys Pro 
        435                 440                 445


Lys Lys Lys Ser Lys Lys His Lys Asp Lys Glu Arg Ala Ala Glu Asp 
    450                 455                 460


Lys Pro Arg Ala Gln Leu Pro Asp Cys Ala Pro Ala Thr His Ala Thr 
465                 470                 475                 480


Pro Gly Ala Pro Ala Asp Thr Pro Gly Leu Asn Gly Thr Cys Ser Val 
                485                 490                 495


Ser Ser Val Pro Thr Ser Thr Ser Glu Thr Pro Asp Tyr Leu Leu Lys 
            500                 505                 510


Tyr Ala Ala Ile Ser Ser Ser Glu Gln Arg Gln Ser Tyr Lys Asn Asp 
        515                 520                 525


Phe Asn Ala Glu Tyr Ser Glu Tyr Arg Asp Leu His Ala Arg Ile Glu 
    530                 535                 540


Arg Ile Thr Arg Arg Phe Thr Gln Leu Asp Ala Gln Leu Arg Gln Leu 
545                 550                 555                 560


Ser Gln Gly Ser Glu Glu Tyr Glu Thr Thr Arg Gly Gln Ile Leu Gln 
                565                 570                 575


Glu Tyr Arg Lys Ile Lys Lys Thr Asn Thr Asn Tyr Ser Gln Glu Lys 
            580                 585                 590


His Arg Cys Glu Tyr Leu His Ser Lys Leu Ala His Ile Lys Arg Leu 
        595                 600                 605


Ile Ala Glu Tyr Asp Gln Arg Gln Leu Gln Ala Trp Pro 
    610                 615                 620


<210>  9212
<211>  2295
<212>  DNA
<213>  Homo sapiens

<400>  9212
ggcggggcgg ggcgtggccg gcgtggcggc gctggagccg ggaagggggc gcgggggaga     60

gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg    120

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    180

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    240

caaggaagcc aagggcacat ctccatcccc cagcctgact gccccgcaga ggcgcggacg    300

ttctccttct acctctccaa catcggccgc gacaaccccc agggcagctt cgactgcatc    360

cagcagtatg tctccagtca tggggaagtt cacctggact gcctgggcag catacaggac    420

aagatcacgg tgtgtgccac cgacgactcc taccagaagg cgcggcagag catggcccag    480

gcggaggagg agacgcggag ccgaagtgcc attgtcatca aggctggagg ccgctacctg    540

ggcaagaagg ttcagtttcg gaaaccagcc ccaggtgcaa cagacgcggt gccctcccgg    600

aagcgggcaa cccccatcaa cttggcgagt gccatcagga agagtggtgc cagtgccgtg    660

agtgggggca gcggggtgtc ccagaggccc ttccgtgacc gagtgctgca cctcctggca    720

ctacggccct accgcaaggc tgagctgctg ctgcgactgc agaaggacgg cctgacgcag    780

gcggacaagg acgcgctgga tggcctcctc cagcaggtgg ccaacatgag tgctaaggac    840

ggcacgtgta cactgcagga ctgcatgtac aaggatgtgc agaaggactg gcctggctac    900

tcggaggggg accagcagct gctgaagcgg gtgctcgtcc ggaagctgtg ccagccacag    960

agcactggca gcctccttgg agaccctgct gcctccagcc ccccaggcga gcgtgggcgc   1020

tcggcctcgc ccccacagaa gcggctgcag cctcctgatt tcatcgaccc cctagccaac   1080

aagaaacccc ggatatcgca cttcactcag agagctcagc ctgccgtcaa cgggaagctg   1140

ggcgtgccca atggccgtga ggccttgctg cccaccccgg gcccaccagc cagcacggac   1200

accctcagct ccagcactca cctgcccccg cggctggagc ccccgagggc ccacgacccc   1260

ctggccgatg tcagcaatga cctgggccac agcggccgag actgtgagca cggagaggcg   1320

gctgccccag cccccactgt gcgcctcggc ctgcccctgc tgacggactg tgcccagccc   1380

agcaggccac acggcagccc ctcgcgcagc aagcccaaga agaagtccaa gaagcacaaa   1440

gacaaggaga gggcggctga ggacaagccc cgggcccagc ttccagactg tgcacctgcc   1500

acccatgcca cccccggagc cccagcagac accccaggtt taaacggaac ctgcagcgtt   1560

tccagtgttc ccacgtccac gtcggagacg cctgactact tgctgaagta cgcagccatc   1620

tcctcttcgg agcagcgcca gagctacaag aacgacttca atgccgagta cagcgagtac   1680

cgcgacctgc acgcccgcat tgagcgcatc acgcggcggt tcacccagct cgacgcccag   1740

ctccggcagc tctcccaggg ctccgaggag tatgagacta ctcgagggca gattttgcag   1800

gaatatcgaa aaatcaaaaa gaccaacacc aactacagcc aggagaagca ccgctgcgag   1860

tacctgcaca gcaagctggc ccacatcaag aggctcatcg ccgagtacga ccagcggcag   1920

ctgcaggctt ggccctagcc gccctccccg atggcgggga tctgggaggg tcgggggagc   1980

aaaaggcggt gagagaggat ttatttaaaa aaataaaccc gaggaagatg ctcatctgag   2040

ccagcaccgc cggctttcag ggcagcccct gcagacgtct ggccctggcg ggtggctgca   2100

agcccacctc ggccctccct gcgcttcctg agcagtccct gcttatgatg ggctccccag   2160

gaagcccact gcctcctccc tggctgcagc ctccggggtt cagcctcctg tctcgccaga   2220

agactcctag gcccttgggg tggcgcgcct gccttttcta gttttataca aagacagcca   2280

cttttagcta ctgct                                                    2295


<210>  9213
<211>  621
<212>  PRT
<213>  Homo sapiens

<400>  9213

Met Ala Ala Leu Lys Glu Asp Arg Ser Tyr Gly Leu Ser Cys Gly Arg 
1               5                   10                  15


Val Ser Asp Gly Ser Lys Val Ser Val Phe His Val Lys Leu Thr Asp 
            20                  25                  30


Ser Ala Leu Arg Ala Phe Glu Ser Tyr Arg Ala Arg Gln Asp Ser Val 
        35                  40                  45


Ser Leu Arg Pro Ser Ile Arg Phe Gln Gly Ser Gln Gly His Ile Ser 
    50                  55                  60


Ile Pro Gln Pro Asp Cys Pro Ala Glu Ala Arg Thr Phe Ser Phe Tyr 
65                  70                  75                  80


Leu Ser Asn Ile Gly Arg Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile 
                85                  90                  95


Gln Gln Tyr Val Ser Ser His Gly Glu Val His Leu Asp Cys Leu Gly 
            100                 105                 110


Ser Ile Gln Asp Lys Ile Thr Val Cys Ala Thr Asp Asp Ser Tyr Gln 
        115                 120                 125


Lys Ala Arg Gln Ser Met Ala Gln Ala Glu Glu Glu Thr Arg Ser Arg 
    130                 135                 140


Ser Ala Ile Val Ile Lys Ala Gly Gly Arg Tyr Leu Gly Lys Lys Val 
145                 150                 155                 160


Gln Phe Arg Lys Pro Ala Pro Gly Ala Thr Asp Ala Val Pro Ser Arg 
                165                 170                 175


Lys Arg Ala Thr Pro Ile Asn Leu Ala Ser Ala Ile Arg Lys Ser Gly 
            180                 185                 190


Ala Ser Ala Val Ser Gly Gly Ser Gly Val Ser Gln Arg Pro Phe Arg 
        195                 200                 205


Asp Arg Val Leu His Leu Leu Ala Leu Arg Pro Tyr Arg Lys Ala Glu 
    210                 215                 220


Leu Leu Leu Arg Leu Gln Lys Asp Gly Leu Thr Gln Ala Asp Lys Asp 
225                 230                 235                 240


Ala Leu Asp Gly Leu Leu Gln Gln Val Ala Asn Met Ser Ala Lys Asp 
                245                 250                 255


Gly Thr Cys Thr Leu Gln Asp Cys Met Tyr Lys Asp Val Gln Lys Asp 
            260                 265                 270


Trp Pro Gly Tyr Ser Glu Gly Asp Gln Gln Leu Leu Lys Arg Val Leu 
        275                 280                 285


Val Arg Lys Leu Cys Gln Pro Gln Ser Thr Gly Ser Leu Leu Gly Asp 
    290                 295                 300


Pro Ala Ala Ser Ser Pro Pro Gly Glu Arg Gly Arg Ser Ala Ser Pro 
305                 310                 315                 320


Pro Gln Lys Arg Leu Gln Pro Pro Asp Phe Ile Asp Pro Leu Ala Asn 
                325                 330                 335


Lys Lys Pro Arg Ile Ser His Phe Thr Gln Arg Ala Gln Pro Ala Val 
            340                 345                 350


Asn Gly Lys Leu Gly Val Pro Asn Gly Arg Glu Ala Leu Leu Pro Thr 
        355                 360                 365


Pro Gly Pro Pro Ala Ser Thr Asp Thr Leu Ser Ser Ser Thr His Leu 
    370                 375                 380


Pro Pro Arg Leu Glu Pro Pro Arg Ala His Asp Pro Leu Ala Asp Val 
385                 390                 395                 400


Ser Asn Asp Leu Gly His Ser Gly Arg Asp Cys Glu His Gly Glu Ala 
                405                 410                 415


Ala Ala Pro Ala Pro Thr Val Arg Leu Gly Leu Pro Leu Leu Thr Asp 
            420                 425                 430


Cys Ala Gln Pro Ser Arg Pro His Gly Ser Pro Ser Arg Ser Lys Pro 
        435                 440                 445


Lys Lys Lys Ser Lys Lys His Lys Asp Lys Glu Arg Ala Ala Glu Asp 
    450                 455                 460


Lys Pro Arg Ala Gln Leu Pro Asp Cys Ala Pro Ala Thr His Ala Thr 
465                 470                 475                 480


Pro Gly Ala Pro Ala Asp Thr Pro Gly Leu Asn Gly Thr Cys Ser Val 
                485                 490                 495


Ser Ser Val Pro Thr Ser Thr Ser Glu Thr Pro Asp Tyr Leu Leu Lys 
            500                 505                 510


Tyr Ala Ala Ile Ser Ser Ser Glu Gln Arg Gln Ser Tyr Lys Asn Asp 
        515                 520                 525


Phe Asn Ala Glu Tyr Ser Glu Tyr Arg Asp Leu His Ala Arg Ile Glu 
    530                 535                 540


Arg Ile Thr Arg Arg Phe Thr Gln Leu Asp Ala Gln Leu Arg Gln Leu 
545                 550                 555                 560


Ser Gln Gly Ser Glu Glu Tyr Glu Thr Thr Arg Gly Gln Ile Leu Gln 
                565                 570                 575


Glu Tyr Arg Lys Ile Lys Lys Thr Asn Thr Asn Tyr Ser Gln Glu Lys 
            580                 585                 590


His Arg Cys Glu Tyr Leu His Ser Lys Leu Ala His Ile Lys Arg Leu 
        595                 600                 605


Ile Ala Glu Tyr Asp Gln Arg Gln Leu Gln Ala Trp Pro 
    610                 615                 620


<210>  9214
<211>  2045
<212>  DNA
<213>  Homo sapiens

<400>  9214
ggcggggcgg ggcgtggccg gcgtggcggc gctggagccg ggaagggggc gcgggggaga     60

gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg    120

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    180

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    240

caaggaagcc aagggcacat ctccatcccc cagcctgact gccccgcaga ggcgcggacg    300

ttctccttct acctctccaa catcggccgc gacaaccccc agggcagctt cgactgcatc    360

cagcagtatg tctccagtca tggggaagtt cacctggact gcctgggcag catacaggac    420

aagatcacgg tgtgtgccac cgacgactcc taccagaagg cgcggcagag catggcccag    480

gcggaggagg agacgcggag ccgaagtgcc attgtcatca aggctggagg ccgctacctg    540

ggcaagaagg ttcagtttcg gaaaccagcc ccaggtgcaa cagacgcggt gccctcccgg    600

aagcgggcaa cccccatcaa cttggcgagt gccatcagga agagtggtgc cagtgccgtg    660

agtgggggca gcggggtgtc ccagaggccc ttccgtgacc gagtgctgca cctcctggca    720

ctacggccct accgcaaggc tgagctgctg ctgcgactgc agaaggacgg cctgacgcag    780

gcggacaagg acgcgctgga tggcctcctc cagcaggtgg ccaacatgag tgctaaggac    840

ggcacgtgta cactgcagga ctgcatgtac aaggatgtgc agaaggactg gcctggctac    900

tcggaggggg accagcagct gctgaagcgg gtgctcgtcc ggaagctgtg ccagccacag    960

agcactggca gcctccttgg agaccctgct gcctccagcc ccccaggcga gcgtgggcgc   1020

tcggcctcgc ccccacagaa gcggctgcag cctcctgatt tcatcgaccc cctagccaac   1080

aagaaacccc ggatatcgca cttcactcag agagctcagc ctgccgtcaa cgggaagctg   1140

ggcgtgccca atggccgtga ggccttgctg cccaccccgg gcccaccagc cagcacggac   1200

accctcagct ccagcactca cctgcccccg cggctggagc ccccgagggc ccacgacccc   1260

ctggccgatg tcagcaatga cctgggccac agcggccgag actgtgagca cggagaggcg   1320

gctgccccag cccccactgt gcgcctcggc ctgcccctgc tgacggactg tgcccagccc   1380

agcaggccac acggcagccc ctcgcgcagc aagcccaaga agaagtccaa gaagcacaaa   1440

gacaaggaga gggcggctga ggacaagccc cgggcccagc ttccagactg tgcacctgcc   1500

acccatgcca cccccggagc cccagcagac accccaggtt taaacggaac ctgcagcgtt   1560

tccagtgttc ccacgtccac gtcggagacg cctgactact tgctgaagta cgcagccatc   1620

tcctcttcgg agcagcgcca gagctacaag aacgacttca atgccgagta cagcgagtac   1680

cgcgacctgc acgcccgcat tgagcgcatc acgcggcggt tcacccagct cgacgcccag   1740

ctccggcagc tctcccaggg ctccgaggag tatgagacta ctcgagggca gattttgcag   1800

gaatatcgaa aaatcaaaaa gaccaacacc aactacagcc aggagaagca ccgctgcgag   1860

tacctgcaca gcaagctggc ccacatcaag aggctcatcg ccgagtacga ccagcggcag   1920

ctgcaggctt ggccctagcc gccctccccg atggcgggga tctgggaggg tcgggggagc   1980

aaaaggcggt gagagaggat ttatttaaaa aaataaaccc gaggaagatg ctcatctgag   2040

ccagc                                                               2045


<210>  9215
<211>  621
<212>  PRT
<213>  Homo sapiens

<400>  9215

Met Ala Ala Leu Lys Glu Asp Arg Ser Tyr Gly Leu Ser Cys Gly Arg 
1               5                   10                  15


Val Ser Asp Gly Ser Lys Val Ser Val Phe His Val Lys Leu Thr Asp 
            20                  25                  30


Ser Ala Leu Arg Ala Phe Glu Ser Tyr Arg Ala Arg Gln Asp Ser Val 
        35                  40                  45


Ser Leu Arg Pro Ser Ile Arg Phe Gln Gly Ser Gln Gly His Ile Ser 
    50                  55                  60


Ile Pro Gln Pro Asp Cys Pro Ala Glu Ala Arg Thr Phe Ser Phe Tyr 
65                  70                  75                  80


Leu Ser Asn Ile Gly Arg Asp Asn Pro Gln Gly Ser Phe Asp Cys Ile 
                85                  90                  95


Gln Gln Tyr Val Ser Ser His Gly Glu Val His Leu Asp Cys Leu Gly 
            100                 105                 110


Ser Ile Gln Asp Lys Ile Thr Val Cys Ala Thr Asp Asp Ser Tyr Gln 
        115                 120                 125


Lys Ala Arg Gln Ser Met Ala Gln Ala Glu Glu Glu Thr Arg Ser Arg 
    130                 135                 140


Ser Ala Ile Val Ile Lys Ala Gly Gly Arg Tyr Leu Gly Lys Lys Val 
145                 150                 155                 160


Gln Phe Arg Lys Pro Ala Pro Gly Ala Thr Asp Ala Val Pro Ser Arg 
                165                 170                 175


Lys Arg Ala Thr Pro Ile Asn Leu Ala Ser Ala Ile Arg Lys Ser Gly 
            180                 185                 190


Ala Ser Ala Val Ser Gly Gly Ser Gly Val Ser Gln Arg Pro Phe Arg 
        195                 200                 205


Asp Arg Val Leu His Leu Leu Ala Leu Arg Pro Tyr Arg Lys Ala Glu 
    210                 215                 220


Leu Leu Leu Arg Leu Gln Lys Asp Gly Leu Thr Gln Ala Asp Lys Asp 
225                 230                 235                 240


Ala Leu Asp Gly Leu Leu Gln Gln Val Ala Asn Met Ser Ala Lys Asp 
                245                 250                 255


Gly Thr Cys Thr Leu Gln Asp Cys Met Tyr Lys Asp Val Gln Lys Asp 
            260                 265                 270


Trp Pro Gly Tyr Ser Glu Gly Asp Gln Gln Leu Leu Lys Arg Val Leu 
        275                 280                 285


Val Arg Lys Leu Cys Gln Pro Gln Ser Thr Gly Ser Leu Leu Gly Asp 
    290                 295                 300


Pro Ala Ala Ser Ser Pro Pro Gly Glu Arg Gly Arg Ser Ala Ser Pro 
305                 310                 315                 320


Pro Gln Lys Arg Leu Gln Pro Pro Asp Phe Ile Asp Pro Leu Ala Asn 
                325                 330                 335


Lys Lys Pro Arg Ile Ser His Phe Thr Gln Arg Ala Gln Pro Ala Val 
            340                 345                 350


Asn Gly Lys Leu Gly Val Pro Asn Gly Arg Glu Ala Leu Leu Pro Thr 
        355                 360                 365


Pro Gly Pro Pro Ala Ser Thr Asp Thr Leu Ser Ser Ser Thr His Leu 
    370                 375                 380


Pro Pro Arg Leu Glu Pro Pro Arg Ala His Asp Pro Leu Ala Asp Val 
385                 390                 395                 400


Ser Asn Asp Leu Gly His Ser Gly Arg Asp Cys Glu His Gly Glu Ala 
                405                 410                 415


Ala Ala Pro Ala Pro Thr Val Arg Leu Gly Leu Pro Leu Leu Thr Asp 
            420                 425                 430


Cys Ala Gln Pro Ser Arg Pro His Gly Ser Pro Ser Arg Ser Lys Pro 
        435                 440                 445


Lys Lys Lys Ser Lys Lys His Lys Asp Lys Glu Arg Ala Ala Glu Asp 
    450                 455                 460


Lys Pro Arg Ala Gln Leu Pro Asp Cys Ala Pro Ala Thr His Ala Thr 
465                 470                 475                 480


Pro Gly Ala Pro Ala Asp Thr Pro Gly Leu Asn Gly Thr Cys Ser Val 
                485                 490                 495


Ser Ser Val Pro Thr Ser Thr Ser Glu Thr Pro Asp Tyr Leu Leu Lys 
            500                 505                 510


Tyr Ala Ala Ile Ser Ser Ser Glu Gln Arg Gln Ser Tyr Lys Asn Asp 
        515                 520                 525


Phe Asn Ala Glu Tyr Ser Glu Tyr Arg Asp Leu His Ala Arg Ile Glu 
    530                 535                 540


Arg Ile Thr Arg Arg Phe Thr Gln Leu Asp Ala Gln Leu Arg Gln Leu 
545                 550                 555                 560


Ser Gln Gly Ser Glu Glu Tyr Glu Thr Thr Arg Gly Gln Ile Leu Gln 
                565                 570                 575


Glu Tyr Arg Lys Ile Lys Lys Thr Asn Thr Asn Tyr Ser Gln Glu Lys 
            580                 585                 590


His Arg Cys Glu Tyr Leu His Ser Lys Leu Ala His Ile Lys Arg Leu 
        595                 600                 605


Ile Ala Glu Tyr Asp Gln Arg Gln Leu Gln Ala Trp Pro 
    610                 615                 620


<210>  9216
<211>  452
<212>  DNA
<213>  Homo sapiens

<400>  9216
ctgtgcacct gccacccatg ccacccccgg agccccagca gacaccccag gtttaaacgg     60

aacctgcagc gtttccagtg ttcccacgtc cacgtcggag acgcctgact acttgctgaa    120

gtacgcagcc atctcctctt cggagcagcg ccagagctac aagaacgact tcaatgccga    180

gtacagcgag taccgcgacc tgcacgcccg cattgagcgc atcacgcggc ggttcaccca    240

gctcgacgcc cagctccggc agctctccca gggctccgag gagtatgagg tagagccccc    300

ccgctgccta ctgtgccctg gctctggcgg gagccagggc ccacttgggc gcgcaccatc    360

gccaccacga gcttggtggc cccagagtct ggcccttccc caggcagcgc ttctccccct    420

ggtgcactcc atgcagcaac cccatggttc tg                                  452


<210>  9217
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  9217

Met Pro Ser Thr Ala Ser Thr Ala Thr Cys Thr Pro Ala Leu Ser Ala 
1               5                   10                  15


Ser Arg Gly Gly Ser Pro Ser Ser Thr Pro Ser Ser Gly Ser Ser Pro 
            20                  25                  30


Arg Ala Pro Arg Ser Met Arg 
        35


<210>  9218
<211>  448
<212>  DNA
<213>  Homo sapiens

<400>  9218
gtgtattgag gatacatctg aaattgataa aatcatttct gtatcggaaa gaaagccact     60

gcaagaaggt ctagaaaacg cactaaattg tagttgtggt cttaggcgac gcgcacttca    120

gtcttcctgc ccctcccctc cccctgaagg ggcgaagggc tgagcgtcat catggacact    180

ttgctcatgg atggccgatt ggggtggccc atgggctcct ctggctggcc ctgtcctgga    240

gctgccttgt ggagcgtgca attcagtgtc tagtggaaag gacgggatga tctgggtggg    300

gcacagacca agggcgtgga actttgtcag cagcaagaga tgcaggccct gctggccatc    360

ttgtctttgt cctgtctggc cagagactgg gatgccccag agactcaggt caagccaggg    420

gtcatttgtt ttcagcttag tgaccttt                                       448


<210>  9219
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  9219

Met Ala Asp Trp Gly Gly Pro Trp Ala Pro Leu Ala Gly Pro Val Leu 
1               5                   10                  15


Glu Leu Pro Cys Gly Ala Cys Asn Ser Val Ser Ser Gly Lys Asp Gly 
            20                  25                  30


Met Ile Trp Val Gly His Arg Pro Arg Ala Trp Asn Phe Val Ser Ser 
        35                  40                  45


Lys Arg Cys Arg Pro Cys Trp Pro Ser Cys Leu Cys Pro Val Trp Pro 
    50                  55                  60


Glu Thr Gly Met Pro Gln Arg Leu Arg Ser Ser Gln Gly Ser Phe Val 
65                  70                  75                  80


Phe Ser Leu Val Thr 
                85


<210>  9220
<211>  969
<212>  DNA
<213>  Homo sapiens

<400>  9220
gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg     60

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    120

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    180

caaggaagcc aagggtcatg gggaagttca cctggactgc ctgggcagca tacaggacaa    240

gatcacggtg tgtgccaccg acgactccta ccagaaggcg cggcagagca tggcccaggc    300

ggaggaggag acgcggagcc gaagtgccat tgtcatcaag gctggaggcc gctacctggg    360

caagaaggtt cagtttcgga aaccagcccc aggtgcaaca gacgcggtgc cctcccggaa    420

gcgggcaacc cccatcaact tggcgagtgc catcaggaag agtggtgcca gtgccgtgag    480

tgggggcagc ggggtgtccc agaggccctt ccgtgaccga gtgctgcacc tcctggcact    540

acggccctac cgcaaggctg agctgctgct gcgactgcag aaggacggcc tgacgcaggc    600

ggacaaggac gcgctggatg gcctcctcca gcaggtgggt gccgccccga tgtcttgtct    660

ttaccagtgg tctccgcaga tggtcttgtg cgggtgggat gggccagagc atggagactg    720

ggattgggac tggcaaggaa gagcccttcc tggggtctct cacaggttca gaacctgcct    780

gagagccagg gcctcctgga ttagaacaag cttagggggc catggatgcg tttctgggca    840

tggccccgac tgtccagggt tgagaggtgg actcagcatg gagcccaggc cctccttcac    900

tgtctgctga cacacgggcc gtggggcctg gcacagtgga ttcaggcttc agttgcagac    960

gatttgtgg                                                            969


<210>  9221
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  9221

Met Ala Gln Ala Glu Glu Glu Thr Arg Ser Arg Ser Ala Ile Val Ile 
1               5                   10                  15


Lys Ala Gly Gly Arg Tyr Leu Gly Lys Lys Val Gln Phe Arg Lys Pro 
            20                  25                  30


Ala Pro Gly Ala Thr Asp Ala Val Pro Ser Arg Lys Arg Ala Thr Pro 
        35                  40                  45


Ile Asn Leu Ala Ser Ala Ile Arg Lys Ser Gly Ala Ser Ala Val Ser 
    50                  55                  60


Gly Gly Ser Gly Val Ser Gln Arg Pro Phe Arg Asp Arg Val Leu His 
65                  70                  75                  80


Leu Leu Ala Leu Arg Pro Tyr Arg Lys Ala Glu Leu Leu Leu Arg Leu 
                85                  90                  95


Gln Lys Asp Gly Leu Thr Gln Ala Asp Lys Asp Ala Leu Asp Gly Leu 
            100                 105                 110


Leu Gln Gln Val Gly Ala Ala Pro Met Ser Cys Leu Tyr Gln Trp Ser 
        115                 120                 125


Pro Gln Met Val Leu Cys Gly Trp Asp Gly Pro Glu His Gly Asp Trp 
    130                 135                 140


Asp Trp Asp Trp Gln Gly Arg Ala Leu Pro Gly Val Ser His Arg Phe 
145                 150                 155                 160


Arg Thr Cys Leu Arg Ala Arg Ala Ser Trp Ile Arg Thr Ser Leu Gly 
                165                 170                 175


Gly His Gly Cys Val Ser Gly His Gly Pro Asp Cys Pro Gly Leu Arg 
            180                 185                 190


Gly Gly Leu Ser Met Glu Pro Arg Pro Ser Phe Thr Val Cys 
        195                 200                 205


<210>  9222
<211>  623
<212>  DNA
<213>  Homo sapiens

<400>  9222
gatggtcgca agatggcggc gctgaaggag gataggagct acgggctgtc gtgcgggcgg     60

gttagcgacg gcagcaaggt gtcggtgttc cacgtgaagc tcaccgacag tgccctgagg    120

gccttcgaga gctaccgcgc cagacaggat tctgtttcac tgaggccatc tatccgattt    180

caaggaagcc aaggggtaag tttttgtctt aatcattcat atttggaatc ttgggactgg    240

tatagtctca ggtctgtcct tgctcgctgg gtacagcagc agctcatggc agtgtttggg    300

ccctgtctgc caccatgcaa ggctgggttc taggccccca ggatagcccc ttggctgggg    360

ccacaccagg acgtgtcggg tgcacgtcac aggctgcttg ggcaatgggc ggctctcctc    420

tcccagtggc tcccttcatg cagcgatgtg cacctagctt ccactctgat agggcagggg    480

cccccaaccc ccagcactgg actggttagg aactgcccac acagcaggag gtgagctgtg    540

ggtgagtgag cacgaccacc tgagctctgc ctcctgtcag ctgagcctgt tattagattc    600

ttacaggagc gcgaacccta ttg                                            623


<210>  9223
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  9223

Met Ala Ala Leu Lys Glu Asp Arg Ser Tyr Gly Leu Ser Cys Gly Arg 
1               5                   10                  15


Val Ser Asp Gly Ser Lys Val Ser Val Phe His Val Lys Leu Thr Asp 
            20                  25                  30


Ser Ala Leu Arg Ala Phe Glu Ser Tyr Arg Ala Arg Gln Asp Ser Val 
        35                  40                  45


Ser Leu Arg Pro Ser Ile Arg Phe Gln Gly Ser Gln Gly Val Ser Phe 
    50                  55                  60


Cys Leu Asn His Ser Tyr Leu Glu Ser Trp Asp Trp Tyr Ser Leu Arg 
65                  70                  75                  80


Ser Val Leu Ala Arg Trp Val Gln Gln Gln Leu Met Ala Val Phe Gly 
                85                  90                  95


Pro Cys Leu Pro Pro Cys Lys Ala Gly Phe 
            100                 105


<210>  9224
<211>  1720
<212>  DNA
<213>  Homo sapiens

<400>  9224
gttacacctt ctctggtcag tctcacagct gcgcggtggc agacaggact tgttccacag     60

tggtaactgg gatagagctg atgtggcccc aaccccacct cccttcccgc cctgccatgt    120

cggaagaaac ccgacgagca aattggcagc agcaaagaaa aagttgagag actatcagtg    180

gaggaacagc cctggtgttc ctacaggagt gaaaaagaaa attaaaaatt gcagtaaccc    240

cgagacaacc acttctggtg gttgccactc acctggagat gtaatggagg catgtagaca    300

aatacaactg gagagagata catttgctga gattcttaaa ggagagagag ccacatggca    360

gcagaggatg aatcagatgt cggagcagat gcacacactg agggaggaga aggagtgtat    420

tatgaatcgg ttacaggagc tggagacaag cttggtggaa ttgagaaaac agatgactga    480

actcccagcc ctggcacccc cagcaaggcc ctccgaggtg gagcagcagc tacaagagga    540

ggctgagcac ctgagggagg agctggagag tctggcagga cagctccaag cccaggagca    600

cctggaagct gccagccaga gaaccagcag ctacaggccc agctgagcct catggctctc    660

cctgaggaag gtacgggaga tcactcagag gaagaggagg gagcccagga ggaagggggg    720

actgttagca gataggagtg aggagtttag aacagctggt ttacagctgc tcattcccct    780

ctggagaggg actggcccag ggttatacag tgacggttga ggcagaggtg ggcccaccct    840

acttcccttg ttgggtcgcg tgaggacccc tctagctctg tgccctagga ggtagactgg    900

acggagggtc gtctcggccc atgaagagca tcctgcagga cctggaaagc caggagtcca    960

tggtggcatt tttaacatca gctgtagcca gtgcagatgg ggagcaggct cggctccgtg   1020

ggcagctgaa ggagcaaagg ctgcgctgcc ggtgcctggc tcacctgctg gcctgggccc   1080

agaagcagcc agaggcagca gccccagccc cagggactgg gatggattct gtgtgtgggg   1140

ggacccaccg ggccctgcag ggtgccatgg agaaactgca gagctgcttt atgcagctga   1200

tgcaggaaaa ggtggacctg aaagagcggg tggaggagct ggaacatcgc tgcatccagc   1260

tctctggaga gacagacacc atcggagtct acactgccct ctctcagcca gggggcagcg   1320

ctgaaggagc agcaccgaga ggaggaggag cacatccaca ggctagccca ggacaaggag   1380

gagatgaaga tctttgccag gtgaccctca ccagcagcgt ggagcctgca caaggagagg   1440

ccggggaggg ttctcccctc gacaacccca gtgcacagca gatcatgcag ctgtttggtg   1500

agatgcagaa ccctcaggag cgcccaggct tgggcagcat cccctgcatt ctgttttccc   1560

accaggctga caaaaaccac caggtgaaga tcaccctcat ctgaaagcca gttgccttca   1620

gcaaagccag gagaaggggg gtgggaggct ccgccccccc atgtccctcc cacccctttg   1680

cagtcacccc tttaccctta aagtaaatgg atttagccat                         1720


<210>  9225
<211>  227
<212>  PRT
<213>  Homo sapiens

<400>  9225

Met Lys Ser Ile Leu Gln Asp Leu Glu Ser Gln Glu Ser Met Val Ala 
1               5                   10                  15


Phe Leu Thr Ser Ala Val Ala Ser Ala Asp Gly Glu Gln Ala Arg Leu 
            20                  25                  30


Arg Gly Gln Leu Lys Glu Gln Arg Leu Arg Cys Arg Cys Leu Ala His 
        35                  40                  45


Leu Leu Ala Trp Ala Gln Lys Gln Pro Glu Ala Ala Ala Pro Ala Pro 
    50                  55                  60


Gly Thr Gly Met Asp Ser Val Cys Gly Gly Thr His Arg Ala Leu Gln 
65                  70                  75                  80


Gly Ala Met Glu Lys Leu Gln Ser Cys Phe Met Gln Leu Met Gln Glu 
                85                  90                  95


Lys Val Asp Leu Lys Glu Arg Val Glu Glu Leu Glu His Arg Cys Ile 
            100                 105                 110


Gln Leu Ser Gly Glu Thr Asp Thr Ile Gly Val Tyr Thr Ala Leu Ser 
        115                 120                 125


Gln Pro Gly Gly Ser Ala Glu Gly Ala Ala Pro Arg Gly Gly Gly Ala 
    130                 135                 140


His Pro Gln Ala Ser Pro Gly Gln Gly Gly Asp Glu Asp Leu Cys Gln 
145                 150                 155                 160


Val Thr Leu Thr Ser Ser Val Glu Pro Ala Gln Gly Glu Ala Gly Glu 
                165                 170                 175


Gly Ser Pro Leu Asp Asn Pro Ser Ala Gln Gln Ile Met Gln Leu Phe 
            180                 185                 190


Gly Glu Met Gln Asn Pro Gln Glu Arg Pro Gly Leu Gly Ser Ile Pro 
        195                 200                 205


Cys Ile Leu Phe Ser His Gln Ala Asp Lys Asn His Gln Val Lys Ile 
    210                 215                 220


Thr Leu Ile 
225


<210>  9226
<211>  652
<212>  DNA
<213>  Homo sapiens

<400>  9226
agtctcacag ctgcgcggtg gcagacagga cttgttccac agtggtaact gggatagagc     60

tgatgtggcc ccaaccccac ctcccttccc gccctgccat gtcggaagaa acccgacgag    120

caaattggca gcagcaaaga aaaagttgag agactatcag tggaggaaca gccctggtgt    180

tcctacagga gtgaaaaaga aaattaaaaa ttgcagtaac cccgagacaa ccacttctgg    240

tggttgccac tcacctggag atgtaatgga ggcatgtaga caaatacaac tggagagaga    300

tacatttgct gagattctta aaggagagag agccacatgg cagcagagga tgaatcagat    360

gtcggagcag ctgaactccc agccctggca cccccagcaa ggccctccga ggtggagcag    420

cagctacaag aggaggctga gcacctgagg gaggagctgg agagtctggc aggacagctc    480

caagcccagg agcacctgga agctgccagc cagagaacca gcagctacag gcccagctga    540

gcctcatggc tctccctgag gaaggtacgg gagatcactc agaggaagag gagggagccc    600

aggaggaagg ggggactgtt agcagatagg agtgaggagt ttagaacagc tg            652


<210>  9227
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  9227

Met Ala Ala Glu Asp Glu Ser Asp Val Gly Ala Ala Glu Leu Pro Ala 
1               5                   10                  15


Leu Ala Pro Pro Ala Arg Pro Ser Glu Val Glu Gln Gln Leu Gln Glu 
            20                  25                  30


Glu Ala Glu His Leu Arg Glu Glu Leu Glu Ser Leu Ala Gly Gln Leu 
        35                  40                  45


Gln Ala Gln Glu His Leu Glu Ala Ala Ser Gln Arg Thr Ser Ser Tyr 
    50                  55                  60


Arg Pro Ser 
65


<210>  9228
<211>  1110
<212>  DNA
<213>  Homo sapiens

<400>  9228
ggttggcagc ctggagtctg gagtgcaggt gccgggcagg cagcactggg agcgctcggc     60

gacttggctg gaggccgaag gtgccgcccc tcggggacca gagcgtcttt gcaagcgtgg    120

ttggggaact ccagagtccc acatcacagt tcagcatgtg cctcaggagc ttcagcaagt    180

ctttcgtgga aggagagtct gccggtgacg ggggaagcag gccatcagcc cgcccagctt    240

catctcaggc cgcttccaac accgccaagc aaactccctt ggcaagatcc atgcaaggcc    300

gcggctgacc accgggaggc agcagcctac tctgcaaggc actttcttta cccgaccccc    360

accccctttt aacaggtggc aggaaacctg ctggcccagc catctgccgc acccaccctt    420

cactcccagt cccatctccc catagcacag atttccctat catgagccct gacgtgacct    480

gggtgtcctc ttgccttcct ctgcccaagg aattcctaca gagattcttt ctctatcctc    540

ctttgtacat ttccaaggaa ttgtttcccc agggcccctc cccttgaaga aattagacag    600

gaagctggag tagatggttc cctctttccc acctctcaca ctcccaagct ctggttaact    660

ctctgtgggc cagtggctag attccccaac acagatgaca actgaacaat acacatgcag    720

cgtaagaatg ttgtcgctgc caccagccac ttacagatac accattgcta aggtccaccc    780

aactggactg tttccccctc ccatagacta agccccaaag gccaaaaagt aaaacccgct    840

accccaaacc tgcctgtaac tgtttgacca gaggccagct gtcccaggat gcggttaaga    900

cgtctacttt gcacaagaga actggcaaga aaaacatctc caggaagcgg tcagacacat    960

ggcacaaagg accccccccc ttttcttttt ccttcaccct gatccagttc tatgtcctat   1020

aaaaccttgc tctagcctat aagtggggct gccttctctg cttttgtcaa gaggtagcca   1080

ggcaggactg acaataaatc agcttgcctg                                    1110


<210>  9229
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  9229

Met Cys Leu Arg Ser Phe Ser Lys Ser Phe Val Glu Gly Glu Ser Ala 
1               5                   10                  15


Gly Asp Gly Gly Ser Arg Pro Ser Ala Arg Pro Ala Ser Ser Gln Ala 
            20                  25                  30


Ala Ser Asn Thr Ala Lys Gln Thr Pro Leu Ala Arg Ser Met Gln Gly 
        35                  40                  45


Arg Gly 
    50


<210>  9230
<211>  423
<212>  DNA
<213>  Homo sapiens

<400>  9230
ctggagtgca ggtgccgggc aggcagcact gggagcgctc ggcgacttgg ctggaggccg     60

aaggtgccgc ccctcgggga ccagagcgtc tttgcaagcc catagaagaa acagtgaaga    120

gtaagaggaa aaggctgcca gaaggggagt ctcacaacag gaagaagtaa cagctacgca    180

tagaggaagg gaagctgttc aagagcgggc ccaggaacac aacacagaac cattgtcgtg    240

gttggggaac tccagagtcc cacatcacag ttcagcatgt gcctcaggag cttcagcaag    300

tctttcgtgg aaggagagtc tgccggtgac gggggaagca ggccatcagc ccgcccagct    360

tcatctcagg ccgcttccaa caccgccaag caaactccct tggcaagatc catgcaaggc    420

cgc                                                                  423


<210>  9231
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  9231

Met Cys Leu Arg Ser Phe Ser Lys Ser Phe Val Glu Gly Glu Ser Ala 
1               5                   10                  15


Gly Asp Gly Gly Ser Arg Pro Ser Ala Arg Pro Ala Ser Ser Gln Ala 
            20                  25                  30


Ala Ser Asn Thr Ala Lys Gln Thr Pro Leu Ala Arg Ser Met Gln Gly 
        35                  40                  45


<210>  9232
<211>  1095
<212>  DNA
<213>  Homo sapiens

<400>  9232
gtctttgtct ctcgctgcag tcggagtatg gtctagtgtt cgctgttctg cgtcctctgg     60

tcctagaggc ccatcctctg tggccctgtg acctgcaggt attgggagat ccacagctaa    120

gacgctagga ccccctggaa gcctagaaac gggagtgttg acatttaggg atgtggccat    180

agaattctct ctggaggagt ggcaatgcct ggacaccgca cagcagaatt tatataggaa    240

tgtgatgtta gagaactaca gaaacctggt cttcgtgggt attgctgcct ctaagccaga    300

cctgatcacc tgtctggagc aaggaaaaga accttggaat gtgaagagac atgagatggt    360

agctgaaccc ccagttgtat gttcttattt tgcccgagac ctttggccaa agcagggcaa    420

aaaaaattat ttccaaaaag tgatactgag aagatataaa aaatgtggat gtgaaaattt    480

acagttaaga aaatactgta aaagcatgga tgagtgtaag gtgcacaaag aatgttacaa    540

tggacttaac cagtgtttga cgactaccca gaacaaaata tttcaatgtg acaaatatgt    600

gaaagtcttt cataaatttt caaattcaaa cagacatacg ataagacata ctggaaagaa    660

atctttcaaa tgtaaagaat gtgaaaagtc attttgcatg ctttcacact tagctcaaca    720

taaaagaatt catagtggag agaaacccta caaatgtaaa gaatgtggga aagcctataa    780

tgagacctca aacctttcta cacataaaag aattcatact ggaaagaaac cctacaaatg    840

cgaagagtgt ggaaaagcct ttaaccggct ctcacacctt actacacata agataattca    900

tactggaaag aaaccctaca aatgtgagga gtgtggcaaa gcttttaacc aatctgcaaa    960

ccttactaca cataagagaa ttcatactgg agagaaaccc tacaaatgtg aagaatgtgg   1020

cagagctttt agccagtcct caacccttac tgcacataag ataattcatg ctggagagaa   1080

accttacaaa tgtga                                                    1095


<210>  9233
<211>  282
<212>  PRT
<213>  Homo sapiens

<400>  9233

Met Leu Glu Asn Tyr Arg Asn Leu Val Phe Val Gly Ile Ala Ala Ser 
1               5                   10                  15


Lys Pro Asp Leu Ile Thr Cys Leu Glu Gln Gly Lys Glu Pro Trp Asn 
            20                  25                  30


Val Lys Arg His Glu Met Val Ala Glu Pro Pro Val Val Cys Ser Tyr 
        35                  40                  45


Phe Ala Arg Asp Leu Trp Pro Lys Gln Gly Lys Lys Asn Tyr Phe Gln 
    50                  55                  60


Lys Val Ile Leu Arg Arg Tyr Lys Lys Cys Gly Cys Glu Asn Leu Gln 
65                  70                  75                  80


Leu Arg Lys Tyr Cys Lys Ser Met Asp Glu Cys Lys Val His Lys Glu 
                85                  90                  95


Cys Tyr Asn Gly Leu Asn Gln Cys Leu Thr Thr Thr Gln Asn Lys Ile 
            100                 105                 110


Phe Gln Cys Asp Lys Tyr Val Lys Val Phe His Lys Phe Ser Asn Ser 
        115                 120                 125


Asn Arg His Thr Ile Arg His Thr Gly Lys Lys Ser Phe Lys Cys Lys 
    130                 135                 140


Glu Cys Glu Lys Ser Phe Cys Met Leu Ser His Leu Ala Gln His Lys 
145                 150                 155                 160


Arg Ile His Ser Gly Glu Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys 
                165                 170                 175


Ala Tyr Asn Glu Thr Ser Asn Leu Ser Thr His Lys Arg Ile His Thr 
            180                 185                 190


Gly Lys Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Arg 
        195                 200                 205


Leu Ser His Leu Thr Thr His Lys Ile Ile His Thr Gly Lys Lys Pro 
    210                 215                 220


Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Gln Ser Ala Asn Leu 
225                 230                 235                 240


Thr Thr His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu 
                245                 250                 255


Glu Cys Gly Arg Ala Phe Ser Gln Ser Ser Thr Leu Thr Ala His Lys 
            260                 265                 270


Ile Ile His Ala Gly Glu Lys Pro Tyr Lys 
        275                 280


<210>  9234
<211>  3176
<212>  DNA
<213>  Homo sapiens

<400>  9234
cagttgtatg ttcttatttt gcccgagacc tttggccaaa gcagggcaaa aaaaattatt     60

tccaaaaagt gatactgaga agatataaaa aatgtggatg tgaaaattta cagttaagaa    120

aatactgtaa aagcatggat gagtgtaagg tgcacaaaga atgttacaat ggacttaacc    180

agtgtttgac gactacccag aacaaaatat ttcaatgtga caaatatgtg aaagtctttc    240

ataaattttc aaattcaaac agacatacga taagacatac tggaaagaaa tctttcaaat    300

gtaaagaatg tgaaaagtca ttttgcatgc tttcacactt agctcaacat aaaagaattc    360

atagtggaga gaaaccctac aaatgtaaag aatgtgggaa agcctataat gagacctcaa    420

acctttctac acataaaaga attcatactg gaaagaaacc ctacaaatgc gaagagtgtg    480

gaaaagcctt taaccggctc tcacacctta ctacacataa gataattcat actggaaaga    540

aaccctacaa atgtgaggag tgtggcaaag cttttaacca atctgcaaac cttactacac    600

ataagagaat tcatactgga gagaaaccct acaaatgtga agaatgtggc agagctttta    660

gccagtcctc aacccttact gcacataaga taattcatgc tggagagaaa ccttacaaat    720

gtgaagaatg tggcaaagct tttagccagt cctcaaccct tactacacat aagataattc    780

atactggaga gaaattctac aaatgtgaag aatgtggtaa ggcctttagc cagttatccc    840

accttactac acataagaga attcattctg gagagaaacc ctacaagtgt gaagaatgtg    900

gcaaagcttt taaacaatcc tcaaccctta ctacacataa gagaattcat gctggagaga    960

aattctacaa atgtgaagta tgtagcaaag cctttagccg gttctcacac cttactacac   1020

ataagagaat tcatactgga gagaagccct acaaatgtga agaatgtggc aaagctttta   1080

acctatcgtc acaacttact acacataaga taattcatac tggagagaaa ccctacaaat   1140

gtgaagaatg tggcaaagct tttaaccagt cctcaactct ttctaaacat aaggtaattc   1200

atactggaga gaagccctac aaatatgaag aatgtggcaa agcttttaac cagtcctcac   1260

accttactac acataagatg attcatactg gagagaaacc ctacaagtgt gaagaatgtg   1320

gcaaagcctt taacaactcc tctattctta acagacataa gatgattcat actggagaga   1380

aactctacaa acctgaaagt tgtaacaatg cttgtgacaa cattgcaaag atttccaaat   1440

ataaaagaaa ttgtgctggt gagaaataat agaaatatga atgtgacaaa gcctttaaat   1500

ggttatcaca ctggattgta ggtaaggtaa ttcattctgg agaaaacttc tacaagtgtg   1560

aatgaacagt gtggcaaaac ttacacaatg tgctcaaact ttgttcaaca tcagagaatt   1620

tatatcgaag aaaaaccctg taaatgtaat aaatttagaa aaaaacatag caaaatatta   1680

caatgtgata aatatgtgaa agtctttcat aaattttcaa attcaaacag atataagata   1740

agacatactg gaaagaaacc tttcaaatgt aaagaatgtg aaaagtcatt ttgcatgctt   1800

tcacacttag ctcaacataa aagaattcat actagagaga aaccctacaa atgtaaagaa   1860

tgtgggaaag cctataatga ggcctcaaac ctttctacac ataagagaat tcatactgga   1920

aagaaaccct acaaatgcga acagtgtgga aaagccttta accggctctc acaccttact   1980

acacataaga taattcatac tggaaagaaa ccctacatat gtgaggactg tggcaaagct   2040

tttaaccaat ctgcaaacct tactacacat aagagaattc atactggaga gaaaccctac   2100

aaatgtgaag aaagtggcaa agcttttagc cagtcctcaa cccttactac acataagata   2160

attcatgctg gagagaaacc ctacaaatat gaagaatgtg gcaaatcttt taaccaatcc   2220

tcaaccctta ctacacgtaa gataattcat actggagaga aattctgcaa atgtgaagaa   2280

tggggcaagg cctttagccg gttatcccac cttactacac ataagagaat tcattctgga   2340

gagaaaccct acaaatgtga agaatgtggc aaagctttta aacaatcctc aacccttact   2400

acacataaga ggattcattc tggagagaaa ttctacaaat gtgaagtatg tagcaaagcc   2460

tttagccggt tctcacacct tactacacat aagagaattc attctggaga gaagccctac   2520

aaatgtgaag aatgtggcaa agcttttaac ctatcttcac accttactac acataagata   2580

attcatactg gagagaaacc ctacaaatgt gaagaatgtg gcaaagcttt taacctatct   2640

tcacacctta ctacacataa gataattcat actggagaga aaccctacaa atgtgaagaa   2700

tgtggcaaag cttttaacca gtcctcaact ctttctaaac ataaggtaat tcatactgga   2760

gagaaaccct acaaatgtgg agaatgtggc aaagccttta accagtcctc acaccttact   2820

acacataaga taattcatac tggagagaaa ccctacaagt gtgaagaatg tggcaaagcc   2880

tttaacaact cctctattct taacagacat aagatgattc atactggaga gaaattctac   2940

aaacctgaaa gttgtgacaa tgcttgtgac aacatctcaa acatttccaa acataaaaga   3000

aattgtgctg gtgagaaaac atagaaatat gaataatgtg acaaagcctt taaatggtta   3060

tcacacttgt ttgtaagtag ggtaattcat actggagaaa acatcacgag tcctttaaag   3120

tgctgaagag gatttatttt gaagacaaac attacaaata taaagagagt tatagt       3176


<210>  9235
<211>  478
<212>  PRT
<213>  Homo sapiens

<400>  9235

Met Cys Ser Asn Phe Val Gln His Gln Arg Ile Tyr Ile Glu Glu Lys 
1               5                   10                  15


Pro Cys Lys Cys Asn Lys Phe Arg Lys Lys His Ser Lys Ile Leu Gln 
            20                  25                  30


Cys Asp Lys Tyr Val Lys Val Phe His Lys Phe Ser Asn Ser Asn Arg 
        35                  40                  45


Tyr Lys Ile Arg His Thr Gly Lys Lys Pro Phe Lys Cys Lys Glu Cys 
    50                  55                  60


Glu Lys Ser Phe Cys Met Leu Ser His Leu Ala Gln His Lys Arg Ile 
65                  70                  75                  80


His Thr Arg Glu Lys Pro Tyr Lys Cys Lys Glu Cys Gly Lys Ala Tyr 
                85                  90                  95


Asn Glu Ala Ser Asn Leu Ser Thr His Lys Arg Ile His Thr Gly Lys 
            100                 105                 110


Lys Pro Tyr Lys Cys Glu Gln Cys Gly Lys Ala Phe Asn Arg Leu Ser 
        115                 120                 125


His Leu Thr Thr His Lys Ile Ile His Thr Gly Lys Lys Pro Tyr Ile 
    130                 135                 140


Cys Glu Asp Cys Gly Lys Ala Phe Asn Gln Ser Ala Asn Leu Thr Thr 
145                 150                 155                 160


His Lys Arg Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Ser 
                165                 170                 175


Gly Lys Ala Phe Ser Gln Ser Ser Thr Leu Thr Thr His Lys Ile Ile 
            180                 185                 190


His Ala Gly Glu Lys Pro Tyr Lys Tyr Glu Glu Cys Gly Lys Ser Phe 
        195                 200                 205


Asn Gln Ser Ser Thr Leu Thr Thr Arg Lys Ile Ile His Thr Gly Glu 
    210                 215                 220


Lys Phe Cys Lys Cys Glu Glu Trp Gly Lys Ala Phe Ser Arg Leu Ser 
225                 230                 235                 240


His Leu Thr Thr His Lys Arg Ile His Ser Gly Glu Lys Pro Tyr Lys 
                245                 250                 255


Cys Glu Glu Cys Gly Lys Ala Phe Lys Gln Ser Ser Thr Leu Thr Thr 
            260                 265                 270


His Lys Arg Ile His Ser Gly Glu Lys Phe Tyr Lys Cys Glu Val Cys 
        275                 280                 285


Ser Lys Ala Phe Ser Arg Phe Ser His Leu Thr Thr His Lys Arg Ile 
    290                 295                 300


His Ser Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe 
305                 310                 315                 320


Asn Leu Ser Ser His Leu Thr Thr His Lys Ile Ile His Thr Gly Glu 
                325                 330                 335


Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe Asn Leu Ser Ser 
            340                 345                 350


His Leu Thr Thr His Lys Ile Ile His Thr Gly Glu Lys Pro Tyr Lys 
        355                 360                 365


Cys Glu Glu Cys Gly Lys Ala Phe Asn Gln Ser Ser Thr Leu Ser Lys 
    370                 375                 380


His Lys Val Ile His Thr Gly Glu Lys Pro Tyr Lys Cys Gly Glu Cys 
385                 390                 395                 400


Gly Lys Ala Phe Asn Gln Ser Ser His Leu Thr Thr His Lys Ile Ile 
                405                 410                 415


His Thr Gly Glu Lys Pro Tyr Lys Cys Glu Glu Cys Gly Lys Ala Phe 
            420                 425                 430


Asn Asn Ser Ser Ile Leu Asn Arg His Lys Met Ile His Thr Gly Glu 
        435                 440                 445


Lys Phe Tyr Lys Pro Glu Ser Cys Asp Asn Ala Cys Asp Asn Ile Ser 
    450                 455                 460


Asn Ile Ser Lys His Lys Arg Asn Cys Ala Gly Glu Lys Thr 
465                 470                 475


<210>  9236
<211>  618
<212>  DNA
<213>  Homo sapiens

<400>  9236
tgtgacatgt taccatgttc aacagctaaa tgatgtgact cttttctcct gagtgagccc     60

tactcataag ccttgaaccc agatgattta actctcctat ctgggcttcg cctatggaga    120

acactgtgac atacctctgc acccatcatc taggtgatgt gactctcctc tcctgcctgg    180

ttctggctca cagaagggaa tgtaacatgt ctctggatcc agcacctagg tgggattgtg    240

acatacctag gcctagctca caggtgtgat gatgactgtc atatgtggac ccaaccaaca    300

gaaaagattt tgactctcat ggctagaatt aggggaatag attcagggaa tacacctgca    360

gattggtagc ataggtatac tgcatggtgt tgaagtttgg acacttttaa ctatcccatt    420

gcccaagcag tgtacactac acatgggttt ttcttcgata taaattctct gatgttgaac    480

aaagtttgag caattgcctc agggtttgct ctaatacaga atgaatacaa caagatctgt    540

gttacaagta aagttaccac aacttcgttt atatttgtaa tgtttgtctt caaaataaat    600

cctcttcagc actttaaa                                                  618


<210>  9237
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  9237

Met Glu Asn Thr Val Thr Tyr Leu Cys Thr His His Leu Gly Asp Val 
1               5                   10                  15


Thr Leu Leu Ser Cys Leu Val Leu Ala His Arg Arg Glu Cys Asn Met 
            20                  25                  30


Ser Leu Asp Pro Ala Pro Arg Trp Asp Cys Asp Ile Pro Arg Pro Ser 
        35                  40                  45


Ser Gln Val 
    50


<210>  9238
<211>  201
<212>  DNA
<213>  Homo sapiens

<400>  9238
cttttatgaa aatgcagtac atgttaaaaa ttttagatta tgtgtgaact taatttctta     60

attcaacatt tttaacagtt taaatattgt gcattcaatc aagtcacatt attccactta    120

ctttaaccta gtccacctta ctcaagggtg taggtaaaag gtggtaacaa ctatttggta    180

aaagaatgca ctaacatctg t                                              201


<210>  9239
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9239

Phe Asn Ile Phe Asn Ser Leu Asn Ile Val His Ser Ile Lys Ser His 
1               5                   10                  15


Tyr Ser Thr Tyr Phe Asn Leu Val His Leu Thr Gln Gly Cys Arg 
            20                  25                  30


<210>  9240
<211>  572
<212>  DNA
<213>  Homo sapiens

<400>  9240
tgcataggac ctgcactgta cccctcatgt aaagtgtgct ctctaacttt agtctttatt     60

gtaaacttta caaccaccac atactcacat acaaagaata aaaaaaaatt tctttttttc    120

ttgaaagtca gtgatttaca ttttactcta ttaaatctgt tccacattcc tgtaataagg    180

ctgttgaaat gaaccctctt tccccagaag gtcacctgtg tgaatgtgaa taaactgaca    240

ctggcgagga ccagctcagc acactcactt gaactttcgc tctgcttttc agggaatgaa    300

aatgcccttg aagagtaaaa ataaagtgac tgctgattaa gcagagtttc acatgaaaaa    360

agttgtgaaa gccgaggctg gactgtgctg ccgccatctc cgctcactgc aacctccctg    420

cctgatttct cctgcctcag cctgcagact gcctgggatt gcaggcgcgc gccgccacgc    480

ctgactggtt tttgcatttt ttggtggaga ctgggttttg ccgtgttggc cgggctggtc    540

tccagctcct gaccgcgagt gatccgcctg cc                                  572


<210>  9241
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9241

Met Lys Lys Val Val Lys Ala Glu Ala Gly Leu Cys Cys Arg His Leu 
1               5                   10                  15


Arg Ser Leu Gln Pro Pro Cys Leu Ile Ser Pro Ala Ser Ala Cys Arg 
            20                  25                  30


Leu Pro Gly Ile Ala Gly Ala Arg Arg His Ala 
        35                  40


<210>  9242
<211>  1821
<212>  DNA
<213>  Homo sapiens

<400>  9242
aatcatttat taagcattgc cctggcctaa gacaccacat gggtcatttc ttccaggctc     60

caacttgctt ctgctttgcc atatggtaac acgccgtatt atggaagcac catcattacc    120

gccatttgca ggggaagcct aaagagataa atgccagcca gcatccctgt ctctggggcc    180

ctggagaggc cttcaacaca cctggcctca ctgccctgtg gcttcaacaa agaggccgag    240

catctcctat aaaccttgag gtccatggat gacatagcgg aatgatggat ttcagaaaag    300

gcaggtgctt cccactcttt aaatttttgt ttattctttc caagtttccc atcaacagcc    360

ctgcagtaaa aattcagggc ttcagagaca aatatttcat gagtacagac tgtgatgagg    420

aaaagcaagc cattccctct ctatcaggat ccagagcaca ctgctgttac gactccagaa    480

ccgataagga agctatgtgt ggaagtatga gctcaggtcg ccttctgacc ctctgtgacg    540

gtctatttca ggcagttatg gatagataac attacagaca ctgggatctt taacaagtga    600

cacaaacaag agaagaagca ataagaaaat ggctgagaag tggcagagtc aaagttccga    660

tgcaggccca tgggccctct tggttcacct cctccagccc aggcttctaa aactacttcc    720

catacctgct gtattgcagc aaccatgcta atttagcaac ttcccatccc agatgcataa    780

agaagatgga accaattcac catgaatcta tccacccagg catttagaca caaaggtgaa    840

aataacaaca ggccctgtcc tcgagaaact cctcgtccaa caggggaagg gggagagtgc    900

cagtaaacag ggccgttgag ctctgtccca gcagtgggga caggcttgca tagaaccacc    960

ctcactcctg cagcaacttc cctcatgcca gacaagaata gagtgaaagg agacccccac   1020

cttagctttc ttggcctggg gctccatcct gctgtgccta gcaagaacac aacacacaga   1080

cacacaccaa tagatacatg tatcttacca ctactggggg agaaagaaaa gaaaaaataa   1140

atcactggga accgcagcag ggtgagaacc cagacctcag caagtcccaa tttcagaggt   1200

gacagcatct ttaaatgccg caggagtgcg ctcctagctg aggcaggtgt gtggattcaa   1260

cagttgaccc cagctgtcgc agagcgcgag gaagctgcgc agtaaacccc ttacatatca   1320

acctctgagg accggttttt ctgcacctgg tggtccttct agacgtctag gaggatcgtg   1380

ttctcaggag agggttcttc agcatctgtg ctgaagaaca ctgccccagc gggtcacatg   1440

caagattcca ccttcgagca acatagctga cactctgcag cccagttgtc acttgtaaca   1500

aaccccagtg ggtcacatag tgaggggagg caaggctgcg taaggcagtg gctgaactat   1560

cccagaaaac aaggatcaca ggcccccagt gacaccaatg ttgcagaaac acctgcagtg   1620

gcaagtcaga tgtcctccag gaccaggcag ataacaagga gtaggggtct gcagaggcct   1680

cgggagggtc tgcaccatcc aaagaaatca attgttctgc acagtggtaa ggatccagtg   1740

ttcccagcac ttccaaacat ttgaatgaag ccagaattcc agataattat gtgaaatccc   1800

caattactaa atattggcaa c                                             1821


<210>  9243
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  9243

Met Met Asp Phe Arg Lys Gly Arg Cys Phe Pro Leu Phe Lys Phe Leu 
1               5                   10                  15


Phe Ile Leu Ser Lys Phe Pro Ile Asn Ser Pro Ala Val Lys Ile Gln 
            20                  25                  30


Gly Phe Arg Asp Lys Tyr Phe Met Ser Thr Asp Cys Asp Glu Glu Lys 
        35                  40                  45


Gln Ala Ile Pro Ser Leu Ser Gly Ser Arg Ala His Cys Cys Tyr Asp 
    50                  55                  60


Ser Arg Thr Asp Lys Glu Ala Met Cys Gly Ser Met Ser Ser Gly Arg 
65                  70                  75                  80


Leu Leu Thr Leu Cys Asp Gly Leu Phe Gln Ala Val Met Asp Arg 
                85                  90                  95


<210>  9244
<211>  618
<212>  DNA
<213>  Homo sapiens

<400>  9244
gccatttgca ggggaagcct aaagaggctg ataaaatgac tagctacaca ggacccagag     60

ggatgtgccg ctccacctgg ttcccgccgc atcttccccc gaggagccac tagtcccttc    120

ctcctggaac agataaatgc cagccagcat ccctgtctct ggggccctgg agaggccttc    180

aacacacctg gcctcactgc cctgtggctt caacaaagag gccgagcatc tcctataaac    240

cttgaggtcc atggatgaca tagcggaatg atggatttca gaaaagacac aatgaacaaa    300

aaccagagct tttgaataca gatttccagt aaaaccaaac ccagcttggg tcagatgcac    360

ctttccagca accaccatct cagcaacaac ctgccagctg tcaactggaa gttcagcttc    420

tgggaacttc agcccccttc tcagaggagc aaggtcctag caccaacagc acctgcagtg    480

gagcccaagt atggctgctt catggagaag gcaggtatct gtttgcgtgc aaatccgtga    540

gtgcttgcat ctcgtgtatt tgaaaatcct gtttaagaat gcagaggtcc atatagtgtc    600

attaaaacaa atgagtat                                                  618


<210>  9245
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  9245

Met His Leu Ser Ser Asn His His Leu Ser Asn Asn Leu Pro Ala Val 
1               5                   10                  15


Asn Trp Lys Phe Ser Phe Trp Glu Leu Gln Pro Pro Ser Gln Arg Ser 
            20                  25                  30


Lys Val Leu Ala Pro Thr Ala Pro Ala Val Glu Pro Lys Tyr Gly Cys 
        35                  40                  45


Phe Met Glu Lys Ala Gly Ile Cys Leu Arg Ala Asn Pro 
    50                  55                  60


<210>  9246
<211>  435
<212>  DNA
<213>  Homo sapiens

<400>  9246
cagtcttcat ttctcagcgg aaaagccact cccttgagac tctccaggca ccccccaacc     60

gcatttttta tcaagtgtct aaaagacaca atgaacaaaa accagagctt ttgaatacag    120

atttccagta aaaccaaacc cagcttgggt cagatgcacc tttccagcaa ccaccatctc    180

agcaacaacc tgccagctgt caactggaag ttcagcttct gggaacttca gcccccttct    240

cagaggagca aggtcctagc accaacagca cctgcagtgg agcccaagta tggctgcttc    300

atggagaagg caggtatctg tttgcgtgca aatccgtgag tgcttgcatc tcgtgtattt    360

gaaaatcctg tttaagaatg cagaggtcca tatagtgtca ttaaaacaaa tgagtataac    420

cctttggtca tctag                                                     435


<210>  9247
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  9247

Met His Leu Ser Ser Asn His His Leu Ser Asn Asn Leu Pro Ala Val 
1               5                   10                  15


Asn Trp Lys Phe Ser Phe Trp Glu Leu Gln Pro Pro Ser Gln Arg Ser 
            20                  25                  30


Lys Val Leu Ala Pro Thr Ala Pro Ala Val Glu Pro Lys Tyr Gly Cys 
        35                  40                  45


Phe Met Glu Lys Ala Gly Ile Cys Leu Arg Ala Asn Pro 
    50                  55                  60


<210>  9248
<211>  482
<212>  DNA
<213>  Homo sapiens

<400>  9248
atccctttgc tctcaaactc cccgatgcaa tgccttctga tttcaacaga aaagcaagag     60

gctccaggca ccccattcag ggactgccac caaagtaccc gcaaatcctt catgaaaggg    120

gagacattga cacattcttt ttttattctc tggcatggag atgaacatac ttggtatcat    180

ccactctcct gcactgctgg ctcagtcacc agccttttca ggcacggggt ctgcaacctc    240

tctcatggtt tgtgccatct cttgagtcag gagccacaga cctcatccag gacttacagc    300

ctgacagatt aaggagtccg ataaatccac acattctgag ttgttatgct gggcaaaagc    360

catgcccatc cacaagccag actcttggcc tccactggaa gctttggaac tttattccca    420

tcaaacactg acctaatcct tgcactgaga ctgctattta cattaaaatt ggtcacataa    480

tg                                                                   482


<210>  9249
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  9249

Met Gln Cys Leu Leu Ile Ser Thr Glu Lys Gln Glu Ala Pro Gly Thr 
1               5                   10                  15


Pro Phe Arg Asp Cys His Gln Ser Thr Arg Lys Ser Phe Met Lys Gly 
            20                  25                  30


Glu Thr Leu Thr His Ser Phe Phe Ile Leu Trp His Gly Asp Glu His 
        35                  40                  45


Thr Trp Tyr His Pro Leu Ser Cys Thr Ala Gly Ser Val Thr Ser Leu 
    50                  55                  60


Phe Arg His Gly Val Cys Asn Leu Ser His Gly Leu Cys His Leu Leu 
65                  70                  75                  80


Ser Gln Glu Pro Gln Thr Ser Ser Arg Thr Tyr Ser Leu Thr Asp 
                85                  90                  95


<210>  9250
<211>  518
<212>  DNA
<213>  Homo sapiens

<400>  9250
tccaactaca aaaatgaaag gagagaccca atcttgctat gctgcccagg ctagtcttga     60

acccctgacc tcaagcaatc ctcctgtctc agcctcccaa gtctctggga ttacagacac    120

ttccaataag aagactgagc caccaggcag atgttataag caatgtgagc ttgtgctgga    180

agaagagaga atccaccagt gtcctgggcc ctccaaggcc tctctgaggg aaagacattt    240

ggacagagat gccaaggaca aggaagaggc agtcacccac ctctgggcaa ggtgcaaaag    300

cccaagattc acgttcatgt gttgcaagca caaaaagaag atcctgtggc tggagtagag    360

tgaggaacag tgagaatggt aggagcagag ggcagagaaa gtggcaaaaa caaggtcgca    420

tgaggccttg taagccatgg tcaagaggtg atattttatt ttaaatgaat ccaaagtaat    480

tgcaagtttt tgagcaagta agcaaaatgc tcctttgc                            518


<210>  9251
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  9251

Met Lys Gly Glu Thr Gln Ser Cys Tyr Ala Ala Gln Ala Ser Leu Glu 
1               5                   10                  15


Pro Leu Thr Ser Ser Asn Pro Pro Val Ser Ala Ser Gln Val Ser Gly 
            20                  25                  30


Ile Thr Asp Thr Ser Asn Lys Lys Thr Glu Pro Pro Gly Arg Cys Tyr 
        35                  40                  45


Lys Gln Cys Glu Leu Val Leu Glu Glu Glu Arg Ile His Gln Cys Pro 
    50                  55                  60


Gly Pro Ser Lys Ala Ser Leu Arg Glu Arg His Leu Asp Arg Asp Ala 
65                  70                  75                  80


Lys Asp Lys Glu Glu Ala Val Thr His Leu Trp Ala Arg Cys Lys Ser 
                85                  90                  95


Pro Arg Phe Thr Phe Met Cys Cys Lys His Lys Lys Lys Ile Leu Trp 
            100                 105                 110


Leu Glu 



<210>  9252
<211>  2685
<212>  DNA
<213>  Homo sapiens

<400>  9252
agcgagcagg cccagtggag aggcatcctg gctggtctgc gggtgagagc tgatgagcag     60

gagaaactcg tgggggctgt cagatttggc cagagacaga tgctccaaca ggcagatact    120

gtgactgtca gtcggaagcc attggcgttt gccagacagt ggaaggagag ggtcagttcg    180

tcgtgctctt ggccgggggc aggcaggcaa cctgtcgtgc ctttaaggac ctttgggtga    240

ttagagacag gcaggcagct tgccgcctgg aaatgatcaa gtggtcagcc tgaccaaatt    300

caggacagct gaagggtctg actgggcact gtgtgactgg tgggttggag gctgtcgtgt    360

ggctgagcag agatggccag ctgatgggtc acacagttgg ggatggtgtc aggaggtcaa    420

cctgaccagc agagacggct ggcaggaagg tcacggaagg ccagccaggc atggtgccac    480

tgggtgcagg caggtggcgg atctgagtgg cctgacacat tggatggtcg cttatttggg    540

cagcgtgatt gtcagaacag tgtggcaggg gctgctgcag ggagccattt ggacatctgc    600

agggccccgc cggaggcctc ggatggccac gtagggtctg cctatcagga gaacccccag    660

atgatcacag tccccagaga cagccagacc cccggggacc cagcctctca cagtcagtcc    720

tcccacccga gtgaccccga tggcggcctc ccagctggcg gcgctggaag gagtggactc    780

cggtcccagg gtgcccgggg ccagccccgg ctttctatat tccgagggcc agcggctggc    840

actggaggct ctgttgagca agggcgcgga ggcgttccag acctgcgtgc agcgcgagga    900

gctgtggccc ttcctcagtg cggatgaggt tcagggcttg gcagcggcag ctgaagactg    960

gacagtggcc aagcaggagc ccagcgggat ggcagaggga gccaccacca ccgatgtgga   1020

cgcgggcagc ctgagctact ggcctgggca gtcggagcag ccggcgcccg tcctgcggct   1080

gggctggcca gtggactctg cgtggaaagg catcacccgg gcgcagctgt acacccagcc   1140

tcctggagag ggtcagccgc ccctcaagga gctggtgcgg ctggagatcc aggctgccca   1200

caagctggtg gccgtggtca tggacgtctt cactgaccca gacctgcttt tggacttggt   1260

ggatgctgcc acgcgccgct gggtacctgt ctacctgctc ctggaccgcc agcagctgcc   1320

tgccttcctg gaactggccc agcagctggg ggtgaacccc tggaacacgg agaacgtgga   1380

tgtccgtgtc gtgcggggct gcagcttcca gagccgctgg cgacggcagg tgagcggcac   1440

cgtgcgggag aagtttgtgc tgctggacgg cgagagggtc atctcaggat cctacagctt   1500

cacgtggagt gacgcacgcc tgcaccgagg cctggtgacc ctgctgactg gtgaaattgt   1560

tgacgccttc agccttgagt tccggacgct gtacgcggcc tcctgcccgc tcccacctgc   1620

gcccccccag aaaccctcgg tcataggtgg cctgcagcgg ggccgcagcc cgcaccgcgt   1680

gtcccgccgc cgctccgtgg cccccgcgtc gcctccgccg cctgacggcc cgctggccca   1740

ccgcctggcc gcctgccgcg tctcccctgc taccccgggg ccggcactca gtgacattct   1800

aaggagtgtg cagcgcgccc ggacccccag cggccccccg gcccggccca gccgctccat   1860

gtgggaccta agccgcctgt cccagctgtc tggctccagt gatggggaca acgagctcaa   1920

gaaatcctgg ggctccaagg acactccagc caaggctctg atgaggcagc ggggcactgg   1980

aggaggcccc tggggggaag tggactcccg acctccgtgg ggcggtgccc tgcccctgcc   2040

ccccgcccac cgcctccgct atctgtcccc agcccgaagg cggttcggtg gggatgctac   2100

attcaaactt caagagccca gaggcgtcag gccgtcagac tgggcccccc gggcaggact   2160

tggggggcaa ccctgaacag gagcccaagc caaatctgct ggcccaccca aggagcagtg   2220

ccggacaact gtcggctcag agccctctgc ctcaatgccc tgccttggac aaggcttctg   2280

gcctcggcgt ctgtcaagca gaagggatgt ttgtcacttg ttctgcaact tgggccggga   2340

gtggtggctc atgcctgtaa tccctgcact ttgggaggct aaggtgggag ggttgcttaa   2400

ggccaggagt tggagaccag cctgggcaac atagtgagac cccatctcta caattaaaaa   2460

aacaaattag ttgggtgtgg tggcgcacgc ctgtggtccc agctacgcag gaggctgagg   2520

tgggaggatc ccttgagctc aggaggtgga ggcagcagtg agccaagatc atgcccttgc   2580

actccagcct gggcaacaca gtgagaggcc atctctttaa aaaaaaaaaa aaaagaaaaa   2640

agaaaaagaa aggctgatcg aggtggctca ctcctgtaat cccag                   2685


<210>  9253
<211>  478
<212>  PRT
<213>  Homo sapiens

<400>  9253

Met Ala Ala Ser Gln Leu Ala Ala Leu Glu Gly Val Asp Ser Gly Pro 
1               5                   10                  15


Arg Val Pro Gly Ala Ser Pro Gly Phe Leu Tyr Ser Glu Gly Gln Arg 
            20                  25                  30


Leu Ala Leu Glu Ala Leu Leu Ser Lys Gly Ala Glu Ala Phe Gln Thr 
        35                  40                  45


Cys Val Gln Arg Glu Glu Leu Trp Pro Phe Leu Ser Ala Asp Glu Val 
    50                  55                  60


Gln Gly Leu Ala Ala Ala Ala Glu Asp Trp Thr Val Ala Lys Gln Glu 
65                  70                  75                  80


Pro Ser Gly Met Ala Glu Gly Ala Thr Thr Thr Asp Val Asp Ala Gly 
                85                  90                  95


Ser Leu Ser Tyr Trp Pro Gly Gln Ser Glu Gln Pro Ala Pro Val Leu 
            100                 105                 110


Arg Leu Gly Trp Pro Val Asp Ser Ala Trp Lys Gly Ile Thr Arg Ala 
        115                 120                 125


Gln Leu Tyr Thr Gln Pro Pro Gly Glu Gly Gln Pro Pro Leu Lys Glu 
    130                 135                 140


Leu Val Arg Leu Glu Ile Gln Ala Ala His Lys Leu Val Ala Val Val 
145                 150                 155                 160


Met Asp Val Phe Thr Asp Pro Asp Leu Leu Leu Asp Leu Val Asp Ala 
                165                 170                 175


Ala Thr Arg Arg Trp Val Pro Val Tyr Leu Leu Leu Asp Arg Gln Gln 
            180                 185                 190


Leu Pro Ala Phe Leu Glu Leu Ala Gln Gln Leu Gly Val Asn Pro Trp 
        195                 200                 205


Asn Thr Glu Asn Val Asp Val Arg Val Val Arg Gly Cys Ser Phe Gln 
    210                 215                 220


Ser Arg Trp Arg Arg Gln Val Ser Gly Thr Val Arg Glu Lys Phe Val 
225                 230                 235                 240


Leu Leu Asp Gly Glu Arg Val Ile Ser Gly Ser Tyr Ser Phe Thr Trp 
                245                 250                 255


Ser Asp Ala Arg Leu His Arg Gly Leu Val Thr Leu Leu Thr Gly Glu 
            260                 265                 270


Ile Val Asp Ala Phe Ser Leu Glu Phe Arg Thr Leu Tyr Ala Ala Ser 
        275                 280                 285


Cys Pro Leu Pro Pro Ala Pro Pro Gln Lys Pro Ser Val Ile Gly Gly 
    290                 295                 300


Leu Gln Arg Gly Arg Ser Pro His Arg Val Ser Arg Arg Arg Ser Val 
305                 310                 315                 320


Ala Pro Ala Ser Pro Pro Pro Pro Asp Gly Pro Leu Ala His Arg Leu 
                325                 330                 335


Ala Ala Cys Arg Val Ser Pro Ala Thr Pro Gly Pro Ala Leu Ser Asp 
            340                 345                 350


Ile Leu Arg Ser Val Gln Arg Ala Arg Thr Pro Ser Gly Pro Pro Ala 
        355                 360                 365


Arg Pro Ser Arg Ser Met Trp Asp Leu Ser Arg Leu Ser Gln Leu Ser 
    370                 375                 380


Gly Ser Ser Asp Gly Asp Asn Glu Leu Lys Lys Ser Trp Gly Ser Lys 
385                 390                 395                 400


Asp Thr Pro Ala Lys Ala Leu Met Arg Gln Arg Gly Thr Gly Gly Gly 
                405                 410                 415


Pro Trp Gly Glu Val Asp Ser Arg Pro Pro Trp Gly Gly Ala Leu Pro 
            420                 425                 430


Leu Pro Pro Ala His Arg Leu Arg Tyr Leu Ser Pro Ala Arg Arg Arg 
        435                 440                 445


Phe Gly Gly Asp Ala Thr Phe Lys Leu Gln Glu Pro Arg Gly Val Arg 
    450                 455                 460


Pro Ser Asp Trp Ala Pro Arg Ala Gly Leu Gly Gly Gln Pro 
465                 470                 475


<210>  9254
<211>  676
<212>  DNA
<213>  Homo sapiens

<400>  9254
gaagccggga agcaccgcag aagtagaagc cggggagcca cagcctacgt tctcggaaaa     60

agcaggcact ggaagggagg ccattgagcc cggcactagc cggtgtggcc ccggctttct    120

atattccgag ggccagcggc tggcactgga ggctctgttg agcaagggcg cggaggcgtt    180

ccagacctgc gtgcagcgcg aggagctgtg gcccttcctc agtgcggatg aggttcaggg    240

cttggcagcg gcagctgaag actggacagt ggccaagcag gagcccagcg ggatggcaga    300

gggagccacc accaccgatg tggacgcggg cagcctgagc tactggcctg ggcagtcgga    360

gcagccggcg cccgtcctgc ggctgggctg gccagtggac tctgcgtgga aaggcatcac    420

ccgggcgcag ctgtacaccc agcctcctgg agagggtcag ccgcccctca aggagctggt    480

gcggctggag atccaggctg cccacaagct ggtggccgtg gtcatggacg tcttcactga    540

cccagacctg cttttggact tggtggatgc tgccacgcgc cgctgggtac ctgtctacct    600

gctcctggac cgccagcagc tgcctgcctt cctggaactg gcccagcagc tgggggtgaa    660

cccctggaac acggag                                                    676


<210>  9255
<211>  127
<212>  PRT
<213>  Homo sapiens

<400>  9255

Met Ala Glu Gly Ala Thr Thr Thr Asp Val Asp Ala Gly Ser Leu Ser 
1               5                   10                  15


Tyr Trp Pro Gly Gln Ser Glu Gln Pro Ala Pro Val Leu Arg Leu Gly 
            20                  25                  30


Trp Pro Val Asp Ser Ala Trp Lys Gly Ile Thr Arg Ala Gln Leu Tyr 
        35                  40                  45


Thr Gln Pro Pro Gly Glu Gly Gln Pro Pro Leu Lys Glu Leu Val Arg 
    50                  55                  60


Leu Glu Ile Gln Ala Ala His Lys Leu Val Ala Val Val Met Asp Val 
65                  70                  75                  80


Phe Thr Asp Pro Asp Leu Leu Leu Asp Leu Val Asp Ala Ala Thr Arg 
                85                  90                  95


Arg Trp Val Pro Val Tyr Leu Leu Leu Asp Arg Gln Gln Leu Pro Ala 
            100                 105                 110


Phe Leu Glu Leu Ala Gln Gln Leu Gly Val Asn Pro Trp Asn Thr 
        115                 120                 125


<210>  9256
<211>  1878
<212>  DNA
<213>  Homo sapiens

<400>  9256
aggtcgaggc ctgatgagtg aggccagaag ccgggaagca ccgcagaagt agaagccggg     60

gagccacagc ctacgttctc ggaaaaagca ggcactggaa gggaggccat tgagcccggc    120

actagccggt gtggctccct gctgtggtct ggaggaagca gcggcctggg ttggtgggat    180

tggaatgaag ggcttctggt ttgcagggat caagggtcca gggtccccga ggttgggtca    240

ggagcctcaa ggggataact gaggcttggg agggagacag ggcgagatag agactggccc    300

ctgtccggga agaagcgtcc gggtagctgg caggagatag catttaggca gaaaccaggc    360

tgggggcagc ttgggtaggg ctccccgcag atcagaggac ggcctggaac aggtcccagg    420

gccaggcccc aggcaggggc agccagcctg aggagggtgg ctggttaggt ggcactcaca    480

cctagatggg ctgtgaagat catagacctg tcccatagta atggagaccc ctgtagcgca    540

tttcaccctc cactgcagca gctggaagga gtgtgaggag ggtccaggga gcagggtccc    600

ccattgacag ggtagggaag ggtttgccaa gccttcggcc tttaaggctg agcgagcagg    660

cccagtggag aggcatcctg gctggtctgc gggtgagagc tgatgagcag gagaaactcg    720

tgggggctgt cagatttggc cagagacaga tgctccaaca ggcagatact gtgactgtca    780

gtcggaagcc attggcgttt gccagacagt ggaaggagag ggtcagttcg tcgtgctctt    840

ggccgggggc aggcaggcaa cctgtcgtgc ctttaaggac ctttgggtga ttagagacag    900

gcaggcagct tgccgcctgg aaatgatcaa gtggtcagcc tgaccaaatt caggacagct    960

gaagggtctg actgggcact gtgtgactgg tgggttggag gctgtcgtgt ggctgagcag   1020

agatggccag ctgatgggtc acacagttgg ggatggtgtc aggaggtcaa cctgaccagc   1080

agagacggct ggcaggaagg tcacggaagg ccagccaggc atggtgccac tgggtgcagg   1140

caggtggcgg atctgagtgg cctgacacat tggatggtcg cttatttggg cagcgtgatt   1200

gtcagaacag tgtggcaggg gctgctgcag ggagccattt ggacatctgc agggccccgc   1260

cggaggcctc ggatggccac gtagggtctg cctatcagga gaacccccag atgatcacag   1320

tccccagaga cagccagacc cccggggacc cagcctctca cagtcagtcc tcccacccga   1380

gtgaccccga tggcggcctc ccagctggcg gcgctggaag gagtggactc cggtcccagg   1440

gtgcccgggg ccagccccgg ctttctatat tccgagggcc agcggctggc actggaggct   1500

ctgttgagca agggcgcgga ggcgttccag acctgcgtgc agcgcgagga gctgtggccc   1560

ttcctcagtg cggatgaggt tcagggcttg gcagcggcag ctgaagactg gacagtggcc   1620

aagcaggagc ccagcgggat ggcagaggga gccaccacca ccgatgtgga cgcgggcagc   1680

ctgagctact ggcctgggca gtcggagcag ccggcgcccg tcctgcggct gggctggcca   1740

gtggactctg cgtggaaagg catcacccgg gcgcagctgt acacccagcc tcctggagag   1800

ggtcagccgc ccctcaagga gctggtgcgg ctggagatcc aggctgccca caaggtgggt   1860

gtcgcggggg ccctgtgt                                                 1878


<210>  9257
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  9257

Met Val Ser Gly Gly Gln Pro Asp Gln Gln Arg Arg Leu Ala Gly Arg 
1               5                   10                  15


Ser Arg Lys Ala Ser Gln Ala Trp Cys His Trp Val Gln Ala Gly Gly 
            20                  25                  30


Gly Ser Glu Trp Pro Asp Thr Leu Asp Gly Arg Leu Phe Gly Gln Arg 
        35                  40                  45


Asp Cys Gln Asn Ser Val Ala Gly Ala Ala Ala Gly Ser His Leu Asp 
    50                  55                  60


Ile Cys Arg Ala Pro Pro Glu Ala Ser Asp Gly His Val Gly Ser Ala 
65                  70                  75                  80


Tyr Gln Glu Asn Pro Gln Met Ile Thr Val Pro Arg Asp Ser Gln Thr 
                85                  90                  95


Pro Gly Asp Pro Ala Ser His Ser Gln Ser Ser His Pro Ser Asp Pro 
            100                 105                 110


Asp Gly Gly Leu Pro Ala Gly Gly Ala Gly Arg Ser Gly Leu Arg Ser 
        115                 120                 125


Gln Gly Ala Arg Gly Gln Pro Arg Leu Ser Ile Phe Arg Gly Pro Ala 
    130                 135                 140


Ala Gly Thr Gly Gly Ser Val Glu Gln Gly Arg Gly Gly Val Pro Asp 
145                 150                 155                 160


Leu Arg Ala Ala Arg Gly Ala Val Ala Leu Pro Gln Cys Gly 
                165                 170


<210>  9258
<211>  1796
<212>  DNA
<213>  Homo sapiens

<400>  9258
agggagagac tgcctgggaa caggtcgagg cctgatgagt gaggccagaa gccgggaagc     60

accgcagaag tagaagccgg ggagccacag cctacgttct cggaaaaagc aggcactgga    120

agggaggcca ttgagcccgg cactagccgg tgtggctccc tgctgtggtc tggaggaagc    180

agcggcctgg gttggtggga ttggaatgaa gggcttctgg tttgcaggga tcaagggtcc    240

agggtccccg aggttgggtc aggagcctca aggggataac tgaggcttgg gagggagaca    300

gggcgagata gagactggcc cctgtccggg aagaagcgtc cgggtagctg gcaggggcag    360

ccagcctgag gagggtggct ggttaggtgg cactcacacc tagatgggct gtgaagatca    420

tagacctgtc ccatagtaat ggagacccct gtagcgcatt tcaccctcca ctgcagcagc    480

tggaaggagt gtgaggaggg tccagggagc agggtccccc attgacaggg tagggaaggg    540

tttgccaagc cttcggcctt taaggctgag cgagcaggcc cagtggagag gcatcctggc    600

tggtctgcgg gtgagagctg atgagcagga gaaactcgtg ggggctgtca gatttggcca    660

gagacagatg ctccaacagg cagatactgt gactgtcagt cggaagccat tggcgtttgc    720

cagacagtgg aaggagaggg tcagttcgtc gtgctcttgg ccgggggcag gcaggcaacc    780

tgtcgtgcct ttaaggacct ttgggtgatt agagacaggc aggcagcttg ccgcctggaa    840

atgatcaagt ggtcagcctg accaaattca ggacagctga agggtctgac tgggcactgt    900

gtgactggtg ggttggaggc tgtcgtgtgg ctgagcagag atggccagct gatgggtcac    960

acagttgggg atggtgtcag gaggtcaacc tgaccagcag agacggctgg caggaaggtc   1020

acggaaggcc agccaggcat ggtgccactg ggtgcaggca ggtggcggat ctgagtggcc   1080

tgacacattg gatggtcgct tatttgggca gcgtgattgt cagaacagtg tggcaggggc   1140

tgctgcaggg agccatttgg acatctgcag ggccccgccg gaggcctcgg atggccacgt   1200

agggtctgcc tatcaggaga acccccagat gatcacagtc cccagagaca gccagacccc   1260

cggggaccca gcctctcaca gtcagtcctc ccacccgagt gaccccgatg gcggcctccc   1320

agctggcggc gctggaagga gtggactccg gtcccagggt gcccggggcc agccccggct   1380

ttctatattc cgagggccag cggctggcac tggaggctct gttgagcaag ggcgcggagg   1440

cgttccagac ctgcgtgcag cgcgaggagc tgtggccctt cctcagtgcg gatgaggttc   1500

agggcttggc agcggcagct gaagactgga cagtggccaa gcaggagccc agcgggatgg   1560

cagagggagc caccaccacc gatgtggacg cgggcagcct gagctactgg cctgggcagt   1620

cggagcagcc ggcgcccgtc ctgcggctgg gctggccagt ggactctgcg tggaaaggca   1680

tcacccgggc gcagctgtac acccagcctc ctggagaggg tcagccgccc ctcaaggagc   1740

tggtgcggct ggagatccag gctgcccaca aggtgggtgt cgcgggggcc ctgtgt       1796


<210>  9259
<211>  174
<212>  PRT
<213>  Homo sapiens

<400>  9259

Met Val Ser Gly Gly Gln Pro Asp Gln Gln Arg Arg Leu Ala Gly Arg 
1               5                   10                  15


Ser Arg Lys Ala Ser Gln Ala Trp Cys His Trp Val Gln Ala Gly Gly 
            20                  25                  30


Gly Ser Glu Trp Pro Asp Thr Leu Asp Gly Arg Leu Phe Gly Gln Arg 
        35                  40                  45


Asp Cys Gln Asn Ser Val Ala Gly Ala Ala Ala Gly Ser His Leu Asp 
    50                  55                  60


Ile Cys Arg Ala Pro Pro Glu Ala Ser Asp Gly His Val Gly Ser Ala 
65                  70                  75                  80


Tyr Gln Glu Asn Pro Gln Met Ile Thr Val Pro Arg Asp Ser Gln Thr 
                85                  90                  95


Pro Gly Asp Pro Ala Ser His Ser Gln Ser Ser His Pro Ser Asp Pro 
            100                 105                 110


Asp Gly Gly Leu Pro Ala Gly Gly Ala Gly Arg Ser Gly Leu Arg Ser 
        115                 120                 125


Gln Gly Ala Arg Gly Gln Pro Arg Leu Ser Ile Phe Arg Gly Pro Ala 
    130                 135                 140


Ala Gly Thr Gly Gly Ser Val Glu Gln Gly Arg Gly Gly Val Pro Asp 
145                 150                 155                 160


Leu Arg Ala Ala Arg Gly Ala Val Ala Leu Pro Gln Cys Gly 
                165                 170


<210>  9260
<211>  1005
<212>  DNA
<213>  Homo sapiens

<400>  9260
actgggcccg ccgggtcctc cgggagccac tgagaggccg tcggcgtcgg gccagagcgt     60

caccgcgcga cgcatcgtgc tagctacacg catctcgctc ccagatccct ttcttccgga    120

aagctatcga gaacacggcc tgggtagggc cagagaggcc cccgacgtgc tggcccttcc    180

ctcttggacg ttgcgcttgt tcctgcgctc tatgctctct gccgttatcg cccggctagt    240

cagtcgtcca actcaccaca gagaagtccg gatcgtggta gagcgccgcg tcgcacccat    300

gtgacgtcac ggcggcgcca ctcgcttgag gctttccccg cccaccccag cccgttctct    360

ctttccggac ctggccgagc aggaggcgcc atcatgggag tggacatccg ccataacaag    420

gaccgaaagg ttcggcgcaa ggagcccaag agccaggata tctacctgag gctgttggtc    480

aagttataca ggtttctggc cagaagaacc aactccacat tcaaccaggt tgtgttgaag    540

aggttgttta tgagtcgcac caaccggccg cctctgtccc tttcccggat gatccggaag    600

atgaagcttc ctggccggga aaacaagacg gccgtggttg tggggaccat aactgatgat    660

gtgcgggttc aggaggtacc caaactgaag gtatgtgcac tgcgcgtgac cagccgggcc    720

cgcagccgca tcctcagggc agggggcaag atcctcactt tcgaccagct ggccctggac    780

tcccctaagg gctgtggcac tgtcctgctc tccggtcctc gcaagggccg agaggtgtac    840

cggcatttcg gcaaggcccc aggaaccccg cacagccaca ccaaacccta cgtccgctcc    900

aagggccgga agttcgagcg tgccagaggc cgacgggcca gccgaggcta caaaaactaa    960

ccctggatcc tactctctta ttaaaaagat ttttgctgac agtgc                   1005


<210>  9261
<211>  188
<212>  PRT
<213>  Homo sapiens

<400>  9261

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu Ser Leu Ser 
    50                  55                  60


Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn Lys Thr Ala 
65                  70                  75                  80


Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln Glu Val Pro 
                85                  90                  95


Lys Leu Lys Val Cys Ala Leu Arg Val Thr Ser Arg Ala Arg Ser Arg 
            100                 105                 110


Ile Leu Arg Ala Gly Gly Lys Ile Leu Thr Phe Asp Gln Leu Ala Leu 
        115                 120                 125


Asp Ser Pro Lys Gly Cys Gly Thr Val Leu Leu Ser Gly Pro Arg Lys 
    130                 135                 140


Gly Arg Glu Val Tyr Arg His Phe Gly Lys Ala Pro Gly Thr Pro His 
145                 150                 155                 160


Ser His Thr Lys Pro Tyr Val Arg Ser Lys Gly Arg Lys Phe Glu Arg 
                165                 170                 175


Ala Arg Gly Arg Arg Ala Ser Arg Gly Tyr Lys Asn 
            180                 185


<210>  9262
<211>  1331
<212>  DNA
<213>  Homo sapiens

<400>  9262
agacggccgt ggttgtgggg accataactg atgatgtgcg ggttcaggag gtacccaaac     60

tgaaggtgag ctggcggggg ctgggcagac ccatcagacc cttgctgtac tgtgctgtgc    120

tgtgctgtgc tgtgctgtgc tgtgctggtc catcctcagt cttgccaccg ctggtgaggc    180

aagcatcctg cctgtctgag tggctttgag gattggtgtg ggtcgtctct ggcatggttg    240

atggtggggt cccctgggca agcttcttct ggggcaagtt gtaaactgtt agtgctggcc    300

cctagagcca gacagcctgg gctcaagtct agactccttt gtcacctctg cacaggtctt    360

tttttggccc agcttccttg ctgtagtttc tagcataaca ccagggatgt ggtggtgaaa    420

gttccggaag tgttgagaac tgctgctgtc agcccagggt gctccgggta gtaaacgata    480

gtgttggtta ccagggctct gctgcgccaa ggcagtggag ggtgagtcct ggcagcccct    540

gggtgaccac gcaggggtct gacccgccag ccttgtcctc tccaccaggt atgtgcactg    600

cgcgtgacca gccgggcccg cagccgcatc ctcagggcag ggggcaagat cctcactttc    660

gaccagctgg ccctggactc ccctaagggc tgtggcactg tcctgctctc cggtcctcgc    720

aagggccgag aggtgtaccg gcatttcggc aaggccccag gaaccccgca cagccacacc    780

aagtgagtat caggccccca gccctgccct ctccccagac tcagcctgca gggccaggcc    840

tggccacact tgggctgctt ctcctatccc tcgtaccagc cagccccagg ccttctggaa    900

ctctcagctg cctcatcctg cctgcttttc ccttcaacac tgcttggagc tgtgttttcc    960

agggcctgag caggcatctc ctggggagca tgcagttcac cggcctttgc cagcccaggc   1020

tgggaccctc caggtggtgg ggcaggtgct tccatagccc ctcctggctc cttggcttcc   1080

cactctgcca agcttttcca gcagcattga ctctcctggg gctgaatgtg acaggcttgt   1140

ggtgttcctg tgccactcca caatggcctc ctttaagagg gcccccctct cactccctcc   1200

tctccccaca gaccctacgt ccgctccaag ggccggaagt tcgagcgtgc cagaggccga   1260

cgggccagcc gaggctacaa aaactaaccc tggatcctac tctcttatta aaaagatttt   1320

tgctgacagt g                                                        1331


<210>  9263
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  9263

Met Gln Phe Thr Gly Leu Cys Gln Pro Arg Leu Gly Pro Ser Arg Trp 
1               5                   10                  15


Trp Gly Arg Cys Phe His Ser Pro Ser Trp Leu Leu Gly Phe Pro Leu 
            20                  25                  30


Cys Gln Ala Phe Pro Ala Ala Leu Thr Leu Leu Gly Leu Asn Val Thr 
        35                  40                  45


Gly Leu Trp Cys Ser Cys Ala Thr Pro Gln Trp Pro Pro Leu Arg Gly 
    50                  55                  60


Pro Pro Ser His Ser Leu Leu Ser Pro Gln Thr Leu Arg Pro Leu Gln 
65                  70                  75                  80


Gly Pro Glu Val Arg Ala Cys Gln Arg Pro Thr Gly Gln Pro Arg Leu 
                85                  90                  95


Gln Lys Leu Thr Leu Asp Pro Thr Leu Leu Leu Lys Arg Phe Leu Leu 
            100                 105                 110


Thr 



<210>  9264
<211>  1629
<212>  DNA
<213>  Homo sapiens

<400>  9264
ggccgagcag gaggcgccat catgttatac aggtttctgg ccagaagaac caactccaca     60

ttcaaccagg ttgtgttgaa gaggttgttt atgagtcgca ccaaccggcc gcctctgtcc    120

ctttcccgga tgatccggaa gatgaagctt cctggccggg aaaacaagac ggccgtggtt    180

gtggggacca taactgatga tgtgcgggtt caggaggtac ccaaactgaa ggtgagctgg    240

cgggggctgg gcagacccat cagacccttg ctgtactgtg ctgtgctgtg ctgtgctgtg    300

ctgtgctgtg ctggtccatc ctcagtcttg ccaccgctgg tgaggcaagc atcctgcctg    360

tctgagtggc tttgaggatt ggtgtgggtc gtctctggca tggttgatgg tggggtcccc    420

tgggcaagct tcttctgggg caagttgtaa actgttagtg ctggccccta gagccagaca    480

gcctgggctc aagtctagac tcctttgtca cctctgcaca ggtctttttt tggcccagct    540

tccttgctgt agtttctagc ataacaccag ggatgtggtg gtgaaagttc cggaagtgtt    600

gagaactgct gctgtcagcc cagggtgctc cgggtagtaa acgatagtgt tggttaccag    660

ggctctgctg cgccaaggca gtggagggtg agtcctggca gcccctgggt gaccacgcag    720

gggtctgacc cgccagcctt gtcctctcca ccaggtatgt gcactgcgcg tgaccagccg    780

ggcccgcagc cgcatcctca gggcaggggg caagatcctc actttcgacc agctggccct    840

ggactcccct aagggctgtg gcactgtcct gctctccggt gagtgatacg tggtcgacgg    900

gtttggactg agctgtgtgg ctactggcag ccttcaccct cctggatctg ggaggccaga    960

agctgggcgc cagatccctg tctcacccgg ttctccttcc ccttccctag gtcctcgcaa   1020

gggccgagag gtgtaccggc atttcggcaa ggccccagga accccgcaca gccacaccaa   1080

gtgagtatca ggcccccagc cctgccctct ccccagactc agcctgcagg gccaggcctg   1140

gccacacttg ggctgcttct cctatccctc gtaccagcca gccccaggcc ttctggaact   1200

ctcagctgcc tcatcctgcc tgcttttccc ttcaacactg cttggagctg tgttttccag   1260

ggcctgagca ggcatctcct ggggagcatg cagttcaccg gcctttgcca gcccaggctg   1320

ggaccctcca ggtggtgggg caggtgcttc catagcccct cctggctcct tggcttccca   1380

ctctgccaag cttttccagc agcattgact ctcctggggc tgaatgtgac aggcttgtgg   1440

tgttcctgtg ccactccaca atggcctcct ttaagagggc ccccctctca ctccctcctc   1500

tccccacaga ccctacgtcc gctccaaggg ccggaagttc gagcgtgcca gaggccgacg   1560

ggccagccga ggctacaaaa actaaccctg gatcctactc tcttattaaa aagatttttg   1620

ctgacagtg                                                           1629


<210>  9265
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  9265

Met Leu Tyr Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln 
1               5                   10                  15


Val Val Leu Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu 
            20                  25                  30


Ser Leu Ser Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn 
        35                  40                  45


Lys Thr Ala Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln 
    50                  55                  60


Glu Val Pro Lys Leu Lys Val Ser Trp Arg Gly Leu Gly Arg Pro Ile 
65                  70                  75                  80


Arg Pro Leu Leu Tyr Cys Ala Val Leu Cys Cys Ala Val Leu Cys Cys 
                85                  90                  95


Ala Gly Pro Ser Ser Val Leu Pro Pro Leu Val Arg Gln Ala Ser Cys 
            100                 105                 110


Leu Ser Glu Trp Leu 
        115


<210>  9266
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  9266
tccggacctg gccgagcagg aggcgccatc atgggagtgg acatccgcca taacaaggac     60

cgaaaggttc ggcgcaagga gcccaagagc caggatatct acctgaggct gttggtcaag    120

ttatacaggt ttctggccag aagaaccaac tccacattca accaggttgt gttgaagagg    180

ttgtggggac cataactgat gatgtgcggg ttcaggaggt acccaaactg aaggtatgtg    240

cactgcgcgt gaccagccgg gcccgcagcc gcatcctcag ggcagggggc aagatcctca    300

ctttcgacca gctggccctg gactccccta agggctgtgg cactgtcctg ctctccggtc    360

ctcgcaaggg ccgagaggtg taccggcatt tcggcaaggc cccaggaacc ccgcacagcc    420

acaccaaacc ctacgtccgc tccaagggcc ggaagttcga gcgtgccaga ggccgacggg    480

ccagccgagg ctacaaaaac taaccctgga tcctactctc ttattaaaaa gatttttgct    540

gacagtg                                                              547


<210>  9267
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  9267

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Trp Gly Pro 
    50


<210>  9268
<211>  472
<212>  DNA
<213>  Homo sapiens

<400>  9268
ctttccggac ctggccgagc aggaggcgcc atcatgggag tggacatccg ccataacaag     60

gaccgaaagg ttcggcgcaa ggagcccaag agccaggata tctacctgag gctgttggtc    120

aagttataca ggtttctggc cagaagaacc aactccacat tcaaccaggt tgtgttgaag    180

aggttgttta tgaccgcatc ctcagggcag ggggcaagat cctcactttc gaccagctgg    240

ccctggactc ccctaagggc tgtggcactg tcctgctctc cggtcctcgc aagggccgag    300

aggtgtaccg gcatttcggc aaggccccag gaaccccgca cagccacacc aaaccctacg    360

tccgctccaa gggccggaag ttcgagcgtg ccagaggccg acgggccagc cgaggctaca    420

aaaactaacc ctggatccta ctctcttatt aaaaagattt ttgctgacag tg            472


<210>  9269
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  9269

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Phe Met Thr Ala Ser Ser Gly Gln Gly Ala Arg Ser Ser 
    50                  55                  60


Leu Ser Thr Ser Trp Pro Trp Thr Pro Leu Arg Ala Val Ala Leu Ser 
65                  70                  75                  80


Cys Ser Pro Val Leu Ala Arg Ala Glu Arg Cys Thr Gly Ile Ser Ala 
                85                  90                  95


Arg Pro Gln Glu Pro Arg Thr Ala Thr Pro Asn Pro Thr Ser Ala Pro 
            100                 105                 110


Arg Ala Gly Ser Ser Ser Val Pro Glu Ala Asp Gly Pro Ala Glu Ala 
        115                 120                 125


Thr Lys Thr Asn Pro Gly Ser Tyr Ser Leu Ile Lys Lys Ile Phe Ala 
    130                 135                 140


Asp 
145


<210>  9270
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  9270
tctctctttc cggacctggc cgagcaggag gcgccatcat gttatacagg tttctggcca     60

gaagaaccaa ctccacattc aaccaggttg tgttgaagag gttgtttatg agtcgcacca    120

accggccgcc tctgtccctt tcccggatga tccggaagat gaagcttcct ggccgggaaa    180

acaagacggc cgtggttgtg gggaccataa ctgatgatgt gcgggttcag gaggtaccca    240

aactgaaggt atgtgcactg cgcgtgacca gccgggcccg cagccgcatc ctcagggcag    300

ggggcaagat cctcactttc gaccagctgg ccctggactc ccctaagggc tgtggcactg    360

tcctgctctc cggtcctcgc aagggccgag aggtgtaccg gcatttcggc aaggccccag    420

gaaccccgca cagccacacc aaaccctacg tccgctccaa gggccggaag ttcgagcgtg    480

ccagaggccg acgggccagc cgaggctaca aaaactaacc ctggatccta ctctcttatt    540

aaaaagattt ttgctgacag tg                                             562


<210>  9271
<211>  159
<212>  PRT
<213>  Homo sapiens

<400>  9271

Met Leu Tyr Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln 
1               5                   10                  15


Val Val Leu Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu 
            20                  25                  30


Ser Leu Ser Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn 
        35                  40                  45


Lys Thr Ala Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln 
    50                  55                  60


Glu Val Pro Lys Leu Lys Val Cys Ala Leu Arg Val Thr Ser Arg Ala 
65                  70                  75                  80


Arg Ser Arg Ile Leu Arg Ala Gly Gly Lys Ile Leu Thr Phe Asp Gln 
                85                  90                  95


Leu Ala Leu Asp Ser Pro Lys Gly Cys Gly Thr Val Leu Leu Ser Gly 
            100                 105                 110


Pro Arg Lys Gly Arg Glu Val Tyr Arg His Phe Gly Lys Ala Pro Gly 
        115                 120                 125


Thr Pro His Ser His Thr Lys Pro Tyr Val Arg Ser Lys Gly Arg Lys 
    130                 135                 140


Phe Glu Arg Ala Arg Gly Arg Arg Ala Ser Arg Gly Tyr Lys Asn 
145                 150                 155


<210>  9272
<211>  1737
<212>  DNA
<213>  Homo sapiens

<400>  9272
ccgttctctc tttccggacc tggccgagca ggaggcgcca tcatgggagt ggacatccgc     60

cataacaagg accgaaaggt tcggcgcaag gagcccaaga gccaggatat ctacctgagg    120

ctgttggtca agttatacag gtttctggcc agaagaacca actccacatt caaccaggtt    180

gtgttgaaga ggttgtttat gagtcgcacc aaccggccgc ctctgtccct ttcccggatg    240

atccggaaga tgaagcttcc tggccgggaa aacaagacgg ccgtggttgt ggggaccata    300

actgatgatg tgcgggttca ggaggtaccc aaactgaagg tgagctggcg ggggctgggc    360

agacccatca gacccttgct gtactgtgct gtgctgtgct gtgctgtgct gtgctgtgct    420

ggtccatcct cagtcttgcc accgctggtg aggcaagcat cctgcctgtc tgagtggctt    480

tgaggattgg tgtgggtcgt ctctggcatg gttgatggtg gggtcccctg ggcaagcttc    540

ttctggggca agttgtaaac tgttagtgct ggcccctaga gccagacagc ctgggctcaa    600

gtctagactc ctttgtcacc tctgcacagg tctttttttg gcccagcttc cttgctgtag    660

tttctagcat aacaccaggg atgtggtggt gaaagttccg gaagtgttga gaactgctgc    720

tgtcagccca gggtgctccg ggtagtaaac gatagtgttg gttaccaggg ctctgctgcg    780

ccaaggcagt ggagggtgag tcctggcagc ccctgggtga ccacgcaggg gtctgacccg    840

ccagccttgt cctctccacc aggtatgtgc actgcgcgtg accagccggg cccgcagccg    900

catcctcagg gcagggggca agatcctcac tttcgaccag ctggccctgg actcccctaa    960

gggctgtggc actgtcctgc tctccggtga gtgatacgtg gtcgacgggt ttggactgag   1020

ctgtgtggct actggcagcc ttcaccctcc tggatctggg aggccagaag ctgggcgcca   1080

gatccctgtc tcacccggtt ctccttcccc ttccctaggt cctcgcaagg gccgagaggt   1140

gtaccggcat ttcggcaagg ccccaggaac cccgcacagc cacaccaagt gagtatcagg   1200

cccccagccc tgccctctcc ccagactcag cctgcagggc caggcctggc cacacttggg   1260

ctgcttctcc tatccctcgt accagccagc cccaggcctt ctggaactct cagctgcctc   1320

atcctgcctg cttttccctt caacactgct tggagctgtg ttttccaggg cctgagcagg   1380

catctcctgg ggagcatgca gttcaccggc ctttgccagc ccaggctggg accctccagg   1440

tggtggggca ggtgcttcca tagcccctcc tggctccttg gcttcccact ctgccaagct   1500

tttccagcag cattgactct cctggggctg aatgtgacag gcttgtggtg ttcctgtgcc   1560

actccacaat ggcctccttt aagagggccc ccctctcact ccctcctctc cccacagacc   1620

ctacgtccgc tccaagggcc ggaagttcga gcgtgccaga ggccgacggg ccagccgagg   1680

ctacaaaaac taaccctgga tcctactctc ttattaaaaa gatttttgct gacagtg      1737


<210>  9273
<211>  146
<212>  PRT
<213>  Homo sapiens

<400>  9273

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu Ser Leu Ser 
    50                  55                  60


Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn Lys Thr Ala 
65                  70                  75                  80


Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln Glu Val Pro 
                85                  90                  95


Lys Leu Lys Val Ser Trp Arg Gly Leu Gly Arg Pro Ile Arg Pro Leu 
            100                 105                 110


Leu Tyr Cys Ala Val Leu Cys Cys Ala Val Leu Cys Cys Ala Gly Pro 
        115                 120                 125


Ser Ser Val Leu Pro Pro Leu Val Arg Gln Ala Ser Cys Leu Ser Glu 
    130                 135                 140


Trp Leu 
145


<210>  9274
<211>  1433
<212>  DNA
<213>  Homo sapiens

<400>  9274
actgggcccg ccgggtcctc cgggagccac tgagaggccg tcggcgtcgg gccagagcgt     60

caccgcgcga cgcatcgtgc tagctacacg catctcgctc ccagatccct ttcttccgga    120

aagctatcga gaacacggcc tgggtagggc cagagaggcc cccgacgtgc tggcccttcc    180

ctcttggacg ttgcgcttgt tcctgcgctc tatgctctct gccgttatcg cccggctagt    240

cagtcgtcca actcaccaca gagaagtccg gatcgtggta gagcgccgcg tcgcacccat    300

gtgacgtcac ggcggcgcca ctcgcttgag gctttccccg cccaccccag cccgttctct    360

ctttccggac ctggccgagc aggaggcgcc atcatgggag tggacatccg ccataacaag    420

gaccgaaagg ttcggcgcaa ggagcccaag agccaggata tctacctgag gctgttggtc    480

aagttataca ggtttctggc cagaagaacc aactccacat tcaaccaggt tgtgttgaag    540

aggttgttta tgagtcgcac caaccggccg cctctgtccc tttcccggat gatccggaag    600

atgaagcttc ctggccggga aaacaagacg gccgtggttg tggggaccat aactgatgat    660

gtgcgggttc aggaggtacc caaactgaag gtatgtgcac tgcgcgtgac cagccgggcc    720

cgcagccgca tcctcagggc agggggcaag atcctcactt tcgaccagct ggccctggac    780

tcccctaagg gctgtggcac tgtcctgctc tccggtcctc gcaagggccg agaggtgtac    840

cggcatttcg gcaaggcccc aggaaccccg cacagccaca ccaagtgagt atcaggcccc    900

cagccctgcc ctctccccag actcagcctg cagggccagg cctggccaca cttgggctgc    960

ttctcctatc cctcgtacca gccagcccca ggccttctgg aactctcagc tgcctcatcc   1020

tgcctgcttt tcccttcaac actgcttgga gctgtgtttt ccagggcctg agcaggcatc   1080

tcctggggag catgcagttc accggccttt gccagcccag gctgggaccc tccaggtggt   1140

ggggcaggtg cttccatagc ccctcctggc tccttggctt cccactctgc caagcttttc   1200

cagcagcatt gactctcctg gggctgaatg tgacaggctt gtggtgttcc tgtgccactc   1260

cacaatggcc tcctttaaga gggcccccct ctcactccct cctctcccca cagaccctac   1320

gtccgctcca agggccggaa gttcgagcgt gccagaggcc gacgggccag ccgaggctac   1380

aaaaactaac cctggatcct actctcttat taaaaagatt tttgctgaca gtg          1433


<210>  9275
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  9275

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu Ser Leu Ser 
    50                  55                  60


Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn Lys Thr Ala 
65                  70                  75                  80


Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln Glu Val Pro 
                85                  90                  95


Lys Leu Lys Val Cys Ala Leu Arg Val Thr Ser Arg Ala Arg Ser Arg 
            100                 105                 110


Ile Leu Arg Ala Gly Gly Lys Ile Leu Thr Phe Asp Gln Leu Ala Leu 
        115                 120                 125


Asp Ser Pro Lys Gly Cys Gly Thr Val Leu Leu Ser Gly Pro Arg Lys 
    130                 135                 140


Gly Arg Glu Val Tyr Arg His Phe Gly Lys Ala Pro Gly Thr Pro His 
145                 150                 155                 160


Ser His Thr Lys 



<210>  9276
<211>  902
<212>  DNA
<213>  Homo sapiens

<400>  9276
actgggcccg ccgggtcctc cgggagccac tgagaggccg tcggcgtcgg gccagagcgt     60

caccgcgcga cgcatcgtgc tagctacacg catctcgctc ccagatccct ttcttccgga    120

aagctatcga gaacacggcc tgggtagggc cagagaggcc cccgacgtgc tggcccttcc    180

ctcttggacg ttgcgcttgt tcctgcgctc tatgctctct gccgttatcg cccggctagt    240

cagtcgtcca actcaccaca gagaagtccg gatcgtggta gagcgccgcg tcgcacccat    300

gtgacgtcac ggcggcgcca ctcgcttgag gctttccccg cccaccccag cccgttctct    360

ctttccggac ctggccgagc aggaggcgcc atcatgggag tggacatccg ccataacaag    420

gaccgaaagg ttcggcgcaa ggagcccaag agccaggata tctacctgag gctgttggtc    480

aagttataca ggtttctggc cagaagaacc aactccacat tcaaccaggt tgtgttgaag    540

aggttgttta tgagtcgcac caaccggccg cctctgtccc tttcccggat gatccggaag    600

atgaagcttc ctggccggga aaacaagacg gccgtggttg tggggaccat aactgatgat    660

gtgcgggttc aggaggtacc caaactgaag gtatgtgcac tgcgcgtgac cagccgggcc    720

cgcagccgca tcctcagggc agggggcaag atcctcactt tcgaccagct ggccctggac    780

tcaccctacg tccgctccaa gggccggaag ttcgagcgtg ccagaggccg acgggccagc    840

cgaggctaca aaaactaacc ctggatccta ctctcttatt aaaaagattt ttgctgacag    900

tg                                                                   902


<210>  9277
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  9277

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Arg Thr Asn Ser Thr Phe Asn Gln Val Val Leu 
        35                  40                  45


Lys Arg Leu Phe Met Ser Arg Thr Asn Arg Pro Pro Leu Ser Leu Ser 
    50                  55                  60


Arg Met Ile Arg Lys Met Lys Leu Pro Gly Arg Glu Asn Lys Thr Ala 
65                  70                  75                  80


Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val Gln Glu Val Pro 
                85                  90                  95


Lys Leu Lys Val Cys Ala Leu Arg Val Thr Ser Arg Ala Arg Ser Arg 
            100                 105                 110


Ile Leu Arg Ala Gly Gly Lys Ile Leu Thr Phe Asp Gln Leu Ala Leu 
        115                 120                 125


Asp Ser Pro Tyr Val Arg Ser Lys Gly Arg Lys Phe Glu Arg Ala Arg 
    130                 135                 140


Gly Arg Arg Ala Ser Arg Gly Tyr Lys Asn 
145                 150


<210>  9278
<211>  445
<212>  DNA
<213>  Homo sapiens

<400>  9278
ggccgagcag gaggcgccat catgggagtg gacatccgcc ataacaagga ccgaaaggtt     60

cggcgcaagg agcccaagag ccaggatatc tacctgaggc tgttggtcaa gttatacagg    120

tttctggcca gaagtatgtg cactgcgcgt gaccagccgg gcccgcagcc gcatcctcag    180

ggcagggggc aagatcctca ctttcgacca gctggccctg gactccccta agggctgtgg    240

cactgtcctg ctctccggtc ctcgcaaggg ccgagaggtg taccggcatt tcggcaaggc    300

cccaggaacc ccgcacagcc acaccaaacc ctacgtccgc tccaagggcc ggaagttcga    360

gcgtgccaga ggccgacggg ccagccgagg ctacaaaaac taaccctgga tcctactctc    420

ttattaaaaa gatttttgct gacag                                          445


<210>  9279
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  9279

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Leu Tyr 
            20                  25                  30


Arg Phe Leu Ala Arg Ser Met Cys Thr Ala Arg Asp Gln Pro Gly Pro 
        35                  40                  45


Gln Pro His Pro Gln Gly Arg Gly Gln Asp Pro His Phe Arg Pro Ala 
    50                  55                  60


Gly Pro Gly Leu Pro 
65


<210>  9280
<211>  813
<212>  DNA
<213>  Homo sapiens

<400>  9280
cctgggtgac cacgcagggg tctgacccgc cagccttgtc ctctccacca ggtatgtgca     60

ctgcgcgtga ccagccgggc ccgcagccgc atcctcaggg cagggggcaa gatcctcact    120

ttcgaccagc tggccctgga ctcccctaag ggctgtggca ctgtcctgct ctccggtgag    180

tgatacgtgg tcgacgggtt tggactgagc tgtgtggcta ctggcagcct tcaccctcct    240

ggatctggga ggccagaagc tgggcgccag atccctgtct cacccggttc tccttcccct    300

tccctaggtc ctcgcaaggg ccgagaggtg taccggcatt tcggcaaggc cccaggaacc    360

ccgcacagcc acaccaagtg agtatcaggc ccccagccct gccctctccc cagactcagc    420

ctgcagggcc aggcctggcc acacttgggc tgcttctcct atccctcgta ccagccagcc    480

ccaggccttc tggaactctc agctgcctca tcctgcctgc ttttcccttc aacactgctt    540

ggagctgtgt tttccagggc ctgagcaggc atctcctggg gagcatgcag ttcaccggcc    600

tttgccagcc caggctggga ccctccaggt ggtggggcag gtgcttccat agcccctcct    660

ggctccttgg cttcccactt ccctcctctc cccacagacc ctacgtccgc tccaagggcc    720

ggaagttcga gcgtgccaga ggccgacggg ccagccgagg ctacaaaaac taaccctgga    780

tcctactctc ttattaaaaa gatttttgct gac                                 813


<210>  9281
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  9281

Met Gln Phe Thr Gly Leu Cys Gln Pro Arg Leu Gly Pro Ser Arg Trp 
1               5                   10                  15


Trp Gly Arg Cys Phe His Ser Pro Ser Trp Leu Leu Gly Phe Pro Leu 
            20                  25                  30


Pro Ser Ser Pro His Arg Pro Tyr Val Arg Ser Lys Gly Arg Lys Phe 
        35                  40                  45


Glu Arg Ala Arg Gly Arg Arg Ala Ser Arg Gly Tyr Lys Asn 
    50                  55                  60


<210>  9282
<211>  1132
<212>  DNA
<213>  Homo sapiens

<400>  9282
ggatgcctca agcggggctg aatgtaaaca ccagaacaac ttacgacgta catcctcccc     60

accctaagat ccggaagatg aagcttcctg gccgggaaaa caagacggcc gtggttgtgg    120

ggaccataac tgatgatgtg cgggttcagg aggtacccaa actgaaggtg agctggcggg    180

ggctgggcag acccatcaga cccttgctgt actgtgctgt gctgtgctgt gctgtgctgt    240

gctgtgctgg tccatcctca gtcttgccac cgctggtgag gcaagcatcc tgcctgtctg    300

agtggctttg aggattggtg tgggtcgtct ctggcatggt tgatggtggg gtcccctggg    360

caagcttctt ctggggcaag ttgtaaactg ttagtgctgg cccctagagc cagacagcct    420

gggctcaagt ctagactcct ttgtcacctc tgcacaggtc tttttttggc ccagcttcct    480

tgctgtagtt tctagcataa caccagggat gtggtggtga aagttccgga agtgttgaga    540

actgctgctg tcagcccagg gtgctccggg tagtaaacga tagtgttggt taccagggct    600

ctgctgcgcc aaggcagtgg agggtgagtc ctggcagccc ctgggtgacc acgcaggggt    660

ctgacccgcc agccttgtcc tctccaccag gtatgtgcac tgcgcgtgac cagccgggcc    720

cgcagccgca tcctcagggc agggggcaag atcctcactt tcgaccagct ggccctggac    780

tcccctaagg gctgtggcac tgtcctgctc tccggtgagt gatacgtggt cgacgggttt    840

ggactgagct gtgtggctac tggcagcctt caccctcctg gatctgggag gccagaagct    900

gggcgccaga tccctgtctc acccggttct ccttcccctt ccctaggtcc tcgcaagggc    960

cgagaggtgt accggcattt cggcaaggcc ccaggaaccc cgcacagcca caccaaaccc   1020

tacgtccgct ccaagggccg gaagttcgag cgtgccagag gccgacgggc cagccgaggc   1080

tacaaaaact aaccctggat cctactctct tattaaaaag atttttgctg ac           1132


<210>  9283
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  9283

Met Pro Gln Ala Gly Leu Asn Val Asn Thr Arg Thr Thr Tyr Asp Val 
1               5                   10                  15


His Pro Pro His Pro Lys Ile Arg Lys Met Lys Leu Pro Gly Arg Glu 
            20                  25                  30


Asn Lys Thr Ala Val Val Val Gly Thr Ile Thr Asp Asp Val Arg Val 
        35                  40                  45


Gln Glu Val Pro Lys Leu Lys Val Ser Trp Arg Gly Leu Gly Arg Pro 
    50                  55                  60


Ile Arg Pro Leu Leu Tyr Cys Ala Val Leu Cys Cys Ala Val Leu Cys 
65                  70                  75                  80


Cys Ala Gly Pro Ser Ser Val Leu Pro Pro Leu Val Arg Gln Ala Ser 
                85                  90                  95


Cys Leu Ser Glu Trp Leu 
            100


<210>  9284
<211>  1338
<212>  DNA
<213>  Homo sapiens

<400>  9284
ctccgggtat gggaaccagt tttgataaca ttgttgcaaa atacaagttg taaagaattg     60

acctttttgt attaagttaa tatgattgct gtgttacgat gtttcagggt tctgtgtgcc    120

atgggctgaa ggctttgtaa acagcccctt tttacagagg gatcagtggc agcccacagg    180

tctcctggtg gtgggcctgg gatttgagct ggtgtgttca gacctgggct tgtgtcccag    240

ctctcagttt cagaaataag taataattgg ctatggttgg gggtaattgg gtccatggtt    300

gcctcttcac ccccacaggg agtggacatc cgccataaca aggaccgaaa ggttcggcgc    360

aaggagccca agagccagga tatctacctg aggctgttgg tcaaggtgag gctgggccct    420

gaggtctttg ggaagggtca ccccaggtct gacttgcaga tcctccattc tagtgctggc    480

accaagctcc tcccaggggc ctgcagagca gtctcgggtc tctggttctg ttccagggtc    540

tcctgcattt gtattttcag cctctaggct gtgtacagct cgggagtgga gccaggattt    600

tctaggtcct tggccaggaa ggacctgggc cagctttctc cctctaggtc ggtgggttgg    660

gggaaaggga taaagattat tttagtccag atcatcatgt gtttgcccct tcactggaag    720

gctgcggggg agcaggctgt cccagcttct cactgtcttc ccgtccctcc agttatacag    780

gtttctggcc agaagaacca actccacatt caaccaggtt gtgttgaaga ggttgtttat    840

gagtcgcacc aaccggccgc ctctgtccct ttcccggatg gtgagtggct ggtccagaga    900

gcacggtaga cctgggagcc gctgggtctt gtctgtctgg aagggaggca ggacttggag    960

ctctgggagc aaccagggca tcaagggttt gtctcagcca gtcgcgagcg tagagcttgg   1020

actgttggtt ggaactgagt gtccatgggc agtgggcaag tctcctggtc ctcctctcct   1080

tctctttgtg aggtggaggt gtcctggtgg cttcaggaga ttgccccaag tcataactga   1140

gttttatgtc aaaggctctg ctgagggagg ccctattgaa cagtctgcat tttttttttt   1200

atctggagct ttccccagct ggaccctacg tccgctccaa gggccggaag ttcgagcgtg   1260

ccagaggccg acgggccagc cgaggctaca aaaactaacc ctggatccta ctctcttatt   1320

aaaaagattt ttgctgac                                                 1338


<210>  9285
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  9285

Met Ser Arg Thr Asn Arg Pro Pro Leu Ser Leu Ser Arg Met Val Ser 
1               5                   10                  15


Gly Trp Ser Arg Glu His Gly Arg Pro Gly Ser Arg Trp Val Leu Ser 
            20                  25                  30


Val Trp Lys Gly Gly Arg Thr Trp Ser Ser Gly Ser Asn Gln Gly Ile 
        35                  40                  45


Lys Gly Leu Ser Gln Pro Val Ala Ser Val Glu Leu Gly Leu Leu Val 
    50                  55                  60


Gly Thr Glu Cys Pro Trp Ala Val Gly Lys Ser Pro Gly Pro Pro Leu 
65                  70                  75                  80


Leu Leu Phe Val Arg Trp Arg Cys Pro Gly Gly Phe Arg Arg Leu Pro 
                85                  90                  95


Gln Val Ile Thr Glu Phe Tyr Val Lys Gly Ser Ala Glu Gly Gly Pro 
            100                 105                 110


Ile Glu Gln Ser Ala Phe Phe Phe Leu Ser Gly Ala Phe Pro Ser Trp 
        115                 120                 125


Thr Leu Arg Pro Leu Gln Gly Pro Glu Val Arg Ala Cys Gln Arg Pro 
    130                 135                 140


Thr Gly Gln Pro Arg Leu Gln Lys Leu Thr Leu Asp Pro Thr Leu Leu 
145                 150                 155                 160


Leu Lys Arg Phe Leu 
                165


<210>  9286
<211>  879
<212>  DNA
<213>  Homo sapiens

<400>  9286
cgttctctct ttccggacct ggccgagcag gaggcgccat catgggagtg gacatccgcc     60

ataacaagga ccgaaaggtt cggcgcaagg agcccaagag ccaggatatc tacctgaggc    120

tgttggtcaa ggtgaggctg ggccctgagg tctttgggaa gggtcacccc aggtctgact    180

tgcagatcct ccattctagt gctggcacca agctcctccc aggggcctgc agagcagtct    240

cgggtctctg gttctgttcc agggtctcct gcatttgtat tttcagcctc taggctgtgt    300

acagctcggg agtggagcca ggattttcta ggtccttggc caggaaggac ctgggccagc    360

tttctccctc taggtcggtg ggttggggga aagggataaa gattatttta gtccagatca    420

tcatgtgttt gccccttcac tggaaggctg cgggggagca ggctgtccca gcttctcact    480

gtcttcccgt ccctccagtt atacaggttt ctggccagaa gaaccaactc cacattcaac    540

caggttgtgt tgaagaggtt gtttatgagt cgcaccaacc ggccgcctct gtccctttcc    600

cggatggtga gtggctggtc cagagagcac ggtagacctg ggagccgctg ggtcttgtct    660

gtctggaagg gaggcaggac ttggagctct gggagcaacc agggcatcaa gggtttgtct    720

cagccagtcg cgagcgtaga gcttggactg ttggttggaa ctgagtgtcc atgggcagtg    780

ggcaagtctc ctggtcctcc tctccttctc tttgtgaggt ggaggtgtcc tggtggcttc    840

aggagattgc cccaagtcat aactgagttt tatgtcaaa                           879


<210>  9287
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  9287

Met Gly Val Asp Ile Arg His Asn Lys Asp Arg Lys Val Arg Arg Lys 
1               5                   10                  15


Glu Pro Lys Ser Gln Asp Ile Tyr Leu Arg Leu Leu Val Lys Val Arg 
            20                  25                  30


Leu Gly Pro Glu Val Phe Gly Lys Gly His Pro Arg Ser Asp Leu Gln 
        35                  40                  45


Ile Leu His Ser Ser Ala Gly Thr Lys Leu Leu Pro Gly Ala Cys Arg 
    50                  55                  60


Ala Val Ser Gly Leu Trp Phe Cys Ser Arg Val Ser Cys Ile Cys Ile 
65                  70                  75                  80


Phe Ser Leu 



<210>  9288
<211>  2804
<212>  DNA
<213>  Homo sapiens

<400>  9288
ctctgtggtg agttggacga ctgactagcc gggcgataac ggcagagagc atagagcgca     60

ggaacaagcg caacgtccaa gagggaaggg ccagcacgtc gggggcctct ctggccctac    120

ccaggccgtg ttctcgatag ctttccggaa gaaagggatc tgggagcgag atgcgtgtag    180

ctagcacgat gcgtcgcgcg gtgacgctct ggcccgacgc cgacggcctc tcagtggctc    240

ccggaggacc cggcgggccc agtgttggag agctgaaggt caggccagga cagtgagacc    300

tgactccttg ctcctaccag cctactatgg cttaagaccc agggccaggg tcccgttgat    360

gtaacagagc agaggaccag cagatgaatg gacaccttga agcagaggag cagcaggacc    420

agaggccaga ccaggagctg accgggagct ggggccacgg gcctaggagc accctggtca    480

gggctaaggc catggccccg cccccaccgc cactggctgc cagcaccccg ctcctccatg    540

gcgagtttgg ctcctaccca gcccgaggcc cacgctttgc cctcaccctt acatcgcagg    600

ccctgcacat acagcggctg ccccctcaga ctcagcggcc tacttctgca tctacaccta    660

ccctcggggc cggcgcgggg cccggcgcag agccactcgc accttccggg cagatggggc    720

cgccacctac gaagagaacc gtgccgaggc ccagcgctgg gccactgccc tcacctgtct    780

gctccgagga ctgccactgc ccggggatgg ggagatcacc cctgacctgc tacctcggcc    840

gccccggttg cttctattgg tcaatccctt tgggggtcgg ggcctggcct ggcagtggtg    900

taagaaccac gtgcttccca tgatctctga agctgggctg tccttcaacc tcatccagac    960

agaacgacag aaccacgccc gggagctggt ccaggggctg agcctgagtg agtgggatgg   1020

catcgtcacg gtctcgggag acgggctgct ccatgaggtg ctgaacgggc tcctagatcg   1080

ccctgactgg gaggaagctg tgaagatgcc tgtgggcatc ctcccctgcg gctcgggcaa   1140

cgcgctggcc ggagcagtga accagcacgg gggatttgag ccagccctgg gcctcgacct   1200

gttgctcaac tgctcactgt tgctgtgccg gggtggtggc cacccactgg acctgctctc   1260

cgtgacgctg gcctcgggct cccgctgttt ctccttcctg tctgtggcct ggggcttcgt   1320

gtcagatgtg gatatccaga gcgagcgctt cagggccttg ggcagtgccc gcttcacact   1380

gggcacggtg ctgggcctcg ccacactgca cacctaccgc ggacgcctct cctacctccc   1440

cgccactgtg gaacctgcct cgcccacccc tgcccatagc ctgcctcgtg ccaagtcgga   1500

gctgacccta accccagaag aacccctgcc catcctgtcc ctcaacggtg ggggcccaga   1560

gctggctggg gactggggtg gggctgggga tgctccgctg tccccggacc cactgctgtc   1620

ttcacctcct ggctctccca aggcagctct acactcaccc gtctccgaag gggcccccgt   1680

aattccccca tcctctgggc tcccacttcc cacccctgat gcccgggtag gggcctccac   1740

ctgcggcccg cccgaccacc tgctgcctcc gctgggcacc ccgctgcccc cagactgggt   1800

gacgctggag ggggactttg tgctcatgtt ggccatctcg cccagccacc taggcgctga   1860

cctggtggca gctccgcatg cgcgcttcga cgacggcctg gtgcacctgt gctgggtgcg   1920

tagcggcatc tcgcgggctg cgctgctgcg ccttttcttg gccatggagc gtggtagcca   1980

cttcagcctg ggctgtccgc agctgggcta cgccgcggcc cgtgccttcc gcctagagcc   2040

gctcacacca cgcggcgtgc tcacagtgga cggggagcag gtggagtatg ggccgctaca   2100

ggcacagatg caccctggca tcggtacact gctcactggg cctcctggct gcccggggcg   2160

ggagccctga aactaaacaa gcttggtacc cgccgggggc ggggcctaca ttccaatggg   2220

gcggagcctg agctaggggg tgtggcctgg ctgctagagt tgtggtggca ggggccctgg   2280

ccccgtctca ggattgcgct cgctttcatg ggaccagacg tgatgctgga aggtgggcgt   2340

cgtcacggtt aaagagaaat gggctcgtcc cgagggtagt gcctgatcaa tgagggcggg   2400

gcctggcgtc tgatctgggg ccgcccttac ggggcagggc tcagtcctga cgcttgccac   2460

ctgctcctac ccggccagga tggctgaggg cggagtctat tttacgcgtc gcccaatgac   2520

aggacctgga atgtactggc tggggtaggc ctcagtgagt cggccggtca gggcccgcag   2580

cctcgcccca tccactccgg tgcctccatt tagctggcca atcagcccag gaggggcagg   2640

ttccccgggg ccggcgctag gatttgcact aatgttcctc tccccgcggg tgggggcggg   2700

gaaattcata tcccctgttc gtctcatgcg cgtcctccgt ccccaatcta aaaagcaatt   2760

gaaaaggtct atgcaataaa ggcagtcgct tcattcctct caga                    2804


<210>  9289
<211>  416
<212>  PRT
<213>  Homo sapiens

<400>  9289

Met Ile Ser Glu Ala Gly Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg 
1               5                   10                  15


Gln Asn His Ala Arg Glu Leu Val Gln Gly Leu Ser Leu Ser Glu Trp 
            20                  25                  30


Asp Gly Ile Val Thr Val Ser Gly Asp Gly Leu Leu His Glu Val Leu 
        35                  40                  45


Asn Gly Leu Leu Asp Arg Pro Asp Trp Glu Glu Ala Val Lys Met Pro 
    50                  55                  60


Val Gly Ile Leu Pro Cys Gly Ser Gly Asn Ala Leu Ala Gly Ala Val 
65                  70                  75                  80


Asn Gln His Gly Gly Phe Glu Pro Ala Leu Gly Leu Asp Leu Leu Leu 
                85                  90                  95


Asn Cys Ser Leu Leu Leu Cys Arg Gly Gly Gly His Pro Leu Asp Leu 
            100                 105                 110


Leu Ser Val Thr Leu Ala Ser Gly Ser Arg Cys Phe Ser Phe Leu Ser 
        115                 120                 125


Val Ala Trp Gly Phe Val Ser Asp Val Asp Ile Gln Ser Glu Arg Phe 
    130                 135                 140


Arg Ala Leu Gly Ser Ala Arg Phe Thr Leu Gly Thr Val Leu Gly Leu 
145                 150                 155                 160


Ala Thr Leu His Thr Tyr Arg Gly Arg Leu Ser Tyr Leu Pro Ala Thr 
                165                 170                 175


Val Glu Pro Ala Ser Pro Thr Pro Ala His Ser Leu Pro Arg Ala Lys 
            180                 185                 190


Ser Glu Leu Thr Leu Thr Pro Glu Glu Pro Leu Pro Ile Leu Ser Leu 
        195                 200                 205


Asn Gly Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly Gly Ala Gly Asp 
    210                 215                 220


Ala Pro Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro Pro Gly Ser Pro 
225                 230                 235                 240


Lys Ala Ala Leu His Ser Pro Val Ser Glu Gly Ala Pro Val Ile Pro 
                245                 250                 255


Pro Ser Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala Arg Val Gly Ala 
            260                 265                 270


Ser Thr Cys Gly Pro Pro Asp His Leu Leu Pro Pro Leu Gly Thr Pro 
        275                 280                 285


Leu Pro Pro Asp Trp Val Thr Leu Glu Gly Asp Phe Val Leu Met Leu 
    290                 295                 300


Ala Ile Ser Pro Ser His Leu Gly Ala Asp Leu Val Ala Ala Pro His 
305                 310                 315                 320


Ala Arg Phe Asp Asp Gly Leu Val His Leu Cys Trp Val Arg Ser Gly 
                325                 330                 335


Ile Ser Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala Met Glu Arg Gly 
            340                 345                 350


Ser His Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr Ala Ala Ala Arg 
        355                 360                 365


Ala Phe Arg Leu Glu Pro Leu Thr Pro Arg Gly Val Leu Thr Val Asp 
    370                 375                 380


Gly Glu Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln Met His Pro Gly 
385                 390                 395                 400


Ile Gly Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro Gly Arg Glu Pro 
                405                 410                 415


<210>  9290
<211>  2965
<212>  DNA
<213>  Homo sapiens

<400>  9290
cgactgacta gccgggcgat aacggcagag agcatagagc gcaggaacaa gcgcaacgtc     60

caagagggaa gggccagcac gtcgggggcc tctctggccc tacccaggcc gtgttctcga    120

tagctttccg gaagaaaggg atctgggagc gagatgcgtg tagctagcac gatgcgtcgc    180

gcggtgacgc tctggcccga cgccgacggc ctctcagtgg ctcccggagg acccggcggg    240

cccagtgttg gagagctgaa ggtcaggcca ggacagtgag acctgactcc ttgctcctac    300

cagcctacta tggcttaaga cccagggcca gggtcccgtt gatgtaacag agcagaggac    360

cagcagatga atggacacct tgaagcagag gagcagcagg accagaggcc agaccaggag    420

ctgaccggga gctggggcca cgggcctagg agcaccctgg tcagggctaa ggccatggcc    480

ccgcccccac cgccactggc tgccagcacc ccgctcctcc atggcgagtt tggctcctac    540

ccagcccgag gcccacgctt tgccctcacc cttacatcgc aggccctgca catacagcgg    600

ctgcgcccca aacctgaagc caggccccgg ggtggcctgg tcccgttggc cgaggtctca    660

ggctgctgca ccctgcgaag ccgcagcccc tcagactcag cggcctactt ctgcatctac    720

acctaccctc ggggccggcg cggggcccgg cgcagagcca ctcgcacctt ccgggcagat    780

ggggccgcca cctacgaaga gaaccgtgcc gaggcccagc gctgggccac tgccctcacc    840

tgtctgctcc gaggactgcc actgcccggg gatggggaga tcacccctga cctgctacct    900

cggccgcccc ggttgcttct attggtcaat ccctttgggg gtcggggcct ggcctggcag    960

tggtgtaaga accacgtgct tcccatgatc tctgaagctg ggctgtcctt caacctcatc   1020

cagacagaac gacagaacca cgcccgggag ctggtccagg ggctgagcct gagtgagtgg   1080

gatggcatcg tcacggtctc gggagacggg ctgctccatg aggtgctgaa cgggctccta   1140

gatcgccctg actgggagga agctgtgaag atgcctgtgg gcatcctccc ctgcggctcg   1200

ggcaacgcgc tggccggagc agtgaaccag cacgggggat ttgagccagc cctgggcctc   1260

gacctgttgc tcaactgctc actgttgctg tgccggggtg gtggccaccc actggacctg   1320

ctctccgtga cgctggcctc gggctcccgc tgtttctcct tcctgtctgt ggcctggggc   1380

ttcgtgtcag atgtggatat ccagagcgag cgcttcaggg ccttgggcag tgcccgcttc   1440

acactgggca cggtgctggg cctcgccaca ctgcacacct accgcggacg cctctcctac   1500

ctccccgcca ctgtggaacc tgcctcgccc acccctgccc atagcctgcc tcgtgccaag   1560

tcggagctga ccctaacccc agacccagcc ccgcccatgg cccactcacc cctgcatcgt   1620

tctgtgtctg acctgcctct tcccctgccc cagcctgccc tggcctctcc tggctcgcca   1680

gaacccctgc ccatcctgtc cctcaacggt gggggcccag agctggctgg ggactggggt   1740

ggggctgggg atgctccgct gtccccggac ccactgctgt cttcacctcc tggctctccc   1800

aaggcagctc tacactcacc cgtctccgaa ggggcccccg taattccccc atcctctggg   1860

ctcccacttc ccacccctga tgcccgggta ggggcctcca cctgcggccc gcccgaccac   1920

ctgctgcctc cgctgggcac cccgctgccc ccagactggg tgacgctgga gggggacttt   1980

gtgctcatgt tggccatctc gcccagccac ctaggcgctg acctggtggc agctccgcat   2040

gcgcgcttcg acgacggcct ggtgcacctg tgctgggtgc gtagcggcat ctcgcgggct   2100

gcgctgctgc gccttttctt ggccatggag cgtggtagcc acttcagcct gggctgtccg   2160

cagctgggct acgccgcggc ccgtgccttc cgcctagagc cgctcacacc acgcggcgtg   2220

ctcacagtgg acggggagca ggtggagtat gggccgctac aggcacagat gcaccctggc   2280

atcggtacac tgctcactgg gcctcctggc tgcccggggc gggagccctg aaactaaaca   2340

agcttggtac ccgccggggg cggggcctac attccaatgg ggcggagcct gagctagggg   2400

gtgtggcctg gctgctagag ttgtggtggc aggggccctg gccccgtctc aggattgcgc   2460

tcgctttcat gggaccagac gtgatgctgg aaggtgggcg tcgtcacggt taaagagaaa   2520

tgggctcgtc ccgagggtag tgcctgatca atgagggcgg ggcctggcgt ctgatctggg   2580

gccgccctta cggggcaggg ctcagtcctg acgcttgcca cctgctccta cccggccagg   2640

atggctgagg gcggagtcta ttttacgcgt cgcccaatga caggacctgg aatgtactgg   2700

ctggggtagg cctcagtgag tcggccggtc agggcccgca gcctcgcccc atccactccg   2760

gtgcctccat ttagctggcc aatcagccca ggaggggcag gttccccggg gccggcgcta   2820

ggatttgcac taatgttcct ctccccgcgg gtgggggcgg ggaaattcat atcccctgtt   2880

cgtctcatgc gcgtcctccg tccccaatct aaaaagcaat tgaaaaggtc tatgcaataa   2940

aggcagtcgc ttcattcctc tcaga                                         2965


<210>  9291
<211>  654
<212>  PRT
<213>  Homo sapiens

<400>  9291

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Glu Ile Thr Pro Asp Leu 
                165                 170                 175


Leu Pro Arg Pro Pro Arg Leu Leu Leu Leu Val Asn Pro Phe Gly Gly 
            180                 185                 190


Arg Gly Leu Ala Trp Gln Trp Cys Lys Asn His Val Leu Pro Met Ile 
        195                 200                 205


Ser Glu Ala Gly Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg Gln Asn 
    210                 215                 220


His Ala Arg Glu Leu Val Gln Gly Leu Ser Leu Ser Glu Trp Asp Gly 
225                 230                 235                 240


Ile Val Thr Val Ser Gly Asp Gly Leu Leu His Glu Val Leu Asn Gly 
                245                 250                 255


Leu Leu Asp Arg Pro Asp Trp Glu Glu Ala Val Lys Met Pro Val Gly 
            260                 265                 270


Ile Leu Pro Cys Gly Ser Gly Asn Ala Leu Ala Gly Ala Val Asn Gln 
        275                 280                 285


His Gly Gly Phe Glu Pro Ala Leu Gly Leu Asp Leu Leu Leu Asn Cys 
    290                 295                 300


Ser Leu Leu Leu Cys Arg Gly Gly Gly His Pro Leu Asp Leu Leu Ser 
305                 310                 315                 320


Val Thr Leu Ala Ser Gly Ser Arg Cys Phe Ser Phe Leu Ser Val Ala 
                325                 330                 335


Trp Gly Phe Val Ser Asp Val Asp Ile Gln Ser Glu Arg Phe Arg Ala 
            340                 345                 350


Leu Gly Ser Ala Arg Phe Thr Leu Gly Thr Val Leu Gly Leu Ala Thr 
        355                 360                 365


Leu His Thr Tyr Arg Gly Arg Leu Ser Tyr Leu Pro Ala Thr Val Glu 
    370                 375                 380


Pro Ala Ser Pro Thr Pro Ala His Ser Leu Pro Arg Ala Lys Ser Glu 
385                 390                 395                 400


Leu Thr Leu Thr Pro Asp Pro Ala Pro Pro Met Ala His Ser Pro Leu 
                405                 410                 415


His Arg Ser Val Ser Asp Leu Pro Leu Pro Leu Pro Gln Pro Ala Leu 
            420                 425                 430


Ala Ser Pro Gly Ser Pro Glu Pro Leu Pro Ile Leu Ser Leu Asn Gly 
        435                 440                 445


Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly Gly Ala Gly Asp Ala Pro 
    450                 455                 460


Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro Pro Gly Ser Pro Lys Ala 
465                 470                 475                 480


Ala Leu His Ser Pro Val Ser Glu Gly Ala Pro Val Ile Pro Pro Ser 
                485                 490                 495


Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala Arg Val Gly Ala Ser Thr 
            500                 505                 510


Cys Gly Pro Pro Asp His Leu Leu Pro Pro Leu Gly Thr Pro Leu Pro 
        515                 520                 525


Pro Asp Trp Val Thr Leu Glu Gly Asp Phe Val Leu Met Leu Ala Ile 
    530                 535                 540


Ser Pro Ser His Leu Gly Ala Asp Leu Val Ala Ala Pro His Ala Arg 
545                 550                 555                 560


Phe Asp Asp Gly Leu Val His Leu Cys Trp Val Arg Ser Gly Ile Ser 
                565                 570                 575


Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala Met Glu Arg Gly Ser His 
            580                 585                 590


Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr Ala Ala Ala Arg Ala Phe 
        595                 600                 605


Arg Leu Glu Pro Leu Thr Pro Arg Gly Val Leu Thr Val Asp Gly Glu 
    610                 615                 620


Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln Met His Pro Gly Ile Gly 
625                 630                 635                 640


Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro Gly Arg Glu Pro 
                645                 650


<210>  9292
<211>  755
<212>  DNA
<213>  Homo sapiens

<400>  9292
tgactagccg ggcgataacg gcagagagca tagagcgcag gaacaagcgc aacgtccaag     60

agggaagggc cagcacgtcg ggggcctctc tggccctacc caggccgtgt tctcgatagc    120

tttccggaag aaagggatct gggagcgaga tgcgtgtagc tagcacgatg cgtcgcgcgg    180

tgacgctctg gcccgacgcc gacggcctct cagtggctcc cggaggaccc ggcgggccca    240

gtgttggaga gctgaaggtc aggccaggac agtgagacct gactccttgc tcctaccagc    300

ctactatggc ttaagaccca gggccagggt cccgttgatg taacagagca gaggaccagc    360

agatgaatgg acaccttgaa gcagaggagc agcaggacca gaggccagac caggagctga    420

ccgggagctg gggccacggg cctaggagca ccctggtcag ggctaaggcc atggccccgc    480

ccccaccgcc actggctgcc agcaccccgc tcctccatgg cgagtttggc tcctacccag    540

cccgaggccc acgctttgcc ctcaccctta catcgcaggc cctgcacata cagcggctgc    600

gccccaaacc tgaagccagg ccccggggtg gcctggtccc gttggccgag gtctcaggct    660

gctgcaccct gcgaagccgc agcccctcag actcagcggc ctacttctgc atctacacct    720

acgaagagaa ccgtgccgag gcccagcgct gggcc                               755


<210>  9293
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  9293

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Glu Glu Asn Arg Ala Glu Ala Gln 
        115                 120                 125


Arg Trp 
    130


<210>  9294
<211>  378
<212>  DNA
<213>  Homo sapiens

<400>  9294
gtgttctcga tagctttccg gaagaaaggg atctgggagc gagatgcgtg tagctagcac     60

gatgcgtcgc gcggtgacgc tctggcccga cgccgacggc ctctcagtgg ctcccggagg    120

acccggcggg cccagtgttg gagagctgaa ggtcaggcca ggacagtgag acctgactcc    180

ttgctcctac cagcctacta tggcttaaga cccagggcca gggtcccgtt gatgtaacag    240

agcagaggac cagcagatga atggacacct tgaagcagag gagcagcagg accaggtaag    300

ggaccatcta aaagccaaga tcctcatact gtggaaagac aaaatctgaa gcttttcttt    360

aaaaaaaaaa aaaaaaaa                                                  378


<210>  9295
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9295

Met Arg Val Ala Ser Thr Met Arg Arg Ala Val Thr Leu Trp Pro Asp 
1               5                   10                  15


Ala Asp Gly Leu Ser Val Ala Pro Gly Gly Pro Gly Gly Pro Ser Val 
            20                  25                  30


Gly Glu Leu Lys Val Arg Pro Gly Gln 
        35                  40


<210>  9296
<211>  636
<212>  DNA
<213>  Homo sapiens

<400>  9296
ataaacaaga gaccaaaaca gtgggattga gaatgtgcaa gtatgaggat cttggctttt     60

agatggtccc ttacctggtc ctgctgctcc tctgcttcaa ggtgtccatt catctgctgg    120

tcctctgctc tgttacatca acgggaccct ggccctgggt cttaagccat agtaggctgg    180

taggagcaag gagtcaggtc tcactgtcct ggcctgacct tcagctctgt ggaggagagg    240

tcagggaagg gccatctagg ggccggggga gaaggagaag cggaactcaa aggatgggaa    300

tacaggatgc tatagattga ggtgcagcaa gatcatctcg ggttagacct taagtaggac    360

ttcccaagca gcggctgcgc ctacgaagtg cagcgcgaga tcagggagcg gtgaacctga    420

taaggaaacg cccgaagcgt ggggtcggaa atttccagat gccccgacta gccctgccag    480

ccccgcctcc tcacctccaa cactgggccc gccgggtcct ccgggagcca ctgagaggcc    540

gtcggcgtcg ggccagagcg tcaccgcgcg acgcatcgtg ctagctacac gcatctcgct    600

cccagatccc tttcttccgg aaagctatcg agaaca                              636


<210>  9297
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  9297

Met Val Pro Tyr Leu Val Leu Leu Leu Leu Cys Phe Lys Val Ser Ile 
1               5                   10                  15


His Leu Leu Val Leu Cys Ser Val Thr Ser Thr Gly Pro Trp Pro Trp 
            20                  25                  30


Val Leu Ser His Ser Arg Leu Val Gly Ala Arg Ser Gln Val Ser Leu 
        35                  40                  45


Ser Trp Pro Asp Leu Gln Leu Cys Gly Gly Glu Val Arg Glu Gly Pro 
    50                  55                  60


Ser Arg Gly Arg Gly Arg Arg Arg Ser Gly Thr Gln Arg Met Gly Ile 
65                  70                  75                  80


Gln Asp Ala Ile Asp 
                85


<210>  9298
<211>  820
<212>  DNA
<213>  Homo sapiens

<400>  9298
agctttccgg aagaaaggga tctgggagcg agatgcgtgt agctagcacg atgcgtcgcg     60

cggtgacgct ctggcccgac gccgacggcc tctcagtggc tcccggagga cccggcgggc    120

ccagtgttgg agagctgaag gtcaggccag gacagtgaga cctgactcct tgctcctacc    180

agcctactat ggcttaagac ccagggccag ggtcccgttg atgtaacaga gcagaggacc    240

agcagatgaa tggacacctt gaagcagagg agcagcagga ccagaggcca gaccaggagc    300

tgaccgggag ctggggccac gggcctagga gcaccctggt cagggctaag gccatggccc    360

cgcccccacc gccactggct gccagcaccc cgctcctcca tggcgagttt ggctcctacc    420

cagcccgagg cccacgcttt gccctcaccc ttacatcgca ggccctgcac atacagcggc    480

tgcgccccaa acctgaagcc aggccccggg gtggcctggt cccgttggcc gaggtctcag    540

gctgctgcac cctgcgaagc cgcagcccct cagactcagc ggcctacttc tgcatctaca    600

cctaccctcg gggccggcgc ggggcccggc gcagagccac tcgcaccttc cgggcagatg    660

gggccgccac ctacgaagag aaccgtgccg aggcccagcg ctgggccact gccctcacct    720

gtctgctccg aggactgcca ctgcccgggg atgggggtga ggtgctgggc agctgctcta    780

tcctggagcc accttggtgt ctctgcagaa tttcctccat                          820


<210>  9299
<211>  190
<212>  PRT
<213>  Homo sapiens

<400>  9299

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser 
                165                 170                 175


Cys Ser Ile Leu Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser 
            180                 185                 190


<210>  9300
<211>  544
<212>  DNA
<213>  Homo sapiens

<400>  9300
atctgggagc gagatgcgtg tagctagcac gatgcgtcgc gcggtgacgc tctggcccga     60

cgccgacggc ctctcagtgg ctcccggagg acccggcggg cccagtgttg gagagctgaa    120

ggtcaggcca ggacagtgag acctgactcc ttgctcctac cagcctacta tggcttaaga    180

cccagggcca gggtcccgtt gatgtaacag acccgaggcc cacgctttgc cctcaccctt    240

acatcgcagg ccctgcacat acagcggctg cgccccaaac ctgaagccag gccccggggt    300

ggcctggtcc cgttggccga ggtctcaggc tgctgcaccc tgcgaagccg cagcccctca    360

gactcagcgg cctacttctg catctacacc taccctcggg gccggcgcgg ggcccggcgc    420

agagccactc gcaccttccg ggcagatggg gccgccacct acgaagagaa ccgtgccgag    480

gcccagcgct gggccactgc cctcacctgt ctgctccgag gactgccact gcccggggat    540

gggg                                                                 544


<210>  9301
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9301

Met Arg Val Ala Ser Thr Met Arg Arg Ala Val Thr Leu Trp Pro Asp 
1               5                   10                  15


Ala Asp Gly Leu Ser Val Ala Pro Gly Gly Pro Gly Gly Pro Ser Val 
            20                  25                  30


Gly Glu Leu Lys Val Arg Pro Gly Gln 
        35                  40


<210>  9302
<211>  899
<212>  DNA
<213>  Homo sapiens

<400>  9302
gtagctagca cgatgcgtcg cgcggtgacg ctctggcccg acgccgacgg cctctcagtg     60

gctcccggag gacccggcgg gcccagtgtt ggagagctga aggtcaggcc aggacagtga    120

gacctgactc cttgctccta ccagcctact atggcttaag acccagggcc agggtcccgt    180

tgatgtaaca gagcagagga ccagcagatg aatggacacc ttgaagcaga ggagcagcag    240

gaccagagtc ttggtctgtt gcccaggctg gagtgcagtg gcatcatctc ggctcactgt    300

aacctccgcc tcttgggttc aagcgatctc ctgcctcagc ctcctgagta gctgggatta    360

cagaggccag accaggagct gaccgggagc tggggccacg ggcctaggag caccctggtc    420

agggctaagg ccatggcccc gcccccaccg ccactggctg ccagcacccc gctcctccat    480

ggcgagtttg gctcctaccc agcccgaggc ccacgctttg ccctcaccct tacatcgcag    540

gccctgcaca tacagcggct gcgccccaaa cctgaagcca ggccccgggg tggcctggtc    600

ccgttggccg aggtctcagg ctgctgcacc ctgcgaagcc gcagcccctc agactcagcg    660

gcctacttct gcatctacac ctaccctcgg ggccggcgcg gggcccggcg cagagccact    720

cgcaccttcc gggcagatgg ggccgccacc tacgaagaga accgtgccga ggcccagcgc    780

tgggccactg ccctcacctg tctgctccga ggactgccac tgcccgggga tgggggtgag    840

gtgctgggca gctgctctat cctggagcca ccttggtgtc tctgcagaat ttcctccat     899


<210>  9303
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  9303

Met Asp Thr Leu Lys Gln Arg Ser Ser Arg Thr Arg Val Leu Val Cys 
1               5                   10                  15


Cys Pro Gly Trp Ser Ala Val Ala Ser Ser Arg Leu Thr Val Thr Ser 
            20                  25                  30


Ala Ser Trp Val Gln Ala Ile Ser Cys Leu Ser Leu Leu Ser Ser Trp 
        35                  40                  45


Asp Tyr Arg Gly Gln Thr Arg Ser 
    50                  55


<210>  9304
<211>  539
<212>  DNA
<213>  Homo sapiens

<400>  9304
gtagctagca cgatgcgtcg cgcggtgacg ctctggcccg acgccgacgg cctctcagtg     60

gctcccggag gacccggcgg gcccagtgtt ggagagctga aggtcaggcc aggacagtga    120

gacctgactc cttgctccta ccagcctact atggcttaag acccagggcc agggtcccgt    180

tgatgtaaca gagcagagga ccagcagatg aatggacacc ttgaagcaga ggagcagcag    240

gaccagagat cacccctgac ctgctacctc ggccgccccg gttgcttcta ttggtcaatc    300

cctttggggg tcggggcctg gcctggcagt ggtgtaagaa ccacgtgctt cccatgatct    360

ctgaagctgg gctgtccttc aacctcatcc agacagaacg acagaaccac gcccgggagc    420

tggtccaggg gctgagcctg agtgagtggg atggcatcgt cacggtctcg ggagacgggc    480

tgctccatga ggtagagcag gagcaccctg cccctagccc tgggccctgg gggactata     539


<210>  9305
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  9305

Met Ile Ser Glu Ala Gly Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg 
1               5                   10                  15


Gln Asn His Ala Arg Glu Leu Val Gln Gly Leu Ser Leu Ser Glu Trp 
            20                  25                  30


Asp Gly Ile Val Thr Val Ser Gly Asp Gly Leu Leu His Glu Val Glu 
        35                  40                  45


Gln Glu His Pro Ala Pro Ser Pro Gly Pro Trp Gly Thr 
    50                  55                  60


<210>  9306
<211>  373
<212>  DNA
<213>  Homo sapiens

<400>  9306
agtgttggag gtgaggaggc ggggctggca gggctagtcg gggcatctgg aaatttccga     60

ccccacgctt cgggcgtttc cttatcaggt tcaccgctcc ctgatctcgc gctgcacttc    120

gtaggcgcag ccgctgcttg ggaagtccta cttaagagct gaaggtcagg ccaggacagt    180

gagacctgac tccttgctcc taccagccta ctatggctta agacccaggg ccagggtccc    240

gttgatgtaa cagagcagag gaccagcaga tgaatggaca ccttgaagca gaggagcagc    300

aggaccaggt aagggaccat ctaaaagcca agatcctcat actgtggaaa gacaaaatct    360

gaagcttttc ttt                                                       373


<210>  9307
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  9307

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Val Arg Asp 
1               5                   10                  15


His Leu Lys Ala Lys Ile Leu Ile Leu Trp Lys Asp Lys Ile 
            20                  25                  30


<210>  9308
<211>  776
<212>  DNA
<213>  Homo sapiens

<400>  9308
agtgttggag gtgaggaggc ggggctggca gggctagtcg gggcatctgg aaatttccga     60

ccccacgctt cgggcgtttc cttatcagag ctgaaggtca ggccaggaca gtgagacctg    120

actccttgct cctaccagcc tactatggct taagacccag ggccagggtc ccgttgatgt    180

aacagagcag aggaccagca gatgaatgga caccttgaag cagaggagca gcaggaccag    240

aggccagacc aggagctgac cgggagctgg ggccacgggc ctaggagcac cctggtcagg    300

gctaaggcca tggccccgcc cccaccgcca ctggctgcca gcaccccgct cctccatggc    360

gagtttggct cctacccagc ccgaggccca cgctttgccc tcacccttac atcgcaggcc    420

ctgcacatac agcggctgcg ccccaaacct gaagccaggc cccggggtgg cctggtcccg    480

ttggccgagg tctcaggctg ctgcaccctg cgaagccgca gcccctcaga ctcagcggcc    540

tacttctgca tctacaccta ccctcggggc cggcgcgggg cccggcgcag agccactcgc    600

accttccggg cagatggggc cgccacctac gaagagaacc gtgccgaggc ccagcgctgg    660

gccactgccc tcacctgtct gctccgagga ctgccactgc ccggggatgg gggtgaggtg    720

ctgggcagct gctctatcct ggagccacct tggtgtctct gcagaatttc ctccat        776


<210>  9309
<211>  190
<212>  PRT
<213>  Homo sapiens

<400>  9309

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser 
                165                 170                 175


Cys Ser Ile Leu Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser 
            180                 185                 190


<210>  9310
<211>  867
<212>  DNA
<213>  Homo sapiens

<400>  9310
agtgttggag gtgaggaggc ggggctggca gggctagtcg gggcatctgg aaatttccga     60

ccccacgctt cgggcgtttc cttatcaggt tcaccgctcc ctgatctcgc gctgcacttc    120

gtaggcgcag ccgctgcttg ggaagtccta cttaagagct gaaggtcagg ccaggacagt    180

gagacctgac tccttgctcc taccagccta ctatggctta agacccaggg ccagggtccc    240

gttgatgtaa cagagcagag gaccagcaga tgaatggaca ccttgaagca gaggagcagc    300

aggaccagag gccagaccag gagctgaccg ggagctgggg ccacgggcct aggagcaccc    360

tggtcagggc taaggccatg gccccgcccc caccgccact ggctgccagc accccgctcc    420

tccatggcga gtttggctcc tacccagccc gaggcccacg ctttgccctc acccttacat    480

cgcaggccct gcacatacag cggctgcgcc ccaaacctga agccaggccc cggggtggcc    540

tggtcccgtt ggccgaggtc tcaggctgct gcaccctgcg aagccgcagc ccctcagact    600

cagcggccta cttctgcatc tacacctacc ctcggggccg gcgcggggcc cggcgcagag    660

ccactcgcac cttccgggca gatggggccg ccacctacga agagaaccgt gccgaggccc    720

agcgctgggc cactgccctc acctgtctgc tccgaggact gccactgccc ggggatgggg    780

gtgaggtgct gggcagctgc tctatcctgg agccaccttg gtgtctctgc agaatttcct    840

ccataggcag ctgtgtcttt atttttc                                        867


<210>  9311
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  9311

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser 
                165                 170                 175


Cys Ser Ile Leu Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser Ser Ile 
            180                 185                 190


Gly Ser Cys Val Phe Ile 
        195


<210>  9312
<211>  1544
<212>  DNA
<213>  Homo sapiens

<400>  9312
agtgttggag gtgaggaggc ggggctggca gggctagtcg gggcatctgg aaatttccga     60

ccccacgctt cgggcgtttc cttatcaggt tcaccgctcc ctgatctcgc gctgcacttc    120

gtaggcgcag ccgctgcttg ggaagtccta cttaagagct gaaggtcagg ccaggacagt    180

gagacctgac tccttgctcc taccagcccc tgcccatagc ctgcctcgtg ccaagtcgga    240

gctgacccta accccagaag aacccctgcc catcctgtcc ctcaacggtg ggggcccaga    300

gctggctggg gactggggtg gggctgggga tgctccgctg tccccggacc cactgctgtc    360

ttcacctcct ggctctccca aggcagctct acactcaccc gtctccgaag gggcccccgt    420

aattccccca tcctctgggc tcccacttcc cacccctgat gcccgggtag gggcctccac    480

ctgcggcccg cccgaccacc tgctgcctcc gctgggcacc ccgctgcccc cagactgggt    540

gacgctggag ggggactttg tgctcatgtt ggccatctcg cccagccacc taggcgctga    600

cctggtggca gctccgcatg cgcgcttcga cgacggcctg gtgcacctgt gctgggtgcg    660

tagcggcatc tcgcgggctg cgctgctgcg ccttttcttg gccatggagc gtggtagcca    720

cttcagcctg ggctgtccgc agctgggcta cgccgcggcc cgtgccttcc gcctagagcc    780

gctcacacca cgcggcgtgc tcacagtgga cggggagcag gtggagtatg ggccgctaca    840

ggcacagatg caccctggca tcggtacact gctcactggg cctcctggct gcccggggcg    900

ggagccctga aactaaacaa gcttggtacc cgccgggggc ggggcctaca ttccaatggg    960

gcggagcctg agctaggggg tgtggcctgg ctgctagagt tgtggtggca ggggccctgg   1020

ccccgtctca ggattgcgct cgctttcatg ggaccagacg tgatgctgga aggtgggcgt   1080

cgtcacggtt aaagagaaat gggctcgtcc cgagggtagt gcctgatcaa tgagggcggg   1140

gcctggcgtc tgatctgggg ccgcccttac ggggcagggc tcagtcctga cgcttgccac   1200

ctgctcctac ccggccagga tggctgaggg cggagtctat tttacgcgtc gcccaatgac   1260

aggacctgga atgtactggc tggggtaggc ctcagtgagt cggccggtca gggcccgcag   1320

cctcgcccca tccactccgg tgcctccatt tagctggcca atcagcccag gaggggcagg   1380

ttccccgggg ccggcgctag gatttgcact aatgttcctc tccccgcggg tgggggcggg   1440

gaaattcata tcccctgttc gtctcatgcg cgtcctccgt ccccaatcta aaaagcaatt   1500

gaaaaggtct atgcaataaa ggcagtcgct tcattcctct caga                    1544


<210>  9313
<211>  114
<212>  PRT
<213>  Homo sapiens

<400>  9313

Met Leu Ala Ile Ser Pro Ser His Leu Gly Ala Asp Leu Val Ala Ala 
1               5                   10                  15


Pro His Ala Arg Phe Asp Asp Gly Leu Val His Leu Cys Trp Val Arg 
            20                  25                  30


Ser Gly Ile Ser Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala Met Glu 
        35                  40                  45


Arg Gly Ser His Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr Ala Ala 
    50                  55                  60


Ala Arg Ala Phe Arg Leu Glu Pro Leu Thr Pro Arg Gly Val Leu Thr 
65                  70                  75                  80


Val Asp Gly Glu Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln Met His 
                85                  90                  95


Pro Gly Ile Gly Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro Gly Arg 
            100                 105                 110


Glu Pro 



<210>  9314
<211>  2868
<212>  DNA
<213>  Homo sapiens

<400>  9314
agtgttggag gtgaggaggc ggggctggca gggctagtcg gggcatctgg aaatttccga     60

ccccacgctt cgggcgtttc cttatcaggt tcaccgctcc ctgatctcgc gctgcacttc    120

gtaggcgcag ccgctgcttg ggaagtccta cttaagagct gaaggtcagg ccaggacagt    180

gagacctgac tccttgctcc taccagccta ctatggctta agacccaggg ccagggtccc    240

gttgatgtaa cagagcagag gaccagcaga tgaatggaca ccttgaagca gaggagcagc    300

aggaccagag gccagaccag gagctgaccg ggagctgggg ccacgggcct aggagcaccc    360

tggtcagggc taaggccatg gccccgcccc caccgccact ggctgccagc accccgctcc    420

tccatggcga gtttggctcc tacccagccc gaggcccacg ctttgccctc acccttacat    480

cgcaggccct gcacatacag cggctgcgcc ccaaacctga agccaggccc cggggtggcc    540

tggtcccgtt ggccgaggtc tcaggctgct gcaccctgcg aagccgcagc ccctcagact    600

cagcggccta cttctgcatc tacacctacc ctcggggccg gcgcggggcc cggcgcagag    660

ccactcgcac cttccgggca gatggggccg ccacctacga agagaaccgt gccgaggccc    720

agcgctgggc cactgccctc acctgtctgc tccgaggact gccactgccc ggggatgggg    780

agatcacccc tgacctgcta cctcggccgc cccggttgct tctattggtc aatccctttg    840

ggggtcgggg cctggcctgg cagtggtgta agaaccacgt gcttcccatg atctctgaag    900

ctgggctgtc cttcaacctc atccagacag aacgacagaa ccacgcccgg gagctggtcc    960

aggggctgag cctgagtgag tgggatggca tcgtcacggt ctcgggagac gggctgctcc   1020

atgaggtgct gaacgggctc ctagatcgcc ctgactggga ggaagctgtg aagatgcctg   1080

tgggcatcct cccctgcggc tcgggcaacg cgctggccgg agcagtgaac cagcacgggg   1140

gatttgagcc agccctgggc ctcgacctgt tgctcaactg ctcactgttg ctgtgccggg   1200

gtggtggcca cccactggac ctgctctccg tgacgctggc ctcgggctcc cgctgtttct   1260

ccttcctgtc tgtggcctgg ggcttcgtgt cagatgtgga tatccagagc gagcgcttca   1320

gggccttggg cagtgcccgc ttcacactgg gcacggtgct gggcctcgcc acactgcaca   1380

cctaccgcgg acgcctctcc tacctccccg ccactgtgga acctgcctcg cccacccctg   1440

cccatagcct gcctcgtgcc aagtcggagc tgaccctaac cccagaccca gccccgccca   1500

tggcccactc acccctgcat cgttctgtgt ctgacctgcc tcttcccctg ccccagcctg   1560

ccctggcctc tcctggctcg ccagaacccc tgcccatcct gtccctcaac ggtgggggcc   1620

cagagctggc tggggactgg ggtggggctg gggatgctcc gctgtccccg gacccactgc   1680

tgtcttcacc tcctggctct cccaaggcag ctctacactc acccgtctcc gaaggggccc   1740

ccgtaattcc cccatcctct gggctcccac ttcccacccc tgatgcccgg gtaggggcct   1800

ccacctgcgg cccgcccgac cacctgctgc ctccgctggg caccccgctg cccccagact   1860

gggtgacgct ggagggggac tttgtgctca tgttggccat ctcgcccagc cacctaggcg   1920

ctgacctggt ggcagctccg catgcgcgct tcgacgacgg cctggtgcac ctgtgctggg   1980

tgcgtagcgg catctcgcgg gctgcgctgc tgcgcctttt cttggccatg gagcgtggta   2040

gccacttcag cctgggctgt ccgcagctgg gctacgccgc ggcccgtgcc ttccgcctag   2100

agccgctcac accacgcggc gtgctcacag tggacgggga gcaggtggag tatgggccgc   2160

tacaggcaca gatgcaccct ggcatcggta cactgctcac tgggcctcct ggctgcccgg   2220

ggcgggagcc ctgaaactaa acaagcttgg tacccgccgg gggcggggcc tacattccaa   2280

tggggcggag cctgagctag ggggtgtggc ctggctgcta gagttgtggt ggcaggggcc   2340

ctggccccgt ctcaggattg cgctcgcttt catgggacca gacgtgatgc tggaaggtgg   2400

gcgtcgtcac ggttaaagag aaatgggctc gtcccgaggg tagtgcctga tcaatgaggg   2460

cggggcctgg cgtctgatct ggggccgccc ttacggggca gggctcagtc ctgacgcttg   2520

ccacctgctc ctacccggcc aggatggctg agggcggagt ctattttacg cgtcgcccaa   2580

tgacaggacc tggaatgtac tggctggggt aggcctcagt gagtcggccg gtcagggccc   2640

gcagcctcgc cccatccact ccggtgcctc catttagctg gccaatcagc ccaggagggg   2700

caggttcccc ggggccggcg ctaggatttg cactaatgtt cctctccccg cgggtggggg   2760

cggggaaatt catatcccct gttcgtctca tgcgcgtcct ccgtccccaa tctaaaaagc   2820

aattgaaaag gtctatgcaa taaaggcagt cgcttcattc ctctcaga                2868


<210>  9315
<211>  654
<212>  PRT
<213>  Homo sapiens

<400>  9315

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Glu Ile Thr Pro Asp Leu 
                165                 170                 175


Leu Pro Arg Pro Pro Arg Leu Leu Leu Leu Val Asn Pro Phe Gly Gly 
            180                 185                 190


Arg Gly Leu Ala Trp Gln Trp Cys Lys Asn His Val Leu Pro Met Ile 
        195                 200                 205


Ser Glu Ala Gly Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg Gln Asn 
    210                 215                 220


His Ala Arg Glu Leu Val Gln Gly Leu Ser Leu Ser Glu Trp Asp Gly 
225                 230                 235                 240


Ile Val Thr Val Ser Gly Asp Gly Leu Leu His Glu Val Leu Asn Gly 
                245                 250                 255


Leu Leu Asp Arg Pro Asp Trp Glu Glu Ala Val Lys Met Pro Val Gly 
            260                 265                 270


Ile Leu Pro Cys Gly Ser Gly Asn Ala Leu Ala Gly Ala Val Asn Gln 
        275                 280                 285


His Gly Gly Phe Glu Pro Ala Leu Gly Leu Asp Leu Leu Leu Asn Cys 
    290                 295                 300


Ser Leu Leu Leu Cys Arg Gly Gly Gly His Pro Leu Asp Leu Leu Ser 
305                 310                 315                 320


Val Thr Leu Ala Ser Gly Ser Arg Cys Phe Ser Phe Leu Ser Val Ala 
                325                 330                 335


Trp Gly Phe Val Ser Asp Val Asp Ile Gln Ser Glu Arg Phe Arg Ala 
            340                 345                 350


Leu Gly Ser Ala Arg Phe Thr Leu Gly Thr Val Leu Gly Leu Ala Thr 
        355                 360                 365


Leu His Thr Tyr Arg Gly Arg Leu Ser Tyr Leu Pro Ala Thr Val Glu 
    370                 375                 380


Pro Ala Ser Pro Thr Pro Ala His Ser Leu Pro Arg Ala Lys Ser Glu 
385                 390                 395                 400


Leu Thr Leu Thr Pro Asp Pro Ala Pro Pro Met Ala His Ser Pro Leu 
                405                 410                 415


His Arg Ser Val Ser Asp Leu Pro Leu Pro Leu Pro Gln Pro Ala Leu 
            420                 425                 430


Ala Ser Pro Gly Ser Pro Glu Pro Leu Pro Ile Leu Ser Leu Asn Gly 
        435                 440                 445


Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly Gly Ala Gly Asp Ala Pro 
    450                 455                 460


Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro Pro Gly Ser Pro Lys Ala 
465                 470                 475                 480


Ala Leu His Ser Pro Val Ser Glu Gly Ala Pro Val Ile Pro Pro Ser 
                485                 490                 495


Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala Arg Val Gly Ala Ser Thr 
            500                 505                 510


Cys Gly Pro Pro Asp His Leu Leu Pro Pro Leu Gly Thr Pro Leu Pro 
        515                 520                 525


Pro Asp Trp Val Thr Leu Glu Gly Asp Phe Val Leu Met Leu Ala Ile 
    530                 535                 540


Ser Pro Ser His Leu Gly Ala Asp Leu Val Ala Ala Pro His Ala Arg 
545                 550                 555                 560


Phe Asp Asp Gly Leu Val His Leu Cys Trp Val Arg Ser Gly Ile Ser 
                565                 570                 575


Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala Met Glu Arg Gly Ser His 
            580                 585                 590


Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr Ala Ala Ala Arg Ala Phe 
        595                 600                 605


Arg Leu Glu Pro Leu Thr Pro Arg Gly Val Leu Thr Val Asp Gly Glu 
    610                 615                 620


Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln Met His Pro Gly Ile Gly 
625                 630                 635                 640


Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro Gly Arg Glu Pro 
                645                 650


<210>  9316
<211>  1638
<212>  DNA
<213>  Homo sapiens

<400>  9316
atcaggttca ccgctccctg atctcgcgct gcacttcgta ggcgcagccg ctgcttggga     60

agtcctactt aagagctgaa ggtcaggcca ggacagtgag acctgactcc ttgctcctac    120

cagcctacta tggcttaaga cccagggcca gggtcccgtt gatgtaacag agcagaggac    180

cagcagatga atggacacct tgaagcagag gagcagcagg accagaggcc agaccaggag    240

ctgaccggga gctggggcca cgggcctagg agcaccctgg tcagggctaa ggccatggcc    300

ccgcccccac cgccactggc tgccagcacc ccgctcctcc atggcgagtt tggctcctac    360

ccagcccgag gcccacgctt tgccctcacc cttacatcgc aggccctgca catacagcgg    420

ctgcgcccca aacctgaagc caggccccgg ggtggcctgg tcccgttggc cgaggtctca    480

ggctgctgca ccctgcgaag ccgcagcccc tcagactcag cggcctactt ctgcatctac    540

acctaccccc tgatgcccgg gtaggggcct ccacctgcgg cccgcccgac cacctgctgc    600

ctccgctggg caccccgctg cccccagact gggtgacgct ggagggggac tttgtgctca    660

tgttggccat ctcgcccagc cacctaggcg ctgacctggt ggcagctccg catgcgcgct    720

tcgacgacgg cctggtgcac ctgtgctggg tgcgtagcgg catctcgcgg gctgcgctgc    780

tgcgcctttt cttggccatg gagcgtggta gccacttcag cctgggctgt ccgcagctgg    840

gctacgccgc ggcccgtgcc ttccgcctag agccgctcac accacgcggc gtgctcacag    900

tggacgggga gcaggtggag tatgggccgc tacaggcaca gatgcaccct ggcatcggta    960

cactgctcac tgggcctcct ggctgcccgg ggcgggagcc ctgaaactaa acaagcttgg   1020

tacccgccgg gggcggggcc tacattccaa tggggcggag cctgagctag ggggtgtggc   1080

ctggctgcta gagttgtggt ggcaggggcc ctggccccgt ctcaggattg cgctcgcttt   1140

catgggacca gacgtgatgc tggaaggtgg gcgtcgtcac ggttaaagag aaatgggctc   1200

gtcccgaggg tagtgcctga tcaatgaggg cggggcctgg cgtctgatct ggggccgccc   1260

ttacggggca gggctcagtc ctgacgcttg ccacctgctc ctacccggcc aggatggctg   1320

agggcggagt ctattttacg cgtcgcccaa tgacaggacc tggaatgtac tggctggggt   1380

aggcctcagt gagtcggccg gtcagggccc gcagcctcgc cccatccact ccggtgcctc   1440

catttagctg gccaatcagc ccaggagggg caggttcccc ggggccggcg ctaggatttg   1500

cactaatgtt cctctccccg cgggtggggg cggggaaatt catatcccct gttcgtctca   1560

tgcgcgtcct ccgtccccaa tctaaaaagc aattgaaaag gtctatgcaa taaaggcagt   1620

cgcttcattc ctctcaga                                                 1638


<210>  9317
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  9317

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Leu Met Pro Gly 
        115                 120                 125


<210>  9318
<211>  856
<212>  DNA
<213>  Homo sapiens

<400>  9318
gatggccctt ccctgaccta gaaagaggga gacagagttt cataggggag gcaaaatgga     60

gactccgtgg cttgggggtg gggggaatgg aggcccaaag ggtaggaagg agacctagaa    120

agaggggtga gatggagacc cagggagaag tagtggcaaa gaaagatgag ctgaaggtca    180

ggccaggaca gtgagacctg actccttgct cctaccagcc tactatggct taagacccag    240

ggccagggtc ccgttgatgt aacagagcag aggaccagca gatgaatgga caccttgaag    300

cagaggagca gcaggaccag aggccagacc aggagctgac cgggagctgg ggccacgggc    360

ctaggagcac cctggtcagg gctaaggcca tggccccgcc cccaccgcca ctggctgcca    420

gcaccccgct cctccatggc gagtttggct cctacccagc ccgaggccca cgctttgccc    480

tcacccttac atcgcaggcc ctgcacatac agcggctgcg ccccaaacct gaagccaggc    540

cccggggtgg cctggtcccg ttggccgagg tctcaggctg ctgcaccctg cgaagccgca    600

gcccctcaga ctcagcggcc tacttctgca tctacaccta ccctcggggc cggcgcgggg    660

cccggcgcag agccactcgc accttccggg cagatggggc cgccacctac gaagagaacc    720

gtgccgaggc ccagcgctgg gccactgccc tcacctgtct gctccgagga ctgccactgc    780

ccggggatgg gggtgaggtg ctgggcagct gctctatcct ggagccacct tggtgtctct    840

gcagaatttc ctccat                                                    856


<210>  9319
<211>  190
<212>  PRT
<213>  Homo sapiens

<400>  9319

Met Asn Gly His Leu Glu Ala Glu Glu Gln Gln Asp Gln Arg Pro Asp 
1               5                   10                  15


Gln Glu Leu Thr Gly Ser Trp Gly His Gly Pro Arg Ser Thr Leu Val 
            20                  25                  30


Arg Ala Lys Ala Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr 
        35                  40                  45


Pro Leu Leu His Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg 
    50                  55                  60


Phe Ala Leu Thr Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg 
65                  70                  75                  80


Pro Lys Pro Glu Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu 
                85                  90                  95


Val Ser Gly Cys Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala 
            100                 105                 110


Ala Tyr Phe Cys Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg 
        115                 120                 125


Arg Arg Ala Thr Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu 
    130                 135                 140


Glu Asn Arg Ala Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu 
145                 150                 155                 160


Leu Arg Gly Leu Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser 
                165                 170                 175


Cys Ser Ile Leu Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser 
            180                 185                 190


<210>  9320
<211>  961
<212>  DNA
<213>  Homo sapiens

<400>  9320
atctctgggc ctttgttacg cgtgttagag tctctgtctt tgcagctaaa gacctcctcc     60

ctcacgcccc ttttcttttg tgaattcaat ggatgagaca ggcccactct cccttaacaa    120

agatggcgac aacggcgctg tctatggggc cgcgacgtcg tctccgctgc gcgtcggccc    180

tcacccacga tggcggccag tctcccgaag cgcgaggccc cgcccagctc tcggcctctc    240

ccgcggccgg tccctgcacc aagctcgcga gctgactggc tccacccccc gcgccctcgt    300

attggtgcgg cccaggccgg ctgcacggcc attggctgag cggatgcaca ccctcccccc    360

acccctaggt ctgatggggg ctgttggtgc tgacttgcgg gaccgcctgg aggaggaccc    420

ggcgtaggcc agaccaggag ctgaccggga gctggggcca cgggcctagg agcaccctgg    480

tcagggctaa ggccatggcc ccgcccccac cgccactggc tgccagcacc ccgctcctcc    540

atggcgagtt tggctcctac ccagcccgag gcccacgctt tgccctcacc cttacatcgc    600

aggccctgca catacagcgg ctgcgcccca aacctgaagc caggccccgg ggtggcctgg    660

tcccgttggc cgaggtctca ggctgctgca ccctgcgaag ccgcagcccc tcagactcag    720

cggcctactt ctgcatctac acctaccctc ggggccggcg cggggcccgg cgcagagcca    780

ctcgcacctt ccgggcagat ggggccgcca cctacgaaga gaaccgtgcc gaggcccagc    840

gctgggccac tgccctcacc tgtctgctcc gaggactgcc actgcccggg gatgggggtg    900

aggtgctggg cagctgctct atcctggagc caccttggtg tctctgcaga atttcctcca    960

t                                                                    961


<210>  9321
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  9321

Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr Pro Leu Leu His 
1               5                   10                  15


Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg Phe Ala Leu Thr 
            20                  25                  30


Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg Pro Lys Pro Glu 
        35                  40                  45


Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu Val Ser Gly Cys 
    50                  55                  60


Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala Ala Tyr Phe Cys 
65                  70                  75                  80


Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg Arg Arg Ala Thr 
                85                  90                  95


Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu Glu Asn Arg Ala 
            100                 105                 110


Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu Leu Arg Gly Leu 
        115                 120                 125


Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser Cys Ser Ile Leu 
    130                 135                 140


Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser 
145                 150


<210>  9322
<211>  1211
<212>  DNA
<213>  Homo sapiens

<400>  9322
attggctgag cggatgcaca ccctcccccc acccctaggt ctgatggggg ctgttggtgc     60

tgacttgcgg gaccgcctgg aggaggaccc ggcgtaggcc agaccaggag ctgaccggga    120

gctggggcca cgggcctagg agcaccctgg tcagggctaa ggccatggcc ccgcccccac    180

cgccactggc tgccagcacc ccgctcctcc atggcgagtt tggctcctac ccagcccgag    240

gcccacgctt tgccctcacc cttacatcgc aggccctgca catacagcgg ctgcgcccca    300

aacctgaagc caggccccgg ggtggcctgg tcccgttggc cgaggtctca ggctgctgca    360

ccctgcgaag ccgcagcccc tcagactcag cggcctactt ctgcatctac acctaccctc    420

ggggccggcg cggggcccgg cgcagagcca ctcgcacctt ccgggcagat ggggccgcca    480

cctacgaaga gaaccgtgcc gaggcccagc gctgggccac tgccctcacc tgtctgctcc    540

gaggactgcc actgcccggg gatggggaga tcacccctga cctgctacct cggccgcccc    600

ggttgcttct attggtcaat ccctttgggg gtcggggcct ggcctggcag tggtgtaaga    660

accacgtgct tcccatgatc tctgaagctg ggctgtcctt caacctcatc cagacagaac    720

gacagaacca cgcccgggag ctggtccagg ggctgagcct gagtgagtgg gatggcatcg    780

tcacggtctc gggagacggg ctgctccatg aggtgctgaa cgggctccta gatcgccctg    840

actgggagga agctgtgaag atgcctgtgg gcatcctccc ctgcggctcg ggcaacgcgc    900

tggccggagc agtgaaccag cacgggggcc cgcgggagga ctcagactcc agcacttcca    960

gcagcgcctg ccctctatgg acgacagccc ggagctgccc acgggctgca gccagtatgc   1020

cagggagctg ccctcttctt ccacaacagc tggctctggg gttctcaaga tttattcagg   1080

atcgtgttaa cggaggcggt gggaggatag ggtccctgac gtgccgggga cacacacaga   1140

gaaccctccc cgcccccgca agggaggggg gaggctcgct ttttcttaaa aatataaatg   1200

tatttatctg c                                                        1211


<210>  9323
<211>  348
<212>  PRT
<213>  Homo sapiens

<400>  9323

Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr Pro Leu Leu His 
1               5                   10                  15


Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg Phe Ala Leu Thr 
            20                  25                  30


Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg Pro Lys Pro Glu 
        35                  40                  45


Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu Val Ser Gly Cys 
    50                  55                  60


Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala Ala Tyr Phe Cys 
65                  70                  75                  80


Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg Arg Arg Ala Thr 
                85                  90                  95


Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu Glu Asn Arg Ala 
            100                 105                 110


Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu Leu Arg Gly Leu 
        115                 120                 125


Pro Leu Pro Gly Asp Gly Glu Ile Thr Pro Asp Leu Leu Pro Arg Pro 
    130                 135                 140


Pro Arg Leu Leu Leu Leu Val Asn Pro Phe Gly Gly Arg Gly Leu Ala 
145                 150                 155                 160


Trp Gln Trp Cys Lys Asn His Val Leu Pro Met Ile Ser Glu Ala Gly 
                165                 170                 175


Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg Gln Asn His Ala Arg Glu 
            180                 185                 190


Leu Val Gln Gly Leu Ser Leu Ser Glu Trp Asp Gly Ile Val Thr Val 
        195                 200                 205


Ser Gly Asp Gly Leu Leu His Glu Val Leu Asn Gly Leu Leu Asp Arg 
    210                 215                 220


Pro Asp Trp Glu Glu Ala Val Lys Met Pro Val Gly Ile Leu Pro Cys 
225                 230                 235                 240


Gly Ser Gly Asn Ala Leu Ala Gly Ala Val Asn Gln His Gly Gly Pro 
                245                 250                 255


Arg Glu Asp Ser Asp Ser Ser Thr Ser Ser Ser Ala Cys Pro Leu Trp 
            260                 265                 270


Thr Thr Ala Arg Ser Cys Pro Arg Ala Ala Ala Ser Met Pro Gly Ser 
        275                 280                 285


Cys Pro Leu Leu Pro Gln Gln Leu Ala Leu Gly Phe Ser Arg Phe Ile 
    290                 295                 300


Gln Asp Arg Val Asn Gly Gly Gly Gly Arg Ile Gly Ser Leu Thr Cys 
305                 310                 315                 320


Arg Gly His Thr Gln Arg Thr Leu Pro Ala Pro Ala Arg Glu Gly Gly 
                325                 330                 335


Gly Ser Leu Phe Leu Lys Asn Ile Asn Val Phe Ile 
            340                 345


<210>  9324
<211>  1022
<212>  DNA
<213>  Homo sapiens

<400>  9324
ctaggtctga tgggggctgt tggtgctgac ttgcgggacc gcctggagga ggacccggcg     60

tgtgaggagg gtgcgggggt cggggcaggg accggagtct aggggactga gggaccaaga    120

ggaacagaga ctcaggcccg ggactggggc accggggtgg gagatggaaa tggaaaacct    180

gggccaggac tgaacccagc caggcctggg actgggttct ggaaataaga gtgcggatgg    240

cggtttgggg gcccagggcc agacacgcag gcctatggat tggggaccaa tggatggaga    300

cccaggtcca ggtctcgggg acccagggac agagacccag gcccaagact ggaggacatc    360

tagggctctg tgcttgaacc tgatttgagg ttcccataat ggggccaggg caggtttggg    420

ggtgaagcag acgtcctgga cccgagagag ccgctgggga taggggggca gatgtagttc    480

ctaaggaggc cagaccagga gctgaccggg agctggggcc acgggcctag gagcaccctg    540

gtcagggcta aggccatggc cccgccccca ccgccactgg ctgccagcac cccgctcctc    600

catggcgagt ttggctccta cccagcccga ggcccacgct ttgccctcac ccttacatcg    660

caggccctgc acatacagcg gctgcgcccc aaacctgaag ccaggccccg gggtggcctg    720

gtcccgttgg ccgaggtctc aggctgctgc accctgcgaa gccgcagccc ctcagactca    780

gcggcctact tctgcatcta cacctaccct cggggccggc gcggggcccg gcgcagagcc    840

actcgcacct tccgggcaga tggggccgcc acctacgaag agaaccgtgc cgaggcccag    900

cgctgggcca ctgccctcac ctgtctgctc cgaggactgc cactgcccgg ggatgggggt    960

gaggtgctgg gcagctgctc tatcctggag ccaccttggt gtctctgcag aatttcctcc   1020

at                                                                  1022


<210>  9325
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  9325

Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr Pro Leu Leu His 
1               5                   10                  15


Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg Phe Ala Leu Thr 
            20                  25                  30


Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg Pro Lys Pro Glu 
        35                  40                  45


Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu Val Ser Gly Cys 
    50                  55                  60


Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala Ala Tyr Phe Cys 
65                  70                  75                  80


Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg Arg Arg Ala Thr 
                85                  90                  95


Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu Glu Asn Arg Ala 
            100                 105                 110


Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu Leu Arg Gly Leu 
        115                 120                 125


Pro Leu Pro Gly Asp Gly Gly Glu Val Leu Gly Ser Cys Ser Ile Leu 
    130                 135                 140


Glu Pro Pro Trp Cys Leu Cys Arg Ile Ser 
145                 150


<210>  9326
<211>  2685
<212>  DNA
<213>  Homo sapiens

<400>  9326
ggggaacaaa ggtgagcgaa aggaggaggc agaatccggg cagagggcag ggagagggcc     60

tgtggggaag ggacctcagt cctgctccca cccgctccct ggagagcagg cggccagaca    120

cccagaggcc agaccaggag ctgaccggga gctggggcca cgggcctagg agcaccctgg    180

tcagggctaa ggccatggcc ccgcccccac cgccactggc tgccagcacc ccgctcctcc    240

atggcgagtt tggctcctac ccagcccgag gcccacgctt tgccctcacc cttacatcgc    300

aggccctgca catacagcgg ctgcgcccca aacctgaagc caggccccgg ggtggcctgg    360

tcccgttggc cgaggtctca ggctgctgca ccctgcgaag ccgcagcccc tcagactcag    420

cggcctactt ctgcatctac acctaccctc ggggccggcg cggggcccgg cgcagagcca    480

ctcgcacctt ccgggcagat ggggccgcca cctacgaaga gaaccgtgcc gaggcccagc    540

gctgggccac tgccctcacc tgtctgctcc gaggactgcc actgcccggg gatggggaga    600

tcacccctga cctgctacct cggccgcccc ggttgcttct attggtcaat ccctttgggg    660

gtcggggcct ggcctggcag tggtgtaaga accacgtgct tcccatgatc tctgaagctg    720

ggctgtcctt caacctcatc cagacagaac gacagaacca cgcccgggag ctggtccagg    780

ggctgagcct gagtgagtgg gatggcatcg tcacggtctc gggagacggg ctgctccatg    840

aggtgctgaa cgggctccta gatcgccctg actgggagga agctgtgaag atgcctgtgg    900

gcatcctccc ctgcggctcg ggcaacgcgc tggccggagc agtgaaccag cacgggggat    960

ttgagccagc cctgggcctc gacctgttgc tcaactgctc actgttgctg tgccggggtg   1020

gtggccaccc actggacctg ctctccgtga cgctggcctc gggctcccgc tgtttctcct   1080

tcctgtctgt ggcctggggc ttcgtgtcag atgtggatat ccagagcgag cgcttcaggg   1140

ccttgggcag tgcccgcttc acactgggca cggtgctggg cctcgccaca ctgcacacct   1200

accgcggacg cctctcctac ctccccgcca ctgtggaacc tgcctcgccc acccctgccc   1260

atagcctgcc tcgtgccaag tcggagctga ccctaacccc agacccagcc ccgcccatgg   1320

cccactcacc cctgcatcgt tctgtgtctg acctgcctct tcccctgccc cagcctgccc   1380

tggcctctcc tggctcgcca gaacccctgc ccatcctgtc cctcaacggt gggggcccag   1440

agctggctgg ggactggggt ggggctgggg atgctccgct gtccccggac ccactgctgt   1500

cttcacctcc tggctctccc aaggcagctc tacactcacc cgtctccgaa ggggcccccg   1560

taattccccc atcctctggg ctcccacttc ccacccctga tgcccgggta ggggcctcca   1620

cctgcggccc gcccgaccac ctgctgcctc cgctgggcac cccgctgccc ccagactggg   1680

tgacgctgga gggggacttt gtgctcatgt tggccatctc gcccagccac ctaggcgctg   1740

acctggtggc agctccgcat gcgcgcttcg acgacggcct ggtgcacctg tgctgggtgc   1800

gtagcggcat ctcgcgggct gcgctgctgc gccttttctt ggccatggag cgtggtagcc   1860

acttcagcct gggctgtccg cagctgggct acgccgcggc ccgtgccttc cgcctagagc   1920

cgctcacacc acgcggcgtg ctcacagtgg acggggagca ggtggagtat gggccgctac   1980

aggcacagat gcaccctggc atcggtacac tgctcactgg gcctcctggc tgcccggggc   2040

gggagccctg aaactaaaca agcttggtac ccgccggggg cggggcctac attccaatgg   2100

ggcggagcct gagctagggg gtgtggcctg gctgctagag ttgtggtggc aggggccctg   2160

gccccgtctc aggattgcgc tcgctttcat gggaccagac gtgatgctgg aaggtgggcg   2220

tcgtcacggt taaagagaaa tgggctcgtc ccgagggtag tgcctgatca atgagggcgg   2280

ggcctggcgt ctgatctggg gccgccctta cggggcaggg ctcagtcctg acgcttgcca   2340

cctgctccta cccggccagg atggctgagg gcggagtcta ttttacgcgt cgcccaatga   2400

caggacctgg aatgtactgg ctggggtagg cctcagtgag tcggccggtc agggcccgca   2460

gcctcgcccc atccactccg gtgcctccat ttagctggcc aatcagccca ggaggggcag   2520

gttccccggg gccggcgcta ggatttgcac taatgttcct ctccccgcgg gtgggggcgg   2580

ggaaattcat atcccctgtt cgtctcatgc gcgtcctccg tccccaatct aaaaagcaat   2640

tgaaaaggtc tatgcaataa aggcagtcgc ttcattcctc tcaga                   2685


<210>  9327
<211>  618
<212>  PRT
<213>  Homo sapiens

<400>  9327

Met Ala Pro Pro Pro Pro Pro Leu Ala Ala Ser Thr Pro Leu Leu His 
1               5                   10                  15


Gly Glu Phe Gly Ser Tyr Pro Ala Arg Gly Pro Arg Phe Ala Leu Thr 
            20                  25                  30


Leu Thr Ser Gln Ala Leu His Ile Gln Arg Leu Arg Pro Lys Pro Glu 
        35                  40                  45


Ala Arg Pro Arg Gly Gly Leu Val Pro Leu Ala Glu Val Ser Gly Cys 
    50                  55                  60


Cys Thr Leu Arg Ser Arg Ser Pro Ser Asp Ser Ala Ala Tyr Phe Cys 
65                  70                  75                  80


Ile Tyr Thr Tyr Pro Arg Gly Arg Arg Gly Ala Arg Arg Arg Ala Thr 
                85                  90                  95


Arg Thr Phe Arg Ala Asp Gly Ala Ala Thr Tyr Glu Glu Asn Arg Ala 
            100                 105                 110


Glu Ala Gln Arg Trp Ala Thr Ala Leu Thr Cys Leu Leu Arg Gly Leu 
        115                 120                 125


Pro Leu Pro Gly Asp Gly Glu Ile Thr Pro Asp Leu Leu Pro Arg Pro 
    130                 135                 140


Pro Arg Leu Leu Leu Leu Val Asn Pro Phe Gly Gly Arg Gly Leu Ala 
145                 150                 155                 160


Trp Gln Trp Cys Lys Asn His Val Leu Pro Met Ile Ser Glu Ala Gly 
                165                 170                 175


Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg Gln Asn His Ala Arg Glu 
            180                 185                 190


Leu Val Gln Gly Leu Ser Leu Ser Glu Trp Asp Gly Ile Val Thr Val 
        195                 200                 205


Ser Gly Asp Gly Leu Leu His Glu Val Leu Asn Gly Leu Leu Asp Arg 
    210                 215                 220


Pro Asp Trp Glu Glu Ala Val Lys Met Pro Val Gly Ile Leu Pro Cys 
225                 230                 235                 240


Gly Ser Gly Asn Ala Leu Ala Gly Ala Val Asn Gln His Gly Gly Phe 
                245                 250                 255


Glu Pro Ala Leu Gly Leu Asp Leu Leu Leu Asn Cys Ser Leu Leu Leu 
            260                 265                 270


Cys Arg Gly Gly Gly His Pro Leu Asp Leu Leu Ser Val Thr Leu Ala 
        275                 280                 285


Ser Gly Ser Arg Cys Phe Ser Phe Leu Ser Val Ala Trp Gly Phe Val 
    290                 295                 300


Ser Asp Val Asp Ile Gln Ser Glu Arg Phe Arg Ala Leu Gly Ser Ala 
305                 310                 315                 320


Arg Phe Thr Leu Gly Thr Val Leu Gly Leu Ala Thr Leu His Thr Tyr 
                325                 330                 335


Arg Gly Arg Leu Ser Tyr Leu Pro Ala Thr Val Glu Pro Ala Ser Pro 
            340                 345                 350


Thr Pro Ala His Ser Leu Pro Arg Ala Lys Ser Glu Leu Thr Leu Thr 
        355                 360                 365


Pro Asp Pro Ala Pro Pro Met Ala His Ser Pro Leu His Arg Ser Val 
    370                 375                 380


Ser Asp Leu Pro Leu Pro Leu Pro Gln Pro Ala Leu Ala Ser Pro Gly 
385                 390                 395                 400


Ser Pro Glu Pro Leu Pro Ile Leu Ser Leu Asn Gly Gly Gly Pro Glu 
                405                 410                 415


Leu Ala Gly Asp Trp Gly Gly Ala Gly Asp Ala Pro Leu Ser Pro Asp 
            420                 425                 430


Pro Leu Leu Ser Ser Pro Pro Gly Ser Pro Lys Ala Ala Leu His Ser 
        435                 440                 445


Pro Val Ser Glu Gly Ala Pro Val Ile Pro Pro Ser Ser Gly Leu Pro 
    450                 455                 460


Leu Pro Thr Pro Asp Ala Arg Val Gly Ala Ser Thr Cys Gly Pro Pro 
465                 470                 475                 480


Asp His Leu Leu Pro Pro Leu Gly Thr Pro Leu Pro Pro Asp Trp Val 
                485                 490                 495


Thr Leu Glu Gly Asp Phe Val Leu Met Leu Ala Ile Ser Pro Ser His 
            500                 505                 510


Leu Gly Ala Asp Leu Val Ala Ala Pro His Ala Arg Phe Asp Asp Gly 
        515                 520                 525


Leu Val His Leu Cys Trp Val Arg Ser Gly Ile Ser Arg Ala Ala Leu 
    530                 535                 540


Leu Arg Leu Phe Leu Ala Met Glu Arg Gly Ser His Phe Ser Leu Gly 
545                 550                 555                 560


Cys Pro Gln Leu Gly Tyr Ala Ala Ala Arg Ala Phe Arg Leu Glu Pro 
                565                 570                 575


Leu Thr Pro Arg Gly Val Leu Thr Val Asp Gly Glu Gln Val Glu Tyr 
            580                 585                 590


Gly Pro Leu Gln Ala Gln Met His Pro Gly Ile Gly Thr Leu Leu Thr 
        595                 600                 605


Gly Pro Pro Gly Cys Pro Gly Arg Glu Pro 
    610                 615


<210>  9328
<211>  2576
<212>  DNA
<213>  Homo sapiens

<400>  9328
tatgtttctg tctcctatcc tcttcccctt tgcatgggtc ttgaccacag gtgagtcacc     60

cagggtggtg agagcagcag cctgagacag gaccaggtac cacccagagt gatgggtgcc    120

aacagaggtc tagggcttcc ctggagttca gaggtggcat ctaatcctgc ctggggcccc    180

taagggctgg aagtaaccta atcctgggta ataggtgttt ggggtgagga aagtgggaac    240

cacagctctg aactacagct cctcccacac atggggacaa agggcatttg gtttcacacc    300

taagccctgc ctttgtctca gcagctagga gttggggcag ggctgcatac ctaggcctgg    360

ccacatgaga gccagcaggt cccaggggcc agccctccac caattccgtt gggggctgat    420

gaagggactg tttccaaggt ggggggcctg ggtcactggc ctctgcagac cctaacctct    480

ctccacagag atcacccctg acctgctacc tcggccgccc cggttgcttc tattggtcaa    540

tccctttggg ggtcggggcc tggcctggca gtggtgtaag aaccacgtgc ttcccatgat    600

ctctgaagct gggctgtcct tcaacctcat ccagacagaa cgacagaacc acgcccggga    660

gctggtccag gggctgagcc tgagtgagtg ggatggcatc gtcacggtct cgggagacgg    720

gctgctccat gaggtgctga acgggctcct agatcgccct gactgggagg aagctgtgaa    780

gatgcctgtg ggcatcctcc cctgcggctc gggcaacgcg ctggccggag cagtgaacca    840

gcacggggga tttgagccag ccctgggcct cgacctgttg ctcaactgct cactgttgct    900

gtgccggggt ggtggccacc cactggacct gctctccgtg acgctggcct cgggctcccg    960

ctgtttctcc ttcctgtctg tggcctgggg cttcgtgtca gatgtggata tccagagcga   1020

gcgcttcagg gccttgggca gtgcccgctt cacactgggc acggtgctgg gcctcgccac   1080

actgcacacc taccgcggac gcctctccta cctccccgcc actgtggaac ctgcctcgcc   1140

cacccctgcc catagcctgc ctcgtgccaa gtcggagctg accctaaccc cagacccagc   1200

cccgcccatg gcccactcac ccctgcatcg ttctgtgtct gacctgcctc ttcccctgcc   1260

ccagcctgcc ctggcctctc ctggctcgcc agaacccctg cccatcctgt ccctcaacgg   1320

tgggggccca gagctggctg gggactgggg tggggctggg gatgctccgc tgtccccgga   1380

cccactgctg tcttcacctc ctggctctcc caaggcagct ctacactcac ccgtctccga   1440

aggggccccc gtaattcccc catcctctgg gctcccactt cccacccctg atgcccgggt   1500

aggggcctcc acctgcggcc cgcccgacca cctgctgcct ccgctgggca ccccgctgcc   1560

cccagactgg gtgacgctgg agggggactt tgtgctcatg ttggccatct cgcccagcca   1620

cctaggcgct gacctggtgg cagctccgca tgcgcgcttc gacgacggcc tggtgcacct   1680

gtgctgggtg cgtagcggca tctcgcgggc tgcgctgctg cgccttttct tggccatgga   1740

gcgtggtagc cacttcagcc tgggctgtcc gcagctgggc tacgccgcgg cccgtgcctt   1800

ccgcctagag ccgctcacac cacgcggcgt gctcacagtg gacggggagc aggtggagta   1860

tgggccgcta caggcacaga tgcaccctgg catcggtaca ctgctcactg ggcctcctgg   1920

ctgcccgggg cgggagccct gaaactaaac aagcttggta cccgccgggg gcggggccta   1980

cattccaatg gggcggagcc tgagctaggg ggtgtggcct ggctgctaga gttgtggtgg   2040

caggggccct ggccccgtct caggattgcg ctcgctttca tgggaccaga cgtgatgctg   2100

gaaggtgggc gtcgtcacgg ttaaagagaa atgggctcgt cccgagggta gtgcctgatc   2160

aatgagggcg gggcctggcg tctgatctgg ggccgccctt acggggcagg gctcagtcct   2220

gacgcttgcc acctgctcct acccggccag gatggctgag ggcggagtct attttacgcg   2280

tcgcccaatg acaggacctg gaatgtactg gctggggtag gcctcagtga gtcggccggt   2340

cagggcccgc agcctcgccc catccactcc ggtgcctcca tttagctggc caatcagccc   2400

aggaggggca ggttccccgg ggccggcgct aggatttgca ctaatgttcc tctccccgcg   2460

ggtgggggcg gggaaattca tatcccctgt tcgtctcatg cgcgtcctcc gtccccaatc   2520

taaaaagcaa ttgaaaaggt ctatgcaata aaggcagtcg cttcattcct ctcaga       2576


<210>  9329
<211>  448
<212>  PRT
<213>  Homo sapiens

<400>  9329

Met Ile Ser Glu Ala Gly Leu Ser Phe Asn Leu Ile Gln Thr Glu Arg 
1               5                   10                  15


Gln Asn His Ala Arg Glu Leu Val Gln Gly Leu Ser Leu Ser Glu Trp 
            20                  25                  30


Asp Gly Ile Val Thr Val Ser Gly Asp Gly Leu Leu His Glu Val Leu 
        35                  40                  45


Asn Gly Leu Leu Asp Arg Pro Asp Trp Glu Glu Ala Val Lys Met Pro 
    50                  55                  60


Val Gly Ile Leu Pro Cys Gly Ser Gly Asn Ala Leu Ala Gly Ala Val 
65                  70                  75                  80


Asn Gln His Gly Gly Phe Glu Pro Ala Leu Gly Leu Asp Leu Leu Leu 
                85                  90                  95


Asn Cys Ser Leu Leu Leu Cys Arg Gly Gly Gly His Pro Leu Asp Leu 
            100                 105                 110


Leu Ser Val Thr Leu Ala Ser Gly Ser Arg Cys Phe Ser Phe Leu Ser 
        115                 120                 125


Val Ala Trp Gly Phe Val Ser Asp Val Asp Ile Gln Ser Glu Arg Phe 
    130                 135                 140


Arg Ala Leu Gly Ser Ala Arg Phe Thr Leu Gly Thr Val Leu Gly Leu 
145                 150                 155                 160


Ala Thr Leu His Thr Tyr Arg Gly Arg Leu Ser Tyr Leu Pro Ala Thr 
                165                 170                 175


Val Glu Pro Ala Ser Pro Thr Pro Ala His Ser Leu Pro Arg Ala Lys 
            180                 185                 190


Ser Glu Leu Thr Leu Thr Pro Asp Pro Ala Pro Pro Met Ala His Ser 
        195                 200                 205


Pro Leu His Arg Ser Val Ser Asp Leu Pro Leu Pro Leu Pro Gln Pro 
    210                 215                 220


Ala Leu Ala Ser Pro Gly Ser Pro Glu Pro Leu Pro Ile Leu Ser Leu 
225                 230                 235                 240


Asn Gly Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly Gly Ala Gly Asp 
                245                 250                 255


Ala Pro Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro Pro Gly Ser Pro 
            260                 265                 270


Lys Ala Ala Leu His Ser Pro Val Ser Glu Gly Ala Pro Val Ile Pro 
        275                 280                 285


Pro Ser Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala Arg Val Gly Ala 
    290                 295                 300


Ser Thr Cys Gly Pro Pro Asp His Leu Leu Pro Pro Leu Gly Thr Pro 
305                 310                 315                 320


Leu Pro Pro Asp Trp Val Thr Leu Glu Gly Asp Phe Val Leu Met Leu 
                325                 330                 335


Ala Ile Ser Pro Ser His Leu Gly Ala Asp Leu Val Ala Ala Pro His 
            340                 345                 350


Ala Arg Phe Asp Asp Gly Leu Val His Leu Cys Trp Val Arg Ser Gly 
        355                 360                 365


Ile Ser Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala Met Glu Arg Gly 
    370                 375                 380


Ser His Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr Ala Ala Ala Arg 
385                 390                 395                 400


Ala Phe Arg Leu Glu Pro Leu Thr Pro Arg Gly Val Leu Thr Val Asp 
                405                 410                 415


Gly Glu Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln Met His Pro Gly 
            420                 425                 430


Ile Gly Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro Gly Arg Glu Pro 
        435                 440                 445


<210>  9330
<211>  437
<212>  DNA
<213>  Homo sapiens

<400>  9330
gctctccgtg acgctggcct cgggctcccg ctgtttctcc ttcctatctg gggccgccct     60

tacggggcag ggctcagtcc tgacgcttgc cacctgctcc tacccggcca ggatggctga    120

gggcggagtc tattttacgc gtcgcccaat gacaggacct ggaatgtact ggctggggta    180

ggcctcagtg agtcggccgg tcagggcccg cagcctcgcc ccatccactc cggtgcctcc    240

atttagctgg ccaatcagcc caggaggggc aggttccccg gggccggcgc taggatttgc    300

actaatgttc ctctccccgc gggtgggggc ggggaaattc atatcccctg ttcgtctcat    360

gcgcgtcctc cgtccccaat ctaaaaagca attgaaaagg tctatgcaat aaaggcagtc    420

gcttcattcc tctcaga                                                   437


<210>  9331
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  9331

Met Phe Leu Ser Pro Arg Val Gly Ala Gly Lys Phe Ile Ser Pro Val 
1               5                   10                  15


Arg Leu Met Arg Val Leu Arg Pro Gln Ser Lys Lys Gln Leu Lys Arg 
            20                  25                  30


Ser Met Gln 
        35


<210>  9332
<211>  1508
<212>  DNA
<213>  Homo sapiens

<400>  9332
tgacgctggc ctcgggctcc cgctgtttct ccttcctgtc tgtggcctgg ggcttcgtgt     60

cagatgtgga tatccagagc gagcgcttca gggccttggg cagtgcccgc ttcacactgg    120

gcacggtgct gggcctcgcc acactgcaca cctaccgcgg acgcctctcc tacctccccg    180

ccactgtgga acctgcctcg cccacccctg cccatagcct gcctcgtgcc aagtcggagc    240

tgaccctaac cccagaccca gccccgccca tggcccactc acccctgcat cgttctgtgt    300

ctgacctgcc tcttcccctg ccccagcctg ccctggcctc tcctggctcg ccagaacccc    360

tgcccatcct gtccctcaac ggtgggggcc cagagctggc tggggactgg ggtggggctg    420

gggatgctcc gctgtccccg gacccactgc tgtcttcacc tcctggctct cccaaggcag    480

ctctacactc acccgtctcc gaaggggccc ccgtaattcc cccatcctct gggctcccac    540

ttcccacccc tgatgcccgg gtaggggcct ccacctgcgg cccgcccgac cacctgctgc    600

ctccgctggg caccccgctg cccccagact gggtgacgct ggagggggac tttgtgctca    660

tgttggccat ctcgcccagc cacctaggcg ctgacctggt ggcagctccg catgcgcgct    720

tcgacgacgg cctggtgcac ctgtgctggg tgcgtagcgg catctcgcgg gctgcgctgc    780

tgcgcctttt cttggccatg gagcgtggta gccacttcag cctgggctgt ccgcagctgg    840

gctacgccgc ggcccgtgcc ttccgcctag agccgctcac accacgcggc gtgctcacag    900

tggacgggga gcaggtggag tatgggccgc tacaggcaca gatgcaccct ggcatcggta    960

cactgctcac tgggcctcct ggctgcccgg ggcgggattg cgctcgcttt catgggacca   1020

gacgtgatgc tggaaggtgg gcgtcgtcac ggttaaagag aaatgggctc gtcccgaggg   1080

tagtgcctga tcaatgaggg cggggcctgg cgtctgatct ggggccgccc ttacggggca   1140

gggctcagtc ctgacgcttg ccacctgctc ctacccggcc aggatggctg agggcggagt   1200

ctattttacg cgtcgcccaa tgacaggacc tggaatgtac tggctggggt aggcctcagt   1260

gagtcggccg gtcagggccc gcagcctcgc cccatccact ccggtgcctc catttagctg   1320

gccaatcagc ccaggagggg caggttcccc ggggccggcg ctaggatttg cactaatgtt   1380

cctctccccg cgggtggggg cggggaaatt catatcccct gttcgtctca tgcgcgtcct   1440

ccgtccccaa tctaaaaagc aattgaaaag gtctatgcaa taaaggcagt cgcttcattc   1500

ctctcaga                                                            1508


<210>  9333
<211>  275
<212>  PRT
<213>  Homo sapiens

<400>  9333

Met Ala His Ser Pro Leu His Arg Ser Val Ser Asp Leu Pro Leu Pro 
1               5                   10                  15


Leu Pro Gln Pro Ala Leu Ala Ser Pro Gly Ser Pro Glu Pro Leu Pro 
            20                  25                  30


Ile Leu Ser Leu Asn Gly Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly 
        35                  40                  45


Gly Ala Gly Asp Ala Pro Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro 
    50                  55                  60


Pro Gly Ser Pro Lys Ala Ala Leu His Ser Pro Val Ser Glu Gly Ala 
65                  70                  75                  80


Pro Val Ile Pro Pro Ser Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala 
                85                  90                  95


Arg Val Gly Ala Ser Thr Cys Gly Pro Pro Asp His Leu Leu Pro Pro 
            100                 105                 110


Leu Gly Thr Pro Leu Pro Pro Asp Trp Val Thr Leu Glu Gly Asp Phe 
        115                 120                 125


Val Leu Met Leu Ala Ile Ser Pro Ser His Leu Gly Ala Asp Leu Val 
    130                 135                 140


Ala Ala Pro His Ala Arg Phe Asp Asp Gly Leu Val His Leu Cys Trp 
145                 150                 155                 160


Val Arg Ser Gly Ile Ser Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala 
                165                 170                 175


Met Glu Arg Gly Ser His Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr 
            180                 185                 190


Ala Ala Ala Arg Ala Phe Arg Leu Glu Pro Leu Thr Pro Arg Gly Val 
        195                 200                 205


Leu Thr Val Asp Gly Glu Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln 
    210                 215                 220


Met His Pro Gly Ile Gly Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro 
225                 230                 235                 240


Gly Arg Asp Cys Ala Arg Phe His Gly Thr Arg Arg Asp Ala Gly Arg 
                245                 250                 255


Trp Ala Ser Ser Arg Leu Lys Arg Asn Gly Leu Val Pro Arg Val Val 
            260                 265                 270


Pro Asp Gln 
        275


<210>  9334
<211>  1196
<212>  DNA
<213>  Homo sapiens

<400>  9334
agctgaccct aaccccagac ccagccccgc ccatggccca ctcacccctg catcgttctg     60

tgtctgacct gcctcttccc ctgccccagc ctgccctggc ctctcctggc tcgccagaac    120

ccctgcccat cctgtccctc aacggtgggg gcccagagct ggctggggac tggggtgggg    180

ctggggatgc tccgctgtcc ccggacccac tgctgtcttc acctcctggc tctcccaagg    240

cagctctaca ctcacccgtc tccgaagggg cccccgtaat tcccccatcc tctgggctcc    300

cacttcccac ccctgatgcc cgggtagggg cctccacctg cggcccgccc gaccacctgc    360

tgcctccgct gggcaccccg ctgcccccag actgggtgac gctggagggg gactttgtgc    420

tcatgttggc catctcgccc agccacctag gcgctgacct ggtggcagct ccgcatgcgc    480

gcttcgacga cggcctggtg cacctgtgct gggtgcgtag cggcatctcg cgggctgcgc    540

tgctgcgcct tttcttggcc atggagcgtg gtagccactt cagcctgggc tgtccgcagc    600

tgggctacgc cgcggcccgt gccttccgcc tagagccgct cacaccacgc ggcgtgctca    660

cagtggacgg ggagcaggtg gagtatgggc cgctacaggc acagatgcac cctggcatcg    720

gtacactgct cactgggcct cctggctgcc cggggcggga gccctgaaac taaacaagct    780

tggtacccgc cgggggcggg gcctacattc caatggggcg gagcctgagc tagggggtgt    840

ggcctggctg ctagagttgt ggtggcaggg gccctggccc cgtctcagga ttgcgctcgc    900

tttcatggga ccagacgtga tgctggaagg tgggcgtcgt cacggttaaa gagaaatggg    960

ctcgtcccga gggtagtgcc tgatcaatga gggcggggcc tggcgtctga tctggggccg   1020

cccttacggg gcaggttccc cggggccggc gctaggattt gcactaatgt tcctctcccc   1080

gcgggtgggg gcggggaaat tcatatcccc tgttcgtctc atgcgcgtcc tccgtcccca   1140

atctaaaaag caattgaaaa ggtctatgca ataaaggcag tcgcttcatt cctctc       1196


<210>  9335
<211>  244
<212>  PRT
<213>  Homo sapiens

<400>  9335

Met Ala His Ser Pro Leu His Arg Ser Val Ser Asp Leu Pro Leu Pro 
1               5                   10                  15


Leu Pro Gln Pro Ala Leu Ala Ser Pro Gly Ser Pro Glu Pro Leu Pro 
            20                  25                  30


Ile Leu Ser Leu Asn Gly Gly Gly Pro Glu Leu Ala Gly Asp Trp Gly 
        35                  40                  45


Gly Ala Gly Asp Ala Pro Leu Ser Pro Asp Pro Leu Leu Ser Ser Pro 
    50                  55                  60


Pro Gly Ser Pro Lys Ala Ala Leu His Ser Pro Val Ser Glu Gly Ala 
65                  70                  75                  80


Pro Val Ile Pro Pro Ser Ser Gly Leu Pro Leu Pro Thr Pro Asp Ala 
                85                  90                  95


Arg Val Gly Ala Ser Thr Cys Gly Pro Pro Asp His Leu Leu Pro Pro 
            100                 105                 110


Leu Gly Thr Pro Leu Pro Pro Asp Trp Val Thr Leu Glu Gly Asp Phe 
        115                 120                 125


Val Leu Met Leu Ala Ile Ser Pro Ser His Leu Gly Ala Asp Leu Val 
    130                 135                 140


Ala Ala Pro His Ala Arg Phe Asp Asp Gly Leu Val His Leu Cys Trp 
145                 150                 155                 160


Val Arg Ser Gly Ile Ser Arg Ala Ala Leu Leu Arg Leu Phe Leu Ala 
                165                 170                 175


Met Glu Arg Gly Ser His Phe Ser Leu Gly Cys Pro Gln Leu Gly Tyr 
            180                 185                 190


Ala Ala Ala Arg Ala Phe Arg Leu Glu Pro Leu Thr Pro Arg Gly Val 
        195                 200                 205


Leu Thr Val Asp Gly Glu Gln Val Glu Tyr Gly Pro Leu Gln Ala Gln 
    210                 215                 220


Met His Pro Gly Ile Gly Thr Leu Leu Thr Gly Pro Pro Gly Cys Pro 
225                 230                 235                 240


Gly Arg Glu Pro 



<210>  9336
<211>  2942
<212>  DNA
<213>  Homo sapiens

<400>  9336
aggtcagtgt cccgcctccc accgaaaggc aaggcaactt cacgcgctga gcccctcacg     60

cgccctcctg ggccctggcg gacccagagg ccccattggc tgtgcgtctc aaggtgtcgg    120

agacgattgg tccgtgtttg cagccggagg gaggcacgcg gctgggttgc atgcccatag    180

aggctggcgg ggctggacgc gccgggcggg gacccggagg aggggcgcgc gctgtggcgt    240

cgggtgtttt ggtttggatt tttttttccg cgaaagaagt ttgctttggc cacgcctcaa    300

ggcggccgcc tcctcctgcc ccctcctccg cccctccgcg cacacctctc ggtgcagatt    360

gcaaagcgcc ttccgttgcg agagctgcag attttgcaag agccaggctc gcccaccttg    420

tagaaggagc gccttgagtc ccctctcacc ctcggttgca aagagccgac cgcttgatct    480

ggacaccccc tcgcccagat tgcatgatct cccgggaccc tcttgagttg cacgtttctg    540

caccgaggac ctcaaatccc cgtcgctcct aggatttgca gcgttctgga tactggaggg    600

ttgcaggcta cactcgcccg cccctgggca gacactcgtc caaaccactg gagtgtgctg    660

gtgactggca ggccagccct tcgcctctcc atgaacccgt gagcctgggg gcaggtgcca    720

ggcgatggcg cggcctgtga gcgacaggac cccggcccct ctgctgctgg gcggcccggc    780

cgggacaccc cctggcgggg gagcgctgct tgggttgcgg agccttctgc aggggaccag    840

caagcccaaa gagccggcca gctgtctcct gaaggaaaag gagcgcaagg cggccctgcc    900

tgcagccaca acccctgggc caggcctgga gactgcgggc ccggcggatg ccccggctgg    960

ggcagtggtg ggcggagggt ccccgcgggg gcgcccgggg ccggtgcccg ccccgggtct   1020

gttggcgcca ctgctgtggg agcgcacgct gccgttcggc gatgtggagt acgtagacct   1080

ggacgccttc ctgctggagc acgggctccc gcccagcccg ccgccccccg gtggcccgtc   1140

gccggagccg tcgcccgcgc ggacgcccgc accctcccca gggccgggtt cgtgcggctc   1200

ggcttccccc cgctcctctc ctgggcacgc ccccgcccgg gctgccctcg ggaccgccag   1260

cggccaccgc gcaggcctga cctctcggga cacacccagc cctgtggacc cagacaccgt   1320

ggaggtgttg atgacctttg aacccgaccc agctgatctt gccctatcaa gcattcctgg   1380

ccacgagacc tttgaccctc gaagacatcg cttctcagaa gaggaactta agccccagcc   1440

aatcatgaag aaggcaagaa aaatccaggt gccggaggag cagaaggatg agaaatactg   1500

gagccggcgg tacaagaaca acgaggcagc caagcggtcc cgtgacgccc ggcggctcaa   1560

ggagaaccag atatcggtgc gggcggcctt cctggagaag gagaacgccc tgctgcggca   1620

ggaagttgtg gccgtgcgcc aggagctgtc ccactaccgc gccgtgctgt cccgatacca   1680

ggcccagcac ggggccctgt gaggctgccc cacatcccca cctggcggag ctctcctccg   1740

ccttgctgag acttacgccc tgttcccttc ctgccctgtg gcccacgggc cggccagctg   1800

ggtgccccag ggacgtgata atgcagataa atacatttat atttttaaga aaaagcgagc   1860

ctcccccctc ccttgcgggg gcggggaggg ttctctgtgt gtgtccccgg cacgtcaggg   1920

accctatcct cccaccgcct ccgttaacac gatcctgaat aaatcttgag aaccccagag   1980

ccagctgttg tggaagaaga gggcagctcc ctggcatact ggctgcagcc cgtgggcagc   2040

tccgggctgt cgtccataga gggcaggcgc tgctggaagt gctggagtct gagtcctccc   2100

gcgggctgtc ggatggagga agggcagaag gtctgagagg aatgaagcga ctgcctttat   2160

tgcatagacc ttttcaattg ctttttagat tggggacgga ggacgcgcat gagacgaaca   2220

ggggatatga atttccccgc ccccacccgc ggggagagga acattagtgc aaatcctagc   2280

gccggccccg gggaacctgc ccctcctggg ctgattggcc agctaaatgg aggcaccgga   2340

gtggatgggg cgaggctgcg ggccctgacc ggccgactca ctgaggccta ccccagccag   2400

tacattccag gtcctgtcat tgggcgacgc gtaaaataga ctccgccctc agccatcctg   2460

gccgggtagg agcaggtggc aagcgtcagg actgagccct gccccgtaag ggcggcccca   2520

gatcagacgc caggccccgc cctcattgat caggcactac cctcgggacg agcccatttc   2580

tctttaaccg tgacgacgcc caccttccag catcacgtct ggtcccatga aagcgagcgc   2640

aatcctgaga cggggccagg gcccctgcca ccacaactct agcagccagg ccacaccccc   2700

tagctcaggc tccgccccat tggaatgtag gccccgcccc cggcgggtac caagcttgtt   2760

tagtttcagg gctcccgccc cgggcagcca ggaggcccag tgagcagtgt accgatgcca   2820

gggtgcatct gtgcctgtag cggcccatac tccacctgct ccccgtccac tgtgagcacg   2880

ccgcgtggtg tgagcggctc taggcggaag gcacgggccg cggcgtagcc cagctgcgga   2940

ca                                                                  2942


<210>  9337
<211>  325
<212>  PRT
<213>  Homo sapiens

<400>  9337

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175


Thr Ala Ser Gly His Arg Ala Gly Leu Thr Ser Arg Asp Thr Pro Ser 
            180                 185                 190


Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro Asp 
        195                 200                 205


Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe Asp 
    210                 215                 220


Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro Ile 
225                 230                 235                 240


Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp Glu 
                245                 250                 255


Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg Ser 
            260                 265                 270


Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala Ala 
        275                 280                 285


Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala Val 
    290                 295                 300


Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln Ala 
305                 310                 315                 320


Gln His Gly Ala Leu 
                325


<210>  9338
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  9338
gtgttgatga cctttgaacc cgacccagct gatcttgccc tatcaagcat tcctggccac     60

gagacctttg accctcgaag acatcgcttc tcagaagagg aacttaagcc ccagccaatc    120

atgaagaagg agaaccagat atcggtgcgg gcggccttcc tggagaagga gaacgccctg    180

ctgcggcagg aagttgtggc cgtgcgccag gagctgtccc actaccgcgc cgtgctgtcc    240

cgataccagg cccagcacgg ggccctgtga ggctgcccca catccccacc tggcggagct    300

ctcctccgcc ttgctgagac ttacgccctg ttcccttcct gccctgtggc ccacgggccg    360

gccagctggg tgccccaggg acgtgataat gcagataaat acatttatat ttttaagaaa    420

aagcgagcct cccccctccc ttgcgggggc ggggagggtt ctctgtgtgt gtccccggca    480

cgtcagggac cctatcctcc caccgcctcc gttaacacga tcctgaataa atcttgagaa    540

ccccaga                                                              547


<210>  9339
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9339

Met Thr Phe Glu Pro Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro 
1               5                   10                  15


Gly His Glu Thr Phe Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu 
            20                  25                  30


Leu Lys Pro Gln Pro Ile Met Lys Lys Glu Asn Gln Ile Ser Val Arg 
        35                  40                  45


Ala Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val 
    50                  55                  60


Ala Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr 
65                  70                  75                  80


Gln Ala Gln His Gly Ala Leu 
                85


<210>  9340
<211>  883
<212>  DNA
<213>  Homo sapiens

<400>  9340
ggctggctgg tgcttaaagg tacaggcgcc tcctttcgaa ccaatcttct ggaaccttag     60

agcagcttct cctcctcttt ccagcgagta gctcttagac tctaacttga gagcttttca    120

gtgcagtaga ttctttttct ctggacagtc tggggtctaa gcttaggtcg tggattcggc    180

ctgacctctc gggacacacc cagccctgtg gacccagaca ccgtggaggt gttgatgacc    240

tttgaacccg acccagctga tcttgcccta tcaagcattc ctggccacga gacctttgac    300

cctcgaagac atcgcttctc agaagaggaa cttaagcccc agccaatcat gaagaaggca    360

agaaaaatcc aggtgccgga ggagcagaag gatgagaaat actggagccg gcggtacaag    420

aacaacgagg cagccaagcg gtcccgtgac gcccggcggc tcaaggagaa ccagatatcg    480

gtgcgggcgg ccttcctgga gaaggagaac gccctgctgc ggcaggaagt tgtggccgtg    540

cgccaggagc tgtcccacta ccgcgccgtg ctgtcccgat accaggccca gcacggggcc    600

ctgtgaggct gccccacatc cccacctggc ggagctctcc tccgccttgc tgagacttac    660

gccctgttcc cttcctgccc tgtggcccac gggccggcca gctgggtgcc ccagggacgt    720

gataatgcag ataaatacat ttatattttt aagaaaaagc gagcctcccc cctcccttgc    780

gggggcgggg agggttctct gtgtgtgtcc ccggcacgtc agggacccta tcctcccacc    840

gcctccgtta acacgatcct gaataaatct tgagaacccc aga                      883


<210>  9341
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  9341

Met Thr Phe Glu Pro Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro 
1               5                   10                  15


Gly His Glu Thr Phe Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu 
            20                  25                  30


Leu Lys Pro Gln Pro Ile Met Lys Lys Ala Arg Lys Ile Gln Val Pro 
        35                  40                  45


Glu Glu Gln Lys Asp Glu Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn 
    50                  55                  60


Glu Ala Ala Lys Arg Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln 
65                  70                  75                  80


Ile Ser Val Arg Ala Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg 
                85                  90                  95


Gln Glu Val Val Ala Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val 
            100                 105                 110


Leu Ser Arg Tyr Gln Ala Gln His Gly Ala Leu 
        115                 120


<210>  9342
<211>  834
<212>  DNA
<213>  Homo sapiens

<400>  9342
gccgggggaa cgtgagggcg ccgatggcgg gggcctggga ggaagggagg aggagggaag     60

caggcgtcag cacgtgactc ggccctgaac ctgtgtcctt agctggcccc ggctggctgg    120

tgcttaaagg cctgacctct cgggacacac ccagccctgt ggacccagac accgtggagg    180

tgttgatgac ctttgaaccc gacccagctg atcttgccct atcaagcatt cctggccacg    240

agacctttga ccctcgaaga catcgcttct cagaagagga acttaagccc cagccaatca    300

tgaagaaggc aagaaaaatc caggtgccgg aggagcagaa ggatgagaaa tactggagcc    360

ggcggtacaa gaacaacgag gcagccaagc ggtcccgtga cgcccggcgg ctcaaggaga    420

accagatatc ggtgcgggcg gccttcctgg agaaggagaa cgccctgctg cggcaggaag    480

ttgtggccgt gcgccaggag ctgtcccact accgcgccgt gctgtcccga taccaggccc    540

agcacggggc cctgtgaggc tgccccacat ccccacctgg cggagctctc ctccgccttg    600

ctgagactta cgccctgttc ccttcctgcc ctgtggccca cgggccggcc agctgggtgc    660

cccagggacg tgataatgca gataaataca tttatatttt taagaaaaag cgagcctccc    720

ccctcccttg cgggggcggg gagggttctc tgtgtgtgtc cccggcacgt cagggaccct    780

atcctcccac cgcctccgtt aacacgatcc tgaataaatc ttgagaaccc caga          834


<210>  9343
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  9343

Met Thr Phe Glu Pro Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro 
1               5                   10                  15


Gly His Glu Thr Phe Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu 
            20                  25                  30


Leu Lys Pro Gln Pro Ile Met Lys Lys Ala Arg Lys Ile Gln Val Pro 
        35                  40                  45


Glu Glu Gln Lys Asp Glu Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn 
    50                  55                  60


Glu Ala Ala Lys Arg Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln 
65                  70                  75                  80


Ile Ser Val Arg Ala Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg 
                85                  90                  95


Gln Glu Val Val Ala Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val 
            100                 105                 110


Leu Ser Arg Tyr Gln Ala Gln His Gly Ala Leu 
        115                 120


<210>  9344
<211>  1024
<212>  DNA
<213>  Homo sapiens

<400>  9344
cccgtcccct ctttctctgg atctccgccc tgtgcctctc ggactcgggg tctcttctcc     60

atctctatct cccccacctc accctcatcc caacccgtct ttcccggccc gcaggtctcc    120

tgaaggaaaa ggagcgcaag gcggccctgc ctgcagccac aacccctggg ccaggcctgg    180

agactgcggg cccggcggat gccccggctg gggcagtggt gggcggaggg tccccgcggg    240

ggcgcccggg gccggtgccc gccccgggtc tgttggcgcc actgctgtgg gagcgcacgc    300

tgccgttcgg cgatgtggag cctgacctct cgggacacac ccagccctgt ggacccagac    360

accgtggagg tgttgatgac ctttgaaccc gacccagctg atcttgccct atcaagcatt    420

cctggccacg agacctttga ccctcgaaga catcgcttct cagaagagga acttaagccc    480

cagccaatca tgaagaaggc aagaaaaatc caggtgccgg aggagcagaa ggatgagaaa    540

tactggagcc ggcggtacaa gaacaacgag gcagccaagc ggtcccgtga cgcccggcgg    600

ctcaaggaga accagatatc ggtgcgggcg gccttcctgg agaaggagaa cgccctgctg    660

cggcaggaag ttgtggccgt gcgccaggag ctgtcccact accgcgccgt gctgtcccga    720

taccaggccc agcacggggc cctgtgaggc tgccccacat ccccacctgg cggagctctc    780

ctccgccttg ctgagactta cgccctgttc ccttcctgcc ctgtggccca cgggccggcc    840

agctgggtgc cccagggacg tgataatgca gataaataca tttatatttt taagaaaaag    900

cgagcctccc ccctcccttg cgggggcggg gagggttctc tgtgtgtgtc cccggcacgt    960

cagggaccct atcctcccac cgcctccgtt aacacgatcc tgaataaatc ttgagaaccc   1020

caga                                                                1024


<210>  9345
<211>  182
<212>  PRT
<213>  Homo sapiens

<400>  9345

Met Pro Arg Leu Gly Gln Trp Trp Ala Glu Gly Pro Arg Gly Gly Ala 
1               5                   10                  15


Arg Gly Arg Cys Pro Pro Arg Val Cys Trp Arg His Cys Cys Gly Ser 
            20                  25                  30


Ala Arg Cys Arg Ser Ala Met Trp Ser Leu Thr Ser Arg Asp Thr Pro 
        35                  40                  45


Ser Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro 
    50                  55                  60


Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe 
65                  70                  75                  80


Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro 
                85                  90                  95


Ile Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp 
            100                 105                 110


Glu Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg 
        115                 120                 125


Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala 
    130                 135                 140


Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala 
145                 150                 155                 160


Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln 
                165                 170                 175


Ala Gln His Gly Ala Leu 
            180


<210>  9346
<211>  6294
<212>  DNA
<213>  Homo sapiens

<400>  9346
aggtcagtgt cccgcctccc accgaaaggc aaggcaactt cacgcgctga gcccctcacg     60

cgccctcctg ggccctggcg gacccagagg ccccattggc tgtgcgtctc aaggtgtcgg    120

agacgattgg tccgtgtttg cagccggagg gaggcacgcg gctgggttgc atgcccatag    180

aggctggcgg ggctggacgc gccgggcggg gacccggagg aggggcgcgc gctgtggcgt    240

cgggtgtttt ggtttggatt tttttttccg cgaaagaagt ttgctttggc cacgcctcaa    300

ggcggccgcc tcctcctgcc ccctcctccg cccctccgcg cacacctctc ggtgcagatt    360

gcaaagcgcc ttccgttgcg agagctgcag attttgcaag agccaggctc gcccaccttg    420

tagaaggagc gccttgagtc ccctctcacc ctcggttgca aagagccgac cgcttgatct    480

ggacaccccc tcgcccagat tgcatgatct cccgggaccc tcttgagttg cacgtttctg    540

caccgaggac ctcaaatccc cgtcgctcct aggatttgca gcgttctgga tactggaggg    600

ttgcaggcta cactcgcccg cccctgggca gacactcgtc caaaccactg gagtgtgctg    660

gtgactggca ggccagccct tcgcctctcc atgaacccgt gagcctgggg gcaggtgcca    720

ggcgatggcg cggcctgtga gcgacaggac cccggcccct ctgctgctgg gcggcccggc    780

cgggacaccc cctggcgggg gagcgctgct tgggttgcgg agccttctgc aggggaccag    840

caagcccaaa gagccggcca gctgtctcct gaaggaaaag gagcgcaagg cggccctgcc    900

tgcagccaca acccctgggc caggcctgga gactgcgggc ccggcggatg ccccggctgg    960

ggcagtggtg ggcggagggt ccccgcgggg gcgcccgggg ccggtgcccg ccccgggtct   1020

gttggcgcca ctgctgtggg agcgcacgct gccgttcggc gatgtggagt acgtagacct   1080

ggacgccttc ctgctggagc acgggctccc gcccagcccg ccgccccccg gtggcccgtc   1140

gccggagccg tcgcccgcgc ggacgcccgc accctcccca gggccgggtt cgtgcggctc   1200

ggcttccccc cgctcctctc ctgggcacgc ccccgcccgg gctgccctcg ggaccgccag   1260

cggccaccgc gcaggtgcgg cgaagggggc ggggcgggtc ctgacggggc ggggcttgga   1320

ctcagggggc ggggctgtgc gacgctgggg gctgggaccg tgggacctgg ctgcggcctc   1380

gaattctgtg tccagttgtc gagaggtgtc gtgggagggg gccagattcg gtgtctctta   1440

atgggtcagg gaccaatgga tccatggggg aggagagact tggaacccta aattccagga   1500

agcctgccca atgagatttt gtgggttttt ctgtgggact tggggacaaa cgatgtggat   1560

actcgtgaag ccagaactgg aagtccggaa caccagagtt atttactggg gagtggactg   1620

acccccgaat ctgggcccat aatcgatgga actgggatag gactggagcc cctaggtcct   1680

ttacaggggc aaaggcaaag gagaggcaca gaattctgtt tacccaggac ataagagact   1740

ggcagcccag gtccctgggt cccccagtgg ggcgtgctgc agccccgggt cccagagttc   1800

ttcagaaggg aaaacgttag ggatgttgtt tctggatcct ccaattgggg ctggggccaa   1860

gcttcctata ttcctaggag aggcctggga tcccagaatc gtggtagccc agtggcgggg   1920

gttctgggaa ggtccaggag gccgatgctc cccggagagc agggggttgg gaatctttgg   1980

aggttgagtg gaactaagtg actggaagag caagaggaaa gatgtttccc tttgggcaca   2040

ttgaggtctc cagggacgga ctgcaggtcg gggattcctg ggcacacctg ctccaggtcc   2100

gacctccggg ccgaaccagg gccctaccct tcccagcggc acattcctgc gccacgtgag   2160

tcctcccatc cctcctccgc gcttcgcgca ggcgccttca agcgcgaggg gggcggggcc   2220

gggggaacgt gagggcgccg atggcggggg cctgggagga agggaggagg agggaagcag   2280

gcgtcagcac gtgactcggc cctgaacctg tgtccttagc tggccccggc tggctggtgc   2340

ttaaaggtac aggcgcctcc tttcgaacca atcttctgga accttagagc agcttctcct   2400

cctctttcca gcgagtagct cttagactct aacttgagag cttttcagtg cagtagattc   2460

tttttctctg gacagtctgg ggtctaagct taggtcgtgg attcggtaag taggattcag   2520

gctagactgt gcatctgaag tcctgaggtt ttagaagcaa tagccccatc gcttctcggc   2580

cttttggcta agatcaagtg tagaagcaat agccctgatt cgtgtgttac ctagggcaag   2640

tcagttatga ctgggactca gtttccttgt ttgtaaaggt ggatatggct ccatgatctc   2700

taagcatctt tatggcttag gggaaccttc atttttctcg ttattttgga gacggagtct   2760

cgctctgttg tccgggctgg agtgcagtgg tatgatctca gctcactgca acctccacct   2820

ccagggtccg ggttcaagca attctccagc ctcagcctcc ctagtagctg ggcttaccgg   2880

cacccgccac tacacctggg caattttcgt acttttagta aagatgaggt ttctccatgt   2940

tggccatgct ggtcttgaac tcctgactaa aggtgattcg ccgcctcggc ttcccaaact   3000

gctggggtta caggcgtgag ccactgcgcc tggccaaggg aaccttcata ttttatatta   3060

gggagattaa tccctggccg aatttatgct agatcccaga aggactttcc atgtggctat   3120

gataccacag caaaaagtag cttcaggaaa ccccctcctt aaaatacaca ctcagctgac   3180

acgtgctgtt tccccaaggc ctgacctctc gggacacacc cagccctgtg gacccagaca   3240

ccgtggaggt gttgatgacc tttgaacccg acccagctga tcttgcccta tcaagcattc   3300

ctggccacga gacctttgac cctcgaagac atcgcttctc agaagaggaa cttaagcccc   3360

agccaatcat gaagaaggca agaaaaatcc aggtgccgga ggagcagaag gtgagcagag   3420

ctggatgtgg gagatagact tggctggaga catgccccac agccagggag gggccttttc   3480

tcacagtcaa gcctgggctt ctccttggga ttagtgctca gcctctcctg gcctgcagcc   3540

acagattagt cctccttggc cacggggcac aagggggcag gggcctgagg tttataaaga   3600

cagtgtcaac tgggcgaggg gcctcactcg tgtaatccca gcattttagg gggctgaggc   3660

aggaggatct cttgagctcg ggagttcaag accagcctgg gcaacatggc aaaaccccat   3720

ttctacaagc cacttgggag gctgaggtgg gaggactgct tgtgcctggg agattgaggc   3780

tgcagtgagc caagattaca ccactgcact ccagcctggg caacagaggg agaccttgtc   3840

ttaaaacaaa agacagtgtc actgtggggt gctgactcag ccagctctgc taggtctact   3900

tgtagagact tggagcttct cctattactt gggtccagag ctccaccagg cacacttgca   3960

aaggacagtc ttcctttggc aatgggatat cagcctgtgg cctgtctctc cttactcagc   4020

aggcctttga tctctgatgt gggacttcct ttggagtgat tgcatttggc taggatgaag   4080

actgtgccag cccctttagg ccttgtttcc tgggcctgga cttctcactg gtgggagact   4140

tcaggcttct gttagcagcc agtgccactt tctgatttgg ggtgatttga gcagtcattg   4200

catctttgca tgattttgtt ttttgccatt actggagtct tccctagcaa gagttgcttg   4260

ggcttctgtt acaagacttt gtcattccgg gccaggcgcg ttggctcacg cctgtaatcc   4320

tagcacttta ggaggctgag gtgggcggat cacttgaggt caggagtttg agaccagcct   4380

ggccaacatg gtgaaacctc gcctctacta aaagtacaaa aatgttccgg gtgtggtgtc   4440

tcacacctgt aatcacagca ctttgggagg ccgaggcgga cagatcacga gatcaggaga   4500

ccatcctggc caacatggtg aaaccccgtc tctacaaaaa aatacaaaaa ttagctgggc   4560

atggtggcac tcatctgtag tcccagctac ttgggaggct aatgtaggaa aatcgcttga   4620

acccaggaga cggaggttgc agtgagccga gatcgcgcca ctgcactcca gcctgggcga   4680

cagagtgaga actccatctc aaaaaaaaaa aaaaagaaca aaaattagcc ggacatggta   4740

gcgggcacct ataatcccag ctacttggga ggctgaggca ggagaatcgc ttgaacctgg   4800

gaggtggagg ttgcaatgag ccgagatcat gccactgcat tccagcctga acgacagagc   4860

gagactccat ctcaaaaaca aacaagactt tgccataccc ttgcgtaaca catagctact   4920

tgaagcacct aggactggcc tggaagtcag atctacacca gtggtttctc cttctagagg   4980

gccctgttgc tagggactgg atttaccctc acaagcagga actgggcttt aattaaatag   5040

tggagtagag agcatctttc tgagccccgt ggtccttggt tactaaggag gagtcttcct   5100

taggaaccaa cttccaggat gggaggactt taggtataat cctctgggga ggtctcagga   5160

tagtcccctt tcctaagaga cagctcttct ctcagtcagg tcctactggg gaggaggcta   5220

ttctctggcc tcagttcaag gccagcaggt cagaggctgg ccacagtcat tgaaaccact   5280

tagacctcac ttttgtttgc caaggatgga tgaggttgcc ttggcaacca ggtcagaagg   5340

ccccagctct gcgaggattt tatgggacac caaaccccat caccagggca ccaagctttc   5400

cttagcaacc aggatctgga aaggcaatgt gcagggcagg gcagtgctct tcattgggag   5460

aagccctcag accatgaagg ccttgttgct agggaacaag catccttagc aagcaagagc   5520

taactgcatg caggccttta tcatgtgggg agggctgggg tccgctttgc agagtggaga   5580

cttgaagcga gttgcttgag ggtggggggt ctatctcatg cctttactgt tgctaggggc   5640

ccaatctcct tagcaaccag ggccctagaa aggcagaccc ttgggtacct atcccagcag   5700

agacctggtg tggtttaggc cccgctgctg gggctccctt cctctctcgc tgggacctgg   5760

gtccctctgg acctcagtgc tctccccctc ttctcctgca ggatgagaaa tactggagcc   5820

ggcggtacaa gaacaacgag gcagccaagc ggtcccgtga cgcccggcgg ctcaaggaga   5880

accagatatc ggtgcgggcg gccttcctgg agaaggagaa cgccctgctg cggcaggaag   5940

ttgtggccgt gcgccaggag ctgtcccact accgcgccgt gctgtcccga taccaggccc   6000

agcacggggc cctgtgaggc tgccccacat ccccacctgg cggagctctc ctccgccttg   6060

ctgagactta cgccctgttc ccttcctgcc ctgtggccca cgggccggcc agctgggtgc   6120

cccagggacg tgataatgca gataaataca tttatatttt taagaaaaag cgagcctccc   6180

ccctcccttg cgggggcggg gagggttctc tgtgtgtgtc cccggcacgt cagggaccct   6240

atcctcccac cgcctccgtt aacacgatcc tgaataaatc ttgagaaccc caga         6294


<210>  9347
<211>  238
<212>  PRT
<213>  Homo sapiens

<400>  9347

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175


Thr Ala Ser Gly His Arg Ala Gly Ala Ala Lys Gly Ala Gly Arg Val 
            180                 185                 190


Leu Thr Gly Arg Gly Leu Asp Ser Gly Gly Gly Ala Val Arg Arg Trp 
        195                 200                 205


Gly Leu Gly Pro Trp Asp Leu Ala Ala Ala Ser Asn Ser Val Ser Ser 
    210                 215                 220


Cys Arg Glu Val Ser Trp Glu Gly Ala Arg Phe Gly Val Ser 
225                 230                 235


<210>  9348
<211>  1978
<212>  DNA
<213>  Homo sapiens

<400>  9348
aggtcagtgt cccgcctccc accgaaaggc aaggcaactt cacgcgctga gcccctcacg     60

cgccctcctg ggccctggcg gacccagagg ccccattggc tgtgcgtctc aaggtgtcgg    120

agacgattgg tccgtgtttg cagccggagg gaggcacgcg gctgggttgc atgcccatag    180

aggctggcgg ggctggacgc gccgggcggg gacccggagg aggggcgcgc gctgtggcgt    240

cgggtgtttt ggtttggatt tttttttccg cgaaagaagt ttgctttggc cacgcctcaa    300

ggcggccgcc tcctcctgcc ccctcctccg cccctccgcg cacacctctc ggtgcagatt    360

gcaaagcgcc ttccgttgcg agagctgcag attttgcaag agccaggctc gcccaccttg    420

tagaaggagc gccttgagtc ccctctcacc ctcggttgca aagagccgac cgcttgatct    480

ggacaccccc tcgcccagat tgcatgatct cccgggaccc tcttgagttg cacgtttctg    540

caccgaggac ctcaaatccc cgtcgctcct aggatttgca gcgttctgga tactggaggg    600

ttgcaggcta cactcgcccg cccctgggca gacactcgtc caaaccactg gagtgtgctg    660

gtgactggca ggccagccct tcgcctctcc atgaacccgt gagcctgggg gcaggtgcca    720

ggcgatggcg cggcctgtga gcgacaggac cccggcccct ctgctgctgg gcggcccggc    780

cgggacaccc cctggcgggg gagcgctgct tgggttgcgg agccttctgc aggggaccag    840

caagcccaaa gagccggcca gctgtctcct gaaggaaaag gagcgcaagg cggccctgcc    900

tgcagccaca acccctgggc caggcctgga gactgcgggc ccggcggatg ccccggctgg    960

ggcagtggtg ggcggagggt ccccgcgggg gcgcccgggg ccggtgcccg ccccgggtct   1020

gttggcgcca ctgctgtggg agcgcacgct gccgttcggc gatgtggagt acgtagacct   1080

ggacgccttc ctgctggagc acgggctccc gcccagcccg ccgccccccg gtggcccgtc   1140

gccggagccg tcgcccgcgc ggacgcccgc accctcccca gggccgggtt cgtgcggctc   1200

ggcttccccc cgctcctctc ctgggcacgc ccccgcccgg gctgccctcg ggaccgccag   1260

cggccaccgc gcaggcctga cctctcggga cacacccagc cctgtggacc cagacaccgt   1320

ggaggtgttg atgacctttg aacccgaccc agctgatctt gccctatcaa gcattcctgg   1380

ccacgagacc tttgaccctc gaagacatcg cttctcagaa gaggaactta agccccagcc   1440

aatcatgaag aaggcaagaa aaatccaggt gccggaggag cagaaggatg agaaatactg   1500

gagccggcgg tacaagaaca acgaggcagc caagcggtcc cgtgacgccc ggcggctcaa   1560

ggagaaccag atatcggtgc gggcggcctt cctggagaag gagaacgccc tgctgcggca   1620

ggaagttgtg gccgtgcgcc aggagctgtc ccactaccgc gccgtgctgt cccgatacca   1680

ggcccagcac ggggccctgt gaggctgccc cacatcccca cctggcggag ctctcctccg   1740

ccttgctgag acttacgccc tgttcccttc ctgccctgtg gcccacgggc cggccagctg   1800

ggtgccccag ggacgtgata atgcagataa atacatttat atttttaaga aaaagcgagc   1860

ctcccccctc ccttgcgggg gcggggaggg ttctctgtgt gtgtccccgg cacgtcaggg   1920

accctatcct cccaccgcct ccgttaacac gatcctgaat aaatcttgag aaccccag     1978


<210>  9349
<211>  325
<212>  PRT
<213>  Homo sapiens

<400>  9349

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175


Thr Ala Ser Gly His Arg Ala Gly Leu Thr Ser Arg Asp Thr Pro Ser 
            180                 185                 190


Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro Asp 
        195                 200                 205


Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe Asp 
    210                 215                 220


Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro Ile 
225                 230                 235                 240


Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp Glu 
                245                 250                 255


Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg Ser 
            260                 265                 270


Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala Ala 
        275                 280                 285


Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala Val 
    290                 295                 300


Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln Ala 
305                 310                 315                 320


Gln His Gly Ala Leu 
                325


<210>  9350
<211>  753
<212>  DNA
<213>  Homo sapiens

<400>  9350
ggctggctgg tgcttaaagg tacaggcgcc tcctttcgaa ccaatcttct ggaaccttag     60

agcagcttct cctcctcttt ccagcgagta gctcttagac tctaacttga gagcttttca    120

gtgcagtaga ttctttttct ctggacagtc tggggtctaa gcttaggtcg tggattcggc    180

ctgacctctc gggacacacc cagccctgtg gacccagaca ccgtggaggt gttgatgacc    240

tttgaacccg acccagctga tcttgcccta tcaagcattc ctggccacga gacctttgac    300

cctcgaagac atcgcttctc agaagaggaa cttaagcccc agccaatcat gaagaaggca    360

agaaaaatcc aggtgccgga ggagcagaag gatgagaaat actggagccg gcggtacaag    420

aacaacgagg cagccaagcg gtcccgtgac gcccggcggc tcaaggagaa ccagatatcg    480

gtgcgggcgg ccttcctgga gaaggagaac gccctgctgc ggcaggaagt tgtggccgtg    540

cgccaggagc tgtcccacta ccgcgccgtg ctgtcccgat accaggccca gcacggggcc    600

ctgtgaggct gccccacatc cccacctggc ggagctctcc tccgccttgc tgagacttac    660

gccctgttcc cttcctgccc tgtggcccac gggccggcca gctgggtgcc ccagggacgt    720

gataatgcag ataaatacat ttatattttt aag                                 753


<210>  9351
<211>  123
<212>  PRT
<213>  Homo sapiens

<400>  9351

Met Thr Phe Glu Pro Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro 
1               5                   10                  15


Gly His Glu Thr Phe Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu 
            20                  25                  30


Leu Lys Pro Gln Pro Ile Met Lys Lys Ala Arg Lys Ile Gln Val Pro 
        35                  40                  45


Glu Glu Gln Lys Asp Glu Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn 
    50                  55                  60


Glu Ala Ala Lys Arg Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln 
65                  70                  75                  80


Ile Ser Val Arg Ala Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg 
                85                  90                  95


Gln Glu Val Val Ala Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val 
            100                 105                 110


Leu Ser Arg Tyr Gln Ala Gln His Gly Ala Leu 
        115                 120


<210>  9352
<211>  894
<212>  DNA
<213>  Homo sapiens

<400>  9352
cccgtcccct ctttctctgg atctccgccc tgtgcctctc ggactcgggg tctcttctcc     60

atctctatct cccccacctc accctcatcc caacccgtct ttcccggccc gcaggtctcc    120

tgaaggaaaa ggagcgcaag gcggccctgc ctgcagccac aacccctggg ccaggcctgg    180

agactgcggg cccggcggat gccccggctg gggcagtggt gggcggaggg tccccgcggg    240

ggcgcccggg gccggtgccc gccccgggtc tgttggcgcc actgctgtgg gagcgcacgc    300

tgccgttcgg cgatgtggag cctgacctct cgggacacac ccagccctgt ggacccagac    360

accgtggagg tgttgatgac ctttgaaccc gacccagctg atcttgccct atcaagcatt    420

cctggccacg agacctttga ccctcgaaga catcgcttct cagaagagga acttaagccc    480

cagccaatca tgaagaaggc aagaaaaatc caggtgccgg aggagcagaa ggatgagaaa    540

tactggagcc ggcggtacaa gaacaacgag gcagccaagc ggtcccgtga cgcccggcgg    600

ctcaaggaga accagatatc ggtgcgggcg gccttcctgg agaaggagaa cgccctgctg    660

cggcaggaag ttgtggccgt gcgccaggag ctgtcccact accgcgccgt gctgtcccga    720

taccaggccc agcacggggc cctgtgaggc tgccccacat ccccacctgg cggagctctc    780

ctccgccttg ctgagactta cgccctgttc ccttcctgcc ctgtggccca cgggccggcc    840

agctgggtgc cccagggacg tgataatgca gataaataca tttatatttt taag          894


<210>  9353
<211>  182
<212>  PRT
<213>  Homo sapiens

<400>  9353

Met Pro Arg Leu Gly Gln Trp Trp Ala Glu Gly Pro Arg Gly Gly Ala 
1               5                   10                  15


Arg Gly Arg Cys Pro Pro Arg Val Cys Trp Arg His Cys Cys Gly Ser 
            20                  25                  30


Ala Arg Cys Arg Ser Ala Met Trp Ser Leu Thr Ser Arg Asp Thr Pro 
        35                  40                  45


Ser Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro 
    50                  55                  60


Asp Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe 
65                  70                  75                  80


Asp Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro 
                85                  90                  95


Ile Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp 
            100                 105                 110


Glu Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg 
        115                 120                 125


Ser Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala 
    130                 135                 140


Ala Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala 
145                 150                 155                 160


Val Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln 
                165                 170                 175


Ala Gln His Gly Ala Leu 
            180


<210>  9354
<211>  1849
<212>  DNA
<213>  Homo sapiens

<400>  9354
aggtcagtgt cccgcctccc accgaaaggc aaggcaactt cacgcgctga gcccctcacg     60

cgccctcctg ggccctggcg gacccagagg ccccattggc tgtgcgtctc aaggtgtcgg    120

agacgattgg tccgtgtttg cagccggagg gaggcacgcg gctgggttgc atgcccatag    180

aggctggcgg ggctggacgc gccgggcggg gacccggagg aggggcgcgc gctgtggcgt    240

cgggtgtttt ggtttggatt tttttttccg cgaaagaagt ttgctttggc cacgcctcaa    300

ggcggccgcc tcctcctgcc ccctcctccg cccctccgcg cacacctctc ggtgcagatt    360

gcaaagcgcc ttccgttgcg agagctgcag attttgcaag agccaggctc gcccaccttg    420

tagaaggagc gccttgagtc ccctctcacc ctcggttgca aagagccgac cgcttgatct    480

ggacaccccc tcgcccagat tgcatgatct cccgggaccc tcttgagttg cacgtttctg    540

caccgaggac ctcaaatccc cgtcgctcct aggatttgca gcgttctgga tactggaggg    600

ttgcaggcta cactcgcccg cccctgggca gacactcgtc caaaccactg gagtgtgctg    660

gtgactggca ggccagccct tcgcctctcc atgaacccgt gagcctgggg gcaggtgcca    720

ggcgatggcg cggcctgtga gcgacaggac cccggcccct ctgctgctgg gcggcccggc    780

cgggacaccc cctggcgggg gagcgctgct tgggttgcgg agccttctgc aggggaccag    840

caagcccaaa gagccggcca gctgtctcct gaaggaaaag gagcgcaagg cggccctgcc    900

tgcagccaca acccctgggc caggcctgga gactgcgggc ccggcggatg ccccggctgg    960

ggcagtggtg ggcggagggt ccccgcgggg gcgcccgggg ccggtgcccg ccccgggtct   1020

gttggcgcca ctgctgtggg agcgcacgct gccgttcggc gatgtggagt acgtagacct   1080

ggacgccttc ctgctggagc acgggctccc gcccagcccg ccgccccccg gtggcccgtc   1140

gccggagccg tcgcccgcgc ggacgcccgc accctcccca gggccgggtt cgtgcggctc   1200

ggcttccccc cgctcctctc ctgggcacgc ccccgcccgg gctgccctcg ggaccgccag   1260

cggccaccgc gcaggcctga cctctcggga cacacccagc cctgtggacc cagacaccgt   1320

ggaggtgttg atgacctttg aacccgaccc agctgatctt gccctatcaa gcattcctgg   1380

ccacgagacc tttgaccctc gaagacatcg cttctcagaa gaggaactta agccccagcc   1440

aatcatgaag aaggcaagaa aaatccaggt gccggaggag cagaaggatg agaaatactg   1500

gagccggcgg tacaagaaca acgaggcagc caagcggtcc cgtgacgccc ggcggctcaa   1560

ggagaaccag atatcggtgc gggcggcctt cctggagaag gagaacgccc tgctgcggca   1620

ggaagttgtg gccgtgcgcc aggagctgtc ccactaccgc gccgtgctgt cccgatacca   1680

ggcccagcac ggggccctgt gaggctgccc cacatcccca cctggcggag ctctcctccg   1740

ccttgctgag acttacgccc tgttcccttc ctgccctgtg gcccacgggc cggccagctg   1800

ggtgccccag ggacgtgata atgcagataa atacatttat atttttaag               1849


<210>  9355
<211>  325
<212>  PRT
<213>  Homo sapiens

<400>  9355

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175


Thr Ala Ser Gly His Arg Ala Gly Leu Thr Ser Arg Asp Thr Pro Ser 
            180                 185                 190


Pro Val Asp Pro Asp Thr Val Glu Val Leu Met Thr Phe Glu Pro Asp 
        195                 200                 205


Pro Ala Asp Leu Ala Leu Ser Ser Ile Pro Gly His Glu Thr Phe Asp 
    210                 215                 220


Pro Arg Arg His Arg Phe Ser Glu Glu Glu Leu Lys Pro Gln Pro Ile 
225                 230                 235                 240


Met Lys Lys Ala Arg Lys Ile Gln Val Pro Glu Glu Gln Lys Asp Glu 
                245                 250                 255


Lys Tyr Trp Ser Arg Arg Tyr Lys Asn Asn Glu Ala Ala Lys Arg Ser 
            260                 265                 270


Arg Asp Ala Arg Arg Leu Lys Glu Asn Gln Ile Ser Val Arg Ala Ala 
        275                 280                 285


Phe Leu Glu Lys Glu Asn Ala Leu Leu Arg Gln Glu Val Val Ala Val 
    290                 295                 300


Arg Gln Glu Leu Ser His Tyr Arg Ala Val Leu Ser Arg Tyr Gln Ala 
305                 310                 315                 320


Gln His Gly Ala Leu 
                325


<210>  9356
<211>  6164
<212>  DNA
<213>  Homo sapiens

<400>  9356
aggtcagtgt cccgcctccc accgaaaggc aaggcaactt cacgcgctga gcccctcacg     60

cgccctcctg ggccctggcg gacccagagg ccccattggc tgtgcgtctc aaggtgtcgg    120

agacgattgg tccgtgtttg cagccggagg gaggcacgcg gctgggttgc atgcccatag    180

aggctggcgg ggctggacgc gccgggcggg gacccggagg aggggcgcgc gctgtggcgt    240

cgggtgtttt ggtttggatt tttttttccg cgaaagaagt ttgctttggc cacgcctcaa    300

ggcggccgcc tcctcctgcc ccctcctccg cccctccgcg cacacctctc ggtgcagatt    360

gcaaagcgcc ttccgttgcg agagctgcag attttgcaag agccaggctc gcccaccttg    420

tagaaggagc gccttgagtc ccctctcacc ctcggttgca aagagccgac cgcttgatct    480

ggacaccccc tcgcccagat tgcatgatct cccgggaccc tcttgagttg cacgtttctg    540

caccgaggac ctcaaatccc cgtcgctcct aggatttgca gcgttctgga tactggaggg    600

ttgcaggcta cactcgcccg cccctgggca gacactcgtc caaaccactg gagtgtgctg    660

gtgactggca ggccagccct tcgcctctcc atgaacccgt gagcctgggg gcaggtgcca    720

ggcgatggcg cggcctgtga gcgacaggac cccggcccct ctgctgctgg gcggcccggc    780

cgggacaccc cctggcgggg gagcgctgct tgggttgcgg agccttctgc aggggaccag    840

caagcccaaa gagccggcca gctgtctcct gaaggaaaag gagcgcaagg cggccctgcc    900

tgcagccaca acccctgggc caggcctgga gactgcgggc ccggcggatg ccccggctgg    960

ggcagtggtg ggcggagggt ccccgcgggg gcgcccgggg ccggtgcccg ccccgggtct   1020

gttggcgcca ctgctgtggg agcgcacgct gccgttcggc gatgtggagt acgtagacct   1080

ggacgccttc ctgctggagc acgggctccc gcccagcccg ccgccccccg gtggcccgtc   1140

gccggagccg tcgcccgcgc ggacgcccgc accctcccca gggccgggtt cgtgcggctc   1200

ggcttccccc cgctcctctc ctgggcacgc ccccgcccgg gctgccctcg ggaccgccag   1260

cggccaccgc gcaggtgcgg cgaagggggc ggggcgggtc ctgacggggc ggggcttgga   1320

ctcagggggc ggggctgtgc gacgctgggg gctgggaccg tgggacctgg ctgcggcctc   1380

gaattctgtg tccagttgtc gagaggtgtc gtgggagggg gccagattcg gtgtctctta   1440

atgggtcagg gaccaatgga tccatggggg aggagagact tggaacccta aattccagga   1500

agcctgccca atgagatttt gtgggttttt ctgtgggact tggggacaaa cgatgtggat   1560

actcgtgaag ccagaactgg aagtccggaa caccagagtt atttactggg gagtggactg   1620

acccccgaat ctgggcccat aatcgatgga actgggatag gactggagcc cctaggtcct   1680

ttacaggggc aaaggcaaag gagaggcaca gaattctgtt tacccaggac ataagagact   1740

ggcagcccag gtccctgggt cccccagtgg ggcgtgctgc agccccgggt cccagagttc   1800

ttcagaaggg aaaacgttag ggatgttgtt tctggatcct ccaattgggg ctggggccaa   1860

gcttcctata ttcctaggag aggcctggga tcccagaatc gtggtagccc agtggcgggg   1920

gttctgggaa ggtccaggag gccgatgctc cccggagagc agggggttgg gaatctttgg   1980

aggttgagtg gaactaagtg actggaagag caagaggaaa gatgtttccc tttgggcaca   2040

ttgaggtctc cagggacgga ctgcaggtcg gggattcctg ggcacacctg ctccaggtcc   2100

gacctccggg ccgaaccagg gccctaccct tcccagcggc acattcctgc gccacgtgag   2160

tcctcccatc cctcctccgc gcttcgcgca ggcgccttca agcgcgaggg gggcggggcc   2220

gggggaacgt gagggcgccg atggcggggg cctgggagga agggaggagg agggaagcag   2280

gcgtcagcac gtgactcggc cctgaacctg tgtccttagc tggccccggc tggctggtgc   2340

ttaaaggtac aggcgcctcc tttcgaacca atcttctgga accttagagc agcttctcct   2400

cctctttcca gcgagtagct cttagactct aacttgagag cttttcagtg cagtagattc   2460

tttttctctg gacagtctgg ggtctaagct taggtcgtgg attcggtaag taggattcag   2520

gctagactgt gcatctgaag tcctgaggtt ttagaagcaa tagccccatc gcttctcggc   2580

cttttggcta agatcaagtg tagaagcaat agccctgatt cgtgtgttac ctagggcaag   2640

tcagttatga ctgggactca gtttccttgt ttgtaaaggt ggatatggct ccatgatctc   2700

taagcatctt tatggcttag gggaaccttc atttttctcg ttattttgga gacggagtct   2760

cgctctgttg tccgggctgg agtgcagtgg tatgatctca gctcactgca acctccacct   2820

ccagggtccg ggttcaagca attctccagc ctcagcctcc ctagtagctg ggcttaccgg   2880

cacccgccac tacacctggg caattttcgt acttttagta aagatgaggt ttctccatgt   2940

tggccatgct ggtcttgaac tcctgactaa aggtgattcg ccgcctcggc ttcccaaact   3000

gctggggtta caggcgtgag ccactgcgcc tggccaaggg aaccttcata ttttatatta   3060

gggagattaa tccctggccg aatttatgct agatcccaga aggactttcc atgtggctat   3120

gataccacag caaaaagtag cttcaggaaa ccccctcctt aaaatacaca ctcagctgac   3180

acgtgctgtt tccccaaggc ctgacctctc gggacacacc cagccctgtg gacccagaca   3240

ccgtggaggt gttgatgacc tttgaacccg acccagctga tcttgcccta tcaagcattc   3300

ctggccacga gacctttgac cctcgaagac atcgcttctc agaagaggaa cttaagcccc   3360

agccaatcat gaagaaggca agaaaaatcc aggtgccgga ggagcagaag gtgagcagag   3420

ctggatgtgg gagatagact tggctggaga catgccccac agccagggag gggccttttc   3480

tcacagtcaa gcctgggctt ctccttggga ttagtgctca gcctctcctg gcctgcagcc   3540

acagattagt cctccttggc cacggggcac aagggggcag gggcctgagg tttataaaga   3600

cagtgtcaac tgggcgaggg gcctcactcg tgtaatccca gcattttagg gggctgaggc   3660

aggaggatct cttgagctcg ggagttcaag accagcctgg gcaacatggc aaaaccccat   3720

ttctacaagc cacttgggag gctgaggtgg gaggactgct tgtgcctggg agattgaggc   3780

tgcagtgagc caagattaca ccactgcact ccagcctggg caacagaggg agaccttgtc   3840

ttaaaacaaa agacagtgtc actgtggggt gctgactcag ccagctctgc taggtctact   3900

tgtagagact tggagcttct cctattactt gggtccagag ctccaccagg cacacttgca   3960

aaggacagtc ttcctttggc aatgggatat cagcctgtgg cctgtctctc cttactcagc   4020

aggcctttga tctctgatgt gggacttcct ttggagtgat tgcatttggc taggatgaag   4080

actgtgccag cccctttagg ccttgtttcc tgggcctgga cttctcactg gtgggagact   4140

tcaggcttct gttagcagcc agtgccactt tctgatttgg ggtgatttga gcagtcattg   4200

catctttgca tgattttgtt ttttgccatt actggagtct tccctagcaa gagttgcttg   4260

ggcttctgtt acaagacttt gtcattccgg gccaggcgcg ttggctcacg cctgtaatcc   4320

tagcacttta ggaggctgag gtgggcggat cacttgaggt caggagtttg agaccagcct   4380

ggccaacatg gtgaaacctc gcctctacta aaagtacaaa aatgttccgg gtgtggtgtc   4440

tcacacctgt aatcacagca ctttgggagg ccgaggcgga cagatcacga gatcaggaga   4500

ccatcctggc caacatggtg aaaccccgtc tctacaaaaa aatacaaaaa ttagctgggc   4560

atggtggcac tcatctgtag tcccagctac ttgggaggct aatgtaggaa aatcgcttga   4620

acccaggaga cggaggttgc agtgagccga gatcgcgcca ctgcactcca gcctgggcga   4680

cagagtgaga actccatctc aaaaaaaaaa aaaaagaaca aaaattagcc ggacatggta   4740

gcgggcacct ataatcccag ctacttggga ggctgaggca ggagaatcgc ttgaacctgg   4800

gaggtggagg ttgcaatgag ccgagatcat gccactgcat tccagcctga acgacagagc   4860

gagactccat ctcaaaaaca aacaagactt tgccataccc ttgcgtaaca catagctact   4920

tgaagcacct aggactggcc tggaagtcag atctacacca gtggtttctc cttctagagg   4980

gccctgttgc tagggactgg atttaccctc acaagcagga actgggcttt aattaaatag   5040

tggagtagag agcatctttc tgagccccgt ggtccttggt tactaaggag gagtcttcct   5100

taggaaccaa cttccaggat gggaggactt taggtataat cctctgggga ggtctcagga   5160

tagtcccctt tcctaagaga cagctcttct ctcagtcagg tcctactggg gaggaggcta   5220

ttctctggcc tcagttcaag gccagcaggt cagaggctgg ccacagtcat tgaaaccact   5280

tagacctcac ttttgtttgc caaggatgga tgaggttgcc ttggcaacca ggtcagaagg   5340

ccccagctct gcgaggattt tatgggacac caaaccccat caccagggca ccaagctttc   5400

cttagcaacc aggatctgga aaggcaatgt gcagggcagg gcagtgctct tcattgggag   5460

aagccctcag accatgaagg ccttgttgct agggaacaag catccttagc aagcaagagc   5520

taactgcatg caggccttta tcatgtgggg agggctgggg tccgctttgc agagtggaga   5580

cttgaagcga gttgcttgag ggtggggggt ctatctcatg cctttactgt tgctaggggc   5640

ccaatctcct tagcaaccag ggccctagaa aggcagaccc ttgggtacct atcccagcag   5700

agacctggtg tggtttaggc cccgctgctg gggctccctt cctctctcgc tgggacctgg   5760

gtccctctgg acctcagtgc tctccccctc ttctcctgca ggatgagaaa tactggagcc   5820

ggcggtacaa gaacaacgag gcagccaagc ggtcccgtga cgcccggcgg ctcaaggaga   5880

accagatatc ggtgcgggcg gccttcctgg agaaggagaa cgccctgctg cggcaggaag   5940

ttgtggccgt gcgccaggag ctgtcccact accgcgccgt gctgtcccga taccaggccc   6000

agcacggggc cctgtgaggc tgccccacat ccccacctgg cggagctctc ctccgccttg   6060

ctgagactta cgccctgttc ccttcctgcc ctgtggccca cgggccggcc agctgggtgc   6120

cccagggacg tgataatgca gataaataca tttatatttt taag                    6164


<210>  9357
<211>  238
<212>  PRT
<213>  Homo sapiens

<400>  9357

Met Ala Arg Pro Val Ser Asp Arg Thr Pro Ala Pro Leu Leu Leu Gly 
1               5                   10                  15


Gly Pro Ala Gly Thr Pro Pro Gly Gly Gly Ala Leu Leu Gly Leu Arg 
            20                  25                  30


Ser Leu Leu Gln Gly Thr Ser Lys Pro Lys Glu Pro Ala Ser Cys Leu 
        35                  40                  45


Leu Lys Glu Lys Glu Arg Lys Ala Ala Leu Pro Ala Ala Thr Thr Pro 
    50                  55                  60


Gly Pro Gly Leu Glu Thr Ala Gly Pro Ala Asp Ala Pro Ala Gly Ala 
65                  70                  75                  80


Val Val Gly Gly Gly Ser Pro Arg Gly Arg Pro Gly Pro Val Pro Ala 
                85                  90                  95


Pro Gly Leu Leu Ala Pro Leu Leu Trp Glu Arg Thr Leu Pro Phe Gly 
            100                 105                 110


Asp Val Glu Tyr Val Asp Leu Asp Ala Phe Leu Leu Glu His Gly Leu 
        115                 120                 125


Pro Pro Ser Pro Pro Pro Pro Gly Gly Pro Ser Pro Glu Pro Ser Pro 
    130                 135                 140


Ala Arg Thr Pro Ala Pro Ser Pro Gly Pro Gly Ser Cys Gly Ser Ala 
145                 150                 155                 160


Ser Pro Arg Ser Ser Pro Gly His Ala Pro Ala Arg Ala Ala Leu Gly 
                165                 170                 175


Thr Ala Ser Gly His Arg Ala Gly Ala Ala Lys Gly Ala Gly Arg Val 
            180                 185                 190


Leu Thr Gly Arg Gly Leu Asp Ser Gly Gly Gly Ala Val Arg Arg Trp 
        195                 200                 205


Gly Leu Gly Pro Trp Asp Leu Ala Ala Ala Ser Asn Ser Val Ser Ser 
    210                 215                 220


Cys Arg Glu Val Ser Trp Glu Gly Ala Arg Phe Gly Val Ser 
225                 230                 235


<210>  9358
<211>  480
<212>  DNA
<213>  Homo sapiens

<400>  9358
gcacccgaca caccccctcc ctgggacccc aggggtccag actcccggac caaaaggaag     60

aggaggctgg ggcctacact cttgtgaact aagcggggag gacgttgggg acgttggtgc    120

ctgggtcctt agggtggacg ggcttcagag ccggcgcttt tgggtcctgg gcgctaaggg    180

atctaggggc ctaaacacct gagtaattga gtagattaag gttgggaaga tggactcccc    240

gcacgcaggt ttctatggga ccccacccca cggcacctga gtccctaagg gggtagggtg    300

tccgaagtgg gtgagatggg ggttagaact cacagctggc cggctctttg ggcttgctgg    360

tcccctgcag aaggctccgc aacccaagca gcgctccccc gccagggggt gtcccggccg    420

ggccgcccag cagcagagtg tgcgcggagg ggcggaggag ggggcaggag gaggcggccg    480


<210>  9359
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  9359

Met Gly Val Arg Thr His Ser Trp Pro Ala Leu Trp Ala Cys Trp Ser 
1               5                   10                  15


Pro Ala Glu Gly Ser Ala Thr Gln Ala Ala Leu Pro Arg Gln Gly Val 
            20                  25                  30


Ser Arg Pro Gly Arg Pro Ala Ala Glu Cys Ala Arg Arg Gly Gly Gly 
        35                  40                  45


Gly Gly Arg Arg Arg Arg 
    50


<210>  9360
<211>  727
<212>  DNA
<213>  Homo sapiens

<400>  9360
gaggagatgc gggatggaga cctggagtta ggtggcttgg gagagcttaa tgaaaagaga     60

acggagagga ggtgtgggtt aggaaccaag aggtagccct gggggcagca gaaggctgag    120

aggagtagga agatcaggag ctagagggag actggagggt tccgggaaaa gagcagagga    180

aagaggaaag acacagagag acgggagaga gaagaagagt gggtttgaag ggcggatctc    240

agtccctggc tgctttggca tttggggaac tgggactccc tgtggggagg agaggaaagc    300

tggaagtcct ggagggacag gatcctcatt gaccgggccc tcaatatcac ctcccttcag    360

atgcactccc tgagactcct gagccagaat cctccatctc agatcttcca gagcctcagc    420

ggtaacagcc ggcccctgca gcccttggcc cacagggcac tgaggggcaa cagggacccc    480

cggcaccccg agaggcgctg ccgaggcccc aactaccgcc tgcatgtgga tggtgtcccc    540

catggtcgct gagactcccc ttcgaggatt gcacccgccc gtcctaagcc tccccacaag    600

gcgaggggag ttacccctaa aacaaagcta ttaaagggac agaatacttc ctgttttctc    660

agtggtctga ttctaggcgc ggtggggaaa catttgggta ttaaagaaca gacttcttcc    720

ggaaacc                                                              727


<210>  9361
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  9361

Met His Ser Leu Arg Leu Leu Ser Gln Asn Pro Pro Ser Gln Ile Phe 
1               5                   10                  15


Gln Ser Leu Ser Gly Asn Ser Arg Pro Leu Gln Pro Leu Ala His Arg 
            20                  25                  30


Ala Leu Arg Gly Asn Arg Asp Pro Arg His Pro Glu Arg Arg Cys Arg 
        35                  40                  45


Gly Pro Asn Tyr Arg Leu His Val Asp Gly Val Pro His Gly Arg 
    50                  55                  60


<210>  9362
<211>  1842
<212>  DNA
<213>  Homo sapiens

<400>  9362
atcccacccc aagccaaccc gaggagtgtt tgccgctatg agatcacctg ctcccccagc     60

ccaacaacaa aattaaataa caccacggga gaggagagag ggagggggag gagggaggaa    120

gggacaagag agaagagaga ctgaaacagg gagaagaggc aggagaggag gaggtgggga    180

gagcacgaag ctggaggccg acactgaggg agggcgggag gaggtgaaga aggagagagg    240

ggagaagagg caggagctgg aaaggagaga gggaggagga ggaggagatg cgggatggag    300

acctggagtt aggtggcttg ggagagctta atgaaaagag aacggagagg aggtgtgggt    360

taggaaccaa gaggtagccc tgggggcagc agaaggctga gaggagtagg aagatcagga    420

gctagaggga gactggaggg ttccgggaaa agagcagagg aaagaggaaa gacacagaga    480

gacgggagag agaagaagag tgggtttgaa gggcggatct cagtccctgg ctgctttggc    540

atttggggaa ctgggactcc ctgtggggag gagaggaaag ctggaagtcc tggagggaca    600

gggtcccaga aggaggggac agaggagctg agagaggggg gcagggcgtt gggcaggggt    660

ccctcggagg cctcctgggg atgggggctg cagctcgtct gagcgcccct cgagcgctgg    720

tactctgggc tgcactgggg gcagcagctc acatcggacc agcacctgac cccgaggact    780

ggtggagcta caaggataat ctccagggaa acttcgtgcc agggcctcct ttctggggcc    840

tggtgaatgc agcgtggagt ctgtgtgctg tggggaagcg gcagagcccc gtggatgtgg    900

agctgaagag ggttctttat gacccctttc tgcccccatt aaggctcagc actggaggag    960

agaagctccg gggaaccttg tacaacaccg gccgacatgt ctccttcctg cctgcacccc   1020

gacctgtggt caatgtgtct ggaggtcccc tcctttacag ccaccgactc agtgaactgc   1080

ggctgctgtt tggagctcgc gacggagccg gctcggaaca tcagatcaac caccagggct   1140

tctctgctga ggtgcagctc attcacttca accaggaact ctacgggaat ttcagcgctg   1200

cctcccgcgg ccccaatggc ctggccattc tcagcctctt tgtcaacgtt gccagtacct   1260

ctaacccatt cctcagtcgc ctccttaacc gcgacaccat cactcgcatc tcctacaaga   1320

atgatgccta ctttcttcaa gacctgagcc tggagctcct gttccctgaa tccttcggct   1380

tcatcaccta tcagggctct ctcagcaccc cgccctgctc cgagactgtc acctggatcc   1440

tcattgaccg ggccctcaat atcacctccc ttcagatgca ctccctgaga ctcctgagcc   1500

agaatcctcc atctcagatc ttccagagcc tcagcggtaa cagccggccc ctgcagccct   1560

tggcccacag ggcactgagg ggcaacaggg acccccggca ccccgagagg cgctgccgag   1620

gccccaacta ccgcctgcat gtggatggtg tcccccatgg tcgctgagac tccccttcga   1680

ggattgcacc cgcccgtcct aagcctcccc acaaggcgag gggagttacc cctaaaacaa   1740

agctattaaa gggacagaat acttcctgtt ttctcagtgg tctgattcta ggcgcggtgg   1800

ggaaacattt gggtattaaa gaacagactt cttccggaaa cc                      1842


<210>  9363
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  9363

Met Gly Ala Ala Ala Arg Leu Ser Ala Pro Arg Ala Leu Val Leu Trp 
1               5                   10                  15


Ala Ala Leu Gly Ala Ala Ala His Ile Gly Pro Ala Pro Asp Pro Glu 
            20                  25                  30


Asp Trp Trp Ser Tyr Lys Asp Asn Leu Gln Gly Asn Phe Val Pro Gly 
        35                  40                  45


Pro Pro Phe Trp Gly Leu Val Asn Ala Ala Trp Ser Leu Cys Ala Val 
    50                  55                  60


Gly Lys Arg Gln Ser Pro Val Asp Val Glu Leu Lys Arg Val Leu Tyr 
65                  70                  75                  80


Asp Pro Phe Leu Pro Pro Leu Arg Leu Ser Thr Gly Gly Glu Lys Leu 
                85                  90                  95


Arg Gly Thr Leu Tyr Asn Thr Gly Arg His Val Ser Phe Leu Pro Ala 
            100                 105                 110


Pro Arg Pro Val Val Asn Val Ser Gly Gly Pro Leu Leu Tyr Ser His 
        115                 120                 125


Arg Leu Ser Glu Leu Arg Leu Leu Phe Gly Ala Arg Asp Gly Ala Gly 
    130                 135                 140


Ser Glu His Gln Ile Asn His Gln Gly Phe Ser Ala Glu Val Gln Leu 
145                 150                 155                 160


Ile His Phe Asn Gln Glu Leu Tyr Gly Asn Phe Ser Ala Ala Ser Arg 
                165                 170                 175


Gly Pro Asn Gly Leu Ala Ile Leu Ser Leu Phe Val Asn Val Ala Ser 
            180                 185                 190


Thr Ser Asn Pro Phe Leu Ser Arg Leu Leu Asn Arg Asp Thr Ile Thr 
        195                 200                 205


Arg Ile Ser Tyr Lys Asn Asp Ala Tyr Phe Leu Gln Asp Leu Ser Leu 
    210                 215                 220


Glu Leu Leu Phe Pro Glu Ser Phe Gly Phe Ile Thr Tyr Gln Gly Ser 
225                 230                 235                 240


Leu Ser Thr Pro Pro Cys Ser Glu Thr Val Thr Trp Ile Leu Ile Asp 
                245                 250                 255


Arg Ala Leu Asn Ile Thr Ser Leu Gln Met His Ser Leu Arg Leu Leu 
            260                 265                 270


Ser Gln Asn Pro Pro Ser Gln Ile Phe Gln Ser Leu Ser Gly Asn Ser 
        275                 280                 285


Arg Pro Leu Gln Pro Leu Ala His Arg Ala Leu Arg Gly Asn Arg Asp 
    290                 295                 300


Pro Arg His Pro Glu Arg Arg Cys Arg Gly Pro Asn Tyr Arg Leu His 
305                 310                 315                 320


Val Asp Gly Val Pro His Gly Arg 
                325


<210>  9364
<211>  446
<212>  DNA
<213>  Homo sapiens

<400>  9364
tgctcccagg ggcggggttt cctgcgtgac gtcaccaaga ccattcacta ttcactccca     60

gtttcccacc ctccttccac tgcagatgca ctccctgaga ctcctgagcc agaatcctcc    120

atctcagatc ttccagagcc tcagcggtaa cagccggccc ctgcagccct tggcccacag    180

ggcactgagg ggcaacaggg acccccggca ccccgagagg cgctgccgag gccccaacta    240

ccgcctgcat gtggatggtg tcccccatgg tcgctgagac tccccttcga ggattgcacc    300

cgcccgtcct aagcctcccc acaaggcgag gggagttacc cctaaaacaa agctattaaa    360

gggacagaat acttcctgtt ttctcagtgg tctgattcta ggcgcggtgg ggaaacattt    420

gggtattaaa gaacagactt cttccg                                         446


<210>  9365
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  9365

Met His Ser Leu Arg Leu Leu Ser Gln Asn Pro Pro Ser Gln Ile Phe 
1               5                   10                  15


Gln Ser Leu Ser Gly Asn Ser Arg Pro Leu Gln Pro Leu Ala His Arg 
            20                  25                  30


Ala Leu Arg Gly Asn Arg Asp Pro Arg His Pro Glu Arg Arg Cys Arg 
        35                  40                  45


Gly Pro Asn Tyr Arg Leu His Val Asp Gly Val Pro His Gly Arg 
    50                  55                  60


<210>  9366
<211>  598
<212>  DNA
<213>  Homo sapiens

<400>  9366
cggaagaagt ctgttcttta atacccaaat gtttccccac cgcgcctaga atcagaccac     60

tgagaaaaca ggaagtattc tgtcccttta atagctttgt tttaggggta actcccctcg    120

ccttgtgggg aggcttagga cgggcgggtg caatcctcga aggggagtct cagcgaccat    180

gggggacacc atccactaga tgtcaggctg aaggagatga tgaaactctg taagccgaag    240

aacatgggga aagaggagac acaggaagcc acgctatccc cacagggacc cctgccagcc    300

aggccacccg caacggtgtg ggacgtgagt gccgttgccc ccggcggtcc agcagcagga    360

cagccccgag cagcctggcc taggaggctc accgcagccg tcaagggatt ctgggccacc    420

cgcccttcct tctccacctt ctacttcgtc tttgccattt ttgtggtgtc caccatcttt    480

cactgccacc agcacctggc tctggtgcct gcgccctggg catactcagc ccgtgtggtc    540

ctggccccca gacacctgcc ccgggaggac ctgttcacta tcaactccaa gggccgcc      598


<210>  9367
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  9367

Met Met Lys Leu Cys Lys Pro Lys Asn Met Gly Lys Glu Glu Thr Gln 
1               5                   10                  15


Glu Ala Thr Leu Ser Pro Gln Gly Pro Leu Pro Ala Arg Pro Pro Ala 
            20                  25                  30


Thr Val Trp Asp Val Ser Ala Val Ala Pro Gly Gly Pro Ala Ala Gly 
        35                  40                  45


Gln Pro Arg Ala Ala Trp Pro Arg Arg Leu Thr Ala Ala Val Lys Gly 
    50                  55                  60


Phe Trp Ala Thr Arg Pro Ser Phe Ser Thr Phe Tyr Phe Val Phe Ala 
65                  70                  75                  80


Ile Phe Val Val Ser Thr Ile Phe His Cys His Gln His Leu Ala Leu 
                85                  90                  95


Val Pro Ala Pro Trp Ala Tyr Ser Ala Arg Val Val Leu Ala Pro Arg 
            100                 105                 110


His Leu Pro Arg Glu Asp Leu Phe Thr Ile Asn Ser Lys Gly 
        115                 120                 125


<210>  9368
<211>  697
<212>  DNA
<213>  Homo sapiens

<400>  9368
cggaagaagt ctgttcttta atacccaaat gtttccccac cgcgcctaga atcagaccac     60

tgagaaaaca ggaagtattc tgtcccttta atagctttgt tttaggggta actcccctcg    120

ccttgtgggg aggcttagga cgggcgggtg caatcctcga aggggagtct cagcgaccat    180

gggggacacc atccactccg tcaagggatt ctgggccacc cgcccttcct tctccacctt    240

ctacttcgtc tttgccattt ttgtggtgtc caccatcttt cactgccacc agcacctggc    300

tctggtgcct gcgccctggg catactcagc ccgtgtggtc ctggccccca gacacctgcc    360

ccgggaggac ctgttcacta tcaactccaa gggccgcctg gggaaccaga tgggcgagta    420

cgccacgctg tacgccctgg ccaagatgaa cgggcggccc gccttcatcc cggcccagat    480

gcacagcacc ctggccccca tcttcagaat caccctgccg gtgctgcaca gcgccacggc    540

cagcaggatc ccctggcaga actaccacct gaacgactgg atggaggagg agtaccgcca    600

catcccgggg cgctgtgtcc gcctcacggg ctacccctgc tcctggacct tctaccacca    660

cctccgccag gagatcctcc aggagttcac cctgcac                             697


<210>  9369
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  9369

Met Gly Asp Thr Ile His Ser Val Lys Gly Phe Trp Ala Thr Arg Pro 
1               5                   10                  15


Ser Phe Ser Thr Phe Tyr Phe Val Phe Ala Ile Phe Val Val Ser Thr 
            20                  25                  30


Ile Phe His Cys His Gln His Leu Ala Leu Val Pro Ala Pro Trp Ala 
        35                  40                  45


Tyr Ser Ala Arg Val Val Leu Ala Pro Arg His Leu Pro Arg Glu Asp 
    50                  55                  60


Leu Phe Thr Ile Asn Ser Lys Gly Arg Leu Gly Asn Gln Met Gly Glu 
65                  70                  75                  80


Tyr Ala Thr Leu Tyr Ala Leu Ala Lys Met Asn Gly Arg Pro Ala Phe 
                85                  90                  95


Ile Pro Ala Gln Met His Ser Thr Leu Ala Pro Ile Phe Arg Ile Thr 
            100                 105                 110


Leu Pro Val Leu His Ser Ala Thr Ala Ser Arg Ile Pro Trp Gln Asn 
        115                 120                 125


Tyr His Leu Asn Asp Trp Met Glu Glu Glu Tyr Arg His Ile Pro Gly 
    130                 135                 140


Arg Cys Val Arg Leu Thr Gly Tyr Pro Cys Ser Trp Thr Phe Tyr His 
145                 150                 155                 160


His Leu Arg Gln Glu Ile Leu Gln Glu Phe Thr Leu 
                165                 170


<210>  9370
<211>  381
<212>  DNA
<213>  Homo sapiens

<400>  9370
tgctcccagg ggcggggttt cctgcgtgac gtcaccaaga ccattcacta ttcactccca     60

gtttcccacc ctccttccac tgcagatgca ctccctgaga ctcctgagcc agaatcctcc    120

atctcagatc ttccagagcc tcagcggtaa cagccggccc ctgcagccct tggcccacag    180

ggcactgagg ggcaacaggg acccccggca ccccgagagg cgctgccgag gccccaacta    240

ccgcctgcat gtggatggtg tcccccatgg tcgctgagac tccccttcga ggattgcacc    300

cgcccgtcct aagcctcccc acaaggcgag gggagttacc cctaaaacaa agctattaaa    360

gggacagaat acttcctgtt t                                              381


<210>  9371
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  9371

Met His Ser Leu Arg Leu Leu Ser Gln Asn Pro Pro Ser Gln Ile Phe 
1               5                   10                  15


Gln Ser Leu Ser Gly Asn Ser Arg Pro Leu Gln Pro Leu Ala His Arg 
            20                  25                  30


Ala Leu Arg Gly Asn Arg Asp Pro Arg His Pro Glu Arg Arg Cys Arg 
        35                  40                  45


Gly Pro Asn Tyr Arg Leu His Val Asp Gly Val Pro His Gly Arg 
    50                  55                  60


<210>  9372
<211>  656
<212>  DNA
<213>  Homo sapiens

<400>  9372
gaggagatgc gggatggaga cctggagtta ggtggcttgg gagagcttaa tgaaaagaga     60

acggagagga ggtgtgggtt aggaaccaag aggtagccct gggggcagca gaaggctgag    120

aggagtagga agatcaggag ctagagggag actggagggt tccgggaaaa gagcagagga    180

aagaggaaag acacagagag acgggagaga gaagaagagt gggtttgaag ggcggatctc    240

agtccctggc tgctttggca tttggggaac tgggactccc tgtggggagg agaggaaagc    300

tggaagtcct ggagggacag gatcctcatt gaccgggccc tcaatatcac ctcccttcag    360

atgcactccc tgagactcct gagccagaat cctccatctc agatcttcca gagcctcagc    420

ggtaacagcc ggcccctgca gcccttggcc cacagggcac tgaggggcaa cagggacccc    480

cggcaccccg agaggcgctg ccgaggcccc aactaccgcc tgcatgtgga tggtgtcccc    540

catggtcgct gagactcccc ttcgaggatt gcacccgccc gtcctaagcc tccccacaag    600

gcgaggggag ttacccctaa aacaaagcta ttaaagggac agaatacttc ctgttt        656


<210>  9373
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  9373

Met His Ser Leu Arg Leu Leu Ser Gln Asn Pro Pro Ser Gln Ile Phe 
1               5                   10                  15


Gln Ser Leu Ser Gly Asn Ser Arg Pro Leu Gln Pro Leu Ala His Arg 
            20                  25                  30


Ala Leu Arg Gly Asn Arg Asp Pro Arg His Pro Glu Arg Arg Cys Arg 
        35                  40                  45


Gly Pro Asn Tyr Arg Leu His Val Asp Gly Val Pro His Gly Arg 
    50                  55                  60


<210>  9374
<211>  1771
<212>  DNA
<213>  Homo sapiens

<400>  9374
atcccacccc aagccaaccc gaggagtgtt tgccgctatg agatcacctg ctcccccagc     60

ccaacaacaa aattaaataa caccacggga gaggagagag ggagggggag gagggaggaa    120

gggacaagag agaagagaga ctgaaacagg gagaagaggc aggagaggag gaggtgggga    180

gagcacgaag ctggaggccg acactgaggg agggcgggag gaggtgaaga aggagagagg    240

ggagaagagg caggagctgg aaaggagaga gggaggagga ggaggagatg cgggatggag    300

acctggagtt aggtggcttg ggagagctta atgaaaagag aacggagagg aggtgtgggt    360

taggaaccaa gaggtagccc tgggggcagc agaaggctga gaggagtagg aagatcagga    420

gctagaggga gactggaggg ttccgggaaa agagcagagg aaagaggaaa gacacagaga    480

gacgggagag agaagaagag tgggtttgaa gggcggatct cagtccctgg ctgctttggc    540

atttggggaa ctgggactcc ctgtggggag gagaggaaag ctggaagtcc tggagggaca    600

gggtcccaga aggaggggac agaggagctg agagaggggg gcagggcgtt gggcaggggt    660

ccctcggagg cctcctgggg atgggggctg cagctcgtct gagcgcccct cgagcgctgg    720

tactctgggc tgcactgggg gcagcagctc acatcggacc agcacctgac cccgaggact    780

ggtggagcta caaggataat ctccagggaa acttcgtgcc agggcctcct ttctggggcc    840

tggtgaatgc agcgtggagt ctgtgtgctg tggggaagcg gcagagcccc gtggatgtgg    900

agctgaagag ggttctttat gacccctttc tgcccccatt aaggctcagc actggaggag    960

agaagctccg gggaaccttg tacaacaccg gccgacatgt ctccttcctg cctgcacccc   1020

gacctgtggt caatgtgtct ggaggtcccc tcctttacag ccaccgactc agtgaactgc   1080

ggctgctgtt tggagctcgc gacggagccg gctcggaaca tcagatcaac caccagggct   1140

tctctgctga ggtgcagctc attcacttca accaggaact ctacgggaat ttcagcgctg   1200

cctcccgcgg ccccaatggc ctggccattc tcagcctctt tgtcaacgtt gccagtacct   1260

ctaacccatt cctcagtcgc ctccttaacc gcgacaccat cactcgcatc tcctacaaga   1320

atgatgccta ctttcttcaa gacctgagcc tggagctcct gttccctgaa tccttcggct   1380

tcatcaccta tcagggctct ctcagcaccc cgccctgctc cgagactgtc acctggatcc   1440

tcattgaccg ggccctcaat atcacctccc ttcagatgca ctccctgaga ctcctgagcc   1500

agaatcctcc atctcagatc ttccagagcc tcagcggtaa cagccggccc ctgcagccct   1560

tggcccacag ggcactgagg ggcaacaggg acccccggca ccccgagagg cgctgccgag   1620

gccccaacta ccgcctgcat gtggatggtg tcccccatgg tcgctgagac tccccttcga   1680

ggattgcacc cgcccgtcct aagcctcccc acaaggcgag gggagttacc cctaaaacaa   1740

agctattaaa gggacagaat acttcctgtt t                                  1771


<210>  9375
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  9375

Met Gly Ala Ala Ala Arg Leu Ser Ala Pro Arg Ala Leu Val Leu Trp 
1               5                   10                  15


Ala Ala Leu Gly Ala Ala Ala His Ile Gly Pro Ala Pro Asp Pro Glu 
            20                  25                  30


Asp Trp Trp Ser Tyr Lys Asp Asn Leu Gln Gly Asn Phe Val Pro Gly 
        35                  40                  45


Pro Pro Phe Trp Gly Leu Val Asn Ala Ala Trp Ser Leu Cys Ala Val 
    50                  55                  60


Gly Lys Arg Gln Ser Pro Val Asp Val Glu Leu Lys Arg Val Leu Tyr 
65                  70                  75                  80


Asp Pro Phe Leu Pro Pro Leu Arg Leu Ser Thr Gly Gly Glu Lys Leu 
                85                  90                  95


Arg Gly Thr Leu Tyr Asn Thr Gly Arg His Val Ser Phe Leu Pro Ala 
            100                 105                 110


Pro Arg Pro Val Val Asn Val Ser Gly Gly Pro Leu Leu Tyr Ser His 
        115                 120                 125


Arg Leu Ser Glu Leu Arg Leu Leu Phe Gly Ala Arg Asp Gly Ala Gly 
    130                 135                 140


Ser Glu His Gln Ile Asn His Gln Gly Phe Ser Ala Glu Val Gln Leu 
145                 150                 155                 160


Ile His Phe Asn Gln Glu Leu Tyr Gly Asn Phe Ser Ala Ala Ser Arg 
                165                 170                 175


Gly Pro Asn Gly Leu Ala Ile Leu Ser Leu Phe Val Asn Val Ala Ser 
            180                 185                 190


Thr Ser Asn Pro Phe Leu Ser Arg Leu Leu Asn Arg Asp Thr Ile Thr 
        195                 200                 205


Arg Ile Ser Tyr Lys Asn Asp Ala Tyr Phe Leu Gln Asp Leu Ser Leu 
    210                 215                 220


Glu Leu Leu Phe Pro Glu Ser Phe Gly Phe Ile Thr Tyr Gln Gly Ser 
225                 230                 235                 240


Leu Ser Thr Pro Pro Cys Ser Glu Thr Val Thr Trp Ile Leu Ile Asp 
                245                 250                 255


Arg Ala Leu Asn Ile Thr Ser Leu Gln Met His Ser Leu Arg Leu Leu 
            260                 265                 270


Ser Gln Asn Pro Pro Ser Gln Ile Phe Gln Ser Leu Ser Gly Asn Ser 
        275                 280                 285


Arg Pro Leu Gln Pro Leu Ala His Arg Ala Leu Arg Gly Asn Arg Asp 
    290                 295                 300


Pro Arg His Pro Glu Arg Arg Cys Arg Gly Pro Asn Tyr Arg Leu His 
305                 310                 315                 320


Val Asp Gly Val Pro His Gly Arg 
                325


<210>  9376
<211>  275
<212>  DNA
<213>  Homo sapiens

<400>  9376
cccccccccc catgaagacc ttcaagtagt tcagcctact gctgaatctg gacgtcccga     60

ttcccccctc ctattggctt cttgtggttc agcccagtgc ttctcgacct agtacattct    120

ggttccccgc tcgcagactt ccgacgtgga tggtgtcccc catggtcgct gagactcccc    180

ttcgaggatt gcacccgccc gtcctaagcc tccccacaag gcgaggggag ttacccctaa    240

aacaaagcta ttaaagggac agaatacttc ctgtt                               275


<210>  9377
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  9377

Met Val Ser Pro Met Val Ala Glu Thr Pro Leu Arg Gly Leu His Pro 
1               5                   10                  15


Pro Val Leu Ser Leu Pro Thr Arg Arg Gly Glu Leu Pro Leu Lys Gln 
            20                  25                  30


Ser Tyr 



<210>  9378
<211>  383
<212>  DNA
<213>  Homo sapiens

<400>  9378
gaggagatgc gggatggaga cctggagtta ggtggcttgg gagagcttaa tgaaaagaga     60

acggagagga ggtgtgggtt aggaaccaag aggtagccct gggggcagca gaaggctgag    120

aggagtagga agatcaggag ctagagggag actggagggt tccgggaaaa gagcagagga    180

aagaggaaag acacagagag acgggagaga gaagaagagt gggtttgaag ggcggatctc    240

agtccctggc tgctttggca tttggggaac tgggactccc tgtggggagg agaggattgc    300

acccgcccgt cctaagcctc cccacaaggc gaggggagtt acccctaaaa caaagctatt    360

aaagggacag aatacttcct gtt                                            383


<210>  9379
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  9379

Glu Pro Arg Gly Ser Pro Gly Gly Ser Arg Arg Leu Arg Gly Val Gly 
1               5                   10                  15


Arg Ser Gly Ala Arg Gly Arg Leu Glu Gly Ser Gly Lys Arg Ala Glu 
            20                  25                  30


Glu Arg Gly Lys Thr Gln Arg Asp Gly Arg Glu Lys Lys Ser Gly Phe 
        35                  40                  45


Glu Gly Arg Ile Ser Val Pro Gly Cys Phe Gly Ile Trp Gly Thr Gly 
    50                  55                  60


Thr Pro Cys Gly Glu Glu Arg Ile Ala Pro Ala Arg Pro Lys Pro Pro 
65                  70                  75                  80


His Lys Ala Arg Gly Val Thr Pro Lys Thr Lys Leu Leu Lys Gly Gln 
                85                  90                  95


Asn Thr Ser 



<210>  9380
<211>  181
<212>  DNA
<213>  Homo sapiens

<400>  9380
agagactgaa acagggagaa gaggcaggag aggaggaggt ggggagagca cgaagctggt     60

gaatgcagcg tggagtctgt gtgctgtggg gaagcggcag agccccgtgg atgtggagct    120

gaagagggtt ctttatgacc cctttctgcc cccattaagg ctcagcactg gaggagagaa    180

g                                                                    181


<210>  9381
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  9381

Glu Thr Glu Thr Gly Arg Arg Gly Arg Arg Gly Gly Gly Gly Glu Ser 
1               5                   10                  15


Thr Lys Leu Val Asn Ala Ala Trp Ser Leu Cys Ala Val Gly Lys Arg 
            20                  25                  30


Gln Ser Pro Val Asp Val Glu Leu Lys Arg Val Leu Tyr Asp Pro Phe 
        35                  40                  45


Leu Pro Pro Leu Arg Leu Ser Thr Gly Gly Glu 
    50                  55


<210>  9382
<211>  1117
<212>  DNA
<213>  Homo sapiens

<400>  9382
gggacaagag agaagagaga ctgaaacagg gagaagaggc aggagaggag gaggtgggga     60

gagcacgaag ctggaggccg acactgaggg agggcgggag gaggtgaaga aggagagagg    120

ggagaagagg caggagctgg aaaggagaga gggaggagga ggaggagatg cgggatggag    180

acctggagtt aggtggcttg ggagagctta atgaaaagag aacggagagg aggtgtgggt    240

taggaaccaa gaggtagccc tgggggcagc agaaggctga gaggagtagg aagatcagga    300

gctagaggga gactggaggg ttccgggaaa agagcagagg aaagaggaaa gacacagaga    360

gacgggagag agaagaagag tgggtttgaa gggcggatct cagtccctgg ctgctttggc    420

atttggggaa ctgggactcc ctgtggggag gagaggaaag ctggaagtcc tggagggaca    480

gggtcccaga aggaggggac agaggagctg agagaggggg gcagggcgtt gggcaggggt    540

ccctcggagg cctcctgggg atgggggctg cagctcgtct gagcgcccct cgagcgctgg    600

tactctgggc tgcactgggg gcagcagctc acatcggacc agcacctgac cccgaggact    660

ggtggagcta caaggataat ctccagggaa acttcgtgcc aggtgccgcc aaggcgggga    720

cccaggagtc cggccctccc ggcgcctcct tcttcagact caggaacctg ggttcccagc    780

tccctcctcc cccccaggac caggagtccc agccccctcc tctgtccctc aggagtcggg    840

ccagcttctg aaccccaggg gctcaccatg ggacattata catgcgcatt tcaagtagtg    900

agtgggagtg agtggaagga aagtgtgggg gtggagatta tgtgtgtgtt tgccgggaga    960

ggaaggtcct ggctcctgct aggaaccaga ggctgggtgg ccccgtcccc caccttgtcc   1020

agccttctct tgcagctcct ctccccaaca cattaataat aatccagctg tgggataaga   1080

gcgattaaaa aaaagaacta caactcccac ggggctc                            1117


<210>  9383
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  9383

Met Gly Ala Ala Ala Arg Leu Ser Ala Pro Arg Ala Leu Val Leu Trp 
1               5                   10                  15


Ala Ala Leu Gly Ala Ala Ala His Ile Gly Pro Ala Pro Asp Pro Glu 
            20                  25                  30


Asp Trp Trp Ser Tyr Lys Asp Asn Leu Gln Gly Asn Phe Val Pro Gly 
        35                  40                  45


Ala Ala Lys Ala Gly Thr Gln Glu Ser Gly Pro Pro Gly Ala Ser Phe 
    50                  55                  60


Phe Arg Leu Arg Asn Leu Gly Ser Gln Leu Pro Pro Pro Pro Gln Asp 
65                  70                  75                  80


Gln Glu Ser Gln Pro Pro Pro Leu Ser Leu Arg Ser Arg Ala Ser Phe 
                85                  90                  95


<210>  9384
<211>  1854
<212>  DNA
<213>  Homo sapiens

<400>  9384
cagccacgcc actccctcct gagagcccac cgcgccacag cttggaggaa gagcctgcgg     60

ggaactggct gcaggacgct ctcttcttga gtgcaggtgc tggctctgct gtgaccatgc    120

ccgtgacctt tgccctcctg ctcctcctgg gccaggccac tgcggaccca tgctacgatc    180

cacagggccg cccccaattc tgcctcccgc cagtgacaca gctggctgcc gtggcggcct    240

cctgccctca ggcctgtgcc ctgtccccag gaaaccacct tggcgccagg gaaacctgca    300

atggcagcct gactttggcc ctgggtggcc ccttcctcct gacatctgtc agcttgcgct    360

tctgtacccc aggaccccca gccctcatcc tgtctgctgc ctgggcctca gggggtccct    420

ggaggctgct gtggcacagg cccgcctggc ctggggcctt agggggccct gaaagggtga    480

ccttccactc cacaccaggt cctaaggcca ctgtggcggc cagccacctc cgtgtggagt    540

ttgggggcca ggccgggcta gcggcagctg ggctgagagg ccgctgccag tgtcatggcc    600

acgctgcccg ctgtgccgcc cgtgcccggc ccccccgctg ccactgccgc caccatacca    660

ctggcccggg gtgcgagagc tgccgcccgt cccatcgaga ctggccctgg cggcctgcca    720

cgccccggca cccccaccct tgcctaccct gctcctgcaa ccagcacgcc cgacgctgcc    780

ggttcaactc tgagctgttc agactgtcgg gcggccggag tgggggtgtt tgtgagcggt    840

gccgccacca cacagctggg cggcactgcc actactgcca acctgggttc tggagggacc    900

ctagccagcc tatcttcagc cgcagggcct gcagagcctg ccagtgccac cctattgggg    960

caacaggagg aacctgcaac cagaccagtg ggcagtgcac ctgcaagtta ggggtcacag   1020

gcctgacctg caaccgctgt ggccctggct accagcagag ccgctccccc aggatgccct   1080

gccagcgaat tccagaggca acaaccaccc ttgccactac tcctggtgct tatagctctg   1140

accctcagtg tcaaaactac tgcaatatgt cggacaccag ggtacacatg agccttcgga   1200

ggtactgcca gcaggaccat gttctccgcg cgcaggtgct agcgtccgag gcggcgggcc   1260

cggcatggca gcggctggcc gtgcgcgtgc tggccgttta caagcagcgg gcgcagcccg   1320

tgcgacgcgg cgaccaggac gcctgggtgc cccgcgccga cctgacctgc ggctgcctgc   1380

gcctgcagcc aggcaccgac tacctgctgc tgggcagcgc cgtgggcgac cccgacccca   1440

cgcgcctcat cctcgaccgc cacggcctcg cgctgccatg gaggccgcgc tgggcccggc   1500

ccctgaagcg gctgcagcag gaggagcgcg ccggaggctg ccgcggcgtg cgggcaccca   1560

cacccagtcc caggccggag cactagacgt gagatggggc tgcctcgagc accaacaaag   1620

taatttggga gcgactagga gctgagcctt ctacctcgac ggtgcactgc agagagccaa   1680

tcagacgtcg cagagccccg acgacactat gcttgcgccc acgccgagca ggcgtgcgga   1740

acttttagca aaaggcggca agcgggactt ctggtcccaa catttcctcc tttggcctgt   1800

ggcttattcc ccgccagtga tctgtttccc ccaataaagt ctcaaatctt tggg         1854


<210>  9385
<211>  489
<212>  PRT
<213>  Homo sapiens

<400>  9385

Met Pro Val Thr Phe Ala Leu Leu Leu Leu Leu Gly Gln Ala Thr Ala 
1               5                   10                  15


Asp Pro Cys Tyr Asp Pro Gln Gly Arg Pro Gln Phe Cys Leu Pro Pro 
            20                  25                  30


Val Thr Gln Leu Ala Ala Val Ala Ala Ser Cys Pro Gln Ala Cys Ala 
        35                  40                  45


Leu Ser Pro Gly Asn His Leu Gly Ala Arg Glu Thr Cys Asn Gly Ser 
    50                  55                  60


Leu Thr Leu Ala Leu Gly Gly Pro Phe Leu Leu Thr Ser Val Ser Leu 
65                  70                  75                  80


Arg Phe Cys Thr Pro Gly Pro Pro Ala Leu Ile Leu Ser Ala Ala Trp 
                85                  90                  95


Ala Ser Gly Gly Pro Trp Arg Leu Leu Trp His Arg Pro Ala Trp Pro 
            100                 105                 110


Gly Ala Leu Gly Gly Pro Glu Arg Val Thr Phe His Ser Thr Pro Gly 
        115                 120                 125


Pro Lys Ala Thr Val Ala Ala Ser His Leu Arg Val Glu Phe Gly Gly 
    130                 135                 140


Gln Ala Gly Leu Ala Ala Ala Gly Leu Arg Gly Arg Cys Gln Cys His 
145                 150                 155                 160


Gly His Ala Ala Arg Cys Ala Ala Arg Ala Arg Pro Pro Arg Cys His 
                165                 170                 175


Cys Arg His His Thr Thr Gly Pro Gly Cys Glu Ser Cys Arg Pro Ser 
            180                 185                 190


His Arg Asp Trp Pro Trp Arg Pro Ala Thr Pro Arg His Pro His Pro 
        195                 200                 205


Cys Leu Pro Cys Ser Cys Asn Gln His Ala Arg Arg Cys Arg Phe Asn 
    210                 215                 220


Ser Glu Leu Phe Arg Leu Ser Gly Gly Arg Ser Gly Gly Val Cys Glu 
225                 230                 235                 240


Arg Cys Arg His His Thr Ala Gly Arg His Cys His Tyr Cys Gln Pro 
                245                 250                 255


Gly Phe Trp Arg Asp Pro Ser Gln Pro Ile Phe Ser Arg Arg Ala Cys 
            260                 265                 270


Arg Ala Cys Gln Cys His Pro Ile Gly Ala Thr Gly Gly Thr Cys Asn 
        275                 280                 285


Gln Thr Ser Gly Gln Cys Thr Cys Lys Leu Gly Val Thr Gly Leu Thr 
    290                 295                 300


Cys Asn Arg Cys Gly Pro Gly Tyr Gln Gln Ser Arg Ser Pro Arg Met 
305                 310                 315                 320


Pro Cys Gln Arg Ile Pro Glu Ala Thr Thr Thr Leu Ala Thr Thr Pro 
                325                 330                 335


Gly Ala Tyr Ser Ser Asp Pro Gln Cys Gln Asn Tyr Cys Asn Met Ser 
            340                 345                 350


Asp Thr Arg Val His Met Ser Leu Arg Arg Tyr Cys Gln Gln Asp His 
        355                 360                 365


Val Leu Arg Ala Gln Val Leu Ala Ser Glu Ala Ala Gly Pro Ala Trp 
    370                 375                 380


Gln Arg Leu Ala Val Arg Val Leu Ala Val Tyr Lys Gln Arg Ala Gln 
385                 390                 395                 400


Pro Val Arg Arg Gly Asp Gln Asp Ala Trp Val Pro Arg Ala Asp Leu 
                405                 410                 415


Thr Cys Gly Cys Leu Arg Leu Gln Pro Gly Thr Asp Tyr Leu Leu Leu 
            420                 425                 430


Gly Ser Ala Val Gly Asp Pro Asp Pro Thr Arg Leu Ile Leu Asp Arg 
        435                 440                 445


His Gly Leu Ala Leu Pro Trp Arg Pro Arg Trp Ala Arg Pro Leu Lys 
    450                 455                 460


Arg Leu Gln Gln Glu Glu Arg Ala Gly Gly Cys Arg Gly Val Arg Ala 
465                 470                 475                 480


Pro Thr Pro Ser Pro Arg Pro Glu His 
                485


<210>  9386
<211>  1257
<212>  DNA
<213>  Homo sapiens

<400>  9386
tctgctctga gcccccgccc agcccagaaa ccccactagc ctggggcctg agaacagcca     60

cgccactccc tcctgagagc ccaccgcgcc acagcttgga ggaagagcct gcggggaact    120

ggctgcagga cgctctcttc ttgagtgcag cctgctcctg caaccagcac gcccgacgct    180

gccggttcaa ctctgagctg ttcagactgt cgggcggccg gagtgggggt gtttgtgagc    240

ggtgccgcca ccacacagct gggcggcact gccactactg ccaacctggg ttctggaggg    300

accctagcca gcctatcttc agccgcaggg cctgcagagc ctgccagtgc caccctattg    360

gggcaacagg aggaacctgc aaccagacca gtgggcagtg cacctgcaag ttaggggtca    420

caggcctgac ctgcaaccgc tgtggccctg gctaccagca gagccgctcc cccaggatgc    480

cctgccagcg aattccagag gcaacaacca cccttgccac tactcctggt gcttatagct    540

ctgaccctca gtgtcaaaac tactgcaata tgtcggacac cagggtacac atgagccttc    600

ggaggtactg ccagcaggac catgttctcc gcgcgcaggt gctagcgtcc gaggcggcgg    660

gcccggcatg gcagcggctg gccgtgcgcg tgctggccgt ttacaagcag cgggcgcagc    720

ccgtgcgacg cggcgaccag gacgcctggg tgccccgcgc cgacctgacc tgcggctgcc    780

tgcgcctgca gccaggcacc gactacctgc tgctgggcag cgccgtgggc gaccccgacc    840

ccacgcgcct catcctcgac cgccacggcc tcgcgctgcc atggaggccg cgctgggccc    900

ggcccctgaa gcggctgcag caggaggagc gcgccggagg ctgccgcggc gtgcgggcac    960

ccacacccag tcccaggccg gagcactaga cgtgagatgg ggctgcctcg agcaccaaca   1020

aagtaatttg ggagcgacta ggagctgagc cttctacctc gacggtgcac tgcagagagc   1080

caatcagacg tcgcagagcc ccgacgacac tatgcttgcg cccacgccga gcaggcgtgc   1140

ggaactttta gcaaaaggcg gcaagcggga cttctggtcc caacatttcc tcctttggcc   1200

tgtggcttat tccccgccag tgatctgttt cccccaataa agtctcaaat ctttggg      1257


<210>  9387
<211>  170
<212>  PRT
<213>  Homo sapiens

<400>  9387

Met Pro Cys Gln Arg Ile Pro Glu Ala Thr Thr Thr Leu Ala Thr Thr 
1               5                   10                  15


Pro Gly Ala Tyr Ser Ser Asp Pro Gln Cys Gln Asn Tyr Cys Asn Met 
            20                  25                  30


Ser Asp Thr Arg Val His Met Ser Leu Arg Arg Tyr Cys Gln Gln Asp 
        35                  40                  45


His Val Leu Arg Ala Gln Val Leu Ala Ser Glu Ala Ala Gly Pro Ala 
    50                  55                  60


Trp Gln Arg Leu Ala Val Arg Val Leu Ala Val Tyr Lys Gln Arg Ala 
65                  70                  75                  80


Gln Pro Val Arg Arg Gly Asp Gln Asp Ala Trp Val Pro Arg Ala Asp 
                85                  90                  95


Leu Thr Cys Gly Cys Leu Arg Leu Gln Pro Gly Thr Asp Tyr Leu Leu 
            100                 105                 110


Leu Gly Ser Ala Val Gly Asp Pro Asp Pro Thr Arg Leu Ile Leu Asp 
        115                 120                 125


Arg His Gly Leu Ala Leu Pro Trp Arg Pro Arg Trp Ala Arg Pro Leu 
    130                 135                 140


Lys Arg Leu Gln Gln Glu Glu Arg Ala Gly Gly Cys Arg Gly Val Arg 
145                 150                 155                 160


Ala Pro Thr Pro Ser Pro Arg Pro Glu His 
                165                 170


<210>  9388
<211>  1490
<212>  DNA
<213>  Homo sapiens

<400>  9388
ggggaactgg ctgcaggacg ctctcttctt gagtgcagcc tgctcctgca accagcacgc     60

ccgacgctgc cggttcaact ctgagctgtt cagactgtcg ggcggccgga gtgggggtgt    120

ttgtgagcgg tgccgccacc acacagctgg gcggcactgc cactactgcc aacctgggtt    180

ctggagggac cctagccagc ctatcttcag ccgcagggcc tgcagagcct gccagtgcca    240

ccctattggg gcaacaggag gaacctgcaa ccagaccagt gggcagtgca cctgcaagtt    300

aggggtcaca ggcctgacct gcaaccgctg tggccctggc taccagcaga gccgctcccc    360

caggatgccc tgccagcgaa ttccagaggc aacaaccacc cttgccacta ctcctggtgc    420

ttatagctct gaccctcagt gtcaaaacta ctgcaatatg tcggacacca gggtacacat    480

gagccttcgg aggtactgcc agcaggacca tggtgagtgc tggggagaca gacagctgaa    540

ggctacacag ctggttctga tgactgcttc taagccaccc cctttctggc cttccacttt    600

ctcatcttaa atgggaagga gtgttggatt ccaaacccct tcctgatcta gaaattgatg    660

gggcagaaga caaatgggga ggggagtggg gagggggcat tcactacctt cctgtgtctc    720

ctctttcccc atgttcttcg gcttacagag tttcatcatc tccttcagcc tgacatctct    780

gagggatgga agagataggg gaactggttg agtggaatga actcttgccc tgtcctccct    840

atctcagaga ccctttctgc ttcccttcat ggtcccagat atttgagcct tagccccact    900

tcccataaag acttgtccca cggttcccta atccccagtc cacacctgct ccatgacctt    960

ggggtctatg acctcaggct attcagctct cttaagacac tcaggagttc ggcccagcca   1020

acaaatctag accaacgcca gctatttctc tcaatgtata ggaccgcaga cttctccctc   1080

aggaacctca tctggtcact agtgttctag gccttcacag gtggaaagat tttccccacc   1140

ttccacaggg atctcctgcc ccgcagaccc agctggctag tcagagtccc acccagcctc   1200

tcagaaagtg catttttctg gccgggcgcg gtggctcatg ctaataatcc cagcactttg   1260

tgggggccga ggtgggcgga tcacttgagg tcaggagttc gagaccagcc tggccaacat   1320

ggtgaaactc catctctact aaaaatacaa aaattagcca ggcgtggtgg caggatcctg   1380

taaacccagc tgaggcacaa gaatcacttc aacctgggag gcagaggctg cagtgagttg   1440

agatcacacc actgcactcc agactgggca atagagtaag attccgtctc              1490


<210>  9389
<211>  81
<212>  PRT
<213>  Homo sapiens

<400>  9389

Met Pro Cys Gln Arg Ile Pro Glu Ala Thr Thr Thr Leu Ala Thr Thr 
1               5                   10                  15


Pro Gly Ala Tyr Ser Ser Asp Pro Gln Cys Gln Asn Tyr Cys Asn Met 
            20                  25                  30


Ser Asp Thr Arg Val His Met Ser Leu Arg Arg Tyr Cys Gln Gln Asp 
        35                  40                  45


His Gly Glu Cys Trp Gly Asp Arg Gln Leu Lys Ala Thr Gln Leu Val 
    50                  55                  60


Leu Met Thr Ala Ser Lys Pro Pro Pro Phe Trp Pro Ser Thr Phe Ser 
65                  70                  75                  80


Ser 



<210>  9390
<211>  2416
<212>  DNA
<213>  Homo sapiens

<400>  9390
cagccacgcc actccctcct gagagcccac cgcgccacag cttggaggaa gagcctgcgg     60

ggaactggct gcaggacgct ctcttcttga gtgcaggtgc tggctctgct gtgaccatgc    120

ccgtgacctt tgccctcctg ctcctcctgg gccaggccac tgcggaccca tgctacgatc    180

cacagggccg cccccaattc tgcctcccgc cagtgacaca gctggctgcc gtggcggcct    240

cctgccctca ggcctgtgcc ctgtccccag gaaaccacct tggcgccagg gaaacctgca    300

atggcagcct gactttggcc ctgggtggcc ccttcctcct gacatctgtc agcttgcgct    360

tctgtacccc aggaccccca gccctcatcc tgtctgctgc ctgggcctca gggggtccct    420

ggaggctgct gtggcacagg cccgcctggc ctggggcctt agggggccct gaaagggtga    480

ccttccactc cacaccaggt cctaaggcca ctgtggcggc cagccacctc cgtgtggagt    540

ttgggggcca ggccgggcta gcggcagctg ggctgagagg ccgctgccag tgtcatggcc    600

acgctgcccg ctgtgccgcc cgtgcccggc ccccccgctg ccactgccgc caccatacca    660

ctggcccggg gtgcgagagc tgccgcccgt cccatcgaga ctggccctgg cggcctgcca    720

cgccccggca cccccaccct tgcctaccct gctcctgcaa ccagcacgcc cgacgctgcc    780

ggttcaactc tgagctgttc agactgtcgg gcggccggag tgggggtgtt tgtgagcggt    840

gccgccacca cacagctggg cggcactgcc actactgcca acctgggttc tggagggacc    900

ctagccagcc tatcttcagc cgcagggcct gcagagcctg ccagtgccac cctattgggg    960

caacaggagg aacctgcaac cagaccagtg ggcagtgcac ctgcaagtta ggggtcacag   1020

gcctgacctg caaccgctgt ggccctggct accagcagag ccgctccccc aggatgccct   1080

gccagcgaat tccagaggca acaaccaccc ttgccactac tcctggtgct tatagctctg   1140

gtaagacagt ctggcacgga ggtccctgag tggcaagtgg gaatgaggat gggctgactg   1200

ggtccccaga tggggataca tgggtcaccc attgagccca gtcccaaagg tttgggtacc   1260

ccagctggcc atcaagatgg aacggaggga tgggcagggg cagaaggctg tggtctaggc   1320

cccaggagcc cactgcagac agcctgaccc tccccagacc ctcagtgtca aaactactgc   1380

aatatgtcgg acaccagggt acacatgagc cttcggaggt actgccagca ggaccatggt   1440

gagtgctggg gagacagaca gctgaaggct acacagctgg ttctgatgac tgcttctaag   1500

ccaccccctt tctggccttc cactttctca tcttaaatgg gaaggagtgt tggattccaa   1560

accccttcct gatctagaaa ttgatggggc agaagacaaa tggggagggg agtggggagg   1620

gggcattcac taccttcctg tgtctcctct ttccccatgt tcttcggctt acagagtttc   1680

atcatctcct tcagcctgac atctctgagg gatggaagag ataggggaac tggttgagtg   1740

gaatgaactc ttgccctgtc ctccctatct cagagaccct ttctgcttcc cttcatggtc   1800

ccagatattt gagccttagc cccacttccc ataaagactt gtcccacggt tccctaatcc   1860

ccagtccaca cctgctccat gaccttgggg tctatgacct caggctattc agctctctta   1920

agacactcag gagttcggcc cagccaacaa atctagacca acgccagcta tttctctcaa   1980

tgtataggac cgcagacttc tccctcagga acctcatctg gtcactagtg ttctaggcct   2040

tcacaggtgg aaagattttc cccaccttcc acagggatct cctgccccgc agacccagct   2100

ggctagtcag agtcccaccc agcctctcag aaagtgcatt tttctggccg ggcgcggtgg   2160

ctcatgctaa taatcccagc actttgtggg ggccgaggtg ggcggatcac ttgaggtcag   2220

gagttcgaga ccagcctggc caacatggtg aaactccatc tctactaaaa atacaaaaat   2280

tagccaggcg tggtggcagg atcctgtaaa cccagctgag gcacaagaat cacttcaacc   2340

tgggaggcag aggctgcagt gagttgagat cacaccactg cactccagac tgggcaatag   2400

agtaagattc cgtctc                                                   2416


<210>  9391
<211>  350
<212>  PRT
<213>  Homo sapiens

<400>  9391

Met Pro Val Thr Phe Ala Leu Leu Leu Leu Leu Gly Gln Ala Thr Ala 
1               5                   10                  15


Asp Pro Cys Tyr Asp Pro Gln Gly Arg Pro Gln Phe Cys Leu Pro Pro 
            20                  25                  30


Val Thr Gln Leu Ala Ala Val Ala Ala Ser Cys Pro Gln Ala Cys Ala 
        35                  40                  45


Leu Ser Pro Gly Asn His Leu Gly Ala Arg Glu Thr Cys Asn Gly Ser 
    50                  55                  60


Leu Thr Leu Ala Leu Gly Gly Pro Phe Leu Leu Thr Ser Val Ser Leu 
65                  70                  75                  80


Arg Phe Cys Thr Pro Gly Pro Pro Ala Leu Ile Leu Ser Ala Ala Trp 
                85                  90                  95


Ala Ser Gly Gly Pro Trp Arg Leu Leu Trp His Arg Pro Ala Trp Pro 
            100                 105                 110


Gly Ala Leu Gly Gly Pro Glu Arg Val Thr Phe His Ser Thr Pro Gly 
        115                 120                 125


Pro Lys Ala Thr Val Ala Ala Ser His Leu Arg Val Glu Phe Gly Gly 
    130                 135                 140


Gln Ala Gly Leu Ala Ala Ala Gly Leu Arg Gly Arg Cys Gln Cys His 
145                 150                 155                 160


Gly His Ala Ala Arg Cys Ala Ala Arg Ala Arg Pro Pro Arg Cys His 
                165                 170                 175


Cys Arg His His Thr Thr Gly Pro Gly Cys Glu Ser Cys Arg Pro Ser 
            180                 185                 190


His Arg Asp Trp Pro Trp Arg Pro Ala Thr Pro Arg His Pro His Pro 
        195                 200                 205


Cys Leu Pro Cys Ser Cys Asn Gln His Ala Arg Arg Cys Arg Phe Asn 
    210                 215                 220


Ser Glu Leu Phe Arg Leu Ser Gly Gly Arg Ser Gly Gly Val Cys Glu 
225                 230                 235                 240


Arg Cys Arg His His Thr Ala Gly Arg His Cys His Tyr Cys Gln Pro 
                245                 250                 255


Gly Phe Trp Arg Asp Pro Ser Gln Pro Ile Phe Ser Arg Arg Ala Cys 
            260                 265                 270


Arg Ala Cys Gln Cys His Pro Ile Gly Ala Thr Gly Gly Thr Cys Asn 
        275                 280                 285


Gln Thr Ser Gly Gln Cys Thr Cys Lys Leu Gly Val Thr Gly Leu Thr 
    290                 295                 300


Cys Asn Arg Cys Gly Pro Gly Tyr Gln Gln Ser Arg Ser Pro Arg Met 
305                 310                 315                 320


Pro Cys Gln Arg Ile Pro Glu Ala Thr Thr Thr Leu Ala Thr Thr Pro 
                325                 330                 335


Gly Ala Tyr Ser Ser Gly Lys Thr Val Trp His Gly Gly Pro 
            340                 345                 350


<210>  9392
<211>  855
<212>  DNA
<213>  Homo sapiens

<400>  9392
cccatacagg gggagctcag gcagggtcag cggagggacc tgcgcctgaa tcccgaagtt     60

ccactctgac tcacacagcc tgggccccca gctctgacat gccccctctg atggggggcg    120

tctcagcccc attccatcct cctgcagctg atgcacctcc cagctttcgg agtgactccc    180

ttctttcaaa tccgatgtcc ctgtcctgct cctgccaaat ctggccccct ccaacgtggt    240

acctaagggt ccagagtcga gggtcgcctt tgctgtgccc tcgcaccccc tgggggcggg    300

cctggggcag tgggtcccaa gcctgtcagg attgggccca cgctacacca cgataaacgc    360

tggggccagg ccactgcgga cccatgctac gatccacagg gccgccccca attctgcctc    420

ccgccagtga cacagctggc tgccgtggcg gcctcctgcc ctcaggcctg tgccctgtcc    480

ccaggaaacc accttggcgc cagggaaacc tgcaatggca gcctgacttt ggccctgggt    540

ggccccttcc tcctgacatc tgtcagcttg cgcttctgta ccccaggacc cccagccctc    600

atcctgtctg ctgcctgggc ctcagggggt ccctggaggc tgctgtggca caggcccgcc    660

tggcctgggg ccttaggggg ccctgaaagg gtgaccttcc actccacacc aggtcctaag    720

gccactgtgg cggccagcca cctccgtgtg gagtttgggg gccaggccgg gctagcggca    780

gctgggctga gaggccgctg ccagtgtcat ggccacgctg cccgctgtgc cgcccgtgcc    840

cggccccccc gctgc                                                     855


<210>  9393
<211>  100
<212>  PRT
<213>  Homo sapiens

<400>  9393

Met Leu Arg Ser Thr Gly Pro Pro Pro Ile Leu Pro Pro Ala Ser Asp 
1               5                   10                  15


Thr Ala Gly Cys Arg Gly Gly Leu Leu Pro Ser Gly Leu Cys Pro Val 
            20                  25                  30


Pro Arg Lys Pro Pro Trp Arg Gln Gly Asn Leu Gln Trp Gln Pro Asp 
        35                  40                  45


Phe Gly Pro Gly Trp Pro Leu Pro Pro Asp Ile Cys Gln Leu Ala Leu 
    50                  55                  60


Leu Tyr Pro Arg Thr Pro Ser Pro His Pro Val Cys Cys Leu Gly Leu 
65                  70                  75                  80


Arg Gly Ser Leu Glu Ala Ala Val Ala Gln Ala Arg Leu Ala Trp Gly 
                85                  90                  95


Leu Arg Gly Pro 
            100


<210>  9394
<211>  2418
<212>  DNA
<213>  Homo sapiens

<400>  9394
atcccactcc acccctgccc actggctcag ccccgccttg tggtggccgc catcgcgatc     60

gggcaggggc tgacctttgg gagacaatcg ctgttggaaa ctttgctcag cccctgcctc    120

tggctgcgtg accccaagcc agcccctcct cctcctctct ggaacctttt gtcagctgtg    180

ggttcaccga gccttaagcc gtcaagggat tctgggccac ccgcccttcc ttctccacct    240

tctacttcgt ctttgccatt tttgtggtgt ccaccatctt tcactgccac cagcacctgg    300

ctctggtgcc tgcgccctgg gcatactcag cccgtgtggt cctggccccc agacacctgc    360

cccgggagga cctgttcact atcaactcca agggccgcct ggggaaccag atgggcgagt    420

acgccacgct gtacgccctg gccaagatga acgggcggcc cgccttcatc ccggcccaga    480

tgcacagcac cctggccccc atcttcagaa tcaccctgcc ggtgctgcac agcgccacgg    540

ccagcaggat cccctggcag aactaccacc tgaacgactg gatggaggag gagtaccgcc    600

acatcccggg gcgctgtgtc cgcctcacgg gctacccctg ctcctggacc ttctaccacc    660

acctccgcca ggagatcctc caggagttca ccctgcacga ccacgtgcgc gaggaggccc    720

agaagttcct gcggggcctg caggccaagt gggcagggca ggcgaccttc gtgggggtcc    780

acgtgcgccg gggggactat gtccgtgtca tgccgcgcgt atggaagggg gtgctggccg    840

accggctacc tgcagcgggc cctggactgg ttccgggcct gctgccgcct cccggtcttt    900

gtggtcacca gcgatgacat ggcctggtgc cgggagagca tcaacagctc ccttggggac    960

gtggtgttcg ctggcaatgg cctccagggc tcacctgcca aggacttcgc actgctcaca   1020

cagtgcaacc acaccatcat caccgtgggc accttcgggg tctgggccgc gtacctcgcg   1080

ggcggggaca ctgtctacct ggccaacttc accctgccca actccccttt caacgtggtc   1140

tttaggccgt aagcggcctt cctgccagag tgggtgggcc ttgcggctga ccttggacag   1200

gctggacaga acggcctcta gccagccctg catgtgcctg gtcctcatcc tgtgacccga   1260

ggggcagtga gtggggcgtg cggggcatgg actcacggtc cctcatgcag tttggatcca   1320

ggcttatcta cttcatagct gagtgagttt ggacaactga ctcaacctct gtgccttagt   1380

atgtcaacca caaaatgcac aaaccacaga actaaacacc agtagcagct ggtgggagct   1440

gagcaaattc gcttagagcc agtgccttgt gaccgtgtgg gaggtgtcgg ctgctcacat   1500

gtatgcagca cgtcaggaac actggcattg ctttccaatg gaaacgcagt tttgccctct   1560

ccttcctggc agcactggta gcacagagcc cagatatttt gcactcacgt cccaggacga   1620

agccatccct gccctgaagg ataggggaac tcgattttct gggcaactag gaattttggc   1680

tttggagtta gtgggcctta tcacaaaaga atgtgaggga agggccgggt gcggtggcac   1740

gcctgtaatc ccagcccttt gggaagccaa ggctggtgga tcacttgagg tcaggagttc   1800

gagaccagcc tggccaacat ggcgaaaccc agtctctact aaaaatacaa aaagccaggc   1860

acggtggtgc gtgcccctaa tcccagctac tccggaggct gaagcaggag gatagcttga   1920

attgggaagc agaggttgca gtaaaccgag atcataccac tgcactccag cctgggccac   1980

agagcgagac tccatcgcaa aaaaaaaaaa aaaaatagaa ttccagggaa gacaggattt   2040

gcagggacac acctatgagg agggattccc ctgcgatgga caggggaggg gtttaggtgc   2100

aggtagcacc ctgggcgcag ggaagaaggc gtcacagtga gggcagaaaa gacactcctc   2160

agatcctgga agcagcaacc tgacccccag gggccactaa gaccaaatca tggccatctc   2220

agcagcagcg tgtgtgacag ttactggaaa aagatacctc acacctggca ctgcctaacc   2280

cccgagaacc taatgccact ctgagaaagc tcagtacggg tgcaagttgg attaagtaat   2340

tgcagtgcga gttttcctgt gttttattgg tgtaatgctc cttttggaca ttaaaaaaac   2400

ttgacatata caatgatc                                                 2418


<210>  9395
<211>  168
<212>  PRT
<213>  Homo sapiens

<400>  9395

Met Gly Glu Tyr Ala Thr Leu Tyr Ala Leu Ala Lys Met Asn Gly Arg 
1               5                   10                  15


Pro Ala Phe Ile Pro Ala Gln Met His Ser Thr Leu Ala Pro Ile Phe 
            20                  25                  30


Arg Ile Thr Leu Pro Val Leu His Ser Ala Thr Ala Ser Arg Ile Pro 
        35                  40                  45


Trp Gln Asn Tyr His Leu Asn Asp Trp Met Glu Glu Glu Tyr Arg His 
    50                  55                  60


Ile Pro Gly Arg Cys Val Arg Leu Thr Gly Tyr Pro Cys Ser Trp Thr 
65                  70                  75                  80


Phe Tyr His His Leu Arg Gln Glu Ile Leu Gln Glu Phe Thr Leu His 
                85                  90                  95


Asp His Val Arg Glu Glu Ala Gln Lys Phe Leu Arg Gly Leu Gln Ala 
            100                 105                 110


Lys Trp Ala Gly Gln Ala Thr Phe Val Gly Val His Val Arg Arg Gly 
        115                 120                 125


Asp Tyr Val Arg Val Met Pro Arg Val Trp Lys Gly Val Leu Ala Asp 
    130                 135                 140


Arg Leu Pro Ala Ala Gly Pro Gly Leu Val Pro Gly Leu Leu Pro Pro 
145                 150                 155                 160


Pro Gly Leu Cys Gly His Gln Arg 
                165


<210>  9396
<211>  796
<212>  DNA
<213>  Homo sapiens

<400>  9396
gtcgctgaat cacagggaaa caggctggag tgcaatggtg taatctcagt ttatgcagcc     60

tccgcctccc aggttcaagc gattctcctg cctcagcctc ccgagtagct aggattacag    120

gtgcgtgcca ccacgcccag ctaattttta tatgtttagt ggaaatggag tttcaccatg    180

ttggtcaggc tggtctcaaa ctcctgacct catgatccgc cttcctcggc ctcccaaagt    240

gctgggatta caggtgttag ccactgcgcc cggccctaga gctcactgtt ttctagttag    300

tccatctgga agtggagcct ttttccagtt tgcacaaatg tgccatattg gcttgtagct    360

ggcatgcatc caagtccata ggtcctgcct cttcaatcct ggctttctag ggcctgggat    420

gatcattgct agaactgaga gaccagcctg gctcagtgaa cttcagggcg ttccgttcat    480

tctttcagta aatgtttgca gcacatgtgt tacatgtcag gcagtgaaac cccccacagc    540

agccttccct ctcagaggat acatttgtaa ccattacaca gtcatcaaag gaataatttt    600

ttttaatcac cagtgtgcat acagtcatgg agttgggtat tcccagctac cagggaggct    660

gaggtgggag gattgcttga tgccaggagt tagggaatat agtgcaccgt gattggactt    720

gcgaatagcc actgcactgc ggcctggacg acgtagtgat accctgactc ttataaataa    780

ataaatgaat aaacac                                                    796


<210>  9397
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  9397

Met Ile Ile Ala Arg Thr Glu Arg Pro Ala Trp Leu Ser Glu Leu Gln 
1               5                   10                  15


Gly Val Pro Phe Ile Leu Ser Val Asn Val Cys Ser Thr Cys Val Thr 
            20                  25                  30


Cys Gln Ala Val Lys Pro Pro Thr Ala Ala Phe Pro Leu Arg Gly Tyr 
        35                  40                  45


Ile Cys Asn His Tyr Thr Val Ile Lys Gly Ile Ile Phe Phe Asn His 
    50                  55                  60


Gln Cys Ala Tyr Ser His Gly Val Gly Tyr Ser Gln Leu Pro Gly Arg 
65                  70                  75                  80


Leu Arg Trp Glu Asp Cys Leu Met Pro Gly Val Arg Glu Tyr Ser Ala 
                85                  90                  95


Pro 



<210>  9398
<211>  845
<212>  DNA
<213>  Homo sapiens

<400>  9398
gtcgctgaat cacagggaaa caggctggag tgcaatggtg taatctcagt ttatgcagcc     60

tccgcctccc aggttcaagc gattctcctg cctcagcctc ccgagtagct aggattacag    120

gtgcgtgcca ccacgcccag ctaattttta tatgtttagt ggaaatggag tttcaccatg    180

ttggtcaggc tggtctcaaa ctcctgacct catgatccgc cttcctcggc ctcccaaagt    240

gctgggatta caggtgttag ccactgcgcc cggccctaga gctcactgtt ttctagttag    300

tccatctgga agtggagcct ttttccagtt tgcacaaatg tgccatattg gcttgtagct    360

ggcatgcatc caagtccata ggtcctgcct cttcaatcct ggctttctag ggcctgggat    420

gatcattgct agaactgaga gaccagcctg gctcagtgaa cttcagggcg ttccgttcat    480

tctttcagta aatgtttgca gcacatgtgt tacatgtcag gcagtgaaac cccccacagc    540

agccttccct ctcagaggat acatttgtaa ccattacaca gtcatcaaag gaataatttt    600

ttttaatcac cagtgtgcat acagtcatgg agttgggtat tcccagctac cagggaggct    660

gaggtgggag gattgcttga tgccaggagt tagggaatat agtgcaccgt gattggactt    720

gcgaatagcc actgcactgc ggcctggacg acgtagtgat accctgactc ttataaataa    780

ataaatgaat aaacacaatt atgactttgc ggatgggaga aaaggttctc tgagagcgta    840

ttaca                                                                845


<210>  9399
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  9399

Met Ile Ile Ala Arg Thr Glu Arg Pro Ala Trp Leu Ser Glu Leu Gln 
1               5                   10                  15


Gly Val Pro Phe Ile Leu Ser Val Asn Val Cys Ser Thr Cys Val Thr 
            20                  25                  30


Cys Gln Ala Val Lys Pro Pro Thr Ala Ala Phe Pro Leu Arg Gly Tyr 
        35                  40                  45


Ile Cys Asn His Tyr Thr Val Ile Lys Gly Ile Ile Phe Phe Asn His 
    50                  55                  60


Gln Cys Ala Tyr Ser His Gly Val Gly Tyr Ser Gln Leu Pro Gly Arg 
65                  70                  75                  80


Leu Arg Trp Glu Asp Cys Leu Met Pro Gly Val Arg Glu Tyr Ser Ala 
                85                  90                  95


Pro 



<210>  9400
<211>  1790
<212>  DNA
<213>  Homo sapiens

<400>  9400
agtcaccgat gctggaaggg tttctttggc cctgagtgaa gagagaccca gagggaacac     60

tgaggtgcct gcccaaccac tctgtcccgg tttccttcag caggaccagc catgctggtc    120

gttcagatgc ctttctcctt tcccatggcc cacttcatcc tctttgtctt tacggtttcc    180

actatatttc acgttcagca gcggctagcg aagattcaag ccatgtggga gttaccggtg    240

cagataccag tgctagcctc aacatcaaag gcactgggac ccagccagct cagggggatg    300

tggacgatca atgcaatagg ccgcctgggg aaccagatgg gcgagtacgc cacactgtac    360

gccctggcca agatgaacgg gcggcccgcc ttcatcccgg cccagatgca cagcaccctg    420

gcccccatct tcagaatcac cctgccggtg ctgcacagcg ccacggccag caggatcccc    480

tggcagaact accacctgaa cgactggatg gaggaggaat accgccacat cccgggggag    540

tacgtccgct tcaccggcta cccctgctcc tggaccttct accaccacct ccgccaggag    600

atcctccagg agttcaccct gcacgaccac gtgcgggagg aggcccagaa gttcctgcgg    660

ggcctgcagg tgaacgggag ccggccgggc acctttgtag gggtccatgt tcgccgaggg    720

gactatgtcc atgtcatgcc aaaagtgtgg aagggggtgg tggccgaccg gcgataccta    780

cagcaggccc tggactggtt ccgagctcgc tacagctccc tcatcttcgt ggtcaccagt    840

aatggcatgg cctggtgtcg ggagaacatt gacacctccc acggtgatgt ggtgtttgct    900

ggcgatggca ttgagggctc acctgccaaa gattttgctc tactcacaca gtgtaaccac    960

accatcatga ccattgggac gttcgggatc tgggccgcat acctcacggg cggagacacc   1020

atctacctgg ccaattacac cctccccgac tcccctttcc tcaaaatctt taagccagag   1080

gcagccttcc tgccggagtg gacagggatt gccgcagacc tgtccccctt actcaagcac   1140

taatgctggc ccattctttg agaccttttc tccttctctg cctccctcaa gatgagtgcc   1200

cgggcatgag aagcacatgg ttccatgagc aggacccatc tctcttctgt gaagatgcgt   1260

tgggctgcaa gtaacagaaa tctcagtgaa cagtggcctg gcgtggtggc tcatgcctgt   1320

aatgcctccc aaagtgctgg gattacaggt gttagccact gcgcccggcc ctagagctca   1380

ctgttttcta gttagtccat ctggaagtgg agcctttttc cagtttgcac aaatgtgcca   1440

tattggcttg tagctggcat gcatccaagt ccataggtcc tgcctcttca atcctggctt   1500

tctagggcct gggatgatca ttgctagaac tgagagacca gcctggctca gtgaacttca   1560

gggcgttccg ttcattcttt cagtaaatgt ttgcagcaca tgtgttacat gtcaggcagt   1620

gaaacccccc acagcagcct tccctctcag aggatacatt tgtaaccatt acacagtcat   1680

caaaggaata atttttttta atcaccatga ttggacttgc gaatagccac tgcactgcgg   1740

cctggacgac gtagtgatac cctgactctt ataaataaat aaatgaataa              1790


<210>  9401
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  9401

Met Ile Ile Ala Arg Thr Glu Arg Pro Ala Trp Leu Ser Glu Leu Gln 
1               5                   10                  15


Gly Val Pro Phe Ile Leu Ser Val Asn Val Cys Ser Thr Cys Val Thr 
            20                  25                  30


Cys Gln Ala Val Lys Pro Pro Thr Ala Ala Phe Pro Leu Arg Gly Tyr 
        35                  40                  45


Ile Cys Asn His Tyr Thr Val Ile Lys Gly Ile Ile Phe Phe Asn His 
    50                  55                  60


His Asp Trp Thr Cys Glu 
65                  70


<210>  9402
<211>  3123
<212>  DNA
<213>  Homo sapiens

<400>  9402
gctggaaggg tttctttggc cctgagtgaa gagagaccca gagggaacac tgaggtgcct     60

gcccaaccac tctgtcccgg tttccttcag caggaccagc catgctggtc gttcagatgc    120

ctttctcctt tcccatggcc cacttcatcc tctttgtctt tacggtttcc actatatttc    180

acgttcagca gcggctagcg aagattcaag ccatgtggga gttaccggtg cagataccag    240

tgctagcctc aacatcaaag gcactgggac ccagccagct cagggggatg tggacgatca    300

atgcaatagg ccgcctgggg aaccagatgg gcgagtacgc cacactgtac gccctggcca    360

agatgaacgg gcggcccgcc ttcatcccgg cccagatgca cagcaccctg gcccccatct    420

tcagaatcac cctgccggtg ctgcacagcg ccacggccag caggatcccc tggcagaact    480

accacctgaa cgactggatg gaggaggaat accgccacat cccgggggag tacgtccgct    540

tcaccggcta cccctgctcc tggaccttct accaccacct ccgccaggag atcctccagg    600

agttcaccct gcacgaccac gtgcgggagg aggcccagaa gttcctgcgg ggcctgcagg    660

tgaacgggag ccggccgggc acctttgtag gggtccatgt tcgccgaggg gactatgtcc    720

atgtcatgcc aaaagtgtgg aagggggtgg tggccgaccg gcgataccta cagcaggccc    780

tggactggtt ccgagctcgc tacagctccc tcatcttcgt ggtcaccagt aatggcatgg    840

cctggtgtcg ggagaacatt gacacctccc acggtgatgt ggtgtttgct ggcgatggca    900

ttgagggctc acctgccaaa gattttgctc tactcacaca gtgtaaccac accatcatga    960

ccattgggac gttcgggatc tgggccgcat acctcacggg cggagacacc atctacctgg   1020

ccaattacac cctccccgac tcccctttcc tcaaaatctt taagccagag gcagccttcc   1080

tgccggagtg gacagggatt gccgcagacc tgtccccctt actcaagcac taatgctggc   1140

ccattctttg agaccttttc tccttctctg cctccctcaa gatgagtgcc cgggcatgag   1200

aagcacatgg ttccatgagc aggacccatc tctcttctgt gaagatgcgt tgggctgcaa   1260

gtaacagaaa tctcagtgaa cagtggcctg gcgtggtggc tcatgcctgt aatgctcgca   1320

ctttgtgagg ccagggtggg tggatcactt gaggtcagga gttcaagact agcctggcca   1380

acatggtgaa accccatctc gactaaaaat acaaaaatta gccaggcgtg gtggtgcaca   1440

cctgtaatcc cagctactcg ggaggctgag gcaagagaat cacttgaacc caggaggcgg   1500

aggttgcagt gagccaagat ggtgccgctg cactccagtc tgggtgacac agcaagactc   1560

catctcaaaa aaaaaaaaaa aaaaaagaaa agaaaaagaa atgaatgggt tcaaagacca   1620

taatcatgca tatcacataa gaccagaagt ggcccaggtc cagggtcagt taatttagcg   1680

gctccacaaa gtcatcagtc acctgagctc catccatctt cacatgctgt gctaccattt   1740

cttagctgta tcatcccatg gtcccaaaag ggctgctaca catccagcca tcacatgcag   1800

ataattcctt tcaaaaacag cagaaagagg ctcgttcttg tcttggtccc ttttgaagaa   1860

tgaatgaaac cttcctaagc cttccagcaa tttcccccca actccgatgg gtaggaattg   1920

tcacataccc atgtgacccg ataggaggca aaagaaatga gacttctggg attagtttag   1980

cctcagattc tgcagctgag aagttgatca gccacctctg aaggacatgc agcttgcaga   2040

aaattagggt ggtgttacca aggtgaaaag gggaaatggc tttagagtag acaacagaga   2100

tgccctgagg ggttgtgtag gttgttcact gcaggaagtc ccctggttaa gaaggcaagt   2160

ggggtttaaa cagacccaca gtctactcat caaaccaggt gtccttggca ttgtgtccac   2220

ccagagagct cactgttttc ttttcttttt cttttctttt tttttttttt tttgagatgg   2280

agtcttgctg catcccccag gctggagtgc agtggcatga tcttggctca ctgcagcctc   2340

cgcctcccag gttcaagcga ttctcctgcc tcagcctccc gagtagctag gattacaggt   2400

gcgtgccacc acgcccagct aatttttata tgtttagtgg aaatggagtt tcaccatgtt   2460

ggtcaggctg gtctcaaact cctgacctca tgatccgcct tcctcggcct cccaaagtgc   2520

tgggattaca ggtgttagcc actgcgcccg gccctagagc tcactgtttt ctagttagtc   2580

catctggaag tggagccttt ttccagtttg cacaaatgtg ccatattggc ttgtagctgg   2640

catgcatcca agtccatagg tcctgcctct tcaatcctgg ctttctaggg cctgggatga   2700

tcattgctag aactgagaga ccagcctggc tcagtgaact tcagggcgtt ccgttcattc   2760

tttcagtaaa tgtttgcagc acatgtgtta catgtcaggc agtgaaaccc cccacagcag   2820

ccttccctct cagaggatac atttgtaacc attacacagt catcaaagga ataatttttt   2880

ttaatcacca gtgtgcatac agtcatggag ttgggtattc ccagctacca gggaggctga   2940

ggtgggagga ttgcttgatg ccaggagtta gggaatatag tgcaccgtga ttggacttgc   3000

gaatagccac tgcactgcgg cctggacgac gtagtgatac cctgactctt ataaataaat   3060

aaatgaataa acacaattat gactttgcgg atgggagaaa aggttctctg agagcgtatt   3120

aca                                                                 3123


<210>  9403
<211>  343
<212>  PRT
<213>  Homo sapiens

<400>  9403

Met Leu Val Val Gln Met Pro Phe Ser Phe Pro Met Ala His Phe Ile 
1               5                   10                  15


Leu Phe Val Phe Thr Val Ser Thr Ile Phe His Val Gln Gln Arg Leu 
            20                  25                  30


Ala Lys Ile Gln Ala Met Trp Glu Leu Pro Val Gln Ile Pro Val Leu 
        35                  40                  45


Ala Ser Thr Ser Lys Ala Leu Gly Pro Ser Gln Leu Arg Gly Met Trp 
    50                  55                  60


Thr Ile Asn Ala Ile Gly Arg Leu Gly Asn Gln Met Gly Glu Tyr Ala 
65                  70                  75                  80


Thr Leu Tyr Ala Leu Ala Lys Met Asn Gly Arg Pro Ala Phe Ile Pro 
                85                  90                  95


Ala Gln Met His Ser Thr Leu Ala Pro Ile Phe Arg Ile Thr Leu Pro 
            100                 105                 110


Val Leu His Ser Ala Thr Ala Ser Arg Ile Pro Trp Gln Asn Tyr His 
        115                 120                 125


Leu Asn Asp Trp Met Glu Glu Glu Tyr Arg His Ile Pro Gly Glu Tyr 
    130                 135                 140


Val Arg Phe Thr Gly Tyr Pro Cys Ser Trp Thr Phe Tyr His His Leu 
145                 150                 155                 160


Arg Gln Glu Ile Leu Gln Glu Phe Thr Leu His Asp His Val Arg Glu 
                165                 170                 175


Glu Ala Gln Lys Phe Leu Arg Gly Leu Gln Val Asn Gly Ser Arg Pro 
            180                 185                 190


Gly Thr Phe Val Gly Val His Val Arg Arg Gly Asp Tyr Val His Val 
        195                 200                 205


Met Pro Lys Val Trp Lys Gly Val Val Ala Asp Arg Arg Tyr Leu Gln 
    210                 215                 220


Gln Ala Leu Asp Trp Phe Arg Ala Arg Tyr Ser Ser Leu Ile Phe Val 
225                 230                 235                 240


Val Thr Ser Asn Gly Met Ala Trp Cys Arg Glu Asn Ile Asp Thr Ser 
                245                 250                 255


His Gly Asp Val Val Phe Ala Gly Asp Gly Ile Glu Gly Ser Pro Ala 
            260                 265                 270


Lys Asp Phe Ala Leu Leu Thr Gln Cys Asn His Thr Ile Met Thr Ile 
        275                 280                 285


Gly Thr Phe Gly Ile Trp Ala Ala Tyr Leu Thr Gly Gly Asp Thr Ile 
    290                 295                 300


Tyr Leu Ala Asn Tyr Thr Leu Pro Asp Ser Pro Phe Leu Lys Ile Phe 
305                 310                 315                 320


Lys Pro Glu Ala Ala Phe Leu Pro Glu Trp Thr Gly Ile Ala Ala Asp 
                325                 330                 335


Leu Ser Pro Leu Leu Lys His 
            340


<210>  9404
<211>  312
<212>  DNA
<213>  Homo sapiens

<400>  9404
aggtgcctgc ccaaccactc tgtcccggtt tccttcagca ggaccaggtc cttccttgtc     60

tccttcccct cagcagtttc tatgaaccac cctggcagta atggtgcaga tggctcgcgc    120

acagctggtg gtgacccgac tttcctgcct ccaccctggg gctcctcaga ggcttcatgg    180

aacccaaact gctggtctca cctccgagcc ctgccgtcgc ccagggaggg cggctccgtc    240

cctcctgcac tccctaatcc cgctctgaat caccgcttct gttctgggtc ggagaataaa    300

ggtggggttt cc                                                        312


<210>  9405
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  9405

Met Asn His Pro Gly Ser Asn Gly Ala Asp Gly Ser Arg Thr Ala Gly 
1               5                   10                  15


Gly Asp Pro Thr Phe Leu Pro Pro Pro Trp Gly Ser Ser Glu Ala Ser 
            20                  25                  30


Trp Asn Pro Asn Cys Trp Ser His Leu Arg Ala Leu Pro Ser Pro Arg 
        35                  40                  45


Glu Gly Gly Ser Val Pro Pro Ala Leu Pro Asn Pro Ala Leu Asn His 
    50                  55                  60


Arg Phe Cys Ser Gly Ser Glu Asn Lys Gly Gly Val 
65                  70                  75


<210>  9406
<211>  348
<212>  DNA
<213>  Homo sapiens

<400>  9406
ctcttggctg ctctaggtca agcccagcgc agcatctcac aggccacctc ttccacgtgc     60

cgcggatacc ccggggacgg ctccggctcc aactcccact ccggctcctg ctgcagctcc    120

agccctgacc ccttcctcag ggccgggctc agcggctctg actctggagg aggagctgca    180

ggaagcgatc cggagggcgc agacggagtc tcgcgctact ggcaggctgg agtgcagtgg    240

cacaatctcg gctcactgca acctccacct cccggattca agcagttctc ctgcctcagc    300

ctcccgagta gctgggacta caggtgagcc ctcaatgcca tcgccagc                 348


<210>  9407
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  9407

Leu Leu Ala Ala Leu Gly Gln Ala Gln Arg Ser Ile Ser Gln Ala Thr 
1               5                   10                  15


Ser Ser Thr Cys Arg Gly Tyr Pro Gly Asp Gly Ser Gly Ser Asn Ser 
            20                  25                  30


His Ser Gly Ser Cys Cys Ser Ser Ser Pro Asp Pro Phe Leu Arg Ala 
        35                  40                  45


Gly Leu Ser Gly Ser Asp Ser Gly Gly Gly Ala Ala Gly Ser Asp Pro 
    50                  55                  60


Glu Gly Ala Asp Gly Val Ser Arg Tyr Trp Gln Ala Gly Val Gln Trp 
65                  70                  75                  80


His Asn Leu Gly Ser Leu Gln Pro Pro Pro Pro Gly Phe Lys Gln Phe 
                85                  90                  95


Ser Cys Leu Ser Leu Pro Ser Ser Trp Asp Tyr Arg 
            100                 105


<210>  9408
<211>  1122
<212>  DNA
<213>  Homo sapiens

<400>  9408
gttgcgccct gtgggcatgg cttatgggcg ctcgccctct tggctgctct aggtcaagcc     60

cagcgcagca tctcacaggc cacctcttcc acgtgccgcg gataccccgg ggacggctcc    120

ggctccaact cccactccgg ctcctgctgc agctccagcc ctgacccctt cctcagggcc    180

gggctcagcg gctctgactc tggaggagga gctgcaggaa gcgatccgga gggcgcagtt    240

gcttcctaac cggggcatcg atgacatcct ggaggatcag gtggagcctg atgaccccct    300

gccccctatt cccctggact tccctggctc cttcgacgtg ctgtccccct ccccggactc    360

tgaaggcctc tcatctgttt tctcctcttc actcccgtct cccacgaact cctcctcccc    420

ttctcccagg gaccccacgg actccctgga ctggctggag gccctgagcg ggggtcctcc    480

tctgggttct ggtcccccac cccccagcat cttctccgct gacttatctg actccagcag    540

cagccggctg tgggacctgc tggaggatcc atggtgatgg attctaggat ttacagagac    600

agagaactga tgggggtgga gagaagctcc ttgtgggagg agagggaact accagcagag    660

cccctcctac cgcagacaca ggatcggaga caacctccaa ccccacctgc ctcctgaagt    720

gctgctgaca tgcaactgcc ttaactttgc ctacctggcc tccttatgat ccccctccgg    780

cgtggtatgg ttggggggct tcttttgctg ctggccacgg caaacaagct gcttgctgct    840

tccttcagag acctcatgga tgttcttaca tgcccccgac cccggtagat ggctccctgt    900

tgtttgggga gcctggaagg tggttatgcc ttttggatgc aggagaggag caagaaagag    960

tggagaggga gaatggggga gccggaccct gacctccctg ggttctggtt ggagatgaaa   1020

aaattagaag catcaggtct aagatcagct tctcttggaa gcagagcctg agacaagata   1080

taaatgccag tcatttatta aagaagtgtt ctggctgggt gc                      1122


<210>  9409
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  9409

Met Thr Ser Trp Arg Ile Arg Trp Ser Leu Met Thr Pro Cys Pro Leu 
1               5                   10                  15


Phe Pro Trp Thr Ser Leu Ala Pro Ser Thr Cys Cys Pro Pro Pro Arg 
            20                  25                  30


Thr Leu Lys Ala Ser His Leu Phe Ser Pro Leu His Ser Arg Leu Pro 
        35                  40                  45


Arg Thr Pro Pro Pro Leu Leu Pro Gly Thr Pro Arg Thr Pro Trp Thr 
    50                  55                  60


Gly Trp Arg Pro 
65


<210>  9410
<211>  2161
<212>  DNA
<213>  Homo sapiens

<400>  9410
gggcaggtgg agccgggggc agggctgcct ccagcctgca cgctggctgg ctcgtagccc     60

cagaatggcg ctggcccgcg gcgctgcgct ggcagggagc aggcgggagg cccgaggaag    120

ggagcctgct gcccgcccac ccgcctgcac aggctgtgta agggggctgg gcacgcatat    180

cccgccaaca actgcagctc ccaccagcct gccaggccag gctcctggac actcccttcc    240

cgccttcctc ctcccacctc cctcctccct ccacagtcct ccagcttcgg atccacagac    300

ggaatcagga gcagaatcca gttcaggcgc ccatctccca gcaatcaagt cttgctccct    360

ggcctgccct ccggcaccct ggagccccgc tttccacaca gccttgctcc tcccggcctg    420

gcttgctgcc tgcaggcctc tcagggtcct tcaccgtctc tccagtctcg gatccggacc    480

cgtggatctc agcctcagac cctcctctgg ccccggcctt gccctcgggc acggcccctt    540

tcctcttcag ccctggggtc ctgctccccg agccagaata ttgtcctcct tggaggtccc    600

caaagaagga gtctcccaag atctcccaac gttggaggga gtccaagccc agggggaact    660

tgacatacca ccagtacatg cccccagagc cgagacaggg atccagggcg gacccccaag    720

ccgaggggtc cgccctgggt cctcctgggc catctctgtg ggaagggaca gactcgcagc    780

agccacatcc taggatgaag ccctctcccc tcactccctg cccaccagga gtccctagcc    840

cctcgccccc cccacacaag ttggaacttc agacccttaa actggaggag ctgacggtct    900

cagagctccg gcagcagctg cgcctgcggg gcctcccagt gtcggggacc aagtctatgc    960

tcctggagcg catgcgcggc ggcgcgccgc cccgcgagcg gccgaagccg cggcgcgagg   1020

acagtcccgc gggtgctccc tggccgcgcc tcaagcccaa ggccctggca gccgcccggc   1080

gtcagggctc ggtcaagccc agcgcagcat ctcacaggcc acctcttcca cgtgccgcgg   1140

ataccccggg gacggctccg gctccaactc ccactccggc tcctgctgca gctccagccc   1200

tgaccccttc ctcagggccg ggctcagcgg ctctgactct ggaggaggag ctgcaggaag   1260

cgatccggag ggcgcagttg cttcctaacc ggggcatcga tgacatcctg gaggatcagg   1320

tggagcctga tgaccccctg ccccctattc ccctggactt ccctggctcc ttcgacgtgc   1380

tgtccccctc cccggactct gaaggcctct catctgtttt ctcctcttca ctcccgtctc   1440

ccacgaactc ctcctcccct tctcccaggg accccacgga ctccctggac tggctggagg   1500

ccctgagcgg gggtcctcct ctgggttctg gtcccccacc ccccagcatc ttctccgctg   1560

acttatctga ctccagcagc agccggctgt gggacctgct ggaggatcca tggtgatgga   1620

ttctaggatt tacagagaca gagaactgat gggggtggag agaagctcct tgtgggagga   1680

gagggaacta ccagcagagc ccctcctacc gcagacacag gatcggagac aacctccaac   1740

cccacctgcc tcctgaagtg ctgctgacat gcaactgcct taactttgcc tacctggcct   1800

ccttatgatc cccctccggc gtggtatggt tggggggctt cttttgctgc tggccacggc   1860

aaacaagctg cttgctgctt ccttcagaga cctcatggat gttcttacat gcccccgacc   1920

ccggtagatg gctccctgtt gtttggggag cctggaaggt ggttatgcct tttggatgca   1980

ggagaggagc aagaaagagt ggagagggag aatgggggag ccggaccctg acctccctgg   2040

gttctggttg gagatgaaaa aattagaagc atcaggtcta agatcagctt ctcttggaag   2100

cagagcctga gacaagatat aaatgccagt catttattaa agaagtgttc tggctgggtg   2160

c                                                                   2161


<210>  9411
<211>  312
<212>  PRT
<213>  Homo sapiens

<400>  9411

Met Pro Pro Glu Pro Arg Gln Gly Ser Arg Ala Asp Pro Gln Ala Glu 
1               5                   10                  15


Gly Ser Ala Leu Gly Pro Pro Gly Pro Ser Leu Trp Glu Gly Thr Asp 
            20                  25                  30


Ser Gln Gln Pro His Pro Arg Met Lys Pro Ser Pro Leu Thr Pro Cys 
        35                  40                  45


Pro Pro Gly Val Pro Ser Pro Ser Pro Pro Pro His Lys Leu Glu Leu 
    50                  55                  60


Gln Thr Leu Lys Leu Glu Glu Leu Thr Val Ser Glu Leu Arg Gln Gln 
65                  70                  75                  80


Leu Arg Leu Arg Gly Leu Pro Val Ser Gly Thr Lys Ser Met Leu Leu 
                85                  90                  95


Glu Arg Met Arg Gly Gly Ala Pro Pro Arg Glu Arg Pro Lys Pro Arg 
            100                 105                 110


Arg Glu Asp Ser Pro Ala Gly Ala Pro Trp Pro Arg Leu Lys Pro Lys 
        115                 120                 125


Ala Leu Ala Ala Ala Arg Arg Gln Gly Ser Val Lys Pro Ser Ala Ala 
    130                 135                 140


Ser His Arg Pro Pro Leu Pro Arg Ala Ala Asp Thr Pro Gly Thr Ala 
145                 150                 155                 160


Pro Ala Pro Thr Pro Thr Pro Ala Pro Ala Ala Ala Pro Ala Leu Thr 
                165                 170                 175


Pro Ser Ser Gly Pro Gly Ser Ala Ala Leu Thr Leu Glu Glu Glu Leu 
            180                 185                 190


Gln Glu Ala Ile Arg Arg Ala Gln Leu Leu Pro Asn Arg Gly Ile Asp 
        195                 200                 205


Asp Ile Leu Glu Asp Gln Val Glu Pro Asp Asp Pro Leu Pro Pro Ile 
    210                 215                 220


Pro Leu Asp Phe Pro Gly Ser Phe Asp Val Leu Ser Pro Ser Pro Asp 
225                 230                 235                 240


Ser Glu Gly Leu Ser Ser Val Phe Ser Ser Ser Leu Pro Ser Pro Thr 
                245                 250                 255


Asn Ser Ser Ser Pro Ser Pro Arg Asp Pro Thr Asp Ser Leu Asp Trp 
            260                 265                 270


Leu Glu Ala Leu Ser Gly Gly Pro Pro Leu Gly Ser Gly Pro Pro Pro 
        275                 280                 285


Pro Ser Ile Phe Ser Ala Asp Leu Ser Asp Ser Ser Ser Ser Arg Leu 
    290                 295                 300


Trp Asp Leu Leu Glu Asp Pro Trp 
305                 310


<210>  9412
<211>  1857
<212>  DNA
<213>  Homo sapiens

<400>  9412
agactcaacc cgccccagag cacagcttcg ccgagcccac ctggtcccca tcccggcctt     60

ggcaatgacc ctggcggctt cctcccagcg ttcccaaatc attcgctcca agttccgatc    120

tgtcctccag cttcggatcc acagacggaa tcaggagcag atctcggatc cggacccgtg    180

gatctcagcc tcagaccctc ctctggcccc ggccttgccc tcgggcacgg cccctttcct    240

cttcagccct ggggtcctgc tccccgagcc agaatattgt cctccttgga ggtccccaaa    300

gaaggagtct cccaagatct cccaacgttg gagggagtcc aagcccaggg ggaacttgac    360

ataccaccag tacatgcccc cagagccgag acagggatcc agggcggacc cccaagccga    420

ggggtccgcc ctgggtcctc ctgggccatc tctgtgggaa gggacagact cgcagcagcc    480

acatcctagg atgaagccct ctcccctcac tccctgccca ccaggagtcc ctagcccctc    540

gcccccccca cacaagttgg aacttcagac ccttaaactg gaggagctga cggtctcaga    600

gctccggcag cagctgcgcc tgcggggcct cccagtgtcg gggaccaagt ctatgctcct    660

ggagcgcatg cgcggcggcg cgccgccccg cgagcggccg aagccgcggc gcgaggacag    720

tcccgcgggt gctccctggc cgcgcctcaa gcccaaggcc ctggcagccg cccggcgtca    780

gggctcggtc aagcccagcg cagcatctca caggccacct cttccacgtg ccgcggatac    840

cccggggacg gctccggctc caactcccac tccggctcct gctgcagctc cagccctgac    900

cccttcctca gggccgggct cagcggctct gactctggag gaggagctgc aggaagcgat    960

ccggagggcg cagttgcttc ctaaccgggg catcgatgac atcctggagg atcaggtgga   1020

gcctgatgac cccctgcccc ctattcccct ggacttccct ggctccttcg acgtgctgtc   1080

cccctccccg gactctgaag gcctctcatc tgttttctcc tcttcactcc cgtctcccac   1140

gaactcctcc tccccttctc ccagggaccc cacggactcc ctggactggc tggaggccct   1200

gagcgggggt cctcctctgg gttctggtcc cccacccccc agcatcttct ccgctgactt   1260

atctgactcc agcagcagcc ggctgtggga cctgctggag gatccatggt gatggattct   1320

aggatttaca gagacagaga actgatgggg gtggagagaa gctccttgtg ggaggagagg   1380

gaactaccag cagagcccct cctaccgcag acacaggatc ggagacaacc tccaacccca   1440

cctgcctcct gaagtgctgc tgacatgcaa ctgccttaac tttgcctacc tggcctcctt   1500

atgatccccc tccggcgtgg tatggttggg gggcttcttt tgctgctggc cacggcaaac   1560

aagctgcttg ctgcttcctt cagagacctc atggatgttc ttacatgccc ccgaccccgg   1620

tagatggctc cctgttgttt ggggagcctg gaaggtggtt atgccttttg gatgcaggag   1680

aggagcaaga aagagtggag agggagaatg ggggagccgg accctgacct ccctgggttc   1740

tggttggaga tgaaaaaatt agaagcatca ggtctaagat cagcttctct tggaagcaga   1800

gcctgagaca agatataaat gccagtcatt tattaaagaa gtgttctggc tgggtgc      1857


<210>  9413
<211>  415
<212>  PRT
<213>  Homo sapiens

<400>  9413

Met Thr Leu Ala Ala Ser Ser Gln Arg Ser Gln Ile Ile Arg Ser Lys 
1               5                   10                  15


Phe Arg Ser Val Leu Gln Leu Arg Ile His Arg Arg Asn Gln Glu Gln 
            20                  25                  30


Ile Ser Asp Pro Asp Pro Trp Ile Ser Ala Ser Asp Pro Pro Leu Ala 
        35                  40                  45


Pro Ala Leu Pro Ser Gly Thr Ala Pro Phe Leu Phe Ser Pro Gly Val 
    50                  55                  60


Leu Leu Pro Glu Pro Glu Tyr Cys Pro Pro Trp Arg Ser Pro Lys Lys 
65                  70                  75                  80


Glu Ser Pro Lys Ile Ser Gln Arg Trp Arg Glu Ser Lys Pro Arg Gly 
                85                  90                  95


Asn Leu Thr Tyr His Gln Tyr Met Pro Pro Glu Pro Arg Gln Gly Ser 
            100                 105                 110


Arg Ala Asp Pro Gln Ala Glu Gly Ser Ala Leu Gly Pro Pro Gly Pro 
        115                 120                 125


Ser Leu Trp Glu Gly Thr Asp Ser Gln Gln Pro His Pro Arg Met Lys 
    130                 135                 140


Pro Ser Pro Leu Thr Pro Cys Pro Pro Gly Val Pro Ser Pro Ser Pro 
145                 150                 155                 160


Pro Pro His Lys Leu Glu Leu Gln Thr Leu Lys Leu Glu Glu Leu Thr 
                165                 170                 175


Val Ser Glu Leu Arg Gln Gln Leu Arg Leu Arg Gly Leu Pro Val Ser 
            180                 185                 190


Gly Thr Lys Ser Met Leu Leu Glu Arg Met Arg Gly Gly Ala Pro Pro 
        195                 200                 205


Arg Glu Arg Pro Lys Pro Arg Arg Glu Asp Ser Pro Ala Gly Ala Pro 
    210                 215                 220


Trp Pro Arg Leu Lys Pro Lys Ala Leu Ala Ala Ala Arg Arg Gln Gly 
225                 230                 235                 240


Ser Val Lys Pro Ser Ala Ala Ser His Arg Pro Pro Leu Pro Arg Ala 
                245                 250                 255


Ala Asp Thr Pro Gly Thr Ala Pro Ala Pro Thr Pro Thr Pro Ala Pro 
            260                 265                 270


Ala Ala Ala Pro Ala Leu Thr Pro Ser Ser Gly Pro Gly Ser Ala Ala 
        275                 280                 285


Leu Thr Leu Glu Glu Glu Leu Gln Glu Ala Ile Arg Arg Ala Gln Leu 
    290                 295                 300


Leu Pro Asn Arg Gly Ile Asp Asp Ile Leu Glu Asp Gln Val Glu Pro 
305                 310                 315                 320


Asp Asp Pro Leu Pro Pro Ile Pro Leu Asp Phe Pro Gly Ser Phe Asp 
                325                 330                 335


Val Leu Ser Pro Ser Pro Asp Ser Glu Gly Leu Ser Ser Val Phe Ser 
            340                 345                 350


Ser Ser Leu Pro Ser Pro Thr Asn Ser Ser Ser Pro Ser Pro Arg Asp 
        355                 360                 365


Pro Thr Asp Ser Leu Asp Trp Leu Glu Ala Leu Ser Gly Gly Pro Pro 
    370                 375                 380


Leu Gly Ser Gly Pro Pro Pro Pro Ser Ile Phe Ser Ala Asp Leu Ser 
385                 390                 395                 400


Asp Ser Ser Ser Ser Arg Leu Trp Asp Leu Leu Glu Asp Pro Trp 
                405                 410                 415


<210>  9414
<211>  1692
<212>  DNA
<213>  Homo sapiens

<400>  9414
gggggcaggt ggagccgggg gcagggctgc ctccagcctg cacgctggct ggctcgtagc     60

cccagaatgg cgctggcccg cggcgctgcg ctggcaggga gcaggcggga ggcccgagga    120

agggagcctg ctgcccgccc acccgcctgc acaggctgtg taagggggct gggcacgcat    180

atcccgccaa caactgcagc tcccaccagc ctgccaggcc aggctcctgg acactccctt    240

cccgccttcc tcctcccacc tccctcctcc ctccacagtc ctccagcttc ggatccacag    300

acggaatcag gagcagaatc cagttcaggc gcccatctcc cagcaatcaa gtcttgctcc    360

ctggcctgcc ctccggcacc ctggagcccc gctttccaca cagccttgct cctcccggcc    420

tggcttgctg cctgcaggcc tctcagggtc cttcaccgtc tctccagtct cggatccgga    480

cccgtggatc tcagcctcag accctcctct ggccccggcc ttgccctcgg gcacggcccc    540

tttcctcttc agccctgggg tcctgctccc cgagccagaa tattgtcctc cttggaggtc    600

cccaaagaag gagtctccca agatctccca acgttggagg gagtccaagc ccagggggaa    660

cttgacatac caccagtaca tgcccccaga gccgagacag ggatccaggg cggaccccca    720

agccgagggg tccgccctgg gtcctcctgg gccatctctg tgggaaggga cagactcgca    780

gcagccacat cctaggatga agccctctcc cctcactccc tgcccaccag gagtccctag    840

cccctcgccc cccccacaca agttggaact tcagaccctt aaactggagg agctgacggt    900

caagcccagc gcagcatctc acaggccacc tcttccacgt gccgcggata ccccggggac    960

ggctccggct ccaactccca ctccggctcc tgctgcagct ccagccctga ccccttcctc   1020

agggccgggc tcagcggctc tgactctgga ggaggagctg caggaagcga tccggagggc   1080

gcagttgctt cctaaccggg gcatcgatga catcctggag gatcaggtgg agcctgatga   1140

ccccctgccc cctattcccc tggacttccc tggctccttc gacgtgctgt ccccctcccc   1200

ggactctgaa ggcctctcat ctgttttctc ctcttcactc ccgtctccca cgaactcctc   1260

ctccccttct cccagggacc ccacggactc cctggactgg ctggaggccc tgagcggggg   1320

tcctcctctg ggttctggtc ccccaccccc cagcatcttc tccgctgact tatctgactc   1380

cagcagcagc cggctgtggg acctgctgga ggatccatgg tgatggattc taggatttac   1440

agagacagag aactgatggg ggtggagaga agctccttgt gggaggagag ggaactacca   1500

gcagagcccc tcctaccgca gacacaggat cggagacaac ctccaacccc acctgcctcc   1560

tgaagtgctg ctgacatgca actgccttaa ctttgcctac ctggcctcct tatgatcccc   1620

ctccggcgtg gtatggttgg ggggcttctt ttgctgctgg ccacggcaaa caagctgctt   1680

gctgcttcct tc                                                       1692


<210>  9415
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  9415

Met Pro Pro Glu Pro Arg Gln Gly Ser Arg Ala Asp Pro Gln Ala Glu 
1               5                   10                  15


Gly Ser Ala Leu Gly Pro Pro Gly Pro Ser Leu Trp Glu Gly Thr Asp 
            20                  25                  30


Ser Gln Gln Pro His Pro Arg Met Lys Pro Ser Pro Leu Thr Pro Cys 
        35                  40                  45


Pro Pro Gly Val Pro Ser Pro Ser Pro Pro Pro His Lys Leu Glu Leu 
    50                  55                  60


Gln Thr Leu Lys Leu Glu Glu Leu Thr Val Lys Pro Ser Ala Ala Ser 
65                  70                  75                  80


His Arg Pro Pro Leu Pro Arg Ala Ala Asp Thr Pro Gly Thr Ala Pro 
                85                  90                  95


Ala Pro Thr Pro Thr Pro Ala Pro Ala Ala Ala Pro Ala Leu Thr Pro 
            100                 105                 110


Ser Ser Gly Pro Gly Ser Ala Ala Leu Thr Leu Glu Glu Glu Leu Gln 
        115                 120                 125


Glu Ala Ile Arg Arg Ala Gln Leu Leu Pro Asn Arg Gly Ile Asp Asp 
    130                 135                 140


Ile Leu Glu Asp Gln Val Glu Pro Asp Asp Pro Leu Pro Pro Ile Pro 
145                 150                 155                 160


Leu Asp Phe Pro Gly Ser Phe Asp Val Leu Ser Pro Ser Pro Asp Ser 
                165                 170                 175


Glu Gly Leu Ser Ser Val Phe Ser Ser Ser Leu Pro Ser Pro Thr Asn 
            180                 185                 190


Ser Ser Ser Pro Ser Pro Arg Asp Pro Thr Asp Ser Leu Asp Trp Leu 
        195                 200                 205


Glu Ala Leu Ser Gly Gly Pro Pro Leu Gly Ser Gly Pro Pro Pro Pro 
    210                 215                 220


Ser Ile Phe Ser Ala Asp Leu Ser Asp Ser Ser Ser Ser Arg Leu Trp 
225                 230                 235                 240


Asp Leu Leu Glu Asp Pro Trp 
                245


<210>  9416
<211>  1581
<212>  DNA
<213>  Homo sapiens

<400>  9416
agactcaacc cgccccagag cacagcttcg ccgagcccac ctggtcccca tcccggcctt     60

ggcaatgacc ctggcggctt cctcccagcg ttcccaaatc attcgctcca agttccgatc    120

tgtcctccag cttcggatcc acagacggaa tcaggagcag atctcggatc cggacccgtg    180

gatctcagcc tcagaccctc ctctggcccc ggccttgccc tcgggcacgg cccctttcct    240

cttcagccct ggggtcctgc tccccgagcc agaatattgt cctccttgga ggtccccaaa    300

gaaggagtct cccaagatct cccaacgttg gagggagtcc aagcccaggg ggaacttgac    360

ataccaccag tacatgcccc cagagccgag acagggatcc agggcggacc cccaagccga    420

ggggtccgcc ctgggtcctc ctgggccatc tctgtgggaa gggacagact cgcagcagcc    480

acatcctagg atgaagccct ctcccctcac tccctgccca ccaggagtcc ctagcccctc    540

gcccccccca cacaagttgg aacttcagac ccttaaactg gaggagctga cggtctcaga    600

gctccggcag cagctgcgcc tgcggggcct cccagtgtcg gggaccaagt ctatgctcct    660

ggagcgcatg cgcggcggcg cgccgccccg cgagcggccg aagccgcggc gcgaggacag    720

tcccgcgggt gctccctggc cgcgcctcaa gcccaaggcc ctggcagccg cccggcgtca    780

gggctcggtc aagcccagcg cagcatctca caggccacct cttccacgtg ccgcggatac    840

cccggggacg gctccggctc caactcccac tccggctcct gctgcagctc cagccctgac    900

cccttcctca gggccgggct cagcggctct gactctggag gaggagctgc aggaagcgat    960

ccggagggcg cagttgcttc ctaaccgggg catcgatgac atcctggagg atcaggtgga   1020

gcctgatgac cccctgcccc ctattcccct ggacttccct ggctccttcg acgtgctgtc   1080

cccctccccg gactctgaag gcctctcatc tgttttctcc tcttcactcc cgtctcccac   1140

gaactcctcc tccccttctc ccagggaccc cacggactcc ctggactggc tggaggccct   1200

gagcgggggt cctcctctgg gttctggtcc cccacccccc agcatcttct ccgctgactt   1260

atctgactcc agcagcagcc ggctgtggga cctgctggag gatccatggt gatggattct   1320

aggatttaca gagacagaga actgatgggg gtggagagaa gctccttgtg ggaggagagg   1380

gaactaccag cagagcccct cctaccgcag acacaggatc ggagacaacc tccaacccca   1440

cctgcctcct gaagtgctgc tgacatgcaa ctgccttaac tttgcctacc tggcctcctt   1500

atgatccccc tccggcgtgg tatggttggg gggcttcttt tgctgctggc cacggcaaac   1560

aagctgcttg ctgcttcctt c                                             1581


<210>  9417
<211>  415
<212>  PRT
<213>  Homo sapiens

<400>  9417

Met Thr Leu Ala Ala Ser Ser Gln Arg Ser Gln Ile Ile Arg Ser Lys 
1               5                   10                  15


Phe Arg Ser Val Leu Gln Leu Arg Ile His Arg Arg Asn Gln Glu Gln 
            20                  25                  30


Ile Ser Asp Pro Asp Pro Trp Ile Ser Ala Ser Asp Pro Pro Leu Ala 
        35                  40                  45


Pro Ala Leu Pro Ser Gly Thr Ala Pro Phe Leu Phe Ser Pro Gly Val 
    50                  55                  60


Leu Leu Pro Glu Pro Glu Tyr Cys Pro Pro Trp Arg Ser Pro Lys Lys 
65                  70                  75                  80


Glu Ser Pro Lys Ile Ser Gln Arg Trp Arg Glu Ser Lys Pro Arg Gly 
                85                  90                  95


Asn Leu Thr Tyr His Gln Tyr Met Pro Pro Glu Pro Arg Gln Gly Ser 
            100                 105                 110


Arg Ala Asp Pro Gln Ala Glu Gly Ser Ala Leu Gly Pro Pro Gly Pro 
        115                 120                 125


Ser Leu Trp Glu Gly Thr Asp Ser Gln Gln Pro His Pro Arg Met Lys 
    130                 135                 140


Pro Ser Pro Leu Thr Pro Cys Pro Pro Gly Val Pro Ser Pro Ser Pro 
145                 150                 155                 160


Pro Pro His Lys Leu Glu Leu Gln Thr Leu Lys Leu Glu Glu Leu Thr 
                165                 170                 175


Val Ser Glu Leu Arg Gln Gln Leu Arg Leu Arg Gly Leu Pro Val Ser 
            180                 185                 190


Gly Thr Lys Ser Met Leu Leu Glu Arg Met Arg Gly Gly Ala Pro Pro 
        195                 200                 205


Arg Glu Arg Pro Lys Pro Arg Arg Glu Asp Ser Pro Ala Gly Ala Pro 
    210                 215                 220


Trp Pro Arg Leu Lys Pro Lys Ala Leu Ala Ala Ala Arg Arg Gln Gly 
225                 230                 235                 240


Ser Val Lys Pro Ser Ala Ala Ser His Arg Pro Pro Leu Pro Arg Ala 
                245                 250                 255


Ala Asp Thr Pro Gly Thr Ala Pro Ala Pro Thr Pro Thr Pro Ala Pro 
            260                 265                 270


Ala Ala Ala Pro Ala Leu Thr Pro Ser Ser Gly Pro Gly Ser Ala Ala 
        275                 280                 285


Leu Thr Leu Glu Glu Glu Leu Gln Glu Ala Ile Arg Arg Ala Gln Leu 
    290                 295                 300


Leu Pro Asn Arg Gly Ile Asp Asp Ile Leu Glu Asp Gln Val Glu Pro 
305                 310                 315                 320


Asp Asp Pro Leu Pro Pro Ile Pro Leu Asp Phe Pro Gly Ser Phe Asp 
                325                 330                 335


Val Leu Ser Pro Ser Pro Asp Ser Glu Gly Leu Ser Ser Val Phe Ser 
            340                 345                 350


Ser Ser Leu Pro Ser Pro Thr Asn Ser Ser Ser Pro Ser Pro Arg Asp 
        355                 360                 365


Pro Thr Asp Ser Leu Asp Trp Leu Glu Ala Leu Ser Gly Gly Pro Pro 
    370                 375                 380


Leu Gly Ser Gly Pro Pro Pro Pro Ser Ile Phe Ser Ala Asp Leu Ser 
385                 390                 395                 400


Asp Ser Ser Ser Ser Arg Leu Trp Asp Leu Leu Glu Asp Pro Trp 
                405                 410                 415


<210>  9418
<211>  1869
<212>  DNA
<213>  Homo sapiens

<400>  9418
cttctgaatc tcccactttc taagtctact cttcagtcac tgttaagttt catatataat     60

agatagataa atgattgata gatagctaga gatcaaatag tgccaggaac tgtgatttaa    120

actgaagatc ctctttcatc aggccccact tccttcgctt gctgacctca cttcctacag    180

ctctgaattc acttcccttt cagaacgaca gatctttttc tctgagtgcc cttcctggaa    240

gggcctgctt tctgccccag tttccccccc attacccttg accttaacac cacttcttgg    300

cattctcagg gtttctggct tatggtgggc ttgatgccct atgtgcaaga atgagagagg    360

atcttttggg acagctaact atcagtctct aagttcctct agcagcctgg attgtgaagc    420

cctttcctcc ttcacttcct gtacattcct gccaagtgtg cgtttatttc ttctgtttct    480

gacctcattt cctgtccttg gcctgatctc attttccact ggcaaactgc catcccactc    540

ccacttcctg actctccatt ctttttcttt cctttgggaa ttcaggatga ataattcttt    600

gactgaaagg gaactctttg tccagtatcc tttgtcctcc ttgagctgtc tctgctgaga    660

actacaagtc ccacaatgca caagaggtga tcttaaaata ctcgagaaac ttgtataccc    720

ttctatcaag tagggatttg ctcacggaga ccctttgggt gttgactgta gaatggacta    780

caactcccag aagactttgg tggagctccc cactatcttc atgctctatt accctgaagc    840

ttcctgggag ttgtagtcca atcacttgtt tccacttctc tattttctca gactctctat    900

tcaacgctgc ctgctctcct ggatagtaac cctttcacag ctggtgcaga gctgccgggg    960

cctggcgcgg agctgggggc catgcctcca ggattgagac ctaccctggg cgtgttccag   1020

gcagccttgg agctgaccag ccagtgcgag ctgcaccctg acctcgtgtc tcagactttt   1080

ggctacttgt tcttcttctc caacgcatcc cttctcaact cgctgatgga acgaggtcaa   1140

ggccggcctt tctatcaatg gtcccgagct gttcaaatcc gaaccaacct ggacctcgtc   1200

ttggactggc tacagggagc tgggctgggc gacattgcca ctgagttctt ccggaaactc   1260

tccatggctg tgaacctgct ctgtgtgccc cgcacttccc tgctcaaggc ttcatggagc   1320

agcctaagaa ccgaccaccc caccttgacc cccgcccagc tgcaccatct gctcagccac   1380

tatcagctgg gccctggccg cgggccgcca gccgcgtggg accctccccc tgcagagcgg   1440

gaggctgtgg acacagggga catcttcgaa agcttctcct cgcacccgcc cctcatcctc   1500

cccctgggga gctcgcgcct gcgcctcact ggtccagtga cggacgatgc cttgcaccgt   1560

gaactccgta ggctccgccg cctcctctgg gatcttgagc agcaggagct gccagccaat   1620

tatcgccatg ggcctcccgt ggccacgtct ccttgagaac caataccaaa cgagcgcgcg   1680

aaccttgaaa tgtcacgggc ttctacggac aggagcccgc ctgagcgcaa agctttctgg   1740

gagttgtagt tcttatcccg cgtggaatgt tgggagattg agttttcggg aagtagcgga   1800

tgggacggtg ggagcatggg cttaggatgt gaatgccagg gagcaataaa ggtatccgtg   1860

gtatcggca                                                           1869


<210>  9419
<211>  224
<212>  PRT
<213>  Homo sapiens

<400>  9419

Met Pro Pro Gly Leu Arg Pro Thr Leu Gly Val Phe Gln Ala Ala Leu 
1               5                   10                  15


Glu Leu Thr Ser Gln Cys Glu Leu His Pro Asp Leu Val Ser Gln Thr 
            20                  25                  30


Phe Gly Tyr Leu Phe Phe Phe Ser Asn Ala Ser Leu Leu Asn Ser Leu 
        35                  40                  45


Met Glu Arg Gly Gln Gly Arg Pro Phe Tyr Gln Trp Ser Arg Ala Val 
    50                  55                  60


Gln Ile Arg Thr Asn Leu Asp Leu Val Leu Asp Trp Leu Gln Gly Ala 
65                  70                  75                  80


Gly Leu Gly Asp Ile Ala Thr Glu Phe Phe Arg Lys Leu Ser Met Ala 
                85                  90                  95


Val Asn Leu Leu Cys Val Pro Arg Thr Ser Leu Leu Lys Ala Ser Trp 
            100                 105                 110


Ser Ser Leu Arg Thr Asp His Pro Thr Leu Thr Pro Ala Gln Leu His 
        115                 120                 125


His Leu Leu Ser His Tyr Gln Leu Gly Pro Gly Arg Gly Pro Pro Ala 
    130                 135                 140


Ala Trp Asp Pro Pro Pro Ala Glu Arg Glu Ala Val Asp Thr Gly Asp 
145                 150                 155                 160


Ile Phe Glu Ser Phe Ser Ser His Pro Pro Leu Ile Leu Pro Leu Gly 
                165                 170                 175


Ser Ser Arg Leu Arg Leu Thr Gly Pro Val Thr Asp Asp Ala Leu His 
            180                 185                 190


Arg Glu Leu Arg Arg Leu Arg Arg Leu Leu Trp Asp Leu Glu Gln Gln 
        195                 200                 205


Glu Leu Pro Ala Asn Tyr Arg His Gly Pro Pro Val Ala Thr Ser Pro 
    210                 215                 220


<210>  9420
<211>  3310
<212>  DNA
<213>  Homo sapiens

<400>  9420
ggcagggcca accctaccca gatctcctcc cccaggcctg gtctcctcac aggacgcccc     60

ctccccgctc ttcctgccgg gtttcctctt gccttttcct gtcccccacc cagtgctggg    120

agccgtggca gaggcaagag cagtggaact gacccaggcc agtggagcca gggcctccgg    180

gtgtgccgga cccgaagcag gggccatgct gtctggtgaa cggaaggagg gcggaagccc    240

ccgcttcggg aagcttcatc tccccgtggg cctgtggatc aattccccca ggaagcagct    300

ggcgaagctg gggcggcgct ggcccagcgc agcctctgtc aagtcttctt cgtcggacac    360

ggggagccgc agcagcgagc cgctacctcc gcccccgccg cacgtggagc tgcggcgagt    420

gggcgctgtc aaggcggccg ggggagcctc cggtagccgc gccaagcgca tctcccagct    480

cttccggggc tcggggaccg ggaccacggg gtccagcggc gcaggaggcc ctgggacccc    540

ggggggcgcg cagcgctggg ccagcgagaa gaagctgccg gagctggcgg cgggcgtggc    600

ccccgagccc ccgctggcta cccgcgccac ggcgcctccg ggggtcctca agatcttcgg    660

cgccggactg gcatcgggcg ccaactacaa gagcgtgctg gccacggcgc gctccacggc    720

gcgcgagctc gtggccgagg cgctagagcg ctacggccta gcaggcagcc ccggcggtgg    780

ccccggcgag agcagctgcg tggacgcctt cgctttgtgc gacgctctgg gccggcccgc    840

ggcggcgggc gtgggaagcg gcgagtggcg ggcggagcac ctgcgcgtgc tgggcgactc    900

cgagcgcccg ctgctggtgc aggagctgtg gcgggcgcgg cccggctggg cgcggcgctt    960

cgagttgcgc ggccgcgagg aggcgcggcg cctggagcag gaggccttcg gggccgcgga   1020

cagcgaaggc accggcgccc cttcgtggcg gccacagaag aaccgctccc gggcggcgtc   1080

gggtggggca gcgctggcca gtcctggccc ggggaccgga tcaggggccc cagctgggtc   1140

tggaggcaag gagcgctcag aaaacttgtc tttgcggcgc agcgtgtcgg agcttagcct   1200

tcaggggcgg cggcggcggc agcaggagcg gagacagcag gcacttagca tggccccagg   1260

ggcagccgac gcccaaatcg gaactgcaga ccccggggac ttcgatcagt tgactcagtg   1320

cctcatccag gcccccagca accgccccta cttcctgctg ctccagggct accaggacgc   1380

ccaggacttt gtggtgtatg tgatgacgcg agagcagcac gtgtttgggc gaggtgggaa   1440

ctcgtctggc cgcggggggt ccccggctcc ctatgtggac accttcctca acgccccgga   1500

catcctgccg cgtcactgca cagtgcgcgc gggccctgag cacccggcca tggtgcgccc   1560

gtcccggggc gccccagtca cgcacaacgg gtgcctcctg ctgcgggagg ctgagctgca   1620

cccgggcgac ctcctggggc tgggcgagca cttcctgttc atgtacaagg acccccgcac   1680

tgggggctcg gggcctgcga ggccgccgtg gctgcccgcg cgccccgggg ccacgccgcc   1740

aggccctggc tgggccttct cctgtcgcct gtgcggccgc ggcctgcagg agcgcggcga   1800

ggcactggcc gcctacctgg acggccgtga gccagtcctg cgcttccggc cgcgcgagga   1860

ggaggcgctg ctgggcgaga tcgtgcgcgc cgcagccgcc ggctcgggag acctgccgcc   1920

cctcgggccc gccacgctgc tggcgctgtg cgtgcagcat tccgcccgtg agctggagct   1980

gggccacctg ccacgactgc tgggccgcct ggcccggctc atcaaggagg ccgtctggga   2040

aaagattaag gaaattggag accgtcagcc agaaaaccac cctgaggggg tccccgaggt   2100

gcccctgact cctgaagctg tgtctgtgga gctgcggcca ctcatgctgt ggatggccaa   2160

caccacggag ctgcttagct ttgtgcagga gaaggtgctg gaaatggaga aggaggctga   2220

ccaagaggac ccacagctct gcaatgactt ggaattatgt gatgaggcca tggccctcct   2280

ggatgaggtc atcatgtgta ccttccagca gtctgtctac tacctcacca agactctcta   2340

ttcaacgctg cctgctctcc tggatagtaa ccctttcaca gctggtgcag agctgccggg   2400

gcctggcgcg gagctggggg ccatgcctcc aggattgaga cctaccctgg gcgtgttcca   2460

ggcagccttg gagctgacca gccagtgcga gctgcaccct gacctcgtgt ctcagacttt   2520

tggctacttg ttcttcttct ccaacgcatc ccttctcaac tcgctgatgg aacgaggtca   2580

aggccggcct ttctatcaat ggtcccgagc tgttcaaatc cgaaccaacc tggacctcgt   2640

cttggactgg ctacagggag ctgggctggg cgacattgcc actgagttct tccggaaact   2700

ctccatggct gtgaacctgc tctgtgtgcc ccgcacttcc ctgctcaagg cttcatggag   2760

cagcctaaga accgaccacc ccaccttgac ccccgcccag ctgcaccatc tgctcagcca   2820

ctatcagctg ggccctggcc gcgggccgcc agccgcgtgg gaccctcccc ctgcagagcg   2880

ggaggctgtg gacacagggg acatcttcga aagcttctcc tcgcacccgc ccctcatcct   2940

ccccctgggg agctcgcgcc tgcgcctcac tggtccagtg acggacgatg ccttgcaccg   3000

tgaactccgt aggctccgcc gcctcctctg ggatcttgag cagcaggagc tgccagccaa   3060

ttatcgccat gggcctcccg tggccacgtc tccttgagaa ccaataccaa acgagcgcgc   3120

gaaccttgaa atgtcacggg cttctacgga caggagcccg cctgagcgca aagctttctg   3180

ggagttgtag ttcttatccc gcgtggaatg ttgggagatt gagttttcgg gaagtagcgg   3240

atgggacggt gggagcatgg gcttaggatg tgaatgccag ggagcaataa aggtatccgt   3300

ggtatcggca                                                          3310


<210>  9421
<211>  963
<212>  PRT
<213>  Homo sapiens

<400>  9421

Met Leu Ser Gly Glu Arg Lys Glu Gly Gly Ser Pro Arg Phe Gly Lys 
1               5                   10                  15


Leu His Leu Pro Val Gly Leu Trp Ile Asn Ser Pro Arg Lys Gln Leu 
            20                  25                  30


Ala Lys Leu Gly Arg Arg Trp Pro Ser Ala Ala Ser Val Lys Ser Ser 
        35                  40                  45


Ser Ser Asp Thr Gly Ser Arg Ser Ser Glu Pro Leu Pro Pro Pro Pro 
    50                  55                  60


Pro His Val Glu Leu Arg Arg Val Gly Ala Val Lys Ala Ala Gly Gly 
65                  70                  75                  80


Ala Ser Gly Ser Arg Ala Lys Arg Ile Ser Gln Leu Phe Arg Gly Ser 
                85                  90                  95


Gly Thr Gly Thr Thr Gly Ser Ser Gly Ala Gly Gly Pro Gly Thr Pro 
            100                 105                 110


Gly Gly Ala Gln Arg Trp Ala Ser Glu Lys Lys Leu Pro Glu Leu Ala 
        115                 120                 125


Ala Gly Val Ala Pro Glu Pro Pro Leu Ala Thr Arg Ala Thr Ala Pro 
    130                 135                 140


Pro Gly Val Leu Lys Ile Phe Gly Ala Gly Leu Ala Ser Gly Ala Asn 
145                 150                 155                 160


Tyr Lys Ser Val Leu Ala Thr Ala Arg Ser Thr Ala Arg Glu Leu Val 
                165                 170                 175


Ala Glu Ala Leu Glu Arg Tyr Gly Leu Ala Gly Ser Pro Gly Gly Gly 
            180                 185                 190


Pro Gly Glu Ser Ser Cys Val Asp Ala Phe Ala Leu Cys Asp Ala Leu 
        195                 200                 205


Gly Arg Pro Ala Ala Ala Gly Val Gly Ser Gly Glu Trp Arg Ala Glu 
    210                 215                 220


His Leu Arg Val Leu Gly Asp Ser Glu Arg Pro Leu Leu Val Gln Glu 
225                 230                 235                 240


Leu Trp Arg Ala Arg Pro Gly Trp Ala Arg Arg Phe Glu Leu Arg Gly 
                245                 250                 255


Arg Glu Glu Ala Arg Arg Leu Glu Gln Glu Ala Phe Gly Ala Ala Asp 
            260                 265                 270


Ser Glu Gly Thr Gly Ala Pro Ser Trp Arg Pro Gln Lys Asn Arg Ser 
        275                 280                 285


Arg Ala Ala Ser Gly Gly Ala Ala Leu Ala Ser Pro Gly Pro Gly Thr 
    290                 295                 300


Gly Ser Gly Ala Pro Ala Gly Ser Gly Gly Lys Glu Arg Ser Glu Asn 
305                 310                 315                 320


Leu Ser Leu Arg Arg Ser Val Ser Glu Leu Ser Leu Gln Gly Arg Arg 
                325                 330                 335


Arg Arg Gln Gln Glu Arg Arg Gln Gln Ala Leu Ser Met Ala Pro Gly 
            340                 345                 350


Ala Ala Asp Ala Gln Ile Gly Thr Ala Asp Pro Gly Asp Phe Asp Gln 
        355                 360                 365


Leu Thr Gln Cys Leu Ile Gln Ala Pro Ser Asn Arg Pro Tyr Phe Leu 
    370                 375                 380


Leu Leu Gln Gly Tyr Gln Asp Ala Gln Asp Phe Val Val Tyr Val Met 
385                 390                 395                 400


Thr Arg Glu Gln His Val Phe Gly Arg Gly Gly Asn Ser Ser Gly Arg 
                405                 410                 415


Gly Gly Ser Pro Ala Pro Tyr Val Asp Thr Phe Leu Asn Ala Pro Asp 
            420                 425                 430


Ile Leu Pro Arg His Cys Thr Val Arg Ala Gly Pro Glu His Pro Ala 
        435                 440                 445


Met Val Arg Pro Ser Arg Gly Ala Pro Val Thr His Asn Gly Cys Leu 
    450                 455                 460


Leu Leu Arg Glu Ala Glu Leu His Pro Gly Asp Leu Leu Gly Leu Gly 
465                 470                 475                 480


Glu His Phe Leu Phe Met Tyr Lys Asp Pro Arg Thr Gly Gly Ser Gly 
                485                 490                 495


Pro Ala Arg Pro Pro Trp Leu Pro Ala Arg Pro Gly Ala Thr Pro Pro 
            500                 505                 510


Gly Pro Gly Trp Ala Phe Ser Cys Arg Leu Cys Gly Arg Gly Leu Gln 
        515                 520                 525


Glu Arg Gly Glu Ala Leu Ala Ala Tyr Leu Asp Gly Arg Glu Pro Val 
    530                 535                 540


Leu Arg Phe Arg Pro Arg Glu Glu Glu Ala Leu Leu Gly Glu Ile Val 
545                 550                 555                 560


Arg Ala Ala Ala Ala Gly Ser Gly Asp Leu Pro Pro Leu Gly Pro Ala 
                565                 570                 575


Thr Leu Leu Ala Leu Cys Val Gln His Ser Ala Arg Glu Leu Glu Leu 
            580                 585                 590


Gly His Leu Pro Arg Leu Leu Gly Arg Leu Ala Arg Leu Ile Lys Glu 
        595                 600                 605


Ala Val Trp Glu Lys Ile Lys Glu Ile Gly Asp Arg Gln Pro Glu Asn 
    610                 615                 620


His Pro Glu Gly Val Pro Glu Val Pro Leu Thr Pro Glu Ala Val Ser 
625                 630                 635                 640


Val Glu Leu Arg Pro Leu Met Leu Trp Met Ala Asn Thr Thr Glu Leu 
                645                 650                 655


Leu Ser Phe Val Gln Glu Lys Val Leu Glu Met Glu Lys Glu Ala Asp 
            660                 665                 670


Gln Glu Asp Pro Gln Leu Cys Asn Asp Leu Glu Leu Cys Asp Glu Ala 
        675                 680                 685


Met Ala Leu Leu Asp Glu Val Ile Met Cys Thr Phe Gln Gln Ser Val 
    690                 695                 700


Tyr Tyr Leu Thr Lys Thr Leu Tyr Ser Thr Leu Pro Ala Leu Leu Asp 
705                 710                 715                 720


Ser Asn Pro Phe Thr Ala Gly Ala Glu Leu Pro Gly Pro Gly Ala Glu 
                725                 730                 735


Leu Gly Ala Met Pro Pro Gly Leu Arg Pro Thr Leu Gly Val Phe Gln 
            740                 745                 750


Ala Ala Leu Glu Leu Thr Ser Gln Cys Glu Leu His Pro Asp Leu Val 
        755                 760                 765


Ser Gln Thr Phe Gly Tyr Leu Phe Phe Phe Ser Asn Ala Ser Leu Leu 
    770                 775                 780


Asn Ser Leu Met Glu Arg Gly Gln Gly Arg Pro Phe Tyr Gln Trp Ser 
785                 790                 795                 800


Arg Ala Val Gln Ile Arg Thr Asn Leu Asp Leu Val Leu Asp Trp Leu 
                805                 810                 815


Gln Gly Ala Gly Leu Gly Asp Ile Ala Thr Glu Phe Phe Arg Lys Leu 
            820                 825                 830


Ser Met Ala Val Asn Leu Leu Cys Val Pro Arg Thr Ser Leu Leu Lys 
        835                 840                 845


Ala Ser Trp Ser Ser Leu Arg Thr Asp His Pro Thr Leu Thr Pro Ala 
    850                 855                 860


Gln Leu His His Leu Leu Ser His Tyr Gln Leu Gly Pro Gly Arg Gly 
865                 870                 875                 880


Pro Pro Ala Ala Trp Asp Pro Pro Pro Ala Glu Arg Glu Ala Val Asp 
                885                 890                 895


Thr Gly Asp Ile Phe Glu Ser Phe Ser Ser His Pro Pro Leu Ile Leu 
            900                 905                 910


Pro Leu Gly Ser Ser Arg Leu Arg Leu Thr Gly Pro Val Thr Asp Asp 
        915                 920                 925


Ala Leu His Arg Glu Leu Arg Arg Leu Arg Arg Leu Leu Trp Asp Leu 
    930                 935                 940


Glu Gln Gln Glu Leu Pro Ala Asn Tyr Arg His Gly Pro Pro Val Ala 
945                 950                 955                 960


Thr Ser Pro 



<210>  9422
<211>  297
<212>  DNA
<213>  Homo sapiens

<400>  9422
ctgacctcgt gtctcagact tttggctact tgttcttctt ctccaacgca tcccttctca     60

actcgctgat ggaacgaggt caaggccggc ctttctatca atggtcccga gctgttcaaa    120

tccgaaccaa cctggacctc gtcttggact ggctacaggg agctgggctg ggcgacattg    180

ccactgagtt cttccggaaa ctctccatgg ctgtgaacct gctctgtgtg ccccgcactt    240

ccctgctcaa ggtgactcct ggtcagctat acctgacccc tgacctctga ctcctca       297


<210>  9423
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  9423

Met Glu Arg Gly Gln Gly Arg Pro Phe Tyr Gln Trp Ser Arg Ala Val 
1               5                   10                  15


Gln Ile Arg Thr Asn Leu Asp Leu Val Leu Asp Trp Leu Gln Gly Ala 
            20                  25                  30


Gly Leu Gly Asp Ile Ala Thr Glu Phe Phe Arg Lys Leu Ser Met Ala 
        35                  40                  45


Val Asn Leu Leu Cys Val Pro Arg Thr Ser Leu Leu Lys Val Thr Pro 
    50                  55                  60


Gly Gln Leu Tyr Leu Thr Pro Asp Leu 
65                  70


<210>  9424
<211>  150
<212>  DNA
<213>  Homo sapiens

<400>  9424
ctgacagctc ccagccaacc ttcacctcgt tccatcagcg agttgagaag ggatgcgttg     60

gagaagaaga acaagtagcc aaaactctgt caacttctca tccagtggga tctctccccc    120

accatctccc ataatggttt cttcctaagg                                     150


<210>  9425
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9425

Met Arg Trp Arg Arg Arg Thr Ser Ser Gln Asn Ser Val Asn Phe Ser 
1               5                   10                  15


Ser Ser Gly Ile Ser Pro Pro Pro Ser Pro Ile Met Val Ser Ser 
            20                  25                  30


<210>  9426
<211>  828
<212>  DNA
<213>  Homo sapiens

<400>  9426
ggttcaaatg attcttctgc ctcagcctcc cgagtagtgg gattacaggt gtgagccacc     60

acacccggtg ttttggggtt attaagcaag gggccccccc atagaatgct gggagatgta    120

gatccactgc acttagaggg aagcccaaac tcaccttagg agagctcacc taagcacgaa    180

ctcaccttag gaagaaacca ttatgggaga tggtggggga gagatcccac tggatgagaa    240

gttgacagag atcagtgtga gaattcaccg cagcccattg ggcttggagc ttggatagca    300

gtgagcgagt tcattcttgg aggcgaggaa gcacaaatcc actggaccta cagatggaag    360

ttccagaaag aaaccattca gagtggggga aacgttccat cctattgagc tagggcctaa    420

ccagagaggt ttaaggagtt tcttgggggt aaaaattgga gaagaggacc tgaaggagct    480

agatcactca taatcatagg gtgtgtatgt tttaaaaagt aaggagagac cattctaaag    540

cttgtgggat tagaatttgt ctcaagagcc aggcgtggtg gctcatgcct gtaatcccgg    600

cactttggga ggccgaggcg ggcagatcac ctgaagtcgg gagatcgaga ccatcctggc    660

taacatggtg aaaccccgtc tctactaaaa atgcaaaaaa ttagccgggc atggtagcac    720

atgcctgtaa tcccagctac ttgggaggct gaggcaggag aatcacttga acctgggagg    780

cagaggttgc agtgagccaa aattgagcca ttgcacccca gcctgggc                 828


<210>  9427
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9427

Met Gly Asp Gly Gly Gly Glu Ile Pro Leu Asp Glu Lys Leu Thr Glu 
1               5                   10                  15


Ile Ser Val Arg Ile His Arg Ser Pro Leu Gly Leu Glu Leu Gly 
            20                  25                  30


<210>  9428
<211>  922
<212>  DNA
<213>  Homo sapiens

<400>  9428
ttggggctta ggcgggacgg gggctggttg ctggtggtgg cttggagtgg cctgaagtgg     60

ctccgaattg gggttagggc cttctgcagg catttcagac tgccttggag gaggtggggt    120

gtgtagcggg gtctgcggag tagtagatcc tgaggagcgt ttgtggagtc cagtggaatg    180

ggcaggagtc cgcaggggcc taagggattc gccctgtgtg gcaccggcgc cccttcgtgg    240

cggccacaga agaaccgctc ccgggcggcg tcgggtgggg cagcgctggc cagtcctggc    300

ccggggaccg gatcaggggc cccagctggg tctggaggca aggagcgctc agaaaacttg    360

tctttgcggc gcagcgtgtc ggagcttagc cttcaggggc ggcggcggcg gcagcaggag    420

cggagacagc aggcacttag catggcccca ggggcagccg acgcccaaat cggaactgca    480

gaccccgggg acttcgatca gttgactcag tgcctcatcc aggcccccag caaccgcccc    540

tacttcctgc tgctccaggg ctaccaggac gcccaggact ttgtggtgta tgtgatgacg    600

cgagagcagc acgtgtttgg gcgaggtggg aactcgtctg gccgcggggg gtccccggct    660

ccctatgtgg acaccttcct caacgccccg gacatcctgc cgcgtcactg cacagtgcgc    720

gcgggccctg agcacccggc catggtgcgc ccgtcccggg gcgccccagt cacgcacaac    780

gggtgcctcc tgctgcggga ggctgagctg cacccgggcg acctcctggg gctgggcgag    840

cacttcctgt tcatgtacaa ggacccccgc actgggggct cggggcctgc gaggccgccg    900

tggctgcccg cgcgccccgg gg                                             922


<210>  9429
<211>  247
<212>  PRT
<213>  Homo sapiens

<400>  9429

Met Gly Arg Ser Pro Gln Gly Pro Lys Gly Phe Ala Leu Cys Gly Thr 
1               5                   10                  15


Gly Ala Pro Ser Trp Arg Pro Gln Lys Asn Arg Ser Arg Ala Ala Ser 
            20                  25                  30


Gly Gly Ala Ala Leu Ala Ser Pro Gly Pro Gly Thr Gly Ser Gly Ala 
        35                  40                  45


Pro Ala Gly Ser Gly Gly Lys Glu Arg Ser Glu Asn Leu Ser Leu Arg 
    50                  55                  60


Arg Ser Val Ser Glu Leu Ser Leu Gln Gly Arg Arg Arg Arg Gln Gln 
65                  70                  75                  80


Glu Arg Arg Gln Gln Ala Leu Ser Met Ala Pro Gly Ala Ala Asp Ala 
                85                  90                  95


Gln Ile Gly Thr Ala Asp Pro Gly Asp Phe Asp Gln Leu Thr Gln Cys 
            100                 105                 110


Leu Ile Gln Ala Pro Ser Asn Arg Pro Tyr Phe Leu Leu Leu Gln Gly 
        115                 120                 125


Tyr Gln Asp Ala Gln Asp Phe Val Val Tyr Val Met Thr Arg Glu Gln 
    130                 135                 140


His Val Phe Gly Arg Gly Gly Asn Ser Ser Gly Arg Gly Gly Ser Pro 
145                 150                 155                 160


Ala Pro Tyr Val Asp Thr Phe Leu Asn Ala Pro Asp Ile Leu Pro Arg 
                165                 170                 175


His Cys Thr Val Arg Ala Gly Pro Glu His Pro Ala Met Val Arg Pro 
            180                 185                 190


Ser Arg Gly Ala Pro Val Thr His Asn Gly Cys Leu Leu Leu Arg Glu 
        195                 200                 205


Ala Glu Leu His Pro Gly Asp Leu Leu Gly Leu Gly Glu His Phe Leu 
    210                 215                 220


Phe Met Tyr Lys Asp Pro Arg Thr Gly Gly Ser Gly Pro Ala Arg Pro 
225                 230                 235                 240


Pro Trp Leu Pro Ala Arg Pro 
                245


<210>  9430
<211>  491
<212>  DNA
<213>  Homo sapiens

<400>  9430
tgattatctc tgggatggcc ggctactggg acgggcttgt ctttgccagg gcaggaactc     60

cacgccctgc caggactgct ctttacgctt tctctaacag tgttgcccaa aatgatcaag    120

gaggaaaaac cttctccaaa tatcgtaacc ccgggggagg cgaccacgga gtcgtccata    180

agcctccagc ctctgcagcc cgagaaaatg ctggcaagcc gccttctggg gctgctgatc    240

tgcggctccc tagcactgat aaccggcctt acctttgcgt aagcaaccca ttgaagaaga    300

caggcttggc ttggagatat ttcgtcgaag gaaggtgatc gatttcatca aatcctcact    360

gtttggcctt ggcagtggag cggccgagca aacccaggtc ccaaaagaaa aggccacaga    420

ttcgaggcaa caataaagat ttatcttgtt gtctaagcat ctgactcact ccccgggacg    480

ggactgattc t                                                         491


<210>  9431
<211>  107
<212>  PRT
<213>  Homo sapiens

<400>  9431

Met Ala Gly Tyr Trp Asp Gly Leu Val Phe Ala Arg Ala Gly Thr Pro 
1               5                   10                  15


Arg Pro Ala Arg Thr Ala Leu Tyr Ala Phe Ser Asn Ser Val Ala Gln 
            20                  25                  30


Asn Asp Gln Gly Gly Lys Thr Phe Ser Lys Tyr Arg Asn Pro Gly Gly 
        35                  40                  45


Gly Asp His Gly Val Val His Lys Pro Pro Ala Ser Ala Ala Arg Glu 
    50                  55                  60


Asn Ala Gly Lys Pro Pro Ser Gly Ala Ala Asp Leu Arg Leu Pro Ser 
65                  70                  75                  80


Thr Asp Asn Arg Pro Tyr Leu Cys Val Ser Asn Pro Leu Lys Lys Thr 
                85                  90                  95


Gly Leu Ala Trp Arg Tyr Phe Val Glu Gly Arg 
            100                 105


<210>  9432
<211>  1006
<212>  DNA
<213>  Homo sapiens

<400>  9432
atggggccgc attttaccct cctgtgtgcg gcgctggccg gttgcttgct tcctgccgag     60

gggtgtgtta tatgtgaccc gtctgtcgtg ctggcgctaa agtccctgga gaaagattac    120

ctgcctggcc acctggatgc gaagcatcac aaagccatga tggaaaggat gaggccacac    180

tgcaaaaggg gtcctggagt ttgctgaagg atctgaaacg catcacagac agtgatgtaa    240

aaggcgatct cttcgtgaag gagctatttt ggatgttgca cttgcaaaag gaaacctttg    300

ccacctatgt tgctcgattc caaaaagagg cttattgtcc caacaaatgt ggtgtgatgt    360

tgcaaactct gatctggtgc aagaactgca aaaaggaggt tcacgcttgt cgaaagtcct    420

acgattgcgg ggagcggaat gtggaagttc ctcaaatgga agacatgatc ctggactgtg    480

agttaaactg gcatcaggct tcggaaggcc tcactgatta cagcttttac agggtttggg    540

ggaacaatac ggagaccttg gtgtccaagg ggaaagaggc caccctgacc aagcccatgg    600

tgggtccaga ggatgcaggc agctaccgct gcgagctggg ctctgtgaat tccagcccag    660

ccacgatcat caattttcac gtcacagtgt tgcccaaaat gatcaaggag gaaaaacctt    720

ctccaaatat cgtaaccccg ggggaggcga ccacggagtc gtccataagc ctccagcctc    780

tgcagcccga gaaaatgctg gcaagccgcc ttctggggct gctgatctgc ggctccctag    840

cactgataac cggccttacc tttgcgatat ttcgtcgaag gaaggtgatc gatttcatca    900

aatcctcact gtttggcctt ggcagtggag cggccgagca aacccaggtc ccaaaagaaa    960

aggccacaga ttcgaggcaa caataaagat ttatcttgtt gtctaa                  1006


<210>  9433
<211>  237
<212>  PRT
<213>  Homo sapiens

<400>  9433

Met Leu His Leu Gln Lys Glu Thr Phe Ala Thr Tyr Val Ala Arg Phe 
1               5                   10                  15


Gln Lys Glu Ala Tyr Cys Pro Asn Lys Cys Gly Val Met Leu Gln Thr 
            20                  25                  30


Leu Ile Trp Cys Lys Asn Cys Lys Lys Glu Val His Ala Cys Arg Lys 
        35                  40                  45


Ser Tyr Asp Cys Gly Glu Arg Asn Val Glu Val Pro Gln Met Glu Asp 
    50                  55                  60


Met Ile Leu Asp Cys Glu Leu Asn Trp His Gln Ala Ser Glu Gly Leu 
65                  70                  75                  80


Thr Asp Tyr Ser Phe Tyr Arg Val Trp Gly Asn Asn Thr Glu Thr Leu 
                85                  90                  95


Val Ser Lys Gly Lys Glu Ala Thr Leu Thr Lys Pro Met Val Gly Pro 
            100                 105                 110


Glu Asp Ala Gly Ser Tyr Arg Cys Glu Leu Gly Ser Val Asn Ser Ser 
        115                 120                 125


Pro Ala Thr Ile Ile Asn Phe His Val Thr Val Leu Pro Lys Met Ile 
    130                 135                 140


Lys Glu Glu Lys Pro Ser Pro Asn Ile Val Thr Pro Gly Glu Ala Thr 
145                 150                 155                 160


Thr Glu Ser Ser Ile Ser Leu Gln Pro Leu Gln Pro Glu Lys Met Leu 
                165                 170                 175


Ala Ser Arg Leu Leu Gly Leu Leu Ile Cys Gly Ser Leu Ala Leu Ile 
            180                 185                 190


Thr Gly Leu Thr Phe Ala Ile Phe Arg Arg Arg Lys Val Ile Asp Phe 
        195                 200                 205


Ile Lys Ser Ser Leu Phe Gly Leu Gly Ser Gly Ala Ala Glu Gln Thr 
    210                 215                 220


Gln Val Pro Lys Glu Lys Ala Thr Asp Ser Arg Gln Gln 
225                 230                 235


<210>  9434
<211>  1621
<212>  DNA
<213>  Homo sapiens

<400>  9434
ggaatatcta taaaggaatt cgggccccta cgtgagaagc tcggaggggg tggtttcagg     60

agttccttgt ggagagggga tcgtccgtga ctcagacccc gtcgaaaagc tctcgatttc    120

acgcaaccaa ccttaccctc gtccccaaca caatccttga ttttacccct gggaaaatta    180

gcgtaggtgg tcatgacccc ggcttcctct ttaaaagccc tcagaacctg gaccgggctc    240

ctcaatgaac cctagtgtta gaggccacaa atcgggaacc aaggtcgggg agcggctgtt    300

tagggtgcat cactgttcag gatgcatcgg ggctcctttt tctaagcgga agggtgcgcc    360

ctgcaaattg ggagcccgtt agttttgggg aagggtgaac aagggccccc taggtctaga    420

ggaccgcatg gagtctcgct taagtgttag tggggtcctc agttctagga atctgcgttc    480

tcctgctctc ggtttggggt gagagcaccc ttcctaacgg tcttcgggaa ctgtgcgcgc    540

cggctgcaat ggggccgcat tttaccctcc tgtgtgcggc gctggccggt tgcttgcttc    600

ctgccgaggg gtgtgttata tgtgacccgt ctgtcgtgct ggcgctaaag tccctggaga    660

aagattacct gcctggccac ctggatgcga agcatcacaa agccatgatg gaaagggtag    720

agaatgccgt gaaggatttc caggaactgt cgcttaatga ggatgcctat atgggggtcg    780

ttgatgaggc cacactgcaa aaggggtcct ggagtttgct gaaggatctg aaacgcatca    840

cagacagtga tgtaaaaggc gatctcttcg tgaaggagct attttggatg ttgcacttgc    900

aaaaggaaac ctttgccacc tatgttgctc gattccaaaa agaggcttat tgtcccaaca    960

aatgtggtgt gatgttgcaa actctgatct ggtgcaagaa ctgcaaaaag gaggttcacg   1020

cttgtcgaaa gtcctacgat tgcggggagc ggaatgtgga agttcctcaa atggaagaca   1080

tgatcctgga ctgtgagtta aactggcatc aggcttcgga aggcctcact gattacagct   1140

tttacagggt ttgggggaac aatacggaga ccttggtgtc caaggggaaa gaggccaccc   1200

tgaccaagcc catggtgggt ccagaggatg caggcagcta ccgctgcgag ctgggctctg   1260

tgaattccag cccagccacg atcatcaatt ttcacgtcac agtgttgccc aaaatgatca   1320

aggaggaaaa accttctcca aatatcgtaa ccccggggga ggcgaccacg gagtcgtcca   1380

taagcctcca gcctctgcag cccgagaaaa tgctggcaag ccgccttctg gggctgctga   1440

tctgcggctc cctagcactg ataaccggcc ttacctttgc gatatttcgt cgaaggaagg   1500

tgatcgattt catcaaatcc tcactgtttg gccttggcag tggagcggcc gagcaaaccc   1560

aggtcccaaa agaaaaggcc acagattcga ggcaacaata aagatttatc ttgttgtcta   1620

a                                                                   1621


<210>  9435
<211>  350
<212>  PRT
<213>  Homo sapiens

<400>  9435

Met Gly Pro His Phe Thr Leu Leu Cys Ala Ala Leu Ala Gly Cys Leu 
1               5                   10                  15


Leu Pro Ala Glu Gly Cys Val Ile Cys Asp Pro Ser Val Val Leu Ala 
            20                  25                  30


Leu Lys Ser Leu Glu Lys Asp Tyr Leu Pro Gly His Leu Asp Ala Lys 
        35                  40                  45


His His Lys Ala Met Met Glu Arg Val Glu Asn Ala Val Lys Asp Phe 
    50                  55                  60


Gln Glu Leu Ser Leu Asn Glu Asp Ala Tyr Met Gly Val Val Asp Glu 
65                  70                  75                  80


Ala Thr Leu Gln Lys Gly Ser Trp Ser Leu Leu Lys Asp Leu Lys Arg 
                85                  90                  95


Ile Thr Asp Ser Asp Val Lys Gly Asp Leu Phe Val Lys Glu Leu Phe 
            100                 105                 110


Trp Met Leu His Leu Gln Lys Glu Thr Phe Ala Thr Tyr Val Ala Arg 
        115                 120                 125


Phe Gln Lys Glu Ala Tyr Cys Pro Asn Lys Cys Gly Val Met Leu Gln 
    130                 135                 140


Thr Leu Ile Trp Cys Lys Asn Cys Lys Lys Glu Val His Ala Cys Arg 
145                 150                 155                 160


Lys Ser Tyr Asp Cys Gly Glu Arg Asn Val Glu Val Pro Gln Met Glu 
                165                 170                 175


Asp Met Ile Leu Asp Cys Glu Leu Asn Trp His Gln Ala Ser Glu Gly 
            180                 185                 190


Leu Thr Asp Tyr Ser Phe Tyr Arg Val Trp Gly Asn Asn Thr Glu Thr 
        195                 200                 205


Leu Val Ser Lys Gly Lys Glu Ala Thr Leu Thr Lys Pro Met Val Gly 
    210                 215                 220


Pro Glu Asp Ala Gly Ser Tyr Arg Cys Glu Leu Gly Ser Val Asn Ser 
225                 230                 235                 240


Ser Pro Ala Thr Ile Ile Asn Phe His Val Thr Val Leu Pro Lys Met 
                245                 250                 255


Ile Lys Glu Glu Lys Pro Ser Pro Asn Ile Val Thr Pro Gly Glu Ala 
            260                 265                 270


Thr Thr Glu Ser Ser Ile Ser Leu Gln Pro Leu Gln Pro Glu Lys Met 
        275                 280                 285


Leu Ala Ser Arg Leu Leu Gly Leu Leu Ile Cys Gly Ser Leu Ala Leu 
    290                 295                 300


Ile Thr Gly Leu Thr Phe Ala Ile Phe Arg Arg Arg Lys Val Ile Asp 
305                 310                 315                 320


Phe Ile Lys Ser Ser Leu Phe Gly Leu Gly Ser Gly Ala Ala Glu Gln 
                325                 330                 335


Thr Gln Val Pro Lys Glu Lys Ala Thr Asp Ser Arg Gln Gln 
            340                 345                 350


<210>  9436
<211>  2204
<212>  DNA
<213>  Homo sapiens

<400>  9436
tggggactta tgagtgattc ctgtttaata gtttttctga tctctcagtt gggggattca     60

gtgagaaccc taaattttgg gtcccctgga ttggggctca gtttcacact tcggaggcat    120

ttgatgaagg acataggtcc tctttatttg gagatttcct gaagatcctc ttttcgaggt    180

ttgcggaccc catggatagg cggcccagtg ggatttctta agatggattt tggcttttct    240

ccgtttagcg ttctcctgct ctcggtttgg ggtgagagca cccttcctaa cggtcttcgg    300

gaactgtgcg cgccggctgc aatggggccg cattttaccc tcctgtgtgc ggcgctggcc    360

ggttgcttgc ttcctgccga ggggtgtgtt atatgtgacc cgtctgtcgt gctggcgcta    420

aagtccctgg agaaagatta cctgcctggc cacctggatg cgaagcatca caaagccatg    480

atggaaaggg tagagaatgc cgtgaaggat ttccaggaac tgtcgcttaa tgaggatgcc    540

tatatggggg tcgttggtga gggcaggggg gaccacggac ccctgggtcc tgggaaagga    600

gggagataag accaggggaa ggaagaggct gacagcaggg tctccgggat tcgggaatgg    660

agaaggctga gatgcagatt ccgaggttcc ccgaggctag taaataccgt tttccctatc    720

ctcggctggc aattttatgt aataaaacta caactcccag aaggcaacgg gcggctgagt    780

ccttaaccag gcctatcttt gcccagtggc ctcatgggta ttgtagtttc taagattagg    840

cgcgccaatg agacagtaag gctggaatct ggggttatat ctcctctgac agatgaggcc    900

acactgcaaa aggggtcctg gagtttgctg aaggatctga aacgcatcac agacagtgat    960

gtaaaaggcg atctcttcgt gaaggagcta ttttggatgt tgcacttgca aaaggaaacc   1020

tttgccacct atgttgctcg attccaaaaa gaggcttatt gtcccaacaa atgtggtgag   1080

tctggattac agaagttaac cctcatcctg ccctctgaat agtcaacctc cccactcgcc   1140

tttttggatc ctggtggttt tgtcattctc tgccttggag aggttcctgg gtctccagta   1200

ttctttctgc accatggatt tcttggggag caggtcatat tctacttaca ctcttttttt   1260

tgagacagtc tcaccctgtc acccaggctg gagtgcagtg gcacgatcac ggctcactgc   1320

aacctccacc tcccaggttc aaactattct cctgcctcag ccccctgagt agctgggatt   1380

acaggtgccc gccatcacac ccagctaatt tttgtatttt tagcagagac ggggtttcac   1440

catgttggtc aggctagtct tgaactcctg accttgtgat ccgcccgcct cggcctccca   1500

aagtgctggg attacaggag taagccaccg catccggcct ctacttacaa tctttactga   1560

gccttgttgg agcccactta ctacttacct gcgtcctggt cctgtgcctt cgtctgacca   1620

tctaggaatg tcatagatga tctggcccca gcccttagcc ctgacctctc cttttagcca   1680

tgccccttag tgggcaaata caagccttga ccctgcccct ccaggtgtga tgttgcaaac   1740

tctgatctgg tgcaagaact gcaaaaagga ggttcacgct tgtcgaaagt cctacgattg   1800

cgggggtgag agaactggac ccagcaggag gaattggtgc aggtggggtg gggcgagagg   1860

agaggcagtc tagagagagc ctagatgggg gtgtgggggc agtagacaag aaaaggtagg   1920

gtttaggcca ggtgcagtgg ttcacaccta tagtctcgca cttcgagagg ctgagacggg   1980

aggattggga agccaggagt ttgagaccag cctgggcaac atagcgagac tctatctcta   2040

caaaaaaatt taaaaattag tcaggtgtgg tgttgcgttc ctgtagtccc agctacttgg   2100

aaggctgagg caggaggatt gcttggaccc aggagttgga gactgcagta agctatgatc   2160

ataccactgc actccagccc aggcaaaaga gtgagacctt gtct                    2204


<210>  9437
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  9437

Met Gly Ile Val Val Ser Lys Ile Arg Arg Ala Asn Glu Thr Val Arg 
1               5                   10                  15


Leu Glu Ser Gly Val Ile Ser Pro Leu Thr Asp Glu Ala Thr Leu Gln 
            20                  25                  30


Lys Gly Ser Trp Ser Leu Leu Lys Asp Leu Lys Arg Ile Thr Asp Ser 
        35                  40                  45


Asp Val Lys Gly Asp Leu Phe Val Lys Glu Leu Phe Trp Met Leu His 
    50                  55                  60


Leu Gln Lys Glu Thr Phe Ala Thr Tyr Val Ala Arg Phe Gln Lys Glu 
65                  70                  75                  80


Ala Tyr Cys Pro Asn Lys Cys Gly Glu Ser Gly Leu Gln Lys Leu Thr 
                85                  90                  95


Leu Ile Leu Pro Ser Glu 
            100


<210>  9438
<211>  221
<212>  DNA
<213>  Homo sapiens

<400>  9438
tcgatttcac gcaaccaacc ttaccctcgt ccccaacaca atccttgatt ttacccctgg     60

gaaaattagc atgaggccac actgcaaaag gggtcctgga gtttgctgaa ggatctgaaa    120

cgcatcacag acagtgatgt aaaaggcgat ctcttcgtga aggagctatt ttggatgttg    180

cacttgcaaa aggaaacctt tgccacctat gttgctcgat t                        221


<210>  9439
<211>  4246
<212>  DNA
<213>  Homo sapiens

<400>  9439
gaaagtccct gactggagtt ggcagccaag ccaggccctg gagtgggcac ccagagggaa     60

gacaggttgg ctaatttcct ggagccccta agggtgcaag ggggaagaac acccacccgc    120

aaagccccgt agggctggac cctacgttag cctgccctgc tcggggttgg cgatgctgga    180

ggtgggcctt ggaccagaga aaatgcttta attaggtgac aagcgggcag aggcctttgt    240

ctctggcgcc ggcagccacg gcccccgctg acggcgtggg aaacagaccc tgttccactc    300

cggtctccag ccttggaatg gttgccttcg tgcagtgcag gaggacgcgg cagagggcgg    360

acgatcgctc cactcgccgg gaccaggtgc gggggccctg cccagccgct ggggcgtggc    420

caggctcgaa gcacccaggt gtcgggggcc gactctaagc cctggcaccg gaagagagag    480

ggcggcggat tggacctccc ggctccagca ttgcaactgg gcgctccgtc tcctggtcca    540

cgcaatgatg ctgcggctgc tcagaagcca ggtagcctgc cctgggtgaa gccttcgcgc    600

aggtcaatga cggggcggag gggcagggcg cggtcccctg catccccgat ctggggagcg    660

gtgggcccag gggccatcgc cttagcccct ggcgctgggg ctcggcgcca agtgacgggc    720

ggggctccac cttccagcca tccgcccggc ccgggagggc ggacgctgcg agactcccgg    780

ccgcgccctc tccttcctct cctccccaag ccctcgctgc cagtccggac aggctgcgcg    840

gaggggaggg ctgccgggcc ggatagccgg acgcctggcg ttccaggggc ggccggatgt    900

ggcctgcctt tgcggagggt gcgctccggc cacgaaaagc ggactgtgga tctgccacct    960

gcaagcagct cggccatgtg gctccggagc catcgtcagc tctgcctggc cttcctgcta   1020

gtctgtgtcc tctctgtaat cttcttcctc catatccatc aagacagctt tccacatggc   1080

ctaggcctgt cgatcctgtg tccagaccgc cgcctggtga cacccccagt ggccatcttc   1140

tgcctgccgg gtactgcgat gggccccaac gcctcctctt cctgtcccca gcaccctgct   1200

tccctctccg gcacctggac tgtctacccc aatggccggt ttggtaatca gatgggacag   1260

tatgccacgc tgctggctct ggcccagctc aacggccgcc gggcctttat cctgcctgcc   1320

atgcatgccg ccctggcccc ggtattccgc atcaccctgc ccgtgctggc cccagaagtg   1380

gacagccgca cgccgtggcg ggagctgcag cttcacgact ggatgtcgga ggagtacgcg   1440

gacttgagag atcctttcct gaagctctct ggcttcccct gctcttggac tttcttccac   1500

catctccggg aacagatccg cagagagttc accctgcacg accaccttcg ggaagaggcg   1560

cagagtgtgc tgggtcagct ccgcctgggc cgcacagggg accgcccgcg cacctttgtc   1620

ggcgtccacg tgcgccgtgg ggactatctg caggttatgc ctcagcgctg gaagggtgtg   1680

gtgggcgaca gcgcctacct ccggcaggcc atggactggt tccgggcacg gcacgaagcc   1740

cccgttttcg tggtcaccag caacggcatg gagtggtgta aagaaaacat cgacacctcc   1800

cagggcgatg tgacgtttgc tggcgatgga caggaggcta caccgtggaa agactttgcc   1860

ctgctcacac agtgcaacca caccattatg accattggca ccttcggctt ctgggctgcc   1920

tacctggctg gcggagacac tgtctacctg gccaacttca ccctgccaga ctctgagttc   1980

ctgaagatct ttaagccgga ggcggccttc ctgcccgagt gggtgggcat taatgcagac   2040

ttgtctccac tctggacatt ggctaagcct tgagagccag ggagactttc tgaagtagcc   2100

tgatctttct agagccagca gtacgtggct tcagaggcct ggcatcttct ggagaagctt   2160

gtggtgttcc tgaagcaaat gggtgcccgt atccagagtg attctagttg ggagagttgg   2220

agagaagggg gacgtttctg gaactgtctg aatattctag aactagcaaa acatcttttc   2280

ctgatggctg gcaggcagtt ctagaagcca cagtgcccac ctgctcttcc cagcccatat   2340

ctacagtact tccagatggc tgcccccagg aatggggaac tctccctctg gtctactcta   2400

gaagaggggt tacttctccc ctgggtcctc caaagactga aggagcatat gattgctcca   2460

gagcaagcat tcaccaagtc cccttctgtg tttctggagt gattctagag ggagacttgt   2520

tctagagagg accaggtttg atgcctgtga agaaccctgc agggccctta tggacaggat   2580

ggggttctgg aaatccagat aactaaggtg aagaatcttt ttagtttttt tttttttttt   2640

ttggagacag ggtctcgctc tgttgcccag gctggagtgc agtggcgtga tcttggctca   2700

ctgcaacttc cgcctcctgt gttcaagcga ttctcctgtc tcagcctcct gagtagatgg   2760

gactacaggc acaggccatt atgcctggct aatttttgta tttttagtag agacagggtt   2820

tcaccatgtt ggccaggatg gtctcgatct cctgaccttg tcatccacct gtcttggcct   2880

cccaaagtgc tgggattact ggcatgagcc actgtgccca gcccggatat ttttttttta   2940

attatttatt tatttattta tttattgaga cggagtcttg ctctgtagcc caggccagag   3000

tgcagtggcg cgatctcagc tcactgcaag ctctgcctcc cgggttcatg ccattctgcc   3060

tcagcctcct gagtagctgg gactacaggc gcccgccacc acgcccggct aatttttttt   3120

gtatttttag tagagacggg gtttcatcgt gttaaccagg atggtctcga tctcctgacc   3180

tcgtgatctg cccacctcgg cctcccacag tgctgggatt accggcgtga gccaccatgc   3240

ctggcccgga taattttttt taatttttgt agagacgagg tcttgtgata ttgcccaggc   3300

tgttcttcaa ctcctgggct caagcagtcc tcccaccttg gcctcccaga atgctgggtt   3360

tatagatgtg agccagcaca ccgggccaag tgaagaatct aatgaatgtg caacctaatt   3420

gtagcatcta atgaatgttc caccattgct ggaaaaattg agatggaaaa caaaccatct   3480

ctagttggcc agcgtcttgc tctgttcaca gtctctggaa aagctggggt agttggtgag   3540

cagagcggga ctctgtccaa caagccccac agcccctcaa agactttttt ttgtttgttt   3600

tgagcagaca ggctaaaatg tgaacgtggg gtgagggatc actgccaaaa tggtacagct   3660

tctggagcag aactttccag ggatccaggg acactttttt ttaaagctca taaactgcca   3720

agagctccat atattgggtg tgagttcagg ttgcctctca caatgaagga agttggtctt   3780

tgtctgcagg tgggctgctg agggtctggg atctgttttc tggaagtgtg caggtataaa   3840

cacaccctct gtgcttgtga caaactggca ggtaccgtgc tcattgctaa ccactgtctg   3900

tccctgaact cccagaacca ctacatctgg ctttgggcag gtctgagata aaacgatcta   3960

aaggtaggca gaccctggac ccagcctcag atccaggcag gagcacgagg tctggccaag   4020

gtggacgggg ttgtcgagat ctcaggagcc ccttgctgtt ttttggaggg tgaaagaaga   4080

aaccttaaac atagtcagct ctgatcacat cccctgtcta ctcatccaga ccccatgcct   4140

gtaggcttat cagggagtta cagttacaat tgttacagta ctgttcccaa ctcagctgcc   4200

acgggtgaga gagcaggagg tatgaattaa aagtctacag cactaa                  4246


<210>  9440
<211>  488
<212>  PRT
<213>  Homo sapiens

<400>  9440

Met Thr Gly Arg Arg Gly Arg Ala Arg Ser Pro Ala Ser Pro Ile Trp 
1               5                   10                  15


Gly Ala Val Gly Pro Gly Ala Ile Ala Leu Ala Pro Gly Ala Gly Ala 
            20                  25                  30


Arg Arg Gln Val Thr Gly Gly Ala Pro Pro Ser Ser His Pro Pro Gly 
        35                  40                  45


Pro Gly Gly Arg Thr Leu Arg Asp Ser Arg Pro Arg Pro Leu Leu Pro 
    50                  55                  60


Leu Leu Pro Lys Pro Ser Leu Pro Val Arg Thr Gly Cys Ala Glu Gly 
65                  70                  75                  80


Arg Ala Ala Gly Pro Asp Ser Arg Thr Pro Gly Val Pro Gly Ala Ala 
                85                  90                  95


Gly Cys Gly Leu Pro Leu Arg Arg Val Arg Ser Gly His Glu Lys Arg 
            100                 105                 110


Thr Val Asp Leu Pro Pro Ala Ser Ser Ser Ala Met Trp Leu Arg Ser 
        115                 120                 125


His Arg Gln Leu Cys Leu Ala Phe Leu Leu Val Cys Val Leu Ser Val 
    130                 135                 140


Ile Phe Phe Leu His Ile His Gln Asp Ser Phe Pro His Gly Leu Gly 
145                 150                 155                 160


Leu Ser Ile Leu Cys Pro Asp Arg Arg Leu Val Thr Pro Pro Val Ala 
                165                 170                 175


Ile Phe Cys Leu Pro Gly Thr Ala Met Gly Pro Asn Ala Ser Ser Ser 
            180                 185                 190


Cys Pro Gln His Pro Ala Ser Leu Ser Gly Thr Trp Thr Val Tyr Pro 
        195                 200                 205


Asn Gly Arg Phe Gly Asn Gln Met Gly Gln Tyr Ala Thr Leu Leu Ala 
    210                 215                 220


Leu Ala Gln Leu Asn Gly Arg Arg Ala Phe Ile Leu Pro Ala Met His 
225                 230                 235                 240


Ala Ala Leu Ala Pro Val Phe Arg Ile Thr Leu Pro Val Leu Ala Pro 
                245                 250                 255


Glu Val Asp Ser Arg Thr Pro Trp Arg Glu Leu Gln Leu His Asp Trp 
            260                 265                 270


Met Ser Glu Glu Tyr Ala Asp Leu Arg Asp Pro Phe Leu Lys Leu Ser 
        275                 280                 285


Gly Phe Pro Cys Ser Trp Thr Phe Phe His His Leu Arg Glu Gln Ile 
    290                 295                 300


Arg Arg Glu Phe Thr Leu His Asp His Leu Arg Glu Glu Ala Gln Ser 
305                 310                 315                 320


Val Leu Gly Gln Leu Arg Leu Gly Arg Thr Gly Asp Arg Pro Arg Thr 
                325                 330                 335


Phe Val Gly Val His Val Arg Arg Gly Asp Tyr Leu Gln Val Met Pro 
            340                 345                 350


Gln Arg Trp Lys Gly Val Val Gly Asp Ser Ala Tyr Leu Arg Gln Ala 
        355                 360                 365


Met Asp Trp Phe Arg Ala Arg His Glu Ala Pro Val Phe Val Val Thr 
    370                 375                 380


Ser Asn Gly Met Glu Trp Cys Lys Glu Asn Ile Asp Thr Ser Gln Gly 
385                 390                 395                 400


Asp Val Thr Phe Ala Gly Asp Gly Gln Glu Ala Thr Pro Trp Lys Asp 
                405                 410                 415


Phe Ala Leu Leu Thr Gln Cys Asn His Thr Ile Met Thr Ile Gly Thr 
            420                 425                 430


Phe Gly Phe Trp Ala Ala Tyr Leu Ala Gly Gly Asp Thr Val Tyr Leu 
        435                 440                 445


Ala Asn Phe Thr Leu Pro Asp Ser Glu Phe Leu Lys Ile Phe Lys Pro 
    450                 455                 460


Glu Ala Ala Phe Leu Pro Glu Trp Val Gly Ile Asn Ala Asp Leu Ser 
465                 470                 475                 480


Pro Leu Trp Thr Leu Ala Lys Pro 
                485


<210>  9441
<211>  431
<212>  DNA
<213>  Homo sapiens

<400>  9441
tcggcttctg ggctgcctac ctggctggcg gagacactgt ctacctggcc aatggcaggt     60

accgtgctca ttgctaacca ctgtctgtcc ctgaactccc agaaccacta catctggctt    120

tgggcaggtc tgagataaaa cgatctaaag gtaggcagac cctggaccca gcctcagatc    180

caggcaggag cacgaggtct ggccaaggtg gacggggttg tcgagatctc aggagcccct    240

tgctgttttt tggagggtga aagaagaaac cttaaacata gtcagctctg atcacatccc    300

ctgtctactc atccagaccc catgcctgta ggcttatcag ggagttacag ttacaattgt    360

tacagtactg ttcccaactc agctgccacg ggtgagagag caggaggtat gaattaaaag    420

tctacagcac t                                                         431


<210>  9442
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9442

Met Pro Val Gly Leu Ser Gly Ser Tyr Ser Tyr Asn Cys Tyr Ser Thr 
1               5                   10                  15


Val Pro Asn Ser Ala Ala Thr Gly Glu Arg Ala Gly Gly Met Asn 
            20                  25                  30


<210>  9443
<211>  597
<212>  DNA
<213>  Homo sapiens

<400>  9443
ctgcgtcttg atggggaaga acacccaccc gcaaagcccc gtagggctgg accctacgtt     60

agcctgccct gctcggggtt ggcgatgctg gaggtgggcc ttggaccaga gaaaatgctt    120

taattaggtg acaagcgggc agaggccttt gtctctggcg ccggcagcca cggcccccgc    180

tgacggcgtg ggaaacagac cctgttccac tccggtctcc agccttggaa tggttgcctt    240

cgtgcagtgc aggaggacgc ggcagagggc ggacgatcgc tccactcgcc gggaccaggt    300

gcgggggccc tgcccagccg ctggggcgtg gccaggctcg aagcacccag gtgtcggggg    360

ccgactctaa gccctggcac cggaagagag agggcggcgg attggacctc ccggctccag    420

cattgcaact gggcgctccg tctcctggtc cacgcaatga tgctgcggct gctcagaagc    480

cagccatccg cccggcccgg gagggcggac gctgcgagac tcccggccgc gccctctcct    540

tcctctcctc cccaagccct cgctgccagt ccggacaggc tgcgcggagg ggagggc       597


<210>  9444
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  9444

Met Met Leu Arg Leu Leu Arg Ser Gln Pro Ser Ala Arg Pro Gly Arg 
1               5                   10                  15


Ala Asp Ala Ala Arg Leu Pro Ala Ala Pro Ser Pro Ser Ser Pro Pro 
            20                  25                  30


Gln Ala Leu Ala Ala Ser Pro Asp Arg Leu Arg Gly Gly Glu 
        35                  40                  45


<210>  9445
<211>  681
<212>  DNA
<213>  Homo sapiens

<400>  9445
ctgcgtcttg atggtagtgg tcccccgggc ccagctgttt tctctttatc tctttgtctt     60

gtgtctttat ttcttacaat ctctcctctc ctcacagggg aagaacaccc acccgcaaag    120

ccccgtaggg ctggacccta cgttagcctg ccctgctcgg ggttggcgat gctggaggtg    180

ggccttggac cagagaaaat gctttaatta ggtgacaagc gggcagaggc ctttgtctct    240

ggcgccggca gccacggccc ccgctgacgg cgtgggaaac agaccctgtt ccactccggt    300

ctccagcctt ggaatggttg ccttcgtgca gtgcaggagg acgcggcaga gggcggacga    360

tcgctccact cgccgggacc aggtgcgggg gccctgccca gccgctgggg cgtggccagg    420

ctcgaagcac ccaggtgtcg ggggccgact ctaagccctg gcaccggaag agagagggcg    480

gcggattgga cctcccggct ccagcattgc aactgggcgc tccgtctcct ggtccacgca    540

atgatgctgc ggctgctcag aagccagcca tccgcccggc ccgggagggc ggacgctgcg    600

agactcccgg ccgcgccctc tccttcctct cctccccaag ccctcgctgc cagtccggac    660

aggctgcgcg gaggggaggg c                                              681


<210>  9446
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  9446

Met Met Leu Arg Leu Leu Arg Ser Gln Pro Ser Ala Arg Pro Gly Arg 
1               5                   10                  15


Ala Asp Ala Ala Arg Leu Pro Ala Ala Pro Ser Pro Ser Ser Pro Pro 
            20                  25                  30


Gln Ala Leu Ala Ala Ser Pro Asp Arg Leu Arg Gly Gly Glu 
        35                  40                  45


<210>  9447
<211>  649
<212>  DNA
<213>  Homo sapiens

<400>  9447
gaaagtccct gactggagtt ggcagccaag ccaggccctg gagtgggcac ccagagggaa     60

gacaggggaa gaacacccac ccgcaaagcc ccgtagggct ggaccctacg ttagcctgcc    120

ctgctcgggg ttggcgatgc tggaggtggg ccttggacca gagaaaatgc tttaattagg    180

tgacaagcgg gcagaggcct ttgtctctgg cgccggcagc cacggccccc gctgacggcg    240

tgggaaacag accctgttcc actccggtct ccagccttgg aatggttgcc ttcgtgcagt    300

gcaggaggac gcggcagagg gcggacgatc gctccactcg ccgggaccag gtgcgggggc    360

cctgcccagc cgctggggcg tggccaggct cgaagcaccc aggtgtcggg ggccgactct    420

aagccctggc accggaagag agagggcggc ggattggacc tcccggctcc agcattgcaa    480

ctgggcgctc cgtctcctgg tccacgcaat gatgctgcgg ctgctcagaa gccagccatc    540

cgcccggccc gggagggcgg acgctgcgag actcccggcc gcgccctctc cttcctctcc    600

tccccaagcc ctcgctgcca gtccggacag gctgcgcgga ggggagggc                649


<210>  9448
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  9448

Met Met Leu Arg Leu Leu Arg Ser Gln Pro Ser Ala Arg Pro Gly Arg 
1               5                   10                  15


Ala Asp Ala Ala Arg Leu Pro Ala Ala Pro Ser Pro Ser Ser Pro Pro 
            20                  25                  30


Gln Ala Leu Ala Ala Ser Pro Asp Arg Leu Arg Gly Gly Glu 
        35                  40                  45


<210>  9449
<211>  1310
<212>  DNA
<213>  Homo sapiens

<400>  9449
gaggcttcca aggcaggata cttgtgtctc agatgcggtc gcttctttca tacagcaatt     60

gccgccttgc tgaggatcaa ggaacctcag tgtcagatca cgccctcccc ccaaacttag    120

aaattcagat ggggcgcaga aatttctctt gttctgcgtg atctgcatag atggtccaag    180

aggtggtttt tccaggagcc cagcacccct cctccctccg actcagaccc aggagtctgg    240

ccctccattg aaaggacccc aggttacatc atccattcag gctgcccttg ccacgatgga    300

attctgtagc tcctgccaaa tgggtcaaat atcatggttc aggcgcaggg agggtgattg    360

ggcgggcctg tctgggtata aattctggag cttctgcatc tatcccaaaa aacaagggtg    420

ttctgtcagc tgaggatcca gccgaaagag gagccaggca ctcaggccac ctgagtctac    480

tcacctggac aactggaatc tggcaccaat tctaaaccac tcagcttctc cgagctcaca    540

ccccggagat cacctgagga cccgagccat tgatggactc ggacgagacc gggttcgagc    600

actcaggact gtgggtttct gtgctggctg gtcttctgct gggagcctgc caggcacacc    660

ccatccctga ctccagtcct ctcctgcaat tcgggggcca agtccggcag cggtacctct    720

acacagatga tgcccagcag acagaagccc acctggagat cagggaggat gggacggtgg    780

ggggcgctgc tgaccagagc cccgaaagtc tcctgcagct gaaagccttg aagccgggag    840

ttattcaaat cttgggagtc aagacatcca ggttcctgtg ccagcggcca gatggggccc    900

tgtatggatc gctccacttt gaccctgagg cctgcagctt ccgggagctg cttcttgagg    960

acggatacaa tgtttaccag tccgaagccc acggcctccc gctgcacctg ccagggaaca   1020

agtccccaca ccgggaccct gcaccccgag gaccagctcg cttcctgcca ctaccaggcc   1080

tgccccccgc actcccggag ccacccggaa tcctggcccc ccagcccccc gatgtgggct   1140

cctcggaccc tctgagcatg gtgggacctt cccagggccg aagccccagc tacgcttcct   1200

gaagccagag gctgtttact atgacatctc ctctttattt attaggttat ttatcttatt   1260

tattttttta tttttcttac ttgagataat aaagagttcc agaggaggat              1310


<210>  9450
<211>  209
<212>  PRT
<213>  Homo sapiens

<400>  9450

Met Asp Ser Asp Glu Thr Gly Phe Glu His Ser Gly Leu Trp Val Ser 
1               5                   10                  15


Val Leu Ala Gly Leu Leu Leu Gly Ala Cys Gln Ala His Pro Ile Pro 
            20                  25                  30


Asp Ser Ser Pro Leu Leu Gln Phe Gly Gly Gln Val Arg Gln Arg Tyr 
        35                  40                  45


Leu Tyr Thr Asp Asp Ala Gln Gln Thr Glu Ala His Leu Glu Ile Arg 
    50                  55                  60


Glu Asp Gly Thr Val Gly Gly Ala Ala Asp Gln Ser Pro Glu Ser Leu 
65                  70                  75                  80


Leu Gln Leu Lys Ala Leu Lys Pro Gly Val Ile Gln Ile Leu Gly Val 
                85                  90                  95


Lys Thr Ser Arg Phe Leu Cys Gln Arg Pro Asp Gly Ala Leu Tyr Gly 
            100                 105                 110


Ser Leu His Phe Asp Pro Glu Ala Cys Ser Phe Arg Glu Leu Leu Leu 
        115                 120                 125


Glu Asp Gly Tyr Asn Val Tyr Gln Ser Glu Ala His Gly Leu Pro Leu 
    130                 135                 140


His Leu Pro Gly Asn Lys Ser Pro His Arg Asp Pro Ala Pro Arg Gly 
145                 150                 155                 160


Pro Ala Arg Phe Leu Pro Leu Pro Gly Leu Pro Pro Ala Leu Pro Glu 
                165                 170                 175


Pro Pro Gly Ile Leu Ala Pro Gln Pro Pro Asp Val Gly Ser Ser Asp 
            180                 185                 190


Pro Leu Ser Met Val Gly Pro Ser Gln Gly Arg Ser Pro Ser Tyr Ala 
        195                 200                 205


Ser 



<210>  9451
<211>  2707
<212>  DNA
<213>  Homo sapiens

<400>  9451
cacagcagcc cccgcgcccg ccgtgccgcc gccgggacgt ggggcccttg ggccgtcggg     60

ccgcctgggg agcgccagcc cggatccggc tgcccagatg cgggcgccac tctgcctgct    120

cctgctcgtc gcccacgccg tggacatgct cgccctgaac cgaaggaaga agcaagtggg    180

cactggcctg gggggcaact gcacaggctg tatcatctgc tcagaggaga acggctgttc    240

cacctgccag cagaggctct tcctgttcat ccgccgggaa ggcatccgcc agtacggcaa    300

gtgcctgcac gactgtcccc ctgggtactt cggcatccgc ggccaggagg tcaacaggtg    360

caaaaaatgt ggggccactt gtgagagctg cttcagccag gacttctgca tccggtgcaa    420

gaggcagttt tacttgtaca aggggaagtg tctgcccacc tgcccgccgg gcactttggc    480

ccaccagaac acacgggagt gccaggggga gtgtgaactg ggtccctggg gcggctggag    540

cccctgcaca cacaatggaa agacctgcgg ctcggcttgg ggcctggaga gccgggtacg    600

agaggctggc cgggctgggc atgaggaggc agccacctgc caggtgcttt ctgagtcaag    660

gaaatgtccc atccagaggc cctgcccagg agagaggagc cccggccaga agaagggcag    720

gaaggaccgg cgcccacgca aggacaggaa gctggaccgc aggctggacg tgaggccgcg    780

ccagcccggc ctgcagccct gaccgccggc tctcccgact ctctggtcct agtcctcggc    840

ccctgcacac ctcctcctgc tccttctcct cctctcctct tactctttct cctctgtctt    900

ctccatttgt cctctctttc tttccaccct tctatcattt ttctgtcagt ctaccttccc    960

tttctttttc ttttttattt cctttatttc ttccacctcc attctcctct cctttctccc   1020

tccctccttc ccttccttcc tcttctttct cacttatctt ttatctttcc ttttctttct   1080

tcctgtgttt cttcctgtcc ttcaccgcat ccttctctct ctccctcctc ttgtctccct   1140

ctcacacaca ctttaagagg gaccatgagc ctgtgccctc ccctgcagct ttctctatct   1200

acaacttaaa gaaagcaaac atcttttccc aggcctttcc ctgaccccat ctttgcagag   1260

aaagggtttc cagagggcaa agctgggaca cagcacaggt gaatcctgaa ggccctgctt   1320

ctgctctggg ggaggctcca ggaccctgag ctgtgagcac ctggttctct ggacagtccc   1380

cagaggccat ttccacagcc ttcagccacc agccaccccg aggagctggc tggacaaggc   1440

tccagggctt ccagaggcct ggcttggaca cctcccccag ctggccgtgg agggtcacaa   1500

cctggcctct gggtgggcag ccagccctgg agggcatcct ctgcaagctg cctgccaccc   1560

tcatcggcac tcccccacag gcctccctct catgggttcc atgccccttt ttcccaagcc   1620

ggatcaggtg agctgtcact gctgggggat ccacctgccc agcccagaag aggccactga   1680

aacggaaagg aaagctgaga ttatccagca gctctgttcc ccacctcagc gcttcctgcc   1740

catgtgggga aacaggtctg agaaggaagg ggcttgccca gggtcacaca ggaagccttc   1800

aggctctgct tctgcctgat ggctctgctc agcacattca cggtggagag gagaatttgg   1860

gggtcacttg aggggggaaa tgtagggaat tgtgggtggg gagcaaggga agatccgtgc   1920

actcgtccac acccaccacc acactcgctg acacccaccc ccacacgctg acacccaccc   1980

ccacacttgc ccacacccat caccgcactc gcccacaccc accaccacac tgccccacac   2040

ccaccaccac actcccccac acccaccacc acactcgccc acacccacca ccagtgactt   2100

gagcatctgt gcttcgctgt gacgcccctc gccctaggca ggaacgacgc tgggaggagt   2160

ctccaggtca gacccagctt ggaagcaagt ctgtcctcac tgcctatcct tctgccatca   2220

taacaccccc ttcctgctct gctccccgga atcctcagaa acgggatttg tatttgccgt   2280

gactggttgg cctgaacacg tagggctccg tgactgggac aggaatgggc aggagaagca   2340

agagtcggag ctccaagggg cccaggggtg gcctggggaa ggaagatggt cagcaggctg   2400

ggggagaggc tctaggtgat gaaatattac attcccgacc ccaagagagc acccaccctc   2460

agacctgccc tccacctggc agctggggag ccctggcctg aacccccccc tcccagcagg   2520

cccaccctct ctctgacttc cctgctctca cctccccgag aacagctaga gccccctcct   2580

ccgcctggcc aggccaccag cttctcttct gcaaacgttt gtgcctctga aatgctccgt   2640

tgttattgtt tcaagaccct aacttttttt taaaactttc ttaataaagg gaaaagaaac   2700

ttgtaaa                                                             2707


<210>  9452
<211>  234
<212>  PRT
<213>  Homo sapiens

<400>  9452

Met Arg Ala Pro Leu Cys Leu Leu Leu Leu Val Ala His Ala Val Asp 
1               5                   10                  15


Met Leu Ala Leu Asn Arg Arg Lys Lys Gln Val Gly Thr Gly Leu Gly 
            20                  25                  30


Gly Asn Cys Thr Gly Cys Ile Ile Cys Ser Glu Glu Asn Gly Cys Ser 
        35                  40                  45


Thr Cys Gln Gln Arg Leu Phe Leu Phe Ile Arg Arg Glu Gly Ile Arg 
    50                  55                  60


Gln Tyr Gly Lys Cys Leu His Asp Cys Pro Pro Gly Tyr Phe Gly Ile 
65                  70                  75                  80


Arg Gly Gln Glu Val Asn Arg Cys Lys Lys Cys Gly Ala Thr Cys Glu 
                85                  90                  95


Ser Cys Phe Ser Gln Asp Phe Cys Ile Arg Cys Lys Arg Gln Phe Tyr 
            100                 105                 110


Leu Tyr Lys Gly Lys Cys Leu Pro Thr Cys Pro Pro Gly Thr Leu Ala 
        115                 120                 125


His Gln Asn Thr Arg Glu Cys Gln Gly Glu Cys Glu Leu Gly Pro Trp 
    130                 135                 140


Gly Gly Trp Ser Pro Cys Thr His Asn Gly Lys Thr Cys Gly Ser Ala 
145                 150                 155                 160


Trp Gly Leu Glu Ser Arg Val Arg Glu Ala Gly Arg Ala Gly His Glu 
                165                 170                 175


Glu Ala Ala Thr Cys Gln Val Leu Ser Glu Ser Arg Lys Cys Pro Ile 
            180                 185                 190


Gln Arg Pro Cys Pro Gly Glu Arg Ser Pro Gly Gln Lys Lys Gly Arg 
        195                 200                 205


Lys Asp Arg Arg Pro Arg Lys Asp Arg Lys Leu Asp Arg Arg Leu Asp 
    210                 215                 220


Val Arg Pro Arg Gln Pro Gly Leu Gln Pro 
225                 230


<210>  9453
<211>  722
<212>  DNA
<213>  Homo sapiens

<400>  9453
gcccacagca gcccccgcgc ccgccgtgcc gccgccggga cgtggggccc ttgggccgtc     60

gggccgcctg gggagcgcca gcccggatcc ggctgcccag atgcgggcgc cactctgcct    120

gctcctgctc gtcgcccacg ccgtggacat gctcgccctg aaccgaagga agaagcaagt    180

gggcactggc ctggggggca actgcacagg ctgtatcatc tgctcagagg agaacggctg    240

ttccacctgc cagcagaggc tcttcctgtt catccgccgg gaaggcatcc gccagtacgg    300

caagtgcctg cacgactgtc cccctgggta cttcggcatc cgcggccagg aggtcaacag    360

gtgcaaaaaa tgtggggcca cttgtgagag ctgcttcagc caggacttct gcatccggtg    420

caagaggcag ttttacttgt acaaggggaa gtgtctgccc acctgcccgc cgggcacttt    480

ggcccaccag aacacacggg agtgccagga gaggagcccc ggccagaaga agggcaggaa    540

ggaccggcgc ccacgcaagg acaggaagct ggaccgcagg ctggacgtga ggccgcgcca    600

gcccggcctg cagccctgac cgccggctct cccgactctc tggtcctagt cctcggcccc    660

tgcacacctc ctcctgctcc ttctcctcct ctcctcttac tctttctcct ctgtcttctc    720

ca                                                                   722


<210>  9454
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  9454

Met Arg Ala Pro Leu Cys Leu Leu Leu Leu Val Ala His Ala Val Asp 
1               5                   10                  15


Met Leu Ala Leu Asn Arg Arg Lys Lys Gln Val Gly Thr Gly Leu Gly 
            20                  25                  30


Gly Asn Cys Thr Gly Cys Ile Ile Cys Ser Glu Glu Asn Gly Cys Ser 
        35                  40                  45


Thr Cys Gln Gln Arg Leu Phe Leu Phe Ile Arg Arg Glu Gly Ile Arg 
    50                  55                  60


Gln Tyr Gly Lys Cys Leu His Asp Cys Pro Pro Gly Tyr Phe Gly Ile 
65                  70                  75                  80


Arg Gly Gln Glu Val Asn Arg Cys Lys Lys Cys Gly Ala Thr Cys Glu 
                85                  90                  95


Ser Cys Phe Ser Gln Asp Phe Cys Ile Arg Cys Lys Arg Gln Phe Tyr 
            100                 105                 110


Leu Tyr Lys Gly Lys Cys Leu Pro Thr Cys Pro Pro Gly Thr Leu Ala 
        115                 120                 125


His Gln Asn Thr Arg Glu Cys Gln Glu Arg Ser Pro Gly Gln Lys Lys 
    130                 135                 140


Gly Arg Lys Asp Arg Arg Pro Arg Lys Asp Arg Lys Leu Asp Arg Arg 
145                 150                 155                 160


Leu Asp Val Arg Pro Arg Gln Pro Gly Leu Gln Pro 
                165                 170


<210>  9455
<211>  722
<212>  DNA
<213>  Homo sapiens

<400>  9455
ggcaaccagg aactggtggc tgcagccacc agccaagttc tttccatcat cctgggccct     60

cacctctggc ataggctctt ggtagtgggg gcccagacag ggaggcacct gccacctgct    120

tcccttctca gccacccaca gccctcatag ggcagaatgg gactcttgct gatgtagacg    180

ccgaagtcgc gggcgctcat ggcgggcctg gaggtactgt tcgcatcggc agcgccggcc    240

atcacctgca ggcaggacgc gctcgtctgc ttcttgcatt gggaagtggt gacacacggt    300

tacttcggct tgggtgtcgg tgaccagccg ggtcccaatg ataagaagtc agaactgctg    360

ccagctgggt ggaacaacaa taaagacctg tatgtcctcc ggtatgagta taaggatggg    420

tccagaaagc tccttgtgaa agccatcacc gtggagagca gcatgatcct caatgtgctg    480

gaatatggct cacagcaagt ggcagacttg accctgaact tggatgatta tatcgatgca    540

gaacacctgg gtgacttcca caggacctac aagaacagtg aggagcttcg gtctcgtatt    600

gtgtctggaa tcatcacacc tatccatgag cagtgggaaa aggctaatgt aagcagtccc    660

caccgggagt tcccccctgc taccgccaga gaggtggacc cactccggat tcctccacac    720

ca                                                                   722


<210>  9456
<211>  173
<212>  PRT
<213>  Homo sapiens

<400>  9456

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro 
                165                 170


<210>  9457
<211>  3262
<212>  DNA
<213>  Homo sapiens

<400>  9457
ggcaaccagg aactggtggc tgcagccacc agccaagttc tttccatcat cctgggccct     60

cacctctggc ataggctctt ggtagtgggg gcccagacag ggaggcacct gccacctgct    120

tcccttctca gccacccaca gccctcatag ggcagaatgg gactcttgct gatgtagacg    180

ccgaagtcgc gggcgctcat ggcgggcctg gaggtactgt tcgcatcggc agcgccggcc    240

atcacctgca ggcaggacgc gctcgtctgc ttcttgcatt gggaagtggt gacacacggt    300

tacttcggct tgggtgtcgg tgaccagccg ggtcccaatg ataagaagtc agaactgctg    360

ccagctgggt ggaacaacaa taaagacctg tatgtcctcc ggtatgagta taaggatggg    420

tccagaaagc tccttgtgaa agccatcacc gtggagagca gcatgatcct caatgtgctg    480

gaatatggct cacagcaagt ggcagacttg accctgaact tggatgatta tatcgatgca    540

gaacacctgg gtgacttcca caggacctac aagaacagtg aggagcttcg gtctcgtatt    600

gtgtctggaa tcatcacacc tatccatgag cagtgggaaa aggctaatgt aagcagtccc    660

caccgggagt tcccccctgc taccgccaga gaggtggacc cactccggat tcctccacac    720

cacccacaca ccagtcggca gcctccctgg tgtgatcccc tgggcccgtt tgttgtcggg    780

ggagaagact tagacccttt tgggcctcgg agaggtggca tgattgtgga tcccctgaga    840

tctggcttcc caagagcact tattgaccct tcctcaggcc tcccgaaccg acttcctcca    900

ggcgctgtgc ccccaggagc tcgctttgac ccctttggac ccattgggac cagcccaccc    960

ggacctaacc cagaccatct ccccccgccg ggctacgatg acatgtacct gtgaaggcct   1020

caagaatgta acatcccagg cttccctcca ttctcctgga gctgccaccg ctgtccccat   1080

cagcaaccat gttcttgcag gctgggggca agggattctg ctcatgtgtt tgcagaccgg   1140

ctgggatagc ctccccaccc cttatcagag ccaagacacc tgctgcagct ctccacctag   1200

ctgcagatag ctcccaaaga gaaatcagtg tgtctctttc accatcagct cctccccttt   1260

caccaccagc tcctctccac ttcccaaggg agactccggc aaccttcagc aacatatatc   1320

ctcgaccaga tgcagtgcta taagaacaga acgcattttg gatgttatta ttaagaacca   1380

aatgtcaata cagaattcat gttgccggtt tcccactttt ctttttacat taatgcatag   1440

ctgcttccat ttatgagact ttagagtttg agtttctgta gggctgaatg actctttttc   1500

ctgcccaggg cccattcttg cttctcaggc accttccgtt tattaattgc cattgctcct   1560

gacatcacta agatgggtcc ccttctggct gcatgaatgg aaatgagtga ctggaaatcc   1620

cataggccac aagaatgact ttcacaaggg caggaacatt gtggaaagac tgcatcattc   1680

tgatgaggca aaatcctcca gctattcctg tctgggccag ttttgtaggt ccatctgtgc   1740

atgggcagca gtagtcaaaa agccaaggaa aaaacagagc agacctgaag gctaatctta   1800

tttttgccac taacttagtg aatgacccta agcaagttcc ttctcctctt agggccttgt   1860

gccaagccta tgaaattgga ggtggctttc ctgctctaaa gcattttgat gtctcattct   1920

gtgtttggta acccctataa actggggcag aggaaaagaa tgatggttca aggccatact   1980

tcccttgaac cttgtgtggt tcttgcctaa ctctgtggtt tttggacccc atggggccca   2040

gacagagcac aggagcatgg gctgcctctg agtgtggtgt tgaacttcgg gaggagcagg   2100

gagccctgca ccttgtgtcc tggcccacct gacctttggt gttctccgga tccttttcag   2160

cccgaggcct gacagacgcg ggcagtgatg agccctgttc tggagtggaa agagcacgat   2220

agagcaccag gctaagaggc acgagatcaa ggcggtagtc acttccgctc tgcagctagc   2280

atttcaacca tatgtggatc ctttcatttc tcagctccct ggattccttc ccctaaatta   2340

ggacctatta tttacctgta ggtaagcaag ctactgtagc tcttctgagg tatctgccag   2400

gctgttttct gtagcctcag attgcctatc tgcttagcct gagaacaggt agatgaaaac   2460

taaactgatg cctaggccca gggtcagtct cagatggaag ctgggcctgg gtggggaggc   2520

tagcatgcgt ggctccctgg gtatttctgt cagtccccat ggcaagcagt gatttagtaa   2580

aacaccccag agtcagggaa gccaaccacc ttgaaacctt tagaacatct ctgctttgga   2640

gaaagaccca gagatcaggc agaggtgcag attcaatcat tactcataac ctttgagaga   2700

tggcaaatgg gaggagtgtt agtctttgtt ttggaattgg accattcttg caaccaaaag   2760

gacttagagc agtttgctca taaagacatc ctttattata aaaggaagta tttaaaggat   2820

gatagagacc atcagataga agcagggaag gtagataact tttaggacct tgatgtgagg   2880

aaaagataaa atttaaacaa taaatttgcc acttagattt tctagcagca aagtccgaaa   2940

agatagttat atacaaaatt ctgttttctg aaaacaaaat tgtgattcac cttcagaatt   3000

ggccattttt tttgtgagtt tccttgcatc aaggacactg agaaacacag tcattgtctt   3060

aggtgttcta tgggaggaag tgaatagagc ctttaggaac ttcctggtca agcttatggt   3120

gcttattttg atctgggcca cttccctcct tccagtcatg agtaatcatc aaggagcaag   3180

ttggagtgtt tcaggtgtat attttgtaga acccaaaaga ttggagcctt aacaataaac   3240

atcagcacta agtgacctgt tc                                            3262


<210>  9458
<211>  271
<212>  PRT
<213>  Homo sapiens

<400>  9458

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
            260                 265                 270


<210>  9459
<211>  198
<212>  DNA
<213>  Homo sapiens

<400>  9459
cgcgggcaca gcgtcctcca agaggccacc ttgctgagag gcagacttcc catccacaaa     60

atgggatgac aaaacggctc agagttgaaa ccacttctcc aaggagacac aactgctgcc    120

cgcagagctg aagctcctga cccactatca aatttcaatc atttatttgc ctaccccctt    180

tatgattttt accacccg                                                  198


<210>  9460
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  9460

Gln Asn Gly Ser Glu Leu Lys Pro Leu Leu Gln Gly Asp Thr Thr Ala 
1               5                   10                  15


Ala Arg Arg Ala Glu Ala Pro Asp Pro Leu Ser Asn Phe Asn His Leu 
            20                  25                  30


Phe Ala Tyr Pro Leu Tyr Asp Phe Tyr His 
        35                  40


<210>  9461
<211>  701
<212>  DNA
<213>  Homo sapiens

<400>  9461
gaggggccac gccccgctcg cactccctgg cggaaccttt cagtgctgcg ctcgcgttgc     60

caacccggcg cgcctcacgc agttgcgccc gctgttggga ctacttccgg cttccccgcc    120

ccgccccgtc cccgggcgtc tccattttgg tctcagacgc cgaagtcgcg ggcgctcatg    180

gcgggcctgg aggtactgtt cgcatcggca gcgccggcca tcacctgcag gcaggacgcg    240

ctcgtctgct tcttgcattg ggaagtggtg acacacggtt acttcggctt gggtgtcggt    300

gaccagccgg gtcccaatga taagaagtca gaactgctgc cagctgggtg gaacaacaat    360

aaagacctgt atgtcctccg gtatgagtat aaggatgggt ccagaaagct ccttgtgaaa    420

gccatcaccg tggagagcag catgatcctc aatgtgctgg aatatggctc acagcaagtg    480

gcagacttga ccctgaactt ggatgattat atcgatgcag aacacctggg tgacttccac    540

aggacctaca agaacagtga ggagcttcgg tctcgtattg tgtctggaat catcacacct    600

atccatgagc agtgggaaaa ggctaatgta agcagtcccc accgggagtt cccccctgct    660

accgccagag aggtggaccc actccggatt cctccacacc a                        701


<210>  9462
<211>  173
<212>  PRT
<213>  Homo sapiens

<400>  9462

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro 
                165                 170


<210>  9463
<211>  1396
<212>  DNA
<213>  Homo sapiens

<400>  9463
ctacttccgg cttccccgcc ccgccccgtc cccgggcgtc tccattttgg tctcaggtgt     60

ggactcggca agaaccagcg caagagggaa gcagagttat agctaccccg gccgcggagc    120

cggctcactg cactaccccc gcccccttct ttcctccaga cgccgaagtc gcgggcgctc    180

atggcgggcc tggaggtact gttcgcatcg gcagcgccgg ccatcacctg caggcaggac    240

gcgctcgtct gcttcttgca ttgggaagtg gtgacacacg gttacttcgg cttgggtgtc    300

ggtgaccagc cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac    360

aataaagacc tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg    420

aaagccatca ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa    480

gtggcagact tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc    540

cacaggacct acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca    600

cctatccatg agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct    660

gctaccgcca gagaggtgga cccactccgg attcctccac accacccaca caccagtcgg    720

cagcctccct ggtgtgatcc cctgggcccg tttgttgtcg ggggagaaga cttagaccct    780

tttgggcctc ggagaggtgg catgattgtg gatcccctga gatctggctt cccaagagca    840

cttattgacc cttcctcagg cctcccgaac cgacttcctc caggcgctgt gcccccagga    900

gctcgctttg acccctttgg acccattggg accagcccac ccggacctaa cccagaccat    960

ctccccccgc cgggctacga tgacatgtac ctgtgaaggc ctcaagaatg taacatccca   1020

ggcttccctc cattctcctg gagctgccac cgctgtcccc atcagcaacc atgttcttgc   1080

aggctggggg caagggattc tgctcatgtg tttgcagacc ggctgggata gcctccccac   1140

cccttatcag agccaagaca cctgctgcag ctctccacct agctgcagat agctcccaaa   1200

gagaaatcag tgtgtctctt tcaccatcag ctcctcccct ttcaccacca gctcctctcc   1260

acttcccaag ggagactccg gcaaccttca gcaacatata tcctcgacca gatgcagtgc   1320

tataagaaca gaacgcattt tggatgttat tattaagaac caaatgtcaa tacagaattc   1380

atgttgccgg tttccc                                                   1396


<210>  9464
<211>  271
<212>  PRT
<213>  Homo sapiens

<400>  9464

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
            260                 265                 270


<210>  9465
<211>  2046
<212>  DNA
<213>  Homo sapiens

<400>  9465
ctacttccgg cttccccgcc ccgccccgtc cccgggcgtc tccattttgg tctcaggtgt     60

ggactcggca agaaccagcg caagagggaa gcagagttat agctaccccg gccgcggagc    120

cggctcactg cactaccccc gcccccttct ttcctccaga cgccgaagtc gcgggcgctc    180

atggcgggcc tggaggtact gttcgcatcg gcagcgccgg ccatcacctg caggcaggac    240

gcgctcgtct gcttcttgca ttgggaagtg gtgacacacg gttacttcgg cttgggtgtc    300

ggtgaccagc cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac    360

aataaagacc tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg    420

aaagccatca ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa    480

gtggcagact tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc    540

cacaggacct acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca    600

cctatccatg agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct    660

gctaccgcca gagaggtgga cccactccgg attcctccac accacccaca caccagtcgg    720

cagcctccct ggtgtgatcc cctgggcccg tttgttgtcg ggggagaaga cttagaccct    780

tttgggcctc ggagaggtgg catgattgtg gatcccctga gatctggctt cccaagagca    840

cttattgacc cttcctcagg cctcccgaac cgacttcctc caggcgctgt gcccccagga    900

gctcgctttg acccctttgg acccattggg accagcccac ccggcccgag gcctgacaga    960

cgcgggcagt gatgagccct gttctggagt ggaaagagca cgatagagca ccaggctaag   1020

aggcacgaga tcaaggcggt agtcacttcc gctctgcagc tagcatttca accatatgtg   1080

gatcctttca tttctcagct ccctggattc cttcccctaa attaggacct attatttacc   1140

tgtaggtaag caagctactg tagctcttct gaggtatctg ccaggctgtt ttctgtagcc   1200

tcagattgcc tatctgctta gcctgagaac aggtagatga aaactaaact gatgcctagg   1260

cccagggtca gtctcagatg gaagctgggc ctgggtgggg aggctagcat gcgtggctcc   1320

ctgggtattt ctgtcagtcc ccatggcaag cagtgattta gtaaaacacc ccagagtcag   1380

ggaagccaac caccttgaaa cctttagaac atctctgctt tggagaaaga cccagagatc   1440

aggcagaggt gcagattcaa tcattactca taacctttga gagatggcaa atgggaggag   1500

tgttagtctt tgttttggaa ttggaccatt cttgcaacca aaaggactta gagcagtttg   1560

ctcataaaga catcctttat tataaaagga agtatttaaa ggatgataga gaccatcaga   1620

tagaagcagg gaaggtagat aacttttagg accttgatgt gaggaaaaga taaaatttaa   1680

acaataaatt tgccacttag attttctagc agcaaagtcc gaaaagatag ttatatacaa   1740

aattctgttt tctgaaaaca aaattgtgat tcaccttcag aattggccat tttttttgtg   1800

agtttccttg catcaaggac actgagaaac acagtcattg tcttaggtgt tctatgggag   1860

gaagtgaata gagcctttag gaacttcctg gtcaagctta tggtgcttat tttgatctgg   1920

gccacttccc tccttccagt catgagtaat catcaaggag caagttggag tgtttcaggt   1980

gtatattttg tagaacccaa aagattggag ccttaacaat aaacatcagc actaagtgac   2040

ctgttc                                                              2046


<210>  9466
<211>  263
<212>  PRT
<213>  Homo sapiens

<400>  9466

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Arg Pro Asp Arg Arg Gly Gln 
            260


<210>  9467
<211>  3244
<212>  DNA
<213>  Homo sapiens

<400>  9467
ctacttccgg cttccccgcc ccgccccgtc cccgggcgtc tccattttgg tctcaggtgt     60

ggactcggca agaaccagcg caagagggaa gcagagttat agctaccccg gccgcggagc    120

cggctcactg cactaccccc gcccccttct ttcctccaga cgccgaagtc gcgggcgctc    180

atggcgggcc tggaggtact gttcgcatcg gcagcgccgg ccatcacctg caggcaggac    240

gcgctcgtct gcttcttgca ttgggaagtg gtgacacacg gttacttcgg cttgggtgtc    300

ggtgaccagc cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac    360

aataaagacc tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg    420

aaagccatca ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa    480

gtggcagact tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc    540

cacaggacct acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca    600

cctatccatg agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct    660

gctaccgcca gagaggtgga cccactccgg attcctccac accacccaca caccagtcgg    720

cagcctccct ggtgtgatcc cctgggcccg tttgttgtcg ggggagaaga cttagaccct    780

tttgggcctc ggagaggtgg catgattgtg gatcccctga gatctggctt cccaagagca    840

cttattgacc cttcctcagg cctcccgaac cgacttcctc caggcgctgt gcccccagga    900

gctcgctttg acccctttgg acccattggg accagcccac ccggacctaa cccagaccat    960

ctccccccgc cgggctacga tgacatgtac ctgtgaaggc ctcaagaatg taacatccca   1020

ggcttccctc cattctcctg gagctgccac cgctgtcccc atcagcaacc atgttcttgc   1080

aggctggggg caagggattc tgctcatgtg tttgcagacc ggctgggata gcctccccac   1140

cccttatcag agccaagaca cctgctgcag ctctccacct agctgcagat agctcccaaa   1200

gagaaatcag tgtgtctctt tcaccatcag ctcctcccct ttcaccacca gctcctctcc   1260

acttcccaag ggagactccg gcaaccttca gcaacatata tcctcgacca gatgcagtgc   1320

tataagaaca gaacgcattt tggatgttat tattaagaac caaatgtcaa tacagaattc   1380

atgttgccgg tttcccactt ttctttttac attaatgcat agctgcttcc atttatgaga   1440

ctttagagtt tgagtttctg tagggctgaa tgactctttt tcctgcccag ggcccattct   1500

tgcttctcag gcaccttccg tttattaatt gccattgctc ctgacatcac taagatgggt   1560

ccccttctgg ctgcatgaat ggaaatgagt gactggaaat cccataggcc acaagaatga   1620

ctttcacaag ggcaggaaca ttgtggaaag actgcatcat tctgatgagg caaaatcctc   1680

cagctattcc tgtctgggcc agttttgtag gtccatctgt gcatgggcag cagtagtcaa   1740

aaagccaagg aaaaaacaga gcagacctga aggctaatct tatttttgcc actaacttag   1800

tgaatgaccc taagcaagtt ccttctcctc ttagggcctt gtgccaagcc tatgaaattg   1860

gaggtggctt tcctgctcta aagcattttg atgtctcatt ctgtgtttgg taacccctat   1920

aaactggggc agaggaaaag aatgatggtt caaggccata cttcccttga accttgtgtg   1980

gttcttgcct aactctgtgg tttttggacc ccatggggcc cagacagagc acaggagcat   2040

gggctgcctc tgagtgtggt gttgaacttc gggaggagca gggagccctg caccttgtgt   2100

cctggcccac ctgacctttg gtgttctccg gatccttttc agcccgaggc ctgacagacg   2160

cgggcagtga tgagccctgt tctggagtgg aaagagcacg atagagcacc aggctaagag   2220

gcacgagatc aaggcggtag tcacttccgc tctgcagcta gcatttcaac catatgtgga   2280

tcctttcatt tctcagctcc ctggattcct tcccctaaat taggacctat tatttacctg   2340

taggtaagca agctactgta gctcttctga ggtatctgcc aggctgtttt ctgtagcctc   2400

agattgccta tctgcttagc ctgagaacag gtagatgaaa actaaactga tgcctaggcc   2460

cagggtcagt ctcagatgga agctgggcct gggtggggag gctagcatgc gtggctccct   2520

gggtatttct gtcagtcccc atggcaagca gtgatttagt aaaacacccc agagtcaggg   2580

aagccaacca ccttgaaacc tttagaacat ctctgctttg gagaaagacc cagagatcag   2640

gcagaggtgc agattcaatc attactcata acctttgaga gatggcaaat gggaggagtg   2700

ttagtctttg ttttggaatt ggaccattct tgcaaccaaa aggacttaga gcagtttgct   2760

cataaagaca tcctttatta taaaaggaag tatttaaagg atgatagaga ccatcagata   2820

gaagcaggga aggtagataa cttttaggac cttgatgtga ggaaaagata aaatttaaac   2880

aataaatttg ccacttagat tttctagcag caaagtccga aaagatagtt atatacaaaa   2940

ttctgttttc tgaaaacaaa attgtgattc accttcagaa ttggccattt tttttgtgag   3000

tttccttgca tcaaggacac tgagaaacac agtcattgtc ttaggtgttc tatgggagga   3060

agtgaataga gcctttagga acttcctggt caagcttatg gtgcttattt tgatctgggc   3120

cacttccctc cttccagtca tgagtaatca tcaaggagca agttggagtg tttcaggtgt   3180

atattttgta gaacccaaaa gattggagcc ttaacaataa acatcagcac taagtgacct   3240

gttc                                                                3244


<210>  9468
<211>  271
<212>  PRT
<213>  Homo sapiens

<400>  9468

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
            260                 265                 270


<210>  9469
<211>  4910
<212>  DNA
<213>  Homo sapiens

<400>  9469
ctacttccgg cttccccgcc ccgccccgtc cccgggcgtc tccattttgg tctcaggtgt     60

ggactcggca agaaccagcg caagagggaa gcagagttat agctaccccg gccgcggagc    120

cggctcactg cactaccccc gcccccttct ttcctccaga cgccgaagtc gcgggcgctc    180

atggcgggcc tggaggtact gttcgcatcg gcagcgccgg ccatcacctg caggcaggac    240

gcgctcgtct gcttcttgca ttgggaagtg gtgacacacg gttacttcgg cttgggtgtc    300

ggtgaccagc cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac    360

aataaagacc tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg    420

aaagccatca ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa    480

gtggcagact tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc    540

cacaggacct acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca    600

cctatccatg agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct    660

gctaccgcca gagaggtgga cccactccgg attcctccac accacccaca caccagtcgg    720

cagcctccct ggtgtgatcc cctgggcccg tttgttgtcg ggggagaaga cttagaccct    780

tttgggcctc ggagaggtgg catgattgtg gatcccctga gatctggctt cccaagagca    840

cttattgacc cttcctcagg cctcccgaac cgacttcctc caggcgctgt gcccccagga    900

gctcgctttg acccctttgg acccattggg accagcccac ccggacctaa cccagaccat    960

ctccccccgc cgggctacga tgacatgtac ctgtgaaggc ctcaagaatg taacatccca   1020

ggcttccctc cattctcctg gagctgccac cgctgtcccc atcagcaacc atgttcttgc   1080

aggctggggg caagggattc tgctcatgtg tttgcagacc ggctgggata gcctccccac   1140

cccttatcag agccaagaca cctgctgcag ctctccacct agctgcagat agctcccaaa   1200

gagaaatcag tgtgtctctt tcaccatcag ctcctcccct ttcaccacca gctcctctcc   1260

acttcccaag ggagactccg gcaaccttca gcaacatata tcctcgacca gatgcagtgc   1320

tataagaaca gaacgcattt tggatgttat tattaagaac caaatgtcaa tacagaattc   1380

atgttgccgg tttcccactt ttctttttac attaatgcat agctgcttcc atttatgaga   1440

ctttagagtt tgagtttctg tagggctgaa tgactctttt tcctgcccag ggcccattct   1500

tgcttctcag gcaccttccg tttattaatt gccattgctc ctgacatcac taagatgggt   1560

ccccttctgg ctgcatgaat ggaaatgagt gactggaaat cccataggcc acaagaatga   1620

ctttcacaag ggcaggaaca ttgtggaaag actgcatcat tctgatgagg caaaatcctc   1680

cagctattcc tgtctgggcc agttttgtag gtccatctgt gcatgggcag cagtagtcaa   1740

aaagccaagg aaaaaacaga gcagacctga aggctaatct tatttttgcc actaacttag   1800

tgaatgaccc taagcaagtt ccttctcctc ttagggcctt gtgccaagcc tatgaaattg   1860

gaggtggctt tcctgctcta aagcattttg atgtctcatt ctgtgtttgg taacccctat   1920

aaactggggc agaggaaaag aatgatggtt caaggccata cttcccttga accttgtgtg   1980

gttcttgcct aactctgtgg tttttggacc ccatggggcc cagacagagc acaggagcat   2040

gggctgcctc tgagtgtggt gttgaacttc gggaggagca gggagccctg caccttgtgt   2100

cctggcccac ctgacctttg gtgttctccg gatccttttc agcccgaggc ctgacagacg   2160

cgggcagtga tgagccctgt tctggagtgg aaagagcacg atagagcacc aggctaagag   2220

gcacgagatc aaggcggtag tcacttccgc tctgcagcta gcatttcaac catatgtgga   2280

tcctttcatt tctcagctcc ctggattcct tcccctaaat taggacctat tatttacctg   2340

taggtaagca agctactgta gctcttctga ggtatctgcc aggctgtttt ctgtagcctc   2400

agattgccta tctgcttagc ctgagaacag gtagatgaaa actaaactga tgcctaggcc   2460

cagggtcagt ctcagatgga agctgggcct gggtggggag gctagcatgc gtggctccct   2520

gggtatttct gtcagtcccc atggcaagca gtgatttagt aaaacacccc agagtcaggg   2580

aagccaacca ccttgaaacc tttagaacat ctctgctttg gagaaagacc cagagatcag   2640

gcagaggtgc agattcaatc attactcata acctttgaga gatggcaaat gggaggagtg   2700

ttagtctttg ttttggaatt ggaccattct tgcaaccaaa aggacttaga gcagtttgct   2760

cataaagaca tcctttatta taaaaggaag tatttaaagg atgatagaga ccatcagata   2820

gaagcaggga aggtagataa cttttaggac cttgatgtga ggaaaagata aaatttaaac   2880

aataaatttg ccacttagat tttctagcag caaagtccga aaagatagtt atatacaaaa   2940

ttctgttttc tgaaaacaaa attgtgattc accttcagaa ttggccattt tttttgtgag   3000

tttccttgca tcaaggacac tgagaaacac agtcattgtc ttaggtgttc tatgggagga   3060

agtgaataga gcctttagga acttcctggt caagcttatg gtgcttattt tgatctgggc   3120

cacttccctc cttccagtca tgagtaatca tcaaggagca agttggagtg tttcaggtgt   3180

atattttgta gaacccaaaa gattggagcc ttaacaataa acatcagcac taagtgacct   3240

gttcctcctt ttttaaatag cagctttatt gagatataat ttacataccc ataatttaca   3300

tacctgttta aagtatacaa ttcagtggat ttagtatgtt cacagtgttg cacatccacc   3360

accatttcta attcctgaac attttcacca cctcaaaaag aaaccacaca cccattggca   3420

tgactcccca ttcccttgct cccagcccca ggcaaccact aacatctgtc tctaaagatt   3480

tttttttttt ttctggacag ttctcataag tggaatcact cagtattatg gccttttgtg   3540

tctggcttct ttcatttcat gtgatgtttt caagattcat tcatgctgta gcatgtatcc   3600

atggtatgga tatatcacat tttgcttatc cttttatcag ttgatggaca gttgggttgt   3660

ttctacaaaa aggctattat gagtaatgca gccaagaaca tttgtgtacc agtttttgag   3720

ttttcagttg tttgagtttc agatgttttc agttcatttg ggtatatacc aaggagtgga   3780

attgctggtt cacatggtag ctctatattc tactttgtga ggaattgtca gactgttttc   3840

cacggaagct gcaccatttt acatttccac tggtaattta tgagggttcc agtttcccca   3900

catcttcacc aactcttgtt atttttcatg cttatggcca tcctagttag cgtgaagtag   3960

catctcattg tggtcttctc ttccattttt taaaaaagaa ttttgaccta caccaagcaa   4020

ggcagagacc agagtcagtc ccccttgggg agcaatctgt ggttttgata atcaccacct   4080

tgggatgaac atggctggtg agctgcagag cagttgattt gacttttggg gatggttcta   4140

ggctggatgt gatacagggc aggttttgtc tctagagaaa gttctcatga ccttcaggtc   4200

taatgagatt cagatcatca ctttggtttg gtttgaaatt tctttgttta tccagtgaat   4260

tacaagtaga ataaagatct ggttctaaat tgtcttttgg tggtgaagtg ccatagacca   4320

tttcggacca tttctatgat gtaccagcag cccccacatc acacctcctc ttccttggct   4380

tgtctcttcc ccaattctta gagttagcag tgtttcttac tgcattcatc tcctcagtca   4440

taagtgtctg tcaacctccg ttgtgaagtc atgagtctct tgagactgaa actccaagaa   4500

tgtattgtgc tcacagtggc gatggtgttc ctgtgctgga tggtcagtgg ttgttgacat   4560

gtagttagaa aataggtagc aagttccacg cagcctcact ctttggaacc tagtttctcc   4620

tatggcctcc ctttctactg ttgttaataa cattctatta atgatccatg cctctcttca   4680

caggaggaat attagaatct atggagcagt tagtattctt tgtcacctaa atttgtctac   4740

ttctgtacat ttccaataag gcaccaccag ggcaagggaa gattccccac atgtatatcc   4800

ccagctgttt ctgtcataaa acttgcatgt gtataaacca ctattgactt tttgcaccaa   4860

aggagatatt caaggacaga catccaagtc cccagccctt tattgccctt              4910


<210>  9470
<211>  271
<212>  PRT
<213>  Homo sapiens

<400>  9470

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
            260                 265                 270


<210>  9471
<211>  3712
<212>  DNA
<213>  Homo sapiens

<400>  9471
ctacttccgg cttccccgcc ccgccccgtc cccgggcgtc tccattttgg tctcaggtgt     60

ggactcggca agaaccagcg caagagggaa gcagagttat agctaccccg gccgcggagc    120

cggctcactg cactaccccc gcccccttct ttcctccaga cgccgaagtc gcgggcgctc    180

atggcgggcc tggaggtact gttcgcatcg gcagcgccgg ccatcacctg caggcaggac    240

gcgctcgtct gcttcttgca ttgggaagtg gtgacacacg gttacttcgg cttgggtgtc    300

ggtgaccagc cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac    360

aataaagacc tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg    420

aaagccatca ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa    480

gtggcagact tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc    540

cacaggacct acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca    600

cctatccatg agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct    660

gctaccgcca gagaggtgga cccactccgg attcctccac accacccaca caccagtcgg    720

cagcctccct ggtgtgatcc cctgggcccg tttgttgtcg ggggagaaga cttagaccct    780

tttgggcctc ggagaggtgg catgattgtg gatcccctga gatctggctt cccaagagca    840

cttattgacc cttcctcagg cctcccgaac cgacttcctc caggcgctgt gcccccagga    900

gctcgctttg acccctttgg acccattggg accagcccac ccggcccgag gcctgacaga    960

cgcgggcagt gatgagccct gttctggagt ggaaagagca cgatagagca ccaggctaag   1020

aggcacgaga tcaaggcggt agtcacttcc gctctgcagc tagcatttca accatatgtg   1080

gatcctttca tttctcagct ccctggattc cttcccctaa attaggacct attatttacc   1140

tgtaggtaag caagctactg tagctcttct gaggtatctg ccaggctgtt ttctgtagcc   1200

tcagattgcc tatctgctta gcctgagaac aggtagatga aaactaaact gatgcctagg   1260

cccagggtca gtctcagatg gaagctgggc ctgggtgggg aggctagcat gcgtggctcc   1320

ctgggtattt ctgtcagtcc ccatggcaag cagtgattta gtaaaacacc ccagagtcag   1380

ggaagccaac caccttgaaa cctttagaac atctctgctt tggagaaaga cccagagatc   1440

aggcagaggt gcagattcaa tcattactca taacctttga gagatggcaa atgggaggag   1500

tgttagtctt tgttttggaa ttggaccatt cttgcaacca aaaggactta gagcagtttg   1560

ctcataaaga catcctttat tataaaagga agtatttaaa ggatgataga gaccatcaga   1620

tagaagcagg gaaggtagat aacttttagg accttgatgt gaggaaaaga taaaatttaa   1680

acaataaatt tgccacttag attttctagc agcaaagtcc gaaaagatag ttatatacaa   1740

aattctgttt tctgaaaaca aaattgtgat tcaccttcag aattggccat tttttttgtg   1800

agtttccttg catcaaggac actgagaaac acagtcattg tcttaggtgt tctatgggag   1860

gaagtgaata gagcctttag gaacttcctg gtcaagctta tggtgcttat tttgatctgg   1920

gccacttccc tccttccagt catgagtaat catcaaggag caagttggag tgtttcaggt   1980

gtatattttg tagaacccaa aagattggag ccttaacaat aaacatcagc actaagtgac   2040

ctgttcctcc ttttttaaat agcagcttta ttgagatata atttacatac ccataattta   2100

catacctgtt taaagtatac aattcagtgg atttagtatg ttcacagtgt tgcacatcca   2160

ccaccatttc taattcctga acattttcac cacctcaaaa agaaaccaca cacccattgg   2220

catgactccc cattcccttg ctcccagccc caggcaacca ctaacatctg tctctaaaga   2280

tttttttttt ttttctggac agttctcata agtggaatca ctcagtatta tggccttttg   2340

tgtctggctt ctttcatttc atgtgatgtt ttcaagattc attcatgctg tagcatgtat   2400

ccatggtatg gatatatcac attttgctta tccttttatc agttgatgga cagttgggtt   2460

gtttctacaa aaaggctatt atgagtaatg cagccaagaa catttgtgta ccagtttttg   2520

agttttcagt tgtttgagtt tcagatgttt tcagttcatt tgggtatata ccaaggagtg   2580

gaattgctgg ttcacatggt agctctatat tctactttgt gaggaattgt cagactgttt   2640

tccacggaag ctgcaccatt ttacatttcc actggtaatt tatgagggtt ccagtttccc   2700

cacatcttca ccaactcttg ttatttttca tgcttatggc catcctagtt agcgtgaagt   2760

agcatctcat tgtggtcttc tcttccattt tttaaaaaag aattttgacc tacaccaagc   2820

aaggcagaga ccagagtcag tcccccttgg ggagcaatct gtggttttga taatcaccac   2880

cttgggatga acatggctgg tgagctgcag agcagttgat ttgacttttg gggatggttc   2940

taggctggat gtgatacagg gcaggttttg tctctagaga aagttctcat gaccttcagg   3000

tctaatgaga ttcagatcat cactttggtt tggtttgaaa tttctttgtt tatccagtga   3060

attacaagta gaataaagat ctggttctaa attgtctttt ggtggtgaag tgccatagac   3120

catttcggac catttctatg atgtaccagc agcccccaca tcacacctcc tcttccttgg   3180

cttgtctctt ccccaattct tagagttagc agtgtttctt actgcattca tctcctcagt   3240

cataagtgtc tgtcaacctc cgttgtgaag tcatgagtct cttgagactg aaactccaag   3300

aatgtattgt gctcacagtg gcgatggtgt tcctgtgctg gatggtcagt ggttgttgac   3360

atgtagttag aaaataggta gcaagttcca cgcagcctca ctctttggaa cctagtttct   3420

cctatggcct ccctttctac tgttgttaat aacattctat taatgatcca tgcctctctt   3480

cacaggagga atattagaat ctatggagca gttagtattc tttgtcacct aaatttgtct   3540

acttctgtac atttccaata aggcaccacc agggcaaggg aagattcccc acatgtatat   3600

ccccagctgt ttctgtcata aaacttgcat gtgtataaac cactattgac tttttgcacc   3660

aaaggagata ttcaaggaca gacatccaag tccccagccc tttattgccc tt           3712


<210>  9472
<211>  263
<212>  PRT
<213>  Homo sapiens

<400>  9472

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro 
                165                 170                 175


His Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val 
            180                 185                 190


Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met 
        195                 200                 205


Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro 
    210                 215                 220


Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly 
225                 230                 235                 240


Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro 
                245                 250                 255


Arg Pro Asp Arg Arg Gly Gln 
            260


<210>  9473
<211>  1932
<212>  DNA
<213>  Homo sapiens

<400>  9473
tacttccggc ttccccgccc cgccccgtcc ccgggcgtct ccattttggt ctcaggtgtg     60

gactcggcaa gaaccagcgc aagagggaag cagagttata gctaccccgg ccgcggagcc    120

ggctcactgc actacccccg cccccttctt tcctccagac gccgaagtcg cgggcgctca    180

tggcgggcct ggaggtactg ttcgcatcgg cagcgccggc catcacctgc aggcaggacg    240

cgctcgtctg cttcttgcat tgggaagtgg tgacacacgg ttacttcggc ttgggtgtcg    300

gtgaccagcc gggtcccaat gataagaagt cagaactgct gccagctggg tggaacaaca    360

ataaagacct gtatgtcctc cggtatgagt ataaggatgg gtccagaaag ctccttgtga    420

aagccatcac cgtggagagc agcatgatcc tcaatgtgct ggaatatggc tcacagcaag    480

tggcagactt gaccctgaac ttggatgatt atatcgatgc agaacacctg ggtgacttcc    540

acaggaccta caagaacagt gaggagcttc ggtctcgtat tgtgtctgga atcatcacac    600

ctatccatga gcagtgggaa aaggctaatg taagcagtcc ccaccgggag ttcccccctg    660

ctaccgccag agcctcggag aggtggcatg attgtggatc ccctgagatc tggcttccca    720

agagcactta ttgacccttc ctcaggcctc ccgaaccgac ttcctccagg cgctgtgccc    780

ccaggagctc gctttgaccc ctttggaccc attgggacca gcccacccgg cccgaggcct    840

gacagacgcg ggcagtgatg agccctgttc tggagtggaa agagcacgat agagcaccag    900

gctaagaggc acgagatcaa ggcggtagtc acttccgctc tgcagctagc atttcaacca    960

tatgtggatc ctttcatttc tcagctccct ggattccttc ccctaaatta ggacctatta   1020

tttacctgta ggtaagcaag ctactgtagc tcttctgagg tatctgccag gctgttttct   1080

gtagcctcag attgcctatc tgcttagcct gagaacaggt agatgaaaac taaactgatg   1140

cctaggccca gggtcagtct cagatggaag ctgggcctgg gtggggaggc tagcatgcgt   1200

ggctccctgg gtatttctgt cagtccccat ggcaagcagt gatttagtaa aacaccccag   1260

agtcagggaa gccaaccacc ttgaaacctt tagaacatct ctgctttgga gaaagaccca   1320

gagatcaggc agaggtgcag attcaatcat tactcataac ctttgagaga tggcaaatgg   1380

gaggagtgtt agtctttgtt ttggaattgg accattcttg caaccaaaag gacttagagc   1440

agtttgctca taaagacatc ctttattata aaaggaagta tttaaaggat gatagagacc   1500

atcagataga agcagggaag gtagataact tttaggacct tgatgtgagg aaaagataaa   1560

atttaaacaa taaatttgcc acttagattt tctagcagca aagtccgaaa agatagttat   1620

atacaaaatt ctgttttctg aaaacaaaat tgtgattcac cttcagaatt ggccattttt   1680

tttgtgagtt tccttgcatc aaggacactg agaaacacag tcattgtctt aggtgttcta   1740

tgggaggaag tgaatagagc ctttaggaac ttcctggtca agcttatggt gcttattttg   1800

atctgggcca cttccctcct tccagtcatg agtaatcatc aaggagcaag ttggagtgtt   1860

tcaggtgtat attttgtaga acccaaaaga ttggagcctt aacaataaac atcagcacta   1920

agtgacctgt tc                                                       1932


<210>  9474
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  9474

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Ala Ser Glu Arg Trp His Asp Cys Gly Ser Pro Glu 
                165                 170                 175


Ile Trp Leu Pro Lys Ser Thr Tyr 
            180


<210>  9475
<211>  3598
<212>  DNA
<213>  Homo sapiens

<400>  9475
tacttccggc ttccccgccc cgccccgtcc ccgggcgtct ccattttggt ctcaggtgtg     60

gactcggcaa gaaccagcgc aagagggaag cagagttata gctaccccgg ccgcggagcc    120

ggctcactgc actacccccg cccccttctt tcctccagac gccgaagtcg cgggcgctca    180

tggcgggcct ggaggtactg ttcgcatcgg cagcgccggc catcacctgc aggcaggacg    240

cgctcgtctg cttcttgcat tgggaagtgg tgacacacgg ttacttcggc ttgggtgtcg    300

gtgaccagcc gggtcccaat gataagaagt cagaactgct gccagctggg tggaacaaca    360

ataaagacct gtatgtcctc cggtatgagt ataaggatgg gtccagaaag ctccttgtga    420

aagccatcac cgtggagagc agcatgatcc tcaatgtgct ggaatatggc tcacagcaag    480

tggcagactt gaccctgaac ttggatgatt atatcgatgc agaacacctg ggtgacttcc    540

acaggaccta caagaacagt gaggagcttc ggtctcgtat tgtgtctgga atcatcacac    600

ctatccatga gcagtgggaa aaggctaatg taagcagtcc ccaccgggag ttcccccctg    660

ctaccgccag agcctcggag aggtggcatg attgtggatc ccctgagatc tggcttccca    720

agagcactta ttgacccttc ctcaggcctc ccgaaccgac ttcctccagg cgctgtgccc    780

ccaggagctc gctttgaccc ctttggaccc attgggacca gcccacccgg cccgaggcct    840

gacagacgcg ggcagtgatg agccctgttc tggagtggaa agagcacgat agagcaccag    900

gctaagaggc acgagatcaa ggcggtagtc acttccgctc tgcagctagc atttcaacca    960

tatgtggatc ctttcatttc tcagctccct ggattccttc ccctaaatta ggacctatta   1020

tttacctgta ggtaagcaag ctactgtagc tcttctgagg tatctgccag gctgttttct   1080

gtagcctcag attgcctatc tgcttagcct gagaacaggt agatgaaaac taaactgatg   1140

cctaggccca gggtcagtct cagatggaag ctgggcctgg gtggggaggc tagcatgcgt   1200

ggctccctgg gtatttctgt cagtccccat ggcaagcagt gatttagtaa aacaccccag   1260

agtcagggaa gccaaccacc ttgaaacctt tagaacatct ctgctttgga gaaagaccca   1320

gagatcaggc agaggtgcag attcaatcat tactcataac ctttgagaga tggcaaatgg   1380

gaggagtgtt agtctttgtt ttggaattgg accattcttg caaccaaaag gacttagagc   1440

agtttgctca taaagacatc ctttattata aaaggaagta tttaaaggat gatagagacc   1500

atcagataga agcagggaag gtagataact tttaggacct tgatgtgagg aaaagataaa   1560

atttaaacaa taaatttgcc acttagattt tctagcagca aagtccgaaa agatagttat   1620

atacaaaatt ctgttttctg aaaacaaaat tgtgattcac cttcagaatt ggccattttt   1680

tttgtgagtt tccttgcatc aaggacactg agaaacacag tcattgtctt aggtgttcta   1740

tgggaggaag tgaatagagc ctttaggaac ttcctggtca agcttatggt gcttattttg   1800

atctgggcca cttccctcct tccagtcatg agtaatcatc aaggagcaag ttggagtgtt   1860

tcaggtgtat attttgtaga acccaaaaga ttggagcctt aacaataaac atcagcacta   1920

agtgacctgt tcctcctttt ttaaatagca gctttattga gatataattt acatacccat   1980

aatttacata cctgtttaaa gtatacaatt cagtggattt agtatgttca cagtgttgca   2040

catccaccac catttctaat tcctgaacat tttcaccacc tcaaaaagaa accacacacc   2100

cattggcatg actccccatt cccttgctcc cagccccagg caaccactaa catctgtctc   2160

taaagatttt tttttttttt ctggacagtt ctcataagtg gaatcactca gtattatggc   2220

cttttgtgtc tggcttcttt catttcatgt gatgttttca agattcattc atgctgtagc   2280

atgtatccat ggtatggata tatcacattt tgcttatcct tttatcagtt gatggacagt   2340

tgggttgttt ctacaaaaag gctattatga gtaatgcagc caagaacatt tgtgtaccag   2400

tttttgagtt ttcagttgtt tgagtttcag atgttttcag ttcatttggg tatataccaa   2460

ggagtggaat tgctggttca catggtagct ctatattcta ctttgtgagg aattgtcaga   2520

ctgttttcca cggaagctgc accattttac atttccactg gtaatttatg agggttccag   2580

tttccccaca tcttcaccaa ctcttgttat ttttcatgct tatggccatc ctagttagcg   2640

tgaagtagca tctcattgtg gtcttctctt ccatttttta aaaaagaatt ttgacctaca   2700

ccaagcaagg cagagaccag agtcagtccc ccttggggag caatctgtgg ttttgataat   2760

caccaccttg ggatgaacat ggctggtgag ctgcagagca gttgatttga cttttgggga   2820

tggttctagg ctggatgtga tacagggcag gttttgtctc tagagaaagt tctcatgacc   2880

ttcaggtcta atgagattca gatcatcact ttggtttggt ttgaaatttc tttgtttatc   2940

cagtgaatta caagtagaat aaagatctgg ttctaaattg tcttttggtg gtgaagtgcc   3000

atagaccatt tcggaccatt tctatgatgt accagcagcc cccacatcac acctcctctt   3060

ccttggcttg tctcttcccc aattcttaga gttagcagtg tttcttactg cattcatctc   3120

ctcagtcata agtgtctgtc aacctccgtt gtgaagtcat gagtctcttg agactgaaac   3180

tccaagaatg tattgtgctc acagtggcga tggtgttcct gtgctggatg gtcagtggtt   3240

gttgacatgt agttagaaaa taggtagcaa gttccacgca gcctcactct ttggaaccta   3300

gtttctccta tggcctccct ttctactgtt gttaataaca ttctattaat gatccatgcc   3360

tctcttcaca ggaggaatat tagaatctat ggagcagtta gtattctttg tcacctaaat   3420

ttgtctactt ctgtacattt ccaataaggc accaccaggg caagggaaga ttccccacat   3480

gtatatcccc agctgtttct gtcataaaac ttgcatgtgt ataaaccact attgactttt   3540

tgcaccaaag gagatattca aggacagaca tccaagtccc cagcccttta ttgccctt     3598


<210>  9476
<211>  184
<212>  PRT
<213>  Homo sapiens

<400>  9476

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Glu Tyr 
                85                  90                  95


Gly Ser Gln Gln Val Ala Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile 
            100                 105                 110


Asp Ala Glu His Leu Gly Asp Phe His Arg Thr Tyr Lys Asn Ser Glu 
        115                 120                 125


Glu Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu 
    130                 135                 140


Gln Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro 
145                 150                 155                 160


Ala Thr Ala Arg Ala Ser Glu Arg Trp His Asp Cys Gly Ser Pro Glu 
                165                 170                 175


Ile Trp Leu Pro Lys Ser Thr Tyr 
            180


<210>  9477
<211>  613
<212>  DNA
<213>  Homo sapiens

<400>  9477
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggaggta ctgttcgcat cggcagcgcc ggccatcacc tgcaggcagg acgcgctcgt    240

ctgcttcttg cattgggaag tggtgacaca cggttacttc ggcttgggtg tcggtgacca    300

gccgggtccc aatgataaga agtcagaact gctgccagct gggtggaaca acaataaaga    360

cctgtatgtc ctccggtatg agtataagga tgggtccaga aagctccttg tgaaagccat    420

caccgtggag agcagcatga tcctcaatgt gctggaccta caagaacagt gaggagcttc    480

ggtctcgtat tgtgtctgga atcatcacac ctatccatga gcagtgggaa aaggctaatg    540

taagcagtcc ccaccgggag ttcccccctg ctaccgccag agaggtggac ccactccgga    600

ttcctccaca cca                                                       613


<210>  9478
<211>  99
<212>  PRT
<213>  Homo sapiens

<400>  9478

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Pro Gly Pro Asn Asp 
        35                  40                  45


Lys Lys Ser Glu Leu Leu Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu 
    50                  55                  60


Tyr Val Leu Arg Tyr Glu Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val 
65                  70                  75                  80


Lys Ala Ile Thr Val Glu Ser Ser Met Ile Leu Asn Val Leu Asp Leu 
                85                  90                  95


Gln Glu Gln 



<210>  9479
<211>  521
<212>  DNA
<213>  Homo sapiens

<400>  9479
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggaggta ctgttcgcat cggcagcgcc ggccatcacc tgcaggcagg acgcgctcgt    240

ctgcttcttg cattgggaag tggtgacaca cggttacttc ggcttgggtg tcggtgacca    300

gtccacctag ctgcagatag ctcccaaaga gaaatcagtg tgtctctttc accatcagct    360

cctccccttt caccaccagc tcctctccac ttcccaaggg agactccggc aaccttcagc    420

aacatatatc ctcgaccaga tgcagtgcta taagaacaga acgcattttg gatgttatta    480

ttaagaacca aatgtcaata cagaattcat gttgccggtt t                        521


<210>  9480
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  9480

Met Ala Gly Leu Glu Val Leu Phe Ala Ser Ala Ala Pro Ala Ile Thr 
1               5                   10                  15


Cys Arg Gln Asp Ala Leu Val Cys Phe Leu His Trp Glu Val Val Thr 
            20                  25                  30


His Gly Tyr Phe Gly Leu Gly Val Gly Asp Gln Ser Thr 
        35                  40                  45


<210>  9481
<211>  1274
<212>  DNA
<213>  Homo sapiens

<400>  9481
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggagccg ggtcccaatg ataagaagtc agaactgctg ccagctgggt ggaacaacaa    240

taaagacctg tatgtcctcc ggtatgagta taaggatggg tccagaaagc tccttgtgaa    300

agccatcacc gtggagagca gcatgatcct caatgtgctg gaatatggct cacagcaagt    360

ggcagacttg accctgaact tggatgatta tatcgatgca gaacacctgg gtgacttcca    420

caggacctac aagaacagtg aggagcttcg gtctcgtatt gtgtctggaa tcatcacacc    480

tatccatgag cagtgggaaa aggctaatgt aagcagtccc caccgggagt tcccccctgc    540

taccgccaga gaggtggacc cactccggat tcctccacac cacccacaca ccagtcggca    600

gcctccctgg tgtgatcccc tgggcccgtt tgttgtcggg ggagaagact tagacccttt    660

tgggcctcgg agaggtggca tgattgtgga tcccctgaga tctggcttcc caagagcact    720

tattgaccct tcctcaggcc tcccgaaccg acttcctcca ggcgctgtgc ccccaggagc    780

tcgctttgac ccctttggac ccattgggac cagcccaccc ggacctaacc cagaccatct    840

ccccccgccg ggctacgatg acatgtacct gtgaaggcct caagaatgta acatcccagg    900

cttccctcca ttctcctgga gctgccaccg ctgtccccat cagcaaccat gttcttgcag    960

gctgggggca agggattctg ctcatgtgtt tgcagaccgg ctgggatagc ctccccaccc   1020

cttatcagag ccaagacacc tgctgcagct ctccacctag ctgcagatag ctcccaaaga   1080

gaaatcagtg tgtctctttc accatcagct cctccccttt caccaccagc tcctctccac   1140

ttcccaaggg agactccggc aaccttcagc aacatatatc ctcgaccaga tgcagtgcta   1200

taagaacaga acgcattttg gatgttatta ttaagaacca aatgtcaata cagaattcat   1260

gttgccggtt tccc                                                     1274


<210>  9482
<211>  233
<212>  PRT
<213>  Homo sapiens

<400>  9482

Met Ala Gly Leu Glu Pro Gly Pro Asn Asp Lys Lys Ser Glu Leu Leu 
1               5                   10                  15


Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu Tyr Val Leu Arg Tyr Glu 
            20                  25                  30


Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val Lys Ala Ile Thr Val Glu 
        35                  40                  45


Ser Ser Met Ile Leu Asn Val Leu Glu Tyr Gly Ser Gln Gln Val Ala 
    50                  55                  60


Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile Asp Ala Glu His Leu Gly 
65                  70                  75                  80


Asp Phe His Arg Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile 
                85                  90                  95


Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn 
            100                 105                 110


Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val 
        115                 120                 125


Asp Pro Leu Arg Ile Pro Pro His His Pro His Thr Ser Arg Gln Pro 
    130                 135                 140


Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val Gly Gly Glu Asp Leu 
145                 150                 155                 160


Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile Val Asp Pro Leu Arg 
                165                 170                 175


Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn 
            180                 185                 190


Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala Arg Phe Asp Pro Phe 
        195                 200                 205


Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn Pro Asp His Leu Pro 
    210                 215                 220


Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
225                 230


<210>  9483
<211>  3122
<212>  DNA
<213>  Homo sapiens

<400>  9483
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggagccg ggtcccaatg ataagaagtc agaactgctg ccagctgggt ggaacaacaa    240

taaagacctg tatgtcctcc ggtatgagta taaggatggg tccagaaagc tccttgtgaa    300

agccatcacc gtggagagca gcatgatcct caatgtgctg gaatatggct cacagcaagt    360

ggcagacttg accctgaact tggatgatta tatcgatgca gaacacctgg gtgacttcca    420

caggacctac aagaacagtg aggagcttcg gtctcgtatt gtgtctggaa tcatcacacc    480

tatccatgag cagtgggaaa aggctaatgt aagcagtccc caccgggagt tcccccctgc    540

taccgccaga gaggtggacc cactccggat tcctccacac cacccacaca ccagtcggca    600

gcctccctgg tgtgatcccc tgggcccgtt tgttgtcggg ggagaagact tagacccttt    660

tgggcctcgg agaggtggca tgattgtgga tcccctgaga tctggcttcc caagagcact    720

tattgaccct tcctcaggcc tcccgaaccg acttcctcca ggcgctgtgc ccccaggagc    780

tcgctttgac ccctttggac ccattgggac cagcccaccc ggacctaacc cagaccatct    840

ccccccgccg ggctacgatg acatgtacct gtgaaggcct caagaatgta acatcccagg    900

cttccctcca ttctcctgga gctgccaccg ctgtccccat cagcaaccat gttcttgcag    960

gctgggggca agggattctg ctcatgtgtt tgcagaccgg ctgggatagc ctccccaccc   1020

cttatcagag ccaagacacc tgctgcagct ctccacctag ctgcagatag ctcccaaaga   1080

gaaatcagtg tgtctctttc accatcagct cctccccttt caccaccagc tcctctccac   1140

ttcccaaggg agactccggc aaccttcagc aacatatatc ctcgaccaga tgcagtgcta   1200

taagaacaga acgcattttg gatgttatta ttaagaacca aatgtcaata cagaattcat   1260

gttgccggtt tcccactttt ctttttacat taatgcatag ctgcttccat ttatgagact   1320

ttagagtttg agtttctgta gggctgaatg actctttttc ctgcccaggg cccattcttg   1380

cttctcaggc accttccgtt tattaattgc cattgctcct gacatcacta agatgggtcc   1440

ccttctggct gcatgaatgg aaatgagtga ctggaaatcc cataggccac aagaatgact   1500

ttcacaaggg caggaacatt gtggaaagac tgcatcattc tgatgaggca aaatcctcca   1560

gctattcctg tctgggccag ttttgtaggt ccatctgtgc atgggcagca gtagtcaaaa   1620

agccaaggaa aaaacagagc agacctgaag gctaatctta tttttgccac taacttagtg   1680

aatgacccta agcaagttcc ttctcctctt agggccttgt gccaagccta tgaaattgga   1740

ggtggctttc ctgctctaaa gcattttgat gtctcattct gtgtttggta acccctataa   1800

actggggcag aggaaaagaa tgatggttca aggccatact tcccttgaac cttgtgtggt   1860

tcttgcctaa ctctgtggtt tttggacccc atggggccca gacagagcac aggagcatgg   1920

gctgcctctg agtgtggtgt tgaacttcgg gaggagcagg gagccctgca ccttgtgtcc   1980

tggcccacct gacctttggt gttctccgga tccttttcag cccgaggcct gacagacgcg   2040

ggcagtgatg agccctgttc tggagtggaa agagcacgat agagcaccag gctaagaggc   2100

acgagatcaa ggcggtagtc acttccgctc tgcagctagc atttcaacca tatgtggatc   2160

ctttcatttc tcagctccct ggattccttc ccctaaatta ggacctatta tttacctgta   2220

ggtaagcaag ctactgtagc tcttctgagg tatctgccag gctgttttct gtagcctcag   2280

attgcctatc tgcttagcct gagaacaggt agatgaaaac taaactgatg cctaggccca   2340

gggtcagtct cagatggaag ctgggcctgg gtggggaggc tagcatgcgt ggctccctgg   2400

gtatttctgt cagtccccat ggcaagcagt gatttagtaa aacaccccag agtcagggaa   2460

gccaaccacc ttgaaacctt tagaacatct ctgctttgga gaaagaccca gagatcaggc   2520

agaggtgcag attcaatcat tactcataac ctttgagaga tggcaaatgg gaggagtgtt   2580

agtctttgtt ttggaattgg accattcttg caaccaaaag gacttagagc agtttgctca   2640

taaagacatc ctttattata aaaggaagta tttaaaggat gatagagacc atcagataga   2700

agcagggaag gtagataact tttaggacct tgatgtgagg aaaagataaa atttaaacaa   2760

taaatttgcc acttagattt tctagcagca aagtccgaaa agatagttat atacaaaatt   2820

ctgttttctg aaaacaaaat tgtgattcac cttcagaatt ggccattttt tttgtgagtt   2880

tccttgcatc aaggacactg agaaacacag tcattgtctt aggtgttcta tgggaggaag   2940

tgaatagagc ctttaggaac ttcctggtca agcttatggt gcttattttg atctgggcca   3000

cttccctcct tccagtcatg agtaatcatc aaggagcaag ttggagtgtt tcaggtgtat   3060

attttgtaga acccaaaaga ttggagcctt aacaataaac atcagcacta agtgacctgt   3120

tc                                                                  3122


<210>  9484
<211>  233
<212>  PRT
<213>  Homo sapiens

<400>  9484

Met Ala Gly Leu Glu Pro Gly Pro Asn Asp Lys Lys Ser Glu Leu Leu 
1               5                   10                  15


Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu Tyr Val Leu Arg Tyr Glu 
            20                  25                  30


Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val Lys Ala Ile Thr Val Glu 
        35                  40                  45


Ser Ser Met Ile Leu Asn Val Leu Glu Tyr Gly Ser Gln Gln Val Ala 
    50                  55                  60


Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile Asp Ala Glu His Leu Gly 
65                  70                  75                  80


Asp Phe His Arg Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile 
                85                  90                  95


Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn 
            100                 105                 110


Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val 
        115                 120                 125


Asp Pro Leu Arg Ile Pro Pro His His Pro His Thr Ser Arg Gln Pro 
    130                 135                 140


Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val Gly Gly Glu Asp Leu 
145                 150                 155                 160


Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile Val Asp Pro Leu Arg 
                165                 170                 175


Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn 
            180                 185                 190


Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala Arg Phe Asp Pro Phe 
        195                 200                 205


Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn Pro Asp His Leu Pro 
    210                 215                 220


Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
225                 230


<210>  9485
<211>  3153
<212>  DNA
<213>  Homo sapiens

<400>  9485
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggaggta ctgttcgcat cggcagcgcc ggccatcacc tgcaggcagg acgcgctcgt    240

ctgcttcttg cattgggaag tggtgacaca cggttacttc ggcttgggtg tcggtgacca    300

gccgggtccc aatgataaga agtcagaact gctgccagct gggtggaaca acaataaaga    360

cctgtatgtc ctccggtatg agtataagga tgggtccaga aagctccttg tgaaagccat    420

caccgtggag agcagcatga tcctcaatgt gctggaccta caagaacagt gaggagcttc    480

ggtctcgtat tgtgtctgga atcatcacac ctatccatga gcagtgggaa aaggctaatg    540

taagcagtcc ccaccgggag ttcccccctg ctaccgccag agaggtggac ccactccgga    600

ttcctccaca ccacccacac accagtcggc agcctccctg gtgtgatccc ctgggcccgt    660

ttgttgtcgg gggagaagac ttagaccctt ttgggcctcg gagaggtggc atgattgtgg    720

atcccctgag atctggcttc ccaagagcac ttattgaccc ttcctcaggc ctcccgaacc    780

gacttcctcc aggcgctgtg cccccaggag ctcgctttga cccctttgga cccattggga    840

ccagcccacc cggacctaac ccagaccatc tccccccgcc gggctacgat gacatgtacc    900

tgtgaaggcc tcaagaatgt aacatcccag gcttccctcc attctcctgg agctgccacc    960

gctgtcccca tcagcaacca tgttcttgca ggctgggggc aagggattct gctcatgtgt   1020

ttgcagaccg gctgggatag cctccccacc ccttatcaga gccaagacac ctgctgcagc   1080

tctccaccta gctgcagata gctcccaaag agaaatcagt gtgtctcttt caccatcagc   1140

tcctcccctt tcaccaccag ctcctctcca cttcccaagg gagactccgg caaccttcag   1200

caacatatat cctcgaccag atgcagtgct ataagaacag aacgcatttt ggatgttatt   1260

attaagaacc aaatgtcaat acagaattca tgttgccggt ttcccacttt tctttttaca   1320

ttaatgcata gctgcttcca tttatgagac tttagagttt gagtttctgt agggctgaat   1380

gactcttttt cctgcccagg gcccattctt gcttctcagg caccttccgt ttattaattg   1440

ccattgctcc tgacatcact aagatgggtc cccttctggc tgcatgaatg gaaatgagtg   1500

actggaaatc ccataggcca caagaatgac tttcacaagg gcaggaacat tgtggaaaga   1560

ctgcatcatt ctgatgaggc aaaatcctcc agctattcct gtctgggcca gttttgtagg   1620

tccatctgtg catgggcagc agtagtcaaa aagccaagga aaaaacagag cagacctgaa   1680

ggctaatctt atttttgcca ctaacttagt gaatgaccct aagcaagttc cttctcctct   1740

tagggccttg tgccaagcct atgaaattgg aggtggcttt cctgctctaa agcattttga   1800

tgtctcattc tgtgtttggt aacccctata aactggggca gaggaaaaga atgatggttc   1860

aaggccatac ttcccttgaa ccttgtgtgg ttcttgccta actctgtggt ttttggaccc   1920

catggggccc agacagagca caggagcatg ggctgcctct gagtgtggtg ttgaacttcg   1980

ggaggagcag ggagccctgc accttgtgtc ctggcccacc tgacctttgg tgttctccgg   2040

atccttttca gcccgaggcc tgacagacgc gggcagtgat gagccctgtt ctggagtgga   2100

aagagcacga tagagcacca ggctaagagg cacgagatca aggcggtagt cacttccgct   2160

ctgcagctag catttcaacc atatgtggat cctttcattt ctcagctccc tggattcctt   2220

cccctaaatt aggacctatt atttacctgt aggtaagcaa gctactgtag ctcttctgag   2280

gtatctgcca ggctgttttc tgtagcctca gattgcctat ctgcttagcc tgagaacagg   2340

tagatgaaaa ctaaactgat gcctaggccc agggtcagtc tcagatggaa gctgggcctg   2400

ggtggggagg ctagcatgcg tggctccctg ggtatttctg tcagtcccca tggcaagcag   2460

tgatttagta aaacacccca gagtcaggga agccaaccac cttgaaacct ttagaacatc   2520

tctgctttgg agaaagaccc agagatcagg cagaggtgca gattcaatca ttactcataa   2580

cctttgagag atggcaaatg ggaggagtgt tagtctttgt tttggaattg gaccattctt   2640

gcaaccaaaa ggacttagag cagtttgctc ataaagacat cctttattat aaaaggaagt   2700

atttaaagga tgatagagac catcagatag aagcagggaa ggtagataac ttttaggacc   2760

ttgatgtgag gaaaagataa aatttaaaca ataaatttgc cacttagatt ttctagcagc   2820

aaagtccgaa aagatagtta tatacaaaat tctgttttct gaaaacaaaa ttgtgattca   2880

ccttcagaat tggccatttt ttttgtgagt ttccttgcat caaggacact gagaaacaca   2940

gtcattgtct taggtgttct atgggaggaa gtgaatagag cctttaggaa cttcctggtc   3000

aagcttatgg tgcttatttt gatctgggcc acttccctcc ttccagtcat gagtaatcat   3060

caaggagcaa gttggagtgt ttcaggtgta tattttgtag aacccaaaag attggagcct   3120

taacaataaa catcagcact aagtgacctg ttc                                3153


<210>  9486
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  9486

Met Cys Trp Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile Val 
1               5                   10                  15


Ser Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn Val 
            20                  25                  30


Ser Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val Asp 
        35                  40                  45


Pro Leu Arg Ile Pro Pro His His Pro His Thr Ser Arg Gln Pro Pro 
    50                  55                  60


Trp Cys Asp Pro Leu Gly Pro Phe Val Val Gly Gly Glu Asp Leu Asp 
65                  70                  75                  80


Pro Phe Gly Pro Arg Arg Gly Gly Met Ile Val Asp Pro Leu Arg Ser 
                85                  90                  95


Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn Arg 
            100                 105                 110


Leu Pro Pro Gly Ala Val Pro Pro Gly Ala Arg Phe Asp Pro Phe Gly 
        115                 120                 125


Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn Pro Asp His Leu Pro Pro 
    130                 135                 140


Pro Gly Tyr Asp Asp Met Tyr Leu 
145                 150


<210>  9487
<211>  4788
<212>  DNA
<213>  Homo sapiens

<400>  9487
ggcttccccg ccccgccccg tccccgggcg tctccatttt ggtctcaggt gtggactcgg     60

caagaaccag cgcaagaggg aagcagagtt atagctaccc cggccgcgga gccggctcac    120

tgcactaccc ccgccccctt ctttcctcca gacgccgaag tcgcgggcgc tcatggcggg    180

cctggagccg ggtcccaatg ataagaagtc agaactgctg ccagctgggt ggaacaacaa    240

taaagacctg tatgtcctcc ggtatgagta taaggatggg tccagaaagc tccttgtgaa    300

agccatcacc gtggagagca gcatgatcct caatgtgctg gaatatggct cacagcaagt    360

ggcagacttg accctgaact tggatgatta tatcgatgca gaacacctgg gtgacttcca    420

caggacctac aagaacagtg aggagcttcg gtctcgtatt gtgtctggaa tcatcacacc    480

tatccatgag cagtgggaaa aggctaatgt aagcagtccc caccgggagt tcccccctgc    540

taccgccaga gaggtggacc cactccggat tcctccacac cacccacaca ccagtcggca    600

gcctccctgg tgtgatcccc tgggcccgtt tgttgtcggg ggagaagact tagacccttt    660

tgggcctcgg agaggtggca tgattgtgga tcccctgaga tctggcttcc caagagcact    720

tattgaccct tcctcaggcc tcccgaaccg acttcctcca ggcgctgtgc ccccaggagc    780

tcgctttgac ccctttggac ccattgggac cagcccaccc ggacctaacc cagaccatct    840

ccccccgccg ggctacgatg acatgtacct gtgaaggcct caagaatgta acatcccagg    900

cttccctcca ttctcctgga gctgccaccg ctgtccccat cagcaaccat gttcttgcag    960

gctgggggca agggattctg ctcatgtgtt tgcagaccgg ctgggatagc ctccccaccc   1020

cttatcagag ccaagacacc tgctgcagct ctccacctag ctgcagatag ctcccaaaga   1080

gaaatcagtg tgtctctttc accatcagct cctccccttt caccaccagc tcctctccac   1140

ttcccaaggg agactccggc aaccttcagc aacatatatc ctcgaccaga tgcagtgcta   1200

taagaacaga acgcattttg gatgttatta ttaagaacca aatgtcaata cagaattcat   1260

gttgccggtt tcccactttt ctttttacat taatgcatag ctgcttccat ttatgagact   1320

ttagagtttg agtttctgta gggctgaatg actctttttc ctgcccaggg cccattcttg   1380

cttctcaggc accttccgtt tattaattgc cattgctcct gacatcacta agatgggtcc   1440

ccttctggct gcatgaatgg aaatgagtga ctggaaatcc cataggccac aagaatgact   1500

ttcacaaggg caggaacatt gtggaaagac tgcatcattc tgatgaggca aaatcctcca   1560

gctattcctg tctgggccag ttttgtaggt ccatctgtgc atgggcagca gtagtcaaaa   1620

agccaaggaa aaaacagagc agacctgaag gctaatctta tttttgccac taacttagtg   1680

aatgacccta agcaagttcc ttctcctctt agggccttgt gccaagccta tgaaattgga   1740

ggtggctttc ctgctctaaa gcattttgat gtctcattct gtgtttggta acccctataa   1800

actggggcag aggaaaagaa tgatggttca aggccatact tcccttgaac cttgtgtggt   1860

tcttgcctaa ctctgtggtt tttggacccc atggggccca gacagagcac aggagcatgg   1920

gctgcctctg agtgtggtgt tgaacttcgg gaggagcagg gagccctgca ccttgtgtcc   1980

tggcccacct gacctttggt gttctccgga tccttttcag cccgaggcct gacagacgcg   2040

ggcagtgatg agccctgttc tggagtggaa agagcacgat agagcaccag gctaagaggc   2100

acgagatcaa ggcggtagtc acttccgctc tgcagctagc atttcaacca tatgtggatc   2160

ctttcatttc tcagctccct ggattccttc ccctaaatta ggacctatta tttacctgta   2220

ggtaagcaag ctactgtagc tcttctgagg tatctgccag gctgttttct gtagcctcag   2280

attgcctatc tgcttagcct gagaacaggt agatgaaaac taaactgatg cctaggccca   2340

gggtcagtct cagatggaag ctgggcctgg gtggggaggc tagcatgcgt ggctccctgg   2400

gtatttctgt cagtccccat ggcaagcagt gatttagtaa aacaccccag agtcagggaa   2460

gccaaccacc ttgaaacctt tagaacatct ctgctttgga gaaagaccca gagatcaggc   2520

agaggtgcag attcaatcat tactcataac ctttgagaga tggcaaatgg gaggagtgtt   2580

agtctttgtt ttggaattgg accattcttg caaccaaaag gacttagagc agtttgctca   2640

taaagacatc ctttattata aaaggaagta tttaaaggat gatagagacc atcagataga   2700

agcagggaag gtagataact tttaggacct tgatgtgagg aaaagataaa atttaaacaa   2760

taaatttgcc acttagattt tctagcagca aagtccgaaa agatagttat atacaaaatt   2820

ctgttttctg aaaacaaaat tgtgattcac cttcagaatt ggccattttt tttgtgagtt   2880

tccttgcatc aaggacactg agaaacacag tcattgtctt aggtgttcta tgggaggaag   2940

tgaatagagc ctttaggaac ttcctggtca agcttatggt gcttattttg atctgggcca   3000

cttccctcct tccagtcatg agtaatcatc aaggagcaag ttggagtgtt tcaggtgtat   3060

attttgtaga acccaaaaga ttggagcctt aacaataaac atcagcacta agtgacctgt   3120

tcctcctttt ttaaatagca gctttattga gatataattt acatacccat aatttacata   3180

cctgtttaaa gtatacaatt cagtggattt agtatgttca cagtgttgca catccaccac   3240

catttctaat tcctgaacat tttcaccacc tcaaaaagaa accacacacc cattggcatg   3300

actccccatt cccttgctcc cagccccagg caaccactaa catctgtctc taaagatttt   3360

tttttttttt ctggacagtt ctcataagtg gaatcactca gtattatggc cttttgtgtc   3420

tggcttcttt catttcatgt gatgttttca agattcattc atgctgtagc atgtatccat   3480

ggtatggata tatcacattt tgcttatcct tttatcagtt gatggacagt tgggttgttt   3540

ctacaaaaag gctattatga gtaatgcagc caagaacatt tgtgtaccag tttttgagtt   3600

ttcagttgtt tgagtttcag atgttttcag ttcatttggg tatataccaa ggagtggaat   3660

tgctggttca catggtagct ctatattcta ctttgtgagg aattgtcaga ctgttttcca   3720

cggaagctgc accattttac atttccactg gtaatttatg agggttccag tttccccaca   3780

tcttcaccaa ctcttgttat ttttcatgct tatggccatc ctagttagcg tgaagtagca   3840

tctcattgtg gtcttctctt ccatttttta aaaaagaatt ttgacctaca ccaagcaagg   3900

cagagaccag agtcagtccc ccttggggag caatctgtgg ttttgataat caccaccttg   3960

ggatgaacat ggctggtgag ctgcagagca gttgatttga cttttgggga tggttctagg   4020

ctggatgtga tacagggcag gttttgtctc tagagaaagt tctcatgacc ttcaggtcta   4080

atgagattca gatcatcact ttggtttggt ttgaaatttc tttgtttatc cagtgaatta   4140

caagtagaat aaagatctgg ttctaaattg tcttttggtg gtgaagtgcc atagaccatt   4200

tcggaccatt tctatgatgt accagcagcc cccacatcac acctcctctt ccttggcttg   4260

tctcttcccc aattcttaga gttagcagtg tttcttactg cattcatctc ctcagtcata   4320

agtgtctgtc aacctccgtt gtgaagtcat gagtctcttg agactgaaac tccaagaatg   4380

tattgtgctc acagtggcga tggtgttcct gtgctggatg gtcagtggtt gttgacatgt   4440

agttagaaaa taggtagcaa gttccacgca gcctcactct ttggaaccta gtttctccta   4500

tggcctccct ttctactgtt gttaataaca ttctattaat gatccatgcc tctcttcaca   4560

ggaggaatat tagaatctat ggagcagtta gtattctttg tcacctaaat ttgtctactt   4620

ctgtacattt ccaataaggc accaccaggg caagggaaga ttccccacat gtatatcccc   4680

agctgtttct gtcataaaac ttgcatgtgt ataaaccact attgactttt tgcaccaaag   4740

gagatattca aggacagaca tccaagtccc cagcccttta ttgccctt                4788


<210>  9488
<211>  233
<212>  PRT
<213>  Homo sapiens

<400>  9488

Met Ala Gly Leu Glu Pro Gly Pro Asn Asp Lys Lys Ser Glu Leu Leu 
1               5                   10                  15


Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu Tyr Val Leu Arg Tyr Glu 
            20                  25                  30


Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val Lys Ala Ile Thr Val Glu 
        35                  40                  45


Ser Ser Met Ile Leu Asn Val Leu Glu Tyr Gly Ser Gln Gln Val Ala 
    50                  55                  60


Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile Asp Ala Glu His Leu Gly 
65                  70                  75                  80


Asp Phe His Arg Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile 
                85                  90                  95


Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn 
            100                 105                 110


Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val 
        115                 120                 125


Asp Pro Leu Arg Ile Pro Pro His His Pro His Thr Ser Arg Gln Pro 
    130                 135                 140


Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val Gly Gly Glu Asp Leu 
145                 150                 155                 160


Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile Val Asp Pro Leu Arg 
                165                 170                 175


Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn 
            180                 185                 190


Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala Arg Phe Asp Pro Phe 
        195                 200                 205


Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn Pro Asp His Leu Pro 
    210                 215                 220


Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
225                 230


<210>  9489
<211>  574
<212>  DNA
<213>  Homo sapiens

<400>  9489
cgccccgccc cgtccccggg cgtctccatt ttggtctcag gtgtggactc ggcaagaacc     60

agcgcaagag ggaagcagag ttatagctac cccggccgcg gagccggctc actgcactac    120

ccccgccccc ttctttcctc cagacgccga agtcgcgggc gctcatggcg ggcctggagc    180

cgggtcccaa tgataagaag tcagaactgc tgccagctgg gtggaacaac aataaagacc    240

tgtatgtcct ccggtatgag tataaggatg ggtccagaaa gctccttgtg aaagccatca    300

ccgtggagag cagcatgatc ctcaatgtgc tggaatatgg ctcacagcaa gtggcagact    360

tgaccctgaa cttggatgat tatatcgatg cagaacacct gggtgacttc cacaggacct    420

acaagaacag tgaggagctt cggtctcgta ttgtgtctgg aatcatcaca cctatccatg    480

agcagtggga aaaggctaat gtaagcagtc cccaccggga gttcccccct gctaccgcca    540

gagaggtgga cccactccgg attcctccac acca                                574


<210>  9490
<211>  135
<212>  PRT
<213>  Homo sapiens

<400>  9490

Met Ala Gly Leu Glu Pro Gly Pro Asn Asp Lys Lys Ser Glu Leu Leu 
1               5                   10                  15


Pro Ala Gly Trp Asn Asn Asn Lys Asp Leu Tyr Val Leu Arg Tyr Glu 
            20                  25                  30


Tyr Lys Asp Gly Ser Arg Lys Leu Leu Val Lys Ala Ile Thr Val Glu 
        35                  40                  45


Ser Ser Met Ile Leu Asn Val Leu Glu Tyr Gly Ser Gln Gln Val Ala 
    50                  55                  60


Asp Leu Thr Leu Asn Leu Asp Asp Tyr Ile Asp Ala Glu His Leu Gly 
65                  70                  75                  80


Asp Phe His Arg Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile 
                85                  90                  95


Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn 
            100                 105                 110


Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val 
        115                 120                 125


Asp Pro Leu Arg Ile Pro Pro 
    130                 135


<210>  9491
<211>  632
<212>  DNA
<213>  Homo sapiens

<400>  9491
cattttggtc tcaggtgtgg actcggcaag aaccagcgca agagggaagc agagttatag     60

ctaccccggc cgcggagccg gctcactgca ctacccccgc ccccttcgac ttcctccagg    120

cgctgtgccc ccaggagctc gctttgaccc ctttggaccc attgggacca gcccacccgg    180

acctaaccca gaccatctcc ccccgccggg ctacgatgac atgtacctgt gaaggcctca    240

agaatgtaac atcccaggct tccctccatt ctcctggagc tgccaccgct gtccccatca    300

gcaaccatgt tcttgcaggc tgggggcaag ggattctgct catgtgtttg cagaccggct    360

gggatagcct ccccacccct tatcagagcc aagacacctg ctgcagctct ccacctagct    420

gcagatagct cccaaagaga aatcagtgtg tctctttcac catcagctcc tcccctttca    480

ccaccagctc ctctccactt cccaagggag actccggcaa ccttcagcaa catatatcct    540

cgaccagatg cagtgctata agaacagaac gcattttgga tgttattatt aagaaccaaa    600

tgtcaataca gaattcatgt tgccggtttc cc                                  632


<210>  9492
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  9492

Met Phe Leu Gln Ala Gly Gly Lys Gly Phe Cys Ser Cys Val Cys Arg 
1               5                   10                  15


Pro Ala Gly Ile Ala Ser Pro Pro Leu Ile Arg Ala Lys Thr Pro Ala 
            20                  25                  30


Ala Ala Leu His Leu Ala Ala Asp Ser Ser Gln Arg Glu Ile Ser Val 
        35                  40                  45


Ser Leu Ser Pro Ser Ala Pro Pro Leu Ser Pro Pro Ala Pro Leu His 
    50                  55                  60


Phe Pro Arg Glu Thr Pro Ala Thr Phe Ser Asn Ile Tyr Pro Arg Pro 
65                  70                  75                  80


Asp Ala Val Leu 



<210>  9493
<211>  2480
<212>  DNA
<213>  Homo sapiens

<400>  9493
cattttggtc tcaggtgtgg actcggcaag aaccagcgca agagggaagc agagttatag     60

ctaccccggc cgcggagccg gctcactgca ctacccccgc ccccttcgac ttcctccagg    120

cgctgtgccc ccaggagctc gctttgaccc ctttggaccc attgggacca gcccacccgg    180

acctaaccca gaccatctcc ccccgccggg ctacgatgac atgtacctgt gaaggcctca    240

agaatgtaac atcccaggct tccctccatt ctcctggagc tgccaccgct gtccccatca    300

gcaaccatgt tcttgcaggc tgggggcaag ggattctgct catgtgtttg cagaccggct    360

gggatagcct ccccacccct tatcagagcc aagacacctg ctgcagctct ccacctagct    420

gcagatagct cccaaagaga aatcagtgtg tctctttcac catcagctcc tcccctttca    480

ccaccagctc ctctccactt cccaagggag actccggcaa ccttcagcaa catatatcct    540

cgaccagatg cagtgctata agaacagaac gcattttgga tgttattatt aagaaccaaa    600

tgtcaataca gaattcatgt tgccggtttc ccacttttct ttttacatta atgcatagct    660

gcttccattt atgagacttt agagtttgag tttctgtagg gctgaatgac tctttttcct    720

gcccagggcc cattcttgct tctcaggcac cttccgttta ttaattgcca ttgctcctga    780

catcactaag atgggtcccc ttctggctgc atgaatggaa atgagtgact ggaaatccca    840

taggccacaa gaatgacttt cacaagggca ggaacattgt ggaaagactg catcattctg    900

atgaggcaaa atcctccagc tattcctgtc tgggccagtt ttgtaggtcc atctgtgcat    960

gggcagcagt agtcaaaaag ccaaggaaaa aacagagcag acctgaaggc taatcttatt   1020

tttgccacta acttagtgaa tgaccctaag caagttcctt ctcctcttag ggccttgtgc   1080

caagcctatg aaattggagg tggctttcct gctctaaagc attttgatgt ctcattctgt   1140

gtttggtaac ccctataaac tggggcagag gaaaagaatg atggttcaag gccatacttc   1200

ccttgaacct tgtgtggttc ttgcctaact ctgtggtttt tggaccccat ggggcccaga   1260

cagagcacag gagcatgggc tgcctctgag tgtggtgttg aacttcggga ggagcaggga   1320

gccctgcacc ttgtgtcctg gcccacctga cctttggtgt tctccggatc cttttcagcc   1380

cgaggcctga cagacgcggg cagtgatgag ccctgttctg gagtggaaag agcacgatag   1440

agcaccaggc taagaggcac gagatcaagg cggtagtcac ttccgctctg cagctagcat   1500

ttcaaccata tgtggatcct ttcatttctc agctccctgg attccttccc ctaaattagg   1560

acctattatt tacctgtagg taagcaagct actgtagctc ttctgaggta tctgccaggc   1620

tgttttctgt agcctcagat tgcctatctg cttagcctga gaacaggtag atgaaaacta   1680

aactgatgcc taggcccagg gtcagtctca gatggaagct gggcctgggt ggggaggcta   1740

gcatgcgtgg ctccctgggt atttctgtca gtccccatgg caagcagtga tttagtaaaa   1800

caccccagag tcagggaagc caaccacctt gaaaccttta gaacatctct gctttggaga   1860

aagacccaga gatcaggcag aggtgcagat tcaatcatta ctcataacct ttgagagatg   1920

gcaaatggga ggagtgttag tctttgtttt ggaattggac cattcttgca accaaaagga   1980

cttagagcag tttgctcata aagacatcct ttattataaa aggaagtatt taaaggatga   2040

tagagaccat cagatagaag cagggaaggt agataacttt taggaccttg atgtgaggaa   2100

aagataaaat ttaaacaata aatttgccac ttagattttc tagcagcaaa gtccgaaaag   2160

atagttatat acaaaattct gttttctgaa aacaaaattg tgattcacct tcagaattgg   2220

ccattttttt tgtgagtttc cttgcatcaa ggacactgag aaacacagtc attgtcttag   2280

gtgttctatg ggaggaagtg aatagagcct ttaggaactt cctggtcaag cttatggtgc   2340

ttattttgat ctgggccact tccctccttc cagtcatgag taatcatcaa ggagcaagtt   2400

ggagtgtttc aggtgtatat tttgtagaac ccaaaagatt ggagccttaa caataaacat   2460

cagcactaag tgacctgttc                                               2480


<210>  9494
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  9494

Met Phe Leu Gln Ala Gly Gly Lys Gly Phe Cys Ser Cys Val Cys Arg 
1               5                   10                  15


Pro Ala Gly Ile Ala Ser Pro Pro Leu Ile Arg Ala Lys Thr Pro Ala 
            20                  25                  30


Ala Ala Leu His Leu Ala Ala Asp Ser Ser Gln Arg Glu Ile Ser Val 
        35                  40                  45


Ser Leu Ser Pro Ser Ala Pro Pro Leu Ser Pro Pro Ala Pro Leu His 
    50                  55                  60


Phe Pro Arg Glu Thr Pro Ala Thr Phe Ser Asn Ile Tyr Pro Arg Pro 
65                  70                  75                  80


Asp Ala Val Leu 



<210>  9495
<211>  4146
<212>  DNA
<213>  Homo sapiens

<400>  9495
cattttggtc tcaggtgtgg actcggcaag aaccagcgca agagggaagc agagttatag     60

ctaccccggc cgcggagccg gctcactgca ctacccccgc ccccttcgac ttcctccagg    120

cgctgtgccc ccaggagctc gctttgaccc ctttggaccc attgggacca gcccacccgg    180

acctaaccca gaccatctcc ccccgccggg ctacgatgac atgtacctgt gaaggcctca    240

agaatgtaac atcccaggct tccctccatt ctcctggagc tgccaccgct gtccccatca    300

gcaaccatgt tcttgcaggc tgggggcaag ggattctgct catgtgtttg cagaccggct    360

gggatagcct ccccacccct tatcagagcc aagacacctg ctgcagctct ccacctagct    420

gcagatagct cccaaagaga aatcagtgtg tctctttcac catcagctcc tcccctttca    480

ccaccagctc ctctccactt cccaagggag actccggcaa ccttcagcaa catatatcct    540

cgaccagatg cagtgctata agaacagaac gcattttgga tgttattatt aagaaccaaa    600

tgtcaataca gaattcatgt tgccggtttc ccacttttct ttttacatta atgcatagct    660

gcttccattt atgagacttt agagtttgag tttctgtagg gctgaatgac tctttttcct    720

gcccagggcc cattcttgct tctcaggcac cttccgttta ttaattgcca ttgctcctga    780

catcactaag atgggtcccc ttctggctgc atgaatggaa atgagtgact ggaaatccca    840

taggccacaa gaatgacttt cacaagggca ggaacattgt ggaaagactg catcattctg    900

atgaggcaaa atcctccagc tattcctgtc tgggccagtt ttgtaggtcc atctgtgcat    960

gggcagcagt agtcaaaaag ccaaggaaaa aacagagcag acctgaaggc taatcttatt   1020

tttgccacta acttagtgaa tgaccctaag caagttcctt ctcctcttag ggccttgtgc   1080

caagcctatg aaattggagg tggctttcct gctctaaagc attttgatgt ctcattctgt   1140

gtttggtaac ccctataaac tggggcagag gaaaagaatg atggttcaag gccatacttc   1200

ccttgaacct tgtgtggttc ttgcctaact ctgtggtttt tggaccccat ggggcccaga   1260

cagagcacag gagcatgggc tgcctctgag tgtggtgttg aacttcggga ggagcaggga   1320

gccctgcacc ttgtgtcctg gcccacctga cctttggtgt tctccggatc cttttcagcc   1380

cgaggcctga cagacgcggg cagtgatgag ccctgttctg gagtggaaag agcacgatag   1440

agcaccaggc taagaggcac gagatcaagg cggtagtcac ttccgctctg cagctagcat   1500

ttcaaccata tgtggatcct ttcatttctc agctccctgg attccttccc ctaaattagg   1560

acctattatt tacctgtagg taagcaagct actgtagctc ttctgaggta tctgccaggc   1620

tgttttctgt agcctcagat tgcctatctg cttagcctga gaacaggtag atgaaaacta   1680

aactgatgcc taggcccagg gtcagtctca gatggaagct gggcctgggt ggggaggcta   1740

gcatgcgtgg ctccctgggt atttctgtca gtccccatgg caagcagtga tttagtaaaa   1800

caccccagag tcagggaagc caaccacctt gaaaccttta gaacatctct gctttggaga   1860

aagacccaga gatcaggcag aggtgcagat tcaatcatta ctcataacct ttgagagatg   1920

gcaaatggga ggagtgttag tctttgtttt ggaattggac cattcttgca accaaaagga   1980

cttagagcag tttgctcata aagacatcct ttattataaa aggaagtatt taaaggatga   2040

tagagaccat cagatagaag cagggaaggt agataacttt taggaccttg atgtgaggaa   2100

aagataaaat ttaaacaata aatttgccac ttagattttc tagcagcaaa gtccgaaaag   2160

atagttatat acaaaattct gttttctgaa aacaaaattg tgattcacct tcagaattgg   2220

ccattttttt tgtgagtttc cttgcatcaa ggacactgag aaacacagtc attgtcttag   2280

gtgttctatg ggaggaagtg aatagagcct ttaggaactt cctggtcaag cttatggtgc   2340

ttattttgat ctgggccact tccctccttc cagtcatgag taatcatcaa ggagcaagtt   2400

ggagtgtttc aggtgtatat tttgtagaac ccaaaagatt ggagccttaa caataaacat   2460

cagcactaag tgacctgttc ctcctttttt aaatagcagc tttattgaga tataatttac   2520

atacccataa tttacatacc tgtttaaagt atacaattca gtggatttag tatgttcaca   2580

gtgttgcaca tccaccacca tttctaattc ctgaacattt tcaccacctc aaaaagaaac   2640

cacacaccca ttggcatgac tccccattcc cttgctccca gccccaggca accactaaca   2700

tctgtctcta aagatttttt ttttttttct ggacagttct cataagtgga atcactcagt   2760

attatggcct tttgtgtctg gcttctttca tttcatgtga tgttttcaag attcattcat   2820

gctgtagcat gtatccatgg tatggatata tcacattttg cttatccttt tatcagttga   2880

tggacagttg ggttgtttct acaaaaaggc tattatgagt aatgcagcca agaacatttg   2940

tgtaccagtt tttgagtttt cagttgtttg agtttcagat gttttcagtt catttgggta   3000

tataccaagg agtggaattg ctggttcaca tggtagctct atattctact ttgtgaggaa   3060

ttgtcagact gttttccacg gaagctgcac cattttacat ttccactggt aatttatgag   3120

ggttccagtt tccccacatc ttcaccaact cttgttattt ttcatgctta tggccatcct   3180

agttagcgtg aagtagcatc tcattgtggt cttctcttcc attttttaaa aaagaatttt   3240

gacctacacc aagcaaggca gagaccagag tcagtccccc ttggggagca atctgtggtt   3300

ttgataatca ccaccttggg atgaacatgg ctggtgagct gcagagcagt tgatttgact   3360

tttggggatg gttctaggct ggatgtgata cagggcaggt tttgtctcta gagaaagttc   3420

tcatgacctt caggtctaat gagattcaga tcatcacttt ggtttggttt gaaatttctt   3480

tgtttatcca gtgaattaca agtagaataa agatctggtt ctaaattgtc ttttggtggt   3540

gaagtgccat agaccatttc ggaccatttc tatgatgtac cagcagcccc cacatcacac   3600

ctcctcttcc ttggcttgtc tcttccccaa ttcttagagt tagcagtgtt tcttactgca   3660

ttcatctcct cagtcataag tgtctgtcaa cctccgttgt gaagtcatga gtctcttgag   3720

actgaaactc caagaatgta ttgtgctcac agtggcgatg gtgttcctgt gctggatggt   3780

cagtggttgt tgacatgtag ttagaaaata ggtagcaagt tccacgcagc ctcactcttt   3840

ggaacctagt ttctcctatg gcctcccttt ctactgttgt taataacatt ctattaatga   3900

tccatgcctc tcttcacagg aggaatatta gaatctatgg agcagttagt attctttgtc   3960

acctaaattt gtctacttct gtacatttcc aataaggcac caccagggca agggaagatt   4020

ccccacatgt atatccccag ctgtttctgt cataaaactt gcatgtgtat aaaccactat   4080

tgactttttg caccaaagga gatattcaag gacagacatc caagtcccca gccctttatt   4140

gccctt                                                              4146


<210>  9496
<211>  84
<212>  PRT
<213>  Homo sapiens

<400>  9496

Met Phe Leu Gln Ala Gly Gly Lys Gly Phe Cys Ser Cys Val Cys Arg 
1               5                   10                  15


Pro Ala Gly Ile Ala Ser Pro Pro Leu Ile Arg Ala Lys Thr Pro Ala 
            20                  25                  30


Ala Ala Leu His Leu Ala Ala Asp Ser Ser Gln Arg Glu Ile Ser Val 
        35                  40                  45


Ser Leu Ser Pro Ser Ala Pro Pro Leu Ser Pro Pro Ala Pro Leu His 
    50                  55                  60


Phe Pro Arg Glu Thr Pro Ala Thr Phe Ser Asn Ile Tyr Pro Arg Pro 
65                  70                  75                  80


Asp Ala Val Leu 



<210>  9497
<211>  337
<212>  DNA
<213>  Homo sapiens

<400>  9497
acctgtatgt cctccggtat gagtataagg atgggtccag aaagctcctt gtgaaagcca     60

tcaccgtgga gagcagcatg atcctcaatg tgctggaata tggctcacag caagtggcag    120

acttgaccct gaacttggat gattatatcg atgcagaaca cctgggtgac ttccacagga    180

cctacaagaa cagtgaggag cttcggtctc gtattgtgtc tggaatcatc acacctatcc    240

atgagcagtg ggaaaaggct aatgtaagca gtccccaccg ggagttcccc cctgctaccg    300

ccagagaggt ggacccactc cggattcctc cacacca                             337


<210>  9498
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  9498

Met Ile Leu Asn Val Leu Glu Tyr Gly Ser Gln Gln Val Ala Asp Leu 
1               5                   10                  15


Thr Leu Asn Leu Asp Asp Tyr Ile Asp Ala Glu His Leu Gly Asp Phe 
            20                  25                  30


His Arg Thr Tyr Lys Asn Ser Glu Glu Leu Arg Ser Arg Ile Val Ser 
        35                  40                  45


Gly Ile Ile Thr Pro Ile His Glu Gln Trp Glu Lys Ala Asn Val Ser 
    50                  55                  60


Ser Pro His Arg Glu Phe Pro Pro Ala Thr Ala Arg Glu Val Asp Pro 
65                  70                  75                  80


Leu Arg Ile Pro Pro 
                85


<210>  9499
<211>  1139
<212>  DNA
<213>  Homo sapiens

<400>  9499
aatccaggcc ctgtgcccct acaccctcac ctctttctaa tggggtggta aacaaggagg     60

ggcaactcag atgcctaaga agcttgggcc caaatctcag agacagcgtg gggctgttgc    120

ccccctcacc caggtccagc aggcggcctg ttcccccact tataaacagg ccaagcgcaa    180

tgccaggagc tatcagggcc gccgccgccg ccgtcgttgc agccagaata ccacttccag    240

ggttcctagc caactgcaag cagttgactc ttcatctgct tcctgcagga cctacaagaa    300

cagtgaggag cttcggtctc gtattgtgtc tggaatcatc acacctatcc atgagcagtg    360

ggaaaaggct aatgtaagca gtccccaccg ggagttcccc cctgctaccg ccagagaggt    420

ggacccactc cggattcctc cacaccaccc acacaccagt cggcagcctc cctggtgtga    480

tcccctgggc ccgtttgttg tcgggggaga agacttagac ccttttgggc ctcggagagg    540

tggcatgatt gtggatcccc tgagatctgg cttcccaaga gcacttattg acccttcctc    600

aggcctcccg aaccgacttc ctccaggcgc tgtgccccca ggagctcgct ttgacccctt    660

tggacccatt gggaccagcc cacccggacc taacccagac catctccccc cgccgggcta    720

cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc ccaggcttcc ctccattctc    780

ctggagctgc caccgctgtc cccatcagca accatgttct tgcaggctgg gggcaaggga    840

ttctgctcat gtgtttgcag accggctggg atagcctccc caccccttat cagagccaag    900

acacctgctg cagctctcca cctagctgca gatagctccc aaagagaaat cagtgtgtct    960

ctttcaccat cagctcctcc cctttcacca ccagctcctc tccacttccc aagggagact   1020

ccggcaacct tcagcaacat atatcctcga ccagatgcag tgctataaga acagaacgca   1080

ttttggatgt tattattaag aaccaaatgt caatacagaa ttcatgttgc cggtttccc    1139


<210>  9500
<211>  222
<212>  PRT
<213>  Homo sapiens

<400>  9500

Met Pro Lys Lys Leu Gly Pro Lys Ser Gln Arg Gln Arg Gly Ala Val 
1               5                   10                  15


Ala Pro Leu Thr Gln Val Gln Gln Ala Ala Cys Ser Pro Thr Tyr Lys 
            20                  25                  30


Gln Ala Lys Arg Asn Ala Arg Ser Tyr Gln Gly Arg Arg Arg Arg Arg 
        35                  40                  45


Arg Cys Ser Gln Asn Thr Thr Ser Arg Val Pro Ser Gln Leu Gln Ala 
    50                  55                  60


Val Asp Ser Ser Ser Ala Ser Cys Arg Thr Tyr Lys Asn Ser Glu Glu 
65                  70                  75                  80


Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln 
                85                  90                  95


Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala 
            100                 105                 110


Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro His 
        115                 120                 125


Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val 
    130                 135                 140


Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile 
145                 150                 155                 160


Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser 
                165                 170                 175


Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala 
            180                 185                 190


Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn 
        195                 200                 205


Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
    210                 215                 220


<210>  9501
<211>  2987
<212>  DNA
<213>  Homo sapiens

<400>  9501
aatccaggcc ctgtgcccct acaccctcac ctctttctaa tggggtggta aacaaggagg     60

ggcaactcag atgcctaaga agcttgggcc caaatctcag agacagcgtg gggctgttgc    120

ccccctcacc caggtccagc aggcggcctg ttcccccact tataaacagg ccaagcgcaa    180

tgccaggagc tatcagggcc gccgccgccg ccgtcgttgc agccagaata ccacttccag    240

ggttcctagc caactgcaag cagttgactc ttcatctgct tcctgcagga cctacaagaa    300

cagtgaggag cttcggtctc gtattgtgtc tggaatcatc acacctatcc atgagcagtg    360

ggaaaaggct aatgtaagca gtccccaccg ggagttcccc cctgctaccg ccagagaggt    420

ggacccactc cggattcctc cacaccaccc acacaccagt cggcagcctc cctggtgtga    480

tcccctgggc ccgtttgttg tcgggggaga agacttagac ccttttgggc ctcggagagg    540

tggcatgatt gtggatcccc tgagatctgg cttcccaaga gcacttattg acccttcctc    600

aggcctcccg aaccgacttc ctccaggcgc tgtgccccca ggagctcgct ttgacccctt    660

tggacccatt gggaccagcc cacccggacc taacccagac catctccccc cgccgggcta    720

cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc ccaggcttcc ctccattctc    780

ctggagctgc caccgctgtc cccatcagca accatgttct tgcaggctgg gggcaaggga    840

ttctgctcat gtgtttgcag accggctggg atagcctccc caccccttat cagagccaag    900

acacctgctg cagctctcca cctagctgca gatagctccc aaagagaaat cagtgtgtct    960

ctttcaccat cagctcctcc cctttcacca ccagctcctc tccacttccc aagggagact   1020

ccggcaacct tcagcaacat atatcctcga ccagatgcag tgctataaga acagaacgca   1080

ttttggatgt tattattaag aaccaaatgt caatacagaa ttcatgttgc cggtttccca   1140

cttttctttt tacattaatg catagctgct tccatttatg agactttaga gtttgagttt   1200

ctgtagggct gaatgactct ttttcctgcc cagggcccat tcttgcttct caggcacctt   1260

ccgtttatta attgccattg ctcctgacat cactaagatg ggtccccttc tggctgcatg   1320

aatggaaatg agtgactgga aatcccatag gccacaagaa tgactttcac aagggcagga   1380

acattgtgga aagactgcat cattctgatg aggcaaaatc ctccagctat tcctgtctgg   1440

gccagttttg taggtccatc tgtgcatggg cagcagtagt caaaaagcca aggaaaaaac   1500

agagcagacc tgaaggctaa tcttattttt gccactaact tagtgaatga ccctaagcaa   1560

gttccttctc ctcttagggc cttgtgccaa gcctatgaaa ttggaggtgg ctttcctgct   1620

ctaaagcatt ttgatgtctc attctgtgtt tggtaacccc tataaactgg ggcagaggaa   1680

aagaatgatg gttcaaggcc atacttccct tgaaccttgt gtggttcttg cctaactctg   1740

tggtttttgg accccatggg gcccagacag agcacaggag catgggctgc ctctgagtgt   1800

ggtgttgaac ttcgggagga gcagggagcc ctgcaccttg tgtcctggcc cacctgacct   1860

ttggtgttct ccggatcctt ttcagcccga ggcctgacag acgcgggcag tgatgagccc   1920

tgttctggag tggaaagagc acgatagagc accaggctaa gaggcacgag atcaaggcgg   1980

tagtcacttc cgctctgcag ctagcatttc aaccatatgt ggatcctttc atttctcagc   2040

tccctggatt ccttccccta aattaggacc tattatttac ctgtaggtaa gcaagctact   2100

gtagctcttc tgaggtatct gccaggctgt tttctgtagc ctcagattgc ctatctgctt   2160

agcctgagaa caggtagatg aaaactaaac tgatgcctag gcccagggtc agtctcagat   2220

ggaagctggg cctgggtggg gaggctagca tgcgtggctc cctgggtatt tctgtcagtc   2280

cccatggcaa gcagtgattt agtaaaacac cccagagtca gggaagccaa ccaccttgaa   2340

acctttagaa catctctgct ttggagaaag acccagagat caggcagagg tgcagattca   2400

atcattactc ataacctttg agagatggca aatgggagga gtgttagtct ttgttttgga   2460

attggaccat tcttgcaacc aaaaggactt agagcagttt gctcataaag acatccttta   2520

ttataaaagg aagtatttaa aggatgatag agaccatcag atagaagcag ggaaggtaga   2580

taacttttag gaccttgatg tgaggaaaag ataaaattta aacaataaat ttgccactta   2640

gattttctag cagcaaagtc cgaaaagata gttatataca aaattctgtt ttctgaaaac   2700

aaaattgtga ttcaccttca gaattggcca ttttttttgt gagtttcctt gcatcaagga   2760

cactgagaaa cacagtcatt gtcttaggtg ttctatggga ggaagtgaat agagccttta   2820

ggaacttcct ggtcaagctt atggtgctta ttttgatctg ggccacttcc ctccttccag   2880

tcatgagtaa tcatcaagga gcaagttgga gtgtttcagg tgtatatttt gtagaaccca   2940

aaagattgga gccttaacaa taaacatcag cactaagtga cctgttc                 2987


<210>  9502
<211>  222
<212>  PRT
<213>  Homo sapiens

<400>  9502

Met Pro Lys Lys Leu Gly Pro Lys Ser Gln Arg Gln Arg Gly Ala Val 
1               5                   10                  15


Ala Pro Leu Thr Gln Val Gln Gln Ala Ala Cys Ser Pro Thr Tyr Lys 
            20                  25                  30


Gln Ala Lys Arg Asn Ala Arg Ser Tyr Gln Gly Arg Arg Arg Arg Arg 
        35                  40                  45


Arg Cys Ser Gln Asn Thr Thr Ser Arg Val Pro Ser Gln Leu Gln Ala 
    50                  55                  60


Val Asp Ser Ser Ser Ala Ser Cys Arg Thr Tyr Lys Asn Ser Glu Glu 
65                  70                  75                  80


Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln 
                85                  90                  95


Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala 
            100                 105                 110


Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro His 
        115                 120                 125


Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val 
    130                 135                 140


Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile 
145                 150                 155                 160


Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser 
                165                 170                 175


Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala 
            180                 185                 190


Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn 
        195                 200                 205


Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
    210                 215                 220


<210>  9503
<211>  4653
<212>  DNA
<213>  Homo sapiens

<400>  9503
aatccaggcc ctgtgcccct acaccctcac ctctttctaa tggggtggta aacaaggagg     60

ggcaactcag atgcctaaga agcttgggcc caaatctcag agacagcgtg gggctgttgc    120

ccccctcacc caggtccagc aggcggcctg ttcccccact tataaacagg ccaagcgcaa    180

tgccaggagc tatcagggcc gccgccgccg ccgtcgttgc agccagaata ccacttccag    240

ggttcctagc caactgcaag cagttgactc ttcatctgct tcctgcagga cctacaagaa    300

cagtgaggag cttcggtctc gtattgtgtc tggaatcatc acacctatcc atgagcagtg    360

ggaaaaggct aatgtaagca gtccccaccg ggagttcccc cctgctaccg ccagagaggt    420

ggacccactc cggattcctc cacaccaccc acacaccagt cggcagcctc cctggtgtga    480

tcccctgggc ccgtttgttg tcgggggaga agacttagac ccttttgggc ctcggagagg    540

tggcatgatt gtggatcccc tgagatctgg cttcccaaga gcacttattg acccttcctc    600

aggcctcccg aaccgacttc ctccaggcgc tgtgccccca ggagctcgct ttgacccctt    660

tggacccatt gggaccagcc cacccggacc taacccagac catctccccc cgccgggcta    720

cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc ccaggcttcc ctccattctc    780

ctggagctgc caccgctgtc cccatcagca accatgttct tgcaggctgg gggcaaggga    840

ttctgctcat gtgtttgcag accggctggg atagcctccc caccccttat cagagccaag    900

acacctgctg cagctctcca cctagctgca gatagctccc aaagagaaat cagtgtgtct    960

ctttcaccat cagctcctcc cctttcacca ccagctcctc tccacttccc aagggagact   1020

ccggcaacct tcagcaacat atatcctcga ccagatgcag tgctataaga acagaacgca   1080

ttttggatgt tattattaag aaccaaatgt caatacagaa ttcatgttgc cggtttccca   1140

cttttctttt tacattaatg catagctgct tccatttatg agactttaga gtttgagttt   1200

ctgtagggct gaatgactct ttttcctgcc cagggcccat tcttgcttct caggcacctt   1260

ccgtttatta attgccattg ctcctgacat cactaagatg ggtccccttc tggctgcatg   1320

aatggaaatg agtgactgga aatcccatag gccacaagaa tgactttcac aagggcagga   1380

acattgtgga aagactgcat cattctgatg aggcaaaatc ctccagctat tcctgtctgg   1440

gccagttttg taggtccatc tgtgcatggg cagcagtagt caaaaagcca aggaaaaaac   1500

agagcagacc tgaaggctaa tcttattttt gccactaact tagtgaatga ccctaagcaa   1560

gttccttctc ctcttagggc cttgtgccaa gcctatgaaa ttggaggtgg ctttcctgct   1620

ctaaagcatt ttgatgtctc attctgtgtt tggtaacccc tataaactgg ggcagaggaa   1680

aagaatgatg gttcaaggcc atacttccct tgaaccttgt gtggttcttg cctaactctg   1740

tggtttttgg accccatggg gcccagacag agcacaggag catgggctgc ctctgagtgt   1800

ggtgttgaac ttcgggagga gcagggagcc ctgcaccttg tgtcctggcc cacctgacct   1860

ttggtgttct ccggatcctt ttcagcccga ggcctgacag acgcgggcag tgatgagccc   1920

tgttctggag tggaaagagc acgatagagc accaggctaa gaggcacgag atcaaggcgg   1980

tagtcacttc cgctctgcag ctagcatttc aaccatatgt ggatcctttc atttctcagc   2040

tccctggatt ccttccccta aattaggacc tattatttac ctgtaggtaa gcaagctact   2100

gtagctcttc tgaggtatct gccaggctgt tttctgtagc ctcagattgc ctatctgctt   2160

agcctgagaa caggtagatg aaaactaaac tgatgcctag gcccagggtc agtctcagat   2220

ggaagctggg cctgggtggg gaggctagca tgcgtggctc cctgggtatt tctgtcagtc   2280

cccatggcaa gcagtgattt agtaaaacac cccagagtca gggaagccaa ccaccttgaa   2340

acctttagaa catctctgct ttggagaaag acccagagat caggcagagg tgcagattca   2400

atcattactc ataacctttg agagatggca aatgggagga gtgttagtct ttgttttgga   2460

attggaccat tcttgcaacc aaaaggactt agagcagttt gctcataaag acatccttta   2520

ttataaaagg aagtatttaa aggatgatag agaccatcag atagaagcag ggaaggtaga   2580

taacttttag gaccttgatg tgaggaaaag ataaaattta aacaataaat ttgccactta   2640

gattttctag cagcaaagtc cgaaaagata gttatataca aaattctgtt ttctgaaaac   2700

aaaattgtga ttcaccttca gaattggcca ttttttttgt gagtttcctt gcatcaagga   2760

cactgagaaa cacagtcatt gtcttaggtg ttctatggga ggaagtgaat agagccttta   2820

ggaacttcct ggtcaagctt atggtgctta ttttgatctg ggccacttcc ctccttccag   2880

tcatgagtaa tcatcaagga gcaagttgga gtgtttcagg tgtatatttt gtagaaccca   2940

aaagattgga gccttaacaa taaacatcag cactaagtga cctgttcctc cttttttaaa   3000

tagcagcttt attgagatat aatttacata cccataattt acatacctgt ttaaagtata   3060

caattcagtg gatttagtat gttcacagtg ttgcacatcc accaccattt ctaattcctg   3120

aacattttca ccacctcaaa aagaaaccac acacccattg gcatgactcc ccattccctt   3180

gctcccagcc ccaggcaacc actaacatct gtctctaaag attttttttt tttttctgga   3240

cagttctcat aagtggaatc actcagtatt atggcctttt gtgtctggct tctttcattt   3300

catgtgatgt tttcaagatt cattcatgct gtagcatgta tccatggtat ggatatatca   3360

cattttgctt atccttttat cagttgatgg acagttgggt tgtttctaca aaaaggctat   3420

tatgagtaat gcagccaaga acatttgtgt accagttttt gagttttcag ttgtttgagt   3480

ttcagatgtt ttcagttcat ttgggtatat accaaggagt ggaattgctg gttcacatgg   3540

tagctctata ttctactttg tgaggaattg tcagactgtt ttccacggaa gctgcaccat   3600

tttacatttc cactggtaat ttatgagggt tccagtttcc ccacatcttc accaactctt   3660

gttatttttc atgcttatgg ccatcctagt tagcgtgaag tagcatctca ttgtggtctt   3720

ctcttccatt ttttaaaaaa gaattttgac ctacaccaag caaggcagag accagagtca   3780

gtcccccttg gggagcaatc tgtggttttg ataatcacca ccttgggatg aacatggctg   3840

gtgagctgca gagcagttga tttgactttt ggggatggtt ctaggctgga tgtgatacag   3900

ggcaggtttt gtctctagag aaagttctca tgaccttcag gtctaatgag attcagatca   3960

tcactttggt ttggtttgaa atttctttgt ttatccagtg aattacaagt agaataaaga   4020

tctggttcta aattgtcttt tggtggtgaa gtgccataga ccatttcgga ccatttctat   4080

gatgtaccag cagcccccac atcacacctc ctcttccttg gcttgtctct tccccaattc   4140

ttagagttag cagtgtttct tactgcattc atctcctcag tcataagtgt ctgtcaacct   4200

ccgttgtgaa gtcatgagtc tcttgagact gaaactccaa gaatgtattg tgctcacagt   4260

ggcgatggtg ttcctgtgct ggatggtcag tggttgttga catgtagtta gaaaataggt   4320

agcaagttcc acgcagcctc actctttgga acctagtttc tcctatggcc tccctttcta   4380

ctgttgttaa taacattcta ttaatgatcc atgcctctct tcacaggagg aatattagaa   4440

tctatggagc agttagtatt ctttgtcacc taaatttgtc tacttctgta catttccaat   4500

aaggcaccac cagggcaagg gaagattccc cacatgtata tccccagctg tttctgtcat   4560

aaaacttgca tgtgtataaa ccactattga ctttttgcac caaaggagat attcaaggac   4620

agacatccaa gtccccagcc ctttattgcc ctt                                4653


<210>  9504
<211>  222
<212>  PRT
<213>  Homo sapiens

<400>  9504

Met Pro Lys Lys Leu Gly Pro Lys Ser Gln Arg Gln Arg Gly Ala Val 
1               5                   10                  15


Ala Pro Leu Thr Gln Val Gln Gln Ala Ala Cys Ser Pro Thr Tyr Lys 
            20                  25                  30


Gln Ala Lys Arg Asn Ala Arg Ser Tyr Gln Gly Arg Arg Arg Arg Arg 
        35                  40                  45


Arg Cys Ser Gln Asn Thr Thr Ser Arg Val Pro Ser Gln Leu Gln Ala 
    50                  55                  60


Val Asp Ser Ser Ser Ala Ser Cys Arg Thr Tyr Lys Asn Ser Glu Glu 
65                  70                  75                  80


Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln 
                85                  90                  95


Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala 
            100                 105                 110


Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro His His Pro His 
        115                 120                 125


Thr Ser Arg Gln Pro Pro Trp Cys Asp Pro Leu Gly Pro Phe Val Val 
    130                 135                 140


Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg Arg Gly Gly Met Ile 
145                 150                 155                 160


Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala Leu Ile Asp Pro Ser 
                165                 170                 175


Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala Val Pro Pro Gly Ala 
            180                 185                 190


Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser Pro Pro Gly Pro Asn 
        195                 200                 205


Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp Met Tyr Leu 
    210                 215                 220


<210>  9505
<211>  2441
<212>  DNA
<213>  Homo sapiens

<400>  9505
cagatgccta agaagcttgg gcccaaatct cagagacagc gtggggctgt tgcccccctc     60

acccaggtcc agcaggcggc ctgttccccc acttataaac aggccaagcg caatgccagg    120

agctatcagg gccgccgccg ccgccgtcgt tgcagccaga ataccacttc cagggttcct    180

agccaactgc aagcagttga ctcttcatct gcttcctgca ggacctacaa gaacagtgag    240

gagcttcggt ctcgtattgt gtctggaatc atcacaccta tccatgagca gtgggaaaag    300

gctaatgtaa gcagtcccca ccgggagttc ccccctgcta ccgccagaga ggtggaccca    360

ctccggattc ctccactagc tgcagatagc tcccaaagag aaatcagtgt gtctctttca    420

ccatcagctc ctcccctttc accaccagct cctctccact tcccaaggga gactccggca    480

accttcagca acatatatcc tcgaccagat gcagtgctat aagaacagaa cgcattttgg    540

atgttattat taagaaccaa atgtcaatac agaattcatg ttgccggttt cccacttttc    600

tttttacatt aatgcatagc tgcttccatt tatgagactt tagagtttga gtttctgtag    660

ggctgaatga ctctttttcc tgcccagggc ccattcttgc ttctcaggca ccttccgttt    720

attaattgcc attgctcctg acatcactaa gatgggtccc cttctggctg catgaatgga    780

aatgagtgac tggaaatccc ataggccaca agaatgactt tcacaagggc aggaacattg    840

tggaaagact gcatcattct gatgaggcaa aatcctccag ctattcctgt ctgggccagt    900

tttgtaggtc catctgtgca tgggcagcag tagtcaaaaa gccaaggaaa aaacagagca    960

gacctgaagg ctaatcttat ttttgccact aacttagtga atgaccctaa gcaagttcct   1020

tctcctctta gggccttgtg ccaagcctat gaaattggag gtggctttcc tgctctaaag   1080

cattttgatg tctcattctg tgtttggtaa cccctataaa ctggggcaga ggaaaagaat   1140

gatggttcaa ggccatactt cccttgaacc ttgtgtggtt cttgcctaac tctgtggttt   1200

ttggacccca tggggcccag acagagcaca ggagcatggg ctgcctctga gtgtggtgtt   1260

gaacttcggg aggagcaggg agccctgcac cttgtgtcct ggcccacctg acctttggtg   1320

ttctccggat ccttttcagc ccgaggcctg acagacgcgg gcagtgatga gccctgttct   1380

ggagtggaaa gagcacgata gagcaccagg ctaagaggca cgagatcaag gcggtagtca   1440

cttccgctct gcagctagca tttcaaccat atgtggatcc tttcatttct cagctccctg   1500

gattccttcc cctaaattag gacctattat ttacctgtag gtaagcaagc tactgtagct   1560

cttctgaggt atctgccagg ctgttttctg tagcctcaga ttgcctatct gcttagcctg   1620

agaacaggta gatgaaaact aaactgatgc ctaggcccag ggtcagtctc agatggaagc   1680

tgggcctggg tggggaggct agcatgcgtg gctccctggg tatttctgtc agtccccatg   1740

gcaagcagtg atttagtaaa acaccccaga gtcagggaag ccaaccacct tgaaaccttt   1800

agaacatctc tgctttggag aaagacccag agatcaggca gaggtgcaga ttcaatcatt   1860

actcataacc tttgagagat ggcaaatggg aggagtgtta gtctttgttt tggaattgga   1920

ccattcttgc aaccaaaagg acttagagca gtttgctcat aaagacatcc tttattataa   1980

aaggaagtat ttaaaggatg atagagacca tcagatagaa gcagggaagg tagataactt   2040

ttaggacctt gatgtgagga aaagataaaa tttaaacaat aaatttgcca cttagatttt   2100

ctagcagcaa agtccgaaaa gatagttata tacaaaattc tgttttctga aaacaaaatt   2160

gtgattcacc ttcagaattg gccatttttt ttgtgagttt ccttgcatca aggacactga   2220

gaaacacagt cattgtctta ggtgttctat gggaggaagt gaatagagcc tttaggaact   2280

tcctggtcaa gcttatggtg cttattttga tctgggccac ttccctcctt ccagtcatga   2340

gtaatcatca aggagcaagt tggagtgttt caggtgtata ttttgtagaa cccaaaagat   2400

tggagcctta acaataaaca tcagcactaa gtgacctgtt c                       2441


<210>  9506
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  9506

Met Pro Lys Lys Leu Gly Pro Lys Ser Gln Arg Gln Arg Gly Ala Val 
1               5                   10                  15


Ala Pro Leu Thr Gln Val Gln Gln Ala Ala Cys Ser Pro Thr Tyr Lys 
            20                  25                  30


Gln Ala Lys Arg Asn Ala Arg Ser Tyr Gln Gly Arg Arg Arg Arg Arg 
        35                  40                  45


Arg Cys Ser Gln Asn Thr Thr Ser Arg Val Pro Ser Gln Leu Gln Ala 
    50                  55                  60


Val Asp Ser Ser Ser Ala Ser Cys Arg Thr Tyr Lys Asn Ser Glu Glu 
65                  70                  75                  80


Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln 
                85                  90                  95


Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala 
            100                 105                 110


Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro Leu Ala Ala Asp 
        115                 120                 125


Ser Ser Gln Arg Glu Ile Ser Val Ser Leu Ser Pro Ser Ala Pro Pro 
    130                 135                 140


Leu Ser Pro Pro Ala Pro Leu His Phe Pro Arg Glu Thr Pro Ala Thr 
145                 150                 155                 160


Phe Ser Asn Ile Tyr Pro Arg Pro Asp Ala Val Leu 
                165                 170


<210>  9507
<211>  4107
<212>  DNA
<213>  Homo sapiens

<400>  9507
cagatgccta agaagcttgg gcccaaatct cagagacagc gtggggctgt tgcccccctc     60

acccaggtcc agcaggcggc ctgttccccc acttataaac aggccaagcg caatgccagg    120

agctatcagg gccgccgccg ccgccgtcgt tgcagccaga ataccacttc cagggttcct    180

agccaactgc aagcagttga ctcttcatct gcttcctgca ggacctacaa gaacagtgag    240

gagcttcggt ctcgtattgt gtctggaatc atcacaccta tccatgagca gtgggaaaag    300

gctaatgtaa gcagtcccca ccgggagttc ccccctgcta ccgccagaga ggtggaccca    360

ctccggattc ctccactagc tgcagatagc tcccaaagag aaatcagtgt gtctctttca    420

ccatcagctc ctcccctttc accaccagct cctctccact tcccaaggga gactccggca    480

accttcagca acatatatcc tcgaccagat gcagtgctat aagaacagaa cgcattttgg    540

atgttattat taagaaccaa atgtcaatac agaattcatg ttgccggttt cccacttttc    600

tttttacatt aatgcatagc tgcttccatt tatgagactt tagagtttga gtttctgtag    660

ggctgaatga ctctttttcc tgcccagggc ccattcttgc ttctcaggca ccttccgttt    720

attaattgcc attgctcctg acatcactaa gatgggtccc cttctggctg catgaatgga    780

aatgagtgac tggaaatccc ataggccaca agaatgactt tcacaagggc aggaacattg    840

tggaaagact gcatcattct gatgaggcaa aatcctccag ctattcctgt ctgggccagt    900

tttgtaggtc catctgtgca tgggcagcag tagtcaaaaa gccaaggaaa aaacagagca    960

gacctgaagg ctaatcttat ttttgccact aacttagtga atgaccctaa gcaagttcct   1020

tctcctctta gggccttgtg ccaagcctat gaaattggag gtggctttcc tgctctaaag   1080

cattttgatg tctcattctg tgtttggtaa cccctataaa ctggggcaga ggaaaagaat   1140

gatggttcaa ggccatactt cccttgaacc ttgtgtggtt cttgcctaac tctgtggttt   1200

ttggacccca tggggcccag acagagcaca ggagcatggg ctgcctctga gtgtggtgtt   1260

gaacttcggg aggagcaggg agccctgcac cttgtgtcct ggcccacctg acctttggtg   1320

ttctccggat ccttttcagc ccgaggcctg acagacgcgg gcagtgatga gccctgttct   1380

ggagtggaaa gagcacgata gagcaccagg ctaagaggca cgagatcaag gcggtagtca   1440

cttccgctct gcagctagca tttcaaccat atgtggatcc tttcatttct cagctccctg   1500

gattccttcc cctaaattag gacctattat ttacctgtag gtaagcaagc tactgtagct   1560

cttctgaggt atctgccagg ctgttttctg tagcctcaga ttgcctatct gcttagcctg   1620

agaacaggta gatgaaaact aaactgatgc ctaggcccag ggtcagtctc agatggaagc   1680

tgggcctggg tggggaggct agcatgcgtg gctccctggg tatttctgtc agtccccatg   1740

gcaagcagtg atttagtaaa acaccccaga gtcagggaag ccaaccacct tgaaaccttt   1800

agaacatctc tgctttggag aaagacccag agatcaggca gaggtgcaga ttcaatcatt   1860

actcataacc tttgagagat ggcaaatggg aggagtgtta gtctttgttt tggaattgga   1920

ccattcttgc aaccaaaagg acttagagca gtttgctcat aaagacatcc tttattataa   1980

aaggaagtat ttaaaggatg atagagacca tcagatagaa gcagggaagg tagataactt   2040

ttaggacctt gatgtgagga aaagataaaa tttaaacaat aaatttgcca cttagatttt   2100

ctagcagcaa agtccgaaaa gatagttata tacaaaattc tgttttctga aaacaaaatt   2160

gtgattcacc ttcagaattg gccatttttt ttgtgagttt ccttgcatca aggacactga   2220

gaaacacagt cattgtctta ggtgttctat gggaggaagt gaatagagcc tttaggaact   2280

tcctggtcaa gcttatggtg cttattttga tctgggccac ttccctcctt ccagtcatga   2340

gtaatcatca aggagcaagt tggagtgttt caggtgtata ttttgtagaa cccaaaagat   2400

tggagcctta acaataaaca tcagcactaa gtgacctgtt cctccttttt taaatagcag   2460

ctttattgag atataattta catacccata atttacatac ctgtttaaag tatacaattc   2520

agtggattta gtatgttcac agtgttgcac atccaccacc atttctaatt cctgaacatt   2580

ttcaccacct caaaaagaaa ccacacaccc attggcatga ctccccattc ccttgctccc   2640

agccccaggc aaccactaac atctgtctct aaagattttt tttttttttc tggacagttc   2700

tcataagtgg aatcactcag tattatggcc ttttgtgtct ggcttctttc atttcatgtg   2760

atgttttcaa gattcattca tgctgtagca tgtatccatg gtatggatat atcacatttt   2820

gcttatcctt ttatcagttg atggacagtt gggttgtttc tacaaaaagg ctattatgag   2880

taatgcagcc aagaacattt gtgtaccagt ttttgagttt tcagttgttt gagtttcaga   2940

tgttttcagt tcatttgggt atataccaag gagtggaatt gctggttcac atggtagctc   3000

tatattctac tttgtgagga attgtcagac tgttttccac ggaagctgca ccattttaca   3060

tttccactgg taatttatga gggttccagt ttccccacat cttcaccaac tcttgttatt   3120

tttcatgctt atggccatcc tagttagcgt gaagtagcat ctcattgtgg tcttctcttc   3180

cattttttaa aaaagaattt tgacctacac caagcaaggc agagaccaga gtcagtcccc   3240

cttggggagc aatctgtggt tttgataatc accaccttgg gatgaacatg gctggtgagc   3300

tgcagagcag ttgatttgac ttttggggat ggttctaggc tggatgtgat acagggcagg   3360

ttttgtctct agagaaagtt ctcatgacct tcaggtctaa tgagattcag atcatcactt   3420

tggtttggtt tgaaatttct ttgtttatcc agtgaattac aagtagaata aagatctggt   3480

tctaaattgt cttttggtgg tgaagtgcca tagaccattt cggaccattt ctatgatgta   3540

ccagcagccc ccacatcaca cctcctcttc cttggcttgt ctcttcccca attcttagag   3600

ttagcagtgt ttcttactgc attcatctcc tcagtcataa gtgtctgtca acctccgttg   3660

tgaagtcatg agtctcttga gactgaaact ccaagaatgt attgtgctca cagtggcgat   3720

ggtgttcctg tgctggatgg tcagtggttg ttgacatgta gttagaaaat aggtagcaag   3780

ttccacgcag cctcactctt tggaacctag tttctcctat ggcctccctt tctactgttg   3840

ttaataacat tctattaatg atccatgcct ctcttcacag gaggaatatt agaatctatg   3900

gagcagttag tattctttgt cacctaaatt tgtctacttc tgtacatttc caataaggca   3960

ccaccagggc aagggaagat tccccacatg tatatcccca gctgtttctg tcataaaact   4020

tgcatgtgta taaaccacta ttgacttttt gcaccaaagg agatattcaa ggacagacat   4080

ccaagtcccc agccctttat tgccctt                                       4107


<210>  9508
<211>  172
<212>  PRT
<213>  Homo sapiens

<400>  9508

Met Pro Lys Lys Leu Gly Pro Lys Ser Gln Arg Gln Arg Gly Ala Val 
1               5                   10                  15


Ala Pro Leu Thr Gln Val Gln Gln Ala Ala Cys Ser Pro Thr Tyr Lys 
            20                  25                  30


Gln Ala Lys Arg Asn Ala Arg Ser Tyr Gln Gly Arg Arg Arg Arg Arg 
        35                  40                  45


Arg Cys Ser Gln Asn Thr Thr Ser Arg Val Pro Ser Gln Leu Gln Ala 
    50                  55                  60


Val Asp Ser Ser Ser Ala Ser Cys Arg Thr Tyr Lys Asn Ser Glu Glu 
65                  70                  75                  80


Leu Arg Ser Arg Ile Val Ser Gly Ile Ile Thr Pro Ile His Glu Gln 
                85                  90                  95


Trp Glu Lys Ala Asn Val Ser Ser Pro His Arg Glu Phe Pro Pro Ala 
            100                 105                 110


Thr Ala Arg Glu Val Asp Pro Leu Arg Ile Pro Pro Leu Ala Ala Asp 
        115                 120                 125


Ser Ser Gln Arg Glu Ile Ser Val Ser Leu Ser Pro Ser Ala Pro Pro 
    130                 135                 140


Leu Ser Pro Pro Ala Pro Leu His Phe Pro Arg Glu Thr Pro Ala Thr 
145                 150                 155                 160


Phe Ser Asn Ile Tyr Pro Arg Pro Asp Ala Val Leu 
                165                 170


<210>  9509
<211>  799
<212>  DNA
<213>  Homo sapiens

<400>  9509
agttgtttca gaagaaatga gtttggcttg gattgctcca agaacaaaga aatgaacttg     60

gcttggattg ctccaaatac tggtttgaac acagtacagc agtggagcag aaacagagga    120

gatgacacca tggggtgtga tcccctgggc ccgtttgttg tcgggggaga agacttagac    180

ccttttgggc ctcggagagg tggcatgatt gtggatcccc tgagatctgg cttcccaaga    240

gcacttattg acccttcctc aggcctcccg aaccgacttc ctccaggcgc tgtgccccca    300

ggagctcgct ttgacccctt tggacccatt gggaccagcc cacccggacc taacccagac    360

catctccccc cgccgggcta cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc    420

ccaggcttcc ctccattctc ctggagctgc caccgctgtc cccatcagca accatgttct    480

tgcaggctgg gggcaaggga ttctgctcat gtgtttgcag accggctggg atagcctccc    540

caccccttat cagagccaag acacctgctg cagctctcca cctagctgca gatagctccc    600

aaagagaaat cagtgtgtct ctttcaccat cagctcctcc cctttcacca ccagctcctc    660

tccacttccc aagggagact ccggcaacct tcagcaacat atatcctcga ccagatgcag    720

tgctataaga acagaacgca ttttggatgt tattattaag aaccaaatgt caatacagaa    780

ttcatgttgc cggtttccc                                                 799


<210>  9510
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  9510

Met Asn Leu Ala Trp Ile Ala Pro Asn Thr Gly Leu Asn Thr Val Gln 
1               5                   10                  15


Gln Trp Ser Arg Asn Arg Gly Asp Asp Thr Met Gly Cys Asp Pro Leu 
            20                  25                  30


Gly Pro Phe Val Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg 
        35                  40                  45


Arg Gly Gly Met Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala 
    50                  55                  60


Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala 
65                  70                  75                  80


Val Pro Pro Gly Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser 
                85                  90                  95


Pro Pro Gly Pro Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp 
            100                 105                 110


Met Tyr Leu 
        115


<210>  9511
<211>  2647
<212>  DNA
<213>  Homo sapiens

<400>  9511
agttgtttca gaagaaatga gtttggcttg gattgctcca agaacaaaga aatgaacttg     60

gcttggattg ctccaaatac tggtttgaac acagtacagc agtggagcag aaacagagga    120

gatgacacca tggggtgtga tcccctgggc ccgtttgttg tcgggggaga agacttagac    180

ccttttgggc ctcggagagg tggcatgatt gtggatcccc tgagatctgg cttcccaaga    240

gcacttattg acccttcctc aggcctcccg aaccgacttc ctccaggcgc tgtgccccca    300

ggagctcgct ttgacccctt tggacccatt gggaccagcc cacccggacc taacccagac    360

catctccccc cgccgggcta cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc    420

ccaggcttcc ctccattctc ctggagctgc caccgctgtc cccatcagca accatgttct    480

tgcaggctgg gggcaaggga ttctgctcat gtgtttgcag accggctggg atagcctccc    540

caccccttat cagagccaag acacctgctg cagctctcca cctagctgca gatagctccc    600

aaagagaaat cagtgtgtct ctttcaccat cagctcctcc cctttcacca ccagctcctc    660

tccacttccc aagggagact ccggcaacct tcagcaacat atatcctcga ccagatgcag    720

tgctataaga acagaacgca ttttggatgt tattattaag aaccaaatgt caatacagaa    780

ttcatgttgc cggtttccca cttttctttt tacattaatg catagctgct tccatttatg    840

agactttaga gtttgagttt ctgtagggct gaatgactct ttttcctgcc cagggcccat    900

tcttgcttct caggcacctt ccgtttatta attgccattg ctcctgacat cactaagatg    960

ggtccccttc tggctgcatg aatggaaatg agtgactgga aatcccatag gccacaagaa   1020

tgactttcac aagggcagga acattgtgga aagactgcat cattctgatg aggcaaaatc   1080

ctccagctat tcctgtctgg gccagttttg taggtccatc tgtgcatggg cagcagtagt   1140

caaaaagcca aggaaaaaac agagcagacc tgaaggctaa tcttattttt gccactaact   1200

tagtgaatga ccctaagcaa gttccttctc ctcttagggc cttgtgccaa gcctatgaaa   1260

ttggaggtgg ctttcctgct ctaaagcatt ttgatgtctc attctgtgtt tggtaacccc   1320

tataaactgg ggcagaggaa aagaatgatg gttcaaggcc atacttccct tgaaccttgt   1380

gtggttcttg cctaactctg tggtttttgg accccatggg gcccagacag agcacaggag   1440

catgggctgc ctctgagtgt ggtgttgaac ttcgggagga gcagggagcc ctgcaccttg   1500

tgtcctggcc cacctgacct ttggtgttct ccggatcctt ttcagcccga ggcctgacag   1560

acgcgggcag tgatgagccc tgttctggag tggaaagagc acgatagagc accaggctaa   1620

gaggcacgag atcaaggcgg tagtcacttc cgctctgcag ctagcatttc aaccatatgt   1680

ggatcctttc atttctcagc tccctggatt ccttccccta aattaggacc tattatttac   1740

ctgtaggtaa gcaagctact gtagctcttc tgaggtatct gccaggctgt tttctgtagc   1800

ctcagattgc ctatctgctt agcctgagaa caggtagatg aaaactaaac tgatgcctag   1860

gcccagggtc agtctcagat ggaagctggg cctgggtggg gaggctagca tgcgtggctc   1920

cctgggtatt tctgtcagtc cccatggcaa gcagtgattt agtaaaacac cccagagtca   1980

gggaagccaa ccaccttgaa acctttagaa catctctgct ttggagaaag acccagagat   2040

caggcagagg tgcagattca atcattactc ataacctttg agagatggca aatgggagga   2100

gtgttagtct ttgttttgga attggaccat tcttgcaacc aaaaggactt agagcagttt   2160

gctcataaag acatccttta ttataaaagg aagtatttaa aggatgatag agaccatcag   2220

atagaagcag ggaaggtaga taacttttag gaccttgatg tgaggaaaag ataaaattta   2280

aacaataaat ttgccactta gattttctag cagcaaagtc cgaaaagata gttatataca   2340

aaattctgtt ttctgaaaac aaaattgtga ttcaccttca gaattggcca ttttttttgt   2400

gagtttcctt gcatcaagga cactgagaaa cacagtcatt gtcttaggtg ttctatggga   2460

ggaagtgaat agagccttta ggaacttcct ggtcaagctt atggtgctta ttttgatctg   2520

ggccacttcc ctccttccag tcatgagtaa tcatcaagga gcaagttgga gtgtttcagg   2580

tgtatatttt gtagaaccca aaagattgga gccttaacaa taaacatcag cactaagtga   2640

cctgttc                                                             2647


<210>  9512
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  9512

Met Asn Leu Ala Trp Ile Ala Pro Asn Thr Gly Leu Asn Thr Val Gln 
1               5                   10                  15


Gln Trp Ser Arg Asn Arg Gly Asp Asp Thr Met Gly Cys Asp Pro Leu 
            20                  25                  30


Gly Pro Phe Val Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg 
        35                  40                  45


Arg Gly Gly Met Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala 
    50                  55                  60


Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala 
65                  70                  75                  80


Val Pro Pro Gly Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser 
                85                  90                  95


Pro Pro Gly Pro Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp 
            100                 105                 110


Met Tyr Leu 
        115


<210>  9513
<211>  4313
<212>  DNA
<213>  Homo sapiens

<400>  9513
agttgtttca gaagaaatga gtttggcttg gattgctcca agaacaaaga aatgaacttg     60

gcttggattg ctccaaatac tggtttgaac acagtacagc agtggagcag aaacagagga    120

gatgacacca tggggtgtga tcccctgggc ccgtttgttg tcgggggaga agacttagac    180

ccttttgggc ctcggagagg tggcatgatt gtggatcccc tgagatctgg cttcccaaga    240

gcacttattg acccttcctc aggcctcccg aaccgacttc ctccaggcgc tgtgccccca    300

ggagctcgct ttgacccctt tggacccatt gggaccagcc cacccggacc taacccagac    360

catctccccc cgccgggcta cgatgacatg tacctgtgaa ggcctcaaga atgtaacatc    420

ccaggcttcc ctccattctc ctggagctgc caccgctgtc cccatcagca accatgttct    480

tgcaggctgg gggcaaggga ttctgctcat gtgtttgcag accggctggg atagcctccc    540

caccccttat cagagccaag acacctgctg cagctctcca cctagctgca gatagctccc    600

aaagagaaat cagtgtgtct ctttcaccat cagctcctcc cctttcacca ccagctcctc    660

tccacttccc aagggagact ccggcaacct tcagcaacat atatcctcga ccagatgcag    720

tgctataaga acagaacgca ttttggatgt tattattaag aaccaaatgt caatacagaa    780

ttcatgttgc cggtttccca cttttctttt tacattaatg catagctgct tccatttatg    840

agactttaga gtttgagttt ctgtagggct gaatgactct ttttcctgcc cagggcccat    900

tcttgcttct caggcacctt ccgtttatta attgccattg ctcctgacat cactaagatg    960

ggtccccttc tggctgcatg aatggaaatg agtgactgga aatcccatag gccacaagaa   1020

tgactttcac aagggcagga acattgtgga aagactgcat cattctgatg aggcaaaatc   1080

ctccagctat tcctgtctgg gccagttttg taggtccatc tgtgcatggg cagcagtagt   1140

caaaaagcca aggaaaaaac agagcagacc tgaaggctaa tcttattttt gccactaact   1200

tagtgaatga ccctaagcaa gttccttctc ctcttagggc cttgtgccaa gcctatgaaa   1260

ttggaggtgg ctttcctgct ctaaagcatt ttgatgtctc attctgtgtt tggtaacccc   1320

tataaactgg ggcagaggaa aagaatgatg gttcaaggcc atacttccct tgaaccttgt   1380

gtggttcttg cctaactctg tggtttttgg accccatggg gcccagacag agcacaggag   1440

catgggctgc ctctgagtgt ggtgttgaac ttcgggagga gcagggagcc ctgcaccttg   1500

tgtcctggcc cacctgacct ttggtgttct ccggatcctt ttcagcccga ggcctgacag   1560

acgcgggcag tgatgagccc tgttctggag tggaaagagc acgatagagc accaggctaa   1620

gaggcacgag atcaaggcgg tagtcacttc cgctctgcag ctagcatttc aaccatatgt   1680

ggatcctttc atttctcagc tccctggatt ccttccccta aattaggacc tattatttac   1740

ctgtaggtaa gcaagctact gtagctcttc tgaggtatct gccaggctgt tttctgtagc   1800

ctcagattgc ctatctgctt agcctgagaa caggtagatg aaaactaaac tgatgcctag   1860

gcccagggtc agtctcagat ggaagctggg cctgggtggg gaggctagca tgcgtggctc   1920

cctgggtatt tctgtcagtc cccatggcaa gcagtgattt agtaaaacac cccagagtca   1980

gggaagccaa ccaccttgaa acctttagaa catctctgct ttggagaaag acccagagat   2040

caggcagagg tgcagattca atcattactc ataacctttg agagatggca aatgggagga   2100

gtgttagtct ttgttttgga attggaccat tcttgcaacc aaaaggactt agagcagttt   2160

gctcataaag acatccttta ttataaaagg aagtatttaa aggatgatag agaccatcag   2220

atagaagcag ggaaggtaga taacttttag gaccttgatg tgaggaaaag ataaaattta   2280

aacaataaat ttgccactta gattttctag cagcaaagtc cgaaaagata gttatataca   2340

aaattctgtt ttctgaaaac aaaattgtga ttcaccttca gaattggcca ttttttttgt   2400

gagtttcctt gcatcaagga cactgagaaa cacagtcatt gtcttaggtg ttctatggga   2460

ggaagtgaat agagccttta ggaacttcct ggtcaagctt atggtgctta ttttgatctg   2520

ggccacttcc ctccttccag tcatgagtaa tcatcaagga gcaagttgga gtgtttcagg   2580

tgtatatttt gtagaaccca aaagattgga gccttaacaa taaacatcag cactaagtga   2640

cctgttcctc cttttttaaa tagcagcttt attgagatat aatttacata cccataattt   2700

acatacctgt ttaaagtata caattcagtg gatttagtat gttcacagtg ttgcacatcc   2760

accaccattt ctaattcctg aacattttca ccacctcaaa aagaaaccac acacccattg   2820

gcatgactcc ccattccctt gctcccagcc ccaggcaacc actaacatct gtctctaaag   2880

attttttttt tttttctgga cagttctcat aagtggaatc actcagtatt atggcctttt   2940

gtgtctggct tctttcattt catgtgatgt tttcaagatt cattcatgct gtagcatgta   3000

tccatggtat ggatatatca cattttgctt atccttttat cagttgatgg acagttgggt   3060

tgtttctaca aaaaggctat tatgagtaat gcagccaaga acatttgtgt accagttttt   3120

gagttttcag ttgtttgagt ttcagatgtt ttcagttcat ttgggtatat accaaggagt   3180

ggaattgctg gttcacatgg tagctctata ttctactttg tgaggaattg tcagactgtt   3240

ttccacggaa gctgcaccat tttacatttc cactggtaat ttatgagggt tccagtttcc   3300

ccacatcttc accaactctt gttatttttc atgcttatgg ccatcctagt tagcgtgaag   3360

tagcatctca ttgtggtctt ctcttccatt ttttaaaaaa gaattttgac ctacaccaag   3420

caaggcagag accagagtca gtcccccttg gggagcaatc tgtggttttg ataatcacca   3480

ccttgggatg aacatggctg gtgagctgca gagcagttga tttgactttt ggggatggtt   3540

ctaggctgga tgtgatacag ggcaggtttt gtctctagag aaagttctca tgaccttcag   3600

gtctaatgag attcagatca tcactttggt ttggtttgaa atttctttgt ttatccagtg   3660

aattacaagt agaataaaga tctggttcta aattgtcttt tggtggtgaa gtgccataga   3720

ccatttcgga ccatttctat gatgtaccag cagcccccac atcacacctc ctcttccttg   3780

gcttgtctct tccccaattc ttagagttag cagtgtttct tactgcattc atctcctcag   3840

tcataagtgt ctgtcaacct ccgttgtgaa gtcatgagtc tcttgagact gaaactccaa   3900

gaatgtattg tgctcacagt ggcgatggtg ttcctgtgct ggatggtcag tggttgttga   3960

catgtagtta gaaaataggt agcaagttcc acgcagcctc actctttgga acctagtttc   4020

tcctatggcc tccctttcta ctgttgttaa taacattcta ttaatgatcc atgcctctct   4080

tcacaggagg aatattagaa tctatggagc agttagtatt ctttgtcacc taaatttgtc   4140

tacttctgta catttccaat aaggcaccac cagggcaagg gaagattccc cacatgtata   4200

tccccagctg tttctgtcat aaaacttgca tgtgtataaa ccactattga ctttttgcac   4260

caaaggagat attcaaggac agacatccaa gtccccagcc ctttattgcc ctt          4313


<210>  9514
<211>  115
<212>  PRT
<213>  Homo sapiens

<400>  9514

Met Asn Leu Ala Trp Ile Ala Pro Asn Thr Gly Leu Asn Thr Val Gln 
1               5                   10                  15


Gln Trp Ser Arg Asn Arg Gly Asp Asp Thr Met Gly Cys Asp Pro Leu 
            20                  25                  30


Gly Pro Phe Val Val Gly Gly Glu Asp Leu Asp Pro Phe Gly Pro Arg 
        35                  40                  45


Arg Gly Gly Met Ile Val Asp Pro Leu Arg Ser Gly Phe Pro Arg Ala 
    50                  55                  60


Leu Ile Asp Pro Ser Ser Gly Leu Pro Asn Arg Leu Pro Pro Gly Ala 
65                  70                  75                  80


Val Pro Pro Gly Ala Arg Phe Asp Pro Phe Gly Pro Ile Gly Thr Ser 
                85                  90                  95


Pro Pro Gly Pro Asn Pro Asp His Leu Pro Pro Pro Gly Tyr Asp Asp 
            100                 105                 110


Met Tyr Leu 
        115


<210>  9515
<211>  2345
<212>  DNA
<213>  Homo sapiens

<400>  9515
tccctgagaa gaggagctct tgggccaatc acctagtttc tgcctgtgtt acagtgaaga     60

gaagctgctt aagagaagat gaagcccttg tctctgttaa tagagatatt gataattctt    120

ggggtcacaa ttaaaactat caaagcagag gaacataata aaagacaaaa ggaaagaaat    180

gtcaccacac aggtatcagt gaacgaaatc aaacaatatt tatcacacat attggaacaa    240

agaacatcta gtaatgtaat caataaaaga gaaaatctcc tggagaaaaa gaagaatcaa    300

cgtaaaataa gaataaaagg aattcaaaat aaagatatct tgaagagaaa taagaatcat    360

ttacaaaagc aagcagagaa aaattttaca gatgaaggag accagctatt taagatgggc    420

atcaaggttc tccagcagtc taaaagccaa aaacaaaaag aagagattct aatgcctacc    480

tggatgtttc tctgtctgag gtccttcttg cctggactac tctgctccag cttctgccca    540

agagcagctt attttagcct cagcatggat gggctgtaca taaagagcct acctactttt    600

tgccaaagca gctgacatgg gaaacttgaa agctatggag aaaatggctg acgctttgct    660

atttggaaat tttggcgtgc aaaatataac agcagctatc caattatatg agtccttggc    720

taaagaagga tcatgtaaag cccaaaacgc attaggattt ttgtcttctt atggaatagg    780

aatggaatat gatcaagcta aggcactgat atattacacc tttggaagtg ctggaggaaa    840

catgatgtcc cagatgattt tggggtacag atatttgtcg ggaatcaatg ttctacagaa    900

ttgtgaagtt gccctaagtt attacaagaa agtggcagat tatattgctg acacatttga    960

aaaaagtgaa ggtgttccag tggaaaaagt gagactaacg gaaagacctg aaaatctgag   1020

ttctaacagt gagattttgg attgggacat ataccaatac tataaatttt tggcagaaag   1080

aggagatgtt cagatacaag tctctcttgg acaattacat ctaattggca ggaaaggtct   1140

agatcaggat tactacaaag cattacacta cttcttaaag gcagcaaagg ccgggagtgc   1200

aaatgccatg gcatttatag gaaagatgta tttagagggg aatgctgccg tgccgcaaaa   1260

taacgctact gccttcaagt acttttccat ggcagccagt aagggcaatg caatcggcct   1320

tcatgggctt ggtcttcttt actttcatgg aaaaggagtt cccctgaatt atgccgaagc   1380

acttaaatac tttcagaaag ctgcggaaaa agggtggccc gacgcacagt tccagttagg   1440

cttcatgtac tactctggct ctggaatatg gaaggattat aaacttgcct tcaaatattt   1500

ttacctggca tctcagagtg ggcagcccct tgccatttat tatctggcca agatgtatgc   1560

aacaggaaca ggagtagtaa gatcatgcag aactgctgtg gagctttata aaggtgtctg   1620

tgaactaggc cactgggctg agaaattcct gacagcttac tttgcctata aggatggtga   1680

tatagattct tctcttgttc agtatgcact gcttgcagaa atggggtatg aagtagctca   1740

aagcaattca gcattcattt tggaatctaa aaaggctaac attcttgaaa aagagaagat   1800

gtatccaatg gcgcttctcc tatggaatcg agctgccatt caaggcaatg catttgctag   1860

agtaaaaatt ggagattacc attactatgg ctatgggact aagaaagact atcaaacagc   1920

agccacacac tacagcattg cagccaacaa ataccacaac gcgcaagcca tgttcaatct   1980

ggcttatatg tatgaacacg gcttaggcat cacaaaggac attcacttgg ccagaagatt   2040

gtacgacatg gctgctcaaa cgagtccaga tgcccacata cctgtgctct ttgccgtcat   2100

gaaactggaa actacgcatt tgctccggga tatcctgttt tttaatttca caacgagatg   2160

gaactggctg aaactggaca acaccattgg accacactgg gacttatttg tgattggcct   2220

cattgttcct gggctgattt tgttgcttag aaatcaccat gggtaggatg cggatcacag   2280

gaaaacctgc tcacgggaat cagttcactc caaggtatcc ccactaaata aacagtttcc   2340

catcc                                                               2345


<210>  9516
<211>  549
<212>  PRT
<213>  Homo sapiens

<400>  9516

Met Gly Asn Leu Lys Ala Met Glu Lys Met Ala Asp Ala Leu Leu Phe 
1               5                   10                  15


Gly Asn Phe Gly Val Gln Asn Ile Thr Ala Ala Ile Gln Leu Tyr Glu 
            20                  25                  30


Ser Leu Ala Lys Glu Gly Ser Cys Lys Ala Gln Asn Ala Leu Gly Phe 
        35                  40                  45


Leu Ser Ser Tyr Gly Ile Gly Met Glu Tyr Asp Gln Ala Lys Ala Leu 
    50                  55                  60


Ile Tyr Tyr Thr Phe Gly Ser Ala Gly Gly Asn Met Met Ser Gln Met 
65                  70                  75                  80


Ile Leu Gly Tyr Arg Tyr Leu Ser Gly Ile Asn Val Leu Gln Asn Cys 
                85                  90                  95


Glu Val Ala Leu Ser Tyr Tyr Lys Lys Val Ala Asp Tyr Ile Ala Asp 
            100                 105                 110


Thr Phe Glu Lys Ser Glu Gly Val Pro Val Glu Lys Val Arg Leu Thr 
        115                 120                 125


Glu Arg Pro Glu Asn Leu Ser Ser Asn Ser Glu Ile Leu Asp Trp Asp 
    130                 135                 140


Ile Tyr Gln Tyr Tyr Lys Phe Leu Ala Glu Arg Gly Asp Val Gln Ile 
145                 150                 155                 160


Gln Val Ser Leu Gly Gln Leu His Leu Ile Gly Arg Lys Gly Leu Asp 
                165                 170                 175


Gln Asp Tyr Tyr Lys Ala Leu His Tyr Phe Leu Lys Ala Ala Lys Ala 
            180                 185                 190


Gly Ser Ala Asn Ala Met Ala Phe Ile Gly Lys Met Tyr Leu Glu Gly 
        195                 200                 205


Asn Ala Ala Val Pro Gln Asn Asn Ala Thr Ala Phe Lys Tyr Phe Ser 
    210                 215                 220


Met Ala Ala Ser Lys Gly Asn Ala Ile Gly Leu His Gly Leu Gly Leu 
225                 230                 235                 240


Leu Tyr Phe His Gly Lys Gly Val Pro Leu Asn Tyr Ala Glu Ala Leu 
                245                 250                 255


Lys Tyr Phe Gln Lys Ala Ala Glu Lys Gly Trp Pro Asp Ala Gln Phe 
            260                 265                 270


Gln Leu Gly Phe Met Tyr Tyr Ser Gly Ser Gly Ile Trp Lys Asp Tyr 
        275                 280                 285


Lys Leu Ala Phe Lys Tyr Phe Tyr Leu Ala Ser Gln Ser Gly Gln Pro 
    290                 295                 300


Leu Ala Ile Tyr Tyr Leu Ala Lys Met Tyr Ala Thr Gly Thr Gly Val 
305                 310                 315                 320


Val Arg Ser Cys Arg Thr Ala Val Glu Leu Tyr Lys Gly Val Cys Glu 
                325                 330                 335


Leu Gly His Trp Ala Glu Lys Phe Leu Thr Ala Tyr Phe Ala Tyr Lys 
            340                 345                 350


Asp Gly Asp Ile Asp Ser Ser Leu Val Gln Tyr Ala Leu Leu Ala Glu 
        355                 360                 365


Met Gly Tyr Glu Val Ala Gln Ser Asn Ser Ala Phe Ile Leu Glu Ser 
    370                 375                 380


Lys Lys Ala Asn Ile Leu Glu Lys Glu Lys Met Tyr Pro Met Ala Leu 
385                 390                 395                 400


Leu Leu Trp Asn Arg Ala Ala Ile Gln Gly Asn Ala Phe Ala Arg Val 
                405                 410                 415


Lys Ile Gly Asp Tyr His Tyr Tyr Gly Tyr Gly Thr Lys Lys Asp Tyr 
            420                 425                 430


Gln Thr Ala Ala Thr His Tyr Ser Ile Ala Ala Asn Lys Tyr His Asn 
        435                 440                 445


Ala Gln Ala Met Phe Asn Leu Ala Tyr Met Tyr Glu His Gly Leu Gly 
    450                 455                 460


Ile Thr Lys Asp Ile His Leu Ala Arg Arg Leu Tyr Asp Met Ala Ala 
465                 470                 475                 480


Gln Thr Ser Pro Asp Ala His Ile Pro Val Leu Phe Ala Val Met Lys 
                485                 490                 495


Leu Glu Thr Thr His Leu Leu Arg Asp Ile Leu Phe Phe Asn Phe Thr 
            500                 505                 510


Thr Arg Trp Asn Trp Leu Lys Leu Asp Asn Thr Ile Gly Pro His Trp 
        515                 520                 525


Asp Leu Phe Val Ile Gly Leu Ile Val Pro Gly Leu Ile Leu Leu Leu 
    530                 535                 540


Arg Asn His His Gly 
545


<210>  9517
<211>  2117
<212>  DNA
<213>  Homo sapiens

<400>  9517
ggtggaccgc gcttaccgct ggcctcttgg aagacttgag ggcgtggcct gtagagccag     60

gtgcgccaag tgacaggcga gctagcggaa agccgcctca gggacttgga ggatgtagaa    120

gtgggaggag accgagggtc aacacgaatt gtccgtgctc actccaactg ccctgttgag    180

gaggattttc accagctatc aaagcagagg aacataataa aagacaaaag gaaagaaatg    240

tcaccacaca ggtatcagtg aacgaaatca aacaatattt atcacacata ttggaacaaa    300

gaacatctag taatgtaatc aataaaagag aaaatctcct ggagaaaaag aagaatcaac    360

gtaaaataag aataaaagga attcaaaata aagatatctt gaagagaaat aagaatcatt    420

tacaaaagca agcagagaaa aattttacag atgaaggaga ccagctattt aagatgggca    480

tcaaggttct ccagcagtct aaaagccaaa aacaaaaaga agaagcctac ctactttttg    540

ccaaagcagc tgacatggga aacttgaaag ctatggagaa aatggctgac gctttgctat    600

ttggaaattt tggcgtgcaa aatataacag cagctatcca attatatgag tccttggcta    660

aagaaggatc atgtaaagcc caaaacgcat taggattttt gtcttcttat ggaataggaa    720

tggaatatga tcaagctaag gcactgatat attacacctt tggaagtgct ggaggaaaca    780

tgatgtccca gatgattttg gggtacagat atttgtcggg aatcaatgtt ctacagaatt    840

gtgaagttgc cctaagttat tacaagaaag tggcagatta tattgctgac acatttgaaa    900

aaagtgaagg tgttccagtg gaaaaagtga gactaacgga aagacctgaa aatctgagtt    960

ctaacagtga gattttggat tgggacatat accaatacta taaatttttg gcagaaagag   1020

gagatgttca gatacaagtc tctcttggac aattacatct aattggcagg aaaggtctag   1080

atcaggatta ctacaaagca ttacactact tcttaaaggc agcaaaggcc gggagtgcaa   1140

atgccatggc atttatagga aagatgtatt tagaggggaa tgctgccgtg ccgcaaaata   1200

acgctactgc cttcaagtac ttttccatgg cagccagtaa gggcaatgca atcggccttc   1260

atgggcttgg tcttctttac tttcatggaa aaggagttcc cctgaattat gccgaagcac   1320

ttaaatactt tcagaaagct gcggaaaaag ggtggcccga cgcacagttc cagttaggct   1380

tcatgtacta ctctggctct ggaatatgga aggattataa acttgccttc aaatattttt   1440

acctggcatc tcagagtggg cagccccttg ccatttatta tctggccaag atgtatgcaa   1500

caggaacagg agtagtaaga tcatgcagaa ctgctgtgga gaaaaggcta acattcttga   1560

aaaagagaag atgtatccaa tggcgcttct cctatggaat cgagctgcca ttcaaggcaa   1620

tgcatttgct agagtaaaaa ttggagatta ccattactat ggctatggga ctaagaaaga   1680

ctatcaaaca gcagccacac actacagcat tgcagccaac aaataccaca acgcgcaagc   1740

catgttcaat ctggcttata tgtatgaaca cggcttaggc atcacaaagg acattcactt   1800

ggccagaaga ttgtacgaca tggctgctca aacgagtcca gatgcccaca tacctgtgct   1860

ctttgccgtc atgaaactgg aaactacgca tttgctccgg gatatcctgt tttttaattt   1920

cacaacgaga tggaactggc tgaaactgga caacaccatt ggaccacact gggacttatt   1980

tgtgattggc ctcattgttc ctgggctgat tttgttgctt agaaatcacc atgggtagga   2040

tgcggatcac aggaaaacct gctcacggga atcagttcac tccaaggtat ccccactaaa   2100

taaacagttt cccatcc                                                  2117


<210>  9518
<211>  387
<212>  PRT
<213>  Homo sapiens

<400>  9518

Met Gly Ile Lys Val Leu Gln Gln Ser Lys Ser Gln Lys Gln Lys Glu 
1               5                   10                  15


Glu Ala Tyr Leu Leu Phe Ala Lys Ala Ala Asp Met Gly Asn Leu Lys 
            20                  25                  30


Ala Met Glu Lys Met Ala Asp Ala Leu Leu Phe Gly Asn Phe Gly Val 
        35                  40                  45


Gln Asn Ile Thr Ala Ala Ile Gln Leu Tyr Glu Ser Leu Ala Lys Glu 
    50                  55                  60


Gly Ser Cys Lys Ala Gln Asn Ala Leu Gly Phe Leu Ser Ser Tyr Gly 
65                  70                  75                  80


Ile Gly Met Glu Tyr Asp Gln Ala Lys Ala Leu Ile Tyr Tyr Thr Phe 
                85                  90                  95


Gly Ser Ala Gly Gly Asn Met Met Ser Gln Met Ile Leu Gly Tyr Arg 
            100                 105                 110


Tyr Leu Ser Gly Ile Asn Val Leu Gln Asn Cys Glu Val Ala Leu Ser 
        115                 120                 125


Tyr Tyr Lys Lys Val Ala Asp Tyr Ile Ala Asp Thr Phe Glu Lys Ser 
    130                 135                 140


Glu Gly Val Pro Val Glu Lys Val Arg Leu Thr Glu Arg Pro Glu Asn 
145                 150                 155                 160


Leu Ser Ser Asn Ser Glu Ile Leu Asp Trp Asp Ile Tyr Gln Tyr Tyr 
                165                 170                 175


Lys Phe Leu Ala Glu Arg Gly Asp Val Gln Ile Gln Val Ser Leu Gly 
            180                 185                 190


Gln Leu His Leu Ile Gly Arg Lys Gly Leu Asp Gln Asp Tyr Tyr Lys 
        195                 200                 205


Ala Leu His Tyr Phe Leu Lys Ala Ala Lys Ala Gly Ser Ala Asn Ala 
    210                 215                 220


Met Ala Phe Ile Gly Lys Met Tyr Leu Glu Gly Asn Ala Ala Val Pro 
225                 230                 235                 240


Gln Asn Asn Ala Thr Ala Phe Lys Tyr Phe Ser Met Ala Ala Ser Lys 
                245                 250                 255


Gly Asn Ala Ile Gly Leu His Gly Leu Gly Leu Leu Tyr Phe His Gly 
            260                 265                 270


Lys Gly Val Pro Leu Asn Tyr Ala Glu Ala Leu Lys Tyr Phe Gln Lys 
        275                 280                 285


Ala Ala Glu Lys Gly Trp Pro Asp Ala Gln Phe Gln Leu Gly Phe Met 
    290                 295                 300


Tyr Tyr Ser Gly Ser Gly Ile Trp Lys Asp Tyr Lys Leu Ala Phe Lys 
305                 310                 315                 320


Tyr Phe Tyr Leu Ala Ser Gln Ser Gly Gln Pro Leu Ala Ile Tyr Tyr 
                325                 330                 335


Leu Ala Lys Met Tyr Ala Thr Gly Thr Gly Val Val Arg Ser Cys Arg 
            340                 345                 350


Thr Ala Val Glu Lys Arg Leu Thr Phe Leu Lys Lys Arg Arg Cys Ile 
        355                 360                 365


Gln Trp Arg Phe Ser Tyr Gly Ile Glu Leu Pro Phe Lys Ala Met His 
    370                 375                 380


Leu Leu Glu 
385


<210>  9519
<211>  764
<212>  DNA
<213>  Homo sapiens

<400>  9519
tgttacagtg aagagaagct gcttaagaga agatgaagcc cttgtctctg ttaatagaga     60

tattgataat tcttggggtc acaattaaaa ctatcaaagc agaggaacat aataaaagac    120

aaaaggaaag aaatgtcacc acacaggtat cagtgaacga aatcaaacaa tatttatcac    180

acatattgga acaaagaaca tctagtaatg taatcaataa aagagaaaat ctcctggaga    240

aaaagaagaa tcaacgtaaa ataagaataa aaggaattca aaataaagat atcttgaaga    300

gaaataagaa tcatttacaa aagcaagcag agaaaaattt tacagatgaa ggagaccagc    360

tatttaagat gggcatcaag gttctccagc agtctaaaag ccaaaaacaa aaagaagaag    420

cctacctact ttttgccaaa gcagctgaca tgggaaactt gaaagctatg gagaaaatgg    480

ctgacgcttt gctatttgga aattttggcg tgcaaaatat aacagcagct atccaattat    540

atgagtcctt ggctaaagaa ggatcatgta aagcccaaaa cgcattagga tttttgtctt    600

cttatggaat aggaatggaa tatgatcaag ctaaggcact gatatattac acctttggaa    660

gtgctggagg aaacatgatg tcccagatga ttttggggta cagatatttg tcgggaatca    720

atgttctaca gaattgtgaa gttgccctaa gttattacaa gaaa                     764


<210>  9520
<211>  243
<212>  PRT
<213>  Homo sapiens

<400>  9520

Met Lys Pro Leu Ser Leu Leu Ile Glu Ile Leu Ile Ile Leu Gly Val 
1               5                   10                  15


Thr Ile Lys Thr Ile Lys Ala Glu Glu His Asn Lys Arg Gln Lys Glu 
            20                  25                  30


Arg Asn Val Thr Thr Gln Val Ser Val Asn Glu Ile Lys Gln Tyr Leu 
        35                  40                  45


Ser His Ile Leu Glu Gln Arg Thr Ser Ser Asn Val Ile Asn Lys Arg 
    50                  55                  60


Glu Asn Leu Leu Glu Lys Lys Lys Asn Gln Arg Lys Ile Arg Ile Lys 
65                  70                  75                  80


Gly Ile Gln Asn Lys Asp Ile Leu Lys Arg Asn Lys Asn His Leu Gln 
                85                  90                  95


Lys Gln Ala Glu Lys Asn Phe Thr Asp Glu Gly Asp Gln Leu Phe Lys 
            100                 105                 110


Met Gly Ile Lys Val Leu Gln Gln Ser Lys Ser Gln Lys Gln Lys Glu 
        115                 120                 125


Glu Ala Tyr Leu Leu Phe Ala Lys Ala Ala Asp Met Gly Asn Leu Lys 
    130                 135                 140


Ala Met Glu Lys Met Ala Asp Ala Leu Leu Phe Gly Asn Phe Gly Val 
145                 150                 155                 160


Gln Asn Ile Thr Ala Ala Ile Gln Leu Tyr Glu Ser Leu Ala Lys Glu 
                165                 170                 175


Gly Ser Cys Lys Ala Gln Asn Ala Leu Gly Phe Leu Ser Ser Tyr Gly 
            180                 185                 190


Ile Gly Met Glu Tyr Asp Gln Ala Lys Ala Leu Ile Tyr Tyr Thr Phe 
        195                 200                 205


Gly Ser Ala Gly Gly Asn Met Met Ser Gln Met Ile Leu Gly Tyr Arg 
    210                 215                 220


Tyr Leu Ser Gly Ile Asn Val Leu Gln Asn Cys Glu Val Ala Leu Ser 
225                 230                 235                 240


Tyr Tyr Lys 



<210>  9521
<211>  711
<212>  DNA
<213>  Homo sapiens

<400>  9521
tacaaaagca agcagagaaa aattttacag atgaaggaga ccagctattt aagatgggca     60

tcaaggttct ccagcagtct aaaagccaaa aacaaaaaga agagattcta atgcctacct    120

ggatgtttct ctgtctgagg tccttcttgc ctggactact ctgctccagc ttctgcccaa    180

gagcagctta ttttagcctc agcatggatg ggctgtacat aaagagccta cctacttttt    240

gccaaagcag ctgacatggg aaacttgaaa gctatggaga aaatggctga cgctttgcta    300

tttggaaatt ttggcgtgca aaatataaca gcagctatcc aattatatga gtccttggct    360

aaagaaggat catgtaaagc ccaaaacgtg agttttgaag gaaaatgaaa ccttaaatag    420

ctccatcctg aaataactat agacagcatg tgaaaggagt tgagcaatag tattccagct    480

ctgctgcatg aacccagtct agggaggtta ccataatgca ctgaaacagt ggtgtcaggg    540

caggagtaca gcagaagcct ccgaaccccc aacagctaaa ttttatataa aatgtattca    600

cctatatgaa gaaatatgaa actgtctatt atcttagggt gacatgtttg catgattttt    660

acttttcaaa tattttataa gctaaatgta attccttttc tattttaata a             711


<210>  9522
<211>  66
<212>  PRT
<213>  Homo sapiens

<400>  9522

Met Gly Ile Lys Val Leu Gln Gln Ser Lys Ser Gln Lys Gln Lys Glu 
1               5                   10                  15


Glu Ile Leu Met Pro Thr Trp Met Phe Leu Cys Leu Arg Ser Phe Leu 
            20                  25                  30


Pro Gly Leu Leu Cys Ser Ser Phe Cys Pro Arg Ala Ala Tyr Phe Ser 
        35                  40                  45


Leu Ser Met Asp Gly Leu Tyr Ile Lys Ser Leu Pro Thr Phe Cys Gln 
    50                  55                  60


Ser Ser 
65


<210>  9523
<211>  535
<212>  DNA
<213>  Homo sapiens

<400>  9523
ctctgaaggc acttatcctc acggacaaca cgctcgtttt agggctcccc tagagttcca     60

ggtttcaaaa gtcacgctgc ggcagcgaag gaaggaaacc tagacaaggg gtaaacaccc    120

gatgctatca aagcagagga acataataaa agacaaaagg aaagaaatgt caccacacag    180

gtatcagtga acgaaatcaa acaatattta tcacacatat tggaacaaag aacatctagt    240

aatgtaatca ataaaagaga aaatctcctg gagaaaaaga agaatcaacg taaaataaga    300

ataaaaggaa ttcaaaataa agatatcttg aagagaaata agaatcattt acaaaagcaa    360

gcagagaaaa attttacaga tgaaggagac cagctattta agatgggcat caaggttctc    420

cagcagtcta aaagccaaaa acaaaaagaa gaagcctacc tactttttgc caaagcagct    480

gacatgggaa acttgaaagc tatggagaaa atggctgacg ctttgctatt tggaa         535


<210>  9524
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9524

Met Gly Ile Lys Val Leu Gln Gln Ser Lys Ser Gln Lys Gln Lys Glu 
1               5                   10                  15


Glu Ala Tyr Leu Leu Phe Ala Lys Ala Ala Asp Met Gly Asn Leu Lys 
            20                  25                  30


Ala Met Glu Lys Met Ala Asp Ala Leu Leu Phe 
        35                  40


<210>  9525
<211>  408
<212>  DNA
<213>  Homo sapiens

<400>  9525
taggtatcag tgaacgaaat caaacaatat ttatcacaca tattggaaca aagaacatct     60

agtaatgtaa tcaataaaag agaaaatctc ctggagaaaa agaagaatca acgtaaaata    120

agaataaaag gaattcaaaa taaagatatc ttgaagagaa ataagaatca ttggtgagaa    180

gaaaagaaca ggagaagaac tatgaaaaca gcagatgtga ggagcaagaa agatggtgat    240

tggctgcgct aaactgaaaa gttagtgaaa cttcaaagtt gggggattcc aactgatatt    300

tttaaatcag caatgtctaa ggtgaccatt aaaaattgtt tttgttccta ggataactca    360

tcttctcttc tgctctatga aatcttagat aaaatgtgta ttcctcat                 408


<210>  9526
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  9526

Val Ser Val Asn Glu Ile Lys Gln Tyr Leu Ser His Ile Leu Glu Gln 
1               5                   10                  15


Arg Thr Ser Ser Asn Val Ile Asn Lys Arg Glu Asn Leu Leu Glu Lys 
            20                  25                  30


Lys Lys Asn Gln Arg Lys Ile Arg Ile Lys Gly Ile Gln Asn Lys Asp 
        35                  40                  45


Ile Leu Lys Arg Asn Lys Asn His Trp 
    50                  55


<210>  9527
<211>  437
<212>  DNA
<213>  Homo sapiens

<400>  9527
gaacgaaatc aaacaatatt tatcacacat attggaacaa agaacatcta gtaatgtaat     60

caataaaaga gaaaatctcc tggagaaaaa gaagaatcaa cgtaaaataa gaataaaagg    120

aattcaaaat aaagatatct tgaagagaaa taagaatcat taagcctggt gtcagctgat    180

gccaagtctt caaggatgga aagacattgc cctacagaac tagggagagg aacgttgaca    240

ttttgttttt gaaagggtga gaagaaaaga acaggagaag aactatgaaa acagcagatg    300

tgaggagcaa gaaagatggt gattggctgc gctaaactga aaagttagtg aaacttcaaa    360

gttgggggat tccaactgat atttttaaat cagcaatgtc taaggtgacc attaaaaatt    420

gtttttgttc ctaggat                                                   437


<210>  9528
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  9528

Asn Glu Ile Lys Gln Tyr Leu Ser His Ile Leu Glu Gln Arg Thr Ser 
1               5                   10                  15


Ser Asn Val Ile Asn Lys Arg Glu Asn Leu Leu Glu Lys Lys Lys Asn 
            20                  25                  30


Gln Arg Lys Ile Arg Ile Lys Gly Ile Gln Asn Lys Asp Ile Leu Lys 
        35                  40                  45


Arg Asn Lys Asn His 
    50


<210>  9529
<211>  351
<212>  DNA
<213>  Homo sapiens

<400>  9529
ggtatcagtg aacgaaatca aacaatattt atcacacata ttggaacaaa gaacatctag     60

taatgtaatc aataaaagag aaaatctcct ggagaaaaag aagaatcaac gtaaaataag    120

aataaaagga attcaaaata aagatatctt gaagagaaat aagaatcatt ggtgagaaga    180

aaagaacagg agaagaacta tgaaaacagc agatgtgagg agcaagaaag atggtgattg    240

gctgcgctaa actgaaaagt tagtgaaact tcaaagttgg gggattccaa ctgatatttt    300

taaatcagca atgtctaagg tgaccattaa aaattgtttt tgttcctagg a             351


<210>  9530
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  9530

Val Ser Val Asn Glu Ile Lys Gln Tyr Leu Ser His Ile Leu Glu Gln 
1               5                   10                  15


Arg Thr Ser Ser Asn Val Ile Asn Lys Arg Glu Asn Leu Leu Glu Lys 
            20                  25                  30


Lys Lys Asn Gln Arg Lys Ile Arg Ile Lys Gly Ile Gln Asn Lys Asp 
        35                  40                  45


Ile Leu Lys Arg Asn Lys Asn His Trp 
    50                  55


<210>  9531
<211>  530
<212>  DNA
<213>  Homo sapiens

<400>  9531
aagagagaaa gtagagacat aatgattata gagttcttcc tggattgtgg cagtgttcag     60

gatcagactc tagctatcaa tagatcgttc attaattgtg ggtgtataga gaaccaggga    120

aggagttagt ggaagagaaa acagttattt tttaaaagct agtgctggcg ggccacagtg    180

gttcatacct acaatcccag cactttggga ggtccaggcg ggcagatcac gtgaggtcgg    240

gagtttgaga ccagcctgac caacatggag aaaccccgtc tctactaaaa atacaaaatt    300

agctgggcgt ggtggtgcat gcctgtaatc ccagctactc cagaggctga ggcgggagaa    360

tcgcttgaac ttgggaggca gagggttgca gtgagttgag atcgtgccat tgcactccag    420

cctgggcaac aagagcgaaa ctcctatctc tactaaaaat aaaaaaatta gccaggcaca    480

tgcctgtaat cccagctact tgggagcctg aggcaggaga atagcttgaa               530


<210>  9532
<211>  35
<212>  PRT
<213>  Homo sapiens

<400>  9532

Met Ile Ile Glu Phe Phe Leu Asp Cys Gly Ser Val Gln Asp Gln Thr 
1               5                   10                  15


Leu Ala Ile Asn Arg Ser Phe Ile Asn Cys Gly Cys Ile Glu Asn Gln 
            20                  25                  30


Gly Arg Ser 
        35


<210>  9533
<211>  1425
<212>  DNA
<213>  Homo sapiens

<400>  9533
gcgtgcgccc tggggcccaa gttggggcgc gccgtggcta gaacacggag agcggcgggc     60

agtgcagcca atgggaggcg gcgctgccta gcggctggta ggcggtgcct gcgcgggtgt    120

taggttagcg cgaggcgtga cctagttgac aggctctgag gtgctgctgt ggcggcgtcc    180

gcggggctga ggcgggtggg agccggagcc gagcgcgggc tgagggagga gggcggcgac    240

tggagagcgg cgagcggcga gcagcgcagg acgcagagcc tctttcactt tttccctgct    300

gagtgccccc tcccacccct cccactccac acacaccctg tttgcccgtg agcctgggga    360

acttgcagct taaagccagc cacccccacg gcaacatgta ccccagcaac aagaagaaaa    420

aggtgtggag agaggagaaa gaacgtttat tgaagatgac cttagaagag agacgcaaag    480

aatacctaag agactatatt cccctgaaca gcattctatc atggaaggag gagatgaagg    540

gcaagggcca aaatgatgga tgcatctctc atggttgaag aagtggtgga ggatggcatg    600

ggaaagagtg cctgaggatc cttgcctgga acaagttatg gaaagaaagt cttacagctt    660

gggctctagg aaaagagcct tttatcccac cttgtcttcc agtccatttt gaatcaagaa    720

agactcattg aagactcctt tgagaaaagt ctgttttgaa gaaggaaaaa gaaatactgt    780

ttgagagaag gcaaacagac aaaaagggtg atagaaatat gtatttttgt tgtatatgta    840

actctaagag accttcctag agtgaatgaa ggtagaaaac tgaaaaggga gtaaattaag    900

gaatgattga attttgtggg tcttgatgga aaaacgctgg tcttctttta atgtggaaaa    960

acagctagtg cttcagtcct aggaattatg tctctgctgt gggcagttgt cataaactct   1020

tctcacaatc cgagctgctc tttgtcctct gtgaatgaag gtacttttgc ttccatttca   1080

tccaaggatg aatgaaaatg tatagcatct gcccaaacct aaaaagtaca gtgtgtttat   1140

cacgagagct ttgtaaggta cttcacttcc actttaaaat tctttagtgc tcaaaaccaa   1200

ctattgtggg tttttgtcaa taaatactaa tttttcaaga tgaagtatgg tgatttctat   1260

tcatattgtg gtcaattttc tcaattttgt ttcccataga tagcgtgatg gaacttaaat   1320

tttatttttt acacttaaat aactgtgctt tttgtgatgc gtaatcatga ttttctcttt   1380

tccttgagat tttaacagac cttatattag tgcatatgtc aaaat                   1425


<210>  9534
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  9534

Met Tyr Pro Ser Asn Lys Lys Lys Lys Val Trp Arg Glu Glu Lys Glu 
1               5                   10                  15


Arg Leu Leu Lys Met Thr Leu Glu Glu Arg Arg Lys Glu Tyr Leu Arg 
            20                  25                  30


Asp Tyr Ile Pro Leu Asn Ser Ile Leu Ser Trp Lys Glu Glu Met Lys 
        35                  40                  45


Gly Lys Gly Gln Asn Asp Gly Cys Ile Ser His Gly 
    50                  55                  60


<210>  9535
<211>  4998
<212>  DNA
<213>  Homo sapiens

<400>  9535
gcgtgcgccc tggggcccaa gttggggcgc gccgtggcta gaacacggag agcggcgggc     60

agtgcagcca atgggaggcg gcgctgccta gcggctggta ggcggtgcct gcgcgggtgt    120

taggttagcg cgaggcgtga cctagttgac aggctctgag gtgctgctgt ggcggcgtcc    180

gcggggctga ggcgggtggg agccggagcc gagcgcgggc tgagggagga gggcggcgac    240

tggagagcgg cgagcggcga gcagcgcagg acgcagagcc tctttcactt tttccctgct    300

gagtgccccc tcccacccct cccactccac acacaccctg tttgcccgtg agcctgggga    360

acttgcagct taaagccagc cacccccacg gcaacatgta ccccagcaac aagaagaaaa    420

aggtgtggag agaggagaaa gaacgtttat tgaagatgac cttagaagag agacgcaaag    480

aatacctaag agactatatt cccctgaaca gcattctatc atggaaggag gagatgaagg    540

gcaagggcca aaatgatgaa gaaaatactc aggaaacatc ccaggtgaag aaaagtttga    600

ctgaaaaagt ttctctctat agaggtgaca tcacattgct agaggtagat gctatagtca    660

atgccgcaaa tgccagtctt cttggaggag gaggtgtgga tggctgtatt catagagcag    720

ccggcccctg tttgctagct gaatgtcgta acctgaatgg ctgtgatact ggacatgcaa    780

aaatcacatg tggctatgac cttcctgcaa aatatgtcat ccatactgta gggccaatag    840

ccaggggcca tattaatggt tcccacaagg aagaccttgc aaattgctat aaatcatctc    900

tgaagctcgt gaaagaaaat aacatccgat cagttgcatt tccctgcatc tcaacaggca    960

tttatggctt tcccaacgag cctgctgcag tcattgccct caacaccatt aaggaatggc   1020

ttgccaagaa tcaccatgag gtggatcgga tcattttctg tgtcttctta gaagttgact   1080

tcaaaatcta caaaaagaaa atgaatgagt ttttctccgt agacgataat aatgaagaag   1140

aagaggatgt tgaaatgaaa gaagattcag atgagaacgg tccagaggag aagcaaagtg   1200

tggaagaaat ggaagagcag agccaagatg cagatggtgt caacactgtc actgtgcccg   1260

gccctgcttc agaagaggca gttgaagact gtaaagatga agattttgca aaggatgaaa   1320

atattacaaa aggcggtgaa gtgacagatc attctgtgcg tgaccaagat catcccgatg   1380

gacaagagaa tgattcaacg aagaatgaaa taaaaattga aacagaatcg cagagctcat   1440

atatggaaac agaagaactt tcatcaaacc aagaagatgc cgtgattgtg gagcaaccag   1500

aagtgattcc attaacagag gaccaagaag aaaaagaagg tgaaaaagct ccaggcgagg   1560

acacacctag gatgcctggg aaaagtgaag gctccagtga cctagaaaat actccaggtc   1620

ctgatgcagg ggcacaagat gaagcgaagg aacaaagaaa tggaactaaa tgacaatcct   1680

cagcatcgca aggcctctcc tggctctggg ggagctcggg aagatagcag cacacgctgt   1740

ggaggagggt gggggtgggg ggaaggcaag tcccatggaa ggacggggaa tcctttactc   1800

taatttctcc agctgcattt tgttccgttt atctgcagaa aaagaaagaa aaaaaagaaa   1860

aaaaaagttt cctttaattt ggtggaggga cccatgttga cgcatctttc aggcattatc   1920

cttgtaattt ctgtcttttc tcttacaact ttgccccagg gtcacagtgg cttgattgaa   1980

cactcacatg tgtatcctgg cccctgtctg ctttcttggt tatttcacaa agctggtcac   2040

acagtggttt attcaaagga aggggaggaa gacagtggtt tgataagctg caggataaat   2100

tttaggaatc aatgagccca gcagcagtat aatccccaga cagaggaggc aggatagaaa   2160

atgggcaaaa gcctcggaaa ccacttggaa aaggtctgga caatgaggtg aaaatatttt   2220

cttcagggtt cccaaggcac aatttgttcc aagtggctaa tgagaaatat ggaagctgaa   2280

ttttttccag agcagagtgc agaggcataa cagaagggtg ggccctggca gccatctggg   2340

tctcttcctt cctaaccatg gtggcaggtg catccttctt tgacactgac tttcagcaga   2400

gcttacttgg ttcatgaggt cttcacatgg agactaccag caagaggtga ctctctgctg   2460

cataactgta aaggatggcc ctttgctagg tgttacagtt aaaagctaag aaaaggggca   2520

gtgcatttag gacccaaaca tatgcctatg aatatcaaaa gctcctcctg aaattgctgt   2580

gagttttcca taaaagaata tcctgtcttc acccaaggct tgacagccca cagagtggtc   2640

tcatttgaaa ttacaggaaa ttagagcttt tgcttgcagt tctgccttcc tggcctgtgt   2700

ttaaatgctg tcacttgttt atgccaagtt caaggctgat tcaatggttg gtcccctcac   2760

ccagaaaacc ctgaagggga ggatacagct ctgaaggggg gcagcagtac taaaaaccca   2820

agatgccagt ggtatagtgg gcacaaggga tggcgaccat gaggatgcca ggcatcatca   2880

ccaatatcta tcctagagcc agtataaggc cagatgccta cttcccacag cctccccggg   2940

ttccaaagtc atgtcattgt tttcagtgga aacatatcgt ttgttgcata tcttcttaaa   3000

tccatcttcc ttgtaagggc tttagaacta aaacttactt atattgtttt tccttaacag   3060

agggagaaaa atagtggatt attatttcta aaataaaagg atgttctgct ttctaaatat   3120

cccatcaaaa tcttcagttt tgcacttttt tgatggaaaa ttcatcttat cttcctatga   3180

ctttggtttt agcctttctg aatttgttac cccttctgga tggcttattt gatatactgg   3240

aatagttaac aagctatact tcagcatatg cactatattc taacaaattt tttttaataa   3300

aatcaagaca tcagcaagaa tgacatttac gtgacctcat aatgtgggat tatggccttc   3360

tgttgctatt ccagtttgat atggaagcat ctatatcctc tattgccgtt agatgttgtt   3420

gcttttcaga aaagtaacga aaaggctcat tttaaagaat ccaagaaacg atgtcatcca   3480

aatattgaca gtttctacat ttcatgccat ctttataact caattgaaag ttgccgtcat   3540

tcttgtgaag tatttgacaa gtgcaatctg ctagaagctc gtttttcttg tgactcccaa   3600

atgttagtgc tacttagcct cagtaatgag ttacagttga aaaaaacatg agggaaacag   3660

agggacagag attttctaat gaacaatgat ggaagagacc taatgtcctt gctagaaaca   3720

gccaggatgg aaattatcca gccctggcat tctccttatc atcaatgaca gtcattttat   3780

tcatttattt caaatgtggg tgggctagaa gtggaaggag ggaattctct ctgcctaaaa   3840

attctagaag aatgaaagta atctttgtat ccaggaaact aagagaatga ggaataaata   3900

tcttcagccc gactcctgaa tttgtttatt cttccatcta taattagatt gtgttttcat   3960

ttttgctttg tcatgctttt tggttgttat ttggctatac agttttatgc tttaaaacaa   4020

atgataaagt taatttccaa ttcaatagtg aaatattaac aatctaacta tagccagatc   4080

aaagacacct gaacacagaa aacctttatt tgctggtgct gccattgcac aggctgtaca   4140

atgaaataga tttgaaaagc tgattgattt tcccgcacat aaattctgga tgtcaatttc   4200

caaccaaact ccaatacagc tatgtggcat gaagagttac aggagggagg gaggaaaata   4260

gccctatgtt agtcatgttt gcatacagag gatcaaagta ggccttcacc ataatagttc   4320

taattaaaat ggtcctcgct gtaggagaga caaaggggct tttcctctag ctggtaacta   4380

ttcagatgat ggacaagtct tctttcataa aagattacaa agaaggcatc cgaatcactg   4440

tctgtgatac tgggtcacat attaatcact gcagctaatt gtaaatcttt ctatgaaaca   4500

ctgaaaagcc tctttgtgaa ttaatacagt tctgcttgat gcacttgatt tgaaaagaca   4560

tttctctgta tgtggcgcat gtcggctttg ctttgaaaaa taacaaagtt agcagaatat   4620

gttcaatata ttttcttggg gaatagggtt tttattacat gattcattaa ggatttgcct   4680

taccctgaca tttgtgatat aaaggaaaat cagaaaaaaa gtaattttct tgatcaagat   4740

atgtttttac ttaatgcaaa taaatgtagt ctgttgcttg caaggaaaaa aaaatggctt   4800

ctgatatctg gtataaactg ctaaatagga taatacgtgc ctcttttgtt aaaccggcat   4860

ttaaatgctg gactgcttct aaatctgttt gtttcttttc atctgtgcca tacactaaaa   4920

aacaactgtt gccttcatac tatatttgtt agagcagaat acaaataaaa tttgtttgag   4980

aggataatgt gaaattat                                                 4998


<210>  9536
<211>  425
<212>  PRT
<213>  Homo sapiens

<400>  9536

Met Tyr Pro Ser Asn Lys Lys Lys Lys Val Trp Arg Glu Glu Lys Glu 
1               5                   10                  15


Arg Leu Leu Lys Met Thr Leu Glu Glu Arg Arg Lys Glu Tyr Leu Arg 
            20                  25                  30


Asp Tyr Ile Pro Leu Asn Ser Ile Leu Ser Trp Lys Glu Glu Met Lys 
        35                  40                  45


Gly Lys Gly Gln Asn Asp Glu Glu Asn Thr Gln Glu Thr Ser Gln Val 
    50                  55                  60


Lys Lys Ser Leu Thr Glu Lys Val Ser Leu Tyr Arg Gly Asp Ile Thr 
65                  70                  75                  80


Leu Leu Glu Val Asp Ala Ile Val Asn Ala Ala Asn Ala Ser Leu Leu 
                85                  90                  95


Gly Gly Gly Gly Val Asp Gly Cys Ile His Arg Ala Ala Gly Pro Cys 
            100                 105                 110


Leu Leu Ala Glu Cys Arg Asn Leu Asn Gly Cys Asp Thr Gly His Ala 
        115                 120                 125


Lys Ile Thr Cys Gly Tyr Asp Leu Pro Ala Lys Tyr Val Ile His Thr 
    130                 135                 140


Val Gly Pro Ile Ala Arg Gly His Ile Asn Gly Ser His Lys Glu Asp 
145                 150                 155                 160


Leu Ala Asn Cys Tyr Lys Ser Ser Leu Lys Leu Val Lys Glu Asn Asn 
                165                 170                 175


Ile Arg Ser Val Ala Phe Pro Cys Ile Ser Thr Gly Ile Tyr Gly Phe 
            180                 185                 190


Pro Asn Glu Pro Ala Ala Val Ile Ala Leu Asn Thr Ile Lys Glu Trp 
        195                 200                 205


Leu Ala Lys Asn His His Glu Val Asp Arg Ile Ile Phe Cys Val Phe 
    210                 215                 220


Leu Glu Val Asp Phe Lys Ile Tyr Lys Lys Lys Met Asn Glu Phe Phe 
225                 230                 235                 240


Ser Val Asp Asp Asn Asn Glu Glu Glu Glu Asp Val Glu Met Lys Glu 
                245                 250                 255


Asp Ser Asp Glu Asn Gly Pro Glu Glu Lys Gln Ser Val Glu Glu Met 
            260                 265                 270


Glu Glu Gln Ser Gln Asp Ala Asp Gly Val Asn Thr Val Thr Val Pro 
        275                 280                 285


Gly Pro Ala Ser Glu Glu Ala Val Glu Asp Cys Lys Asp Glu Asp Phe 
    290                 295                 300


Ala Lys Asp Glu Asn Ile Thr Lys Gly Gly Glu Val Thr Asp His Ser 
305                 310                 315                 320


Val Arg Asp Gln Asp His Pro Asp Gly Gln Glu Asn Asp Ser Thr Lys 
                325                 330                 335


Asn Glu Ile Lys Ile Glu Thr Glu Ser Gln Ser Ser Tyr Met Glu Thr 
            340                 345                 350


Glu Glu Leu Ser Ser Asn Gln Glu Asp Ala Val Ile Val Glu Gln Pro 
        355                 360                 365


Glu Val Ile Pro Leu Thr Glu Asp Gln Glu Glu Lys Glu Gly Glu Lys 
    370                 375                 380


Ala Pro Gly Glu Asp Thr Pro Arg Met Pro Gly Lys Ser Glu Gly Ser 
385                 390                 395                 400


Ser Asp Leu Glu Asn Thr Pro Gly Pro Asp Ala Gly Ala Gln Asp Glu 
                405                 410                 415


Ala Lys Glu Gln Arg Asn Gly Thr Lys 
            420                 425


<210>  9537
<211>  4674
<212>  DNA
<213>  Homo sapiens

<400>  9537
aactagcacc ctcgctgtcc ttgtgcagtg gaacgtcccc aggtctgaga atgcacctcc     60

cgccgtgtcc accccggccg cgtctctcct gaaggcagat cttggaggtg cagccaggac    120

tcctagagga gcctcctcca gtcaccatcg cgggtggggc gagccgggtc tcctgctggg    180

cttcccagcc gcttcgctcc ggacctgcct ggagcctaca aaaaacaagg gctcgtcctt    240

gcactctcgc cccccatgga tcacccctag aagtggaagg cggccgccgg gttcctcttc    300

tgtgtcatgg tttttgcatc tgctgagcga ccggtcttca cgaatcattt tcttgtggag    360

ttgcataaag ggggagagga caaagctcgc caagttgcag cagaacacgg ctttggagtc    420

cgaaagcttc cctttgctga aggtctgtac cacttttatc acaatggcct tgcaaaggcc    480

aagagaagac gcagcctaca ccacaagcag cagctggaga gagaccccag ggtaaagatg    540

gctttgcagc aggaaggatt tgaccgaaaa aagcgaggtt acagagacat caatgagatc    600

gacatcaaca tgaacgatcc tctttttaca aagcagtggt atctgatcaa tactgggcaa    660

gctgatggca ctcctggcct tgatttgaat gtggctgaag cctgggagct gggatacaca    720

gggaaaggtg ttaccattgg aattatggat gatgggattg actatctcca cccggacctg    780

gcctccaact ataatgccga agcaagttac gacttcagca gcaacgaccc ctatccttac    840

cctcggtaca cagatgactg gtttaacagc cacgggaccc gatgtgcagg agaagtttct    900

gctgccgcca acaacaatat ctgtggagtt ggagtagcat acaactccaa ggttgcaggc    960

atccggatgc tggaccagcc attcatgaca gacatcatcg aggcctcctc catcagtcat   1020

atgccacagc tgattgacat ctacagcgcc agctggggcc ccacagacaa cggcaagaca   1080

gtggatgggc cccgggagct cacgctgcag gccatggccg atggcgtgaa caagggccgc   1140

ggcggcaaag gcagcatcta cgtgtgggcc tccggggacg gcggcagcta tgacgactgc   1200

aactgcgacg gctacgcctc cagcatgtgg accatctcca tcaactcagc catcaacgac   1260

ggcaggactg ccctgtacga cgagagctgc tcttccacct tggcttccac cttcagcaac   1320

gggaggaaaa ggaaccccga ggccggtgtg gcaaccacag atttgtacgg caactgcact   1380

ctgaggcatt ctgggacatc tgcagctgcc cccgaggcag ctggtgtgtt tgcactggct   1440

ctggaggcta acctgggtct gacctggcgg gacatgcagc atctgactgt gctcacctcc   1500

aaacggaacc agcttcacga cgaggtccat cagtggcggc gcaatggggt cggcctggaa   1560

tttaatcacc tctttggcta cggggtcctt gatgcaggtg ccatggtgaa aatggctaaa   1620

gactggaaaa ccgtgcctga gagattccac tgtgtgggag gctccgtgca ggaccctgag   1680

aaaataccat ccactggcaa gttggtgctg acactcacaa ccgacgcctg tgaggggaag   1740

gaaaattttg tccgctacct ggagcatgtc caggctgtca tcacggtcaa cgcaaccaga   1800

agaggagacc tgaacatcaa catgacttcc cctatgggca ccaagtccat tttgctgagc   1860

cggcgtccaa gggatgacga ctccaaggtg ggctttgaca agtggccttt catgaccact   1920

cacacgtggg gggaagacgc ccgaggcacc tggaccctgg agctgggatt tgtcggcagc   1980

gccccgcaga agggggtgct gaaggagtgg accctgatgc tgcatggcac tcagagtgcc   2040

ccgtacatcg accaggtggt gcgggattac cagtccaagt tggccatgtc caagaaagag   2100

gagctggagg aagagctgga cgaagccgtg gagagaagcc tgaaaagcat ccttaacaag   2160

aactagcgct gcacatccgc ctttcccacc gccctccctc cccagctccg cctctgtcct   2220

cgctccacgt ttcaggcagg cacctagcaa ttccatcacc cgtacaggca attccgtctt   2280

cttaatctga agcttcactc actgtcaatg attattttca ttacaatgga aacaatcttt   2340

tttactctat gccccaaata tagcgttccc aacaacatcc atgtcctatg tgtgactcta   2400

aattctttat ttctgtcatt caaatgggtg atatcctgaa aaaaaaaaaa aaaaaaaaac   2460

tgggacagct ttcccctcat tttttttttt gtttctgaga aaagaacgta ttttaaaagc   2520

cacatagagt gactccaaga acaattgtcc atggtctcaa acaaggggct gttacataac   2580

aagaaaatca aagctgagga cagggtgtga gcgccacatc tctgaaagca caggagacac   2640

tgtgctataa atcctttggg gagcgatgtt ttgaatttag tgagatttac cagggatgta   2700

gattaaggtg atgtgattca aaagatgcca ttcatagaga gccctagtta ctgcatgggg   2760

aaagagatcc aggaagcatg agtgctggat attttactac caatgccaag ataattcact   2820

ctactcagcc ggcgtggcaa atataaaact tacagagcgt ggctgtgctc tcaccagctg   2880

ctgctctgag ttatgttaaa atccgctaga gcagcccaaa tttttctcag tttgtataga   2940

gttcatccca gccccaattt tctggggctc ctcacatagc tacccaaaag agaaaaaaaa   3000

ttaagacaag cctggcaaca cacctggtga agagtagttt actagctttt caaacaagaa   3060

tgtccctttt cctaagtcac tttgaggtgt ctcaatctga tctgagtgag aggcgacagg   3120

agtatttttt tttttttaca gctttacaca cacagatgtg ggctttgatt tccaagtaat   3180

ataatggaag agaaatctca tactccccca cagtttgatg tcattaatgt gttgggaaaa   3240

aggcctctgt cccggaagag tcatgggagg tgaaaggggc acgtttgaag atgcgagcgc   3300

tatcttcaca tagttctcca gttgtatgga gcctcttctg ccaagagagg gccatgcaat   3360

tcatcccaga ggaacctgag gcctgaagga ggtgagagaa gacctctgtg aggaaagcac   3420

acagtcacct tctcggcaac taagcagtcc ctgagaccat ttaacatgca acccgaaggt   3480

tatggtcaat cccaaaagtc accactccat tcccaactag acattaccaa agtgacctac   3540

ccagagattg cttctcatcc ccagtcccaa tgcacatcca ttcccaagaa atgctttgtc   3600

ttcagcctct ccaggcacca tctcccttcc tgtgggagca gagagcttag cctggagcac   3660

ctttccttca agccagcaac acagagcact aggttcaatt ccctgaaggt ggccacttta   3720

agagagaaat ctgaaaaccc catttgcttt cttttctccc atattggcat ggatttctgt   3780

cttctctaac accttgtgac cttctctata tcatgcttta aagtgtaata atatgatttt   3840

ttaaaagaaa tttattactt gttgcaaagg tctttttaaa ccagtttaga tttcaagaaa   3900

aaataaatgg aaatcatcga aaattcattt cacattaatg gtctaaaaat aaaccaaagg   3960

acattatgtg tgcatgtgtg tataagtgca cacagaaata tatatacata tgtagactat   4020

atacatgtgt gtatatatgt gtatatatac atacacttgt ataaatgtat atacacatat   4080

acctataatg tgtgtatgtg tatttattga agaaacagat accatactca tttctaaaag   4140

aatattcaga gaatatcaag atgattctgg ctgaaaaagg ccagtggaaa ttcaggtgaa   4200

aatgttcatc aattcccatt gcatcacctc tgtaattttt cagctctctg tataaacatt   4260

aaatgtctta tatagcagca aaaatataaa atagttgtcc atattttcac aggtgtggtg   4320

taatttataa aattagaaag caacttatca gctacttaag agaaatggca agttttgata   4380

tgagtataca atatataaaa atatatatag tgctatatat ataaatattt ggtctctatt   4440

tcattttttg catcagtatt aatactaaaa tatgtctcgc tagtgatgtt tttatgatat   4500

ccctgatcct aactgaagag acagttattt atagtcattt attttaaaaa atgaaaataa   4560

gtgaataata attaggttaa cattgttgct ccctgtgaca aaattttata agcaaatttc   4620

aaaagacatg ttgtaaatta ggaggctcaa caataaaaca ttatgctcca gaaa         4674


<210>  9538
<211>  619
<212>  PRT
<213>  Homo sapiens

<400>  9538

Met Val Phe Ala Ser Ala Glu Arg Pro Val Phe Thr Asn His Phe Leu 
1               5                   10                  15


Val Glu Leu His Lys Gly Gly Glu Asp Lys Ala Arg Gln Val Ala Ala 
            20                  25                  30


Glu His Gly Phe Gly Val Arg Lys Leu Pro Phe Ala Glu Gly Leu Tyr 
        35                  40                  45


His Phe Tyr His Asn Gly Leu Ala Lys Ala Lys Arg Arg Arg Ser Leu 
    50                  55                  60


His His Lys Gln Gln Leu Glu Arg Asp Pro Arg Val Lys Met Ala Leu 
65                  70                  75                  80


Gln Gln Glu Gly Phe Asp Arg Lys Lys Arg Gly Tyr Arg Asp Ile Asn 
                85                  90                  95


Glu Ile Asp Ile Asn Met Asn Asp Pro Leu Phe Thr Lys Gln Trp Tyr 
            100                 105                 110


Leu Ile Asn Thr Gly Gln Ala Asp Gly Thr Pro Gly Leu Asp Leu Asn 
        115                 120                 125


Val Ala Glu Ala Trp Glu Leu Gly Tyr Thr Gly Lys Gly Val Thr Ile 
    130                 135                 140


Gly Ile Met Asp Asp Gly Ile Asp Tyr Leu His Pro Asp Leu Ala Ser 
145                 150                 155                 160


Asn Tyr Asn Ala Glu Ala Ser Tyr Asp Phe Ser Ser Asn Asp Pro Tyr 
                165                 170                 175


Pro Tyr Pro Arg Tyr Thr Asp Asp Trp Phe Asn Ser His Gly Thr Arg 
            180                 185                 190


Cys Ala Gly Glu Val Ser Ala Ala Ala Asn Asn Asn Ile Cys Gly Val 
        195                 200                 205


Gly Val Ala Tyr Asn Ser Lys Val Ala Gly Ile Arg Met Leu Asp Gln 
    210                 215                 220


Pro Phe Met Thr Asp Ile Ile Glu Ala Ser Ser Ile Ser His Met Pro 
225                 230                 235                 240


Gln Leu Ile Asp Ile Tyr Ser Ala Ser Trp Gly Pro Thr Asp Asn Gly 
                245                 250                 255


Lys Thr Val Asp Gly Pro Arg Glu Leu Thr Leu Gln Ala Met Ala Asp 
            260                 265                 270


Gly Val Asn Lys Gly Arg Gly Gly Lys Gly Ser Ile Tyr Val Trp Ala 
        275                 280                 285


Ser Gly Asp Gly Gly Ser Tyr Asp Asp Cys Asn Cys Asp Gly Tyr Ala 
    290                 295                 300


Ser Ser Met Trp Thr Ile Ser Ile Asn Ser Ala Ile Asn Asp Gly Arg 
305                 310                 315                 320


Thr Ala Leu Tyr Asp Glu Ser Cys Ser Ser Thr Leu Ala Ser Thr Phe 
                325                 330                 335


Ser Asn Gly Arg Lys Arg Asn Pro Glu Ala Gly Val Ala Thr Thr Asp 
            340                 345                 350


Leu Tyr Gly Asn Cys Thr Leu Arg His Ser Gly Thr Ser Ala Ala Ala 
        355                 360                 365


Pro Glu Ala Ala Gly Val Phe Ala Leu Ala Leu Glu Ala Asn Leu Gly 
    370                 375                 380


Leu Thr Trp Arg Asp Met Gln His Leu Thr Val Leu Thr Ser Lys Arg 
385                 390                 395                 400


Asn Gln Leu His Asp Glu Val His Gln Trp Arg Arg Asn Gly Val Gly 
                405                 410                 415


Leu Glu Phe Asn His Leu Phe Gly Tyr Gly Val Leu Asp Ala Gly Ala 
            420                 425                 430


Met Val Lys Met Ala Lys Asp Trp Lys Thr Val Pro Glu Arg Phe His 
        435                 440                 445


Cys Val Gly Gly Ser Val Gln Asp Pro Glu Lys Ile Pro Ser Thr Gly 
    450                 455                 460


Lys Leu Val Leu Thr Leu Thr Thr Asp Ala Cys Glu Gly Lys Glu Asn 
465                 470                 475                 480


Phe Val Arg Tyr Leu Glu His Val Gln Ala Val Ile Thr Val Asn Ala 
                485                 490                 495


Thr Arg Arg Gly Asp Leu Asn Ile Asn Met Thr Ser Pro Met Gly Thr 
            500                 505                 510


Lys Ser Ile Leu Leu Ser Arg Arg Pro Arg Asp Asp Asp Ser Lys Val 
        515                 520                 525


Gly Phe Asp Lys Trp Pro Phe Met Thr Thr His Thr Trp Gly Glu Asp 
    530                 535                 540


Ala Arg Gly Thr Trp Thr Leu Glu Leu Gly Phe Val Gly Ser Ala Pro 
545                 550                 555                 560


Gln Lys Gly Val Leu Lys Glu Trp Thr Leu Met Leu His Gly Thr Gln 
                565                 570                 575


Ser Ala Pro Tyr Ile Asp Gln Val Val Arg Asp Tyr Gln Ser Lys Leu 
            580                 585                 590


Ala Met Ser Lys Lys Glu Glu Leu Glu Glu Glu Leu Asp Glu Ala Val 
        595                 600                 605


Glu Arg Ser Leu Lys Ser Ile Leu Asn Lys Asn 
    610                 615


<210>  9539
<211>  2485
<212>  DNA
<213>  Homo sapiens

<400>  9539
gagctggtgc tctcccccag cccctaggga attggagctg aggaggagct gaaaatgcag     60

atttagcatc aagcacagac ctacactcgc tctttctctc cggtacacac agctccccac    120

attcgcaccc ctgcccgcgc gccgggccgc ctgactgcac ggcttcccct ccagccagat    180

gctggagaac acacactgat tcgctgcttt ccaagaccct gttcagtctc tttctctata    240

caaagatttt tttaaaaact atatataaga attctttatt tgcaccctcc ctccgagtcc    300

cctgctccgc cagcctgcgc gcctcctagc accacttttc actcccaaag aaggatgaag    360

ggtggttgtg tctcccagtg gaaggcggcc gccgggttcc tcttctgtgt catggttttt    420

gcatctgctg agcgaccggt cttcacgaat cattttcttg tggagttgca taaaggggga    480

gaggacaaag ctcgccaagt tgcagcagaa cacggctttg gagtccgaaa gcttcccttt    540

gctgaaggtc tgtaccactt ttatcacaat ggccttgcaa aggccaagag aagacgcagc    600

ctacaccaca agcagcagct ggagagagac cccagggtaa agatggcttt gcagcaggaa    660

ggatttgacc gaaaaaagcg aggttacaga gacatcaatg agatcgacat caacatgaac    720

gatcctcttt ttacaaagca gtggtatctg atcaatactg ggcaagctga tggcactcct    780

ggccttgatt tgaatgtggc tgaagcctgg gagctgggat acacagggaa aggtgttacc    840

attggaatta tggatgatgg gattgactat ctccacccgg acctggcctc caactataat    900

gccgaagcaa gttacgactt cagcagcaac gacccctatc cttaccctcg gtacacagat    960

gactggttta acagccacgg gacccgatgt gcaggagaag tttctgctgc cgccaacaac   1020

aatatctgtg gagttggagt agcatacaac tccaaggttg caggcatccg gatgctggac   1080

cagccattca tgacagacat catcgaggcc tcctccatca gtcatatgcc acagctgatt   1140

gacatctaca gcgccagctg gggccccaca gacaacggca agacagtgga tgggccccgg   1200

gagctcacgc tgcaggccat ggccgatggc gtgaacaagg gccgcggcgg caaaggcagc   1260

atctacgtgt gggcctccgg ggacggcggc agctatgacg actgcaactg cgacggctac   1320

gcctccagca tgtggaccat ctccatcaac tcagccatca acgacggcag gactgccctg   1380

tacgacgaga gctgctcttc caccttggct tccaccttca gcaacgggag gaaaaggaac   1440

cccgaggccg gtgtggcaac cacagatttg tacggcaact gcactctgag gcattctggg   1500

acatctgcag ctgcccccga ggcagctggt gtgtttgcac tggctctgga ggctaacctg   1560

ggtctgacct ggcgggacat gcagcatctg actgtgctca cctccaaacg gaaccagctt   1620

cacgacgagg tccatcagtg gcggcgcaat ggggtcggcc tggaatttaa tcacctcttt   1680

ggctacgggg tccttgatgc aggtgccatg gtgaaaatgg ctaaagactg gaaaaccgtg   1740

cctgagagat tccactgtgt gggaggctcc gtgcaggacc ctgagaaaat accatccact   1800

ggcaagttgg tgctgacact cacaaccgac gcctgtgagg ggaaggaaaa ttttgtccgc   1860

tacctggagc atgtccaggc tgtcatcacg gtcaacgcaa ccagaagagg agacctgaac   1920

atcaacatga cttcccctat gggcaccaag tccattttgc tgagccggcg tccaagggat   1980

gacgactcca aggtgggctt tgacaagtgg cctttcatga ccactcacac gtggggggaa   2040

gacgcccgag gcacctggac cctggagctg ggatttgtcg gcagcgcccc gcagaagggg   2100

gtgctgaagg agtggaccct gatgctgcat ggcactcaga gtgccccgta catcgaccag   2160

gtggtgcggg attaccagtc caagttggcc atgtccaaga aagaggagct ggaggaagag   2220

ctggacgaag ccgtggagag aagcctgaaa agcatcctta acaagaacta gcgctgcaca   2280

tccgcctttc ccaccgccct ccctccccag ctccgcctct gtcctcgctc cacgtttcag   2340

gcaggcacct agcaattcca tcacccgtac aggcaattcc gtcttcttaa tctgaagctt   2400

cactcactgt caatgattat tttcattaca atggaaacaa tcttttttac tctatgcccc   2460

aaatatagcg ttcccaacaa catcc                                         2485


<210>  9540
<211>  638
<212>  PRT
<213>  Homo sapiens

<400>  9540

Met Lys Gly Gly Cys Val Ser Gln Trp Lys Ala Ala Ala Gly Phe Leu 
1               5                   10                  15


Phe Cys Val Met Val Phe Ala Ser Ala Glu Arg Pro Val Phe Thr Asn 
            20                  25                  30


His Phe Leu Val Glu Leu His Lys Gly Gly Glu Asp Lys Ala Arg Gln 
        35                  40                  45


Val Ala Ala Glu His Gly Phe Gly Val Arg Lys Leu Pro Phe Ala Glu 
    50                  55                  60


Gly Leu Tyr His Phe Tyr His Asn Gly Leu Ala Lys Ala Lys Arg Arg 
65                  70                  75                  80


Arg Ser Leu His His Lys Gln Gln Leu Glu Arg Asp Pro Arg Val Lys 
                85                  90                  95


Met Ala Leu Gln Gln Glu Gly Phe Asp Arg Lys Lys Arg Gly Tyr Arg 
            100                 105                 110


Asp Ile Asn Glu Ile Asp Ile Asn Met Asn Asp Pro Leu Phe Thr Lys 
        115                 120                 125


Gln Trp Tyr Leu Ile Asn Thr Gly Gln Ala Asp Gly Thr Pro Gly Leu 
    130                 135                 140


Asp Leu Asn Val Ala Glu Ala Trp Glu Leu Gly Tyr Thr Gly Lys Gly 
145                 150                 155                 160


Val Thr Ile Gly Ile Met Asp Asp Gly Ile Asp Tyr Leu His Pro Asp 
                165                 170                 175


Leu Ala Ser Asn Tyr Asn Ala Glu Ala Ser Tyr Asp Phe Ser Ser Asn 
            180                 185                 190


Asp Pro Tyr Pro Tyr Pro Arg Tyr Thr Asp Asp Trp Phe Asn Ser His 
        195                 200                 205


Gly Thr Arg Cys Ala Gly Glu Val Ser Ala Ala Ala Asn Asn Asn Ile 
    210                 215                 220


Cys Gly Val Gly Val Ala Tyr Asn Ser Lys Val Ala Gly Ile Arg Met 
225                 230                 235                 240


Leu Asp Gln Pro Phe Met Thr Asp Ile Ile Glu Ala Ser Ser Ile Ser 
                245                 250                 255


His Met Pro Gln Leu Ile Asp Ile Tyr Ser Ala Ser Trp Gly Pro Thr 
            260                 265                 270


Asp Asn Gly Lys Thr Val Asp Gly Pro Arg Glu Leu Thr Leu Gln Ala 
        275                 280                 285


Met Ala Asp Gly Val Asn Lys Gly Arg Gly Gly Lys Gly Ser Ile Tyr 
    290                 295                 300


Val Trp Ala Ser Gly Asp Gly Gly Ser Tyr Asp Asp Cys Asn Cys Asp 
305                 310                 315                 320


Gly Tyr Ala Ser Ser Met Trp Thr Ile Ser Ile Asn Ser Ala Ile Asn 
                325                 330                 335


Asp Gly Arg Thr Ala Leu Tyr Asp Glu Ser Cys Ser Ser Thr Leu Ala 
            340                 345                 350


Ser Thr Phe Ser Asn Gly Arg Lys Arg Asn Pro Glu Ala Gly Val Ala 
        355                 360                 365


Thr Thr Asp Leu Tyr Gly Asn Cys Thr Leu Arg His Ser Gly Thr Ser 
    370                 375                 380


Ala Ala Ala Pro Glu Ala Ala Gly Val Phe Ala Leu Ala Leu Glu Ala 
385                 390                 395                 400


Asn Leu Gly Leu Thr Trp Arg Asp Met Gln His Leu Thr Val Leu Thr 
                405                 410                 415


Ser Lys Arg Asn Gln Leu His Asp Glu Val His Gln Trp Arg Arg Asn 
            420                 425                 430


Gly Val Gly Leu Glu Phe Asn His Leu Phe Gly Tyr Gly Val Leu Asp 
        435                 440                 445


Ala Gly Ala Met Val Lys Met Ala Lys Asp Trp Lys Thr Val Pro Glu 
    450                 455                 460


Arg Phe His Cys Val Gly Gly Ser Val Gln Asp Pro Glu Lys Ile Pro 
465                 470                 475                 480


Ser Thr Gly Lys Leu Val Leu Thr Leu Thr Thr Asp Ala Cys Glu Gly 
                485                 490                 495


Lys Glu Asn Phe Val Arg Tyr Leu Glu His Val Gln Ala Val Ile Thr 
            500                 505                 510


Val Asn Ala Thr Arg Arg Gly Asp Leu Asn Ile Asn Met Thr Ser Pro 
        515                 520                 525


Met Gly Thr Lys Ser Ile Leu Leu Ser Arg Arg Pro Arg Asp Asp Asp 
    530                 535                 540


Ser Lys Val Gly Phe Asp Lys Trp Pro Phe Met Thr Thr His Thr Trp 
545                 550                 555                 560


Gly Glu Asp Ala Arg Gly Thr Trp Thr Leu Glu Leu Gly Phe Val Gly 
                565                 570                 575


Ser Ala Pro Gln Lys Gly Val Leu Lys Glu Trp Thr Leu Met Leu His 
            580                 585                 590


Gly Thr Gln Ser Ala Pro Tyr Ile Asp Gln Val Val Arg Asp Tyr Gln 
        595                 600                 605


Ser Lys Leu Ala Met Ser Lys Lys Glu Glu Leu Glu Glu Glu Leu Asp 
    610                 615                 620


Glu Ala Val Glu Arg Ser Leu Lys Ser Ile Leu Asn Lys Asn 
625                 630                 635


<210>  9541
<211>  4779
<212>  DNA
<213>  Homo sapiens

<400>  9541
gagctggtgc tctcccccag cccctaggga attggagctg aggaggagct gaaaatgcag     60

atttagcatc aagcacagac ctacactcgc tctttctctc cggtacacac agctccccac    120

attcgcaccc ctgcccgcgc gccgggccgc ctgactgcac ggcttcccct ccagccagat    180

gctggagaac acacactgat tcgctgcttt ccaagaccct gttcagtctc tttctctata    240

caaagatttt tttaaaaact atatataaga attctttatt tgcaccctcc ctccgagtcc    300

cctgctccgc cagcctgcgc gcctcctagc accacttttc actcccaaag aaggatgaag    360

ggtggttgtg tctcccagtg gaaggcggcc gccgggttcc tcttctgtgt catggttttt    420

gcatctgctg agcgaccggt cttcacgaat cattttcttg tggagttgca taaaggggga    480

gaggacaaag ctcgccaagt tgcagcagaa cacggctttg gagtccgaaa gcttcccttt    540

gctgaaggtc tgtaccactt ttatcacaat ggccttgcaa aggccaagag aagacgcagc    600

ctacaccaca agcagcagct ggagagagac cccagggtaa agatggcttt gcagcaggaa    660

ggatttgacc gaaaaaagcg aggttacaga gacatcaatg agatcgacat caacatgaac    720

gatcctcttt ttacaaagca gtggtatctg atcaatactg ggcaagctga tggcactcct    780

ggccttgatt tgaatgtggc tgaagcctgg gagctgggat acacagggaa aggtgttacc    840

attggaatta tggatgatgg gattgactat ctccacccgg acctggcctc caactataat    900

gccgaagcaa gttacgactt cagcagcaac gacccctatc cttaccctcg gtacacagat    960

gactggttta acagccacgg gacccgatgt gcaggagaag tttctgctgc cgccaacaac   1020

aatatctgtg gagttggagt agcatacaac tccaaggttg caggcatccg gatgctggac   1080

cagccattca tgacagacat catcgaggcc tcctccatca gtcatatgcc acagctgatt   1140

gacatctaca gcgccagctg gggccccaca gacaacggca agacagtgga tgggccccgg   1200

gagctcacgc tgcaggccat ggccgatggc gtgaacaagg gccgcggcgg caaaggcagc   1260

atctacgtgt gggcctccgg ggacggcggc agctatgacg actgcaactg cgacggctac   1320

gcctccagca tgtggaccat ctccatcaac tcagccatca acgacggcag gactgccctg   1380

tacgacgaga gctgctcttc caccttggct tccaccttca gcaacgggag gaaaaggaac   1440

cccgaggccg gtgtggcaac cacagatttg tacggcaact gcactctgag gcattctggg   1500

acatctgcag ctgcccccga ggcagctggt gtgtttgcac tggctctgga ggctaacctg   1560

ggtctgacct ggcgggacat gcagcatctg actgtgctca cctccaaacg gaaccagctt   1620

cacgacgagg tccatcagtg gcggcgcaat ggggtcggcc tggaatttaa tcacctcttt   1680

ggctacgggg tccttgatgc aggtgccatg gtgaaaatgg ctaaagactg gaaaaccgtg   1740

cctgagagat tccactgtgt gggaggctcc gtgcaggacc ctgagaaaat accatccact   1800

ggcaagttgg tgctgacact cacaaccgac gcctgtgagg ggaaggaaaa ttttgtccgc   1860

tacctggagc atgtccaggc tgtcatcacg gtcaacgcaa ccagaagagg agacctgaac   1920

atcaacatga cttcccctat gggcaccaag tccattttgc tgagccggcg tccaagggat   1980

gacgactcca aggtgggctt tgacaagtgg cctttcatga ccactcacac gtggggggaa   2040

gacgcccgag gcacctggac cctggagctg ggatttgtcg gcagcgcccc gcagaagggg   2100

gtgctgaagg agtggaccct gatgctgcat ggcactcaga gtgccccgta catcgaccag   2160

gtggtgcggg attaccagtc caagttggcc atgtccaaga aagaggagct ggaggaagag   2220

ctggacgaag ccgtggagag aagcctgaaa agcatcctta acaagaacta gcgctgcaca   2280

tccgcctttc ccaccgccct ccctccccag ctccgcctct gtcctcgctc cacgtttcag   2340

gcaggcacct agcaattcca tcacccgtac aggcaattcc gtcttcttaa tctgaagctt   2400

cactcactgt caatgattat tttcattaca atggaaacaa tcttttttac tctatgcccc   2460

aaatatagcg ttcccaacaa catccatgtc ctatgtgtga ctctaaattc tttatttctg   2520

tcattcaaat gggtgatatc ctgaaaaaaa aaaaaaaaaa aaaactggga cagctttccc   2580

ctcatttttt tttttgtttc tgagaaaaga acgtatttta aaagccacat agagtgactc   2640

caagaacaat tgtccatggt ctcaaacaag gggctgttac ataacaagaa aatcaaagct   2700

gaggacaggg tgtgagcgcc acatctctga aagcacagga gacactgtgc tataaatcct   2760

ttggggagcg atgttttgaa tttagtgaga tttaccaggg atgtagatta aggtgatgtg   2820

attcaaaaga tgccattcat agagagccct agttactgca tggggaaaga gatccaggaa   2880

gcatgagtgc tggatatttt actaccaatg ccaagataat tcactctact cagccggcgt   2940

ggcaaatata aaacttacag agcgtggctg tgctctcacc agctgctgct ctgagttatg   3000

ttaaaatccg ctagagcagc ccaaattttt ctcagtttgt atagagttca tcccagcccc   3060

aattttctgg ggctcctcac atagctaccc aaaagagaaa aaaaattaag acaagcctgg   3120

caacacacct ggtgaagagt agtttactag cttttcaaac aagaatgtcc cttttcctaa   3180

gtcactttga ggtgtctcaa tctgatctga gtgagaggcg acaggagtat tttttttttt   3240

ttacagcttt acacacacag atgtgggctt tgatttccaa gtaatataat ggaagagaaa   3300

tctcatactc ccccacagtt tgatgtcatt aatgtgttgg gaaaaaggcc tctgtcccgg   3360

aagagtcatg ggaggtgaaa ggggcacgtt tgaagatgcg agcgctatct tcacatagtt   3420

ctccagttgt atggagcctc ttctgccaag agagggccat gcaattcatc ccagaggaac   3480

ctgaggcctg aaggaggtga gagaagacct ctgtgaggaa agcacacagt caccttctcg   3540

gcaactaagc agtccctgag accatttaac atgcaacccg aaggttatgg tcaatcccaa   3600

aagtcaccac tccattccca actagacatt accaaagtga cctacccaga gattgcttct   3660

catccccagt cccaatgcac atccattccc aagaaatgct ttgtcttcag cctctccagg   3720

caccatctcc cttcctgtgg gagcagagag cttagcctgg agcacctttc cttcaagcca   3780

gcaacacaga gcactaggtt caattccctg aaggtggcca ctttaagaga gaaatctgaa   3840

aaccccattt gctttctttt ctcccatatt ggcatggatt tctgtcttct ctaacacctt   3900

gtgaccttct ctatatcatg ctttaaagtg taataatatg attttttaaa agaaatttat   3960

tacttgttgc aaaggtcttt ttaaaccagt ttagatttca agaaaaaata aatggaaatc   4020

atcgaaaatt catttcacat taatggtcta aaaataaacc aaaggacatt atgtgtgcat   4080

gtgtgtataa gtgcacacag aaatatatat acatatgtag actatataca tgtgtgtata   4140

tatgtgtata tatacataca cttgtataaa tgtatataca catataccta taatgtgtgt   4200

atgtgtattt attgaagaaa cagataccat actcatttct aaaagaatat tcagagaata   4260

tcaagatgat tctggctgaa aaaggccagt ggaaattcag gtgaaaatgt tcatcaattc   4320

ccattgcatc acctctgtaa tttttcagct ctctgtataa acattaaatg tcttatatag   4380

cagcaaaaat ataaaatagt tgtccatatt ttcacaggtg tggtgtaatt tataaaatta   4440

gaaagcaact tatcagctac ttaagagaaa tggcaagttt tgatatgagt atacaatata   4500

taaaaatata tatagtgcta tatatataaa tatttggtct ctatttcatt ttttgcatca   4560

gtattaatac taaaatatgt ctcgctagtg atgtttttat gatatccctg atcctaactg   4620

aagagacagt tatttatagt catttatttt aaaaaatgaa aataagtgaa taataattag   4680

gttaacattg ttgctccctg tgacaaaatt ttataagcaa atttcaaaag acatgttgta   4740

aattaggagg ctcaacaata aaacattatg ctccagaaa                          4779


<210>  9542
<211>  638
<212>  PRT
<213>  Homo sapiens

<400>  9542

Met Lys Gly Gly Cys Val Ser Gln Trp Lys Ala Ala Ala Gly Phe Leu 
1               5                   10                  15


Phe Cys Val Met Val Phe Ala Ser Ala Glu Arg Pro Val Phe Thr Asn 
            20                  25                  30


His Phe Leu Val Glu Leu His Lys Gly Gly Glu Asp Lys Ala Arg Gln 
        35                  40                  45


Val Ala Ala Glu His Gly Phe Gly Val Arg Lys Leu Pro Phe Ala Glu 
    50                  55                  60


Gly Leu Tyr His Phe Tyr His Asn Gly Leu Ala Lys Ala Lys Arg Arg 
65                  70                  75                  80


Arg Ser Leu His His Lys Gln Gln Leu Glu Arg Asp Pro Arg Val Lys 
                85                  90                  95


Met Ala Leu Gln Gln Glu Gly Phe Asp Arg Lys Lys Arg Gly Tyr Arg 
            100                 105                 110


Asp Ile Asn Glu Ile Asp Ile Asn Met Asn Asp Pro Leu Phe Thr Lys 
        115                 120                 125


Gln Trp Tyr Leu Ile Asn Thr Gly Gln Ala Asp Gly Thr Pro Gly Leu 
    130                 135                 140


Asp Leu Asn Val Ala Glu Ala Trp Glu Leu Gly Tyr Thr Gly Lys Gly 
145                 150                 155                 160


Val Thr Ile Gly Ile Met Asp Asp Gly Ile Asp Tyr Leu His Pro Asp 
                165                 170                 175


Leu Ala Ser Asn Tyr Asn Ala Glu Ala Ser Tyr Asp Phe Ser Ser Asn 
            180                 185                 190


Asp Pro Tyr Pro Tyr Pro Arg Tyr Thr Asp Asp Trp Phe Asn Ser His 
        195                 200                 205


Gly Thr Arg Cys Ala Gly Glu Val Ser Ala Ala Ala Asn Asn Asn Ile 
    210                 215                 220


Cys Gly Val Gly Val Ala Tyr Asn Ser Lys Val Ala Gly Ile Arg Met 
225                 230                 235                 240


Leu Asp Gln Pro Phe Met Thr Asp Ile Ile Glu Ala Ser Ser Ile Ser 
                245                 250                 255


His Met Pro Gln Leu Ile Asp Ile Tyr Ser Ala Ser Trp Gly Pro Thr 
            260                 265                 270


Asp Asn Gly Lys Thr Val Asp Gly Pro Arg Glu Leu Thr Leu Gln Ala 
        275                 280                 285


Met Ala Asp Gly Val Asn Lys Gly Arg Gly Gly Lys Gly Ser Ile Tyr 
    290                 295                 300


Val Trp Ala Ser Gly Asp Gly Gly Ser Tyr Asp Asp Cys Asn Cys Asp 
305                 310                 315                 320


Gly Tyr Ala Ser Ser Met Trp Thr Ile Ser Ile Asn Ser Ala Ile Asn 
                325                 330                 335


Asp Gly Arg Thr Ala Leu Tyr Asp Glu Ser Cys Ser Ser Thr Leu Ala 
            340                 345                 350


Ser Thr Phe Ser Asn Gly Arg Lys Arg Asn Pro Glu Ala Gly Val Ala 
        355                 360                 365


Thr Thr Asp Leu Tyr Gly Asn Cys Thr Leu Arg His Ser Gly Thr Ser 
    370                 375                 380


Ala Ala Ala Pro Glu Ala Ala Gly Val Phe Ala Leu Ala Leu Glu Ala 
385                 390                 395                 400


Asn Leu Gly Leu Thr Trp Arg Asp Met Gln His Leu Thr Val Leu Thr 
                405                 410                 415


Ser Lys Arg Asn Gln Leu His Asp Glu Val His Gln Trp Arg Arg Asn 
            420                 425                 430


Gly Val Gly Leu Glu Phe Asn His Leu Phe Gly Tyr Gly Val Leu Asp 
        435                 440                 445


Ala Gly Ala Met Val Lys Met Ala Lys Asp Trp Lys Thr Val Pro Glu 
    450                 455                 460


Arg Phe His Cys Val Gly Gly Ser Val Gln Asp Pro Glu Lys Ile Pro 
465                 470                 475                 480


Ser Thr Gly Lys Leu Val Leu Thr Leu Thr Thr Asp Ala Cys Glu Gly 
                485                 490                 495


Lys Glu Asn Phe Val Arg Tyr Leu Glu His Val Gln Ala Val Ile Thr 
            500                 505                 510


Val Asn Ala Thr Arg Arg Gly Asp Leu Asn Ile Asn Met Thr Ser Pro 
        515                 520                 525


Met Gly Thr Lys Ser Ile Leu Leu Ser Arg Arg Pro Arg Asp Asp Asp 
    530                 535                 540


Ser Lys Val Gly Phe Asp Lys Trp Pro Phe Met Thr Thr His Thr Trp 
545                 550                 555                 560


Gly Glu Asp Ala Arg Gly Thr Trp Thr Leu Glu Leu Gly Phe Val Gly 
                565                 570                 575


Ser Ala Pro Gln Lys Gly Val Leu Lys Glu Trp Thr Leu Met Leu His 
            580                 585                 590


Gly Thr Gln Ser Ala Pro Tyr Ile Asp Gln Val Val Arg Asp Tyr Gln 
        595                 600                 605


Ser Lys Leu Ala Met Ser Lys Lys Glu Glu Leu Glu Glu Glu Leu Asp 
    610                 615                 620


Glu Ala Val Glu Arg Ser Leu Lys Ser Ile Leu Asn Lys Asn 
625                 630                 635


<210>  9543
<211>  534
<212>  DNA
<213>  Homo sapiens

<400>  9543
aagataacaa taaaaacacc gaaagccaag gtgaccatgt caatctagaa ccatgggttg     60

cacgggacag agaagactga gagagaggat gcatctgaga gggctgggac gtgtgcagaa    120

gcacaagttt ggatgggaag tctccagcag gcatcctact cccccaagac agcatctttt    180

gccagttgct gtttatggat tttctccaca ctccaaatca catacttata cctccgttcc    240

tcagttacca tctttagaca acagctattc actccccaat acctaagatg agcatttagc    300

tcactactcc caatgtctga actttcatga ctatttttga ctcctgcatg agcatttcct    360

cttctgacag cagtcgctga ttcccagctc tgtaagatga ggacatcagt gcccctccct    420

ttctttctgc ttttctcttc ccttcttcaa tcactcgtgt tttgtgcctc tgcttctacc    480

acttcatagc actgtggtgt ttaatctcgg gtgcctgggc ttcctgggag agca          534


<210>  9544
<211>  77
<212>  PRT
<213>  Homo sapiens

<400>  9544

Met Gly Cys Thr Gly Gln Arg Arg Leu Arg Glu Arg Met His Leu Arg 
1               5                   10                  15


Gly Leu Gly Arg Val Gln Lys His Lys Phe Gly Trp Glu Val Ser Ser 
            20                  25                  30


Arg His Pro Thr Pro Pro Arg Gln His Leu Leu Pro Val Ala Val Tyr 
        35                  40                  45


Gly Phe Ser Pro His Ser Lys Ser His Thr Tyr Thr Ser Val Pro Gln 
    50                  55                  60


Leu Pro Ser Leu Asp Asn Ser Tyr Ser Leu Pro Asn Thr 
65                  70                  75


<210>  9545
<211>  536
<212>  DNA
<213>  Homo sapiens

<400>  9545
gttgcatgct gagtttgggg gagcagaaga gtctcgcggg gatagtcagt gcgcagggag     60

actagcacag gccggcagag aagtgaccca gccccggatt gcctggtaac cttccgttcc    120

caggaggctg ctgtgaggct cctctggctt catggagtat aatggaccca cagccatctc    180

cttccccaac accaactctg cctgcatttt aggccaggtt tgtaggagag ttgaatgaag    240

attgaatgaa tgaatgatga aaagtacaaa atgccatcac ttcacttctt tcaggaagac    300

ccaggacact ctgctgcatc ctccacctgt ttgtgaatta aatgtccatg atggctttta    360

ctaagcactt actatgtgcc aggcactgtg ctgagctctg cacctttaag aggcagcaag    420

tcgtgactgg ttcagagctg gctcagagct gcctgagttg gaagcctcgg ataggaaaat    480

ggaagcttaa agaggttaag ccctggccaa gcacagtagc tcgtgcctgt aattcc        536


<210>  9546
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  9546

Met Ser Met Met Ala Phe Thr Lys His Leu Leu Cys Ala Arg His Cys 
1               5                   10                  15


Ala Glu Leu Cys Thr Phe Lys Arg Gln Gln Val Val Thr Gly Ser Glu 
            20                  25                  30


Leu Ala Gln Ser Cys Leu Ser Trp Lys Pro Arg Ile Gly Lys Trp Lys 
        35                  40                  45


Leu Lys Glu Val Lys Pro Trp Pro Ser Thr Val Ala Arg Ala Cys Asn 
    50                  55                  60


<210>  9547
<211>  632
<212>  DNA
<213>  Homo sapiens

<400>  9547
gttcgtgtgg ctgttggcag gaggcctcag tttttcacct tctggacgcc tgcacagggc     60

tgcttaagca gcctcacaac atggcagctg actctcgcca tcgtgagtga ttcaagagag    120

agcaagatgg aagccgcaat atctatgatg acctggtcac agtctgtcat ttccacaact    180

ggtaacacag gttggccaag ttcaagcccc agttccggga tggagagctc catgccttgg    240

ccctgccagt gggacttctg catgtgctgg gagagaagaa aggtttcctt tgagccctgc    300

caggatcttg ttacagtctc cacagagcaa gacttcaggg tcagggtgtt gcattatgaa    360

gacaggagcc gtggagcctc cagcaggaga caatggcttc cattgagata atatgactta    420

acgaggccac aagtccacag ccaccactca ggaaacaata accatttcaa gagggcacag    480

gaggtgttac agagaggcgt ggtgacacac cccacccacc gtggcctcag agatggtgct    540

aagggagaaa gtttgctggg atttgtctga aaaggtcagt tattaaaaac agcttctggc    600

tgggcgcgct ggctcacacc tataatccta cc                                  632


<210>  9548
<211>  94
<212>  PRT
<213>  Homo sapiens

<400>  9548

Met Glu Ala Ala Ile Ser Met Met Thr Trp Ser Gln Ser Val Ile Ser 
1               5                   10                  15


Thr Thr Gly Asn Thr Gly Trp Pro Ser Ser Ser Pro Ser Ser Gly Met 
            20                  25                  30


Glu Ser Ser Met Pro Trp Pro Cys Gln Trp Asp Phe Cys Met Cys Trp 
        35                  40                  45


Glu Arg Arg Lys Val Ser Phe Glu Pro Cys Gln Asp Leu Val Thr Val 
    50                  55                  60


Ser Thr Glu Gln Asp Phe Arg Val Arg Val Leu His Tyr Glu Asp Arg 
65                  70                  75                  80


Ser Arg Gly Ala Ser Ser Arg Arg Gln Trp Leu Pro Leu Arg 
                85                  90


<210>  9549
<211>  1297
<212>  DNA
<213>  Homo sapiens

<400>  9549
cttgggtcct cctccctctg cctctgttca gctccacctt gatgctgact aggctgggcc     60

atgaggagag ggttagggga tagagatggg agctggggag cagggctcca ctctgagacg    120

ggggcagcct tgccggatcc agggcagagt taagcggccc cagctctgct ttcctagagc    180

tgctgagaac ccgggaaatg gtgtggaggt tccggggagc cctgccccta cctggcaacc    240

gcaatgcagc aggcaccaag ttctcctgca cattgcgaca gtgtgaccct gggctctggc    300

gggcggtagg tggggccttt ggacctacca gcagtgaggg agttaacaca gcagctgact    360

tctgtaggca aggaaaactc ccctcagaca ctttgctgcc tggcctcctg ccagcaacaa    420

gcaggagctg aaaactagaa gttgaggcgt gagtttggcc actccgtagt gtgcacttgg    480

tgagggcagc aactcgccac agctgccagg cgtctgtcca ttcacccatc tgtccatctg    540

gcagcccgct gttcagacct gtctgtctgt ccgcccatct gtaagcccat ctctgtccca    600

ttgtctatct gaccatcttt ctcttactgt cctctttgtc tagctatctg gcctatctgt    660

cgatccatct tcgtgtctgt cttcagcccc cacctgtttg tccatctgtc caattacctg    720

tgagtctatc tatgcatttt cttgtccatt catctgccca cccatctgtc cctccgtctg    780

cccaccggcc tcccctctcc ttctgggccg cagagccacg gtccaggact gcagagccat    840

ggttggcctg gtccttctgg ggctggggct ggcgctggct gtcattgtgc tggctgtggt    900

cctctctcga caccaggccc catttgaccc ccaggccttt gcccacgccg ctgttgctgc    960

tgactccaag gtctgctcaa atattgtagg ctggagcccc tgggtgcgag ttcctaagct   1020

ttctgcctgg acgtctctgg cttctctgcc cacacactcc ctgcccccag tgtccctgcc   1080

cctgccccag cacaggcatg ccaacttttg cacagaactg ggaaaccctc tgagcaggaa   1140

ccacatcctg acttctcacg ggagtcggga tccgagcaag cagcgctcag tgaaactgag   1200

caggattgcc ctggccctgg tctgtgggca cctgatggtc ctcagtccaa taagctcgga   1260

gaacactgag ttaaacaaag ggagccaggg gtcttga                            1297


<210>  9550
<211>  152
<212>  PRT
<213>  Homo sapiens

<400>  9550

Met Val Gly Leu Val Leu Leu Gly Leu Gly Leu Ala Leu Ala Val Ile 
1               5                   10                  15


Val Leu Ala Val Val Leu Ser Arg His Gln Ala Pro Phe Asp Pro Gln 
            20                  25                  30


Ala Phe Ala His Ala Ala Val Ala Ala Asp Ser Lys Val Cys Ser Asn 
        35                  40                  45


Ile Val Gly Trp Ser Pro Trp Val Arg Val Pro Lys Leu Ser Ala Trp 
    50                  55                  60


Thr Ser Leu Ala Ser Leu Pro Thr His Ser Leu Pro Pro Val Ser Leu 
65                  70                  75                  80


Pro Leu Pro Gln His Arg His Ala Asn Phe Cys Thr Glu Leu Gly Asn 
                85                  90                  95


Pro Leu Ser Arg Asn His Ile Leu Thr Ser His Gly Ser Arg Asp Pro 
            100                 105                 110


Ser Lys Gln Arg Ser Val Lys Leu Ser Arg Ile Ala Leu Ala Leu Val 
        115                 120                 125


Cys Gly His Leu Met Val Leu Ser Pro Ile Ser Ser Glu Asn Thr Glu 
    130                 135                 140


Leu Asn Lys Gly Ser Gln Gly Ser 
145                 150


<210>  9551
<211>  1108
<212>  DNA
<213>  Homo sapiens

<400>  9551
attgaatgca gcaagggtct ggaggctgag gaccaggcag acaaacattc agagttgctg     60

gaatgcgaca gagacaggga gtcagactgg tcatgcaagg tcctgggcct gcccttgggt    120

cctggggagc cacggaaggt tgtgggtgcc agagggttgt ggtcagagcc acagtcaggg    180

gccttctgag acctgtgccc cctccccacc ctccctcccc acctccctag gccagctctg    240

gggtctcggc aggtggtccg cgacatgacc tccgagttct tctctgccca gctccgggcc    300

cagatctctg acgacaccac tcacccgatc tcctactaca agcccgagtt ctacatgccg    360

gatgacgggg gcactgctca cctgtctgtg gtcgcagagg acggcagtgc tgtgtccgcc    420

accagcacca tcaacctcta ctttggctcc aaggtgcgct ccccagtcag cgggatcctg    480

ctcaataatg aaatggatga cttcagctct accagcatca ccaacgagtt tggggtaccc    540

ccctcacctg ccaatttcat ccagccaggg aagcagccgc tctcgtccat gtgcccgacg    600

atcatggtgg gccaggacgg ccaggtccgg atggtggtgg gagctgccgg gggcacgcag    660

atcaccatgg ccactgcact ggccatcatc tacaacctct ggttcggcta tgacgtgaag    720

tgggccgtgg aggagccccg gctgcacaac cagcttctgc ccaacgtcac gacagtggag    780

agaaacattg accaggaagt gactgcagcc ctggagaccc ggcaccatca cacccagatc    840

acgtccacct tcattgctgt ggtgcaagcc atcgtccgca tggctggtgg ctgggcagct    900

gcctcggact ccaggaaagg tggggaacct gctggctact gattgctcca ggcggacaag    960

gctgacaagc aatccaggaa caaaatactc accaggacga ggaagaggac tttgggggac   1020

aggcttctcc tgtgagcagc agagcagcac aataaatgag gccactgtgc caggctccag   1080

gtggcctccc tggcctgtct ccccactc                                      1108


<210>  9552
<211>  225
<212>  PRT
<213>  Homo sapiens

<400>  9552

Met Thr Ser Glu Phe Phe Ser Ala Gln Leu Arg Ala Gln Ile Ser Asp 
1               5                   10                  15


Asp Thr Thr His Pro Ile Ser Tyr Tyr Lys Pro Glu Phe Tyr Met Pro 
            20                  25                  30


Asp Asp Gly Gly Thr Ala His Leu Ser Val Val Ala Glu Asp Gly Ser 
        35                  40                  45


Ala Val Ser Ala Thr Ser Thr Ile Asn Leu Tyr Phe Gly Ser Lys Val 
    50                  55                  60


Arg Ser Pro Val Ser Gly Ile Leu Leu Asn Asn Glu Met Asp Asp Phe 
65                  70                  75                  80


Ser Ser Thr Ser Ile Thr Asn Glu Phe Gly Val Pro Pro Ser Pro Ala 
                85                  90                  95


Asn Phe Ile Gln Pro Gly Lys Gln Pro Leu Ser Ser Met Cys Pro Thr 
            100                 105                 110


Ile Met Val Gly Gln Asp Gly Gln Val Arg Met Val Val Gly Ala Ala 
        115                 120                 125


Gly Gly Thr Gln Ile Thr Met Ala Thr Ala Leu Ala Ile Ile Tyr Asn 
    130                 135                 140


Leu Trp Phe Gly Tyr Asp Val Lys Trp Ala Val Glu Glu Pro Arg Leu 
145                 150                 155                 160


His Asn Gln Leu Leu Pro Asn Val Thr Thr Val Glu Arg Asn Ile Asp 
                165                 170                 175


Gln Glu Val Thr Ala Ala Leu Glu Thr Arg His His His Thr Gln Ile 
            180                 185                 190


Thr Ser Thr Phe Ile Ala Val Val Gln Ala Ile Val Arg Met Ala Gly 
        195                 200                 205


Gly Trp Ala Ala Ala Ser Asp Ser Arg Lys Gly Gly Glu Pro Ala Gly 
    210                 215                 220


Tyr 
225


<210>  9553
<211>  977
<212>  DNA
<213>  Homo sapiens

<400>  9553
attgaatgca gcaagggtct ggaggctgag gaccaggcag acaaacattc agagttgctg     60

gaatgcgaca gagacaggga gtcagactgg tcatgcaagg ccagctctgg ggtctcggca    120

ggtggtccgc gacatgacct ccgagttctt ctctgcccag ctccgggccc agatctctga    180

cgacaccact cacccgatct cctactacaa gcccgagttc tacatgccgg atgacggggg    240

cactgctcac ctgtctgtgg tcgcagagga cggcagtgct gtgtccgcca ccagcaccat    300

caacctctac tttggctcca aggtgcgctc cccagtcagc gggatcctgc tcaataatga    360

aatggatgac ttcagctcta ccagcatcac caacgagttt ggggtacccc cctcacctgc    420

caatttcatc cagccaggga agcagccgct ctcgtccatg tgcccgacga tcatggtggg    480

ccaggacggc caggtccgga tggtggtggg agctgccggg ggcacgcaga tcaccatggc    540

cactgcactg gccatcatct acaacctctg gttcggctat gacgtgaagt gggccgtgga    600

ggagccccgg ctgcacaacc agcttctgcc caacgtcacg acagtggaga gaaacattga    660

ccaggaagtg actgcagccc tggagacccg gcaccatcac acccagatca cgtccacctt    720

cattgctgtg gtgcaagcca tcgtccgcat ggctggtggc tgggcagctg cctcggactc    780

caggaaaggt ggggaacctg ctggctactg attgctccag gcggacaagg ctgacaagca    840

atccaggaac aaaatactca ccaggacgag gaagaggact ttgggggaca ggcttctcct    900

gtgagcagca gagcagcaca ataaatgagg ccactgtgcc aggctccagg tggcctccct    960

ggcctgtctc cccactc                                                   977


<210>  9554
<211>  225
<212>  PRT
<213>  Homo sapiens

<400>  9554

Met Thr Ser Glu Phe Phe Ser Ala Gln Leu Arg Ala Gln Ile Ser Asp 
1               5                   10                  15


Asp Thr Thr His Pro Ile Ser Tyr Tyr Lys Pro Glu Phe Tyr Met Pro 
            20                  25                  30


Asp Asp Gly Gly Thr Ala His Leu Ser Val Val Ala Glu Asp Gly Ser 
        35                  40                  45


Ala Val Ser Ala Thr Ser Thr Ile Asn Leu Tyr Phe Gly Ser Lys Val 
    50                  55                  60


Arg Ser Pro Val Ser Gly Ile Leu Leu Asn Asn Glu Met Asp Asp Phe 
65                  70                  75                  80


Ser Ser Thr Ser Ile Thr Asn Glu Phe Gly Val Pro Pro Ser Pro Ala 
                85                  90                  95


Asn Phe Ile Gln Pro Gly Lys Gln Pro Leu Ser Ser Met Cys Pro Thr 
            100                 105                 110


Ile Met Val Gly Gln Asp Gly Gln Val Arg Met Val Val Gly Ala Ala 
        115                 120                 125


Gly Gly Thr Gln Ile Thr Met Ala Thr Ala Leu Ala Ile Ile Tyr Asn 
    130                 135                 140


Leu Trp Phe Gly Tyr Asp Val Lys Trp Ala Val Glu Glu Pro Arg Leu 
145                 150                 155                 160


His Asn Gln Leu Leu Pro Asn Val Thr Thr Val Glu Arg Asn Ile Asp 
                165                 170                 175


Gln Glu Val Thr Ala Ala Leu Glu Thr Arg His His His Thr Gln Ile 
            180                 185                 190


Thr Ser Thr Phe Ile Ala Val Val Gln Ala Ile Val Arg Met Ala Gly 
        195                 200                 205


Gly Trp Ala Ala Ala Ser Asp Ser Arg Lys Gly Gly Glu Pro Ala Gly 
    210                 215                 220


Tyr 
225


<210>  9555
<211>  1049
<212>  DNA
<213>  Homo sapiens

<400>  9555
ctcgagagct gggctctgcg tcctcgtcca gccgccaact cggccaaagg cgaagccagc     60

agtttcttct gctgccgggc aacgcgcctt ttaaacctga gggagtgggc gcgtgagcac    120

ttaatggcgc cggtgacaga gtgagcttaa cggattaata agcgcagcca ggccagctct    180

ggggtctcgg caggtggtcc gcgacatgac ctccgagttc ttctctgccc agctccgggc    240

ccagatctct gacgacacca ctcacccgat ctcctactac aagcccgagt tctacatgcc    300

ggatgacggg ggcactgctc acctgtctgt ggtcgcagag gacggcagtg ctgtgtccgc    360

caccagcacc atcaacctct actttggctc caaggtgcgc tccccagtca gcgggatcct    420

gctcaataat gaaatggatg acttcagctc taccagcatc accaacgagt ttggggtacc    480

cccctcacct gccaatttca tccagccagg gaagcagccg ctctcgtcca tgtgcccgac    540

gatcatggtg ggccaggacg gccaggtccg gatggtggtg ggagctgccg ggggcacgca    600

gatcaccatg gccactgcac tggccatcat ctacaacctc tggttcggct atgacgtgaa    660

gtgggccgtg gaggagcccc ggctgcacaa ccagcttctg cccaacgtca cgacagtgga    720

gagaaacatt gaccaggaag tgactgcagc cctggagacc cggcaccatc acacccagat    780

cacgtccacc ttcattgctg tggtgcaagc catcgtccgc atggctggtg gctgggcagc    840

tgcctcggac tccaggaaag gtggggaacc tgctggctac tgattgctcc aggcggacaa    900

ggctgacaag caatccagga acaaaatact caccaggacg aggaagagga ctttggggga    960

caggcttctc ctgtgagcag cagagcagca caataaatga ggccactgtg ccaggctcca   1020

ggtggcctcc ctggcctgtc tccccactc                                     1049


<210>  9556
<211>  225
<212>  PRT
<213>  Homo sapiens

<400>  9556

Met Thr Ser Glu Phe Phe Ser Ala Gln Leu Arg Ala Gln Ile Ser Asp 
1               5                   10                  15


Asp Thr Thr His Pro Ile Ser Tyr Tyr Lys Pro Glu Phe Tyr Met Pro 
            20                  25                  30


Asp Asp Gly Gly Thr Ala His Leu Ser Val Val Ala Glu Asp Gly Ser 
        35                  40                  45


Ala Val Ser Ala Thr Ser Thr Ile Asn Leu Tyr Phe Gly Ser Lys Val 
    50                  55                  60


Arg Ser Pro Val Ser Gly Ile Leu Leu Asn Asn Glu Met Asp Asp Phe 
65                  70                  75                  80


Ser Ser Thr Ser Ile Thr Asn Glu Phe Gly Val Pro Pro Ser Pro Ala 
                85                  90                  95


Asn Phe Ile Gln Pro Gly Lys Gln Pro Leu Ser Ser Met Cys Pro Thr 
            100                 105                 110


Ile Met Val Gly Gln Asp Gly Gln Val Arg Met Val Val Gly Ala Ala 
        115                 120                 125


Gly Gly Thr Gln Ile Thr Met Ala Thr Ala Leu Ala Ile Ile Tyr Asn 
    130                 135                 140


Leu Trp Phe Gly Tyr Asp Val Lys Trp Ala Val Glu Glu Pro Arg Leu 
145                 150                 155                 160


His Asn Gln Leu Leu Pro Asn Val Thr Thr Val Glu Arg Asn Ile Asp 
                165                 170                 175


Gln Glu Val Thr Ala Ala Leu Glu Thr Arg His His His Thr Gln Ile 
            180                 185                 190


Thr Ser Thr Phe Ile Ala Val Val Gln Ala Ile Val Arg Met Ala Gly 
        195                 200                 205


Gly Trp Ala Ala Ala Ser Asp Ser Arg Lys Gly Gly Glu Pro Ala Gly 
    210                 215                 220


Tyr 
225


<210>  9557
<211>  534
<212>  DNA
<213>  Homo sapiens

<400>  9557
gaaagacaga gaggcaaatg cagcgggttg ggggtggtca gcagagaggg gtcggtccat     60

tccagcttcc tgtggacact gctggctgag ggttggaggt ggggcaggaa cagactgcac    120

ctggcacaca ggccagaccc cctcaagccc ctccatggca ggaactggta ttgatcccat    180

tttaaagctg tgaaaactgc ggggaaaaaa atgaagtgac ttgcttgagg tcccagagct    240

agtggcaaaa aggagcaatg aagtccatga cggcctgagt ctgctggatg tcaagaccct    300

cagttccaac gattcgacct cattcagcat catctgctgt gctgatgtcc aggggccaga    360

gcagttattg caaaggaaga tttctctaag gctcttccta tttttctgtt agccatgcaa    420

agtttataaa cttttattag gatagcagta aattgcagag cagtgacaat atgtgaaaaa    480

ggtcttgctt cactcaatta agtatgttct ggatggttac agacttcatg tagg          534


<210>  9558
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  9558

Met Ser Arg Pro Ser Val Pro Thr Ile Arg Pro His Ser Ala Ser Ser 
1               5                   10                  15


Ala Val Leu Met Ser Arg Gly Gln Ser Ser Tyr Cys Lys Gly Arg Phe 
            20                  25                  30


Leu 



<210>  9559
<211>  2376
<212>  DNA
<213>  Homo sapiens

<400>  9559
atacgacagg aaaaatggag aatggatagt gaggcgtgat cagcaggctc ttccatgaca     60

accagcagtg ccttcttgct gcatcctctg gagagaagga gccctgcgtc ctcagggaag    120

gcagaagggc aggcaagccg gatactgtga tggtgcctct tccattcaca agggaggagc    180

cctcacagcc ttgtcatcac ctcctaaagg ccttgccttt taatttgatc acatgggcca    240

tgaagtttca acacctgaat tttggcagaa atgcattcaa accacagcag acccattatc    300

ctatttctaa ggaacctggg ataagacaag tccataggac aggcatggac aagcgtcctg    360

agccctgggg ccaggggaaa tccaaggtaa caagggaaat tggcgatccc agccaggtgc    420

atggctagag cagttctttc cttcggaagg gcagcgatgg aaatttcagc tctacttttt    480

ccttttcccg agctgtgtga tcttgagcag cttccttgca gctcatcctt catgtcctaa    540

aacagatgat acagcaacat cagcaaggtg gcagactaag gaacttcaga cactacttac    600

tacccccaga aacatttttt taaaaacaat tagaggacct ttggaaaata gtgaaaaggt    660

acaggagcca agcaactgcc cattcaagaa aaagcaacat tcaaaatgca ggagattttg    720

tggatttgta ctcccccttt ctgcaccctt ccctggcact gagcagtgtt ggtttggagg    780

aggtggcagc ccagctccca gttctttccc tctaatgtta gtgagcagag tctaacctgt    840

ctggggatgg cttgaaggat tagtcctgct ttgttcaact cagagctcag aataagagaa    900

gcagtttaat tcagattgca ggctgagaaa aagctatgga aagcagcagg aactgctctt    960

aaaaactgca gggaggctac agagactgaa gatgcctggg caagagattt caaatggaag   1020

catgtaataa accctctaag ggcacacaaa gaagctggaa caagactttt ggaaaattaa   1080

gatgtctaaa aggagccatg tttatgggga aatagttaaa gccacatgaa ggctcagacg   1140

agatgcatac tcagaaaaaa cctgagaaga tcttaagcta ctccttgggc tgactccaag   1200

gctcagaaca tgtcctgaga attagtgaag atcttcccca tcacatagcc tgtccgcaaa   1260

tactaggaga agtggctgtt ttttcaaatt cttaattctc aacaacgaca acaaaaatca   1320

caaggcgtac aaagacacca gaaaatacaa cttcttcagg gaagaaaatg aattgtcgga   1380

aaccacccgt aaatccaaga aaatgatgga gggactctct gtagtattgt gtccggaatt   1440

ggtgggttct tggtctcact gacttcaaga atgaagccgc ggaccctcgc gacggcagag   1500

accaagagaa aatactgtta catggttaca agatcaagtt cacaaggaca taaacaagat   1560

ggagacctca tcccgtttct tcgtttgttt cagggatctg taacaaagtt tattactgac   1620

cagcttgctg ggctatcttg aacagcaagc ttatggggtc ctaagctcat gttctatttt   1680

aaggtacctc tcttcatggc agaatgacac agaaagacaa attcacagca caaagttcac   1740

cagattcgtt acagcttaag actagcctca tgaatccttt ttcctattaa ttaaaacttt   1800

gcaagagata gtgattttta ccattcccgc atccattttg cacagtgaag gagtgagaga   1860

gagaagaatt gtctgcgcta tctaaggtga ggagttcagg ggggccagag aaagacccac   1920

ccattgcaga gacactgaat taatagttca ggtggcagct ggttggttga taaagaatct   1980

tttccagtcc catcagctct caacttttcc cctttgggga gaaaaagttc tccatgttcc   2040

aaagtcctgt atatgcctaa tcctgtcagc catagctgcc agcaaagagt gcaaggcaga   2100

ttaatccaaa gagaatagtg gttaaaatcc tatagtgcca agtccacttt tgaccaagag   2160

ggactttact gcaccccatc ccatccttta cctaggtaaa atgtacccca ttgcttaccc   2220

aaagtcagcc aattggtact gcagtctatt tcctttggaa tgggatagca acttagctaa   2280

aaggttagca gatttaattt ttttaagtat atttgtcact taagcttttt atttgccttt   2340

cacaaagtcg ttaaataaaa atgccaaaat cttttt                             2376


<210>  9560
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  9560

Met Lys Pro Arg Thr Leu Ala Thr Ala Glu Thr Lys Arg Lys Tyr Cys 
1               5                   10                  15


Tyr Met Val Thr Arg Ser Ser Ser Gln Gly His Lys Gln Asp Gly Asp 
            20                  25                  30


Leu Ile Pro Phe Leu Arg Leu Phe Gln Gly Ser Val Thr Lys Phe Ile 
        35                  40                  45


Thr Asp Gln Leu Ala Gly Leu Ser 
    50                  55


<210>  9561
<211>  538
<212>  DNA
<213>  Homo sapiens

<400>  9561
acgacaggaa aaatggagaa tggatagtga ggcgtgatca gcaggctctt ccatgacaac     60

cagcagggcc tgctgaatca ttcctgctcc tgtggagatg agtttggagt tttatgctaa    120

catcatctct gcttcacttt ttctccatgg cgagtaattt gaaggggatc actgaccgtg    180

ccatggcaca caaaagcaca acttcagaaa caagatgtgg ctcggggaca acttagaggt    240

tatttgagac gctgcaggtt ttcagcaggt gcttccaatc catggacttg gagaagaatg    300

tcagctaatg gctgccactg tgctgccagg cttccatcca gggactttag taaagttctg    360

ctgaaagaga tgtaaaccgg gagagggatg gaggctggat cctggagtgt gaatatttga    420

ccatccttta ccccagcagc acctccacgc aaggttttac atagcagtgg gtttgtgttc    480

ccatcaaact gggcctggtc agggtcaagc aagcccaagc ctctgccccc gcatgctg      538


<210>  9562
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9562

Met Leu Thr Ser Ser Leu Leu His Phe Phe Ser Met Ala Ser Asn Leu 
1               5                   10                  15


Lys Gly Ile Thr Asp Arg Ala Met Ala His Lys Ser Thr Thr Ser Glu 
            20                  25                  30


Thr Arg Cys Gly Ser Gly Thr Thr 
        35                  40


<210>  9563
<211>  514
<212>  DNA
<213>  Homo sapiens

<400>  9563
agcggctggg aggtgactga gtggtccagg tttacagagg aagtgcctct tgtgtgaaga     60

agcccaggct gggacgtctg gtttgtgctg cctgcagtga tgttcctgag aatttctgtc    120

ccttggggtc agggacatcc caggtgcctt tggatttctc ctgtgagtta gcagcctgga    180

acaatgggaa ggacgtggat agtttagtaa tctgggactc tttgaaatcg agggcagtaa    240

ggatacttgt cagaatttta tagcaagtca gagagaacgt tcagaacctg aacttcattc    300

ctgaagcaga tgtgaagtgg gagaccccct gcttttgatg tgagcttctg gccagggtcc    360

ccaggcaact cacctctcct ttatggtgcc ccatgggggt ttataaaggt aatcatattt    420

gggaactgta acactcacca cgaagatctg cagcttcact cctgagccca gcgagaccac    480

aagcccaccg ggaggaatga acaactccag atgc                                514


<210>  9564
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  9564

Ser Gly Arg Pro Pro Ala Phe Asp Val Ser Phe Trp Pro Gly Ser Pro 
1               5                   10                  15


Gly Asn Ser Pro Leu Leu Tyr Gly Ala Pro Trp Gly Phe Ile Lys Val 
            20                  25                  30


Ile Ile Phe Gly Asn Cys Asn Thr His His Glu Asp Leu Gln Leu His 
        35                  40                  45


Ser 



<210>  9565
<211>  2442
<212>  DNA
<213>  Homo sapiens

<400>  9565
agacactggc cgcgggccac catctggacg cgatcccccg ctagggcctc cctggtctgg     60

gccaaagttg gtggccacct tcgcgcgggc tgcgccctcc ttctcttccc tgccctcctc    120

ccccggggcc cgcgcccgct gcctccagca cgcgcgtcgg caggctcggc aagcgaagag    180

gagcggctcg ccccagggcg cccctcgccc agcctgccgg ccaggcgagc gcgacgagag    240

tctccccgca ccccttcctc tcccgggggc cgagagggtt gggctccgcc ccggcgccgc    300

agctcccgac tccccgccgc tcgggctgcc gccgctgccc cgcgcccggc gctcggggca    360

gccgggggcg caggcggaga gcgcagggcg gggagaggcg tggggagcag agcggcgctg    420

aggggagggc agaggaggag agagcctggc agcggaggag cagaggcggg cgccgcaccg    480

ccccgcacgc tcgctcgctc gggagagtcg cgggcggccg cttgggcgca cttgccgggt    540

caccttgtcc cggaggagaa atggcttccc tgaggcaagt gtaacctaca ttcccagccc    600

accagcctga cgcccagcca gggagagagt accatggatg gcatcattga acagaagagc    660

atgctggtgc acagtaaaat cagtgatgct ggcaagagga atggtttaat taacaccaga    720

aacttgatgg ccgagagcag agatggtctg gtgtctgttt acccagcgcc ccagtaccag    780

agccaccggg tgggggccag cacagtgccg gccagcctgg acagcagcag gagtgagccg    840

atgcagcagc tgctggaccc caacaccctg cagcagtcag tggagtcccg ctaccggccc    900

aacatcatcc tctattcaga gggcgtgctg cgctcctggg gggacggtgt ggccgccgac    960

tgctgcgaga ccaccttcat cgaggaccgg tcgcccacca aagacagcct cgagtacccg   1020

gatgggaagt tcattgacct ctcagctgat gacataaaaa tccacaccct gtcctacgat   1080

gtggaggagg aggaggagtt ccaggagctg gagagcgact actcaagcga cacagagagt   1140

gaggacaatt tcctcatgat gcccccgcgg gaccacctgg gcctcagtgt cttctccatg   1200

ctctgctgct tctggcctct gggcatcgca gccttctact tgtcccatga gaccaacaaa   1260

gccgtggcca agggggactt gcaccaggcc agcaccagct cccggcgggc cctattcctg   1320

gcagtgctgt ccatcaccat tgggactggc gtctatgtgg gcgtggccgt ggccctcatc   1380

gcctacctct ccaagaacaa ccacctgtga gcttcctgcg aatggagggg gagcacccgg   1440

ggccaggtct gtgtggacgt ggaggaagca ggcataccgc atgatgctgt acagtacaaa   1500

tgattgccaa atgatgccac gaagccctgg gatttcctac ccatggattt attttgtttt   1560

tatcctttaa tttcatgttc acagcactgt gtagagcacc agacagacgg gcactgctaa   1620

tccttccaaa ggaaagctcc aaagatccca gcccgcaagg ctgtctctgg atggattctg   1680

gtggatgaat ggcaacgcgg ctctctgcag cctgccagtg cccagagtgc caccgcatta   1740

gcaatataca aacagtccaa aaaagtgttt attttttatg gaatacggtg caataggcag   1800

aggacaaggg acacatcact cttctgtctg tggccctgct ggagtccttt gtgccccccg   1860

gagtccacac gccttccctg caagacgaga atggggctgg gaagaaagag gcaacaccac   1920

ggctggcagg agccccgctg cactgctctg cagacccatt ggcctgaccc tgagaagcag   1980

agccagcaaa gcccgggacc tgcccctctt tctttccctt cacaccaccc cagcctcagg   2040

atgtcaagcc acctccggaa cgtgtctaca ctccacagct accccgcagc aatacgcact   2100

cttgggacct cgctgatcta ggatggggag gcaggccacc gcccctccca agactcctca   2160

agaaagagcc ccgcggttgc tccggaaact cgaggcactg cagctatggg cactgcctca   2220

gcctaaagac acaggggcgc ctcccaatca ccgcgctggc ggatgctcac cccgtcataa   2280

gcagaaacta gtgatcctgg aaatgagatg ggccttactc tgtcgactaa atgaatagct   2340

attttcttgt cattttttaa agtgcaactc ttgcttcatg ctgcttaagt taccagatga   2400

atgctgagaa ataagtaatc acagacattt taataccatt tc                      2442


<210>  9566
<211>  258
<212>  PRT
<213>  Homo sapiens

<400>  9566

Met Asp Gly Ile Ile Glu Gln Lys Ser Met Leu Val His Ser Lys Ile 
1               5                   10                  15


Ser Asp Ala Gly Lys Arg Asn Gly Leu Ile Asn Thr Arg Asn Leu Met 
            20                  25                  30


Ala Glu Ser Arg Asp Gly Leu Val Ser Val Tyr Pro Ala Pro Gln Tyr 
        35                  40                  45


Gln Ser His Arg Val Gly Ala Ser Thr Val Pro Ala Ser Leu Asp Ser 
    50                  55                  60


Ser Arg Ser Glu Pro Met Gln Gln Leu Leu Asp Pro Asn Thr Leu Gln 
65                  70                  75                  80


Gln Ser Val Glu Ser Arg Tyr Arg Pro Asn Ile Ile Leu Tyr Ser Glu 
                85                  90                  95


Gly Val Leu Arg Ser Trp Gly Asp Gly Val Ala Ala Asp Cys Cys Glu 
            100                 105                 110


Thr Thr Phe Ile Glu Asp Arg Ser Pro Thr Lys Asp Ser Leu Glu Tyr 
        115                 120                 125


Pro Asp Gly Lys Phe Ile Asp Leu Ser Ala Asp Asp Ile Lys Ile His 
    130                 135                 140


Thr Leu Ser Tyr Asp Val Glu Glu Glu Glu Glu Phe Gln Glu Leu Glu 
145                 150                 155                 160


Ser Asp Tyr Ser Ser Asp Thr Glu Ser Glu Asp Asn Phe Leu Met Met 
                165                 170                 175


Pro Pro Arg Asp His Leu Gly Leu Ser Val Phe Ser Met Leu Cys Cys 
            180                 185                 190


Phe Trp Pro Leu Gly Ile Ala Ala Phe Tyr Leu Ser His Glu Thr Asn 
        195                 200                 205


Lys Ala Val Ala Lys Gly Asp Leu His Gln Ala Ser Thr Ser Ser Arg 
    210                 215                 220


Arg Ala Leu Phe Leu Ala Val Leu Ser Ile Thr Ile Gly Thr Gly Val 
225                 230                 235                 240


Tyr Val Gly Val Ala Val Ala Leu Ile Ala Tyr Leu Ser Lys Asn Asn 
                245                 250                 255


His Leu 



<210>  9567
<211>  2523
<212>  DNA
<213>  Homo sapiens

<400>  9567
agacactggc cgcgggccac catctggacg cgatcccccg ctagggcctc cctggtctgg     60

gccaaagttg gtggccacct tcgcgcgggc tgcgccctcc ttctcttccc tgccctcctc    120

ccccggggcc cgcgcccgct gcctccagca cgcgcgtcgg caggctcggc aagcgaagag    180

gagcggctcg ccccagggcg cccctcgccc agcctgccgg ccaggcgagc gcgacgagag    240

tctccccgca ccccttcctc tcccgggggc cgagagggtt gggctccgcc ccggcgccgc    300

agctcccgac tccccgccgc tcgggctgcc gccgctgccc cgcgcccggc gctcggggca    360

gccgggggcg caggcggaga gcgcagggcg gggagaggcg tggggagcag agcggcgctg    420

aggggagggc agaggaggag agagcctggc agcggaggag cagaggcggg cgccgcaccg    480

ccccgcacgc tcgctcgctc gggagagtcg cgggcggccg cttgggcgca cttgccgggt    540

caccttgtcc cggaggagaa atggcttccc tgaggcaagt gtaacctaca ttcccagccc    600

accagcctga cgcccagcca gggagagagt accatggatg gcatcattga acagaagagc    660

atgctggtgc acagtaaaat cagtgatgct ggcaagagga atggtttaat taacaccaga    720

aacttgatgg ccgagagcag agatggtctg gtgtctgttt acccagcgcc ccagtaccag    780

agccaccggg tgggggccag cacagtgccg gccagcctgg acagcagcag gagtgagccg    840

atgcagcagc tgctggaccc caacaccctg cagcagtcag tggagtcccg ctaccggccc    900

aacatcatcc tctattcaga gggcgtgctg cgctcctggg gggacggtgt ggccgccgac    960

tgctgcgaga ccaccttcat cgaggaccgg tcgcccacca aagacagcct cgagtacccg   1020

gatgggaagt tcattgacct ctcagctgat gacataaaaa tccacaccct gtcctacgat   1080

gtggaggagg aggaggagtt ccaggagctg gagagcgact actcaagcga cacagagagt   1140

gaggacaatt tcctcatgat gcccccgcgg gaccacctgg gcctcagtgt cttctccatg   1200

ctctgctgct tctggcctct gggcatcgca gccttctact tgtcccatga gaccaacaaa   1260

gccgtggcca agggggactt gcaccaggcc agcaccagct cccggcgggc cctattcctg   1320

gcagtgctgt ccatcaccat tgggactggc gtctatgtgg gcgtggccgt ggccctcatc   1380

gcctacctct ccaagaacaa ccacctgtga gcttcctgcg aatggagggg gagcacccgg   1440

ggccaggtct gtgtggacgt ggaggaagca ggcataccgc atgatgctgt acagtacaaa   1500

tgattgccaa atgatgccac gaagccctgg gatttcctac ccatggattt attttgtttt   1560

tatcctttaa tttcatgttc acagcactgt gtagagcacc agacagacgg gcactgctaa   1620

tccttccaaa ggaaagctcc aaagatccca gcccgcaagg ctgtctctgg atggattctg   1680

gtggatgaat ggcaacgcgg ctctctgcag cctgccagtg cccagagtgc caccgcatta   1740

gcaatataca aacagtccaa aaaagtgttt attttttatg gaatacggtg caataggcag   1800

aggacaaggg acacatcact cttctgtctg tggccctgct ggagtccttt gtgccccccg   1860

gagtccacac gccttccctg caagacgaga atggggctgg gaagaaagag gcaacaccac   1920

ggctggcagg agccccgctg cactgctctg cagacccatt ggcctgaccc tgagaagcag   1980

agccagcaaa gcccgggacc tgcccctctt tctttccctt cacaccaccc cagcctcagg   2040

atgtcaagcc acctccggaa cgtgtctaca ctccacagct accccgcagc aatacgcact   2100

cttgggacct cgctgatcta ggatggggag gcaggccacc gcccctccca agactcctca   2160

agaaagagcc ccgcggttgc tccggaaact cgaggcactg cagctatggg cactgcctca   2220

gcctaaagac acaggggcgc ctcccaatca ccgcgctggc ggatgctcac cccgtcataa   2280

gcagaaacta gtgatcctgg aaatgagatg ggccttactc tgtcgactaa atgaatagct   2340

attttcttgt cattttttaa agtgcaactc ttgcttcatg ctgcttaagt taccagatga   2400

atgctgagaa ataagtaatc acagacattt taataccatt tcattgctgt tttacgagtg   2460

ttcattactt aacaaaaaat tatcttttag ctttttcgct taagactttt ctttctgatg   2520

aat                                                                 2523


<210>  9568
<211>  258
<212>  PRT
<213>  Homo sapiens

<400>  9568

Met Asp Gly Ile Ile Glu Gln Lys Ser Met Leu Val His Ser Lys Ile 
1               5                   10                  15


Ser Asp Ala Gly Lys Arg Asn Gly Leu Ile Asn Thr Arg Asn Leu Met 
            20                  25                  30


Ala Glu Ser Arg Asp Gly Leu Val Ser Val Tyr Pro Ala Pro Gln Tyr 
        35                  40                  45


Gln Ser His Arg Val Gly Ala Ser Thr Val Pro Ala Ser Leu Asp Ser 
    50                  55                  60


Ser Arg Ser Glu Pro Met Gln Gln Leu Leu Asp Pro Asn Thr Leu Gln 
65                  70                  75                  80


Gln Ser Val Glu Ser Arg Tyr Arg Pro Asn Ile Ile Leu Tyr Ser Glu 
                85                  90                  95


Gly Val Leu Arg Ser Trp Gly Asp Gly Val Ala Ala Asp Cys Cys Glu 
            100                 105                 110


Thr Thr Phe Ile Glu Asp Arg Ser Pro Thr Lys Asp Ser Leu Glu Tyr 
        115                 120                 125


Pro Asp Gly Lys Phe Ile Asp Leu Ser Ala Asp Asp Ile Lys Ile His 
    130                 135                 140


Thr Leu Ser Tyr Asp Val Glu Glu Glu Glu Glu Phe Gln Glu Leu Glu 
145                 150                 155                 160


Ser Asp Tyr Ser Ser Asp Thr Glu Ser Glu Asp Asn Phe Leu Met Met 
                165                 170                 175


Pro Pro Arg Asp His Leu Gly Leu Ser Val Phe Ser Met Leu Cys Cys 
            180                 185                 190


Phe Trp Pro Leu Gly Ile Ala Ala Phe Tyr Leu Ser His Glu Thr Asn 
        195                 200                 205


Lys Ala Val Ala Lys Gly Asp Leu His Gln Ala Ser Thr Ser Ser Arg 
    210                 215                 220


Arg Ala Leu Phe Leu Ala Val Leu Ser Ile Thr Ile Gly Thr Gly Val 
225                 230                 235                 240


Tyr Val Gly Val Ala Val Ala Leu Ile Ala Tyr Leu Ser Lys Asn Asn 
                245                 250                 255


His Leu 



<210>  9569
<211>  1739
<212>  DNA
<213>  Homo sapiens

<400>  9569
gtttaattaa caccagaaac ttgatggccg agagcagaga tggtctggtg tctgtttacc     60

cagcgcccca gtaccagagc caccgggtgg gggccagcac agtgccggcc agcctggaca    120

gcagcaggag tgagccgatg cagcagctgc tggaccccaa caccctgcag cagtcagtgg    180

agtcccgcta ccggcccaac atcatcctct attcagaggg cgtgctgcgc tcctgggggg    240

acggtgtggc cgccgactgc tgcgagacca ccttcatcga ggaccggtcg cccaccaaag    300

acagcctcga gtacccggat gggaagttca ttgacctctc agctgatgac ataaaaatcc    360

acaccctgtc ctacgatgtg gaggaggagg aggagttcca ggagctggag agcgactact    420

caagcgacac agagagtgag gacaatttcc tcatgatgcc cccgcgggac cacctgggcc    480

tcagtgtctt ctccatgctc tgctgcttct ggcctctggg catcgcagcc ttctacttgt    540

cccatgagac caacaaagcc gtggccaagg gggacttgca ccaggccagc accagctccc    600

ggcgggccct attcctggca gtgctgtcca tcaccattgg gactggcgtc tatgtgggcg    660

tggccgtggc cctcatcgcc tacctctcca agaacaacca cctgtgagct tcctgcgaat    720

ggagggggag cacccggggc caggtctgtg tggacgtgga ggaagcaggc ataccgcatg    780

atgctgtaca gtacaaatga ttgccaaatg atgccacgaa gccctgggat ttcctaccca    840

tggatttatt ttgtttttat cctttaattt catgttcaca gcactgtgta gagcaccaga    900

cagacgggca ctgctaatcc ttccaaagga aagctccaaa gatcccagcc cgcaaggctg    960

tctctggatg gattctggtg gatgaatggc aacgcggctc tctgcagcct gccagtgccc   1020

agagtgccac cgcattagca atatacaaac agtccaaaaa agtgtttatt ttttatggaa   1080

tacggtgcaa taggcagagg acaagggaca catcactctt ctgtctgtgg ccctgctgga   1140

gtcctttgtg ccccccggag tccacacgcc ttccctgcaa gacgagaatg gggctgggaa   1200

gaaagaggca acaccacggc tggcaggagc cccgctgcac tgctctgcag acccattggc   1260

ctgaccctga gaagcagagc cagcaaagcc cgggacctgc ccctctttct ttcccttcac   1320

accaccccag cctcaggatg tcaagccacc tccggaacgt gtctacactc cacagctacc   1380

ccgcagcaat acgcactctt gggacctcgc tgatctagga tggggaggca ggccaccgcc   1440

cctcccaaga ctcctcaaga aagagccccg cggttgctcc ggaaactcga ggcactgcag   1500

ctatgggcac tgcctcagcc taaagacaca ggggcgcctc ccaatcaccg cgctggcgga   1560

tgctcacccc gtcataagca gaaactagtg atcctggaaa tgagatgggc cttactctgt   1620

cgactaaatg aatagctatt ttcttgtcat tttttaaagt gcaactcttg cttcatgctg   1680

cttaagttac cagatgaatg ctgagaaata agtaatcaca gacattttaa taccatttc    1739


<210>  9570
<211>  227
<212>  PRT
<213>  Homo sapiens

<400>  9570

Met Ala Glu Ser Arg Asp Gly Leu Val Ser Val Tyr Pro Ala Pro Gln 
1               5                   10                  15


Tyr Gln Ser His Arg Val Gly Ala Ser Thr Val Pro Ala Ser Leu Asp 
            20                  25                  30


Ser Ser Arg Ser Glu Pro Met Gln Gln Leu Leu Asp Pro Asn Thr Leu 
        35                  40                  45


Gln Gln Ser Val Glu Ser Arg Tyr Arg Pro Asn Ile Ile Leu Tyr Ser 
    50                  55                  60


Glu Gly Val Leu Arg Ser Trp Gly Asp Gly Val Ala Ala Asp Cys Cys 
65                  70                  75                  80


Glu Thr Thr Phe Ile Glu Asp Arg Ser Pro Thr Lys Asp Ser Leu Glu 
                85                  90                  95


Tyr Pro Asp Gly Lys Phe Ile Asp Leu Ser Ala Asp Asp Ile Lys Ile 
            100                 105                 110


His Thr Leu Ser Tyr Asp Val Glu Glu Glu Glu Glu Phe Gln Glu Leu 
        115                 120                 125


Glu Ser Asp Tyr Ser Ser Asp Thr Glu Ser Glu Asp Asn Phe Leu Met 
    130                 135                 140


Met Pro Pro Arg Asp His Leu Gly Leu Ser Val Phe Ser Met Leu Cys 
145                 150                 155                 160


Cys Phe Trp Pro Leu Gly Ile Ala Ala Phe Tyr Leu Ser His Glu Thr 
                165                 170                 175


Asn Lys Ala Val Ala Lys Gly Asp Leu His Gln Ala Ser Thr Ser Ser 
            180                 185                 190


Arg Arg Ala Leu Phe Leu Ala Val Leu Ser Ile Thr Ile Gly Thr Gly 
        195                 200                 205


Val Tyr Val Gly Val Ala Val Ala Leu Ile Ala Tyr Leu Ser Lys Asn 
    210                 215                 220


Asn His Leu 
225


<210>  9571
<211>  1820
<212>  DNA
<213>  Homo sapiens

<400>  9571
gtttaattaa caccagaaac ttgatggccg agagcagaga tggtctggtg tctgtttacc     60

cagcgcccca gtaccagagc caccgggtgg gggccagcac agtgccggcc agcctggaca    120

gcagcaggag tgagccgatg cagcagctgc tggaccccaa caccctgcag cagtcagtgg    180

agtcccgcta ccggcccaac atcatcctct attcagaggg cgtgctgcgc tcctgggggg    240

acggtgtggc cgccgactgc tgcgagacca ccttcatcga ggaccggtcg cccaccaaag    300

acagcctcga gtacccggat gggaagttca ttgacctctc agctgatgac ataaaaatcc    360

acaccctgtc ctacgatgtg gaggaggagg aggagttcca ggagctggag agcgactact    420

caagcgacac agagagtgag gacaatttcc tcatgatgcc cccgcgggac cacctgggcc    480

tcagtgtctt ctccatgctc tgctgcttct ggcctctggg catcgcagcc ttctacttgt    540

cccatgagac caacaaagcc gtggccaagg gggacttgca ccaggccagc accagctccc    600

ggcgggccct attcctggca gtgctgtcca tcaccattgg gactggcgtc tatgtgggcg    660

tggccgtggc cctcatcgcc tacctctcca agaacaacca cctgtgagct tcctgcgaat    720

ggagggggag cacccggggc caggtctgtg tggacgtgga ggaagcaggc ataccgcatg    780

atgctgtaca gtacaaatga ttgccaaatg atgccacgaa gccctgggat ttcctaccca    840

tggatttatt ttgtttttat cctttaattt catgttcaca gcactgtgta gagcaccaga    900

cagacgggca ctgctaatcc ttccaaagga aagctccaaa gatcccagcc cgcaaggctg    960

tctctggatg gattctggtg gatgaatggc aacgcggctc tctgcagcct gccagtgccc   1020

agagtgccac cgcattagca atatacaaac agtccaaaaa agtgtttatt ttttatggaa   1080

tacggtgcaa taggcagagg acaagggaca catcactctt ctgtctgtgg ccctgctgga   1140

gtcctttgtg ccccccggag tccacacgcc ttccctgcaa gacgagaatg gggctgggaa   1200

gaaagaggca acaccacggc tggcaggagc cccgctgcac tgctctgcag acccattggc   1260

ctgaccctga gaagcagagc cagcaaagcc cgggacctgc ccctctttct ttcccttcac   1320

accaccccag cctcaggatg tcaagccacc tccggaacgt gtctacactc cacagctacc   1380

ccgcagcaat acgcactctt gggacctcgc tgatctagga tggggaggca ggccaccgcc   1440

cctcccaaga ctcctcaaga aagagccccg cggttgctcc ggaaactcga ggcactgcag   1500

ctatgggcac tgcctcagcc taaagacaca ggggcgcctc ccaatcaccg cgctggcgga   1560

tgctcacccc gtcataagca gaaactagtg atcctggaaa tgagatgggc cttactctgt   1620

cgactaaatg aatagctatt ttcttgtcat tttttaaagt gcaactcttg cttcatgctg   1680

cttaagttac cagatgaatg ctgagaaata agtaatcaca gacattttaa taccatttca   1740

ttgctgtttt acgagtgttc attacttaac aaaaaattat cttttagctt tttcgcttaa   1800

gacttttctt tctgatgaat                                               1820


<210>  9572
<211>  227
<212>  PRT
<213>  Homo sapiens

<400>  9572

Met Ala Glu Ser Arg Asp Gly Leu Val Ser Val Tyr Pro Ala Pro Gln 
1               5                   10                  15


Tyr Gln Ser His Arg Val Gly Ala Ser Thr Val Pro Ala Ser Leu Asp 
            20                  25                  30


Ser Ser Arg Ser Glu Pro Met Gln Gln Leu Leu Asp Pro Asn Thr Leu 
        35                  40                  45


Gln Gln Ser Val Glu Ser Arg Tyr Arg Pro Asn Ile Ile Leu Tyr Ser 
    50                  55                  60


Glu Gly Val Leu Arg Ser Trp Gly Asp Gly Val Ala Ala Asp Cys Cys 
65                  70                  75                  80


Glu Thr Thr Phe Ile Glu Asp Arg Ser Pro Thr Lys Asp Ser Leu Glu 
                85                  90                  95


Tyr Pro Asp Gly Lys Phe Ile Asp Leu Ser Ala Asp Asp Ile Lys Ile 
            100                 105                 110


His Thr Leu Ser Tyr Asp Val Glu Glu Glu Glu Glu Phe Gln Glu Leu 
        115                 120                 125


Glu Ser Asp Tyr Ser Ser Asp Thr Glu Ser Glu Asp Asn Phe Leu Met 
    130                 135                 140


Met Pro Pro Arg Asp His Leu Gly Leu Ser Val Phe Ser Met Leu Cys 
145                 150                 155                 160


Cys Phe Trp Pro Leu Gly Ile Ala Ala Phe Tyr Leu Ser His Glu Thr 
                165                 170                 175


Asn Lys Ala Val Ala Lys Gly Asp Leu His Gln Ala Ser Thr Ser Ser 
            180                 185                 190


Arg Arg Ala Leu Phe Leu Ala Val Leu Ser Ile Thr Ile Gly Thr Gly 
        195                 200                 205


Val Tyr Val Gly Val Ala Val Ala Leu Ile Ala Tyr Leu Ser Lys Asn 
    210                 215                 220


Asn His Leu 
225


<210>  9573
<211>  1226
<212>  DNA
<213>  Homo sapiens

<400>  9573
ccagctcccg gcgggcccta ttcctggcag tgctgtccat caccattggg actggcgtct     60

atgtgggcgt ggccgtggcc ctcatcgcct acctctccaa gaacaaccac ctgtgagctt    120

cctgcgaatg gagggggagc acccggggcc aggtctgtgt ggacgtggag gaagcaggca    180

taccgcatga tgctgtacag tacaaatgat tgccaaatga tgccacgaag ccctgggatt    240

tcctacccat ggatttattt tgtttttatc ctttaatttc atgttcacag cactgtgtag    300

agcaccagac agacgggcac tgctaatcct tccaaaggaa agctccaaag atcccagccc    360

gcaaggctgt ctctggatgg attctggtgg atgaatggca acgcggctct ctgcagcctg    420

ccagtgccca gagtgccacc gcattagcaa tatacaaaca gtccaaaaaa gtgtttattt    480

tttatggaat acggtgcaat aggcagagga caagggacac atcactcttc tgtctgtggc    540

cctgctggag tcctttgtgc cccccggagt ccacacgcct tccctgcaag acgagaatgg    600

ggctgggaag aaagaggcaa caccacggct ggcaggagcc ccgctgcact gctctgcaga    660

cccattggcc tgaccctgag aagcagagcc agcaaagccc gggacctgcc cctctttctt    720

tcccttcaca ccaccccagc ctcaggatgt caagccacct ccggaacgtg tctacactcc    780

acagctaccc cgcagcaata cgcactcttg ggacctcgct gatctaggat ggggaggcag    840

gccaccgccc ctcccaagac tcctcaagaa agagccccgc ggttgctccg gaaactcgag    900

gcactgcagc tatgggcact gcctcagcct aaagacacag gggcgcctcc caatcaccgc    960

gctggcggat gctcaccccg tcataagcag aaactagtga tcctggaaat gagatgggcc   1020

ttactctgtc gactaaatga atagctattt tcttgtcatt ttttaaagtg caactcttgc   1080

ttcatgctgc ttaagttacc agatgaatgc tgagaaataa gtaatcacag acattttaat   1140

accatttcat tgctgtttta cgagtgttca ttacttaaca aaaaattatc ttttagcttt   1200

ttcgcttaag acttttcttt ttgatg                                        1226


<210>  9574
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  9574

Met Glu Tyr Gly Ala Ile Gly Arg Gly Gln Gly Thr His His Ser Ser 
1               5                   10                  15


Val Cys Gly Pro Ala Gly Val Leu Cys Ala Pro Arg Ser Pro His Ala 
            20                  25                  30


Phe Pro Ala Arg Arg Glu Trp Gly Trp Glu Glu Arg Gly Asn Thr Thr 
        35                  40                  45


Ala Gly Arg Ser Pro Ala Ala Leu Leu Cys Arg Pro Ile Gly Leu Thr 
    50                  55                  60


Leu Arg Ser Arg Ala Ser Lys Ala Arg Asp Leu Pro Leu Phe Leu Ser 
65                  70                  75                  80


Leu His Thr Thr Pro Ala Ser Gly Cys Gln Ala Thr Ser Gly Thr Cys 
                85                  90                  95


Leu His Ser Thr Ala Thr Pro Gln Gln Tyr Ala Leu Leu Gly Pro Arg 
            100                 105                 110


<210>  9575
<211>  742
<212>  DNA
<213>  Homo sapiens

<400>  9575
aggcatgatt gcatttgtta cctctggata aatgctcatg gattgaagca cctgtttaaa     60

tcgcacccta cttctagccc tgcctccaga ctcgcctctt tgcattcagg gagcacagaa    120

atgtggaacc ccatctaatg ggttcactgg cacacagacc tcagacaagg gggagctgag    180

gactggactc tgaccactgt tttggttcta aatttcttcc tgaggcccaa gaggaggtca    240

cgtccaccag ctaaacctag cattcttttc tgctggctac aaaattttta gacaaggctt    300

tgcctcctta aacaatcgca agtttaaaaa tctttgaatc cagccatcta tgacctgtgg    360

gcccccactt ggagatgttc cacgttttta ggtcaagcca atgtacagcc tccacctatt    420

gatttatgac tttgcctgtg acctctgcct ccctcccttt aaaaactcct acctgtaagc    480

cattgaggcc aggtctaaat catgagctgc cctgcaatcg gtgcctcaat ttctctcgcc    540

gcaaccctga ggtcagcctt ggctttgctc tgctgcactg gtggacccaa gctctgttca    600

ctgttgtcag cctagggtcc tgcctccagc cctgatttct cagagattgg acttggaccc    660

tccaagcccc ctgattacaa aaggaagtga gcttgttcca agactgcagg gaagggattt    720

ccattttgag ctccataggc gg                                             742


<210>  9576
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  9576

Met Thr Leu Pro Val Thr Ser Ala Ser Leu Pro Leu Lys Thr Pro Thr 
1               5                   10                  15


Cys Lys Pro Leu Arg Pro Gly Leu Asn His Glu Leu Pro Cys Asn Arg 
            20                  25                  30


Cys Leu Asn Phe Ser Arg Arg Asn Pro Glu Val Ser Leu Gly Phe Ala 
        35                  40                  45


Leu Leu His Trp Trp Thr Gln Ala Leu Phe Thr Val Val Ser Leu Gly 
    50                  55                  60


Ser Cys Leu Gln Pro 
65


<210>  9577
<211>  8416
<212>  DNA
<213>  Homo sapiens

<400>  9577
agtttggggg gcggggcctg gccctctgcc tcggggtggg ctccgccccc gtcccccgca     60

gggccttagc agcggctgcc gcagctcaat cgcggagcaa ctagccgggc gtctgcggga    120

gccgagcgtg gtgaggtggg gcctcagggg caggtgggag gtgctcgggt taaccgtccg    180

aggcccggag acccgcccgt ctagggcgcc tgagggaatc ccgttcgggc agcggcctct    240

tgttacccgg gaggaacccg aggcccagag aggggctggg acgcgtcgtt agggcccggg    300

gcccgcttgc ctcagcttct tgctgccgcc agcacgctaa gctccagtcg gcgccgaagg    360

agagcttccc gaccctcgtg tccagtagcc gcaatcccag gctgggaggg tgaggcgccg    420

cgctctgccg cccccccgcc cctcgctccc tgtgtcctgg cggatttgca cgtaatctat    480

ccgaaagccc agtcccaccc gccacccgac tctggagctc ccattcttca ggaccctgct    540

gaagtatcgc ttctcagccg ccttctccag gcgcagctgc attcgcttct cggtttttgc    600

actcgctgtg caccgagtta ctttcccggc ccctcgttga caccgttcac aggtggctgt    660

tggtctttag taagggtgag gtagagttgt tggcagaaat cctgggataa gagaatagtt    720

tcctggaaga tctgtgcctc caaccagcag agagggattg agcttcattg aactcaacag    780

agccaacatt tcatagcacc atgttcaaga ggaggttgaa gtggcatggc aatggttaga    840

gaccctgctg ggcgtgaaca ccctctggct acctagggac ctgtgggcct accacctggt    900

gccctcatgg agacaagaag ccctgggttg aacaacatga agccccagtc actgcagctg    960

gtactggaag agcaggtgct ggcactacag cagcagatgg cagagaatca ggcagcctcc   1020

tggcggaagc tgaagaactc ccaggaggcc cagcagagac aagcaaccct tgtgaggaag   1080

ctgcaggcca aggtgctgca gtaccgaagc tggtgccaag agctggagaa gcggctagaa   1140

gccactggag gaccaatccc ccagaggtgg gaaaatgtgg aggagccaaa cctggatgag   1200

ctgctggtcc gattggagga ggagcaacag aggtgtgaga gtctagcaga ggtgaacacc   1260

cagcttcgac tgcacatgga aaaagctgac gtggtgaata aagcccttag ggaagatgtg   1320

gaaaaactga cagtggactg gagccgggcc cgggatgagc taatgaggaa ggagagccag   1380

tggcagatgg agcaggagtt cttcaagggc tacctgaaag gggagcacgg tcgccttctc   1440

agtctatggc gggaggttgt gacattccga cgccacttcc tggaaatgaa gtcagctact   1500

gacagagatc tgatggagct aaaagctgag catgtgaggc tttcagggtc tctgttgacc   1560

tgttgtctgc gcttgactgt gggagcacag tctcgggaac ccaacggatc tggaagaatg   1620

gatgggcggg agccggccca gctgctgctg ctactagcca agacccagga gctggagaag   1680

gaagcccatg aaaggagcca ggagttaata cagctgaaga gtcaagggga tctggagaag   1740

gctgaacttc aggaccgggt gaccgagctc tctgctctgt tgacccagtc tcagaagcaa   1800

aatgaagatt atgaaaagat gataaaggct ctgagagaga cagtggagat cctggagaca   1860

aatcacacag aattaatgga acatgaagca tctcttagta ggaatgcgca agaggagaag   1920

ttgtctttac agcaggtgat caaggatata acccaggtca tggtggaaga aggggacaat   1980

atagcccaag gctctggtca tgagaactct ttggaattgg actctagtat cttctcccag   2040

tttgattacc aggatgcaga caaggctctt actctggtgc gttcagtgct gactcggaga   2100

cgccaggctg tgcaggacct aaggcagcag cttgcaggct gtcaagaggc tgtgaacttg   2160

ttgcaacagc agcatgatca gtgggaggaa gagggcaaag ccttgagaca gcggctgcag   2220

aagctcactg gggagcggga cactctggca gggcagactg tggacctcca gggagaggtg   2280

gactctctca gcaaggagcg agagctgctg cagaaggcca gggaagagct gcggcagcag   2340

ctggaggtgc tagagcagga ggcatggcgc ctgcgaaggg taaatgtgga gcttcagctg   2400

cagggggact ctgcccaggg ccagaaggag gaacagcagg aggagctgca cctggctgtc   2460

cgggagaggg agcgtcttca ggagatgctg atgggcctgg aagccaaaca gtcagaatca   2520

ctcagtgaac tgatcactct tcgggaagcc ctggagtcaa gtcacctgga aggggagtta   2580

ctgaggcaag agcaaacgga agtgaccgca gcgctggcta gggcagagca gtcaattgca   2640

gagctgtcga gttctgaaaa caccctgaag acagaagtag ctgatcttcg ggctgcagct   2700

gtcaagctca gtgccttaaa tgaggctttg gcgttagata aagttgggct gaaccagcag   2760

cttctccagt tagaggagga gaaccagtct gtgtgcagca gaatggaggc cgcagagcag   2820

gcgagaaatg ctttgcaggt cgacctggcg gaggcagaga agaggaggga agccctgtgg   2880

gaaaagaaca ctcacctgga ggctcagctg cagaaagctg aggaggctgg ggctgagctg   2940

caggcagatc tcagggacat ccaagaagag aaggaagaaa ttcaaaagaa actaagtgag   3000

tcacgtcacc agcaggaggc agccacgact cagctggagc agctacatca ggaggcaaag   3060

cgacaggaag aagtgcttgc cagggcagtc caggagaagg aggccctagt acgagagaaa   3120

gcggctctag aggtgcggct gcaggccgtg gagcgtgacc ggcaggacct cgctgaacaa   3180

ctacaggggc tcagctcagc caaggagcta ctggagagca gtctgtttga agcccaacaa   3240

caaaattctg tgatagaggt caccaagggg cagctggagg tccagattca aactgtcact   3300

caagccaagg aagtaatcca aggggaagtg aggtgcctga agctggaact ggacactgaa   3360

cggagtcagg cagagcagga gcgggatgct gcagccagac agctggccca ggctgagcaa   3420

gaagggaaga ctgccttgga gcagcagaag gcagcccatg agaaagaggt gaaccagctc   3480

cgggagaaat ggatgcagct ggaaacagag aaggagagag tatccctcct ggagacactg   3540

ctgcagacgc agaaggagct agcagatgcc agccaacaac tggaacgact gaggcaggac   3600

atgaaagtcc agaaattaaa ggagcaggag accactggga tactacagac ccagctccag   3660

gaggctcaac gggagctgaa ggaggcagcc cggcagcaca gagatgacct tgctgccctc   3720

caagaagaga gcagctccct gctgcaggat aagatggacc tgcagaagca ggtggaggac   3780

ttgaagtctc agctggtggc ccaggatgac tcccagaggc tggtggagca ggaggttcag   3840

gagaagctga gagagaccca ggagtataac cgaattcaga aggagctgga gagagagaaa   3900

gccagcctga ctctgtcact gatggaaaag gaacagagac tccttgtttt acaagaagct   3960

gactctattc gacaacaaga gctgagtgcc ctgcgccagg acatgcagga ggcccaggga   4020

gaacagaaag agctcagtgc tcagatggaa ttactaaggc aagaggtgaa ggaaaaggag   4080

gctgactttc tggcccagga agcacagctg ctggaggagc tggaggcgtc tcatatcacg   4140

gagcagcagc tgcgagcctc cttgtgggcc caggaagcca aggcagccca actacagctg   4200

cgactgcgca gcacagagag ccagctagaa gcgctggccg cagagcagca gcccgggaac   4260

caggcccagg cccaggccca gctggccagc ctctactctg ccctgcagca ggccctgggg   4320

tctgtttgtg agagcaggcc tgagctgagt ggtgggggag actctgctcc ttccgtctgg   4380

ggccttgagc cagaccagaa tggagctagg agcctcttta agagagggcc cctgctgact   4440

gctctctccg ctgaggcagt agcatctgcc ctccacaagc ttcatcaaga cctgtggaag   4500

actcaacaga cccgggatgt tctgagggat caggtccaga aactggaaga gcgtctaact   4560

gatactgagg ctgagaagag ccaggtccac acagagttgc aggatctgca gagacagctc   4620

tcccagaatc aggaagagaa atccaagtgg gaaggaaagc agaactccct agaatctgag   4680

ctgatggaac tacatgaaac tatggcatcc ttacagagtc gcctgcggag agcagagcta   4740

cagcgaatgg aagcccaggg tgagcgagag ttacttcagg cagccaagga gaacctgaca   4800

gcccaggtgg aacacctgca agcagctgtc gtagaagcca gggctcaggc aagtgctgct   4860

ggcatcctgg aagaagacct gagaacggct cgctcagcac tgaagctgaa aaatgaggaa   4920

gtagagagtg agcgtgagag agcccaggct ctgcaagagc agggcgaact gaaggtggcc   4980

caagggaagg ctctgcaaga gaatttggcc ctcctgaccc agaccctagc tgaaagagaa   5040

gaggaggtgg agactctgcg gggacaaatc caggaactgg agaagcaacg ggaaatgcag   5100

aaggctgctt tggaattgct gtctctggac ctgaagaaga ggaaccaaga ggtagatctg   5160

cagcaagaac agattcagga gctagagaag tgtaggtctg ttttagagca tctgcccatg   5220

gccgtccagg agcgagagca gaagctgact gtgcagaggg agcagatcag agagctcgag   5280

aaggatcggg agactcagag gaacgtcttg gagcatcagc ttctagaact tgagaagaaa   5340

gaccaaatga ttgagtccca gagaggacag gttcaggacc tgaaaaagca gttggttact   5400

ctggaatgcc tggccctgga actggaggaa aaccatcaca agatggagtg ccagcaaaaa   5460

ctgatcaagg agctggaggg ccagagggaa acccagagag tggctttgac ccaccttacg   5520

ctggacctag aagaaaggag ccaggagctg caggcacaaa gcagccagat ccatgacctg   5580

gagagccaca gcaccgttct ggcaagagag ctgcaggaga gggaccagga ggtgaagtct   5640

cagcgagaac agatcgagga gctgcagagg cagaaagagc atctgactca ggatctcgag   5700

aggagagacc aggagctgat gctgcagaag gagaggattc aggttctcga ggatcagagg   5760

acccggcaga ccaagatcct ggaggaggac ctggaacaga tcaagctgtc cttgagagag   5820

cgaggccggg agctgaccac tcagaggcag ctgatgcagg aacgggcaga ggaagggaag   5880

ggcccaagta aagcacagcg cgggagccta gagcacatga agctgatcct gcgtgataag   5940

gagaaggagg tggaatgtca gcaggagcat atccatgaac tccaggagct caaagaccag   6000

ctggagcagc agctccaggg cctgcacagg aaggtaggtg agaccagcct cctcctgtcc   6060

cagcgagagc aggaaatagt ggtcctgcag cagcaactgc aggaagccag ggaacaaggg   6120

gagctgaagg agcagtcact tcagagtcaa ctggatgagg cccagagagc cctagcccag   6180

agggaccagg aactggaggc tctgcagcaa gaacagcagc aggcccaggg acaggaggag   6240

agggtgaagg aaaaggcaga cgccctccag ggagctctgg agcaagccca tatgacactg   6300

aaggagcgtc atggagagct tcaggaccac aaggaacagg cacgaaggct ggaggaagag   6360

ctggcagtgg agggacggcg ggtccaggcc ctggaggagg tgctgggaga cctaagggct   6420

gagtctcggg aacaggagaa agctctgttg gccctccagc agcagtgtgc tgagcaggca   6480

caggagcatg aggtggagac cagggccctg caggacagct ggctgcaggc ccaggcagtg   6540

ctcaaggaac gggaccagga gctggaagct ctgcgggcag aaagtcagtc ctcccggcat   6600

caggaggagg ctgcccgggc ccgggctgag gctctgcagg aggcccttgg caaggctcat   6660

gctgccctgc aggggaaaga gcagcatctc ctcgagcagg cagaattgag ccgcagtctg   6720

gaggccagca ctgcaaccct gcaagcctcc ctggatgcct gccaggcaca cagtcggcag   6780

ctggaggagg ctctgaggat acaagaaggt gagatccagg accaggatct ccgataccag   6840

gaggatgtgc agcagctgca gcaggcactt gcccagaggg atgaagagct gagacatcag   6900

caggaacggg agcagctgct ggagaagtct ctggcccaga gggtccaaga gaatatgatc   6960

caagagaagc agaatctggg gcaagagaga gaagaggagg agataagggg ccttcatcag   7020

agtgtaaggg agctacagct gactctagcc caaaaggaac aggagattct ggagctgagg   7080

gagacccagc aaaggaacaa cctggaagcc ttaccccaca gccacaaaac ctccccaatg   7140

gaggaacaat ctctaaaact tgattcttta gagcccaggc tgcagcggga gctggagcgg   7200

ctacaggcag ccctgagaca gacagaagcc agggagattg agtggaggga gaaggcccag   7260

gacttggcac tctccctagc gcagaccaag gccagtgtca gcagtctgca ggaggtagcc   7320

atgttcctac aagcctctgt cctggagcgg gactcagaac agcaaaggct gcaggatgaa   7380

ctggagctca ccagacgggc tctggagaag gagcggctac acagcccagg tgcaaccagc   7440

acagcagaac tggggtccag aggggagcag ggtgtgcagc tgggagaggt ctcaggagtg   7500

gaggctgagc ctagtcctga tggaatggag aagcagtcat ggagacaaag gcttgaacac   7560

ctgcagcaag cagtggcccg gctggagatt gacaggagca ggctgcagcg ccacaatgtc   7620

cagctgcgga gtaccttgga gcaggtggag cgagaacgga ggaagctgaa gagggaggcc   7680

atgcgtgcgg cccaggcagg gtccctagag atcagcaagg ccacggcttc ttcacccaca   7740

cagcaggatg ggagaggaca gaagaactca gatgccaagt gtgtggctga actgcagaaa   7800

gaggtggtcc tgctgcaagc tcagctgact ttggagcgga agcagaagca ggactacatc   7860

acccgctcag cacagaccag ccgtgagcta gcaggcctgc accacagcct ctcacactca   7920

cttcttgccg tggcccaggc ccctgaggcc actgtcctgg aggcagagac ccgcaggctg   7980

gatgagtccc tgactcaaag tctgacatcc ccagggccag tcctgctaca ccccagcccc   8040

agcactaccc aagccgcctc caggtagcag ccacagccag gagcacacag acagaagact   8100

gtgtcatggg tcatggcccc tccgcacacc tacaggtttg ccaaaggaaa agcctggctc   8160

tgttaggcac ccaggagccc caggtcggcg ggtgttccca ggaagaggaa gtaaatctgc   8220

aaccctgggg aggaccccaa ctcacctggg aatgaggcaa attgcatttg cttgctccct   8280

atggaatcac ccagaggggt gccttgccct ggctgaggga catgtactgc ctctcatcta   8340

gaatttattt tcctagcact tcaccacctc cttcatcttc tccttcaaca ataaaccctg   8400

agatctttgc attcat                                                   8416


<210>  9578
<211>  2386
<212>  PRT
<213>  Homo sapiens

<400>  9578

Met Glu Thr Arg Ser Pro Gly Leu Asn Asn Met Lys Pro Gln Ser Leu 
1               5                   10                  15


Gln Leu Val Leu Glu Glu Gln Val Leu Ala Leu Gln Gln Gln Met Ala 
            20                  25                  30


Glu Asn Gln Ala Ala Ser Trp Arg Lys Leu Lys Asn Ser Gln Glu Ala 
        35                  40                  45


Gln Gln Arg Gln Ala Thr Leu Val Arg Lys Leu Gln Ala Lys Val Leu 
    50                  55                  60


Gln Tyr Arg Ser Trp Cys Gln Glu Leu Glu Lys Arg Leu Glu Ala Thr 
65                  70                  75                  80


Gly Gly Pro Ile Pro Gln Arg Trp Glu Asn Val Glu Glu Pro Asn Leu 
                85                  90                  95


Asp Glu Leu Leu Val Arg Leu Glu Glu Glu Gln Gln Arg Cys Glu Ser 
            100                 105                 110


Leu Ala Glu Val Asn Thr Gln Leu Arg Leu His Met Glu Lys Ala Asp 
        115                 120                 125


Val Val Asn Lys Ala Leu Arg Glu Asp Val Glu Lys Leu Thr Val Asp 
    130                 135                 140


Trp Ser Arg Ala Arg Asp Glu Leu Met Arg Lys Glu Ser Gln Trp Gln 
145                 150                 155                 160


Met Glu Gln Glu Phe Phe Lys Gly Tyr Leu Lys Gly Glu His Gly Arg 
                165                 170                 175


Leu Leu Ser Leu Trp Arg Glu Val Val Thr Phe Arg Arg His Phe Leu 
            180                 185                 190


Glu Met Lys Ser Ala Thr Asp Arg Asp Leu Met Glu Leu Lys Ala Glu 
        195                 200                 205


His Val Arg Leu Ser Gly Ser Leu Leu Thr Cys Cys Leu Arg Leu Thr 
    210                 215                 220


Val Gly Ala Gln Ser Arg Glu Pro Asn Gly Ser Gly Arg Met Asp Gly 
225                 230                 235                 240


Arg Glu Pro Ala Gln Leu Leu Leu Leu Leu Ala Lys Thr Gln Glu Leu 
                245                 250                 255


Glu Lys Glu Ala His Glu Arg Ser Gln Glu Leu Ile Gln Leu Lys Ser 
            260                 265                 270


Gln Gly Asp Leu Glu Lys Ala Glu Leu Gln Asp Arg Val Thr Glu Leu 
        275                 280                 285


Ser Ala Leu Leu Thr Gln Ser Gln Lys Gln Asn Glu Asp Tyr Glu Lys 
    290                 295                 300


Met Ile Lys Ala Leu Arg Glu Thr Val Glu Ile Leu Glu Thr Asn His 
305                 310                 315                 320


Thr Glu Leu Met Glu His Glu Ala Ser Leu Ser Arg Asn Ala Gln Glu 
                325                 330                 335


Glu Lys Leu Ser Leu Gln Gln Val Ile Lys Asp Ile Thr Gln Val Met 
            340                 345                 350


Val Glu Glu Gly Asp Asn Ile Ala Gln Gly Ser Gly His Glu Asn Ser 
        355                 360                 365


Leu Glu Leu Asp Ser Ser Ile Phe Ser Gln Phe Asp Tyr Gln Asp Ala 
    370                 375                 380


Asp Lys Ala Leu Thr Leu Val Arg Ser Val Leu Thr Arg Arg Arg Gln 
385                 390                 395                 400


Ala Val Gln Asp Leu Arg Gln Gln Leu Ala Gly Cys Gln Glu Ala Val 
                405                 410                 415


Asn Leu Leu Gln Gln Gln His Asp Gln Trp Glu Glu Glu Gly Lys Ala 
            420                 425                 430


Leu Arg Gln Arg Leu Gln Lys Leu Thr Gly Glu Arg Asp Thr Leu Ala 
        435                 440                 445


Gly Gln Thr Val Asp Leu Gln Gly Glu Val Asp Ser Leu Ser Lys Glu 
    450                 455                 460


Arg Glu Leu Leu Gln Lys Ala Arg Glu Glu Leu Arg Gln Gln Leu Glu 
465                 470                 475                 480


Val Leu Glu Gln Glu Ala Trp Arg Leu Arg Arg Val Asn Val Glu Leu 
                485                 490                 495


Gln Leu Gln Gly Asp Ser Ala Gln Gly Gln Lys Glu Glu Gln Gln Glu 
            500                 505                 510


Glu Leu His Leu Ala Val Arg Glu Arg Glu Arg Leu Gln Glu Met Leu 
        515                 520                 525


Met Gly Leu Glu Ala Lys Gln Ser Glu Ser Leu Ser Glu Leu Ile Thr 
    530                 535                 540


Leu Arg Glu Ala Leu Glu Ser Ser His Leu Glu Gly Glu Leu Leu Arg 
545                 550                 555                 560


Gln Glu Gln Thr Glu Val Thr Ala Ala Leu Ala Arg Ala Glu Gln Ser 
                565                 570                 575


Ile Ala Glu Leu Ser Ser Ser Glu Asn Thr Leu Lys Thr Glu Val Ala 
            580                 585                 590


Asp Leu Arg Ala Ala Ala Val Lys Leu Ser Ala Leu Asn Glu Ala Leu 
        595                 600                 605


Ala Leu Asp Lys Val Gly Leu Asn Gln Gln Leu Leu Gln Leu Glu Glu 
    610                 615                 620


Glu Asn Gln Ser Val Cys Ser Arg Met Glu Ala Ala Glu Gln Ala Arg 
625                 630                 635                 640


Asn Ala Leu Gln Val Asp Leu Ala Glu Ala Glu Lys Arg Arg Glu Ala 
                645                 650                 655


Leu Trp Glu Lys Asn Thr His Leu Glu Ala Gln Leu Gln Lys Ala Glu 
            660                 665                 670


Glu Ala Gly Ala Glu Leu Gln Ala Asp Leu Arg Asp Ile Gln Glu Glu 
        675                 680                 685


Lys Glu Glu Ile Gln Lys Lys Leu Ser Glu Ser Arg His Gln Gln Glu 
    690                 695                 700


Ala Ala Thr Thr Gln Leu Glu Gln Leu His Gln Glu Ala Lys Arg Gln 
705                 710                 715                 720


Glu Glu Val Leu Ala Arg Ala Val Gln Glu Lys Glu Ala Leu Val Arg 
                725                 730                 735


Glu Lys Ala Ala Leu Glu Val Arg Leu Gln Ala Val Glu Arg Asp Arg 
            740                 745                 750


Gln Asp Leu Ala Glu Gln Leu Gln Gly Leu Ser Ser Ala Lys Glu Leu 
        755                 760                 765


Leu Glu Ser Ser Leu Phe Glu Ala Gln Gln Gln Asn Ser Val Ile Glu 
    770                 775                 780


Val Thr Lys Gly Gln Leu Glu Val Gln Ile Gln Thr Val Thr Gln Ala 
785                 790                 795                 800


Lys Glu Val Ile Gln Gly Glu Val Arg Cys Leu Lys Leu Glu Leu Asp 
                805                 810                 815


Thr Glu Arg Ser Gln Ala Glu Gln Glu Arg Asp Ala Ala Ala Arg Gln 
            820                 825                 830


Leu Ala Gln Ala Glu Gln Glu Gly Lys Thr Ala Leu Glu Gln Gln Lys 
        835                 840                 845


Ala Ala His Glu Lys Glu Val Asn Gln Leu Arg Glu Lys Trp Met Gln 
    850                 855                 860


Leu Glu Thr Glu Lys Glu Arg Val Ser Leu Leu Glu Thr Leu Leu Gln 
865                 870                 875                 880


Thr Gln Lys Glu Leu Ala Asp Ala Ser Gln Gln Leu Glu Arg Leu Arg 
                885                 890                 895


Gln Asp Met Lys Val Gln Lys Leu Lys Glu Gln Glu Thr Thr Gly Ile 
            900                 905                 910


Leu Gln Thr Gln Leu Gln Glu Ala Gln Arg Glu Leu Lys Glu Ala Ala 
        915                 920                 925


Arg Gln His Arg Asp Asp Leu Ala Ala Leu Gln Glu Glu Ser Ser Ser 
    930                 935                 940


Leu Leu Gln Asp Lys Met Asp Leu Gln Lys Gln Val Glu Asp Leu Lys 
945                 950                 955                 960


Ser Gln Leu Val Ala Gln Asp Asp Ser Gln Arg Leu Val Glu Gln Glu 
                965                 970                 975


Val Gln Glu Lys Leu Arg Glu Thr Gln Glu Tyr Asn Arg Ile Gln Lys 
            980                 985                 990


Glu Leu Glu Arg Glu Lys Ala Ser Leu Thr Leu Ser Leu Met Glu Lys 
        995                 1000                1005


Glu Gln Arg Leu Leu Val Leu Gln Glu Ala Asp Ser Ile Arg Gln Gln 
    1010                1015                1020


Glu Leu Ser Ala Leu Arg Gln Asp Met Gln Glu Ala Gln Gly Glu Gln 
1025                1030                1035                1040


Lys Glu Leu Ser Ala Gln Met Glu Leu Leu Arg Gln Glu Val Lys Glu 
                1045                1050                1055


Lys Glu Ala Asp Phe Leu Ala Gln Glu Ala Gln Leu Leu Glu Glu Leu 
            1060                1065                1070


Glu Ala Ser His Ile Thr Glu Gln Gln Leu Arg Ala Ser Leu Trp Ala 
        1075                1080                1085


Gln Glu Ala Lys Ala Ala Gln Leu Gln Leu Arg Leu Arg Ser Thr Glu 
    1090                1095                1100


Ser Gln Leu Glu Ala Leu Ala Ala Glu Gln Gln Pro Gly Asn Gln Ala 
1105                1110                1115                1120


Gln Ala Gln Ala Gln Leu Ala Ser Leu Tyr Ser Ala Leu Gln Gln Ala 
                1125                1130                1135


Leu Gly Ser Val Cys Glu Ser Arg Pro Glu Leu Ser Gly Gly Gly Asp 
            1140                1145                1150


Ser Ala Pro Ser Val Trp Gly Leu Glu Pro Asp Gln Asn Gly Ala Arg 
        1155                1160                1165


Ser Leu Phe Lys Arg Gly Pro Leu Leu Thr Ala Leu Ser Ala Glu Ala 
    1170                1175                1180


Val Ala Ser Ala Leu His Lys Leu His Gln Asp Leu Trp Lys Thr Gln 
1185                1190                1195                1200


Gln Thr Arg Asp Val Leu Arg Asp Gln Val Gln Lys Leu Glu Glu Arg 
                1205                1210                1215


Leu Thr Asp Thr Glu Ala Glu Lys Ser Gln Val His Thr Glu Leu Gln 
            1220                1225                1230


Asp Leu Gln Arg Gln Leu Ser Gln Asn Gln Glu Glu Lys Ser Lys Trp 
        1235                1240                1245


Glu Gly Lys Gln Asn Ser Leu Glu Ser Glu Leu Met Glu Leu His Glu 
    1250                1255                1260


Thr Met Ala Ser Leu Gln Ser Arg Leu Arg Arg Ala Glu Leu Gln Arg 
1265                1270                1275                1280


Met Glu Ala Gln Gly Glu Arg Glu Leu Leu Gln Ala Ala Lys Glu Asn 
                1285                1290                1295


Leu Thr Ala Gln Val Glu His Leu Gln Ala Ala Val Val Glu Ala Arg 
            1300                1305                1310


Ala Gln Ala Ser Ala Ala Gly Ile Leu Glu Glu Asp Leu Arg Thr Ala 
        1315                1320                1325


Arg Ser Ala Leu Lys Leu Lys Asn Glu Glu Val Glu Ser Glu Arg Glu 
    1330                1335                1340


Arg Ala Gln Ala Leu Gln Glu Gln Gly Glu Leu Lys Val Ala Gln Gly 
1345                1350                1355                1360


Lys Ala Leu Gln Glu Asn Leu Ala Leu Leu Thr Gln Thr Leu Ala Glu 
                1365                1370                1375


Arg Glu Glu Glu Val Glu Thr Leu Arg Gly Gln Ile Gln Glu Leu Glu 
            1380                1385                1390


Lys Gln Arg Glu Met Gln Lys Ala Ala Leu Glu Leu Leu Ser Leu Asp 
        1395                1400                1405


Leu Lys Lys Arg Asn Gln Glu Val Asp Leu Gln Gln Glu Gln Ile Gln 
    1410                1415                1420


Glu Leu Glu Lys Cys Arg Ser Val Leu Glu His Leu Pro Met Ala Val 
1425                1430                1435                1440


Gln Glu Arg Glu Gln Lys Leu Thr Val Gln Arg Glu Gln Ile Arg Glu 
                1445                1450                1455


Leu Glu Lys Asp Arg Glu Thr Gln Arg Asn Val Leu Glu His Gln Leu 
            1460                1465                1470


Leu Glu Leu Glu Lys Lys Asp Gln Met Ile Glu Ser Gln Arg Gly Gln 
        1475                1480                1485


Val Gln Asp Leu Lys Lys Gln Leu Val Thr Leu Glu Cys Leu Ala Leu 
    1490                1495                1500


Glu Leu Glu Glu Asn His His Lys Met Glu Cys Gln Gln Lys Leu Ile 
1505                1510                1515                1520


Lys Glu Leu Glu Gly Gln Arg Glu Thr Gln Arg Val Ala Leu Thr His 
                1525                1530                1535


Leu Thr Leu Asp Leu Glu Glu Arg Ser Gln Glu Leu Gln Ala Gln Ser 
            1540                1545                1550


Ser Gln Ile His Asp Leu Glu Ser His Ser Thr Val Leu Ala Arg Glu 
        1555                1560                1565


Leu Gln Glu Arg Asp Gln Glu Val Lys Ser Gln Arg Glu Gln Ile Glu 
    1570                1575                1580


Glu Leu Gln Arg Gln Lys Glu His Leu Thr Gln Asp Leu Glu Arg Arg 
1585                1590                1595                1600


Asp Gln Glu Leu Met Leu Gln Lys Glu Arg Ile Gln Val Leu Glu Asp 
                1605                1610                1615


Gln Arg Thr Arg Gln Thr Lys Ile Leu Glu Glu Asp Leu Glu Gln Ile 
            1620                1625                1630


Lys Leu Ser Leu Arg Glu Arg Gly Arg Glu Leu Thr Thr Gln Arg Gln 
        1635                1640                1645


Leu Met Gln Glu Arg Ala Glu Glu Gly Lys Gly Pro Ser Lys Ala Gln 
    1650                1655                1660


Arg Gly Ser Leu Glu His Met Lys Leu Ile Leu Arg Asp Lys Glu Lys 
1665                1670                1675                1680


Glu Val Glu Cys Gln Gln Glu His Ile His Glu Leu Gln Glu Leu Lys 
                1685                1690                1695


Asp Gln Leu Glu Gln Gln Leu Gln Gly Leu His Arg Lys Val Gly Glu 
            1700                1705                1710


Thr Ser Leu Leu Leu Ser Gln Arg Glu Gln Glu Ile Val Val Leu Gln 
        1715                1720                1725


Gln Gln Leu Gln Glu Ala Arg Glu Gln Gly Glu Leu Lys Glu Gln Ser 
    1730                1735                1740


Leu Gln Ser Gln Leu Asp Glu Ala Gln Arg Ala Leu Ala Gln Arg Asp 
1745                1750                1755                1760


Gln Glu Leu Glu Ala Leu Gln Gln Glu Gln Gln Gln Ala Gln Gly Gln 
                1765                1770                1775


Glu Glu Arg Val Lys Glu Lys Ala Asp Ala Leu Gln Gly Ala Leu Glu 
            1780                1785                1790


Gln Ala His Met Thr Leu Lys Glu Arg His Gly Glu Leu Gln Asp His 
        1795                1800                1805


Lys Glu Gln Ala Arg Arg Leu Glu Glu Glu Leu Ala Val Glu Gly Arg 
    1810                1815                1820


Arg Val Gln Ala Leu Glu Glu Val Leu Gly Asp Leu Arg Ala Glu Ser 
1825                1830                1835                1840


Arg Glu Gln Glu Lys Ala Leu Leu Ala Leu Gln Gln Gln Cys Ala Glu 
                1845                1850                1855


Gln Ala Gln Glu His Glu Val Glu Thr Arg Ala Leu Gln Asp Ser Trp 
            1860                1865                1870


Leu Gln Ala Gln Ala Val Leu Lys Glu Arg Asp Gln Glu Leu Glu Ala 
        1875                1880                1885


Leu Arg Ala Glu Ser Gln Ser Ser Arg His Gln Glu Glu Ala Ala Arg 
    1890                1895                1900


Ala Arg Ala Glu Ala Leu Gln Glu Ala Leu Gly Lys Ala His Ala Ala 
1905                1910                1915                1920


Leu Gln Gly Lys Glu Gln His Leu Leu Glu Gln Ala Glu Leu Ser Arg 
                1925                1930                1935


Ser Leu Glu Ala Ser Thr Ala Thr Leu Gln Ala Ser Leu Asp Ala Cys 
            1940                1945                1950


Gln Ala His Ser Arg Gln Leu Glu Glu Ala Leu Arg Ile Gln Glu Gly 
        1955                1960                1965


Glu Ile Gln Asp Gln Asp Leu Arg Tyr Gln Glu Asp Val Gln Gln Leu 
    1970                1975                1980


Gln Gln Ala Leu Ala Gln Arg Asp Glu Glu Leu Arg His Gln Gln Glu 
1985                1990                1995                2000


Arg Glu Gln Leu Leu Glu Lys Ser Leu Ala Gln Arg Val Gln Glu Asn 
                2005                2010                2015


Met Ile Gln Glu Lys Gln Asn Leu Gly Gln Glu Arg Glu Glu Glu Glu 
            2020                2025                2030


Ile Arg Gly Leu His Gln Ser Val Arg Glu Leu Gln Leu Thr Leu Ala 
        2035                2040                2045


Gln Lys Glu Gln Glu Ile Leu Glu Leu Arg Glu Thr Gln Gln Arg Asn 
    2050                2055                2060


Asn Leu Glu Ala Leu Pro His Ser His Lys Thr Ser Pro Met Glu Glu 
2065                2070                2075                2080


Gln Ser Leu Lys Leu Asp Ser Leu Glu Pro Arg Leu Gln Arg Glu Leu 
                2085                2090                2095


Glu Arg Leu Gln Ala Ala Leu Arg Gln Thr Glu Ala Arg Glu Ile Glu 
            2100                2105                2110


Trp Arg Glu Lys Ala Gln Asp Leu Ala Leu Ser Leu Ala Gln Thr Lys 
        2115                2120                2125


Ala Ser Val Ser Ser Leu Gln Glu Val Ala Met Phe Leu Gln Ala Ser 
    2130                2135                2140


Val Leu Glu Arg Asp Ser Glu Gln Gln Arg Leu Gln Asp Glu Leu Glu 
2145                2150                2155                2160


Leu Thr Arg Arg Ala Leu Glu Lys Glu Arg Leu His Ser Pro Gly Ala 
                2165                2170                2175


Thr Ser Thr Ala Glu Leu Gly Ser Arg Gly Glu Gln Gly Val Gln Leu 
            2180                2185                2190


Gly Glu Val Ser Gly Val Glu Ala Glu Pro Ser Pro Asp Gly Met Glu 
        2195                2200                2205


Lys Gln Ser Trp Arg Gln Arg Leu Glu His Leu Gln Gln Ala Val Ala 
    2210                2215                2220


Arg Leu Glu Ile Asp Arg Ser Arg Leu Gln Arg His Asn Val Gln Leu 
2225                2230                2235                2240


Arg Ser Thr Leu Glu Gln Val Glu Arg Glu Arg Arg Lys Leu Lys Arg 
                2245                2250                2255


Glu Ala Met Arg Ala Ala Gln Ala Gly Ser Leu Glu Ile Ser Lys Ala 
            2260                2265                2270


Thr Ala Ser Ser Pro Thr Gln Gln Asp Gly Arg Gly Gln Lys Asn Ser 
        2275                2280                2285


Asp Ala Lys Cys Val Ala Glu Leu Gln Lys Glu Val Val Leu Leu Gln 
    2290                2295                2300


Ala Gln Leu Thr Leu Glu Arg Lys Gln Lys Gln Asp Tyr Ile Thr Arg 
2305                2310                2315                2320


Ser Ala Gln Thr Ser Arg Glu Leu Ala Gly Leu His His Ser Leu Ser 
                2325                2330                2335


His Ser Leu Leu Ala Val Ala Gln Ala Pro Glu Ala Thr Val Leu Glu 
            2340                2345                2350


Ala Glu Thr Arg Arg Leu Asp Glu Ser Leu Thr Gln Ser Leu Thr Ser 
        2355                2360                2365


Pro Gly Pro Val Leu Leu His Pro Ser Pro Ser Thr Thr Gln Ala Ala 
    2370                2375                2380


Ser Arg 
2385


<210>  9579
<211>  8584
<212>  DNA
<213>  Homo sapiens

<400>  9579
agtttggggg gcggggcctg gccctctgcc tcggggtggg ctccgccccc gtcccccgca     60

gggccttagc agcggctgcc gcagctcaat cgcggagcaa ctagccgggc gtctgcggga    120

gccgagcgtg gtgaggtggg gcctcagggg caggtgggag gtgctcgggt taaccgtccg    180

aggcccggag acccgcccgt ctagggcgcc tgagggaatc ccgttcgggc agcggcctct    240

tgttacccgg gaggaacccg aggcccagag aggggctggg acgcgtcgtt agggcccggg    300

gcccgcttgc ctcagcttct tgctgccgcc agcacgctaa gctccagtcg gcgccgaagg    360

agagcttccc gaccctcgtg tccagtagcc gcaatcccag gctgggaggg tgaggcgccg    420

cgctctgccg cccccccgcc cctcgctccc tgtgtcctgg cggatttgca cgtaatctat    480

ccgaaagccc agtcccaccc gccacccgac tctggagctc ccattcttca ggaccctgct    540

gaagtatcgc ttctcagccg ccttctccag gcgcagctgc attcgcttct cggtttttgc    600

actcgctgtg caccgagtta ctttcccggc ccctcgttga caccgttcac aggtggctgt    660

tggtctttag taagggtgag gtagagttgt tggcagaaat cctgggataa gagaatagtt    720

tcctggaaga tctgtgcctc caaccagcag agagggattg agcttcattg aactcaacag    780

agccaacatt tcatagcacc atgttcaaga ggaggttgaa gtggcatggc aatggttaga    840

gaccctgctg ggcgtgaaca ccctctggct acctagggac ctgtgggcct accacctggt    900

gccctcatgg agacaagaag ccctgggttg aacaacatga agccccagtc actgcagctg    960

gtactggaag agcaggtgct ggcactacag cagcagatgg cagagaatca ggcagcctcc   1020

tggcggaagc tgaagaactc ccaggaggcc cagcagagac aagcaaccct tgtgaggaag   1080

ctgcaggcca aggtgctgca gtaccgaagc tggtgccaag agctggagaa gcggctagaa   1140

gccactggag gaccaatccc ccagaggtgg gaaaatgtgg aggagccaaa cctggatgag   1200

ctgctggtcc gattggagga ggagcaacag aggtgtgaga gtctagcaga ggtgaacacc   1260

cagcttcgac tgcacatgga aaaagctgac gtggtgaata aagcccttag ggaagatgtg   1320

gaaaaactga cagtggactg gagccgggcc cgggatgagc taatgaggaa ggagagccag   1380

tggcagatgg agcaggagtt cttcaagggc tacctgaaag gggagcacgg tcgccttctc   1440

agtctatggc gggaggttgt gacattccga cgccacttcc tggaaatgaa gtcagctact   1500

gacagagatc tgatggagct aaaagctgag catgtgaggc tttcagggtc tctgttgacc   1560

tgttgtctgc gcttgactgt gggagcacag tctcgggaac ccaacggatc tggaagaatg   1620

gatgggcggg agccggccca gctgctgctg ctactagcca agacccagga gctggagaag   1680

gaagcccatg aaaggagcca ggagttaata cagctgaaga gtcaagggga tctggagaag   1740

gctgaacttc aggaccgggt gaccgagctc tctgctctgt tgacccagtc tcagaagcaa   1800

aatgaagatt atgaaaagat gataaaggct ctgagagaga cagtggagat cctggagaca   1860

aatcacacag aattaatgga acatgaagca tctcttagta ggaatgcgca agaggagaag   1920

ttgtctttac agcaggtgat caaggatata acccaggtca tggtggaaga aggggacaat   1980

atagcccaag gctctggtca tgagaactct ttggaattgg actctagtat cttctcccag   2040

tttgattacc aggatgcaga caaggctctt actctggtgc gttcagtgct gactcggaga   2100

cgccaggctg tgcaggacct aaggcagcag cttgcaggct gtcaagaggc tgtgaacttg   2160

ttgcaacagc agcatgatca gtgggaggaa gagggcaaag ccttgagaca gcggctgcag   2220

aagctcactg gggagcggga cactctggca gggcagactg tggacctcca gggagaggtg   2280

gactctctca gcaaggagcg agagctgctg cagaaggcca gggaagagct gcggcagcag   2340

ctggaggtgc tagagcagga ggcatggcgc ctgcgaaggg taaatgtgga gcttcagctg   2400

cagggggact ctgcccaggg ccagaaggag gaacagcagg aggagctgca cctggctgtc   2460

cgggagaggg agcgtcttca ggagatgctg atgggcctgg aagccaaaca gtcagaatca   2520

ctcagtgaac tgatcactct tcgggaagcc ctggagtcaa gtcacctgga aggggagtta   2580

ctgaggcaag agcaaacgga agtgaccgca gcgctggcta gggcagagca gtcaattgca   2640

gagctgtcga gttctgaaaa caccctgaag acagaagtag ctgatcttcg ggctgcagct   2700

gtcaagctca gtgccttaaa tgaggctttg gcgttagata aagttgggct gaaccagcag   2760

cttctccagt tagaggagga gaaccagtct gtgtgcagca gaatggaggc cgcagagcag   2820

gcgagaaatg ctttgcaggt cgacctggcg gaggcagaga agaggaggga agccctgtgg   2880

gaaaagaaca ctcacctgga ggctcagctg cagaaagctg aggaggctgg ggctgagctg   2940

caggcagatc tcagggacat ccaagaagag aaggaagaaa ttcaaaagaa actaagtgag   3000

tcacgtcacc agcaggaggc agccacgact cagctggagc agctacatca ggaggcaaag   3060

cgacaggaag aagtgcttgc cagggcagtc caggagaagg aggccctagt acgagagaaa   3120

gcggctctag aggtgcggct gcaggccgtg gagcgtgacc ggcaggacct cgctgaacaa   3180

ctacaggggc tcagctcagc caaggagcta ctggagagca gtctgtttga agcccaacaa   3240

caaaattctg tgatagaggt caccaagggg cagctggagg tccagattca aactgtcact   3300

caagccaagg aagtaatcca aggggaagtg aggtgcctga agctggaact ggacactgaa   3360

cggagtcagg cagagcagga gcgggatgct gcagccagac agctggccca ggctgagcaa   3420

gaagggaaga ctgccttgga gcagcagaag gcagcccatg agaaagaggt gaaccagctc   3480

cgggagaaat gggagaagga gcgctcctgg caccagcagg agctggcaaa ggctctggag   3540

agcttagaaa gggaaaaaat ggagctggaa atgaggctaa aggagcagca gacagaaatg   3600

gaggccatcc aggcccagag ggaagaagaa cggacccagg cagagagtgc cctatgccag   3660

atgcagctgg aaacagagaa ggagagagta tccctcctgg agacactgct gcagacgcag   3720

aaggagctag cagatgccag ccaacaactg gaacgactga ggcaggacat gaaagtccag   3780

aaattaaagg agcaggagac cactgggata ctacagaccc agctccagga ggctcaacgg   3840

gagctgaagg aggcagcccg gcagcacaga gatgaccttg ctgccctcca agaagagagc   3900

agctccctgc tgcaggataa gatggacctg cagaagcagg tggaggactt gaagtctcag   3960

ctggtggccc aggatgactc ccagaggctg gtggagcagg aggttcagga gaagctgaga   4020

gagacccagg agtataaccg aattcagaag gagctggaga gagagaaagc cagcctgact   4080

ctgtcactga tggaaaagga acagagactc cttgttttac aagaagctga ctctattcga   4140

caacaagagc tgagtgccct gcgccaggac atgcaggagg cccagggaga acagaaagag   4200

ctcagtgctc agatggaatt actaaggcaa gaggtgaagg aaaaggaggc tgactttctg   4260

gcccaggaag cacagctgct ggaggagctg gaggcgtctc atatcacgga gcagcagctg   4320

cgagcctcct tgtgggccca ggaagccaag gcagcccaac tacagctgcg actgcgcagc   4380

acagagagcc agctagaagc gctggccgca gagcagcagc ccgggaacca ggcccaggcc   4440

caggcccagc tggccagcct ctactctgcc ctgcagcagg ccctggggtc tgtttgtgag   4500

agcaggcctg agctgagtgg tgggggagac tctgctcctt ccgtctgggg ccttgagcca   4560

gaccagaatg gagctaggag cctctttaag agagggcccc tgctgactgc tctctccgct   4620

gaggcagtag catctgccct ccacaagctt catcaagacc tgtggaagac tcaacagacc   4680

cgggatgttc tgagggatca ggtccagaaa ctggaagagc gtctaactga tactgaggct   4740

gagaagagcc aggtccacac agagttgcag gatctgcaga gacagctctc ccagaatcag   4800

gaagagaaat ccaagtggga aggaaagcag aactccctag aatctgagct gatggaacta   4860

catgaaacta tggcatcctt acagagtcgc ctgcggagag cagagctaca gcgaatggaa   4920

gcccagggtg agcgagagtt acttcaggca gccaaggaga acctgacagc ccaggtggaa   4980

cacctgcaag cagctgtcgt agaagccagg gctcaggcaa gtgctgctgg catcctggaa   5040

gaagacctga gaacggctcg ctcagcactg aagctgaaaa atgaggaagt agagagtgag   5100

cgtgagagag cccaggctct gcaagagcag ggcgaactga aggtggccca agggaaggct   5160

ctgcaagaga atttggccct cctgacccag accctagctg aaagagaaga ggaggtggag   5220

actctgcggg gacaaatcca ggaactggag aagcaacggg aaatgcagaa ggctgctttg   5280

gaattgctgt ctctggacct gaagaagagg aaccaagagg tagatctgca gcaagaacag   5340

attcaggagc tagagaagtg taggtctgtt ttagagcatc tgcccatggc cgtccaggag   5400

cgagagcaga agctgactgt gcagagggag cagatcagag agctcgagaa ggatcgggag   5460

actcagagga acgtcttgga gcatcagctt ctagaacttg agaagaaaga ccaaatgatt   5520

gagtcccaga gaggacaggt tcaggacctg aaaaagcagt tggttactct ggaatgcctg   5580

gccctggaac tggaggaaaa ccatcacaag atggagtgcc agcaaaaact gatcaaggag   5640

ctggagggcc agagggaaac ccagagagtg gctttgaccc accttacgct ggacctagaa   5700

gaaaggagcc aggagctgca ggcacaaagc agccagatcc atgacctgga gagccacagc   5760

accgttctgg caagagagct gcaggagagg gaccaggagg tgaagtctca gcgagaacag   5820

atcgaggagc tgcagaggca gaaagagcat ctgactcagg atctcgagag gagagaccag   5880

gagctgatgc tgcagaagga gaggattcag gttctcgagg atcagaggac ccggcagacc   5940

aagatcctgg aggaggacct ggaacagatc aagctgtcct tgagagagcg aggccgggag   6000

ctgaccactc agaggcagct gatgcaggaa cgggcagagg aagggaaggg cccaagtaaa   6060

gcacagcgcg ggagcctaga gcacatgaag ctgatcctgc gtgataagga gaaggaggtg   6120

gaatgtcagc aggagcatat ccatgaactc caggagctca aagaccagct ggagcagcag   6180

ctccagggcc tgcacaggaa ggtaggtgag accagcctcc tcctgtccca gcgagagcag   6240

gaaatagtgg tcctgcagca gcaactgcag gaagccaggg aacaagggga gctgaaggag   6300

cagtcacttc agagtcaact ggatgaggcc cagagagccc tagcccagag ggaccaggaa   6360

ctggaggctc tgcagcaaga acagcagcag gcccagggac aggaggagag ggtgaaggaa   6420

aaggcagacg ccctccaggg agctctggag caagcccata tgacactgaa ggagcgtcat   6480

ggagagcttc aggaccacaa ggaacaggca cgaaggctgg aggaagagct ggcagtggag   6540

ggacggcggg tccaggccct ggaggaggtg ctgggagacc taagggctga gtctcgggaa   6600

caggagaaag ctctgttggc cctccagcag cagtgtgctg agcaggcaca ggagcatgag   6660

gtggagacca gggccctgca ggacagctgg ctgcaggccc aggcagtgct caaggaacgg   6720

gaccaggagc tggaagctct gcgggcagaa agtcagtcct cccggcatca ggaggaggct   6780

gcccgggccc gggctgaggc tctgcaggag gcccttggca aggctcatgc tgccctgcag   6840

gggaaagagc agcatctcct cgagcaggca gaattgagcc gcagtctgga ggccagcact   6900

gcaaccctgc aagcctccct ggatgcctgc caggcacaca gtcggcagct ggaggaggct   6960

ctgaggatac aagaaggtga gatccaggac caggatctcc gataccagga ggatgtgcag   7020

cagctgcagc aggcacttgc ccagagggat gaagagctga gacatcagca ggaacgggag   7080

cagctgctgg agaagtctct ggcccagagg gtccaagaga atatgatcca agagaagcag   7140

aatctggggc aagagagaga agaggaggag ataaggggcc ttcatcagag tgtaagggag   7200

ctacagctga ctctagccca aaaggaacag gagattctgg agctgaggga gacccagcaa   7260

aggaacaacc tggaagcctt accccacagc cacaaaacct ccccaatgga ggaacaatct   7320

ctaaaacttg attctttaga gcccaggctg cagcgggagc tggagcggct acaggcagcc   7380

ctgagacaga cagaagccag ggagattgag tggagggaga aggcccagga cttggcactc   7440

tccctagcgc agaccaaggc cagtgtcagc agtctgcagg aggtagccat gttcctacaa   7500

gcctctgtcc tggagcggga ctcagaacag caaaggctgc aggatgaact ggagctcacc   7560

agacgggctc tggagaagga gcggctacac agcccaggtg caaccagcac agcagaactg   7620

gggtccagag gggagcaggg tgtgcagctg ggagaggtct caggagtgga ggctgagcct   7680

agtcctgatg gaatggagaa gcagtcatgg agacaaaggc ttgaacacct gcagcaagca   7740

gtggcccggc tggagattga caggagcagg ctgcagcgcc acaatgtcca gctgcggagt   7800

accttggagc aggtggagcg agaacggagg aagctgaaga gggaggccat gcgtgcggcc   7860

caggcagggt ccctagagat cagcaaggcc acggcttctt cacccacaca gcaggatggg   7920

agaggacaga agaactcaga tgccaagtgt gtggctgaac tgcagaaaga ggtggtcctg   7980

ctgcaagctc agctgacttt ggagcggaag cagaagcagg actacatcac ccgctcagca   8040

cagaccagcc gtgagctagc aggcctgcac cacagcctct cacactcact tcttgccgtg   8100

gcccaggccc ctgaggccac tgtcctggag gcagagaccc gcaggctgga tgagtccctg   8160

actcaaagtc tgacatcccc agggccagtc ctgctacacc ccagccccag cactacccaa   8220

gccgcctcca ggtagcagcc acagccagga gcacacagac agaagactgt gtcatgggtc   8280

atggcccctc cgcacaccta caggtttgcc aaaggaaaag cctggctctg ttaggcaccc   8340

aggagcccca ggtcggcggg tgttcccagg aagaggaagt aaatctgcaa ccctggggag   8400

gaccccaact cacctgggaa tgaggcaaat tgcatttgct tgctccctat ggaatcaccc   8460

agaggggtgc cttgccctgg ctgagggaca tgtactgcct ctcatctaga atttattttc   8520

ctagcacttc accacctcct tcatcttctc cttcaacaat aaaccctgag atctttgcat   8580

tcat                                                                8584


<210>  9580
<211>  2442
<212>  PRT
<213>  Homo sapiens

<400>  9580

Met Glu Thr Arg Ser Pro Gly Leu Asn Asn Met Lys Pro Gln Ser Leu 
1               5                   10                  15


Gln Leu Val Leu Glu Glu Gln Val Leu Ala Leu Gln Gln Gln Met Ala 
            20                  25                  30


Glu Asn Gln Ala Ala Ser Trp Arg Lys Leu Lys Asn Ser Gln Glu Ala 
        35                  40                  45


Gln Gln Arg Gln Ala Thr Leu Val Arg Lys Leu Gln Ala Lys Val Leu 
    50                  55                  60


Gln Tyr Arg Ser Trp Cys Gln Glu Leu Glu Lys Arg Leu Glu Ala Thr 
65                  70                  75                  80


Gly Gly Pro Ile Pro Gln Arg Trp Glu Asn Val Glu Glu Pro Asn Leu 
                85                  90                  95


Asp Glu Leu Leu Val Arg Leu Glu Glu Glu Gln Gln Arg Cys Glu Ser 
            100                 105                 110


Leu Ala Glu Val Asn Thr Gln Leu Arg Leu His Met Glu Lys Ala Asp 
        115                 120                 125


Val Val Asn Lys Ala Leu Arg Glu Asp Val Glu Lys Leu Thr Val Asp 
    130                 135                 140


Trp Ser Arg Ala Arg Asp Glu Leu Met Arg Lys Glu Ser Gln Trp Gln 
145                 150                 155                 160


Met Glu Gln Glu Phe Phe Lys Gly Tyr Leu Lys Gly Glu His Gly Arg 
                165                 170                 175


Leu Leu Ser Leu Trp Arg Glu Val Val Thr Phe Arg Arg His Phe Leu 
            180                 185                 190


Glu Met Lys Ser Ala Thr Asp Arg Asp Leu Met Glu Leu Lys Ala Glu 
        195                 200                 205


His Val Arg Leu Ser Gly Ser Leu Leu Thr Cys Cys Leu Arg Leu Thr 
    210                 215                 220


Val Gly Ala Gln Ser Arg Glu Pro Asn Gly Ser Gly Arg Met Asp Gly 
225                 230                 235                 240


Arg Glu Pro Ala Gln Leu Leu Leu Leu Leu Ala Lys Thr Gln Glu Leu 
                245                 250                 255


Glu Lys Glu Ala His Glu Arg Ser Gln Glu Leu Ile Gln Leu Lys Ser 
            260                 265                 270


Gln Gly Asp Leu Glu Lys Ala Glu Leu Gln Asp Arg Val Thr Glu Leu 
        275                 280                 285


Ser Ala Leu Leu Thr Gln Ser Gln Lys Gln Asn Glu Asp Tyr Glu Lys 
    290                 295                 300


Met Ile Lys Ala Leu Arg Glu Thr Val Glu Ile Leu Glu Thr Asn His 
305                 310                 315                 320


Thr Glu Leu Met Glu His Glu Ala Ser Leu Ser Arg Asn Ala Gln Glu 
                325                 330                 335


Glu Lys Leu Ser Leu Gln Gln Val Ile Lys Asp Ile Thr Gln Val Met 
            340                 345                 350


Val Glu Glu Gly Asp Asn Ile Ala Gln Gly Ser Gly His Glu Asn Ser 
        355                 360                 365


Leu Glu Leu Asp Ser Ser Ile Phe Ser Gln Phe Asp Tyr Gln Asp Ala 
    370                 375                 380


Asp Lys Ala Leu Thr Leu Val Arg Ser Val Leu Thr Arg Arg Arg Gln 
385                 390                 395                 400


Ala Val Gln Asp Leu Arg Gln Gln Leu Ala Gly Cys Gln Glu Ala Val 
                405                 410                 415


Asn Leu Leu Gln Gln Gln His Asp Gln Trp Glu Glu Glu Gly Lys Ala 
            420                 425                 430


Leu Arg Gln Arg Leu Gln Lys Leu Thr Gly Glu Arg Asp Thr Leu Ala 
        435                 440                 445


Gly Gln Thr Val Asp Leu Gln Gly Glu Val Asp Ser Leu Ser Lys Glu 
    450                 455                 460


Arg Glu Leu Leu Gln Lys Ala Arg Glu Glu Leu Arg Gln Gln Leu Glu 
465                 470                 475                 480


Val Leu Glu Gln Glu Ala Trp Arg Leu Arg Arg Val Asn Val Glu Leu 
                485                 490                 495


Gln Leu Gln Gly Asp Ser Ala Gln Gly Gln Lys Glu Glu Gln Gln Glu 
            500                 505                 510


Glu Leu His Leu Ala Val Arg Glu Arg Glu Arg Leu Gln Glu Met Leu 
        515                 520                 525


Met Gly Leu Glu Ala Lys Gln Ser Glu Ser Leu Ser Glu Leu Ile Thr 
    530                 535                 540


Leu Arg Glu Ala Leu Glu Ser Ser His Leu Glu Gly Glu Leu Leu Arg 
545                 550                 555                 560


Gln Glu Gln Thr Glu Val Thr Ala Ala Leu Ala Arg Ala Glu Gln Ser 
                565                 570                 575


Ile Ala Glu Leu Ser Ser Ser Glu Asn Thr Leu Lys Thr Glu Val Ala 
            580                 585                 590


Asp Leu Arg Ala Ala Ala Val Lys Leu Ser Ala Leu Asn Glu Ala Leu 
        595                 600                 605


Ala Leu Asp Lys Val Gly Leu Asn Gln Gln Leu Leu Gln Leu Glu Glu 
    610                 615                 620


Glu Asn Gln Ser Val Cys Ser Arg Met Glu Ala Ala Glu Gln Ala Arg 
625                 630                 635                 640


Asn Ala Leu Gln Val Asp Leu Ala Glu Ala Glu Lys Arg Arg Glu Ala 
                645                 650                 655


Leu Trp Glu Lys Asn Thr His Leu Glu Ala Gln Leu Gln Lys Ala Glu 
            660                 665                 670


Glu Ala Gly Ala Glu Leu Gln Ala Asp Leu Arg Asp Ile Gln Glu Glu 
        675                 680                 685


Lys Glu Glu Ile Gln Lys Lys Leu Ser Glu Ser Arg His Gln Gln Glu 
    690                 695                 700


Ala Ala Thr Thr Gln Leu Glu Gln Leu His Gln Glu Ala Lys Arg Gln 
705                 710                 715                 720


Glu Glu Val Leu Ala Arg Ala Val Gln Glu Lys Glu Ala Leu Val Arg 
                725                 730                 735


Glu Lys Ala Ala Leu Glu Val Arg Leu Gln Ala Val Glu Arg Asp Arg 
            740                 745                 750


Gln Asp Leu Ala Glu Gln Leu Gln Gly Leu Ser Ser Ala Lys Glu Leu 
        755                 760                 765


Leu Glu Ser Ser Leu Phe Glu Ala Gln Gln Gln Asn Ser Val Ile Glu 
    770                 775                 780


Val Thr Lys Gly Gln Leu Glu Val Gln Ile Gln Thr Val Thr Gln Ala 
785                 790                 795                 800


Lys Glu Val Ile Gln Gly Glu Val Arg Cys Leu Lys Leu Glu Leu Asp 
                805                 810                 815


Thr Glu Arg Ser Gln Ala Glu Gln Glu Arg Asp Ala Ala Ala Arg Gln 
            820                 825                 830


Leu Ala Gln Ala Glu Gln Glu Gly Lys Thr Ala Leu Glu Gln Gln Lys 
        835                 840                 845


Ala Ala His Glu Lys Glu Val Asn Gln Leu Arg Glu Lys Trp Glu Lys 
    850                 855                 860


Glu Arg Ser Trp His Gln Gln Glu Leu Ala Lys Ala Leu Glu Ser Leu 
865                 870                 875                 880


Glu Arg Glu Lys Met Glu Leu Glu Met Arg Leu Lys Glu Gln Gln Thr 
                885                 890                 895


Glu Met Glu Ala Ile Gln Ala Gln Arg Glu Glu Glu Arg Thr Gln Ala 
            900                 905                 910


Glu Ser Ala Leu Cys Gln Met Gln Leu Glu Thr Glu Lys Glu Arg Val 
        915                 920                 925


Ser Leu Leu Glu Thr Leu Leu Gln Thr Gln Lys Glu Leu Ala Asp Ala 
    930                 935                 940


Ser Gln Gln Leu Glu Arg Leu Arg Gln Asp Met Lys Val Gln Lys Leu 
945                 950                 955                 960


Lys Glu Gln Glu Thr Thr Gly Ile Leu Gln Thr Gln Leu Gln Glu Ala 
                965                 970                 975


Gln Arg Glu Leu Lys Glu Ala Ala Arg Gln His Arg Asp Asp Leu Ala 
            980                 985                 990


Ala Leu Gln Glu Glu Ser Ser Ser Leu Leu Gln Asp Lys Met Asp Leu 
        995                 1000                1005


Gln Lys Gln Val Glu Asp Leu Lys Ser Gln Leu Val Ala Gln Asp Asp 
    1010                1015                1020


Ser Gln Arg Leu Val Glu Gln Glu Val Gln Glu Lys Leu Arg Glu Thr 
1025                1030                1035                1040


Gln Glu Tyr Asn Arg Ile Gln Lys Glu Leu Glu Arg Glu Lys Ala Ser 
                1045                1050                1055


Leu Thr Leu Ser Leu Met Glu Lys Glu Gln Arg Leu Leu Val Leu Gln 
            1060                1065                1070


Glu Ala Asp Ser Ile Arg Gln Gln Glu Leu Ser Ala Leu Arg Gln Asp 
        1075                1080                1085


Met Gln Glu Ala Gln Gly Glu Gln Lys Glu Leu Ser Ala Gln Met Glu 
    1090                1095                1100


Leu Leu Arg Gln Glu Val Lys Glu Lys Glu Ala Asp Phe Leu Ala Gln 
1105                1110                1115                1120


Glu Ala Gln Leu Leu Glu Glu Leu Glu Ala Ser His Ile Thr Glu Gln 
                1125                1130                1135


Gln Leu Arg Ala Ser Leu Trp Ala Gln Glu Ala Lys Ala Ala Gln Leu 
            1140                1145                1150


Gln Leu Arg Leu Arg Ser Thr Glu Ser Gln Leu Glu Ala Leu Ala Ala 
        1155                1160                1165


Glu Gln Gln Pro Gly Asn Gln Ala Gln Ala Gln Ala Gln Leu Ala Ser 
    1170                1175                1180


Leu Tyr Ser Ala Leu Gln Gln Ala Leu Gly Ser Val Cys Glu Ser Arg 
1185                1190                1195                1200


Pro Glu Leu Ser Gly Gly Gly Asp Ser Ala Pro Ser Val Trp Gly Leu 
                1205                1210                1215


Glu Pro Asp Gln Asn Gly Ala Arg Ser Leu Phe Lys Arg Gly Pro Leu 
            1220                1225                1230


Leu Thr Ala Leu Ser Ala Glu Ala Val Ala Ser Ala Leu His Lys Leu 
        1235                1240                1245


His Gln Asp Leu Trp Lys Thr Gln Gln Thr Arg Asp Val Leu Arg Asp 
    1250                1255                1260


Gln Val Gln Lys Leu Glu Glu Arg Leu Thr Asp Thr Glu Ala Glu Lys 
1265                1270                1275                1280


Ser Gln Val His Thr Glu Leu Gln Asp Leu Gln Arg Gln Leu Ser Gln 
                1285                1290                1295


Asn Gln Glu Glu Lys Ser Lys Trp Glu Gly Lys Gln Asn Ser Leu Glu 
            1300                1305                1310


Ser Glu Leu Met Glu Leu His Glu Thr Met Ala Ser Leu Gln Ser Arg 
        1315                1320                1325


Leu Arg Arg Ala Glu Leu Gln Arg Met Glu Ala Gln Gly Glu Arg Glu 
    1330                1335                1340


Leu Leu Gln Ala Ala Lys Glu Asn Leu Thr Ala Gln Val Glu His Leu 
1345                1350                1355                1360


Gln Ala Ala Val Val Glu Ala Arg Ala Gln Ala Ser Ala Ala Gly Ile 
                1365                1370                1375


Leu Glu Glu Asp Leu Arg Thr Ala Arg Ser Ala Leu Lys Leu Lys Asn 
            1380                1385                1390


Glu Glu Val Glu Ser Glu Arg Glu Arg Ala Gln Ala Leu Gln Glu Gln 
        1395                1400                1405


Gly Glu Leu Lys Val Ala Gln Gly Lys Ala Leu Gln Glu Asn Leu Ala 
    1410                1415                1420


Leu Leu Thr Gln Thr Leu Ala Glu Arg Glu Glu Glu Val Glu Thr Leu 
1425                1430                1435                1440


Arg Gly Gln Ile Gln Glu Leu Glu Lys Gln Arg Glu Met Gln Lys Ala 
                1445                1450                1455


Ala Leu Glu Leu Leu Ser Leu Asp Leu Lys Lys Arg Asn Gln Glu Val 
            1460                1465                1470


Asp Leu Gln Gln Glu Gln Ile Gln Glu Leu Glu Lys Cys Arg Ser Val 
        1475                1480                1485


Leu Glu His Leu Pro Met Ala Val Gln Glu Arg Glu Gln Lys Leu Thr 
    1490                1495                1500


Val Gln Arg Glu Gln Ile Arg Glu Leu Glu Lys Asp Arg Glu Thr Gln 
1505                1510                1515                1520


Arg Asn Val Leu Glu His Gln Leu Leu Glu Leu Glu Lys Lys Asp Gln 
                1525                1530                1535


Met Ile Glu Ser Gln Arg Gly Gln Val Gln Asp Leu Lys Lys Gln Leu 
            1540                1545                1550


Val Thr Leu Glu Cys Leu Ala Leu Glu Leu Glu Glu Asn His His Lys 
        1555                1560                1565


Met Glu Cys Gln Gln Lys Leu Ile Lys Glu Leu Glu Gly Gln Arg Glu 
    1570                1575                1580


Thr Gln Arg Val Ala Leu Thr His Leu Thr Leu Asp Leu Glu Glu Arg 
1585                1590                1595                1600


Ser Gln Glu Leu Gln Ala Gln Ser Ser Gln Ile His Asp Leu Glu Ser 
                1605                1610                1615


His Ser Thr Val Leu Ala Arg Glu Leu Gln Glu Arg Asp Gln Glu Val 
            1620                1625                1630


Lys Ser Gln Arg Glu Gln Ile Glu Glu Leu Gln Arg Gln Lys Glu His 
        1635                1640                1645


Leu Thr Gln Asp Leu Glu Arg Arg Asp Gln Glu Leu Met Leu Gln Lys 
    1650                1655                1660


Glu Arg Ile Gln Val Leu Glu Asp Gln Arg Thr Arg Gln Thr Lys Ile 
1665                1670                1675                1680


Leu Glu Glu Asp Leu Glu Gln Ile Lys Leu Ser Leu Arg Glu Arg Gly 
                1685                1690                1695


Arg Glu Leu Thr Thr Gln Arg Gln Leu Met Gln Glu Arg Ala Glu Glu 
            1700                1705                1710


Gly Lys Gly Pro Ser Lys Ala Gln Arg Gly Ser Leu Glu His Met Lys 
        1715                1720                1725


Leu Ile Leu Arg Asp Lys Glu Lys Glu Val Glu Cys Gln Gln Glu His 
    1730                1735                1740


Ile His Glu Leu Gln Glu Leu Lys Asp Gln Leu Glu Gln Gln Leu Gln 
1745                1750                1755                1760


Gly Leu His Arg Lys Val Gly Glu Thr Ser Leu Leu Leu Ser Gln Arg 
                1765                1770                1775


Glu Gln Glu Ile Val Val Leu Gln Gln Gln Leu Gln Glu Ala Arg Glu 
            1780                1785                1790


Gln Gly Glu Leu Lys Glu Gln Ser Leu Gln Ser Gln Leu Asp Glu Ala 
        1795                1800                1805


Gln Arg Ala Leu Ala Gln Arg Asp Gln Glu Leu Glu Ala Leu Gln Gln 
    1810                1815                1820


Glu Gln Gln Gln Ala Gln Gly Gln Glu Glu Arg Val Lys Glu Lys Ala 
1825                1830                1835                1840


Asp Ala Leu Gln Gly Ala Leu Glu Gln Ala His Met Thr Leu Lys Glu 
                1845                1850                1855


Arg His Gly Glu Leu Gln Asp His Lys Glu Gln Ala Arg Arg Leu Glu 
            1860                1865                1870


Glu Glu Leu Ala Val Glu Gly Arg Arg Val Gln Ala Leu Glu Glu Val 
        1875                1880                1885


Leu Gly Asp Leu Arg Ala Glu Ser Arg Glu Gln Glu Lys Ala Leu Leu 
    1890                1895                1900


Ala Leu Gln Gln Gln Cys Ala Glu Gln Ala Gln Glu His Glu Val Glu 
1905                1910                1915                1920


Thr Arg Ala Leu Gln Asp Ser Trp Leu Gln Ala Gln Ala Val Leu Lys 
                1925                1930                1935


Glu Arg Asp Gln Glu Leu Glu Ala Leu Arg Ala Glu Ser Gln Ser Ser 
            1940                1945                1950


Arg His Gln Glu Glu Ala Ala Arg Ala Arg Ala Glu Ala Leu Gln Glu 
        1955                1960                1965


Ala Leu Gly Lys Ala His Ala Ala Leu Gln Gly Lys Glu Gln His Leu 
    1970                1975                1980


Leu Glu Gln Ala Glu Leu Ser Arg Ser Leu Glu Ala Ser Thr Ala Thr 
1985                1990                1995                2000


Leu Gln Ala Ser Leu Asp Ala Cys Gln Ala His Ser Arg Gln Leu Glu 
                2005                2010                2015


Glu Ala Leu Arg Ile Gln Glu Gly Glu Ile Gln Asp Gln Asp Leu Arg 
            2020                2025                2030


Tyr Gln Glu Asp Val Gln Gln Leu Gln Gln Ala Leu Ala Gln Arg Asp 
        2035                2040                2045


Glu Glu Leu Arg His Gln Gln Glu Arg Glu Gln Leu Leu Glu Lys Ser 
    2050                2055                2060


Leu Ala Gln Arg Val Gln Glu Asn Met Ile Gln Glu Lys Gln Asn Leu 
2065                2070                2075                2080


Gly Gln Glu Arg Glu Glu Glu Glu Ile Arg Gly Leu His Gln Ser Val 
                2085                2090                2095


Arg Glu Leu Gln Leu Thr Leu Ala Gln Lys Glu Gln Glu Ile Leu Glu 
            2100                2105                2110


Leu Arg Glu Thr Gln Gln Arg Asn Asn Leu Glu Ala Leu Pro His Ser 
        2115                2120                2125


His Lys Thr Ser Pro Met Glu Glu Gln Ser Leu Lys Leu Asp Ser Leu 
    2130                2135                2140


Glu Pro Arg Leu Gln Arg Glu Leu Glu Arg Leu Gln Ala Ala Leu Arg 
2145                2150                2155                2160


Gln Thr Glu Ala Arg Glu Ile Glu Trp Arg Glu Lys Ala Gln Asp Leu 
                2165                2170                2175


Ala Leu Ser Leu Ala Gln Thr Lys Ala Ser Val Ser Ser Leu Gln Glu 
            2180                2185                2190


Val Ala Met Phe Leu Gln Ala Ser Val Leu Glu Arg Asp Ser Glu Gln 
        2195                2200                2205


Gln Arg Leu Gln Asp Glu Leu Glu Leu Thr Arg Arg Ala Leu Glu Lys 
    2210                2215                2220


Glu Arg Leu His Ser Pro Gly Ala Thr Ser Thr Ala Glu Leu Gly Ser 
2225                2230                2235                2240


Arg Gly Glu Gln Gly Val Gln Leu Gly Glu Val Ser Gly Val Glu Ala 
                2245                2250                2255


Glu Pro Ser Pro Asp Gly Met Glu Lys Gln Ser Trp Arg Gln Arg Leu 
            2260                2265                2270


Glu His Leu Gln Gln Ala Val Ala Arg Leu Glu Ile Asp Arg Ser Arg 
        2275                2280                2285


Leu Gln Arg His Asn Val Gln Leu Arg Ser Thr Leu Glu Gln Val Glu 
    2290                2295                2300


Arg Glu Arg Arg Lys Leu Lys Arg Glu Ala Met Arg Ala Ala Gln Ala 
2305                2310                2315                2320


Gly Ser Leu Glu Ile Ser Lys Ala Thr Ala Ser Ser Pro Thr Gln Gln 
                2325                2330                2335


Asp Gly Arg Gly Gln Lys Asn Ser Asp Ala Lys Cys Val Ala Glu Leu 
            2340                2345                2350


Gln Lys Glu Val Val Leu Leu Gln Ala Gln Leu Thr Leu Glu Arg Lys 
        2355                2360                2365


Gln Lys Gln Asp Tyr Ile Thr Arg Ser Ala Gln Thr Ser Arg Glu Leu 
    2370                2375                2380


Ala Gly Leu His His Ser Leu Ser His Ser Leu Leu Ala Val Ala Gln 
2385                2390                2395                2400


Ala Pro Glu Ala Thr Val Leu Glu Ala Glu Thr Arg Arg Leu Asp Glu 
                2405                2410                2415


Ser Leu Thr Gln Ser Leu Thr Ser Pro Gly Pro Val Leu Leu His Pro 
            2420                2425                2430


Ser Pro Ser Thr Thr Gln Ala Ala Ser Arg 
        2435                2440


<210>  9581
<211>  1243
<212>  DNA
<213>  Homo sapiens

<400>  9581
ggcgaactga aggtggccca agggaaggct ctgcaagaga atttggccct cctgacccag     60

accctagctg aaagagaaga ggaggtggag actctgcggg gacaaatcca ggaactggag    120

aagcaacggg aaatgcagaa ggctgctttg gaattgctgt ctctggacct gaagaagagg    180

aaccaagagg tagatctgca gcaagaacag attcaggagc tagagaagtg taggtctgtt    240

ttagagcatc tgcccatggc cgtccaggag cgagagcaga agctgactgt gcagagggag    300

cagatcagag agctcgagaa ggatcgggag actcagagga acgtcttgga gcatcagctt    360

ctagaacttg agaagaaaga ccaaatgatt gagtcccaga gaggacaggt tcaggacctg    420

aaaaagcagt tggttactct ggaatgcctg gccctggaac tggaggaaaa ccatcacaag    480

atggagtgcc agcaaaaact gatcaaggag ctggagggcc agagggaaac ccagagagtg    540

gctttgaccc accttacgct ggacctagaa gaaaggagcc aggagctgca ggcacaaagc    600

agccagatcc atgacctgga gagccacagc accgttctgg caagagagct gcaggagagg    660

gaccaggagg tgaagtctca gcgagaacag atcgaggagc tgcctccctc tggacctatt    720

cagtcctcaa gggtgccctg ctaaaggctg ggctgaaagc taagaggaga ggtggcattc    780

aatgtgtcct gtgtcctccc tggggttgat taaggggtcg atgcccaata gagtccttca    840

tcttggcgtt cagcccaggg tccagctgcc aagggaaggc ttggcaatca agggtgatgg    900

agataagaat gaaaaggggc accaccctgt gccaaagctg gcatgttgta tatctgagag    960

aggagctgcc tattcacagt gtagggttgt caagctggag gcagggagag aaaagcaaga   1020

gctttttggt tcctcttgag gatagaatct ataggaaaat gtaagagggt taaaaataaa   1080

tttcccatgc atccaaactt ttttctttgg tagactttct tgtcatctat ttaaaatgaa   1140

acaagtgcat gtacgtggtt aagacatttt agctaggaat gatggtgcgt gcctgtagtc   1200

ccagctactt gggaggctga ggcaggagga tcgcttgaac ctg                     1243


<210>  9582
<211>  203
<212>  PRT
<213>  Homo sapiens

<400>  9582

Met Gln Lys Ala Ala Leu Glu Leu Leu Ser Leu Asp Leu Lys Lys Arg 
1               5                   10                  15


Asn Gln Glu Val Asp Leu Gln Gln Glu Gln Ile Gln Glu Leu Glu Lys 
            20                  25                  30


Cys Arg Ser Val Leu Glu His Leu Pro Met Ala Val Gln Glu Arg Glu 
        35                  40                  45


Gln Lys Leu Thr Val Gln Arg Glu Gln Ile Arg Glu Leu Glu Lys Asp 
    50                  55                  60


Arg Glu Thr Gln Arg Asn Val Leu Glu His Gln Leu Leu Glu Leu Glu 
65                  70                  75                  80


Lys Lys Asp Gln Met Ile Glu Ser Gln Arg Gly Gln Val Gln Asp Leu 
                85                  90                  95


Lys Lys Gln Leu Val Thr Leu Glu Cys Leu Ala Leu Glu Leu Glu Glu 
            100                 105                 110


Asn His His Lys Met Glu Cys Gln Gln Lys Leu Ile Lys Glu Leu Glu 
        115                 120                 125


Gly Gln Arg Glu Thr Gln Arg Val Ala Leu Thr His Leu Thr Leu Asp 
    130                 135                 140


Leu Glu Glu Arg Ser Gln Glu Leu Gln Ala Gln Ser Ser Gln Ile His 
145                 150                 155                 160


Asp Leu Glu Ser His Ser Thr Val Leu Ala Arg Glu Leu Gln Glu Arg 
                165                 170                 175


Asp Gln Glu Val Lys Ser Gln Arg Glu Gln Ile Glu Glu Leu Pro Pro 
            180                 185                 190


Ser Gly Pro Ile Gln Ser Ser Arg Val Pro Cys 
        195                 200


<210>  9583
<211>  496
<212>  DNA
<213>  Homo sapiens

<400>  9583
aggtatatcc aggaaagttg gctggagaac catggtcagt atccgtcctt ggagtttgtg     60

gctctgttgt atgccttgca tacctgtgac caggtatcct tgtttggttt tggggaagac    120

aattgcaaaa ggtggtccca ttactgggat gacaaatatt ggtttgagaa caccatgcaa    180

aatttcccag cagaatacca gatcatcttg aaactgcagt gtgagaggaa gattgctgtc    240

tacggctgag atgtttccag tggagtcccc aggaggcttg acaggtagcc aaggggacct    300

tgtggtgtca gagagggact agggcttcaa gcagaccctg gatggagatt actctgctac    360

tgaataaaac cctagcttat ttctctctct ggatttctgg tggcattaaa gggctacatt    420

ctattactga ttctgtctta tcaccatgtg actctcttat gctgtatctt accaaaaaat    480

aaaattaaat gagaaa                                                    496


<210>  9584
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  9584

Met Val Ser Ile Arg Pro Trp Ser Leu Trp Leu Cys Cys Met Pro Cys 
1               5                   10                  15


Ile Pro Val Thr Arg Tyr Pro Cys Leu Val Leu Gly Lys Thr Ile Ala 
            20                  25                  30


Lys Gly Gly Pro Ile Thr Gly Met Thr Asn Ile Gly Leu Arg Thr Pro 
        35                  40                  45


Cys Lys Ile Ser Gln Gln Asn Thr Arg Ser Ser 
    50                  55


<210>  9585
<211>  870
<212>  DNA
<213>  Homo sapiens

<400>  9585
atgctgggga cttctgtggc cccagcctct tcttcccggt gccaggtgtc ggggccaatc     60

tactgtctgc caggggcacc atcatcaggg ccagagatca tgattcgata caggagtttg    120

ggcctggtgg ctgcctatgt cctttcattg tggctgatca cctccttcct acaccagcac    180

tccagccaga aggacctccg taatatggcc aagatacacc caggaatctg ccaccatccc    240

agcaactttt ccagaaaatg caactgctca tctgaggtcc acacatgctc tgcctgcctc    300

cacgtgcctg gcgagtctga ctggtttgac agacgcttcg acagtaccgt tgaaccccta    360

cagaggccac aagatcccac gtccaatgat gctctgatat tgtggctggg actcgagagg    420

gtcaagtcag agaaggaggt tgagaataag cagcagcagc tgattaaagc acctcccctg    480

tgcccactgg gccatgtggt gtccaactgc cgggtctgtg cagtggtggg aaactcaagg    540

tctctatgga gctctggcct tggcttcagg attaatcaac atgaagtggt cctcaggatg    600

aaccaggccc ctgtctgagg ctttgaggca gatgtgggga acaggaccac catgcgcgtt    660

atgtaccctg ggattgccag ccctcaggac cccggtaccc aactgctgct gcttccgttg    720

aattcatctg gtctggagtg gttcataagt gtactgcata aacagacaag catgtggaag    780

caaaaaaaac cctggatttc agacggttca ggttcctggt ggaaccgaag acagcaaaga    840

taaggtgctg gtgatcagcc tctacttcct                                     870


<210>  9586
<211>  205
<212>  PRT
<213>  Homo sapiens

<400>  9586

Met Leu Gly Thr Ser Val Ala Pro Ala Ser Ser Ser Arg Cys Gln Val 
1               5                   10                  15


Ser Gly Pro Ile Tyr Cys Leu Pro Gly Ala Pro Ser Ser Gly Pro Glu 
            20                  25                  30


Ile Met Ile Arg Tyr Arg Ser Leu Gly Leu Val Ala Ala Tyr Val Leu 
        35                  40                  45


Ser Leu Trp Leu Ile Thr Ser Phe Leu His Gln His Ser Ser Gln Lys 
    50                  55                  60


Asp Leu Arg Asn Met Ala Lys Ile His Pro Gly Ile Cys His His Pro 
65                  70                  75                  80


Ser Asn Phe Ser Arg Lys Cys Asn Cys Ser Ser Glu Val His Thr Cys 
                85                  90                  95


Ser Ala Cys Leu His Val Pro Gly Glu Ser Asp Trp Phe Asp Arg Arg 
            100                 105                 110


Phe Asp Ser Thr Val Glu Pro Leu Gln Arg Pro Gln Asp Pro Thr Ser 
        115                 120                 125


Asn Asp Ala Leu Ile Leu Trp Leu Gly Leu Glu Arg Val Lys Ser Glu 
    130                 135                 140


Lys Glu Val Glu Asn Lys Gln Gln Gln Leu Ile Lys Ala Pro Pro Leu 
145                 150                 155                 160


Cys Pro Leu Gly His Val Val Ser Asn Cys Arg Val Cys Ala Val Val 
                165                 170                 175


Gly Asn Ser Arg Ser Leu Trp Ser Ser Gly Leu Gly Phe Arg Ile Asn 
            180                 185                 190


Gln His Glu Val Val Leu Arg Met Asn Gln Ala Pro Val 
        195                 200                 205


<210>  9587
<211>  1034
<212>  DNA
<213>  Homo sapiens

<400>  9587
acatgctgtc tctctgccct ggcctcttcc accccatgcc cagtcagaga ccgttttgag     60

gcattgcgac tgcccttggt tcagttccgg gaagtgtggc tgcccttctg agaccctcaa    120

ctgctcctcc tgccaccaca cagccgacga atggaactgg cttgatgcgt gctccaggaa    180

gactatgggg tacctgatga ggacaagaga gtctatgacc tctgacactg tgctctggtg    240

gttggtcagt ggtcaacact gggcccggcc atatccccca tgctttccgg gcctcaccca    300

tctcccactt tccgcccaaa tccctgccct tggccctgtc ttcacagcct ctggatggag    360

atctcaccca cccagctctg ttttctctcc cctgggccca gcccccaatc tccctcttgc    420

tgtttccagg gcatgaactc agggagcgag cttgggaaat tgtggaggaa gctgtttaaa    480

gggattccca ggctctcggt gagccatttt gatttctatt gtgggacttg tgtgctgttg    540

gggcgcccac agatcccgca gggctccagc cttggcaacg acatcgacca ataccccgtg    600

gttttcagga atgccagcga ccagggctcc tggatgcagc tggagatgct actgcggaag    660

ctctctgacc tggtgtggac ttcagatgct ctaagtgata agattttgga agatggtctg    720

gttccctagt ggagtggaag atagcaaaga cacggtcacc ctctttggat ttggatcaga    780

atagcaagga aagtgtttct atcactggaa ggaggataat cagaccaagg gctccaagga    840

aatactgccc acgtctagtg caggagcaga aatcgaagtc atccatcagc tagcgtgtgg    900

acaagctcac tattcacaca agctcagcct agctgagtcc atacaaatcc tatttctggg    960

tgggtaaagg gcaggaggaa attgtaagat cagtctggta ctgaataaaa tcctggcctg   1020

attgtcttac ctgt                                                     1034


<210>  9588
<211>  149
<212>  PRT
<213>  Homo sapiens

<400>  9588

Met Leu Ser Gly Pro His Pro Ser Pro Thr Phe Arg Pro Asn Pro Cys 
1               5                   10                  15


Pro Trp Pro Cys Leu His Ser Leu Trp Met Glu Ile Ser Pro Thr Gln 
            20                  25                  30


Leu Cys Phe Leu Ser Pro Gly Pro Ser Pro Gln Ser Pro Ser Cys Cys 
        35                  40                  45


Phe Gln Gly Met Asn Ser Gly Ser Glu Leu Gly Lys Leu Trp Arg Lys 
    50                  55                  60


Leu Phe Lys Gly Ile Pro Arg Leu Ser Val Ser His Phe Asp Phe Tyr 
65                  70                  75                  80


Cys Gly Thr Cys Val Leu Leu Gly Arg Pro Gln Ile Pro Gln Gly Ser 
                85                  90                  95


Ser Leu Gly Asn Asp Ile Asp Gln Tyr Pro Val Val Phe Arg Asn Ala 
            100                 105                 110


Ser Asp Gln Gly Ser Trp Met Gln Leu Glu Met Leu Leu Arg Lys Leu 
        115                 120                 125


Ser Asp Leu Val Trp Thr Ser Asp Ala Leu Ser Asp Lys Ile Leu Glu 
    130                 135                 140


Asp Gly Leu Val Pro 
145


<210>  9589
<211>  383
<212>  DNA
<213>  Homo sapiens

<400>  9589
agccacatgc tgtctctctg ccctggcctc ttccacccca tgcccagtca gagaccgttt     60

tgaggcattg cgactgccct tggttcagtt ccgggaagtg tggctgccct tctgagaccc    120

tcaactgctc ctcctgccac cacacagccg acgaatggaa ctggcttgat gcgtgctcca    180

ggaagactat ggggtacctg atgaggacaa gagagtctat gacctctgac actgtgctct    240

ggtggttggg catgaactca gggagcgagc ttgggaaatt gtggaggaag ctgtttaaag    300

ggattcccag gctctcggtg agccattttg atttctattg tgggacttgt gtgctgttgg    360

ggcgcccaca gatcccgcag ggc                                            383


<210>  9590
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  9590

Met Gly Tyr Leu Met Arg Thr Arg Glu Ser Met Thr Ser Asp Thr Val 
1               5                   10                  15


Leu Trp Trp Leu Gly Met Asn Ser Gly Ser Glu Leu Gly Lys Leu Trp 
            20                  25                  30


Arg Lys Leu Phe Lys Gly Ile Pro Arg Leu Ser Val Ser His Phe Asp 
        35                  40                  45


Phe Tyr Cys Gly Thr Cys Val Leu Leu Gly Arg Pro Gln Ile Pro Gln 
    50                  55                  60


<210>  9591
<211>  536
<212>  DNA
<213>  Homo sapiens

<400>  9591
actgaggtat tccttcccct ctcaggacta gccacatgct gtctctctgc cctggcctct     60

tccaccccat gcccagtcag agaccgtttt gagggtagag aagccagtct acggcccacc    120

acgggagcca ccgcctgggc cagacatgaa gcgctggcag atttttgtcc tgtgggtctt    180

ttgggtgctc atcctctggc tgatgacccc ctatctggat ctgacacctg aatcagcacc    240

ccaggaaaaa cgaatgtact tggtaccaca gcattgcgac tgcccttggt tcagttccgg    300

gaagtgtggc tgcccttctg agaccctcaa ctgctcctcc tgccaccaca cagccgacga    360

atggaactgg cttgatgcgt gctccaggaa gactatgggg tacctgatga ggacaagaga    420

gtctatgacc tctgacactg tgctctggtg gttgggcatg aactcaggga gcgagcttgg    480

gaaattgtgg aggaagctgt ttaaagggat tcccaggctc tcggtgagcc attttg        536


<210>  9592
<211>  129
<212>  PRT
<213>  Homo sapiens

<400>  9592

Met Lys Arg Trp Gln Ile Phe Val Leu Trp Val Phe Trp Val Leu Ile 
1               5                   10                  15


Leu Trp Leu Met Thr Pro Tyr Leu Asp Leu Thr Pro Glu Ser Ala Pro 
            20                  25                  30


Gln Glu Lys Arg Met Tyr Leu Val Pro Gln His Cys Asp Cys Pro Trp 
        35                  40                  45


Phe Ser Ser Gly Lys Cys Gly Cys Pro Ser Glu Thr Leu Asn Cys Ser 
    50                  55                  60


Ser Cys His His Thr Ala Asp Glu Trp Asn Trp Leu Asp Ala Cys Ser 
65                  70                  75                  80


Arg Lys Thr Met Gly Tyr Leu Met Arg Thr Arg Glu Ser Met Thr Ser 
                85                  90                  95


Asp Thr Val Leu Trp Trp Leu Gly Met Asn Ser Gly Ser Glu Leu Gly 
            100                 105                 110


Lys Leu Trp Arg Lys Leu Phe Lys Gly Ile Pro Arg Leu Ser Val Ser 
        115                 120                 125


His 



<210>  9593
<211>  789
<212>  DNA
<213>  Homo sapiens

<400>  9593
aggggggcgt ggctccaggc cggaagaggg agtctgtagg ggcgggccgg ctggcgtccc     60

ctttccggcc ggtccccatg gaggcgctgg ggaagctgaa gcagttcgat gcctacccca    120

agactttgga ggacttccgg gtcaagacct gcgggggcgc caccgtgacc attgtcagtg    180

gccttctcat gctgctactg ttcctgtccg agctgcagta ttacctcacc acggaggtgc    240

atcctgagct ctacgtggac aagtcgcggg gagataaact gaagatcaac atcgatgtac    300

tttttccgca catgccttgt gcctatctga gtattgatgc catggatgtg gccggagaac    360

agcagctgga tgtggaacac aacctgttca agcaacgact agataaagat ggcatccccg    420

tgagctcaga ggctgagcgg catgagcttg ggaaagtcga ggtgacggtg tttgaccctg    480

actccctgga ccctgatcgc tgtgagagct gctatggtgc tgaggcagaa gatatcaagt    540

gctgtaacac ctgtgaagat gtgcgggagg catatcgcct ggctggactc atcgattcgc    600

tcatctacca ctcagcacga gccatccaga agaaaattga tctagggaag acaacgtagt    660

caccctcggt gcttcctctg tctcctcttt ctccctggcc tgtggttgtc ccccagcctc    720

tgccaccctc cacctcctcg gtcagcccca gccccaggtt gataaatcta ttgattgatt    780

gtgatagta                                                            789


<210>  9594
<211>  193
<212>  PRT
<213>  Homo sapiens

<400>  9594

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Glu Leu Gly Lys Val Glu 
        115                 120                 125


Val Thr Val Phe Asp Pro Asp Ser Leu Asp Pro Asp Arg Cys Glu Ser 
    130                 135                 140


Cys Tyr Gly Ala Glu Ala Glu Asp Ile Lys Cys Cys Asn Thr Cys Glu 
145                 150                 155                 160


Asp Val Arg Glu Ala Tyr Arg Leu Ala Gly Leu Ile Asp Ser Leu Ile 
                165                 170                 175


Tyr His Ser Ala Arg Ala Ile Gln Lys Lys Ile Asp Leu Gly Lys Thr 
            180                 185                 190


Thr 



<210>  9595
<211>  1369
<212>  DNA
<213>  Homo sapiens

<400>  9595
gtggctccag gccggaagag ggagtctgta ggggcgggcc ggctggcgtc ccctttccgg     60

ccggtcccca tggaggcgct ggggaagctg aagcagttcg atgcctaccc caagactttg    120

gaggacttcc gggtcaagac ctgcgggggc gccaccgtga ccattgtcag tggccttctc    180

atgctgctac tgttcctgtc cgagctgcag tattacctca ccacggaggt gcatcctgag    240

ctctacgtgg acaagtcgcg gggagataaa ctgaagatca acatcgatgt actttttccg    300

cacatgcctt gtgcctatct gagtattgat gccatggatg tggccggaga acagcagctg    360

gatgtggaac acaacctgtt caagcaacga ctagataaag atggcatccc cgtgagctca    420

gaggctgagc ggcatgagct tgggaaagtc gaggtgacgg tgtttgaccc tgactccctg    480

gaccctgatc gctgtgagag ctgctatggt gctgaggcag aagatatcaa gtgctgtaac    540

acctgtgaag atgtgcggga ggcatatcgc cgtagaggct gggccttcaa gaacccagat    600

actattgagc agtgccggcg agagggcttc agccagaaga tgcaggagca gaagaatgaa    660

ggctgccagg tgtatggctt cttggaagtc aataaggtgg ccggaaactt ccactttgcc    720

cctgggaaga gcttccagca gtcccatgtg cacgtacatg ctgtggagat ccatgacttg    780

cagagctttg gccttgacaa catcaacatg acccactaca tccagcacct gtcatttggg    840

gaggactatc caggcattgt gaaccccctg gaccacacca atgtcactgc gccccaagcc    900

tccatgatgt tccagtactt tgtgaaggtg gtgcccactg tgtacatgaa ggtggacgga    960

gaggtactga ggacaaatca gttctctgtg accagacatg agaaggttgc caatgggctg   1020

ttgggcgacc aaggccttcc cggagtcttc gtcctctatg agctctcgcc catgatggtg   1080

aagctgacgg agaagcacag gtccttcacc cacttcctga caggtgtgtg cgccatcatt   1140

gggggcatgt tcacagtggc tggactcatc gattcgctca tctaccactc agcacgagcc   1200

atccagaaga aaattgatct agggaagaca acgtagtcac cctcggtgct tcctctgtct   1260

cctctttctc cctggcctgt ggttgtcccc cagcctctgc caccctccac ctcctcggtc   1320

agccccagcc ccaggttgat aaatctattg attgattgtg atagtactc               1369


<210>  9596
<211>  388
<212>  PRT
<213>  Homo sapiens

<400>  9596

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Glu Leu Gly Lys Val Glu 
        115                 120                 125


Val Thr Val Phe Asp Pro Asp Ser Leu Asp Pro Asp Arg Cys Glu Ser 
    130                 135                 140


Cys Tyr Gly Ala Glu Ala Glu Asp Ile Lys Cys Cys Asn Thr Cys Glu 
145                 150                 155                 160


Asp Val Arg Glu Ala Tyr Arg Arg Arg Gly Trp Ala Phe Lys Asn Pro 
                165                 170                 175


Asp Thr Ile Glu Gln Cys Arg Arg Glu Gly Phe Ser Gln Lys Met Gln 
            180                 185                 190


Glu Gln Lys Asn Glu Gly Cys Gln Val Tyr Gly Phe Leu Glu Val Asn 
        195                 200                 205


Lys Val Ala Gly Asn Phe His Phe Ala Pro Gly Lys Ser Phe Gln Gln 
    210                 215                 220


Ser His Val His Val His Ala Val Glu Ile His Asp Leu Gln Ser Phe 
225                 230                 235                 240


Gly Leu Asp Asn Ile Asn Met Thr His Tyr Ile Gln His Leu Ser Phe 
                245                 250                 255


Gly Glu Asp Tyr Pro Gly Ile Val Asn Pro Leu Asp His Thr Asn Val 
            260                 265                 270


Thr Ala Pro Gln Ala Ser Met Met Phe Gln Tyr Phe Val Lys Val Val 
        275                 280                 285


Pro Thr Val Tyr Met Lys Val Asp Gly Glu Val Leu Arg Thr Asn Gln 
    290                 295                 300


Phe Ser Val Thr Arg His Glu Lys Val Ala Asn Gly Leu Leu Gly Asp 
305                 310                 315                 320


Gln Gly Leu Pro Gly Val Phe Val Leu Tyr Glu Leu Ser Pro Met Met 
                325                 330                 335


Val Lys Leu Thr Glu Lys His Arg Ser Phe Thr His Phe Leu Thr Gly 
            340                 345                 350


Val Cys Ala Ile Ile Gly Gly Met Phe Thr Val Ala Gly Leu Ile Asp 
        355                 360                 365


Ser Leu Ile Tyr His Ser Ala Arg Ala Ile Gln Lys Lys Ile Asp Leu 
    370                 375                 380


Gly Lys Thr Thr 
385


<210>  9597
<211>  1355
<212>  DNA
<213>  Homo sapiens

<400>  9597
gtggctccag gccggaagag ggagtctgta ggggcgggcc ggctggcgtc ccctttccgg     60

ccggtcccca tggaggcgct ggggaagctg aagcagttcg atgcctaccc caagactttg    120

gaggacttcc gggtcaagac ctgcgggggc gccaccgtga ccattgtcag tggccttctc    180

atgctgctac tgttcctgtc cgagctgcag tattacctca ccacggaggt gcatcctgag    240

ctctacgtgg acaagtcgcg gggagataaa ctgaagatca acatcgatgt actttttccg    300

cacatgcctt gtgcctatct gagtattgat gccatggatg tggccggaga acagcagctg    360

gatgtggaac acaacctgtt caagcaacga ctagataaag atggcatccc cgtgagctca    420

gaggctgagc ggcatgagct tgggaaagtc gaggtgacgg tgtttgaccc tgactccctg    480

gaccctgatc gctgtgagag ctgctatggt gctgaggcag aagatatcaa gtgctgtaac    540

acctgtgaag atgtgcggga ggcatatcgc cgtagaggct gggccttcaa gaacccagat    600

actattgagc agtgccggcg agagggcttc agccagaaga tgcaggagca gaagaatgaa    660

ggctgccagg tgtatggctt cttggaagtc aataaggtgg ccggaaactt ccactttgcc    720

cctgggaaga gcttccagca gtcccatgtg cacgtccatg acttgcagag ctttggcctt    780

gacaacatca acatgaccca ctacatccag cacctgtcat ttggggagga ctatccaggc    840

attgtgaacc ccctggacca caccaatgtc actgcgcccc aagcctccat gatgttccag    900

tactttgtga aggtggtgcc cactgtgtac atgaaggtgg acggagaggt actgaggaca    960

aatcagttct ctgtgaccag acatgagaag gttgccaatg ggctgttggg cgaccaaggc   1020

cttcccggag tcttcgtcct ctatgagctc tcgcccatga tggtgaagct gacggagaag   1080

cacaggtcct tcacccactt cctgacaggt gtgtgcgcca tcattggggg catgttcaca   1140

gtggctggac tcatcgattc gctcatctac cactcagcac gagccatcca gaagaaaatt   1200

gatctaggga agacaacgta gtcaccctcg gtgcttcctc tgtctcctct ttctccctgg   1260

cctgtggttg tcccccagcc tctgccaccc tccacctcct cggtcagccc cagccccagg   1320

ttgataaatc tattgattga ttgtgatagt actca                              1355


<210>  9598
<211>  383
<212>  PRT
<213>  Homo sapiens

<400>  9598

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Glu Leu Gly Lys Val Glu 
        115                 120                 125


Val Thr Val Phe Asp Pro Asp Ser Leu Asp Pro Asp Arg Cys Glu Ser 
    130                 135                 140


Cys Tyr Gly Ala Glu Ala Glu Asp Ile Lys Cys Cys Asn Thr Cys Glu 
145                 150                 155                 160


Asp Val Arg Glu Ala Tyr Arg Arg Arg Gly Trp Ala Phe Lys Asn Pro 
                165                 170                 175


Asp Thr Ile Glu Gln Cys Arg Arg Glu Gly Phe Ser Gln Lys Met Gln 
            180                 185                 190


Glu Gln Lys Asn Glu Gly Cys Gln Val Tyr Gly Phe Leu Glu Val Asn 
        195                 200                 205


Lys Val Ala Gly Asn Phe His Phe Ala Pro Gly Lys Ser Phe Gln Gln 
    210                 215                 220


Ser His Val His Val His Asp Leu Gln Ser Phe Gly Leu Asp Asn Ile 
225                 230                 235                 240


Asn Met Thr His Tyr Ile Gln His Leu Ser Phe Gly Glu Asp Tyr Pro 
                245                 250                 255


Gly Ile Val Asn Pro Leu Asp His Thr Asn Val Thr Ala Pro Gln Ala 
            260                 265                 270


Ser Met Met Phe Gln Tyr Phe Val Lys Val Val Pro Thr Val Tyr Met 
        275                 280                 285


Lys Val Asp Gly Glu Val Leu Arg Thr Asn Gln Phe Ser Val Thr Arg 
    290                 295                 300


His Glu Lys Val Ala Asn Gly Leu Leu Gly Asp Gln Gly Leu Pro Gly 
305                 310                 315                 320


Val Phe Val Leu Tyr Glu Leu Ser Pro Met Met Val Lys Leu Thr Glu 
                325                 330                 335


Lys His Arg Ser Phe Thr His Phe Leu Thr Gly Val Cys Ala Ile Ile 
            340                 345                 350


Gly Gly Met Phe Thr Val Ala Gly Leu Ile Asp Ser Leu Ile Tyr His 
        355                 360                 365


Ser Ala Arg Ala Ile Gln Lys Lys Ile Asp Leu Gly Lys Thr Thr 
    370                 375                 380


<210>  9599
<211>  687
<212>  DNA
<213>  Homo sapiens

<400>  9599
tggctccagg ccggaagagg gagtctgtag gggcgggccg gctggcgtcc cctttccggc     60

cggtccccat ggaggcgctg gggaagctga agcagttcga tgcctacccc aagactttgg    120

aggacttccg ggtcaagacc tgcgggggcg ccaccgtgac cattgtcagt ggccttctca    180

tgctgctact gttcctgtcc gagctgcagt attacctcac cacggaggtg catcctgagc    240

tctacgtgga caagtcgcgg ggagataaac tgaagatcaa catcgatgta ctttttccgc    300

acatgccttg tgcctatctg agtattgatg ccatggatgt ggccggagaa cagcagctgg    360

atgtggaaca caacctgttc aagcaacgac tagataaaga tggcatcccc gtgagctcag    420

aggctgagcg gcatgcagat taatgcagga caccagtgga accaacataa tttgctatag    480

gactggatgt ggagtggagg agagcaaagt catggttgtt gattccaacg ctttcagcct    540

gagcaaatga atgacttgag atggagatga ctggaggaga aggttttttt ggtgggaggg    600

aggagtggct attggatatc cactgctgtg taacaaagta ctccaaaagt tagtagtttg    660

atacaataaa aatgtgtttt ttcagtt                                        687


<210>  9600
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  9600

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Ala Asp 
        115                 120


<210>  9601
<211>  1672
<212>  DNA
<213>  Homo sapiens

<400>  9601
tggctccagg ccggaagagg gagtctgtag gggcgggccg gctggcgtcc cctttccggc     60

cggtccccat ggaggcgctg gggaagctga agcagttcga tgcctacccc aagactttgg    120

aggacttccg ggtcaagacc tgcgggggcg ccaccgtgac cattgtcagt ggccttctca    180

tgctgctact gttcctgtcc gagctgcagt attacctcac cacggaggtg catcctgagc    240

tctacgtgga caagtcgcgg ggagataaac tgaagatcaa catcgatgta ctttttccgc    300

acatgccttg tgcctatctg agtattgatg ccatggatgt ggccggagaa cagcagctgg    360

atgtggaaca caacctgttc aagcaacgac tagataaaga tggcatcccc gtgagctcag    420

aggctgagcg gcatgagctt gggaaagtcg aggtgacggt gtttgaccct gactccctgg    480

accctgatcg ctgtgagagc tgctatggtg ctgaggcaga agatatcaag tgctgtaaca    540

cctgtgaaga tgtgcgggag gcatatcgcc gtagaggctg ggccttcaag aacccagata    600

ctattgagca gtgccggcga gagggcttca gccagaagat gcaggagcag aagaatgaag    660

gctgccaggt gtatggcttc ttggaagtca ataaggtggc cggaaacttc cactttgccc    720

ctgggaagag cttccagcag tcccatgtgc acggtgagtg atctgcacta gctggggaga    780

tttagatgct ggccaccttc ttggtgagct tgagtggtcc tcttctgcct gctgctcatt    840

tgtcttgggc aaccatttgg ccagagcagg ccttcatctc agggcagcag tttggcacag    900

tggctaagag cacaggccga ggagccagac tgcctgcatt cagataccag tttcagacct    960

tactggctgt gtgactttga gaaggtttct taatcttttt gactcctgtt ttctacttta   1020

taaaatgttg atgagggcac ttatctcaca gggtgtgtgt gcaggttaaa gatgatagca   1080

cggagcctgg cttgtggtag gtacttgttg aaatggtagc cccccgtgtc cgatgatgac   1140

ctgtgcatga ggctttggga gaagcagagc taggttggag cacaggttct gccacacctg   1200

ggctatgtca tatttgggcc ctatttagtt gcttcttctg taaaatgggg atgatgataa   1260

tagtacccac tcacagggct gttggggtga acaaatgaga tttattctca ttcatttgtt   1320

cattcatgca ttcacaaaat atttagtaat cacctactag tctagttgct aagggtacag   1380

tagtgaacaa tctgtgccct cagaacattc tagtaaagaa atagacaata agtatataaa   1440

atataaatag tccccaatta acaatggttc agcttgcaat ttttaacttc atgatgggta   1500

ttacatgcat ttttcactta acgatatttt ctttttcttt tttgagacag agtctcactc   1560

tgtcgcccag gctggagtgc agtggcatga tcttgactca ctgcaacctc cacctcctgg   1620

attcaagtga ttctcctacc tcagcctctt gagtagctgg gtgtacaggt gc           1672


<210>  9602
<211>  230
<212>  PRT
<213>  Homo sapiens

<400>  9602

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Glu Leu Gly Lys Val Glu 
        115                 120                 125


Val Thr Val Phe Asp Pro Asp Ser Leu Asp Pro Asp Arg Cys Glu Ser 
    130                 135                 140


Cys Tyr Gly Ala Glu Ala Glu Asp Ile Lys Cys Cys Asn Thr Cys Glu 
145                 150                 155                 160


Asp Val Arg Glu Ala Tyr Arg Arg Arg Gly Trp Ala Phe Lys Asn Pro 
                165                 170                 175


Asp Thr Ile Glu Gln Cys Arg Arg Glu Gly Phe Ser Gln Lys Met Gln 
            180                 185                 190


Glu Gln Lys Asn Glu Gly Cys Gln Val Tyr Gly Phe Leu Glu Val Asn 
        195                 200                 205


Lys Val Ala Gly Asn Phe His Phe Ala Pro Gly Lys Ser Phe Gln Gln 
    210                 215                 220


Ser His Val His Gly Glu 
225                 230


<210>  9603
<211>  1398
<212>  DNA
<213>  Homo sapiens

<400>  9603
tggctccagg ccggaagagg gagtctgtag gggcgggccg gctggcgtcc cctttccggc     60

cggtccccat ggaggcgctg gggaagctga agcagttcga tgcctacccc aagactttgg    120

aggacttccg ggtcaagacc tgcgggggcg ccaccgtgac cattgtcagt ggccttctca    180

tgctgctact gttcctgtcc gagctgcagt attacctcac cacggaggtg catcctgagc    240

tctacgtgga caagtcgcgg ggagataaac tgaagatcaa catcgatgta ctttttccgc    300

acatgccttg tgcctatctg agtattgatg ccatggatgt ggccggagaa cagcagctgg    360

atgtggaaca caacctgttc aagcaacgac tagataaaga tggcatcccc gtgagctcag    420

aggctgagcg gcatgagctt gggaaagtcg aggtgacggt gtttgaccct gactccctgg    480

accctgatcg ctgtgagagc tgctatggtg ctgaggcaga agatatcaag tgctgtaaca    540

cctgtgaaga tgtgcgggag gcatatcgcc gtagaggctg ggccttcaag aacccagata    600

ctattgagca gtgccggcga gagggcttca gccagaagat gcaggagcag aagaatgaag    660

gctgccaggt gtatggcttc ttggaagtca ataaggtggc cggaaacttc cactttgccc    720

ctgggaagag cttccagcag tcccatgtgc acgggtgtgt gtgcaggtta aagatgatag    780

cacggagcct ggcttgtgtc catgacttgc agagctttgg ccttgacaac atcaacatga    840

cccactacat ccagcacctg tcatttgggg aggactatcc aggcattgtg aaccccctgg    900

accacaccaa tgtcactgcg ccccaagcct ccatgatgtt ccagtacttt gtgaaggtgg    960

tgcccactgt gtacatgaag gtggacggag aggtactgag gacaaatcag ttctctgtga   1020

ccagacatga gaaggttgcc aatgggctgt tgggcgacca aggccttccc ggagtcttcg   1080

tcctctatga gctctcgccc atgatggtga agctgacgga gaagcacagg tccttcaccc   1140

acttcctgac aggtgtgtgc gccatcattg ggggcatgtt cacagtggct ggactcatcg   1200

attcgctcat ctaccactca gcacgagcca tccagaagaa aattgatcta gggaagacaa   1260

cgtagtcacc ctcggtgctt cctctgtctc ctctttctcc ctggcctgtg gttgtccccc   1320

agcctctgcc accctccacc tcctcggtca gccccagccc caggttgata aatctattga   1380

ttgattgtga tagtactc                                                 1398


<210>  9604
<211>  398
<212>  PRT
<213>  Homo sapiens

<400>  9604

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Glu Leu Gly Lys Val Glu 
        115                 120                 125


Val Thr Val Phe Asp Pro Asp Ser Leu Asp Pro Asp Arg Cys Glu Ser 
    130                 135                 140


Cys Tyr Gly Ala Glu Ala Glu Asp Ile Lys Cys Cys Asn Thr Cys Glu 
145                 150                 155                 160


Asp Val Arg Glu Ala Tyr Arg Arg Arg Gly Trp Ala Phe Lys Asn Pro 
                165                 170                 175


Asp Thr Ile Glu Gln Cys Arg Arg Glu Gly Phe Ser Gln Lys Met Gln 
            180                 185                 190


Glu Gln Lys Asn Glu Gly Cys Gln Val Tyr Gly Phe Leu Glu Val Asn 
        195                 200                 205


Lys Val Ala Gly Asn Phe His Phe Ala Pro Gly Lys Ser Phe Gln Gln 
    210                 215                 220


Ser His Val His Gly Cys Val Cys Arg Leu Lys Met Ile Ala Arg Ser 
225                 230                 235                 240


Leu Ala Cys Val His Asp Leu Gln Ser Phe Gly Leu Asp Asn Ile Asn 
                245                 250                 255


Met Thr His Tyr Ile Gln His Leu Ser Phe Gly Glu Asp Tyr Pro Gly 
            260                 265                 270


Ile Val Asn Pro Leu Asp His Thr Asn Val Thr Ala Pro Gln Ala Ser 
        275                 280                 285


Met Met Phe Gln Tyr Phe Val Lys Val Val Pro Thr Val Tyr Met Lys 
    290                 295                 300


Val Asp Gly Glu Val Leu Arg Thr Asn Gln Phe Ser Val Thr Arg His 
305                 310                 315                 320


Glu Lys Val Ala Asn Gly Leu Leu Gly Asp Gln Gly Leu Pro Gly Val 
                325                 330                 335


Phe Val Leu Tyr Glu Leu Ser Pro Met Met Val Lys Leu Thr Glu Lys 
            340                 345                 350


His Arg Ser Phe Thr His Phe Leu Thr Gly Val Cys Ala Ile Ile Gly 
        355                 360                 365


Gly Met Phe Thr Val Ala Gly Leu Ile Asp Ser Leu Ile Tyr His Ser 
    370                 375                 380


Ala Arg Ala Ile Gln Lys Lys Ile Asp Leu Gly Lys Thr Thr 
385                 390                 395


<210>  9605
<211>  530
<212>  DNA
<213>  Homo sapiens

<400>  9605
gccggctggc gtcccctttc cggccggtcc ccatggaggc gctggggaag ctgaagcagt     60

tcgatgccta ccccaagact ttggaggact tccgggtcaa gacctgcggg ggcgccaccg    120

tgaccattgt cagtggcctt ctcatgctgc tactgttcct gtccgagctg cagtattacc    180

tcaccacgga gatctgagta ttgatgccat ggatgtggcc ggagaacagc agctggatgt    240

ggaacacaac ctgttcaagc aacgactaga taaagatggc atccccgtga gctcagaggc    300

tgagcggcat gagcttggga aagtcgaggt gacggtgttt gaccctgact ccctggaccc    360

tgatcgctgt gagagctgct atggtgctga ggcagaagat atcaagtgct gtaacacctg    420

tgaagatgtg cgggaggcat atcgccgtag aggctgggcc ttcaagaacc cagatactat    480

tgagcagtgc cggcgagagg gcttcagcca gaagatgcag gagcagaaga               530


<210>  9606
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  9606

Met Asp Val Ala Gly Glu Gln Gln Leu Asp Val Glu His Asn Leu Phe 
1               5                   10                  15


Lys Gln Arg Leu Asp Lys Asp Gly Ile Pro Val Ser Ser Glu Ala Glu 
            20                  25                  30


Arg His Glu Leu Gly Lys Val Glu Val Thr Val Phe Asp Pro Asp Ser 
        35                  40                  45


Leu Asp Pro Asp Arg Cys Glu Ser Cys Tyr Gly Ala Glu Ala Glu Asp 
    50                  55                  60


Ile Lys Cys Cys Asn Thr Cys Glu Asp Val Arg Glu Ala Tyr Arg Arg 
65                  70                  75                  80


Arg Gly Trp Ala Phe Lys Asn Pro Asp Thr Ile Glu Gln Cys Arg Arg 
                85                  90                  95


Glu Gly Phe Ser Gln Lys Met Gln Glu Gln 
            100                 105


<210>  9607
<211>  2843
<212>  DNA
<213>  Homo sapiens

<400>  9607
cccctttccg gccggtcccc atggaggcgc tggggaagct gaagcagttc gatgcctacc     60

ccaagacttt ggaggacttc cgggtcaaga cctgcggggg cgccaccgtg accattgtca    120

gtggccttct catgctgcta ctgttcctgt ccgagctgca gtattacctc accacggagg    180

tgcatcctga gctctacgtg gacaagtcgc ggggagataa actgaagatc aacatcgatg    240

tactttttcc gcacatgcct tgtgcctatc tgagtattga tgccatggat gtggccggag    300

aacagcagct ggatgtggaa cacaacctgt tcaagcaacg actagataaa gatggcatcc    360

ccgtgagctc agaggctgag cggcatggta accaggggag ggggccgggt ctcagatccc    420

aaagctggat gtacccaagc ctatctgcta gcaagtgaac tgtggcaggc atagtgatac    480

attaaacaac taagagctag agaagtcaag tgacttgcct agggtccccc agctagtaag    540

agtcagagtg agctaaaatc ctctatacat atcgagtcag gtaatctacc tggctattat    600

tctcagaggt cctcaatacc tgcagatggt agtttgaata ccagaggttt gaagataggt    660

cttatgtgct cttgccttgg tagaactgtc tagatggacc caggcttctt tgagtgtttg    720

ctttcccagc ccattggctt aattcagccc ttaatgctct tcccctttgg aatgcaggtg    780

gtttaatgag aatttaggtt ctcaagtcag attgcctggg ttcacatcta gctttgtctc    840

ctgcagtctg tgagcttcag ctagaaagtg gtaataaaac agtagtacca accacatgga    900

attgtaagat caaatgaagt catatgtgta aaatgcctgg tacagagtgg gtacccactt    960

ttaccttcct ttcctttatc ttggtggctt cccaattccc ttcgttaact cagtttccca   1020

ccacagcaaa ctgtcctcaa agctgggatt tctaacacct tagagattac tctggtgggg   1080

agttttatca ttcgttgttt cagcagatta atgcaggaca ccagtggaac caacataatt   1140

tgctatagga ctggatgtgg agtggaggag agcaaagtca tggttgttga ttccaacgct   1200

ttcagcctga gcaaatgaat gacttgagat ggagatgact ggaggagaag gtttttttgg   1260

tgggagggag gagtggctat tggatatcca ctgctgtgta acaaagtact ccaaaagtta   1320

gtagtttgat acaataaaaa tgtgtttttt cagtttccct gggtcaggaa tttaggagtg   1380

gcttgtttgg gtgattcggg attagggtat ctcacgaggt tgcagtcatc taaggattga   1440

tggggcactg aagaatctac tatctatcta tctatctatc tatctatcta tctatctatc   1500

tatctgtcta tcttgagaca gagtctcact ttgtcgccca ggctggagtg cagtggcgcg   1560

atcttggctc actgcaacct ccgcctccca ggttcaagtg attctcctgc ctcaacctcc   1620

cgagtagctg ggattacagg cctgtgccac catgcccagc taattttttg tatttttagt   1680

agagacgggg ttgcaccttg ttgggccaga tggtcttgat ctcttgacct tgtgatccac   1740

ccgcctcagc cttccaaagt gctgggatta caggcatgag ccactgcgcc tggcctactt   1800

atttgttgtt taaatttatt ttttttctgt caaggtgttc tttatttcag agagagggca   1860

ggacaggggg ctcagtcttt cttggcatca gctttcctca tgatggctgg gacattgctc   1920

agctcctcct gcctcctctt agtgcggatg tgcgtcccca ctcttttctt gatgaacttg   1980

agggcccgtt tgtccttgga gaccttgagt aacaccatgg cgtgccgctc atacggggcg   2040

aaaccacaca cctctcggat catgtcccac atgaatttgg tgtttggtca ggcgcccgcg   2100

gcggcagctg tgcctgggct tgctcatgtt cttggtcatc ttgtggccct tgtcaaggca   2160

cacggccata gtgggtagca cagagccatg gctgctgctc tccaatggca gctgtggcag   2220

aagggctggt gccacgcggg gatctacttt tttttttttt tttttttttt ttttgagtca   2280

cgctctgtca cccaggctgg agtgcaatgg tgcgatttca gctcactgca acctctgcct   2340

cccggcttca agtgattcac ctgcctcagc cttctgagta gctggggtta caggcgcctg   2400

cccccacacc cggctacttt ttgtattttt ggtagagaca gggtttcacc atcgtggcca   2460

ggctggtctc aaactcctga cctcaggtga tccacccgcc ttggcctccc aaagtgttgg   2520

gattacaggc atgggccacc acgcccagca ggggatctgc ttttaaaggg ctcactcata   2580

gggctgttgg caggatgcct cagtgcctca ccacatgggc ctctcagtag ggttgcttgt   2640

gtgtccttgt atcacggcaa ctggcttccc ccacttggat cttgcaagtg agctgagaga   2700

acaaagtaga aaccataacc tttggccagg catggtggct cacgcctgta gtcccagcac   2760

ttttggaggc tgaggcagtt ggatcacctg aagtcaggag ttcaagacca gcctggccaa   2820

catggtaaaa ccccatctct act                                           2843


<210>  9608
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  9608

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Leu Thr Thr Glu Val His Pro Glu Leu Tyr Val Asp Lys Ser Arg 
    50                  55                  60


Gly Asp Lys Leu Lys Ile Asn Ile Asp Val Leu Phe Pro His Met Pro 
65                  70                  75                  80


Cys Ala Tyr Leu Ser Ile Asp Ala Met Asp Val Ala Gly Glu Gln Gln 
                85                  90                  95


Leu Asp Val Glu His Asn Leu Phe Lys Gln Arg Leu Asp Lys Asp Gly 
            100                 105                 110


Ile Pro Val Ser Ser Glu Ala Glu Arg His Gly Asn Gln Gly Arg Gly 
        115                 120                 125


Pro Gly Leu Arg Ser Gln Ser Trp Met Tyr Pro Ser Leu Ser Ala Ser 
    130                 135                 140


Lys 
145


<210>  9609
<211>  720
<212>  DNA
<213>  Homo sapiens

<400>  9609
tttccggccg gtccccatgg aggcgctggg gaagctgaag cagttcgatg cctaccccaa     60

gactttggag gacttccggg tcaagacctg cgggggcgcc accgtgacca ttgtcagtgg    120

ccttctcatg ctgctactgt tcctgtccga gctgcagtat tacccactac atccagcacc    180

tgtcatttgg ggaggactat ccaggcattg tgaaccccct ggaccacacc aatgtcactg    240

cgccccaagc ctccatgatg ttccagtact ttgtgaaggt ggtgcccact gtgtacatga    300

aggtggacgg agaggtactg aggacaaatc agttctctgt gaccagacat gagaaggttg    360

ccaatgggct gttgggcgac caaggccttc ccggagtctt cgtcctctat gagctctcgc    420

ccatgatggt gaagctgacg gagaagcaca ggtccttcac ccacttcctg acaggtgtgt    480

gcgccatcat tgggggcatg ttcacagtgg ctggactcat cgattcgctc atctaccact    540

cagcacgagc catccagaag aaaattgatc tagggaagac aacgtagtca ccctcggtgc    600

ttcctctgtc tcctctttct ccctggcctg tggttgtccc ccagcctctg ccaccctcca    660

cctcctcggt cagccccagc cccaggttga taaatctatt gattgattgt gatagtactc    720


<210>  9610
<211>  111
<212>  PRT
<213>  Homo sapiens

<400>  9610

Met Glu Ala Leu Gly Lys Leu Lys Gln Phe Asp Ala Tyr Pro Lys Thr 
1               5                   10                  15


Leu Glu Asp Phe Arg Val Lys Thr Cys Gly Gly Ala Thr Val Thr Ile 
            20                  25                  30


Val Ser Gly Leu Leu Met Leu Leu Leu Phe Leu Ser Glu Leu Gln Tyr 
        35                  40                  45


Tyr Pro Leu His Pro Ala Pro Val Ile Trp Gly Gly Leu Ser Arg His 
    50                  55                  60


Cys Glu Pro Pro Gly Pro His Gln Cys His Cys Ala Pro Ser Leu His 
65                  70                  75                  80


Asp Val Pro Val Leu Cys Glu Gly Gly Ala His Cys Val His Glu Gly 
                85                  90                  95


Gly Arg Arg Gly Thr Glu Asp Lys Ser Val Leu Cys Asp Gln Thr 
            100                 105                 110


<210>  9611
<211>  829
<212>  DNA
<213>  Homo sapiens

<400>  9611
ggggaagctg aagcagttcg atgcctaccc caagactttg gaggacttcc gggtcaagac     60

ctgcgggggc gccaccgtga ccattgtcag tggccttctc atagctgcta tggtgctgag    120

gcagaagata tcaagtgctg taacacctgt gaagatgtgc gggaggcata tcgccgtaga    180

ggctgggcct tcaagaaccc agatactatt gagcagtgcc ggcgagaggg cttcagccag    240

aagatgcagg agcagaagaa tgaaggctgc caggtgtatg gcttcttgga agtcaataag    300

gtggccggaa acttccactt tgcccctggg aagagcttcc agcagtccca tgtgcacgtc    360

catgacttgc agagctttgg ccttgacaac atcaacatga cccactacat ccagcacctg    420

tcatttgggg aggactatcc aggcattgtg aaccccctgg accacaccaa tgtcactgcg    480

ccccaagcct ccatgatgtt ccagtacttt gtgaaggtgg tgcccactgt gtacatgaag    540

gtggacggag aggtactgag gacaaatcag ttctctgtga ccagacatga gaaggttgcc    600

aatgggctgt tgggcgacca aggccttccc ggagtcttcc tcatctacca ctcagcacga    660

gccatccaga agaaaattga tctagggaag acaacgtagt caccctcggt gcttcctctg    720

tctcctcttt ctccctggcc tgtggttgtc ccccagcctc tgccaccctc cacctcctcg    780

gtcagcccca gccccaggtt gataaatcta ttgattgatt gtgatagta                829


<210>  9612
<211>  151
<212>  PRT
<213>  Homo sapiens

<400>  9612

Met Gln Glu Gln Lys Asn Glu Gly Cys Gln Val Tyr Gly Phe Leu Glu 
1               5                   10                  15


Val Asn Lys Val Ala Gly Asn Phe His Phe Ala Pro Gly Lys Ser Phe 
            20                  25                  30


Gln Gln Ser His Val His Val His Asp Leu Gln Ser Phe Gly Leu Asp 
        35                  40                  45


Asn Ile Asn Met Thr His Tyr Ile Gln His Leu Ser Phe Gly Glu Asp 
    50                  55                  60


Tyr Pro Gly Ile Val Asn Pro Leu Asp His Thr Asn Val Thr Ala Pro 
65                  70                  75                  80


Gln Ala Ser Met Met Phe Gln Tyr Phe Val Lys Val Val Pro Thr Val 
                85                  90                  95


Tyr Met Lys Val Asp Gly Glu Val Leu Arg Thr Asn Gln Phe Ser Val 
            100                 105                 110


Thr Arg His Glu Lys Val Ala Asn Gly Leu Leu Gly Asp Gln Gly Leu 
        115                 120                 125


Pro Gly Val Phe Leu Ile Tyr His Ser Ala Arg Ala Ile Gln Lys Lys 
    130                 135                 140


Ile Asp Leu Gly Lys Thr Thr 
145                 150


<210>  9613
<211>  1312
<212>  DNA
<213>  Homo sapiens

<400>  9613
tggaattagc tgaaatctgt ttcctcggtt gcattgggca aagtcacttc tcatcagtga     60

gcctcaacat cttctcagta aaacagggat aattaccgcc accctcaaag agtcattgtg    120

gggatgaaat gagatgatgg ttgtgaagta cagtgatctg tacacagcta atgttcagta    180

tttactgttg actgttttct tactgtttct tttattaaaa gaattgatat gtgtgtagaa    240

gtgcttaatg cctgacccgt agcatgtact atatgaatat tagttattat aacttttatt    300

atccctaagc aaagggcttg tgcagactgg agccaccgat ttcactgtgt ctggccccag    360

ctgatgcctc tgcttctccc ctccccttag agcttgggaa agtcgaggtg acggtgtttg    420

accctgactc cctggaccct gatcgctgtg agagctgcta tggtgctgag gcagaagata    480

tcaagtgctg taacacctgt gaagatgtgc gggaggcata tcgccgtaga ggctgggcct    540

tcaagaaccc agatactatt gagcagtgcc ggcgagaggg cttcagccag aagatgcagg    600

agcagaagaa tgaaggctgc caggtgtatg gcttcttgga agtcaataag gtggccggaa    660

acttccactt tgcccctggg aagagcttcc agcagtccca tgtgcacggt gagtgatctg    720

cactagctgg ggagatttag atgctggcca ccttcttggt gagcttgagt ggtcctcttc    780

tgcctgctgc tcatttgtct tgggcaacca tttggccaga gcaggccttc atctcagggc    840

agcagtttgg cacagtggct aagagcacag gccgaggagc cagactgcct gcattcagat    900

accagtttca gaccttactg gctgtgtgac tttgagaagg tttcttaatc tttttgactc    960

ctgttttcta ctttataaaa tgttgatgag ggcacttatc tcacagggtg tgtgtgcagg   1020

ttaaagatga tagcacggag cctggcttgt ggtaggtact tgttgaaatg gtagcccccc   1080

gtgtccgatg atgacctgtg catgaggctt tgggagaagc agagctaggt tggagcacag   1140

gttctgccac acctgggcta tgtcatattt gggccctatt tagttgcttc ttctgtaaaa   1200

tggggatgat gataatagta cccactcaca gggctgttgg ggtgaacaaa tgagatttat   1260

tctcattcat ttgttcattc atgcattcac aaaatattta gtaatcacct ac           1312


<210>  9614
<211>  88
<212>  PRT
<213>  Homo sapiens

<400>  9614

Met Val Leu Arg Gln Lys Ile Ser Ser Ala Val Thr Pro Val Lys Met 
1               5                   10                  15


Cys Gly Arg His Ile Ala Val Glu Ala Gly Pro Ser Arg Thr Gln Ile 
            20                  25                  30


Leu Leu Ser Ser Ala Gly Glu Arg Ala Ser Ala Arg Arg Cys Arg Ser 
        35                  40                  45


Arg Arg Met Lys Ala Ala Arg Cys Met Ala Ser Trp Lys Ser Ile Arg 
    50                  55                  60


Trp Pro Glu Thr Ser Thr Leu Pro Leu Gly Arg Ala Ser Ser Ser Pro 
65                  70                  75                  80


Met Cys Thr Val Ser Asp Leu His 
                85


<210>  9615
<211>  971
<212>  DNA
<213>  Homo sapiens

<400>  9615
cagggtctgt tctaaagact cctgaggagg gcgtgaactc tcacacaggc ccaaggcttg     60

ccctttctgg ctgtccttaa gcaggaccag gaggtgccag gctggagaag gaatgagggg    120

cagagaagac aggtggtttg cagtccaggg ggaggaagga ggaggccagt gctgctccta    180

ctaatgacgc cttctccctt gccttctccc ttctctccta gtccatgact tgcagagctt    240

tggccttgac aaccctccat gatgttccag tactttgtga aggtggtgcc cactgtgtac    300

atgaaggtgg acggagaggt gagtcaggga gctccctacc agagtctcct gcgcggtgcc    360

aagcactgga gttcctgcat tttgttccgt cagcctgggg agtgaaagct gcctcgtcct    420

cacatggcga ataaaagact gaggcacaga gagggtgggg gatttgccct cccaggcaga    480

gtgcaggcct ggggctgtta gatttaaagc gcctgctctt tctgctgccc tcaccgcttc    540

tatccgttcc tccggtgccc accgtctgcc tgcctcactg ttctctgtgg tctgcctggg    600

ctgggggtta ggcaaggcaa gtctctgtgt acccgctccc aaggctgccc tggcctgtgg    660

agcagcatct cagcagagtg gcaggatgcg aggggctgag ggcagaggaa gtcaggtcag    720

ccttggtgcg tctttggaga gctgcttctc agcctggacc cccgtgagaa cacccaccaa    780

atgctgccag gataggtaaa ctgtaaagac ttggcacctg gaggggaagg ctgaggccaa    840

gactaggaga gggggtctgg cgggccaggc cttgcagtgc aggccactag cacggtgctg    900

tgttctctcc ttacacggcc aaggctcaac aggaaagggg aaggagcagg ggtggggctg    960

atggtggctg g                                                         971


<210>  9616
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  9616

Met Thr Cys Arg Ala Leu Ala Leu Thr Thr Leu His Asp Val Pro Val 
1               5                   10                  15


Leu Cys Glu Gly Gly Ala His Cys Val His Glu Gly Gly Arg Arg Gly 
            20                  25                  30


Glu Ser Gly Ser Ser Leu Pro Glu Ser Pro Ala Arg Cys Gln Ala Leu 
        35                  40                  45


Glu Phe Leu His Phe Val Pro Ser Ala Trp Gly Val Lys Ala Ala Ser 
    50                  55                  60


Ser Ser His Gly Glu 
65


<210>  9617
<211>  606
<212>  DNA
<213>  Homo sapiens

<400>  9617
cagagctttg gatgagctct ggatggtgtt gtttacagat caacatgacc cactacatcc     60

agcacctgtc atttggggag gactatccag gcattgtgaa ccccctggac cacaccaatg    120

tcactgcgcc ccaagcctcc atgatgttcc agtactttgt gaaggtggtg cccactgtgt    180

acatgaaggt ggacggagag gtactgagga caaatcagtt ctctgtgacc agacatgaga    240

aggttgccaa tgggctgttg ggcgaccaag gccttcccgg agtcttcgtc ctctatgagc    300

tctcgcccat gatggtgaag ctgacggaga agcacaggtc cttcacccac ttcctgacag    360

gtgtgtgcgc catcattggg ggcatgttca cagtggctgg actcatcgat tcgctcatct    420

accactcagc acgagccatc cagaagaaaa ttgatctagg gaagacaacg tagtcaccct    480

cggtgcttcc tctgtctcct ctttctccct ggcctgtggt tgtcccccag cctctgccac    540

cctccacctc ctcggtcagc cccagcccca ggttgataaa tctattgatt gattgtgata    600

gtactc                                                               606


<210>  9618
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  9618

Met Ser Ser Gly Trp Cys Cys Leu Gln Ile Asn Met Thr His Tyr Ile 
1               5                   10                  15


Gln His Leu Ser Phe Gly Glu Asp Tyr Pro Gly Ile Val Asn Pro Leu 
            20                  25                  30


Asp His Thr Asn Val Thr Ala Pro Gln Ala Ser Met Met Phe Gln Tyr 
        35                  40                  45


Phe Val Lys Val Val Pro Thr Val Tyr Met Lys Val Asp Gly Glu Val 
    50                  55                  60


Leu Arg Thr Asn Gln Phe Ser Val Thr Arg His Glu Lys Val Ala Asn 
65                  70                  75                  80


Gly Leu Leu Gly Asp Gln Gly Leu Pro Gly Val Phe Val Leu Tyr Glu 
                85                  90                  95


Leu Ser Pro Met Met Val Lys Leu Thr Glu Lys His Arg Ser Phe Thr 
            100                 105                 110


His Phe Leu Thr Gly Val Cys Ala Ile Ile Gly Gly Met Phe Thr Val 
        115                 120                 125


Ala Gly Leu Ile Asp Ser Leu Ile Tyr His Ser Ala Arg Ala Ile Gln 
    130                 135                 140


Lys Lys Ile Asp Leu Gly Lys Thr Thr 
145                 150


<210>  9619
<211>  548
<212>  DNA
<213>  Homo sapiens

<400>  9619
gctgcctcgt cctcacatgg cgaataaaag actgaggcac agagagggtg ggggatttgc     60

cctcccaggc agagtgcagg cctggggctg ttagatttaa agcgcctgct ctttctgctg    120

ccctcaccgc ttctatccgt tcctccggtg cccaccgtct gcctgcctca ctgttctctg    180

tggtctgcct gggctggggg ttaggcaagg caagtctctg tgtacccgct cccaaggctg    240

ccctggcctg tggagcagca tctcagcaga gtggcaggat gcgaggggct gagggcagag    300

gaagtcaggt cagccttggt gcgtctttgg agagctgctt ctcagcctgg acccccgtga    360

gaacacccac caaatgctgc caggataggt actgaggaca aatcagttct ctgtgaccag    420

acatgagaag gttgccaatg ggctgttggg cgaccaaggc cttcccggag tcttcgtcct    480

tctgtctcct ctttctccct ggcctgtggt tgtcccccag cctctgccac cctccacctc    540

ctcggtca                                                             548


<210>  9620
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9620

Met Arg Arg Leu Pro Met Gly Cys Trp Ala Thr Lys Ala Phe Pro Glu 
1               5                   10                  15


Ser Ser Ser Phe Cys Leu Leu Phe Leu Pro Gly Leu Trp Leu Ser Pro 
            20                  25                  30


Ser Leu Cys His Pro Pro Pro Pro Arg 
        35                  40


<210>  9621
<211>  1018
<212>  DNA
<213>  Homo sapiens

<400>  9621
gctgcctcgt cctcacatgg cgaataaaag actgaggcac agagagggtg ggggatttgc     60

cctcccaggc agagtgcagg cctggggctg ttagatttaa agcgcctgct ctttctgctg    120

ccctcaccgc ttctatccgt tcctccggtg cccaccgtct gcctgcctca ctgttctctg    180

tggtctgcct gggctggggg ttaggcaagg caagtctctg tgtacccgct cccaaggctg    240

ccctggcctg tggagcagca tctcagcaga gtggcaggat gcgaggggct gagggcagag    300

gaagtcaggt cagccttggt gcgtctttgg agagctgctt ctcagcctgg acccccgtga    360

gaacacccac caaatgctgc caggataggt aaactgtaaa gacttggcac ctggagggga    420

aggctgaggc caagactagg agagggggtc tggcgggcca ggccttgcag tgcaggccac    480

tagcacggtg ctgtgttctc tccttacacg gccaaggctc aacaggaaag gggaaggagc    540

aggggtgggg ctgatggtgg ctggagccag gtcctagccc tagccctggc ccaggctccc    600

ctcccacccc aggtactgag gacaaatcag ttctctgtga ccagacatga gaaggttgcc    660

aatgggctgt tgggcgacca aggccttccc ggagtcttcg tcctctatga gctctcgccc    720

atgatggtga agctgacgga gaagcacagg tccttcaccc acttcctgac aggtgtgtgc    780

gccatcattg ggggcatgtt cacagtggct ggactcatcg attcgctcat ctaccactca    840

gcacgagcca tccagaagaa aattgatcta gggaagacaa cgtagtcacc ctcggtgctt    900

cctctgtctc ctctttctcc ctggcctgtg gttgtccccc agcctctgcc accctccacc    960

tcctcggtca gccccagccc caggttgata aatctattga ttgattgtga tagtactc     1018


<210>  9622
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  9622

Met Met Val Lys Leu Thr Glu Lys His Arg Ser Phe Thr His Phe Leu 
1               5                   10                  15


Thr Gly Val Cys Ala Ile Ile Gly Gly Met Phe Thr Val Ala Gly Leu 
            20                  25                  30


Ile Asp Ser Leu Ile Tyr His Ser Ala Arg Ala Ile Gln Lys Lys Ile 
        35                  40                  45


Asp Leu Gly Lys Thr Thr 
    50


<210>  9623
<211>  794
<212>  DNA
<213>  Homo sapiens

<400>  9623
gctgcctcgt cctcacatgg cgaataaaag actgaggcac agagagggtg ggggatttgc     60

cctcccaggc agagtgcagg cctggggctg ttagatttaa agcgcctgct ctttctgctg    120

ccctcaccgc ttctatccgt tcctccggtg cccaccgtct gcctgcctca ctgttctctg    180

tggtctgcct gggctggggg ttaggcaagg caagtctctg tgtacccgct cccaaggctg    240

ccctggcctg tggagcagca tctcagcaga gtggcaggat gcgaggggct gagggcagag    300

gaagtcaggt cagccttggt gcgtctttgg agagctgctt ctcagcctgg acccccgtga    360

gaacacccac caaatgctgc caggataggt actgaggaca aatcagttct ctgtgaccag    420

acatgagaag gttgccaatg ggctgttggg cgaccaaggc cttcccggag tcttcgtcct    480

ctatgagctc tcgcccatga tggtgaagct gacggagaag cacaggtcct tcacccactt    540

cctgacaggt gtgtgcgcca tcattggggg catgttcaca gtggctggac tcatcgattc    600

gctcatctac cactcagcac gagccatcca gaagaaaatt gatctaggga agacaacgta    660

gtcaccctcg gtgcttcctc tgtctcctct ttctccctgg cctgtggttg tcccccagcc    720

tctgccaccc tccacctcct cggtcagccc cagccccagg ttgataaatc tattgattga    780

ttgtgatagt actc                                                      794


<210>  9624
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  9624

Met Met Val Lys Leu Thr Glu Lys His Arg Ser Phe Thr His Phe Leu 
1               5                   10                  15


Thr Gly Val Cys Ala Ile Ile Gly Gly Met Phe Thr Val Ala Gly Leu 
            20                  25                  30


Ile Asp Ser Leu Ile Tyr His Ser Ala Arg Ala Ile Gln Lys Lys Ile 
        35                  40                  45


Asp Leu Gly Lys Thr Thr 
    50


<210>  9625
<211>  282
<212>  DNA
<213>  Homo sapiens

<400>  9625
ggctgttggg cgaccaaggc cttcccggag tcttcgtcct ctatgagctc atcattgggg     60

gcatgttcac agtggctgga ctcatcgatt cgctcatcta ccactcagca cgagccatcc    120

agaagaaaat tgatctaggg aagacaacgt agtcaccctc ggtgcttcct ctgtctcctc    180

tttctccctg gcctgtggtt gtcccccagc ctctgccacc ctccacctcc tcggtcagcc    240

ccagccccag gttgataaat ctattgattg attgtgatag ta                       282


<210>  9626
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9626

Met Ser Ser Ser Leu Gly Ala Cys Ser Gln Trp Leu Asp Ser Ser Ile 
1               5                   10                  15


Arg Ser Ser Thr Thr Gln His Glu Pro Ser Arg Arg Lys Leu Ile 
            20                  25                  30


<210>  9627
<211>  2226
<212>  DNA
<213>  Homo sapiens

<400>  9627
aaccgattct atagccacca cagagcaaac tgtgggctgg cctcccagta tgaagtgtgg     60

gtccagcagg gcccacagga gccattctga gtttctggcc aaacacattc aagctcacat    120

tcccttttgt gtctccagat cctatgattt catggaaggg gaccctccca cccaccgcca    180

ctgccaacca agacatagct cagtggtcaa gacttgggct tgggagtcgg gatcctgtaa    240

cgaatgtcac ttgaccgctt tcttttttta tgaaacagtc tcgctctgtc tcccaggttg    300

gagtgcagtg gcacgatctc ggctgactgc aacctccacc tcctgggttc aagcgattct    360

cctgcctcag cctccccagt agctgggatt acaggcgtgg gcccccatgt ccagctaatt    420

tttatatttt cgctctgtct cccaggttgg agtgcagtgg cacgatctcg gctgactgca    480

acctccacct cctgggttca agcgattctc ctgcctcagc ctccccagta gctgggatta    540

caggcgtggg cccccatgtc cagctaattt ttatattttt agtagagaca gggtttcacc    600

atgttgtcca ggctggtctt gaacccctga cctcaagtga tccacccacc tctgcctccc    660

aaagtgctgg gattacaggt gtgagccacc atgccaggcc ctcttaacct cttcaagtct    720

gttttctcat ctgcaaaaca gaggtaataa gatcagtatc ttcttaatgg aagcacctgg    780

actacatttt tttcattcat tgttatcata aatgaggact aacctgtctc ccgttgggag    840

ttttgaacct agacctcatg tcttcatgac gtcatcactg ccccaggccc agctgtgtcc    900

ctacaccagc cccagctgac gcatcttctt tttctgcctg tagagatggt tacaatgcct    960

ggcgtgatgc attctggcct tcgcagatcc tggcggggct gtgccaacgc tgtggcctcc   1020

ctgcccctga ataccgagcc ggtgctgtca aggtgggcag caaagtcttc ctgacaccac   1080

cggagaccct gcccccaggg atctcttcac atgtggattg acatctttcc tcaagatgtg   1140

cctgctccac ccccagttga catcaagcct cggcagccaa tcagctatga gctcagagtt   1200

gtcatctgga acacggagga tgtggttctg gatgacgaga atccactcac cggagagatg   1260

tcgagtgaca tctatgtgaa gagctgggtg aaggggttgg agcatgacaa gcaggagaca   1320

gacgttcact tcaactccct gactggggag gggaacttca attggcgctt tgtgttccgc   1380

tttgactacc tgcccacgga gcgggaggtg agcgtctggc gcaggtctgg accctttgcc   1440

ctggaggagg cggagttccg gcagcctgca gtgctggtcc tgcaggtctg ggactatgac   1500

cgcatctctg ccaatgactt ccttggatcc ctggagttgc agctaccaga catggtgcgt   1560

ggggcccggg gccccgagct ctgctctgtg cagctggccc gcaatggggc cgggccgagg   1620

tgcaatctgt ttcgctgccg ccgcctgagg ggctggtggc cggtagtgaa gctgaaggag   1680

gcagaggacg tggagcggga ggcgcaggag gctcaggctg gcaagaagaa gcgaaagcag   1740

aggaggagga agggccggcc agaagacctg gagttcacag acatgggtgg caatgtgtac   1800

atcctcacgg gcaaggtgga ggcagagttt gagctgctga ctgtggagga ggccgagaaa   1860

cggccagtgg ggaaggggcg gaagcagcca gagcctctgg agaaacccag ccgccccaaa   1920

acttccttca actggtttgt gaacccgctg aagacctttg tcttcttcat ctggcgccgg   1980

tactggcgca ccctggtgct gctgctactg gtgctgctca ccgtcttcct cctcctggtc   2040

ttctacacca tccctggcca gatcagccag gtcatcttcc gtcccctcca caagtgactc   2100

tcgctgacct tggacactca cccagggtgc caacccttca atgcctgctc ctggaagtct   2160

ttcttaccca tgtgagctac cccagagtct agtgcttcct ctgaataaac ctatcacagc   2220

cactga                                                              2226


<210>  9628
<211>  328
<212>  PRT
<213>  Homo sapiens

<400>  9628

Met Trp Ile Asp Ile Phe Pro Gln Asp Val Pro Ala Pro Pro Pro Val 
1               5                   10                  15


Asp Ile Lys Pro Arg Gln Pro Ile Ser Tyr Glu Leu Arg Val Val Ile 
            20                  25                  30


Trp Asn Thr Glu Asp Val Val Leu Asp Asp Glu Asn Pro Leu Thr Gly 
        35                  40                  45


Glu Met Ser Ser Asp Ile Tyr Val Lys Ser Trp Val Lys Gly Leu Glu 
    50                  55                  60


His Asp Lys Gln Glu Thr Asp Val His Phe Asn Ser Leu Thr Gly Glu 
65                  70                  75                  80


Gly Asn Phe Asn Trp Arg Phe Val Phe Arg Phe Asp Tyr Leu Pro Thr 
                85                  90                  95


Glu Arg Glu Val Ser Val Trp Arg Arg Ser Gly Pro Phe Ala Leu Glu 
            100                 105                 110


Glu Ala Glu Phe Arg Gln Pro Ala Val Leu Val Leu Gln Val Trp Asp 
        115                 120                 125


Tyr Asp Arg Ile Ser Ala Asn Asp Phe Leu Gly Ser Leu Glu Leu Gln 
    130                 135                 140


Leu Pro Asp Met Val Arg Gly Ala Arg Gly Pro Glu Leu Cys Ser Val 
145                 150                 155                 160


Gln Leu Ala Arg Asn Gly Ala Gly Pro Arg Cys Asn Leu Phe Arg Cys 
                165                 170                 175


Arg Arg Leu Arg Gly Trp Trp Pro Val Val Lys Leu Lys Glu Ala Glu 
            180                 185                 190


Asp Val Glu Arg Glu Ala Gln Glu Ala Gln Ala Gly Lys Lys Lys Arg 
        195                 200                 205


Lys Gln Arg Arg Arg Lys Gly Arg Pro Glu Asp Leu Glu Phe Thr Asp 
    210                 215                 220


Met Gly Gly Asn Val Tyr Ile Leu Thr Gly Lys Val Glu Ala Glu Phe 
225                 230                 235                 240


Glu Leu Leu Thr Val Glu Glu Ala Glu Lys Arg Pro Val Gly Lys Gly 
                245                 250                 255


Arg Lys Gln Pro Glu Pro Leu Glu Lys Pro Ser Arg Pro Lys Thr Ser 
            260                 265                 270


Phe Asn Trp Phe Val Asn Pro Leu Lys Thr Phe Val Phe Phe Ile Trp 
        275                 280                 285


Arg Arg Tyr Trp Arg Thr Leu Val Leu Leu Leu Leu Val Leu Leu Thr 
    290                 295                 300


Val Phe Leu Leu Leu Val Phe Tyr Thr Ile Pro Gly Gln Ile Ser Gln 
305                 310                 315                 320


Val Ile Phe Arg Pro Leu His Lys 
                325


<210>  9629
<211>  3600
<212>  DNA
<213>  Homo sapiens

<400>  9629
ggaccctggg cagccggaga gctcattgcc gcctttcaac tcattgaact agactacagt     60

ggccgacttg aggtcagcat gccctggcgt ggctagcaca ggctgtgagc ccaacttgtt    120

agtccatcag gccatccagc cctagggaat ataaaacatg gatatgtccc aggaccagcc    180

tccaggtctc ttttccccag agaataaaga ctgcaggttt gtcctgaggt cacctcattg    240

gaccacttga ccccaaggaa cattgcaagt attcatgtgc taggttcacc ttgttgggcc    300

atcctgcatg cctcagacac cctgctccct tcctgcacga agctgcttcc cgagaccccc    360

tcccttccac caatccagcc ttggttggtt cctgtgcatt tacatttcac cagtacctct    420

ccatatcccc tccccacacc taggcttttc ctcctttggc ctgattcctc ttcgccctct    480

gactgtttcc ctcctacagc cctcagtgcc cagtgaggtg gagccccagg atctggcacc    540

cctggttgag ccccactctg gacgcctgtc ccttccaccc aacgtgtgcc cagtgctcag    600

ggagttccgt gttgaggtgc tgttctgggg tcttagggga cttggtcgtg tgcatctgct    660

cgaggtggag cagccccagg ttgtactgga ggtggctggg caaggtgtgg agtctgaggt    720

cctggccagc taccgtgaga gccccaattt cactgagctt gtcaggcatc tgacagtgga    780

cttgccggag cagccttact tgcagcctcc actcagcatc ttggtgattg agcgccgggc    840

ctttggccac acagtccttg tgggttccca cattgtcccc cacatgctgc gattcacatt    900

tcggggtcat gaggatcctc ctgaggagga aggagagatg gaggagacag gggatatgat    960

gcccaaggga cctcaaggac agaagtccct ggatcccttc ttggctgaag cgggtatatc   1020

cagacagctc ctgaagcctc ctctgaagaa gctcccacta ggaggcctcc taaatcaagg   1080

ccctgggctg gaggaagaca tcccagatcc agaggagctc gactgggggt ccaagtacta   1140

tgcgtcgctg caggagctcc aggggcagca caactttgat gaagatgaaa tggatgatcc   1200

tggagattca gatggggtca acctcatttc tatggttggg gagatccaag accaggatct   1260

acaacaggtc cctgaaggaa gaatttaacc actttgaaga ctggctgaat gtgtttcctc   1320

tgtaccgagg gcaagggggc caggatggag gtggagaaga ggaaggatct ggacaccttg   1380

tgggcaagtt caagggctcc ttcctcattt accctgaatc agaggcagtg ttgttctctg   1440

agccccagat ctcccggggg atcccacaga accggcccat caagctcctg gtcagagtgt   1500

atgttgtaaa ggctaccaac ctggctcctg cagaccccaa tggcaaagca gacccttacg   1560

tggtggtgag cgctggccgg gagcggcagg acaccaagga acgctacatc cccaagcagc   1620

tcaaccccat ctttggagag atcctggagc taagcatctc tctcccagct gagacggagc   1680

tgacggtcgc cgtatttgat catgacctcg tgggttctga cgacctcatc ggggagaccc   1740

acattgatct ggaaaaccga ttctatagcc accacagagc aaactgtggg ctggcctccc   1800

agtatgaagt gtgggtccag cagggcccac aggagccatt ctgagtttct ggccaaacac   1860

attcaagctc acattccctt ttgtgtctcc agatcctatg atttcatgga aggggaccct   1920

cccacccacc gccactgcca accaagacat agctcagtgg tcaagactta agcacctgga   1980

ctacattttt ttcattcatt gttatcataa atgaggacta acctgtctcc cgttgggagt   2040

tttgaaccta gacctcatgt cttcatgacg tcatcactgc cccaggccca gctgtgtccc   2100

tacaccagcc ccagctgacg catcttcttt ttctgcctgt agagatggtt acaatgcctg   2160

gcgtgatgca ttctggcctt cgcagatcct ggcggggctg tgccaacgct gtggcctccc   2220

tgcccctgaa taccgagccg gtgctgtcaa ggtgggcagc aaagtcttcc tgacaccacc   2280

ggagaccctg cccccaggga tctcttcaca tgtggattga catctttcct caagatgtgc   2340

ctgctccacc cccagttgac atcaagcctc ggcagccaat cagctatgag ctcagagttg   2400

tcatctggaa cacggaggat gtggttctgg atgacgagaa tccactcacc ggagagatgt   2460

cgagtgacat ctatgtgaag aggtaggctg ctggccgggc ggggcaacgg cggtgcacta   2520

gggggattgc aaatgggtgt gggccctcgg gctgagtcca gagccccgac cccaggccct   2580

ccgtggtgct gagagcgggg tgaggagtgg gttctccatg tagctccagc cctgacgctc   2640

acccaccccg gccccagctg ggtgaagggg ttggagcatg acaagcagga gacagacgtt   2700

cacttcaact ccctgactgg ggaggggaac ttcaattggc gctttgtgtt ccgctttgac   2760

tacctgccca cggagcggga ggtgagcgtc tggcgcaggt ctggaccctt tgccctggag   2820

gaggcggagt tccggcagcc tgcagtgctg gtcctgcagg tctgggacta tgaccgcatc   2880

tctgccaatg acttccttgg atccctggag ttgcagctac cagacatggt gcgtggggcc   2940

cggggccccg agctctgctc tgtgcagctg gcccgcaatg gggccgggcc gaggtgcaat   3000

ctgtttcgct gccgccgcct gaggggctgg tggccggtag tgaagctgaa ggaggcagag   3060

gacgtggagc gggaggcgca ggaggctcag gctggcaaga agaagcgaaa gcagaggagg   3120

aggaagggcc ggccagaaga cctggagttc acagacatgg gtggcaatgt gtacatcctc   3180

acgggcaagg tggaggcaga gtttgagctg ctgactgtgg aggaggccga gaaacggcca   3240

gtggggaagg ggcggaagca gccagagcct ctggagaaac ccagccgccc caaaacttcc   3300

ttcaactggt ttgtgaaccc gctgaagacc tttgtcttct tcatctggcg ccggtactgg   3360

cgcaccctgg tgctgctgct actggtgctg ctcaccgtct tcctcctcct ggtcttctac   3420

accatccctg gccagatcag ccaggtcatc ttccgtcccc tccacaagtg actctcgctg   3480

accttggaca ctcacccagg gtgccaaccc ttcaatgcct gctcctggaa gtctttctta   3540

cccatgtgag ctaccccaga gtctagtgct tcctctgaat aaacctatca cagccactga   3600


<210>  9630
<211>  326
<212>  PRT
<213>  Homo sapiens

<400>  9630

Met Pro Gln Thr Pro Cys Ser Leu Pro Ala Arg Ser Cys Phe Pro Arg 
1               5                   10                  15


Pro Pro Pro Phe His Gln Ser Ser Leu Gly Trp Phe Leu Cys Ile Tyr 
            20                  25                  30


Ile Ser Pro Val Pro Leu His Ile Pro Ser Pro His Leu Gly Phe Ser 
        35                  40                  45


Ser Phe Gly Leu Ile Pro Leu Arg Pro Leu Thr Val Ser Leu Leu Gln 
    50                  55                  60


Pro Ser Val Pro Ser Glu Val Glu Pro Gln Asp Leu Ala Pro Leu Val 
65                  70                  75                  80


Glu Pro His Ser Gly Arg Leu Ser Leu Pro Pro Asn Val Cys Pro Val 
                85                  90                  95


Leu Arg Glu Phe Arg Val Glu Val Leu Phe Trp Gly Leu Arg Gly Leu 
            100                 105                 110


Gly Arg Val His Leu Leu Glu Val Glu Gln Pro Gln Val Val Leu Glu 
        115                 120                 125


Val Ala Gly Gln Gly Val Glu Ser Glu Val Leu Ala Ser Tyr Arg Glu 
    130                 135                 140


Ser Pro Asn Phe Thr Glu Leu Val Arg His Leu Thr Val Asp Leu Pro 
145                 150                 155                 160


Glu Gln Pro Tyr Leu Gln Pro Pro Leu Ser Ile Leu Val Ile Glu Arg 
                165                 170                 175


Arg Ala Phe Gly His Thr Val Leu Val Gly Ser His Ile Val Pro His 
            180                 185                 190


Met Leu Arg Phe Thr Phe Arg Gly His Glu Asp Pro Pro Glu Glu Glu 
        195                 200                 205


Gly Glu Met Glu Glu Thr Gly Asp Met Met Pro Lys Gly Pro Gln Gly 
    210                 215                 220


Gln Lys Ser Leu Asp Pro Phe Leu Ala Glu Ala Gly Ile Ser Arg Gln 
225                 230                 235                 240


Leu Leu Lys Pro Pro Leu Lys Lys Leu Pro Leu Gly Gly Leu Leu Asn 
                245                 250                 255


Gln Gly Pro Gly Leu Glu Glu Asp Ile Pro Asp Pro Glu Glu Leu Asp 
            260                 265                 270


Trp Gly Ser Lys Tyr Tyr Ala Ser Leu Gln Glu Leu Gln Gly Gln His 
        275                 280                 285


Asn Phe Asp Glu Asp Glu Met Asp Asp Pro Gly Asp Ser Asp Gly Val 
    290                 295                 300


Asn Leu Ile Ser Met Val Gly Glu Ile Gln Asp Gln Asp Leu Gln Gln 
305                 310                 315                 320


Val Pro Glu Gly Arg Ile 
                325


<210>  9631
<211>  4935
<212>  DNA
<213>  Homo sapiens

<400>  9631
ccgcccccag ggctcaggct gcgtcccccg aggccgggct cccgcgattt ccagctcctt     60

ggggcgctga gctgttttgg aggcgcccca ggtcgtgttc cacagcggcg cgtccgcagc    120

tgctggccaa cttcttccgt ttcagagcgg cttagccccc ctcccctgcc ctcacccccg    180

aatacttgga ggagatcagg gtgaggtgca gagatttacc agcactcgcc ctccccacgc    240

tcccctccaa cacgcttctc ttgttcccca cagcggggtt taaccctacc ttcggcccgg    300

cctgggtgcc cctctatggc tcgccccccg gcgcggggct ccgggatagt cttcaaggtc    360

tcaacgaagg cgttggccaa ggcatttggt tccgcggccg ccttctgctg gctgtgtcca    420

tgcaggtgtt ggaagggaga gctgaacctg agcctcccca ggcccagcag gggtccacgt    480

tgtcccggct cacccgaaag aagaaaaaga aagccagaag ggatcagacc ccaaaggcgg    540

ttccgcagca cttggacgcc agccccggtg ccgaggggcc tgagatcccc cgtgccatgg    600

aggtggaggt ggaggagctg ctgccgctgc cagagaatgt cctggcgccc tgtgaagatt    660

tcctgctttt cggtgtgctc ttcgaggcca ccatgatcga ccccaccgtg gcctcccagc    720

ccatcagctt cgagatctcc attggtcgcg caggccgtct ggaggagcaa ttgggccgag    780

ggtccagggc tggggaggga actgagggtg cagccgtgga ggctcagcct ctgctgggag    840

ccaggccaga ggaggagaaa gaggaggaag aactggggac ccatgctcag cggcctgagc    900

ccatggacgg cagtgggcca tacttctgct tgcccctctg tcactgcaag ccatgcatgc    960

atgtgtggag ttgctgggag gaccacacct ggcgcctgca gagcagcaac tgcgtgcgca   1020

aagtggccga gaggctggac caggggctgc aggaggttga gagactgcag cgcaagccgg   1080

ggcctggcgc ctgtgcacag ctcaagcagg cactggaagt actggtggct gggagcagac   1140

agttttgcca cggtgccgag cgcaggacga tgacccggcc caatgccctg gatcgatgcc   1200

gagggaaact cctggtgcac agcctgaacc ttttggctaa gcaaggactg cgacttctac   1260

gcggcctgag acggcgcaat gtgcaaaaga aggtggcact ggccaagaag ctcctggcaa   1320

aactgcgctt tctggctgag gagcacaact ttgatgaaga tgaaatggat gatcctggag   1380

attcagatgg ggtcaacctc atttctatgg ttggggagat ccaagaccag ggtgaggctg   1440

aagtcaaagg cactgtgtcc ccaaaaaaag cagttgccac cctgaagatc tacaacaggt   1500

ccctgaagga agaatttaac cactttgaag actggctgaa tgtgtttcct ctgtaccgag   1560

ggcaaggggg ccaggatgga ggtggagaag aggaaggatc tggacacctt gtgggcaagt   1620

tcaagggctc cttcctcatt taccctgaat cagaggcagt gttgttctct gagccccaga   1680

tctcccgggg gatcccacag aaccggccca tcaagctcct ggtcagagtg tatgttgtaa   1740

agctaagaaa cctttgcaaa atccaaggtc atgaagactt ttgcctgttt tctgctgcta   1800

ccaacctggc tcctgcagac cccaatggca aagcagaccc ttacgtggtg gtgagcgctg   1860

gccgggagcg gcaggacacc aaggaacgct acatccccaa gcagctcaac cccatctttg   1920

gagagatcct ggagctaagc atctctctcc cagctgagac ggagctgacg gtcgccgtat   1980

ttgatcatga cctcgtgggt tctgacgacc tcatcgggga gacccacatt gatctggaaa   2040

accgattcta tagccaccac agagcaaact gtgggctggc ctcccagtat gaagtgtggg   2100

tccagcaggg cccacaggag ccattctgag tttctggcca aacacattca agctcacatt   2160

cccttttgtg tctccagatc ctatgatttc atggaagggg accctcccac ccaccgccac   2220

tgccaaccaa gacatagctc agtggtcaag acttgggctt gggagtcggg atcctgtaac   2280

gaatgtcact tgaccgcttt ctttttttat gaaacagtct cgctctgtct cccaggttgg   2340

agtgcagtgg cacgatctcg gctgactgca acctccacct cctgggttca agcgattctc   2400

ctgcctcagc ctccccagta gctgggatta caggcgtggg cccccatgtc cagctaattt   2460

ttatattttc gctctgtctc ccaggttgga gtgcagtggc acgatctcgg ctgactgcaa   2520

cctccacctc ctgggttcaa gcgattctcc tgcctcagcc tccccagtag ctgggattac   2580

aggcgtgggc ccccatgtcc agctaatttt tatattttta gtagagacag ggtttcacca   2640

tgttgtccag gctggtcttg aacccctgac ctcaagtgat ccacccacct ctgcctccca   2700

aagtgctggg attacaggtg tgagccacca tgccaggccc tcttaacctc ttcaagtctg   2760

ttttctcatc tgcaaaacag aggtaataag atcagtatct tcttaatgga agcacctgga   2820

ctacattttt ttcattcatt gttatcataa atgaggacta acctgtctcc cgttgggagt   2880

tttgaaccta gacctcatgt cttcatgacg tcatcactgc cccaggccca gctgtgtccc   2940

tacaccagcc ccagctgacg catcttcttt ttctgcctgt agagatggtt acaatgcctg   3000

gcgtgatgca ttctggcctt cgcagatcct ggcggggctg tgccaacgct gtggcctccc   3060

tgcccctgaa taccgagccg gtgctgtcaa ggtgggcagc aaagtcttcc tgacaccacc   3120

ggagaccctg cccccaggga tctcttcaca tgtggattga catctttcct caagatgtgc   3180

ctgctccacc cccagttgac atcaagcctc ggcagccaat cagctatgag ctcagagttg   3240

tcatctggaa cacggaggat gtggttctgg atgacgagaa tccactcacc ggagagatgt   3300

cgagtgacat ctatgtgaag aggtaggctg ctggccgggc ggggcaacgg cggtgcacta   3360

gggggattgc aaatgggtgt gggccctcgg gctgagtcca gagccccgac cccaggccct   3420

ccgtggtgct gagagcgggg tgaggagtgg gttctccatg tagctccagc cctgacgctc   3480

acccaccccg gccccagctg ggtgaagggg ttggagcatg acaagcagga gacagacgtt   3540

cacttcaact ccctgactgg ggaggggaac ttcaattggc gctttgtgtt ccgctttgac   3600

tacctgccca cggagcggga ggtgagcgtc tggcgcaggt ctggaccctt tgccctggag   3660

gaggcggagt tccggcagcc tgcagtgctg gtcctgcagg tctgggacta tgaccgcatc   3720

tctgccaatg acttccttgg tattacaatg cttagccttc cccaccctca gcccctgcct   3780

ccagccctca cctccgcccc tgcctccagc cctcacttcc gtcccccagt tccctactct   3840

gacccaacct tgaatcttgg gattttggac ccgaggtgtg aaacctttgc tttctggcct   3900

aattactgag ttaattaggc ctagaccaca gtaacctcca ttcccaccca gagtctctga   3960

ttcaactctg atttgaccct agcttgtcac cctgacaccg actccacagc ctttggtcct   4020

tggcactctg atcccgaccc ttggccctct tccactggga agtagcaatg ggtggaccgc   4080

tgggctgtgg tctgggtggt ctatagctgt ggcctgaccg cacactgcaa caactttcaa   4140

tgccccaatt tacaaccttg gtgtgttgcc tcctcacccc tggcacaatg agactttgat   4200

cccatgccta atctggtgtg ctctggactt gcaggatccc tggagttgca gctaccagac   4260

atggtgcgtg gggcccgggg ccccgagctc tgctctgtgc agctggcccg caatggggcc   4320

gggccgaggt gcaatctgtt tcgctgccgc cgcctgaggg gctggtggcc ggtagtgaag   4380

ctgaaggagg cagaggacgt ggagcgggag gcgcaggagg ctcaggctgg caagaagaag   4440

cgaaagcaga ggaggaggaa gggccggcca gaagacctgg agttcacaga catgggtggc   4500

aatgtgtaca tcctcacggg caaggtggag gcagagtttg agctgctgac tgtggaggag   4560

gccgagaaac ggccagtggg gaaggggcgg aagcagccag agcctctgga gaaacccagc   4620

cgccccaaaa cttccttcaa ctggtttgtg aacccgctga agacctttgt cttcttcatc   4680

tggcgccggt actggcgcac cctggtgctg ctgctactgg tgctgctcac cgtcttcctc   4740

ctcctggtct tctacaccat ccctggccag atcagccagg tcatcttccg tcccctccac   4800

aagtgactct cgctgacctt ggacactcac ccagggtgcc aacccttcaa tgcctgctcc   4860

tggaagtctt tcttacccat gtgagctacc ccagagtcta gtgcttcctc tgaataaacc   4920

tatcacagcc actga                                                    4935


<210>  9632
<211>  569
<212>  PRT
<213>  Homo sapiens

<400>  9632

Met Gln Val Leu Glu Gly Arg Ala Glu Pro Glu Pro Pro Gln Ala Gln 
1               5                   10                  15


Gln Gly Ser Thr Leu Ser Arg Leu Thr Arg Lys Lys Lys Lys Lys Ala 
            20                  25                  30


Arg Arg Asp Gln Thr Pro Lys Ala Val Pro Gln His Leu Asp Ala Ser 
        35                  40                  45


Pro Gly Ala Glu Gly Pro Glu Ile Pro Arg Ala Met Glu Val Glu Val 
    50                  55                  60


Glu Glu Leu Leu Pro Leu Pro Glu Asn Val Leu Ala Pro Cys Glu Asp 
65                  70                  75                  80


Phe Leu Leu Phe Gly Val Leu Phe Glu Ala Thr Met Ile Asp Pro Thr 
                85                  90                  95


Val Ala Ser Gln Pro Ile Ser Phe Glu Ile Ser Ile Gly Arg Ala Gly 
            100                 105                 110


Arg Leu Glu Glu Gln Leu Gly Arg Gly Ser Arg Ala Gly Glu Gly Thr 
        115                 120                 125


Glu Gly Ala Ala Val Glu Ala Gln Pro Leu Leu Gly Ala Arg Pro Glu 
    130                 135                 140


Glu Glu Lys Glu Glu Glu Glu Leu Gly Thr His Ala Gln Arg Pro Glu 
145                 150                 155                 160


Pro Met Asp Gly Ser Gly Pro Tyr Phe Cys Leu Pro Leu Cys His Cys 
                165                 170                 175


Lys Pro Cys Met His Val Trp Ser Cys Trp Glu Asp His Thr Trp Arg 
            180                 185                 190


Leu Gln Ser Ser Asn Cys Val Arg Lys Val Ala Glu Arg Leu Asp Gln 
        195                 200                 205


Gly Leu Gln Glu Val Glu Arg Leu Gln Arg Lys Pro Gly Pro Gly Ala 
    210                 215                 220


Cys Ala Gln Leu Lys Gln Ala Leu Glu Val Leu Val Ala Gly Ser Arg 
225                 230                 235                 240


Gln Phe Cys His Gly Ala Glu Arg Arg Thr Met Thr Arg Pro Asn Ala 
                245                 250                 255


Leu Asp Arg Cys Arg Gly Lys Leu Leu Val His Ser Leu Asn Leu Leu 
            260                 265                 270


Ala Lys Gln Gly Leu Arg Leu Leu Arg Gly Leu Arg Arg Arg Asn Val 
        275                 280                 285


Gln Lys Lys Val Ala Leu Ala Lys Lys Leu Leu Ala Lys Leu Arg Phe 
    290                 295                 300


Leu Ala Glu Glu His Asn Phe Asp Glu Asp Glu Met Asp Asp Pro Gly 
305                 310                 315                 320


Asp Ser Asp Gly Val Asn Leu Ile Ser Met Val Gly Glu Ile Gln Asp 
                325                 330                 335


Gln Gly Glu Ala Glu Val Lys Gly Thr Val Ser Pro Lys Lys Ala Val 
            340                 345                 350


Ala Thr Leu Lys Ile Tyr Asn Arg Ser Leu Lys Glu Glu Phe Asn His 
        355                 360                 365


Phe Glu Asp Trp Leu Asn Val Phe Pro Leu Tyr Arg Gly Gln Gly Gly 
    370                 375                 380


Gln Asp Gly Gly Gly Glu Glu Glu Gly Ser Gly His Leu Val Gly Lys 
385                 390                 395                 400


Phe Lys Gly Ser Phe Leu Ile Tyr Pro Glu Ser Glu Ala Val Leu Phe 
                405                 410                 415


Ser Glu Pro Gln Ile Ser Arg Gly Ile Pro Gln Asn Arg Pro Ile Lys 
            420                 425                 430


Leu Leu Val Arg Val Tyr Val Val Lys Leu Arg Asn Leu Cys Lys Ile 
        435                 440                 445


Gln Gly His Glu Asp Phe Cys Leu Phe Ser Ala Ala Thr Asn Leu Ala 
    450                 455                 460


Pro Ala Asp Pro Asn Gly Lys Ala Asp Pro Tyr Val Val Val Ser Ala 
465                 470                 475                 480


Gly Arg Glu Arg Gln Asp Thr Lys Glu Arg Tyr Ile Pro Lys Gln Leu 
                485                 490                 495


Asn Pro Ile Phe Gly Glu Ile Leu Glu Leu Ser Ile Ser Leu Pro Ala 
            500                 505                 510


Glu Thr Glu Leu Thr Val Ala Val Phe Asp His Asp Leu Val Gly Ser 
        515                 520                 525


Asp Asp Leu Ile Gly Glu Thr His Ile Asp Leu Glu Asn Arg Phe Tyr 
    530                 535                 540


Ser His His Arg Ala Asn Cys Gly Leu Ala Ser Gln Tyr Glu Val Trp 
545                 550                 555                 560


Val Gln Gln Gly Pro Gln Glu Pro Phe 
                565


<210>  9633
<211>  1745
<212>  DNA
<213>  Homo sapiens

<400>  9633
tctcggctga ctgcaacctc cacctcctgg gttcaagcga ttctcctgcc tcagcctccc     60

cagtagctgg gattacaggc gtgggccccc atgtccagct aatttttata tttttagtag    120

agacagggtt tcaccatgtt gtccaggctg gtcttgaacc cctgacctca agtgatccac    180

ccacctctgc ctcccaaagt gctgggatta caggtgtgag ccaccatgcc aggccctctt    240

aacctcttca agtctgtttt ctcatctgca aaacagaggt aataagatca gtatcttctt    300

aatggaagca cctggactac atttttttca ttcattgtta tcataaatga ggactaacct    360

gtctcccgtt gggagttttg aacctagacc tcatgtcttc atgacgtcat cactgcccca    420

ggcccagctg tgtccctaca ccagccccag ctgacgcatc ttctttttct gcctgtagag    480

atggttacaa tgcctggcgt gatgcattct ggccttcgca gatcctggcg gggctgtgcc    540

aacgctgtgg cctccctgcc cctgaatacc gagccggtgc tgtcaaggtg ggcagcaaag    600

tcttcctgac accaccggag accctgcccc cagggatctc ttcacatgtg gattgacatc    660

tttcctcaag atgtgcctgc tccaccccca gttgacatca agcctcggca gccaatcagc    720

tatgagctca gagttgtcat ctggaacacg gaggatgtgg ttctggatga cgagaatcca    780

ctcaccggag agatgtcgag tgacatctat gtgaagaggt aggctgctgg ccgggcgggg    840

caacggcggt gcactagggg gattgcaaat gggtgtgggc cctcgggctg agtccagagc    900

cccgacccca ggccctccgt ggtgctgaga gcggggtgag gagtgggttc tccatgtagc    960

tccagccctg acgctcaccc accccggccc cagctgggtg aaggggttgg agcatgacaa   1020

gcaggagaca gacgttcact tcaactccct gactggggag gggaacttca attggcgctt   1080

tgtgttccgc tttgactacc tgcccacgga gcgggaggtg agcgtctggc gcaggtctgg   1140

accctttgcc ctggaggagg cggagttccg gcagcctgca gtgctggtcc tgcaggtctg   1200

ggactatgac cgcatctctg ccaatgactt ccttggtatt acaatgctta gccttcccca   1260

ccctcagccc ctgcctccag ccctcacctc cgcccctgcc tccagccctc acttccgtcc   1320

cccagttccc tactctgacc caaccttgaa tcttgggatt ttggacccga ggtgtgaaac   1380

ctttgctttc tggcctaatt actgagttaa ttaggcctag accacagtaa cctccattcc   1440

cacccagagt ctctgattca actctgattt gaccctagct tgtcaccctg acaccgactc   1500

cacagccttt ggtccttggc actctgatcc cgacccttgg ccctcttcca ctgggaagta   1560

gcaatgggtg gaccgctggg ctgtggtctg ggtggtctat agctgtggcc tgaccgcaca   1620

ctgcaacaac tttcaatgcc ccaatttaca accttggtgt gttgcctcct cacccctggc   1680

acaatgagac tttgatccca tgcctaatct ggtgtgctct ggacttgcag gatccctgga   1740

gttgc                                                               1745


<210>  9634
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  9634

Met Trp Ile Asp Ile Phe Pro Gln Asp Val Pro Ala Pro Pro Pro Val 
1               5                   10                  15


Asp Ile Lys Pro Arg Gln Pro Ile Ser Tyr Glu Leu Arg Val Val Ile 
            20                  25                  30


Trp Asn Thr Glu Asp Val Val Leu Asp Asp Glu Asn Pro Leu Thr Gly 
        35                  40                  45


Glu Met Ser Ser Asp Ile Tyr Val Lys Arg 
    50                  55


<210>  9635
<211>  260
<212>  DNA
<213>  Homo sapiens

<400>  9635
tactgggaag aggaaagtct cctttggatt ctggacatcg ggctgttgct gaagtccttg     60

ccttttagat ctacaacagg tccctgaagg aagaatttaa ccactttgaa gactggctga    120

atgtgtttcc tctgtaccga gggcaagggg gccaggatgg aggtggagaa gaggaaggat    180

ctggacacct tgtgggcaag ttcaagggct ccttcctcat ttaccctgaa tcagaggcag    240

tgttgttctc tgagccccag                                                260


<210>  9636
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  9636

Met Cys Phe Leu Cys Thr Glu Gly Lys Gly Ala Arg Met Glu Val Glu 
1               5                   10                  15


Lys Arg Lys Asp Leu Asp Thr Leu Trp Ala Ser Ser Arg Ala Pro Ser 
            20                  25                  30


Ser Phe Thr Leu Asn Gln Arg Gln Cys Cys Ser Leu Ser 
        35                  40                  45


<210>  9637
<211>  1104
<212>  DNA
<213>  Homo sapiens

<400>  9637
cgcgatttcc agctccttgg ggcgctgagc tgttttggag gcgccccagg tcgtgttcca     60

cagcggcgcg tccgcagctg ctggccaact tcttccgttt cagagcggct tagcccccct    120

cccctgccct cacccccgaa tacttggagg agatcagggt gaggtgcaga gatttaccag    180

cactcgccct ccccacgctc ccctccaaca cgcttctctt gttccccaca gcggggttta    240

accctacctt cggcccggcc tgggtgcccc tctatggctc gccccccggc gcggggctcc    300

gggatagtct tcaaggtctc aacgaaggcg ttggccaagg catttggttc cgcggccgcc    360

ttctgctggc tgtgtccatg caggtgttgg aagggagagc tgaacctgag cctccccagg    420

cccagcaggg gtccacgttg tcccggctca cccgaaagaa gaaaaagaaa gccagaaggg    480

atcagacccc aaaggcggtt ccgcagcact tggacgccag ccccggtgcc gaggggcctg    540

agatcccccg tgccatggag gtggaggtgg aggagctgct gccgctgcca gagaatgtcc    600

tggcgccctg tgaagatttc ctgcttttcg gtgtgctctt cgaggccacc atgatcgacc    660

ccaccgtggc ctcccagccc atcagcttcg agatctccat tggtgtgtgg cctagccgaa    720

cccctgagtg ccatttcaga ccttagaacc ctggaagggg tgttgacttt cagtaagggg    780

caggttctga cttctgttga ggcagaggtg gttgaggggg ggttccagcc ctcagcctgg    840

cgcccactga cccttgctgc tctggggcag gtcgcgcagg ccgtctggag gagcaattgg    900

gccgagggtc cagggctggg gagggaactg agggtgcagc cgtggaggct cagcctctgc    960

tgggagccag gccagaggag gagaaagagg aggaagaact ggggacccat gctcagcggc   1020

ctgagcccat ggacggcagt gggtgagtgc tgccggtggc tggaaggggg ggtttgggag   1080

gtctccagga acccagaatg cccg                                          1104


<210>  9638
<211>  126
<212>  PRT
<213>  Homo sapiens

<400>  9638

Met Ala Arg Pro Pro Ala Arg Gly Ser Gly Ile Val Phe Lys Val Ser 
1               5                   10                  15


Thr Lys Ala Leu Ala Lys Ala Phe Gly Ser Ala Ala Ala Phe Cys Trp 
            20                  25                  30


Leu Cys Pro Cys Arg Cys Trp Lys Gly Glu Leu Asn Leu Ser Leu Pro 
        35                  40                  45


Arg Pro Ser Arg Gly Pro Arg Cys Pro Gly Ser Pro Glu Arg Arg Lys 
    50                  55                  60


Arg Lys Pro Glu Gly Ile Arg Pro Gln Arg Arg Phe Arg Ser Thr Trp 
65                  70                  75                  80


Thr Pro Ala Pro Val Pro Arg Gly Leu Arg Ser Pro Val Pro Trp Arg 
                85                  90                  95


Trp Arg Trp Arg Ser Cys Cys Arg Cys Gln Arg Met Ser Trp Arg Pro 
            100                 105                 110


Val Lys Ile Ser Cys Phe Ser Val Cys Ser Ser Arg Pro Pro 
        115                 120                 125


<210>  9639
<211>  2079
<212>  DNA
<213>  Homo sapiens

<400>  9639
agaagaaagc tggtaggggc tgggagaggg taccacaggg gagtatgatc tacttggggg     60

ccagagaagg ttccctgagg aaatagtacc tgaacttaga cttgaaggat aacagatgtt    120

aactgggagg agagaatgtt ccaggcagag gaaaaggcat atgcaaaagt ccagcgcctt    180

gaaggagcac agctggggtg cctggagtga gatggagctg gaaagatcca ggtggagctt    240

gacctgaagt accagccccc agagggcgct actggagcct ggtcagagga ggactttggg    300

gcacccatcc aggacagctt cgagttaatc atccccaatg tgggcttcca ggaactggag    360

cctggggagg cccagctgga gcggcgggca gtggctctag gccgcaggct agctcgaagt    420

ctaggccagc aggacgatga agagaatgag ctggagcttg agctggagca ggacctggat    480

gatgagcctg acgtggaact ttctggtgtt atgttcagcc ccctcaagag ccgcgccagg    540

gccctggccc atggggatcc cttccaggtg tccagagctc aagacttcca ggtgggagtc    600

actgtgctgg aagcccagaa actggtggga gtcaacatta acccctatgt ggccgtgcaa    660

gtgggggggc agcgccgtgt gaccgccaca cagcgtggga ccagttgccc cttctacaat    720

gagtacttct tgttcgaatt tcatgacacg cggcttcgtc tccaagactt gctgctggag    780

atcacggtga gtggggtagg ggtgaccagt gtccttcaga gaagggggga tgagaaagct    840

gcaggactaa caccaccttc ccccaaggct ttccattcgc agaccctccc ctttatggcc    900

acccggatag gcaccttcag gatggacctg ggcatcatct tggaccagcc aggtatggaa    960

tcgtcccctt attgagactc tgcacggaca agggccctag agattgaccc tgcagtgact   1020

ccgcatggac ccctatacac tcacttcgga gagggccatc tctggcggag gctgaactct   1080

tggcacttcc gcccctccct gctgagccag agaagccctg gccattgtcc gtcactccga   1140

tagcctcacg gccaccctgt gcgtcccgcc ggtcgcccct tacccctggc tcgccccttc   1200

gcccttagat ggccagttct accaaagatg ggttccgctg catgatcccc gagacacccg   1260

cgccgggacc aagggtttca ttaaggtcac cttgtccgtg agggcgcgcg gggacctgcc   1320

ccctccaatg ctacccccgg ccccagggca ctgttcggac atcgagaagt gagccggggt   1380

gaggtgggga ggaggacatg gatccggggg tggccgtggg gcgcggataa ggggaggggc   1440

cgagatccca gtttctcccc ccccgctcgg tgccccctcc cctaggaacc tgctcctgcc   1500

gcgcggggtg cccgccgaga ggccatgggc gcggctccgc gtgcgcctgt accgcgccga   1560

ggggcttccc gcgctgcgcc tggggctgct gggcagcctg gtccgcgccc tgcacgacca   1620

gcgcgtcctg gtggagccct atgtgcgggt gtctttcctg gggcaggagg gcgagacgtc   1680

ggtgagcgcc gaggcggcgg cgcccgaatg gaacgagcag ctgagcttcg tggagctctt   1740

cccgccgctg acgcgcagcc tccgcctgca gctgcgggac gacgcgcccc tggtcgacgc   1800

ggcactcgct acgcacgtgc cggacctgag gcggatctcc catccgggcc gcgcggcggg   1860

gtttaaccct accttcggcc cggcctgggt gcccctctat ggctcgcccc ccggcgcggg   1920

gctccgggat agtcttcaag gtctcaacga aggcgttggc caaggcattt ggttccgcgg   1980

ccgccttctg ctggctgtgt ccatgcaggt gttggaaggg agagctgaac ctgagcctcc   2040

ccaggcccag caggggtcca cgttgtcccg gctcacccg                          2079


<210>  9640
<211>  154
<212>  PRT
<213>  Homo sapiens

<400>  9640

Met Phe Ser Pro Leu Lys Ser Arg Ala Arg Ala Leu Ala His Gly Asp 
1               5                   10                  15


Pro Phe Gln Val Ser Arg Ala Gln Asp Phe Gln Val Gly Val Thr Val 
            20                  25                  30


Leu Glu Ala Gln Lys Leu Val Gly Val Asn Ile Asn Pro Tyr Val Ala 
        35                  40                  45


Val Gln Val Gly Gly Gln Arg Arg Val Thr Ala Thr Gln Arg Gly Thr 
    50                  55                  60


Ser Cys Pro Phe Tyr Asn Glu Tyr Phe Leu Phe Glu Phe His Asp Thr 
65                  70                  75                  80


Arg Leu Arg Leu Gln Asp Leu Leu Leu Glu Ile Thr Val Ser Gly Val 
                85                  90                  95


Gly Val Thr Ser Val Leu Gln Arg Arg Gly Asp Glu Lys Ala Ala Gly 
            100                 105                 110


Leu Thr Pro Pro Ser Pro Lys Ala Phe His Ser Gln Thr Leu Pro Phe 
        115                 120                 125


Met Ala Thr Arg Ile Gly Thr Phe Arg Met Asp Leu Gly Ile Ile Leu 
    130                 135                 140


Asp Gln Pro Gly Met Glu Ser Ser Pro Tyr 
145                 150


<210>  9641
<211>  2038
<212>  DNA
<213>  Homo sapiens

<400>  9641
acaaaaaaac aaagaaaaaa gaaacgaaaa ggcatgaggt ccatgtcctt gaggcctcat     60

cggctggcag ggagcagact ggggtcctgt tcactcccct tgcctccctc ccaccctatc    120

acagctctca ctccctgagg atgcaggatg gaggctgagg cagtcctgcc agcttgcagc    180

tggtggaggc agggagggct gaattgacct ccaggacctt acccctatcc ctcggtcctc    240

tcctccctcc ccacccatga cccccaggcc tgctccctgt gtgtttgact aaagggtagg    300

gattgctaaa cctgctgggt gagtccagtg agtcagaggc gattcaggtg ggcgggctgg    360

tgggcagaag ggcagacggg cagaggaagt gccagtgcca ctgggaccat ggctctgacg    420

gtaacgcgtg caacgactaa cagggctgac cggcacccac gaccgacaag tgaagctcac    480

ctttcgaggc tttacccaga aaacaagaaa aattcactgt ggtccagaag cagatatcgg    540

tgagctgttc cgatggcccc actatggggc tccactggct ggggagtgtc tgtctgtgca    600

ggtggtcaac tgcagccgtg tattcagcct taggcctcta gggaccctgg tgatctccct    660

gcagcagcta cagaatgctg ggcatttggt gctacgggaa gccctagtgg atgagaatct    720

tcaagtgtcc ccgatccagg tggagcttga cctgaagtac cagcccccag agggcgctac    780

tggagcctgg tcagaggagg actttggggc acccatccag gacagcttcg agttaatcat    840

ccccaatgtg ggcttccagg aactggagcc tggggaggcc cagctggagc ggcgggcagt    900

ggctctaggc cgcaggctag ctcgaagtct aggccagcag gacgatgaag agaatgagct    960

ggagcttgag ctggagcagg acctggatga tgagcctgac gtggaacttt ctggtgttat   1020

gttcagcccc ctcaagagcc gcgccagggc cctggcccat ggggatccct tccaggtgtc   1080

cagagctcaa gacttccagg tgggagtcac tgtgctggaa gcccagaaac tggtgggagt   1140

caacattaac ccctatgtgg ccgtgcaagt gggggggcag cgccgtgtga ccgccacaca   1200

gcgtgggacc agttgcccct tctacaatga gtacttcttg ttcgaatttc atgacacgcg   1260

gcttcgtctc caagacttgc tgctggagat cacggctttc cattcgcaga ccctcccctt   1320

tatggccacc cggataggca ccttcaggat ggacctgggc atcatcttgg accagccaga   1380

tggccagttc taccaaagat gggttccgct gcatgatccc cgagacaccc gcgccgggac   1440

caagggtttc attaaggtca ccttgtccgt gagggcgcgc ggggacctgc cccctccaat   1500

gctacccccg gccccagggc actgttcgga catcgagaag aacctgctcc tgccgcgcgg   1560

ggtgcccgcc gagaggccat gggcgcggct ccgcgtgcgc ctgtaccgcg ccgaggggct   1620

tcccgcgctg cgcctggggc tgctgggcag cctggtccgc gccctgcacg accagcgcgt   1680

cctggtggag ccctatgtgc gggtgtcttt cctggggcag gagggcgaga cgtcggtgag   1740

cgccgaggcg gcggcgcccg aatggaacga gcagctgagc ttcgtggagc tcttcccgcc   1800

gctgacgcgc agcctccgcc tgcagctgcg ggacgacgcg cccctggtcg acgcggcact   1860

cgctacgcac gtgccggacc tgaggcggat ctcccatccg ggccgcgcgg cggggtttaa   1920

ccctaccttc ggcccggcct gggtgcccct ctatggctcg ccccccggcg cggggctccg   1980

ggatagtctt caaggtctca acgaaggcgt tggccaaggc atttggttcc gcggccgc     2038


<210>  9642
<211>  339
<212>  PRT
<213>  Homo sapiens

<400>  9642

Met Phe Ser Pro Leu Lys Ser Arg Ala Arg Ala Leu Ala His Gly Asp 
1               5                   10                  15


Pro Phe Gln Val Ser Arg Ala Gln Asp Phe Gln Val Gly Val Thr Val 
            20                  25                  30


Leu Glu Ala Gln Lys Leu Val Gly Val Asn Ile Asn Pro Tyr Val Ala 
        35                  40                  45


Val Gln Val Gly Gly Gln Arg Arg Val Thr Ala Thr Gln Arg Gly Thr 
    50                  55                  60


Ser Cys Pro Phe Tyr Asn Glu Tyr Phe Leu Phe Glu Phe His Asp Thr 
65                  70                  75                  80


Arg Leu Arg Leu Gln Asp Leu Leu Leu Glu Ile Thr Ala Phe His Ser 
                85                  90                  95


Gln Thr Leu Pro Phe Met Ala Thr Arg Ile Gly Thr Phe Arg Met Asp 
            100                 105                 110


Leu Gly Ile Ile Leu Asp Gln Pro Asp Gly Gln Phe Tyr Gln Arg Trp 
        115                 120                 125


Val Pro Leu His Asp Pro Arg Asp Thr Arg Ala Gly Thr Lys Gly Phe 
    130                 135                 140


Ile Lys Val Thr Leu Ser Val Arg Ala Arg Gly Asp Leu Pro Pro Pro 
145                 150                 155                 160


Met Leu Pro Pro Ala Pro Gly His Cys Ser Asp Ile Glu Lys Asn Leu 
                165                 170                 175


Leu Leu Pro Arg Gly Val Pro Ala Glu Arg Pro Trp Ala Arg Leu Arg 
            180                 185                 190


Val Arg Leu Tyr Arg Ala Glu Gly Leu Pro Ala Leu Arg Leu Gly Leu 
        195                 200                 205


Leu Gly Ser Leu Val Arg Ala Leu His Asp Gln Arg Val Leu Val Glu 
    210                 215                 220


Pro Tyr Val Arg Val Ser Phe Leu Gly Gln Glu Gly Glu Thr Ser Val 
225                 230                 235                 240


Ser Ala Glu Ala Ala Ala Pro Glu Trp Asn Glu Gln Leu Ser Phe Val 
                245                 250                 255


Glu Leu Phe Pro Pro Leu Thr Arg Ser Leu Arg Leu Gln Leu Arg Asp 
            260                 265                 270


Asp Ala Pro Leu Val Asp Ala Ala Leu Ala Thr His Val Pro Asp Leu 
        275                 280                 285


Arg Arg Ile Ser His Pro Gly Arg Ala Ala Gly Phe Asn Pro Thr Phe 
    290                 295                 300


Gly Pro Ala Trp Val Pro Leu Tyr Gly Ser Pro Pro Gly Ala Gly Leu 
305                 310                 315                 320


Arg Asp Ser Leu Gln Gly Leu Asn Glu Gly Val Gly Gln Gly Ile Trp 
                325                 330                 335


Phe Arg Gly 



<210>  9643
<211>  1457
<212>  DNA
<213>  Homo sapiens

<400>  9643
cgacttcacg cagggtccgt ggggtccccg cggcgcgcag cggctgaagg aggccccagg     60

gccttggcga ccgcagcggc ggctttagcg tcagtgacta ggcagcaggg ggtcaggatg    120

cggcgaagct cccgcccggg ctcggcctcg tcctcgcgca agcacacgcc caactttttc    180

agcgagaaca gctcaatgag catcacctcg gaggacagca aagggctccg gtcagcggag    240

cccgggcctg gggagcccga gggcagaaga gcccggggcc cgagctgcgg tgagcccgcc    300

ttgagcgcgg gagtgcccgg aggaaccaca tgggcaggaa gctctcagca gaagccagcg    360

cctcggagcc acaactggca gacagcctgt ggcgcggcaa ccgtgagggg cggggcctcg    420

gaaccgactg ggtctccagt agtctctgag gagccgctcg accttctccc gaccctggat    480

ctgaggcagg agatgcctcc cccgcgggtg ttcaagagct ttctgagcct gctcttccag    540

gggctgagcg tgttgttatc cctggcagga gacgtgctgg tcagcatgta cagggaggtc    600

tgttccatcc gcttcctgtt cacggctgtg tcgctgctga gcctctttct gtcagcattc    660

tggctggggc ttctgtacct ggtctctcct ttggagaatg aacctaagga gatgctgact    720

ctaagtgagt accacgagcg cgtgcgctcc caggggcagc agctgcagca gctccaggcc    780

gagctggata aactccacaa ggaggtgtcc actgttcggg cagccaacag cgagagagtg    840

gccaagctcg tgttccagag gctgaatgag gattttgtgc ggaagcccga ctatgctttg    900

agctctgtgg gagcctccat cgacctgcag aagacatccc acgattacgc agacaggaac    960

actgcctact tctggaatcg cttcagcttc tggaactacg cacggccgcc cacggttatc   1020

ctggagcccc acgtgttccc tgggaattgc tgggcttttg aaggcgacca aggccaggtg   1080

gtgatccaac tgccgggccg agtgcagctg agcgacatca ctctgcagca tccaccgccc   1140

agcgtggagc acaccggagg agccaacagc gccccccgcg atttcgcggt ctttggcctc   1200

caggtttatg atgaaactga agtttccttg gggaaattca ccttcgatgt tgagaaatcg   1260

gagattcaga ctttccacct gcagaatgac cccccagctg cctttcccaa ggtgaagatc   1320

cagattctaa gcaactgggg ccacccccgt ttcacgtgct tgtatcgagt ccgtgcccac   1380

ggtgtgcgaa cctcagaggg ggcagagggc agtgcacagg ggccccatta aacatgctga   1440

tttttggagt agaattg                                                  1457


<210>  9644
<211>  437
<212>  PRT
<213>  Homo sapiens

<400>  9644

Met Arg Arg Ser Ser Arg Pro Gly Ser Ala Ser Ser Ser Arg Lys His 
1               5                   10                  15


Thr Pro Asn Phe Phe Ser Glu Asn Ser Ser Met Ser Ile Thr Ser Glu 
            20                  25                  30


Asp Ser Lys Gly Leu Arg Ser Ala Glu Pro Gly Pro Gly Glu Pro Glu 
        35                  40                  45


Gly Arg Arg Ala Arg Gly Pro Ser Cys Gly Glu Pro Ala Leu Ser Ala 
    50                  55                  60


Gly Val Pro Gly Gly Thr Thr Trp Ala Gly Ser Ser Gln Gln Lys Pro 
65                  70                  75                  80


Ala Pro Arg Ser His Asn Trp Gln Thr Ala Cys Gly Ala Ala Thr Val 
                85                  90                  95


Arg Gly Gly Ala Ser Glu Pro Thr Gly Ser Pro Val Val Ser Glu Glu 
            100                 105                 110


Pro Leu Asp Leu Leu Pro Thr Leu Asp Leu Arg Gln Glu Met Pro Pro 
        115                 120                 125


Pro Arg Val Phe Lys Ser Phe Leu Ser Leu Leu Phe Gln Gly Leu Ser 
    130                 135                 140


Val Leu Leu Ser Leu Ala Gly Asp Val Leu Val Ser Met Tyr Arg Glu 
145                 150                 155                 160


Val Cys Ser Ile Arg Phe Leu Phe Thr Ala Val Ser Leu Leu Ser Leu 
                165                 170                 175


Phe Leu Ser Ala Phe Trp Leu Gly Leu Leu Tyr Leu Val Ser Pro Leu 
            180                 185                 190


Glu Asn Glu Pro Lys Glu Met Leu Thr Leu Ser Glu Tyr His Glu Arg 
        195                 200                 205


Val Arg Ser Gln Gly Gln Gln Leu Gln Gln Leu Gln Ala Glu Leu Asp 
    210                 215                 220


Lys Leu His Lys Glu Val Ser Thr Val Arg Ala Ala Asn Ser Glu Arg 
225                 230                 235                 240


Val Ala Lys Leu Val Phe Gln Arg Leu Asn Glu Asp Phe Val Arg Lys 
                245                 250                 255


Pro Asp Tyr Ala Leu Ser Ser Val Gly Ala Ser Ile Asp Leu Gln Lys 
            260                 265                 270


Thr Ser His Asp Tyr Ala Asp Arg Asn Thr Ala Tyr Phe Trp Asn Arg 
        275                 280                 285


Phe Ser Phe Trp Asn Tyr Ala Arg Pro Pro Thr Val Ile Leu Glu Pro 
    290                 295                 300


His Val Phe Pro Gly Asn Cys Trp Ala Phe Glu Gly Asp Gln Gly Gln 
305                 310                 315                 320


Val Val Ile Gln Leu Pro Gly Arg Val Gln Leu Ser Asp Ile Thr Leu 
                325                 330                 335


Gln His Pro Pro Pro Ser Val Glu His Thr Gly Gly Ala Asn Ser Ala 
            340                 345                 350


Pro Arg Asp Phe Ala Val Phe Gly Leu Gln Val Tyr Asp Glu Thr Glu 
        355                 360                 365


Val Ser Leu Gly Lys Phe Thr Phe Asp Val Glu Lys Ser Glu Ile Gln 
    370                 375                 380


Thr Phe His Leu Gln Asn Asp Pro Pro Ala Ala Phe Pro Lys Val Lys 
385                 390                 395                 400


Ile Gln Ile Leu Ser Asn Trp Gly His Pro Arg Phe Thr Cys Leu Tyr 
                405                 410                 415


Arg Val Arg Ala His Gly Val Arg Thr Ser Glu Gly Ala Glu Gly Ser 
            420                 425                 430


Ala Gln Gly Pro His 
        435


<210>  9645
<211>  844
<212>  DNA
<213>  Homo sapiens

<400>  9645
tcggcctccc aaatcgctgg gattacaggc gtgagccacc gcgcccggcc aggagaccaa     60

ctcttgacgg agcctccctg aggggcgggg cttcagaggg cggagctgga gccgggatag    120

ggctgcggtg ggaccaaagc ctgtgagaga cttcccagct gtctggcttg tggactgagc    180

aatctgcggc ccggtctcga ggggaaaata ggtctgtggt ccgcaaggcc ccagtggagc    240

ccttgggttc ccgcagaacc gactgggtct ccagtagtct ctgaggagcc gctcgacctt    300

ctcccgaccc tggatctgag gcaggagatg cctcccccgc gggtgttcaa gagctttctg    360

agcctgctct tccaggggct gagcgtgttg ttatccctgg caggagacgt gctggtcagc    420

atgtacaggg aggtctgttc catccgcttc ctgttcacgg ctgtgtcgct gctgagcctc    480

tttctgtcag cattctggct ggggcttctg tacctggtct ctcctttgga gaatgaacct    540

aaggagatgc tgactctaag gtgaaagagg gcacctaggg tgggaaattg gggggctcaa    600

agttgcttct ttgagaacct tgaaggcgtg ggggcctttg ggaggtgtcc agggggacag    660

ggagccaacc ccacggcgcc cacctcccac ctccagtgag taccacgagc gcgtgcgctc    720

ccaggggcag cagctgcagc agctccaggc cgagctggat aaactccaca aggaggtgtc    780

cactgttcgg gcagccaaca gcgaggtgag ccccggccca ccttggaaac ccctgatgga    840

tccc                                                                 844


<210>  9646
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  9646

Met Pro Pro Pro Arg Val Phe Lys Ser Phe Leu Ser Leu Leu Phe Gln 
1               5                   10                  15


Gly Leu Ser Val Leu Leu Ser Leu Ala Gly Asp Val Leu Val Ser Met 
            20                  25                  30


Tyr Arg Glu Val Cys Ser Ile Arg Phe Leu Phe Thr Ala Val Ser Leu 
        35                  40                  45


Leu Ser Leu Phe Leu Ser Ala Phe Trp Leu Gly Leu Leu Tyr Leu Val 
    50                  55                  60


Ser Pro Leu Glu Asn Glu Pro Lys Glu Met Leu Thr Leu Arg 
65                  70                  75


<210>  9647
<211>  730
<212>  DNA
<213>  Homo sapiens

<400>  9647
agccgggata gggctgcggt gggaccaaag cctgtgagag acttcccagc tgtctggctt     60

gtggactgag caatctgcgg cccggtctcg aggggaaaat aggtctgtgg tccgcaaggc    120

cccagtggag cccttgggtt cccgcagaac cgactgggtc tccagtagtc tctgaggagc    180

cgctcgacct tctcccgacc ctggatctga ggcaggagat gcctcccccg cgggtgttca    240

agagctttct gagcctgctc ttccaggggc tgagcgtgtt gttatccctg gcaggagacg    300

tgctggtcag catgtacagg tcagaggaag ggacgctggc gccccaggaa cagctctttg    360

gagggggtgg ggagcagggc cggaaccttg ctggcgcttg agccgattca gatctgattg    420

agtcatgttg gcaagagctg ggtctaggac cctggggtgg ggactggagg gttgagcagg    480

tcggggcctc agcctccctc cggttcccca gggaggtctg ttccatccgc ttcctgttca    540

cggctgtgtc gctgctgagc ctctttctgt cagcattctg gctggggctt ctgtacctgg    600

tctctccttt ggagaatgaa cctaaggaga tgctgactct aaggtgaaag agggcaccta    660

gggtgggaaa ttggggggct caaagttgct tctttgagaa ccttgaaggc gtgggggcct    720

ttgggaggtg                                                           730


<210>  9648
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  9648

Met Pro Pro Pro Arg Val Phe Lys Ser Phe Leu Ser Leu Leu Phe Gln 
1               5                   10                  15


Gly Leu Ser Val Leu Leu Ser Leu Ala Gly Asp Val Leu Val Ser Met 
            20                  25                  30


Tyr Arg Ser Glu Glu Gly Thr Leu Ala Pro Gln Glu Gln Leu Phe Gly 
        35                  40                  45


Gly Gly Gly Glu Gln Gly Arg Asn Leu Ala Gly Ala 
    50                  55                  60


<210>  9649
<211>  368
<212>  DNA
<213>  Homo sapiens

<400>  9649
gagagacttc ccagctgtct ggcttgtgga ctgagcaatc tgcggcccgg tctcgagggg     60

aaaataggtc tgtggtccgc aaggccccag tggagccctt gggttcccgc agaaccgact    120

gggtctccag tagtctctga ggagccgctc gaccttctcc cgaccctgga tctgaggcag    180

gagatgcctc ccccgcgggt gttcaagagc tttctgagcc tgctcttcca ggggctgagc    240

gtgttgttat ccctggcagg agacgtgctg gtcagcatgt acagggtcct gagacttaag    300

ctccgcccag agccctgcgg gatttctccc ggtgcccacg aagtccatcc caaagcaacc    360

agctccca                                                             368


<210>  9650
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  9650

Met Pro Pro Pro Arg Val Phe Lys Ser Phe Leu Ser Leu Leu Phe Gln 
1               5                   10                  15


Gly Leu Ser Val Leu Leu Ser Leu Ala Gly Asp Val Leu Val Ser Met 
            20                  25                  30


Tyr Arg Val Leu Arg Leu Lys Leu Arg Pro Glu Pro Cys Gly Ile Ser 
        35                  40                  45


Pro Gly Ala His Glu Val His Pro Lys Ala Thr Ser 
    50                  55                  60


<210>  9651
<211>  569
<212>  DNA
<213>  Homo sapiens

<400>  9651
gagacttccc agctgtctgg cttgtggact gagcaatctg cggcccggtc tcgaggggaa     60

aataggtctg tggtccgcaa ggccccagtg gagcccttgg gttcccgcag aaccgactgg    120

gtctccagta gtctctgagg agccgctcga ccttctcccg accctggatc tgaggcagga    180

gatgcctccc ccgcgggtgt tcaagagctt tctgagcctg ctcttccagg ggctgagcgt    240

gttgttatcc ctggcaggag acgtgctggt cagcatgtac aggtcagagg aagggacgct    300

ggcgccccag gaacagctct ttggaggggg tggggagcag ggccggaacc ttgctggcgc    360

ttgagccgat tcagatctga ttgagtcatg ttggcaagag ctgggtctag gaccctgggg    420

tggggactgg agggttgagc aggtcggggc ctcagcctcc ctccggttcc ccagggaggt    480

ctgttccatc cgcttcctgt tcacggctgt gtcgctgctg agcctctttc tgtcaggtga    540

ggggcagtga attccctgga gcccctgcc                                      569


<210>  9652
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  9652

Met Pro Pro Pro Arg Val Phe Lys Ser Phe Leu Ser Leu Leu Phe Gln 
1               5                   10                  15


Gly Leu Ser Val Leu Leu Ser Leu Ala Gly Asp Val Leu Val Ser Met 
            20                  25                  30


Tyr Arg Ser Glu Glu Gly Thr Leu Ala Pro Gln Glu Gln Leu Phe Gly 
        35                  40                  45


Gly Gly Gly Glu Gln Gly Arg Asn Leu Ala Gly Ala 
    50                  55                  60


<210>  9653
<211>  2847
<212>  DNA
<213>  Homo sapiens

<400>  9653
gaatgaatgg ctctggagca cctatgaatt tgaacaataa tctgaatcct atgtttcttg     60

gtccgttgaa tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc    120

ccatcaaccc tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa    180

atgatgtcag agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc    240

atgtaggtcg aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg    300

aagctttgaa acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca    360

cagaaagaca gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt    420

ctggacaaac tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga    480

aaagatcaag gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac    540

catttgaagc agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag    600

atagtattta tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt    660

tcagaaatga ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc    720

gctttattca agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc    780

gaaaaagact gcagaacttc agctatgacc agagggaaat gatactaaat ccagaggggg    840

atgtcaactc tgccaaagtc tgtgcccaca taacaaatat tccattcagc attacaaaga    900

tggatgttct tcagttccta gaaggaatcc cagtggatga aaatgctgta catgttcttg    960

ttgataacaa tgggcaaggt ctaggacagg cattggttca gtttaaaaat gaagatgatg   1020

cacatggccc actgcgtgac cttggttcag ctgtccattt cctgtgacca tctcattgac   1080

aaggacatcg gctccaagtc tgacccactc tgcgtccttt tacaggatgt gggagggggc   1140

agctgggctg agcttggccg gactgaacgg gtgcggaact gctcaagccc tgagttctcc   1200

aagactctac agcttgagta ccgctttgag acagtccaga agctacgctt tggaatctat   1260

gacatagaca acaagacgcc agagctgagg gatgatgact tcctaggggg tgctgagtgt   1320

tccctaggac agattgtgtc cagccaggta ctgactctcc ccttgatgct gaagcctgga   1380

aaacctgctg ggcgggggac catcacggtc tcagctcagg aattaaagga caatcgtgta   1440

gtaaccatgg aggtagaggc cagaaaccta gataagaagg acttcctggg aaaatcagat   1500

ccatttctgg agttcttccg ccagggtgat gggaaatggc acctggtgta cagatctgag   1560

gtcatcaaga acaacctgaa ccctacatgg aagcgtttct cagtccccgt tcagcatttc   1620

tgtggtggga accccagcac acccatccag gtgcaatgct ccgattatga cagtgacggg   1680

tcacatgatc tcatcggtac cttccacacc agcttggccc agctgcaggc agtcccggct   1740

gagtttgaat gcatccaccc tgagaagcag cagaaaaaga aaagctacaa gaactctgga   1800

actatccgtg tcaagatttg tcgggtagaa acagagtact cctttctgga ctatgtgatg   1860

ggaggctgtc agatcaactt cactgtgggc gtggacttca ctggctccaa tggagacccc   1920

tcctcacctg actccctaca ctacctgagt ccaacagggg tcaatgagta cctgatggca   1980

ctgtggagtg tgggcagcgt ggttcaggac tatgactcag acaagctgtt ccctgcattt   2040

ggatttgggg cccaggttcc ccctgactgg caggtctcgc atgaatttgc cttgaatttc   2100

aaccccagta acccctactg tgcaggcatc cagggcattg tggatgccta ccgccaagcc   2160

ctgccccaag ttcgcctcta tggccctacc aactttgcac ccatcatcaa ccatgtggcc   2220

aggtttgcag cccaggctgc acatcagggg actgcctcgc aatacttcat gctgttgctg   2280

ctgactgatg gtgctgtgac ggatgtggaa gccacacgtg aggctgtggt gcgtgcctcg   2340

aacctgccca tgtcagtgat cattgtgggt gtgggtggtg ctgactttga ggccatggag   2400

cagctggacg ctgatggtgg acccctgcat acacgttctg ggcaggctgc tgcccgcgac   2460

attgtgcagt ttgtacccta ccgccggttc cagaatgccc ctcgggaggc attggcacag   2520

accgtgctcg cagaagtgcc cacacaactg gtctcatact tcagggccca gggttgggcc   2580

ccgctcaagc cacttccacc ctcagccaag gatcctgcac aggcccccca ggcctaggtt   2640

cccttggagg ctgtggcaag tcctcaatcc tgtgtcccag aggtccctct gggccacaac   2700

ccaacccttc tcactctcct cagtgctagc actttgtatt ttttgatact tttatacttg   2760

tttctgcttt tgctgctctt gatcccacct ttgctcctga caaccctcat tcaataaaga   2820

ccagtgaaga ccaatgcttt gccacca                                       2847


<210>  9654
<211>  542
<212>  PRT
<213>  Homo sapiens

<400>  9654

Met Lys Met Met His Met Ala His Cys Val Thr Leu Val Gln Leu Ser 
1               5                   10                  15


Ile Ser Cys Asp His Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp 
            20                  25                  30


Pro Leu Cys Val Leu Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu 
        35                  40                  45


Leu Gly Arg Thr Glu Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser 
    50                  55                  60


Lys Thr Leu Gln Leu Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg 
65                  70                  75                  80


Phe Gly Ile Tyr Asp Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp 
                85                  90                  95


Asp Phe Leu Gly Gly Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser 
            100                 105                 110


Gln Val Leu Thr Leu Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly 
        115                 120                 125


Arg Gly Thr Ile Thr Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val 
    130                 135                 140


Val Thr Met Glu Val Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu 
145                 150                 155                 160


Gly Lys Ser Asp Pro Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys 
                165                 170                 175


Trp His Leu Val Tyr Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro 
            180                 185                 190


Thr Trp Lys Arg Phe Ser Val Pro Val Gln His Phe Cys Gly Gly Asn 
        195                 200                 205


Pro Ser Thr Pro Ile Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly 
    210                 215                 220


Ser His Asp Leu Ile Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln 
225                 230                 235                 240


Ala Val Pro Ala Glu Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys 
                245                 250                 255


Lys Lys Ser Tyr Lys Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg 
            260                 265                 270


Val Glu Thr Glu Tyr Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln 
        275                 280                 285


Ile Asn Phe Thr Val Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro 
    290                 295                 300


Ser Ser Pro Asp Ser Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu 
305                 310                 315                 320


Tyr Leu Met Ala Leu Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp 
                325                 330                 335


Ser Asp Lys Leu Phe Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro 
            340                 345                 350


Asp Trp Gln Val Ser His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn 
        355                 360                 365


Pro Tyr Cys Ala Gly Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala 
    370                 375                 380


Leu Pro Gln Val Arg Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile 
385                 390                 395                 400


Asn His Val Ala Arg Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala 
                405                 410                 415


Ser Gln Tyr Phe Met Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp 
            420                 425                 430


Val Glu Ala Thr Arg Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met 
        435                 440                 445


Ser Val Ile Ile Val Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu 
    450                 455                 460


Gln Leu Asp Ala Asp Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala 
465                 470                 475                 480


Ala Ala Arg Asp Ile Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn 
                485                 490                 495


Ala Pro Arg Glu Ala Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr 
            500                 505                 510


Gln Leu Val Ser Tyr Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro 
        515                 520                 525


Leu Pro Pro Ser Ala Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535                 540


<210>  9655
<211>  1846
<212>  DNA
<213>  Homo sapiens

<400>  9655
agcgggccga cggccatttt gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg     60

gaagccgttc gggctggggc tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt    120

cggggtctgg gttctggtgc cgcgcagctt tccccgatgg cccactgcgt gaccttggtt    180

cagctgtcca tttcctgtga ccatctcatt gacaaggaca tcggctccaa gtctgaccca    240

ctctgcgtcc ttttacagga tgtgggaggg ggcagctggg ctgagcttgg ccggactgaa    300

cgggtgcgga actgctcaag ccctgagttc tccaagactc tacagcttga gtaccgcttt    360

gagacagtcc agaagctacg ctttggaatc tatgacatag acaacaagac gccagagctg    420

agggatgatg acttcctagg gggtgctgag tgttccctag gacagattgt gtccagccag    480

gtactgactc tccccttgat gctgaagcct ggaaaacctg ctgggcgggg gaccatcacg    540

gtctcagctc aggaattaaa ggacaatcgt gtagtaacca tggaggtaga ggccagaaac    600

ctagataaga aggacttcct gggaaaatca gatccatttc tggagttctt ccgccagggt    660

gatgggaaat ggcacctggt gtacagatct gaggtcatca agaacaacct gaaccctaca    720

tggaagcgtt tctcagtccc cgttcagcat ttctgtggtg ggaaccccag cacacccatc    780

caggtgcaat gctccgatta tgacagtgac gggtcacatg atctcatcgg taccttccac    840

accagcttgg cccagctgca ggcagtcccg gctgagtttg aatgcatcca ccctgagaag    900

cagcagaaaa agaaaagcta caagaactct ggaactatcc gtgtcaagat ttgtcgggta    960

gaaacagagt actcctttct ggactatgtg atgggaggct gtcagatcaa cttcactgtg   1020

ggcgtggact tcactggctc caatggagac ccctcctcac ctgactccct acactacctg   1080

agtccaacag gggtcaatga gtacctgatg gcactgtgga gtgtgggcag cgtggttcag   1140

gactatgact cagacaagct gttccctgca tttggatttg gggcccaggt tccccctgac   1200

tggcaggtct cgcatgaatt tgccttgaat ttcaacccca gtaaccccta ctgtgcagca   1260

atacttcatg ctgttgctgc tgactgatgg tgctgtgacg gatgtggaag ccacacgtga   1320

ggctgtggtg cgtgcctcga acctgcccat gtcagtgatc attgtgggtg tgggtggtgc   1380

tgactttgag gccatggagc agctggacgc tgatggtgga cccctgcata cacgttctgg   1440

gcaggctgct gcccgcgaca ttgtgcagtt tgtaccctac cgccggttcc agaatgcccc   1500

tcgggaggca ttggcacaga ccgtgctcgc agaagtgccc acacaactgg tctcatactt   1560

cagggcccag ggttgggccc cgctcaagcc acttccaccc tcagccaagg atcctgcaca   1620

ggccccccag gcctaggttc ccttggaggc tgtggcaagt cctcaatcct gtgtcccaga   1680

ggtccctctg ggccacaacc caacccttct cactctcctc agtgctagca ctttgtattt   1740

tttgatactt ttatacttgt ttctgctttt gctgctcttg atcccacctt tgctcctgac   1800

aaccctcatt caataaagac cagtgaagac caatgctttg ccacca                  1846


<210>  9656
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  9656

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Ala 
        355                 360                 365


Ile Leu His Ala Val Ala Ala Asp 
    370                 375


<210>  9657
<211>  1991
<212>  DNA
<213>  Homo sapiens

<400>  9657
cggagccgct gagcgggccg acggccattt tgtgaagcgg cgaaggaggt ggtggctgcg     60

ttgggctccg ggaagccgtt cgggctgggg ctgtcggccg cggggcggag gcactcgcgc    120

ggggggtaat tcggggtctg ggttctggtg ccgcgcagct ttccccgatg gcccactgcg    180

tgaccttggt tcagctgtcc atttcctgtg accatctcat tgacaaggac atcggctcca    240

agtctgaccc actctgcgtc cttttacagg atgtgggagg gggcagctgg gctgagcttg    300

gccggactga acgggtgcgg aactgctcaa gccctgagtt ctccaagact ctacagcttg    360

agtaccgctt tgagacagtc cagaagctac gctttggaat ctatgacata gacaacaaga    420

cgccagagct gagggatgat gacttcctag ggggtgctga gtgttcccta ggacagattg    480

tgtccagcca ggtactgact ctccccttga tgctgaagcc tggaaaacct gctgggcggg    540

ggaccatcac ggtctcagct caggaattaa aggacaatcg tgtagtaacc atggaggtag    600

aggccagaaa cctagataag aaggacttcc tgggaaaatc agatccattt ctggagttct    660

tccgccaggg tgatgggaaa tggcacctgg tgtacagatc tgaggtcatc aagaacaacc    720

tgaaccctac atggaagcgt ttctcagtcc ccgttcagca tttctgtggt gggaacccca    780

gcacacccat ccaggtgcaa tgctccgatt atgacagtga cgggtcacat gatctcatcg    840

gtaccttcca caccagcttg gcccagctgc aggcagtccc ggctgagttt gaatgcatcc    900

accctgagaa gcagcagaaa aagaaaagct acaagaactc tggaactatc cgtgtcaaga    960

tttgtcgggt agaaacagag tactcctttc tggactatgt gatgggaggc tgtcagatca   1020

acttcactgt gggcgtggac ttcactggct ccaatggaga cccctcctca cctgactccc   1080

tacactacct gagtccaaca ggggtcaatg agtacctgat ggcactgtgg agtgtgggca   1140

gcgtggttca ggactatgac tcagacaagc tgttccctgc atttggattt ggggcccagg   1200

ttccccctga ctggcaggtc tcgcatgaat ttgccttgaa tttcaacccc agtaacccct   1260

actgtgcagg catccagggc attgtggatg cctaccgcca agccctgccc caagttcgcc   1320

tctatggccc taccaacttt gcacccatca tcaaccatgt ggccaggttt gcagcccagg   1380

ctgcacatca ggggactgcc tcgcaatact tcatgctgtt gctgctgact gatggtgctg   1440

tgacggatgt ggaagccaca cgtgaggctg tggtgcgtgc ctcgaacctg cccatgtcag   1500

tgatcattgt gggtgtgggt ggtgctgact ttgaggccat ggagcagctg gacgctgatg   1560

gtggacccct gcatacacgt tctgggcagg ctgctgcccg cgacattgtg cagtttgtac   1620

cctaccgccg gttccagaat gcccctcggg aggcattggc acagaccgtg ctcgcagaag   1680

tgcccacaca actggtctca tacttcaggg cccagggttg ggccccgctc aagccacttc   1740

caccctcagc caaggatcct gcacaggccc cccaggccta ggttcccttg gaggctgtgg   1800

caagtcctca atcctgtgtc ccagaggtcc ctctgggcca caacccaacc cttctcactc   1860

tcctcagtgc tagcactttg tattttttga tacttttata cttgtttctg cttttgctgc   1920

tcttgatccc acctttgctc ctgacaaccc tcattcaata aagaccagtg aagaccaatg   1980

ctttgccacc a                                                        1991


<210>  9658
<211>  537
<212>  PRT
<213>  Homo sapiens

<400>  9658

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
        435                 440                 445


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
    450                 455                 460


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
465                 470                 475                 480


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
                485                 490                 495


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
            500                 505                 510


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
        515                 520                 525


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535


<210>  9659
<211>  2076
<212>  DNA
<213>  Homo sapiens

<400>  9659
cggagccgct gagcgggccg acggccattt tgtgaagcgg cgaaggaggt ggtggctgcg     60

ttgggctccg ggaagccgtt cgggctgggg ctgtcggccg cggggcggag gcactcgcgc    120

ggggggtaat tcggggtctg ggttctggtg ccgcgcagct ttccccgtct aaaagttggt    180

tttaattggt tgcccacagg attgacttgg cctctacttc ttgttaagga aattcatctc    240

ttgttttatc agatggccca ctgcgtgacc ttggttcagc tgtccatttc ctgtgaccat    300

ctcattgaca aggacatcgg ctccaagtct gacccactct gcgtcctttt acaggatgtg    360

ggagggggca gctgggctga gcttggccgg actgaacggg tgcggaactg ctcaagccct    420

gagttctcca agactctaca gcttgagtac cgctttgaga cagtccagaa gctacgcttt    480

ggaatctatg acatagacaa caagacgcca gagctgaggg atgatgactt cctagggggt    540

gctgagtgtt ccctaggaca gattgtgtcc agccaggtac tgactctccc cttgatgctg    600

aagcctggaa aacctgctgg gcgggggacc atcacggtct cagctcagga attaaaggac    660

aatcgtgtag taaccatgga ggtagaggcc agaaacctag ataagaagga cttcctggga    720

aaatcagatc catttctgga gttcttccgc cagggtgatg ggaaatggca cctggtgtac    780

agatctgagg tcatcaagaa caacctgaac cctacatgga agcgtttctc agtccccgtt    840

cagcatttct gtggtgggaa ccccagcaca cccatccagg tgcaatgctc cgattatgac    900

agtgacgggt cacatgatct catcggtacc ttccacacca gcttggccca gctgcaggca    960

gtcccggctg agtttgaatg catccaccct gagaagcagc agaaaaagaa aagctacaag   1020

aactctggaa ctatccgtgt caagatttgt cgggtagaaa cagagtactc ctttctggac   1080

tatgtgatgg gaggctgtca gatcaacttc actgtgggcg tggacttcac tggctccaat   1140

ggagacccct cctcacctga ctccctacac tacctgagtc caacaggggt caatgagtac   1200

ctgatggcac tgtggagtgt gggcagcgtg gttcaggact atgactcaga caagctgttc   1260

cctgcatttg gatttggggc ccaggttccc cctgactggc aggtctcgca tgaatttgcc   1320

ttgaatttca accccagtaa cccctactgt gcaggcatcc agggcattgt ggatgcctac   1380

cgccaagccc tgccccaagt tcgcctctat ggccctacca actttgcacc catcatcaac   1440

catgtggcca ggtttgcagc ccaggctgca catcagggga ctgcctcgca atacttcatg   1500

ctgttgctgc tgactgatgg tgctgtgacg gatgtggaag ccacacgtga ggctgtggtg   1560

cgtgcctcga acctgcccat gtcagtgatc attgtgggtg tgggtggtgc tgactttgag   1620

gccatggagc agctggacgc tgatggtgga cccctgcata cacgttctgg gcaggctgct   1680

gcccgcgaca ttgtgcagtt tgtaccctac cgccggttcc agaatgcccc tcgggaggca   1740

ttggcacaga ccgtgctcgc agaagtgccc acacaactgg tctcatactt cagggcccag   1800

ggttgggccc cgctcaagcc acttccaccc tcagccaagg atcctgcaca ggccccccag   1860

gcctaggttc ccttggaggc tgtggcaagt cctcaatcct gtgtcccaga ggtccctctg   1920

ggccacaacc caacccttct cactctcctc agtgctagca ctttgtattt tttgatactt   1980

ttatacttgt ttctgctttt gctgctcttg atcccacctt tgctcctgac aaccctcatt   2040

caataaagac cagtgaagac caatgctttg ccacca                             2076


<210>  9660
<211>  537
<212>  PRT
<213>  Homo sapiens

<400>  9660

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
        435                 440                 445


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
    450                 455                 460


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
465                 470                 475                 480


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
                485                 490                 495


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
            500                 505                 510


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
        515                 520                 525


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535


<210>  9661
<211>  2219
<212>  DNA
<213>  Homo sapiens

<400>  9661
cggagccgct gagcgggccg acggccattt tgtgaagcgg cgaaggaggt ggtggctgcg     60

ttgggctccg ggaagccgtt cgggctgggg ctgtcggccg cggggcggag gcactcgcgc    120

ggggggtaat tcggggtctg ggttctggtg ccgcgcagct ttccccgtct aaaagttggt    180

tttaattggt tgcccacagg attgacttgg cctctacttc ttgttaagga aattcatctc    240

ttgttttatc aggtgtgtgt ggtttcagcg cagcatggct gtggtcatcc gtttgcaagg    300

tctcccaatt gtggcgggga ccatggacat tcgccacttc ttctctggat tgaccattcc    360

tgatgggggc gtgcatattg tagggggtga actggatggc ccactgcgtg accttggttc    420

agctgtccat ttcctgtgac catctcattg acaaggacat cggctccaag tctgacccac    480

tctgcgtcct tttacaggat gtgggagggg gcagctgggc tgagcttggc cggactgaac    540

gggtgcggaa ctgctcaagc cctgagttct ccaagactct acagcttgag taccgctttg    600

agacagtcca gaagctacgc tttggaatct atgacataga caacaagacg ccagagctga    660

gggatgatga cttcctaggg ggtgctgagt gttccctagg acagattgtg tccagccagg    720

tactgactct ccccttgatg ctgaagcctg gaaaacctgc tgggcggggg accatcacgg    780

tctcagctca ggaattaaag gacaatcgtg tagtaaccat ggaggtagag gccagaaacc    840

tagataagaa ggacttcctg ggaaaatcag atccatttct ggagttcttc cgccagggtg    900

atgggaaatg gcacctggtg tacagatctg aggtcatcaa gaacaacctg aaccctacat    960

ggaagcgttt ctcagtcccc gttcagcatt tctgtggtgg gaaccccagc acacccatcc   1020

aggtgcaatg ctccgattat gacagtgacg ggtcacatga tctcatcggt accttccaca   1080

ccagcttggc ccagctgcag gcagtcccgg ctgagtttga atgcatccac cctgagaagc   1140

agcagaaaaa gaaaagctac aagaactctg gaactatccg tgtcaagatt tgtcgggtag   1200

aaacagagta ctcctttctg gactatgtga tgggaggctg tcagatcaac ttcactgtgg   1260

gcgtggactt cactggctcc aatggagacc cctcctcacc tgactcccta cactacctga   1320

gtccaacagg ggtcaatgag tacctgatgg cactgtggag tgtgggcagc gtggttcagg   1380

actatgactc agacaagctg ttccctgcat ttggatttgg ggcccaggtt ccccctgact   1440

ggcaggtctc gcatgaattt gccttgaatt tcaaccccag taacccctac tgtgcaggca   1500

tccagggcat tgtggatgcc taccgccaag ccctgcccca agttcgcctc tatggcccta   1560

ccaactttgc acccatcatc aaccatgtgg ccaggtttgc agcccaggct gcacatcagg   1620

ggactgcctc gcaatacttc atgctgttgc tgctgactga tggtgctgtg acggatgtgg   1680

aagccacacg tgaggctgtg gtgcgtgcct cgaacctgcc catgtcagtg atcattgtgg   1740

gtgtgggtgg tgctgacttt gaggccatgg agcagctgga cgctgatggt ggacccctgc   1800

atacacgttc tgggcaggct gctgcccgcg acattgtgca gtttgtaccc taccgccggt   1860

tccagaatgc ccctcgggag gcattggcac agaccgtgct cgcagaagtg cccacacaac   1920

tggtctcata cttcagggcc cagggttggg ccccgctcaa gccacttcca ccctcagcca   1980

aggatcctgc acaggccccc caggcctagg ttcccttgga ggctgtggca agtcctcaat   2040

cctgtgtccc agaggtccct ctgggccaca acccaaccct tctcactctc ctcagtgcta   2100

gcactttgta ttttttgata cttttatact tgtttctgct tttgctgctc ttgatcccac   2160

ctttgctcct gacaaccctc attcaataaa gaccagtgaa gaccaatgct ttgccacca    2219


<210>  9662
<211>  537
<212>  PRT
<213>  Homo sapiens

<400>  9662

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
        435                 440                 445


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
    450                 455                 460


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
465                 470                 475                 480


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
                485                 490                 495


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
            500                 505                 510


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
        515                 520                 525


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535


<210>  9663
<211>  2092
<212>  DNA
<213>  Homo sapiens

<400>  9663
cggagccgct gagcgggccg acggccattt tgtgaagcgg cgaaggaggt ggtggctgcg     60

ttgggctccg ggaagccgtt cgggctgggg ctgtcggccg cggggcggag gcactcgcgc    120

ggggggtgtg tgtggtttca gcgcagcatg gctgtggtca tccgtttgca aggtctccca    180

attgtggcgg ggaccatgga cattcgccac ttcttctctg gattgaccat tcctgatggg    240

ggcgtgcata ttgtaggggg tgaactggat ggcccactgc gtgaccttgg ttcagctgtc    300

catttcctgt gaccatctca ttgacaagga catcggctcc aagtctgacc cactctgcgt    360

ccttttacag gatgtgggag ggggcagctg ggctgagctt ggccggactg aacgggtgcg    420

gaactgctca agccctgagt tctccaagac tctacagctt gagtaccgct ttgagacagt    480

ccagaagcta cgctttggaa tctatgacat agacaacaag acgccagagc tgagggatga    540

tgacttccta gggggtgctg agtgttccct aggacagatt gtgtccagcc aggtactgac    600

tctccccttg atgctgaagc ctggaaaacc tgctgggcgg gggaccatca cggtctcagc    660

tcaggaatta aaggacaatc gtgtagtaac catggaggta gaggccagaa acctagataa    720

gaaggacttc ctgggaaaat cagatccatt tctggagttc ttccgccagg gtgatgggaa    780

atggcacctg gtgtacagat ctgaggtcat caagaacaac ctgaacccta catggaagcg    840

tttctcagtc cccgttcagc atttctgtgg tgggaacccc agcacaccca tccaggtgca    900

atgctccgat tatgacagtg acgggtcaca tgatctcatc ggtaccttcc acaccagctt    960

ggcccagctg caggcagtcc cggctgagtt tgaatgcatc caccctgaga agcagcagaa   1020

aaagaaaagc tacaagaact ctggaactat ccgtgtcaag atttgtcggg tagaaacaga   1080

gtactccttt ctggactatg tgatgggagg ctgtcagatc aacttcactg tgggcgtgga   1140

cttcactggc tccaatggag acccctcctc acctgactcc ctacactacc tgagtccaac   1200

aggggtcaat gagtacctga tggcactgtg gagtgtgggc agcgtggttc aggactatga   1260

ctcagacaag ctgttccctg catttggatt tggggcccag gttccccctg actggcaggt   1320

ctcgcatgaa tttgccttga atttcaaccc cagtaacccc tactgtgcag gcatccaggg   1380

cattgtggat gcctaccgcc aagccctgcc ccaagttcgc ctctatggcc ctaccaactt   1440

tgcacccatc atcaaccatg tggccaggtt tgcagcccag gctgcacatc aggggactgc   1500

ctcgcaatac ttcatgctgt tgctgctgac tgatggtgct gtgacggatg tggaagccac   1560

acgtgaggct gtggtgcgtg cctcgaacct gcccatgtca gtgatcattg tgggtgtggg   1620

tggtgctgac tttgaggcca tggagcagct ggacgctgat ggtggacccc tgcatacacg   1680

ttctgggcag gctgctgccc gcgacattgt gcagtttgta ccctaccgcc ggttccagaa   1740

tgcccctcgg gaggcattgg cacagaccgt gctcgcagaa gtgcccacac aactggtctc   1800

atacttcagg gcccagggtt gggccccgct caagccactt ccaccctcag ccaaggatcc   1860

tgcacaggcc ccccaggcct aggttccctt ggaggctgtg gcaagtcctc aatcctgtgt   1920

cccagaggtc cctctgggcc acaacccaac ccttctcact ctcctcagtg ctagcacttt   1980

gtattttttg atacttttat acttgtttct gcttttgctg ctcttgatcc cacctttgct   2040

cctgacaacc ctcattcaat aaagaccagt gaagaccaat gctttgccac ca           2092


<210>  9664
<211>  537
<212>  PRT
<213>  Homo sapiens

<400>  9664

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
        435                 440                 445


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
    450                 455                 460


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
465                 470                 475                 480


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
                485                 490                 495


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
            500                 505                 510


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
        515                 520                 525


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535


<210>  9665
<211>  1979
<212>  DNA
<213>  Homo sapiens

<400>  9665
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggaggt ggtggctgcg ttgggctccg ggaagccgtt cgggctgggg    120

ctgtcggccg cggggcggag gcactcgcgc gggggatggc ccactgcgtg accttggttc    180

agctgtccat ttcctgtgac catctcattg acaaggacat cggctccaag tctgacccac    240

tctgcgtcct tttacaggat gtgggagggg gcagctgggc tgagcttggc cggactgaac    300

gggtgcggaa ctgctcaagc cctgagttct ccaagactct acagcttgag taccgctttg    360

agacagtcca gaagctacgc tttggaatct atgacataga caacaagacg ccagagctga    420

gggatgatga cttcctaggg ggtgctgagt gttccctagg acagattgtg tccagccagg    480

tactgactct ccccttgatg ctgaagcctg gaaaacctgc tgggcggggg accatcacgg    540

tctcagctca ggaattaaag gacaatcgtg tagtaaccat ggaggtagag gccagaaacc    600

tagataagaa ggacttcctg ggaaaatcag atccatttct ggagttcttc cgccagggtg    660

atgggaaatg gcacctggtg tacagatctg aggtcatcaa gaacaacctg aaccctacat    720

ggaagcgttt ctcagtcccc gttcagcatt tctgtggtgg gaaccccagc acacccatcc    780

aggtgcaatg ctccgattat gacagtgacg ggtcacatga tctcatcggt accttccaca    840

ccagcttggc ccagctgcag gcagtcccgg ctgagtttga atgcatccac cctgagaagc    900

agcagaaaaa gaaaagctac aagaactctg gaactatccg tgtcaagatt tgtcgggtag    960

aaacagagta ctcctttctg gactatgtga tgggaggctg tcagatcaac ttcactgtgg   1020

gcgtggactt cactggctcc aatggagacc cctcctcacc tgactcccta cactacctga   1080

gtccaacagg ggtcaatgag tacctgatgg cactgtggag tgtgggcagc gtggttcagg   1140

actatgactc agacaagctg ttccctgcat ttggatttgg ggcccaggtt ccccctgact   1200

ggcaggtctc gcatgaattt gccttgaatt tcaaccccag taacccctac tgtgcaggca   1260

tccagggcat tgtggatgcc taccgccaag ccctgcccca agttcgcctc tatggcccta   1320

ccaactttgc acccatcatc aaccatgtgg ccaggtttgc agcccaggct gcacatcagg   1380

ggactgcctc gcaatacttc atgctgttgc tgctgactga tggtgctgtg acggatgtgg   1440

aagccacacg tgaggctgtg gtgcgtgcct cgaacctgcc catgtcagtg atcattgtgg   1500

gtgtgggtgg tgctgacttt gaggccatgg agcagctgga cgctgatggt ggacccctgc   1560

atacacgttc tgggcaggct gctgcccgcg acattgtgca gtttgtaccc taccgccggt   1620

tccagaatgc ccctcgggag gcattggcac agaccgtgct cgcagaagtg cccacacaac   1680

tggtctcata cttcagggcc cagggttggg ccccgctcaa gccacttcca ccctcagcca   1740

aggatcctgc acaggccccc caggcctagg ttcccttgga ggctgtggca agtcctcaat   1800

cctgtgtccc agaggtccct ctgggccaca acccaaccct tctcactctc ctcagtgcta   1860

gcactttgta ttttttgata cttttatact tgtttctgct tttgctgctc ttgatcccac   1920

ctttgctcct gacaaccctc attcaataaa gaccagtgaa gaccaatgct ttgccacca    1979


<210>  9666
<211>  537
<212>  PRT
<213>  Homo sapiens

<400>  9666

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
        435                 440                 445


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
    450                 455                 460


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
465                 470                 475                 480


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
                485                 490                 495


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
            500                 505                 510


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
        515                 520                 525


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
    530                 535


<210>  9667
<211>  1737
<212>  DNA
<213>  Homo sapiens

<400>  9667
ctatgttgcc taagctggcc ttgaacccct gggctcaagc agtcctccca cctcagcctc     60

gtgagtagct gggactacag gcacatgcca ctgtgcctgg ctatactctc tagttttaac    120

atccattgat gatccttgcc tgaatcagtc atttctgtga ttgtcaaatg attgtgtaat    180

tcttcctttt acatttatta ggagctttcc cttctccctc agtaattaat ccatagtacg    240

gatccttatt gtatcaaatg gatcattatt aaataggtta taatctgatg ctcaaactct    300

cctggatttg tccaggagaa tccctctcat ctgggtgcta attcaagctg tgatttaggg    360

caagtcccct cctctctttg aaccttagtt tcctcatgtg taggagacag ttaagtaccc    420

tggtttacaa gggtgaatga atgaaatgca cccaggttcc gagatctcct gggctgggat    480

ggggtgattt caggactggt gtagtcctga gaggtccagg attttacggt atttcttgct    540

ctcctctgca ggcatccagg gcattgtgga tgcctaccgc caagccctgc cccaagttcg    600

cctctatggc cctaccaact ttgcacccat catcaaccat gtggccaggt ttgcagccca    660

ggctgcacat caggggactg cctcggtgag agtcgtgggt ggcagtggca gtggtggcaa    720

tcaagggctt ccttgagggt tatggaacaa aggacttttt tttttttttt tttttttgag    780

atggactctt gctctgtcac ccaggctgga gtgcagtgac gcgatctcag ctcactgcaa    840

cctgcacctc ctgggttcaa gtgattctcc tgcctcagcc ttcctagtag cttggattac    900

aggcgtgtgc caccatgccc agctaatttt tatattttta gtagagacgg gctttcacca    960

tgttggctgg ggtggtcaca aactcctgac ctcaagtgat ccgcctgcct tagcctccca   1020

aagtgctggg attacaggtg tgagccatcg cacccggcct gtaacaaggg acttcttatg   1080

agtgtgggga tgtgtggctg gggtgtttgc aggggtttag gaggaggatc tgcttcagga   1140

catgaatggg cttgtcccca gcaatacttc atgctgttgc tgctgactga tggtgctgtg   1200

acggatgtgg aagccacacg tgaggctgtg gtgcgtgcct cgaacctgcc catgtcagtg   1260

atcattgtgg gtgtgggtgg tgctgacttt gaggccatgg agcagctgga cgctgatggt   1320

ggacccctgc atacacgttc tgggcaggct gctgcccgcg acattgtgca gtttgtaccc   1380

taccgccggt tccagaatgc ccctcgggag gcattggcac agaccgtgct cgcagaagtg   1440

cccacacaac tggtctcata cttcagggcc cagggttggg ccccgctcaa gccacttcca   1500

ccctcagcca aggatcctgc acaggccccc caggcctagg ttcccttgga ggctgtggca   1560

agtcctcaat cctgtgtccc agaggtccct ctgggccaca acccaaccct tctcactctc   1620

ctcagtgcta gcactttgta ttttttgata cttttatact tgtttctgct tttgctgctc   1680

ttgatcccac ctttgctcct gacaaccctc attcaataaa gaccagtgaa gaccaat      1737


<210>  9668
<211>  153
<212>  PRT
<213>  Homo sapiens

<400>  9668

Met Ser Val Gly Met Cys Gly Trp Gly Val Cys Arg Gly Leu Gly Gly 
1               5                   10                  15


Gly Ser Ala Ser Gly His Glu Trp Ala Cys Pro Gln Gln Tyr Phe Met 
            20                  25                  30


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
        35                  40                  45


Glu Ala Val Val Arg Ala Ser Asn Leu Pro Met Ser Val Ile Ile Val 
    50                  55                  60


Gly Val Gly Gly Ala Asp Phe Glu Ala Met Glu Gln Leu Asp Ala Asp 
65                  70                  75                  80


Gly Gly Pro Leu His Thr Arg Ser Gly Gln Ala Ala Ala Arg Asp Ile 
                85                  90                  95


Val Gln Phe Val Pro Tyr Arg Arg Phe Gln Asn Ala Pro Arg Glu Ala 
            100                 105                 110


Leu Ala Gln Thr Val Leu Ala Glu Val Pro Thr Gln Leu Val Ser Tyr 
        115                 120                 125


Phe Arg Ala Gln Gly Trp Ala Pro Leu Lys Pro Leu Pro Pro Ser Ala 
    130                 135                 140


Lys Asp Pro Ala Gln Ala Pro Gln Ala 
145                 150


<210>  9669
<211>  1799
<212>  DNA
<213>  Homo sapiens

<400>  9669
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggaggt ggtggctgcg ttgggctccg ggaagccgtt cgggctgggg    120

ctgtcggccg cggggcggag gcactcgcgc gggggatggc ccactgcgtg accttggttc    180

agctgtccat ttcctgtgac catctcattg acaaggacat cggctccaag tctgacccac    240

tctgcgtcct tttacaggat gtgggagggg gcagctgggc tgagcttggc cggactgaac    300

gggtgcggaa ctgctcaagc cctgagttct ccaagactct acagcttgag taccgctttg    360

agacagtcca gaagctacgc tttggaatct atgacataga caacaagacg ccagagctga    420

gggatgatga cttcctaggg ggtgctgagt gttccctagg acagattgtg tccagccagg    480

tactgactct ccccttgatg ctgaagcctg gaaaacctgc tgggcggggg accatcacgg    540

tctcagctca ggaattaaag gacaatcgtg tagtaaccat ggaggtagag gccagaaacc    600

tagataagaa ggacttcctg ggaaaatcag atccatttct ggagttcttc cgccagggtg    660

atgggaaatg gcacctggtg tacagatctg aggtcatcaa gaacaacctg aaccctacat    720

ggaagcgttt ctcagtcccc gttcagcatt tctgtggtgg gaaccccagc acacccatcc    780

aggtgcaatg ctccgattat gacagtgacg ggtcacatga tctcatcggt accttccaca    840

ccagcttggc ccagctgcag gcagtcccgg ctgagtttga atgcatccac cctgagaagc    900

agcagaaaaa gaaaagctac aagaactctg gaactatccg tgtcaagatt tgtcgggtag    960

aaacagagta ctcctttctg gactatgtga tgggaggctg tcagatcaac ttcactgtgg   1020

gcgtggactt cactggctcc aatggagacc cctcctcacc tgactcccta cactacctga   1080

gtccaacagg ggtcaatgag tacctgatgg cactgtggag tgtgggcagc gtggttcagg   1140

actatgactc agacaagctg ttccctgcat ttggatttgg ggcccaggtt ccccctgact   1200

ggcaggtctc gcatgaattt gccttgaatt tcaaccccag taacccctac tgtgcaggca   1260

tccagggcat tgtggatgcc taccgccaag ccctgcccca agttcgcctc tatggcccta   1320

ccaactttgc acccatcatc aaccatgtgg ccaggtttgc agcccaggct gcacatcagg   1380

ggactgcctc gcaatacttc atgctgttgc tgctgactga tggtgctgtg acggatgtgg   1440

aagccacacg tgaggctgtg gcccctcggg aggcattggc acagaccgtg ctcgcagaag   1500

tgcccacaca actggtctca tacttcaggg cccagggttg ggccccgctc aagccacttc   1560

caccctcagc caaggatcct gcacaggccc cccaggccta ggttcccttg gaggctgtgg   1620

caagtcctca atcctgtgtc ccagaggtcc ctctgggcca caacccaacc cttctcactc   1680

tcctcagtgc tagcactttg tattttttga tacttttata cttgtttctg cttttgctgc   1740

tcttgatccc acctttgctc ctgacaaccc tcattcaata aagaccagtg aagaccaat    1799


<210>  9670
<211>  481
<212>  PRT
<213>  Homo sapiens

<400>  9670

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Ser Ala Gln Glu Leu Lys Asp Asn Arg Val Val Thr Met Glu Val 
    130                 135                 140


Glu Ala Arg Asn Leu Asp Lys Lys Asp Phe Leu Gly Lys Ser Asp Pro 
145                 150                 155                 160


Phe Leu Glu Phe Phe Arg Gln Gly Asp Gly Lys Trp His Leu Val Tyr 
                165                 170                 175


Arg Ser Glu Val Ile Lys Asn Asn Leu Asn Pro Thr Trp Lys Arg Phe 
            180                 185                 190


Ser Val Pro Val Gln His Phe Cys Gly Gly Asn Pro Ser Thr Pro Ile 
        195                 200                 205


Gln Val Gln Cys Ser Asp Tyr Asp Ser Asp Gly Ser His Asp Leu Ile 
    210                 215                 220


Gly Thr Phe His Thr Ser Leu Ala Gln Leu Gln Ala Val Pro Ala Glu 
225                 230                 235                 240


Phe Glu Cys Ile His Pro Glu Lys Gln Gln Lys Lys Lys Ser Tyr Lys 
                245                 250                 255


Asn Ser Gly Thr Ile Arg Val Lys Ile Cys Arg Val Glu Thr Glu Tyr 
            260                 265                 270


Ser Phe Leu Asp Tyr Val Met Gly Gly Cys Gln Ile Asn Phe Thr Val 
        275                 280                 285


Gly Val Asp Phe Thr Gly Ser Asn Gly Asp Pro Ser Ser Pro Asp Ser 
    290                 295                 300


Leu His Tyr Leu Ser Pro Thr Gly Val Asn Glu Tyr Leu Met Ala Leu 
305                 310                 315                 320


Trp Ser Val Gly Ser Val Val Gln Asp Tyr Asp Ser Asp Lys Leu Phe 
                325                 330                 335


Pro Ala Phe Gly Phe Gly Ala Gln Val Pro Pro Asp Trp Gln Val Ser 
            340                 345                 350


His Glu Phe Ala Leu Asn Phe Asn Pro Ser Asn Pro Tyr Cys Ala Gly 
        355                 360                 365


Ile Gln Gly Ile Val Asp Ala Tyr Arg Gln Ala Leu Pro Gln Val Arg 
    370                 375                 380


Leu Tyr Gly Pro Thr Asn Phe Ala Pro Ile Ile Asn His Val Ala Arg 
385                 390                 395                 400


Phe Ala Ala Gln Ala Ala His Gln Gly Thr Ala Ser Gln Tyr Phe Met 
                405                 410                 415


Leu Leu Leu Leu Thr Asp Gly Ala Val Thr Asp Val Glu Ala Thr Arg 
            420                 425                 430


Glu Ala Val Ala Pro Arg Glu Ala Leu Ala Gln Thr Val Leu Ala Glu 
        435                 440                 445


Val Pro Thr Gln Leu Val Ser Tyr Phe Arg Ala Gln Gly Trp Ala Pro 
    450                 455                 460


Leu Lys Pro Leu Pro Pro Ser Ala Lys Asp Pro Ala Gln Ala Pro Gln 
465                 470                 475                 480


Ala 



<210>  9671
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  9671
agtctgaact tatgttgaaa tacaaaatta aaattttaaa acccagatca gatcaggtca     60

ggtcagattt tccacttcag cttgtgcccc cttgggggta ctggggagtc aaaaggtttg    120

gccctaaaca aaagggcttg gtggactctg gcaaaatgca ccctgcaagg aggcaaacaa    180

ggcttccact gatgctcaag taagtacctg ttagcttcta ggcaaagata ataacgataa    240

tataacagat accatttttc ggagaacact tagtaagtac caggcttact gctttacttg    300

tatcctctcc ttgagtactc aatttcctat gtttagtctt atgaaaccaa agcacacaga    360

gattaagcaa cctgccccaa gtcatgtggc atcatttttt tttttttttg agataggttc    420

tcactctatc acccaggtct ttctcaaaaa ataaattaaa ctaaaattaa ataaaatcca    480

ccctctggac aatgaaggca ggtatctgcc cccactctcc cttttactca tgcaggcttg    540

cccctctttg tgtggacaga cc                                             562


<210>  9672
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9672

Met Phe Ser Leu Met Lys Pro Lys His Thr Glu Ile Lys Gln Pro Ala 
1               5                   10                  15


Pro Ser His Val Ala Ser Phe Phe Phe Phe Phe Glu Ile Gly Ser His 
            20                  25                  30


Ser Ile Thr Gln Val Phe Leu Lys Lys 
        35                  40


<210>  9673
<211>  581
<212>  DNA
<213>  Homo sapiens

<400>  9673
attttgtgaa gcggcgaagg aggtggtggc tgcgttgggc tccgggaagc cgttcgggct     60

ggggctgtcg gccgcggggc ggaggcactc gcgcgggggg taattcgggg tctgggttct    120

ggtgccgcgc agctttcccc gatggcccac tgcgtgacct tggttcagct gtccatttcc    180

tgtgaccatc tcattgacaa ggacatcggc tccaagtctg acccactctg cgtcctttta    240

caggatgtgg gagggggcag ctgggctgag cttggccgga ctgaacgggt gcggaactgc    300

tcaagccctg agttctccaa gactctacag cttgagtacc gctttgagac agtccagaag    360

ctacgctttg gaatctatga catagacaac aagacgccag agctgaggga tgatgacttc    420

ctagggggtg ctgagtgttc cctaggacag attgtgtcca gccaggtact gactctcccc    480

ttgatgctga agcctggaaa acctgctggg cgggggacca tcacggtaag gaacccagca    540

agggttgagg agggacttaa catcaatgaa ttcatgaggt g                        581


<210>  9674
<211>  145
<212>  PRT
<213>  Homo sapiens

<400>  9674

Met Ala His Cys Val Thr Leu Val Gln Leu Ser Ile Ser Cys Asp His 
1               5                   10                  15


Leu Ile Asp Lys Asp Ile Gly Ser Lys Ser Asp Pro Leu Cys Val Leu 
            20                  25                  30


Leu Gln Asp Val Gly Gly Gly Ser Trp Ala Glu Leu Gly Arg Thr Glu 
        35                  40                  45


Arg Val Arg Asn Cys Ser Ser Pro Glu Phe Ser Lys Thr Leu Gln Leu 
    50                  55                  60


Glu Tyr Arg Phe Glu Thr Val Gln Lys Leu Arg Phe Gly Ile Tyr Asp 
65                  70                  75                  80


Ile Asp Asn Lys Thr Pro Glu Leu Arg Asp Asp Asp Phe Leu Gly Gly 
                85                  90                  95


Ala Glu Cys Ser Leu Gly Gln Ile Val Ser Ser Gln Val Leu Thr Leu 
            100                 105                 110


Pro Leu Met Leu Lys Pro Gly Lys Pro Ala Gly Arg Gly Thr Ile Thr 
        115                 120                 125


Val Arg Asn Pro Ala Arg Val Glu Glu Gly Leu Asn Ile Asn Glu Phe 
    130                 135                 140


Met 
145


<210>  9675
<211>  4759
<212>  DNA
<213>  Homo sapiens

<400>  9675
tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc ccatcaaccc     60

tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa atgatgtcag    120

agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc atgtaggtcg    180

aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg aagctttgaa    240

acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca cagaaagaca    300

gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt ctggacaaac    360

tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga aaagatcaag    420

gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac catttgaagc    480

agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag atagtattta    540

tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt tcagaaatga    600

ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc gctttattca    660

agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc gaaaaagatg    720

tttacagaag actcactcac caggataaac attgctgtat gttacagtaa agctatctgg    780

agagaacaca taaatgattt tggcatacca ttagagaaac catttgtaaa actcaaatga    840

ccacataaag cttatcaagg agtctagatt ggttttgttt tataccatat gggatgaaga    900

aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc cagctgctga aaatagaagt    960

tggctactct cagaatttgg tttaaagctg gacagatttg ctttgttata gggtaaagct   1020

ttgtctaaag tcctcatttt cttttaaaat tgaataaaat ttctgtatac agattcattg   1080

tatgtacctt tattgcttct taagggtcct tgctgtatag acagtcctgc ttcagaagtt   1140

gctgctttgt ttgtctaatt gactcatttg taaatgagca gaactgtttt gttggttttt   1200

ttccctaaat ataaaagtcc acacttcgtt tgtgctataa cctcaaactt tgatttctaa   1260

tgtcacactt aaaactgtgt ggaataagac ttttgccata aaaataaact atggagtcct   1320

ttatctacca gagccttttt ggtttgaccg ccacgattta ggttagtcag tttaaaaatt   1380

gttcatgttg tttggatggt atcgaaaacc agaaaccact tttaataatg tgtttaagat   1440

acttgatttg aagtcctttt catatggact aattgtagta tcaatttcct cctgtcccga   1500

ttatgtgaaa ttttggcctt taaacaaaga ggggcccatt cataagaaag tgttatatct   1560

aggtttttaa aactgaagtt gaaattatct ttgttagcag tagtagtata gaataaaaga   1620

tccgtatgct ggttcgtaga ttgatacgtg ttagtcctgt tatttggagg ctttttggca   1680

tagttgttcg atcaggagcc tgtttactaa aagtcttcat acagagtaca agtgcagccg   1740

ccagaggaga aaattgagat tcttgaccct ttcatactct tttctttggt attcaggaca   1800

ctaaggcagg aggaccacat gagttctggt tggtaagtgt ccttgtcatg aaaacacttg   1860

ccttacaagg ctctaattat gatttcccta gtcagtgctc tgaagatgtg tcacattata   1920

ttataaacaa tacggaaggg gagataggtg agatgatatg aaaaacaaat tttctcactg   1980

tcataaaagg ctctaattat ggttactttc cttgtgatga aaaacttggc cttacagggc   2040

tctagttatg gttactttcc ctagtcaatg ctctgaaaat gtgtcacatt ataaacaata   2100

cagaaggaga gatagatgag agatcatgaa aaccaaattt tatcttttac atggcccctt   2160

tgtcttcgtt tgaaacatcc ccaacatttc ctacaaatca gcgtagttac aaaggggtca   2220

gtcttttaaa ataagtattt cctattaaac tatatatata tacagtgcct ttttggtgtt   2280

gtgagtcagt ggaacactga aatacagcgg ttgtgtaatt taagagtggc aacagtttca   2340

tttgataaga tttgaaaagg ctttttatca ctacaatctt agaggattga cagtacagga   2400

tttttgttta agagaaggat tgtttagact caagaggtga ctatgttgtg ggtcttttga   2460

taattcatga atacagattt gctttgaccg atcactagat actgcctcct caatttcaaa   2520

agcaatataa cgtttgtata tgctgtttaa tttaagttaa tgttaagtaa tcatttctca   2580

ttccaaagac aatgcaaaaa acttcagcac tgcttgagag ttgtatttca gccacagata   2640

ttttctccat tggaaagcta ttttcatttt agaaaaatgg gttgtttgaa gatgaaagtc   2700

ttttatcttt tttcacaatt tattttggtt atatgttcgt acattcttat taaatatttc   2760

atacacttta ttgcaactac tttgttattt ctacatctta gataaatgct gaaaaggaaa   2820

acgatttcat tgttcatcta attaaataaa ttaaaagagc ggtttgtgta gaaattggag   2880

agaactatgt tttatatgaa tcacaacagt gctcgttgtg gactgtaatt aaatgctttg   2940

ccctctggaa cttgattttt gtgtatctga gatttattaa cagtgctaac tgctaaggat   3000

actgtttatc ttgttctggg cattggagtt tcagttttta aaaaattctt gaaaatgtat   3060

tctgtgaaac tactcatacc tctcttcctg cgaattttct cctaagaact aggtttgggg   3120

tagaaatgaa ttgacattat tttctcattt gctttgtatg gtatgaagga tttgtaaagc   3180

tttgctcaaa gttgtgtgca tttgtaaaca ctatcatgat attttcaatt ttatgtgtaa   3240

attttattgt ctgtttttgg tgactctgac attaatggaa gagaatattt tccattagat   3300

ttaatttttt ttcctctccc ttctgatttt ttttttattg gtgttcattt ttcttttgat   3360

ttaaaggatt agagaaatct acaaatgtat gtcataaata agcaaatttg taaacttttc   3420

tgaactttag tgaaacattt agttcacaag cataatttgg aggtgtgttc tgtgtttaca   3480

cagtagtttg gatgtacaat tattattagt ggctttttaa aaaatgaaac agtgttaagt   3540

gaaatgtagt tcctagcttt gtactccaag ttgtcaaagc atcaacaatg aaaattcgat   3600

taggaaactt tatttaaaat ttcaggtagt aatattcagt gtagttaagg ccagtcttaa   3660

cccactggat gaaaatctag gactgtatgg aagtaagcaa acattacatt tttaggtgga   3720

aatagtcagc cttgcataaa aacaaggatg cgtgaaagcc ttaaattcca gctccctttt   3780

actggagtct gtggttgtgt acaggtatgg gccaagtgta aaatctcatc aattttaaga   3840

acactcggga aatgagtaaa gaaaatgtaa aattgctgct agtcaaatct tttggaaaga   3900

atttctggaa gtggtcactt taaaaattat tttccaccct tgcaaaattg ccacatttaa   3960

attgttttac tggcagttct atagtagtcc agactttaga aaccaaacac aacaaaatgg   4020

cttgttgcca atatggccac aacattgcca gcaaatactg ccttggcatc actcagcaga   4080

ggtttttgtt tataaagatg aagtcttgaa tactgttcaa taaacttgtc aaaaaataaa   4140

acaggctgat gcttttaatg ctttaactgc acaaaagtac tttactgagc tataatatta   4200

tcttgtcagg gtttttgttt tgttttgttt ttaaacctga aaatattttg tgcctttgga   4260

gaggtagatt tggtaatctt ggagaggtaa aaattgttgc ttatccttgc ctgctaatgc   4320

tgaagtgtca agagaagagg atacttggaa cagcagggag gaaacttgat tcaagtccat   4380

agtatccacc ttttcagaat tttatgtgta tgatgtgttg gcaaacaaag cccttaaatg   4440

ttgaaaactt tttatcttga aagagtttag cttgtattag aatttggata cccagtgtgt   4500

tttagagggg gctagacata taattccagg tagtagctga gccattatta aataatcggg   4560

atttgactaa gcaatggaca aatcactgag tgaaatcagc tgcctacaga tatccaaaat   4620

ggcttttacc atctgaaagg ggtggactgt gtgataatat gtctcctttt cttgttcagg   4680

agagatcagt tatgtaattc attgttacct gctttccagt gttttacagc aagaaatagt   4740

ttatcaacta tgtgcatca                                                4759


<210>  9676
<211>  242
<212>  PRT
<213>  Homo sapiens

<400>  9676

Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp 
1               5                   10                  15


Leu Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp 
            20                  25                  30


Val Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu 
        35                  40                  45


Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu 
    50                  55                  60


Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met 
65                  70                  75                  80


Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val 
                85                  90                  95


Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly 
            100                 105                 110


Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser 
        115                 120                 125


Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys 
    130                 135                 140


Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile 
145                 150                 155                 160


Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala 
                165                 170                 175


Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg 
            180                 185                 190


Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met 
        195                 200                 205


Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu 
    210                 215                 220


Glu Lys Ile Asp Met Ile Arg Lys Arg Cys Leu Gln Lys Thr His Ser 
225                 230                 235                 240


Pro Gly 



<210>  9677
<211>  5988
<212>  DNA
<213>  Homo sapiens

<400>  9677
gaatgaatgg ctctggagca cctatgaatt tgaacaataa tctgaatcct atgtttcttg     60

gtccgttgaa tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc    120

ccatcaaccc tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa    180

atgatgtcag agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc    240

atgtaggtcg aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg    300

aagctttgaa acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca    360

cagaaagaca gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt    420

ctggacaaac tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga    480

aaagatcaag gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac    540

catttgaagc agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag    600

atagtattta tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt    660

tcagaaatga ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc    720

gctttattca agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc    780

gaaaaagact gcagaacttc agctatgacc agagggaaat gatactaaat ccagaggggg    840

atgtcaactc tgccaaatta ccctagaaga tatgagagag attgagaaaa atccccctgc    900

ccaaggaaaa aagggattaa agatgcctgt gccaggtaat cctgcagttc caggaatgcc    960

caatgcggga ctgcccggtg tgggactgcc cagtgcagga cttcccggtg caggcctgcc   1020

cagcacagga ctgcctggtt cagcaataac cagtgcagga ctgcctggtg cgggaatgcc   1080

cagtgcagga atacctagtg caggaggtga agagcatgcc ttcctgactg taggatcaaa   1140

ggaagccaat aatgggcctc catttaactt tcctggtaat tttggtggat caaatgcctt   1200

tgggccacca atccctcctc caggattagg aggcggggcc tttggtgatg ctaggcctgg   1260

tatgccttca gttggaaaca gtggtttgcc tggtctagga ctggatgttc cgggttttgg   1320

aggtggacca aacaatttaa gtgggccatc gggatttgga gggggccctc agaattttgg   1380

aaatggccct ggtagcttag gcggtccccc ggggtttgga agtggccctc ctggtcttgg   1440

aagtgcccct gggcatttgg gtgggccacc agcttttggg cctggccccg gccccggccc   1500

cggccctggc ccaatccata ttggtggtcc ccctggcttt gcatctagtt ctggaaaacc   1560

aggaccgaca gtaattaaag tgcaaaacat gccctttact gtgtctattg atgagatttt   1620

agatttcttt tatggctatc aagtaatccc aggctcagtg tgtttaaaat acaatgaaaa   1680

aggtatgccc acaggtgaag ccatggtggc ctttgagtct cgggatgaag ccacagctgc   1740

tgtcattgac ttaaatgaca ggcctatagg ttcaagaaaa gtaaaacttg tattagggta   1800

gccattcaca tcatttttta tagggtagat cttcatattg ctgtgattaa tgcatccaga   1860

ttgttttcct agtatttcca ggttagaacc tgtggattgt ttcaattgca tatagcttgg   1920

tttccataac atagagcatt ggttgactgt ttacagaaga ctcactcacc aggataaaca   1980

ttgctgtatg ttacagtaaa gctatctgga gagaacacat aaatgatttt ggcataccat   2040

tagagaaacc atttgtaaaa ctcaaatgac cacataaagc ttatcaagga gtctagattg   2100

gttttgtttt ataccatatg ggatgaagaa aatagaaatg tcagtagaac tcattgaggg   2160

tgctcttgcc agctgctgaa aatagaagtt ggctactctc agaatttggt ttaaagctgg   2220

acagatttgc tttgttatag ggtaaagctt tgtctaaagt cctcattttc ttttaaaatt   2280

gaataaaatt tctgtataca gattcattgt atgtaccttt attgcttctt aagggtcctt   2340

gctgtataga cagtcctgct tcagaagttg ctgctttgtt tgtctaattg actcatttgt   2400

aaatgagcag aactgttttg ttggtttttt tccctaaata taaaagtcca cacttcgttt   2460

gtgctataac ctcaaacttt gatttctaat gtcacactta aaactgtgtg gaataagact   2520

tttgccataa aaataaacta tggagtcctt tatctaccag agcctttttg gtttgaccgc   2580

cacgatttag gttagtcagt ttaaaaattg ttcatgttgt ttggatggta tcgaaaacca   2640

gaaaccactt ttaataatgt gtttaagata cttgatttga agtccttttc atatggacta   2700

attgtagtat caatttcctc ctgtcccgat tatgtgaaat tttggccttt aaacaaagag   2760

gggcccattc ataagaaagt gttatatcta ggtttttaaa actgaagttg aaattatctt   2820

tgttagcagt agtagtatag aataaaagat ccgtatgctg gttcgtagat tgatacgtgt   2880

tagtcctgtt atttggaggc tttttggcat agttgttcga tcaggagcct gtttactaaa   2940

agtcttcata cagagtacaa gtgcagccgc cagaggagaa aattgagatt cttgaccctt   3000

tcatactctt ttctttggta ttcaggacac taaggcagga ggaccacatg agttctggtt   3060

ggtaagtgtc cttgtcatga aaacacttgc cttacaaggc tctaattatg atttccctag   3120

tcagtgctct gaagatgtgt cacattatat tataaacaat acggaagggg agataggtga   3180

gatgatatga aaaacaaatt ttctcactgt cataaaaggc tctaattatg gttactttcc   3240

ttgtgatgaa aaacttggcc ttacagggct ctagttatgg ttactttccc tagtcaatgc   3300

tctgaaaatg tgtcacatta taaacaatac agaaggagag atagatgaga gatcatgaaa   3360

accaaatttt atcttttaca tggccccttt gtcttcgttt gaaacatccc caacatttcc   3420

tacaaatcag cgtagttaca aaggggtcag tcttttaaaa taagtatttc ctattaaact   3480

atatatatat acagtgcctt tttggtgttg tgagtcagtg gaacactgaa atacagcggt   3540

tgtgtaattt aagagtggca acagtttcat ttgataagat ttgaaaaggc tttttatcac   3600

tacaatctta gaggattgac agtacaggat ttttgtttaa gagaaggatt gtttagactc   3660

aagaggtgac tatgttgtgg gtcttttgat aattcatgaa tacagatttg ctttgaccga   3720

tcactagata ctgcctcctc aatttcaaaa gcaatataac gtttgtatat gctgtttaat   3780

ttaagttaat gttaagtaat catttctcat tccaaagaca atgcaaaaaa cttcagcact   3840

gcttgagagt tgtatttcag ccacagatat tttctccatt ggaaagctat tttcatttta   3900

gaaaaatggg ttgtttgaag atgaaagtct tttatctttt ttcacaattt attttggtta   3960

tatgttcgta cattcttatt aaatatttca tacactttat tgcaactact ttgttatttc   4020

tacatcttag ataaatgctg aaaaggaaaa cgatttcatt gttcatctaa ttaaataaat   4080

taaaagagcg gtttgtgtag aaattggaga gaactatgtt ttatatgaat cacaacagtg   4140

ctcgttgtgg actgtaatta aatgctttgc cctctggaac ttgatttttg tgtatctgag   4200

atttattaac agtgctaact gctaaggata ctgtttatct tgttctgggc attggagttt   4260

cagtttttaa aaaattcttg aaaatgtatt ctgtgaaact actcatacct ctcttcctgc   4320

gaattttctc ctaagaacta ggtttggggt agaaatgaat tgacattatt ttctcatttg   4380

ctttgtatgg tatgaaggat ttgtaaagct ttgctcaaag ttgtgtgcat ttgtaaacac   4440

tatcatgata ttttcaattt tatgtgtaaa ttttattgtc tgtttttggt gactctgaca   4500

ttaatggaag agaatatttt ccattagatt taattttttt tcctctccct tctgattttt   4560

tttttattgg tgttcatttt tcttttgatt taaaggatta gagaaatcta caaatgtatg   4620

tcataaataa gcaaatttgt aaacttttct gaactttagt gaaacattta gttcacaagc   4680

ataatttgga ggtgtgttct gtgtttacac agtagtttgg atgtacaatt attattagtg   4740

gctttttaaa aaatgaaaca gtgttaagtg aaatgtagtt cctagctttg tactccaagt   4800

tgtcaaagca tcaacaatga aaattcgatt aggaaacttt atttaaaatt tcaggtagta   4860

atattcagtg tagttaaggc cagtcttaac ccactggatg aaaatctagg actgtatgga   4920

agtaagcaaa cattacattt ttaggtggaa atagtcagcc ttgcataaaa acaaggatgc   4980

gtgaaagcct taaattccag ctccctttta ctggagtctg tggttgtgta caggtatggg   5040

ccaagtgtaa aatctcatca attttaagaa cactcgggaa atgagtaaag aaaatgtaaa   5100

attgctgcta gtcaaatctt ttggaaagaa tttctggaag tggtcacttt aaaaattatt   5160

ttccaccctt gcaaaattgc cacatttaaa ttgttttact ggcagttcta tagtagtcca   5220

gactttagaa accaaacaca acaaaatggc ttgttgccaa tatggccaca acattgccag   5280

caaatactgc cttggcatca ctcagcagag gtttttgttt ataaagatga agtcttgaat   5340

actgttcaat aaacttgtca aaaaataaaa caggctgatg cttttaatgc tttaactgca   5400

caaaagtact ttactgagct ataatattat cttgtcaggg tttttgtttt gttttgtttt   5460

taaacctgaa aatattttgt gcctttggag aggtagattt ggtaatcttg gagaggtaaa   5520

aattgttgct tatccttgcc tgctaatgct gaagtgtcaa gagaagagga tacttggaac   5580

agcagggagg aaacttgatt caagtccata gtatccacct tttcagaatt ttatgtgtat   5640

gatgtgttgg caaacaaagc ccttaaatgt tgaaaacttt ttatcttgaa agagtttagc   5700

ttgtattaga atttggatac ccagtgtgtt ttagaggggg ctagacatat aattccaggt   5760

agtagctgag ccattattaa ataatcggga tttgactaag caatggacaa atcactgagt   5820

gaaatcagct gcctacagat atccaaaatg gcttttacca tctgaaaggg gtggactgtg   5880

tgataatatg tctccttttc ttgttcagga gagatcagtt atgtaattca ttgttacctg   5940

ctttccagtg ttttacagca agaaatagtt tatcaactat gtgcatca                5988


<210>  9678
<211>  287
<212>  PRT
<213>  Homo sapiens

<400>  9678

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Leu Pro 
        275                 280                 285


<210>  9679
<211>  6159
<212>  DNA
<213>  Homo sapiens

<400>  9679
ttgcctcctg tgcctcctgt gcccccgatt cccccagttc cttctgtgcc acccatgacc     60

ccactgccac ccatgtcggg catgccgccc ttgaatccgc cacctgtggc acctctacct    120

gctggaatga atggctctgg agcacctatg aatttgaaca ataatctgaa tcctatgttt    180

cttggtccgt tgaatcctgt taaccctatc cagatgaact ctcagagcag tgtgaagcca    240

ctccccatca accctgatga tctgtatgtc agtgtgcatg gaatgccctt ttctgcaatg    300

gaaaatgatg tcagagattt ttttcatggg ctccgtgttg atgcagtgca tttgttgaaa    360

gatcatgtag gtcgaaataa tgggaatgga ttggttaagt ttctctcccc tcaagataca    420

tttgaagctt tgaaacgaaa cagaatgctg atgattcaac gctatgtgga agttagccct    480

gccacagaaa gacagtgggt agctgctgga ggccatatca cttttaagca aaatatggga    540

ccttctggac aaactcatcc ccctcctcag acacttccca ggtcaaaatc gcccagtggg    600

cagaaaagat caaggtcaag atcaccacat gaggctggtt tttgtgttta cttgaaaggg    660

ctaccatttg aagcagaaaa caaacatgtc attgattttt ttaaaaagct ggatattgtg    720

gaagatagta tttatatagc ttatggaccc aatgggaaag caactggcga aggctttgta    780

gagttcagaa atgaggctga ctataaggct gctctgtgtc gtcataaaca gtacatgggc    840

aatcgcttta ttcaagttca tccaattact aagaaaggta tgctagaaaa gatagatatg    900

attcgaaaaa gactgcagaa cttcagctat gaccagaggg aaatgatact aaatccagag    960

ggggatgtca actctgccaa agtctgtgcc cacataacaa atattccatt cagcattaca   1020

aagatggatg ttcttcagtt cctagaagga atcccagtgg atgaaaatgc tgtacatgtt   1080

cttgttgata acaatgggca aggtctagga caggcattgg ttcagaatgc ccaatgcggg   1140

actgcccggt gtgggactgc ccagtgcagg acttcccggt gcaggcctgc ccagcacagg   1200

actgcctggt tcagcaataa ccagtgcagg actgcctggt gcgggaatgc ccagtgcagg   1260

aatacctagt gcaggaggtg aagagcatgc cttcctgact gtaggatcaa aggaagccaa   1320

taatgggcct ccatttaact ttcctggtaa ttttggtgga tcaaatgcct ttgggccacc   1380

aatccctcct ccaggattag gaggcggggc ctttggtgat gctaggcctg gtatgccttc   1440

agttggaaac agtggtttgc ctggtctagg actggatgtt ccgggttttg gaggtggacc   1500

aaacaattta agtgggccat cgggatttgg agggggccct cagaattttg gaaatggccc   1560

tggtagctta ggcggtcccc cggggtttgg aagtggccct cctggtcttg gaagtgcccc   1620

tgggcatttg ggtgggccac cagcttttgg gcctggcccc ggccccggcc ccggccctgg   1680

cccaatccat attggtggtc cccctggctt tgcatctagt tctggaaaac caggaccgac   1740

agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt gatgagattt tagatttctt   1800

ttatggctat caagtaatcc caggctcagt gtgtttaaaa tacaatgaaa aaggtatgcc   1860

cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa gccacagctg ctgtcattga   1920

cttaaatgac aggcctatag gttcaagaaa agtaaaactt gtattagggt agccattcac   1980

atcatttttt atagggtaga tcttcatatt gctgtgatta atgcatccag attgttttcc   2040

tagtatttcc aggttagaac ctgtggattg tttcaattgc atatagcttg gtttccataa   2100

catagagcat tggttgactg tttacagaag actcactcac caggataaac attgctgtat   2160

gttacagtaa agctatctgg agagaacaca taaatgattt tggcatacca ttagagaaac   2220

catttgtaaa actcaaatga ccacataaag cttatcaagg agtctagatt ggttttgttt   2280

tataccatat gggatgaaga aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc   2340

cagctgctga aaatagaagt tggctactct cagaatttgg tttaaagctg gacagatttg   2400

ctttgttata gggtaaagct ttgtctaaag tcctcatttt cttttaaaat tgaataaaat   2460

ttctgtatac agattcattg tatgtacctt tattgcttct taagggtcct tgctgtatag   2520

acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt gactcatttg taaatgagca   2580

gaactgtttt gttggttttt ttccctaaat ataaaagtcc acacttcgtt tgtgctataa   2640

cctcaaactt tgatttctaa tgtcacactt aaaactgtgt ggaataagac ttttgccata   2700

aaaataaact atggagtcct ttatctacca gagccttttt ggtttgaccg ccacgattta   2760

ggttagtcag tttaaaaatt gttcatgttg tttggatggt atcgaaaacc agaaaccact   2820

tttaataatg tgtttaagat acttgatttg aagtcctttt catatggact aattgtagta   2880

tcaatttcct cctgtcccga ttatgtgaaa ttttggcctt taaacaaaga ggggcccatt   2940

cataagaaag tgttatatct aggtttttaa aactgaagtt gaaattatct ttgttagcag   3000

tagtagtata gaataaaaga tccgtatgct ggttcgtaga ttgatacgtg ttagtcctgt   3060

tatttggagg ctttttggca tagttgttcg atcaggagcc tgtttactaa aagtcttcat   3120

acagagtaca agtgcagccg ccagaggaga aaattgagat tcttgaccct ttcatactct   3180

tttctttggt attcaggaca ctaaggcagg aggaccacat gagttctggt tggtaagtgt   3240

ccttgtcatg aaaacacttg ccttacaagg ctctaattat gatttcccta gtcagtgctc   3300

tgaagatgtg tcacattata ttataaacaa tacggaaggg gagataggtg agatgatatg   3360

aaaaacaaat tttctcactg tcataaaagg ctctaattat ggttactttc cttgtgatga   3420

aaaacttggc cttacagggc tctagttatg gttactttcc ctagtcaatg ctctgaaaat   3480

gtgtcacatt ataaacaata cagaaggaga gatagatgag agatcatgaa aaccaaattt   3540

tatcttttac atggcccctt tgtcttcgtt tgaaacatcc ccaacatttc ctacaaatca   3600

gcgtagttac aaaggggtca gtcttttaaa ataagtattt cctattaaac tatatatata   3660

tacagtgcct ttttggtgtt gtgagtcagt ggaacactga aatacagcgg ttgtgtaatt   3720

taagagtggc aacagtttca tttgataaga tttgaaaagg ctttttatca ctacaatctt   3780

agaggattga cagtacagga tttttgttta agagaaggat tgtttagact caagaggtga   3840

ctatgttgtg ggtcttttga taattcatga atacagattt gctttgaccg atcactagat   3900

actgcctcct caatttcaaa agcaatataa cgtttgtata tgctgtttaa tttaagttaa   3960

tgttaagtaa tcatttctca ttccaaagac aatgcaaaaa acttcagcac tgcttgagag   4020

ttgtatttca gccacagata ttttctccat tggaaagcta ttttcatttt agaaaaatgg   4080

gttgtttgaa gatgaaagtc ttttatcttt tttcacaatt tattttggtt atatgttcgt   4140

acattcttat taaatatttc atacacttta ttgcaactac tttgttattt ctacatctta   4200

gataaatgct gaaaaggaaa acgatttcat tgttcatcta attaaataaa ttaaaagagc   4260

ggtttgtgta gaaattggag agaactatgt tttatatgaa tcacaacagt gctcgttgtg   4320

gactgtaatt aaatgctttg ccctctggaa cttgattttt gtgtatctga gatttattaa   4380

cagtgctaac tgctaaggat actgtttatc ttgttctggg cattggagtt tcagttttta   4440

aaaaattctt gaaaatgtat tctgtgaaac tactcatacc tctcttcctg cgaattttct   4500

cctaagaact aggtttgggg tagaaatgaa ttgacattat tttctcattt gctttgtatg   4560

gtatgaagga tttgtaaagc tttgctcaaa gttgtgtgca tttgtaaaca ctatcatgat   4620

attttcaatt ttatgtgtaa attttattgt ctgtttttgg tgactctgac attaatggaa   4680

gagaatattt tccattagat ttaatttttt ttcctctccc ttctgatttt ttttttattg   4740

gtgttcattt ttcttttgat ttaaaggatt agagaaatct acaaatgtat gtcataaata   4800

agcaaatttg taaacttttc tgaactttag tgaaacattt agttcacaag cataatttgg   4860

aggtgtgttc tgtgtttaca cagtagtttg gatgtacaat tattattagt ggctttttaa   4920

aaaatgaaac agtgttaagt gaaatgtagt tcctagcttt gtactccaag ttgtcaaagc   4980

atcaacaatg aaaattcgat taggaaactt tatttaaaat ttcaggtagt aatattcagt   5040

gtagttaagg ccagtcttaa cccactggat gaaaatctag gactgtatgg aagtaagcaa   5100

acattacatt tttaggtgga aatagtcagc cttgcataaa aacaaggatg cgtgaaagcc   5160

ttaaattcca gctccctttt actggagtct gtggttgtgt acaggtatgg gccaagtgta   5220

aaatctcatc aattttaaga acactcggga aatgagtaaa gaaaatgtaa aattgctgct   5280

agtcaaatct tttggaaaga atttctggaa gtggtcactt taaaaattat tttccaccct   5340

tgcaaaattg ccacatttaa attgttttac tggcagttct atagtagtcc agactttaga   5400

aaccaaacac aacaaaatgg cttgttgcca atatggccac aacattgcca gcaaatactg   5460

ccttggcatc actcagcaga ggtttttgtt tataaagatg aagtcttgaa tactgttcaa   5520

taaacttgtc aaaaaataaa acaggctgat gcttttaatg ctttaactgc acaaaagtac   5580

tttactgagc tataatatta tcttgtcagg gtttttgttt tgttttgttt ttaaacctga   5640

aaatattttg tgcctttgga gaggtagatt tggtaatctt ggagaggtaa aaattgttgc   5700

ttatccttgc ctgctaatgc tgaagtgtca agagaagagg atacttggaa cagcagggag   5760

gaaacttgat tcaagtccat agtatccacc ttttcagaat tttatgtgta tgatgtgttg   5820

gcaaacaaag cccttaaatg ttgaaaactt tttatcttga aagagtttag cttgtattag   5880

aatttggata cccagtgtgt tttagagggg gctagacata taattccagg tagtagctga   5940

gccattatta aataatcggg atttgactaa gcaatggaca aatcactgag tgaaatcagc   6000

tgcctacaga tatccaaaat ggcttttacc atctgaaagg ggtggactgt gtgataatat   6060

gtctcctttt cttgttcagg agagatcagt tatgtaattc attgttacct gctttccagt   6120

gttttacagc aagaaatagt ttatcaacta tgtgcatca                          6159


<210>  9680
<211>  404
<212>  PRT
<213>  Homo sapiens

<400>  9680

Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro Pro 
1               5                   10                  15


Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro Met 
            20                  25                  30


Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn Pro 
        35                  40                  45


Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro 
    50                  55                  60


Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe Ser 
65                  70                  75                  80


Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val Asp 
                85                  90                  95


Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly 
            100                 105                 110


Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg 
        115                 120                 125


Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr 
    130                 135                 140


Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn 
145                 150                 155                 160


Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg 
                165                 170                 175


Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His 
            180                 185                 190


Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu 
        195                 200                 205


Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp 
    210                 215                 220


Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly 
225                 230                 235                 240


Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg 
                245                 250                 255


His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr 
            260                 265                 270


Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu Gln 
        275                 280                 285


Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly Asp 
    290                 295                 300


Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe Ser 
305                 310                 315                 320


Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val Asp 
                325                 330                 335


Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu Gly 
            340                 345                 350


Gln Ala Leu Val Gln Asn Ala Gln Cys Gly Thr Ala Arg Cys Gly Thr 
        355                 360                 365


Ala Gln Cys Arg Thr Ser Arg Cys Arg Pro Ala Gln His Arg Thr Ala 
    370                 375                 380


Trp Phe Ser Asn Asn Gln Cys Arg Thr Ala Trp Cys Gly Asn Ala Gln 
385                 390                 395                 400


Cys Arg Asn Thr 



<210>  9681
<211>  6915
<212>  DNA
<213>  Homo sapiens

<400>  9681
caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc cgtttgcaag gtctcccaat     60

tgtggcgggg accatggaca ttcgccactt cttctctgga ttgaccattc ctgatggggg    120

cgtgcatatt gtagggggtg aactgggtga ggctttcatc gtttttgcca ctgatgaaga    180

tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa gggtcaaaag taacactatt    240

gttgagtagt aagacggaaa tgcagaatat gattgaactg agtcgtaggc gttttgaaac    300

tgccaactta gatataccac cagcaaatgc cagtagatca ggaccaccac ctagctcagg    360

aatgagtagc agggtaaact tgcccacaac agtatccaac tttaataatc catcacccag    420

tgtagttact gccaccactt ctgttcatga aagcaacaaa aacatacaga cattttccac    480

agccagcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc caacgtttag    540

ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac caattcctcc    600

aattccagcg atgccatctt ctgtgccacc catgacccca ctgccaccca tgtcgggcat    660

gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg gctctggagc    720

acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga atcctgttaa    780

ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc ctgatgatct    840

gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca gagatttttt    900

tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc gaaataatgg    960

gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga aacgaaacag   1020

aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac agtgggtagc   1080

tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa ctcatccccc   1140

tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc   1200

accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag cagaaaacaa   1260

acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt atatagctta   1320

tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg aggctgacta   1380

taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc aagttcatcc   1440

aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac tgcagaactt   1500

cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact ctgccaaagt   1560

ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc ttcagttcct   1620

agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca atgggcaagg   1680

tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt   1740

acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc tagaagatat   1800

gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc   1860

aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg gactgcccag   1920

tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag caataaccag   1980

tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag gaggtgaaga   2040

gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat ttaactttcc   2100

tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag gattaggagg   2160

cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg   2220

tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg ggccatcggg   2280

atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg gtcccccggg   2340

gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg ggccaccagc   2400

ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg gtggtccccc   2460

tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc aaaacatgcc   2520

ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag taatcccagg   2580

ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt   2640

tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc ctataggttc   2700

aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag ggtagatctt   2760

catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt tagaacctgt   2820

ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt tgactgttta   2880

cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct atctggagag   2940

aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc aaatgaccac   3000

ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga tgaagaaaat   3060

agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat agaagttggc   3120

tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt aaagctttgt   3180

ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat tcattgtatg   3240

tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca gaagttgctg   3300

ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg gtttttttcc   3360

ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat ttctaatgtc   3420

acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg agtcctttat   3480

ctaccagagc ctttttggtt tgaccgccac gatttaggtt agtcagttta aaaattgttc   3540

atgttgtttg gatggtatcg aaaaccagaa accactttta ataatgtgtt taagatactt   3600

gatttgaagt ccttttcata tggactaatt gtagtatcaa tttcctcctg tcccgattat   3660

gtgaaatttt ggcctttaaa caaagagggg cccattcata agaaagtgtt atatctaggt   3720

ttttaaaact gaagttgaaa ttatctttgt tagcagtagt agtatagaat aaaagatccg   3780

tatgctggtt cgtagattga tacgtgttag tcctgttatt tggaggcttt ttggcatagt   3840

tgttcgatca ggagcctgtt tactaaaagt cttcatacag agtacaagtg cagccgccag   3900

aggagaaaat tgagattctt gaccctttca tactcttttc tttggtattc aggacactaa   3960

ggcaggagga ccacatgagt tctggttggt aagtgtcctt gtcatgaaaa cacttgcctt   4020

acaaggctct aattatgatt tccctagtca gtgctctgaa gatgtgtcac attatattat   4080

aaacaatacg gaaggggaga taggtgagat gatatgaaaa acaaattttc tcactgtcat   4140

aaaaggctct aattatggtt actttccttg tgatgaaaaa cttggcctta cagggctcta   4200

gttatggtta ctttccctag tcaatgctct gaaaatgtgt cacattataa acaatacaga   4260

aggagagata gatgagagat catgaaaacc aaattttatc ttttacatgg cccctttgtc   4320

ttcgtttgaa acatccccaa catttcctac aaatcagcgt agttacaaag gggtcagtct   4380

tttaaaataa gtatttccta ttaaactata tatatataca gtgccttttt ggtgttgtga   4440

gtcagtggaa cactgaaata cagcggttgt gtaatttaag agtggcaaca gtttcatttg   4500

ataagatttg aaaaggcttt ttatcactac aatcttagag gattgacagt acaggatttt   4560

tgtttaagag aaggattgtt tagactcaag aggtgactat gttgtgggtc ttttgataat   4620

tcatgaatac agatttgctt tgaccgatca ctagatactg cctcctcaat ttcaaaagca   4680

atataacgtt tgtatatgct gtttaattta agttaatgtt aagtaatcat ttctcattcc   4740

aaagacaatg caaaaaactt cagcactgct tgagagttgt atttcagcca cagatatttt   4800

ctccattgga aagctatttt cattttagaa aaatgggttg tttgaagatg aaagtctttt   4860

atcttttttc acaatttatt ttggttatat gttcgtacat tcttattaaa tatttcatac   4920

actttattgc aactactttg ttatttctac atcttagata aatgctgaaa aggaaaacga   4980

tttcattgtt catctaatta aataaattaa aagagcggtt tgtgtagaaa ttggagagaa   5040

ctatgtttta tatgaatcac aacagtgctc gttgtggact gtaattaaat gctttgccct   5100

ctggaacttg atttttgtgt atctgagatt tattaacagt gctaactgct aaggatactg   5160

tttatcttgt tctgggcatt ggagtttcag tttttaaaaa attcttgaaa atgtattctg   5220

tgaaactact catacctctc ttcctgcgaa ttttctccta agaactaggt ttggggtaga   5280

aatgaattga cattattttc tcatttgctt tgtatggtat gaaggatttg taaagctttg   5340

ctcaaagttg tgtgcatttg taaacactat catgatattt tcaattttat gtgtaaattt   5400

tattgtctgt ttttggtgac tctgacatta atggaagaga atattttcca ttagatttaa   5460

ttttttttcc tctcccttct gatttttttt ttattggtgt tcatttttct tttgatttaa   5520

aggattagag aaatctacaa atgtatgtca taaataagca aatttgtaaa cttttctgaa   5580

ctttagtgaa acatttagtt cacaagcata atttggaggt gtgttctgtg tttacacagt   5640

agtttggatg tacaattatt attagtggct ttttaaaaaa tgaaacagtg ttaagtgaaa   5700

tgtagttcct agctttgtac tccaagttgt caaagcatca acaatgaaaa ttcgattagg   5760

aaactttatt taaaatttca ggtagtaata ttcagtgtag ttaaggccag tcttaaccca   5820

ctggatgaaa atctaggact gtatggaagt aagcaaacat tacattttta ggtggaaata   5880

gtcagccttg cataaaaaca aggatgcgtg aaagccttaa attccagctc ccttttactg   5940

gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat ctcatcaatt ttaagaacac   6000

tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc aaatcttttg gaaagaattt   6060

ctggaagtgg tcactttaaa aattattttc cacccttgca aaattgccac atttaaattg   6120

ttttactggc agttctatag tagtccagac tttagaaacc aaacacaaca aaatggcttg   6180

ttgccaatat ggccacaaca ttgccagcaa atactgcctt ggcatcactc agcagaggtt   6240

tttgtttata aagatgaagt cttgaatact gttcaataaa cttgtcaaaa aataaaacag   6300

gctgatgctt ttaatgcttt aactgcacaa aagtacttta ctgagctata atattatctt   6360

gtcagggttt ttgttttgtt ttgtttttaa acctgaaaat attttgtgcc tttggagagg   6420

tagatttggt aatcttggag aggtaaaaat tgttgcttat ccttgcctgc taatgctgaa   6480

gtgtcaagag aagaggatac ttggaacagc agggaggaaa cttgattcaa gtccatagta   6540

tccacctttt cagaatttta tgtgtatgat gtgttggcaa acaaagccct taaatgttga   6600

aaacttttta tcttgaaaga gtttagcttg tattagaatt tggataccca gtgtgtttta   6660

gagggggcta gacatataat tccaggtagt agctgagcca ttattaaata atcgggattt   6720

gactaagcaa tggacaaatc actgagtgaa atcagctgcc tacagatatc caaaatggct   6780

tttaccatct gaaaggggtg gactgtgtga taatatgtct ccttttcttg ttcaggagag   6840

atcagttatg taattcattg ttacctgctt tccagtgttt tacagcaaga aatagtttat   6900

caactatgtg catca                                                    6915


<210>  9682
<211>  900
<212>  PRT
<213>  Homo sapiens

<400>  9682

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
        195                 200                 205


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
    210                 215                 220


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
225                 230                 235                 240


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
                245                 250                 255


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
            260                 265                 270


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
        275                 280                 285


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
    290                 295                 300


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
305                 310                 315                 320


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
                325                 330                 335


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
            340                 345                 350


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
        355                 360                 365


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
    370                 375                 380


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
385                 390                 395                 400


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
                405                 410                 415


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
            420                 425                 430


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
        435                 440                 445


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
    450                 455                 460


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
465                 470                 475                 480


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
                485                 490                 495


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
            500                 505                 510


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
        515                 520                 525


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
    530                 535                 540


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
545                 550                 555                 560


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
                565                 570                 575


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
            580                 585                 590


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
        595                 600                 605


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
    610                 615                 620


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
625                 630                 635                 640


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
                645                 650                 655


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
            660                 665                 670


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
        675                 680                 685


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
    690                 695                 700


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
705                 710                 715                 720


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
                725                 730                 735


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
            740                 745                 750


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
        755                 760                 765


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
    770                 775                 780


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
785                 790                 795                 800


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
                805                 810                 815


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
            820                 825                 830


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
        835                 840                 845


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
    850                 855                 860


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
865                 870                 875                 880


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
                885                 890                 895


Leu Val Leu Gly 
            900


<210>  9683
<211>  7177
<212>  DNA
<213>  Homo sapiens

<400>  9683
gaaatgcctc cgaggtccat tgctggggag gggctttact cgagggtgta gcagttttga     60

gaagccggcg tctgaagcta ggagtctaaa agttggtttt aattggttgc ccacaggatt    120

gacttggcct ctacttcttg ttaaggaaat tcatctcttg ttttatcagg tgtgtgtggt    180

ttcagcgcag catggctgtg gtcatccgtt tgcaaggtct cccaattgtg gcggggacca    240

tggacattcg ccacttcttc tctggattga ccattcctga tgggggcgtg catattgtag    300

ggggtgaact gggtgaggct ttcatcgttt ttgccactga tgaagatgca aggcttggta    360

tgatgcgcac aggtggtaca attaaagggt caaaagtaac actattgttg agtagtaaga    420

cggaaatgca gaatatgatt gaactgagtc gtaggcgttt tgaaactgcc aacttagata    480

taccaccagc aaatgccagt agatcaggac caccacctag ctcaggaatg agtagcaggg    540

taaacttgcc cacaacagta tccaacttta ataatccatc acccagtgta gttactgcca    600

ccacttctgt tcatgaaagc aacaaaaaca tacagacatt ttccacagcc agcgtaggaa    660

cagctcctcc aaatatgggg gcttcctttg ggagcccaac gtttagctca actgttccaa    720

gcacagcctc tccaatgaac acagtcccgc cgccaccaat tcctccaatt ccagcgatgc    780

catctctgcc accaatgcca tccattcccc caattccagt tcctcctcca gtacctacat    840

tgcctcctgt gcctcctgtg cccccgattc ccccagttcc ttctgtgcca cccatgaccc    900

cactgccacc catgtcgggc atgccgccct tgaatccgcc acctgtggca cctctacctg    960

ctggaatgaa tggctctgga gcacctatga atttgaacaa taatctgaat cctatgtttc   1020

ttggtccgtt gaatcctgtt aaccctatcc agatgaactc tcagagcagt gtgaagccac   1080

tccccatcaa ccctgatgat ctgtatgtca gtgtgcatgg aatgcccttt tctgcaatgg   1140

aaaatgatgt cagagatttt tttcatgggc tccgtgttga tgcagtgcat ttgttgaaag   1200

atcatgtagg tcgaaataat gggaatggat tggttaagtt tctctcccct caagatacat   1260

ttgaagcttt gaaacgaaac agaatgctga tgattcaacg ctatgtggaa gttagccctg   1320

ccacagaaag acagtgggta gctgctggag gccatatcac ttttaagcaa aatatgggac   1380

cttctggaca aactcatccc cctcctcaga cacttcccag gtcaaaatcg cccagtgggc   1440

agaaaagatc aaggtcaaga tcaccacatg aggctggttt ttgtgtttac ttgaaagggc   1500

taccatttga agcagaaaac aaacatgtca ttgatttttt taaaaagctg gatattgtgg   1560

aagatagtat ttatatagct tatggaccca atgggaaagc aactggcgaa ggctttgtag   1620

agttcagaaa tgaggctgac tataaggctg ctctgtgtcg tcataaacag tacatgggca   1680

atcgctttat tcaagttcat ccaattacta agaaaggtat gctagaaaag atagatatga   1740

ttcgaaaaag actgcagaac ttcagctatg accagaggga aatgatacta aatccagagg   1800

gggatgtcaa ctctgccaaa gtctgtgccc acataacaaa tattccattc agcattacaa   1860

agatggatgt tcttcagttc ctagaaggaa tcccagtgga tgaaaatgct gtacatgttc   1920

ttgttgataa caatgggcaa ggtctaggac aggcattggt tcagtttaaa aatgaagatg   1980

atgcacgtaa gtctgaacgc ttacaccgta aaaaacttaa tgggagagaa gcttttgttc   2040

atgtagttac cctagaagat atgagagaga ttgagaaaaa tccccctgcc caaggaaaaa   2100

agggattaaa gatgcctgtg ccaggtaatc ctgcagttcc aggaatgccc aatgcgggac   2160

tgcccggtgt gggactgccc agtgcaggac ttcccggtgc aggcctgccc agcacaggac   2220

tgcctggttc agcaataacc agtgcaggac tgcctggtgc gggaatgccc agtgcaggaa   2280

tacctagtgc aggaggtgaa gagcatgcct tcctgactgt aggatcaaag gaagccaata   2340

atgggcctcc atttaacttt cctggtaatt ttggtggatc aaatgccttt gggccaccaa   2400

tccctcctcc aggattagga ggcggggcct ttggtgatgc taggcctggt atgccttcag   2460

ttggaaacag tggtttgcct ggtctaggac tggatgttcc gggttttgga ggtggaccaa   2520

acaatttaag tgggccatcg ggatttggag ggggccctca gaattttgga aatggccctg   2580

gtagcttagg cggtcccccg gggtttggaa gtggccctcc tggtcttgga agtgcccctg   2640

ggcatttggg tgggccacca gcttttgggc ctggccccgg ccccggcccc ggccctggcc   2700

caatccatat tggtggtccc cctggctttg catctagttc tggaaaacca ggaccgacag   2760

taattaaagt gcaaaacatg ccctttactg tgtctattga tgagatttta gatttctttt   2820

atggctatca agtaatccca ggctcagtgt gtttaaaata caatgaaaaa ggtatgccca   2880

caggtgaagc catggtggcc tttgagtctc gggatgaagc cacagctgct gtcattgact   2940

taaatgacag gcctataggt tcaagaaaag taaaacttgt attagggtag ccattcacat   3000

cattttttat agggtagatc ttcatattgc tgtgattaat gcatccagat tgttttccta   3060

gtatttccag gttagaacct gtggattgtt tcaattgcat atagcttggt ttccataaca   3120

tagagcattg gttgactgtt tacagaagac tcactcacca ggataaacat tgctgtatgt   3180

tacagtaaag ctatctggag agaacacata aatgattttg gcataccatt agagaaacca   3240

tttgtaaaac tcaaatgacc acataaagct tatcaaggag tctagattgg ttttgtttta   3300

taccatatgg gatgaagaaa atagaaatgt cagtagaact cattgagggt gctcttgcca   3360

gctgctgaaa atagaagttg gctactctca gaatttggtt taaagctgga cagatttgct   3420

ttgttatagg gtaaagcttt gtctaaagtc ctcattttct tttaaaattg aataaaattt   3480

ctgtatacag attcattgta tgtaccttta ttgcttctta agggtccttg ctgtatagac   3540

agtcctgctt cagaagttgc tgctttgttt gtctaattga ctcatttgta aatgagcaga   3600

actgttttgt tggttttttt ccctaaatat aaaagtccac acttcgtttg tgctataacc   3660

tcaaactttg atttctaatg tcacacttaa aactgtgtgg aataagactt ttgccataaa   3720

aataaactat ggagtccttt atctaccaga gcctttttgg tttgaccgcc acgatttagg   3780

ttagtcagtt taaaaattgt tcatgttgtt tggatggtat cgaaaaccag aaaccacttt   3840

taataatgtg tttaagatac ttgatttgaa gtccttttca tatggactaa ttgtagtatc   3900

aatttcctcc tgtcccgatt atgtgaaatt ttggccttta aacaaagagg ggcccattca   3960

taagaaagtg ttatatctag gtttttaaaa ctgaagttga aattatcttt gttagcagta   4020

gtagtataga ataaaagatc cgtatgctgg ttcgtagatt gatacgtgtt agtcctgtta   4080

tttggaggct ttttggcata gttgttcgat caggagcctg tttactaaaa gtcttcatac   4140

agagtacaag tgcagccgcc agaggagaaa attgagattc ttgacccttt catactcttt   4200

tctttggtat tcaggacact aaggcaggag gaccacatga gttctggttg gtaagtgtcc   4260

ttgtcatgaa aacacttgcc ttacaaggct ctaattatga tttccctagt cagtgctctg   4320

aagatgtgtc acattatatt ataaacaata cggaagggga gataggtgag atgatatgaa   4380

aaacaaattt tctcactgtc ataaaaggct ctaattatgg ttactttcct tgtgatgaaa   4440

aacttggcct tacagggctc tagttatggt tactttccct agtcaatgct ctgaaaatgt   4500

gtcacattat aaacaataca gaaggagaga tagatgagag atcatgaaaa ccaaatttta   4560

tcttttacat ggcccctttg tcttcgtttg aaacatcccc aacatttcct acaaatcagc   4620

gtagttacaa aggggtcagt cttttaaaat aagtatttcc tattaaacta tatatatata   4680

cagtgccttt ttggtgttgt gagtcagtgg aacactgaaa tacagcggtt gtgtaattta   4740

agagtggcaa cagtttcatt tgataagatt tgaaaaggct ttttatcact acaatcttag   4800

aggattgaca gtacaggatt tttgtttaag agaaggattg tttagactca agaggtgact   4860

atgttgtggg tcttttgata attcatgaat acagatttgc tttgaccgat cactagatac   4920

tgcctcctca atttcaaaag caatataacg tttgtatatg ctgtttaatt taagttaatg   4980

ttaagtaatc atttctcatt ccaaagacaa tgcaaaaaac ttcagcactg cttgagagtt   5040

gtatttcagc cacagatatt ttctccattg gaaagctatt ttcattttag aaaaatgggt   5100

tgtttgaaga tgaaagtctt ttatcttttt tcacaattta ttttggttat atgttcgtac   5160

attcttatta aatatttcat acactttatt gcaactactt tgttatttct acatcttaga   5220

taaatgctga aaaggaaaac gatttcattg ttcatctaat taaataaatt aaaagagcgg   5280

tttgtgtaga aattggagag aactatgttt tatatgaatc acaacagtgc tcgttgtgga   5340

ctgtaattaa atgctttgcc ctctggaact tgatttttgt gtatctgaga tttattaaca   5400

gtgctaactg ctaaggatac tgtttatctt gttctgggca ttggagtttc agtttttaaa   5460

aaattcttga aaatgtattc tgtgaaacta ctcatacctc tcttcctgcg aattttctcc   5520

taagaactag gtttggggta gaaatgaatt gacattattt tctcatttgc tttgtatggt   5580

atgaaggatt tgtaaagctt tgctcaaagt tgtgtgcatt tgtaaacact atcatgatat   5640

tttcaatttt atgtgtaaat tttattgtct gtttttggtg actctgacat taatggaaga   5700

gaatattttc cattagattt aatttttttt cctctccctt ctgatttttt ttttattggt   5760

gttcattttt cttttgattt aaaggattag agaaatctac aaatgtatgt cataaataag   5820

caaatttgta aacttttctg aactttagtg aaacatttag ttcacaagca taatttggag   5880

gtgtgttctg tgtttacaca gtagtttgga tgtacaatta ttattagtgg ctttttaaaa   5940

aatgaaacag tgttaagtga aatgtagttc ctagctttgt actccaagtt gtcaaagcat   6000

caacaatgaa aattcgatta ggaaacttta tttaaaattt caggtagtaa tattcagtgt   6060

agttaaggcc agtcttaacc cactggatga aaatctagga ctgtatggaa gtaagcaaac   6120

attacatttt taggtggaaa tagtcagcct tgcataaaaa caaggatgcg tgaaagcctt   6180

aaattccagc tcccttttac tggagtctgt ggttgtgtac aggtatgggc caagtgtaaa   6240

atctcatcaa ttttaagaac actcgggaaa tgagtaaaga aaatgtaaaa ttgctgctag   6300

tcaaatcttt tggaaagaat ttctggaagt ggtcacttta aaaattattt tccacccttg   6360

caaaattgcc acatttaaat tgttttactg gcagttctat agtagtccag actttagaaa   6420

ccaaacacaa caaaatggct tgttgccaat atggccacaa cattgccagc aaatactgcc   6480

ttggcatcac tcagcagagg tttttgttta taaagatgaa gtcttgaata ctgttcaata   6540

aacttgtcaa aaaataaaac aggctgatgc ttttaatgct ttaactgcac aaaagtactt   6600

tactgagcta taatattatc ttgtcagggt ttttgttttg ttttgttttt aaacctgaaa   6660

atattttgtg cctttggaga ggtagatttg gtaatcttgg agaggtaaaa attgttgctt   6720

atccttgcct gctaatgctg aagtgtcaag agaagaggat acttggaaca gcagggagga   6780

aacttgattc aagtccatag tatccacctt ttcagaattt tatgtgtatg atgtgttggc   6840

aaacaaagcc cttaaatgtt gaaaactttt tatcttgaaa gagtttagct tgtattagaa   6900

tttggatacc cagtgtgttt tagagggggc tagacatata attccaggta gtagctgagc   6960

cattattaaa taatcgggat ttgactaagc aatggacaaa tcactgagtg aaatcagctg   7020

cctacagata tccaaaatgg cttttaccat ctgaaagggg tggactgtgt gataatatgt   7080

ctccttttct tgttcaggag agatcagtta tgtaattcat tgttacctgc tttccagtgt   7140

tttacagcaa gaaatagttt atcaactatg tgcatca                            7177


<210>  9684
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9684

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9685
<211>  6661
<212>  DNA
<213>  Homo sapiens

<400>  9685
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc    180

caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac    240

caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt cccccaattc    300

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    360

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    420

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    480

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    540

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    600

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    660

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    720

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    780

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    840

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    900

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    960

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt   1020

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1080

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1140

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1200

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1260

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1320

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1380

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1440

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1500

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1560

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1620

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1680

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1740

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1800

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1860

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1920

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1980

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   2040

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2100

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2160

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2220

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2280

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2340

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2400

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2460

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2520

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2580

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2640

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2700

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2760

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2820

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2880

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2940

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   3000

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3060

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3120

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3180

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3240

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3300

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3360

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3420

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3480

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3540

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3600

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3660

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3720

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3780

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3840

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3900

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3960

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   4020

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4080

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4140

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4200

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4260

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4320

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4380

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4440

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4500

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4560

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4620

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgcaact   4680

actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc attgttcatc   4740

taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat gttttatatg   4800

aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg aacttgattt   4860

ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta tcttgttctg   4920

ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa actactcata   4980

cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg aattgacatt   5040

attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca aagttgtgtg   5100

catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt gtctgttttt   5160

ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt ttttcctctc   5220

ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga ttagagaaat   5280

ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt agtgaaacat   5340

ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt tggatgtaca   5400

attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta gttcctagct   5460

ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac tttatttaaa   5520

atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg atgaaaatct   5580

aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca gccttgcata   5640

aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt ctgtggttgt   5700

gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg gaaatgagta   5760

aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg aagtggtcac   5820

tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt actggcagtt   5880

ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc caatatggcc   5940

acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg tttataaaga   6000

tgaagtcttg aatactgttc aataaacttg tcaaaaaata aaacaggctg atgcttttaa   6060

tgctttaact gcacaaaagt actttactga gctataatat tatcttgtca gggtttttgt   6120

tttgttttgt ttttaaacct gaaaatattt tgtgcctttg gagaggtaga tttggtaatc   6180

ttggagaggt aaaaattgtt gcttatcctt gcctgctaat gctgaagtgt caagagaaga   6240

ggatacttgg aacagcaggg aggaaacttg attcaagtcc atagtatcca ccttttcaga   6300

attttatgtg tatgatgtgt tggcaaacaa agcccttaaa tgttgaaaac tttttatctt   6360

gaaagagttt agcttgtatt agaatttgga tacccagtgt gttttagagg gggctagaca   6420

tataattcca ggtagtagct gagccattat taaataatcg ggatttgact aagcaatgga   6480

caaatcactg agtgaaatca gctgcctaca gatatccaaa atggctttta ccatctgaaa   6540

ggggtggact gtgtgataat atgtctcctt ttcttgttca ggagagatca gttatgtaat   6600

tcattgttac ctgctttcca gtgttttaca gcaagaaata gtttatcaac tatgtgcatc   6660

a                                                                   6661


<210>  9686
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9686

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9687
<211>  7086
<212>  DNA
<213>  Homo sapiens

<400>  9687
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

cattcctgat gggggcgtgc atattgtagg gggtgaactg ggtgaggctt tcatcgtttt    240

tgccactgat gaagatgcaa ggcttggtat gatgcgcaca ggtggtacaa ttaaagggtc    300

aaaagtaaca ctattgttga gtagtaagac ggaaatgcag aatatgattg aactgagtcg    360

taggcgtttt gaaactgcca acttagatat accaccagca aatgccagta gatcaggacc    420

accacctagc tcaggaatga gtagcagggt aaacttgccc acaacagtat ccaactttaa    480

taatccatca cccagtgtag ttactgccac cacttctgtt catgaaagca acaaaaacat    540

acagacattt tccacagcca gcgtaggaac agctcctcca aatatggggg cttcctttgg    600

gagcccaacg tttagctcaa ctgttccaag cacagcctct ccaatgaaca cagtcccgcc    660

gccaccaatt cctccaattc cagcgatgcc atctctgcca ccaatgccat ccattccccc    720

aattccagtt cctcctccag tacctacatt gcctcctgtg cctcctgtgc ccccgattcc    780

cccagttcct tctgtgccac ccatgacccc actgccaccc atgtcgggca tgccgccctt    840

gaatccgcca cctgtggcac ctctacctgc tggaatgaat ggctctggag cacctatgaa    900

tttgaacaat aatctgaatc ctatgtttct tggtccgttg aatcctgtta accctatcca    960

gatgaactct cagagcagtg tgaagccact ccccatcaac cctgatgatc tgtatgtcag   1020

tgtgcatgga atgccctttt ctgcaatgga aaatgatgtc agagattttt ttcatgggct   1080

ccgtgttgat gcagtgcatt tgttgaaaga tcatgtaggt cgaaataatg ggaatggatt   1140

ggttaagttt ctctcccctc aagatacatt tgaagctttg aaacgaaaca gaatgctgat   1200

gattcaacgc tatgtggaag ttagccctgc cacagaaaga cagtgggtag ctgctggagg   1260

ccatatcact tttaagcaaa atatgggacc ttctggacaa actcatcccc ctcctcagac   1320

acttcccagg tcaaaatcgc ccagtgggca gaaaagatca aggtcaagat caccacatga   1380

ggctggtttt tgtgtttact tgaaagggct accatttgaa gcagaaaaca aacatgtcat   1440

tgattttttt aaaaagctgg atattgtgga agatagtatt tatatagctt atggacccaa   1500

tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact ataaggctgc   1560

tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc caattactaa   1620

gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact tcagctatga   1680

ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag tctgtgccca   1740

cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc tagaaggaat   1800

cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag gtctaggaca   1860

ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct tacaccgtaa   1920

aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata tgagagagat   1980

tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc caggtaatcc   2040

tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca gtgcaggact   2100

tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca gtgcaggact   2160

gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag agcatgcctt   2220

cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc ctggtaattt   2280

tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag gcggggcctt   2340

tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg gtctaggact   2400

ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg gatttggagg   2460

gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg ggtttggaag   2520

tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag cttttgggcc   2580

tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc ctggctttgc   2640

atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc cctttactgt   2700

gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag gctcagtgtg   2760

tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct ttgagtctcg   2820

ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt caagaaaagt   2880

aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct tcatattgct   2940

gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg tggattgttt   3000

caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt acagaagact   3060

cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga gaacacataa   3120

atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca cataaagctt   3180

atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa tagaaatgtc   3240

agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg ctactctcag   3300

aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg tctaaagtcc   3360

tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat gtacctttat   3420

tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct gctttgtttg   3480

tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc cctaaatata   3540

aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt cacacttaaa   3600

actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta tctaccagag   3660

cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt catgttgttt   3720

ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact tgatttgaag   3780

tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta tgtgaaattt   3840

tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg tttttaaaac   3900

tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc gtatgctggt   3960

tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag ttgttcgatc   4020

aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca gaggagaaaa   4080

ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta aggcaggagg   4140

accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct tacaaggctc   4200

taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta taaacaatac   4260

ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca taaaaggctc   4320

taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct agttatggtt   4380

actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag aaggagagat   4440

agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt cttcgtttga   4500

aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc ttttaaaata   4560

agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg agtcagtgga   4620

acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt gataagattt   4680

gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt ttgtttaaga   4740

gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa ttcatgaata   4800

cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc aatataacgt   4860

ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc caaagacaat   4920

gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt tctccattgg   4980

aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt tatctttttt   5040

cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata cactttattg   5100

caactacttt gttatttcta catcttagat aaatgctgaa aaggaaaacg atttcattgt   5160

tcatctaatt aaataaatta aaagagcggt ttgtgtagaa attggagaga actatgtttt   5220

atatgaatca caacagtgct cgttgtggac tgtaattaaa tgctttgccc tctggaactt   5280

gatttttgtg tatctgagat ttattaacag tgctaactgc taaggatact gtttatcttg   5340

ttctgggcat tggagtttca gtttttaaaa aattcttgaa aatgtattct gtgaaactac   5400

tcatacctct cttcctgcga attttctcct aagaactagg tttggggtag aaatgaattg   5460

acattatttt ctcatttgct ttgtatggta tgaaggattt gtaaagcttt gctcaaagtt   5520

gtgtgcattt gtaaacacta tcatgatatt ttcaatttta tgtgtaaatt ttattgtctg   5580

tttttggtga ctctgacatt aatggaagag aatattttcc attagattta attttttttc   5640

ctctcccttc tgattttttt tttattggtg ttcatttttc ttttgattta aaggattaga   5700

gaaatctaca aatgtatgtc ataaataagc aaatttgtaa acttttctga actttagtga   5760

aacatttagt tcacaagcat aatttggagg tgtgttctgt gtttacacag tagtttggat   5820

gtacaattat tattagtggc tttttaaaaa atgaaacagt gttaagtgaa atgtagttcc   5880

tagctttgta ctccaagttg tcaaagcatc aacaatgaaa attcgattag gaaactttat   5940

ttaaaatttc aggtagtaat attcagtgta gttaaggcca gtcttaaccc actggatgaa   6000

aatctaggac tgtatggaag taagcaaaca ttacattttt aggtggaaat agtcagcctt   6060

gcataaaaac aaggatgcgt gaaagcctta aattccagct cccttttact ggagtctgtg   6120

gttgtgtaca ggtatgggcc aagtgtaaaa tctcatcaat tttaagaaca ctcgggaaat   6180

gagtaaagaa aatgtaaaat tgctgctagt caaatctttt ggaaagaatt tctggaagtg   6240

gtcactttaa aaattatttt ccacccttgc aaaattgcca catttaaatt gttttactgg   6300

cagttctata gtagtccaga ctttagaaac caaacacaac aaaatggctt gttgccaata   6360

tggccacaac attgccagca aatactgcct tggcatcact cagcagaggt ttttgtttat   6420

aaagatgaag tcttgaatac tgttcaataa acttgtcaaa aaataaaaca ggctgatgct   6480

tttaatgctt taactgcaca aaagtacttt actgagctat aatattatct tgtcagggtt   6540

tttgttttgt tttgttttta aacctgaaaa tattttgtgc ctttggagag gtagatttgg   6600

taatcttgga gaggtaaaaa ttgttgctta tccttgcctg ctaatgctga agtgtcaaga   6660

gaagaggata cttggaacag cagggaggaa acttgattca agtccatagt atccaccttt   6720

tcagaatttt atgtgtatga tgtgttggca aacaaagccc ttaaatgttg aaaacttttt   6780

atcttgaaag agtttagctt gtattagaat ttggataccc agtgtgtttt agagggggct   6840

agacatataa ttccaggtag tagctgagcc attattaaat aatcgggatt tgactaagca   6900

atggacaaat cactgagtga aatcagctgc ctacagatat ccaaaatggc ttttaccatc   6960

tgaaaggggt ggactgtgtg ataatatgtc tccttttctt gttcaggaga gatcagttat   7020

gtaattcatt gttacctgct ttccagtgtt ttacagcaag aaatagttta tcaactatgt   7080

gcatca                                                              7086


<210>  9688
<211>  876
<212>  PRT
<213>  Homo sapiens

<400>  9688

Met Met Arg Thr Gly Gly Thr Ile Lys Gly Ser Lys Val Thr Leu Leu 
1               5                   10                  15


Leu Ser Ser Lys Thr Glu Met Gln Asn Met Ile Glu Leu Ser Arg Arg 
            20                  25                  30


Arg Phe Glu Thr Ala Asn Leu Asp Ile Pro Pro Ala Asn Ala Ser Arg 
        35                  40                  45


Ser Gly Pro Pro Pro Ser Ser Gly Met Ser Ser Arg Val Asn Leu Pro 
    50                  55                  60


Thr Thr Val Ser Asn Phe Asn Asn Pro Ser Pro Ser Val Val Thr Ala 
65                  70                  75                  80


Thr Thr Ser Val His Glu Ser Asn Lys Asn Ile Gln Thr Phe Ser Thr 
                85                  90                  95


Ala Ser Val Gly Thr Ala Pro Pro Asn Met Gly Ala Ser Phe Gly Ser 
            100                 105                 110


Pro Thr Phe Ser Ser Thr Val Pro Ser Thr Ala Ser Pro Met Asn Thr 
        115                 120                 125


Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro Ser Leu Pro 
    130                 135                 140


Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr 
145                 150                 155                 160


Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val 
                165                 170                 175


Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn 
            180                 185                 190


Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala 
        195                 200                 205


Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu 
    210                 215                 220


Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro 
225                 230                 235                 240


Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro 
                245                 250                 255


Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg 
            260                 265                 270


Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly 
        275                 280                 285


Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu 
    290                 295                 300


Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro 
305                 310                 315                 320


Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys 
                325                 330                 335


Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu 
            340                 345                 350


Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser 
        355                 360                 365


Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu 
    370                 375                 380


Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val 
385                 390                 395                 400


Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly 
                405                 410                 415


Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu 
            420                 425                 430


Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro 
        435                 440                 445


Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg 
    450                 455                 460


Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu 
465                 470                 475                 480


Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro 
                485                 490                 495


Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro 
            500                 505                 510


Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly 
        515                 520                 525


Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys 
    530                 535                 540


Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val 
545                 550                 555                 560


His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro 
                565                 570                 575


Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala 
            580                 585                 590


Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser 
        595                 600                 605


Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser 
    610                 615                 620


Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly 
625                 630                 635                 640


Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser 
                645                 650                 655


Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly 
            660                 665                 670


Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly 
        675                 680                 685


Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser 
    690                 695                 700


Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro 
705                 710                 715                 720


Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe 
                725                 730                 735


Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly 
            740                 745                 750


Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala 
        755                 760                 765


Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile 
    770                 775                 780


Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr 
785                 790                 795                 800


Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile 
                805                 810                 815


Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu 
            820                 825                 830


Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe 
        835                 840                 845


Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg 
    850                 855                 860


Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
865                 870                 875


<210>  9689
<211>  6770
<212>  DNA
<213>  Homo sapiens

<400>  9689
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg gtttcagcgc    240

accagcgtag gaacagctcc tccaaatatg ggggcttcct ttgggagccc aacgtttagc    300

tcaactgttc caagcacagc ctctccaatg aacacagtcc cgccgccacc aattcctcca    360

attccagcga tgccatctct gccaccaatg ccatccattc ccccaattcc agttcctcct    420

ccagtaccta cattgcctcc tgtgcctcct gtgcccccga ttcccccagt tccttctgtg    480

ccacccatga ccccactgcc acccatgtcg ggcatgccgc ccttgaatcc gccacctgtg    540

gcacctctac ctgctggaat gaatggctct ggagcaccta tgaatttgaa caataatctg    600

aatcctatgt ttcttggtcc gttgaatcct gttaacccta tccagatgaa ctctcagagc    660

agtgtgaagc cactccccat caaccctgat gatctgtatg tcagtgtgca tggaatgccc    720

ttttctgcaa tggaaaatga tgtcagagat ttttttcatg ggctccgtgt tgatgcagtg    780

catttgttga aagatcatgt aggtcgaaat aatgggaatg gattggttaa gtttctctcc    840

cctcaagata catttgaagc tttgaaacga aacagaatgc tgatgattca acgctatgtg    900

gaagttagcc ctgccacaga aagacagtgg gtagctgctg gaggccatat cacttttaag    960

caaaatatgg gaccttctgg acaaactcat ccccctcctc agacacttcc caggtcaaaa   1020

tcgcccagtg ggcagaaaag atcaaggtca agatcaccac atgaggctgg tttttgtgtt   1080

tacttgaaag ggctaccatt tgaagcagaa aacaaacatg tcattgattt ttttaaaaag   1140

ctggatattg tggaagatag tatttatata gcttatggac ccaatgggaa agcaactggc   1200

gaaggctttg tagagttcag aaatgaggct gactataagg ctgctctgtg tcgtcataaa   1260

cagtacatgg gcaatcgctt tattcaagtt catccaatta ctaagaaagg tatgctagaa   1320

aagatagata tgattcgaaa aagactgcag aacttcagct atgaccagag ggaaatgata   1380

ctaaatccag agggggatgt caactctgcc aaagtctgtg cccacataac aaatattcca   1440

ttcagcatta caaagatgga tgttcttcag ttcctagaag gaatcccagt ggatgaaaat   1500

gctgtacatg ttcttgttga taacaatggg caaggtctag gacaggcatt ggttcagttt   1560

aaaaatgaag atgatgcacg taagtctgaa cgcttacacc gtaaaaaact taatgggaga   1620

gaagcttttg ttcatgtagt taccctagaa gatatgagag agattgagaa aaatccccct   1680

gcccaaggaa aaaagggatt aaagatgcct gtgccaggta atcctgcagt tccaggaatg   1740

cccaatgcgg gactgcccgg tgtgggactg cccagtgcag gacttcccgg tgcaggcctg   1800

cccagcacag gactgcctgg ttcagcaata accagtgcag gactgcctgg tgcgggaatg   1860

cccagtgcag gaatacctag tgcaggaggt gaagagcatg ccttcctgac tgtaggatca   1920

aaggaagcca ataatgggcc tccatttaac tttcctggta attttggtgg atcaaatgcc   1980

tttgggccac caatccctcc tccaggatta ggaggcgggg cctttggtga tgctaggcct   2040

ggtatgcctt cagttggaaa cagtggtttg cctggtctag gactggatgt tccgggtttt   2100

ggaggtggac caaacaattt aagtgggcca tcgggatttg gagggggccc tcagaatttt   2160

ggaaatggcc ctggtagctt aggcggtccc ccggggtttg gaagtggccc tcctggtctt   2220

ggaagtgccc ctgggcattt gggtgggcca ccagcttttg ggcctggccc cggccccggc   2280

cccggccctg gcccaatcca tattggtggt ccccctggct ttgcatctag ttctggaaaa   2340

ccaggaccga cagtaattaa agtgcaaaac atgcccttta ctgtgtctat tgatgagatt   2400

ttagatttct tttatggcta tcaagtaatc ccaggctcag tgtgtttaaa atacaatgaa   2460

aaaggtatgc ccacaggtga agccatggtg gcctttgagt ctcgggatga agccacagct   2520

gctgtcattg acttaaatga caggcctata ggttcaagaa aagtaaaact tgtattaggg   2580

tagccattca catcattttt tatagggtag atcttcatat tgctgtgatt aatgcatcca   2640

gattgttttc ctagtatttc caggttagaa cctgtggatt gtttcaattg catatagctt   2700

ggtttccata acatagagca ttggttgact gtttacagaa gactcactca ccaggataaa   2760

cattgctgta tgttacagta aagctatctg gagagaacac ataaatgatt ttggcatacc   2820

attagagaaa ccatttgtaa aactcaaatg accacataaa gcttatcaag gagtctagat   2880

tggttttgtt ttataccata tgggatgaag aaaatagaaa tgtcagtaga actcattgag   2940

ggtgctcttg ccagctgctg aaaatagaag ttggctactc tcagaatttg gtttaaagct   3000

ggacagattt gctttgttat agggtaaagc tttgtctaaa gtcctcattt tcttttaaaa   3060

ttgaataaaa tttctgtata cagattcatt gtatgtacct ttattgcttc ttaagggtcc   3120

ttgctgtata gacagtcctg cttcagaagt tgctgctttg tttgtctaat tgactcattt   3180

gtaaatgagc agaactgttt tgttggtttt tttccctaaa tataaaagtc cacacttcgt   3240

ttgtgctata acctcaaact ttgatttcta atgtcacact taaaactgtg tggaataaga   3300

cttttgccat aaaaataaac tatggagtcc tttatctacc agagcctttt tggtttgacc   3360

gccacgattt aggttagtca gtttaaaaat tgttcatgtt gtttggatgg tatcgaaaac   3420

cagaaaccac ttttaataat gtgtttaaga tacttgattt gaagtccttt tcatatggac   3480

taattgtagt atcaatttcc tcctgtcccg attatgtgaa attttggcct ttaaacaaag   3540

aggggcccat tcataagaaa gtgttatatc taggttttta aaactgaagt tgaaattatc   3600

tttgttagca gtagtagtat agaataaaag atccgtatgc tggttcgtag attgatacgt   3660

gttagtcctg ttatttggag gctttttggc atagttgttc gatcaggagc ctgtttacta   3720

aaagtcttca tacagagtac aagtgcagcc gccagaggag aaaattgaga ttcttgaccc   3780

tttcatactc ttttctttgg tattcaggac actaaggcag gaggaccaca tgagttctgg   3840

ttggtaagtg tccttgtcat gaaaacactt gccttacaag gctctaatta tgatttccct   3900

agtcagtgct ctgaagatgt gtcacattat attataaaca atacggaagg ggagataggt   3960

gagatgatat gaaaaacaaa ttttctcact gtcataaaag gctctaatta tggttacttt   4020

ccttgtgatg aaaaacttgg ccttacaggg ctctagttat ggttactttc cctagtcaat   4080

gctctgaaaa tgtgtcacat tataaacaat acagaaggag agatagatga gagatcatga   4140

aaaccaaatt ttatctttta catggcccct ttgtcttcgt ttgaaacatc cccaacattt   4200

cctacaaatc agcgtagtta caaaggggtc agtcttttaa aataagtatt tcctattaaa   4260

ctatatatat atacagtgcc tttttggtgt tgtgagtcag tggaacactg aaatacagcg   4320

gttgtgtaat ttaagagtgg caacagtttc atttgataag atttgaaaag gctttttatc   4380

actacaatct tagaggattg acagtacagg atttttgttt aagagaagga ttgtttagac   4440

tcaagaggtg actatgttgt gggtcttttg ataattcatg aatacagatt tgctttgacc   4500

gatcactaga tactgcctcc tcaatttcaa aagcaatata acgtttgtat atgctgttta   4560

atttaagtta atgttaagta atcatttctc attccaaaga caatgcaaaa aacttcagca   4620

ctgcttgaga gttgtatttc agccacagat attttctcca ttggaaagct attttcattt   4680

tagaaaaatg ggttgtttga agatgaaagt cttttatctt ttttcacaat ttattttggt   4740

tatatgttcg tacattctta ttaaatattt catacacttt attgcaacta ctttgttatt   4800

tctacatctt agataaatgc tgaaaaggaa aacgatttca ttgttcatct aattaaataa   4860

attaaaagag cggtttgtgt agaaattgga gagaactatg ttttatatga atcacaacag   4920

tgctcgttgt ggactgtaat taaatgcttt gccctctgga acttgatttt tgtgtatctg   4980

agatttatta acagtgctaa ctgctaagga tactgtttat cttgttctgg gcattggagt   5040

ttcagttttt aaaaaattct tgaaaatgta ttctgtgaaa ctactcatac ctctcttcct   5100

gcgaattttc tcctaagaac taggtttggg gtagaaatga attgacatta ttttctcatt   5160

tgctttgtat ggtatgaagg atttgtaaag ctttgctcaa agttgtgtgc atttgtaaac   5220

actatcatga tattttcaat tttatgtgta aattttattg tctgtttttg gtgactctga   5280

cattaatgga agagaatatt ttccattaga tttaattttt tttcctctcc cttctgattt   5340

tttttttatt ggtgttcatt tttcttttga tttaaaggat tagagaaatc tacaaatgta   5400

tgtcataaat aagcaaattt gtaaactttt ctgaacttta gtgaaacatt tagttcacaa   5460

gcataatttg gaggtgtgtt ctgtgtttac acagtagttt ggatgtacaa ttattattag   5520

tggcttttta aaaaatgaaa cagtgttaag tgaaatgtag ttcctagctt tgtactccaa   5580

gttgtcaaag catcaacaat gaaaattcga ttaggaaact ttatttaaaa tttcaggtag   5640

taatattcag tgtagttaag gccagtctta acccactgga tgaaaatcta ggactgtatg   5700

gaagtaagca aacattacat ttttaggtgg aaatagtcag ccttgcataa aaacaaggat   5760

gcgtgaaagc cttaaattcc agctcccttt tactggagtc tgtggttgtg tacaggtatg   5820

ggccaagtgt aaaatctcat caattttaag aacactcggg aaatgagtaa agaaaatgta   5880

aaattgctgc tagtcaaatc ttttggaaag aatttctgga agtggtcact ttaaaaatta   5940

ttttccaccc ttgcaaaatt gccacattta aattgtttta ctggcagttc tatagtagtc   6000

cagactttag aaaccaaaca caacaaaatg gcttgttgcc aatatggcca caacattgcc   6060

agcaaatact gccttggcat cactcagcag aggtttttgt ttataaagat gaagtcttga   6120

atactgttca ataaacttgt caaaaaataa aacaggctga tgcttttaat gctttaactg   6180

cacaaaagta ctttactgag ctataatatt atcttgtcag ggtttttgtt ttgttttgtt   6240

tttaaacctg aaaatatttt gtgcctttgg agaggtagat ttggtaatct tggagaggta   6300

aaaattgttg cttatccttg cctgctaatg ctgaagtgtc aagagaagag gatacttgga   6360

acagcaggga ggaaacttga ttcaagtcca tagtatccac cttttcagaa ttttatgtgt   6420

atgatgtgtt ggcaaacaaa gcccttaaat gttgaaaact ttttatcttg aaagagttta   6480

gcttgtatta gaatttggat acccagtgtg ttttagaggg ggctagacat ataattccag   6540

gtagtagctg agccattatt aaataatcgg gatttgacta agcaatggac aaatcactga   6600

gtgaaatcag ctgcctacag atatccaaaa tggcttttac catctgaaag gggtggactg   6660

tgtgataata tgtctccttt tcttgttcag gagagatcag ttatgtaatt cattgttacc   6720

tgctttccag tgttttacag caagaaatag tttatcaact atgtgcatca              6770


<210>  9690
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9690

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9691
<211>  6601
<212>  DNA
<213>  Homo sapiens

<400>  9691
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatcttc tgccaccaat gccatccatt cccccaattc    240

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    300

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    360

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    420

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    480

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    540

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    600

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    660

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    720

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    780

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    840

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    900

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt    960

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1020

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1080

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1140

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1200

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1260

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1320

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1380

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1440

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1500

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1560

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1620

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1680

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1740

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1800

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1860

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1920

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   1980

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2040

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2100

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2160

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2220

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2280

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2340

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2400

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2460

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2520

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2580

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2640

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2700

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2760

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2820

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2880

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   2940

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3000

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3060

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3120

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3180

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3240

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3300

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3360

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3420

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3480

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3540

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3600

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3660

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3720

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3780

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3840

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3900

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   3960

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4020

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4080

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4140

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4200

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4260

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4320

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4380

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4440

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4500

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4560

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgcaact   4620

actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc attgttcatc   4680

taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat gttttatatg   4740

aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg aacttgattt   4800

ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta tcttgttctg   4860

ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa actactcata   4920

cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg aattgacatt   4980

attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca aagttgtgtg   5040

catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt gtctgttttt   5100

ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt ttttcctctc   5160

ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga ttagagaaat   5220

ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt agtgaaacat   5280

ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt tggatgtaca   5340

attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta gttcctagct   5400

ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac tttatttaaa   5460

atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg atgaaaatct   5520

aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca gccttgcata   5580

aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt ctgtggttgt   5640

gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg gaaatgagta   5700

aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg aagtggtcac   5760

tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt actggcagtt   5820

ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc caatatggcc   5880

acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg tttataaaga   5940

tgaagtcttg aatactgttc aataaacttg tcaaaaaata aaacaggctg atgcttttaa   6000

tgctttaact gcacaaaagt actttactga gctataatat tatcttgtca gggtttttgt   6060

tttgttttgt ttttaaacct gaaaatattt tgtgcctttg gagaggtaga tttggtaatc   6120

ttggagaggt aaaaattgtt gcttatcctt gcctgctaat gctgaagtgt caagagaaga   6180

ggatacttgg aacagcaggg aggaaacttg attcaagtcc atagtatcca ccttttcaga   6240

attttatgtg tatgatgtgt tggcaaacaa agcccttaaa tgttgaaaac tttttatctt   6300

gaaagagttt agcttgtatt agaatttgga tacccagtgt gttttagagg gggctagaca   6360

tataattcca ggtagtagct gagccattat taaataatcg ggatttgact aagcaatgga   6420

caaatcactg agtgaaatca gctgcctaca gatatccaaa atggctttta ccatctgaaa   6480

ggggtggact gtgtgataat atgtctcctt ttcttgttca ggagagatca gttatgtaat   6540

tcattgttac ctgctttcca gtgttttaca gcaagaaata gtttatcaac tatgtgcatc   6600

a                                                                   6601


<210>  9692
<211>  731
<212>  PRT
<213>  Homo sapiens

<400>  9692

Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr Leu 
1               5                   10                  15


Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val Pro 
            20                  25                  30


Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro 
        35                  40                  45


Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro 
    50                  55                  60


Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn 
65                  70                  75                  80


Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu 
                85                  90                  95


Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe 
            100                 105                 110


Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val 
        115                 120                 125


Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn 
    130                 135                 140


Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys 
145                 150                 155                 160


Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala 
                165                 170                 175


Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln 
            180                 185                 190


Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro 
        195                 200                 205


Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro 
    210                 215                 220


His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala 
225                 230                 235                 240


Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu 
                245                 250                 255


Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu 
            260                 265                 270


Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys 
        275                 280                 285


Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile 
    290                 295                 300


Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu 
305                 310                 315                 320


Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly 
                325                 330                 335


Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe 
            340                 345                 350


Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val 
        355                 360                 365


Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu 
    370                 375                 380


Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys Ser 
385                 390                 395                 400


Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val His 
                405                 410                 415


Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro Ala 
            420                 425                 430


Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala Val 
        435                 440                 445


Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser Ala 
    450                 455                 460


Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser Ala 
465                 470                 475                 480


Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly Ile 
                485                 490                 495


Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser Lys 
            500                 505                 510


Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly Gly 
        515                 520                 525


Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly Gly 
    530                 535                 540


Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser Gly 
545                 550                 555                 560


Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro Asn 
                565                 570                 575


Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe Gly 
            580                 585                 590


Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly Pro 
        595                 600                 605


Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala Phe 
    610                 615                 620


Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile Gly 
625                 630                 635                 640


Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr Val 
                645                 650                 655


Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile Leu 
            660                 665                 670


Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu Lys 
        675                 680                 685


Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe Glu 
    690                 695                 700


Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg Pro 
705                 710                 715                 720


Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
                725                 730


<210>  9693
<211>  6695
<212>  DNA
<213>  Homo sapiens

<400>  9693
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg tgttccaagc    240

acagcctctc caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca    300

tctctgccac caatgccatc cattccccca attccagttc ctcctccagt acctacattg    360

cctcctgtgc ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca    420

ctgccaccca tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct    480

ggaatgaatg gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt    540

ggtccgttga atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc    600

cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa    660

aatgatgtca gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat    720

catgtaggtc gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt    780

gaagctttga aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc    840

acagaaagac agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct    900

tctggacaaa ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag    960

aaaagatcaa ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta   1020

ccatttgaag cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa   1080

gatagtattt atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag   1140

ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat   1200

cgctttattc aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt   1260

cgaaaaagac tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg   1320

gatgtcaact ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag   1380

atggatgttc ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt   1440

gttgataaca atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat   1500

gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat   1560

gtagttaccc tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag   1620

ggattaaaga tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg   1680

cccggtgtgg gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg   1740

cctggttcag caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata   1800

cctagtgcag gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat   1860

gggcctccat ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc   1920

cctcctccag gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt   1980

ggaaacagtg gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac   2040

aatttaagtg ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt   2100

agcttaggcg gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg   2160

catttgggtg ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca   2220

atccatattg gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta   2280

attaaagtgc aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat   2340

ggctatcaag taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca   2400

ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta   2460

aatgacaggc ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca   2520

ttttttatag ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt   2580

atttccaggt tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata   2640

gagcattggt tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta   2700

cagtaaagct atctggagag aacacataaa tgattttggc ataccattag agaaaccatt   2760

tgtaaaactc aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata   2820

ccatatggga tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc   2880

tgctgaaaat agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt   2940

gttatagggt aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct   3000

gtatacagat tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag   3060

tcctgcttca gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac   3120

tgttttgttg gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc   3180

aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa   3240

taaactatgg agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt   3300

agtcagttta aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta   3360

ataatgtgtt taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa   3420

tttcctcctg tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata   3480

agaaagtgtt atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt   3540

agtatagaat aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt   3600

tggaggcttt ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag   3660

agtacaagtg cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc   3720

tttggtattc aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt   3780

gtcatgaaaa cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa   3840

gatgtgtcac attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa   3900

acaaattttc tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa   3960

cttggcctta cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt   4020

cacattataa acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc   4080

ttttacatgg cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt   4140

agttacaaag gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca   4200

gtgccttttt ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag   4260

agtggcaaca gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag   4320

gattgacagt acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat   4380

gttgtgggtc ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg   4440

cctcctcaat ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt   4500

aagtaatcat ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt   4560

atttcagcca cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg   4620

tttgaagatg aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat   4680

tcttattaaa tatttcatac actttattgc aactactttg ttatttctac atcttagata   4740

aatgctgaaa aggaaaacga tttcattgtt catctaatta aataaattaa aagagcggtt   4800

tgtgtagaaa ttggagagaa ctatgtttta tatgaatcac aacagtgctc gttgtggact   4860

gtaattaaat gctttgccct ctggaacttg atttttgtgt atctgagatt tattaacagt   4920

gctaactgct aaggatactg tttatcttgt tctgggcatt ggagtttcag tttttaaaaa   4980

attcttgaaa atgtattctg tgaaactact catacctctc ttcctgcgaa ttttctccta   5040

agaactaggt ttggggtaga aatgaattga cattattttc tcatttgctt tgtatggtat   5100

gaaggatttg taaagctttg ctcaaagttg tgtgcatttg taaacactat catgatattt   5160

tcaattttat gtgtaaattt tattgtctgt ttttggtgac tctgacatta atggaagaga   5220

atattttcca ttagatttaa ttttttttcc tctcccttct gatttttttt ttattggtgt   5280

tcatttttct tttgatttaa aggattagag aaatctacaa atgtatgtca taaataagca   5340

aatttgtaaa cttttctgaa ctttagtgaa acatttagtt cacaagcata atttggaggt   5400

gtgttctgtg tttacacagt agtttggatg tacaattatt attagtggct ttttaaaaaa   5460

tgaaacagtg ttaagtgaaa tgtagttcct agctttgtac tccaagttgt caaagcatca   5520

acaatgaaaa ttcgattagg aaactttatt taaaatttca ggtagtaata ttcagtgtag   5580

ttaaggccag tcttaaccca ctggatgaaa atctaggact gtatggaagt aagcaaacat   5640

tacattttta ggtggaaata gtcagccttg cataaaaaca aggatgcgtg aaagccttaa   5700

attccagctc ccttttactg gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat   5760

ctcatcaatt ttaagaacac tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc   5820

aaatcttttg gaaagaattt ctggaagtgg tcactttaaa aattattttc cacccttgca   5880

aaattgccac atttaaattg ttttactggc agttctatag tagtccagac tttagaaacc   5940

aaacacaaca aaatggcttg ttgccaatat ggccacaaca ttgccagcaa atactgcctt   6000

ggcatcactc agcagaggtt tttgtttata aagatgaagt cttgaatact gttcaataaa   6060

cttgtcaaaa aataaaacag gctgatgctt ttaatgcttt aactgcacaa aagtacttta   6120

ctgagctata atattatctt gtcagggttt ttgttttgtt ttgtttttaa acctgaaaat   6180

attttgtgcc tttggagagg tagatttggt aatcttggag aggtaaaaat tgttgcttat   6240

ccttgcctgc taatgctgaa gtgtcaagag aagaggatac ttggaacagc agggaggaaa   6300

cttgattcaa gtccatagta tccacctttt cagaatttta tgtgtatgat gtgttggcaa   6360

acaaagccct taaatgttga aaacttttta tcttgaaaga gtttagcttg tattagaatt   6420

tggataccca gtgtgtttta gagggggcta gacatataat tccaggtagt agctgagcca   6480

ttattaaata atcgggattt gactaagcaa tggacaaatc actgagtgaa atcagctgcc   6540

tacagatatc caaaatggct tttaccatct gaaaggggtg gactgtgtga taatatgtct   6600

ccttttcttg ttcaggagag atcagttatg taattcattg ttacctgctt tccagtgttt   6660

tacagcaaga aatagtttat caactatgtg catca                              6695


<210>  9694
<211>  751
<212>  PRT
<213>  Homo sapiens

<400>  9694

Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro 
1               5                   10                  15


Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro 
            20                  25                  30


Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val 
        35                  40                  45


Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro 
    50                  55                  60


Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly 
65                  70                  75                  80


Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu 
                85                  90                  95


Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser 
            100                 105                 110


Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His 
        115                 120                 125


Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His 
    130                 135                 140


Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg 
145                 150                 155                 160


Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe 
                165                 170                 175


Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu 
            180                 185                 190


Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile 
        195                 200                 205


Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro 
    210                 215                 220


Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg 
225                 230                 235                 240


Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu 
                245                 250                 255


Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu 
            260                 265                 270


Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys 
        275                 280                 285


Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys 
    290                 295                 300


Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln 
305                 310                 315                 320


Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile 
                325                 330                 335


Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu 
            340                 345                 350


Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr 
        355                 360                 365


Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu 
    370                 375                 380


Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn 
385                 390                 395                 400


Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp 
                405                 410                 415


Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu 
            420                 425                 430


Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys 
        435                 440                 445


Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly 
    450                 455                 460


Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly 
465                 470                 475                 480


Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu 
                485                 490                 495


Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro 
            500                 505                 510


Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr 
        515                 520                 525


Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly 
    530                 535                 540


Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly 
545                 550                 555                 560


Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val 
                565                 570                 575


Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly 
            580                 585                 590


Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro 
        595                 600                 605


Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe 
    610                 615                 620


Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly 
625                 630                 635                 640


Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
                645                 650                 655


Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro 
            660                 665                 670


Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile 
        675                 680                 685


Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser 
    690                 695                 700


Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met 
705                 710                 715                 720


Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu 
                725                 730                 735


Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
            740                 745                 750


<210>  9695
<211>  7153
<212>  DNA
<213>  Homo sapiens

<400>  9695
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccggtgtg tgtggtttca gcgcagcatg gctgtggtca    180

tccgtttgca aggtctccca attgtggcgg ggaccatgga cattcgccac ttcttctctg    240

gattgaccat tcctgatggg ggcgtgcata ttgtaggggg tgaactgggt gaggctttca    300

tcgtttttgc cactgatgaa gatgcaaggc ttggtatgat gcgcacaggt ggtacaatta    360

aagggtcaaa agtaacacta ttgttgagta gtaagacgga aatgcagaat atgattgaac    420

tgagtcgtag gcgttttgaa actgccaact tagatatacc accagcaaat gccagtagat    480

caggaccacc acctagctca ggaatgagta gcagggtaaa cttgcccaca acagtatcca    540

actttaataa tccatcaccc agtgtagtta ctgccaccac ttctgttcat gaaagcaaca    600

aaaacataca gacattttcc acagccagcg taggaacagc tcctccaaat atgggggctt    660

cctttgggag cccaacgttt agctcaactg ttccaagcac agcctctcca atgaacacag    720

tcccgccgcc accaattcct ccaattccag cgatgccatc tctgccacca atgccatcca    780

ttcccccaat tccagttcct cctccagtac ctacattgcc tcctgtgcct cctgtgcccc    840

cgattccccc agttccttct gtgccaccca tgaccccact gccacccatg tcgggcatgc    900

cgcccttgaa tccgccacct gtggcacctc tacctgctgg aatgaatggc tctggagcac    960

ctatgaattt gaacaataat ctgaatccta tgtttcttgg tccgttgaat cctgttaacc   1020

ctatccagat gaactctcag agcagtgtga agccactccc catcaaccct gatgatctgt   1080

atgtcagtgt gcatggaatg cccttttctg caatggaaaa tgatgtcaga gatttttttc   1140

atgggctccg tgttgatgca gtgcatttgt tgaaagatca tgtaggtcga aataatggga   1200

atggattggt taagtttctc tcccctcaag atacatttga agctttgaaa cgaaacagaa   1260

tgctgatgat tcaacgctat gtggaagtta gccctgccac agaaagacag tgggtagctg   1320

ctggaggcca tatcactttt aagcaaaata tgggaccttc tggacaaact catccccctc   1380

ctcagacact tcccaggtca aaatcgccca gtgggcagaa aagatcaagg tcaagatcac   1440

cacatgaggc tggtttttgt gtttacttga aagggctacc atttgaagca gaaaacaaac   1500

atgtcattga tttttttaaa aagctggata ttgtggaaga tagtatttat atagcttatg   1560

gacccaatgg gaaagcaact ggcgaaggct ttgtagagtt cagaaatgag gctgactata   1620

aggctgctct gtgtcgtcat aaacagtaca tgggcaatcg ctttattcaa gttcatccaa   1680

ttactaagaa aggtatgcta gaaaagatag atatgattcg aaaaagactg cagaacttca   1740

gctatgacca gagggaaatg atactaaatc cagaggggga tgtcaactct gccaaagtct   1800

gtgcccacat aacaaatatt ccattcagca ttacaaagat ggatgttctt cagttcctag   1860

aaggaatccc agtggatgaa aatgctgtac atgttcttgt tgataacaat gggcaaggtc   1920

taggacaggc attggttcag tttaaaaatg aagatgatgc acgtaagtct gaacgcttac   1980

accgtaaaaa acttaatggg agagaagctt ttgttcatgt agttacccta gaagatatga   2040

gagagattga gaaaaatccc cctgcccaag gaaaaaaggg attaaagatg cctgtgccag   2100

gtaatcctgc agttccagga atgcccaatg cgggactgcc cggtgtggga ctgcccagtg   2160

caggacttcc cggtgcaggc ctgcccagca caggactgcc tggttcagca ataaccagtg   2220

caggactgcc tggtgcggga atgcccagtg caggaatacc tagtgcagga ggtgaagagc   2280

atgccttcct gactgtagga tcaaaggaag ccaataatgg gcctccattt aactttcctg   2340

gtaattttgg tggatcaaat gcctttgggc caccaatccc tcctccagga ttaggaggcg   2400

gggcctttgg tgatgctagg cctggtatgc cttcagttgg aaacagtggt ttgcctggtc   2460

taggactgga tgttccgggt tttggaggtg gaccaaacaa tttaagtggg ccatcgggat   2520

ttggaggggg ccctcagaat tttggaaatg gccctggtag cttaggcggt cccccggggt   2580

ttggaagtgg ccctcctggt cttggaagtg cccctgggca tttgggtggg ccaccagctt   2640

ttgggcctgg ccccggcccc ggccccggcc ctggcccaat ccatattggt ggtccccctg   2700

gctttgcatc tagttctgga aaaccaggac cgacagtaat taaagtgcaa aacatgccct   2760

ttactgtgtc tattgatgag attttagatt tcttttatgg ctatcaagta atcccaggct   2820

cagtgtgttt aaaatacaat gaaaaaggta tgcccacagg tgaagccatg gtggcctttg   2880

agtctcggga tgaagccaca gctgctgtca ttgacttaaa tgacaggcct ataggttcaa   2940

gaaaagtaaa acttgtatta gggtagccat tcacatcatt ttttataggg tagatcttca   3000

tattgctgtg attaatgcat ccagattgtt ttcctagtat ttccaggtta gaacctgtgg   3060

attgtttcaa ttgcatatag cttggtttcc ataacataga gcattggttg actgtttaca   3120

gaagactcac tcaccaggat aaacattgct gtatgttaca gtaaagctat ctggagagaa   3180

cacataaatg attttggcat accattagag aaaccatttg taaaactcaa atgaccacat   3240

aaagcttatc aaggagtcta gattggtttt gttttatacc atatgggatg aagaaaatag   3300

aaatgtcagt agaactcatt gagggtgctc ttgccagctg ctgaaaatag aagttggcta   3360

ctctcagaat ttggtttaaa gctggacaga tttgctttgt tatagggtaa agctttgtct   3420

aaagtcctca ttttctttta aaattgaata aaatttctgt atacagattc attgtatgta   3480

cctttattgc ttcttaaggg tccttgctgt atagacagtc ctgcttcaga agttgctgct   3540

ttgtttgtct aattgactca tttgtaaatg agcagaactg ttttgttggt ttttttccct   3600

aaatataaaa gtccacactt cgtttgtgct ataacctcaa actttgattt ctaatgtcac   3660

acttaaaact gtgtggaata agacttttgc cataaaaata aactatggag tcctttatct   3720

accagagcct ttttggtttg accgccacga tttaggttag tcagtttaaa aattgttcat   3780

gttgtttgga tggtatcgaa aaccagaaac cacttttaat aatgtgttta agatacttga   3840

tttgaagtcc ttttcatatg gactaattgt agtatcaatt tcctcctgtc ccgattatgt   3900

gaaattttgg cctttaaaca aagaggggcc cattcataag aaagtgttat atctaggttt   3960

ttaaaactga agttgaaatt atctttgtta gcagtagtag tatagaataa aagatccgta   4020

tgctggttcg tagattgata cgtgttagtc ctgttatttg gaggcttttt ggcatagttg   4080

ttcgatcagg agcctgttta ctaaaagtct tcatacagag tacaagtgca gccgccagag   4140

gagaaaattg agattcttga ccctttcata ctcttttctt tggtattcag gacactaagg   4200

caggaggacc acatgagttc tggttggtaa gtgtccttgt catgaaaaca cttgccttac   4260

aaggctctaa ttatgatttc cctagtcagt gctctgaaga tgtgtcacat tatattataa   4320

acaatacgga aggggagata ggtgagatga tatgaaaaac aaattttctc actgtcataa   4380

aaggctctaa ttatggttac tttccttgtg atgaaaaact tggccttaca gggctctagt   4440

tatggttact ttccctagtc aatgctctga aaatgtgtca cattataaac aatacagaag   4500

gagagataga tgagagatca tgaaaaccaa attttatctt ttacatggcc cctttgtctt   4560

cgtttgaaac atccccaaca tttcctacaa atcagcgtag ttacaaaggg gtcagtcttt   4620

taaaataagt atttcctatt aaactatata tatatacagt gcctttttgg tgttgtgagt   4680

cagtggaaca ctgaaataca gcggttgtgt aatttaagag tggcaacagt ttcatttgat   4740

aagatttgaa aaggcttttt atcactacaa tcttagagga ttgacagtac aggatttttg   4800

tttaagagaa ggattgttta gactcaagag gtgactatgt tgtgggtctt ttgataattc   4860

atgaatacag atttgctttg accgatcact agatactgcc tcctcaattt caaaagcaat   4920

ataacgtttg tatatgctgt ttaatttaag ttaatgttaa gtaatcattt ctcattccaa   4980

agacaatgca aaaaacttca gcactgcttg agagttgtat ttcagccaca gatattttct   5040

ccattggaaa gctattttca ttttagaaaa atgggttgtt tgaagatgaa agtcttttat   5100

cttttttcac aatttatttt ggttatatgt tcgtacattc ttattaaata tttcatacac   5160

tttattgcaa ctactttgtt atttctacat cttagataaa tgctgaaaag gaaaacgatt   5220

tcattgttca tctaattaaa taaattaaaa gagcggtttg tgtagaaatt ggagagaact   5280

atgttttata tgaatcacaa cagtgctcgt tgtggactgt aattaaatgc tttgccctct   5340

ggaacttgat ttttgtgtat ctgagattta ttaacagtgc taactgctaa ggatactgtt   5400

tatcttgttc tgggcattgg agtttcagtt tttaaaaaat tcttgaaaat gtattctgtg   5460

aaactactca tacctctctt cctgcgaatt ttctcctaag aactaggttt ggggtagaaa   5520

tgaattgaca ttattttctc atttgctttg tatggtatga aggatttgta aagctttgct   5580

caaagttgtg tgcatttgta aacactatca tgatattttc aattttatgt gtaaatttta   5640

ttgtctgttt ttggtgactc tgacattaat ggaagagaat attttccatt agatttaatt   5700

ttttttcctc tcccttctga tttttttttt attggtgttc atttttcttt tgatttaaag   5760

gattagagaa atctacaaat gtatgtcata aataagcaaa tttgtaaact tttctgaact   5820

ttagtgaaac atttagttca caagcataat ttggaggtgt gttctgtgtt tacacagtag   5880

tttggatgta caattattat tagtggcttt ttaaaaaatg aaacagtgtt aagtgaaatg   5940

tagttcctag ctttgtactc caagttgtca aagcatcaac aatgaaaatt cgattaggaa   6000

actttattta aaatttcagg tagtaatatt cagtgtagtt aaggccagtc ttaacccact   6060

ggatgaaaat ctaggactgt atggaagtaa gcaaacatta catttttagg tggaaatagt   6120

cagccttgca taaaaacaag gatgcgtgaa agccttaaat tccagctccc ttttactgga   6180

gtctgtggtt gtgtacaggt atgggccaag tgtaaaatct catcaatttt aagaacactc   6240

gggaaatgag taaagaaaat gtaaaattgc tgctagtcaa atcttttgga aagaatttct   6300

ggaagtggtc actttaaaaa ttattttcca cccttgcaaa attgccacat ttaaattgtt   6360

ttactggcag ttctatagta gtccagactt tagaaaccaa acacaacaaa atggcttgtt   6420

gccaatatgg ccacaacatt gccagcaaat actgccttgg catcactcag cagaggtttt   6480

tgtttataaa gatgaagtct tgaatactgt tcaataaact tgtcaaaaaa taaaacaggc   6540

tgatgctttt aatgctttaa ctgcacaaaa gtactttact gagctataat attatcttgt   6600

cagggttttt gttttgtttt gtttttaaac ctgaaaatat tttgtgcctt tggagaggta   6660

gatttggtaa tcttggagag gtaaaaattg ttgcttatcc ttgcctgcta atgctgaagt   6720

gtcaagagaa gaggatactt ggaacagcag ggaggaaact tgattcaagt ccatagtatc   6780

caccttttca gaattttatg tgtatgatgt gttggcaaac aaagccctta aatgttgaaa   6840

actttttatc ttgaaagagt ttagcttgta ttagaatttg gatacccagt gtgttttaga   6900

gggggctaga catataattc caggtagtag ctgagccatt attaaataat cgggatttga   6960

ctaagcaatg gacaaatcac tgagtgaaat cagctgccta cagatatcca aaatggcttt   7020

taccatctga aaggggtgga ctgtgtgata atatgtctcc ttttcttgtt caggagagat   7080

cagttatgta attcattgtt acctgctttc cagtgtttta cagcaagaaa tagtttatca   7140

actatgtgca tca                                                      7153


<210>  9696
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9696

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9697
<211>  6415
<212>  DNA
<213>  Homo sapiens

<400>  9697
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccgtctaa aagttggttt taattggttg cccacaggat    180

tgacttggcc tctacctgct ggaatgaatg gctctggagc acctatgaat ttgaacaata    240

atctgaatcc tatgtttctt ggtccgttga atcctgttaa ccctatccag atgaactctc    300

agagcagtgt gaagccactc cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa    360

tgcccttttc tgcaatggaa aatgatgtca gagatttttt tcatgggctc cgtgttgatg    420

cagtgcattt gttgaaagat catgtaggtc gaaataatgg gaatggattg gttaagtttc    480

tctcccctca agatacattt gaagctttga aacgaaacag aatgctgatg attcaacgct    540

atgtggaagt tagccctgcc acagaaagac agtgggtagc tgctggaggc catatcactt    600

ttaagcaaaa tatgggacct tctggacaaa ctcatccccc tcctcagaca cttcccaggt    660

caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc accacatgag gctggttttt    720

gtgtttactt gaaagggcta ccatttgaag cagaaaacaa acatgtcatt gattttttta    780

aaaagctgga tattgtggaa gatagtattt atatagctta tggacccaat gggaaagcaa    840

ctggcgaagg ctttgtagag ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc    900

ataaacagta catgggcaat cgctttattc aagttcatcc aattactaag aaaggtatgc    960

tagaaaagat agatatgatt cgaaaaagac tgcagaactt cagctatgac cagagggaaa   1020

tgatactaaa tccagagggg gatgtcaact ctgccaaagt ctgtgcccac ataacaaata   1080

ttccattcag cattacaaag atggatgttc ttcagttcct agaaggaatc ccagtggatg   1140

aaaatgctgt acatgttctt gttgataaca atgggcaagg tctaggacag gcattggttc   1200

agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg   1260

ggagagaagc ttttgttcat gtagttaccc tagaagatat gagagagatt gagaaaaatc   1320

cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc aggtaatcct gcagttccag   1380

gaatgcccaa tgcgggactg cccggtgtgg gactgcccag tgcaggactt cccggtgcag   1440

gcctgcccag cacaggactg cctggttcag caataaccag tgcaggactg cctggtgcgg   1500

gaatgcccag tgcaggaata cctagtgcag gaggtgaaga gcatgccttc ctgactgtag   1560

gatcaaagga agccaataat gggcctccat ttaactttcc tggtaatttt ggtggatcaa   1620

atgcctttgg gccaccaatc cctcctccag gattaggagg cggggccttt ggtgatgcta   1680

ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg tctaggactg gatgttccgg   1740

gttttggagg tggaccaaac aatttaagtg ggccatcggg atttggaggg ggccctcaga   1800

attttggaaa tggccctggt agcttaggcg gtcccccggg gtttggaagt ggccctcctg   1860

gtcttggaag tgcccctggg catttgggtg ggccaccagc ttttgggcct ggccccggcc   1920

ccggccccgg ccctggccca atccatattg gtggtccccc tggctttgca tctagttctg   1980

gaaaaccagg accgacagta attaaagtgc aaaacatgcc ctttactgtg tctattgatg   2040

agattttaga tttcttttat ggctatcaag taatcccagg ctcagtgtgt ttaaaataca   2100

atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca   2160

cagctgctgt cattgactta aatgacaggc ctataggttc aagaaaagta aaacttgtat   2220

tagggtagcc attcacatca ttttttatag ggtagatctt catattgctg tgattaatgc   2280

atccagattg ttttcctagt atttccaggt tagaacctgt ggattgtttc aattgcatat   2340

agcttggttt ccataacata gagcattggt tgactgttta cagaagactc actcaccagg   2400

ataaacattg ctgtatgtta cagtaaagct atctggagag aacacataaa tgattttggc   2460

ataccattag agaaaccatt tgtaaaactc aaatgaccac ataaagctta tcaaggagtc   2520

tagattggtt ttgttttata ccatatggga tgaagaaaat agaaatgtca gtagaactca   2580

ttgagggtgc tcttgccagc tgctgaaaat agaagttggc tactctcaga atttggttta   2640

aagctggaca gatttgcttt gttatagggt aaagctttgt ctaaagtcct cattttcttt   2700

taaaattgaa taaaatttct gtatacagat tcattgtatg tacctttatt gcttcttaag   2760

ggtccttgct gtatagacag tcctgcttca gaagttgctg ctttgtttgt ctaattgact   2820

catttgtaaa tgagcagaac tgttttgttg gtttttttcc ctaaatataa aagtccacac   2880

ttcgtttgtg ctataacctc aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa   2940

taagactttt gccataaaaa taaactatgg agtcctttat ctaccagagc ctttttggtt   3000

tgaccgccac gatttaggtt agtcagttta aaaattgttc atgttgtttg gatggtatcg   3060

aaaaccagaa accactttta ataatgtgtt taagatactt gatttgaagt ccttttcata   3120

tggactaatt gtagtatcaa tttcctcctg tcccgattat gtgaaatttt ggcctttaaa   3180

caaagagggg cccattcata agaaagtgtt atatctaggt ttttaaaact gaagttgaaa   3240

ttatctttgt tagcagtagt agtatagaat aaaagatccg tatgctggtt cgtagattga   3300

tacgtgttag tcctgttatt tggaggcttt ttggcatagt tgttcgatca ggagcctgtt   3360

tactaaaagt cttcatacag agtacaagtg cagccgccag aggagaaaat tgagattctt   3420

gaccctttca tactcttttc tttggtattc aggacactaa ggcaggagga ccacatgagt   3480

tctggttggt aagtgtcctt gtcatgaaaa cacttgcctt acaaggctct aattatgatt   3540

tccctagtca gtgctctgaa gatgtgtcac attatattat aaacaatacg gaaggggaga   3600

taggtgagat gatatgaaaa acaaattttc tcactgtcat aaaaggctct aattatggtt   3660

actttccttg tgatgaaaaa cttggcctta cagggctcta gttatggtta ctttccctag   3720

tcaatgctct gaaaatgtgt cacattataa acaatacaga aggagagata gatgagagat   3780

catgaaaacc aaattttatc ttttacatgg cccctttgtc ttcgtttgaa acatccccaa   3840

catttcctac aaatcagcgt agttacaaag gggtcagtct tttaaaataa gtatttccta   3900

ttaaactata tatatataca gtgccttttt ggtgttgtga gtcagtggaa cactgaaata   3960

cagcggttgt gtaatttaag agtggcaaca gtttcatttg ataagatttg aaaaggcttt   4020

ttatcactac aatcttagag gattgacagt acaggatttt tgtttaagag aaggattgtt   4080

tagactcaag aggtgactat gttgtgggtc ttttgataat tcatgaatac agatttgctt   4140

tgaccgatca ctagatactg cctcctcaat ttcaaaagca atataacgtt tgtatatgct   4200

gtttaattta agttaatgtt aagtaatcat ttctcattcc aaagacaatg caaaaaactt   4260

cagcactgct tgagagttgt atttcagcca cagatatttt ctccattgga aagctatttt   4320

cattttagaa aaatgggttg tttgaagatg aaagtctttt atcttttttc acaatttatt   4380

ttggttatat gttcgtacat tcttattaaa tatttcatac actttattgc aactactttg   4440

ttatttctac atcttagata aatgctgaaa aggaaaacga tttcattgtt catctaatta   4500

aataaattaa aagagcggtt tgtgtagaaa ttggagagaa ctatgtttta tatgaatcac   4560

aacagtgctc gttgtggact gtaattaaat gctttgccct ctggaacttg atttttgtgt   4620

atctgagatt tattaacagt gctaactgct aaggatactg tttatcttgt tctgggcatt   4680

ggagtttcag tttttaaaaa attcttgaaa atgtattctg tgaaactact catacctctc   4740

ttcctgcgaa ttttctccta agaactaggt ttggggtaga aatgaattga cattattttc   4800

tcatttgctt tgtatggtat gaaggatttg taaagctttg ctcaaagttg tgtgcatttg   4860

taaacactat catgatattt tcaattttat gtgtaaattt tattgtctgt ttttggtgac   4920

tctgacatta atggaagaga atattttcca ttagatttaa ttttttttcc tctcccttct   4980

gatttttttt ttattggtgt tcatttttct tttgatttaa aggattagag aaatctacaa   5040

atgtatgtca taaataagca aatttgtaaa cttttctgaa ctttagtgaa acatttagtt   5100

cacaagcata atttggaggt gtgttctgtg tttacacagt agtttggatg tacaattatt   5160

attagtggct ttttaaaaaa tgaaacagtg ttaagtgaaa tgtagttcct agctttgtac   5220

tccaagttgt caaagcatca acaatgaaaa ttcgattagg aaactttatt taaaatttca   5280

ggtagtaata ttcagtgtag ttaaggccag tcttaaccca ctggatgaaa atctaggact   5340

gtatggaagt aagcaaacat tacattttta ggtggaaata gtcagccttg cataaaaaca   5400

aggatgcgtg aaagccttaa attccagctc ccttttactg gagtctgtgg ttgtgtacag   5460

gtatgggcca agtgtaaaat ctcatcaatt ttaagaacac tcgggaaatg agtaaagaaa   5520

atgtaaaatt gctgctagtc aaatcttttg gaaagaattt ctggaagtgg tcactttaaa   5580

aattattttc cacccttgca aaattgccac atttaaattg ttttactggc agttctatag   5640

tagtccagac tttagaaacc aaacacaaca aaatggcttg ttgccaatat ggccacaaca   5700

ttgccagcaa atactgcctt ggcatcactc agcagaggtt tttgtttata aagatgaagt   5760

cttgaatact gttcaataaa cttgtcaaaa aataaaacag gctgatgctt ttaatgcttt   5820

aactgcacaa aagtacttta ctgagctata atattatctt gtcagggttt ttgttttgtt   5880

ttgtttttaa acctgaaaat attttgtgcc tttggagagg tagatttggt aatcttggag   5940

aggtaaaaat tgttgcttat ccttgcctgc taatgctgaa gtgtcaagag aagaggatac   6000

ttggaacagc agggaggaaa cttgattcaa gtccatagta tccacctttt cagaatttta   6060

tgtgtatgat gtgttggcaa acaaagccct taaatgttga aaacttttta tcttgaaaga   6120

gtttagcttg tattagaatt tggataccca gtgtgtttta gagggggcta gacatataat   6180

tccaggtagt agctgagcca ttattaaata atcgggattt gactaagcaa tggacaaatc   6240

actgagtgaa atcagctgcc tacagatatc caaaatggct tttaccatct gaaaggggtg   6300

gactgtgtga taatatgtct ccttttcttg ttcaggagag atcagttatg taattcattg   6360

ttacctgctt tccagtgttt tacagcaaga aatagtttat caactatgtg catca        6415


<210>  9698
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  9698

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala 
        275                 280                 285


His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln 
    290                 295                 300


Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val 
305                 310                 315                 320


Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn 
                325                 330                 335


Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn 
            340                 345                 350


Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu 
        355                 360                 365


Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro 
    370                 375                 380


Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro 
385                 390                 395                 400


Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser 
                405                 410                 415


Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala 
            420                 425                 430


Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala 
        435                 440                 445


Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn 
    450                 455                 460


Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro 
465                 470                 475                 480


Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met 
                485                 490                 495


Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro 
            500                 505                 510


Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly 
        515                 520                 525


Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro 
    530                 535                 540


Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His 
545                 550                 555                 560


Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly 
                565                 570                 575


Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser 
            580                 585                 590


Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr 
        595                 600                 605


Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile 
    610                 615                 620


Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly 
625                 630                 635                 640


Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val 
                645                 650                 655


Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val 
            660                 665                 670


Leu Gly 



<210>  9699
<211>  6136
<212>  DNA
<213>  Homo sapiens

<400>  9699
ggaacgcgga gccgctgagc gggccgacgg ccattttgtg aagcggcgaa ggaggtggtg     60

gctgcgttgg gctccgggaa gccgttcggg ctggggctgt cggccgcggg gcggaggcac    120

tcgcgcgggg gtctaaaagt tggttttaat tggttgccca caggattgac ttggcctcta    180

cttcttgtta aggaaattca tctcttgttt tatcaggtgt gtgtggtttc agcgcagcat    240

ggctgtggtc atccgtttgc aaggtctccc aattgtggcg gggaccatgg acattcgcca    300

cttcttctct ggattgacca ttcctgatgg gggcgtgcat attgtagggg gtgaactggg    360

tgaggctttc atcgtttttg ccactgatga agatgcaagg cttggtatga tgcgcacagg    420

tggtacaatt aaagggtcaa aagtaacact attgttgagt agtaagacgg aaatgcagaa    480

tatgattgaa ctgatttttt aaaaagctgg atattgtgga agatagtatt tatatagctt    540

atggacccaa tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact    600

ataaggctgc tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc    660

caattactaa gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact    720

tcagctatga ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag    780

tctgtgccca cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc    840

tagaaggaat cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag    900

gtctaggaca ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct    960

tacaccgtaa aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata   1020

tgagagagat tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc   1080

caggtaatcc tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca   1140

gtgcaggact tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca   1200

gtgcaggact gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag   1260

agcatgcctt cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc   1320

ctggtaattt tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag   1380

gcggggcctt tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg   1440

gtctaggact ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg   1500

gatttggagg gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg   1560

ggtttggaag tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag   1620

cttttgggcc tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc   1680

ctggctttgc atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc   1740

cctttactgt gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag   1800

gctcagtgtg tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct   1860

ttgagtctcg ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt   1920

caagaaaagt aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct   1980

tcatattgct gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg   2040

tggattgttt caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt   2100

acagaagact cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga   2160

gaacacataa atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca   2220

cataaagctt atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa   2280

tagaaatgtc agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg   2340

ctactctcag aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg   2400

tctaaagtcc tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat   2460

gtacctttat tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct   2520

gctttgtttg tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc   2580

cctaaatata aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt   2640

cacacttaaa actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta   2700

tctaccagag cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt   2760

catgttgttt ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact   2820

tgatttgaag tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta   2880

tgtgaaattt tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg   2940

tttttaaaac tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc   3000

gtatgctggt tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag   3060

ttgttcgatc aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca   3120

gaggagaaaa ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta   3180

aggcaggagg accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct   3240

tacaaggctc taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta   3300

taaacaatac ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca   3360

taaaaggctc taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct   3420

agttatggtt actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag   3480

aaggagagat agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt   3540

cttcgtttga aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc   3600

ttttaaaata agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg   3660

agtcagtgga acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt   3720

gataagattt gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt   3780

ttgtttaaga gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa   3840

ttcatgaata cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc   3900

aatataacgt ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc   3960

caaagacaat gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt   4020

tctccattgg aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt   4080

tatctttttt cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata   4140

cactttattg caactacttt gttatttcta catcttagat aaatgctgaa aaggaaaacg   4200

atttcattgt tcatctaatt aaataaatta aaagagcggt ttgtgtagaa attggagaga   4260

actatgtttt atatgaatca caacagtgct cgttgtggac tgtaattaaa tgctttgccc   4320

tctggaactt gatttttgtg tatctgagat ttattaacag tgctaactgc taaggatact   4380

gtttatcttg ttctgggcat tggagtttca gtttttaaaa aattcttgaa aatgtattct   4440

gtgaaactac tcatacctct cttcctgcga attttctcct aagaactagg tttggggtag   4500

aaatgaattg acattatttt ctcatttgct ttgtatggta tgaaggattt gtaaagcttt   4560

gctcaaagtt gtgtgcattt gtaaacacta tcatgatatt ttcaatttta tgtgtaaatt   4620

ttattgtctg tttttggtga ctctgacatt aatggaagag aatattttcc attagattta   4680

attttttttc ctctcccttc tgattttttt tttattggtg ttcatttttc ttttgattta   4740

aaggattaga gaaatctaca aatgtatgtc ataaataagc aaatttgtaa acttttctga   4800

actttagtga aacatttagt tcacaagcat aatttggagg tgtgttctgt gtttacacag   4860

tagtttggat gtacaattat tattagtggc tttttaaaaa atgaaacagt gttaagtgaa   4920

atgtagttcc tagctttgta ctccaagttg tcaaagcatc aacaatgaaa attcgattag   4980

gaaactttat ttaaaatttc aggtagtaat attcagtgta gttaaggcca gtcttaaccc   5040

actggatgaa aatctaggac tgtatggaag taagcaaaca ttacattttt aggtggaaat   5100

agtcagcctt gcataaaaac aaggatgcgt gaaagcctta aattccagct cccttttact   5160

ggagtctgtg gttgtgtaca ggtatgggcc aagtgtaaaa tctcatcaat tttaagaaca   5220

ctcgggaaat gagtaaagaa aatgtaaaat tgctgctagt caaatctttt ggaaagaatt   5280

tctggaagtg gtcactttaa aaattatttt ccacccttgc aaaattgcca catttaaatt   5340

gttttactgg cagttctata gtagtccaga ctttagaaac caaacacaac aaaatggctt   5400

gttgccaata tggccacaac attgccagca aatactgcct tggcatcact cagcagaggt   5460

ttttgtttat aaagatgaag tcttgaatac tgttcaataa acttgtcaaa aaataaaaca   5520

ggctgatgct tttaatgctt taactgcaca aaagtacttt actgagctat aatattatct   5580

tgtcagggtt tttgttttgt tttgttttta aacctgaaaa tattttgtgc ctttggagag   5640

gtagatttgg taatcttgga gaggtaaaaa ttgttgctta tccttgcctg ctaatgctga   5700

agtgtcaaga gaagaggata cttggaacag cagggaggaa acttgattca agtccatagt   5760

atccaccttt tcagaatttt atgtgtatga tgtgttggca aacaaagccc ttaaatgttg   5820

aaaacttttt atcttgaaag agtttagctt gtattagaat ttggataccc agtgtgtttt   5880

agagggggct agacatataa ttccaggtag tagctgagcc attattaaat aatcgggatt   5940

tgactaagca atggacaaat cactgagtga aatcagctgc ctacagatat ccaaaatggc   6000

ttttaccatc tgaaaggggt ggactgtgtg ataatatgtc tccttttctt gttcaggaga   6060

gatcagttat gtaattcatt gttacctgct ttccagtgtt ttacagcaag aaatagttta   6120

tcaactatgt gcatca                                                   6136


<210>  9700
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9700

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ile Phe 
                85


<210>  9701
<211>  7225
<212>  DNA
<213>  Homo sapiens

<400>  9701
tggaacgcgg agccgctgag cgggccgacg gccattttgt gaagcggcga aggaggtggt     60

ggctgcgttg ggctccggga agccgttcgg gctggggctg tcggccgcgg ggcggaggca    120

ctcgcgcggg ggtctaaaag ttggttttaa ttggttgccc acaggattga cttggcctct    180

acttcttgtt aaggaaattc atctcttgtt ttatcaggtg tgtgtggttt cagcgcagca    240

tggctgtggt catccgtttg caaggtctcc caattgtggc ggggaccatg gacattcgcc    300

acttcttctc tggattgacc attcctgatg ggggcgtgca tattgtaggg ggtgaactgg    360

gtgaggcttt catcgttttt gccactgatg aagatgcaag gcttggtatg atgcgcacag    420

gtggtacaat taaagggtca aaagtaacac tattgttgag tagtaagacg gaaatgcaga    480

atatgattga actgagtcgt aggcgttttg aaactgccaa cttagatata ccaccagcaa    540

atgccagtag atcaggacca ccacctagct caggaatgag tagcagggta aacttgccca    600

caacagtatc caactttaat aatccatcac ccagtgtagt tactgccacc acttctgttc    660

atgaaagcaa caaaaacata cagacatttt ccacagccag cgtaggaaca gctcctccaa    720

atatgggggc ttcctttggg agcccaacgt ttagctcaac tgttccaagc acagcctctc    780

caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca tctctgccac    840

caatgccatc cattccccca attccagttc ctcctccagt acctacattg cctcctgtgc    900

ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca ctgccaccca    960

tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg   1020

gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga   1080

atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc   1140

ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca   1200

gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc   1260

gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga   1320

aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac   1380

agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa   1440

ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa   1500

ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag   1560

cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt   1620

atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg   1680

aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc   1740

aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac   1800

tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact   1860

ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc   1920

ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca   1980

atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt   2040

ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc   2100

tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga   2160

tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg   2220

gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag   2280

caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag   2340

gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat   2400

ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag   2460

gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg   2520

gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg   2580

ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg   2640

gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg   2700

ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg   2760

gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc   2820

aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag   2880

taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca   2940

tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc   3000

ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag   3060

ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt   3120

tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt   3180

tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct   3240

atctggagag aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc   3300

aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga   3360

tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat   3420

agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt   3480

aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat   3540

tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca   3600

gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg   3660

gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat   3720

ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg   3780

agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt agtcagttta   3840

aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta ataatgtgtt   3900

taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa tttcctcctg   3960

tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata agaaagtgtt   4020

atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt agtatagaat   4080

aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt tggaggcttt   4140

ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag agtacaagtg   4200

cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc tttggtattc   4260

aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt gtcatgaaaa   4320

cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa gatgtgtcac   4380

attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa acaaattttc   4440

tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa cttggcctta   4500

cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt cacattataa   4560

acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc ttttacatgg   4620

cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt agttacaaag   4680

gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca gtgccttttt   4740

ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag agtggcaaca   4800

gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag gattgacagt   4860

acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat gttgtgggtc   4920

ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg cctcctcaat   4980

ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt aagtaatcat   5040

ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt atttcagcca   5100

cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg tttgaagatg   5160

aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat tcttattaaa   5220

tatttcatac actttattgc aactactttg ttatttctac atcttagata aatgctgaaa   5280

aggaaaacga tttcattgtt catctaatta aataaattaa aagagcggtt tgtgtagaaa   5340

ttggagagaa ctatgtttta tatgaatcac aacagtgctc gttgtggact gtaattaaat   5400

gctttgccct ctggaacttg atttttgtgt atctgagatt tattaacagt gctaactgct   5460

aaggatactg tttatcttgt tctgggcatt ggagtttcag tttttaaaaa attcttgaaa   5520

atgtattctg tgaaactact catacctctc ttcctgcgaa ttttctccta agaactaggt   5580

ttggggtaga aatgaattga cattattttc tcatttgctt tgtatggtat gaaggatttg   5640

taaagctttg ctcaaagttg tgtgcatttg taaacactat catgatattt tcaattttat   5700

gtgtaaattt tattgtctgt ttttggtgac tctgacatta atggaagaga atattttcca   5760

ttagatttaa ttttttttcc tctcccttct gatttttttt ttattggtgt tcatttttct   5820

tttgatttaa aggattagag aaatctacaa atgtatgtca taaataagca aatttgtaaa   5880

cttttctgaa ctttagtgaa acatttagtt cacaagcata atttggaggt gtgttctgtg   5940

tttacacagt agtttggatg tacaattatt attagtggct ttttaaaaaa tgaaacagtg   6000

ttaagtgaaa tgtagttcct agctttgtac tccaagttgt caaagcatca acaatgaaaa   6060

ttcgattagg aaactttatt taaaatttca ggtagtaata ttcagtgtag ttaaggccag   6120

tcttaaccca ctggatgaaa atctaggact gtatggaagt aagcaaacat tacattttta   6180

ggtggaaata gtcagccttg cataaaaaca aggatgcgtg aaagccttaa attccagctc   6240

ccttttactg gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat ctcatcaatt   6300

ttaagaacac tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc aaatcttttg   6360

gaaagaattt ctggaagtgg tcactttaaa aattattttc cacccttgca aaattgccac   6420

atttaaattg ttttactggc agttctatag tagtccagac tttagaaacc aaacacaaca   6480

aaatggcttg ttgccaatat ggccacaaca ttgccagcaa atactgcctt ggcatcactc   6540

agcagaggtt tttgtttata aagatgaagt cttgaatact gttcaataaa cttgtcaaaa   6600

aataaaacag gctgatgctt ttaatgcttt aactgcacaa aagtacttta ctgagctata   6660

atattatctt gtcagggttt ttgttttgtt ttgtttttaa acctgaaaat attttgtgcc   6720

tttggagagg tagatttggt aatcttggag aggtaaaaat tgttgcttat ccttgcctgc   6780

taatgctgaa gtgtcaagag aagaggatac ttggaacagc agggaggaaa cttgattcaa   6840

gtccatagta tccacctttt cagaatttta tgtgtatgat gtgttggcaa acaaagccct   6900

taaatgttga aaacttttta tcttgaaaga gtttagcttg tattagaatt tggataccca   6960

gtgtgtttta gagggggcta gacatataat tccaggtagt agctgagcca ttattaaata   7020

atcgggattt gactaagcaa tggacaaatc actgagtgaa atcagctgcc tacagatatc   7080

caaaatggct tttaccatct gaaaggggtg gactgtgtga taatatgtct ccttttcttg   7140

ttcaggagag atcagttatg taattcattg ttacctgctt tccagtgttt tacagcaaga   7200

aatagtttat caactatgtg catca                                         7225


<210>  9702
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9702

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9703
<211>  7271
<212>  DNA
<213>  Homo sapiens

<400>  9703
cttctggaac gcggagccgc tgagcgggcc gacggccatt ttgtgaagcg gcgaaggagg     60

tggtggctgc gttgggctcc gggaagccgt tcgggctggg gctgtcggcc gcggggcgga    120

ggcactcgcg cggggggtaa ttcggggtct gggttctggt gccgcgcagc tttccccgtc    180

taaaagttgg ttttaattgg ttgcccacag gattgacttg gcctctactt cttgttaagg    240

aaattcatct cttgttttat caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc    300

cgtttgcaag gtctcccaat tgtggcgggg accatggaca ttcgccactt cttctctgga    360

ttgaccattc ctgatggggg cgtgcatatt gtagggggtg aactgggtga ggctttcatc    420

gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa    480

gggtcaaaag taacactatt gttgagtagt aagacggaaa tgcagaatat gattgaactg    540

agtcgtaggc gttttgaaac tgccaactta gatataccac cagcaaatgc cagtagatca    600

ggaccaccac ctagctcagg aatgagtagc agggtaaact tgcccacaac agtatccaac    660

tttaataatc catcacccag tgtagttact gccaccactt ctgttcatga aagcaacaaa    720

aacatacaga cattttccac agccagcgta ggaacagctc ctccaaatat gggggcttcc    780

tttgggagcc caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc    840

ccgccgccac caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt    900

cccccaattc cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg    960

attcccccag ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg   1020

cccttgaatc cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct   1080

atgaatttga acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct   1140

atccagatga actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat   1200

gtcagtgtgc atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat   1260

gggctccgtg ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat   1320

ggattggtta agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg   1380

ctgatgattc aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct   1440

ggaggccata tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct   1500

cagacacttc ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca   1560

catgaggctg gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat   1620

gtcattgatt tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga   1680

cccaatggga aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag   1740

gctgctctgt gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt   1800

actaagaaag gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc   1860

tatgaccaga gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt   1920

gcccacataa caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa   1980

ggaatcccag tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta   2040

ggacaggcat tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac   2100

cgtaaaaaac ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga   2160

gagattgaga aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt   2220

aatcctgcag ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca   2280

ggacttcccg gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca   2340

ggactgcctg gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat   2400

gccttcctga ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt   2460

aattttggtg gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg   2520

gcctttggtg atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta   2580

ggactggatg ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt   2640

ggagggggcc ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt   2700

ggaagtggcc ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt   2760

gggcctggcc ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc   2820

tttgcatcta gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt   2880

actgtgtcta ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca   2940

gtgtgtttaa aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag   3000

tctcgggatg aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga   3060

aaagtaaaac ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata   3120

ttgctgtgat taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat   3180

tgtttcaatt gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga   3240

agactcactc accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca   3300

cataaatgat tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa   3360

agcttatcaa ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa   3420

atgtcagtag aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact   3480

ctcagaattt ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa   3540

agtcctcatt ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc   3600

tttattgctt cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt   3660

gtttgtctaa ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa   3720

atataaaagt ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac   3780

ttaaaactgt gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac   3840

cagagccttt ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt   3900

tgtttggatg gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt   3960

tgaagtcctt ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga   4020

aattttggcc tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt   4080

aaaactgaag ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg   4140

ctggttcgta gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt   4200

cgatcaggag cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga   4260

gaaaattgag attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca   4320

ggaggaccac atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa   4380

ggctctaatt atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac   4440

aatacggaag gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa   4500

ggctctaatt atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta   4560

tggttacttt ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga   4620

gagatagatg agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg   4680

tttgaaacat ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta   4740

aaataagtat ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca   4800

gtggaacact gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa   4860

gatttgaaaa ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt   4920

taagagaagg attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat   4980

gaatacagat ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat   5040

aacgtttgta tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag   5100

acaatgcaaa aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc   5160

attggaaagc tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct   5220

tttttcacaa tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt   5280

tattgcaact actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc   5340

attgttcatc taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat   5400

gttttatatg aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg   5460

aacttgattt ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta   5520

tcttgttctg ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa   5580

actactcata cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg   5640

aattgacatt attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca   5700

aagttgtgtg catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt   5760

gtctgttttt ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt   5820

ttttcctctc ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga   5880

ttagagaaat ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt   5940

agtgaaacat ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt   6000

tggatgtaca attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta   6060

gttcctagct ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac   6120

tttatttaaa atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg   6180

atgaaaatct aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca   6240

gccttgcata aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt   6300

ctgtggttgt gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg   6360

gaaatgagta aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg   6420

aagtggtcac tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt   6480

actggcagtt ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc   6540

caatatggcc acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg   6600

tttataaaga tgaagtcttg aatactgttc aataaacttg tcaaaaaata aaacaggctg   6660

atgcttttaa tgctttaact gcacaaaagt actttactga gctataatat tatcttgtca   6720

gggtttttgt tttgttttgt ttttaaacct gaaaatattt tgtgcctttg gagaggtaga   6780

tttggtaatc ttggagaggt aaaaattgtt gcttatcctt gcctgctaat gctgaagtgt   6840

caagagaaga ggatacttgg aacagcaggg aggaaacttg attcaagtcc atagtatcca   6900

ccttttcaga attttatgtg tatgatgtgt tggcaaacaa agcccttaaa tgttgaaaac   6960

tttttatctt gaaagagttt agcttgtatt agaatttgga tacccagtgt gttttagagg   7020

gggctagaca tataattcca ggtagtagct gagccattat taaataatcg ggatttgact   7080

aagcaatgga caaatcactg agtgaaatca gctgcctaca gatatccaaa atggctttta   7140

ccatctgaaa ggggtggact gtgtgataat atgtctcctt ttcttgttca ggagagatca   7200

gttatgtaat tcattgttac ctgctttcca gtgttttaca gcaagaaata gtttatcaac   7260

tatgtgcatc a                                                        7271


<210>  9704
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9704

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9705
<211>  7139
<212>  DNA
<213>  Homo sapiens

<400>  9705
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggagga ttgacttggc ctctacttct tgttaaggaa attcatctct    120

tgttttatca ggtgtgtgtg gtttcagcgc agcatggctg tggtcatccg tttgcaaggt    180

ctcccaattg tggcggggac catggacatt cgccacttct tctctggatt gaccattcct    240

gatgggggcg tgcatattgt agggggtgaa ctgggtgagg ctttcatcgt ttttgccact    300

gatgaagatg caaggcttgg tatgatgcgc acaggtggta caattaaagg gtcaaaagta    360

acactattgt tgagtagtaa gacggaaatg cagaatatga ttgaactgag tcgtaggcgt    420

tttgaaactg ccaacttaga tataccacca gcaaatgcca gtagatcagg accaccacct    480

agctcaggaa tgagtagcag ggtaaacttg cccacaacag tatccaactt taataatcca    540

tcacccagtg tagttactgc caccacttct gttcatgaaa gcaacaaaaa catacagaca    600

ttttccacag ccagcgtagg aacagctcct ccaaatatgg gggcttcctt tgggagccca    660

acgtttagct caactgttcc aagcacagcc tctccaatga acacagtccc gccgccacca    720

attcctccaa ttccagcgat gccatctctg ccaccaatgc catccattcc cccaattcca    780

gttcctcctc cagtacctac attgcctcct gtgcctcctg tgcccccgat tcccccagtt    840

ccttctgtgc cacccatgac cccactgcca cccatgtcgg gcatgccgcc cttgaatccg    900

ccacctgtgg cacctctacc tgctggaatg aatggctctg gagcacctat gaatttgaac    960

aataatctga atcctatgtt tcttggtccg ttgaatcctg ttaaccctat ccagatgaac   1020

tctcagagca gtgtgaagcc actccccatc aaccctgatg atctgtatgt cagtgtgcat   1080

ggaatgccct tttctgcaat ggaaaatgat gtcagagatt tttttcatgg gctccgtgtt   1140

gatgcagtgc atttgttgaa agatcatgta ggtcgaaata atgggaatgg attggttaag   1200

tttctctccc ctcaagatac atttgaagct ttgaaacgaa acagaatgct gatgattcaa   1260

cgctatgtgg aagttagccc tgccacagaa agacagtggg tagctgctgg aggccatatc   1320

acttttaagc aaaatatggg accttctgga caaactcatc cccctcctca gacacttccc   1380

aggtcaaaat cgcccagtgg gcagaaaaga tcaaggtcaa gatcaccaca tgaggctggt   1440

ttttgtgttt acttgaaagg gctaccattt gaagcagaaa acaaacatgt cattgatttt   1500

tttaaaaagc tggatattgt ggaagatagt atttatatag cttatggacc caatgggaaa   1560

gcaactggcg aaggctttgt agagttcaga aatgaggctg actataaggc tgctctgtgt   1620

cgtcataaac agtacatggg caatcgcttt attcaagttc atccaattac taagaaaggt   1680

atgctagaaa agatagatat gattcgaaaa agactgcaga acttcagcta tgaccagagg   1740

gaaatgatac taaatccaga gggggatgtc aactctgcca aagtctgtgc ccacataaca   1800

aatattccat tcagcattac aaagatggat gttcttcagt tcctagaagg aatcccagtg   1860

gatgaaaatg ctgtacatgt tcttgttgat aacaatgggc aaggtctagg acaggcattg   1920

gttcagttta aaaatgaaga tgatgcacgt aagtctgaac gcttacaccg taaaaaactt   1980

aatgggagag aagcttttgt tcatgtagtt accctagaag atatgagaga gattgagaaa   2040

aatccccctg cccaaggaaa aaagggatta aagatgcctg tgccaggtaa tcctgcagtt   2100

ccaggaatgc ccaatgcggg actgcccggt gtgggactgc ccagtgcagg acttcccggt   2160

gcaggcctgc ccagcacagg actgcctggt tcagcaataa ccagtgcagg actgcctggt   2220

gcgggaatgc ccagtgcagg aatacctagt gcaggaggtg aagagcatgc cttcctgact   2280

gtaggatcaa aggaagccaa taatgggcct ccatttaact ttcctggtaa ttttggtgga   2340

tcaaatgcct ttgggccacc aatccctcct ccaggattag gaggcggggc ctttggtgat   2400

gctaggcctg gtatgccttc agttggaaac agtggtttgc ctggtctagg actggatgtt   2460

ccgggttttg gaggtggacc aaacaattta agtgggccat cgggatttgg agggggccct   2520

cagaattttg gaaatggccc tggtagctta ggcggtcccc cggggtttgg aagtggccct   2580

cctggtcttg gaagtgcccc tgggcatttg ggtgggccac cagcttttgg gcctggcccc   2640

ggccccggcc ccggccctgg cccaatccat attggtggtc cccctggctt tgcatctagt   2700

tctggaaaac caggaccgac agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt   2760

gatgagattt tagatttctt ttatggctat caagtaatcc caggctcagt gtgtttaaaa   2820

tacaatgaaa aaggtatgcc cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa   2880

gccacagctg ctgtcattga cttaaatgac aggcctatag gttcaagaaa agtaaaactt   2940

gtattagggt agccattcac atcatttttt atagggtaga tcttcatatt gctgtgatta   3000

atgcatccag attgttttcc tagtatttcc aggttagaac ctgtggattg tttcaattgc   3060

atatagcttg gtttccataa catagagcat tggttgactg tttacagaag actcactcac   3120

caggataaac attgctgtat gttacagtaa agctatctgg agagaacaca taaatgattt   3180

tggcatacca ttagagaaac catttgtaaa actcaaatga ccacataaag cttatcaagg   3240

agtctagatt ggttttgttt tataccatat gggatgaaga aaatagaaat gtcagtagaa   3300

ctcattgagg gtgctcttgc cagctgctga aaatagaagt tggctactct cagaatttgg   3360

tttaaagctg gacagatttg ctttgttata gggtaaagct ttgtctaaag tcctcatttt   3420

cttttaaaat tgaataaaat ttctgtatac agattcattg tatgtacctt tattgcttct   3480

taagggtcct tgctgtatag acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt   3540

gactcatttg taaatgagca gaactgtttt gttggttttt ttccctaaat ataaaagtcc   3600

acacttcgtt tgtgctataa cctcaaactt tgatttctaa tgtcacactt aaaactgtgt   3660

ggaataagac ttttgccata aaaataaact atggagtcct ttatctacca gagccttttt   3720

ggtttgaccg ccacgattta ggttagtcag tttaaaaatt gttcatgttg tttggatggt   3780

atcgaaaacc agaaaccact tttaataatg tgtttaagat acttgatttg aagtcctttt   3840

catatggact aattgtagta tcaatttcct cctgtcccga ttatgtgaaa ttttggcctt   3900

taaacaaaga ggggcccatt cataagaaag tgttatatct aggtttttaa aactgaagtt   3960

gaaattatct ttgttagcag tagtagtata gaataaaaga tccgtatgct ggttcgtaga   4020

ttgatacgtg ttagtcctgt tatttggagg ctttttggca tagttgttcg atcaggagcc   4080

tgtttactaa aagtcttcat acagagtaca agtgcagccg ccagaggaga aaattgagat   4140

tcttgaccct ttcatactct tttctttggt attcaggaca ctaaggcagg aggaccacat   4200

gagttctggt tggtaagtgt ccttgtcatg aaaacacttg ccttacaagg ctctaattat   4260

gatttcccta gtcagtgctc tgaagatgtg tcacattata ttataaacaa tacggaaggg   4320

gagataggtg agatgatatg aaaaacaaat tttctcactg tcataaaagg ctctaattat   4380

ggttactttc cttgtgatga aaaacttggc cttacagggc tctagttatg gttactttcc   4440

ctagtcaatg ctctgaaaat gtgtcacatt ataaacaata cagaaggaga gatagatgag   4500

agatcatgaa aaccaaattt tatcttttac atggcccctt tgtcttcgtt tgaaacatcc   4560

ccaacatttc ctacaaatca gcgtagttac aaaggggtca gtcttttaaa ataagtattt   4620

cctattaaac tatatatata tacagtgcct ttttggtgtt gtgagtcagt ggaacactga   4680

aatacagcgg ttgtgtaatt taagagtggc aacagtttca tttgataaga tttgaaaagg   4740

ctttttatca ctacaatctt agaggattga cagtacagga tttttgttta agagaaggat   4800

tgtttagact caagaggtga ctatgttgtg ggtcttttga taattcatga atacagattt   4860

gctttgaccg atcactagat actgcctcct caatttcaaa agcaatataa cgtttgtata   4920

tgctgtttaa tttaagttaa tgttaagtaa tcatttctca ttccaaagac aatgcaaaaa   4980

acttcagcac tgcttgagag ttgtatttca gccacagata ttttctccat tggaaagcta   5040

ttttcatttt agaaaaatgg gttgtttgaa gatgaaagtc ttttatcttt tttcacaatt   5100

tattttggtt atatgttcgt acattcttat taaatatttc atacacttta ttgcaactac   5160

tttgttattt ctacatctta gataaatgct gaaaaggaaa acgatttcat tgttcatcta   5220

attaaataaa ttaaaagagc ggtttgtgta gaaattggag agaactatgt tttatatgaa   5280

tcacaacagt gctcgttgtg gactgtaatt aaatgctttg ccctctggaa cttgattttt   5340

gtgtatctga gatttattaa cagtgctaac tgctaaggat actgtttatc ttgttctggg   5400

cattggagtt tcagttttta aaaaattctt gaaaatgtat tctgtgaaac tactcatacc   5460

tctcttcctg cgaattttct cctaagaact aggtttgggg tagaaatgaa ttgacattat   5520

tttctcattt gctttgtatg gtatgaagga tttgtaaagc tttgctcaaa gttgtgtgca   5580

tttgtaaaca ctatcatgat attttcaatt ttatgtgtaa attttattgt ctgtttttgg   5640

tgactctgac attaatggaa gagaatattt tccattagat ttaatttttt ttcctctccc   5700

ttctgatttt ttttttattg gtgttcattt ttcttttgat ttaaaggatt agagaaatct   5760

acaaatgtat gtcataaata agcaaatttg taaacttttc tgaactttag tgaaacattt   5820

agttcacaag cataatttgg aggtgtgttc tgtgtttaca cagtagtttg gatgtacaat   5880

tattattagt ggctttttaa aaaatgaaac agtgttaagt gaaatgtagt tcctagcttt   5940

gtactccaag ttgtcaaagc atcaacaatg aaaattcgat taggaaactt tatttaaaat   6000

ttcaggtagt aatattcagt gtagttaagg ccagtcttaa cccactggat gaaaatctag   6060

gactgtatgg aagtaagcaa acattacatt tttaggtgga aatagtcagc cttgcataaa   6120

aacaaggatg cgtgaaagcc ttaaattcca gctccctttt actggagtct gtggttgtgt   6180

acaggtatgg gccaagtgta aaatctcatc aattttaaga acactcggga aatgagtaaa   6240

gaaaatgtaa aattgctgct agtcaaatct tttggaaaga atttctggaa gtggtcactt   6300

taaaaattat tttccaccct tgcaaaattg ccacatttaa attgttttac tggcagttct   6360

atagtagtcc agactttaga aaccaaacac aacaaaatgg cttgttgcca atatggccac   6420

aacattgcca gcaaatactg ccttggcatc actcagcaga ggtttttgtt tataaagatg   6480

aagtcttgaa tactgttcaa taaacttgtc aaaaaataaa acaggctgat gcttttaatg   6540

ctttaactgc acaaaagtac tttactgagc tataatatta tcttgtcagg gtttttgttt   6600

tgttttgttt ttaaacctga aaatattttg tgcctttgga gaggtagatt tggtaatctt   6660

ggagaggtaa aaattgttgc ttatccttgc ctgctaatgc tgaagtgtca agagaagagg   6720

atacttggaa cagcagggag gaaacttgat tcaagtccat agtatccacc ttttcagaat   6780

tttatgtgta tgatgtgttg gcaaacaaag cccttaaatg ttgaaaactt tttatcttga   6840

aagagtttag cttgtattag aatttggata cccagtgtgt tttagagggg gctagacata   6900

taattccagg tagtagctga gccattatta aataatcggg atttgactaa gcaatggaca   6960

aatcactgag tgaaatcagc tgcctacaga tatccaaaat ggcttttacc atctgaaagg   7020

ggtggactgt gtgataatat gtctcctttt cttgttcagg agagatcagt tatgtaattc   7080

attgttacct gctttccagt gttttacagc aagaaatagt ttatcaacta tgtgcatca    7139


<210>  9706
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9706

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9707
<211>  4130
<212>  DNA
<213>  Homo sapiens

<400>  9707
tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc ccatcaaccc     60

tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa atgatgtcag    120

agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc atgtaggtcg    180

aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg aagctttgaa    240

acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca cagaaagaca    300

gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt ctggacaaac    360

tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga aaagatcaag    420

gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac catttgaagc    480

agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag atagtattta    540

tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt tcagaaatga    600

ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc gctttattca    660

agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc gaaaaagatg    720

tttacagaag actcactcac caggataaac attgctgtat gttacagtaa agctatctgg    780

agagaacaca taaatgattt tggcatacca ttagagaaac catttgtaaa actcaaatga    840

ccacataaag cttatcaagg agtctagatt ggttttgttt tataccatat gggatgaaga    900

aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc cagctgctga aaatagaagt    960

tggctactct cagaatttgg tttaaagctg gacagatttg ctttgttata gggtaaagct   1020

ttgtctaaag tcctcatttt cttttaaaat tgaataaaat ttctgtatac agattcattg   1080

tatgtacctt tattgcttct taagggtcct tgctgtatag acagtcctgc ttcagaagtt   1140

gctgctttgt ttgtctaatt gactcatttg taaatgagca gaactgtttt gttggttttt   1200

ttccctaaat ataaaagtcc acacttcgtt tgtgctataa cctcaaactt tgatttctaa   1260

tgtcacactt aaaactgtgt ggaataagac ttttgccata aaaataaact atggagtcct   1320

ttatctacca gagccttttt ggtttgaccg ccacgattta ggttagtcag tttaaaaatt   1380

gttcatgttg tttggatggt atcgaaaacc agaaaccact tttaataatg tgtttaagat   1440

acttgatttg aagtcctttt catatggact aattgtagta tcaatttcct cctgtcccga   1500

ttatgtgaaa ttttggcctt taaacaaaga ggggcccatt cataagaaag tgttatatct   1560

aggtttttaa aactgaagtt gaaattatct ttgttagcag tagtagtata gaataaaaga   1620

tccgtatgct ggttcgtaga ttgatacgtg ttagtcctgt tatttggagg ctttttggca   1680

tagttgttcg atcaggagcc tgtttactaa aagtcttcat acagagtaca agtgcagccg   1740

ccagaggaga aaattgagat tcttgaccct ttcatactct tttctttggt attcaggaca   1800

ctaaggcagg aggaccacat gagttctggt tggtaagtgt ccttgtcatg aaaacacttg   1860

ccttacaagg ctctaattat gatttcccta gtcagtgctc tgaagatgtg tcacattata   1920

ttataaacaa tacggaaggg gagataggtg agatgatatg aaaaacaaat tttctcactg   1980

tcataaaagg ctctaattat ggttactttc cttgtgatga aaaacttggc cttacagggc   2040

tctagttatg gttactttcc ctagtcaatg ctctgaaaat gtgtcacatt ataaacaata   2100

cagaaggaga gatagatgag agatcatgaa aaccaaattt tatcttttac atggcccctt   2160

tgtcttcgtt tgaaacatcc ccaacatttc ctacaaatca gcgtagttac aaaggggtca   2220

gtcttttaaa ataagtattt cctattaaac tatatatata tacagtgcct ttttggtgtt   2280

gtgagtcagt ggaacactga aatacagcgg ttgtgtaatt taagagtggc aacagtttca   2340

tttgataaga tttgaaaagg ctttttatca ctacaatctt agaggattga cagtacagga   2400

tttttgttta agagaaggat tgtttagact caagaggtga ctatgttgtg ggtcttttga   2460

taattcatga atacagattt gctttgaccg atcactagat actgcctcct caatttcaaa   2520

agcaatataa cgtttgtata tgctgtttaa tttaagttaa tgttaagtaa tcatttctca   2580

ttccaaagac aatgcaaaaa acttcagcac tgcttgagag ttgtatttca gccacagata   2640

ttttctccat tggaaagcta ttttcatttt agaaaaatgg gttgtttgaa gatgaaagtc   2700

ttttatcttt tttcacaatt tattttggtt atatgttcgt acattcttat taaatatttc   2760

atacacttta ttgcaactac tttgttattt ctacatctta gataaatgct gaaaaggaaa   2820

acgatttcat tgttcatcta attaaataaa ttaaaagagc ggtttgtgta gaaattggag   2880

agaactatgt tttatatgaa tcacaacagt gctcgttgtg gactgtaatt aaatgctttg   2940

ccctctggaa cttgattttt gtgtatctga gatttattaa cagtgctaac tgctaaggat   3000

actgtttatc ttgttctggg cattggagtt tcagttttta aaaaattctt gaaaatgtat   3060

tctgtgaaac tactcatacc tctcttcctg cgaattttct cctaagaact aggtttgggg   3120

tagaaatgaa ttgacattat tttctcattt gctttgtatg gtatgaagga tttgtaaagc   3180

tttgctcaaa gttgtgtgca tttgtaaaca ctatcatgat attttcaatt ttatgtgtaa   3240

attttattgt ctgtttttgg tgactctgac attaatggaa gagaatattt tccattagat   3300

ttaatttttt ttcctctccc ttctgatttt ttttttattg gtgttcattt ttcttttgat   3360

ttaaaggatt agagaaatct acaaatgtat gtcataaata agcaaatttg taaacttttc   3420

tgaactttag tgaaacattt agttcacaag cataatttgg aggtgtgttc tgtgtttaca   3480

cagtagtttg gatgtacaat tattattagt ggctttttaa aaaatgaaac agtgttaagt   3540

gaaatgtagt tcctagcttt gtactccaag ttgtcaaagc atcaacaatg aaaattcgat   3600

taggaaactt tatttaaaat ttcaggtagt aatattcagt gtagttaagg ccagtcttaa   3660

cccactggat gaaaatctag gactgtatgg aagtaagcaa acattacatt tttaggtgga   3720

aatagtcagc cttgcataaa aacaaggatg cgtgaaagcc ttaaattcca gctccctttt   3780

actggagtct gtggttgtgt acaggtatgg gccaagtgta aaatctcatc aattttaaga   3840

acactcggga aatgagtaaa gaaaatgtaa aattgctgct agtcaaatct tttggaaaga   3900

atttctggaa gtggtcactt taaaaattat tttccaccct tgcaaaattg ccacatttaa   3960

attgttttac tggcagttct atagtagtcc agactttaga aaccaaacac aacaaaatgg   4020

cttgttgcca atatggccac aacattgcca gcaaatactg ccttggcatc actcagcaga   4080

ggtttttgtt tataaagatg aagtcttgaa tactgttcaa taaacttgtc              4130


<210>  9708
<211>  242
<212>  PRT
<213>  Homo sapiens

<400>  9708

Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp 
1               5                   10                  15


Leu Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp 
            20                  25                  30


Val Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu 
        35                  40                  45


Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu 
    50                  55                  60


Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met 
65                  70                  75                  80


Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val 
                85                  90                  95


Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly 
            100                 105                 110


Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser 
        115                 120                 125


Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys 
    130                 135                 140


Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile 
145                 150                 155                 160


Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala 
                165                 170                 175


Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg 
            180                 185                 190


Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met 
        195                 200                 205


Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu 
    210                 215                 220


Glu Lys Ile Asp Met Ile Arg Lys Arg Cys Leu Gln Lys Thr His Ser 
225                 230                 235                 240


Pro Gly 



<210>  9709
<211>  5359
<212>  DNA
<213>  Homo sapiens

<400>  9709
gaatgaatgg ctctggagca cctatgaatt tgaacaataa tctgaatcct atgtttcttg     60

gtccgttgaa tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc    120

ccatcaaccc tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa    180

atgatgtcag agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc    240

atgtaggtcg aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg    300

aagctttgaa acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca    360

cagaaagaca gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt    420

ctggacaaac tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga    480

aaagatcaag gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac    540

catttgaagc agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag    600

atagtattta tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt    660

tcagaaatga ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc    720

gctttattca agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc    780

gaaaaagact gcagaacttc agctatgacc agagggaaat gatactaaat ccagaggggg    840

atgtcaactc tgccaaatta ccctagaaga tatgagagag attgagaaaa atccccctgc    900

ccaaggaaaa aagggattaa agatgcctgt gccaggtaat cctgcagttc caggaatgcc    960

caatgcggga ctgcccggtg tgggactgcc cagtgcagga cttcccggtg caggcctgcc   1020

cagcacagga ctgcctggtt cagcaataac cagtgcagga ctgcctggtg cgggaatgcc   1080

cagtgcagga atacctagtg caggaggtga agagcatgcc ttcctgactg taggatcaaa   1140

ggaagccaat aatgggcctc catttaactt tcctggtaat tttggtggat caaatgcctt   1200

tgggccacca atccctcctc caggattagg aggcggggcc tttggtgatg ctaggcctgg   1260

tatgccttca gttggaaaca gtggtttgcc tggtctagga ctggatgttc cgggttttgg   1320

aggtggacca aacaatttaa gtgggccatc gggatttgga gggggccctc agaattttgg   1380

aaatggccct ggtagcttag gcggtccccc ggggtttgga agtggccctc ctggtcttgg   1440

aagtgcccct gggcatttgg gtgggccacc agcttttggg cctggccccg gccccggccc   1500

cggccctggc ccaatccata ttggtggtcc ccctggcttt gcatctagtt ctggaaaacc   1560

aggaccgaca gtaattaaag tgcaaaacat gccctttact gtgtctattg atgagatttt   1620

agatttcttt tatggctatc aagtaatccc aggctcagtg tgtttaaaat acaatgaaaa   1680

aggtatgccc acaggtgaag ccatggtggc ctttgagtct cgggatgaag ccacagctgc   1740

tgtcattgac ttaaatgaca ggcctatagg ttcaagaaaa gtaaaacttg tattagggta   1800

gccattcaca tcatttttta tagggtagat cttcatattg ctgtgattaa tgcatccaga   1860

ttgttttcct agtatttcca ggttagaacc tgtggattgt ttcaattgca tatagcttgg   1920

tttccataac atagagcatt ggttgactgt ttacagaaga ctcactcacc aggataaaca   1980

ttgctgtatg ttacagtaaa gctatctgga gagaacacat aaatgatttt ggcataccat   2040

tagagaaacc atttgtaaaa ctcaaatgac cacataaagc ttatcaagga gtctagattg   2100

gttttgtttt ataccatatg ggatgaagaa aatagaaatg tcagtagaac tcattgaggg   2160

tgctcttgcc agctgctgaa aatagaagtt ggctactctc agaatttggt ttaaagctgg   2220

acagatttgc tttgttatag ggtaaagctt tgtctaaagt cctcattttc ttttaaaatt   2280

gaataaaatt tctgtataca gattcattgt atgtaccttt attgcttctt aagggtcctt   2340

gctgtataga cagtcctgct tcagaagttg ctgctttgtt tgtctaattg actcatttgt   2400

aaatgagcag aactgttttg ttggtttttt tccctaaata taaaagtcca cacttcgttt   2460

gtgctataac ctcaaacttt gatttctaat gtcacactta aaactgtgtg gaataagact   2520

tttgccataa aaataaacta tggagtcctt tatctaccag agcctttttg gtttgaccgc   2580

cacgatttag gttagtcagt ttaaaaattg ttcatgttgt ttggatggta tcgaaaacca   2640

gaaaccactt ttaataatgt gtttaagata cttgatttga agtccttttc atatggacta   2700

attgtagtat caatttcctc ctgtcccgat tatgtgaaat tttggccttt aaacaaagag   2760

gggcccattc ataagaaagt gttatatcta ggtttttaaa actgaagttg aaattatctt   2820

tgttagcagt agtagtatag aataaaagat ccgtatgctg gttcgtagat tgatacgtgt   2880

tagtcctgtt atttggaggc tttttggcat agttgttcga tcaggagcct gtttactaaa   2940

agtcttcata cagagtacaa gtgcagccgc cagaggagaa aattgagatt cttgaccctt   3000

tcatactctt ttctttggta ttcaggacac taaggcagga ggaccacatg agttctggtt   3060

ggtaagtgtc cttgtcatga aaacacttgc cttacaaggc tctaattatg atttccctag   3120

tcagtgctct gaagatgtgt cacattatat tataaacaat acggaagggg agataggtga   3180

gatgatatga aaaacaaatt ttctcactgt cataaaaggc tctaattatg gttactttcc   3240

ttgtgatgaa aaacttggcc ttacagggct ctagttatgg ttactttccc tagtcaatgc   3300

tctgaaaatg tgtcacatta taaacaatac agaaggagag atagatgaga gatcatgaaa   3360

accaaatttt atcttttaca tggccccttt gtcttcgttt gaaacatccc caacatttcc   3420

tacaaatcag cgtagttaca aaggggtcag tcttttaaaa taagtatttc ctattaaact   3480

atatatatat acagtgcctt tttggtgttg tgagtcagtg gaacactgaa atacagcggt   3540

tgtgtaattt aagagtggca acagtttcat ttgataagat ttgaaaaggc tttttatcac   3600

tacaatctta gaggattgac agtacaggat ttttgtttaa gagaaggatt gtttagactc   3660

aagaggtgac tatgttgtgg gtcttttgat aattcatgaa tacagatttg ctttgaccga   3720

tcactagata ctgcctcctc aatttcaaaa gcaatataac gtttgtatat gctgtttaat   3780

ttaagttaat gttaagtaat catttctcat tccaaagaca atgcaaaaaa cttcagcact   3840

gcttgagagt tgtatttcag ccacagatat tttctccatt ggaaagctat tttcatttta   3900

gaaaaatggg ttgtttgaag atgaaagtct tttatctttt ttcacaattt attttggtta   3960

tatgttcgta cattcttatt aaatatttca tacactttat tgcaactact ttgttatttc   4020

tacatcttag ataaatgctg aaaaggaaaa cgatttcatt gttcatctaa ttaaataaat   4080

taaaagagcg gtttgtgtag aaattggaga gaactatgtt ttatatgaat cacaacagtg   4140

ctcgttgtgg actgtaatta aatgctttgc cctctggaac ttgatttttg tgtatctgag   4200

atttattaac agtgctaact gctaaggata ctgtttatct tgttctgggc attggagttt   4260

cagtttttaa aaaattcttg aaaatgtatt ctgtgaaact actcatacct ctcttcctgc   4320

gaattttctc ctaagaacta ggtttggggt agaaatgaat tgacattatt ttctcatttg   4380

ctttgtatgg tatgaaggat ttgtaaagct ttgctcaaag ttgtgtgcat ttgtaaacac   4440

tatcatgata ttttcaattt tatgtgtaaa ttttattgtc tgtttttggt gactctgaca   4500

ttaatggaag agaatatttt ccattagatt taattttttt tcctctccct tctgattttt   4560

tttttattgg tgttcatttt tcttttgatt taaaggatta gagaaatcta caaatgtatg   4620

tcataaataa gcaaatttgt aaacttttct gaactttagt gaaacattta gttcacaagc   4680

ataatttgga ggtgtgttct gtgtttacac agtagtttgg atgtacaatt attattagtg   4740

gctttttaaa aaatgaaaca gtgttaagtg aaatgtagtt cctagctttg tactccaagt   4800

tgtcaaagca tcaacaatga aaattcgatt aggaaacttt atttaaaatt tcaggtagta   4860

atattcagtg tagttaaggc cagtcttaac ccactggatg aaaatctagg actgtatgga   4920

agtaagcaaa cattacattt ttaggtggaa atagtcagcc ttgcataaaa acaaggatgc   4980

gtgaaagcct taaattccag ctccctttta ctggagtctg tggttgtgta caggtatggg   5040

ccaagtgtaa aatctcatca attttaagaa cactcgggaa atgagtaaag aaaatgtaaa   5100

attgctgcta gtcaaatctt ttggaaagaa tttctggaag tggtcacttt aaaaattatt   5160

ttccaccctt gcaaaattgc cacatttaaa ttgttttact ggcagttcta tagtagtcca   5220

gactttagaa accaaacaca acaaaatggc ttgttgccaa tatggccaca acattgccag   5280

caaatactgc cttggcatca ctcagcagag gtttttgttt ataaagatga agtcttgaat   5340

actgttcaat aaacttgtc                                                5359


<210>  9710
<211>  287
<212>  PRT
<213>  Homo sapiens

<400>  9710

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Leu Pro 
        275                 280                 285


<210>  9711
<211>  5530
<212>  DNA
<213>  Homo sapiens

<400>  9711
ttgcctcctg tgcctcctgt gcccccgatt cccccagttc cttctgtgcc acccatgacc     60

ccactgccac ccatgtcggg catgccgccc ttgaatccgc cacctgtggc acctctacct    120

gctggaatga atggctctgg agcacctatg aatttgaaca ataatctgaa tcctatgttt    180

cttggtccgt tgaatcctgt taaccctatc cagatgaact ctcagagcag tgtgaagcca    240

ctccccatca accctgatga tctgtatgtc agtgtgcatg gaatgccctt ttctgcaatg    300

gaaaatgatg tcagagattt ttttcatggg ctccgtgttg atgcagtgca tttgttgaaa    360

gatcatgtag gtcgaaataa tgggaatgga ttggttaagt ttctctcccc tcaagataca    420

tttgaagctt tgaaacgaaa cagaatgctg atgattcaac gctatgtgga agttagccct    480

gccacagaaa gacagtgggt agctgctgga ggccatatca cttttaagca aaatatggga    540

ccttctggac aaactcatcc ccctcctcag acacttccca ggtcaaaatc gcccagtggg    600

cagaaaagat caaggtcaag atcaccacat gaggctggtt tttgtgttta cttgaaaggg    660

ctaccatttg aagcagaaaa caaacatgtc attgattttt ttaaaaagct ggatattgtg    720

gaagatagta tttatatagc ttatggaccc aatgggaaag caactggcga aggctttgta    780

gagttcagaa atgaggctga ctataaggct gctctgtgtc gtcataaaca gtacatgggc    840

aatcgcttta ttcaagttca tccaattact aagaaaggta tgctagaaaa gatagatatg    900

attcgaaaaa gactgcagaa cttcagctat gaccagaggg aaatgatact aaatccagag    960

ggggatgtca actctgccaa agtctgtgcc cacataacaa atattccatt cagcattaca   1020

aagatggatg ttcttcagtt cctagaagga atcccagtgg atgaaaatgc tgtacatgtt   1080

cttgttgata acaatgggca aggtctagga caggcattgg ttcagaatgc ccaatgcggg   1140

actgcccggt gtgggactgc ccagtgcagg acttcccggt gcaggcctgc ccagcacagg   1200

actgcctggt tcagcaataa ccagtgcagg actgcctggt gcgggaatgc ccagtgcagg   1260

aatacctagt gcaggaggtg aagagcatgc cttcctgact gtaggatcaa aggaagccaa   1320

taatgggcct ccatttaact ttcctggtaa ttttggtgga tcaaatgcct ttgggccacc   1380

aatccctcct ccaggattag gaggcggggc ctttggtgat gctaggcctg gtatgccttc   1440

agttggaaac agtggtttgc ctggtctagg actggatgtt ccgggttttg gaggtggacc   1500

aaacaattta agtgggccat cgggatttgg agggggccct cagaattttg gaaatggccc   1560

tggtagctta ggcggtcccc cggggtttgg aagtggccct cctggtcttg gaagtgcccc   1620

tgggcatttg ggtgggccac cagcttttgg gcctggcccc ggccccggcc ccggccctgg   1680

cccaatccat attggtggtc cccctggctt tgcatctagt tctggaaaac caggaccgac   1740

agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt gatgagattt tagatttctt   1800

ttatggctat caagtaatcc caggctcagt gtgtttaaaa tacaatgaaa aaggtatgcc   1860

cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa gccacagctg ctgtcattga   1920

cttaaatgac aggcctatag gttcaagaaa agtaaaactt gtattagggt agccattcac   1980

atcatttttt atagggtaga tcttcatatt gctgtgatta atgcatccag attgttttcc   2040

tagtatttcc aggttagaac ctgtggattg tttcaattgc atatagcttg gtttccataa   2100

catagagcat tggttgactg tttacagaag actcactcac caggataaac attgctgtat   2160

gttacagtaa agctatctgg agagaacaca taaatgattt tggcatacca ttagagaaac   2220

catttgtaaa actcaaatga ccacataaag cttatcaagg agtctagatt ggttttgttt   2280

tataccatat gggatgaaga aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc   2340

cagctgctga aaatagaagt tggctactct cagaatttgg tttaaagctg gacagatttg   2400

ctttgttata gggtaaagct ttgtctaaag tcctcatttt cttttaaaat tgaataaaat   2460

ttctgtatac agattcattg tatgtacctt tattgcttct taagggtcct tgctgtatag   2520

acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt gactcatttg taaatgagca   2580

gaactgtttt gttggttttt ttccctaaat ataaaagtcc acacttcgtt tgtgctataa   2640

cctcaaactt tgatttctaa tgtcacactt aaaactgtgt ggaataagac ttttgccata   2700

aaaataaact atggagtcct ttatctacca gagccttttt ggtttgaccg ccacgattta   2760

ggttagtcag tttaaaaatt gttcatgttg tttggatggt atcgaaaacc agaaaccact   2820

tttaataatg tgtttaagat acttgatttg aagtcctttt catatggact aattgtagta   2880

tcaatttcct cctgtcccga ttatgtgaaa ttttggcctt taaacaaaga ggggcccatt   2940

cataagaaag tgttatatct aggtttttaa aactgaagtt gaaattatct ttgttagcag   3000

tagtagtata gaataaaaga tccgtatgct ggttcgtaga ttgatacgtg ttagtcctgt   3060

tatttggagg ctttttggca tagttgttcg atcaggagcc tgtttactaa aagtcttcat   3120

acagagtaca agtgcagccg ccagaggaga aaattgagat tcttgaccct ttcatactct   3180

tttctttggt attcaggaca ctaaggcagg aggaccacat gagttctggt tggtaagtgt   3240

ccttgtcatg aaaacacttg ccttacaagg ctctaattat gatttcccta gtcagtgctc   3300

tgaagatgtg tcacattata ttataaacaa tacggaaggg gagataggtg agatgatatg   3360

aaaaacaaat tttctcactg tcataaaagg ctctaattat ggttactttc cttgtgatga   3420

aaaacttggc cttacagggc tctagttatg gttactttcc ctagtcaatg ctctgaaaat   3480

gtgtcacatt ataaacaata cagaaggaga gatagatgag agatcatgaa aaccaaattt   3540

tatcttttac atggcccctt tgtcttcgtt tgaaacatcc ccaacatttc ctacaaatca   3600

gcgtagttac aaaggggtca gtcttttaaa ataagtattt cctattaaac tatatatata   3660

tacagtgcct ttttggtgtt gtgagtcagt ggaacactga aatacagcgg ttgtgtaatt   3720

taagagtggc aacagtttca tttgataaga tttgaaaagg ctttttatca ctacaatctt   3780

agaggattga cagtacagga tttttgttta agagaaggat tgtttagact caagaggtga   3840

ctatgttgtg ggtcttttga taattcatga atacagattt gctttgaccg atcactagat   3900

actgcctcct caatttcaaa agcaatataa cgtttgtata tgctgtttaa tttaagttaa   3960

tgttaagtaa tcatttctca ttccaaagac aatgcaaaaa acttcagcac tgcttgagag   4020

ttgtatttca gccacagata ttttctccat tggaaagcta ttttcatttt agaaaaatgg   4080

gttgtttgaa gatgaaagtc ttttatcttt tttcacaatt tattttggtt atatgttcgt   4140

acattcttat taaatatttc atacacttta ttgcaactac tttgttattt ctacatctta   4200

gataaatgct gaaaaggaaa acgatttcat tgttcatcta attaaataaa ttaaaagagc   4260

ggtttgtgta gaaattggag agaactatgt tttatatgaa tcacaacagt gctcgttgtg   4320

gactgtaatt aaatgctttg ccctctggaa cttgattttt gtgtatctga gatttattaa   4380

cagtgctaac tgctaaggat actgtttatc ttgttctggg cattggagtt tcagttttta   4440

aaaaattctt gaaaatgtat tctgtgaaac tactcatacc tctcttcctg cgaattttct   4500

cctaagaact aggtttgggg tagaaatgaa ttgacattat tttctcattt gctttgtatg   4560

gtatgaagga tttgtaaagc tttgctcaaa gttgtgtgca tttgtaaaca ctatcatgat   4620

attttcaatt ttatgtgtaa attttattgt ctgtttttgg tgactctgac attaatggaa   4680

gagaatattt tccattagat ttaatttttt ttcctctccc ttctgatttt ttttttattg   4740

gtgttcattt ttcttttgat ttaaaggatt agagaaatct acaaatgtat gtcataaata   4800

agcaaatttg taaacttttc tgaactttag tgaaacattt agttcacaag cataatttgg   4860

aggtgtgttc tgtgtttaca cagtagtttg gatgtacaat tattattagt ggctttttaa   4920

aaaatgaaac agtgttaagt gaaatgtagt tcctagcttt gtactccaag ttgtcaaagc   4980

atcaacaatg aaaattcgat taggaaactt tatttaaaat ttcaggtagt aatattcagt   5040

gtagttaagg ccagtcttaa cccactggat gaaaatctag gactgtatgg aagtaagcaa   5100

acattacatt tttaggtgga aatagtcagc cttgcataaa aacaaggatg cgtgaaagcc   5160

ttaaattcca gctccctttt actggagtct gtggttgtgt acaggtatgg gccaagtgta   5220

aaatctcatc aattttaaga acactcggga aatgagtaaa gaaaatgtaa aattgctgct   5280

agtcaaatct tttggaaaga atttctggaa gtggtcactt taaaaattat tttccaccct   5340

tgcaaaattg ccacatttaa attgttttac tggcagttct atagtagtcc agactttaga   5400

aaccaaacac aacaaaatgg cttgttgcca atatggccac aacattgcca gcaaatactg   5460

ccttggcatc actcagcaga ggtttttgtt tataaagatg aagtcttgaa tactgttcaa   5520

taaacttgtc                                                          5530


<210>  9712
<211>  404
<212>  PRT
<213>  Homo sapiens

<400>  9712

Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro Pro 
1               5                   10                  15


Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro Met 
            20                  25                  30


Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn Pro 
        35                  40                  45


Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro 
    50                  55                  60


Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe Ser 
65                  70                  75                  80


Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val Asp 
                85                  90                  95


Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly 
            100                 105                 110


Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg 
        115                 120                 125


Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr 
    130                 135                 140


Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn 
145                 150                 155                 160


Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg 
                165                 170                 175


Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His 
            180                 185                 190


Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu 
        195                 200                 205


Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp 
    210                 215                 220


Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly 
225                 230                 235                 240


Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg 
                245                 250                 255


His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr 
            260                 265                 270


Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu Gln 
        275                 280                 285


Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly Asp 
    290                 295                 300


Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe Ser 
305                 310                 315                 320


Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val Asp 
                325                 330                 335


Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu Gly 
            340                 345                 350


Gln Ala Leu Val Gln Asn Ala Gln Cys Gly Thr Ala Arg Cys Gly Thr 
        355                 360                 365


Ala Gln Cys Arg Thr Ser Arg Cys Arg Pro Ala Gln His Arg Thr Ala 
    370                 375                 380


Trp Phe Ser Asn Asn Gln Cys Arg Thr Ala Trp Cys Gly Asn Ala Gln 
385                 390                 395                 400


Cys Arg Asn Thr 



<210>  9713
<211>  6286
<212>  DNA
<213>  Homo sapiens

<400>  9713
caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc cgtttgcaag gtctcccaat     60

tgtggcgggg accatggaca ttcgccactt cttctctgga ttgaccattc ctgatggggg    120

cgtgcatatt gtagggggtg aactgggtga ggctttcatc gtttttgcca ctgatgaaga    180

tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa gggtcaaaag taacactatt    240

gttgagtagt aagacggaaa tgcagaatat gattgaactg agtcgtaggc gttttgaaac    300

tgccaactta gatataccac cagcaaatgc cagtagatca ggaccaccac ctagctcagg    360

aatgagtagc agggtaaact tgcccacaac agtatccaac tttaataatc catcacccag    420

tgtagttact gccaccactt ctgttcatga aagcaacaaa aacatacaga cattttccac    480

agccagcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc caacgtttag    540

ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac caattcctcc    600

aattccagcg atgccatctt ctgtgccacc catgacccca ctgccaccca tgtcgggcat    660

gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg gctctggagc    720

acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga atcctgttaa    780

ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc ctgatgatct    840

gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca gagatttttt    900

tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc gaaataatgg    960

gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga aacgaaacag   1020

aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac agtgggtagc   1080

tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa ctcatccccc   1140

tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc   1200

accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag cagaaaacaa   1260

acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt atatagctta   1320

tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg aggctgacta   1380

taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc aagttcatcc   1440

aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac tgcagaactt   1500

cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact ctgccaaagt   1560

ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc ttcagttcct   1620

agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca atgggcaagg   1680

tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt   1740

acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc tagaagatat   1800

gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc   1860

aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg gactgcccag   1920

tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag caataaccag   1980

tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag gaggtgaaga   2040

gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat ttaactttcc   2100

tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag gattaggagg   2160

cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg   2220

tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg ggccatcggg   2280

atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg gtcccccggg   2340

gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg ggccaccagc   2400

ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg gtggtccccc   2460

tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc aaaacatgcc   2520

ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag taatcccagg   2580

ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt   2640

tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc ctataggttc   2700

aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag ggtagatctt   2760

catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt tagaacctgt   2820

ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt tgactgttta   2880

cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct atctggagag   2940

aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc aaatgaccac   3000

ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga tgaagaaaat   3060

agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat agaagttggc   3120

tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt aaagctttgt   3180

ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat tcattgtatg   3240

tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca gaagttgctg   3300

ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg gtttttttcc   3360

ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat ttctaatgtc   3420

acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg agtcctttat   3480

ctaccagagc ctttttggtt tgaccgccac gatttaggtt agtcagttta aaaattgttc   3540

atgttgtttg gatggtatcg aaaaccagaa accactttta ataatgtgtt taagatactt   3600

gatttgaagt ccttttcata tggactaatt gtagtatcaa tttcctcctg tcccgattat   3660

gtgaaatttt ggcctttaaa caaagagggg cccattcata agaaagtgtt atatctaggt   3720

ttttaaaact gaagttgaaa ttatctttgt tagcagtagt agtatagaat aaaagatccg   3780

tatgctggtt cgtagattga tacgtgttag tcctgttatt tggaggcttt ttggcatagt   3840

tgttcgatca ggagcctgtt tactaaaagt cttcatacag agtacaagtg cagccgccag   3900

aggagaaaat tgagattctt gaccctttca tactcttttc tttggtattc aggacactaa   3960

ggcaggagga ccacatgagt tctggttggt aagtgtcctt gtcatgaaaa cacttgcctt   4020

acaaggctct aattatgatt tccctagtca gtgctctgaa gatgtgtcac attatattat   4080

aaacaatacg gaaggggaga taggtgagat gatatgaaaa acaaattttc tcactgtcat   4140

aaaaggctct aattatggtt actttccttg tgatgaaaaa cttggcctta cagggctcta   4200

gttatggtta ctttccctag tcaatgctct gaaaatgtgt cacattataa acaatacaga   4260

aggagagata gatgagagat catgaaaacc aaattttatc ttttacatgg cccctttgtc   4320

ttcgtttgaa acatccccaa catttcctac aaatcagcgt agttacaaag gggtcagtct   4380

tttaaaataa gtatttccta ttaaactata tatatataca gtgccttttt ggtgttgtga   4440

gtcagtggaa cactgaaata cagcggttgt gtaatttaag agtggcaaca gtttcatttg   4500

ataagatttg aaaaggcttt ttatcactac aatcttagag gattgacagt acaggatttt   4560

tgtttaagag aaggattgtt tagactcaag aggtgactat gttgtgggtc ttttgataat   4620

tcatgaatac agatttgctt tgaccgatca ctagatactg cctcctcaat ttcaaaagca   4680

atataacgtt tgtatatgct gtttaattta agttaatgtt aagtaatcat ttctcattcc   4740

aaagacaatg caaaaaactt cagcactgct tgagagttgt atttcagcca cagatatttt   4800

ctccattgga aagctatttt cattttagaa aaatgggttg tttgaagatg aaagtctttt   4860

atcttttttc acaatttatt ttggttatat gttcgtacat tcttattaaa tatttcatac   4920

actttattgc aactactttg ttatttctac atcttagata aatgctgaaa aggaaaacga   4980

tttcattgtt catctaatta aataaattaa aagagcggtt tgtgtagaaa ttggagagaa   5040

ctatgtttta tatgaatcac aacagtgctc gttgtggact gtaattaaat gctttgccct   5100

ctggaacttg atttttgtgt atctgagatt tattaacagt gctaactgct aaggatactg   5160

tttatcttgt tctgggcatt ggagtttcag tttttaaaaa attcttgaaa atgtattctg   5220

tgaaactact catacctctc ttcctgcgaa ttttctccta agaactaggt ttggggtaga   5280

aatgaattga cattattttc tcatttgctt tgtatggtat gaaggatttg taaagctttg   5340

ctcaaagttg tgtgcatttg taaacactat catgatattt tcaattttat gtgtaaattt   5400

tattgtctgt ttttggtgac tctgacatta atggaagaga atattttcca ttagatttaa   5460

ttttttttcc tctcccttct gatttttttt ttattggtgt tcatttttct tttgatttaa   5520

aggattagag aaatctacaa atgtatgtca taaataagca aatttgtaaa cttttctgaa   5580

ctttagtgaa acatttagtt cacaagcata atttggaggt gtgttctgtg tttacacagt   5640

agtttggatg tacaattatt attagtggct ttttaaaaaa tgaaacagtg ttaagtgaaa   5700

tgtagttcct agctttgtac tccaagttgt caaagcatca acaatgaaaa ttcgattagg   5760

aaactttatt taaaatttca ggtagtaata ttcagtgtag ttaaggccag tcttaaccca   5820

ctggatgaaa atctaggact gtatggaagt aagcaaacat tacattttta ggtggaaata   5880

gtcagccttg cataaaaaca aggatgcgtg aaagccttaa attccagctc ccttttactg   5940

gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat ctcatcaatt ttaagaacac   6000

tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc aaatcttttg gaaagaattt   6060

ctggaagtgg tcactttaaa aattattttc cacccttgca aaattgccac atttaaattg   6120

ttttactggc agttctatag tagtccagac tttagaaacc aaacacaaca aaatggcttg   6180

ttgccaatat ggccacaaca ttgccagcaa atactgcctt ggcatcactc agcagaggtt   6240

tttgtttata aagatgaagt cttgaatact gttcaataaa cttgtc                  6286


<210>  9714
<211>  900
<212>  PRT
<213>  Homo sapiens

<400>  9714

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
        195                 200                 205


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
    210                 215                 220


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
225                 230                 235                 240


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
                245                 250                 255


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
            260                 265                 270


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
        275                 280                 285


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
    290                 295                 300


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
305                 310                 315                 320


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
                325                 330                 335


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
            340                 345                 350


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
        355                 360                 365


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
    370                 375                 380


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
385                 390                 395                 400


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
                405                 410                 415


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
            420                 425                 430


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
        435                 440                 445


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
    450                 455                 460


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
465                 470                 475                 480


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
                485                 490                 495


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
            500                 505                 510


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
        515                 520                 525


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
    530                 535                 540


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
545                 550                 555                 560


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
                565                 570                 575


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
            580                 585                 590


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
        595                 600                 605


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
    610                 615                 620


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
625                 630                 635                 640


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
                645                 650                 655


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
            660                 665                 670


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
        675                 680                 685


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
    690                 695                 700


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
705                 710                 715                 720


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
                725                 730                 735


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
            740                 745                 750


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
        755                 760                 765


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
    770                 775                 780


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
785                 790                 795                 800


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
                805                 810                 815


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
            820                 825                 830


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
        835                 840                 845


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
    850                 855                 860


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
865                 870                 875                 880


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
                885                 890                 895


Leu Val Leu Gly 
            900


<210>  9715
<211>  6548
<212>  DNA
<213>  Homo sapiens

<400>  9715
gaaatgcctc cgaggtccat tgctggggag gggctttact cgagggtgta gcagttttga     60

gaagccggcg tctgaagcta ggagtctaaa agttggtttt aattggttgc ccacaggatt    120

gacttggcct ctacttcttg ttaaggaaat tcatctcttg ttttatcagg tgtgtgtggt    180

ttcagcgcag catggctgtg gtcatccgtt tgcaaggtct cccaattgtg gcggggacca    240

tggacattcg ccacttcttc tctggattga ccattcctga tgggggcgtg catattgtag    300

ggggtgaact gggtgaggct ttcatcgttt ttgccactga tgaagatgca aggcttggta    360

tgatgcgcac aggtggtaca attaaagggt caaaagtaac actattgttg agtagtaaga    420

cggaaatgca gaatatgatt gaactgagtc gtaggcgttt tgaaactgcc aacttagata    480

taccaccagc aaatgccagt agatcaggac caccacctag ctcaggaatg agtagcaggg    540

taaacttgcc cacaacagta tccaacttta ataatccatc acccagtgta gttactgcca    600

ccacttctgt tcatgaaagc aacaaaaaca tacagacatt ttccacagcc agcgtaggaa    660

cagctcctcc aaatatgggg gcttcctttg ggagcccaac gtttagctca actgttccaa    720

gcacagcctc tccaatgaac acagtcccgc cgccaccaat tcctccaatt ccagcgatgc    780

catctctgcc accaatgcca tccattcccc caattccagt tcctcctcca gtacctacat    840

tgcctcctgt gcctcctgtg cccccgattc ccccagttcc ttctgtgcca cccatgaccc    900

cactgccacc catgtcgggc atgccgccct tgaatccgcc acctgtggca cctctacctg    960

ctggaatgaa tggctctgga gcacctatga atttgaacaa taatctgaat cctatgtttc   1020

ttggtccgtt gaatcctgtt aaccctatcc agatgaactc tcagagcagt gtgaagccac   1080

tccccatcaa ccctgatgat ctgtatgtca gtgtgcatgg aatgcccttt tctgcaatgg   1140

aaaatgatgt cagagatttt tttcatgggc tccgtgttga tgcagtgcat ttgttgaaag   1200

atcatgtagg tcgaaataat gggaatggat tggttaagtt tctctcccct caagatacat   1260

ttgaagcttt gaaacgaaac agaatgctga tgattcaacg ctatgtggaa gttagccctg   1320

ccacagaaag acagtgggta gctgctggag gccatatcac ttttaagcaa aatatgggac   1380

cttctggaca aactcatccc cctcctcaga cacttcccag gtcaaaatcg cccagtgggc   1440

agaaaagatc aaggtcaaga tcaccacatg aggctggttt ttgtgtttac ttgaaagggc   1500

taccatttga agcagaaaac aaacatgtca ttgatttttt taaaaagctg gatattgtgg   1560

aagatagtat ttatatagct tatggaccca atgggaaagc aactggcgaa ggctttgtag   1620

agttcagaaa tgaggctgac tataaggctg ctctgtgtcg tcataaacag tacatgggca   1680

atcgctttat tcaagttcat ccaattacta agaaaggtat gctagaaaag atagatatga   1740

ttcgaaaaag actgcagaac ttcagctatg accagaggga aatgatacta aatccagagg   1800

gggatgtcaa ctctgccaaa gtctgtgccc acataacaaa tattccattc agcattacaa   1860

agatggatgt tcttcagttc ctagaaggaa tcccagtgga tgaaaatgct gtacatgttc   1920

ttgttgataa caatgggcaa ggtctaggac aggcattggt tcagtttaaa aatgaagatg   1980

atgcacgtaa gtctgaacgc ttacaccgta aaaaacttaa tgggagagaa gcttttgttc   2040

atgtagttac cctagaagat atgagagaga ttgagaaaaa tccccctgcc caaggaaaaa   2100

agggattaaa gatgcctgtg ccaggtaatc ctgcagttcc aggaatgccc aatgcgggac   2160

tgcccggtgt gggactgccc agtgcaggac ttcccggtgc aggcctgccc agcacaggac   2220

tgcctggttc agcaataacc agtgcaggac tgcctggtgc gggaatgccc agtgcaggaa   2280

tacctagtgc aggaggtgaa gagcatgcct tcctgactgt aggatcaaag gaagccaata   2340

atgggcctcc atttaacttt cctggtaatt ttggtggatc aaatgccttt gggccaccaa   2400

tccctcctcc aggattagga ggcggggcct ttggtgatgc taggcctggt atgccttcag   2460

ttggaaacag tggtttgcct ggtctaggac tggatgttcc gggttttgga ggtggaccaa   2520

acaatttaag tgggccatcg ggatttggag ggggccctca gaattttgga aatggccctg   2580

gtagcttagg cggtcccccg gggtttggaa gtggccctcc tggtcttgga agtgcccctg   2640

ggcatttggg tgggccacca gcttttgggc ctggccccgg ccccggcccc ggccctggcc   2700

caatccatat tggtggtccc cctggctttg catctagttc tggaaaacca ggaccgacag   2760

taattaaagt gcaaaacatg ccctttactg tgtctattga tgagatttta gatttctttt   2820

atggctatca agtaatccca ggctcagtgt gtttaaaata caatgaaaaa ggtatgccca   2880

caggtgaagc catggtggcc tttgagtctc gggatgaagc cacagctgct gtcattgact   2940

taaatgacag gcctataggt tcaagaaaag taaaacttgt attagggtag ccattcacat   3000

cattttttat agggtagatc ttcatattgc tgtgattaat gcatccagat tgttttccta   3060

gtatttccag gttagaacct gtggattgtt tcaattgcat atagcttggt ttccataaca   3120

tagagcattg gttgactgtt tacagaagac tcactcacca ggataaacat tgctgtatgt   3180

tacagtaaag ctatctggag agaacacata aatgattttg gcataccatt agagaaacca   3240

tttgtaaaac tcaaatgacc acataaagct tatcaaggag tctagattgg ttttgtttta   3300

taccatatgg gatgaagaaa atagaaatgt cagtagaact cattgagggt gctcttgcca   3360

gctgctgaaa atagaagttg gctactctca gaatttggtt taaagctgga cagatttgct   3420

ttgttatagg gtaaagcttt gtctaaagtc ctcattttct tttaaaattg aataaaattt   3480

ctgtatacag attcattgta tgtaccttta ttgcttctta agggtccttg ctgtatagac   3540

agtcctgctt cagaagttgc tgctttgttt gtctaattga ctcatttgta aatgagcaga   3600

actgttttgt tggttttttt ccctaaatat aaaagtccac acttcgtttg tgctataacc   3660

tcaaactttg atttctaatg tcacacttaa aactgtgtgg aataagactt ttgccataaa   3720

aataaactat ggagtccttt atctaccaga gcctttttgg tttgaccgcc acgatttagg   3780

ttagtcagtt taaaaattgt tcatgttgtt tggatggtat cgaaaaccag aaaccacttt   3840

taataatgtg tttaagatac ttgatttgaa gtccttttca tatggactaa ttgtagtatc   3900

aatttcctcc tgtcccgatt atgtgaaatt ttggccttta aacaaagagg ggcccattca   3960

taagaaagtg ttatatctag gtttttaaaa ctgaagttga aattatcttt gttagcagta   4020

gtagtataga ataaaagatc cgtatgctgg ttcgtagatt gatacgtgtt agtcctgtta   4080

tttggaggct ttttggcata gttgttcgat caggagcctg tttactaaaa gtcttcatac   4140

agagtacaag tgcagccgcc agaggagaaa attgagattc ttgacccttt catactcttt   4200

tctttggtat tcaggacact aaggcaggag gaccacatga gttctggttg gtaagtgtcc   4260

ttgtcatgaa aacacttgcc ttacaaggct ctaattatga tttccctagt cagtgctctg   4320

aagatgtgtc acattatatt ataaacaata cggaagggga gataggtgag atgatatgaa   4380

aaacaaattt tctcactgtc ataaaaggct ctaattatgg ttactttcct tgtgatgaaa   4440

aacttggcct tacagggctc tagttatggt tactttccct agtcaatgct ctgaaaatgt   4500

gtcacattat aaacaataca gaaggagaga tagatgagag atcatgaaaa ccaaatttta   4560

tcttttacat ggcccctttg tcttcgtttg aaacatcccc aacatttcct acaaatcagc   4620

gtagttacaa aggggtcagt cttttaaaat aagtatttcc tattaaacta tatatatata   4680

cagtgccttt ttggtgttgt gagtcagtgg aacactgaaa tacagcggtt gtgtaattta   4740

agagtggcaa cagtttcatt tgataagatt tgaaaaggct ttttatcact acaatcttag   4800

aggattgaca gtacaggatt tttgtttaag agaaggattg tttagactca agaggtgact   4860

atgttgtggg tcttttgata attcatgaat acagatttgc tttgaccgat cactagatac   4920

tgcctcctca atttcaaaag caatataacg tttgtatatg ctgtttaatt taagttaatg   4980

ttaagtaatc atttctcatt ccaaagacaa tgcaaaaaac ttcagcactg cttgagagtt   5040

gtatttcagc cacagatatt ttctccattg gaaagctatt ttcattttag aaaaatgggt   5100

tgtttgaaga tgaaagtctt ttatcttttt tcacaattta ttttggttat atgttcgtac   5160

attcttatta aatatttcat acactttatt gcaactactt tgttatttct acatcttaga   5220

taaatgctga aaaggaaaac gatttcattg ttcatctaat taaataaatt aaaagagcgg   5280

tttgtgtaga aattggagag aactatgttt tatatgaatc acaacagtgc tcgttgtgga   5340

ctgtaattaa atgctttgcc ctctggaact tgatttttgt gtatctgaga tttattaaca   5400

gtgctaactg ctaaggatac tgtttatctt gttctgggca ttggagtttc agtttttaaa   5460

aaattcttga aaatgtattc tgtgaaacta ctcatacctc tcttcctgcg aattttctcc   5520

taagaactag gtttggggta gaaatgaatt gacattattt tctcatttgc tttgtatggt   5580

atgaaggatt tgtaaagctt tgctcaaagt tgtgtgcatt tgtaaacact atcatgatat   5640

tttcaatttt atgtgtaaat tttattgtct gtttttggtg actctgacat taatggaaga   5700

gaatattttc cattagattt aatttttttt cctctccctt ctgatttttt ttttattggt   5760

gttcattttt cttttgattt aaaggattag agaaatctac aaatgtatgt cataaataag   5820

caaatttgta aacttttctg aactttagtg aaacatttag ttcacaagca taatttggag   5880

gtgtgttctg tgtttacaca gtagtttgga tgtacaatta ttattagtgg ctttttaaaa   5940

aatgaaacag tgttaagtga aatgtagttc ctagctttgt actccaagtt gtcaaagcat   6000

caacaatgaa aattcgatta ggaaacttta tttaaaattt caggtagtaa tattcagtgt   6060

agttaaggcc agtcttaacc cactggatga aaatctagga ctgtatggaa gtaagcaaac   6120

attacatttt taggtggaaa tagtcagcct tgcataaaaa caaggatgcg tgaaagcctt   6180

aaattccagc tcccttttac tggagtctgt ggttgtgtac aggtatgggc caagtgtaaa   6240

atctcatcaa ttttaagaac actcgggaaa tgagtaaaga aaatgtaaaa ttgctgctag   6300

tcaaatcttt tggaaagaat ttctggaagt ggtcacttta aaaattattt tccacccttg   6360

caaaattgcc acatttaaat tgttttactg gcagttctat agtagtccag actttagaaa   6420

ccaaacacaa caaaatggct tgttgccaat atggccacaa cattgccagc aaatactgcc   6480

ttggcatcac tcagcagagg tttttgttta taaagatgaa gtcttgaata ctgttcaata   6540

aacttgtc                                                            6548


<210>  9716
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9716

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9717
<211>  6032
<212>  DNA
<213>  Homo sapiens

<400>  9717
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc    180

caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac    240

caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt cccccaattc    300

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    360

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    420

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    480

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    540

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    600

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    660

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    720

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    780

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    840

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    900

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    960

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt   1020

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1080

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1140

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1200

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1260

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1320

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1380

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1440

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1500

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1560

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1620

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1680

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1740

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1800

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1860

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1920

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1980

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   2040

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2100

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2160

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2220

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2280

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2340

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2400

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2460

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2520

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2580

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2640

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2700

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2760

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2820

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2880

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2940

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   3000

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3060

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3120

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3180

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3240

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3300

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3360

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3420

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3480

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3540

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3600

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3660

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3720

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3780

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3840

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3900

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3960

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   4020

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4080

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4140

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4200

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4260

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4320

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4380

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4440

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4500

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4560

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4620

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgcaact   4680

actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc attgttcatc   4740

taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat gttttatatg   4800

aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg aacttgattt   4860

ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta tcttgttctg   4920

ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa actactcata   4980

cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg aattgacatt   5040

attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca aagttgtgtg   5100

catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt gtctgttttt   5160

ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt ttttcctctc   5220

ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga ttagagaaat   5280

ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt agtgaaacat   5340

ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt tggatgtaca   5400

attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta gttcctagct   5460

ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac tttatttaaa   5520

atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg atgaaaatct   5580

aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca gccttgcata   5640

aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt ctgtggttgt   5700

gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg gaaatgagta   5760

aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg aagtggtcac   5820

tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt actggcagtt   5880

ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc caatatggcc   5940

acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg tttataaaga   6000

tgaagtcttg aatactgttc aataaacttg tc                                 6032


<210>  9718
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9718

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9719
<211>  6066
<212>  DNA
<213>  Homo sapiens

<400>  9719
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg tgttccaagc    240

acagcctctc caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca    300

tctctgccac caatgccatc cattccccca attccagttc ctcctccagt acctacattg    360

cctcctgtgc ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca    420

ctgccaccca tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct    480

ggaatgaatg gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt    540

ggtccgttga atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc    600

cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa    660

aatgatgtca gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat    720

catgtaggtc gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt    780

gaagctttga aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc    840

acagaaagac agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct    900

tctggacaaa ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag    960

aaaagatcaa ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta   1020

ccatttgaag cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa   1080

gatagtattt atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag   1140

ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat   1200

cgctttattc aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt   1260

cgaaaaagac tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg   1320

gatgtcaact ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag   1380

atggatgttc ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt   1440

gttgataaca atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat   1500

gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat   1560

gtagttaccc tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag   1620

ggattaaaga tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg   1680

cccggtgtgg gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg   1740

cctggttcag caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata   1800

cctagtgcag gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat   1860

gggcctccat ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc   1920

cctcctccag gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt   1980

ggaaacagtg gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac   2040

aatttaagtg ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt   2100

agcttaggcg gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg   2160

catttgggtg ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca   2220

atccatattg gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta   2280

attaaagtgc aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat   2340

ggctatcaag taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca   2400

ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta   2460

aatgacaggc ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca   2520

ttttttatag ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt   2580

atttccaggt tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata   2640

gagcattggt tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta   2700

cagtaaagct atctggagag aacacataaa tgattttggc ataccattag agaaaccatt   2760

tgtaaaactc aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata   2820

ccatatggga tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc   2880

tgctgaaaat agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt   2940

gttatagggt aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct   3000

gtatacagat tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag   3060

tcctgcttca gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac   3120

tgttttgttg gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc   3180

aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa   3240

taaactatgg agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt   3300

agtcagttta aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta   3360

ataatgtgtt taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa   3420

tttcctcctg tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata   3480

agaaagtgtt atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt   3540

agtatagaat aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt   3600

tggaggcttt ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag   3660

agtacaagtg cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc   3720

tttggtattc aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt   3780

gtcatgaaaa cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa   3840

gatgtgtcac attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa   3900

acaaattttc tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa   3960

cttggcctta cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt   4020

cacattataa acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc   4080

ttttacatgg cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt   4140

agttacaaag gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca   4200

gtgccttttt ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag   4260

agtggcaaca gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag   4320

gattgacagt acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat   4380

gttgtgggtc ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg   4440

cctcctcaat ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt   4500

aagtaatcat ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt   4560

atttcagcca cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg   4620

tttgaagatg aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat   4680

tcttattaaa tatttcatac actttattgc aactactttg ttatttctac atcttagata   4740

aatgctgaaa aggaaaacga tttcattgtt catctaatta aataaattaa aagagcggtt   4800

tgtgtagaaa ttggagagaa ctatgtttta tatgaatcac aacagtgctc gttgtggact   4860

gtaattaaat gctttgccct ctggaacttg atttttgtgt atctgagatt tattaacagt   4920

gctaactgct aaggatactg tttatcttgt tctgggcatt ggagtttcag tttttaaaaa   4980

attcttgaaa atgtattctg tgaaactact catacctctc ttcctgcgaa ttttctccta   5040

agaactaggt ttggggtaga aatgaattga cattattttc tcatttgctt tgtatggtat   5100

gaaggatttg taaagctttg ctcaaagttg tgtgcatttg taaacactat catgatattt   5160

tcaattttat gtgtaaattt tattgtctgt ttttggtgac tctgacatta atggaagaga   5220

atattttcca ttagatttaa ttttttttcc tctcccttct gatttttttt ttattggtgt   5280

tcatttttct tttgatttaa aggattagag aaatctacaa atgtatgtca taaataagca   5340

aatttgtaaa cttttctgaa ctttagtgaa acatttagtt cacaagcata atttggaggt   5400

gtgttctgtg tttacacagt agtttggatg tacaattatt attagtggct ttttaaaaaa   5460

tgaaacagtg ttaagtgaaa tgtagttcct agctttgtac tccaagttgt caaagcatca   5520

acaatgaaaa ttcgattagg aaactttatt taaaatttca ggtagtaata ttcagtgtag   5580

ttaaggccag tcttaaccca ctggatgaaa atctaggact gtatggaagt aagcaaacat   5640

tacattttta ggtggaaata gtcagccttg cataaaaaca aggatgcgtg aaagccttaa   5700

attccagctc ccttttactg gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat   5760

ctcatcaatt ttaagaacac tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc   5820

aaatcttttg gaaagaattt ctggaagtgg tcactttaaa aattattttc cacccttgca   5880

aaattgccac atttaaattg ttttactggc agttctatag tagtccagac tttagaaacc   5940

aaacacaaca aaatggcttg ttgccaatat ggccacaaca ttgccagcaa atactgcctt   6000

ggcatcactc agcagaggtt tttgtttata aagatgaagt cttgaatact gttcaataaa   6060

cttgtc                                                              6066


<210>  9720
<211>  751
<212>  PRT
<213>  Homo sapiens

<400>  9720

Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro 
1               5                   10                  15


Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro 
            20                  25                  30


Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val 
        35                  40                  45


Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro 
    50                  55                  60


Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly 
65                  70                  75                  80


Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu 
                85                  90                  95


Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser 
            100                 105                 110


Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His 
        115                 120                 125


Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His 
    130                 135                 140


Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg 
145                 150                 155                 160


Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe 
                165                 170                 175


Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu 
            180                 185                 190


Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile 
        195                 200                 205


Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro 
    210                 215                 220


Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg 
225                 230                 235                 240


Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu 
                245                 250                 255


Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu 
            260                 265                 270


Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys 
        275                 280                 285


Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys 
    290                 295                 300


Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln 
305                 310                 315                 320


Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile 
                325                 330                 335


Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu 
            340                 345                 350


Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr 
        355                 360                 365


Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu 
    370                 375                 380


Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn 
385                 390                 395                 400


Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp 
                405                 410                 415


Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu 
            420                 425                 430


Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys 
        435                 440                 445


Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly 
    450                 455                 460


Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly 
465                 470                 475                 480


Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu 
                485                 490                 495


Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro 
            500                 505                 510


Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr 
        515                 520                 525


Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly 
    530                 535                 540


Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly 
545                 550                 555                 560


Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val 
                565                 570                 575


Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly 
            580                 585                 590


Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro 
        595                 600                 605


Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe 
    610                 615                 620


Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly 
625                 630                 635                 640


Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
                645                 650                 655


Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro 
            660                 665                 670


Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile 
        675                 680                 685


Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser 
    690                 695                 700


Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met 
705                 710                 715                 720


Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu 
                725                 730                 735


Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
            740                 745                 750


<210>  9721
<211>  5972
<212>  DNA
<213>  Homo sapiens

<400>  9721
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatcttc tgccaccaat gccatccatt cccccaattc    240

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    300

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    360

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    420

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    480

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    540

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    600

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    660

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    720

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    780

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    840

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    900

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt    960

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1020

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1080

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1140

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1200

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1260

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1320

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1380

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1440

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1500

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1560

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1620

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1680

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1740

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1800

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1860

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1920

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   1980

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2040

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2100

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2160

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2220

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2280

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2340

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2400

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2460

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2520

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2580

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2640

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2700

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2760

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2820

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2880

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   2940

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3000

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3060

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3120

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3180

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3240

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3300

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3360

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3420

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3480

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3540

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3600

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3660

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3720

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3780

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3840

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3900

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   3960

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4020

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4080

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4140

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4200

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4260

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4320

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4380

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4440

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4500

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4560

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgcaact   4620

actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc attgttcatc   4680

taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat gttttatatg   4740

aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg aacttgattt   4800

ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta tcttgttctg   4860

ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa actactcata   4920

cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg aattgacatt   4980

attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca aagttgtgtg   5040

catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt gtctgttttt   5100

ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt ttttcctctc   5160

ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga ttagagaaat   5220

ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt agtgaaacat   5280

ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt tggatgtaca   5340

attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta gttcctagct   5400

ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac tttatttaaa   5460

atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg atgaaaatct   5520

aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca gccttgcata   5580

aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt ctgtggttgt   5640

gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg gaaatgagta   5700

aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg aagtggtcac   5760

tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt actggcagtt   5820

ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc caatatggcc   5880

acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg tttataaaga   5940

tgaagtcttg aatactgttc aataaacttg tc                                 5972


<210>  9722
<211>  731
<212>  PRT
<213>  Homo sapiens

<400>  9722

Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr Leu 
1               5                   10                  15


Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val Pro 
            20                  25                  30


Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro 
        35                  40                  45


Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro 
    50                  55                  60


Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn 
65                  70                  75                  80


Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu 
                85                  90                  95


Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe 
            100                 105                 110


Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val 
        115                 120                 125


Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn 
    130                 135                 140


Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys 
145                 150                 155                 160


Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala 
                165                 170                 175


Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln 
            180                 185                 190


Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro 
        195                 200                 205


Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro 
    210                 215                 220


His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala 
225                 230                 235                 240


Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu 
                245                 250                 255


Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu 
            260                 265                 270


Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys 
        275                 280                 285


Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile 
    290                 295                 300


Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu 
305                 310                 315                 320


Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly 
                325                 330                 335


Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe 
            340                 345                 350


Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val 
        355                 360                 365


Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu 
    370                 375                 380


Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys Ser 
385                 390                 395                 400


Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val His 
                405                 410                 415


Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro Ala 
            420                 425                 430


Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala Val 
        435                 440                 445


Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser Ala 
    450                 455                 460


Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser Ala 
465                 470                 475                 480


Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly Ile 
                485                 490                 495


Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser Lys 
            500                 505                 510


Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly Gly 
        515                 520                 525


Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly Gly 
    530                 535                 540


Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser Gly 
545                 550                 555                 560


Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro Asn 
                565                 570                 575


Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe Gly 
            580                 585                 590


Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly Pro 
        595                 600                 605


Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala Phe 
    610                 615                 620


Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile Gly 
625                 630                 635                 640


Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr Val 
                645                 650                 655


Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile Leu 
            660                 665                 670


Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu Lys 
        675                 680                 685


Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe Glu 
    690                 695                 700


Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg Pro 
705                 710                 715                 720


Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
                725                 730


<210>  9723
<211>  6457
<212>  DNA
<213>  Homo sapiens

<400>  9723
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

cattcctgat gggggcgtgc atattgtagg gggtgaactg ggtgaggctt tcatcgtttt    240

tgccactgat gaagatgcaa ggcttggtat gatgcgcaca ggtggtacaa ttaaagggtc    300

aaaagtaaca ctattgttga gtagtaagac ggaaatgcag aatatgattg aactgagtcg    360

taggcgtttt gaaactgcca acttagatat accaccagca aatgccagta gatcaggacc    420

accacctagc tcaggaatga gtagcagggt aaacttgccc acaacagtat ccaactttaa    480

taatccatca cccagtgtag ttactgccac cacttctgtt catgaaagca acaaaaacat    540

acagacattt tccacagcca gcgtaggaac agctcctcca aatatggggg cttcctttgg    600

gagcccaacg tttagctcaa ctgttccaag cacagcctct ccaatgaaca cagtcccgcc    660

gccaccaatt cctccaattc cagcgatgcc atctctgcca ccaatgccat ccattccccc    720

aattccagtt cctcctccag tacctacatt gcctcctgtg cctcctgtgc ccccgattcc    780

cccagttcct tctgtgccac ccatgacccc actgccaccc atgtcgggca tgccgccctt    840

gaatccgcca cctgtggcac ctctacctgc tggaatgaat ggctctggag cacctatgaa    900

tttgaacaat aatctgaatc ctatgtttct tggtccgttg aatcctgtta accctatcca    960

gatgaactct cagagcagtg tgaagccact ccccatcaac cctgatgatc tgtatgtcag   1020

tgtgcatgga atgccctttt ctgcaatgga aaatgatgtc agagattttt ttcatgggct   1080

ccgtgttgat gcagtgcatt tgttgaaaga tcatgtaggt cgaaataatg ggaatggatt   1140

ggttaagttt ctctcccctc aagatacatt tgaagctttg aaacgaaaca gaatgctgat   1200

gattcaacgc tatgtggaag ttagccctgc cacagaaaga cagtgggtag ctgctggagg   1260

ccatatcact tttaagcaaa atatgggacc ttctggacaa actcatcccc ctcctcagac   1320

acttcccagg tcaaaatcgc ccagtgggca gaaaagatca aggtcaagat caccacatga   1380

ggctggtttt tgtgtttact tgaaagggct accatttgaa gcagaaaaca aacatgtcat   1440

tgattttttt aaaaagctgg atattgtgga agatagtatt tatatagctt atggacccaa   1500

tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact ataaggctgc   1560

tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc caattactaa   1620

gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact tcagctatga   1680

ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag tctgtgccca   1740

cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc tagaaggaat   1800

cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag gtctaggaca   1860

ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct tacaccgtaa   1920

aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata tgagagagat   1980

tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc caggtaatcc   2040

tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca gtgcaggact   2100

tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca gtgcaggact   2160

gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag agcatgcctt   2220

cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc ctggtaattt   2280

tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag gcggggcctt   2340

tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg gtctaggact   2400

ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg gatttggagg   2460

gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg ggtttggaag   2520

tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag cttttgggcc   2580

tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc ctggctttgc   2640

atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc cctttactgt   2700

gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag gctcagtgtg   2760

tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct ttgagtctcg   2820

ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt caagaaaagt   2880

aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct tcatattgct   2940

gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg tggattgttt   3000

caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt acagaagact   3060

cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga gaacacataa   3120

atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca cataaagctt   3180

atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa tagaaatgtc   3240

agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg ctactctcag   3300

aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg tctaaagtcc   3360

tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat gtacctttat   3420

tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct gctttgtttg   3480

tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc cctaaatata   3540

aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt cacacttaaa   3600

actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta tctaccagag   3660

cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt catgttgttt   3720

ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact tgatttgaag   3780

tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta tgtgaaattt   3840

tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg tttttaaaac   3900

tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc gtatgctggt   3960

tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag ttgttcgatc   4020

aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca gaggagaaaa   4080

ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta aggcaggagg   4140

accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct tacaaggctc   4200

taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta taaacaatac   4260

ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca taaaaggctc   4320

taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct agttatggtt   4380

actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag aaggagagat   4440

agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt cttcgtttga   4500

aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc ttttaaaata   4560

agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg agtcagtgga   4620

acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt gataagattt   4680

gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt ttgtttaaga   4740

gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa ttcatgaata   4800

cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc aatataacgt   4860

ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc caaagacaat   4920

gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt tctccattgg   4980

aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt tatctttttt   5040

cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata cactttattg   5100

caactacttt gttatttcta catcttagat aaatgctgaa aaggaaaacg atttcattgt   5160

tcatctaatt aaataaatta aaagagcggt ttgtgtagaa attggagaga actatgtttt   5220

atatgaatca caacagtgct cgttgtggac tgtaattaaa tgctttgccc tctggaactt   5280

gatttttgtg tatctgagat ttattaacag tgctaactgc taaggatact gtttatcttg   5340

ttctgggcat tggagtttca gtttttaaaa aattcttgaa aatgtattct gtgaaactac   5400

tcatacctct cttcctgcga attttctcct aagaactagg tttggggtag aaatgaattg   5460

acattatttt ctcatttgct ttgtatggta tgaaggattt gtaaagcttt gctcaaagtt   5520

gtgtgcattt gtaaacacta tcatgatatt ttcaatttta tgtgtaaatt ttattgtctg   5580

tttttggtga ctctgacatt aatggaagag aatattttcc attagattta attttttttc   5640

ctctcccttc tgattttttt tttattggtg ttcatttttc ttttgattta aaggattaga   5700

gaaatctaca aatgtatgtc ataaataagc aaatttgtaa acttttctga actttagtga   5760

aacatttagt tcacaagcat aatttggagg tgtgttctgt gtttacacag tagtttggat   5820

gtacaattat tattagtggc tttttaaaaa atgaaacagt gttaagtgaa atgtagttcc   5880

tagctttgta ctccaagttg tcaaagcatc aacaatgaaa attcgattag gaaactttat   5940

ttaaaatttc aggtagtaat attcagtgta gttaaggcca gtcttaaccc actggatgaa   6000

aatctaggac tgtatggaag taagcaaaca ttacattttt aggtggaaat agtcagcctt   6060

gcataaaaac aaggatgcgt gaaagcctta aattccagct cccttttact ggagtctgtg   6120

gttgtgtaca ggtatgggcc aagtgtaaaa tctcatcaat tttaagaaca ctcgggaaat   6180

gagtaaagaa aatgtaaaat tgctgctagt caaatctttt ggaaagaatt tctggaagtg   6240

gtcactttaa aaattatttt ccacccttgc aaaattgcca catttaaatt gttttactgg   6300

cagttctata gtagtccaga ctttagaaac caaacacaac aaaatggctt gttgccaata   6360

tggccacaac attgccagca aatactgcct tggcatcact cagcagaggt ttttgtttat   6420

aaagatgaag tcttgaatac tgttcaataa acttgtc                            6457


<210>  9724
<211>  876
<212>  PRT
<213>  Homo sapiens

<400>  9724

Met Met Arg Thr Gly Gly Thr Ile Lys Gly Ser Lys Val Thr Leu Leu 
1               5                   10                  15


Leu Ser Ser Lys Thr Glu Met Gln Asn Met Ile Glu Leu Ser Arg Arg 
            20                  25                  30


Arg Phe Glu Thr Ala Asn Leu Asp Ile Pro Pro Ala Asn Ala Ser Arg 
        35                  40                  45


Ser Gly Pro Pro Pro Ser Ser Gly Met Ser Ser Arg Val Asn Leu Pro 
    50                  55                  60


Thr Thr Val Ser Asn Phe Asn Asn Pro Ser Pro Ser Val Val Thr Ala 
65                  70                  75                  80


Thr Thr Ser Val His Glu Ser Asn Lys Asn Ile Gln Thr Phe Ser Thr 
                85                  90                  95


Ala Ser Val Gly Thr Ala Pro Pro Asn Met Gly Ala Ser Phe Gly Ser 
            100                 105                 110


Pro Thr Phe Ser Ser Thr Val Pro Ser Thr Ala Ser Pro Met Asn Thr 
        115                 120                 125


Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro Ser Leu Pro 
    130                 135                 140


Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr 
145                 150                 155                 160


Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val 
                165                 170                 175


Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn 
            180                 185                 190


Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala 
        195                 200                 205


Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu 
    210                 215                 220


Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro 
225                 230                 235                 240


Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro 
                245                 250                 255


Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg 
            260                 265                 270


Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly 
        275                 280                 285


Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu 
    290                 295                 300


Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro 
305                 310                 315                 320


Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys 
                325                 330                 335


Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu 
            340                 345                 350


Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser 
        355                 360                 365


Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu 
    370                 375                 380


Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val 
385                 390                 395                 400


Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly 
                405                 410                 415


Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu 
            420                 425                 430


Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro 
        435                 440                 445


Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg 
    450                 455                 460


Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu 
465                 470                 475                 480


Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro 
                485                 490                 495


Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro 
            500                 505                 510


Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly 
        515                 520                 525


Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys 
    530                 535                 540


Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val 
545                 550                 555                 560


His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro 
                565                 570                 575


Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala 
            580                 585                 590


Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser 
        595                 600                 605


Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser 
    610                 615                 620


Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly 
625                 630                 635                 640


Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser 
                645                 650                 655


Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly 
            660                 665                 670


Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly 
        675                 680                 685


Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser 
    690                 695                 700


Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro 
705                 710                 715                 720


Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe 
                725                 730                 735


Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly 
            740                 745                 750


Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala 
        755                 760                 765


Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile 
    770                 775                 780


Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr 
785                 790                 795                 800


Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile 
                805                 810                 815


Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu 
            820                 825                 830


Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe 
        835                 840                 845


Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg 
    850                 855                 860


Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
865                 870                 875


<210>  9725
<211>  6141
<212>  DNA
<213>  Homo sapiens

<400>  9725
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg gtttcagcgc    240

accagcgtag gaacagctcc tccaaatatg ggggcttcct ttgggagccc aacgtttagc    300

tcaactgttc caagcacagc ctctccaatg aacacagtcc cgccgccacc aattcctcca    360

attccagcga tgccatctct gccaccaatg ccatccattc ccccaattcc agttcctcct    420

ccagtaccta cattgcctcc tgtgcctcct gtgcccccga ttcccccagt tccttctgtg    480

ccacccatga ccccactgcc acccatgtcg ggcatgccgc ccttgaatcc gccacctgtg    540

gcacctctac ctgctggaat gaatggctct ggagcaccta tgaatttgaa caataatctg    600

aatcctatgt ttcttggtcc gttgaatcct gttaacccta tccagatgaa ctctcagagc    660

agtgtgaagc cactccccat caaccctgat gatctgtatg tcagtgtgca tggaatgccc    720

ttttctgcaa tggaaaatga tgtcagagat ttttttcatg ggctccgtgt tgatgcagtg    780

catttgttga aagatcatgt aggtcgaaat aatgggaatg gattggttaa gtttctctcc    840

cctcaagata catttgaagc tttgaaacga aacagaatgc tgatgattca acgctatgtg    900

gaagttagcc ctgccacaga aagacagtgg gtagctgctg gaggccatat cacttttaag    960

caaaatatgg gaccttctgg acaaactcat ccccctcctc agacacttcc caggtcaaaa   1020

tcgcccagtg ggcagaaaag atcaaggtca agatcaccac atgaggctgg tttttgtgtt   1080

tacttgaaag ggctaccatt tgaagcagaa aacaaacatg tcattgattt ttttaaaaag   1140

ctggatattg tggaagatag tatttatata gcttatggac ccaatgggaa agcaactggc   1200

gaaggctttg tagagttcag aaatgaggct gactataagg ctgctctgtg tcgtcataaa   1260

cagtacatgg gcaatcgctt tattcaagtt catccaatta ctaagaaagg tatgctagaa   1320

aagatagata tgattcgaaa aagactgcag aacttcagct atgaccagag ggaaatgata   1380

ctaaatccag agggggatgt caactctgcc aaagtctgtg cccacataac aaatattcca   1440

ttcagcatta caaagatgga tgttcttcag ttcctagaag gaatcccagt ggatgaaaat   1500

gctgtacatg ttcttgttga taacaatggg caaggtctag gacaggcatt ggttcagttt   1560

aaaaatgaag atgatgcacg taagtctgaa cgcttacacc gtaaaaaact taatgggaga   1620

gaagcttttg ttcatgtagt taccctagaa gatatgagag agattgagaa aaatccccct   1680

gcccaaggaa aaaagggatt aaagatgcct gtgccaggta atcctgcagt tccaggaatg   1740

cccaatgcgg gactgcccgg tgtgggactg cccagtgcag gacttcccgg tgcaggcctg   1800

cccagcacag gactgcctgg ttcagcaata accagtgcag gactgcctgg tgcgggaatg   1860

cccagtgcag gaatacctag tgcaggaggt gaagagcatg ccttcctgac tgtaggatca   1920

aaggaagcca ataatgggcc tccatttaac tttcctggta attttggtgg atcaaatgcc   1980

tttgggccac caatccctcc tccaggatta ggaggcgggg cctttggtga tgctaggcct   2040

ggtatgcctt cagttggaaa cagtggtttg cctggtctag gactggatgt tccgggtttt   2100

ggaggtggac caaacaattt aagtgggcca tcgggatttg gagggggccc tcagaatttt   2160

ggaaatggcc ctggtagctt aggcggtccc ccggggtttg gaagtggccc tcctggtctt   2220

ggaagtgccc ctgggcattt gggtgggcca ccagcttttg ggcctggccc cggccccggc   2280

cccggccctg gcccaatcca tattggtggt ccccctggct ttgcatctag ttctggaaaa   2340

ccaggaccga cagtaattaa agtgcaaaac atgcccttta ctgtgtctat tgatgagatt   2400

ttagatttct tttatggcta tcaagtaatc ccaggctcag tgtgtttaaa atacaatgaa   2460

aaaggtatgc ccacaggtga agccatggtg gcctttgagt ctcgggatga agccacagct   2520

gctgtcattg acttaaatga caggcctata ggttcaagaa aagtaaaact tgtattaggg   2580

tagccattca catcattttt tatagggtag atcttcatat tgctgtgatt aatgcatcca   2640

gattgttttc ctagtatttc caggttagaa cctgtggatt gtttcaattg catatagctt   2700

ggtttccata acatagagca ttggttgact gtttacagaa gactcactca ccaggataaa   2760

cattgctgta tgttacagta aagctatctg gagagaacac ataaatgatt ttggcatacc   2820

attagagaaa ccatttgtaa aactcaaatg accacataaa gcttatcaag gagtctagat   2880

tggttttgtt ttataccata tgggatgaag aaaatagaaa tgtcagtaga actcattgag   2940

ggtgctcttg ccagctgctg aaaatagaag ttggctactc tcagaatttg gtttaaagct   3000

ggacagattt gctttgttat agggtaaagc tttgtctaaa gtcctcattt tcttttaaaa   3060

ttgaataaaa tttctgtata cagattcatt gtatgtacct ttattgcttc ttaagggtcc   3120

ttgctgtata gacagtcctg cttcagaagt tgctgctttg tttgtctaat tgactcattt   3180

gtaaatgagc agaactgttt tgttggtttt tttccctaaa tataaaagtc cacacttcgt   3240

ttgtgctata acctcaaact ttgatttcta atgtcacact taaaactgtg tggaataaga   3300

cttttgccat aaaaataaac tatggagtcc tttatctacc agagcctttt tggtttgacc   3360

gccacgattt aggttagtca gtttaaaaat tgttcatgtt gtttggatgg tatcgaaaac   3420

cagaaaccac ttttaataat gtgtttaaga tacttgattt gaagtccttt tcatatggac   3480

taattgtagt atcaatttcc tcctgtcccg attatgtgaa attttggcct ttaaacaaag   3540

aggggcccat tcataagaaa gtgttatatc taggttttta aaactgaagt tgaaattatc   3600

tttgttagca gtagtagtat agaataaaag atccgtatgc tggttcgtag attgatacgt   3660

gttagtcctg ttatttggag gctttttggc atagttgttc gatcaggagc ctgtttacta   3720

aaagtcttca tacagagtac aagtgcagcc gccagaggag aaaattgaga ttcttgaccc   3780

tttcatactc ttttctttgg tattcaggac actaaggcag gaggaccaca tgagttctgg   3840

ttggtaagtg tccttgtcat gaaaacactt gccttacaag gctctaatta tgatttccct   3900

agtcagtgct ctgaagatgt gtcacattat attataaaca atacggaagg ggagataggt   3960

gagatgatat gaaaaacaaa ttttctcact gtcataaaag gctctaatta tggttacttt   4020

ccttgtgatg aaaaacttgg ccttacaggg ctctagttat ggttactttc cctagtcaat   4080

gctctgaaaa tgtgtcacat tataaacaat acagaaggag agatagatga gagatcatga   4140

aaaccaaatt ttatctttta catggcccct ttgtcttcgt ttgaaacatc cccaacattt   4200

cctacaaatc agcgtagtta caaaggggtc agtcttttaa aataagtatt tcctattaaa   4260

ctatatatat atacagtgcc tttttggtgt tgtgagtcag tggaacactg aaatacagcg   4320

gttgtgtaat ttaagagtgg caacagtttc atttgataag atttgaaaag gctttttatc   4380

actacaatct tagaggattg acagtacagg atttttgttt aagagaagga ttgtttagac   4440

tcaagaggtg actatgttgt gggtcttttg ataattcatg aatacagatt tgctttgacc   4500

gatcactaga tactgcctcc tcaatttcaa aagcaatata acgtttgtat atgctgttta   4560

atttaagtta atgttaagta atcatttctc attccaaaga caatgcaaaa aacttcagca   4620

ctgcttgaga gttgtatttc agccacagat attttctcca ttggaaagct attttcattt   4680

tagaaaaatg ggttgtttga agatgaaagt cttttatctt ttttcacaat ttattttggt   4740

tatatgttcg tacattctta ttaaatattt catacacttt attgcaacta ctttgttatt   4800

tctacatctt agataaatgc tgaaaaggaa aacgatttca ttgttcatct aattaaataa   4860

attaaaagag cggtttgtgt agaaattgga gagaactatg ttttatatga atcacaacag   4920

tgctcgttgt ggactgtaat taaatgcttt gccctctgga acttgatttt tgtgtatctg   4980

agatttatta acagtgctaa ctgctaagga tactgtttat cttgttctgg gcattggagt   5040

ttcagttttt aaaaaattct tgaaaatgta ttctgtgaaa ctactcatac ctctcttcct   5100

gcgaattttc tcctaagaac taggtttggg gtagaaatga attgacatta ttttctcatt   5160

tgctttgtat ggtatgaagg atttgtaaag ctttgctcaa agttgtgtgc atttgtaaac   5220

actatcatga tattttcaat tttatgtgta aattttattg tctgtttttg gtgactctga   5280

cattaatgga agagaatatt ttccattaga tttaattttt tttcctctcc cttctgattt   5340

tttttttatt ggtgttcatt tttcttttga tttaaaggat tagagaaatc tacaaatgta   5400

tgtcataaat aagcaaattt gtaaactttt ctgaacttta gtgaaacatt tagttcacaa   5460

gcataatttg gaggtgtgtt ctgtgtttac acagtagttt ggatgtacaa ttattattag   5520

tggcttttta aaaaatgaaa cagtgttaag tgaaatgtag ttcctagctt tgtactccaa   5580

gttgtcaaag catcaacaat gaaaattcga ttaggaaact ttatttaaaa tttcaggtag   5640

taatattcag tgtagttaag gccagtctta acccactgga tgaaaatcta ggactgtatg   5700

gaagtaagca aacattacat ttttaggtgg aaatagtcag ccttgcataa aaacaaggat   5760

gcgtgaaagc cttaaattcc agctcccttt tactggagtc tgtggttgtg tacaggtatg   5820

ggccaagtgt aaaatctcat caattttaag aacactcggg aaatgagtaa agaaaatgta   5880

aaattgctgc tagtcaaatc ttttggaaag aatttctgga agtggtcact ttaaaaatta   5940

ttttccaccc ttgcaaaatt gccacattta aattgtttta ctggcagttc tatagtagtc   6000

cagactttag aaaccaaaca caacaaaatg gcttgttgcc aatatggcca caacattgcc   6060

agcaaatact gccttggcat cactcagcag aggtttttgt ttataaagat gaagtcttga   6120

atactgttca ataaacttgt c                                             6141


<210>  9726
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9726

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9727
<211>  6524
<212>  DNA
<213>  Homo sapiens

<400>  9727
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccggtgtg tgtggtttca gcgcagcatg gctgtggtca    180

tccgtttgca aggtctccca attgtggcgg ggaccatgga cattcgccac ttcttctctg    240

gattgaccat tcctgatggg ggcgtgcata ttgtaggggg tgaactgggt gaggctttca    300

tcgtttttgc cactgatgaa gatgcaaggc ttggtatgat gcgcacaggt ggtacaatta    360

aagggtcaaa agtaacacta ttgttgagta gtaagacgga aatgcagaat atgattgaac    420

tgagtcgtag gcgttttgaa actgccaact tagatatacc accagcaaat gccagtagat    480

caggaccacc acctagctca ggaatgagta gcagggtaaa cttgcccaca acagtatcca    540

actttaataa tccatcaccc agtgtagtta ctgccaccac ttctgttcat gaaagcaaca    600

aaaacataca gacattttcc acagccagcg taggaacagc tcctccaaat atgggggctt    660

cctttgggag cccaacgttt agctcaactg ttccaagcac agcctctcca atgaacacag    720

tcccgccgcc accaattcct ccaattccag cgatgccatc tctgccacca atgccatcca    780

ttcccccaat tccagttcct cctccagtac ctacattgcc tcctgtgcct cctgtgcccc    840

cgattccccc agttccttct gtgccaccca tgaccccact gccacccatg tcgggcatgc    900

cgcccttgaa tccgccacct gtggcacctc tacctgctgg aatgaatggc tctggagcac    960

ctatgaattt gaacaataat ctgaatccta tgtttcttgg tccgttgaat cctgttaacc   1020

ctatccagat gaactctcag agcagtgtga agccactccc catcaaccct gatgatctgt   1080

atgtcagtgt gcatggaatg cccttttctg caatggaaaa tgatgtcaga gatttttttc   1140

atgggctccg tgttgatgca gtgcatttgt tgaaagatca tgtaggtcga aataatggga   1200

atggattggt taagtttctc tcccctcaag atacatttga agctttgaaa cgaaacagaa   1260

tgctgatgat tcaacgctat gtggaagtta gccctgccac agaaagacag tgggtagctg   1320

ctggaggcca tatcactttt aagcaaaata tgggaccttc tggacaaact catccccctc   1380

ctcagacact tcccaggtca aaatcgccca gtgggcagaa aagatcaagg tcaagatcac   1440

cacatgaggc tggtttttgt gtttacttga aagggctacc atttgaagca gaaaacaaac   1500

atgtcattga tttttttaaa aagctggata ttgtggaaga tagtatttat atagcttatg   1560

gacccaatgg gaaagcaact ggcgaaggct ttgtagagtt cagaaatgag gctgactata   1620

aggctgctct gtgtcgtcat aaacagtaca tgggcaatcg ctttattcaa gttcatccaa   1680

ttactaagaa aggtatgcta gaaaagatag atatgattcg aaaaagactg cagaacttca   1740

gctatgacca gagggaaatg atactaaatc cagaggggga tgtcaactct gccaaagtct   1800

gtgcccacat aacaaatatt ccattcagca ttacaaagat ggatgttctt cagttcctag   1860

aaggaatccc agtggatgaa aatgctgtac atgttcttgt tgataacaat gggcaaggtc   1920

taggacaggc attggttcag tttaaaaatg aagatgatgc acgtaagtct gaacgcttac   1980

accgtaaaaa acttaatggg agagaagctt ttgttcatgt agttacccta gaagatatga   2040

gagagattga gaaaaatccc cctgcccaag gaaaaaaggg attaaagatg cctgtgccag   2100

gtaatcctgc agttccagga atgcccaatg cgggactgcc cggtgtggga ctgcccagtg   2160

caggacttcc cggtgcaggc ctgcccagca caggactgcc tggttcagca ataaccagtg   2220

caggactgcc tggtgcggga atgcccagtg caggaatacc tagtgcagga ggtgaagagc   2280

atgccttcct gactgtagga tcaaaggaag ccaataatgg gcctccattt aactttcctg   2340

gtaattttgg tggatcaaat gcctttgggc caccaatccc tcctccagga ttaggaggcg   2400

gggcctttgg tgatgctagg cctggtatgc cttcagttgg aaacagtggt ttgcctggtc   2460

taggactgga tgttccgggt tttggaggtg gaccaaacaa tttaagtggg ccatcgggat   2520

ttggaggggg ccctcagaat tttggaaatg gccctggtag cttaggcggt cccccggggt   2580

ttggaagtgg ccctcctggt cttggaagtg cccctgggca tttgggtggg ccaccagctt   2640

ttgggcctgg ccccggcccc ggccccggcc ctggcccaat ccatattggt ggtccccctg   2700

gctttgcatc tagttctgga aaaccaggac cgacagtaat taaagtgcaa aacatgccct   2760

ttactgtgtc tattgatgag attttagatt tcttttatgg ctatcaagta atcccaggct   2820

cagtgtgttt aaaatacaat gaaaaaggta tgcccacagg tgaagccatg gtggcctttg   2880

agtctcggga tgaagccaca gctgctgtca ttgacttaaa tgacaggcct ataggttcaa   2940

gaaaagtaaa acttgtatta gggtagccat tcacatcatt ttttataggg tagatcttca   3000

tattgctgtg attaatgcat ccagattgtt ttcctagtat ttccaggtta gaacctgtgg   3060

attgtttcaa ttgcatatag cttggtttcc ataacataga gcattggttg actgtttaca   3120

gaagactcac tcaccaggat aaacattgct gtatgttaca gtaaagctat ctggagagaa   3180

cacataaatg attttggcat accattagag aaaccatttg taaaactcaa atgaccacat   3240

aaagcttatc aaggagtcta gattggtttt gttttatacc atatgggatg aagaaaatag   3300

aaatgtcagt agaactcatt gagggtgctc ttgccagctg ctgaaaatag aagttggcta   3360

ctctcagaat ttggtttaaa gctggacaga tttgctttgt tatagggtaa agctttgtct   3420

aaagtcctca ttttctttta aaattgaata aaatttctgt atacagattc attgtatgta   3480

cctttattgc ttcttaaggg tccttgctgt atagacagtc ctgcttcaga agttgctgct   3540

ttgtttgtct aattgactca tttgtaaatg agcagaactg ttttgttggt ttttttccct   3600

aaatataaaa gtccacactt cgtttgtgct ataacctcaa actttgattt ctaatgtcac   3660

acttaaaact gtgtggaata agacttttgc cataaaaata aactatggag tcctttatct   3720

accagagcct ttttggtttg accgccacga tttaggttag tcagtttaaa aattgttcat   3780

gttgtttgga tggtatcgaa aaccagaaac cacttttaat aatgtgttta agatacttga   3840

tttgaagtcc ttttcatatg gactaattgt agtatcaatt tcctcctgtc ccgattatgt   3900

gaaattttgg cctttaaaca aagaggggcc cattcataag aaagtgttat atctaggttt   3960

ttaaaactga agttgaaatt atctttgtta gcagtagtag tatagaataa aagatccgta   4020

tgctggttcg tagattgata cgtgttagtc ctgttatttg gaggcttttt ggcatagttg   4080

ttcgatcagg agcctgttta ctaaaagtct tcatacagag tacaagtgca gccgccagag   4140

gagaaaattg agattcttga ccctttcata ctcttttctt tggtattcag gacactaagg   4200

caggaggacc acatgagttc tggttggtaa gtgtccttgt catgaaaaca cttgccttac   4260

aaggctctaa ttatgatttc cctagtcagt gctctgaaga tgtgtcacat tatattataa   4320

acaatacgga aggggagata ggtgagatga tatgaaaaac aaattttctc actgtcataa   4380

aaggctctaa ttatggttac tttccttgtg atgaaaaact tggccttaca gggctctagt   4440

tatggttact ttccctagtc aatgctctga aaatgtgtca cattataaac aatacagaag   4500

gagagataga tgagagatca tgaaaaccaa attttatctt ttacatggcc cctttgtctt   4560

cgtttgaaac atccccaaca tttcctacaa atcagcgtag ttacaaaggg gtcagtcttt   4620

taaaataagt atttcctatt aaactatata tatatacagt gcctttttgg tgttgtgagt   4680

cagtggaaca ctgaaataca gcggttgtgt aatttaagag tggcaacagt ttcatttgat   4740

aagatttgaa aaggcttttt atcactacaa tcttagagga ttgacagtac aggatttttg   4800

tttaagagaa ggattgttta gactcaagag gtgactatgt tgtgggtctt ttgataattc   4860

atgaatacag atttgctttg accgatcact agatactgcc tcctcaattt caaaagcaat   4920

ataacgtttg tatatgctgt ttaatttaag ttaatgttaa gtaatcattt ctcattccaa   4980

agacaatgca aaaaacttca gcactgcttg agagttgtat ttcagccaca gatattttct   5040

ccattggaaa gctattttca ttttagaaaa atgggttgtt tgaagatgaa agtcttttat   5100

cttttttcac aatttatttt ggttatatgt tcgtacattc ttattaaata tttcatacac   5160

tttattgcaa ctactttgtt atttctacat cttagataaa tgctgaaaag gaaaacgatt   5220

tcattgttca tctaattaaa taaattaaaa gagcggtttg tgtagaaatt ggagagaact   5280

atgttttata tgaatcacaa cagtgctcgt tgtggactgt aattaaatgc tttgccctct   5340

ggaacttgat ttttgtgtat ctgagattta ttaacagtgc taactgctaa ggatactgtt   5400

tatcttgttc tgggcattgg agtttcagtt tttaaaaaat tcttgaaaat gtattctgtg   5460

aaactactca tacctctctt cctgcgaatt ttctcctaag aactaggttt ggggtagaaa   5520

tgaattgaca ttattttctc atttgctttg tatggtatga aggatttgta aagctttgct   5580

caaagttgtg tgcatttgta aacactatca tgatattttc aattttatgt gtaaatttta   5640

ttgtctgttt ttggtgactc tgacattaat ggaagagaat attttccatt agatttaatt   5700

ttttttcctc tcccttctga tttttttttt attggtgttc atttttcttt tgatttaaag   5760

gattagagaa atctacaaat gtatgtcata aataagcaaa tttgtaaact tttctgaact   5820

ttagtgaaac atttagttca caagcataat ttggaggtgt gttctgtgtt tacacagtag   5880

tttggatgta caattattat tagtggcttt ttaaaaaatg aaacagtgtt aagtgaaatg   5940

tagttcctag ctttgtactc caagttgtca aagcatcaac aatgaaaatt cgattaggaa   6000

actttattta aaatttcagg tagtaatatt cagtgtagtt aaggccagtc ttaacccact   6060

ggatgaaaat ctaggactgt atggaagtaa gcaaacatta catttttagg tggaaatagt   6120

cagccttgca taaaaacaag gatgcgtgaa agccttaaat tccagctccc ttttactgga   6180

gtctgtggtt gtgtacaggt atgggccaag tgtaaaatct catcaatttt aagaacactc   6240

gggaaatgag taaagaaaat gtaaaattgc tgctagtcaa atcttttgga aagaatttct   6300

ggaagtggtc actttaaaaa ttattttcca cccttgcaaa attgccacat ttaaattgtt   6360

ttactggcag ttctatagta gtccagactt tagaaaccaa acacaacaaa atggcttgtt   6420

gccaatatgg ccacaacatt gccagcaaat actgccttgg catcactcag cagaggtttt   6480

tgtttataaa gatgaagtct tgaatactgt tcaataaact tgtc                    6524


<210>  9728
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9728

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9729
<211>  5786
<212>  DNA
<213>  Homo sapiens

<400>  9729
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccgtctaa aagttggttt taattggttg cccacaggat    180

tgacttggcc tctacctgct ggaatgaatg gctctggagc acctatgaat ttgaacaata    240

atctgaatcc tatgtttctt ggtccgttga atcctgttaa ccctatccag atgaactctc    300

agagcagtgt gaagccactc cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa    360

tgcccttttc tgcaatggaa aatgatgtca gagatttttt tcatgggctc cgtgttgatg    420

cagtgcattt gttgaaagat catgtaggtc gaaataatgg gaatggattg gttaagtttc    480

tctcccctca agatacattt gaagctttga aacgaaacag aatgctgatg attcaacgct    540

atgtggaagt tagccctgcc acagaaagac agtgggtagc tgctggaggc catatcactt    600

ttaagcaaaa tatgggacct tctggacaaa ctcatccccc tcctcagaca cttcccaggt    660

caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc accacatgag gctggttttt    720

gtgtttactt gaaagggcta ccatttgaag cagaaaacaa acatgtcatt gattttttta    780

aaaagctgga tattgtggaa gatagtattt atatagctta tggacccaat gggaaagcaa    840

ctggcgaagg ctttgtagag ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc    900

ataaacagta catgggcaat cgctttattc aagttcatcc aattactaag aaaggtatgc    960

tagaaaagat agatatgatt cgaaaaagac tgcagaactt cagctatgac cagagggaaa   1020

tgatactaaa tccagagggg gatgtcaact ctgccaaagt ctgtgcccac ataacaaata   1080

ttccattcag cattacaaag atggatgttc ttcagttcct agaaggaatc ccagtggatg   1140

aaaatgctgt acatgttctt gttgataaca atgggcaagg tctaggacag gcattggttc   1200

agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg   1260

ggagagaagc ttttgttcat gtagttaccc tagaagatat gagagagatt gagaaaaatc   1320

cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc aggtaatcct gcagttccag   1380

gaatgcccaa tgcgggactg cccggtgtgg gactgcccag tgcaggactt cccggtgcag   1440

gcctgcccag cacaggactg cctggttcag caataaccag tgcaggactg cctggtgcgg   1500

gaatgcccag tgcaggaata cctagtgcag gaggtgaaga gcatgccttc ctgactgtag   1560

gatcaaagga agccaataat gggcctccat ttaactttcc tggtaatttt ggtggatcaa   1620

atgcctttgg gccaccaatc cctcctccag gattaggagg cggggccttt ggtgatgcta   1680

ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg tctaggactg gatgttccgg   1740

gttttggagg tggaccaaac aatttaagtg ggccatcggg atttggaggg ggccctcaga   1800

attttggaaa tggccctggt agcttaggcg gtcccccggg gtttggaagt ggccctcctg   1860

gtcttggaag tgcccctggg catttgggtg ggccaccagc ttttgggcct ggccccggcc   1920

ccggccccgg ccctggccca atccatattg gtggtccccc tggctttgca tctagttctg   1980

gaaaaccagg accgacagta attaaagtgc aaaacatgcc ctttactgtg tctattgatg   2040

agattttaga tttcttttat ggctatcaag taatcccagg ctcagtgtgt ttaaaataca   2100

atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca   2160

cagctgctgt cattgactta aatgacaggc ctataggttc aagaaaagta aaacttgtat   2220

tagggtagcc attcacatca ttttttatag ggtagatctt catattgctg tgattaatgc   2280

atccagattg ttttcctagt atttccaggt tagaacctgt ggattgtttc aattgcatat   2340

agcttggttt ccataacata gagcattggt tgactgttta cagaagactc actcaccagg   2400

ataaacattg ctgtatgtta cagtaaagct atctggagag aacacataaa tgattttggc   2460

ataccattag agaaaccatt tgtaaaactc aaatgaccac ataaagctta tcaaggagtc   2520

tagattggtt ttgttttata ccatatggga tgaagaaaat agaaatgtca gtagaactca   2580

ttgagggtgc tcttgccagc tgctgaaaat agaagttggc tactctcaga atttggttta   2640

aagctggaca gatttgcttt gttatagggt aaagctttgt ctaaagtcct cattttcttt   2700

taaaattgaa taaaatttct gtatacagat tcattgtatg tacctttatt gcttcttaag   2760

ggtccttgct gtatagacag tcctgcttca gaagttgctg ctttgtttgt ctaattgact   2820

catttgtaaa tgagcagaac tgttttgttg gtttttttcc ctaaatataa aagtccacac   2880

ttcgtttgtg ctataacctc aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa   2940

taagactttt gccataaaaa taaactatgg agtcctttat ctaccagagc ctttttggtt   3000

tgaccgccac gatttaggtt agtcagttta aaaattgttc atgttgtttg gatggtatcg   3060

aaaaccagaa accactttta ataatgtgtt taagatactt gatttgaagt ccttttcata   3120

tggactaatt gtagtatcaa tttcctcctg tcccgattat gtgaaatttt ggcctttaaa   3180

caaagagggg cccattcata agaaagtgtt atatctaggt ttttaaaact gaagttgaaa   3240

ttatctttgt tagcagtagt agtatagaat aaaagatccg tatgctggtt cgtagattga   3300

tacgtgttag tcctgttatt tggaggcttt ttggcatagt tgttcgatca ggagcctgtt   3360

tactaaaagt cttcatacag agtacaagtg cagccgccag aggagaaaat tgagattctt   3420

gaccctttca tactcttttc tttggtattc aggacactaa ggcaggagga ccacatgagt   3480

tctggttggt aagtgtcctt gtcatgaaaa cacttgcctt acaaggctct aattatgatt   3540

tccctagtca gtgctctgaa gatgtgtcac attatattat aaacaatacg gaaggggaga   3600

taggtgagat gatatgaaaa acaaattttc tcactgtcat aaaaggctct aattatggtt   3660

actttccttg tgatgaaaaa cttggcctta cagggctcta gttatggtta ctttccctag   3720

tcaatgctct gaaaatgtgt cacattataa acaatacaga aggagagata gatgagagat   3780

catgaaaacc aaattttatc ttttacatgg cccctttgtc ttcgtttgaa acatccccaa   3840

catttcctac aaatcagcgt agttacaaag gggtcagtct tttaaaataa gtatttccta   3900

ttaaactata tatatataca gtgccttttt ggtgttgtga gtcagtggaa cactgaaata   3960

cagcggttgt gtaatttaag agtggcaaca gtttcatttg ataagatttg aaaaggcttt   4020

ttatcactac aatcttagag gattgacagt acaggatttt tgtttaagag aaggattgtt   4080

tagactcaag aggtgactat gttgtgggtc ttttgataat tcatgaatac agatttgctt   4140

tgaccgatca ctagatactg cctcctcaat ttcaaaagca atataacgtt tgtatatgct   4200

gtttaattta agttaatgtt aagtaatcat ttctcattcc aaagacaatg caaaaaactt   4260

cagcactgct tgagagttgt atttcagcca cagatatttt ctccattgga aagctatttt   4320

cattttagaa aaatgggttg tttgaagatg aaagtctttt atcttttttc acaatttatt   4380

ttggttatat gttcgtacat tcttattaaa tatttcatac actttattgc aactactttg   4440

ttatttctac atcttagata aatgctgaaa aggaaaacga tttcattgtt catctaatta   4500

aataaattaa aagagcggtt tgtgtagaaa ttggagagaa ctatgtttta tatgaatcac   4560

aacagtgctc gttgtggact gtaattaaat gctttgccct ctggaacttg atttttgtgt   4620

atctgagatt tattaacagt gctaactgct aaggatactg tttatcttgt tctgggcatt   4680

ggagtttcag tttttaaaaa attcttgaaa atgtattctg tgaaactact catacctctc   4740

ttcctgcgaa ttttctccta agaactaggt ttggggtaga aatgaattga cattattttc   4800

tcatttgctt tgtatggtat gaaggatttg taaagctttg ctcaaagttg tgtgcatttg   4860

taaacactat catgatattt tcaattttat gtgtaaattt tattgtctgt ttttggtgac   4920

tctgacatta atggaagaga atattttcca ttagatttaa ttttttttcc tctcccttct   4980

gatttttttt ttattggtgt tcatttttct tttgatttaa aggattagag aaatctacaa   5040

atgtatgtca taaataagca aatttgtaaa cttttctgaa ctttagtgaa acatttagtt   5100

cacaagcata atttggaggt gtgttctgtg tttacacagt agtttggatg tacaattatt   5160

attagtggct ttttaaaaaa tgaaacagtg ttaagtgaaa tgtagttcct agctttgtac   5220

tccaagttgt caaagcatca acaatgaaaa ttcgattagg aaactttatt taaaatttca   5280

ggtagtaata ttcagtgtag ttaaggccag tcttaaccca ctggatgaaa atctaggact   5340

gtatggaagt aagcaaacat tacattttta ggtggaaata gtcagccttg cataaaaaca   5400

aggatgcgtg aaagccttaa attccagctc ccttttactg gagtctgtgg ttgtgtacag   5460

gtatgggcca agtgtaaaat ctcatcaatt ttaagaacac tcgggaaatg agtaaagaaa   5520

atgtaaaatt gctgctagtc aaatcttttg gaaagaattt ctggaagtgg tcactttaaa   5580

aattattttc cacccttgca aaattgccac atttaaattg ttttactggc agttctatag   5640

tagtccagac tttagaaacc aaacacaaca aaatggcttg ttgccaatat ggccacaaca   5700

ttgccagcaa atactgcctt ggcatcactc agcagaggtt tttgtttata aagatgaagt   5760

cttgaatact gttcaataaa cttgtc                                        5786


<210>  9730
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  9730

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala 
        275                 280                 285


His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln 
    290                 295                 300


Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val 
305                 310                 315                 320


Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn 
                325                 330                 335


Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn 
            340                 345                 350


Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu 
        355                 360                 365


Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro 
    370                 375                 380


Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro 
385                 390                 395                 400


Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser 
                405                 410                 415


Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala 
            420                 425                 430


Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala 
        435                 440                 445


Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn 
    450                 455                 460


Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro 
465                 470                 475                 480


Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met 
                485                 490                 495


Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro 
            500                 505                 510


Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly 
        515                 520                 525


Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro 
    530                 535                 540


Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His 
545                 550                 555                 560


Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly 
                565                 570                 575


Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser 
            580                 585                 590


Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr 
        595                 600                 605


Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile 
    610                 615                 620


Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly 
625                 630                 635                 640


Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val 
                645                 650                 655


Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val 
            660                 665                 670


Leu Gly 



<210>  9731
<211>  5507
<212>  DNA
<213>  Homo sapiens

<400>  9731
ggaacgcgga gccgctgagc gggccgacgg ccattttgtg aagcggcgaa ggaggtggtg     60

gctgcgttgg gctccgggaa gccgttcggg ctggggctgt cggccgcggg gcggaggcac    120

tcgcgcgggg gtctaaaagt tggttttaat tggttgccca caggattgac ttggcctcta    180

cttcttgtta aggaaattca tctcttgttt tatcaggtgt gtgtggtttc agcgcagcat    240

ggctgtggtc atccgtttgc aaggtctccc aattgtggcg gggaccatgg acattcgcca    300

cttcttctct ggattgacca ttcctgatgg gggcgtgcat attgtagggg gtgaactggg    360

tgaggctttc atcgtttttg ccactgatga agatgcaagg cttggtatga tgcgcacagg    420

tggtacaatt aaagggtcaa aagtaacact attgttgagt agtaagacgg aaatgcagaa    480

tatgattgaa ctgatttttt aaaaagctgg atattgtgga agatagtatt tatatagctt    540

atggacccaa tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact    600

ataaggctgc tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc    660

caattactaa gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact    720

tcagctatga ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag    780

tctgtgccca cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc    840

tagaaggaat cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag    900

gtctaggaca ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct    960

tacaccgtaa aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata   1020

tgagagagat tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc   1080

caggtaatcc tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca   1140

gtgcaggact tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca   1200

gtgcaggact gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag   1260

agcatgcctt cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc   1320

ctggtaattt tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag   1380

gcggggcctt tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg   1440

gtctaggact ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg   1500

gatttggagg gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg   1560

ggtttggaag tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag   1620

cttttgggcc tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc   1680

ctggctttgc atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc   1740

cctttactgt gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag   1800

gctcagtgtg tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct   1860

ttgagtctcg ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt   1920

caagaaaagt aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct   1980

tcatattgct gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg   2040

tggattgttt caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt   2100

acagaagact cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga   2160

gaacacataa atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca   2220

cataaagctt atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa   2280

tagaaatgtc agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg   2340

ctactctcag aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg   2400

tctaaagtcc tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat   2460

gtacctttat tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct   2520

gctttgtttg tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc   2580

cctaaatata aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt   2640

cacacttaaa actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta   2700

tctaccagag cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt   2760

catgttgttt ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact   2820

tgatttgaag tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta   2880

tgtgaaattt tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg   2940

tttttaaaac tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc   3000

gtatgctggt tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag   3060

ttgttcgatc aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca   3120

gaggagaaaa ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta   3180

aggcaggagg accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct   3240

tacaaggctc taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta   3300

taaacaatac ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca   3360

taaaaggctc taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct   3420

agttatggtt actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag   3480

aaggagagat agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt   3540

cttcgtttga aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc   3600

ttttaaaata agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg   3660

agtcagtgga acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt   3720

gataagattt gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt   3780

ttgtttaaga gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa   3840

ttcatgaata cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc   3900

aatataacgt ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc   3960

caaagacaat gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt   4020

tctccattgg aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt   4080

tatctttttt cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata   4140

cactttattg caactacttt gttatttcta catcttagat aaatgctgaa aaggaaaacg   4200

atttcattgt tcatctaatt aaataaatta aaagagcggt ttgtgtagaa attggagaga   4260

actatgtttt atatgaatca caacagtgct cgttgtggac tgtaattaaa tgctttgccc   4320

tctggaactt gatttttgtg tatctgagat ttattaacag tgctaactgc taaggatact   4380

gtttatcttg ttctgggcat tggagtttca gtttttaaaa aattcttgaa aatgtattct   4440

gtgaaactac tcatacctct cttcctgcga attttctcct aagaactagg tttggggtag   4500

aaatgaattg acattatttt ctcatttgct ttgtatggta tgaaggattt gtaaagcttt   4560

gctcaaagtt gtgtgcattt gtaaacacta tcatgatatt ttcaatttta tgtgtaaatt   4620

ttattgtctg tttttggtga ctctgacatt aatggaagag aatattttcc attagattta   4680

attttttttc ctctcccttc tgattttttt tttattggtg ttcatttttc ttttgattta   4740

aaggattaga gaaatctaca aatgtatgtc ataaataagc aaatttgtaa acttttctga   4800

actttagtga aacatttagt tcacaagcat aatttggagg tgtgttctgt gtttacacag   4860

tagtttggat gtacaattat tattagtggc tttttaaaaa atgaaacagt gttaagtgaa   4920

atgtagttcc tagctttgta ctccaagttg tcaaagcatc aacaatgaaa attcgattag   4980

gaaactttat ttaaaatttc aggtagtaat attcagtgta gttaaggcca gtcttaaccc   5040

actggatgaa aatctaggac tgtatggaag taagcaaaca ttacattttt aggtggaaat   5100

agtcagcctt gcataaaaac aaggatgcgt gaaagcctta aattccagct cccttttact   5160

ggagtctgtg gttgtgtaca ggtatgggcc aagtgtaaaa tctcatcaat tttaagaaca   5220

ctcgggaaat gagtaaagaa aatgtaaaat tgctgctagt caaatctttt ggaaagaatt   5280

tctggaagtg gtcactttaa aaattatttt ccacccttgc aaaattgcca catttaaatt   5340

gttttactgg cagttctata gtagtccaga ctttagaaac caaacacaac aaaatggctt   5400

gttgccaata tggccacaac attgccagca aatactgcct tggcatcact cagcagaggt   5460

ttttgtttat aaagatgaag tcttgaatac tgttcaataa acttgtc                 5507


<210>  9732
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9732

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ile Phe 
                85


<210>  9733
<211>  6596
<212>  DNA
<213>  Homo sapiens

<400>  9733
tggaacgcgg agccgctgag cgggccgacg gccattttgt gaagcggcga aggaggtggt     60

ggctgcgttg ggctccggga agccgttcgg gctggggctg tcggccgcgg ggcggaggca    120

ctcgcgcggg ggtctaaaag ttggttttaa ttggttgccc acaggattga cttggcctct    180

acttcttgtt aaggaaattc atctcttgtt ttatcaggtg tgtgtggttt cagcgcagca    240

tggctgtggt catccgtttg caaggtctcc caattgtggc ggggaccatg gacattcgcc    300

acttcttctc tggattgacc attcctgatg ggggcgtgca tattgtaggg ggtgaactgg    360

gtgaggcttt catcgttttt gccactgatg aagatgcaag gcttggtatg atgcgcacag    420

gtggtacaat taaagggtca aaagtaacac tattgttgag tagtaagacg gaaatgcaga    480

atatgattga actgagtcgt aggcgttttg aaactgccaa cttagatata ccaccagcaa    540

atgccagtag atcaggacca ccacctagct caggaatgag tagcagggta aacttgccca    600

caacagtatc caactttaat aatccatcac ccagtgtagt tactgccacc acttctgttc    660

atgaaagcaa caaaaacata cagacatttt ccacagccag cgtaggaaca gctcctccaa    720

atatgggggc ttcctttggg agcccaacgt ttagctcaac tgttccaagc acagcctctc    780

caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca tctctgccac    840

caatgccatc cattccccca attccagttc ctcctccagt acctacattg cctcctgtgc    900

ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca ctgccaccca    960

tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg   1020

gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga   1080

atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc   1140

ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca   1200

gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc   1260

gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga   1320

aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac   1380

agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa   1440

ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa   1500

ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag   1560

cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt   1620

atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg   1680

aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc   1740

aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac   1800

tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact   1860

ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc   1920

ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca   1980

atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt   2040

ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc   2100

tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga   2160

tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg   2220

gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag   2280

caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag   2340

gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat   2400

ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag   2460

gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg   2520

gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg   2580

ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg   2640

gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg   2700

ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg   2760

gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc   2820

aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag   2880

taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca   2940

tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc   3000

ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag   3060

ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt   3120

tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt   3180

tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct   3240

atctggagag aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc   3300

aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga   3360

tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat   3420

agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt   3480

aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat   3540

tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca   3600

gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg   3660

gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat   3720

ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg   3780

agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt agtcagttta   3840

aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta ataatgtgtt   3900

taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa tttcctcctg   3960

tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata agaaagtgtt   4020

atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt agtatagaat   4080

aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt tggaggcttt   4140

ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag agtacaagtg   4200

cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc tttggtattc   4260

aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt gtcatgaaaa   4320

cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa gatgtgtcac   4380

attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa acaaattttc   4440

tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa cttggcctta   4500

cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt cacattataa   4560

acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc ttttacatgg   4620

cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt agttacaaag   4680

gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca gtgccttttt   4740

ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag agtggcaaca   4800

gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag gattgacagt   4860

acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat gttgtgggtc   4920

ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg cctcctcaat   4980

ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt aagtaatcat   5040

ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt atttcagcca   5100

cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg tttgaagatg   5160

aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat tcttattaaa   5220

tatttcatac actttattgc aactactttg ttatttctac atcttagata aatgctgaaa   5280

aggaaaacga tttcattgtt catctaatta aataaattaa aagagcggtt tgtgtagaaa   5340

ttggagagaa ctatgtttta tatgaatcac aacagtgctc gttgtggact gtaattaaat   5400

gctttgccct ctggaacttg atttttgtgt atctgagatt tattaacagt gctaactgct   5460

aaggatactg tttatcttgt tctgggcatt ggagtttcag tttttaaaaa attcttgaaa   5520

atgtattctg tgaaactact catacctctc ttcctgcgaa ttttctccta agaactaggt   5580

ttggggtaga aatgaattga cattattttc tcatttgctt tgtatggtat gaaggatttg   5640

taaagctttg ctcaaagttg tgtgcatttg taaacactat catgatattt tcaattttat   5700

gtgtaaattt tattgtctgt ttttggtgac tctgacatta atggaagaga atattttcca   5760

ttagatttaa ttttttttcc tctcccttct gatttttttt ttattggtgt tcatttttct   5820

tttgatttaa aggattagag aaatctacaa atgtatgtca taaataagca aatttgtaaa   5880

cttttctgaa ctttagtgaa acatttagtt cacaagcata atttggaggt gtgttctgtg   5940

tttacacagt agtttggatg tacaattatt attagtggct ttttaaaaaa tgaaacagtg   6000

ttaagtgaaa tgtagttcct agctttgtac tccaagttgt caaagcatca acaatgaaaa   6060

ttcgattagg aaactttatt taaaatttca ggtagtaata ttcagtgtag ttaaggccag   6120

tcttaaccca ctggatgaaa atctaggact gtatggaagt aagcaaacat tacattttta   6180

ggtggaaata gtcagccttg cataaaaaca aggatgcgtg aaagccttaa attccagctc   6240

ccttttactg gagtctgtgg ttgtgtacag gtatgggcca agtgtaaaat ctcatcaatt   6300

ttaagaacac tcgggaaatg agtaaagaaa atgtaaaatt gctgctagtc aaatcttttg   6360

gaaagaattt ctggaagtgg tcactttaaa aattattttc cacccttgca aaattgccac   6420

atttaaattg ttttactggc agttctatag tagtccagac tttagaaacc aaacacaaca   6480

aaatggcttg ttgccaatat ggccacaaca ttgccagcaa atactgcctt ggcatcactc   6540

agcagaggtt tttgtttata aagatgaagt cttgaatact gttcaataaa cttgtc       6596


<210>  9734
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9734

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9735
<211>  6642
<212>  DNA
<213>  Homo sapiens

<400>  9735
cttctggaac gcggagccgc tgagcgggcc gacggccatt ttgtgaagcg gcgaaggagg     60

tggtggctgc gttgggctcc gggaagccgt tcgggctggg gctgtcggcc gcggggcgga    120

ggcactcgcg cggggggtaa ttcggggtct gggttctggt gccgcgcagc tttccccgtc    180

taaaagttgg ttttaattgg ttgcccacag gattgacttg gcctctactt cttgttaagg    240

aaattcatct cttgttttat caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc    300

cgtttgcaag gtctcccaat tgtggcgggg accatggaca ttcgccactt cttctctgga    360

ttgaccattc ctgatggggg cgtgcatatt gtagggggtg aactgggtga ggctttcatc    420

gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa    480

gggtcaaaag taacactatt gttgagtagt aagacggaaa tgcagaatat gattgaactg    540

agtcgtaggc gttttgaaac tgccaactta gatataccac cagcaaatgc cagtagatca    600

ggaccaccac ctagctcagg aatgagtagc agggtaaact tgcccacaac agtatccaac    660

tttaataatc catcacccag tgtagttact gccaccactt ctgttcatga aagcaacaaa    720

aacatacaga cattttccac agccagcgta ggaacagctc ctccaaatat gggggcttcc    780

tttgggagcc caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc    840

ccgccgccac caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt    900

cccccaattc cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg    960

attcccccag ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg   1020

cccttgaatc cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct   1080

atgaatttga acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct   1140

atccagatga actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat   1200

gtcagtgtgc atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat   1260

gggctccgtg ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat   1320

ggattggtta agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg   1380

ctgatgattc aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct   1440

ggaggccata tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct   1500

cagacacttc ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca   1560

catgaggctg gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat   1620

gtcattgatt tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga   1680

cccaatggga aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag   1740

gctgctctgt gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt   1800

actaagaaag gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc   1860

tatgaccaga gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt   1920

gcccacataa caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa   1980

ggaatcccag tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta   2040

ggacaggcat tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac   2100

cgtaaaaaac ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga   2160

gagattgaga aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt   2220

aatcctgcag ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca   2280

ggacttcccg gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca   2340

ggactgcctg gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat   2400

gccttcctga ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt   2460

aattttggtg gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg   2520

gcctttggtg atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta   2580

ggactggatg ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt   2640

ggagggggcc ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt   2700

ggaagtggcc ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt   2760

gggcctggcc ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc   2820

tttgcatcta gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt   2880

actgtgtcta ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca   2940

gtgtgtttaa aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag   3000

tctcgggatg aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga   3060

aaagtaaaac ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata   3120

ttgctgtgat taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat   3180

tgtttcaatt gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga   3240

agactcactc accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca   3300

cataaatgat tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa   3360

agcttatcaa ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa   3420

atgtcagtag aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact   3480

ctcagaattt ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa   3540

agtcctcatt ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc   3600

tttattgctt cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt   3660

gtttgtctaa ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa   3720

atataaaagt ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac   3780

ttaaaactgt gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac   3840

cagagccttt ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt   3900

tgtttggatg gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt   3960

tgaagtcctt ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga   4020

aattttggcc tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt   4080

aaaactgaag ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg   4140

ctggttcgta gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt   4200

cgatcaggag cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga   4260

gaaaattgag attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca   4320

ggaggaccac atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa   4380

ggctctaatt atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac   4440

aatacggaag gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa   4500

ggctctaatt atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta   4560

tggttacttt ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga   4620

gagatagatg agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg   4680

tttgaaacat ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta   4740

aaataagtat ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca   4800

gtggaacact gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa   4860

gatttgaaaa ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt   4920

taagagaagg attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat   4980

gaatacagat ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat   5040

aacgtttgta tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag   5100

acaatgcaaa aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc   5160

attggaaagc tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct   5220

tttttcacaa tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt   5280

tattgcaact actttgttat ttctacatct tagataaatg ctgaaaagga aaacgatttc   5340

attgttcatc taattaaata aattaaaaga gcggtttgtg tagaaattgg agagaactat   5400

gttttatatg aatcacaaca gtgctcgttg tggactgtaa ttaaatgctt tgccctctgg   5460

aacttgattt ttgtgtatct gagatttatt aacagtgcta actgctaagg atactgttta   5520

tcttgttctg ggcattggag tttcagtttt taaaaaattc ttgaaaatgt attctgtgaa   5580

actactcata cctctcttcc tgcgaatttt ctcctaagaa ctaggtttgg ggtagaaatg   5640

aattgacatt attttctcat ttgctttgta tggtatgaag gatttgtaaa gctttgctca   5700

aagttgtgtg catttgtaaa cactatcatg atattttcaa ttttatgtgt aaattttatt   5760

gtctgttttt ggtgactctg acattaatgg aagagaatat tttccattag atttaatttt   5820

ttttcctctc ccttctgatt ttttttttat tggtgttcat ttttcttttg atttaaagga   5880

ttagagaaat ctacaaatgt atgtcataaa taagcaaatt tgtaaacttt tctgaacttt   5940

agtgaaacat ttagttcaca agcataattt ggaggtgtgt tctgtgttta cacagtagtt   6000

tggatgtaca attattatta gtggcttttt aaaaaatgaa acagtgttaa gtgaaatgta   6060

gttcctagct ttgtactcca agttgtcaaa gcatcaacaa tgaaaattcg attaggaaac   6120

tttatttaaa atttcaggta gtaatattca gtgtagttaa ggccagtctt aacccactgg   6180

atgaaaatct aggactgtat ggaagtaagc aaacattaca tttttaggtg gaaatagtca   6240

gccttgcata aaaacaagga tgcgtgaaag ccttaaattc cagctccctt ttactggagt   6300

ctgtggttgt gtacaggtat gggccaagtg taaaatctca tcaattttaa gaacactcgg   6360

gaaatgagta aagaaaatgt aaaattgctg ctagtcaaat cttttggaaa gaatttctgg   6420

aagtggtcac tttaaaaatt attttccacc cttgcaaaat tgccacattt aaattgtttt   6480

actggcagtt ctatagtagt ccagacttta gaaaccaaac acaacaaaat ggcttgttgc   6540

caatatggcc acaacattgc cagcaaatac tgccttggca tcactcagca gaggtttttg   6600

tttataaaga tgaagtcttg aatactgttc aataaacttg tc                      6642


<210>  9736
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9736

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9737
<211>  6510
<212>  DNA
<213>  Homo sapiens

<400>  9737
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggagga ttgacttggc ctctacttct tgttaaggaa attcatctct    120

tgttttatca ggtgtgtgtg gtttcagcgc agcatggctg tggtcatccg tttgcaaggt    180

ctcccaattg tggcggggac catggacatt cgccacttct tctctggatt gaccattcct    240

gatgggggcg tgcatattgt agggggtgaa ctgggtgagg ctttcatcgt ttttgccact    300

gatgaagatg caaggcttgg tatgatgcgc acaggtggta caattaaagg gtcaaaagta    360

acactattgt tgagtagtaa gacggaaatg cagaatatga ttgaactgag tcgtaggcgt    420

tttgaaactg ccaacttaga tataccacca gcaaatgcca gtagatcagg accaccacct    480

agctcaggaa tgagtagcag ggtaaacttg cccacaacag tatccaactt taataatcca    540

tcacccagtg tagttactgc caccacttct gttcatgaaa gcaacaaaaa catacagaca    600

ttttccacag ccagcgtagg aacagctcct ccaaatatgg gggcttcctt tgggagccca    660

acgtttagct caactgttcc aagcacagcc tctccaatga acacagtccc gccgccacca    720

attcctccaa ttccagcgat gccatctctg ccaccaatgc catccattcc cccaattcca    780

gttcctcctc cagtacctac attgcctcct gtgcctcctg tgcccccgat tcccccagtt    840

ccttctgtgc cacccatgac cccactgcca cccatgtcgg gcatgccgcc cttgaatccg    900

ccacctgtgg cacctctacc tgctggaatg aatggctctg gagcacctat gaatttgaac    960

aataatctga atcctatgtt tcttggtccg ttgaatcctg ttaaccctat ccagatgaac   1020

tctcagagca gtgtgaagcc actccccatc aaccctgatg atctgtatgt cagtgtgcat   1080

ggaatgccct tttctgcaat ggaaaatgat gtcagagatt tttttcatgg gctccgtgtt   1140

gatgcagtgc atttgttgaa agatcatgta ggtcgaaata atgggaatgg attggttaag   1200

tttctctccc ctcaagatac atttgaagct ttgaaacgaa acagaatgct gatgattcaa   1260

cgctatgtgg aagttagccc tgccacagaa agacagtggg tagctgctgg aggccatatc   1320

acttttaagc aaaatatggg accttctgga caaactcatc cccctcctca gacacttccc   1380

aggtcaaaat cgcccagtgg gcagaaaaga tcaaggtcaa gatcaccaca tgaggctggt   1440

ttttgtgttt acttgaaagg gctaccattt gaagcagaaa acaaacatgt cattgatttt   1500

tttaaaaagc tggatattgt ggaagatagt atttatatag cttatggacc caatgggaaa   1560

gcaactggcg aaggctttgt agagttcaga aatgaggctg actataaggc tgctctgtgt   1620

cgtcataaac agtacatggg caatcgcttt attcaagttc atccaattac taagaaaggt   1680

atgctagaaa agatagatat gattcgaaaa agactgcaga acttcagcta tgaccagagg   1740

gaaatgatac taaatccaga gggggatgtc aactctgcca aagtctgtgc ccacataaca   1800

aatattccat tcagcattac aaagatggat gttcttcagt tcctagaagg aatcccagtg   1860

gatgaaaatg ctgtacatgt tcttgttgat aacaatgggc aaggtctagg acaggcattg   1920

gttcagttta aaaatgaaga tgatgcacgt aagtctgaac gcttacaccg taaaaaactt   1980

aatgggagag aagcttttgt tcatgtagtt accctagaag atatgagaga gattgagaaa   2040

aatccccctg cccaaggaaa aaagggatta aagatgcctg tgccaggtaa tcctgcagtt   2100

ccaggaatgc ccaatgcggg actgcccggt gtgggactgc ccagtgcagg acttcccggt   2160

gcaggcctgc ccagcacagg actgcctggt tcagcaataa ccagtgcagg actgcctggt   2220

gcgggaatgc ccagtgcagg aatacctagt gcaggaggtg aagagcatgc cttcctgact   2280

gtaggatcaa aggaagccaa taatgggcct ccatttaact ttcctggtaa ttttggtgga   2340

tcaaatgcct ttgggccacc aatccctcct ccaggattag gaggcggggc ctttggtgat   2400

gctaggcctg gtatgccttc agttggaaac agtggtttgc ctggtctagg actggatgtt   2460

ccgggttttg gaggtggacc aaacaattta agtgggccat cgggatttgg agggggccct   2520

cagaattttg gaaatggccc tggtagctta ggcggtcccc cggggtttgg aagtggccct   2580

cctggtcttg gaagtgcccc tgggcatttg ggtgggccac cagcttttgg gcctggcccc   2640

ggccccggcc ccggccctgg cccaatccat attggtggtc cccctggctt tgcatctagt   2700

tctggaaaac caggaccgac agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt   2760

gatgagattt tagatttctt ttatggctat caagtaatcc caggctcagt gtgtttaaaa   2820

tacaatgaaa aaggtatgcc cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa   2880

gccacagctg ctgtcattga cttaaatgac aggcctatag gttcaagaaa agtaaaactt   2940

gtattagggt agccattcac atcatttttt atagggtaga tcttcatatt gctgtgatta   3000

atgcatccag attgttttcc tagtatttcc aggttagaac ctgtggattg tttcaattgc   3060

atatagcttg gtttccataa catagagcat tggttgactg tttacagaag actcactcac   3120

caggataaac attgctgtat gttacagtaa agctatctgg agagaacaca taaatgattt   3180

tggcatacca ttagagaaac catttgtaaa actcaaatga ccacataaag cttatcaagg   3240

agtctagatt ggttttgttt tataccatat gggatgaaga aaatagaaat gtcagtagaa   3300

ctcattgagg gtgctcttgc cagctgctga aaatagaagt tggctactct cagaatttgg   3360

tttaaagctg gacagatttg ctttgttata gggtaaagct ttgtctaaag tcctcatttt   3420

cttttaaaat tgaataaaat ttctgtatac agattcattg tatgtacctt tattgcttct   3480

taagggtcct tgctgtatag acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt   3540

gactcatttg taaatgagca gaactgtttt gttggttttt ttccctaaat ataaaagtcc   3600

acacttcgtt tgtgctataa cctcaaactt tgatttctaa tgtcacactt aaaactgtgt   3660

ggaataagac ttttgccata aaaataaact atggagtcct ttatctacca gagccttttt   3720

ggtttgaccg ccacgattta ggttagtcag tttaaaaatt gttcatgttg tttggatggt   3780

atcgaaaacc agaaaccact tttaataatg tgtttaagat acttgatttg aagtcctttt   3840

catatggact aattgtagta tcaatttcct cctgtcccga ttatgtgaaa ttttggcctt   3900

taaacaaaga ggggcccatt cataagaaag tgttatatct aggtttttaa aactgaagtt   3960

gaaattatct ttgttagcag tagtagtata gaataaaaga tccgtatgct ggttcgtaga   4020

ttgatacgtg ttagtcctgt tatttggagg ctttttggca tagttgttcg atcaggagcc   4080

tgtttactaa aagtcttcat acagagtaca agtgcagccg ccagaggaga aaattgagat   4140

tcttgaccct ttcatactct tttctttggt attcaggaca ctaaggcagg aggaccacat   4200

gagttctggt tggtaagtgt ccttgtcatg aaaacacttg ccttacaagg ctctaattat   4260

gatttcccta gtcagtgctc tgaagatgtg tcacattata ttataaacaa tacggaaggg   4320

gagataggtg agatgatatg aaaaacaaat tttctcactg tcataaaagg ctctaattat   4380

ggttactttc cttgtgatga aaaacttggc cttacagggc tctagttatg gttactttcc   4440

ctagtcaatg ctctgaaaat gtgtcacatt ataaacaata cagaaggaga gatagatgag   4500

agatcatgaa aaccaaattt tatcttttac atggcccctt tgtcttcgtt tgaaacatcc   4560

ccaacatttc ctacaaatca gcgtagttac aaaggggtca gtcttttaaa ataagtattt   4620

cctattaaac tatatatata tacagtgcct ttttggtgtt gtgagtcagt ggaacactga   4680

aatacagcgg ttgtgtaatt taagagtggc aacagtttca tttgataaga tttgaaaagg   4740

ctttttatca ctacaatctt agaggattga cagtacagga tttttgttta agagaaggat   4800

tgtttagact caagaggtga ctatgttgtg ggtcttttga taattcatga atacagattt   4860

gctttgaccg atcactagat actgcctcct caatttcaaa agcaatataa cgtttgtata   4920

tgctgtttaa tttaagttaa tgttaagtaa tcatttctca ttccaaagac aatgcaaaaa   4980

acttcagcac tgcttgagag ttgtatttca gccacagata ttttctccat tggaaagcta   5040

ttttcatttt agaaaaatgg gttgtttgaa gatgaaagtc ttttatcttt tttcacaatt   5100

tattttggtt atatgttcgt acattcttat taaatatttc atacacttta ttgcaactac   5160

tttgttattt ctacatctta gataaatgct gaaaaggaaa acgatttcat tgttcatcta   5220

attaaataaa ttaaaagagc ggtttgtgta gaaattggag agaactatgt tttatatgaa   5280

tcacaacagt gctcgttgtg gactgtaatt aaatgctttg ccctctggaa cttgattttt   5340

gtgtatctga gatttattaa cagtgctaac tgctaaggat actgtttatc ttgttctggg   5400

cattggagtt tcagttttta aaaaattctt gaaaatgtat tctgtgaaac tactcatacc   5460

tctcttcctg cgaattttct cctaagaact aggtttgggg tagaaatgaa ttgacattat   5520

tttctcattt gctttgtatg gtatgaagga tttgtaaagc tttgctcaaa gttgtgtgca   5580

tttgtaaaca ctatcatgat attttcaatt ttatgtgtaa attttattgt ctgtttttgg   5640

tgactctgac attaatggaa gagaatattt tccattagat ttaatttttt ttcctctccc   5700

ttctgatttt ttttttattg gtgttcattt ttcttttgat ttaaaggatt agagaaatct   5760

acaaatgtat gtcataaata agcaaatttg taaacttttc tgaactttag tgaaacattt   5820

agttcacaag cataatttgg aggtgtgttc tgtgtttaca cagtagtttg gatgtacaat   5880

tattattagt ggctttttaa aaaatgaaac agtgttaagt gaaatgtagt tcctagcttt   5940

gtactccaag ttgtcaaagc atcaacaatg aaaattcgat taggaaactt tatttaaaat   6000

ttcaggtagt aatattcagt gtagttaagg ccagtcttaa cccactggat gaaaatctag   6060

gactgtatgg aagtaagcaa acattacatt tttaggtgga aatagtcagc cttgcataaa   6120

aacaaggatg cgtgaaagcc ttaaattcca gctccctttt actggagtct gtggttgtgt   6180

acaggtatgg gccaagtgta aaatctcatc aattttaaga acactcggga aatgagtaaa   6240

gaaaatgtaa aattgctgct agtcaaatct tttggaaaga atttctggaa gtggtcactt   6300

taaaaattat tttccaccct tgcaaaattg ccacatttaa attgttttac tggcagttct   6360

atagtagtcc agactttaga aaccaaacac aacaaaatgg cttgttgcca atatggccac   6420

aacattgcca gcaaatactg ccttggcatc actcagcaga ggtttttgtt tataaagatg   6480

aagtcttgaa tactgttcaa taaacttgtc                                    6510


<210>  9738
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9738

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9739
<211>  5192
<212>  DNA
<213>  Homo sapiens

<400>  9739
gaaatgcctc cgaggtccat tgctggggag gggctttact cgagggtgta gcagttttga     60

gaagccggcg tctgaagcta ggagtctaaa agttggtttt aattggttgc ccacaggatt    120

gacttggcct ctacttcttg ttaaggaaat tcatctcttg ttttatcagg tgtgtgtggt    180

ttcagcgcag catggctgtg gtcatccgtt tgcaaggtct cccaattgtg gcggggacca    240

tggacattcg ccacttcttc tctggattga ccattcctga tgggggcgtg catattgtag    300

ggggtgaact gggtgaggct ttcatcgttt ttgccactga tgaagatgca aggcttggta    360

tgatgcgcac aggtggtaca attaaagggt caaaagtaac actattgttg agtagtaaga    420

cggaaatgca gaatatgatt gaactgagtc gtaggcgttt tgaaactgcc aacttagata    480

taccaccagc aaatgccagt agatcaggac caccacctag ctcaggaatg agtagcaggg    540

taaacttgcc cacaacagta tccaacttta ataatccatc acccagtgta gttactgcca    600

ccacttctgt tcatgaaagc aacaaaaaca tacagacatt ttccacagcc agcgtaggaa    660

cagctcctcc aaatatgggg gcttcctttg ggagcccaac gtttagctca actgttccaa    720

gcacagcctc tccaatgaac acagtcccgc cgccaccaat tcctccaatt ccagcgatgc    780

catctctgcc accaatgcca tccattcccc caattccagt tcctcctcca gtacctacat    840

tgcctcctgt gcctcctgtg cccccgattc ccccagttcc ttctgtgcca cccatgaccc    900

cactgccacc catgtcgggc atgccgccct tgaatccgcc acctgtggca cctctacctg    960

ctggaatgaa tggctctgga gcacctatga atttgaacaa taatctgaat cctatgtttc   1020

ttggtccgtt gaatcctgtt aaccctatcc agatgaactc tcagagcagt gtgaagccac   1080

tccccatcaa ccctgatgat ctgtatgtca gtgtgcatgg aatgcccttt tctgcaatgg   1140

aaaatgatgt cagagatttt tttcatgggc tccgtgttga tgcagtgcat ttgttgaaag   1200

atcatgtagg tcgaaataat gggaatggat tggttaagtt tctctcccct caagatacat   1260

ttgaagcttt gaaacgaaac agaatgctga tgattcaacg ctatgtggaa gttagccctg   1320

ccacagaaag acagtgggta gctgctggag gccatatcac ttttaagcaa aatatgggac   1380

cttctggaca aactcatccc cctcctcaga cacttcccag gtcaaaatcg cccagtgggc   1440

agaaaagatc aaggtcaaga tcaccacatg aggctggttt ttgtgtttac ttgaaagggc   1500

taccatttga agcagaaaac aaacatgtca ttgatttttt taaaaagctg gatattgtgg   1560

aagatagtat ttatatagct tatggaccca atgggaaagc aactggcgaa ggctttgtag   1620

agttcagaaa tgaggctgac tataaggctg ctctgtgtcg tcataaacag tacatgggca   1680

atcgctttat tcaagttcat ccaattacta agaaaggtat gctagaaaag atagatatga   1740

ttcgaaaaag actgcagaac ttcagctatg accagaggga aatgatacta aatccagagg   1800

gggatgtcaa ctctgccaaa gtctgtgccc acataacaaa tattccattc agcattacaa   1860

agatggatgt tcttcagttc ctagaaggaa tcccagtgga tgaaaatgct gtacatgttc   1920

ttgttgataa caatgggcaa ggtctaggac aggcattggt tcagtttaaa aatgaagatg   1980

atgcacgtaa gtctgaacgc ttacaccgta aaaaacttaa tgggagagaa gcttttgttc   2040

atgtagttac cctagaagat atgagagaga ttgagaaaaa tccccctgcc caaggaaaaa   2100

agggattaaa gatgcctgtg ccaggtaatc ctgcagttcc aggaatgccc aatgcgggac   2160

tgcccggtgt gggactgccc agtgcaggac ttcccggtgc aggcctgccc agcacaggac   2220

tgcctggttc agcaataacc agtgcaggac tgcctggtgc gggaatgccc agtgcaggaa   2280

tacctagtgc aggaggtgaa gagcatgcct tcctgactgt aggatcaaag gaagccaata   2340

atgggcctcc atttaacttt cctggtaatt ttggtggatc aaatgccttt gggccaccaa   2400

tccctcctcc aggattagga ggcggggcct ttggtgatgc taggcctggt atgccttcag   2460

ttggaaacag tggtttgcct ggtctaggac tggatgttcc gggttttgga ggtggaccaa   2520

acaatttaag tgggccatcg ggatttggag ggggccctca gaattttgga aatggccctg   2580

gtagcttagg cggtcccccg gggtttggaa gtggccctcc tggtcttgga agtgcccctg   2640

ggcatttggg tgggccacca gcttttgggc ctggccccgg ccccggcccc ggccctggcc   2700

caatccatat tggtggtccc cctggctttg catctagttc tggaaaacca ggaccgacag   2760

taattaaagt gcaaaacatg ccctttactg tgtctattga tgagatttta gatttctttt   2820

atggctatca agtaatccca ggctcagtgt gtttaaaata caatgaaaaa ggtatgccca   2880

caggtgaagc catggtggcc tttgagtctc gggatgaagc cacagctgct gtcattgact   2940

taaatgacag gcctataggt tcaagaaaag taaaacttgt attagggtag ccattcacat   3000

cattttttat agggtagatc ttcatattgc tgtgattaat gcatccagat tgttttccta   3060

gtatttccag gttagaacct gtggattgtt tcaattgcat atagcttggt ttccataaca   3120

tagagcattg gttgactgtt tacagaagac tcactcacca ggataaacat tgctgtatgt   3180

tacagtaaag ctatctggag agaacacata aatgattttg gcataccatt agagaaacca   3240

tttgtaaaac tcaaatgacc acataaagct tatcaaggag tctagattgg ttttgtttta   3300

taccatatgg gatgaagaaa atagaaatgt cagtagaact cattgagggt gctcttgcca   3360

gctgctgaaa atagaagttg gctactctca gaatttggtt taaagctgga cagatttgct   3420

ttgttatagg gtaaagcttt gtctaaagtc ctcattttct tttaaaattg aataaaattt   3480

ctgtatacag attcattgta tgtaccttta ttgcttctta agggtccttg ctgtatagac   3540

agtcctgctt cagaagttgc tgctttgttt gtctaattga ctcatttgta aatgagcaga   3600

actgttttgt tggttttttt ccctaaatat aaaagtccac acttcgtttg tgctataacc   3660

tcaaactttg atttctaatg tcacacttaa aactgtgtgg aataagactt ttgccataaa   3720

aataaactat ggagtccttt atctaccaga gcctttttgg tttgaccgcc acgatttagg   3780

ttagtcagtt taaaaattgt tcatgttgtt tggatggtat cgaaaaccag aaaccacttt   3840

taataatgtg tttaagatac ttgatttgaa gtccttttca tatggactaa ttgtagtatc   3900

aatttcctcc tgtcccgatt atgtgaaatt ttggccttta aacaaagagg ggcccattca   3960

taagaaagtg ttatatctag gtttttaaaa ctgaagttga aattatcttt gttagcagta   4020

gtagtataga ataaaagatc cgtatgctgg ttcgtagatt gatacgtgtt agtcctgtta   4080

tttggaggct ttttggcata gttgttcgat caggagcctg tttactaaaa gtcttcatac   4140

agagtacaag tgcagccgcc agaggagaaa attgagattc ttgacccttt catactcttt   4200

tctttggtat tcaggacact aaggcaggag gaccacatga gttctggttg gtaagtgtcc   4260

ttgtcatgaa aacacttgcc ttacaaggct ctaattatga tttccctagt cagtgctctg   4320

aagatgtgtc acattatatt ataaacaata cggaagggga gataggtgag atgatatgaa   4380

aaacaaattt tctcactgtc ataaaaggct ctaattatgg ttactttcct tgtgatgaaa   4440

aacttggcct tacagggctc tagttatggt tactttccct agtcaatgct ctgaaaatgt   4500

gtcacattat aaacaataca gaaggagaga tagatgagag atcatgaaaa ccaaatttta   4560

tcttttacat ggcccctttg tcttcgtttg aaacatcccc aacatttcct acaaatcagc   4620

gtagttacaa aggggtcagt cttttaaaat aagtatttcc tattaaacta tatatatata   4680

cagtgccttt ttggtgttgt gagtcagtgg aacactgaaa tacagcggtt gtgtaattta   4740

agagtggcaa cagtttcatt tgataagatt tgaaaaggct ttttatcact acaatcttag   4800

aggattgaca gtacaggatt tttgtttaag agaaggattg tttagactca agaggtgact   4860

atgttgtggg tcttttgata attcatgaat acagatttgc tttgaccgat cactagatac   4920

tgcctcctca atttcaaaag caatataacg tttgtatatg ctgtttaatt taagttaatg   4980

ttaagtaatc atttctcatt ccaaagacaa tgcaaaaaac ttcagcactg cttgagagtt   5040

gtatttcagc cacagatatt ttctccattg gaaagctatt ttcattttag aaaaatgggt   5100

tgtttgaaga tgaaagtctt ttatcttttt tcacaattta ttttggttat atgttcgtac   5160

attcttatta aatatttcat acactttatt gc                                 5192


<210>  9740
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9740

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9741
<211>  4676
<212>  DNA
<213>  Homo sapiens

<400>  9741
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc    180

caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac    240

caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt cccccaattc    300

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    360

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    420

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    480

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    540

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    600

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    660

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    720

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    780

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    840

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    900

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    960

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt   1020

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1080

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1140

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1200

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1260

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1320

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1380

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1440

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1500

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1560

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1620

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1680

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1740

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1800

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1860

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1920

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1980

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   2040

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2100

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2160

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2220

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2280

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2340

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2400

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2460

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2520

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2580

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2640

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2700

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2760

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2820

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2880

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2940

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   3000

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3060

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3120

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3180

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3240

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3300

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3360

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3420

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3480

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3540

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3600

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3660

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3720

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3780

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3840

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3900

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3960

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   4020

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4080

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4140

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4200

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4260

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4320

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4380

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4440

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4500

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4560

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4620

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgc       4676


<210>  9742
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9742

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9743
<211>  4710
<212>  DNA
<213>  Homo sapiens

<400>  9743
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg tgttccaagc    240

acagcctctc caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca    300

tctctgccac caatgccatc cattccccca attccagttc ctcctccagt acctacattg    360

cctcctgtgc ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca    420

ctgccaccca tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct    480

ggaatgaatg gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt    540

ggtccgttga atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc    600

cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa    660

aatgatgtca gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat    720

catgtaggtc gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt    780

gaagctttga aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc    840

acagaaagac agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct    900

tctggacaaa ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag    960

aaaagatcaa ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta   1020

ccatttgaag cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa   1080

gatagtattt atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag   1140

ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat   1200

cgctttattc aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt   1260

cgaaaaagac tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg   1320

gatgtcaact ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag   1380

atggatgttc ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt   1440

gttgataaca atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat   1500

gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat   1560

gtagttaccc tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag   1620

ggattaaaga tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg   1680

cccggtgtgg gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg   1740

cctggttcag caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata   1800

cctagtgcag gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat   1860

gggcctccat ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc   1920

cctcctccag gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt   1980

ggaaacagtg gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac   2040

aatttaagtg ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt   2100

agcttaggcg gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg   2160

catttgggtg ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca   2220

atccatattg gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta   2280

attaaagtgc aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat   2340

ggctatcaag taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca   2400

ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta   2460

aatgacaggc ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca   2520

ttttttatag ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt   2580

atttccaggt tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata   2640

gagcattggt tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta   2700

cagtaaagct atctggagag aacacataaa tgattttggc ataccattag agaaaccatt   2760

tgtaaaactc aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata   2820

ccatatggga tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc   2880

tgctgaaaat agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt   2940

gttatagggt aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct   3000

gtatacagat tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag   3060

tcctgcttca gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac   3120

tgttttgttg gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc   3180

aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa   3240

taaactatgg agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt   3300

agtcagttta aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta   3360

ataatgtgtt taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa   3420

tttcctcctg tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata   3480

agaaagtgtt atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt   3540

agtatagaat aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt   3600

tggaggcttt ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag   3660

agtacaagtg cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc   3720

tttggtattc aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt   3780

gtcatgaaaa cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa   3840

gatgtgtcac attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa   3900

acaaattttc tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa   3960

cttggcctta cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt   4020

cacattataa acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc   4080

ttttacatgg cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt   4140

agttacaaag gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca   4200

gtgccttttt ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag   4260

agtggcaaca gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag   4320

gattgacagt acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat   4380

gttgtgggtc ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg   4440

cctcctcaat ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt   4500

aagtaatcat ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt   4560

atttcagcca cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg   4620

tttgaagatg aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat   4680

tcttattaaa tatttcatac actttattgc                                    4710


<210>  9744
<211>  751
<212>  PRT
<213>  Homo sapiens

<400>  9744

Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro 
1               5                   10                  15


Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro 
            20                  25                  30


Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val 
        35                  40                  45


Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro 
    50                  55                  60


Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly 
65                  70                  75                  80


Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu 
                85                  90                  95


Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser 
            100                 105                 110


Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His 
        115                 120                 125


Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His 
    130                 135                 140


Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg 
145                 150                 155                 160


Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe 
                165                 170                 175


Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu 
            180                 185                 190


Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile 
        195                 200                 205


Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro 
    210                 215                 220


Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg 
225                 230                 235                 240


Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu 
                245                 250                 255


Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu 
            260                 265                 270


Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys 
        275                 280                 285


Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys 
    290                 295                 300


Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln 
305                 310                 315                 320


Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile 
                325                 330                 335


Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu 
            340                 345                 350


Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr 
        355                 360                 365


Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu 
    370                 375                 380


Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn 
385                 390                 395                 400


Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp 
                405                 410                 415


Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu 
            420                 425                 430


Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys 
        435                 440                 445


Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly 
    450                 455                 460


Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly 
465                 470                 475                 480


Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu 
                485                 490                 495


Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro 
            500                 505                 510


Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr 
        515                 520                 525


Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly 
    530                 535                 540


Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly 
545                 550                 555                 560


Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val 
                565                 570                 575


Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly 
            580                 585                 590


Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro 
        595                 600                 605


Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe 
    610                 615                 620


Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly 
625                 630                 635                 640


Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
                645                 650                 655


Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro 
            660                 665                 670


Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile 
        675                 680                 685


Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser 
    690                 695                 700


Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met 
705                 710                 715                 720


Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu 
                725                 730                 735


Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
            740                 745                 750


<210>  9745
<211>  4616
<212>  DNA
<213>  Homo sapiens

<400>  9745
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatcttc tgccaccaat gccatccatt cccccaattc    240

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    300

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    360

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    420

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    480

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    540

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    600

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    660

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    720

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    780

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    840

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    900

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt    960

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1020

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1080

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1140

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1200

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1260

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1320

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1380

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1440

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1500

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1560

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1620

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1680

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1740

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1800

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1860

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1920

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   1980

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2040

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2100

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2160

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2220

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2280

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2340

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2400

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2460

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2520

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2580

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2640

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2700

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2760

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2820

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2880

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   2940

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3000

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3060

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3120

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac cagagccttt   3180

ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt tgtttggatg   3240

gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt tgaagtcctt   3300

ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga aattttggcc   3360

tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt aaaactgaag   3420

ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg ctggttcgta   3480

gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt cgatcaggag   3540

cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga gaaaattgag   3600

attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca ggaggaccac   3660

atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa ggctctaatt   3720

atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac aatacggaag   3780

gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa ggctctaatt   3840

atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta tggttacttt   3900

ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga gagatagatg   3960

agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg tttgaaacat   4020

ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta aaataagtat   4080

ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca gtggaacact   4140

gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa gatttgaaaa   4200

ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt taagagaagg   4260

attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat gaatacagat   4320

ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat aacgtttgta   4380

tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag acaatgcaaa   4440

aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc attggaaagc   4500

tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct tttttcacaa   4560

tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt tattgc       4616


<210>  9746
<211>  731
<212>  PRT
<213>  Homo sapiens

<400>  9746

Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr Leu 
1               5                   10                  15


Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val Pro 
            20                  25                  30


Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro 
        35                  40                  45


Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro 
    50                  55                  60


Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn 
65                  70                  75                  80


Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu 
                85                  90                  95


Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe 
            100                 105                 110


Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val 
        115                 120                 125


Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn 
    130                 135                 140


Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys 
145                 150                 155                 160


Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala 
                165                 170                 175


Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln 
            180                 185                 190


Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro 
        195                 200                 205


Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro 
    210                 215                 220


His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala 
225                 230                 235                 240


Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu 
                245                 250                 255


Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu 
            260                 265                 270


Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys 
        275                 280                 285


Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile 
    290                 295                 300


Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu 
305                 310                 315                 320


Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly 
                325                 330                 335


Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe 
            340                 345                 350


Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val 
        355                 360                 365


Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu 
    370                 375                 380


Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys Ser 
385                 390                 395                 400


Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val His 
                405                 410                 415


Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro Ala 
            420                 425                 430


Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala Val 
        435                 440                 445


Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser Ala 
    450                 455                 460


Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser Ala 
465                 470                 475                 480


Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly Ile 
                485                 490                 495


Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser Lys 
            500                 505                 510


Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly Gly 
        515                 520                 525


Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly Gly 
    530                 535                 540


Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser Gly 
545                 550                 555                 560


Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro Asn 
                565                 570                 575


Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe Gly 
            580                 585                 590


Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly Pro 
        595                 600                 605


Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala Phe 
    610                 615                 620


Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile Gly 
625                 630                 635                 640


Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr Val 
                645                 650                 655


Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile Leu 
            660                 665                 670


Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu Lys 
        675                 680                 685


Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe Glu 
    690                 695                 700


Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg Pro 
705                 710                 715                 720


Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
                725                 730


<210>  9747
<211>  5101
<212>  DNA
<213>  Homo sapiens

<400>  9747
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

cattcctgat gggggcgtgc atattgtagg gggtgaactg ggtgaggctt tcatcgtttt    240

tgccactgat gaagatgcaa ggcttggtat gatgcgcaca ggtggtacaa ttaaagggtc    300

aaaagtaaca ctattgttga gtagtaagac ggaaatgcag aatatgattg aactgagtcg    360

taggcgtttt gaaactgcca acttagatat accaccagca aatgccagta gatcaggacc    420

accacctagc tcaggaatga gtagcagggt aaacttgccc acaacagtat ccaactttaa    480

taatccatca cccagtgtag ttactgccac cacttctgtt catgaaagca acaaaaacat    540

acagacattt tccacagcca gcgtaggaac agctcctcca aatatggggg cttcctttgg    600

gagcccaacg tttagctcaa ctgttccaag cacagcctct ccaatgaaca cagtcccgcc    660

gccaccaatt cctccaattc cagcgatgcc atctctgcca ccaatgccat ccattccccc    720

aattccagtt cctcctccag tacctacatt gcctcctgtg cctcctgtgc ccccgattcc    780

cccagttcct tctgtgccac ccatgacccc actgccaccc atgtcgggca tgccgccctt    840

gaatccgcca cctgtggcac ctctacctgc tggaatgaat ggctctggag cacctatgaa    900

tttgaacaat aatctgaatc ctatgtttct tggtccgttg aatcctgtta accctatcca    960

gatgaactct cagagcagtg tgaagccact ccccatcaac cctgatgatc tgtatgtcag   1020

tgtgcatgga atgccctttt ctgcaatgga aaatgatgtc agagattttt ttcatgggct   1080

ccgtgttgat gcagtgcatt tgttgaaaga tcatgtaggt cgaaataatg ggaatggatt   1140

ggttaagttt ctctcccctc aagatacatt tgaagctttg aaacgaaaca gaatgctgat   1200

gattcaacgc tatgtggaag ttagccctgc cacagaaaga cagtgggtag ctgctggagg   1260

ccatatcact tttaagcaaa atatgggacc ttctggacaa actcatcccc ctcctcagac   1320

acttcccagg tcaaaatcgc ccagtgggca gaaaagatca aggtcaagat caccacatga   1380

ggctggtttt tgtgtttact tgaaagggct accatttgaa gcagaaaaca aacatgtcat   1440

tgattttttt aaaaagctgg atattgtgga agatagtatt tatatagctt atggacccaa   1500

tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact ataaggctgc   1560

tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc caattactaa   1620

gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact tcagctatga   1680

ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag tctgtgccca   1740

cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc tagaaggaat   1800

cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag gtctaggaca   1860

ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct tacaccgtaa   1920

aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata tgagagagat   1980

tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc caggtaatcc   2040

tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca gtgcaggact   2100

tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca gtgcaggact   2160

gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag agcatgcctt   2220

cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc ctggtaattt   2280

tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag gcggggcctt   2340

tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg gtctaggact   2400

ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg gatttggagg   2460

gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg ggtttggaag   2520

tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag cttttgggcc   2580

tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc ctggctttgc   2640

atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc cctttactgt   2700

gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag gctcagtgtg   2760

tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct ttgagtctcg   2820

ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt caagaaaagt   2880

aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct tcatattgct   2940

gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg tggattgttt   3000

caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt acagaagact   3060

cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga gaacacataa   3120

atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca cataaagctt   3180

atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa tagaaatgtc   3240

agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg ctactctcag   3300

aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg tctaaagtcc   3360

tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat gtacctttat   3420

tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct gctttgtttg   3480

tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc cctaaatata   3540

aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt cacacttaaa   3600

actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta tctaccagag   3660

cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt catgttgttt   3720

ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact tgatttgaag   3780

tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta tgtgaaattt   3840

tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg tttttaaaac   3900

tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc gtatgctggt   3960

tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag ttgttcgatc   4020

aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca gaggagaaaa   4080

ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta aggcaggagg   4140

accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct tacaaggctc   4200

taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta taaacaatac   4260

ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca taaaaggctc   4320

taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct agttatggtt   4380

actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag aaggagagat   4440

agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt cttcgtttga   4500

aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc ttttaaaata   4560

agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg agtcagtgga   4620

acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt gataagattt   4680

gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt ttgtttaaga   4740

gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa ttcatgaata   4800

cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc aatataacgt   4860

ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc caaagacaat   4920

gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt tctccattgg   4980

aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt tatctttttt   5040

cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata cactttattg   5100

c                                                                   5101


<210>  9748
<211>  876
<212>  PRT
<213>  Homo sapiens

<400>  9748

Met Met Arg Thr Gly Gly Thr Ile Lys Gly Ser Lys Val Thr Leu Leu 
1               5                   10                  15


Leu Ser Ser Lys Thr Glu Met Gln Asn Met Ile Glu Leu Ser Arg Arg 
            20                  25                  30


Arg Phe Glu Thr Ala Asn Leu Asp Ile Pro Pro Ala Asn Ala Ser Arg 
        35                  40                  45


Ser Gly Pro Pro Pro Ser Ser Gly Met Ser Ser Arg Val Asn Leu Pro 
    50                  55                  60


Thr Thr Val Ser Asn Phe Asn Asn Pro Ser Pro Ser Val Val Thr Ala 
65                  70                  75                  80


Thr Thr Ser Val His Glu Ser Asn Lys Asn Ile Gln Thr Phe Ser Thr 
                85                  90                  95


Ala Ser Val Gly Thr Ala Pro Pro Asn Met Gly Ala Ser Phe Gly Ser 
            100                 105                 110


Pro Thr Phe Ser Ser Thr Val Pro Ser Thr Ala Ser Pro Met Asn Thr 
        115                 120                 125


Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro Ser Leu Pro 
    130                 135                 140


Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr 
145                 150                 155                 160


Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val 
                165                 170                 175


Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn 
            180                 185                 190


Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala 
        195                 200                 205


Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu 
    210                 215                 220


Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro 
225                 230                 235                 240


Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro 
                245                 250                 255


Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg 
            260                 265                 270


Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly 
        275                 280                 285


Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu 
    290                 295                 300


Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro 
305                 310                 315                 320


Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys 
                325                 330                 335


Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu 
            340                 345                 350


Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser 
        355                 360                 365


Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu 
    370                 375                 380


Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val 
385                 390                 395                 400


Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly 
                405                 410                 415


Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu 
            420                 425                 430


Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro 
        435                 440                 445


Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg 
    450                 455                 460


Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu 
465                 470                 475                 480


Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro 
                485                 490                 495


Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro 
            500                 505                 510


Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly 
        515                 520                 525


Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys 
    530                 535                 540


Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val 
545                 550                 555                 560


His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro 
                565                 570                 575


Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala 
            580                 585                 590


Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser 
        595                 600                 605


Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser 
    610                 615                 620


Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly 
625                 630                 635                 640


Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser 
                645                 650                 655


Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly 
            660                 665                 670


Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly 
        675                 680                 685


Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser 
    690                 695                 700


Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro 
705                 710                 715                 720


Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe 
                725                 730                 735


Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly 
            740                 745                 750


Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala 
        755                 760                 765


Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile 
    770                 775                 780


Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr 
785                 790                 795                 800


Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile 
                805                 810                 815


Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu 
            820                 825                 830


Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe 
        835                 840                 845


Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg 
    850                 855                 860


Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
865                 870                 875


<210>  9749
<211>  4785
<212>  DNA
<213>  Homo sapiens

<400>  9749
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg gtttcagcgc    240

accagcgtag gaacagctcc tccaaatatg ggggcttcct ttgggagccc aacgtttagc    300

tcaactgttc caagcacagc ctctccaatg aacacagtcc cgccgccacc aattcctcca    360

attccagcga tgccatctct gccaccaatg ccatccattc ccccaattcc agttcctcct    420

ccagtaccta cattgcctcc tgtgcctcct gtgcccccga ttcccccagt tccttctgtg    480

ccacccatga ccccactgcc acccatgtcg ggcatgccgc ccttgaatcc gccacctgtg    540

gcacctctac ctgctggaat gaatggctct ggagcaccta tgaatttgaa caataatctg    600

aatcctatgt ttcttggtcc gttgaatcct gttaacccta tccagatgaa ctctcagagc    660

agtgtgaagc cactccccat caaccctgat gatctgtatg tcagtgtgca tggaatgccc    720

ttttctgcaa tggaaaatga tgtcagagat ttttttcatg ggctccgtgt tgatgcagtg    780

catttgttga aagatcatgt aggtcgaaat aatgggaatg gattggttaa gtttctctcc    840

cctcaagata catttgaagc tttgaaacga aacagaatgc tgatgattca acgctatgtg    900

gaagttagcc ctgccacaga aagacagtgg gtagctgctg gaggccatat cacttttaag    960

caaaatatgg gaccttctgg acaaactcat ccccctcctc agacacttcc caggtcaaaa   1020

tcgcccagtg ggcagaaaag atcaaggtca agatcaccac atgaggctgg tttttgtgtt   1080

tacttgaaag ggctaccatt tgaagcagaa aacaaacatg tcattgattt ttttaaaaag   1140

ctggatattg tggaagatag tatttatata gcttatggac ccaatgggaa agcaactggc   1200

gaaggctttg tagagttcag aaatgaggct gactataagg ctgctctgtg tcgtcataaa   1260

cagtacatgg gcaatcgctt tattcaagtt catccaatta ctaagaaagg tatgctagaa   1320

aagatagata tgattcgaaa aagactgcag aacttcagct atgaccagag ggaaatgata   1380

ctaaatccag agggggatgt caactctgcc aaagtctgtg cccacataac aaatattcca   1440

ttcagcatta caaagatgga tgttcttcag ttcctagaag gaatcccagt ggatgaaaat   1500

gctgtacatg ttcttgttga taacaatggg caaggtctag gacaggcatt ggttcagttt   1560

aaaaatgaag atgatgcacg taagtctgaa cgcttacacc gtaaaaaact taatgggaga   1620

gaagcttttg ttcatgtagt taccctagaa gatatgagag agattgagaa aaatccccct   1680

gcccaaggaa aaaagggatt aaagatgcct gtgccaggta atcctgcagt tccaggaatg   1740

cccaatgcgg gactgcccgg tgtgggactg cccagtgcag gacttcccgg tgcaggcctg   1800

cccagcacag gactgcctgg ttcagcaata accagtgcag gactgcctgg tgcgggaatg   1860

cccagtgcag gaatacctag tgcaggaggt gaagagcatg ccttcctgac tgtaggatca   1920

aaggaagcca ataatgggcc tccatttaac tttcctggta attttggtgg atcaaatgcc   1980

tttgggccac caatccctcc tccaggatta ggaggcgggg cctttggtga tgctaggcct   2040

ggtatgcctt cagttggaaa cagtggtttg cctggtctag gactggatgt tccgggtttt   2100

ggaggtggac caaacaattt aagtgggcca tcgggatttg gagggggccc tcagaatttt   2160

ggaaatggcc ctggtagctt aggcggtccc ccggggtttg gaagtggccc tcctggtctt   2220

ggaagtgccc ctgggcattt gggtgggcca ccagcttttg ggcctggccc cggccccggc   2280

cccggccctg gcccaatcca tattggtggt ccccctggct ttgcatctag ttctggaaaa   2340

ccaggaccga cagtaattaa agtgcaaaac atgcccttta ctgtgtctat tgatgagatt   2400

ttagatttct tttatggcta tcaagtaatc ccaggctcag tgtgtttaaa atacaatgaa   2460

aaaggtatgc ccacaggtga agccatggtg gcctttgagt ctcgggatga agccacagct   2520

gctgtcattg acttaaatga caggcctata ggttcaagaa aagtaaaact tgtattaggg   2580

tagccattca catcattttt tatagggtag atcttcatat tgctgtgatt aatgcatcca   2640

gattgttttc ctagtatttc caggttagaa cctgtggatt gtttcaattg catatagctt   2700

ggtttccata acatagagca ttggttgact gtttacagaa gactcactca ccaggataaa   2760

cattgctgta tgttacagta aagctatctg gagagaacac ataaatgatt ttggcatacc   2820

attagagaaa ccatttgtaa aactcaaatg accacataaa gcttatcaag gagtctagat   2880

tggttttgtt ttataccata tgggatgaag aaaatagaaa tgtcagtaga actcattgag   2940

ggtgctcttg ccagctgctg aaaatagaag ttggctactc tcagaatttg gtttaaagct   3000

ggacagattt gctttgttat agggtaaagc tttgtctaaa gtcctcattt tcttttaaaa   3060

ttgaataaaa tttctgtata cagattcatt gtatgtacct ttattgcttc ttaagggtcc   3120

ttgctgtata gacagtcctg cttcagaagt tgctgctttg tttgtctaat tgactcattt   3180

gtaaatgagc agaactgttt tgttggtttt tttccctaaa tataaaagtc cacacttcgt   3240

ttgtgctata acctcaaact ttgatttcta atgtcacact taaaactgtg tggaataaga   3300

cttttgccat aaaaataaac tatggagtcc tttatctacc agagcctttt tggtttgacc   3360

gccacgattt aggttagtca gtttaaaaat tgttcatgtt gtttggatgg tatcgaaaac   3420

cagaaaccac ttttaataat gtgtttaaga tacttgattt gaagtccttt tcatatggac   3480

taattgtagt atcaatttcc tcctgtcccg attatgtgaa attttggcct ttaaacaaag   3540

aggggcccat tcataagaaa gtgttatatc taggttttta aaactgaagt tgaaattatc   3600

tttgttagca gtagtagtat agaataaaag atccgtatgc tggttcgtag attgatacgt   3660

gttagtcctg ttatttggag gctttttggc atagttgttc gatcaggagc ctgtttacta   3720

aaagtcttca tacagagtac aagtgcagcc gccagaggag aaaattgaga ttcttgaccc   3780

tttcatactc ttttctttgg tattcaggac actaaggcag gaggaccaca tgagttctgg   3840

ttggtaagtg tccttgtcat gaaaacactt gccttacaag gctctaatta tgatttccct   3900

agtcagtgct ctgaagatgt gtcacattat attataaaca atacggaagg ggagataggt   3960

gagatgatat gaaaaacaaa ttttctcact gtcataaaag gctctaatta tggttacttt   4020

ccttgtgatg aaaaacttgg ccttacaggg ctctagttat ggttactttc cctagtcaat   4080

gctctgaaaa tgtgtcacat tataaacaat acagaaggag agatagatga gagatcatga   4140

aaaccaaatt ttatctttta catggcccct ttgtcttcgt ttgaaacatc cccaacattt   4200

cctacaaatc agcgtagtta caaaggggtc agtcttttaa aataagtatt tcctattaaa   4260

ctatatatat atacagtgcc tttttggtgt tgtgagtcag tggaacactg aaatacagcg   4320

gttgtgtaat ttaagagtgg caacagtttc atttgataag atttgaaaag gctttttatc   4380

actacaatct tagaggattg acagtacagg atttttgttt aagagaagga ttgtttagac   4440

tcaagaggtg actatgttgt gggtcttttg ataattcatg aatacagatt tgctttgacc   4500

gatcactaga tactgcctcc tcaatttcaa aagcaatata acgtttgtat atgctgttta   4560

atttaagtta atgttaagta atcatttctc attccaaaga caatgcaaaa aacttcagca   4620

ctgcttgaga gttgtatttc agccacagat attttctcca ttggaaagct attttcattt   4680

tagaaaaatg ggttgtttga agatgaaagt cttttatctt ttttcacaat ttattttggt   4740

tatatgttcg tacattctta ttaaatattt catacacttt attgc                   4785


<210>  9750
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9750

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9751
<211>  5168
<212>  DNA
<213>  Homo sapiens

<400>  9751
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccggtgtg tgtggtttca gcgcagcatg gctgtggtca    180

tccgtttgca aggtctccca attgtggcgg ggaccatgga cattcgccac ttcttctctg    240

gattgaccat tcctgatggg ggcgtgcata ttgtaggggg tgaactgggt gaggctttca    300

tcgtttttgc cactgatgaa gatgcaaggc ttggtatgat gcgcacaggt ggtacaatta    360

aagggtcaaa agtaacacta ttgttgagta gtaagacgga aatgcagaat atgattgaac    420

tgagtcgtag gcgttttgaa actgccaact tagatatacc accagcaaat gccagtagat    480

caggaccacc acctagctca ggaatgagta gcagggtaaa cttgcccaca acagtatcca    540

actttaataa tccatcaccc agtgtagtta ctgccaccac ttctgttcat gaaagcaaca    600

aaaacataca gacattttcc acagccagcg taggaacagc tcctccaaat atgggggctt    660

cctttgggag cccaacgttt agctcaactg ttccaagcac agcctctcca atgaacacag    720

tcccgccgcc accaattcct ccaattccag cgatgccatc tctgccacca atgccatcca    780

ttcccccaat tccagttcct cctccagtac ctacattgcc tcctgtgcct cctgtgcccc    840

cgattccccc agttccttct gtgccaccca tgaccccact gccacccatg tcgggcatgc    900

cgcccttgaa tccgccacct gtggcacctc tacctgctgg aatgaatggc tctggagcac    960

ctatgaattt gaacaataat ctgaatccta tgtttcttgg tccgttgaat cctgttaacc   1020

ctatccagat gaactctcag agcagtgtga agccactccc catcaaccct gatgatctgt   1080

atgtcagtgt gcatggaatg cccttttctg caatggaaaa tgatgtcaga gatttttttc   1140

atgggctccg tgttgatgca gtgcatttgt tgaaagatca tgtaggtcga aataatggga   1200

atggattggt taagtttctc tcccctcaag atacatttga agctttgaaa cgaaacagaa   1260

tgctgatgat tcaacgctat gtggaagtta gccctgccac agaaagacag tgggtagctg   1320

ctggaggcca tatcactttt aagcaaaata tgggaccttc tggacaaact catccccctc   1380

ctcagacact tcccaggtca aaatcgccca gtgggcagaa aagatcaagg tcaagatcac   1440

cacatgaggc tggtttttgt gtttacttga aagggctacc atttgaagca gaaaacaaac   1500

atgtcattga tttttttaaa aagctggata ttgtggaaga tagtatttat atagcttatg   1560

gacccaatgg gaaagcaact ggcgaaggct ttgtagagtt cagaaatgag gctgactata   1620

aggctgctct gtgtcgtcat aaacagtaca tgggcaatcg ctttattcaa gttcatccaa   1680

ttactaagaa aggtatgcta gaaaagatag atatgattcg aaaaagactg cagaacttca   1740

gctatgacca gagggaaatg atactaaatc cagaggggga tgtcaactct gccaaagtct   1800

gtgcccacat aacaaatatt ccattcagca ttacaaagat ggatgttctt cagttcctag   1860

aaggaatccc agtggatgaa aatgctgtac atgttcttgt tgataacaat gggcaaggtc   1920

taggacaggc attggttcag tttaaaaatg aagatgatgc acgtaagtct gaacgcttac   1980

accgtaaaaa acttaatggg agagaagctt ttgttcatgt agttacccta gaagatatga   2040

gagagattga gaaaaatccc cctgcccaag gaaaaaaggg attaaagatg cctgtgccag   2100

gtaatcctgc agttccagga atgcccaatg cgggactgcc cggtgtggga ctgcccagtg   2160

caggacttcc cggtgcaggc ctgcccagca caggactgcc tggttcagca ataaccagtg   2220

caggactgcc tggtgcggga atgcccagtg caggaatacc tagtgcagga ggtgaagagc   2280

atgccttcct gactgtagga tcaaaggaag ccaataatgg gcctccattt aactttcctg   2340

gtaattttgg tggatcaaat gcctttgggc caccaatccc tcctccagga ttaggaggcg   2400

gggcctttgg tgatgctagg cctggtatgc cttcagttgg aaacagtggt ttgcctggtc   2460

taggactgga tgttccgggt tttggaggtg gaccaaacaa tttaagtggg ccatcgggat   2520

ttggaggggg ccctcagaat tttggaaatg gccctggtag cttaggcggt cccccggggt   2580

ttggaagtgg ccctcctggt cttggaagtg cccctgggca tttgggtggg ccaccagctt   2640

ttgggcctgg ccccggcccc ggccccggcc ctggcccaat ccatattggt ggtccccctg   2700

gctttgcatc tagttctgga aaaccaggac cgacagtaat taaagtgcaa aacatgccct   2760

ttactgtgtc tattgatgag attttagatt tcttttatgg ctatcaagta atcccaggct   2820

cagtgtgttt aaaatacaat gaaaaaggta tgcccacagg tgaagccatg gtggcctttg   2880

agtctcggga tgaagccaca gctgctgtca ttgacttaaa tgacaggcct ataggttcaa   2940

gaaaagtaaa acttgtatta gggtagccat tcacatcatt ttttataggg tagatcttca   3000

tattgctgtg attaatgcat ccagattgtt ttcctagtat ttccaggtta gaacctgtgg   3060

attgtttcaa ttgcatatag cttggtttcc ataacataga gcattggttg actgtttaca   3120

gaagactcac tcaccaggat aaacattgct gtatgttaca gtaaagctat ctggagagaa   3180

cacataaatg attttggcat accattagag aaaccatttg taaaactcaa atgaccacat   3240

aaagcttatc aaggagtcta gattggtttt gttttatacc atatgggatg aagaaaatag   3300

aaatgtcagt agaactcatt gagggtgctc ttgccagctg ctgaaaatag aagttggcta   3360

ctctcagaat ttggtttaaa gctggacaga tttgctttgt tatagggtaa agctttgtct   3420

aaagtcctca ttttctttta aaattgaata aaatttctgt atacagattc attgtatgta   3480

cctttattgc ttcttaaggg tccttgctgt atagacagtc ctgcttcaga agttgctgct   3540

ttgtttgtct aattgactca tttgtaaatg agcagaactg ttttgttggt ttttttccct   3600

aaatataaaa gtccacactt cgtttgtgct ataacctcaa actttgattt ctaatgtcac   3660

acttaaaact gtgtggaata agacttttgc cataaaaata aactatggag tcctttatct   3720

accagagcct ttttggtttg accgccacga tttaggttag tcagtttaaa aattgttcat   3780

gttgtttgga tggtatcgaa aaccagaaac cacttttaat aatgtgttta agatacttga   3840

tttgaagtcc ttttcatatg gactaattgt agtatcaatt tcctcctgtc ccgattatgt   3900

gaaattttgg cctttaaaca aagaggggcc cattcataag aaagtgttat atctaggttt   3960

ttaaaactga agttgaaatt atctttgtta gcagtagtag tatagaataa aagatccgta   4020

tgctggttcg tagattgata cgtgttagtc ctgttatttg gaggcttttt ggcatagttg   4080

ttcgatcagg agcctgttta ctaaaagtct tcatacagag tacaagtgca gccgccagag   4140

gagaaaattg agattcttga ccctttcata ctcttttctt tggtattcag gacactaagg   4200

caggaggacc acatgagttc tggttggtaa gtgtccttgt catgaaaaca cttgccttac   4260

aaggctctaa ttatgatttc cctagtcagt gctctgaaga tgtgtcacat tatattataa   4320

acaatacgga aggggagata ggtgagatga tatgaaaaac aaattttctc actgtcataa   4380

aaggctctaa ttatggttac tttccttgtg atgaaaaact tggccttaca gggctctagt   4440

tatggttact ttccctagtc aatgctctga aaatgtgtca cattataaac aatacagaag   4500

gagagataga tgagagatca tgaaaaccaa attttatctt ttacatggcc cctttgtctt   4560

cgtttgaaac atccccaaca tttcctacaa atcagcgtag ttacaaaggg gtcagtcttt   4620

taaaataagt atttcctatt aaactatata tatatacagt gcctttttgg tgttgtgagt   4680

cagtggaaca ctgaaataca gcggttgtgt aatttaagag tggcaacagt ttcatttgat   4740

aagatttgaa aaggcttttt atcactacaa tcttagagga ttgacagtac aggatttttg   4800

tttaagagaa ggattgttta gactcaagag gtgactatgt tgtgggtctt ttgataattc   4860

atgaatacag atttgctttg accgatcact agatactgcc tcctcaattt caaaagcaat   4920

ataacgtttg tatatgctgt ttaatttaag ttaatgttaa gtaatcattt ctcattccaa   4980

agacaatgca aaaaacttca gcactgcttg agagttgtat ttcagccaca gatattttct   5040

ccattggaaa gctattttca ttttagaaaa atgggttgtt tgaagatgaa agtcttttat   5100

cttttttcac aatttatttt ggttatatgt tcgtacattc ttattaaata tttcatacac   5160

tttattgc                                                            5168


<210>  9752
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9752

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9753
<211>  4430
<212>  DNA
<213>  Homo sapiens

<400>  9753
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccgtctaa aagttggttt taattggttg cccacaggat    180

tgacttggcc tctacctgct ggaatgaatg gctctggagc acctatgaat ttgaacaata    240

atctgaatcc tatgtttctt ggtccgttga atcctgttaa ccctatccag atgaactctc    300

agagcagtgt gaagccactc cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa    360

tgcccttttc tgcaatggaa aatgatgtca gagatttttt tcatgggctc cgtgttgatg    420

cagtgcattt gttgaaagat catgtaggtc gaaataatgg gaatggattg gttaagtttc    480

tctcccctca agatacattt gaagctttga aacgaaacag aatgctgatg attcaacgct    540

atgtggaagt tagccctgcc acagaaagac agtgggtagc tgctggaggc catatcactt    600

ttaagcaaaa tatgggacct tctggacaaa ctcatccccc tcctcagaca cttcccaggt    660

caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc accacatgag gctggttttt    720

gtgtttactt gaaagggcta ccatttgaag cagaaaacaa acatgtcatt gattttttta    780

aaaagctgga tattgtggaa gatagtattt atatagctta tggacccaat gggaaagcaa    840

ctggcgaagg ctttgtagag ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc    900

ataaacagta catgggcaat cgctttattc aagttcatcc aattactaag aaaggtatgc    960

tagaaaagat agatatgatt cgaaaaagac tgcagaactt cagctatgac cagagggaaa   1020

tgatactaaa tccagagggg gatgtcaact ctgccaaagt ctgtgcccac ataacaaata   1080

ttccattcag cattacaaag atggatgttc ttcagttcct agaaggaatc ccagtggatg   1140

aaaatgctgt acatgttctt gttgataaca atgggcaagg tctaggacag gcattggttc   1200

agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg   1260

ggagagaagc ttttgttcat gtagttaccc tagaagatat gagagagatt gagaaaaatc   1320

cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc aggtaatcct gcagttccag   1380

gaatgcccaa tgcgggactg cccggtgtgg gactgcccag tgcaggactt cccggtgcag   1440

gcctgcccag cacaggactg cctggttcag caataaccag tgcaggactg cctggtgcgg   1500

gaatgcccag tgcaggaata cctagtgcag gaggtgaaga gcatgccttc ctgactgtag   1560

gatcaaagga agccaataat gggcctccat ttaactttcc tggtaatttt ggtggatcaa   1620

atgcctttgg gccaccaatc cctcctccag gattaggagg cggggccttt ggtgatgcta   1680

ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg tctaggactg gatgttccgg   1740

gttttggagg tggaccaaac aatttaagtg ggccatcggg atttggaggg ggccctcaga   1800

attttggaaa tggccctggt agcttaggcg gtcccccggg gtttggaagt ggccctcctg   1860

gtcttggaag tgcccctggg catttgggtg ggccaccagc ttttgggcct ggccccggcc   1920

ccggccccgg ccctggccca atccatattg gtggtccccc tggctttgca tctagttctg   1980

gaaaaccagg accgacagta attaaagtgc aaaacatgcc ctttactgtg tctattgatg   2040

agattttaga tttcttttat ggctatcaag taatcccagg ctcagtgtgt ttaaaataca   2100

atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca   2160

cagctgctgt cattgactta aatgacaggc ctataggttc aagaaaagta aaacttgtat   2220

tagggtagcc attcacatca ttttttatag ggtagatctt catattgctg tgattaatgc   2280

atccagattg ttttcctagt atttccaggt tagaacctgt ggattgtttc aattgcatat   2340

agcttggttt ccataacata gagcattggt tgactgttta cagaagactc actcaccagg   2400

ataaacattg ctgtatgtta cagtaaagct atctggagag aacacataaa tgattttggc   2460

ataccattag agaaaccatt tgtaaaactc aaatgaccac ataaagctta tcaaggagtc   2520

tagattggtt ttgttttata ccatatggga tgaagaaaat agaaatgtca gtagaactca   2580

ttgagggtgc tcttgccagc tgctgaaaat agaagttggc tactctcaga atttggttta   2640

aagctggaca gatttgcttt gttatagggt aaagctttgt ctaaagtcct cattttcttt   2700

taaaattgaa taaaatttct gtatacagat tcattgtatg tacctttatt gcttcttaag   2760

ggtccttgct gtatagacag tcctgcttca gaagttgctg ctttgtttgt ctaattgact   2820

catttgtaaa tgagcagaac tgttttgttg gtttttttcc ctaaatataa aagtccacac   2880

ttcgtttgtg ctataacctc aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa   2940

taagactttt gccataaaaa taaactatgg agtcctttat ctaccagagc ctttttggtt   3000

tgaccgccac gatttaggtt agtcagttta aaaattgttc atgttgtttg gatggtatcg   3060

aaaaccagaa accactttta ataatgtgtt taagatactt gatttgaagt ccttttcata   3120

tggactaatt gtagtatcaa tttcctcctg tcccgattat gtgaaatttt ggcctttaaa   3180

caaagagggg cccattcata agaaagtgtt atatctaggt ttttaaaact gaagttgaaa   3240

ttatctttgt tagcagtagt agtatagaat aaaagatccg tatgctggtt cgtagattga   3300

tacgtgttag tcctgttatt tggaggcttt ttggcatagt tgttcgatca ggagcctgtt   3360

tactaaaagt cttcatacag agtacaagtg cagccgccag aggagaaaat tgagattctt   3420

gaccctttca tactcttttc tttggtattc aggacactaa ggcaggagga ccacatgagt   3480

tctggttggt aagtgtcctt gtcatgaaaa cacttgcctt acaaggctct aattatgatt   3540

tccctagtca gtgctctgaa gatgtgtcac attatattat aaacaatacg gaaggggaga   3600

taggtgagat gatatgaaaa acaaattttc tcactgtcat aaaaggctct aattatggtt   3660

actttccttg tgatgaaaaa cttggcctta cagggctcta gttatggtta ctttccctag   3720

tcaatgctct gaaaatgtgt cacattataa acaatacaga aggagagata gatgagagat   3780

catgaaaacc aaattttatc ttttacatgg cccctttgtc ttcgtttgaa acatccccaa   3840

catttcctac aaatcagcgt agttacaaag gggtcagtct tttaaaataa gtatttccta   3900

ttaaactata tatatataca gtgccttttt ggtgttgtga gtcagtggaa cactgaaata   3960

cagcggttgt gtaatttaag agtggcaaca gtttcatttg ataagatttg aaaaggcttt   4020

ttatcactac aatcttagag gattgacagt acaggatttt tgtttaagag aaggattgtt   4080

tagactcaag aggtgactat gttgtgggtc ttttgataat tcatgaatac agatttgctt   4140

tgaccgatca ctagatactg cctcctcaat ttcaaaagca atataacgtt tgtatatgct   4200

gtttaattta agttaatgtt aagtaatcat ttctcattcc aaagacaatg caaaaaactt   4260

cagcactgct tgagagttgt atttcagcca cagatatttt ctccattgga aagctatttt   4320

cattttagaa aaatgggttg tttgaagatg aaagtctttt atcttttttc acaatttatt   4380

ttggttatat gttcgtacat tcttattaaa tatttcatac actttattgc              4430


<210>  9754
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  9754

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala 
        275                 280                 285


His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln 
    290                 295                 300


Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val 
305                 310                 315                 320


Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn 
                325                 330                 335


Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn 
            340                 345                 350


Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu 
        355                 360                 365


Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro 
    370                 375                 380


Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro 
385                 390                 395                 400


Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser 
                405                 410                 415


Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala 
            420                 425                 430


Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala 
        435                 440                 445


Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn 
    450                 455                 460


Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro 
465                 470                 475                 480


Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met 
                485                 490                 495


Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro 
            500                 505                 510


Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly 
        515                 520                 525


Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro 
    530                 535                 540


Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His 
545                 550                 555                 560


Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly 
                565                 570                 575


Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser 
            580                 585                 590


Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr 
        595                 600                 605


Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile 
    610                 615                 620


Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly 
625                 630                 635                 640


Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val 
                645                 650                 655


Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val 
            660                 665                 670


Leu Gly 



<210>  9755
<211>  4151
<212>  DNA
<213>  Homo sapiens

<400>  9755
ggaacgcgga gccgctgagc gggccgacgg ccattttgtg aagcggcgaa ggaggtggtg     60

gctgcgttgg gctccgggaa gccgttcggg ctggggctgt cggccgcggg gcggaggcac    120

tcgcgcgggg gtctaaaagt tggttttaat tggttgccca caggattgac ttggcctcta    180

cttcttgtta aggaaattca tctcttgttt tatcaggtgt gtgtggtttc agcgcagcat    240

ggctgtggtc atccgtttgc aaggtctccc aattgtggcg gggaccatgg acattcgcca    300

cttcttctct ggattgacca ttcctgatgg gggcgtgcat attgtagggg gtgaactggg    360

tgaggctttc atcgtttttg ccactgatga agatgcaagg cttggtatga tgcgcacagg    420

tggtacaatt aaagggtcaa aagtaacact attgttgagt agtaagacgg aaatgcagaa    480

tatgattgaa ctgatttttt aaaaagctgg atattgtgga agatagtatt tatatagctt    540

atggacccaa tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact    600

ataaggctgc tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc    660

caattactaa gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact    720

tcagctatga ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag    780

tctgtgccca cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc    840

tagaaggaat cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag    900

gtctaggaca ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct    960

tacaccgtaa aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata   1020

tgagagagat tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc   1080

caggtaatcc tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca   1140

gtgcaggact tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca   1200

gtgcaggact gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag   1260

agcatgcctt cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc   1320

ctggtaattt tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag   1380

gcggggcctt tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg   1440

gtctaggact ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg   1500

gatttggagg gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg   1560

ggtttggaag tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag   1620

cttttgggcc tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc   1680

ctggctttgc atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc   1740

cctttactgt gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag   1800

gctcagtgtg tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct   1860

ttgagtctcg ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt   1920

caagaaaagt aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct   1980

tcatattgct gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg   2040

tggattgttt caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt   2100

acagaagact cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga   2160

gaacacataa atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca   2220

cataaagctt atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa   2280

tagaaatgtc agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg   2340

ctactctcag aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg   2400

tctaaagtcc tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat   2460

gtacctttat tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct   2520

gctttgtttg tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc   2580

cctaaatata aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt   2640

cacacttaaa actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta   2700

tctaccagag cctttttggt ttgaccgcca cgatttaggt tagtcagttt aaaaattgtt   2760

catgttgttt ggatggtatc gaaaaccaga aaccactttt aataatgtgt ttaagatact   2820

tgatttgaag tccttttcat atggactaat tgtagtatca atttcctcct gtcccgatta   2880

tgtgaaattt tggcctttaa acaaagaggg gcccattcat aagaaagtgt tatatctagg   2940

tttttaaaac tgaagttgaa attatctttg ttagcagtag tagtatagaa taaaagatcc   3000

gtatgctggt tcgtagattg atacgtgtta gtcctgttat ttggaggctt tttggcatag   3060

ttgttcgatc aggagcctgt ttactaaaag tcttcataca gagtacaagt gcagccgcca   3120

gaggagaaaa ttgagattct tgaccctttc atactctttt ctttggtatt caggacacta   3180

aggcaggagg accacatgag ttctggttgg taagtgtcct tgtcatgaaa acacttgcct   3240

tacaaggctc taattatgat ttccctagtc agtgctctga agatgtgtca cattatatta   3300

taaacaatac ggaaggggag ataggtgaga tgatatgaaa aacaaatttt ctcactgtca   3360

taaaaggctc taattatggt tactttcctt gtgatgaaaa acttggcctt acagggctct   3420

agttatggtt actttcccta gtcaatgctc tgaaaatgtg tcacattata aacaatacag   3480

aaggagagat agatgagaga tcatgaaaac caaattttat cttttacatg gcccctttgt   3540

cttcgtttga aacatcccca acatttccta caaatcagcg tagttacaaa ggggtcagtc   3600

ttttaaaata agtatttcct attaaactat atatatatac agtgcctttt tggtgttgtg   3660

agtcagtgga acactgaaat acagcggttg tgtaatttaa gagtggcaac agtttcattt   3720

gataagattt gaaaaggctt tttatcacta caatcttaga ggattgacag tacaggattt   3780

ttgtttaaga gaaggattgt ttagactcaa gaggtgacta tgttgtgggt cttttgataa   3840

ttcatgaata cagatttgct ttgaccgatc actagatact gcctcctcaa tttcaaaagc   3900

aatataacgt ttgtatatgc tgtttaattt aagttaatgt taagtaatca tttctcattc   3960

caaagacaat gcaaaaaact tcagcactgc ttgagagttg tatttcagcc acagatattt   4020

tctccattgg aaagctattt tcattttaga aaaatgggtt gtttgaagat gaaagtcttt   4080

tatctttttt cacaatttat tttggttata tgttcgtaca ttcttattaa atatttcata   4140

cactttattg c                                                        4151


<210>  9756
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9756

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ile Phe 
                85


<210>  9757
<211>  5240
<212>  DNA
<213>  Homo sapiens

<400>  9757
tggaacgcgg agccgctgag cgggccgacg gccattttgt gaagcggcga aggaggtggt     60

ggctgcgttg ggctccggga agccgttcgg gctggggctg tcggccgcgg ggcggaggca    120

ctcgcgcggg ggtctaaaag ttggttttaa ttggttgccc acaggattga cttggcctct    180

acttcttgtt aaggaaattc atctcttgtt ttatcaggtg tgtgtggttt cagcgcagca    240

tggctgtggt catccgtttg caaggtctcc caattgtggc ggggaccatg gacattcgcc    300

acttcttctc tggattgacc attcctgatg ggggcgtgca tattgtaggg ggtgaactgg    360

gtgaggcttt catcgttttt gccactgatg aagatgcaag gcttggtatg atgcgcacag    420

gtggtacaat taaagggtca aaagtaacac tattgttgag tagtaagacg gaaatgcaga    480

atatgattga actgagtcgt aggcgttttg aaactgccaa cttagatata ccaccagcaa    540

atgccagtag atcaggacca ccacctagct caggaatgag tagcagggta aacttgccca    600

caacagtatc caactttaat aatccatcac ccagtgtagt tactgccacc acttctgttc    660

atgaaagcaa caaaaacata cagacatttt ccacagccag cgtaggaaca gctcctccaa    720

atatgggggc ttcctttggg agcccaacgt ttagctcaac tgttccaagc acagcctctc    780

caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca tctctgccac    840

caatgccatc cattccccca attccagttc ctcctccagt acctacattg cctcctgtgc    900

ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca ctgccaccca    960

tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg   1020

gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga   1080

atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc   1140

ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca   1200

gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc   1260

gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga   1320

aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac   1380

agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa   1440

ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa   1500

ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag   1560

cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt   1620

atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg   1680

aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc   1740

aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac   1800

tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact   1860

ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc   1920

ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca   1980

atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt   2040

ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc   2100

tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga   2160

tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg   2220

gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag   2280

caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag   2340

gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat   2400

ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag   2460

gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg   2520

gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg   2580

ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg   2640

gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg   2700

ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg   2760

gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc   2820

aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag   2880

taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca   2940

tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc   3000

ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag   3060

ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt   3120

tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt   3180

tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct   3240

atctggagag aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc   3300

aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga   3360

tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat   3420

agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt   3480

aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat   3540

tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca   3600

gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg   3660

gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat   3720

ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg   3780

agtcctttat ctaccagagc ctttttggtt tgaccgccac gatttaggtt agtcagttta   3840

aaaattgttc atgttgtttg gatggtatcg aaaaccagaa accactttta ataatgtgtt   3900

taagatactt gatttgaagt ccttttcata tggactaatt gtagtatcaa tttcctcctg   3960

tcccgattat gtgaaatttt ggcctttaaa caaagagggg cccattcata agaaagtgtt   4020

atatctaggt ttttaaaact gaagttgaaa ttatctttgt tagcagtagt agtatagaat   4080

aaaagatccg tatgctggtt cgtagattga tacgtgttag tcctgttatt tggaggcttt   4140

ttggcatagt tgttcgatca ggagcctgtt tactaaaagt cttcatacag agtacaagtg   4200

cagccgccag aggagaaaat tgagattctt gaccctttca tactcttttc tttggtattc   4260

aggacactaa ggcaggagga ccacatgagt tctggttggt aagtgtcctt gtcatgaaaa   4320

cacttgcctt acaaggctct aattatgatt tccctagtca gtgctctgaa gatgtgtcac   4380

attatattat aaacaatacg gaaggggaga taggtgagat gatatgaaaa acaaattttc   4440

tcactgtcat aaaaggctct aattatggtt actttccttg tgatgaaaaa cttggcctta   4500

cagggctcta gttatggtta ctttccctag tcaatgctct gaaaatgtgt cacattataa   4560

acaatacaga aggagagata gatgagagat catgaaaacc aaattttatc ttttacatgg   4620

cccctttgtc ttcgtttgaa acatccccaa catttcctac aaatcagcgt agttacaaag   4680

gggtcagtct tttaaaataa gtatttccta ttaaactata tatatataca gtgccttttt   4740

ggtgttgtga gtcagtggaa cactgaaata cagcggttgt gtaatttaag agtggcaaca   4800

gtttcatttg ataagatttg aaaaggcttt ttatcactac aatcttagag gattgacagt   4860

acaggatttt tgtttaagag aaggattgtt tagactcaag aggtgactat gttgtgggtc   4920

ttttgataat tcatgaatac agatttgctt tgaccgatca ctagatactg cctcctcaat   4980

ttcaaaagca atataacgtt tgtatatgct gtttaattta agttaatgtt aagtaatcat   5040

ttctcattcc aaagacaatg caaaaaactt cagcactgct tgagagttgt atttcagcca   5100

cagatatttt ctccattgga aagctatttt cattttagaa aaatgggttg tttgaagatg   5160

aaagtctttt atcttttttc acaatttatt ttggttatat gttcgtacat tcttattaaa   5220

tatttcatac actttattgc                                               5240


<210>  9758
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9758

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9759
<211>  5286
<212>  DNA
<213>  Homo sapiens

<400>  9759
cttctggaac gcggagccgc tgagcgggcc gacggccatt ttgtgaagcg gcgaaggagg     60

tggtggctgc gttgggctcc gggaagccgt tcgggctggg gctgtcggcc gcggggcgga    120

ggcactcgcg cggggggtaa ttcggggtct gggttctggt gccgcgcagc tttccccgtc    180

taaaagttgg ttttaattgg ttgcccacag gattgacttg gcctctactt cttgttaagg    240

aaattcatct cttgttttat caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc    300

cgtttgcaag gtctcccaat tgtggcgggg accatggaca ttcgccactt cttctctgga    360

ttgaccattc ctgatggggg cgtgcatatt gtagggggtg aactgggtga ggctttcatc    420

gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa    480

gggtcaaaag taacactatt gttgagtagt aagacggaaa tgcagaatat gattgaactg    540

agtcgtaggc gttttgaaac tgccaactta gatataccac cagcaaatgc cagtagatca    600

ggaccaccac ctagctcagg aatgagtagc agggtaaact tgcccacaac agtatccaac    660

tttaataatc catcacccag tgtagttact gccaccactt ctgttcatga aagcaacaaa    720

aacatacaga cattttccac agccagcgta ggaacagctc ctccaaatat gggggcttcc    780

tttgggagcc caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc    840

ccgccgccac caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt    900

cccccaattc cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg    960

attcccccag ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg   1020

cccttgaatc cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct   1080

atgaatttga acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct   1140

atccagatga actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat   1200

gtcagtgtgc atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat   1260

gggctccgtg ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat   1320

ggattggtta agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg   1380

ctgatgattc aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct   1440

ggaggccata tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct   1500

cagacacttc ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca   1560

catgaggctg gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat   1620

gtcattgatt tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga   1680

cccaatggga aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag   1740

gctgctctgt gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt   1800

actaagaaag gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc   1860

tatgaccaga gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt   1920

gcccacataa caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa   1980

ggaatcccag tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta   2040

ggacaggcat tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac   2100

cgtaaaaaac ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga   2160

gagattgaga aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt   2220

aatcctgcag ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca   2280

ggacttcccg gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca   2340

ggactgcctg gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat   2400

gccttcctga ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt   2460

aattttggtg gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg   2520

gcctttggtg atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta   2580

ggactggatg ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt   2640

ggagggggcc ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt   2700

ggaagtggcc ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt   2760

gggcctggcc ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc   2820

tttgcatcta gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt   2880

actgtgtcta ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca   2940

gtgtgtttaa aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag   3000

tctcgggatg aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga   3060

aaagtaaaac ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata   3120

ttgctgtgat taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat   3180

tgtttcaatt gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga   3240

agactcactc accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca   3300

cataaatgat tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa   3360

agcttatcaa ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa   3420

atgtcagtag aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact   3480

ctcagaattt ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa   3540

agtcctcatt ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc   3600

tttattgctt cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt   3660

gtttgtctaa ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa   3720

atataaaagt ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac   3780

ttaaaactgt gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatctac   3840

cagagccttt ttggtttgac cgccacgatt taggttagtc agtttaaaaa ttgttcatgt   3900

tgtttggatg gtatcgaaaa ccagaaacca cttttaataa tgtgtttaag atacttgatt   3960

tgaagtcctt ttcatatgga ctaattgtag tatcaatttc ctcctgtccc gattatgtga   4020

aattttggcc tttaaacaaa gaggggccca ttcataagaa agtgttatat ctaggttttt   4080

aaaactgaag ttgaaattat ctttgttagc agtagtagta tagaataaaa gatccgtatg   4140

ctggttcgta gattgatacg tgttagtcct gttatttgga ggctttttgg catagttgtt   4200

cgatcaggag cctgtttact aaaagtcttc atacagagta caagtgcagc cgccagagga   4260

gaaaattgag attcttgacc ctttcatact cttttctttg gtattcagga cactaaggca   4320

ggaggaccac atgagttctg gttggtaagt gtccttgtca tgaaaacact tgccttacaa   4380

ggctctaatt atgatttccc tagtcagtgc tctgaagatg tgtcacatta tattataaac   4440

aatacggaag gggagatagg tgagatgata tgaaaaacaa attttctcac tgtcataaaa   4500

ggctctaatt atggttactt tccttgtgat gaaaaacttg gccttacagg gctctagtta   4560

tggttacttt ccctagtcaa tgctctgaaa atgtgtcaca ttataaacaa tacagaagga   4620

gagatagatg agagatcatg aaaaccaaat tttatctttt acatggcccc tttgtcttcg   4680

tttgaaacat ccccaacatt tcctacaaat cagcgtagtt acaaaggggt cagtctttta   4740

aaataagtat ttcctattaa actatatata tatacagtgc ctttttggtg ttgtgagtca   4800

gtggaacact gaaatacagc ggttgtgtaa tttaagagtg gcaacagttt catttgataa   4860

gatttgaaaa ggctttttat cactacaatc ttagaggatt gacagtacag gatttttgtt   4920

taagagaagg attgtttaga ctcaagaggt gactatgttg tgggtctttt gataattcat   4980

gaatacagat ttgctttgac cgatcactag atactgcctc ctcaatttca aaagcaatat   5040

aacgtttgta tatgctgttt aatttaagtt aatgttaagt aatcatttct cattccaaag   5100

acaatgcaaa aaacttcagc actgcttgag agttgtattt cagccacaga tattttctcc   5160

attggaaagc tattttcatt ttagaaaaat gggttgtttg aagatgaaag tcttttatct   5220

tttttcacaa tttattttgg ttatatgttc gtacattctt attaaatatt tcatacactt   5280

tattgc                                                              5286


<210>  9760
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9760

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9761
<211>  5154
<212>  DNA
<213>  Homo sapiens

<400>  9761
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggagga ttgacttggc ctctacttct tgttaaggaa attcatctct    120

tgttttatca ggtgtgtgtg gtttcagcgc agcatggctg tggtcatccg tttgcaaggt    180

ctcccaattg tggcggggac catggacatt cgccacttct tctctggatt gaccattcct    240

gatgggggcg tgcatattgt agggggtgaa ctgggtgagg ctttcatcgt ttttgccact    300

gatgaagatg caaggcttgg tatgatgcgc acaggtggta caattaaagg gtcaaaagta    360

acactattgt tgagtagtaa gacggaaatg cagaatatga ttgaactgag tcgtaggcgt    420

tttgaaactg ccaacttaga tataccacca gcaaatgcca gtagatcagg accaccacct    480

agctcaggaa tgagtagcag ggtaaacttg cccacaacag tatccaactt taataatcca    540

tcacccagtg tagttactgc caccacttct gttcatgaaa gcaacaaaaa catacagaca    600

ttttccacag ccagcgtagg aacagctcct ccaaatatgg gggcttcctt tgggagccca    660

acgtttagct caactgttcc aagcacagcc tctccaatga acacagtccc gccgccacca    720

attcctccaa ttccagcgat gccatctctg ccaccaatgc catccattcc cccaattcca    780

gttcctcctc cagtacctac attgcctcct gtgcctcctg tgcccccgat tcccccagtt    840

ccttctgtgc cacccatgac cccactgcca cccatgtcgg gcatgccgcc cttgaatccg    900

ccacctgtgg cacctctacc tgctggaatg aatggctctg gagcacctat gaatttgaac    960

aataatctga atcctatgtt tcttggtccg ttgaatcctg ttaaccctat ccagatgaac   1020

tctcagagca gtgtgaagcc actccccatc aaccctgatg atctgtatgt cagtgtgcat   1080

ggaatgccct tttctgcaat ggaaaatgat gtcagagatt tttttcatgg gctccgtgtt   1140

gatgcagtgc atttgttgaa agatcatgta ggtcgaaata atgggaatgg attggttaag   1200

tttctctccc ctcaagatac atttgaagct ttgaaacgaa acagaatgct gatgattcaa   1260

cgctatgtgg aagttagccc tgccacagaa agacagtggg tagctgctgg aggccatatc   1320

acttttaagc aaaatatggg accttctgga caaactcatc cccctcctca gacacttccc   1380

aggtcaaaat cgcccagtgg gcagaaaaga tcaaggtcaa gatcaccaca tgaggctggt   1440

ttttgtgttt acttgaaagg gctaccattt gaagcagaaa acaaacatgt cattgatttt   1500

tttaaaaagc tggatattgt ggaagatagt atttatatag cttatggacc caatgggaaa   1560

gcaactggcg aaggctttgt agagttcaga aatgaggctg actataaggc tgctctgtgt   1620

cgtcataaac agtacatggg caatcgcttt attcaagttc atccaattac taagaaaggt   1680

atgctagaaa agatagatat gattcgaaaa agactgcaga acttcagcta tgaccagagg   1740

gaaatgatac taaatccaga gggggatgtc aactctgcca aagtctgtgc ccacataaca   1800

aatattccat tcagcattac aaagatggat gttcttcagt tcctagaagg aatcccagtg   1860

gatgaaaatg ctgtacatgt tcttgttgat aacaatgggc aaggtctagg acaggcattg   1920

gttcagttta aaaatgaaga tgatgcacgt aagtctgaac gcttacaccg taaaaaactt   1980

aatgggagag aagcttttgt tcatgtagtt accctagaag atatgagaga gattgagaaa   2040

aatccccctg cccaaggaaa aaagggatta aagatgcctg tgccaggtaa tcctgcagtt   2100

ccaggaatgc ccaatgcggg actgcccggt gtgggactgc ccagtgcagg acttcccggt   2160

gcaggcctgc ccagcacagg actgcctggt tcagcaataa ccagtgcagg actgcctggt   2220

gcgggaatgc ccagtgcagg aatacctagt gcaggaggtg aagagcatgc cttcctgact   2280

gtaggatcaa aggaagccaa taatgggcct ccatttaact ttcctggtaa ttttggtgga   2340

tcaaatgcct ttgggccacc aatccctcct ccaggattag gaggcggggc ctttggtgat   2400

gctaggcctg gtatgccttc agttggaaac agtggtttgc ctggtctagg actggatgtt   2460

ccgggttttg gaggtggacc aaacaattta agtgggccat cgggatttgg agggggccct   2520

cagaattttg gaaatggccc tggtagctta ggcggtcccc cggggtttgg aagtggccct   2580

cctggtcttg gaagtgcccc tgggcatttg ggtgggccac cagcttttgg gcctggcccc   2640

ggccccggcc ccggccctgg cccaatccat attggtggtc cccctggctt tgcatctagt   2700

tctggaaaac caggaccgac agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt   2760

gatgagattt tagatttctt ttatggctat caagtaatcc caggctcagt gtgtttaaaa   2820

tacaatgaaa aaggtatgcc cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa   2880

gccacagctg ctgtcattga cttaaatgac aggcctatag gttcaagaaa agtaaaactt   2940

gtattagggt agccattcac atcatttttt atagggtaga tcttcatatt gctgtgatta   3000

atgcatccag attgttttcc tagtatttcc aggttagaac ctgtggattg tttcaattgc   3060

atatagcttg gtttccataa catagagcat tggttgactg tttacagaag actcactcac   3120

caggataaac attgctgtat gttacagtaa agctatctgg agagaacaca taaatgattt   3180

tggcatacca ttagagaaac catttgtaaa actcaaatga ccacataaag cttatcaagg   3240

agtctagatt ggttttgttt tataccatat gggatgaaga aaatagaaat gtcagtagaa   3300

ctcattgagg gtgctcttgc cagctgctga aaatagaagt tggctactct cagaatttgg   3360

tttaaagctg gacagatttg ctttgttata gggtaaagct ttgtctaaag tcctcatttt   3420

cttttaaaat tgaataaaat ttctgtatac agattcattg tatgtacctt tattgcttct   3480

taagggtcct tgctgtatag acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt   3540

gactcatttg taaatgagca gaactgtttt gttggttttt ttccctaaat ataaaagtcc   3600

acacttcgtt tgtgctataa cctcaaactt tgatttctaa tgtcacactt aaaactgtgt   3660

ggaataagac ttttgccata aaaataaact atggagtcct ttatctacca gagccttttt   3720

ggtttgaccg ccacgattta ggttagtcag tttaaaaatt gttcatgttg tttggatggt   3780

atcgaaaacc agaaaccact tttaataatg tgtttaagat acttgatttg aagtcctttt   3840

catatggact aattgtagta tcaatttcct cctgtcccga ttatgtgaaa ttttggcctt   3900

taaacaaaga ggggcccatt cataagaaag tgttatatct aggtttttaa aactgaagtt   3960

gaaattatct ttgttagcag tagtagtata gaataaaaga tccgtatgct ggttcgtaga   4020

ttgatacgtg ttagtcctgt tatttggagg ctttttggca tagttgttcg atcaggagcc   4080

tgtttactaa aagtcttcat acagagtaca agtgcagccg ccagaggaga aaattgagat   4140

tcttgaccct ttcatactct tttctttggt attcaggaca ctaaggcagg aggaccacat   4200

gagttctggt tggtaagtgt ccttgtcatg aaaacacttg ccttacaagg ctctaattat   4260

gatttcccta gtcagtgctc tgaagatgtg tcacattata ttataaacaa tacggaaggg   4320

gagataggtg agatgatatg aaaaacaaat tttctcactg tcataaaagg ctctaattat   4380

ggttactttc cttgtgatga aaaacttggc cttacagggc tctagttatg gttactttcc   4440

ctagtcaatg ctctgaaaat gtgtcacatt ataaacaata cagaaggaga gatagatgag   4500

agatcatgaa aaccaaattt tatcttttac atggcccctt tgtcttcgtt tgaaacatcc   4560

ccaacatttc ctacaaatca gcgtagttac aaaggggtca gtcttttaaa ataagtattt   4620

cctattaaac tatatatata tacagtgcct ttttggtgtt gtgagtcagt ggaacactga   4680

aatacagcgg ttgtgtaatt taagagtggc aacagtttca tttgataaga tttgaaaagg   4740

ctttttatca ctacaatctt agaggattga cagtacagga tttttgttta agagaaggat   4800

tgtttagact caagaggtga ctatgttgtg ggtcttttga taattcatga atacagattt   4860

gctttgaccg atcactagat actgcctcct caatttcaaa agcaatataa cgtttgtata   4920

tgctgtttaa tttaagttaa tgttaagtaa tcatttctca ttccaaagac aatgcaaaaa   4980

acttcagcac tgcttgagag ttgtatttca gccacagata ttttctccat tggaaagcta   5040

ttttcatttt agaaaaatgg gttgtttgaa gatgaaagtc ttttatcttt tttcacaatt   5100

tattttggtt atatgttcgt acattcttat taaatatttc atacacttta ttgc         5154


<210>  9762
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9762

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9763
<211>  1326
<212>  DNA
<213>  Homo sapiens

<400>  9763
tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc ccatcaaccc     60

tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa atgatgtcag    120

agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc atgtaggtcg    180

aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg aagctttgaa    240

acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca cagaaagaca    300

gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt ctggacaaac    360

tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga aaagatcaag    420

gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac catttgaagc    480

agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag atagtattta    540

tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt tcagaaatga    600

ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc gctttattca    660

agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc gaaaaagatg    720

tttacagaag actcactcac caggataaac attgctgtat gttacagtaa agctatctgg    780

agagaacaca taaatgattt tggcatacca ttagagaaac catttgtaaa actcaaatga    840

ccacataaag cttatcaagg agtctagatt ggttttgttt tataccatat gggatgaaga    900

aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc cagctgctga aaatagaagt    960

tggctactct cagaatttgg tttaaagctg gacagatttg ctttgttata gggtaaagct   1020

ttgtctaaag tcctcatttt cttttaaaat tgaataaaat ttctgtatac agattcattg   1080

tatgtacctt tattgcttct taagggtcct tgctgtatag acagtcctgc ttcagaagtt   1140

gctgctttgt ttgtctaatt gactcatttg taaatgagca gaactgtttt gttggttttt   1200

ttccctaaat ataaaagtcc acacttcgtt tgtgctataa cctcaaactt tgatttctaa   1260

tgtcacactt aaaactgtgt ggaataagac ttttgccata aaaataaact atggagtcct   1320

ttatct                                                              1326


<210>  9764
<211>  242
<212>  PRT
<213>  Homo sapiens

<400>  9764

Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp 
1               5                   10                  15


Leu Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp 
            20                  25                  30


Val Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu 
        35                  40                  45


Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu 
    50                  55                  60


Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met 
65                  70                  75                  80


Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val 
                85                  90                  95


Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly 
            100                 105                 110


Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser 
        115                 120                 125


Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys 
    130                 135                 140


Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile 
145                 150                 155                 160


Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala 
                165                 170                 175


Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg 
            180                 185                 190


Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met 
        195                 200                 205


Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu 
    210                 215                 220


Glu Lys Ile Asp Met Ile Arg Lys Arg Cys Leu Gln Lys Thr His Ser 
225                 230                 235                 240


Pro Gly 



<210>  9765
<211>  2555
<212>  DNA
<213>  Homo sapiens

<400>  9765
gaatgaatgg ctctggagca cctatgaatt tgaacaataa tctgaatcct atgtttcttg     60

gtccgttgaa tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc    120

ccatcaaccc tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa    180

atgatgtcag agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc    240

atgtaggtcg aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg    300

aagctttgaa acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca    360

cagaaagaca gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt    420

ctggacaaac tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga    480

aaagatcaag gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac    540

catttgaagc agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag    600

atagtattta tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt    660

tcagaaatga ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc    720

gctttattca agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc    780

gaaaaagact gcagaacttc agctatgacc agagggaaat gatactaaat ccagaggggg    840

atgtcaactc tgccaaatta ccctagaaga tatgagagag attgagaaaa atccccctgc    900

ccaaggaaaa aagggattaa agatgcctgt gccaggtaat cctgcagttc caggaatgcc    960

caatgcggga ctgcccggtg tgggactgcc cagtgcagga cttcccggtg caggcctgcc   1020

cagcacagga ctgcctggtt cagcaataac cagtgcagga ctgcctggtg cgggaatgcc   1080

cagtgcagga atacctagtg caggaggtga agagcatgcc ttcctgactg taggatcaaa   1140

ggaagccaat aatgggcctc catttaactt tcctggtaat tttggtggat caaatgcctt   1200

tgggccacca atccctcctc caggattagg aggcggggcc tttggtgatg ctaggcctgg   1260

tatgccttca gttggaaaca gtggtttgcc tggtctagga ctggatgttc cgggttttgg   1320

aggtggacca aacaatttaa gtgggccatc gggatttgga gggggccctc agaattttgg   1380

aaatggccct ggtagcttag gcggtccccc ggggtttgga agtggccctc ctggtcttgg   1440

aagtgcccct gggcatttgg gtgggccacc agcttttggg cctggccccg gccccggccc   1500

cggccctggc ccaatccata ttggtggtcc ccctggcttt gcatctagtt ctggaaaacc   1560

aggaccgaca gtaattaaag tgcaaaacat gccctttact gtgtctattg atgagatttt   1620

agatttcttt tatggctatc aagtaatccc aggctcagtg tgtttaaaat acaatgaaaa   1680

aggtatgccc acaggtgaag ccatggtggc ctttgagtct cgggatgaag ccacagctgc   1740

tgtcattgac ttaaatgaca ggcctatagg ttcaagaaaa gtaaaacttg tattagggta   1800

gccattcaca tcatttttta tagggtagat cttcatattg ctgtgattaa tgcatccaga   1860

ttgttttcct agtatttcca ggttagaacc tgtggattgt ttcaattgca tatagcttgg   1920

tttccataac atagagcatt ggttgactgt ttacagaaga ctcactcacc aggataaaca   1980

ttgctgtatg ttacagtaaa gctatctgga gagaacacat aaatgatttt ggcataccat   2040

tagagaaacc atttgtaaaa ctcaaatgac cacataaagc ttatcaagga gtctagattg   2100

gttttgtttt ataccatatg ggatgaagaa aatagaaatg tcagtagaac tcattgaggg   2160

tgctcttgcc agctgctgaa aatagaagtt ggctactctc agaatttggt ttaaagctgg   2220

acagatttgc tttgttatag ggtaaagctt tgtctaaagt cctcattttc ttttaaaatt   2280

gaataaaatt tctgtataca gattcattgt atgtaccttt attgcttctt aagggtcctt   2340

gctgtataga cagtcctgct tcagaagttg ctgctttgtt tgtctaattg actcatttgt   2400

aaatgagcag aactgttttg ttggtttttt tccctaaata taaaagtcca cacttcgttt   2460

gtgctataac ctcaaacttt gatttctaat gtcacactta aaactgtgtg gaataagact   2520

tttgccataa aaataaacta tggagtcctt tatct                              2555


<210>  9766
<211>  287
<212>  PRT
<213>  Homo sapiens

<400>  9766

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Leu Pro 
        275                 280                 285


<210>  9767
<211>  2726
<212>  DNA
<213>  Homo sapiens

<400>  9767
ttgcctcctg tgcctcctgt gcccccgatt cccccagttc cttctgtgcc acccatgacc     60

ccactgccac ccatgtcggg catgccgccc ttgaatccgc cacctgtggc acctctacct    120

gctggaatga atggctctgg agcacctatg aatttgaaca ataatctgaa tcctatgttt    180

cttggtccgt tgaatcctgt taaccctatc cagatgaact ctcagagcag tgtgaagcca    240

ctccccatca accctgatga tctgtatgtc agtgtgcatg gaatgccctt ttctgcaatg    300

gaaaatgatg tcagagattt ttttcatggg ctccgtgttg atgcagtgca tttgttgaaa    360

gatcatgtag gtcgaaataa tgggaatgga ttggttaagt ttctctcccc tcaagataca    420

tttgaagctt tgaaacgaaa cagaatgctg atgattcaac gctatgtgga agttagccct    480

gccacagaaa gacagtgggt agctgctgga ggccatatca cttttaagca aaatatggga    540

ccttctggac aaactcatcc ccctcctcag acacttccca ggtcaaaatc gcccagtggg    600

cagaaaagat caaggtcaag atcaccacat gaggctggtt tttgtgttta cttgaaaggg    660

ctaccatttg aagcagaaaa caaacatgtc attgattttt ttaaaaagct ggatattgtg    720

gaagatagta tttatatagc ttatggaccc aatgggaaag caactggcga aggctttgta    780

gagttcagaa atgaggctga ctataaggct gctctgtgtc gtcataaaca gtacatgggc    840

aatcgcttta ttcaagttca tccaattact aagaaaggta tgctagaaaa gatagatatg    900

attcgaaaaa gactgcagaa cttcagctat gaccagaggg aaatgatact aaatccagag    960

ggggatgtca actctgccaa agtctgtgcc cacataacaa atattccatt cagcattaca   1020

aagatggatg ttcttcagtt cctagaagga atcccagtgg atgaaaatgc tgtacatgtt   1080

cttgttgata acaatgggca aggtctagga caggcattgg ttcagaatgc ccaatgcggg   1140

actgcccggt gtgggactgc ccagtgcagg acttcccggt gcaggcctgc ccagcacagg   1200

actgcctggt tcagcaataa ccagtgcagg actgcctggt gcgggaatgc ccagtgcagg   1260

aatacctagt gcaggaggtg aagagcatgc cttcctgact gtaggatcaa aggaagccaa   1320

taatgggcct ccatttaact ttcctggtaa ttttggtgga tcaaatgcct ttgggccacc   1380

aatccctcct ccaggattag gaggcggggc ctttggtgat gctaggcctg gtatgccttc   1440

agttggaaac agtggtttgc ctggtctagg actggatgtt ccgggttttg gaggtggacc   1500

aaacaattta agtgggccat cgggatttgg agggggccct cagaattttg gaaatggccc   1560

tggtagctta ggcggtcccc cggggtttgg aagtggccct cctggtcttg gaagtgcccc   1620

tgggcatttg ggtgggccac cagcttttgg gcctggcccc ggccccggcc ccggccctgg   1680

cccaatccat attggtggtc cccctggctt tgcatctagt tctggaaaac caggaccgac   1740

agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt gatgagattt tagatttctt   1800

ttatggctat caagtaatcc caggctcagt gtgtttaaaa tacaatgaaa aaggtatgcc   1860

cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa gccacagctg ctgtcattga   1920

cttaaatgac aggcctatag gttcaagaaa agtaaaactt gtattagggt agccattcac   1980

atcatttttt atagggtaga tcttcatatt gctgtgatta atgcatccag attgttttcc   2040

tagtatttcc aggttagaac ctgtggattg tttcaattgc atatagcttg gtttccataa   2100

catagagcat tggttgactg tttacagaag actcactcac caggataaac attgctgtat   2160

gttacagtaa agctatctgg agagaacaca taaatgattt tggcatacca ttagagaaac   2220

catttgtaaa actcaaatga ccacataaag cttatcaagg agtctagatt ggttttgttt   2280

tataccatat gggatgaaga aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc   2340

cagctgctga aaatagaagt tggctactct cagaatttgg tttaaagctg gacagatttg   2400

ctttgttata gggtaaagct ttgtctaaag tcctcatttt cttttaaaat tgaataaaat   2460

ttctgtatac agattcattg tatgtacctt tattgcttct taagggtcct tgctgtatag   2520

acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt gactcatttg taaatgagca   2580

gaactgtttt gttggttttt ttccctaaat ataaaagtcc acacttcgtt tgtgctataa   2640

cctcaaactt tgatttctaa tgtcacactt aaaactgtgt ggaataagac ttttgccata   2700

aaaataaact atggagtcct ttatct                                        2726


<210>  9768
<211>  404
<212>  PRT
<213>  Homo sapiens

<400>  9768

Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro Pro 
1               5                   10                  15


Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro Met 
            20                  25                  30


Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn Pro 
        35                  40                  45


Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro 
    50                  55                  60


Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe Ser 
65                  70                  75                  80


Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val Asp 
                85                  90                  95


Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly 
            100                 105                 110


Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg 
        115                 120                 125


Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr 
    130                 135                 140


Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn 
145                 150                 155                 160


Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg 
                165                 170                 175


Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His 
            180                 185                 190


Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu 
        195                 200                 205


Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp 
    210                 215                 220


Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly 
225                 230                 235                 240


Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg 
                245                 250                 255


His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr 
            260                 265                 270


Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu Gln 
        275                 280                 285


Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly Asp 
    290                 295                 300


Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe Ser 
305                 310                 315                 320


Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val Asp 
                325                 330                 335


Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu Gly 
            340                 345                 350


Gln Ala Leu Val Gln Asn Ala Gln Cys Gly Thr Ala Arg Cys Gly Thr 
        355                 360                 365


Ala Gln Cys Arg Thr Ser Arg Cys Arg Pro Ala Gln His Arg Thr Ala 
    370                 375                 380


Trp Phe Ser Asn Asn Gln Cys Arg Thr Ala Trp Cys Gly Asn Ala Gln 
385                 390                 395                 400


Cys Arg Asn Thr 



<210>  9769
<211>  3482
<212>  DNA
<213>  Homo sapiens

<400>  9769
caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc cgtttgcaag gtctcccaat     60

tgtggcgggg accatggaca ttcgccactt cttctctgga ttgaccattc ctgatggggg    120

cgtgcatatt gtagggggtg aactgggtga ggctttcatc gtttttgcca ctgatgaaga    180

tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa gggtcaaaag taacactatt    240

gttgagtagt aagacggaaa tgcagaatat gattgaactg agtcgtaggc gttttgaaac    300

tgccaactta gatataccac cagcaaatgc cagtagatca ggaccaccac ctagctcagg    360

aatgagtagc agggtaaact tgcccacaac agtatccaac tttaataatc catcacccag    420

tgtagttact gccaccactt ctgttcatga aagcaacaaa aacatacaga cattttccac    480

agccagcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc caacgtttag    540

ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac caattcctcc    600

aattccagcg atgccatctt ctgtgccacc catgacccca ctgccaccca tgtcgggcat    660

gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg gctctggagc    720

acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga atcctgttaa    780

ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc ctgatgatct    840

gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca gagatttttt    900

tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc gaaataatgg    960

gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga aacgaaacag   1020

aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac agtgggtagc   1080

tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa ctcatccccc   1140

tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc   1200

accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag cagaaaacaa   1260

acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt atatagctta   1320

tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg aggctgacta   1380

taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc aagttcatcc   1440

aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac tgcagaactt   1500

cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact ctgccaaagt   1560

ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc ttcagttcct   1620

agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca atgggcaagg   1680

tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt   1740

acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc tagaagatat   1800

gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc   1860

aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg gactgcccag   1920

tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag caataaccag   1980

tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag gaggtgaaga   2040

gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat ttaactttcc   2100

tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag gattaggagg   2160

cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg   2220

tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg ggccatcggg   2280

atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg gtcccccggg   2340

gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg ggccaccagc   2400

ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg gtggtccccc   2460

tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc aaaacatgcc   2520

ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag taatcccagg   2580

ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt   2640

tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc ctataggttc   2700

aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag ggtagatctt   2760

catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt tagaacctgt   2820

ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt tgactgttta   2880

cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct atctggagag   2940

aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc aaatgaccac   3000

ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga tgaagaaaat   3060

agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat agaagttggc   3120

tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt aaagctttgt   3180

ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat tcattgtatg   3240

tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca gaagttgctg   3300

ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg gtttttttcc   3360

ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat ttctaatgtc   3420

acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg agtcctttat   3480

ct                                                                  3482


<210>  9770
<211>  900
<212>  PRT
<213>  Homo sapiens

<400>  9770

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
        195                 200                 205


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
    210                 215                 220


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
225                 230                 235                 240


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
                245                 250                 255


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
            260                 265                 270


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
        275                 280                 285


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
    290                 295                 300


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
305                 310                 315                 320


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
                325                 330                 335


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
            340                 345                 350


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
        355                 360                 365


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
    370                 375                 380


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
385                 390                 395                 400


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
                405                 410                 415


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
            420                 425                 430


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
        435                 440                 445


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
    450                 455                 460


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
465                 470                 475                 480


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
                485                 490                 495


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
            500                 505                 510


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
        515                 520                 525


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
    530                 535                 540


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
545                 550                 555                 560


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
                565                 570                 575


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
            580                 585                 590


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
        595                 600                 605


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
    610                 615                 620


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
625                 630                 635                 640


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
                645                 650                 655


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
            660                 665                 670


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
        675                 680                 685


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
    690                 695                 700


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
705                 710                 715                 720


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
                725                 730                 735


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
            740                 745                 750


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
        755                 760                 765


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
    770                 775                 780


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
785                 790                 795                 800


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
                805                 810                 815


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
            820                 825                 830


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
        835                 840                 845


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
    850                 855                 860


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
865                 870                 875                 880


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
                885                 890                 895


Leu Val Leu Gly 
            900


<210>  9771
<211>  3744
<212>  DNA
<213>  Homo sapiens

<400>  9771
gaaatgcctc cgaggtccat tgctggggag gggctttact cgagggtgta gcagttttga     60

gaagccggcg tctgaagcta ggagtctaaa agttggtttt aattggttgc ccacaggatt    120

gacttggcct ctacttcttg ttaaggaaat tcatctcttg ttttatcagg tgtgtgtggt    180

ttcagcgcag catggctgtg gtcatccgtt tgcaaggtct cccaattgtg gcggggacca    240

tggacattcg ccacttcttc tctggattga ccattcctga tgggggcgtg catattgtag    300

ggggtgaact gggtgaggct ttcatcgttt ttgccactga tgaagatgca aggcttggta    360

tgatgcgcac aggtggtaca attaaagggt caaaagtaac actattgttg agtagtaaga    420

cggaaatgca gaatatgatt gaactgagtc gtaggcgttt tgaaactgcc aacttagata    480

taccaccagc aaatgccagt agatcaggac caccacctag ctcaggaatg agtagcaggg    540

taaacttgcc cacaacagta tccaacttta ataatccatc acccagtgta gttactgcca    600

ccacttctgt tcatgaaagc aacaaaaaca tacagacatt ttccacagcc agcgtaggaa    660

cagctcctcc aaatatgggg gcttcctttg ggagcccaac gtttagctca actgttccaa    720

gcacagcctc tccaatgaac acagtcccgc cgccaccaat tcctccaatt ccagcgatgc    780

catctctgcc accaatgcca tccattcccc caattccagt tcctcctcca gtacctacat    840

tgcctcctgt gcctcctgtg cccccgattc ccccagttcc ttctgtgcca cccatgaccc    900

cactgccacc catgtcgggc atgccgccct tgaatccgcc acctgtggca cctctacctg    960

ctggaatgaa tggctctgga gcacctatga atttgaacaa taatctgaat cctatgtttc   1020

ttggtccgtt gaatcctgtt aaccctatcc agatgaactc tcagagcagt gtgaagccac   1080

tccccatcaa ccctgatgat ctgtatgtca gtgtgcatgg aatgcccttt tctgcaatgg   1140

aaaatgatgt cagagatttt tttcatgggc tccgtgttga tgcagtgcat ttgttgaaag   1200

atcatgtagg tcgaaataat gggaatggat tggttaagtt tctctcccct caagatacat   1260

ttgaagcttt gaaacgaaac agaatgctga tgattcaacg ctatgtggaa gttagccctg   1320

ccacagaaag acagtgggta gctgctggag gccatatcac ttttaagcaa aatatgggac   1380

cttctggaca aactcatccc cctcctcaga cacttcccag gtcaaaatcg cccagtgggc   1440

agaaaagatc aaggtcaaga tcaccacatg aggctggttt ttgtgtttac ttgaaagggc   1500

taccatttga agcagaaaac aaacatgtca ttgatttttt taaaaagctg gatattgtgg   1560

aagatagtat ttatatagct tatggaccca atgggaaagc aactggcgaa ggctttgtag   1620

agttcagaaa tgaggctgac tataaggctg ctctgtgtcg tcataaacag tacatgggca   1680

atcgctttat tcaagttcat ccaattacta agaaaggtat gctagaaaag atagatatga   1740

ttcgaaaaag actgcagaac ttcagctatg accagaggga aatgatacta aatccagagg   1800

gggatgtcaa ctctgccaaa gtctgtgccc acataacaaa tattccattc agcattacaa   1860

agatggatgt tcttcagttc ctagaaggaa tcccagtgga tgaaaatgct gtacatgttc   1920

ttgttgataa caatgggcaa ggtctaggac aggcattggt tcagtttaaa aatgaagatg   1980

atgcacgtaa gtctgaacgc ttacaccgta aaaaacttaa tgggagagaa gcttttgttc   2040

atgtagttac cctagaagat atgagagaga ttgagaaaaa tccccctgcc caaggaaaaa   2100

agggattaaa gatgcctgtg ccaggtaatc ctgcagttcc aggaatgccc aatgcgggac   2160

tgcccggtgt gggactgccc agtgcaggac ttcccggtgc aggcctgccc agcacaggac   2220

tgcctggttc agcaataacc agtgcaggac tgcctggtgc gggaatgccc agtgcaggaa   2280

tacctagtgc aggaggtgaa gagcatgcct tcctgactgt aggatcaaag gaagccaata   2340

atgggcctcc atttaacttt cctggtaatt ttggtggatc aaatgccttt gggccaccaa   2400

tccctcctcc aggattagga ggcggggcct ttggtgatgc taggcctggt atgccttcag   2460

ttggaaacag tggtttgcct ggtctaggac tggatgttcc gggttttgga ggtggaccaa   2520

acaatttaag tgggccatcg ggatttggag ggggccctca gaattttgga aatggccctg   2580

gtagcttagg cggtcccccg gggtttggaa gtggccctcc tggtcttgga agtgcccctg   2640

ggcatttggg tgggccacca gcttttgggc ctggccccgg ccccggcccc ggccctggcc   2700

caatccatat tggtggtccc cctggctttg catctagttc tggaaaacca ggaccgacag   2760

taattaaagt gcaaaacatg ccctttactg tgtctattga tgagatttta gatttctttt   2820

atggctatca agtaatccca ggctcagtgt gtttaaaata caatgaaaaa ggtatgccca   2880

caggtgaagc catggtggcc tttgagtctc gggatgaagc cacagctgct gtcattgact   2940

taaatgacag gcctataggt tcaagaaaag taaaacttgt attagggtag ccattcacat   3000

cattttttat agggtagatc ttcatattgc tgtgattaat gcatccagat tgttttccta   3060

gtatttccag gttagaacct gtggattgtt tcaattgcat atagcttggt ttccataaca   3120

tagagcattg gttgactgtt tacagaagac tcactcacca ggataaacat tgctgtatgt   3180

tacagtaaag ctatctggag agaacacata aatgattttg gcataccatt agagaaacca   3240

tttgtaaaac tcaaatgacc acataaagct tatcaaggag tctagattgg ttttgtttta   3300

taccatatgg gatgaagaaa atagaaatgt cagtagaact cattgagggt gctcttgcca   3360

gctgctgaaa atagaagttg gctactctca gaatttggtt taaagctgga cagatttgct   3420

ttgttatagg gtaaagcttt gtctaaagtc ctcattttct tttaaaattg aataaaattt   3480

ctgtatacag attcattgta tgtaccttta ttgcttctta agggtccttg ctgtatagac   3540

agtcctgctt cagaagttgc tgctttgttt gtctaattga ctcatttgta aatgagcaga   3600

actgttttgt tggttttttt ccctaaatat aaaagtccac acttcgtttg tgctataacc   3660

tcaaactttg atttctaatg tcacacttaa aactgtgtgg aataagactt ttgccataaa   3720

aataaactat ggagtccttt atct                                          3744


<210>  9772
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9772

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9773
<211>  3337
<212>  DNA
<213>  Homo sapiens

<400>  9773
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg gtttcagcgc    240

accagcgtag gaacagctcc tccaaatatg ggggcttcct ttgggagccc aacgtttagc    300

tcaactgttc caagcacagc ctctccaatg aacacagtcc cgccgccacc aattcctcca    360

attccagcga tgccatctct gccaccaatg ccatccattc ccccaattcc agttcctcct    420

ccagtaccta cattgcctcc tgtgcctcct gtgcccccga ttcccccagt tccttctgtg    480

ccacccatga ccccactgcc acccatgtcg ggcatgccgc ccttgaatcc gccacctgtg    540

gcacctctac ctgctggaat gaatggctct ggagcaccta tgaatttgaa caataatctg    600

aatcctatgt ttcttggtcc gttgaatcct gttaacccta tccagatgaa ctctcagagc    660

agtgtgaagc cactccccat caaccctgat gatctgtatg tcagtgtgca tggaatgccc    720

ttttctgcaa tggaaaatga tgtcagagat ttttttcatg ggctccgtgt tgatgcagtg    780

catttgttga aagatcatgt aggtcgaaat aatgggaatg gattggttaa gtttctctcc    840

cctcaagata catttgaagc tttgaaacga aacagaatgc tgatgattca acgctatgtg    900

gaagttagcc ctgccacaga aagacagtgg gtagctgctg gaggccatat cacttttaag    960

caaaatatgg gaccttctgg acaaactcat ccccctcctc agacacttcc caggtcaaaa   1020

tcgcccagtg ggcagaaaag atcaaggtca agatcaccac atgaggctgg tttttgtgtt   1080

tacttgaaag ggctaccatt tgaagcagaa aacaaacatg tcattgattt ttttaaaaag   1140

ctggatattg tggaagatag tatttatata gcttatggac ccaatgggaa agcaactggc   1200

gaaggctttg tagagttcag aaatgaggct gactataagg ctgctctgtg tcgtcataaa   1260

cagtacatgg gcaatcgctt tattcaagtt catccaatta ctaagaaagg tatgctagaa   1320

aagatagata tgattcgaaa aagactgcag aacttcagct atgaccagag ggaaatgata   1380

ctaaatccag agggggatgt caactctgcc aaagtctgtg cccacataac aaatattcca   1440

ttcagcatta caaagatgga tgttcttcag ttcctagaag gaatcccagt ggatgaaaat   1500

gctgtacatg ttcttgttga taacaatggg caaggtctag gacaggcatt ggttcagttt   1560

aaaaatgaag atgatgcacg taagtctgaa cgcttacacc gtaaaaaact taatgggaga   1620

gaagcttttg ttcatgtagt taccctagaa gatatgagag agattgagaa aaatccccct   1680

gcccaaggaa aaaagggatt aaagatgcct gtgccaggta atcctgcagt tccaggaatg   1740

cccaatgcgg gactgcccgg tgtgggactg cccagtgcag gacttcccgg tgcaggcctg   1800

cccagcacag gactgcctgg ttcagcaata accagtgcag gactgcctgg tgcgggaatg   1860

cccagtgcag gaatacctag tgcaggaggt gaagagcatg ccttcctgac tgtaggatca   1920

aaggaagcca ataatgggcc tccatttaac tttcctggta attttggtgg atcaaatgcc   1980

tttgggccac caatccctcc tccaggatta ggaggcgggg cctttggtga tgctaggcct   2040

ggtatgcctt cagttggaaa cagtggtttg cctggtctag gactggatgt tccgggtttt   2100

ggaggtggac caaacaattt aagtgggcca tcgggatttg gagggggccc tcagaatttt   2160

ggaaatggcc ctggtagctt aggcggtccc ccggggtttg gaagtggccc tcctggtctt   2220

ggaagtgccc ctgggcattt gggtgggcca ccagcttttg ggcctggccc cggccccggc   2280

cccggccctg gcccaatcca tattggtggt ccccctggct ttgcatctag ttctggaaaa   2340

ccaggaccga cagtaattaa agtgcaaaac atgcccttta ctgtgtctat tgatgagatt   2400

ttagatttct tttatggcta tcaagtaatc ccaggctcag tgtgtttaaa atacaatgaa   2460

aaaggtatgc ccacaggtga agccatggtg gcctttgagt ctcgggatga agccacagct   2520

gctgtcattg acttaaatga caggcctata ggttcaagaa aagtaaaact tgtattaggg   2580

tagccattca catcattttt tatagggtag atcttcatat tgctgtgatt aatgcatcca   2640

gattgttttc ctagtatttc caggttagaa cctgtggatt gtttcaattg catatagctt   2700

ggtttccata acatagagca ttggttgact gtttacagaa gactcactca ccaggataaa   2760

cattgctgta tgttacagta aagctatctg gagagaacac ataaatgatt ttggcatacc   2820

attagagaaa ccatttgtaa aactcaaatg accacataaa gcttatcaag gagtctagat   2880

tggttttgtt ttataccata tgggatgaag aaaatagaaa tgtcagtaga actcattgag   2940

ggtgctcttg ccagctgctg aaaatagaag ttggctactc tcagaatttg gtttaaagct   3000

ggacagattt gctttgttat agggtaaagc tttgtctaaa gtcctcattt tcttttaaaa   3060

ttgaataaaa tttctgtata cagattcatt gtatgtacct ttattgcttc ttaagggtcc   3120

ttgctgtata gacagtcctg cttcagaagt tgctgctttg tttgtctaat tgactcattt   3180

gtaaatgagc agaactgttt tgttggtttt tttccctaaa tataaaagtc cacacttcgt   3240

ttgtgctata acctcaaact ttgatttcta atgtcacact taaaactgtg tggaataaga   3300

cttttgccat aaaaataaac tatggagtcc tttatct                            3337


<210>  9774
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9774

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9775
<211>  3653
<212>  DNA
<213>  Homo sapiens

<400>  9775
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

cattcctgat gggggcgtgc atattgtagg gggtgaactg ggtgaggctt tcatcgtttt    240

tgccactgat gaagatgcaa ggcttggtat gatgcgcaca ggtggtacaa ttaaagggtc    300

aaaagtaaca ctattgttga gtagtaagac ggaaatgcag aatatgattg aactgagtcg    360

taggcgtttt gaaactgcca acttagatat accaccagca aatgccagta gatcaggacc    420

accacctagc tcaggaatga gtagcagggt aaacttgccc acaacagtat ccaactttaa    480

taatccatca cccagtgtag ttactgccac cacttctgtt catgaaagca acaaaaacat    540

acagacattt tccacagcca gcgtaggaac agctcctcca aatatggggg cttcctttgg    600

gagcccaacg tttagctcaa ctgttccaag cacagcctct ccaatgaaca cagtcccgcc    660

gccaccaatt cctccaattc cagcgatgcc atctctgcca ccaatgccat ccattccccc    720

aattccagtt cctcctccag tacctacatt gcctcctgtg cctcctgtgc ccccgattcc    780

cccagttcct tctgtgccac ccatgacccc actgccaccc atgtcgggca tgccgccctt    840

gaatccgcca cctgtggcac ctctacctgc tggaatgaat ggctctggag cacctatgaa    900

tttgaacaat aatctgaatc ctatgtttct tggtccgttg aatcctgtta accctatcca    960

gatgaactct cagagcagtg tgaagccact ccccatcaac cctgatgatc tgtatgtcag   1020

tgtgcatgga atgccctttt ctgcaatgga aaatgatgtc agagattttt ttcatgggct   1080

ccgtgttgat gcagtgcatt tgttgaaaga tcatgtaggt cgaaataatg ggaatggatt   1140

ggttaagttt ctctcccctc aagatacatt tgaagctttg aaacgaaaca gaatgctgat   1200

gattcaacgc tatgtggaag ttagccctgc cacagaaaga cagtgggtag ctgctggagg   1260

ccatatcact tttaagcaaa atatgggacc ttctggacaa actcatcccc ctcctcagac   1320

acttcccagg tcaaaatcgc ccagtgggca gaaaagatca aggtcaagat caccacatga   1380

ggctggtttt tgtgtttact tgaaagggct accatttgaa gcagaaaaca aacatgtcat   1440

tgattttttt aaaaagctgg atattgtgga agatagtatt tatatagctt atggacccaa   1500

tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact ataaggctgc   1560

tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc caattactaa   1620

gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact tcagctatga   1680

ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag tctgtgccca   1740

cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc tagaaggaat   1800

cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag gtctaggaca   1860

ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct tacaccgtaa   1920

aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata tgagagagat   1980

tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc caggtaatcc   2040

tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca gtgcaggact   2100

tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca gtgcaggact   2160

gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag agcatgcctt   2220

cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc ctggtaattt   2280

tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag gcggggcctt   2340

tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg gtctaggact   2400

ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg gatttggagg   2460

gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg ggtttggaag   2520

tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag cttttgggcc   2580

tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc ctggctttgc   2640

atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc cctttactgt   2700

gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag gctcagtgtg   2760

tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct ttgagtctcg   2820

ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt caagaaaagt   2880

aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct tcatattgct   2940

gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg tggattgttt   3000

caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt acagaagact   3060

cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga gaacacataa   3120

atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca cataaagctt   3180

atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa tagaaatgtc   3240

agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg ctactctcag   3300

aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg tctaaagtcc   3360

tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat gtacctttat   3420

tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct gctttgtttg   3480

tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc cctaaatata   3540

aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt cacacttaaa   3600

actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta tct          3653


<210>  9776
<211>  876
<212>  PRT
<213>  Homo sapiens

<400>  9776

Met Met Arg Thr Gly Gly Thr Ile Lys Gly Ser Lys Val Thr Leu Leu 
1               5                   10                  15


Leu Ser Ser Lys Thr Glu Met Gln Asn Met Ile Glu Leu Ser Arg Arg 
            20                  25                  30


Arg Phe Glu Thr Ala Asn Leu Asp Ile Pro Pro Ala Asn Ala Ser Arg 
        35                  40                  45


Ser Gly Pro Pro Pro Ser Ser Gly Met Ser Ser Arg Val Asn Leu Pro 
    50                  55                  60


Thr Thr Val Ser Asn Phe Asn Asn Pro Ser Pro Ser Val Val Thr Ala 
65                  70                  75                  80


Thr Thr Ser Val His Glu Ser Asn Lys Asn Ile Gln Thr Phe Ser Thr 
                85                  90                  95


Ala Ser Val Gly Thr Ala Pro Pro Asn Met Gly Ala Ser Phe Gly Ser 
            100                 105                 110


Pro Thr Phe Ser Ser Thr Val Pro Ser Thr Ala Ser Pro Met Asn Thr 
        115                 120                 125


Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro Ser Leu Pro 
    130                 135                 140


Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr 
145                 150                 155                 160


Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val 
                165                 170                 175


Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn 
            180                 185                 190


Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala 
        195                 200                 205


Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu 
    210                 215                 220


Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro 
225                 230                 235                 240


Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro 
                245                 250                 255


Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg 
            260                 265                 270


Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly 
        275                 280                 285


Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu 
    290                 295                 300


Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro 
305                 310                 315                 320


Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys 
                325                 330                 335


Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu 
            340                 345                 350


Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser 
        355                 360                 365


Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu 
    370                 375                 380


Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val 
385                 390                 395                 400


Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly 
                405                 410                 415


Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu 
            420                 425                 430


Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro 
        435                 440                 445


Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg 
    450                 455                 460


Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu 
465                 470                 475                 480


Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro 
                485                 490                 495


Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro 
            500                 505                 510


Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly 
        515                 520                 525


Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys 
    530                 535                 540


Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val 
545                 550                 555                 560


His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro 
                565                 570                 575


Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala 
            580                 585                 590


Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser 
        595                 600                 605


Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser 
    610                 615                 620


Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly 
625                 630                 635                 640


Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser 
                645                 650                 655


Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly 
            660                 665                 670


Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly 
        675                 680                 685


Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser 
    690                 695                 700


Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro 
705                 710                 715                 720


Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe 
                725                 730                 735


Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly 
            740                 745                 750


Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala 
        755                 760                 765


Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile 
    770                 775                 780


Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr 
785                 790                 795                 800


Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile 
                805                 810                 815


Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu 
            820                 825                 830


Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe 
        835                 840                 845


Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg 
    850                 855                 860


Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
865                 870                 875


<210>  9777
<211>  3262
<212>  DNA
<213>  Homo sapiens

<400>  9777
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg tgttccaagc    240

acagcctctc caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca    300

tctctgccac caatgccatc cattccccca attccagttc ctcctccagt acctacattg    360

cctcctgtgc ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca    420

ctgccaccca tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct    480

ggaatgaatg gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt    540

ggtccgttga atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc    600

cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa    660

aatgatgtca gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat    720

catgtaggtc gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt    780

gaagctttga aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc    840

acagaaagac agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct    900

tctggacaaa ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag    960

aaaagatcaa ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta   1020

ccatttgaag cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa   1080

gatagtattt atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag   1140

ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat   1200

cgctttattc aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt   1260

cgaaaaagac tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg   1320

gatgtcaact ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag   1380

atggatgttc ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt   1440

gttgataaca atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat   1500

gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat   1560

gtagttaccc tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag   1620

ggattaaaga tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg   1680

cccggtgtgg gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg   1740

cctggttcag caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata   1800

cctagtgcag gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat   1860

gggcctccat ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc   1920

cctcctccag gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt   1980

ggaaacagtg gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac   2040

aatttaagtg ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt   2100

agcttaggcg gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg   2160

catttgggtg ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca   2220

atccatattg gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta   2280

attaaagtgc aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat   2340

ggctatcaag taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca   2400

ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta   2460

aatgacaggc ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca   2520

ttttttatag ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt   2580

atttccaggt tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata   2640

gagcattggt tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta   2700

cagtaaagct atctggagag aacacataaa tgattttggc ataccattag agaaaccatt   2760

tgtaaaactc aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata   2820

ccatatggga tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc   2880

tgctgaaaat agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt   2940

gttatagggt aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct   3000

gtatacagat tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag   3060

tcctgcttca gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac   3120

tgttttgttg gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc   3180

aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa   3240

taaactatgg agtcctttat ct                                            3262


<210>  9778
<211>  751
<212>  PRT
<213>  Homo sapiens

<400>  9778

Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro 
1               5                   10                  15


Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro 
            20                  25                  30


Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val 
        35                  40                  45


Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro 
    50                  55                  60


Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly 
65                  70                  75                  80


Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu 
                85                  90                  95


Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser 
            100                 105                 110


Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His 
        115                 120                 125


Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His 
    130                 135                 140


Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg 
145                 150                 155                 160


Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe 
                165                 170                 175


Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu 
            180                 185                 190


Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile 
        195                 200                 205


Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro 
    210                 215                 220


Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg 
225                 230                 235                 240


Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu 
                245                 250                 255


Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu 
            260                 265                 270


Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys 
        275                 280                 285


Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys 
    290                 295                 300


Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln 
305                 310                 315                 320


Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile 
                325                 330                 335


Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu 
            340                 345                 350


Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr 
        355                 360                 365


Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu 
    370                 375                 380


Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn 
385                 390                 395                 400


Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp 
                405                 410                 415


Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu 
            420                 425                 430


Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys 
        435                 440                 445


Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly 
    450                 455                 460


Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly 
465                 470                 475                 480


Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu 
                485                 490                 495


Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro 
            500                 505                 510


Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr 
        515                 520                 525


Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly 
    530                 535                 540


Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly 
545                 550                 555                 560


Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val 
                565                 570                 575


Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly 
            580                 585                 590


Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro 
        595                 600                 605


Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe 
    610                 615                 620


Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly 
625                 630                 635                 640


Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
                645                 650                 655


Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro 
            660                 665                 670


Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile 
        675                 680                 685


Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser 
    690                 695                 700


Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met 
705                 710                 715                 720


Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu 
                725                 730                 735


Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
            740                 745                 750


<210>  9779
<211>  3228
<212>  DNA
<213>  Homo sapiens

<400>  9779
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc    180

caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac    240

caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt cccccaattc    300

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    360

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    420

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    480

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    540

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    600

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    660

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    720

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    780

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    840

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    900

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    960

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt   1020

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1080

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1140

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1200

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1260

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1320

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1380

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1440

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1500

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1560

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1620

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1680

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1740

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1800

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1860

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1920

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1980

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   2040

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2100

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2160

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2220

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2280

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2340

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2400

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2460

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2520

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2580

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2640

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2700

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2760

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2820

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2880

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2940

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   3000

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3060

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3120

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3180

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatct                3228


<210>  9780
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9780

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9781
<211>  3168
<212>  DNA
<213>  Homo sapiens

<400>  9781
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatcttc tgccaccaat gccatccatt cccccaattc    240

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    300

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    360

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    420

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    480

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    540

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    600

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    660

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    720

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    780

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    840

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    900

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt    960

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1020

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1080

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1140

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1200

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1260

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1320

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1380

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1440

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1500

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1560

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1620

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1680

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1740

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1800

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1860

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1920

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   1980

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2040

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2100

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2160

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2220

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2280

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2340

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2400

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2460

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2520

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2580

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2640

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2700

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2760

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2820

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2880

ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc tttattgctt   2940

cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt gtttgtctaa   3000

ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa atataaaagt   3060

ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac ttaaaactgt   3120

gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatct                3168


<210>  9782
<211>  731
<212>  PRT
<213>  Homo sapiens

<400>  9782

Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr Leu 
1               5                   10                  15


Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val Pro 
            20                  25                  30


Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro 
        35                  40                  45


Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro 
    50                  55                  60


Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn 
65                  70                  75                  80


Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu 
                85                  90                  95


Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe 
            100                 105                 110


Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val 
        115                 120                 125


Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn 
    130                 135                 140


Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys 
145                 150                 155                 160


Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala 
                165                 170                 175


Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln 
            180                 185                 190


Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro 
        195                 200                 205


Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro 
    210                 215                 220


His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala 
225                 230                 235                 240


Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu 
                245                 250                 255


Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu 
            260                 265                 270


Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys 
        275                 280                 285


Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile 
    290                 295                 300


Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu 
305                 310                 315                 320


Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly 
                325                 330                 335


Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe 
            340                 345                 350


Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val 
        355                 360                 365


Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu 
    370                 375                 380


Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys Ser 
385                 390                 395                 400


Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val His 
                405                 410                 415


Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro Ala 
            420                 425                 430


Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala Val 
        435                 440                 445


Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser Ala 
    450                 455                 460


Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser Ala 
465                 470                 475                 480


Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly Ile 
                485                 490                 495


Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser Lys 
            500                 505                 510


Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly Gly 
        515                 520                 525


Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly Gly 
    530                 535                 540


Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser Gly 
545                 550                 555                 560


Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro Asn 
                565                 570                 575


Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe Gly 
            580                 585                 590


Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly Pro 
        595                 600                 605


Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala Phe 
    610                 615                 620


Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile Gly 
625                 630                 635                 640


Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr Val 
                645                 650                 655


Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile Leu 
            660                 665                 670


Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu Lys 
        675                 680                 685


Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe Glu 
    690                 695                 700


Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg Pro 
705                 710                 715                 720


Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
                725                 730


<210>  9783
<211>  3720
<212>  DNA
<213>  Homo sapiens

<400>  9783
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccggtgtg tgtggtttca gcgcagcatg gctgtggtca    180

tccgtttgca aggtctccca attgtggcgg ggaccatgga cattcgccac ttcttctctg    240

gattgaccat tcctgatggg ggcgtgcata ttgtaggggg tgaactgggt gaggctttca    300

tcgtttttgc cactgatgaa gatgcaaggc ttggtatgat gcgcacaggt ggtacaatta    360

aagggtcaaa agtaacacta ttgttgagta gtaagacgga aatgcagaat atgattgaac    420

tgagtcgtag gcgttttgaa actgccaact tagatatacc accagcaaat gccagtagat    480

caggaccacc acctagctca ggaatgagta gcagggtaaa cttgcccaca acagtatcca    540

actttaataa tccatcaccc agtgtagtta ctgccaccac ttctgttcat gaaagcaaca    600

aaaacataca gacattttcc acagccagcg taggaacagc tcctccaaat atgggggctt    660

cctttgggag cccaacgttt agctcaactg ttccaagcac agcctctcca atgaacacag    720

tcccgccgcc accaattcct ccaattccag cgatgccatc tctgccacca atgccatcca    780

ttcccccaat tccagttcct cctccagtac ctacattgcc tcctgtgcct cctgtgcccc    840

cgattccccc agttccttct gtgccaccca tgaccccact gccacccatg tcgggcatgc    900

cgcccttgaa tccgccacct gtggcacctc tacctgctgg aatgaatggc tctggagcac    960

ctatgaattt gaacaataat ctgaatccta tgtttcttgg tccgttgaat cctgttaacc   1020

ctatccagat gaactctcag agcagtgtga agccactccc catcaaccct gatgatctgt   1080

atgtcagtgt gcatggaatg cccttttctg caatggaaaa tgatgtcaga gatttttttc   1140

atgggctccg tgttgatgca gtgcatttgt tgaaagatca tgtaggtcga aataatggga   1200

atggattggt taagtttctc tcccctcaag atacatttga agctttgaaa cgaaacagaa   1260

tgctgatgat tcaacgctat gtggaagtta gccctgccac agaaagacag tgggtagctg   1320

ctggaggcca tatcactttt aagcaaaata tgggaccttc tggacaaact catccccctc   1380

ctcagacact tcccaggtca aaatcgccca gtgggcagaa aagatcaagg tcaagatcac   1440

cacatgaggc tggtttttgt gtttacttga aagggctacc atttgaagca gaaaacaaac   1500

atgtcattga tttttttaaa aagctggata ttgtggaaga tagtatttat atagcttatg   1560

gacccaatgg gaaagcaact ggcgaaggct ttgtagagtt cagaaatgag gctgactata   1620

aggctgctct gtgtcgtcat aaacagtaca tgggcaatcg ctttattcaa gttcatccaa   1680

ttactaagaa aggtatgcta gaaaagatag atatgattcg aaaaagactg cagaacttca   1740

gctatgacca gagggaaatg atactaaatc cagaggggga tgtcaactct gccaaagtct   1800

gtgcccacat aacaaatatt ccattcagca ttacaaagat ggatgttctt cagttcctag   1860

aaggaatccc agtggatgaa aatgctgtac atgttcttgt tgataacaat gggcaaggtc   1920

taggacaggc attggttcag tttaaaaatg aagatgatgc acgtaagtct gaacgcttac   1980

accgtaaaaa acttaatggg agagaagctt ttgttcatgt agttacccta gaagatatga   2040

gagagattga gaaaaatccc cctgcccaag gaaaaaaggg attaaagatg cctgtgccag   2100

gtaatcctgc agttccagga atgcccaatg cgggactgcc cggtgtggga ctgcccagtg   2160

caggacttcc cggtgcaggc ctgcccagca caggactgcc tggttcagca ataaccagtg   2220

caggactgcc tggtgcggga atgcccagtg caggaatacc tagtgcagga ggtgaagagc   2280

atgccttcct gactgtagga tcaaaggaag ccaataatgg gcctccattt aactttcctg   2340

gtaattttgg tggatcaaat gcctttgggc caccaatccc tcctccagga ttaggaggcg   2400

gggcctttgg tgatgctagg cctggtatgc cttcagttgg aaacagtggt ttgcctggtc   2460

taggactgga tgttccgggt tttggaggtg gaccaaacaa tttaagtggg ccatcgggat   2520

ttggaggggg ccctcagaat tttggaaatg gccctggtag cttaggcggt cccccggggt   2580

ttggaagtgg ccctcctggt cttggaagtg cccctgggca tttgggtggg ccaccagctt   2640

ttgggcctgg ccccggcccc ggccccggcc ctggcccaat ccatattggt ggtccccctg   2700

gctttgcatc tagttctgga aaaccaggac cgacagtaat taaagtgcaa aacatgccct   2760

ttactgtgtc tattgatgag attttagatt tcttttatgg ctatcaagta atcccaggct   2820

cagtgtgttt aaaatacaat gaaaaaggta tgcccacagg tgaagccatg gtggcctttg   2880

agtctcggga tgaagccaca gctgctgtca ttgacttaaa tgacaggcct ataggttcaa   2940

gaaaagtaaa acttgtatta gggtagccat tcacatcatt ttttataggg tagatcttca   3000

tattgctgtg attaatgcat ccagattgtt ttcctagtat ttccaggtta gaacctgtgg   3060

attgtttcaa ttgcatatag cttggtttcc ataacataga gcattggttg actgtttaca   3120

gaagactcac tcaccaggat aaacattgct gtatgttaca gtaaagctat ctggagagaa   3180

cacataaatg attttggcat accattagag aaaccatttg taaaactcaa atgaccacat   3240

aaagcttatc aaggagtcta gattggtttt gttttatacc atatgggatg aagaaaatag   3300

aaatgtcagt agaactcatt gagggtgctc ttgccagctg ctgaaaatag aagttggcta   3360

ctctcagaat ttggtttaaa gctggacaga tttgctttgt tatagggtaa agctttgtct   3420

aaagtcctca ttttctttta aaattgaata aaatttctgt atacagattc attgtatgta   3480

cctttattgc ttcttaaggg tccttgctgt atagacagtc ctgcttcaga agttgctgct   3540

ttgtttgtct aattgactca tttgtaaatg agcagaactg ttttgttggt ttttttccct   3600

aaatataaaa gtccacactt cgtttgtgct ataacctcaa actttgattt ctaatgtcac   3660

acttaaaact gtgtggaata agacttttgc cataaaaata aactatggag tcctttatct   3720


<210>  9784
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9784

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9785
<211>  2982
<212>  DNA
<213>  Homo sapiens

<400>  9785
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccgtctaa aagttggttt taattggttg cccacaggat    180

tgacttggcc tctacctgct ggaatgaatg gctctggagc acctatgaat ttgaacaata    240

atctgaatcc tatgtttctt ggtccgttga atcctgttaa ccctatccag atgaactctc    300

agagcagtgt gaagccactc cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa    360

tgcccttttc tgcaatggaa aatgatgtca gagatttttt tcatgggctc cgtgttgatg    420

cagtgcattt gttgaaagat catgtaggtc gaaataatgg gaatggattg gttaagtttc    480

tctcccctca agatacattt gaagctttga aacgaaacag aatgctgatg attcaacgct    540

atgtggaagt tagccctgcc acagaaagac agtgggtagc tgctggaggc catatcactt    600

ttaagcaaaa tatgggacct tctggacaaa ctcatccccc tcctcagaca cttcccaggt    660

caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc accacatgag gctggttttt    720

gtgtttactt gaaagggcta ccatttgaag cagaaaacaa acatgtcatt gattttttta    780

aaaagctgga tattgtggaa gatagtattt atatagctta tggacccaat gggaaagcaa    840

ctggcgaagg ctttgtagag ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc    900

ataaacagta catgggcaat cgctttattc aagttcatcc aattactaag aaaggtatgc    960

tagaaaagat agatatgatt cgaaaaagac tgcagaactt cagctatgac cagagggaaa   1020

tgatactaaa tccagagggg gatgtcaact ctgccaaagt ctgtgcccac ataacaaata   1080

ttccattcag cattacaaag atggatgttc ttcagttcct agaaggaatc ccagtggatg   1140

aaaatgctgt acatgttctt gttgataaca atgggcaagg tctaggacag gcattggttc   1200

agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg   1260

ggagagaagc ttttgttcat gtagttaccc tagaagatat gagagagatt gagaaaaatc   1320

cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc aggtaatcct gcagttccag   1380

gaatgcccaa tgcgggactg cccggtgtgg gactgcccag tgcaggactt cccggtgcag   1440

gcctgcccag cacaggactg cctggttcag caataaccag tgcaggactg cctggtgcgg   1500

gaatgcccag tgcaggaata cctagtgcag gaggtgaaga gcatgccttc ctgactgtag   1560

gatcaaagga agccaataat gggcctccat ttaactttcc tggtaatttt ggtggatcaa   1620

atgcctttgg gccaccaatc cctcctccag gattaggagg cggggccttt ggtgatgcta   1680

ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg tctaggactg gatgttccgg   1740

gttttggagg tggaccaaac aatttaagtg ggccatcggg atttggaggg ggccctcaga   1800

attttggaaa tggccctggt agcttaggcg gtcccccggg gtttggaagt ggccctcctg   1860

gtcttggaag tgcccctggg catttgggtg ggccaccagc ttttgggcct ggccccggcc   1920

ccggccccgg ccctggccca atccatattg gtggtccccc tggctttgca tctagttctg   1980

gaaaaccagg accgacagta attaaagtgc aaaacatgcc ctttactgtg tctattgatg   2040

agattttaga tttcttttat ggctatcaag taatcccagg ctcagtgtgt ttaaaataca   2100

atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca   2160

cagctgctgt cattgactta aatgacaggc ctataggttc aagaaaagta aaacttgtat   2220

tagggtagcc attcacatca ttttttatag ggtagatctt catattgctg tgattaatgc   2280

atccagattg ttttcctagt atttccaggt tagaacctgt ggattgtttc aattgcatat   2340

agcttggttt ccataacata gagcattggt tgactgttta cagaagactc actcaccagg   2400

ataaacattg ctgtatgtta cagtaaagct atctggagag aacacataaa tgattttggc   2460

ataccattag agaaaccatt tgtaaaactc aaatgaccac ataaagctta tcaaggagtc   2520

tagattggtt ttgttttata ccatatggga tgaagaaaat agaaatgtca gtagaactca   2580

ttgagggtgc tcttgccagc tgctgaaaat agaagttggc tactctcaga atttggttta   2640

aagctggaca gatttgcttt gttatagggt aaagctttgt ctaaagtcct cattttcttt   2700

taaaattgaa taaaatttct gtatacagat tcattgtatg tacctttatt gcttcttaag   2760

ggtccttgct gtatagacag tcctgcttca gaagttgctg ctttgtttgt ctaattgact   2820

catttgtaaa tgagcagaac tgttttgttg gtttttttcc ctaaatataa aagtccacac   2880

ttcgtttgtg ctataacctc aaactttgat ttctaatgtc acacttaaaa ctgtgtggaa   2940

taagactttt gccataaaaa taaactatgg agtcctttat ct                      2982


<210>  9786
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  9786

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala 
        275                 280                 285


His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln 
    290                 295                 300


Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val 
305                 310                 315                 320


Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn 
                325                 330                 335


Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn 
            340                 345                 350


Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu 
        355                 360                 365


Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro 
    370                 375                 380


Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro 
385                 390                 395                 400


Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser 
                405                 410                 415


Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala 
            420                 425                 430


Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala 
        435                 440                 445


Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn 
    450                 455                 460


Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro 
465                 470                 475                 480


Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met 
                485                 490                 495


Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro 
            500                 505                 510


Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly 
        515                 520                 525


Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro 
    530                 535                 540


Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His 
545                 550                 555                 560


Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly 
                565                 570                 575


Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser 
            580                 585                 590


Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr 
        595                 600                 605


Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile 
    610                 615                 620


Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly 
625                 630                 635                 640


Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val 
                645                 650                 655


Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val 
            660                 665                 670


Leu Gly 



<210>  9787
<211>  2703
<212>  DNA
<213>  Homo sapiens

<400>  9787
ggaacgcgga gccgctgagc gggccgacgg ccattttgtg aagcggcgaa ggaggtggtg     60

gctgcgttgg gctccgggaa gccgttcggg ctggggctgt cggccgcggg gcggaggcac    120

tcgcgcgggg gtctaaaagt tggttttaat tggttgccca caggattgac ttggcctcta    180

cttcttgtta aggaaattca tctcttgttt tatcaggtgt gtgtggtttc agcgcagcat    240

ggctgtggtc atccgtttgc aaggtctccc aattgtggcg gggaccatgg acattcgcca    300

cttcttctct ggattgacca ttcctgatgg gggcgtgcat attgtagggg gtgaactggg    360

tgaggctttc atcgtttttg ccactgatga agatgcaagg cttggtatga tgcgcacagg    420

tggtacaatt aaagggtcaa aagtaacact attgttgagt agtaagacgg aaatgcagaa    480

tatgattgaa ctgatttttt aaaaagctgg atattgtgga agatagtatt tatatagctt    540

atggacccaa tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact    600

ataaggctgc tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc    660

caattactaa gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact    720

tcagctatga ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag    780

tctgtgccca cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc    840

tagaaggaat cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag    900

gtctaggaca ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct    960

tacaccgtaa aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata   1020

tgagagagat tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc   1080

caggtaatcc tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca   1140

gtgcaggact tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca   1200

gtgcaggact gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag   1260

agcatgcctt cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc   1320

ctggtaattt tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag   1380

gcggggcctt tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg   1440

gtctaggact ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg   1500

gatttggagg gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg   1560

ggtttggaag tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag   1620

cttttgggcc tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc   1680

ctggctttgc atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc   1740

cctttactgt gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag   1800

gctcagtgtg tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct   1860

ttgagtctcg ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt   1920

caagaaaagt aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct   1980

tcatattgct gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg   2040

tggattgttt caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt   2100

acagaagact cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga   2160

gaacacataa atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca   2220

cataaagctt atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa   2280

tagaaatgtc agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg   2340

ctactctcag aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg   2400

tctaaagtcc tcattttctt ttaaaattga ataaaatttc tgtatacaga ttcattgtat   2460

gtacctttat tgcttcttaa gggtccttgc tgtatagaca gtcctgcttc agaagttgct   2520

gctttgtttg tctaattgac tcatttgtaa atgagcagaa ctgttttgtt ggtttttttc   2580

cctaaatata aaagtccaca cttcgtttgt gctataacct caaactttga tttctaatgt   2640

cacacttaaa actgtgtgga ataagacttt tgccataaaa ataaactatg gagtccttta   2700

tct                                                                 2703


<210>  9788
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9788

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ile Phe 
                85


<210>  9789
<211>  3792
<212>  DNA
<213>  Homo sapiens

<400>  9789
tggaacgcgg agccgctgag cgggccgacg gccattttgt gaagcggcga aggaggtggt     60

ggctgcgttg ggctccggga agccgttcgg gctggggctg tcggccgcgg ggcggaggca    120

ctcgcgcggg ggtctaaaag ttggttttaa ttggttgccc acaggattga cttggcctct    180

acttcttgtt aaggaaattc atctcttgtt ttatcaggtg tgtgtggttt cagcgcagca    240

tggctgtggt catccgtttg caaggtctcc caattgtggc ggggaccatg gacattcgcc    300

acttcttctc tggattgacc attcctgatg ggggcgtgca tattgtaggg ggtgaactgg    360

gtgaggcttt catcgttttt gccactgatg aagatgcaag gcttggtatg atgcgcacag    420

gtggtacaat taaagggtca aaagtaacac tattgttgag tagtaagacg gaaatgcaga    480

atatgattga actgagtcgt aggcgttttg aaactgccaa cttagatata ccaccagcaa    540

atgccagtag atcaggacca ccacctagct caggaatgag tagcagggta aacttgccca    600

caacagtatc caactttaat aatccatcac ccagtgtagt tactgccacc acttctgttc    660

atgaaagcaa caaaaacata cagacatttt ccacagccag cgtaggaaca gctcctccaa    720

atatgggggc ttcctttggg agcccaacgt ttagctcaac tgttccaagc acagcctctc    780

caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca tctctgccac    840

caatgccatc cattccccca attccagttc ctcctccagt acctacattg cctcctgtgc    900

ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca ctgccaccca    960

tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg   1020

gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga   1080

atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc   1140

ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca   1200

gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc   1260

gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga   1320

aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac   1380

agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa   1440

ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa   1500

ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag   1560

cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt   1620

atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg   1680

aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc   1740

aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac   1800

tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact   1860

ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc   1920

ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca   1980

atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt   2040

ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc   2100

tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga   2160

tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg   2220

gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag   2280

caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag   2340

gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat   2400

ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag   2460

gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg   2520

gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg   2580

ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg   2640

gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg   2700

ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg   2760

gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc   2820

aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag   2880

taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca   2940

tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc   3000

ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag   3060

ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt   3120

tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt   3180

tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct   3240

atctggagag aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc   3300

aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga   3360

tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat   3420

agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt   3480

aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat   3540

tcattgtatg tacctttatt gcttcttaag ggtccttgct gtatagacag tcctgcttca   3600

gaagttgctg ctttgtttgt ctaattgact catttgtaaa tgagcagaac tgttttgttg   3660

gtttttttcc ctaaatataa aagtccacac ttcgtttgtg ctataacctc aaactttgat   3720

ttctaatgtc acacttaaaa ctgtgtggaa taagactttt gccataaaaa taaactatgg   3780

agtcctttat ct                                                       3792


<210>  9790
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9790

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9791
<211>  3838
<212>  DNA
<213>  Homo sapiens

<400>  9791
cttctggaac gcggagccgc tgagcgggcc gacggccatt ttgtgaagcg gcgaaggagg     60

tggtggctgc gttgggctcc gggaagccgt tcgggctggg gctgtcggcc gcggggcgga    120

ggcactcgcg cggggggtaa ttcggggtct gggttctggt gccgcgcagc tttccccgtc    180

taaaagttgg ttttaattgg ttgcccacag gattgacttg gcctctactt cttgttaagg    240

aaattcatct cttgttttat caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc    300

cgtttgcaag gtctcccaat tgtggcgggg accatggaca ttcgccactt cttctctgga    360

ttgaccattc ctgatggggg cgtgcatatt gtagggggtg aactgggtga ggctttcatc    420

gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa    480

gggtcaaaag taacactatt gttgagtagt aagacggaaa tgcagaatat gattgaactg    540

agtcgtaggc gttttgaaac tgccaactta gatataccac cagcaaatgc cagtagatca    600

ggaccaccac ctagctcagg aatgagtagc agggtaaact tgcccacaac agtatccaac    660

tttaataatc catcacccag tgtagttact gccaccactt ctgttcatga aagcaacaaa    720

aacatacaga cattttccac agccagcgta ggaacagctc ctccaaatat gggggcttcc    780

tttgggagcc caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc    840

ccgccgccac caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt    900

cccccaattc cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg    960

attcccccag ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg   1020

cccttgaatc cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct   1080

atgaatttga acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct   1140

atccagatga actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat   1200

gtcagtgtgc atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat   1260

gggctccgtg ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat   1320

ggattggtta agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg   1380

ctgatgattc aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct   1440

ggaggccata tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct   1500

cagacacttc ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca   1560

catgaggctg gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat   1620

gtcattgatt tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga   1680

cccaatggga aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag   1740

gctgctctgt gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt   1800

actaagaaag gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc   1860

tatgaccaga gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt   1920

gcccacataa caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa   1980

ggaatcccag tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta   2040

ggacaggcat tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac   2100

cgtaaaaaac ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga   2160

gagattgaga aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt   2220

aatcctgcag ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca   2280

ggacttcccg gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca   2340

ggactgcctg gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat   2400

gccttcctga ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt   2460

aattttggtg gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg   2520

gcctttggtg atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta   2580

ggactggatg ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt   2640

ggagggggcc ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt   2700

ggaagtggcc ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt   2760

gggcctggcc ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc   2820

tttgcatcta gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt   2880

actgtgtcta ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca   2940

gtgtgtttaa aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag   3000

tctcgggatg aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga   3060

aaagtaaaac ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata   3120

ttgctgtgat taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat   3180

tgtttcaatt gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga   3240

agactcactc accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca   3300

cataaatgat tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa   3360

agcttatcaa ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa   3420

atgtcagtag aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact   3480

ctcagaattt ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa   3540

agtcctcatt ttcttttaaa attgaataaa atttctgtat acagattcat tgtatgtacc   3600

tttattgctt cttaagggtc cttgctgtat agacagtcct gcttcagaag ttgctgcttt   3660

gtttgtctaa ttgactcatt tgtaaatgag cagaactgtt ttgttggttt ttttccctaa   3720

atataaaagt ccacacttcg tttgtgctat aacctcaaac tttgatttct aatgtcacac   3780

ttaaaactgt gtggaataag acttttgcca taaaaataaa ctatggagtc ctttatct     3838


<210>  9792
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9792

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9793
<211>  3706
<212>  DNA
<213>  Homo sapiens

<400>  9793
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggagga ttgacttggc ctctacttct tgttaaggaa attcatctct    120

tgttttatca ggtgtgtgtg gtttcagcgc agcatggctg tggtcatccg tttgcaaggt    180

ctcccaattg tggcggggac catggacatt cgccacttct tctctggatt gaccattcct    240

gatgggggcg tgcatattgt agggggtgaa ctgggtgagg ctttcatcgt ttttgccact    300

gatgaagatg caaggcttgg tatgatgcgc acaggtggta caattaaagg gtcaaaagta    360

acactattgt tgagtagtaa gacggaaatg cagaatatga ttgaactgag tcgtaggcgt    420

tttgaaactg ccaacttaga tataccacca gcaaatgcca gtagatcagg accaccacct    480

agctcaggaa tgagtagcag ggtaaacttg cccacaacag tatccaactt taataatcca    540

tcacccagtg tagttactgc caccacttct gttcatgaaa gcaacaaaaa catacagaca    600

ttttccacag ccagcgtagg aacagctcct ccaaatatgg gggcttcctt tgggagccca    660

acgtttagct caactgttcc aagcacagcc tctccaatga acacagtccc gccgccacca    720

attcctccaa ttccagcgat gccatctctg ccaccaatgc catccattcc cccaattcca    780

gttcctcctc cagtacctac attgcctcct gtgcctcctg tgcccccgat tcccccagtt    840

ccttctgtgc cacccatgac cccactgcca cccatgtcgg gcatgccgcc cttgaatccg    900

ccacctgtgg cacctctacc tgctggaatg aatggctctg gagcacctat gaatttgaac    960

aataatctga atcctatgtt tcttggtccg ttgaatcctg ttaaccctat ccagatgaac   1020

tctcagagca gtgtgaagcc actccccatc aaccctgatg atctgtatgt cagtgtgcat   1080

ggaatgccct tttctgcaat ggaaaatgat gtcagagatt tttttcatgg gctccgtgtt   1140

gatgcagtgc atttgttgaa agatcatgta ggtcgaaata atgggaatgg attggttaag   1200

tttctctccc ctcaagatac atttgaagct ttgaaacgaa acagaatgct gatgattcaa   1260

cgctatgtgg aagttagccc tgccacagaa agacagtggg tagctgctgg aggccatatc   1320

acttttaagc aaaatatggg accttctgga caaactcatc cccctcctca gacacttccc   1380

aggtcaaaat cgcccagtgg gcagaaaaga tcaaggtcaa gatcaccaca tgaggctggt   1440

ttttgtgttt acttgaaagg gctaccattt gaagcagaaa acaaacatgt cattgatttt   1500

tttaaaaagc tggatattgt ggaagatagt atttatatag cttatggacc caatgggaaa   1560

gcaactggcg aaggctttgt agagttcaga aatgaggctg actataaggc tgctctgtgt   1620

cgtcataaac agtacatggg caatcgcttt attcaagttc atccaattac taagaaaggt   1680

atgctagaaa agatagatat gattcgaaaa agactgcaga acttcagcta tgaccagagg   1740

gaaatgatac taaatccaga gggggatgtc aactctgcca aagtctgtgc ccacataaca   1800

aatattccat tcagcattac aaagatggat gttcttcagt tcctagaagg aatcccagtg   1860

gatgaaaatg ctgtacatgt tcttgttgat aacaatgggc aaggtctagg acaggcattg   1920

gttcagttta aaaatgaaga tgatgcacgt aagtctgaac gcttacaccg taaaaaactt   1980

aatgggagag aagcttttgt tcatgtagtt accctagaag atatgagaga gattgagaaa   2040

aatccccctg cccaaggaaa aaagggatta aagatgcctg tgccaggtaa tcctgcagtt   2100

ccaggaatgc ccaatgcggg actgcccggt gtgggactgc ccagtgcagg acttcccggt   2160

gcaggcctgc ccagcacagg actgcctggt tcagcaataa ccagtgcagg actgcctggt   2220

gcgggaatgc ccagtgcagg aatacctagt gcaggaggtg aagagcatgc cttcctgact   2280

gtaggatcaa aggaagccaa taatgggcct ccatttaact ttcctggtaa ttttggtgga   2340

tcaaatgcct ttgggccacc aatccctcct ccaggattag gaggcggggc ctttggtgat   2400

gctaggcctg gtatgccttc agttggaaac agtggtttgc ctggtctagg actggatgtt   2460

ccgggttttg gaggtggacc aaacaattta agtgggccat cgggatttgg agggggccct   2520

cagaattttg gaaatggccc tggtagctta ggcggtcccc cggggtttgg aagtggccct   2580

cctggtcttg gaagtgcccc tgggcatttg ggtgggccac cagcttttgg gcctggcccc   2640

ggccccggcc ccggccctgg cccaatccat attggtggtc cccctggctt tgcatctagt   2700

tctggaaaac caggaccgac agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt   2760

gatgagattt tagatttctt ttatggctat caagtaatcc caggctcagt gtgtttaaaa   2820

tacaatgaaa aaggtatgcc cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa   2880

gccacagctg ctgtcattga cttaaatgac aggcctatag gttcaagaaa agtaaaactt   2940

gtattagggt agccattcac atcatttttt atagggtaga tcttcatatt gctgtgatta   3000

atgcatccag attgttttcc tagtatttcc aggttagaac ctgtggattg tttcaattgc   3060

atatagcttg gtttccataa catagagcat tggttgactg tttacagaag actcactcac   3120

caggataaac attgctgtat gttacagtaa agctatctgg agagaacaca taaatgattt   3180

tggcatacca ttagagaaac catttgtaaa actcaaatga ccacataaag cttatcaagg   3240

agtctagatt ggttttgttt tataccatat gggatgaaga aaatagaaat gtcagtagaa   3300

ctcattgagg gtgctcttgc cagctgctga aaatagaagt tggctactct cagaatttgg   3360

tttaaagctg gacagatttg ctttgttata gggtaaagct ttgtctaaag tcctcatttt   3420

cttttaaaat tgaataaaat ttctgtatac agattcattg tatgtacctt tattgcttct   3480

taagggtcct tgctgtatag acagtcctgc ttcagaagtt gctgctttgt ttgtctaatt   3540

gactcatttg taaatgagca gaactgtttt gttggttttt ttccctaaat ataaaagtcc   3600

acacttcgtt tgtgctataa cctcaaactt tgatttctaa tgtcacactt aaaactgtgt   3660

ggaataagac ttttgccata aaaataaact atggagtcct ttatct                  3706


<210>  9794
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9794

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9795
<211>  2305
<212>  DNA
<213>  Homo sapiens

<400>  9795
gaatgaatgg ctctggagca cctatgaatt tgaacaataa tctgaatcct atgtttcttg     60

gtccgttgaa tcctgttaac cctatccaga tgaactctca gagcagtgtg aagccactcc    120

ccatcaaccc tgatgatctg tatgtcagtg tgcatggaat gcccttttct gcaatggaaa    180

atgatgtcag agattttttt catgggctcc gtgttgatgc agtgcatttg ttgaaagatc    240

atgtaggtcg aaataatggg aatggattgg ttaagtttct ctcccctcaa gatacatttg    300

aagctttgaa acgaaacaga atgctgatga ttcaacgcta tgtggaagtt agccctgcca    360

cagaaagaca gtgggtagct gctggaggcc atatcacttt taagcaaaat atgggacctt    420

ctggacaaac tcatccccct cctcagacac ttcccaggtc aaaatcgccc agtgggcaga    480

aaagatcaag gtcaagatca ccacatgagg ctggtttttg tgtttacttg aaagggctac    540

catttgaagc agaaaacaaa catgtcattg atttttttaa aaagctggat attgtggaag    600

atagtattta tatagcttat ggacccaatg ggaaagcaac tggcgaaggc tttgtagagt    660

tcagaaatga ggctgactat aaggctgctc tgtgtcgtca taaacagtac atgggcaatc    720

gctttattca agttcatcca attactaaga aaggtatgct agaaaagata gatatgattc    780

gaaaaagact gcagaacttc agctatgacc agagggaaat gatactaaat ccagaggggg    840

atgtcaactc tgccaaatta ccctagaaga tatgagagag attgagaaaa atccccctgc    900

ccaaggaaaa aagggattaa agatgcctgt gccaggtaat cctgcagttc caggaatgcc    960

caatgcggga ctgcccggtg tgggactgcc cagtgcagga cttcccggtg caggcctgcc   1020

cagcacagga ctgcctggtt cagcaataac cagtgcagga ctgcctggtg cgggaatgcc   1080

cagtgcagga atacctagtg caggaggtga agagcatgcc ttcctgactg taggatcaaa   1140

ggaagccaat aatgggcctc catttaactt tcctggtaat tttggtggat caaatgcctt   1200

tgggccacca atccctcctc caggattagg aggcggggcc tttggtgatg ctaggcctgg   1260

tatgccttca gttggaaaca gtggtttgcc tggtctagga ctggatgttc cgggttttgg   1320

aggtggacca aacaatttaa gtgggccatc gggatttgga gggggccctc agaattttgg   1380

aaatggccct ggtagcttag gcggtccccc ggggtttgga agtggccctc ctggtcttgg   1440

aagtgcccct gggcatttgg gtgggccacc agcttttggg cctggccccg gccccggccc   1500

cggccctggc ccaatccata ttggtggtcc ccctggcttt gcatctagtt ctggaaaacc   1560

aggaccgaca gtaattaaag tgcaaaacat gccctttact gtgtctattg atgagatttt   1620

agatttcttt tatggctatc aagtaatccc aggctcagtg tgtttaaaat acaatgaaaa   1680

aggtatgccc acaggtgaag ccatggtggc ctttgagtct cgggatgaag ccacagctgc   1740

tgtcattgac ttaaatgaca ggcctatagg ttcaagaaaa gtaaaacttg tattagggta   1800

gccattcaca tcatttttta tagggtagat cttcatattg ctgtgattaa tgcatccaga   1860

ttgttttcct agtatttcca ggttagaacc tgtggattgt ttcaattgca tatagcttgg   1920

tttccataac atagagcatt ggttgactgt ttacagaaga ctcactcacc aggataaaca   1980

ttgctgtatg ttacagtaaa gctatctgga gagaacacat aaatgatttt ggcataccat   2040

tagagaaacc atttgtaaaa ctcaaatgac cacataaagc ttatcaagga gtctagattg   2100

gttttgtttt ataccatatg ggatgaagaa aatagaaatg tcagtagaac tcattgaggg   2160

tgctcttgcc agctgctgaa aatagaagtt ggctactctc agaatttggt ttaaagctgg   2220

acagatttgc tttgttatag ggtaaagctt tgtctaaagt cctcattttc ttttaaaatt   2280

gaataaaatt tctgtataca gattc                                         2305


<210>  9796
<211>  287
<212>  PRT
<213>  Homo sapiens

<400>  9796

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Leu Pro 
        275                 280                 285


<210>  9797
<211>  2476
<212>  DNA
<213>  Homo sapiens

<400>  9797
ttgcctcctg tgcctcctgt gcccccgatt cccccagttc cttctgtgcc acccatgacc     60

ccactgccac ccatgtcggg catgccgccc ttgaatccgc cacctgtggc acctctacct    120

gctggaatga atggctctgg agcacctatg aatttgaaca ataatctgaa tcctatgttt    180

cttggtccgt tgaatcctgt taaccctatc cagatgaact ctcagagcag tgtgaagcca    240

ctccccatca accctgatga tctgtatgtc agtgtgcatg gaatgccctt ttctgcaatg    300

gaaaatgatg tcagagattt ttttcatggg ctccgtgttg atgcagtgca tttgttgaaa    360

gatcatgtag gtcgaaataa tgggaatgga ttggttaagt ttctctcccc tcaagataca    420

tttgaagctt tgaaacgaaa cagaatgctg atgattcaac gctatgtgga agttagccct    480

gccacagaaa gacagtgggt agctgctgga ggccatatca cttttaagca aaatatggga    540

ccttctggac aaactcatcc ccctcctcag acacttccca ggtcaaaatc gcccagtggg    600

cagaaaagat caaggtcaag atcaccacat gaggctggtt tttgtgttta cttgaaaggg    660

ctaccatttg aagcagaaaa caaacatgtc attgattttt ttaaaaagct ggatattgtg    720

gaagatagta tttatatagc ttatggaccc aatgggaaag caactggcga aggctttgta    780

gagttcagaa atgaggctga ctataaggct gctctgtgtc gtcataaaca gtacatgggc    840

aatcgcttta ttcaagttca tccaattact aagaaaggta tgctagaaaa gatagatatg    900

attcgaaaaa gactgcagaa cttcagctat gaccagaggg aaatgatact aaatccagag    960

ggggatgtca actctgccaa agtctgtgcc cacataacaa atattccatt cagcattaca   1020

aagatggatg ttcttcagtt cctagaagga atcccagtgg atgaaaatgc tgtacatgtt   1080

cttgttgata acaatgggca aggtctagga caggcattgg ttcagaatgc ccaatgcggg   1140

actgcccggt gtgggactgc ccagtgcagg acttcccggt gcaggcctgc ccagcacagg   1200

actgcctggt tcagcaataa ccagtgcagg actgcctggt gcgggaatgc ccagtgcagg   1260

aatacctagt gcaggaggtg aagagcatgc cttcctgact gtaggatcaa aggaagccaa   1320

taatgggcct ccatttaact ttcctggtaa ttttggtgga tcaaatgcct ttgggccacc   1380

aatccctcct ccaggattag gaggcggggc ctttggtgat gctaggcctg gtatgccttc   1440

agttggaaac agtggtttgc ctggtctagg actggatgtt ccgggttttg gaggtggacc   1500

aaacaattta agtgggccat cgggatttgg agggggccct cagaattttg gaaatggccc   1560

tggtagctta ggcggtcccc cggggtttgg aagtggccct cctggtcttg gaagtgcccc   1620

tgggcatttg ggtgggccac cagcttttgg gcctggcccc ggccccggcc ccggccctgg   1680

cccaatccat attggtggtc cccctggctt tgcatctagt tctggaaaac caggaccgac   1740

agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt gatgagattt tagatttctt   1800

ttatggctat caagtaatcc caggctcagt gtgtttaaaa tacaatgaaa aaggtatgcc   1860

cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa gccacagctg ctgtcattga   1920

cttaaatgac aggcctatag gttcaagaaa agtaaaactt gtattagggt agccattcac   1980

atcatttttt atagggtaga tcttcatatt gctgtgatta atgcatccag attgttttcc   2040

tagtatttcc aggttagaac ctgtggattg tttcaattgc atatagcttg gtttccataa   2100

catagagcat tggttgactg tttacagaag actcactcac caggataaac attgctgtat   2160

gttacagtaa agctatctgg agagaacaca taaatgattt tggcatacca ttagagaaac   2220

catttgtaaa actcaaatga ccacataaag cttatcaagg agtctagatt ggttttgttt   2280

tataccatat gggatgaaga aaatagaaat gtcagtagaa ctcattgagg gtgctcttgc   2340

cagctgctga aaatagaagt tggctactct cagaatttgg tttaaagctg gacagatttg   2400

ctttgttata gggtaaagct ttgtctaaag tcctcatttt cttttaaaat tgaataaaat   2460

ttctgtatac agattc                                                   2476


<210>  9798
<211>  404
<212>  PRT
<213>  Homo sapiens

<400>  9798

Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro Pro 
1               5                   10                  15


Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro Met 
            20                  25                  30


Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn Pro 
        35                  40                  45


Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu Pro 
    50                  55                  60


Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe Ser 
65                  70                  75                  80


Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val Asp 
                85                  90                  95


Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn Gly 
            100                 105                 110


Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg 
        115                 120                 125


Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala Thr 
    130                 135                 140


Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln Asn 
145                 150                 155                 160


Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro Arg 
                165                 170                 175


Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro His 
            180                 185                 190


Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu 
        195                 200                 205


Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu Asp 
    210                 215                 220


Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly 
225                 230                 235                 240


Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg 
                245                 250                 255


His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile Thr 
            260                 265                 270


Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu Gln 
        275                 280                 285


Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly Asp 
    290                 295                 300


Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe Ser 
305                 310                 315                 320


Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val Asp 
                325                 330                 335


Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu Gly 
            340                 345                 350


Gln Ala Leu Val Gln Asn Ala Gln Cys Gly Thr Ala Arg Cys Gly Thr 
        355                 360                 365


Ala Gln Cys Arg Thr Ser Arg Cys Arg Pro Ala Gln His Arg Thr Ala 
    370                 375                 380


Trp Phe Ser Asn Asn Gln Cys Arg Thr Ala Trp Cys Gly Asn Ala Gln 
385                 390                 395                 400


Cys Arg Asn Thr 



<210>  9799
<211>  3232
<212>  DNA
<213>  Homo sapiens

<400>  9799
caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc cgtttgcaag gtctcccaat     60

tgtggcgggg accatggaca ttcgccactt cttctctgga ttgaccattc ctgatggggg    120

cgtgcatatt gtagggggtg aactgggtga ggctttcatc gtttttgcca ctgatgaaga    180

tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa gggtcaaaag taacactatt    240

gttgagtagt aagacggaaa tgcagaatat gattgaactg agtcgtaggc gttttgaaac    300

tgccaactta gatataccac cagcaaatgc cagtagatca ggaccaccac ctagctcagg    360

aatgagtagc agggtaaact tgcccacaac agtatccaac tttaataatc catcacccag    420

tgtagttact gccaccactt ctgttcatga aagcaacaaa aacatacaga cattttccac    480

agccagcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc caacgtttag    540

ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac caattcctcc    600

aattccagcg atgccatctt ctgtgccacc catgacccca ctgccaccca tgtcgggcat    660

gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg gctctggagc    720

acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga atcctgttaa    780

ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc ctgatgatct    840

gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca gagatttttt    900

tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc gaaataatgg    960

gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga aacgaaacag   1020

aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac agtgggtagc   1080

tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa ctcatccccc   1140

tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc   1200

accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag cagaaaacaa   1260

acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt atatagctta   1320

tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg aggctgacta   1380

taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc aagttcatcc   1440

aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac tgcagaactt   1500

cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact ctgccaaagt   1560

ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc ttcagttcct   1620

agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca atgggcaagg   1680

tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt   1740

acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc tagaagatat   1800

gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc   1860

aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg gactgcccag   1920

tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag caataaccag   1980

tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag gaggtgaaga   2040

gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat ttaactttcc   2100

tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag gattaggagg   2160

cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg   2220

tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg ggccatcggg   2280

atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg gtcccccggg   2340

gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg ggccaccagc   2400

ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg gtggtccccc   2460

tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc aaaacatgcc   2520

ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag taatcccagg   2580

ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt   2640

tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc ctataggttc   2700

aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag ggtagatctt   2760

catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt tagaacctgt   2820

ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt tgactgttta   2880

cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct atctggagag   2940

aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc aaatgaccac   3000

ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga tgaagaaaat   3060

agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat agaagttggc   3120

tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt aaagctttgt   3180

ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat tc           3232


<210>  9800
<211>  900
<212>  PRT
<213>  Homo sapiens

<400>  9800

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
        195                 200                 205


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
    210                 215                 220


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
225                 230                 235                 240


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
                245                 250                 255


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
            260                 265                 270


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
        275                 280                 285


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
    290                 295                 300


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
305                 310                 315                 320


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
                325                 330                 335


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
            340                 345                 350


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
        355                 360                 365


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
    370                 375                 380


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
385                 390                 395                 400


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
                405                 410                 415


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
            420                 425                 430


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
        435                 440                 445


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
    450                 455                 460


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
465                 470                 475                 480


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
                485                 490                 495


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
            500                 505                 510


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
        515                 520                 525


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
    530                 535                 540


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
545                 550                 555                 560


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
                565                 570                 575


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
            580                 585                 590


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
        595                 600                 605


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
    610                 615                 620


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
625                 630                 635                 640


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
                645                 650                 655


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
            660                 665                 670


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
        675                 680                 685


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
    690                 695                 700


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
705                 710                 715                 720


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
                725                 730                 735


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
            740                 745                 750


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
        755                 760                 765


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
    770                 775                 780


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
785                 790                 795                 800


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
                805                 810                 815


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
            820                 825                 830


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
        835                 840                 845


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
    850                 855                 860


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
865                 870                 875                 880


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
                885                 890                 895


Leu Val Leu Gly 
            900


<210>  9801
<211>  3494
<212>  DNA
<213>  Homo sapiens

<400>  9801
gaaatgcctc cgaggtccat tgctggggag gggctttact cgagggtgta gcagttttga     60

gaagccggcg tctgaagcta ggagtctaaa agttggtttt aattggttgc ccacaggatt    120

gacttggcct ctacttcttg ttaaggaaat tcatctcttg ttttatcagg tgtgtgtggt    180

ttcagcgcag catggctgtg gtcatccgtt tgcaaggtct cccaattgtg gcggggacca    240

tggacattcg ccacttcttc tctggattga ccattcctga tgggggcgtg catattgtag    300

ggggtgaact gggtgaggct ttcatcgttt ttgccactga tgaagatgca aggcttggta    360

tgatgcgcac aggtggtaca attaaagggt caaaagtaac actattgttg agtagtaaga    420

cggaaatgca gaatatgatt gaactgagtc gtaggcgttt tgaaactgcc aacttagata    480

taccaccagc aaatgccagt agatcaggac caccacctag ctcaggaatg agtagcaggg    540

taaacttgcc cacaacagta tccaacttta ataatccatc acccagtgta gttactgcca    600

ccacttctgt tcatgaaagc aacaaaaaca tacagacatt ttccacagcc agcgtaggaa    660

cagctcctcc aaatatgggg gcttcctttg ggagcccaac gtttagctca actgttccaa    720

gcacagcctc tccaatgaac acagtcccgc cgccaccaat tcctccaatt ccagcgatgc    780

catctctgcc accaatgcca tccattcccc caattccagt tcctcctcca gtacctacat    840

tgcctcctgt gcctcctgtg cccccgattc ccccagttcc ttctgtgcca cccatgaccc    900

cactgccacc catgtcgggc atgccgccct tgaatccgcc acctgtggca cctctacctg    960

ctggaatgaa tggctctgga gcacctatga atttgaacaa taatctgaat cctatgtttc   1020

ttggtccgtt gaatcctgtt aaccctatcc agatgaactc tcagagcagt gtgaagccac   1080

tccccatcaa ccctgatgat ctgtatgtca gtgtgcatgg aatgcccttt tctgcaatgg   1140

aaaatgatgt cagagatttt tttcatgggc tccgtgttga tgcagtgcat ttgttgaaag   1200

atcatgtagg tcgaaataat gggaatggat tggttaagtt tctctcccct caagatacat   1260

ttgaagcttt gaaacgaaac agaatgctga tgattcaacg ctatgtggaa gttagccctg   1320

ccacagaaag acagtgggta gctgctggag gccatatcac ttttaagcaa aatatgggac   1380

cttctggaca aactcatccc cctcctcaga cacttcccag gtcaaaatcg cccagtgggc   1440

agaaaagatc aaggtcaaga tcaccacatg aggctggttt ttgtgtttac ttgaaagggc   1500

taccatttga agcagaaaac aaacatgtca ttgatttttt taaaaagctg gatattgtgg   1560

aagatagtat ttatatagct tatggaccca atgggaaagc aactggcgaa ggctttgtag   1620

agttcagaaa tgaggctgac tataaggctg ctctgtgtcg tcataaacag tacatgggca   1680

atcgctttat tcaagttcat ccaattacta agaaaggtat gctagaaaag atagatatga   1740

ttcgaaaaag actgcagaac ttcagctatg accagaggga aatgatacta aatccagagg   1800

gggatgtcaa ctctgccaaa gtctgtgccc acataacaaa tattccattc agcattacaa   1860

agatggatgt tcttcagttc ctagaaggaa tcccagtgga tgaaaatgct gtacatgttc   1920

ttgttgataa caatgggcaa ggtctaggac aggcattggt tcagtttaaa aatgaagatg   1980

atgcacgtaa gtctgaacgc ttacaccgta aaaaacttaa tgggagagaa gcttttgttc   2040

atgtagttac cctagaagat atgagagaga ttgagaaaaa tccccctgcc caaggaaaaa   2100

agggattaaa gatgcctgtg ccaggtaatc ctgcagttcc aggaatgccc aatgcgggac   2160

tgcccggtgt gggactgccc agtgcaggac ttcccggtgc aggcctgccc agcacaggac   2220

tgcctggttc agcaataacc agtgcaggac tgcctggtgc gggaatgccc agtgcaggaa   2280

tacctagtgc aggaggtgaa gagcatgcct tcctgactgt aggatcaaag gaagccaata   2340

atgggcctcc atttaacttt cctggtaatt ttggtggatc aaatgccttt gggccaccaa   2400

tccctcctcc aggattagga ggcggggcct ttggtgatgc taggcctggt atgccttcag   2460

ttggaaacag tggtttgcct ggtctaggac tggatgttcc gggttttgga ggtggaccaa   2520

acaatttaag tgggccatcg ggatttggag ggggccctca gaattttgga aatggccctg   2580

gtagcttagg cggtcccccg gggtttggaa gtggccctcc tggtcttgga agtgcccctg   2640

ggcatttggg tgggccacca gcttttgggc ctggccccgg ccccggcccc ggccctggcc   2700

caatccatat tggtggtccc cctggctttg catctagttc tggaaaacca ggaccgacag   2760

taattaaagt gcaaaacatg ccctttactg tgtctattga tgagatttta gatttctttt   2820

atggctatca agtaatccca ggctcagtgt gtttaaaata caatgaaaaa ggtatgccca   2880

caggtgaagc catggtggcc tttgagtctc gggatgaagc cacagctgct gtcattgact   2940

taaatgacag gcctataggt tcaagaaaag taaaacttgt attagggtag ccattcacat   3000

cattttttat agggtagatc ttcatattgc tgtgattaat gcatccagat tgttttccta   3060

gtatttccag gttagaacct gtggattgtt tcaattgcat atagcttggt ttccataaca   3120

tagagcattg gttgactgtt tacagaagac tcactcacca ggataaacat tgctgtatgt   3180

tacagtaaag ctatctggag agaacacata aatgattttg gcataccatt agagaaacca   3240

tttgtaaaac tcaaatgacc acataaagct tatcaaggag tctagattgg ttttgtttta   3300

taccatatgg gatgaagaaa atagaaatgt cagtagaact cattgagggt gctcttgcca   3360

gctgctgaaa atagaagttg gctactctca gaatttggtt taaagctgga cagatttgct   3420

ttgttatagg gtaaagcttt gtctaaagtc ctcattttct tttaaaattg aataaaattt   3480

ctgtatacag attc                                                     3494


<210>  9802
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9802

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9803
<211>  3403
<212>  DNA
<213>  Homo sapiens

<400>  9803
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

cattcctgat gggggcgtgc atattgtagg gggtgaactg ggtgaggctt tcatcgtttt    240

tgccactgat gaagatgcaa ggcttggtat gatgcgcaca ggtggtacaa ttaaagggtc    300

aaaagtaaca ctattgttga gtagtaagac ggaaatgcag aatatgattg aactgagtcg    360

taggcgtttt gaaactgcca acttagatat accaccagca aatgccagta gatcaggacc    420

accacctagc tcaggaatga gtagcagggt aaacttgccc acaacagtat ccaactttaa    480

taatccatca cccagtgtag ttactgccac cacttctgtt catgaaagca acaaaaacat    540

acagacattt tccacagcca gcgtaggaac agctcctcca aatatggggg cttcctttgg    600

gagcccaacg tttagctcaa ctgttccaag cacagcctct ccaatgaaca cagtcccgcc    660

gccaccaatt cctccaattc cagcgatgcc atctctgcca ccaatgccat ccattccccc    720

aattccagtt cctcctccag tacctacatt gcctcctgtg cctcctgtgc ccccgattcc    780

cccagttcct tctgtgccac ccatgacccc actgccaccc atgtcgggca tgccgccctt    840

gaatccgcca cctgtggcac ctctacctgc tggaatgaat ggctctggag cacctatgaa    900

tttgaacaat aatctgaatc ctatgtttct tggtccgttg aatcctgtta accctatcca    960

gatgaactct cagagcagtg tgaagccact ccccatcaac cctgatgatc tgtatgtcag   1020

tgtgcatgga atgccctttt ctgcaatgga aaatgatgtc agagattttt ttcatgggct   1080

ccgtgttgat gcagtgcatt tgttgaaaga tcatgtaggt cgaaataatg ggaatggatt   1140

ggttaagttt ctctcccctc aagatacatt tgaagctttg aaacgaaaca gaatgctgat   1200

gattcaacgc tatgtggaag ttagccctgc cacagaaaga cagtgggtag ctgctggagg   1260

ccatatcact tttaagcaaa atatgggacc ttctggacaa actcatcccc ctcctcagac   1320

acttcccagg tcaaaatcgc ccagtgggca gaaaagatca aggtcaagat caccacatga   1380

ggctggtttt tgtgtttact tgaaagggct accatttgaa gcagaaaaca aacatgtcat   1440

tgattttttt aaaaagctgg atattgtgga agatagtatt tatatagctt atggacccaa   1500

tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact ataaggctgc   1560

tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc caattactaa   1620

gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact tcagctatga   1680

ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag tctgtgccca   1740

cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc tagaaggaat   1800

cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag gtctaggaca   1860

ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct tacaccgtaa   1920

aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata tgagagagat   1980

tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc caggtaatcc   2040

tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca gtgcaggact   2100

tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca gtgcaggact   2160

gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag agcatgcctt   2220

cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc ctggtaattt   2280

tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag gcggggcctt   2340

tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg gtctaggact   2400

ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg gatttggagg   2460

gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg ggtttggaag   2520

tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag cttttgggcc   2580

tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc ctggctttgc   2640

atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc cctttactgt   2700

gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag gctcagtgtg   2760

tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct ttgagtctcg   2820

ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt caagaaaagt   2880

aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct tcatattgct   2940

gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg tggattgttt   3000

caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt acagaagact   3060

cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga gaacacataa   3120

atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca cataaagctt   3180

atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa tagaaatgtc   3240

agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg ctactctcag   3300

aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg tctaaagtcc   3360

tcattttctt ttaaaattga ataaaatttc tgtatacaga ttc                     3403


<210>  9804
<211>  876
<212>  PRT
<213>  Homo sapiens

<400>  9804

Met Met Arg Thr Gly Gly Thr Ile Lys Gly Ser Lys Val Thr Leu Leu 
1               5                   10                  15


Leu Ser Ser Lys Thr Glu Met Gln Asn Met Ile Glu Leu Ser Arg Arg 
            20                  25                  30


Arg Phe Glu Thr Ala Asn Leu Asp Ile Pro Pro Ala Asn Ala Ser Arg 
        35                  40                  45


Ser Gly Pro Pro Pro Ser Ser Gly Met Ser Ser Arg Val Asn Leu Pro 
    50                  55                  60


Thr Thr Val Ser Asn Phe Asn Asn Pro Ser Pro Ser Val Val Thr Ala 
65                  70                  75                  80


Thr Thr Ser Val His Glu Ser Asn Lys Asn Ile Gln Thr Phe Ser Thr 
                85                  90                  95


Ala Ser Val Gly Thr Ala Pro Pro Asn Met Gly Ala Ser Phe Gly Ser 
            100                 105                 110


Pro Thr Phe Ser Ser Thr Val Pro Ser Thr Ala Ser Pro Met Asn Thr 
        115                 120                 125


Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro Ser Leu Pro 
    130                 135                 140


Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr 
145                 150                 155                 160


Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val 
                165                 170                 175


Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn 
            180                 185                 190


Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala 
        195                 200                 205


Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu 
    210                 215                 220


Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro 
225                 230                 235                 240


Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro 
                245                 250                 255


Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg 
            260                 265                 270


Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly 
        275                 280                 285


Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu 
    290                 295                 300


Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro 
305                 310                 315                 320


Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys 
                325                 330                 335


Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu 
            340                 345                 350


Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser 
        355                 360                 365


Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu 
    370                 375                 380


Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val 
385                 390                 395                 400


Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly 
                405                 410                 415


Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu 
            420                 425                 430


Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro 
        435                 440                 445


Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg 
    450                 455                 460


Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu 
465                 470                 475                 480


Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro 
                485                 490                 495


Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro 
            500                 505                 510


Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly 
        515                 520                 525


Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys 
    530                 535                 540


Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val 
545                 550                 555                 560


His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro 
                565                 570                 575


Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala 
            580                 585                 590


Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser 
        595                 600                 605


Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser 
    610                 615                 620


Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly 
625                 630                 635                 640


Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser 
                645                 650                 655


Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly 
            660                 665                 670


Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly 
        675                 680                 685


Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser 
    690                 695                 700


Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro 
705                 710                 715                 720


Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe 
                725                 730                 735


Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly 
            740                 745                 750


Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala 
        755                 760                 765


Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile 
    770                 775                 780


Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr 
785                 790                 795                 800


Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile 
                805                 810                 815


Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu 
            820                 825                 830


Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe 
        835                 840                 845


Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg 
    850                 855                 860


Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
865                 870                 875


<210>  9805
<211>  2918
<212>  DNA
<213>  Homo sapiens

<400>  9805
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatcttc tgccaccaat gccatccatt cccccaattc    240

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    300

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    360

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    420

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    480

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    540

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    600

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    660

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    720

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    780

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    840

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    900

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt    960

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1020

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1080

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1140

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1200

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1260

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1320

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1380

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1440

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1500

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1560

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1620

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1680

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1740

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1800

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1860

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1920

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   1980

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2040

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2100

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2160

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2220

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2280

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2340

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2400

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2460

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2520

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2580

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2640

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2700

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2760

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2820

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2880

ttcttttaaa attgaataaa atttctgtat acagattc                           2918


<210>  9806
<211>  731
<212>  PRT
<213>  Homo sapiens

<400>  9806

Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro Val Pro Thr Leu 
1               5                   10                  15


Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val Pro Ser Val Pro 
            20                  25                  30


Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro Pro Leu Asn Pro 
        35                  40                  45


Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly Ser Gly Ala Pro 
    50                  55                  60


Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu Gly Pro Leu Asn 
65                  70                  75                  80


Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser Val Lys Pro Leu 
                85                  90                  95


Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His Gly Met Pro Phe 
            100                 105                 110


Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His Gly Leu Arg Val 
        115                 120                 125


Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg Asn Asn Gly Asn 
    130                 135                 140


Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe Glu Ala Leu Lys 
145                 150                 155                 160


Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu Val Ser Pro Ala 
                165                 170                 175


Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile Thr Phe Lys Gln 
            180                 185                 190


Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro Gln Thr Leu Pro 
        195                 200                 205


Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg Ser Arg Ser Pro 
    210                 215                 220


His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu Pro Phe Glu Ala 
225                 230                 235                 240


Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu Asp Ile Val Glu 
                245                 250                 255


Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys Ala Thr Gly Glu 
            260                 265                 270


Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys Ala Ala Leu Cys 
        275                 280                 285


Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln Val His Pro Ile 
    290                 295                 300


Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile Arg Lys Arg Leu 
305                 310                 315                 320


Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu Asn Pro Glu Gly 
                325                 330                 335


Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr Asn Ile Pro Phe 
            340                 345                 350


Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu Gly Ile Pro Val 
        355                 360                 365


Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn Gly Gln Gly Leu 
    370                 375                 380


Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp Ala Arg Lys Ser 
385                 390                 395                 400


Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu Ala Phe Val His 
                405                 410                 415


Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys Asn Pro Pro Ala 
            420                 425                 430


Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly Asn Pro Ala Val 
        435                 440                 445


Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly Leu Pro Ser Ala 
    450                 455                 460


Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu Pro Gly Ser Ala 
465                 470                 475                 480


Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro Ser Ala Gly Ile 
                485                 490                 495


Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr Val Gly Ser Lys 
            500                 505                 510


Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly Asn Phe Gly Gly 
        515                 520                 525


Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly Leu Gly Gly Gly 
    530                 535                 540


Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val Gly Asn Ser Gly 
545                 550                 555                 560


Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly Gly Gly Pro Asn 
                565                 570                 575


Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro Gln Asn Phe Gly 
            580                 585                 590


Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe Gly Ser Gly Pro 
        595                 600                 605


Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly Pro Pro Ala Phe 
    610                 615                 620


Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Ile His Ile Gly 
625                 630                 635                 640


Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro Gly Pro Thr Val 
                645                 650                 655


Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile Asp Glu Ile Leu 
            660                 665                 670


Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser Val Cys Leu Lys 
        675                 680                 685


Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met Val Ala Phe Glu 
    690                 695                 700


Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu Asn Asp Arg Pro 
705                 710                 715                 720


Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
                725                 730


<210>  9807
<211>  3012
<212>  DNA
<213>  Homo sapiens

<400>  9807
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg tgttccaagc    240

acagcctctc caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca    300

tctctgccac caatgccatc cattccccca attccagttc ctcctccagt acctacattg    360

cctcctgtgc ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca    420

ctgccaccca tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct    480

ggaatgaatg gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt    540

ggtccgttga atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc    600

cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa    660

aatgatgtca gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat    720

catgtaggtc gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt    780

gaagctttga aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc    840

acagaaagac agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct    900

tctggacaaa ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag    960

aaaagatcaa ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta   1020

ccatttgaag cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa   1080

gatagtattt atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag   1140

ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat   1200

cgctttattc aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt   1260

cgaaaaagac tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg   1320

gatgtcaact ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag   1380

atggatgttc ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt   1440

gttgataaca atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat   1500

gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat   1560

gtagttaccc tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag   1620

ggattaaaga tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg   1680

cccggtgtgg gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg   1740

cctggttcag caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata   1800

cctagtgcag gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat   1860

gggcctccat ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc   1920

cctcctccag gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt   1980

ggaaacagtg gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac   2040

aatttaagtg ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt   2100

agcttaggcg gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg   2160

catttgggtg ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca   2220

atccatattg gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta   2280

attaaagtgc aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat   2340

ggctatcaag taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca   2400

ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta   2460

aatgacaggc ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca   2520

ttttttatag ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt   2580

atttccaggt tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata   2640

gagcattggt tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta   2700

cagtaaagct atctggagag aacacataaa tgattttggc ataccattag agaaaccatt   2760

tgtaaaactc aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata   2820

ccatatggga tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc   2880

tgctgaaaat agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt   2940

gttatagggt aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct   3000

gtatacagat tc                                                       3012


<210>  9808
<211>  751
<212>  PRT
<213>  Homo sapiens

<400>  9808

Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile Pro Ala Met Pro 
1               5                   10                  15


Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro Val Pro Pro Pro 
            20                  25                  30


Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro Ile Pro Pro Val 
        35                  40                  45


Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met Ser Gly Met Pro 
    50                  55                  60


Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala Gly Met Asn Gly 
65                  70                  75                  80


Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro Met Phe Leu 
                85                  90                  95


Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser Gln Ser Ser 
            100                 105                 110


Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val Ser Val His 
        115                 120                 125


Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp Phe Phe His 
    130                 135                 140


Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His Val Gly Arg 
145                 150                 155                 160


Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln Asp Thr Phe 
                165                 170                 175


Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg Tyr Val Glu 
            180                 185                 190


Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly Gly His Ile 
        195                 200                 205


Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His Pro Pro Pro 
    210                 215                 220


Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys Arg Ser Arg 
225                 230                 235                 240


Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu Lys Gly Leu 
                245                 250                 255


Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe Lys Lys Leu 
            260                 265                 270


Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro Asn Gly Lys 
        275                 280                 285


Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala Asp Tyr Lys 
    290                 295                 300


Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg Phe Ile Gln 
305                 310                 315                 320


Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile Asp Met Ile 
                325                 330                 335


Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu Met Ile Leu 
            340                 345                 350


Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala His Ile Thr 
        355                 360                 365


Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln Phe Leu Glu 
    370                 375                 380


Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val Asp Asn Asn 
385                 390                 395                 400


Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn Glu Asp Asp 
                405                 410                 415


Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn Gly Arg Glu 
            420                 425                 430


Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu Ile Glu Lys 
        435                 440                 445


Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro Val Pro Gly 
    450                 455                 460


Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro Gly Val Gly 
465                 470                 475                 480


Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser Thr Gly Leu 
                485                 490                 495


Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala Gly Met Pro 
            500                 505                 510


Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala Phe Leu Thr 
        515                 520                 525


Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn Phe Pro Gly 
    530                 535                 540


Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro Pro Pro Gly 
545                 550                 555                 560


Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met Pro Ser Val 
                565                 570                 575


Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro Gly Phe Gly 
            580                 585                 590


Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly Gly Gly Pro 
        595                 600                 605


Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro Pro Gly Phe 
    610                 615                 620


Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His Leu Gly Gly 
625                 630                 635                 640


Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro Gly Pro 
                645                 650                 655


Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser Gly Lys Pro 
            660                 665                 670


Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr Val Ser Ile 
        675                 680                 685


Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile Pro Gly Ser 
    690                 695                 700


Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly Glu Ala Met 
705                 710                 715                 720


Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val Ile Asp Leu 
                725                 730                 735


Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val Leu Gly 
            740                 745                 750


<210>  9809
<211>  2978
<212>  DNA
<213>  Homo sapiens

<400>  9809
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgcgta ggaacagctc ctccaaatat gggggcttcc tttgggagcc    180

caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc ccgccgccac    240

caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt cccccaattc    300

cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg attcccccag    360

ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg cccttgaatc    420

cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct atgaatttga    480

acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct atccagatga    540

actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat gtcagtgtgc    600

atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat gggctccgtg    660

ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat ggattggtta    720

agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg ctgatgattc    780

aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct ggaggccata    840

tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct cagacacttc    900

ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca catgaggctg    960

gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat gtcattgatt   1020

tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga cccaatggga   1080

aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag gctgctctgt   1140

gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt actaagaaag   1200

gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc tatgaccaga   1260

gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt gcccacataa   1320

caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa ggaatcccag   1380

tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta ggacaggcat   1440

tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac cgtaaaaaac   1500

ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga gagattgaga   1560

aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt aatcctgcag   1620

ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca ggacttcccg   1680

gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca ggactgcctg   1740

gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat gccttcctga   1800

ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt aattttggtg   1860

gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg gcctttggtg   1920

atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta ggactggatg   1980

ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt ggagggggcc   2040

ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt ggaagtggcc   2100

ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt gggcctggcc   2160

ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc tttgcatcta   2220

gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt actgtgtcta   2280

ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca gtgtgtttaa   2340

aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag tctcgggatg   2400

aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga aaagtaaaac   2460

ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata ttgctgtgat   2520

taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat tgtttcaatt   2580

gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga agactcactc   2640

accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca cataaatgat   2700

tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa agcttatcaa   2760

ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa atgtcagtag   2820

aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact ctcagaattt   2880

ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa agtcctcatt   2940

ttcttttaaa attgaataaa atttctgtat acagattc                           2978


<210>  9810
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9810

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9811
<211>  3087
<212>  DNA
<213>  Homo sapiens

<400>  9811
gtgaagcggc gaaggaggtg gtggctgcgt tgggctccgg gaagccgttc gggctggggc     60

tgtcggccgc ggggcggagg cactcgcgcg gggggtaatt cggggtctgg gttctggtgc    120

cgcgcagctt tccccgtcta aaagttggtt ttaattggtt gcccacagga ttgacttggc    180

ctctacttct tgttaaggaa attcatctct tgttttatca ggtgtgtgtg gtttcagcgc    240

accagcgtag gaacagctcc tccaaatatg ggggcttcct ttgggagccc aacgtttagc    300

tcaactgttc caagcacagc ctctccaatg aacacagtcc cgccgccacc aattcctcca    360

attccagcga tgccatctct gccaccaatg ccatccattc ccccaattcc agttcctcct    420

ccagtaccta cattgcctcc tgtgcctcct gtgcccccga ttcccccagt tccttctgtg    480

ccacccatga ccccactgcc acccatgtcg ggcatgccgc ccttgaatcc gccacctgtg    540

gcacctctac ctgctggaat gaatggctct ggagcaccta tgaatttgaa caataatctg    600

aatcctatgt ttcttggtcc gttgaatcct gttaacccta tccagatgaa ctctcagagc    660

agtgtgaagc cactccccat caaccctgat gatctgtatg tcagtgtgca tggaatgccc    720

ttttctgcaa tggaaaatga tgtcagagat ttttttcatg ggctccgtgt tgatgcagtg    780

catttgttga aagatcatgt aggtcgaaat aatgggaatg gattggttaa gtttctctcc    840

cctcaagata catttgaagc tttgaaacga aacagaatgc tgatgattca acgctatgtg    900

gaagttagcc ctgccacaga aagacagtgg gtagctgctg gaggccatat cacttttaag    960

caaaatatgg gaccttctgg acaaactcat ccccctcctc agacacttcc caggtcaaaa   1020

tcgcccagtg ggcagaaaag atcaaggtca agatcaccac atgaggctgg tttttgtgtt   1080

tacttgaaag ggctaccatt tgaagcagaa aacaaacatg tcattgattt ttttaaaaag   1140

ctggatattg tggaagatag tatttatata gcttatggac ccaatgggaa agcaactggc   1200

gaaggctttg tagagttcag aaatgaggct gactataagg ctgctctgtg tcgtcataaa   1260

cagtacatgg gcaatcgctt tattcaagtt catccaatta ctaagaaagg tatgctagaa   1320

aagatagata tgattcgaaa aagactgcag aacttcagct atgaccagag ggaaatgata   1380

ctaaatccag agggggatgt caactctgcc aaagtctgtg cccacataac aaatattcca   1440

ttcagcatta caaagatgga tgttcttcag ttcctagaag gaatcccagt ggatgaaaat   1500

gctgtacatg ttcttgttga taacaatggg caaggtctag gacaggcatt ggttcagttt   1560

aaaaatgaag atgatgcacg taagtctgaa cgcttacacc gtaaaaaact taatgggaga   1620

gaagcttttg ttcatgtagt taccctagaa gatatgagag agattgagaa aaatccccct   1680

gcccaaggaa aaaagggatt aaagatgcct gtgccaggta atcctgcagt tccaggaatg   1740

cccaatgcgg gactgcccgg tgtgggactg cccagtgcag gacttcccgg tgcaggcctg   1800

cccagcacag gactgcctgg ttcagcaata accagtgcag gactgcctgg tgcgggaatg   1860

cccagtgcag gaatacctag tgcaggaggt gaagagcatg ccttcctgac tgtaggatca   1920

aaggaagcca ataatgggcc tccatttaac tttcctggta attttggtgg atcaaatgcc   1980

tttgggccac caatccctcc tccaggatta ggaggcgggg cctttggtga tgctaggcct   2040

ggtatgcctt cagttggaaa cagtggtttg cctggtctag gactggatgt tccgggtttt   2100

ggaggtggac caaacaattt aagtgggcca tcgggatttg gagggggccc tcagaatttt   2160

ggaaatggcc ctggtagctt aggcggtccc ccggggtttg gaagtggccc tcctggtctt   2220

ggaagtgccc ctgggcattt gggtgggcca ccagcttttg ggcctggccc cggccccggc   2280

cccggccctg gcccaatcca tattggtggt ccccctggct ttgcatctag ttctggaaaa   2340

ccaggaccga cagtaattaa agtgcaaaac atgcccttta ctgtgtctat tgatgagatt   2400

ttagatttct tttatggcta tcaagtaatc ccaggctcag tgtgtttaaa atacaatgaa   2460

aaaggtatgc ccacaggtga agccatggtg gcctttgagt ctcgggatga agccacagct   2520

gctgtcattg acttaaatga caggcctata ggttcaagaa aagtaaaact tgtattaggg   2580

tagccattca catcattttt tatagggtag atcttcatat tgctgtgatt aatgcatcca   2640

gattgttttc ctagtatttc caggttagaa cctgtggatt gtttcaattg catatagctt   2700

ggtttccata acatagagca ttggttgact gtttacagaa gactcactca ccaggataaa   2760

cattgctgta tgttacagta aagctatctg gagagaacac ataaatgatt ttggcatacc   2820

attagagaaa ccatttgtaa aactcaaatg accacataaa gcttatcaag gagtctagat   2880

tggttttgtt ttataccata tgggatgaag aaaatagaaa tgtcagtaga actcattgag   2940

ggtgctcttg ccagctgctg aaaatagaag ttggctactc tcagaatttg gtttaaagct   3000

ggacagattt gctttgttat agggtaaagc tttgtctaaa gtcctcattt tcttttaaaa   3060

ttgaataaaa tttctgtata cagattc                                       3087


<210>  9812
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  9812

Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro Ser 
1               5                   10                  15


Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro Ile 
            20                  25                  30


Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile Pro 
        35                  40                  45


Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro Pro 
    50                  55                  60


Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro Met 
65                  70                  75                  80


Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro Ala 
                85                  90                  95


Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn 
            100                 105                 110


Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn 
        115                 120                 125


Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr 
    130                 135                 140


Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg 
145                 150                 155                 160


Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp 
                165                 170                 175


His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro 
            180                 185                 190


Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln 
        195                 200                 205


Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala 
    210                 215                 220


Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr 
225                 230                 235                 240


His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln 
                245                 250                 255


Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr 
            260                 265                 270


Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe 
        275                 280                 285


Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly 
    290                 295                 300


Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu 
305                 310                 315                 320


Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn 
                325                 330                 335


Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys 
            340                 345                 350


Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg 
        355                 360                 365


Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys 
    370                 375                 380


Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu 
385                 390                 395                 400


Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu 
                405                 410                 415


Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys 
            420                 425                 430


Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu 
        435                 440                 445


Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg 
    450                 455                 460


Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met 
465                 470                 475                 480


Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu 
                485                 490                 495


Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro 
            500                 505                 510


Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly 
        515                 520                 525


Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His 
    530                 535                 540


Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe 
545                 550                 555                 560


Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile 
                565                 570                 575


Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly 
            580                 585                 590


Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val 
        595                 600                 605


Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe 
    610                 615                 620


Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly 
625                 630                 635                 640


Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly 
                645                 650                 655


His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro 
            660                 665                 670


Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser 
        675                 680                 685


Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe 
    690                 695                 700


Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val 
705                 710                 715                 720


Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr 
                725                 730                 735


Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala 
            740                 745                 750


Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu 
        755                 760                 765


Val Leu Gly 
    770


<210>  9813
<211>  2732
<212>  DNA
<213>  Homo sapiens

<400>  9813
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccgtctaa aagttggttt taattggttg cccacaggat    180

tgacttggcc tctacctgct ggaatgaatg gctctggagc acctatgaat ttgaacaata    240

atctgaatcc tatgtttctt ggtccgttga atcctgttaa ccctatccag atgaactctc    300

agagcagtgt gaagccactc cccatcaacc ctgatgatct gtatgtcagt gtgcatggaa    360

tgcccttttc tgcaatggaa aatgatgtca gagatttttt tcatgggctc cgtgttgatg    420

cagtgcattt gttgaaagat catgtaggtc gaaataatgg gaatggattg gttaagtttc    480

tctcccctca agatacattt gaagctttga aacgaaacag aatgctgatg attcaacgct    540

atgtggaagt tagccctgcc acagaaagac agtgggtagc tgctggaggc catatcactt    600

ttaagcaaaa tatgggacct tctggacaaa ctcatccccc tcctcagaca cttcccaggt    660

caaaatcgcc cagtgggcag aaaagatcaa ggtcaagatc accacatgag gctggttttt    720

gtgtttactt gaaagggcta ccatttgaag cagaaaacaa acatgtcatt gattttttta    780

aaaagctgga tattgtggaa gatagtattt atatagctta tggacccaat gggaaagcaa    840

ctggcgaagg ctttgtagag ttcagaaatg aggctgacta taaggctgct ctgtgtcgtc    900

ataaacagta catgggcaat cgctttattc aagttcatcc aattactaag aaaggtatgc    960

tagaaaagat agatatgatt cgaaaaagac tgcagaactt cagctatgac cagagggaaa   1020

tgatactaaa tccagagggg gatgtcaact ctgccaaagt ctgtgcccac ataacaaata   1080

ttccattcag cattacaaag atggatgttc ttcagttcct agaaggaatc ccagtggatg   1140

aaaatgctgt acatgttctt gttgataaca atgggcaagg tctaggacag gcattggttc   1200

agtttaaaaa tgaagatgat gcacgtaagt ctgaacgctt acaccgtaaa aaacttaatg   1260

ggagagaagc ttttgttcat gtagttaccc tagaagatat gagagagatt gagaaaaatc   1320

cccctgccca aggaaaaaag ggattaaaga tgcctgtgcc aggtaatcct gcagttccag   1380

gaatgcccaa tgcgggactg cccggtgtgg gactgcccag tgcaggactt cccggtgcag   1440

gcctgcccag cacaggactg cctggttcag caataaccag tgcaggactg cctggtgcgg   1500

gaatgcccag tgcaggaata cctagtgcag gaggtgaaga gcatgccttc ctgactgtag   1560

gatcaaagga agccaataat gggcctccat ttaactttcc tggtaatttt ggtggatcaa   1620

atgcctttgg gccaccaatc cctcctccag gattaggagg cggggccttt ggtgatgcta   1680

ggcctggtat gccttcagtt ggaaacagtg gtttgcctgg tctaggactg gatgttccgg   1740

gttttggagg tggaccaaac aatttaagtg ggccatcggg atttggaggg ggccctcaga   1800

attttggaaa tggccctggt agcttaggcg gtcccccggg gtttggaagt ggccctcctg   1860

gtcttggaag tgcccctggg catttgggtg ggccaccagc ttttgggcct ggccccggcc   1920

ccggccccgg ccctggccca atccatattg gtggtccccc tggctttgca tctagttctg   1980

gaaaaccagg accgacagta attaaagtgc aaaacatgcc ctttactgtg tctattgatg   2040

agattttaga tttcttttat ggctatcaag taatcccagg ctcagtgtgt ttaaaataca   2100

atgaaaaagg tatgcccaca ggtgaagcca tggtggcctt tgagtctcgg gatgaagcca   2160

cagctgctgt cattgactta aatgacaggc ctataggttc aagaaaagta aaacttgtat   2220

tagggtagcc attcacatca ttttttatag ggtagatctt catattgctg tgattaatgc   2280

atccagattg ttttcctagt atttccaggt tagaacctgt ggattgtttc aattgcatat   2340

agcttggttt ccataacata gagcattggt tgactgttta cagaagactc actcaccagg   2400

ataaacattg ctgtatgtta cagtaaagct atctggagag aacacataaa tgattttggc   2460

ataccattag agaaaccatt tgtaaaactc aaatgaccac ataaagctta tcaaggagtc   2520

tagattggtt ttgttttata ccatatggga tgaagaaaat agaaatgtca gtagaactca   2580

ttgagggtgc tcttgccagc tgctgaaaat agaagttggc tactctcaga atttggttta   2640

aagctggaca gatttgcttt gttatagggt aaagctttgt ctaaagtcct cattttcttt   2700

taaaattgaa taaaatttct gtatacagat tc                                 2732


<210>  9814
<211>  674
<212>  PRT
<213>  Homo sapiens

<400>  9814

Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu Asn Pro 
1               5                   10                  15


Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met Asn Ser 
            20                  25                  30


Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu Tyr Val 
        35                  40                  45


Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val Arg Asp 
    50                  55                  60


Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys Asp His 
65                  70                  75                  80


Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser Pro Gln 
                85                  90                  95


Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile Gln Arg 
            100                 105                 110


Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala Ala Gly 
        115                 120                 125


Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln Thr His 
    130                 135                 140


Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly Gln Lys 
145                 150                 155                 160


Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val Tyr Leu 
                165                 170                 175


Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp Phe Phe 
            180                 185                 190


Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr Gly Pro 
        195                 200                 205


Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn Glu Ala 
    210                 215                 220


Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly Asn Arg 
225                 230                 235                 240


Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu Lys Ile 
                245                 250                 255


Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln Arg Glu 
            260                 265                 270


Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val Cys Ala 
        275                 280                 285


His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val Leu Gln 
    290                 295                 300


Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val Leu Val 
305                 310                 315                 320


Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe Lys Asn 
                325                 330                 335


Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys Leu Asn 
            340                 345                 350


Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met Arg Glu 
        355                 360                 365


Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys Met Pro 
    370                 375                 380


Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly Leu Pro 
385                 390                 395                 400


Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu Pro Ser 
                405                 410                 415


Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro Gly Ala 
            420                 425                 430


Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu His Ala 
        435                 440                 445


Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro Phe Asn 
    450                 455                 460


Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro Ile Pro 
465                 470                 475                 480


Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro Gly Met 
                485                 490                 495


Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp Val Pro 
            500                 505                 510


Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly Phe Gly 
        515                 520                 525


Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly Gly Pro 
    530                 535                 540


Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro Gly His 
545                 550                 555                 560


Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly Pro Gly 
                565                 570                 575


Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser Ser Ser 
            580                 585                 590


Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro Phe Thr 
        595                 600                 605


Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln Val Ile 
    610                 615                 620


Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro Thr Gly 
625                 630                 635                 640


Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala Ala Val 
                645                 650                 655


Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys Leu Val 
            660                 665                 670


Leu Gly 



<210>  9815
<211>  3470
<212>  DNA
<213>  Homo sapiens

<400>  9815
ggccattttg tgaagcggcg aaggaggtgg tggctgcgtt gggctccggg aagccgttcg     60

ggctggggct gtcggccgcg gggcggaggc actcgcgcgg ggggtaattc ggggtctggg    120

ttctggtgcc gcgcagcttt ccccggtgtg tgtggtttca gcgcagcatg gctgtggtca    180

tccgtttgca aggtctccca attgtggcgg ggaccatgga cattcgccac ttcttctctg    240

gattgaccat tcctgatggg ggcgtgcata ttgtaggggg tgaactgggt gaggctttca    300

tcgtttttgc cactgatgaa gatgcaaggc ttggtatgat gcgcacaggt ggtacaatta    360

aagggtcaaa agtaacacta ttgttgagta gtaagacgga aatgcagaat atgattgaac    420

tgagtcgtag gcgttttgaa actgccaact tagatatacc accagcaaat gccagtagat    480

caggaccacc acctagctca ggaatgagta gcagggtaaa cttgcccaca acagtatcca    540

actttaataa tccatcaccc agtgtagtta ctgccaccac ttctgttcat gaaagcaaca    600

aaaacataca gacattttcc acagccagcg taggaacagc tcctccaaat atgggggctt    660

cctttgggag cccaacgttt agctcaactg ttccaagcac agcctctcca atgaacacag    720

tcccgccgcc accaattcct ccaattccag cgatgccatc tctgccacca atgccatcca    780

ttcccccaat tccagttcct cctccagtac ctacattgcc tcctgtgcct cctgtgcccc    840

cgattccccc agttccttct gtgccaccca tgaccccact gccacccatg tcgggcatgc    900

cgcccttgaa tccgccacct gtggcacctc tacctgctgg aatgaatggc tctggagcac    960

ctatgaattt gaacaataat ctgaatccta tgtttcttgg tccgttgaat cctgttaacc   1020

ctatccagat gaactctcag agcagtgtga agccactccc catcaaccct gatgatctgt   1080

atgtcagtgt gcatggaatg cccttttctg caatggaaaa tgatgtcaga gatttttttc   1140

atgggctccg tgttgatgca gtgcatttgt tgaaagatca tgtaggtcga aataatggga   1200

atggattggt taagtttctc tcccctcaag atacatttga agctttgaaa cgaaacagaa   1260

tgctgatgat tcaacgctat gtggaagtta gccctgccac agaaagacag tgggtagctg   1320

ctggaggcca tatcactttt aagcaaaata tgggaccttc tggacaaact catccccctc   1380

ctcagacact tcccaggtca aaatcgccca gtgggcagaa aagatcaagg tcaagatcac   1440

cacatgaggc tggtttttgt gtttacttga aagggctacc atttgaagca gaaaacaaac   1500

atgtcattga tttttttaaa aagctggata ttgtggaaga tagtatttat atagcttatg   1560

gacccaatgg gaaagcaact ggcgaaggct ttgtagagtt cagaaatgag gctgactata   1620

aggctgctct gtgtcgtcat aaacagtaca tgggcaatcg ctttattcaa gttcatccaa   1680

ttactaagaa aggtatgcta gaaaagatag atatgattcg aaaaagactg cagaacttca   1740

gctatgacca gagggaaatg atactaaatc cagaggggga tgtcaactct gccaaagtct   1800

gtgcccacat aacaaatatt ccattcagca ttacaaagat ggatgttctt cagttcctag   1860

aaggaatccc agtggatgaa aatgctgtac atgttcttgt tgataacaat gggcaaggtc   1920

taggacaggc attggttcag tttaaaaatg aagatgatgc acgtaagtct gaacgcttac   1980

accgtaaaaa acttaatggg agagaagctt ttgttcatgt agttacccta gaagatatga   2040

gagagattga gaaaaatccc cctgcccaag gaaaaaaggg attaaagatg cctgtgccag   2100

gtaatcctgc agttccagga atgcccaatg cgggactgcc cggtgtggga ctgcccagtg   2160

caggacttcc cggtgcaggc ctgcccagca caggactgcc tggttcagca ataaccagtg   2220

caggactgcc tggtgcggga atgcccagtg caggaatacc tagtgcagga ggtgaagagc   2280

atgccttcct gactgtagga tcaaaggaag ccaataatgg gcctccattt aactttcctg   2340

gtaattttgg tggatcaaat gcctttgggc caccaatccc tcctccagga ttaggaggcg   2400

gggcctttgg tgatgctagg cctggtatgc cttcagttgg aaacagtggt ttgcctggtc   2460

taggactgga tgttccgggt tttggaggtg gaccaaacaa tttaagtggg ccatcgggat   2520

ttggaggggg ccctcagaat tttggaaatg gccctggtag cttaggcggt cccccggggt   2580

ttggaagtgg ccctcctggt cttggaagtg cccctgggca tttgggtggg ccaccagctt   2640

ttgggcctgg ccccggcccc ggccccggcc ctggcccaat ccatattggt ggtccccctg   2700

gctttgcatc tagttctgga aaaccaggac cgacagtaat taaagtgcaa aacatgccct   2760

ttactgtgtc tattgatgag attttagatt tcttttatgg ctatcaagta atcccaggct   2820

cagtgtgttt aaaatacaat gaaaaaggta tgcccacagg tgaagccatg gtggcctttg   2880

agtctcggga tgaagccaca gctgctgtca ttgacttaaa tgacaggcct ataggttcaa   2940

gaaaagtaaa acttgtatta gggtagccat tcacatcatt ttttataggg tagatcttca   3000

tattgctgtg attaatgcat ccagattgtt ttcctagtat ttccaggtta gaacctgtgg   3060

attgtttcaa ttgcatatag cttggtttcc ataacataga gcattggttg actgtttaca   3120

gaagactcac tcaccaggat aaacattgct gtatgttaca gtaaagctat ctggagagaa   3180

cacataaatg attttggcat accattagag aaaccatttg taaaactcaa atgaccacat   3240

aaagcttatc aaggagtcta gattggtttt gttttatacc atatgggatg aagaaaatag   3300

aaatgtcagt agaactcatt gagggtgctc ttgccagctg ctgaaaatag aagttggcta   3360

ctctcagaat ttggtttaaa gctggacaga tttgctttgt tatagggtaa agctttgtct   3420

aaagtcctca ttttctttta aaattgaata aaatttctgt atacagattc              3470


<210>  9816
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9816

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9817
<211>  2453
<212>  DNA
<213>  Homo sapiens

<400>  9817
ggaacgcgga gccgctgagc gggccgacgg ccattttgtg aagcggcgaa ggaggtggtg     60

gctgcgttgg gctccgggaa gccgttcggg ctggggctgt cggccgcggg gcggaggcac    120

tcgcgcgggg gtctaaaagt tggttttaat tggttgccca caggattgac ttggcctcta    180

cttcttgtta aggaaattca tctcttgttt tatcaggtgt gtgtggtttc agcgcagcat    240

ggctgtggtc atccgtttgc aaggtctccc aattgtggcg gggaccatgg acattcgcca    300

cttcttctct ggattgacca ttcctgatgg gggcgtgcat attgtagggg gtgaactggg    360

tgaggctttc atcgtttttg ccactgatga agatgcaagg cttggtatga tgcgcacagg    420

tggtacaatt aaagggtcaa aagtaacact attgttgagt agtaagacgg aaatgcagaa    480

tatgattgaa ctgatttttt aaaaagctgg atattgtgga agatagtatt tatatagctt    540

atggacccaa tgggaaagca actggcgaag gctttgtaga gttcagaaat gaggctgact    600

ataaggctgc tctgtgtcgt cataaacagt acatgggcaa tcgctttatt caagttcatc    660

caattactaa gaaaggtatg ctagaaaaga tagatatgat tcgaaaaaga ctgcagaact    720

tcagctatga ccagagggaa atgatactaa atccagaggg ggatgtcaac tctgccaaag    780

tctgtgccca cataacaaat attccattca gcattacaaa gatggatgtt cttcagttcc    840

tagaaggaat cccagtggat gaaaatgctg tacatgttct tgttgataac aatgggcaag    900

gtctaggaca ggcattggtt cagtttaaaa atgaagatga tgcacgtaag tctgaacgct    960

tacaccgtaa aaaacttaat gggagagaag cttttgttca tgtagttacc ctagaagata   1020

tgagagagat tgagaaaaat ccccctgccc aaggaaaaaa gggattaaag atgcctgtgc   1080

caggtaatcc tgcagttcca ggaatgccca atgcgggact gcccggtgtg ggactgccca   1140

gtgcaggact tcccggtgca ggcctgccca gcacaggact gcctggttca gcaataacca   1200

gtgcaggact gcctggtgcg ggaatgccca gtgcaggaat acctagtgca ggaggtgaag   1260

agcatgcctt cctgactgta ggatcaaagg aagccaataa tgggcctcca tttaactttc   1320

ctggtaattt tggtggatca aatgcctttg ggccaccaat ccctcctcca ggattaggag   1380

gcggggcctt tggtgatgct aggcctggta tgccttcagt tggaaacagt ggtttgcctg   1440

gtctaggact ggatgttccg ggttttggag gtggaccaaa caatttaagt gggccatcgg   1500

gatttggagg gggccctcag aattttggaa atggccctgg tagcttaggc ggtcccccgg   1560

ggtttggaag tggccctcct ggtcttggaa gtgcccctgg gcatttgggt gggccaccag   1620

cttttgggcc tggccccggc cccggccccg gccctggccc aatccatatt ggtggtcccc   1680

ctggctttgc atctagttct ggaaaaccag gaccgacagt aattaaagtg caaaacatgc   1740

cctttactgt gtctattgat gagattttag atttctttta tggctatcaa gtaatcccag   1800

gctcagtgtg tttaaaatac aatgaaaaag gtatgcccac aggtgaagcc atggtggcct   1860

ttgagtctcg ggatgaagcc acagctgctg tcattgactt aaatgacagg cctataggtt   1920

caagaaaagt aaaacttgta ttagggtagc cattcacatc attttttata gggtagatct   1980

tcatattgct gtgattaatg catccagatt gttttcctag tatttccagg ttagaacctg   2040

tggattgttt caattgcata tagcttggtt tccataacat agagcattgg ttgactgttt   2100

acagaagact cactcaccag gataaacatt gctgtatgtt acagtaaagc tatctggaga   2160

gaacacataa atgattttgg cataccatta gagaaaccat ttgtaaaact caaatgacca   2220

cataaagctt atcaaggagt ctagattggt tttgttttat accatatggg atgaagaaaa   2280

tagaaatgtc agtagaactc attgagggtg ctcttgccag ctgctgaaaa tagaagttgg   2340

ctactctcag aatttggttt aaagctggac agatttgctt tgttataggg taaagctttg   2400

tctaaagtcc tcattttctt ttaaaattga ataaaatttc tgtatacaga ttc          2453


<210>  9818
<211>  87
<212>  PRT
<213>  Homo sapiens

<400>  9818

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ile Phe 
                85


<210>  9819
<211>  3542
<212>  DNA
<213>  Homo sapiens

<400>  9819
tggaacgcgg agccgctgag cgggccgacg gccattttgt gaagcggcga aggaggtggt     60

ggctgcgttg ggctccggga agccgttcgg gctggggctg tcggccgcgg ggcggaggca    120

ctcgcgcggg ggtctaaaag ttggttttaa ttggttgccc acaggattga cttggcctct    180

acttcttgtt aaggaaattc atctcttgtt ttatcaggtg tgtgtggttt cagcgcagca    240

tggctgtggt catccgtttg caaggtctcc caattgtggc ggggaccatg gacattcgcc    300

acttcttctc tggattgacc attcctgatg ggggcgtgca tattgtaggg ggtgaactgg    360

gtgaggcttt catcgttttt gccactgatg aagatgcaag gcttggtatg atgcgcacag    420

gtggtacaat taaagggtca aaagtaacac tattgttgag tagtaagacg gaaatgcaga    480

atatgattga actgagtcgt aggcgttttg aaactgccaa cttagatata ccaccagcaa    540

atgccagtag atcaggacca ccacctagct caggaatgag tagcagggta aacttgccca    600

caacagtatc caactttaat aatccatcac ccagtgtagt tactgccacc acttctgttc    660

atgaaagcaa caaaaacata cagacatttt ccacagccag cgtaggaaca gctcctccaa    720

atatgggggc ttcctttggg agcccaacgt ttagctcaac tgttccaagc acagcctctc    780

caatgaacac agtcccgccg ccaccaattc ctccaattcc agcgatgcca tctctgccac    840

caatgccatc cattccccca attccagttc ctcctccagt acctacattg cctcctgtgc    900

ctcctgtgcc cccgattccc ccagttcctt ctgtgccacc catgacccca ctgccaccca    960

tgtcgggcat gccgcccttg aatccgccac ctgtggcacc tctacctgct ggaatgaatg   1020

gctctggagc acctatgaat ttgaacaata atctgaatcc tatgtttctt ggtccgttga   1080

atcctgttaa ccctatccag atgaactctc agagcagtgt gaagccactc cccatcaacc   1140

ctgatgatct gtatgtcagt gtgcatggaa tgcccttttc tgcaatggaa aatgatgtca   1200

gagatttttt tcatgggctc cgtgttgatg cagtgcattt gttgaaagat catgtaggtc   1260

gaaataatgg gaatggattg gttaagtttc tctcccctca agatacattt gaagctttga   1320

aacgaaacag aatgctgatg attcaacgct atgtggaagt tagccctgcc acagaaagac   1380

agtgggtagc tgctggaggc catatcactt ttaagcaaaa tatgggacct tctggacaaa   1440

ctcatccccc tcctcagaca cttcccaggt caaaatcgcc cagtgggcag aaaagatcaa   1500

ggtcaagatc accacatgag gctggttttt gtgtttactt gaaagggcta ccatttgaag   1560

cagaaaacaa acatgtcatt gattttttta aaaagctgga tattgtggaa gatagtattt   1620

atatagctta tggacccaat gggaaagcaa ctggcgaagg ctttgtagag ttcagaaatg   1680

aggctgacta taaggctgct ctgtgtcgtc ataaacagta catgggcaat cgctttattc   1740

aagttcatcc aattactaag aaaggtatgc tagaaaagat agatatgatt cgaaaaagac   1800

tgcagaactt cagctatgac cagagggaaa tgatactaaa tccagagggg gatgtcaact   1860

ctgccaaagt ctgtgcccac ataacaaata ttccattcag cattacaaag atggatgttc   1920

ttcagttcct agaaggaatc ccagtggatg aaaatgctgt acatgttctt gttgataaca   1980

atgggcaagg tctaggacag gcattggttc agtttaaaaa tgaagatgat gcacgtaagt   2040

ctgaacgctt acaccgtaaa aaacttaatg ggagagaagc ttttgttcat gtagttaccc   2100

tagaagatat gagagagatt gagaaaaatc cccctgccca aggaaaaaag ggattaaaga   2160

tgcctgtgcc aggtaatcct gcagttccag gaatgcccaa tgcgggactg cccggtgtgg   2220

gactgcccag tgcaggactt cccggtgcag gcctgcccag cacaggactg cctggttcag   2280

caataaccag tgcaggactg cctggtgcgg gaatgcccag tgcaggaata cctagtgcag   2340

gaggtgaaga gcatgccttc ctgactgtag gatcaaagga agccaataat gggcctccat   2400

ttaactttcc tggtaatttt ggtggatcaa atgcctttgg gccaccaatc cctcctccag   2460

gattaggagg cggggccttt ggtgatgcta ggcctggtat gccttcagtt ggaaacagtg   2520

gtttgcctgg tctaggactg gatgttccgg gttttggagg tggaccaaac aatttaagtg   2580

ggccatcggg atttggaggg ggccctcaga attttggaaa tggccctggt agcttaggcg   2640

gtcccccggg gtttggaagt ggccctcctg gtcttggaag tgcccctggg catttgggtg   2700

ggccaccagc ttttgggcct ggccccggcc ccggccccgg ccctggccca atccatattg   2760

gtggtccccc tggctttgca tctagttctg gaaaaccagg accgacagta attaaagtgc   2820

aaaacatgcc ctttactgtg tctattgatg agattttaga tttcttttat ggctatcaag   2880

taatcccagg ctcagtgtgt ttaaaataca atgaaaaagg tatgcccaca ggtgaagcca   2940

tggtggcctt tgagtctcgg gatgaagcca cagctgctgt cattgactta aatgacaggc   3000

ctataggttc aagaaaagta aaacttgtat tagggtagcc attcacatca ttttttatag   3060

ggtagatctt catattgctg tgattaatgc atccagattg ttttcctagt atttccaggt   3120

tagaacctgt ggattgtttc aattgcatat agcttggttt ccataacata gagcattggt   3180

tgactgttta cagaagactc actcaccagg ataaacattg ctgtatgtta cagtaaagct   3240

atctggagag aacacataaa tgattttggc ataccattag agaaaccatt tgtaaaactc   3300

aaatgaccac ataaagctta tcaaggagtc tagattggtt ttgttttata ccatatggga   3360

tgaagaaaat agaaatgtca gtagaactca ttgagggtgc tcttgccagc tgctgaaaat   3420

agaagttggc tactctcaga atttggttta aagctggaca gatttgcttt gttatagggt   3480

aaagctttgt ctaaagtcct cattttcttt taaaattgaa taaaatttct gtatacagat   3540

tc                                                                  3542


<210>  9820
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9820

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9821
<211>  3588
<212>  DNA
<213>  Homo sapiens

<400>  9821
cttctggaac gcggagccgc tgagcgggcc gacggccatt ttgtgaagcg gcgaaggagg     60

tggtggctgc gttgggctcc gggaagccgt tcgggctggg gctgtcggcc gcggggcgga    120

ggcactcgcg cggggggtaa ttcggggtct gggttctggt gccgcgcagc tttccccgtc    180

taaaagttgg ttttaattgg ttgcccacag gattgacttg gcctctactt cttgttaagg    240

aaattcatct cttgttttat caggtgtgtg tggtttcagc gcagcatggc tgtggtcatc    300

cgtttgcaag gtctcccaat tgtggcgggg accatggaca ttcgccactt cttctctgga    360

ttgaccattc ctgatggggg cgtgcatatt gtagggggtg aactgggtga ggctttcatc    420

gtttttgcca ctgatgaaga tgcaaggctt ggtatgatgc gcacaggtgg tacaattaaa    480

gggtcaaaag taacactatt gttgagtagt aagacggaaa tgcagaatat gattgaactg    540

agtcgtaggc gttttgaaac tgccaactta gatataccac cagcaaatgc cagtagatca    600

ggaccaccac ctagctcagg aatgagtagc agggtaaact tgcccacaac agtatccaac    660

tttaataatc catcacccag tgtagttact gccaccactt ctgttcatga aagcaacaaa    720

aacatacaga cattttccac agccagcgta ggaacagctc ctccaaatat gggggcttcc    780

tttgggagcc caacgtttag ctcaactgtt ccaagcacag cctctccaat gaacacagtc    840

ccgccgccac caattcctcc aattccagcg atgccatctc tgccaccaat gccatccatt    900

cccccaattc cagttcctcc tccagtacct acattgcctc ctgtgcctcc tgtgcccccg    960

attcccccag ttccttctgt gccacccatg accccactgc cacccatgtc gggcatgccg   1020

cccttgaatc cgccacctgt ggcacctcta cctgctggaa tgaatggctc tggagcacct   1080

atgaatttga acaataatct gaatcctatg tttcttggtc cgttgaatcc tgttaaccct   1140

atccagatga actctcagag cagtgtgaag ccactcccca tcaaccctga tgatctgtat   1200

gtcagtgtgc atggaatgcc cttttctgca atggaaaatg atgtcagaga tttttttcat   1260

gggctccgtg ttgatgcagt gcatttgttg aaagatcatg taggtcgaaa taatgggaat   1320

ggattggtta agtttctctc ccctcaagat acatttgaag ctttgaaacg aaacagaatg   1380

ctgatgattc aacgctatgt ggaagttagc cctgccacag aaagacagtg ggtagctgct   1440

ggaggccata tcacttttaa gcaaaatatg ggaccttctg gacaaactca tccccctcct   1500

cagacacttc ccaggtcaaa atcgcccagt gggcagaaaa gatcaaggtc aagatcacca   1560

catgaggctg gtttttgtgt ttacttgaaa gggctaccat ttgaagcaga aaacaaacat   1620

gtcattgatt tttttaaaaa gctggatatt gtggaagata gtatttatat agcttatgga   1680

cccaatggga aagcaactgg cgaaggcttt gtagagttca gaaatgaggc tgactataag   1740

gctgctctgt gtcgtcataa acagtacatg ggcaatcgct ttattcaagt tcatccaatt   1800

actaagaaag gtatgctaga aaagatagat atgattcgaa aaagactgca gaacttcagc   1860

tatgaccaga gggaaatgat actaaatcca gagggggatg tcaactctgc caaagtctgt   1920

gcccacataa caaatattcc attcagcatt acaaagatgg atgttcttca gttcctagaa   1980

ggaatcccag tggatgaaaa tgctgtacat gttcttgttg ataacaatgg gcaaggtcta   2040

ggacaggcat tggttcagtt taaaaatgaa gatgatgcac gtaagtctga acgcttacac   2100

cgtaaaaaac ttaatgggag agaagctttt gttcatgtag ttaccctaga agatatgaga   2160

gagattgaga aaaatccccc tgcccaagga aaaaagggat taaagatgcc tgtgccaggt   2220

aatcctgcag ttccaggaat gcccaatgcg ggactgcccg gtgtgggact gcccagtgca   2280

ggacttcccg gtgcaggcct gcccagcaca ggactgcctg gttcagcaat aaccagtgca   2340

ggactgcctg gtgcgggaat gcccagtgca ggaataccta gtgcaggagg tgaagagcat   2400

gccttcctga ctgtaggatc aaaggaagcc aataatgggc ctccatttaa ctttcctggt   2460

aattttggtg gatcaaatgc ctttgggcca ccaatccctc ctccaggatt aggaggcggg   2520

gcctttggtg atgctaggcc tggtatgcct tcagttggaa acagtggttt gcctggtcta   2580

ggactggatg ttccgggttt tggaggtgga ccaaacaatt taagtgggcc atcgggattt   2640

ggagggggcc ctcagaattt tggaaatggc cctggtagct taggcggtcc cccggggttt   2700

ggaagtggcc ctcctggtct tggaagtgcc cctgggcatt tgggtgggcc accagctttt   2760

gggcctggcc ccggccccgg ccccggccct ggcccaatcc atattggtgg tccccctggc   2820

tttgcatcta gttctggaaa accaggaccg acagtaatta aagtgcaaaa catgcccttt   2880

actgtgtcta ttgatgagat tttagatttc ttttatggct atcaagtaat cccaggctca   2940

gtgtgtttaa aatacaatga aaaaggtatg cccacaggtg aagccatggt ggcctttgag   3000

tctcgggatg aagccacagc tgctgtcatt gacttaaatg acaggcctat aggttcaaga   3060

aaagtaaaac ttgtattagg gtagccattc acatcatttt ttatagggta gatcttcata   3120

ttgctgtgat taatgcatcc agattgtttt cctagtattt ccaggttaga acctgtggat   3180

tgtttcaatt gcatatagct tggtttccat aacatagagc attggttgac tgtttacaga   3240

agactcactc accaggataa acattgctgt atgttacagt aaagctatct ggagagaaca   3300

cataaatgat tttggcatac cattagagaa accatttgta aaactcaaat gaccacataa   3360

agcttatcaa ggagtctaga ttggttttgt tttataccat atgggatgaa gaaaatagaa   3420

atgtcagtag aactcattga gggtgctctt gccagctgct gaaaatagaa gttggctact   3480

ctcagaattt ggtttaaagc tggacagatt tgctttgtta tagggtaaag ctttgtctaa   3540

agtcctcatt ttcttttaaa attgaataaa atttctgtat acagattc                3588


<210>  9822
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9822

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9823
<211>  3456
<212>  DNA
<213>  Homo sapiens

<400>  9823
aaccacgccg ttcctccccc ttctggaacg cggagccgct gagcgggccg acggccattt     60

tgtgaagcgg cgaaggagga ttgacttggc ctctacttct tgttaaggaa attcatctct    120

tgttttatca ggtgtgtgtg gtttcagcgc agcatggctg tggtcatccg tttgcaaggt    180

ctcccaattg tggcggggac catggacatt cgccacttct tctctggatt gaccattcct    240

gatgggggcg tgcatattgt agggggtgaa ctgggtgagg ctttcatcgt ttttgccact    300

gatgaagatg caaggcttgg tatgatgcgc acaggtggta caattaaagg gtcaaaagta    360

acactattgt tgagtagtaa gacggaaatg cagaatatga ttgaactgag tcgtaggcgt    420

tttgaaactg ccaacttaga tataccacca gcaaatgcca gtagatcagg accaccacct    480

agctcaggaa tgagtagcag ggtaaacttg cccacaacag tatccaactt taataatcca    540

tcacccagtg tagttactgc caccacttct gttcatgaaa gcaacaaaaa catacagaca    600

ttttccacag ccagcgtagg aacagctcct ccaaatatgg gggcttcctt tgggagccca    660

acgtttagct caactgttcc aagcacagcc tctccaatga acacagtccc gccgccacca    720

attcctccaa ttccagcgat gccatctctg ccaccaatgc catccattcc cccaattcca    780

gttcctcctc cagtacctac attgcctcct gtgcctcctg tgcccccgat tcccccagtt    840

ccttctgtgc cacccatgac cccactgcca cccatgtcgg gcatgccgcc cttgaatccg    900

ccacctgtgg cacctctacc tgctggaatg aatggctctg gagcacctat gaatttgaac    960

aataatctga atcctatgtt tcttggtccg ttgaatcctg ttaaccctat ccagatgaac   1020

tctcagagca gtgtgaagcc actccccatc aaccctgatg atctgtatgt cagtgtgcat   1080

ggaatgccct tttctgcaat ggaaaatgat gtcagagatt tttttcatgg gctccgtgtt   1140

gatgcagtgc atttgttgaa agatcatgta ggtcgaaata atgggaatgg attggttaag   1200

tttctctccc ctcaagatac atttgaagct ttgaaacgaa acagaatgct gatgattcaa   1260

cgctatgtgg aagttagccc tgccacagaa agacagtggg tagctgctgg aggccatatc   1320

acttttaagc aaaatatggg accttctgga caaactcatc cccctcctca gacacttccc   1380

aggtcaaaat cgcccagtgg gcagaaaaga tcaaggtcaa gatcaccaca tgaggctggt   1440

ttttgtgttt acttgaaagg gctaccattt gaagcagaaa acaaacatgt cattgatttt   1500

tttaaaaagc tggatattgt ggaagatagt atttatatag cttatggacc caatgggaaa   1560

gcaactggcg aaggctttgt agagttcaga aatgaggctg actataaggc tgctctgtgt   1620

cgtcataaac agtacatggg caatcgcttt attcaagttc atccaattac taagaaaggt   1680

atgctagaaa agatagatat gattcgaaaa agactgcaga acttcagcta tgaccagagg   1740

gaaatgatac taaatccaga gggggatgtc aactctgcca aagtctgtgc ccacataaca   1800

aatattccat tcagcattac aaagatggat gttcttcagt tcctagaagg aatcccagtg   1860

gatgaaaatg ctgtacatgt tcttgttgat aacaatgggc aaggtctagg acaggcattg   1920

gttcagttta aaaatgaaga tgatgcacgt aagtctgaac gcttacaccg taaaaaactt   1980

aatgggagag aagcttttgt tcatgtagtt accctagaag atatgagaga gattgagaaa   2040

aatccccctg cccaaggaaa aaagggatta aagatgcctg tgccaggtaa tcctgcagtt   2100

ccaggaatgc ccaatgcggg actgcccggt gtgggactgc ccagtgcagg acttcccggt   2160

gcaggcctgc ccagcacagg actgcctggt tcagcaataa ccagtgcagg actgcctggt   2220

gcgggaatgc ccagtgcagg aatacctagt gcaggaggtg aagagcatgc cttcctgact   2280

gtaggatcaa aggaagccaa taatgggcct ccatttaact ttcctggtaa ttttggtgga   2340

tcaaatgcct ttgggccacc aatccctcct ccaggattag gaggcggggc ctttggtgat   2400

gctaggcctg gtatgccttc agttggaaac agtggtttgc ctggtctagg actggatgtt   2460

ccgggttttg gaggtggacc aaacaattta agtgggccat cgggatttgg agggggccct   2520

cagaattttg gaaatggccc tggtagctta ggcggtcccc cggggtttgg aagtggccct   2580

cctggtcttg gaagtgcccc tgggcatttg ggtgggccac cagcttttgg gcctggcccc   2640

ggccccggcc ccggccctgg cccaatccat attggtggtc cccctggctt tgcatctagt   2700

tctggaaaac caggaccgac agtaattaaa gtgcaaaaca tgccctttac tgtgtctatt   2760

gatgagattt tagatttctt ttatggctat caagtaatcc caggctcagt gtgtttaaaa   2820

tacaatgaaa aaggtatgcc cacaggtgaa gccatggtgg cctttgagtc tcgggatgaa   2880

gccacagctg ctgtcattga cttaaatgac aggcctatag gttcaagaaa agtaaaactt   2940

gtattagggt agccattcac atcatttttt atagggtaga tcttcatatt gctgtgatta   3000

atgcatccag attgttttcc tagtatttcc aggttagaac ctgtggattg tttcaattgc   3060

atatagcttg gtttccataa catagagcat tggttgactg tttacagaag actcactcac   3120

caggataaac attgctgtat gttacagtaa agctatctgg agagaacaca taaatgattt   3180

tggcatacca ttagagaaac catttgtaaa actcaaatga ccacataaag cttatcaagg   3240

agtctagatt ggttttgttt tataccatat gggatgaaga aaatagaaat gtcagtagaa   3300

ctcattgagg gtgctcttgc cagctgctga aaatagaagt tggctactct cagaatttgg   3360

tttaaagctg gacagatttg ctttgttata gggtaaagct ttgtctaaag tcctcatttt   3420

cttttaaaat tgaataaaat ttctgtatac agattc                             3456


<210>  9824
<211>  932
<212>  PRT
<213>  Homo sapiens

<400>  9824

Met Ala Val Val Ile Arg Leu Gln Gly Leu Pro Ile Val Ala Gly Thr 
1               5                   10                  15


Met Asp Ile Arg His Phe Phe Ser Gly Leu Thr Ile Pro Asp Gly Gly 
            20                  25                  30


Val His Ile Val Gly Gly Glu Leu Gly Glu Ala Phe Ile Val Phe Ala 
        35                  40                  45


Thr Asp Glu Asp Ala Arg Leu Gly Met Met Arg Thr Gly Gly Thr Ile 
    50                  55                  60


Lys Gly Ser Lys Val Thr Leu Leu Leu Ser Ser Lys Thr Glu Met Gln 
65                  70                  75                  80


Asn Met Ile Glu Leu Ser Arg Arg Arg Phe Glu Thr Ala Asn Leu Asp 
                85                  90                  95


Ile Pro Pro Ala Asn Ala Ser Arg Ser Gly Pro Pro Pro Ser Ser Gly 
            100                 105                 110


Met Ser Ser Arg Val Asn Leu Pro Thr Thr Val Ser Asn Phe Asn Asn 
        115                 120                 125


Pro Ser Pro Ser Val Val Thr Ala Thr Thr Ser Val His Glu Ser Asn 
    130                 135                 140


Lys Asn Ile Gln Thr Phe Ser Thr Ala Ser Val Gly Thr Ala Pro Pro 
145                 150                 155                 160


Asn Met Gly Ala Ser Phe Gly Ser Pro Thr Phe Ser Ser Thr Val Pro 
                165                 170                 175


Ser Thr Ala Ser Pro Met Asn Thr Val Pro Pro Pro Pro Ile Pro Pro 
            180                 185                 190


Ile Pro Ala Met Pro Ser Leu Pro Pro Met Pro Ser Ile Pro Pro Ile 
        195                 200                 205


Pro Val Pro Pro Pro Val Pro Thr Leu Pro Pro Val Pro Pro Val Pro 
    210                 215                 220


Pro Ile Pro Pro Val Pro Ser Val Pro Pro Met Thr Pro Leu Pro Pro 
225                 230                 235                 240


Met Ser Gly Met Pro Pro Leu Asn Pro Pro Pro Val Ala Pro Leu Pro 
                245                 250                 255


Ala Gly Met Asn Gly Ser Gly Ala Pro Met Asn Leu Asn Asn Asn Leu 
            260                 265                 270


Asn Pro Met Phe Leu Gly Pro Leu Asn Pro Val Asn Pro Ile Gln Met 
        275                 280                 285


Asn Ser Gln Ser Ser Val Lys Pro Leu Pro Ile Asn Pro Asp Asp Leu 
    290                 295                 300


Tyr Val Ser Val His Gly Met Pro Phe Ser Ala Met Glu Asn Asp Val 
305                 310                 315                 320


Arg Asp Phe Phe His Gly Leu Arg Val Asp Ala Val His Leu Leu Lys 
                325                 330                 335


Asp His Val Gly Arg Asn Asn Gly Asn Gly Leu Val Lys Phe Leu Ser 
            340                 345                 350


Pro Gln Asp Thr Phe Glu Ala Leu Lys Arg Asn Arg Met Leu Met Ile 
        355                 360                 365


Gln Arg Tyr Val Glu Val Ser Pro Ala Thr Glu Arg Gln Trp Val Ala 
    370                 375                 380


Ala Gly Gly His Ile Thr Phe Lys Gln Asn Met Gly Pro Ser Gly Gln 
385                 390                 395                 400


Thr His Pro Pro Pro Gln Thr Leu Pro Arg Ser Lys Ser Pro Ser Gly 
                405                 410                 415


Gln Lys Arg Ser Arg Ser Arg Ser Pro His Glu Ala Gly Phe Cys Val 
            420                 425                 430


Tyr Leu Lys Gly Leu Pro Phe Glu Ala Glu Asn Lys His Val Ile Asp 
        435                 440                 445


Phe Phe Lys Lys Leu Asp Ile Val Glu Asp Ser Ile Tyr Ile Ala Tyr 
    450                 455                 460


Gly Pro Asn Gly Lys Ala Thr Gly Glu Gly Phe Val Glu Phe Arg Asn 
465                 470                 475                 480


Glu Ala Asp Tyr Lys Ala Ala Leu Cys Arg His Lys Gln Tyr Met Gly 
                485                 490                 495


Asn Arg Phe Ile Gln Val His Pro Ile Thr Lys Lys Gly Met Leu Glu 
            500                 505                 510


Lys Ile Asp Met Ile Arg Lys Arg Leu Gln Asn Phe Ser Tyr Asp Gln 
        515                 520                 525


Arg Glu Met Ile Leu Asn Pro Glu Gly Asp Val Asn Ser Ala Lys Val 
    530                 535                 540


Cys Ala His Ile Thr Asn Ile Pro Phe Ser Ile Thr Lys Met Asp Val 
545                 550                 555                 560


Leu Gln Phe Leu Glu Gly Ile Pro Val Asp Glu Asn Ala Val His Val 
                565                 570                 575


Leu Val Asp Asn Asn Gly Gln Gly Leu Gly Gln Ala Leu Val Gln Phe 
            580                 585                 590


Lys Asn Glu Asp Asp Ala Arg Lys Ser Glu Arg Leu His Arg Lys Lys 
        595                 600                 605


Leu Asn Gly Arg Glu Ala Phe Val His Val Val Thr Leu Glu Asp Met 
    610                 615                 620


Arg Glu Ile Glu Lys Asn Pro Pro Ala Gln Gly Lys Lys Gly Leu Lys 
625                 630                 635                 640


Met Pro Val Pro Gly Asn Pro Ala Val Pro Gly Met Pro Asn Ala Gly 
                645                 650                 655


Leu Pro Gly Val Gly Leu Pro Ser Ala Gly Leu Pro Gly Ala Gly Leu 
            660                 665                 670


Pro Ser Thr Gly Leu Pro Gly Ser Ala Ile Thr Ser Ala Gly Leu Pro 
        675                 680                 685


Gly Ala Gly Met Pro Ser Ala Gly Ile Pro Ser Ala Gly Gly Glu Glu 
    690                 695                 700


His Ala Phe Leu Thr Val Gly Ser Lys Glu Ala Asn Asn Gly Pro Pro 
705                 710                 715                 720


Phe Asn Phe Pro Gly Asn Phe Gly Gly Ser Asn Ala Phe Gly Pro Pro 
                725                 730                 735


Ile Pro Pro Pro Gly Leu Gly Gly Gly Ala Phe Gly Asp Ala Arg Pro 
            740                 745                 750


Gly Met Pro Ser Val Gly Asn Ser Gly Leu Pro Gly Leu Gly Leu Asp 
        755                 760                 765


Val Pro Gly Phe Gly Gly Gly Pro Asn Asn Leu Ser Gly Pro Ser Gly 
    770                 775                 780


Phe Gly Gly Gly Pro Gln Asn Phe Gly Asn Gly Pro Gly Ser Leu Gly 
785                 790                 795                 800


Gly Pro Pro Gly Phe Gly Ser Gly Pro Pro Gly Leu Gly Ser Ala Pro 
                805                 810                 815


Gly His Leu Gly Gly Pro Pro Ala Phe Gly Pro Gly Pro Gly Pro Gly 
            820                 825                 830


Pro Gly Pro Gly Pro Ile His Ile Gly Gly Pro Pro Gly Phe Ala Ser 
        835                 840                 845


Ser Ser Gly Lys Pro Gly Pro Thr Val Ile Lys Val Gln Asn Met Pro 
    850                 855                 860


Phe Thr Val Ser Ile Asp Glu Ile Leu Asp Phe Phe Tyr Gly Tyr Gln 
865                 870                 875                 880


Val Ile Pro Gly Ser Val Cys Leu Lys Tyr Asn Glu Lys Gly Met Pro 
                885                 890                 895


Thr Gly Glu Ala Met Val Ala Phe Glu Ser Arg Asp Glu Ala Thr Ala 
            900                 905                 910


Ala Val Ile Asp Leu Asn Asp Arg Pro Ile Gly Ser Arg Lys Val Lys 
        915                 920                 925


Leu Val Leu Gly 
    930


<210>  9825
<211>  1253
<212>  DNA
<213>  Homo sapiens

<400>  9825
agaattgaag atgctccaaa ggccactaag tgtttggctg cccttcaggc tggtgcagat     60

ggtgcattac gtcctgggga atgcctgcac ctctgcatcc ctggagccct cttatgtgct    120

tagagcaatt ggcactgatg aggatttagc gcactcttct atcaggtttg gaattggccg    180

cttcactaca gaggaggaag tggactacac agtggagaaa tgcattcagc atgtgaagcg    240

tcttcgagaa atgagccctc tctgggagat ggttcaggat ggcattgacc tcaagagcat    300

caagtggacc caacactaga agaatagggc cctgactttg tgctggtctg gcccctcctg    360

cctcaccaac ccgtgcacaa ccagacacct tgttacacct agtggatgct ctagattggt    420

atagaccagt tgacttcagc atcagtccac ctctatgaca gaaacacaag aaaactgtct    480

ttccctagct tcagttcctt gggtgtggag cactccccat ttcttctcgg gtcttaaagt    540

gtgtggacat tttcatcccg aagccataga gacatttgct gtcatattgc tgctgggcac    600

atctgtgctc ttggtgagga gagcaagagg aaccagaaga agtctctttg gtcagggacc    660

atgatgctct acatggacat ttgagtcttc gtcttctgct gctgctcggc tggaccagct    720

tctttaacag caagcataat ccacttcaat gtaatatttt ctgtagctcc aaaggctatc    780

tcttcatatt gactgcagac agactgaatg gacagtttct tagagggctt gtctcctttc    840

tacccttgtc ctctttcctt tcctttgacc taatggagct agaaatatgt ctgtgactcc    900

accagttatt ctaataattt gttttcttga aaattgttaa tttcaagact ggagaaataa    960

actcaccttc tatttactct gtgactttat gagaggttga gggaaaagtg gaagctgtac   1020

ttgggaattg tggagaagac cgccactcca tctgatttgc ataaatgact cagtgggctt   1080

ttgtatctct tcatttaaga attatttgaa tgcctgccag gagccagatt tgttctgggt   1140

attaggaata cactggttaa caggaccaaa aaagaccctg ccctcactga gttttaaatt   1200

ttagtggaga gatggaaaat aattaaacaa ataaacaatg ttatagattg tga          1253


<210>  9826
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  9826

Met Leu Gln Arg Pro Leu Ser Val Trp Leu Pro Phe Arg Leu Val Gln 
1               5                   10                  15


Met Val His Tyr Val Leu Gly Asn Ala Cys Thr Ser Ala Ser Leu Glu 
            20                  25                  30


Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr Asp Glu Asp Leu Ala His 
        35                  40                  45


Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe Thr Thr Glu Glu Glu Val 
    50                  55                  60


Asp Tyr Thr Val Glu Lys Cys Ile Gln His Val Lys Arg Leu Arg Glu 
65                  70                  75                  80


Met Ser Pro Leu Trp Glu Met Val Gln Asp Gly Ile Asp Leu Lys Ser 
                85                  90                  95


Ile Lys Trp Thr Gln His 
            100


<210>  9827
<211>  2929
<212>  DNA
<213>  Homo sapiens

<400>  9827
cagcctccct agtagctggg attacaggca tgtgccacca tgcctggcta attttgtatt     60

tttagtggag aaggggtttc tccatgttgg tcaggctggt ctcaaactcc cgaactcagg    120

tgatccaccc acctcagcct cccaaagtgc tggtattaca ggcgtgagcc actgcgcccg    180

gccaatacat ctttgttttt tcaagctaaa gtacagactt ttttttggat ttcaccagtt    240

ttgtaacaat gtatcttgga gattttatgg tgtcagttca gaacaagctt cttctttttt    300

tttttttttt ttttgggaga cagagtcttg ctccatcact caggctggag tgcagtggct    360

tgatctcagc tcactgcaac ctctaccacc tgggttcatc tcatgtctca gcctcctgag    420

tagctgggat tacatgtgcc tgctaccacg cttggctaat ctttgtattt ttagtagaga    480

gagggtttca ccatgttgac caggctggtt tctaacttct gatctcaggt gatccgcccg    540

ccttgacctc ccacagttgg gattataggc gtgaaccacc acacccggcc ccctcattct    600

tttatacacc tgcttggtat ttcattgtat ggacatgcca taatctattt gaccattacc    660

ctgatgatgg acatctaagt tgttcccagt atttttgcta ttatgaataa tactgtaatg    720

tatgatggca tttcatatag catagggagc tactttaaac cattttgatc attactcctt    780

ctggcattta tcttccagat gttaaatatt ttactaaata ctatgctttt actgctgttt    840

cttcttttcc ttaacgtttt ttatttagaa aaatttcatg cttacagaaa agttgaagta    900

atattttgat ccctttggaa agaaatattt tgttttatct acttttctct ctttctgttt    960

tttgtaacaa attttgtttc ccaggggttg gtgccatcta catccgtcgc cggccccgtg   1020

tgcgtgtgga ggccctgcag agtggagggg ggcaggagcg gggtatgcgg tctgggacag   1080

tgcccacacc cttagtggtg gggctggggg ctgcgtgtga ggtggcacag caagagatgg   1140

aggtatgggg agagcagttc cctcccacaa cttcttcccc tgtgctgggt ctcctattta   1200

gaggcttctc agcatgactg aggcagatct ctgcagggag agagggctta agaaaactct   1260

tccttgtcct ggtgctgctg gcaccttgtt ctgagggaga cattatgggc ttcaaaaccc   1320

atggcctttt agtagttatc agctcattta tttctggata agtaaatgaa ccctgtgtcc   1380

agttatcaag cgccttttgc ataccaggca ctatgctcag tactggagat acagtggtcc   1440

ccatgagtac ataggatgat aggtggggct gatacatagt cacttccagt tataggagaa   1500

gggcttctca aactgtcttt ctgagctggt taatggttac tgcctaatcc ttccttgcct   1560

gctccttagt atgaccacaa gcgaatctca aagttgtcag agcggctgat acagaatata   1620

atgaagagcc ttccagatgt ggtgatgaat ggggacccta agcaccatta tcccggctgt   1680

atcaacctct cctttgcata tgtggaaggg gaaagtctgc tgatggcact gaaggacgtt   1740

gccttatcct cagggagtgc ctgcacctct gcatccctgg agccctctta tgtgcttaga   1800

gcaattggca ctgatgagga tttagcgcac tcttctatca ggtttggaat tggccgcttc   1860

actacagagg aggaagtgga ctacacagtg gagaaatgca ttcagcatgt gaagcgtctt   1920

cgagaaatga gccctctctg ggagatggtt caggatggca ttgacctcaa gagcatcaag   1980

tggacccaac actagaagaa tagggccctg actttgtgct ggtctggccc ctcctgcctc   2040

accaacccgt gcacaaccag acaccttgtt acacctagtg gatgctctag attggtatag   2100

accagttgac ttcagcatca gtccacctct atgacagaaa cacaagaaaa ctgtctttcc   2160

ctagcttcag ttccttgggt gtggagcact ccccatttct tctcgggtct taaagtgtgt   2220

ggacattttc atcccgaagc catagagaca tttgctgtca tattgctgct gggcacatct   2280

gtgctcttgg tgaggagagc aagaggaacc agaagaagtc tctttggtca gggaccatga   2340

tgctctacat ggacatttga gtcttcgtct tctgctgctg ctcggctgga ccagcttctt   2400

taacagcaag cataatccac ttcaatgtaa tattttctgt agctccaaag gctatctctt   2460

catattgact gcagacagac tgaatggaca gtttcttaga gggcttgtct cctttctacc   2520

cttgtcctct ttcctttcct ttgacctaat ggagctagaa atatgtctgt gactccacca   2580

gttattctaa taatttgttt tcttgaaaat tgttaatttc aagactggag aaataaactc   2640

accttctatt tactctgtga ctttatgaga ggttgaggga aaagtggaag ctgtacttgg   2700

gaattgtgga gaagaccgcc actccatctg atttgcataa atgactcagt gggcttttgt   2760

atctcttcat ttaagaatta tttgaatgcc tgccaggagc cagatttgtt ctgggtatta   2820

ggaatacact ggttaacagg accaaaaaag accctgccct cactgagttt taaattttag   2880

tggagagatg gaaaataatt aaacaaataa acaatgttat agattgtga               2929


<210>  9828
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  9828

Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His His 
1               5                   10                  15


Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu Ser 
            20                  25                  30


Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala Cys 
        35                  40                  45


Thr Ser Ala Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr 
    50                  55                  60


Asp Glu Asp Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe 
65                  70                  75                  80


Thr Thr Glu Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln His 
                85                  90                  95


Val Lys Arg Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln Asp 
            100                 105                 110


Gly Ile Asp Leu Lys Ser Ile Lys Trp Thr Gln His 
        115                 120


<210>  9829
<211>  2656
<212>  DNA
<213>  Homo sapiens

<400>  9829
acgctcgggt cccgctctcc gggaggcgcg gacctgtccc ctccgcgcgg cgacgcaact     60

gaatattccg gagccttcct gtccaccctg ctgcccagac cctctgaccc ttctctcaaa    120

tgacacatcc ctcaaacttt cttaggcggg tccccgaacg gttgaccccg gcgcaccacc    180

cctcgcaccc tgcgcgacag gcccccagag ccgtggaggc gcgtccttca gaccgctcct    240

ggccaagtta cagatgctgc tccgggctcc cgtgcagacc gttaccttcg gtcagaaggg    300

actgcaccta ctctggctcc acgttccttc taaacgtctt tgccctttag agccttcctt    360

cctacgatac catttgaata tcaactcaac accccctcca ggaaccctct ctccctctcc    420

cttacctcct tttacagcgt gtcagttgga gaccgtgctc ctcagtctgc ggttcccgca    480

gatacagccg ctgccccgga ggtggggcca gtgctgcgac ctctctatat ggatgtgcaa    540

gctacaactc ctctggaccc ccgggtgctt gatgccatgc tcccttacct aatcaactac    600

tatgggaacc cacactcccg gacacatgct tatggctggg agagtgaggc agccatggaa    660

cgtgctcgtc agcaagtagc atctctgatt ggagctgatc ctcgtgagat catttttact    720

agtggtgcta ctgaatccaa caacatagca attaaggggg tggcccgatt ctacaggtca    780

cggaaaaagc acttgatcac cacccagaca gaacacaaat gtgtcttgga ctcctgccgt    840

tcactggaag ctgagggctt tcaggtcacc tacctcccag tgcagaagag tgggatcatt    900

gacctaaagg aactagaggc tgctatccag ccagatacta gcctggtgtc agtcatgact    960

gtgaacaatg agattggagt gaagcagcct attgcagaaa tagggcggat ttgcagttcc   1020

agaaaggtat atttccatac tgatgcagcc caggctgttg gaaaaatccc acttgatgtc   1080

aatgacatga aaattgatct catgagcatt agtggtcaca aaatctacgg tcccaaaggg   1140

gttggtgcca tctacatccg tcgccggccc cgtgtgcgtg tggaggccct gcagagtgga   1200

ggggggcagg agcggggtat gcggtctggg acagtgccca cacccttagt ggtggggctg   1260

ggggctgcgt gtgaggtggc acagcaagag atggagtatg accacaagcg aatctcaaag   1320

ttgtcagagc ggctgataca gaatataatg aagagccttc cagatgtggt gatgaatggg   1380

gaccctaagc accattatcc cggctgtatc aacctctcct ttgcatatgt ggaaggggaa   1440

agtctgctga tggcactgaa ggacgttgcc ttatcctcag ggagtgcctg cacctctgca   1500

tccctggagc cctcttatgt gcttagagca attggcactg atgaggattt agcgcactct   1560

tctatcaggt ttggaattgg ccgcttcact acagaggagg aagtggacta cacagtggag   1620

aaatgcattc agcatgtgaa gcgtcttcga gaaatgagcc ctctctggga gatggttcag   1680

gatggcattg acctcaagag catcaagtgg acccaacact agaagaatag ggccctgact   1740

ttgtgctggt ctggcccctc ctgcctcacc aacccgtgca caaccagaca ccttgttaca   1800

cctagtggat gctctagatt ggtatagacc agttgacttc agcatcagtc cacctctatg   1860

acagaaacac aagaaaactg tctttcccta gcttcagttc cttgggtgtg gagcactccc   1920

catttcttct cgggtcttaa agtgtgtgga cattttcatc ccgaagccat agagacattt   1980

gctgtcatat tgctgctggg cacatctgtg ctcttggtga ggagagcaag aggaaccaga   2040

agaagtctct ttggtcaggg accatgatgc tctacatgga catttgagtc ttcgtcttct   2100

gctgctgctc ggctggacca gcttctttaa cagcaagcat aatccacttc aatgtaatat   2160

tttctgtagc tccaaaggct atctcttcat attgactgca gacagactga atggacagtt   2220

tcttagaggg cttgtctcct ttctaccctt gtcctctttc ctttcctttg acctaatgga   2280

gctagaaata tgtctgtgac tccaccagtt attctaataa tttgttttct tgaaaattgt   2340

taatttcaag actggagaaa taaactcacc ttctatttac tctgtgactt tatgagaggt   2400

tgagggaaaa gtggaagctg tacttgggaa ttgtggagaa gaccgccact ccatctgatt   2460

tgcataaatg actcagtggg cttttgtatc tcttcattta agaattattt gaatgcctgc   2520

caggagccag atttgttctg ggtattagga atacactggt taacaggacc aaaaaagacc   2580

ctgccctcac tgagttttaa attttagtgg agagatggaa aataattaaa caaataaaca   2640

atgttataga ttgtga                                                   2656


<210>  9830
<211>  397
<212>  PRT
<213>  Homo sapiens

<400>  9830

Met Asp Val Gln Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala 
1               5                   10                  15


Met Leu Pro Tyr Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr 
            20                  25                  30


His Ala Tyr Gly Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln 
        35                  40                  45


Gln Val Ala Ser Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr 
    50                  55                  60


Ser Gly Ala Thr Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg 
65                  70                  75                  80


Phe Tyr Arg Ser Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His 
                85                  90                  95


Lys Cys Val Leu Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln 
            100                 105                 110


Val Thr Tyr Leu Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu 
        115                 120                 125


Leu Glu Ala Ala Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr 
    130                 135                 140


Val Asn Asn Glu Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg 
145                 150                 155                 160


Ile Cys Ser Ser Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala 
                165                 170                 175


Val Gly Lys Ile Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met 
            180                 185                 190


Ser Ile Ser Gly His Lys Ile Tyr Gly Pro Lys Gly Val Gly Ala Ile 
        195                 200                 205


Tyr Ile Arg Arg Arg Pro Arg Val Arg Val Glu Ala Leu Gln Ser Gly 
    210                 215                 220


Gly Gly Gln Glu Arg Gly Met Arg Ser Gly Thr Val Pro Thr Pro Leu 
225                 230                 235                 240


Val Val Gly Leu Gly Ala Ala Cys Glu Val Ala Gln Gln Glu Met Glu 
                245                 250                 255


Tyr Asp His Lys Arg Ile Ser Lys Leu Ser Glu Arg Leu Ile Gln Asn 
            260                 265                 270


Ile Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His 
        275                 280                 285


His Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu 
    290                 295                 300


Ser Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala 
305                 310                 315                 320


Cys Thr Ser Ala Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly 
                325                 330                 335


Thr Asp Glu Asp Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg 
            340                 345                 350


Phe Thr Thr Glu Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln 
        355                 360                 365


His Val Lys Arg Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln 
    370                 375                 380


Asp Gly Ile Asp Leu Lys Ser Ile Lys Trp Thr Gln His 
385                 390                 395


<210>  9831
<211>  2096
<212>  DNA
<213>  Homo sapiens

<400>  9831
acttccggga gcctggggcc caggactgca gcggcttcgg aagttggaga ccgtgctcct     60

cagtctgcgg ttcccgcaga tacagccgct gccccggagg tggggccagt gctgcgacct    120

ctctatatgg atgtgcaagc tacaactcct ctggaccccc gggtgcttga tgccatgctc    180

ccttacctaa tcaactacta tgggaaccca cactcccgga cacatgctta tggctgggag    240

agtgaggcag ccatggaacg tgctcgtcag caagtagcat ctctgattgg agctgatcct    300

cgtgagatca tttttactag tggtgctact gaatccaaca acatagcaat taagggggtg    360

gcccgattct acaggtcacg gaaaaagcac ttgatcacca cccagacaga acacaaatgt    420

gtcttggact cctgccgttc actggaagct gagggctttc aggtcaccta cctcccagtg    480

cagaagagtg ggatcattga cctaaaggaa ctagaggctg ctatccagcc agatactagc    540

ctggtgtcag tcatgactgt gaacaatgag attggagtga agcagcctat tgcagaaata    600

gggcggattt gcagttccag aaaggtatat ttccatactg atgcagccca ggctgttgga    660

aaaatcccac ttgatgtcaa tgacatgaaa attgatctca tgagcattag tggtcacaaa    720

atctacggtc ccaaagtatg accacaagcg aatctcaaag ttgtcagagc ggctgataca    780

gaatataatg aagagccttc cagatgtggt gatgaatggg gaccctaagc accattatcc    840

cggctgtatc aacctctcct ttgcatatgt ggaaggggaa agtctgctga tggcactgaa    900

ggacgttgcc ttatcctcag ggagtgcctg cacctctgca tccctggagc cctcttatgt    960

gcttagagca attggcactg atgaggattt agcgcactct tctatcaggt ttggaattgg   1020

ccgcttcact acagaggagg aagtggacta cacagtggag aaatgcattc agcatgtgaa   1080

gcgtcttcga gaaatgagcc ctctctggga gatggttcag gatggcattg acctcaagag   1140

catcaagtgg acccaacact agaagaatag ggccctgact ttgtgctggt ctggcccctc   1200

ctgcctcacc aacccgtgca caaccagaca ccttgttaca cctagtggat gctctagatt   1260

ggtatagacc agttgacttc agcatcagtc cacctctatg acagaaacac aagaaaactg   1320

tctttcccta gcttcagttc cttgggtgtg gagcactccc catttcttct cgggtcttaa   1380

agtgtgtgga cattttcatc ccgaagccat agagacattt gctgtcatat tgctgctggg   1440

cacatctgtg ctcttggtga ggagagcaag aggaaccaga agaagtctct ttggtcaggg   1500

accatgatgc tctacatgga catttgagtc ttcgtcttct gctgctgctc ggctggacca   1560

gcttctttaa cagcaagcat aatccacttc aatgtaatat tttctgtagc tccaaaggct   1620

atctcttcat attgactgca gacagactga atggacagtt tcttagaggg cttgtctcct   1680

ttctaccctt gtcctctttc ctttcctttg acctaatgga gctagaaata tgtctgtgac   1740

tccaccagtt attctaataa tttgttttct tgaaaattgt taatttcaag actggagaaa   1800

taaactcacc ttctatttac tctgtgactt tatgagaggt tgagggaaaa gtggaagctg   1860

tacttgggaa ttgtggagaa gaccgccact ccatctgatt tgcataaatg actcagtggg   1920

cttttgtatc tcttcattta agaattattt gaatgcctgc caggagccag atttgttctg   1980

ggtattagga atacactggt taacaggacc aaaaaagacc ctgccctcac tgagttttaa   2040

attttagtgg agagatggaa aataattaaa caaataaaca atgttataga ttgtga       2096


<210>  9832
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  9832

Met Asp Val Gln Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala 
1               5                   10                  15


Met Leu Pro Tyr Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr 
            20                  25                  30


His Ala Tyr Gly Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln 
        35                  40                  45


Gln Val Ala Ser Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr 
    50                  55                  60


Ser Gly Ala Thr Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg 
65                  70                  75                  80


Phe Tyr Arg Ser Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His 
                85                  90                  95


Lys Cys Val Leu Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln 
            100                 105                 110


Val Thr Tyr Leu Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu 
        115                 120                 125


Leu Glu Ala Ala Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr 
    130                 135                 140


Val Asn Asn Glu Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg 
145                 150                 155                 160


Ile Cys Ser Ser Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala 
                165                 170                 175


Val Gly Lys Ile Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met 
            180                 185                 190


Ser Ile Ser Gly His Lys Ile Tyr Gly Pro Lys Val 
        195                 200


<210>  9833
<211>  2254
<212>  DNA
<213>  Homo sapiens

<400>  9833
acttccggga gcctggggcc caggactgca gcggcttcgg aagttggaga ccgtgctcct     60

cagtctgcgg ttcccgcaga tacagccgct gccccggagg tggggccagt gctgcgacct    120

ctctatatgg atgtgcaagc tacaactcct ctggaccccc gggtgcttga tgccatgctc    180

ccttacctaa tcaactacta tgggaaccca cactcccgga cacatgctta tggctgggag    240

agtgaggcag ccatggaacg tgctcgtcag caagtagcat ctctgattgg agctgatcct    300

cgtgagatca tttttactag tggtgctact gaatccaaca acatagcaat taagggggtg    360

gcccgattct acaggtcacg gaaaaagcac ttgatcacca cccagacaga acacaaatgt    420

gtcttggact cctgccgttc actggaagct gagggctttc aggtcaccta cctcccagtg    480

cagaagagtg ggatcattga cctaaaggaa ctagaggctg ctatccagcc agatactagc    540

ctggtgtcag tcatgactgt gaacaatgag attggagtga agcagcctat tgcagaaata    600

gggcggattt gcagttccag aaaggtatat ttccatactg atgcagccca ggctgttgga    660

aaaatcccac ttgatgtcaa tgacatgaaa attgatctca tgagcattag tggtcacaaa    720

atctacggtc ccaaaggggt tggtgccatc tacatccgtc gccggccccg tgtgcgtgtg    780

gaggccctgc agagtggagg ggggcaggag cggggtatgc ggtctgggac agtgcccaca    840

cccttagtgg tggggctggg ggctgcgtgt gaggtggcac agcaagagat ggagtatgac    900

cacaagcgaa tctcaaagtt gtcagagcgg ctgatacaga atataatgaa gagccttcca    960

gatgtggtga tgaatgggga ccctaagcac cattatcccg gctgtatcaa cctctccttt   1020

gcatatgtgg aaggggaaag tctgctgatg gcactgaagg acgttgcctt atcctcaggg   1080

agtgcctgca cctctgcatc cctggagccc tcttatgtgc ttagagcaat tggcactgat   1140

gaggatttag cgcactcttc tatcaggttt ggaattggcc gcttcactac agaggaggaa   1200

gtggactaca cagtggagaa atgcattcag catgtgaagc gtcttcgaga aatgagccct   1260

ctctgggaga tggttcagga tggcattgac ctcaagagca tcaagtggac ccaacactag   1320

aagaataggg ccctgacttt gtgctggtct ggcccctcct gcctcaccaa cccgtgcaca   1380

accagacacc ttgttacacc tagtggatgc tctagattgg tatagaccag ttgacttcag   1440

catcagtcca cctctatgac agaaacacaa gaaaactgtc tttccctagc ttcagttcct   1500

tgggtgtgga gcactcccca tttcttctcg ggtcttaaag tgtgtggaca ttttcatccc   1560

gaagccatag agacatttgc tgtcatattg ctgctgggca catctgtgct cttggtgagg   1620

agagcaagag gaaccagaag aagtctcttt ggtcagggac catgatgctc tacatggaca   1680

tttgagtctt cgtcttctgc tgctgctcgg ctggaccagc ttctttaaca gcaagcataa   1740

tccacttcaa tgtaatattt tctgtagctc caaaggctat ctcttcatat tgactgcaga   1800

cagactgaat ggacagtttc ttagagggct tgtctccttt ctacccttgt cctctttcct   1860

ttcctttgac ctaatggagc tagaaatatg tctgtgactc caccagttat tctaataatt   1920

tgttttcttg aaaattgtta atttcaagac tggagaaata aactcacctt ctatttactc   1980

tgtgacttta tgagaggttg agggaaaagt ggaagctgta cttgggaatt gtggagaaga   2040

ccgccactcc atctgatttg cataaatgac tcagtgggct tttgtatctc ttcatttaag   2100

aattatttga atgcctgcca ggagccagat ttgttctggg tattaggaat acactggtta   2160

acaggaccaa aaaagaccct gccctcactg agttttaaat tttagtggag agatggaaaa   2220

taattaaaca aataaacaat gttatagatt gtga                               2254


<210>  9834
<211>  397
<212>  PRT
<213>  Homo sapiens

<400>  9834

Met Asp Val Gln Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala 
1               5                   10                  15


Met Leu Pro Tyr Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr 
            20                  25                  30


His Ala Tyr Gly Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln 
        35                  40                  45


Gln Val Ala Ser Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr 
    50                  55                  60


Ser Gly Ala Thr Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg 
65                  70                  75                  80


Phe Tyr Arg Ser Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His 
                85                  90                  95


Lys Cys Val Leu Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln 
            100                 105                 110


Val Thr Tyr Leu Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu 
        115                 120                 125


Leu Glu Ala Ala Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr 
    130                 135                 140


Val Asn Asn Glu Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg 
145                 150                 155                 160


Ile Cys Ser Ser Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala 
                165                 170                 175


Val Gly Lys Ile Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met 
            180                 185                 190


Ser Ile Ser Gly His Lys Ile Tyr Gly Pro Lys Gly Val Gly Ala Ile 
        195                 200                 205


Tyr Ile Arg Arg Arg Pro Arg Val Arg Val Glu Ala Leu Gln Ser Gly 
    210                 215                 220


Gly Gly Gln Glu Arg Gly Met Arg Ser Gly Thr Val Pro Thr Pro Leu 
225                 230                 235                 240


Val Val Gly Leu Gly Ala Ala Cys Glu Val Ala Gln Gln Glu Met Glu 
                245                 250                 255


Tyr Asp His Lys Arg Ile Ser Lys Leu Ser Glu Arg Leu Ile Gln Asn 
            260                 265                 270


Ile Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His 
        275                 280                 285


His Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu 
    290                 295                 300


Ser Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala 
305                 310                 315                 320


Cys Thr Ser Ala Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly 
                325                 330                 335


Thr Asp Glu Asp Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg 
            340                 345                 350


Phe Thr Thr Glu Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln 
        355                 360                 365


His Val Lys Arg Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln 
    370                 375                 380


Asp Gly Ile Asp Leu Lys Ser Ile Lys Trp Thr Gln His 
385                 390                 395


<210>  9835
<211>  2385
<212>  DNA
<213>  Homo sapiens

<400>  9835
agcgccgggc agcacttccg ggagcctggg gcccaggact gcagcggctt cggaaggtgg     60

gctctgccag cgggaccatg ctgctccgag ccgcttggag gcgggcggca gtggcggtga    120

cagcggctcc agggccgaag cccgcggcgc ccactcgggg gctgcgcctg cgcgttggag    180

accgtgctcc tcagtctgcg gttcccgcag atacagccgc tgccccggag gtggggccag    240

tgctgcgacc tctctatatg gatgtgcaag ctacaactcc tctggacccc cgggtgcttg    300

atgccatgct cccttaccta atcaactact atgggaaccc acactcccgg acacatgctt    360

atggctggga gagtgaggca gccatggaac gtgctcgtca gcaagtagca tctctgattg    420

gagctgatcc tcgtgagatc atttttacta gtggtgctac tgaatccaac aacatagcaa    480

ttaagggggt ggcccgattc tacaggtcac ggaaaaagca cttgatcacc acccagacag    540

aacacaaatg tgtcttggac tcctgccgtt cactggaagc tgagggcttt caggtcacct    600

acctcccagt gcagaagagt gggatcattg acctaaagga actagaggct gctatccagc    660

cagatactag cctggtgtca gtcatgactg tgaacaatga gattggagtg aagcagccta    720

ttgcagaaat agggcggatt tgcagttcca gaaaggtata tttccatact gatgcagccc    780

aggctgttgg aaaaatccca cttgatgtca atgacatgaa aattgatctc atgagcatta    840

gtggtcacaa aatctacggt cccaaagggg ttggtgccat ctacatccgt cgccggcccc    900

gtgtgcgtgt ggaggccctg cagagtggag gggggcagga gcggggtatg cggtctggga    960

cagtgcccac acccttagtg gtggggctgg gggctgcgtg tgaggtggca cagcaagaga   1020

tggagtatga ccacaagcga atctcaaagt tgtcagagcg gctgatacag aatataatga   1080

agagccttcc agatgtggtg atgaatgggg accctaagca ccattatccc ggctgtatca   1140

acctctcctt tgcatatgtg gaaggggaaa gtctgctgat ggcactgaag gacgttgcct   1200

tatcctcagg gagtgcctgc acctctgcat ccctggagcc ctcttatgtg cttagagcaa   1260

ttggcactga tgaggattta gcgcactctt ctatcaggtt tggaattggc cgcttcacta   1320

cagaggagga agtggactac acagtggaga aatgcattca gcatgtgaag cgtcttcgag   1380

aaatgagccc tctctgggag atggttcagg atggcattga cctcaagagc atcaagtgga   1440

cccaacacta gaagaatagg gccctgactt tgtgctggtc tggcccctcc tgcctcacca   1500

acccgtgcac aaccagacac cttgttacac ctagtggatg ctctagattg gtatagacca   1560

gttgacttca gcatcagtcc acctctatga cagaaacaca agaaaactgt ctttccctag   1620

cttcagttcc ttgggtgtgg agcactcccc atttcttctc gggtcttaaa gtgtgtggac   1680

attttcatcc cgaagccata gagacatttg ctgtcatatt gctgctgggc acatctgtgc   1740

tcttggtgag gagagcaaga ggaaccagaa gaagtctctt tggtcaggga ccatgatgct   1800

ctacatggac atttgagtct tcgtcttctg ctgctgctcg gctggaccag cttctttaac   1860

agcaagcata atccacttca atgtaatatt ttctgtagct ccaaaggcta tctcttcata   1920

ttgactgcag acagactgaa tggacagttt cttagagggc ttgtctcctt tctacccttg   1980

tcctctttcc tttcctttga cctaatggag ctagaaatat gtctgtgact ccaccagtta   2040

ttctaataat ttgttttctt gaaaattgtt aatttcaaga ctggagaaat aaactcacct   2100

tctatttact ctgtgacttt atgagaggtt gagggaaaag tggaagctgt acttgggaat   2160

tgtggagaag accgccactc catctgattt gcataaatga ctcagtgggc ttttgtatct   2220

cttcatttaa gaattatttg aatgcctgcc aggagccaga tttgttctgg gtattaggaa   2280

tacactggtt aacaggacca aaaaagaccc tgccctcact gagttttaaa ttttagtgga   2340

gagatggaaa ataattaaac aaataaacaa tgttatagat tgtga                   2385


<210>  9836
<211>  457
<212>  PRT
<213>  Homo sapiens

<400>  9836

Met Leu Leu Arg Ala Ala Trp Arg Arg Ala Ala Val Ala Val Thr Ala 
1               5                   10                  15


Ala Pro Gly Pro Lys Pro Ala Ala Pro Thr Arg Gly Leu Arg Leu Arg 
            20                  25                  30


Val Gly Asp Arg Ala Pro Gln Ser Ala Val Pro Ala Asp Thr Ala Ala 
        35                  40                  45


Ala Pro Glu Val Gly Pro Val Leu Arg Pro Leu Tyr Met Asp Val Gln 
    50                  55                  60


Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala Met Leu Pro Tyr 
65                  70                  75                  80


Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr His Ala Tyr Gly 
                85                  90                  95


Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln Gln Val Ala Ser 
            100                 105                 110


Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr Ser Gly Ala Thr 
        115                 120                 125


Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg Phe Tyr Arg Ser 
    130                 135                 140


Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His Lys Cys Val Leu 
145                 150                 155                 160


Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln Val Thr Tyr Leu 
                165                 170                 175


Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu Leu Glu Ala Ala 
            180                 185                 190


Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr Val Asn Asn Glu 
        195                 200                 205


Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg Ile Cys Ser Ser 
    210                 215                 220


Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala Val Gly Lys Ile 
225                 230                 235                 240


Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met Ser Ile Ser Gly 
                245                 250                 255


His Lys Ile Tyr Gly Pro Lys Gly Val Gly Ala Ile Tyr Ile Arg Arg 
            260                 265                 270


Arg Pro Arg Val Arg Val Glu Ala Leu Gln Ser Gly Gly Gly Gln Glu 
        275                 280                 285


Arg Gly Met Arg Ser Gly Thr Val Pro Thr Pro Leu Val Val Gly Leu 
    290                 295                 300


Gly Ala Ala Cys Glu Val Ala Gln Gln Glu Met Glu Tyr Asp His Lys 
305                 310                 315                 320


Arg Ile Ser Lys Leu Ser Glu Arg Leu Ile Gln Asn Ile Met Lys Ser 
                325                 330                 335


Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His His Tyr Pro Gly 
            340                 345                 350


Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu Ser Leu Leu Met 
        355                 360                 365


Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala Cys Thr Ser Ala 
    370                 375                 380


Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr Asp Glu Asp 
385                 390                 395                 400


Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe Thr Thr Glu 
                405                 410                 415


Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln His Val Lys Arg 
            420                 425                 430


Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln Asp Gly Ile Asp 
        435                 440                 445


Leu Lys Ser Ile Lys Trp Thr Gln His 
    450                 455


<210>  9837
<211>  977
<212>  DNA
<213>  Homo sapiens

<400>  9837
agaattgaag atgctccaaa ggccactaag tgtttggctg cccttcaggc tggtgcagat     60

ggtgcattac gtcctgggga atgcctgcac ctctgcatcc ctggagccct cttatgtgct    120

tagagcaatt ggcactgatg aggatttagc gcactcttct atcaggtttg gaattggccg    180

cttcactaca gaggaggaag tggactacac agtggagaaa tgcattcagc atgtgaagcg    240

tcttcgagaa atgagccctc tctgggagat ggttcaggat ggcattgacc tcaagagcat    300

caagtggacc caacactaga agaatagggc cctgactttg tgctggtctg gcccctcctg    360

cctcaccaac ccgtgcacaa ccagacacct tgttacacct agtggatgct ctagattggt    420

atagaccagt tgacttcagc atcagtccac ctctatgaca gaaacacaag aaaactgtct    480

ttccctagct tcagttcctt gggtgtggag cactccccat ttcttctcgg gtcttaaagt    540

gtgtggacat tttcatcccg aagccataga gacatttgct gtcatattgc tgctgggcac    600

atctgtgctc ttggtgagga gagcaagagg aaccagaaga agtctctttg gtcagggacc    660

atgatgctct acatggacat ttgagtcttc gtcttctgct gctgctcggc tggaccagct    720

tctttaacag caagcataat ccacttcaat gtaatatttt ctgtagctcc aaaggctatc    780

tcttcatatt gactgcagac agactgaatg gacagtttct tagagggctt gtctcctttc    840

tacccttgtc ctctttcctt tcctttgacc taatggagct agaaatatgt ctgtgactcc    900

accagttatt ctaataattt gttttcttga aaattgttaa tttcaagact ggagaaataa    960

actcaccttc tatttac                                                   977


<210>  9838
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  9838

Met Leu Gln Arg Pro Leu Ser Val Trp Leu Pro Phe Arg Leu Val Gln 
1               5                   10                  15


Met Val His Tyr Val Leu Gly Asn Ala Cys Thr Ser Ala Ser Leu Glu 
            20                  25                  30


Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr Asp Glu Asp Leu Ala His 
        35                  40                  45


Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe Thr Thr Glu Glu Glu Val 
    50                  55                  60


Asp Tyr Thr Val Glu Lys Cys Ile Gln His Val Lys Arg Leu Arg Glu 
65                  70                  75                  80


Met Ser Pro Leu Trp Glu Met Val Gln Asp Gly Ile Asp Leu Lys Ser 
                85                  90                  95


Ile Lys Trp Thr Gln His 
            100


<210>  9839
<211>  2653
<212>  DNA
<213>  Homo sapiens

<400>  9839
cagcctccct agtagctggg attacaggca tgtgccacca tgcctggcta attttgtatt     60

tttagtggag aaggggtttc tccatgttgg tcaggctggt ctcaaactcc cgaactcagg    120

tgatccaccc acctcagcct cccaaagtgc tggtattaca ggcgtgagcc actgcgcccg    180

gccaatacat ctttgttttt tcaagctaaa gtacagactt ttttttggat ttcaccagtt    240

ttgtaacaat gtatcttgga gattttatgg tgtcagttca gaacaagctt cttctttttt    300

tttttttttt ttttgggaga cagagtcttg ctccatcact caggctggag tgcagtggct    360

tgatctcagc tcactgcaac ctctaccacc tgggttcatc tcatgtctca gcctcctgag    420

tagctgggat tacatgtgcc tgctaccacg cttggctaat ctttgtattt ttagtagaga    480

gagggtttca ccatgttgac caggctggtt tctaacttct gatctcaggt gatccgcccg    540

ccttgacctc ccacagttgg gattataggc gtgaaccacc acacccggcc ccctcattct    600

tttatacacc tgcttggtat ttcattgtat ggacatgcca taatctattt gaccattacc    660

ctgatgatgg acatctaagt tgttcccagt atttttgcta ttatgaataa tactgtaatg    720

tatgatggca tttcatatag catagggagc tactttaaac cattttgatc attactcctt    780

ctggcattta tcttccagat gttaaatatt ttactaaata ctatgctttt actgctgttt    840

cttcttttcc ttaacgtttt ttatttagaa aaatttcatg cttacagaaa agttgaagta    900

atattttgat ccctttggaa agaaatattt tgttttatct acttttctct ctttctgttt    960

tttgtaacaa attttgtttc ccaggggttg gtgccatcta catccgtcgc cggccccgtg   1020

tgcgtgtgga ggccctgcag agtggagggg ggcaggagcg gggtatgcgg tctgggacag   1080

tgcccacacc cttagtggtg gggctggggg ctgcgtgtga ggtggcacag caagagatgg   1140

aggtatgggg agagcagttc cctcccacaa cttcttcccc tgtgctgggt ctcctattta   1200

gaggcttctc agcatgactg aggcagatct ctgcagggag agagggctta agaaaactct   1260

tccttgtcct ggtgctgctg gcaccttgtt ctgagggaga cattatgggc ttcaaaaccc   1320

atggcctttt agtagttatc agctcattta tttctggata agtaaatgaa ccctgtgtcc   1380

agttatcaag cgccttttgc ataccaggca ctatgctcag tactggagat acagtggtcc   1440

ccatgagtac ataggatgat aggtggggct gatacatagt cacttccagt tataggagaa   1500

gggcttctca aactgtcttt ctgagctggt taatggttac tgcctaatcc ttccttgcct   1560

gctccttagt atgaccacaa gcgaatctca aagttgtcag agcggctgat acagaatata   1620

atgaagagcc ttccagatgt ggtgatgaat ggggacccta agcaccatta tcccggctgt   1680

atcaacctct cctttgcata tgtggaaggg gaaagtctgc tgatggcact gaaggacgtt   1740

gccttatcct cagggagtgc ctgcacctct gcatccctgg agccctctta tgtgcttaga   1800

gcaattggca ctgatgagga tttagcgcac tcttctatca ggtttggaat tggccgcttc   1860

actacagagg aggaagtgga ctacacagtg gagaaatgca ttcagcatgt gaagcgtctt   1920

cgagaaatga gccctctctg ggagatggtt caggatggca ttgacctcaa gagcatcaag   1980

tggacccaac actagaagaa tagggccctg actttgtgct ggtctggccc ctcctgcctc   2040

accaacccgt gcacaaccag acaccttgtt acacctagtg gatgctctag attggtatag   2100

accagttgac ttcagcatca gtccacctct atgacagaaa cacaagaaaa ctgtctttcc   2160

ctagcttcag ttccttgggt gtggagcact ccccatttct tctcgggtct taaagtgtgt   2220

ggacattttc atcccgaagc catagagaca tttgctgtca tattgctgct gggcacatct   2280

gtgctcttgg tgaggagagc aagaggaacc agaagaagtc tctttggtca gggaccatga   2340

tgctctacat ggacatttga gtcttcgtct tctgctgctg ctcggctgga ccagcttctt   2400

taacagcaag cataatccac ttcaatgtaa tattttctgt agctccaaag gctatctctt   2460

catattgact gcagacagac tgaatggaca gtttcttaga gggcttgtct cctttctacc   2520

cttgtcctct ttcctttcct ttgacctaat ggagctagaa atatgtctgt gactccacca   2580

gttattctaa taatttgttt tcttgaaaat tgttaatttc aagactggag aaataaactc   2640

accttctatt tac                                                      2653


<210>  9840
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  9840

Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His His 
1               5                   10                  15


Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu Ser 
            20                  25                  30


Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala Cys 
        35                  40                  45


Thr Ser Ala Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr 
    50                  55                  60


Asp Glu Asp Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe 
65                  70                  75                  80


Thr Thr Glu Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln His 
                85                  90                  95


Val Lys Arg Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln Asp 
            100                 105                 110


Gly Ile Asp Leu Lys Ser Ile Lys Trp Thr Gln His 
        115                 120


<210>  9841
<211>  1978
<212>  DNA
<213>  Homo sapiens

<400>  9841
acttccggga gcctggggcc caggactgca gcggcttcgg aagttggaga ccgtgctcct     60

cagtctgcgg ttcccgcaga tacagccgct gccccggagg tggggccagt gctgcgacct    120

ctctatatgg atgtgcaagc tacaactcct ctggaccccc gggtgcttga tgccatgctc    180

ccttacctaa tcaactacta tgggaaccca cactcccgga cacatgctta tggctgggag    240

agtgaggcag ccatggaacg tgctcgtcag caagtagcat ctctgattgg agctgatcct    300

cgtgagatca tttttactag tggtgctact gaatccaaca acatagcaat taagggggtg    360

gcccgattct acaggtcacg gaaaaagcac ttgatcacca cccagacaga acacaaatgt    420

gtcttggact cctgccgttc actggaagct gagggctttc aggtcaccta cctcccagtg    480

cagaagagtg ggatcattga cctaaaggaa ctagaggctg ctatccagcc agatactagc    540

ctggtgtcag tcatgactgt gaacaatgag attggagtga agcagcctat tgcagaaata    600

gggcggattt gcagttccag aaaggtatat ttccatactg atgcagccca ggctgttgga    660

aaaatcccac ttgatgtcaa tgacatgaaa attgatctca tgagcattag tggtcacaaa    720

atctacggtc ccaaaggggt tggtgccatc tacatccgtc gccggccccg tgtgcgtgtg    780

gaggccctgc agagtggagg ggggcaggag cggggtatgc ggtctgggac agtgcccaca    840

cccttagtgg tggggctggg ggctgcgtgt gaggtggcac agcaagagat ggagtatgac    900

cacaagcgaa tctcaaagtt gtcagagcgg ctgatacaga atataatgaa gagccttcca    960

gatgtggtga tgaatgggga ccctaagcac cattatcccg gctgtatcaa cctctccttt   1020

gcatatgtgg aaggggaaag tctgctgatg gcactgaagg acgttgcctt atcctcaggg   1080

agtgcctgca cctctgcatc cctggagccc tcttatgtgc ttagagcaat tggcactgat   1140

gaggatttag cgcactcttc tatcaggttt ggaattggcc gcttcactac agaggaggaa   1200

gtggactaca cagtggagaa atgcattcag catgtgaagc gtcttcgaga aatgagccct   1260

ctctgggaga tggttcagga tggcattgac ctcaagagca tcaagtggac ccaacactag   1320

aagaataggg ccctgacttt gtgctggtct ggcccctcct gcctcaccaa cccgtgcaca   1380

accagacacc ttgttacacc tagtggatgc tctagattgg tatagaccag ttgacttcag   1440

catcagtcca cctctatgac agaaacacaa gaaaactgtc tttccctagc ttcagttcct   1500

tgggtgtgga gcactcccca tttcttctcg ggtcttaaag tgtgtggaca ttttcatccc   1560

gaagccatag agacatttgc tgtcatattg ctgctgggca catctgtgct cttggtgagg   1620

agagcaagag gaaccagaag aagtctcttt ggtcagggac catgatgctc tacatggaca   1680

tttgagtctt cgtcttctgc tgctgctcgg ctggaccagc ttctttaaca gcaagcataa   1740

tccacttcaa tgtaatattt tctgtagctc caaaggctat ctcttcatat tgactgcaga   1800

cagactgaat ggacagtttc ttagagggct tgtctccttt ctacccttgt cctctttcct   1860

ttcctttgac ctaatggagc tagaaatatg tctgtgactc caccagttat tctaataatt   1920

tgttttcttg aaaattgtta atttcaagac tggagaaata aactcacctt ctatttac     1978


<210>  9842
<211>  397
<212>  PRT
<213>  Homo sapiens

<400>  9842

Met Asp Val Gln Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala 
1               5                   10                  15


Met Leu Pro Tyr Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr 
            20                  25                  30


His Ala Tyr Gly Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln 
        35                  40                  45


Gln Val Ala Ser Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr 
    50                  55                  60


Ser Gly Ala Thr Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg 
65                  70                  75                  80


Phe Tyr Arg Ser Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His 
                85                  90                  95


Lys Cys Val Leu Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln 
            100                 105                 110


Val Thr Tyr Leu Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu 
        115                 120                 125


Leu Glu Ala Ala Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr 
    130                 135                 140


Val Asn Asn Glu Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg 
145                 150                 155                 160


Ile Cys Ser Ser Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala 
                165                 170                 175


Val Gly Lys Ile Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met 
            180                 185                 190


Ser Ile Ser Gly His Lys Ile Tyr Gly Pro Lys Gly Val Gly Ala Ile 
        195                 200                 205


Tyr Ile Arg Arg Arg Pro Arg Val Arg Val Glu Ala Leu Gln Ser Gly 
    210                 215                 220


Gly Gly Gln Glu Arg Gly Met Arg Ser Gly Thr Val Pro Thr Pro Leu 
225                 230                 235                 240


Val Val Gly Leu Gly Ala Ala Cys Glu Val Ala Gln Gln Glu Met Glu 
                245                 250                 255


Tyr Asp His Lys Arg Ile Ser Lys Leu Ser Glu Arg Leu Ile Gln Asn 
            260                 265                 270


Ile Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His 
        275                 280                 285


His Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu 
    290                 295                 300


Ser Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala 
305                 310                 315                 320


Cys Thr Ser Ala Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly 
                325                 330                 335


Thr Asp Glu Asp Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg 
            340                 345                 350


Phe Thr Thr Glu Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln 
        355                 360                 365


His Val Lys Arg Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln 
    370                 375                 380


Asp Gly Ile Asp Leu Lys Ser Ile Lys Trp Thr Gln His 
385                 390                 395


<210>  9843
<211>  1820
<212>  DNA
<213>  Homo sapiens

<400>  9843
acttccggga gcctggggcc caggactgca gcggcttcgg aagttggaga ccgtgctcct     60

cagtctgcgg ttcccgcaga tacagccgct gccccggagg tggggccagt gctgcgacct    120

ctctatatgg atgtgcaagc tacaactcct ctggaccccc gggtgcttga tgccatgctc    180

ccttacctaa tcaactacta tgggaaccca cactcccgga cacatgctta tggctgggag    240

agtgaggcag ccatggaacg tgctcgtcag caagtagcat ctctgattgg agctgatcct    300

cgtgagatca tttttactag tggtgctact gaatccaaca acatagcaat taagggggtg    360

gcccgattct acaggtcacg gaaaaagcac ttgatcacca cccagacaga acacaaatgt    420

gtcttggact cctgccgttc actggaagct gagggctttc aggtcaccta cctcccagtg    480

cagaagagtg ggatcattga cctaaaggaa ctagaggctg ctatccagcc agatactagc    540

ctggtgtcag tcatgactgt gaacaatgag attggagtga agcagcctat tgcagaaata    600

gggcggattt gcagttccag aaaggtatat ttccatactg atgcagccca ggctgttgga    660

aaaatcccac ttgatgtcaa tgacatgaaa attgatctca tgagcattag tggtcacaaa    720

atctacggtc ccaaagtatg accacaagcg aatctcaaag ttgtcagagc ggctgataca    780

gaatataatg aagagccttc cagatgtggt gatgaatggg gaccctaagc accattatcc    840

cggctgtatc aacctctcct ttgcatatgt ggaaggggaa agtctgctga tggcactgaa    900

ggacgttgcc ttatcctcag ggagtgcctg cacctctgca tccctggagc cctcttatgt    960

gcttagagca attggcactg atgaggattt agcgcactct tctatcaggt ttggaattgg   1020

ccgcttcact acagaggagg aagtggacta cacagtggag aaatgcattc agcatgtgaa   1080

gcgtcttcga gaaatgagcc ctctctggga gatggttcag gatggcattg acctcaagag   1140

catcaagtgg acccaacact agaagaatag ggccctgact ttgtgctggt ctggcccctc   1200

ctgcctcacc aacccgtgca caaccagaca ccttgttaca cctagtggat gctctagatt   1260

ggtatagacc agttgacttc agcatcagtc cacctctatg acagaaacac aagaaaactg   1320

tctttcccta gcttcagttc cttgggtgtg gagcactccc catttcttct cgggtcttaa   1380

agtgtgtgga cattttcatc ccgaagccat agagacattt gctgtcatat tgctgctggg   1440

cacatctgtg ctcttggtga ggagagcaag aggaaccaga agaagtctct ttggtcaggg   1500

accatgatgc tctacatgga catttgagtc ttcgtcttct gctgctgctc ggctggacca   1560

gcttctttaa cagcaagcat aatccacttc aatgtaatat tttctgtagc tccaaaggct   1620

atctcttcat attgactgca gacagactga atggacagtt tcttagaggg cttgtctcct   1680

ttctaccctt gtcctctttc ctttcctttg acctaatgga gctagaaata tgtctgtgac   1740

tccaccagtt attctaataa tttgttttct tgaaaattgt taatttcaag actggagaaa   1800

taaactcacc ttctatttac                                               1820


<210>  9844
<211>  204
<212>  PRT
<213>  Homo sapiens

<400>  9844

Met Asp Val Gln Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala 
1               5                   10                  15


Met Leu Pro Tyr Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr 
            20                  25                  30


His Ala Tyr Gly Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln 
        35                  40                  45


Gln Val Ala Ser Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr 
    50                  55                  60


Ser Gly Ala Thr Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg 
65                  70                  75                  80


Phe Tyr Arg Ser Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His 
                85                  90                  95


Lys Cys Val Leu Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln 
            100                 105                 110


Val Thr Tyr Leu Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu 
        115                 120                 125


Leu Glu Ala Ala Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr 
    130                 135                 140


Val Asn Asn Glu Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg 
145                 150                 155                 160


Ile Cys Ser Ser Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala 
                165                 170                 175


Val Gly Lys Ile Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met 
            180                 185                 190


Ser Ile Ser Gly His Lys Ile Tyr Gly Pro Lys Val 
        195                 200


<210>  9845
<211>  2109
<212>  DNA
<213>  Homo sapiens

<400>  9845
agcgccgggc agcacttccg ggagcctggg gcccaggact gcagcggctt cggaaggtgg     60

gctctgccag cgggaccatg ctgctccgag ccgcttggag gcgggcggca gtggcggtga    120

cagcggctcc agggccgaag cccgcggcgc ccactcgggg gctgcgcctg cgcgttggag    180

accgtgctcc tcagtctgcg gttcccgcag atacagccgc tgccccggag gtggggccag    240

tgctgcgacc tctctatatg gatgtgcaag ctacaactcc tctggacccc cgggtgcttg    300

atgccatgct cccttaccta atcaactact atgggaaccc acactcccgg acacatgctt    360

atggctggga gagtgaggca gccatggaac gtgctcgtca gcaagtagca tctctgattg    420

gagctgatcc tcgtgagatc atttttacta gtggtgctac tgaatccaac aacatagcaa    480

ttaagggggt ggcccgattc tacaggtcac ggaaaaagca cttgatcacc acccagacag    540

aacacaaatg tgtcttggac tcctgccgtt cactggaagc tgagggcttt caggtcacct    600

acctcccagt gcagaagagt gggatcattg acctaaagga actagaggct gctatccagc    660

cagatactag cctggtgtca gtcatgactg tgaacaatga gattggagtg aagcagccta    720

ttgcagaaat agggcggatt tgcagttcca gaaaggtata tttccatact gatgcagccc    780

aggctgttgg aaaaatccca cttgatgtca atgacatgaa aattgatctc atgagcatta    840

gtggtcacaa aatctacggt cccaaagggg ttggtgccat ctacatccgt cgccggcccc    900

gtgtgcgtgt ggaggccctg cagagtggag gggggcagga gcggggtatg cggtctggga    960

cagtgcccac acccttagtg gtggggctgg gggctgcgtg tgaggtggca cagcaagaga   1020

tggagtatga ccacaagcga atctcaaagt tgtcagagcg gctgatacag aatataatga   1080

agagccttcc agatgtggtg atgaatgggg accctaagca ccattatccc ggctgtatca   1140

acctctcctt tgcatatgtg gaaggggaaa gtctgctgat ggcactgaag gacgttgcct   1200

tatcctcagg gagtgcctgc acctctgcat ccctggagcc ctcttatgtg cttagagcaa   1260

ttggcactga tgaggattta gcgcactctt ctatcaggtt tggaattggc cgcttcacta   1320

cagaggagga agtggactac acagtggaga aatgcattca gcatgtgaag cgtcttcgag   1380

aaatgagccc tctctgggag atggttcagg atggcattga cctcaagagc atcaagtgga   1440

cccaacacta gaagaatagg gccctgactt tgtgctggtc tggcccctcc tgcctcacca   1500

acccgtgcac aaccagacac cttgttacac ctagtggatg ctctagattg gtatagacca   1560

gttgacttca gcatcagtcc acctctatga cagaaacaca agaaaactgt ctttccctag   1620

cttcagttcc ttgggtgtgg agcactcccc atttcttctc gggtcttaaa gtgtgtggac   1680

attttcatcc cgaagccata gagacatttg ctgtcatatt gctgctgggc acatctgtgc   1740

tcttggtgag gagagcaaga ggaaccagaa gaagtctctt tggtcaggga ccatgatgct   1800

ctacatggac atttgagtct tcgtcttctg ctgctgctcg gctggaccag cttctttaac   1860

agcaagcata atccacttca atgtaatatt ttctgtagct ccaaaggcta tctcttcata   1920

ttgactgcag acagactgaa tggacagttt cttagagggc ttgtctcctt tctacccttg   1980

tcctctttcc tttcctttga cctaatggag ctagaaatat gtctgtgact ccaccagtta   2040

ttctaataat ttgttttctt gaaaattgtt aatttcaaga ctggagaaat aaactcacct   2100

tctatttac                                                           2109


<210>  9846
<211>  457
<212>  PRT
<213>  Homo sapiens

<400>  9846

Met Leu Leu Arg Ala Ala Trp Arg Arg Ala Ala Val Ala Val Thr Ala 
1               5                   10                  15


Ala Pro Gly Pro Lys Pro Ala Ala Pro Thr Arg Gly Leu Arg Leu Arg 
            20                  25                  30


Val Gly Asp Arg Ala Pro Gln Ser Ala Val Pro Ala Asp Thr Ala Ala 
        35                  40                  45


Ala Pro Glu Val Gly Pro Val Leu Arg Pro Leu Tyr Met Asp Val Gln 
    50                  55                  60


Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala Met Leu Pro Tyr 
65                  70                  75                  80


Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr His Ala Tyr Gly 
                85                  90                  95


Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln Gln Val Ala Ser 
            100                 105                 110


Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr Ser Gly Ala Thr 
        115                 120                 125


Glu Ser Asn Asn Ile Ala Ile Lys Gly Val Ala Arg Phe Tyr Arg Ser 
    130                 135                 140


Arg Lys Lys His Leu Ile Thr Thr Gln Thr Glu His Lys Cys Val Leu 
145                 150                 155                 160


Asp Ser Cys Arg Ser Leu Glu Ala Glu Gly Phe Gln Val Thr Tyr Leu 
                165                 170                 175


Pro Val Gln Lys Ser Gly Ile Ile Asp Leu Lys Glu Leu Glu Ala Ala 
            180                 185                 190


Ile Gln Pro Asp Thr Ser Leu Val Ser Val Met Thr Val Asn Asn Glu 
        195                 200                 205


Ile Gly Val Lys Gln Pro Ile Ala Glu Ile Gly Arg Ile Cys Ser Ser 
    210                 215                 220


Arg Lys Val Tyr Phe His Thr Asp Ala Ala Gln Ala Val Gly Lys Ile 
225                 230                 235                 240


Pro Leu Asp Val Asn Asp Met Lys Ile Asp Leu Met Ser Ile Ser Gly 
                245                 250                 255


His Lys Ile Tyr Gly Pro Lys Gly Val Gly Ala Ile Tyr Ile Arg Arg 
            260                 265                 270


Arg Pro Arg Val Arg Val Glu Ala Leu Gln Ser Gly Gly Gly Gln Glu 
        275                 280                 285


Arg Gly Met Arg Ser Gly Thr Val Pro Thr Pro Leu Val Val Gly Leu 
    290                 295                 300


Gly Ala Ala Cys Glu Val Ala Gln Gln Glu Met Glu Tyr Asp His Lys 
305                 310                 315                 320


Arg Ile Ser Lys Leu Ser Glu Arg Leu Ile Gln Asn Ile Met Lys Ser 
                325                 330                 335


Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His His Tyr Pro Gly 
            340                 345                 350


Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu Ser Leu Leu Met 
        355                 360                 365


Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Ser Ala Cys Thr Ser Ala 
    370                 375                 380


Ser Leu Glu Pro Ser Tyr Val Leu Arg Ala Ile Gly Thr Asp Glu Asp 
385                 390                 395                 400


Leu Ala His Ser Ser Ile Arg Phe Gly Ile Gly Arg Phe Thr Thr Glu 
                405                 410                 415


Glu Glu Val Asp Tyr Thr Val Glu Lys Cys Ile Gln His Val Lys Arg 
            420                 425                 430


Leu Arg Glu Met Ser Pro Leu Trp Glu Met Val Gln Asp Gly Ile Asp 
        435                 440                 445


Leu Lys Ser Ile Lys Trp Thr Gln His 
    450                 455


<210>  9847
<211>  1461
<212>  DNA
<213>  Homo sapiens

<400>  9847
aaagttgaag taatattttg atccctttgg aaagaaatat tttgttttat ctacttttct     60

ctctttctgt tttttgtaac aaattttgtt tcccaggggt tggtgccatc tacatccgtc    120

gccggccccg tgtgcgtgtg gaggccctgc agagtggagg ggggcaggag cggggtatgc    180

ggtctgggac agtgcccaca cccttagtgg tggggctggg ggctgcgtgt gaggtggcac    240

agcaagagat ggaggtatgg ggagagcagt tccctcccac aacttcttcc cctgtgctgg    300

gtctcctatt tagaggcttc tcagcatgac tgaggcagat ctctgcaggg agagagggct    360

taagaaaact cttccttgtc ctggtgctgc tggcaccttg ttctgaggga gacattatgg    420

gcttcaaaac ccatggcctt ttagtagtta tcagctcatt tatttctgga taagtaaatg    480

aaccctgtgt ccagttatca agcgcctttt gcataccagg cactatgctc agtactggag    540

atacagtggt ccccatgagt acataggatg ataggtgggg ctgatacata gtcacttcca    600

gttataggag aagggcttct caaactgtct ttctgagctg gttaatggtt actgcctaat    660

ccttccttgc ctgctcctta gtatgaccac aagcgaatct caaagttgtc agagcggctg    720

atacagaata taatgaagag ccttccagat gtggtgatga atggggaccc taagcaccat    780

tatcccggct gtatcaacct ctcctttgca tatgtggaag gggaaagtct gctgatggca    840

ctgaaggacg ttgccttatc ctcagggagg tgagctggac ggcatagaca gggcctgcgg    900

cagggccact tagaagagtc atacaggcta ttaaacttcc cagtgtggag atgataggca    960

caagacctct tgattaaggg taaaggtcat tttgtaagtg cctctctttt tttggttggc   1020

tgggtagctg ggtacagact gaagtttacc accctaggaa gacttcctgg ggtagaattt   1080

tgtgcctttt atcgtcccag gggatgtatg tgtctgttgt gggttacact agcagttctg   1140

ttacaggcct ctagaattga agatgctcca aaggccacta agtgtttggc tgcccttcag   1200

gctggtgcag atggtgcatt acgtcctggg gaagtgagca catggtcctc tgctgcgtct   1260

tcttgtcaaa cccatgtggt atcatgctct gtcacacttt gccagcgtcc ttgcttaagg   1320

aagtcatcca ccatgggggc cagaggagct aggttcacac atcctaggat gtgcagggga   1380

gcatcaggtc ctttagttct gccagattag aaggtctctt gttttctcca gggtatgact   1440

ccagggccct gggggatggg a                                             1461


<210>  9848
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  9848

Met Lys Ser Leu Pro Asp Val Val Met Asn Gly Asp Pro Lys His His 
1               5                   10                  15


Tyr Pro Gly Cys Ile Asn Leu Ser Phe Ala Tyr Val Glu Gly Glu Ser 
            20                  25                  30


Leu Leu Met Ala Leu Lys Asp Val Ala Leu Ser Ser Gly Arg 
        35                  40                  45


<210>  9849
<211>  529
<212>  DNA
<213>  Homo sapiens

<400>  9849
agcacttccg ggagcctggg gcccaggact gcagcggctt cggaaggtgg gctctgccag     60

cgggaccatg ctgctccgag ccgcttggag gcgggcggca gtggcggtga cagcggctcc    120

agggccgaag cccgcggcgc ccactcgggg gctgcgcctg cgcgttggag accgtgctcc    180

tcagtctgcg gttcccgcag atacagccgc tgccccggag gtggggccag tgctgcgacc    240

tcccaaagtg ccccacaacc atttttactt actgatacat ggtctcattc tgtcacctag    300

gctggggtgc agttgcacaa tcacagctca ctggagcctt gaactcctgg actcaagcaa    360

tcctctcatc ttagcctccc aagtagctag gcttacaggc gtgtactagc acgcctgtct    420

aattttgtta ttttaattta tttatttatt tttttttgag atggagcctg gctctgtcgc    480

ccaggctgga gtgcagtggc gtgatctcag ctcactgcaa gctctgcct                529


<210>  9850
<211>  113
<212>  PRT
<213>  Homo sapiens

<400>  9850

Met Leu Leu Arg Ala Ala Trp Arg Arg Ala Ala Val Ala Val Thr Ala 
1               5                   10                  15


Ala Pro Gly Pro Lys Pro Ala Ala Pro Thr Arg Gly Leu Arg Leu Arg 
            20                  25                  30


Val Gly Asp Arg Ala Pro Gln Ser Ala Val Pro Ala Asp Thr Ala Ala 
        35                  40                  45


Ala Pro Glu Val Gly Pro Val Leu Arg Pro Pro Lys Val Pro His Asn 
    50                  55                  60


His Phe Tyr Leu Leu Ile His Gly Leu Ile Leu Ser Pro Arg Leu Gly 
65                  70                  75                  80


Cys Ser Cys Thr Ile Thr Ala His Trp Ser Leu Glu Leu Leu Asp Ser 
                85                  90                  95


Ser Asn Pro Leu Ile Leu Ala Ser Gln Val Ala Arg Leu Thr Gly Val 
            100                 105                 110


Tyr 



<210>  9851
<211>  789
<212>  DNA
<213>  Homo sapiens

<400>  9851
agcacttccg ggagcctggg gcccaggact gcagcggctt cggaaggtgg gctctgccag     60

cgggaccatg ctgctccgag ccgcttggag gcgggcggca gtggcggtga cagcggctcc    120

agggccgaag cccgcggcgc ccactcgggg gctgcgcctg cgcgttggag accgtgctcc    180

tcagtctgcg gttcccgcag atacagccgc tgccccggag gtggggccag tgctgcgacc    240

tctctatatg gatgtgcaag ctacaactcc tctggacccc cgggtgcttg atgccatgct    300

cccttaccta atcaactact atgggaaccc acactcccgg acacatgctt atggctggga    360

gagtgaggca gccatggaac gtgctcgtca gcaagtagca tctctgattg gagctgatcc    420

tcgtgagatc atttttacta gtggtgctac tgaatccaac aacatagcaa ttaagactga    480

gtctcactct gtcatccagg ctggagtgca gtggcacgat cttgactcac tgcaagctcc    540

gcctcctggg ttcacgccat tctcctgcct cagcctcctg agtagctggg actacaggcg    600

ccctccacca cacccggcta attttttgta tttttagtag agacagggtt tcactgtgtt    660

agccagaatg gtctcgatct cctgacctcg tgatccgccc tcctcggcct cccaaagtgc    720

cccacaacca tttttactta ctgatgtaaa tactttttag gataaaatag agtataaatc    780

aattataaa                                                            789


<210>  9852
<211>  189
<212>  PRT
<213>  Homo sapiens

<400>  9852

Met Leu Leu Arg Ala Ala Trp Arg Arg Ala Ala Val Ala Val Thr Ala 
1               5                   10                  15


Ala Pro Gly Pro Lys Pro Ala Ala Pro Thr Arg Gly Leu Arg Leu Arg 
            20                  25                  30


Val Gly Asp Arg Ala Pro Gln Ser Ala Val Pro Ala Asp Thr Ala Ala 
        35                  40                  45


Ala Pro Glu Val Gly Pro Val Leu Arg Pro Leu Tyr Met Asp Val Gln 
    50                  55                  60


Ala Thr Thr Pro Leu Asp Pro Arg Val Leu Asp Ala Met Leu Pro Tyr 
65                  70                  75                  80


Leu Ile Asn Tyr Tyr Gly Asn Pro His Ser Arg Thr His Ala Tyr Gly 
                85                  90                  95


Trp Glu Ser Glu Ala Ala Met Glu Arg Ala Arg Gln Gln Val Ala Ser 
            100                 105                 110


Leu Ile Gly Ala Asp Pro Arg Glu Ile Ile Phe Thr Ser Gly Ala Thr 
        115                 120                 125


Glu Ser Asn Asn Ile Ala Ile Lys Thr Glu Ser His Ser Val Ile Gln 
    130                 135                 140


Ala Gly Val Gln Trp His Asp Leu Asp Ser Leu Gln Ala Pro Pro Pro 
145                 150                 155                 160


Gly Phe Thr Pro Phe Ser Cys Leu Ser Leu Leu Ser Ser Trp Asp Tyr 
                165                 170                 175


Arg Arg Pro Pro Pro His Pro Ala Asn Phe Leu Tyr Phe 
            180                 185


<210>  9853
<211>  464
<212>  DNA
<213>  Homo sapiens

<400>  9853
acgctcgggt cccgctctcc gggaggcgcg gacctgtccc ctccgcgcgg cgacgcaact     60

gaatattccg gagccttcct gtccaccctg ctgcccagac cctctgaccc ttctctcaaa    120

tgacacatcc ctcaaacttt cttaggcggg tccccgaacg gttgaccccg gcgcaccacc    180

cctcgcaccc tgcgcgacag gcccccagag ccgtggaggc gcgtccttca gaccgctcct    240

ggccaagtta cagatgctgc tccgggctcc cgtgcagacc gttaccttcg gtcagaaggg    300

actgcaccta ctctggctcc acgttccttc taaacgtctt tgccctttag agccttcctt    360

cctacgatac catttgaata tcaactcaac accccctcca ggaaccctct ctccctctcc    420

cttacctcct tttacagcgt gtcagttgga gaccgtgctc ctca                     464


<210>  9854
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  9854

Met Leu Leu Arg Ala Pro Val Gln Thr Val Thr Phe Gly Gln Lys Gly 
1               5                   10                  15


Leu His Leu Leu Trp Leu His Val Pro Ser Lys Arg Leu Cys Pro Leu 
            20                  25                  30


Glu Pro Ser Phe Leu Arg Tyr His Leu Asn Ile Asn Ser Thr Pro Pro 
        35                  40                  45


Pro Gly Thr Leu Ser Pro Ser Pro Leu Pro Pro Phe Thr Ala Cys Gln 
    50                  55                  60


Leu Glu Thr Val Leu 
65


<210>  9855
<211>  502
<212>  DNA
<213>  Homo sapiens

<400>  9855
gcggctcgga gcagcatggt cccgctggca gagcccacct tccgaagccg ctgcagtcct     60

gggccccagg ctcccggaag tgctgcccgg cgctccggaa gcgattcatc gggccgcgag    120

cgccctcccc gtcgttttcc gtgagagacg tagagctgag cgacccagcc cgcgagcgag    180

gtgagatgcc ggtggccgtg ggtccctacg gacagtccca gccaagctgc ttcgaccgtg    240

tcaaaatggg cttcgtgatg ggttgcgccg tgggcatggc ggccggggcg ctcttcggca    300

ccttttcctg tctcaggatc ggaatgcggg gtcgagagct gatgggcggc attgggaaaa    360

ccatgatgca gagtggcggc acctttggca cattcatggc cattgggatg ggcatccgat    420

gctaaccatg gttgccaact acatctgtcc cttcccatca atcccagccc atgtactaat    480

aaaagaaagt ctttgagtag tc                                             502


<210>  9856
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  9856

Met Pro Val Ala Val Gly Pro Tyr Gly Gln Ser Gln Pro Ser Cys Phe 
1               5                   10                  15


Asp Arg Val Lys Met Gly Phe Val Met Gly Cys Ala Val Gly Met Ala 
            20                  25                  30


Ala Gly Ala Leu Phe Gly Thr Phe Ser Cys Leu Arg Ile Gly Met Arg 
        35                  40                  45


Gly Arg Glu Leu Met Gly Gly Ile Gly Lys Thr Met Met Gln Ser Gly 
    50                  55                  60


Gly Thr Phe Gly Thr Phe Met Ala Ile Gly Met Gly Ile Arg Cys 
65                  70                  75


<210>  9857
<211>  519
<212>  DNA
<213>  Homo sapiens

<400>  9857
gcggctcgga gcagcatggt cccgctggca gagcccacct tccgaagccg ctgcagtcct     60

gggccccagg ctcccggaag tgctgcccgg cgctccggaa gcgattcatc gggccgcgag    120

cgccctcccc gtcgttttcc gtgagagacg tagagctgag cgacccagcc cgcgagcgag    180

gtgagatgcc ggtggccgtg ggtccctacg gacagtccca gccaagctgc ttcgaccgtg    240

tcaaaatggg cttcgtgatg ggttgcgccg tgggcatggc ggccggggcg ctcttcggca    300

ccttttcctg tctcaggatc ggaatgcggg gtcgagagct gatgggcggc attgggaaaa    360

ccatgatgca gagtggcggc acctttggca cattcatggc cattgggatg ggcatccgat    420

gctaaccatg gttgccaact acatctgtcc cttcccatca atcccagccc atgtactaat    480

aaaagaaagt ctttgagtag tcagtgtccc tctcttaaa                           519


<210>  9858
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  9858

Met Pro Val Ala Val Gly Pro Tyr Gly Gln Ser Gln Pro Ser Cys Phe 
1               5                   10                  15


Asp Arg Val Lys Met Gly Phe Val Met Gly Cys Ala Val Gly Met Ala 
            20                  25                  30


Ala Gly Ala Leu Phe Gly Thr Phe Ser Cys Leu Arg Ile Gly Met Arg 
        35                  40                  45


Gly Arg Glu Leu Met Gly Gly Ile Gly Lys Thr Met Met Gln Ser Gly 
    50                  55                  60


Gly Thr Phe Gly Thr Phe Met Ala Ile Gly Met Gly Ile Arg Cys 
65                  70                  75


<210>  9859
<211>  535
<212>  DNA
<213>  Homo sapiens

<400>  9859
gagacgtaga gctgagcgac ccagcccgcg agcgaggtga ggtaggcgcc gggcgacgcg     60

gggccggaac gcgaagaggg tggtggagtc gggctaccca ctgattttcc ttcccttact    120

tcccctgagc ccttgggccc acttcccagc ctaccgcttc cgtccccgcc cgactcttgg    180

gccagcgcct gggcccacac tttcctatcc cccgcagatg ccggtggccg tgggtcccta    240

cggacagtcc cagccaagct gcttcgaccg tgtcaaaatg ggcttcgtga tgggttgcgc    300

cgtgggcatg gcggccgggg cgctcttcgg caccttttcc tgtctcagga tcggaatgcg    360

gggtcgagag ctgatgggcg gcattgggaa aaccatgatg cagagtggcg gcacctttgg    420

cacattcatg gccattggga tgggcatccg atgctaacca tggttgccaa ctacatctgt    480

cccttcccat caatcccagc ccatgtacta ataaaagaaa gtctttgagt agtca         535


<210>  9860
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  9860

Met Pro Val Ala Val Gly Pro Tyr Gly Gln Ser Gln Pro Ser Cys Phe 
1               5                   10                  15


Asp Arg Val Lys Met Gly Phe Val Met Gly Cys Ala Val Gly Met Ala 
            20                  25                  30


Ala Gly Ala Leu Phe Gly Thr Phe Ser Cys Leu Arg Ile Gly Met Arg 
        35                  40                  45


Gly Arg Glu Leu Met Gly Gly Ile Gly Lys Thr Met Met Gln Ser Gly 
    50                  55                  60


Gly Thr Phe Gly Thr Phe Met Ala Ile Gly Met Gly Ile Arg Cys 
65                  70                  75


<210>  9861
<211>  359
<212>  DNA
<213>  Homo sapiens

<400>  9861
gaggtaggcg ccgggcgacg cggggccgga acgcgaagag gatgccggtg gccgtgggtc     60

cctacggaca gtcccagcca agctgcttcg accgtgtcaa aatgggcttc gtgatgggtt    120

gcgccgtggg catggcggcc ggggcgctct tcggcacctt ttcctgtctc aggatcggaa    180

tgcggggtcg agagctgatg ggcggcattg ggaaaaccat gatgcagagt ggcggcacct    240

ttggcacatt catggccatt gggatgggca tccgatgcta accatggttg ccaactacat    300

ctgtcccttc ccatcaatcc cagcccatgt actaataaaa gaaagtcttt gagtagtca     359


<210>  9862
<211>  79
<212>  PRT
<213>  Homo sapiens

<400>  9862

Met Pro Val Ala Val Gly Pro Tyr Gly Gln Ser Gln Pro Ser Cys Phe 
1               5                   10                  15


Asp Arg Val Lys Met Gly Phe Val Met Gly Cys Ala Val Gly Met Ala 
            20                  25                  30


Ala Gly Ala Leu Phe Gly Thr Phe Ser Cys Leu Arg Ile Gly Met Arg 
        35                  40                  45


Gly Arg Glu Leu Met Gly Gly Ile Gly Lys Thr Met Met Gln Ser Gly 
    50                  55                  60


Gly Thr Phe Gly Thr Phe Met Ala Ile Gly Met Gly Ile Arg Cys 
65                  70                  75


<210>  9863
<211>  1774
<212>  DNA
<213>  Homo sapiens

<400>  9863
gctgggatta caggcatgag tcaccgcgcc cggcctcatt gaaaatttat ttttcaatac     60

cagactgcag tgttctttgg ggcagagacg ttctgtcaat gtgctttttt tccaaagtat    120

tttttttaat tcatagaata tttaaatttt ttgatacatt tgtaaatata tagtttgtta    180

gtttcaatag tatttaagag tccttaatac tttcttacag agaagaagaa gttggatggg    240

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata    300

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg    360

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag    420

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac    480

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt    540

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg    600

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagga    660

atgcagtgtg ctcattctcc ctaaatagta aatcccactg tatacaaaac tgttctcttg    720

ttctgccttt taaaatgttc atgtagaaaa ttaatgaact ataggaatag ctctaggaga    780

acaaatgtgc tttctgtaaa aaggcagacc agggatgtaa tgtttttaat gtttcagaag    840

cctaactttt tacacagtgg ttacatttca catttcacta atgttgatat ttggctgatg    900

gttgagcagt ttctgaaata cacatttagt gtatggaaat acaagacagc taaagggctg    960

tttggttagc atctcatctt gcattctgat caattggcaa gaaagggaga tttcaaaatt   1020

atatttcttg atggtatctt ttcaattaat gtatctgtaa aagtttcttt gtaaatacta   1080

tgtgttctgg tgtgtcttaa aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt   1140

taaacgtgag agtctggtag gcaaagcagt ctgagaaaga aataggaaat gcagaaatag   1200

gttttgtctg gttgcatata atctttgctc tttttaagct ctgtgagctc tgaaatatat   1260

ttttgggtta cttcagtgtg tttgacaaga cagcttgata tttctatcaa acaaatgact   1320

ttcatattgc aacaatcttt gtaagaacca ctcaaataaa agtctcttaa aaaggccaca   1380

ggagatcttc atttttcaaa tgttttaaag ttacagaaat ttgagaacag aattagcttc   1440

ttttagtctc aattcagtac ttgcctcttg ggaaaatgtt ccgagtctgc ggaaacttgc   1500

cctcacgttg tcccccatga attcctttat tctattagag tctagccctg tgtattttag   1560

aagaatgtat caaaactgag gggtttacca aaaagaaaag gaaacagcct ggccttaaaa   1620

cctgggcatt cttggtctcc tgcattgtct gggcatattt atgaagaaat tttcaccatt   1680

tacaatacat acttaacaaa atggcttaac ttcaaactgg tttccaaaat tgatttatat   1740

attaatatat taaataaggt gcatatatta ctgt                               1774


<210>  9864
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  9864

Met Asn Tyr Arg Asn Ser Ser Arg Arg Thr Asn Val Leu Ser Val Lys 
1               5                   10                  15


Arg Gln Thr Arg Asp Val Met Phe Leu Met Phe Gln Lys Pro Asn Phe 
            20                  25                  30


Leu His Ser Gly Tyr Ile Ser His Phe Thr Asn Val Asp Ile Trp Leu 
        35                  40                  45


Met Val Glu Gln Phe Leu Lys Tyr Thr Phe Ser Val Trp Lys Tyr Lys 
    50                  55                  60


Thr Ala Lys Gly Leu Phe Gly 
65                  70


<210>  9865
<211>  2403
<212>  DNA
<213>  Homo sapiens

<400>  9865
atgaaatttg gtcagataat atgattacgg tgagttctgt aacagctact ggtaatattt     60

ttgtaaatca cgtgaaagca ttggagcaac tgtcttggaa aatgctcttt aaacttcaaa    120

ccccagtatg ttttggtagt agtggatatt acacatatat gctgctcttt tcagtgttct    180

tttattgtgc gaaaacattt ttaaaacatt tgatttatta ataggattta tttttaatag    240

gattgttaat aggatttatt tttctaggac attgtcttta aacacttgga tgattttata    300

tgtcttaatt ctttaataat ttgtagattt aaaaaacttc gtgggcagaa agcgaagaaa    360

taggaaagga tatagattta tttggcattt caaaggattt tgttttatta tcccctctta    420

tttgggtata aactcaaatc tattttatcc ttcatctgtt tggattgatg tgtattgaga    480

ttttgtctaa ttgaactgat tttgataaca cataaagttt aatttccctg ttaaaatagg    540

actcccaaat ttctgaatgt ctgtttcaag tattaggtta cctcagtttt ctggcaccta    600

aaagctactg ataacataca ttagtagcaa tattaaataa ggtaaaataa ctccagtgac    660

atcctagtta catgcttggg gtgggttttt ggtttcgttt taaagtattt atgagggata    720

ctttcatgca ttttccatga aactaatttt tctctttctt tttttagctt cagctttagc    780

tgcagctgcc tctgttcagc cacttgcaac acaatgtttc caactctcta acatgtttaa    840

ccctcaaaca gaagaagaag ttggatggga taccgagatt aaggatgatg tgattgaaga    900

atgtaataaa catggaggag ttattcatat ttatgttgac aaaaattcag ctcagggcaa    960

tgtgtatgtg aagtgcccat caattgctgc agctattgct gctgtcaatg cattgcatgg   1020

caggtggttt gctggtaaaa tgataacagc agcatatgta cctcttccaa cttaccacaa   1080

cctgtttcct gattctatga cagcaacaca gctactggtt ccaagtagac gatgaaggaa   1140

gatatagtcc cttatgtata tagctttttt tctttcttga gaattcatct tgagttatct   1200

tttatttaga taaaaataaa gaggcaagga tctactgtca tttgtatgca atttcctgtt   1260

accttgaaaa aataaaaatg ttaacaggaa tgcagtgtgc tcattctccc taaatagtaa   1320

atcccactgt atacaaaact gttctcttgt tctgcctttt aaaatgttca tgtagaaaat   1380

taatgaacta taggaatagc tctaggagaa caaatgtgct ttctgtaaaa aggcagacca   1440

gggatgtaat gtttttaatg tttcagaagc ctaacttttt acacagtggt tacatttcac   1500

atttcactaa tgttgatatt tggctgatgg ttgagcagtt tctgaaatac acatttagtg   1560

tatggaaata caagacagct aaagggctgt ttggttagca tctcatcttg cattctgatc   1620

aattggcaag aaagggagat ttcaaaatta tatttcttga tggtatcttt tcaattaatg   1680

tatctgtaaa agtttctttg taaatactat gtgttctggt gtgtcttaaa attccaaaca   1740

aaatgatccc tgcatttcct gaagatgttt aaacgtgaga gtctggtagg caaagcagtc   1800

tgagaaagaa ataggaaatg cagaaatagg ttttgtctgg ttgcatataa tctttgctct   1860

ttttaagctc tgtgagctct gaaatatatt tttgggttac ttcagtgtgt ttgacaagac   1920

agcttgatat ttctatcaaa caaatgactt tcatattgca acaatctttg taagaaccac   1980

tcaaataaaa gtctcttaaa aaggccacag gagatcttca tttttcaaat gttttaaagt   2040

tacagaaatt tgagaacaga attagcttct tttagtctca attcagtact tgcctcttgg   2100

gaaaatgttc cgagtctgcg gaaacttgcc ctcacgttgt cccccatgaa ttcctttatt   2160

ctattagagt ctagccctgt gtattttaga agaatgtatc aaaactgagg ggtttaccaa   2220

aaagaaaagg aaacagcctg gccttaaaac ctgggcattc ttggtctcct gcattgtctg   2280

ggcatattta tgaagaaatt ttcaccattt acaatacata cttaacaaaa tggcttaact   2340

tcaaactggt ttccaaaatt gatttatata ttaatatatt aaataaggtg catatattac   2400

tgt                                                                 2403


<210>  9866
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  9866

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys 
65                  70                  75                  80


Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg 
                85                  90                  95


Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr 
            100                 105                 110


Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val 
        115                 120                 125


Pro Ser Arg Arg 
    130


<210>  9867
<211>  3494
<212>  DNA
<213>  Homo sapiens

<400>  9867
attatgagaa agatatgtca tgttccatca cagtcaagaa ttaaattttt tcacaaacaa     60

gatgcttcta atcagtgctg ttttgttaag agatttttaa aagattttcc tagatttact    120

gtgttctgca ttgatctagc ttgaacgtga atgtttgtat agtacgtttt cttaatattt    180

tttagtattc atagtatata atcatactaa acttgagaaa ctggaagaat caagtcttcc    240

tcagttctgt ttagactttc tagttttttt taaggatact tccatatctt ctgtaagcta    300

cacagtgagc ttcatttttg cacagttata atacactctc gaatctttaa cttttttcca    360

gcagaatttg acatgttata ttaaaatttt gttttattta aaataaaact ttatgaaaga    420

aaaaacttat atgttacaga gaagctaaag cacctgtaat gctaccagaa agttatcatt    480

tatgatatat ttcatgcaca gccctaattt ctcggtgtaa tatttctgat actttaagtg    540

atcgtttatt ttaattacca taatttctaa tgcactgttt tatccttagc tttgtttgtt    600

attatgtttt ggaatgaaat ttggtcagat aatatgatta cggtgagttc tgtaacagct    660

actggtaata tttttgtaaa tcacgtgaaa gcattggagc aactgtcttg gaaaatgctc    720

tttaaacttc aaaccccagt atgttttggt agtagtggat attacacata tatgctgctc    780

ttttcagtgt tcttttattg tgcgaaaaca tttttaaaac atttgattta ttaataggat    840

ttatttttaa taggattgtt aataggattt atttttctag gacattgtct ttaaacactt    900

ggatgatttt atatgtctta attctttaat aatttgtaga tttaaaaaac ttcgtgggca    960

gaaagcgaag aaataggaaa ggatatagat ttatttggca tttcaaagga ttttgtttta   1020

ttatcccctc ttatttgggt ataaactcaa atctatttta tccttcatct gtttggattg   1080

atgtgtattg agattttgtc taattgaact gattttgata acacataaag tttaatttcc   1140

ctgttaaaat aggactccca aatttctgaa tgtctgtttc aagtattagg ttacctcagt   1200

tttctggcac ctaaaagcta ctgataacat acattagtag caatattaaa taaggtaaaa   1260

taactccagt gacatcctag ttacatgctt ggggtgggtt tttggtttcg ttttaaagta   1320

tttatgaggg atactttcat gcattttcca tgaaactaat ttttctcttt ctttttttag   1380

cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct   1440

ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg   1500

atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt   1560

cagctcaggt attttcatct ttttttataa atgatgttag gttgttcgtc tctaccttaa   1620

tcttcgcaca ttatgtggtg catgttatgg ttaaccgtct tccattatag tttttgtgtg   1680

tgtgtgcctg aaagtagctt taatatagtg gctaaataaa ccctccaaaa taaaagaaaa   1740

tcagtaacaa tttgatcagg gtatgagagg atttctagta atgctcaaag cttgccatga   1800

aatcttggca tcttgattca ttcttaggct gcatacaaat cgtagagaaa agataaaacg   1860

gcaaatttga gagtagaagt cattttttaa taaaattcta gtatacctat tagccagtgg   1920

aaccattatg gtaaaccagt ttgtggttat agagcactaa gtttctacag gcaacttgaa   1980

taaacataac ttgggtccat tttgcataca gcaacatctt tacctttttt ttcatttttt   2040

ctgtagggca atgtgtatgt gaagtgccca tcaattgctg cagctattgc tgctgtcaat   2100

gcattgcatg gcaggtggtt tgctggtaaa atgataacag cagcatatgt acctcttcca   2160

acttaccaca acctgtttcc tgattctatg acagcaacac agctactggt tccaagtaga   2220

cgatgaagga agatatagtc ccttatgtat atagcttttt ttctttcttg agaattcatc   2280

ttgagttatc ttttatttag ataaaaataa agaggcaagg atctactgtc atttgtatgc   2340

aatttcctgt taccttgaaa aaataaaaat gttaacagga atgcagtgtg ctcattctcc   2400

ctaaatagta aatcccactg tatacaaaac tgttctcttg ttctgccttt taaaatgttc   2460

atgtagaaaa ttaatgaact ataggaatag ctctaggaga acaaatgtgc tttctgtaaa   2520

aaggcagacc agggatgtaa tgtttttaat gtttcagaag cctaactttt tacacagtgg   2580

ttacatttca catttcacta atgttgatat ttggctgatg gttgagcagt ttctgaaata   2640

cacatttagt gtatggaaat acaagacagc taaagggctg tttggttagc atctcatctt   2700

gcattctgat caattggcaa gaaagggaga tttcaaaatt atatttcttg atggtatctt   2760

ttcaattaat gtatctgtaa aagtttcttt gtaaatacta tgtgttctgg tgtgtcttaa   2820

aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt taaacgtgag agtctggtag   2880

gcaaagcagt ctgagaaaga aataggaaat gcagaaatag gttttgtctg gttgcatata   2940

atctttgctc tttttaagct ctgtgagctc tgaaatatat ttttgggtta cttcagtgtg   3000

tttgacaaga cagcttgata tttctatcaa acaaatgact ttcatattgc aacaatcttt   3060

gtaagaacca ctcaaataaa agtctcttaa aaaggccaca ggagatcttc atttttcaaa   3120

tgttttaaag ttacagaaat ttgagaacag aattagcttc ttttagtctc aattcagtac   3180

ttgcctcttg ggaaaatgtt ccgagtctgc ggaaacttgc cctcacgttg tcccccatga   3240

attcctttat tctattagag tctagccctg tgtattttag aagaatgtat caaaactgag   3300

gggtttacca aaaagaaaag gaaacagcct ggccttaaaa cctgggcatt cttggtctcc   3360

tgcattgtct gggcatattt atgaagaaat tttcaccatt tacaatacat acttaacaaa   3420

atggcttaac ttcaaactgg tttccaaaat tgatttatat attaatatat taaataaggt   3480

gcatatatta ctgt                                                     3494


<210>  9868
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  9868

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Val Phe Ser Ser Phe Phe Ile 
65                  70                  75                  80


Asn Asp Val Arg Leu Phe Val Ser Thr Leu Ile Phe Ala His Tyr Val 
                85                  90                  95


Val His Val Met Val Asn Arg Leu Pro Leu 
            100                 105


<210>  9869
<211>  1946
<212>  DNA
<213>  Homo sapiens

<400>  9869
gggatttaag tgaaccacct cccttggcct cccagagtgc tagctaagtt acaggcgtca     60

accaccacac tcggccctcc ttgcaattta ttttagtgaa gtgatcatga tattaatgac    120

ccaggaaact tcgtttctct gctctcaaca tagtaggaac tttaagacta ttcttttaca    180

ggtacaggtt tgcagattcc gccagcagca cagcaagctc tacagatgag tggctctttg    240

gcatttggtg ctgtggcaga attctctttt gttatagatt tgcaaacaag actttcccag    300

cagactgaag cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt    360

ttccaactct ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag    420

attaaggatg atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt    480

gacaaaaatt cagctcaggg caatgtgtat gtgaagtgcc catcaattgc tgcagctatt    540

gctgctgtca atgcattgca tggcaggtgg tttgctggta aaatgataac agcagcatat    600

gtacctcttc caacttacca caacctgttt cctgattcta tgacagcaac acagctactg    660

gttccaagta gacgatgaag gaagatatag tcccttatgt atatagcttt ttttctttct    720

tgagaattca tcttgagtta tcttttattt agataaaaat aaagaggcaa ggatctactg    780

tcatttgtat gcaatttcct gttaccttga aaaaataaaa atgttaacag gaatgcagtg    840

tgctcattct ccctaaatag taaatcccac tgtatacaaa actgttctct tgttctgcct    900

tttaaaatgt tcatgtagaa aattaatgaa ctataggaat agctctagga gaacaaatgt    960

gctttctgta aaaaggcaga ccagggatgt aatgttttta atgtttcaga agcctaactt   1020

tttacacagt ggttacattt cacatttcac taatgttgat atttggctga tggttgagca   1080

gtttctgaaa tacacattta gtgtatggaa atacaagaca gctaaagggc tgtttggtta   1140

gcatctcatc ttgcattctg atcaattggc aagaaaggga gatttcaaaa ttatatttct   1200

tgatggtatc ttttcaatta atgtatctgt aaaagtttct ttgtaaatac tatgtgttct   1260

ggtgtgtctt aaaattccaa acaaaatgat ccctgcattt cctgaagatg tttaaacgtg   1320

agagtctggt aggcaaagca gtctgagaaa gaaataggaa atgcagaaat aggttttgtc   1380

tggttgcata taatctttgc tctttttaag ctctgtgagc tctgaaatat atttttgggt   1440

tacttcagtg tgtttgacaa gacagcttga tatttctatc aaacaaatga ctttcatatt   1500

gcaacaatct ttgtaagaac cactcaaata aaagtctctt aaaaaggcca caggagatct   1560

tcatttttca aatgttttaa agttacagaa atttgagaac agaattagct tcttttagtc   1620

tcaattcagt acttgcctct tgggaaaatg ttccgagtct gcggaaactt gccctcacgt   1680

tgtcccccat gaattccttt attctattag agtctagccc tgtgtatttt agaagaatgt   1740

atcaaaactg aggggtttac caaaaagaaa aggaaacagc ctggccttaa aacctgggca   1800

ttcttggtct cctgcattgt ctgggcatat ttatgaagaa attttcacca tttacaatac   1860

atacttaaca aaatggctta acttcaaact ggtttccaaa attgatttat atattaatat   1920

attaaataag gtgcatatat tactgt                                        1946


<210>  9870
<211>  150
<212>  PRT
<213>  Homo sapiens

<400>  9870

Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val 
1               5                   10                  15


Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu 
            20                  25                  30


Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu 
        35                  40                  45


Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr 
    50                  55                  60


Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val 
65                  70                  75                  80


Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val 
                85                  90                  95


Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His 
            100                 105                 110


Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu 
        115                 120                 125


Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu 
    130                 135                 140


Leu Val Pro Ser Arg Arg 
145                 150


<210>  9871
<211>  3454
<212>  DNA
<213>  Homo sapiens

<400>  9871
attctattgt aagtttgttt tattaattta ttttgtggat tacagtaatg cttttgttgg     60

cctgttgtat gacaaactat ttaaaggttc acattttgat ttgtatttgc caacaagccc    120

ttttgcttgt taaagctata gctaactctc aggagataat tgcagttcta ctcttagagg    180

atggtgtctt tcaaataatg tcttgtctgc tgattttcag taatgttaat ataaggcaaa    240

agggatattg tttactatac gtagcaattt ttttagacag agtcttactc tgtcgcccag    300

gctggagtac cagtggcggg atcttggctc actgcaacct ccgcttcccg ggtttgagca    360

attctcctgc cttagcctcc cgagtagctg ggactacagg cgcacggtac tatgcccggc    420

taatttttgt atttttatta gggacggggt ttcactacat tggccagact ggtcttgaac    480

tcctgacctt gtgatctgcc tgcctcggcc taccaaagtg ctgagattac aggatttttt    540

ttttttttta agtatgatta tgtaccattg tatcatagta aaactagcca aagaaattta    600

tgaaaggatg aaaaaatgat tctggccata aaaggtagta tattttggtg ggttcttaag    660

ccagcatgat aatggcgagt ttttttcttc tcaggaggaa aaaaagcaag agcagaagtc    720

gtagtcatga acgaaagaga agcaaaagta aggaacggaa gcgaagtaga gacagagaaa    780

ggaaaaagag caaaagccgt gaaagaaagc gaagtagaag caaagagagg cgacggagcc    840

gctcaagaag tcgagatcga agatttagag gccgctacag aagtccttac tccggaccaa    900

aatttaacag tgccatccga ggaaagattg ggttgcctca tagcatcaaa ttaagcagac    960

gacgttcccg aagcaaaagt ccattcagaa aagacaagag ccctgtgaga gaacctattg   1020

ataatttaac tcctgaggaa agagatgcaa ggacagtctt ctgtatgcag ctggcggcaa   1080

gaattcgacc aagggatttg gaagagtttt tctctacagt aggaaaggtt cgagatgtga   1140

ggatgatttc tgacagaaat tcaagacgtt ccaaaggaat tgcttatgtg gagttcgtcg   1200

atgttagctc agtgcctcta gcaataggat taactggcca acgagtttta ggcgtgccaa   1260

tcatagtaca ggcatcacag gcagaaaaaa acagagctgc agcaatggca aacaatttac   1320

aaaagggaag tgctggacct atgaggcttt atgtgggctc attacacttc aacataactg   1380

aagatatgct tcgtgggatc tttgagcctt ttggaagaat tgaaagtatc cagctgatga   1440

tggacagtga aactggtcga tccaagggat atggatttat tacattttct gactcagaat   1500

gtgccaaaaa ggctttggaa caacttaatg gatttgaact agcaggaaga ccaatgaaag   1560

ttggtcatgt tactgaacgt actgatgctt cgagtgctag ttcatttttg gacagtgatg   1620

aactggaaag gactggaatt gatttgggaa caactggtcg tcttcagtta atggcaagac   1680

ttgcagaggg tacaggtttg cagattccgc cagcagcaca gcaagctcta cagatgagtg   1740

gctctttggc atttggtgct gtggcagaat tctcttttgt tatagatttg caaacaagac   1800

tttcccagca gactgaagct tcagctttag ctgcagctgc ctctgttcag ccacttgcaa   1860

cacaatgttt ccaactctct aacatgttta accctcaaac agaagaagaa gttggatggg   1920

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata   1980

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg   2040

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag   2100

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac   2160

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt   2220

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg   2280

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagga   2340

atgcagtgtg ctcattctcc ctaaatagta aatcccactg tatacaaaac tgttctcttg   2400

ttctgccttt taaaatgttc atgtagaaaa ttaatgaact ataggaatag ctctaggaga   2460

acaaatgtgc tttctgtaaa aaggcagacc agggatgtaa tgtttttaat gtttcagaag   2520

cctaactttt tacacagtgg ttacatttca catttcacta atgttgatat ttggctgatg   2580

gttgagcagt ttctgaaata cacatttagt gtatggaaat acaagacagc taaagggctg   2640

tttggttagc atctcatctt gcattctgat caattggcaa gaaagggaga tttcaaaatt   2700

atatttcttg atggtatctt ttcaattaat gtatctgtaa aagtttcttt gtaaatacta   2760

tgtgttctgg tgtgtcttaa aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt   2820

taaacgtgag agtctggtag gcaaagcagt ctgagaaaga aataggaaat gcagaaatag   2880

gttttgtctg gttgcatata atctttgctc tttttaagct ctgtgagctc tgaaatatat   2940

ttttgggtta cttcagtgtg tttgacaaga cagcttgata tttctatcaa acaaatgact   3000

ttcatattgc aacaatcttt gtaagaacca ctcaaataaa agtctcttaa aaaggccaca   3060

ggagatcttc atttttcaaa tgttttaaag ttacagaaat ttgagaacag aattagcttc   3120

ttttagtctc aattcagtac ttgcctcttg ggaaaatgtt ccgagtctgc ggaaacttgc   3180

cctcacgttg tcccccatga attcctttat tctattagag tctagccctg tgtattttag   3240

aagaatgtat caaaactgag gggtttacca aaaagaaaag gaaacagcct ggccttaaaa   3300

cctgggcatt cttggtctcc tgcattgtct gggcatattt atgaagaaat tttcaccatt   3360

tacaatacat acttaacaaa atggcttaac ttcaaactgg tttccaaaat tgatttatat   3420

attaatatat taaataaggt gcatatatta ctgt                               3454


<210>  9872
<211>  506
<212>  PRT
<213>  Homo sapiens

<400>  9872

Met Ile Met Ala Ser Phe Phe Leu Leu Arg Arg Lys Lys Ser Lys Ser 
1               5                   10                  15


Arg Ser Arg Ser His Glu Arg Lys Arg Ser Lys Ser Lys Glu Arg Lys 
            20                  25                  30


Arg Ser Arg Asp Arg Glu Arg Lys Lys Ser Lys Ser Arg Glu Arg Lys 
        35                  40                  45


Arg Ser Arg Ser Lys Glu Arg Arg Arg Ser Arg Ser Arg Ser Arg Asp 
    50                  55                  60


Arg Arg Phe Arg Gly Arg Tyr Arg Ser Pro Tyr Ser Gly Pro Lys Phe 
65                  70                  75                  80


Asn Ser Ala Ile Arg Gly Lys Ile Gly Leu Pro His Ser Ile Lys Leu 
                85                  90                  95


Ser Arg Arg Arg Ser Arg Ser Lys Ser Pro Phe Arg Lys Asp Lys Ser 
            100                 105                 110


Pro Val Arg Glu Pro Ile Asp Asn Leu Thr Pro Glu Glu Arg Asp Ala 
        115                 120                 125


Arg Thr Val Phe Cys Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp 
    130                 135                 140


Leu Glu Glu Phe Phe Ser Thr Val Gly Lys Val Arg Asp Val Arg Met 
145                 150                 155                 160


Ile Ser Asp Arg Asn Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu 
                165                 170                 175


Phe Val Asp Val Ser Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln 
            180                 185                 190


Arg Val Leu Gly Val Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys 
        195                 200                 205


Asn Arg Ala Ala Ala Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly 
    210                 215                 220


Pro Met Arg Leu Tyr Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp 
225                 230                 235                 240


Met Leu Arg Gly Ile Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln 
                245                 250                 255


Leu Met Met Asp Ser Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile 
            260                 265                 270


Thr Phe Ser Asp Ser Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn 
        275                 280                 285


Gly Phe Glu Leu Ala Gly Arg Pro Met Lys Val Gly His Val Thr Glu 
    290                 295                 300


Arg Thr Asp Ala Ser Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu 
305                 310                 315                 320


Glu Arg Thr Gly Ile Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met 
                325                 330                 335


Ala Arg Leu Ala Glu Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln 
            340                 345                 350


Gln Ala Leu Gln Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu 
        355                 360                 365


Phe Ser Phe Val Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu 
    370                 375                 380


Ala Ser Ala Leu Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln 
385                 390                 395                 400


Cys Phe Gln Leu Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val 
                405                 410                 415


Gly Trp Asp Thr Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys 
            420                 425                 430


His Gly Gly Val Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly 
        435                 440                 445


Asn Val Tyr Val Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val 
    450                 455                 460


Asn Ala Leu His Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala 
465                 470                 475                 480


Tyr Val Pro Leu Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr 
                485                 490                 495


Ala Thr Gln Leu Leu Val Pro Ser Arg Arg 
            500                 505


<210>  9873
<211>  1638
<212>  DNA
<213>  Homo sapiens

<400>  9873
ggtgaatgtg agtacaggga agcagcggcc gccatttcag ggagcttgtc gacgctgtcg     60

caggggtgga tcctgagctg ccgaagccgc cgtcctgctc tcccgcgtgg gcttctctaa    120

ttccattgtt ttttttagat tctctcgggc ctagccgtcc ttggaacccg atattcgggc    180

tgggcggttc cgcggcctgg gcctagggtg cccatcaatt gctgcagcta ttgctgctgt    240

caatgcattg catggcaggt ggtttgctgg taaaatgata acagcagcat atgtacctct    300

tccaacttac cacaacctgt ttcctgattc tatgacagca acacagctac tggttccaag    360

tagacgatga aggaagatat agtcccttat gtatatagct ttttttcttt cttgagaatt    420

catcttgagt tatcttttat ttagataaaa ataaagaggc aaggatctac tgtcatttgt    480

atgcaatttc ctgttacctt gaaaaaataa aaatgttaac aggaatgcag tgtgctcatt    540

ctccctaaat agtaaatccc actgtataca aaactgttct cttgttctgc cttttaaaat    600

gttcatgtag aaaattaatg aactatagga atagctctag gagaacaaat gtgctttctg    660

taaaaaggca gaccagggat gtaatgtttt taatgtttca gaagcctaac tttttacaca    720

gtggttacat ttcacatttc actaatgttg atatttggct gatggttgag cagtttctga    780

aatacacatt tagtgtatgg aaatacaaga cagctaaagg gctgtttggt tagcatctca    840

tcttgcattc tgatcaattg gcaagaaagg gagatttcaa aattatattt cttgatggta    900

tcttttcaat taatgtatct gtaaaagttt ctttgtaaat actatgtgtt ctggtgtgtc    960

ttaaaattcc aaacaaaatg atccctgcat ttcctgaaga tgtttaaacg tgagagtctg   1020

gtaggcaaag cagtctgaga aagaaatagg aaatgcagaa ataggttttg tctggttgca   1080

tataatcttt gctcttttta agctctgtga gctctgaaat atatttttgg gttacttcag   1140

tgtgtttgac aagacagctt gatatttcta tcaaacaaat gactttcata ttgcaacaat   1200

ctttgtaaga accactcaaa taaaagtctc ttaaaaaggc cacaggagat cttcattttt   1260

caaatgtttt aaagttacag aaatttgaga acagaattag cttcttttag tctcaattca   1320

gtacttgcct cttgggaaaa tgttccgagt ctgcggaaac ttgccctcac gttgtccccc   1380

atgaattcct ttattctatt agagtctagc cctgtgtatt ttagaagaat gtatcaaaac   1440

tgaggggttt accaaaaaga aaaggaaaca gcctggcctt aaaacctggg cattcttggt   1500

ctcctgcatt gtctgggcat atttatgaag aaattttcac catttacaat acatacttaa   1560

caaaatggct taacttcaaa ctggtttcca aaattgattt atatattaat atattaaata   1620

aggtgcatat attactgt                                                 1638


<210>  9874
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  9874

Met Asn Tyr Arg Asn Ser Ser Arg Arg Thr Asn Val Leu Ser Val Lys 
1               5                   10                  15


Arg Gln Thr Arg Asp Val Met Phe Leu Met Phe Gln Lys Pro Asn Phe 
            20                  25                  30


Leu His Ser Gly Tyr Ile Ser His Phe Thr Asn Val Asp Ile Trp Leu 
        35                  40                  45


Met Val Glu Gln Phe Leu Lys Tyr Thr Phe Ser Val Trp Lys Tyr Lys 
    50                  55                  60


Thr Ala Lys Gly Leu Phe Gly 
65                  70


<210>  9875
<211>  3277
<212>  DNA
<213>  Homo sapiens

<400>  9875
tgtgtgtgtg tatgtgtgct ggtgaatgtg agtacaggga agcagcggcc gccatttcag     60

ggagcttgtc gacgctgtcg caggggtgga tcctgagctg ccgaagccgc cgtcctgctc    120

tcccgcgtgg gcttctctaa ttccattgtt ttttttagat tctctcgggc ctagccgtcc    180

ttggaacccg atattcgggc tgggcggttc cgcggcctgg gcctaggggc ttaacagtag    240

caacagaagc ggcggcggcg gcagcagcag cagcagcagc agcaatctct tcccgaacac    300

gagcaccaca ggcgcccgaa ggccggaaca ggcgtttaga gaaaatggca gacgatattg    360

atattgaagc aatgcttgag gctccttaca agaaggatga gaacaagttg agcagtgcca    420

acggccatga agaacgtagc aaaaaacaaa ctttctgcct ccttggaaag ctctacatct    480

ccttgtgatt ggagtgtggg tttcaagatt ccagaaggag gaaaaaaagc aagagcagaa    540

gtcgtagtca tgaacgaaag agaagcaaaa gtaaggaacg gaagcgaagt agagacagag    600

aaaggaaaaa gagcaaaagc cgtgaaagaa agcgaagtag aagcaaagag aggcgacgga    660

gccgctcaag aagtcgagat cgaagattta gaggccgcta cagaagtcct tactccggac    720

caaaatttaa cagtgccatc cgaggaaaga ttgggttgcc tcatagcatc aaattaagca    780

gacgacgttc ccgaagcaaa agtccattca gaaaagacaa gagccctgtg agagaaccta    840

ttgataattt aactcctgag gaaagagatg caaggacagt cttctgtatg cagctggcgg    900

caagaattcg accaagggat ttggaagagt ttttctctac agtaggaaag gttcgagatg    960

tgaggatgat ttctgacaga aattcaagac gttccaaagg aattgcttat gtggagttcg   1020

tcgatgttag ctcagtgcct ctagcaatag gattaactgg ccaacgagtt ttaggcgtgc   1080

caatcatagt acaggcatca caggcagaaa aaaacagagc tgcagcaatg gcaaacaatt   1140

tacaaaaggg aagtgctgga cctatgaggc tttatgtggg ctcattacac ttcaacataa   1200

ctgaagatat gcttcgtggg atctttgagc cttttggaag aattgaaagt atccagctga   1260

tgatggacag tgaaactggt cgatccaagg gatatggatt tattacattt tctgactcag   1320

aatgtgccaa aaaggctttg gaacaactta atggatttga actagcagga agaccaatga   1380

aagttggtca tgttactgaa cgtactgatg cttcgagtgc tagttcattt ttggacagtg   1440

atgaactgga aaggactgga attgatttgg gaacaactgg tcgtcttcag ttaatggcaa   1500

gacttgcaga gggtacaggt ttgcagattc cgccagcagc acagcaagct ctacagatga   1560

gtggctcttt ggcatttggt gctgtggcag aattctcttt tgttatagat ttgcaaacaa   1620

gactttccca gcagactgaa gcttcagctt tagctgcagc tgcctctgtt cagccacttg   1680

caacacaatg tttccaactc tctaacatgt ttaaccctca aacagaagaa gaagttggat   1740

gggataccga gattaaggat gatgtgattg aagaatgtaa taaacatgga ggagttattc   1800

atatttatgt tgacaaaaat tcagctcagg gcaatgtgta tgtgaagtgc ccatcaattg   1860

ctgcagctat tgctgctgtc aatgcattgc atggcaggtg gtttgctggt aaaatgataa   1920

cagcagcata tgtacctctt ccaacttacc acaacctgtt tcctgattct atgacagcaa   1980

cacagctact ggttccaagt agacgatgaa ggaagatata gtcccttatg tatatagctt   2040

tttttctttc ttgagaattc atcttgagtt atcttttatt tagataaaaa taaagaggca   2100

aggatctact gtcatttgta tgcaatttcc tgttaccttg aaaaaataaa aatgttaaca   2160

ggaatgcagt gtgctcattc tccctaaata gtaaatccca ctgtatacaa aactgttctc   2220

ttgttctgcc ttttaaaatg ttcatgtaga aaattaatga actataggaa tagctctagg   2280

agaacaaatg tgctttctgt aaaaaggcag accagggatg taatgttttt aatgtttcag   2340

aagcctaact ttttacacag tggttacatt tcacatttca ctaatgttga tatttggctg   2400

atggttgagc agtttctgaa atacacattt agtgtatgga aatacaagac agctaaaggg   2460

ctgtttggtt agcatctcat cttgcattct gatcaattgg caagaaaggg agatttcaaa   2520

attatatttc ttgatggtat cttttcaatt aatgtatctg taaaagtttc tttgtaaata   2580

ctatgtgttc tggtgtgtct taaaattcca aacaaaatga tccctgcatt tcctgaagat   2640

gtttaaacgt gagagtctgg taggcaaagc agtctgagaa agaaatagga aatgcagaaa   2700

taggttttgt ctggttgcat ataatctttg ctctttttaa gctctgtgag ctctgaaata   2760

tatttttggg ttacttcagt gtgtttgaca agacagcttg atatttctat caaacaaatg   2820

actttcatat tgcaacaatc tttgtaagaa ccactcaaat aaaagtctct taaaaaggcc   2880

acaggagatc ttcatttttc aaatgtttta aagttacaga aatttgagaa cagaattagc   2940

ttcttttagt ctcaattcag tacttgcctc ttgggaaaat gttccgagtc tgcggaaact   3000

tgccctcacg ttgtccccca tgaattcctt tattctatta gagtctagcc ctgtgtattt   3060

tagaagaatg tatcaaaact gaggggttta ccaaaaagaa aaggaaacag cctggcctta   3120

aaacctgggc attcttggtc tcctgcattg tctgggcata tttatgaaga aattttcacc   3180

atttacaata catacttaac aaaatggctt aacttcaaac tggtttccaa aattgattta   3240

tatattaata tattaaataa ggtgcatata ttactgt                            3277


<210>  9876
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9876

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9877
<211>  3246
<212>  DNA
<213>  Homo sapiens

<400>  9877
gcgagagccc gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc     60

tggtgaatgt gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc    120

gcaggggtgg atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta    180

attccattgt tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg    240

ctgggcggtt ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc    300

ggcagcagca gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga    360

aggccggaac aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga    420

ggctccttac aagaaggatg agaacaagtt gagcagtgcc aacggccatg aagaacgtag    480

caaaaagagg aaaaaaagca agagcagaag tcgtagtcat gaacgaaaga gaagcaaaag    540

taaggaacgg aagcgaagta gagacagaga aaggaaaaag agcaaaagcc gtgaaagaaa    600

gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga agtcgagatc gaagatttag    660

aggccgctac agaagtcctt actccggacc aaaatttaac agtgccatcc gaggaaagat    720

tgggttgcct catagcatca aattaagcag acgacgttcc cgaagcaaaa gtccattcag    780

aaaagacaag agccctgtga gagaacctat tgataattta actcctgagg aaagagatgc    840

aaggacagtc ttctgtatgc agctggcggc aagaattcga ccaagggatt tggaagagtt    900

tttctctaca gtaggaaagg ttcgagatgt gaggatgatt tctgacagaa attcaagacg    960

ttccaaagga attgcttatg tggagttcgt cgatgttagc tcagtgcctc tagcaatagg   1020

attaactggc caacgagttt taggcgtgcc aatcatagta caggcatcac aggcagaaaa   1080

aaacagagct gcagcaatgg caaacaattt acaaaaggga agtgctggac ctatgaggct   1140

ttatgtgggc tcattacact tcaacataac tgaagatatg cttcgtggga tctttgagcc   1200

ttttggaaga attgaaagta tccagctgat gatggacagt gaaactggtc gatccaaggg   1260

atatggattt attacatttt ctgactcaga atgtgccaaa aaggctttgg aacaacttaa   1320

tggatttgaa ctagcaggaa gaccaatgaa agttggtcat gttactgaac gtactgatgc   1380

ttcgagtgct agttcatttt tggacagtga tgaactggaa aggactggaa ttgatttggg   1440

aacaactggt cgtcttcagt taatggcaag acttgcagag ggtacaggtt tgcagattcc   1500

gccagcagca cagcaagctc tacagatgag tggctctttg gcatttggtg ctgtggcaga   1560

attctctttt gttatagatt tgcaaacaag actttcccag cagactgaag cttcagcttt   1620

agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct ctaacatgtt   1680

taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg atgtgattga   1740

agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt cagctcaggg   1800

caatgtgtat gtgaagtgcc catcaattgc tgcagctatt gctgctgtca atgcattgca   1860

tggcaggtgg tttgctggta aaatgataac agcagcatat gtacctcttc caacttacca   1920

caacctgttt cctgattcta tgacagcaac acagctactg gttccaagta gacgatgaag   1980

gaagatatag tcccttatgt atatagcttt ttttctttct tgagaattca tcttgagtta   2040

tcttttattt agataaaaat aaagaggcaa ggatctactg tcatttgtat gcaatttcct   2100

gttaccttga aaaaataaaa atgttaacag gaatgcagtg tgctcattct ccctaaatag   2160

taaatcccac tgtatacaaa actgttctct tgttctgcct tttaaaatgt tcatgtagaa   2220

aattaatgaa ctataggaat agctctagga gaacaaatgt gctttctgta aaaaggcaga   2280

ccagggatgt aatgttttta atgtttcaga agcctaactt tttacacagt ggttacattt   2340

cacatttcac taatgttgat atttggctga tggttgagca gtttctgaaa tacacattta   2400

gtgtatggaa atacaagaca gctaaagggc tgtttggtta gcatctcatc ttgcattctg   2460

atcaattggc aagaaaggga gatttcaaaa ttatatttct tgatggtatc ttttcaatta   2520

atgtatctgt aaaagtttct ttgtaaatac tatgtgttct ggtgtgtctt aaaattccaa   2580

acaaaatgat ccctgcattt cctgaagatg tttaaacgtg agagtctggt aggcaaagca   2640

gtctgagaaa gaaataggaa atgcagaaat aggttttgtc tggttgcata taatctttgc   2700

tctttttaag ctctgtgagc tctgaaatat atttttgggt tacttcagtg tgtttgacaa   2760

gacagcttga tatttctatc aaacaaatga ctttcatatt gcaacaatct ttgtaagaac   2820

cactcaaata aaagtctctt aaaaaggcca caggagatct tcatttttca aatgttttaa   2880

agttacagaa atttgagaac agaattagct tcttttagtc tcaattcagt acttgcctct   2940

tgggaaaatg ttccgagtct gcggaaactt gccctcacgt tgtcccccat gaattccttt   3000

attctattag agtctagccc tgtgtatttt agaagaatgt atcaaaactg aggggtttac   3060

caaaaagaaa aggaaacagc ctggccttaa aacctgggca ttcttggtct cctgcattgt   3120

ctgggcatat ttatgaagaa attttcacca tttacaatac atacttaaca aaatggctta   3180

acttcaaact ggtttccaaa attgatttat atattaatat attaaataag gtgcatatat   3240

tactgt                                                              3246


<210>  9878
<211>  530
<212>  PRT
<213>  Homo sapiens

<400>  9878

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Arg Lys Lys Ser Lys Ser Arg Ser Arg Ser His Glu Arg Lys 
        35                  40                  45


Arg Ser Lys Ser Lys Glu Arg Lys Arg Ser Arg Asp Arg Glu Arg Lys 
    50                  55                  60


Lys Ser Lys Ser Arg Glu Arg Lys Arg Ser Arg Ser Lys Glu Arg Arg 
65                  70                  75                  80


Arg Ser Arg Ser Arg Ser Arg Asp Arg Arg Phe Arg Gly Arg Tyr Arg 
                85                  90                  95


Ser Pro Tyr Ser Gly Pro Lys Phe Asn Ser Ala Ile Arg Gly Lys Ile 
            100                 105                 110


Gly Leu Pro His Ser Ile Lys Leu Ser Arg Arg Arg Ser Arg Ser Lys 
        115                 120                 125


Ser Pro Phe Arg Lys Asp Lys Ser Pro Val Arg Glu Pro Ile Asp Asn 
    130                 135                 140


Leu Thr Pro Glu Glu Arg Asp Ala Arg Thr Val Phe Cys Met Gln Leu 
145                 150                 155                 160


Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe Ser Thr Val 
                165                 170                 175


Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn Ser Arg Arg 
            180                 185                 190


Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser Ser Val Pro 
        195                 200                 205


Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val Pro Ile Ile 
    210                 215                 220


Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala Met Ala Asn 
225                 230                 235                 240


Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr Val Gly Ser 
                245                 250                 255


Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile Phe Glu Pro 
            260                 265                 270


Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser Glu Thr Gly 
        275                 280                 285


Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser Glu Cys Ala 
    290                 295                 300


Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala Gly Arg Pro 
305                 310                 315                 320


Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser Ser Ala Ser 
                325                 330                 335


Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile Asp Leu Gly 
            340                 345                 350


Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu Gly Thr Gly 
        355                 360                 365


Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met Ser Gly Ser 
    370                 375                 380


Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile Asp Leu Gln 
385                 390                 395                 400


Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala Ala Ala Ala 
                405                 410                 415


Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn Met Phe 
            420                 425                 430


Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile Lys Asp 
        435                 440                 445


Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His Ile Tyr 
    450                 455                 460


Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys Pro Ser 
465                 470                 475                 480


Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg Trp Phe 
                485                 490                 495


Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr Tyr His 
            500                 505                 510


Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val Pro Ser 
        515                 520                 525


Arg Arg 
    530


<210>  9879
<211>  3345
<212>  DNA
<213>  Homo sapiens

<400>  9879
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaagagga aaaaaagcaa    600

gagcagaagt cgtagtcatg aacgaaagag aagcaaaagt aaggaacgga agcgaagtag    660

agacagagaa aggaaaaaga gcaaaagccg tgaaagaaag cgaagtagaa gcaaagagag    720

gcgacggagc cgctcaagaa gtcgagatcg aagatttaga ggccgctaca gaagtcctta    780

ctccggacca aaatttaaca gtgccatccg aggaaagatt gggttgcctc atagcatcaa    840

attaagcaga cgacgttccc gaagcaaaag tccattcaga aaagacaaga gccctgtgag    900

agaacctatt gataatttaa ctcctgagga aagagatgca aggacagtct tctgtatgca    960

gctggcggca agaattcgac caagggattt ggaagagttt ttctctacag taggaaaggt   1020

tcgagatgtg aggatgattt ctgacagaaa ttcaagacgt tccaaaggaa ttgcttatgt   1080

ggagttcgtc gatgttagct cagtgcctct agcaatagga ttaactggcc aacgagtttt   1140

aggcgtgcca atcatagtac aggcatcaca ggcagaaaaa aacagagctg cagcaatggc   1200

aaacaattta caaaagggaa gtgctggacc tatgaggctt tatgtgggct cattacactt   1260

caacataact gaagatatgc ttcgtgggat ctttgagcct tttggaagaa ttgaaagtat   1320

ccagctgatg atggacagtg aaactggtcg atccaaggga tatggattta ttacattttc   1380

tgactcagaa tgtgccaaaa aggctttgga acaacttaat ggatttgaac tagcaggaag   1440

accaatgaaa gttggtcatg ttactgaacg tactgatgct tcgagtgcta gttcattttt   1500

ggacagtgat gaactggaaa ggactggaat tgatttggga acaactggtc gtcttcagtt   1560

aatggcaaga cttgcagagg gtacaggttt gcagattccg ccagcagcac agcaagctct   1620

acagatgagt ggctctttgg catttggtgc tgtggcagaa ttctcttttg ttatagattt   1680

gcaaacaaga ctttcccagc agactgaagc ttcagcttta gctgcagctg cctctgttca   1740

gccacttgca acacaatgtt tccaactctc taacatgttt aaccctcaaa cagaagaaga   1800

agttggatgg gataccgaga ttaaggatga tgtgattgaa gaatgtaata aacatggagg   1860

agttattcat atttatgttg acaaaaattc agctcagggc aatgtgtatg tgaagtgccc   1920

atcaattgct gcagctattg ctgctgtcaa tgcattgcat ggcaggtggt ttgctggtaa   1980

aatgataaca gcagcatatg tacctcttcc aacttaccac aacctgtttc ctgattctat   2040

gacagcaaca cagctactgg ttccaagtag acgatgaagg aagatatagt cccttatgta   2100

tatagctttt tttctttctt gagaattcat cttgagttat cttttattta gataaaaata   2160

aagaggcaag gatctactgt catttgtatg caatttcctg ttaccttgaa aaaataaaaa   2220

tgttaacagg aatgcagtgt gctcattctc cctaaatagt aaatcccact gtatacaaaa   2280

ctgttctctt gttctgcctt ttaaaatgtt catgtagaaa attaatgaac tataggaata   2340

gctctaggag aacaaatgtg ctttctgtaa aaaggcagac cagggatgta atgtttttaa   2400

tgtttcagaa gcctaacttt ttacacagtg gttacatttc acatttcact aatgttgata   2460

tttggctgat ggttgagcag tttctgaaat acacatttag tgtatggaaa tacaagacag   2520

ctaaagggct gtttggttag catctcatct tgcattctga tcaattggca agaaagggag   2580

atttcaaaat tatatttctt gatggtatct tttcaattaa tgtatctgta aaagtttctt   2640

tgtaaatact atgtgttctg gtgtgtctta aaattccaaa caaaatgatc cctgcatttc   2700

ctgaagatgt ttaaacgtga gagtctggta ggcaaagcag tctgagaaag aaataggaaa   2760

tgcagaaata ggttttgtct ggttgcatat aatctttgct ctttttaagc tctgtgagct   2820

ctgaaatata tttttgggtt acttcagtgt gtttgacaag acagcttgat atttctatca   2880

aacaaatgac tttcatattg caacaatctt tgtaagaacc actcaaataa aagtctctta   2940

aaaaggccac aggagatctt catttttcaa atgttttaaa gttacagaaa tttgagaaca   3000

gaattagctt cttttagtct caattcagta cttgcctctt gggaaaatgt tccgagtctg   3060

cggaaacttg ccctcacgtt gtcccccatg aattccttta ttctattaga gtctagccct   3120

gtgtatttta gaagaatgta tcaaaactga ggggtttacc aaaaagaaaa ggaaacagcc   3180

tggccttaaa acctgggcat tcttggtctc ctgcattgtc tgggcatatt tatgaagaaa   3240

ttttcaccat ttacaataca tacttaacaa aatggcttaa cttcaaactg gtttccaaaa   3300

ttgatttata tattaatata ttaaataagg tgcatatatt actgt                   3345


<210>  9880
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9880

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9881
<211>  1377
<212>  DNA
<213>  Homo sapiens

<400>  9881
gctgggatta caggcatgag tcaccgcgcc cggcctcatt gaaaatttat ttttcaatac     60

cagactgcag tgttctttgg ggcagagacg ttctgtcaat gtgctttttt tccaaagtat    120

tttttttaat tcatagaata tttaaatttt ttgatacatt tgtaaatata tagtttgtta    180

gtttcaatag tatttaagag tccttaatac tttcttacag agaagaagaa gttggatggg    240

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata    300

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg    360

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag    420

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac    480

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt    540

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg    600

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagga    660

atgcagtgtg ctcattctcc ctaaatagta aatcccactg tatacaaaac tgttctcttg    720

ttctgccttt taaaatgttc atgtagaaaa ttaatgaact ataggaatag ctctaggaga    780

acaaatgtgc tttctgtaaa aaggcagacc agggatgtaa tgtttttaat gtttcagaag    840

cctaactttt tacacagtgg ttacatttca catttcacta atgttgatat ttggctgatg    900

gttgagcagt ttctgaaata cacatttagt gtatggaaat acaagacagc taaagggctg    960

tttggttagc atctcatctt gcattctgat caattggcaa gaaagggaga tttcaaaatt   1020

atatttcttg atggtatctt ttcaattaat gtatctgtaa aagtttcttt gtaaatacta   1080

tgtgttctgg tgtgtcttaa aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt   1140

taaacgtgag agtctggtag gcaaagcagt ctgagaaaga aataggaaat gcagaaatag   1200

gttttgtctg gttgcatata atctttgctc tttttaagct ctgtgagctc tgaaatatat   1260

ttttgggtta cttcagtgtg tttgacaaga cagcttgata tttctatcaa acaaatgact   1320

ttcatattgc aacaatcttt gtaagaacca ctcaaataaa agtctcttaa aaaggcc      1377


<210>  9882
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  9882

Met Asn Tyr Arg Asn Ser Ser Arg Arg Thr Asn Val Leu Ser Val Lys 
1               5                   10                  15


Arg Gln Thr Arg Asp Val Met Phe Leu Met Phe Gln Lys Pro Asn Phe 
            20                  25                  30


Leu His Ser Gly Tyr Ile Ser His Phe Thr Asn Val Asp Ile Trp Leu 
        35                  40                  45


Met Val Glu Gln Phe Leu Lys Tyr Thr Phe Ser Val Trp Lys Tyr Lys 
    50                  55                  60


Thr Ala Lys Gly Leu Phe Gly 
65                  70


<210>  9883
<211>  2006
<212>  DNA
<213>  Homo sapiens

<400>  9883
atgaaatttg gtcagataat atgattacgg tgagttctgt aacagctact ggtaatattt     60

ttgtaaatca cgtgaaagca ttggagcaac tgtcttggaa aatgctcttt aaacttcaaa    120

ccccagtatg ttttggtagt agtggatatt acacatatat gctgctcttt tcagtgttct    180

tttattgtgc gaaaacattt ttaaaacatt tgatttatta ataggattta tttttaatag    240

gattgttaat aggatttatt tttctaggac attgtcttta aacacttgga tgattttata    300

tgtcttaatt ctttaataat ttgtagattt aaaaaacttc gtgggcagaa agcgaagaaa    360

taggaaagga tatagattta tttggcattt caaaggattt tgttttatta tcccctctta    420

tttgggtata aactcaaatc tattttatcc ttcatctgtt tggattgatg tgtattgaga    480

ttttgtctaa ttgaactgat tttgataaca cataaagttt aatttccctg ttaaaatagg    540

actcccaaat ttctgaatgt ctgtttcaag tattaggtta cctcagtttt ctggcaccta    600

aaagctactg ataacataca ttagtagcaa tattaaataa ggtaaaataa ctccagtgac    660

atcctagtta catgcttggg gtgggttttt ggtttcgttt taaagtattt atgagggata    720

ctttcatgca ttttccatga aactaatttt tctctttctt tttttagctt cagctttagc    780

tgcagctgcc tctgttcagc cacttgcaac acaatgtttc caactctcta acatgtttaa    840

ccctcaaaca gaagaagaag ttggatggga taccgagatt aaggatgatg tgattgaaga    900

atgtaataaa catggaggag ttattcatat ttatgttgac aaaaattcag ctcagggcaa    960

tgtgtatgtg aagtgcccat caattgctgc agctattgct gctgtcaatg cattgcatgg   1020

caggtggttt gctggtaaaa tgataacagc agcatatgta cctcttccaa cttaccacaa   1080

cctgtttcct gattctatga cagcaacaca gctactggtt ccaagtagac gatgaaggaa   1140

gatatagtcc cttatgtata tagctttttt tctttcttga gaattcatct tgagttatct   1200

tttatttaga taaaaataaa gaggcaagga tctactgtca tttgtatgca atttcctgtt   1260

accttgaaaa aataaaaatg ttaacaggaa tgcagtgtgc tcattctccc taaatagtaa   1320

atcccactgt atacaaaact gttctcttgt tctgcctttt aaaatgttca tgtagaaaat   1380

taatgaacta taggaatagc tctaggagaa caaatgtgct ttctgtaaaa aggcagacca   1440

gggatgtaat gtttttaatg tttcagaagc ctaacttttt acacagtggt tacatttcac   1500

atttcactaa tgttgatatt tggctgatgg ttgagcagtt tctgaaatac acatttagtg   1560

tatggaaata caagacagct aaagggctgt ttggttagca tctcatcttg cattctgatc   1620

aattggcaag aaagggagat ttcaaaatta tatttcttga tggtatcttt tcaattaatg   1680

tatctgtaaa agtttctttg taaatactat gtgttctggt gtgtcttaaa attccaaaca   1740

aaatgatccc tgcatttcct gaagatgttt aaacgtgaga gtctggtagg caaagcagtc   1800

tgagaaagaa ataggaaatg cagaaatagg ttttgtctgg ttgcatataa tctttgctct   1860

ttttaagctc tgtgagctct gaaatatatt tttgggttac ttcagtgtgt ttgacaagac   1920

agcttgatat ttctatcaaa caaatgactt tcatattgca acaatctttg taagaaccac   1980

tcaaataaaa gtctcttaaa aaggcc                                        2006


<210>  9884
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  9884

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys 
65                  70                  75                  80


Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg 
                85                  90                  95


Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr 
            100                 105                 110


Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val 
        115                 120                 125


Pro Ser Arg Arg 
    130


<210>  9885
<211>  3097
<212>  DNA
<213>  Homo sapiens

<400>  9885
attatgagaa agatatgtca tgttccatca cagtcaagaa ttaaattttt tcacaaacaa     60

gatgcttcta atcagtgctg ttttgttaag agatttttaa aagattttcc tagatttact    120

gtgttctgca ttgatctagc ttgaacgtga atgtttgtat agtacgtttt cttaatattt    180

tttagtattc atagtatata atcatactaa acttgagaaa ctggaagaat caagtcttcc    240

tcagttctgt ttagactttc tagttttttt taaggatact tccatatctt ctgtaagcta    300

cacagtgagc ttcatttttg cacagttata atacactctc gaatctttaa cttttttcca    360

gcagaatttg acatgttata ttaaaatttt gttttattta aaataaaact ttatgaaaga    420

aaaaacttat atgttacaga gaagctaaag cacctgtaat gctaccagaa agttatcatt    480

tatgatatat ttcatgcaca gccctaattt ctcggtgtaa tatttctgat actttaagtg    540

atcgtttatt ttaattacca taatttctaa tgcactgttt tatccttagc tttgtttgtt    600

attatgtttt ggaatgaaat ttggtcagat aatatgatta cggtgagttc tgtaacagct    660

actggtaata tttttgtaaa tcacgtgaaa gcattggagc aactgtcttg gaaaatgctc    720

tttaaacttc aaaccccagt atgttttggt agtagtggat attacacata tatgctgctc    780

ttttcagtgt tcttttattg tgcgaaaaca tttttaaaac atttgattta ttaataggat    840

ttatttttaa taggattgtt aataggattt atttttctag gacattgtct ttaaacactt    900

ggatgatttt atatgtctta attctttaat aatttgtaga tttaaaaaac ttcgtgggca    960

gaaagcgaag aaataggaaa ggatatagat ttatttggca tttcaaagga ttttgtttta   1020

ttatcccctc ttatttgggt ataaactcaa atctatttta tccttcatct gtttggattg   1080

atgtgtattg agattttgtc taattgaact gattttgata acacataaag tttaatttcc   1140

ctgttaaaat aggactccca aatttctgaa tgtctgtttc aagtattagg ttacctcagt   1200

tttctggcac ctaaaagcta ctgataacat acattagtag caatattaaa taaggtaaaa   1260

taactccagt gacatcctag ttacatgctt ggggtgggtt tttggtttcg ttttaaagta   1320

tttatgaggg atactttcat gcattttcca tgaaactaat ttttctcttt ctttttttag   1380

cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct   1440

ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg   1500

atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt   1560

cagctcaggt attttcatct ttttttataa atgatgttag gttgttcgtc tctaccttaa   1620

tcttcgcaca ttatgtggtg catgttatgg ttaaccgtct tccattatag tttttgtgtg   1680

tgtgtgcctg aaagtagctt taatatagtg gctaaataaa ccctccaaaa taaaagaaaa   1740

tcagtaacaa tttgatcagg gtatgagagg atttctagta atgctcaaag cttgccatga   1800

aatcttggca tcttgattca ttcttaggct gcatacaaat cgtagagaaa agataaaacg   1860

gcaaatttga gagtagaagt cattttttaa taaaattcta gtatacctat tagccagtgg   1920

aaccattatg gtaaaccagt ttgtggttat agagcactaa gtttctacag gcaacttgaa   1980

taaacataac ttgggtccat tttgcataca gcaacatctt tacctttttt ttcatttttt   2040

ctgtagggca atgtgtatgt gaagtgccca tcaattgctg cagctattgc tgctgtcaat   2100

gcattgcatg gcaggtggtt tgctggtaaa atgataacag cagcatatgt acctcttcca   2160

acttaccaca acctgtttcc tgattctatg acagcaacac agctactggt tccaagtaga   2220

cgatgaagga agatatagtc ccttatgtat atagcttttt ttctttcttg agaattcatc   2280

ttgagttatc ttttatttag ataaaaataa agaggcaagg atctactgtc atttgtatgc   2340

aatttcctgt taccttgaaa aaataaaaat gttaacagga atgcagtgtg ctcattctcc   2400

ctaaatagta aatcccactg tatacaaaac tgttctcttg ttctgccttt taaaatgttc   2460

atgtagaaaa ttaatgaact ataggaatag ctctaggaga acaaatgtgc tttctgtaaa   2520

aaggcagacc agggatgtaa tgtttttaat gtttcagaag cctaactttt tacacagtgg   2580

ttacatttca catttcacta atgttgatat ttggctgatg gttgagcagt ttctgaaata   2640

cacatttagt gtatggaaat acaagacagc taaagggctg tttggttagc atctcatctt   2700

gcattctgat caattggcaa gaaagggaga tttcaaaatt atatttcttg atggtatctt   2760

ttcaattaat gtatctgtaa aagtttcttt gtaaatacta tgtgttctgg tgtgtcttaa   2820

aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt taaacgtgag agtctggtag   2880

gcaaagcagt ctgagaaaga aataggaaat gcagaaatag gttttgtctg gttgcatata   2940

atctttgctc tttttaagct ctgtgagctc tgaaatatat ttttgggtta cttcagtgtg   3000

tttgacaaga cagcttgata tttctatcaa acaaatgact ttcatattgc aacaatcttt   3060

gtaagaacca ctcaaataaa agtctcttaa aaaggcc                            3097


<210>  9886
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  9886

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Val Phe Ser Ser Phe Phe Ile 
65                  70                  75                  80


Asn Asp Val Arg Leu Phe Val Ser Thr Leu Ile Phe Ala His Tyr Val 
                85                  90                  95


Val His Val Met Val Asn Arg Leu Pro Leu 
            100                 105


<210>  9887
<211>  1549
<212>  DNA
<213>  Homo sapiens

<400>  9887
gggatttaag tgaaccacct cccttggcct cccagagtgc tagctaagtt acaggcgtca     60

accaccacac tcggccctcc ttgcaattta ttttagtgaa gtgatcatga tattaatgac    120

ccaggaaact tcgtttctct gctctcaaca tagtaggaac tttaagacta ttcttttaca    180

ggtacaggtt tgcagattcc gccagcagca cagcaagctc tacagatgag tggctctttg    240

gcatttggtg ctgtggcaga attctctttt gttatagatt tgcaaacaag actttcccag    300

cagactgaag cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt    360

ttccaactct ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag    420

attaaggatg atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt    480

gacaaaaatt cagctcaggg caatgtgtat gtgaagtgcc catcaattgc tgcagctatt    540

gctgctgtca atgcattgca tggcaggtgg tttgctggta aaatgataac agcagcatat    600

gtacctcttc caacttacca caacctgttt cctgattcta tgacagcaac acagctactg    660

gttccaagta gacgatgaag gaagatatag tcccttatgt atatagcttt ttttctttct    720

tgagaattca tcttgagtta tcttttattt agataaaaat aaagaggcaa ggatctactg    780

tcatttgtat gcaatttcct gttaccttga aaaaataaaa atgttaacag gaatgcagtg    840

tgctcattct ccctaaatag taaatcccac tgtatacaaa actgttctct tgttctgcct    900

tttaaaatgt tcatgtagaa aattaatgaa ctataggaat agctctagga gaacaaatgt    960

gctttctgta aaaaggcaga ccagggatgt aatgttttta atgtttcaga agcctaactt   1020

tttacacagt ggttacattt cacatttcac taatgttgat atttggctga tggttgagca   1080

gtttctgaaa tacacattta gtgtatggaa atacaagaca gctaaagggc tgtttggtta   1140

gcatctcatc ttgcattctg atcaattggc aagaaaggga gatttcaaaa ttatatttct   1200

tgatggtatc ttttcaatta atgtatctgt aaaagtttct ttgtaaatac tatgtgttct   1260

ggtgtgtctt aaaattccaa acaaaatgat ccctgcattt cctgaagatg tttaaacgtg   1320

agagtctggt aggcaaagca gtctgagaaa gaaataggaa atgcagaaat aggttttgtc   1380

tggttgcata taatctttgc tctttttaag ctctgtgagc tctgaaatat atttttgggt   1440

tacttcagtg tgtttgacaa gacagcttga tatttctatc aaacaaatga ctttcatatt   1500

gcaacaatct ttgtaagaac cactcaaata aaagtctctt aaaaaggcc               1549


<210>  9888
<211>  150
<212>  PRT
<213>  Homo sapiens

<400>  9888

Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val 
1               5                   10                  15


Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu 
            20                  25                  30


Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu 
        35                  40                  45


Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr 
    50                  55                  60


Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val 
65                  70                  75                  80


Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val 
                85                  90                  95


Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His 
            100                 105                 110


Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu 
        115                 120                 125


Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu 
    130                 135                 140


Leu Val Pro Ser Arg Arg 
145                 150


<210>  9889
<211>  3057
<212>  DNA
<213>  Homo sapiens

<400>  9889
attctattgt aagtttgttt tattaattta ttttgtggat tacagtaatg cttttgttgg     60

cctgttgtat gacaaactat ttaaaggttc acattttgat ttgtatttgc caacaagccc    120

ttttgcttgt taaagctata gctaactctc aggagataat tgcagttcta ctcttagagg    180

atggtgtctt tcaaataatg tcttgtctgc tgattttcag taatgttaat ataaggcaaa    240

agggatattg tttactatac gtagcaattt ttttagacag agtcttactc tgtcgcccag    300

gctggagtac cagtggcggg atcttggctc actgcaacct ccgcttcccg ggtttgagca    360

attctcctgc cttagcctcc cgagtagctg ggactacagg cgcacggtac tatgcccggc    420

taatttttgt atttttatta gggacggggt ttcactacat tggccagact ggtcttgaac    480

tcctgacctt gtgatctgcc tgcctcggcc taccaaagtg ctgagattac aggatttttt    540

ttttttttta agtatgatta tgtaccattg tatcatagta aaactagcca aagaaattta    600

tgaaaggatg aaaaaatgat tctggccata aaaggtagta tattttggtg ggttcttaag    660

ccagcatgat aatggcgagt ttttttcttc tcaggaggaa aaaaagcaag agcagaagtc    720

gtagtcatga acgaaagaga agcaaaagta aggaacggaa gcgaagtaga gacagagaaa    780

ggaaaaagag caaaagccgt gaaagaaagc gaagtagaag caaagagagg cgacggagcc    840

gctcaagaag tcgagatcga agatttagag gccgctacag aagtccttac tccggaccaa    900

aatttaacag tgccatccga ggaaagattg ggttgcctca tagcatcaaa ttaagcagac    960

gacgttcccg aagcaaaagt ccattcagaa aagacaagag ccctgtgaga gaacctattg   1020

ataatttaac tcctgaggaa agagatgcaa ggacagtctt ctgtatgcag ctggcggcaa   1080

gaattcgacc aagggatttg gaagagtttt tctctacagt aggaaaggtt cgagatgtga   1140

ggatgatttc tgacagaaat tcaagacgtt ccaaaggaat tgcttatgtg gagttcgtcg   1200

atgttagctc agtgcctcta gcaataggat taactggcca acgagtttta ggcgtgccaa   1260

tcatagtaca ggcatcacag gcagaaaaaa acagagctgc agcaatggca aacaatttac   1320

aaaagggaag tgctggacct atgaggcttt atgtgggctc attacacttc aacataactg   1380

aagatatgct tcgtgggatc tttgagcctt ttggaagaat tgaaagtatc cagctgatga   1440

tggacagtga aactggtcga tccaagggat atggatttat tacattttct gactcagaat   1500

gtgccaaaaa ggctttggaa caacttaatg gatttgaact agcaggaaga ccaatgaaag   1560

ttggtcatgt tactgaacgt actgatgctt cgagtgctag ttcatttttg gacagtgatg   1620

aactggaaag gactggaatt gatttgggaa caactggtcg tcttcagtta atggcaagac   1680

ttgcagaggg tacaggtttg cagattccgc cagcagcaca gcaagctcta cagatgagtg   1740

gctctttggc atttggtgct gtggcagaat tctcttttgt tatagatttg caaacaagac   1800

tttcccagca gactgaagct tcagctttag ctgcagctgc ctctgttcag ccacttgcaa   1860

cacaatgttt ccaactctct aacatgttta accctcaaac agaagaagaa gttggatggg   1920

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata   1980

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg   2040

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag   2100

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac   2160

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt   2220

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg   2280

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagga   2340

atgcagtgtg ctcattctcc ctaaatagta aatcccactg tatacaaaac tgttctcttg   2400

ttctgccttt taaaatgttc atgtagaaaa ttaatgaact ataggaatag ctctaggaga   2460

acaaatgtgc tttctgtaaa aaggcagacc agggatgtaa tgtttttaat gtttcagaag   2520

cctaactttt tacacagtgg ttacatttca catttcacta atgttgatat ttggctgatg   2580

gttgagcagt ttctgaaata cacatttagt gtatggaaat acaagacagc taaagggctg   2640

tttggttagc atctcatctt gcattctgat caattggcaa gaaagggaga tttcaaaatt   2700

atatttcttg atggtatctt ttcaattaat gtatctgtaa aagtttcttt gtaaatacta   2760

tgtgttctgg tgtgtcttaa aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt   2820

taaacgtgag agtctggtag gcaaagcagt ctgagaaaga aataggaaat gcagaaatag   2880

gttttgtctg gttgcatata atctttgctc tttttaagct ctgtgagctc tgaaatatat   2940

ttttgggtta cttcagtgtg tttgacaaga cagcttgata tttctatcaa acaaatgact   3000

ttcatattgc aacaatcttt gtaagaacca ctcaaataaa agtctcttaa aaaggcc      3057


<210>  9890
<211>  506
<212>  PRT
<213>  Homo sapiens

<400>  9890

Met Ile Met Ala Ser Phe Phe Leu Leu Arg Arg Lys Lys Ser Lys Ser 
1               5                   10                  15


Arg Ser Arg Ser His Glu Arg Lys Arg Ser Lys Ser Lys Glu Arg Lys 
            20                  25                  30


Arg Ser Arg Asp Arg Glu Arg Lys Lys Ser Lys Ser Arg Glu Arg Lys 
        35                  40                  45


Arg Ser Arg Ser Lys Glu Arg Arg Arg Ser Arg Ser Arg Ser Arg Asp 
    50                  55                  60


Arg Arg Phe Arg Gly Arg Tyr Arg Ser Pro Tyr Ser Gly Pro Lys Phe 
65                  70                  75                  80


Asn Ser Ala Ile Arg Gly Lys Ile Gly Leu Pro His Ser Ile Lys Leu 
                85                  90                  95


Ser Arg Arg Arg Ser Arg Ser Lys Ser Pro Phe Arg Lys Asp Lys Ser 
            100                 105                 110


Pro Val Arg Glu Pro Ile Asp Asn Leu Thr Pro Glu Glu Arg Asp Ala 
        115                 120                 125


Arg Thr Val Phe Cys Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp 
    130                 135                 140


Leu Glu Glu Phe Phe Ser Thr Val Gly Lys Val Arg Asp Val Arg Met 
145                 150                 155                 160


Ile Ser Asp Arg Asn Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu 
                165                 170                 175


Phe Val Asp Val Ser Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln 
            180                 185                 190


Arg Val Leu Gly Val Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys 
        195                 200                 205


Asn Arg Ala Ala Ala Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly 
    210                 215                 220


Pro Met Arg Leu Tyr Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp 
225                 230                 235                 240


Met Leu Arg Gly Ile Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln 
                245                 250                 255


Leu Met Met Asp Ser Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile 
            260                 265                 270


Thr Phe Ser Asp Ser Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn 
        275                 280                 285


Gly Phe Glu Leu Ala Gly Arg Pro Met Lys Val Gly His Val Thr Glu 
    290                 295                 300


Arg Thr Asp Ala Ser Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu 
305                 310                 315                 320


Glu Arg Thr Gly Ile Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met 
                325                 330                 335


Ala Arg Leu Ala Glu Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln 
            340                 345                 350


Gln Ala Leu Gln Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu 
        355                 360                 365


Phe Ser Phe Val Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu 
    370                 375                 380


Ala Ser Ala Leu Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln 
385                 390                 395                 400


Cys Phe Gln Leu Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val 
                405                 410                 415


Gly Trp Asp Thr Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys 
            420                 425                 430


His Gly Gly Val Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly 
        435                 440                 445


Asn Val Tyr Val Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val 
    450                 455                 460


Asn Ala Leu His Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala 
465                 470                 475                 480


Tyr Val Pro Leu Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr 
                485                 490                 495


Ala Thr Gln Leu Leu Val Pro Ser Arg Arg 
            500                 505


<210>  9891
<211>  1241
<212>  DNA
<213>  Homo sapiens

<400>  9891
ggtgaatgtg agtacaggga agcagcggcc gccatttcag ggagcttgtc gacgctgtcg     60

caggggtgga tcctgagctg ccgaagccgc cgtcctgctc tcccgcgtgg gcttctctaa    120

ttccattgtt ttttttagat tctctcgggc ctagccgtcc ttggaacccg atattcgggc    180

tgggcggttc cgcggcctgg gcctagggtg cccatcaatt gctgcagcta ttgctgctgt    240

caatgcattg catggcaggt ggtttgctgg taaaatgata acagcagcat atgtacctct    300

tccaacttac cacaacctgt ttcctgattc tatgacagca acacagctac tggttccaag    360

tagacgatga aggaagatat agtcccttat gtatatagct ttttttcttt cttgagaatt    420

catcttgagt tatcttttat ttagataaaa ataaagaggc aaggatctac tgtcatttgt    480

atgcaatttc ctgttacctt gaaaaaataa aaatgttaac aggaatgcag tgtgctcatt    540

ctccctaaat agtaaatccc actgtataca aaactgttct cttgttctgc cttttaaaat    600

gttcatgtag aaaattaatg aactatagga atagctctag gagaacaaat gtgctttctg    660

taaaaaggca gaccagggat gtaatgtttt taatgtttca gaagcctaac tttttacaca    720

gtggttacat ttcacatttc actaatgttg atatttggct gatggttgag cagtttctga    780

aatacacatt tagtgtatgg aaatacaaga cagctaaagg gctgtttggt tagcatctca    840

tcttgcattc tgatcaattg gcaagaaagg gagatttcaa aattatattt cttgatggta    900

tcttttcaat taatgtatct gtaaaagttt ctttgtaaat actatgtgtt ctggtgtgtc    960

ttaaaattcc aaacaaaatg atccctgcat ttcctgaaga tgtttaaacg tgagagtctg   1020

gtaggcaaag cagtctgaga aagaaatagg aaatgcagaa ataggttttg tctggttgca   1080

tataatcttt gctcttttta agctctgtga gctctgaaat atatttttgg gttacttcag   1140

tgtgtttgac aagacagctt gatatttcta tcaaacaaat gactttcata ttgcaacaat   1200

ctttgtaaga accactcaaa taaaagtctc ttaaaaaggc c                       1241


<210>  9892
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  9892

Met Asn Tyr Arg Asn Ser Ser Arg Arg Thr Asn Val Leu Ser Val Lys 
1               5                   10                  15


Arg Gln Thr Arg Asp Val Met Phe Leu Met Phe Gln Lys Pro Asn Phe 
            20                  25                  30


Leu His Ser Gly Tyr Ile Ser His Phe Thr Asn Val Asp Ile Trp Leu 
        35                  40                  45


Met Val Glu Gln Phe Leu Lys Tyr Thr Phe Ser Val Trp Lys Tyr Lys 
    50                  55                  60


Thr Ala Lys Gly Leu Phe Gly 
65                  70


<210>  9893
<211>  2969
<212>  DNA
<213>  Homo sapiens

<400>  9893
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaagacttgc ctaacgatat ctcacctcta    420

ctcccatgaa ttcacctttg attccagtgt gaactgtcaa tcataaggat gagaacaagt    480

tgagcagtgc caacggccat gaagaacgta gcaaaaagag gaaaaaaagc aagagcagaa    540

gtcgtagtca tgaacgaaag agaagcaaaa gtaaggaacg gaagcgaagt agagacagag    600

aaaggaaaaa gagcaaaagc cgtgaaagaa agcgaagtag aagcaaagag aggcgacgga    660

gccgctcaag aagtcgagat cgaagattta gaggccgcta cagaagtcct tactccggac    720

caaaatttaa cagtgccatc cgaggaaaga ttgggttgcc tcatagcatc aaattaagca    780

gacgacgttc ccgaagcaaa agtccattca gaaaagacaa gagccctgtg agagaaccta    840

ttgataattt aactcctgag gaaagagatg caaggacagt cttctgtatg cagctggcgg    900

caagaattcg accaagggat ttggaagagt ttttctctac agtaggaaag gttcgagatg    960

tgaggatgat ttctgacaga aattcaagac gttccaaagg aattgcttat gtggagttcg   1020

tcgatgttag ctcagtgcct ctagcaatag gattaactgg ccaacgagtt ttaggcgtgc   1080

caatcatagt acaggcatca caggcagaaa aaaacagagc tgcagcaatg gcaaacaatt   1140

tacaaaaggg aagtgctgga cctatgaggc tttatgtggg ctcattacac ttcaacataa   1200

ctgaagatat gcttcgtggg atctttgagc cttttggaag aagacagggc tttaccatgt   1260

tggccaagtt ggtctcatac tcctgacctc aggtgatctg cttcggcctc ctaaagtgct   1320

gggattacag attgaaagta tccagctgat gatggacagt gaaactggtc gatccaaggg   1380

atatggattt attacatttt ctgactcaga atgtgccaaa aaggctttgg aacaacttaa   1440

tggatttgaa ctagcaggaa gaccaatgaa agttggtcat gttactgaac gtactgatgc   1500

ttcgagtgct agttcatttt tggacagtga tgaactggaa aggactggaa ttgatttggg   1560

aacaactggt cgtcttcagt taatggcaag acttgcagag ggtacaggtt tgcagattcc   1620

gccagcagca cagcaagctc tacagatgag tggctctttg gcatttggtg ctgtggcaga   1680

attctctttt gttatagatt tgcaaacaag actttcccag cagactgaag cttcagcttt   1740

agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct ctaacatgtt   1800

taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg atgtgattga   1860

agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt cagctcaggg   1920

caatgtgtat gtgaagtgcc catcaattgc tgcagctatt gctgctgtca atgcattgca   1980

tggcaggtgg tttgctggta aaatgataac agcagcatat gtacctcttc caacttacca   2040

caacctgttt cctgattcta tgacagcaac acagctactg gttccaagta gacgatgaag   2100

gaagatatag tcccttatgt atatagcttt ttttctttct tgagaattca tcttgagtta   2160

tcttttattt agataaaaat aaagaggcaa ggatctactg tcatttgtat gcaatttcct   2220

gttaccttga aaaaataaaa atgttaacag gaatgcagtg tgctcattct ccctaaatag   2280

taaatcccac tgtatacaaa actgttctct tgttctgcct tttaaaatgt tcatgtagaa   2340

aattaatgaa ctataggaat agctctagga gaacaaatgt gctttctgta aaaaggcaga   2400

ccagggatgt aatgttttta atgtttcaga agcctaactt tttacacagt ggttacattt   2460

cacatttcac taatgttgat atttggctga tggttgagca gtttctgaaa tacacattta   2520

gtgtatggaa atacaagaca gctaaagggc tgtttggtta gcatctcatc ttgcattctg   2580

atcaattggc aagaaaggga gatttcaaaa ttatatttct tgatggtatc ttttcaatta   2640

atgtatctgt aaaagtttct ttgtaaatac tatgtgttct ggtgtgtctt aaaattccaa   2700

acaaaatgat ccctgcattt cctgaagatg tttaaacgtg agagtctggt aggcaaagca   2760

gtctgagaaa gaaataggaa atgcagaaat aggttttgtc tggttgcata taatctttgc   2820

tctttttaag ctctgtgagc tctgaaatat atttttgggt tacttcagtg tgtttgacaa   2880

gacagcttga tatttctatc aaacaaatga ctttcatatt gcaacaatct ttgtaagaac   2940

cactcaaata aaagtctctt aaaaaggcc                                     2969


<210>  9894
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  9894

Met Met Asp Ser Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr 
1               5                   10                  15


Phe Ser Asp Ser Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly 
            20                  25                  30


Phe Glu Leu Ala Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg 
        35                  40                  45


Thr Asp Ala Ser Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu 
    50                  55                  60


Arg Thr Gly Ile Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala 
65                  70                  75                  80


Arg Leu Ala Glu Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln 
                85                  90                  95


Ala Leu Gln Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe 
            100                 105                 110


Ser Phe Val Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala 
        115                 120                 125


Ser Ala Leu Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys 
    130                 135                 140


Phe Gln Leu Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly 
145                 150                 155                 160


Trp Asp Thr Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His 
                165                 170                 175


Gly Gly Val Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn 
            180                 185                 190


Val Tyr Val Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn 
        195                 200                 205


Ala Leu His Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr 
    210                 215                 220


Val Pro Leu Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala 
225                 230                 235                 240


Thr Gln Leu Leu Val Pro Ser Arg Arg 
                245


<210>  9895
<211>  2849
<212>  DNA
<213>  Homo sapiens

<400>  9895
gcgagagccc gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc     60

tggtgaatgt gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc    120

gcaggggtgg atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta    180

attccattgt tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg    240

ctgggcggtt ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc    300

ggcagcagca gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga    360

aggccggaac aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga    420

ggctccttac aagaaggatg agaacaagtt gagcagtgcc aacggccatg aagaacgtag    480

caaaaagagg aaaaaaagca agagcagaag tcgtagtcat gaacgaaaga gaagcaaaag    540

taaggaacgg aagcgaagta gagacagaga aaggaaaaag agcaaaagcc gtgaaagaaa    600

gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga agtcgagatc gaagatttag    660

aggccgctac agaagtcctt actccggacc aaaatttaac agtgccatcc gaggaaagat    720

tgggttgcct catagcatca aattaagcag acgacgttcc cgaagcaaaa gtccattcag    780

aaaagacaag agccctgtga gagaacctat tgataattta actcctgagg aaagagatgc    840

aaggacagtc ttctgtatgc agctggcggc aagaattcga ccaagggatt tggaagagtt    900

tttctctaca gtaggaaagg ttcgagatgt gaggatgatt tctgacagaa attcaagacg    960

ttccaaagga attgcttatg tggagttcgt cgatgttagc tcagtgcctc tagcaatagg   1020

attaactggc caacgagttt taggcgtgcc aatcatagta caggcatcac aggcagaaaa   1080

aaacagagct gcagcaatgg caaacaattt acaaaaggga agtgctggac ctatgaggct   1140

ttatgtgggc tcattacact tcaacataac tgaagatatg cttcgtggga tctttgagcc   1200

ttttggaaga attgaaagta tccagctgat gatggacagt gaaactggtc gatccaaggg   1260

atatggattt attacatttt ctgactcaga atgtgccaaa aaggctttgg aacaacttaa   1320

tggatttgaa ctagcaggaa gaccaatgaa agttggtcat gttactgaac gtactgatgc   1380

ttcgagtgct agttcatttt tggacagtga tgaactggaa aggactggaa ttgatttggg   1440

aacaactggt cgtcttcagt taatggcaag acttgcagag ggtacaggtt tgcagattcc   1500

gccagcagca cagcaagctc tacagatgag tggctctttg gcatttggtg ctgtggcaga   1560

attctctttt gttatagatt tgcaaacaag actttcccag cagactgaag cttcagcttt   1620

agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct ctaacatgtt   1680

taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg atgtgattga   1740

agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt cagctcaggg   1800

caatgtgtat gtgaagtgcc catcaattgc tgcagctatt gctgctgtca atgcattgca   1860

tggcaggtgg tttgctggta aaatgataac agcagcatat gtacctcttc caacttacca   1920

caacctgttt cctgattcta tgacagcaac acagctactg gttccaagta gacgatgaag   1980

gaagatatag tcccttatgt atatagcttt ttttctttct tgagaattca tcttgagtta   2040

tcttttattt agataaaaat aaagaggcaa ggatctactg tcatttgtat gcaatttcct   2100

gttaccttga aaaaataaaa atgttaacag gaatgcagtg tgctcattct ccctaaatag   2160

taaatcccac tgtatacaaa actgttctct tgttctgcct tttaaaatgt tcatgtagaa   2220

aattaatgaa ctataggaat agctctagga gaacaaatgt gctttctgta aaaaggcaga   2280

ccagggatgt aatgttttta atgtttcaga agcctaactt tttacacagt ggttacattt   2340

cacatttcac taatgttgat atttggctga tggttgagca gtttctgaaa tacacattta   2400

gtgtatggaa atacaagaca gctaaagggc tgtttggtta gcatctcatc ttgcattctg   2460

atcaattggc aagaaaggga gatttcaaaa ttatatttct tgatggtatc ttttcaatta   2520

atgtatctgt aaaagtttct ttgtaaatac tatgtgttct ggtgtgtctt aaaattccaa   2580

acaaaatgat ccctgcattt cctgaagatg tttaaacgtg agagtctggt aggcaaagca   2640

gtctgagaaa gaaataggaa atgcagaaat aggttttgtc tggttgcata taatctttgc   2700

tctttttaag ctctgtgagc tctgaaatat atttttgggt tacttcagtg tgtttgacaa   2760

gacagcttga tatttctatc aaacaaatga ctttcatatt gcaacaatct ttgtaagaac   2820

cactcaaata aaagtctctt aaaaaggcc                                     2849


<210>  9896
<211>  530
<212>  PRT
<213>  Homo sapiens

<400>  9896

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Arg Lys Lys Ser Lys Ser Arg Ser Arg Ser His Glu Arg Lys 
        35                  40                  45


Arg Ser Lys Ser Lys Glu Arg Lys Arg Ser Arg Asp Arg Glu Arg Lys 
    50                  55                  60


Lys Ser Lys Ser Arg Glu Arg Lys Arg Ser Arg Ser Lys Glu Arg Arg 
65                  70                  75                  80


Arg Ser Arg Ser Arg Ser Arg Asp Arg Arg Phe Arg Gly Arg Tyr Arg 
                85                  90                  95


Ser Pro Tyr Ser Gly Pro Lys Phe Asn Ser Ala Ile Arg Gly Lys Ile 
            100                 105                 110


Gly Leu Pro His Ser Ile Lys Leu Ser Arg Arg Arg Ser Arg Ser Lys 
        115                 120                 125


Ser Pro Phe Arg Lys Asp Lys Ser Pro Val Arg Glu Pro Ile Asp Asn 
    130                 135                 140


Leu Thr Pro Glu Glu Arg Asp Ala Arg Thr Val Phe Cys Met Gln Leu 
145                 150                 155                 160


Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe Ser Thr Val 
                165                 170                 175


Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn Ser Arg Arg 
            180                 185                 190


Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser Ser Val Pro 
        195                 200                 205


Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val Pro Ile Ile 
    210                 215                 220


Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala Met Ala Asn 
225                 230                 235                 240


Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr Val Gly Ser 
                245                 250                 255


Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile Phe Glu Pro 
            260                 265                 270


Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser Glu Thr Gly 
        275                 280                 285


Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser Glu Cys Ala 
    290                 295                 300


Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala Gly Arg Pro 
305                 310                 315                 320


Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser Ser Ala Ser 
                325                 330                 335


Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile Asp Leu Gly 
            340                 345                 350


Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu Gly Thr Gly 
        355                 360                 365


Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met Ser Gly Ser 
    370                 375                 380


Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile Asp Leu Gln 
385                 390                 395                 400


Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala Ala Ala Ala 
                405                 410                 415


Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn Met Phe 
            420                 425                 430


Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile Lys Asp 
        435                 440                 445


Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His Ile Tyr 
    450                 455                 460


Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys Pro Ser 
465                 470                 475                 480


Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg Trp Phe 
                485                 490                 495


Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr Tyr His 
            500                 505                 510


Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val Pro Ser 
        515                 520                 525


Arg Arg 
    530


<210>  9897
<211>  2902
<212>  DNA
<213>  Homo sapiens

<400>  9897
gcgagagccc gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc     60

tggtgaatgt gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc    120

gcaggggtgg atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta    180

attccattgt tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg    240

ctgggcggtt ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc    300

ggcagcagca gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga    360

aggccggaac aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga    420

ggctccttac aagaaggatg agaacaagtt gagcagtgcc aacggccatg aagaacgtag    480

caaaaagagg aaaaaaagca agagcagaag tcgtagtcat gaacgaaaga gaagcaaaag    540

taaggaacgg aagcgaagta gagacagaga aaggaaaaag agcaaaagcc gtgaaagaaa    600

gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga agtcgagatc gaagatttag    660

aggccgctac agaagtcctt actccggacc aaaatttaac agtgccatcc gaggaaagat    720

tgggttgcct catagcatca aattaagcag acgacgttcc cgaagcaaaa gtccattcag    780

aaaagacaag agccctgtga gagaacctat tgataattta actcctgagg aaagagatgc    840

aaggacagtc ttctgtatgc agctggcggc aagaattcga ccaagggatt tggaagagtt    900

tttctctaca gtaggaaagg ttcgagatgt gaggatgatt tctgacagaa attcaagacg    960

ttccaaagga attgcttatg tggagttcgt cgatgttagc tcagtgcctc tagcaatagg   1020

attaactggc caacgagttt taggcgtgcc aatcatagta caggcatcac aggcagaaaa   1080

aaacagagct gcagcaatgg caaacaattt acaaaaggga agtgctggac ctatgaggct   1140

ttatgtgggc tcattacact tcaacataac tgaagatatg cttcgtggga tctttgagcc   1200

ttttggaaga attgaaagta tccagctgat gatggacagt gaaactggtc gatccaaggg   1260

atatggattt attacatttt ctgactcaga atgtgccaaa aaggctttgg aacaacttaa   1320

tggatttgaa ctagcaggaa gaccaatgaa agttggtcat gttactgaac gtactgatgc   1380

ttcgagtgct agttcatttt tggacagtga tgaactggaa aggactggaa ttgatttggg   1440

aacaactggt cgtcttcagt taatggcaag acttgcagag ggtacaggtt tgcagattcc   1500

gccagcagca cagcaagctc tacagatgag tggctctttg gcatttggtg ctgtggcaga   1560

attctctttt gttatagatt tgcaaacaag actttcccag cagactgaag ctttgtttgt   1620

tattatgttt tggaatgaaa tttggtcaga taatatgatt acgcttcagc tttagctgca   1680

gctgcctctg ttcagccact tgcaacacaa tgtttccaac tctctaacat gtttaaccct   1740

caaacagaag aagaagttgg atgggatacc gagattaagg atgatgtgat tgaagaatgt   1800

aataaacatg gaggagttat tcatatttat gttgacaaaa attcagctca gggcaatgtg   1860

tatgtgaagt gcccatcaat tgctgcagct attgctgctg tcaatgcatt gcatggcagg   1920

tggtttgctg gtaaaatgat aacagcagca tatgtacctc ttccaactta ccacaacctg   1980

tttcctgatt ctatgacagc aacacagcta ctggttccaa gtagacgatg aaggaagata   2040

tagtccctta tgtatatagc tttttttctt tcttgagaat tcatcttgag ttatctttta   2100

tttagataaa aataaagagg caaggatcta ctgtcatttg tatgcaattt cctgttacct   2160

tgaaaaaata aaaatgttaa caggaatgca gtgtgctcat tctccctaaa tagtaaatcc   2220

cactgtatac aaaactgttc tcttgttctg ccttttaaaa tgttcatgta gaaaattaat   2280

gaactatagg aatagctcta ggagaacaaa tgtgctttct gtaaaaaggc agaccaggga   2340

tgtaatgttt ttaatgtttc agaagcctaa ctttttacac agtggttaca tttcacattt   2400

cactaatgtt gatatttggc tgatggttga gcagtttctg aaatacacat ttagtgtatg   2460

gaaatacaag acagctaaag ggctgtttgg ttagcatctc atcttgcatt ctgatcaatt   2520

ggcaagaaag ggagatttca aaattatatt tcttgatggt atcttttcaa ttaatgtatc   2580

tgtaaaagtt tctttgtaaa tactatgtgt tctggtgtgt cttaaaattc caaacaaaat   2640

gatccctgca tttcctgaag atgtttaaac gtgagagtct ggtaggcaaa gcagtctgag   2700

aaagaaatag gaaatgcaga aataggtttt gtctggttgc atataatctt tgctcttttt   2760

aagctctgtg agctctgaaa tatatttttg ggttacttca gtgtgtttga caagacagct   2820

tgatatttct atcaaacaaa tgactttcat attgcaacaa tctttgtaag aaccactcaa   2880

ataaaagtct cttaaaaagg cc                                            2902


<210>  9898
<211>  429
<212>  PRT
<213>  Homo sapiens

<400>  9898

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Arg Lys Lys Ser Lys Ser Arg Ser Arg Ser His Glu Arg Lys 
        35                  40                  45


Arg Ser Lys Ser Lys Glu Arg Lys Arg Ser Arg Asp Arg Glu Arg Lys 
    50                  55                  60


Lys Ser Lys Ser Arg Glu Arg Lys Arg Ser Arg Ser Lys Glu Arg Arg 
65                  70                  75                  80


Arg Ser Arg Ser Arg Ser Arg Asp Arg Arg Phe Arg Gly Arg Tyr Arg 
                85                  90                  95


Ser Pro Tyr Ser Gly Pro Lys Phe Asn Ser Ala Ile Arg Gly Lys Ile 
            100                 105                 110


Gly Leu Pro His Ser Ile Lys Leu Ser Arg Arg Arg Ser Arg Ser Lys 
        115                 120                 125


Ser Pro Phe Arg Lys Asp Lys Ser Pro Val Arg Glu Pro Ile Asp Asn 
    130                 135                 140


Leu Thr Pro Glu Glu Arg Asp Ala Arg Thr Val Phe Cys Met Gln Leu 
145                 150                 155                 160


Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe Ser Thr Val 
                165                 170                 175


Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn Ser Arg Arg 
            180                 185                 190


Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser Ser Val Pro 
        195                 200                 205


Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val Pro Ile Ile 
    210                 215                 220


Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala Met Ala Asn 
225                 230                 235                 240


Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr Val Gly Ser 
                245                 250                 255


Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile Phe Glu Pro 
            260                 265                 270


Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser Glu Thr Gly 
        275                 280                 285


Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser Glu Cys Ala 
    290                 295                 300


Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala Gly Arg Pro 
305                 310                 315                 320


Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser Ser Ala Ser 
                325                 330                 335


Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile Asp Leu Gly 
            340                 345                 350


Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu Gly Thr Gly 
        355                 360                 365


Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met Ser Gly Ser 
    370                 375                 380


Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile Asp Leu Gln 
385                 390                 395                 400


Thr Arg Leu Ser Gln Gln Thr Glu Ala Leu Phe Val Ile Met Phe Trp 
                405                 410                 415


Asn Glu Ile Trp Ser Asp Asn Met Ile Thr Leu Gln Leu 
            420                 425


<210>  9899
<211>  2948
<212>  DNA
<213>  Homo sapiens

<400>  9899
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaagagga aaaaaagcaa    600

gagcagaagt cgtagtcatg aacgaaagag aagcaaaagt aaggaacgga agcgaagtag    660

agacagagaa aggaaaaaga gcaaaagccg tgaaagaaag cgaagtagaa gcaaagagag    720

gcgacggagc cgctcaagaa gtcgagatcg aagatttaga ggccgctaca gaagtcctta    780

ctccggacca aaatttaaca gtgccatccg aggaaagatt gggttgcctc atagcatcaa    840

attaagcaga cgacgttccc gaagcaaaag tccattcaga aaagacaaga gccctgtgag    900

agaacctatt gataatttaa ctcctgagga aagagatgca aggacagtct tctgtatgca    960

gctggcggca agaattcgac caagggattt ggaagagttt ttctctacag taggaaaggt   1020

tcgagatgtg aggatgattt ctgacagaaa ttcaagacgt tccaaaggaa ttgcttatgt   1080

ggagttcgtc gatgttagct cagtgcctct agcaatagga ttaactggcc aacgagtttt   1140

aggcgtgcca atcatagtac aggcatcaca ggcagaaaaa aacagagctg cagcaatggc   1200

aaacaattta caaaagggaa gtgctggacc tatgaggctt tatgtgggct cattacactt   1260

caacataact gaagatatgc ttcgtgggat ctttgagcct tttggaagaa ttgaaagtat   1320

ccagctgatg atggacagtg aaactggtcg atccaaggga tatggattta ttacattttc   1380

tgactcagaa tgtgccaaaa aggctttgga acaacttaat ggatttgaac tagcaggaag   1440

accaatgaaa gttggtcatg ttactgaacg tactgatgct tcgagtgcta gttcattttt   1500

ggacagtgat gaactggaaa ggactggaat tgatttggga acaactggtc gtcttcagtt   1560

aatggcaaga cttgcagagg gtacaggttt gcagattccg ccagcagcac agcaagctct   1620

acagatgagt ggctctttgg catttggtgc tgtggcagaa ttctcttttg ttatagattt   1680

gcaaacaaga ctttcccagc agactgaagc ttcagcttta gctgcagctg cctctgttca   1740

gccacttgca acacaatgtt tccaactctc taacatgttt aaccctcaaa cagaagaaga   1800

agttggatgg gataccgaga ttaaggatga tgtgattgaa gaatgtaata aacatggagg   1860

agttattcat atttatgttg acaaaaattc agctcagggc aatgtgtatg tgaagtgccc   1920

atcaattgct gcagctattg ctgctgtcaa tgcattgcat ggcaggtggt ttgctggtaa   1980

aatgataaca gcagcatatg tacctcttcc aacttaccac aacctgtttc ctgattctat   2040

gacagcaaca cagctactgg ttccaagtag acgatgaagg aagatatagt cccttatgta   2100

tatagctttt tttctttctt gagaattcat cttgagttat cttttattta gataaaaata   2160

aagaggcaag gatctactgt catttgtatg caatttcctg ttaccttgaa aaaataaaaa   2220

tgttaacagg aatgcagtgt gctcattctc cctaaatagt aaatcccact gtatacaaaa   2280

ctgttctctt gttctgcctt ttaaaatgtt catgtagaaa attaatgaac tataggaata   2340

gctctaggag aacaaatgtg ctttctgtaa aaaggcagac cagggatgta atgtttttaa   2400

tgtttcagaa gcctaacttt ttacacagtg gttacatttc acatttcact aatgttgata   2460

tttggctgat ggttgagcag tttctgaaat acacatttag tgtatggaaa tacaagacag   2520

ctaaagggct gtttggttag catctcatct tgcattctga tcaattggca agaaagggag   2580

atttcaaaat tatatttctt gatggtatct tttcaattaa tgtatctgta aaagtttctt   2640

tgtaaatact atgtgttctg gtgtgtctta aaattccaaa caaaatgatc cctgcatttc   2700

ctgaagatgt ttaaacgtga gagtctggta ggcaaagcag tctgagaaag aaataggaaa   2760

tgcagaaata ggttttgtct ggttgcatat aatctttgct ctttttaagc tctgtgagct   2820

ctgaaatata tttttgggtt acttcagtgt gtttgacaag acagcttgat atttctatca   2880

aacaaatgac tttcatattg caacaatctt tgtaagaacc actcaaataa aagtctctta   2940

aaaaggcc                                                            2948


<210>  9900
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9900

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9901
<211>  4681
<212>  DNA
<213>  Homo sapiens

<400>  9901
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga aggtgagaaa aaacatgtcg    480

gtgaggttta tatatttctt aatttagcat tattcacgaa actactgctg aaatgtaaac    540

taacctcccc ggagccctct tgatttatct tatcagagat gcattacgtg taacttacaa    600

aagtaaatat atgctattga tgtaataata ttgtgcagta gtttcacttc agcgtgatga    660

ataaatgccc atctatctct ctttgtagac ttgcctaacg atatctcacc tctactccca    720

tgaattcacc tttgattcca gtgtgaactg tcaatcataa ggtagtaatt gagtgactta    780

tcgctgtacc gtggtcccct aggtaaaatg actcaactaa gaattaccac ctccagtttg    840

gtatagcaaa aaggtgaatg tagtggtttg ggaaaaagca ggggtccaag aataacaaag    900

catgaccagt ctgtggcaag ttaaatcttc taacagtctt ataagaagaa atgggtgaga    960

ttttaaaatt tatgtatcta tgtaagactg gtgatagtaa atcttaaaac agtccagtgg   1020

caatctgctg ctcagttaat aattactaaa attcttggat ccctgaatag aaattaaaaa   1080

aaaaaaatac aagaggcagt agagtcaata caagcttaat acaagcttag agtaaataca   1140

agcttagagt cacttgatga ctgttttact gttctccata ttgtttttat ttttaattag   1200

gccctaccat agtatttcac actaaaaaca aaggaattat attggctaat atagtctttg   1260

actcatttcg gtatctcagt aaaagtaaac tgtcttttca ttgtttcacc agttggtggt   1320

gaaaatagca gtatgcatgc attatcactg gtgtcacaaa ctgtaagctt tgtaagttag   1380

cactttactc ctatagctga tgtaatcaaa ctttaaaata aacatttcac taaacctttt   1440

aaaaataata catttgtttt ggattgtata gcacgaccat gtggtaccaa tttggatgaa   1500

ttcttgatag atttaaatag tgtatgtaat tttgtaatgc ttagactctt gaagagctac   1560

tttctgtttt aatgttaaga ttcttgtgtc ttagtttttt ttaacatgga tgtaattcca   1620

tgtaaacagg tatggaagta ggaaatgttt aggctggact tggtggatta ttaattgact   1680

ttcttgggtt cttgggagtc aacattacta aagcagtgtg aatccctgtt tgcttcaggg   1740

cgagatgtgt gacagaggtg gcatcaagct cttacagtcc caaccctcca acggaaatgg   1800

gcgaagatct caggaatggc atcggtcaca ggaaatcgat agtggctggc tgctagcatg   1860

gccacttggg gcttaggcag aaatagagcc atggtactga ccaaagggac catagcacat   1920

ggaataaaac tcaaaacagg acttcatgtt ttatggaaat tatatttaac cacttcaaca   1980

ttgtaaatct ggataacttt taatatctaa actatataag aaagtaaaat ttaacatgtt   2040

aatatggaaa atttttttat ttttgtatct tgatgactta aatgtaagca acaaagtggt   2100

taaacacata cccatctaaa tttttttata gccttccatg ttaaactata agtaaataat   2160

tagttttaaa attgttttgt attttcttat tcctgttccc tttacccttt gacaacttga   2220

aatgttacca cttcgtcctc atgatgttct tctatcaacc ctgcttagga tgagaacaag   2280

ttgagcagtg ccaacggcca tgaagaacgt agcaaaaaga ggaaaaaaag caagagcaga   2340

agtcgtagtc atgaacgaaa gagaagcaaa agtaaggaac ggaagcgaag tagagacaga   2400

gaaaggaaaa agagcaaaag ccgtgaaaga aagcgaagta gaagcaaaga gaggcgacgg   2460

agccgctcaa gaagtcgaga tcgaagattt agaggccgct acagaagtcc ttactccgga   2520

ccaaaattta acagtgccat ccgaggaaag attgggttgc ctcatagcat caaattaagc   2580

agacgacgtt cccgaagcaa aagtccattc agaaaagaca agagccctgt gagagaacct   2640

attgataatt taactcctga ggaaagagat gcaaggacag tcttctgtat gcagctggcg   2700

gcaagaattc gaccaaggga tttggaagag tttttctcta cagtaggaaa ggttcgagat   2760

gtgaggatga tttctgacag aaattcaaga cgttccaaag gaattgctta tgtggagttc   2820

gtcgatgtta gctcagtgcc tctagcaata ggattaactg gccaacgagt tttaggcgtg   2880

ccaatcatag tacaggcatc acaggcagaa aaaaacagag ctgcagcaat ggcaaacaat   2940

ttacaaaagg gaagtgctgg acctatgagg ctttatgtgg gctcattaca cttcaacata   3000

actgaagata tgcttcgtgg gatctttgag ccttttggaa gaattgaaag tatccagctg   3060

atgatggaca gtgaaactgg tcgatccaag ggatatggat ttattacatt ttctgactca   3120

gaatgtgcca aaaaggcttt ggaacaactt aatggatttg aactagcagg aagaccaatg   3180

aaagttggtc atgttactga acgtactgat gcttcgagtg ctagttcatt tttggacagt   3240

gatgaactgg aaaggactgg aattgatttg ggaacaactg gtcgtcttca gttaatggca   3300

agacttgcag agggtacagg tttgcagatt ccgccagcag cacagcaagc tctacagatg   3360

agtggctctt tggcatttgg tgctgtggca gaattctctt ttgttataga tttgcaaaca   3420

agactttccc agcagactga agcttcagct ttagctgcag ctgcctctgt tcagccactt   3480

gcaacacaat gtttccaact ctctaacatg tttaaccctc aaacagaaga agaagttgga   3540

tgggataccg agattaagga tgatgtgatt gaagaatgta ataaacatgg aggagttatt   3600

catatttatg ttgacaaaaa ttcagctcag ggcaatgtgt atgtgaagtg cccatcaatt   3660

gctgcagcta ttgctgctgt caatgcattg catggcaggt ggtttgctgg taaaatgata   3720

acagcagcat atgtacctct tccaacttac cacaacctgt ttcctgattc tatgacagca   3780

acacagctac tggttccaag tagacgatga aggaagatat agtcccttat gtatatagct   3840

ttttttcttt cttgagaatt catcttgagt tatcttttat ttagataaaa ataaagaggc   3900

aaggatctac tgtcatttgt atgcaatttc ctgttacctt gaaaaaataa aaatgttaac   3960

aggaatgcag tgtgctcatt ctccctaaat agtaaatccc actgtataca aaactgttct   4020

cttgttctgc cttttaaaat gttcatgtag aaaattaatg aactatagga atagctctag   4080

gagaacaaat gtgctttctg taaaaaggca gaccagggat gtaatgtttt taatgtttca   4140

gaagcctaac tttttacaca gtggttacat ttcacatttc actaatgttg atatttggct   4200

gatggttgag cagtttctga aatacacatt tagtgtatgg aaatacaaga cagctaaagg   4260

gctgtttggt tagcatctca tcttgcattc tgatcaattg gcaagaaagg gagatttcaa   4320

aattatattt cttgatggta tcttttcaat taatgtatct gtaaaagttt ctttgtaaat   4380

actatgtgtt ctggtgtgtc ttaaaattcc aaacaaaatg atccctgcat ttcctgaaga   4440

tgtttaaacg tgagagtctg gtaggcaaag cagtctgaga aagaaatagg aaatgcagaa   4500

ataggttttg tctggttgca tataatcttt gctcttttta agctctgtga gctctgaaat   4560

atatttttgg gttacttcag tgtgtttgac aagacagctt gatatttcta tcaaacaaat   4620

gactttcata ttgcaacaat ctttgtaaga accactcaaa taaaagtctc ttaaaaaggc   4680

c                                                                   4681


<210>  9902
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9902

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9903
<211>  659
<212>  DNA
<213>  Homo sapiens

<400>  9903
gctgggatta caggcatgag tcaccgcgcc cggcctcatt gaaaatttat ttttcaatac     60

cagactgcag tgttctttgg ggcagagacg ttctgtcaat gtgctttttt tccaaagtat    120

tttttttaat tcatagaata tttaaatttt ttgatacatt tgtaaatata tagtttgtta    180

gtttcaatag tatttaagag tccttaatac tttcttacag agaagaagaa gttggatggg    240

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata    300

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg    360

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag    420

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac    480

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt    540

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg    600

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagg     659


<210>  9904
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9904

Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr Tyr His Asn Leu Phe 
1               5                   10                  15


Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val Pro Ser Arg Arg 
            20                  25                  30


<210>  9905
<211>  1288
<212>  DNA
<213>  Homo sapiens

<400>  9905
atgaaatttg gtcagataat atgattacgg tgagttctgt aacagctact ggtaatattt     60

ttgtaaatca cgtgaaagca ttggagcaac tgtcttggaa aatgctcttt aaacttcaaa    120

ccccagtatg ttttggtagt agtggatatt acacatatat gctgctcttt tcagtgttct    180

tttattgtgc gaaaacattt ttaaaacatt tgatttatta ataggattta tttttaatag    240

gattgttaat aggatttatt tttctaggac attgtcttta aacacttgga tgattttata    300

tgtcttaatt ctttaataat ttgtagattt aaaaaacttc gtgggcagaa agcgaagaaa    360

taggaaagga tatagattta tttggcattt caaaggattt tgttttatta tcccctctta    420

tttgggtata aactcaaatc tattttatcc ttcatctgtt tggattgatg tgtattgaga    480

ttttgtctaa ttgaactgat tttgataaca cataaagttt aatttccctg ttaaaatagg    540

actcccaaat ttctgaatgt ctgtttcaag tattaggtta cctcagtttt ctggcaccta    600

aaagctactg ataacataca ttagtagcaa tattaaataa ggtaaaataa ctccagtgac    660

atcctagtta catgcttggg gtgggttttt ggtttcgttt taaagtattt atgagggata    720

ctttcatgca ttttccatga aactaatttt tctctttctt tttttagctt cagctttagc    780

tgcagctgcc tctgttcagc cacttgcaac acaatgtttc caactctcta acatgtttaa    840

ccctcaaaca gaagaagaag ttggatggga taccgagatt aaggatgatg tgattgaaga    900

atgtaataaa catggaggag ttattcatat ttatgttgac aaaaattcag ctcagggcaa    960

tgtgtatgtg aagtgcccat caattgctgc agctattgct gctgtcaatg cattgcatgg   1020

caggtggttt gctggtaaaa tgataacagc agcatatgta cctcttccaa cttaccacaa   1080

cctgtttcct gattctatga cagcaacaca gctactggtt ccaagtagac gatgaaggaa   1140

gatatagtcc cttatgtata tagctttttt tctttcttga gaattcatct tgagttatct   1200

tttatttaga taaaaataaa gaggcaagga tctactgtca tttgtatgca atttcctgtt   1260

accttgaaaa aataaaaatg ttaacagg                                      1288


<210>  9906
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  9906

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys 
65                  70                  75                  80


Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg 
                85                  90                  95


Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr 
            100                 105                 110


Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val 
        115                 120                 125


Pro Ser Arg Arg 
    130


<210>  9907
<211>  2379
<212>  DNA
<213>  Homo sapiens

<400>  9907
attatgagaa agatatgtca tgttccatca cagtcaagaa ttaaattttt tcacaaacaa     60

gatgcttcta atcagtgctg ttttgttaag agatttttaa aagattttcc tagatttact    120

gtgttctgca ttgatctagc ttgaacgtga atgtttgtat agtacgtttt cttaatattt    180

tttagtattc atagtatata atcatactaa acttgagaaa ctggaagaat caagtcttcc    240

tcagttctgt ttagactttc tagttttttt taaggatact tccatatctt ctgtaagcta    300

cacagtgagc ttcatttttg cacagttata atacactctc gaatctttaa cttttttcca    360

gcagaatttg acatgttata ttaaaatttt gttttattta aaataaaact ttatgaaaga    420

aaaaacttat atgttacaga gaagctaaag cacctgtaat gctaccagaa agttatcatt    480

tatgatatat ttcatgcaca gccctaattt ctcggtgtaa tatttctgat actttaagtg    540

atcgtttatt ttaattacca taatttctaa tgcactgttt tatccttagc tttgtttgtt    600

attatgtttt ggaatgaaat ttggtcagat aatatgatta cggtgagttc tgtaacagct    660

actggtaata tttttgtaaa tcacgtgaaa gcattggagc aactgtcttg gaaaatgctc    720

tttaaacttc aaaccccagt atgttttggt agtagtggat attacacata tatgctgctc    780

ttttcagtgt tcttttattg tgcgaaaaca tttttaaaac atttgattta ttaataggat    840

ttatttttaa taggattgtt aataggattt atttttctag gacattgtct ttaaacactt    900

ggatgatttt atatgtctta attctttaat aatttgtaga tttaaaaaac ttcgtgggca    960

gaaagcgaag aaataggaaa ggatatagat ttatttggca tttcaaagga ttttgtttta   1020

ttatcccctc ttatttgggt ataaactcaa atctatttta tccttcatct gtttggattg   1080

atgtgtattg agattttgtc taattgaact gattttgata acacataaag tttaatttcc   1140

ctgttaaaat aggactccca aatttctgaa tgtctgtttc aagtattagg ttacctcagt   1200

tttctggcac ctaaaagcta ctgataacat acattagtag caatattaaa taaggtaaaa   1260

taactccagt gacatcctag ttacatgctt ggggtgggtt tttggtttcg ttttaaagta   1320

tttatgaggg atactttcat gcattttcca tgaaactaat ttttctcttt ctttttttag   1380

cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct   1440

ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg   1500

atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt   1560

cagctcaggt attttcatct ttttttataa atgatgttag gttgttcgtc tctaccttaa   1620

tcttcgcaca ttatgtggtg catgttatgg ttaaccgtct tccattatag tttttgtgtg   1680

tgtgtgcctg aaagtagctt taatatagtg gctaaataaa ccctccaaaa taaaagaaaa   1740

tcagtaacaa tttgatcagg gtatgagagg atttctagta atgctcaaag cttgccatga   1800

aatcttggca tcttgattca ttcttaggct gcatacaaat cgtagagaaa agataaaacg   1860

gcaaatttga gagtagaagt cattttttaa taaaattcta gtatacctat tagccagtgg   1920

aaccattatg gtaaaccagt ttgtggttat agagcactaa gtttctacag gcaacttgaa   1980

taaacataac ttgggtccat tttgcataca gcaacatctt tacctttttt ttcatttttt   2040

ctgtagggca atgtgtatgt gaagtgccca tcaattgctg cagctattgc tgctgtcaat   2100

gcattgcatg gcaggtggtt tgctggtaaa atgataacag cagcatatgt acctcttcca   2160

acttaccaca acctgtttcc tgattctatg acagcaacac agctactggt tccaagtaga   2220

cgatgaagga agatatagtc ccttatgtat atagcttttt ttctttcttg agaattcatc   2280

ttgagttatc ttttatttag ataaaaataa agaggcaagg atctactgtc atttgtatgc   2340

aatttcctgt taccttgaaa aaataaaaat gttaacagg                          2379


<210>  9908
<211>  106
<212>  PRT
<213>  Homo sapiens

<400>  9908

Met Lys Leu Ile Phe Leu Phe Leu Phe Leu Ala Ser Ala Leu Ala Ala 
1               5                   10                  15


Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn 
            20                  25                  30


Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile 
        35                  40                  45


Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His 
    50                  55                  60


Ile Tyr Val Asp Lys Asn Ser Ala Gln Val Phe Ser Ser Phe Phe Ile 
65                  70                  75                  80


Asn Asp Val Arg Leu Phe Val Ser Thr Leu Ile Phe Ala His Tyr Val 
                85                  90                  95


Val His Val Met Val Asn Arg Leu Pro Leu 
            100                 105


<210>  9909
<211>  831
<212>  DNA
<213>  Homo sapiens

<400>  9909
gggatttaag tgaaccacct cccttggcct cccagagtgc tagctaagtt acaggcgtca     60

accaccacac tcggccctcc ttgcaattta ttttagtgaa gtgatcatga tattaatgac    120

ccaggaaact tcgtttctct gctctcaaca tagtaggaac tttaagacta ttcttttaca    180

ggtacaggtt tgcagattcc gccagcagca cagcaagctc tacagatgag tggctctttg    240

gcatttggtg ctgtggcaga attctctttt gttatagatt tgcaaacaag actttcccag    300

cagactgaag cttcagcttt agctgcagct gcctctgttc agccacttgc aacacaatgt    360

ttccaactct ctaacatgtt taaccctcaa acagaagaag aagttggatg ggataccgag    420

attaaggatg atgtgattga agaatgtaat aaacatggag gagttattca tatttatgtt    480

gacaaaaatt cagctcaggg caatgtgtat gtgaagtgcc catcaattgc tgcagctatt    540

gctgctgtca atgcattgca tggcaggtgg tttgctggta aaatgataac agcagcatat    600

gtacctcttc caacttacca caacctgttt cctgattcta tgacagcaac acagctactg    660

gttccaagta gacgatgaag gaagatatag tcccttatgt atatagcttt ttttctttct    720

tgagaattca tcttgagtta tcttttattt agataaaaat aaagaggcaa ggatctactg    780

tcatttgtat gcaatttcct gttaccttga aaaaataaaa atgttaacag g             831


<210>  9910
<211>  150
<212>  PRT
<213>  Homo sapiens

<400>  9910

Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val 
1               5                   10                  15


Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu 
            20                  25                  30


Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu 
        35                  40                  45


Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr 
    50                  55                  60


Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val 
65                  70                  75                  80


Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val 
                85                  90                  95


Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His 
            100                 105                 110


Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu 
        115                 120                 125


Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu 
    130                 135                 140


Leu Val Pro Ser Arg Arg 
145                 150


<210>  9911
<211>  2339
<212>  DNA
<213>  Homo sapiens

<400>  9911
attctattgt aagtttgttt tattaattta ttttgtggat tacagtaatg cttttgttgg     60

cctgttgtat gacaaactat ttaaaggttc acattttgat ttgtatttgc caacaagccc    120

ttttgcttgt taaagctata gctaactctc aggagataat tgcagttcta ctcttagagg    180

atggtgtctt tcaaataatg tcttgtctgc tgattttcag taatgttaat ataaggcaaa    240

agggatattg tttactatac gtagcaattt ttttagacag agtcttactc tgtcgcccag    300

gctggagtac cagtggcggg atcttggctc actgcaacct ccgcttcccg ggtttgagca    360

attctcctgc cttagcctcc cgagtagctg ggactacagg cgcacggtac tatgcccggc    420

taatttttgt atttttatta gggacggggt ttcactacat tggccagact ggtcttgaac    480

tcctgacctt gtgatctgcc tgcctcggcc taccaaagtg ctgagattac aggatttttt    540

ttttttttta agtatgatta tgtaccattg tatcatagta aaactagcca aagaaattta    600

tgaaaggatg aaaaaatgat tctggccata aaaggtagta tattttggtg ggttcttaag    660

ccagcatgat aatggcgagt ttttttcttc tcaggaggaa aaaaagcaag agcagaagtc    720

gtagtcatga acgaaagaga agcaaaagta aggaacggaa gcgaagtaga gacagagaaa    780

ggaaaaagag caaaagccgt gaaagaaagc gaagtagaag caaagagagg cgacggagcc    840

gctcaagaag tcgagatcga agatttagag gccgctacag aagtccttac tccggaccaa    900

aatttaacag tgccatccga ggaaagattg ggttgcctca tagcatcaaa ttaagcagac    960

gacgttcccg aagcaaaagt ccattcagaa aagacaagag ccctgtgaga gaacctattg   1020

ataatttaac tcctgaggaa agagatgcaa ggacagtctt ctgtatgcag ctggcggcaa   1080

gaattcgacc aagggatttg gaagagtttt tctctacagt aggaaaggtt cgagatgtga   1140

ggatgatttc tgacagaaat tcaagacgtt ccaaaggaat tgcttatgtg gagttcgtcg   1200

atgttagctc agtgcctcta gcaataggat taactggcca acgagtttta ggcgtgccaa   1260

tcatagtaca ggcatcacag gcagaaaaaa acagagctgc agcaatggca aacaatttac   1320

aaaagggaag tgctggacct atgaggcttt atgtgggctc attacacttc aacataactg   1380

aagatatgct tcgtgggatc tttgagcctt ttggaagaat tgaaagtatc cagctgatga   1440

tggacagtga aactggtcga tccaagggat atggatttat tacattttct gactcagaat   1500

gtgccaaaaa ggctttggaa caacttaatg gatttgaact agcaggaaga ccaatgaaag   1560

ttggtcatgt tactgaacgt actgatgctt cgagtgctag ttcatttttg gacagtgatg   1620

aactggaaag gactggaatt gatttgggaa caactggtcg tcttcagtta atggcaagac   1680

ttgcagaggg tacaggtttg cagattccgc cagcagcaca gcaagctcta cagatgagtg   1740

gctctttggc atttggtgct gtggcagaat tctcttttgt tatagatttg caaacaagac   1800

tttcccagca gactgaagct tcagctttag ctgcagctgc ctctgttcag ccacttgcaa   1860

cacaatgttt ccaactctct aacatgttta accctcaaac agaagaagaa gttggatggg   1920

ataccgagat taaggatgat gtgattgaag aatgtaataa acatggagga gttattcata   1980

tttatgttga caaaaattca gctcagggca atgtgtatgt gaagtgccca tcaattgctg   2040

cagctattgc tgctgtcaat gcattgcatg gcaggtggtt tgctggtaaa atgataacag   2100

cagcatatgt acctcttcca acttaccaca acctgtttcc tgattctatg acagcaacac   2160

agctactggt tccaagtaga cgatgaagga agatatagtc ccttatgtat atagcttttt   2220

ttctttcttg agaattcatc ttgagttatc ttttatttag ataaaaataa agaggcaagg   2280

atctactgtc atttgtatgc aatttcctgt taccttgaaa aaataaaaat gttaacagg    2339


<210>  9912
<211>  506
<212>  PRT
<213>  Homo sapiens

<400>  9912

Met Ile Met Ala Ser Phe Phe Leu Leu Arg Arg Lys Lys Ser Lys Ser 
1               5                   10                  15


Arg Ser Arg Ser His Glu Arg Lys Arg Ser Lys Ser Lys Glu Arg Lys 
            20                  25                  30


Arg Ser Arg Asp Arg Glu Arg Lys Lys Ser Lys Ser Arg Glu Arg Lys 
        35                  40                  45


Arg Ser Arg Ser Lys Glu Arg Arg Arg Ser Arg Ser Arg Ser Arg Asp 
    50                  55                  60


Arg Arg Phe Arg Gly Arg Tyr Arg Ser Pro Tyr Ser Gly Pro Lys Phe 
65                  70                  75                  80


Asn Ser Ala Ile Arg Gly Lys Ile Gly Leu Pro His Ser Ile Lys Leu 
                85                  90                  95


Ser Arg Arg Arg Ser Arg Ser Lys Ser Pro Phe Arg Lys Asp Lys Ser 
            100                 105                 110


Pro Val Arg Glu Pro Ile Asp Asn Leu Thr Pro Glu Glu Arg Asp Ala 
        115                 120                 125


Arg Thr Val Phe Cys Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp 
    130                 135                 140


Leu Glu Glu Phe Phe Ser Thr Val Gly Lys Val Arg Asp Val Arg Met 
145                 150                 155                 160


Ile Ser Asp Arg Asn Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu 
                165                 170                 175


Phe Val Asp Val Ser Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln 
            180                 185                 190


Arg Val Leu Gly Val Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys 
        195                 200                 205


Asn Arg Ala Ala Ala Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly 
    210                 215                 220


Pro Met Arg Leu Tyr Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp 
225                 230                 235                 240


Met Leu Arg Gly Ile Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln 
                245                 250                 255


Leu Met Met Asp Ser Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile 
            260                 265                 270


Thr Phe Ser Asp Ser Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn 
        275                 280                 285


Gly Phe Glu Leu Ala Gly Arg Pro Met Lys Val Gly His Val Thr Glu 
    290                 295                 300


Arg Thr Asp Ala Ser Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu 
305                 310                 315                 320


Glu Arg Thr Gly Ile Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met 
                325                 330                 335


Ala Arg Leu Ala Glu Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln 
            340                 345                 350


Gln Ala Leu Gln Met Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu 
        355                 360                 365


Phe Ser Phe Val Ile Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu 
    370                 375                 380


Ala Ser Ala Leu Ala Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln 
385                 390                 395                 400


Cys Phe Gln Leu Ser Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val 
                405                 410                 415


Gly Trp Asp Thr Glu Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys 
            420                 425                 430


His Gly Gly Val Ile His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly 
        435                 440                 445


Asn Val Tyr Val Lys Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val 
    450                 455                 460


Asn Ala Leu His Gly Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala 
465                 470                 475                 480


Tyr Val Pro Leu Pro Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr 
                485                 490                 495


Ala Thr Gln Leu Leu Val Pro Ser Arg Arg 
            500                 505


<210>  9913
<211>  523
<212>  DNA
<213>  Homo sapiens

<400>  9913
ggtgaatgtg agtacaggga agcagcggcc gccatttcag ggagcttgtc gacgctgtcg     60

caggggtgga tcctgagctg ccgaagccgc cgtcctgctc tcccgcgtgg gcttctctaa    120

ttccattgtt ttttttagat tctctcgggc ctagccgtcc ttggaacccg atattcgggc    180

tgggcggttc cgcggcctgg gcctagggtg cccatcaatt gctgcagcta ttgctgctgt    240

caatgcattg catggcaggt ggtttgctgg taaaatgata acagcagcat atgtacctct    300

tccaacttac cacaacctgt ttcctgattc tatgacagca acacagctac tggttccaag    360

tagacgatga aggaagatat agtcccttat gtatatagct ttttttcttt cttgagaatt    420

catcttgagt tatcttttat ttagataaaa ataaagaggc aaggatctac tgtcatttgt    480

atgcaatttc ctgttacctt gaaaaaataa aaatgttaac agg                      523


<210>  9914
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9914

Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr Tyr His Asn Leu Phe 
1               5                   10                  15


Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val Pro Ser Arg Arg 
            20                  25                  30


<210>  9915
<211>  2161
<212>  DNA
<213>  Homo sapiens

<400>  9915
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa    420

cggccatgaa gaacgtagca aaaaacaaac tttctgcctc cttggaaagc tctacatctc    480

cttgtgattg gagtgtgggt ttcaagattc cagaaggagg aaaaaaagca agagcagaag    540

tcgtagtcat gaacgaaaga gaagcaaaag taaggaacgg aagcgaagta gagacagaga    600

aaggaaaaag agcaaaagcc gtgaaagaaa gcgaagtaga agcaaagaga ggcgacggag    660

ccgctcaaga agtcgagatc gaagatttag aggccgctac agaagtcctt actccggacc    720

aaaatttaac agtgccatcc gaggaaagat tgggttgcct catagcatca aattaagcag    780

acgacgttcc cgaagcaaaa gtccattcag aaaagacaag agccctgtga gagaacctat    840

tgataattta actcctgagg aaagagatgc aaggacagtc ttctgtatgc agctggcggc    900

aagaattcga ccaagggatt tggaagagtt tttctctaca gtaggaaagg ttcgagatgt    960

gaggatgatt tctgacagaa attcaagacg ttccaaagga attgcttatg tggagttcgt   1020

cgatgttagc tcagtgcctc tagcaatagg attaactggc caacgagttt taggcgtgcc   1080

aatcatagta caggcatcac aggcagaaaa aaacagagct gcagcaatgg caaacaattt   1140

acaaaaggga agtgctggac ctatgaggct ttatgtgggc tcattacact tcaacataac   1200

tgaagatatg cttcgtggga tctttgagcc ttttggaaga attgaaagta tccagctgat   1260

gatggacagt gaaactggtc gatccaaggg atatggattt attacatttt ctgactcaga   1320

atgtgccaaa aaggctttgg aacaacttaa tggatttgaa ctagcaggaa gaccaatgaa   1380

agttggtcat gttactgaac gtactgatgc ttcgagtgct agttcatttt tggacagtga   1440

tgaactggaa aggactggaa ttgatttggg aacaactggt cgtcttcagt taatggcaag   1500

acttgcagag ggtacaggtt tgcagattcc gccagcagca cagcaagctc tacagatgag   1560

tggctctttg gcatttggtg ctgtggcaga attctctttt gttatagatt tgcaaacaag   1620

actttcccag cagactgaag cttcagcttt agctgcagct gcctctgttc agccacttgc   1680

aacacaatgt ttccaactct ctaacatgtt taaccctcaa acagaagaag aagttggatg   1740

ggataccgag attaaggatg atgtgattga agaatgtaat aaacatggag gagttattca   1800

tatttatgtt gacaaaaatt cagctcaggg caatgtgtat gtgaagtgcc catcaattgc   1860

tgcagctatt gctgctgtca atgcattgca tggcaggtgg tttgctggta aaatgataac   1920

agcagcatat gtacctcttc caacttacca caacctgttt cctgattcta tgacagcaac   1980

acagctactg gttccaagta gacgatgaag gaagatatag tcccttatgt atatagcttt   2040

ttttctttct tgagaattca tcttgagtta tcttttattt agataaaaat aaagaggcaa   2100

ggatctactg tcatttgtat gcaatttcct gttaccttga aaaaataaaa atgttaacag   2160

g                                                                   2161


<210>  9916
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9916

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9917
<211>  2131
<212>  DNA
<213>  Homo sapiens

<400>  9917
gcgagagccc gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc     60

tggtgaatgt gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc    120

gcaggggtgg atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta    180

attccattgt tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg    240

ctgggcggtt ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc    300

ggcagcagca gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga    360

aggccggaac aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga    420

ggctccttac aagaaggatg agaacaagtt gagcagtgcc aacggccatg aagaacgtag    480

caaaaagagg aaaaaaagca agagcagaag tcgtagtcat gaacgaaaga gaagcaaaag    540

taaggaacgg aagcgaagta gagacagaga aaggaaaaag agcaaaagcc gtgaaagaaa    600

gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga agtcgagatc gaagatttag    660

aggccgctac agaagtcctt actccggacc aaaatttaac agtgccatcc gaggaaagat    720

tgggttgcct catagcatca aattaagcag acgacgttcc cgaagcaaaa gtccattcag    780

aaaagacaag agccctgtga gagaacctat tgataattta actcctgagg aaagagatgc    840

aaggacagtc ttctgtatgc agctggcggc aagaattcga ccaagggatt tggaagagtt    900

tttctctaca gtaggaaagg ttcgagatgt gaggatgatt tctgacagaa attcaagacg    960

ttccaaagga attgcttatg tggagttcgt cgatgttagc tcagtgcctc tagcaatagg   1020

attaactggc caacgagttt taggcgtgcc aatcatagta caggcatcac aggcagaaaa   1080

aaacagagct gcagcaatgg caaacaattt acaaaaggga agtgctggac ctatgaggct   1140

ttatgtgggc tcattacact tcaacataac tgaagatatg cttcgtggga tctttgagcc   1200

ttttggaaga attgaaagta tccagctgat gatggacagt gaaactggtc gatccaaggg   1260

atatggattt attacatttt ctgactcaga atgtgccaaa aaggctttgg aacaacttaa   1320

tggatttgaa ctagcaggaa gaccaatgaa agttggtcat gttactgaac gtactgatgc   1380

ttcgagtgct agttcatttt tggacagtga tgaactggaa aggactggaa ttgatttggg   1440

aacaactggt cgtcttcagt taatggcaag acttgcagag ggtacaggtt tgcagattcc   1500

gccagcagca cagcaagctc tacagatgag tggctctttg gcatttggtg ctgtggcaga   1560

attctctttt gttatagatt tgcaaacaag actttcccag cagactgaag cttcagcttt   1620

agctgcagct gcctctgttc agccacttgc aacacaatgt ttccaactct ctaacatgtt   1680

taaccctcaa acagaagaag aagttggatg ggataccgag attaaggatg atgtgattga   1740

agaatgtaat aaacatggag gagttattca tatttatgtt gacaaaaatt cagctcaggg   1800

caatgtgtat gtgaagtgcc catcaattgc tgcagctatt gctgctgtca atgcattgca   1860

tggcaggtgg tttgctggta aaatgataac agcagcatat gtacctcttc caacttacca   1920

caacctgttt cctgattcta tgacagcaac acagctactg gttccaagta gacgatgaag   1980

gaagatatag tcccttatgt atatagcttt ttttctttct tgagaattca tcttgagtta   2040

tcttttattt agataaaaat aaagaggcaa ggatctactg tcatttgtat gcaatttcct   2100

gttaccttga aaaaataaaa atgttaacag g                                  2131


<210>  9918
<211>  530
<212>  PRT
<213>  Homo sapiens

<400>  9918

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Arg Lys Lys Ser Lys Ser Arg Ser Arg Ser His Glu Arg Lys 
        35                  40                  45


Arg Ser Lys Ser Lys Glu Arg Lys Arg Ser Arg Asp Arg Glu Arg Lys 
    50                  55                  60


Lys Ser Lys Ser Arg Glu Arg Lys Arg Ser Arg Ser Lys Glu Arg Arg 
65                  70                  75                  80


Arg Ser Arg Ser Arg Ser Arg Asp Arg Arg Phe Arg Gly Arg Tyr Arg 
                85                  90                  95


Ser Pro Tyr Ser Gly Pro Lys Phe Asn Ser Ala Ile Arg Gly Lys Ile 
            100                 105                 110


Gly Leu Pro His Ser Ile Lys Leu Ser Arg Arg Arg Ser Arg Ser Lys 
        115                 120                 125


Ser Pro Phe Arg Lys Asp Lys Ser Pro Val Arg Glu Pro Ile Asp Asn 
    130                 135                 140


Leu Thr Pro Glu Glu Arg Asp Ala Arg Thr Val Phe Cys Met Gln Leu 
145                 150                 155                 160


Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe Ser Thr Val 
                165                 170                 175


Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn Ser Arg Arg 
            180                 185                 190


Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser Ser Val Pro 
        195                 200                 205


Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val Pro Ile Ile 
    210                 215                 220


Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala Met Ala Asn 
225                 230                 235                 240


Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr Val Gly Ser 
                245                 250                 255


Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile Phe Glu Pro 
            260                 265                 270


Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser Glu Thr Gly 
        275                 280                 285


Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser Glu Cys Ala 
    290                 295                 300


Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala Gly Arg Pro 
305                 310                 315                 320


Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser Ser Ala Ser 
                325                 330                 335


Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile Asp Leu Gly 
            340                 345                 350


Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu Gly Thr Gly 
        355                 360                 365


Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met Ser Gly Ser 
    370                 375                 380


Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile Asp Leu Gln 
385                 390                 395                 400


Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala Ala Ala Ala 
                405                 410                 415


Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser Asn Met Phe 
            420                 425                 430


Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu Ile Lys Asp 
        435                 440                 445


Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile His Ile Tyr 
    450                 455                 460


Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys Cys Pro Ser 
465                 470                 475                 480


Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly Arg Trp Phe 
                485                 490                 495


Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro Thr Tyr His 
            500                 505                 510


Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu Val Pro Ser 
        515                 520                 525


Arg Arg 
    530


<210>  9919
<211>  2230
<212>  DNA
<213>  Homo sapiens

<400>  9919
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaagagga aaaaaagcaa    600

gagcagaagt cgtagtcatg aacgaaagag aagcaaaagt aaggaacgga agcgaagtag    660

agacagagaa aggaaaaaga gcaaaagccg tgaaagaaag cgaagtagaa gcaaagagag    720

gcgacggagc cgctcaagaa gtcgagatcg aagatttaga ggccgctaca gaagtcctta    780

ctccggacca aaatttaaca gtgccatccg aggaaagatt gggttgcctc atagcatcaa    840

attaagcaga cgacgttccc gaagcaaaag tccattcaga aaagacaaga gccctgtgag    900

agaacctatt gataatttaa ctcctgagga aagagatgca aggacagtct tctgtatgca    960

gctggcggca agaattcgac caagggattt ggaagagttt ttctctacag taggaaaggt   1020

tcgagatgtg aggatgattt ctgacagaaa ttcaagacgt tccaaaggaa ttgcttatgt   1080

ggagttcgtc gatgttagct cagtgcctct agcaatagga ttaactggcc aacgagtttt   1140

aggcgtgcca atcatagtac aggcatcaca ggcagaaaaa aacagagctg cagcaatggc   1200

aaacaattta caaaagggaa gtgctggacc tatgaggctt tatgtgggct cattacactt   1260

caacataact gaagatatgc ttcgtgggat ctttgagcct tttggaagaa ttgaaagtat   1320

ccagctgatg atggacagtg aaactggtcg atccaaggga tatggattta ttacattttc   1380

tgactcagaa tgtgccaaaa aggctttgga acaacttaat ggatttgaac tagcaggaag   1440

accaatgaaa gttggtcatg ttactgaacg tactgatgct tcgagtgcta gttcattttt   1500

ggacagtgat gaactggaaa ggactggaat tgatttggga acaactggtc gtcttcagtt   1560

aatggcaaga cttgcagagg gtacaggttt gcagattccg ccagcagcac agcaagctct   1620

acagatgagt ggctctttgg catttggtgc tgtggcagaa ttctcttttg ttatagattt   1680

gcaaacaaga ctttcccagc agactgaagc ttcagcttta gctgcagctg cctctgttca   1740

gccacttgca acacaatgtt tccaactctc taacatgttt aaccctcaaa cagaagaaga   1800

agttggatgg gataccgaga ttaaggatga tgtgattgaa gaatgtaata aacatggagg   1860

agttattcat atttatgttg acaaaaattc agctcagggc aatgtgtatg tgaagtgccc   1920

atcaattgct gcagctattg ctgctgtcaa tgcattgcat ggcaggtggt ttgctggtaa   1980

aatgataaca gcagcatatg tacctcttcc aacttaccac aacctgtttc ctgattctat   2040

gacagcaaca cagctactgg ttccaagtag acgatgaagg aagatatagt cccttatgta   2100

tatagctttt tttctttctt gagaattcat cttgagttat cttttattta gataaaaata   2160

aagaggcaag gatctactgt catttgtatg caatttcctg ttaccttgaa aaaataaaaa   2220

tgttaacagg                                                          2230


<210>  9920
<211>  373
<212>  PRT
<213>  Homo sapiens

<400>  9920

Met Gln Leu Ala Ala Arg Ile Arg Pro Arg Asp Leu Glu Glu Phe Phe 
1               5                   10                  15


Ser Thr Val Gly Lys Val Arg Asp Val Arg Met Ile Ser Asp Arg Asn 
            20                  25                  30


Ser Arg Arg Ser Lys Gly Ile Ala Tyr Val Glu Phe Val Asp Val Ser 
        35                  40                  45


Ser Val Pro Leu Ala Ile Gly Leu Thr Gly Gln Arg Val Leu Gly Val 
    50                  55                  60


Pro Ile Ile Val Gln Ala Ser Gln Ala Glu Lys Asn Arg Ala Ala Ala 
65                  70                  75                  80


Met Ala Asn Asn Leu Gln Lys Gly Ser Ala Gly Pro Met Arg Leu Tyr 
                85                  90                  95


Val Gly Ser Leu His Phe Asn Ile Thr Glu Asp Met Leu Arg Gly Ile 
            100                 105                 110


Phe Glu Pro Phe Gly Arg Ile Glu Ser Ile Gln Leu Met Met Asp Ser 
        115                 120                 125


Glu Thr Gly Arg Ser Lys Gly Tyr Gly Phe Ile Thr Phe Ser Asp Ser 
    130                 135                 140


Glu Cys Ala Lys Lys Ala Leu Glu Gln Leu Asn Gly Phe Glu Leu Ala 
145                 150                 155                 160


Gly Arg Pro Met Lys Val Gly His Val Thr Glu Arg Thr Asp Ala Ser 
                165                 170                 175


Ser Ala Ser Ser Phe Leu Asp Ser Asp Glu Leu Glu Arg Thr Gly Ile 
            180                 185                 190


Asp Leu Gly Thr Thr Gly Arg Leu Gln Leu Met Ala Arg Leu Ala Glu 
        195                 200                 205


Gly Thr Gly Leu Gln Ile Pro Pro Ala Ala Gln Gln Ala Leu Gln Met 
    210                 215                 220


Ser Gly Ser Leu Ala Phe Gly Ala Val Ala Glu Phe Ser Phe Val Ile 
225                 230                 235                 240


Asp Leu Gln Thr Arg Leu Ser Gln Gln Thr Glu Ala Ser Ala Leu Ala 
                245                 250                 255


Ala Ala Ala Ser Val Gln Pro Leu Ala Thr Gln Cys Phe Gln Leu Ser 
            260                 265                 270


Asn Met Phe Asn Pro Gln Thr Glu Glu Glu Val Gly Trp Asp Thr Glu 
        275                 280                 285


Ile Lys Asp Asp Val Ile Glu Glu Cys Asn Lys His Gly Gly Val Ile 
    290                 295                 300


His Ile Tyr Val Asp Lys Asn Ser Ala Gln Gly Asn Val Tyr Val Lys 
305                 310                 315                 320


Cys Pro Ser Ile Ala Ala Ala Ile Ala Ala Val Asn Ala Leu His Gly 
                325                 330                 335


Arg Trp Phe Ala Gly Lys Met Ile Thr Ala Ala Tyr Val Pro Leu Pro 
            340                 345                 350


Thr Tyr His Asn Leu Phe Pro Asp Ser Met Thr Ala Thr Gln Leu Leu 
        355                 360                 365


Val Pro Ser Arg Arg 
    370


<210>  9921
<211>  2506
<212>  DNA
<213>  Homo sapiens

<400>  9921
gtcttttaaa gctattgggt gaaactaggg atgggtcatc actatatcca cattatttta     60

ttctgccagt ttgataggcc ctttctaaaa taggttagag tccttatctt tatgaaaacc    120

atgctttatt tttcactttg tcacaaatga tatgacaaat catttttgaa attatgattg    180

ggttggtaga caaaatagca tggatttctg atatctatac attttttccc attttaggaa    240

aaaaaagaca aattctgtta ttatttaaag tttattgaca ctgttcacat ggtcctatct    300

tcaagttcct tcagtataca ccagttacat ttcttcagct ccctgagatg ccaattttga    360

gcacctagga cccagatttg caaacaagac tttcccagca gactgaaggt gagttgaagt    420

gttcatattt tttatttttg tctttgaaat agaattaaat gtagtaagac agttttctat    480

atttattgtc atatttttat accagtaatt tggaccaaat tttgacacag tgacacatag    540

tggtatattc atagtaatct gtctgtattt cagaagacct aacccaaatt aatggactta    600

aaaaaaatca aaataacaat tttttttttt gctttagttt gcttaaaatt ttcaaccttg    660

tttttgtttt atgcctacct gtgtgttcta agtgttgata agttgcatat agaagtcagg    720

aaatgaagta ttctcttatt aacgagtagg caagtatttt agaacctgga atctggaagt    780

tgtcttagta taaagttgtg aatcatgcta taaaactcac ctttttttgc ttaagacata    840

gtactcagtg atttatttaa gccagtacca agcaataaga ggtttataca tacttaaatt    900

acatgcacat ttcagagaaa ccattcatta agtaggctat gatttcttgt ttttagttat    960

cactaaatct ctgttgcttg acatgagcat tttgctgtta atgtaagttc tatatctttt   1020

gtaggagtat gcttaatgtt tagggaaatg attatgagaa agatatgtca tgttccatca   1080

cagtcaagaa ttaaattttt tcacaaacaa gatgcttcta atcagtgctg ttttgttaag   1140

agatttttaa aagattttcc tagatttact gtgttctgca ttgatctagc ttgaacgtga   1200

atgtttgtat agtacgtttt cttaatattt tttagtattc atagtatata atcatactaa   1260

acttgagaaa ctggaagaat caagtcttcc tcagttctgt ttagactttc tagttttttt   1320

taaggatact tccatatctt ctgtaagcta cacagtgagc ttcatttttg cacagttata   1380

atacactctc gaatctttaa cttttttcca gcagaatttg acatgttata ttaaaatttt   1440

gttttattta aaataaaact ttatgaaaga aaaaacttat atgttacaga gaagctaaag   1500

cacctgtaat gctaccagaa agttatcatt tatgatatat ttcatgcaca gccctaattt   1560

ctcggtgtaa tatttctgat actttaagtg atcgtttatt ttaattacca taatttctaa   1620

tgcactgttt tatccttagc tttgtttgtt attatgtttt ggaatgaaat ttggtcagat   1680

aatatgatta cggtgagttc tgtaacagct actggtaata tttttgtaaa tcacgtgaaa   1740

gcattggagc aactgtcttg gaaaatgctc tttaaacttc aaaccccagt atgttttggt   1800

agtagtggat attacacata tatgctgctc ttttcagtgt tcttttattg tgcgaaaaca   1860

tttttaaaac atttgattta ttaataggat ttatttttaa taggattgtt aataggattt   1920

atttttctag gacattgtct ttaaacactt ggatgatttt atatgtctta attctttaat   1980

aatttgtaga tttaaaaaac ttcgtgggca gaaagcgaag aaataggaaa ggatatagat   2040

ttatttggca tttcaaagga ttttgtttta ttatcccctc ttatttgggt ataaactcaa   2100

atctatttta tccttcatct gtttggattg atgtgtattg agattttgtc taattgaact   2160

gattttgata acacataaag tttaatttcc ctgttaaaat aggactccca aatttctgaa   2220

tgtctgtttc aagtattagg ttacctcagt tttctggcac ctaaaagcta ctgataacat   2280

acattagtag caatattaaa taaggtaaaa taactccagt gacatcctag ttacatgctt   2340

ggggtgggtt tttggtttcg ttttaaagta tttatgaggg atactttcat gcattttcca   2400

tgaaactaat ttttctcttt ctttttttag cttcagcttt agctgcagct gcctctgttc   2460

agccacttgc aacacaatgt ttccaactct ctaacatgtt taaccc                  2506


<210>  9922
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  9922

Met Phe Trp Asn Glu Ile Trp Ser Asp Asn Met Ile Thr Val Ser Ser 
1               5                   10                  15


Val Thr Ala Thr Gly Asn Ile Phe Val Asn His Val Lys Ala Leu Glu 
            20                  25                  30


Gln Leu Ser Trp Lys Met Leu Phe Lys Leu Gln Thr Pro Val Cys Phe 
        35                  40                  45


Gly Ser Ser Gly Tyr Tyr Thr Tyr Met Leu Leu Phe Ser Val Phe Phe 
    50                  55                  60


Tyr Cys Ala Lys Thr Phe Leu Lys His Leu Ile Tyr 
65                  70                  75


<210>  9923
<211>  652
<212>  DNA
<213>  Homo sapiens

<400>  9923
tttttttttt tttttaactt tgcgtttatt aacattgata cagttttctc aagactgtcg     60

tcctgtcgtt tctccttgtg tttgaaatgt aatgattttg cctttttttt gttttgtttt    120

tgagatggag tctctctcac caggctggag tgcaatggca tgatcgctgc tcactgcaac    180

ctccacctcc tgggttcaag cgctactcag gaggccgagg caggagaatt gcttaaaccc    240

aggaggcaga ggttgcagtg aggcaagatc acgccattgc actgcagcct gggcgacaag    300

aaccaagact gtgtctcaaa aagaaaaaag agttactcaa attatttcct atgttggaag    360

acaaacttag tggctgggtg tgcattggcg ggacccaggg ctgagaagta gcatattaag    420

tgaggtttta aattcatgca gcaacctgtt gtagagcagt actatccaat gtactctagt    480

ttgttacaag agaagcctgt gttagaatgc aaatggacaa cttttctttt tttttttttt    540

tgaggcgatc ttggttatgg agggatgaca gctgactcaa aatgtttgct tggtgataca    600

gttttatgtt atggcatata caccttattt tatcacaaac aactacgttc gg            652


<210>  9924
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  9924

Met Ile Ala Ala His Cys Asn Leu His Leu Leu Gly Ser Ser Ala Thr 
1               5                   10                  15


Gln Glu Ala Glu Ala Gly Glu Leu Leu Lys Pro Arg Arg Gln Arg Leu 
            20                  25                  30


Gln 



<210>  9925
<211>  660
<212>  DNA
<213>  Homo sapiens

<400>  9925
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa    420

cggccatgaa gaacgtagca aaaagaggaa aaaaagcaag aaattcgacc aagggatttg    480

gaagagtttt tctctacagt aggaaaggtt cgagatgtga ggatgatttc tgacagaaat    540

tcaagacgtt ccaaaggaat tgcttatgtg gagttcgtcg atgttagctc agtgcctcta    600

gcaataggat taactggcca acgagtttta ggcgtgccaa tcatagtaca ggcatcacag    660


<210>  9926
<211>  52
<212>  PRT
<213>  Homo sapiens

<400>  9926

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Arg Lys Lys Ser Lys Lys Phe Asp Gln Gly Ile Trp Lys Ser 
        35                  40                  45


Phe Ser Leu Gln 
    50


<210>  9927
<211>  2023
<212>  DNA
<213>  Homo sapiens

<400>  9927
ttgtaatgct tagactcttg aagagctact ttctgtttta atgttaagat tcttgtgtct     60

tagttttttt taacatggat gtaattccat gtaaacaggt atggaagtag gaaatgttta    120

ggctggactt ggtggattat taattgactt tcttgggttc ttgggagtca acattactaa    180

agcagtgtga atccctgttt gcttcagggc gagatgtgtg acagaggtgg catcaagctc    240

ttacagtccc aaccctccaa cggaaatggg cgaagatctc aggaatggca tcggtcacag    300

gaaatcgata gtggctggct gctagcatgg ccacttgggg cttaggcaga aatagagcca    360

tggtactgac caaagggacc atagcacatg gaataaaact caaaacagga cttcatgttt    420

tatggaaatt atatttaacc acttcaacat tgtaaatctg gataactttt aatatctaaa    480

ctatataaga aagtaaaatt taacatgtta atatggaaaa tttttttatt tttgtatctt    540

gatgacttaa atgtaagcaa caaagtggtt aaacacatac ccatctaaat ttttttatag    600

ccttccatgt taaactataa gtaaataatt agttttaaaa ttgttttgta ttttcttatt    660

cctgttccct ttaccctttg acaacttgaa atgttaccac ttcgtcctca tgatgttctt    720

ctatcaaccc tgcttaggat gagaacaagt tgagcagtgc caacggccat gaagaacgta    780

gcaaaaagag gaaaaaaagc aagagcagaa gtcgtagtca tgaacgaaag agaagcaaaa    840

gtaaggaacg gaagcgaagt agagacagag aaaggaaaaa gagcaaaagc cgtgaaagaa    900

agcgaagtag aagcaaagag aggcgacgga gccgctcaag aagtcgagat cgaagattta    960

gaggccgcta cagaagtcct tagtatgtaa ctatagttat gattttggtt tgagggttat   1020

tctctgggta ttcagatggc agtttaactt gagtgatttg aattgtgaat ttttattttt   1080

ttaatgattg gttaaaaagt attgaattaa ggatattggc attgaatact agtaaagtga   1140

aaatacagtg catagacaaa taagtaaaaa tttgctttta ctaggcatac tgactatttt   1200

ctgttaaact atcagagttt ctaaattgta tgccagtcaa cgcaaactgg atgaaagcac   1260

tagagtgctt gaaaaagatg acattgtagt gcccaaatac ctaagaaagc ttaacaagtg   1320

tctgggctgt tacagtattt gctaaataca tatttactta aaattgtaaa gttctgatga   1380

atactaagtt acacatgtat aattagttaa cagtaaataa aaagtctgtc accgtggctg   1440

ttttcagctg aaatgtcagg ccagttgtga atttgttgtg tatgctcatt gataaagatc   1500

cttttttggg ctcatctgta tttaaggttt gttaataata ataaaaggta ttccaaacta   1560

aaagtgtttt gaagattaga tcactagaaa tttggatgtg gatatttaaa gttggaaaca   1620

aatatattat ggttattaaa taactatatt aaccacctac aattctaagg attgcatcta   1680

gcaatcttta atgctttatg aggttaattc ctcttaataa acacagtgct gtaaactctg   1740

ggatatatta aaaataaccc ttctaacttc taagatttga atggttaagg atggaattca   1800

aagacaaaca gacccgaatc acttgggcaa gatacttaat cccctaagct aagcatttgt   1860

tttctaacct tttaaggaga taataagttt cagataagct attaatgagt aatgaatgag   1920

aagaaaatgt aaagtgctca gaggacttaa tggattcatg aaatgttttg gcattacatg   1980

aattccgatt ctggctcttt tatctttaaa ataaaaagaa tta                     2023


<210>  9928
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  9928

Met Lys Asn Val Ala Lys Arg Gly Lys Lys Ala Arg Ala Glu Val Val 
1               5                   10                  15


Val Met Asn Glu Arg Glu Ala Lys Val Arg Asn Gly Ser Glu Val Glu 
            20                  25                  30


Thr Glu Lys Gly Lys Arg Ala Lys Ala Val Lys Glu Ser Glu Val Glu 
        35                  40                  45


Ala Lys Arg Gly Asp Gly Ala Ala Gln Glu Val Glu Ile Glu Asp Leu 
    50                  55                  60


Glu Ala Ala Thr Glu Val Leu Ser Met 
65                  70


<210>  9929
<211>  1742
<212>  DNA
<213>  Homo sapiens

<400>  9929
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaagagga aaaaaagcaa    600

gagcagaacc gtgaaagaaa gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga    660

agtcgagatc gaagatttag aggccgctac agaagtcctt agtatgtaac tatagttatg    720

attttggttt gagggttatt ctctgggtat tcagatggca gtttaacttg agtgatttga    780

attgtgaatt tttatttttt taatgattgg ttaaaaagta ttgaattaag gatattggca    840

ttgaatacta gtaaagtgaa aatacagtgc atagacaaat aagtaaaaat ttgcttttac    900

taggcatact gactattttc tgttaaacta tcagagtttc taaattgtat gccagtcaac    960

gcaaactgga tgaaagcact agagtgcttg aaaaagatga cattgtagtg cccaaatacc   1020

taagaaagct taacaagtgt ctgggctgtt acagtatttg ctaaatacat atttacttaa   1080

aattgtaaag ttctgatgaa tactaagtta cacatgtata attagttaac agtaaataaa   1140

aagtctgtca ccgtggctgt tttcagctga aatgtcaggc cagttgtgaa tttgttgtgt   1200

atgctcattg ataaagatcc ttttttgggc tcatctgtat ttaaggtttg ttaataataa   1260

taaaaggtat tccaaactaa aagtgttttg aagattagat cactagaaat ttggatgtgg   1320

atatttaaag ttggaaacaa atatattatg gttattaaat aactatatta accacctaca   1380

attctaagga ttgcatctag caatctttaa tgctttatga ggttaattcc tcttaataaa   1440

cacagtgctg taaactctgg gatatattaa aaataaccct tctaacttct aagatttgaa   1500

tggttaagga tggaattcaa agacaaacag acccgaatca cttgggcaag atacttaatc   1560

ccctaagcta agcatttgtt ttctaacctt ttaaggagat aataagtttc agataagcta   1620

ttaatgagta atgaatgaga agaaaatgta aagtgctcag aggacttaat ggattcatga   1680

aatgttttgg cattacatga attccgattc tggctctttt atctttaaaa taaaaagaat   1740

ta                                                                  1742


<210>  9930
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9930

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9931
<211>  1559
<212>  DNA
<213>  Homo sapiens

<400>  9931
ttgtaatgct tagactcttg aagagctact ttctgtttta atgttaagat tcttgtgtct     60

tagttttttt taacatggat gtaattccat gtaaacaggt atggaagtag gaaatgttta    120

ggctggactt ggtggattat taattgactt tcttgggttc ttgggagtca acattactaa    180

agcagtgtga atccctgttt gcttcagggc gagatgtgtg acagaggtgg catcaagctc    240

ttacagtccc aaccctccaa cggaaatggg cgaagatctc aggaatggca tcggtcacag    300

gaaatcgata gtggctggct gctagcatgg ccacttgggg cttaggcaga aatagagcca    360

tggtactgac caaagggacc atagcacatg gaataaaact caaaacagga cttcatgttt    420

tatggaaatt atatttaacc acttcaacat tgtaaatctg gataactttt aatatctaaa    480

ctatataaga aagtaaaatt taacatgtta atatggaaaa tttttttatt tttgtatctt    540

gatgacttaa atgtaagcaa caaagtggtt aaacacatac ccatctaaat ttttttatag    600

ccttccatgt taaactataa gtaaataatt agttttaaaa ttgttttgta ttttcttatt    660

cctgttccct ttaccctttg acaacttgaa atgttaccac ttcgtcctca tgatgttctt    720

ctatcaaccc tgcttaggat gagaacaagt tgagcagtgc caacggccat gaagaacgta    780

gcaaaaagag gaaaaaaagc aagagcagaa gtcgtagtca tgaacgaaag agaagcaaaa    840

gtaaggaacg gaagcgaagt agagacagag aaaggaaaaa gagcaaaagc cgtgaaagaa    900

agcgaagtag aagcaaagag aggcgacgga gccgctcaag aagtcgagat cgaagattta    960

gaggccgcta cagaagtcct tagtatgtaa ctatagttat gattttggtt tgagggttat   1020

tctctgggta ttcagatggc agtttaactt gagtgatttg aattgtgaat ttttattttt   1080

ttaatgattg gttaaaaagt attgaattaa ggatattggc attgaatact agtaaagtga   1140

aaatacagtg catagacaaa taagtaaaaa tttgctttta ctaggcatac tgactatttt   1200

ctgttaaact atcagagttt ctaaattgta tgccagtcaa cgcaaactgg atgaaagcac   1260

tagagtgctt gaaaaagatg acattgtagt gcccaaatac ctaagaaagc ttaacaagtg   1320

tctgggctgt tacagtattt gctaaataca tatttactta aaattgtaaa gttctgatga   1380

atactaagtt acacatgtat aattagttaa cagtaaataa aaagtctgtc accgtggctg   1440

ttttcagctg aaatgtcagg ccagttgtga atttgttgtg tatgctcatt gataaagatc   1500

cttttttggg ctcatctgta tttaaggttt gttaataata ataaaaggta ttccaaact    1559


<210>  9932
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  9932

Met Lys Asn Val Ala Lys Arg Gly Lys Lys Ala Arg Ala Glu Val Val 
1               5                   10                  15


Val Met Asn Glu Arg Glu Ala Lys Val Arg Asn Gly Ser Glu Val Glu 
            20                  25                  30


Thr Glu Lys Gly Lys Arg Ala Lys Ala Val Lys Glu Ser Glu Val Glu 
        35                  40                  45


Ala Lys Arg Gly Asp Gly Ala Ala Gln Glu Val Glu Ile Glu Asp Leu 
    50                  55                  60


Glu Ala Ala Thr Glu Val Leu Ser Met 
65                  70


<210>  9933
<211>  1278
<212>  DNA
<213>  Homo sapiens

<400>  9933
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaagagga aaaaaagcaa    600

gagcagaacc gtgaaagaaa gcgaagtaga agcaaagaga ggcgacggag ccgctcaaga    660

agtcgagatc gaagatttag aggccgctac agaagtcctt agtatgtaac tatagttatg    720

attttggttt gagggttatt ctctgggtat tcagatggca gtttaacttg agtgatttga    780

attgtgaatt tttatttttt taatgattgg ttaaaaagta ttgaattaag gatattggca    840

ttgaatacta gtaaagtgaa aatacagtgc atagacaaat aagtaaaaat ttgcttttac    900

taggcatact gactattttc tgttaaacta tcagagtttc taaattgtat gccagtcaac    960

gcaaactgga tgaaagcact agagtgcttg aaaaagatga cattgtagtg cccaaatacc   1020

taagaaagct taacaagtgt ctgggctgtt acagtatttg ctaaatacat atttacttaa   1080

aattgtaaag ttctgatgaa tactaagtta cacatgtata attagttaac agtaaataaa   1140

aagtctgtca ccgtggctgt tttcagctga aatgtcaggc cagttgtgaa tttgttgtgt   1200

atgctcattg ataaagatcc ttttttgggc tcatctgtat ttaaggtttg ttaataataa   1260

taaaaggtat tccaaact                                                 1278


<210>  9934
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9934

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9935
<211>  1800
<212>  DNA
<213>  Homo sapiens

<400>  9935
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaaaatac tttgcattaa    600

aaatttagat cttcttacat ggaagaggtc aaatccagtt atagcaaaac acctttactg    660

cagaggccat ataaccaaaa agtccaaagg cccagcccag tggaccattt acttcagtga    720

tgttcagtac aaaatttcac tgccattaaa gactttggaa agtccctttt aagttgtaac    780

aggatttgac tattagtgtg gatttcgata acccttcttt agttaatgta ataaatgctc    840

tttgaagctg gaaatatact ggtttcttgc acccttgtag ttttctctgg gcttttatgc    900

aaaagattgt attttctgaa tgtcttagta tgttgctgtc tttttacctg cctggggttg    960

ccttcagatg tgggtgagga cttgtttaca aaaagtccta gaagacctta agttaaaatt   1020

agctctccaa ttttcaagtg ttttcttttg gcagaataag ttttgggtcc tatgagaggt   1080

aaataggttg gttgcctctc ttgctatagc ccatctagag cagaacaaaa actttgtttt   1140

tgagggggat ggagttactt tttaccttgt tccctaattg aatatattta ggacttttgg   1200

ttttagaaat ctcagagttc tatagttgga atagtgtcac agagatagtg ttaggtttct   1260

taggcaacaa aattggagtg ttacctattg cccatctggg catggctttg atgagttcta   1320

tataaataat gagtgtagcc taattttctg tcatgtgcta cctagcatat acatttctga   1380

cagtcaggtg gattatcttg aaattttaga caaactttct gcctccttgg aaagctctac   1440

atctccttgt gattggagtg tgggtttcaa gattccagaa ggtgggtgtc ttcattttct   1500

attttcaatg cactctaaag atgacctgct tacaggttct ctgaggcaga cctcagttgc   1560

tcttgtgata tgtaactttg ctttgataag gaataaacaa ttacatatcc agataatgat   1620

acagaattgt caaaatgttt aatcattaag ccactacaaa tagacatttt cgtggaataa   1680

actgattttg aaatgtcttt caatttatat tgaaatatct gaaggcacct ctaaaatttg   1740

ggtgatgaca cagaggtata gattataaga tttaattatg aatgggtggt atactgtgaa   1800


<210>  9936
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9936

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9937
<211>  440
<212>  DNA
<213>  Homo sapiens

<400>  9937
cgaccttatg ttaatgaaaa acgagagaaa aatagccatt tatttgattt ctttttggct     60

cttttcctcc taagatccct aaatgcttca tagtaagtat gtcagtcttt ctcactacaa    120

ctgtgttaga atactttgca ttaaaaattt agatcttctt acatggaaga ggtcaaatcc    180

agttatagca aaacaccttt actgcagagg ccatataacc aaaaagtcca aaggcccagc    240

ccagtggacc atttacttca gtgatgttca gtacaaaatt tcactgccat taaagacttt    300

ggaaagtccc ttttaagttg taacaggatt tgactattag tgtggatttc gataaccctt    360

ctttagttaa tgtaataaat gctctttgaa gctggaaata tactggtttc ttgcaccctt    420

gtagttttct ctgggctttt                                                440


<210>  9938
<211>  77
<212>  PRT
<213>  Homo sapiens

<400>  9938

Met Leu His Ser Lys Tyr Val Ser Leu Ser His Tyr Asn Cys Val Arg 
1               5                   10                  15


Ile Leu Cys Ile Lys Asn Leu Asp Leu Leu Thr Trp Lys Arg Ser Asn 
            20                  25                  30


Pro Val Ile Ala Lys His Leu Tyr Cys Arg Gly His Ile Thr Lys Lys 
        35                  40                  45


Ser Lys Gly Pro Ala Gln Trp Thr Ile Tyr Phe Ser Asp Val Gln Tyr 
    50                  55                  60


Lys Ile Ser Leu Pro Leu Lys Thr Leu Glu Ser Pro Phe 
65                  70                  75


<210>  9939
<211>  884
<212>  DNA
<213>  Homo sapiens

<400>  9939
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaagggcgag atgtgtgaca gaggtggcat    420

caagctctta cagtcccaac cctccaacgg aaatgggcga agatctcagg aatggcatcg    480

gtcacaggaa atcgatagtg gctggctgct agcatggcca cttggggctt aggcagaaat    540

agagccatgg atgagaacaa gttgagcagt gccaacggcc atgaagaacg tagcaaaaaa    600

atactttgca ttaaaaattt agatcttctt acatggaaga ggtcaaatcc agttatagca    660

aaacaccttt actgcagagg ccatataacc aaaaagtcca aaggcccagc ccagtggacc    720

atttacttca gtgatgttca gtacaaaatt tcactgccat taaagacttt ggaaagtccc    780

ttttaagttg taacaggatt tgactattag tgtggatttc gataaccctt ctttagttaa    840

tgtaataaat gctctttgaa gctggaaata tactggtttc ttgc                     884


<210>  9940
<211>  90
<212>  PRT
<213>  Homo sapiens

<400>  9940

Met Ala Thr Trp Gly Leu Gly Arg Asn Arg Ala Met Asp Glu Asn Lys 
1               5                   10                  15


Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser Lys Lys Ile Leu Cys 
            20                  25                  30


Ile Lys Asn Leu Asp Leu Leu Thr Trp Lys Arg Ser Asn Pro Val Ile 
        35                  40                  45


Ala Lys His Leu Tyr Cys Arg Gly His Ile Thr Lys Lys Ser Lys Gly 
    50                  55                  60


Pro Ala Gln Trp Thr Ile Tyr Phe Ser Asp Val Gln Tyr Lys Ile Ser 
65                  70                  75                  80


Leu Pro Leu Lys Thr Leu Glu Ser Pro Phe 
                85                  90


<210>  9941
<211>  1059
<212>  DNA
<213>  Homo sapiens

<400>  9941
ttgtaatgct tagactcttg aagagctact ttctgtttta atgttaagat tcttgtgtct     60

tagttttttt taacatggat gtaattccat gtaaacaggt atggaagtag gaaatgttta    120

ggctggactt ggtggattat taattgactt tcttgggttc ttgggagtca acattactaa    180

agcagtgtga atccctgttt gcttcagggc gagatgtgtg acagaggtgg catcaagctc    240

ttacagtccc aaccctccaa cggaaatggg cgaagatctc aggaatggca tcggtcacag    300

gaaatcgata gtggctggct gctagcatgg ccacttgggg cttaggcaga aatagagcca    360

tggtactgac caaagggacc atagcacatg gaataaaact caaaacagga cttcatgttt    420

tatggaaatt atatttaacc acttcaacat tgtaaatctg gataactttt aatatctaaa    480

ctatataaga aagtaaaatt taacatgtta atatggaaaa tttttttatt tttgtatctt    540

gatgacttaa atgtaagcaa caaagtggtt aaacacatac ccatctaaat ttttttatag    600

ccttccatgt taaactataa gtaaataatt agttttaaaa ttgttttgta ttttcttatt    660

cctgttccct ttaccctttg acaacttgaa atgttaccac ttcgtcctca tgatgttctt    720

ctatcaaccc tgcttaggat gagaacaagt tgagcagtgc caacggccat gaagaacgta    780

gcaaaaaaat actttgcatt aaaaatttag atcttcttac atggaagagg tcaaatccag    840

ttatagcaaa acacctttac tgcagaggcc atataaccaa aaagtccaaa ggcccagccc    900

agtggaccat ttacttcagt gatgttcagt acaaaatttc actgccatta aagactttgg    960

aaagtccctt ttaagttgta acaggatttg actattagtg tggatttcga taacccttct   1020

ttagttaatg taataaatgc tctttgaagc tggaaatat                          1059


<210>  9942
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9942

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9943
<211>  716
<212>  DNA
<213>  Homo sapiens

<400>  9943
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa    420

cggccatgaa gaacgtagca aaaaaatact ttgcattaaa aatttagatc ttcttacatg    480

gaagaggtca aatccagtta tagcaaaaca cctttactgc agaggccata taaccaaaaa    540

gtccaaaggc ccagcccagt ggaccattta cttcagtgat gttcagtaca aaatttcact    600

gccattaaag actttggaaa gtccctttta agttgtaaca ggatttgact attagtgtgg    660

atttcgataa cccttcttta gttaatgtaa taaatgctct ttgaagctgg aaatat        716


<210>  9944
<211>  95
<212>  PRT
<213>  Homo sapiens

<400>  9944

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


Lys Lys Ile Leu Cys Ile Lys Asn Leu Asp Leu Leu Thr Trp Lys Arg 
        35                  40                  45


Ser Asn Pro Val Ile Ala Lys His Leu Tyr Cys Arg Gly His Ile Thr 
    50                  55                  60


Lys Lys Ser Lys Gly Pro Ala Gln Trp Thr Ile Tyr Phe Ser Asp Val 
65                  70                  75                  80


Gln Tyr Lys Ile Ser Leu Pro Leu Lys Thr Leu Glu Ser Pro Phe 
                85                  90                  95


<210>  9945
<211>  857
<212>  DNA
<213>  Homo sapiens

<400>  9945
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaaaatac tttgcattaa    600

aaatttagat cttcttacat ggaagaggtc aaatccagtt atagcaaaac acctttactg    660

cagaggccat ataaccaaaa agtccaaagg cccagcccag tggaccattt acttcagtga    720

tgttcagtac aaaatttcac tgccattaaa gactttggaa agtccctttt aagttgtaac    780

aggatttgac tattagtgtg gatttcgata acccttcttt agttaatgta ataaatgctc    840

tttgaagctg gaaatat                                                   857


<210>  9946
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9946

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9947
<211>  2764
<212>  DNA
<213>  Homo sapiens

<400>  9947
gcccggaaag aggcgctctc gttcgggtct cccagtttct gtttttggag ttgacagcag     60

agttttaaat attggatatt gaagtcttca ttttcgtgtg tttcgtgcgt ttagagaaaa    120

tggcagacga tattgatatt gaagcaatgc ttgaggctcc ttacaagaag gtgagaaaaa    180

acatgtcggt gaggtttata tatttcttaa tttagcatta ttcacgaaac tactgctgaa    240

atgtaaacta acctccccgg agccctcttg atttatctta tcagagatgc attacgtgta    300

acttacaaaa gtaaatatat gctattgatg taataatatt gtgcagtagt ttcacttcag    360

cgtgatgaat aaatgcccat ctatctctct ttgtagactt gcctaacgat atctcacctc    420

tactcccatg aattcacctt tgattccagt gtgaactgtc aatcataagg tagtaattga    480

gtgacttatc gctgtaccgt ggtcccctag gtaaaatgac tcaactaaga attaccacct    540

ccagtttggt atagcaaaaa ggtgaatgta gtggtttggg aaaaagcagg ggtccaagaa    600

taacaaagca tgaccagtct gtggcaagtt aaatcttcta acagtcttat aagaagaaat    660

gggtgagatt ttaaaattta tgtatctatg taagactggt gatagtaaat cttaaaacag    720

tccagtggca atctgctgct cagttaataa ttactaaaat tcttggatcc ctgaatagaa    780

attaaaaaaa aaaaatacaa gaggcagtag agtcaataca agcttaatac aagcttagag    840

taaatacaag cttagagtca cttgatgact gttttactgt tctccatatt gtttttattt    900

ttaattaggc cctaccatag tatttcacac taaaaacaaa ggaattatat tggctaatat    960

agtctttgac tcatttcggt atctcagtaa aagtaaactg tcttttcatt gtttcaccag   1020

ttggtggtga aaatagcagt atgcatgcat tatcactggt gtcacaaact gtaagctttg   1080

taagttagca ctttactcct atagctgatg taatcaaact ttaaaataaa catttcacta   1140

aaccttttaa aaataataca tttgttttgg attgtatagc acgaccatgt ggtaccaatt   1200

tggatgaatt cttgatagat ttaaatagtg tatgtaattt tgtaatgctt agactcttga   1260

agagctactt tctgttttaa tgttaagatt cttgtgtctt agtttttttt aacatggatg   1320

taattccatg taaacaggta tggaagtagg aaatgtttag gctggacttg gtggattatt   1380

aattgacttt cttgggttct tgggagtcaa cattactaaa gcagtgtgaa tccctgtttg   1440

cttcagggcg agatgtgtga cagaggtggc atcaagctct tacagtccca accctccaac   1500

ggaaatgggc gaagatctca ggaatggcat cggtcacagg aaatcgatag tggctggctg   1560

ctagcatggc cacttggggc ttaggcagaa atagagccat ggtactgacc aaagggacca   1620

tagcacatgg aataaaactc aaaacaggac ttcatgtttt atggaaatta tatttaacca   1680

cttcaacatt gtaaatctgg ataactttta atatctaaac tatataagaa agtaaaattt   1740

aacatgttaa tatggaaaat ttttttattt ttgtatcttg atgacttaaa tgtaagcaac   1800

aaagtggtta aacacatacc catctaaatt tttttatagc cttccatgtt aaactataag   1860

taaataatta gttttaaaat tgttttgtat tttcttattc ctgttccctt taccctttga   1920

caacttgaaa tgttaccact tcgtcctcat gatgttcttc tatcaaccct gcttaggatg   1980

agaacaagtt gagcagtgcc aacggccatg aagaacgtag caaaaagtga gttttaagaa   2040

ggggcttggg ggagggtggt gagctttttt gtggttttag accttaagtt gtgttcctgt   2100

ggctaaagta tacaaaattc tcttctgaag cttttctttg ctgcttttag aaaattggtt   2160

ctttgccttt tgagacaaac tcttggagga actgtggatt tttttgctta gatttcagaa   2220

tatagtttca gataccttcc cctccaagtc catcatgaca atctggtgac aagttctgta   2280

ttagaggttg tcttgtttta aatttgttaa ctttggtttg atatttggtt atcttactga   2340

taaaactgtt atatatccat tgatcttaaa aggtagaaag agttaaatta ggtgataact   2400

aggccatgga aagtattgtt tgccctaaag tgccgaagga gtcaaagctg tgaattattt   2460

ctgcaacttg ctgctcagag gcccttttgg aagtgatgga acaggtactt aagtacttct   2520

aaaggtggct ttcattatct taggcctttt aaactctaga cttaacaggg tggggatttt   2580

ggaaattatg aatatatctg tacactttat ttgggtaaga tgagtgactc aatagaactc   2640

tgctatagac tagtacagaa aacagtgtac gaaaagtctt aggtaacaga tatgatgaga   2700

tccacttttt ttttttcttt tcttgtgagt cggagtcttg ctctgtagcc caggctggag   2760

cgca                                                                2764


<210>  9948
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9948

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9949
<211>  2547
<212>  DNA
<213>  Homo sapiens

<400>  9949
cgggtttttg cccggaaaga ggcgctctcg ttcgggtctc ccagtttctg tttttggagt     60

tgacagcaga gttttaaata ttggatattg aagtcttcat tttcgtgtgt ttcgtgcgtt    120

tagagaaaat ggcagacgat attgatattg aagcaatgct tgaggctcct tacaagaaga    180

cttgcctaac gatatctcac ctctactccc atgaattcac ctttgattcc agtgtgaact    240

gtcaatcata aggtagtaat tgagtgactt atcgctgtac cgtggtcccc taggtaaaat    300

gactcaacta agaattacca cctccagttt ggtatagcaa aaaggtgaat gtagtggttt    360

gggaaaaagc aggggtccaa gaataacaaa gcatgaccag tctgtggcaa gttaaatctt    420

ctaacagtct tataagaaga aatgggtgag attttaaaat ttatgtatct atgtaagact    480

ggtgatagta aatcttaaaa cagtccagtg gcaatctgct gctcagttaa taattactaa    540

aattcttgga tccctgaata gaaattaaaa aaaaaaaata caagaggcag tagagtcaat    600

acaagcttaa tacaagctta gagtaaatac aagcttagag tcacttgatg actgttttac    660

tgttctccat attgttttta tttttaatta ggccctacca tagtatttca cactaaaaac    720

aaaggaatta tattggctaa tatagtcttt gactcatttc ggtatctcag taaaagtaaa    780

ctgtcttttc attgtttcac cagttggtgg tgaaaatagc agtatgcatg cattatcact    840

ggtgtcacaa actgtaagct ttgtaagtta gcactttact cctatagctg atgtaatcaa    900

actttaaaat aaacatttca ctaaaccttt taaaaataat acatttgttt tggattgtat    960

agcacgacca tgtggtacca atttggatga attcttgata gatttaaata gtgtatgtaa   1020

ttttgtaatg cttagactct tgaagagcta ctttctgttt taatgttaag attcttgtgt   1080

cttagttttt tttaacatgg atgtaattcc atgtaaacag gtatggaagt aggaaatgtt   1140

taggctggac ttggtggatt attaattgac tttcttgggt tcttgggagt caacattact   1200

aaagcagtgt gaatccctgt ttgcttcagg gcgagatgtg tgacagaggt ggcatcaagc   1260

tcttacagtc ccaaccctcc aacggaaatg ggcgaagatc tcaggaatgg catcggtcac   1320

aggaaatcga tagtggctgg ctgctagcat ggccacttgg ggcttaggca gaaatagagc   1380

catggtactg accaaaggga ccatagcaca tggaataaaa ctcaaaacag gacttcatgt   1440

tttatggaaa ttatatttaa ccacttcaac attgtaaatc tggataactt ttaatatcta   1500

aactatataa gaaagtaaaa tttaacatgt taatatggaa aattttttta tttttgtatc   1560

ttgatgactt aaatgtaagc aacaaagtgg ttaaacacat acccatctaa atttttttat   1620

agccttccat gttaaactat aagtaaataa ttagttttaa aattgttttg tattttctta   1680

ttcctgttcc ctttaccctt tgacaacttg aaatgttacc acttcgtcct catgatgttc   1740

ttctatcaac cctgcttagg atgagaacaa gttgagcagt gccaacggcc atgaagaacg   1800

tagcaaaaag tgagttttaa gaaggggctt gggggagggt ggtgagcttt tttgtggttt   1860

tagaccttaa gttgtgttcc tgtggctaaa gtatacaaaa ttctcttctg aagcttttct   1920

ttgctgcttt tagaaaattg gttctttgcc ttttgagaca aactcttgga ggaactgtgg   1980

atttttttgc ttagatttca gaatatagtt tcagatacct tcccctccaa gtccatcatg   2040

acaatctggt gacaagttct gtattagagg ttgtcttgtt ttaaatttgt taactttggt   2100

ttgatatttg gttatcttac tgataaaact gttatatatc cattgatctt aaaaggtaga   2160

aagagttaaa ttaggtgata actaggccat ggaaagtatt gtttgcccta aagtgccgaa   2220

ggagtcaaag ctgtgaatta tttctgcaac ttgctgctca gaggcccttt tggaagtgat   2280

ggaacaggta cttaagtact tctaaaggtg gctttcatta tcttaggcct tttaaactct   2340

agacttaaca gggtggggat tttggaaatt atgaatatat ctgtacactt tatttgggta   2400

agatgagtga ctcaatagaa ctctgctata gactagtaca gaaaacagtg tacgaaaagt   2460

cttaggtaac agatatgatg agatccactt tttttttttc ttttcttgtg agtcggagtc   2520

ttgctctgta gcccaggctg gagcgca                                       2547


<210>  9950
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9950

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9951
<211>  2661
<212>  DNA
<213>  Homo sapiens

<400>  9951
tgtgtgctgg tgaatgtgag tacagggaag cagcggccgc catttcaggg agcttgtcga     60

cgctgtcgca ggggtggatc ctgagctgcc gaagccgccg tcctgctctc ccgcctgggc    120

ctaggggctt aacagtagca acagaagcgg cggcggcggc agcagcagca gcagcagcag    180

caatctcttc ccgaacacga gcaccacagg cgcccgaagg ccggaacagg cgtttagaga    240

aaatggcaga cgatattgat attgaagcaa tgcttgaggc tccttacaag aagacttgcc    300

taacgatatc tcacctctac tcccatgaat tcacctttga ttccagtgtg aactgtcaat    360

cataaggtag taattgagtg acttatcgct gtaccgtggt cccctaggta aaatgactca    420

actaagaatt accacctcca gtttggtata gcaaaaaggt gaatgtagtg gtttgggaaa    480

aagcaggggt ccaagaataa caaagcatga ccagtctgtg gcaagttaaa tcttctaaca    540

gtcttataag aagaaatggg tgagatttta aaatttatgt atctatgtaa gactggtgat    600

agtaaatctt aaaacagtcc agtggcaatc tgctgctcag ttaataatta ctaaaattct    660

tggatccctg aatagaaatt aaaaaaaaaa aatacaagag gcagtagagt caatacaagc    720

ttaatacaag cttagagtaa atacaagctt agagtcactt gatgactgtt ttactgttct    780

ccatattgtt tttattttta attaggccct accatagtat ttcacactaa aaacaaagga    840

attatattgg ctaatatagt ctttgactca tttcggtatc tcagtaaaag taaactgtct    900

tttcattgtt tcaccagttg gtggtgaaaa tagcagtatg catgcattat cactggtgtc    960

acaaactgta agctttgtaa gttagcactt tactcctata gctgatgtaa tcaaacttta   1020

aaataaacat ttcactaaac cttttaaaaa taatacattt gttttggatt gtatagcacg   1080

accatgtggt accaatttgg atgaattctt gatagattta aatagtgtat gtaattttgt   1140

aatgcttaga ctcttgaaga gctactttct gttttaatgt taagattctt gtgtcttagt   1200

tttttttaac atggatgtaa ttccatgtaa acaggtatgg aagtaggaaa tgtttaggct   1260

ggacttggtg gattattaat tgactttctt gggttcttgg gagtcaacat tactaaagca   1320

gtgtgaatcc ctgtttgctt cagggcgaga tgtgtgacag aggtggcatc aagctcttac   1380

agtcccaacc ctccaacgga aatgggcgaa gatctcagga atggcatcgg tcacaggaaa   1440

tcgatagtgg ctggctgcta gcatggccac ttggggctta ggcagaaata gagccatggt   1500

actgaccaaa gggaccatag cacatggaat aaaactcaaa acaggacttc atgttttatg   1560

gaaattatat ttaaccactt caacattgta aatctggata acttttaata tctaaactat   1620

ataagaaagt aaaatttaac atgttaatat ggaaaatttt tttatttttg tatcttgatg   1680

acttaaatgt aagcaacaaa gtggttaaac acatacccat ctaaattttt ttatagcctt   1740

ccatgttaaa ctataagtaa ataattagtt ttaaaattgt tttgtatttt cttattcctg   1800

ttccctttac cctttgacaa cttgaaatgt taccacttcg tcctcatgat gttcttctat   1860

caaccctgct taggatgaga acaagttgag cagtgccaac ggccatgaag aacgtagcaa   1920

aaagtgagtt ttaagaaggg gcttggggga gggtggtgag cttttttgtg gttttagacc   1980

ttaagttgtg ttcctgtggc taaagtatac aaaattctct tctgaagctt ttctttgctg   2040

cttttagaaa attggttctt tgccttttga gacaaactct tggaggaact gtggattttt   2100

ttgcttagat ttcagaatat agtttcagat accttcccct ccaagtccat catgacaatc   2160

tggtgacaag ttctgtatta gaggttgtct tgttttaaat ttgttaactt tggtttgata   2220

tttggttatc ttactgataa aactgttata tatccattga tcttaaaagg tagaaagagt   2280

taaattaggt gataactagg ccatggaaag tattgtttgc cctaaagtgc cgaaggagtc   2340

aaagctgtga attatttctg caacttgctg ctcagaggcc cttttggaag tgatggaaca   2400

ggtacttaag tacttctaaa ggtggctttc attatcttag gccttttaaa ctctagactt   2460

aacagggtgg ggattttgga aattatgaat atatctgtac actttatttg ggtaagatga   2520

gtgactcaat agaactctgc tatagactag tacagaaaac agtgtacgaa aagtcttagg   2580

taacagatat gatgagatcc actttttttt tttcttttct tgtgagtcgg agtcttgctc   2640

tgtagcccag gctggagcgc a                                             2661


<210>  9952
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9952

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9953
<211>  2888
<212>  DNA
<213>  Homo sapiens

<400>  9953
atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg gagcttgtcg     60

acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct cccgcctggg    120

cctaggggct taacagtagc aacagaagcg gcggcggcgg cagcagcagc agcagcagca    180

gcaatctctt cccgaacacg agcaccacag gcgcccgaag gccggaacag gcgtttagag    240

aaaatggcag acgatattga tattgaagca atgcttgagg ctccttacaa gaaggtgaga    300

aaaaacatgt cggtgaggtt tatatatttc ttaatttagc attattcacg aaactactgc    360

tgaaatgtaa actaacctcc ccggagccct cttgatttat cttatcagag atgcattacg    420

tgtaacttac aaaagtaaat atatgctatt gatgtaataa tattgtgcag tagtttcact    480

tcagcgtgat gaataaatgc ccatctatct ctctttgtag acttgcctaa cgatatctca    540

cctctactcc catgaattca cctttgattc cagtgtgaac tgtcaatcat aaggtagtaa    600

ttgagtgact tatcgctgta ccgtggtccc ctaggtaaaa tgactcaact aagaattacc    660

acctccagtt tggtatagca aaaaggtgaa tgtagtggtt tgggaaaaag caggggtcca    720

agaataacaa agcatgacca gtctgtggca agttaaatct tctaacagtc ttataagaag    780

aaatgggtga gattttaaaa tttatgtatc tatgtaagac tggtgatagt aaatcttaaa    840

acagtccagt ggcaatctgc tgctcagtta ataattacta aaattcttgg atccctgaat    900

agaaattaaa aaaaaaaaat acaagaggca gtagagtcaa tacaagctta atacaagctt    960

agagtaaata caagcttaga gtcacttgat gactgtttta ctgttctcca tattgttttt   1020

atttttaatt aggccctacc atagtatttc acactaaaaa caaaggaatt atattggcta   1080

atatagtctt tgactcattt cggtatctca gtaaaagtaa actgtctttt cattgtttca   1140

ccagttggtg gtgaaaatag cagtatgcat gcattatcac tggtgtcaca aactgtaagc   1200

tttgtaagtt agcactttac tcctatagct gatgtaatca aactttaaaa taaacatttc   1260

actaaacctt ttaaaaataa tacatttgtt ttggattgta tagcacgacc atgtggtacc   1320

aatttggatg aattcttgat agatttaaat agtgtatgta attttgtaat gcttagactc   1380

ttgaagagct actttctgtt ttaatgttaa gattcttgtg tcttagtttt ttttaacatg   1440

gatgtaattc catgtaaaca ggtatggaag taggaaatgt ttaggctgga cttggtggat   1500

tattaattga ctttcttggg ttcttgggag tcaacattac taaagcagtg tgaatccctg   1560

tttgcttcag ggcgagatgt gtgacagagg tggcatcaag ctcttacagt cccaaccctc   1620

caacggaaat gggcgaagat ctcaggaatg gcatcggtca caggaaatcg atagtggctg   1680

gctgctagca tggccacttg gggcttaggc agaaatagag ccatggtact gaccaaaggg   1740

accatagcac atggaataaa actcaaaaca ggacttcatg ttttatggaa attatattta   1800

accacttcaa cattgtaaat ctggataact tttaatatct aaactatata agaaagtaaa   1860

atttaacatg ttaatatgga aaattttttt atttttgtat cttgatgact taaatgtaag   1920

caacaaagtg gttaaacaca tacccatcta aattttttta tagccttcca tgttaaacta   1980

taagtaaata attagtttta aaattgtttt gtattttctt attcctgttc cctttaccct   2040

ttgacaactt gaaatgttac cacttcgtcc tcatgatgtt cttctatcaa ccctgcttag   2100

gatgagaaca agttgagcag tgccaacggc catgaagaac gtagcaaaaa gtgagtttta   2160

agaaggggct tgggggaggg tggtgagctt ttttgtggtt ttagacctta agttgtgttc   2220

ctgtggctaa agtatacaaa attctcttct gaagcttttc tttgctgctt ttagaaaatt   2280

ggttctttgc cttttgagac aaactcttgg aggaactgtg gatttttttg cttagatttc   2340

agaatatagt ttcagatacc ttcccctcca agtccatcat gacaatctgg tgacaagttc   2400

tgtattagag gttgtcttgt tttaaatttg ttaactttgg tttgatattt ggttatctta   2460

ctgataaaac tgttatatat ccattgatct taaaaggtag aaagagttaa attaggtgat   2520

aactaggcca tggaaagtat tgtttgccct aaagtgccga aggagtcaaa gctgtgaatt   2580

atttctgcaa cttgctgctc agaggccctt ttggaagtga tggaacaggt acttaagtac   2640

ttctaaaggt ggctttcatt atcttaggcc ttttaaactc tagacttaac agggtgggga   2700

ttttggaaat tatgaatata tctgtacact ttatttgggt aagatgagtg actcaataga   2760

actctgctat agactagtac agaaaacagt gtacgaaaag tcttaggtaa cagatatgat   2820

gagatccact tttttttttt cttttcttgt gagtcggagt cttgctctgt agcccaggct   2880

ggagcgca                                                            2888


<210>  9954
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  9954

Met Cys Ala Gly Glu Cys Glu Tyr Arg Glu Ala Ala Ala Ala Ile Ser 
1               5                   10                  15


Gly Ser Leu Ser Thr Leu Ser Gln Gly Trp Ile Leu Ser Cys Arg Ser 
            20                  25                  30


Arg Arg Pro Ala Leu Pro Pro Gly Pro Arg Gly Leu Thr Val Ala Thr 
        35                  40                  45


Glu Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ile Ser Ser 
    50                  55                  60


Arg Thr Arg Ala Pro Gln Ala Pro Glu Gly Arg Asn Arg Arg Leu Glu 
65                  70                  75                  80


Lys Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr 
                85                  90                  95


Lys Lys Val Arg Lys Asn Met Ser Val Arg Phe Ile Tyr Phe Leu Ile 
            100                 105                 110


<210>  9955
<211>  2629
<212>  DNA
<213>  Homo sapiens

<400>  9955
gtgtgtgtat gtgtgctggt gaatattctc tcgggcctag ccgtccttgg aacccgatat     60

tcgggctggg cggttccgcg gcctgggcct aggggcttaa cagtagcaac agaagcggcg    120

gcggcggcag cagcagcagc agcagcagca atctcttccc gaacacgagc accacaggcg    180

cccgaaggcc ggaacaggcg tttagagaaa atggcagacg atattgatat tgaagcaatg    240

cttgaggctc cttacaagaa gacttgccta acgatatctc acctctactc ccatgaattc    300

acctttgatt ccagtgtgaa ctgtcaatca taaggtagta attgagtgac ttatcgctgt    360

accgtggtcc cctaggtaaa atgactcaac taagaattac cacctccagt ttggtatagc    420

aaaaaggtga atgtagtggt ttgggaaaaa gcaggggtcc aagaataaca aagcatgacc    480

agtctgtggc aagttaaatc ttctaacagt cttataagaa gaaatgggtg agattttaaa    540

atttatgtat ctatgtaaga ctggtgatag taaatcttaa aacagtccag tggcaatctg    600

ctgctcagtt aataattact aaaattcttg gatccctgaa tagaaattaa aaaaaaaaaa    660

tacaagaggc agtagagtca atacaagctt aatacaagct tagagtaaat acaagcttag    720

agtcacttga tgactgtttt actgttctcc atattgtttt tatttttaat taggccctac    780

catagtattt cacactaaaa acaaaggaat tatattggct aatatagtct ttgactcatt    840

tcggtatctc agtaaaagta aactgtcttt tcattgtttc accagttggt ggtgaaaata    900

gcagtatgca tgcattatca ctggtgtcac aaactgtaag ctttgtaagt tagcacttta    960

ctcctatagc tgatgtaatc aaactttaaa ataaacattt cactaaacct tttaaaaata   1020

atacatttgt tttggattgt atagcacgac catgtggtac caatttggat gaattcttga   1080

tagatttaaa tagtgtatgt aattttgtaa tgcttagact cttgaagagc tactttctgt   1140

tttaatgtta agattcttgt gtcttagttt tttttaacat ggatgtaatt ccatgtaaac   1200

aggtatggaa gtaggaaatg tttaggctgg acttggtgga ttattaattg actttcttgg   1260

gttcttggga gtcaacatta ctaaagcagt gtgaatccct gtttgcttca gggcgagatg   1320

tgtgacagag gtggcatcaa gctcttacag tcccaaccct ccaacggaaa tgggcgaaga   1380

tctcaggaat ggcatcggtc acaggaaatc gatagtggct ggctgctagc atggccactt   1440

ggggcttagg cagaaataga gccatggtac tgaccaaagg gaccatagca catggaataa   1500

aactcaaaac aggacttcat gttttatgga aattatattt aaccacttca acattgtaaa   1560

tctggataac ttttaatatc taaactatat aagaaagtaa aatttaacat gttaatatgg   1620

aaaatttttt tatttttgta tcttgatgac ttaaatgtaa gcaacaaagt ggttaaacac   1680

atacccatct aaattttttt atagccttcc atgttaaact ataagtaaat aattagtttt   1740

aaaattgttt tgtattttct tattcctgtt ccctttaccc tttgacaact tgaaatgtta   1800

ccacttcgtc ctcatgatgt tcttctatca accctgctta ggatgagaac aagttgagca   1860

gtgccaacgg ccatgaagaa cgtagcaaaa agtgagtttt aagaaggggc ttgggggagg   1920

gtggtgagct tttttgtggt tttagacctt aagttgtgtt cctgtggcta aagtatacaa   1980

aattctcttc tgaagctttt ctttgctgct tttagaaaat tggttctttg ccttttgaga   2040

caaactcttg gaggaactgt ggattttttt gcttagattt cagaatatag tttcagatac   2100

cttcccctcc aagtccatca tgacaatctg gtgacaagtt ctgtattaga ggttgtcttg   2160

ttttaaattt gttaactttg gtttgatatt tggttatctt actgataaaa ctgttatata   2220

tccattgatc ttaaaaggta gaaagagtta aattaggtga taactaggcc atggaaagta   2280

ttgtttgccc taaagtgccg aaggagtcaa agctgtgaat tatttctgca acttgctgct   2340

cagaggccct tttggaagtg atggaacagg tacttaagta cttctaaagg tggctttcat   2400

tatcttaggc cttttaaact ctagacttaa cagggtgggg attttggaaa ttatgaatat   2460

atctgtacac tttatttggg taagatgagt gactcaatag aactctgcta tagactagta   2520

cagaaaacag tgtacgaaaa gtcttaggta acagatatga tgagatccac tttttttttt   2580

tcttttcttg tgagtcggag tcttgctctg tagcccaggc tggagcgca               2629


<210>  9956
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9956

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9957
<211>  2857
<212>  DNA
<213>  Homo sapiens

<400>  9957
gtgtgtgtgt atgtgtgctg gtgaatattc tctcgggcct agccgtcctt ggaacccgat     60

attcgggctg ggcggttccg cggcctgggc ctaggggctt aacagtagca acagaagcgg    120

cggcggcggc agcagcagca gcagcagcag caatctcttc ccgaacacga gcaccacagg    180

cgcccgaagg ccggaacagg cgtttagaga aaatggcaga cgatattgat attgaagcaa    240

tgcttgaggc tccttacaag aaggtgagaa aaaacatgtc ggtgaggttt atatatttct    300

taatttagca ttattcacga aactactgct gaaatgtaaa ctaacctccc cggagccctc    360

ttgatttatc ttatcagaga tgcattacgt gtaacttaca aaagtaaata tatgctattg    420

atgtaataat attgtgcagt agtttcactt cagcgtgatg aataaatgcc catctatctc    480

tctttgtaga cttgcctaac gatatctcac ctctactccc atgaattcac ctttgattcc    540

agtgtgaact gtcaatcata aggtagtaat tgagtgactt atcgctgtac cgtggtcccc    600

taggtaaaat gactcaacta agaattacca cctccagttt ggtatagcaa aaaggtgaat    660

gtagtggttt gggaaaaagc aggggtccaa gaataacaaa gcatgaccag tctgtggcaa    720

gttaaatctt ctaacagtct tataagaaga aatgggtgag attttaaaat ttatgtatct    780

atgtaagact ggtgatagta aatcttaaaa cagtccagtg gcaatctgct gctcagttaa    840

taattactaa aattcttgga tccctgaata gaaattaaaa aaaaaaaata caagaggcag    900

tagagtcaat acaagcttaa tacaagctta gagtaaatac aagcttagag tcacttgatg    960

actgttttac tgttctccat attgttttta tttttaatta ggccctacca tagtatttca   1020

cactaaaaac aaaggaatta tattggctaa tatagtcttt gactcatttc ggtatctcag   1080

taaaagtaaa ctgtcttttc attgtttcac cagttggtgg tgaaaatagc agtatgcatg   1140

cattatcact ggtgtcacaa actgtaagct ttgtaagtta gcactttact cctatagctg   1200

atgtaatcaa actttaaaat aaacatttca ctaaaccttt taaaaataat acatttgttt   1260

tggattgtat agcacgacca tgtggtacca atttggatga attcttgata gatttaaata   1320

gtgtatgtaa ttttgtaatg cttagactct tgaagagcta ctttctgttt taatgttaag   1380

attcttgtgt cttagttttt tttaacatgg atgtaattcc atgtaaacag gtatggaagt   1440

aggaaatgtt taggctggac ttggtggatt attaattgac tttcttgggt tcttgggagt   1500

caacattact aaagcagtgt gaatccctgt ttgcttcagg gcgagatgtg tgacagaggt   1560

ggcatcaagc tcttacagtc ccaaccctcc aacggaaatg ggcgaagatc tcaggaatgg   1620

catcggtcac aggaaatcga tagtggctgg ctgctagcat ggccacttgg ggcttaggca   1680

gaaatagagc catggtactg accaaaggga ccatagcaca tggaataaaa ctcaaaacag   1740

gacttcatgt tttatggaaa ttatatttaa ccacttcaac attgtaaatc tggataactt   1800

ttaatatcta aactatataa gaaagtaaaa tttaacatgt taatatggaa aattttttta   1860

tttttgtatc ttgatgactt aaatgtaagc aacaaagtgg ttaaacacat acccatctaa   1920

atttttttat agccttccat gttaaactat aagtaaataa ttagttttaa aattgttttg   1980

tattttctta ttcctgttcc ctttaccctt tgacaacttg aaatgttacc acttcgtcct   2040

catgatgttc ttctatcaac cctgcttagg atgagaacaa gttgagcagt gccaacggcc   2100

atgaagaacg tagcaaaaag tgagttttaa gaaggggctt gggggagggt ggtgagcttt   2160

tttgtggttt tagaccttaa gttgtgttcc tgtggctaaa gtatacaaaa ttctcttctg   2220

aagcttttct ttgctgcttt tagaaaattg gttctttgcc ttttgagaca aactcttgga   2280

ggaactgtgg atttttttgc ttagatttca gaatatagtt tcagatacct tcccctccaa   2340

gtccatcatg acaatctggt gacaagttct gtattagagg ttgtcttgtt ttaaatttgt   2400

taactttggt ttgatatttg gttatcttac tgataaaact gttatatatc cattgatctt   2460

aaaaggtaga aagagttaaa ttaggtgata actaggccat ggaaagtatt gtttgcccta   2520

aagtgccgaa ggagtcaaag ctgtgaatta tttctgcaac ttgctgctca gaggcccttt   2580

tggaagtgat ggaacaggta cttaagtact tctaaaggtg gctttcatta tcttaggcct   2640

tttaaactct agacttaaca gggtggggat tttggaaatt atgaatatat ctgtacactt   2700

tatttgggta agatgagtga ctcaatagaa ctctgctata gactagtaca gaaaacagtg   2760

tacgaaaagt cttaggtaac agatatgatg agatccactt tttttttttc ttttcttgtg   2820

agtcggagtc ttgctctgta gcccaggctg gagcgca                            2857


<210>  9958
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9958

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9959
<211>  2794
<212>  DNA
<213>  Homo sapiens

<400>  9959
gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc tggtgaatgt     60

gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc gcaggggtgg    120

atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta attccattgt    180

tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg ctgggcggtt    240

ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc ggcagcagca    300

gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga aggccggaac    360

aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga ggctccttac    420

aagaagactt gcctaacgat atctcacctc tactcccatg aattcacctt tgattccagt    480

gtgaactgtc aatcataagg tagtaattga gtgacttatc gctgtaccgt ggtcccctag    540

gtaaaatgac tcaactaaga attaccacct ccagtttggt atagcaaaaa ggtgaatgta    600

gtggtttggg aaaaagcagg ggtccaagaa taacaaagca tgaccagtct gtggcaagtt    660

aaatcttcta acagtcttat aagaagaaat gggtgagatt ttaaaattta tgtatctatg    720

taagactggt gatagtaaat cttaaaacag tccagtggca atctgctgct cagttaataa    780

ttactaaaat tcttggatcc ctgaatagaa attaaaaaaa aaaaatacaa gaggcagtag    840

agtcaataca agcttaatac aagcttagag taaatacaag cttagagtca cttgatgact    900

gttttactgt tctccatatt gtttttattt ttaattaggc cctaccatag tatttcacac    960

taaaaacaaa ggaattatat tggctaatat agtctttgac tcatttcggt atctcagtaa   1020

aagtaaactg tcttttcatt gtttcaccag ttggtggtga aaatagcagt atgcatgcat   1080

tatcactggt gtcacaaact gtaagctttg taagttagca ctttactcct atagctgatg   1140

taatcaaact ttaaaataaa catttcacta aaccttttaa aaataataca tttgttttgg   1200

attgtatagc acgaccatgt ggtaccaatt tggatgaatt cttgatagat ttaaatagtg   1260

tatgtaattt tgtaatgctt agactcttga agagctactt tctgttttaa tgttaagatt   1320

cttgtgtctt agtttttttt aacatggatg taattccatg taaacaggta tggaagtagg   1380

aaatgtttag gctggacttg gtggattatt aattgacttt cttgggttct tgggagtcaa   1440

cattactaaa gcagtgtgaa tccctgtttg cttcagggcg agatgtgtga cagaggtggc   1500

atcaagctct tacagtccca accctccaac ggaaatgggc gaagatctca ggaatggcat   1560

cggtcacagg aaatcgatag tggctggctg ctagcatggc cacttggggc ttaggcagaa   1620

atagagccat ggtactgacc aaagggacca tagcacatgg aataaaactc aaaacaggac   1680

ttcatgtttt atggaaatta tatttaacca cttcaacatt gtaaatctgg ataactttta   1740

atatctaaac tatataagaa agtaaaattt aacatgttaa tatggaaaat ttttttattt   1800

ttgtatcttg atgacttaaa tgtaagcaac aaagtggtta aacacatacc catctaaatt   1860

tttttatagc cttccatgtt aaactataag taaataatta gttttaaaat tgttttgtat   1920

tttcttattc ctgttccctt taccctttga caacttgaaa tgttaccact tcgtcctcat   1980

gatgttcttc tatcaaccct gcttaggatg agaacaagtt gagcagtgcc aacggccatg   2040

aagaacgtag caaaaagtga gttttaagaa ggggcttggg ggagggtggt gagctttttt   2100

gtggttttag accttaagtt gtgttcctgt ggctaaagta tacaaaattc tcttctgaag   2160

cttttctttg ctgcttttag aaaattggtt ctttgccttt tgagacaaac tcttggagga   2220

actgtggatt tttttgctta gatttcagaa tatagtttca gataccttcc cctccaagtc   2280

catcatgaca atctggtgac aagttctgta ttagaggttg tcttgtttta aatttgttaa   2340

ctttggtttg atatttggtt atcttactga taaaactgtt atatatccat tgatcttaaa   2400

aggtagaaag agttaaatta ggtgataact aggccatgga aagtattgtt tgccctaaag   2460

tgccgaagga gtcaaagctg tgaattattt ctgcaacttg ctgctcagag gcccttttgg   2520

aagtgatgga acaggtactt aagtacttct aaaggtggct ttcattatct taggcctttt   2580

aaactctaga cttaacaggg tggggatttt ggaaattatg aatatatctg tacactttat   2640

ttgggtaaga tgagtgactc aatagaactc tgctatagac tagtacagaa aacagtgtac   2700

gaaaagtctt aggtaacaga tatgatgaga tccacttttt ttttttcttt tcttgtgagt   2760

cggagtcttg ctctgtagcc caggctggag cgca                               2794


<210>  9960
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9960

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9961
<211>  1853
<212>  DNA
<213>  Homo sapiens

<400>  9961
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataagggcga    540

gatgtgtgac agaggtggca tcaagctctt acagtcccaa ccctccaacg gaaatgggcg    600

aagatctcag gaatggcatc ggtcacagga aatcgatagt ggctggctgc tagcatggcc    660

acttggggct taggcagaaa tagagccatg gtactgacca aagggaccat agcacatgga    720

ataaaactca aaacaggact tcatgtttta tggaaattat atttaaccac ttcaacattg    780

taaatctgga taacttttaa tatctaaact atataagaaa gtaaaattta acatgttaat    840

atggaaaatt tttttatttt tgtatcttga tgacttaaat gtaagcaaca aagtggttaa    900

acacataccc atctaaattt ttttatagcc ttccatgtta aactataagt aaataattag    960

ttttaaaatt gttttgtatt ttcttattcc tgttcccttt accctttgac aacttgaaat   1020

gttaccactt cgtcctcatg atgttcttct atcaaccctg cttaggatga gaacaagttg   1080

agcagtgcca acggccatga agaacgtagc aaaaagtgag ttttaagaag gggcttgggg   1140

gagggtggtg agcttttttg tggttttaga ccttaagttg tgttcctgtg gctaaagtat   1200

acaaaattct cttctgaagc ttttctttgc tgcttttaga aaattggttc tttgcctttt   1260

gagacaaact cttggaggaa ctgtggattt ttttgcttag atttcagaat atagtttcag   1320

ataccttccc ctccaagtcc atcatgacaa tctggtgaca agttctgtat tagaggttgt   1380

cttgttttaa atttgttaac tttggtttga tatttggtta tcttactgat aaaactgtta   1440

tatatccatt gatcttaaaa ggtagaaaga gttaaattag gtgataacta ggccatggaa   1500

agtattgttt gccctaaagt gccgaaggag tcaaagctgt gaattatttc tgcaacttgc   1560

tgctcagagg cccttttgga agtgatggaa caggtactta agtacttcta aaggtggctt   1620

tcattatctt aggcctttta aactctagac ttaacagggt ggggattttg gaaattatga   1680

atatatctgt acactttatt tgggtaagat gagtgactca atagaactct gctatagact   1740

agtacagaaa acagtgtacg aaaagtctta ggtaacagat atgatgagat ccactttttt   1800

tttttctttt cttgtgagtc ggagtcttgc tctgtagccc aggctggagc gca          1853


<210>  9962
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9962

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9963
<211>  586
<212>  DNA
<213>  Homo sapiens

<400>  9963
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc aaaaag                   586


<210>  9964
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9964

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9965
<211>  444
<212>  DNA
<213>  Homo sapiens

<400>  9965
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa    420

cggccatgaa gaacgtagca aaaa                                           444


<210>  9966
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  9966

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg Ser 
            20                  25                  30


<210>  9967
<211>  547
<212>  DNA
<213>  Homo sapiens

<400>  9967
gtgtttgtgt gtgtgtatgt gtgctggtga atattctctc gggcctagcc gtccttggaa     60

cccgatattc gggctgggcg gttccgcggc ctgggcctag gggcttaaca gtagcaacag    120

aagcggcggc ggcggcagca gcagcagcag cagcagcaat ctcttcccga acacgagcac    180

cacaggcgcc cgaaggccgg aacaggcgtt tagagaaaat ggcagacgat attgatattg    240

aagcaatgct tgaggctcct tacaagaaga cttgcctaac gatatctcac ctctactccc    300

atgaattcac ctttgattcc agtgtgaact gtcaatcata agggcgagat gtgtgacaga    360

ggtggcatca agctcttaca gtcccaaccc tccaacggaa atgggcgaag atctcaggaa    420

tggcatcggt cacaggaaat cgatagtggc tggctgctag catggccact tggggcttag    480

gcagaaatag agccatggat gagaacaagt tgagcagtgc caacggccat gaagaacgta    540

gcaaaaa                                                              547


<210>  9968
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9968

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9969
<211>  2021
<212>  DNA
<213>  Homo sapiens

<400>  9969
gcccggaaag aggcgctctc gttcgggtct cccagtttct gtttttggag ttgacagcag     60

agttttaaat attggatatt gaagtcttca ttttcgtgtg tttcgtgcgt ttagagaaaa    120

tggcagacga tattgatatt gaagcaatgc ttgaggctcc ttacaagaag gtgagaaaaa    180

acatgtcggt gaggtttata tatttcttaa tttagcatta ttcacgaaac tactgctgaa    240

atgtaaacta acctccccgg agccctcttg atttatctta tcagagatgc attacgtgta    300

acttacaaaa gtaaatatat gctattgatg taataatatt gtgcagtagt ttcacttcag    360

cgtgatgaat aaatgcccat ctatctctct ttgtagactt gcctaacgat atctcacctc    420

tactcccatg aattcacctt tgattccagt gtgaactgtc aatcataagg tagtaattga    480

gtgacttatc gctgtaccgt ggtcccctag gtaaaatgac tcaactaaga attaccacct    540

ccagtttggt atagcaaaaa ggtgaatgta gtggtttggg aaaaagcagg ggtccaagaa    600

taacaaagca tgaccagtct gtggcaagtt aaatcttcta acagtcttat aagaagaaat    660

gggtgagatt ttaaaattta tgtatctatg taagactggt gatagtaaat cttaaaacag    720

tccagtggca atctgctgct cagttaataa ttactaaaat tcttggatcc ctgaatagaa    780

attaaaaaaa aaaaatacaa gaggcagtag agtcaataca agcttaatac aagcttagag    840

taaatacaag cttagagtca cttgatgact gttttactgt tctccatatt gtttttattt    900

ttaattaggc cctaccatag tatttcacac taaaaacaaa ggaattatat tggctaatat    960

agtctttgac tcatttcggt atctcagtaa aagtaaactg tcttttcatt gtttcaccag   1020

ttggtggtga aaatagcagt atgcatgcat tatcactggt gtcacaaact gtaagctttg   1080

taagttagca ctttactcct atagctgatg taatcaaact ttaaaataaa catttcacta   1140

aaccttttaa aaataataca tttgttttgg attgtatagc acgaccatgt ggtaccaatt   1200

tggatgaatt cttgatagat ttaaatagtg tatgtaattt tgtaatgctt agactcttga   1260

agagctactt tctgttttaa tgttaagatt cttgtgtctt agtttttttt aacatggatg   1320

taattccatg taaacaggta tggaagtagg aaatgtttag gctggacttg gtggattatt   1380

aattgacttt cttgggttct tgggagtcaa cattactaaa gcagtgtgaa tccctgtttg   1440

cttcagggcg agatgtgtga cagaggtggc atcaagctct tacagtccca accctccaac   1500

ggaaatgggc gaagatctca ggaatggcat cggtcacagg aaatcgatag tggctggctg   1560

ctagcatggc cacttggggc ttaggcagaa atagagccat ggtactgacc aaagggacca   1620

tagcacatgg aataaaactc aaaacaggac ttcatgtttt atggaaatta tatttaacca   1680

cttcaacatt gtaaatctgg ataactttta atatctaaac tatataagaa agtaaaattt   1740

aacatgttaa tatggaaaat ttttttattt ttgtatcttg atgacttaaa tgtaagcaac   1800

aaagtggtta aacacatacc catctaaatt tttttatagc cttccatgtt aaactataag   1860

taaataatta gttttaaaat tgttttgtat tttcttattc ctgttccctt taccctttga   1920

caacttgaaa tgttaccact tcgtcctcat gatgttcttc tatcaaccct gcttaggatg   1980

agaacaagtt gagcagtgcc aacggccatg aagaacgtag c                       2021


<210>  9970
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9970

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9971
<211>  1804
<212>  DNA
<213>  Homo sapiens

<400>  9971
cgggtttttg cccggaaaga ggcgctctcg ttcgggtctc ccagtttctg tttttggagt     60

tgacagcaga gttttaaata ttggatattg aagtcttcat tttcgtgtgt ttcgtgcgtt    120

tagagaaaat ggcagacgat attgatattg aagcaatgct tgaggctcct tacaagaaga    180

cttgcctaac gatatctcac ctctactccc atgaattcac ctttgattcc agtgtgaact    240

gtcaatcata aggtagtaat tgagtgactt atcgctgtac cgtggtcccc taggtaaaat    300

gactcaacta agaattacca cctccagttt ggtatagcaa aaaggtgaat gtagtggttt    360

gggaaaaagc aggggtccaa gaataacaaa gcatgaccag tctgtggcaa gttaaatctt    420

ctaacagtct tataagaaga aatgggtgag attttaaaat ttatgtatct atgtaagact    480

ggtgatagta aatcttaaaa cagtccagtg gcaatctgct gctcagttaa taattactaa    540

aattcttgga tccctgaata gaaattaaaa aaaaaaaata caagaggcag tagagtcaat    600

acaagcttaa tacaagctta gagtaaatac aagcttagag tcacttgatg actgttttac    660

tgttctccat attgttttta tttttaatta ggccctacca tagtatttca cactaaaaac    720

aaaggaatta tattggctaa tatagtcttt gactcatttc ggtatctcag taaaagtaaa    780

ctgtcttttc attgtttcac cagttggtgg tgaaaatagc agtatgcatg cattatcact    840

ggtgtcacaa actgtaagct ttgtaagtta gcactttact cctatagctg atgtaatcaa    900

actttaaaat aaacatttca ctaaaccttt taaaaataat acatttgttt tggattgtat    960

agcacgacca tgtggtacca atttggatga attcttgata gatttaaata gtgtatgtaa   1020

ttttgtaatg cttagactct tgaagagcta ctttctgttt taatgttaag attcttgtgt   1080

cttagttttt tttaacatgg atgtaattcc atgtaaacag gtatggaagt aggaaatgtt   1140

taggctggac ttggtggatt attaattgac tttcttgggt tcttgggagt caacattact   1200

aaagcagtgt gaatccctgt ttgcttcagg gcgagatgtg tgacagaggt ggcatcaagc   1260

tcttacagtc ccaaccctcc aacggaaatg ggcgaagatc tcaggaatgg catcggtcac   1320

aggaaatcga tagtggctgg ctgctagcat ggccacttgg ggcttaggca gaaatagagc   1380

catggtactg accaaaggga ccatagcaca tggaataaaa ctcaaaacag gacttcatgt   1440

tttatggaaa ttatatttaa ccacttcaac attgtaaatc tggataactt ttaatatcta   1500

aactatataa gaaagtaaaa tttaacatgt taatatggaa aattttttta tttttgtatc   1560

ttgatgactt aaatgtaagc aacaaagtgg ttaaacacat acccatctaa atttttttat   1620

agccttccat gttaaactat aagtaaataa ttagttttaa aattgttttg tattttctta   1680

ttcctgttcc ctttaccctt tgacaacttg aaatgttacc acttcgtcct catgatgttc   1740

ttctatcaac cctgcttagg atgagaacaa gttgagcagt gccaacggcc atgaagaacg   1800

tagc                                                                1804


<210>  9972
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9972

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9973
<211>  355
<212>  DNA
<213>  Homo sapiens

<400>  9973
attctctcgg gcctagccgt ccttggaacc cgatattcgg gctgggcggt tccgcggcct     60

gggcctaggg gcttaacagt agcaacagaa gcggcggcgg cggcagcagc agcagcagca    120

gcagcaatct cttcccgaac acgagcacca caggcgcccg aaggccggaa caggcgttta    180

gagaaaatgg cagacgatat tgatattgaa gcaatgcttg aggctcctta caagaagact    240

tgcctaacga tatctcacct ctactcccat gaattcacct ttgattccag tgtgaactgt    300

caatcataag gatgagaaca agttgagcag tgccaacggc catgaagaac gtagc         355


<210>  9974
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9974

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9975
<211>  1918
<212>  DNA
<213>  Homo sapiens

<400>  9975
tgtgtgctgg tgaatgtgag tacagggaag cagcggccgc catttcaggg agcttgtcga     60

cgctgtcgca ggggtggatc ctgagctgcc gaagccgccg tcctgctctc ccgcctgggc    120

ctaggggctt aacagtagca acagaagcgg cggcggcggc agcagcagca gcagcagcag    180

caatctcttc ccgaacacga gcaccacagg cgcccgaagg ccggaacagg cgtttagaga    240

aaatggcaga cgatattgat attgaagcaa tgcttgaggc tccttacaag aagacttgcc    300

taacgatatc tcacctctac tcccatgaat tcacctttga ttccagtgtg aactgtcaat    360

cataaggtag taattgagtg acttatcgct gtaccgtggt cccctaggta aaatgactca    420

actaagaatt accacctcca gtttggtata gcaaaaaggt gaatgtagtg gtttgggaaa    480

aagcaggggt ccaagaataa caaagcatga ccagtctgtg gcaagttaaa tcttctaaca    540

gtcttataag aagaaatggg tgagatttta aaatttatgt atctatgtaa gactggtgat    600

agtaaatctt aaaacagtcc agtggcaatc tgctgctcag ttaataatta ctaaaattct    660

tggatccctg aatagaaatt aaaaaaaaaa aatacaagag gcagtagagt caatacaagc    720

ttaatacaag cttagagtaa atacaagctt agagtcactt gatgactgtt ttactgttct    780

ccatattgtt tttattttta attaggccct accatagtat ttcacactaa aaacaaagga    840

attatattgg ctaatatagt ctttgactca tttcggtatc tcagtaaaag taaactgtct    900

tttcattgtt tcaccagttg gtggtgaaaa tagcagtatg catgcattat cactggtgtc    960

acaaactgta agctttgtaa gttagcactt tactcctata gctgatgtaa tcaaacttta   1020

aaataaacat ttcactaaac cttttaaaaa taatacattt gttttggatt gtatagcacg   1080

accatgtggt accaatttgg atgaattctt gatagattta aatagtgtat gtaattttgt   1140

aatgcttaga ctcttgaaga gctactttct gttttaatgt taagattctt gtgtcttagt   1200

tttttttaac atggatgtaa ttccatgtaa acaggtatgg aagtaggaaa tgtttaggct   1260

ggacttggtg gattattaat tgactttctt gggttcttgg gagtcaacat tactaaagca   1320

gtgtgaatcc ctgtttgctt cagggcgaga tgtgtgacag aggtggcatc aagctcttac   1380

agtcccaacc ctccaacgga aatgggcgaa gatctcagga atggcatcgg tcacaggaaa   1440

tcgatagtgg ctggctgcta gcatggccac ttggggctta ggcagaaata gagccatggt   1500

actgaccaaa gggaccatag cacatggaat aaaactcaaa acaggacttc atgttttatg   1560

gaaattatat ttaaccactt caacattgta aatctggata acttttaata tctaaactat   1620

ataagaaagt aaaatttaac atgttaatat ggaaaatttt tttatttttg tatcttgatg   1680

acttaaatgt aagcaacaaa gtggttaaac acatacccat ctaaattttt ttatagcctt   1740

ccatgttaaa ctataagtaa ataattagtt ttaaaattgt tttgtatttt cttattcctg   1800

ttccctttac cctttgacaa cttgaaatgt taccacttcg tcctcatgat gttcttctat   1860

caaccctgct taggatgaga acaagttgag cagtgccaac ggccatgaag aacgtagc     1918


<210>  9976
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9976

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9977
<211>  2145
<212>  DNA
<213>  Homo sapiens

<400>  9977
atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg gagcttgtcg     60

acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct cccgcctggg    120

cctaggggct taacagtagc aacagaagcg gcggcggcgg cagcagcagc agcagcagca    180

gcaatctctt cccgaacacg agcaccacag gcgcccgaag gccggaacag gcgtttagag    240

aaaatggcag acgatattga tattgaagca atgcttgagg ctccttacaa gaaggtgaga    300

aaaaacatgt cggtgaggtt tatatatttc ttaatttagc attattcacg aaactactgc    360

tgaaatgtaa actaacctcc ccggagccct cttgatttat cttatcagag atgcattacg    420

tgtaacttac aaaagtaaat atatgctatt gatgtaataa tattgtgcag tagtttcact    480

tcagcgtgat gaataaatgc ccatctatct ctctttgtag acttgcctaa cgatatctca    540

cctctactcc catgaattca cctttgattc cagtgtgaac tgtcaatcat aaggtagtaa    600

ttgagtgact tatcgctgta ccgtggtccc ctaggtaaaa tgactcaact aagaattacc    660

acctccagtt tggtatagca aaaaggtgaa tgtagtggtt tgggaaaaag caggggtcca    720

agaataacaa agcatgacca gtctgtggca agttaaatct tctaacagtc ttataagaag    780

aaatgggtga gattttaaaa tttatgtatc tatgtaagac tggtgatagt aaatcttaaa    840

acagtccagt ggcaatctgc tgctcagtta ataattacta aaattcttgg atccctgaat    900

agaaattaaa aaaaaaaaat acaagaggca gtagagtcaa tacaagctta atacaagctt    960

agagtaaata caagcttaga gtcacttgat gactgtttta ctgttctcca tattgttttt   1020

atttttaatt aggccctacc atagtatttc acactaaaaa caaaggaatt atattggcta   1080

atatagtctt tgactcattt cggtatctca gtaaaagtaa actgtctttt cattgtttca   1140

ccagttggtg gtgaaaatag cagtatgcat gcattatcac tggtgtcaca aactgtaagc   1200

tttgtaagtt agcactttac tcctatagct gatgtaatca aactttaaaa taaacatttc   1260

actaaacctt ttaaaaataa tacatttgtt ttggattgta tagcacgacc atgtggtacc   1320

aatttggatg aattcttgat agatttaaat agtgtatgta attttgtaat gcttagactc   1380

ttgaagagct actttctgtt ttaatgttaa gattcttgtg tcttagtttt ttttaacatg   1440

gatgtaattc catgtaaaca ggtatggaag taggaaatgt ttaggctgga cttggtggat   1500

tattaattga ctttcttggg ttcttgggag tcaacattac taaagcagtg tgaatccctg   1560

tttgcttcag ggcgagatgt gtgacagagg tggcatcaag ctcttacagt cccaaccctc   1620

caacggaaat gggcgaagat ctcaggaatg gcatcggtca caggaaatcg atagtggctg   1680

gctgctagca tggccacttg gggcttaggc agaaatagag ccatggtact gaccaaaggg   1740

accatagcac atggaataaa actcaaaaca ggacttcatg ttttatggaa attatattta   1800

accacttcaa cattgtaaat ctggataact tttaatatct aaactatata agaaagtaaa   1860

atttaacatg ttaatatgga aaattttttt atttttgtat cttgatgact taaatgtaag   1920

caacaaagtg gttaaacaca tacccatcta aattttttta tagccttcca tgttaaacta   1980

taagtaaata attagtttta aaattgtttt gtattttctt attcctgttc cctttaccct   2040

ttgacaactt gaaatgttac cacttcgtcc tcatgatgtt cttctatcaa ccctgcttag   2100

gatgagaaca agttgagcag tgccaacggc catgaagaac gtagc                   2145


<210>  9978
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  9978

Met Cys Ala Gly Glu Cys Glu Tyr Arg Glu Ala Ala Ala Ala Ile Ser 
1               5                   10                  15


Gly Ser Leu Ser Thr Leu Ser Gln Gly Trp Ile Leu Ser Cys Arg Ser 
            20                  25                  30


Arg Arg Pro Ala Leu Pro Pro Gly Pro Arg Gly Leu Thr Val Ala Thr 
        35                  40                  45


Glu Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ala Ile Ser Ser 
    50                  55                  60


Arg Thr Arg Ala Pro Gln Ala Pro Glu Gly Arg Asn Arg Arg Leu Glu 
65                  70                  75                  80


Lys Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr 
                85                  90                  95


Lys Lys Val Arg Lys Asn Met Ser Val Arg Phe Ile Tyr Phe Leu Ile 
            100                 105                 110


<210>  9979
<211>  1886
<212>  DNA
<213>  Homo sapiens

<400>  9979
gtgtgtgtat gtgtgctggt gaatattctc tcgggcctag ccgtccttgg aacccgatat     60

tcgggctggg cggttccgcg gcctgggcct aggggcttaa cagtagcaac agaagcggcg    120

gcggcggcag cagcagcagc agcagcagca atctcttccc gaacacgagc accacaggcg    180

cccgaaggcc ggaacaggcg tttagagaaa atggcagacg atattgatat tgaagcaatg    240

cttgaggctc cttacaagaa gacttgccta acgatatctc acctctactc ccatgaattc    300

acctttgatt ccagtgtgaa ctgtcaatca taaggtagta attgagtgac ttatcgctgt    360

accgtggtcc cctaggtaaa atgactcaac taagaattac cacctccagt ttggtatagc    420

aaaaaggtga atgtagtggt ttgggaaaaa gcaggggtcc aagaataaca aagcatgacc    480

agtctgtggc aagttaaatc ttctaacagt cttataagaa gaaatgggtg agattttaaa    540

atttatgtat ctatgtaaga ctggtgatag taaatcttaa aacagtccag tggcaatctg    600

ctgctcagtt aataattact aaaattcttg gatccctgaa tagaaattaa aaaaaaaaaa    660

tacaagaggc agtagagtca atacaagctt aatacaagct tagagtaaat acaagcttag    720

agtcacttga tgactgtttt actgttctcc atattgtttt tatttttaat taggccctac    780

catagtattt cacactaaaa acaaaggaat tatattggct aatatagtct ttgactcatt    840

tcggtatctc agtaaaagta aactgtcttt tcattgtttc accagttggt ggtgaaaata    900

gcagtatgca tgcattatca ctggtgtcac aaactgtaag ctttgtaagt tagcacttta    960

ctcctatagc tgatgtaatc aaactttaaa ataaacattt cactaaacct tttaaaaata   1020

atacatttgt tttggattgt atagcacgac catgtggtac caatttggat gaattcttga   1080

tagatttaaa tagtgtatgt aattttgtaa tgcttagact cttgaagagc tactttctgt   1140

tttaatgtta agattcttgt gtcttagttt tttttaacat ggatgtaatt ccatgtaaac   1200

aggtatggaa gtaggaaatg tttaggctgg acttggtgga ttattaattg actttcttgg   1260

gttcttggga gtcaacatta ctaaagcagt gtgaatccct gtttgcttca gggcgagatg   1320

tgtgacagag gtggcatcaa gctcttacag tcccaaccct ccaacggaaa tgggcgaaga   1380

tctcaggaat ggcatcggtc acaggaaatc gatagtggct ggctgctagc atggccactt   1440

ggggcttagg cagaaataga gccatggtac tgaccaaagg gaccatagca catggaataa   1500

aactcaaaac aggacttcat gttttatgga aattatattt aaccacttca acattgtaaa   1560

tctggataac ttttaatatc taaactatat aagaaagtaa aatttaacat gttaatatgg   1620

aaaatttttt tatttttgta tcttgatgac ttaaatgtaa gcaacaaagt ggttaaacac   1680

atacccatct aaattttttt atagccttcc atgttaaact ataagtaaat aattagtttt   1740

aaaattgttt tgtattttct tattcctgtt ccctttaccc tttgacaact tgaaatgtta   1800

ccacttcgtc ctcatgatgt tcttctatca accctgctta ggatgagaac aagttgagca   1860

gtgccaacgg ccatgaagaa cgtagc                                        1886


<210>  9980
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9980

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9981
<211>  439
<212>  DNA
<213>  Homo sapiens

<400>  9981
gtgtgtgtgt atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg     60

gagcttgtcg acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct    120

cccgcgtggg cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct    180

tggaacccga tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc    240

aacagaagcg gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg    300

agcaccacag gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga    360

tattgaagca atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa    420

cggccatgaa gaacgtagc                                                 439


<210>  9982
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  9982

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Asp Glu Asn Lys Leu Ser Ser Ala Asn Gly His Glu Glu Arg 
            20                  25                  30


<210>  9983
<211>  2114
<212>  DNA
<213>  Homo sapiens

<400>  9983
gtgtgtgtgt atgtgtgctg gtgaatattc tctcgggcct agccgtcctt ggaacccgat     60

attcgggctg ggcggttccg cggcctgggc ctaggggctt aacagtagca acagaagcgg    120

cggcggcggc agcagcagca gcagcagcag caatctcttc ccgaacacga gcaccacagg    180

cgcccgaagg ccggaacagg cgtttagaga aaatggcaga cgatattgat attgaagcaa    240

tgcttgaggc tccttacaag aaggtgagaa aaaacatgtc ggtgaggttt atatatttct    300

taatttagca ttattcacga aactactgct gaaatgtaaa ctaacctccc cggagccctc    360

ttgatttatc ttatcagaga tgcattacgt gtaacttaca aaagtaaata tatgctattg    420

atgtaataat attgtgcagt agtttcactt cagcgtgatg aataaatgcc catctatctc    480

tctttgtaga cttgcctaac gatatctcac ctctactccc atgaattcac ctttgattcc    540

agtgtgaact gtcaatcata aggtagtaat tgagtgactt atcgctgtac cgtggtcccc    600

taggtaaaat gactcaacta agaattacca cctccagttt ggtatagcaa aaaggtgaat    660

gtagtggttt gggaaaaagc aggggtccaa gaataacaaa gcatgaccag tctgtggcaa    720

gttaaatctt ctaacagtct tataagaaga aatgggtgag attttaaaat ttatgtatct    780

atgtaagact ggtgatagta aatcttaaaa cagtccagtg gcaatctgct gctcagttaa    840

taattactaa aattcttgga tccctgaata gaaattaaaa aaaaaaaata caagaggcag    900

tagagtcaat acaagcttaa tacaagctta gagtaaatac aagcttagag tcacttgatg    960

actgttttac tgttctccat attgttttta tttttaatta ggccctacca tagtatttca   1020

cactaaaaac aaaggaatta tattggctaa tatagtcttt gactcatttc ggtatctcag   1080

taaaagtaaa ctgtcttttc attgtttcac cagttggtgg tgaaaatagc agtatgcatg   1140

cattatcact ggtgtcacaa actgtaagct ttgtaagtta gcactttact cctatagctg   1200

atgtaatcaa actttaaaat aaacatttca ctaaaccttt taaaaataat acatttgttt   1260

tggattgtat agcacgacca tgtggtacca atttggatga attcttgata gatttaaata   1320

gtgtatgtaa ttttgtaatg cttagactct tgaagagcta ctttctgttt taatgttaag   1380

attcttgtgt cttagttttt tttaacatgg atgtaattcc atgtaaacag gtatggaagt   1440

aggaaatgtt taggctggac ttggtggatt attaattgac tttcttgggt tcttgggagt   1500

caacattact aaagcagtgt gaatccctgt ttgcttcagg gcgagatgtg tgacagaggt   1560

ggcatcaagc tcttacagtc ccaaccctcc aacggaaatg ggcgaagatc tcaggaatgg   1620

catcggtcac aggaaatcga tagtggctgg ctgctagcat ggccacttgg ggcttaggca   1680

gaaatagagc catggtactg accaaaggga ccatagcaca tggaataaaa ctcaaaacag   1740

gacttcatgt tttatggaaa ttatatttaa ccacttcaac attgtaaatc tggataactt   1800

ttaatatcta aactatataa gaaagtaaaa tttaacatgt taatatggaa aattttttta   1860

tttttgtatc ttgatgactt aaatgtaagc aacaaagtgg ttaaacacat acccatctaa   1920

atttttttat agccttccat gttaaactat aagtaaataa ttagttttaa aattgttttg   1980

tattttctta ttcctgttcc ctttaccctt tgacaacttg aaatgttacc acttcgtcct   2040

catgatgttc ttctatcaac cctgcttagg atgagaacaa gttgagcagt gccaacggcc   2100

atgaagaacg tagc                                                     2114


<210>  9984
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9984

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9985
<211>  2051
<212>  DNA
<213>  Homo sapiens

<400>  9985
gtgctgaggg ctctgtgagg ccccgtgtgt ttgtgtgtgt gtatgtgtgc tggtgaatgt     60

gagtacaggg aagcagcggc cgccatttca gggagcttgt cgacgctgtc gcaggggtgg    120

atcctgagct gccgaagccg ccgtcctgct ctcccgcgtg ggcttctcta attccattgt    180

tttttttaga ttctctcggg cctagccgtc cttggaaccc gatattcggg ctgggcggtt    240

ccgcggcctg ggcctagggg cttaacagta gcaacagaag cggcggcggc ggcagcagca    300

gcagcagcag cagcaatctc ttcccgaaca cgagcaccac aggcgcccga aggccggaac    360

aggcgtttag agaaaatggc agacgatatt gatattgaag caatgcttga ggctccttac    420

aagaagactt gcctaacgat atctcacctc tactcccatg aattcacctt tgattccagt    480

gtgaactgtc aatcataagg tagtaattga gtgacttatc gctgtaccgt ggtcccctag    540

gtaaaatgac tcaactaaga attaccacct ccagtttggt atagcaaaaa ggtgaatgta    600

gtggtttggg aaaaagcagg ggtccaagaa taacaaagca tgaccagtct gtggcaagtt    660

aaatcttcta acagtcttat aagaagaaat gggtgagatt ttaaaattta tgtatctatg    720

taagactggt gatagtaaat cttaaaacag tccagtggca atctgctgct cagttaataa    780

ttactaaaat tcttggatcc ctgaatagaa attaaaaaaa aaaaatacaa gaggcagtag    840

agtcaataca agcttaatac aagcttagag taaatacaag cttagagtca cttgatgact    900

gttttactgt tctccatatt gtttttattt ttaattaggc cctaccatag tatttcacac    960

taaaaacaaa ggaattatat tggctaatat agtctttgac tcatttcggt atctcagtaa   1020

aagtaaactg tcttttcatt gtttcaccag ttggtggtga aaatagcagt atgcatgcat   1080

tatcactggt gtcacaaact gtaagctttg taagttagca ctttactcct atagctgatg   1140

taatcaaact ttaaaataaa catttcacta aaccttttaa aaataataca tttgttttgg   1200

attgtatagc acgaccatgt ggtaccaatt tggatgaatt cttgatagat ttaaatagtg   1260

tatgtaattt tgtaatgctt agactcttga agagctactt tctgttttaa tgttaagatt   1320

cttgtgtctt agtttttttt aacatggatg taattccatg taaacaggta tggaagtagg   1380

aaatgtttag gctggacttg gtggattatt aattgacttt cttgggttct tgggagtcaa   1440

cattactaaa gcagtgtgaa tccctgtttg cttcagggcg agatgtgtga cagaggtggc   1500

atcaagctct tacagtccca accctccaac ggaaatgggc gaagatctca ggaatggcat   1560

cggtcacagg aaatcgatag tggctggctg ctagcatggc cacttggggc ttaggcagaa   1620

atagagccat ggtactgacc aaagggacca tagcacatgg aataaaactc aaaacaggac   1680

ttcatgtttt atggaaatta tatttaacca cttcaacatt gtaaatctgg ataactttta   1740

atatctaaac tatataagaa agtaaaattt aacatgttaa tatggaaaat ttttttattt   1800

ttgtatcttg atgacttaaa tgtaagcaac aaagtggtta aacacatacc catctaaatt   1860

tttttatagc cttccatgtt aaactataag taaataatta gttttaaaat tgttttgtat   1920

tttcttattc ctgttccctt taccctttga caacttgaaa tgttaccact tcgtcctcat   1980

gatgttcttc tatcaaccct gcttaggatg agaacaagtt gagcagtgcc aacggccatg   2040

aagaacgtag c                                                        2051


<210>  9986
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9986

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9987
<211>  2313
<212>  DNA
<213>  Homo sapiens

<400>  9987
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga aggtgagaaa aaacatgtcg    480

gtgaggttta tatatttctt aatttagcat tattcacgaa actactgctg aaatgtaaac    540

taacctcccc ggagccctct tgatttatct tatcagagat gcattacgtg taacttacaa    600

aagtaaatat atgctattga tgtaataata ttgtgcagta gtttcacttc agcgtgatga    660

ataaatgccc atctatctct ctttgtagac ttgcctaacg atatctcacc tctactccca    720

tgaattcacc tttgattcca gtgtgaactg tcaatcataa ggtagtaatt gagtgactta    780

tcgctgtacc gtggtcccct aggtaaaatg actcaactaa gaattaccac ctccagtttg    840

gtatagcaaa aaggtgaatg tagtggtttg ggaaaaagca ggggtccaag aataacaaag    900

catgaccagt ctgtggcaag ttaaatcttc taacagtctt ataagaagaa atgggtgaga    960

ttttaaaatt tatgtatcta tgtaagactg gtgatagtaa atcttaaaac agtccagtgg   1020

caatctgctg ctcagttaat aattactaaa attcttggat ccctgaatag aaattaaaaa   1080

aaaaaaatac aagaggcagt agagtcaata caagcttaat acaagcttag agtaaataca   1140

agcttagagt cacttgatga ctgttttact gttctccata ttgtttttat ttttaattag   1200

gccctaccat agtatttcac actaaaaaca aaggaattat attggctaat atagtctttg   1260

actcatttcg gtatctcagt aaaagtaaac tgtcttttca ttgtttcacc agttggtggt   1320

gaaaatagca gtatgcatgc attatcactg gtgtcacaaa ctgtaagctt tgtaagttag   1380

cactttactc ctatagctga tgtaatcaaa ctttaaaata aacatttcac taaacctttt   1440

aaaaataata catttgtttt ggattgtata gcacgaccat gtggtaccaa tttggatgaa   1500

ttcttgatag atttaaatag tgtatgtaat tttgtaatgc ttagactctt gaagagctac   1560

tttctgtttt aatgttaaga ttcttgtgtc ttagtttttt ttaacatgga tgtaattcca   1620

tgtaaacagg tatggaagta ggaaatgttt aggctggact tggtggatta ttaattgact   1680

ttcttgggtt cttgggagtc aacattacta aagcagtgtg aatccctgtt tgcttcaggg   1740

cgagatgtgt gacagaggtg gcatcaagct cttacagtcc caaccctcca acggaaatgg   1800

gcgaagatct caggaatggc atcggtcaca ggaaatcgat agtggctggc tgctagcatg   1860

gccacttggg gcttaggcag aaatagagcc atggtactga ccaaagggac catagcacat   1920

ggaataaaac tcaaaacagg acttcatgtt ttatggaaat tatatttaac cacttcaaca   1980

ttgtaaatct ggataacttt taatatctaa actatataag aaagtaaaat ttaacatgtt   2040

aatatggaaa atttttttat ttttgtatct tgatgactta aatgtaagca acaaagtggt   2100

taaacacata cccatctaaa tttttttata gccttccatg ttaaactata agtaaataat   2160

tagttttaaa attgttttgt attttcttat tcctgttccc tttacccttt gacaacttga   2220

aatgttacca cttcgtcctc atgatgttct tctatcaacc ctgcttagga tgagaacaag   2280

ttgagcagtg ccaacggcca tgaagaacgt agc                                2313


<210>  9988
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9988

Met Cys Asp Arg Gly Gly Ile Lys Leu Leu Gln Ser Gln Pro Ser Asn 
1               5                   10                  15


Gly Asn Gly Arg Arg Ser Gln Glu Trp His Arg Ser Gln Glu Ile Asp 
            20                  25                  30


Ser Gly Trp Leu Leu Ala Trp Pro Leu Gly Ala 
        35                  40


<210>  9989
<211>  1110
<212>  DNA
<213>  Homo sapiens

<400>  9989
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataagggcga    540

gatgtgtgac agaggtggca tcaagctctt acagtcccaa ccctccaacg gaaatgggcg    600

aagatctcag gaatggcatc ggtcacagga aatcgatagt ggctggctgc tagcatggcc    660

acttggggct taggcagaaa tagagccatg gtactgacca aagggaccat agcacatgga    720

ataaaactca aaacaggact tcatgtttta tggaaattat atttaaccac ttcaacattg    780

taaatctgga taacttttaa tatctaaact atataagaaa gtaaaattta acatgttaat    840

atggaaaatt tttttatttt tgtatcttga tgacttaaat gtaagcaaca aagtggttaa    900

acacataccc atctaaattt ttttatagcc ttccatgtta aactataagt aaataattag    960

ttttaaaatt gttttgtatt ttcttattcc tgttcccttt accctttgac aacttgaaat   1020

gttaccactt cgtcctcatg atgttcttct atcaaccctg cttaggatga gaacaagttg   1080

agcagtgcca acggccatga agaacgtagc                                    1110


<210>  9990
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9990

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9991
<211>  580
<212>  DNA
<213>  Homo sapiens

<400>  9991
aaatttggag cttggggcag cttctcgcga gagcccgtgc tgagggctct gtgaggcccc     60

gtgtgtttgt gtgtgtgtat gtgtgctggt gaatgtgagt acagggaagc agcggccgcc    120

atttcaggga gcttgtcgac gctgtcgcag gggtggatcc tgagctgccg aagccgccgt    180

cctgctctcc cgcgtgggct tctctaattc cattgttttt tttagattct ctcgggccta    240

gccgtccttg gaacccgata ttcgggctgg gcggttccgc ggcctgggcc taggggctta    300

acagtagcaa cagaagcggc ggcggcggca gcagcagcag cagcagcagc aatctcttcc    360

cgaacacgag caccacaggc gcccgaaggc cggaacaggc gtttagagaa aatggcagac    420

gatattgata ttgaagcaat gcttgaggct ccttacaaga agacttgcct aacgatatct    480

cacctctact cccatgaatt cacctttgat tccagtgtga actgtcaatc ataaggatga    540

gaacaagttg agcagtgcca acggccatga agaacgtagc                          580


<210>  9992
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  9992

Met Ala Asp Asp Ile Asp Ile Glu Ala Met Leu Glu Ala Pro Tyr Lys 
1               5                   10                  15


Lys Thr Cys Leu Thr Ile Ser His Leu Tyr Ser His Glu Phe Thr Phe 
            20                  25                  30


Asp Ser Ser Val Asn Cys Gln Ser 
        35                  40


<210>  9993
<211>  668
<212>  DNA
<213>  Homo sapiens

<400>  9993
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgagatc ttattcaggg cttctcagcc    120

tgaaccccca accagattaa tttctccaca gctggaattc caagtgcttg gggataatga    180

tacctctgac ctttcttcct tttgggaagt acttgagtgt gcagctgcat gaggcctcag    240

caggagagag attttaggtc caagaagcta taccagtagg acaaggcagg aaaatactac    300

actttcagga tcaagcccct ctgactctca tttggaaact ggatgtttgc taagcacctg    360

cttcttaagg atgccgaggg atttaatgat actcccagaa acctggagag attaatgggg    420

cctatggaga agtgctctga actcagtgtt gggacttgaa taaaattaac cattgtcatg    480

ttttcagaac aactaagctg ttttatattt catgtgcatg aaagccctag aactaagttg    540

tgttatttcc agaaatgaaa tagatcccac agttagatga tgtggccatt aggaagtacc    600

aaatttataa aaatcactgg aggtctgtct gagcagtacc taataaaata tagtatactg    660

aaagtgaa                                                             668


<210>  9994
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  9994

Met Phe Ala Lys His Leu Leu Leu Lys Asp Ala Glu Gly Phe Asn Asp 
1               5                   10                  15


Thr Pro Arg Asn Leu Glu Arg Leu Met Gly Pro Met Glu Lys Cys Ser 
            20                  25                  30


Glu Leu Ser Val Gly Thr 
        35


<210>  9995
<211>  579
<212>  DNA
<213>  Homo sapiens

<400>  9995
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tggtactttt acatttttct gttaattaaa    240

gcccttcagt aaaggatttt tgccagcact gatagagtgg tagcttaggc tttttttgtg    300

gtgtttttct acttcctgac tcttggaaga tgtgaggaaa tgtcagtctt ttctctttga    360

tgcagggatc ccagtgtcag ggtgactgtc ctgtaacccc ctgtatatat ttgtttcccc    420

cttttgcctg ttcatctgaa agagttctgg gaaaaagaag caggaatggc tacagggaag    480

ggaagagtta atagtggcag ctctcttgct cctggctgcc tgtctgaaaa aagaggaaag    540

atcagggatg gaatagtgaa gaaaaagggg ttcgattgg                           579


<210>  9996
<211>  43
<212>  PRT
<213>  Homo sapiens

<400>  9996

Met Gln Gly Ser Gln Cys Gln Gly Asp Cys Pro Val Thr Pro Cys Ile 
1               5                   10                  15


Tyr Leu Phe Pro Pro Phe Ala Cys Ser Ser Glu Arg Val Leu Gly Lys 
            20                  25                  30


Arg Ser Arg Asn Gly Tyr Arg Glu Gly Lys Ser 
        35                  40


<210>  9997
<211>  431
<212>  DNA
<213>  Homo sapiens

<400>  9997
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tgaatacagt tgagttttgc caaatttgac    240

agttcacgca agccccacca caatcaagat atgggccggg aatggtgact catgcctata    300

atcccagcac cttgggagga caacgtggga ggattgcttg agcccaggag ttcaagacaa    360

gcctaagcaa cataatggga cttcgtctct caaaaaaaaa aaaaaaaaac cataataaaa    420

gtaataataa t                                                         431


<210>  9998
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  9998

Tyr Ala Gly Arg Val Pro Gly Val Thr Trp Cys Arg Ala Arg Arg Val 
1               5                   10                  15


Leu Leu Ser Val Gly Pro Gly Ala Ala Gln Pro Glu Trp Gly Arg Glu 
            20                  25                  30


Glu Asn Lys Gly Ser Pro Val Asp Asp 
        35                  40


<210>  9999
<211>  529
<212>  DNA
<213>  Homo sapiens

<400>  9999
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tgagtgtttc agtggtaatg ccgtgtgttt    240

catattgcat cacatcgggg gacacataaa gctaggtcgt cccactgttc cgtgtatcac    300

ttggataaga atacagttga gttttgccaa atttgacagt tcacgcaagc cccaccacaa    360

tcaagatatg ggccgggaat ggtgactcat gcctataatc ccagcacctt gggaggacaa    420

cgtgggagga ttgcttgagc ccaggagttc aagacaagcc taagcaacat aatgggactt    480

cgtctctcaa aaaaaaaaaa aaaaaaccat aataaaagta ataataata                529


<210>  10000
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  10000

Tyr Ala Gly Arg Val Pro Gly Val Thr Trp Cys Arg Ala Arg Arg Val 
1               5                   10                  15


Leu Leu Ser Val Gly Pro Gly Ala Ala Gln Pro Glu Trp Gly Arg Glu 
            20                  25                  30


Glu Asn Lys Gly Ser Pro Val Asp Asp 
        35                  40


<210>  10001
<211>  986
<212>  DNA
<213>  Homo sapiens

<400>  10001
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tggtatccag ctcacataga agacattgac    240

tacgaggaag gaaaagtact catccatttc aagcgttgga accatcgtta tgatgagtgg    300

ttctgctggg acagtcctta tttacgccct ttagagaaaa tacagctgag gaaagagggc    360

ttgcatgaag aggatggatc ttctgaattt caaataaatg agcaggtcct tgcttgctgg    420

tctgattgtc gtttttaccc ggccaaagtc actgctgtta acaaggatgg tacttacact    480

gtgaaatttt atgatggagt agttcagact gtcaaacata ttcatgtcaa agctttttcc    540

aaagatcaga atattgtggg taatgctagg cctaaagaaa cagatcacaa aagtctttca    600

tcatctcctg ataaacgaga gaagtttaaa gaacagagaa aagcaacagt gaatgtgaag    660

aaagacaaag aagataaacc cttaaagaca gaaaagcgac ccaagcagcc tgataaagaa    720

ggaaagttaa tctgttctga aaaggggaaa gtgtcagaga aaagtcttcc caagaacgag    780

aaggaagaca aggaaaacat ttccgaaaat gacagagagt attctggaga tgcccaagtg    840

gataagaaac ctgaaaatga cattgtgaag agtccacaag aaaacttgag ggaacccaaa    900

agaaaacgag gcagaccccc ttccatagct cctactgctg tggattcaaa ctctcaaact    960

ttgcaaccaa taacattgga actgag                                         986


<210>  10002
<211>  284
<212>  PRT
<213>  Homo sapiens

<400>  10002

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu 
        275                 280


<210>  10003
<211>  1751
<212>  DNA
<213>  Homo sapiens

<400>  10003
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tggtatccag ctcacataga agacattgac    240

tacgaggaag gaaaagtact catccatttc aagcgttgga accatcgtta tgatgagtgg    300

ttctgctggg acagtcctta tttacgccct ttagagaaaa tacagctgag gaaagagggc    360

ttgcatgaag aggatggatc ttctgaattt caaataaatg agcaggtcct tgcttgctgg    420

tctgattgtc gtttttaccc ggccaaagtc actgctgtta acaaggatgg tacttacact    480

gtgaaatttt atgatggagt agttcagact gtcaaacata ttcatgtcaa agctttttcc    540

aaagatcaga atattgtggg taatgctagg cctaaagaaa cagatcacaa aagtctttca    600

tcatctcctg ataaacgaga gaagtttaaa gaacagagaa aagcaacagt gaatgtgaag    660

aaagacaaag aagataaacc cttaaagaca gaaaagcgac ccaagcagcc tgataaagaa    720

ggaaagttaa tctgttctga aaaggggaaa gtgtcagaga aaagtcttcc caagaacgag    780

aaggaagaca aggaaaacat ttccgaaaat gacagagagt attctggaga tgcccaagtg    840

gataagaaac ctgaaaatga cattgtgaag agtccacaag aaaacttgag ggaacccaaa    900

agaaaacgag gcagaccccc ttccatagct cctactgctg tggattcaaa ctctcaaact    960

ttgcaaccaa taacattgga actgagaaga aggaaaatat caaaaggatg tgaagtccca   1020

ttaaaacgtc ctcggcttga caaaaattca tcccaggaaa agtcaaaaaa ctactcggaa   1080

aacactgaca aagacttatc gaggagacgt tcctccaggc tgtccactaa tgggacccat   1140

gagatcctag atcctgactt ggttgtatca gatttggttg atacggatcc tttgcaagac   1200

acgttgtcta gtaccaagga atctgaagaa ggtcagttga agtctgcttt ggaagctggc   1260

caggtctcat ctgcactgac ttgccactcc tttggggatg gatccggggc tgcaggcttg   1320

gagttgaact gcccatcaat gggagaaaac acgatgaaaa cagaaccgac ttctcccctt   1380

gtggaattac aagagatttc gactgtggaa gtaacaaata cttttaagaa aacagatgat   1440

tttgggtcat ctaatgcacc agctgtcgac ctagaccata agtttagatg caaagttgtg   1500

gactgtttaa aatttttccg caaagccaaa ctgttgcact atcacatgaa gtatttccat   1560

ggaatggaga agtcactgga gccagaagag agcccgggaa agaggcatgt ccaaaccagg   1620

ggcccttcag cttcagacaa gcccagccag gagaccctga ccaggaagcg ggtctctgcc   1680

agttccccaa ctacaaaaga caaggaaaag aataaagaga agaaattcaa ggagtttgtg   1740

agagtgaagc c                                                        1751


<210>  10004
<211>  539
<212>  PRT
<213>  Homo sapiens

<400>  10004

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val 
    530                 535


<210>  10005
<211>  6203
<212>  DNA
<213>  Homo sapiens

<400>  10005
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggct ggaatgcagt gacatcatct    120

cagagctgac tgcaacctct gcctcctgga ttcaagcaat tctcctgcct cagcctcccg    180

agtagctagg attacaggcg gatgccacca tgcccggcta atttttgtat ttttggaaga    240

gatgggtttt caccatattc gccaagctag tcttgaactc ctgacctcaa gtgatccact    300

ctcctcggcc tcccaaagtg ctaggattac aggccactgt gcctggccaa gaggtcactt    360

ttcatgtcca ggctgcatgg agaataaagg cagccccgtt gatgactgaa aatgacaaag    420

catccaccta acagacgagg aatcagcttt gaagtgggag cccagttgga agcccgggac    480

cgtttaaaaa actggtatcc agctcacata gaagacattg actacgagga aggaaaagta    540

ctcatccatt tcaagcgttg gaaccatcgt tatgatgagt ggttctgctg ggacagtcct    600

tatttacgcc ctttagagaa aatacagctg aggaaagagg gcttgcatga agaggatgga    660

tcttctgaat ttcaaataaa tgagcaggtc cttgcttgct ggtctgattg tcgtttttac    720

ccggccaaag tcactgctgt taacaaggat ggtacttaca ctgtgaaatt ttatgatgga    780

gtagttcaga ctgtcaaaca tattcatgtc aaagcttttt ccaaagatca gaatattgtg    840

ggtaatgcta ggcctaaaga aacagatcac aaaagtcttt catcatctcc tgataaacga    900

gagaagttta aagaacagag aaaagcaaca gtgaatgtga agaaagacaa agaagataaa    960

cccttaaaga cagaaaagcg acccaagcag cctgataaag aaggaaagtt aatctgttct   1020

gaaaagggga aagtgtcaga gaaaagtctt cccaagaacg agaaggaaga caaggaaaac   1080

atttccgaaa atgacagaga gtattctgga gatgcccaag tggataagaa acctgaaaat   1140

gacattgtga agagtccaca agaaaacttg agggaaccca aaagaaaacg aggcagaccc   1200

ccttccatag ctcctactgc tgtggattca aactctcaaa ctttgcaacc aataacattg   1260

gaactgagaa gaaggaaaat atcaaaagga tgtgaagtcc cattaaaacg tcctcggctt   1320

gacaaaaatt catcccagga aaagtcaaaa aactactcgg aaaacactga caaagactta   1380

tcgaggagac gttcctccag gctgtccact aatgggaccc atgagatcct agatcctgac   1440

ttggttgtat cagatttggt tgatacggat cctttgcaag acacgttgtc tagtaccaag   1500

gaatctgaag aaggtcagtt gaagtctgct ttggaagctg gccaggtctc atctgcactg   1560

acttgccact cctttgggga tggatccggg gctgcaggct tggagttgaa ctgcccatca   1620

atgggagaaa acacgatgaa aacagaaccg acttctcccc ttgtggaatt acaagagatt   1680

tcgactgtgg aagtaacaaa tacttttaag aaaacagatg attttgggtc atctaatgca   1740

ccagctgtcg acctagacca taagtttaga tgcaaagttg tggactgttt aaaatttttc   1800

cgcaaagcca aactgttgca ctatcacatg aagtatttcc atggaatgga gaagtcactg   1860

gagccagaag agagcccggg aaagaggcat gtccaaacca ggggcccttc agcttcagac   1920

aagcccagcc aggagaccct gaccaggaag cgggtctctg ccagttcccc aactacaaaa   1980

gacaaggaaa agaataaaga gaagaaattc aaggagtttg tgagagtgaa gccaaagaag   2040

aaaaagaaaa agaaaaagaa aaccaaacct gaatgcccct gcagtgagga gatcagtgac   2100

acctcccagg aaccttctcc acccaaggca tttgctgtta ccaggtgtgg gtcctcacac   2160

aagccagggg tccatatgag cccgcagctt catggcccag aatctggaca ccacaaaggg   2220

aaagtgaaag cattggagga ggataatttg agtgagtcct cttctgagag ctttctctgg   2280

agtgatgatg agtatggcca agatgtggat gtgaccacca acccagatga ggaacttgat   2340

ggggatgacc gctatgactt cgaggtggtc cgctgcatct gtgaggtcca ggaggaaaat   2400

gacttcatga ttcagtgtga agagtgccag tgctggcagc atggggtctg catgggatta   2460

ctggaagaaa atgtgcccga gaaatacacc tgttatgttt gccaagaccc tccaggtcag   2520

aggcctggct tcaagtactg gtatgacaag gagtggctga gcaggggaca tatgcatggc   2580

ctggcatttc tagaagagaa ctactcccat cagaatgcca agaagatcgt ggccacccac   2640

cagcttcttg gtgatgtgca gagagtgatt gaggttctgc atggcctgca gctcaagatg   2700

agcatcttgc aaagccggga gcatcctgat ctgccgctgt ggtgccagcc ttggaaacag   2760

cactcagggg aggggagatc tcatttcaga aacatccctg tcactgacac caggagcaag   2820

gaggaagctc caagctatag aactttgaac ggggcagtgg agaagcccag gcccctggcc   2880

ctgcccctgc cgcgttctgt ggaggaatcc tatatcacca gtgagcattg ctaccagaag   2940

ccccgcgcct attaccctgc cgtggagcag aagctggtgg tggagacgag gggctctgcc   3000

ctcgacgatg cggtcaaccc cctccatgag aacggcgatg attccctttc cccgcgcctg   3060

ggctggcctc tagaccaaga caggagcaag ggggacagtg accccaaacc cggctcccca   3120

aaggtgaagg aatatgtctc caaaaaggcc ctaccagaag aagcccctgc tcggaagctg   3180

ctggacagag gtggagaggg gctgctgagc tcccagcacc agtggcagtt taacctgctg   3240

acccatgtgg aatctcttca ggatgaagtt acgcacagga tggactccat tgagaaggag   3300

ttggatgtgt tggagagctg gctggactac actggggaac tggagccccc tgagccgctg   3360

gccaggcttc cgcagctcaa gcattgtatc aagcagctgc tgatggacct gggcaaggtg   3420

cagcagatcg ccctctgctg ctcaacatga aactgggcac ccaaaactca tgggggcaca   3480

atcctggggc acctgcagga ggagcttcgc atatttaaat aaataaacct agcatgctga   3540

atgcacgtga caccgactga cttcagggat ctgggccagg agtgtggtgg acattggaca   3600

aagaggccat tttggctgcg ggaggacact ctgatctcga agcctgccat aaaggtagca   3660

aatagactct tgggattccc ctcttctgtg cacatcgttg aatgaagaga gtctttttgc   3720

acaaacttca cttgaaattg tgccactgat gataaacgga atgagagcca aaaaagttta   3780

gttggagaca gttgtaaatt caatttggag tttatttaat tgacttttct atcacgttgg   3840

ggcacatgcc aactccctgg tttcttcctg gcatggtgtt tgggcagcag gcatcatttt   3900

ccttttctag cttcatagga atattgtgag ctcaccatgc tgtggaggtt gggaaagagc   3960

agagtcttgg ctgccctgct ttctccttag gactcttcac ttttctcacc acatctcttg   4020

catgacttca tggtactggg gacaagtttg tatgccttca ccccagagct ggctgggtta   4080

tggcttttgt agcagagccc atacagccta tggaagaact agaatctcac tcacagtaat   4140

aagaatctag gaggaattcc aaaccgaagc aggcagggtc tggaacccaa aggacagcat   4200

tttctaccca cttcttaata ttgacagctt ccccgttcta tttaatgtcc aaaaatgttt   4260

cccaaaattt caaactcttt cactgtaaag atttgttaca aagaatgtgg tttggggaat   4320

taccttattt tatattgttg taaacaaact tcaaattcta catgtgcgac ttttctcctt   4380

cctgaagggt gtttagtagt cagcgttttc agaattgttt tgttactata ctttaacatt   4440

ttacatttcc tgtttgtatt attttgtgag agcaaggtga tcatgctgct taaggtccag   4500

gtacaaccta tttgtacctt ttgagacaat atttgtgtta cttttgcagg ttacggttcc   4560

acatgtaatt gctatatttt gttttgtttt tccttactag gcaaagttaa aatgttccat   4620

gctttgagga gtgacccatt tcactacttt gttttcttat cactaaaggc aaaaatcaaa   4680

gcacagttgt ccattaacac ttataagtta attatgggtt tatgagtctg taatgttata   4740

tgctgcaaac atttactatg taaacgtgaa gtagccaata atatctcaat agtagtaaca   4800

gtatctttag cgacctttgg aatagttaag cacaggtcat tgtggacatg aattcaggcc   4860

tctgtactaa aatctatttc agggaatgtt ctgtctagtg atttgctcac catttgatat   4920

ataatgaatt ataggacaag tataagctga tctgctatag ctgtccatca gagagaatac   4980

acgtggctat aacatctata acaaaacgac gattcctcta caagaggctg tttctcactg   5040

ctaacgttgg tgtttctggc gtgggaagaa atgcacaggc gtgcatggca tgcacgttca   5100

gacagctgca ttgtaagagt tctgtcatgc agtctgaaaa gggaagaaac aggatggctt   5160

tctgtagcca cacctgtgag gcgtgatgat tgttgtatta ttagattact gatttttctt   5220

ttctgaaaat acatttgagt tttaatcaca tctgtggaag ctgtaacttt taaggtagtc   5280

aatttcatgt cttgttcaac gatgtaagca gaaactgaat tgccctaatt ttgccaactg   5340

gccattattg ggattattgt ttaaattttt ggtaaaggaa gtaatctcct ttcattcatt   5400

gtgacttttg ttcttaggga agcagagaag actccccaag ttcttataac ctcattgtgc   5460

ttccctaatt taaagccatg ttgaggggct ccattcccaa ttcctgggtc aaggtgaatt   5520

aaccctatgt tggagcactg gaaaccgtta tttgcaaaca ttgctgttac catttagaaa   5580

tatgtgcact atcagctggg tgcagtggct cacgtctgta atcccagcac tttgggaggc   5640

cgaggcaggt ggatcacctg aggtcaggag ttcgagacca gcctggccaa cagggtgaaa   5700

ccccgtctct actaaaagta caaaaattag ctgggcgtgg tggcggacgc ctgtaatctc   5760

agctacttgg gaggctgaag caggagaggt gctggaacct gggaggcgga ggttgaagtg   5820

agccgagatt gcgctattgc actccagctc gggcgacaac tgcaagactc catctcaaaa   5880

aaataaaaat aaaagaaaag aaagaaatat gtgcactacc taagttttgt ctttagaaaa   5940

actatccacc tataaaaaat taccttgaca aaaatagttc cggtttgact aatcattttg   6000

tttctttaag tggtaagtgt atgcaaggtg gatccttgat gagccaacat tgcactgtgg   6060

atacatatct atgtttacgc gctattagaa cagaaggcgc tgtatataga aatgttgctt   6120

tgaagcaata tttgcaaaac acgcagactt ctgtatctgt atttggaaaa aataaaacag   6180

gttcttgttg ctatgtttca gtt                                           6203


<210>  10006
<211>  1012
<212>  PRT
<213>  Homo sapiens

<400>  10006

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val Lys Pro Lys Lys Lys 
    530                 535                 540


Lys Lys Lys Lys Lys Lys Thr Lys Pro Glu Cys Pro Cys Ser Glu Glu 
545                 550                 555                 560


Ile Ser Asp Thr Ser Gln Glu Pro Ser Pro Pro Lys Ala Phe Ala Val 
                565                 570                 575


Thr Arg Cys Gly Ser Ser His Lys Pro Gly Val His Met Ser Pro Gln 
            580                 585                 590


Leu His Gly Pro Glu Ser Gly His His Lys Gly Lys Val Lys Ala Leu 
        595                 600                 605


Glu Glu Asp Asn Leu Ser Glu Ser Ser Ser Glu Ser Phe Leu Trp Ser 
    610                 615                 620


Asp Asp Glu Tyr Gly Gln Asp Val Asp Val Thr Thr Asn Pro Asp Glu 
625                 630                 635                 640


Glu Leu Asp Gly Asp Asp Arg Tyr Asp Phe Glu Val Val Arg Cys Ile 
                645                 650                 655


Cys Glu Val Gln Glu Glu Asn Asp Phe Met Ile Gln Cys Glu Glu Cys 
            660                 665                 670


Gln Cys Trp Gln His Gly Val Cys Met Gly Leu Leu Glu Glu Asn Val 
        675                 680                 685


Pro Glu Lys Tyr Thr Cys Tyr Val Cys Gln Asp Pro Pro Gly Gln Arg 
    690                 695                 700


Pro Gly Phe Lys Tyr Trp Tyr Asp Lys Glu Trp Leu Ser Arg Gly His 
705                 710                 715                 720


Met His Gly Leu Ala Phe Leu Glu Glu Asn Tyr Ser His Gln Asn Ala 
                725                 730                 735


Lys Lys Ile Val Ala Thr His Gln Leu Leu Gly Asp Val Gln Arg Val 
            740                 745                 750


Ile Glu Val Leu His Gly Leu Gln Leu Lys Met Ser Ile Leu Gln Ser 
        755                 760                 765


Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln Pro Trp Lys Gln His 
    770                 775                 780


Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile Pro Val Thr Asp Thr 
785                 790                 795                 800


Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr Leu Asn Gly Ala Val 
                805                 810                 815


Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro Arg Ser Val Glu Glu 
            820                 825                 830


Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys Pro Arg Ala Tyr Tyr 
        835                 840                 845


Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr Arg Gly Ser Ala Leu 
    850                 855                 860


Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly Asp Asp Ser Leu Ser 
865                 870                 875                 880


Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg Ser Lys Gly Asp Ser 
                885                 890                 895


Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu Tyr Val Ser Lys Lys 
            900                 905                 910


Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu Leu Asp Arg Gly Gly 
        915                 920                 925


Glu Gly Leu Leu Ser Ser Gln His Gln Trp Gln Phe Asn Leu Leu Thr 
    930                 935                 940


His Val Glu Ser Leu Gln Asp Glu Val Thr His Arg Met Asp Ser Ile 
945                 950                 955                 960


Glu Lys Glu Leu Asp Val Leu Glu Ser Trp Leu Asp Tyr Thr Gly Glu 
                965                 970                 975


Leu Glu Pro Pro Glu Pro Leu Ala Arg Leu Pro Gln Leu Lys His Cys 
            980                 985                 990


Ile Lys Gln Leu Leu Met Asp Leu Gly Lys Val Gln Gln Ile Ala Leu 
        995                 1000                1005


Cys Cys Ser Thr 
    1010


<210>  10007
<211>  5921
<212>  DNA
<213>  Homo sapiens

<400>  10007
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggag aataaaggca gccccgttga    120

tgactgaaaa tgacaaagca tccacctaac agacgaggaa tcagctttga agtgggagcc    180

cagttggaag cccgggaccg tttaaaaaac tggtatccag ctcacataga agacattgac    240

tacgaggaag gaaaagtact catccatttc aagcgttgga accatcgtta tgatgagtgg    300

ttctgctggg acagtcctta tttacgccct ttagagaaaa tacagctgag gaaagagggc    360

ttgcatgaag aggatggatc ttctgaattt caaataaatg agcaggtcct tgcttgctgg    420

tctgattgtc gtttttaccc ggccaaagtc actgctgtta acaaggatgg tacttacact    480

gtgaaatttt atgatggagt agttcagact gtcaaacata ttcatgtcaa agctttttcc    540

aaagatcaga atattgtggg taatgctagg cctaaagaaa cagatcacaa aagtctttca    600

tcatctcctg ataaacgaga gaagtttaaa gaacagagaa aagcaacagt gaatgtgaag    660

aaagacaaag aagataaacc cttaaagaca gaaaagcgac ccaagcagcc tgataaagaa    720

ggaaagttaa tctgttctga aaaggggaaa gtgtcagaga aaagtcttcc caagaacgag    780

aaggaagaca aggaaaacat ttccgaaaat gacagagagt attctggaga tgcccaagtg    840

gataagaaac ctgaaaatga cattgtgaag agtccacaag aaaacttgag ggaacccaaa    900

agaaaacgag gcagaccccc ttccatagct cctactgctg tggattcaaa ctctcaaact    960

ttgcaaccaa taacattgga actgagaaga aggaaaatat caaaaggatg tgaagtccca   1020

ttaaaacgtc ctcggcttga caaaaattca tcccaggaaa agtcaaaaaa ctactcggaa   1080

aacactgaca aagacttatc gaggagacgt tcctccaggc tgtccactaa tgggacccat   1140

gagatcctag atcctgactt ggttgtatca gatttggttg atacggatcc tttgcaagac   1200

acgttgtcta gtaccaagga atctgaagaa ggtcagttga agtctgcttt ggaagctggc   1260

caggtctcat ctgcactgac ttgccactcc tttggggatg gatccggggc tgcaggcttg   1320

gagttgaact gcccatcaat gggagaaaac acgatgaaaa cagaaccgac ttctcccctt   1380

gtggaattac aagagatttc gactgtggaa gtaacaaata cttttaagaa aacagatgat   1440

tttgggtcat ctaatgcacc agctgtcgac ctagaccata agtttagatg caaagttgtg   1500

gactgtttaa aatttttccg caaagccaaa ctgttgcact atcacatgaa gtatttccat   1560

ggaatggaga agtcactgga gccagaagag agcccgggaa agaggcatgt ccaaaccagg   1620

ggcccttcag cttcagacaa gcccagccag gagaccctga ccaggaagcg ggtctctgcc   1680

agttccccaa ctacaaaaga caaggaaaag aataaagaga agaaattcaa ggagtttgtg   1740

agagtgaagc caaagaagaa aaagaaaaag aaaaagaaaa ccaaacctga atgcccctgc   1800

agtgaggaga tcagtgacac ctcccaggaa ccttctccac ccaaggcatt tgctgttacc   1860

aggtgtgggt cctcacacaa gccaggggtc catatgagcc cgcagcttca tggcccagaa   1920

tctggacacc acaaagggaa agtgaaagca ttggaggagg ataatttgag tgagtcctct   1980

tctgagagct ttctctggag tgatgatgag tatggccaag atgtggatgt gaccaccaac   2040

ccagatgagg aacttgatgg ggatgaccgc tatgacttcg aggtggtccg ctgcatctgt   2100

gaggtccagg aggaaaatga cttcatgatt cagtgtgaag agtgccagtg ctggcagcat   2160

ggggtctgca tgggattact ggaagaaaat gtgcccgaga aatacacctg ttatgtttgc   2220

caagaccctc caggtcagag gcctggcttc aagtactggt atgacaagga gtggctgagc   2280

aggggacata tgcatggcct ggcatttcta gaagagaact actcccatca gaatgccaag   2340

aagatcgtgg ccacccacca gcttcttggt gatgtgcaga gagtgattga ggttctgcat   2400

ggcctgcagc tcaagatgag catcttgcaa agccgggagc atcctgatct gccgctgtgg   2460

tgccagcctt ggaaacagca ctcaggggag gggagatctc atttcagaaa catccctgtc   2520

actgacacca ggagcaagga ggaagctcca agctatagaa ctttgaacgg ggcagtggag   2580

aagcccaggc ccctggccct gcccctgccg cgttctgtgg aggaatccta tatcaccagt   2640

gagcattgct accagaagcc ccgcgcctat taccctgccg tggagcagaa gctggtggtg   2700

gagacgaggg gctctgccct cgacgatgcg gtcaaccccc tccatgagaa cggcgatgat   2760

tccctttccc cgcgcctggg ctggcctcta gaccaagaca ggagcaaggg ggacagtgac   2820

cccaaacccg gctccccaaa ggtgaaggaa tatgtctcca aaaaggccct accagaagaa   2880

gcccctgctc ggaagctgct ggacagaggt ggagaggggc tgctgagctc ccagcaccag   2940

tggcagttta acctgctgac ccatgtggaa tctcttcagg atgaagttac gcacaggatg   3000

gactccattg agaaggagtt ggatgtgttg gagagctggc tggactacac tggggaactg   3060

gagccccctg agccgctggc caggcttccg cagctcaagc attgtatcaa gcagctgctg   3120

atggacctgg gcaaggtgca gcagatcgcc ctctgctgct caacatgaaa ctgggcaccc   3180

aaaactcatg ggggcacaat cctggggcac ctgcaggagg agcttcgcat atttaaataa   3240

ataaacctag catgctgaat gcacgtgaca ccgactgact tcagggatct gggccaggag   3300

tgtggtggac attggacaaa gaggccattt tggctgcggg aggacactct gatctcgaag   3360

cctgccataa aggtagcaaa tagactcttg ggattcccct cttctgtgca catcgttgaa   3420

tgaagagagt ctttttgcac aaacttcact tgaaattgtg ccactgatga taaacggaat   3480

gagagccaaa aaagtttagt tggagacagt tgtaaattca atttggagtt tatttaattg   3540

acttttctat cacgttgggg cacatgccaa ctccctggtt tcttcctggc atggtgtttg   3600

ggcagcaggc atcattttcc ttttctagct tcataggaat attgtgagct caccatgctg   3660

tggaggttgg gaaagagcag agtcttggct gccctgcttt ctccttagga ctcttcactt   3720

ttctcaccac atctcttgca tgacttcatg gtactgggga caagtttgta tgccttcacc   3780

ccagagctgg ctgggttatg gcttttgtag cagagcccat acagcctatg gaagaactag   3840

aatctcactc acagtaataa gaatctagga ggaattccaa accgaagcag gcagggtctg   3900

gaacccaaag gacagcattt tctacccact tcttaatatt gacagcttcc ccgttctatt   3960

taatgtccaa aaatgtttcc caaaatttca aactctttca ctgtaaagat ttgttacaaa   4020

gaatgtggtt tggggaatta ccttatttta tattgttgta aacaaacttc aaattctaca   4080

tgtgcgactt ttctccttcc tgaagggtgt ttagtagtca gcgttttcag aattgttttg   4140

ttactatact ttaacatttt acatttcctg tttgtattat tttgtgagag caaggtgatc   4200

atgctgctta aggtccaggt acaacctatt tgtacctttt gagacaatat ttgtgttact   4260

tttgcaggtt acggttccac atgtaattgc tatattttgt tttgtttttc cttactaggc   4320

aaagttaaaa tgttccatgc tttgaggagt gacccatttc actactttgt tttcttatca   4380

ctaaaggcaa aaatcaaagc acagttgtcc attaacactt ataagttaat tatgggttta   4440

tgagtctgta atgttatatg ctgcaaacat ttactatgta aacgtgaagt agccaataat   4500

atctcaatag tagtaacagt atctttagcg acctttggaa tagttaagca caggtcattg   4560

tggacatgaa ttcaggcctc tgtactaaaa tctatttcag ggaatgttct gtctagtgat   4620

ttgctcacca tttgatatat aatgaattat aggacaagta taagctgatc tgctatagct   4680

gtccatcaga gagaatacac gtggctataa catctataac aaaacgacga ttcctctaca   4740

agaggctgtt tctcactgct aacgttggtg tttctggcgt gggaagaaat gcacaggcgt   4800

gcatggcatg cacgttcaga cagctgcatt gtaagagttc tgtcatgcag tctgaaaagg   4860

gaagaaacag gatggctttc tgtagccaca cctgtgaggc gtgatgattg ttgtattatt   4920

agattactga tttttctttt ctgaaaatac atttgagttt taatcacatc tgtggaagct   4980

gtaactttta aggtagtcaa tttcatgtct tgttcaacga tgtaagcaga aactgaattg   5040

ccctaatttt gccaactggc cattattggg attattgttt aaatttttgg taaaggaagt   5100

aatctccttt cattcattgt gacttttgtt cttagggaag cagagaagac tccccaagtt   5160

cttataacct cattgtgctt ccctaattta aagccatgtt gaggggctcc attcccaatt   5220

cctgggtcaa ggtgaattaa ccctatgttg gagcactgga aaccgttatt tgcaaacatt   5280

gctgttacca tttagaaata tgtgcactat cagctgggtg cagtggctca cgtctgtaat   5340

cccagcactt tgggaggccg aggcaggtgg atcacctgag gtcaggagtt cgagaccagc   5400

ctggccaaca gggtgaaacc ccgtctctac taaaagtaca aaaattagct gggcgtggtg   5460

gcggacgcct gtaatctcag ctacttggga ggctgaagca ggagaggtgc tggaacctgg   5520

gaggcggagg ttgaagtgag ccgagattgc gctattgcac tccagctcgg gcgacaactg   5580

caagactcca tctcaaaaaa ataaaaataa aagaaaagaa agaaatatgt gcactaccta   5640

agttttgtct ttagaaaaac tatccaccta taaaaaatta ccttgacaaa aatagttccg   5700

gtttgactaa tcattttgtt tctttaagtg gtaagtgtat gcaaggtgga tccttgatga   5760

gccaacattg cactgtggat acatatctat gtttacgcgc tattagaaca gaaggcgctg   5820

tatatagaaa tgttgctttg aagcaatatt tgcaaaacac gcagacttct gtatctgtat   5880

ttggaaaaaa taaaacaggt tcttgttgct atgtttcagt t                       5921


<210>  10008
<211>  1012
<212>  PRT
<213>  Homo sapiens

<400>  10008

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val Lys Pro Lys Lys Lys 
    530                 535                 540


Lys Lys Lys Lys Lys Lys Thr Lys Pro Glu Cys Pro Cys Ser Glu Glu 
545                 550                 555                 560


Ile Ser Asp Thr Ser Gln Glu Pro Ser Pro Pro Lys Ala Phe Ala Val 
                565                 570                 575


Thr Arg Cys Gly Ser Ser His Lys Pro Gly Val His Met Ser Pro Gln 
            580                 585                 590


Leu His Gly Pro Glu Ser Gly His His Lys Gly Lys Val Lys Ala Leu 
        595                 600                 605


Glu Glu Asp Asn Leu Ser Glu Ser Ser Ser Glu Ser Phe Leu Trp Ser 
    610                 615                 620


Asp Asp Glu Tyr Gly Gln Asp Val Asp Val Thr Thr Asn Pro Asp Glu 
625                 630                 635                 640


Glu Leu Asp Gly Asp Asp Arg Tyr Asp Phe Glu Val Val Arg Cys Ile 
                645                 650                 655


Cys Glu Val Gln Glu Glu Asn Asp Phe Met Ile Gln Cys Glu Glu Cys 
            660                 665                 670


Gln Cys Trp Gln His Gly Val Cys Met Gly Leu Leu Glu Glu Asn Val 
        675                 680                 685


Pro Glu Lys Tyr Thr Cys Tyr Val Cys Gln Asp Pro Pro Gly Gln Arg 
    690                 695                 700


Pro Gly Phe Lys Tyr Trp Tyr Asp Lys Glu Trp Leu Ser Arg Gly His 
705                 710                 715                 720


Met His Gly Leu Ala Phe Leu Glu Glu Asn Tyr Ser His Gln Asn Ala 
                725                 730                 735


Lys Lys Ile Val Ala Thr His Gln Leu Leu Gly Asp Val Gln Arg Val 
            740                 745                 750


Ile Glu Val Leu His Gly Leu Gln Leu Lys Met Ser Ile Leu Gln Ser 
        755                 760                 765


Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln Pro Trp Lys Gln His 
    770                 775                 780


Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile Pro Val Thr Asp Thr 
785                 790                 795                 800


Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr Leu Asn Gly Ala Val 
                805                 810                 815


Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro Arg Ser Val Glu Glu 
            820                 825                 830


Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys Pro Arg Ala Tyr Tyr 
        835                 840                 845


Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr Arg Gly Ser Ala Leu 
    850                 855                 860


Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly Asp Asp Ser Leu Ser 
865                 870                 875                 880


Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg Ser Lys Gly Asp Ser 
                885                 890                 895


Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu Tyr Val Ser Lys Lys 
            900                 905                 910


Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu Leu Asp Arg Gly Gly 
        915                 920                 925


Glu Gly Leu Leu Ser Ser Gln His Gln Trp Gln Phe Asn Leu Leu Thr 
    930                 935                 940


His Val Glu Ser Leu Gln Asp Glu Val Thr His Arg Met Asp Ser Ile 
945                 950                 955                 960


Glu Lys Glu Leu Asp Val Leu Glu Ser Trp Leu Asp Tyr Thr Gly Glu 
                965                 970                 975


Leu Glu Pro Pro Glu Pro Leu Ala Arg Leu Pro Gln Leu Lys His Cys 
            980                 985                 990


Ile Lys Gln Leu Leu Met Asp Leu Gly Lys Val Gln Gln Ile Ala Leu 
        995                 1000                1005


Cys Cys Ser Thr 
    1010


<210>  10009
<211>  6001
<212>  DNA
<213>  Homo sapiens

<400>  10009
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgagcac gagtacacga gacaggattg    120

agaaaggaga gattcaaatt gtgacttcag attcaaaggc aattaaagga attaaacgag    180

aataaaggca gccccgttga tgactgaaaa tgacaaagca tccacctaac agacgaggaa    240

tcagctttga agtgggagcc cagttggaag cccgggaccg tttaaaaaac tggtatccag    300

ctcacataga agacattgac tacgaggaag gaaaagtact catccatttc aagcgttgga    360

accatcgtta tgatgagtgg ttctgctggg acagtcctta tttacgccct ttagagaaaa    420

tacagctgag gaaagagggc ttgcatgaag aggatggatc ttctgaattt caaataaatg    480

agcaggtcct tgcttgctgg tctgattgtc gtttttaccc ggccaaagtc actgctgtta    540

acaaggatgg tacttacact gtgaaatttt atgatggagt agttcagact gtcaaacata    600

ttcatgtcaa agctttttcc aaagatcaga atattgtggg taatgctagg cctaaagaaa    660

cagatcacaa aagtctttca tcatctcctg ataaacgaga gaagtttaaa gaacagagaa    720

aagcaacagt gaatgtgaag aaagacaaag aagataaacc cttaaagaca gaaaagcgac    780

ccaagcagcc tgataaagaa ggaaagttaa tctgttctga aaaggggaaa gtgtcagaga    840

aaagtcttcc caagaacgag aaggaagaca aggaaaacat ttccgaaaat gacagagagt    900

attctggaga tgcccaagtg gataagaaac ctgaaaatga cattgtgaag agtccacaag    960

aaaacttgag ggaacccaaa agaaaacgag gcagaccccc ttccatagct cctactgctg   1020

tggattcaaa ctctcaaact ttgcaaccaa taacattgga actgagaaga aggaaaatat   1080

caaaaggatg tgaagtccca ttaaaacgtc ctcggcttga caaaaattca tcccaggaaa   1140

agtcaaaaaa ctactcggaa aacactgaca aagacttatc gaggagacgt tcctccaggc   1200

tgtccactaa tgggacccat gagatcctag atcctgactt ggttgtatca gatttggttg   1260

atacggatcc tttgcaagac acgttgtcta gtaccaagga atctgaagaa ggtcagttga   1320

agtctgcttt ggaagctggc caggtctcat ctgcactgac ttgccactcc tttggggatg   1380

gatccggggc tgcaggcttg gagttgaact gcccatcaat gggagaaaac acgatgaaaa   1440

cagaaccgac ttctcccctt gtggaattac aagagatttc gactgtggaa gtaacaaata   1500

cttttaagaa aacagatgat tttgggtcat ctaatgcacc agctgtcgac ctagaccata   1560

agtttagatg caaagttgtg gactgtttaa aatttttccg caaagccaaa ctgttgcact   1620

atcacatgaa gtatttccat ggaatggaga agtcactgga gccagaagag agcccgggaa   1680

agaggcatgt ccaaaccagg ggcccttcag cttcagacaa gcccagccag gagaccctga   1740

ccaggaagcg ggtctctgcc agttccccaa ctacaaaaga caaggaaaag aataaagaga   1800

agaaattcaa ggagtttgtg agagtgaagc caaagaagaa aaagaaaaag aaaaagaaaa   1860

ccaaacctga atgcccctgc agtgaggaga tcagtgacac ctcccaggaa ccttctccac   1920

ccaaggcatt tgctgttacc aggtgtgggt cctcacacaa gccaggggtc catatgagcc   1980

cgcagcttca tggcccagaa tctggacacc acaaagggaa agtgaaagca ttggaggagg   2040

ataatttgag tgagtcctct tctgagagct ttctctggag tgatgatgag tatggccaag   2100

atgtggatgt gaccaccaac ccagatgagg aacttgatgg ggatgaccgc tatgacttcg   2160

aggtggtccg ctgcatctgt gaggtccagg aggaaaatga cttcatgatt cagtgtgaag   2220

agtgccagtg ctggcagcat ggggtctgca tgggattact ggaagaaaat gtgcccgaga   2280

aatacacctg ttatgtttgc caagaccctc caggtcagag gcctggcttc aagtactggt   2340

atgacaagga gtggctgagc aggggacata tgcatggcct ggcatttcta gaagagaact   2400

actcccatca gaatgccaag aagatcgtgg ccacccacca gcttcttggt gatgtgcaga   2460

gagtgattga ggttctgcat ggcctgcagc tcaagatgag catcttgcaa agccgggagc   2520

atcctgatct gccgctgtgg tgccagcctt ggaaacagca ctcaggggag gggagatctc   2580

atttcagaaa catccctgtc actgacacca ggagcaagga ggaagctcca agctatagaa   2640

ctttgaacgg ggcagtggag aagcccaggc ccctggccct gcccctgccg cgttctgtgg   2700

aggaatccta tatcaccagt gagcattgct accagaagcc ccgcgcctat taccctgccg   2760

tggagcagaa gctggtggtg gagacgaggg gctctgccct cgacgatgcg gtcaaccccc   2820

tccatgagaa cggcgatgat tccctttccc cgcgcctggg ctggcctcta gaccaagaca   2880

ggagcaaggg ggacagtgac cccaaacccg gctccccaaa ggtgaaggaa tatgtctcca   2940

aaaaggccct accagaagaa gcccctgctc ggaagctgct ggacagaggt ggagaggggc   3000

tgctgagctc ccagcaccag tggcagttta acctgctgac ccatgtggaa tctcttcagg   3060

atgaagttac gcacaggatg gactccattg agaaggagtt ggatgtgttg gagagctggc   3120

tggactacac tggggaactg gagccccctg agccgctggc caggcttccg cagctcaagc   3180

attgtatcaa gcagctgctg atggacctgg gcaaggtgca gcagatcgcc ctctgctgct   3240

caacatgaaa ctgggcaccc aaaactcatg ggggcacaat cctggggcac ctgcaggagg   3300

agcttcgcat atttaaataa ataaacctag catgctgaat gcacgtgaca ccgactgact   3360

tcagggatct gggccaggag tgtggtggac attggacaaa gaggccattt tggctgcggg   3420

aggacactct gatctcgaag cctgccataa aggtagcaaa tagactcttg ggattcccct   3480

cttctgtgca catcgttgaa tgaagagagt ctttttgcac aaacttcact tgaaattgtg   3540

ccactgatga taaacggaat gagagccaaa aaagtttagt tggagacagt tgtaaattca   3600

atttggagtt tatttaattg acttttctat cacgttgggg cacatgccaa ctccctggtt   3660

tcttcctggc atggtgtttg ggcagcaggc atcattttcc ttttctagct tcataggaat   3720

attgtgagct caccatgctg tggaggttgg gaaagagcag agtcttggct gccctgcttt   3780

ctccttagga ctcttcactt ttctcaccac atctcttgca tgacttcatg gtactgggga   3840

caagtttgta tgccttcacc ccagagctgg ctgggttatg gcttttgtag cagagcccat   3900

acagcctatg gaagaactag aatctcactc acagtaataa gaatctagga ggaattccaa   3960

accgaagcag gcagggtctg gaacccaaag gacagcattt tctacccact tcttaatatt   4020

gacagcttcc ccgttctatt taatgtccaa aaatgtttcc caaaatttca aactctttca   4080

ctgtaaagat ttgttacaaa gaatgtggtt tggggaatta ccttatttta tattgttgta   4140

aacaaacttc aaattctaca tgtgcgactt ttctccttcc tgaagggtgt ttagtagtca   4200

gcgttttcag aattgttttg ttactatact ttaacatttt acatttcctg tttgtattat   4260

tttgtgagag caaggtgatc atgctgctta aggtccaggt acaacctatt tgtacctttt   4320

gagacaatat ttgtgttact tttgcaggtt acggttccac atgtaattgc tatattttgt   4380

tttgtttttc cttactaggc aaagttaaaa tgttccatgc tttgaggagt gacccatttc   4440

actactttgt tttcttatca ctaaaggcaa aaatcaaagc acagttgtcc attaacactt   4500

ataagttaat tatgggttta tgagtctgta atgttatatg ctgcaaacat ttactatgta   4560

aacgtgaagt agccaataat atctcaatag tagtaacagt atctttagcg acctttggaa   4620

tagttaagca caggtcattg tggacatgaa ttcaggcctc tgtactaaaa tctatttcag   4680

ggaatgttct gtctagtgat ttgctcacca tttgatatat aatgaattat aggacaagta   4740

taagctgatc tgctatagct gtccatcaga gagaatacac gtggctataa catctataac   4800

aaaacgacga ttcctctaca agaggctgtt tctcactgct aacgttggtg tttctggcgt   4860

gggaagaaat gcacaggcgt gcatggcatg cacgttcaga cagctgcatt gtaagagttc   4920

tgtcatgcag tctgaaaagg gaagaaacag gatggctttc tgtagccaca cctgtgaggc   4980

gtgatgattg ttgtattatt agattactga tttttctttt ctgaaaatac atttgagttt   5040

taatcacatc tgtggaagct gtaactttta aggtagtcaa tttcatgtct tgttcaacga   5100

tgtaagcaga aactgaattg ccctaatttt gccaactggc cattattggg attattgttt   5160

aaatttttgg taaaggaagt aatctccttt cattcattgt gacttttgtt cttagggaag   5220

cagagaagac tccccaagtt cttataacct cattgtgctt ccctaattta aagccatgtt   5280

gaggggctcc attcccaatt cctgggtcaa ggtgaattaa ccctatgttg gagcactgga   5340

aaccgttatt tgcaaacatt gctgttacca tttagaaata tgtgcactat cagctgggtg   5400

cagtggctca cgtctgtaat cccagcactt tgggaggccg aggcaggtgg atcacctgag   5460

gtcaggagtt cgagaccagc ctggccaaca gggtgaaacc ccgtctctac taaaagtaca   5520

aaaattagct gggcgtggtg gcggacgcct gtaatctcag ctacttggga ggctgaagca   5580

ggagaggtgc tggaacctgg gaggcggagg ttgaagtgag ccgagattgc gctattgcac   5640

tccagctcgg gcgacaactg caagactcca tctcaaaaaa ataaaaataa aagaaaagaa   5700

agaaatatgt gcactaccta agttttgtct ttagaaaaac tatccaccta taaaaaatta   5760

ccttgacaaa aatagttccg gtttgactaa tcattttgtt tctttaagtg gtaagtgtat   5820

gcaaggtgga tccttgatga gccaacattg cactgtggat acatatctat gtttacgcgc   5880

tattagaaca gaaggcgctg tatatagaaa tgttgctttg aagcaatatt tgcaaaacac   5940

gcagacttct gtatctgtat ttggaaaaaa taaaacaggt tcttgttgct atgtttcagt   6000

t                                                                   6001


<210>  10010
<211>  1012
<212>  PRT
<213>  Homo sapiens

<400>  10010

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val Lys Pro Lys Lys Lys 
    530                 535                 540


Lys Lys Lys Lys Lys Lys Thr Lys Pro Glu Cys Pro Cys Ser Glu Glu 
545                 550                 555                 560


Ile Ser Asp Thr Ser Gln Glu Pro Ser Pro Pro Lys Ala Phe Ala Val 
                565                 570                 575


Thr Arg Cys Gly Ser Ser His Lys Pro Gly Val His Met Ser Pro Gln 
            580                 585                 590


Leu His Gly Pro Glu Ser Gly His His Lys Gly Lys Val Lys Ala Leu 
        595                 600                 605


Glu Glu Asp Asn Leu Ser Glu Ser Ser Ser Glu Ser Phe Leu Trp Ser 
    610                 615                 620


Asp Asp Glu Tyr Gly Gln Asp Val Asp Val Thr Thr Asn Pro Asp Glu 
625                 630                 635                 640


Glu Leu Asp Gly Asp Asp Arg Tyr Asp Phe Glu Val Val Arg Cys Ile 
                645                 650                 655


Cys Glu Val Gln Glu Glu Asn Asp Phe Met Ile Gln Cys Glu Glu Cys 
            660                 665                 670


Gln Cys Trp Gln His Gly Val Cys Met Gly Leu Leu Glu Glu Asn Val 
        675                 680                 685


Pro Glu Lys Tyr Thr Cys Tyr Val Cys Gln Asp Pro Pro Gly Gln Arg 
    690                 695                 700


Pro Gly Phe Lys Tyr Trp Tyr Asp Lys Glu Trp Leu Ser Arg Gly His 
705                 710                 715                 720


Met His Gly Leu Ala Phe Leu Glu Glu Asn Tyr Ser His Gln Asn Ala 
                725                 730                 735


Lys Lys Ile Val Ala Thr His Gln Leu Leu Gly Asp Val Gln Arg Val 
            740                 745                 750


Ile Glu Val Leu His Gly Leu Gln Leu Lys Met Ser Ile Leu Gln Ser 
        755                 760                 765


Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln Pro Trp Lys Gln His 
    770                 775                 780


Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile Pro Val Thr Asp Thr 
785                 790                 795                 800


Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr Leu Asn Gly Ala Val 
                805                 810                 815


Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro Arg Ser Val Glu Glu 
            820                 825                 830


Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys Pro Arg Ala Tyr Tyr 
        835                 840                 845


Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr Arg Gly Ser Ala Leu 
    850                 855                 860


Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly Asp Asp Ser Leu Ser 
865                 870                 875                 880


Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg Ser Lys Gly Asp Ser 
                885                 890                 895


Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu Tyr Val Ser Lys Lys 
            900                 905                 910


Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu Leu Asp Arg Gly Gly 
        915                 920                 925


Glu Gly Leu Leu Ser Ser Gln His Gln Trp Gln Phe Asn Leu Leu Thr 
    930                 935                 940


His Val Glu Ser Leu Gln Asp Glu Val Thr His Arg Met Asp Ser Ile 
945                 950                 955                 960


Glu Lys Glu Leu Asp Val Leu Glu Ser Trp Leu Asp Tyr Thr Gly Glu 
                965                 970                 975


Leu Glu Pro Pro Glu Pro Leu Ala Arg Leu Pro Gln Leu Lys His Cys 
            980                 985                 990


Ile Lys Gln Leu Leu Met Asp Leu Gly Lys Val Gln Gln Ile Ala Leu 
        995                 1000                1005


Cys Cys Ser Thr 
    1010


<210>  10011
<211>  6059
<212>  DNA
<213>  Homo sapiens

<400>  10011
atacgctggg cgcgtcccgg gggtcacgtg gtgcagagca cgcagagtcc ttctgtcggt     60

tggtcctgga gcggcgcagc cggagtgggg ccgtgaggcg gagtctcact ctgtcgccca    120

gaagtgcagt ggtgcaacct cggcacactg caacctctgt ctcctgggtt caagcaattc    180

tcctgcctca gcctcctgag tagctgggat tacaggtgcc cgccaccatg cctgggagaa    240

taaaggcagc cccgttgatg actgaaaatg acaaagcatc cacctaacag acgaggaatc    300

agctttgaag tgggagccca gttggaagcc cgggaccgtt taaaaaactg gtatccagct    360

cacatagaag acattgacta cgaggaagga aaagtactca tccatttcaa gcgttggaac    420

catcgttatg atgagtggtt ctgctgggac agtccttatt tacgcccttt agagaaaata    480

cagctgagga aagagggctt gcatgaagag gatggatctt ctgaatttca aataaatgag    540

caggtccttg cttgctggtc tgattgtcgt ttttacccgg ccaaagtcac tgctgttaac    600

aaggatggta cttacactgt gaaattttat gatggagtag ttcagactgt caaacatatt    660

catgtcaaag ctttttccaa agatcagaat attgtgggta atgctaggcc taaagaaaca    720

gatcacaaaa gtctttcatc atctcctgat aaacgagaga agtttaaaga acagagaaaa    780

gcaacagtga atgtgaagaa agacaaagaa gataaaccct taaagacaga aaagcgaccc    840

aagcagcctg ataaagaagg aaagttaatc tgttctgaaa aggggaaagt gtcagagaaa    900

agtcttccca agaacgagaa ggaagacaag gaaaacattt ccgaaaatga cagagagtat    960

tctggagatg cccaagtgga taagaaacct gaaaatgaca ttgtgaagag tccacaagaa   1020

aacttgaggg aacccaaaag aaaacgaggc agaccccctt ccatagctcc tactgctgtg   1080

gattcaaact ctcaaacttt gcaaccaata acattggaac tgagaagaag gaaaatatca   1140

aaaggatgtg aagtcccatt aaaacgtcct cggcttgaca aaaattcatc ccaggaaaag   1200

tcaaaaaact actcggaaaa cactgacaaa gacttatcga ggagacgttc ctccaggctg   1260

tccactaatg ggacccatga gatcctagat cctgacttgg ttgtatcaga tttggttgat   1320

acggatcctt tgcaagacac gttgtctagt accaaggaat ctgaagaagg tcagttgaag   1380

tctgctttgg aagctggcca ggtctcatct gcactgactt gccactcctt tggggatgga   1440

tccggggctg caggcttgga gttgaactgc ccatcaatgg gagaaaacac gatgaaaaca   1500

gaaccgactt ctccccttgt ggaattacaa gagatttcga ctgtggaagt aacaaatact   1560

tttaagaaaa cagatgattt tgggtcatct aatgcaccag ctgtcgacct agaccataag   1620

tttagatgca aagttgtgga ctgtttaaaa tttttccgca aagccaaact gttgcactat   1680

cacatgaagt atttccatgg aatggagaag tcactggagc cagaagagag cccgggaaag   1740

aggcatgtcc aaaccagggg cccttcagct tcagacaagc ccagccagga gaccctgacc   1800

aggaagcggg tctctgccag ttccccaact acaaaagaca aggaaaagaa taaagagaag   1860

aaattcaagg agtttgtgag agtgaagcca aagaagaaaa agaaaaagaa aaagaaaacc   1920

aaacctgaat gcccctgcag tgaggagatc agtgacacct cccaggaacc ttctccaccc   1980

aaggcatttg ctgttaccag gtgtgggtcc tcacacaagc caggggtcca tatgagcccg   2040

cagcttcatg gcccagaatc tggacaccac aaagggaaag tgaaagcatt ggaggaggat   2100

aatttgagtg agtcctcttc tgagagcttt ctctggagtg atgatgagta tggccaagat   2160

gtggatgtga ccaccaaccc agatgaggaa cttgatgggg atgaccgcta tgacttcgag   2220

gtggtccgct gcatctgtga ggtccaggag gaaaatgact tcatgattca gtgtgaagag   2280

tgccagtgct ggcagcatgg ggtctgcatg ggattactgg aagaaaatgt gcccgagaaa   2340

tacacctgtt atgtttgcca agaccctcca ggtcagaggc ctggcttcaa gtactggtat   2400

gacaaggagt ggctgagcag gggacatatg catggcctgg catttctaga agagaactac   2460

tcccatcaga atgccaagaa gatcgtggcc acccaccagc ttcttggtga tgtgcagaga   2520

gtgattgagg ttctgcatgg cctgcagctc aagatgagca tcttgcaaag ccgggagcat   2580

cctgatctgc cgctgtggtg ccagccttgg aaacagcact caggggaggg gagatctcat   2640

ttcagaaaca tccctgtcac tgacaccagg agcaaggagg aagctccaag ctatagaact   2700

ttgaacgggg cagtggagaa gcccaggccc ctggccctgc ccctgccgcg ttctgtggag   2760

gaatcctata tcaccagtga gcattgctac cagaagcccc gcgcctatta ccctgccgtg   2820

gagcagaagc tggtggtgga gacgaggggc tctgccctcg acgatgcggt caaccccctc   2880

catgagaacg gcgatgattc cctttccccg cgcctgggct ggcctctaga ccaagacagg   2940

agcaaggggg acagtgaccc caaacccggc tccccaaagg tgaaggaata tgtctccaaa   3000

aaggccctac cagaagaagc ccctgctcgg aagctgctgg acagaggtgg agaggggctg   3060

ctgagctccc agcaccagtg gcagtttaac ctgctgaccc atgtggaatc tcttcaggat   3120

gaagttacgc acaggatgga ctccattgag aaggagttgg atgtgttgga gagctggctg   3180

gactacactg gggaactgga gccccctgag ccgctggcca ggcttccgca gctcaagcat   3240

tgtatcaagc agctgctgat ggacctgggc aaggtgcagc agatcgccct ctgctgctca   3300

acatgaaact gggcacccaa aactcatggg ggcacaatcc tggggcacct gcaggaggag   3360

cttcgcatat ttaaataaat aaacctagca tgctgaatgc acgtgacacc gactgacttc   3420

agggatctgg gccaggagtg tggtggacat tggacaaaga ggccattttg gctgcgggag   3480

gacactctga tctcgaagcc tgccataaag gtagcaaata gactcttggg attcccctct   3540

tctgtgcaca tcgttgaatg aagagagtct ttttgcacaa acttcacttg aaattgtgcc   3600

actgatgata aacggaatga gagccaaaaa agtttagttg gagacagttg taaattcaat   3660

ttggagttta tttaattgac ttttctatca cgttggggca catgccaact ccctggtttc   3720

ttcctggcat ggtgtttggg cagcaggcat cattttcctt ttctagcttc ataggaatat   3780

tgtgagctca ccatgctgtg gaggttggga aagagcagag tcttggctgc cctgctttct   3840

ccttaggact cttcactttt ctcaccacat ctcttgcatg acttcatggt actggggaca   3900

agtttgtatg ccttcacccc agagctggct gggttatggc ttttgtagca gagcccatac   3960

agcctatgga agaactagaa tctcactcac agtaataaga atctaggagg aattccaaac   4020

cgaagcaggc agggtctgga acccaaagga cagcattttc tacccacttc ttaatattga   4080

cagcttcccc gttctattta atgtccaaaa atgtttccca aaatttcaaa ctctttcact   4140

gtaaagattt gttacaaaga atgtggtttg gggaattacc ttattttata ttgttgtaaa   4200

caaacttcaa attctacatg tgcgactttt ctccttcctg aagggtgttt agtagtcagc   4260

gttttcagaa ttgttttgtt actatacttt aacattttac atttcctgtt tgtattattt   4320

tgtgagagca aggtgatcat gctgcttaag gtccaggtac aacctatttg taccttttga   4380

gacaatattt gtgttacttt tgcaggttac ggttccacat gtaattgcta tattttgttt   4440

tgtttttcct tactaggcaa agttaaaatg ttccatgctt tgaggagtga cccatttcac   4500

tactttgttt tcttatcact aaaggcaaaa atcaaagcac agttgtccat taacacttat   4560

aagttaatta tgggtttatg agtctgtaat gttatatgct gcaaacattt actatgtaaa   4620

cgtgaagtag ccaataatat ctcaatagta gtaacagtat ctttagcgac ctttggaata   4680

gttaagcaca ggtcattgtg gacatgaatt caggcctctg tactaaaatc tatttcaggg   4740

aatgttctgt ctagtgattt gctcaccatt tgatatataa tgaattatag gacaagtata   4800

agctgatctg ctatagctgt ccatcagaga gaatacacgt ggctataaca tctataacaa   4860

aacgacgatt cctctacaag aggctgtttc tcactgctaa cgttggtgtt tctggcgtgg   4920

gaagaaatgc acaggcgtgc atggcatgca cgttcagaca gctgcattgt aagagttctg   4980

tcatgcagtc tgaaaaggga agaaacagga tggctttctg tagccacacc tgtgaggcgt   5040

gatgattgtt gtattattag attactgatt tttcttttct gaaaatacat ttgagtttta   5100

atcacatctg tggaagctgt aacttttaag gtagtcaatt tcatgtcttg ttcaacgatg   5160

taagcagaaa ctgaattgcc ctaattttgc caactggcca ttattgggat tattgtttaa   5220

atttttggta aaggaagtaa tctcctttca ttcattgtga cttttgttct tagggaagca   5280

gagaagactc cccaagttct tataacctca ttgtgcttcc ctaatttaaa gccatgttga   5340

ggggctccat tcccaattcc tgggtcaagg tgaattaacc ctatgttgga gcactggaaa   5400

ccgttatttg caaacattgc tgttaccatt tagaaatatg tgcactatca gctgggtgca   5460

gtggctcacg tctgtaatcc cagcactttg ggaggccgag gcaggtggat cacctgaggt   5520

caggagttcg agaccagcct ggccaacagg gtgaaacccc gtctctacta aaagtacaaa   5580

aattagctgg gcgtggtggc ggacgcctgt aatctcagct acttgggagg ctgaagcagg   5640

agaggtgctg gaacctggga ggcggaggtt gaagtgagcc gagattgcgc tattgcactc   5700

cagctcgggc gacaactgca agactccatc tcaaaaaaat aaaaataaaa gaaaagaaag   5760

aaatatgtgc actacctaag ttttgtcttt agaaaaacta tccacctata aaaaattacc   5820

ttgacaaaaa tagttccggt ttgactaatc attttgtttc tttaagtggt aagtgtatgc   5880

aaggtggatc cttgatgagc caacattgca ctgtggatac atatctatgt ttacgcgcta   5940

ttagaacaga aggcgctgta tatagaaatg ttgctttgaa gcaatatttg caaaacacgc   6000

agacttctgt atctgtattt ggaaaaaata aaacaggttc ttgttgctat gtttcagtt    6059


<210>  10012
<211>  1012
<212>  PRT
<213>  Homo sapiens

<400>  10012

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val Lys Pro Lys Lys Lys 
    530                 535                 540


Lys Lys Lys Lys Lys Lys Thr Lys Pro Glu Cys Pro Cys Ser Glu Glu 
545                 550                 555                 560


Ile Ser Asp Thr Ser Gln Glu Pro Ser Pro Pro Lys Ala Phe Ala Val 
                565                 570                 575


Thr Arg Cys Gly Ser Ser His Lys Pro Gly Val His Met Ser Pro Gln 
            580                 585                 590


Leu His Gly Pro Glu Ser Gly His His Lys Gly Lys Val Lys Ala Leu 
        595                 600                 605


Glu Glu Asp Asn Leu Ser Glu Ser Ser Ser Glu Ser Phe Leu Trp Ser 
    610                 615                 620


Asp Asp Glu Tyr Gly Gln Asp Val Asp Val Thr Thr Asn Pro Asp Glu 
625                 630                 635                 640


Glu Leu Asp Gly Asp Asp Arg Tyr Asp Phe Glu Val Val Arg Cys Ile 
                645                 650                 655


Cys Glu Val Gln Glu Glu Asn Asp Phe Met Ile Gln Cys Glu Glu Cys 
            660                 665                 670


Gln Cys Trp Gln His Gly Val Cys Met Gly Leu Leu Glu Glu Asn Val 
        675                 680                 685


Pro Glu Lys Tyr Thr Cys Tyr Val Cys Gln Asp Pro Pro Gly Gln Arg 
    690                 695                 700


Pro Gly Phe Lys Tyr Trp Tyr Asp Lys Glu Trp Leu Ser Arg Gly His 
705                 710                 715                 720


Met His Gly Leu Ala Phe Leu Glu Glu Asn Tyr Ser His Gln Asn Ala 
                725                 730                 735


Lys Lys Ile Val Ala Thr His Gln Leu Leu Gly Asp Val Gln Arg Val 
            740                 745                 750


Ile Glu Val Leu His Gly Leu Gln Leu Lys Met Ser Ile Leu Gln Ser 
        755                 760                 765


Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln Pro Trp Lys Gln His 
    770                 775                 780


Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile Pro Val Thr Asp Thr 
785                 790                 795                 800


Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr Leu Asn Gly Ala Val 
                805                 810                 815


Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro Arg Ser Val Glu Glu 
            820                 825                 830


Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys Pro Arg Ala Tyr Tyr 
        835                 840                 845


Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr Arg Gly Ser Ala Leu 
    850                 855                 860


Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly Asp Asp Ser Leu Ser 
865                 870                 875                 880


Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg Ser Lys Gly Asp Ser 
                885                 890                 895


Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu Tyr Val Ser Lys Lys 
            900                 905                 910


Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu Leu Asp Arg Gly Gly 
        915                 920                 925


Glu Gly Leu Leu Ser Ser Gln His Gln Trp Gln Phe Asn Leu Leu Thr 
    930                 935                 940


His Val Glu Ser Leu Gln Asp Glu Val Thr His Arg Met Asp Ser Ile 
945                 950                 955                 960


Glu Lys Glu Leu Asp Val Leu Glu Ser Trp Leu Asp Tyr Thr Gly Glu 
                965                 970                 975


Leu Glu Pro Pro Glu Pro Leu Ala Arg Leu Pro Gln Leu Lys His Cys 
            980                 985                 990


Ile Lys Gln Leu Leu Met Asp Leu Gly Lys Val Gln Gln Ile Ala Leu 
        995                 1000                1005


Cys Cys Ser Thr 
    1010


<210>  10013
<211>  5950
<212>  DNA
<213>  Homo sapiens

<400>  10013
tgaggtggag tctcacttcg ttgcccaggc tagagtacaa tggtgcaatc tcggctcact     60

gcaacctctg cctcccggat tcaagtgatt ctcctgcttc agcctcccaa gtagctggta    120

ctacaggaga ataaaggcag ccccgttgat gactgaaaat gacaaagcat ccacctaaca    180

gacgaggaat cagctttgaa gtgggagccc agttggaagc ccgggaccgt ttaaaaaact    240

ggtatccagc tcacatagaa gacattgact acgaggaagg aaaagtactc atccatttca    300

agcgttggaa ccatcgttat gatgagtggt tctgctggga cagtccttat ttacgccctt    360

tagagaaaat acagctgagg aaagagggct tgcatgaaga ggatggatct tctgaatttc    420

aaataaatga gcaggtcctt gcttgctggt ctgattgtcg tttttacccg gccaaagtca    480

ctgctgttaa caaggatggt acttacactg tgaaatttta tgatggagta gttcagactg    540

tcaaacatat tcatgtcaaa gctttttcca aagatcagaa tattgtgggt aatgctaggc    600

ctaaagaaac agatcacaaa agtctttcat catctcctga taaacgagag aagtttaaag    660

aacagagaaa agcaacagtg aatgtgaaga aagacaaaga agataaaccc ttaaagacag    720

aaaagcgacc caagcagcct gataaagaag gaaagttaat ctgttctgaa aaggggaaag    780

tgtcagagaa aagtcttccc aagaacgaga aggaagacaa ggaaaacatt tccgaaaatg    840

acagagagta ttctggagat gcccaagtgg ataagaaacc tgaaaatgac attgtgaaga    900

gtccacaaga aaacttgagg gaacccaaaa gaaaacgagg cagaccccct tccatagctc    960

ctactgctgt ggattcaaac tctcaaactt tgcaaccaat aacattggaa ctgagaagaa   1020

ggaaaatatc aaaaggatgt gaagtcccat taaaacgtcc tcggcttgac aaaaattcat   1080

cccaggaaaa gtcaaaaaac tactcggaaa acactgacaa agacttatcg aggagacgtt   1140

cctccaggct gtccactaat gggacccatg agatcctaga tcctgacttg gttgtatcag   1200

atttggttga tacggatcct ttgcaagaca cgttgtctag taccaaggaa tctgaagaag   1260

gtcagttgaa gtctgctttg gaagctggcc aggtctcatc tgcactgact tgccactcct   1320

ttggggatgg atccggggct gcaggcttgg agttgaactg cccatcaatg ggagaaaaca   1380

cgatgaaaac agaaccgact tctccccttg tggaattaca agagatttcg actgtggaag   1440

taacaaatac ttttaagaaa acagatgatt ttgggtcatc taatgcacca gctgtcgacc   1500

tagaccataa gtttagatgc aaagttgtgg actgtttaaa atttttccgc aaagccaaac   1560

tgttgcacta tcacatgaag tatttccatg gaatggagaa gtcactggag ccagaagaga   1620

gcccgggaaa gaggcatgtc caaaccaggg gcccttcagc ttcagacaag cccagccagg   1680

agaccctgac caggaagcgg gtctctgcca gttccccaac tacaaaagac aaggaaaaga   1740

ataaagagaa gaaattcaag gagtttgtga gagtgaagcc aaagaagaaa aagaaaaaga   1800

aaaagaaaac caaacctgaa tgcccctgca gtgaggagat cagtgacacc tcccaggaac   1860

cttctccacc caaggcattt gctgttacca ggtgtgggtc ctcacacaag ccaggggtcc   1920

atatgagccc gcagcttcat ggcccagaat ctggacacca caaagggaaa gtgaaagcat   1980

tggaggagga taatttgagt gagtcctctt ctgagagctt tctctggagt gatgatgagt   2040

atggccaaga tgtggatgtg accaccaacc cagatgagga acttgatggg gatgaccgct   2100

atgacttcga ggtggtccgc tgcatctgtg aggtccagga ggaaaatgac ttcatgattc   2160

agtgtgaaga gtgccagtgc tggcagcatg gggtctgcat gggattactg gaagaaaatg   2220

tgcccgagaa atacacctgt tatgtttgcc aagaccctcc aggtcagagg cctggcttca   2280

agtactggta tgacaaggag tggctgagca ggggacatat gcatggcctg gcatttctag   2340

aagagaacta ctcccatcag aatgccaaga agatcgtggc cacccaccag cttcttggtg   2400

atgtgcagag agtgattgag gttctgcatg gcctgcagct caagatgagc atcttgcaaa   2460

gccgggagca tcctgatctg ccgctgtggt gccagccttg gaaacagcac tcaggggagg   2520

ggagatctca tttcagaaac atccctgtca ctgacaccag gagcaaggag gaagctccaa   2580

gctatagaac tttgaacggg gcagtggaga agcccaggcc cctggccctg cccctgccgc   2640

gttctgtgga ggaatcctat atcaccagtg agcattgcta ccagaagccc cgcgcctatt   2700

accctgccgt ggagcagaag ctggtggtgg agacgagggg ctctgccctc gacgatgcgg   2760

tcaaccccct ccatgagaac ggcgatgatt ccctttcccc gcgcctgggc tggcctctag   2820

accaagacag gagcaagggg gacagtgacc ccaaacccgg ctccccaaag gtgaaggaat   2880

atgtctccaa aaaggcccta ccagaagaag cccctgctcg gaagctgctg gacagaggtg   2940

gagaggggct gctgagctcc cagcaccagt ggcagtttaa cctgctgacc catgtggaat   3000

ctcttcagga tgaagttacg cacaggatgg actccattga gaaggagttg gatgtgttgg   3060

agagctggct ggactacact ggggaactgg agccccctga gccgctggcc aggcttccgc   3120

agctcaagca ttgtatcaag cagctgctga tggacctggg caaggtgcag cagatcgccc   3180

tctgctgctc aacatgaaac tgggcaccca aaactcatgg gggcacaatc ctggggcacc   3240

tgcaggagga gcttcgcata tttaaataaa taaacctagc atgctgaatg cacgtgacac   3300

cgactgactt cagggatctg ggccaggagt gtggtggaca ttggacaaag aggccatttt   3360

ggctgcggga ggacactctg atctcgaagc ctgccataaa ggtagcaaat agactcttgg   3420

gattcccctc ttctgtgcac atcgttgaat gaagagagtc tttttgcaca aacttcactt   3480

gaaattgtgc cactgatgat aaacggaatg agagccaaaa aagtttagtt ggagacagtt   3540

gtaaattcaa tttggagttt atttaattga cttttctatc acgttggggc acatgccaac   3600

tccctggttt cttcctggca tggtgtttgg gcagcaggca tcattttcct tttctagctt   3660

cataggaata ttgtgagctc accatgctgt ggaggttggg aaagagcaga gtcttggctg   3720

ccctgctttc tccttaggac tcttcacttt tctcaccaca tctcttgcat gacttcatgg   3780

tactggggac aagtttgtat gccttcaccc cagagctggc tgggttatgg cttttgtagc   3840

agagcccata cagcctatgg aagaactaga atctcactca cagtaataag aatctaggag   3900

gaattccaaa ccgaagcagg cagggtctgg aacccaaagg acagcatttt ctacccactt   3960

cttaatattg acagcttccc cgttctattt aatgtccaaa aatgtttccc aaaatttcaa   4020

actctttcac tgtaaagatt tgttacaaag aatgtggttt ggggaattac cttattttat   4080

attgttgtaa acaaacttca aattctacat gtgcgacttt tctccttcct gaagggtgtt   4140

tagtagtcag cgttttcaga attgttttgt tactatactt taacatttta catttcctgt   4200

ttgtattatt ttgtgagagc aaggtgatca tgctgcttaa ggtccaggta caacctattt   4260

gtaccttttg agacaatatt tgtgttactt ttgcaggtta cggttccaca tgtaattgct   4320

atattttgtt ttgtttttcc ttactaggca aagttaaaat gttccatgct ttgaggagtg   4380

acccatttca ctactttgtt ttcttatcac taaaggcaaa aatcaaagca cagttgtcca   4440

ttaacactta taagttaatt atgggtttat gagtctgtaa tgttatatgc tgcaaacatt   4500

tactatgtaa acgtgaagta gccaataata tctcaatagt agtaacagta tctttagcga   4560

cctttggaat agttaagcac aggtcattgt ggacatgaat tcaggcctct gtactaaaat   4620

ctatttcagg gaatgttctg tctagtgatt tgctcaccat ttgatatata atgaattata   4680

ggacaagtat aagctgatct gctatagctg tccatcagag agaatacacg tggctataac   4740

atctataaca aaacgacgat tcctctacaa gaggctgttt ctcactgcta acgttggtgt   4800

ttctggcgtg ggaagaaatg cacaggcgtg catggcatgc acgttcagac agctgcattg   4860

taagagttct gtcatgcagt ctgaaaaggg aagaaacagg atggctttct gtagccacac   4920

ctgtgaggcg tgatgattgt tgtattatta gattactgat ttttcttttc tgaaaataca   4980

tttgagtttt aatcacatct gtggaagctg taacttttaa ggtagtcaat ttcatgtctt   5040

gttcaacgat gtaagcagaa actgaattgc cctaattttg ccaactggcc attattggga   5100

ttattgttta aatttttggt aaaggaagta atctcctttc attcattgtg acttttgttc   5160

ttagggaagc agagaagact ccccaagttc ttataacctc attgtgcttc cctaatttaa   5220

agccatgttg aggggctcca ttcccaattc ctgggtcaag gtgaattaac cctatgttgg   5280

agcactggaa accgttattt gcaaacattg ctgttaccat ttagaaatat gtgcactatc   5340

agctgggtgc agtggctcac gtctgtaatc ccagcacttt gggaggccga ggcaggtgga   5400

tcacctgagg tcaggagttc gagaccagcc tggccaacag ggtgaaaccc cgtctctact   5460

aaaagtacaa aaattagctg ggcgtggtgg cggacgcctg taatctcagc tacttgggag   5520

gctgaagcag gagaggtgct ggaacctggg aggcggaggt tgaagtgagc cgagattgcg   5580

ctattgcact ccagctcggg cgacaactgc aagactccat ctcaaaaaaa taaaaataaa   5640

agaaaagaaa gaaatatgtg cactacctaa gttttgtctt tagaaaaact atccacctat   5700

aaaaaattac cttgacaaaa atagttccgg tttgactaat cattttgttt ctttaagtgg   5760

taagtgtatg caaggtggat ccttgatgag ccaacattgc actgtggata catatctatg   5820

tttacgcgct attagaacag aaggcgctgt atatagaaat gttgctttga agcaatattt   5880

gcaaaacacg cagacttctg tatctgtatt tggaaaaaat aaaacaggtt cttgttgcta   5940

tgtttcagtt                                                          5950


<210>  10014
<211>  1012
<212>  PRT
<213>  Homo sapiens

<400>  10014

Met Thr Lys His Pro Pro Asn Arg Arg Gly Ile Ser Phe Glu Val Gly 
1               5                   10                  15


Ala Gln Leu Glu Ala Arg Asp Arg Leu Lys Asn Trp Tyr Pro Ala His 
            20                  25                  30


Ile Glu Asp Ile Asp Tyr Glu Glu Gly Lys Val Leu Ile His Phe Lys 
        35                  40                  45


Arg Trp Asn His Arg Tyr Asp Glu Trp Phe Cys Trp Asp Ser Pro Tyr 
    50                  55                  60


Leu Arg Pro Leu Glu Lys Ile Gln Leu Arg Lys Glu Gly Leu His Glu 
65                  70                  75                  80


Glu Asp Gly Ser Ser Glu Phe Gln Ile Asn Glu Gln Val Leu Ala Cys 
                85                  90                  95


Trp Ser Asp Cys Arg Phe Tyr Pro Ala Lys Val Thr Ala Val Asn Lys 
            100                 105                 110


Asp Gly Thr Tyr Thr Val Lys Phe Tyr Asp Gly Val Val Gln Thr Val 
        115                 120                 125


Lys His Ile His Val Lys Ala Phe Ser Lys Asp Gln Asn Ile Val Gly 
    130                 135                 140


Asn Ala Arg Pro Lys Glu Thr Asp His Lys Ser Leu Ser Ser Ser Pro 
145                 150                 155                 160


Asp Lys Arg Glu Lys Phe Lys Glu Gln Arg Lys Ala Thr Val Asn Val 
                165                 170                 175


Lys Lys Asp Lys Glu Asp Lys Pro Leu Lys Thr Glu Lys Arg Pro Lys 
            180                 185                 190


Gln Pro Asp Lys Glu Gly Lys Leu Ile Cys Ser Glu Lys Gly Lys Val 
        195                 200                 205


Ser Glu Lys Ser Leu Pro Lys Asn Glu Lys Glu Asp Lys Glu Asn Ile 
    210                 215                 220


Ser Glu Asn Asp Arg Glu Tyr Ser Gly Asp Ala Gln Val Asp Lys Lys 
225                 230                 235                 240


Pro Glu Asn Asp Ile Val Lys Ser Pro Gln Glu Asn Leu Arg Glu Pro 
                245                 250                 255


Lys Arg Lys Arg Gly Arg Pro Pro Ser Ile Ala Pro Thr Ala Val Asp 
            260                 265                 270


Ser Asn Ser Gln Thr Leu Gln Pro Ile Thr Leu Glu Leu Arg Arg Arg 
        275                 280                 285


Lys Ile Ser Lys Gly Cys Glu Val Pro Leu Lys Arg Pro Arg Leu Asp 
    290                 295                 300


Lys Asn Ser Ser Gln Glu Lys Ser Lys Asn Tyr Ser Glu Asn Thr Asp 
305                 310                 315                 320


Lys Asp Leu Ser Arg Arg Arg Ser Ser Arg Leu Ser Thr Asn Gly Thr 
                325                 330                 335


His Glu Ile Leu Asp Pro Asp Leu Val Val Ser Asp Leu Val Asp Thr 
            340                 345                 350


Asp Pro Leu Gln Asp Thr Leu Ser Ser Thr Lys Glu Ser Glu Glu Gly 
        355                 360                 365


Gln Leu Lys Ser Ala Leu Glu Ala Gly Gln Val Ser Ser Ala Leu Thr 
    370                 375                 380


Cys His Ser Phe Gly Asp Gly Ser Gly Ala Ala Gly Leu Glu Leu Asn 
385                 390                 395                 400


Cys Pro Ser Met Gly Glu Asn Thr Met Lys Thr Glu Pro Thr Ser Pro 
                405                 410                 415


Leu Val Glu Leu Gln Glu Ile Ser Thr Val Glu Val Thr Asn Thr Phe 
            420                 425                 430


Lys Lys Thr Asp Asp Phe Gly Ser Ser Asn Ala Pro Ala Val Asp Leu 
        435                 440                 445


Asp His Lys Phe Arg Cys Lys Val Val Asp Cys Leu Lys Phe Phe Arg 
    450                 455                 460


Lys Ala Lys Leu Leu His Tyr His Met Lys Tyr Phe His Gly Met Glu 
465                 470                 475                 480


Lys Ser Leu Glu Pro Glu Glu Ser Pro Gly Lys Arg His Val Gln Thr 
                485                 490                 495


Arg Gly Pro Ser Ala Ser Asp Lys Pro Ser Gln Glu Thr Leu Thr Arg 
            500                 505                 510


Lys Arg Val Ser Ala Ser Ser Pro Thr Thr Lys Asp Lys Glu Lys Asn 
        515                 520                 525


Lys Glu Lys Lys Phe Lys Glu Phe Val Arg Val Lys Pro Lys Lys Lys 
    530                 535                 540


Lys Lys Lys Lys Lys Lys Thr Lys Pro Glu Cys Pro Cys Ser Glu Glu 
545                 550                 555                 560


Ile Ser Asp Thr Ser Gln Glu Pro Ser Pro Pro Lys Ala Phe Ala Val 
                565                 570                 575


Thr Arg Cys Gly Ser Ser His Lys Pro Gly Val His Met Ser Pro Gln 
            580                 585                 590


Leu His Gly Pro Glu Ser Gly His His Lys Gly Lys Val Lys Ala Leu 
        595                 600                 605


Glu Glu Asp Asn Leu Ser Glu Ser Ser Ser Glu Ser Phe Leu Trp Ser 
    610                 615                 620


Asp Asp Glu Tyr Gly Gln Asp Val Asp Val Thr Thr Asn Pro Asp Glu 
625                 630                 635                 640


Glu Leu Asp Gly Asp Asp Arg Tyr Asp Phe Glu Val Val Arg Cys Ile 
                645                 650                 655


Cys Glu Val Gln Glu Glu Asn Asp Phe Met Ile Gln Cys Glu Glu Cys 
            660                 665                 670


Gln Cys Trp Gln His Gly Val Cys Met Gly Leu Leu Glu Glu Asn Val 
        675                 680                 685


Pro Glu Lys Tyr Thr Cys Tyr Val Cys Gln Asp Pro Pro Gly Gln Arg 
    690                 695                 700


Pro Gly Phe Lys Tyr Trp Tyr Asp Lys Glu Trp Leu Ser Arg Gly His 
705                 710                 715                 720


Met His Gly Leu Ala Phe Leu Glu Glu Asn Tyr Ser His Gln Asn Ala 
                725                 730                 735


Lys Lys Ile Val Ala Thr His Gln Leu Leu Gly Asp Val Gln Arg Val 
            740                 745                 750


Ile Glu Val Leu His Gly Leu Gln Leu Lys Met Ser Ile Leu Gln Ser 
        755                 760                 765


Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln Pro Trp Lys Gln His 
    770                 775                 780


Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile Pro Val Thr Asp Thr 
785                 790                 795                 800


Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr Leu Asn Gly Ala Val 
                805                 810                 815


Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro Arg Ser Val Glu Glu 
            820                 825                 830


Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys Pro Arg Ala Tyr Tyr 
        835                 840                 845


Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr Arg Gly Ser Ala Leu 
    850                 855                 860


Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly Asp Asp Ser Leu Ser 
865                 870                 875                 880


Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg Ser Lys Gly Asp Ser 
                885                 890                 895


Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu Tyr Val Ser Lys Lys 
            900                 905                 910


Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu Leu Asp Arg Gly Gly 
        915                 920                 925


Glu Gly Leu Leu Ser Ser Gln His Gln Trp Gln Phe Asn Leu Leu Thr 
    930                 935                 940


His Val Glu Ser Leu Gln Asp Glu Val Thr His Arg Met Asp Ser Ile 
945                 950                 955                 960


Glu Lys Glu Leu Asp Val Leu Glu Ser Trp Leu Asp Tyr Thr Gly Glu 
                965                 970                 975


Leu Glu Pro Pro Glu Pro Leu Ala Arg Leu Pro Gln Leu Lys His Cys 
            980                 985                 990


Ile Lys Gln Leu Leu Met Asp Leu Gly Lys Val Gln Gln Ile Ala Leu 
        995                 1000                1005


Cys Cys Ser Thr 
    1010


<210>  10015
<211>  540
<212>  DNA
<213>  Homo sapiens

<400>  10015
gtagagacgg ggtttcacca tgttggctag gattgtctcg atctcttgac cttgtgatcc     60

tcccacctcg acctcccaaa gtgctgggac tacaggcatg agccactgcg cctagcctgg    120

aatgggttgt ttaatagata gcttattgtc cttcacatgt ataatccttt acattataca    180

cttgtgaaaa attttcattg tgaaaaacta aaatttagga aagtatttaa gaagaaagga    240

acaatcacca ataacctata acttattttt ttcttcctcc caaagttctg ggattatagg    300

catgagccac catgcctggc cttttttttt tgtttttgtt ttttaaagag acaggttctt    360

gctctgtcac tcaggctgga gtacagtggc acaatcataa ctcactgcag tctcaacctc    420

ctgggctcaa gcgatcctcc tgcctcagcc ttttcagtag ctgggattat aagcctgagc    480

cacctcatct ggctgtgtat gagttttaat gtgagctcca tgtggtacaa ttttgcatcc    540


<210>  10016
<211>  65
<212>  PRT
<213>  Homo sapiens

<400>  10016

Met Pro Gly Leu Phe Phe Leu Phe Leu Phe Phe Lys Glu Thr Gly Ser 
1               5                   10                  15


Cys Ser Val Thr Gln Ala Gly Val Gln Trp His Asn His Asn Ser Leu 
            20                  25                  30


Gln Ser Gln Pro Pro Gly Leu Lys Arg Ser Ser Cys Leu Ser Leu Phe 
        35                  40                  45


Ser Ser Trp Asp Tyr Lys Pro Glu Pro Pro His Leu Ala Val Tyr Glu 
    50                  55                  60


Phe 
65


<210>  10017
<211>  2068
<212>  DNA
<213>  Homo sapiens

<400>  10017
tagtaaacat attccattcc ctcccaaact ttcctcatgc ccctttttag ttcctccttc     60

ccacctctcc cctccccctg agctccaggc aaccactatt ctgcttactg ttacttgtgg    120

tgtgttttct ctcttttttc ttcccccccg agatggagtc gctgtgttgc ccaggctgga    180

gtgaagtggc acgatctcaa ctcactacaa cctctgcctc ctgggctcaa gcgattctcc    240

tgcctcagcc tcccaagtag ctgggattac aggcatgagc caccacaccc agctaatttt    300

tgtattttta gtacagatgg ggttttatcg tattggtcat gctggtcttg aactcctgac    360

cccagctgat ctgcctacct tggcctccca aagtgctggg agtgagccag catgcccaga    420

tggtttgttt tcattttgca gactattgta gaaatggaat cctgcagtgc gcacttgttt    480

tgtctggctc ctttcaccca gcatactttg agattcactt atgttgctgt tcgtaccttt    540

ttttctattt ttattttttg agacggagtc ttgcactgtc gcccaggctg gagtgcagtg    600

gccagacctc agctcactgc aagctccgcc tcctgggttc acgccattct cctgcctcag    660

cctccccagt agctgggact acaggcgccc gctaccacgc ccggctaatt ttttctgtat    720

ttttagtaga gacagggttt taccatgtta gccaggatgg tctcaatctc ctgacctcgt    780

gatccgcccg ccttggcctc ccaaagtgct gggattaccg gcatgagcca ctgcgcccgg    840

cctgctgttc ctacctttat tgctgaaaag tcttccattg tgtggataca tcatgaatta    900

tttgtacatt cacttgatgg acatttgggc agttttcagt ttggggcgat tacaactaaa    960

actgctatga gtcttcatgt ataagtctct atgtggacgt aagtgatgct ttctcttgaa   1020

tgaatatgtt gtagtggatg gcaaggtcat aggatatatg tacgtataaa ctcttgttga   1080

tatctaaaaa gtaaggcatg gtgaattact tgaaatccta taaatatatt tggtaagaga   1140

agaagaaacg actggatttt tttgtttgtt tgttttggag acagattccc actctgtcac   1200

ccaggctgga gtgcaatggt gcgatctggg ctcactgcaa cctccgcctc cccgattcga   1260

gcaattcttc tgcctcagcc tcccaagtag ctgggattac aggcatctgc caccacgcct   1320

gactaatttt tatattttta gtagagacgg ggttttgcca tgtgggccag gctgatctca   1380

agctcctgac ctcaggtgat tcacctgcct tggcctccca aagtgctggg attacaggca   1440

tgagccaccg tgcccggcta cgactgaatt tttctttctt tctttttttt ttttttcttt   1500

gagatggagt ctcgctctgt cgccaggttg cagtgagctg agatcgcgcc actgcactcc   1560

agcctgggtg acatggcgat gaaaacaaca aaaatcagat ccccaggtga ttccagtatg   1620

tagccagggt tgaggagcag tgatctaagt agagttttgc aaacttgtct gtaaagggcc   1680

agataataaa tacttttcaa ccttggggtt gaaaggtctc tgtcctcact tttcagctct   1740

gctgttgaag tgtgaaagac acgtaaccaa tgaacatggc atgtttcact aaaatccatt   1800

tacaatgacg ggccatgggc cagagtgtgc tgagctggac tgaaaggcta agtgatggag   1860

gcgtggctct gcctccagac tggagcaatc tgctccagac ttcccaggca gagccagacc   1920

catcggacat gcttgcttag gagaagaata agcaccccag cattgaaaac aaaatgttaa   1980

aatgccaaca tttgtgttta attctagcta caaaagacaa ggaaaagaat aaagagaaga   2040

aattcaagga gtttgtgaga gtgaagcc                                      2068


<210>  10018
<211>  120
<212>  PRT
<213>  Homo sapiens

<400>  10018

Met Val Cys Phe His Phe Ala Asp Tyr Cys Arg Asn Gly Ile Leu Gln 
1               5                   10                  15


Cys Ala Leu Val Leu Ser Gly Ser Phe His Pro Ala Tyr Phe Glu Ile 
            20                  25                  30


His Leu Cys Cys Cys Ser Tyr Leu Phe Phe Tyr Phe Tyr Phe Leu Arg 
        35                  40                  45


Arg Ser Leu Ala Leu Ser Pro Arg Leu Glu Cys Ser Gly Gln Thr Ser 
    50                  55                  60


Ala His Cys Lys Leu Arg Leu Leu Gly Ser Arg His Ser Pro Ala Ser 
65                  70                  75                  80


Ala Ser Pro Val Ala Gly Thr Thr Gly Ala Arg Tyr His Ala Arg Leu 
                85                  90                  95


Ile Phe Ser Val Phe Leu Val Glu Thr Gly Phe Tyr His Val Ser Gln 
            100                 105                 110


Asp Gly Leu Asn Leu Leu Thr Ser 
        115                 120


<210>  10019
<211>  543
<212>  DNA
<213>  Homo sapiens

<400>  10019
aattgagaac ccctgcaatg gtgccagtta ctccaaagcc catgtcctct ttgtcctctc     60

aacagaagcc gggagcatcc tgatctgccg ctgtggtgcc agccttggaa acagcactca    120

ggggagggga gatctcattt cagaaacatc cctgtcactg acaccaggag caaggaggaa    180

gctccaagct atagaacttt gaacggggca gtggagaagc ccaggcccct ggccctgccc    240

ctgccgcgtt ctgtggagga atcctatatc accagtgagc attgctacca gaagccccgc    300

gcctattacc ctgccgtgga gcagaagctg gtggtggaga cgaggggctc tgccctcgac    360

gatgcggtca accccctcca tgagaacggc gatgattccc tttccccgcg cctgggctgg    420

cctctagacc aagacaggag caagggggac agtgacccca aacccggctc cccaaaggtg    480

aaggaatatg tctccaaaaa ggccctacca gaagaagccc ctgctcggaa gctgctggac    540

aga                                                                  543


<210>  10020
<211>  178
<212>  PRT
<213>  Homo sapiens

<400>  10020

Glu Pro Leu Gln Trp Cys Gln Leu Leu Gln Ser Pro Cys Pro Leu Cys 
1               5                   10                  15


Pro Leu Asn Arg Ser Arg Glu His Pro Asp Leu Pro Leu Trp Cys Gln 
            20                  25                  30


Pro Trp Lys Gln His Ser Gly Glu Gly Arg Ser His Phe Arg Asn Ile 
        35                  40                  45


Pro Val Thr Asp Thr Arg Ser Lys Glu Glu Ala Pro Ser Tyr Arg Thr 
    50                  55                  60


Leu Asn Gly Ala Val Glu Lys Pro Arg Pro Leu Ala Leu Pro Leu Pro 
65                  70                  75                  80


Arg Ser Val Glu Glu Ser Tyr Ile Thr Ser Glu His Cys Tyr Gln Lys 
                85                  90                  95


Pro Arg Ala Tyr Tyr Pro Ala Val Glu Gln Lys Leu Val Val Glu Thr 
            100                 105                 110


Arg Gly Ser Ala Leu Asp Asp Ala Val Asn Pro Leu His Glu Asn Gly 
        115                 120                 125


Asp Asp Ser Leu Ser Pro Arg Leu Gly Trp Pro Leu Asp Gln Asp Arg 
    130                 135                 140


Ser Lys Gly Asp Ser Asp Pro Lys Pro Gly Ser Pro Lys Val Lys Glu 
145                 150                 155                 160


Tyr Val Ser Lys Lys Ala Leu Pro Glu Glu Ala Pro Ala Arg Lys Leu 
                165                 170                 175


Leu Asp 



<210>  10021
<211>  902
<212>  DNA
<213>  Homo sapiens

<400>  10021
cacgcgcagc tcgccctccc gcaccgcgag ggcagcagcc gcctcatgcg actcgagaac     60

gctagagggc gccgcttccg ggagcccgca agcggcttcc gggtgctcgc gcgccgacct    120

ggacgcagag aagccagaga ctttcgcttc cggctgccgc aggcgcttcg ctggtgcaga    180

cgcagtgctg agcacacagc taccggacaa agagtgacgc ccggagctgg agttatggcg    240

gctacggagc cgatcttggc ggccactggg agtcccgcgg cggtgccacc ggagaaactg    300

gaaggagccg gttcgagctc agcccctgag cgtaactgtg tgggctcctc gctgccagag    360

gcctcaccgc ctgcccctga gccttccagt cccaacgccg cggtccctga agccatccct    420

acgccccgag ctgcggcctc cgcggccctg gagctgcctc tcgggcccgc acccgtgagc    480

gtagcgcctc aggccgaagc tgaagcgcgc tccacaccag gccccgccgg ctctagactc    540

ggtcccgaga cgttccgcca gcgtttccgg cagttccgct accaggatgc ggcgggtccc    600

cgggaggctt tccggcagct gcgggagctg tcccgccagt ggctgcggcc tgacatccgc    660

accaaggagc agatcgtgga gatgctggtg caagagcagc tgctcgccat cctgcccgag    720

gcggctcggg cccggcggat ccgccgccgc acggatgtgc gcatcactgg ctgagcggtg    780

gagctgcggg cggccagggc cgggcgctct gtgcggactg gggccatgat cgggcccggg    840

ggcctgagcc tgggacccca ccccgtgtta atgaaaaatg agttttggca gcgcctgtgg    900

tc                                                                   902


<210>  10022
<211>  242
<212>  PRT
<213>  Homo sapiens

<400>  10022

Met Arg Leu Glu Asn Ala Arg Gly Arg Arg Phe Arg Glu Pro Ala Ser 
1               5                   10                  15


Gly Phe Arg Val Leu Ala Arg Arg Pro Gly Arg Arg Glu Ala Arg Asp 
            20                  25                  30


Phe Arg Phe Arg Leu Pro Gln Ala Leu Arg Trp Cys Arg Arg Ser Ala 
        35                  40                  45


Glu His Thr Ala Thr Gly Gln Arg Val Thr Pro Gly Ala Gly Val Met 
    50                  55                  60


Ala Ala Thr Glu Pro Ile Leu Ala Ala Thr Gly Ser Pro Ala Ala Val 
65                  70                  75                  80


Pro Pro Glu Lys Leu Glu Gly Ala Gly Ser Ser Ser Ala Pro Glu Arg 
                85                  90                  95


Asn Cys Val Gly Ser Ser Leu Pro Glu Ala Ser Pro Pro Ala Pro Glu 
            100                 105                 110


Pro Ser Ser Pro Asn Ala Ala Val Pro Glu Ala Ile Pro Thr Pro Arg 
        115                 120                 125


Ala Ala Ala Ser Ala Ala Leu Glu Leu Pro Leu Gly Pro Ala Pro Val 
    130                 135                 140


Ser Val Ala Pro Gln Ala Glu Ala Glu Ala Arg Ser Thr Pro Gly Pro 
145                 150                 155                 160


Ala Gly Ser Arg Leu Gly Pro Glu Thr Phe Arg Gln Arg Phe Arg Gln 
                165                 170                 175


Phe Arg Tyr Gln Asp Ala Ala Gly Pro Arg Glu Ala Phe Arg Gln Leu 
            180                 185                 190


Arg Glu Leu Ser Arg Gln Trp Leu Arg Pro Asp Ile Arg Thr Lys Glu 
        195                 200                 205


Gln Ile Val Glu Met Leu Val Gln Glu Gln Leu Leu Ala Ile Leu Pro 
    210                 215                 220


Glu Ala Ala Arg Ala Arg Arg Ile Arg Arg Arg Thr Asp Val Arg Ile 
225                 230                 235                 240


Thr Gly 



<210>  10023
<211>  1149
<212>  DNA
<213>  Homo sapiens

<400>  10023
tttagagttc acttattaaa tgctgacgtt aacagaaccc acagagccgc atttcccttg     60

gtttcggagg acacgcgaaa aataacaaca gcaaagggtt ctcgagcatc tccttcgcgc    120

cagacggtgt gttgtacttt gtcatcgtcg cagtaaggcc ggtgctatcg ccctcctagt    180

ttgaccaagc gagaggactt tctccagatg ggcccctccc gagagaatgg tcgccgtccc    240

gctctcctgt tcgggtcacc accggccggg cgccactcga acgagccccg gccagccgtc    300

accctaatca ttcccgaagg aggggccatc agagctacag ctcatcaggg tcaatcagaa    360

ggggcgcccg cacgcaaagg tcacctactt tcgcttccgg ctgccgcagg cgcttcgctg    420

gtgcagacgc agtgctgagc acacagctac cggacaaaga gtgacgcccg gagctggagt    480

tatggcggct acggagccga tcttggcggc cactgggagt cccgcggcgg tgccaccgga    540

gaaactggaa ggagccggtt cgagctcagc ccctgagcgt aactgtgtgg gctcctcgct    600

gccagaggcc tcaccgcctg cccctgagcc ttccagtccc aacgccgcgg tccctgaagc    660

catccctacg ccccgagctg cggcctccgc ggccctggag ctgcctctcg ggcccgcacc    720

cgtgagcgta gcgcctcagg ccgaagctga agcgcgctcc acaccaggcc ccgccggctc    780

tagactcggt cccgagacgt tccgccagcg tttccggcag ttccgctacc aggatgcggc    840

gggtccccgg gaggctttcc ggcagctgcg ggagctgtcc cgccagtggc tgcggcctga    900

catccgcacc aaggagcaga tcgtggagat gctggtgcaa gagcagctgc tcgccatcct    960

gcccgaggcg gctcgggccc ggcggatccg ccgccgcacg gatgtgcgca tcactggctg   1020

agcggtggag ctgcgggcgg ccagggccgg gcgctctgtg cggactgggg ccatgatcgg   1080

gcccgggggc ctgagcctgg gaccccaccc cgtgttaatg aaaaatgagt tttggcagcg   1140

cctgtggtc                                                           1149


<210>  10024
<211>  76
<212>  PRT
<213>  Homo sapiens

<400>  10024

Met Gly Pro Ser Arg Glu Asn Gly Arg Arg Pro Ala Leu Leu Phe Gly 
1               5                   10                  15


Ser Pro Pro Ala Gly Arg His Ser Asn Glu Pro Arg Pro Ala Val Thr 
            20                  25                  30


Leu Ile Ile Pro Glu Gly Gly Ala Ile Arg Ala Thr Ala His Gln Gly 
        35                  40                  45


Gln Ser Glu Gly Ala Pro Ala Arg Lys Gly His Leu Leu Ser Leu Pro 
    50                  55                  60


Ala Ala Ala Gly Ala Ser Leu Val Gln Thr Gln Cys 
65                  70                  75


<210>  10025
<211>  1739
<212>  DNA
<213>  Homo sapiens

<400>  10025
gtgacttgct cctccttgtc ttccaccacg attgtgaggc ctccctagcc acgtggagct     60

ctcaaaggtg gagacaaccc aaatgtcctt caatggatgg ttaaatatac catggtacat    120

ctataccata gattactact cagcaataaa aaggacaaac tattgataca agcaaccact    180

tgggtgaatc tccagggaat tgtgccaagt ggaaagagcc aagcccaaat gattatacac    240

tatatgattc cagaacccac agagccgcat ttcccttggt ttcggaggac acgcgaaaaa    300

taacaacagc aaagggttct cgagcatctc cttcgcgcca gacggtgtgt tgtactttgt    360

catcgtcgca gtaaggccgg tgctatcgcc ctcctagttt gaccaagcga gaggactttc    420

tccagatggg cccctcccga gagaatggtc gccgtcccgc tctcctgttc gggtcaccac    480

cggccgggcg ccactcgaac gagccccggc cagccgtcac cctaatcatt cccgaaggag    540

gggccatcag agctacagct catcagggtc aatcagaagg ggcgcccgca cgcaaaggtc    600

acctgcaaac cgaagcggcg cacggataag gtccgggact tgaagtctat ctccaaacat    660

tcaggctcct cctccgactc ctcctcgaac tggcgctcag aggcgccacc attcggaagg    720

agcccaggcc acgcgcagct cgccctcccg caccgcgagg gcagcagccg cctcatgcga    780

ctcgagaacg ctagagggcg ccgcttccgg gagcccgcaa gcggcttccg ggtgctcgcg    840

cgccgacctg gacgcagaga agccagagac tttcgcttcc ggctgccgca ggcgcttcgc    900

tggtgcaggt aagctccgca cactctcggc cggtcccgag tccgactccc tcaagggtga    960

cgcgagctct gccctttaac cggaaacgtc tccctgctca ccccaccccc gcgcagacgc   1020

agtgctgagc acacagctac cggacaaaga gtgacgcccg gagctggagt tatggcggct   1080

acggagccga tcttggcggc cactgggagt cccgcggcgg tgccaccgga gaaactggaa   1140

ggagccggtt cgagctcagc ccctgagcgt aactgtgtgg gctcctcgct gccagaggcc   1200

tcaccgcctg cccctgagcc ttccagtccc aacgccgcgg tccctgaagc catccctacg   1260

ccccgagctg cggcctccgc ggccctggag ctgcctctcg ggcccgcacc cgtgagcgta   1320

gcgcctcagg ccgaagctga agcgcgctcc acaccaggcc ccgccggctc tagactcggt   1380

cccgagacgt tccgccagcg tttccggcag ttccgctacc aggatgcggc gggtccccgg   1440

gaggctttcc ggcagctgcg ggagctgtcc cgccagtggc tgcggcctga catccgcacc   1500

aaggagcaga tcgtggagat gctggtgcaa gagcagctgc tcgccatcct gcccgaggcg   1560

gctcgggccc ggcggatccg ccgccgcacg gatgtgcgca tcactggctg agcggtggag   1620

ctgcgggcgg ccagggccgg gcgctctgtg cggactgggg ccatgatcgg gcccgggggc   1680

ctgagcctgg gaccccaccc cgtgttaatg aaaaatgagt tttggcagcg cctgtggtc    1739


<210>  10026
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  10026

Met Val Lys Tyr Thr Met Val His Leu Tyr His Arg Leu Leu Leu Ser 
1               5                   10                  15


Asn Lys Lys Asp Lys Leu Leu Ile Gln Ala Thr Thr Trp Val Asn Leu 
            20                  25                  30


Gln Gly Ile Val Pro Ser Gly Lys Ser Gln Ala Gln Met Ile Ile His 
        35                  40                  45


Tyr Met Ile Pro Glu Pro Thr Glu Pro His Phe Pro Trp Phe Arg Arg 
    50                  55                  60


Thr Arg Glu Lys 
65


<210>  10027
<211>  387
<212>  DNA
<213>  Homo sapiens

<400>  10027
ggctgccgca ggcgcttcgc tggtgcagac gcagtgctga gcacacagct accggacaaa     60

gagtgacgcc cggagctgga gttatggcgg ctacggagcc gatcttggcg ctgcgggagc    120

tgtcccgcca gtggctgcgg cctgacatcc gcaccaagga gcagatcgtg gagatgctgg    180

tgcaagagca gctgctcgcc atcctgcccg aggcggctcg ggcccggcgg atccgccgcc    240

gcacggatgt gcgcatcact ggctgagcgg tggagctgcg ggcggccagg gccgggcgct    300

ctgtgcggac tggggccatg atcgggcccg ggggcctgag cctgggaccc caccccgtgt    360

taatgaaaaa tgagttttgg cagcgcc                                        387


<210>  10028
<211>  60
<212>  PRT
<213>  Homo sapiens

<400>  10028

Met Ala Ala Thr Glu Pro Ile Leu Ala Leu Arg Glu Leu Ser Arg Gln 
1               5                   10                  15


Trp Leu Arg Pro Asp Ile Arg Thr Lys Glu Gln Ile Val Glu Met Leu 
            20                  25                  30


Val Gln Glu Gln Leu Leu Ala Ile Leu Pro Glu Ala Ala Arg Ala Arg 
        35                  40                  45


Arg Ile Arg Arg Arg Thr Asp Val Arg Ile Thr Gly 
    50                  55                  60


<210>  10029
<211>  703
<212>  DNA
<213>  Homo sapiens

<400>  10029
agagactttc gcttccggct gccgcaggcg cttcgctggt gcaggtaagc tccgcacact     60

ctcggccggt cccgagtccg actccctcaa gggtgacgcg agctctgccc tttaaccgga    120

aacgtctccc tgctcacccc acccccgcgc agacgcagtg ctgagcacac agctaccgga    180

caaagagtga cgcccggagc tggagttatg gcggctacgg agccgatctt ggcggccact    240

gggagtcccg cggcggtgcc accggagaaa ctggaaggag ccggttcgag ctcagcccct    300

gagcgtaact gtgtgggctc ctcgctgcca gaggcctcac cgcctgcccc tgagccttcc    360

agtcccaacg ccgcggtccc tgaagccatc cctacgcccc gagctgcggc ctccgcggcc    420

ctggagctgc ctctcgggcc cgcacccgtg agcgtagcgc ctcaggccga agctgaagcg    480

cgctccacac caggccccgc cggctctaga ctcggtcccg agacgttccg ccagcgtttc    540

cggcagatcc gccgccgcac ggatgtgcgc atcactggct gagcggtgga gctgcgggcg    600

gccagggccg ggcgctctgt gcggactggg gccatgatcg ggcccggggg cctgagcctg    660

ggaccccacc ccgtgttaat gaaaaatgag ttttggcagc gcc                      703


<210>  10030
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  10030

Met Ala Ala Thr Glu Pro Ile Leu Ala Ala Thr Gly Ser Pro Ala Ala 
1               5                   10                  15


Val Pro Pro Glu Lys Leu Glu Gly Ala Gly Ser Ser Ser Ala Pro Glu 
            20                  25                  30


Arg Asn Cys Val Gly Ser Ser Leu Pro Glu Ala Ser Pro Pro Ala Pro 
        35                  40                  45


Glu Pro Ser Ser Pro Asn Ala Ala Val Pro Glu Ala Ile Pro Thr Pro 
    50                  55                  60


Arg Ala Ala Ala Ser Ala Ala Leu Glu Leu Pro Leu Gly Pro Ala Pro 
65                  70                  75                  80


Val Ser Val Ala Pro Gln Ala Glu Ala Glu Ala Arg Ser Thr Pro Gly 
                85                  90                  95


Pro Ala Gly Ser Arg Leu Gly Pro Glu Thr Phe Arg Gln Arg Phe Arg 
            100                 105                 110


Gln Ile Arg Arg Arg Thr Asp Val Arg Ile Thr Gly 
        115                 120


<210>  10031
<211>  658
<212>  DNA
<213>  Homo sapiens

<400>  10031
agagactttc gcttccggct gccgcaggcg cttcgctggt gcaggtaagc tccgcacact     60

ctcggccggt cccgagtccg actccctcaa gggtgacgcg agctctgccc tttaaccgga    120

aacgtctccc tgctcacccc acccccgcgc agacgcagtg ctgagcacac agctaccgga    180

caaagagtga cgcccggagc tggagttatg gcggctacgg agccgatctt ggcggccact    240

gggagtcccg cggcggtgcc accggagaaa ctggaaggag ccggttcgag ctcagcccct    300

gagcgtaact gtgtgggctc ctcgctgcca gaggcctcac cgcctgcccc tgagccttcc    360

agtcccaacg ccgcggtccc tgaagccatc cctacgcccc gagctgcggc ctccgcggcc    420

ctggagctgc ctctcgggcc cgcacccgtg agcgtagcgc ctcaggccga agctgaagcg    480

cgctccacac caggccccgc cggctctaga cgcacggatg tgcgcatcac tggctgagcg    540

gtggagctgc gggcggccag ggccgggcgc tctgtgcgga ctggggccat gatcgggccc    600

gggggcctga gcctgggacc ccaccccgtg ttaatgaaaa atgagttttg gcagcgcc      658


<210>  10032
<211>  109
<212>  PRT
<213>  Homo sapiens

<400>  10032

Met Ala Ala Thr Glu Pro Ile Leu Ala Ala Thr Gly Ser Pro Ala Ala 
1               5                   10                  15


Val Pro Pro Glu Lys Leu Glu Gly Ala Gly Ser Ser Ser Ala Pro Glu 
            20                  25                  30


Arg Asn Cys Val Gly Ser Ser Leu Pro Glu Ala Ser Pro Pro Ala Pro 
        35                  40                  45


Glu Pro Ser Ser Pro Asn Ala Ala Val Pro Glu Ala Ile Pro Thr Pro 
    50                  55                  60


Arg Ala Ala Ala Ser Ala Ala Leu Glu Leu Pro Leu Gly Pro Ala Pro 
65                  70                  75                  80


Val Ser Val Ala Pro Gln Ala Glu Ala Glu Ala Arg Ser Thr Pro Gly 
                85                  90                  95


Pro Ala Gly Ser Arg Arg Thr Asp Val Arg Ile Thr Gly 
            100                 105


<210>  10033
<211>  596
<212>  DNA
<213>  Homo sapiens

<400>  10033
agagactttc gcttccggct gccgcaggcg cttcgctggt gcaggtaagc tccgcacact     60

ctcggccggt cccgagtccg actccctcaa gggtgacgcg agctctgccc tttaaccgga    120

aacgtctccc tgctcacccc acccccgcgc agacgcagtg ctgagcacac agctaccgga    180

caaagagtga cgcccggagc tggagttatg gcggctacgg agccgatctt ggcggccact    240

gggagtcccg cggcggtgcc accggagaaa ctggaaggag ccggttcgag ctcagcccct    300

gagcgtaact gtgtgggctc ctcgctgcca gaggcctcac cgcctgcccc tgagccttcc    360

agtcccaacg ccgcggtccc tgaagccatc cctacgcccc gagctgcggc ctccgcggcc    420

ctggagctgc ctctcgggcc cgcacccgtg agcgtagcgc ctcaggccga agctgaagcg    480

cgctccacac caggccccgg ccgggcgctc tgtgcggact ggggccatga tcgggcccgg    540

gggcctgagc ctgggacccc accccgtgtt aatgaaaaat gagttttggc agcgcc        596


<210>  10034
<211>  124
<212>  PRT
<213>  Homo sapiens

<400>  10034

Met Ala Ala Thr Glu Pro Ile Leu Ala Ala Thr Gly Ser Pro Ala Ala 
1               5                   10                  15


Val Pro Pro Glu Lys Leu Glu Gly Ala Gly Ser Ser Ser Ala Pro Glu 
            20                  25                  30


Arg Asn Cys Val Gly Ser Ser Leu Pro Glu Ala Ser Pro Pro Ala Pro 
        35                  40                  45


Glu Pro Ser Ser Pro Asn Ala Ala Val Pro Glu Ala Ile Pro Thr Pro 
    50                  55                  60


Arg Ala Ala Ala Ser Ala Ala Leu Glu Leu Pro Leu Gly Pro Ala Pro 
65                  70                  75                  80


Val Ser Val Ala Pro Gln Ala Glu Ala Glu Ala Arg Ser Thr Pro Gly 
                85                  90                  95


Pro Gly Arg Ala Leu Cys Ala Asp Trp Gly His Asp Arg Ala Arg Gly 
            100                 105                 110


Pro Glu Pro Gly Thr Pro Pro Arg Val Asn Glu Lys 
        115                 120


<210>  10035
<211>  883
<212>  DNA
<213>  Homo sapiens

<400>  10035
ggacgcagag aagccagaga ctttcgcttc cggctgccgc aggcgcttcg ctggtgcagg     60

taagctccgc acactctcgg ccggtcccga gtccgactcc ctcaagggtg acgcgagctc    120

tgccctttaa ccggaaacgt ctccctgctc accccacccc cgcgcagacg cagtgctgag    180

cacacagcta ccggacaaag agtgacgccc ggagctggag ttatggcggc tacggagccg    240

atcttggcgg ccactgggag tcccgcggcg gtgccaccgg agaaactgga aggagccggt    300

tcgagctcag cccctgagcg taactgtgtg ggctcctcgc tgccagaggc ctcaccgcct    360

gcccctgagc cttccagtcc caacgccgcg gtccctgaag ccatccctac gccccgagct    420

gcggcctccg cggccctgga gctgcctctc gggcccgcac ccgtgagcgt agcgcctcag    480

gccgaagctg aagcgcgctc cacaccaggc cccgccggct ctagactcgg tcccgagacg    540

ttccgccagc gtttccggca gttccgctac caggatgcgg cgggtccccg ggaggctttc    600

cggcagctgc gggagctgtc ccgccagtgg ctgcggcctg acatccgcac caaggagcag    660

atcgtggaga tgctggtgca agagcagctg ctcgccatcc tgcccgaggc ggctcgggcc    720

cggcggatcc gccgccgcac ggatgtgcgc atcactggct gagcggtgga gctgcgggcg    780

gccagggccg ggcgctctgt gcggactggg gccatgatcg ggcccggggg cctgagcctg    840

ggaccccacc ccgtgttaat gaaaaatgag ttttggcagc gcc                      883


<210>  10036
<211>  179
<212>  PRT
<213>  Homo sapiens

<400>  10036

Met Ala Ala Thr Glu Pro Ile Leu Ala Ala Thr Gly Ser Pro Ala Ala 
1               5                   10                  15


Val Pro Pro Glu Lys Leu Glu Gly Ala Gly Ser Ser Ser Ala Pro Glu 
            20                  25                  30


Arg Asn Cys Val Gly Ser Ser Leu Pro Glu Ala Ser Pro Pro Ala Pro 
        35                  40                  45


Glu Pro Ser Ser Pro Asn Ala Ala Val Pro Glu Ala Ile Pro Thr Pro 
    50                  55                  60


Arg Ala Ala Ala Ser Ala Ala Leu Glu Leu Pro Leu Gly Pro Ala Pro 
65                  70                  75                  80


Val Ser Val Ala Pro Gln Ala Glu Ala Glu Ala Arg Ser Thr Pro Gly 
                85                  90                  95


Pro Ala Gly Ser Arg Leu Gly Pro Glu Thr Phe Arg Gln Arg Phe Arg 
            100                 105                 110


Gln Phe Arg Tyr Gln Asp Ala Ala Gly Pro Arg Glu Ala Phe Arg Gln 
        115                 120                 125


Leu Arg Glu Leu Ser Arg Gln Trp Leu Arg Pro Asp Ile Arg Thr Lys 
    130                 135                 140


Glu Gln Ile Val Glu Met Leu Val Gln Glu Gln Leu Leu Ala Ile Leu 
145                 150                 155                 160


Pro Glu Ala Ala Arg Ala Arg Arg Ile Arg Arg Arg Thr Asp Val Arg 
                165                 170                 175


Ile Thr Gly 



<210>  10037
<211>  1927
<212>  DNA
<213>  Homo sapiens

<400>  10037
agctgatggt atggtaggag gagtggagtg gagctcttgc cttgttactg aggaaatcta     60

tttgtttcta gtattactgg atttttgggg aaaaatttgt agtcctcccc ttgaaaggca    120

aaggggctag ttgtgccatt tgcctgcaca ggaaccatga ggagacatat ggtaacttat    180

gcctggcagc tcctgaagaa ggaactggga ctgtaccagc tcgccatgga tatcatcata    240

atgatccgag tgtgtaaaat gttccgccaa ggcctcaggg gattccggga atatcaaatc    300

attgagactg ctcactggaa gcaccctatc ttctccttct gggataaaaa gatgcaaagc    360

cgagtcacat ttgataccat ggacttcatt gcagaggagg gtcactttcc tccaaaggcc    420

attcagatca tgcagaagaa gccttcctgg agaacagagg atgagatcca ggccgtctgt    480

aacatcttgc aggttctgga tagctatcgg aactacgcag agcccctgca gctgctcctg    540

gccaaagtca tgcgctttga acggtttggt cgcaggcgtg tgatcatcaa gaaggggcag    600

aagggcaaca gcttttattt catctacctg ggcacagttg caataaccaa ggacgaggat    660

ggcagcagtg ccttcctaga tccccacccg aaattgctgc acaagggtag ctgttttggg    720

gaaatggacg ttctgcatgc ttcagtgagg aggtccacca tcgtctgtat ggaagaaacg    780

gagttcctgg ttgttgaccg ggaggacttc tttgctaata agctggacca ggaagttcag    840

aaggatgctc agtatcggtt tgaatttttt aggaagatgg agctgtttgc atcatggtct    900

gatgagaagc tctggcagct ggtagccatg gcgaagatag agaggttctc gtatgggcag    960

ctgatctcaa aagattttgg agagtcaccc ttcatcatgt ttatcagcaa gggcagctgt   1020

gaagtcctgc ggctgttgga ccttggggcc tccccttcct accgtagatg gatctggcag   1080

cacctggagc tgatagatgg cagacctctg aagacccacc tgagtgaata ctctcctatg   1140

gaaagattta aggaattcca gatcaaatca tatcctctgc aagactttag ctccttgaaa   1200

cttccacatc tcaaaaaagc ctgggggcta caggggacaa gcttcagcag gaagatcaga   1260

acctcaggag acactctccc caagatgctg ggcccgaaga tccaatccag gcctgctcag   1320

tcgatcaaat gtgccatgat caatatcaag cctggtgagc tccccaagga ggctgcagtg   1380

ggggcctacg tgaaggtgca cactgtggag cagggagaaa ttttggcctt ccttccagag   1440

ggtgaatgcg acacacgacc cttgatcctg atgagcctgg gaaatgagtt gatacggata   1500

aggaaggaaa tattttatga actgattgac aatgatgacg agatgataaa aaagttgtta   1560

aagctcaata ttgcattccc cagtgatgaa gatatgtgcc agaagttcct ccagcagaac   1620

agctggaata tctttcggaa ggacctgttg cagctgctcg tggagccttg ccaaagtcaa   1680

ctgttcactc caaaccggcc caagaagaga gagatctaca accctaagtc tgtggtcctg   1740

gatttgtgca gcatcaacaa gacgactaaa cctcgttatc ctatttttat ggcaccccag   1800

aaatacctcc ccccattgag gattgtccaa gccatcaaag cacctcggta caaaatccga   1860

gaactcttgg cttagtgtaa gagcacaggg gtccttattt aggacaaata aaggatggtg   1920

gattggg                                                             1927


<210>  10038
<211>  572
<212>  PRT
<213>  Homo sapiens

<400>  10038

Met Arg Arg His Met Val Thr Tyr Ala Trp Gln Leu Leu Lys Lys Glu 
1               5                   10                  15


Leu Gly Leu Tyr Gln Leu Ala Met Asp Ile Ile Ile Met Ile Arg Val 
            20                  25                  30


Cys Lys Met Phe Arg Gln Gly Leu Arg Gly Phe Arg Glu Tyr Gln Ile 
        35                  40                  45


Ile Glu Thr Ala His Trp Lys His Pro Ile Phe Ser Phe Trp Asp Lys 
    50                  55                  60


Lys Met Gln Ser Arg Val Thr Phe Asp Thr Met Asp Phe Ile Ala Glu 
65                  70                  75                  80


Glu Gly His Phe Pro Pro Lys Ala Ile Gln Ile Met Gln Lys Lys Pro 
                85                  90                  95


Ser Trp Arg Thr Glu Asp Glu Ile Gln Ala Val Cys Asn Ile Leu Gln 
            100                 105                 110


Val Leu Asp Ser Tyr Arg Asn Tyr Ala Glu Pro Leu Gln Leu Leu Leu 
        115                 120                 125


Ala Lys Val Met Arg Phe Glu Arg Phe Gly Arg Arg Arg Val Ile Ile 
    130                 135                 140


Lys Lys Gly Gln Lys Gly Asn Ser Phe Tyr Phe Ile Tyr Leu Gly Thr 
145                 150                 155                 160


Val Ala Ile Thr Lys Asp Glu Asp Gly Ser Ser Ala Phe Leu Asp Pro 
                165                 170                 175


His Pro Lys Leu Leu His Lys Gly Ser Cys Phe Gly Glu Met Asp Val 
            180                 185                 190


Leu His Ala Ser Val Arg Arg Ser Thr Ile Val Cys Met Glu Glu Thr 
        195                 200                 205


Glu Phe Leu Val Val Asp Arg Glu Asp Phe Phe Ala Asn Lys Leu Asp 
    210                 215                 220


Gln Glu Val Gln Lys Asp Ala Gln Tyr Arg Phe Glu Phe Phe Arg Lys 
225                 230                 235                 240


Met Glu Leu Phe Ala Ser Trp Ser Asp Glu Lys Leu Trp Gln Leu Val 
                245                 250                 255


Ala Met Ala Lys Ile Glu Arg Phe Ser Tyr Gly Gln Leu Ile Ser Lys 
            260                 265                 270


Asp Phe Gly Glu Ser Pro Phe Ile Met Phe Ile Ser Lys Gly Ser Cys 
        275                 280                 285


Glu Val Leu Arg Leu Leu Asp Leu Gly Ala Ser Pro Ser Tyr Arg Arg 
    290                 295                 300


Trp Ile Trp Gln His Leu Glu Leu Ile Asp Gly Arg Pro Leu Lys Thr 
305                 310                 315                 320


His Leu Ser Glu Tyr Ser Pro Met Glu Arg Phe Lys Glu Phe Gln Ile 
                325                 330                 335


Lys Ser Tyr Pro Leu Gln Asp Phe Ser Ser Leu Lys Leu Pro His Leu 
            340                 345                 350


Lys Lys Ala Trp Gly Leu Gln Gly Thr Ser Phe Ser Arg Lys Ile Arg 
        355                 360                 365


Thr Ser Gly Asp Thr Leu Pro Lys Met Leu Gly Pro Lys Ile Gln Ser 
    370                 375                 380


Arg Pro Ala Gln Ser Ile Lys Cys Ala Met Ile Asn Ile Lys Pro Gly 
385                 390                 395                 400


Glu Leu Pro Lys Glu Ala Ala Val Gly Ala Tyr Val Lys Val His Thr 
                405                 410                 415


Val Glu Gln Gly Glu Ile Leu Ala Phe Leu Pro Glu Gly Glu Cys Asp 
            420                 425                 430


Thr Arg Pro Leu Ile Leu Met Ser Leu Gly Asn Glu Leu Ile Arg Ile 
        435                 440                 445


Arg Lys Glu Ile Phe Tyr Glu Leu Ile Asp Asn Asp Asp Glu Met Ile 
    450                 455                 460


Lys Lys Leu Leu Lys Leu Asn Ile Ala Phe Pro Ser Asp Glu Asp Met 
465                 470                 475                 480


Cys Gln Lys Phe Leu Gln Gln Asn Ser Trp Asn Ile Phe Arg Lys Asp 
                485                 490                 495


Leu Leu Gln Leu Leu Val Glu Pro Cys Gln Ser Gln Leu Phe Thr Pro 
            500                 505                 510


Asn Arg Pro Lys Lys Arg Glu Ile Tyr Asn Pro Lys Ser Val Val Leu 
        515                 520                 525


Asp Leu Cys Ser Ile Asn Lys Thr Thr Lys Pro Arg Tyr Pro Ile Phe 
    530                 535                 540


Met Ala Pro Gln Lys Tyr Leu Pro Pro Leu Arg Ile Val Gln Ala Ile 
545                 550                 555                 560


Lys Ala Pro Arg Tyr Lys Ile Arg Glu Leu Leu Ala 
                565                 570


<210>  10039
<211>  2531
<212>  DNA
<213>  Homo sapiens

<400>  10039
gatggtatgg taggaggagt ggagtggagc tcttgccttg ttactgagga aatctatttg     60

tttctagtat tactggattt ttggggaaaa atttgtagtc ctccccttga aaggcaaagg    120

ggctagttgt gccatttgcc tgcacaggaa ccatgaggag acatatggta acttatgcct    180

ggcagctcct gaagaaggaa ctgggactgt accagctcgc catggatatc atcataatga    240

tccgagtgtg taaaatgttc cgccaaggcc tcaggggatt ccgggaatat caaatcattg    300

agactgctca ctggaagcac cctatcttct ccttctggga tgtaagcagt tgggctcagc    360

aggattatga gggctcaaag aagcccaata aattgcatcc cacttcctgg cctaagctca    420

gaactgagaa agaagacaaa aggaaaagca gatgagagac ccaatggtca cttttattaa    480

tggccatact tctgttggag agggtgactt acatcatcaa ccaagaggtt tacctaatac    540

tgaaccccag atttagacag ccttacatgc ctagccacag gcaacgctgg accaaggcag    600

gctccactgc aacagcaggc ctgctgccaa aactcatggc agggaaaggt ggagcaaaat    660

atgggctgag agggaaggag acaatcatgc ctagtttttc tctttccaaa ttcatcaaag    720

agtttaagtc actcctcaat gtaaaaggag agaggccagt agtgttctac taatacacct    780

ccctccatgt ggaaagaaac cttgggagta gagaggtggt ctccatttca atggtgatca    840

aaagagccag aagcaatcca ggaatcacaa taaccagggt tttctaaatg cccacacgct    900

ctctctattc gcgtctctac tttctttcct acacccctac ttcggtgcag gggcattttc    960

agggctttgt tcactgcggt gaccatgttt cttttatttt tttgagacgg agtcttgctc   1020

tgttgcccag gctggagtgc agtggcgcgt cttggctcac tgcaagctcc acctcccggg   1080

ttcacaccat tctcctgcct cagcctccct agtagctggg actacaggca cccgccacca   1140

cacccagcta attttttgta tttttagtag agacggggtt tcaccttgtt agccaggatg   1200

gtcttgatct cttgacctcg tgatccacct gcctcggcct cccaaagtgc tgggattaca   1260

ggcgtgagcc accgtgcctg gcctggtgac caggtttcta gatttcctag aaggtcccaa   1320

tttaaaatat tttatcccag tggtagatca tgtgcccttc tttagctcag aaaagttggt   1380

cacccttctg ctaacttgtt ctagttcccc agaggtatct tcattgctac tgggtgtgtt   1440

gctcagggct tcaaagtttc cccagcaatc acctggacaa atcctgccca tttttctgtt   1500

gtttcaggaa tgactagagc cagtccccac tcctctgcat ctagtgattc actccaagaa   1560

atttccctaa agggcttctg acagatagtg gccaaagaaa gggggatacg gggctggtga   1620

tgggggaagg aaaggcagcc ttaaactggt ttctgagggg ccagcaggta atataactag   1680

tgtgtatgta gctgagttta agatacagca ggccagctgg agaggaaaga tacacctcat   1740

ctaaagacat tcagatacaa atattatatt ttaagaccct gtgctggcca aaccaaacaa   1800

ggctgcagcc ctgtggttgg gctgagatga aaaacgaatg gagtagaaga actgtaacca   1860

aaagactcag gttagctctc aggaaggacc tcctgactct cagggtggca tgtaatggtg   1920

atgcaatggg ccctggagat cagagggctt tggttaccag aagacgtggc ctgatgcatg   1980

gggcagttgg aagctaagat gcagagtcac ttgttgtcag gggaatgtga ggctaagcct   2040

aaccacattg gccagccaga gtggcttgag cagagcagaa gcctctcaag ggcagcctat   2100

aagggtcata gggttgtcag gcggagcact gggcggctgg agtgcaggat caggtgggga   2160

gccctagact gcttcagtag atgtgtgaat ctggatgttt ctgagcactg cctctttcct   2220

tcagtagtct ccctgagaag caccacatgg ctatgcaaag gataaacacg ttgtgggggc   2280

gagacgggtc tgagtctaag gaacaaatga catgtggctt gaggccacac tccagacacg   2340

gaattgggtt tgctgaaagc cttgagttgg ggtctcagct agaccactga cttgctgtgt   2400

gatccttggg caagttcctt caccatctca gtcctacatg gagcttaata aaacctgctt   2460

tgtcctgatg actaaatgga gtaaggcagg gaggatacac tgtgcttggc tcattaaaga   2520

catttaacaa a                                                        2531


<210>  10040
<211>  100
<212>  PRT
<213>  Homo sapiens

<400>  10040

Met Arg Arg His Met Val Thr Tyr Ala Trp Gln Leu Leu Lys Lys Glu 
1               5                   10                  15


Leu Gly Leu Tyr Gln Leu Ala Met Asp Ile Ile Ile Met Ile Arg Val 
            20                  25                  30


Cys Lys Met Phe Arg Gln Gly Leu Arg Gly Phe Arg Glu Tyr Gln Ile 
        35                  40                  45


Ile Glu Thr Ala His Trp Lys His Pro Ile Phe Ser Phe Trp Asp Val 
    50                  55                  60


Ser Ser Trp Ala Gln Gln Asp Tyr Glu Gly Ser Lys Lys Pro Asn Lys 
65                  70                  75                  80


Leu His Pro Thr Ser Trp Pro Lys Leu Arg Thr Glu Lys Glu Asp Lys 
                85                  90                  95


Arg Lys Ser Arg 
            100


<210>  10041
<211>  465
<212>  DNA
<213>  Homo sapiens

<400>  10041
atccaggcct gctcagtcga tcaaatgtgc catgatcaat atcaagcctg gtgagctccc     60

caaggaggct gcagtggggg cctacgtgaa ggtgcacact gtggagcagg gagaaatttt    120

gtgatgaaga tatgtgccag aagttcctcc agcagaacag ctggaatatc tttcggaagg    180

acctgttgca gctgctcgtg gagccttgcc aaagtcaact gttcactcca aaccggccca    240

agaagagaga gatctacaac cctaagtctg tggtcctgga tttgtgcagc atcaacaaga    300

cgactaaacc tcgttatcct atttttatgg caccccagaa atacctcccc ccattgagga    360

ttgtccaagc catcaaagca cctcggtaca aaatccgaga actcttggct tagtgtaaga    420

gcacaggggt ccttatttag gacaaataaa ggatggtgga ttggg                    465


<210>  10042
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  10042

Met Ile Asn Ile Lys Pro Gly Glu Leu Pro Lys Glu Ala Ala Val Gly 
1               5                   10                  15


Ala Tyr Val Lys Val His Thr Val Glu Gln Gly Glu Ile Leu 
            20                  25                  30


<210>  10043
<211>  601
<212>  DNA
<213>  Homo sapiens

<400>  10043
aaaaaaaata aaagaaaaaa aagaatgaaa atctgcgggc agacctggcc agtctctgag     60

gtctaacttt ctgtgacttc tcccgagggt cttcaccagg ccttccttcc agagggtgaa    120

tgcgacacac gacccttgat cctgatgagc ctgggaaatg agttgatacg gataaggaag    180

gaaatatttt atgaactgat tgacaatgat gacgagatga taaaaaagtt gttaaagctc    240

aatattgcat tccccagtga tgaagatatg tgccagaagt tcctccagca gaacagctgg    300

aatatctttc ggaaggacct gttgcagctg ctcgtggagc cttgccaaag tcaactgttc    360

actccaaacc ggcccaagaa gagagagatc tacaacccta agtctgtggt cctggatttg    420

tgcagcatca acaagacgac taaacctcgt tatcctattt ttatggcacc ccagaaatac    480

ctccccccat tgaggattgt ccaagccatc aaagcacctc ggtacaaaat ccgagaactc    540

ttggcttagt gtaagagcac aggggtcctt atttaggaca aataaaggat ggtggattgg    600

g                                                                    601


<210>  10044
<211>  134
<212>  PRT
<213>  Homo sapiens

<400>  10044

Met Ser Leu Gly Asn Glu Leu Ile Arg Ile Arg Lys Glu Ile Phe Tyr 
1               5                   10                  15


Glu Leu Ile Asp Asn Asp Asp Glu Met Ile Lys Lys Leu Leu Lys Leu 
            20                  25                  30


Asn Ile Ala Phe Pro Ser Asp Glu Asp Met Cys Gln Lys Phe Leu Gln 
        35                  40                  45


Gln Asn Ser Trp Asn Ile Phe Arg Lys Asp Leu Leu Gln Leu Leu Val 
    50                  55                  60


Glu Pro Cys Gln Ser Gln Leu Phe Thr Pro Asn Arg Pro Lys Lys Arg 
65                  70                  75                  80


Glu Ile Tyr Asn Pro Lys Ser Val Val Leu Asp Leu Cys Ser Ile Asn 
                85                  90                  95


Lys Thr Thr Lys Pro Arg Tyr Pro Ile Phe Met Ala Pro Gln Lys Tyr 
            100                 105                 110


Leu Pro Pro Leu Arg Ile Val Gln Ala Ile Lys Ala Pro Arg Tyr Lys 
        115                 120                 125


Ile Arg Glu Leu Leu Ala 
    130


<210>  10045
<211>  5083
<212>  DNA
<213>  Homo sapiens

<400>  10045
ctctcttgcc agcgcagaga actgccaagt cagttccggt ccggcagaga tcgcggagag     60

acgcagaacg cagcccgctc ctccagggcc ctccaggccc tccggccccg ggccggcggg    120

tgaactgggg ggccccggga caggccgagc cctctgccct gcagataacg gaggcctctg    180

ctgtggctgc ccactggctg tgcccgccca ctggctgtgc ccagaccttg aagccgcagc    240

gaacctctct ttcccacccc acctcggtga ctaatggcgg ccgtggcgtc tcccagcccg    300

gaccccgccg gcacccgggt ctcccgaccc aagcctcgac gaaacccccg cagagccgcc    360

gggacgcagc gcctttgggc ggcgctgggc gtggtgggcc gggaagtatg gcggcagctc    420

gaacgccgcg cggcggaggc cattaaggcg tggacggccc gggaaggcgg cctagggacg    480

caagcaggct cggccgcctc tttaggccac ggagccgcgc agatccggtt cccgggtgac    540

cactctgtcg ccattgggcg agacctacct agtcctgacg acaacggaca aaggccttaa    600

ggggcctgga aggtgagcga agtcccgaac gacgacgggt ggaacggtta gcggccatcg    660

ggcggttggt cttcattcta ccagactttg ctgtcggaag agagaaatgg tagaatgaca    720

ggccacgttt ggcccgttgg aaatgcccac caccctctgg gaagatttac tggccgttta    780

tggaaggcct gtgtatataa tatgaaaaag ctgctctcaa ctccacccca accttttaat    840

agaaaacatt tgtcacatct agcccttcta gatggaaaga ggttgccgac gtatgataaa    900

atagagttag aaagttacac atcttgtaaa ttctcatttg tttaaaagaa atcatagaaa    960

atacatgtct tctggagatg acttttggaa atggagttgt taagacggcc tctggaagcg   1020

atacgtccac gtttgttaag tgggttagat gacatggagc tggaagacct gagaaggaag   1080

agaagaaggt tctatgctag actggtcata tttagaagac attttcatat tctatccatt   1140

gttttgtgtg cattttattc ctcactactg tgtatatagt tgacaatgct aagctttttt   1200

gaaatgtctc ttctttttag atgttctgaa gtgcctgata tgttaaaatt agaggtagca   1260

aaatcacatt ttgtaaatac ctttttgtta caattcatag gaaatatttt tgggggggaa   1320

tggccaaatc acctgttgag taatactcat tgtgtttgtg cagtggttca ggggaggaga   1380

gaggaggggg aggtgcagag agctctatgc catcctgttt acagcgaggc aagatgaatc   1440

attatgtctg tgcattttgt tttacttatc tgtgtatata gtgtacataa aggacagacg   1500

agtcctaatt gacaacatct agtctttctg gatgttaaag aggttgccag tgtatgacaa   1560

aagtagagtt agtaaactaa tatattttgt acattttgtt ttacaagtcc taggaaagat   1620

tgtcttctga aaatttgatg tcttctgggt tgatggagat gggaagggtt ctaggccaga   1680

atgttcacat ttggaagact ctttcaaatt ataactgttg ttacatgttt gcagtttatt   1740

caagactgct gtatacatag tagacaaatt aactccttac ttgaaacatc tagtctatct   1800

agatgtttag aagtgcccga tgtatgttaa atgtataggt agtaaaatac cactttgtaa   1860

atatcttttt gctaaaattc ataggaaatg cttttggaaa ttgaattgtg aagccacctt   1920

tgtgaacagt atagtaatgt ctatacttgt tcaatagttt agaggaggta ggagggaaga   1980

aattgcaaaa ggtaatatta ctagtgtgtt catacttgga cattttcaga caccattttt   2040

ctatatgttt tgtgcatttt gttttgctct gtatatagta tatataatgg acaaatagtc   2100

ctaatttttc aacatctagt ctctagatgt taaagaggtt gccagtgtat gacaaaggag   2160

taaaattagc atattttgta cactttgtgt tgaaattcgt aggaaaactt gtcttctgta   2220

aagacttttg cataggaatt tgtttgacca tctctaagca ttacacgtgc ctgtacttgt   2280

ccactggatt gaaggcagag aaggaaggga ggagggaatg attcaaggcc aaaatggcca   2340

catttagaag atacctcaga tgataaccat tgttatgtgt gtgcaatttt atttaacagt   2400

gctgtgtatg tggtggacaa gttatatgaa atatctagtc tttctagata tttggaagtg   2460

cttgatgtat ttaaaagtgg tagtagaata acactttgta aatagctttt aaaaactgat   2520

gggaaatgct gtttggaagt ggaattgttg aaccacctgg gaggtgggag ggaagaaatt   2580

gcaaatggtg ttttgccatt gtttattaga aaatttcagc ttaatccatt gtgtatatgt   2640

tacatgcatt tcatttaact ttgctatact gtatatattg tatatataac ggacaaatta   2700

gtcccgattt tataatatct agtctctaga tattaaagag gttgccaatg tatgacagaa   2760

gtagagttag taaactaaca cattttgtac actttgttaa aatttgtaga aaggctgtct   2820

tctgaaaagg acttttggaa gtgagataac atcagctcta agtgacacgt gcctatatcc   2880

atcaggttgg tggtggagag gagttggaag gaatgaaggg ttctagacca gaatgttcgt   2940

atttagaaga cactatcaga tataaccatt gttacatgtg tgtagtttat tcaaccctac   3000

tgtgtatata gcggacaaac ttaagtcctt atttgaaaca tctagtcttt ctagatgttt   3060

agaagtgcac aaagtatgtt aaaagtagag gtagtaaata acacattttg tagctatcct   3120

tttgatatga aatattgtct tggaaattga tcaattctct gagcagtacc cattttgata   3180

tttgtgctgg ttcaggggga aggaggagca caaagtgcaa agggctttct accagtgtcc   3240

agtgtgttta tgaggaggca cattgaccat tgtcccttat gtctgcattt tcatttactg   3300

tgctgtgtat atagtgtata taagcggaca taggagtcct aatttacgtc tagtcgatgt   3360

taaaaaggtt gccagtatat gacaaaagta gaattagtaa actactacat tgagtacact   3420

ttgtgttaaa attcataggg aagacttctt aaaaacaagt gaaattgtta aaaccccccc   3480

taagcattac agatggctta tagctgtcca cggggttggt agaggtggga aagggaaggg   3540

ttctaggcca gaatgttcct atttagaaga cactcaaatt acagtctgtg ttatgtatgt   3600

ataccattta ttcaatgcta ctgtgtatat aatggaaaac ttaagtccag tttgaaacat   3660

ctagtctttc taggtgttta aaagtgtaca acgtgcacaa tgtaggttaa cagtagaggg   3720

cttaagtaac acccctctaa gcatttgttt tcagtacttc ctaggagtgg ttgcatttgg   3780

gaatggaatt gttaaaactt gatgcttagg agcgaatgca gactattcat tgggtgtttg   3840

gggtggggga agggggggtg ggcagaggag gtatgcaggg agaggggttc tgtgctcctg   3900

agattagttc agatggtcta accattgttc tatatgtgca ttttagttaa tattgtgtat   3960

taaaggataa gtcttaatgc tcaaagtatg ttaaaaatag atgtagtaaa tcagtccctt   4020

tgtgaatgtc cttttgttag tttttaggaa ggcctgtcct ctgggagtga cctttattag   4080

tccacccctt ggagctagac atcctgtact tagtcacggg gatggtggaa gagggagaag   4140

aggaagggtg aagggaaggg ctctttgcta gtatctccat atctagacga tggttttaga   4200

tgataaccac aggtctacaa gagcgttttt agtaaagtgc ctgtgttcat tgtggacaaa   4260

gttattattt tgcaacatct aagctttacg aatggggtga caacttatga taaaaactag   4320

agctagtgaa ttagcctatt tgtaaatacc tttgttataa ttgataggat acatcttgga   4380

catggaattg ttaagccacc tctgagcagt gtatgtcagg acttgttcat taggttggca   4440

gcagaggggc agaaggaatt atacaggtag agatgtatgc agatgtgtcc atatatgtcc   4500

atatttacat tttgatagcc attgatgtat gcatctcttg gctgtactat aagaacacat   4560

taattcaatg gaaatacact ttgctaatat tttaatggta tagatctgct aatgaattct   4620

cttaaaaaca tactgtattc tgttgctgtg tgtttcattt taaattgagc attaagggaa   4680

tgcagcattt aaatcagaac tctgccaatg cttttatcta gaggcgtgtt gccatttttg   4740

tcttatatga aatttctgtc ccaagaaagg caggattaca tctttttttt tttttttagc   4800

agtttgagtt ggtgtagtgt attcttggtt atcagaatac tcatatagct ttgggatttt   4860

gaattggtaa atattcatga tgtgtgaaaa atcatgatac atactgtaca gtctcagtcc   4920

cataaaattg gatgttgtgc ctacacacag gatctagaag aatatgtcaa actataaact   4980

gcttgtgatt gtgaatgact ttgttctttg cttgtgtttt tcaatttcct ataatgcaca   5040

tactaacttt taaaaaataa aggttatttt aaaagcctgt att                     5083


<210>  10046
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  10046

Met Ala Ala Val Ala Ser Pro Ser Pro Asp Pro Ala Gly Thr Arg Val 
1               5                   10                  15


Ser Arg Pro Lys Pro Arg Arg Asn Pro Arg Arg Ala Ala Gly Thr Gln 
            20                  25                  30


Arg Leu Trp Ala Ala Leu Gly Val Val Gly Arg Glu Val Trp Arg Gln 
        35                  40                  45


Leu Glu Arg Arg Ala Ala Glu Ala Ile Lys Ala Trp Thr Ala Arg Glu 
    50                  55                  60


Gly Gly Leu Gly Thr Gln Ala Gly Ser Ala Ala Ser Leu Gly His Gly 
65                  70                  75                  80


Ala Ala Gln Ile Arg Phe Pro Gly Asp His Ser Val Ala Ile Gly Arg 
                85                  90                  95


Asp Leu Pro Ser Pro Asp Asp Asn Gly Gln Arg Pro 
            100                 105


<210>  10047
<211>  5339
<212>  DNA
<213>  Homo sapiens

<400>  10047
agttccggtc cggcagagat cgcggagaga cgcagaacgc agcccgctcc tccagggccc     60

tccaggccct ccggccccgg gccggcgggt gaactggggg gccccgggac aggccgagcc    120

ctctgccctg cagataacgg aggcctctgc tgtggctgcc cactggctgt gcccgcccac    180

tggctgtgcc cagaccttga agccgcagcg aacctctctt tcccacccca cctcggtgac    240

taatggcggc cgtggcgtct cccagcccgg accccgccgg cacccgggtc tcccgaccca    300

agcctcgacg aaacccccgc agagccgccg ggacgcagcg cctttgggcg gcgctgggcg    360

tggtgggccg ggaagtatgg cggcagctcg aacgccgcgc ggcggaggcc attaaggcgt    420

ggacggcccg ggaaggcggc ctagggacgc aagcaggctc ggccgcctct ttaggccacg    480

gagccgcgca gatccggttc ccgggtgacc actctgtcgc cattgggcga gacctaccta    540

gtcctgacga caacggacaa aggccttaag gggcctggaa ggtgagcgaa gtcccgaacg    600

acgacgggtg gaacggttag cggccatcgg gcggttggtc ttcattctac cagactttgc    660

tgtcggaaga gagaaatggt agaatgacag gccacgtttg gcccgttgga aatgcccacc    720

accctctggg aagatttact ggccgtttat ggaaggcctg tgtatataat atgaaaaagc    780

tgctctcaac tccaccccaa ccttttaata gaaaacattt gtcacatcta gcccttctag    840

atggaaagag gttgccgacg tatgataaaa tagagttaga aagttacaca tcttgtaaat    900

tctcatttgt ttaaaagaaa tcatagaaaa tacatgtctt ctggagatga cttttggaaa    960

tggagttgtt aagacggcct ctggaagcga tacgtccacg tttgttaagt gggttagatg   1020

acatggagct ggaagacctg agaaggaaga gaagaaggtt ctatgctaga ctggtcatat   1080

ttagaagaca ttttcatatt ctatccattg ttttgtgtgc attttattcc tcactactgt   1140

gtatatagtt gacaatgcta agcttttttg aaatgtctct tctttttaga tgttctgaag   1200

tgcctgatat gttaaaatta gaggtagcaa aatcacattt tgtaaatacc tttttgttac   1260

aattcatagg aaatattttt gggggggaat ggccaaatca cctgttgagt aatactcatt   1320

gtgtttgtgc agtggttcag gggaggagag aggaggggga ggtgcagaga gctctatgcc   1380

atcctgttta cagcgaggca agatgaatca ttatgtctgt gcattttgtt ttacttatct   1440

gtgtatatag tgtacataaa ggacagacga gtcctaattg acaacatcta gtctttctgg   1500

atgttaaaga ggttgccagt gtatgacaaa agtagagtta gtaaactaat atattttgta   1560

cattttgttt tacaagtcct aggaaagatt gtcttctgaa aatttgatgt cttctgggtt   1620

gatggagatg ggaagggttc taggccagaa tgttcacatt tggaagactc tttcaaatta   1680

taactgttgt tacatgtttg cagtttattc aagactgctg tatacatagt agacaaatta   1740

actccttact tgaaacatct agtctatcta gatgtttaga agtgcccgat gtatgttaaa   1800

tgtataggta gtaaaatacc actttgtaaa tatctttttg ctaaaattca taggaaatgc   1860

ttttggaaat tgaattgtga agccaccttt gtgaacagta tagtaatgtc tatacttgtt   1920

caatagttta gaggaggtag gagggaagaa attgcaaaag gtaatattac tagtgtgttc   1980

atacttggac attttcagac accatttttc tatatgtttt gtgcattttg ttttgctctg   2040

tatatagtat atataatgga caaatagtcc taatttttca acatctagtc tctagatgtt   2100

aaagaggttg ccagtgtatg acaaaggagt aaaattagca tattttgtac actttgtgtt   2160

gaaattcgta ggaaaacttg tcttctgtaa agacttttgc ataggaattt gtttgaccat   2220

ctctaagcat tacacgtgcc tgtacttgtc cactggattg aaggcagaga aggaagggag   2280

gagggaatga ttcaaggcca aaatggccac atttagaaga tacctcagat gataaccatt   2340

gttatgtgtg tgcaatttta tttaacagtg ctgtgtatgt ggtggacaag ttatatgaaa   2400

tatctagtct ttctagatat ttggaagtgc ttgatgtatt taaaagtggt agtagaataa   2460

cactttgtaa atagctttta aaaactgatg ggaaatgctg tttggaagtg gaattgttga   2520

accacctggg aggtgggagg gaagaaattg caaatggtgt tttgccattg tttattagaa   2580

aatttcagct taatccattg tgtatatgtt acatgcattt catttaactt tgctatactg   2640

tatatattgt atatataacg gacaaattag tcccgatttt ataatatcta gtctctagat   2700

attaaagagg ttgccaatgt atgacagaag tagagttagt aaactaacac attttgtaca   2760

ctttgttaaa atttgtagaa aggctgtctt ctgaaaagga cttttggaag tgagataaca   2820

tcagctctaa gtgacacgtg cctatatcca tcaggttggt ggtggagagg agttggaagg   2880

aatgaagggt tctagaccag aatgttcgta tttagaagac actatcagat ataaccattg   2940

ttacatgtgt gtagtttatt caaccctact gtgtatatag cggacaaact taagtcctta   3000

tttgaaacat ctagtctttc tagatgttta gaagtgcaca aagtatgtta aaagtagagg   3060

tagtaaataa cacattttgt agctatcctt ttgatatgaa atattgtctt ggaaattgat   3120

caattctctg agcagtaccc attttgatat ttgtgctggt tcagggggaa ggaggagcac   3180

aaagtgcaaa gggctttcta ccagtgtcca gtgtgtttat gaggaggcac attgaccatt   3240

gtcccttatg tctgcatttt catttactgt gctgtgtata tagtgtatat aagcggacat   3300

aggagtccta atttacgtct agtcgatgtt aaaaaggttg ccagtatatg acaaaagtag   3360

aattagtaaa ctactacatt gagtacactt tgtgttaaaa ttcataggga agacttctta   3420

aaaacaagtg aaattgttaa aaccccccct aagcattaca gatggcttat agctgtccac   3480

ggggttggta gaggtgggaa agggaagggt tctaggccag aatgttccta tttagaagac   3540

actcaaatta cagtctgtgt tatgtatgta taccatttat tcaatgctac tgtgtatata   3600

atggaaaact taagtccagt ttgaaacatc tagtctttct aggtgtttaa aagtgtacaa   3660

cggcctgtcg cagtggcgca tgcctgtaat cccagcactt tgggaggccg aggcaggcgg   3720

atcacgaggt caagagatca ggaccatctt ggccaacatg gtgaaacccc atctttacta   3780

aaaatacaaa aattagctgg tcgtggtggt gcccacctgt agccccagtt actcgagagg   3840

ctgaggcagg agaatcgctt gaacttggga ggcggaagtt gcagtgagcc aagatcgcac   3900

cactgcactc cagcctggcg acagagcgag gctccgtttc aaaaaaaaaa gtgcacaatg   3960

taggttaaca gtagagggct taagtaacac ccctctaagc atttgttttc agtacttcct   4020

aggagtggtt gcatttggga atggaattgt taaaacttga tgcttaggag cgaatgcaga   4080

ctattcattg ggtgtttggg gtgggggaag ggggggtggg cagaggaggt atgcagggag   4140

aggggttctg tgctcctgag attagttcag atggtctaac cattgttcta tatgtgcatt   4200

ttagttaata ttgtgtatta aaggataagt cttaatgctc aaagtatgtt aaaaatagat   4260

gtagtaaatc agtccctttg tgaatgtcct tttgttagtt tttaggaagg cctgtcctct   4320

gggagtgacc tttattagtc caccccttgg agctagacat cctgtactta gtcacgggga   4380

tggtggaaga gggagaagag gaagggtgaa gggaagggct ctttgctagt atctccatat   4440

ctagacgatg gttttagatg ataaccacag gtctacaaga gcgtttttag taaagtgcct   4500

gtgttcattg tggacaaagt tattattttg caacatctaa gctttacgaa tggggtgaca   4560

acttatgata aaaactagag ctagtgaatt agcctatttg taaatacctt tgttataatt   4620

gataggatac atcttggaca tggaattgtt aagccacctc tgagcagtgt atgtcaggac   4680

ttgttcatta ggttggcagc agaggggcag aaggaattat acaggtagag atgtatgcag   4740

atgtgtccat atatgtccat atttacattt tgatagccat tgatgtatgc atctcttggc   4800

tgtactataa gaacacatta attcaatgga aatacacttt gctaatattt taatggtata   4860

gatctgctaa tgaattctct taaaaacata ctgtattctg ttgctgtgtg tttcatttta   4920

aattgagcat taagggaatg cagcatttaa atcagaactc tgccaatgct tttatctaga   4980

ggcgtgttgc catttttgtc ttatatgaaa tttctgtccc aagaaaggca ggattacatc   5040

tttttttttt tttttagcag tttgagttgg tgtagtgtat tcttggttat cagaatactc   5100

atatagcttt gggattttga attggtaaat attcatgatg tgtgaaaaat catgatacat   5160

actgtacagt ctcagtccca taaaattgga tgttgtgcct acacacagga tctagaagaa   5220

tatgtcaaac tataaactgc ttgtgattgt gaatgacttt gttctttgct tgtgtttttc   5280

aatttcctat aatgcacata ctaactttta aaaaataaag gttattttaa aagcctgta    5339


<210>  10048
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  10048

Met Ala Ala Val Ala Ser Pro Ser Pro Asp Pro Ala Gly Thr Arg Val 
1               5                   10                  15


Ser Arg Pro Lys Pro Arg Arg Asn Pro Arg Arg Ala Ala Gly Thr Gln 
            20                  25                  30


Arg Leu Trp Ala Ala Leu Gly Val Val Gly Arg Glu Val Trp Arg Gln 
        35                  40                  45


Leu Glu Arg Arg Ala Ala Glu Ala Ile Lys Ala Trp Thr Ala Arg Glu 
    50                  55                  60


Gly Gly Leu Gly Thr Gln Ala Gly Ser Ala Ala Ser Leu Gly His Gly 
65                  70                  75                  80


Ala Ala Gln Ile Arg Phe Pro Gly Asp His Ser Val Ala Ile Gly Arg 
                85                  90                  95


Asp Leu Pro Ser Pro Asp Asp Asn Gly Gln Arg Pro 
            100                 105


<210>  10049
<211>  1233
<212>  DNA
<213>  Homo sapiens

<400>  10049
gtggttgcat ttgggaatgg aattgttaaa acttgatgct taggagcgaa tgcagactat     60

tcattgggtg tttggggtgg gggaaggggg ggtgggcaga ggaggtatgc agggagaggg    120

gttctgtgct cctgagatta gttcagatgg tctaaccatt gttctatatg tgcattttag    180

ttaatattgt gtattaaagg ataagtctta atgctcaaag tatgttaaaa atagatgtag    240

taaatcagtc cctttgtgaa tgtccttttg ttagttttta ggaaggcctg tcctctggga    300

gtgaccttta ttagtccacc ccttggagct agacatcctg tacttagtca cggggatggt    360

ggaagaggga gaagaggaag ggtgaaggga agggctcttt gctagtatct ccatatctag    420

acgatggttt tagatgataa ccacaggtct acaagagcgt ttttagtaaa gtgcctgtgt    480

tcattgtgga caaagttatt attttgcaac atctaagctt tacgaatggg gtgacaactt    540

atgataaaaa ctagagctag tgaattagcc tatttgtaaa tacctttgtt ataattgata    600

ggatacatct tggacatgga attgttaagc cacctctgag cagtgtatgt caggacttgt    660

tcattaggtt ggcagcagag gggcagaagg aattatacag gtagagatgt atgcagatgt    720

gtccatatat gtccatattt acattttgat agccattgat gtatgcatct cttggctgta    780

ctataagaac acattaattc aatggaaata cactttgcta atattttaat ggtatagatc    840

tgctaatgaa ttctcttaaa aacatactgt attctgttgc tgtgtgtttc attttaaatt    900

gagcattaag ggaatgcagc atttaaatca gaactctgcc aatgctttta tctagaggcg    960

tgttgccatt tttgtcttat atgaaatttc tgtcccaaga aaggcaggat tacatctttt   1020

tttttttttt tagcagtttg agttggtgta gtgtattctt ggttatcaga ataccataaa   1080

attggatgtt gtgcctacac acaggatcta gaagaatatg tcaaactata aactgcttgt   1140

gattgtgaat gactttgttc tttgcttgtg tttttcaatt tcctataatg cacatactaa   1200

cttttaaaaa ataaaggtta ttttaaaagc ctg                                1233


<210>  10050
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  10050

Met Leu Leu Ser Arg Gly Val Leu Pro Phe Leu Ser Tyr Met Lys Phe 
1               5                   10                  15


Leu Ser Gln Glu Arg Gln Asp Tyr Ile Phe Phe Phe Phe Phe Ser Ser 
            20                  25                  30


Leu Ser Trp Cys Ser Val Phe Leu Val Ile Arg Ile Pro 
        35                  40                  45


<210>  10051
<211>  468
<212>  DNA
<213>  Homo sapiens

<400>  10051
ctcctgctca aaagcaggat gccagctggg cgcaggggct cacacccggc caaaatgctt     60

aattttaaca agcacttact ttctgtctta tatgcagatg ttgtgttata ctctagggat    120

acaagttgga taagacatag tcccttgttg aatggatgga tgaataaaaa tgctcctctg    180

ggcctcaccc agaaatctgc ctgataccca ctctaaacaa aataaaacaa cttatcacag    240

gggatttgaa caaaggaaaa taaaaaatat aaagttcaaa atcattaacc tggcatccaa    300

gaccttctac aatctgattc taattttgtc tacctaccac actcttagct ctagccaaac    360

taaagtgttt tgttgtccta gaaaacacta tgtctccact tgcatgttcg tttgcccagg    420

ctctggtttt ctcccatggt ttcttttcct gtttttctct cccatttg                 468


<210>  10052
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  10052

Met Pro Ala Gly Arg Arg Gly Ser His Pro Ala Lys Met Leu Asn Phe 
1               5                   10                  15


Asn Lys His Leu Leu Ser Val Leu Tyr Ala Asp Val Val Leu Tyr Ser 
            20                  25                  30


Arg Asp Thr Ser Trp Ile Arg His Ser Pro Leu Leu Asn Gly Trp Met 
        35                  40                  45


Asn Lys Asn Ala Pro Leu Gly Leu Thr Gln Lys Ser Ala 
    50                  55                  60


<210>  10053
<211>  359
<212>  DNA
<213>  Homo sapiens

<400>  10053
agagtgggta tcaggcagat ttctgggtga ggcccagagg agcattttta ttcatccatc     60

cattcaacaa gggactatgt cttatccaac ttgtatccct agagtataac acaacatctg    120

catataagac agaaagtcag tggattcaaa acgatgaaag tggattcaaa acctctgtca    180

aggggtgctg tcctttcctg gccaagtctc ttttattctc ttagggctgc aacctcttca    240

cctgggaaat gaatggtcct gtgatttaca agagcagggt ccaggctgaa ggtgcaggcc    300

ctatccaaga cacaacattt ccagtggcag agataaaaaa gtaagatttc agactcaaa     359


<210>  10054
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  10054

Met Asn Gly Pro Val Ile Tyr Lys Ser Arg Val Gln Ala Glu Gly Ala 
1               5                   10                  15


Gly Pro Ile Gln Asp Thr Thr Phe Pro Val Ala Glu Ile Lys Lys 
            20                  25                  30


<210>  10055
<211>  616
<212>  DNA
<213>  Homo sapiens

<400>  10055
aaagtggcaa caacactgat cttgccctcc tccctaagtt gctacaaaaa gacatagtaa     60

aaatctttag ggtgccgggc agggtggctc acggctgtaa tctcagcact ttgggaggct    120

gaggcaggca gatcaccatg tttgccaggc tggtcttgaa ctcctgacct tgtgatccac    180

cctcctcggc ctcccaaagt gctgggatta caggcatgaa tcaccgtgcc cagccccagt    240

ctattctttt atctcctgga ccactgcagt ggtttcctac tggtcctgcc tgcctctgat    300

ccctccccac ccatttcttc tacacataca gtcacataat tgtctggaag cacagctttg    360

atcttgtctt tcccttccta atagaacttg cccatttttt caacttgaga ggtcaccagg    420

atcctagttc aatttcccaa tgaagactta atctttcctt gaatacatat attgacaagg    480

agttcatcac tcccaaggtg gtccattcca ttcttgggta gctccaactg ttagggagtt    540

ctttatagtg agctgaaatt gtcttcctgg atatcccccc actggaggtg atgtgatgga    600

attctctttt tttttt                                                    616


<210>  10056
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  10056

Lys Ser Leu Gly Cys Arg Ala Gly Trp Leu Thr Ala Val Ile Ser Ala 
1               5                   10                  15


Leu Trp Glu Ala Glu Ala Gly Arg Ser Pro Cys Leu Pro Gly Trp Ser 
            20                  25                  30


<210>  10057
<211>  3528
<212>  DNA
<213>  Homo sapiens

<400>  10057
cagaattgtt gggcttcatc ttggctctgt gctgcctgga ggggagacct aggataggct     60

cctgatctgc aaaatgggga taatcccagc tgccacttaa gtgagacaag tgcctgactg    120

acagaagttc ttgcccccgg ggagctggtg tggacagagg agggagccta gacatggagg    180

agaaggacta cagtgaggcc gatggccttt cggagaggac cacgcccagc aaggcccaga    240

aatcgcccca gaagattgcc aagaaataca agagtgccat ctgccgggtc actctgcttg    300

atgcctcgga gtatgagtgt gaggtggaga aacatggccg gggccaggtg ctgtttgacc    360

tggtctgtga acacctcaac ctcctagaga aggactactt cggcctgacc ttctgtgatg    420

ctgacagcca gaagaactgg ctggacccct ccaaggagat caagaagcag atccggagta    480

gcccctggaa ttttgccttc acagtcaagt tctacccgcc tgatcctgcc cagctgacag    540

aagacatcac aagatactac ctgtgcctgc agctgcgggc agacatcatc acgggccggc    600

tgccatgctc ctttgtcacg catgccctac tgggctccta cgctgtgcag gctgagctgg    660

gtgactatga tgctgaggag catgtgggca actatgtcag cgagctccgc ttcgccccta    720

accagacccg ggagctggag gagaggatca tggagctgca taagacatat agggggatga    780

ccccgggaga agcagaaatc cacttcttag agaatgccaa gaagctttcc atgtacggag    840

tagacctgca ccatgccaag gactctgagg gcatcgacat catgttaggc gtttgtgcca    900

atggcctgct catctaccgg gaccggctga gaatcaaccg ctttgcctgg cccaagatcc    960

tcaagatctc ctacaagagg agtaacttct atatcaagat ccggcctggg gagtatgagc   1020

aatttgagag cacaattggc tttaagctcc caaaccaccg gtcagccaag agactgtgga   1080

aggtctgcat cgagcatcat acattcttcc ggctggtgtc ccctgagccc ccacccaagg   1140

gcttcctggt gatgggctcc aagttccggt acagtgggag gacccaggca cagactcgcc   1200

aggccagcgc cctcattgac cggcctgcac ccttctttga gcgttcttcc agcaaacggt   1260

acaccatgtc ccgcagcctt gatggagcag agttctcccg cccagcctcg gtcagcgaga   1320

accatgatgc agggcctgac ggtgacaagc gggatgagga tggcgagtct ggggggcaac   1380

ggtcagaggc tgaggaggga gaggtcagga ctccaaccaa gatcaaggag ctaaagttct   1440

tagacaagcc agaagatgtc ttgctgaagc accaggccag catcaatgag ctcaaaagga   1500

ccctgaagga gcccaacagc aaactcatcc accgggatcg agactgggaa cgggagcgca   1560

ggctgccctc ctcccccgcc tccccctccc ccaagggcac ccctgagaaa gccaatgaga   1620

gagcagggct gagggagggc tccgaggaga aagtcaaacc accacgtccc cgggccccag   1680

agagtgacac aggcgatgag gaccaggacc aggagaggga cacggtgttc ctgaaggaca   1740

accacctggc cattgagcgc aagtgctcca gcatcacggt cagctctacg tctagcctgg   1800

aggctgaggt ggacttcacg gtcattggtg actaccatgg cagcgccttc gaagacttct   1860

cccgcagcct gcctgagctc gaccgggaca aaagcgactc ggacactgag ggcctgctgt   1920

tctcccggga tctcaacaag ggggccccca gccaggatga tgagtctggg ggcattgagg   1980

acagcccgga tcgaggggcc tgctccaccc cggatatgcc ccagtttgag cccgtgaaaa   2040

cagaaaccat gactgtcagc agtctggcca ttagaaagaa gattgagccg gaggccgtac   2100

tgcagaccag agtctccgct atggataaca cccaggagaa cagtctcaag tccgggaagg   2160

gggcagctgc catgatccca ggcccacaga cggtggccac ggaaatccgt tctctttctc   2220

cgatcatcgg gaaagatgtc ctcaccagca cctacggcgc cactgcggaa accctctcaa   2280

cctccaccac cacccatgtc accaaaactg tgaaaggagg gttttctgag acaaggatcg   2340

agaagcgaat catcattact ggggatgaag atgtcgatca agaccaggcc ctggctttgg   2400

ccatcaagga ggccaaactg cagcatcctg atatgctggt aaccaaagct gtcgtataca   2460

gagaaacaga cccatcccca gaggagaggg acaagaagcc acaggaatcc tgacctctgt   2520

gaagagatcc tggcatttct ggtccaaccc aagccagaga accattaaga aggggccttc   2580

attctggatt ctccgacgca acactgacgt cccagctgcg acgtactgtc actgatgaga   2640

gactgggaag ggaaaagcat atatatatag atatatagag atatagatat atatacagga   2700

aacaccgcat ccttgcactg ctgctggggc tggcagagca gttggctgac agcaacaacc   2760

gacatctgaa cacctacatt tcctttgcag acaaattgaa gaactggtgg gatttttttc   2820

aagaaaaaaa attatataat aactataatc ccttgctcac ccctttcccc cgccaaataa   2880

gaaacgcaag ccagaccacg atgattgtag aagtccctcc cgccctggtt ctgcacgtta   2940

cagttagcag acgagcaatt ccatttgttc ttctccagca tctctaaggc ccacttgaat   3000

gcaaaggaaa acacttgcac agcaaagcaa gagaagtcac agcagcaaga cacgcacagt   3060

caaccatttt ccgagaaaaa aagaaaattc cccacttgga aagaaagagg aggaacactg   3120

gattcttact ttctggatct tgacactggg ctgcaaaacc taccttcctc tctcccgcct   3180

cccctcaccc tcaactctca atgtcttgct gtcattttct gtctcggctc cctcctcccc   3240

cttccccctt cccccacccc acacccttca ccctctgtgt cctggtcctt ctgagggcca   3300

ctgcagatga ctctcctttg aaatgagaaa aagaaaagaa agcaagaaca gaaaacgaag   3360

ccacaggaag ggaagtagac attgtatgct tatggtttct cattatgaag gtgcagcttg   3420

taggaggttt gtacggatgt gctttgaagt tatgtatatt acatataaca ggaaaaaata   3480

ttaaaataaa cagtgctggt aagtatgaag ctgacattct aaaattat                3528


<210>  10058
<211>  779
<212>  PRT
<213>  Homo sapiens

<400>  10058

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val 
    50                  55                  60


Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe 
65                  70                  75                  80


Cys Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile 
                85                  90                  95


Lys Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys 
            100                 105                 110


Phe Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr 
        115                 120                 125


Tyr Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro 
    130                 135                 140


Cys Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala 
145                 150                 155                 160


Glu Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser 
                165                 170                 175


Glu Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile 
            180                 185                 190


Met Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu 
        195                 200                 205


Ile His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp 
    210                 215                 220


Leu His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val 
225                 230                 235                 240


Cys Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg 
                245                 250                 255


Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe 
            260                 265                 270


Tyr Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile 
        275                 280                 285


Gly Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val 
    290                 295                 300


Cys Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro 
305                 310                 315                 320


Pro Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
                325                 330                 335


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
            340                 345                 350


Pro Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser 
        355                 360                 365


Leu Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His 
    370                 375                 380


Asp Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly 
385                 390                 395                 400


Gly Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys 
                405                 410                 415


Ile Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys 
            420                 425                 430


His Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn 
        435                 440                 445


Ser Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu 
    450                 455                 460


Pro Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala 
465                 470                 475                 480


Asn Glu Arg Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro 
                485                 490                 495


Pro Arg Pro Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp 
            500                 505                 510


Gln Glu Arg Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu 
        515                 520                 525


Arg Lys Cys Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala 
    530                 535                 540


Glu Val Asp Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu 
545                 550                 555                 560


Asp Phe Ser Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser 
                565                 570                 575


Asp Thr Glu Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro 
            580                 585                 590


Ser Gln Asp Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly 
        595                 600                 605


Ala Cys Ser Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu 
    610                 615                 620


Thr Met Thr Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu 
625                 630                 635                 640


Ala Val Leu Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Glu Asn 
                645                 650                 655


Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro Gln 
            660                 665                 670


Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys Asp 
        675                 680                 685


Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr Ser 
    690                 695                 700


Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu Thr 
705                 710                 715                 720


Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp Gln 
                725                 730                 735


Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His Pro 
            740                 745                 750


Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro Ser 
        755                 760                 765


Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    770                 775


<210>  10059
<211>  5953
<212>  DNA
<213>  Homo sapiens

<400>  10059
cttggctctg tgctgcctgg aggggagacc taggataggc tcctgatctg caaaatgggg     60

ataatcccag ctgccactta agtgagacaa gtgcctgact gacagaagtt cttgcccccg    120

gggagctggt gtggacagag gagggagcct agacatggag gagaaggact acagtgaggc    180

cgatggcctt tcggagagga ccacgcccag caaggcccag aaatcgcccc agaagattgc    240

caagaaatac aagagtgcca tctgccgggt cactctgctt gatgcctcgg agtatgagtg    300

tgaggtggag aaacatggcc ggggccaggt gctgtttgac ctggtctgtg aacacctcaa    360

cctcctagag aaggactact tcggcctgac cttctgtgat gctgacagcc agaagaactg    420

gctggacccc tccaaggaga tcaagaagca gatccggagt agcccctgga attttgcctt    480

cacagtcaag ttctacccgc ctgatcctgc ccagctgaca gaagacatca caagatacta    540

cctgtgcctg cagctgcggg cagacatcat cacgggccgg ctgccatgct cctttgtcac    600

gcatgcccta ctgggctcct acgctgtgca ggctgagctg ggtgactatg atgctgagga    660

gcatgtgggc aactatgtca gcgagctccg cttcgcccct aaccagaccc gggagctgga    720

ggagaggatc atggagctgc ataagacata tagggggatg accccgggag aagcagaaat    780

ccacttctta gagaatgcca agaagctttc catgtacgga gtagacctgc accatgccaa    840

ggactctgag ggcatcgaca tcatgttagg cgtttgtgcc aatggcctgc tcatctaccg    900

ggaccggctg agaatcaacc gctttgcctg gcccaagatc ctcaagatct cctacaagag    960

gagtaacttc tatatcaaga tccggcctgg ggagtatgag caatttgaga gcacaattgg   1020

ctttaagctc ccaaaccacc ggtcagccaa gagactgtgg aaggtctgca tcgagcatca   1080

tacattcttc cggctggtgt cccctgagcc cccacccaag ggcttcctgg tgatgggctc   1140

caagttccgg tacagtggga ggacccaggc acagactcgc caggccagcg ccctcattga   1200

ccggcctgca cccttctttg agcgttcttc cagcaaacgg tacaccatgt cccgcagcct   1260

tgatggagca gagttctccc gcccagcctc ggtcagcgag aaccatgatg cagggcctga   1320

cggtgacaag cgggatgagg atggcgagtc tggggggcaa cggtcagagg ctgaggaggg   1380

agaggtcagg actccaacca agatcaagga gctaaagttc ttagacaagc cagaagatgt   1440

cttgctgaag caccaggcca gcatcaatga gctcaaaagg accctgaagg agcccaacag   1500

caaactcatc caccgggatc gagactggga acgggagcgc aggctgccct cctcccccgc   1560

ctccccctcc cccaagggca cccctgagaa agccaatgag agagcagggc tgagggaggg   1620

ctccgaggag aaagtcaaac caccacgtcc ccgggcccca gagagtgaca caggcgatga   1680

ggaccaggac caggagaggg acacggtgtt cctgaaggac aaccacctgg ccattgagcg   1740

caagtgctcc agcatcacgg tcagctctac gtctagcctg gaggctgagg tggacttcac   1800

ggtcattggt gactaccatg gcagcgcctt cgaagacttc tcccgcagcc tgcctgagct   1860

cgaccgggac aaaagcgact cggacactga gggcctgctg ttctcccggg atctcaacaa   1920

gggggccccc agccaggatg atgagtctgg gggcattgag gacagcccgg atcgaggggc   1980

ctgctccacc ccggatatgc cccagtttga gcccgtgaaa acagaaacca tgactgtcag   2040

cagtctggcc attagaaaga agattgagcc ggaggccgta ctgcagacca gagtctccgc   2100

tatggataac acccaggaga acagtctcaa gtccgggaag ggggcagctg ccatgatccc   2160

aggcccacag acggtggcca cggaaatccg ttctctttct ccgatcatcg ggaaagatgt   2220

cctcaccagc acctacggcg ccactgcgga aaccctctca acctccacca ccacccatgt   2280

caccaaaact gtgaaaggag ggttttctga gacaaggatc gagaagcgaa tcatcattac   2340

tggggatgaa gatgtcgatc aagaccaggc cctggctttg gccatcaagg aggccaaact   2400

gcagcatcct gatatgctgg taaccaaagc tgtcgtatac agagaaacag acccatcccc   2460

agaggagagg gacaagaagc cacaggaatc ctgacctctg tgaagagatc ctggcatttc   2520

tggtccaacc caagccagag aaccattaag aaggggcctt cattctggat tctccgacgc   2580

aacactgacg tcccagctgc gacgtactgt cactgatgag agactgggaa gggaaaagca   2640

tatatatata gatatataga gatatagata tatatacagg aaacaccgca tccttgcact   2700

gctgctgggg ctggcagagc agttggctga cagcaacaac cgacatctga acacctacat   2760

ttcctttgca gacaaattga agaactggtg ggattttttt caagaaaaaa aattatataa   2820

taactataat cccttgctca cccctttccc ccgccaaata agaaacgcaa gccagaccac   2880

gatgattgta gaagtccctc ccgccctggt tctgcacgtt acagttagca gacgagcaat   2940

tccatttgtt cttctccagc atctctaagg cccacttgaa tgcaaaggaa aacacttgca   3000

cagcaaagca agagaagtca cagcagcaag acacgcacag tcaaccattt tccgagaaaa   3060

aaagaaaatt ccccacttgg aaagaaagag gaggaacact ggattcttac tttctggatc   3120

ttgacactgg gctgcaaaac ctaccttcct ctctcccgcc tcccctcacc ctcaactctc   3180

aatgtcttgc tgtcattttc tgtctcggct ccctcctccc ccttccccct tcccccaccc   3240

cacacccttc accctctgtg tcctggtcct tctgagggcc actgcagatg actctccttt   3300

gaaatgagaa aaagaaaaga aagcaagaac agaaaacgaa gccacaggaa gggaagtaga   3360

cattgtatgc ttatggtttc tcattatgaa ggtgcagctt gtaggaggtt tgtacggatg   3420

tgctttgaag ttatgtatat tacatataac aggaaaaaat attaaaataa acagtgctgg   3480

taagtatgaa gctgacattc taaaattata attatctgac tgtgattgat gtatcctgag   3540

gttcctagat ctcactgaac tggcccagct aaggagacct ggactctggg tgtgggttgg   3600

ctcacagtag gggctgacgg gttcagtgta gtaatactgt gtgtggtgtt tgtaattggt   3660

tgattggtgg ggaggggtgg ggggccctaa tggagaggtg tgggtttggc aagaaagaag   3720

caacacagat gtcgtcccca aaatgccagt tcaagacacc ttctccctgc ccccctggta   3780

gtaacagtca gggcctggtc tgtgctcagg tactgggtcc cagtctggga ctctgctgct   3840

gaagttgcca cagtagaggt ccctggctta gtccttatct ccctacgggg cttgccttgg   3900

ttttcagtct tctctctctt tctctctttt tttttttttt gccacattct gcccttccct   3960

gaccccattg taataaccaa ctccatatcc aaagggaggt ggtgctctca gccattgtag   4020

aagatggtgg ctttaacctg actgtctaaa aattcccagc taagcctttt cctctactct   4080

cttccttgtt ctgaatcatt tcttcttctc aggccaaagt agccatggta aggaggcttc   4140

atggggcaga ccctgaaaga tcaaaactgc atttgcaaag ccctcccctg tcccaggaca   4200

aagctgagac tgacgggtga tgttgctcat aggctccagc tctgcataag accttggctt   4260

ggagacctcc ctctcagtca acagctgaac tctgagcttg tgcccagaaa ttaccccaag   4320

accacaggaa cccttcaaga agctcccatc acaagcttgg cattgctctc tgccacacgt   4380

gggcttcctc aggcttgtct gccacaagct acttctctga gctcagaaag tgccccttga   4440

tgagggaaaa tgtcccactg cactgcgaat ttctcagttc cattttacct cccagtcctc   4500

cttctaaacc agttaataaa ttcattccac aagtatttac tgattacctg cttgtgccag   4560

ggactattct caggctgaag aaggtgggag gggagggcgg aacctgagga gccacctgag   4620

ccagctttat atttcaacca tggctggccc atctgagagc atctccccac tctcgccaac   4680

ctatcggggc atagcccagg gatgccccca ggcggcccag gttagatgcg tccctttggc   4740

ttgtcagtga tgacatacac cttagctgct tagctggtgc tggcctgagg cagggcagga   4800

aatcagaata gcatttgctt ctctgggcaa atgggaagtt cagcggggca gcagaatcag   4860

tggcattccc cctggtgcag gccggtgggt ccactccaac tccccctgag tgtagcagca   4920

cactttccat acaccaggtt ctttctacaa tcctggtgga aaagccacag aaccttcttc   4980

ctgcccttct tgagagttcc ccctctttct gggtcaagag ctggagtggt ggctccatcc   5040

tctctgggcc acttcggtct aggaactcat ctttgcagga accaggagtc ctgagcacac   5100

tgaacacacc tcagagggag gatccttgtt gtggattttg cacctggctt tggggcaggg   5160

gtgaagtgac caggcttagc ttgtggagtt tatgggccac cagggtttgg ggaaatcacc   5220

atcccgcgga tgctgtgacc tcccttctac ggagatgcag gcagtgccac gagggaggag   5280

gggacctgca aagctagaat ctagggcact gtttcctccc catccttctc tttgtagaga   5340

atagagacgt ttgtcttgtc tgtcttcaac ctacttttcc ttttctcttt tttgtttctc   5400

atcctctctg tgccacctct ccacccagga ggccatgtag catagtggaa aaagtccctg   5460

agggcggtta ggagttctgg gtgaccatcc tggctcagct cctaactcac catgtgacat   5520

caggctatcc ccattccccc tcttgggcct cagtttcccg acttgcaaaa taagcagaaa   5580

gaaccagatg ctctccaggg tctttttcta ctttgctatc tcatgggtct tcattttctc   5640

ttattttgtt ttctctggat cttttccatc tgagggtaca ggaagtacca ggacctgttt   5700

cagtttttga atcctgcaag cacattccaa gactggcctg aaactgcatg agcaacatca   5760

ctcgaaataa tttttttttt caaaagcacc ttaacaacca attgcgatgc tgtcctgttc   5820

ctttttactc acacccttct ctcctttctc gtccccatgc tcccccacct cagtgctccg   5880

tgctgtatgc gtgtgctctc tgttcttgta tactcaatat aagtgaaata aatgtgtttg   5940

atgctgaacc ata                                                      5953


<210>  10060
<211>  779
<212>  PRT
<213>  Homo sapiens

<400>  10060

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val 
    50                  55                  60


Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe 
65                  70                  75                  80


Cys Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile 
                85                  90                  95


Lys Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys 
            100                 105                 110


Phe Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr 
        115                 120                 125


Tyr Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro 
    130                 135                 140


Cys Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala 
145                 150                 155                 160


Glu Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser 
                165                 170                 175


Glu Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile 
            180                 185                 190


Met Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu 
        195                 200                 205


Ile His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp 
    210                 215                 220


Leu His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val 
225                 230                 235                 240


Cys Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg 
                245                 250                 255


Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe 
            260                 265                 270


Tyr Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile 
        275                 280                 285


Gly Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val 
    290                 295                 300


Cys Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro 
305                 310                 315                 320


Pro Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
                325                 330                 335


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
            340                 345                 350


Pro Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser 
        355                 360                 365


Leu Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His 
    370                 375                 380


Asp Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly 
385                 390                 395                 400


Gly Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys 
                405                 410                 415


Ile Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys 
            420                 425                 430


His Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn 
        435                 440                 445


Ser Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu 
    450                 455                 460


Pro Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala 
465                 470                 475                 480


Asn Glu Arg Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro 
                485                 490                 495


Pro Arg Pro Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp 
            500                 505                 510


Gln Glu Arg Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu 
        515                 520                 525


Arg Lys Cys Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala 
    530                 535                 540


Glu Val Asp Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu 
545                 550                 555                 560


Asp Phe Ser Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser 
                565                 570                 575


Asp Thr Glu Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro 
            580                 585                 590


Ser Gln Asp Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly 
        595                 600                 605


Ala Cys Ser Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu 
    610                 615                 620


Thr Met Thr Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu 
625                 630                 635                 640


Ala Val Leu Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Glu Asn 
                645                 650                 655


Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro Gln 
            660                 665                 670


Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys Asp 
        675                 680                 685


Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr Ser 
    690                 695                 700


Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu Thr 
705                 710                 715                 720


Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp Gln 
                725                 730                 735


Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His Pro 
            740                 745                 750


Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro Ser 
        755                 760                 765


Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    770                 775


<210>  10061
<211>  6004
<212>  DNA
<213>  Homo sapiens

<400>  10061
cattattccg ggcacttctg gagggcctgg ccctgcccca ggagccctag ggcaggaatt     60

cctttcttta tctatagaag gcagacactt catccctgcc ccatcttctt tcagatgcta    120

tcttgggctc gctgaacacg ggtgcctgac tgacagaagt tcttgccccc ggggagctgg    180

tgtggacaga ggagggagcc tagacatgga ggagaaggac tacagtgagg ccgatggcct    240

ttcggagagg accacgccca gcaaggccca gaaatcgccc cagaagattg ccaagaaata    300

caagagtgcc atctgccggg tcactctgct tgatgcctcg gagtatgagt gtgaggtgga    360

gaaacatggc cggggccagg tgctgtttga cctggtctgt gaacacctca acctcctaga    420

gaaggactac ttcggcctga ccttctgtga tgctgacagc cagaagaact ggctggaccc    480

ctccaaggag atcaagaagc agatccggag tagcccctgg aattttgcct tcacagtcaa    540

gttctacccg cctgatcctg cccagctgac agaagacatc acaagatact acctgtgcct    600

gcagctgcgg gcagacatca tcacgggccg gctgccatgc tcctttgtca cgcatgccct    660

actgggctcc tacgctgtgc aggctgagct gggtgactat gatgctgagg agcatgtggg    720

caactatgtc agcgagctcc gcttcgcccc taaccagacc cgggagctgg aggagaggat    780

catggagctg cataagacat atagggggat gaccccggga gaagcagaaa tccacttctt    840

agagaatgcc aagaagcttt ccatgtacgg agtagacctg caccatgcca aggactctga    900

gggcatcgac atcatgttag gcgtttgtgc caatggcctg ctcatctacc gggaccggct    960

gagaatcaac cgctttgcct ggcccaagat cctcaagatc tcctacaaga ggagtaactt   1020

ctatatcaag atccggcctg gggagtatga gcaatttgag agcacaattg gctttaagct   1080

cccaaaccac cggtcagcca agagactgtg gaaggtctgc atcgagcatc atacattctt   1140

ccggctggtg tcccctgagc ccccacccaa gggcttcctg gtgatgggct ccaagttccg   1200

gtacagtggg aggacccagg cacagactcg ccaggccagc gccctcattg accggcctgc   1260

acccttcttt gagcgttctt ccagcaaacg gtacaccatg tcccgcagcc ttgatggagc   1320

agagttctcc cgcccagcct cggtcagcga gaaccatgat gcagggcctg acggtgacaa   1380

gcgggatgag gatggcgagt ctggggggca acggtcagag gctgaggagg gagaggtcag   1440

gactccaacc aagatcaagg agctaaagtt cttagacaag ccagaagatg tcttgctgaa   1500

gcaccaggcc agcatcaatg agctcaaaag gaccctgaag gagcccaaca gcaaactcat   1560

ccaccgggat cgagactggg aacgggagcg caggctgccc tcctcccccg cctccccctc   1620

ccccaagggc acccctgaga aagccaatga gagagcaggg ctgagggagg gctccgagga   1680

gaaagtcaaa ccaccacgtc cccgggcccc agagagtgac acaggcgatg aggaccagga   1740

ccaggagagg gacacggtgt tcctgaagga caaccacctg gccattgagc gcaagtgctc   1800

cagcatcacg gtcagctcta cgtctagcct ggaggctgag gtggacttca cggtcattgg   1860

tgactaccat ggcagcgcct tcgaagactt ctcccgcagc ctgcctgagc tcgaccggga   1920

caaaagcgac tcggacactg agggcctgct gttctcccgg gatctcaaca agggggcccc   1980

cagccaggat gatgagtctg ggggcattga ggacagcccg gatcgagggg cctgctccac   2040

cccggatatg ccccagtttg agcccgtgaa aacagaaacc atgactgtca gcagtctggc   2100

cattagaaag aagattgagc cggaggccgt actgcagacc agagtctccg ctatggataa   2160

cacccaggag aacagtctca agtccgggaa gggggcagct gccatgatcc caggcccaca   2220

gacggtggcc acggaaatcc gttctctttc tccgatcatc gggaaagatg tcctcaccag   2280

cacctacggc gccactgcgg aaaccctctc aacctccacc accacccatg tcaccaaaac   2340

tgtgaaagga gggttttctg agacaaggat cgagaagcga atcatcatta ctggggatga   2400

agatgtcgat caagaccagg ccctggcttt ggccatcaag gaggccaaac tgcagcatcc   2460

tgatatgctg gtaaccaaag ctgtcgtata cagagaaaca gacccatccc cagaggagag   2520

ggacaagaag ccacaggaat cctgacctct gtgaagagat cctggcattt ctggtccaac   2580

ccaagccaga gaaccattaa gaaggggcct tcattctgga ttctccgacg caacactgac   2640

gtcccagctg cgacgtactg tcactgatga gagactggga agggaaaagc atatatatat   2700

agatatatag agatatagat atatatacag gaaacaccgc atccttgcac tgctgctggg   2760

gctggcagag cagttggctg acagcaacaa ccgacatctg aacacctaca tttcctttgc   2820

agacaaattg aagaactggt gggatttttt tcaagaaaaa aaattatata ataactataa   2880

tcccttgctc acccctttcc cccgccaaat aagaaacgca agccagacca cgatgattgt   2940

agaagtccct cccgccctgg ttctgcacgt tacagttagc agacgagcaa ttccatttgt   3000

tcttctccag catctctaag gcccacttga atgcaaagga aaacacttgc acagcaaagc   3060

aagagaagtc acagcagcaa gacacgcaca gtcaaccatt ttccgagaaa aaaagaaaat   3120

tccccacttg gaaagaaaga ggaggaacac tggattctta ctttctggat cttgacactg   3180

ggctgcaaaa cctaccttcc tctctcccgc ctcccctcac cctcaactct caatgtcttg   3240

ctgtcatttt ctgtctcggc tccctcctcc cccttccccc ttcccccacc ccacaccctt   3300

caccctctgt gtcctggtcc ttctgagggc cactgcagat gactctcctt tgaaatgaga   3360

aaaagaaaag aaagcaagaa cagaaaacga agccacagga agggaagtag acattgtatg   3420

cttatggttt ctcattatga aggtgcagct tgtaggaggt ttgtacggat gtgctttgaa   3480

gttatgtata ttacatataa caggaaaaaa tattaaaata aacagtgctg gtaagtatga   3540

agctgacatt ctaaaattat aattatctga ctgtgattga tgtatcctga ggttcctaga   3600

tctcactgaa ctggcccagc taaggagacc tggactctgg gtgtgggttg gctcacagta   3660

ggggctgacg ggttcagtgt agtaatactg tgtgtggtgt ttgtaattgg ttgattggtg   3720

gggaggggtg gggggcccta atggagaggt gtgggtttgg caagaaagaa gcaacacaga   3780

tgtcgtcccc aaaatgccag ttcaagacac cttctccctg cccccctggt agtaacagtc   3840

agggcctggt ctgtgctcag gtactgggtc ccagtctggg actctgctgc tgaagttgcc   3900

acagtagagg tccctggctt agtccttatc tccctacggg gcttgccttg gttttcagtc   3960

ttctctctct ttctctcttt tttttttttt tgccacattc tgcccttccc tgaccccatt   4020

gtaataacca actccatatc caaagggagg tggtgctctc agccattgta gaagatggtg   4080

gctttaacct gactgtctaa aaattcccag ctaagccttt tcctctactc tcttccttgt   4140

tctgaatcat ttcttcttct caggccaaag tagccatggt aaggaggctt catggggcag   4200

accctgaaag atcaaaactg catttgcaaa gccctcccct gtcccaggac aaagctgaga   4260

ctgacgggtg atgttgctca taggctccag ctctgcataa gaccttggct tggagacctc   4320

cctctcagtc aacagctgaa ctctgagctt gtgcccagaa attaccccaa gaccacagga   4380

acccttcaag aagctcccat cacaagcttg gcattgctct ctgccacacg tgggcttcct   4440

caggcttgtc tgccacaagc tacttctctg agctcagaaa gtgccccttg atgagggaaa   4500

atgtcccact gcactgcgaa tttctcagtt ccattttacc tcccagtcct ccttctaaac   4560

cagttaataa attcattcca caagtattta ctgattacct gcttgtgcca gggactattc   4620

tcaggctgaa gaaggtggga ggggagggcg gaacctgagg agccacctga gccagcttta   4680

tatttcaacc atggctggcc catctgagag catctcccca ctctcgccaa cctatcgggg   4740

catagcccag ggatgccccc aggcggccca ggttagatgc gtccctttgg cttgtcagtg   4800

atgacataca ccttagctgc ttagctggtg ctggcctgag gcagggcagg aaatcagaat   4860

agcatttgct tctctgggca aatgggaagt tcagcggggc agcagaatca gtggcattcc   4920

ccctggtgca ggccggtggg tccactccaa ctccccctga gtgtagcagc acactttcca   4980

tacaccaggt tctttctaca atcctggtgg aaaagccaca gaaccttctt cctgcccttc   5040

ttgagagttc cccctctttc tgggtcaaga gctggagtgg tggctccatc ctctctgggc   5100

cacttcggtc taggaactca tctttgcagg aaccaggagt cctgagcaca ctgaacacac   5160

ctcagaggga ggatccttgt tgtggatttt gcacctggct ttggggcagg ggtgaagtga   5220

ccaggcttag cttgtggagt ttatgggcca ccagggtttg gggaaatcac catcccgcgg   5280

atgctgtgac ctcccttcta cggagatgca ggcagtgcca cgagggagga ggggacctgc   5340

aaagctagaa tctagggcac tgtttcctcc ccatccttct ctttgtagag aatagagacg   5400

tttgtcttgt ctgtcttcaa cctacttttc cttttctctt ttttgtttct catcctctct   5460

gtgccacctc tccacccagg aggccatgta gcatagtgga aaaagtccct gagggcggtt   5520

aggagttctg ggtgaccatc ctggctcagc tcctaactca ccatgtgaca tcaggctatc   5580

cccattcccc ctcttgggcc tcagtttccc gacttgcaaa ataagcagaa agaaccagat   5640

gctctccagg gtctttttct actttgctat ctcatgggtc ttcattttct cttattttgt   5700

tttctctgga tcttttccat ctgagggtac aggaagtacc aggacctgtt tcagtttttg   5760

aatcctgcaa gcacattcca agactggcct gaaactgcat gagcaacatc actcgaaata   5820

attttttttt tcaaaagcac cttaacaacc aattgcgatg ctgtcctgtt cctttttact   5880

cacacccttc tctcctttct cgtccccatg ctcccccacc tcagtgctcc gtgctgtatg   5940

cgtgtgctct ctgttcttgt atactcaata taagtgaaat aaatgtgttt gatgctgaac   6000

cata                                                                6004


<210>  10062
<211>  779
<212>  PRT
<213>  Homo sapiens

<400>  10062

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val 
    50                  55                  60


Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe 
65                  70                  75                  80


Cys Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile 
                85                  90                  95


Lys Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys 
            100                 105                 110


Phe Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr 
        115                 120                 125


Tyr Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro 
    130                 135                 140


Cys Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala 
145                 150                 155                 160


Glu Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser 
                165                 170                 175


Glu Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile 
            180                 185                 190


Met Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu 
        195                 200                 205


Ile His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp 
    210                 215                 220


Leu His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val 
225                 230                 235                 240


Cys Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg 
                245                 250                 255


Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe 
            260                 265                 270


Tyr Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile 
        275                 280                 285


Gly Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val 
    290                 295                 300


Cys Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro 
305                 310                 315                 320


Pro Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
                325                 330                 335


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
            340                 345                 350


Pro Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser 
        355                 360                 365


Leu Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His 
    370                 375                 380


Asp Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly 
385                 390                 395                 400


Gly Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys 
                405                 410                 415


Ile Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys 
            420                 425                 430


His Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn 
        435                 440                 445


Ser Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu 
    450                 455                 460


Pro Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala 
465                 470                 475                 480


Asn Glu Arg Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro 
                485                 490                 495


Pro Arg Pro Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp 
            500                 505                 510


Gln Glu Arg Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu 
        515                 520                 525


Arg Lys Cys Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala 
    530                 535                 540


Glu Val Asp Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu 
545                 550                 555                 560


Asp Phe Ser Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser 
                565                 570                 575


Asp Thr Glu Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro 
            580                 585                 590


Ser Gln Asp Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly 
        595                 600                 605


Ala Cys Ser Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu 
    610                 615                 620


Thr Met Thr Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu 
625                 630                 635                 640


Ala Val Leu Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Glu Asn 
                645                 650                 655


Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro Gln 
            660                 665                 670


Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys Asp 
        675                 680                 685


Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr Ser 
    690                 695                 700


Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu Thr 
705                 710                 715                 720


Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp Gln 
                725                 730                 735


Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His Pro 
            740                 745                 750


Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro Ser 
        755                 760                 765


Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    770                 775


<210>  10063
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  10063
agatgctatc ttgggctcgc tgaacacggg tgcctgactg acagaagttc ttgcccccgg     60

ggagctggtg tggacagagg aggggccctg gaagtgacca ctgggctgag tagctcatca    120

gcttccccac actgaagccc gaggggtctc ctgctggctt ctgagagctg acggaacagg    180

ttccagcaag gcagaccctg acacagaagc cagacctgtc cagcagggac cccatacact    240

gggaggcttc ctgggaaact ggaaggcaga agccacgcag acttctagtc ctggttccac    300

tgcttactcg gctgctgttc gtacctgcct catggttttc ttggggagga tcaatgaggt    360

agaacctgca aagggcttag cagagagcct agcacctact gagcgctcag taaaggcgtg    420

ctggtcacca tgacaacaga gacaggcccc gactctgagg tgaagaaagc tcaggaggag    480

gccccgcagc agcccgaggc tgctgccgct gtgaccaccc ctgtgacccc tgcaggccac    540

ggccacccag aggccaactc caatgagaag catccatccc agcaggaca                589


<210>  10064
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  10064

Met Val Phe Leu Gly Arg Ile Asn Glu Val Glu Pro Ala Lys Gly Leu 
1               5                   10                  15


Ala Glu Ser Leu Ala Pro Thr Glu Arg Ser Val Lys Ala Cys Trp Ser 
            20                  25                  30


Pro 



<210>  10065
<211>  593
<212>  DNA
<213>  Homo sapiens

<400>  10065
gagcgccgtg ggagggagag caggagcgag cgcgcgagag agcggggcat ttctgcgcag     60

ctctagcgcg cctcggagcc cgccggggca gccgccggac accaggaccg cgagccagac    120

agctcccgga agccgcgccg ccgccgccag gtagctcctt ggatattcct ttctgcaagt    180

gatcaggcaa agataaattc cattttacag atgaggaagc tgaggcctgt gaagggaaag    240

tgacctggct acacagccgg aacctgaatg caggacattc tgcccctgtc gtggtggtat    300

tggagccagc taatgccacc attcgaggtt gcaggagcag cacctgacca gaaatccaga    360

gcttgtgcct gactgacaga agttcttgcc cccggggagc tggtgtggac agaggagggg    420

cgtgctggtc accatgacaa cagagacagg ccccgactct gaggtgaaga aagctcagga    480

ggaggccccg cagcagcccg aggctgctgc cgctgtgacc acccctgtga cccctgcagg    540

ccacggccac ccagaggcca actccaatga gaagcatcca tcccagcagg aca           593


<210>  10066
<211>  34
<212>  PRT
<213>  Homo sapiens

<400>  10066

Met Gln Asp Ile Leu Pro Leu Ser Trp Trp Tyr Trp Ser Gln Leu Met 
1               5                   10                  15


Pro Pro Phe Glu Val Ala Gly Ala Ala Pro Asp Gln Lys Ser Arg Ala 
            20                  25                  30


Cys Ala 



<210>  10067
<211>  5987
<212>  DNA
<213>  Homo sapiens

<400>  10067
cgagcgcgcg agagagcggg gcatttctgc gcagctctag cgcgcctcgg agcccgccgg     60

ggcagccgcc ggacaccagg accgcgagcc agacagctcc cggaagccgc gccgccgccg    120

ccaggtgcct gactgacaga agttcttgcc cccggggagc tggtgtggac agaggaggga    180

gcctagacat ggaggagaag gactacagtg aggccgatgg cctttcggag aggaccacgc    240

ccagcaaggc ccagaaatcg ccccagaaga ttgccaagaa atacaagagt gccatctgcc    300

gggtcactct gcttgatgcc tcggagtatg agtgtgaggt ggagaaacat ggccggggcc    360

aggtgctgtt tgacctggtc tgtgaacacc tcaacctcct agagaaggac tacttcggcc    420

tgaccttctg tgatgctgac agccagaaga actggctgga cccctccaag gagatcaaga    480

agcagatccg gagtagcccc tggaattttg ccttcacagt caagttctac ccgcctgatc    540

ctgcccagct gacagaagac atcacaagat actacctgtg cctgcagctg cgggcagaca    600

tcatcacggg ccggctgcca tgctcctttg tcacgcatgc cctactgggc tcctacgctg    660

tgcaggctga gctgggtgac tatgatgctg aggagcatgt gggcaactat gtcagcgagc    720

tccgcttcgc ccctaaccag acccgggagc tggaggagag gatcatggag ctgcataaga    780

catatagggg gatgaccccg ggagaagcag aaatccactt cttagagaat gccaagaagc    840

tttccatgta cggagtagac ctgcaccatg ccaaggactc tgagggcatc gacatcatgt    900

taggcgtttg tgccaatggc ctgctcatct accgggaccg gctgagaatc aaccgctttg    960

cctggcccaa gatcctcaag atctcctaca agaggagtaa cttctatatc aagatccggc   1020

ctggggagta tgagcaattt gagagcacaa ttggctttaa gctcccaaac caccggtcag   1080

ccaagagact gtggaaggtc tgcatcgagc atcatacatt cttccggctg gtgtcccctg   1140

agcccccacc caagggcttc ctggtgatgg gctccaagtt ccggtacagt gggaggaccc   1200

aggcacagac tcgccaggcc agcgccctca ttgaccggcc tgcacccttc tttgagcgtt   1260

cttccagcaa acggtacacc atgtcccgca gccttgatgg agcagagttc tcccgcccag   1320

cctcggtcag cgagaaccat gatgcagggc ctgacggtga caagcgggat gaggatggcg   1380

agtctggggg gcaacggtca gaggctgagg agggagaggt caggactcca accaagatca   1440

aggagctaaa gttcttagac aagccagaag atgtcttgct gaagcaccag gccagcatca   1500

atgagctcaa aaggaccctg aaggagccca acagcaaact catccaccgg gatcgagact   1560

gggaacggga gcgcaggctg ccctcctccc ccgcctcccc ctcccccaag ggcacccctg   1620

agaaagccaa tgagagagca gggctgaggg agggctccga ggagaaagtc aaaccaccac   1680

gtccccgggc cccagagagt gacacaggcg atgaggacca ggaccaggag agggacacgg   1740

tgttcctgaa ggacaaccac ctggccattg agcgcaagtg ctccagcatc acggtcagct   1800

ctacgtctag cctggaggct gaggtggact tcacggtcat tggtgactac catggcagcg   1860

ccttcgaaga cttctcccgc agcctgcctg agctcgaccg ggacaaaagc gactcggaca   1920

ctgagggcct gctgttctcc cgggatctca acaagggggc ccccagccag gatgatgagt   1980

ctgggggcat tgaggacagc ccggatcgag gggcctgctc caccccggat atgccccagt   2040

ttgagcccgt gaaaacagaa accatgactg tcagcagtct ggccattaga aagaagattg   2100

agccggaggc cgtactgcag accagagtct ccgctatgga taacacccag gagaacagtc   2160

tcaagtccgg gaagggggca gctgccatga tcccaggccc acagacggtg gccacggaaa   2220

tccgttctct ttctccgatc atcgggaaag atgtcctcac cagcacctac ggcgccactg   2280

cggaaaccct ctcaacctcc accaccaccc atgtcaccaa aactgtgaaa ggagggtttt   2340

ctgagacaag gatcgagaag cgaatcatca ttactgggga tgaagatgtc gatcaagacc   2400

aggccctggc tttggccatc aaggaggcca aactgcagca tcctgatatg ctggtaacca   2460

aagctgtcgt atacagagaa acagacccat ccccagagga gagggacaag aagccacagg   2520

aatcctgacc tctgtgaaga gatcctggca tttctggtcc aacccaagcc agagaaccat   2580

taagaagggg ccttcattct ggattctccg acgcaacact gacgtcccag ctgcgacgta   2640

ctgtcactga tgagagactg ggaagggaaa agcatatata tatagatata tagagatata   2700

gatatatata caggaaacac cgcatccttg cactgctgct ggggctggca gagcagttgg   2760

ctgacagcaa caaccgacat ctgaacacct acatttcctt tgcagacaaa ttgaagaact   2820

ggtgggattt ttttcaagaa aaaaaattat ataataacta taatcccttg ctcacccctt   2880

tcccccgcca aataagaaac gcaagccaga ccacgatgat tgtagaagtc cctcccgccc   2940

tggttctgca cgttacagtt agcagacgag caattccatt tgttcttctc cagcatctct   3000

aaggcccact tgaatgcaaa ggaaaacact tgcacagcaa agcaagagaa gtcacagcag   3060

caagacacgc acagtcaacc attttccgag aaaaaaagaa aattccccac ttggaaagaa   3120

agaggaggaa cactggattc ttactttctg gatcttgaca ctgggctgca aaacctacct   3180

tcctctctcc cgcctcccct caccctcaac tctcaatgtc ttgctgtcat tttctgtctc   3240

ggctccctcc tcccccttcc cccttccccc accccacacc cttcaccctc tgtgtcctgg   3300

tccttctgag ggccactgca gatgactctc ctttgaaatg agaaaaagaa aagaaagcaa   3360

gaacagaaaa cgaagccaca ggaagggaag tagacattgt atgcttatgg tttctcatta   3420

tgaaggtgca gcttgtagga ggtttgtacg gatgtgcttt gaagttatgt atattacata   3480

taacaggaaa aaatattaaa ataaacagtg ctggtaagta tgaagctgac attctaaaat   3540

tataattatc tgactgtgat tgatgtatcc tgaggttcct agatctcact gaactggccc   3600

agctaaggag acctggactc tgggtgtggg ttggctcaca gtaggggctg acgggttcag   3660

tgtagtaata ctgtgtgtgg tgtttgtaat tggttgattg gtggggaggg gtggggggcc   3720

ctaatggaga ggtgtgggtt tggcaagaaa gaagcaacac agatgtcgtc cccaaaatgc   3780

cagttcaaga caccttctcc ctgcccccct ggtagtaaca gtcagggcct ggtctgtgct   3840

caggtactgg gtcccagtct gggactctgc tgctgaagtt gccacagtag aggtccctgg   3900

cttagtcctt atctccctac ggggcttgcc ttggttttca gtcttctctc tctttctctc   3960

tttttttttt ttttgccaca ttctgccctt ccctgacccc attgtaataa ccaactccat   4020

atccaaaggg aggtggtgct ctcagccatt gtagaagatg gtggctttaa cctgactgtc   4080

taaaaattcc cagctaagcc ttttcctcta ctctcttcct tgttctgaat catttcttct   4140

tctcaggcca aagtagccat ggtaaggagg cttcatgggg cagaccctga aagatcaaaa   4200

ctgcatttgc aaagccctcc cctgtcccag gacaaagctg agactgacgg gtgatgttgc   4260

tcataggctc cagctctgca taagaccttg gcttggagac ctccctctca gtcaacagct   4320

gaactctgag cttgtgccca gaaattaccc caagaccaca ggaacccttc aagaagctcc   4380

catcacaagc ttggcattgc tctctgccac acgtgggctt cctcaggctt gtctgccaca   4440

agctacttct ctgagctcag aaagtgcccc ttgatgaggg aaaatgtccc actgcactgc   4500

gaatttctca gttccatttt acctcccagt cctccttcta aaccagttaa taaattcatt   4560

ccacaagtat ttactgatta cctgcttgtg ccagggacta ttctcaggct gaagaaggtg   4620

ggaggggagg gcggaacctg aggagccacc tgagccagct ttatatttca accatggctg   4680

gcccatctga gagcatctcc ccactctcgc caacctatcg gggcatagcc cagggatgcc   4740

cccaggcggc ccaggttaga tgcgtccctt tggcttgtca gtgatgacat acaccttagc   4800

tgcttagctg gtgctggcct gaggcagggc aggaaatcag aatagcattt gcttctctgg   4860

gcaaatggga agttcagcgg ggcagcagaa tcagtggcat tccccctggt gcaggccggt   4920

gggtccactc caactccccc tgagtgtagc agcacacttt ccatacacca ggttctttct   4980

acaatcctgg tggaaaagcc acagaacctt cttcctgccc ttcttgagag ttccccctct   5040

ttctgggtca agagctggag tggtggctcc atcctctctg ggccacttcg gtctaggaac   5100

tcatctttgc aggaaccagg agtcctgagc acactgaaca cacctcagag ggaggatcct   5160

tgttgtggat tttgcacctg gctttggggc aggggtgaag tgaccaggct tagcttgtgg   5220

agtttatggg ccaccagggt ttggggaaat caccatcccg cggatgctgt gacctccctt   5280

ctacggagat gcaggcagtg ccacgaggga ggaggggacc tgcaaagcta gaatctaggg   5340

cactgtttcc tccccatcct tctctttgta gagaatagag acgtttgtct tgtctgtctt   5400

caacctactt ttccttttct cttttttgtt tctcatcctc tctgtgccac ctctccaccc   5460

aggaggccat gtagcatagt ggaaaaagtc cctgagggcg gttaggagtt ctgggtgacc   5520

atcctggctc agctcctaac tcaccatgtg acatcaggct atccccattc cccctcttgg   5580

gcctcagttt cccgacttgc aaaataagca gaaagaacca gatgctctcc agggtctttt   5640

tctactttgc tatctcatgg gtcttcattt tctcttattt tgttttctct ggatcttttc   5700

catctgaggg tacaggaagt accaggacct gtttcagttt ttgaatcctg caagcacatt   5760

ccaagactgg cctgaaactg catgagcaac atcactcgaa ataatttttt ttttcaaaag   5820

caccttaaca accaattgcg atgctgtcct gttccttttt actcacaccc ttctctcctt   5880

tctcgtcccc atgctccccc acctcagtgc tccgtgctgt atgcgtgtgc tctctgttct   5940

tgtatactca atataagtga aataaatgtg tttgatgctg aaccata                 5987


<210>  10068
<211>  779
<212>  PRT
<213>  Homo sapiens

<400>  10068

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val 
    50                  55                  60


Cys Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe 
65                  70                  75                  80


Cys Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile 
                85                  90                  95


Lys Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys 
            100                 105                 110


Phe Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr 
        115                 120                 125


Tyr Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro 
    130                 135                 140


Cys Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala 
145                 150                 155                 160


Glu Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser 
                165                 170                 175


Glu Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile 
            180                 185                 190


Met Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu 
        195                 200                 205


Ile His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp 
    210                 215                 220


Leu His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val 
225                 230                 235                 240


Cys Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg 
                245                 250                 255


Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe 
            260                 265                 270


Tyr Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile 
        275                 280                 285


Gly Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val 
    290                 295                 300


Cys Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro 
305                 310                 315                 320


Pro Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg 
                325                 330                 335


Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala 
            340                 345                 350


Pro Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser 
        355                 360                 365


Leu Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His 
    370                 375                 380


Asp Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly 
385                 390                 395                 400


Gly Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys 
                405                 410                 415


Ile Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys 
            420                 425                 430


His Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn 
        435                 440                 445


Ser Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu 
    450                 455                 460


Pro Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala 
465                 470                 475                 480


Asn Glu Arg Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro 
                485                 490                 495


Pro Arg Pro Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp 
            500                 505                 510


Gln Glu Arg Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu 
        515                 520                 525


Arg Lys Cys Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala 
    530                 535                 540


Glu Val Asp Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu 
545                 550                 555                 560


Asp Phe Ser Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser 
                565                 570                 575


Asp Thr Glu Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro 
            580                 585                 590


Ser Gln Asp Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly 
        595                 600                 605


Ala Cys Ser Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu 
    610                 615                 620


Thr Met Thr Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu 
625                 630                 635                 640


Ala Val Leu Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Glu Asn 
                645                 650                 655


Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro Gln 
            660                 665                 670


Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys Asp 
        675                 680                 685


Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr Ser 
    690                 695                 700


Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu Thr 
705                 710                 715                 720


Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp Gln 
                725                 730                 735


Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His Pro 
            740                 745                 750


Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro Ser 
        755                 760                 765


Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    770                 775


<210>  10069
<211>  3134
<212>  DNA
<213>  Homo sapiens

<400>  10069
gcatttctgc gcagctctag cgcgcctcgg agcccgccgg ggcagccgcc ggacaccagg     60

accgcgagcc agacagctcc cggaagccgc gccgccgccg ccaggtgcct gactgacaga    120

agttcttgcc cccggggagc tggtgtggac agaggagggg ccctggaagt gaccactggg    180

ctgagtagct catcagcttc cccacactga agcccgaggg gtctcctgct ggcttctgag    240

agctgacgga acaggttcca gcaaggcaga ccctgacaca gaagccagac ctgtccagca    300

gggaccccat acactgagcc tagacatgga ggagaaggac tacagtgagg ccgatggcct    360

ttcggagagg accacgccca gcaaggccca gaaatcgccc cagaagattg ccaagaaata    420

caagagtgcc atctgccggg tcactctgct tgatgcctcg gagtatgagt gtgaggtgga    480

gaactggctg gacccctcca aggagatcaa gaagcagatc cggagtagcc cctggaattt    540

tgccttcaca gtcaagttct acccgcctga tcctgcccag ctgacagaag acatcacaag    600

atactacctg tgcctgcagc tgcgggcaga catcatcacg ggccggctgc catgctcctt    660

tgtcacgcat gccctactgg gctcctacgc tgtgcaggct gagctgggtg actatgatgc    720

tgaggagcat gtgggcaact atgtcagcga gctccgcttc gcccctaacc agacccggga    780

gctggaggag aggatcatgg agctgcataa gacatatagg gggatgaccc cgggagaagc    840

agaaatccac ttcttagaga atgccaagaa gctttccatg tacggagtag acctgcacca    900

tgccaaggac tctgagggca tcgacatcat gttaggcgtt tgtgccaatg gcctgctcat    960

ctaccgggac cggctgagaa tcaaccgctt tgcctggccc aagatcctca agatctccta   1020

caagaggagt aacttctata tcaagatccg gcctggggag tatgagcaat ttgagagcac   1080

aattggcttt aagctcccaa accaccggtc agccaagaga ctgtggaagg tctgcatcga   1140

gcatcataca ttcttccggc tggtgtcccc tgagccccca cccaagggct tcctggtgat   1200

gggctccaag ttccggtaca gtgggaggac ccaggcacag actcgccagg ccagcgccct   1260

cattgaccgg cctgcaccct tctttgagcg ttcttccagc aaacggtaca ccatgtcccg   1320

cagccttgat ggagcagagt tctcccgccc agcctcggtc agcgagaacc atgatgcagg   1380

gcctgacggt gacaagcggg atgaggatgg cgagtctggg gggcaacggt cagaggctga   1440

ggagggagag gtcaggactc caaccaagat caaggagcta aagttcttag acaagccaga   1500

agatgtcttg ctgaagcacc aggccagcat caatgagctc aaaaggaccc tgaaggagcc   1560

caacagcaaa ctcatccacc gggatcgaga ctgggaacgg gagcgcaggc tgccctcctc   1620

ccccgcctcc ccctccccca agggcacccc tgagaaagcc aatgagagag cagggctgag   1680

ggagggctcc gaggagaaag tcaaaccacc acgtccccgg gccccagaga gtgacacagg   1740

cgatgaggac caggaccagg agagggacac ggtgttcctg aaggacaacc acctggccat   1800

tgagcgcaag tgctccagca tcacggtcag ctctacgtct agcctggagg ctgaggtgga   1860

cttcacggtc attggtgact accatggcag cgccttcgaa gacttctccc gcagcctgcc   1920

tgagctcgac cgggacaaaa gcgactcgga cactgagggc ctgctgttct cccgggatct   1980

caacaagggg gcccccagcc aggatgatga gtctgggggc attgaggaca gcccggatcg   2040

aggggcctgc tccaccccgg atatgcccca gtttgagccc gtgaaaacag aaaccatgac   2100

tgtcagcagt ctggccatta gaaagaagat tgagccggag gccgtactgc agaccagagt   2160

ctccgctatg gataacaccc aggttgatgg gagtgcctca gtggggaggg agttcatagc   2220

aaccactccc tccatcacca cggagaccat atcgaccacc atggagaaca gtctcaagtc   2280

cgggaagggg gcagctgcca tgatcccagg cccacagacg gtggccacgg aaatccgttc   2340

tctttctccg atcatcggga aagatgtcct caccagcacc tacggcgcca ctgcggaaac   2400

cctctcaacc tccaccacca cccatgtcac caaaactgtg aaaggagggt tttctgagac   2460

aaggatcgag aagcgaatca tcattactgg ggatgaagat gtcgatcaag accaggccct   2520

ggctttggcc atcaaggagg ccaaactgca gcatcctgat atgctggtaa ccaaagctgt   2580

cgtatacaga gaaacagacc catccccaga ggagagggac aagaagccac aggaatcctg   2640

acctctgtga agagatcctg gcatttctgg tccaacccaa gccagagaac cattaagaag   2700

gggccttcat tctggattct ccgacgcaac actgacgtcc cagctgcgac gtactgtcac   2760

tgatgagaga ctgggaaggg aaaagcatat atatatagat atatagagat atagatatat   2820

atacaggaaa caccgcatcc ttgcactgct gctggggctg gcagagcagt tggctgacag   2880

caacaaccga catctgaaca cctacatttc ctttgcagac aaattgaaga actggtggga   2940

tttttttcaa aaaagaaagc aagaacagaa aacgaagcca caggaaggga agtagacatt   3000

gtatgcttat ggtttctcat tatgaaggtg cagcttgtag gaggtttgta cggatgtgct   3060

ttgaagttat gtatattaca tataacagga aaaaatatta aaataaacag tgctggtaag   3120

tatgaagctg acat                                                     3134


<210>  10070
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  10070

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys Lys Gln 
    50                  55                  60


Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe Tyr Pro 
65                  70                  75                  80


Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu Cys 
                85                  90                  95


Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys Ser Phe 
            100                 105                 110


Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu Leu Gly 
        115                 120                 125


Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu Leu Arg 
    130                 135                 140


Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met Glu Leu 
145                 150                 155                 160


His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile His Phe 
                165                 170                 175


Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His His 
            180                 185                 190


Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys Ala Asn 
        195                 200                 205


Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala Trp 
    210                 215                 220


Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr Ile Lys 
225                 230                 235                 240


Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly Phe Lys 
                245                 250                 255


Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys Ile Glu 
            260                 265                 270


His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro Lys Gly 
        275                 280                 285


Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala 
    290                 295                 300


Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro Phe Phe 
305                 310                 315                 320


Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu Asp Gly 
                325                 330                 335


Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp Ala Gly 
            340                 345                 350


Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly Gln Arg 
        355                 360                 365


Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile Lys Glu 
    370                 375                 380


Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His Gln Ala 
385                 390                 395                 400


Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser Lys Leu 
                405                 410                 415


Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro Ser Ser 
            420                 425                 430


Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn Glu Arg 
        435                 440                 445


Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro Pro Arg Pro 
    450                 455                 460


Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp Gln Glu Arg 
465                 470                 475                 480


Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu Arg Lys Cys 
                485                 490                 495


Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala Glu Val Asp 
            500                 505                 510


Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu Asp Phe Ser 
        515                 520                 525


Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser Asp Thr Glu 
    530                 535                 540


Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro Ser Gln Asp 
545                 550                 555                 560


Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly Ala Cys Ser 
                565                 570                 575


Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu Thr Met Thr 
            580                 585                 590


Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu Ala Val Leu 
        595                 600                 605


Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Val Asp Gly Ser Ala 
    610                 615                 620


Ser Val Gly Arg Glu Phe Ile Ala Thr Thr Pro Ser Ile Thr Thr Glu 
625                 630                 635                 640


Thr Ile Ser Thr Thr Met Glu Asn Ser Leu Lys Ser Gly Lys Gly Ala 
                645                 650                 655


Ala Ala Met Ile Pro Gly Pro Gln Thr Val Ala Thr Glu Ile Arg Ser 
            660                 665                 670


Leu Ser Pro Ile Ile Gly Lys Asp Val Leu Thr Ser Thr Tyr Gly Ala 
        675                 680                 685


Thr Ala Glu Thr Leu Ser Thr Ser Thr Thr Thr His Val Thr Lys Thr 
    690                 695                 700


Val Lys Gly Gly Phe Ser Glu Thr Arg Ile Glu Lys Arg Ile Ile Ile 
705                 710                 715                 720


Thr Gly Asp Glu Asp Val Asp Gln Asp Gln Ala Leu Ala Leu Ala Ile 
                725                 730                 735


Lys Glu Ala Lys Leu Gln His Pro Asp Met Leu Val Thr Lys Ala Val 
            740                 745                 750


Val Tyr Arg Glu Thr Asp Pro Ser Pro Glu Glu Arg Asp Lys Lys Pro 
        755                 760                 765


Gln Glu Ser 
    770


<210>  10071
<211>  5589
<212>  DNA
<213>  Homo sapiens

<400>  10071
gcatttctgc gcagctctag cgcgcctcgg agcccgccgg ggcagccgcc ggacaccagg     60

accgcgagcc agacagctcc cggaagccgc gccgccgccg ccaggtgcct gactgacaga    120

agttcttgcc cccggggagc tggtgtggac agaggagggg ccctggaagt gaccactggg    180

ctgagtagct catcagcttc cccacactga agcccgaggg gtctcctgct ggcttctgag    240

agctgacgga acaggttcca gcaaggcaga ccctgacaca gaagccagac ctgtccagca    300

gggaccccat acactgagcc tagacatgga ggagaaggac tacagtgagg ccgatggcct    360

ttcggagagg accacgccca gcaaggccca gaaatcgccc cagaagattg ccaagaaata    420

caagagtgcc atctgccggg tcactctgct tgatgcctcg gagtatgagt gtgaggtgga    480

gaactggctg gacccctcca aggagatcaa gaagcagatc cggagtagcc cctggaattt    540

tgccttcaca gtcaagttct acccgcctga tcctgcccag ctgacagaag acatcacaag    600

atactacctg tgcctgcagc tgcgggcaga catcatcacg ggccggctgc catgctcctt    660

tgtcacgcat gccctactgg gctcctacgc tgtgcaggct gagctgggtg actatgatgc    720

tgaggagcat gtgggcaact atgtcagcga gctccgcttc gcccctaacc agacccggga    780

gctggaggag aggatcatgg agctgcataa gacatatagg gggatgaccc cgggagaagc    840

agaaatccac ttcttagaga atgccaagaa gctttccatg tacggagtag acctgcacca    900

tgccaaggac tctgagggca tcgacatcat gttaggcgtt tgtgccaatg gcctgctcat    960

ctaccgggac cggctgagaa tcaaccgctt tgcctggccc aagatcctca agatctccta   1020

caagaggagt aacttctata tcaagatccg gcctggggag tatgagcaat ttgagagcac   1080

aattggcttt aagctcccaa accaccggtc agccaagaga ctgtggaagg tctgcatcga   1140

gcatcataca ttcttccggc tggtgtcccc tgagccccca cccaagggct tcctggtgat   1200

gggctccaag ttccggtaca gtgggaggac ccaggcacag actcgccagg ccagcgccct   1260

cattgaccgg cctgcaccct tctttgagcg ttcttccagc aaacggtaca ccatgtcccg   1320

cagccttgat ggagcagagt tctcccgccc agcctcggtc agcgagaacc atgatgcagg   1380

gcctgacggt gacaagcggg atgaggatgg cgagtctggg gggcaacggt cagaggctga   1440

ggagggagag gtcaggactc caaccaagat caaggagcta aagttcttag acaagccaga   1500

agatgtcttg ctgaagcacc aggccagcat caatgagctc aaaaggaccc tgaaggagcc   1560

caacagcaaa ctcatccacc gggatcgaga ctgggaacgg gagcgcaggc tgccctcctc   1620

ccccgcctcc ccctccccca agggcacccc tgagaaagcc aatgagagag cagggctgag   1680

ggagggctcc gaggagaaag tcaaaccacc acgtccccgg gccccagaga gtgacacagg   1740

cgatgaggac caggaccagg agagggacac ggtgttcctg aaggacaacc acctggccat   1800

tgagcgcaag tgctccagca tcacggtcag ctctacgtct agcctggagg ctgaggtgga   1860

cttcacggtc attggtgact accatggcag cgccttcgaa gacttctccc gcagcctgcc   1920

tgagctcgac cgggacaaaa gcgactcgga cactgagggc ctgctgttct cccgggatct   1980

caacaagggg gcccccagcc aggatgatga gtctgggggc attgaggaca gcccggatcg   2040

aggggcctgc tccaccccgg atatgcccca gtttgagccc gtgaaaacag aaaccatgac   2100

tgtcagcagt ctggccatta gaaagaagat tgagccggag gccgtactgc agaccagagt   2160

ctccgctatg gataacaccc aggttgatgg gagtgcctca gtggggaggg agttcatagc   2220

aaccactccc tccatcacca cggagaccat atcgaccacc atggagaaca gtctcaagtc   2280

cgggaagggg gcagctgcca tgatcccagg cccacagacg gtggccacgg aaatccgttc   2340

tctttctccg atcatcggga aagatgtcct caccagcacc tacggcgcca ctgcggaaac   2400

cctctcaacc tccaccacca cccatgtcac caaaactgtg aaaggagggt tttctgagac   2460

aaggatcgag aagcgaatca tcattactgg ggatgaagat gtcgatcaag accaggccct   2520

ggctttggcc atcaaggagg ccaaactgca gcatcctgat atgctggtaa ccaaagctgt   2580

cgtatacaga gaaacagacc catccccaga ggagagggac aagaagccac aggaatcctg   2640

acctctgtga agagatcctg gcatttctgg tccaacccaa gccagagaac cattaagaag   2700

gggccttcat tctggattct ccgacgcaac actgacgtcc cagctgcgac gtactgtcac   2760

tgatgagaga ctgggaaggg aaaagcatat atatatagat atatagagat atagatatat   2820

atacaggaaa caccgcatcc ttgcactgct gctggggctg gcagagcagt tggctgacag   2880

caacaaccga catctgaaca cctacatttc ctttgcagac aaattgaaga actggtggga   2940

tttttttcaa aaaagaaagc aagaacagaa aacgaagcca caggaaggga agtagacatt   3000

gtatgcttat ggtttctcat tatgaaggtg cagcttgtag gaggtttgta cggatgtgct   3060

ttgaagttat gtatattaca tataacagga aaaaatatta aaataaacag tgctggtaag   3120

tatgaagctg acattctaaa attataatta tctgactgtg attgatgtat cctgaggttc   3180

ctagatctca ctgaactggc ccagctaagg agacctggac tctgggtgtg ggttggctca   3240

cagtaggggc tgacgggttc agtgtagtaa tactgtgtgt ggtgtttgta attggttgat   3300

tggtggggag gggtgggggg ccctaatgga gaggtgtggg tttggcaaga aagaagcaac   3360

acagatgtcg tccccaaaat gccagttcaa gacaccttct ccctgccccc ctggtagtaa   3420

cagtcagggc ctggtctgtg ctcaggtact gggtcccagt ctgggactct gctgctgaag   3480

ttgccacagt agaggtccct ggcttagtcc ttatctccct acggggcttg ccttggtttt   3540

cagtcttctc tctctttctc tctttttttt ttttttgcca cattctgccc ttccctgacc   3600

ccattgtaat aaccaactcc atatccaaag ggaggtggtg ctctcagcca ttgtagaaga   3660

tggtggcttt aacctgactg tctaaaaatt cccagctaag ccttttcctc tactctcttc   3720

cttgttctga atcatttctt cttctcaggc caaagtagcc atggtaagga ggcttcatgg   3780

ggcagaccct gaaagatcaa aactgcattt gcaaagccct cccctgtccc aggacaaagc   3840

tgagactgac gggtgatgtt gctcataggc tccagctctg cataagacct tggcttggag   3900

acctccctct cagtcaacag ctgaactctg agcttgtgcc cagaaattac cccaagacca   3960

caggaaccct tcaagaagct cccatcacaa gcttggcatt gctctctgcc acacgtgggc   4020

ttcctcaggc ttgtctgcca caagctactt ctctgagctc agaaagtgcc ccttgatgag   4080

ggaaaatgtc ccactgcact gcgaatttct cagttccatt ttacctccca gtcctccttc   4140

taaaccagtt aataaattca ttccacaagt atttactgat tacctgcttg tgccagggac   4200

tattctcagg ctgaagaagg tgggagggga gggcggaacc tgaggagcca cctgagccag   4260

ctttatattt caaccatggc tggcccatct gagagcatct ccccactctc gccaacctat   4320

cggggcatag cccagggatg cccccaggcg gcccaggtta gatgcgtccc tttggcttgt   4380

cagtgatgac atacacctta gctgcttagc tggtgctggc ctgaggcagg gcaggaaatc   4440

agaatagcat ttgcttctct gggcaaatgg gaagttcagc ggggcagcag aatcagtggc   4500

attccccctg gtgcaggccg gtgggtccac tccaactccc cctgagtgta gcagcacact   4560

ttccatacac caggttcttt ctacaatcct ggtggaaaag ccacagaacc ttcttcctgc   4620

ccttcttgag agttccccct ctttctgggt caagagctgg agtggtggct ccatcctctc   4680

tgggccactt cggtctagga actcatcttt gcaggaacca ggagtcctga gcacactgaa   4740

cacacctcag agggaggatc cttgttgtgg attttgcacc tggctttggg gcaggggtga   4800

agtgaccagg cttagcttgt ggagtttatg ggccaccagg gtttggggaa atcaccatcc   4860

cgcggatgct gtgacctccc ttctacggag atgcaggcag tgccacgagg gaggagggga   4920

cctgcaaagc tagaatctag ggcactgttt cctccccatc cttctctttg tagagaatag   4980

agacgtttgt cttgtctgtc ttcaacctac ttttcctttt ctcttttttg tttctcatcc   5040

tctctgtgcc acctctccac ccaggaggcc atgtagcata gtggaaaaag tccctgaggg   5100

cggttaggag ttctgggtga ccatcctggc tcagctccta actcaccatg tgacatcagg   5160

ctatccccat tccccctctt gggcctcagt ttcccgactt gcaaaataag cagaaagaac   5220

cagatgctct ccagggtctt tttctacttt gctatctcat gggtcttcat tttctcttat   5280

tttgttttct ctggatcttt tccatctgag ggtacaggaa gtaccaggac ctgtttcagt   5340

ttttgaatcc tgcaagcaca ttccaagact ggcctgaaac tgcatgagca acatcactcg   5400

aaataatttt ttttttcaaa agcaccttaa caaccaattg cgatgctgtc ctgttccttt   5460

ttactcacac ccttctctcc tttctcgtcc ccatgctccc ccacctcagt gctccgtgct   5520

gtatgcgtgt gctctctgtt cttgtatact caatataagt gaaataaatg tgtttgatgc   5580

tgaaccata                                                           5589


<210>  10072
<211>  771
<212>  PRT
<213>  Homo sapiens

<400>  10072

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr 
            20                  25                  30


Lys Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu 
        35                  40                  45


Cys Glu Val Glu Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys Lys Gln 
    50                  55                  60


Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe Tyr Pro 
65                  70                  75                  80


Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu Cys 
                85                  90                  95


Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys Ser Phe 
            100                 105                 110


Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu Leu Gly 
        115                 120                 125


Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu Leu Arg 
    130                 135                 140


Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met Glu Leu 
145                 150                 155                 160


His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile His Phe 
                165                 170                 175


Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His His 
            180                 185                 190


Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys Ala Asn 
        195                 200                 205


Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala Trp 
    210                 215                 220


Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr Ile Lys 
225                 230                 235                 240


Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly Phe Lys 
                245                 250                 255


Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys Ile Glu 
            260                 265                 270


His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro Lys Gly 
        275                 280                 285


Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln Ala 
    290                 295                 300


Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro Phe Phe 
305                 310                 315                 320


Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu Asp Gly 
                325                 330                 335


Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp Ala Gly 
            340                 345                 350


Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly Gln Arg 
        355                 360                 365


Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile Lys Glu 
    370                 375                 380


Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His Gln Ala 
385                 390                 395                 400


Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser Lys Leu 
                405                 410                 415


Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro Ser Ser 
            420                 425                 430


Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn Glu Arg 
        435                 440                 445


Ala Gly Leu Arg Glu Gly Ser Glu Glu Lys Val Lys Pro Pro Arg Pro 
    450                 455                 460


Arg Ala Pro Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp Gln Glu Arg 
465                 470                 475                 480


Asp Thr Val Phe Leu Lys Asp Asn His Leu Ala Ile Glu Arg Lys Cys 
                485                 490                 495


Ser Ser Ile Thr Val Ser Ser Thr Ser Ser Leu Glu Ala Glu Val Asp 
            500                 505                 510


Phe Thr Val Ile Gly Asp Tyr His Gly Ser Ala Phe Glu Asp Phe Ser 
        515                 520                 525


Arg Ser Leu Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser Asp Thr Glu 
    530                 535                 540


Gly Leu Leu Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro Ser Gln Asp 
545                 550                 555                 560


Asp Glu Ser Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly Ala Cys Ser 
                565                 570                 575


Thr Pro Asp Met Pro Gln Phe Glu Pro Val Lys Thr Glu Thr Met Thr 
            580                 585                 590


Val Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu Ala Val Leu 
        595                 600                 605


Gln Thr Arg Val Ser Ala Met Asp Asn Thr Gln Val Asp Gly Ser Ala 
    610                 615                 620


Ser Val Gly Arg Glu Phe Ile Ala Thr Thr Pro Ser Ile Thr Thr Glu 
625                 630                 635                 640


Thr Ile Ser Thr Thr Met Glu Asn Ser Leu Lys Ser Gly Lys Gly Ala 
                645                 650                 655


Ala Ala Met Ile Pro Gly Pro Gln Thr Val Ala Thr Glu Ile Arg Ser 
            660                 665                 670


Leu Ser Pro Ile Ile Gly Lys Asp Val Leu Thr Ser Thr Tyr Gly Ala 
        675                 680                 685


Thr Ala Glu Thr Leu Ser Thr Ser Thr Thr Thr His Val Thr Lys Thr 
    690                 695                 700


Val Lys Gly Gly Phe Ser Glu Thr Arg Ile Glu Lys Arg Ile Ile Ile 
705                 710                 715                 720


Thr Gly Asp Glu Asp Val Asp Gln Asp Gln Ala Leu Ala Leu Ala Ile 
                725                 730                 735


Lys Glu Ala Lys Leu Gln His Pro Asp Met Leu Val Thr Lys Ala Val 
            740                 745                 750


Val Tyr Arg Glu Thr Asp Pro Ser Pro Glu Glu Arg Asp Lys Lys Pro 
        755                 760                 765


Gln Glu Ser 
    770


<210>  10073
<211>  3296
<212>  DNA
<213>  Homo sapiens

<400>  10073
atttctgcgc agctctagcg cgcctcggag cccgccgggg cagccgccgg acaccaggac     60

cgcgagccag acagctcccg gaagccgcgc cgccgccgcc aggtgcctga ctgacagaag    120

ttcttgcccc cggggagctg gtgtggacag aggaggggct gctgttcgta cctgcctcat    180

ggttttcttg gggaggatca atgaggtaga acctgcaaag ggcttagcag agagcctagc    240

acctactgag cgctcagtaa agagcctaga catggaggag aaggactaca gtgaggccga    300

tggcctttcg gagaggacca cgcccagcaa ggcccagaaa tcgccccaga agattgccaa    360

gaaatacaag agtgccatct gccgggtcac tctgcttgat gcctcggagt atgagtgtga    420

ggtggagaaa catggccggg gccaggtgct gtttgacctg gtctgtgaac acctcaacct    480

cctagagaag gactacttcg gcctgacctt ctgtgatgct gacagccaga agaactggct    540

ggacccctcc aaggagatca agaagcagat ccggagtagc ccctggaatt ttgccttcac    600

agtcaagttc tacccgcctg atcctgccca gctgacagaa gacatcacaa gatactacct    660

gtgcctgcag ctgcgggcag acatcatcac gggccggctg ccatgctcct ttgtcacgca    720

tgccctactg ggctcctacg ctgtgcaggc tgagctgggt gactatgatg ctgaggagca    780

tgtgggcaac tatgtcagcg agctccgctt cgcccctaac cagacccggg agctggagga    840

gaggatcatg gagctgcata agacatatag ggggatgacc ccgggagaag cagaaatcca    900

cttcttagag aatgccaaga agctttccat gtacggagta gacctgcacc atgccaagga    960

ctctgagggc atcgacatca tgttaggcgt ttgtgccaat ggcctgctca tctaccggga   1020

ccggctgaga atcaaccgct ttgcctggcc caagatcctc aagatctcct acaagaggag   1080

taacttctat atcaagatcc ggcctgggga gtatgagcaa tttgagagca caattggctt   1140

taagctccca aaccaccggt cagccaagag actgtggaag gtctgcatcg agcatcatac   1200

attcttccgg ctggtgtccc ctgagccccc acccaagggc ttcctggtga tgggctccaa   1260

gttccggtac agtgggagga cccaggcaca gactcgccag gccagcgccc tcattgaccg   1320

gcctgcaccc ttctttgagc gttcttccag caaacggtac accatgtccc gcagccttga   1380

tggagcagag ttctcccgcc cagcctcggt cagcgagaac catgatgcag ggcctgacgg   1440

tgacaagcgg gatgaggatg gcgagtctgg ggggcaacgg tcagaggctg aggagggaga   1500

ggtcaggact ccaaccaaga tcaaggagct aaagttctta gacaagccag aagatgtctt   1560

gctgaagcac caggccagca tcaatgagct caaaaggacc ctgaaggagc ccaacagcaa   1620

actcatccac cgggatcgag actgggaacg ggagcgcagg ctgccctcct cccccgcctc   1680

cccctccccc aagggcaccc ctgagaaagc caatgagccc gtgaaaacag aaaccatgac   1740

tgtcagcagt ctggccatta gaaagaagat tgagccggag gccgtactgc agaccagagt   1800

ctccgctatg gataacaccc aggttgatgg gagtgcctca gtggggaggg agttcatagc   1860

aaccactccc tccatcacca cggagaccat atcgaccacc atggagaaca gtctcaagtc   1920

cgggaagggg gcagctgcca tgatcccagg cccacagacg gtggccacgg aaatccgttc   1980

tctttctccg atcatcggga aagatgtcct caccagcacc tacggcgcca ctgcggaaac   2040

cctctcaacc tccaccacca cccatgtcac caaaactgtg aaaggagggt tttctgagac   2100

aaggatcgag aagcgaatca tcattactgg ggatgaagat gtcgatcaag accaggccct   2160

ggctttggcc atcaaggagg ccaaactgca gcatcctgat atgctggtaa ccaaagctgt   2220

cgtatacaga gaaacagacc catccccaga ggagagggac aagaagccac aggaatcctg   2280

acctctgtga agagatcctg gcatttctgg tccaacccaa gccagagaac cattaagaag   2340

gggccttcat tctggattct ccgacgcaac actgacgtcc cagctgcgac gtactgtcac   2400

tgatgagaga ctgggaaggg aaaagcatat atatatagat atatagagat atagatatat   2460

atacaggaaa caccgcatcc ttgcactgct gctggggctg gcagagcagt tggctgacag   2520

caacaaccga catctgaaca cctacatttc ctttgcagac aaattgaaga actggtggga   2580

tttttttcaa gaaaaaaaat tatataataa ctataatccc ttgctcaccc ctttcccccg   2640

ccaaataaga aacgcaagcc agaccacgat gattgtagaa gtccctcccg ccctggttct   2700

gcacgttaca gttagcagac gagcaattcc atttgttctt ctccagcatc tctaaggccc   2760

acttgaatgc aaaggaaaac acttgcacag caaagcaaga gaagtcacag cagcaagaca   2820

cgcacagtca accattttcc gagaaaaaaa gaaaattccc cacttggaaa gaaagaggag   2880

gaacactgga ttcttacttt ctggatcttg acactgggct gcaaaaccta ccttcctctc   2940

tcccgcctcc cctcaccctc aactctcaat gtcttgctgt cattttctgt ctcggctccc   3000

tcctccccct tcccccttcc cccaccccac acccttcacc ctctgtgtcc tggtccttct   3060

gagggccact gcagatgact ctcctttgaa atgagaaaaa gaaaagaaag caagaacaga   3120

aaacgaagcc acaggaaggg aagtagacat tgtatgctta tggtttctca ttatgaaggt   3180

gcagcttgta ggaggtttgt acggatgtgc tttgaagtta tgtatattac atataacagg   3240

aaaaaatatt aaaataaaca gtgctggtaa gtatgaagct gacattctaa aattat       3296


<210>  10074
<211>  700
<212>  PRT
<213>  Homo sapiens

<400>  10074

Met Val Phe Leu Gly Arg Ile Asn Glu Val Glu Pro Ala Lys Gly Leu 
1               5                   10                  15


Ala Glu Ser Leu Ala Pro Thr Glu Arg Ser Val Lys Ser Leu Asp Met 
            20                  25                  30


Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr Thr 
        35                  40                  45


Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr Lys 
    50                  55                  60


Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu Cys 
65                  70                  75                  80


Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val Cys 
                85                  90                  95


Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe Cys 
            100                 105                 110


Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys 
        115                 120                 125


Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe 
    130                 135                 140


Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr 
145                 150                 155                 160


Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys 
                165                 170                 175


Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu 
            180                 185                 190


Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu 
        195                 200                 205


Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met 
    210                 215                 220


Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile 
225                 230                 235                 240


His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu 
                245                 250                 255


His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys 
            260                 265                 270


Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe 
        275                 280                 285


Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr 
    290                 295                 300


Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly 
305                 310                 315                 320


Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys 
                325                 330                 335


Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro 
            340                 345                 350


Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr 
        355                 360                 365


Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro 
    370                 375                 380


Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu 
385                 390                 395                 400


Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp 
                405                 410                 415


Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly 
            420                 425                 430


Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile 
        435                 440                 445


Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His 
    450                 455                 460


Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser 
465                 470                 475                 480


Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro 
                485                 490                 495


Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn 
            500                 505                 510


Glu Pro Val Lys Thr Glu Thr Met Thr Val Ser Ser Leu Ala Ile Arg 
        515                 520                 525


Lys Lys Ile Glu Pro Glu Ala Val Leu Gln Thr Arg Val Ser Ala Met 
    530                 535                 540


Asp Asn Thr Gln Val Asp Gly Ser Ala Ser Val Gly Arg Glu Phe Ile 
545                 550                 555                 560


Ala Thr Thr Pro Ser Ile Thr Thr Glu Thr Ile Ser Thr Thr Met Glu 
                565                 570                 575


Asn Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro 
            580                 585                 590


Gln Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys 
        595                 600                 605


Asp Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr 
    610                 615                 620


Ser Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu 
625                 630                 635                 640


Thr Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp 
                645                 650                 655


Gln Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His 
            660                 665                 670


Pro Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro 
        675                 680                 685


Ser Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    690                 695                 700


<210>  10075
<211>  5740
<212>  DNA
<213>  Homo sapiens

<400>  10075
atttctgcgc agctctagcg cgcctcggag cccgccgggg cagccgccgg acaccaggac     60

cgcgagccag acagctcccg gaagccgcgc cgccgccgcc aggtgcctga ctgacagaag    120

ttcttgcccc cggggagctg gtgtggacag aggaggggct gctgttcgta cctgcctcat    180

ggttttcttg gggaggatca atgaggtaga acctgcaaag ggcttagcag agagcctagc    240

acctactgag cgctcagtaa agagcctaga catggaggag aaggactaca gtgaggccga    300

tggcctttcg gagaggacca cgcccagcaa ggcccagaaa tcgccccaga agattgccaa    360

gaaatacaag agtgccatct gccgggtcac tctgcttgat gcctcggagt atgagtgtga    420

ggtggagaaa catggccggg gccaggtgct gtttgacctg gtctgtgaac acctcaacct    480

cctagagaag gactacttcg gcctgacctt ctgtgatgct gacagccaga agaactggct    540

ggacccctcc aaggagatca agaagcagat ccggagtagc ccctggaatt ttgccttcac    600

agtcaagttc tacccgcctg atcctgccca gctgacagaa gacatcacaa gatactacct    660

gtgcctgcag ctgcgggcag acatcatcac gggccggctg ccatgctcct ttgtcacgca    720

tgccctactg ggctcctacg ctgtgcaggc tgagctgggt gactatgatg ctgaggagca    780

tgtgggcaac tatgtcagcg agctccgctt cgcccctaac cagacccggg agctggagga    840

gaggatcatg gagctgcata agacatatag ggggatgacc ccgggagaag cagaaatcca    900

cttcttagag aatgccaaga agctttccat gtacggagta gacctgcacc atgccaagga    960

ctctgagggc atcgacatca tgttaggcgt ttgtgccaat ggcctgctca tctaccggga   1020

ccggctgaga atcaaccgct ttgcctggcc caagatcctc aagatctcct acaagaggag   1080

taacttctat atcaagatcc ggcctgggga gtatgagcaa tttgagagca caattggctt   1140

taagctccca aaccaccggt cagccaagag actgtggaag gtctgcatcg agcatcatac   1200

attcttccgg ctggtgtccc ctgagccccc acccaagggc ttcctggtga tgggctccaa   1260

gttccggtac agtgggagga cccaggcaca gactcgccag gccagcgccc tcattgaccg   1320

gcctgcaccc ttctttgagc gttcttccag caaacggtac accatgtccc gcagccttga   1380

tggagcagag ttctcccgcc cagcctcggt cagcgagaac catgatgcag ggcctgacgg   1440

tgacaagcgg gatgaggatg gcgagtctgg ggggcaacgg tcagaggctg aggagggaga   1500

ggtcaggact ccaaccaaga tcaaggagct aaagttctta gacaagccag aagatgtctt   1560

gctgaagcac caggccagca tcaatgagct caaaaggacc ctgaaggagc ccaacagcaa   1620

actcatccac cgggatcgag actgggaacg ggagcgcagg ctgccctcct cccccgcctc   1680

cccctccccc aagggcaccc ctgagaaagc caatgagccc gtgaaaacag aaaccatgac   1740

tgtcagcagt ctggccatta gaaagaagat tgagccggag gccgtactgc agaccagagt   1800

ctccgctatg gataacaccc aggttgatgg gagtgcctca gtggggaggg agttcatagc   1860

aaccactccc tccatcacca cggagaccat atcgaccacc atggagaaca gtctcaagtc   1920

cgggaagggg gcagctgcca tgatcccagg cccacagacg gtggccacgg aaatccgttc   1980

tctttctccg atcatcggga aagatgtcct caccagcacc tacggcgcca ctgcggaaac   2040

cctctcaacc tccaccacca cccatgtcac caaaactgtg aaaggagggt tttctgagac   2100

aaggatcgag aagcgaatca tcattactgg ggatgaagat gtcgatcaag accaggccct   2160

ggctttggcc atcaaggagg ccaaactgca gcatcctgat atgctggtaa ccaaagctgt   2220

cgtatacaga gaaacagacc catccccaga ggagagggac aagaagccac aggaatcctg   2280

acctctgtga agagatcctg gcatttctgg tccaacccaa gccagagaac cattaagaag   2340

gggccttcat tctggattct ccgacgcaac actgacgtcc cagctgcgac gtactgtcac   2400

tgatgagaga ctgggaaggg aaaagcatat atatatagat atatagagat atagatatat   2460

atacaggaaa caccgcatcc ttgcactgct gctggggctg gcagagcagt tggctgacag   2520

caacaaccga catctgaaca cctacatttc ctttgcagac aaattgaaga actggtggga   2580

tttttttcaa gaaaaaaaat tatataataa ctataatccc ttgctcaccc ctttcccccg   2640

ccaaataaga aacgcaagcc agaccacgat gattgtagaa gtccctcccg ccctggttct   2700

gcacgttaca gttagcagac gagcaattcc atttgttctt ctccagcatc tctaaggccc   2760

acttgaatgc aaaggaaaac acttgcacag caaagcaaga gaagtcacag cagcaagaca   2820

cgcacagtca accattttcc gagaaaaaaa gaaaattccc cacttggaaa gaaagaggag   2880

gaacactgga ttcttacttt ctggatcttg acactgggct gcaaaaccta ccttcctctc   2940

tcccgcctcc cctcaccctc aactctcaat gtcttgctgt cattttctgt ctcggctccc   3000

tcctccccct tcccccttcc cccaccccac acccttcacc ctctgtgtcc tggtccttct   3060

gagggccact gcagatgact ctcctttgaa atgagaaaaa gaaaagaaag caagaacaga   3120

aaacgaagcc acaggaaggg aagtagacat tgtatgctta tggtttctca ttatgaaggt   3180

gcagcttgta ggaggtttgt acggatgtgc tttgaagtta tgtatattac atataacagg   3240

aaaaaatatt aaaataaaca gtgctggtaa gtatgaagct gacattctaa aattataatt   3300

atctgactgt gattgatgta tcctgaggtt cctagatctc actgaactgg cccagctaag   3360

gagacctgga ctctgggtgt gggttggctc acagtagggg ctgacgggtt cagtgtagta   3420

atactgtgtg tggtgtttgt aattggttga ttggtgggga ggggtggggg gccctaatgg   3480

agaggtgtgg gtttggcaag aaagaagcaa cacagatgtc gtccccaaaa tgccagttca   3540

agacaccttc tccctgcccc cctggtagta acagtcaggg cctggtctgt gctcaggtac   3600

tgggtcccag tctgggactc tgctgctgaa gttgccacag tagaggtccc tggcttagtc   3660

cttatctccc tacggggctt gccttggttt tcagtcttct ctctctttct ctcttttttt   3720

tttttttgcc acattctgcc cttccctgac cccattgtaa taaccaactc catatccaaa   3780

gggaggtggt gctctcagcc attgtagaag atggtggctt taacctgact gtctaaaaat   3840

tcccagctaa gccttttcct ctactctctt ccttgttctg aatcatttct tcttctcagg   3900

ccaaagtagc catggtaagg aggcttcatg gggcagaccc tgaaagatca aaactgcatt   3960

tgcaaagccc tcccctgtcc caggacaaag ctgagactga cgggtgatgt tgctcatagg   4020

ctccagctct gcataagacc ttggcttgga gacctccctc tcagtcaaca gctgaactct   4080

gagcttgtgc ccagaaatta ccccaagacc acaggaaccc ttcaagaagc tcccatcaca   4140

agcttggcat tgctctctgc cacacgtggg cttcctcagg cttgtctgcc acaagctact   4200

tctctgagct cagaaagtgc cccttgatga gggaaaatgt cccactgcac tgcgaatttc   4260

tcagttccat tttacctccc agtcctcctt ctaaaccagt taataaattc attccacaag   4320

tatttactga ttacctgctt gtgccaggga ctattctcag gctgaagaag gtgggagggg   4380

agggcggaac ctgaggagcc acctgagcca gctttatatt tcaaccatgg ctggcccatc   4440

tgagagcatc tccccactct cgccaaccta tcggggcata gcccagggat gcccccaggc   4500

ggcccaggtt agatgcgtcc ctttggcttg tcagtgatga catacacctt agctgcttag   4560

ctggtgctgg cctgaggcag ggcaggaaat cagaatagca tttgcttctc tgggcaaatg   4620

ggaagttcag cggggcagca gaatcagtgg cattccccct ggtgcaggcc ggtgggtcca   4680

ctccaactcc ccctgagtgt agcagcacac tttccataca ccaggttctt tctacaatcc   4740

tggtggaaaa gccacagaac cttcttcctg cccttcttga gagttccccc tctttctggg   4800

tcaagagctg gagtggtggc tccatcctct ctgggccact tcggtctagg aactcatctt   4860

tgcaggaacc aggagtcctg agcacactga acacacctca gagggaggat ccttgttgtg   4920

gattttgcac ctggctttgg ggcaggggtg aagtgaccag gcttagcttg tggagtttat   4980

gggccaccag ggtttgggga aatcaccatc ccgcggatgc tgtgacctcc cttctacgga   5040

gatgcaggca gtgccacgag ggaggagggg acctgcaaag ctagaatcta gggcactgtt   5100

tcctccccat ccttctcttt gtagagaata gagacgtttg tcttgtctgt cttcaaccta   5160

cttttccttt tctctttttt gtttctcatc ctctctgtgc cacctctcca cccaggaggc   5220

catgtagcat agtggaaaaa gtccctgagg gcggttagga gttctgggtg accatcctgg   5280

ctcagctcct aactcaccat gtgacatcag gctatcccca ttccccctct tgggcctcag   5340

tttcccgact tgcaaaataa gcagaaagaa ccagatgctc tccagggtct ttttctactt   5400

tgctatctca tgggtcttca ttttctctta ttttgttttc tctggatctt ttccatctga   5460

gggtacagga agtaccagga cctgtttcag tttttgaatc ctgcaagcac attccaagac   5520

tggcctgaaa ctgcatgagc aacatcactc gaaataattt tttttttcaa aagcacctta   5580

acaaccaatt gcgatgctgt cctgttcctt tttactcaca cccttctctc ctttctcgtc   5640

cccatgctcc cccacctcag tgctccgtgc tgtatgcgtg tgctctctgt tcttgtatac   5700

tcaatataag tgaaataaat gtgtttgatg ctgaaccata                         5740


<210>  10076
<211>  700
<212>  PRT
<213>  Homo sapiens

<400>  10076

Met Val Phe Leu Gly Arg Ile Asn Glu Val Glu Pro Ala Lys Gly Leu 
1               5                   10                  15


Ala Glu Ser Leu Ala Pro Thr Glu Arg Ser Val Lys Ser Leu Asp Met 
            20                  25                  30


Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr Thr 
        35                  40                  45


Pro Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr Lys 
    50                  55                  60


Ser Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu Cys 
65                  70                  75                  80


Glu Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val Cys 
                85                  90                  95


Glu His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe Cys 
            100                 105                 110


Asp Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys 
        115                 120                 125


Lys Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe 
    130                 135                 140


Tyr Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr 
145                 150                 155                 160


Leu Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys 
                165                 170                 175


Ser Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu 
            180                 185                 190


Leu Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu 
        195                 200                 205


Leu Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met 
    210                 215                 220


Glu Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile 
225                 230                 235                 240


His Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu 
                245                 250                 255


His His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys 
            260                 265                 270


Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe 
        275                 280                 285


Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr 
    290                 295                 300


Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly 
305                 310                 315                 320


Phe Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys 
                325                 330                 335


Ile Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro 
            340                 345                 350


Lys Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr 
        355                 360                 365


Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro 
    370                 375                 380


Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu 
385                 390                 395                 400


Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp 
                405                 410                 415


Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly 
            420                 425                 430


Gln Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile 
        435                 440                 445


Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His 
    450                 455                 460


Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser 
465                 470                 475                 480


Lys Leu Ile His Arg Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro 
                485                 490                 495


Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn 
            500                 505                 510


Glu Pro Val Lys Thr Glu Thr Met Thr Val Ser Ser Leu Ala Ile Arg 
        515                 520                 525


Lys Lys Ile Glu Pro Glu Ala Val Leu Gln Thr Arg Val Ser Ala Met 
    530                 535                 540


Asp Asn Thr Gln Val Asp Gly Ser Ala Ser Val Gly Arg Glu Phe Ile 
545                 550                 555                 560


Ala Thr Thr Pro Ser Ile Thr Thr Glu Thr Ile Ser Thr Thr Met Glu 
                565                 570                 575


Asn Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro 
            580                 585                 590


Gln Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys 
        595                 600                 605


Asp Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr 
    610                 615                 620


Ser Thr Thr Thr His Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu 
625                 630                 635                 640


Thr Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp 
                645                 650                 655


Gln Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His 
            660                 665                 670


Pro Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro 
        675                 680                 685


Ser Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
    690                 695                 700


<210>  10077
<211>  3861
<212>  DNA
<213>  Homo sapiens

<400>  10077
cgcctcggag cccgccgggg cagccgccgg acaccaggac cgcgagccag acagctcccg     60

gaagccgcgc cgccgccgcc agccacagca cagccggaca gaggaggtgg attaggagtt    120

cccgggaggg agcctgctca gcctttccct gacatttggg caaatgtgtg gggagatgcg    180

gagctcaagg cgtgctggtc accatgacaa cagagacagg ccccgactct gaggtgaaga    240

aagctcagga ggaggccccg cagcagcccg aggctgctgc cgctgtgacc acccctgtga    300

cccctgcagg ccacggccac ccagaggcca actccaatga gaagcatcca tcccagcagg    360

acacgcggcc tgctgaacag agcctagaca tggaggagaa ggactacagt gaggccgatg    420

gcctttcgga gaggaccacg cccagcaagg cccagaaatc gccccagaag attgccaaga    480

aatacaagag tgccatctgc cgggtcactc tgcttgatgc ctcggagtat gagtgtgagg    540

tggagaaaca tggccggggc caggtgctgt ttgacctggt ctgtgaacac ctcaacctcc    600

tagagaagga ctacttcggc ctgaccttct gtgatgctga cagccagaag aactggctgg    660

acccctccaa ggagatcaag aagcagatcc ggagtagccc ctggaatttt gccttcacag    720

tcaagttcta cccgcctgat cctgcccagc tgacagaaga catcacaaga tactacctgt    780

gcctgcagct gcgggcagac atcatcacgg gccggctgcc atgctccttt gtcacgcatg    840

ccctactggg ctcctacgct gtgcaggctg agctgggtga ctatgatgct gaggagcatg    900

tgggcaacta tgtcagcgag ctccgcttcg cccctaacca gacccgggag ctggaggaga    960

ggatcatgga gctgcataag acatataggg ggatgacccc gggagaagca gaaatccact   1020

tcttagagaa tgccaagaag ctttccatgt acggagtaga cctgcaccat gccaaggact   1080

ctgagggcat cgacatcatg ttaggcgttt gtgccaatgg cctgctcatc taccgggacc   1140

ggctgagaat caaccgcttt gcctggccca agatcctcaa gatctcctac aagaggagta   1200

acttctatat caagatccgg cctggggagt atgagcaatt tgagagcaca attggcttta   1260

agctcccaaa ccaccggtca gccaagagac tgtggaaggt ctgcatcgag catcatacat   1320

tcttccggct ggtgtcccct gagcccccac ccaagggctt cctggtgatg ggctccaagt   1380

tccggtacag tgggaggacc caggcacaga ctcgccaggc cagcgccctc attgaccggc   1440

ctgcaccctt ctttgagcgt tcttccagca aacggtacac catgtcccgc agccttgatg   1500

gagcagagtt ctcccgccca gcctcggtca gcgagaacca tgatgcaggg cctgacggtg   1560

acaagcggga tgaggatggc gagtctgggg ggcaacggtc agaggctgag gagggagagg   1620

tcaggactcc aaccaagatc aaggagctaa agccggagca ggaaaccacg ccgagacaca   1680

agcaggagtt cttagacaag ccagaagatg tcttgctgaa gcaccaggcc agcatcaatg   1740

agctcaaaag gaccctgaag gagcccaaca gcaaactcat ccaccgggat cgagactggg   1800

aacgggagcg caggctgccc tcctcccccg cctccccctc ccccaagggc acccctgaga   1860

aagccaatga gagagcaggg ctgagggagg gctccgagga gaaagtcaaa ccaccacgtc   1920

cccgggcccc agagagtgac acaggcgatg aggaccagga ccaggagagg gacacggtgt   1980

tcctgaagga caaccacctg gccattgagc gcaagtgctc cagcatcacg gtcagctcta   2040

cgtctagcct ggaggctgag gtggacttca cggtcattgg tgactaccat ggcagcgcct   2100

tcgaagactt ctcccgcagc ctgcctgagc tcgaccggga caaaagcgac tcggacactg   2160

agggcctgct gttctcccgg gatctcaaca agggggcccc cagccaggat gatgagtctg   2220

ggggcattga ggacagcccg gatcgagggg cctgctccac cccggatatg ccccagtttg   2280

agcccgtgaa aacagaaacc atgactgtca gcagtctggc cattagaaag aagattgagc   2340

cggaggccgt actgcagacc agagtctccg ctatggataa cacccaggtt gatgggagtg   2400

cctcagtggg gagggagttc atagcaacca ctccctccat caccacggag accatatcga   2460

ccaccatgga gaacagtctc aagtccggga agggggcagc tgccatgatc ccaggcccac   2520

agacggtggc cacggaaatc cgttctcttt ctccgatcat cgggaaagat gtcctcacca   2580

gcacctacgg cgccactgcg gaaaccctct caacctccac caccacccat gtcaccaaaa   2640

ctgtgaaagg agggttttct gagacaagga tcgagaagcg aatcatcatt actggggatg   2700

aagatgtcga tcaagaccag gccctggctt tggccatcaa ggaggccaaa ctgcagcatc   2760

ctgatatgct ggtaaccaaa gctgtcgtat acagagaaac agacccatcc ccagaggaga   2820

gggacaagaa gccacaggaa tcctgacctc tgtgaagaga tcctggcatt tctggtccaa   2880

cccaagccag agaaccatta agaaggggcc ttcattctgg attctccgac gcaacactga   2940

cgtcccagct gcgacgtact gtcactgatg agagactggg aagggaaaag catatatata   3000

tagatatata gagatataga tatatataca ggaaacaccg catccttgca ctgctgctgg   3060

ggctggcaga gcagttggct gacagcaaca accgacatct gaacacctac atttcctttg   3120

cagacaaatt gaagaactgg tgggattttt ttcaagaaaa aaaattatat aataactata   3180

atcccttgct cacccctttc ccccgccaaa taagaaacgc aagccagacc acgatgattg   3240

tagaagtccc tcccgccctg gttctgcacg ttacagttag cagacgagca attccatttg   3300

ttcttctcca gcatctctaa ggcccacttg aatgcaaagg aaaacacttg cacagcaaag   3360

caagagaagt cacagcagca agacacgcac agtcaaccat tttccgagaa aaaaagaaaa   3420

ttccccactt ggaaagaaag aggaggaaca ctggattctt actttctgga tcttgacact   3480

gggctgcaaa acctaccttc ctctctcccg cctcccctca ccctcaactc tcaatgtctt   3540

gctgtcattt tctgtctcgg ctccctcctc ccccttcccc cttcccccac cccacaccct   3600

tcaccctctg tgtcctggtc cttctgaggg ccactgcaga tgactctcct ttgaaatgag   3660

aaaaagaaaa gaaagcaaga acagaaaacg aagccacagg aagggaagta gacattgtat   3720

gcttatggtt tctcattatg aaggtgcagc ttgtaggagg tttgtacgga tgtgctttga   3780

agttatgtat attacatata acaggaaaaa atattaaaat aaacagtgct ggtaagtatg   3840

aagctgacat tctaaaatta t                                             3861


<210>  10078
<211>  880
<212>  PRT
<213>  Homo sapiens

<400>  10078

Met Thr Thr Glu Thr Gly Pro Asp Ser Glu Val Lys Lys Ala Gln Glu 
1               5                   10                  15


Glu Ala Pro Gln Gln Pro Glu Ala Ala Ala Ala Val Thr Thr Pro Val 
            20                  25                  30


Thr Pro Ala Gly His Gly His Pro Glu Ala Asn Ser Asn Glu Lys His 
        35                  40                  45


Pro Ser Gln Gln Asp Thr Arg Pro Ala Glu Gln Ser Leu Asp Met Glu 
    50                  55                  60


Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr Thr Pro 
65                  70                  75                  80


Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr Lys Ser 
                85                  90                  95


Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu Cys Glu 
            100                 105                 110


Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val Cys Glu 
        115                 120                 125


His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe Cys Asp 
    130                 135                 140


Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys Lys 
145                 150                 155                 160


Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe Tyr 
                165                 170                 175


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu 
            180                 185                 190


Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys Ser 
        195                 200                 205


Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu Leu 
    210                 215                 220


Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu Leu 
225                 230                 235                 240


Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met Glu 
                245                 250                 255


Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile His 
            260                 265                 270


Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His 
        275                 280                 285


His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys Ala 
    290                 295                 300


Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala 
305                 310                 315                 320


Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr Ile 
                325                 330                 335


Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly Phe 
            340                 345                 350


Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys Ile 
        355                 360                 365


Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro Lys 
    370                 375                 380


Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln 
385                 390                 395                 400


Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro Phe 
                405                 410                 415


Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu Asp 
            420                 425                 430


Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp Ala 
        435                 440                 445


Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly Gln 
    450                 455                 460


Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile Lys 
465                 470                 475                 480


Glu Leu Lys Pro Glu Gln Glu Thr Thr Pro Arg His Lys Gln Glu Phe 
                485                 490                 495


Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His Gln Ala Ser Ile Asn 
            500                 505                 510


Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser Lys Leu Ile His Arg 
        515                 520                 525


Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro Ser Ser Pro Ala Ser 
    530                 535                 540


Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn Glu Arg Ala Gly Leu 
545                 550                 555                 560


Arg Glu Gly Ser Glu Glu Lys Val Lys Pro Pro Arg Pro Arg Ala Pro 
                565                 570                 575


Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp Gln Glu Arg Asp Thr Val 
            580                 585                 590


Phe Leu Lys Asp Asn His Leu Ala Ile Glu Arg Lys Cys Ser Ser Ile 
        595                 600                 605


Thr Val Ser Ser Thr Ser Ser Leu Glu Ala Glu Val Asp Phe Thr Val 
    610                 615                 620


Ile Gly Asp Tyr His Gly Ser Ala Phe Glu Asp Phe Ser Arg Ser Leu 
625                 630                 635                 640


Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser Asp Thr Glu Gly Leu Leu 
                645                 650                 655


Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro Ser Gln Asp Asp Glu Ser 
            660                 665                 670


Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly Ala Cys Ser Thr Pro Asp 
        675                 680                 685


Met Pro Gln Phe Glu Pro Val Lys Thr Glu Thr Met Thr Val Ser Ser 
    690                 695                 700


Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu Ala Val Leu Gln Thr Arg 
705                 710                 715                 720


Val Ser Ala Met Asp Asn Thr Gln Val Asp Gly Ser Ala Ser Val Gly 
                725                 730                 735


Arg Glu Phe Ile Ala Thr Thr Pro Ser Ile Thr Thr Glu Thr Ile Ser 
            740                 745                 750


Thr Thr Met Glu Asn Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met 
        755                 760                 765


Ile Pro Gly Pro Gln Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro 
    770                 775                 780


Ile Ile Gly Lys Asp Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu 
785                 790                 795                 800


Thr Leu Ser Thr Ser Thr Thr Thr His Val Thr Lys Thr Val Lys Gly 
                805                 810                 815


Gly Phe Ser Glu Thr Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp 
            820                 825                 830


Glu Asp Val Asp Gln Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala 
        835                 840                 845


Lys Leu Gln His Pro Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg 
    850                 855                 860


Glu Thr Asp Pro Ser Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
865                 870                 875                 880


<210>  10079
<211>  521
<212>  DNA
<213>  Homo sapiens

<400>  10079
gttagccgca cccgccgtcc ccctccgcgt cccggggacc ccgccgcgtc gggtcccgcg     60

tgtgcgtgtg gggtggccgc cgagggcggc gggctcgatt cccgatcttt gggcactgac    120

aggccggcgg gccggctcca ggagccgcgg gcttcgagac ggggtttcac cgtgttagcc    180

aggatggtct caatctcctg acgtcatgat ccgcctgcct cggcctccca aagtgctggg    240

attacaggtg tgagccactg cacccggccg agttcagggc ttctgatggc aaatgaaaaa    300

ccttggtctg ggtcctcatc ctggccacgc ccttcacttg ctctgtgtgt gaccttgggc    360

aattctcttt gctgaacttg agcctttcat ctgcaaactg agactaatgg tggttgaggg    420

gatggcctga gaaataatcc aactccttgg atattccttt ctgcaagtga tcaggcaaag    480

ataaattcca ttttacagat gaggaagctg aggcctgtga a                        521


<210>  10080
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  10080

Leu Ala Ala Pro Ala Val Pro Leu Arg Val Pro Gly Thr Pro Pro Arg 
1               5                   10                  15


Arg Val Pro Arg Val Arg Val Gly Trp Pro Pro Arg Ala Ala Gly Ser 
            20                  25                  30


Ile Pro Asp Leu Trp Ala Leu Thr Gly Arg Arg Ala Gly Ser Arg Ser 
        35                  40                  45


Arg Gly Leu Arg Asp Gly Val Ser Pro Cys 
    50                  55


<210>  10081
<211>  5886
<212>  DNA
<213>  Homo sapiens

<400>  10081
tctgtctctt ctgcaaccac cctagcttag gccctcatca tatctccgct ggataatcac     60

aacaacctcc taactgatgt tcctgcagct tcccctgccc ctcttccatc ctctaccctg    120

taagccagtg gtttctcttt gctcttacaa taaagagcga atcttctcct tggcctccaa    180

ggtccttcgc tgcctggccc ctgctgccgc ttcaggtgca tatttgttac tttctatttt    240

gctttccgcc ttgtcacaag gcctttttgt ttaacaggtt cagcaacttc cctaaggtgc    300

ctcagagagt caaatgccag cctctcaatt tccagcacat gctgggctca tgaactcctg    360

ttctgaggag ctaacgctgt ttcctccctc taggtgcctg actgacagaa gttcttgccc    420

ccggggagct ggtgtggaca gaggaggggg aggcttcctg ggaaactgga aggcagaagc    480

cacgcagact tctagtcctg gttccactgc ttactcggcg tgctggtcac catgacaaca    540

gagacaggcc ccgactctga ggtgaagaaa gctcaggagg aggccccgca gcagcccgag    600

gctgctgccg ctgtgaccac ccctgtgacc cctgcaggcc acggccaccc agaggccaac    660

tccaatgaga agcatccatc ccagcaggac acgcggcctg ctgaacagag cctagacatg    720

gaggagaagg actacagtga ggccgatggc ctttcggaga ggaccacgcc cagcaaggcc    780

cagaaatcgc cccagaagat tgccaagaaa tacaagagtg ccatctgccg ggtcactctg    840

cttgatgcct cggagtatga gtgtgaggtg gagaaacatg gccggggcca ggtgctgttt    900

gacctggtct gtgaacacct caacctccta gagaaggact acttcggcct gaccttctgt    960

gatgctgaca gccagaagaa ctggctggac ccctccaagg agatcaagaa gcagatccgg   1020

agtagcccct ggaattttgc cttcacagtc aagttctacc cgcctgatcc tgcccagctg   1080

acagaagaca tcacaagggg gatgaccccg ggagaagcag aaatccactt cttagagaat   1140

gccaagaagc tttccatgta cggagtagac ctgcaccatg ccaaggactc tgagggcatc   1200

gacatcatgt taggcgtttg tgccaatggc ctgctcatct accgggaccg gctgagaatc   1260

aaccgctttg cctggcccaa gatcctcaag atctcctaca agaggagtaa cttctatatc   1320

aagatccggc ctggggagta tgagcaattt gagagcacaa ttggctttaa gctcccaaac   1380

caccggtcag ccaagagact gtggaaggtc tgcatcgagc atcatacatt cttccggctg   1440

gtgtcccctg agcccccacc caagggcttc ctggtgatgg gctccaagtt ccggtacagt   1500

gggaggaccc aggcacagac tcgccaggcc agcgccctca ttgaccggcc tgcacccttc   1560

tttgagcgtt cttccagcaa acggtacacc atgtcccgca gccttgatgg agcagagttc   1620

tcccgcccag cctcggtcag cgagaaccat gatgcagggc ctgacggtga caagcgggat   1680

gaggatggcg agtctggggg gcaacggtca gaggctgagg agggagaggt caggactcca   1740

accaagatca aggagctaaa gttcttagac aagccagaag atgtcttgct gaagcaccag   1800

gccagcatca atgagctcaa aaggaccctg aaggagccca acagcaaact catccaccgg   1860

gatcgagact gggaacggga gcgcaggctg ccctcctccc ccgcctcccc ctcccccaag   1920

ggcacccctg agaaagccaa tgagcccgtg aaaacagaaa ccatgactgt cagcagtctg   1980

gccattagaa agaagattga gccggaggcc gtactgcaga ccagagtctc cgctatggat   2040

aacacccagg agaacagtct caagtccggg aagggggcag ctgccatgat cccaggccca   2100

cagacggtgg ccacggaaat ccgttctctt tctccgatca tcgggaaaga tgtcctcacc   2160

agcacctacg gcgccactgc ggaaaccctc tcaacctcca ccaccaccca tgtcaccaaa   2220

actgtgaaag gagggttttc tgagacaagg atcgagaagc gaatcatcat tactggggat   2280

gaagatgtcg atcaagacca ggccctggct ttggccatca aggaggccaa actgcagcat   2340

cctgatatgc tggtaaccaa agctgtcgta tacagagaaa cagacccatc cccagaggag   2400

agggacaaga agccacagga atcctgacct ctgtgaagag atcctggcat ttctggtcca   2460

acccaagcca gagaaccatt aagaaggggc cttcattctg gattctccga cgcaacactg   2520

acgtcccagc tgcgacgtac tgtcactgat gagagactgg gaagggaaaa gcatatatat   2580

atagatatat agagatatag atatatatac aggaaacacc gcatccttgc actgctgctg   2640

gggctggcag agcagttggc tgacagcaac aaccgacatc tgaacaccta catttccttt   2700

gcagacaaat tgaagaactg gtgggatttt tttcaagaaa aaaaattata taataactat   2760

aatcccttgc tcaccccttt cccccgccaa ataagaaacg caagccagac cacgatgatt   2820

gtagaagtcc ctcccgccct ggttctgcac gttacagtta gcagacgagc aattccattt   2880

gttcttctcc agcatctcta aggcccactt gaatgcaaag gaaaacactt gcacagcaaa   2940

gcaagagaag tcacagcagc aagacacgca cagtcaacca ttttccgaga aaaaaagaaa   3000

attccccact tggaaagaaa gaggaggaac actggattct tactttctgg atcttgacac   3060

tgggctgcaa aacctacctt cctctctccc gcctcccctc accctcaact ctcaatgtct   3120

tgctgtcatt ttctgtctcg gctccctcct cccccttccc ccttccccca ccccacaccc   3180

ttcaccctct gtgtcctggt ccttctgagg gccactgcag atgactctcc tttgaaatga   3240

gaaaaagaaa agaaagcaag aacagaaaac gaagccacag gaagggaagt agacattgta   3300

tgcttatggt ttctcattat gaaggtgcag cttgtaggag gtttgtacgg atgtgctttg   3360

aagttatgta tattacatat aacaggaaaa aatattaaaa taaacagtgc tggtaagtat   3420

gaagctgaca ttctaaaatt ataattatct gactgtgatt gatgtatcct gaggttccta   3480

gatctcactg aactggccca gctaaggaga cctggactct gggtgtgggt tggctcacag   3540

taggggctga cgggttcagt gtagtaatac tgtgtgtggt gtttgtaatt ggttgattgg   3600

tggggagggg tggggggccc taatggagag gtgtgggttt ggcaagaaag aagcaacaca   3660

gatgtcgtcc ccaaaatgcc agttcaagac accttctccc tgcccccctg gtagtaacag   3720

tcagggcctg gtctgtgctc aggtactggg tcccagtctg ggactctgct gctgaagttg   3780

ccacagtaga ggtccctggc ttagtcctta tctccctacg gggcttgcct tggttttcag   3840

tcttctctct ctttctctct tttttttttt tttgccacat tctgcccttc cctgacccca   3900

ttgtaataac caactccata tccaaaggga ggtggtgctc tcagccattg tagaagatgg   3960

tggctttaac ctgactgtct aaaaattccc agctaagcct tttcctctac tctcttcctt   4020

gttctgaatc atttcttctt ctcaggccaa agtagccatg gtaaggaggc ttcatggggc   4080

agaccctgaa agatcaaaac tgcatttgca aagccctccc ctgtcccagg acaaagctga   4140

gactgacggg tgatgttgct cataggctcc agctctgcat aagaccttgg cttggagacc   4200

tccctctcag tcaacagctg aactctgagc ttgtgcccag aaattacccc aagaccacag   4260

gaacccttca agaagctccc atcacaagct tggcattgct ctctgccaca cgtgggcttc   4320

ctcaggcttg tctgccacaa gctacttctc tgagctcaga aagtgcccct tgatgaggga   4380

aaatgtccca ctgcactgcg aatttctcag ttccatttta cctcccagtc ctccttctaa   4440

accagttaat aaattcattc cacaagtatt tactgattac ctgcttgtgc cagggactat   4500

tctcaggctg aagaaggtgg gaggggaggg cggaacctga ggagccacct gagccagctt   4560

tatatttcaa ccatggctgg cccatctgag agcatctccc cactctcgcc aacctatcgg   4620

ggcatagccc agggatgccc ccaggcggcc caggttagat gcgtcccttt ggcttgtcag   4680

tgatgacata caccttagct gcttagctgg tgctggcctg aggcagggca ggaaatcaga   4740

atagcatttg cttctctggg caaatgggaa gttcagcggg gcagcagaat cagtggcatt   4800

ccccctggtg caggccggtg ggtccactcc aactccccct gagtgtagca gcacactttc   4860

catacaccag gttctttcta caatcctggt ggaaaagcca cagaaccttc ttcctgccct   4920

tcttgagagt tccccctctt tctgggtcaa gagctggagt ggtggctcca tcctctctgg   4980

gccacttcgg tctaggaact catctttgca ggaaccagga gtcctgagca cactgaacac   5040

acctcagagg gaggatcctt gttgtggatt ttgcacctgg ctttggggca ggggtgaagt   5100

gaccaggctt agcttgtgga gtttatgggc caccagggtt tggggaaatc accatcccgc   5160

ggatgctgtg acctcccttc tacggagatg caggcagtgc cacgagggag gaggggacct   5220

gcaaagctag aatctagggc actgtttcct ccccatcctt ctctttgtag agaatagaga   5280

cgtttgtctt gtctgtcttc aacctacttt tccttttctc ttttttgttt ctcatcctct   5340

ctgtgccacc tctccaccca ggaggccatg tagcatagtg gaaaaagtcc ctgagggcgg   5400

ttaggagttc tgggtgacca tcctggctca gctcctaact caccatgtga catcaggcta   5460

tccccattcc ccctcttggg cctcagtttc ccgacttgca aaataagcag aaagaaccag   5520

atgctctcca gggtcttttt ctactttgct atctcatggg tcttcatttt ctcttatttt   5580

gttttctctg gatcttttcc atctgagggt acaggaagta ccaggacctg tttcagtttt   5640

tgaatcctgc aagcacattc caagactggc ctgaaactgc atgagcaaca tcactcgaaa   5700

taattttttt tttcaaaagc accttaacaa ccaattgcga tgctgtcctg ttccttttta   5760

ctcacaccct tctctccttt ctcgtcccca tgctccccca cctcagtgct ccgtgctgta   5820

tgcgtgtgct ctctgttctt gtatactcaa tataagtgaa ataaatgtgt ttgatgctga   5880

accata                                                              5886


<210>  10082
<211>  631
<212>  PRT
<213>  Homo sapiens

<400>  10082

Met Thr Thr Glu Thr Gly Pro Asp Ser Glu Val Lys Lys Ala Gln Glu 
1               5                   10                  15


Glu Ala Pro Gln Gln Pro Glu Ala Ala Ala Ala Val Thr Thr Pro Val 
            20                  25                  30


Thr Pro Ala Gly His Gly His Pro Glu Ala Asn Ser Asn Glu Lys His 
        35                  40                  45


Pro Ser Gln Gln Asp Thr Arg Pro Ala Glu Gln Ser Leu Asp Met Glu 
    50                  55                  60


Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr Thr Pro 
65                  70                  75                  80


Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr Lys Ser 
                85                  90                  95


Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu Cys Glu 
            100                 105                 110


Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val Cys Glu 
        115                 120                 125


His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe Cys Asp 
    130                 135                 140


Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys Lys 
145                 150                 155                 160


Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe Tyr 
                165                 170                 175


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Gly Met Thr 
            180                 185                 190


Pro Gly Glu Ala Glu Ile His Phe Leu Glu Asn Ala Lys Lys Leu Ser 
        195                 200                 205


Met Tyr Gly Val Asp Leu His His Ala Lys Asp Ser Glu Gly Ile Asp 
    210                 215                 220


Ile Met Leu Gly Val Cys Ala Asn Gly Leu Leu Ile Tyr Arg Asp Arg 
225                 230                 235                 240


Leu Arg Ile Asn Arg Phe Ala Trp Pro Lys Ile Leu Lys Ile Ser Tyr 
                245                 250                 255


Lys Arg Ser Asn Phe Tyr Ile Lys Ile Arg Pro Gly Glu Tyr Glu Gln 
            260                 265                 270


Phe Glu Ser Thr Ile Gly Phe Lys Leu Pro Asn His Arg Ser Ala Lys 
        275                 280                 285


Arg Leu Trp Lys Val Cys Ile Glu His His Thr Phe Phe Arg Leu Val 
    290                 295                 300


Ser Pro Glu Pro Pro Pro Lys Gly Phe Leu Val Met Gly Ser Lys Phe 
305                 310                 315                 320


Arg Tyr Ser Gly Arg Thr Gln Ala Gln Thr Arg Gln Ala Ser Ala Leu 
                325                 330                 335


Ile Asp Arg Pro Ala Pro Phe Phe Glu Arg Ser Ser Ser Lys Arg Tyr 
            340                 345                 350


Thr Met Ser Arg Ser Leu Asp Gly Ala Glu Phe Ser Arg Pro Ala Ser 
        355                 360                 365


Val Ser Glu Asn His Asp Ala Gly Pro Asp Gly Asp Lys Arg Asp Glu 
    370                 375                 380


Asp Gly Glu Ser Gly Gly Gln Arg Ser Glu Ala Glu Glu Gly Glu Val 
385                 390                 395                 400


Arg Thr Pro Thr Lys Ile Lys Glu Leu Lys Phe Leu Asp Lys Pro Glu 
                405                 410                 415


Asp Val Leu Leu Lys His Gln Ala Ser Ile Asn Glu Leu Lys Arg Thr 
            420                 425                 430


Leu Lys Glu Pro Asn Ser Lys Leu Ile His Arg Asp Arg Asp Trp Glu 
        435                 440                 445


Arg Glu Arg Arg Leu Pro Ser Ser Pro Ala Ser Pro Ser Pro Lys Gly 
    450                 455                 460


Thr Pro Glu Lys Ala Asn Glu Pro Val Lys Thr Glu Thr Met Thr Val 
465                 470                 475                 480


Ser Ser Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu Ala Val Leu Gln 
                485                 490                 495


Thr Arg Val Ser Ala Met Asp Asn Thr Gln Glu Asn Ser Leu Lys Ser 
            500                 505                 510


Gly Lys Gly Ala Ala Ala Met Ile Pro Gly Pro Gln Thr Val Ala Thr 
        515                 520                 525


Glu Ile Arg Ser Leu Ser Pro Ile Ile Gly Lys Asp Val Leu Thr Ser 
    530                 535                 540


Thr Tyr Gly Ala Thr Ala Glu Thr Leu Ser Thr Ser Thr Thr Thr His 
545                 550                 555                 560


Val Thr Lys Thr Val Lys Gly Gly Phe Ser Glu Thr Arg Ile Glu Lys 
                565                 570                 575


Arg Ile Ile Ile Thr Gly Asp Glu Asp Val Asp Gln Asp Gln Ala Leu 
            580                 585                 590


Ala Leu Ala Ile Lys Glu Ala Lys Leu Gln His Pro Asp Met Leu Val 
        595                 600                 605


Thr Lys Ala Val Val Tyr Arg Glu Thr Asp Pro Ser Pro Glu Glu Arg 
    610                 615                 620


Asp Lys Lys Pro Gln Glu Ser 
625                 630


<210>  10083
<211>  625
<212>  DNA
<213>  Homo sapiens

<400>  10083
tttccagcac atgctgggct catgaactcc tgttctgagg agctaacgct gtttcctccc     60

tctaggtgcc tgactgacag aagttcttgc ccccggggag ctggtgtgga cagaggaggg    120

gccctggaag tgaccactgg gctgagtagc tcatcagctt ccccacactg aagcccgagg    180

ggtctcctgc tggcttctga gagctgacgg aacaggttcc agcaaggcag accctgacac    240

agaagccaga cctgtccagc agggacccca tacactggga ggcttcctgg gaaactggaa    300

ggcagaagcc acgcagactt ctagtcctgg ttccactgct tactcggctg ctgttcgtac    360

ctgcctcatg gttttcttgg ggaggatcaa tgaggtagaa cctgcaaagg gcttagcaga    420

gagcctagca cctactgagc gctcagtaaa ggcgtgctgg tcaccatgac aacagagaca    480

ggccccgact ctgaggtgaa gaaagctcag gaggaggccc cgcagcagcc cgaggctgct    540

gccgctgtga ccacccctgt gacccctgca ggccacggcc acccagaggc caactccaat    600

gagaagcatc catcccagca ggaca                                          625


<210>  10084
<211>  49
<212>  PRT
<213>  Homo sapiens

<400>  10084

Met Asn Ser Cys Ser Glu Glu Leu Thr Leu Phe Pro Pro Ser Arg Cys 
1               5                   10                  15


Leu Thr Asp Arg Ser Ser Cys Pro Arg Gly Ala Gly Val Asp Arg Gly 
            20                  25                  30


Gly Ala Leu Glu Val Thr Thr Gly Leu Ser Ser Ser Ser Ala Ser Pro 
        35                  40                  45


His 



<210>  10085
<211>  534
<212>  DNA
<213>  Homo sapiens

<400>  10085
aacatcccat ccctgcctcc caccacacct gtgacagaca gtggccaggt ctggctgctg     60

cctctagacc ccagaggtgg agagaggcta ggtcacaaag ctaaaaacta aaccaggctc    120

tgaaggccaa ctaagaagtc ctctctgacc ctcaacctga aatgctggaa ttccttcaag    180

aaggattgga gaaatccagg gactccagag actgtaagag tcacagaaga aatactggat    240

gtctggacct tacgtgggca acattcctga ggcctgagtc ccccagagac acccctccag    300

ctctcaggca ggcagcaatc caggacgaat gatctgctac catgtagaag agaggatgga    360

gagcagctag ggtagccaga gtcagcattt cagagccact gccacaggag gaggaattgg    420

tgggcaagag caggggaggg aaggggcagt tttccatgtt gagtctccac acttatgtcc    480

ctccttcagc agacaatggc acagccattc atatttcatg tgacaactgc attt          534


<210>  10086
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  10086

Met Leu Glu Phe Leu Gln Glu Gly Leu Glu Lys Ser Arg Asp Ser Arg 
1               5                   10                  15


Asp Cys Lys Ser His Arg Arg Asn Thr Gly Cys Leu Asp Leu Thr Trp 
            20                  25                  30


Ala Thr Phe Leu Arg Pro Glu Ser Pro Arg Asp Thr Pro Pro Ala Leu 
        35                  40                  45


Arg Gln Ala Ala Ile Gln Asp Glu 
    50                  55


<210>  10087
<211>  1753
<212>  DNA
<213>  Homo sapiens

<400>  10087
atggtacgta acaaatgatc caatttctac aaaatacgtt ttttgttctt ttttcttttc     60

tttttttttt tttttgagat ggagtttttg ctctattgcc caggctgaag tgcagtggca    120

tgatctcggc tcactgcaac ctccgcctcc tgggttcaag caattctccc acctcagcct    180

cccgagtaat tgggattaca ggtgccccgc caccacgcct ggttaatttt tgtattttta    240

gaagagacag ggtttcacca tgttggccag gctggtctcg aactcctgac ctcaagtgat    300

ctgtccacgt cagcactttg ggaggccaag gtggttggat cacttgaggc caggagttca    360

agaccagcac ggccaacatg gcgaaacctc atccctacta aaaaaaaaaa aaaaaaaaca    420

tacaaaaagt agccaggtgt ggtggcgcgc acctgtagtc cctgctactc aggaggctga    480

ggcacaagaa tcacttgaat ctgggaagca gaggttgcag tgagcagaga ttgcgcttct    540

gcactccagc ctgggtgaca gagcgagact ctgtctcaaa aacaaacaaa caaacaacaa    600

caacaaaaaa aaaccaccta ggccgggcac ggtggctcat gcctgcaatc ccagcacttt    660

gggaggccaa ggtgggcgga tcacctgagg tcgggagttc gagaccagct gaccaacatg    720

gagaaactcc atctctacta aaaatacaaa attagccagg catggtggca catgcctgta    780

atctcagcta ctcaggaggt tgaggcaaga gaatcgcttg aacccaggag gcagaggttg    840

cggtgagccc agatcgtacc attgcactcc agcctgggca acaagagtga aactccgtct    900

taaaaaaaat aaataaataa taataagaag aaagcactta atcctatccc tttactgcac    960

agatggggaa actgagaccc agagagggga agggctttgt aatcagtcag catctattta   1020

tttactgagc aacaactagg tctgaagcgc tgagctagtg ctgtgaatga ggaaaaattt   1080

aaacttctgt gttattggat agacaagctg tgactctatg tattaatcat tgctaaacct   1140

aggcaatggg ttcacagaag tgcattacac tatactcttt atttttatgt atgtttgaaa   1200

ttttgcataa caaaaaaatt ttttttaaag gatgacagaa agataactga ctatcatgca   1260

aaccgtaagt ctggcttgaa cttataaaac tcgaaacaaa tttaggaata tttttgctct   1320

gatagttttg aaaatcagaa aaaggcaatt gtactggaat ctacttcata gcctttcttt   1380

tcccaccttt ctgtaaaatt ttctgcctct gttgttgcta ggaaatcagt gagccaagag   1440

aatcctcgtt ggcctagccg ggccgtctcc cttcccacac tgcctctctg ggggtacagc   1500

gtccctgtac ccaggaagct ggccctcttg ggccggcttt ctgtggatcc acaaggcaat   1560

caccacaaga ggctgaataa gagcctgtca gtcactggga gacaggcagc tataaatcca   1620

gaggaccatg attagaaagc aaattacagg cctcccgctc taagtttcca actcacaaaa   1680

cttcttggca gtcaaagggc ctttacttaa gttgttcaaa gtttccagag agagtgaaca   1740

cacacaaggc aag                                                      1753


<210>  10088
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  10088

Met Ile Ser Ala His Cys Asn Leu Arg Leu Leu Gly Ser Ser Asn Ser 
1               5                   10                  15


Pro Thr Ser Ala Ser Arg Val Ile Gly Ile Thr Gly Ala Pro Pro Pro 
            20                  25                  30


Arg Leu Val Asn Phe Cys Ile Phe Arg Arg Asp Arg Val Ser Pro Cys 
        35                  40                  45


Trp Pro Gly Trp Ser Arg Thr Pro Asp Leu Lys 
    50                  55


<210>  10089
<211>  478
<212>  DNA
<213>  Homo sapiens

<400>  10089
accaatgcat cctcagagct ccgagggaaa agcaacgacg atggctggca gctgagggag     60

agaccagcat ccccagaact cccttttggt ccttgtccag acttcaaggt ctccatggac    120

cactttgagc catatacgtc tgccagtcag tggcctctgc acccacgtca gaagcagcag    180

aaatccaaag agcccttggc ctctggaggc ggcagcagga gtgctctccg aaaagagact    240

gggccagccg gtgggagccc agcgcccacc caccgctcat cctacagcag gaccaacccc    300

ccgccaaccc ccagcctccg gatcctctct ccaggccttg gaggaggctg cagaccggtt    360

tagatactct ggggtcctaa ctcagcccat agggatcaga aaaggcttcc tggaggagaa    420

gacactaagc caagctgggt taaagccaag ccccctgtac atgtctgggc atcccaga      478


<210>  10090
<211>  82
<212>  PRT
<213>  Homo sapiens

<400>  10090

Met Asp His Phe Glu Pro Tyr Thr Ser Ala Ser Gln Trp Pro Leu His 
1               5                   10                  15


Pro Arg Gln Lys Gln Gln Lys Ser Lys Glu Pro Leu Ala Ser Gly Gly 
            20                  25                  30


Gly Ser Arg Ser Ala Leu Arg Lys Glu Thr Gly Pro Ala Gly Gly Ser 
        35                  40                  45


Pro Ala Pro Thr His Arg Ser Ser Tyr Ser Arg Thr Asn Pro Pro Pro 
    50                  55                  60


Thr Pro Ser Leu Arg Ile Leu Ser Pro Gly Leu Gly Gly Gly Cys Arg 
65                  70                  75                  80


Pro Val 



<210>  10091
<211>  2887
<212>  DNA
<213>  Homo sapiens

<400>  10091
atgcctagcc cttggcagag tcctgtctat agcacaacca ccgcagcagg gaagccagca     60

cctgagctgc aagagcccca gaacaagagg tggaagacct ggaggaggtg ctatgcggat    120

ccagaagtga atgtgggaac acgtggtgct ctctccccca ccaatgcatc ctcagagctc    180

cgagggaaaa gcaacgacga tggctggcag ctgagggaga gaccagcatc cccagaactc    240

ccttttggtc cttgtccaga cttcaaggtc tccatggacc actttgagcc atatacgtct    300

gccagtcagt ggcctctgca cccacgtcag aagcagcaga aatccaaaga gcccttggcc    360

tctggaggcg gcagcaggag tgctctccga aaagagactg ggccagccgg tgggagccca    420

gcgcccaccc accgctcatc ctacagcagg accaaccccc cgccaacccc cagcctccgg    480

atcctctctc caggccttgg aggaggctgc agaccggtgt ctttagacaa agcttccggt    540

gccttcactc cccctgctca ccaggttcag cagcggatga agagcagaga gcagaatgaa    600

gccagcttct cccagtccta gagaacaggc ccaccctcca gacagaagat gcacagctgc    660

taagagattc ttgactgcct gccttcaagt attttgattc caaataggct cagtctcccc    720

tgctggctga gccttcccaa tcgtgggctc ccgtgggcag gaggctctgg gctgcatggc    780

caaggctctc tctgttcctc ttagttcaac tctccttccc tggccatctc cctttccttc    840

cttcccccag gctgaagccc tccccactcc tcccctgggg cagggccact ttcccaccct    900

cctcaaccag atggagcctc tcactttccc aggagaatcc aggctacact ccaaagaccg    960

aggcaggatg ttcccagaca tcgttctgca tttataccca aagggctcaa ttcacttcag   1020

gtcattgaga ccacacagaa aatgaggctt ctgctatttt aattattttg attattatta   1080

ttattcacta acatttctat tagcactttc cagtttgcaa aatacttttg tgtgtcatct   1140

gcacagcatc ttgtgagata atatcatccc tcatcttttt ttttttcttt tttgagacgg   1200

agtctcgctc tgttgcccag gctggagtgc agtggcgcga tctcggctca ctgcaagctc   1260

cgcctctcgg gttcacgcca ttctcctgcc tcagcctccc gagtagctgg gactacaggc   1320

gcctgccacc accatgccca gctaattttt ttttgcattt ttagtagaga tggggtttca   1380

ccatgttagc caggatggtc tcgatctcct gacctcgtga tccgcccgcc tcggcctccc   1440

aaagtgctgg gattacaggc gtgagccacc gcgcccggcc cccatcttat aaataggcag   1500

gctgaggctc agagtgggag tgacttgccc aaggttacgc ttacacagtt acactggctc   1560

cctggactac atactttcca ctttacccaa caataaccct ttccagaaaa atcaggctgg   1620

aggaagcagg agagacactt aagaatgtat ggcccccata ggcatcagtt gcaattacta   1680

cttgagttac ttgactgttt tcattcccca ggcagggaaa ctgaggcaca gggataggac   1740

tcaacctagg accaagtctc atggagaaag aaggaaagag gagcccatcc aaaaaagggg   1800

ttcctcagtt ccttagctgc aaattctgct tccagcccta gcgctaccat ttctttttgt   1860

attacttagg caggttattt gacatctctg agcctcaatt ttctcaccta taaaatggga   1920

gaatccctgc cccatgtctg tcactgggct gctgtgatgg gaggtcagca gatgctggca   1980

gaagagaagg gacaggaccc ttcattccct ctctgctctg tctaggaggc aggagaaatt   2040

ctttcctctt aaattttaac tggatggaac ttaatggtgc aaaagtccag gatacaggaa   2100

agccaggagg agaacggaag tgattcgctc cactggctgg gaaagcaagg gacacagagt   2160

cagccacaga cccccaaggt cactgcgggg cagagattca accaaacact tcaggcaggg   2220

cccctcctat ctccctttta tctttcaaag gaggaaacca aggttctaag caaagcagtg   2280

acttgccaag gtcacccaca agtagtcagt ggtctcctga ctcccagcca ccagggccct   2340

tgactactgg gcaagcaggg tggggtgggg agcactccca gcccaaggac ttaatctttc   2400

attcagcaag cagtaatgct cacaccaagc caggccctgg acactgggga aggctggagg   2460

aattgaatac agcctctgcc cttgaattca caatcaatct agtggaggca cgtaccccag   2520

cacatcagag gatactagaa ggtgaagcac caccattttc tgagcacttc ctctgtgcct   2580

ggcactggac acacattcat ttgtttaatc ctcaaagcaa ttctctggca ctgaaattat   2640

taatcccttt cacagctgaa gtaactgagg ctcagaaggg ttagcgaccc caaagttcat   2700

ccagctaata aatggcaggg tcggaatatg actgacaggt atgtctggtg ccaaactctg   2760

agcttcaacc cttataaact ccctgttttt aggtctgtgc taaccaatat ggtagctact   2820

agccatggct agttgctatg gagcacttga aatgtggctc gttcaaataa aaatgtgctg   2880

taaatat                                                             2887


<210>  10092
<211>  206
<212>  PRT
<213>  Homo sapiens

<400>  10092

Met Pro Ser Pro Trp Gln Ser Pro Val Tyr Ser Thr Thr Thr Ala Ala 
1               5                   10                  15


Gly Lys Pro Ala Pro Glu Leu Gln Glu Pro Gln Asn Lys Arg Trp Lys 
            20                  25                  30


Thr Trp Arg Arg Cys Tyr Ala Asp Pro Glu Val Asn Val Gly Thr Arg 
        35                  40                  45


Gly Ala Leu Ser Pro Thr Asn Ala Ser Ser Glu Leu Arg Gly Lys Ser 
    50                  55                  60


Asn Asp Asp Gly Trp Gln Leu Arg Glu Arg Pro Ala Ser Pro Glu Leu 
65                  70                  75                  80


Pro Phe Gly Pro Cys Pro Asp Phe Lys Val Ser Met Asp His Phe Glu 
                85                  90                  95


Pro Tyr Thr Ser Ala Ser Gln Trp Pro Leu His Pro Arg Gln Lys Gln 
            100                 105                 110


Gln Lys Ser Lys Glu Pro Leu Ala Ser Gly Gly Gly Ser Arg Ser Ala 
        115                 120                 125


Leu Arg Lys Glu Thr Gly Pro Ala Gly Gly Ser Pro Ala Pro Thr His 
    130                 135                 140


Arg Ser Ser Tyr Ser Arg Thr Asn Pro Pro Pro Thr Pro Ser Leu Arg 
145                 150                 155                 160


Ile Leu Ser Pro Gly Leu Gly Gly Gly Cys Arg Pro Val Ser Leu Asp 
                165                 170                 175


Lys Ala Ser Gly Ala Phe Thr Pro Pro Ala His Gln Val Gln Gln Arg 
            180                 185                 190


Met Lys Ser Arg Glu Gln Asn Glu Ala Ser Phe Ser Gln Ser 
        195                 200                 205


<210>  10093
<211>  6273
<212>  DNA
<213>  Homo sapiens

<400>  10093
agtcggcatc catcagcggg cgggggtgtc gccgaacagg ctgctccgca gagcccgccg     60

cgaccccgcg ccgccccgcc ccgcggcctg cctgccagag gagccgaggg ggccgcccct    120

cgcccaacct gcccgacatg gggaaccccg ggcccaggcg tgctggtcac catgacaaca    180

gagacaggcc ccgactctga ggtgaagaaa gctcaggagg aggccccgca gcagcccgag    240

gctgctgccg ctgtgaccac ccctgtgacc cctgcaggcc acggccaccc agaggccaac    300

tccaatgaga agcatccatc ccagcaggac acgcggcctg ctgaacagag cctagacatg    360

gaggagaagg actacagtga ggccgatggc ctttcggaga ggaccacgcc cagcaaggcc    420

cagaaatcgc cccagaagat tgccaagaaa tacaagagtg ccatctgccg ggtcactctg    480

cttgatgcct cggagtatga gtgtgaggtg gagaaacatg gccggggcca ggtgctgttt    540

gacctggtct gtgaacacct caacctccta gagaaggact acttcggcct gaccttctgt    600

gatgctgaca gccagaagaa ctggctggac ccctccaagg agatcaagaa gcagatccgg    660

agtagcccct ggaattttgc cttcacagtc aagttctacc cgcctgatcc tgcccagctg    720

acagaagaca tcacaagata ctacctgtgc ctgcagctgc gggcagacat catcacgggc    780

cggctgccat gctcctttgt cacgcatgcc ctactgggct cctacgctgt gcaggctgag    840

ctgggtgact atgatgctga ggagcatgtg ggcaactatg tcagcgagct ccgcttcgcc    900

cctaaccaga cccgggagct ggaggagagg atcatggagc tgcataagac atataggggg    960

atgaccccgg gagaagcaga aatccacttc ttagagaatg ccaagaagct ttccatgtac   1020

ggagtagacc tgcaccatgc caaggactct gagggcatcg acatcatgtt aggcgtttgt   1080

gccaatggcc tgctcatcta ccgggaccgg ctgagaatca accgctttgc ctggcccaag   1140

atcctcaaga tctcctacaa gaggagtaac ttctatatca agatccggcc tggggagtat   1200

gagcaatttg agagcacaat tggctttaag ctcccaaacc accggtcagc caagagactg   1260

tggaaggtct gcatcgagca tcatacattc ttccggctgg tgtcccctga gcccccaccc   1320

aagggcttcc tggtgatggg ctccaagttc cggtacagtg ggaggaccca ggcacagact   1380

cgccaggcca gcgccctcat tgaccggcct gcacccttct ttgagcgttc ttccagcaaa   1440

cggtacacca tgtcccgcag ccttgatgga gcagagttct cccgcccagc ctcggtcagc   1500

gagaaccatg atgcagggcc tgacggtgac aagcgggatg aggatggcga gtctgggggg   1560

caacggtcag aggctgagga gggagaggtc aggactccaa ccaagatcaa ggagctaaag   1620

ccggagcagg aaaccacgcc gagacacaag caggagttct tagacaagcc agaagatgtc   1680

ttgctgaagc accaggccag catcaatgag ctcaaaagga ccctgaagga gcccaacagc   1740

aaactcatcc accgggatcg agactgggaa cgggagcgca ggctgccctc ctcccccgcc   1800

tccccctccc ccaagggcac ccctgagaaa gccaatgaga gagcagggct gagggagggc   1860

tccgaggaga aagtcaaacc accacgtccc cgggccccag agagtgacac aggcgatgag   1920

gaccaggacc aggagaggga cacggtgttc ctgaaggaca accacctggc cattgagcgc   1980

aagtgctcca gcatcacggt cagctctacg tctagcctgg aggctgaggt ggacttcacg   2040

gtcattggtg actaccatgg cagcgccttc gaagacttct cccgcagcct gcctgagctc   2100

gaccgggaca aaagcgactc ggacactgag ggcctgctgt tctcccggga tctcaacaag   2160

ggggccccca gccaggatga tgagtctggg ggcattgagg acagcccgga tcgaggggcc   2220

tgctccaccc cggatatgcc ccagtttgag cccgtgaaaa cagaaaccat gactgtcagc   2280

agtctggcca ttagaaagaa gattgagccg gaggccgtac tgcagaccag agtctccgct   2340

atggataaca cccaggttga tgggagtgcc tcagtgggga gggagttcat agcaaccact   2400

ccctccatca ccacggagac catatcgacc accatggaga acagtctcaa gtccgggaag   2460

ggggcagctg ccatgatccc aggcccacag acggtggcca cggaaatccg ttctctttct   2520

ccgatcatcg ggaaagatgt cctcaccagc acctacggcg ccactgcgga aaccctctca   2580

acctccacca ccacccatgt caccaaaact gtgaaaggag ggttttctga gacaaggatc   2640

gagaagcgaa tcatcattac tggggatgaa gatgtcgatc aagaccaggc cctggctttg   2700

gccatcaagg aggccaaact gcagcatcct gatatgctgg taaccaaagc tgtcgtatac   2760

agagaaacag acccatcccc agaggagagg gacaagaagc cacaggaatc ctgacctctg   2820

tgaagagatc ctggcatttc tggtccaacc caagccagag aaccattaag aaggggcctt   2880

cattctggat tctccgacgc aacactgacg tcccagctgc gacgtactgt cactgatgag   2940

agactgggaa gggaaaagca tatatatata gatatataga gatatagata tatatacagg   3000

aaacaccgca tccttgcact gctgctgggg ctggcagagc agttggctga cagcaacaac   3060

cgacatctga acacctacat ttcctttgca gacaaattga agaactggtg ggattttttt   3120

caagaaaaaa aattatataa taactataat cccttgctca cccctttccc ccgccaaata   3180

agaaacgcaa gccagaccac gatgattgta gaagtccctc ccgccctggt tctgcacgtt   3240

acagttagca gacgagcaat tccatttgtt cttctccagc atctctaagg cccacttgaa   3300

tgcaaaggaa aacacttgca cagcaaagca agagaagtca cagcagcaag acacgcacag   3360

tcaaccattt tccgagaaaa aaagaaaatt ccccacttgg aaagaaagag gaggaacact   3420

ggattcttac tttctggatc ttgacactgg gctgcaaaac ctaccttcct ctctcccgcc   3480

tcccctcacc ctcaactctc aatgtcttgc tgtcattttc tgtctcggct ccctcctccc   3540

ccttccccct tcccccaccc cacacccttc accctctgtg tcctggtcct tctgagggcc   3600

actgcagatg actctccttt gaaatgagaa aaagaaaaga aagcaagaac agaaaacgaa   3660

gccacaggaa gggaagtaga cattgtatgc ttatggtttc tcattatgaa ggtgcagctt   3720

gtaggaggtt tgtacggatg tgctttgaag ttatgtatat tacatataac aggaaaaaat   3780

attaaaataa acagtgctgg taagtatgaa gctgacattc taaaattata attatctgac   3840

tgtgattgat gtatcctgag gttcctagat ctcactgaac tggcccagct aaggagacct   3900

ggactctggg tgtgggttgg ctcacagtag gggctgacgg gttcagtgta gtaatactgt   3960

gtgtggtgtt tgtaattggt tgattggtgg ggaggggtgg ggggccctaa tggagaggtg   4020

tgggtttggc aagaaagaag caacacagat gtcgtcccca aaatgccagt tcaagacacc   4080

ttctccctgc ccccctggta gtaacagtca gggcctggtc tgtgctcagg tactgggtcc   4140

cagtctggga ctctgctgct gaagttgcca cagtagaggt ccctggctta gtccttatct   4200

ccctacgggg cttgccttgg ttttcagtct tctctctctt tctctctttt tttttttttt   4260

gccacattct gcccttccct gaccccattg taataaccaa ctccatatcc aaagggaggt   4320

ggtgctctca gccattgtag aagatggtgg ctttaacctg actgtctaaa aattcccagc   4380

taagcctttt cctctactct cttccttgtt ctgaatcatt tcttcttctc aggccaaagt   4440

agccatggta aggaggcttc atggggcaga ccctgaaaga tcaaaactgc atttgcaaag   4500

ccctcccctg tcccaggaca aagctgagac tgacgggtga tgttgctcat aggctccagc   4560

tctgcataag accttggctt ggagacctcc ctctcagtca acagctgaac tctgagcttg   4620

tgcccagaaa ttaccccaag accacaggaa cccttcaaga agctcccatc acaagcttgg   4680

cattgctctc tgccacacgt gggcttcctc aggcttgtct gccacaagct acttctctga   4740

gctcagaaag tgccccttga tgagggaaaa tgtcccactg cactgcgaat ttctcagttc   4800

cattttacct cccagtcctc cttctaaacc agttaataaa ttcattccac aagtatttac   4860

tgattacctg cttgtgccag ggactattct caggctgaag aaggtgggag gggagggcgg   4920

aacctgagga gccacctgag ccagctttat atttcaacca tggctggccc atctgagagc   4980

atctccccac tctcgccaac ctatcggggc atagcccagg gatgccccca ggcggcccag   5040

gttagatgcg tccctttggc ttgtcagtga tgacatacac cttagctgct tagctggtgc   5100

tggcctgagg cagggcagga aatcagaata gcatttgctt ctctgggcaa atgggaagtt   5160

cagcggggca gcagaatcag tggcattccc cctggtgcag gccggtgggt ccactccaac   5220

tccccctgag tgtagcagca cactttccat acaccaggtt ctttctacaa tcctggtgga   5280

aaagccacag aaccttcttc ctgcccttct tgagagttcc ccctctttct gggtcaagag   5340

ctggagtggt ggctccatcc tctctgggcc acttcggtct aggaactcat ctttgcagga   5400

accaggagtc ctgagcacac tgaacacacc tcagagggag gatccttgtt gtggattttg   5460

cacctggctt tggggcaggg gtgaagtgac caggcttagc ttgtggagtt tatgggccac   5520

cagggtttgg ggaaatcacc atcccgcgga tgctgtgacc tcccttctac ggagatgcag   5580

gcagtgccac gagggaggag gggacctgca aagctagaat ctagggcact gtttcctccc   5640

catccttctc tttgtagaga atagagacgt ttgtcttgtc tgtcttcaac ctacttttcc   5700

ttttctcttt tttgtttctc atcctctctg tgccacctct ccacccagga ggccatgtag   5760

catagtggaa aaagtccctg agggcggtta ggagttctgg gtgaccatcc tggctcagct   5820

cctaactcac catgtgacat caggctatcc ccattccccc tcttgggcct cagtttcccg   5880

acttgcaaaa taagcagaaa gaaccagatg ctctccaggg tctttttcta ctttgctatc   5940

tcatgggtct tcattttctc ttattttgtt ttctctggat cttttccatc tgagggtaca   6000

ggaagtacca ggacctgttt cagtttttga atcctgcaag cacattccaa gactggcctg   6060

aaactgcatg agcaacatca ctcgaaataa tttttttttt caaaagcacc ttaacaacca   6120

attgcgatgc tgtcctgttc ctttttactc acacccttct ctcctttctc gtccccatgc   6180

tcccccacct cagtgctccg tgctgtatgc gtgtgctctc tgttcttgta tactcaatat   6240

aagtgaaata aatgtgtttg atgctgaacc ata                                6273


<210>  10094
<211>  880
<212>  PRT
<213>  Homo sapiens

<400>  10094

Met Thr Thr Glu Thr Gly Pro Asp Ser Glu Val Lys Lys Ala Gln Glu 
1               5                   10                  15


Glu Ala Pro Gln Gln Pro Glu Ala Ala Ala Ala Val Thr Thr Pro Val 
            20                  25                  30


Thr Pro Ala Gly His Gly His Pro Glu Ala Asn Ser Asn Glu Lys His 
        35                  40                  45


Pro Ser Gln Gln Asp Thr Arg Pro Ala Glu Gln Ser Leu Asp Met Glu 
    50                  55                  60


Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr Thr Pro 
65                  70                  75                  80


Ser Lys Ala Gln Lys Ser Pro Gln Lys Ile Ala Lys Lys Tyr Lys Ser 
                85                  90                  95


Ala Ile Cys Arg Val Thr Leu Leu Asp Ala Ser Glu Tyr Glu Cys Glu 
            100                 105                 110


Val Glu Lys His Gly Arg Gly Gln Val Leu Phe Asp Leu Val Cys Glu 
        115                 120                 125


His Leu Asn Leu Leu Glu Lys Asp Tyr Phe Gly Leu Thr Phe Cys Asp 
    130                 135                 140


Ala Asp Ser Gln Lys Asn Trp Leu Asp Pro Ser Lys Glu Ile Lys Lys 
145                 150                 155                 160


Gln Ile Arg Ser Ser Pro Trp Asn Phe Ala Phe Thr Val Lys Phe Tyr 
                165                 170                 175


Pro Pro Asp Pro Ala Gln Leu Thr Glu Asp Ile Thr Arg Tyr Tyr Leu 
            180                 185                 190


Cys Leu Gln Leu Arg Ala Asp Ile Ile Thr Gly Arg Leu Pro Cys Ser 
        195                 200                 205


Phe Val Thr His Ala Leu Leu Gly Ser Tyr Ala Val Gln Ala Glu Leu 
    210                 215                 220


Gly Asp Tyr Asp Ala Glu Glu His Val Gly Asn Tyr Val Ser Glu Leu 
225                 230                 235                 240


Arg Phe Ala Pro Asn Gln Thr Arg Glu Leu Glu Glu Arg Ile Met Glu 
                245                 250                 255


Leu His Lys Thr Tyr Arg Gly Met Thr Pro Gly Glu Ala Glu Ile His 
            260                 265                 270


Phe Leu Glu Asn Ala Lys Lys Leu Ser Met Tyr Gly Val Asp Leu His 
        275                 280                 285


His Ala Lys Asp Ser Glu Gly Ile Asp Ile Met Leu Gly Val Cys Ala 
    290                 295                 300


Asn Gly Leu Leu Ile Tyr Arg Asp Arg Leu Arg Ile Asn Arg Phe Ala 
305                 310                 315                 320


Trp Pro Lys Ile Leu Lys Ile Ser Tyr Lys Arg Ser Asn Phe Tyr Ile 
                325                 330                 335


Lys Ile Arg Pro Gly Glu Tyr Glu Gln Phe Glu Ser Thr Ile Gly Phe 
            340                 345                 350


Lys Leu Pro Asn His Arg Ser Ala Lys Arg Leu Trp Lys Val Cys Ile 
        355                 360                 365


Glu His His Thr Phe Phe Arg Leu Val Ser Pro Glu Pro Pro Pro Lys 
    370                 375                 380


Gly Phe Leu Val Met Gly Ser Lys Phe Arg Tyr Ser Gly Arg Thr Gln 
385                 390                 395                 400


Ala Gln Thr Arg Gln Ala Ser Ala Leu Ile Asp Arg Pro Ala Pro Phe 
                405                 410                 415


Phe Glu Arg Ser Ser Ser Lys Arg Tyr Thr Met Ser Arg Ser Leu Asp 
            420                 425                 430


Gly Ala Glu Phe Ser Arg Pro Ala Ser Val Ser Glu Asn His Asp Ala 
        435                 440                 445


Gly Pro Asp Gly Asp Lys Arg Asp Glu Asp Gly Glu Ser Gly Gly Gln 
    450                 455                 460


Arg Ser Glu Ala Glu Glu Gly Glu Val Arg Thr Pro Thr Lys Ile Lys 
465                 470                 475                 480


Glu Leu Lys Pro Glu Gln Glu Thr Thr Pro Arg His Lys Gln Glu Phe 
                485                 490                 495


Leu Asp Lys Pro Glu Asp Val Leu Leu Lys His Gln Ala Ser Ile Asn 
            500                 505                 510


Glu Leu Lys Arg Thr Leu Lys Glu Pro Asn Ser Lys Leu Ile His Arg 
        515                 520                 525


Asp Arg Asp Trp Glu Arg Glu Arg Arg Leu Pro Ser Ser Pro Ala Ser 
    530                 535                 540


Pro Ser Pro Lys Gly Thr Pro Glu Lys Ala Asn Glu Arg Ala Gly Leu 
545                 550                 555                 560


Arg Glu Gly Ser Glu Glu Lys Val Lys Pro Pro Arg Pro Arg Ala Pro 
                565                 570                 575


Glu Ser Asp Thr Gly Asp Glu Asp Gln Asp Gln Glu Arg Asp Thr Val 
            580                 585                 590


Phe Leu Lys Asp Asn His Leu Ala Ile Glu Arg Lys Cys Ser Ser Ile 
        595                 600                 605


Thr Val Ser Ser Thr Ser Ser Leu Glu Ala Glu Val Asp Phe Thr Val 
    610                 615                 620


Ile Gly Asp Tyr His Gly Ser Ala Phe Glu Asp Phe Ser Arg Ser Leu 
625                 630                 635                 640


Pro Glu Leu Asp Arg Asp Lys Ser Asp Ser Asp Thr Glu Gly Leu Leu 
                645                 650                 655


Phe Ser Arg Asp Leu Asn Lys Gly Ala Pro Ser Gln Asp Asp Glu Ser 
            660                 665                 670


Gly Gly Ile Glu Asp Ser Pro Asp Arg Gly Ala Cys Ser Thr Pro Asp 
        675                 680                 685


Met Pro Gln Phe Glu Pro Val Lys Thr Glu Thr Met Thr Val Ser Ser 
    690                 695                 700


Leu Ala Ile Arg Lys Lys Ile Glu Pro Glu Ala Val Leu Gln Thr Arg 
705                 710                 715                 720


Val Ser Ala Met Asp Asn Thr Gln Val Asp Gly Ser Ala Ser Val Gly 
                725                 730                 735


Arg Glu Phe Ile Ala Thr Thr Pro Ser Ile Thr Thr Glu Thr Ile Ser 
            740                 745                 750


Thr Thr Met Glu Asn Ser Leu Lys Ser Gly Lys Gly Ala Ala Ala Met 
        755                 760                 765


Ile Pro Gly Pro Gln Thr Val Ala Thr Glu Ile Arg Ser Leu Ser Pro 
    770                 775                 780


Ile Ile Gly Lys Asp Val Leu Thr Ser Thr Tyr Gly Ala Thr Ala Glu 
785                 790                 795                 800


Thr Leu Ser Thr Ser Thr Thr Thr His Val Thr Lys Thr Val Lys Gly 
                805                 810                 815


Gly Phe Ser Glu Thr Arg Ile Glu Lys Arg Ile Ile Ile Thr Gly Asp 
            820                 825                 830


Glu Asp Val Asp Gln Asp Gln Ala Leu Ala Leu Ala Ile Lys Glu Ala 
        835                 840                 845


Lys Leu Gln His Pro Asp Met Leu Val Thr Lys Ala Val Val Tyr Arg 
    850                 855                 860


Glu Thr Asp Pro Ser Pro Glu Glu Arg Asp Lys Lys Pro Gln Glu Ser 
865                 870                 875                 880


<210>  10095
<211>  2764
<212>  DNA
<213>  Homo sapiens

<400>  10095
agacatggag gagaaggact acagtgaggc cgatggcctt tcggagagga ccacgccctt     60

caccctctgt gtcctggtcc ttctgagggc cactgcagat gactctcctt tgaaatgaga    120

aaaagaaaag aaagcaagaa cagaaaacga agccacagga agggaagtag acattgtatg    180

cttatggttt ctcattatga aggtgcagct tgtaggaggt ttgtacggat gtgctttgaa    240

gttatgtata ttacatataa caggaaaaaa tattaaaata aacagtgctg gtaagtatga    300

agctgacatt ctaaaattat aattatctga ctgtgattga tgtatcctga ggttcctaga    360

tctcactgaa ctggcccagc taaggagacc tggactctgg gtgtgggttg gctcacagta    420

ggggctgacg ggttcagtgt agtaatactg tgtgtggtgt ttgtaattgg ttgattggtg    480

gggaggggtg gggggcccta atggagaggt gtgggtttgg caagaaagaa gcaacacaga    540

tgtcgtcccc aaaatgccag ttcaagacac cttctccctg cccccctggt agtaacagtc    600

agggcctggt ctgtgctcag gtactgggtc ccagtctggg actctgctgc tgaagttgcc    660

acagtagagg tccctggctt agtccttatc tccctacggg gcttgccttg gttttcagtc    720

ttctctctct ttctctcttt tttttttttt tgccacattc tgcccttccc tgaccccatt    780

gtaataacca actccatatc caaagggagg tggtgctctc agccattgta gaagatggtg    840

gctttaacct gactgtctaa aaattcccag ctaagccttt tcctctactc tcttccttgt    900

tctgaatcat ttcttcttct caggccaaag tagccatggt aaggaggctt catggggcag    960

accctgaaag atcaaaactg catttgcaaa gccctcccct gtcccaggac aaagctgaga   1020

ctgacgggtg atgttgctca taggctccag ctctgcataa gaccttggct tggagacctc   1080

cctctcagtc aacagctgaa ctctgagctt gtgcccagaa attaccccaa gaccacagga   1140

acccttcaag aagctcccat cacaagcttg gcattgctct ctgccacacg tgggcttcct   1200

caggcttgtc tgccacaagc tacttctctg agctcagaaa gtgccccttg atgagggaaa   1260

atgtcccact gcactgcgaa tttctcagtt ccattttacc tcccagtcct ccttctaaac   1320

cagttaataa attcattcca caagtattta ctgattacct gcttgtgcca gggactattc   1380

tcaggctgaa gaaggtggga ggggagggcg gaacctgagg agccacctga gccagcttta   1440

tatttcaacc atggctggcc catctgagag catctcccca ctctcgccaa cctatcgggg   1500

catagcccag ggatgccccc aggcggccca ggttagatgc gtccctttgg cttgtcagtg   1560

atgacataca ccttagctgc ttagctggtg ctggcctgag gcagggcagg aaatcagaat   1620

agcatttgct tctctgggca aatgggaagt tcagcggggc agcagaatca gtggcattcc   1680

ccctggtgca ggccggtggg tccactccaa ctccccctga gtgtagcagc acactttcca   1740

tacaccaggt tctttctaca atcctggtgg aaaagccaca gaaccttctt cctgcccttc   1800

ttgagagttc cccctctttc tgggtcaaga gctggagtgg tggctccatc ctctctgggc   1860

cacttcggtc taggaactca tctttgcagg aaccaggagt cctgagcaca ctgaacacac   1920

ctcagaggga ggatccttgt tgtggatttt gcacctggct ttggggcagg ggtgaagtga   1980

ccaggcttag cttgtggagt ttatgggcca ccagggtttg gggaaatcac catcccgcgg   2040

atgctgtgac ctcccttcta cggagatgca ggcagtgcca cgagggagga ggggacctgc   2100

aaagctagaa tctagggcac tgtttcctcc ccatccttct ctttgtagag aatagagacg   2160

tttgtcttgt ctgtcttcaa cctacttttc cttttctctt ttttgtttct catcctctct   2220

gtgccacctc tccacccagg aggccatgta gcatagtgga aaaagtccct gagggcggtt   2280

aggagttctg ggtgaccatc ctggctcagc tcctaactca ccatgtgaca tcaggctatc   2340

cccattcccc ctcttgggcc tcagtttccc gacttgcaaa ataagcagaa agaaccagat   2400

gctctccagg gtctttttct actttgctat ctcatgggtc ttcattttct cttattttgt   2460

tttctctgga tcttttccat ctgagggtac aggaagtacc aggacctgtt tcagtttttg   2520

aatcctgcaa gcacattcca agactggcct gaaactgcat gagcaacatc actcgaaata   2580

attttttttt tcaaaagcac cttaacaacc aattgcgatg ctgtcctgtt cctttttact   2640

cacacccttc tctcctttct cgtccccatg ctcccccacc tcagtgctcc gtgctgtatg   2700

cgtgtgctct ctgttcttgt atactcaata taagtgaaat aaatgtgttt gatgctgaac   2760

cata                                                                2764


<210>  10096
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  10096

Met Glu Glu Lys Asp Tyr Ser Glu Ala Asp Gly Leu Ser Glu Arg Thr 
1               5                   10                  15


Thr Pro Phe Thr Leu Cys Val Leu Val Leu Leu Arg Ala Thr Ala Asp 
            20                  25                  30


Asp Ser Pro Leu Lys 
        35


<210>  10097
<211>  5285
<212>  DNA
<213>  Homo sapiens

<400>  10097
gagggcgcgc ggaggacccg ccgccgccgg tgtgaggcgg cccgtcctgg ctcccttgtc     60

cgggaagccc gcccaggagc cgccgccggg tcccgctcgt ctgccgcctc agcctcagcc    120

ccaacctcag ccgccgccgt tgcgcttgct cccgggcggt cctggcctgt gccgccgccg    180

cccccagcgt cggagccatg gcgggcgccg cgtccccttg cgccaacggc tgcgggcccg    240

gcgcgccctc ggacgccgag gtgctgcacc tctgccgcag cctcgaggtg ggcaccgtca    300

tgactttgtt ctactccaag aagtcgcagc gacccgagcg gaagaccttc caggtcaagc    360

tggagacgcg ccagatcacg tggagccggg gcgccgacaa gatcgagggg gccattgaca    420

ttcgtgaaat taaggagatc cgcccaggga agacctcacg ggactttgat cgctatcaag    480

aggacccagc tttccggccg gaccagtcac attgctttgt cattctctat ggaatggaat    540

ttcgcctgaa aacgctgagc ctgcaagcca catctgagga tgaagtgaac atgtggatca    600

agggcttaac ttggctgatg gaggatacat tgcaggcacc cacacccctg cagattgaga    660

ggtggctccg gaagcagttt tactcagtgg atcggaatcg tgaggatcgt atatcagcca    720

aggacctgaa gaacatgctg tcccaggtca actaccgggt ccccaacatg cgcttcctcc    780

gagagcggct gacggacctg gagcagcgca gcggggacat cacctacggg cagtttgctc    840

agctgtaccg cagcctcatg tacagcgccc agaagacgat ggacctcccc ttcttggaag    900

ccagtactct gagggctggg gagcggccgg agctttgccg agtgtccctt cctgagttcc    960

agcagttcct tcttgactac cagggggagc tgtgggctgt tgatcgcctc caggtgcagg   1020

agttcatgct cagcttcctc cgagacccct tacgagagat cgaggagcca tacttcttcc   1080

tggatgagtt tgtcaccttc ctgttctcca aagagaacag tgtgtggaac tcgcagctgg   1140

atgcagtatg cccggacacc atgaacaacc ctctttccca ctactggatc tcctcctcgc   1200

acaacacgta cctgaccggg gaccagttct ccagtgagtc ctccttggaa gcctatgctc   1260

gctgcctgcg gatgggctgt cgctgcattg agttggactg ctgggacggc ccggatggga   1320

tgccagttat ttaccatggg cacaccctta ccaccaagat caagttctca gatgtcctgc   1380

acaccatcaa ggagcatgcc tttgtggcct cagagtaccc agtcatcctg tccattgagg   1440

accactgcag cattgcccag cagagaaaca tggcccaata cttcaagaag gtgctggggg   1500

acacactcct caccaagccc gtggagatct ctgccgacgg gctcccctca cccaaccagc   1560

ttaagaggaa gatcctcatc aagcacaaga agctggctga gggcagtgcc tacgaggagg   1620

tgcctacatc catgatgtac tctgagaacg acatcagcaa ctctatcaag aatggcatcc   1680

tctacctgga ggaccctgtg aaccacgaat ggtatcccca ctactttgtt ctgaccagca   1740

gcaagatcta ctactctgag gagaccagca gtgaccaggg caacgaggat gaggaggagc   1800

ccaaggaggt cagcagcagc acagagctgc actccaatga gaagtggttc catgggaagc   1860

taggggcagg gcgtgacggg cgtcacatcg ctgagcgcct gcttactgag tactgcatcg   1920

agaccggagc ccctgacggc tccttcctcg tgcgagagag tgagaccttc gtgggcgact   1980

acacgctctc tttctggcgg aacgggaaag tccagcactg ccgtatccac tcccggcaag   2040

atgctgggac ccccaagttc ttcttgacag acaacctcgt ctttgactcc ctctatgacc   2100

tcatcacgca ctaccagcag gtgcccctgc gctgtaatga gtttgagatg cgactttcag   2160

agcctgtccc acagaccaac gcccacgaga gcaaagagtg gtaccacgcg agcctgacca   2220

gagcacaggc tgagcacatg ctaatgcgcg tccctcgtga tggggccttc ctggtgcgga   2280

agcggaatga acccaactca tatgccatct ctttccgggc tgagggcaag atcaagcatt   2340

gccgtgtcca gcaagagggc cagacagtga tgctagggaa ctcggagttc gacagccttg   2400

ttgacctcat cagctactat gagaaacacc cgctataccg caagatgaag ctgcgctatc   2460

ccatcaacga ggaggcactg gagaagattg gcacagctga gcctgactac ggggccctgt   2520

atgagggacg caaccctggc ttctatgtag aggcaaaccc tatgccaact ttcaagtgtg   2580

cagtcaaagc cctctttgac tacaaggccc agagggagga cgagctgacc ttcatcaaga   2640

gcgccatcat ccagaatgtg gagaagcaag agggaggctg gtggcgaggg gactacggag   2700

ggaagaagca gctgtggttc ccatcaaact acgtggaaga gatggtcaac cccgtggccc   2760

tggagccgga gagggagcac ttggacgaga acagccccct aggggacttg ctgcgggggg   2820

tcttggatgt gccggcttgt cagattgcca tccgtcctga gggcaagaac aaccggctct   2880

tcgtcttctc catcagcatg gcgtcggtgg cccactggtc cctggatgtt gctgccgact   2940

cacaggagga gctgcaggac tgggtgaaaa agatccgtga agtggcccag acagcagacg   3000

ccaggctcac tgaagggaag ataatggaac ggaggaagaa gattgccctg gagctctctg   3060

aacttgtcgt ctactgccgg cctgttccct ttgatgaaga gaagattggc acagaacgtg   3120

cttgctaccg ggacatgtca tccttcccgg aaaccaaggc tgagaaatac gtgaacaagg   3180

ccaaaggcaa gaagttcctt cagtacaatc gactgcagct ctcccgcatc taccccaagg   3240

gccagcgact ggattcctcc aactacgatc ctttgcccat gtggatctgt ggcagtcagc   3300

ttgtggccct caacttccag acccctgaca agcctatgca gatgaaccag gccctcttca   3360

tgacgggcag gcactgtggc tacgtgctgc agccaagcac catgcgggat gaggccttcg   3420

acccctttga caagagcagc ctccgcgggc tggagccatg tgccatctct attgaggtgc   3480

tgggggcccg acatctgcca aagaatggcc gaggcattgt gtgtcctttt gtggagattg   3540

aggtggctgg agctgagtat gacagcacca agcagaagac agagtttgtg gtggacaatg   3600

gactcaaccc tgtatggcca gccaagccct tccacttcca gatcagtaac cctgaatttg   3660

cctttctgcg cttcgtggtg tatgaggaag acatgtttag tgaccagaat ttcctggctc   3720

aggctacttt cccagtaaaa ggcctgaaga caggatacag agcagtgcct ttgaagaaca   3780

actacagtga ggacctggag ttggcctccc tgctgatcaa gattgacatt ttccctgcca   3840

agcaggagaa tggtgacctc agtcccttca gtggtacgtc cctgcgggag cggggctcag   3900

atgcctcagg ccagctgttt catggccgag cccgggaagg ctcctttgaa tcccgctacc   3960

agcagccgtt tgaggacttc cgcatctccc aggagcatct cgcagaccat tttgacagtc   4020

gagaacgaag ggccccaaga aggactcggg tcaatggaga caaccgcctc tagttgtacc   4080

ccagcctcgt tggagagcag caggtgctgt gcgccttgta gaatgccgcg aactgggttc   4140

tttggaagca gccccctgtg gcggccttcc gggtctcgca gcctgaagcc tggattccag   4200

cagtgaatgc tagacagaaa ccaagccatt aatgagatgt tattactgtt ttgggcctcc   4260

atgccccagc tctggatgaa ggcaaaaact gtactgtgtt tcgcattaag cacacacatc   4320

tggccctgac ttctggagat ggatccttcc atcttgtggg gccaggacca tggccgaagc   4380

cccttggaga gagaggctgc ctcagccagt ggcacaggag actccaagga gctactgaca   4440

ttcctaagag tggaggagga ggaggagcct tgctgggcca gggaaacaaa gtttacattg   4500

tcctgtagct ttaaaaccac agctgggcag ggtgagaagc tagatgcccc tgcagtttgg   4560

ccctggagcc agggcagagg aatgtagggc ctgcatggag aagggttctg ccctgcctga   4620

ggaggaggac acagcacaag ggcacattgc ccatggctgg gaacatgacc cagcctgaaa   4680

gatacagggg atcatgttaa aaatagcagt attatttttc gtctcaatgg tattgtaact   4740

aagttattta ctcctcctgc tcctcacccc tgtagggaaa ccttggagag gagagtggca   4800

ggtgggctgc ctgctgtgtt aagaggactt agtttgtgat gtaaggcact gtcaggaatg   4860

gggggcgggc cagggtggga agagaagaaa tagcagagcc tattttggtg aggttttttg   4920

tttttaagtc aaagaagact cagtatgctt tccctgagga atgaaaaagg gattgaggag   4980

ttgcctgact cctgggtggg tggggtacag gcagttaggt gctgaatgaa gctgccatcc   5040

ttgctgcagc ttctaactgg taaaaagatc cagggatgga gatgggaagg ttagaaaggc   5100

agccctcacc tctgaggaca gaggccgggg tccaggcccg tgggcgcaaa ggtgcctcat   5160

agcatagcca gcattcagca cacacaaacc tactgcccac atttgggctc agggttggcc   5220

atttgctagt tctgctgccc tcttaagatc tgactgccaa ataaatcatc ctcatgtcct   5280

ttttc                                                               5285


<210>  10098
<211>  1291
<212>  PRT
<213>  Homo sapiens

<400>  10098

Met Ala Gly Ala Ala Ser Pro Cys Ala Asn Gly Cys Gly Pro Gly Ala 
1               5                   10                  15


Pro Ser Asp Ala Glu Val Leu His Leu Cys Arg Ser Leu Glu Val Gly 
            20                  25                  30


Thr Val Met Thr Leu Phe Tyr Ser Lys Lys Ser Gln Arg Pro Glu Arg 
        35                  40                  45


Lys Thr Phe Gln Val Lys Leu Glu Thr Arg Gln Ile Thr Trp Ser Arg 
    50                  55                  60


Gly Ala Asp Lys Ile Glu Gly Ala Ile Asp Ile Arg Glu Ile Lys Glu 
65                  70                  75                  80


Ile Arg Pro Gly Lys Thr Ser Arg Asp Phe Asp Arg Tyr Gln Glu Asp 
                85                  90                  95


Pro Ala Phe Arg Pro Asp Gln Ser His Cys Phe Val Ile Leu Tyr Gly 
            100                 105                 110


Met Glu Phe Arg Leu Lys Thr Leu Ser Leu Gln Ala Thr Ser Glu Asp 
        115                 120                 125


Glu Val Asn Met Trp Ile Lys Gly Leu Thr Trp Leu Met Glu Asp Thr 
    130                 135                 140


Leu Gln Ala Pro Thr Pro Leu Gln Ile Glu Arg Trp Leu Arg Lys Gln 
145                 150                 155                 160


Phe Tyr Ser Val Asp Arg Asn Arg Glu Asp Arg Ile Ser Ala Lys Asp 
                165                 170                 175


Leu Lys Asn Met Leu Ser Gln Val Asn Tyr Arg Val Pro Asn Met Arg 
            180                 185                 190


Phe Leu Arg Glu Arg Leu Thr Asp Leu Glu Gln Arg Ser Gly Asp Ile 
        195                 200                 205


Thr Tyr Gly Gln Phe Ala Gln Leu Tyr Arg Ser Leu Met Tyr Ser Ala 
    210                 215                 220


Gln Lys Thr Met Asp Leu Pro Phe Leu Glu Ala Ser Thr Leu Arg Ala 
225                 230                 235                 240


Gly Glu Arg Pro Glu Leu Cys Arg Val Ser Leu Pro Glu Phe Gln Gln 
                245                 250                 255


Phe Leu Leu Asp Tyr Gln Gly Glu Leu Trp Ala Val Asp Arg Leu Gln 
            260                 265                 270


Val Gln Glu Phe Met Leu Ser Phe Leu Arg Asp Pro Leu Arg Glu Ile 
        275                 280                 285


Glu Glu Pro Tyr Phe Phe Leu Asp Glu Phe Val Thr Phe Leu Phe Ser 
    290                 295                 300


Lys Glu Asn Ser Val Trp Asn Ser Gln Leu Asp Ala Val Cys Pro Asp 
305                 310                 315                 320


Thr Met Asn Asn Pro Leu Ser His Tyr Trp Ile Ser Ser Ser His Asn 
                325                 330                 335


Thr Tyr Leu Thr Gly Asp Gln Phe Ser Ser Glu Ser Ser Leu Glu Ala 
            340                 345                 350


Tyr Ala Arg Cys Leu Arg Met Gly Cys Arg Cys Ile Glu Leu Asp Cys 
        355                 360                 365


Trp Asp Gly Pro Asp Gly Met Pro Val Ile Tyr His Gly His Thr Leu 
    370                 375                 380


Thr Thr Lys Ile Lys Phe Ser Asp Val Leu His Thr Ile Lys Glu His 
385                 390                 395                 400


Ala Phe Val Ala Ser Glu Tyr Pro Val Ile Leu Ser Ile Glu Asp His 
                405                 410                 415


Cys Ser Ile Ala Gln Gln Arg Asn Met Ala Gln Tyr Phe Lys Lys Val 
            420                 425                 430


Leu Gly Asp Thr Leu Leu Thr Lys Pro Val Glu Ile Ser Ala Asp Gly 
        435                 440                 445


Leu Pro Ser Pro Asn Gln Leu Lys Arg Lys Ile Leu Ile Lys His Lys 
    450                 455                 460


Lys Leu Ala Glu Gly Ser Ala Tyr Glu Glu Val Pro Thr Ser Met Met 
465                 470                 475                 480


Tyr Ser Glu Asn Asp Ile Ser Asn Ser Ile Lys Asn Gly Ile Leu Tyr 
                485                 490                 495


Leu Glu Asp Pro Val Asn His Glu Trp Tyr Pro His Tyr Phe Val Leu 
            500                 505                 510


Thr Ser Ser Lys Ile Tyr Tyr Ser Glu Glu Thr Ser Ser Asp Gln Gly 
        515                 520                 525


Asn Glu Asp Glu Glu Glu Pro Lys Glu Val Ser Ser Ser Thr Glu Leu 
    530                 535                 540


His Ser Asn Glu Lys Trp Phe His Gly Lys Leu Gly Ala Gly Arg Asp 
545                 550                 555                 560


Gly Arg His Ile Ala Glu Arg Leu Leu Thr Glu Tyr Cys Ile Glu Thr 
                565                 570                 575


Gly Ala Pro Asp Gly Ser Phe Leu Val Arg Glu Ser Glu Thr Phe Val 
            580                 585                 590


Gly Asp Tyr Thr Leu Ser Phe Trp Arg Asn Gly Lys Val Gln His Cys 
        595                 600                 605


Arg Ile His Ser Arg Gln Asp Ala Gly Thr Pro Lys Phe Phe Leu Thr 
    610                 615                 620


Asp Asn Leu Val Phe Asp Ser Leu Tyr Asp Leu Ile Thr His Tyr Gln 
625                 630                 635                 640


Gln Val Pro Leu Arg Cys Asn Glu Phe Glu Met Arg Leu Ser Glu Pro 
                645                 650                 655


Val Pro Gln Thr Asn Ala His Glu Ser Lys Glu Trp Tyr His Ala Ser 
            660                 665                 670


Leu Thr Arg Ala Gln Ala Glu His Met Leu Met Arg Val Pro Arg Asp 
        675                 680                 685


Gly Ala Phe Leu Val Arg Lys Arg Asn Glu Pro Asn Ser Tyr Ala Ile 
    690                 695                 700


Ser Phe Arg Ala Glu Gly Lys Ile Lys His Cys Arg Val Gln Gln Glu 
705                 710                 715                 720


Gly Gln Thr Val Met Leu Gly Asn Ser Glu Phe Asp Ser Leu Val Asp 
                725                 730                 735


Leu Ile Ser Tyr Tyr Glu Lys His Pro Leu Tyr Arg Lys Met Lys Leu 
            740                 745                 750


Arg Tyr Pro Ile Asn Glu Glu Ala Leu Glu Lys Ile Gly Thr Ala Glu 
        755                 760                 765


Pro Asp Tyr Gly Ala Leu Tyr Glu Gly Arg Asn Pro Gly Phe Tyr Val 
    770                 775                 780


Glu Ala Asn Pro Met Pro Thr Phe Lys Cys Ala Val Lys Ala Leu Phe 
785                 790                 795                 800


Asp Tyr Lys Ala Gln Arg Glu Asp Glu Leu Thr Phe Ile Lys Ser Ala 
                805                 810                 815


Ile Ile Gln Asn Val Glu Lys Gln Glu Gly Gly Trp Trp Arg Gly Asp 
            820                 825                 830


Tyr Gly Gly Lys Lys Gln Leu Trp Phe Pro Ser Asn Tyr Val Glu Glu 
        835                 840                 845


Met Val Asn Pro Val Ala Leu Glu Pro Glu Arg Glu His Leu Asp Glu 
    850                 855                 860


Asn Ser Pro Leu Gly Asp Leu Leu Arg Gly Val Leu Asp Val Pro Ala 
865                 870                 875                 880


Cys Gln Ile Ala Ile Arg Pro Glu Gly Lys Asn Asn Arg Leu Phe Val 
                885                 890                 895


Phe Ser Ile Ser Met Ala Ser Val Ala His Trp Ser Leu Asp Val Ala 
            900                 905                 910


Ala Asp Ser Gln Glu Glu Leu Gln Asp Trp Val Lys Lys Ile Arg Glu 
        915                 920                 925


Val Ala Gln Thr Ala Asp Ala Arg Leu Thr Glu Gly Lys Ile Met Glu 
    930                 935                 940


Arg Arg Lys Lys Ile Ala Leu Glu Leu Ser Glu Leu Val Val Tyr Cys 
945                 950                 955                 960


Arg Pro Val Pro Phe Asp Glu Glu Lys Ile Gly Thr Glu Arg Ala Cys 
                965                 970                 975


Tyr Arg Asp Met Ser Ser Phe Pro Glu Thr Lys Ala Glu Lys Tyr Val 
            980                 985                 990


Asn Lys Ala Lys Gly Lys Lys Phe Leu Gln Tyr Asn Arg Leu Gln Leu 
        995                 1000                1005


Ser Arg Ile Tyr Pro Lys Gly Gln Arg Leu Asp Ser Ser Asn Tyr Asp 
    1010                1015                1020


Pro Leu Pro Met Trp Ile Cys Gly Ser Gln Leu Val Ala Leu Asn Phe 
1025                1030                1035                1040


Gln Thr Pro Asp Lys Pro Met Gln Met Asn Gln Ala Leu Phe Met Thr 
                1045                1050                1055


Gly Arg His Cys Gly Tyr Val Leu Gln Pro Ser Thr Met Arg Asp Glu 
            1060                1065                1070


Ala Phe Asp Pro Phe Asp Lys Ser Ser Leu Arg Gly Leu Glu Pro Cys 
        1075                1080                1085


Ala Ile Ser Ile Glu Val Leu Gly Ala Arg His Leu Pro Lys Asn Gly 
    1090                1095                1100


Arg Gly Ile Val Cys Pro Phe Val Glu Ile Glu Val Ala Gly Ala Glu 
1105                1110                1115                1120


Tyr Asp Ser Thr Lys Gln Lys Thr Glu Phe Val Val Asp Asn Gly Leu 
                1125                1130                1135


Asn Pro Val Trp Pro Ala Lys Pro Phe His Phe Gln Ile Ser Asn Pro 
            1140                1145                1150


Glu Phe Ala Phe Leu Arg Phe Val Val Tyr Glu Glu Asp Met Phe Ser 
        1155                1160                1165


Asp Gln Asn Phe Leu Ala Gln Ala Thr Phe Pro Val Lys Gly Leu Lys 
    1170                1175                1180


Thr Gly Tyr Arg Ala Val Pro Leu Lys Asn Asn Tyr Ser Glu Asp Leu 
1185                1190                1195                1200


Glu Leu Ala Ser Leu Leu Ile Lys Ile Asp Ile Phe Pro Ala Lys Gln 
                1205                1210                1215


Glu Asn Gly Asp Leu Ser Pro Phe Ser Gly Thr Ser Leu Arg Glu Arg 
            1220                1225                1230


Gly Ser Asp Ala Ser Gly Gln Leu Phe His Gly Arg Ala Arg Glu Gly 
        1235                1240                1245


Ser Phe Glu Ser Arg Tyr Gln Gln Pro Phe Glu Asp Phe Arg Ile Ser 
    1250                1255                1260


Gln Glu His Leu Ala Asp His Phe Asp Ser Arg Glu Arg Arg Ala Pro 
1265                1270                1275                1280


Arg Arg Thr Arg Val Asn Gly Asp Asn Arg Leu 
                1285                1290


<210>  10099
<211>  5842
<212>  DNA
<213>  Homo sapiens

<400>  10099
gagggcgcgc ggaggacccg ccgccgccgg tgtgaggcgg cccgtcctgg ctcccttgtc     60

cgggaagccc gcccaggagc cgccgccggg tcccgctcgt ctgccgcctc agcctcagcc    120

ccaacctcag ccgccgccgt tgcgcttgct cccgggcggt cctggcctgt gccgccgccg    180

cccccagcgt cggagccatg gcgggcgccg cgtccccttg cgccaacggc tgcgggcccg    240

gcgcgccctc ggacgccgag gtgctgcacc tctgccgcag cctcgaggtg ggcaccgtca    300

tgactttgtt ctactccaag aagtcgcagc gacccgagcg gaagaccttc caggtcaagc    360

tggagacgcg ccagatcacg tggagccggg gcgccgacaa gatcgagggg gccattgaca    420

ttcgtgaaat taaggagatc cgcccaggga agacctcacg ggactttgat cgctatcaag    480

aggacccagc tttccggccg gaccagtcac attgctttgt cattctctat ggaatggaat    540

ttcgcctgaa aacgctgagc ctgcaagcca catctgagga tgaagtgaac atgtggatca    600

agggcttaac ttggctgatg gaggatacat tgcaggcacc cacacccctg cagattgaga    660

ggtggctccg gaagcagttt tactcagtgg atcggaatcg tgaggatcgt atatcagcca    720

aggacctgaa gaacatgctg tcccaggtca actaccgggt ccccaacatg cgcttcctcc    780

gagagcggct gacggacctg gagcagcgca gcggggacat cacctacggg cagtttgctc    840

agctgtaccg cagcctcatg tacagcgccc agaagacgat ggacctcccc ttcttggaag    900

ccagtactct gagggctggg gagcggccgg agctttgccg agtgtccctt cctgagttcc    960

agcagttcct tcttgactac cagggggagc tgtgggctgt tgatcgcctc caggtgcagg   1020

agttcatgct cagcttcctc cgagacccct tacgagagat cgaggagcca tacttcttcc   1080

tggatgagtt tgtcaccttc ctgttctcca aagagaacag tgtgtggaac tcgcagctgg   1140

atgcagtatg cccggacacc atgaacaacc ctctttccca ctactggatc tcctcctcgc   1200

acaacacgta cctgaccggg gaccagttct ccagtgagtc ctccttggaa gcctatgctc   1260

gctgcctgcg gatgggctgt cgctgcattg agttggactg ctgggacggc ccggatggga   1320

tgccagttat ttaccatggg cacaccctta ccaccaagat caagttctca gatgtcctgc   1380

acaccatcaa ggagcatgcc tttgtggcct cagagtaccc agtcatcctg tccattgagg   1440

accactgcag cattgcccag cagagaaaca tggcccaata cttcaagaag gtgctggggg   1500

acacactcct caccaagccc gtggagatct ctgccgacgg gctcccctca cccaaccagc   1560

ttaagaggaa gatcctcatc aagcacaaga agctggctga gggcagtgcc tacgaggagg   1620

tgcctacatc catgatgtac tctgagaacg acatcagcaa ctctatcaag aatggcatcc   1680

tctacctgga ggaccctgtg aaccacgaat ggtatcccca ctactttgtt ctgaccagca   1740

gcaagatcta ctactctgag gagaccagca gtgaccaggg caacgaggat gaggaggagc   1800

ccaaggaggt cagcagcagc acagagctgc actccaatga gaagtggttc catgggaagc   1860

taggggcagg gcgtgacggg cgtcacatcg ctgagcgcct gcttactgag tactgcatcg   1920

agaccggagc ccctgacggc tccttcctcg tgcgagagag tgagaccttc gtgggcgact   1980

acacgctctc tttctggcgg aacgggaaag tccagcactg ccgtatccac tcccggcaag   2040

atgctgggac ccccaagttc ttcttgacag acaacctcgt ctttgactcc ctctatgacc   2100

tcatcacgca ctaccagcag gtgcccctgc gctgtaatga gtttgagatg cgactttcag   2160

agcctgtccc acagaccaac gcccacgaga gcaaagagtg gtaccacgcg agcctgacca   2220

gagcacaggc tgagcacatg ctaatgcgcg tccctcgtga tggggccttc ctggtgcgga   2280

agcggaatga acccaactca tatgccatct ctttccgggc tgagggcaag atcaagcatt   2340

gccgtgtcca gcaagagggc cagacagtga tgctagggaa ctcggagttc gacagccttg   2400

ttgacctcat cagctactat gagaaacacc cgctataccg caagatgaag ctgcgctatc   2460

ccatcaacga ggaggcactg gagaagattg gcacagctga gcctgactac ggggccctgt   2520

atgagggacg caaccctggc ttctatgtag aggcaaaccc tatgccaact ttcaagtgtg   2580

cagtcaaagc cctctttgac tacaaggccc agagggagga cgagctgacc ttcatcaaga   2640

gcgccatcat ccagaatgtg gagaagcaag agggaggctg gtggcgaggg gactacggag   2700

ggaagaagca gctgtggttc ccatcaaact acgtggaaga gatggtcaac cccgtggccc   2760

tggagccgga gagggagcac ttggacgaga acagccccct aggggacttg ctgcgggggg   2820

tcttggatgt gccggcttgt cagattgcca tccgtcctga gggcaagaac aaccggctct   2880

tcgtcttctc catcagcatg gcgtcggtgg cccactggtc cctggatgtt gctgccgact   2940

cacaggagga gctgcaggac tgggtgaaaa agatccgtga agtggcccag acagcagacg   3000

ccaggctcac tgaagggaag ataatggaac ggaggaagaa gattgccctg gagctctctg   3060

aacttgtcgt ctactgccgg cctgttccct ttgatgaaga gaagattggc acagaacgtg   3120

cttgctaccg ggacatgtca tccttcccgg aaaccaaggc tgagaaatac gtgaacaagg   3180

ccaaaggcaa gaagttcctt cagtacaatc gactgcagct ctcccgcatc taccccaagg   3240

gccagcgact ggattcctcc aactacgatc ctttgcccat gtggatctgt ggcagtcagc   3300

ttgtggccct caacttccag acccctgaca agcctatgca gatgaaccag gccctcttca   3360

tgacgggcag gcactgtggc tacgtgctgc agccaagcac catgcgggat gaggccttcg   3420

acccctttga caagagcagc ctccgcgggc tggagccatg tgccatctct attgaggtgc   3480

tgggggcccg acatctgcca aagaatggcc gaggcattgt gtgtcctttt gtggagattg   3540

aggtggctgg agctgagtat gacagcacca agcagaagac agagtttgtg gtggacaatg   3600

gactcaaccc tgtatggcca gccaagccct tccacttcca gatcagtaac cctgaatttg   3660

cctttctgcg cttcgtggtg tatgaggaag acatgtttag tgaccagaat ttcctggctc   3720

aggctacttt cccagtaaaa ggcctgaaga caggatacag agcagtgcct ttgaagaaca   3780

actacagtga ggacctggag ttggcctccc tgctgatcaa gattgacatt ttccctgcca   3840

agcaggagaa tggtgacctc agtcccttca gtggtacgtc cctgcgggag cggggctcag   3900

atgcctcagg ccagctgttt catggccgag cccgggaagg ctcctttgaa tcccgctacc   3960

agcagccgtt tgaggacttc cgcatctccc aggagcatct cgcagaccat tttgacagtc   4020

gagaacgaag ggccccaaga aggactcggg tcaatggaga caaccgcctc tagttgtacc   4080

ccagcctcgt tggagagcag caggtgctgt gcgccttgta gaatgccgcg aactgggttc   4140

tttggaagca gccccctgtg gcggccttcc gggtctcgca gcctgaagcc tggattccag   4200

cagtgaatgc tagacagaaa ccaagccatt aatgagatgt tattactgtt ttgggcctcc   4260

atgccccagc tctggatgaa ggcaaaaact gtactgtgtt tcgcattaag cacacacatc   4320

tggccctgac ttctggagat ggatccttcc atcttgtggg gccaggacca tggccgaagc   4380

cccttggaga gagaggctgc ctcagccagt ggcacaggag actccaagga gctactgaca   4440

ttcctaagag tggaggagga ggaggagcct tgctgggcca gggaaacaaa gtttacattg   4500

tcctgtagct ttaaaaccac agctgggcag ggtgagaagc tagatgcccc tgcagtttgg   4560

ccctggagcc agggcagagg aatgtagggc ctgcatggag aagggttctg ccctgcctga   4620

ggaggaggac acagcacaag ggcacattgc ccatggctgg gaacatgacc cagcctgaaa   4680

gatacagggg atcatgttaa aaatagcagt attatttttc gtctcaatgg tattgtaact   4740

aagttattta ctcctcctgc tcctcacccc tgtagggaaa ccttggagag gagagtggca   4800

ggtgggctgc ctgctgtgtt aagaggactt agtttgtgat gtaaggcact gtcaggaatg   4860

gggggcgggc cagggtggga agagaagaaa tagcagagcc tattttggtg aggttttttg   4920

tttttaagtc aaagaagact cagtatgctt tccctgagga atgaaaaagg gattgaggag   4980

ttgcctgact cctgggtggg tggggtacag gcagttaggt gctgaatgaa gctgccatcc   5040

ttgctgcagc ttctaactgg taaaaagatc cagggatgga gatgggaagg ttagaaaggc   5100

agccctcacc tctgaggaca gaggccgggg tccaggcccg tgggcgcaaa ggtgcctcat   5160

agcatagcca gcattcagca cacacaaacc tactgcccac atttgggctc agggttggcc   5220

atttgctagt tctgctgccc tcttaagatc tgactgccaa ataaatcatc ctcatgtcct   5280

ttttcctttg acttgtatgc tctttcgggg gctcaggaaa gcctgttgca tgggacatgc   5340

tcactagaaa cagtcgccag atgattattc tgcagtagaa gcaggtagga aatttctgga   5400

aatttctcag gttaagcagc aagagctgta acccctcctc tgggctaaca ggagttgtgg   5460

gtccactctc tcctgcccac cctctgaggg tgtgtctgag cagagtacat cctgcctggg   5520

ttctttgtgg ccagccagtt ttggtggtga gctggaaaca accagagccc ctttccagtt   5580

ccacagaaac ctctcctttc aaaaatgttg cattcagttc gttaacactg ccaggtgcca   5640

ttctgattgc ctctaggact tggcagctga aatctctggg ccctttcaac acagttgaaa   5700

ggcccttctc ttcctgaagc tctgtttcca tagttggctg tgctgggatg gaacaaaaat   5760

gacgccacac aaaaaattta agatagatcc ggttccgtgg atgacatgaa ctgatgatag   5820

ccagtatcaa acagcgatag tg                                            5842


<210>  10100
<211>  1291
<212>  PRT
<213>  Homo sapiens

<400>  10100

Met Ala Gly Ala Ala Ser Pro Cys Ala Asn Gly Cys Gly Pro Gly Ala 
1               5                   10                  15


Pro Ser Asp Ala Glu Val Leu His Leu Cys Arg Ser Leu Glu Val Gly 
            20                  25                  30


Thr Val Met Thr Leu Phe Tyr Ser Lys Lys Ser Gln Arg Pro Glu Arg 
        35                  40                  45


Lys Thr Phe Gln Val Lys Leu Glu Thr Arg Gln Ile Thr Trp Ser Arg 
    50                  55                  60


Gly Ala Asp Lys Ile Glu Gly Ala Ile Asp Ile Arg Glu Ile Lys Glu 
65                  70                  75                  80


Ile Arg Pro Gly Lys Thr Ser Arg Asp Phe Asp Arg Tyr Gln Glu Asp 
                85                  90                  95


Pro Ala Phe Arg Pro Asp Gln Ser His Cys Phe Val Ile Leu Tyr Gly 
            100                 105                 110


Met Glu Phe Arg Leu Lys Thr Leu Ser Leu Gln Ala Thr Ser Glu Asp 
        115                 120                 125


Glu Val Asn Met Trp Ile Lys Gly Leu Thr Trp Leu Met Glu Asp Thr 
    130                 135                 140


Leu Gln Ala Pro Thr Pro Leu Gln Ile Glu Arg Trp Leu Arg Lys Gln 
145                 150                 155                 160


Phe Tyr Ser Val Asp Arg Asn Arg Glu Asp Arg Ile Ser Ala Lys Asp 
                165                 170                 175


Leu Lys Asn Met Leu Ser Gln Val Asn Tyr Arg Val Pro Asn Met Arg 
            180                 185                 190


Phe Leu Arg Glu Arg Leu Thr Asp Leu Glu Gln Arg Ser Gly Asp Ile 
        195                 200                 205


Thr Tyr Gly Gln Phe Ala Gln Leu Tyr Arg Ser Leu Met Tyr Ser Ala 
    210                 215                 220


Gln Lys Thr Met Asp Leu Pro Phe Leu Glu Ala Ser Thr Leu Arg Ala 
225                 230                 235                 240


Gly Glu Arg Pro Glu Leu Cys Arg Val Ser Leu Pro Glu Phe Gln Gln 
                245                 250                 255


Phe Leu Leu Asp Tyr Gln Gly Glu Leu Trp Ala Val Asp Arg Leu Gln 
            260                 265                 270


Val Gln Glu Phe Met Leu Ser Phe Leu Arg Asp Pro Leu Arg Glu Ile 
        275                 280                 285


Glu Glu Pro Tyr Phe Phe Leu Asp Glu Phe Val Thr Phe Leu Phe Ser 
    290                 295                 300


Lys Glu Asn Ser Val Trp Asn Ser Gln Leu Asp Ala Val Cys Pro Asp 
305                 310                 315                 320


Thr Met Asn Asn Pro Leu Ser His Tyr Trp Ile Ser Ser Ser His Asn 
                325                 330                 335


Thr Tyr Leu Thr Gly Asp Gln Phe Ser Ser Glu Ser Ser Leu Glu Ala 
            340                 345                 350


Tyr Ala Arg Cys Leu Arg Met Gly Cys Arg Cys Ile Glu Leu Asp Cys 
        355                 360                 365


Trp Asp Gly Pro Asp Gly Met Pro Val Ile Tyr His Gly His Thr Leu 
    370                 375                 380


Thr Thr Lys Ile Lys Phe Ser Asp Val Leu His Thr Ile Lys Glu His 
385                 390                 395                 400


Ala Phe Val Ala Ser Glu Tyr Pro Val Ile Leu Ser Ile Glu Asp His 
                405                 410                 415


Cys Ser Ile Ala Gln Gln Arg Asn Met Ala Gln Tyr Phe Lys Lys Val 
            420                 425                 430


Leu Gly Asp Thr Leu Leu Thr Lys Pro Val Glu Ile Ser Ala Asp Gly 
        435                 440                 445


Leu Pro Ser Pro Asn Gln Leu Lys Arg Lys Ile Leu Ile Lys His Lys 
    450                 455                 460


Lys Leu Ala Glu Gly Ser Ala Tyr Glu Glu Val Pro Thr Ser Met Met 
465                 470                 475                 480


Tyr Ser Glu Asn Asp Ile Ser Asn Ser Ile Lys Asn Gly Ile Leu Tyr 
                485                 490                 495


Leu Glu Asp Pro Val Asn His Glu Trp Tyr Pro His Tyr Phe Val Leu 
            500                 505                 510


Thr Ser Ser Lys Ile Tyr Tyr Ser Glu Glu Thr Ser Ser Asp Gln Gly 
        515                 520                 525


Asn Glu Asp Glu Glu Glu Pro Lys Glu Val Ser Ser Ser Thr Glu Leu 
    530                 535                 540


His Ser Asn Glu Lys Trp Phe His Gly Lys Leu Gly Ala Gly Arg Asp 
545                 550                 555                 560


Gly Arg His Ile Ala Glu Arg Leu Leu Thr Glu Tyr Cys Ile Glu Thr 
                565                 570                 575


Gly Ala Pro Asp Gly Ser Phe Leu Val Arg Glu Ser Glu Thr Phe Val 
            580                 585                 590


Gly Asp Tyr Thr Leu Ser Phe Trp Arg Asn Gly Lys Val Gln His Cys 
        595                 600                 605


Arg Ile His Ser Arg Gln Asp Ala Gly Thr Pro Lys Phe Phe Leu Thr 
    610                 615                 620


Asp Asn Leu Val Phe Asp Ser Leu Tyr Asp Leu Ile Thr His Tyr Gln 
625                 630                 635                 640


Gln Val Pro Leu Arg Cys Asn Glu Phe Glu Met Arg Leu Ser Glu Pro 
                645                 650                 655


Val Pro Gln Thr Asn Ala His Glu Ser Lys Glu Trp Tyr His Ala Ser 
            660                 665                 670


Leu Thr Arg Ala Gln Ala Glu His Met Leu Met Arg Val Pro Arg Asp 
        675                 680                 685


Gly Ala Phe Leu Val Arg Lys Arg Asn Glu Pro Asn Ser Tyr Ala Ile 
    690                 695                 700


Ser Phe Arg Ala Glu Gly Lys Ile Lys His Cys Arg Val Gln Gln Glu 
705                 710                 715                 720


Gly Gln Thr Val Met Leu Gly Asn Ser Glu Phe Asp Ser Leu Val Asp 
                725                 730                 735


Leu Ile Ser Tyr Tyr Glu Lys His Pro Leu Tyr Arg Lys Met Lys Leu 
            740                 745                 750


Arg Tyr Pro Ile Asn Glu Glu Ala Leu Glu Lys Ile Gly Thr Ala Glu 
        755                 760                 765


Pro Asp Tyr Gly Ala Leu Tyr Glu Gly Arg Asn Pro Gly Phe Tyr Val 
    770                 775                 780


Glu Ala Asn Pro Met Pro Thr Phe Lys Cys Ala Val Lys Ala Leu Phe 
785                 790                 795                 800


Asp Tyr Lys Ala Gln Arg Glu Asp Glu Leu Thr Phe Ile Lys Ser Ala 
                805                 810                 815


Ile Ile Gln Asn Val Glu Lys Gln Glu Gly Gly Trp Trp Arg Gly Asp 
            820                 825                 830


Tyr Gly Gly Lys Lys Gln Leu Trp Phe Pro Ser Asn Tyr Val Glu Glu 
        835                 840                 845


Met Val Asn Pro Val Ala Leu Glu Pro Glu Arg Glu His Leu Asp Glu 
    850                 855                 860


Asn Ser Pro Leu Gly Asp Leu Leu Arg Gly Val Leu Asp Val Pro Ala 
865                 870                 875                 880


Cys Gln Ile Ala Ile Arg Pro Glu Gly Lys Asn Asn Arg Leu Phe Val 
                885                 890                 895


Phe Ser Ile Ser Met Ala Ser Val Ala His Trp Ser Leu Asp Val Ala 
            900                 905                 910


Ala Asp Ser Gln Glu Glu Leu Gln Asp Trp Val Lys Lys Ile Arg Glu 
        915                 920                 925


Val Ala Gln Thr Ala Asp Ala Arg Leu Thr Glu Gly Lys Ile Met Glu 
    930                 935                 940


Arg Arg Lys Lys Ile Ala Leu Glu Leu Ser Glu Leu Val Val Tyr Cys 
945                 950                 955                 960


Arg Pro Val Pro Phe Asp Glu Glu Lys Ile Gly Thr Glu Arg Ala Cys 
                965                 970                 975


Tyr Arg Asp Met Ser Ser Phe Pro Glu Thr Lys Ala Glu Lys Tyr Val 
            980                 985                 990


Asn Lys Ala Lys Gly Lys Lys Phe Leu Gln Tyr Asn Arg Leu Gln Leu 
        995                 1000                1005


Ser Arg Ile Tyr Pro Lys Gly Gln Arg Leu Asp Ser Ser Asn Tyr Asp 
    1010                1015                1020


Pro Leu Pro Met Trp Ile Cys Gly Ser Gln Leu Val Ala Leu Asn Phe 
1025                1030                1035                1040


Gln Thr Pro Asp Lys Pro Met Gln Met Asn Gln Ala Leu Phe Met Thr 
                1045                1050                1055


Gly Arg His Cys Gly Tyr Val Leu Gln Pro Ser Thr Met Arg Asp Glu 
            1060                1065                1070


Ala Phe Asp Pro Phe Asp Lys Ser Ser Leu Arg Gly Leu Glu Pro Cys 
        1075                1080                1085


Ala Ile Ser Ile Glu Val Leu Gly Ala Arg His Leu Pro Lys Asn Gly 
    1090                1095                1100


Arg Gly Ile Val Cys Pro Phe Val Glu Ile Glu Val Ala Gly Ala Glu 
1105                1110                1115                1120


Tyr Asp Ser Thr Lys Gln Lys Thr Glu Phe Val Val Asp Asn Gly Leu 
                1125                1130                1135


Asn Pro Val Trp Pro Ala Lys Pro Phe His Phe Gln Ile Ser Asn Pro 
            1140                1145                1150


Glu Phe Ala Phe Leu Arg Phe Val Val Tyr Glu Glu Asp Met Phe Ser 
        1155                1160                1165


Asp Gln Asn Phe Leu Ala Gln Ala Thr Phe Pro Val Lys Gly Leu Lys 
    1170                1175                1180


Thr Gly Tyr Arg Ala Val Pro Leu Lys Asn Asn Tyr Ser Glu Asp Leu 
1185                1190                1195                1200


Glu Leu Ala Ser Leu Leu Ile Lys Ile Asp Ile Phe Pro Ala Lys Gln 
                1205                1210                1215


Glu Asn Gly Asp Leu Ser Pro Phe Ser Gly Thr Ser Leu Arg Glu Arg 
            1220                1225                1230


Gly Ser Asp Ala Ser Gly Gln Leu Phe His Gly Arg Ala Arg Glu Gly 
        1235                1240                1245


Ser Phe Glu Ser Arg Tyr Gln Gln Pro Phe Glu Asp Phe Arg Ile Ser 
    1250                1255                1260


Gln Glu His Leu Ala Asp His Phe Asp Ser Arg Glu Arg Arg Ala Pro 
1265                1270                1275                1280


Arg Arg Thr Arg Val Asn Gly Asp Asn Arg Leu 
                1285                1290


<210>  10101
<211>  5493
<212>  DNA
<213>  Homo sapiens

<400>  10101
gccgctcgtg gccgccgggc tgtgtccggg gccgcgtgag aaagctctgc gggactgagg     60

gctgggtggg tcgaccggga acggcgcgcg ctcccgccgc catcgcgcct ccgtccccgc    120

ctgcggcctg tctgggggtc gcggggcgca ggcgcggcgg gccgacgggc gggggtcctc    180

cccacgggtg cgcgggcgcc tttgttcccg gcgccgaagc ggggtggggc ctcagggcag    240

ccccgccccg ccgcgctgag gccccgcccc gtgtccgcct gcaggagccg ccgccgggtc    300

ccgctcgtct gccgcctcag cctcagcccc aacctcagcc gccgccgttg cgcttgctcc    360

cgggcggtcc tggcctgtgc cgccgccgcc cccagcgtcg gagccatggc gggcgccgcg    420

tccccttgcg ccaacggctg cgggcccggc gcgccctcgg acgccgaggt gctgcacctc    480

tgccgcagcc tcgaggtggg caccgtcatg actttgttct actccaagaa gtcgcagcga    540

cccgagcgga agaccttcca ggtcaagctg gagacgcgcc agatcacgtg gagccggggc    600

gccgacaaga tcgagggggc cattgacatt cgtgaaatta aggagatccg cccagggaag    660

acctcacggg actttgatcg ctatcaagag gacccagctt tccggccgga ccagtcacat    720

tgctttgtca ttctctatgg aatggaattt cgcctgaaaa cgctgagcct gcaagccaca    780

tctgaggatg aagtgaacat gtggatcaag ggcttaactt ggctgatgga ggatacattg    840

caggcaccca cacccctgca gattgagagg tggctccgga agcagtttta ctcagtggat    900

cggaatcgtg aggatcgtat atcagccaag gacctgaaga acatgctgtc ccaggtcaac    960

taccgggtcc ccaacatgcg cttcctccga gagcggctga cggacctgga gcagcgcagc   1020

ggggacatca cctacgggca gtttgctcag ctgtaccgca gcctcatgta cagcgcccag   1080

aagacgatgg acctcccctt cttggaagcc agtactctga gggctgggga gcggccggag   1140

ctttgccgag tgtcccttcc tgagttccag cagttccttc ttgactacca gggggagctg   1200

tgggctgttg atcgcctcca ggtgcaggag ttcatgctca gcttcctccg agacccctta   1260

cgagagatcg aggagccata cttcttcctg gatgagtttg tcaccttcct gttctccaaa   1320

gagaacagtg tgtggaactc gcagctggat gcagtatgcc cggacaccat gaacaaccct   1380

ctttcccact actggatctc ctcctcgcac aacacgtacc tgaccgggga ccagttctcc   1440

agtgagtcct ccttggaagc ctatgctcgc tgcctgcgga tgggctgtcg ctgcattgag   1500

ttggactgct gggacggccc ggatgggatg ccagttattt accatgggca cacccttacc   1560

accaagatca agttctcaga tgtcctgcac accatcaagg agcatgcctt tgtggcctca   1620

gagtacccag tcatcctgtc cattgaggac cactgcagca ttgcccagca gagaaacatg   1680

gcccaatact tcaagaaggt gctgggggac acactcctca ccaagcccgt ggagatctct   1740

gccgacgggc tcccctcacc caaccagctt aagaggaaga tcctcatcaa gcacaagaag   1800

ctggctgagg gcagtgccta cgaggaggtg cctacatcca tgatgtactc tgagaacgac   1860

atcagcaact ctatcaagaa tggcatcctc tacctggagg accctgtgaa ccacgaatgg   1920

tatccccact actttgttct gaccagcagc aagatctact actctgagga gaccagcagt   1980

gaccagggca acgaggatga ggaggagccc aaggaggtca gcagcagcac agagctgcac   2040

tccaatgaga agtggttcca tgggaagcta ggggcagggc gtgacgggcg tcacatcgct   2100

gagcgcctgc ttactgagta ctgcatcgag accggagccc ctgacggctc cttcctcgtg   2160

cgagagagtg agaccttcgt gggcgactac acgctctctt tctggcggaa cgggaaagtc   2220

cagcactgcc gtatccactc ccggcaagat gctgggaccc ccaagttctt cttgacagac   2280

aacctcgtct ttgactccct ctatgacctc atcacgcact accagcaggt gcccctgcgc   2340

tgtaatgagt ttgagatgcg actttcagag cctgtcccac agaccaacgc ccacgagagc   2400

aaagagtggt accacgcgag cctgaccaga gcacaggctg agcacatgct aatgcgcgtc   2460

cctcgtgatg gggccttcct ggtgcggaag cggaatgaac ccaactcata tgccatctct   2520

ttccgggctg agggcaagat caagcattgc cgtgtccagc aagagggcca gacagtgatg   2580

ctagggaact cggagttcga cagccttgtt gacctcatca gctactatga gaaacacccg   2640

ctataccgca agatgaagct gcgctatccc atcaacgagg aggcactgga gaagattggc   2700

acagctgagc ctgactacgg ggccctgtat gagggacgca accctggctt ctatgtagag   2760

gcaaacccta tgccaacttt caagtgtgca gtcaaagccc tctttgacta caaggcccag   2820

agggaggacg agctgacctt catcaagagc gccatcatcc agaatgtgga gaagcaagag   2880

ggaggctggt ggcgagggga ctacggaggg aagaagcagc tgtggttccc atcaaactac   2940

gtggaagaga tggtcaaccc cgtggccctg gagccggaga gggagcactt ggacgagaac   3000

agccccctag gggacttgct gcggggggtc ttggatgtgc cggcttgtca gattgccatc   3060

cgtcctgagg gcaagaacaa ccggctcttc gtcttctcca tcagcatggc gtcggtggcc   3120

cactggtccc tggatgttgc tgccgactca caggaggagc tgcaggactg ggtgaaaaag   3180

atccgtgaag tggcccagac agcagacgcc aggctcactg aagggaagat aatggaacgg   3240

aggaagaaga ttgccctgga gctctctgaa cttgtcgtct actgccggcc tgttcccttt   3300

gatgaagaga agattggcac agaacgtgct tgctaccggg acatgtcatc cttcccggaa   3360

accaaggctg agaaatacgt gaacaaggcc aaaggcaaga agttccttca gtacaatcga   3420

ctgcagctct cccgcatcta ccccaagggc cagcgactgg attcctccaa ctacgatcct   3480

ttgcccatgt ggatctgtgg cagtcagctt gtggccctca acttccagac ccctgacaag   3540

cctatgcaga tgaaccaggc cctcttcatg acgggcaggc actgtggcta cgtgctgcag   3600

ccaagcacca tgcgggatga ggccttcgac ccctttgaca agagcagcct ccgcgggctg   3660

gagccatgtg ccatctctat tgaggtgctg ggggcccgac atctgccaaa gaatggccga   3720

ggcattgtgt gtccttttgt ggagattgag gtggctggag ctgagtatga cagcaccaag   3780

cagaagacag agtttgtggt ggacaatgga ctcaaccctg tatggccagc caagcccttc   3840

cacttccaga tcagtaaccc tgaatttgcc tttctgcgct tcgtggtgta tgaggaagac   3900

atgtttagtg accagaattt cctggctcag gctactttcc cagtaaaagg cctgaagaca   3960

ggatacagag cagtgccttt gaagaacaac tacagtgagg acctggagtt ggcctccctg   4020

ctgatcaaga ttgacatttt ccctgccaag caggagaatg gtgacctcag tcccttcagt   4080

ggtacgtccc tgcgggagcg gggctcagat gcctcaggcc agctgtttca tggccgagcc   4140

cgggaaggct cctttgaatc ccgctaccag cagccgtttg aggacttccg catctcccag   4200

gagcatctcg cagaccattt tgacagtcga gaacgaaggg ccccaagaag gactcgggtc   4260

aatggagaca accgcctcta gttgtacccc agcctcgttg gagagcagca ggtgctgtgc   4320

gccttgtaga atgccgcgaa ctgggttctt tggaagcagc cccctgtggc ggccttccgg   4380

gtctcgcagc ctgaagcctg gattccagca gtgaatgcta gacagaaacc aagccattaa   4440

tgagatgtta ttactgtttt gggcctccat gccccagctc tggatgaagg caaaaactgt   4500

actgtgtttc gcattaagca cacacatctg gccctgactt ctggagatgg atccttccat   4560

cttgtggggc caggaccatg gccgaagccc cttggagaga gaggctgcct cagccagtgg   4620

cacaggagac tccaaggagc tactgacatt cctaagagtg gaggaggagg aggagccttg   4680

ctgggccagg gaaacaaagt ttacattgtc ctgtagcttt aaaaccacag ctgggcaggg   4740

tgagaagcta gatgcccctg cagtttggcc ctggagccag ggcagaggaa tgtagggcct   4800

gcatggagaa gggttctgcc ctgcctgagg aggaggacac agcacaaggg cacattgccc   4860

atggctggga acatgaccca gcctgaaaga tacaggggat catgttaaaa atagcagtat   4920

tatttttcgt ctcaatggta ttgtaactaa gttatttact cctcctgctc ctcacccctg   4980

tagggaaacc ttggagagga gagtggcagg tgggctgcct gctgtgttaa gaggacttag   5040

tttgtgatgt aaggcactgt caggaatggg gggcgggcca gggtgggaag agaagaaata   5100

gcagagccta ttttggtgag gttttttgtt tttaagtcaa agaagactca gtatgctttc   5160

cctgaggaat gaaaaaggga ttgaggagtt gcctgactcc tgggtgggtg gggtacaggc   5220

agttaggtgc tgaatgaagc tgccatcctt gctgcagctt ctaactggta aaaagatcca   5280

gggatggaga tgggaaggtt agaaaggcag ccctcacctc tgaggacaga ggccggggtc   5340

caggcccgtg ggcgcaaagg tgcctcatag catagccagc attcagcaca cacaaaccta   5400

ctgcccacat ttgggctcag ggttggccat ttgctagttc tgctgccctc ttaagatctg   5460

actgccaaat aaatcatcct catgtccttt ttc                                5493


<210>  10102
<211>  1291
<212>  PRT
<213>  Homo sapiens

<400>  10102

Met Ala Gly Ala Ala Ser Pro Cys Ala Asn Gly Cys Gly Pro Gly Ala 
1               5                   10                  15


Pro Ser Asp Ala Glu Val Leu His Leu Cys Arg Ser Leu Glu Val Gly 
            20                  25                  30


Thr Val Met Thr Leu Phe Tyr Ser Lys Lys Ser Gln Arg Pro Glu Arg 
        35                  40                  45


Lys Thr Phe Gln Val Lys Leu Glu Thr Arg Gln Ile Thr Trp Ser Arg 
    50                  55                  60


Gly Ala Asp Lys Ile Glu Gly Ala Ile Asp Ile Arg Glu Ile Lys Glu 
65                  70                  75                  80


Ile Arg Pro Gly Lys Thr Ser Arg Asp Phe Asp Arg Tyr Gln Glu Asp 
                85                  90                  95


Pro Ala Phe Arg Pro Asp Gln Ser His Cys Phe Val Ile Leu Tyr Gly 
            100                 105                 110


Met Glu Phe Arg Leu Lys Thr Leu Ser Leu Gln Ala Thr Ser Glu Asp 
        115                 120                 125


Glu Val Asn Met Trp Ile Lys Gly Leu Thr Trp Leu Met Glu Asp Thr 
    130                 135                 140


Leu Gln Ala Pro Thr Pro Leu Gln Ile Glu Arg Trp Leu Arg Lys Gln 
145                 150                 155                 160


Phe Tyr Ser Val Asp Arg Asn Arg Glu Asp Arg Ile Ser Ala Lys Asp 
                165                 170                 175


Leu Lys Asn Met Leu Ser Gln Val Asn Tyr Arg Val Pro Asn Met Arg 
            180                 185                 190


Phe Leu Arg Glu Arg Leu Thr Asp Leu Glu Gln Arg Ser Gly Asp Ile 
        195                 200                 205


Thr Tyr Gly Gln Phe Ala Gln Leu Tyr Arg Ser Leu Met Tyr Ser Ala 
    210                 215                 220


Gln Lys Thr Met Asp Leu Pro Phe Leu Glu Ala Ser Thr Leu Arg Ala 
225                 230                 235                 240


Gly Glu Arg Pro Glu Leu Cys Arg Val Ser Leu Pro Glu Phe Gln Gln 
                245                 250                 255


Phe Leu Leu Asp Tyr Gln Gly Glu Leu Trp Ala Val Asp Arg Leu Gln 
            260                 265                 270


Val Gln Glu Phe Met Leu Ser Phe Leu Arg Asp Pro Leu Arg Glu Ile 
        275                 280                 285


Glu Glu Pro Tyr Phe Phe Leu Asp Glu Phe Val Thr Phe Leu Phe Ser 
    290                 295                 300


Lys Glu Asn Ser Val Trp Asn Ser Gln Leu Asp Ala Val Cys Pro Asp 
305                 310                 315                 320


Thr Met Asn Asn Pro Leu Ser His Tyr Trp Ile Ser Ser Ser His Asn 
                325                 330                 335


Thr Tyr Leu Thr Gly Asp Gln Phe Ser Ser Glu Ser Ser Leu Glu Ala 
            340                 345                 350


Tyr Ala Arg Cys Leu Arg Met Gly Cys Arg Cys Ile Glu Leu Asp Cys 
        355                 360                 365


Trp Asp Gly Pro Asp Gly Met Pro Val Ile Tyr His Gly His Thr Leu 
    370                 375                 380


Thr Thr Lys Ile Lys Phe Ser Asp Val Leu His Thr Ile Lys Glu His 
385                 390                 395                 400


Ala Phe Val Ala Ser Glu Tyr Pro Val Ile Leu Ser Ile Glu Asp His 
                405                 410                 415


Cys Ser Ile Ala Gln Gln Arg Asn Met Ala Gln Tyr Phe Lys Lys Val 
            420                 425                 430


Leu Gly Asp Thr Leu Leu Thr Lys Pro Val Glu Ile Ser Ala Asp Gly 
        435                 440                 445


Leu Pro Ser Pro Asn Gln Leu Lys Arg Lys Ile Leu Ile Lys His Lys 
    450                 455                 460


Lys Leu Ala Glu Gly Ser Ala Tyr Glu Glu Val Pro Thr Ser Met Met 
465                 470                 475                 480


Tyr Ser Glu Asn Asp Ile Ser Asn Ser Ile Lys Asn Gly Ile Leu Tyr 
                485                 490                 495


Leu Glu Asp Pro Val Asn His Glu Trp Tyr Pro His Tyr Phe Val Leu 
            500                 505                 510


Thr Ser Ser Lys Ile Tyr Tyr Ser Glu Glu Thr Ser Ser Asp Gln Gly 
        515                 520                 525


Asn Glu Asp Glu Glu Glu Pro Lys Glu Val Ser Ser Ser Thr Glu Leu 
    530                 535                 540


His Ser Asn Glu Lys Trp Phe His Gly Lys Leu Gly Ala Gly Arg Asp 
545                 550                 555                 560


Gly Arg His Ile Ala Glu Arg Leu Leu Thr Glu Tyr Cys Ile Glu Thr 
                565                 570                 575


Gly Ala Pro Asp Gly Ser Phe Leu Val Arg Glu Ser Glu Thr Phe Val 
            580                 585                 590


Gly Asp Tyr Thr Leu Ser Phe Trp Arg Asn Gly Lys Val Gln His Cys 
        595                 600                 605


Arg Ile His Ser Arg Gln Asp Ala Gly Thr Pro Lys Phe Phe Leu Thr 
    610                 615                 620


Asp Asn Leu Val Phe Asp Ser Leu Tyr Asp Leu Ile Thr His Tyr Gln 
625                 630                 635                 640


Gln Val Pro Leu Arg Cys Asn Glu Phe Glu Met Arg Leu Ser Glu Pro 
                645                 650                 655


Val Pro Gln Thr Asn Ala His Glu Ser Lys Glu Trp Tyr His Ala Ser 
            660                 665                 670


Leu Thr Arg Ala Gln Ala Glu His Met Leu Met Arg Val Pro Arg Asp 
        675                 680                 685


Gly Ala Phe Leu Val Arg Lys Arg Asn Glu Pro Asn Ser Tyr Ala Ile 
    690                 695                 700


Ser Phe Arg Ala Glu Gly Lys Ile Lys His Cys Arg Val Gln Gln Glu 
705                 710                 715                 720


Gly Gln Thr Val Met Leu Gly Asn Ser Glu Phe Asp Ser Leu Val Asp 
                725                 730                 735


Leu Ile Ser Tyr Tyr Glu Lys His Pro Leu Tyr Arg Lys Met Lys Leu 
            740                 745                 750


Arg Tyr Pro Ile Asn Glu Glu Ala Leu Glu Lys Ile Gly Thr Ala Glu 
        755                 760                 765


Pro Asp Tyr Gly Ala Leu Tyr Glu Gly Arg Asn Pro Gly Phe Tyr Val 
    770                 775                 780


Glu Ala Asn Pro Met Pro Thr Phe Lys Cys Ala Val Lys Ala Leu Phe 
785                 790                 795                 800


Asp Tyr Lys Ala Gln Arg Glu Asp Glu Leu Thr Phe Ile Lys Ser Ala 
                805                 810                 815


Ile Ile Gln Asn Val Glu Lys Gln Glu Gly Gly Trp Trp Arg Gly Asp 
            820                 825                 830


Tyr Gly Gly Lys Lys Gln Leu Trp Phe Pro Ser Asn Tyr Val Glu Glu 
        835                 840                 845


Met Val Asn Pro Val Ala Leu Glu Pro Glu Arg Glu His Leu Asp Glu 
    850                 855                 860


Asn Ser Pro Leu Gly Asp Leu Leu Arg Gly Val Leu Asp Val Pro Ala 
865                 870                 875                 880


Cys Gln Ile Ala Ile Arg Pro Glu Gly Lys Asn Asn Arg Leu Phe Val 
                885                 890                 895


Phe Ser Ile Ser Met Ala Ser Val Ala His Trp Ser Leu Asp Val Ala 
            900                 905                 910


Ala Asp Ser Gln Glu Glu Leu Gln Asp Trp Val Lys Lys Ile Arg Glu 
        915                 920                 925


Val Ala Gln Thr Ala Asp Ala Arg Leu Thr Glu Gly Lys Ile Met Glu 
    930                 935                 940


Arg Arg Lys Lys Ile Ala Leu Glu Leu Ser Glu Leu Val Val Tyr Cys 
945                 950                 955                 960


Arg Pro Val Pro Phe Asp Glu Glu Lys Ile Gly Thr Glu Arg Ala Cys 
                965                 970                 975


Tyr Arg Asp Met Ser Ser Phe Pro Glu Thr Lys Ala Glu Lys Tyr Val 
            980                 985                 990


Asn Lys Ala Lys Gly Lys Lys Phe Leu Gln Tyr Asn Arg Leu Gln Leu 
        995                 1000                1005


Ser Arg Ile Tyr Pro Lys Gly Gln Arg Leu Asp Ser Ser Asn Tyr Asp 
    1010                1015                1020


Pro Leu Pro Met Trp Ile Cys Gly Ser Gln Leu Val Ala Leu Asn Phe 
1025                1030                1035                1040


Gln Thr Pro Asp Lys Pro Met Gln Met Asn Gln Ala Leu Phe Met Thr 
                1045                1050                1055


Gly Arg His Cys Gly Tyr Val Leu Gln Pro Ser Thr Met Arg Asp Glu 
            1060                1065                1070


Ala Phe Asp Pro Phe Asp Lys Ser Ser Leu Arg Gly Leu Glu Pro Cys 
        1075                1080                1085


Ala Ile Ser Ile Glu Val Leu Gly Ala Arg His Leu Pro Lys Asn Gly 
    1090                1095                1100


Arg Gly Ile Val Cys Pro Phe Val Glu Ile Glu Val Ala Gly Ala Glu 
1105                1110                1115                1120


Tyr Asp Ser Thr Lys Gln Lys Thr Glu Phe Val Val Asp Asn Gly Leu 
                1125                1130                1135


Asn Pro Val Trp Pro Ala Lys Pro Phe His Phe Gln Ile Ser Asn Pro 
            1140                1145                1150


Glu Phe Ala Phe Leu Arg Phe Val Val Tyr Glu Glu Asp Met Phe Ser 
        1155                1160                1165


Asp Gln Asn Phe Leu Ala Gln Ala Thr Phe Pro Val Lys Gly Leu Lys 
    1170                1175                1180


Thr Gly Tyr Arg Ala Val Pro Leu Lys Asn Asn Tyr Ser Glu Asp Leu 
1185                1190                1195                1200


Glu Leu Ala Ser Leu Leu Ile Lys Ile Asp Ile Phe Pro Ala Lys Gln 
                1205                1210                1215


Glu Asn Gly Asp Leu Ser Pro Phe Ser Gly Thr Ser Leu Arg Glu Arg 
            1220                1225                1230


Gly Ser Asp Ala Ser Gly Gln Leu Phe His Gly Arg Ala Arg Glu Gly 
        1235                1240                1245


Ser Phe Glu Ser Arg Tyr Gln Gln Pro Phe Glu Asp Phe Arg Ile Ser 
    1250                1255                1260


Gln Glu His Leu Ala Asp His Phe Asp Ser Arg Glu Arg Arg Ala Pro 
1265                1270                1275                1280


Arg Arg Thr Arg Val Asn Gly Asp Asn Arg Leu 
                1285                1290


<210>  10103
<211>  6050
<212>  DNA
<213>  Homo sapiens

<400>  10103
gccgctcgtg gccgccgggc tgtgtccggg gccgcgtgag aaagctctgc gggactgagg     60

gctgggtggg tcgaccggga acggcgcgcg ctcccgccgc catcgcgcct ccgtccccgc    120

ctgcggcctg tctgggggtc gcggggcgca ggcgcggcgg gccgacgggc gggggtcctc    180

cccacgggtg cgcgggcgcc tttgttcccg gcgccgaagc ggggtggggc ctcagggcag    240

ccccgccccg ccgcgctgag gccccgcccc gtgtccgcct gcaggagccg ccgccgggtc    300

ccgctcgtct gccgcctcag cctcagcccc aacctcagcc gccgccgttg cgcttgctcc    360

cgggcggtcc tggcctgtgc cgccgccgcc cccagcgtcg gagccatggc gggcgccgcg    420

tccccttgcg ccaacggctg cgggcccggc gcgccctcgg acgccgaggt gctgcacctc    480

tgccgcagcc tcgaggtggg caccgtcatg actttgttct actccaagaa gtcgcagcga    540

cccgagcgga agaccttcca ggtcaagctg gagacgcgcc agatcacgtg gagccggggc    600

gccgacaaga tcgagggggc cattgacatt cgtgaaatta aggagatccg cccagggaag    660

acctcacggg actttgatcg ctatcaagag gacccagctt tccggccgga ccagtcacat    720

tgctttgtca ttctctatgg aatggaattt cgcctgaaaa cgctgagcct gcaagccaca    780

tctgaggatg aagtgaacat gtggatcaag ggcttaactt ggctgatgga ggatacattg    840

caggcaccca cacccctgca gattgagagg tggctccgga agcagtttta ctcagtggat    900

cggaatcgtg aggatcgtat atcagccaag gacctgaaga acatgctgtc ccaggtcaac    960

taccgggtcc ccaacatgcg cttcctccga gagcggctga cggacctgga gcagcgcagc   1020

ggggacatca cctacgggca gtttgctcag ctgtaccgca gcctcatgta cagcgcccag   1080

aagacgatgg acctcccctt cttggaagcc agtactctga gggctgggga gcggccggag   1140

ctttgccgag tgtcccttcc tgagttccag cagttccttc ttgactacca gggggagctg   1200

tgggctgttg atcgcctcca ggtgcaggag ttcatgctca gcttcctccg agacccctta   1260

cgagagatcg aggagccata cttcttcctg gatgagtttg tcaccttcct gttctccaaa   1320

gagaacagtg tgtggaactc gcagctggat gcagtatgcc cggacaccat gaacaaccct   1380

ctttcccact actggatctc ctcctcgcac aacacgtacc tgaccgggga ccagttctcc   1440

agtgagtcct ccttggaagc ctatgctcgc tgcctgcgga tgggctgtcg ctgcattgag   1500

ttggactgct gggacggccc ggatgggatg ccagttattt accatgggca cacccttacc   1560

accaagatca agttctcaga tgtcctgcac accatcaagg agcatgcctt tgtggcctca   1620

gagtacccag tcatcctgtc cattgaggac cactgcagca ttgcccagca gagaaacatg   1680

gcccaatact tcaagaaggt gctgggggac acactcctca ccaagcccgt ggagatctct   1740

gccgacgggc tcccctcacc caaccagctt aagaggaaga tcctcatcaa gcacaagaag   1800

ctggctgagg gcagtgccta cgaggaggtg cctacatcca tgatgtactc tgagaacgac   1860

atcagcaact ctatcaagaa tggcatcctc tacctggagg accctgtgaa ccacgaatgg   1920

tatccccact actttgttct gaccagcagc aagatctact actctgagga gaccagcagt   1980

gaccagggca acgaggatga ggaggagccc aaggaggtca gcagcagcac agagctgcac   2040

tccaatgaga agtggttcca tgggaagcta ggggcagggc gtgacgggcg tcacatcgct   2100

gagcgcctgc ttactgagta ctgcatcgag accggagccc ctgacggctc cttcctcgtg   2160

cgagagagtg agaccttcgt gggcgactac acgctctctt tctggcggaa cgggaaagtc   2220

cagcactgcc gtatccactc ccggcaagat gctgggaccc ccaagttctt cttgacagac   2280

aacctcgtct ttgactccct ctatgacctc atcacgcact accagcaggt gcccctgcgc   2340

tgtaatgagt ttgagatgcg actttcagag cctgtcccac agaccaacgc ccacgagagc   2400

aaagagtggt accacgcgag cctgaccaga gcacaggctg agcacatgct aatgcgcgtc   2460

cctcgtgatg gggccttcct ggtgcggaag cggaatgaac ccaactcata tgccatctct   2520

ttccgggctg agggcaagat caagcattgc cgtgtccagc aagagggcca gacagtgatg   2580

ctagggaact cggagttcga cagccttgtt gacctcatca gctactatga gaaacacccg   2640

ctataccgca agatgaagct gcgctatccc atcaacgagg aggcactgga gaagattggc   2700

acagctgagc ctgactacgg ggccctgtat gagggacgca accctggctt ctatgtagag   2760

gcaaacccta tgccaacttt caagtgtgca gtcaaagccc tctttgacta caaggcccag   2820

agggaggacg agctgacctt catcaagagc gccatcatcc agaatgtgga gaagcaagag   2880

ggaggctggt ggcgagggga ctacggaggg aagaagcagc tgtggttccc atcaaactac   2940

gtggaagaga tggtcaaccc cgtggccctg gagccggaga gggagcactt ggacgagaac   3000

agccccctag gggacttgct gcggggggtc ttggatgtgc cggcttgtca gattgccatc   3060

cgtcctgagg gcaagaacaa ccggctcttc gtcttctcca tcagcatggc gtcggtggcc   3120

cactggtccc tggatgttgc tgccgactca caggaggagc tgcaggactg ggtgaaaaag   3180

atccgtgaag tggcccagac agcagacgcc aggctcactg aagggaagat aatggaacgg   3240

aggaagaaga ttgccctgga gctctctgaa cttgtcgtct actgccggcc tgttcccttt   3300

gatgaagaga agattggcac agaacgtgct tgctaccggg acatgtcatc cttcccggaa   3360

accaaggctg agaaatacgt gaacaaggcc aaaggcaaga agttccttca gtacaatcga   3420

ctgcagctct cccgcatcta ccccaagggc cagcgactgg attcctccaa ctacgatcct   3480

ttgcccatgt ggatctgtgg cagtcagctt gtggccctca acttccagac ccctgacaag   3540

cctatgcaga tgaaccaggc cctcttcatg acgggcaggc actgtggcta cgtgctgcag   3600

ccaagcacca tgcgggatga ggccttcgac ccctttgaca agagcagcct ccgcgggctg   3660

gagccatgtg ccatctctat tgaggtgctg ggggcccgac atctgccaaa gaatggccga   3720

ggcattgtgt gtccttttgt ggagattgag gtggctggag ctgagtatga cagcaccaag   3780

cagaagacag agtttgtggt ggacaatgga ctcaaccctg tatggccagc caagcccttc   3840

cacttccaga tcagtaaccc tgaatttgcc tttctgcgct tcgtggtgta tgaggaagac   3900

atgtttagtg accagaattt cctggctcag gctactttcc cagtaaaagg cctgaagaca   3960

ggatacagag cagtgccttt gaagaacaac tacagtgagg acctggagtt ggcctccctg   4020

ctgatcaaga ttgacatttt ccctgccaag caggagaatg gtgacctcag tcccttcagt   4080

ggtacgtccc tgcgggagcg gggctcagat gcctcaggcc agctgtttca tggccgagcc   4140

cgggaaggct cctttgaatc ccgctaccag cagccgtttg aggacttccg catctcccag   4200

gagcatctcg cagaccattt tgacagtcga gaacgaaggg ccccaagaag gactcgggtc   4260

aatggagaca accgcctcta gttgtacccc agcctcgttg gagagcagca ggtgctgtgc   4320

gccttgtaga atgccgcgaa ctgggttctt tggaagcagc cccctgtggc ggccttccgg   4380

gtctcgcagc ctgaagcctg gattccagca gtgaatgcta gacagaaacc aagccattaa   4440

tgagatgtta ttactgtttt gggcctccat gccccagctc tggatgaagg caaaaactgt   4500

actgtgtttc gcattaagca cacacatctg gccctgactt ctggagatgg atccttccat   4560

cttgtggggc caggaccatg gccgaagccc cttggagaga gaggctgcct cagccagtgg   4620

cacaggagac tccaaggagc tactgacatt cctaagagtg gaggaggagg aggagccttg   4680

ctgggccagg gaaacaaagt ttacattgtc ctgtagcttt aaaaccacag ctgggcaggg   4740

tgagaagcta gatgcccctg cagtttggcc ctggagccag ggcagaggaa tgtagggcct   4800

gcatggagaa gggttctgcc ctgcctgagg aggaggacac agcacaaggg cacattgccc   4860

atggctggga acatgaccca gcctgaaaga tacaggggat catgttaaaa atagcagtat   4920

tatttttcgt ctcaatggta ttgtaactaa gttatttact cctcctgctc ctcacccctg   4980

tagggaaacc ttggagagga gagtggcagg tgggctgcct gctgtgttaa gaggacttag   5040

tttgtgatgt aaggcactgt caggaatggg gggcgggcca gggtgggaag agaagaaata   5100

gcagagccta ttttggtgag gttttttgtt tttaagtcaa agaagactca gtatgctttc   5160

cctgaggaat gaaaaaggga ttgaggagtt gcctgactcc tgggtgggtg gggtacaggc   5220

agttaggtgc tgaatgaagc tgccatcctt gctgcagctt ctaactggta aaaagatcca   5280

gggatggaga tgggaaggtt agaaaggcag ccctcacctc tgaggacaga ggccggggtc   5340

caggcccgtg ggcgcaaagg tgcctcatag catagccagc attcagcaca cacaaaccta   5400

ctgcccacat ttgggctcag ggttggccat ttgctagttc tgctgccctc ttaagatctg   5460

actgccaaat aaatcatcct catgtccttt ttcctttgac ttgtatgctc tttcgggggc   5520

tcaggaaagc ctgttgcatg ggacatgctc actagaaaca gtcgccagat gattattctg   5580

cagtagaagc aggtaggaaa tttctggaaa tttctcaggt taagcagcaa gagctgtaac   5640

ccctcctctg ggctaacagg agttgtgggt ccactctctc ctgcccaccc tctgagggtg   5700

tgtctgagca gagtacatcc tgcctgggtt ctttgtggcc agccagtttt ggtggtgagc   5760

tggaaacaac cagagcccct ttccagttcc acagaaacct ctcctttcaa aaatgttgca   5820

ttcagttcgt taacactgcc aggtgccatt ctgattgcct ctaggacttg gcagctgaaa   5880

tctctgggcc ctttcaacac agttgaaagg cccttctctt cctgaagctc tgtttccata   5940

gttggctgtg ctgggatgga acaaaaatga cgccacacaa aaaatttaag atagatccgg   6000

ttccgtggat gacatgaact gatgatagcc agtatcaaac agcgatagtg              6050


<210>  10104
<211>  1291
<212>  PRT
<213>  Homo sapiens

<400>  10104

Met Ala Gly Ala Ala Ser Pro Cys Ala Asn Gly Cys Gly Pro Gly Ala 
1               5                   10                  15


Pro Ser Asp Ala Glu Val Leu His Leu Cys Arg Ser Leu Glu Val Gly 
            20                  25                  30


Thr Val Met Thr Leu Phe Tyr Ser Lys Lys Ser Gln Arg Pro Glu Arg 
        35                  40                  45


Lys Thr Phe Gln Val Lys Leu Glu Thr Arg Gln Ile Thr Trp Ser Arg 
    50                  55                  60


Gly Ala Asp Lys Ile Glu Gly Ala Ile Asp Ile Arg Glu Ile Lys Glu 
65                  70                  75                  80


Ile Arg Pro Gly Lys Thr Ser Arg Asp Phe Asp Arg Tyr Gln Glu Asp 
                85                  90                  95


Pro Ala Phe Arg Pro Asp Gln Ser His Cys Phe Val Ile Leu Tyr Gly 
            100                 105                 110


Met Glu Phe Arg Leu Lys Thr Leu Ser Leu Gln Ala Thr Ser Glu Asp 
        115                 120                 125


Glu Val Asn Met Trp Ile Lys Gly Leu Thr Trp Leu Met Glu Asp Thr 
    130                 135                 140


Leu Gln Ala Pro Thr Pro Leu Gln Ile Glu Arg Trp Leu Arg Lys Gln 
145                 150                 155                 160


Phe Tyr Ser Val Asp Arg Asn Arg Glu Asp Arg Ile Ser Ala Lys Asp 
                165                 170                 175


Leu Lys Asn Met Leu Ser Gln Val Asn Tyr Arg Val Pro Asn Met Arg 
            180                 185                 190


Phe Leu Arg Glu Arg Leu Thr Asp Leu Glu Gln Arg Ser Gly Asp Ile 
        195                 200                 205


Thr Tyr Gly Gln Phe Ala Gln Leu Tyr Arg Ser Leu Met Tyr Ser Ala 
    210                 215                 220


Gln Lys Thr Met Asp Leu Pro Phe Leu Glu Ala Ser Thr Leu Arg Ala 
225                 230                 235                 240


Gly Glu Arg Pro Glu Leu Cys Arg Val Ser Leu Pro Glu Phe Gln Gln 
                245                 250                 255


Phe Leu Leu Asp Tyr Gln Gly Glu Leu Trp Ala Val Asp Arg Leu Gln 
            260                 265                 270


Val Gln Glu Phe Met Leu Ser Phe Leu Arg Asp Pro Leu Arg Glu Ile 
        275                 280                 285


Glu Glu Pro Tyr Phe Phe Leu Asp Glu Phe Val Thr Phe Leu Phe Ser 
    290                 295                 300


Lys Glu Asn Ser Val Trp Asn Ser Gln Leu Asp Ala Val Cys Pro Asp 
305                 310                 315                 320


Thr Met Asn Asn Pro Leu Ser His Tyr Trp Ile Ser Ser Ser His Asn 
                325                 330                 335


Thr Tyr Leu Thr Gly Asp Gln Phe Ser Ser Glu Ser Ser Leu Glu Ala 
            340                 345                 350


Tyr Ala Arg Cys Leu Arg Met Gly Cys Arg Cys Ile Glu Leu Asp Cys 
        355                 360                 365


Trp Asp Gly Pro Asp Gly Met Pro Val Ile Tyr His Gly His Thr Leu 
    370                 375                 380


Thr Thr Lys Ile Lys Phe Ser Asp Val Leu His Thr Ile Lys Glu His 
385                 390                 395                 400


Ala Phe Val Ala Ser Glu Tyr Pro Val Ile Leu Ser Ile Glu Asp His 
                405                 410                 415


Cys Ser Ile Ala Gln Gln Arg Asn Met Ala Gln Tyr Phe Lys Lys Val 
            420                 425                 430


Leu Gly Asp Thr Leu Leu Thr Lys Pro Val Glu Ile Ser Ala Asp Gly 
        435                 440                 445


Leu Pro Ser Pro Asn Gln Leu Lys Arg Lys Ile Leu Ile Lys His Lys 
    450                 455                 460


Lys Leu Ala Glu Gly Ser Ala Tyr Glu Glu Val Pro Thr Ser Met Met 
465                 470                 475                 480


Tyr Ser Glu Asn Asp Ile Ser Asn Ser Ile Lys Asn Gly Ile Leu Tyr 
                485                 490                 495


Leu Glu Asp Pro Val Asn His Glu Trp Tyr Pro His Tyr Phe Val Leu 
            500                 505                 510


Thr Ser Ser Lys Ile Tyr Tyr Ser Glu Glu Thr Ser Ser Asp Gln Gly 
        515                 520                 525


Asn Glu Asp Glu Glu Glu Pro Lys Glu Val Ser Ser Ser Thr Glu Leu 
    530                 535                 540


His Ser Asn Glu Lys Trp Phe His Gly Lys Leu Gly Ala Gly Arg Asp 
545                 550                 555                 560


Gly Arg His Ile Ala Glu Arg Leu Leu Thr Glu Tyr Cys Ile Glu Thr 
                565                 570                 575


Gly Ala Pro Asp Gly Ser Phe Leu Val Arg Glu Ser Glu Thr Phe Val 
            580                 585                 590


Gly Asp Tyr Thr Leu Ser Phe Trp Arg Asn Gly Lys Val Gln His Cys 
        595                 600                 605


Arg Ile His Ser Arg Gln Asp Ala Gly Thr Pro Lys Phe Phe Leu Thr 
    610                 615                 620


Asp Asn Leu Val Phe Asp Ser Leu Tyr Asp Leu Ile Thr His Tyr Gln 
625                 630                 635                 640


Gln Val Pro Leu Arg Cys Asn Glu Phe Glu Met Arg Leu Ser Glu Pro 
                645                 650                 655


Val Pro Gln Thr Asn Ala His Glu Ser Lys Glu Trp Tyr His Ala Ser 
            660                 665                 670


Leu Thr Arg Ala Gln Ala Glu His Met Leu Met Arg Val Pro Arg Asp 
        675                 680                 685


Gly Ala Phe Leu Val Arg Lys Arg Asn Glu Pro Asn Ser Tyr Ala Ile 
    690                 695                 700


Ser Phe Arg Ala Glu Gly Lys Ile Lys His Cys Arg Val Gln Gln Glu 
705                 710                 715                 720


Gly Gln Thr Val Met Leu Gly Asn Ser Glu Phe Asp Ser Leu Val Asp 
                725                 730                 735


Leu Ile Ser Tyr Tyr Glu Lys His Pro Leu Tyr Arg Lys Met Lys Leu 
            740                 745                 750


Arg Tyr Pro Ile Asn Glu Glu Ala Leu Glu Lys Ile Gly Thr Ala Glu 
        755                 760                 765


Pro Asp Tyr Gly Ala Leu Tyr Glu Gly Arg Asn Pro Gly Phe Tyr Val 
    770                 775                 780


Glu Ala Asn Pro Met Pro Thr Phe Lys Cys Ala Val Lys Ala Leu Phe 
785                 790                 795                 800


Asp Tyr Lys Ala Gln Arg Glu Asp Glu Leu Thr Phe Ile Lys Ser Ala 
                805                 810                 815


Ile Ile Gln Asn Val Glu Lys Gln Glu Gly Gly Trp Trp Arg Gly Asp 
            820                 825                 830


Tyr Gly Gly Lys Lys Gln Leu Trp Phe Pro Ser Asn Tyr Val Glu Glu 
        835                 840                 845


Met Val Asn Pro Val Ala Leu Glu Pro Glu Arg Glu His Leu Asp Glu 
    850                 855                 860


Asn Ser Pro Leu Gly Asp Leu Leu Arg Gly Val Leu Asp Val Pro Ala 
865                 870                 875                 880


Cys Gln Ile Ala Ile Arg Pro Glu Gly Lys Asn Asn Arg Leu Phe Val 
                885                 890                 895


Phe Ser Ile Ser Met Ala Ser Val Ala His Trp Ser Leu Asp Val Ala 
            900                 905                 910


Ala Asp Ser Gln Glu Glu Leu Gln Asp Trp Val Lys Lys Ile Arg Glu 
        915                 920                 925


Val Ala Gln Thr Ala Asp Ala Arg Leu Thr Glu Gly Lys Ile Met Glu 
    930                 935                 940


Arg Arg Lys Lys Ile Ala Leu Glu Leu Ser Glu Leu Val Val Tyr Cys 
945                 950                 955                 960


Arg Pro Val Pro Phe Asp Glu Glu Lys Ile Gly Thr Glu Arg Ala Cys 
                965                 970                 975


Tyr Arg Asp Met Ser Ser Phe Pro Glu Thr Lys Ala Glu Lys Tyr Val 
            980                 985                 990


Asn Lys Ala Lys Gly Lys Lys Phe Leu Gln Tyr Asn Arg Leu Gln Leu 
        995                 1000                1005


Ser Arg Ile Tyr Pro Lys Gly Gln Arg Leu Asp Ser Ser Asn Tyr Asp 
    1010                1015                1020


Pro Leu Pro Met Trp Ile Cys Gly Ser Gln Leu Val Ala Leu Asn Phe 
1025                1030                1035                1040


Gln Thr Pro Asp Lys Pro Met Gln Met Asn Gln Ala Leu Phe Met Thr 
                1045                1050                1055


Gly Arg His Cys Gly Tyr Val Leu Gln Pro Ser Thr Met Arg Asp Glu 
            1060                1065                1070


Ala Phe Asp Pro Phe Asp Lys Ser Ser Leu Arg Gly Leu Glu Pro Cys 
        1075                1080                1085


Ala Ile Ser Ile Glu Val Leu Gly Ala Arg His Leu Pro Lys Asn Gly 
    1090                1095                1100


Arg Gly Ile Val Cys Pro Phe Val Glu Ile Glu Val Ala Gly Ala Glu 
1105                1110                1115                1120


Tyr Asp Ser Thr Lys Gln Lys Thr Glu Phe Val Val Asp Asn Gly Leu 
                1125                1130                1135


Asn Pro Val Trp Pro Ala Lys Pro Phe His Phe Gln Ile Ser Asn Pro 
            1140                1145                1150


Glu Phe Ala Phe Leu Arg Phe Val Val Tyr Glu Glu Asp Met Phe Ser 
        1155                1160                1165


Asp Gln Asn Phe Leu Ala Gln Ala Thr Phe Pro Val Lys Gly Leu Lys 
    1170                1175                1180


Thr Gly Tyr Arg Ala Val Pro Leu Lys Asn Asn Tyr Ser Glu Asp Leu 
1185                1190                1195                1200


Glu Leu Ala Ser Leu Leu Ile Lys Ile Asp Ile Phe Pro Ala Lys Gln 
                1205                1210                1215


Glu Asn Gly Asp Leu Ser Pro Phe Ser Gly Thr Ser Leu Arg Glu Arg 
            1220                1225                1230


Gly Ser Asp Ala Ser Gly Gln Leu Phe His Gly Arg Ala Arg Glu Gly 
        1235                1240                1245


Ser Phe Glu Ser Arg Tyr Gln Gln Pro Phe Glu Asp Phe Arg Ile Ser 
    1250                1255                1260


Gln Glu His Leu Ala Asp His Phe Asp Ser Arg Glu Arg Arg Ala Pro 
1265                1270                1275                1280


Arg Arg Thr Arg Val Asn Gly Asp Asn Arg Leu 
                1285                1290


<210>  10105
<211>  1052
<212>  DNA
<213>  Homo sapiens

<400>  10105
tagttgtacc ccagcctcgt tggagagcag caggtgctgt gcgccttgta gaatgccgcg     60

aactgggttc tttggaagca gccccctgtg gcggccttcc gggtctcgca gcctgaagcc    120

tggattccag cagtgaatgc tagacagaaa ccaagccatt aatgagatgt tattactgtt    180

ttgggcctcc atgccccagc tctggatgaa ggcaaaaact gtactgtgtt tcgcattaag    240

cacacacatc tggccctgac ttctggagat ggatccttcc atcttgtggg gccaggacca    300

tggccgaagc agccctcacc tctgaggaca gaggccgggg tccaggcccg tgggcgcaaa    360

ggtgcctcat agcatagcca gcattcagca cacacaaacc tactgcccac atttgggctc    420

agggttggcc atttgctagt tctgctgccc tcttaagatc tgactgccaa ataaatcatc    480

ctcatgtcct ttttcctttg acttgtatgc tctttcgggg gctcaggaaa gcctgttgca    540

tgggacatgc tcactagaaa cagtcgccag atgattattc tgcagtagaa gcaggtagga    600

aatttctgga aatttctcag gttaagcagc aagagctgta acccctcctc tgggctaaca    660

ggagttgtgg gtccactctc tcctgcccac cctctgaggg tgtgtctgag cagagtacat    720

cctgcctggg ttctttgtgg ccagccagtt ttggtggtga gctggaaaca accagagccc    780

ctttccagtt ccacagaaac ctctcctttc aaaaatgttg cattcagttc gttaacactg    840

ccaggtgcca ttctgattgc ctctaggact tggcagctga aatctctggg ccctttcaac    900

acagttgaaa ggcccttctc ttcctgaagc tctgtttcca tagttggctg tgctgggatg    960

gaacaaaaat gacgccacac aaaaaattta agatagatcc ggttccgtgg atgacatgaa   1020

ctgatgatag ccagtatcaa acagcgatag tg                                 1052


<210>  10106
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  10106

Met Leu Asp Arg Asn Gln Ala Ile Asn Glu Met Leu Leu Leu Phe Trp 
1               5                   10                  15


Ala Ser Met Pro Gln Leu Trp Met Lys Ala Lys Thr Val Leu Cys Phe 
            20                  25                  30


Ala Leu Ser Thr His Ile Trp Pro 
        35                  40


<210>  10107
<211>  9763
<212>  DNA
<213>  Homo sapiens

<400>  10107
attgaatagg gaaaacctgc tttctgcaaa caactgaaaa agctgcattt agaaactgtt     60

tctttggccc tcatcgagaa gctggaactt gtattgttag gccccttatg ggacaagctc    120

tcaactgctg atcacccagt gattgtcacc atggccagca agaggaaatc caccacacca    180

tgcatgatcc cagtgaagac tgtggtgttg caagatgcca gcatggaggc ccagcccgct    240

gagaccttgc ctgaaggacc ccagcaggat ctgcccccag aagcatctgc tgccagcagt    300

gaggcagcac agaaccccag cagtactgat ggctctacac tggccaatgg gcatcggagc    360

actttagatg gctatttata ttcctgtaaa tactgcgatt tcagatccca tgacatgacc    420

caatttgtgg gacatatgaa ctcagagcac acagacttta ataaagaccc aacctttgta    480

tgcagtgggt gcagttttct ggcaaaaacc cctgaggggc tttccttgca caatgccaca    540

tgtcactccg gggaagccag ctttgtgtgg aacgtggcca agccagacaa tcatgtggtt    600

gtggagcaga gcatccctga gagcaccagc actcctgacc tagcgggtga gcccagtgct    660

gaaggggctg atggacaggc agaaatcatc attaccaaaa ctccaatcat gaagataatg    720

aaaggcaaag ctgaagccaa aaaaattcat acactcaagg agaatgtccc tagccagcct    780

gtgggtgagg ccttaccaaa gctgtcgact ggagaaatgg aggtgagaga gggggaccat    840

tccttcatca atggggcagt tccagtcagc caggcatctg ccagctctgc aaaaaacccc    900

catgccgcca acgggcccct gataggaaca gtgccagttt tgccagctgg catagcacag    960

ttcctctccc tccagcagca gcccccagtg catgcccaac accatgtcca ccagccactg   1020

cccacggcca aggcccttcc caaagtgatg atccccctga gcagcattcc aacgtacaat   1080

gcagccatgg actctaacag cttcctgaag aactccttcc acaagttccc ctaccccacc   1140

aaagccgagc tctgctattt gactgtggtg accaagtatc cagaagaaca gctcaagatc   1200

tggttcacag cccaaaggct gaagcagggg atcagctggt cccctgagga gattgaggat   1260

gcccggaaaa agatgttcaa tacagtcatc cagtctgtgc ctcagcccac aattacggtt   1320

ctaaataccc cactcgtcgc cagtgctggc aatgtccagc atctcatcca ggccgctctt   1380

ccaggtcacg ttgtggggca gccagagggt acaggagggg gacttctggt cactcagcca   1440

ttgatggcca atgggttgca agcaacaagt tcccctctcc ccctcacggt gacatccgtc   1500

cccaagcagc caggtgtggc acccattaac actgtgtgtt caaatacaac gtcagctgtg   1560

aaggtggtca atgcggccca gtcgctcctc acggcctgcc ccagcataac ctcccaagcc   1620

ttccttgatg ctagcatcta caaaaataag aaatctcatg aacagctgtc agctctgaaa   1680

gggagcttct gtcggaacca gttcccaggg cagagcgaag ttgaacatct cacaaaagtg   1740

acgggcctca gtaccagaga ggtgcggaaa tggttcagtg atcgtagata ccactgccgg   1800

aacttgaagg gctccagagc gatgatacct ggagatcaca gttccatcat cattgactct   1860

gtgccagagg tgtccttctc cccatcgtcc aaggtccctg aggtaacctg cattccgaca   1920

acagccacac tagcaaccca cccttctgcc aaacgacaat cttggcacca gactcctgac   1980

ttcacaccaa ccaaatacaa ggagagagcc cctgagcagc tcagagccct ggagagcagt   2040

tttgcacaaa accctcttcc tcttgatgag gaactggacc gcctgagaag tgaaaccaaa   2100

atgacccgac gagaaattga tagctggttt tcagagagac ggaaaaaagt gaatgctgag   2160

gagaccaaga aggctgagga gaatgcctct caggaggaag aggaggctgc tgaggatgag   2220

ggtggagaag aggatttggc cagtgagcta agggtctctg gtgaaaatgg ctctctggaa   2280

atgcccagca gccatatctt ggcagagcgc aaagtcagcc ccattaaaat caacctgaag   2340

aacctgaggg tcactgaagc caatggcagg aacgagattc cagggctggg tgcctgtgac   2400

cctgaggatg atgagtcaaa caaactggca gagcagctcc caggcaaagt gagctgcaaa   2460

aagactgccc agcagcggca cttgctgcgg cagctctttg tccagacaca gtggccaagc   2520

aaccaggact atgactccat catggcccag acgggtctgc cacggccaga ggtggtgcgc   2580

tggtttggag atagcaggta cgcactgaag aacggccaac tcaaatggta cgaagactat   2640

aagcgaggca acttcccacc agggctactg gtcattgccc ctggcaaccg ggagctcctg   2700

caggactatt acatgacaca caagatgctg tatgaagagg acctgcagaa cctctgtgac   2760

aagacccaga tgagctccca gcaggtcaag cagtggtttg ctgagaaaat gggggaggag   2820

accagagccg tggcagacac aggcagtgag gaccagggcc ctggtactgg tgagctcaca   2880

gcagttcaca aagggatggg tgacacctat tcagaggtgt ctgagaacag tgagtcgtgg   2940

gagccccgtg tccctgaggc cagctcagag ccctttgaca catcgagtcc ccaggctgga   3000

cgtcagctcg aaacagactg aatttgatct gattaatgtg aaggactggc cagtctggga   3060

aaccgcctgc cacgtggaag agccaaaccc gactctctgc tgccacatgc cgttcccatg   3120

cccggctgct gggcacctgg gagagcttcc agaatcctcg cagacagccc agagcctgcc   3180

gctaccctcg gcctgcccac caccaagcaa gcagcaagca agatggggtt ctcatcagtt   3240

cttcctccca caatgtagga cctttccttt accttccaat ggataaaata gttcagagtt   3300

catagtcata ttcatagaca cagaatcaag cttttaacat atacatccac ctctatatgt   3360

taaataaaac atcagattat caacactgtc attacgtaga aactttggtt agccaagcag   3420

tgcattgtca gttacgtcat ctctaaaaat gacctgtgtc tgttctctgg ggattgctgg   3480

gtcacaggtg cccctcacct tccacagtca ggcagggaag ttataggcac aaagctacgt   3540

ctggaacccc tttgtgcccc ctttgtgttc ctcaaggaag cagtaccttt gaagagatct   3600

ctgctgcatt aagtgatgac cggctacgtt tcatgtcagg cttgctttgc cttgtgggct   3660

actcagtgca gaacctgctg taaccctcag ttcaaaaaat ggactggcaa tgtgattagc   3720

gttggatgct ttaccattct ctttagttgt taccgtaatt ctgctttttc atgggagttt   3780

gaatcatgga ccataacttt tcagttatca gatcaactaa agaaacattt gttgttaagc   3840

ctaatgtgct gacctatgtg cctgcatttt ttttttaatc tagacatgtt tggagtgaga   3900

gaaagatgga aaaaagacat ggggtaggga cgtaagtgga aatctatagc cacagcctga   3960

agctttgacc actgcggttt tcagagccct ttctccacac tcatttcaga gcctcctatg   4020

gtttgggaag gaataacaca ctggcccatt agtaagggtg aaggctggag ggatttgttg   4080

acttcttgga attatcagag gtagggtggt ctttagcaca aagacttgca tgcagagatc   4140

cctggcagaa cacccagagt gcccgtggct cccaccccag ggtctggccg gtgtgctgga   4200

tgcatgccca agggtgctgg gcatcactgg tccttgtgag gatgctttta aagttttata   4260

tttatgtccc caaacttgga aacaagaact ctactttagc ctaaccctca tgtccttttt   4320

tgaattgaga aaattacagg aaatggtgcc tttgaaaatt agaaaacttg cttacagagc   4380

tgttctaaat ggtaaatcct caatttcccc aagaccggtt gctctgagag tagctggtaa   4440

agaggggcga actaaagacc tgtccacctg tagctccgct catttcttag aaaccacctg   4500

cttcccagag tgccaagcca caagtaccag gcttcgtggg cacagacacc tcctgggctg   4560

ggcagagtga cagtgctaga agaccccaga gagagggcaa gggctttggg caagaagcac   4620

tggtggtgtt ttagggaccg tccttctccc ctacccaggg aactggacct ggcagggcac   4680

cgtgctcatg tggctccaag gacaagcatg gcggtggccc cttctgcctt ccaggagagg   4740

tcttgctttt gaaaccaaaa tcatgttctt ctaaagtgtc atcttctgcc ctccctgtcc   4800

caatagggac cacatcttat ttgtctcaaa cagggacttg tgagtacttg gcaagttttg   4860

cagcctattt ttgtattctt aatttgggga gtaaagatgt ttggtctcaa aaacctttga   4920

ggaattgcca agaatggcga gtgattgctt tccttcagag aacagacact tggaatttct   4980

ccttttagtg tttatatacg tgcagattaa tttatatata tatatataca cacacacata   5040

tacagtataa atactcattt gattctcgta aaacgcgcat ctggcgtgtg cagttgagaa   5100

acttggtggc acatgggtgt tgggggagta gcctgtgttg gagggacacc agtgcactag   5160

gcagctgggg cggcccaggc tgaagccatc tccgggtgtc tgagaaacca cccagtgcct   5220

cacctccaga tcctgctggc atcacctcca gagccctgca tgcactggct gaagagttgg   5280

tctgtggaga ggattttctt ggttacttgt attcacggtt aatttacaac ccaaacagca   5340

aaacacagtt ggtggacaag ttcatgcagg acctacagtg acccagccat gggcactagc   5400

tcatctttca ggtggaaaag tacagtgctg cctgccctgg tatgtttttc ttatagatgt   5460

tagccctgcc caacagccag ggctacacta caaaaggcaa gaatgcccat gtaaggagcc   5520

cagcagtctg gacagatcct tcttcctctg ctgttggatg agagtgagtg agtatgctct   5580

ggaccttatc cttgaaagat gatcaaaagc gatgatgagg gaggcagtca tcacgcaggt   5640

gcttaaaggg acattgtagg aggtactcaa gggtttgggg gcaaaaccct gaatccagcc   5700

agtcgtgcac agagacacac ccacactagc ccagtggcag tgggggatgt gggatggcag   5760

cagccaggta tgtagccctg tcacaggaca gctcactgtg gttttgcaca ctgcctaagg   5820

gttaaattgt gttgttgcct tcagtagaag gcatttgtgg gctgcagagt tgagagttgg   5880

gtgaggttag tctctcctga agaaaaagcc tataaaaagt ggctaatctt atcccttttc   5940

tctgtatgca gttggactcg tcagagatag taaaatcatc ttttagtgtt tttttgttgc   6000

tgatgtcttg tacccatttg ttttttacat ggggttgtag atcgagttct caaaggtgaa   6060

accagatgat cattctgata aaggaaattt aaatttgata catatgcttt gtatattttg   6120

attacttgtt ttcgtttttg actataaagg agctttttta ttttgggagg ggaggagtgt   6180

catttttgag aatcttgggt tcctgaaaaa gaacgcccta gttggatggc ttgccagggc   6240

cttggggttt ggtagtgatt gtacaactta aagctccttt ctcttggctg agtgacaggt   6300

ggctgttcag gtggaccaaa gcaccttgac acaaggactc cacactgtgc tctctagtag   6360

cacaaggagg aagttggaca gaacattggg tagtgccttg cgggctcaca catgtactag   6420

tggtctcatc tccagctagc cttgggaggc cgtcccacca ggaaatctct ctattccgta   6480

gcctgagatg tgcccttgtg ggttttatcc tgctcagtca gtggcctagg ggcaggtcct   6540

gtgttctctc cctctctctc ctggctctgg gacatctgtc cctggctgcc tttcatggag   6600

gaaggacact ggcctttctg gttggatgct gtgtggatgc tctctgcttg agcctcgtgg   6660

tctcttgtct ctttttggac caatatcctc agattggtgc agctttttca gttcagatat   6720

cacaccccaa gtggataaag gcaacttgca ggagaggaga gccagccaag aagaaaattt   6780

taaaaccaaa cctcgtttag gattttccta aagtcatctt ctcttttttc ttgctcagag   6840

tttacctggg agatttcacc agtttgactc accatttgca gatgtgcttt tgtattaaat   6900

ttaaattttc acatatcaca tccattctca aggtagttat atgctggaga agaaaaatcc   6960

tctagacaca tgaaggccca catagtcaag tcttccaggg caaagccagc agcccaccca   7020

ggtcaggtag ccagcagggc tcagttcccc tcactccaga cacggaccct cctcttcagg   7080

gtctcttgac ccagcttcct tctctccttt tacctgagag cacagacctc tctcagccag   7140

cctgcccaga ccacgggggg ctactcccat gtagtttggg gagcacttga tctcagaaaa   7200

gctccattgt ctgagcaaat gggcagttgt ggagctcaag cctttctcct gtgctcaagt   7260

cccttcccca agcaaggctt caacctcatc tacccaccat gtagttttct ctggccattt   7320

aagtggggcg gcagggacat ggttgggcca tgccacacca gggctggtga ggcaaccagt   7380

tttgattttg acagagtggc tggaggaaaa gtggcaatca aggtgctgct tggtttgctc   7440

tgagtgcaaa tggaaccaac aggtttctgc tgcaatctgt gtgttcccag tgccaggtca   7500

caccaggagg ggtggggcag ggctaaccaa gtggtctctg aactcaccga gcgtctgcac   7560

ttggttgtga agttaatggg agtacagaga gcgtctggcc ttggagaggg gttgagagcc   7620

tcctttttgg ttcttcattc ctgagctctt gcctgcccac aaatctgacc tctttgaatg   7680

gggacgcagt ccttcaacag agaagtttct atggcaaaga agtttctatt tagctctaga   7740

tccagcagag tcatccattc taactgccct gaagtctaga gcaggggagg gaacccagag   7800

gctggggatg agactaggca gaccctggtt accatatgga caaggacagg ggaaagcacc   7860

cccttcctca atttctgaaa gttctatctt tgggttcgca ggactttgag gatgataaag   7920

aacatatagg tactagcttg ttgttgctgg tccaaagctt ccacagccct gagaatttgg   7980

ctttcgtggc tgctctggca gctgagcgaa gggaggaagg cagccgctct ggtggggact   8040

ctaggcacct tccctgctgt ccacttggat aggcggtgag ccccagggta ctgagaggag   8100

cctgagcatt tacctgccat tagtgcctct tccttcagga gactggcttg aaacgtgtgt   8160

tcatgtgcgc gtgcacacac acacatgagc acctgtatgt gttaatgaat agtttttctt   8220

ggttaatgct ttttaacttc tgttcctttc cgtaagtgga tgattcaaaa ttaacgtgac   8280

ttggctgggc gcagtggctc acacctgtaa tcccagcact ttgggaggcc aagggaggcg   8340

gatcacctga ggtcaggagt tcgagaccag cctgatcggc atggtgaaac cccgtttcta   8400

ctaaaaatac aaaaattagc cgggcgtggt ggtgcgcgcc tgtaatccca gctactcagg   8460

aggctgagga aggagaatca cttgaacccg ggaggtggag gttgcagtga gctgagatcg   8520

tgccactgca ctccagcctg ggcgacagag cgaaactccg tctcaaaaaa aaaaaaaaaa   8580

cttaatgtga ctggagttaa aagtgaaatg tcaggttgtt tagtcactga atagagagct   8640

acaagtgctt ggtctttccc aagaatcaaa cctgagtaga aatacattta aaagaaaaat   8700

ctacatggta cctatgaatc ctgtaatttg tttagggaga tcttgtcact catccctggt   8760

tcctgcccat actgtttggt ctcgttcttg cagtttgctt ggaacagggc cagagcccca   8820

catgagattg tcagcaggag tgaggagcgc cagtccctac tcctcagcag ggacccagca   8880

cagcaatccg gttgttctcg gttagactgg gtcggggcca ggggagaagc agtcacccct   8940

gtgtagaggg ttcccgctgt gcttctgagc agttgctttg ttcagaagtg ttaggagggt   9000

cagattgtgc cataattgtt attaaagaga aaacacgccc accttccttt ctcccctgct   9060

ggccattgtt cattgagttt tactgagggc agcctttgtg gaagtcaggg aggttgccaa   9120

aggcctgtag atgcctcctg acaaggtctt gattcctggt tttctagcac ccatttgcat   9180

tttggtcttc agcacaaagc cttgttccct gtggccggac ttctgggcaa taagactggg   9240

gagtgactgt tgagcagtct gctgtcagga gagatggctg aaaaggtgat catcttggtg   9300

ctaaacaagt aagaggcaac tgccctgttt ttgtttgttt tgaggcacaa tgaaacttta   9360

gccaaactct gcaagagggt cccatctcct gccatggcca ggtgtgagag accaaaccga   9420

gaaaacagca tactctatca cttaagcctt gggtagaatg ggaattcttt accctgggta   9480

aacgttttaa caaaaaaatg gaacttaact tcggtttgga ctgtggtcgt gctgaggcag   9540

gagtggggtt gccctcttgg ggctgaatct ccaggcctca cgaggtcccc tgtggggatg   9600

ctgctatttc taagatgcaa attgcacatt tcctagattt tgtatctgtg gatttggata   9660

agggagggga acacggacaa attgcttgta caatttgaaa tgggcctcaa tggtacttca   9720

aaccttttga ttattcctaa ataaaaacat aaatatattt cac                     9763


<210>  10108
<211>  956
<212>  PRT
<213>  Homo sapiens

<400>  10108

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Val Lys 
865                 870                 875                 880


Gln Trp Phe Ala Glu Lys Met Gly Glu Glu Thr Arg Ala Val Ala Asp 
                885                 890                 895


Thr Gly Ser Glu Asp Gln Gly Pro Gly Thr Gly Glu Leu Thr Ala Val 
            900                 905                 910


His Lys Gly Met Gly Asp Thr Tyr Ser Glu Val Ser Glu Asn Ser Glu 
        915                 920                 925


Ser Trp Glu Pro Arg Val Pro Glu Ala Ser Ser Glu Pro Phe Asp Thr 
    930                 935                 940


Ser Ser Pro Gln Ala Gly Arg Gln Leu Glu Thr Asp 
945                 950                 955


<210>  10109
<211>  7234
<212>  DNA
<213>  Homo sapiens

<400>  10109
gtgaaaagac ctagatggta gaaggcaagc agtggaatgt gtctgggtat ccgagaaata     60

tacagaaagc acttaagaga acttaatcat ttttttctcc ctttccttag attgaatagg    120

gaaaacctgc tttctgcaaa caactgaaaa agctgcattt agaaactgtt tctttggccc    180

tcatcgagaa gctggaactt gtattgttag gccccttatg ggacaagctc tcaactgctg    240

atcacccagt gattgtcacc atggccagca agaggaaatc caccacacca tgcatgatcc    300

cagtgaagac tgtggtgttg caagatgcca gcatggaggc ccagcccgct gagaccttgc    360

ctgaaggacc ccagcaggat ctgcccccag aagcatctgc tgccagcagt gaggcagcac    420

agaaccccag cagtatcaga gccctttgac acatcgagtc cccaggctgg acgtcagctc    480

gaaacagact gaatttgatc tgattaatgt gaaggactgg ccagtctggg aaaccgcctg    540

ccacgtggaa gagccaaacc cgactctctg ctgccacatg ccgttcccat gcccggctgc    600

tgggcacctg ggagagcttc cagaatcctc gcagacagcc cagagcctgc cgctaccctc    660

ggcctgccca ccaccaagca agcagcaagc aagatggggt tctcatcagt tcttcctccc    720

acaatgtagg acctttcctt taccttccaa tggataaaat agttcagagt tcatagtcat    780

attcatagac acagaatcaa gcttttaaca tatacatcca cctctatatg ttaaataaaa    840

catcagatta tcaacactgt cattacgtag aaactttggt tagccaagca gtgcattgtc    900

agttacgtca tctctaaaaa tgacctgtgt ctgttctctg gggattgctg ggtcacaggt    960

gcccctcacc ttccacagtc aggcagggaa gttataggca caaagctacg tctggaaccc   1020

ctttgtgccc cctttgtgtt cctcaaggaa gcagtacctt tgaagagatc tctgctgcat   1080

taagtgatga ccggctacgt ttcatgtcag gcttgctttg ccttgtgggc tactcagtgc   1140

agaacctgct gtaaccctca gttcaaaaaa tggactggca atgtgattag cgttggatgc   1200

tttaccattc tctttagttg ttaccgtaat tctgcttttt catgggagtt tgaatcatgg   1260

accataactt ttcagttatc agatcaacta aagaaacatt tgttgttaag cctaatgtgc   1320

tgacctatgt gcctgcattt tttttttaat ctagacatgt ttggagtgag agaaagatgg   1380

aaaaaagaca tggggtaggg acgtaagtgg aaatctatag ccacagcctg aagctttgac   1440

cactgcggtt ttcagagccc tttctccaca ctcatttcag agcctcctat ggtttgggaa   1500

ggaataacac actggcccat tagtaagggt gaaggctgga gggatttgtt gacttcttgg   1560

aattatcaga ggtagggtgg tctttagcac aaagacttgc atgcagagat ccctggcaga   1620

acacccagag tgcccgtggc tcccacccca gggtctggcc ggtgtgctgg atgcatgccc   1680

aagggtgctg ggcatcactg gtccttgtga ggatgctttt aaagttttat atttatgtcc   1740

ccaaacttgg aaacaagaac tctactttag cctaaccctc atgtcctttt ttgaattgag   1800

aaaattacag gaaatggtgc ctttgaaaat tagaaaactt gcttacagag ctgttctaaa   1860

tggtaaatcc tcaatttccc caagaccggt tgctctgaga gtagctggta aagaggggcg   1920

aactaaagac ctgtccacct gtagctccgc tcatttctta gaaaccacct gcttcccaga   1980

gtgccaagcc acaagtacca ggcttcgtgg gcacagacac ctcctgggct gggcagagtg   2040

acagtgctag aagaccccag agagagggca agggctttgg gcaagaagca ctggtggtgt   2100

tttagggacc gtccttctcc cctacccagg gaactggacc tggcagggca ccgtgctcat   2160

gtggctccaa ggacaagcat ggcggtggcc ccttctgcct tccaggagag gtcttgcttt   2220

tgaaaccaaa atcatgttct tctaaagtgt catcttctgc cctccctgtc ccaataggga   2280

ccacatctta tttgtctcaa acagggactt gtgagtactt ggcaagtttt gcagcctatt   2340

tttgtattct taatttgggg agtaaagatg tttggtctca aaaacctttg aggaattgcc   2400

aagaatggcg agtgattgct ttccttcaga gaacagacac ttggaatttc tccttttagt   2460

gtttatatac gtgcagatta atttatatat atatatatac acacacacat atacagtata   2520

aatactcatt tgattctcgt aaaacgcgca tctggcgtgt gcagttgaga aacttggtgg   2580

cacatgggtg ttgggggagt agcctgtgtt ggagggacac cagtgcacta ggcagctggg   2640

gcggcccagg ctgaagccat ctccgggtgt ctgagaaacc acccagtgcc tcacctccag   2700

atcctgctgg catcacctcc agagccctgc atgcactggc tgaagagttg gtctgtggag   2760

aggattttct tggttacttg tattcacggt taatttacaa cccaaacagc aaaacacagt   2820

tggtggacaa gttcatgcag gacctacagt gacccagcca tgggcactag ctcatctttc   2880

aggtggaaaa gtacagtgct gcctgccctg gtatgttttt cttatagatg ttagccctgc   2940

ccaacagcca gggctacact acaaaaggca agaatgccca tgtaaggagc ccagcagtct   3000

ggacagatcc ttcttcctct gctgttggat gagagtgagt gagtatgctc tggaccttat   3060

ccttgaaaga tgatcaaaag cgatgatgag ggaggcagtc atcacgcagg tgcttaaagg   3120

gacattgtag gaggtactca agggtttggg ggcaaaaccc tgaatccagc cagtcgtgca   3180

cagagacaca cccacactag cccagtggca gtgggggatg tgggatggca gcagccaggt   3240

atgtagccct gtcacaggac agctcactgt ggttttgcac actgcctaag ggttaaattg   3300

tgttgttgcc ttcagtagaa ggcatttgtg ggctgcagag ttgagagttg ggtgaggtta   3360

gtctctcctg aagaaaaagc ctataaaaag tggctaatct tatccctttt ctctgtatgc   3420

agttggactc gtcagagata gtaaaatcat cttttagtgt ttttttgttg ctgatgtctt   3480

gtacccattt gttttttaca tggggttgta gatcgagttc tcaaaggtga aaccagatga   3540

tcattctgat aaaggaaatt taaatttgat acatatgctt tgtatatttt gattacttgt   3600

tttcgttttt gactataaag gagctttttt attttgggag gggaggagtg tcatttttga   3660

gaatcttggg ttcctgaaaa agaacgccct agttggatgg cttgccaggg ccttggggtt   3720

tggtagtgat tgtacaactt aaagctcctt tctcttggct gagtgacagg tggctgttca   3780

ggtggaccaa agcaccttga cacaaggact ccacactgtg ctctctagta gcacaaggag   3840

gaagttggac agaacattgg gtagtgcctt gcgggctcac acatgtacta gtggtctcat   3900

ctccagctag ccttgggagg ccgtcccacc aggaaatctc tctattccgt agcctgagat   3960

gtgcccttgt gggttttatc ctgctcagtc agtggcctag gggcaggtcc tgtgttctct   4020

ccctctctct cctggctctg ggacatctgt ccctggctgc ctttcatgga ggaaggacac   4080

tggcctttct ggttggatgc tgtgtggatg ctctctgctt gagcctcgtg gtctcttgtc   4140

tctttttgga ccaatatcct cagattggtg cagctttttc agttcagata tcacacccca   4200

agtggataaa ggcaacttgc aggagaggag agccagccaa gaagaaaatt ttaaaaccaa   4260

acctcgttta ggattttcct aaagtcatct tctctttttt cttgctcaga gtttacctgg   4320

gagatttcac cagtttgact caccatttgc agatgtgctt ttgtattaaa tttaaatttt   4380

cacatatcac atccattctc aaggtagtta tatgctggag aagaaaaatc ctctagacac   4440

atgaaggccc acatagtcaa gtcttccagg gcaaagccag cagcccaccc aggtcaggta   4500

gccagcaggg ctcagttccc ctcactccag acacggaccc tcctcttcag ggtctcttga   4560

cccagcttcc ttctctcctt ttacctgaga gcacagacct ctctcagcca gcctgcccag   4620

accacggggg gctactccca tgtagtttgg ggagcacttg atctcagaaa agctccattg   4680

tctgagcaaa tgggcagttg tggagctcaa gcctttctcc tgtgctcaag tcccttcccc   4740

aagcaaggct tcaacctcat ctacccacca tgtagttttc tctggccatt taagtggggc   4800

ggcagggaca tggttgggcc atgccacacc agggctggtg aggcaaccag ttttgatttt   4860

gacagagtgg ctggaggaaa agtggcaatc aaggtgctgc ttggtttgct ctgagtgcaa   4920

atggaaccaa caggtttctg ctgcaatctg tgtgttccca gtgccaggtc acaccaggag   4980

gggtggggca gggctaacca agtggtctct gaactcaccg agcgtctgca cttggttgtg   5040

aagttaatgg gagtacagag agcgtctggc cttggagagg ggttgagagc ctcctttttg   5100

gttcttcatt cctgagctct tgcctgccca caaatctgac ctctttgaat ggggacgcag   5160

tccttcaaca gagaagtttc tatggcaaag aagtttctat ttagctctag atccagcaga   5220

gtcatccatt ctaactgccc tgaagtctag agcaggggag ggaacccaga ggctggggat   5280

gagactaggc agaccctggt taccatatgg acaaggacag gggaaagcac ccccttcctc   5340

aatttctgaa agttctatct ttgggttcgc aggactttga ggatgataaa gaacatatag   5400

gtactagctt gttgttgctg gtccaaagct tccacagccc tgagaatttg gctttcgtgg   5460

ctgctctggc agctgagcga agggaggaag gcagccgctc tggtggggac tctaggcacc   5520

ttccctgctg tccacttgga taggcggtga gccccagggt actgagagga gcctgagcat   5580

ttacctgcca ttagtgcctc ttccttcagg agactggctt gaaacgtgtg ttcatgtgcg   5640

cgtgcacaca cacacatgag cacctgtatg tgttaatgaa tagtttttct tggttaatgc   5700

tttttaactt ctgttccttt ccgtaagtgg atgattcaaa attaacgtga cttggctggg   5760

cgcagtggct cacacctgta atcccagcac tttgggaggc caagggaggc ggatcacctg   5820

aggtcaggag ttcgagacca gcctgatcgg catggtgaaa ccccgtttct actaaaaata   5880

caaaaattag ccgggcgtgg tggtgcgcgc ctgtaatccc agctactcag gaggctgagg   5940

aaggagaatc acttgaaccc gggaggtgga ggttgcagtg agctgagatc gtgccactgc   6000

actccagcct gggcgacaga gcgaaactcc gtctcaaaaa aaaaaaaaaa acttaatgtg   6060

actggagtta aaagtgaaat gtcaggttgt ttagtcactg aatagagagc tacaagtgct   6120

tggtctttcc caagaatcaa acctgagtag aaatacattt aaaagaaaaa tctacatggt   6180

acctatgaat cctgtaattt gtttagggag atcttgtcac tcatccctgg ttcctgccca   6240

tactgtttgg tctcgttctt gcagtttgct tggaacaggg ccagagcccc acatgagatt   6300

gtcagcagga gtgaggagcg ccagtcccta ctcctcagca gggacccagc acagcaatcc   6360

ggttgttctc ggttagactg ggtcggggcc aggggagaag cagtcacccc tgtgtagagg   6420

gttcccgctg tgcttctgag cagttgcttt gttcagaagt gttaggaggg tcagattgtg   6480

ccataattgt tattaaagag aaaacacgcc caccttcctt tctcccctgc tggccattgt   6540

tcattgagtt ttactgaggg cagcctttgt ggaagtcagg gaggttgcca aaggcctgta   6600

gatgcctcct gacaaggtct tgattcctgg ttttctagca cccatttgca ttttggtctt   6660

cagcacaaag ccttgttccc tgtggccgga cttctgggca ataagactgg ggagtgactg   6720

ttgagcagtc tgctgtcagg agagatggct gaaaaggtga tcatcttggt gctaaacaag   6780

taagaggcaa ctgccctgtt tttgtttgtt ttgaggcaca atgaaacttt agccaaactc   6840

tgcaagaggg tcccatctcc tgccatggcc aggtgtgaga gaccaaaccg agaaaacagc   6900

atactctatc acttaagcct tgggtagaat gggaattctt taccctgggt aaacgtttta   6960

acaaaaaaat ggaacttaac ttcggtttgg actgtggtcg tgctgaggca ggagtggggt   7020

tgccctcttg gggctgaatc tccaggcctc acgaggtccc ctgtggggat gctgctattt   7080

ctaagatgca aattgcacat ttcctagatt ttgtatctgt ggatttggat aagggagggg   7140

aacacggaca aattgcttgt acaatttgaa atgggcctca atggtacttc aaaccttttg   7200

attattccta aataaaaaca taaatatatt tcac                               7234


<210>  10110
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  10110

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Ile Arg Ala Leu 
    50                  55                  60


<210>  10111
<211>  8941
<212>  DNA
<213>  Homo sapiens

<400>  10111
agcaaataga ctgaatgaaa gatgagcttc tgcctttata tccttctctc ctgctaccca     60

actcattgtg gtgaaggaaa aagaaaacgc gggtggagac tgcactatat gcttaggact    120

gaaatgcaac tgcagaagca acatgtgacc ttttagagat gcttgtggga ctgcataaag    180

tgaagaggga aactggaaaa aaacaatgaa attgaatagg gaaaacctgc tttctgcaaa    240

caactgaaaa agctgcattt agaaactgtt tctttggccc tcatcgagaa gctggaactt    300

gtattgttag gccccttatg ggacaagctc tcaactgctg atcacccagt gattgtcacc    360

atggccagca agaggaaatc caccacacca tgcatgatcc cagtgaagac tgtggtgttg    420

caagatgcca gcatggaggc ccagcccgct gagaccttgc ctgaaggacc ccagcaggat    480

ctgcccccag aagcatctgc tgccagcagt gaggcagcac agaaccccag cagtactgat    540

ggctctacac tggccaatgg gcatcggagc actttagatg gctatttata ttcctgtaaa    600

tactgcgatt tcagatccca tgacatgacc caatttgtgg gacatatgaa ctcagagcac    660

acagacttta ataaagaccc aacctttgta tgcagtgggt gcagttttct ggcaaaaacc    720

cctgaggggc tttccttgca caatgccaca tgtcactccg gggaagccag ctttgtgtgg    780

aacgtggcca agccagacaa tcatgtggtt gtggagcaga gcatccctga gagcaccagc    840

actcctgacc tagcgggtga gcccagtgct gaaggggctg atggacaggc agaaatcatc    900

attaccaaaa ctccaatcat gaagataatg aaaggcaaag ctgaagccaa aaaaattcat    960

acactcaagg agaatgtccc tagccagcct gtgggtgagg ccttaccaaa gctgtcgact   1020

ggagaaatgg aggtgagaga gggggaccat tccttcatca atggggcagt tccagtcagc   1080

caggcatctg ccagctctgc aaaaaacccc catgccgcca acgggcccct gataggaaca   1140

gtgccagttt tgccagctgg catagcacag ttcctctccc tccagcagca gcccccagtg   1200

catgcccaac accatgtcca ccagccactg cccacggcca aggcccttcc caaagtgatg   1260

atccccctga gcagcattcc aacgtacaat gcagccatgg actctaacag cttcctgaag   1320

aactccttcc acaagttccc ctaccccacc aaagccgagc tctgctattt gactgtggtg   1380

accaagtatc cagaagaaca gctcaagatc tggttcacag cccaaaggct gaagcagggg   1440

atcagctggt cccctgagga gattgaggat gcccggaaaa agatgttcaa tacagtcatc   1500

cagtctgtgc ctcagcccac aattacggtt ctaaataccc cactcgtcgc cagtgctggc   1560

aatgtccagc atctcatcca ggccgctctt ccaggtcacg ttgtggggca gccagagggt   1620

acaggagggg gacttctggt cactcagcca ttgatggcca atgggttgca agcaacaagt   1680

tcccctctcc ccctcacggt gacatccgtc cccaagcagc caggtgtggc acccattaac   1740

actgtgtgtt caaatacaac gtcagctgtg aaggtggtca atgcggccca gtcgctcctc   1800

acggcctgcc ccagcataac ctcccaagcc ttccttgatg ctagcatcta caaaaataag   1860

aaatctcatg aacagctgtc agctctgaaa gggagcttct gtcggaacca gttcccaggg   1920

cagagcgaag ttgaacatct cacaaaagtg acgggcctca gtaccagaga ggtgcggaaa   1980

tggttcagtg atcgtagata ccactgccgg aacttgaagg gctccagagc gatgatacct   2040

ggagatcaca gttccatcat cattgactct gtgccagagg tgtccttctc cccatcgtcc   2100

aaggtccctg aggtaacctg cattccgaca acagccacac tagcaaccca cccttctgcc   2160

aaacgacaat cttggcacca gactcctgac ttcacaccaa ccaaatacaa ggagagagcc   2220

cctgagcagc tcagagccct ggagagcagt tttgcacaaa accctcttcc tcttgatgag   2280

gaactggacc gcctgagaag tgaaaccaaa atgacccgac gagaaattga tagctggttt   2340

tcagagagac ggaaaaaagt gaatgctgag gagaccaaga aggctgagga gaatgcctct   2400

caggaggaag aggaggctgc tgaggatgag ggtggagaag aggatttggc cagtgagcta   2460

agggtctctg gtgaaaatgg ctctctggaa atgcccagca gccatatctt ggcagagcgc   2520

aaagtcagcc ccattaaaat caacctgaag aacctgaggg tcactgaagc caatggcagg   2580

aacgagattc cagggctggg tgcctgtgac cctgaggatg atgagtcaaa caaactggca   2640

gagcagctcc caggcaaagt gagctgcaaa aagactgccc agcagcggca cttgctgcgg   2700

cagctctttg tccagacaca gtggccaagc aaccaggact atgactccat catggcccag   2760

acgggtctgc cacggccaga ggtggtgcgc tggtttggag atagcaggta cgcactgaag   2820

aacggccaac tcaaatggta cgaagactat aagcgaggca acttcccacc agggctactg   2880

gtcattgccc ctggcaaccg ggagctcctg caggactatt acatgacaca caagatgctg   2940

tatgaagagg acctgcagaa cctctgtgac aagacccaga tgagctccca gcaggtcaag   3000

cagtggtttg ctgagaaaat gggggaggag accagagccg tggcagacac aggcagtgag   3060

gaccagggcc ctggtactgg tgagctcaca gcagttcaca aagggatggg tgacacctat   3120

tcagaggtgt ctgagaacag tgagtcgtgg gagccccgtg tccctgaggc cagctcagag   3180

ccctttgaca catcgagtcc ccaggctgga cgtcagctcg aaacagactg aatttgatct   3240

gattaatgtg aaggactggc cagtctggga aaccgcctgc cacgtggaag agccaaaccc   3300

gactctctgc tgccacatgc cgttcccatg cccggctgct gggcacctgg gagagcttcc   3360

agaatcctcg cagacagccc agagcctgcc gctaccctcg gcctgcccac caccaagcaa   3420

gcagcaagca agatggggtt ctcatcagtt cttcctccca caatgtagga cctttccttt   3480

accttccaat ggataaaata gttcagagtt catagtcata ttcatagaca cagaatcaag   3540

cttttaacat atacatccac ctctatatgt taaataaaac atcagattat caacactgtc   3600

attacgtaga aactttggtt agccaagcag tgcattgtca gttacgtcat ctctaaaaat   3660

gacctgtgtc tgttctctgg ggattgctgg gtcacaggtg cccctcacct tccacagtca   3720

ggcagggaag ttataggcac aaagctacgt ctggaacccc tttgtgcccc ctttgtgttc   3780

ctcaaggaag cagtaccttt gaagagatct ctgctgcatt aagtgatgac cggctacgtt   3840

tcatgtcagg cttgctttgc cttgtgggct actcagtgca gaacctgctg taaccctcag   3900

ttcaaaaaat ggactggcaa tgtgattagc gttggatgct ttaccattct ctttagttgt   3960

taccgtaatt ctgctttttc atgggagttt gaatcatgga ccataacttt tcagttatca   4020

gatcaactaa agaaacattt gttgttaagc ctaatgtgct gacctatgtg cctgcatttt   4080

ttttttaatc tagacatgtt tggagtgaga gaaagatgga aaaaagacat ggggtaggga   4140

cgtaagtgga aatctatagc cacagcctga agctttgacc actgcggttt tcagagccct   4200

ttctccacac tcatttcaga gcctcctatg gtttgggaag gaataacaca ctggcccatt   4260

agtaagggtg aaggctggag ggatttgttg acttcttgga attatcagag gtagggtggt   4320

ctttagcaca aagacttgca tgcagagatc cctggcagaa cacccagagt gcccgtggct   4380

cccaccccag ggtctggccg gtgtgctgga tgcatgccca agggtgctgg gcatcactgg   4440

tccttgtgag gatgctttta aagttttata tttatgtccc caaacttgga aacaagaact   4500

ctactttagc ctaaccctca tgtccttttt tgaattgaga aaattacagg aaatggtgcc   4560

tttgaaaatt agaaaacttg cttacagagc tgttctaaat ggtaaatcct caatttcccc   4620

aagaccggtt gctctgagag tagctggtaa agaggggcga actaaagacc tgtccacctg   4680

tagctccgct catttcttag aaaccacctg cttcccagag tgccaagcca caagtaccag   4740

gcttcgtggg cacagacacc tcctgggctg ggcagagtga cagtgctaga agaccccaga   4800

gagagggcaa gggctttggg caagaagcac tggtggtgtt ttagggaccg tccttctccc   4860

ctacccaggg aactggacct ggcagggcac cgtgctcatg tggctccaag gacaagcatg   4920

gcggtggccc cttctgcctt ccaggagagg tcttgctttt gaaaccaaaa tcatgttctt   4980

ctaaagtgtc atcttctgcc ctccctgtcc caatagggac cacatcttat ttgtctcaaa   5040

cagggacttg tgagtacttg gcaagttttg cagcctattt ttgtattctt aatttgggga   5100

gtaaagatgt ttggtctcaa aaacctttga ggaattgcca agaatggcga gtgattgctt   5160

tccttcagag aacagacact tggaatttct ccttttagtg tttttgattc tcgtaaaacg   5220

cgcatctggc gtgtgcagtt gagaaacttg gtggcacatg ggtgttgggg gagtagcctg   5280

tgttggaggg acaccagtgc actaggcagc tggggcggcc caggctgaag ccatctccgg   5340

gtgtctgaga aaccacccag tgcctcacct ccagatcctg ctggcatcac ctccagagcc   5400

ctgcatgcac tggctgaaga gttggtctgt ggagaggatt ttcttggtta cttgtattca   5460

cggttaattt acaacccaaa cagcaaaaca cagttggtgg acaagttcat gcaggaccta   5520

cagtgaccca gccatgggca ctagctcatc tttcaggtgg aaaagtacag tgctgcctgc   5580

cctggtatgt ttttcttata gatgttagcc ctgcccaaca gccagggcta cactacaaaa   5640

ggcaagaatg cccatgtaag gagcccagca gtctggacag atccttcttc ctctgctgtt   5700

ggatgagagt gagtgagtat gctctggacc ttatccttga aagatgatca aaagcgatga   5760

tgagggaggc agtcatcacg caggtgctta aagggacatt gtaggaggta ctcaagggtt   5820

tgggggcaaa accctgaatc cagccagtcg tgcacagaga cacacccaca ctagcccagt   5880

ggcagtgggg gatgtgggat ggcagcagcc aggtatgtag ccctgtcaca ggacagctca   5940

ctgtggtttt gcacactgcc taagggttaa attgtgttgt tgccttcagt agaaggcatt   6000

tgtgggctgc agagttgaga gttgggtgag gttagtctct cctgaagaaa aagcctataa   6060

aaagtggcta atcttatccc ttttctctgt atgcagttgg actcgtcaga gatagtaaaa   6120

tcatctttta gtgttttttt gttgctgatg tcttgtaccc atttgttttt tacatggggt   6180

tgtagatcga gttctcaaag gtgaaaccag atgatcattc tgataaagga aatttaaatt   6240

tgatacatat gctttgtata ttttgattac ttgttttcgt ttttgactat aaaggagtct   6300

tttttcttgc tcagagttta cctgggagat ttcaccagtt tgactcacca tttgcagatg   6360

tgcttttgta ttaaatttaa attttcacat atcacatcca ttctcaaggt agttatatgc   6420

tggagaagaa aaatcctcta gacacatgaa ggcccacata gtcaagtctt ccagggcaaa   6480

gccagcagcc cacccaggtc aggtagccag cagggctcag ttcccctcac tccagacacg   6540

gaccctcctc ttcagggtct cttgacccag cttccttctc tccttttacc tgagagcaca   6600

gacctctctc agccagcctg cccagaccac ggggggctac tcccatgtag tttggggagc   6660

acttgatctc agaaaagctc cattgtctga gcaaatgggc agttgtggag ctcaagcctt   6720

tctcctgtgc tcaagtccct tccccaagca aggcttcaac ctcatctacc caccatgtag   6780

ttttctctgg ccatttaagt ggggcggcag ggacatggtt gggccatgcc acaccagggc   6840

tggtgaggca accagttttg attttgacag agtggctgga ggaaaagtgg caatcaaggt   6900

gctgcttggt ttgctctgag tgcaaatgga accaacaggt ttctgctgca atctgtgtgt   6960

tcccagtgcc aggtcacacc aggaggggtg gggcagggct aaccaagtgg tctctgaact   7020

caccgagcgt ctgcacttgg ttgtgaagtt aatgggagta cagagagcgt ctggccttgg   7080

agaggggttg agagcctcct ttttggttct tcattcctga gctcttgcct gcccacaaat   7140

ctgacctctt tgaatgggga cgcagtcctt caacagagaa gtttctatgg caaagaagtt   7200

tctatttagc tctagatcca gcagagtcat ccattctaac tgccctgaag tctagagcag   7260

gggagggaac ccagaggctg gggatgagac taggcagacc ctggttacca tatggacaag   7320

gacaggggaa agcaccccct tcctcaattt ctgaaagttc tatctttggg ttcgcaggac   7380

tttgaggatg ataaagaaca tataggtact agcttgttgt tgctggtcca aagcttccac   7440

agccctgaga atttggcttt cgtggctgct ctggcagctg agcgaaggga ggaaggcagc   7500

cgctctggtg gggactctag gcaccttccc tgctgtccac ttggataggc ggtgagcccc   7560

agggtactga gaggagcctg agcatttacc tgccattagt gcctcttcct tcaggagact   7620

ggcttgaaac gtgtgttcat gtgcgcgtgc acacacacac atgagcacct gtatgtgtta   7680

atgaatagtt tttcttggtt aatgcttttt aacttctgtt cctttccgta agtggatgat   7740

tcaaaattaa cgtgacttct taatgtgact ggagttaaaa gtgaaatgtc aggttgttta   7800

gtcactgaat agagagctac aagtgcttgg tctttcccaa gaatcaaacc tgagtagaaa   7860

tacatttaaa agaaaaatct acatggtacc tatgaatcct gtaatttgtt tagggagatc   7920

ttgtcactca tccctggttc ctgcccatac tgtttggtct cgttcttgca gtttgcttgg   7980

aacagggcca gagccccaca tgagattgtc agcaggagtg aggagcgcca gtccctactc   8040

ctcagcaggg acccagcaca gcaatccggt tgttctcggt tagactgggt cggggccagg   8100

ggagaagcag tcacccctgt gtagagggtt cccgctgtgc ttctgagcag ttgctttgtt   8160

cagaagtgtt aggagggtca gattgtgcca taattgttat taaagagaaa acacgcccac   8220

cttcctttct cccctgctgg ccattgttca ttgagtttta ctgagggcag cctttgtgga   8280

agtcagggag gttgccaaag gcctgtagat gcctcctgac aaggtcttga ttcctggttt   8340

tctagcaccc atttgcattt tggtcttcag cacaaagcct tgttccctgt ggccggactt   8400

ctgggcaata agactgggga gtgactgttg agcagtctgc tgtcaggaga gatggctgaa   8460

aaggtgatca tcttggtgct aaacaagtaa gaggcaactg ccctgttttt gtttgttttg   8520

aggcacaatg aaactttagc caaactctgc aagagggtcc catctcctgc catggccagg   8580

tgtgagagac caaaccgaga aaacagcata ctctatcact taagccttgg gtagaatggg   8640

aattctttac cctgggtaaa cgttttaaca aaaaaatgga acttaacttc ggtttggact   8700

gtggtcgtgc tgaggcagga gtggggttgc cctcttgggg ctgaatctcc aggcctcacg   8760

aggtcccctg tggggatgct gctatttcta agatgcaaat tgcacatttc ctagattttg   8820

tatctgtgga tttggataag ggaggggaac acggacaaat tgcttgtaca atttgaaatg   8880

ggcctcaatg gtacttcaaa ccttttgatt attcctaaat aaaaacataa atatatttca   8940

c                                                                   8941


<210>  10112
<211>  956
<212>  PRT
<213>  Homo sapiens

<400>  10112

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Val Lys 
865                 870                 875                 880


Gln Trp Phe Ala Glu Lys Met Gly Glu Glu Thr Arg Ala Val Ala Asp 
                885                 890                 895


Thr Gly Ser Glu Asp Gln Gly Pro Gly Thr Gly Glu Leu Thr Ala Val 
            900                 905                 910


His Lys Gly Met Gly Asp Thr Tyr Ser Glu Val Ser Glu Asn Ser Glu 
        915                 920                 925


Ser Trp Glu Pro Arg Val Pro Glu Ala Ser Ser Glu Pro Phe Asp Thr 
    930                 935                 940


Ser Ser Pro Gln Ala Gly Arg Gln Leu Glu Thr Asp 
945                 950                 955


<210>  10113
<211>  9991
<212>  DNA
<213>  Homo sapiens

<400>  10113
gtgatagccg tcaaaggcag caaatagact gaatgaaaga tgagcttctg cctttatatc     60

cttctctcct gctacccaac tcattgtggt gaaggaaaaa gaaaacgcgg gtggagactg    120

cactatatgc ttaggactga aatgcaactg cagaagcaac atgtgacctt ttagagatgc    180

ttgtgggact gcataaagtg aagagggaaa ctggaaaaaa acaatgaaat tgaataggga    240

aaacctgctt tctgcaaaca actgaaaaag ctgcatttag aaactgtttc tttggccctc    300

atcgagaagc tggaacttgt attgttaggc cccttatggg acaagctctc aactgctgat    360

cacccagtga ttgtcaccat ggccagcaag aggaaatcca ccacaccatg catgatccca    420

gtgaagactg tggtgttgca agatgccagc atggaggccc agcccgctga gaccttgcct    480

gaaggacccc agcaggatct gcccccagaa gcatctgctg ccagcagtga ggcagcacag    540

aaccccagca gtactgatgg ctctacactg gccaatgggc atcggagcac tttagatggc    600

tatttatatt cctgtaaata ctgcgatttc agatcccatg acatgaccca atttgtggga    660

catatgaact cagagcacac agactttaat aaagacccaa cctttgtatg cagtgggtgc    720

agttttctgg caaaaacccc tgaggggctt tccttgcaca atgccacatg tcactccggg    780

gaagccagct ttgtgtggaa cgtggccaag ccagacaatc atgtggttgt ggagcagagc    840

atccctgaga gcaccagcac tcctgaccta gcgggtgagc ccagtgctga aggggctgat    900

ggacaggcag aaatcatcat taccaaaact ccaatcatga agataatgaa aggcaaagct    960

gaagccaaaa aaattcatac actcaaggag aatgtcccta gccagcctgt gggtgaggcc   1020

ttaccaaagc tgtcgactgg agaaatggag gtgagagagg gggaccattc cttcatcaat   1080

ggggcagttc cagtcagcca ggcatctgcc agctctgcaa aaaaccccca tgccgccaac   1140

gggcccctga taggaacagt gccagttttg ccagctggca tagcacagtt cctctccctc   1200

cagcagcagc ccccagtgca tgcccaacac catgtccacc agccactgcc cacggccaag   1260

gcccttccca aagtgatgat ccccctgagc agcattccaa cgtacaatgc agccatggac   1320

tctaacagct tcctgaagaa ctccttccac aagttcccct accccaccaa agccgagctc   1380

tgctatttga ctgtggtgac caagtatcca gaagaacagc tcaagatctg gttcacagcc   1440

caaaggctga agcaggggat cagctggtcc cctgaggaga ttgaggatgc ccggaaaaag   1500

atgttcaata cagtcatcca gtctgtgcct cagcccacaa ttacggttct aaatacccca   1560

ctcgtcgcca gtgctggcaa tgtccagcat ctcatccagg ccgctcttcc aggtcacgtt   1620

gtggggcagc cagagggtac aggaggggga cttctggtca ctcagccatt gatggccaat   1680

gggttgcaag caacaagttc ccctctcccc ctcacggtga catccgtccc caagcagcca   1740

ggtgtggcac ccattaacac tgtgtgttca aatacaacgt cagctgtgaa ggtggtcaat   1800

gcggcccagt cgctcctcac ggcctgcccc agcataacct cccaagcctt ccttgatgct   1860

agcatctaca aaaataagaa atctcatgaa cagctgtcag ctctgaaagg gagcttctgt   1920

cggaaccagt tcccagggca gagcgaagtt gaacatctca caaaagtgac gggcctcagt   1980

accagagagg tgcggaaatg gttcagtgat cgtagatacc actgccggaa cttgaagggc   2040

tccagagcga tgatacctgg agatcacagt tccatcatca ttgactctgt gccagaggtg   2100

tccttctccc catcgtccaa ggtccctgag gtaacctgca ttccgacaac agccacacta   2160

gcaacccacc cttctgccaa acgacaatct tggcaccaga ctcctgactt cacaccaacc   2220

aaatacaagg agagagcccc tgagcagctc agagccctgg agagcagttt tgcacaaaac   2280

cctcttcctc ttgatgagga actggaccgc ctgagaagtg aaaccaaaat gacccgacga   2340

gaaattgata gctggttttc agagagacgg aaaaaagtga atgctgagga gaccaagaag   2400

gctgaggaga atgcctctca ggaggaagag gaggctgctg aggatgaggg tggagaagag   2460

gatttggcca gtgagctaag ggtctctggt gaaaatggct ctctggaaat gcccagcagc   2520

catatcttgg cagagcgcaa agtcagcccc attaaaatca acctgaagaa cctgagggtc   2580

actgaagcca atggcaggaa cgagattcca gggctgggtg cctgtgaccc tgaggatgat   2640

gagtcaaaca aactggcaga gcagctccca ggcaaagtga gctgcaaaaa gactgcccag   2700

cagcggcact tgctgcggca gctctttgtc cagacacagt ggccaagcaa ccaggactat   2760

gactccatca tggcccagac gggtctgcca cggccagagg tggtgcgctg gtttggagat   2820

agcaggtacg cactgaagaa cggccaactc aaatggtacg aagactataa gcgaggcaac   2880

ttcccaccag ggctactggt cattgcccct ggcaaccggg agctcctgca ggactattac   2940

atgacacaca agatgctgta tgaagaggac ctgcagaacc tctgtgacaa gacccagatg   3000

agctcccagc aggtcaagca gtggtttgct gagaaaatgg gggaggagac cagagccgtg   3060

gcagacacag gcagtgagga ccagggccct ggtactggtg agctcacagc agttcacaaa   3120

gggatgggtg acacctattc agaggtgtct gagaacagtg agtcgtggga gccccgtgtc   3180

cctgaggcca gctcagagcc ctttgacaca tcgagtcccc aggctggacg tcagctcgaa   3240

acagactgaa tttgatctga ttaatgtgaa ggactggcca gtctgggaaa ccgcctgcca   3300

cgtggaagag ccaaacccga ctctctgctg ccacatgccg ttcccatgcc cggctgctgg   3360

gcacctggga gagcttccag aatcctcgca gacagcccag agcctgccgc taccctcggc   3420

ctgcccacca ccaagcaagc agcaagcaag atggggttct catcagttct tcctcccaca   3480

atgtaggacc tttcctttac cttccaatgg ataaaatagt tcagagttca tagtcatatt   3540

catagacaca gaatcaagct tttaacatat acatccacct ctatatgtta aataaaacat   3600

cagattatca acactgtcat tacgtagaaa ctttggttag ccaagcagtg cattgtcagt   3660

tacgtcatct ctaaaaatga cctgtgtctg ttctctgggg attgctgggt cacaggtgcc   3720

cctcaccttc cacagtcagg cagggaagtt ataggcacaa agctacgtct ggaacccctt   3780

tgtgccccct ttgtgttcct caaggaagca gtacctttga agagatctct gctgcattaa   3840

gtgatgaccg gctacgtttc atgtcaggct tgctttgcct tgtgggctac tcagtgcaga   3900

acctgctgta accctcagtt caaaaaatgg actggcaatg tgattagcgt tggatgcttt   3960

accattctct ttagttgtta ccgtaattct gctttttcat gggagtttga atcatggacc   4020

ataacttttc agttatcaga tcaactaaag aaacatttgt tgttaagcct aatgtgctga   4080

cctatgtgcc tgcatttttt ttttaatcta gacatgtttg gagtgagaga aagatggaaa   4140

aaagacatgg ggtagggacg taagtggaaa tctatagcca cagcctgaag ctttgaccac   4200

tgcggttttc agagcccttt ctccacactc atttcagagc ctcctatggt ttgggaagga   4260

ataacacact ggcccattag taagggtgaa ggctggaggg atttgttgac ttcttggaat   4320

tatcagaggt agggtggtct ttagcacaaa gacttgcatg cagagatccc tggcagaaca   4380

cccagagtgc ccgtggctcc caccccaggg tctggccggt gtgctggatg catgcccaag   4440

ggtgctgggc atcactggtc cttgtgagga tgcttttaaa gttttatatt tatgtcccca   4500

aacttggaaa caagaactct actttagcct aaccctcatg tccttttttg aattgagaaa   4560

attacaggaa atggtgcctt tgaaaattag aaaacttgct tacagagctg ttctaaatgg   4620

taaatcctca atttccccaa gaccggttgc tctgagagta gctggtaaag aggggcgaac   4680

taaagacctg tccacctgta gctccgctca tttcttagaa accacctgct tcccagagtg   4740

ccaagccaca agtaccaggc ttcgtgggca cagacacctc ctgggctggg cagagtgaca   4800

gtgctagaag accccagaga gagggcaagg gctttgggca agaagcactg gtggtgtttt   4860

agggaccgtc cttctcccct acccagggaa ctggacctgg cagggcaccg tgctcatgtg   4920

gctccaagga caagcatggc ggtggcccct tctgccttcc aggagaggtc ttgcttttga   4980

aaccaaaatc atgttcttct aaagtgtcat cttctgccct ccctgtccca atagggacca   5040

catcttattt gtctcaaaca gggacttgtg agtacttggc aagttttgca gcctattttt   5100

gtattcttaa tttggggagt aaagatgttt ggtctcaaaa acctttgagg aattgccaag   5160

aatggcgagt gattgctttc cttcagagaa cagacacttg gaatttctcc ttttagtgtt   5220

tatatacgtg cagattaatt tatatatata tatatacaca cacacatata cagtataaat   5280

actcatttga ttctcgtaaa acgcgcatct ggcgtgtgca gttgagaaac ttggtggcac   5340

atgggtgttg ggggagtagc ctgtgttgga gggacaccag tgcactaggc agctggggcg   5400

gcccaggctg aagccatctc cgggtgtctg agaaaccacc cagtgcctca cctccagatc   5460

ctgctggcat cacctccaga gccctgcatg cactggctga agagttggtc tgtggagagg   5520

attttcttgg ttacttgtat tcacggttaa tttacaaccc aaacagcaaa acacagttgg   5580

tggacaagtt catgcaggac ctacagtgac ccagccatgg gcactagctc atctttcagg   5640

tggaaaagta cagtgctgcc tgccctggta tgtttttctt atagatgtta gccctgccca   5700

acagccaggg ctacactaca aaaggcaaga atgcccatgt aaggagccca gcagtctgga   5760

cagatccttc ttcctctgct gttggatgag agtgagtgag tatgctctgg accttatcct   5820

tgaaagatga tcaaaagcga tgatgaggga ggcagtcatc acgcaggtgc ttaaagggac   5880

attgtaggag gtactcaagg gtttgggggc aaaaccctga atccagccag tcgtgcacag   5940

agacacaccc acactagccc agtggcagtg ggggatgtgg gatggcagca gccaggtatg   6000

tagccctgtc acaggacagc tcactgtggt tttgcacact gcctaagggt taaattgtgt   6060

tgttgccttc agtagaaggc atttgtgggc tgcagagttg agagttgggt gaggttagtc   6120

tctcctgaag aaaaagccta taaaaagtgg ctaatcttat cccttttctc tgtatgcagt   6180

tggactcgtc agagatagta aaatcatctt ttagtgtttt tttgttgctg atgtcttgta   6240

cccatttgtt ttttacatgg ggttgtagat cgagttctca aaggtgaaac cagatgatca   6300

ttctgataaa ggaaatttaa atttgataca tatgctttgt atattttgat tacttgtttt   6360

cgtttttgac tataaaggag cttttttatt ttgggagggg aggagtgtca tttttgagaa   6420

tcttgggttc ctgaaaaaga acgccctagt tggatggctt gccagggcct tggggtttgg   6480

tagtgattgt acaacttaaa gctcctttct cttggctgag tgacaggtgg ctgttcaggt   6540

ggaccaaagc accttgacac aaggactcca cactgtgctc tctagtagca caaggaggaa   6600

gttggacaga acattgggta gtgccttgcg ggctcacaca tgtactagtg gtctcatctc   6660

cagctagcct tgggaggccg tcccaccagg aaatctctct attccgtagc ctgagatgtg   6720

cccttgtggg ttttatcctg ctcagtcagt ggcctagggg caggtcctgt gttctctccc   6780

tctctctcct ggctctggga catctgtccc tggctgcctt tcatggagga aggacactgg   6840

cctttctggt tggatgctgt gtggatgctc tctgcttgag cctcgtggtc tcttgtctct   6900

ttttggacca atatcctcag attggtgcag ctttttcagt tcagatatca caccccaagt   6960

ggataaaggc aacttgcagg agaggagagc cagccaagaa gaaaatttta aaaccaaacc   7020

tcgtttagga ttttcctaaa gtcatcttct cttttttctt gctcagagtt tacctgggag   7080

atttcaccag tttgactcac catttgcaga tgtgcttttg tattaaattt aaattttcac   7140

atatcacatc cattctcaag gtagttatat gctggagaag aaaaatcctc tagacacatg   7200

aaggcccaca tagtcaagtc ttccagggca aagccagcag cccacccagg tcaggtagcc   7260

agcagggctc agttcccctc actccagaca cggaccctcc tcttcagggt ctcttgaccc   7320

agcttccttc tctcctttta cctgagagca cagacctctc tcagccagcc tgcccagacc   7380

acggggggct actcccatgt agtttgggga gcacttgatc tcagaaaagc tccattgtct   7440

gagcaaatgg gcagttgtgg agctcaagcc tttctcctgt gctcaagtcc cttccccaag   7500

caaggcttca acctcatcta cccaccatgt agttttctct ggccatttaa gtggggcggc   7560

agggacatgg ttgggccatg ccacaccagg gctggtgagg caaccagttt tgattttgac   7620

agagtggctg gaggaaaagt ggcaatcaag gtgctgcttg gtttgctctg agtgcaaatg   7680

gaaccaacag gtttctgctg caatctgtgt gttcccagtg ccaggtcaca ccaggagggg   7740

tggggcaggg ctaaccaagt ggtctctgaa ctcaccgagc gtctgcactt ggttgtgaag   7800

ttaatgggag tacagagagc gtctggcctt ggagaggggt tgagagcctc ctttttggtt   7860

cttcattcct gagctcttgc ctgcccacaa atctgacctc tttgaatggg gacgcagtcc   7920

ttcaacagag aagtttctat ggcaaagaag tttctattta gctctagatc cagcagagtc   7980

atccattcta actgccctga agtctagagc aggggaggga acccagaggc tggggatgag   8040

actaggcaga ccctggttac catatggaca aggacagggg aaagcacccc cttcctcaat   8100

ttctgaaagt tctatctttg ggttcgcagg actttgagga tgataaagaa catataggta   8160

ctagcttgtt gttgctggtc caaagcttcc acagccctga gaatttggct ttcgtggctg   8220

ctctggcagc tgagcgaagg gaggaaggca gccgctctgg tggggactct aggcaccttc   8280

cctgctgtcc acttggatag gcggtgagcc ccagggtact gagaggagcc tgagcattta   8340

cctgccatta gtgcctcttc cttcaggaga ctggcttgaa acgtgtgttc atgtgcgcgt   8400

gcacacacac acatgagcac ctgtatgtgt taatgaatag tttttcttgg ttaatgcttt   8460

ttaacttctg ttcctttccg taagtggatg attcaaaatt aacgtgactt ggctgggcgc   8520

agtggctcac acctgtaatc ccagcacttt gggaggccaa gggaggcgga tcacctgagg   8580

tcaggagttc gagaccagcc tgatcggcat ggtgaaaccc cgtttctact aaaaatacaa   8640

aaattagccg ggcgtggtgg tgcgcgcctg taatcccagc tactcaggag gctgaggaag   8700

gagaatcact tgaacccggg aggtggaggt tgcagtgagc tgagatcgtg ccactgcact   8760

ccagcctggg cgacagagcg aaactccgtc tcaaaaaaaa aaaaaaaact taatgtgact   8820

ggagttaaaa gtgaaatgtc aggttgttta gtcactgaat agagagctac aagtgcttgg   8880

tctttcccaa gaatcaaacc tgagtagaaa tacatttaaa agaaaaatct acatggtacc   8940

tatgaatcct gtaatttgtt tagggagatc ttgtcactca tccctggttc ctgcccatac   9000

tgtttggtct cgttcttgca gtttgcttgg aacagggcca gagccccaca tgagattgtc   9060

agcaggagtg aggagcgcca gtccctactc ctcagcaggg acccagcaca gcaatccggt   9120

tgttctcggt tagactgggt cggggccagg ggagaagcag tcacccctgt gtagagggtt   9180

cccgctgtgc ttctgagcag ttgctttgtt cagaagtgtt aggagggtca gattgtgcca   9240

taattgttat taaagagaaa acacgcccac cttcctttct cccctgctgg ccattgttca   9300

ttgagtttta ctgagggcag cctttgtgga agtcagggag gttgccaaag gcctgtagat   9360

gcctcctgac aaggtcttga ttcctggttt tctagcaccc atttgcattt tggtcttcag   9420

cacaaagcct tgttccctgt ggccggactt ctgggcaata agactgggga gtgactgttg   9480

agcagtctgc tgtcaggaga gatggctgaa aaggtgatca tcttggtgct aaacaagtaa   9540

gaggcaactg ccctgttttt gtttgttttg aggcacaatg aaactttagc caaactctgc   9600

aagagggtcc catctcctgc catggccagg tgtgagagac caaaccgaga aaacagcata   9660

ctctatcact taagccttgg gtagaatggg aattctttac cctgggtaaa cgttttaaca   9720

aaaaaatgga acttaacttc ggtttggact gtggtcgtgc tgaggcagga gtggggttgc   9780

cctcttgggg ctgaatctcc aggcctcacg aggtcccctg tggggatgct gctatttcta   9840

agatgcaaat tgcacatttc ctagattttg tatctgtgga tttggataag ggaggggaac   9900

acggacaaat tgcttgtaca atttgaaatg ggcctcaatg gtacttcaaa ccttttgatt   9960

attcctaaat aaaaacataa atatatttca c                                  9991


<210>  10114
<211>  956
<212>  PRT
<213>  Homo sapiens

<400>  10114

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Val Lys 
865                 870                 875                 880


Gln Trp Phe Ala Glu Lys Met Gly Glu Glu Thr Arg Ala Val Ala Asp 
                885                 890                 895


Thr Gly Ser Glu Asp Gln Gly Pro Gly Thr Gly Glu Leu Thr Ala Val 
            900                 905                 910


His Lys Gly Met Gly Asp Thr Tyr Ser Glu Val Ser Glu Asn Ser Glu 
        915                 920                 925


Ser Trp Glu Pro Arg Val Pro Glu Ala Ser Ser Glu Pro Phe Asp Thr 
    930                 935                 940


Ser Ser Pro Gln Ala Gly Arg Gln Leu Glu Thr Asp 
945                 950                 955


<210>  10115
<211>  9951
<212>  DNA
<213>  Homo sapiens

<400>  10115
cctgcgccgg ccgcccgccc ggccgcgggg agggaggccc gcagcgcggg aagagcggcc     60

cggtcgcggg cgccgccacc gccgccgctg ccaggactga aatgcaactg cagaagcaac    120

atgtgacctt ttagagatgc ttgtgggact gcataaagtg aagagggaaa ctggaaaaaa    180

acaatgaaat tgaataggga aaacctgctt tctgcaaaca actgaaaaag ctgcatttag    240

aaactgtttc tttggccctc atcgagaagc tggaacttgt attgttaggc cccttatggg    300

acaagctctc aactgctgat cacccagtga ttgtcaccat ggccagcaag aggaaatcca    360

ccacaccatg catgatccca gtgaagactg tggtgttgca agatgccagc atggaggccc    420

agcccgctga gaccttgcct gaaggacccc agcaggatct gcccccagaa gcatctgctg    480

ccagcagtga ggcagcacag aaccccagca gtactgatgg ctctacactg gccaatgggc    540

atcggagcac tttagatggc tatttatatt cctgtaaata ctgcgatttc agatcccatg    600

acatgaccca atttgtggga catatgaact cagagcacac agactttaat aaagacccaa    660

cctttgtatg cagtgggtgc agttttctgg caaaaacccc tgaggggctt tccttgcaca    720

atgccacatg tcactccggg gaagccagct ttgtgtggaa cgtggccaag ccagacaatc    780

atgtggttgt ggagcagagc atccctgaga gcaccagcac tcctgaccta gcgggtgagc    840

ccagtgctga aggggctgat ggacaggcag aaatcatcat taccaaaact ccaatcatga    900

agataatgaa aggcaaagct gaagccaaaa aaattcatac actcaaggag aatgtcccta    960

gccagcctgt gggtgaggcc ttaccaaagc tgtcgactgg agaaatggag gtgagagagg   1020

gggaccattc cttcatcaat ggggcagttc cagtcagcca ggcatctgcc agctctgcaa   1080

aaaaccccca tgccgccaac gggcccctga taggaacagt gccagttttg ccagctggca   1140

tagcacagtt cctctccctc cagcagcagc ccccagtgca tgcccaacac catgtccacc   1200

agccactgcc cacggccaag gcccttccca aagtgatgat ccccctgagc agcattccaa   1260

cgtacaatgc agccatggac tctaacagct tcctgaagaa ctccttccac aagttcccct   1320

accccaccaa agccgagctc tgctatttga ctgtggtgac caagtatcca gaagaacagc   1380

tcaagatctg gttcacagcc caaaggctga agcaggggat cagctggtcc cctgaggaga   1440

ttgaggatgc ccggaaaaag atgttcaata cagtcatcca gtctgtgcct cagcccacaa   1500

ttacggttct aaatacccca ctcgtcgcca gtgctggcaa tgtccagcat ctcatccagg   1560

ccgctcttcc aggtcacgtt gtggggcagc cagagggtac aggaggggga cttctggtca   1620

ctcagccatt gatggccaat gggttgcaag caacaagttc ccctctcccc ctcacggtga   1680

catccgtccc caagcagcca ggtgtggcac ccattaacac tgtgtgttca aatacaacgt   1740

cagctgtgaa ggtggtcaat gcggcccagt cgctcctcac ggcctgcccc agcataacct   1800

cccaagcctt ccttgatgct agcatctaca aaaataagaa atctcatgaa cagctgtcag   1860

ctctgaaagg gagcttctgt cggaaccagt tcccagggca gagcgaagtt gaacatctca   1920

caaaagtgac gggcctcagt accagagagg tgcggaaatg gttcagtgat cgtagatacc   1980

actgccggaa cttgaagggc tccagagcga tgatacctgg agatcacagt tccatcatca   2040

ttgactctgt gccagaggtg tccttctccc catcgtccaa ggtccctgag gtaacctgca   2100

ttccgacaac agccacacta gcaacccacc cttctgccaa acgacaatct tggcaccaga   2160

ctcctgactt cacaccaacc aaatacaagg agagagcccc tgagcagctc agagccctgg   2220

agagcagttt tgcacaaaac cctcttcctc ttgatgagga actggaccgc ctgagaagtg   2280

aaaccaaaat gacccgacga gaaattgata gctggttttc agagagacgg aaaaaagtga   2340

atgctgagga gaccaagaag gctgaggaga atgcctctca ggaggaagag gaggctgctg   2400

aggatgaggg tggagaagag gatttggcca gtgagctaag ggtctctggt gaaaatggct   2460

ctctggaaat gcccagcagc catatcttgg cagagcgcaa agtcagcccc attaaaatca   2520

acctgaagaa cctgagggtc actgaagcca atggcaggaa cgagattcca gggctgggtg   2580

cctgtgaccc tgaggatgat gagtcaaaca aactggcaga gcagctccca ggcaaagtga   2640

gctgcaaaaa gactgcccag cagcggcact tgctgcggca gctctttgtc cagacacagt   2700

ggccaagcaa ccaggactat gactccatca tggcccagac gggtctgcca cggccagagg   2760

tggtgcgctg gtttggagat agcaggtacg cactgaagaa cggccaactc aaatggtacg   2820

aagactataa gcgaggcaac ttcccaccag ggctactggt cattgcccct ggcaaccggg   2880

agctcctgca ggactattac atgacacaca agatgctgta tgaagaggac ctgcagaacc   2940

tctgtgacaa gacccagatg agctcccagc aggtcaagca gtggtttgct gagaaaatgg   3000

gggaggagac cagagccgtg gcagacacag gcagtgagga ccagggccct ggtactggtg   3060

agctcacagc agttcacaaa gggatgggtg acacctattc agaggtgtct gagaacagtg   3120

agtcgtggga gccccgtgtc cctgaggcca gctcagagcc ctttgacaca tcgagtcccc   3180

aggctggacg tcagctcgaa acagactgaa tttgatctga ttaatgtgaa ggactggcca   3240

gtctgggaaa ccgcctgcca cgtggaagag ccaaacccga ctctctgctg ccacatgccg   3300

ttcccatgcc cggctgctgg gcacctggga gagcttccag aatcctcgca gacagcccag   3360

agcctgccgc taccctcggc ctgcccacca ccaagcaagc agcaagcaag atggggttct   3420

catcagttct tcctcccaca atgtaggacc tttcctttac cttccaatgg ataaaatagt   3480

tcagagttca tagtcatatt catagacaca gaatcaagct tttaacatat acatccacct   3540

ctatatgtta aataaaacat cagattatca acactgtcat tacgtagaaa ctttggttag   3600

ccaagcagtg cattgtcagt tacgtcatct ctaaaaatga cctgtgtctg ttctctgggg   3660

attgctgggt cacaggtgcc cctcaccttc cacagtcagg cagggaagtt ataggcacaa   3720

agctacgtct ggaacccctt tgtgccccct ttgtgttcct caaggaagca gtacctttga   3780

agagatctct gctgcattaa gtgatgaccg gctacgtttc atgtcaggct tgctttgcct   3840

tgtgggctac tcagtgcaga acctgctgta accctcagtt caaaaaatgg actggcaatg   3900

tgattagcgt tggatgcttt accattctct ttagttgtta ccgtaattct gctttttcat   3960

gggagtttga atcatggacc ataacttttc agttatcaga tcaactaaag aaacatttgt   4020

tgttaagcct aatgtgctga cctatgtgcc tgcatttttt ttttaatcta gacatgtttg   4080

gagtgagaga aagatggaaa aaagacatgg ggtagggacg taagtggaaa tctatagcca   4140

cagcctgaag ctttgaccac tgcggttttc agagcccttt ctccacactc atttcagagc   4200

ctcctatggt ttgggaagga ataacacact ggcccattag taagggtgaa ggctggaggg   4260

atttgttgac ttcttggaat tatcagaggt agggtggtct ttagcacaaa gacttgcatg   4320

cagagatccc tggcagaaca cccagagtgc ccgtggctcc caccccaggg tctggccggt   4380

gtgctggatg catgcccaag ggtgctgggc atcactggtc cttgtgagga tgcttttaaa   4440

gttttatatt tatgtcccca aacttggaaa caagaactct actttagcct aaccctcatg   4500

tccttttttg aattgagaaa attacaggaa atggtgcctt tgaaaattag aaaacttgct   4560

tacagagctg ttctaaatgg taaatcctca atttccccaa gaccggttgc tctgagagta   4620

gctggtaaag aggggcgaac taaagacctg tccacctgta gctccgctca tttcttagaa   4680

accacctgct tcccagagtg ccaagccaca agtaccaggc ttcgtgggca cagacacctc   4740

ctgggctggg cagagtgaca gtgctagaag accccagaga gagggcaagg gctttgggca   4800

agaagcactg gtggtgtttt agggaccgtc cttctcccct acccagggaa ctggacctgg   4860

cagggcaccg tgctcatgtg gctccaagga caagcatggc ggtggcccct tctgccttcc   4920

aggagaggtc ttgcttttga aaccaaaatc atgttcttct aaagtgtcat cttctgccct   4980

ccctgtccca atagggacca catcttattt gtctcaaaca gggacttgtg agtacttggc   5040

aagttttgca gcctattttt gtattcttaa tttggggagt aaagatgttt ggtctcaaaa   5100

acctttgagg aattgccaag aatggcgagt gattgctttc cttcagagaa cagacacttg   5160

gaatttctcc ttttagtgtt tatatacgtg cagattaatt tatatatata tatatacaca   5220

cacacatata cagtataaat actcatttga ttctcgtaaa acgcgcatct ggcgtgtgca   5280

gttgagaaac ttggtggcac atgggtgttg ggggagtagc ctgtgttgga gggacaccag   5340

tgcactaggc agctggggcg gcccaggctg aagccatctc cgggtgtctg agaaaccacc   5400

cagtgcctca cctccagatc ctgctggcat cacctccaga gccctgcatg cactggctga   5460

agagttggtc tgtggagagg attttcttgg ttacttgtat tcacggttaa tttacaaccc   5520

aaacagcaaa acacagttgg tggacaagtt catgcaggac ctacagtgac ccagccatgg   5580

gcactagctc atctttcagg tggaaaagta cagtgctgcc tgccctggta tgtttttctt   5640

atagatgtta gccctgccca acagccaggg ctacactaca aaaggcaaga atgcccatgt   5700

aaggagccca gcagtctgga cagatccttc ttcctctgct gttggatgag agtgagtgag   5760

tatgctctgg accttatcct tgaaagatga tcaaaagcga tgatgaggga ggcagtcatc   5820

acgcaggtgc ttaaagggac attgtaggag gtactcaagg gtttgggggc aaaaccctga   5880

atccagccag tcgtgcacag agacacaccc acactagccc agtggcagtg ggggatgtgg   5940

gatggcagca gccaggtatg tagccctgtc acaggacagc tcactgtggt tttgcacact   6000

gcctaagggt taaattgtgt tgttgccttc agtagaaggc atttgtgggc tgcagagttg   6060

agagttgggt gaggttagtc tctcctgaag aaaaagccta taaaaagtgg ctaatcttat   6120

cccttttctc tgtatgcagt tggactcgtc agagatagta aaatcatctt ttagtgtttt   6180

tttgttgctg atgtcttgta cccatttgtt ttttacatgg ggttgtagat cgagttctca   6240

aaggtgaaac cagatgatca ttctgataaa ggaaatttaa atttgataca tatgctttgt   6300

atattttgat tacttgtttt cgtttttgac tataaaggag cttttttatt ttgggagggg   6360

aggagtgtca tttttgagaa tcttgggttc ctgaaaaaga acgccctagt tggatggctt   6420

gccagggcct tggggtttgg tagtgattgt acaacttaaa gctcctttct cttggctgag   6480

tgacaggtgg ctgttcaggt ggaccaaagc accttgacac aaggactcca cactgtgctc   6540

tctagtagca caaggaggaa gttggacaga acattgggta gtgccttgcg ggctcacaca   6600

tgtactagtg gtctcatctc cagctagcct tgggaggccg tcccaccagg aaatctctct   6660

attccgtagc ctgagatgtg cccttgtggg ttttatcctg ctcagtcagt ggcctagggg   6720

caggtcctgt gttctctccc tctctctcct ggctctggga catctgtccc tggctgcctt   6780

tcatggagga aggacactgg cctttctggt tggatgctgt gtggatgctc tctgcttgag   6840

cctcgtggtc tcttgtctct ttttggacca atatcctcag attggtgcag ctttttcagt   6900

tcagatatca caccccaagt ggataaaggc aacttgcagg agaggagagc cagccaagaa   6960

gaaaatttta aaaccaaacc tcgtttagga ttttcctaaa gtcatcttct cttttttctt   7020

gctcagagtt tacctgggag atttcaccag tttgactcac catttgcaga tgtgcttttg   7080

tattaaattt aaattttcac atatcacatc cattctcaag gtagttatat gctggagaag   7140

aaaaatcctc tagacacatg aaggcccaca tagtcaagtc ttccagggca aagccagcag   7200

cccacccagg tcaggtagcc agcagggctc agttcccctc actccagaca cggaccctcc   7260

tcttcagggt ctcttgaccc agcttccttc tctcctttta cctgagagca cagacctctc   7320

tcagccagcc tgcccagacc acggggggct actcccatgt agtttgggga gcacttgatc   7380

tcagaaaagc tccattgtct gagcaaatgg gcagttgtgg agctcaagcc tttctcctgt   7440

gctcaagtcc cttccccaag caaggcttca acctcatcta cccaccatgt agttttctct   7500

ggccatttaa gtggggcggc agggacatgg ttgggccatg ccacaccagg gctggtgagg   7560

caaccagttt tgattttgac agagtggctg gaggaaaagt ggcaatcaag gtgctgcttg   7620

gtttgctctg agtgcaaatg gaaccaacag gtttctgctg caatctgtgt gttcccagtg   7680

ccaggtcaca ccaggagggg tggggcaggg ctaaccaagt ggtctctgaa ctcaccgagc   7740

gtctgcactt ggttgtgaag ttaatgggag tacagagagc gtctggcctt ggagaggggt   7800

tgagagcctc ctttttggtt cttcattcct gagctcttgc ctgcccacaa atctgacctc   7860

tttgaatggg gacgcagtcc ttcaacagag aagtttctat ggcaaagaag tttctattta   7920

gctctagatc cagcagagtc atccattcta actgccctga agtctagagc aggggaggga   7980

acccagaggc tggggatgag actaggcaga ccctggttac catatggaca aggacagggg   8040

aaagcacccc cttcctcaat ttctgaaagt tctatctttg ggttcgcagg actttgagga   8100

tgataaagaa catataggta ctagcttgtt gttgctggtc caaagcttcc acagccctga   8160

gaatttggct ttcgtggctg ctctggcagc tgagcgaagg gaggaaggca gccgctctgg   8220

tggggactct aggcaccttc cctgctgtcc acttggatag gcggtgagcc ccagggtact   8280

gagaggagcc tgagcattta cctgccatta gtgcctcttc cttcaggaga ctggcttgaa   8340

acgtgtgttc atgtgcgcgt gcacacacac acatgagcac ctgtatgtgt taatgaatag   8400

tttttcttgg ttaatgcttt ttaacttctg ttcctttccg taagtggatg attcaaaatt   8460

aacgtgactt ggctgggcgc agtggctcac acctgtaatc ccagcacttt gggaggccaa   8520

gggaggcgga tcacctgagg tcaggagttc gagaccagcc tgatcggcat ggtgaaaccc   8580

cgtttctact aaaaatacaa aaattagccg ggcgtggtgg tgcgcgcctg taatcccagc   8640

tactcaggag gctgaggaag gagaatcact tgaacccggg aggtggaggt tgcagtgagc   8700

tgagatcgtg ccactgcact ccagcctggg cgacagagcg aaactccgtc tcaaaaaaaa   8760

aaaaaaaact taatgtgact ggagttaaaa gtgaaatgtc aggttgttta gtcactgaat   8820

agagagctac aagtgcttgg tctttcccaa gaatcaaacc tgagtagaaa tacatttaaa   8880

agaaaaatct acatggtacc tatgaatcct gtaatttgtt tagggagatc ttgtcactca   8940

tccctggttc ctgcccatac tgtttggtct cgttcttgca gtttgcttgg aacagggcca   9000

gagccccaca tgagattgtc agcaggagtg aggagcgcca gtccctactc ctcagcaggg   9060

acccagcaca gcaatccggt tgttctcggt tagactgggt cggggccagg ggagaagcag   9120

tcacccctgt gtagagggtt cccgctgtgc ttctgagcag ttgctttgtt cagaagtgtt   9180

aggagggtca gattgtgcca taattgttat taaagagaaa acacgcccac cttcctttct   9240

cccctgctgg ccattgttca ttgagtttta ctgagggcag cctttgtgga agtcagggag   9300

gttgccaaag gcctgtagat gcctcctgac aaggtcttga ttcctggttt tctagcaccc   9360

atttgcattt tggtcttcag cacaaagcct tgttccctgt ggccggactt ctgggcaata   9420

agactgggga gtgactgttg agcagtctgc tgtcaggaga gatggctgaa aaggtgatca   9480

tcttggtgct aaacaagtaa gaggcaactg ccctgttttt gtttgttttg aggcacaatg   9540

aaactttagc caaactctgc aagagggtcc catctcctgc catggccagg tgtgagagac   9600

caaaccgaga aaacagcata ctctatcact taagccttgg gtagaatggg aattctttac   9660

cctgggtaaa cgttttaaca aaaaaatgga acttaacttc ggtttggact gtggtcgtgc   9720

tgaggcagga gtggggttgc cctcttgggg ctgaatctcc aggcctcacg aggtcccctg   9780

tggggatgct gctatttcta agatgcaaat tgcacatttc ctagattttg tatctgtgga   9840

tttggataag ggaggggaac acggacaaat tgcttgtaca atttgaaatg ggcctcaatg   9900

gtacttcaaa ccttttgatt attcctaaat aaaaacataa atatatttca c            9951


<210>  10116
<211>  956
<212>  PRT
<213>  Homo sapiens

<400>  10116

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Val Lys 
865                 870                 875                 880


Gln Trp Phe Ala Glu Lys Met Gly Glu Glu Thr Arg Ala Val Ala Asp 
                885                 890                 895


Thr Gly Ser Glu Asp Gln Gly Pro Gly Thr Gly Glu Leu Thr Ala Val 
            900                 905                 910


His Lys Gly Met Gly Asp Thr Tyr Ser Glu Val Ser Glu Asn Ser Glu 
        915                 920                 925


Ser Trp Glu Pro Arg Val Pro Glu Ala Ser Ser Glu Pro Phe Asp Thr 
    930                 935                 940


Ser Ser Pro Gln Ala Gly Arg Gln Leu Glu Thr Asp 
945                 950                 955


<210>  10117
<211>  498
<212>  DNA
<213>  Homo sapiens

<400>  10117
ggatgactct gctggatcta gagctaaata gaaacttctt tgccatagaa acttctctgt     60

tgaaggactg cgtccccatt caaagaggtc agatttgtgg gcaggcaaga gctcaggaat    120

gaagaaccaa aaaggaggct ctcaacccct ctccaaggcc agacgctctc tgtactccca    180

ttaacttcac aaccaagtgc agacgctcga ccaactcttc agccagtgca tgcagggctc    240

tggaggtgat gccagcagga tctggaggat ctcgctctgt aacccaggct ctggaatgca    300

gtggcacaac cacggctcac tgcagtctca acctcctggg ctcaactgat ccccccactt    360

cagcctcctg agtagctggg actacagagg acactggagg tgaagaagga agctcttgac    420

tctcctaaag ctgatcccaa agtgaaggct ttgaaggcca agaaggcagt gctgaaaggc    480

atccacacag ccaccaag                                                  498


<210>  10118
<211>  40
<212>  PRT
<213>  Homo sapiens

<400>  10118

Met Pro Ala Gly Ser Gly Gly Ser Arg Ser Val Thr Gln Ala Leu Glu 
1               5                   10                  15


Cys Ser Gly Thr Thr Thr Ala His Cys Ser Leu Asn Leu Leu Gly Ser 
            20                  25                  30


Thr Asp Pro Pro Thr Ser Ala Ser 
        35                  40


<210>  10119
<211>  3288
<212>  DNA
<213>  Homo sapiens

<400>  10119
gtggtgttgc aagatgccag catggaggcc cagcccgctg agaccttgcc tgaaggaccc     60

cagcaggatc tgcccccaga agcatctgct gccagcagtg aggcagcaca gaaccccagc    120

agtactgatg gctctacact ggccaatggg catcggagca ctttagatgg ctatttatat    180

tcctgtaaat actgcgattt cagatcccat gacatgaccc aatttgtggg acatatgaac    240

tcagagcaca cagactttaa taaagaccca acctttgtat gcagtgggtg cagttttctg    300

gcaaaaaccc ctgaggggct ttccttgcac aatgccacat gtcactccgg ggaagccagc    360

tttgtgtgga acgtggccaa gccagacaat catgtggttg tggagcagag catccctgag    420

agcaccagca ctcctgacct agcgggtgag cccagtgctg aaggggctga tggacaggca    480

gaaatcatca ttaccaaaac tccaatcatg aagataatga aaggcaaagc tgaagccaaa    540

aaaattcata cactcaagga gaatgtccct agccagcctg tgggtgaggc cttaccaaag    600

ctgtcgactg gagaaatgga ggtgagagag ggggaccatt ccttcatcaa tggggcagtt    660

ccagtcagcc aggcatctgc cagctctgca aaaaaccccc atgccgccaa cgggcccctg    720

ataggaacag tgccagtttt gccagctggc atagcacagt tcctctccct ccagcagcag    780

cccccagtgc atgcccaaca ccatgtccac cagccactgc ccacggccaa ggcccttccc    840

aaagtgatga tccccctgag cagcattcca acgtacaatg cagccatgga ctctaacagc    900

ttcctgaaga actccttcca caagttcccc taccccacca aagccgagct ctgctatttg    960

actgtggtga ccaagtatcc agaagaacag ctcaagatct ggttcacagc ccaaaggctg   1020

aagcagggga tcagctggtc ccctgaggag attgaggatg cccggaaaaa gatgttcaat   1080

acagtcatcc agtctgtgcc tcagcccaca attacggttc taaatacccc actcgtcgcc   1140

agtgctggca atgtccagca tctcatccag gccgctcttc caggtcacgt tgtggggcag   1200

ccagagggta caggaggggg acttctggtc actcagccat tgatggccaa tgggttgcaa   1260

gcaacaagtt cccctctccc cctcacggtg acatccgtcc ccaagcagcc aggtgtggca   1320

cccattaaca ctgtgtgttc aaatacaacg tcagctgtga aggtggtcaa tgcggcccag   1380

tcgctcctca cggcctgccc cagcataacc tcccaagcct tccttgatgc tagcatctac   1440

aaaaataaga aatctcatga acagctgtca gctctgaaag ggagcttctg tcggaaccag   1500

ttcccagggc agagcgaagt tgaacatctc acaaaagtga cgggcctcag taccagagag   1560

gtgcggaaat ggttcagtga tcgtagatac cactgccgga acttgaaggg ctccagagcg   1620

atgatacctg gagatcacag ttccatcatc attgactctg tgccagaggt gtccttctcc   1680

ccatcgtcca aggtccctga ggtaacctgc attccgacaa cagccacact agcaacccac   1740

ccttctgcca aacgacaatc ttggcaccag actcctgact tcacaccaac caaatacaag   1800

gagagagccc ctgagcagct cagagccctg gagagcagtt ttgcacaaaa ccctcttcct   1860

cttgatgagg aactggaccg cctgagaagt gaaaccaaaa tgacccgacg agaaattgat   1920

agctggtttt cagagagacg gaaaaaagtg aatgctgagg agaccaagaa ggctgaggag   1980

aatgcctctc aggaggaaga ggaggctgct gaggatgagg gtggagaaga ggatttggcc   2040

agtgagctaa gggtctctgg tgaaaatggc tctctggaaa tgcccagcag ccatatcttg   2100

gcagagcgca aagtcagccc cattaaaatc aacctgaaga acctgagggt cactgaagcc   2160

aatggcagga acgagattcc agggctgggt gcctgtgacc ctgaggatga tgagtcaaac   2220

aaactggcag agcagctccc aggcaaagtg agctgcaaaa agactgccca gcagcggcac   2280

ttgctgcggc agctctttgt ccagacacag tggccaagca accaggacta tgactccatc   2340

atggcccaga cgggtctgcc acggccagag gtggtgcgct ggtttggaga tagcaggtac   2400

gcactgaaga acggccaact caaatggtac gaagactata agcgaggcaa cttcccacca   2460

gggctactgg tcattgcccc tggcaaccgg gagctcctgc aggactatta catgacacac   2520

aagatgctgt atgaagagga cctgcagaac ctctgtgaca agacccagat gagctcccag   2580

caggtcaagc agtggtttgc tgagaaaatg ggggaggaga ccagagccgt ggcagacaca   2640

ggcagtgagg accagggccc tggtactggt gagctcacag cagttcacaa agggatgggt   2700

gacacctatt cagaggtgtc tgagaacagt gagtcgtggg agccccgtgt ccctgaggcc   2760

agctcagagc cctttgacac atcgagtccc caggctggac gtcagctcgg ttcctggtca   2820

ctgagttccc agcctctccc ttccctcctt accctttgac atttgtgttc tcattagaga   2880

ccccatcaga gggcagccag aagctcagaa acagactgaa tttgatctga ttaatgtgaa   2940

ggactggcca gtctgggaaa ccgcctgcca cgtggaagag ccaaacccga ctctctgctg   3000

ccacatgccg ttcccatgcc cggctgctgg gcacctggga gagcttccag aatcctcgca   3060

gacagcccag agcctgccgc taccctcggc ctgcccacca ccaagcaagc agcaagcaag   3120

atggggttct catcagttct tcctcccaca atgtaggacc tttcctttac cttccaatgg   3180

ataaaatagt tcagagttca tagtcatatt catagacaca gaatcaagct tttaacatat   3240

acatccacct ctatatgtta aataaaacat cagattatca acactgtc                3288


<210>  10120
<211>  945
<212>  PRT
<213>  Homo sapiens

<400>  10120

Met Glu Ala Gln Pro Ala Glu Thr Leu Pro Glu Gly Pro Gln Gln Asp 
1               5                   10                  15


Leu Pro Pro Glu Ala Ser Ala Ala Ser Ser Glu Ala Ala Gln Asn Pro 
            20                  25                  30


Ser Ser Thr Asp Gly Ser Thr Leu Ala Asn Gly His Arg Ser Thr Leu 
        35                  40                  45


Asp Gly Tyr Leu Tyr Ser Cys Lys Tyr Cys Asp Phe Arg Ser His Asp 
    50                  55                  60


Met Thr Gln Phe Val Gly His Met Asn Ser Glu His Thr Asp Phe Asn 
65                  70                  75                  80


Lys Asp Pro Thr Phe Val Cys Ser Gly Cys Ser Phe Leu Ala Lys Thr 
                85                  90                  95


Pro Glu Gly Leu Ser Leu His Asn Ala Thr Cys His Ser Gly Glu Ala 
            100                 105                 110


Ser Phe Val Trp Asn Val Ala Lys Pro Asp Asn His Val Val Val Glu 
        115                 120                 125


Gln Ser Ile Pro Glu Ser Thr Ser Thr Pro Asp Leu Ala Gly Glu Pro 
    130                 135                 140


Ser Ala Glu Gly Ala Asp Gly Gln Ala Glu Ile Ile Ile Thr Lys Thr 
145                 150                 155                 160


Pro Ile Met Lys Ile Met Lys Gly Lys Ala Glu Ala Lys Lys Ile His 
                165                 170                 175


Thr Leu Lys Glu Asn Val Pro Ser Gln Pro Val Gly Glu Ala Leu Pro 
            180                 185                 190


Lys Leu Ser Thr Gly Glu Met Glu Val Arg Glu Gly Asp His Ser Phe 
        195                 200                 205


Ile Asn Gly Ala Val Pro Val Ser Gln Ala Ser Ala Ser Ser Ala Lys 
    210                 215                 220


Asn Pro His Ala Ala Asn Gly Pro Leu Ile Gly Thr Val Pro Val Leu 
225                 230                 235                 240


Pro Ala Gly Ile Ala Gln Phe Leu Ser Leu Gln Gln Gln Pro Pro Val 
                245                 250                 255


His Ala Gln His His Val His Gln Pro Leu Pro Thr Ala Lys Ala Leu 
            260                 265                 270


Pro Lys Val Met Ile Pro Leu Ser Ser Ile Pro Thr Tyr Asn Ala Ala 
        275                 280                 285


Met Asp Ser Asn Ser Phe Leu Lys Asn Ser Phe His Lys Phe Pro Tyr 
    290                 295                 300


Pro Thr Lys Ala Glu Leu Cys Tyr Leu Thr Val Val Thr Lys Tyr Pro 
305                 310                 315                 320


Glu Glu Gln Leu Lys Ile Trp Phe Thr Ala Gln Arg Leu Lys Gln Gly 
                325                 330                 335


Ile Ser Trp Ser Pro Glu Glu Ile Glu Asp Ala Arg Lys Lys Met Phe 
            340                 345                 350


Asn Thr Val Ile Gln Ser Val Pro Gln Pro Thr Ile Thr Val Leu Asn 
        355                 360                 365


Thr Pro Leu Val Ala Ser Ala Gly Asn Val Gln His Leu Ile Gln Ala 
    370                 375                 380


Ala Leu Pro Gly His Val Val Gly Gln Pro Glu Gly Thr Gly Gly Gly 
385                 390                 395                 400


Leu Leu Val Thr Gln Pro Leu Met Ala Asn Gly Leu Gln Ala Thr Ser 
                405                 410                 415


Ser Pro Leu Pro Leu Thr Val Thr Ser Val Pro Lys Gln Pro Gly Val 
            420                 425                 430


Ala Pro Ile Asn Thr Val Cys Ser Asn Thr Thr Ser Ala Val Lys Val 
        435                 440                 445


Val Asn Ala Ala Gln Ser Leu Leu Thr Ala Cys Pro Ser Ile Thr Ser 
    450                 455                 460


Gln Ala Phe Leu Asp Ala Ser Ile Tyr Lys Asn Lys Lys Ser His Glu 
465                 470                 475                 480


Gln Leu Ser Ala Leu Lys Gly Ser Phe Cys Arg Asn Gln Phe Pro Gly 
                485                 490                 495


Gln Ser Glu Val Glu His Leu Thr Lys Val Thr Gly Leu Ser Thr Arg 
            500                 505                 510


Glu Val Arg Lys Trp Phe Ser Asp Arg Arg Tyr His Cys Arg Asn Leu 
        515                 520                 525


Lys Gly Ser Arg Ala Met Ile Pro Gly Asp His Ser Ser Ile Ile Ile 
    530                 535                 540


Asp Ser Val Pro Glu Val Ser Phe Ser Pro Ser Ser Lys Val Pro Glu 
545                 550                 555                 560


Val Thr Cys Ile Pro Thr Thr Ala Thr Leu Ala Thr His Pro Ser Ala 
                565                 570                 575


Lys Arg Gln Ser Trp His Gln Thr Pro Asp Phe Thr Pro Thr Lys Tyr 
            580                 585                 590


Lys Glu Arg Ala Pro Glu Gln Leu Arg Ala Leu Glu Ser Ser Phe Ala 
        595                 600                 605


Gln Asn Pro Leu Pro Leu Asp Glu Glu Leu Asp Arg Leu Arg Ser Glu 
    610                 615                 620


Thr Lys Met Thr Arg Arg Glu Ile Asp Ser Trp Phe Ser Glu Arg Arg 
625                 630                 635                 640


Lys Lys Val Asn Ala Glu Glu Thr Lys Lys Ala Glu Glu Asn Ala Ser 
                645                 650                 655


Gln Glu Glu Glu Glu Ala Ala Glu Asp Glu Gly Gly Glu Glu Asp Leu 
            660                 665                 670


Ala Ser Glu Leu Arg Val Ser Gly Glu Asn Gly Ser Leu Glu Met Pro 
        675                 680                 685


Ser Ser His Ile Leu Ala Glu Arg Lys Val Ser Pro Ile Lys Ile Asn 
    690                 695                 700


Leu Lys Asn Leu Arg Val Thr Glu Ala Asn Gly Arg Asn Glu Ile Pro 
705                 710                 715                 720


Gly Leu Gly Ala Cys Asp Pro Glu Asp Asp Glu Ser Asn Lys Leu Ala 
                725                 730                 735


Glu Gln Leu Pro Gly Lys Val Ser Cys Lys Lys Thr Ala Gln Gln Arg 
            740                 745                 750


His Leu Leu Arg Gln Leu Phe Val Gln Thr Gln Trp Pro Ser Asn Gln 
        755                 760                 765


Asp Tyr Asp Ser Ile Met Ala Gln Thr Gly Leu Pro Arg Pro Glu Val 
    770                 775                 780


Val Arg Trp Phe Gly Asp Ser Arg Tyr Ala Leu Lys Asn Gly Gln Leu 
785                 790                 795                 800


Lys Trp Tyr Glu Asp Tyr Lys Arg Gly Asn Phe Pro Pro Gly Leu Leu 
                805                 810                 815


Val Ile Ala Pro Gly Asn Arg Glu Leu Leu Gln Asp Tyr Tyr Met Thr 
            820                 825                 830


His Lys Met Leu Tyr Glu Glu Asp Leu Gln Asn Leu Cys Asp Lys Thr 
        835                 840                 845


Gln Met Ser Ser Gln Gln Val Lys Gln Trp Phe Ala Glu Lys Met Gly 
    850                 855                 860


Glu Glu Thr Arg Ala Val Ala Asp Thr Gly Ser Glu Asp Gln Gly Pro 
865                 870                 875                 880


Gly Thr Gly Glu Leu Thr Ala Val His Lys Gly Met Gly Asp Thr Tyr 
                885                 890                 895


Ser Glu Val Ser Glu Asn Ser Glu Ser Trp Glu Pro Arg Val Pro Glu 
            900                 905                 910


Ala Ser Ser Glu Pro Phe Asp Thr Ser Ser Pro Gln Ala Gly Arg Gln 
        915                 920                 925


Leu Gly Ser Trp Ser Leu Ser Ser Gln Pro Leu Pro Ser Leu Leu Thr 
    930                 935                 940


Leu 
945


<210>  10121
<211>  861
<212>  DNA
<213>  Homo sapiens

<400>  10121
gtgaaaagac ctagatggta gaaggcaagc agtggaatgt gtctgggtat ccgagaaata     60

tacagaaagc acttaagaga acttaatcat ttttttctcc ctttccttag attgaatagg    120

gaaaacctgc tttctgcaaa caactgaaaa agctgcattt agaaactgtt tctttggccc    180

tcatcgagaa gctggaactt gtattgttag gccccttatg ggacaagctc tcaactgctg    240

atcacccagt gattgtcacc atggccagca agaggaaatc caccacacca tgcatgatcc    300

cagtgaagac tgtggtgttg caagatgcca gcatggaggc ccagcccgct gagaccttgc    360

ctgaaggacc ccagcaggat ctgcccccag aagcatctgc tgccagcagt gaggcagcac    420

agaaccccag cagtatcaga gccctttgac acatcgagtc cccaggctgg acgtcagctc    480

gaaacagact gaatttgatc tgattaatgt gaaggactgg ccagtctggg aaaccgcctg    540

ccacgtggaa gagccaaacc cgactctctg ctgccacatg ccgttcccat gcccggctgc    600

tgggcacctg ggagagcttc cagaatcctc gcagacagcc cagagcctgc cgctaccctc    660

ggcctgccca ccaccaagca agcagcaagc aagatggggt tctcatcagt tcttcctccc    720

acaatgtagg acctttcctt taccttccaa tggataaaat agttcagagt tcatagtcat    780

attcatagac acagaatcaa gcttttaaca tatacatcca cctctatatg ttaaataaaa    840

catcagatta tcaacactgt c                                              861


<210>  10122
<211>  62
<212>  PRT
<213>  Homo sapiens

<400>  10122

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Ile Arg Ala Leu 
    50                  55                  60


<210>  10123
<211>  3477
<212>  DNA
<213>  Homo sapiens

<400>  10123
aagttctttc cagctctgga caggaaaaca tgaaaacaga tgatcccaag gaggactgaa     60

atgcaactgc agaagcaaca tgtgaccttt tagagatgct tgtgggactg cataaagtga    120

agagggaaac tggaaaaaaa caatgaagct aatcccgaac tcctggcctc aaatgatctt    180

cctaccttgg cttcccaaag tgctgggatt acagacgtga gctgctgtgc ctggccaaga    240

cttaattttg aatgacattg ggactattgc caaaaatcaa atccatcttc atgttgtcca    300

cttctcagcc ttaattgaat agggaaaacc tgctttctgc aaacaactga aaaagctgca    360

tttagaaact gtttctttgg ccctcatcga gaagctggaa cttgtattgt taggcccctt    420

atgggacaag ctctcaactg ctgatcaccc agtgattgtc accatggcca gcaagaggaa    480

atccaccaca ccatgcatga tcccagtgaa gactgtggtg ttgcaagatg ccagcatgga    540

ggcccagccc gctgagacct tgcctgaagg accccagcag gatctgcccc cagaagcatc    600

tgctgccagc agtgaggcag cacagaaccc cagcagtact gatggctcta cactggccaa    660

tgggcatcgg agcactttag atggctattt atattcctgt aaatactgcg atttcagatc    720

ccatgacatg acccaatttg tgggacatat gaactcagag cacacagact ttaataaaga    780

cccaaccttt gtatgcagtg ggtgcagttt tctggcaaaa acccctgagg ggctttcctt    840

gcacaatgcc acatgtcact ccggggaagc cagctttgtg tggaacgtgg ccaagccaga    900

caatcatgtg gttgtggagc agagcatccc tgagagcacc agcactcctg acctagcggg    960

tgagcccagt gctgaagggg ctgatggaca ggcagaaatc atcattacca aaactccaat   1020

catgaagata atgaaaggca aagctgaagc caaaaaaatt catacactca aggagaatgt   1080

ccctagccag cctgtgggtg aggccttacc aaagctgtcg actggagaaa tggaggtgag   1140

agagggggac cattccttca tcaatggggc agttccagtc agccaggcat ctgccagctc   1200

tgcaaaaaac ccccatgccg ccaacgggcc cctgatagga acagtgccag ttttgccagc   1260

tggcatagca cagttcctct ccctccagca gcagccccca gtgcatgccc aacaccatgt   1320

ccaccagcca ctgcccacgg ccaaggccct tcccaaagtg atgatccccc tgagcagcat   1380

tccaacgtac aatgcagcca tggactctaa cagcttcctg aagaactcct tccacaagtt   1440

cccctacccc accaaagccg agctctgcta tttgactgtg gtgaccaagt atccagaaga   1500

acagctcaag atctggttca cagcccaaag gctgaagcag gggatcagct ggtcccctga   1560

ggagattgag gatgcccgga aaaagatgtt caatacagtc atccagtctg tgcctcagcc   1620

cacaattacg gttctaaata ccccactcgt cgccagtgct ggcaatgtcc agcatctcat   1680

ccaggccgct cttccaggtc acgttgtggg gcagccagag ggtacaggag ggggacttct   1740

ggtcactcag ccattgatgg ccaatgggtt gcaagcaaca agttcccctc tccccctcac   1800

ggtgacatcc gtccccaagc agccaggtgt ggcacccatt aacactgtgt gttcaaatac   1860

aacgtcagct gtgaaggtgg tcaatgcggc ccagtcgctc ctcacggcct gccccagcat   1920

aacctcccaa gccttccttg atgctagcat ctacaaaaat aagaaatctc atgaacagct   1980

gtcagctctg aaagggagct tctgtcggaa ccagttccca gggcagagcg aagttgaaca   2040

tctcacaaaa gtgacgggcc tcagtaccag agaggtgcgg aaatggttca gtgatcgtag   2100

ataccactgc cggaacttga agggctccag agcgatgata cctggagatc acagttccat   2160

catcattgac tctgtgccag aggtgtcctt ctccccatcg tccaaggtcc ctgaggtaac   2220

ctgcattccg acaacagcca cactagcaac ccacccttct gccaaacgac aatcttggca   2280

ccagactcct gacttcacac caaccaaata caaggagaga gcccctgagc agctcagagc   2340

cctggagagc agttttgcac aaaaccctct tcctcttgat gaggaactgg accgcctgag   2400

aagtgaaacc aaaatgaccc gacgagaaat tgatagctgg ttttcagaga gacggaaaaa   2460

agtgaatgct gaggagacca agaaggctga ggagaatgcc tctcaggagg aagaggaggc   2520

tgctgaggat gagggtggag aagaggattt ggccagtgag ctaagggtct ctggtgaaaa   2580

tggctctctg gaaatgccca gcagccatat cttggcagag cgcaaagtca gccccattaa   2640

aatcaacctg aagaacctga gggtcactga agccaatggc aggaacgaga ttccagggct   2700

gggtgcctgt gaccctgagg atgatgagtc aaacaaactg gcagagcagc tcccaggcaa   2760

agtgagctgc aaaaagactg cccagcagcg gcacttgctg cggcagctct ttgtccagac   2820

acagtggcca agcaaccagg actatgactc catcatggcc cagacgggtc tgccacggcc   2880

agaggtggtg cgctggtttg gagatagcag gtacgcactg aagaacggcc aactcaaatg   2940

gtacgaagac tataagcgag gcaacttccc accagggcta ctggtcattg cccctggcaa   3000

ccgggagctc ctgcaggact attacatgac acacaagatg ctgtatgaag aggacctgca   3060

gaacctctgt gacaagaccc agatgagctc ccagcagaaa cagactgaat ttgatctgat   3120

taatgtgaag gactggccag tctgggaaac cgcctgccac gtggaagagc caaacccgac   3180

tctctgctgc cacatgccgt tcccatgccc ggctgctggg cacctgggag agcttccaga   3240

atcctcgcag acagcccaga gcctgccgct accctcggcc tgcccaccac caagcaagca   3300

gcaagcaaga tggggttctc atcagttctt cctcccacaa tgtaggacct ttcctttacc   3360

ttccaatgga taaaatagtt cagagttcat agtcatattc atagacacag aatcaagctt   3420

ttaacatata catccacctc tatatgttaa ataaaacatc agattatcaa cactgtc      3477


<210>  10124
<211>  969
<212>  PRT
<213>  Homo sapiens

<400>  10124

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Lys Gln 
865                 870                 875                 880


Thr Glu Phe Asp Leu Ile Asn Val Lys Asp Trp Pro Val Trp Glu Thr 
                885                 890                 895


Ala Cys His Val Glu Glu Pro Asn Pro Thr Leu Cys Cys His Met Pro 
            900                 905                 910


Phe Pro Cys Pro Ala Ala Gly His Leu Gly Glu Leu Pro Glu Ser Ser 
        915                 920                 925


Gln Thr Ala Gln Ser Leu Pro Leu Pro Ser Ala Cys Pro Pro Pro Ser 
    930                 935                 940


Lys Gln Gln Ala Arg Trp Gly Ser His Gln Phe Phe Leu Pro Gln Cys 
945                 950                 955                 960


Arg Thr Phe Pro Leu Pro Ser Asn Gly 
                965


<210>  10125
<211>  4145
<212>  DNA
<213>  Homo sapiens

<400>  10125
agccgtcaaa ggcagcaaat agactgaatg aaagatgagc ttctgccttt atatccttct     60

ctcctgctac ccaactcatt gtggtgaagg aaaaagaaaa cgcgggtgga gactgcacta    120

tatgcttagg actgaaatgc aactgcagaa gcaacatgtg accttttaga gatgcttgtg    180

ggactgcata aagtgaagag ggaaactgga aaaaaacaat gaacatttat caccatccag    240

ccactgtaga taaatttgat tggctgtctc cctgccttcc cttcacaccc agtaccttcc    300

ctgcctgaaa tcctcattga gggcaagaac tttatcccca ggatctaaac cagtgctgga    360

caatagatgc tcatcccttc cataggaaac agggaatgtt tgtttctgtc ttctggtagg    420

agaaggattg gtcccacccc cagctccagg gatggatctt gattgtttaa gcccagtcag    480

tgattctaac ccatggacca agaccctgcc ttggagattg gggaacaggt gttggaaggg    540

ctctattttg gcaaagaatg gattatttat gtgagcatat ttccgcaaag ctaatcccga    600

actcctggcc tcaaatgatc ttcctacctt ggcttcccaa agtgctggga ttacagacgt    660

gagctgctgt gcctggccaa gacttaattt tgaatgacat tgggactatt gccaaaaatc    720

aaatccatct tcatgttgtc cacttctcag ccttaattga atagggaaaa cctgctttct    780

gcaaacaact gaaaaagctg catttagaaa ctgtttcttt ggccctcatc gagaagctgg    840

aacttgtatt gttaggcccc ttatgggaca agctctcaac tgctgatcac ccagtgattg    900

tcaccatggc cagcaagagg aaatccacca caccatgcat gatcccagtg aagactgtgg    960

tgttgcaaga tgccagcatg gaggcccagc ccgctgagac cttgcctgaa ggaccccagc   1020

aggatctgcc cccagaagca tctgctgcca gcagtgaggc agcacagaac cccagcagta   1080

ctgatggctc tacactggcc aatgggcatc ggagcacttt agatggctat ttatattcct   1140

gtaaatactg cgatttcaga tcccatgaca tgacccaatt tgtgggacat atgaactcag   1200

agcacacaga ctttaataaa gacccaacct ttgtatgcag tgggtgcagt tttctggcaa   1260

aaacccctga ggggctttcc ttgcacaatg ccacatgtca ctccggggaa gccagctttg   1320

tgtggaacgt ggccaagcca gacaatcatg tggttgtgga gcagagcatc cctgagagca   1380

ccagcactcc tgacctagcg ggtgagccca gtgctgaagg ggctgatgga caggcagaaa   1440

tcatcattac caaaactcca atcatgaaga taatgaaagg caaagctgaa gccaaaaaaa   1500

ttcatacact caaggagaat gtccctagcc agcctgtggg tgaggcctta ccaaagctgt   1560

cgactggaga aatggaggtg agagaggggg accattcctt catcaatggg gcagttccag   1620

tcagccaggc atctgccagc tctgcaaaaa acccccatgc cgccaacggg cccctgatag   1680

gaacagtgcc agttttgcca gctggcatag cacagttcct ctccctccag cagcagcccc   1740

cagtgcatgc ccaacaccat gtccaccagc cactgcccac ggccaaggcc cttcccaaag   1800

tgatgatccc cctgagcagc attccaacgt acaatgcagc catggactct aacagcttcc   1860

tgaagaactc cttccacaag ttcccctacc ccaccaaagc cgagctctgc tatttgactg   1920

tggtgaccaa gtatccagaa gaacagctca agatctggtt cacagcccaa aggctgaagc   1980

aggggatcag ctggtcccct gaggagattg aggatgcccg gaaaaagatg ttcaatacag   2040

tcatccagtc tgtgcctcag cccacaatta cggttctaaa taccccactc gtcgccagtg   2100

ctggcaatgt ccagcatctc atccaggccg ctcttccagg tcacgttgtg gggcagccag   2160

agggtacagg agggggactt ctggtcactc agccattgat ggccaatggg ttgcaagcaa   2220

caagttcccc tctccccctc acggtgacat ccgtccccaa gcagccaggt gtggcaccca   2280

ttaacactgt gtgttcaaat acaacgtcag ctgtgaaggt ggtcaatgcg gcccagtcgc   2340

tcctcacggc ctgccccagc ataacctccc aagccttcct tgatgctagc atctacaaaa   2400

ataagaaatc tcatgaacag ctgtcagctc tgaaagggag cttctgtcgg aaccagttcc   2460

cagggcagag cgaagttgaa catctcacaa aagtgacggg cctcagtacc agagaggtgc   2520

ggaaatggtt cagtgatcgt agataccact gccggaactt gaagggctcc agagcgatga   2580

tacctggaga tcacagttcc atcatcattg actctgtgcc agaggtgtcc ttctccccat   2640

cgtccaaggt ccctgaggta acctgcattc cgacaacagc cacactagca acccaccctt   2700

ctgccaaacg acaatcttgg caccagactc ctgacttcac accaaccaaa tacaaggaga   2760

gagcccctga gcagctcaga gccctggaga gcagttttgc acaaaaccct cttcctcttg   2820

atgaggaact ggaccgcctg agaagtgaaa ccaaaatgac ccgacgagaa attgatagct   2880

ggttttcaga gagacggaaa aaagtgaatg ctgaggagac caagaaggct gaggagaatg   2940

cctctcagga ggaagaggag gctgctgagg atgagggtgg agaagaggat ttggccagtg   3000

agctaagggt ctctggtgaa aatggctctc tggaaatgcc cagcagccat atcttggcag   3060

agcgcaaagt cagccccatt aaaatcaacc tgaagaacct gagggtcact gaagccaatg   3120

gcaggaacga gattccaggg ctgggtgcct gtgaccctga ggatgatgag tcaaacaaac   3180

tggcagagca gctcccaggc aaagtgagct gcaaaaagac tgcccagcag cggcacttgc   3240

tgcggcagct ctttgtccag acacagtggc caagcaacca ggactatgac tccatcatgg   3300

cccagacggg tctgccacgg ccagaggtgg tgcgctggtt tggagatagc aggtacgcac   3360

tgaagaacgg ccaactcaaa tggtacgaag actataagcg aggcaacttc ccaccagggc   3420

tactggtcat tgcccctggc aaccgggagc tcctgcagga ctattacatg acacacaaga   3480

tgctgtatga agaggacctg cagaacctct gtgacaagac ccagatgagc tcccagcagg   3540

tcaagcagtg gtttgctgag aaaatggggg aggagaccag agccgtggca gacacaggca   3600

gtgaggacca gggccctggt actggtgagc tcacagcagt tcacaaaggg atgggtgaca   3660

cctattcaga ggtgtctgag aacagtgagt cgtgggagcc ccgtgtccct gaggccagct   3720

cagagccctt tgacacatcg agtccccagg ctggacgtca gctcgaaaca gactgaattt   3780

gatctgatta atgtgaagga ctggccagtc tgggaaaccg cctgccacgt ggaagagcca   3840

aacccgactc tctgctgcca catgccgttc ccatgcccgg ctgctgggca cctgggagag   3900

cttccagaat cctcgcagac agcccagagc ctgccgctac cctcggcctg cccaccacca   3960

agcaagcagc aagcaagatg gggttctcat cagttcttcc tcccacaatg taggaccttt   4020

cctttacctt ccaatggata aaatagttca gagttcatag tcatattcat agacacagaa   4080

tcaagctttt aacatataca tccacctcta tatgttaaat aaaacatcag attatcaaca   4140

ctgtc                                                               4145


<210>  10126
<211>  956
<212>  PRT
<213>  Homo sapiens

<400>  10126

Met Ala Ser Lys Arg Lys Ser Thr Thr Pro Cys Met Ile Pro Val Lys 
1               5                   10                  15


Thr Val Val Leu Gln Asp Ala Ser Met Glu Ala Gln Pro Ala Glu Thr 
            20                  25                  30


Leu Pro Glu Gly Pro Gln Gln Asp Leu Pro Pro Glu Ala Ser Ala Ala 
        35                  40                  45


Ser Ser Glu Ala Ala Gln Asn Pro Ser Ser Thr Asp Gly Ser Thr Leu 
    50                  55                  60


Ala Asn Gly His Arg Ser Thr Leu Asp Gly Tyr Leu Tyr Ser Cys Lys 
65                  70                  75                  80


Tyr Cys Asp Phe Arg Ser His Asp Met Thr Gln Phe Val Gly His Met 
                85                  90                  95


Asn Ser Glu His Thr Asp Phe Asn Lys Asp Pro Thr Phe Val Cys Ser 
            100                 105                 110


Gly Cys Ser Phe Leu Ala Lys Thr Pro Glu Gly Leu Ser Leu His Asn 
        115                 120                 125


Ala Thr Cys His Ser Gly Glu Ala Ser Phe Val Trp Asn Val Ala Lys 
    130                 135                 140


Pro Asp Asn His Val Val Val Glu Gln Ser Ile Pro Glu Ser Thr Ser 
145                 150                 155                 160


Thr Pro Asp Leu Ala Gly Glu Pro Ser Ala Glu Gly Ala Asp Gly Gln 
                165                 170                 175


Ala Glu Ile Ile Ile Thr Lys Thr Pro Ile Met Lys Ile Met Lys Gly 
            180                 185                 190


Lys Ala Glu Ala Lys Lys Ile His Thr Leu Lys Glu Asn Val Pro Ser 
        195                 200                 205


Gln Pro Val Gly Glu Ala Leu Pro Lys Leu Ser Thr Gly Glu Met Glu 
    210                 215                 220


Val Arg Glu Gly Asp His Ser Phe Ile Asn Gly Ala Val Pro Val Ser 
225                 230                 235                 240


Gln Ala Ser Ala Ser Ser Ala Lys Asn Pro His Ala Ala Asn Gly Pro 
                245                 250                 255


Leu Ile Gly Thr Val Pro Val Leu Pro Ala Gly Ile Ala Gln Phe Leu 
            260                 265                 270


Ser Leu Gln Gln Gln Pro Pro Val His Ala Gln His His Val His Gln 
        275                 280                 285


Pro Leu Pro Thr Ala Lys Ala Leu Pro Lys Val Met Ile Pro Leu Ser 
    290                 295                 300


Ser Ile Pro Thr Tyr Asn Ala Ala Met Asp Ser Asn Ser Phe Leu Lys 
305                 310                 315                 320


Asn Ser Phe His Lys Phe Pro Tyr Pro Thr Lys Ala Glu Leu Cys Tyr 
                325                 330                 335


Leu Thr Val Val Thr Lys Tyr Pro Glu Glu Gln Leu Lys Ile Trp Phe 
            340                 345                 350


Thr Ala Gln Arg Leu Lys Gln Gly Ile Ser Trp Ser Pro Glu Glu Ile 
        355                 360                 365


Glu Asp Ala Arg Lys Lys Met Phe Asn Thr Val Ile Gln Ser Val Pro 
    370                 375                 380


Gln Pro Thr Ile Thr Val Leu Asn Thr Pro Leu Val Ala Ser Ala Gly 
385                 390                 395                 400


Asn Val Gln His Leu Ile Gln Ala Ala Leu Pro Gly His Val Val Gly 
                405                 410                 415


Gln Pro Glu Gly Thr Gly Gly Gly Leu Leu Val Thr Gln Pro Leu Met 
            420                 425                 430


Ala Asn Gly Leu Gln Ala Thr Ser Ser Pro Leu Pro Leu Thr Val Thr 
        435                 440                 445


Ser Val Pro Lys Gln Pro Gly Val Ala Pro Ile Asn Thr Val Cys Ser 
    450                 455                 460


Asn Thr Thr Ser Ala Val Lys Val Val Asn Ala Ala Gln Ser Leu Leu 
465                 470                 475                 480


Thr Ala Cys Pro Ser Ile Thr Ser Gln Ala Phe Leu Asp Ala Ser Ile 
                485                 490                 495


Tyr Lys Asn Lys Lys Ser His Glu Gln Leu Ser Ala Leu Lys Gly Ser 
            500                 505                 510


Phe Cys Arg Asn Gln Phe Pro Gly Gln Ser Glu Val Glu His Leu Thr 
        515                 520                 525


Lys Val Thr Gly Leu Ser Thr Arg Glu Val Arg Lys Trp Phe Ser Asp 
    530                 535                 540


Arg Arg Tyr His Cys Arg Asn Leu Lys Gly Ser Arg Ala Met Ile Pro 
545                 550                 555                 560


Gly Asp His Ser Ser Ile Ile Ile Asp Ser Val Pro Glu Val Ser Phe 
                565                 570                 575


Ser Pro Ser Ser Lys Val Pro Glu Val Thr Cys Ile Pro Thr Thr Ala 
            580                 585                 590


Thr Leu Ala Thr His Pro Ser Ala Lys Arg Gln Ser Trp His Gln Thr 
        595                 600                 605


Pro Asp Phe Thr Pro Thr Lys Tyr Lys Glu Arg Ala Pro Glu Gln Leu 
    610                 615                 620


Arg Ala Leu Glu Ser Ser Phe Ala Gln Asn Pro Leu Pro Leu Asp Glu 
625                 630                 635                 640


Glu Leu Asp Arg Leu Arg Ser Glu Thr Lys Met Thr Arg Arg Glu Ile 
                645                 650                 655


Asp Ser Trp Phe Ser Glu Arg Arg Lys Lys Val Asn Ala Glu Glu Thr 
            660                 665                 670


Lys Lys Ala Glu Glu Asn Ala Ser Gln Glu Glu Glu Glu Ala Ala Glu 
        675                 680                 685


Asp Glu Gly Gly Glu Glu Asp Leu Ala Ser Glu Leu Arg Val Ser Gly 
    690                 695                 700


Glu Asn Gly Ser Leu Glu Met Pro Ser Ser His Ile Leu Ala Glu Arg 
705                 710                 715                 720


Lys Val Ser Pro Ile Lys Ile Asn Leu Lys Asn Leu Arg Val Thr Glu 
                725                 730                 735


Ala Asn Gly Arg Asn Glu Ile Pro Gly Leu Gly Ala Cys Asp Pro Glu 
            740                 745                 750


Asp Asp Glu Ser Asn Lys Leu Ala Glu Gln Leu Pro Gly Lys Val Ser 
        755                 760                 765


Cys Lys Lys Thr Ala Gln Gln Arg His Leu Leu Arg Gln Leu Phe Val 
    770                 775                 780


Gln Thr Gln Trp Pro Ser Asn Gln Asp Tyr Asp Ser Ile Met Ala Gln 
785                 790                 795                 800


Thr Gly Leu Pro Arg Pro Glu Val Val Arg Trp Phe Gly Asp Ser Arg 
                805                 810                 815


Tyr Ala Leu Lys Asn Gly Gln Leu Lys Trp Tyr Glu Asp Tyr Lys Arg 
            820                 825                 830


Gly Asn Phe Pro Pro Gly Leu Leu Val Ile Ala Pro Gly Asn Arg Glu 
        835                 840                 845


Leu Leu Gln Asp Tyr Tyr Met Thr His Lys Met Leu Tyr Glu Glu Asp 
    850                 855                 860


Leu Gln Asn Leu Cys Asp Lys Thr Gln Met Ser Ser Gln Gln Val Lys 
865                 870                 875                 880


Gln Trp Phe Ala Glu Lys Met Gly Glu Glu Thr Arg Ala Val Ala Asp 
                885                 890                 895


Thr Gly Ser Glu Asp Gln Gly Pro Gly Thr Gly Glu Leu Thr Ala Val 
            900                 905                 910


His Lys Gly Met Gly Asp Thr Tyr Ser Glu Val Ser Glu Asn Ser Glu 
        915                 920                 925


Ser Trp Glu Pro Arg Val Pro Glu Ala Ser Ser Glu Pro Phe Asp Thr 
    930                 935                 940


Ser Ser Pro Gln Ala Gly Arg Gln Leu Glu Thr Asp 
945                 950                 955


<210>  10127
<211>  3731
<212>  DNA
<213>  Homo sapiens

<400>  10127
gaaagatgag cttctgcctt tatatccttc tctcctgcta cccaactcat tgtggtgaag     60

gaaaaagaaa acgcgggtgg agactgcact atatgcttag gactgaaatg caactgcaga    120

agcaacatgt gaccttttag agatgcttgt gggactgcat aaagtgaaga gggaaactgg    180

aaaaaaacaa tgaacattta tcaccatcca gccactgtag ataaatttga ttggctgtct    240

ccctgccttc ccttcacacc cagtaccttc cctgcctgaa atcctcattg agggcaagaa    300

ctttatcccc aggatctaaa ccagtgctgg acaatagatg ctcaatgagg aaactgagac    360

acagcttaag aattttgccc aaagctacaa agattgaata gggaaaacct gctttctgca    420

aacaactgaa aaagctgcat ttagaaactg tttctttggc cctcatcgag aagctggaac    480

ttgtattgtt aggcccctta tgggacaagc tctcaactgc tgatcaccca gtgattgtca    540

ccatggccag caagaggaaa tccaccacac catgcatgat cccagtgaag actgtggtgt    600

tgcaagatgc cagcatggag gcccagcccg ctgagacctt gcctgaagga ccccagcagg    660

atctgccccc agaagcatct gctgccagca gtgaggcagc acagaacccc agcagtactg    720

atggctctac actggccaat gggcatcgga gcactttaga tggctattta tattcctgta    780

aatactgcga tttcagatcc catgacatga cccaatttgt gggacatatg aactcagagc    840

acacagactt taataaagac ccaacctttg tatgcagtgg gtgcagtttt ctggcaaaaa    900

cccctgaggg gctttccttg cacaatgcca catgtcactc cggggaagcc agctttgtgt    960

ggaacgtggc caagccagac aatcatgtgg ttgtggagca gagcatccct gagagcacca   1020

gcactcctga cctagcgggt gagcccagtg ctgaaggggc tgatggacag gcagaaatca   1080

tcattaccaa aactccaatc atgaagataa tgaaaggcaa agctgaagcc aaaaaaattc   1140

atacactcaa ggagaatgtc cctagccagc ctgtgggtga ggccttacca aagctgtcga   1200

ctggagaaat ggaggtgaga gagggggacc attccttcat caatggggca gttccagtca   1260

gccaggcatc tgccagctct gcaaaaaacc cccatgccgc caacgggccc ctgataggaa   1320

cagtgccagt tttgccagct ggcatagcac agttcctctc cctccagcag cagcccccag   1380

tgcatgccca acaccatgtc caccagccac tgcccacggc caaggccctt cccaaagtga   1440

tgatccccct gagcagcatt ccaacgtaca atgcagccat ggactctaac agcttcctga   1500

agaactcctt ccacaagttc ccctacccca ccaaagccga gctctgctat ttgactgtgg   1560

tgaccaagta tccagaagaa cagctcaaga tctggttcac agcccaaagg ctgaagcagg   1620

ggatcagctg gtcccctgag gagattgagg atgcccggaa aaagatgttc aatacagtca   1680

tccagtctgt gcctcagccc acaattacgg ttctaaatac cccactcgtc gccagtgctg   1740

gcaatgtcca gcatctcatc caggccgctc ttccaggtca cgttgtgggg cagccagagg   1800

gtacaggagg gggacttctg gtcactcagc cattgatggc caatgggttg caagcaacaa   1860

gttcccctct ccccctcacg gtgacatccg tccccaagca gccaggtgtg gcacccatta   1920

acactgtgtg ttcaaataca acgtcagctg tgaaggtggt caatgcggcc cagtcgctcc   1980

tcacggcctg ccccagcata acctcccaag ccttccttga tgctagcatc tacaaaaata   2040

agaaatctca tgaacagctg tcagctctga aagggagctt ctgtcggaac cagttcccag   2100

ggcagagcga agttgaacat ctcacaaaag tgacgggcct cagtaccaga gaggtgcgga   2160

aatggttcag tgatcgtaga taccactgcc ggaacttgaa gggctccaga gcgatgatac   2220

ctggagatca cagttccatc atcattgact ctgtgccaga ggtgtccttc tccccatcgt   2280

ccaaggtccc tgaggtaacc tgcattccga caacagccac actagcaacc cacccttctg   2340

ccaaacgaca atcttggcac cagactcctg acttcacacc aaccaaatac aaggagagag   2400

cccctgagca gctcagagcc ctggagagca gttttgcaca aaaccctctt cctcttgatg   2460

aggaactgga ccgcctgaga agtgaaacca aaatgacccg acgagaaatt gatagctggt   2520

tttcagagag acggaaaaaa gtgaatgctg aggagaccaa gaaggctgag gagaatgcct   2580

ctcaggagga agaggaggct gctgaggatg agggtggaga agaggatttg gccagtgagc   2640

taagggtctc tggtgaaaat ggctctctgg aaatgcccag cagccatatc ttggcagagc   2700

gcaaagtcag ccccattaaa atcaacctga agaacctgag ggtcactgaa gccaatggca   2760

ggaacgagat tccagggctg ggtgcctgtg accctgagga tgatgagtca aacaaactgg   2820

cagagcagct cccaggcaaa gtgagctgca aaaagactgc ccagcagcgg cacttgctgc   2880

ggcagctctt tgtccagaca cagtggccaa gcaaccagga ctatgactcc atcatggccc   2940

agacgggtct gccacggcca gaggtggtgc gctggtttgg agatagcagg tacgcactga   3000

agaacggcca actcaaatgg tacgaagact ataagcgagg caacttccca ccagggctac   3060

tggtcattgc ccctggcaac cgggagctcc tgcaggacta ttacatgaca cacaagatgc   3120

tgtatgaaga ggacctgcag aacctctgtg acaagaccca gatgagctcc cagcaggtca   3180

agcagtggtt tgctgagaaa atgggggagg agaccagagc cgtggcagac acaggcagtg   3240

aggaccaggg ccctggtact ggtgagctca cagcagttca caaagggatg ggtgacacct   3300

attcagaggt gtctgagaac agtgagtcgt gggagccccg tgtccctgag gccagctcag   3360

agccctttga cacatcgagt ccccaggctg gacgtcagct cggtaaggag tccacagggg   3420

ccatggctat cctgtgtggg taaggggagg aggcacttat ggttgggcac tgaatttact   3480

gcacaggggc atctgctgtc tctaaggctg cctggcagca gcattaaccg cctggctgct   3540

tcagaggaca actagcagca gaagccatag gaatataata tgataaacgg ttgagagctg   3600

ttttttgttt catgtgtttt taaaaacctg cgcaggggaa ggaacatggt gaccctaaag   3660

gggtccaagc ttttctagcc atttcttagc aataggagaa caggtcaaaa catcctctga   3720

gtcgggcaga t                                                        3731


<210>  10128
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10128

Met Ser Phe Cys Leu Tyr Ile Leu Leu Ser Cys Tyr Pro Thr His Cys 
1               5                   10                  15


Gly Glu Gly Lys Arg Lys Arg Gly Trp Arg Leu His Tyr Met Leu Arg 
            20                  25                  30


Thr Glu Met Gln Leu Gln Lys Gln His Val Thr Phe 
        35                  40


<210>  10129
<211>  3537
<212>  DNA
<213>  Homo sapiens

<400>  10129
gaatgaaaga tgagcttctg cctttatatc cttctctcct gctacccaac tcattgtggt     60

gaaggaaaaa gaaaacgcgg gtggagactg cactatatgc ttaggactga aatgcaactg    120

cagaagcaac atgtgacctt ttagagatgc ttgtgggact gcataaagtg aagagggaaa    180

ctggaaaaaa acaatgaaat tgaataggga aaacctgctt tctgcaaaca actgaaaaag    240

ctgcatttag aaactgtttc tttggccctc atcgagaagc tggaacttgt attgttaggc    300

cccttatggg acaagctctc aactgctgat cacccagtga ttgtcaccat ggccagcaag    360

aggaaatcca ccacaccatg catgatccca gtgaagactg tggtgttgca agatgccagc    420

atggaggccc agcccgctga gaccttgcct gaaggacccc agcaggatct gcccccagaa    480

gcatctgctg ccagcagtga ggcagcacag aaccccagca gtactgatgg ctctacactg    540

gccaatgggc atcggagcac tttagatggc tatttatatt cctgtaaata ctgcgatttc    600

agatcccatg acatgaccca atttgtggga catatgaact cagagcacac agactttaat    660

aaagacccaa cctttgtatg cagtgggtgc agttttctgg caaaaacccc tgaggggctt    720

tccttgcaca atgccacatg tcactccggg gaagccagct ttgtgtggaa cgtggccaag    780

ccagacaatc atgtggttgt ggagcagagc atccctgaga gcaccagcac tcctgaccta    840

gcgggtgagc ccagtgctga aggggctgat ggacaggcag aaatcatcat taccaaaact    900

ccaatcatga agataatgaa aggcaaagct gaagccaaaa aaattcatac actcaaggag    960

aatgtcccta gccagcctgt gggtgaggcc ttaccaaagc tgtcgactgg agaaatggag   1020

gtgagagagg gggaccattc cttcatcaat ggggcagttc cagtcagcca ggcatctgcc   1080

agctctgcaa aaaaccccca tgccgccaac gggcccctga taggaacagt gccagttttg   1140

ccagctggca tagcacagtt cctctccctc cagcagcagc ccccagtgca tgcccaacac   1200

catgtccacc agccactgcc cacggccaag gcccttccca aagtgatgat ccccctgagc   1260

agcattccaa cgtacaatgc agccatggac tctaacagct tcctgaagaa ctccttccac   1320

aagttcccct accccaccaa agccgagctc tgctatttga ctgtggtgac caagtatcca   1380

gaagaacagc tcaagatctg gttcacagcc caaaggctga agcaggggat cagctggtcc   1440

cctgaggaga ttgaggatgc ccggaaaaag atgttcaata cagtcatcca gtctgtgcct   1500

cagcccacaa ttacggttct aaatacccca ctcgtcgcca gtgctggcaa tgtccagcat   1560

ctcatccagg ccgctcttcc aggtcacgtt gtggggcagc cagagggtac aggaggggga   1620

cttctggtca ctcagccatt gatggccaat gggttgcaag caacaagttc ccctctcccc   1680

ctcacggtga catccgtccc caagcagcca ggtgtggcac ccattaacac tgtgtgttca   1740

aatacaacgt cagctgtgaa ggtggtcaat gcggcccagt cgctcctcac ggcctgcccc   1800

agcataacct cccaagcctt ccttgatgct agcatctaca aaaataagaa atctcatgaa   1860

cagctgtcag ctctgaaagg gagcttctgt cggaaccagt tcccagggca gagcgaagtt   1920

gaacatctca caaaagtgac gggcctcagt accagagagg tgcggaaatg gttcagtgat   1980

cgtagatacc actgccggaa cttgaagggc tccagagcga tgatacctgg agatcacagt   2040

tccatcatca ttgactctgt gccagaggtg tccttctccc catcgtccaa ggtccctgag   2100

gtaacctgca ttccgacaac agccacacta gcaacccacc cttctgccaa acgacaatct   2160

tggcaccaga ctcctgactt cacaccaacc aaatacaagg agagagcccc tgagcagctc   2220

agagccctgg agagcagttt tgcacaaaac cctcttcctc ttgatgagga actggaccgc   2280

ctgagaagtg aaaccaaaat gacccgacga gaaattgata gctggttttc agagagacgg   2340

aaaaaagtga atgctgagga gaccaagaag gctgaggaga atgcctctca ggaggaagag   2400

gaggctgctg aggatgaggg tggagaagag gatttggcca gtgagctaag ggtctctggt   2460

gaaaatggct ctctggaaat gcccagcagc catatcttgg cagagcgcaa agtcagcccc   2520

attaaaatca acctgaagaa cctgagggtc actgaagcca atggcaggaa cgagattcca   2580

gggctgggtg cctgtgaccc tgaggatgat gagtcaaaca aactggcaga gcagctccca   2640

ggcaaagtga gctgcaaaaa gactgcccag cagcggcact tgctgcggca gctctttgtc   2700

cagacacagt ggccaagcaa ccaggactat gactccatca tggcccagac gggtctgcca   2760

cggccagagg tggtgcgctg gtttggagat agcaggtacg cactgaagaa cggccaactc   2820

aaatggtacg aagactataa gcgaggcaac ttcccaccag ggctactggt cattgcccct   2880

ggcaaccggg agctcctgca ggactattac atgacacaca agatgctgta tgaagaggac   2940

ctgcagaacc tctgtgacaa gacccagatg agctcccagc aggtcaagca gtggtttgct   3000

gagaaaatgg gggaggagac cagagccgtg gcagacacag gcagtgagga ccagggccct   3060

ggtactggtg agctcacagc agttcacaaa gggatgggtg acacctattc agaggtgtct   3120

gagaacagtg agtcgtggga gccccgtgtc cctgaggcca gctcagagcc ctttgacaca   3180

tcgagtcccc aggctggacg tcagctcggt aaggagtcca caggggccat ggctatcctg   3240

tgtgggtaag gggaggaggc acttatggtt gggcactgaa tttactgcac aggggcatct   3300

gctgtctcta aggctgcctg gcagcagcat taaccgcctg gctgcttcag aggacaacta   3360

gcagcagaag ccataggaat ataatatgat aaacggttga gagctgtttt ttgtttcatg   3420

tgtttttaaa aacctgcgca ggggaaggaa catggtgacc ctaaaggggt ccaagctttt   3480

ctagccattt cttagcaata ggagaacagg tcaaaacatc ctctgagtcg ggcagat      3537


<210>  10130
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10130

Met Ser Phe Cys Leu Tyr Ile Leu Leu Ser Cys Tyr Pro Thr His Cys 
1               5                   10                  15


Gly Glu Gly Lys Arg Lys Arg Gly Trp Arg Leu His Tyr Met Leu Arg 
            20                  25                  30


Thr Glu Met Gln Leu Gln Lys Gln His Val Thr Phe 
        35                  40


<210>  10131
<211>  3760
<212>  DNA
<213>  Homo sapiens

<400>  10131
aaatagactg aatgaaagat gagcttctgc ctttatatcc ttctctcctg ctacccaact     60

cattgtggtg aaggaaaaag aaaacgcggg tggagactgc actatatgct taggactgaa    120

atgcaactgc agaagcaaca tgtgaccttt tagagatgct tgtgggactg cataaagtga    180

agagggaaac tggaaaaaaa caatgaaatg aggaaactga gacacagctt aagaattttg    240

cccaaagcta caaaggctaa tcccgaactc ctggcctcaa atgatcttcc taccttggct    300

tcccaaagtg ctgggattac agacgtgagc tgctgtgcct ggccaagact taattttgaa    360

tgacattggg actattgcca aaaatcaaat ccatcttcat gttgtccact tctcagcctt    420

aattgaatag ggaaaacctg ctttctgcaa acaactgaaa aagctgcatt tagaaactgt    480

ttctttggcc ctcatcgaga agctggaact tgtattgtta ggccccttat gggacaagct    540

ctcaactgct gatcacccag tgattgtcac catggccagc aagaggaaat ccaccacacc    600

atgcatgatc ccagtgaaga ctgtggtgtt gcaagatgcc agcatggagg cccagcccgc    660

tgagaccttg cctgaaggac cccagcagga tctgccccca gaagcatctg ctgccagcag    720

tgaggcagca cagaacccca gcagtactga tggctctaca ctggccaatg ggcatcggag    780

cactttagat ggctatttat attcctgtaa atactgcgat ttcagatccc atgacatgac    840

ccaatttgtg ggacatatga actcagagca cacagacttt aataaagacc caacctttgt    900

atgcagtggg tgcagttttc tggcaaaaac ccctgagggg ctttccttgc acaatgccac    960

atgtcactcc ggggaagcca gctttgtgtg gaacgtggcc aagccagaca atcatgtggt   1020

tgtggagcag agcatccctg agagcaccag cactcctgac ctagcgggtg agcccagtgc   1080

tgaaggggct gatggacagg cagaaatcat cattaccaaa actccaatca tgaagataat   1140

gaaaggcaaa gctgaagcca aaaaaattca tacactcaag gagaatgtcc ctagccagcc   1200

tgtgggtgag gccttaccaa agctgtcgac tggagaaatg gaggtgagag agggggacca   1260

ttccttcatc aatggggcag ttccagtcag ccaggcatct gccagctctg caaaaaaccc   1320

ccatgccgcc aacgggcccc tgataggaac agtgccagtt ttgccagctg gcatagcaca   1380

gttcctctcc ctccagcagc agcccccagt gcatgcccaa caccatgtcc accagccact   1440

gcccacggcc aaggcccttc ccaaagtgat gatccccctg agcagcattc caacgtacaa   1500

tgcagccatg gactctaaca gcttcctgaa gaactccttc cacaagttcc cctaccccac   1560

caaagccgag ctctgctatt tgactgtggt gaccaagtat ccagaagaac agctcaagat   1620

ctggttcaca gcccaaaggc tgaagcaggg gatcagctgg tcccctgagg agattgagga   1680

tgcccggaaa aagatgttca atacagtcat ccagtctgtg cctcagccca caattacggt   1740

tctaaatacc ccactcgtcg ccagtgctgg caatgtccag catctcatcc aggccgctct   1800

tccaggtcac gttgtggggc agccagaggg tacaggaggg ggacttctgg tcactcagcc   1860

attgatggcc aatgggttgc aagcaacaag ttcccctctc cccctcacgg tgacatccgt   1920

ccccaagcag ccaggtgtgg cacccattaa cactgtgtgt tcaaatacaa cgtcagctgt   1980

gaaggtggtc aatgcggccc agtcgctcct cacggcctgc cccagcataa cctcccaagc   2040

cttccttgat gctagcatct acaaaaataa gaaatctcat gaacagctgt cagctctgaa   2100

agggagcttc tgtcggaacc agttcccagg gcagagcgaa gttgaacatc tcacaaaagt   2160

gacgggcctc agtaccagag aggtgcggaa atggttcagt gatcgtagat accactgccg   2220

gaacttgaag ggctccagag cgatgatacc tggagatcac agttccatca tcattgactc   2280

tgtgccagag gtgtccttct ccccatcgtc caaggtccct gaggtaacct gcattccgac   2340

aacagccaca ctagcaaccc acccttctgc caaacgacaa tcttggcacc agactcctga   2400

cttcacacca accaaataca aggagagagc ccctgagcag ctcagagccc tggagagcag   2460

ttttgcacaa aaccctcttc ctcttgatga ggaactggac cgcctgagaa gtgaaaccaa   2520

aatgacccga cgagaaattg atagctggtt ttcagagaga cggaaaaaag tgaatgctga   2580

ggagaccaag aaggctgagg agaatgcctc tcaggaggaa gaggaggctg ctgaggatga   2640

gggtggagaa gaggatttgg ccagtgagct aagggtctct ggtgaaaatg gctctctgga   2700

aatgcccagc agccatatct tggcagagcg caaagtcagc cccattaaaa tcaacctgaa   2760

gaacctgagg gtcactgaag ccaatggcag gaacgagatt ccagggctgg gtgcctgtga   2820

ccctgaggat gatgagtcaa acaaactggc agagcagctc ccaggcaaag tgagctgcaa   2880

aaagactgcc cagcagcggc acttgctgcg gcagctcttt gtccagacac agtggccaag   2940

caaccaggac tatgactcca tcatggccca gacgggtctg ccacggccag aggtggtgcg   3000

ctggtttgga gatagcaggt acgcactgaa gaacggccaa ctcaaatggt acgaagacta   3060

taagcgaggc aacttcccac cagggctact ggtcattgcc cctggcaacc gggagctcct   3120

gcaggactat tacatgacac acaagatgct gtatgaagag gacctgcaga acctctgtga   3180

caagacccag atgagctccc agcaggtcaa gcagtggttt gctgagaaaa tgggggagga   3240

gaccagagcc gtggcagaca caggcagtga ggaccagggc cctggtactg gtgagctcac   3300

agcagttcac aaagggatgg gtgacaccta ttcagaggtg tctgagaaca gtgagtcgtg   3360

ggagccccgt gtccctgagg ccagctcaga gccctttgac acatcgagtc cccaggctgg   3420

acgtcagctc ggtaaggagt ccacaggggc catggctatc ctgtgtgggt aaggggagga   3480

ggcacttatg gttgggcact gaatttactg cacaggggca tctgctgtct ctaaggctgc   3540

ctggcagcag cattaaccgc ctggctgctt cagaggacaa ctagcagcag aagccatagg   3600

aatataatat gataaacggt tgagagctgt tttttgtttc atgtgttttt aaaaacctgc   3660

gcaggggaag gaacatggtg accctaaagg ggtccaagct tttctagcca tttcttagca   3720

ataggagaac aggtcaaaac atcctctgag tcgggcagat                         3760


<210>  10132
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  10132

Met Arg Lys Leu Arg His Ser Leu Arg Ile Leu Pro Lys Ala Thr Lys 
1               5                   10                  15


Ala Asn Pro Glu Leu Leu Ala Ser Asn Asp Leu Pro Thr Leu Ala Ser 
            20                  25                  30


Gln Ser Ala Gly Ile Thr Asp Val Ser Cys Cys Ala Trp Pro Arg Leu 
        35                  40                  45


Asn Phe Glu 
    50


<210>  10133
<211>  3594
<212>  DNA
<213>  Homo sapiens

<400>  10133
aaatagactg aatgaaagat gagcttctgc ctttatatcc ttctctcctg ctacccaact     60

cattgtggtg aaggaaaaag aaaacgcggg tggagactgc actatatgct taggactgaa    120

atgcaactgc agaagcaaca tgtgaccttt tagagatgct tgtgggactg cataaagtga    180

agagggaaac tggaaaaaaa caatgaaatg aggaaactga gacacagctt aagaattttg    240

cccaaagcta caaagattga atagggaaaa cctgctttct gcaaacaact gaaaaagctg    300

catttagaaa ctgtttcttt ggccctcatc gagaagctgg aacttgtatt gttaggcccc    360

ttatgggaca agctctcaac tgctgatcac ccagtgattg tcaccatggc cagcaagagg    420

aaatccacca caccatgcat gatcccagtg aagactgtgg tgttgcaaga tgccagcatg    480

gaggcccagc ccgctgagac cttgcctgaa ggaccccagc aggatctgcc cccagaagca    540

tctgctgcca gcagtgaggc agcacagaac cccagcagta ctgatggctc tacactggcc    600

aatgggcatc ggagcacttt agatggctat ttatattcct gtaaatactg cgatttcaga    660

tcccatgaca tgacccaatt tgtgggacat atgaactcag agcacacaga ctttaataaa    720

gacccaacct ttgtatgcag tgggtgcagt tttctggcaa aaacccctga ggggctttcc    780

ttgcacaatg ccacatgtca ctccggggaa gccagctttg tgtggaacgt ggccaagcca    840

gacaatcatg tggttgtgga gcagagcatc cctgagagca ccagcactcc tgacctagcg    900

ggtgagccca gtgctgaagg ggctgatgga caggcagaaa tcatcattac caaaactcca    960

atcatgaaga taatgaaagg caaagctgaa gccaaaaaaa ttcatacact caaggagaat   1020

gtccctagcc agcctgtggg tgaggcctta ccaaagctgt cgactggaga aatggaggtg   1080

agagaggggg accattcctt catcaatggg gcagttccag tcagccaggc atctgccagc   1140

tctgcaaaaa acccccatgc cgccaacggg cccctgatag gaacagtgcc agttttgcca   1200

gctggcatag cacagttcct ctccctccag cagcagcccc cagtgcatgc ccaacaccat   1260

gtccaccagc cactgcccac ggccaaggcc cttcccaaag tgatgatccc cctgagcagc   1320

attccaacgt acaatgcagc catggactct aacagcttcc tgaagaactc cttccacaag   1380

ttcccctacc ccaccaaagc cgagctctgc tatttgactg tggtgaccaa gtatccagaa   1440

gaacagctca agatctggtt cacagcccaa aggctgaagc aggggatcag ctggtcccct   1500

gaggagattg aggatgcccg gaaaaagatg ttcaatacag tcatccagtc tgtgcctcag   1560

cccacaatta cggttctaaa taccccactc gtcgccagtg ctggcaatgt ccagcatctc   1620

atccaggccg ctcttccagg tcacgttgtg gggcagccag agggtacagg agggggactt   1680

ctggtcactc agccattgat ggccaatggg ttgcaagcaa caagttcccc tctccccctc   1740

acggtgacat ccgtccccaa gcagccaggt gtggcaccca ttaacactgt gtgttcaaat   1800

acaacgtcag ctgtgaaggt ggtcaatgcg gcccagtcgc tcctcacggc ctgccccagc   1860

ataacctccc aagccttcct tgatgctagc atctacaaaa ataagaaatc tcatgaacag   1920

ctgtcagctc tgaaagggag cttctgtcgg aaccagttcc cagggcagag cgaagttgaa   1980

catctcacaa aagtgacggg cctcagtacc agagaggtgc ggaaatggtt cagtgatcgt   2040

agataccact gccggaactt gaagggctcc agagcgatga tacctggaga tcacagttcc   2100

atcatcattg actctgtgcc agaggtgtcc ttctccccat cgtccaaggt ccctgaggta   2160

acctgcattc cgacaacagc cacactagca acccaccctt ctgccaaacg acaatcttgg   2220

caccagactc ctgacttcac accaaccaaa tacaaggaga gagcccctga gcagctcaga   2280

gccctggaga gcagttttgc acaaaaccct cttcctcttg atgaggaact ggaccgcctg   2340

agaagtgaaa ccaaaatgac ccgacgagaa attgatagct ggttttcaga gagacggaaa   2400

aaagtgaatg ctgaggagac caagaaggct gaggagaatg cctctcagga ggaagaggag   2460

gctgctgagg atgagggtgg agaagaggat ttggccagtg agctaagggt ctctggtgaa   2520

aatggctctc tggaaatgcc cagcagccat atcttggcag agcgcaaagt cagccccatt   2580

aaaatcaacc tgaagaacct gagggtcact gaagccaatg gcaggaacga gattccaggg   2640

ctgggtgcct gtgaccctga ggatgatgag tcaaacaaac tggcagagca gctcccaggc   2700

aaagtgagct gcaaaaagac tgcccagcag cggcacttgc tgcggcagct ctttgtccag   2760

acacagtggc caagcaacca ggactatgac tccatcatgg cccagacggg tctgccacgg   2820

ccagaggtgg tgcgctggtt tggagatagc aggtacgcac tgaagaacgg ccaactcaaa   2880

tggtacgaag actataagcg aggcaacttc ccaccagggc tactggtcat tgcccctggc   2940

aaccgggagc tcctgcagga ctattacatg acacacaaga tgctgtatga agaggacctg   3000

cagaacctct gtgacaagac ccagatgagc tcccagcagg tcaagcagtg gtttgctgag   3060

aaaatggggg aggagaccag agccgtggca gacacaggca gtgaggacca gggccctggt   3120

actggtgagc tcacagcagt tcacaaaggg atgggtgaca cctattcaga ggtgtctgag   3180

aacagtgagt cgtgggagcc ccgtgtccct gaggccagct cagagccctt tgacacatcg   3240

agtccccagg ctggacgtca gctcggtaag gagtccacag gggccatggc tatcctgtgt   3300

gggtaagggg aggaggcact tatggttggg cactgaattt actgcacagg ggcatctgct   3360

gtctctaagg ctgcctggca gcagcattaa ccgcctggct gcttcagagg acaactagca   3420

gcagaagcca taggaatata atatgataaa cggttgagag ctgttttttg tttcatgtgt   3480

ttttaaaaac ctgcgcaggg gaaggaacat ggtgacccta aaggggtcca agcttttcta   3540

gccatttctt agcaatagga gaacaggtca aaacatcctc tgagtcgggc agat         3594


<210>  10134
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10134

Met Ser Phe Cys Leu Tyr Ile Leu Leu Ser Cys Tyr Pro Thr His Cys 
1               5                   10                  15


Gly Glu Gly Lys Arg Lys Arg Gly Trp Arg Leu His Tyr Met Leu Arg 
            20                  25                  30


Thr Glu Met Gln Leu Gln Lys Gln His Val Thr Phe 
        35                  40


<210>  10135
<211>  3893
<212>  DNA
<213>  Homo sapiens

<400>  10135
gtgctgaatt gtgatagccg tcaaaggcag caaatagact gaatgaaaga tgagcttctg     60

cctttatatc cttctctcct gctacccaac tcattgtggt gaaggaaaaa gaaaacgcgg    120

gtggagactg cactatatgc ttaggactga aatgcaactg cagaagcaac atgtgacctt    180

ttagagatgc ttgtgggact gcataaagtg aagagggaaa ctggaaaaaa acaatgaaca    240

tttatcacca tccagccact gtagataaat ttgattggct gtctccctgc cttcccttca    300

cacccagtac cttccctgcc tgaaatcctc attgagggca agaactttat ccccaggatc    360

taaaccagtg ctggacaata gatgctcagc taatcccgaa ctcctggcct caaatgatct    420

tcctaccttg gcttcccaaa gtgctgggat tacagacgtg agctgctgtg cctggccaag    480

acttaatttt gaatgacatt gggactattg ccaaaaatca aatccatctt catgttgtcc    540

acttctcagc cttaattgaa tagggaaaac ctgctttctg caaacaactg aaaaagctgc    600

atttagaaac tgtttctttg gccctcatcg agaagctgga acttgtattg ttaggcccct    660

tatgggacaa gctctcaact gctgatcacc cagtgattgt caccatggcc agcaagagga    720

aatccaccac accatgcatg atcccagtga agactgtggt gttgcaagat gccagcatgg    780

aggcccagcc cgctgagacc ttgcctgaag gaccccagca ggatctgccc ccagaagcat    840

ctgctgccag cagtgaggca gcacagaacc ccagcagtac tgatggctct acactggcca    900

atgggcatcg gagcacttta gatggctatt tatattcctg taaatactgc gatttcagat    960

cccatgacat gacccaattt gtgggacata tgaactcaga gcacacagac tttaataaag   1020

acccaacctt tgtatgcagt gggtgcagtt ttctggcaaa aacccctgag gggctttcct   1080

tgcacaatgc cacatgtcac tccggggaag ccagctttgt gtggaacgtg gccaagccag   1140

acaatcatgt ggttgtggag cagagcatcc ctgagagcac cagcactcct gacctagcgg   1200

gtgagcccag tgctgaaggg gctgatggac aggcagaaat catcattacc aaaactccaa   1260

tcatgaagat aatgaaaggc aaagctgaag ccaaaaaaat tcatacactc aaggagaatg   1320

tccctagcca gcctgtgggt gaggccttac caaagctgtc gactggagaa atggaggtga   1380

gagaggggga ccattccttc atcaatgggg cagttccagt cagccaggca tctgccagct   1440

ctgcaaaaaa cccccatgcc gccaacgggc ccctgatagg aacagtgcca gttttgccag   1500

ctggcatagc acagttcctc tccctccagc agcagccccc agtgcatgcc caacaccatg   1560

tccaccagcc actgcccacg gccaaggccc ttcccaaagt gatgatcccc ctgagcagca   1620

ttccaacgta caatgcagcc atggactcta acagcttcct gaagaactcc ttccacaagt   1680

tcccctaccc caccaaagcc gagctctgct atttgactgt ggtgaccaag tatccagaag   1740

aacagctcaa gatctggttc acagcccaaa ggctgaagca ggggatcagc tggtcccctg   1800

aggagattga ggatgcccgg aaaaagatgt tcaatacagt catccagtct gtgcctcagc   1860

ccacaattac ggttctaaat accccactcg tcgccagtgc tggcaatgtc cagcatctca   1920

tccaggccgc tcttccaggt cacgttgtgg ggcagccaga gggtacagga gggggacttc   1980

tggtcactca gccattgatg gccaatgggt tgcaagcaac aagttcccct ctccccctca   2040

cggtgacatc cgtccccaag cagccaggtg tggcacccat taacactgtg tgttcaaata   2100

caacgtcagc tgtgaaggtg gtcaatgcgg cccagtcgct cctcacggcc tgccccagca   2160

taacctccca agccttcctt gatgctagca tctacaaaaa taagaaatct catgaacagc   2220

tgtcagctct gaaagggagc ttctgtcgga accagttccc agggcagagc gaagttgaac   2280

atctcacaaa agtgacgggc ctcagtacca gagaggtgcg gaaatggttc agtgatcgta   2340

gataccactg ccggaacttg aagggctcca gagcgatgat acctggagat cacagttcca   2400

tcatcattga ctctgtgcca gaggtgtcct tctccccatc gtccaaggtc cctgaggtaa   2460

cctgcattcc gacaacagcc acactagcaa cccacccttc tgccaaacga caatcttggc   2520

accagactcc tgacttcaca ccaaccaaat acaaggagag agcccctgag cagctcagag   2580

ccctggagag cagttttgca caaaaccctc ttcctcttga tgaggaactg gaccgcctga   2640

gaagtgaaac caaaatgacc cgacgagaaa ttgatagctg gttttcagag agacggaaaa   2700

aagtgaatgc tgaggagacc aagaaggctg aggagaatgc ctctcaggag gaagaggagg   2760

ctgctgagga tgagggtgga gaagaggatt tggccagtga gctaagggtc tctggtgaaa   2820

atggctctct ggaaatgccc agcagccata tcttggcaga gcgcaaagtc agccccatta   2880

aaatcaacct gaagaacctg agggtcactg aagccaatgg caggaacgag attccagggc   2940

tgggtgcctg tgaccctgag gatgatgagt caaacaaact ggcagagcag ctcccaggca   3000

aagtgagctg caaaaagact gcccagcagc ggcacttgct gcggcagctc tttgtccaga   3060

cacagtggcc aagcaaccag gactatgact ccatcatggc ccagacgggt ctgccacggc   3120

cagaggtggt gcgctggttt ggagatagca ggtacgcact gaagaacggc caactcaaat   3180

ggtacgaaga ctataagcga ggcaacttcc caccagggct actggtcatt gcccctggca   3240

accgggagct cctgcaggac tattacatga cacacaagat gctgtatgaa gaggacctgc   3300

agaacctctg tgacaagacc cagatgagct cccagcaggt caagcagtgg tttgctgaga   3360

aaatggggga ggagaccaga gccgtggcag acacaggcag tgaggaccag ggccctggta   3420

ctggtgagct cacagcagtt cacaaaggga tgggtgacac ctattcagag gtgtctgaga   3480

acagtgagtc gtgggagccc cgtgtccctg aggccagctc agagcccttt gacacatcga   3540

gtccccaggc tggacgtcag ctcggtaagg agtccacagg ggccatggct atcctgtgtg   3600

ggtaagggga ggaggcactt atggttgggc actgaattta ctgcacaggg gcatctgctg   3660

tctctaaggc tgcctggcag cagcattaac cgcctggctg cttcagagga caactagcag   3720

cagaagccat aggaatataa tatgataaac ggttgagagc tgttttttgt ttcatgtgtt   3780

tttaaaaacc tgcgcagggg aaggaacatg gtgaccctaa aggggtccaa gcttttctag   3840

ccatttctta gcaataggag aacaggtcaa aacatcctct gagtcgggca gat          3893


<210>  10136
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10136

Met Ser Phe Cys Leu Tyr Ile Leu Leu Ser Cys Tyr Pro Thr His Cys 
1               5                   10                  15


Gly Glu Gly Lys Arg Lys Arg Gly Trp Arg Leu His Tyr Met Leu Arg 
            20                  25                  30


Thr Glu Met Gln Leu Gln Lys Gln His Val Thr Phe 
        35                  40


<210>  10137
<211>  3849
<212>  DNA
<213>  Homo sapiens

<400>  10137
attcttgtgt gctgaattgt gatagccgtc aaaggcagca aatagactga atgaaagatg     60

agcttctgcc tttatatcct tctctcctgc tacccaactc attgtggtga aggaaaaaga    120

aaacgcgggt ggagactgca ctatatgctt aggactgaaa tgcaactgca gaagcaacat    180

gtgacctttt agagatgctt gtgggactgc ataaagtgaa gagggaaact ggaaaaaaac    240

aatgaaatga ggaaactgag acacagctta agaattttgc ccaaagctac aaagtccctt    300

ccataggaaa cagggaatgt ttgtttctgt cttctggtag gagaaggatt ggtcccaccc    360

ccagctccag ggatggatct tgattgttta agcccagtca gtgattctaa cccatggacc    420

aagaccctgc cttggagatt ggggaacagg tgttggaagg gctctatttt ggcaaagaat    480

ggattattta tgtgagcata tttccgcaaa attgaatagg gaaaacctgc tttctgcaaa    540

caactgaaaa agctgcattt agaaactgtt tctttggccc tcatcgagaa gctggaactt    600

gtattgttag gccccttatg ggacaagctc tcaactgctg atcacccagt gattgtcacc    660

atggccagca agaggaaatc caccacacca tgcatgatcc cagtgaagac tgtggtgttg    720

caagatgcca gcatggaggc ccagcccgct gagaccttgc ctgaaggacc ccagcaggat    780

ctgcccccag aagcatctgc tgccagcagt gaggcagcac agaaccccag cagtactgat    840

ggctctacac tggccaatgg gcatcggagc actttagatg gctatttata ttcctgtaaa    900

tactgcgatt tcagatccca tgacatgacc caatttgtgg gacatatgaa ctcagagcac    960

acagacttta ataaagaccc aacctttgta tgcagtgggt gcagttttct ggcaaaaacc   1020

cctgaggggc tttccttgca caatgccaca tgtcactccg gggaagccag ctttgtgtgg   1080

aacgtggcca agccagacaa tcatgtggtt gtggagcaga gcatccctga gagcaccagc   1140

actcctgacc tagcgggtga gcccagtgct gaaggggctg atggacaggc agaaatcatc   1200

attaccaaaa ctccaatcat gaagataatg aaaggcaaag ctgaagccaa aaaaattcat   1260

acactcaagg agaatgtccc tagccagcct gtgggtgagg ccttaccaaa gctgtcgact   1320

ggagaaatgg aggtgagaga gggggaccat tccttcatca atggggcagt tccagtcagc   1380

caggcatctg ccagctctgc aaaaaacccc catgccgcca acgggcccct gataggaaca   1440

gtgccagttt tgccagctgg catagcacag ttcctctccc tccagcagca gcccccagtg   1500

catgcccaac accatgtcca ccagccactg cccacggcca aggcccttcc caaagtgatg   1560

atccccctga gcagcattcc aacgtacaat gcagccatgg actctaacag cttcctgaag   1620

aactccttcc acaagttccc ctaccccacc aaagccgagc tctgctattt gactgtggtg   1680

accaagtatc cagaagaaca gctcaagatc tggttcacag cccaaaggct gaagcagggg   1740

atcagctggt cccctgagga gattgaggat gcccggaaaa agatgttcaa tacagtcatc   1800

cagtctgtgc ctcagcccac aattacggtt ctaaataccc cactcgtcgc cagtgctggc   1860

aatgtccagc atctcatcca ggccgctctt ccaggtcacg ttgtggggca gccagagggt   1920

acaggagggg gacttctggt cactcagcca ttgatggcca atgggttgca agcaacaagt   1980

tcccctctcc ccctcacggt gacatccgtc cccaagcagc caggtgtggc acccattaac   2040

actgtgtgtt caaatacaac gtcagctgtg aaggtggtca atgcggccca gtcgctcctc   2100

acggcctgcc ccagcataac ctcccaagcc ttccttgatg ctagcatcta caaaaataag   2160

aaatctcatg aacagctgtc agctctgaaa gggagcttct gtcggaacca gttcccaggg   2220

cagagcgaag ttgaacatct cacaaaagtg acgggcctca gtaccagaga ggtgcggaaa   2280

tggttcagtg atcgtagata ccactgccgg aacttgaagg gctccagagc gatgatacct   2340

ggagatcaca gttccatcat cattgactct gtgccagagg tgtccttctc cccatcgtcc   2400

aaggtccctg aggtaacctg cattccgaca acagccacac tagcaaccca cccttctgcc   2460

aaacgacaat cttggcacca gactcctgac ttcacaccaa ccaaatacaa ggagagagcc   2520

cctgagcagc tcagagccct ggagagcagt tttgcacaaa accctcttcc tcttgatgag   2580

gaactggacc gcctgagaag tgaaaccaaa atgacccgac gagaaattga tagctggttt   2640

tcagagagac ggaaaaaagt gaatgctgag gagaccaaga aggctgagga gaatgcctct   2700

caggaggaag aggaggctgc tgaggatgag ggtggagaag aggatttggc cagtgagcta   2760

agggtctctg gtgaaaatgg ctctctggaa atgcccagca gccatatctt ggcagagcgc   2820

aaagtcagcc ccattaaaat caacctgaag aacctgaggg tcactgaagc caatggcagg   2880

aacgagattc cagggctggg tgcctgtgac cctgaggatg atgagtcaaa caaactggca   2940

gagcagctcc caggcaaagt gagctgcaaa aagactgccc agcagcggca cttgctgcgg   3000

cagctctttg tccagacaca gtggccaagc aaccaggact atgactccat catggcccag   3060

acgggtctgc cacggccaga ggtggtgcgc tggtttggag atagcaggta cgcactgaag   3120

aacggccaac tcaaatggta cgaagactat aagcgaggca acttcccacc agggctactg   3180

gtcattgccc ctggcaaccg ggagctcctg caggactatt acatgacaca caagatgctg   3240

tatgaagagg acctgcagaa cctctgtgac aagacccaga tgagctccca gcaggtcaag   3300

cagtggtttg ctgagaaaat gggggaggag accagagccg tggcagacac aggcagtgag   3360

gaccagggcc ctggtactgg tgagctcaca gcagttcaca aagggatggg tgacacctat   3420

tcagaggtgt ctgagaacag tgagtcgtgg gagccccgtg tccctgaggc cagctcagag   3480

ccctttgaca catcgagtcc ccaggctgga cgtcagctcg gtaaggagtc cacaggggcc   3540

atggctatcc tgtgtgggta aggggaggag gcacttatgg ttgggcactg aatttactgc   3600

acaggggcat ctgctgtctc taaggctgcc tggcagcagc attaaccgcc tggctgcttc   3660

agaggacaac tagcagcaga agccatagga atataatatg ataaacggtt gagagctgtt   3720

ttttgtttca tgtgttttta aaaacctgcg caggggaagg aacatggtga ccctaaaggg   3780

gtccaagctt ttctagccat ttcttagcaa taggagaaca ggtcaaaaca tcctctgagt   3840

cgggcagat                                                           3849


<210>  10138
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10138

Met Ser Phe Cys Leu Tyr Ile Leu Leu Ser Cys Tyr Pro Thr His Cys 
1               5                   10                  15


Gly Glu Gly Lys Arg Lys Arg Gly Trp Arg Leu His Tyr Met Leu Arg 
            20                  25                  30


Thr Glu Met Gln Leu Gln Lys Gln His Val Thr Phe 
        35                  40


<210>  10139
<211>  3854
<212>  DNA
<213>  Homo sapiens

<400>  10139
gagcactaac attcttgtgt gctgaattgt gatagccgtc aaaggcagca aatagactga     60

atgaaagatg agcttctgcc tttatatcct tctctcctgc tacccaactc attgtggtga    120

aggaaaaaga aaacgcgggt ggagactgca ctatatgctt aggactgaaa tgcaactgca    180

gaagcaacat gtgacctttt agagatgctt gtgggactgc ataaagtgaa gagggaaact    240

ggaaaaaaac aatgaacatt tatcaccatc cagccactgt agataaattt gattggctgt    300

ctccctgcct tcccttcaca cccagtacct tccctgcctg aaatcctcat tgagggcaag    360

aactttatcc ccaggatcta aaccagtgct ggacaataga tgctcatgat tctaacccat    420

ggaccaagac cctgccttgg agattgggga acaggtgttg gaagggctct attttggcaa    480

agaatggatt atttatgtga gcatatttcc gcaaaattga atagggaaaa cctgctttct    540

gcaaacaact gaaaaagctg catttagaaa ctgtttcttt ggccctcatc gagaagctgg    600

aacttgtatt gttaggcccc ttatgggaca agctctcaac tgctgatcac ccagtgattg    660

tcaccatggc cagcaagagg aaatccacca caccatgcat gatcccagtg aagactgtgg    720

tgttgcaaga tgccagcatg gaggcccagc ccgctgagac cttgcctgaa ggaccccagc    780

aggatctgcc cccagaagca tctgctgcca gcagtgaggc agcacagaac cccagcagta    840

ctgatggctc tacactggcc aatgggcatc ggagcacttt agatggctat ttatattcct    900

gtaaatactg cgatttcaga tcccatgaca tgacccaatt tgtgggacat atgaactcag    960

agcacacaga ctttaataaa gacccaacct ttgtatgcag tgggtgcagt tttctggcaa   1020

aaacccctga ggggctttcc ttgcacaatg ccacatgtca ctccggggaa gccagctttg   1080

tgtggaacgt ggccaagcca gacaatcatg tggttgtgga gcagagcatc cctgagagca   1140

ccagcactcc tgacctagcg ggtgagccca gtgctgaagg ggctgatgga caggcagaaa   1200

tcatcattac caaaactcca atcatgaaga taatgaaagg caaagctgaa gccaaaaaaa   1260

ttcatacact caaggagaat gtccctagcc agcctgtggg tgaggcctta ccaaagctgt   1320

cgactggaga aatggaggtg agagaggggg accattcctt catcaatggg gcagttccag   1380

tcagccaggc atctgccagc tctgcaaaaa acccccatgc cgccaacggg cccctgatag   1440

gaacagtgcc agttttgcca gctggcatag cacagttcct ctccctccag cagcagcccc   1500

cagtgcatgc ccaacaccat gtccaccagc cactgcccac ggccaaggcc cttcccaaag   1560

tgatgatccc cctgagcagc attccaacgt acaatgcagc catggactct aacagcttcc   1620

tgaagaactc cttccacaag ttcccctacc ccaccaaagc cgagctctgc tatttgactg   1680

tggtgaccaa gtatccagaa gaacagctca agatctggtt cacagcccaa aggctgaagc   1740

aggggatcag ctggtcccct gaggagattg aggatgcccg gaaaaagatg ttcaatacag   1800

tcatccagtc tgtgcctcag cccacaatta cggttctaaa taccccactc gtcgccagtg   1860

ctggcaatgt ccagcatctc atccaggccg ctcttccagg tcacgttgtg gggcagccag   1920

agggtacagg agggggactt ctggtcactc agccattgat ggccaatggg ttgcaagcaa   1980

caagttcccc tctccccctc acggtgacat ccgtccccaa gcagccaggt gtggcaccca   2040

ttaacactgt gtgttcaaat acaacgtcag ctgtgaaggt ggtcaatgcg gcccagtcgc   2100

tcctcacggc ctgccccagc ataacctccc aagccttcct tgatgctagc atctacaaaa   2160

ataagaaatc tcatgaacag ctgtcagctc tgaaagggag cttctgtcgg aaccagttcc   2220

cagggcagag cgaagttgaa catctcacaa aagtgacggg cctcagtacc agagaggtgc   2280

ggaaatggtt cagtgatcgt agataccact gccggaactt gaagggctcc agagcgatga   2340

tacctggaga tcacagttcc atcatcattg actctgtgcc agaggtgtcc ttctccccat   2400

cgtccaaggt ccctgaggta acctgcattc cgacaacagc cacactagca acccaccctt   2460

ctgccaaacg acaatcttgg caccagactc ctgacttcac accaaccaaa tacaaggaga   2520

gagcccctga gcagctcaga gccctggaga gcagttttgc acaaaaccct cttcctcttg   2580

atgaggaact ggaccgcctg agaagtgaaa ccaaaatgac ccgacgagaa attgatagct   2640

ggttttcaga gagacggaaa aaagtgaatg ctgaggagac caagaaggct gaggagaatg   2700

cctctcagga ggaagaggag gctgctgagg atgagggtgg agaagaggat ttggccagtg   2760

agctaagggt ctctggtgaa aatggctctc tggaaatgcc cagcagccat atcttggcag   2820

agcgcaaagt cagccccatt aaaatcaacc tgaagaacct gagggtcact gaagccaatg   2880

gcaggaacga gattccaggg ctgggtgcct gtgaccctga ggatgatgag tcaaacaaac   2940

tggcagagca gctcccaggc aaagtgagct gcaaaaagac tgcccagcag cggcacttgc   3000

tgcggcagct ctttgtccag acacagtggc caagcaacca ggactatgac tccatcatgg   3060

cccagacggg tctgccacgg ccagaggtgg tgcgctggtt tggagatagc aggtacgcac   3120

tgaagaacgg ccaactcaaa tggtacgaag actataagcg aggcaacttc ccaccagggc   3180

tactggtcat tgcccctggc aaccgggagc tcctgcagga ctattacatg acacacaaga   3240

tgctgtatga agaggacctg cagaacctct gtgacaagac ccagatgagc tcccagcagg   3300

tcaagcagtg gtttgctgag aaaatggggg aggagaccag agccgtggca gacacaggca   3360

gtgaggacca gggccctggt actggtgagc tcacagcagt tcacaaaggg atgggtgaca   3420

cctattcaga ggtgtctgag aacagtgagt cgtgggagcc ccgtgtccct gaggccagct   3480

cagagccctt tgacacatcg agtccccagg ctggacgtca gctcggtaag gagtccacag   3540

gggccatggc tatcctgtgt gggtaagggg aggaggcact tatggttggg cactgaattt   3600

actgcacagg ggcatctgct gtctctaagg ctgcctggca gcagcattaa ccgcctggct   3660

gcttcagagg acaactagca gcagaagcca taggaatata atatgataaa cggttgagag   3720

ctgttttttg tttcatgtgt ttttaaaaac ctgcgcaggg gaaggaacat ggtgacccta   3780

aaggggtcca agcttttcta gccatttctt agcaatagga gaacaggtca aaacatcctc   3840

tgagtcgggc agat                                                     3854


<210>  10140
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  10140

Met Leu Met Ile Leu Thr His Gly Pro Arg Pro Cys Leu Gly Asp Trp 
1               5                   10                  15


Gly Thr Gly Val Gly Arg Ala Leu Phe Trp Gln Arg Met Asp Tyr Leu 
            20                  25                  30


Cys Glu His Ile Ser Ala Lys Leu Asn Arg Glu Asn Leu Leu Ser Ala 
        35                  40                  45


Asn Asn 
    50


<210>  10141
<211>  529
<212>  DNA
<213>  Homo sapiens

<400>  10141
agctctggac aggaaaacat gaaaacagat gatcccaagg aggtttctcc ctaaactaac     60

aattaaagaa tatagtttta ctttttcatt tttatttgtt gaaactggac tgaaatgcaa    120

ctgcagaagc aacatgtgac cttttagaga tgcttgtggg actgcataaa gtgaagaggg    180

aaactggaaa aaaacaatga acatttatca ccatccagcc actgtagata aatttgattg    240

gctgtctccc tgccttccct tcacacccag taccttccct gcctgaaatc ctcattgagg    300

gcaagaactt tatccccagg atctaaacca gtgctggaca atagatgctc atcccttcca    360

taggaaacag ggaatgtttg tttctgtctt ctggtaggag aaggattggt cccaccccca    420

gctccaggga tggatcttga ttgtttaagc ccagtcagtg attctaaccc atggaccaag    480

accctgcctt ggagattggg gaacaggtgt tggaagggct ctattttgg                529


<210>  10142
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  10142

Met Ile Pro Arg Arg Phe Leu Pro Lys Leu Thr Ile Lys Glu Tyr Ser 
1               5                   10                  15


Phe Thr Phe Ser Phe Leu Phe Val Glu Thr Gly Leu Lys Cys Asn Cys 
            20                  25                  30


Arg Ser Asn Met 
        35


<210>  10143
<211>  545
<212>  DNA
<213>  Homo sapiens

<400>  10143
gtgctttgta cattgggaag ttctttccag ctctggacag gaaaacatga aaacagatga     60

tcccaaggag gtttctccct aaactaacaa ttaaagaata tagttttact ttttcatttt    120

tatttgttga aactggtaaa gcttctacct tgagtgggtc tgggttgttt taaaatttat    180

cagaccacat tggtctgata ttgtttcctt catttaattt gaaaaagctt gtttaaaata    240

actatttgga gatggaataa ttttttggtt ttatgaaaat ttaaaggaat tgtaaaagaa    300

tctaagacat acttatggaa ttgcagtcaa gtttttctgg tgattttgac tgaaatgcaa    360

ctgcagaagc aacatgtgac cttttagaga tgcttgtggg actgcataaa gtgaagaggg    420

aaactggaaa aaaacaatga acatttatca ccatccagcc actgtagata aatttgattg    480

gctgtctccc tgccttccct tcacacccag taccttccct gcctgaaatc ctcattgagg    540

gcaag                                                                545


<210>  10144
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  10144

Met Ile Pro Arg Arg Phe Leu Pro Lys Leu Thr Ile Lys Glu Tyr Ser 
1               5                   10                  15


Phe Thr Phe Ser Phe Leu Phe Val Glu Thr Gly Lys Ala Ser Thr Leu 
            20                  25                  30


Ser Gly Ser Gly Leu Phe 
        35


<210>  10145
<211>  5414
<212>  DNA
<213>  Homo sapiens

<400>  10145
gtagaaggag tggagccgtg ctctcaccct gtcttagagg acccggaagc gccaagtgac     60

tgagggccga agacactcac ctgtggagcc tgtgcacgta ggtagaggcg gcggctctga    120

gtccaggagc tccagtgggc agctccccag caccagccat gaactacgtg gggcagctgg    180

cggagacggt gtttgggacg gtgaaggagc tgtaccgggg cctgaaccca gccacactga    240

gcggcggcat tgacgtgctg gtggtgaagc aggtggacgg ctcgttccgg tgctcaccct    300

tccacgtgcg ttttggcaag ctgggcgtcc tgcggtcgcg ggagaaggtg gtagacattg    360

agctcaatgg ggagcctgtg gacttgcaca tgaagcttgg ggacagcggg gaggccttct    420

ttgttcagga gctggagagc gatgatgaac atgtgcctcc cggcctgtgc acctcaccca    480

tcccttgggg gggtctgtct ggcttcccct cggactccca gctgggcact gccagtgagc    540

ctgagggcct cgtcatggca ggcacggcct ccactgggcg gaggaagagg cgtcgcagga    600

ggaaacccaa gcagaaagag gatgcagtgg caactgattc tagtccagag gaactggagg    660

caggcgctga gacagtgtcc agttggaaga gaagtcttca ctgcagccca aagacatcta    720

cccctactcg gatggcgagt ggccccccca ggccagcctc tcagcaggtg agctaacatc    780

ccctaagagc gactcggagc tggaggtgcg gaccccggag cccagtcccc taagagccga    840

gtcccacatg cagtgggcct gggggaggct gcctaaggtg gccagagctg agcggcccga    900

gtcctcagtg gtccttgaag gcagagctgg ggcaacctct cctcctcggg gaggacccag    960

cactccctct acctctgtgg ctggcggcgt ggaccctttg ggactcccaa tccagcaaac   1020

agaggctggt gccgaccttc agcctgacac agaggatccc actctagtgg gtccccctct   1080

ccacacccca gagacagagg aaagcaagac tcagagctct ggggacatgg gcctccctcc   1140

tgcctccaag tcatggagct gggccactct ggaggttcca gttcccaccg ggcagccaga   1200

gagggtctcc agggggaaag gctccccaaa gagaagccag cacctgggcc ccagtgacat   1260

ctacctggat gacttgccct ccctggactc tgagaatgca gcgctttact tcccccaaag   1320

tgactctggg ctgggggcca gaagatggag tgaacccagc agtcagaagt ccctgaggga   1380

ccccaaccct gaacatgaac ctgaacccac tctggacaca gtggatacaa tagcactgtc   1440

cctctgtggt ggactggctg acagccggga catctcccta ggtatgttcg accatggcca   1500

agcccttttg agggctggtg ctgagcccag aggatgggga gggcagggaa gactgtgagg   1560

gtggggcagt agaggtgaga ggctgggctt ccctgcagct ctctgccctg tgcagtccac   1620

actccgccag caggggctgg accttcccaa gtccccatga agcaaaatgc ttgacgctaa   1680

gttgtgagtt atcctgtgaa tcctggggtg ggaacaggtg taaaaaccac aggtagggag   1740

gagcactgcc aggttacaaa gccaaccgac aggaggtgag cagcagagtg gggagcacca   1800

gggggctggg gcagcgggtc acatgggatg tgccagcctc acccctcact ctgcctctgt   1860

gcccagagaa attcaaccag cacagcgtct cttaccagga cctcaccaaa aaccccggac   1920

ttttggatga cccaaaccta gtggtgaaaa tcaatggaaa gcattataac tgggctgtgg   1980

ctgcccccat gatcctctcc ctgcaagcct tccagaaaaa cttgcccaag agcaccatgg   2040

acaagctgga gagggagaag atgccccgga agggtgggcg atggtggttt tcctggcgac   2100

gcagggactt cctggccgag gagcgcagtg cccagaagga gaagactgca gccaaggagc   2160

agcaggggga gaagacagaa gtcctgagca gtgatgacga tgccccagac agccctgtga   2220

tcctggagat cccctccttg ccaccctcca ctccaccctc cactcctacc tacaagaagt   2280

ccctccgcct ctcctccgat cagatccggc gcctgaacct gcaagaaggt gccaatgatg   2340

tggtcttcag cgtgaccact cagtaccagg gcacctgccg ctgcaaggcc accatctacc   2400

tgtggaaatg ggacgacaag gtggtcatct ctgacatcga cggcaccatc accaagtcag   2460

atgctctggg ccatatcctg ccccagctgg ggaaagactg gacacaccag ggcatcacca   2520

gtctctatca caaaatccaa ctgtgagtgc ctgggctggg gctggggctg aggcgaggcc   2580

cccagctcta gagagggagt gacaggacag gacatcttgg ggaccagcag ggcccacaag   2640

gcaggctgcc agggcaggtg cctggagtgc tgagacctct ctattggccc gcagttctgg   2700

gaaaggctca tcccctgggg ctgtgttcta ggatcagggc ccacctactg gcctgcagcc   2760

ggaggggagg ccctctccat cctggtccac ccaggcctca ggactctgtg caccgtccag   2820

ctgagtccac tgcctggccg ttctcttcaa gtcccctccc tgcaaaggtt ggaacatcag   2880

agtcccacag ttgggctggg caggctaaag ccagagaaac agatgggggc tggctggtct   2940

ctgatggctc tatgccaccc tgtcccccac tctcagaaat gggtacaagt tcctgtactg   3000

ctcggcgcgg gccattggca tggcggacct caccaagggg tacctgcagt gggtgagcga   3060

ggggggctgt agcctcccca agggccccat ccttctgtct cccagcagcc tcttctctgc   3120

cctccacagg taaccacccc tacacataca agcccgtggc cccctggtgg ggaaaggcag   3180

gcccactgcc aggccagcct tagcaggctg gcattaagct ctcaggtggc aaggagggtg   3240

gggtcagacc ccccatcacc tgagcctgcc atcccctctg gcttcttccc tactttggcc   3300

cccttccctg ctgtggttct ggccacccca gagaggtgat cgagaagaaa ccagaggtgt   3360

tcaaggtcgc ctgcctgagt gacatccagc agctgtttct gccccacgga cagcccttct   3420

atgctgcctt tgggaatagg cccaatgatg tctttgccta ccggcaggtg ggcctgcctg   3480

agtcacgcat cttcacagtc aacccccggg gagagctcat ccaggagctc ataaagaacc   3540

acaaatccac gtatgagcgg cttggtgaag tggtcgagct cctcttccca cctgtggccc   3600

gtggccccag cacagacctg gccaaccctg aatacagtaa cttctgctac tggcgggagc   3660

cactgcctgc tgtggacctt gataccctgg actgaacctg ccctggctgg ctcctcctcc   3720

ctggcccggc ccaggactgg ctaggtgtcc tggggtatag gagggtggga attggagtgt   3780

catggggcaa acccactgaa ggggaaggag gaggctgcag gttggttggc agctagagag   3840

actcccccat cttccccgtc atatttttgc cagctaagct gcagctgctc caggcgtcag   3900

tgtggcactg tcctggggca attagcttgt catctgggcc cttgcagggt tctttttttt   3960

tttttttttt tttttttcct gagacagggt cttgttctgt tgcccaggct ggagtgcagt   4020

ggcatgatct ctcggctcac tgcaacctcc gcctcccggg ttcaagcgat tcacctgcct   4080

cagcctccca agtagctggg attacaggcg tgtaccacca cgcctggcta attttcgtgt   4140

ttttagtaga gatgggtttt caccacattg gccaggctgg tctcgaactc ctgacctcaa   4200

gtgatttgcc cacctcggcc tcccaaagtg ctgggattac aggcatgagc taccatgcca   4260

ggcctccttg cagggttttc tatgcccttg atatctgtct ccctgtcaac ctgggacctt   4320

gctgtaagtc ttgataggac agggagaaga gggaggccct accgaggctc gaggcttcag   4380

tgaagggtga cagcagtggg agtgtggtac agcctctgga aggacacagt gttctccccg   4440

ccccttgtct gggagccagg actgtaccct ccgaagccag acatcactgc caacatatcc   4500

cccttgctgg tgccctggca tctcagcaca tgacacacac ccacacctgc aggctgtggt   4560

tccggcttgg cctgctcccc gtccggctgc tgccgctgcc tctctccaga cctcgcttaa   4620

ggacagtccc aaactcagct ggggcaggtg ttggcctgaa agtcctcccc cagcctctgc   4680

tggccagctt ggtgctcaca gctgctgggt aagctcttgc ctaaggagct gtgggaagca   4740

gggctgatgc cccagcaacc tctcctccca ctgtctttga agaaagtagc tttagaccgg   4800

ctaaaagctt taatccagag cctgccctac tctgatagta ccagagtgga gggcagaata   4860

ccaaatgtcc aggaaccaaa ggcagggctg tggggacctg aagagcagca cagtggggcc   4920

cgtgctgctg tgggggaaac tgaggctggg agcctcagca gagaccggtg tcaagagtct   4980

ctgggaactg cataggcctg aggaacatgc attttcaagt tgtccattga tggtttcgta   5040

cctgaatttc tcaccttttg tgaacatctt gggagggtgg gggttttgca ggggtgttaa   5100

aagcaaggct tggagcccct ttcctccagc tggtggctcc ttctcagggc ctggcctcat   5160

tcaggccact ttgtagagaa atgccctgac ctcgcaggaa ggatttcccc acccccaagt   5220

ggaaggaaga ggacagtgtg ggcaccagag ggccctggaa acatcttagg ggaaggaaag   5280

gaaaaggata aatttggagt ggggggtctc taaacagatt gcctggattc cgttctttcc   5340

tggggttcta cagctgccta agccctcacc ttgggggagg atcaaaggga ataaagagaa   5400

ctcttggctg agtc                                                     5414


<210>  10146
<211>  236
<212>  PRT
<213>  Homo sapiens

<400>  10146

Met Gln Trp Ala Trp Gly Arg Leu Pro Lys Val Ala Arg Ala Glu Arg 
1               5                   10                  15


Pro Glu Ser Ser Val Val Leu Glu Gly Arg Ala Gly Ala Thr Ser Pro 
            20                  25                  30


Pro Arg Gly Gly Pro Ser Thr Pro Ser Thr Ser Val Ala Gly Gly Val 
        35                  40                  45


Asp Pro Leu Gly Leu Pro Ile Gln Gln Thr Glu Ala Gly Ala Asp Leu 
    50                  55                  60


Gln Pro Asp Thr Glu Asp Pro Thr Leu Val Gly Pro Pro Leu His Thr 
65                  70                  75                  80


Pro Glu Thr Glu Glu Ser Lys Thr Gln Ser Ser Gly Asp Met Gly Leu 
                85                  90                  95


Pro Pro Ala Ser Lys Ser Trp Ser Trp Ala Thr Leu Glu Val Pro Val 
            100                 105                 110


Pro Thr Gly Gln Pro Glu Arg Val Ser Arg Gly Lys Gly Ser Pro Lys 
        115                 120                 125


Arg Ser Gln His Leu Gly Pro Ser Asp Ile Tyr Leu Asp Asp Leu Pro 
    130                 135                 140


Ser Leu Asp Ser Glu Asn Ala Ala Leu Tyr Phe Pro Gln Ser Asp Ser 
145                 150                 155                 160


Gly Leu Gly Ala Arg Arg Trp Ser Glu Pro Ser Ser Gln Lys Ser Leu 
                165                 170                 175


Arg Asp Pro Asn Pro Glu His Glu Pro Glu Pro Thr Leu Asp Thr Val 
            180                 185                 190


Asp Thr Ile Ala Leu Ser Leu Cys Gly Gly Leu Ala Asp Ser Arg Asp 
        195                 200                 205


Ile Ser Leu Gly Met Phe Asp His Gly Gln Ala Leu Leu Arg Ala Gly 
    210                 215                 220


Ala Glu Pro Arg Gly Trp Gly Gly Gln Gly Arg Leu 
225                 230                 235


<210>  10147
<211>  577
<212>  DNA
<213>  Homo sapiens

<400>  10147
agaaggagtg gagccgtgct ctcaccctgt cttagaggac ccggaagcgc caagtgactg     60

agggccgaag acactcacct gtggagcctg tgcacgtagg tagaggcggc ggctctgagt    120

ccaggagctc cagtgggcag ctccccagca ccagccatga actacgtggg gcagctggcg    180

gagacggtgt ttgggacggt gaaggagctg taccggggcc tgaacccagc cacactgagc    240

ggcggcattg acgtgctggt ggtgaagcag gtggacggct cgttccggtg ctcacccttc    300

cacgtgcgtt ttggcaagct gggcgtcctg cggtcgcggg agaaggtggt gagtgctcag    360

gctggctgag gtggctactg cagagtgggc tttttaagct ggggcagcca ctacagtccc    420

aggacaggac ctggggcctc ccttaggtgg ggatctgtcc tctggacagg cttcccttca    480

tttgtacttt ctttgaaggt ttttgggttg atttgggggt tttggtctgg gagggttcac    540

agttagtttc tcatggaaac agaccagtag ggctcat                             577


<210>  10148
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  10148

Met Asn Tyr Val Gly Gln Leu Ala Glu Thr Val Phe Gly Thr Val Lys 
1               5                   10                  15


Glu Leu Tyr Arg Gly Leu Asn Pro Ala Thr Leu Ser Gly Gly Ile Asp 
            20                  25                  30


Val Leu Val Val Lys Gln Val Asp Gly Ser Phe Arg Cys Ser Pro Phe 
        35                  40                  45


His Val Arg Phe Gly Lys Leu Gly Val Leu Arg Ser Arg Glu Lys Val 
    50                  55                  60


Val Ser Ala Gln Ala Gly 
65                  70


<210>  10149
<211>  4363
<212>  DNA
<213>  Homo sapiens

<400>  10149
cgaagacact cacctgtgga gcctgtgcac gtaggtagag gcggcggctc tgagtccagg     60

agctccagtg ggcagctccc cagcaccagc catgaactac gtggggcagc tggcggagac    120

ggtgtttggg acggtgaagg agctgtaccg gggcctgaac ccagccacac tgagcggcgg    180

cattgacgtg ctggtggtga agcaggtgga cggctcgttc cggtgctcac ccttccacgt    240

gcgttttggc aagctgggcg tcctgcggtc gcgggagaag gtggtagaca ttgagctcaa    300

tggggagcct gtggacttgc acatgaagct tggggacagc ggggaggcct tctttgttca    360

ggagctggag agcgatgatg aacatgtgcc tcccggcctg tgcacctcac ccatcccttg    420

ggggggtctg tctggcttcc cctcggactc ccagctgggc actgccagtg agcctgaggg    480

cctcgtcatg gcaggcacgg cctccactgg gcggaggaag aggcgtcgca ggaggaaacc    540

caagcagaaa gaggatgcag tggcaactga ttctagtcca gaggaactgg aggcaggcgc    600

tgagagtgag ctatccctgc cggaaaagct gaggccagag cccccaggtg tccagttgga    660

agagaagtct tcactgcagc ccaaagacat ctacccctac tcggatggcg agtggccccc    720

ccaggccagc ctctcagcag gtgagctaac atcccctaag agcgactcgg agctggaggt    780

gcggaccccg gagcccagtc ccctaagagc cgagtcccac atgcagtggg cctgggggag    840

gctgcctaag gtggccagag ctgagcggcc cgagtcctca gtggtccttg aaggcagagc    900

tggggcaacc tctcctcctc ggggaggacc cagcactccc tctacctctg tggctggcgg    960

cgtggaccct ttgggactcc caatccagca aacagaggct ggtgccgacc ttcagcctga   1020

cacagaggat cccactctag tgggtccccc tctccacacc ccagagacag aggaaagcaa   1080

gactcagagc tctggggaca tgggcctccc tcctgcctcc aagtcatgga gctgggccac   1140

tctggaggtt ccagttccca ccgggcagcc agagagggtc tccaggggga aaggctcccc   1200

aaagagaagc cagcacctgg gccccagtga catctacctg gatgacttgc cctccctgga   1260

ctctgagaat gcagcgcttt acttccccca aagtgactct gggctggggg ccagaagatg   1320

gagtgaaccc agcagtcaga agtccctgag ggaccccaac cctgaacatg aacctgaacc   1380

cactctggac acagtggata caatagcact gtccctctgt ggtggactgg ctgacagccg   1440

ggacatctcc ctagagaaat tcaaccagca cagcgtctct taccaggacc tcaccaaaaa   1500

ccccggactt ttggatgacc caaacctagt ggtgaaaatc aatggaaagc attataactg   1560

ggctgtggct gcccccatga tcctctccct gcaagccttc cagaaaaact tgcccaagag   1620

caccatggac aagctggaga gggagaagat gccccggaag ggtgggcgat ggtggttttc   1680

ctggcgacgc agggacttcc tggccgagga gcgcagtgcc cagaaggaga agactgcagc   1740

caaggagcag cagggggaga agacagaagt cctgagcagt gatgacgatg ccccagacag   1800

ccctgtgatc ctggagatcc cctccttgcc accctccact ccaccctcca ctcctaccta   1860

caagaagtcc ctccgcctct cctccgatca gatccggcgc ctgaacctgc aagaaggtgc   1920

caatgatgtg gtcttcagcg tgaccactca gtaccagggc acctgccgct gcaaggccac   1980

catctacctg tggaaatggg acgacaaggt ggtcatctct gacatcgacg gcaccatcac   2040

caagtcagat gctctgggcc atatcctgcc ccagctgggg aaagactgga cacaccaggg   2100

catcaccagt ctctatcaca aaatccaact aaatgggtac aagttcctgt actgctcggc   2160

gcgggccatt ggcatggcgg acctcaccaa ggggtacctg cagtgggtga gcgagggggg   2220

ctgtagcctc cccaagggcc ccatccttct gtctcccagc agcctcttct ctgccctcca   2280

cagagaggtg atcgagaaga aaccagaggt gttcaaggtc gcctgcctga gtgacatcca   2340

gcagctgttt ctgccccacg gacagccctt ctatgctgcc tttgggaata ggcccaatga   2400

tgtctttgcc taccggcagg tgggcctgcc tgagtcacgc atcttcacag tcaacccccg   2460

gggagagctc atccaggagc tcataaagaa ccacaaatcc acgtatgagc ggcttggtga   2520

agtggtcgag ctcctcttcc cacctgtggc ccgtggcccc agcacagacc tggccaaccc   2580

tgaatacagt aacttctgct actggcggga gccactgcct gctgtggacc ttgataccct   2640

ggactgaacc tgccctggct ggctcctcct ccctggcccg gcccaggact ggctaggtgt   2700

cctggggtat aggagggtgg gaattggagt gtcatggggc aaacccactg aaggggaagg   2760

aggaggctgc aggttggttg gcagctagag agactccccc atcttccccg tcatattttt   2820

gccagctaag ctgcagctgc tccaggcgtc agtgtggcac tgtcctgggg caattagctt   2880

gtcatctggg cccttgcagg gttctttttt tttttttttt tttttttttc ctgagacagg   2940

gtcttgttct gttgcccagg ctggagtgca gtggcatgat ctctcggctc actgcaacct   3000

ccgcctcccg ggttcaagcg attcacctgc ctcagcctcc caagtagctg ggattacagg   3060

cgtgtaccac cacgcctggc taattttcgt gtttttagta gagatgggtt ttcaccacat   3120

tggccaggct ggtctcgaac tcctgacctc aagtgatttg cccacctcgg cctcccaaag   3180

tgctgggatt acaggcatga gctaccatgc caggcctcct tgcagggttt tctatgccct   3240

tgatatctgt ctccctgtca acctgggacc ttgctgtaag tcttgatagg acagggagaa   3300

gagggaggcc ctaccgaggc tcgaggcttc agtgaagggt gacagcagtg ggagtgtggt   3360

acagcctctg gaaggacaca gtgttctccc cgccccttgt ctgggagcca ggactgtacc   3420

ctccgaagcc agacatcact gccaacatat cccccttgct ggtgccctgg catctcagca   3480

catgacacac acccacacct gcaggctgtg gttccggctt ggcctgctcc ccgtccggct   3540

gctgccgctg cctctctcca gacctcgctt aaggacagtc ccaaactcag ctggggcagg   3600

tgttggcctg aaagtcctcc cccagcctct gctggccagc ttggtgctca cagctgctgg   3660

gtaagctctt gcctaaggag ctgtgggaag cagggctgat gccccagcaa cctctcctcc   3720

cactgtcttt gaagaaagta gctttagacc ggctaaaagc tttaatccag agcctgccct   3780

actctgatag taccagagtg gagggcagaa taccaaatgt ccaggaacca aaggcagggc   3840

tgtggggacc tgaagagcag cacagtgggg cccgtgctgc tgtgggggaa actgaggctg   3900

ggagcctcag cagagaccgg tgtcaagagt ctctgggaac tgcataggcc tgaggaacat   3960

gcattttcaa gttgtccatt gatggtttcg tacctgaatt tctcaccttt tgtgaacatc   4020

ttgggagggt gggggttttg caggggtgtt aaaagcaagg cttggagccc ctttcctcca   4080

gctggtggct ccttctcagg gcctggcctc attcaggcca ctttgtagag aaatgccctg   4140

acctcgcagg aaggatttcc ccacccccaa gtggaaggaa gaggacagtg tgggcaccag   4200

agggccctgg aaacatctta ggggaaggaa aggaaaagga taaatttgga gtggggggtc   4260

tctaaacaga ttgcctggat tccgttcttt cctggggttc tacagctgcc taagccctca   4320

ccttggggga ggatcaaagg gaataaagag aactcttggc tga                     4363


<210>  10150
<211>  851
<212>  PRT
<213>  Homo sapiens

<400>  10150

Met Asn Tyr Val Gly Gln Leu Ala Glu Thr Val Phe Gly Thr Val Lys 
1               5                   10                  15


Glu Leu Tyr Arg Gly Leu Asn Pro Ala Thr Leu Ser Gly Gly Ile Asp 
            20                  25                  30


Val Leu Val Val Lys Gln Val Asp Gly Ser Phe Arg Cys Ser Pro Phe 
        35                  40                  45


His Val Arg Phe Gly Lys Leu Gly Val Leu Arg Ser Arg Glu Lys Val 
    50                  55                  60


Val Asp Ile Glu Leu Asn Gly Glu Pro Val Asp Leu His Met Lys Leu 
65                  70                  75                  80


Gly Asp Ser Gly Glu Ala Phe Phe Val Gln Glu Leu Glu Ser Asp Asp 
                85                  90                  95


Glu His Val Pro Pro Gly Leu Cys Thr Ser Pro Ile Pro Trp Gly Gly 
            100                 105                 110


Leu Ser Gly Phe Pro Ser Asp Ser Gln Leu Gly Thr Ala Ser Glu Pro 
        115                 120                 125


Glu Gly Leu Val Met Ala Gly Thr Ala Ser Thr Gly Arg Arg Lys Arg 
    130                 135                 140


Arg Arg Arg Arg Lys Pro Lys Gln Lys Glu Asp Ala Val Ala Thr Asp 
145                 150                 155                 160


Ser Ser Pro Glu Glu Leu Glu Ala Gly Ala Glu Ser Glu Leu Ser Leu 
                165                 170                 175


Pro Glu Lys Leu Arg Pro Glu Pro Pro Gly Val Gln Leu Glu Glu Lys 
            180                 185                 190


Ser Ser Leu Gln Pro Lys Asp Ile Tyr Pro Tyr Ser Asp Gly Glu Trp 
        195                 200                 205


Pro Pro Gln Ala Ser Leu Ser Ala Gly Glu Leu Thr Ser Pro Lys Ser 
    210                 215                 220


Asp Ser Glu Leu Glu Val Arg Thr Pro Glu Pro Ser Pro Leu Arg Ala 
225                 230                 235                 240


Glu Ser His Met Gln Trp Ala Trp Gly Arg Leu Pro Lys Val Ala Arg 
                245                 250                 255


Ala Glu Arg Pro Glu Ser Ser Val Val Leu Glu Gly Arg Ala Gly Ala 
            260                 265                 270


Thr Ser Pro Pro Arg Gly Gly Pro Ser Thr Pro Ser Thr Ser Val Ala 
        275                 280                 285


Gly Gly Val Asp Pro Leu Gly Leu Pro Ile Gln Gln Thr Glu Ala Gly 
    290                 295                 300


Ala Asp Leu Gln Pro Asp Thr Glu Asp Pro Thr Leu Val Gly Pro Pro 
305                 310                 315                 320


Leu His Thr Pro Glu Thr Glu Glu Ser Lys Thr Gln Ser Ser Gly Asp 
                325                 330                 335


Met Gly Leu Pro Pro Ala Ser Lys Ser Trp Ser Trp Ala Thr Leu Glu 
            340                 345                 350


Val Pro Val Pro Thr Gly Gln Pro Glu Arg Val Ser Arg Gly Lys Gly 
        355                 360                 365


Ser Pro Lys Arg Ser Gln His Leu Gly Pro Ser Asp Ile Tyr Leu Asp 
    370                 375                 380


Asp Leu Pro Ser Leu Asp Ser Glu Asn Ala Ala Leu Tyr Phe Pro Gln 
385                 390                 395                 400


Ser Asp Ser Gly Leu Gly Ala Arg Arg Trp Ser Glu Pro Ser Ser Gln 
                405                 410                 415


Lys Ser Leu Arg Asp Pro Asn Pro Glu His Glu Pro Glu Pro Thr Leu 
            420                 425                 430


Asp Thr Val Asp Thr Ile Ala Leu Ser Leu Cys Gly Gly Leu Ala Asp 
        435                 440                 445


Ser Arg Asp Ile Ser Leu Glu Lys Phe Asn Gln His Ser Val Ser Tyr 
    450                 455                 460


Gln Asp Leu Thr Lys Asn Pro Gly Leu Leu Asp Asp Pro Asn Leu Val 
465                 470                 475                 480


Val Lys Ile Asn Gly Lys His Tyr Asn Trp Ala Val Ala Ala Pro Met 
                485                 490                 495


Ile Leu Ser Leu Gln Ala Phe Gln Lys Asn Leu Pro Lys Ser Thr Met 
            500                 505                 510


Asp Lys Leu Glu Arg Glu Lys Met Pro Arg Lys Gly Gly Arg Trp Trp 
        515                 520                 525


Phe Ser Trp Arg Arg Arg Asp Phe Leu Ala Glu Glu Arg Ser Ala Gln 
    530                 535                 540


Lys Glu Lys Thr Ala Ala Lys Glu Gln Gln Gly Glu Lys Thr Glu Val 
545                 550                 555                 560


Leu Ser Ser Asp Asp Asp Ala Pro Asp Ser Pro Val Ile Leu Glu Ile 
                565                 570                 575


Pro Ser Leu Pro Pro Ser Thr Pro Pro Ser Thr Pro Thr Tyr Lys Lys 
            580                 585                 590


Ser Leu Arg Leu Ser Ser Asp Gln Ile Arg Arg Leu Asn Leu Gln Glu 
        595                 600                 605


Gly Ala Asn Asp Val Val Phe Ser Val Thr Thr Gln Tyr Gln Gly Thr 
    610                 615                 620


Cys Arg Cys Lys Ala Thr Ile Tyr Leu Trp Lys Trp Asp Asp Lys Val 
625                 630                 635                 640


Val Ile Ser Asp Ile Asp Gly Thr Ile Thr Lys Ser Asp Ala Leu Gly 
                645                 650                 655


His Ile Leu Pro Gln Leu Gly Lys Asp Trp Thr His Gln Gly Ile Thr 
            660                 665                 670


Ser Leu Tyr His Lys Ile Gln Leu Asn Gly Tyr Lys Phe Leu Tyr Cys 
        675                 680                 685


Ser Ala Arg Ala Ile Gly Met Ala Asp Leu Thr Lys Gly Tyr Leu Gln 
    690                 695                 700


Trp Val Ser Glu Gly Gly Cys Ser Leu Pro Lys Gly Pro Ile Leu Leu 
705                 710                 715                 720


Ser Pro Ser Ser Leu Phe Ser Ala Leu His Arg Glu Val Ile Glu Lys 
                725                 730                 735


Lys Pro Glu Val Phe Lys Val Ala Cys Leu Ser Asp Ile Gln Gln Leu 
            740                 745                 750


Phe Leu Pro His Gly Gln Pro Phe Tyr Ala Ala Phe Gly Asn Arg Pro 
        755                 760                 765


Asn Asp Val Phe Ala Tyr Arg Gln Val Gly Leu Pro Glu Ser Arg Ile 
    770                 775                 780


Phe Thr Val Asn Pro Arg Gly Glu Leu Ile Gln Glu Leu Ile Lys Asn 
785                 790                 795                 800


His Lys Ser Thr Tyr Glu Arg Leu Gly Glu Val Val Glu Leu Leu Phe 
                805                 810                 815


Pro Pro Val Ala Arg Gly Pro Ser Thr Asp Leu Ala Asn Pro Glu Tyr 
            820                 825                 830


Ser Asn Phe Cys Tyr Trp Arg Glu Pro Leu Pro Ala Val Asp Leu Asp 
        835                 840                 845


Thr Leu Asp 
    850


<210>  10151
<211>  567
<212>  DNA
<213>  Homo sapiens

<400>  10151
ccgctgcaag gccaccatct acctgtggaa atgggacgac aaggtggtca tctctgacat     60

cgacggcacc atcaccaagt cagatgctct gggccatatc ctgccccagc tggggaaaga    120

ctggacacac cagggcatca ccagtctcta tcacaaaatc caactaaatg ggtacaagtt    180

cctgtactgc tcggcgcggg ccattggcat ggcggacctc accaaggggt acctgcagtg    240

gagaggtgat cgagaagaaa ccagaggtgt tcaaggtcgc ctgcctgagt gacatccagc    300

agctgtttct gccccacgga cagcccttct atgctgcctt tgggaatagg cccaatgatg    360

tctttgccta ccggcaggtg ggcctgcctg agtcacgcat cttcacagtc aacccccggg    420

gagagctcat ccaggagctc ataaagaacc acaaatccac gtatgagcgg cttggtgaag    480

tggtcgagct cctcttccca cctgtggccc gtggccccag cacagacctg gccaaccctg    540

aatacagtaa cttctgctac tggcggg                                        567


<210>  10152
<211>  132
<212>  PRT
<213>  Homo sapiens

<400>  10152

Met Gly Thr Ser Ser Cys Thr Ala Arg Arg Gly Pro Leu Ala Trp Arg 
1               5                   10                  15


Thr Ser Pro Arg Gly Thr Cys Ser Gly Glu Val Ile Glu Lys Lys Pro 
            20                  25                  30


Glu Val Phe Lys Val Ala Cys Leu Ser Asp Ile Gln Gln Leu Phe Leu 
        35                  40                  45


Pro His Gly Gln Pro Phe Tyr Ala Ala Phe Gly Asn Arg Pro Asn Asp 
    50                  55                  60


Val Phe Ala Tyr Arg Gln Val Gly Leu Pro Glu Ser Arg Ile Phe Thr 
65                  70                  75                  80


Val Asn Pro Arg Gly Glu Leu Ile Gln Glu Leu Ile Lys Asn His Lys 
                85                  90                  95


Ser Thr Tyr Glu Arg Leu Gly Glu Val Val Glu Leu Leu Phe Pro Pro 
            100                 105                 110


Val Ala Arg Gly Pro Ser Thr Asp Leu Ala Asn Pro Glu Tyr Ser Asn 
        115                 120                 125


Phe Cys Tyr Trp 
    130


<210>  10153
<211>  1762
<212>  DNA
<213>  Homo sapiens

<400>  10153
cctgagacag ggtcttgttc tgttgcccag gctggagtgc agtggcatga tctctcggct     60

cactgcaacc tccgcctccc gggttcaagc gattcacctg cctcagcctc ccaagtagct    120

gggattacag gcgtgtacca ccacgcctgg ctaattttcg tgtttttagt agagatgggt    180

tttcaccaca ttggccaggc tggtctcgaa ctcctgacct caagtgattt gcccacctcg    240

gcctcccaaa gtgctgggat tacaggcatg agctaccatg ccaggcctcc ttgcagggtt    300

ttctatgccc ttgatatctg tctccctgtc aacctgggac cttgctgtaa gtcttgatag    360

gacagggaga agagggaggc cctaccgagg ctcgaggctt cagtgaaggg tgacagcagt    420

gggagtgtgg tacagcctct ggaaggacac agtgttctcc ccgccccttg tctgggagcc    480

aggactgtac cctccgaagc cagacatcac tgccaacata tcccccttgc tggtgccctg    540

gcatctcagc acatgacaca cacccacacc tgcaggctgt ggttccggct tggcctgctc    600

cccgtccggc tgctgccgct gcctctctcc agacctcgct taaggacagt cccaaactca    660

gctggggcag gtgttggcct gaaagtcctc ccccagcctc tgctggccag cttggtgctc    720

acagctgctg ggtaagctct tgcctaagga gctgtgggaa gcagggctga tgccccagca    780

acctctcctc ccactgtctt tgaagaaagt agctttagac cggctaaaag ctttaatcca    840

gagcctgccc tactctgata gtaccagagt ggagggcaga ataccaaatg tccaggaacc    900

aaaggcaggg ctgtggggac ctgaagagca gcacagtggg gcccgtgctg ctgtggggga    960

aactgaggct gggagcctca gcagagaccg gtgtcaagag tctctgggaa ctgcataggc   1020

ctgaggatca aagggaataa agagaactct tggctgagtc tttgtgcttc tgttctgtcc   1080

tgaaggacac gtgaggagcc agaaacatct ggcagcctct ggtccttagt tcagatacaa   1140

catccatgaa gctgccaggt gtgaggagag ttccagtggg catcaccttc ctgcacaaac   1200

ctagtcctga tggctgcgaa gagaagccga ggggacaagg aacagaagcc accaagggct   1260

gtggactgtt gcttgtgggc acagggcaat gcggacaggc cactggctgt gggcctgtag   1320

gtctctgcac agttgctgag gctggtgctg actgcctgca gggtcctctc aaggccttac   1380

atacggacac tgatcaaggc cagtttgcca cagcagctgc ccctgccagc catgctcagg   1440

ccctgcagct ggctgtccag acactgattt gctgacagtg gaatgtgaac tctctcaagt   1500

ctaccctggc cttcaagcat gacatccttg ccttgaccgc tgtccggaac tgtccagttt   1560

ctgcagcact gtgcatgggt tttggtggct gggacagcca cgtggaggat tccctcagtg   1620

gcctccttag tgccatttgg gctagccagg gaaggctgga aggcgctgct ggataaggct   1680

gggctctggg gtgatgttcc ccgagttggt gggatctagg ggttgggtcc tggccagcct   1740

gtctagttgg cttgccctgg cc                                            1762


<210>  10154
<211>  50
<212>  PRT
<213>  Homo sapiens

<400>  10154

Met Ser Arg Asn Gln Arg Gln Gly Cys Gly Asp Leu Lys Ser Ser Thr 
1               5                   10                  15


Val Gly Pro Val Leu Leu Trp Gly Lys Leu Arg Leu Gly Ala Ser Ala 
            20                  25                  30


Glu Thr Gly Val Lys Ser Leu Trp Glu Leu His Arg Pro Glu Asp Gln 
        35                  40                  45


Arg Glu 
    50


<210>  10155
<211>  3854
<212>  DNA
<213>  Homo sapiens

<400>  10155
atgggccgcc gccgcctgct cgtctggctg tgcgccgtcg cggcgctgct ctcgggggcg     60

caggccaggg gcaccccgct cctggcgcgg cctgcgccgc ccggtgcctc ccgctacagt    120

ctctacacga cgggatggcg cccgcggctg cgcccggggc cgcacaaggc cctctgtgcc    180

tatgtggtgc acaggaatgt gacctgcatc ctacaggagg gagcggagag ctacgtaaag    240

gctgaatacc ggcagtgtag atgggggccc aagtgccccg ggacagtcac gtaccgcaca    300

gtactcagac ccaaatacaa ggttggccct gctggaggag tacgtggacc gacggctgca    360

ccgactctgg gggagcctgc tggatggctt tgagcagaag ctgcaaggcg tccagagtga    420

gtgtgacctg cgggtgcagg aggtacggcg gcaatgtgag gagggtcagg ccgccagccg    480

gaggctgcac cagagccttg atggccggga gctggccctg cgccaggagc tgtcacagct    540

gggcagccag ctgcagggcc tgagcgtgtc tggcaggggc agctgctgtg ggcaactagc    600

cttgatcaat gcccgtatgg atggccttga gagggccctg caggcagtca ccgagaccca    660

aaggggcccc ggtgccccgg ccggggatga gcttacgagg ctctctgctg ccatgctcga    720

gggaggtgtg gacgggctgc ttgagggtct ggagacgctc aatgggacag agggtggagc    780

aaggggatgc tgtctgaggt tggacatggg ggggtgggga gtgggcggct ttgggaccat    840

gctggaagag cgcgtgcaga gcctcgagga gcgcctagca acattggctg gggagctaag    900

ccatgacagc gcctctccgg gcaggtcagc tcggcccctt gtacagacag agctggctgt    960

gctagagcaa cggttggtct cactggagac ttcgtgcacc ccgagcacca cctcagccat   1020

cctggacagc ctcgtggcag aggtgaaggc ctggcagagc cggagcgagg ccctcctacg   1080

ccaggtggcc agccacgcag cactgctcca gcagctcaat ggcactgtgg ccgaggtcca   1140

gggacagctg gcagaaggga cgggcagctc acttcaaggc gagatcactc tgctcaaggt   1200

caatctgaac tcagtgagca agtcgctcac aggcctcagt gactctgtca gccagtactc   1260

tgatgccttc ttggctgcca acacgtccct ggatgagcgg gaacgcaagg tggaagccga   1320

agtccaggcc atccaggagc aggtcagcag ccaaggctcc aggcttcagg ctggccacag   1380

gcaggtcctg aacctgcgtg gggagctgga gcaactcaag gctggtgtgg ccaaggtggc   1440

cagtgggctg agccgctgcc aggacacagc ccagaaactt cagcacacag tgggacactt   1500

tgaccagcgg gtggcacaag tggagggtgc gtgcaggagg ctgggcctgc tggccgcggg   1560

cctggacagc ttgcccactg agccactgag gcccagagag ggcctgtgga gccatgtgga   1620

ccagctgaat cgtacgctgg cccagcacac gcaggacatt gcccgcctcc gggatgacct   1680

actggactgc caggcccagc tggctgagca ggtgcggcca gggcaagcca actagacagg   1740

ctggccagga cccaacccct agatcccacc aactcgggga acatcacccc agagcccagc   1800

cttatccagc agcgccttcc agccttccct ggctagccca aatggcacta aggaggccac   1860

tgagggaatc ctccacgtgg ctgtcccagc caccaaaacc catgcacagt gctgcagaaa   1920

ctggacagtt ccggacagcg gtcaaggcaa ggatgtcatg cttgaaggcc agggtagact   1980

tgagagagtt cacattccac tgtcagcaaa tcagtgtctg gacagccagc tgcagggcct   2040

gagcatggct ggcaggggca gctgctgtgg caaactggcc ttgatcagtg tccgtatgta   2100

aggccttgag aggaccctgc aggcagtcag caccagcctc agcaactgtg cagagaccta   2160

caggcccaca gccagtggcc tgtccgcatt gccctgtgcc cacaagcaac agtccacagc   2220

ccttggtggc ttctgttcct tgtcccctcg gcttctcttc gcagccatca ggactaggtt   2280

tgtgcaggaa ggtgatgccc actggaactc tcctcacacc tggcagcttc atggatgttg   2340

tatctgaact aaggaccaga ggctgccaga tgtttctggc tcctcacgtg tccttcagga   2400

cagaacagaa gcacaaagac tcagccaaga gttctcttta ttccctttga tcctccccca   2460

aggtgagggc ttaggcagct gtagaacccc aggaaagaac ggaatccagg caatctgttt   2520

agagaccccc cactccaaat ttatcctttt cctttccttc ccctaagatg tttccagggc   2580

cctctggtgc ccacactgtc ctcttccttc cacttggggg tggggaaatc cttcctgcga   2640

ggtcagggca tttctctaca aagtggcctg aatgaggcca ggccctgaga aggagccacc   2700

agctggagga aaggggctcc aagccttgct tttaacaccc ctgcaaaacc cccaccctcc   2760

caagatgttc acaaaaggtg agaaattcag gtacgaaacc atcaatggac aacttgaaaa   2820

tgcatgttcc tcaggcctat gcagttccca gagactcttg acaccggtct ctgctgaggc   2880

tcccagcctc agtttccccc acagcagcac gggccccact gtgctgctct tcaggtcccc   2940

acagccctgc ctttggttcc tggacatttg gtattctgcc ctccactctg gtactatcag   3000

agtagggcag gctctggatt aaagctttta gccggtctaa agctactttc ttcaaagaca   3060

gtgggaggag aggttgctgg ggcatcagcc ctgcttccca cagctcctta ggcaagagct   3120

tacccagcag ctgtgagcac caagctggcc agcagaggct gggggaggac tttcaggcca   3180

acacctgccc cagctgagtt tgggactgtc cttaagcgag gtctggagag aggcagcggc   3240

agcagccgga cggggagcag gccaagccgg aaccacagcc tgcaggtgtg ggtgtgtgtc   3300

atgtgctgag atgccagggc accagcaagg gggatatgtt ggcagtgatg tctggcttcg   3360

gagggtacag tcctggctcc cagacaaggg gcggggagaa cactgtgtcc ttccagaggc   3420

tgtaccacac tcccactgct gtcacccttc actgaagcct cgagcctcgg tagggcctcc   3480

ctcttctccc tgtcctatca agacttacag caaggtccca ggttgacagg gagacagata   3540

tcaagggcat agaaaaccct gcaaggaggc ctggcatggt agctcatgcc tgtaatccca   3600

gcactttggg aggccgaggt gggcaaatca cttgaggtca ggagttcgag accagcctgg   3660

ccaatgtggt gaaaacccat ctctactaaa aacacgaaaa ttagccaggc gtggtggtac   3720

acgcctgtaa tcccagctac ttgggaggct gaggcaggtg aatcgcttga acccgggagg   3780

cggaggttgc agtgagccga gagatcatgc cactgcactc cagcctgggc aacagaacaa   3840

gaccctgtct cagg                                                     3854


<210>  10156
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  10156

Met Gly Arg Arg Arg Leu Leu Val Trp Leu Cys Ala Val Ala Ala Leu 
1               5                   10                  15


Leu Ser Gly Ala Gln Ala Arg Gly Thr Pro Leu Leu Ala Arg Pro Ala 
            20                  25                  30


Pro Pro Gly Ala Ser Arg Tyr Ser Leu Tyr Thr Thr Gly Trp Arg Pro 
        35                  40                  45


Arg Leu Arg Pro Gly Pro His Lys Ala Leu Cys Ala Tyr Val Val His 
    50                  55                  60


Arg Asn Val Thr Cys Ile Leu Gln Glu Gly Ala Glu Ser Tyr Val Lys 
65                  70                  75                  80


Ala Glu Tyr Arg Gln Cys Arg Trp Gly Pro Lys Cys Pro Gly Thr Val 
                85                  90                  95


Thr Tyr Arg Thr Val Leu Arg Pro Lys Tyr Lys Val Gly Pro Ala Gly 
            100                 105                 110


Gly Val Arg Gly Pro Thr Ala Ala Pro Thr Leu Gly Glu Pro Ala Gly 
        115                 120                 125


Trp Leu 
    130


<210>  10157
<211>  4644
<212>  DNA
<213>  Homo sapiens

<400>  10157
cgcctcccct ccgcggcccc agccgctagc agcgccggcc actccgcggg acgcagccgc     60

cgcgaagcgc caggcggccg ggccagcgag ctcgggggcc gaaggggacc ccgggaccct    120

cggggcggga cccgggccga ccagcggcgg gggcggcgcg gcgctgcagg cggacacccg    180

gcggggggca ccgcgcgggg ccgggcagag gcgcgggggc cgctatgggc cgccgccgcc    240

tgctcgtctg gctgtgcgcc gtcgcggcgc tgctctcggg ggcgcaggcc aggggcaccc    300

cgctcctggc gcggcctgcg ccgcccggtg cctcccgcta cagtctctac acgacgggat    360

ggcgcccgcg gctgcgcccg gggccgcaca aggccctctg tgcctatgtg gtgcacagga    420

atgtgacctg catcctacag gagggagcgg agagctacgt aaaggctgaa taccggcagt    480

gtagatgggg gcccaagtgc cccgggacag tcacgtaccg cacagtactc agacccaaat    540

acaaggttgg ctacaagaca gtgacagacc tcgcctggcg ttgctgtccc ggcttcactg    600

ggaaacgctg ccctgagcac ctcacggacc atggggctgc ctcaccccag ctggagcctg    660

agcctcagat tccttcaggg cagctggacc caggccccag gcccccttcc tacagcagag    720

cagcccccag ccctcatgga aggaaaggcc cagggctgtt tggtgagcgg ctggaacgcc    780

tggagggtga tgtccagcgc ctggctcaaa catatggtac cctcagtggc ctggtggcta    840

gccacgagga tcccaacagg atgactggtg gccccagggc tcctgctgtc cctgtgggct    900

ttggggtcat ccctgagggg cttgtgggcc caggagacag agccagaggg ccactaacac    960

ctcccttaga cgagatccta agcaaggtga cagaggtgag caacactctt cagaccaagg   1020

tgcagcttct agacaaggtg catgggctgg cacttggcca tgaggcccac ctgcagcggc   1080

tgcgggaagc cccaccatcc ccgctcacct ccctggccct gctggaggag tacgtggacc   1140

gacggctgca ccgactctgg gggagcctgc tggatggctt tgagcagaag ctgcaaggcg   1200

tccagagtga gtgtgacctg cgggtgcagg aggtacggcg gcaatgtgag gagggtcagg   1260

ccgccagccg gaggctgcac cagagccttg atggccggga gctggccctg cgccaggagc   1320

tgtcacagct gggcagccag ctgcagggcc tgagcgtgtc tggcaggggc agctgctgtg   1380

ggcaactagc cttgatcaat gcccgtatgg atggccttga gagggccctg caggcagtca   1440

ccgagaccca aaggggcccc ggtgccccgg ccggggatga gcttacgagg ctctctgctg   1500

ccatgctcga gggaggtgtg gacgggctgc ttgagggtct ggagacgctc aatgggacag   1560

agggtggagc aaggggatgc tgtctgaggt tggacatggg ggggtgggga gtgggcggct   1620

ttgggaccat gctggaagag cgcgtgcaga gcctcgagga gcgcctagca acattggctg   1680

gggagctaag ccatgacagc gcctctccgg gcaggtcagc tcggcccctt gtacagacag   1740

agctggctgt gctagagcaa cggttggtct cactggagac ttcgtgcacc ccgagcacca   1800

cctcagccat cctggacagc ctcgtggcag aggtgaaggc ctggcagagc cggagcgagg   1860

ccctcctacg ccaggtggcc agccacgcag cactgctcca gcagctcaat ggcactgtgg   1920

ccgaggtcca gggacagctg gcagaaggga cgggcagctc acttcaaggc gagatcactc   1980

tgctcaaggt caatctgaac tcagtgagca agtcgctcac aggcctcagt gactctgtca   2040

gccagtactc tgatgccttc ttggctgcca acacgtccct ggatgagcgg gaacgcaagg   2100

tggaagccga agtccaggcc atccaggagc aggtcagcag ccaaggctcc aggcttcagg   2160

ctggccacag gcaggtcctg aacctgcgtg gggagctgga gcaactcaag gctggtgtgg   2220

ccaaggtggc cagtgggctg agccgctgcc aggacacagc ccagaaactt cagcacacag   2280

tgggacactt tgaccagcgg gtggcacaag tggagggtgc gtgcaggagg ctgggcctgc   2340

tggccgcggg cctggacagc ttgcccactg agccactgag gcccagagag ggcctgtgga   2400

gccatgtgga ccagctgaat cgtacgctgg cccagcacac gcaggacatt gcccgcctcc   2460

gggatgacct actggactgc caggcccagc tggctgagca ggtgcggcca gggcaagcca   2520

actagacagg ctggccagga cccaacccct agatcccacc aactcgggga acatcacccc   2580

agagcccagc cttatccagc agcgccttcc agccttccct ggctagccca aatggcacta   2640

aggaggccac tgagggaatc ctccacgtgg ctgtcccagc caccaaaacc catgcacagt   2700

gctgcagaaa ctggacagtt ccggacagcg gtcaaggcaa ggatgtcatg cttgaaggcc   2760

agggtagact tgagagagtt cacattccac tgtcagcaaa tcagtgtctg gacagccagc   2820

tgcagggcct gagcatggct ggcaggggca gctgctgtgg caaactggcc ttgatcagtg   2880

tccgtatgta aggccttgag aggaccctgc aggcagtcag caccagcctc agcaactgtg   2940

cagagaccta caggcccaca gccagtggcc tgtccgcatt gccctgtgcc cacaagcaac   3000

agtccacagc ccttggtggc ttctgttcct tgtcccctcg gcttctcttc gcagccatca   3060

ggactaggtt tgtgcaggaa ggtgatgccc actggaactc tcctcacacc tggcagcttc   3120

atggatgttg tatctgaact aaggaccaga ggctgccaga tgtttctggc tcctcacgtg   3180

tccttcagga cagaacagaa gcacaaagac tcagccaaga gttctcttta ttccctttga   3240

tcctccccca aggtgagggc ttaggcagct gtagaacccc aggaaagaac ggaatccagg   3300

caatctgttt agagaccccc cactccaaat ttatcctttt cctttccttc ccctaagatg   3360

tttccagggc cctctggtgc ccacactgtc ctcttccttc cacttggggg tggggaaatc   3420

cttcctgcga ggtcagggca tttctctaca aagtggcctg aatgaggcca ggccctgaga   3480

aggagccacc agctggagga aaggggctcc aagccttgct tttaacaccc ctgcaaaacc   3540

cccaccctcc caagatgttc acaaaaggtg agaaattcag gtacgaaacc atcaatggac   3600

aacttgaaaa tgcatgttcc tcaggcctat gcagttccca gagactcttg acaccggtct   3660

ctgctgaggc tcccagcctc agtttccccc acagcagcac gggccccact gtgctgctct   3720

tcaggtcccc acagccctgc ctttggttcc tggacatttg gtattctgcc ctccactctg   3780

gtactatcag agtagggcag gctctggatt aaagctttta gccggtctaa agctactttc   3840

ttcaaagaca gtgggaggag aggttgctgg ggcatcagcc ctgcttccca cagctcctta   3900

ggcaagagct tacccagcag ctgtgagcac caagctggcc agcagaggct gggggaggac   3960

tttcaggcca acacctgccc cagctgagtt tgggactgtc cttaagcgag gtctggagag   4020

aggcagcggc agcagccgga cggggagcag gccaagccgg aaccacagcc tgcaggtgtg   4080

ggtgtgtgtc atgtgctgag atgccagggc accagcaagg gggatatgtt ggcagtgatg   4140

tctggcttcg gagggtacag tcctggctcc cagacaaggg gcggggagaa cactgtgtcc   4200

ttccagaggc tgtaccacac tcccactgct gtcacccttc actgaagcct cgagcctcgg   4260

tagggcctcc ctcttctccc tgtcctatca agacttacag caaggtccca ggttgacagg   4320

gagacagata tcaagggcat agaaaaccct gcaaggaggc ctggcatggt agctcatgcc   4380

tgtaatccca gcactttggg aggccgaggt gggcaaatca cttgaggtca ggagttcgag   4440

accagcctgg ccaatgtggt gaaaacccat ctctactaaa aacacgaaaa ttagccaggc   4500

gtggtggtac acgcctgtaa tcccagctac ttgggaggct gaggcaggtg aatcgcttga   4560

acccgggagg cggaggttgc agtgagccga gagatcatgc cactgcactc cagcctgggc   4620

aacagaacaa gaccctgtct cagg                                          4644


<210>  10158
<211>  766
<212>  PRT
<213>  Homo sapiens

<400>  10158

Met Gly Arg Arg Arg Leu Leu Val Trp Leu Cys Ala Val Ala Ala Leu 
1               5                   10                  15


Leu Ser Gly Ala Gln Ala Arg Gly Thr Pro Leu Leu Ala Arg Pro Ala 
            20                  25                  30


Pro Pro Gly Ala Ser Arg Tyr Ser Leu Tyr Thr Thr Gly Trp Arg Pro 
        35                  40                  45


Arg Leu Arg Pro Gly Pro His Lys Ala Leu Cys Ala Tyr Val Val His 
    50                  55                  60


Arg Asn Val Thr Cys Ile Leu Gln Glu Gly Ala Glu Ser Tyr Val Lys 
65                  70                  75                  80


Ala Glu Tyr Arg Gln Cys Arg Trp Gly Pro Lys Cys Pro Gly Thr Val 
                85                  90                  95


Thr Tyr Arg Thr Val Leu Arg Pro Lys Tyr Lys Val Gly Tyr Lys Thr 
            100                 105                 110


Val Thr Asp Leu Ala Trp Arg Cys Cys Pro Gly Phe Thr Gly Lys Arg 
        115                 120                 125


Cys Pro Glu His Leu Thr Asp His Gly Ala Ala Ser Pro Gln Leu Glu 
    130                 135                 140


Pro Glu Pro Gln Ile Pro Ser Gly Gln Leu Asp Pro Gly Pro Arg Pro 
145                 150                 155                 160


Pro Ser Tyr Ser Arg Ala Ala Pro Ser Pro His Gly Arg Lys Gly Pro 
                165                 170                 175


Gly Leu Phe Gly Glu Arg Leu Glu Arg Leu Glu Gly Asp Val Gln Arg 
            180                 185                 190


Leu Ala Gln Thr Tyr Gly Thr Leu Ser Gly Leu Val Ala Ser His Glu 
        195                 200                 205


Asp Pro Asn Arg Met Thr Gly Gly Pro Arg Ala Pro Ala Val Pro Val 
    210                 215                 220


Gly Phe Gly Val Ile Pro Glu Gly Leu Val Gly Pro Gly Asp Arg Ala 
225                 230                 235                 240


Arg Gly Pro Leu Thr Pro Pro Leu Asp Glu Ile Leu Ser Lys Val Thr 
                245                 250                 255


Glu Val Ser Asn Thr Leu Gln Thr Lys Val Gln Leu Leu Asp Lys Val 
            260                 265                 270


His Gly Leu Ala Leu Gly His Glu Ala His Leu Gln Arg Leu Arg Glu 
        275                 280                 285


Ala Pro Pro Ser Pro Leu Thr Ser Leu Ala Leu Leu Glu Glu Tyr Val 
    290                 295                 300


Asp Arg Arg Leu His Arg Leu Trp Gly Ser Leu Leu Asp Gly Phe Glu 
305                 310                 315                 320


Gln Lys Leu Gln Gly Val Gln Ser Glu Cys Asp Leu Arg Val Gln Glu 
                325                 330                 335


Val Arg Arg Gln Cys Glu Glu Gly Gln Ala Ala Ser Arg Arg Leu His 
            340                 345                 350


Gln Ser Leu Asp Gly Arg Glu Leu Ala Leu Arg Gln Glu Leu Ser Gln 
        355                 360                 365


Leu Gly Ser Gln Leu Gln Gly Leu Ser Val Ser Gly Arg Gly Ser Cys 
    370                 375                 380


Cys Gly Gln Leu Ala Leu Ile Asn Ala Arg Met Asp Gly Leu Glu Arg 
385                 390                 395                 400


Ala Leu Gln Ala Val Thr Glu Thr Gln Arg Gly Pro Gly Ala Pro Ala 
                405                 410                 415


Gly Asp Glu Leu Thr Arg Leu Ser Ala Ala Met Leu Glu Gly Gly Val 
            420                 425                 430


Asp Gly Leu Leu Glu Gly Leu Glu Thr Leu Asn Gly Thr Glu Gly Gly 
        435                 440                 445


Ala Arg Gly Cys Cys Leu Arg Leu Asp Met Gly Gly Trp Gly Val Gly 
    450                 455                 460


Gly Phe Gly Thr Met Leu Glu Glu Arg Val Gln Ser Leu Glu Glu Arg 
465                 470                 475                 480


Leu Ala Thr Leu Ala Gly Glu Leu Ser His Asp Ser Ala Ser Pro Gly 
                485                 490                 495


Arg Ser Ala Arg Pro Leu Val Gln Thr Glu Leu Ala Val Leu Glu Gln 
            500                 505                 510


Arg Leu Val Ser Leu Glu Thr Ser Cys Thr Pro Ser Thr Thr Ser Ala 
        515                 520                 525


Ile Leu Asp Ser Leu Val Ala Glu Val Lys Ala Trp Gln Ser Arg Ser 
    530                 535                 540


Glu Ala Leu Leu Arg Gln Val Ala Ser His Ala Ala Leu Leu Gln Gln 
545                 550                 555                 560


Leu Asn Gly Thr Val Ala Glu Val Gln Gly Gln Leu Ala Glu Gly Thr 
                565                 570                 575


Gly Ser Ser Leu Gln Gly Glu Ile Thr Leu Leu Lys Val Asn Leu Asn 
            580                 585                 590


Ser Val Ser Lys Ser Leu Thr Gly Leu Ser Asp Ser Val Ser Gln Tyr 
        595                 600                 605


Ser Asp Ala Phe Leu Ala Ala Asn Thr Ser Leu Asp Glu Arg Glu Arg 
    610                 615                 620


Lys Val Glu Ala Glu Val Gln Ala Ile Gln Glu Gln Val Ser Ser Gln 
625                 630                 635                 640


Gly Ser Arg Leu Gln Ala Gly His Arg Gln Val Leu Asn Leu Arg Gly 
                645                 650                 655


Glu Leu Glu Gln Leu Lys Ala Gly Val Ala Lys Val Ala Ser Gly Leu 
            660                 665                 670


Ser Arg Cys Gln Asp Thr Ala Gln Lys Leu Gln His Thr Val Gly His 
        675                 680                 685


Phe Asp Gln Arg Val Ala Gln Val Glu Gly Ala Cys Arg Arg Leu Gly 
    690                 695                 700


Leu Leu Ala Ala Gly Leu Asp Ser Leu Pro Thr Glu Pro Leu Arg Pro 
705                 710                 715                 720


Arg Glu Gly Leu Trp Ser His Val Asp Gln Leu Asn Arg Thr Leu Ala 
                725                 730                 735


Gln His Thr Gln Asp Ile Ala Arg Leu Arg Asp Asp Leu Leu Asp Cys 
            740                 745                 750


Gln Ala Gln Leu Ala Glu Gln Val Arg Pro Gly Gln Ala Asn 
        755                 760                 765


<210>  10159
<211>  1619
<212>  DNA
<213>  Homo sapiens

<400>  10159
tcgaactcct gacctcaagt gatttgccca cctcggcctc ccaaagtgct gggattacag     60

gcatgagcta ccatgccagg cctccttgca gggttttcta tgcccttgat atctgtctcc    120

ctgtcaacct gggaccttgc tgtaagtctt gataggacag ggagaagagg gaggccctac    180

cgaggctcga ggcttcagtg aagggtgaca gcagtgggag tgtggtacag cctctggaag    240

gacacagtgt tctccccgcc ccttgtctgg gagccaggac tgtaccctcc gaagccagac    300

atcactgcca acatatcccc cttgctggtg ccctggcatc tcagcacatg acacacaccc    360

acacctgcag gctgtggttc cggcttggcc tgctccccgt ccggctgctg ccgctgcctc    420

tctccagacc tcgcttaagg acagtcccaa actcagctgg ggcaggtgtt ggcctgaaag    480

tcctccccca gcctctgctg gccagcttgg tgctcacagc tgctgggtaa gctcttgcct    540

aaggagctgt gggaagcagg gctgatgccc cagcaacctc tcctcccact gtctttgaag    600

aaagtagctt tagaccggct aaaagcttta atccagagcc tgccctactc tgatagtacc    660

agagtggagg gcagaatacc aaatgtccag gaaccaaagg cagggctgtg gggacctgaa    720

gagcagcaca gtggggcccg tgctgctgtg ggggaaactg aggctgggag cctcagcaga    780

gaccggtgtc aagagtctct gggaactgca taggcctgag gaacatgcat tttcaagttg    840

tccattgatg gtttcgtacc tgaatttctc accttggggg aggatcaaag ggaataaaga    900

gaactcttgg ctgagtcttt gtgcttctgt tctgtcctga aggacacgtg aggagccaga    960

aacatctggc agcctctggt ccttagttca gatacaacat ccatgaagct gccaggtgtg   1020

aggagagttc cagtgggcat caccttcctg cacaaaccta gtcctgatgg ctgcgaagag   1080

aagccgaggg gacaaggaac agaagccacc aagggctgtg gactgttgct tgtgggcaca   1140

gggcaatgcg gacaggccac tggctgtggg cctgtaggtc tctgcacagt tgctgaggct   1200

ggtgctgact gcctgcaggg tcctctcaag gccttacata cggacactga tcaaggccag   1260

tttgccacag cagctgcccc tgccagccat gctcaggccc tgcagctggc tgtccagaca   1320

ctgatttgct gacagtggaa tgtgaactct ctcaagtcta ccctggcctt caagcatgac   1380

atccttgcct tgaccgctgt ccggaactgt ccagtttctg cagcactgtg catgggtttt   1440

ggtggctggg acagccacgt ggaggattcc ctcagtggcc tccttagtgc catttgggct   1500

agccagggaa ggctggaagg cgctgctgga taaggctggg ctctggggtg atgttccccg   1560

agttggtggg atctaggggt tgggtcctgg ccagcctgtc tagttggctt gccctggcc    1619


<210>  10160
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  10160

Met Ser Arg Asn Gln Arg Gln Gly Cys Gly Asp Leu Lys Ser Ser Thr 
1               5                   10                  15


Val Gly Pro Val Leu Leu Trp Gly Lys Leu Arg Leu Gly Ala Ser Ala 
            20                  25                  30


Glu Thr Gly Val Lys Ser Leu Trp Glu Leu His Arg Pro Glu Glu His 
        35                  40                  45


Ala Phe Ser Ser Cys Pro Leu Met Val Ser Tyr Leu Asn Phe Ser Pro 
    50                  55                  60


Trp Gly Arg Ile Lys Gly Asn Lys Glu Asn Ser Trp Leu Ser Leu Cys 
65                  70                  75                  80


Ala Ser Val Leu Ser 
                85


<210>  10161
<211>  3037
<212>  DNA
<213>  Homo sapiens

<400>  10161
atgggccgcc gccgcctgct cgtctggctg tgcgccgtcg cggcgctgct ctcgggggcg     60

caggccaggg gcaccccgct cctggcgcgg cctgcgccgc ccggtgcctc ccgctacagt    120

ctctacacga cgggatggcg cccgcggctg cgcccggggc cgcacaaggc cctctgtgcc    180

tatgtggtgc acaggaatgt gacctgcatc ctacaggagg gagcggagag ctacgtaaag    240

gctgaatacc ggcagtgtag atgggggccc aagtgccccg ggacagtcac gtaccgcaca    300

gtactcagac ccaaatacaa ggttggccct gctggaggag tacgtggacc gacggctgca    360

ccgactctgg gggagcctgc tggatggctt tgagcagaag ctgcaaggcg tccagagtga    420

gtgtgacctg cgggtgcagg aggtacggcg gcaatgtgag gagggtcagg ccgccagccg    480

gaggctgcac cagagccttg atggccggga gctggccctg cgccaggagc tgtcacagct    540

gggcagccag ctgcagggcc tgagcgtgtc tggcaggggc agctgctgtg ggcaactagc    600

cttgatcaat gcccgtatgg atggccttga gagggccctg caggcagtca ccgagaccca    660

aaggggcccc ggtgccccgg ccggggatga gcttacgagg ctctctgctg ccatgctcga    720

gggaggtgtg gacgggctgc ttgagggtct ggagacgctc aatgggacag agggtggagc    780

aaggggatgc tgtctgaggt tggacatggg ggggtgggga gtgggcggct ttgggaccat    840

gctggaagag cgcgtgcaga gcctcgagga gcgcctagca acattggctg gggagctaag    900

ccatgacagc gcctctccgg gcaggtcagc tcggcccctt gtacagacag agctggctgt    960

gctagagcaa cggttggtct cactggagac ttcgtgcacc ccgagcacca cctcagccat   1020

cctggacagc ctcgtggcag aggtgaaggc ctggcagagc cggagcgagg ccctcctacg   1080

ccaggtggcc agccacgcag cactgctcca gcagctcaat ggcactgtgg ccgaggtcca   1140

gggacagctg gcagaaggga cgggcagctc acttcaaggc gagatcactc tgctcaaggt   1200

caatctgaac tcagtgagca agtcgctcac aggcctcagt gactctgtca gccagtactc   1260

tgatgccttc ttggctgcca acacgtccct ggatgagcgg gaacgcaagg tggaagccga   1320

agtccaggcc atccaggagc aggtcagcag ccaaggctcc aggcttcagg ctggccacag   1380

gcaggtcctg aacctgcgtg gggagctgga gcaactcaag gctggtgtgg ccaaggtggc   1440

cagtgggctg agccgctgcc aggacacagc ccagaaactt cagcacacag tgggacactt   1500

tgaccagcgg gtggcacaag tggagggtgc gtgcaggagg ctgggcctgc tggccgcggg   1560

cctggacagc ttgcccactg agccactgag gcccagagag ggcctgtgga gccatgtgga   1620

ccagctgaat cgtacgctgg cccagcacac gcaggacatt gcccgcctcc gggatgacct   1680

actggactgc caggcccagc tggctgagca ggtgcggcca gggcaagcca actagacagg   1740

ctggccagga cccaacccct agatcccacc aactcgggga acatcacccc agagcccagc   1800

cttatccagc agcgccttcc agccttccct ggctagccca aatggcacta aggaggccac   1860

tgagggaatc ctccacgtgg ctgtcccagc caccaaaacc catgcacagt gctgcagaaa   1920

ctggacagtt ccggacagcg gtcaaggcaa ggatgtcatg cttgaaggcc agggtagact   1980

tgagagagtt cacattccac tgtcagcaaa tcagtgtctg gacagccagc tgcagggcct   2040

gagcatggct ggcaggggca gctgctgtgg caaactggcc ttgatcagtg tccgtatgta   2100

aggccttgag aggaccctgc aggcagtcag caccagcctc agcaactgtg cagagaccta   2160

caggcccaca gccagtggcc tgtccgcatt gccctgtgcc cacaagcaac agtccacagc   2220

ccttggtggc ttctgttcct tgtcccctcg gcttctcttc gcagccatca ggactaggtt   2280

tgtgcaggaa ggtgatgccc actggaactc tcctcacacc tggcagcttc atggatgttg   2340

tatctgaact aaggaccaga ggctgccaga tgtttctggc tcctcacgtg tccttcagga   2400

cagaacagaa gcacaaagac tcagccaaga gttctcttta ttccctttga tcctccccca   2460

aggtgagggc ttaggcagct gtagaacccc aggaaagaac ggaatccagg caatctgttt   2520

agagaccccc cactccaaat ttatcctttt cctttccttc ccctaagatg tttccagggc   2580

cctctggtgc ccacactgtc ctcttccttc cacttggggg tggggaaatc cttcctgcga   2640

ggtcagggca tttctctaca aagtggcctg aatgaggcca ggccctgaga aggagccacc   2700

agctggagga aaggggctcc aagccttgct tttaacaccc ctgcaaaacc cccaccctcc   2760

caagatgttc acaaaaggtg agaaattcag gtacgaaacc atcaatggac aacttgaaaa   2820

tgcatgttcc tcaggcctat gcagttccca gagactcttg acaccggtct ctgctgaggc   2880

tcccagcctc agtttccccc acagcagcac gggccccact gtgctgctct tcaggtcccc   2940

acagccctgc ctttggttcc tggacatttg gtattctgcc ctccactctg gtactatcag   3000

agtagggcag gctctggatt aaagctttta gccggtc                            3037


<210>  10162
<211>  130
<212>  PRT
<213>  Homo sapiens

<400>  10162

Met Gly Arg Arg Arg Leu Leu Val Trp Leu Cys Ala Val Ala Ala Leu 
1               5                   10                  15


Leu Ser Gly Ala Gln Ala Arg Gly Thr Pro Leu Leu Ala Arg Pro Ala 
            20                  25                  30


Pro Pro Gly Ala Ser Arg Tyr Ser Leu Tyr Thr Thr Gly Trp Arg Pro 
        35                  40                  45


Arg Leu Arg Pro Gly Pro His Lys Ala Leu Cys Ala Tyr Val Val His 
    50                  55                  60


Arg Asn Val Thr Cys Ile Leu Gln Glu Gly Ala Glu Ser Tyr Val Lys 
65                  70                  75                  80


Ala Glu Tyr Arg Gln Cys Arg Trp Gly Pro Lys Cys Pro Gly Thr Val 
                85                  90                  95


Thr Tyr Arg Thr Val Leu Arg Pro Lys Tyr Lys Val Gly Pro Ala Gly 
            100                 105                 110


Gly Val Arg Gly Pro Thr Ala Ala Pro Thr Leu Gly Glu Pro Ala Gly 
        115                 120                 125


Trp Leu 
    130


<210>  10163
<211>  3827
<212>  DNA
<213>  Homo sapiens

<400>  10163
cgcctcccct ccgcggcccc agccgctagc agcgccggcc actccgcggg acgcagccgc     60

cgcgaagcgc caggcggccg ggccagcgag ctcgggggcc gaaggggacc ccgggaccct    120

cggggcggga cccgggccga ccagcggcgg gggcggcgcg gcgctgcagg cggacacccg    180

gcggggggca ccgcgcgggg ccgggcagag gcgcgggggc cgctatgggc cgccgccgcc    240

tgctcgtctg gctgtgcgcc gtcgcggcgc tgctctcggg ggcgcaggcc aggggcaccc    300

cgctcctggc gcggcctgcg ccgcccggtg cctcccgcta cagtctctac acgacgggat    360

ggcgcccgcg gctgcgcccg gggccgcaca aggccctctg tgcctatgtg gtgcacagga    420

atgtgacctg catcctacag gagggagcgg agagctacgt aaaggctgaa taccggcagt    480

gtagatgggg gcccaagtgc cccgggacag tcacgtaccg cacagtactc agacccaaat    540

acaaggttgg ctacaagaca gtgacagacc tcgcctggcg ttgctgtccc ggcttcactg    600

ggaaacgctg ccctgagcac ctcacggacc atggggctgc ctcaccccag ctggagcctg    660

agcctcagat tccttcaggg cagctggacc caggccccag gcccccttcc tacagcagag    720

cagcccccag ccctcatgga aggaaaggcc cagggctgtt tggtgagcgg ctggaacgcc    780

tggagggtga tgtccagcgc ctggctcaaa catatggtac cctcagtggc ctggtggcta    840

gccacgagga tcccaacagg atgactggtg gccccagggc tcctgctgtc cctgtgggct    900

ttggggtcat ccctgagggg cttgtgggcc caggagacag agccagaggg ccactaacac    960

ctcccttaga cgagatccta agcaaggtga cagaggtgag caacactctt cagaccaagg   1020

tgcagcttct agacaaggtg catgggctgg cacttggcca tgaggcccac ctgcagcggc   1080

tgcgggaagc cccaccatcc ccgctcacct ccctggccct gctggaggag tacgtggacc   1140

gacggctgca ccgactctgg gggagcctgc tggatggctt tgagcagaag ctgcaaggcg   1200

tccagagtga gtgtgacctg cgggtgcagg aggtacggcg gcaatgtgag gagggtcagg   1260

ccgccagccg gaggctgcac cagagccttg atggccggga gctggccctg cgccaggagc   1320

tgtcacagct gggcagccag ctgcagggcc tgagcgtgtc tggcaggggc agctgctgtg   1380

ggcaactagc cttgatcaat gcccgtatgg atggccttga gagggccctg caggcagtca   1440

ccgagaccca aaggggcccc ggtgccccgg ccggggatga gcttacgagg ctctctgctg   1500

ccatgctcga gggaggtgtg gacgggctgc ttgagggtct ggagacgctc aatgggacag   1560

agggtggagc aaggggatgc tgtctgaggt tggacatggg ggggtgggga gtgggcggct   1620

ttgggaccat gctggaagag cgcgtgcaga gcctcgagga gcgcctagca acattggctg   1680

gggagctaag ccatgacagc gcctctccgg gcaggtcagc tcggcccctt gtacagacag   1740

agctggctgt gctagagcaa cggttggtct cactggagac ttcgtgcacc ccgagcacca   1800

cctcagccat cctggacagc ctcgtggcag aggtgaaggc ctggcagagc cggagcgagg   1860

ccctcctacg ccaggtggcc agccacgcag cactgctcca gcagctcaat ggcactgtgg   1920

ccgaggtcca gggacagctg gcagaaggga cgggcagctc acttcaaggc gagatcactc   1980

tgctcaaggt caatctgaac tcagtgagca agtcgctcac aggcctcagt gactctgtca   2040

gccagtactc tgatgccttc ttggctgcca acacgtccct ggatgagcgg gaacgcaagg   2100

tggaagccga agtccaggcc atccaggagc aggtcagcag ccaaggctcc aggcttcagg   2160

ctggccacag gcaggtcctg aacctgcgtg gggagctgga gcaactcaag gctggtgtgg   2220

ccaaggtggc cagtgggctg agccgctgcc aggacacagc ccagaaactt cagcacacag   2280

tgggacactt tgaccagcgg gtggcacaag tggagggtgc gtgcaggagg ctgggcctgc   2340

tggccgcggg cctggacagc ttgcccactg agccactgag gcccagagag ggcctgtgga   2400

gccatgtgga ccagctgaat cgtacgctgg cccagcacac gcaggacatt gcccgcctcc   2460

gggatgacct actggactgc caggcccagc tggctgagca ggtgcggcca gggcaagcca   2520

actagacagg ctggccagga cccaacccct agatcccacc aactcgggga acatcacccc   2580

agagcccagc cttatccagc agcgccttcc agccttccct ggctagccca aatggcacta   2640

aggaggccac tgagggaatc ctccacgtgg ctgtcccagc caccaaaacc catgcacagt   2700

gctgcagaaa ctggacagtt ccggacagcg gtcaaggcaa ggatgtcatg cttgaaggcc   2760

agggtagact tgagagagtt cacattccac tgtcagcaaa tcagtgtctg gacagccagc   2820

tgcagggcct gagcatggct ggcaggggca gctgctgtgg caaactggcc ttgatcagtg   2880

tccgtatgta aggccttgag aggaccctgc aggcagtcag caccagcctc agcaactgtg   2940

cagagaccta caggcccaca gccagtggcc tgtccgcatt gccctgtgcc cacaagcaac   3000

agtccacagc ccttggtggc ttctgttcct tgtcccctcg gcttctcttc gcagccatca   3060

ggactaggtt tgtgcaggaa ggtgatgccc actggaactc tcctcacacc tggcagcttc   3120

atggatgttg tatctgaact aaggaccaga ggctgccaga tgtttctggc tcctcacgtg   3180

tccttcagga cagaacagaa gcacaaagac tcagccaaga gttctcttta ttccctttga   3240

tcctccccca aggtgagggc ttaggcagct gtagaacccc aggaaagaac ggaatccagg   3300

caatctgttt agagaccccc cactccaaat ttatcctttt cctttccttc ccctaagatg   3360

tttccagggc cctctggtgc ccacactgtc ctcttccttc cacttggggg tggggaaatc   3420

cttcctgcga ggtcagggca tttctctaca aagtggcctg aatgaggcca ggccctgaga   3480

aggagccacc agctggagga aaggggctcc aagccttgct tttaacaccc ctgcaaaacc   3540

cccaccctcc caagatgttc acaaaaggtg agaaattcag gtacgaaacc atcaatggac   3600

aacttgaaaa tgcatgttcc tcaggcctat gcagttccca gagactcttg acaccggtct   3660

ctgctgaggc tcccagcctc agtttccccc acagcagcac gggccccact gtgctgctct   3720

tcaggtcccc acagccctgc ctttggttcc tggacatttg gtattctgcc ctccactctg   3780

gtactatcag agtagggcag gctctggatt aaagctttta gccggtc                 3827


<210>  10164
<211>  766
<212>  PRT
<213>  Homo sapiens

<400>  10164

Met Gly Arg Arg Arg Leu Leu Val Trp Leu Cys Ala Val Ala Ala Leu 
1               5                   10                  15


Leu Ser Gly Ala Gln Ala Arg Gly Thr Pro Leu Leu Ala Arg Pro Ala 
            20                  25                  30


Pro Pro Gly Ala Ser Arg Tyr Ser Leu Tyr Thr Thr Gly Trp Arg Pro 
        35                  40                  45


Arg Leu Arg Pro Gly Pro His Lys Ala Leu Cys Ala Tyr Val Val His 
    50                  55                  60


Arg Asn Val Thr Cys Ile Leu Gln Glu Gly Ala Glu Ser Tyr Val Lys 
65                  70                  75                  80


Ala Glu Tyr Arg Gln Cys Arg Trp Gly Pro Lys Cys Pro Gly Thr Val 
                85                  90                  95


Thr Tyr Arg Thr Val Leu Arg Pro Lys Tyr Lys Val Gly Tyr Lys Thr 
            100                 105                 110


Val Thr Asp Leu Ala Trp Arg Cys Cys Pro Gly Phe Thr Gly Lys Arg 
        115                 120                 125


Cys Pro Glu His Leu Thr Asp His Gly Ala Ala Ser Pro Gln Leu Glu 
    130                 135                 140


Pro Glu Pro Gln Ile Pro Ser Gly Gln Leu Asp Pro Gly Pro Arg Pro 
145                 150                 155                 160


Pro Ser Tyr Ser Arg Ala Ala Pro Ser Pro His Gly Arg Lys Gly Pro 
                165                 170                 175


Gly Leu Phe Gly Glu Arg Leu Glu Arg Leu Glu Gly Asp Val Gln Arg 
            180                 185                 190


Leu Ala Gln Thr Tyr Gly Thr Leu Ser Gly Leu Val Ala Ser His Glu 
        195                 200                 205


Asp Pro Asn Arg Met Thr Gly Gly Pro Arg Ala Pro Ala Val Pro Val 
    210                 215                 220


Gly Phe Gly Val Ile Pro Glu Gly Leu Val Gly Pro Gly Asp Arg Ala 
225                 230                 235                 240


Arg Gly Pro Leu Thr Pro Pro Leu Asp Glu Ile Leu Ser Lys Val Thr 
                245                 250                 255


Glu Val Ser Asn Thr Leu Gln Thr Lys Val Gln Leu Leu Asp Lys Val 
            260                 265                 270


His Gly Leu Ala Leu Gly His Glu Ala His Leu Gln Arg Leu Arg Glu 
        275                 280                 285


Ala Pro Pro Ser Pro Leu Thr Ser Leu Ala Leu Leu Glu Glu Tyr Val 
    290                 295                 300


Asp Arg Arg Leu His Arg Leu Trp Gly Ser Leu Leu Asp Gly Phe Glu 
305                 310                 315                 320


Gln Lys Leu Gln Gly Val Gln Ser Glu Cys Asp Leu Arg Val Gln Glu 
                325                 330                 335


Val Arg Arg Gln Cys Glu Glu Gly Gln Ala Ala Ser Arg Arg Leu His 
            340                 345                 350


Gln Ser Leu Asp Gly Arg Glu Leu Ala Leu Arg Gln Glu Leu Ser Gln 
        355                 360                 365


Leu Gly Ser Gln Leu Gln Gly Leu Ser Val Ser Gly Arg Gly Ser Cys 
    370                 375                 380


Cys Gly Gln Leu Ala Leu Ile Asn Ala Arg Met Asp Gly Leu Glu Arg 
385                 390                 395                 400


Ala Leu Gln Ala Val Thr Glu Thr Gln Arg Gly Pro Gly Ala Pro Ala 
                405                 410                 415


Gly Asp Glu Leu Thr Arg Leu Ser Ala Ala Met Leu Glu Gly Gly Val 
            420                 425                 430


Asp Gly Leu Leu Glu Gly Leu Glu Thr Leu Asn Gly Thr Glu Gly Gly 
        435                 440                 445


Ala Arg Gly Cys Cys Leu Arg Leu Asp Met Gly Gly Trp Gly Val Gly 
    450                 455                 460


Gly Phe Gly Thr Met Leu Glu Glu Arg Val Gln Ser Leu Glu Glu Arg 
465                 470                 475                 480


Leu Ala Thr Leu Ala Gly Glu Leu Ser His Asp Ser Ala Ser Pro Gly 
                485                 490                 495


Arg Ser Ala Arg Pro Leu Val Gln Thr Glu Leu Ala Val Leu Glu Gln 
            500                 505                 510


Arg Leu Val Ser Leu Glu Thr Ser Cys Thr Pro Ser Thr Thr Ser Ala 
        515                 520                 525


Ile Leu Asp Ser Leu Val Ala Glu Val Lys Ala Trp Gln Ser Arg Ser 
    530                 535                 540


Glu Ala Leu Leu Arg Gln Val Ala Ser His Ala Ala Leu Leu Gln Gln 
545                 550                 555                 560


Leu Asn Gly Thr Val Ala Glu Val Gln Gly Gln Leu Ala Glu Gly Thr 
                565                 570                 575


Gly Ser Ser Leu Gln Gly Glu Ile Thr Leu Leu Lys Val Asn Leu Asn 
            580                 585                 590


Ser Val Ser Lys Ser Leu Thr Gly Leu Ser Asp Ser Val Ser Gln Tyr 
        595                 600                 605


Ser Asp Ala Phe Leu Ala Ala Asn Thr Ser Leu Asp Glu Arg Glu Arg 
    610                 615                 620


Lys Val Glu Ala Glu Val Gln Ala Ile Gln Glu Gln Val Ser Ser Gln 
625                 630                 635                 640


Gly Ser Arg Leu Gln Ala Gly His Arg Gln Val Leu Asn Leu Arg Gly 
                645                 650                 655


Glu Leu Glu Gln Leu Lys Ala Gly Val Ala Lys Val Ala Ser Gly Leu 
            660                 665                 670


Ser Arg Cys Gln Asp Thr Ala Gln Lys Leu Gln His Thr Val Gly His 
        675                 680                 685


Phe Asp Gln Arg Val Ala Gln Val Glu Gly Ala Cys Arg Arg Leu Gly 
    690                 695                 700


Leu Leu Ala Ala Gly Leu Asp Ser Leu Pro Thr Glu Pro Leu Arg Pro 
705                 710                 715                 720


Arg Glu Gly Leu Trp Ser His Val Asp Gln Leu Asn Arg Thr Leu Ala 
                725                 730                 735


Gln His Thr Gln Asp Ile Ala Arg Leu Arg Asp Asp Leu Leu Asp Cys 
            740                 745                 750


Gln Ala Gln Leu Ala Glu Gln Val Arg Pro Gly Gln Ala Asn 
        755                 760                 765


<210>  10165
<211>  840
<212>  DNA
<213>  Homo sapiens

<400>  10165
ttactctagt cgtcatcttg gtgagaatct agaatacctg ggggggcagc atcttatagc     60

actctgtatc ttacacttat cacttccctc cacccccacc tcctttaaaa aaaaaacaaa    120

attactacag aaatctgata ttctaaggag aaggcatttg ggcattttta tttcttctgt    180

tttatttttg taaggaatgg gacaacaacc agatccagcc tttggtcgag tgtctagtcc    240

tcccaatgca atgatgtcgt caagaatggg tccctcccag aatcccatga tgcaacaccc    300

gcaggctgca tccatctatc agtcctcaga aatgaagggc tggccatcag gaaatttggc    360

caggaacagc tccttttccc agcagcagtt tgcccaccag gggaatcctg cagtgtatag    420

tatggtgcac atgaatggca gcagtggtca catgggacag atgaacatga accccatgcc    480

catgtctggc atgcctatgg gtcctgatca gaaatactgc tgacatctct gcaccaggac    540

ctcttaagga aaccactgta caaatgacac tgcactagga ttattgggaa ggaatcattg    600

ttccaggcat ccatcttgga agaaaggacc agctttgagc tccatcaagg gtattttaag    660

tgatgtcatt tgagcaggac tggattttaa gccgaagggc aatatctacg tgtttttccc    720

ccctccttct gctgtgtatc atggtgttca aaacagaaat gttttttggc attccacctc    780

ctagggatat aattctggag acatggagtg ttactgatca taaaactttt gtgtcacttt    840


<210>  10166
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  10166

Met Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro 
1               5                   10                  15


Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met Met 
            20                  25                  30


Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly 
        35                  40                  45


Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln 
    50                  55                  60


Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn 
65                  70                  75                  80


Gly Ser Ser Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met 
                85                  90                  95


Ser Gly Met Pro Met Gly Pro Asp Gln Lys Tyr Cys 
            100                 105


<210>  10167
<211>  3982
<212>  DNA
<213>  Homo sapiens

<400>  10167
ttactctagt cgtcatcttg gtgagaatct agaatacctg ggggggcagc atcttatagc     60

actctgtatc ttacacttat cacttccctc cacccccacc tcctttaaaa aaaaaacaaa    120

attactacag aaatctgata ttctaaggag aaggcatttg ggcattttta tttcttctgt    180

tttatttttg taaggaatgg gacaacaacc agatccagcc tttggtcgag tgtctagtcc    240

tcccaatgca atgatgtcgt caagaatggg tccctcccag aatcccatga tgcaacaccc    300

gcaggctgca tccatctatc agtcctcaga aatgaagggc tggccatcag gaaatttggc    360

caggaacagc tccttttccc agcagcagtt tgcccaccag gggaatcctg cagtgtatag    420

tatggtgcac atgaatggca gcagtggtca catgggacag atgaacatga accccatgcc    480

catgtctggc atgcctatgg gtcctgatca gaaatactgc tgacatctct gcaccaggac    540

ctcttaagga aaccactgta caaatgacac tgcactagga ttattgggaa ggaatcattg    600

ttccaggcat ccatcttgga agaaaggacc agctttgagc tccatcaagg gtattttaag    660

tgatgtcatt tgagcaggac tggattttaa gccgaagggc aatatctacg tgtttttccc    720

ccctccttct gctgtgtatc atggtgttca aaacagaaat gttttttggc attccacctc    780

ctagggatat aattctggag acatggagtg ttactgatca taaaactttt gtgtcacttt    840

tttctgcctt gctagccaaa atctcttaaa tacacgtagg tgggccagag aacattggaa    900

gaatcaagag agattagaat atctggtttc tctagttgca gtattggaca aagagcatag    960

tcccagcctt caggtgtagt agttctgtgt tgaccctttg tccagtggaa ttggtgattc   1020

tgaattgtcc tttactaatg gtgttgagtt gctctgtccc tattatttgc cctaggcttt   1080

ctcctaatga aggttttcat ttgccattca tgtcctgtaa tacttcacct ccaggaactg   1140

tcatggatgt ccaaatggct ttgcagaaag gaaatgagat gacagtattt aatcgcagca   1200

gtagcaaact tttcacatgc taatgtgcag ctgagtgcac tttatttaaa aagaatggat   1260

aaatgcaata ttcttgaggt cttgagggaa tagtgaaaca cattcctggt ttttgcctac   1320

acttacgtgt tagacaagaa ctatgatttt tttttttaaa gtactggtgt caccctttgc   1380

ctatatggta gagcaataat gctttttaaa aataaacttc tgaaaaccca aggccaggta   1440

ctgcattctg aatcagaatc tcgcagtgtt tctgtgaata gatttttttg taaatatgac   1500

ctttaagata ttgtattatg taaaatatgt atataccttt ttttgtaggt cacaacaact   1560

catttttaca gagtttgtga agctaaatat ttaacattgt tgatttcagt aagctgtgtg   1620

gtgaggctac cagtggaaga gacatccctt gacttttgtg gcctggggga ggggtagtgc   1680

tccacagctt ttccttcccc accccccagc cttagatgcc tcgctctttt caatctctta   1740

atctaaatgc tttttaaaga gattatttgt ttagatgtag gcattttaat tttttaaaaa   1800

ttcctctacc agaactaagc actttgttaa tttgggggga aagaatagat atggggaaat   1860

aaacttaaaa aaaaatcagg aatttaaaaa aacgagcaat ttgaagagaa tcttttggat   1920

tttaagcagt ccgaaataat agcaattcat gggctgtgtg tgtgtgtgta tgtgtgtgtg   1980

tgtgtgtgta tgtttaatta tgttaccttt tcatcccctt taggagcgtt ttcagatttt   2040

ggttgctaag acctgaatcc catattgaga tctcgagtag aatccttggt gtggtttctg   2100

gtgtctgctc agctgtcccc tcattctact aatgtgatgc tttcattatg tccctgtgga   2160

ttagaatagt gtcagttatt tcttaagtaa ctcagtaccc agaacagcca gttttactgt   2220

gattcagagc cacagtctaa ctgagcacct tttaaacccc tccctcttct gccccctacc   2280

acttttctgc tgttgcctct ctttgacacc tgttttagtc agttgggagg aagggaaaaa   2340

tcaagtttaa ttccctttat ctgggttaat tcatttggtt caaatagttg acggaattgg   2400

gtttctgaat gtctgtgaat ttcagaggtc tctgctagcc ttggtatcat tttctagcaa   2460

taactgagag ccagttaatt ttaagaattt cacacattta gccaatcttt ctagatgtct   2520

ctgaaggtaa gatcatttaa tatctttgat atgcttacga gtaagtgaat cctgattatt   2580

tccagaccca ccaccagagt ggatcttatt ttcaaagcag tatagacaat tatgagtttg   2640

ccctctttcc cctaccaagt tcaaaatata tctaagaaag attgtaaatc cgaaaacttc   2700

cattgtagtg gcctgtgctt ttcagatagt atactctcct gtttggagac agaggaagaa   2760

ccaggtcagt ctgtctcttt ttcagctcaa ttgtatctga cccttcttta agttatgtgt   2820

gtggggagaa atagaatggt gctcttatct ttcttgactt taaaaaaatt attaaaaaca   2880

aaaaaaaaat aaattttttt gcaatccttt cctcagacct ggctccaggc taactggaag   2940

gcagcactcc cttttttata tagtagaaaa atgaagttta ttataagttt ttatattttc   3000

tacttgttca tttggtgcaa actcaagatt tcttttaata ggtgcagtct ttgagataat   3060

ttgtttttac ctgtattgcc ctttatcttt tttaggtaat tctttgtact cctgctgtct   3120

acctctcctc acaccccagc accccccatt ttttcaaacc ttggtatctg ttgggtgaac   3180

agtataatct tttcatctgc ttttagaatg tgggatattt ccagtaccta cttttttttt   3240

ttttttttgc tgaatccaaa gatatataaa taaaatatat atattttata aagatcagaa   3300

tgatataaag gagatacatg tttcttcctt taaaaaataa acggaagtta cattgttaat   3360

gttcatatta tgatgccact tttctaaact gcatctggat tgaaaggtgt aaatatcaat   3420

aacagtgcta cttagttatc agtatttaat atctgaggtg agttgggggt atctatatta   3480

ggggtagggt attacagaag ataattggct tgatgtccta gaagttcttt gatccagagg   3540

tgggtgcagc tgaaagtaaa cagaatggat tgccagttac atgtatgcct gcccagttcc   3600

ctttttattt gcagaagctg tgagttttgt tcacaattag gttcctagga gcaaaacctc   3660

aaggattgat ttattgtttt caactccaag gcacactgtt aataaacgag cagggtgttt   3720

tctctcttcc tttctaatat atggagtttc gaagaataaa atatgagagc aatatttaaa   3780

ttctcaggaa ttgacttata ctcttgagaa tgaattcagt ttcaatcaag tttacattat   3840

gttgcttaaa aaaatagaaa ttattcttta tcttgcaaag aattgaaacc acatgaaatg   3900

acttatgggg gatggtgagc tgtgactgct ttgctgacca ttttggatgt cattgtaaat   3960

aaaggtttct atttaaaatt gg                                            3982


<210>  10168
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  10168

Met Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro 
1               5                   10                  15


Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met Met 
            20                  25                  30


Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly 
        35                  40                  45


Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln 
    50                  55                  60


Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn 
65                  70                  75                  80


Gly Ser Ser Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met 
                85                  90                  95


Ser Gly Met Pro Met Gly Pro Asp Gln Lys Tyr Cys 
            100                 105


<210>  10169
<211>  4045
<212>  DNA
<213>  Homo sapiens

<400>  10169
ttactctagt cgtcatcttg gtgagaatct agaatacctg ggggggcagc atcttatagc     60

actctgtatc ttacacttat cacttccctc cacccccacc tcctttaaaa aaaaaacaaa    120

attactacag aaatctgata ttctaaggag aaggcatttg ggcattttta tttcttctgt    180

tttatttttg taaggaatgg gacaacaacc agatccagcc tttggtcgag tgtctagtcc    240

tcccaatgca atgatgtcgt caagaatggg tccctcccag aatcccatga tgcaacaccc    300

gcaggctgca tccatctatc agtcctcaga aatgaagggc tggccatcag gaaatttggc    360

caggaacagc tccttttccc agcagcagtt tgcccaccag gggaatcctg cagtgtatag    420

tatggtgcac atgaatggca gcagtggtca catgggacag atgaacatga accccatgcc    480

catgtctggc atgcctatgg gtcctgatca gaaatactgc tgacatctct gcaccaggac    540

ctcttaagga aaccactgta caaatgacac tgcactagga ttattgggaa ggaatcattg    600

ttccaggcat ccatcttgga agaaaggacc agctttgagc tccatcaagg gtattttaag    660

tgatgtcatt tgagcaggac tggattttaa gccgaagggc aatatctacg tgtttttccc    720

ccctccttct gctgtgtatc atggtgttca aaacagaaat gttttttggc attccacctc    780

ctagggatat aattctggag acatggagtg ttactgatca taaaactttt gtgtcacttt    840

tttctgcctt gctagccaaa atctcttaaa tacacgtagg tgggccagag aacattggaa    900

gaatcaagag agattagaat atctggtttc tctagttgca gtattggaca aagagcatag    960

tcccagcctt caggtgtagt agttctgtgt tgaccctttg tccagtggaa ttggtgattc   1020

tgaattgtcc tttactaatg gtgttgagtt gctctgtccc tattatttgc cctaggcttt   1080

ctcctaatga aggttttcat ttgccattca tgtcctgtaa tacttcacct ccaggaactg   1140

tcatggatgt ccaaatggct ttgcagaaag gaaatgagat gacagtattt aatcgcagca   1200

gtagcaaact tttcacatgc taatgtgcag ctgagtgcac tttatttaaa aagaatggat   1260

aaatgcaata ttcttgaggt cttgagggaa tagtgaaaca cattcctggt ttttgcctac   1320

acttacgtgt tagacaagaa ctatgatttt tttttttaaa gtactggtgt caccctttgc   1380

ctatatggta gagcaataat gctttttaaa aataaacttc tgaaaaccca aggccaggta   1440

ctgcattctg aatcagaatc tcgcagtgtt tctgtgaata gatttttttg taaatatgac   1500

ctttaagata ttgtattatg taaaatatgt atataccttt ttttgtaggt cacaacaact   1560

catttttaca gagtttgtga agctaaatat ttaacattgt tgatttcagt aagctgtgtg   1620

gtgaggctac cagtggaaga gacatccctt gacttttgtg gcctggggga ggggtagtgc   1680

tccacagctt ttccttcccc accccccagc cttagatgcc tcgctctttt caatctctta   1740

atctaaatgc tttttaaaga gattatttgt ttagatgtag gcattttaat tttttaaaaa   1800

ttcctctacc agaactaagc actttgttaa tttgggggga aagaatagat atggggaaat   1860

aaacttaaaa aaaaatcagg aatttaaaaa aacgagcaat ttgaagagaa tcttttggat   1920

tttaagcagt ccgaaataat agcaattcat gggctgtgtg tgtgtgtgta tgtgtgtgtg   1980

tgtgtgtgta tgtttaatta tgttaccttt tcatcccctt taggagcgtt ttcagatttt   2040

ggttgctaag acctgaatcc catattgaga tctcgagtag aatccttggt gtggtttctg   2100

gtgtctgctc agctgtcccc tcattctact aatgtgatgc tttcattatg tccctgtgga   2160

ttagaatagt gtcagttatt tcttaagtaa ctcagtaccc agaacagcca gttttactgt   2220

gattcagagc cacagtctaa ctgagcacct tttaaacccc tccctcttct gccccctacc   2280

acttttctgc tgttgcctct ctttgacacc tgttttagtc agttgggagg aagggaaaaa   2340

tcaagtttaa ttccctttat ctgggttaat tcatttggtt caaatagttg acggaattgg   2400

gtttctgaat gtctgtgaat ttcagaggtc tctgctagcc ttggtatcat tttctagcaa   2460

taactgagag ccagttaatt ttaagaattt cacacattta gccaatcttt ctagatgtct   2520

ctgaaggtaa gatcatttaa tatctttgat atgcttacga gtaagtgaat cctgattatt   2580

tccagaccca ccaccagagt ggatcttatt ttcaaagcag tatagacaat tatgagtttg   2640

ccctctttcc cctaccaagt tcaaaatata tctaagaaag attgtaaatc cgaaaacttc   2700

cattgtagtg gcctgtgctt ttcagatagt atactctcct gtttggagac agaggaagaa   2760

ccaggtcagt ctgtctcttt ttcagctcaa ttgtatctga cccttcttta agttatgtgt   2820

gtggggagaa atagaatggt gctcttatct ttcttgactt taaaaaaatt attaaaaaca   2880

aaaaaaaaat aaattttttt gcaatccttt cctcagacct ggctccaggc taactggaag   2940

gcagcactcc cttttttata tagtagaaaa atgaagttta ttataagttt ttatattttc   3000

tacttgttca tttggtgcaa actcaagatt tcttttaata ggtgcagtct ttgagataat   3060

ttgtttttac ctgtattgcc ctttatcttt tttaggtaat tctttgtact cctgctgtct   3120

acctctcctc acaccccagc accccccatt ttttcaaacc ttggtatctg ttgggtgaac   3180

agtataatct tttcatctgc ttttagaatg tgggatattt ccagtaccta cttttttttt   3240

ttttttttgc tgaatccaaa gatatataaa taaaatatat atattttata aagatcagaa   3300

tgatataaag gagatacatg tttcttcctt taaaaaataa acggaagtta cattgttaat   3360

gttcatatta tgatgccact tttctaaact gcatctggat tgaaaggtgt aaatatcaat   3420

aacagtgcta cttagttatc agtatttaat atctgaggtg agttgggggt atctatatta   3480

ggggtagggt attacagaag ataattggct tgatgtccta gaagttcttt gatccagagg   3540

tgggtgcagc tgaaagtaaa cagaatggat tgccagttac atgtatgcct gcccagttcc   3600

ctttttattt gcagaagctg tgagttttgt tcacaattag gttcctagga gcaaaacctc   3660

aaggattgat ttattgtttt caactccaag gcacactgtt aataaacgag cagggtgttt   3720

tctctcttcc tttctaatat atggagtttc gaagaataaa atatgagagc aatatttaaa   3780

ttctcaggaa ttgacttata ctcttgagaa tgaattcagt ttcaatcaag tttacattat   3840

gttgcttaaa aaaatagaaa ttattcttta tcttgcaaag aattgaaacc acatgaaatg   3900

acttatgggg gatggtgagc tgtgactgct ttgctgacca ttttggatgt cattgtaaat   3960

aaaggtttct atttaaaatt ggagcctaaa gagttttttt tttttttttt tttttttaaa   4020

tccctgttgg gttaagggta aagga                                         4045


<210>  10170
<211>  108
<212>  PRT
<213>  Homo sapiens

<400>  10170

Met Gly Gln Gln Pro Asp Pro Ala Phe Gly Arg Val Ser Ser Pro Pro 
1               5                   10                  15


Asn Ala Met Met Ser Ser Arg Met Gly Pro Ser Gln Asn Pro Met Met 
            20                  25                  30


Gln His Pro Gln Ala Ala Ser Ile Tyr Gln Ser Ser Glu Met Lys Gly 
        35                  40                  45


Trp Pro Ser Gly Asn Leu Ala Arg Asn Ser Ser Phe Ser Gln Gln Gln 
    50                  55                  60


Phe Ala His Gln Gly Asn Pro Ala Val Tyr Ser Met Val His Met Asn 
65                  70                  75                  80


Gly Ser Ser Gly His Met Gly Gln Met Asn Met Asn Pro Met Pro Met 
                85                  90                  95


Ser Gly Met Pro Met Gly Pro Asp Gln Lys Tyr Cys 
            100                 105


<210>  10171
<211>  2397
<212>  DNA
<213>  Homo sapiens

<400>  10171
atggtgttca aaacagaaat gttttttggc attccacctc ctagggatat aattctggag     60

acatggagtg ttactgatca taaaactttt gtgtcacttt tttctgcctt gctagccaaa    120

atctcttaaa tacacgtagg tgggccagag aacattggaa gaatcaagag agattagaat    180

atctggtttc tctagttgca gtattggaca aagagcatag tcccagcctt caggtgtagt    240

agttctgtgt tgaccctttg tccagtggaa ttggtgattc tgaattgtcc tttactaatg    300

gtgttgagtt gctctgtccc tattatttgc cctaggcttt ctcctaatga aggttttcat    360

ttgccattca tgtcctgtaa tacttcacct ccaggaactg tcatggatgt ccaaatggct    420

ttgcagaaag gaaatgagat gacagtattt aatcgcagca gtagcaaact tttcacatgc    480

taatgtgcag ctgagtgcac tttatttaaa aagaatggat aaatgcaata ttcttgaggt    540

cttgagggaa tagtgaaaca cattcctggt ttttgcctac acttacgtgt tagacaagaa    600

ctatgatttt tttttttaaa gtactggtgt caccctttgc ctatatggta gagcaataat    660

gctttttaaa aataaacttc tgaaaaccca aggccaggta ctgcattctg aatcagaatc    720

tcgcagtgtt tctgtgaata gatttttttg taaatatgac ctttaagata ttgtattatg    780

taaaatatgt atataccttt ttttgtaggt cacaacaact catttttaca gagtttgtga    840

agctaaatat ttaacattgt tgatttcagt aagctgtgtg gtgaggctac cagtggaaga    900

gacatccctt gacttttgtg gcctggggga ggggtagtgc tccacagctt ttccttcccc    960

accccccagc cttagatgcc tcgctctttt caatctctta atctaaatgc tttttaaaga   1020

gattatttgt ttagatgtag gcattttaat tttttaaaaa ttcctcctac caagttcaaa   1080

atatatctaa gaaagattgt aaatccgaaa acttccattg tagtggcctg tgcttttcag   1140

atagtatact ctcctgtttg gagacagagg aagaaccagg tcagtctgtc tctttttcag   1200

ctcaattgta tctgaccctt ctttaagtta tgtgtgtggg gagaaataga atggtgctct   1260

tatctttctt gactttaaaa aaattattaa aaacaaaaaa aaaataaatt tttttgcaat   1320

cctttcctca gacctggctc caggctaact ggaaggcagc actccctttt ttatatagta   1380

gaaaaatgaa gtttattata agtttttata ttttctactt gttcatttgg tgcaaactca   1440

agatttcttt taataggtgc agtctttgag ataatttgtt tttacctgta ttgcccttta   1500

tcttttttag gtaattcttt gtactcctgc tgtctacctc tcctcacacc ccagcacccc   1560

ccattttttc aaaccttggt atctgttggg tgaacagtat aatcttttca tctgctttta   1620

gaatgtggga tatttccagt acctactttt tttttttttt tttgctgaat ccaaagatat   1680

ataaataaaa tatatatatt ttataaagat cagaatgata taaaggagat acatgtttct   1740

tcctttaaaa aataaacgga agttacattg ttaatgttca tattatgatg ccacttttct   1800

aaactgcatc tggattgaaa ggtgtaaata tcaataacag tgctacttag ttatcagtat   1860

ttaatatctg aggtgagttg ggggtatcta tattaggggt agggtattac agaagataat   1920

tggcttgatg tcctagaagt tctttgatcc agaggtgggt gcagctgaaa gtaaacagaa   1980

tggattgcca gttacatgta tgcctgccca gttccctttt tatttgcaga agctgtgagt   2040

tttgttcaca attaggttcc taggagcaaa acctcaagga ttgatttatt gttttcaact   2100

ccaaggcaca ctgttaataa acgagcaggg tgttttctct cttcctttct aatatatgga   2160

gtttcgaaga ataaaatatg agagcaatat ttaaattctc aggaattgac ttatactctt   2220

gagaatgaat tcagtttcaa tcaagtttac attatgttgc ttaaaaaaat agaaattatt   2280

ctttatcttg caaagaattg aaaccacatg aaatgactta tgggggatgg tgagctgtga   2340

ctgctttgct gaccattttg gatgtcattg taaataaagg tttctattta aaattgg      2397


<210>  10172
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  10172

Met Val Leu Ser Cys Ser Val Pro Ile Ile Cys Pro Arg Leu Ser Pro 
1               5                   10                  15


Asn Glu Gly Phe His Leu Pro Phe Met Ser Cys Asn Thr Ser Pro Pro 
            20                  25                  30


Gly Thr Val Met Asp Val Gln Met Ala Leu Gln Lys Gly Asn Glu Met 
        35                  40                  45


Thr Val Phe Asn Arg Ser Ser Ser Lys Leu Phe Thr Cys 
    50                  55                  60


<210>  10173
<211>  2460
<212>  DNA
<213>  Homo sapiens

<400>  10173
atggtgttca aaacagaaat gttttttggc attccacctc ctagggatat aattctggag     60

acatggagtg ttactgatca taaaactttt gtgtcacttt tttctgcctt gctagccaaa    120

atctcttaaa tacacgtagg tgggccagag aacattggaa gaatcaagag agattagaat    180

atctggtttc tctagttgca gtattggaca aagagcatag tcccagcctt caggtgtagt    240

agttctgtgt tgaccctttg tccagtggaa ttggtgattc tgaattgtcc tttactaatg    300

gtgttgagtt gctctgtccc tattatttgc cctaggcttt ctcctaatga aggttttcat    360

ttgccattca tgtcctgtaa tacttcacct ccaggaactg tcatggatgt ccaaatggct    420

ttgcagaaag gaaatgagat gacagtattt aatcgcagca gtagcaaact tttcacatgc    480

taatgtgcag ctgagtgcac tttatttaaa aagaatggat aaatgcaata ttcttgaggt    540

cttgagggaa tagtgaaaca cattcctggt ttttgcctac acttacgtgt tagacaagaa    600

ctatgatttt tttttttaaa gtactggtgt caccctttgc ctatatggta gagcaataat    660

gctttttaaa aataaacttc tgaaaaccca aggccaggta ctgcattctg aatcagaatc    720

tcgcagtgtt tctgtgaata gatttttttg taaatatgac ctttaagata ttgtattatg    780

taaaatatgt atataccttt ttttgtaggt cacaacaact catttttaca gagtttgtga    840

agctaaatat ttaacattgt tgatttcagt aagctgtgtg gtgaggctac cagtggaaga    900

gacatccctt gacttttgtg gcctggggga ggggtagtgc tccacagctt ttccttcccc    960

accccccagc cttagatgcc tcgctctttt caatctctta atctaaatgc tttttaaaga   1020

gattatttgt ttagatgtag gcattttaat tttttaaaaa ttcctcctac caagttcaaa   1080

atatatctaa gaaagattgt aaatccgaaa acttccattg tagtggcctg tgcttttcag   1140

atagtatact ctcctgtttg gagacagagg aagaaccagg tcagtctgtc tctttttcag   1200

ctcaattgta tctgaccctt ctttaagtta tgtgtgtggg gagaaataga atggtgctct   1260

tatctttctt gactttaaaa aaattattaa aaacaaaaaa aaaataaatt tttttgcaat   1320

cctttcctca gacctggctc caggctaact ggaaggcagc actccctttt ttatatagta   1380

gaaaaatgaa gtttattata agtttttata ttttctactt gttcatttgg tgcaaactca   1440

agatttcttt taataggtgc agtctttgag ataatttgtt tttacctgta ttgcccttta   1500

tcttttttag gtaattcttt gtactcctgc tgtctacctc tcctcacacc ccagcacccc   1560

ccattttttc aaaccttggt atctgttggg tgaacagtat aatcttttca tctgctttta   1620

gaatgtggga tatttccagt acctactttt tttttttttt tttgctgaat ccaaagatat   1680

ataaataaaa tatatatatt ttataaagat cagaatgata taaaggagat acatgtttct   1740

tcctttaaaa aataaacgga agttacattg ttaatgttca tattatgatg ccacttttct   1800

aaactgcatc tggattgaaa ggtgtaaata tcaataacag tgctacttag ttatcagtat   1860

ttaatatctg aggtgagttg ggggtatcta tattaggggt agggtattac agaagataat   1920

tggcttgatg tcctagaagt tctttgatcc agaggtgggt gcagctgaaa gtaaacagaa   1980

tggattgcca gttacatgta tgcctgccca gttccctttt tatttgcaga agctgtgagt   2040

tttgttcaca attaggttcc taggagcaaa acctcaagga ttgatttatt gttttcaact   2100

ccaaggcaca ctgttaataa acgagcaggg tgttttctct cttcctttct aatatatgga   2160

gtttcgaaga ataaaatatg agagcaatat ttaaattctc aggaattgac ttatactctt   2220

gagaatgaat tcagtttcaa tcaagtttac attatgttgc ttaaaaaaat agaaattatt   2280

ctttatcttg caaagaattg aaaccacatg aaatgactta tgggggatgg tgagctgtga   2340

ctgctttgct gaccattttg gatgtcattg taaataaagg tttctattta aaattggagc   2400

ctaaagagtt tttttttttt tttttttttt ttaaatccct gttgggttaa gggtaaagga   2460


<210>  10174
<211>  61
<212>  PRT
<213>  Homo sapiens

<400>  10174

Met Val Leu Ser Cys Ser Val Pro Ile Ile Cys Pro Arg Leu Ser Pro 
1               5                   10                  15


Asn Glu Gly Phe His Leu Pro Phe Met Ser Cys Asn Thr Ser Pro Pro 
            20                  25                  30


Gly Thr Val Met Asp Val Gln Met Ala Leu Gln Lys Gly Asn Glu Met 
        35                  40                  45


Thr Val Phe Asn Arg Ser Ser Ser Lys Leu Phe Thr Cys 
    50                  55                  60


<210>  10175
<211>  3134
<212>  DNA
<213>  Homo sapiens

<400>  10175
ctttctgtcc tctggagcac agatgttcat gcctgcatct acctccctca ccataactaa     60

ggtcagcgct gaatgaagcc atcagggtcc tgaaactgat catggtgaca ctggatttta    120

ggcaatctac aaggctatct aggagactta gggcaggttc ccctcataat tcagtctacc    180

cctcataatt cagtctactc tgagtaggga acactatcag catcatggga ttgtgacaaa    240

aaagcataag atggttttct ggtgtgttgg ggttgttttg cctaaactat ctgctcctgt    300

tttgtttttc atttctcctt catttaggac ttaaagatgg aggaagctat gagcaataca    360

ggtatttcgt tttattatta aagcctaaac aaagttctcc tatcttggcc catccttcag    420

tctcatctct gtgagtctgc acctgttatc ttgagaaact gcccttccct ctggtctgcc    480

cgagaccagg atcacccacc aaagataggt gtcacctagg agaccttctt tgtatagttc    540

tttggggact ttttctttct tggtgatggt taacattcat tctcctttga cacttgaaaa    600

cttaggcagt ttcagcgtcg aaagtggcca gaaatgaaga gaccttcttc caaatcactg    660

ggacaactgt gggaaggctg ggaaggttaa gaaacaacag aggtggacct ccaaaaacat    720

agaggcatca cctgactgca caggcaatga aaaaccatgt gggtgatttc cagcagacct    780

gtggtattgg ccaggaggcc tgagaaagca agcacgcact ctcagtcaac atgacagatt    840

ctggaggata accagcagga gcagagataa cttcaggaag tccatttttg cccctgcttt    900

tgctttggat tatacctcac cagctgcaca aaatgcattt tttcgtatca aaaagtcacc    960

actaaccctc ccccagaagc tcacaaagga aaacggagag agcgagcgag agagatttcc   1020

ttggaaattt ctcccaaggg cgaaagtcat tggaattttt aaatcatagg ggaaaagcag   1080

tcctgttcta aatcctctta ttcttttggt ttgtcacaaa gaaggaacta agaagcagga   1140

cagaggcaac gtggagaggc tgaaaacagt gcagagacgt ttgacaatga gtcagtagca   1200

caaaagagat gacatttacc tagcactata aaccctggtt gcctctgaag aaactgcctt   1260

cattgtatat atgtgactat ttacatgtaa tcaacatggg aacttttagg ggaacctaat   1320

aagaaatccc aattttcagg agtggtggtg tcaataaacg ctctgtggcc agtgtaaaag   1380

aaaatccctc gcagttgtgg acatttctgt tcctgtccag ataccatttc tcctagtatt   1440

tctttgttat gtcccagaac tgatgttttt tttttaaggt actgaaaaga aatgaagttg   1500

atgtatgtcc caagttttga tgaaactgta tttgtaaaaa aaattttgta gtttaagtat   1560

tgtcatacag tgttcaaaac cccagccaat gaccagcagt tggtatgaag aacctttgac   1620

attttgtaaa aggccatttc ttgggagttt tttggtgtgt ctgttttttt aaagtattca   1680

agatactacc agtcaacatc tttttggaag aaaatgcctt gggtttagaa gattttctta   1740

aaaggggagt agatggttgt agattgacta aaaagtctac catacttcaa gggactacag   1800

gtaagtctca tagtatacca gctttggtac ttcatttttt aaaaaagtat taatcaattg   1860

caaagaaatt cgccttggcc aacccttctt tgtgtatcag gtagtctaac ctgatacaag   1920

tagttgacag atttcaacta tcaatcacca gtccaaccca tttctcattt aacagatgac   1980

ggagataatc cctaaaagca cccacatttg tttcaatgcc ccaaacaggc caaggctccc   2040

tagcaactcc ctagtggcgt tttttaactt ctcagaaact gttaccatta tttgaaatag   2100

gcttccttaa cctcctttac ccttaaccca acagggattt aaaaaaaaaa aaaaaaaaaa   2160

aaaactcttt aggctccaat tttaaataga aacctttatt tacaatgaca tccaaaatgg   2220

tcagcaaagc agtcacagct caccatcccc cataagtcat ttcatgtggt ttcaattctt   2280

tgcaagataa agaataattt ctattttttt aagcaacata atgtaaactt gattgaaact   2340

gaattcattc tcaagagtat aagtcaattc ctgagaattt aaatattgct ctcatatttt   2400

attcttcgaa actccatata ttagaaagga agagagaaaa caccctgctc gtttattaac   2460

agtgtgcctt ggagttgaaa acaataaatc aatccttgag gttttgctcc taggaaccta   2520

attgtgaaca aaactcacag cttctgcaaa taaaaaggga actgggcagg catacatgta   2580

actggcaatc cattctgttt actttcagct gcacccacct ctggatcaaa gaacttctag   2640

gacatcaagc caattatctt ctgtaatacc ctacccctaa tatagatacc cccaactcac   2700

ctcagatatt aaatactgat aactaagtag cactgttatt gatatttaca cctttcaatc   2760

cagatgcagt ttagaaaagt ggcatcataa tatgaacatt aacaatgtaa cttccgttta   2820

ttttttaaag gaagaaacat gtatctcctt tatatcattc tgatctttat aaaatatata   2880

tattttattt atatatcttt ggattcagca aaaaaaaaaa aaaaaagtag gtactggaaa   2940

tatcccacat tctaaaagca gatgaaaaga ttatactgtt cacccaacag ataccaaggt   3000

ttgaaaaaat ggggggtgct ggggtgtgag gagaggtaga cagcaggagt acaaagaatt   3060

acctaaaaaa gataaagggc aatacaggta aaaacaaatt atctcaaaga ctgcacctat   3120

taaaagaaat cttg                                                     3134


<210>  10176
<211>  39
<212>  PRT
<213>  Homo sapiens

<400>  10176

Met Thr Glu Ile Ile Pro Lys Ser Thr His Ile Cys Phe Asn Ala Pro 
1               5                   10                  15


Asn Arg Pro Arg Leu Pro Ser Asn Ser Leu Val Ala Phe Phe Asn Phe 
            20                  25                  30


Ser Glu Thr Val Thr Ile Ile 
        35


<210>  10177
<211>  5952
<212>  DNA
<213>  Homo sapiens

<400>  10177
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gagtgagtgt gcgtctgtgt    600

gtcccggcga gggtgcgcgc tcggcgccgg gagcgcggcc agccgagtcc ggaggcatcg    660

ggaggtcgag agccgccggg accccagctc tgcgttcact gccccgtccg gagctggact    720

tcggggccgg ggccggggcc gtgcgccggg gacaggcagg gccgggtcgc gggccgcgcg    780

tcccccaggc cggagatctg cgagtgaaga gggacgaggg aaaagaaaca aagccacaga    840

cgcaacttga gactcccgca tcccaaaaga agcaccagat cagcaaaaaa agaagatggg    900

ccccccgagc ctcgtgctgt gcttgctgtc cgcaactgtg ttctccctgc tgggtggaag    960

ctcggccttc ctgtcgcacc accgcctgaa aggcaggttt cagagggacc gcaggaacat   1020

ccgccccaac atcatcctgg tgctgacgga cgaccaggat gtggagctgg gttccatgca   1080

ggtgatgaac aagacccggc gcatcatgga gcagggcggg gcgcacttca tcaacgcctt   1140

cgtgaccaca cccatgtgct gcccctcacg ctcctccatc ctcactggca agtacgtcca   1200

caaccacaac acctacacca acaatgagaa ctgctcctcg ccctcctggc aggcacagca   1260

cgagagccgc acctttgccg tgtacctcaa tagcactggc taccggacag ctttcttcgg   1320

gaagtatctt aatgaataca acggctccta cgtgccaccc ggctggaagg agtgggtcgg   1380

actccttaaa aactcccgct tttataacta cacgctgtgt cggaacgggg tgaaagagaa   1440

gcacggctcc gactactcca aggattacct cacagacctc atcaccaatg acagcgtgag   1500

cttcttccgc acgtccaaga agatgtaccc gcacaggcca gtcctcatgg tcatcagcca   1560

tgcagccccc cacggccctg aggattcagc cccacaatat tcacgcctct tcccaaacgc   1620

atctcagcac atcacgccga gctacaacta cgcgcccaac ccggacaaac actggatcat   1680

gcgctacacg gggcccatga agcccatcca catggaattc accaacatgc tccagcggaa   1740

gcgcttgcag accctcatgt cggtggacga ctccatggag acgatttaca acatgctggt   1800

tgagacgggc gagctggaca acacgtacat cgtatacacc gccgaccacg gttaccacat   1860

cggccagttt ggcctggtga aagggaaatc catgccatat gagtttgaca tcagggtccc   1920

gttctacgtg aggggcccca acgtggaagc cggctgtctg aatccccaca tcgtcctcaa   1980

cattgacctg gcccccacca tcctggacat tgcaggcctg gacatacctg cggatatgga   2040

cgggaaatcc atcctcaagc tgctggacac ggagcggccg gtgaatcggt ttcacttgaa   2100

aaagaagatg agggtctggc gggactcctt cttggtggag agaggcaagc tgctacacaa   2160

gagagacaat gacaaggtgg acgcccagga ggagaacttt ctgcccaagt accagcgtgt   2220

gaaggacctg tgtcagcgtg ctgagtacca gacggcgtgt gagcagctgg gacagaagtg   2280

gcagtgtgtg gaggacgcca cggggaagct gaagctgcat aagtgcaagg gccccatgcg   2340

gctgggcggc agcagagccc tctccaacct cgtgcccaag tactacgggc agggcagcga   2400

ggcctgcacc tgtgacagcg gggactacaa gctcagcctg gccggacgcc ggaaaaaact   2460

cttcaagaag aagtacaagg ccagctatgt ccgcagtcgc tccatccgct cagtggccat   2520

cgaggtggac ggcagggtgt accacgtagg cctgggtgat gccgcccagc cccgaaacct   2580

caccaagcgg cactggccag gggcccctga ggaccaagat gacaaggatg gtggggactt   2640

cagtggcact ggaggccttc ccgactactc agccgccaac cccattaaag tgacacatcg   2700

gtgctacatc ctagagaacg acacagtcca gtgtgacctg gacctgtaca agtccctgca   2760

ggcctggaaa gaccacaagc tgcacatcga ccacgagatt gaaaccctgc agaacaaaat   2820

taagaacctg agggaagtcc gaggtcacct gaagaaaaag cggccagaag aatgtgactg   2880

tcacaaaatc agctaccaca cccagcacaa aggccgcctc aagcacagag gctccagtct   2940

gcatcctttc aggaagggcc tgcaagagaa ggacaaggtg tggctgttgc gggagcagaa   3000

gcgcaagaag aaactccgca agctgctcaa gcgcctgcag aacaacgaca cgtgcagcat   3060

gccaggcctc acgtgcttca cccacgacaa ccagcactgg cagacggcgc ctttctggac   3120

actggggcct ttctgtgcct gcaccagcgc caacaataac acgtactggt gcatgaggac   3180

catcaatgag actcacaatt tcctcttctg tgaatttgca actggcttcc tagagtactt   3240

tgatctcaac acagacccct accagctgat gaatgcagtg aacacactgg acagggatgt   3300

cctcaaccag ctacacgtac agctcatgga gctgaggagc tgcaagggtt acaagcagtg   3360

taacccccgg actcgaaaca tggacctggg acttaaagat ggaggaagct atgagcaata   3420

caggcagttt cagcgtcgaa agtggccaga aatgaagaga ccttcttcca aatcactggg   3480

acaactgtgg gaaggctggg aaggttaaga aacaacagag gtggacctcc aaaaacatag   3540

aggcatcacc tgactgcaca ggcaatgaaa aaccatgtgg gtgatttcca gcagacctgt   3600

ggtattggcc aggaggcctg agaaagcaag cacgcactct cagtcaacat gacagattct   3660

ggaggataac cagcaggagc agagataact tcaggaagtc catttttgcc cctgcttttg   3720

ctttggatta tacctcacca gctgcacaaa atgcattttt tcgtatcaaa aagtcaccac   3780

taaccctccc ccagaagctc acaaaggaaa acggagagag cgagcgagag agatttcctt   3840

ggaaatttct cccaagggcg aaagtcattg gaatttttaa atcatagggg aaaagcagtc   3900

ctgttctaaa tcctcttatt cttttggttt gtcacaaaga aggaactaag aagcaggaca   3960

gaggcaacgt ggagaggctg aaaacagtgc agagacgttt gacaatgagt cagtagcaca   4020

aaagagatga catttaccta gcactataaa ccctggttgc ctctgaagaa actgccttca   4080

ttgtatatat gtgactattt acatgtaatc aacatgggaa cttttagggg aacctaataa   4140

gaaatcccaa ttttcaggag tggtggtgtc aataaacgct ctgtggccag tgtaaaagaa   4200

aatccctcgc agttgtggac atttctgttc ctgtccagat accatttctc ctagtatttc   4260

tttgttatgt cccagaactg atgttttttt tttaaggtac tgaaaagaaa tgaagttgat   4320

gtatgtccca agttttgatg aaactgtatt tgtaaaaaaa attttgtagt ttaagtattg   4380

tcatacagtg ttcaaaaccc cagccaatga ccagcagttg gtatgaagaa cctttgacat   4440

tttgtaaaag gccatttctt gggagttttt tggtgtgtct gtttttttaa agtattcaag   4500

atactaccag tcaacatctt tttggaagaa aatgccttgg gtttagaaga ttttcttaaa   4560

aggggagtag atggttgtag attgactaaa aagtctacca tacttcaagg gactacaggt   4620

aagtctcata gtataccagc tttggtactt cattttttaa aaaagtatta atcaattgca   4680

aagaaattcg ccttggccaa cccttctttg tgtatcaggt agtctaacct gatacaagta   4740

gttgacagat ttcaactatc aatcaccagt ccaacccatt tctcatttaa cagatgacgg   4800

agataatccc taaaagcacc cacatttgtt tcaatgcccc aaacaggcca aggctcccta   4860

gcaactccct agtggcgttt tttaacttct cagaaactgt taccattatt tgaaataggc   4920

ttccttaacc tcctttaccc ttaacccaac agggatttaa aaaaaaaaaa aaaaaaaaaa   4980

aactctttag gctccaattt taaatagaaa cctttattta caatgacatc caaaatggtc   5040

agcaaagcag tcacagctca ccatccccca taagtcattt catgtggttt caattctttg   5100

caagataaag aataatttct atttttttaa gcaacataat gtaaacttga ttgaaactga   5160

attcattctc aagagtataa gtcaattcct gagaatttaa atattgctct catattttat   5220

tcttcgaaac tccatatatt agaaaggaag agagaaaaca ccctgctcgt ttattaacag   5280

tgtgccttgg agttgaaaac aataaatcaa tccttgaggt tttgctccta ggaacctaat   5340

tgtgaacaaa actcacagct tctgcaaata aaaagggaac tgggcaggca tacatgtaac   5400

tggcaatcca ttctgtttac tttcagctgc acccacctct ggatcaaaga acttctagga   5460

catcaagcca attatcttct gtaataccct acccctaata tagatacccc caactcacct   5520

cagatattaa atactgataa ctaagtagca ctgttattga tatttacacc tttcaatcca   5580

gatgcagttt agaaaagtgg catcataata tgaacattaa caatgtaact tccgtttatt   5640

ttttaaagga agaaacatgt atctccttta tatcattctg atctttataa aatatatata   5700

ttttatttat atatctttgg attcagcaaa aaaaaaaaaa aaaagtaggt actggaaata   5760

tcccacattc taaaagcaga tgaaaagatt atactgttca cccaacagat accaaggttt   5820

gaaaaaatgg ggggtgctgg ggtgtgagga gaggtagaca gcaggagtac aaagaattac   5880

ctaaaaaaga taaagggcaa tacaggtaaa aacaaattat ctcaaagact gcacctatta   5940

aaagaaatct tg                                                       5952


<210>  10178
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  10178

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg 
        835                 840                 845


Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu 
    850                 855                 860


Trp Glu Gly Trp Glu Gly 
865                 870


<210>  10179
<211>  5898
<212>  DNA
<213>  Homo sapiens

<400>  10179
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gagtgagtgt gcgtctgtgt    600

gtcccggcga gggtgcgcgc tcggcgccgg gagcgcggcc agccgagtcc ggaggcatcg    660

ggaggtcgag agccgccggg accccagctc tgcgttcact gccccgtccg gagctggact    720

tcggggccgg ggccggggcc gtgcgccggg gacaggcagg gccgggtcgc gggccgcgcg    780

tcccccaggc cggagatctg cgagtgaaga gggacgaggg aaaagaaaca aagccacaga    840

cgcaacttga gactcccgca tcccaaaaga agcaccagat cagcaaaaaa agaagatggg    900

ccccccgagc ctcgtgctgt gcttgctgtc cgcaactgtg ttctccctgc tgggtggaag    960

ctcggccttc ctgtcgcacc accgcctgaa aggcaggttt cagagggacc gcaggaacat   1020

ccgccccaac atcatcctgg tgctgacgga cgaccaggat gtggagctgg gttccatgca   1080

ggtgatgaac aagacccggc gcatcatgga gcagggcggg gcgcacttca tcaacgcctt   1140

cgtgaccaca cccatgtgct gcccctcacg ctcctccatc ctcactggca agtacgtcca   1200

caaccacaac acctacacca acaatgagaa ctgctcctcg ccctcctggc aggcacagca   1260

cgagagccgc acctttgccg tgtacctcaa tagcactggc taccggacag ctttcttcgg   1320

gaagtatctt aatgaataca acggctccta cgtgccaccc ggctggaagg agtgggtcgg   1380

actccttaaa aactcccgct tttataacta cacgctgtgt cggaacgggg tgaaagagaa   1440

gcacggctcc gactactcca aggattacct cacagacctc atcaccaatg acagcgtgag   1500

cttcttccgc acgtccaaga agatgtaccc gcacaggcca gtcctcatgg tcatcagcca   1560

tgcagccccc cacggccctg aggattcagc cccacaatat tcacgcctct tcccaaacgc   1620

atctcagcac atcacgccga gctacaacta cgcgcccaac ccggacaaac actggatcat   1680

gcgctacacg gggcccatga agcccatcca catggaattc accaacatgc tccagcggaa   1740

gcgcttgcag accctcatgt cggtggacga ctccatggag acgatttaca acatgctggt   1800

tgagacgggc gagctggaca acacgtacat cgtatacacc gccgaccacg gttaccacat   1860

cggccagttt ggcctggtga aagggaaatc catgccatat gagtttgaca tcagggtccc   1920

gttctacgtg aggggcccca acgtggaagc cggctgtctg aatccccaca tcgtcctcaa   1980

cattgacctg gcccccacca tcctggacat tgcaggcctg gacatacctg cggatatgga   2040

cgggaaatcc atcctcaagc tgctggacac ggagcggccg gtgaatcggt ttcacttgaa   2100

aaagaagatg agggtctggc gggactcctt cttggtggag agaggcaagc tgctacacaa   2160

gagagacaat gacaaggtgg acgcccagga ggagaacttt ctgcccaagt accagcgtgt   2220

gaaggacctg tgtcagcgtg ctgagtacca gacggcgtgt gagcagctgg gacagaagtg   2280

gcagtgtgtg gaggacgcca cggggaagct gaagctgcat aagtgcaagg gccccatgcg   2340

gctgggcggc agcagagccc tctccaacct cgtgcccaag tactacgggc agggcagcga   2400

ggcctgcacc tgtgacagcg gggactacaa gctcagcctg gccggacgcc ggaaaaaact   2460

cttcaagaag aagtacaagg ccagctatgt ccgcagtcgc tccatccgct cagtggccat   2520

cgaggtggac ggcagggtgt accacgtagg cctgggtgat gccgcccagc cccgaaacct   2580

caccaagcgg cactggccag gggcccctga ggaccaagat gacaaggatg gtggggactt   2640

cagtggcact ggaggccttc ccgactactc agccgccaac cccattaaag tgacacatcg   2700

gtgctacatc ctagagaacg acacagtcca gtgtgacctg gacctgtaca agtccctgca   2760

ggcctggaaa gaccacaagc tgcacatcga ccacgagatt gaaaccctgc agaacaaaat   2820

taagaacctg agggaagtcc gaggtcacct gaagaaaaag cggccagaag aatgtgactg   2880

tcacaaaatc agctaccaca cccagcacaa aggccgcctc aagcacagag gctccagtct   2940

gcatcctttc aggaagggcc tgcaagagaa ggacaaggtg tggctgttgc gggagcagaa   3000

gcgcaagaag aaactccgca agctgctcaa gcgcctgcag aacaacgaca cgtgcagcat   3060

gccaggcctc acgtgcttca cccacgacaa ccagcactgg cagacggcgc ctttctggac   3120

actggggcct ttctgtgcct gcaccagcgc caacaataac acgtactggt gcatgaggac   3180

catcaatgag actcacaatt tcctcttctg tgaatttgca actggcttcc tagagtactt   3240

tgatctcaac acagacccct accagctgat gaatgcagtg aacacactgg acagggatgt   3300

cctcaaccag ctacacgtac agctcatgga gctgaggagc tgcaagggtt acaagcagtg   3360

taacccccgg actcgaaaca tggacctggg acttaaagat ggaggaagct atgagcaata   3420

caggggacaa ctgtgggaag gctgggaagg ttaagaaaca acagaggtgg acctccaaaa   3480

acatagaggc atcacctgac tgcacaggca atgaaaaacc atgtgggtga tttccagcag   3540

acctgtggta ttggccagga ggcctgagaa agcaagcacg cactctcagt caacatgaca   3600

gattctggag gataaccagc aggagcagag ataacttcag gaagtccatt tttgcccctg   3660

cttttgcttt ggattatacc tcaccagctg cacaaaatgc attttttcgt atcaaaaagt   3720

caccactaac cctcccccag aagctcacaa aggaaaacgg agagagcgag cgagagagat   3780

ttccttggaa atttctccca agggcgaaag tcattggaat ttttaaatca taggggaaaa   3840

gcagtcctgt tctaaatcct cttattcttt tggtttgtca caaagaagga actaagaagc   3900

aggacagagg caacgtggag aggctgaaaa cagtgcagag acgtttgaca atgagtcagt   3960

agcacaaaag agatgacatt tacctagcac tataaaccct ggttgcctct gaagaaactg   4020

ccttcattgt atatatgtga ctatttacat gtaatcaaca tgggaacttt taggggaacc   4080

taataagaaa tcccaatttt caggagtggt ggtgtcaata aacgctctgt ggccagtgta   4140

aaagaaaatc cctcgcagtt gtggacattt ctgttcctgt ccagatacca tttctcctag   4200

tatttctttg ttatgtccca gaactgatgt ttttttttta aggtactgaa aagaaatgaa   4260

gttgatgtat gtcccaagtt ttgatgaaac tgtatttgta aaaaaaattt tgtagtttaa   4320

gtattgtcat acagtgttca aaaccccagc caatgaccag cagttggtat gaagaacctt   4380

tgacattttg taaaaggcca tttcttggga gttttttggt gtgtctgttt ttttaaagta   4440

ttcaagatac taccagtcaa catctttttg gaagaaaatg ccttgggttt agaagatttt   4500

cttaaaaggg gagtagatgg ttgtagattg actaaaaagt ctaccatact tcaagggact   4560

acaggtaagt ctcatagtat accagctttg gtacttcatt ttttaaaaaa gtattaatca   4620

attgcaaaga aattcgcctt ggccaaccct tctttgtgta tcaggtagtc taacctgata   4680

caagtagttg acagatttca actatcaatc accagtccaa cccatttctc atttaacaga   4740

tgacggagat aatccctaaa agcacccaca tttgtttcaa tgccccaaac aggccaaggc   4800

tccctagcaa ctccctagtg gcgtttttta acttctcaga aactgttacc attatttgaa   4860

ataggcttcc ttaacctcct ttacccttaa cccaacaggg atttaaaaaa aaaaaaaaaa   4920

aaaaaaaact ctttaggctc caattttaaa tagaaacctt tatttacaat gacatccaaa   4980

atggtcagca aagcagtcac agctcaccat cccccataag tcatttcatg tggtttcaat   5040

tctttgcaag ataaagaata atttctattt ttttaagcaa cataatgtaa acttgattga   5100

aactgaattc attctcaaga gtataagtca attcctgaga atttaaatat tgctctcata   5160

ttttattctt cgaaactcca tatattagaa aggaagagag aaaacaccct gctcgtttat   5220

taacagtgtg ccttggagtt gaaaacaata aatcaatcct tgaggttttg ctcctaggaa   5280

cctaattgtg aacaaaactc acagcttctg caaataaaaa gggaactggg caggcataca   5340

tgtaactggc aatccattct gtttactttc agctgcaccc acctctggat caaagaactt   5400

ctaggacatc aagccaatta tcttctgtaa taccctaccc ctaatataga tacccccaac   5460

tcacctcaga tattaaatac tgataactaa gtagcactgt tattgatatt tacacctttc   5520

aatccagatg cagtttagaa aagtggcatc ataatatgaa cattaacaat gtaacttccg   5580

tttatttttt aaaggaagaa acatgtatct cctttatatc attctgatct ttataaaata   5640

tatatatttt atttatatat ctttggattc agcaaaaaaa aaaaaaaaaa gtaggtactg   5700

gaaatatccc acattctaaa agcagatgaa aagattatac tgttcaccca acagatacca   5760

aggtttgaaa aaatgggggg tgctggggtg tgaggagagg tagacagcag gagtacaaag   5820

aattacctaa aaaagataaa gggcaataca ggtaaaaaca aattatctca aagactgcac   5880

ctattaaaag aaatcttg                                                 5898


<210>  10180
<211>  852
<212>  PRT
<213>  Homo sapiens

<400>  10180

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gly Gln Leu Trp Glu 
        835                 840                 845


Gly Trp Glu Gly 
    850


<210>  10181
<211>  5739
<212>  DNA
<213>  Homo sapiens

<400>  10181
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gaatctgcga gtgaagaggg    600

acgagggaaa agaaacaaag ccacagacgc aacttgagac tcccgcatcc caaaagaagc    660

accagatcag caaaaaaaga agatgggccc cccgagcctc gtgctgtgct tgctgtccgc    720

aactgtgttc tccctgctgg gtggaagctc ggccttcctg tcgcaccacc gcctgaaagg    780

caggtttcag agggaccgca ggaacatccg ccccaacatc atcctggtgc tgacggacga    840

ccaggatgtg gagctgggtt ccatgcaggt gatgaacaag acccggcgca tcatggagca    900

gggcggggcg cacttcatca acgccttcgt gaccacaccc atgtgctgcc cctcacgctc    960

ctccatcctc actggcaagt acgtccacaa ccacaacacc tacaccaaca atgagaactg   1020

ctcctcgccc tcctggcagg cacagcacga gagccgcacc tttgccgtgt acctcaatag   1080

cactggctac cggacagctt tcttcgggaa gtatcttaat gaatacaacg gctcctacgt   1140

gccacccggc tggaaggagt gggtcggact ccttaaaaac tcccgctttt ataactacac   1200

gctgtgtcgg aacggggtga aagagaagca cggctccgac tactccaagg attacctcac   1260

agacctcatc accaatgaca gcgtgagctt cttccgcacg tccaagaaga tgtacccgca   1320

caggccagtc ctcatggtca tcagccatgc agccccccac ggccctgagg attcagcccc   1380

acaatattca cgcctcttcc caaacgcatc tcagcacatc acgccgagct acaactacgc   1440

gcccaacccg gacaaacact ggatcatgcg ctacacgggg cccatgaagc ccatccacat   1500

ggaattcacc aacatgctcc agcggaagcg cttgcagacc ctcatgtcgg tggacgactc   1560

catggagacg atttacaaca tgctggttga gacgggcgag ctggacaaca cgtacatcgt   1620

atacaccgcc gaccacggtt accacatcgg ccagtttggc ctggtgaaag ggaaatccat   1680

gccatatgag tttgacatca gggtcccgtt ctacgtgagg ggccccaacg tggaagccgg   1740

ctgtctgaat ccccacatcg tcctcaacat tgacctggcc cccaccatcc tggacattgc   1800

aggcctggac atacctgcgg atatggacgg gaaatccatc ctcaagctgc tggacacgga   1860

gcggccggtg aatcggtttc acttgaaaaa gaagatgagg gtctggcggg actccttctt   1920

ggtggagaga ggcaagctgc tacacaagag agacaatgac aaggtggacg cccaggagga   1980

gaactttctg cccaagtacc agcgtgtgaa ggacctgtgt cagcgtgctg agtaccagac   2040

ggcgtgtgag cagctgggac agaagtggca gtgtgtggag gacgccacgg ggaagctgaa   2100

gctgcataag tgcaagggcc ccatgcggct gggcggcagc agagccctct ccaacctcgt   2160

gcccaagtac tacgggcagg gcagcgaggc ctgcacctgt gacagcgggg actacaagct   2220

cagcctggcc ggacgccgga aaaaactctt caagaagaag tacaaggcca gctatgtccg   2280

cagtcgctcc atccgctcag tggccatcga ggtggacggc agggtgtacc acgtaggcct   2340

gggtgatgcc gcccagcccc gaaacctcac caagcggcac tggccagggg cccctgagga   2400

ccaagatgac aaggatggtg gggacttcag tggcactgga ggccttcccg actactcagc   2460

cgccaacccc attaaagtga cacatcggtg ctacatccta gagaacgaca cagtccagtg   2520

tgacctggac ctgtacaagt ccctgcaggc ctggaaagac cacaagctgc acatcgacca   2580

cgagattgaa accctgcaga acaaaattaa gaacctgagg gaagtccgag gtcacctgaa   2640

gaaaaagcgg ccagaagaat gtgactgtca caaaatcagc taccacaccc agcacaaagg   2700

ccgcctcaag cacagaggct ccagtctgca tcctttcagg aagggcctgc aagagaagga   2760

caaggtgtgg ctgttgcggg agcagaagcg caagaagaaa ctccgcaagc tgctcaagcg   2820

cctgcagaac aacgacacgt gcagcatgcc aggcctcacg tgcttcaccc acgacaacca   2880

gcactggcag acggcgcctt tctggacact ggggcctttc tgtgcctgca ccagcgccaa   2940

caataacacg tactggtgca tgaggaccat caatgagact cacaatttcc tcttctgtga   3000

atttgcaact ggcttcctag agtactttga tctcaacaca gacccctacc agctgatgaa   3060

tgcagtgaac acactggaca gggatgtcct caaccagcta cacgtacagc tcatggagct   3120

gaggagctgc aagggttaca agcagtgtaa cccccggact cgaaacatgg acctgggact   3180

taaagatgga ggaagctatg agcaatacag gcagtttcag cgtcgaaagt ggccagaaat   3240

gaagagacct tcttccaaat cactgggaca actgtgggaa ggctgggaag gttaagaaac   3300

aacagaggtg gacctccaaa aacatagagg catcacctga ctgcacaggc aatgaaaaac   3360

catgtgggtg atttccagca gacctgtggt attggccagg aggcctgaga aagcaagcac   3420

gcactctcag tcaacatgac agattctgga ggataaccag caggagcaga gataacttca   3480

ggaagtccat ttttgcccct gcttttgctt tggattatac ctcaccagct gcacaaaatg   3540

cattttttcg tatcaaaaag tcaccactaa ccctccccca gaagctcaca aaggaaaacg   3600

gagagagcga gcgagagaga tttccttgga aatttctccc aagggcgaaa gtcattggaa   3660

tttttaaatc ataggggaaa agcagtcctg ttctaaatcc tcttattctt ttggtttgtc   3720

acaaagaagg aactaagaag caggacagag gcaacgtgga gaggctgaaa acagtgcaga   3780

gacgtttgac aatgagtcag tagcacaaaa gagatgacat ttacctagca ctataaaccc   3840

tggttgcctc tgaagaaact gccttcattg tatatatgtg actatttaca tgtaatcaac   3900

atgggaactt ttaggggaac ctaataagaa atcccaattt tcaggagtgg tggtgtcaat   3960

aaacgctctg tggccagtgt aaaagaaaat ccctcgcagt tgtggacatt tctgttcctg   4020

tccagatacc atttctccta gtatttcttt gttatgtccc agaactgatg tttttttttt   4080

aaggtactga aaagaaatga agttgatgta tgtcccaagt tttgatgaaa ctgtatttgt   4140

aaaaaaaatt ttgtagttta agtattgtca tacagtgttc aaaaccccag ccaatgacca   4200

gcagttggta tgaagaacct ttgacatttt gtaaaaggcc atttcttggg agttttttgg   4260

tgtgtctgtt tttttaaagt attcaagata ctaccagtca acatcttttt ggaagaaaat   4320

gccttgggtt tagaagattt tcttaaaagg ggagtagatg gttgtagatt gactaaaaag   4380

tctaccatac ttcaagggac tacaggtaag tctcatagta taccagcttt ggtacttcat   4440

tttttaaaaa agtattaatc aattgcaaag aaattcgcct tggccaaccc ttctttgtgt   4500

atcaggtagt ctaacctgat acaagtagtt gacagatttc aactatcaat caccagtcca   4560

acccatttct catttaacag atgacggaga taatccctaa aagcacccac atttgtttca   4620

atgccccaaa caggccaagg ctccctagca actccctagt ggcgtttttt aacttctcag   4680

aaactgttac cattatttga aataggcttc cttaacctcc tttaccctta acccaacagg   4740

gatttaaaaa aaaaaaaaaa aaaaaaaaac tctttaggct ccaattttaa atagaaacct   4800

ttatttacaa tgacatccaa aatggtcagc aaagcagtca cagctcacca tcccccataa   4860

gtcatttcat gtggtttcaa ttctttgcaa gataaagaat aatttctatt tttttaagca   4920

acataatgta aacttgattg aaactgaatt cattctcaag agtataagtc aattcctgag   4980

aatttaaata ttgctctcat attttattct tcgaaactcc atatattaga aaggaagaga   5040

gaaaacaccc tgctcgttta ttaacagtgt gccttggagt tgaaaacaat aaatcaatcc   5100

ttgaggtttt gctcctagga acctaattgt gaacaaaact cacagcttct gcaaataaaa   5160

agggaactgg gcaggcatac atgtaactgg caatccattc tgtttacttt cagctgcacc   5220

cacctctgga tcaaagaact tctaggacat caagccaatt atcttctgta ataccctacc   5280

cctaatatag atacccccaa ctcacctcag atattaaata ctgataacta agtagcactg   5340

ttattgatat ttacaccttt caatccagat gcagtttaga aaagtggcat cataatatga   5400

acattaacaa tgtaacttcc gtttattttt taaaggaaga aacatgtatc tcctttatat   5460

cattctgatc tttataaaat atatatattt tatttatata tctttggatt cagcaaaaaa   5520

aaaaaaaaaa agtaggtact ggaaatatcc cacattctaa aagcagatga aaagattata   5580

ctgttcaccc aacagatacc aaggtttgaa aaaatggggg gtgctggggt gtgaggagag   5640

gtagacagca ggagtacaaa gaattaccta aaaaagataa agggcaatac aggtaaaaac   5700

aaattatctc aaagactgca cctattaaaa gaaatcttg                          5739


<210>  10182
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  10182

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg 
        835                 840                 845


Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu 
    850                 855                 860


Trp Glu Gly Trp Glu Gly 
865                 870


<210>  10183
<211>  743
<212>  DNA
<213>  Homo sapiens

<400>  10183
ctctcctcac accccagcac cccccatttt ttcaaacctt ggtatctgtt gggtgaacag     60

tataatcttt tcatctgctt ttagaatgtg ggatatttcc agtacctact tttttttttt    120

ttttttgctg aatccaaaga tatataaata aaatatatat attttataaa gatcagaatg    180

atataaagga gatacatgtt tcttccttta aaaaataaac ggaagttaca ttgttaatgt    240

tcatattatg atgccacttt tctaaactgc atctggattg aaaggtgtaa atatcaataa    300

cagtgctact tagttatcag tatttaatat ctgaggtgag ttgggggtat ctatattagg    360

ggtagggtat tacagaagat aattggcttg atgtcctaga agttctttga tccagaggtg    420

ggtgcagctg tagtcccttg aagtatggta gactttttag tcaatctaca accatctact    480

ccccttttaa gaaaatcttc taaacccaag gcattttctt ccaaaaagat gttgactggt    540

agtatcttga atactttaaa aaaacagaca caccaaaaaa ctcccaagaa atggcctttt    600

acaaaatgtc aaaggttctt cataccaact gctggtcatt ggctggggtt ttgaacactg    660

tatgacaata cttaaactac aaaatttttt ttacaaatac agtttcatca aaacttggga    720

catacatcaa cttcatttct ttt                                            743


<210>  10184
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  10184

Met Val Asp Phe Leu Val Asn Leu Gln Pro Ser Thr Pro Leu Leu Arg 
1               5                   10                  15


Lys Ser Ser Lys Pro Lys Ala Phe Ser Ser Lys Lys Met Leu Thr Gly 
            20                  25                  30


Ser Ile Leu Asn Thr Leu Lys Lys Gln Thr His Gln Lys Thr Pro Lys 
        35                  40                  45


Lys Trp Pro Phe Thr Lys Cys Gln Arg Phe Phe Ile Pro Thr Ala Gly 
    50                  55                  60


His Trp Leu Gly Phe 
65


<210>  10185
<211>  1645
<212>  DNA
<213>  Homo sapiens

<400>  10185
ctttctgtcc tctggagcac agatgttcat gcctgcatct acctccctca ccataactaa     60

ggtcagcgct gaatgaagcc atcagggtcc tgaaactgat catggtgaca ctggatttta    120

ggcaatctac aaggctatct aggagactta gggcaggttc ccctcataat tcagtctacc    180

cctcataatt cagtctactc tgagtaggga acactatcag catcatggga ttgtgacaaa    240

aaagcataag atggttttct ggtgtgttgg ggttgttttg cctaaactat ctgctcctgt    300

tttgtttttc atttctcctt catttaggac ttaaagatgg aggaagctat gagcaataca    360

ggtatttcgt tttattatta aagcctaaac aaagttctcc tatcttggcc catccttcag    420

tctcatctct gtgagtctgc acctgttatc ttgagaaact gcccttccct ctggtctgcc    480

cgagaccagg atcacccacc aaagataggt gtcacctagg agaccttctt tgtatagttc    540

tttggggact ttttctttct tggtgatggt taacattcat tctcctttga cacttgaaaa    600

cttaggcagt ttcagcgtcg aaagtggcca gaaatgaaga gaccttcttc caaatcactg    660

ggacaactgt gggaaggctg ggaaggttaa gaaacaacag aggtggacct ccaaaaacat    720

agaggcatca cctgactgca caggcaatga aaaaccatgt gggtgatttc cagcagacct    780

gtggtattgg ccaggaggcc tgagaaagca agcacgcact ctcagtcaac atgacagatt    840

ctggaggata accagcagga gcagagataa cttcaggaag tccatttttg cccctgcttt    900

tgctttggat tatacctcac cagctgcaca aaatgcattt tttcgtatca aaaagtcacc    960

actaaccctc ccccagaagc tcacaaagga aaacggagag agcgagcgag agagatttcc   1020

ttggaaattt ctcccaaggg cgaaagtcat tggaattttt aaatcatagg ggaaaagcag   1080

tcctgttcta aatcctctta ttcttttggt ttgtcacaaa gaaggaacta agaagcagga   1140

cagaggcaac gtggagaggc tgaaaacagt gcagagacgt ttgacaatga gtcagtagca   1200

caaaagagat gacatttacc tagcactata aaccctggtt gcctctgaag aaactgcctt   1260

cattgtatat atgtgactat ttacatgtaa tcaacatggg aacttttagg ggaacctaat   1320

aagaaatccc aattttcagg agtggtggtg tcaataaacg ctctgtggcc agtgtaaaag   1380

aaaatccctc gcagttgtgg acatttctgt tcctgtccag ataccatttc tcctagtatt   1440

tctttgttat gtcccagaac tgatgttttt tttttaaggt actgaaaaga aatgaagttg   1500

atgtatgtcc caagttttga tgaaactgta tttgtaaaaa aaattttgta gtttaagtat   1560

tgtcatacag tgttcaaaac cccagccaat gaccagcagt tggtatgaag aacctttgac   1620

attttgtaaa aggccatttc ttggg                                         1645


<210>  10186
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  10186

Arg Asp Leu Leu Pro Asn His Trp Asp Asn Cys Gly Lys Ala Gly Lys 
1               5                   10                  15


Val Lys Lys Gln Gln Arg Trp Thr Ser Lys Asn Ile Glu Ala Ser Pro 
            20                  25                  30


Asp Cys Thr Gly Asn Glu Lys Pro Cys Gly 
        35                  40


<210>  10187
<211>  4463
<212>  DNA
<213>  Homo sapiens

<400>  10187
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gagtgagtgt gcgtctgtgt    600

gtcccggcga gggtgcgcgc tcggcgccgg gagcgcggcc agccgagtcc ggaggcatcg    660

ggaggtcgag agccgccggg accccagctc tgcgttcact gccccgtccg gagctggact    720

tcggggccgg ggccggggcc gtgcgccggg gacaggcagg gccgggtcgc gggccgcgcg    780

tcccccaggc cggagatctg cgagtgaaga gggacgaggg aaaagaaaca aagccacaga    840

cgcaacttga gactcccgca tcccaaaaga agcaccagat cagcaaaaaa agaagatggg    900

ccccccgagc ctcgtgctgt gcttgctgtc cgcaactgtg ttctccctgc tgggtggaag    960

ctcggccttc ctgtcgcacc accgcctgaa aggcaggttt cagagggacc gcaggaacat   1020

ccgccccaac atcatcctgg tgctgacgga cgaccaggat gtggagctgg gttccatgca   1080

ggtgatgaac aagacccggc gcatcatgga gcagggcggg gcgcacttca tcaacgcctt   1140

cgtgaccaca cccatgtgct gcccctcacg ctcctccatc ctcactggca agtacgtcca   1200

caaccacaac acctacacca acaatgagaa ctgctcctcg ccctcctggc aggcacagca   1260

cgagagccgc acctttgccg tgtacctcaa tagcactggc taccggacag ctttcttcgg   1320

gaagtatctt aatgaataca acggctccta cgtgccaccc ggctggaagg agtgggtcgg   1380

actccttaaa aactcccgct tttataacta cacgctgtgt cggaacgggg tgaaagagaa   1440

gcacggctcc gactactcca aggattacct cacagacctc atcaccaatg acagcgtgag   1500

cttcttccgc acgtccaaga agatgtaccc gcacaggcca gtcctcatgg tcatcagcca   1560

tgcagccccc cacggccctg aggattcagc cccacaatat tcacgcctct tcccaaacgc   1620

atctcagcac atcacgccga gctacaacta cgcgcccaac ccggacaaac actggatcat   1680

gcgctacacg gggcccatga agcccatcca catggaattc accaacatgc tccagcggaa   1740

gcgcttgcag accctcatgt cggtggacga ctccatggag acgatttaca acatgctggt   1800

tgagacgggc gagctggaca acacgtacat cgtatacacc gccgaccacg gttaccacat   1860

cggccagttt ggcctggtga aagggaaatc catgccatat gagtttgaca tcagggtccc   1920

gttctacgtg aggggcccca acgtggaagc cggctgtctg aatccccaca tcgtcctcaa   1980

cattgacctg gcccccacca tcctggacat tgcaggcctg gacatacctg cggatatgga   2040

cgggaaatcc atcctcaagc tgctggacac ggagcggccg gtgaatcggt ttcacttgaa   2100

aaagaagatg agggtctggc gggactcctt cttggtggag agaggcaagc tgctacacaa   2160

gagagacaat gacaaggtgg acgcccagga ggagaacttt ctgcccaagt accagcgtgt   2220

gaaggacctg tgtcagcgtg ctgagtacca gacggcgtgt gagcagctgg gacagaagtg   2280

gcagtgtgtg gaggacgcca cggggaagct gaagctgcat aagtgcaagg gccccatgcg   2340

gctgggcggc agcagagccc tctccaacct cgtgcccaag tactacgggc agggcagcga   2400

ggcctgcacc tgtgacagcg gggactacaa gctcagcctg gccggacgcc ggaaaaaact   2460

cttcaagaag aagtacaagg ccagctatgt ccgcagtcgc tccatccgct cagtggccat   2520

cgaggtggac ggcagggtgt accacgtagg cctgggtgat gccgcccagc cccgaaacct   2580

caccaagcgg cactggccag gggcccctga ggaccaagat gacaaggatg gtggggactt   2640

cagtggcact ggaggccttc ccgactactc agccgccaac cccattaaag tgacacatcg   2700

gtgctacatc ctagagaacg acacagtcca gtgtgacctg gacctgtaca agtccctgca   2760

ggcctggaaa gaccacaagc tgcacatcga ccacgagatt gaaaccctgc agaacaaaat   2820

taagaacctg agggaagtcc gaggtcacct gaagaaaaag cggccagaag aatgtgactg   2880

tcacaaaatc agctaccaca cccagcacaa aggccgcctc aagcacagag gctccagtct   2940

gcatcctttc aggaagggcc tgcaagagaa ggacaaggtg tggctgttgc gggagcagaa   3000

gcgcaagaag aaactccgca agctgctcaa gcgcctgcag aacaacgaca cgtgcagcat   3060

gccaggcctc acgtgcttca cccacgacaa ccagcactgg cagacggcgc ctttctggac   3120

actggggcct ttctgtgcct gcaccagcgc caacaataac acgtactggt gcatgaggac   3180

catcaatgag actcacaatt tcctcttctg tgaatttgca actggcttcc tagagtactt   3240

tgatctcaac acagacccct accagctgat gaatgcagtg aacacactgg acagggatgt   3300

cctcaaccag ctacacgtac agctcatgga gctgaggagc tgcaagggtt acaagcagtg   3360

taacccccgg actcgaaaca tggacctggg acttaaagat ggaggaagct atgagcaata   3420

caggcagttt cagcgtcgaa agtggccaga aatgaagaga ccttcttcca aatcactggg   3480

acaactgtgg gaaggctggg aaggttaaga aacaacagag gtggacctcc aaaaacatag   3540

aggcatcacc tgactgcaca ggcaatgaaa aaccatgtgg gtgatttcca gcagacctgt   3600

ggtattggcc aggaggcctg agaaagcaag cacgcactct cagtcaacat gacagattct   3660

ggaggataac cagcaggagc agagataact tcaggaagtc catttttgcc cctgcttttg   3720

ctttggatta tacctcacca gctgcacaaa atgcattttt tcgtatcaaa aagtcaccac   3780

taaccctccc ccagaagctc acaaaggaaa acggagagag cgagcgagag agatttcctt   3840

ggaaatttct cccaagggcg aaagtcattg gaatttttaa atcatagggg aaaagcagtc   3900

ctgttctaaa tcctcttatt cttttggttt gtcacaaaga aggaactaag aagcaggaca   3960

gaggcaacgt ggagaggctg aaaacagtgc agagacgttt gacaatgagt cagtagcaca   4020

aaagagatga catttaccta gcactataaa ccctggttgc ctctgaagaa actgccttca   4080

ttgtatatat gtgactattt acatgtaatc aacatgggaa cttttagggg aacctaataa   4140

gaaatcccaa ttttcaggag tggtggtgtc aataaacgct ctgtggccag tgtaaaagaa   4200

aatccctcgc agttgtggac atttctgttc ctgtccagat accatttctc ctagtatttc   4260

tttgttatgt cccagaactg atgttttttt tttaaggtac tgaaaagaaa tgaagttgat   4320

gtatgtccca agttttgatg aaactgtatt tgtaaaaaaa attttgtagt ttaagtattg   4380

tcatacagtg ttcaaaaccc cagccaatga ccagcagttg gtatgaagaa cctttgacat   4440

tttgtaaaag gccatttctt ggg                                           4463


<210>  10188
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  10188

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg 
        835                 840                 845


Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu 
    850                 855                 860


Trp Glu Gly Trp Glu Gly 
865                 870


<210>  10189
<211>  4250
<212>  DNA
<213>  Homo sapiens

<400>  10189
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gaatctgcga gtgaagaggg    600

acgagggaaa agaaacaaag ccacagacgc aacttgagac tcccgcatcc caaaagaagc    660

accagatcag caaaaaaaga agatgggccc cccgagcctc gtgctgtgct tgctgtccgc    720

aactgtgttc tccctgctgg gtggaagctc ggccttcctg tcgcaccacc gcctgaaagg    780

caggtttcag agggaccgca ggaacatccg ccccaacatc atcctggtgc tgacggacga    840

ccaggatgtg gagctgggtt ccatgcaggt gatgaacaag acccggcgca tcatggagca    900

gggcggggcg cacttcatca acgccttcgt gaccacaccc atgtgctgcc cctcacgctc    960

ctccatcctc actggcaagt acgtccacaa ccacaacacc tacaccaaca atgagaactg   1020

ctcctcgccc tcctggcagg cacagcacga gagccgcacc tttgccgtgt acctcaatag   1080

cactggctac cggacagctt tcttcgggaa gtatcttaat gaatacaacg gctcctacgt   1140

gccacccggc tggaaggagt gggtcggact ccttaaaaac tcccgctttt ataactacac   1200

gctgtgtcgg aacggggtga aagagaagca cggctccgac tactccaagg attacctcac   1260

agacctcatc accaatgaca gcgtgagctt cttccgcacg tccaagaaga tgtacccgca   1320

caggccagtc ctcatggtca tcagccatgc agccccccac ggccctgagg attcagcccc   1380

acaatattca cgcctcttcc caaacgcatc tcagcacatc acgccgagct acaactacgc   1440

gcccaacccg gacaaacact ggatcatgcg ctacacgggg cccatgaagc ccatccacat   1500

ggaattcacc aacatgctcc agcggaagcg cttgcagacc ctcatgtcgg tggacgactc   1560

catggagacg atttacaaca tgctggttga gacgggcgag ctggacaaca cgtacatcgt   1620

atacaccgcc gaccacggtt accacatcgg ccagtttggc ctggtgaaag ggaaatccat   1680

gccatatgag tttgacatca gggtcccgtt ctacgtgagg ggccccaacg tggaagccgg   1740

ctgtctgaat ccccacatcg tcctcaacat tgacctggcc cccaccatcc tggacattgc   1800

aggcctggac atacctgcgg atatggacgg gaaatccatc ctcaagctgc tggacacgga   1860

gcggccggtg aatcggtttc acttgaaaaa gaagatgagg gtctggcggg actccttctt   1920

ggtggagaga ggcaagctgc tacacaagag agacaatgac aaggtggacg cccaggagga   1980

gaactttctg cccaagtacc agcgtgtgaa ggacctgtgt cagcgtgctg agtaccagac   2040

ggcgtgtgag cagctgggac agaagtggca gtgtgtggag gacgccacgg ggaagctgaa   2100

gctgcataag tgcaagggcc ccatgcggct gggcggcagc agagccctct ccaacctcgt   2160

gcccaagtac tacgggcagg gcagcgaggc ctgcacctgt gacagcgggg actacaagct   2220

cagcctggcc ggacgccgga aaaaactctt caagaagaag tacaaggcca gctatgtccg   2280

cagtcgctcc atccgctcag tggccatcga ggtggacggc agggtgtacc acgtaggcct   2340

gggtgatgcc gcccagcccc gaaacctcac caagcggcac tggccagggg cccctgagga   2400

ccaagatgac aaggatggtg gggacttcag tggcactgga ggccttcccg actactcagc   2460

cgccaacccc attaaagtga cacatcggtg ctacatccta gagaacgaca cagtccagtg   2520

tgacctggac ctgtacaagt ccctgcaggc ctggaaagac cacaagctgc acatcgacca   2580

cgagattgaa accctgcaga acaaaattaa gaacctgagg gaagtccgag gtcacctgaa   2640

gaaaaagcgg ccagaagaat gtgactgtca caaaatcagc taccacaccc agcacaaagg   2700

ccgcctcaag cacagaggct ccagtctgca tcctttcagg aagggcctgc aagagaagga   2760

caaggtgtgg ctgttgcggg agcagaagcg caagaagaaa ctccgcaagc tgctcaagcg   2820

cctgcagaac aacgacacgt gcagcatgcc aggcctcacg tgcttcaccc acgacaacca   2880

gcactggcag acggcgcctt tctggacact ggggcctttc tgtgcctgca ccagcgccaa   2940

caataacacg tactggtgca tgaggaccat caatgagact cacaatttcc tcttctgtga   3000

atttgcaact ggcttcctag agtactttga tctcaacaca gacccctacc agctgatgaa   3060

tgcagtgaac acactggaca gggatgtcct caaccagcta cacgtacagc tcatggagct   3120

gaggagctgc aagggttaca agcagtgtaa cccccggact cgaaacatgg acctgggact   3180

taaagatgga ggaagctatg agcaatacag gcagtttcag cgtcgaaagt ggccagaaat   3240

gaagagacct tcttccaaat cactgggaca actgtgggaa ggctgggaag gttaagaaac   3300

aacagaggtg gacctccaaa aacatagagg catcacctga ctgcacaggc aatgaaaaac   3360

catgtgggtg atttccagca gacctgtggt attggccagg aggcctgaga aagcaagcac   3420

gcactctcag tcaacatgac agattctgga ggataaccag caggagcaga gataacttca   3480

ggaagtccat ttttgcccct gcttttgctt tggattatac ctcaccagct gcacaaaatg   3540

cattttttcg tatcaaaaag tcaccactaa ccctccccca gaagctcaca aaggaaaacg   3600

gagagagcga gcgagagaga tttccttgga aatttctccc aagggcgaaa gtcattggaa   3660

tttttaaatc ataggggaaa agcagtcctg ttctaaatcc tcttattctt ttggtttgtc   3720

acaaagaagg aactaagaag caggacagag gcaacgtgga gaggctgaaa acagtgcaga   3780

gacgtttgac aatgagtcag tagcacaaaa gagatgacat ttacctagca ctataaaccc   3840

tggttgcctc tgaagaaact gccttcattg tatatatgtg actatttaca tgtaatcaac   3900

atgggaactt ttaggggaac ctaataagaa atcccaattt tcaggagtgg tggtgtcaat   3960

aaacgctctg tggccagtgt aaaagaaaat ccctcgcagt tgtggacatt tctgttcctg   4020

tccagatacc atttctccta gtatttcttt gttatgtccc agaactgatg tttttttttt   4080

aaggtactga aaagaaatga agttgatgta tgtcccaagt tttgatgaaa ctgtatttgt   4140

aaaaaaaatt ttgtagttta agtattgtca tacagtgttc aaaaccccag ccaatgacca   4200

gcagttggta tgaagaacct ttgacatttt gtaaaaggcc atttcttggg              4250


<210>  10190
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  10190

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg 
        835                 840                 845


Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu 
    850                 855                 860


Trp Glu Gly Trp Glu Gly 
865                 870


<210>  10191
<211>  4409
<212>  DNA
<213>  Homo sapiens

<400>  10191
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gagtgagtgt gcgtctgtgt    600

gtcccggcga gggtgcgcgc tcggcgccgg gagcgcggcc agccgagtcc ggaggcatcg    660

ggaggtcgag agccgccggg accccagctc tgcgttcact gccccgtccg gagctggact    720

tcggggccgg ggccggggcc gtgcgccggg gacaggcagg gccgggtcgc gggccgcgcg    780

tcccccaggc cggagatctg cgagtgaaga gggacgaggg aaaagaaaca aagccacaga    840

cgcaacttga gactcccgca tcccaaaaga agcaccagat cagcaaaaaa agaagatggg    900

ccccccgagc ctcgtgctgt gcttgctgtc cgcaactgtg ttctccctgc tgggtggaag    960

ctcggccttc ctgtcgcacc accgcctgaa aggcaggttt cagagggacc gcaggaacat   1020

ccgccccaac atcatcctgg tgctgacgga cgaccaggat gtggagctgg gttccatgca   1080

ggtgatgaac aagacccggc gcatcatgga gcagggcggg gcgcacttca tcaacgcctt   1140

cgtgaccaca cccatgtgct gcccctcacg ctcctccatc ctcactggca agtacgtcca   1200

caaccacaac acctacacca acaatgagaa ctgctcctcg ccctcctggc aggcacagca   1260

cgagagccgc acctttgccg tgtacctcaa tagcactggc taccggacag ctttcttcgg   1320

gaagtatctt aatgaataca acggctccta cgtgccaccc ggctggaagg agtgggtcgg   1380

actccttaaa aactcccgct tttataacta cacgctgtgt cggaacgggg tgaaagagaa   1440

gcacggctcc gactactcca aggattacct cacagacctc atcaccaatg acagcgtgag   1500

cttcttccgc acgtccaaga agatgtaccc gcacaggcca gtcctcatgg tcatcagcca   1560

tgcagccccc cacggccctg aggattcagc cccacaatat tcacgcctct tcccaaacgc   1620

atctcagcac atcacgccga gctacaacta cgcgcccaac ccggacaaac actggatcat   1680

gcgctacacg gggcccatga agcccatcca catggaattc accaacatgc tccagcggaa   1740

gcgcttgcag accctcatgt cggtggacga ctccatggag acgatttaca acatgctggt   1800

tgagacgggc gagctggaca acacgtacat cgtatacacc gccgaccacg gttaccacat   1860

cggccagttt ggcctggtga aagggaaatc catgccatat gagtttgaca tcagggtccc   1920

gttctacgtg aggggcccca acgtggaagc cggctgtctg aatccccaca tcgtcctcaa   1980

cattgacctg gcccccacca tcctggacat tgcaggcctg gacatacctg cggatatgga   2040

cgggaaatcc atcctcaagc tgctggacac ggagcggccg gtgaatcggt ttcacttgaa   2100

aaagaagatg agggtctggc gggactcctt cttggtggag agaggcaagc tgctacacaa   2160

gagagacaat gacaaggtgg acgcccagga ggagaacttt ctgcccaagt accagcgtgt   2220

gaaggacctg tgtcagcgtg ctgagtacca gacggcgtgt gagcagctgg gacagaagtg   2280

gcagtgtgtg gaggacgcca cggggaagct gaagctgcat aagtgcaagg gccccatgcg   2340

gctgggcggc agcagagccc tctccaacct cgtgcccaag tactacgggc agggcagcga   2400

ggcctgcacc tgtgacagcg gggactacaa gctcagcctg gccggacgcc ggaaaaaact   2460

cttcaagaag aagtacaagg ccagctatgt ccgcagtcgc tccatccgct cagtggccat   2520

cgaggtggac ggcagggtgt accacgtagg cctgggtgat gccgcccagc cccgaaacct   2580

caccaagcgg cactggccag gggcccctga ggaccaagat gacaaggatg gtggggactt   2640

cagtggcact ggaggccttc ccgactactc agccgccaac cccattaaag tgacacatcg   2700

gtgctacatc ctagagaacg acacagtcca gtgtgacctg gacctgtaca agtccctgca   2760

ggcctggaaa gaccacaagc tgcacatcga ccacgagatt gaaaccctgc agaacaaaat   2820

taagaacctg agggaagtcc gaggtcacct gaagaaaaag cggccagaag aatgtgactg   2880

tcacaaaatc agctaccaca cccagcacaa aggccgcctc aagcacagag gctccagtct   2940

gcatcctttc aggaagggcc tgcaagagaa ggacaaggtg tggctgttgc gggagcagaa   3000

gcgcaagaag aaactccgca agctgctcaa gcgcctgcag aacaacgaca cgtgcagcat   3060

gccaggcctc acgtgcttca cccacgacaa ccagcactgg cagacggcgc ctttctggac   3120

actggggcct ttctgtgcct gcaccagcgc caacaataac acgtactggt gcatgaggac   3180

catcaatgag actcacaatt tcctcttctg tgaatttgca actggcttcc tagagtactt   3240

tgatctcaac acagacccct accagctgat gaatgcagtg aacacactgg acagggatgt   3300

cctcaaccag ctacacgtac agctcatgga gctgaggagc tgcaagggtt acaagcagtg   3360

taacccccgg actcgaaaca tggacctggg acttaaagat ggaggaagct atgagcaata   3420

caggggacaa ctgtgggaag gctgggaagg ttaagaaaca acagaggtgg acctccaaaa   3480

acatagaggc atcacctgac tgcacaggca atgaaaaacc atgtgggtga tttccagcag   3540

acctgtggta ttggccagga ggcctgagaa agcaagcacg cactctcagt caacatgaca   3600

gattctggag gataaccagc aggagcagag ataacttcag gaagtccatt tttgcccctg   3660

cttttgcttt ggattatacc tcaccagctg cacaaaatgc attttttcgt atcaaaaagt   3720

caccactaac cctcccccag aagctcacaa aggaaaacgg agagagcgag cgagagagat   3780

ttccttggaa atttctccca agggcgaaag tcattggaat ttttaaatca taggggaaaa   3840

gcagtcctgt tctaaatcct cttattcttt tggtttgtca caaagaagga actaagaagc   3900

aggacagagg caacgtggag aggctgaaaa cagtgcagag acgtttgaca atgagtcagt   3960

agcacaaaag agatgacatt tacctagcac tataaaccct ggttgcctct gaagaaactg   4020

ccttcattgt atatatgtga ctatttacat gtaatcaaca tgggaacttt taggggaacc   4080

taataagaaa tcccaatttt caggagtggt ggtgtcaata aacgctctgt ggccagtgta   4140

aaagaaaatc cctcgcagtt gtggacattt ctgttcctgt ccagatacca tttctcctag   4200

tatttctttg ttatgtccca gaactgatgt ttttttttta aggtactgaa aagaaatgaa   4260

gttgatgtat gtcccaagtt ttgatgaaac tgtatttgta aaaaaaattt tgtagtttaa   4320

gtattgtcat acagtgttca aaaccccagc caatgaccag cagttggtat gaagaacctt   4380

tgacattttg taaaaggcca tttcttggg                                     4409


<210>  10192
<211>  852
<212>  PRT
<213>  Homo sapiens

<400>  10192

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gly Gln Leu Trp Glu 
        835                 840                 845


Gly Trp Glu Gly 
    850


<210>  10193
<211>  1392
<212>  DNA
<213>  Homo sapiens

<400>  10193
ctttctgtcc tctggagcac agatgttcat gcctgcatct acctccctca ccataactaa     60

ggtcagcgct gaatgaagcc atcagggtcc tgaaactgat catggtgaca ctggatttta    120

ggcaatctac aaggctatct aggagactta gggcaggttc ccctcataat tcagtctacc    180

cctcataatt cagtctactc tgagtaggga acactatcag catcatggga ttgtgacaaa    240

aaagcataag atggttttct ggtgtgttgg ggttgttttg cctaaactat ctgctcctgt    300

tttgtttttc atttctcctt catttaggac ttaaagatgg aggaagctat gagcaataca    360

ggtatttcgt tttattatta aagcctaaac aaagttctcc tatcttggcc catccttcag    420

tctcatctct gtgagtctgc acctgttatc ttgagaaact gcccttccct ctggtctgcc    480

cgagaccagg atcacccacc aaagataggt gtcacctagg agaccttctt tgtatagttc    540

tttggggact ttttctttct tggtgatggt taacattcat tctcctttga cacttgaaaa    600

cttaggcagt ttcagcgtcg aaagtggcca gaaatgaaga gaccttcttc caaatcactg    660

ggacaactgt gggaaggctg ggaaggttaa gaaacaacag aggtggacct ccaaaaacat    720

agaggcatca cctgactgca caggcaatga aaaaccatgt gggtgatttc cagcagacct    780

gtggtattgg ccaggaggcc tgagaaagca agcacgcact ctcagtcaac atgacagatt    840

ctggaggata accagcagga gcagagataa cttcaggaag tccatttttg cccctgcttt    900

tgctttggat tatacctcac cagctgcaca aaatgcattt tttcgtatca aaaagtcacc    960

actaaccctc ccccagaagc tcacaaagga aaacggagag agcgagcgag agagatttcc   1020

ttggaaattt ctcccaaggg cgaaagtcat tggaattttt aaatcatagg ggaaaagcag   1080

tcctgttcta aatcctctta ttcttttggt ttgtcacaaa gaaggaacta agaagcagga   1140

cagaggcaac gtggagaggc tgaaaacagt gcagagacgt ttgacaatga gtcagtagca   1200

caaaagagat gacatttacc tagcactata aaccctggtt gcctctgaag aaactgcctt   1260

cattgtatat atgtgactat ttacatgtaa tcaacatggg aacttttagg ggaacctaat   1320

aagaaatccc aattttcagg agtggtggtg tcaataaacg ctctgtggcc agtgtaaaag   1380

aaaatccctc gc                                                       1392


<210>  10194
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  10194

Arg Asp Leu Leu Pro Asn His Trp Asp Asn Cys Gly Lys Ala Gly Lys 
1               5                   10                  15


Val Lys Lys Gln Gln Arg Trp Thr Ser Lys Asn Ile Glu Ala Ser Pro 
            20                  25                  30


Asp Cys Thr Gly Asn Glu Lys Pro Cys Gly 
        35                  40


<210>  10195
<211>  3997
<212>  DNA
<213>  Homo sapiens

<400>  10195
ctatgctact cccgggccat ttctggacaa cagctgctat tttcacttga gccgaagtta     60

atttctcggg gagttctcgg gcgcgcacag gcagctcggt ttgccctgcg attgagctgc    120

gggtcgcggc cggcgccggc ctctccaatg gcaaatgtgt gtggctggag gcgagcgcga    180

ggctttcggc aaaggcagtc gagtgtttgc agaccggggc gagtcctgtg aaagcagata    240

aaagaaaaca tttattaacg tgtcattacg aggggagcgc ccggccgggg ctgtcgcact    300

ccccgcggaa catttggctc cctccagctc cgagagagga gaagaagaaa gcggaaaaga    360

ggcagattca cgtcgtttcc agccaagtgg acctgatcga tggccctcct gaatttatca    420

cgatatttga tttattagcg atgccccctg gtttgtgtgt tacgcacaca cacgtgcaca    480

caaggctctg gctcgcttcc ctccctcgtt tccagctcct gggcgaatcc cacatctgtt    540

tcaactctcc gccgagggcg agcaggagcg agagtgtgtc gaatctgcga gtgaagaggg    600

acgagggaaa agaaacaaag ccacagacgc aacttgagac tcccgcatcc caaaagaagc    660

accagatcag caaaaaaaga agatgggccc cccgagcctc gtgctgtgct tgctgtccgc    720

aactgtgttc tccctgctgg gtggaagctc ggccttcctg tcgcaccacc gcctgaaagg    780

caggtttcag agggaccgca ggaacatccg ccccaacatc atcctggtgc tgacggacga    840

ccaggatgtg gagctgggtt ccatgcaggt gatgaacaag acccggcgca tcatggagca    900

gggcggggcg cacttcatca acgccttcgt gaccacaccc atgtgctgcc cctcacgctc    960

ctccatcctc actggcaagt acgtccacaa ccacaacacc tacaccaaca atgagaactg   1020

ctcctcgccc tcctggcagg cacagcacga gagccgcacc tttgccgtgt acctcaatag   1080

cactggctac cggacagctt tcttcgggaa gtatcttaat gaatacaacg gctcctacgt   1140

gccacccggc tggaaggagt gggtcggact ccttaaaaac tcccgctttt ataactacac   1200

gctgtgtcgg aacggggtga aagagaagca cggctccgac tactccaagg attacctcac   1260

agacctcatc accaatgaca gcgtgagctt cttccgcacg tccaagaaga tgtacccgca   1320

caggccagtc ctcatggtca tcagccatgc agccccccac ggccctgagg attcagcccc   1380

acaatattca cgcctcttcc caaacgcatc tcagcacatc acgccgagct acaactacgc   1440

gcccaacccg gacaaacact ggatcatgcg ctacacgggg cccatgaagc ccatccacat   1500

ggaattcacc aacatgctcc agcggaagcg cttgcagacc ctcatgtcgg tggacgactc   1560

catggagacg atttacaaca tgctggttga gacgggcgag ctggacaaca cgtacatcgt   1620

atacaccgcc gaccacggtt accacatcgg ccagtttggc ctggtgaaag ggaaatccat   1680

gccatatgag tttgacatca gggtcccgtt ctacgtgagg ggccccaacg tggaagccgg   1740

ctgtctgaat ccccacatcg tcctcaacat tgacctggcc cccaccatcc tggacattgc   1800

aggcctggac atacctgcgg atatggacgg gaaatccatc ctcaagctgc tggacacgga   1860

gcggccggtg aatcggtttc acttgaaaaa gaagatgagg gtctggcggg actccttctt   1920

ggtggagaga ggcaagctgc tacacaagag agacaatgac aaggtggacg cccaggagga   1980

gaactttctg cccaagtacc agcgtgtgaa ggacctgtgt cagcgtgctg agtaccagac   2040

ggcgtgtgag cagctgggac agaagtggca gtgtgtggag gacgccacgg ggaagctgaa   2100

gctgcataag tgcaagggcc ccatgcggct gggcggcagc agagccctct ccaacctcgt   2160

gcccaagtac tacgggcagg gcagcgaggc ctgcacctgt gacagcgggg actacaagct   2220

cagcctggcc ggacgccgga aaaaactctt caagaagaag tacaaggcca gctatgtccg   2280

cagtcgctcc atccgctcag tggccatcga ggtggacggc agggtgtacc acgtaggcct   2340

gggtgatgcc gcccagcccc gaaacctcac caagcggcac tggccagggg cccctgagga   2400

ccaagatgac aaggatggtg gggacttcag tggcactgga ggccttcccg actactcagc   2460

cgccaacccc attaaagtga cacatcggtg ctacatccta gagaacgaca cagtccagtg   2520

tgacctggac ctgtacaagt ccctgcaggc ctggaaagac cacaagctgc acatcgacca   2580

cgagattgaa accctgcaga acaaaattaa gaacctgagg gaagtccgag gtcacctgaa   2640

gaaaaagcgg ccagaagaat gtgactgtca caaaatcagc taccacaccc agcacaaagg   2700

ccgcctcaag cacagaggct ccagtctgca tcctttcagg aagggcctgc aagagaagga   2760

caaggtgtgg ctgttgcggg agcagaagcg caagaagaaa ctccgcaagc tgctcaagcg   2820

cctgcagaac aacgacacgt gcagcatgcc aggcctcacg tgcttcaccc acgacaacca   2880

gcactggcag acggcgcctt tctggacact ggggcctttc tgtgcctgca ccagcgccaa   2940

caataacacg tactggtgca tgaggaccat caatgagact cacaatttcc tcttctgtga   3000

atttgcaact ggcttcctag agtactttga tctcaacaca gacccctacc agctgatgaa   3060

tgcagtgaac acactggaca gggatgtcct caaccagcta cacgtacagc tcatggagct   3120

gaggagctgc aagggttaca agcagtgtaa cccccggact cgaaacatgg acctgggact   3180

taaagatgga ggaagctatg agcaatacag gcagtttcag cgtcgaaagt ggccagaaat   3240

gaagagacct tcttccaaat cactgggaca actgtgggaa ggctgggaag gttaagaaac   3300

aacagaggtg gacctccaaa aacatagagg catcacctga ctgcacaggc aatgaaaaac   3360

catgtgggtg atttccagca gacctgtggt attggccagg aggcctgaga aagcaagcac   3420

gcactctcag tcaacatgac agattctgga ggataaccag caggagcaga gataacttca   3480

ggaagtccat ttttgcccct gcttttgctt tggattatac ctcaccagct gcacaaaatg   3540

cattttttcg tatcaaaaag tcaccactaa ccctccccca gaagctcaca aaggaaaacg   3600

gagagagcga gcgagagaga tttccttgga aatttctccc aagggcgaaa gtcattggaa   3660

tttttaaatc ataggggaaa agcagtcctg ttctaaatcc tcttattctt ttggtttgtc   3720

acaaagaagg aactaagaag caggacagag gcaacgtgga gaggctgaaa acagtgcaga   3780

gacgtttgac aatgagtcag tagcacaaaa gagatgacat ttacctagca ctataaaccc   3840

tggttgcctc tgaagaaact gccttcattg tatatatgtg actatttaca tgtaatcaac   3900

atgggaactt ttaggggaac ctaataagaa atcccaattt tcaggagtgg tggtgtcaat   3960

aaacgctctg tggccagtgt aaaagaaaat ccctcgc                            3997


<210>  10196
<211>  870
<212>  PRT
<213>  Homo sapiens

<400>  10196

Met Gly Pro Pro Ser Leu Val Leu Cys Leu Leu Ser Ala Thr Val Phe 
1               5                   10                  15


Ser Leu Leu Gly Gly Ser Ser Ala Phe Leu Ser His His Arg Leu Lys 
            20                  25                  30


Gly Arg Phe Gln Arg Asp Arg Arg Asn Ile Arg Pro Asn Ile Ile Leu 
        35                  40                  45


Val Leu Thr Asp Asp Gln Asp Val Glu Leu Gly Ser Met Gln Val Met 
    50                  55                  60


Asn Lys Thr Arg Arg Ile Met Glu Gln Gly Gly Ala His Phe Ile Asn 
65                  70                  75                  80


Ala Phe Val Thr Thr Pro Met Cys Cys Pro Ser Arg Ser Ser Ile Leu 
                85                  90                  95


Thr Gly Lys Tyr Val His Asn His Asn Thr Tyr Thr Asn Asn Glu Asn 
            100                 105                 110


Cys Ser Ser Pro Ser Trp Gln Ala Gln His Glu Ser Arg Thr Phe Ala 
        115                 120                 125


Val Tyr Leu Asn Ser Thr Gly Tyr Arg Thr Ala Phe Phe Gly Lys Tyr 
    130                 135                 140


Leu Asn Glu Tyr Asn Gly Ser Tyr Val Pro Pro Gly Trp Lys Glu Trp 
145                 150                 155                 160


Val Gly Leu Leu Lys Asn Ser Arg Phe Tyr Asn Tyr Thr Leu Cys Arg 
                165                 170                 175


Asn Gly Val Lys Glu Lys His Gly Ser Asp Tyr Ser Lys Asp Tyr Leu 
            180                 185                 190


Thr Asp Leu Ile Thr Asn Asp Ser Val Ser Phe Phe Arg Thr Ser Lys 
        195                 200                 205


Lys Met Tyr Pro His Arg Pro Val Leu Met Val Ile Ser His Ala Ala 
    210                 215                 220


Pro His Gly Pro Glu Asp Ser Ala Pro Gln Tyr Ser Arg Leu Phe Pro 
225                 230                 235                 240


Asn Ala Ser Gln His Ile Thr Pro Ser Tyr Asn Tyr Ala Pro Asn Pro 
                245                 250                 255


Asp Lys His Trp Ile Met Arg Tyr Thr Gly Pro Met Lys Pro Ile His 
            260                 265                 270


Met Glu Phe Thr Asn Met Leu Gln Arg Lys Arg Leu Gln Thr Leu Met 
        275                 280                 285


Ser Val Asp Asp Ser Met Glu Thr Ile Tyr Asn Met Leu Val Glu Thr 
    290                 295                 300


Gly Glu Leu Asp Asn Thr Tyr Ile Val Tyr Thr Ala Asp His Gly Tyr 
305                 310                 315                 320


His Ile Gly Gln Phe Gly Leu Val Lys Gly Lys Ser Met Pro Tyr Glu 
                325                 330                 335


Phe Asp Ile Arg Val Pro Phe Tyr Val Arg Gly Pro Asn Val Glu Ala 
            340                 345                 350


Gly Cys Leu Asn Pro His Ile Val Leu Asn Ile Asp Leu Ala Pro Thr 
        355                 360                 365


Ile Leu Asp Ile Ala Gly Leu Asp Ile Pro Ala Asp Met Asp Gly Lys 
    370                 375                 380


Ser Ile Leu Lys Leu Leu Asp Thr Glu Arg Pro Val Asn Arg Phe His 
385                 390                 395                 400


Leu Lys Lys Lys Met Arg Val Trp Arg Asp Ser Phe Leu Val Glu Arg 
                405                 410                 415


Gly Lys Leu Leu His Lys Arg Asp Asn Asp Lys Val Asp Ala Gln Glu 
            420                 425                 430


Glu Asn Phe Leu Pro Lys Tyr Gln Arg Val Lys Asp Leu Cys Gln Arg 
        435                 440                 445


Ala Glu Tyr Gln Thr Ala Cys Glu Gln Leu Gly Gln Lys Trp Gln Cys 
    450                 455                 460


Val Glu Asp Ala Thr Gly Lys Leu Lys Leu His Lys Cys Lys Gly Pro 
465                 470                 475                 480


Met Arg Leu Gly Gly Ser Arg Ala Leu Ser Asn Leu Val Pro Lys Tyr 
                485                 490                 495


Tyr Gly Gln Gly Ser Glu Ala Cys Thr Cys Asp Ser Gly Asp Tyr Lys 
            500                 505                 510


Leu Ser Leu Ala Gly Arg Arg Lys Lys Leu Phe Lys Lys Lys Tyr Lys 
        515                 520                 525


Ala Ser Tyr Val Arg Ser Arg Ser Ile Arg Ser Val Ala Ile Glu Val 
    530                 535                 540


Asp Gly Arg Val Tyr His Val Gly Leu Gly Asp Ala Ala Gln Pro Arg 
545                 550                 555                 560


Asn Leu Thr Lys Arg His Trp Pro Gly Ala Pro Glu Asp Gln Asp Asp 
                565                 570                 575


Lys Asp Gly Gly Asp Phe Ser Gly Thr Gly Gly Leu Pro Asp Tyr Ser 
            580                 585                 590


Ala Ala Asn Pro Ile Lys Val Thr His Arg Cys Tyr Ile Leu Glu Asn 
        595                 600                 605


Asp Thr Val Gln Cys Asp Leu Asp Leu Tyr Lys Ser Leu Gln Ala Trp 
    610                 615                 620


Lys Asp His Lys Leu His Ile Asp His Glu Ile Glu Thr Leu Gln Asn 
625                 630                 635                 640


Lys Ile Lys Asn Leu Arg Glu Val Arg Gly His Leu Lys Lys Lys Arg 
                645                 650                 655


Pro Glu Glu Cys Asp Cys His Lys Ile Ser Tyr His Thr Gln His Lys 
            660                 665                 670


Gly Arg Leu Lys His Arg Gly Ser Ser Leu His Pro Phe Arg Lys Gly 
        675                 680                 685


Leu Gln Glu Lys Asp Lys Val Trp Leu Leu Arg Glu Gln Lys Arg Lys 
    690                 695                 700


Lys Lys Leu Arg Lys Leu Leu Lys Arg Leu Gln Asn Asn Asp Thr Cys 
705                 710                 715                 720


Ser Met Pro Gly Leu Thr Cys Phe Thr His Asp Asn Gln His Trp Gln 
                725                 730                 735


Thr Ala Pro Phe Trp Thr Leu Gly Pro Phe Cys Ala Cys Thr Ser Ala 
            740                 745                 750


Asn Asn Asn Thr Tyr Trp Cys Met Arg Thr Ile Asn Glu Thr His Asn 
        755                 760                 765


Phe Leu Phe Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Leu 
    770                 775                 780


Asn Thr Asp Pro Tyr Gln Leu Met Asn Ala Val Asn Thr Leu Asp Arg 
785                 790                 795                 800


Asp Val Leu Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys 
                805                 810                 815


Lys Gly Tyr Lys Gln Cys Asn Pro Arg Thr Arg Asn Met Asp Leu Gly 
            820                 825                 830


Leu Lys Asp Gly Gly Ser Tyr Glu Gln Tyr Arg Gln Phe Gln Arg Arg 
        835                 840                 845


Lys Trp Pro Glu Met Lys Arg Pro Ser Ser Lys Ser Leu Gly Gln Leu 
    850                 855                 860


Trp Glu Gly Trp Glu Gly 
865                 870


<210>  10197
<211>  365
<212>  DNA
<213>  Homo sapiens

<400>  10197
gaatcaaaca atacggcctg ggtggtattt atggagcatc tgctgtatat cctgggcagt     60

gttctgggcc acgagaatga agtcatcaac aggtcgttgt ccttataaga aggacaaccc    120

tgtggggatt ctacaactca ttcttcagac aaaccttctg gaagcctacc tacttttatt    180

ctggtgtttg ccctggtagc aatttaactg tcactttaag aagacgcgaa tggggttggt    240

gtctctggct tttgagactt cagggcaccc ctttcttgga gagaaagata ctcctttatc    300

aggccagaga gctgaagacc tgttgggctt ggggccactc cctttaataa agaaacccac    360

atcct                                                                365


<210>  10198
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10198

Met Gly Leu Val Ser Leu Ala Phe Glu Thr Ser Gly His Pro Phe Leu 
1               5                   10                  15


Gly Glu Lys Asp Thr Pro Leu Ser Gly Gln Arg Ala Glu Asp Leu Leu 
            20                  25                  30


Gly Leu Gly Pro Leu Pro Leu Ile Lys Lys Pro Thr 
        35                  40


<210>  10199
<211>  9029
<212>  DNA
<213>  Homo sapiens

<400>  10199
gtgacgcgct ccaacatggc ggcgccgtgg ggccgaggtg tcgcttcctg acggggcggc     60

gcggacggac gcggccggtg ccggccggga cgccgggccc gcagcctagc tcgccatctc    120

gctcacgccg cccgcccgcg gggccgtcag cccccgccgg gccggggcca tgcaggagag    180

ccagaccaag agcatgttcg tgtcccgggc cctggagaag atcctagccg acaaggaggt    240

gaagcggccc cagcactccc agctgcgcag ggcctgccag gtggcgctcg atgaaattaa    300

agcagaaata gaaaagcaga ggcttggcac tgctgcacca ccaaaggcaa acttcattga    360

agctgacaag tattttcttc cattcgagct agcttgccag tccaagtccc caagggtagt    420

cagcacatcc cttgactgct tgcagaaact catcgcatac gggcacatca ctggcaacgc    480

ccctgacagt ggagcccctg ggaagcggct gatcgacaga attgttgaaa ccatttgcag    540

ttgttttcag ggccctcaga ctgatgaagg ggttcagtta caaataatta aggctcttct    600

gactgcagtg acttccccac acattgaaat tcatgagggt actatcctgc agacagtgag    660

aacatgttac aatatctatt tggccagcaa aaatctcatc aatcaaacca ctgccaaggc    720

tacccttact cagatgctga acgtcatttt cacccgcatg gaaaaccaag tgttgcagga    780

ggccagagaa ctggaaaaac caatccagtc aaaaccccag tcccctgtga tccaagctgc    840

agcagtatcc ccaaagttcg ttcgtttgaa gcacagtcag gcacaaagca aaccaacaac    900

tcccgaaaaa acagatttaa ccaacggtga acatgccagg agtgattctg gaaaagtaag    960

cacagaaaat ggagacgcac ccagagaaag aggctcatca ctgtcaggga ctgatgacgg   1020

agcccaggag gtggtgaagg acatcttgga agatgtagtc acatctgcca ttaaagaagc   1080

agcggaaaag catggtctga cagaacctga gagagttcta ggtgaactgg agtgccagga   1140

atgtgctatt cccccaggag ttgatgaaaa ctcacagacc aacgggatag ccgatgacag   1200

gcagtccttg tcgtcagcag ataatctgga atcggatgca caaggacatc aagtggctgc   1260

caggttctcc cacgttctgc agaaggatgc cttccttgtg ttccgctccc tgtgcaagct   1320

gtccatgaaa ccccttggtg aaggccctcc agacccaaaa tcccatgagc tgcgttccaa   1380

ggtggtttcc ctgcagctgc tcctctctgt gttgcaaaat gctggccccg tattcaggac   1440

tcacgagatg ttcatcaatg caatcaagca atatctctgt gtggccttgt ccaaaaacgg   1500

cgtctcttca gtgcctgatg tctttgagct ctctcttgcc atttttctta ctcttctttc   1560

aaactttaaa atgcacttga aaatgcagat agaggtcttt ttcaaagaga ttttcctgaa   1620

cattttagaa acatcaacaa gttcttttga gcacaggtgg atggtcattc agactctgac   1680

gaggatctgt gcagatgccc agtgtgttgt ggatatttat gtcaactacg actgtgattt   1740

aaatgctgct aacatttttg agcgccttgt aaatgattta tccaaaattg ctcagggaag   1800

aagtggacat gagctgggaa tgacacctct gcaggagctc agcctgagga agaaaggcct   1860

ggagtgcctc gtgtccattc tcaagtgcat ggtggagtgg agcaaagacc tgtatgtgaa   1920

tcccaaccac cagaccagcc tcggtcagga gaggctcacg gatcaggaaa taggggatgg   1980

gaaaggcctt gacatggcaa gacggtgtag tgtgacgtcc atggagtcca cagtgtcctc   2040

ggggacccag acaactgttc aggatgaccc tgagcaattt gaggtcatca agcaacaaaa   2100

agaaatcatt gaacacggca tcgagctgtt caacaagaaa cccaagaggg ggatccagtt   2160

tctccaggag cagggcatgc tgggaacgtc agttgaagac atagcccaat tcctgcacca   2220

ggaggagcgc ctggattcca cccaagtagg cgattttctg ggagatagcg caaggttcaa   2280

caaggaggtg atgtatgcct acgtggacca acttgacttc tgtgaaaaag aatttgtctc   2340

agccctgcgg acattcctag aaggtttccg cctacctgga gaagcccaaa agattgaccg   2400

attaatggag aagtttgccg caagatacat agaatgcaac caagggcaaa ctctgtttgc   2460

tagtgctgac actgcttatg tcctagcgta ttcaattatt atgctgacta cagacttgca   2520

cagtcctcag gtaaaaaata aaatgacgaa agagcagtat attaaaatga atcggggtat   2580

caatgatagt aaagatctgc cagaagagta tctctcaagc atctatgaag agatagaagg   2640

caagaaaatt gcaatgaaag aaacaaaaga gctaacgatt gcaaccaaat ctactaagca   2700

gaatgtagct agtgaaaagc agcggcggct gctgtacaac ttagagatgg agcaaatggc   2760

taaaacagcc aaagctctga tggaggctgt gagccatgcc aaagccccgt ttaccagtgc   2820

cactcacctg gaccatgtcc ggccaatgtt caaactggtg tggacgccac tattggcagc   2880

ctacagcatc ggactccaga actgtgatga cactgaagtg gcctccttgt gtttggaagg   2940

catccgatgt gcaatccgaa tcgcctgcat ctttggaatg cagctggaac gagatgccta   3000

tgttcaggct cttgctcgct tctccctact cacagccagc tccagcatca cagaaatgaa   3060

gcagaaaaac atcgacacca ttaagacgct tatcacagtg gctcacaccg atggcaacta   3120

ccttgggaat tcctggcatg agatcttgaa atgcatcagc cagctggagc tcgctcagct   3180

gataggaacc ggtgtgaaga cgcgctacct gtctggatct gggcgtgaaa gagaagggag   3240

cctgaagggc cacacattgg caggagaaga gttcatgggc cttggcctcg gtaatttggt   3300

gagtggcgga gtggataaaa gacagatggc cagcttccaa gaatcggttg gtgagaccag   3360

ctcgcagagt gtggttgtag ctgtggacag gatttttact gggtctacca gactggatgg   3420

aaatgcaata gttgactttg tccgctggct gtgtgctgtg tccatggatg aactggcttc   3480

cccccaccat cctcgcatgt tcagcttgca gaagattgtg gagatatcat actacaacat   3540

gaatcggatc cgactacagt ggtctcgaat atggcatgtg attggagatc acttcaataa   3600

ggttggctgc aaccctaatg aagatgtggc tatctttgct gttgactcat taaggcaact   3660

ctccatgaag tttcttgaga agggtgaatt agccaacttc cgtttccaga aagattttct   3720

gaggcccttt gagcatatta tgaagaaaaa caggtctccc accatccggg acatggcgat   3780

ccgctgcatt gcccagatgg tgaactccca ggcggccaac atccgctcag gttggaagaa   3840

catctttgcc gtgttccacc aggcagcctc tgatcatgat gggaacattg tggagctggc   3900

cttccagacc acttgccaca ttgtcacaac tattttccag caccattttc ctgcagccat   3960

cgattccttt caggatgctg tgaagtgctt atcagagttc gcctgcaacg ccgctttccc   4020

tgacacgagc atggaagcga ttcggctcat ccgcttctgt ggcaaatacg tctctgagag   4080

gcctcgggtg ctacaagaat acacaagtga tgacatgaat gtagctcctg gtgacagagt   4140

ctgggtccga ggctggttcc ccatcttatt cgaactctcc tgcatcatta atagatgcaa   4200

gttagatgta cgaacaaggg gactcacagt catgtttgag atcatgaaga gctatggcca   4260

cacctttgaa aagcactggt ggcaggacct gttcagaatc gtgtttcgga tttttgacaa   4320

tatgaaactc cctgagcaac tgtcagagaa atctgagtgg atgacaacaa cctgcaatca   4380

cgcactttat gctatttgtg atgtttttac ccagttttat gaagctttga atgaagttct   4440

tctttctgat gtatttgcac aattgcagtg gtgtgtcaaa caagataatg aacagttggc   4500

gcgatcaggt acaaattgct tagaaaactt agtaatatcc aatggagaga aattcagtcc   4560

tgaagtctgg gatgaaacct gcaactgtat gttggatatt ttcaaaacaa ccatcccaca   4620

tgttttgctg acatggagac ctgtaggaat ggaggaagat tcatcagaaa agcatttgga   4680

tgtggatctg gaccgccagt ctttaagcag catagataaa aatccctctg agaggggaca   4740

gagccagctc tctaacccaa cagatgacag ctggaagggt agaccatacg caaatcagaa   4800

actgtttgcc agcctcctca tcaagtgtgt ggtccagttg gaattgatac agaccattga   4860

caacattgtg ttctaccctg cgacgagcaa aaaggaggat gcagagcaca tggttgccgc   4920

ccagcaagac acgctggatg cagatatcca catagagacg gaggatcagg gcatgtataa   4980

gtacatgtct tcccagcacc tcttcaagct gttggactgt ttgcaggaat cccattcatt   5040

ctcaaaggcc ttcaactcca attacgagca gcggactgtc ctgtggcgag caggttttaa   5100

gggcaagtct aaacccaatc ttctaaaaca agaaaccagc agcctggcct gttgtttgag   5160

gatcctgttt cgaatgtatg ttgatgagaa ccgcagggat tcctgggaag aaatacagca   5220

gagactttta actgtttgca gtgaagctct tgcctatttc atcactgtga attctgagag   5280

ccatcgggag gcctggacaa gtctcttgtt gttacttcta actaaaaccc tcaaaataaa   5340

tgatgaaaag ttcaaagcac atgcttcaat gtactacccc tacttgtgtg aaattatgca   5400

gtttgacctg atccctgagc tccgagcagt tctgcggaag ttcttcctac ggataggtgt   5460

tgtgtataag atatggatac cagaagagcc atcacaggta ccagcagcac tgtcaccagt   5520

gtggtagccc tggctgccca ggccagtgct gcagctctgc agaatgttca gcatgccatt   5580

tctgactggc acatctcgtg aagtttcata gaaacaagga gttggcatct tggatctcag   5640

aatggcctgg aaacggatgg cctctacgct gttccatcac agtctccaac taaggcttat   5700

ggtatttcat taaactgttg catacccagt tagcacagta ggtggggagt ctgcttcatt   5760

tctatcattc catttttctg attaaactgt caaatctgtc attgcatatg ccatcgtttt   5820

ctagcaaaat cccatgattg gctataaacg ttttgtaaga agtcactctc cttgaaaata   5880

ctgaacatag ctgtataggt ttgtgattat tagagaatat gttaataaaa cttcttgtaa   5940

cggctaactg ccacctaaaa tatgctgggt tttctgttgt ttgagtgtgt tagagaaatt   6000

tgaatgtttt tgtcagttac gagtcagccg taattagatt agtttaagga caggtcagga   6060

ttagagaaga gttgtttttg tgttttgtta atgtctgagt gatttttaaa gtattttaca   6120

aaaagatatt gaaaatttgg ttgaaggcag agtttagtaa ttaagttaga attaagagtt   6180

ttgcgaggtt aaaaaaatgt gcctcgtgga tctccctgtt ttagtaacat ggagagaaaa   6240

agtctacacg aaaaagtgaa caatttaatg aagatgatta gccttccttg aaataagtat   6300

ttgtggatgg gtgttaaatt aaaatttcca gaatacactg tccatctcac acactctgaa   6360

atctaatata tgaagtagta atgaaaatga agtagtaatt taaccagagt tcatttatcc   6420

ttgaataaac ctttttattt tcacctcaga aaagtgagtg tactggcagt tagtgtcact   6480

gctttgcaca gtccccatta aaggaccctc cagagaggga cagtaactgt gcatgagaag   6540

ccgctcccat aagcctcctc agccagatgt catgggtgga actggagctg tgtcggggcc   6600

agcacagctg aactgtgaca atggcaggag gtggcatgtg cccagcactt ccattaatct   6660

gagcctagga gttgaattct ttggcaaggt tggattctga ggtccttatt atgttaatga   6720

tggtgcaata ctctcacctg cagtagaact gagttctgct gcagcttgtg taaaagtggg   6780

cagtacacaa gtacgtccca aagcctgtga gcagtatacg tggatgctca cccatgagaa   6840

ggagcacaca cgcctcattc tctgccctca cccactgctc acctagagca tcgctgagcg   6900

ttagacaaag tgttacacag aatgattaaa actttcagac ttctacctat gctctttagt   6960

cctgtaaatt gggttgtatt gatgtcaact ctggtgcctt agaagttagt agtttgggaa   7020

cctatctgta aaatcagatg ttttttcttt gtagagaagg atttctggtg cttttgctta   7080

ctaagagacc gatattctta agttgttttc ttgttttaac agccttgaga aatgtttggt   7140

tttggccagc agaattcttg tctacttttt tctttcccaa aaagtgtttt ttaatttctc   7200

taccaaagaa aaaatgagca ggtttaggtt tttacatgac ttatatacat tagataaaag   7260

gagctgtata atttagcagg aagggactat gggagaatac tttactgtga gtggaaaatg   7320

ttagcacatt tgactggttt gccctggaat ccactgcacc tttacactgc accatgaaac   7380

ctacactccc tggtatcata gcgcgtcatc acctcaacaa gtcagtcgtc tccattgata   7440

tttgtacaaa aggtatacat ggggaacacg tgttcattca ttaagtccat cttgcgtgca   7500

gctatatccc tgattggtta tttttccttt ccttctgagg ttctcatgtc attttcttca   7560

tcggatgtga ctaaaatttt tctggtgtct tctgccctct ctttaatttt gcctcttgag   7620

gggtagcaga tgtgtcagtg cattttatta cttgctgaaa cattcaggct tacatttctt   7680

attagtttag tattttaaaa gatttaattt tctgaatgag gcatttgaat tgtaccagca   7740

atggactttt aaaaaattgg atgtaaaacc attcagggtg atttttcttg tcagtggaca   7800

gtgacgaaca gagatttgaa atcccttacc tccaataata agccattcag cctaaattca   7860

tttttatgaa taaatctctt ctttctcatg gtaaatgtgg cttgtgccac tcaaacacta   7920

gtgaaagggt atgtacaacc gcaacatcag gccaggacac catttattta accaagtaat   7980

ggaggagagt gaaacatttt ccaaggcctt atttcttttt cagaatgctt taagtgttga   8040

ttatatgtgc tgggtctcta gagaagtttt tatttgttac aatactgctg ctttgagcaa   8100

ttttgtttct cttcattgtc tgttagggaa atcaccagct ttggcatctt aacaacaaac   8160

agtggatggg taatttttat ttctgatacg catctttaga gtcaaatata tcttttccct   8220

gtactcctca tgtacaacca aagaacatac attatgaaaa ttgtattata atatctggaa   8280

acacaacatt ttcctctggc aggtgacttt tgtacgaaat gaaaaaaaaa aaacctgtat   8340

tttttttgtt gttcttttgt gattaaggat atacatttag tagtctttgt tattaaagga   8400

acctgctgat aagtacaagt gtgaccatct cattcaaatg tttgttgtta tgatgcaaat   8460

ggatattggt ttcaatagaa gctggatcct taatactgca ttttctgaat tctgttttaa   8520

tatttgtgtt aaagtagaca tagctgaact cacatggaat cctggagttt tgttatcagc   8580

agctttgcag tttgggaaac aaagaaacca aagctgagtg ttttaaagaa tgaacatatc   8640

tggaaatcct tgctctcaaa acaaaacaat ataatctatc aaaggtgttt tactcagtgt   8700

tctaattttt aaaaaatttt atctgcatat ttgcatcaaa tatttatgtg taaaatgtat   8760

gttttacctc cttaaaatgc ctaaaagtta gttaatagtt actttggttt aacctataca   8820

caatgattaa gtgcatttaa tattggtaat ttaatgaaaa ccattccttg cccaatggat   8880

gtataaattt ttgaaagaat aagcagaatt atataatatg aaatgctatg taaagttttc   8940

tatgtaaaaa tattatgtat aatactatta aaatatccca tgctttgatc aggtggtaca   9000

tcaataaaat tttaaaaagt atagctgtt                                     9029


<210>  10200
<211>  1785
<212>  PRT
<213>  Homo sapiens

<400>  10200

Met Gln Glu Ser Gln Thr Lys Ser Met Phe Val Ser Arg Ala Leu Glu 
1               5                   10                  15


Lys Ile Leu Ala Asp Lys Glu Val Lys Arg Pro Gln His Ser Gln Leu 
            20                  25                  30


Arg Arg Ala Cys Gln Val Ala Leu Asp Glu Ile Lys Ala Glu Ile Glu 
        35                  40                  45


Lys Gln Arg Leu Gly Thr Ala Ala Pro Pro Lys Ala Asn Phe Ile Glu 
    50                  55                  60


Ala Asp Lys Tyr Phe Leu Pro Phe Glu Leu Ala Cys Gln Ser Lys Ser 
65                  70                  75                  80


Pro Arg Val Val Ser Thr Ser Leu Asp Cys Leu Gln Lys Leu Ile Ala 
                85                  90                  95


Tyr Gly His Ile Thr Gly Asn Ala Pro Asp Ser Gly Ala Pro Gly Lys 
            100                 105                 110


Arg Leu Ile Asp Arg Ile Val Glu Thr Ile Cys Ser Cys Phe Gln Gly 
        115                 120                 125


Pro Gln Thr Asp Glu Gly Val Gln Leu Gln Ile Ile Lys Ala Leu Leu 
    130                 135                 140


Thr Ala Val Thr Ser Pro His Ile Glu Ile His Glu Gly Thr Ile Leu 
145                 150                 155                 160


Gln Thr Val Arg Thr Cys Tyr Asn Ile Tyr Leu Ala Ser Lys Asn Leu 
                165                 170                 175


Ile Asn Gln Thr Thr Ala Lys Ala Thr Leu Thr Gln Met Leu Asn Val 
            180                 185                 190


Ile Phe Thr Arg Met Glu Asn Gln Val Leu Gln Glu Ala Arg Glu Leu 
        195                 200                 205


Glu Lys Pro Ile Gln Ser Lys Pro Gln Ser Pro Val Ile Gln Ala Ala 
    210                 215                 220


Ala Val Ser Pro Lys Phe Val Arg Leu Lys His Ser Gln Ala Gln Ser 
225                 230                 235                 240


Lys Pro Thr Thr Pro Glu Lys Thr Asp Leu Thr Asn Gly Glu His Ala 
                245                 250                 255


Arg Ser Asp Ser Gly Lys Val Ser Thr Glu Asn Gly Asp Ala Pro Arg 
            260                 265                 270


Glu Arg Gly Ser Ser Leu Ser Gly Thr Asp Asp Gly Ala Gln Glu Val 
        275                 280                 285


Val Lys Asp Ile Leu Glu Asp Val Val Thr Ser Ala Ile Lys Glu Ala 
    290                 295                 300


Ala Glu Lys His Gly Leu Thr Glu Pro Glu Arg Val Leu Gly Glu Leu 
305                 310                 315                 320


Glu Cys Gln Glu Cys Ala Ile Pro Pro Gly Val Asp Glu Asn Ser Gln 
                325                 330                 335


Thr Asn Gly Ile Ala Asp Asp Arg Gln Ser Leu Ser Ser Ala Asp Asn 
            340                 345                 350


Leu Glu Ser Asp Ala Gln Gly His Gln Val Ala Ala Arg Phe Ser His 
        355                 360                 365


Val Leu Gln Lys Asp Ala Phe Leu Val Phe Arg Ser Leu Cys Lys Leu 
    370                 375                 380


Ser Met Lys Pro Leu Gly Glu Gly Pro Pro Asp Pro Lys Ser His Glu 
385                 390                 395                 400


Leu Arg Ser Lys Val Val Ser Leu Gln Leu Leu Leu Ser Val Leu Gln 
                405                 410                 415


Asn Ala Gly Pro Val Phe Arg Thr His Glu Met Phe Ile Asn Ala Ile 
            420                 425                 430


Lys Gln Tyr Leu Cys Val Ala Leu Ser Lys Asn Gly Val Ser Ser Val 
        435                 440                 445


Pro Asp Val Phe Glu Leu Ser Leu Ala Ile Phe Leu Thr Leu Leu Ser 
    450                 455                 460


Asn Phe Lys Met His Leu Lys Met Gln Ile Glu Val Phe Phe Lys Glu 
465                 470                 475                 480


Ile Phe Leu Asn Ile Leu Glu Thr Ser Thr Ser Ser Phe Glu His Arg 
                485                 490                 495


Trp Met Val Ile Gln Thr Leu Thr Arg Ile Cys Ala Asp Ala Gln Cys 
            500                 505                 510


Val Val Asp Ile Tyr Val Asn Tyr Asp Cys Asp Leu Asn Ala Ala Asn 
        515                 520                 525


Ile Phe Glu Arg Leu Val Asn Asp Leu Ser Lys Ile Ala Gln Gly Arg 
    530                 535                 540


Ser Gly His Glu Leu Gly Met Thr Pro Leu Gln Glu Leu Ser Leu Arg 
545                 550                 555                 560


Lys Lys Gly Leu Glu Cys Leu Val Ser Ile Leu Lys Cys Met Val Glu 
                565                 570                 575


Trp Ser Lys Asp Leu Tyr Val Asn Pro Asn His Gln Thr Ser Leu Gly 
            580                 585                 590


Gln Glu Arg Leu Thr Asp Gln Glu Ile Gly Asp Gly Lys Gly Leu Asp 
        595                 600                 605


Met Ala Arg Arg Cys Ser Val Thr Ser Met Glu Ser Thr Val Ser Ser 
    610                 615                 620


Gly Thr Gln Thr Thr Val Gln Asp Asp Pro Glu Gln Phe Glu Val Ile 
625                 630                 635                 640


Lys Gln Gln Lys Glu Ile Ile Glu His Gly Ile Glu Leu Phe Asn Lys 
                645                 650                 655


Lys Pro Lys Arg Gly Ile Gln Phe Leu Gln Glu Gln Gly Met Leu Gly 
            660                 665                 670


Thr Ser Val Glu Asp Ile Ala Gln Phe Leu His Gln Glu Glu Arg Leu 
        675                 680                 685


Asp Ser Thr Gln Val Gly Asp Phe Leu Gly Asp Ser Ala Arg Phe Asn 
    690                 695                 700


Lys Glu Val Met Tyr Ala Tyr Val Asp Gln Leu Asp Phe Cys Glu Lys 
705                 710                 715                 720


Glu Phe Val Ser Ala Leu Arg Thr Phe Leu Glu Gly Phe Arg Leu Pro 
                725                 730                 735


Gly Glu Ala Gln Lys Ile Asp Arg Leu Met Glu Lys Phe Ala Ala Arg 
            740                 745                 750


Tyr Ile Glu Cys Asn Gln Gly Gln Thr Leu Phe Ala Ser Ala Asp Thr 
        755                 760                 765


Ala Tyr Val Leu Ala Tyr Ser Ile Ile Met Leu Thr Thr Asp Leu His 
    770                 775                 780


Ser Pro Gln Val Lys Asn Lys Met Thr Lys Glu Gln Tyr Ile Lys Met 
785                 790                 795                 800


Asn Arg Gly Ile Asn Asp Ser Lys Asp Leu Pro Glu Glu Tyr Leu Ser 
                805                 810                 815


Ser Ile Tyr Glu Glu Ile Glu Gly Lys Lys Ile Ala Met Lys Glu Thr 
            820                 825                 830


Lys Glu Leu Thr Ile Ala Thr Lys Ser Thr Lys Gln Asn Val Ala Ser 
        835                 840                 845


Glu Lys Gln Arg Arg Leu Leu Tyr Asn Leu Glu Met Glu Gln Met Ala 
    850                 855                 860


Lys Thr Ala Lys Ala Leu Met Glu Ala Val Ser His Ala Lys Ala Pro 
865                 870                 875                 880


Phe Thr Ser Ala Thr His Leu Asp His Val Arg Pro Met Phe Lys Leu 
                885                 890                 895


Val Trp Thr Pro Leu Leu Ala Ala Tyr Ser Ile Gly Leu Gln Asn Cys 
            900                 905                 910


Asp Asp Thr Glu Val Ala Ser Leu Cys Leu Glu Gly Ile Arg Cys Ala 
        915                 920                 925


Ile Arg Ile Ala Cys Ile Phe Gly Met Gln Leu Glu Arg Asp Ala Tyr 
    930                 935                 940


Val Gln Ala Leu Ala Arg Phe Ser Leu Leu Thr Ala Ser Ser Ser Ile 
945                 950                 955                 960


Thr Glu Met Lys Gln Lys Asn Ile Asp Thr Ile Lys Thr Leu Ile Thr 
                965                 970                 975


Val Ala His Thr Asp Gly Asn Tyr Leu Gly Asn Ser Trp His Glu Ile 
            980                 985                 990


Leu Lys Cys Ile Ser Gln Leu Glu Leu Ala Gln Leu Ile Gly Thr Gly 
        995                 1000                1005


Val Lys Thr Arg Tyr Leu Ser Gly Ser Gly Arg Glu Arg Glu Gly Ser 
    1010                1015                1020


Leu Lys Gly His Thr Leu Ala Gly Glu Glu Phe Met Gly Leu Gly Leu 
1025                1030                1035                1040


Gly Asn Leu Val Ser Gly Gly Val Asp Lys Arg Gln Met Ala Ser Phe 
                1045                1050                1055


Gln Glu Ser Val Gly Glu Thr Ser Ser Gln Ser Val Val Val Ala Val 
            1060                1065                1070


Asp Arg Ile Phe Thr Gly Ser Thr Arg Leu Asp Gly Asn Ala Ile Val 
        1075                1080                1085


Asp Phe Val Arg Trp Leu Cys Ala Val Ser Met Asp Glu Leu Ala Ser 
    1090                1095                1100


Pro His His Pro Arg Met Phe Ser Leu Gln Lys Ile Val Glu Ile Ser 
1105                1110                1115                1120


Tyr Tyr Asn Met Asn Arg Ile Arg Leu Gln Trp Ser Arg Ile Trp His 
                1125                1130                1135


Val Ile Gly Asp His Phe Asn Lys Val Gly Cys Asn Pro Asn Glu Asp 
            1140                1145                1150


Val Ala Ile Phe Ala Val Asp Ser Leu Arg Gln Leu Ser Met Lys Phe 
        1155                1160                1165


Leu Glu Lys Gly Glu Leu Ala Asn Phe Arg Phe Gln Lys Asp Phe Leu 
    1170                1175                1180


Arg Pro Phe Glu His Ile Met Lys Lys Asn Arg Ser Pro Thr Ile Arg 
1185                1190                1195                1200


Asp Met Ala Ile Arg Cys Ile Ala Gln Met Val Asn Ser Gln Ala Ala 
                1205                1210                1215


Asn Ile Arg Ser Gly Trp Lys Asn Ile Phe Ala Val Phe His Gln Ala 
            1220                1225                1230


Ala Ser Asp His Asp Gly Asn Ile Val Glu Leu Ala Phe Gln Thr Thr 
        1235                1240                1245


Cys His Ile Val Thr Thr Ile Phe Gln His His Phe Pro Ala Ala Ile 
    1250                1255                1260


Asp Ser Phe Gln Asp Ala Val Lys Cys Leu Ser Glu Phe Ala Cys Asn 
1265                1270                1275                1280


Ala Ala Phe Pro Asp Thr Ser Met Glu Ala Ile Arg Leu Ile Arg Phe 
                1285                1290                1295


Cys Gly Lys Tyr Val Ser Glu Arg Pro Arg Val Leu Gln Glu Tyr Thr 
            1300                1305                1310


Ser Asp Asp Met Asn Val Ala Pro Gly Asp Arg Val Trp Val Arg Gly 
        1315                1320                1325


Trp Phe Pro Ile Leu Phe Glu Leu Ser Cys Ile Ile Asn Arg Cys Lys 
    1330                1335                1340


Leu Asp Val Arg Thr Arg Gly Leu Thr Val Met Phe Glu Ile Met Lys 
1345                1350                1355                1360


Ser Tyr Gly His Thr Phe Glu Lys His Trp Trp Gln Asp Leu Phe Arg 
                1365                1370                1375


Ile Val Phe Arg Ile Phe Asp Asn Met Lys Leu Pro Glu Gln Leu Ser 
            1380                1385                1390


Glu Lys Ser Glu Trp Met Thr Thr Thr Cys Asn His Ala Leu Tyr Ala 
        1395                1400                1405


Ile Cys Asp Val Phe Thr Gln Phe Tyr Glu Ala Leu Asn Glu Val Leu 
    1410                1415                1420


Leu Ser Asp Val Phe Ala Gln Leu Gln Trp Cys Val Lys Gln Asp Asn 
1425                1430                1435                1440


Glu Gln Leu Ala Arg Ser Gly Thr Asn Cys Leu Glu Asn Leu Val Ile 
                1445                1450                1455


Ser Asn Gly Glu Lys Phe Ser Pro Glu Val Trp Asp Glu Thr Cys Asn 
            1460                1465                1470


Cys Met Leu Asp Ile Phe Lys Thr Thr Ile Pro His Val Leu Leu Thr 
        1475                1480                1485


Trp Arg Pro Val Gly Met Glu Glu Asp Ser Ser Glu Lys His Leu Asp 
    1490                1495                1500


Val Asp Leu Asp Arg Gln Ser Leu Ser Ser Ile Asp Lys Asn Pro Ser 
1505                1510                1515                1520


Glu Arg Gly Gln Ser Gln Leu Ser Asn Pro Thr Asp Asp Ser Trp Lys 
                1525                1530                1535


Gly Arg Pro Tyr Ala Asn Gln Lys Leu Phe Ala Ser Leu Leu Ile Lys 
            1540                1545                1550


Cys Val Val Gln Leu Glu Leu Ile Gln Thr Ile Asp Asn Ile Val Phe 
        1555                1560                1565


Tyr Pro Ala Thr Ser Lys Lys Glu Asp Ala Glu His Met Val Ala Ala 
    1570                1575                1580


Gln Gln Asp Thr Leu Asp Ala Asp Ile His Ile Glu Thr Glu Asp Gln 
1585                1590                1595                1600


Gly Met Tyr Lys Tyr Met Ser Ser Gln His Leu Phe Lys Leu Leu Asp 
                1605                1610                1615


Cys Leu Gln Glu Ser His Ser Phe Ser Lys Ala Phe Asn Ser Asn Tyr 
            1620                1625                1630


Glu Gln Arg Thr Val Leu Trp Arg Ala Gly Phe Lys Gly Lys Ser Lys 
        1635                1640                1645


Pro Asn Leu Leu Lys Gln Glu Thr Ser Ser Leu Ala Cys Cys Leu Arg 
    1650                1655                1660


Ile Leu Phe Arg Met Tyr Val Asp Glu Asn Arg Arg Asp Ser Trp Glu 
1665                1670                1675                1680


Glu Ile Gln Gln Arg Leu Leu Thr Val Cys Ser Glu Ala Leu Ala Tyr 
                1685                1690                1695


Phe Ile Thr Val Asn Ser Glu Ser His Arg Glu Ala Trp Thr Ser Leu 
            1700                1705                1710


Leu Leu Leu Leu Leu Thr Lys Thr Leu Lys Ile Asn Asp Glu Lys Phe 
        1715                1720                1725


Lys Ala His Ala Ser Met Tyr Tyr Pro Tyr Leu Cys Glu Ile Met Gln 
    1730                1735                1740


Phe Asp Leu Ile Pro Glu Leu Arg Ala Val Leu Arg Lys Phe Phe Leu 
1745                1750                1755                1760


Arg Ile Gly Val Val Tyr Lys Ile Trp Ile Pro Glu Glu Pro Ser Gln 
                1765                1770                1775


Val Pro Ala Ala Leu Ser Pro Val Trp 
            1780                1785


<210>  10201
<211>  490
<212>  DNA
<213>  Homo sapiens

<400>  10201
gagttgatga aaactcacag accaacggga tagccgatga caggcagtcc ttgtcgtcag     60

cagataatct ggaatcggat gcacaaggac atcaagtggc tgccaggttc tcccacgttc    120

tgcagaagga tgccttcctt gtgttccgct ccctgtgcaa gctgtccatg aaaccccttg    180

gtgaaggccc tccagaccca aagtaagcag acagcagttc ttggccacct tcagtccaat    240

gatccagcag cacatggtac tgtgtttcac acttcccttg ttccaagaag tttcagtgtc    300

atgtctcttt gtcagtgtaa gtgcaggaac ggttttacaa cttttcagac tcatgcagtc    360

tctagagtcc tttcatatgg aattgtctct gtatccccac caaccaagat tttgcccagt    420

tttgcttttc ttggcatatg aatgctaaaa aagtctgttt attgaacaca taaaaaacac    480

atttttacta                                                           490


<210>  10202
<211>  44
<212>  PRT
<213>  Homo sapiens

<400>  10202

Met Thr Gly Ser Pro Cys Arg Gln Gln Ile Ile Trp Asn Arg Met His 
1               5                   10                  15


Lys Asp Ile Lys Trp Leu Pro Gly Ser Pro Thr Phe Cys Arg Arg Met 
            20                  25                  30


Pro Ser Leu Cys Ser Ala Pro Cys Ala Ser Cys Pro 
        35                  40


<210>  10203
<211>  622
<212>  DNA
<213>  Homo sapiens

<400>  10203
tatttgctgg aagagagtca gagctggaag tgttccttga ctgctagaaa gttcttacgg     60

ctgcctgtct gcaactaacc tccttagtgt gccccgtcat tctctccatt ttaagtctct    120

tgtgccccct cctcttcctt catccatgca ggacaggctg cttctggaat gggtgggtgg    180

gtgggcaggt cagggagttc cctagctttt ttaccagtcc agcctattct gggcagttag    240

ggccaggcta ttctgactcc accctttggc tgctggcttt tgctgagggt tcgtatttga    300

caatttctgg atataagtga gtgtgtatgt ttcagaccca agtaggcgat tttctgggag    360

atagcgcaag gttcaacaag gaggtgatgt atgcctacgt ggaccaactt gacttctgtg    420

aaaaagaatt tgtctcagcc ctgcggacat tcctagaagg tttccgccta cctggagaag    480

cccaaaagat tgaccgatta atggagaagt ttgccgcaag atacatagaa tgcaaccaag    540

ggcaaactct gtttgctagt gctgacactg cttatgtcct agcgtattca attattatgc    600

tgactacaga cttgcacagt cc                                             622


<210>  10204
<211>  97
<212>  PRT
<213>  Homo sapiens

<400>  10204

Met Phe Gln Thr Gln Val Gly Asp Phe Leu Gly Asp Ser Ala Arg Phe 
1               5                   10                  15


Asn Lys Glu Val Met Tyr Ala Tyr Val Asp Gln Leu Asp Phe Cys Glu 
            20                  25                  30


Lys Glu Phe Val Ser Ala Leu Arg Thr Phe Leu Glu Gly Phe Arg Leu 
        35                  40                  45


Pro Gly Glu Ala Gln Lys Ile Asp Arg Leu Met Glu Lys Phe Ala Ala 
    50                  55                  60


Arg Tyr Ile Glu Cys Asn Gln Gly Gln Thr Leu Phe Ala Ser Ala Asp 
65                  70                  75                  80


Thr Ala Tyr Val Leu Ala Tyr Ser Ile Ile Met Leu Thr Thr Asp Leu 
                85                  90                  95


His 



<210>  10205
<211>  2991
<212>  DNA
<213>  Homo sapiens

<400>  10205
aagagagagg aaaaaaaatt caaaataaac aaacaaacaa acaaggcaga accaacctct     60

acttcaaagc agccggcaca agccacccgt gtctgccacc cagagagggg ggtctctggc    120

ccgtggtgga ggagttgcag gggggatcgt cagggggaca gaggccgagt gacgtcctag    180

gagccaccgg gcaagaggcg gaggagaccc agagaggcca gagagacagc gggccccagc    240

gcgcggctcg gggctggggc gccagaagtg ggactggagc gaagtagagg atgccgagga    300

gaaaacagca ggcacccaag cgggcggcag gctacgccca ggaggaacag ctgaaagaag    360

aggaggaaat aaaagaagaa gtgattttga ttggcaccaa gacgctctgt ccaaaagcct    420

gcagcagaac ttgccttctc ggtccgtctc gaaacccagc ctgttcagct cggtgcagtt    480

gtaccgacag agcagcaaga tgtgcgggac tgtgttcaca ggggccagca gattccgatg    540

ccgacagtgc agcgcggcct atgacaccct agtcgagctg actgtgcaca tgaatgaaac    600

gggccactat caagatgaca accgcaaaaa ggacaagctc agacccacga gctattcaaa    660

gcccaggaaa agggctttcc aggatatgga caaagaggat gctcaaaagg ttctgaaatg    720

tatgttttgt ggcgactcct ttgattccct ccaagatttg agcgtccaca tgattaaaac    780

aaaacattac caaaaagtgc ctttgaagga gccagtccca accatttcct cgaaaatggt    840

caccccggct aagaaacgcg tttttgatgt caatcggccg tgttcccccg attcaaccac    900

aggatctttt gcagattctt tttcttctca gaagaacgcc aacttgcagt tgtcctccaa    960

caaccgctat ggctaccaaa atggagccag ctacacctgg cagtttgagg cctgcaagtc   1020

ccagatctta aagtgcatgg agtgtgggag ctcccatgac accttgcagc agctcaccac   1080

ccacatgatg gtcacaggtc actttctcaa ggtcaccagc tctgcctcca agaaagggaa   1140

gcagctggta ttagacccgt tagcagtgga gaaaatgcag tcgttgtctg aggccccaaa   1200

cagtgattct ctggctccca agccatccag taactcagca tcagattgta cagcctctac   1260

aactgagtta aagaaagaga gtaaaaaaga aaggccagag gaaaccagca aggatgagaa   1320

agtcgtgaaa agcgaggact atgaagatcc tctacaaaaa cctttagacc ctacaatcaa   1380

atatcaatac ctaagggagg aagacttgga agatggctca aagggtggag gggacatttt   1440

gaaatctttg gaaaatactg tcaccacagc catcaacaaa gcccaaaacg gggcccccag   1500

ctggagtgcc taccccagca tccacgcagc ctaccagctg tctgagggca ccaagccgcc   1560

tttgcctatg ggatcccagg tactgcagat ccggcctaat ctcaccaaca agctgaggcc   1620

cattgcacca aagtggaaag tgatgccact ggtttctatg cccacacacc tggcccctta   1680

cactcaagtc aagaaagagt cagaagacaa agatgaagcg gtgaaggagt gtgggaaaga   1740

aagtccccac gaagaggcct catctttcag ccacagtgag ggcgattctt tccgcaaaag   1800

tgaaacacct ccagaagcca aaaagaccga gctgggtccc ctgaaggagg aggagaagct   1860

gatgaaagag ggcagcgaga aggagaaacc ccagcccctg gagcccacat ctgctctgag   1920

caatgggtgc gccctcgcca accacgcccc ggccctgcca tgcatcaacc cactcagcgc   1980

cctgcagtcc gtcctgaaca atcacttggg caaagccacg gagcccttgc gctcaccttc   2040

ctgctccagc ccaagttcaa gcacaatttc catgttccac aagtcgaatc tcaatgtcat   2100

ggacaagccg gtcttgagtc ctgcctccac aaggtcagcc agcgtgtcca ggcgctacct   2160

gtttgagaac agcgatcagc ccattgacct gaccaagtcc aaaagcaaga aagccgagtc   2220

ctcgcaagca caatcttgta tgtccccacc tcagaagcac gctctgtctg acatcgccga   2280

catggtcaaa gtcctcccca aagccaccac cccaaagcca gcctcctcct ccagggtccc   2340

ccccatgaag ctggaaatgg atgtcaggcg ctttgaggat gtctccagtg aagtctcaac   2400

tttgcataaa agaaaaggcc ggcagtccaa ctggaatcct cagcatcttc tgattctaca   2460

agcccagttt gcctcgagcc tcttccagac atcagagggc aaatacctgc tgtctgatct   2520

gggcccacaa gagcgtatgc aaatctctaa gtttacggga ctctcaatga ccactatcag   2580

tcactggctg gccaacgtca agtaccagct taggaaaacg ggcgggacaa aatttctgaa   2640

aaacatggac aaaggccacc ccatctttta ttgcagtgac tgtgcctccc agttcagaac   2700

cccttctacc tacatcagtc acttagaatc tcacctgggt ttccaaatga aggacatgac   2760

ccgcttgtca gtggaccagc aaagcaaggt ggagcaagag atctcccggg tatcgtcggc   2820

tcagaggtct ccagaaacaa tagctgccga agaggacaca gactctaaat tcaagtgtaa   2880

gttgtgctgt cggacatttg tgagcaaaca tgcggtaaaa ctccacctaa gcaaaacgca   2940

cagcaagtca cccgaacacc attcacagtt tgtaacagac gtggatgaag a            2991


<210>  10206
<211>  93
<212>  PRT
<213>  Homo sapiens

<400>  10206

Met Pro Arg Arg Lys Gln Gln Ala Pro Lys Arg Ala Ala Gly Tyr Ala 
1               5                   10                  15


Gln Glu Glu Gln Leu Lys Glu Glu Glu Glu Ile Lys Glu Glu Val Ile 
            20                  25                  30


Leu Ile Gly Thr Lys Thr Leu Cys Pro Lys Ala Cys Ser Arg Thr Cys 
        35                  40                  45


Leu Leu Gly Pro Ser Arg Asn Pro Ala Cys Ser Ala Arg Cys Ser Cys 
    50                  55                  60


Thr Asp Arg Ala Ala Arg Cys Ala Gly Leu Cys Ser Gln Gly Pro Ala 
65                  70                  75                  80


Asp Ser Asp Ala Asp Ser Ala Ala Arg Pro Met Thr Pro 
                85                  90


<210>  10207
<211>  1622
<212>  DNA
<213>  Homo sapiens

<400>  10207
gagcttctgg aacagccgga aaccttgtca actgtccagg tagtttgtcc acctgaagtc     60

tcacctatga cttctctgga tcctttggca tcctagcact gaaatctgca aagctgctta    120

tgtactttct gtaaggtgaa aattacggat gcagcacctg tgattaagtc atgatggctg    180

gaagtaaatc ttggtgaata tttctaaatg ttttccacat ttcccataca gaggtttgat    240

aatttgttca cctagtttcc attttataat tgaggttggc agtggagacc aagactcgat    300

gtggtgtggg tcaatttgga agaattactt cgaagaaaat gagaaagaaa cactcaaatg    360

aaatcccttt tgaggaagga gatactcttt tccttaaaaa aaaaaaaatc aacatttgta    420

tcaataaagg ttgagatcag aaaatgtttc ccgttcaatg agaaagattt ggactgtgat    480

gaagataaac taaaaagaaa agagtttgac caactggcaa gggtttgacc cctttcccct    540

ttaaaaaaat cacactaaaa ctacagctta tgtttcgcat gagtggatgc tctgaattgc    600

aatgcaaagt gcttatgaaa acttaagatc ttacattact acttcaaaga gtacatgtga    660

taggaattcc tatagaagaa aatgaaaaag gatatagctt gaaaatccaa atttatagca    720

aattctgcat ctatcatttg gcgatgctat gactggatgc tatcactatt tggaagtatc    780

aaaaatatta caaaggaaaa ttaagcttca ttttactcta tcttcttata aagtgaggcc    840

cacatcctgg tgatgactat ttccttaatg agactatggg attttatcaa actccataaa    900

acatgattgc atttccttca ctctgaaatc accttatttt aatttccaca tgaaattggg    960

atgcaatttg tgtgtacatt taatatgcga gggttccttc tccacctctc actcactcct   1020

ccccaaaaaa gctttggcca aatctacagc atgttttaca atggacagag tcttaggatt   1080

gaggcaagta caatcaagag gagtcagggg ctaagataaa caaaagaaca tgaaaacagt   1140

gatggtgatg cctcatgtga ttagctctat ggtcccttcc tcttctcaga gtgacaggca   1200

gaaaaatcga cagttaattc cagatccatc aggggctgtg ctgcctttct acagaaatga   1260

tgagtttaga gagcaagctg cagatgagtg tctgagcact cgcgggaggt gccgagtgtc   1320

atggcagaag ttcgtgtggc atcgctgtct gctgcgtcca agagatgata gggtccttcc   1380

agaagaggaa cagcagggta gcgcagaaat ggaaggaaga ccactcttcc cagtttctgg   1440

ccaatgggat gagggaagaa gtgatgggca tcagttacag aactcattca caccttcaat   1500

ggttttggaa gccacatgct ccagatggca gagctaccct ggaaagaagg ttgcatctga   1560

gtcaccacgt ggagatcaac tttgtacatg tgaaacataa atgtttactg tgttgggcca   1620

ct                                                                  1622


<210>  10208
<211>  156
<212>  PRT
<213>  Homo sapiens

<400>  10208

Met Lys Thr Val Met Val Met Pro His Val Ile Ser Ser Met Val Pro 
1               5                   10                  15


Ser Ser Ser Gln Ser Asp Arg Gln Lys Asn Arg Gln Leu Ile Pro Asp 
            20                  25                  30


Pro Ser Gly Ala Val Leu Pro Phe Tyr Arg Asn Asp Glu Phe Arg Glu 
        35                  40                  45


Gln Ala Ala Asp Glu Cys Leu Ser Thr Arg Gly Arg Cys Arg Val Ser 
    50                  55                  60


Trp Gln Lys Phe Val Trp His Arg Cys Leu Leu Arg Pro Arg Asp Asp 
65                  70                  75                  80


Arg Val Leu Pro Glu Glu Glu Gln Gln Gly Ser Ala Glu Met Glu Gly 
                85                  90                  95


Arg Pro Leu Phe Pro Val Ser Gly Gln Trp Asp Glu Gly Arg Ser Asp 
            100                 105                 110


Gly His Gln Leu Gln Asn Ser Phe Thr Pro Ser Met Val Leu Glu Ala 
        115                 120                 125


Thr Cys Ser Arg Trp Gln Ser Tyr Pro Gly Lys Lys Val Ala Ser Glu 
    130                 135                 140


Ser Pro Arg Gly Asp Gln Leu Cys Thr Cys Glu Thr 
145                 150                 155


<210>  10209
<211>  486
<212>  DNA
<213>  Homo sapiens

<400>  10209
gctcattttc tcgactgtaa aatgaggaga acagcaattc caacctacag gattgttggc     60

gaccttaaat gagaaagtcc aagtgcactg ctttgacaca cagaccgcct cacacctgag    120

ggtatacagt gttcaaaaaa gcaaggggat gaaagaccca gatgcaaagc cttgaagaga    180

aaatgaaggc aagttcttgt acttcacaca caaaaatccc gtaatgacct gaatgatggc    240

tgattcttaa ctgggctcca gagacactgg atgggcttcc caggatgcca gaaccctgaa    300

attacagagt ccttcctata attccgggtt ccttcaagta agaggtcggg cagcagattc    360

ttgatgcctc cgggatgttg tctcttggcc tgaacaagat ttgcagaaat gtacaattat    420

tctagggaca gacaatattg agaagggaga attcctcttg ctcattgaga gggaaaggga    480

ctctca                                                               486


<210>  10210
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  10210

Leu Gly Ser Arg Asp Thr Gly Trp Ala Ser Gln Asp Ala Arg Thr Leu 
1               5                   10                  15


Lys Leu Gln Ser Pro Ser Tyr Asn Ser Gly Phe Leu Gln Val Arg Gly 
            20                  25                  30


Arg Ala Ala Asp Ser 
        35


<210>  10211
<211>  828
<212>  DNA
<213>  Homo sapiens

<400>  10211
atggggctgt tgcaaggatt tgatgaagtt caccccacaa agccctttcc acaacgtctg     60

cctacaatcc aagaaaagca cgctgctgcc ccgcaagacc agaacacaga gcccctccct    120

ccccaggagc cggacctgag cagcaggggg ttaaagagca gtacccgggc tgtccccggg    180

tcagggtcgt ttgcacgaag gcagagccgc ggaagaggga aggaaatgcc ccgggtccca    240

ggcggggcct cgagcgtgcc cacgccgccc cctgctggcc acgcctggag ttgcaggaac    300

cgggcgccgg gcgggacctc agctgcgggc tccgcgctgc tcccgcgccg cgtgggtgaa    360

gcgccctccc cggccacgca ctggggtctc acaggggcca ggctgaaaaa caatgcacgc    420

cttaaaggcg ggaggctggc ctggcgcagg ctgaggaaca ctgatgaacg acctcctgca    480

aaggattgtc cccagaggac agggctaggg ggaagcagga cggcgcagcg tctacacccc    540

cgcgcgtggg tggcccccgg aactgcccac acccctggct cccgggtcag ccggtcactg    600

ccagatgcac cacccccacc gccacagcca ggagagggga tgacatgggg ggctctggat    660

ctcttaactc ctcaggcctc cccaccaggc aaggttcacc acccctcctt ccagcagcct    720

ctagaaggtg gaacgggcaa ggaaacggat tctacgctag agcctcccga ggagaacaca    780

gctggccggc acctggattt tagcccagga gactgtgacg gatgctga                 828


<210>  10212
<211>  275
<212>  PRT
<213>  Homo sapiens

<400>  10212

Met Gly Leu Leu Gln Gly Phe Asp Glu Val His Pro Thr Lys Pro Phe 
1               5                   10                  15


Pro Gln Arg Leu Pro Thr Ile Gln Glu Lys His Ala Ala Ala Pro Gln 
            20                  25                  30


Asp Gln Asn Thr Glu Pro Leu Pro Pro Gln Glu Pro Asp Leu Ser Ser 
        35                  40                  45


Arg Gly Leu Lys Ser Ser Thr Arg Ala Val Pro Gly Ser Gly Ser Phe 
    50                  55                  60


Ala Arg Arg Gln Ser Arg Gly Arg Gly Lys Glu Met Pro Arg Val Pro 
65                  70                  75                  80


Gly Gly Ala Ser Ser Val Pro Thr Pro Pro Pro Ala Gly His Ala Trp 
                85                  90                  95


Ser Cys Arg Asn Arg Ala Pro Gly Gly Thr Ser Ala Ala Gly Ser Ala 
            100                 105                 110


Leu Leu Pro Arg Arg Val Gly Glu Ala Pro Ser Pro Ala Thr His Trp 
        115                 120                 125


Gly Leu Thr Gly Ala Arg Leu Lys Asn Asn Ala Arg Leu Lys Gly Gly 
    130                 135                 140


Arg Leu Ala Trp Arg Arg Leu Arg Asn Thr Asp Glu Arg Pro Pro Ala 
145                 150                 155                 160


Lys Asp Cys Pro Gln Arg Thr Gly Leu Gly Gly Ser Arg Thr Ala Gln 
                165                 170                 175


Arg Leu His Pro Arg Ala Trp Val Ala Pro Gly Thr Ala His Thr Pro 
            180                 185                 190


Gly Ser Arg Val Ser Arg Ser Leu Pro Asp Ala Pro Pro Pro Pro Pro 
        195                 200                 205


Gln Pro Gly Glu Gly Met Thr Trp Gly Ala Leu Asp Leu Leu Thr Pro 
    210                 215                 220


Gln Ala Ser Pro Pro Gly Lys Val His His Pro Ser Phe Gln Gln Pro 
225                 230                 235                 240


Leu Glu Gly Gly Thr Gly Lys Glu Thr Asp Ser Thr Leu Glu Pro Pro 
                245                 250                 255


Glu Glu Asn Thr Ala Gly Arg His Leu Asp Phe Ser Pro Gly Asp Cys 
            260                 265                 270


Asp Gly Cys 
        275


<210>  10213
<211>  562
<212>  DNA
<213>  Homo sapiens

<400>  10213
tcttcacacc tctcttacta caccctttgc catggtgtgc cctcctgagt cacaacagct     60

tggccatggg acttggtttg gccattggga tgttcatgga gccaacagag gcttgcatgg    120

ggcccgtgtg ttaagctttc atctctggag ccccttctcc tgctatgaga aggacatacc    180

tggctggcct gctggaggaa aagagacttg gggagtagag atcaaggtat ttggcagctg    240

ctggaaagtt ttccacatcc agtgattggc tgcatttggt ggacacaggg actcatcact    300

atatgaactt taaagggata cagcttgtga aaaattcctc tgataaaagt caaggctact    360

tcaagagatg gttttgaacg agcacttatg tcttgcctgc tagaactgtg aaatttcaga    420

ctttctagaa aaaaactaag catttatttc agtagctctt ctcattccct gaccaatgaa    480

ccaacatagc cattctgctg ctggttctgg agacaattac catgagcagc atccatgttc    540

tttacagcct actccactct ca                                             562


<210>  10214
<211>  77
<212>  PRT
<213>  Homo sapiens

<400>  10214

Met Val Cys Pro Pro Glu Ser Gln Gln Leu Gly His Gly Thr Trp Phe 
1               5                   10                  15


Gly His Trp Asp Val His Gly Ala Asn Arg Gly Leu His Gly Ala Arg 
            20                  25                  30


Val Leu Ser Phe His Leu Trp Ser Pro Phe Ser Cys Tyr Glu Lys Asp 
        35                  40                  45


Ile Pro Gly Trp Pro Ala Gly Gly Lys Glu Thr Trp Gly Val Glu Ile 
    50                  55                  60


Lys Val Phe Gly Ser Cys Trp Lys Val Phe His Ile Gln 
65                  70                  75


<210>  10215
<211>  2590
<212>  DNA
<213>  Homo sapiens

<400>  10215
cgctgtcctg ggtgcgcctc gggccgctgc gctcctggcc agctcccccc agcgcctggg     60

aggcgacccc cagtgcgccc gggttcaaag gcccggcgag gcagttccag cccctctggg    120

gggcggggag gcgacggggg tggtgcagaa gccagaaaag cccgagccac agccggccag    180

ctccgcgcag ggatgggcag cgcgctctga aagtttatga ccgccgcagc caactcctgg    240

ccggagctgg agacgcagcg agcgatcggc cggcctcgaa cccccacagc tggagggcga    300

ggccagctgt acccggcccc agtgcccttt cgcggccaca agcggccgtc ctcctggtcc    360

ggtgctccgg cgcctgatct aggttcatgg agccggggct gtggctcctt ttcgggctca    420

cagtgacctc cgccgcagga ttcgtgcctt gctcccagtc tggggatgct ggcaggcgcg    480

gcgtgtccca ggcccccact gcagccagat ctgaggggga ctgtgaagag actgtggctg    540

gccctggcga ggagactgtg gctggccctg gcgaggggac tgtggccccg acagcactgc    600

agggtccaag ccctggaagc cctgggcagg agcaggcggc cgagggggcc cctgagcacc    660

accgatccag gcgctgcacg tgcttcacct acaaggacaa ggagtgtgtc tactattgcc    720

acctggacat catttggatc aacactcccg aacagacggt gccctatgga ctgtccaact    780

acagaggaag cttccggggc aagaggtctg cggggccact tccagggaat ctgcagctct    840

cacatcggcc acacttgcgc tgcgcttgtg tggggagata tgacaaggcc tgcctgcact    900

tttgcaccca aactctggac gtcagcaggt tgaagtcaag gaccaacaaa gcaagcaggc    960

tttagacctc caccatccaa agctcatgcc cggcagtgga ctcgccctcg ctccatctac   1020

ctgcccccgc tgcctctttc aggaaggagc cccttaggag gacaggcctg cagcatcctg   1080

gtctcgggag gcttctgtca ttgctcacac acagttcaga tttccacctc tttatagaca   1140

agaagtgaat ttgcctgggg cagaacaccc acccaaagag tccccactta acaatacccc   1200

ccccccacgg caagaatgcc caaatccgaa tgaccccagt tttcctaatg agtaaaatga   1260

tcccagatgt gccccagagc atgacgcctg cagctccggt ttcatgcagg aaattggttt   1320

tggagagttt tggcaagttg gaaagccact tactggcttt tgacatgact tctcttggag   1380

aataagtgga ctccaagcta actctttgca aatgtaaaca catgtccatc ttgtaataaa   1440

tgcaaaatgc ccgtgcagca gaagcatgcg actttcatat ccttgcctag aataggctgc   1500

atggtgtatg tcagtgaggg ccacgaggcg tcggctttag acacagatca tagctctaca   1560

ggagtttatg aatttgaagc ttatgggatt ttggcagaga aattttcagc tgtgcttgat   1620

acccaccaaa agaatgtatc tcgaaagaat gaaggaagaa gaaaaaagga tccttgatgt   1680

ttgtgacaag aaaatgagaa agttagtatc tgcaatacag agcttgttcc tgttcagtga   1740

ctgaccctct gtattctgta tagacaccag gccgatacac agtggagttc ccaggccttg   1800

tttgcaggaa gccgactgta aagacagccc cagctcaagg ctattaggtt gaatatttgc   1860

tttcatgagt aaatgtggat ctttggggaa tggcttcaaa ataagtcacg aacacaaatt   1920

ctttgtaaat tatgtaaatt cctgtttata taaattggca acaacttata ccgtctgaca   1980

gttcaaaatc tctttcagct gcgctcttcc caccgagccg agcttactgt gagtgtggag   2040

atgttatccc accatgtaaa gtcgcctgcg caggggaggg ctgcccatct ccccaaccca   2100

gtcacagaga gataggaaac ggcatttgag tgggtgtcca gggccccgta gagagacatt   2160

taagatggtg tatgacagag cattggcctt gaccaaatgt taaatcctct gtgtgtattt   2220

cataagttat tacaggtata aaagtgatga cctatcatga ggaaatgaaa gtggctgatt   2280

tgctggtagg attttgtaca gtttagagaa gcgattattt attgtgaaac tgttctccac   2340

tccaactcct ttatgtggat ctgttcaaag tagtcactgt atatacgtat agagaggtag   2400

ataggtaggt agattttaaa ttgcattctg aatacaaact catactcctt agagcttgaa   2460

ttacattttt aaaatgcata tgtgctgttt ggcaccgtgg caagatggta tcagagagaa   2520

acccatcaat tgctcaaata ctcagaaagt actgtcaaaa gcctaataaa aaacctaaag   2580

tttgctctga                                                          2590


<210>  10216
<211>  192
<212>  PRT
<213>  Homo sapiens

<400>  10216

Met Glu Pro Gly Leu Trp Leu Leu Phe Gly Leu Thr Val Thr Ser Ala 
1               5                   10                  15


Ala Gly Phe Val Pro Cys Ser Gln Ser Gly Asp Ala Gly Arg Arg Gly 
            20                  25                  30


Val Ser Gln Ala Pro Thr Ala Ala Arg Ser Glu Gly Asp Cys Glu Glu 
        35                  40                  45


Thr Val Ala Gly Pro Gly Glu Glu Thr Val Ala Gly Pro Gly Glu Gly 
    50                  55                  60


Thr Val Ala Pro Thr Ala Leu Gln Gly Pro Ser Pro Gly Ser Pro Gly 
65                  70                  75                  80


Gln Glu Gln Ala Ala Glu Gly Ala Pro Glu His His Arg Ser Arg Arg 
                85                  90                  95


Cys Thr Cys Phe Thr Tyr Lys Asp Lys Glu Cys Val Tyr Tyr Cys His 
            100                 105                 110


Leu Asp Ile Ile Trp Ile Asn Thr Pro Glu Gln Thr Val Pro Tyr Gly 
        115                 120                 125


Leu Ser Asn Tyr Arg Gly Ser Phe Arg Gly Lys Arg Ser Ala Gly Pro 
    130                 135                 140


Leu Pro Gly Asn Leu Gln Leu Ser His Arg Pro His Leu Arg Cys Ala 
145                 150                 155                 160


Cys Val Gly Arg Tyr Asp Lys Ala Cys Leu His Phe Cys Thr Gln Thr 
                165                 170                 175


Leu Asp Val Ser Arg Leu Lys Ser Arg Thr Asn Lys Ala Ser Arg Leu 
            180                 185                 190


<210>  10217
<211>  2636
<212>  DNA
<213>  Homo sapiens

<400>  10217
cgctgtcctg ggtgcgcctc gggccgctgc gctcctggcc agctcccccc agcgcctggg     60

aggcgacccc cagtgcgccc gggttcaaag gcccggcgag gcagttccag cccctctggg    120

gggcggggag gcgacggggg tggtgcagaa gccagaaaag cccgagccac agccggccag    180

ctccgcgcag ggatgggcag cgcgctctga aagtttatga ccgccgcagc caactcctgg    240

ccggagctgg agacgcagcg agcgatcggc cggcctcgaa cccccacagc tggagggcga    300

ggccagctgt acccggcccc agtgcccttt cgcggccaca agcggccgtc ctcctggtcc    360

ggtgctccgg cgcctgatct aggttcatgg agccggggct gtggctcctt ttcgggctca    420

cagtgacctc cgccgcagga ttcgtgcctt gctcccagtc tggggatgct ggcaggcgcg    480

gcgtgtccca ggcccccact gcagccagat ctgaggggga ctgtgaagag actgtggctg    540

gccctggcga ggagactgtg gctggccctg gcgaggggac tgtggccccg acagcactgc    600

agggtccaag ccctggaagc cctgggcagg agcaggcggc cgagggggcc cctgagcacc    660

accgatccag gcgctgcacg tgcttcacct acaaggacaa ggagtgtgtc tactattgcc    720

acctggacat catttggatc aacactcccg aacagacggt gccctatgga ctgtccaact    780

acagaggaag cttccggggc aagaggtctg cggggccact tccagggaat ctgcagctct    840

cacatcggcc acacttgcgc tgcgcttgtg tggggagata tgacaaggcc tgcctgcact    900

tttgcaccca aactctggac gtcagcagta attcaaggac ggcagaaaaa acagacaaag    960

aagaggaagg gaaggttgaa gtcaaggacc aacaaagcaa gcaggcttta gacctccacc   1020

atccaaagct catgcccggc agtggactcg ccctcgctcc atctacctgc ccccgctgcc   1080

tctttcagga aggagcccct taggaggaca ggcctgcagc atcctggtct cgggaggctt   1140

ctgtcattgc tcacacacag ttcagatttc cacctcttta tagacaagaa gtgaatttgc   1200

ctggggcaga acacccaccc aaagagtccc cacttaacaa tacccccccc ccacggcaag   1260

aatgcccaaa tccgaatgac cccagttttc ctaatgagta aaatgatccc agatgtgccc   1320

cagagcatga cgcctgcagc tccggtttca tgcaggaaat tggttttgga gagttttggc   1380

aagttggaaa gccacttact ggcttttgac atgacttctc ttggagaata agtggactcc   1440

aagctaactc tttgcaaatg taaacacatg tccatcttgt aataaatgca aaatgcccgt   1500

gcagcagaag catgcgactt tcatatcctt gcctagaata ggctgcatgg tgtatgtcag   1560

tgagggccac gaggcgtcgg ctttagacac agatcatagc tctacaggag tttatgaatt   1620

tgaagcttat gggattttgg cagagaaatt ttcagctgtg cttgataccc accaaaagaa   1680

tgtatctcga aagaatgaag gaagaagaaa aaaggatcct tgatgtttgt gacaagaaaa   1740

tgagaaagtt agtatctgca atacagagct tgttcctgtt cagtgactga ccctctgtat   1800

tctgtataga caccaggccg atacacagtg gagttcccag gccttgtttg caggaagccg   1860

actgtaaaga cagccccagc tcaaggctat taggttgaat atttgctttc atgagtaaat   1920

gtggatcttt ggggaatggc ttcaaaataa gtcacgaaca caaattcttt gtaaattatg   1980

taaattcctg tttatataaa ttggcaacaa cttataccgt ctgacagttc aaaatctctt   2040

tcagctgcgc tcttcccacc gagccgagct tactgtgagt gtggagatgt tatcccacca   2100

tgtaaagtcg cctgcgcagg ggagggctgc ccatctcccc aacccagtca cagagagata   2160

ggaaacggca tttgagtggg tgtccagggc cccgtagaga gacatttaag atggtgtatg   2220

acagagcatt ggccttgacc aaatgttaaa tcctctgtgt gtatttcata agttattaca   2280

ggtataaaag tgatgaccta tcatgaggaa atgaaagtgg ctgatttgct ggtaggattt   2340

tgtacagttt agagaagcga ttatttattg tgaaactgtt ctccactcca actcctttat   2400

gtggatctgt tcaaagtagt cactgtatat acgtatagag aggtagatag gtaggtagat   2460

tttaaattgc attctgaata caaactcata ctccttagag cttgaattac atttttaaaa   2520

tgcatatgtg ctgtttggca ccgtggcaag atggtatcag agagaaaccc atcaattgct   2580

caaatactca gaaagtactg tcaaaagcct aataaaaaac ctaaagtttg ctctga       2636


<210>  10218
<211>  238
<212>  PRT
<213>  Homo sapiens

<400>  10218

Met Glu Pro Gly Leu Trp Leu Leu Phe Gly Leu Thr Val Thr Ser Ala 
1               5                   10                  15


Ala Gly Phe Val Pro Cys Ser Gln Ser Gly Asp Ala Gly Arg Arg Gly 
            20                  25                  30


Val Ser Gln Ala Pro Thr Ala Ala Arg Ser Glu Gly Asp Cys Glu Glu 
        35                  40                  45


Thr Val Ala Gly Pro Gly Glu Glu Thr Val Ala Gly Pro Gly Glu Gly 
    50                  55                  60


Thr Val Ala Pro Thr Ala Leu Gln Gly Pro Ser Pro Gly Ser Pro Gly 
65                  70                  75                  80


Gln Glu Gln Ala Ala Glu Gly Ala Pro Glu His His Arg Ser Arg Arg 
                85                  90                  95


Cys Thr Cys Phe Thr Tyr Lys Asp Lys Glu Cys Val Tyr Tyr Cys His 
            100                 105                 110


Leu Asp Ile Ile Trp Ile Asn Thr Pro Glu Gln Thr Val Pro Tyr Gly 
        115                 120                 125


Leu Ser Asn Tyr Arg Gly Ser Phe Arg Gly Lys Arg Ser Ala Gly Pro 
    130                 135                 140


Leu Pro Gly Asn Leu Gln Leu Ser His Arg Pro His Leu Arg Cys Ala 
145                 150                 155                 160


Cys Val Gly Arg Tyr Asp Lys Ala Cys Leu His Phe Cys Thr Gln Thr 
                165                 170                 175


Leu Asp Val Ser Ser Asn Ser Arg Thr Ala Glu Lys Thr Asp Lys Glu 
            180                 185                 190


Glu Glu Gly Lys Val Glu Val Lys Asp Gln Gln Ser Lys Gln Ala Leu 
        195                 200                 205


Asp Leu His His Pro Lys Leu Met Pro Gly Ser Gly Leu Ala Leu Ala 
    210                 215                 220


Pro Ser Thr Cys Pro Arg Cys Leu Phe Gln Glu Gly Ala Pro 
225                 230                 235


<210>  10219
<211>  2671
<212>  DNA
<213>  Homo sapiens

<400>  10219
cgctgtcctg ggtgcgcctc gggccgctgc gctcctggcc agctcccccc agcgcctggg     60

aggcgacccc cagtgcgccc gggttcaaag gcccggcgag gcagttccag cccctctggg    120

gggcggggag gcgacggggg tggtgcagaa gccagaaaag cccgagccac agccggccag    180

ctccgcgcag ggatgggcag cgcgctctga aagtttatga ccgccgcagc caactcctgg    240

ccggagctgg agacgcagcg agcgatcggc cggcctcgaa cccccacagc tggagggcga    300

ggccagctgt acccggcccc agtgcccttt cgcggccaca agcggccgtc ctcctggtcc    360

ggtgctccgg cgcctgatct aggttcatgg agccggggct gtggctcctt ttcgggctca    420

cagtgacctc cgccgcagga ttcgtgcctt gctcccagtc tggggatgct ggcaggcgcg    480

gcgtgtccca ggcccccact gcagccagat ctgaggggga ctgtgaagag actgtggctg    540

gccctggcga ggagactgtg gctggccctg gcgaggggac tgtggccccg acagcactgc    600

agggtccaag ccctggaagc cctgggcagg agcaggcggc cgagggggcc cctgagcacc    660

accgatccag gcgctgcacg tgcttcacct acaaggacaa ggagtgtgtc tactattgcc    720

acctggacat catttggatc aacactcccg aacagacggt gccctatgga ctgtccaact    780

acagaggaag cttccggggc aagaggtctg cggggccact tccagggaat ctgcagctct    840

cacatcggcc acacttgcgc tgcgcttgtg tggggagata tgacaaggcc tgcctgcact    900

tttgcaccca aactctggac gtcagcagta attcaaggac ggcagaaaaa acagacaaag    960

aagaggaagg gaaggtgaga ggtgccaaca gaggcctgtg tcaaaggagg ttgaagtcaa   1020

ggaccaacaa agcaagcagg ctttagacct ccaccatcca aagctcatgc ccggcagtgg   1080

actcgccctc gctccatcta cctgcccccg ctgcctcttt caggaaggag ccccttagga   1140

ggacaggcct gcagcatcct ggtctcggga ggcttctgtc attgctcaca cacagttcag   1200

atttccacct ctttatagac aagaagtgaa tttgcctggg gcagaacacc cacccaaaga   1260

gtccccactt aacaataccc cccccccacg gcaagaatgc ccaaatccga atgaccccag   1320

ttttcctaat gagtaaaatg atcccagatg tgccccagag catgacgcct gcagctccgg   1380

tttcatgcag gaaattggtt ttggagagtt ttggcaagtt ggaaagccac ttactggctt   1440

ttgacatgac ttctcttgga gaataagtgg actccaagct aactctttgc aaatgtaaac   1500

acatgtccat cttgtaataa atgcaaaatg cccgtgcagc agaagcatgc gactttcata   1560

tccttgccta gaataggctg catggtgtat gtcagtgagg gccacgaggc gtcggcttta   1620

gacacagatc atagctctac aggagtttat gaatttgaag cttatgggat tttggcagag   1680

aaattttcag ctgtgcttga tacccaccaa aagaatgtat ctcgaaagaa tgaaggaaga   1740

agaaaaaagg atccttgatg tttgtgacaa gaaaatgaga aagttagtat ctgcaataca   1800

gagcttgttc ctgttcagtg actgaccctc tgtattctgt atagacacca ggccgataca   1860

cagtggagtt cccaggcctt gtttgcagga agccgactgt aaagacagcc ccagctcaag   1920

gctattaggt tgaatatttg ctttcatgag taaatgtgga tctttgggga atggcttcaa   1980

aataagtcac gaacacaaat tctttgtaaa ttatgtaaat tcctgtttat ataaattggc   2040

aacaacttat accgtctgac agttcaaaat ctctttcagc tgcgctcttc ccaccgagcc   2100

gagcttactg tgagtgtgga gatgttatcc caccatgtaa agtcgcctgc gcaggggagg   2160

gctgcccatc tccccaaccc agtcacagag agataggaaa cggcatttga gtgggtgtcc   2220

agggccccgt agagagacat ttaagatggt gtatgacaga gcattggcct tgaccaaatg   2280

ttaaatcctc tgtgtgtatt tcataagtta ttacaggtat aaaagtgatg acctatcatg   2340

aggaaatgaa agtggctgat ttgctggtag gattttgtac agtttagaga agcgattatt   2400

tattgtgaaa ctgttctcca ctccaactcc tttatgtgga tctgttcaaa gtagtcactg   2460

tatatacgta tagagaggta gataggtagg tagattttaa attgcattct gaatacaaac   2520

tcatactcct tagagcttga attacatttt taaaatgcat atgtgctgtt tggcaccgtg   2580

gcaagatggt atcagagaga aacccatcaa ttgctcaaat actcagaaag tactgtcaaa   2640

agcctaataa aaaacctaaa gtttgctctg a                                  2671


<210>  10220
<211>  219
<212>  PRT
<213>  Homo sapiens

<400>  10220

Met Glu Pro Gly Leu Trp Leu Leu Phe Gly Leu Thr Val Thr Ser Ala 
1               5                   10                  15


Ala Gly Phe Val Pro Cys Ser Gln Ser Gly Asp Ala Gly Arg Arg Gly 
            20                  25                  30


Val Ser Gln Ala Pro Thr Ala Ala Arg Ser Glu Gly Asp Cys Glu Glu 
        35                  40                  45


Thr Val Ala Gly Pro Gly Glu Glu Thr Val Ala Gly Pro Gly Glu Gly 
    50                  55                  60


Thr Val Ala Pro Thr Ala Leu Gln Gly Pro Ser Pro Gly Ser Pro Gly 
65                  70                  75                  80


Gln Glu Gln Ala Ala Glu Gly Ala Pro Glu His His Arg Ser Arg Arg 
                85                  90                  95


Cys Thr Cys Phe Thr Tyr Lys Asp Lys Glu Cys Val Tyr Tyr Cys His 
            100                 105                 110


Leu Asp Ile Ile Trp Ile Asn Thr Pro Glu Gln Thr Val Pro Tyr Gly 
        115                 120                 125


Leu Ser Asn Tyr Arg Gly Ser Phe Arg Gly Lys Arg Ser Ala Gly Pro 
    130                 135                 140


Leu Pro Gly Asn Leu Gln Leu Ser His Arg Pro His Leu Arg Cys Ala 
145                 150                 155                 160


Cys Val Gly Arg Tyr Asp Lys Ala Cys Leu His Phe Cys Thr Gln Thr 
                165                 170                 175


Leu Asp Val Ser Ser Asn Ser Arg Thr Ala Glu Lys Thr Asp Lys Glu 
            180                 185                 190


Glu Glu Gly Lys Val Arg Gly Ala Asn Arg Gly Leu Cys Gln Arg Arg 
        195                 200                 205


Leu Lys Ser Arg Thr Asn Lys Ala Ser Arg Leu 
    210                 215


<210>  10221
<211>  2415
<212>  DNA
<213>  Homo sapiens

<400>  10221
cgctgtcctg ggtgcgcctc gggccgctgc gctcctggcc agctcccccc agcgcctggg     60

aggcgacccc cagtgcgccc gggttcaaag gcccggcgag gcagttccag cccctctggg    120

gggcggggag gcgacggggg tggtgcagaa gccagaaaag cccgagccac agccggccag    180

ctccgcgcag ggatgggcag cgcgctctga aagtttatga ccgccgcagc caactcctgg    240

ccggagctgg agacgcagcg agcgatcggc cggcctcgaa cccccacagc tggagggcga    300

ggccagctgt acccggcccc agtgcccttt cgcggccaca agcggccgtc ctcctggtcc    360

ggtgctccgg cgcctgatct aggttcatgg agccggggct gtggctcctt ttcgggctca    420

cagtgacctc cgccgcagga ttcgtgcctt gctcccagtc tggggatgct ggcaggcgcg    480

gcgtgtccca ggcccccact gcagccagat ctgaggggga ctgtgaagag actgtggctg    540

gccctggcga ggagactgtg gctggccctg gcgaggggac tgtggccccg acagcactgc    600

agggtccaag ccctggaagc cctgggcagg agcaggcggc cgagggggcc cctgagcacc    660

accgatccag gcgctgcacg tgcttcacct acaaggacaa ggagtgtgtc tactattgcc    720

acctggacat catttggatc aacactcccg aacagacggt gccctatgga ctgtccaact    780

acagaggaag cttccggggc aagaggtctg cggggccact tccagggaat ctgcagctct    840

cacatcggcc acacttgcgc tgcgcttgtg tggggagata tgacaaggcc tgcctgcact    900

tttgcaccca aactctggac gtcagcagta attcaaggac ggcagaaaaa acagacaaag    960

aagaggaagg gaaggttgaa gtcaaggacc aacaaagcaa gcaggcttta gacctccacc   1020

atccaaagct catgcccggc agtggactcg ccctcgctcc atctacctgc ccccgctgcc   1080

tctttcagga aggagcccct taggaggaca ggcctgcact ccggtttcat gcaggaaatt   1140

ggttttggag agttttggca agttggaaag ccacttactg gcttttgaca tgacttctct   1200

tggagaataa gtggactcca agctaactct ttgcaaatgt aaacacatgt ccatcttgta   1260

ataaatgcaa aatgcccgtg cagcagaagc atgcgacttt catatccttg cctagaatag   1320

gctgcatggt gtatgtcagt gagggccacg aggcgtcggc tttagacaca gatcatagct   1380

ctacaggagt ttatgaattt gaagcttatg ggattttggc agagaaattt tcagctgtgc   1440

ttgataccca ccaaaagaat gtatctcgaa agaatgaagg aagaagaaaa aaggatcctt   1500

gatgtttgtg acaagaaaat gagaaagtta gtatctgcaa tacagagctt gttcctgttc   1560

agtgactgac cctctgtatt ctgtatagac accaggccga tacacagtgg agttcccagg   1620

ccttgtttgc aggaagccga ctgtaaagac agccccagct caaggctatt aggttgaata   1680

tttgctttca tgagtaaatg tggatctttg gggaatggct tcaaaataag tcacgaacac   1740

aaattctttg taaattatgt aaattcctgt ttatataaat tggcaacaac ttataccgtc   1800

tgacagttca aaatctcttt cagctgcgct cttcccaccg agccgagctt actgtgagtg   1860

tggagatgtt atcccaccat gtaaagtcgc ctgcgcaggg gagggctgcc catctcccca   1920

acccagtcac agagagatag gaaacggcat ttgagtgggt gtccagggcc ccgtagagag   1980

acatttaaga tggtgtatga cagagcattg gccttgacca aatgttaaat cctctgtgtg   2040

tatttcataa gttattacag gtataaaagt gatgacctat catgaggaaa tgaaagtggc   2100

tgatttgctg gtaggatttt gtacagttta gagaagcgat tatttattgt gaaactgttc   2160

tccactccaa ctcctttatg tggatctgtt caaagtagtc actgtatata cgtatagaga   2220

ggtagatagg taggtagatt ttaaattgca ttctgaatac aaactcatac tccttagagc   2280

ttgaattaca tttttaaaat gcatatgtgc tgtttggcac cgtggcaaga tggtatcaga   2340

gagaaaccca tcaattgctc aaatactcag aaagtactgt caaaagccta ataaaaaacc   2400

taaagtttgc tctga                                                    2415


<210>  10222
<211>  238
<212>  PRT
<213>  Homo sapiens

<400>  10222

Met Glu Pro Gly Leu Trp Leu Leu Phe Gly Leu Thr Val Thr Ser Ala 
1               5                   10                  15


Ala Gly Phe Val Pro Cys Ser Gln Ser Gly Asp Ala Gly Arg Arg Gly 
            20                  25                  30


Val Ser Gln Ala Pro Thr Ala Ala Arg Ser Glu Gly Asp Cys Glu Glu 
        35                  40                  45


Thr Val Ala Gly Pro Gly Glu Glu Thr Val Ala Gly Pro Gly Glu Gly 
    50                  55                  60


Thr Val Ala Pro Thr Ala Leu Gln Gly Pro Ser Pro Gly Ser Pro Gly 
65                  70                  75                  80


Gln Glu Gln Ala Ala Glu Gly Ala Pro Glu His His Arg Ser Arg Arg 
                85                  90                  95


Cys Thr Cys Phe Thr Tyr Lys Asp Lys Glu Cys Val Tyr Tyr Cys His 
            100                 105                 110


Leu Asp Ile Ile Trp Ile Asn Thr Pro Glu Gln Thr Val Pro Tyr Gly 
        115                 120                 125


Leu Ser Asn Tyr Arg Gly Ser Phe Arg Gly Lys Arg Ser Ala Gly Pro 
    130                 135                 140


Leu Pro Gly Asn Leu Gln Leu Ser His Arg Pro His Leu Arg Cys Ala 
145                 150                 155                 160


Cys Val Gly Arg Tyr Asp Lys Ala Cys Leu His Phe Cys Thr Gln Thr 
                165                 170                 175


Leu Asp Val Ser Ser Asn Ser Arg Thr Ala Glu Lys Thr Asp Lys Glu 
            180                 185                 190


Glu Glu Gly Lys Val Glu Val Lys Asp Gln Gln Ser Lys Gln Ala Leu 
        195                 200                 205


Asp Leu His His Pro Lys Leu Met Pro Gly Ser Gly Leu Ala Leu Ala 
    210                 215                 220


Pro Ser Thr Cys Pro Arg Cys Leu Phe Gln Glu Gly Ala Pro 
225                 230                 235


<210>  10223
<211>  620
<212>  DNA
<213>  Homo sapiens

<400>  10223
agactcacaa agtgtcactg ctgagcgggc tccacagcac tgcctctcat gcattcatgc     60

actcacgtga cctactccgt gccaggccag gggctcggtg tggagatgca gggctggaag    120

agcacatcct ggtgcagcag gcagttcgta agcaggaatt caaatctcct ctgtgccttt    180

gcaaagcaac atccatcttg aacataaatg aggttctggc ttgatttctg ggcttgggca    240

tcagacatct cccttttgcg gacacctaca gctctgttct tgaattttgt gattgcggat    300

aagcacccgc tccttctttt taagtccttt ggcagatagt cattcatgct tacaggatga    360

cccaggcaaa gctaaacaca gatctgggct ccaatcccac catggctgtg tgacctagtg    420

gaagttcctt aacctctctg agcctcagct ttcttttcca cagattgctg attaaaacac    480

ttactttagt gttaacacaa gggaaagctg ggcgtggagg tctatgagaa ttctctatac    540

tatttttgca actcttttgt gaatatgaaa taatctaaac tagaagattt aaaaaaaaaa    600

acaaacccaa acacgtgctt                                                620


<210>  10224
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  10224

Met His Ser Arg Asp Leu Leu Arg Ala Arg Pro Gly Ala Arg Cys Gly 
1               5                   10                  15


Asp Ala Gly Leu Glu Glu His Ile Leu Val Gln Gln Ala Val Arg Lys 
            20                  25                  30


Gln Glu Phe Lys Ser Pro Leu Cys Leu Cys Lys Ala Thr Ser Ile Leu 
        35                  40                  45


Asn Ile Asn Glu Val Leu Ala 
    50                  55


<210>  10225
<211>  630
<212>  DNA
<213>  Homo sapiens

<400>  10225
atggggagca tggcctctgt gaagaagctg caggtggctg gtttggctgg tctcaaggcc     60

atgcctaggg gtcacaaggt gttgctgttg atctgcccca gggccagata ctgggacttg    120

ggagctgaag ccaaggctga ctccaagatg ctctgtgcat ctcaaaaccc agccctcaga    180

gccatgagct gtaccagcac ctccatatct gttcccgtcg aaggggaggg tatcaccatc    240

gcccgagtca cccacatcac aagcccaggc cccatctcgg acccctccac catgttctgc    300

cagtgtggtg tccactgctc ttcctttgca ccccactgcc tcatctcaga cctggatgat    360

ggccacagcc ttttagttcc agatgccagg gtgtgggccg agggggtcac actggtcacg    420

ggcaagtcca tgtgcagctt cttcagcgag atctcacact ccatcacact ggaggagctg    480

ccatgcaggg accacatcct caagctctgc caggacatct tcctggcgtg cgagacccat    540

gagctggagc tggaggagga gctgtctgcc aagctcatct tcctctatcg ctcactggag    600

accatgatca agtggactcg tgaggagtag                                     630


<210>  10226
<211>  209
<212>  PRT
<213>  Homo sapiens

<400>  10226

Met Gly Ser Met Ala Ser Val Lys Lys Leu Gln Val Ala Gly Leu Ala 
1               5                   10                  15


Gly Leu Lys Ala Met Pro Arg Gly His Lys Val Leu Leu Leu Ile Cys 
            20                  25                  30


Pro Arg Ala Arg Tyr Trp Asp Leu Gly Ala Glu Ala Lys Ala Asp Ser 
        35                  40                  45


Lys Met Leu Cys Ala Ser Gln Asn Pro Ala Leu Arg Ala Met Ser Cys 
    50                  55                  60


Thr Ser Thr Ser Ile Ser Val Pro Val Glu Gly Glu Gly Ile Thr Ile 
65                  70                  75                  80


Ala Arg Val Thr His Ile Thr Ser Pro Gly Pro Ile Ser Asp Pro Ser 
                85                  90                  95


Thr Met Phe Cys Gln Cys Gly Val His Cys Ser Ser Phe Ala Pro His 
            100                 105                 110


Cys Leu Ile Ser Asp Leu Asp Asp Gly His Ser Leu Leu Val Pro Asp 
        115                 120                 125


Ala Arg Val Trp Ala Glu Gly Val Thr Leu Val Thr Gly Lys Ser Met 
    130                 135                 140


Cys Ser Phe Phe Ser Glu Ile Ser His Ser Ile Thr Leu Glu Glu Leu 
145                 150                 155                 160


Pro Cys Arg Asp His Ile Leu Lys Leu Cys Gln Asp Ile Phe Leu Ala 
                165                 170                 175


Cys Glu Thr His Glu Leu Glu Leu Glu Glu Glu Leu Ser Ala Lys Leu 
            180                 185                 190


Ile Phe Leu Tyr Arg Ser Leu Glu Thr Met Ile Lys Trp Thr Arg Glu 
        195                 200                 205


Glu 



<210>  10227
<211>  549
<212>  DNA
<213>  Homo sapiens

<400>  10227
atggggagca tggcctctgt gaagaagctg caggtggctg gagctgaagc caaggctgac     60

tccaagatgc tctgtgcatc tcaaaaccca gccctcagag ccatgagctg taccagcacc    120

tccatatctg ttcccgtcga aggggagggt atcaccatcg cccgagtcac ccacatcaca    180

agcccaggcc ccatctcgga cccctccacc atgttctgcc agtgtggtgt ccactgctct    240

tcctttgcac cccactgcct catctcagac ctggatgatg gccacagcct tttagttcca    300

gatgccaggg tgtgggccga gggggtcaca ctggtcacgg gcaagtccat gtgcagcttc    360

ttcagcgaga tctcacactc catcacactg gaggagctgc catgcaggga ccacatcctc    420

aagctctgcc aggacatctt cctggcgtgc gagacccatg agctggagct ggaggaggag    480

ctgtctgcca agctcatctt cctctatcgc tcactggaga ccatgatcaa gtggactcgt    540

gaggagtag                                                            549


<210>  10228
<211>  182
<212>  PRT
<213>  Homo sapiens

<400>  10228

Met Gly Ser Met Ala Ser Val Lys Lys Leu Gln Val Ala Gly Ala Glu 
1               5                   10                  15


Ala Lys Ala Asp Ser Lys Met Leu Cys Ala Ser Gln Asn Pro Ala Leu 
            20                  25                  30


Arg Ala Met Ser Cys Thr Ser Thr Ser Ile Ser Val Pro Val Glu Gly 
        35                  40                  45


Glu Gly Ile Thr Ile Ala Arg Val Thr His Ile Thr Ser Pro Gly Pro 
    50                  55                  60


Ile Ser Asp Pro Ser Thr Met Phe Cys Gln Cys Gly Val His Cys Ser 
65                  70                  75                  80


Ser Phe Ala Pro His Cys Leu Ile Ser Asp Leu Asp Asp Gly His Ser 
                85                  90                  95


Leu Leu Val Pro Asp Ala Arg Val Trp Ala Glu Gly Val Thr Leu Val 
            100                 105                 110


Thr Gly Lys Ser Met Cys Ser Phe Phe Ser Glu Ile Ser His Ser Ile 
        115                 120                 125


Thr Leu Glu Glu Leu Pro Cys Arg Asp His Ile Leu Lys Leu Cys Gln 
    130                 135                 140


Asp Ile Phe Leu Ala Cys Glu Thr His Glu Leu Glu Leu Glu Glu Glu 
145                 150                 155                 160


Leu Ser Ala Lys Leu Ile Phe Leu Tyr Arg Ser Leu Glu Thr Met Ile 
                165                 170                 175


Lys Trp Thr Arg Glu Glu 
            180


<210>  10229
<211>  3337
<212>  DNA
<213>  Homo sapiens

<400>  10229
ggcggggcct cggcggggcg gccgcggctt cacctgcagc tccgagcgcg cggaacagag     60

gcgcgggcgg ctgcgaggcc ggcggacgca ccggcccgag ggaacgcgcc gccggccgga    120

cttggcctgg ctcccggagc cggggcggcg agcgcggcgg gcgcagcggg gctggaggct    180

ccgggcaggc gcgggggagc ggcggcggcg gcggcgatcg gagcggcggc ggtggtctcg    240

gcggcggcgg cggcggcggc ggcagggagc gggctcccgg tgccgggcac cgggcgggcg    300

gcggggaaga tgaccgcggg cgccggcgtg ctccttctgc tgctctcgct ctccggcgcg    360

ctccgggccc ataatgagga tcttacaact agagagacct gcaaggctgg gttctctgaa    420

gatgattaca cggcattaat ctcccaaaat attctagaag gggaaaagct acttcaagtc    480

aagttcagca gctgtgtggg gaccaagggg acacaatatg agaccaacag catggacttc    540

aaagttgggg cagatgggac agtcttcgcc acccgggagc tgcaggtccc ctccgagcag    600

gtggcgttca cggtgactgc atgggacagc cagacagcag agaaatggga cgccgtggtg    660

cggttgctgg tggcccagac ctcgtccccg cactctggac acaagccgca gaaaggaaag    720

aaggtcgtgg ctctggaccc ctctccgcct ccgaaggaca ccctgctgcc gtggccccag    780

caccagaacg ccaacgggct gaggcggcgc aaacgggact gggtcatccc gcccatcaac    840

gtgcccgaga actcgcgcgg gcccttcccg cagcagctcg tgaggatccg gtccgacaaa    900

gacaatgaca tccccatccg gtacagcatc acgggagtgg gcgccgacca gccccccatg    960

gaggtcttca gcattgactc catgtccggc cggatgtacg tcacaaggcc catggaccgg   1020

gaggagcacg cctcttacca cctccgagcc cacgctgtgg acatgaatgg caacaaggtg   1080

gagaacccca tcgacctgta catctacgtc atcgacatga atgacaaccg ccctgagttc   1140

atcaaccagg tctacaacgg ctccgtggac gagggctcca agccaggcac ctacgtgatg   1200

accgtcacgg ccaacgatgc tgacgacagc accacggcca acgggatggt gcggtaccgg   1260

atcgtgaccc agaccccaca gagcccgtcc cagaatatgt tcaccatcaa cagcgagact   1320

ggagatatcg tcacagtggc ggctggcctg gaccgagaga aagttcagca gtacacagtc   1380

atcgttcagg ccacagatat ggaaggaaat ctcaactatg gcctctcaaa cacagccaca   1440

gccatcatca cggtgacaga tgtgaatgac aacccgccag aatttaccgc cagcacgttt   1500

gcaggggagg tccccgaaaa ccgcgtggag accgtggtcg caaacctcac ggtgatggac   1560

cgagatcagc cccactctcc aaactggaat gccgtttacc gcatcatcag tggggatcca   1620

tccgggcact tcagcgtccg cacagacccc gtaaccaacg agggcatggt caccgtggtg   1680

aaggcagtcg actacgagct caacagagct ttcatgctga cagtgatggt gtccaaccag   1740

gcgcccctgg ccagcggaat ccagatgtcc ttccagtcca cggcaggggt gaccatctcc   1800

atcatggaca tcaacgaggc tccctacttc ccctcaaacc acaagctgat ccgcctggag   1860

gagggcgtgc cccccggcac cgtgctgacc acgttttcag ctgtggaccc tgaccggttc   1920

atgcagcagg ctgtgagata ctcaaagctg tcagacccag cgagctggct gcacatcaat   1980

gccaccaacg gccagatcac cacggcggca gtgctggacc gtgagtccct ctacaccaaa   2040

aacaacgtct acgaggccac cttcctggca gctgacaatg ggataccccc ggccagcggc   2100

accgggaccc tccagatcta tctcattgac atcaacgaca acgcccctga gctgctgccc   2160

aaggaggcgc agatctgcga gaagcccaac ctgaacgcca tcaacatcac ggcggccgac   2220

gctgacgtcg accccaacat cggcccctac gtcttcgagc tgccctttgt cccggcggcc   2280

gtgcggaaga actggaccat cacccgcctg aacggtgact atgcccaact cagcttgcgc   2340

atcctgtacc tggaggccgg gatgtatgac gtccccatca tcgtcacaga ctctggaaac   2400

cctcccctgt ccaacacgtc catcatcaaa gtcaaggtgt gcccatgtga tgacaacggg   2460

gactgcacca ccattggcgc agtggcagcg gctggtctgg gcaccggtgc catcgtggcc   2520

atcctcatct gcatcctcat cctgctgacc atggtcctgc tgtttgtcat gtggatgaag   2580

cggcgagaga aggagcgcca cacgaagcag ctgctcattg accccgagga cgacgtccgc   2640

gacaacatcc tcaagtatga cgaggaaggc ggtggcgagg aggaccagga ctacgacctc   2700

agccagctgc agcagccgga agccatgggg cacgtgccaa gcaaagcccc tggcgtgcgt   2760

cgcgtggatg agcggccggt gggcgctgag ccccagtacc cgatcaggcc catggtgccg   2820

cacccaggcg acatcggtga cttcatcaat gagggactcc gcgctgctga caacgacccc   2880

acggcacccc cctatgactc cctgctggtc ttcgactacg aggggagcgg ctccaccgca   2940

ggctccgtca gctccctgaa ctcatccagt tccggggacc aagactacga ttacctcaac   3000

gactgggggc ccagattcaa gaagctggcg gacatgtatg gaggtggtga agaggattga   3060

ctgacctcgc atcttcggac cgaagtgaga gccgtgctcg gacgccggag gagcaggact   3120

gagcagaggc ggccggtctt cccgactccc tgcggctgtg tccttagtgc tgttaggagg   3180

ccccccaatc cccacgttga gctgtctagc atgagcaccc acccccacag cgccctgcac   3240

ccggccgctg cccagcaccg cgctggctgg cactgaagga cagcaagagg cactctgtct   3300

tcacttgaat ttcctagaac agaagcactg tttttaa                            3337


<210>  10230
<211>  916
<212>  PRT
<213>  Homo sapiens

<400>  10230

Met Thr Ala Gly Ala Gly Val Leu Leu Leu Leu Leu Ser Leu Ser Gly 
1               5                   10                  15


Ala Leu Arg Ala His Asn Glu Asp Leu Thr Thr Arg Glu Thr Cys Lys 
            20                  25                  30


Ala Gly Phe Ser Glu Asp Asp Tyr Thr Ala Leu Ile Ser Gln Asn Ile 
        35                  40                  45


Leu Glu Gly Glu Lys Leu Leu Gln Val Lys Phe Ser Ser Cys Val Gly 
    50                  55                  60


Thr Lys Gly Thr Gln Tyr Glu Thr Asn Ser Met Asp Phe Lys Val Gly 
65                  70                  75                  80


Ala Asp Gly Thr Val Phe Ala Thr Arg Glu Leu Gln Val Pro Ser Glu 
                85                  90                  95


Gln Val Ala Phe Thr Val Thr Ala Trp Asp Ser Gln Thr Ala Glu Lys 
            100                 105                 110


Trp Asp Ala Val Val Arg Leu Leu Val Ala Gln Thr Ser Ser Pro His 
        115                 120                 125


Ser Gly His Lys Pro Gln Lys Gly Lys Lys Val Val Ala Leu Asp Pro 
    130                 135                 140


Ser Pro Pro Pro Lys Asp Thr Leu Leu Pro Trp Pro Gln His Gln Asn 
145                 150                 155                 160


Ala Asn Gly Leu Arg Arg Arg Lys Arg Asp Trp Val Ile Pro Pro Ile 
                165                 170                 175


Asn Val Pro Glu Asn Ser Arg Gly Pro Phe Pro Gln Gln Leu Val Arg 
            180                 185                 190


Ile Arg Ser Asp Lys Asp Asn Asp Ile Pro Ile Arg Tyr Ser Ile Thr 
        195                 200                 205


Gly Val Gly Ala Asp Gln Pro Pro Met Glu Val Phe Ser Ile Asp Ser 
    210                 215                 220


Met Ser Gly Arg Met Tyr Val Thr Arg Pro Met Asp Arg Glu Glu His 
225                 230                 235                 240


Ala Ser Tyr His Leu Arg Ala His Ala Val Asp Met Asn Gly Asn Lys 
                245                 250                 255


Val Glu Asn Pro Ile Asp Leu Tyr Ile Tyr Val Ile Asp Met Asn Asp 
            260                 265                 270


Asn Arg Pro Glu Phe Ile Asn Gln Val Tyr Asn Gly Ser Val Asp Glu 
        275                 280                 285


Gly Ser Lys Pro Gly Thr Tyr Val Met Thr Val Thr Ala Asn Asp Ala 
    290                 295                 300


Asp Asp Ser Thr Thr Ala Asn Gly Met Val Arg Tyr Arg Ile Val Thr 
305                 310                 315                 320


Gln Thr Pro Gln Ser Pro Ser Gln Asn Met Phe Thr Ile Asn Ser Glu 
                325                 330                 335


Thr Gly Asp Ile Val Thr Val Ala Ala Gly Leu Asp Arg Glu Lys Val 
            340                 345                 350


Gln Gln Tyr Thr Val Ile Val Gln Ala Thr Asp Met Glu Gly Asn Leu 
        355                 360                 365


Asn Tyr Gly Leu Ser Asn Thr Ala Thr Ala Ile Ile Thr Val Thr Asp 
    370                 375                 380


Val Asn Asp Asn Pro Pro Glu Phe Thr Ala Ser Thr Phe Ala Gly Glu 
385                 390                 395                 400


Val Pro Glu Asn Arg Val Glu Thr Val Val Ala Asn Leu Thr Val Met 
                405                 410                 415


Asp Arg Asp Gln Pro His Ser Pro Asn Trp Asn Ala Val Tyr Arg Ile 
            420                 425                 430


Ile Ser Gly Asp Pro Ser Gly His Phe Ser Val Arg Thr Asp Pro Val 
        435                 440                 445


Thr Asn Glu Gly Met Val Thr Val Val Lys Ala Val Asp Tyr Glu Leu 
    450                 455                 460


Asn Arg Ala Phe Met Leu Thr Val Met Val Ser Asn Gln Ala Pro Leu 
465                 470                 475                 480


Ala Ser Gly Ile Gln Met Ser Phe Gln Ser Thr Ala Gly Val Thr Ile 
                485                 490                 495


Ser Ile Met Asp Ile Asn Glu Ala Pro Tyr Phe Pro Ser Asn His Lys 
            500                 505                 510


Leu Ile Arg Leu Glu Glu Gly Val Pro Pro Gly Thr Val Leu Thr Thr 
        515                 520                 525


Phe Ser Ala Val Asp Pro Asp Arg Phe Met Gln Gln Ala Val Arg Tyr 
    530                 535                 540


Ser Lys Leu Ser Asp Pro Ala Ser Trp Leu His Ile Asn Ala Thr Asn 
545                 550                 555                 560


Gly Gln Ile Thr Thr Ala Ala Val Leu Asp Arg Glu Ser Leu Tyr Thr 
                565                 570                 575


Lys Asn Asn Val Tyr Glu Ala Thr Phe Leu Ala Ala Asp Asn Gly Ile 
            580                 585                 590


Pro Pro Ala Ser Gly Thr Gly Thr Leu Gln Ile Tyr Leu Ile Asp Ile 
        595                 600                 605


Asn Asp Asn Ala Pro Glu Leu Leu Pro Lys Glu Ala Gln Ile Cys Glu 
    610                 615                 620


Lys Pro Asn Leu Asn Ala Ile Asn Ile Thr Ala Ala Asp Ala Asp Val 
625                 630                 635                 640


Asp Pro Asn Ile Gly Pro Tyr Val Phe Glu Leu Pro Phe Val Pro Ala 
                645                 650                 655


Ala Val Arg Lys Asn Trp Thr Ile Thr Arg Leu Asn Gly Asp Tyr Ala 
            660                 665                 670


Gln Leu Ser Leu Arg Ile Leu Tyr Leu Glu Ala Gly Met Tyr Asp Val 
        675                 680                 685


Pro Ile Ile Val Thr Asp Ser Gly Asn Pro Pro Leu Ser Asn Thr Ser 
    690                 695                 700


Ile Ile Lys Val Lys Val Cys Pro Cys Asp Asp Asn Gly Asp Cys Thr 
705                 710                 715                 720


Thr Ile Gly Ala Val Ala Ala Ala Gly Leu Gly Thr Gly Ala Ile Val 
                725                 730                 735


Ala Ile Leu Ile Cys Ile Leu Ile Leu Leu Thr Met Val Leu Leu Phe 
            740                 745                 750


Val Met Trp Met Lys Arg Arg Glu Lys Glu Arg His Thr Lys Gln Leu 
        755                 760                 765


Leu Ile Asp Pro Glu Asp Asp Val Arg Asp Asn Ile Leu Lys Tyr Asp 
    770                 775                 780


Glu Glu Gly Gly Gly Glu Glu Asp Gln Asp Tyr Asp Leu Ser Gln Leu 
785                 790                 795                 800


Gln Gln Pro Glu Ala Met Gly His Val Pro Ser Lys Ala Pro Gly Val 
                805                 810                 815


Arg Arg Val Asp Glu Arg Pro Val Gly Ala Glu Pro Gln Tyr Pro Ile 
            820                 825                 830


Arg Pro Met Val Pro His Pro Gly Asp Ile Gly Asp Phe Ile Asn Glu 
        835                 840                 845


Gly Leu Arg Ala Ala Asp Asn Asp Pro Thr Ala Pro Pro Tyr Asp Ser 
    850                 855                 860


Leu Leu Val Phe Asp Tyr Glu Gly Ser Gly Ser Thr Ala Gly Ser Val 
865                 870                 875                 880


Ser Ser Leu Asn Ser Ser Ser Ser Gly Asp Gln Asp Tyr Asp Tyr Leu 
                885                 890                 895


Asn Asp Trp Gly Pro Arg Phe Lys Lys Leu Ala Asp Met Tyr Gly Gly 
            900                 905                 910


Gly Glu Glu Asp 
        915


<210>  10231
<211>  637
<212>  DNA
<213>  Homo sapiens

<400>  10231
cgtttttgct gcgtcacagg gagacagaag atgggctgct atttcgtcgg ctaaatgcta     60

tcattttaag caccgttcca aagaaaacag ggatcttgcc agaggaaaat aacatatacc    120

ataaaggaaa aagaaatgtg catcaaggca aataaacagc tctctactaa gggcctagga    180

tcttgctaga cgagtcattt ctctggttga aaagcagttg agaaaggcaa gacaaggggg    240

gcgggggccc agcagggcac ctctgagccc ttcctgctgc tcttcaaaga cagacgcatt    300

ttcctttcta cggtctcctt gcaagtcttc tgtaggccct gccaccttca ggctgactga    360

ctgcctcctt caaatatcag catttggggc cccatgaagg caggcagccc agggaggaat    420

gactggacgg tgacattgtg cagggggtct ggaagttgcc agcgcagggg ttagcagctg    480

cagcctggcc tggtcctgtc tgcctggctg tcaaacccag aagaccgtgg tttctggtgg    540

cctctgtgtg acagcggagg aggtggggcg aggcctggaa gtgaagcatc tcgtgagcca    600

cttaagtgtt tatgaagctc gctaatgtgc ttaaatg                             637


<210>  10232
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  10232

Asp Leu Ala Arg Arg Val Ile Ser Leu Val Glu Lys Gln Leu Arg Lys 
1               5                   10                  15


Ala Arg Gln Gly Gly Arg Gly Pro Ser Arg Ala Pro Leu Ser Pro Ser 
            20                  25                  30


Cys Cys Ser Ser Lys Thr Asp Ala Phe Ser Phe Leu Arg Ser Pro Cys 
        35                  40                  45


Lys Ser Ser Val Gly Pro Ala Thr Phe Arg Leu Thr Asp Cys Leu Leu 
    50                  55                  60


Gln Ile Ser Ala Phe Gly Ala Pro 
65                  70


<210>  10233
<211>  663
<212>  DNA
<213>  Homo sapiens

<400>  10233
gattacaact gctcttagga tgaagtgact ggagcccaga taccttattt agcaatcagt     60

gctcggcaca aggacttgct gtgccaacga aaaggaagcg aggcattttg gctagtcacc    120

gcgtttttgc tgcgtcacag ggagacagaa gatgggctgc tatttcgtcg gctaaatgct    180

atcattttaa gcaccgttcc aaagaaaaca gggatcttgc cagaggaaaa taacatatac    240

cataaaggaa aaagaaatgt gcatcaaggc aaataaacag ctctctacta agggcctagg    300

atcttgctag acgagtcatt tctctggttg aaaagcagtt gagaaaggca agacaagggg    360

ggcgggggcc cagcagggca cctctgagcc cttcctgctg ctcttcaaag acagacgcat    420

tttcctttct acggtctcct tgcaagtctt ctgtaggccc tgccaccttc aggctgactg    480

actgcctcct tcaaatatca gcatttggaa gggtactggg gagtcgacac cctcatgtct    540

gtgagctgac tgcaggacgt ctcctgtcca ggtgctggca cctcatctaa catttgaagg    600

taaaagcagc tctggcctcc tgcaggtgca aggacccggg agccgctctg tgggctgggc    660

tca                                                                  663


<210>  10234
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  10234

Asp Leu Ala Arg Arg Val Ile Ser Leu Val Glu Lys Gln Leu Arg Lys 
1               5                   10                  15


Ala Arg Gln Gly Gly Arg Gly Pro Ser Arg Ala Pro Leu Ser Pro Ser 
            20                  25                  30


Cys Cys Ser Ser Lys Thr Asp Ala Phe Ser Phe Leu Arg Ser Pro Cys 
        35                  40                  45


Lys Ser Ser Val Gly Pro Ala Thr Phe Arg Leu Thr Asp Cys Leu Leu 
    50                  55                  60


Gln Ile Ser Ala Phe Gly Arg Val Leu Gly Ser Arg His Pro His Val 
65                  70                  75                  80


Cys Glu Leu Thr Ala Gly Arg Leu Leu Ser Arg Cys Trp His Leu Ile 
                85                  90                  95


<210>  10235
<211>  608
<212>  DNA
<213>  Homo sapiens

<400>  10235
aactgctctt aggatgaagt gactggagcc cagatacctt atttagcaat cagtgctcgg     60

cacaaggact tgctgtgcca acgaaaagga agcgaggcat tttggctagt caccgcgttt    120

ttgctgcgtc acagggagac agaagatggg ctgctatttc gtcggctaaa tgctatcatt    180

ttaagcaccg ttccaaagaa aacagggatc ttgccagagg aaaataacat ataccataaa    240

ggaaaaagaa atgtgcatca aggcaaataa acagctctct actaagggcc taggatcttg    300

ctagacgagt catttctctg gttgaaaagc agttgagaaa ggcaagacaa ggggggcggg    360

ggcccagcag ggcacctctg agcccttcct gctgctcttc aaagacagac gcattttcct    420

ttctacggtc tccttgcaag tcttctgtag gccctgccac cttcaggctg actgactgcc    480

tccttcaaat atcagcattt gatggatgtg ctggaaggag acccctgctg acccctgctg    540

actccatgac agagggatgg aaattctgcc cctcccagac ctcaccctat gcgttctgtt    600

tcctttat                                                             608


<210>  10236
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  10236

Asp Glu Val Thr Gly Ala Gln Ile Pro Tyr Leu Ala Ile Ser Ala Arg 
1               5                   10                  15


His Lys Asp Leu Leu Cys Gln Arg Lys Gly Ser Glu Ala Phe Trp Leu 
            20                  25                  30


Val Thr Ala Phe Leu Leu Arg His Arg Glu Thr Glu Asp Gly Leu Leu 
        35                  40                  45


Phe Arg Arg Leu Asn Ala Ile Ile Leu Ser Thr Val Pro Lys Lys Thr 
    50                  55                  60


Gly Ile Leu Pro Glu Glu Asn Asn Ile Tyr His Lys Gly Lys Arg Asn 
65                  70                  75                  80


Val His Gln Gly Lys 
                85


<210>  10237
<211>  3347
<212>  DNA
<213>  Homo sapiens

<400>  10237
gctaacgata aagaaagaat cagaataaaa tgtacctgcc atccagtttt ggatcttttt     60

aaaactaatg agtatgaact tgagatctgt ataaataaga gcatgatttg aaaaaaagca    120

tggtataatt gaaacttttt tcattttgaa aagtattggt tactggtgat gttgaaatat    180

gcatactaat ttttgcttaa cattagatgt catgaggaaa ctactgaact agcaattggt    240

tgtttaacac ttctgtatgc atcagataac aactgtgagt agcctatgaa tgaaattctt    300

ttataaatat taggcataaa ttaaaatgta aaactccatt catagtggat taatgcattt    360

tgctgccttt attagggtac tttattttgc ttttcagaag tcagcctaca taacacattt    420

ttaaagtcta aactgttaaa caactcttta aaggataatt atccaataaa aaaaaaccta    480

gtgctgattc acagcttatt atccaattca aaaataaatt agaaaaatat atgcttacat    540

ttttcacttt tgctaaaaag aaaaaaaaaa ggtgtttatt tttaactctt ggaagaggtt    600

ttgtggttcc caatgtgtct gtcccaccct gatccttttc aatatatatt tctttaaacc    660

ttgtgctact tagtaaaaat tgattacaat tgagggaagt ttgatagatc ctttaaaaaa    720

aaggcagatt tccatttttt gtattttaac tactttacta aattaatact cctcctttta    780

cagaattaga aaagttaaca tttatcttta ggtggtttcc tgaaaagttg aatatttaag    840

aaattgtttt taacagaagc aaaatggctt ttctttggac agttttcacc atctcttgta    900

aaagttaatt ctcaccattc ctgtggtacc tgcgagtgtt atgaccagga ttccttaaac    960

ctgaatgact tatgactttc ctcagaacat gagactgtaa aacaaaaaca aaaaactatg   1020

tgatgcctct attttcccca atacagtcac acatcagctc aaaatttgca atattgtagt   1080

tcatatatta ccgttatgtc tttggaaatc gggttcagaa cactttttat gacaaaaatt   1140

gggtggaggg gataactttc atatctggct caacatctca ggaaaatctg tgattatttg   1200

tgtgttctaa tgagtaacat ctacttagtt agccttaggg atggaaaaac agggccactt   1260

accaaactca ggtgattcca ggatggtttg gaaacttctc ctgaatgcat ccttaacctt   1320

tattaaaacc attgtcctaa gaacaatgcc aacaaagctt acaacattta gtttaaaccc   1380

aagaagggca ctaaactcag attgactaaa taaaaagtac aaagggcaca tatacgtgac   1440

agaattgtac acaatcactc cattggatct tttactttaa agtagtgatg aaaagtacat   1500

gttgatactg tcttagaaga aattaatata ttagtgaagc cacatggggt ttcagttgcg   1560

aaacaggtct gtttttatgt tcagtttgta caatccacaa ttcattcacc agatattttg   1620

ttcttaattg tgaaccaggt tagcaaatga cctatcaaaa attattctat aatcactact   1680

agttaggata ttgatttaaa attgttctac ttgaagtggt ttctaagatt tttatattaa   1740

aaataggtgt gatttcctaa tatgatctaa aaccctaaat ggttattttt cctcagaatg   1800

atttgtaaat agctactgga aatattatac agtaatagga gtgggtatta tgcaacatca   1860

tggagaagtg aaggcatagg cttattctga cataaaattc cactggccag ttgaatatat   1920

tctattccat gtccatacta tgacaatctt attgtcaaca ctatataaat aagcttttaa   1980

acaagtcatt tttcttgatc gttgtggaag gtttggagcc ttagaggtat gtcagaaaaa   2040

atatgttggt attctccctt gggtaggggg aaatgacctt tttacaagag agtgaaattt   2100

aggtcaggga aaagaccaag ggccagcatt gctacttttg tgtgtgtgtg tgtgggtttt   2160

gttttgtttt tttggttggc tggttgtttt cgttgttgtt aacaaaggaa tgagaatatg   2220

taatacttaa ataaacatga ccacgaagaa tgctgttctg atttactaga gaatgttccc   2280

aatttgaatt tagggtgatt ttaaagaaca gtgagaaagg gcatacatcc acagattcac   2340

tttgtttatg catatgtaga tacaaggatg cacatataca cattttcaag gactatttta   2400

gatatctaga caatttcttc taataaagtc atttgtgaaa gggtactaca gcttattgac   2460

atcagtaagg tagcattcat tacctgttta ttctctgctg catcttacag aagagtaaac   2520

tggtgagagt atatatttta tatatatata tatatatata tatataatat gtatatatat   2580

atatattgac ttgttacatg aagatgttaa aatcggtttt taaaggtgat gtaaatagtg   2640

atttccttaa tgaaaaatac atattttgta ttgttctaat gcaacagaaa agccttttaa   2700

tctctttggt tcctgtatat tccatgtata agtgtaaata taatcagaca ggtttaaaag   2760

ttgtgcatgt atgtatacag ttgcaagtct ggacaaatgt atagaataaa ccttttattt   2820

aagttgtgat tacctgctgc atgaaaagtg catgggggac cctgtgcatc tgtgcatttg   2880

gcaaaatgtc ttaacaaatc agatcagatg ttcatcctaa catgacagta ttccatttct   2940

ggacatgacg tctgtggttt aagctttgtg aaagaatgtg ctttgattcg aagggtctta   3000

aagaattttt ttaatcgtca accactttta aacataaaga attcacacaa ctactttcat   3060

gaatttttta atcccattgc aaacattatt ccaagagtat cccagtatta gcaatactgg   3120

aatataggca cattaccatt catagtaaga attctggtgt ttacacaacc aaatttgatg   3180

cgatctgctc agtaatataa tttgccattt ttattagaaa tttaatttct tcatgtgatg   3240

tcatgaaact gtacatactg cagtgtgaat ttttttgttt tgttttttaa tcttttagtg   3300

tttacttcct gcagtgaatt tgaataaatg agaaaaaatg cattgtc                 3347


<210>  10238
<211>  68
<212>  PRT
<213>  Homo sapiens

<400>  10238

Met Lys Met Leu Lys Ser Val Phe Lys Gly Asp Val Asn Ser Asp Phe 
1               5                   10                  15


Leu Asn Glu Lys Tyr Ile Phe Cys Ile Val Leu Met Gln Gln Lys Ser 
            20                  25                  30


Leu Leu Ile Ser Leu Val Pro Val Tyr Ser Met Tyr Lys Cys Lys Tyr 
        35                  40                  45


Asn Gln Thr Gly Leu Lys Val Val His Val Cys Ile Gln Leu Gln Val 
    50                  55                  60


Trp Thr Asn Val 
65


<210>  10239
<211>  1325
<212>  DNA
<213>  Homo sapiens

<400>  10239
agggaggctt catctgctga aagtgtctca caggtcacag ccaaagaaga gttacttcct     60

actgcagaaa cgaaagcttc tttctttaat ttaagaagcc cttacaatag ccatatggga    120

aataatgctt ctcgcccaca cagcgcaaat ggagaagttt atggacttct gggaagcgtg    180

ctaacgataa agaaagaatc agaataaaat gtacctgcca tccagttttg gatcttttta    240

aaactaatga gtatgaactt gagatctgta taaataagag catgatttga aaaaaagcat    300

ggtataattg aaactttttt cattttgaaa agtattggtt actggtgatg ttgaaatatg    360

catactaatt tttgcttaac attagatgtc atgaggaaac tactgaacta gcaattggtt    420

gtttaacact tctgtatgca tcagataaca actgtgagta gcctatgaat gaaattcttt    480

tataaatatt aggcataaat taaaatgtaa aactccattc atagtggatt aatgcatttt    540

gctgccttta ttagggtact ttattttgct tttcagaagt cagcctacat aacacatttt    600

taaagtctaa actgttaaac aactctttaa aggataatta tccaataaaa aaaaacctag    660

tgctgattca cagcttatta tccaattcaa aaataaatta gaaaaatata tgcttacatt    720

tttcactttt gctaaaaaga aaaaaaaaag gtgtttattt ttaactcttg gaagaggttt    780

tgtggttccc aatgtgtctg tcccaccctg atccttttca atatatattt ctttaaaccc    840

tgtgcatctg tgcatttggc aaaatgtctt aacaaatcag atcagatgtt catcctaaca    900

tgacagtatt ccatttctgg acatgacgtc tgtggtttaa gctttgtgaa agaatgtgct    960

ttgattcgaa gggtcttaaa gaattttttt aatcgtcaac cacttttaaa cataaagaat   1020

tcacacaact actttcatga attttttaat cccattgcaa acattattcc aagagtatcc   1080

cagtattagc aatactggaa tataggcaca ttaccattca tagtaagaat tctggtgttt   1140

acacaaccaa atttgatgcg atctgctcag taatataatt tgccattttt attagaaatt   1200

taatttcttc atgtgatgtc atgaaactgt acatactgca gtgtgaattt ttttgttttg   1260

ttttttaatc ttttagtgtt tacttcctgc agtgaatttg aataaatgag aaaaaatgca   1320

ttgtc                                                               1325


<210>  10240
<211>  33
<212>  PRT
<213>  Homo sapiens

<400>  10240

Met Leu Thr Phe Phe Thr Phe Ala Lys Lys Lys Lys Lys Arg Cys Leu 
1               5                   10                  15


Phe Leu Thr Leu Gly Arg Gly Phe Val Val Pro Asn Val Ser Val Pro 
            20                  25                  30


Pro 



<210>  10241
<211>  7292
<212>  DNA
<213>  Homo sapiens

<400>  10241
aacactgata tttgcattta atggggaaca aaagatgaag aaggaaaagg aatatattca     60

ctaaggattc tatctgctta ctgctacaga cctatgtgtt aaggaattct tctcctcctc    120

cttgcgtaga agttgatcag cactgtggtc agactgcatt tatcttgtca ttgccagaag    180

aaatcttgga cagaatgtaa cagtacgtct ctctctgatt gcgatggaag gtgataaact    240

gatactcctt tattaaagtt acatcgcact caccacagaa aaccattctt taaagtgaat    300

agaaaccaag cccttgtgaa cacttctatt gaacatgact catggagaag agcttggctc    360

tgatgtgcac caggattcta ttgttttaac ttacctagaa ggattactaa tgcatcaggc    420

agcaggggga tcaggtactg ccgttgacaa aaagtctgct gggcataatg aagaggatca    480

gaactttaac atttctggca gtgcatttcc cacctgtcaa agtaatggtc cagttctcaa    540

tacacataca tatcaggggt ctggcatgct gcacctcaaa aaagccagac tgttgcagtc    600

ttctgaggac tggaatgcag caaagcggaa gaggctgtct gattctatca tgaatttaaa    660

cgtaaagaag gaagctttgc tagctggcat ggttgacagt gtgcctaaag gcaaacagga    720

tagcacatta ctggcctctt tgcttcagtc attcagctct aggctgcaga ctgttgctct    780

gtcacaacaa atcaggcaga gcctcaagga gcaaggatat gccctcagtc atgattcttt    840

aaaagtggag aaggatttaa ggtgctatgg tgttgcatca agtcacttaa aaactttgtt    900

gaagaaaagt aaagttaaag atcaaaagcc tgatacgaat cttcctgatg tgactaaaaa    960

cctcatcaga gataggtttg cagagtctcc tcatcatgtt ggacaaagtg gaacaaaggt   1020

catgagtgaa ccgttgtcat gtgctgcaag attacaggct gttgcaagca tggtggaaaa   1080

aagggctagt cctgccacct cacctaaacc tagtgttgct tgtagccagt tagcattact   1140

tctgtcaagc gaagcccatt tgcagcagta ttctcgagaa cacgctttaa aaacgcaaaa   1200

tgcaaatcaa gcagcaagtg aaagacttgc tgctatggcc agattgcaag aaaatggcca   1260

gaaggatgtt ggcagttacc agctcccaaa aggaatgtca agccatctta atggtcaggc   1320

aagaacatca tcaagcaaac tgatggctag caaaagtagt gctacagtgt ttcaaaatcc   1380

aatgggtatc attccttctt cccctaaaaa tgcaggttat aagaactcac tggaaagaaa   1440

caatataaaa caagctgcta acaatagttt gcttttacat cttcttaaaa gccagactat   1500

acctaagcca atgaatggac acagtcacag tgagagagga agcatttttg aggaaagtag   1560

tacacctaca actattgatg aatattcaga taacaatcct agttttacag atgacagcag   1620

tggtgatgaa agttcttatt ccaactgtgt tcccatagac ttgtcttgca aacaccgaac   1680

tgaaaaatca gaatctgacc aacctgtttc cctggataac ttcactcaat ccttgctaaa   1740

cacttgggat ccaaaagtcc cagatgtaga tatcaaagaa gatcaagata cctcaaagaa   1800

ttctaagcta aactcacacc agaaagtaac acttcttcaa ttgctacttg gccataagaa   1860

tgaagaaaat gtagaaaaaa acaccagccc tcagggagta cacaatgatg tgagcaagtt   1920

caatacacaa aattatgcaa ggacttctgt gatagaaagc cccagtacaa atcggactac   1980

tccagtgagc actccacctt tacttacatc aagcaaagca gggtctccca tcaatctctc   2040

tcaacactct ctggtcatca aatggaattc cccaccatat gtctgcagta ctcagtctga   2100

aaagctaaca aatactgcat ctaaccactc aatggacctt acaaaaagca aagacccacc   2160

aggagagaaa ccagcccaaa atgaaggtgc acagaactct gcaacgttta gtgccagtaa   2220

gctgttacaa aatttagcac aatgtggaat gcagtcatcc atgtcagtgg aagagcagag   2280

acccagcaaa cagctgttaa ctggaaacac agataaaccg ataggtatga ttgatagatt   2340

aaatagccct ttgctctcaa ataaaacaaa tgcagttgaa gaaaataaag catttagtag   2400

tcaaccaaca ggtcctgaac cagggctttc tggttctgaa atagaaaatc tgcttgaaag   2460

acgtactgtc ctccagttgc tcctggggaa ccccaacaaa gggaagagtg aaaaaaaaga   2520

gaaaactccc ttaagagatg aaagtactca ggaacactca gagagagctt taagtgaaca   2580

aatactgatg gtgaaaataa aatctgagcc ttgtgatgac ttacaaattc ctaacacaaa   2640

tgtgcacttg agccatgatg ctaagagtgc cccattcttg ggtatggctc ctgctgtgca   2700

gagaagcgca cctgccttac cagtgtccga agactttaaa tcggagcctg tttcacctca   2760

ggatttttct ttctccaaga atggtctgct aagtcgattg ctaagacaaa atcaagatag   2820

ttacctggca gatgattcag acaggagtca cagaaataat gaaatggcac ttctagaatc   2880

aaagaatctt tgcatggtcc ctaagaaaag gaagctttat actgagccat tagaaaatcc   2940

atttaaaaag atgaaaaaca acattgttga tgctgcaaac aatcacagtg ccccagaagt   3000

actgtatggg tccttgctta accaggaaga gctgaaattt agcagaaatg atcttgaatt   3060

taaatatcct gctggtcatg gctcagccag cgaaagtgaa cacaggagtt gggccagaga   3120

gagcaaaagc tttaatgttc tgaaacagct gcttctctca gaaaactgtg tgcgagattt   3180

gtccccgcac agaagtaact ctgtggctga cagtaaaaag aaaggacaca aaaataatgt   3240

gaccaacagc aaacctgaat ttagcatttc ttctttaaat ggactgatgt acagttccac   3300

tcagcccagc agttgcatgg ataacaggac attttcatac ccaggtgtag taaaaactcc   3360

tgtgagtcct actttccctg agcacttggg ctgtgcaggg tctagaccag aatctgggct   3420

tttgaatggg tgttccatgc ccagtgagaa aggacccatt aagtgggtta tcactgatgc   3480

ggagaagaat gagtatgaaa aagactctcc aagattgacc aaaaccaacc caatactata   3540

ttacatgctt caaaaaggag gcaattctgt taccagtcga gaaacacaag acaaggacat   3600

ttggagggag gcttcatctg ctgaaagtgt ctcacaggtc acagccaaag aagagttact   3660

tcctactgca gaaacgaaag cttctttctt taatttaaga agcccttaca atagccatat   3720

gggaaataat gcttctcgcc cacacagcgc aaatggagaa gtttatggac ttctgggaag   3780

cgtgctaacg ataaagaaag aatcagaata aaatgtacct gccatccagt tttggatctt   3840

tttaaaacta atgagtatga acttgagatc tgtataaata agagcatgat ttgaaaaaaa   3900

gcatggtata attgaaactt ttttcatttt gaaaagtatt ggttactggt gatgttgaaa   3960

tatgcatact aatttttgct taacattaga tgtcatgagg aaactactga actagcaatt   4020

ggttgtttaa cacttctgta tgcatcagat aacaactgtg agtagcctat gaatgaaatt   4080

cttttataaa tattaggcat aaattaaaat gtaaaactcc attcatagtg gattaatgca   4140

ttttgctgcc tttattaggg tactttattt tgcttttcag aagtcagcct acataacaca   4200

tttttaaagt ctaaactgtt aaacaactct ttaaaggata attatccaat aaaaaaaaac   4260

ctagtgctga ttcacagctt attatccaat tcaaaaataa attagaaaaa tatatgctta   4320

catttttcac ttttgctaaa aagaaaaaaa aaaggtgttt atttttaact cttggaagag   4380

gttttgtggt tcccaatgtg tctgtcccac cctgatcctt ttcaatatat atttctttaa   4440

accttgtgct acttagtaaa aattgattac aattgaggga agtttgatag atcctttaaa   4500

aaaaaggcag atttccattt tttgtatttt aactacttta ctaaattaat actcctcctt   4560

ttacagaatt agaaaagtta acatttatct ttaggtggtt tcctgaaaag ttgaatattt   4620

aagaaattgt ttttaacaga agcaaaatgg cttttctttg gacagttttc accatctctt   4680

gtaaaagtta attctcacca ttcctgtggt acctgcgagt gttatgacca ggattcctta   4740

aacctgaact cagaccactt gcattagaac catctggagc acttgtttta aaatgcagat   4800

tcataggcag catctcagat ctacagaaca agaatctctg ctaagtggac ctggaatctt   4860

ccatctgcat cttaacatgc tctctaggtg tttcttgtgt ttgagaacca tgacttatga   4920

ctttcctcag aacatgagac tgtaaaacaa aaacaaaaaa ctatgtgatg cctctatttt   4980

ccccaataca gtcacacatc agctcaaaat ttgcaatatt gtagttcata tattaccgtt   5040

atgtctttgg aaatcgggtt cagaacactt tttatgacaa aaattgggtg gaggggataa   5100

ctttcatatc tggctcaaca tctcaggaaa atctgtgatt atttgtgtgt tctaatgagt   5160

aacatctact tagttagcct tagggatgga aaaacagggc cacttaccaa actcaggtga   5220

ttccaggatg gtttggaaac ttctcctgaa tgcatcctta acctttatta aaaccattgt   5280

cctaagaaca atgccaacaa agcttacaac atttagttta aacccaagaa gggcactaaa   5340

ctcagattga ctaaataaaa agtacaaagg gcacatatac gtgacagaat tgtacacaat   5400

cactccattg gatcttttac tttaaagtag tgatgaaaag tacatgttga tactgtctta   5460

gaagaaatta atatattagt gaagccacat ggggtttcag ttgcgaaaca ggtctgtttt   5520

tatgttcagt ttgtacaatc cacaattcat tcaccagata ttttgttctt aattgtgaac   5580

caggttagca aatgacctat caaaaattat tctataatca ctactagtta ggatattgat   5640

ttaaaattgt tctacttgaa gtggtttcta agatttttat attaaaaata ggtgtgattt   5700

cctaatatga tctaaaaccc taaatggtta tttttcctca gaatgatttg taaatagcta   5760

ctggaaatat tatacagtaa taggagtggg tattatgcaa catcatggag aagtgaaggc   5820

ataggcttat tctgacataa aattccactg gccagttgaa tatattctat tccatgtcca   5880

tactatgaca atcttattgt caacactata taaataagct tttaaacaag tcatttttct   5940

tgatcgttgt ggaaggtttg gagccttaga ggtatgtcag aaaaaatatg ttggtattct   6000

cccttgggta gggggaaatg acctttttac aagagagtga aatttaggtc agggaaaaga   6060

ccaagggcca gcattgctac ttttgtgtgt gtgtgtgtgg gttttgtttt gtttttttgg   6120

ttggctggtt gttttcgttg ttgttaacaa aggaatgaga atatgtaata cttaaataaa   6180

catgaccacg aagaatgctg ttctgattta ctagagaatg ttcccaattt gaatttaggg   6240

tgattttaaa gaacagtgag aaagggcata catccacaga ttcactttgt ttatgcatat   6300

gtagatacaa ggatgcacat atacacattt tcaaggacta ttttagatat ctagacaatt   6360

tcttctaata aagtcatttg tgaaagggta ctacagctta ttgacatcag taaggtagca   6420

ttcattacct gtttattctc tgctgcatct tacagaagag taaactggtg agagtatata   6480

ttttatatat atatatatat atatatatat aatatgtata tatatatata ttgacttgtt   6540

acatgaagat gttaaaatcg gtttttaaag gtgatgtaaa tagtgatttc cttaatgaaa   6600

aatacatatt ttgtattgtt ctaatgcaac agaaaagcct tttaatctct ttggttcctg   6660

tatattccat gtataagtgt aaatataatc agacaggttt aaaagttgtg catgtatgta   6720

tacagttgca agtctggaca aatgtataga ataaaccttt tatttaagtt gtgattacct   6780

gctgcatgaa aagtgcatgg gggaccctgt gcatctgtgc atttggcaaa atgtcttaac   6840

aaatcagatc agatgttcat cctaacatga cagtattcca tttctggaca tgacgtctgt   6900

ggtttaagct ttgtgaaaga atgtgctttg attcgaaggg tcttaaagaa tttttttaat   6960

cgtcaaccac ttttaaacat aaagaattca cacaactact ttcatgaatt ttttaatccc   7020

attgcaaaca ttattccaag agtatcccag tattagcaat actggaatat aggcacatta   7080

ccattcatag taagaattct ggtgtttaca caaccaaatt tgatgcgatc tgctcagtaa   7140

tataatttgc catttttatt agaaatttaa tttcttcatg tgatgtcatg aaactgtaca   7200

tactgcagtg tgaatttttt tgttttgttt tttaatcttt tagtgtttac ttcctgcagt   7260

gaatttgaat aaatgagaaa aaatgcattg tc                                 7292


<210>  10242
<211>  1158
<212>  PRT
<213>  Homo sapiens

<400>  10242

Met Thr His Gly Glu Glu Leu Gly Ser Asp Val His Gln Asp Ser Ile 
1               5                   10                  15


Val Leu Thr Tyr Leu Glu Gly Leu Leu Met His Gln Ala Ala Gly Gly 
            20                  25                  30


Ser Gly Thr Ala Val Asp Lys Lys Ser Ala Gly His Asn Glu Glu Asp 
        35                  40                  45


Gln Asn Phe Asn Ile Ser Gly Ser Ala Phe Pro Thr Cys Gln Ser Asn 
    50                  55                  60


Gly Pro Val Leu Asn Thr His Thr Tyr Gln Gly Ser Gly Met Leu His 
65                  70                  75                  80


Leu Lys Lys Ala Arg Leu Leu Gln Ser Ser Glu Asp Trp Asn Ala Ala 
                85                  90                  95


Lys Arg Lys Arg Leu Ser Asp Ser Ile Met Asn Leu Asn Val Lys Lys 
            100                 105                 110


Glu Ala Leu Leu Ala Gly Met Val Asp Ser Val Pro Lys Gly Lys Gln 
        115                 120                 125


Asp Ser Thr Leu Leu Ala Ser Leu Leu Gln Ser Phe Ser Ser Arg Leu 
    130                 135                 140


Gln Thr Val Ala Leu Ser Gln Gln Ile Arg Gln Ser Leu Lys Glu Gln 
145                 150                 155                 160


Gly Tyr Ala Leu Ser His Asp Ser Leu Lys Val Glu Lys Asp Leu Arg 
                165                 170                 175


Cys Tyr Gly Val Ala Ser Ser His Leu Lys Thr Leu Leu Lys Lys Ser 
            180                 185                 190


Lys Val Lys Asp Gln Lys Pro Asp Thr Asn Leu Pro Asp Val Thr Lys 
        195                 200                 205


Asn Leu Ile Arg Asp Arg Phe Ala Glu Ser Pro His His Val Gly Gln 
    210                 215                 220


Ser Gly Thr Lys Val Met Ser Glu Pro Leu Ser Cys Ala Ala Arg Leu 
225                 230                 235                 240


Gln Ala Val Ala Ser Met Val Glu Lys Arg Ala Ser Pro Ala Thr Ser 
                245                 250                 255


Pro Lys Pro Ser Val Ala Cys Ser Gln Leu Ala Leu Leu Leu Ser Ser 
            260                 265                 270


Glu Ala His Leu Gln Gln Tyr Ser Arg Glu His Ala Leu Lys Thr Gln 
        275                 280                 285


Asn Ala Asn Gln Ala Ala Ser Glu Arg Leu Ala Ala Met Ala Arg Leu 
    290                 295                 300


Gln Glu Asn Gly Gln Lys Asp Val Gly Ser Tyr Gln Leu Pro Lys Gly 
305                 310                 315                 320


Met Ser Ser His Leu Asn Gly Gln Ala Arg Thr Ser Ser Ser Lys Leu 
                325                 330                 335


Met Ala Ser Lys Ser Ser Ala Thr Val Phe Gln Asn Pro Met Gly Ile 
            340                 345                 350


Ile Pro Ser Ser Pro Lys Asn Ala Gly Tyr Lys Asn Ser Leu Glu Arg 
        355                 360                 365


Asn Asn Ile Lys Gln Ala Ala Asn Asn Ser Leu Leu Leu His Leu Leu 
    370                 375                 380


Lys Ser Gln Thr Ile Pro Lys Pro Met Asn Gly His Ser His Ser Glu 
385                 390                 395                 400


Arg Gly Ser Ile Phe Glu Glu Ser Ser Thr Pro Thr Thr Ile Asp Glu 
                405                 410                 415


Tyr Ser Asp Asn Asn Pro Ser Phe Thr Asp Asp Ser Ser Gly Asp Glu 
            420                 425                 430


Ser Ser Tyr Ser Asn Cys Val Pro Ile Asp Leu Ser Cys Lys His Arg 
        435                 440                 445


Thr Glu Lys Ser Glu Ser Asp Gln Pro Val Ser Leu Asp Asn Phe Thr 
    450                 455                 460


Gln Ser Leu Leu Asn Thr Trp Asp Pro Lys Val Pro Asp Val Asp Ile 
465                 470                 475                 480


Lys Glu Asp Gln Asp Thr Ser Lys Asn Ser Lys Leu Asn Ser His Gln 
                485                 490                 495


Lys Val Thr Leu Leu Gln Leu Leu Leu Gly His Lys Asn Glu Glu Asn 
            500                 505                 510


Val Glu Lys Asn Thr Ser Pro Gln Gly Val His Asn Asp Val Ser Lys 
        515                 520                 525


Phe Asn Thr Gln Asn Tyr Ala Arg Thr Ser Val Ile Glu Ser Pro Ser 
    530                 535                 540


Thr Asn Arg Thr Thr Pro Val Ser Thr Pro Pro Leu Leu Thr Ser Ser 
545                 550                 555                 560


Lys Ala Gly Ser Pro Ile Asn Leu Ser Gln His Ser Leu Val Ile Lys 
                565                 570                 575


Trp Asn Ser Pro Pro Tyr Val Cys Ser Thr Gln Ser Glu Lys Leu Thr 
            580                 585                 590


Asn Thr Ala Ser Asn His Ser Met Asp Leu Thr Lys Ser Lys Asp Pro 
        595                 600                 605


Pro Gly Glu Lys Pro Ala Gln Asn Glu Gly Ala Gln Asn Ser Ala Thr 
    610                 615                 620


Phe Ser Ala Ser Lys Leu Leu Gln Asn Leu Ala Gln Cys Gly Met Gln 
625                 630                 635                 640


Ser Ser Met Ser Val Glu Glu Gln Arg Pro Ser Lys Gln Leu Leu Thr 
                645                 650                 655


Gly Asn Thr Asp Lys Pro Ile Gly Met Ile Asp Arg Leu Asn Ser Pro 
            660                 665                 670


Leu Leu Ser Asn Lys Thr Asn Ala Val Glu Glu Asn Lys Ala Phe Ser 
        675                 680                 685


Ser Gln Pro Thr Gly Pro Glu Pro Gly Leu Ser Gly Ser Glu Ile Glu 
    690                 695                 700


Asn Leu Leu Glu Arg Arg Thr Val Leu Gln Leu Leu Leu Gly Asn Pro 
705                 710                 715                 720


Asn Lys Gly Lys Ser Glu Lys Lys Glu Lys Thr Pro Leu Arg Asp Glu 
                725                 730                 735


Ser Thr Gln Glu His Ser Glu Arg Ala Leu Ser Glu Gln Ile Leu Met 
            740                 745                 750


Val Lys Ile Lys Ser Glu Pro Cys Asp Asp Leu Gln Ile Pro Asn Thr 
        755                 760                 765


Asn Val His Leu Ser His Asp Ala Lys Ser Ala Pro Phe Leu Gly Met 
    770                 775                 780


Ala Pro Ala Val Gln Arg Ser Ala Pro Ala Leu Pro Val Ser Glu Asp 
785                 790                 795                 800


Phe Lys Ser Glu Pro Val Ser Pro Gln Asp Phe Ser Phe Ser Lys Asn 
                805                 810                 815


Gly Leu Leu Ser Arg Leu Leu Arg Gln Asn Gln Asp Ser Tyr Leu Ala 
            820                 825                 830


Asp Asp Ser Asp Arg Ser His Arg Asn Asn Glu Met Ala Leu Leu Glu 
        835                 840                 845


Ser Lys Asn Leu Cys Met Val Pro Lys Lys Arg Lys Leu Tyr Thr Glu 
    850                 855                 860


Pro Leu Glu Asn Pro Phe Lys Lys Met Lys Asn Asn Ile Val Asp Ala 
865                 870                 875                 880


Ala Asn Asn His Ser Ala Pro Glu Val Leu Tyr Gly Ser Leu Leu Asn 
                885                 890                 895


Gln Glu Glu Leu Lys Phe Ser Arg Asn Asp Leu Glu Phe Lys Tyr Pro 
            900                 905                 910


Ala Gly His Gly Ser Ala Ser Glu Ser Glu His Arg Ser Trp Ala Arg 
        915                 920                 925


Glu Ser Lys Ser Phe Asn Val Leu Lys Gln Leu Leu Leu Ser Glu Asn 
    930                 935                 940


Cys Val Arg Asp Leu Ser Pro His Arg Ser Asn Ser Val Ala Asp Ser 
945                 950                 955                 960


Lys Lys Lys Gly His Lys Asn Asn Val Thr Asn Ser Lys Pro Glu Phe 
                965                 970                 975


Ser Ile Ser Ser Leu Asn Gly Leu Met Tyr Ser Ser Thr Gln Pro Ser 
            980                 985                 990


Ser Cys Met Asp Asn Arg Thr Phe Ser Tyr Pro Gly Val Val Lys Thr 
        995                 1000                1005


Pro Val Ser Pro Thr Phe Pro Glu His Leu Gly Cys Ala Gly Ser Arg 
    1010                1015                1020


Pro Glu Ser Gly Leu Leu Asn Gly Cys Ser Met Pro Ser Glu Lys Gly 
1025                1030                1035                1040


Pro Ile Lys Trp Val Ile Thr Asp Ala Glu Lys Asn Glu Tyr Glu Lys 
                1045                1050                1055


Asp Ser Pro Arg Leu Thr Lys Thr Asn Pro Ile Leu Tyr Tyr Met Leu 
            1060                1065                1070


Gln Lys Gly Gly Asn Ser Val Thr Ser Arg Glu Thr Gln Asp Lys Asp 
        1075                1080                1085


Ile Trp Arg Glu Ala Ser Ser Ala Glu Ser Val Ser Gln Val Thr Ala 
    1090                1095                1100


Lys Glu Glu Leu Leu Pro Thr Ala Glu Thr Lys Ala Ser Phe Phe Asn 
1105                1110                1115                1120


Leu Arg Ser Pro Tyr Asn Ser His Met Gly Asn Asn Ala Ser Arg Pro 
                1125                1130                1135


His Ser Ala Asn Gly Glu Val Tyr Gly Leu Leu Gly Ser Val Leu Thr 
            1140                1145                1150


Ile Lys Lys Glu Ser Glu 
        1155


<210>  10243
<211>  7483
<212>  DNA
<213>  Homo sapiens

<400>  10243
agttgtggtt atctcagcag aagacatacc gccctcctcc ttgtattggt cgggacctgg     60

gcattaggga gtcaaggcaa aggagaaaga aaagagattt tacattagta ttctatgaaa    120

gccttacggt ctgcagaaca aattgattac tccggtgtac ctgtgcttgg caccactgct    180

gtgagagaaa gaacactgat atttgcattt aatggggaac aaaagatgaa gaaggaaaag    240

gaatatattc actaaggatt ctatctgctt actgctacag acctatgtgt taaggaattc    300

ttctcctcct ccttgcgtag aagttgatca gcactgtggt cagactgcat ttatcttgtc    360

attgccagaa gaaatcttgg acagaatgta acagtacgtc tctctctgat tgcgatggaa    420

ggtgataaac tgatactcct ttattaaagt tacatcgcac tcaccacaga aaaccattct    480

ttaaagtgaa tagaaaccaa gcccttgtga acacttctat tgaacatgac tcatggagaa    540

gagcttggct ctgatgtgca ccaggattct attgttttaa cttacctaga aggattacta    600

atgcatcagg cagcaggggg atcaggtact gccgttgaca aaaagtctgc tgggcataat    660

gaagaggatc agaactttaa catttctggc agtgcatttc ccacctgtca aagtaatggt    720

ccagttctca atacacatac atatcagggg tctggcatgc tgcacctcaa aaaagccaga    780

ctgttgcagt cttctgagga ctggaatgca gcaaagcgga agaggctgtc tgattctatc    840

atgaatttaa acgtaaagaa ggaagctttg ctagctggca tggttgacag tgtgcctaaa    900

ggcaaacagg atagcacatt actggcctct ttgcttcagt cattcagctc taggctgcag    960

actgttgctc tgtcacaaca aatcaggcag agcctcaagg agcaaggata tgccctcagt   1020

catgattctt taaaagtgga gaaggattta aggtgctatg gtgttgcatc aagtcactta   1080

aaaactttgt tgaagaaaag taaagttaaa gatcaaaagc ctgatacgaa tcttcctgat   1140

gtgactaaaa acctcatcag agataggttt gcagagtctc ctcatcatgt tggacaaagt   1200

ggaacaaagg tcatgagtga accgttgtca tgtgctgcaa gattacaggc tgttgcaagc   1260

atggtggaaa aaagggctag tcctgccacc tcacctaaac ctagtgttgc ttgtagccag   1320

ttagcattac ttctgtcaag cgaagcccat ttgcagcagt attctcgaga acacgcttta   1380

aaaacgcaaa atgcaaatca agcagcaagt gaaagacttg ctgctatggc cagattgcaa   1440

gaaaatggcc agaaggatgt tggcagttac cagctcccaa aaggaatgtc aagccatctt   1500

aatggtcagg caagaacatc atcaagcaaa ctgatggcta gcaaaagtag tgctacagtg   1560

tttcaaaatc caatgggtat cattccttct tcccctaaaa atgcaggtta taagaactca   1620

ctggaaagaa acaatataaa acaagctgct aacaatagtt tgcttttaca tcttcttaaa   1680

agccagacta tacctaagcc aatgaatgga cacagtcaca gtgagagagg aagcattttt   1740

gaggaaagta gtacacctac aactattgat gaatattcag ataacaatcc tagttttaca   1800

gatgacagca gtggtgatga aagttcttat tccaactgtg ttcccataga cttgtcttgc   1860

aaacaccgaa ctgaaaaatc agaatctgac caacctgttt ccctggataa cttcactcaa   1920

tccttgctaa acacttggga tccaaaagtc ccagatgtag atatcaaaga agatcaagat   1980

acctcaaaga attctaagct aaactcacac cagaaagtaa cacttcttca attgctactt   2040

ggccataaga atgaagaaaa tgtagaaaaa aacaccagcc ctcagggagt acacaatgat   2100

gtgagcaagt tcaatacaca aaattatgca aggacttctg tgatagaaag ccccagtaca   2160

aatcggacta ctccagtgag cactccacct ttacttacat caagcaaagc agggtctccc   2220

atcaatctct ctcaacactc tctggtcatc aaatggaatt ccccaccata tgtctgcagt   2280

actcagtctg aaaagctaac aaatactgca tctaaccact caatggacct tacaaaaagc   2340

aaagacccac caggagagaa accagcccaa aatgaaggtg cacagaactc tgcaacgttt   2400

agtgccagta agctgttaca aaatttagca caatgtggaa tgcagtcatc catgtcagtg   2460

gaagagcaga gacccagcaa acagctgtta actggaaaca cagataaacc gataggtatg   2520

attgatagat taaatagccc tttgctctca aataaaacaa atgcagttga agaaaataaa   2580

gcatttagta gtcaaccaac aggtcctgaa ccagggcttt ctggttctga aatagaaaat   2640

ctgcttgaaa gacgtactgt cctccagttg ctcctgggga accccaacaa agggaagagt   2700

gaaaaaaaag agaaaactcc cttaagagat gaaagtactc aggaacactc agagagagct   2760

ttaagtgaac aaatactgat ggtgaaaata aaatctgagc cttgtgatga cttacaaatt   2820

cctaacacaa atgtgcactt gagccatgat gctaagagtg ccccattctt gggtatggct   2880

cctgctgtgc agagaagcgc acctgcctta ccagtgtccg aagactttaa atcggagcct   2940

gtttcacctc aggatttttc tttctccaag aatggtctgc taagtcgatt gctaagacaa   3000

aatcaagata gttacctggc agatgattca gacaggagtc acagaaataa tgaaatggca   3060

cttctagaat caaagaatct ttgcatggtc cctaagaaaa ggaagcttta tactgagcca   3120

ttagaaaatc catttaaaaa gatgaaaaac aacattgttg atgctgcaaa caatcacagt   3180

gccccagaag tactgtatgg gtccttgctt aaccaggaag agctgaaatt tagcagaaat   3240

gatcttgaat ttaaatatcc tgctggtcat ggctcagcca gcgaaagtga acacaggagt   3300

tgggccagag agagcaaaag ctttaatgtt ctgaaacagc tgcttctctc agaaaactgt   3360

gtgcgagatt tgtccccgca cagaagtaac tctgtggctg acagtaaaaa gaaaggacac   3420

aaaaataatg tgaccaacag caaacctgaa tttagcattt cttctttaaa tggactgatg   3480

tacagttcca ctcagcccag cagttgcatg gataacagga cattttcata cccaggtgta   3540

gtaaaaactc ctgtgagtcc tactttccct gagcacttgg gctgtgcagg gtctagacca   3600

gaatctgggc ttttgaatgg gtgttccatg cccagtgaga aaggacccat taagtgggtt   3660

atcactgatg cggagaagaa tgagtatgaa aaagactctc caagattgac caaaaccaac   3720

ccaatactat attacatgct tcaaaaagga ggcaattctg ttaccagtcg agaaacacaa   3780

gacaaggaca tttggaggga ggcttcatct gctgaaagtg tctcacaggt cacagccaaa   3840

gaagagttac ttcctactgc agaaacgaaa gcttctttct ttaatttaag aagcccttac   3900

aatagccata tgggaaataa tgcttctcgc ccacacagcg caaatggaga agtttatgga   3960

cttctgggaa gcgtgctaac gataaagaaa gaatcagaat aaaatgtacc tgccatccag   4020

ttttggatct ttttaaaact aatgagtatg aacttgagat ctgtataaat aagagcatga   4080

tttgaaaaaa agcatggtat aattgaaact tttttcattt tgaaaagtat tggttactgg   4140

tgatgttgaa atatgcatac taatttttgc ttaacattag atgtcatgag gaaactactg   4200

aactagcaat tggttgttta acacttctgt atgcatcaga taacaactgt gagtagccta   4260

tgaatgaaat tcttttataa atattaggca taaattaaaa tgtaaaactc cattcatagt   4320

ggattaatgc attttgctgc ctttattagg gtactttatt ttgcttttca gaagtcagcc   4380

tacataacac atttttaaag tctaaactgt taaacaactc tttaaaggat aattatccaa   4440

taaaaaaaaa cctagtgctg attcacagct tattatccaa ttcaaaaata aattagaaaa   4500

atatatgctt acatttttca cttttgctaa aaagaaaaaa aaaaggtgtt tatttttaac   4560

tcttggaaga ggttttgtgg ttcccaatgt gtctgtccca ccctgatcct tttcaatata   4620

tatttcttta aaccttgtgc tacttagtaa aaattgatta caattgaggg aagtttgata   4680

gatcctttaa aaaaaaggca gatttccatt ttttgtattt taactacttt actaaattaa   4740

tactcctcct tttacagaat tagaaaagtt aacatttatc tttaggtggt ttcctgaaaa   4800

gttgaatatt taagaaattg tttttaacag aagcaaaatg gcttttcttt ggacagtttt   4860

caccatctct tgtaaaagtt aattctcacc attcctgtgg tacctgcgag tgttatgacc   4920

aggattcctt aaacctgaac tcagaccact tgcattagaa ccatctggag cacttgtttt   4980

aaaatgcaga ttcataggca gcatctcaga tctacagaac aagaatctct gctaagtgga   5040

cctggaatct tccatctgca tcttaacatg ctctctaggt gtttcttgtg tttgagaacc   5100

atgacttatg actttcctca gaacatgaga ctgtaaaaca aaaacaaaaa actatgtgat   5160

gcctctattt tccccaatac agtcacacat cagctcaaaa tttgcaatat tgtagttcat   5220

atattaccgt tatgtctttg gaaatcgggt tcagaacact ttttatgaca aaaattgggt   5280

ggaggggata actttcatat ctggctcaac atctcaggaa aatctgtgat tatttgtgtg   5340

ttctaatgag taacatctac ttagttagcc ttagggatgg aaaaacaggg ccacttacca   5400

aactcaggtg attccaggat ggtttggaaa cttctcctga atgcatcctt aacctttatt   5460

aaaaccattg tcctaagaac aatgccaaca aagcttacaa catttagttt aaacccaaga   5520

agggcactaa actcagattg actaaataaa aagtacaaag ggcacatata cgtgacagaa   5580

ttgtacacaa tcactccatt ggatctttta ctttaaagta gtgatgaaaa gtacatgttg   5640

atactgtctt agaagaaatt aatatattag tgaagccaca tggggtttca gttgcgaaac   5700

aggtctgttt ttatgttcag tttgtacaat ccacaattca ttcaccagat attttgttct   5760

taattgtgaa ccaggttagc aaatgaccta tcaaaaatta ttctataatc actactagtt   5820

aggatattga tttaaaattg ttctacttga agtggtttct aagattttta tattaaaaat   5880

aggtgtgatt tcctaatatg atctaaaacc ctaaatggtt atttttcctc agaatgattt   5940

gtaaatagct actggaaata ttatacagta ataggagtgg gtattatgca acatcatgga   6000

gaagtgaagg cataggctta ttctgacata aaattccact ggccagttga atatattcta   6060

ttccatgtcc atactatgac aatcttattg tcaacactat ataaataagc ttttaaacaa   6120

gtcatttttc ttgatcgttg tggaaggttt ggagccttag aggtatgtca gaaaaaatat   6180

gttggtattc tcccttgggt agggggaaat gaccttttta caagagagtg aaatttaggt   6240

cagggaaaag accaagggcc agcattgcta cttttgtgtg tgtgtgtgtg ggttttgttt   6300

tgtttttttg gttggctggt tgttttcgtt gttgttaaca aaggaatgag aatatgtaat   6360

acttaaataa acatgaccac gaagaatgct gttctgattt actagagaat gttcccaatt   6420

tgaatttagg gtgattttaa agaacagtga gaaagggcat acatccacag attcactttg   6480

tttatgcata tgtagataca aggatgcaca tatacacatt ttcaaggact attttagata   6540

tctagacaat ttcttctaat aaagtcattt gtgaaagggt actacagctt attgacatca   6600

gtaaggtagc attcattacc tgtttattct ctgctgcatc ttacagaaga gtaaactggt   6660

gagagtatat attttatata tatatatata tatatatata taatatgtat atatatatat   6720

attgacttgt tacatgaaga tgttaaaatc ggtttttaaa ggtgatgtaa atagtgattt   6780

ccttaatgaa aaatacatat tttgtattgt tctaatgcaa cagaaaagcc ttttaatctc   6840

tttggttcct gtatattcca tgtataagtg taaatataat cagacaggtt taaaagttgt   6900

gcatgtatgt atacagttgc aagtctggac aaatgtatag aataaacctt ttatttaagt   6960

tgtgattacc tgctgcatga aaagtgcatg ggggaccctg tgcatctgtg catttggcaa   7020

aatgtcttaa caaatcagat cagatgttca tcctaacatg acagtattcc atttctggac   7080

atgacgtctg tggtttaagc tttgtgaaag aatgtgcttt gattcgaagg gtcttaaaga   7140

atttttttaa tcgtcaacca cttttaaaca taaagaattc acacaactac tttcatgaat   7200

tttttaatcc cattgcaaac attattccaa gagtatccca gtattagcaa tactggaata   7260

taggcacatt accattcata gtaagaattc tggtgtttac acaaccaaat ttgatgcgat   7320

ctgctcagta atataatttg ccatttttat tagaaattta atttcttcat gtgatgtcat   7380

gaaactgtac atactgcagt gtgaattttt ttgttttgtt ttttaatctt ttagtgttta   7440

cttcctgcag tgaatttgaa taaatgagaa aaaatgcatt gtc                     7483


<210>  10244
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  10244

Met Lys Ala Leu Arg Ser Ala Glu Gln Ile Asp Tyr Ser Gly Val Pro 
1               5                   10                  15


Val Leu Gly Thr Thr Ala Val Arg Glu Arg Thr Leu Ile Phe Ala Phe 
            20                  25                  30


Asn Gly Glu Gln Lys Met Lys Lys Glu Lys Glu Tyr Ile His 
        35                  40                  45


<210>  10245
<211>  7669
<212>  DNA
<213>  Homo sapiens

<400>  10245
ccgcccgcca cccgcgcgcg cccgtccgcc cgtggcctcg cgtccgccgc tgcgccgtga     60

gcgccgctgg tcggagggaa gagctcgccg gggcgccggg ccaggacggg gcggcaggcg    120

ccttcgcgga ccgagcctga cggagccgga ggctgggagc cgcggcggcc tggggaagtg    180

tttggattgt gagctatttc agaactgttc tcaggactca ttattttaac atttgggaga    240

aacacagcca gaagatgcac acttgactga aggaggacag ggaatctgaa gactccggat    300

gacatcagag ctacttttca acagccttct caattttctt tctcagaaag cagaggctca    360

gagcttggag acagacgaac actgatattt gcatttaatg gggaacaaaa gatgaagaag    420

gaaaaggaat atattcacta aggattctat ctgcttactg ctacagacct atgtgttaag    480

gaattcttct cctcctcctt gcgtagaagt tgatcagcac tgtggtcaga ctgcatttat    540

cttgtcattg ccagaagaaa tcttggacag aatgtaacag tacgtctctc tctgattgcg    600

atggaaggtg ataaactgat actcctttat taaagttaca tcgcactcac cacagaaaac    660

cattctttaa agtgaataga aaccaagccc ttgtgaacac ttctattgaa catgactcat    720

ggagaagagc ttggctctga tgtgcaccag gattctattg ttttaactta cctagaagga    780

ttactaatgc atcaggcagc agggggatca ggtactgccg ttgacaaaaa gtctgctggg    840

cataatgaag aggatcagaa ctttaacatt tctggcagtg catttcccac ctgtcaaagt    900

aatggtccag ttctcaatac acatacatat caggggtctg gcatgctgca cctcaaaaaa    960

gccagactgt tgcagtcttc tgaggactgg aatgcagcaa agcggaagag gctgtctgat   1020

tctatcatga atttaaacgt aaagaaggaa gctttgctag ctggcatggt tgacagtgtg   1080

cctaaaggca aacaggatag cacattactg gcctctttgc ttcagtcatt cagctctagg   1140

ctgcagactg ttgctctgtc acaacaaatc aggcagagcc tcaaggagca aggatatgcc   1200

ctcagtcatg attctttaaa agtggagaag gatttaaggt gctatggtgt tgcatcaagt   1260

cacttaaaaa ctttgttgaa gaaaagtaaa gttaaagatc aaaagcctga tacgaatctt   1320

cctgatgtga ctaaaaacct catcagagat aggtttgcag agtctcctca tcatgttgga   1380

caaagtggaa caaaggtcat gagtgaaccg ttgtcatgtg ctgcaagatt acaggctgtt   1440

gcaagcatgg tggaaaaaag ggctagtcct gccacctcac ctaaacctag tgttgcttgt   1500

agccagttag cattacttct gtcaagcgaa gcccatttgc agcagtattc tcgagaacac   1560

gctttaaaaa cgcaaaatgc aaatcaagca gcaagtgaaa gacttgctgc tatggccaga   1620

ttgcaagaaa atggccagaa ggatgttggc agttaccagc tcccaaaagg aatgtcaagc   1680

catcttaatg gtcaggcaag aacatcatca agcaaactga tggctagcaa aagtagtgct   1740

acagtgtttc aaaatccaat gggtatcatt ccttcttccc ctaaaaatgc aggttataag   1800

aactcactgg aaagaaacaa tataaaacaa gctgctaaca atagtttgct tttacatctt   1860

cttaaaagcc agactatacc taagccaatg aatggacaca gtcacagtga gagaggaagc   1920

atttttgagg aaagtagtac acctacaact attgatgaat attcagataa caatcctagt   1980

tttacagatg acagcagtgg tgatgaaagt tcttattcca actgtgttcc catagacttg   2040

tcttgcaaac accgaactga aaaatcagaa tctgaccaac ctgtttccct ggataacttc   2100

actcaatcct tgctaaacac ttgggatcca aaagtcccag atgtagatat caaagaagat   2160

caagatacct caaagaattc taagctaaac tcacaccaga aagtaacact tcttcaattg   2220

ctacttggcc ataagaatga agaaaatgta gaaaaaaaca ccagccctca gggagtacac   2280

aatgatgtga gcaagttcaa tacacaaaat tatgcaagga cttctgtgat agaaagcccc   2340

agtacaaatc ggactactcc agtgagcact ccacctttac ttacatcaag caaagcaggg   2400

tctcccatca atctctctca acactctctg gtcatcaaat ggaattcccc accatatgtc   2460

tgcagtactc agtctgaaaa gctaacaaat actgcatcta accactcaat ggaccttaca   2520

aaaagcaaag acccaccagg agagaaacca gcccaaaatg aaggtgcaca gaactctgca   2580

acgtttagtg ccagtaagct gttacaaaat ttagcacaat gtggaatgca gtcatccatg   2640

tcagtggaag agcagagacc cagcaaacag ctgttaactg gaaacacaga taaaccgata   2700

ggtatgattg atagattaaa tagccctttg ctctcaaata aaacaaatgc agttgaagaa   2760

aataaagcat ttagtagtca accaacaggt cctgaaccag ggctttctgg ttctgaaata   2820

gaaaatctgc ttgaaagacg tactgtcctc cagttgctcc tggggaaccc caacaaaggg   2880

aagagtgaaa aaaaagagaa aactccctta agagatgaaa gtactcagga acactcagag   2940

agagctttaa gtgaacaaat actgatggtg aaaataaaat ctgagccttg tgatgactta   3000

caaattccta acacaaatgt gcacttgagc catgatgcta agagtgcccc attcttgggt   3060

atggctcctg ctgtgcagag aagcgcacct gccttaccag tgtccgaaga ctttaaatcg   3120

gagcctgttt cacctcagga tttttctttc tccaagaatg gtctgctaag tcgattgcta   3180

agacaaaatc aagatagtta cctggcagat gattcagaca ggagtcacag aaataatgaa   3240

atggcacttc tagaatcaaa gaatctttgc atggtcccta agaaaaggaa gctttatact   3300

gagccattag aaaatccatt taaaaagatg aaaaacaaca ttgttgatgc tgcaaacaat   3360

cacagtgccc cagaagtact gtatgggtcc ttgcttaacc aggaagagct gaaatttagc   3420

agaaatgatc ttgaatttaa atatcctgct ggtcatggct cagccagcga aagtgaacac   3480

aggagttggg ccagagagag caaaagcttt aatgttctga aacagctgct tctctcagaa   3540

aactgtgtgc gagatttgtc cccgcacaga agtaactctg tggctgacag taaaaagaaa   3600

ggacacaaaa ataatgtgac caacagcaaa cctgaattta gcatttcttc tttaaatgga   3660

ctgatgtaca gttccactca gcccagcagt tgcatggata acaggacatt ttcataccca   3720

ggtgtagtaa aaactcctgt gagtcctact ttccctgagc acttgggctg tgcagggtct   3780

agaccagaat ctgggctttt gaatgggtgt tccatgccca gtgagaaagg acccattaag   3840

tgggttatca ctgatgcgga gaagaatgag tatgaaaaag actctccaag attgaccaaa   3900

accaacccaa tactatatta catgcttcaa aaaggaggca attctgttac cagtcgagaa   3960

acacaagaca aggacatttg gagggaggct tcatctgctg aaagtgtctc acaggtcaca   4020

gccaaagaag agttacttcc tactgcagaa acgaaagctt ctttctttaa tttaagaagc   4080

ccttacaata gccatatggg aaataatgct tctcgcccac acagcgcaaa tggagaagtt   4140

tatggacttc tgggaagcgt gctaacgata aagaaagaat cagaataaaa tgtacctgcc   4200

atccagtttt ggatcttttt aaaactaatg agtatgaact tgagatctgt ataaataaga   4260

gcatgatttg aaaaaaagca tggtataatt gaaacttttt tcattttgaa aagtattggt   4320

tactggtgat gttgaaatat gcatactaat ttttgcttaa cattagatgt catgaggaaa   4380

ctactgaact agcaattggt tgtttaacac ttctgtatgc atcagataac aactgtgagt   4440

agcctatgaa tgaaattctt ttataaatat taggcataaa ttaaaatgta aaactccatt   4500

catagtggat taatgcattt tgctgccttt attagggtac tttattttgc ttttcagaag   4560

tcagcctaca taacacattt ttaaagtcta aactgttaaa caactcttta aaggataatt   4620

atccaataaa aaaaaaccta gtgctgattc acagcttatt atccaattca aaaataaatt   4680

agaaaaatat atgcttacat ttttcacttt tgctaaaaag aaaaaaaaaa ggtgtttatt   4740

tttaactctt ggaagaggtt ttgtggttcc caatgtgtct gtcccaccct gatccttttc   4800

aatatatatt tctttaaacc ttgtgctact tagtaaaaat tgattacaat tgagggaagt   4860

ttgatagatc ctttaaaaaa aaggcagatt tccatttttt gtattttaac tactttacta   4920

aattaatact cctcctttta cagaattaga aaagttaaca tttatcttta ggtggtttcc   4980

tgaaaagttg aatatttaag aaattgtttt taacagaagc aaaatggctt ttctttggac   5040

agttttcacc atctcttgta aaagttaatt ctcaccattc ctgtggtacc tgcgagtgtt   5100

atgaccagga ttccttaaac ctgaactcag accacttgca ttagaaccat ctggagcact   5160

tgttttaaaa tgcagattca taggcagcat ctcagatcta cagaacaaga atctctgcta   5220

agtggacctg gaatcttcca tctgcatctt aacatgctct ctaggtgttt cttgtgtttg   5280

agaaccatga cttatgactt tcctcagaac atgagactgt aaaacaaaaa caaaaaacta   5340

tgtgatgcct ctattttccc caatacagtc acacatcagc tcaaaatttg caatattgta   5400

gttcatatat taccgttatg tctttggaaa tcgggttcag aacacttttt atgacaaaaa   5460

ttgggtggag gggataactt tcatatctgg ctcaacatct caggaaaatc tgtgattatt   5520

tgtgtgttct aatgagtaac atctacttag ttagccttag ggatggaaaa acagggccac   5580

ttaccaaact caggtgattc caggatggtt tggaaacttc tcctgaatgc atccttaacc   5640

tttattaaaa ccattgtcct aagaacaatg ccaacaaagc ttacaacatt tagtttaaac   5700

ccaagaaggg cactaaactc agattgacta aataaaaagt acaaagggca catatacgtg   5760

acagaattgt acacaatcac tccattggat cttttacttt aaagtagtga tgaaaagtac   5820

atgttgatac tgtcttagaa gaaattaata tattagtgaa gccacatggg gtttcagttg   5880

cgaaacaggt ctgtttttat gttcagtttg tacaatccac aattcattca ccagatattt   5940

tgttcttaat tgtgaaccag gttagcaaat gacctatcaa aaattattct ataatcacta   6000

ctagttagga tattgattta aaattgttct acttgaagtg gtttctaaga tttttatatt   6060

aaaaataggt gtgatttcct aatatgatct aaaaccctaa atggttattt ttcctcagaa   6120

tgatttgtaa atagctactg gaaatattat acagtaatag gagtgggtat tatgcaacat   6180

catggagaag tgaaggcata ggcttattct gacataaaat tccactggcc agttgaatat   6240

attctattcc atgtccatac tatgacaatc ttattgtcaa cactatataa ataagctttt   6300

aaacaagtca tttttcttga tcgttgtgga aggtttggag ccttagaggt atgtcagaaa   6360

aaatatgttg gtattctccc ttgggtaggg ggaaatgacc tttttacaag agagtgaaat   6420

ttaggtcagg gaaaagacca agggccagca ttgctacttt tgtgtgtgtg tgtgtgggtt   6480

ttgttttgtt tttttggttg gctggttgtt ttcgttgttg ttaacaaagg aatgagaata   6540

tgtaatactt aaataaacat gaccacgaag aatgctgttc tgatttacta gagaatgttc   6600

ccaatttgaa tttagggtga ttttaaagaa cagtgagaaa gggcatacat ccacagattc   6660

actttgttta tgcatatgta gatacaagga tgcacatata cacattttca aggactattt   6720

tagatatcta gacaatttct tctaataaag tcatttgtga aagggtacta cagcttattg   6780

acatcagtaa ggtagcattc attacctgtt tattctctgc tgcatcttac agaagagtaa   6840

actggtgaga gtatatattt tatatatata tatatatata tatatataat atgtatatat   6900

atatatattg acttgttaca tgaagatgtt aaaatcggtt tttaaaggtg atgtaaatag   6960

tgatttcctt aatgaaaaat acatattttg tattgttcta atgcaacaga aaagcctttt   7020

aatctctttg gttcctgtat attccatgta taagtgtaaa tataatcaga caggtttaaa   7080

agttgtgcat gtatgtatac agttgcaagt ctggacaaat gtatagaata aaccttttat   7140

ttaagttgtg attacctgct gcatgaaaag tgcatggggg accctgtgca tctgtgcatt   7200

tggcaaaatg tcttaacaaa tcagatcaga tgttcatcct aacatgacag tattccattt   7260

ctggacatga cgtctgtggt ttaagctttg tgaaagaatg tgctttgatt cgaagggtct   7320

taaagaattt ttttaatcgt caaccacttt taaacataaa gaattcacac aactactttc   7380

atgaattttt taatcccatt gcaaacatta ttccaagagt atcccagtat tagcaatact   7440

ggaatatagg cacattacca ttcatagtaa gaattctggt gtttacacaa ccaaatttga   7500

tgcgatctgc tcagtaatat aatttgccat ttttattaga aatttaattt cttcatgtga   7560

tgtcatgaaa ctgtacatac tgcagtgtga atttttttgt tttgtttttt aatcttttag   7620

tgtttacttc ctgcagtgaa tttgaataaa tgagaaaaaa tgcattgtc               7669


<210>  10246
<211>  1158
<212>  PRT
<213>  Homo sapiens

<400>  10246

Met Thr His Gly Glu Glu Leu Gly Ser Asp Val His Gln Asp Ser Ile 
1               5                   10                  15


Val Leu Thr Tyr Leu Glu Gly Leu Leu Met His Gln Ala Ala Gly Gly 
            20                  25                  30


Ser Gly Thr Ala Val Asp Lys Lys Ser Ala Gly His Asn Glu Glu Asp 
        35                  40                  45


Gln Asn Phe Asn Ile Ser Gly Ser Ala Phe Pro Thr Cys Gln Ser Asn 
    50                  55                  60


Gly Pro Val Leu Asn Thr His Thr Tyr Gln Gly Ser Gly Met Leu His 
65                  70                  75                  80


Leu Lys Lys Ala Arg Leu Leu Gln Ser Ser Glu Asp Trp Asn Ala Ala 
                85                  90                  95


Lys Arg Lys Arg Leu Ser Asp Ser Ile Met Asn Leu Asn Val Lys Lys 
            100                 105                 110


Glu Ala Leu Leu Ala Gly Met Val Asp Ser Val Pro Lys Gly Lys Gln 
        115                 120                 125


Asp Ser Thr Leu Leu Ala Ser Leu Leu Gln Ser Phe Ser Ser Arg Leu 
    130                 135                 140


Gln Thr Val Ala Leu Ser Gln Gln Ile Arg Gln Ser Leu Lys Glu Gln 
145                 150                 155                 160


Gly Tyr Ala Leu Ser His Asp Ser Leu Lys Val Glu Lys Asp Leu Arg 
                165                 170                 175


Cys Tyr Gly Val Ala Ser Ser His Leu Lys Thr Leu Leu Lys Lys Ser 
            180                 185                 190


Lys Val Lys Asp Gln Lys Pro Asp Thr Asn Leu Pro Asp Val Thr Lys 
        195                 200                 205


Asn Leu Ile Arg Asp Arg Phe Ala Glu Ser Pro His His Val Gly Gln 
    210                 215                 220


Ser Gly Thr Lys Val Met Ser Glu Pro Leu Ser Cys Ala Ala Arg Leu 
225                 230                 235                 240


Gln Ala Val Ala Ser Met Val Glu Lys Arg Ala Ser Pro Ala Thr Ser 
                245                 250                 255


Pro Lys Pro Ser Val Ala Cys Ser Gln Leu Ala Leu Leu Leu Ser Ser 
            260                 265                 270


Glu Ala His Leu Gln Gln Tyr Ser Arg Glu His Ala Leu Lys Thr Gln 
        275                 280                 285


Asn Ala Asn Gln Ala Ala Ser Glu Arg Leu Ala Ala Met Ala Arg Leu 
    290                 295                 300


Gln Glu Asn Gly Gln Lys Asp Val Gly Ser Tyr Gln Leu Pro Lys Gly 
305                 310                 315                 320


Met Ser Ser His Leu Asn Gly Gln Ala Arg Thr Ser Ser Ser Lys Leu 
                325                 330                 335


Met Ala Ser Lys Ser Ser Ala Thr Val Phe Gln Asn Pro Met Gly Ile 
            340                 345                 350


Ile Pro Ser Ser Pro Lys Asn Ala Gly Tyr Lys Asn Ser Leu Glu Arg 
        355                 360                 365


Asn Asn Ile Lys Gln Ala Ala Asn Asn Ser Leu Leu Leu His Leu Leu 
    370                 375                 380


Lys Ser Gln Thr Ile Pro Lys Pro Met Asn Gly His Ser His Ser Glu 
385                 390                 395                 400


Arg Gly Ser Ile Phe Glu Glu Ser Ser Thr Pro Thr Thr Ile Asp Glu 
                405                 410                 415


Tyr Ser Asp Asn Asn Pro Ser Phe Thr Asp Asp Ser Ser Gly Asp Glu 
            420                 425                 430


Ser Ser Tyr Ser Asn Cys Val Pro Ile Asp Leu Ser Cys Lys His Arg 
        435                 440                 445


Thr Glu Lys Ser Glu Ser Asp Gln Pro Val Ser Leu Asp Asn Phe Thr 
    450                 455                 460


Gln Ser Leu Leu Asn Thr Trp Asp Pro Lys Val Pro Asp Val Asp Ile 
465                 470                 475                 480


Lys Glu Asp Gln Asp Thr Ser Lys Asn Ser Lys Leu Asn Ser His Gln 
                485                 490                 495


Lys Val Thr Leu Leu Gln Leu Leu Leu Gly His Lys Asn Glu Glu Asn 
            500                 505                 510


Val Glu Lys Asn Thr Ser Pro Gln Gly Val His Asn Asp Val Ser Lys 
        515                 520                 525


Phe Asn Thr Gln Asn Tyr Ala Arg Thr Ser Val Ile Glu Ser Pro Ser 
    530                 535                 540


Thr Asn Arg Thr Thr Pro Val Ser Thr Pro Pro Leu Leu Thr Ser Ser 
545                 550                 555                 560


Lys Ala Gly Ser Pro Ile Asn Leu Ser Gln His Ser Leu Val Ile Lys 
                565                 570                 575


Trp Asn Ser Pro Pro Tyr Val Cys Ser Thr Gln Ser Glu Lys Leu Thr 
            580                 585                 590


Asn Thr Ala Ser Asn His Ser Met Asp Leu Thr Lys Ser Lys Asp Pro 
        595                 600                 605


Pro Gly Glu Lys Pro Ala Gln Asn Glu Gly Ala Gln Asn Ser Ala Thr 
    610                 615                 620


Phe Ser Ala Ser Lys Leu Leu Gln Asn Leu Ala Gln Cys Gly Met Gln 
625                 630                 635                 640


Ser Ser Met Ser Val Glu Glu Gln Arg Pro Ser Lys Gln Leu Leu Thr 
                645                 650                 655


Gly Asn Thr Asp Lys Pro Ile Gly Met Ile Asp Arg Leu Asn Ser Pro 
            660                 665                 670


Leu Leu Ser Asn Lys Thr Asn Ala Val Glu Glu Asn Lys Ala Phe Ser 
        675                 680                 685


Ser Gln Pro Thr Gly Pro Glu Pro Gly Leu Ser Gly Ser Glu Ile Glu 
    690                 695                 700


Asn Leu Leu Glu Arg Arg Thr Val Leu Gln Leu Leu Leu Gly Asn Pro 
705                 710                 715                 720


Asn Lys Gly Lys Ser Glu Lys Lys Glu Lys Thr Pro Leu Arg Asp Glu 
                725                 730                 735


Ser Thr Gln Glu His Ser Glu Arg Ala Leu Ser Glu Gln Ile Leu Met 
            740                 745                 750


Val Lys Ile Lys Ser Glu Pro Cys Asp Asp Leu Gln Ile Pro Asn Thr 
        755                 760                 765


Asn Val His Leu Ser His Asp Ala Lys Ser Ala Pro Phe Leu Gly Met 
    770                 775                 780


Ala Pro Ala Val Gln Arg Ser Ala Pro Ala Leu Pro Val Ser Glu Asp 
785                 790                 795                 800


Phe Lys Ser Glu Pro Val Ser Pro Gln Asp Phe Ser Phe Ser Lys Asn 
                805                 810                 815


Gly Leu Leu Ser Arg Leu Leu Arg Gln Asn Gln Asp Ser Tyr Leu Ala 
            820                 825                 830


Asp Asp Ser Asp Arg Ser His Arg Asn Asn Glu Met Ala Leu Leu Glu 
        835                 840                 845


Ser Lys Asn Leu Cys Met Val Pro Lys Lys Arg Lys Leu Tyr Thr Glu 
    850                 855                 860


Pro Leu Glu Asn Pro Phe Lys Lys Met Lys Asn Asn Ile Val Asp Ala 
865                 870                 875                 880


Ala Asn Asn His Ser Ala Pro Glu Val Leu Tyr Gly Ser Leu Leu Asn 
                885                 890                 895


Gln Glu Glu Leu Lys Phe Ser Arg Asn Asp Leu Glu Phe Lys Tyr Pro 
            900                 905                 910


Ala Gly His Gly Ser Ala Ser Glu Ser Glu His Arg Ser Trp Ala Arg 
        915                 920                 925


Glu Ser Lys Ser Phe Asn Val Leu Lys Gln Leu Leu Leu Ser Glu Asn 
    930                 935                 940


Cys Val Arg Asp Leu Ser Pro His Arg Ser Asn Ser Val Ala Asp Ser 
945                 950                 955                 960


Lys Lys Lys Gly His Lys Asn Asn Val Thr Asn Ser Lys Pro Glu Phe 
                965                 970                 975


Ser Ile Ser Ser Leu Asn Gly Leu Met Tyr Ser Ser Thr Gln Pro Ser 
            980                 985                 990


Ser Cys Met Asp Asn Arg Thr Phe Ser Tyr Pro Gly Val Val Lys Thr 
        995                 1000                1005


Pro Val Ser Pro Thr Phe Pro Glu His Leu Gly Cys Ala Gly Ser Arg 
    1010                1015                1020


Pro Glu Ser Gly Leu Leu Asn Gly Cys Ser Met Pro Ser Glu Lys Gly 
1025                1030                1035                1040


Pro Ile Lys Trp Val Ile Thr Asp Ala Glu Lys Asn Glu Tyr Glu Lys 
                1045                1050                1055


Asp Ser Pro Arg Leu Thr Lys Thr Asn Pro Ile Leu Tyr Tyr Met Leu 
            1060                1065                1070


Gln Lys Gly Gly Asn Ser Val Thr Ser Arg Glu Thr Gln Asp Lys Asp 
        1075                1080                1085


Ile Trp Arg Glu Ala Ser Ser Ala Glu Ser Val Ser Gln Val Thr Ala 
    1090                1095                1100


Lys Glu Glu Leu Leu Pro Thr Ala Glu Thr Lys Ala Ser Phe Phe Asn 
1105                1110                1115                1120


Leu Arg Ser Pro Tyr Asn Ser His Met Gly Asn Asn Ala Ser Arg Pro 
                1125                1130                1135


His Ser Ala Asn Gly Glu Val Tyr Gly Leu Leu Gly Ser Val Leu Thr 
            1140                1145                1150


Ile Lys Lys Glu Ser Glu 
        1155


<210>  10247
<211>  7562
<212>  DNA
<213>  Homo sapiens

<400>  10247
cgacccggcc ccacgcccgc ccgccacccg cgcgcgcccg tccgcccgtg gcctcgcgtc     60

cgccgctgcg ccgtgagcgc cgctggtcgg agggaagagc tcgccggggc gccgggccag    120

gacggggcgg caggcgcctt cgcggaccga gcctgacgga gccggaggct gggagccgcg    180

gcggcctggg gaagtgtttg gattgtgagc tatttcagaa ctgttctcag gactcattat    240

tttaacattt gggagaaaca cagccagaag aacactgata tttgcattta atggggaaca    300

aaagatgaag aaggaaaagg aatatattca ctaaggattc tatctgctta ctgctacaga    360

cctatgtgtt aaggaattct tctcctcctc cttgcgtaga agttgatcag cactgtggtc    420

agactgcatt tatcttgtca ttgccagaag aaatcttgga cagaatgtaa cagtacgtct    480

ctctctgatt gcgatggaag gtgataaact gatactcctt tattaaagtt acatcgcact    540

caccacagaa aaccattctt taaagtgaat agaaaccaag cccttgtgaa cacttctatt    600

gaacatgact catggagaag agcttggctc tgatgtgcac caggattcta ttgttttaac    660

ttacctagaa ggattactaa tgcatcaggc agcaggggga tcaggtactg ccgttgacaa    720

aaagtctgct gggcataatg aagaggatca gaactttaac atttctggca gtgcatttcc    780

cacctgtcaa agtaatggtc cagttctcaa tacacataca tatcaggggt ctggcatgct    840

gcacctcaaa aaagccagac tgttgcagtc ttctgaggac tggaatgcag caaagcggaa    900

gaggctgtct gattctatca tgaatttaaa cgtaaagaag gaagctttgc tagctggcat    960

ggttgacagt gtgcctaaag gcaaacagga tagcacatta ctggcctctt tgcttcagtc   1020

attcagctct aggctgcaga ctgttgctct gtcacaacaa atcaggcaga gcctcaagga   1080

gcaaggatat gccctcagtc atgattcttt aaaagtggag aaggatttaa ggtgctatgg   1140

tgttgcatca agtcacttaa aaactttgtt gaagaaaagt aaagttaaag atcaaaagcc   1200

tgatacgaat cttcctgatg tgactaaaaa cctcatcaga gataggtttg cagagtctcc   1260

tcatcatgtt ggacaaagtg gaacaaaggt catgagtgaa ccgttgtcat gtgctgcaag   1320

attacaggct gttgcaagca tggtggaaaa aagggctagt cctgccacct cacctaaacc   1380

tagtgttgct tgtagccagt tagcattact tctgtcaagc gaagcccatt tgcagcagta   1440

ttctcgagaa cacgctttaa aaacgcaaaa tgcaaatcaa gcagcaagtg aaagacttgc   1500

tgctatggcc agattgcaag aaaatggcca gaaggatgtt ggcagttacc agctcccaaa   1560

aggaatgtca agccatctta atggtcaggc aagaacatca tcaagcaaac tgatggctag   1620

caaaagtagt gctacagtgt ttcaaaatcc aatgggtatc attccttctt cccctaaaaa   1680

tgcaggttat aagaactcac tggaaagaaa caatataaaa caagctgcta acaatagttt   1740

gcttttacat cttcttaaaa gccagactat acctaagcca atgaatggac acagtcacag   1800

tgagagagga agcatttttg aggaaagtag tacacctaca actattgatg aatattcaga   1860

taacaatcct agttttacag atgacagcag tggtgatgaa agttcttatt ccaactgtgt   1920

tcccatagac ttgtcttgca aacaccgaac tgaaaaatca gaatctgacc aacctgtttc   1980

cctggataac ttcactcaat ccttgctaaa cacttgggat ccaaaagtcc cagatgtaga   2040

tatcaaagaa gatcaagata cctcaaagaa ttctaagcta aactcacacc agaaagtaac   2100

acttcttcaa ttgctacttg gccataagaa tgaagaaaat gtagaaaaaa acaccagccc   2160

tcagggagta cacaatgatg tgagcaagtt caatacacaa aattatgcaa ggacttctgt   2220

gatagaaagc cccagtacaa atcggactac tccagtgagc actccacctt tacttacatc   2280

aagcaaagca gggtctccca tcaatctctc tcaacactct ctggtcatca aatggaattc   2340

cccaccatat gtctgcagta ctcagtctga aaagctaaca aatactgcat ctaaccactc   2400

aatggacctt acaaaaagca aagacccacc aggagagaaa ccagcccaaa atgaaggtgc   2460

acagaactct gcaacgttta gtgccagtaa gctgttacaa aatttagcac aatgtggaat   2520

gcagtcatcc atgtcagtgg aagagcagag acccagcaaa cagctgttaa ctggaaacac   2580

agataaaccg ataggtatga ttgatagatt aaatagccct ttgctctcaa ataaaacaaa   2640

tgcagttgaa gaaaataaag catttagtag tcaaccaaca ggtcctgaac cagggctttc   2700

tggttctgaa atagaaaatc tgcttgaaag acgtactgtc ctccagttgc tcctggggaa   2760

ccccaacaaa gggaagagtg aaaaaaaaga gaaaactccc ttaagagatg aaagtactca   2820

ggaacactca gagagagctt taagtgaaca aatactgatg gtgaaaataa aatctgagcc   2880

ttgtgatgac ttacaaattc ctaacacaaa tgtgcacttg agccatgatg ctaagagtgc   2940

cccattcttg ggtatggctc ctgctgtgca gagaagcgca cctgccttac cagtgtccga   3000

agactttaaa tcggagcctg tttcacctca ggatttttct ttctccaaga atggtctgct   3060

aagtcgattg ctaagacaaa atcaagatag ttacctggca gatgattcag acaggagtca   3120

cagaaataat gaaatggcac ttctagaatc aaagaatctt tgcatggtcc ctaagaaaag   3180

gaagctttat actgagccat tagaaaatcc atttaaaaag atgaaaaaca acattgttga   3240

tgctgcaaac aatcacagtg ccccagaagt actgtatggg tccttgctta accaggaaga   3300

gctgaaattt agcagaaatg atcttgaatt taaatatcct gctggtcatg gctcagccag   3360

cgaaagtgaa cacaggagtt gggccagaga gagcaaaagc tttaatgttc tgaaacagct   3420

gcttctctca gaaaactgtg tgcgagattt gtccccgcac agaagtaact ctgtggctga   3480

cagtaaaaag aaaggacaca aaaataatgt gaccaacagc aaacctgaat ttagcatttc   3540

ttctttaaat ggactgatgt acagttccac tcagcccagc agttgcatgg ataacaggac   3600

attttcatac ccaggtgtag taaaaactcc tgtgagtcct actttccctg agcacttggg   3660

ctgtgcaggg tctagaccag aatctgggct tttgaatggg tgttccatgc ccagtgagaa   3720

aggacccatt aagtgggtta tcactgatgc ggagaagaat gagtatgaaa aagactctcc   3780

aagattgacc aaaaccaacc caatactata ttacatgctt caaaaaggag gcaattctgt   3840

taccagtcga gaaacacaag acaaggacat ttggagggag gcttcatctg ctgaaagtgt   3900

ctcacaggtc acagccaaag aagagttact tcctactgca gaaacgaaag cttctttctt   3960

taatttaaga agcccttaca atagccatat gggaaataat gcttctcgcc cacacagcgc   4020

aaatggagaa gtttatggac ttctgggaag cgtgctaacg ataaagaaag aatcagaata   4080

aaatgtacct gccatccagt tttggatctt tttaaaacta atgagtatga acttgagatc   4140

tgtataaata agagcatgat ttgaaaaaaa gcatggtata attgaaactt ttttcatttt   4200

gaaaagtatt ggttactggt gatgttgaaa tatgcatact aatttttgct taacattaga   4260

tgtcatgagg aaactactga actagcaatt ggttgtttaa cacttctgta tgcatcagat   4320

aacaactgtg agtagcctat gaatgaaatt cttttataaa tattaggcat aaattaaaat   4380

gtaaaactcc attcatagtg gattaatgca ttttgctgcc tttattaggg tactttattt   4440

tgcttttcag aagtcagcct acataacaca tttttaaagt ctaaactgtt aaacaactct   4500

ttaaaggata attatccaat aaaaaaaaac ctagtgctga ttcacagctt attatccaat   4560

tcaaaaataa attagaaaaa tatatgctta catttttcac ttttgctaaa aagaaaaaaa   4620

aaaggtgttt atttttaact cttggaagag gttttgtggt tcccaatgtg tctgtcccac   4680

cctgatcctt ttcaatatat atttctttaa accttgtgct acttagtaaa aattgattac   4740

aattgaggga agtttgatag atcctttaaa aaaaaggcag atttccattt tttgtatttt   4800

aactacttta ctaaattaat actcctcctt ttacagaatt agaaaagtta acatttatct   4860

ttaggtggtt tcctgaaaag ttgaatattt aagaaattgt ttttaacaga agcaaaatgg   4920

cttttctttg gacagttttc accatctctt gtaaaagtta attctcacca ttcctgtggt   4980

acctgcgagt gttatgacca ggattcctta aacctgaact cagaccactt gcattagaac   5040

catctggagc acttgtttta aaatgcagat tcataggcag catctcagat ctacagaaca   5100

agaatctctg ctaagtggac ctggaatctt ccatctgcat cttaacatgc tctctaggtg   5160

tttcttgtgt ttgagaacca tgacttatga ctttcctcag aacatgagac tgtaaaacaa   5220

aaacaaaaaa ctatgtgatg cctctatttt ccccaataca gtcacacatc agctcaaaat   5280

ttgcaatatt gtagttcata tattaccgtt atgtctttgg aaatcgggtt cagaacactt   5340

tttatgacaa aaattgggtg gaggggataa ctttcatatc tggctcaaca tctcaggaaa   5400

atctgtgatt atttgtgtgt tctaatgagt aacatctact tagttagcct tagggatgga   5460

aaaacagggc cacttaccaa actcaggtga ttccaggatg gtttggaaac ttctcctgaa   5520

tgcatcctta acctttatta aaaccattgt cctaagaaca atgccaacaa agcttacaac   5580

atttagttta aacccaagaa gggcactaaa ctcagattga ctaaataaaa agtacaaagg   5640

gcacatatac gtgacagaat tgtacacaat cactccattg gatcttttac tttaaagtag   5700

tgatgaaaag tacatgttga tactgtctta gaagaaatta atatattagt gaagccacat   5760

ggggtttcag ttgcgaaaca ggtctgtttt tatgttcagt ttgtacaatc cacaattcat   5820

tcaccagata ttttgttctt aattgtgaac caggttagca aatgacctat caaaaattat   5880

tctataatca ctactagtta ggatattgat ttaaaattgt tctacttgaa gtggtttcta   5940

agatttttat attaaaaata ggtgtgattt cctaatatga tctaaaaccc taaatggtta   6000

tttttcctca gaatgatttg taaatagcta ctggaaatat tatacagtaa taggagtggg   6060

tattatgcaa catcatggag aagtgaaggc ataggcttat tctgacataa aattccactg   6120

gccagttgaa tatattctat tccatgtcca tactatgaca atcttattgt caacactata   6180

taaataagct tttaaacaag tcatttttct tgatcgttgt ggaaggtttg gagccttaga   6240

ggtatgtcag aaaaaatatg ttggtattct cccttgggta gggggaaatg acctttttac   6300

aagagagtga aatttaggtc agggaaaaga ccaagggcca gcattgctac ttttgtgtgt   6360

gtgtgtgtgg gttttgtttt gtttttttgg ttggctggtt gttttcgttg ttgttaacaa   6420

aggaatgaga atatgtaata cttaaataaa catgaccacg aagaatgctg ttctgattta   6480

ctagagaatg ttcccaattt gaatttaggg tgattttaaa gaacagtgag aaagggcata   6540

catccacaga ttcactttgt ttatgcatat gtagatacaa ggatgcacat atacacattt   6600

tcaaggacta ttttagatat ctagacaatt tcttctaata aagtcatttg tgaaagggta   6660

ctacagctta ttgacatcag taaggtagca ttcattacct gtttattctc tgctgcatct   6720

tacagaagag taaactggtg agagtatata ttttatatat atatatatat atatatatat   6780

aatatgtata tatatatata ttgacttgtt acatgaagat gttaaaatcg gtttttaaag   6840

gtgatgtaaa tagtgatttc cttaatgaaa aatacatatt ttgtattgtt ctaatgcaac   6900

agaaaagcct tttaatctct ttggttcctg tatattccat gtataagtgt aaatataatc   6960

agacaggttt aaaagttgtg catgtatgta tacagttgca agtctggaca aatgtataga   7020

ataaaccttt tatttaagtt gtgattacct gctgcatgaa aagtgcatgg gggaccctgt   7080

gcatctgtgc atttggcaaa atgtcttaac aaatcagatc agatgttcat cctaacatga   7140

cagtattcca tttctggaca tgacgtctgt ggtttaagct ttgtgaaaga atgtgctttg   7200

attcgaaggg tcttaaagaa tttttttaat cgtcaaccac ttttaaacat aaagaattca   7260

cacaactact ttcatgaatt ttttaatccc attgcaaaca ttattccaag agtatcccag   7320

tattagcaat actggaatat aggcacatta ccattcatag taagaattct ggtgtttaca   7380

caaccaaatt tgatgcgatc tgctcagtaa tataatttgc catttttatt agaaatttaa   7440

tttcttcatg tgatgtcatg aaactgtaca tactgcagtg tgaatttttt tgttttgttt   7500

tttaatcttt tagtgtttac ttcctgcagt gaatttgaat aaatgagaaa aaatgcattg   7560

tc                                                                  7562


<210>  10248
<211>  1158
<212>  PRT
<213>  Homo sapiens

<400>  10248

Met Thr His Gly Glu Glu Leu Gly Ser Asp Val His Gln Asp Ser Ile 
1               5                   10                  15


Val Leu Thr Tyr Leu Glu Gly Leu Leu Met His Gln Ala Ala Gly Gly 
            20                  25                  30


Ser Gly Thr Ala Val Asp Lys Lys Ser Ala Gly His Asn Glu Glu Asp 
        35                  40                  45


Gln Asn Phe Asn Ile Ser Gly Ser Ala Phe Pro Thr Cys Gln Ser Asn 
    50                  55                  60


Gly Pro Val Leu Asn Thr His Thr Tyr Gln Gly Ser Gly Met Leu His 
65                  70                  75                  80


Leu Lys Lys Ala Arg Leu Leu Gln Ser Ser Glu Asp Trp Asn Ala Ala 
                85                  90                  95


Lys Arg Lys Arg Leu Ser Asp Ser Ile Met Asn Leu Asn Val Lys Lys 
            100                 105                 110


Glu Ala Leu Leu Ala Gly Met Val Asp Ser Val Pro Lys Gly Lys Gln 
        115                 120                 125


Asp Ser Thr Leu Leu Ala Ser Leu Leu Gln Ser Phe Ser Ser Arg Leu 
    130                 135                 140


Gln Thr Val Ala Leu Ser Gln Gln Ile Arg Gln Ser Leu Lys Glu Gln 
145                 150                 155                 160


Gly Tyr Ala Leu Ser His Asp Ser Leu Lys Val Glu Lys Asp Leu Arg 
                165                 170                 175


Cys Tyr Gly Val Ala Ser Ser His Leu Lys Thr Leu Leu Lys Lys Ser 
            180                 185                 190


Lys Val Lys Asp Gln Lys Pro Asp Thr Asn Leu Pro Asp Val Thr Lys 
        195                 200                 205


Asn Leu Ile Arg Asp Arg Phe Ala Glu Ser Pro His His Val Gly Gln 
    210                 215                 220


Ser Gly Thr Lys Val Met Ser Glu Pro Leu Ser Cys Ala Ala Arg Leu 
225                 230                 235                 240


Gln Ala Val Ala Ser Met Val Glu Lys Arg Ala Ser Pro Ala Thr Ser 
                245                 250                 255


Pro Lys Pro Ser Val Ala Cys Ser Gln Leu Ala Leu Leu Leu Ser Ser 
            260                 265                 270


Glu Ala His Leu Gln Gln Tyr Ser Arg Glu His Ala Leu Lys Thr Gln 
        275                 280                 285


Asn Ala Asn Gln Ala Ala Ser Glu Arg Leu Ala Ala Met Ala Arg Leu 
    290                 295                 300


Gln Glu Asn Gly Gln Lys Asp Val Gly Ser Tyr Gln Leu Pro Lys Gly 
305                 310                 315                 320


Met Ser Ser His Leu Asn Gly Gln Ala Arg Thr Ser Ser Ser Lys Leu 
                325                 330                 335


Met Ala Ser Lys Ser Ser Ala Thr Val Phe Gln Asn Pro Met Gly Ile 
            340                 345                 350


Ile Pro Ser Ser Pro Lys Asn Ala Gly Tyr Lys Asn Ser Leu Glu Arg 
        355                 360                 365


Asn Asn Ile Lys Gln Ala Ala Asn Asn Ser Leu Leu Leu His Leu Leu 
    370                 375                 380


Lys Ser Gln Thr Ile Pro Lys Pro Met Asn Gly His Ser His Ser Glu 
385                 390                 395                 400


Arg Gly Ser Ile Phe Glu Glu Ser Ser Thr Pro Thr Thr Ile Asp Glu 
                405                 410                 415


Tyr Ser Asp Asn Asn Pro Ser Phe Thr Asp Asp Ser Ser Gly Asp Glu 
            420                 425                 430


Ser Ser Tyr Ser Asn Cys Val Pro Ile Asp Leu Ser Cys Lys His Arg 
        435                 440                 445


Thr Glu Lys Ser Glu Ser Asp Gln Pro Val Ser Leu Asp Asn Phe Thr 
    450                 455                 460


Gln Ser Leu Leu Asn Thr Trp Asp Pro Lys Val Pro Asp Val Asp Ile 
465                 470                 475                 480


Lys Glu Asp Gln Asp Thr Ser Lys Asn Ser Lys Leu Asn Ser His Gln 
                485                 490                 495


Lys Val Thr Leu Leu Gln Leu Leu Leu Gly His Lys Asn Glu Glu Asn 
            500                 505                 510


Val Glu Lys Asn Thr Ser Pro Gln Gly Val His Asn Asp Val Ser Lys 
        515                 520                 525


Phe Asn Thr Gln Asn Tyr Ala Arg Thr Ser Val Ile Glu Ser Pro Ser 
    530                 535                 540


Thr Asn Arg Thr Thr Pro Val Ser Thr Pro Pro Leu Leu Thr Ser Ser 
545                 550                 555                 560


Lys Ala Gly Ser Pro Ile Asn Leu Ser Gln His Ser Leu Val Ile Lys 
                565                 570                 575


Trp Asn Ser Pro Pro Tyr Val Cys Ser Thr Gln Ser Glu Lys Leu Thr 
            580                 585                 590


Asn Thr Ala Ser Asn His Ser Met Asp Leu Thr Lys Ser Lys Asp Pro 
        595                 600                 605


Pro Gly Glu Lys Pro Ala Gln Asn Glu Gly Ala Gln Asn Ser Ala Thr 
    610                 615                 620


Phe Ser Ala Ser Lys Leu Leu Gln Asn Leu Ala Gln Cys Gly Met Gln 
625                 630                 635                 640


Ser Ser Met Ser Val Glu Glu Gln Arg Pro Ser Lys Gln Leu Leu Thr 
                645                 650                 655


Gly Asn Thr Asp Lys Pro Ile Gly Met Ile Asp Arg Leu Asn Ser Pro 
            660                 665                 670


Leu Leu Ser Asn Lys Thr Asn Ala Val Glu Glu Asn Lys Ala Phe Ser 
        675                 680                 685


Ser Gln Pro Thr Gly Pro Glu Pro Gly Leu Ser Gly Ser Glu Ile Glu 
    690                 695                 700


Asn Leu Leu Glu Arg Arg Thr Val Leu Gln Leu Leu Leu Gly Asn Pro 
705                 710                 715                 720


Asn Lys Gly Lys Ser Glu Lys Lys Glu Lys Thr Pro Leu Arg Asp Glu 
                725                 730                 735


Ser Thr Gln Glu His Ser Glu Arg Ala Leu Ser Glu Gln Ile Leu Met 
            740                 745                 750


Val Lys Ile Lys Ser Glu Pro Cys Asp Asp Leu Gln Ile Pro Asn Thr 
        755                 760                 765


Asn Val His Leu Ser His Asp Ala Lys Ser Ala Pro Phe Leu Gly Met 
    770                 775                 780


Ala Pro Ala Val Gln Arg Ser Ala Pro Ala Leu Pro Val Ser Glu Asp 
785                 790                 795                 800


Phe Lys Ser Glu Pro Val Ser Pro Gln Asp Phe Ser Phe Ser Lys Asn 
                805                 810                 815


Gly Leu Leu Ser Arg Leu Leu Arg Gln Asn Gln Asp Ser Tyr Leu Ala 
            820                 825                 830


Asp Asp Ser Asp Arg Ser His Arg Asn Asn Glu Met Ala Leu Leu Glu 
        835                 840                 845


Ser Lys Asn Leu Cys Met Val Pro Lys Lys Arg Lys Leu Tyr Thr Glu 
    850                 855                 860


Pro Leu Glu Asn Pro Phe Lys Lys Met Lys Asn Asn Ile Val Asp Ala 
865                 870                 875                 880


Ala Asn Asn His Ser Ala Pro Glu Val Leu Tyr Gly Ser Leu Leu Asn 
                885                 890                 895


Gln Glu Glu Leu Lys Phe Ser Arg Asn Asp Leu Glu Phe Lys Tyr Pro 
            900                 905                 910


Ala Gly His Gly Ser Ala Ser Glu Ser Glu His Arg Ser Trp Ala Arg 
        915                 920                 925


Glu Ser Lys Ser Phe Asn Val Leu Lys Gln Leu Leu Leu Ser Glu Asn 
    930                 935                 940


Cys Val Arg Asp Leu Ser Pro His Arg Ser Asn Ser Val Ala Asp Ser 
945                 950                 955                 960


Lys Lys Lys Gly His Lys Asn Asn Val Thr Asn Ser Lys Pro Glu Phe 
                965                 970                 975


Ser Ile Ser Ser Leu Asn Gly Leu Met Tyr Ser Ser Thr Gln Pro Ser 
            980                 985                 990


Ser Cys Met Asp Asn Arg Thr Phe Ser Tyr Pro Gly Val Val Lys Thr 
        995                 1000                1005


Pro Val Ser Pro Thr Phe Pro Glu His Leu Gly Cys Ala Gly Ser Arg 
    1010                1015                1020


Pro Glu Ser Gly Leu Leu Asn Gly Cys Ser Met Pro Ser Glu Lys Gly 
1025                1030                1035                1040


Pro Ile Lys Trp Val Ile Thr Asp Ala Glu Lys Asn Glu Tyr Glu Lys 
                1045                1050                1055


Asp Ser Pro Arg Leu Thr Lys Thr Asn Pro Ile Leu Tyr Tyr Met Leu 
            1060                1065                1070


Gln Lys Gly Gly Asn Ser Val Thr Ser Arg Glu Thr Gln Asp Lys Asp 
        1075                1080                1085


Ile Trp Arg Glu Ala Ser Ser Ala Glu Ser Val Ser Gln Val Thr Ala 
    1090                1095                1100


Lys Glu Glu Leu Leu Pro Thr Ala Glu Thr Lys Ala Ser Phe Phe Asn 
1105                1110                1115                1120


Leu Arg Ser Pro Tyr Asn Ser His Met Gly Asn Asn Ala Ser Arg Pro 
                1125                1130                1135


His Ser Ala Asn Gly Glu Val Tyr Gly Leu Leu Gly Ser Val Leu Thr 
            1140                1145                1150


Ile Lys Lys Glu Ser Glu 
        1155


<210>  10249
<211>  7463
<212>  DNA
<213>  Homo sapiens

<400>  10249
gctggagact tcgcagtgac aaagcagccg aggattaacc ctgctcctgg gtcctacgtc     60

tgtccaggga gctgagcggg gcgctcctca ggaagtgttt ggattgtgag ctatttcaga    120

actgttctca ggactcatta ttttaacatt tgggagaaac acagccagaa gaacactgat    180

atttgcattt aatggggaac aaaagatgaa gaaggaaaag gaatatattc actaaggatt    240

ctatctgctt actgctacag acctatgtgt taaggaattc ttctcctcct ccttgcgtag    300

aagttgatca gcactgtggt cagactgcat ttatcttgtc attgccagaa gaaatcttgg    360

acagaatgta acagtacgtc tctctctgat tgcgatggaa ggtgataaac tgatactcct    420

ttattaaagt tacatcgcac tcaccacaga aaaccattct ttaaagtgaa tagaaaccaa    480

gcccttgtga acacttctat tgaacatgac tcatggagaa gagcttggct ctgatgtgca    540

ccaggattct attgttttaa cttacctaga aggattacta atgcatcagg cagcaggggg    600

atcaggtact gccgttgaca aaaagtctgc tgggcataat gaagaggatc agaactttaa    660

catttctggc agtgcatttc ccacctgtca aagtaatggt ccagttctca atacacatac    720

atatcagggg tctggcatgc tgcacctcaa aaaagccaga ctgttgcagt cttctgagga    780

ctggaatgca gcaaagcgga agaggctgtc tgattctatc atgaatttaa acgtaaagaa    840

ggaagctttg ctagctggca tggttgacag tgtgcctaaa ggcaaacagg atagcacatt    900

actggcctct ttgcttcagt cattcagctc taggctgcag actgttgctc tgtcacaaca    960

aatcaggcag agcctcaagg agcaaggata tgccctcagt catgattctt taaaagtgga   1020

gaaggattta aggtgctatg gtgttgcatc aagtcactta aaaactttgt tgaagaaaag   1080

taaagttaaa gatcaaaagc ctgatacgaa tcttcctgat gtgactaaaa acctcatcag   1140

agataggttt gcagagtctc ctcatcatgt tggacaaagt ggaacaaagg tcatgagtga   1200

accgttgtca tgtgctgcaa gattacaggc tgttgcaagc atggtggaaa aaagggctag   1260

tcctgccacc tcacctaaac ctagtgttgc ttgtagccag ttagcattac ttctgtcaag   1320

cgaagcccat ttgcagcagt attctcgaga acacgcttta aaaacgcaaa atgcaaatca   1380

agcagcaagt gaaagacttg ctgctatggc cagattgcaa gaaaatggcc agaaggatgt   1440

tggcagttac cagctcccaa aaggaatgtc aagccatctt aatggtcagg caagaacatc   1500

atcaagcaaa ctgatggcta gcaaaagtag tgctacagtg tttcaaaatc caatgggtat   1560

cattccttct tcccctaaaa atgcaggtta taagaactca ctggaaagaa acaatataaa   1620

acaagctgct aacaatagtt tgcttttaca tcttcttaaa agccagacta tacctaagcc   1680

aatgaatgga cacagtcaca gtgagagagg aagcattttt gaggaaagta gtacacctac   1740

aactattgat gaatattcag ataacaatcc tagttttaca gatgacagca gtggtgatga   1800

aagttcttat tccaactgtg ttcccataga cttgtcttgc aaacaccgaa ctgaaaaatc   1860

agaatctgac caacctgttt ccctggataa cttcactcaa tccttgctaa acacttggga   1920

tccaaaagtc ccagatgtag atatcaaaga agatcaagat acctcaaaga attctaagct   1980

aaactcacac cagaaagtaa cacttcttca attgctactt ggccataaga atgaagaaaa   2040

tgtagaaaaa aacaccagcc ctcagggagt acacaatgat gtgagcaagt tcaatacaca   2100

aaattatgca aggacttctg tgatagaaag ccccagtaca aatcggacta ctccagtgag   2160

cactccacct ttacttacat caagcaaagc agggtctccc atcaatctct ctcaacactc   2220

tctggtcatc aaatggaatt ccccaccata tgtctgcagt actcagtctg aaaagctaac   2280

aaatactgca tctaaccact caatggacct tacaaaaagc aaagacccac caggagagaa   2340

accagcccaa aatgaaggtg cacagaactc tgcaacgttt agtgccagta agctgttaca   2400

aaatttagca caatgtggaa tgcagtcatc catgtcagtg gaagagcaga gacccagcaa   2460

acagctgtta actggaaaca cagataaacc gataggtatg attgatagat taaatagccc   2520

tttgctctca aataaaacaa atgcagttga agaaaataaa gcatttagta gtcaaccaac   2580

aggtcctgaa ccagggcttt ctggttctga aatagaaaat ctgcttgaaa gacgtactgt   2640

cctccagttg ctcctgggga accccaacaa agggaagagt gaaaaaaaag agaaaactcc   2700

cttaagagat gaaagtactc aggaacactc agagagagct ttaagtgaac aaatactgat   2760

ggtgaaaata aaatctgagc cttgtgatga cttacaaatt cctaacacaa atgtgcactt   2820

gagccatgat gctaagagtg ccccattctt gggtatggct cctgctgtgc agagaagcgc   2880

acctgcctta ccagtgtccg aagactttaa atcggagcct gtttcacctc aggatttttc   2940

tttctccaag aatggtctgc taagtcgatt gctaagacaa aatcaagata gttacctggc   3000

agatgattca gacaggagtc acagaaataa tgaaatggca cttctagaat caaagaatct   3060

ttgcatggtc cctaagaaaa ggaagcttta tactgagcca ttagaaaatc catttaaaaa   3120

gatgaaaaac aacattgttg atgctgcaaa caatcacagt gccccagaag tactgtatgg   3180

gtccttgctt aaccaggaag agctgaaatt tagcagaaat gatcttgaat ttaaatatcc   3240

tgctggtcat ggctcagcca gcgaaagtga acacaggagt tgggccagag agagcaaaag   3300

ctttaatgtt ctgaaacagc tgcttctctc agaaaactgt gtgcgagatt tgtccccgca   3360

cagaagtaac tctgtggctg acagtaaaaa gaaaggacac aaaaataatg tgaccaacag   3420

caaacctgaa tttagcattt cttctttaaa tggactgatg tacagttcca ctcagcccag   3480

cagttgcatg gataacagga cattttcata cccaggtgta gtaaaaactc ctgtgagtcc   3540

tactttccct gagcacttgg gctgtgcagg gtctagacca gaatctgggc ttttgaatgg   3600

gtgttccatg cccagtgaga aaggacccat taagtgggtt atcactgatg cggagaagaa   3660

tgagtatgaa aaagactctc caagattgac caaaaccaac ccaatactat attacatgct   3720

tcaaaaagga ggcaattctg ttaccagtcg agaaacacaa gacaaggaca tttggaggga   3780

ggcttcatct gctgaaagtg tctcacaggt cacagccaaa gaagagttac ttcctactgc   3840

agaaacgaaa gcttctttct ttaatttaag aagcccttac aatagccata tgggaaataa   3900

tgcttctcgc ccacacagcg caaatggaga agtttatgga cttctgggaa gcgtgctaac   3960

gataaagaaa gaatcagaat aaaatgtacc tgccatccag ttttggatct ttttaaaact   4020

aatgagtatg aacttgagat ctgtataaat aagagcatga tttgaaaaaa agcatggtat   4080

aattgaaact tttttcattt tgaaaagtat tggttactgg tgatgttgaa atatgcatac   4140

taatttttgc ttaacattag atgtcatgag gaaactactg aactagcaat tggttgttta   4200

acacttctgt atgcatcaga taacaactgt gagtagccta tgaatgaaat tcttttataa   4260

atattaggca taaattaaaa tgtaaaactc cattcatagt ggattaatgc attttgctgc   4320

ctttattagg gtactttatt ttgcttttca gaagtcagcc tacataacac atttttaaag   4380

tctaaactgt taaacaactc tttaaaggat aattatccaa taaaaaaaaa cctagtgctg   4440

attcacagct tattatccaa ttcaaaaata aattagaaaa atatatgctt acatttttca   4500

cttttgctaa aaagaaaaaa aaaaggtgtt tatttttaac tcttggaaga ggttttgtgg   4560

ttcccaatgt gtctgtccca ccctgatcct tttcaatata tatttcttta aaccttgtgc   4620

tacttagtaa aaattgatta caattgaggg aagtttgata gatcctttaa aaaaaaggca   4680

gatttccatt ttttgtattt taactacttt actaaattaa tactcctcct tttacagaat   4740

tagaaaagtt aacatttatc tttaggtggt ttcctgaaaa gttgaatatt taagaaattg   4800

tttttaacag aagcaaaatg gcttttcttt ggacagtttt caccatctct tgtaaaagtt   4860

aattctcacc attcctgtgg tacctgcgag tgttatgacc aggattcctt aaacctgaac   4920

tcagaccact tgcattagaa ccatctggag cacttgtttt aaaatgcaga ttcataggca   4980

gcatctcaga tctacagaac aagaatctct gctaagtgga cctggaatct tccatctgca   5040

tcttaacatg ctctctaggt gtttcttgtg tttgagaacc atgacttatg actttcctca   5100

gaacatgaga ctgtaaaaca aaaacaaaaa actatgtgat gcctctattt tccccaatac   5160

agtcacacat cagctcaaaa tttgcaatat tgtagttcat atattaccgt tatgtctttg   5220

gaaatcgggt tcagaacact ttttatgaca aaaattgggt ggaggggata actttcatat   5280

ctggctcaac atctcaggaa aatctgtgat tatttgtgtg ttctaatgag taacatctac   5340

ttagttagcc ttagggatgg aaaaacaggg ccacttacca aactcaggtg attccaggat   5400

ggtttggaaa cttctcctga atgcatcctt aacctttatt aaaaccattg tcctaagaac   5460

aatgccaaca aagcttacaa catttagttt aaacccaaga agggcactaa actcagattg   5520

actaaataaa aagtacaaag ggcacatata cgtgacagaa ttgtacacaa tcactccatt   5580

ggatctttta ctttaaagta gtgatgaaaa gtacatgttg atactgtctt agaagaaatt   5640

aatatattag tgaagccaca tggggtttca gttgcgaaac aggtctgttt ttatgttcag   5700

tttgtacaat ccacaattca ttcaccagat attttgttct taattgtgaa ccaggttagc   5760

aaatgaccta tcaaaaatta ttctataatc actactagtt aggatattga tttaaaattg   5820

ttctacttga agtggtttct aagattttta tattaaaaat aggtgtgatt tcctaatatg   5880

atctaaaacc ctaaatggtt atttttcctc agaatgattt gtaaatagct actggaaata   5940

ttatacagta ataggagtgg gtattatgca acatcatgga gaagtgaagg cataggctta   6000

ttctgacata aaattccact ggccagttga atatattcta ttccatgtcc atactatgac   6060

aatcttattg tcaacactat ataaataagc ttttaaacaa gtcatttttc ttgatcgttg   6120

tggaaggttt ggagccttag aggtatgtca gaaaaaatat gttggtattc tcccttgggt   6180

agggggaaat gaccttttta caagagagtg aaatttaggt cagggaaaag accaagggcc   6240

agcattgcta cttttgtgtg tgtgtgtgtg ggttttgttt tgtttttttg gttggctggt   6300

tgttttcgtt gttgttaaca aaggaatgag aatatgtaat acttaaataa acatgaccac   6360

gaagaatgct gttctgattt actagagaat gttcccaatt tgaatttagg gtgattttaa   6420

agaacagtga gaaagggcat acatccacag attcactttg tttatgcata tgtagataca   6480

aggatgcaca tatacacatt ttcaaggact attttagata tctagacaat ttcttctaat   6540

aaagtcattt gtgaaagggt actacagctt attgacatca gtaaggtagc attcattacc   6600

tgtttattct ctgctgcatc ttacagaaga gtaaactggt gagagtatat attttatata   6660

tatatatata tatatatata taatatgtat atatatatat attgacttgt tacatgaaga   6720

tgttaaaatc ggtttttaaa ggtgatgtaa atagtgattt ccttaatgaa aaatacatat   6780

tttgtattgt tctaatgcaa cagaaaagcc ttttaatctc tttggttcct gtatattcca   6840

tgtataagtg taaatataat cagacaggtt taaaagttgt gcatgtatgt atacagttgc   6900

aagtctggac aaatgtatag aataaacctt ttatttaagt tgtgattacc tgctgcatga   6960

aaagtgcatg ggggaccctg tgcatctgtg catttggcaa aatgtcttaa caaatcagat   7020

cagatgttca tcctaacatg acagtattcc atttctggac atgacgtctg tggtttaagc   7080

tttgtgaaag aatgtgcttt gattcgaagg gtcttaaaga atttttttaa tcgtcaacca   7140

cttttaaaca taaagaattc acacaactac tttcatgaat tttttaatcc cattgcaaac   7200

attattccaa gagtatccca gtattagcaa tactggaata taggcacatt accattcata   7260

gtaagaattc tggtgtttac acaaccaaat ttgatgcgat ctgctcagta atataatttg   7320

ccatttttat tagaaattta atttcttcat gtgatgtcat gaaactgtac atactgcagt   7380

gtgaattttt ttgttttgtt ttttaatctt ttagtgttta cttcctgcag tgaatttgaa   7440

taaatgagaa aaaatgcatt gtc                                           7463


<210>  10250
<211>  1158
<212>  PRT
<213>  Homo sapiens

<400>  10250

Met Thr His Gly Glu Glu Leu Gly Ser Asp Val His Gln Asp Ser Ile 
1               5                   10                  15


Val Leu Thr Tyr Leu Glu Gly Leu Leu Met His Gln Ala Ala Gly Gly 
            20                  25                  30


Ser Gly Thr Ala Val Asp Lys Lys Ser Ala Gly His Asn Glu Glu Asp 
        35                  40                  45


Gln Asn Phe Asn Ile Ser Gly Ser Ala Phe Pro Thr Cys Gln Ser Asn 
    50                  55                  60


Gly Pro Val Leu Asn Thr His Thr Tyr Gln Gly Ser Gly Met Leu His 
65                  70                  75                  80


Leu Lys Lys Ala Arg Leu Leu Gln Ser Ser Glu Asp Trp Asn Ala Ala 
                85                  90                  95


Lys Arg Lys Arg Leu Ser Asp Ser Ile Met Asn Leu Asn Val Lys Lys 
            100                 105                 110


Glu Ala Leu Leu Ala Gly Met Val Asp Ser Val Pro Lys Gly Lys Gln 
        115                 120                 125


Asp Ser Thr Leu Leu Ala Ser Leu Leu Gln Ser Phe Ser Ser Arg Leu 
    130                 135                 140


Gln Thr Val Ala Leu Ser Gln Gln Ile Arg Gln Ser Leu Lys Glu Gln 
145                 150                 155                 160


Gly Tyr Ala Leu Ser His Asp Ser Leu Lys Val Glu Lys Asp Leu Arg 
                165                 170                 175


Cys Tyr Gly Val Ala Ser Ser His Leu Lys Thr Leu Leu Lys Lys Ser 
            180                 185                 190


Lys Val Lys Asp Gln Lys Pro Asp Thr Asn Leu Pro Asp Val Thr Lys 
        195                 200                 205


Asn Leu Ile Arg Asp Arg Phe Ala Glu Ser Pro His His Val Gly Gln 
    210                 215                 220


Ser Gly Thr Lys Val Met Ser Glu Pro Leu Ser Cys Ala Ala Arg Leu 
225                 230                 235                 240


Gln Ala Val Ala Ser Met Val Glu Lys Arg Ala Ser Pro Ala Thr Ser 
                245                 250                 255


Pro Lys Pro Ser Val Ala Cys Ser Gln Leu Ala Leu Leu Leu Ser Ser 
            260                 265                 270


Glu Ala His Leu Gln Gln Tyr Ser Arg Glu His Ala Leu Lys Thr Gln 
        275                 280                 285


Asn Ala Asn Gln Ala Ala Ser Glu Arg Leu Ala Ala Met Ala Arg Leu 
    290                 295                 300


Gln Glu Asn Gly Gln Lys Asp Val Gly Ser Tyr Gln Leu Pro Lys Gly 
305                 310                 315                 320


Met Ser Ser His Leu Asn Gly Gln Ala Arg Thr Ser Ser Ser Lys Leu 
                325                 330                 335


Met Ala Ser Lys Ser Ser Ala Thr Val Phe Gln Asn Pro Met Gly Ile 
            340                 345                 350


Ile Pro Ser Ser Pro Lys Asn Ala Gly Tyr Lys Asn Ser Leu Glu Arg 
        355                 360                 365


Asn Asn Ile Lys Gln Ala Ala Asn Asn Ser Leu Leu Leu His Leu Leu 
    370                 375                 380


Lys Ser Gln Thr Ile Pro Lys Pro Met Asn Gly His Ser His Ser Glu 
385                 390                 395                 400


Arg Gly Ser Ile Phe Glu Glu Ser Ser Thr Pro Thr Thr Ile Asp Glu 
                405                 410                 415


Tyr Ser Asp Asn Asn Pro Ser Phe Thr Asp Asp Ser Ser Gly Asp Glu 
            420                 425                 430


Ser Ser Tyr Ser Asn Cys Val Pro Ile Asp Leu Ser Cys Lys His Arg 
        435                 440                 445


Thr Glu Lys Ser Glu Ser Asp Gln Pro Val Ser Leu Asp Asn Phe Thr 
    450                 455                 460


Gln Ser Leu Leu Asn Thr Trp Asp Pro Lys Val Pro Asp Val Asp Ile 
465                 470                 475                 480


Lys Glu Asp Gln Asp Thr Ser Lys Asn Ser Lys Leu Asn Ser His Gln 
                485                 490                 495


Lys Val Thr Leu Leu Gln Leu Leu Leu Gly His Lys Asn Glu Glu Asn 
            500                 505                 510


Val Glu Lys Asn Thr Ser Pro Gln Gly Val His Asn Asp Val Ser Lys 
        515                 520                 525


Phe Asn Thr Gln Asn Tyr Ala Arg Thr Ser Val Ile Glu Ser Pro Ser 
    530                 535                 540


Thr Asn Arg Thr Thr Pro Val Ser Thr Pro Pro Leu Leu Thr Ser Ser 
545                 550                 555                 560


Lys Ala Gly Ser Pro Ile Asn Leu Ser Gln His Ser Leu Val Ile Lys 
                565                 570                 575


Trp Asn Ser Pro Pro Tyr Val Cys Ser Thr Gln Ser Glu Lys Leu Thr 
            580                 585                 590


Asn Thr Ala Ser Asn His Ser Met Asp Leu Thr Lys Ser Lys Asp Pro 
        595                 600                 605


Pro Gly Glu Lys Pro Ala Gln Asn Glu Gly Ala Gln Asn Ser Ala Thr 
    610                 615                 620


Phe Ser Ala Ser Lys Leu Leu Gln Asn Leu Ala Gln Cys Gly Met Gln 
625                 630                 635                 640


Ser Ser Met Ser Val Glu Glu Gln Arg Pro Ser Lys Gln Leu Leu Thr 
                645                 650                 655


Gly Asn Thr Asp Lys Pro Ile Gly Met Ile Asp Arg Leu Asn Ser Pro 
            660                 665                 670


Leu Leu Ser Asn Lys Thr Asn Ala Val Glu Glu Asn Lys Ala Phe Ser 
        675                 680                 685


Ser Gln Pro Thr Gly Pro Glu Pro Gly Leu Ser Gly Ser Glu Ile Glu 
    690                 695                 700


Asn Leu Leu Glu Arg Arg Thr Val Leu Gln Leu Leu Leu Gly Asn Pro 
705                 710                 715                 720


Asn Lys Gly Lys Ser Glu Lys Lys Glu Lys Thr Pro Leu Arg Asp Glu 
                725                 730                 735


Ser Thr Gln Glu His Ser Glu Arg Ala Leu Ser Glu Gln Ile Leu Met 
            740                 745                 750


Val Lys Ile Lys Ser Glu Pro Cys Asp Asp Leu Gln Ile Pro Asn Thr 
        755                 760                 765


Asn Val His Leu Ser His Asp Ala Lys Ser Ala Pro Phe Leu Gly Met 
    770                 775                 780


Ala Pro Ala Val Gln Arg Ser Ala Pro Ala Leu Pro Val Ser Glu Asp 
785                 790                 795                 800


Phe Lys Ser Glu Pro Val Ser Pro Gln Asp Phe Ser Phe Ser Lys Asn 
                805                 810                 815


Gly Leu Leu Ser Arg Leu Leu Arg Gln Asn Gln Asp Ser Tyr Leu Ala 
            820                 825                 830


Asp Asp Ser Asp Arg Ser His Arg Asn Asn Glu Met Ala Leu Leu Glu 
        835                 840                 845


Ser Lys Asn Leu Cys Met Val Pro Lys Lys Arg Lys Leu Tyr Thr Glu 
    850                 855                 860


Pro Leu Glu Asn Pro Phe Lys Lys Met Lys Asn Asn Ile Val Asp Ala 
865                 870                 875                 880


Ala Asn Asn His Ser Ala Pro Glu Val Leu Tyr Gly Ser Leu Leu Asn 
                885                 890                 895


Gln Glu Glu Leu Lys Phe Ser Arg Asn Asp Leu Glu Phe Lys Tyr Pro 
            900                 905                 910


Ala Gly His Gly Ser Ala Ser Glu Ser Glu His Arg Ser Trp Ala Arg 
        915                 920                 925


Glu Ser Lys Ser Phe Asn Val Leu Lys Gln Leu Leu Leu Ser Glu Asn 
    930                 935                 940


Cys Val Arg Asp Leu Ser Pro His Arg Ser Asn Ser Val Ala Asp Ser 
945                 950                 955                 960


Lys Lys Lys Gly His Lys Asn Asn Val Thr Asn Ser Lys Pro Glu Phe 
                965                 970                 975


Ser Ile Ser Ser Leu Asn Gly Leu Met Tyr Ser Ser Thr Gln Pro Ser 
            980                 985                 990


Ser Cys Met Asp Asn Arg Thr Phe Ser Tyr Pro Gly Val Val Lys Thr 
        995                 1000                1005


Pro Val Ser Pro Thr Phe Pro Glu His Leu Gly Cys Ala Gly Ser Arg 
    1010                1015                1020


Pro Glu Ser Gly Leu Leu Asn Gly Cys Ser Met Pro Ser Glu Lys Gly 
1025                1030                1035                1040


Pro Ile Lys Trp Val Ile Thr Asp Ala Glu Lys Asn Glu Tyr Glu Lys 
                1045                1050                1055


Asp Ser Pro Arg Leu Thr Lys Thr Asn Pro Ile Leu Tyr Tyr Met Leu 
            1060                1065                1070


Gln Lys Gly Gly Asn Ser Val Thr Ser Arg Glu Thr Gln Asp Lys Asp 
        1075                1080                1085


Ile Trp Arg Glu Ala Ser Ser Ala Glu Ser Val Ser Gln Val Thr Ala 
    1090                1095                1100


Lys Glu Glu Leu Leu Pro Thr Ala Glu Thr Lys Ala Ser Phe Phe Asn 
1105                1110                1115                1120


Leu Arg Ser Pro Tyr Asn Ser His Met Gly Asn Asn Ala Ser Arg Pro 
                1125                1130                1135


His Ser Ala Asn Gly Glu Val Tyr Gly Leu Leu Gly Ser Val Leu Thr 
            1140                1145                1150


Ile Lys Lys Glu Ser Glu 
        1155


<210>  10251
<211>  751
<212>  DNA
<213>  Homo sapiens

<400>  10251
actgaactcc caatctgctt caagatctgt cttaggattg gtgaattatg ttcattttta     60

aaaagggatg tgatagacaa catctagaga aacaggcaag gagtatatat ctgaaaagga    120

caaggcgctt tgaaactgac agctcatcaa caggttcatg gatgaacctg gaaatattta    180

taaatattga ttccagattt cagagacggg gtttcgaaat gttgcccagg ttggtctaga    240

actcccggac tcaagtgatc ccccgaccag gcctcccaaa gtgctgggat tatcggtgtg    300

agccaccaac ccctgcagag tctacatctg aaataaacca cagaagcaag gatatcactt    360

aaacaatgta acttaccaat tcagtctgag tgagttttgt agtttataac atattgatga    420

aaacagttaa gtgtccacat tccgtttaca taagagaatg ctattcaagc ttttaaaata    480

aaaaacttaa actattcccc tcacccccca aaaagtctaa ctataaagat gggtttgcta    540

caaaataatt agcaaaactg atttaccaag taagatgtcc tcccgctcac tgccccccag    600

aaatacgtat actgtaggaa tactcctagg aagtgacaca agtgaaagaa agaatattct    660

ttcaatatgc taaaaacatc tacagtgcac taaaaaaaag tccctaaatt tggcaataca    720

tttcttccaa aaatgttatt caataacata a                                   751


<210>  10252
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  10252

Met Phe Ile Phe Lys Lys Gly Cys Asp Arg Gln His Leu Glu Lys Gln 
1               5                   10                  15


Ala Arg Ser Ile Tyr Leu Lys Arg Thr Arg Arg Phe Glu Thr Asp Ser 
            20                  25                  30


Ser Ser Thr Gly Ser Trp Met Asn Leu Glu Ile Phe Ile Asn Ile Asp 
        35                  40                  45


Ser Arg Phe Gln Arg Arg Gly Phe Glu Met Leu Pro Arg Leu Val 
    50                  55                  60


<210>  10253
<211>  498
<212>  DNA
<213>  Homo sapiens

<400>  10253
gctgaagaag tagcagccct gctccttttc ccttgtcttg ttgggtcaga tccttcccgg     60

ggatgatgca gattggctga cagactccgc tggagacttc gcagtgacaa agcagccgag    120

gattaaccct gctcctgggt cctacgtctg tccagggagc tgagcggggc gctcctcagg    180

aagtgtttgg attgtgagct atttcagaac tgttctcagg actcattatt ttaacatttg    240

ggagaaacac agccagaagc tgaaaaaact gagcctcgga acagttaagt aaatccacca    300

aagtgaccca ctactgaata gcagagtcag gaatccagag actgttcttt tcaccacaat    360

gctttgtggc cttcctaata aaagcaagag actgacactg gcagagacaa gattttagag    420

tgggaaaagt aatccagaat tctcagagtg ctgcataaat tttgctttac gaaaagtttt    480

caaatccaca tttgttac                                                  498


<210>  10254
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  10254

Ala Gly Arg Ser Ser Gly Ser Val Trp Ile Val Ser Tyr Phe Arg Thr 
1               5                   10                  15


Val Leu Arg Thr His Tyr Phe Asn Ile Trp Glu Lys His Ser Gln Lys 
            20                  25                  30


Leu Lys Lys Leu Ser Leu Gly Thr Val Lys 
        35                  40


<210>  10255
<211>  573
<212>  DNA
<213>  Homo sapiens

<400>  10255
atttcttatt cggagaccga accgaggaga gctgctgaag aagtagcagc cctgctcctt     60

ttcccttgtc ttgttgggtc agatccttcc cggggatgat gcagattggc tgacagactc    120

cgctggagac ttcgcagtga caaagcagcc gaggattaac cctgctcctg ggtcctacgt    180

ctgtccaggg agctgagcgg ggcgctcctc aggaagtgtt tggattgtga gctatttcag    240

aactgttctc aggactcatt attttaacat ttgggagaaa cacagccaga agatgcacac    300

ttgactgaag gaggacaggg aatctgaaga ctccggatga catcagagct acttttcaac    360

agccttctca attttctttc tcagaaagca gaggctcaga gcttggagac agacgcccca    420

gagttccaaa agttggtttg catggacaga ttcagagcag tcccacagag cccaggtcct    480

gttaataaga agaggcatgt tacatgatac gcacaaagaa actgaaaaaa ctgagcctcg    540

gaacagttaa gtaaatccac caaagtgacc cac                                 573


<210>  10256
<211>  56
<212>  PRT
<213>  Homo sapiens

<400>  10256

Met Thr Ser Glu Leu Leu Phe Asn Ser Leu Leu Asn Phe Leu Ser Gln 
1               5                   10                  15


Lys Ala Glu Ala Gln Ser Leu Glu Thr Asp Ala Pro Glu Phe Gln Lys 
            20                  25                  30


Leu Val Cys Met Asp Arg Phe Arg Ala Val Pro Gln Ser Pro Gly Pro 
        35                  40                  45


Val Asn Lys Lys Arg His Val Thr 
    50                  55


<210>  10257
<211>  446
<212>  DNA
<213>  Homo sapiens

<400>  10257
agtaattatt gtagtaggtt gtagcggatt cagtaaatat atccagttcc tattctatat     60

tctttctagg tgttaggaat gctcccagga ggtacaaaag ctatcagtcg ctgcaccgaa    120

ggactctagg atgctatgac ttagttttgg accatggaga ttgcccagca agccgagaat    180

attccagccc tccaacattg ttgttaaaaa gtccactgct gtatgttagg tgacttccca    240

aagctgctca ctacttcttc ttattctgtt ttctcaaccc cacaaaaatc caatcactga    300

aatcctgaac tcttttgata gtggcatgag tgttaagtaa attgcacacc tcttgtggaa    360

ttcattttca cttaatcatg ctaattatgt ggagacttgt ttgttgttgt tctttgtttt    420

tttaagtaaa tcaataccta aatttc                                         446


<210>  10258
<211>  71
<212>  PRT
<213>  Homo sapiens

<400>  10258

Val Val Ala Asp Ser Val Asn Ile Ser Ser Ser Tyr Ser Ile Phe Phe 
1               5                   10                  15


Leu Gly Val Arg Asn Ala Pro Arg Arg Tyr Lys Ser Tyr Gln Ser Leu 
            20                  25                  30


His Arg Arg Thr Leu Gly Cys Tyr Asp Leu Val Leu Asp His Gly Asp 
        35                  40                  45


Cys Pro Ala Ser Arg Glu Tyr Ser Ser Pro Pro Thr Leu Leu Leu Lys 
    50                  55                  60


Ser Pro Leu Leu Tyr Val Arg 
65                  70


<210>  10259
<211>  762
<212>  DNA
<213>  Homo sapiens

<400>  10259
aactaggaca actaatatgc ttcaaacttc caatgataat gtatagacaa gaagacagct     60

ctgtcctcta ggctgtgctt ttagtgccaa ctttcttaat aacatcacct attctgctga    120

cactcactct ggaggaataa aactttagag cccctggcta aacaggatct gagaggaagg    180

ttggaatcca gtggcagtat cgtggctcac tgcaacctca acctgccact ctcatgccat    240

ccaaccacct cagcctccct agtagctggg actacaggta tacgccacaa tgcccaggtt    300

tttactcctg ggtctgaaaa agtcatcaaa tcttggtaat tcttagacac tgacatcagt    360

caaagcctca tctgcagacc taggagaagg tgataataaa aatgaactgc ttttgtgaga    420

cacggggcca gaaattaaaa ctgttcaatt gctctaggcc caagcattat ttcagaagag    480

gctggcatga agtggctcaa tctcagctca ctgcaacctc cacctcaagg attgaagcga    540

ttctcatgcc tcagactccc cagtagctgg ggttacaggt caaaaactac taccgcaatg    600

agtgggaagt cagatgatta atgtctgctg tttacacaga aacttgcaga gatttacagc    660

aagagcataa gtatatcaag atgacaataa caacaatgtt taacatctag aagccacttc    720

caacaaaacc atgtggaagg cgggagcaaa ttgcatagat gt                       762


<210>  10260
<211>  54
<212>  PRT
<213>  Homo sapiens

<400>  10260

Met Asn Cys Phe Cys Glu Thr Arg Gly Gln Lys Leu Lys Leu Phe Asn 
1               5                   10                  15


Cys Ser Arg Pro Lys His Tyr Phe Arg Arg Gly Trp His Glu Val Ala 
            20                  25                  30


Gln Ser Gln Leu Thr Ala Thr Ser Thr Ser Arg Ile Glu Ala Ile Leu 
        35                  40                  45


Met Pro Gln Thr Pro Gln 
    50


<210>  10261
<211>  2884
<212>  DNA
<213>  Homo sapiens

<400>  10261
aggcggttgc tacccacctg ctagaggcgc tgcggctgtg atccaggctg gggcgagacc     60

atgtcggacc tgggctcgga ggagttggag gaggagggag agaatgatat tggggaatat    120

gaggggggtc ggaatgaggc aggcgaaagg cacggacgtg ggagggcacg gctacccaac    180

ggggacacct acgaagggag ctacgaattc ggtaaaagac atggccaggg gatctacaaa    240

tttaaaaatg gtgctcgata tatcggagaa tatgttagaa ataaaaagca cggtcaaggc    300

acttttatat atccagatgg atccagatat gaaggagagt gggcaaatga cctgcggcac    360

ggccatggcg tatactacta catcaataat gacacctaca ctggagagtg gtttgctcat    420

caaaggttcg gtttctatct tgggtcttaa cgggatttgc ttatgtaatg agaacatgat    480

gtctgcagat tgtttacact tactgaggaa cagaatcata acaaaagccc agttaccaac    540

tctgccaggc aggtccaatc tttctatggc tttgaggcaa ggatgccttt ctgtgcaagt    600

gtagactcaa gtatctgaca tctgcacctc agttggggca gagcacgtga gtctttcacc    660

caagagtccc agggagtgga gggcacagaa gagccactgg gggacctgag ccacagctcc    720

cactagctct gcctcttccc tggggaaagc agctgacaca caggaggctt gcctctgtcc    780

agctggcctg tcctctgtgc ctctggcaat gtcctgtgct tggggcacac tgagcaaggg    840

gcaccttctg actggacaca gatatagaag ctacatcgct tgtgagcctg caacagcctg    900

ggcctccctc aatgtcaatg tctgtgtttt aaacctggga gatttttcac tgtgctggaa    960

cgaaatacca tgttcccctt gtcttaacca ggcatgggca aggcacctat ttatacgcgg   1020

agacgggcag taagtatgtt ggcacctggg tgaacggaca gcaggagggc acggccgagc   1080

tcattcacct gaaccacagg taccagggca agttcttgaa caaaaatgta agtccatggg   1140

aagtgacatt tgccaatgaa gtacaaaata accccctctg gcagcctgtg caaatgtgtg   1200

accagagaat accaaaaact cagagaaaac tgagtccggc ctattcaaat gtggagaaca   1260

ggacagctgt gccattctct gagcctctgg tacccacaga gcacagaatt gggggaaggg   1320

agggattggc ccgtttctct ggatctcagt acaaattccc actgtctttc agcggggacc   1380

tgttgcattg ttatataaca cgagagggca tctgaacctc ttgtgtgtat tccttctcat   1440

gggtaaatca gataccaaat atctatttcc tgcaattgag catagaggtg tttgggtttt   1500

gtttccctgg aaggggaggt gcgacatccc tggggaggaa gacccccagc tccctcctca   1560

tgctacaggc cagcctgcgt gctcctagtt gtggtgggaa ttaaggctgc caagggcctg   1620

gccctgcgtc tggaggcttg ccagcttcta gcacccatgg tgggccgttt ctgtttggaa   1680

gactcggtgg ttcctcttgc ccttattgta cagagaaacc ttgaataatt cagaagctaa   1740

tactcaggcc atcgtggtag ctttgatcag gggttgagca gaaactttcc ctgaagagag   1800

aatttgcgga gcaaattgat ggtgttagaa gttgacagag ggaatgttta gctgatacaa   1860

cgaagtctct tcagactctc ttagaaccca gttttcattt acgtataatt catgccctaa   1920

ccacagattt tacttttagt tttcatcaaa acagcacatt cccctcaaac ccatacattg   1980

tttatataat tcccagcaaa ctttctgtgg gtctttttgg aggagatggg aaggtggttg   2040

cagaggaaga gaatttgatg aaaatgaatc tggaagaatc aatcagcttg tccagcctaa   2100

accagtctga aaaatcgggc ctgttggccc tggaaagtat gtatttgatg ttgggtgtga   2160

acaacatggt gaatatcgtt taacagatat ggaaagagga gaagaggaag aggaggaaga   2220

attagtaact gttgttccaa aatggaaagc tacccaaatc actgaattgg ccctgtggac   2280

accaactctc cccaaaaagc cgacctctac ggatggacct ggccaagacg ctccaggagc   2340

tgagagtgca ggagaacccg gggaggaggc ccaggctctg ctggagggct tcgagggtga   2400

gatggacatg aggcctggag atgaagatgc agacgtcctc cgggaagaga gccgggagta   2460

tgaccaggag gagttccgct atgacatgga tgagggaaac attaattctg aagaagaaga   2520

aactagacag tcagacctcc aggactaaga tgaagtgagc cgagaggaga tcgtatcata   2580

agaatgcttc tgtcgttagc cgggtgcagt gctgtgtgta tctagttcca gctacttgag   2640

aggctgaggc aggaggattg cttgagtcca gaaagtggca gttgcagtga gtggagatcg   2700

cgccactgct ctccagcctg ggtggcagag cgagaccctg tctcaaaaaa taaacaaaaa   2760

caaaatgctt ctgtcagtta acaatcttta ttagagggtt tttagtcttt ctttctcagc   2820

tgtatgttaa gttgattgac aaatgcaaat aaacgtcttt attatccttt ctttctgaaa   2880

tagc                                                                2884


<210>  10262
<211>  166
<212>  PRT
<213>  Homo sapiens

<400>  10262

Met Ile Leu Gly Asn Met Arg Gly Val Gly Met Arg Gln Ala Lys Gly 
1               5                   10                  15


Thr Asp Val Gly Gly His Gly Tyr Pro Thr Gly Thr Pro Thr Lys Gly 
            20                  25                  30


Ala Thr Asn Ser Val Lys Asp Met Ala Arg Gly Ser Thr Asn Leu Lys 
        35                  40                  45


Met Val Leu Asp Ile Ser Glu Asn Met Leu Glu Ile Lys Ser Thr Val 
    50                  55                  60


Lys Ala Leu Leu Tyr Ile Gln Met Asp Pro Asp Met Lys Glu Ser Gly 
65                  70                  75                  80


Gln Met Thr Cys Gly Thr Ala Met Ala Tyr Thr Thr Thr Ser Ile Met 
                85                  90                  95


Thr Pro Thr Leu Glu Ser Gly Leu Leu Ile Lys Gly Ser Val Ser Ile 
            100                 105                 110


Leu Gly Leu Asn Gly Ile Cys Leu Cys Asn Glu Asn Met Met Ser Ala 
        115                 120                 125


Asp Cys Leu His Leu Leu Arg Asn Arg Ile Ile Thr Lys Ala Gln Leu 
    130                 135                 140


Pro Thr Leu Pro Gly Arg Ser Asn Leu Ser Met Ala Leu Arg Gln Gly 
145                 150                 155                 160


Cys Leu Ser Val Gln Val 
                165


<210>  10263
<211>  1434
<212>  DNA
<213>  Homo sapiens

<400>  10263
tggctcctcc cgcttcgtcc gcgtcgcctg tccccgctcc ccatcttccg ggctgggagg     60

gaggcgggac cggccgcgtc tccatggcga cgcgggacgc ggcggtggag gcggttgcta    120

cccacctgct agaggcgctg cggctgtgat ccaggctggg gcgagaccat gtcggacctg    180

ggctcggagg agttggagga ggagggagag aatgatattg gggaatatga ggggggtcgg    240

aatgaggcag gcgaaaggca cggacgtggg agggcacggc tacccaacgg ggacacctac    300

gaagggagct acgaattcgg taaaagacat ggccagggga tctacaaatt taaaaatggt    360

gctcgatata tcggagaata tgttagaaat aaaaagcacg gtcaaggcac ttttatatat    420

ccagatggat ccagatatga aggagagtgg gcaaatgacc tgcggcacgg ccatggcgta    480

tactactaca tcaataatga cacctacact ggagagtggt ttgctcatca aaggcatggg    540

caaggcacct atttatacgc ggagacgggc agtaagtatg ttggcacctg ggtgaacgga    600

cagcaggagg gcacggccga gctcattcac ctgaaccaca ggtaccaggg caagttcttg    660

aacaaaaatc ctgttggccc tggaaagtat gtatttgatg ttgggtgtga acaacatggt    720

gaatatcgtt taacagatat ggaaagagga gaagaggaag aggaggaaga attagtaact    780

gttgttccaa aatggaaagc tacccaaatc actgaattgg ccctgtggac accaactctc    840

cccaaaaagc cgacctctac ggatggacct ggccaagacg ctccaggagc tgagagtgca    900

ggagaacccg gggaggaggc ccaggctctg ctggagggct tcgagggtga gatggacatg    960

aggcctggag atgaagatgc agacgtcctc cgggaagaga gccgggagta tgaccaggag   1020

gagttccgct atgacatgga tgagggaaac attaattctg aagaagaaga aactagacag   1080

tcagacctcc aggactaaga tgaagtgagc cgagaggaga tcgtatcata agaatgcttc   1140

tgtcgttagc cgggtgcagt gctgtgtgta tctagttcca gctacttgag aggctgaggc   1200

aggaggattg cttgagtcca gaaagtggca gttgcagtga gtggagatcg cgccactgct   1260

ctccagcctg ggtggcagag cgagaccctg tctcaaaaaa taaacaaaaa caaaatgctt   1320

ctgtcagtta acaatcttta ttagagggtt tttagtcttt ctttctcagc tgtatgttaa   1380

gttgattgac aaatgcaaat aaacgtcttt attatccttt ctttctgaaa tagc         1434


<210>  10264
<211>  309
<212>  PRT
<213>  Homo sapiens

<400>  10264

Met Ser Asp Leu Gly Ser Glu Glu Leu Glu Glu Glu Gly Glu Asn Asp 
1               5                   10                  15


Ile Gly Glu Tyr Glu Gly Gly Arg Asn Glu Ala Gly Glu Arg His Gly 
            20                  25                  30


Arg Gly Arg Ala Arg Leu Pro Asn Gly Asp Thr Tyr Glu Gly Ser Tyr 
        35                  40                  45


Glu Phe Gly Lys Arg His Gly Gln Gly Ile Tyr Lys Phe Lys Asn Gly 
    50                  55                  60


Ala Arg Tyr Ile Gly Glu Tyr Val Arg Asn Lys Lys His Gly Gln Gly 
65                  70                  75                  80


Thr Phe Ile Tyr Pro Asp Gly Ser Arg Tyr Glu Gly Glu Trp Ala Asn 
                85                  90                  95


Asp Leu Arg His Gly His Gly Val Tyr Tyr Tyr Ile Asn Asn Asp Thr 
            100                 105                 110


Tyr Thr Gly Glu Trp Phe Ala His Gln Arg His Gly Gln Gly Thr Tyr 
        115                 120                 125


Leu Tyr Ala Glu Thr Gly Ser Lys Tyr Val Gly Thr Trp Val Asn Gly 
    130                 135                 140


Gln Gln Glu Gly Thr Ala Glu Leu Ile His Leu Asn His Arg Tyr Gln 
145                 150                 155                 160


Gly Lys Phe Leu Asn Lys Asn Pro Val Gly Pro Gly Lys Tyr Val Phe 
                165                 170                 175


Asp Val Gly Cys Glu Gln His Gly Glu Tyr Arg Leu Thr Asp Met Glu 
            180                 185                 190


Arg Gly Glu Glu Glu Glu Glu Glu Glu Leu Val Thr Val Val Pro Lys 
        195                 200                 205


Trp Lys Ala Thr Gln Ile Thr Glu Leu Ala Leu Trp Thr Pro Thr Leu 
    210                 215                 220


Pro Lys Lys Pro Thr Ser Thr Asp Gly Pro Gly Gln Asp Ala Pro Gly 
225                 230                 235                 240


Ala Glu Ser Ala Gly Glu Pro Gly Glu Glu Ala Gln Ala Leu Leu Glu 
                245                 250                 255


Gly Phe Glu Gly Glu Met Asp Met Arg Pro Gly Asp Glu Asp Ala Asp 
            260                 265                 270


Val Leu Arg Glu Glu Ser Arg Glu Tyr Asp Gln Glu Glu Phe Arg Tyr 
        275                 280                 285


Asp Met Asp Glu Gly Asn Ile Asn Ser Glu Glu Glu Glu Thr Arg Gln 
    290                 295                 300


Ser Asp Leu Gln Asp 
305


<210>  10265
<211>  568
<212>  DNA
<213>  Homo sapiens

<400>  10265
ggggagctgt ggctcagacc tctggtttct gcgcctcctc actctccaaa cccaacctcg     60

aggttccccc gccgctgcgc accctgggaa gccctttctc accaggagct ctcaccccaa    120

tatcattctc tccctcctcc tccaactcct ccgagcccag gtccgacatg gtctcgcccc    180

agcctggatc acagccgcag cgcctctagc agctttatag aattgagaga ttgctgagcc    240

taaatacatg ttgctgcatt gcctccgaga atggccggac ctatccccac tctcaccaaa    300

acagagtgtg ggactcactg ctccctcgcc tactagagca gagccactgc cagaaggaag    360

gggacaagac ccagcaggac accttctttc cacgctttcc agcctgtggg agcggcaggg    420

gcaacagaga gaggatctgg agccaggatt aatgactcat ttatgaagca tcttattctg    480

cgaccgaggc tcagtggtca gtggcgacgt aaatggctcg actccccgct ggcattcgct    540

tcatcatctc attctccagg gatcagtg                                       568


<210>  10266
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  10266

Met Leu Leu His Cys Leu Arg Glu Trp Pro Asp Leu Ser Pro Leu Ser 
1               5                   10                  15


Pro Lys Gln Ser Val Gly Leu Thr Ala Pro Ser Pro Thr Arg Ala Glu 
            20                  25                  30


Pro Leu Pro Glu Gly Arg Gly Gln Asp Pro Ala Gly His Leu Leu Ser 
        35                  40                  45


Thr Leu Ser Ser Leu Trp Glu Arg Gln Gly Gln Gln Arg Glu Asp Leu 
    50                  55                  60


Glu Pro Gly Leu Met Thr His Leu 
65                  70


<210>  10267
<211>  604
<212>  DNA
<213>  Homo sapiens

<400>  10267
atggagacgc ggccggtccc gcctccctcc cagcccggaa gatggggagc ggggacaggc     60

gacgcggacg aagcgggagg agccactggc agcctttgcc aacgaggggc cgcttcggcc    120

aatcactgct cgggaagcga gggggcgggg actgggcagg gcctgagcgg gttctgtgcc    180

tggctgccca ccggctctct gacctggacc tcgccgtcgc tggcccctga aatccatcac    240

ttttgtcggc tgttctgtga cgccacaacg aggagccacc tgggctctgc tgacccttcg    300

ggattcgcgg ctagctgtga tgtgtccgcc aagatctctt ctcttgtctg taaacaactt    360

cactctcaag gaggcagctc tggcctctca gcaggagctg gggaggagtg actgaataac    420

tataggattt ggtcttgatg ggagaatccc agaagccaaa tccacgcggt gaataagctg    480

ctgatcttcc agagcacaca tcccctagag attcttccca atgctaatat gaaaggttac    540

aaccataacc catcatcagg cccaaatata ttacttactg aataaataca caagttacaa    600

caac                                                                 604


<210>  10268
<211>  136
<212>  PRT
<213>  Homo sapiens

<400>  10268

Met Glu Thr Arg Pro Val Pro Pro Pro Ser Gln Pro Gly Arg Trp Gly 
1               5                   10                  15


Ala Gly Thr Gly Asp Ala Asp Glu Ala Gly Gly Ala Thr Gly Ser Leu 
            20                  25                  30


Cys Gln Arg Gly Ala Ala Ser Ala Asn His Cys Ser Gly Ser Glu Gly 
        35                  40                  45


Ala Gly Thr Gly Gln Gly Leu Ser Gly Phe Cys Ala Trp Leu Pro Thr 
    50                  55                  60


Gly Ser Leu Thr Trp Thr Ser Pro Ser Leu Ala Pro Glu Ile His His 
65                  70                  75                  80


Phe Cys Arg Leu Phe Cys Asp Ala Thr Thr Arg Ser His Leu Gly Ser 
                85                  90                  95


Ala Asp Pro Ser Gly Phe Ala Ala Ser Cys Asp Val Ser Ala Lys Ile 
            100                 105                 110


Ser Ser Leu Val Cys Lys Gln Leu His Ser Gln Gly Gly Ser Ser Gly 
        115                 120                 125


Leu Ser Ala Gly Ala Gly Glu Glu 
    130                 135


<210>  10269
<211>  3097
<212>  DNA
<213>  Homo sapiens

<400>  10269
aagtgggaag ttcgcgcaag tgcggctctg cagggaggag ggagggccga ggggaaggcc     60

ctcgagagag tggagggcaa cagtggccac ggttcctctg tacttcgttt cttcccttta    120

tagaattgag agattgctga gcctaaatac atgttgctgc attgcctccg agaatggccg    180

gacctatccc cactctcacc aaaacagagt gtgggactca ctgctccctc gcctactaga    240

gcagagccac tgccagaagg aaggggacaa gacccagcag gacaccttct ttccacgctt    300

tccagcctgt gggagcggca ggggcaacag agagaggatc tggagccagg attaatgact    360

catttatgaa gcatcttatt ctgcgaccga ggctcagtgg tcagtggcga cgtaaatggc    420

tcgactcccc gctggcattc gcttcatcat ctcattctcc agggatcagt ggtacagagc    480

cttcattttt attttgacat ttctgctgta tgcaagtttt cacttatctc gaaagcctat    540

cagcatagtt aagggtgagc tccacaagta ctgcactgct tgggatgaag ctgacgtcag    600

gttcagcagc cagaacagga agtctgggtc cgctgccccc caccagctcc ctgacaatga    660

gaccgactgt ggctgggcac cgtttgataa gaacaactat cagcagctgc ttggggccct    720

ggactactcc ttcctgtgcg cctatgccgt ggggatgtac ctcagtggca tcattgggga    780

gcgcctgccg attaggtatt acctaacttt cgggatgctc gccagcggag ccttcaccgc    840

cctgttcggc ttagggtatt tctacaacat ccacagtttc ggattctacg tggtaactca    900

ggtcatcaac gggctggtgc agaccaccgg ctggcccagc gtcgtcacct gcctcggcaa    960

ctggtttgga aaaggaagga gaggtttgat tatgggggtc tggaactccc acacctccgt   1020

gggcaacatc ttggggtcat tgatcgctgg ctactgggtg tccacatgct ggggcctgtc   1080

cttcgtcgtg cctggagcca tcgtggcagc catggggata gtgtgctttc tcttcctcat   1140

tgaacatccg aacgacgtca ggtgctcctc caccctggtg acgcactcaa aaggctatga   1200

gaatggtaca aacagattga gactccagaa gcaaatcttg aagagcgaaa agaacaagcc   1260

tctggaccca gagatgcagt gcctgctgct ctcagatggg aagggctcca tccacccgaa   1320

ccacgtcgtc attctccccg gggacggtgg gagtggcacg gccgccatca gcttcacagg   1380

ggccttgaaa attccaggcg tgatagagtt ctcactgtgt ctgctgtttg ccaagctggt   1440

cagctatact ttcctcttct ggctgcccct gtacatcacg aatgtggatc accttgatgc   1500

caaaaaggcg ggggagctct ccaccctgtt tgacgtgggc ggaatctttg gtgggatcct   1560

ggcaggtgtg atctcagacc gactggagaa aagggcctcc acctgcggcc tgatgctgct   1620

gctcgcggcc cccacgctct acatcttctc caccgtcagc aagatggggc ttgaggccac   1680

catcgccatg ctgctgctca gcggagccct ggtcagtggg ccctacacac tcatcaccac   1740

cgccgtctcc gccgacctgg ggactcataa aagtctgaaa ggcaacgcgc acgccctctc   1800

caccgtgacg gccatcattg acgggacggg ctctgtagga gcagccctgg gccccctgct   1860

ggctgggctc ctctccccgt ccggctggag caatgtgttt tacatgctga tgtttgcaga   1920

tgcctgtgcc ttactgttcc tgatccgcct catacacaag gagctgagct gcccagggtc   1980

agctacgggg gaccaagttc catttaagga acagtgacac cccaccccag tcccgtggag   2040

ggggtctggg cccacccttc acaactgcct ttcaaggaca gttcagacaa agggccctgc   2100

atggaaagag tgacctccct ttgccttttg cacacgcacc tggaaaagac acagaagcca   2160

acctgagaac ccctggtgct attttaaagg agacatattg ctgaacagca gtgagaaaag   2220

tctgcaggaa ctgctgcctg agccaagcca gagaaccgaa gacccggccg gccctggcct   2280

cacaggcgtg tgcccatgca gccacccaaa tgcacgcgtg acaacaaggc cgggagggtg   2340

gggggggtgc acaggtagcc ccgaccctct caggcattcc agccacagaa catcaaagtg   2400

agcgagtact gcgctggctg tggcttcaga gaacctgtat gtgccacatg gaaaaacagg   2460

acaccagagc ccaccagaca gtgccggcca gcagagaagc agagagccag cgccacacaa   2520

catcaagaag gccgacaacc aggttggaaa ccaagacgga gctcagaccc accacatcgc   2580

cccagaggct tttccagcac ccatgatgtt tcggactgac ctaaaaacta attgtcgaga   2640

agccaagggt gaggaggcag gaagcacctc cggttggagg cacccaggct tgccagccac   2700

agagcgcccc aaagtcaccg tcatcccagc ccctggcctt cctgctgccc tccggggcca   2760

tggcactgct gttcagctca ggcacagggg cacagcagag gtttgggaag cggtctcccc   2820

accggcactg ggattggcgg gtccaagccc agcaaccggc ttcgctccac aacacacacc   2880

acacctggga ctgtttttaa tacatagcaa cagactgggt tatttattta agatgtgtat   2940

tgtgtcatat gaagtttaag agacataaat ggcattttgt tatttattaa gacaaactcc   3000

aattgttctc tggctgtttt tttcagttgt gtctagcaaa atacttatct gccctttgaa   3060

ataaaatgtt tttgtttaaa aaatctcaga acactca                            3097


<210>  10270
<211>  533
<212>  PRT
<213>  Homo sapiens

<400>  10270

Met Ala Arg Leu Pro Ala Gly Ile Arg Phe Ile Ile Ser Phe Ser Arg 
1               5                   10                  15


Asp Gln Trp Tyr Arg Ala Phe Ile Phe Ile Leu Thr Phe Leu Leu Tyr 
            20                  25                  30


Ala Ser Phe His Leu Ser Arg Lys Pro Ile Ser Ile Val Lys Gly Glu 
        35                  40                  45


Leu His Lys Tyr Cys Thr Ala Trp Asp Glu Ala Asp Val Arg Phe Ser 
    50                  55                  60


Ser Gln Asn Arg Lys Ser Gly Ser Ala Ala Pro His Gln Leu Pro Asp 
65                  70                  75                  80


Asn Glu Thr Asp Cys Gly Trp Ala Pro Phe Asp Lys Asn Asn Tyr Gln 
                85                  90                  95


Gln Leu Leu Gly Ala Leu Asp Tyr Ser Phe Leu Cys Ala Tyr Ala Val 
            100                 105                 110


Gly Met Tyr Leu Ser Gly Ile Ile Gly Glu Arg Leu Pro Ile Arg Tyr 
        115                 120                 125


Tyr Leu Thr Phe Gly Met Leu Ala Ser Gly Ala Phe Thr Ala Leu Phe 
    130                 135                 140


Gly Leu Gly Tyr Phe Tyr Asn Ile His Ser Phe Gly Phe Tyr Val Val 
145                 150                 155                 160


Thr Gln Val Ile Asn Gly Leu Val Gln Thr Thr Gly Trp Pro Ser Val 
                165                 170                 175


Val Thr Cys Leu Gly Asn Trp Phe Gly Lys Gly Arg Arg Gly Leu Ile 
            180                 185                 190


Met Gly Val Trp Asn Ser His Thr Ser Val Gly Asn Ile Leu Gly Ser 
        195                 200                 205


Leu Ile Ala Gly Tyr Trp Val Ser Thr Cys Trp Gly Leu Ser Phe Val 
    210                 215                 220


Val Pro Gly Ala Ile Val Ala Ala Met Gly Ile Val Cys Phe Leu Phe 
225                 230                 235                 240


Leu Ile Glu His Pro Asn Asp Val Arg Cys Ser Ser Thr Leu Val Thr 
                245                 250                 255


His Ser Lys Gly Tyr Glu Asn Gly Thr Asn Arg Leu Arg Leu Gln Lys 
            260                 265                 270


Gln Ile Leu Lys Ser Glu Lys Asn Lys Pro Leu Asp Pro Glu Met Gln 
        275                 280                 285


Cys Leu Leu Leu Ser Asp Gly Lys Gly Ser Ile His Pro Asn His Val 
    290                 295                 300


Val Ile Leu Pro Gly Asp Gly Gly Ser Gly Thr Ala Ala Ile Ser Phe 
305                 310                 315                 320


Thr Gly Ala Leu Lys Ile Pro Gly Val Ile Glu Phe Ser Leu Cys Leu 
                325                 330                 335


Leu Phe Ala Lys Leu Val Ser Tyr Thr Phe Leu Phe Trp Leu Pro Leu 
            340                 345                 350


Tyr Ile Thr Asn Val Asp His Leu Asp Ala Lys Lys Ala Gly Glu Leu 
        355                 360                 365


Ser Thr Leu Phe Asp Val Gly Gly Ile Phe Gly Gly Ile Leu Ala Gly 
    370                 375                 380


Val Ile Ser Asp Arg Leu Glu Lys Arg Ala Ser Thr Cys Gly Leu Met 
385                 390                 395                 400


Leu Leu Leu Ala Ala Pro Thr Leu Tyr Ile Phe Ser Thr Val Ser Lys 
                405                 410                 415


Met Gly Leu Glu Ala Thr Ile Ala Met Leu Leu Leu Ser Gly Ala Leu 
            420                 425                 430


Val Ser Gly Pro Tyr Thr Leu Ile Thr Thr Ala Val Ser Ala Asp Leu 
        435                 440                 445


Gly Thr His Lys Ser Leu Lys Gly Asn Ala His Ala Leu Ser Thr Val 
    450                 455                 460


Thr Ala Ile Ile Asp Gly Thr Gly Ser Val Gly Ala Ala Leu Gly Pro 
465                 470                 475                 480


Leu Leu Ala Gly Leu Leu Ser Pro Ser Gly Trp Ser Asn Val Phe Tyr 
                485                 490                 495


Met Leu Met Phe Ala Asp Ala Cys Ala Leu Leu Phe Leu Ile Arg Leu 
            500                 505                 510


Ile His Lys Glu Leu Ser Cys Pro Gly Ser Ala Thr Gly Asp Gln Val 
        515                 520                 525


Pro Phe Lys Glu Gln 
    530


<210>  10271
<211>  744
<212>  DNA
<213>  Homo sapiens

<400>  10271
gtgggaagtt cgcgcaagtg cggctctgca gggaggaggg agggccgagg ggaaggccct     60

cgagagagtg gagggcaaca gtggccacgg ttcctctgta cttcgtttct tccctttata    120

gaattgagag attgctgagc ctaaatacat gttgctgcat tgcctccgag aatggccgga    180

cctatcccca ctctcaccaa aacagagtgt gggactcact gctccctcgc ctactgcata    240

aactcaagag gaatttacaa cagatgggct caggcaacaa gttagcccca gagtggagct    300

cagctacaga ggaatgcttc actgaaagaa atcttttcta tggacctctg gttttagaga    360

caacatctag ttctcttaca tcccttgcca cttcccctga tgctgtagga cagacaggtc    420

tgtcccaccc acggtgactc agtcattgtt gttcatggcc gctgcccgtt cttcacgatc    480

aaggaggaga attctttgga ggaaacagag ctttcatacg tgaatcgact gggaagcgag    540

tcaaaagtac tgcaactgga agtgtggcat ggggaggggg ccgtggccag tctcctcact    600

gggctcctgt aggactggga acgcctactc cttcacacct aattatgttt gctggattgg    660

gttatagttc ttcagtgtgt ggactcttgt cagttttata tccgtaggcc gagcacaatg    720

cctggaatac agagcatgct taat                                           744


<210>  10272
<211>  57
<212>  PRT
<213>  Homo sapiens

<400>  10272

Met Gly Ser Gly Asn Lys Leu Ala Pro Glu Trp Ser Ser Ala Thr Glu 
1               5                   10                  15


Glu Cys Phe Thr Glu Arg Asn Leu Phe Tyr Gly Pro Leu Val Leu Glu 
            20                  25                  30


Thr Thr Ser Ser Ser Leu Thr Ser Leu Ala Thr Ser Pro Asp Ala Val 
        35                  40                  45


Gly Gln Thr Gly Leu Ser His Pro Arg 
    50                  55


<210>  10273
<211>  445
<212>  DNA
<213>  Homo sapiens

<400>  10273
aacagtggcc acggttcctc tgtacttcgt ttcttccctt tatagaattg agagattgct     60

gagcctaaat acatgttgct gcattgcctc cgagaatggc cggacctatc cccactctca    120

ccaaaacaga gtgtgggact cactgctccc tcgcctacta tgtaaccttc ctagggatgc    180

tgtttctaac tgctgccggc cccttcttac catctctctg gttgtgcttc tgacgcattc    240

cctacacaac tggaacgtgt ttccaggtca gcctccctaa gcacctccca aggcctccac    300

cccacagtgt cgcacagaac ttgacacata ccagatgctc caattattaa atattactga    360

gtacttttag aaaattggga acatacaata aagtataatg aagaaaataa agaaaaccaa    420

taatctcact tcccaaagat aataa                                          445


<210>  10274
<211>  45
<212>  PRT
<213>  Homo sapiens

<400>  10274

Met Ala Gly Pro Ile Pro Thr Leu Thr Lys Thr Glu Cys Gly Thr His 
1               5                   10                  15


Cys Ser Leu Ala Tyr Tyr Val Thr Phe Leu Gly Met Leu Phe Leu Thr 
            20                  25                  30


Ala Ala Gly Pro Phe Leu Pro Ser Leu Trp Leu Cys Phe 
        35                  40                  45


<210>  10275
<211>  389
<212>  DNA
<213>  Homo sapiens

<400>  10275
cccagagtgg agctcagcta cagaggaatg cttcactgaa agaaatgaca gacaggtctg     60

tcccacccac ggtgactcag tcattgttgt tcatggccgc tgcccgttct tcacgatcaa    120

ggaggagaat tctttggagg aaacagagct ttcatacgtg aatcgactgg gaagcgagtc    180

aaaagtactg caactggaag tgtggcatgg ggagggggcc gtggccagtc tcctcactgg    240

gctcctgtag gactgggaac gcctactcct tcacacctaa ttatgtttgc tggattgggt    300

tatagttctt cagtgtgtgg actcttgtca gttttatatc cgtaggccga gcacaatgcc    360

tggaatacag agcatgctta ataatcaga                                      389


<210>  10276
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  10276

Met Thr Asp Arg Ser Val Pro Pro Thr Val Thr Gln Ser Leu Leu Phe 
1               5                   10                  15


Met Ala Ala Ala Arg Ser Ser Arg Ser Arg Arg Arg Ile Leu Trp Arg 
            20                  25                  30


Lys Gln Ser Phe His Thr 
        35


<210>  10277
<211>  617
<212>  DNA
<213>  Homo sapiens

<400>  10277
ctgggctgcg gagcgcgggc ctcggcggcg cagggcttga cgcgccggaa agtcccctcg     60

ccgctggcca ccagccttcc agcccttacg gcccacgccg taatcctggt gaccgagaag    120

agagcagagc cactgccaga aggaagggga caagacccag caggacacct tctttccacg    180

ctttccagcc tgtgggagcg gcaggggcaa cagagagagg atctggagcc aggattaatg    240

actcatttat gaagcatctt attctgcgac cgaggctcag tggtcagtgg cgacgtaaat    300

ggctcgactc cccgctggca ttcgcttcat catctcattc tccagggatc agtggtacag    360

agccttcatt tttattttga catttctgct gtatgcaagt tttcacttat ctcgaaagcc    420

tatcagcata gttaaggtaa gaatcatgga aagcactgcc tgtcgtctct gtgaggagtt    480

cgtcacttga aaagcttgtg gggcagagga tggggatggt agcaggtaca tggggaaaca    540

gattatgtag aaacaagtta ttctgctgct ttggcttttc ggtttccctt tgctaaaatt    600

aaagtctttt aaatgtt                                                   617


<210>  10278
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  10278

Met Ala Arg Leu Pro Ala Gly Ile Arg Phe Ile Ile Ser Phe Ser Arg 
1               5                   10                  15


Asp Gln Trp Tyr Arg Ala Phe Ile Phe Ile Leu Thr Phe Leu Leu Tyr 
            20                  25                  30


Ala Ser Phe His Leu Ser Arg Lys Pro Ile Ser Ile Val Lys Val Arg 
        35                  40                  45


Ile Met Glu Ser Thr Ala Cys Arg Leu Cys Glu Glu Phe Val Thr 
    50                  55                  60


<210>  10279
<211>  3664
<212>  DNA
<213>  Homo sapiens

<400>  10279
cggcggcgca ggtgaggcgc ggggccgggg ccggaccggg aggcggggac cccccgcccc     60

cccgcccgca cctgcggggc agccggcgct caggcgccgc agccgctcag cacctgcggc    120

gccctcaggg agccgggcgc ggggccctgc gcactcggag ctcggctcct ctccttcctt    180

ttcttttttt tcggggggag gtgggggctg gtttggatgt tttccgagag ccggggacgg    240

tctcaagcta ttttcgcgga gggaagtctt tgaaatacga catctagaag agtggccctc    300

ggcgacaatg ccgggcgttc ccggaccggg gcaacgctgg gattccgggg aagtggaggc    360

agagggagcg ggcacggggc cggcagccgc tccacggagt ccccggcagg ggcgagctta    420

gctgtccagc cgggtcccct gcccaccccg gcccgggccg cggtgacagc tgagggtcca    480

gagagccggc aggaggggac cctgcgcatt gtctgccgcg atggggacgt gggcgtgccc    540

gcggaattca cctcctccgg ggaccagccg cccagggagg agccggcaca gaacgctggc    600

tcggagcgcc ggcaccctgg gcctttgcgt tgtttgtcgg ctgagcagct ggttcccgga    660

gcccgtgggc ctcctggcca atgcgagtga cagcgacctt ctgggtttat aataaagggc    720

ttgacgcgcc ggaaagtccc ctcgccgctg gccaccagcc ttccagccct tacggcccac    780

gccgtaatcc tggtgaccga gaagagagca gagccactgc cagaaggaag gggacaagac    840

ccagcaggac accttctttc cacgctttcc agcctgtggg agcggcaggg gcaacagaga    900

gaggatctgg agccaggatt aatgactcat ttatgaagca tcttattctg cgaccgaggc    960

tcagtggtca gtggcgacgt aaatggctcg actccccgct ggcattcgct tcatcatctc   1020

attctccagg gatcagtggt acagagcctt catttttatt ttgacatttc tgctgtatgc   1080

aagttttcac ttatctcgaa agcctatcag catagttaag ggtgagctcc acaagtactg   1140

cactgcttgg gatgaagctg acgtcaggtt cagcagccag aacaggaagt ctgggtccgc   1200

tgccccccac cagctccctg acaatgagac cgactgtggc tgggcaccgt ttgataagaa   1260

caactatcag cagctgcttg gggccctgga ctactccttc ctgtgcgcct atgccgtggg   1320

gatgtacctc agtggcatca ttggggagcg cctgccgatt aggtattacc taactttcgg   1380

gatgctcgcc agcggagcct tcaccgccct gttcggctta gggtatttct acaacatcca   1440

cagtttcgga ttctacgtgg taactcaggt catcaacggg ctggtgcaga ccaccggctg   1500

gcccagcgtc gtcacctgcc tcggcaactg gtttggaaaa ggaaggagag gtttgattat   1560

gggggtctgg aactcccaca cctccgtggg caacatcttg gggtcattga tcgctggcta   1620

ctgggtgtcc acatgctggg gcctgtcctt cgtcgtgcct ggagccatcg tggcagccat   1680

ggggatagtg tgctttctct tcctcattga acatccgaac gacgtcaggt gctcctccac   1740

cctggtgacg cactcaaaag gctatgagaa tggtacaaac agattgagac tccagaagca   1800

aatcttgaag agcgaaaaga acaagcctct ggacccagag atgcagtgcc tgctgctctc   1860

agatgggaag ggctccatcc acccgaacca cgtcgtcatt ctccccgggg acggtgggag   1920

tggcacggcc gccatcagct tcacaggggc cttgaaaatt ccaggcgtga tagagttctc   1980

actgtgtctg ctgtttgcca agctggtcag ctatactttc ctcttctggc tgcccctgta   2040

catcacgaat gtggatcacc ttgatgccaa aaaggcgggg gagctctcca ccctgtttga   2100

cgtgggcgga atctttggtg ggatcctggc aggtgtgatc tcagaccgac tggagaaaag   2160

ggcctccacc tgcggcctga tgctgctgct cgcggccccc acgctctaca tcttctccac   2220

cgtcagcaag atggggcttg aggccaccat cgccatgctg ctgctcagcg gagccctggt   2280

cagtgggccc tacacactca tcaccaccgc cgtctccgcc gacctgggga ctcataaaag   2340

tctgaaaggc aacgcgcacg ccctctccac cgtgacggcc atcattgacg ggacgggctc   2400

tgtaggagca gccctgggcc ccctgctggc tgggctcctc tccccgtccg gctggagcaa   2460

tgtgttttac atgctgatgt ttgcagatgc ctgtgcctta ctgttcctga tccgcctcat   2520

acacaaggag ctgagctgcc cagggtcagc tacgggggac caagttccat ttaaggaaca   2580

gtgacacccc accccagtcc cgtggagggg gtctgggccc acccttcaca actgcctttc   2640

aaggacagtt cagacaaagg gccctgcatg gaaagagtga cctccctttg ccttttgcac   2700

acgcacctgg aaaagacaca gaagccaacc tgagaacccc tggtgctatt ttaaaggaga   2760

catattgctg aacagcagtg agaaaagtct gcaggaactg ctgcctgagc caagccagag   2820

aaccgaagac ccggccggcc ctggcctcac aggcgtgtgc ccatgcagcc acccaaatgc   2880

acgcgtgaca acaaggccgg gagggtgggg ggggtgcaca ggtagccccg accctctcag   2940

gcattccagc cacagaacat caaagtgagc gagtactgcg ctggctgtgg cttcagagaa   3000

cctgtatgtg ccacatggaa aaacaggaca ccagagccca ccagacagtg ccggccagca   3060

gagaagcaga gagccagcgc cacacaacat caagaaggcc gacaaccagg ttggaaacca   3120

agacggagct cagacccacc acatcgcccc agaggctttt ccagcaccca tgatgtttcg   3180

gactgaccta aaaactaatt gtcgagaagc caagggtgag gaggcaggaa gcacctccgg   3240

ttggaggcac ccaggcttgc cagccacaga gcgccccaaa gtcaccgtca tcccagcccc   3300

tggccttcct gctgccctcc ggggccatgg cactgctgtt cagctcaggc acaggggcac   3360

agcagaggtt tgggaagcgg tctccccacc ggcactggga ttggcgggtc caagcccagc   3420

aaccggcttc gctccacaac acacaccaca cctgggactg tttttaatac atagcaacag   3480

actgggttat ttatttaaga tgtgtattgt gtcatatgaa gtttaagaga cataaatggc   3540

attttgttat ttattaagac aaactccaat tgttctctgg ctgttttttt cagttgtgtc   3600

tagcaaaata cttatctgcc ctttgaaata aaatgttttt gtttaaaaaa tctcagaaca   3660

ctca                                                                3664


<210>  10280
<211>  533
<212>  PRT
<213>  Homo sapiens

<400>  10280

Met Ala Arg Leu Pro Ala Gly Ile Arg Phe Ile Ile Ser Phe Ser Arg 
1               5                   10                  15


Asp Gln Trp Tyr Arg Ala Phe Ile Phe Ile Leu Thr Phe Leu Leu Tyr 
            20                  25                  30


Ala Ser Phe His Leu Ser Arg Lys Pro Ile Ser Ile Val Lys Gly Glu 
        35                  40                  45


Leu His Lys Tyr Cys Thr Ala Trp Asp Glu Ala Asp Val Arg Phe Ser 
    50                  55                  60


Ser Gln Asn Arg Lys Ser Gly Ser Ala Ala Pro His Gln Leu Pro Asp 
65                  70                  75                  80


Asn Glu Thr Asp Cys Gly Trp Ala Pro Phe Asp Lys Asn Asn Tyr Gln 
                85                  90                  95


Gln Leu Leu Gly Ala Leu Asp Tyr Ser Phe Leu Cys Ala Tyr Ala Val 
            100                 105                 110


Gly Met Tyr Leu Ser Gly Ile Ile Gly Glu Arg Leu Pro Ile Arg Tyr 
        115                 120                 125


Tyr Leu Thr Phe Gly Met Leu Ala Ser Gly Ala Phe Thr Ala Leu Phe 
    130                 135                 140


Gly Leu Gly Tyr Phe Tyr Asn Ile His Ser Phe Gly Phe Tyr Val Val 
145                 150                 155                 160


Thr Gln Val Ile Asn Gly Leu Val Gln Thr Thr Gly Trp Pro Ser Val 
                165                 170                 175


Val Thr Cys Leu Gly Asn Trp Phe Gly Lys Gly Arg Arg Gly Leu Ile 
            180                 185                 190


Met Gly Val Trp Asn Ser His Thr Ser Val Gly Asn Ile Leu Gly Ser 
        195                 200                 205


Leu Ile Ala Gly Tyr Trp Val Ser Thr Cys Trp Gly Leu Ser Phe Val 
    210                 215                 220


Val Pro Gly Ala Ile Val Ala Ala Met Gly Ile Val Cys Phe Leu Phe 
225                 230                 235                 240


Leu Ile Glu His Pro Asn Asp Val Arg Cys Ser Ser Thr Leu Val Thr 
                245                 250                 255


His Ser Lys Gly Tyr Glu Asn Gly Thr Asn Arg Leu Arg Leu Gln Lys 
            260                 265                 270


Gln Ile Leu Lys Ser Glu Lys Asn Lys Pro Leu Asp Pro Glu Met Gln 
        275                 280                 285


Cys Leu Leu Leu Ser Asp Gly Lys Gly Ser Ile His Pro Asn His Val 
    290                 295                 300


Val Ile Leu Pro Gly Asp Gly Gly Ser Gly Thr Ala Ala Ile Ser Phe 
305                 310                 315                 320


Thr Gly Ala Leu Lys Ile Pro Gly Val Ile Glu Phe Ser Leu Cys Leu 
                325                 330                 335


Leu Phe Ala Lys Leu Val Ser Tyr Thr Phe Leu Phe Trp Leu Pro Leu 
            340                 345                 350


Tyr Ile Thr Asn Val Asp His Leu Asp Ala Lys Lys Ala Gly Glu Leu 
        355                 360                 365


Ser Thr Leu Phe Asp Val Gly Gly Ile Phe Gly Gly Ile Leu Ala Gly 
    370                 375                 380


Val Ile Ser Asp Arg Leu Glu Lys Arg Ala Ser Thr Cys Gly Leu Met 
385                 390                 395                 400


Leu Leu Leu Ala Ala Pro Thr Leu Tyr Ile Phe Ser Thr Val Ser Lys 
                405                 410                 415


Met Gly Leu Glu Ala Thr Ile Ala Met Leu Leu Leu Ser Gly Ala Leu 
            420                 425                 430


Val Ser Gly Pro Tyr Thr Leu Ile Thr Thr Ala Val Ser Ala Asp Leu 
        435                 440                 445


Gly Thr His Lys Ser Leu Lys Gly Asn Ala His Ala Leu Ser Thr Val 
    450                 455                 460


Thr Ala Ile Ile Asp Gly Thr Gly Ser Val Gly Ala Ala Leu Gly Pro 
465                 470                 475                 480


Leu Leu Ala Gly Leu Leu Ser Pro Ser Gly Trp Ser Asn Val Phe Tyr 
                485                 490                 495


Met Leu Met Phe Ala Asp Ala Cys Ala Leu Leu Phe Leu Ile Arg Leu 
            500                 505                 510


Ile His Lys Glu Leu Ser Cys Pro Gly Ser Ala Thr Gly Asp Gln Val 
        515                 520                 525


Pro Phe Lys Glu Gln 
    530


<210>  10281
<211>  1002
<212>  DNA
<213>  Homo sapiens

<400>  10281
ttcgcggagg gaagtctttg aaatacgaca tctagaagag tggccctcgg cgacaatgcc     60

gggcgttccc ggaccggggc aacgctggga ttccggggaa gtggaggcag agggagcggg    120

cacggggccg gcagccgctc cacggagtcc ccggcagggg cgagcttagc tgtccagccg    180

ggtcccctgc ccaccccggc ccgggccgcg gtgacagctg agggtccaga gagccggcag    240

gaggggaccc tgcgcattgt ctgccgcgat ggggacgtgg gcgtgcccgc ggaattcacc    300

tcctccgggg accagccgcc cagggaggag ccggcacaga acgctggctc ggagcgccgg    360

caccctgggc ctttgcgttg tttgtcggct gagcagctgg ttcccggagc ccgtgggcct    420

cctggccaat gcgagtgaca gcgaccttct gggtttataa taaagggctt gacgcgccgg    480

aaagtcccct cgccgctggc caccagcctt ccagccctta cggcccacgc cgtaatcctg    540

gtgaccgaga agagagcaga gccactgcca gaaggaaggg gacaagaccc agcaggacac    600

cttctttcca cgctttccag cctggtggga gtggcacggc cgccatcagc ttcacagggg    660

ccttgaaaat tccaggcgtg atagagttct cactgtgtct gctgtttgcc aagctggtca    720

gctatacttt cctcttctgg ctgcccctgt acatcacgaa tgtggatcac cttgatgcca    780

aaaaggcggg ggagctctcc accctgtttg acgtgggcgg aatctttggt gggatcctgg    840

caggtgtgat ctcagaccga ctggagaaaa gggcctccac ctgcggcctg atgctgctgc    900

tcgcggcccc cacggtcagc cgtgctgcct tccctgggcc ccaaagcctg cagacagtcc    960

cccactgtcc tcctcgccag ccagcatcct tccatctggc cc                      1002


<210>  10282
<211>  190
<212>  PRT
<213>  Homo sapiens

<400>  10282

Met Arg Val Thr Ala Thr Phe Trp Val Tyr Asn Lys Gly Leu Asp Ala 
1               5                   10                  15


Pro Glu Ser Pro Leu Ala Ala Gly His Gln Pro Ser Ser Pro Tyr Gly 
            20                  25                  30


Pro Arg Arg Asn Pro Gly Asp Arg Glu Glu Ser Arg Ala Thr Ala Arg 
        35                  40                  45


Arg Lys Gly Thr Arg Pro Ser Arg Thr Pro Ser Phe His Ala Phe Gln 
    50                  55                  60


Pro Gly Gly Ser Gly Thr Ala Ala Ile Ser Phe Thr Gly Ala Leu Lys 
65                  70                  75                  80


Ile Pro Gly Val Ile Glu Phe Ser Leu Cys Leu Leu Phe Ala Lys Leu 
                85                  90                  95


Val Ser Tyr Thr Phe Leu Phe Trp Leu Pro Leu Tyr Ile Thr Asn Val 
            100                 105                 110


Asp His Leu Asp Ala Lys Lys Ala Gly Glu Leu Ser Thr Leu Phe Asp 
        115                 120                 125


Val Gly Gly Ile Phe Gly Gly Ile Leu Ala Gly Val Ile Ser Asp Arg 
    130                 135                 140


Leu Glu Lys Arg Ala Ser Thr Cys Gly Leu Met Leu Leu Leu Ala Ala 
145                 150                 155                 160


Pro Thr Val Ser Arg Ala Ala Phe Pro Gly Pro Gln Ser Leu Gln Thr 
                165                 170                 175


Val Pro His Cys Pro Pro Arg Gln Pro Ala Ser Phe His Leu 
            180                 185                 190


<210>  10283
<211>  3153
<212>  DNA
<213>  Homo sapiens

<400>  10283
tatgccacca gaagacgagc ctcgggagca gttttagttc taagagctcc aagctgaaag     60

ccgactgcct gtcatccttg accacctgtc cacaaggaag aaggggtaca ttttcctaga    120

ttcacacaac tgaatgctac acacccgtga aaaagaacaa gttacaggtc caggcaacaa    180

tgaggatgaa cctcacaaac ataacatgaa gcagaaggag gcagacatga aagagtacag    240

actgcagcat tccactcata ggaagtccaa gcatgggcaa cgaatccatg cggctagaga    300

tggagtttca ctttgtcgcc caggctggag ggcaatggtg cgctctcggc tcactgcaaa    360

cttcgcctcc cggattcaag ctattctcct gcctcagcct ccccagtagc tgggattaca    420

ggcgcctgtc accatgcctg gttaattttt tttgtatttt tagtatagat agggtttcac    480

tatgttggcc agtttggtct tgaactcctg acctcaggtg atccgcccac ctcggcctcc    540

caaagtgctg ggattacagg cgtgagccac tgcgcctagc cagttttctc cttttaagtc    600

ctgtgtgtcc agagaggggt gggcacactc acattcaaat caatgctgcc atccccctgg    660

ctccagggac ccctgcagtt taagcttctc cgggaagcct ctgctttcag gtttcttttc    720

tggcccagtc caggtgaaaa gagctcgcac taagatctct gctgggagtc agactcacct    780

gtctaccagc ttgggcagac gcttgccttg agtcctgagg ctaggccaca gctggagcag    840

cagatagaag ggacagggtt gcacttataa caccactatc ctcccagccc tggttttatc    900

atcatcatcg agaaaaatac aattaatcag cagtgatcaa aggtaagtct aaacattcca    960

tttaactaac ttaaatgtga cctggtgtgc cgtgtcattc tataaatgac ataacagaat   1020

aagactcact ttctaattca cagcctctgg ttcaatttca agtaagcaaa tacattttgc   1080

tttggttttg cttacaatat tctgggaaat gcaggctata aataatcact caactgtttt   1140

gtgggtcaac agaatcacta ctactttcag tttcgttgat gccatttata tcatgagctc   1200

aagcacacgg gcgcttcaga aggcactata aagtttagtt ttgatgtggt gtgatgttct   1260

gatctatctt gaaaggtaaa gaaacccaca ggattcagcg tcaagccaat ccatgcccag   1320

gcacatcgca gctgctaggt caggaaatct gtgcgtttag gaggctctga gggtgatgct   1380

gggactgtac tcaggtaatt aaacccggac aaaccctgag gcacagagag gatgagtagg   1440

ggccctggag gcagcctgac ccacagggaa ttctcgagtg tgtggcagcc ctgcctgggg   1500

aacgaagacc cgagcctcaa tttcctcaca ggggcactcg cagggttgct gtgaggatca   1560

caggggtaat gtatgtggca gtttgtcata ccccagggct ctgtaagcgg cagttattta   1620

tattgttact tatgacactg aactaagagc tgaccctgac gccgcctcct cagaagccct   1680

aagtcttgag tggcctggac accactacac acgagagtca ggggcggggg ctttgagatg   1740

gaccaccagg aaagccggga gagggaccgg gacagggctc ccacttgctc ctggctcaca   1800

ggggccctca tagtcatcag gtggacccca acagctgtgg cctgacaaag attcccccaa   1860

aggccagccc accttacacg ctacatctgc cccaacagcc ccccagccca acaggtggtg   1920

ccttcatgga gatgcccatc cctgcacgta gcactcaagg cagttctccc acctgtaaag   1980

ctgtttttct tcccctacaa tccacaccca acctttctag gtcaatcctg aaaccccaca   2040

caagctcccc aactacacca gatccttcaa ctccaacacg ctcaccaagt ctcttcaata   2100

gtcacttcca tctttataat ttaccatttt cttgagctgt ttgtatattt ctctaaccag   2160

aaagacaaga agtagtagta ttcagattta taatgactgg ttactggtac tgatttgaga   2220

gtttcttgtc aagcggatga gtgtttaagg cccaccacct cttttcatat tcttctctct   2280

taaaaaccac attttcaaag gtctgcaaac gttttccaca gtcaacaact tgagaggcat   2340

ggaagtttct tgcttatcag gggccaaggg ggaattttag aatcttttgg gtaaatgaat   2400

gtttaacatc ccctgaaagc tgctggagag tggggaacct aggaccgtca caaaacagcc   2460

agcctctgca ttgcctctgc cgaccagggc tgcagagggc agccacccag ggctcagcca   2520

ccggcaggag tggaggaagc acagctccaa aggtcacaga attgcagtcc tggagctggg   2580

tccctgccaa ctcccggaga gtgagcgagg ggccactggg ctgtgaatgc actgtctctg   2640

gcagtggatg atttcctcgt tcttctacga tagagactct aatgcctctc aggcccctga   2700

tggtctacag gccgggtgac gtaatcccaa tgagggtaag aaaattattc ctgcttttct   2760

ccaggttata actggtgatt atgtaggctt gtctgcttta atcttctttt ctcaaagtct   2820

agtagaacac ctgcttaaca acttcctgcc cacccatcac tcagacaaaa atgcagcctt   2880

tccatgattc ttaccttaac tatgctgata ggctttcgag ataagtgaaa acttgcatac   2940

agcagaaatg tcaaaataaa aatgaaggct ctgtacctga aacacaaaac agtgggagag   3000

gatgatatga aataacagaa gttatgttag gaatacatat cactgtgttc tgaaacgttc   3060

ttatgctgtg tattattcat tcagttctac agccattatc aatattactt atgtcactat   3120

aatattggaa cattaaaaaa tattgccacg ttt                                3153


<210>  10284
<211>  91
<212>  PRT
<213>  Homo sapiens

<400>  10284

Met Leu His Thr Arg Glu Lys Glu Gln Val Thr Gly Pro Gly Asn Asn 
1               5                   10                  15


Glu Asp Glu Pro His Lys His Asn Met Lys Gln Lys Glu Ala Asp Met 
            20                  25                  30


Lys Glu Tyr Arg Leu Gln His Ser Thr His Arg Lys Ser Lys His Gly 
        35                  40                  45


Gln Arg Ile His Ala Ala Arg Asp Gly Val Ser Leu Cys Arg Pro Gly 
    50                  55                  60


Trp Arg Ala Met Val Arg Ser Arg Leu Thr Ala Asn Phe Ala Ser Arg 
65                  70                  75                  80


Ile Gln Ala Ile Leu Leu Pro Gln Pro Pro Gln 
                85                  90


<210>  10285
<211>  642
<212>  DNA
<213>  Homo sapiens

<400>  10285
agaaaaccgc caggagtcac agcgcgacga gtgtgcgggg aaggcggcgg ggccgggagt     60

cacagcgcga cgagtgtgcg gggaaggcgg tggggctggg agctggcaat gtcttctgtc    120

tacagactcc ctcgccacat ccagccctcc ccacccctcc cactggcagc gagaggaaat    180

cccgtccggg gagcagcagg cagctgcggt gggaatttca tgacactaga aaagactgga    240

ctcctccctc atcctacacc tgcagagccc cacgcagtca tttaggcaca aacattcact    300

gtattcgcct gcattccatg aaggctccgt tctttccatg ctgaatttga gccacttcgc    360

agacagaagt ggccctgggt tctcagcccc acctaagttg cctaagacta cagccacgcg    420

acacattctc tgcagcagat ggagtttcac tttgtcgccc aggctggagg gcaatggtgc    480

gctctcggct cactgcaaac ttcgcctccc ggattcaagc tattctcctg cctcagcctc    540

cccagtagct gggattacag gcgcctgtca ccatgcctgg ttaatttttt ttgtattttt    600

agtatagata gggtttcact atgttggcca gtttggtctt ga                       642


<210>  10286
<211>  89
<212>  PRT
<213>  Homo sapiens

<400>  10286

Met Leu Asn Leu Ser His Phe Ala Asp Arg Ser Gly Pro Gly Phe Ser 
1               5                   10                  15


Ala Pro Pro Lys Leu Pro Lys Thr Thr Ala Thr Arg His Ile Leu Cys 
            20                  25                  30


Ser Arg Trp Ser Phe Thr Leu Ser Pro Arg Leu Glu Gly Asn Gly Ala 
        35                  40                  45


Leu Ser Ala His Cys Lys Leu Arg Leu Pro Asp Ser Ser Tyr Ser Pro 
    50                  55                  60


Ala Ser Ala Ser Pro Val Ala Gly Ile Thr Gly Ala Cys His His Ala 
65                  70                  75                  80


Trp Leu Ile Phe Phe Val Phe Leu Val 
                85


<210>  10287
<211>  591
<212>  DNA
<213>  Homo sapiens

<400>  10287
tccagacacg tactggggag ggtgctgcac cgctgtgtgg tgtagtgagg acgcgggaac     60

agtggagcgc tcaccccgag caggggcacc agggaggggc ggggcctctg agaagggtgg    120

ggccccagct gcagctcctc ggccactgtc acatggggtg caggcccagc gtggccagat    180

tttctacttt tcaagtgaag acaggaagcc ctgtttatct acggcgtttc tgaatttcga    240

aatggagttc aggatcaaaa cccagtgtct ttacatcaga gtcgagtcaa tgcaaacatg    300

gacgggtttg attttcatac tacatcgcct ggaaaactta gctattaaaa gagttctcgt    360

atagccgggt gcagtggact gagtatcgaa tggctccttc ttcttccctg gaactgaaat    420

cattgtacat tatcaagcca cctggaaaca cacagatgaa acaattccga ccattgtgtc    480

agcacacagg cgtacaggct accgcatccc gccttgttgt gtcaacaagc gagagctgtg    540

tctgctccct ggtgctgtgg ctgtcagtgc tggagagcac ggcctggaca g             591


<210>  10288
<211>  66
<212>  PRT
<213>  Homo sapiens

<400>  10288

Met Ala Pro Ser Ser Ser Leu Glu Leu Lys Ser Leu Tyr Ile Ile Lys 
1               5                   10                  15


Pro Pro Gly Asn Thr Gln Met Lys Gln Phe Arg Pro Leu Cys Gln His 
            20                  25                  30


Thr Gly Val Gln Ala Thr Ala Ser Arg Leu Val Val Ser Thr Ser Glu 
        35                  40                  45


Ser Cys Val Cys Ser Leu Val Leu Trp Leu Ser Val Leu Glu Ser Thr 
    50                  55                  60


Ala Trp 
65


<210>  10289
<211>  1410
<212>  DNA
<213>  Homo sapiens

<400>  10289
tgagaagcgg cgggcagggt ggccgttgcc atgtcatgcg acacacggcc tggttctgag     60

aagtggtggg cagggtggct gttgccattt gtcatgcgac acacggcctg gttctgagaa    120

gtggtgggca gggtggctgt tgctcagaaa gccacacttt ggcttttgct gttcaccaaa    180

gtgagaccag accagcctcg tctctgccct tcatgttggt tccttccttt cactggatcc    240

agaggggctt tgagtgtatt gggtggcggc agtagtcacc cctctgatct tctgtcttgg    300

gcatctcagt aggaagtcgg gggactgcgg ggctgagctc agttctggtt gacgttgtga    360

ctgcgtggcc ttctcttggc cttgtgcctc agtggactgc agtctgcaat tcggtctgac    420

tctgctgtga aaccctgttc ttaaagctaa cttggcgctc tactggcaac cccgattgct    480

gttttaaaag cagaggatca gcataaaaaa agagaaggaa atcatgaact aggtgaaaaa    540

acacattttt cttcatattc tcaaaatgag agggaagcag aagtctgtgg ctaagggtgg    600

agaccctgcg tctgtgaaca gaggccactg cccaccactg cccccaagca ggtggaggga    660

ggcacagttc tgaatgcctt tggcccctca caaggaaggt ggcacacaca ccggaccccc    720

tctggccttc tgttaacctg caccaagtcc tgactgtccg cggagctgcc gcgcccacct    780

tgatggctgc tgcgttacac cagaggcagg accaggacct gactcctcca ggctccactg    840

cccatcagtg cctgctgcct gctcagtgaa tggtcaccat ggaaacggcg ctcaggccta    900

cccaccccca ccaccacgcc ttggtcattg ttccttccat gagtgagtgc tgcccagcaa    960

gacaaagtac aggctccagt gggaaggcca ccatgtcagc caagtccctt cccgaaggag   1020

gtgcccgcat gcttattcag tgtcactgtc cactccttgg cagtgactcg ggtggaggcg   1080

aaacatgact aatcgtaaat cacccctgcc ttctcccaag tgccacacgg tttgttgaca   1140

cggtgtgcgc ctggggcgtt cacagtgctt agaatcgcag aggttgccgt ttctgtacat   1200

ttcatgcaga gcaattaaat agggcactgc atttttcttc aagttaattt ttatttatta   1260

aagtaaaaca taatgtacct tagaagctag acagtcctac aagcttatta tgttgtacag   1320

cggcgttccg tccccctccc cagccctctc tttctagagg cagccaattt cagctgcctc   1380

tctctgctta cctacgtatt tccatgtttc                                    1410


<210>  10290
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  10290

Met Val Thr Met Glu Thr Ala Leu Arg Pro Thr His Pro His His His 
1               5                   10                  15


Ala Leu Val Ile Val Pro Ser Met Ser Glu Cys Cys Pro Ala Arg Gln 
            20                  25                  30


Ser Thr Gly Ser Ser Gly Lys Ala Thr Met Ser Ala Lys Ser Leu Pro 
        35                  40                  45


Glu Gly Gly Ala Arg Met Leu Ile Gln Cys His Cys Pro Leu Leu Gly 
    50                  55                  60


Ser Asp Ser Gly Gly Gly Glu Thr 
65                  70


<210>  10291
<211>  657
<212>  DNA
<213>  Homo sapiens

<400>  10291
atacacatgt aggatggcct gttttggtag atgcatggga aaaagcatga agaatttcca     60

ccaacctatg aactgacata ttcaactctg agagaacttc caggtaaaca tggtcggcta    120

ctcatgtgtt atctccacac ccccaagcaa catgaactgc gccatcactg acttctaaag    180

atgataaatc ctcccaccga agggcacgta gttttggaag atggacacag aagggctgac    240

agctaacaca gcctccagtg ttccctgctc cactgagcat cctcagaggg agacagcaca    300

gggacacctg gagcagagcg aggcccagcg gagcccaaga gacaggggag gggaaggcaa    360

ggaaggagga acgcagtggg aacggaaggg ggtcagcaag agaaaaaagg tgcatgggtt    420

gagtctttta tcacaaactg ttagctacat tccctctgcc gcacctcgga tcccaggtct    480

cttttctcat cctcactgat aaagagactc ctcctgatgc ccccgtgcag gacagcgcag    540

cttaacccgt ggggacacta agcccagtgc aggacaggga tgctcaccta acaggcgaca    600

ggggatctgg ggaaagacac cagcttccac caagcttcca tgccatggca aggatgt       657


<210>  10292
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  10292

Met His Gly Lys Lys His Glu Glu Phe Pro Pro Thr Tyr Glu Leu Thr 
1               5                   10                  15


Tyr Ser Thr Leu Arg Glu Leu Pro Gly Lys His Gly Arg Leu Leu Met 
            20                  25                  30


Cys Tyr Leu His Thr Pro Lys Gln His Glu Leu Arg His His 
        35                  40                  45


<210>  10293
<211>  901
<212>  DNA
<213>  Homo sapiens

<400>  10293
gggtctgggc ccacccttca caactgcctt tcaaggacag ttcagacaaa gggccctgca     60

tggaaagagt gacctccctt tgccttttgc acacgcacct ggaaaagaca cagaagccaa    120

cctgagaacc cctggtgcta ttttaaagga gacatattgc tgaacagcag tgagaaaagt    180

ctgcaggaac tgctgcctga gccaagccag agaaccgaag acccggccgg ccctggcctc    240

acaggcgtgt gcccatgcag ccacccaaat gcacgcgtga caacaaggcc gggagggtgg    300

ggggggtgca caggtagccc cgaccctctc aggcattcca gccacagaac atcaaagtga    360

gcgagtactg cgctggctgt ggcttcagag aacctgtatg tgccacatgg aaaaacagga    420

caccagagcc caccagacag tgccggccag cagagaagca gagagccagc gccacacaac    480

atcaagaagg ccgacaacca ggttggaaac caagacggag ctcagaccca ccacatcgcc    540

ccagaggctt ttccagcacc catgatgttt cggactgacc taaaaactaa ttgtcgagaa    600

gccaagggtg aggaggcagg aacggtctcc ccaccggcac tgggattggc gggtccaagc    660

ccagcaaccg gcttcgctcc acaacacaca ccacacctgg gactgttttt aatacatagc    720

aacagactgg gttatttatt taagatgtgt attgtgtcat atgaagttta agagacataa    780

atggcatttt gttatttatt aagacaaact ccaattgttc tctggctgtt tttttcagtt    840

gtgtctagca aaatacttat ctgccctttg aaataaaatg tttttgttta aaaaatctca    900

g                                                                    901


<210>  10294
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  10294

Met Met Phe Arg Thr Asp Leu Lys Thr Asn Cys Arg Glu Ala Lys Gly 
1               5                   10                  15


Glu Glu Ala Gly Thr Val Ser Pro Pro Ala Leu Gly Leu Ala Gly Pro 
            20                  25                  30


Ser Pro Ala Thr Gly Phe Ala Pro Gln His Thr Pro His Leu Gly Leu 
        35                  40                  45


Phe Leu Ile His Ser Asn Arg Leu Gly Tyr Leu Phe Lys Met Cys Ile 
    50                  55                  60


Val Ser Tyr Glu Val 
65


<210>  10295
<211>  894
<212>  DNA
<213>  Homo sapiens

<400>  10295
gggtctgggc ccacccttca caactgcctt tcaaggacag ttcagacaaa gggccctgca     60

tggaaagagt gacctccctt tgccttttgc acacgcacct ggaaaagaca cagaagccaa    120

cctgagaacc cctggtgcta ttttaaagga gacatattgc tgaacagcag tgagaaaagt    180

ctgcaggaac tgctgcctga gccaagccag agaaccgaag acccggccgg ccctggcctc    240

acaggcgtgt gcccatgcag ccacccaaat gcacgcgtga caacaaggcc gggagggtgg    300

ggggggtgca caggtagccc cgaccctctc aggcattcca gccacagaac atcaaagtga    360

gcgagtactg cgctggctgt ggcttcagag aacctgtatg tgccacatgg aaaaacagga    420

caccagagcc caccagacag tgccggccag cagagaagca gagagccagc gccacacaac    480

atcaagaagg cttgccagcc acagagcgcc ccaaagtcac cgtcatccca gcccctggcc    540

ttcctgctgc cctccggggc catggcactg ctgttcagct caggcacagg ggcacagcag    600

aggtttggga agcggtctcc ccaccggcac tgggattggc gggtccaagc ccagcaaccg    660

gcttcgctcc acaacacaca ccacacctgg gactgttttt aatacatagc aacagactgg    720

gttatttatt taagatgtgt attgtgtcat atgaagttta agagacataa atggcatttt    780

gttatttatt aagacaaact ccaattgttc tctggctgtt tttttcagtt gtgtctagca    840

aaatacttat ctgccctttg aaataaaatg tttttgttta aaaaatctca gaac          894


<210>  10296
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  10296

Met Cys His Met Glu Lys Gln Asp Thr Arg Ala His Gln Thr Val Pro 
1               5                   10                  15


Ala Ser Arg Glu Ala Glu Ser Gln Arg His Thr Thr Ser Arg Arg Leu 
            20                  25                  30


Ala Ser His Arg Ala Pro Gln Ser His Arg His Pro Ser Pro Trp Pro 
        35                  40                  45


Ser Cys Cys Pro Pro Gly Pro Trp His Cys Cys Ser Ala Gln Ala Gln 
    50                  55                  60


Gly His Ser Arg Gly Leu Gly Ser Gly Leu Pro Thr Gly Thr Gly Ile 
65                  70                  75                  80


Gly Gly Ser Lys Pro Ser Asn Arg Leu Arg Ser Thr Thr His Thr Thr 
                85                  90                  95


Pro Gly Thr Val Phe Asn Thr 
            100


<210>  10297
<211>  831
<212>  DNA
<213>  Homo sapiens

<400>  10297
gggtctgggc ccacccttca caactgcctt tcaaggacag ttcagacaaa gggccctgca     60

tggaaagagt gacctccctt tgccttttgc acacgcacct ggaaaagaca cagaagccaa    120

cctgagaacc cctggtgcta ttttaaagga gacatattgc tgaacagcag tgagaaaagt    180

ctgcaggaac tgctgcctga gccaagccag agaaccgaag acccggccgg ccctggcctc    240

acaggcgtgt gcccatgcag ccacccaaat gcacgcgtga caacaaggcc gggagggtgg    300

ggggggtgca caggtagccc cgaccctctc aggcattcca gccacagaac atcaaagtga    360

gcgagtactg cgctggctgt ggcttcagag aacctgtatg tgccacatgg aaaaacagga    420

caccagagcc caccagacag tgccggccag cagagaagca gagagccagc gccacactgc    480

tgccctccgg ggccatggca ctgctgttca gctcaggcac aggggcacag cagaggtttg    540

ggaagcggtc tccccaccgg cactgggatt ggcgggtcca agcccagcaa ccggcttcgc    600

tccacaacac acaccacacc tgggactgtt tttaatacat agcaacagac tgggttattt    660

atttaagatg tgtattgtgt catatgaagt ttaagagaca taaatggcat tttgttattt    720

attaagacaa actccaattg ttctctggct gtttttttca gttgtgtcta gcaaaatact    780

tatctgccct ttgaaataaa atgtttttgt ttaaaaaatc tcagaacact c             831


<210>  10298
<211>  98
<212>  PRT
<213>  Homo sapiens

<400>  10298

Met Cys His Met Glu Lys Gln Asp Thr Arg Ala His Gln Thr Val Pro 
1               5                   10                  15


Ala Ser Arg Glu Ala Glu Ser Gln Arg His Thr Ala Ala Leu Arg Gly 
            20                  25                  30


His Gly Thr Ala Val Gln Leu Arg His Arg Gly Thr Ala Glu Val Trp 
        35                  40                  45


Glu Ala Val Ser Pro Pro Ala Leu Gly Leu Ala Gly Pro Ser Pro Ala 
    50                  55                  60


Thr Gly Phe Ala Pro Gln His Thr Pro His Leu Gly Leu Phe Leu Ile 
65                  70                  75                  80


His Ser Asn Arg Leu Gly Tyr Leu Phe Lys Met Cys Ile Val Ser Tyr 
                85                  90                  95


Glu Val 



<210>  10299
<211>  541
<212>  DNA
<213>  Homo sapiens

<400>  10299
ctgcatggaa agagtgacct ccctttgcct tttgcacacg cacctggaaa agacacagaa     60

gccaacctga gaacccctgg tgctatttta aaggagacat attgctgaac agcagtgaga    120

aaagtctgca ggaactgctg cctgagccaa gccagagaac cgaagaccgt catcccagcc    180

cctggccttc ctgctgccct ccggggccat ggcactgctg ttcagctcag gcacaggggc    240

acagcagagg tttgggaagc ggtctcccca ccggcactgg gattggcggg tccaagccca    300

gcaaccggct tcgctccaca acacacacca cacctgggac tgtttttaat acatagcaac    360

agactgggtt atttatttaa gatgtgtatt gtgtcatatg aagtttaaga gacataaatg    420

gcattttgtt atttattaag acaaactcca attgttctct ggctgttttt ttcagttgtg    480

tctagcaaaa tacttatctg ccctttgaaa taaaatgttt ttgtttaaaa aatctcagaa    540

c                                                                    541


<210>  10300
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  10300

Met Ala Leu Leu Phe Ser Ser Gly Thr Gly Ala Gln Gln Arg Phe Gly 
1               5                   10                  15


Lys Arg Ser Pro His Arg His Trp Asp Trp Arg Val Gln Ala Gln Gln 
            20                  25                  30


Pro Ala Ser Leu His Asn Thr His His Thr Trp Asp Cys Phe 
        35                  40                  45


<210>  10301
<211>  1835
<212>  DNA
<213>  Homo sapiens

<400>  10301
caggtcctgt gacaacaggt acgggccagc attgggacag gctttgcctg taagagggct     60

ggtctggggg gacatctgaa cccaattcag gaacacctca caggtctgcc agcagggcta    120

gacccggggt gagatccagg gcaacagggt ctgcctggga agctcagctc cggcactgcc    180

tggggcgtct ctgcctacac aggaccattc ctctcgcctg gactcctctt ggagtttgcc    240

aaggctggcc tctgcagaaa taggagactc ctggaggaag acagtggact tcagcaagct    300

gcaccaagga gaatccacag cggcagctgc cctgccaggc gcgggatctc ggtcaaggtg    360

gatcaacaca gcctcaggtg tgtgctctgc cccactgaga tggcaagtgc attcttttct    420

attcctacga ggaaagagca tccgaaagag cctgccttca cataggatga ataacagtgg    480

accttggctt tgcctcagtg ttatgtgcta ataaaccatg tattctatgc cctaaggaag    540

cccagagaga actggacaag ctggatatcc caaagagcat ggcactggcc caccacattg    600

attacattgc gctggccggg tgctaaccaa gaagcagcta acacactggg agtcttggta    660

agatgcctga gtgcctgcag ctggcagaca aatcctacaa agattctggg aactgccact    720

aataacactc ttggtgggga ggtcccatat cccataacca ggagcatact gggcctcctg    780

tccacagcaa agagccaatt actgcatctt gcatctccca tgaccaagag agacagacaa    840

tgccagtacg ccttctggag gcagcacgtt ccacacacat gaagactact ccagcctatg    900

taccattgat aggagaagct gtcggccttc cctgagcctg cagcaggtcg aggctgcagt    960

gctggcagcc ctgtgactca ggccctgcag ctggtcggac cctgtgttat gagaggtatc   1020

agacgtggga aagcaatgct gtgtgtttat ggcaaaccac tatgccagaa tcacagtgca   1080

ggcccctggg attcagaaac aaagccgtgc catctgcggc agaggattct gcgaaaaatt   1140

ctgaaaagtc cctgttgatg tgctcctggg gcctggggtg atggaatacc tgattgtgca   1200

tgtggaactg ctcagatgag ctggattctg tctcacccct gggtcatgag gttggggact   1260

cagaaataac ccatcacagg tgggagtgtg cgtgtggcag cagcagaagc aggagcagga   1320

ggccaagcag cggcagctgc ccagtacccc cccccaccct ccacagcagt ccccacagcc   1380

ccagtggagg aaccttctgg tgaactgagg agggagggac aagcccggcc tcagttcatg   1440

gaggtgtctg ctctgcctgt ggggccagcc caaatcgcct ggctgccata ctccagtctc   1500

agcaagctgc cctttaaaga gggtgatatg gtttggctct gtgtccccac ccaaatctca   1560

tcttgaactg taatccccag gtgatgaggg tgagacctga tgggaagtga ttggatcatg   1620

ggggctgttt tccccatgct gttctcgtga tagtgaagga gttctcatga gatctgatgg   1680

ttttataagt gtctggcaat tcccctgctt gcacttgtct ttctcaccca ccaccacgta   1740

agacgtgcct gcttcccctt ccgccatgat tgtaagtttc ctgaggcgtc cccagccatg   1800

cagaactgtg agtcaatgaa acctcttttc tttat                              1835


<210>  10302
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  10302

Met Trp Asn Cys Ser Asp Glu Leu Asp Ser Val Ser Pro Leu Gly His 
1               5                   10                  15


Glu Val Gly Asp Ser Glu Ile Thr His His Arg Trp Glu Cys Ala Cys 
            20                  25                  30


Gly Ser Ser Arg Ser Arg Ser Arg Arg Pro Ser Ser Gly Ser Cys Pro 
        35                  40                  45


Val Pro Pro Pro Thr Leu His Ser Ser Pro His Ser Pro Ser Gly Gly 
    50                  55                  60


Thr Phe Trp 
65


<210>  10303
<211>  1686
<212>  DNA
<213>  Homo sapiens

<400>  10303
caggtcctgt gacaacaggt acgggccagc attgggacag gctttgcctg taagagggct     60

ggtctggggg gacatctgaa cccaattcag gaacacctca caggtctgcc agcagggcta    120

gacccggggt gagatccagg gcaacagggt ctgcctggga agctcagctc cggcactgcc    180

tggggcgtct ctgcctacac aggaccattc ctctcgcctg gactcctctt ggagtttgcc    240

aaggctggcc tctgcagaaa taggagactc ctggaggaag acagtggact tcagcaagct    300

gcaccaagga gaatccacag cggcagctgc cctgccaggc gcgggatctc ggtcaaggtg    360

gatcaacaca gcctcaggtg tgtgctctgc cccactgaga tggcaagtgc attcttttct    420

attcctacga ggaaagagca tccgaaagag cctgccttca cataggatga ataacagtgg    480

accttggctt tgcctcagtg ttatgtgcta ataaaccatg tattctatgc cctaaggaag    540

cccagagaga actggacaag ctggatatcc caaagagcat ggcactggcc caccacattg    600

attacattgc gctggccggg tgctaaccaa gaagcagcta acacactggg agtcttggta    660

agatgcctga gtgcctgcag ctggcagaca aatcctacaa agattctggg aactgccact    720

aataacactc ttggtgggga ggtcccatat cccataacca ggagcatact gggcctcctg    780

tccacagcaa agagccaatt actgcatctt gcatctccca tgaccaagag agacagacaa    840

tgccagtacg ccttctggag gcagcacgtt ccacacacat gaagactact ccagcctatg    900

taccattgat aggagaagct gtcggccttc cctgagcctg cagcaggtcg aggctgcagt    960

gctggcagcc ctgtgactca ggccctgcag ctggtcggac cctgtgttat gagaggtatc   1020

agacgtggga aagcaatgct gtgtgtttat ggcaaaccac tatgccagaa tcacagtgca   1080

ggcccctggg attcagaaac aaagccgtgc catctgcggc agaggattct gcgaaaaatt   1140

ctgaaaagtc cctgttgatg tgctcctggg gcctggggtg atggaatacc tgattgtgca   1200

tgtggaactg ctcagatgag ctggattctg tctcacccct gggtcatgag gttggggact   1260

cagaaataac ccatcacagg tgggagtgtg cgtgtggcag cagcagaagc aggagcagga   1320

ggccaagcag cggcagctgc ccagtacccc cccccaccct ccacagcagt ccccacagcc   1380

ccagtggagg aaccttctgg tgaactgagg agggagggac aagcccggcc tcagttcatg   1440

gaggtgtctg ctctgcctgt ggggccagcc caaatcgcct ggctgccata ctccagtctc   1500

agcaagctgc cctttaaaga gggtgatatg gtttggctct gtgtccccac ccaaatctca   1560

tcttgaactg taatccccag gtgatgaggg tgagacctga tgggaagtga ttggatcatg   1620

ggggctgttt tccccatgct gttctcgtga tagtgaagga gttctcatga gatctgatgg   1680

ttttat                                                              1686


<210>  10304
<211>  67
<212>  PRT
<213>  Homo sapiens

<400>  10304

Met Trp Asn Cys Ser Asp Glu Leu Asp Ser Val Ser Pro Leu Gly His 
1               5                   10                  15


Glu Val Gly Asp Ser Glu Ile Thr His His Arg Trp Glu Cys Ala Cys 
            20                  25                  30


Gly Ser Ser Arg Ser Arg Ser Arg Arg Pro Ser Ser Gly Ser Cys Pro 
        35                  40                  45


Val Pro Pro Pro Thr Leu His Ser Ser Pro His Ser Pro Ser Gly Gly 
    50                  55                  60


Thr Phe Trp 
65


<210>  10305
<211>  706
<212>  DNA
<213>  Homo sapiens

<400>  10305
cctcttccga gctgggggtg gtgcaggggg ttggggaaaa atcagttcat caaacaagca     60

aaatgtattc agcgcctgct tgctgtagac caggcactgg gcagggcttg tgaaacggaa    120

ttggagccct ctggaccctg gaaaccttat gggagagagt taaaataaat cagacaggca    180

gaggtaaggc actttacctt ccgaaaggtg caccattgaa caccaagagg aatcagcctg    240

tcttgtacgt gtataatgaa cctgccacga cgagctcttc aggataacca ctgggcggga    300

tgcaccaaga atcagagaaa gggggtgccc tttgacctga agaggctggc attctctggg    360

ggagaccgac aagatgggat caataaatag acgggcagat ggtctgccct tgacttttgt    420

gcaaaaggag aagacactgg cacaaagatc tcacttccgt gtctgttgta gtagtattga    480

ttctcctggc tcagcctccc cgagtagctg ggattacagg catctgccac catgcccagt    540

taatttatgt atttttagta gggacggggt ttcaccatgt tggtcaggct ggtcttgaac    600

tcttgacctc aggtgatcct cctgcctggg cctcccaaag tgctgggatt acaagcgtga    660

gccactgcgc ctggccaaaa gtgtgttttt tacacctttg tgtgct                   706


<210>  10306
<211>  74
<212>  PRT
<213>  Homo sapiens

<400>  10306

Met Gly Ser Ile Asn Arg Arg Ala Asp Gly Leu Pro Leu Thr Phe Val 
1               5                   10                  15


Gln Lys Glu Lys Thr Leu Ala Gln Arg Ser His Phe Arg Val Cys Cys 
            20                  25                  30


Ser Ser Ile Asp Ser Pro Gly Ser Ala Ser Pro Ser Ser Trp Asp Tyr 
        35                  40                  45


Arg His Leu Pro Pro Cys Pro Val Asn Leu Cys Ile Phe Ser Arg Asp 
    50                  55                  60


Gly Val Ser Pro Cys Trp Ser Gly Trp Ser 
65                  70


<210>  10307
<211>  2820
<212>  DNA
<213>  Homo sapiens

<400>  10307
aggtgacggg ggcaaccccg cgtggtcaca cgagtgactt gaggtcactc ttcctccact     60

gcatgccttg caggaggcgg tgcagagggc catggtctga cgtgggtttt cacaggatcc    120

tcttggatgc tggaggaggg tgcatggaag gggccaggca gggaggccag tgagcagcag    180

ctgcagtcag ctttgcaaag tgtgatggga cttggaccac ggtcaggtgg acccatgagt    240

tggggtcctt cagagaagca gaccaatagt gaggagttgg ctcacatgag gacggaggct    300

gagaagtcct gccagctacc gcctgcaagc cggagccccg ggaaagctgg tggtgtggct    360

ccagtgcaag cctgagggca gcacccggga gctgatggtg gggacccagt cccagggcag    420

gagaaggcca gtgtcccagc ccaagcaggc aggtgggagg aaagaggcaa gttcctcctt    480

cctctgcctt cttgttctct tcagcccttc aaggggttgc atgatcccat gcacacaggg    540

aggcatctgc tcgccacagt ccaccactgc aaacgctggt ctcagccaga ggcacctcac    600

agactccccc agaaacagcg catccccagc tattgggcat cccgggctgg ccaggtggac    660

acacagacct caccagtgca gtcatgctcg ttggtcctga acagccttgg tggggaaggt    720

tccagaagtg gcgcctgctc tgtgcccccc acatcagccc cagggtctcc tggtatccta    780

aacctacatc cctgctcctg gcccggctgt cgggaatgca gccaatgttc gttcctcaga    840

atcaagataa aaacgaaggg aacctcctgc ctctgccagg caggccgcag gccaggctgg    900

ggaccccggg tggggtcgag gctggggagc ctgggtgggg atgaggctgg ggaccctggg    960

tagggtcgag gctggccacc ctgggtgggg tcgaggctgg ggaccctggg tggggacgag   1020

gctggagacc ctggctgggg tcgaggctgg ggaccctggg tggggttgag gctggggacc   1080

ttgggtgggg atgaggctgg ggacccttgg ggggacgagg ctggggacgc tggctggggt   1140

cgaatgcctc ctcagctcag gccttgggtc tttggggaac gtggtgactg agttcatata   1200

tgcatgagcg acgtttccaa ctgtctggaa acttcagaca gagtgtgaga ttctgcccgt   1260

gtgtcacagg gaaggaggct ggagatggag gagattctgg aggtaccaag cccccgcgct   1320

cccaagagcc gagtgggtcc agcctctgcc tccactctct gcccagactg cactttcttc   1380

tggtaccttc cagggtgcac acaggctcat tcctgtatgc agagctccct ctttaattcc   1440

caaaaagatc acaccaaagg agagtttcaa attagggcat cagagccaaa ttgaagattg   1500

gaggagctga gtccggaaga agggccaaga ctgcggagtg aggagctggt tgctggttcc   1560

caggtccctg gccagctcac cgtctccagc aagaaaggga caagcgaagg cacatgagga   1620

gaagagaagg gtctggccta tccttgaaga gtgatcacct tcccacgaga ttggaatact   1680

gggaaggaaa gtccgagcac cccgggaaag tctaaagggg gttcccaaag gcaaaagaag   1740

gtgtccaggc agcgtgtcct gccacggcca gcagctccca gcatgtgctc tagccgtcct   1800

ggcctggcgg gtcagagcca tggtcagtgg cagctactga accattgccc gtgggcatca   1860

tctgcctgtt ctctcttggg tctaaccagc atttctcgtg actattctga aaagactcca   1920

gtcacttcct ccaccacctc ttccgagctg ggggtggtgc agggggttgg ggaaaaatca   1980

gttcatcaaa caagcaaaat gtattcagcg cctgcttgct gtagaccagg cactgggcag   2040

ggcttgtgaa acggaattgg agccctctgg accctggaaa ccttatggga gagagttaaa   2100

ataaatcaga caggcagagg taaggcactt taccttccga aaggtgcacc attgaacacc   2160

aagaggaatc agcctgtctt gtacgtgtat aatgaacctg ccacgacgag ctcttcagga   2220

taaccactgg gcgggatgca ccaagaatca gagaaagggg gtgccctttg acctgaagag   2280

gctggcattc tctgggggag accgacaaga tgggatcaat aaatagacgg gcagatggtc   2340

tgcccttgac ttttgtgcaa aaggagaaga cactggcaca aagatctcac ttccgtgtct   2400

gttgtagtag tatttgattt atataccctc cacctgtttc tttttatggt cttggtaatt   2460

gcaaaattat tactagttgt aaatatttca aacaatgtgg tagaaaaggc aaagtccctc   2520

ttctagtaga gaaaatggag gccgggcaca gtggctcatg cctgtaatcc cagcactttg   2580

ggaggccgag gagggcagat cacaaggtca agagattgag accatcctgg ccaacatggc   2640

gaaactacat ctctactaaa aatacaaaaa ttagctgggc gtggtggcgc gtccctgtag   2700

tcccagctac tcgggaggct gaggtaggag aatcacttga acctgggagg tggaggttgc   2760

agtgagccga gatcgtgcca ttgcactcca gcctgggcga caagagtgaa attccacctc   2820


<210>  10308
<211>  144
<212>  PRT
<213>  Homo sapiens

<400>  10308

Met His Thr Gly Arg His Leu Leu Ala Thr Val His His Cys Lys Arg 
1               5                   10                  15


Trp Ser Gln Pro Glu Ala Pro His Arg Leu Pro Gln Lys Gln Arg Ile 
            20                  25                  30


Pro Ser Tyr Trp Ala Ser Arg Ala Gly Gln Val Asp Thr Gln Thr Ser 
        35                  40                  45


Pro Val Gln Ser Cys Ser Leu Val Leu Asn Ser Leu Gly Gly Glu Gly 
    50                  55                  60


Ser Arg Ser Gly Ala Cys Ser Val Pro Pro Thr Ser Ala Pro Gly Ser 
65                  70                  75                  80


Pro Gly Ile Leu Asn Leu His Pro Cys Ser Trp Pro Gly Cys Arg Glu 
                85                  90                  95


Cys Ser Gln Cys Ser Phe Leu Arg Ile Lys Ile Lys Thr Lys Gly Thr 
            100                 105                 110


Ser Cys Leu Cys Gln Ala Gly Arg Arg Pro Gly Trp Gly Pro Arg Val 
        115                 120                 125


Gly Ser Arg Leu Gly Ser Leu Gly Gly Asp Glu Ala Gly Asp Pro Gly 
    130                 135                 140


<210>  10309
<211>  2012
<212>  DNA
<213>  Homo sapiens

<400>  10309
gccgagcgga ggagaccctg cggcgcgcgg cggcggctcc cgggcgtccc gggcccggtg     60

gcggcgcggc tgtggttggc tgagcgccgc gggccgcccc ccgcccgccc cctcccctgc    120

tcccctcccc cgcctcccgc ggcggctggc gtcgggaaag tacagtaaaa agtccgagtg    180

cagccgccgg gcgcaggatg ggatccggct cctccagcta ccggcccaag gccatctacc    240

tggacatcga tggacgcatt cagaaggtaa tcttcagcaa gtactgcaac tccagcgaca    300

tcatggacct gttctgcatc gccaccggcc tgcctcggaa cacgaccatc tccctgctga    360

ccaccgacga cgccatggtc tccatcgacc ccaccatgcc cgcgaattca gaacgcactc    420

cgtacaaagt gagacctgtg gccatcaagc aactctccga gagagaagaa ttaatccaga    480

gcgtgctggc gcaggttgca gagcagttct caagagcatt caaaatcaat gaactgaaag    540

ctgaagttgc aaatcacttg gctgtcctag agaaacgcgt ggaattggaa ggactaaaag    600

tggtggagat tgagaaatgc aagagtgaca ttaagaagat gagggaggag ctggcggcca    660

gaagcagcag gaccaactgc ccctgtaagt acagtttttt ggataaccac aagaagttga    720

ctcctcgacg cgatgttccc acttacccca agtacctgct ctctccagag accatcgagg    780

ccctgcggaa gccgaccttt gacgtctggc tttgggagcc caatgagatg ctgagctgcc    840

tggagcacat gtaccacgac ctcgggctgg tcagggactt cagcatcaac cctgtcaccc    900

tcaggaggtg gctgttctgc gtccacgaca actacagaaa caaccccttc cacaacttcc    960

ggcactgctt ctgcgtggcc cagatgatgt acagcatggt ctggctctgc agtctccagg   1020

agaagttctc acaaacggat atcctgatcc taatgacagc ggccatctgc cacgatctgg   1080

accatcccgg ctacaacaac acgtaccaga tcaatgcccg cacagagctg gcggtccgct   1140

acaatgacat ctcaccgctg gagaaccacc actgcgccgt ggccttccag atcctcgccg   1200

agcctgagtg caacatcttc tccaacatcc cacctgatgg gttcaagcag atccgacagg   1260

gaatgatcac attaatcttg gccactgaca tggcaagaca tgcagaaatt atggattctt   1320

tcaaagagaa aatggagaat tttgactaca gcaacgagga gcacatgacc ctgctgaaga   1380

tgattttgat aaaatgctgt gatatctcta acgaggtccg tccaatggaa gtcgcagagc   1440

cttgggtgga ctgtttatta gaggaatatt ttatgcagag cgaccgtgag aagtcagaag   1500

gccttcctgt ggcaccgttc atggaccgag acaaagtgac caaggccaca gcccagattg   1560

ggttcatcaa gtttgtcctg atcccaatgt ttgaaacagt gaccaagctc ttccccatgg   1620

ttgaggagat catgctgcag ccactttggg aatcccgaga tcgctacgag gagctgaagc   1680

ggatagatga cgccatgaaa gagttacaga agaagactga cagcttgacg tctggggcca   1740

ccgagaagtc cagagagaga agcagagatg tgaaaaacag tgaaggagac tgtgcctgag   1800

gaaagcgggg ggcgtggctg cagttctgga cgggctggcc gagctgcgcg ggatccttgt   1860

gcagggaaga gctgccctgg gcacctggca ccacaagacc atgttttcta agaaccattt   1920

tgttcactga tacaaaaaaa aaaaaaggaa ttcatgatgc tgtacagaat tttattttta   1980

aactgtcttt taaataatat attcttatac gg                                 2012


<210>  10310
<211>  533
<212>  PRT
<213>  Homo sapiens

<400>  10310

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Glu Arg Glu Glu Leu Ile Gln Ser Val 
                85                  90                  95


Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu 
            100                 105                 110


Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val 
        115                 120                 125


Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp 
    130                 135                 140


Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn 
145                 150                 155                 160


Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro 
                165                 170                 175


Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr 
            180                 185                 190


Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro 
        195                 200                 205


Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu 
    210                 215                 220


Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe 
225                 230                 235                 240


Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His 
                245                 250                 255


Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser 
            260                 265                 270


Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala 
        275                 280                 285


Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln 
    290                 295                 300


Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro 
305                 310                 315                 320


Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro 
                325                 330                 335


Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile 
            340                 345                 350


Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His 
        355                 360                 365


Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr 
    370                 375                 380


Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys 
385                 390                 395                 400


Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp 
                405                 410                 415


Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys 
            420                 425                 430


Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr 
        435                 440                 445


Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met 
    450                 455                 460


Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu 
465                 470                 475                 480


Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile 
                485                 490                 495


Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser 
            500                 505                 510


Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser 
        515                 520                 525


Glu Gly Asp Cys Ala 
    530


<210>  10311
<211>  2107
<212>  DNA
<213>  Homo sapiens

<400>  10311
gccgagcgga ggagaccctg cggcgcgcgg cggcggctcc cgggcgtccc gggcccggtg     60

gcggcgcggc tgtggttggc tgagcgccgc gggccgcccc ccgcccgccc cctcccctgc    120

tcccctcccc cgcctcccgc ggcggctggc gtcgggaaag tacagtaaaa agtccgagtg    180

cagccgccgg gcgcaggatg ggatccggct cctccagcta ccggcccaag gccatctacc    240

tggacatcga tggacgcatt cagaaggtaa tcttcagcaa gtactgcaac tccagcgaca    300

tcatggacct gttctgcatc gccaccggcc tgcctcggaa cacgaccatc tccctgctga    360

ccaccgacga cgccatggtc tccatcgacc ccaccatgcc cgcgaattca gaacgcactc    420

cgtacaaagt gagacctgtg gccatcaagc aactctccga gagagaagaa ttaatccaga    480

gcgtgctggc gcaggttgca gagcagttct caagagcatt caaaatcaat gaactgaaag    540

ctgaagttgc aaatcacttg gctgtcctag agaaacgcgt ggaattggaa ggactaaaag    600

tggtggagat tgagaaatgc aagagtgaca ttaagaagat gagggaggag ctggcggcca    660

gaagcagcag gaccaactgc ccctgtaagt acagtttttt ggataaccac aagaagttga    720

ctcctcgacg cgatgttccc acttacccca agtacctgct ctctccagag accatcgagg    780

ccctgcggaa gccgaccttt gacgtctggc tttgggagcc caatgagatg ctgagctgcc    840

tggagcacat gtaccacgac ctcgggctgg tcagggactt cagcatcaac cctgtcaccc    900

tcaggaggtg gctgttctgc gtccacgaca actacagaaa caaccccttc cacaacttcc    960

ggcactgctt ctgcgtggcc cagatgatgt acagcatggt ctggctctgc agtctccagg   1020

agaagttctc acaaacggat atcctgatcc taatgacagc ggccatctgc cacgatctgg   1080

accatcccgg ctacaacaac acgtaccaga tcaatgcccg cacagagctg gcggtccgct   1140

acaatgacat ctcaccgctg gagaaccacc actgcgccgt ggccttccag atcctcgccg   1200

agcctgagtg caacatcttc tccaacatcc cacctgatgg gttcaagcag atccgacagg   1260

gaatgatcac attaatcttg gccactgaca tggcaagaca tgcagaaatt atggattctt   1320

tcaaagagaa aatggagaat tttgactaca gcaacgagga gcacatgacc ctgctgaaga   1380

tgattttgat aaaatgctgt gatatctcta acgaggtccg tccaatggaa gtcgcagagc   1440

cttgggtgga ctgtttatta gaggaatatt ttatgcagag cgaccgtgag aagtcagaag   1500

gccttcctgt ggcaccgttc atggaccgag acaaagtgac caaggccaca gcccagattg   1560

ggttcatcaa gtttgtcctg atcccaatgt ttgaaacagt gaccaagctc ttccccatgg   1620

ttgaggagat catgctgcag ccactttggg aatcccgaga tcgctacgag gagctgaagc   1680

ggatagatga cgccatgaaa gagttacaga agaagactga cagcttgacg tctggggcca   1740

ccgagaagtc cagagagaga agcagagatg tgaaaaacag tgaaggagac tgtgcctgag   1800

gaaagcgggg ggcgtggctg cagttctgga cgggctggcc gagctgcgcg ggatccttgt   1860

gcagggaaga gctgccctgg gcacctggca ccacaagacc atgttttcta agaaccattt   1920

tgttcactga tacaaaaaaa aaaaaaggaa ttcatgatgc tgtacagaat tttattttta   1980

aactgtcttt taaataatat attcttatac ggaaatgggt actgtacttc ttctttggta   2040

gagttgtgta tgctgcttcc ggtaagttct ctcatggaga cgaaggacac tgtgcttttc   2100

ccccaga                                                             2107


<210>  10312
<211>  533
<212>  PRT
<213>  Homo sapiens

<400>  10312

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Glu Arg Glu Glu Leu Ile Gln Ser Val 
                85                  90                  95


Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu 
            100                 105                 110


Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val 
        115                 120                 125


Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp 
    130                 135                 140


Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn 
145                 150                 155                 160


Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro 
                165                 170                 175


Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr 
            180                 185                 190


Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro 
        195                 200                 205


Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu 
    210                 215                 220


Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe 
225                 230                 235                 240


Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His 
                245                 250                 255


Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser 
            260                 265                 270


Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala 
        275                 280                 285


Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln 
    290                 295                 300


Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro 
305                 310                 315                 320


Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro 
                325                 330                 335


Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile 
            340                 345                 350


Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His 
        355                 360                 365


Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr 
    370                 375                 380


Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys 
385                 390                 395                 400


Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp 
                405                 410                 415


Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys 
            420                 425                 430


Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr 
        435                 440                 445


Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met 
    450                 455                 460


Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu 
465                 470                 475                 480


Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile 
                485                 490                 495


Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser 
            500                 505                 510


Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser 
        515                 520                 525


Glu Gly Asp Cys Ala 
    530


<210>  10313
<211>  1903
<212>  DNA
<213>  Homo sapiens

<400>  10313
cgcctcccgc ggcggctggc gtcgggaaag tacagtaaaa agtccgagtg cagccgccgg     60

gcgcaggatg ggatccggct cctccagcta ccggcccaag gccatctacc tggacatcga    120

tggacgcatt cagaaggtaa tcttcagcaa gtactgcaac tccagcgaca tcatggacct    180

gttctgcatc gccaccggcc tgcctcggaa cacgaccatc tccctgctga ccaccgacga    240

cgccatggtc tccatcgacc ccaccatgcc cgcgaattca gaacggaatg agctcattct    300

ctatacatca ctccgtaact tgttgttttt acctagtaag gagtcatggg cgtcccacca    360

gcactccgta caaagtgaga cctgtggcca tcaagcaact ctccgagcat tcaaaatcaa    420

tgaactgaaa gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaattgga    480

aggactaaaa gtggtggaga ttgagaaatg caagagtgac attaagaaga tgagggagga    540

gctggcggcc agaagcagca ggaccaactg cccctgtaag tacagttttt tggataacca    600

caagaagttg actcctcgac gcgatgttcc cacttacccc aagtacctgc tctctccaga    660

gaccatcgag gccctgcgga agccgacctt tgacgtctgg ctttgggagc ccaatgagat    720

gctgagctgc ctggagcaca tgtaccacga cctcgggctg gtcagggact tcagcatcaa    780

ccctgtcacc ctcaggaggt ggctgttctg cgtccacgac aactacagaa acaacccctt    840

ccacaacttc cggcactgct tctgcgtggc ccagatgatg tacagcatgg tctggctctg    900

cagtctccag gagaagttct cacaaacgga tatcctgatc ctaatgacag cggccatctg    960

ccacgatctg gaccatcccg gctacaacaa cacgtaccag atcaatgccc gcacagagct   1020

ggcggtccgc tacaatgaca tctcaccgct ggagaaccac cactgcgccg tggccttcca   1080

gatcctcgcc gagcctgagt gcaacatctt ctccaacatc ccacctgatg ggttcaagca   1140

gatccgacag ggaatgatca cattaatctt ggccactgac atggcaagac atgcagaaat   1200

tatggattct ttcaaagaga aaatggagaa ttttgactac agcaacgagg agcacatgac   1260

cctgctgaag atgattttga taaaatgctg tgatatctct aacgaggtcc gtccaatgga   1320

agtcgcagag ccttgggtgg actgtttatt agaggaatat tttatgcaga gcgaccgtga   1380

gaagtcagaa ggccttcctg tggcaccgtt catggaccga gacaaagtga ccaaggccac   1440

agcccagatt gggttcatca agtttgtcct gatcccaatg tttgaaacag tgaccaagct   1500

cttccccatg gttgaggaga tcatgctgca gccactttgg gaatcccgag atcgctacga   1560

ggagctgaag cggatagatg acgccatgaa agagttacag aagaagactg acagcttgac   1620

gtctggggcc accgagaagt ccagagagag aagcagagat gtgaaaaaca gtgaaggaga   1680

ctgtgcctga ggaaagcggg gggcgtggct gcagttctgg acgggctggc cgagctgcgc   1740

gggatccttg tgcagggaag agctgccctg ggcacctggc accacaagac catgttttct   1800

aagaaccatt ttgttcactg atacaaaaaa aaaaaaagga attcatgatg ctgtacagaa   1860

ttttattttt aaactgtctt ttaaataata tattcttata cgg                     1903


<210>  10314
<211>  540
<212>  PRT
<213>  Homo sapiens

<400>  10314

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Asn Glu Leu Ile Leu Tyr Thr 
65                  70                  75                  80


Ser Leu Arg Asn Leu Leu Phe Leu Pro Ser Lys Glu Ser Trp Ala Ser 
                85                  90                  95


His Gln His Ser Val Gln Ser Glu Thr Cys Gly His Gln Ala Thr Leu 
            100                 105                 110


Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu 
        115                 120                 125


Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu 
    130                 135                 140


Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala 
145                 150                 155                 160


Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp 
                165                 170                 175


Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys 
            180                 185                 190


Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe 
        195                 200                 205


Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His 
    210                 215                 220


Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val 
225                 230                 235                 240


Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn 
                245                 250                 255


Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr 
            260                 265                 270


Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp 
        275                 280                 285


Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro 
    290                 295                 300


Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val 
305                 310                 315                 320


Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala 
                325                 330                 335


Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro 
            340                 345                 350


Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu 
        355                 360                 365


Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu 
    370                 375                 380


Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu 
385                 390                 395                 400


Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro 
                405                 410                 415


Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe 
            420                 425                 430


Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe 
        435                 440                 445


Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile 
    450                 455                 460


Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro 
465                 470                 475                 480


Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg 
                485                 490                 495


Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys 
            500                 505                 510


Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg 
        515                 520                 525


Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
    530                 535                 540


<210>  10315
<211>  1958
<212>  DNA
<213>  Homo sapiens

<400>  10315
cgcctcccgc ggcggctggc gtcgggaaag tacagtaaaa agtccgagtg cagccgccgg     60

gcgcaggatg ggatccggct cctccagcta ccggcccaag gccatctacc tggacatcga    120

tggacgcatt cagaaggtaa tcttcagcaa gtactgcaac tccagcgaca tcatggacct    180

gttctgcatc gccaccggcc tgcctcggaa cacgaccatc tccctgctga ccaccgacga    240

cgccatggtc tccatcgacc ccaccatgcc cgcgaattca gaacggaatg agctcattct    300

ctatacatca ctccgtaact tgttgttttt acctagtaag gagtcatggg cgtcccacca    360

gcactccgta caaagtgaga cctgtggcca tcaagcaact ctccgagaga gaagaattaa    420

tccagagcgt gctggcgcag gttgcagagc agttctcaag agcattcaaa atcaatgaac    480

tgaaagctga agttgcaaat cacttggctg tcctagagaa acgcgtggaa ttggaaggac    540

taaaagtggt ggagattgag aaatgcaaga gtgacattaa gaagatgagg gaggagctgg    600

cggccagaag cagcaggacc aactgcccct gtaagtacag ttttttggat aaccacaaga    660

agttgactcc tcgacgcgat gttcccactt accccaagta cctgctctct ccagagacca    720

tcgaggccct gcggaagccg acctttgacg tctggctttg ggagcccaat gagatgctga    780

gctgcctgga gcacatgtac cacgacctcg ggctggtcag ggacttcagc atcaaccctg    840

tcaccctcag gaggtggctg ttctgcgtcc acgacaacta cagaaacaac cccttccaca    900

acttccggca ctgcttctgc gtggcccaga tgatgtacag catggtctgg ctctgcagtc    960

tccaggagaa gttctcacaa acggatatcc tgatcctaat gacagcggcc atctgccacg   1020

atctggacca tcccggctac aacaacacgt accagatcaa tgcccgcaca gagctggcgg   1080

tccgctacaa tgacatctca ccgctggaga accaccactg cgccgtggcc ttccagatcc   1140

tcgccgagcc tgagtgcaac atcttctcca acatcccacc tgatgggttc aagcagatcc   1200

gacagggaat gatcacatta atcttggcca ctgacatggc aagacatgca gaaattatgg   1260

attctttcaa agagaaaatg gagaattttg actacagcaa cgaggagcac atgaccctgc   1320

tgaagatgat tttgataaaa tgctgtgata tctctaacga ggtccgtcca atggaagtcg   1380

cagagccttg ggtggactgt ttattagagg aatattttat gcagagcgac cgtgagaagt   1440

cagaaggcct tcctgtggca ccgttcatgg accgagacaa agtgaccaag gccacagccc   1500

agattgggtt catcaagttt gtcctgatcc caatgtttga aacagtgacc aagctcttcc   1560

ccatggttga ggagatcatg ctgcagccac tttgggaatc ccgagatcgc tacgaggagc   1620

tgaagcggat agatgacgcc atgaaagagt tacagaagaa gactgacagc ttgacgtctg   1680

gggccaccga gaagtccaga gagagaagca gagatgtgaa aaacagtgaa ggagactgtg   1740

cctgaggaaa gcggggggcg tggctgcagt tctggacggg ctggccgagc tgcgcgggat   1800

ccttgtgcag ggaagagctg ccctgggcac ctggcaccac aagaccatgt tttctaagaa   1860

ccattttgtt cactgataca aaaaaaaaaa aaggaattca tgatgctgta cagaatttta   1920

tttttaaact gtcttttaaa taatatattc ttatacgg                           1958


<210>  10316
<211>  485
<212>  PRT
<213>  Homo sapiens

<400>  10316

Met Ser Ser Phe Ser Ile His His Ser Val Thr Cys Cys Phe Tyr Leu 
1               5                   10                  15


Val Arg Ser His Gly Arg Pro Thr Ser Thr Pro Tyr Lys Val Arg Pro 
            20                  25                  30


Val Ala Ile Lys Gln Leu Ser Glu Arg Glu Glu Leu Ile Gln Ser Val 
        35                  40                  45


Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu 
    50                  55                  60


Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val 
65                  70                  75                  80


Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp 
                85                  90                  95


Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn 
            100                 105                 110


Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro 
        115                 120                 125


Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr 
    130                 135                 140


Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro 
145                 150                 155                 160


Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu 
                165                 170                 175


Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe 
            180                 185                 190


Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His 
        195                 200                 205


Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser 
    210                 215                 220


Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala 
225                 230                 235                 240


Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln 
                245                 250                 255


Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro 
            260                 265                 270


Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro 
        275                 280                 285


Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile 
    290                 295                 300


Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His 
305                 310                 315                 320


Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr 
                325                 330                 335


Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys 
            340                 345                 350


Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp 
        355                 360                 365


Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys 
    370                 375                 380


Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr 
385                 390                 395                 400


Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met 
                405                 410                 415


Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu 
            420                 425                 430


Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile 
        435                 440                 445


Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser 
    450                 455                 460


Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser 
465                 470                 475                 480


Glu Gly Asp Cys Ala 
                485


<210>  10317
<211>  1998
<212>  DNA
<213>  Homo sapiens

<400>  10317
cgcctcccgc ggcggctggc gtcgggaaag tacagtaaaa agtccgagtg cagccgccgg     60

gcgcaggatg ggatccggct cctccagcta ccggcccaag gccatctacc tggacatcga    120

tggacgcatt cagaaggtaa tcttcagcaa gtactgcaac tccagcgaca tcatggacct    180

gttctgcatc gccaccggcc tgcctcggaa cacgaccatc tccctgctga ccaccgacga    240

cgccatggtc tccatcgacc ccaccatgcc cgcgaattca gaacggaatg agctcattct    300

ctatacatca ctccgtaact tgttgttttt acctagtaag gagtcatggg cgtcccacca    360

gcactccgta caaagtgaga cctgtggcca tcaagcaact ctccgagcat tcaaaatcaa    420

tgaactgaaa gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaattgga    480

aggactaaaa gtggtggaga ttgagaaatg caagagtgac attaagaaga tgagggagga    540

gctggcggcc agaagcagca ggaccaactg cccctgtaag tacagttttt tggataacca    600

caagaagttg actcctcgac gcgatgttcc cacttacccc aagtacctgc tctctccaga    660

gaccatcgag gccctgcgga agccgacctt tgacgtctgg ctttgggagc ccaatgagat    720

gctgagctgc ctggagcaca tgtaccacga cctcgggctg gtcagggact tcagcatcaa    780

ccctgtcacc ctcaggaggt ggctgttctg cgtccacgac aactacagaa acaacccctt    840

ccacaacttc cggcactgct tctgcgtggc ccagatgatg tacagcatgg tctggctctg    900

cagtctccag gagaagttct cacaaacgga tatcctgatc ctaatgacag cggccatctg    960

ccacgatctg gaccatcccg gctacaacaa cacgtaccag atcaatgccc gcacagagct   1020

ggcggtccgc tacaatgaca tctcaccgct ggagaaccac cactgcgccg tggccttcca   1080

gatcctcgcc gagcctgagt gcaacatctt ctccaacatc ccacctgatg ggttcaagca   1140

gatccgacag ggaatgatca cattaatctt ggccactgac atggcaagac atgcagaaat   1200

tatggattct ttcaaagaga aaatggagaa ttttgactac agcaacgagg agcacatgac   1260

cctgctgaag atgattttga taaaatgctg tgatatctct aacgaggtcc gtccaatgga   1320

agtcgcagag ccttgggtgg actgtttatt agaggaatat tttatgcaga gcgaccgtga   1380

gaagtcagaa ggccttcctg tggcaccgtt catggaccga gacaaagtga ccaaggccac   1440

agcccagatt gggttcatca agtttgtcct gatcccaatg tttgaaacag tgaccaagct   1500

cttccccatg gttgaggaga tcatgctgca gccactttgg gaatcccgag atcgctacga   1560

ggagctgaag cggatagatg acgccatgaa agagttacag aagaagactg acagcttgac   1620

gtctggggcc accgagaagt ccagagagag aagcagagat gtgaaaaaca gtgaaggaga   1680

ctgtgcctga ggaaagcggg gggcgtggct gcagttctgg acgggctggc cgagctgcgc   1740

gggatccttg tgcagggaag agctgccctg ggcacctggc accacaagac catgttttct   1800

aagaaccatt ttgttcactg atacaaaaaa aaaaaaagga attcatgatg ctgtacagaa   1860

ttttattttt aaactgtctt ttaaataata tattcttata cggaaatggg tactgtactt   1920

cttctttggt agagttgtgt atgctgcttc cggtaagttc tctcatggag acgaaggaca   1980

ctgtgctttt cccccaga                                                 1998


<210>  10318
<211>  540
<212>  PRT
<213>  Homo sapiens

<400>  10318

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Asn Glu Leu Ile Leu Tyr Thr 
65                  70                  75                  80


Ser Leu Arg Asn Leu Leu Phe Leu Pro Ser Lys Glu Ser Trp Ala Ser 
                85                  90                  95


His Gln His Ser Val Gln Ser Glu Thr Cys Gly His Gln Ala Thr Leu 
            100                 105                 110


Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu 
        115                 120                 125


Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu 
    130                 135                 140


Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala 
145                 150                 155                 160


Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp 
                165                 170                 175


Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys 
            180                 185                 190


Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe 
        195                 200                 205


Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His 
    210                 215                 220


Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val 
225                 230                 235                 240


Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn 
                245                 250                 255


Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr 
            260                 265                 270


Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp 
        275                 280                 285


Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro 
    290                 295                 300


Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val 
305                 310                 315                 320


Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala 
                325                 330                 335


Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro 
            340                 345                 350


Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu 
        355                 360                 365


Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu 
    370                 375                 380


Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu 
385                 390                 395                 400


Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro 
                405                 410                 415


Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe 
            420                 425                 430


Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe 
        435                 440                 445


Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile 
    450                 455                 460


Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro 
465                 470                 475                 480


Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg 
                485                 490                 495


Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys 
            500                 505                 510


Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg 
        515                 520                 525


Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
    530                 535                 540


<210>  10319
<211>  1752
<212>  DNA
<213>  Homo sapiens

<400>  10319
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggaacacga ccatctccct gctgaccacc gacgacgcca tggtctccat    180

cgaccccacc atgcccgcga attcagaacg cactccgtac aaagtgagac ctgtggccat    240

caagcaactc tccgagcatt caaaatcaat gaactgaaag ctgaagttgc aaatcacttg    300

gctgtcctag agaaacgcgt ggaattggaa ggactaaaag tggtggagat tgagaaatgc    360

aagagtgaca ttaagaagat gagggaggag ctggcggcca gaagcagcag gaccaactgc    420

ccctgtaagt acagtttttt ggataaccac aagaagttga ctcctcgacg cgatgttccc    480

acttacccca agtacctgct ctctccagag accatcgagg ccctgcggaa gccgaccttt    540

gacgtctggc tttgggagcc caatgagatg ctgagctgcc tggagcacat gtaccacgac    600

ctcgggctgg tcagggactt cagcatcaac cctgtcaccc tcaggaggtg gctgttctgc    660

gtccacgaca actacagaaa caaccccttc cacaacttcc ggcactgctt ctgcgtggcc    720

cagatgatgt acagcatggt ctggctctgc agtctccagg agaagttctc acaaacggat    780

atcctgatcc taatgacagc ggccatctgc cacgatctgg accatcccgg ctacaacaac    840

acgtaccaga tcaatgcccg cacagagctg gcggtccgct acaatgacat ctcaccgctg    900

gagaaccacc actgcgccgt ggccttccag atcctcgccg agcctgagtg caacatcttc    960

tccaacatcc cacctgatgg gttcaagcag atccgacagg gaatgatcac attaatcttg   1020

gccactgaca tggcaagaca tgcagaaatt atggattctt tcaaagagaa aatggagaat   1080

tttgactaca gcaacgagga gcacatgacc ctgctgaaga tgattttgat aaaatgctgt   1140

gatatctcta acgaggtccg tccaatggaa gtcgcagagc cttgggtgga ctgtttatta   1200

gaggaatatt ttatgcagag cgaccgtgag aagtcagaag gccttcctgt ggcaccgttc   1260

atggaccgag acaaagtgac caaggccaca gcccagattg ggttcatcaa gtttgtcctg   1320

atcccaatgt ttgaaacagt gaccaagctc ttccccatgg ttgaggagat catgctgcag   1380

ccactttggg aatcccgaga tcgctacgag gagctgaagc ggatagatga cgccatgaaa   1440

gagttacaga agaagactga cagcttgacg tctggggcca ccgagaagtc cagagagaga   1500

agcagagatg tgaaaaacag tgaaggagac tgtgcctgag gaaagcgggg ggcgtggctg   1560

cagttctgga cgggctggcc gagctgcgcg ggatccttgt gcagggaaga gctgccctgg   1620

gcacctggca ccacaagacc atgttttcta agaaccattt tgttcactga tacaaaaaaa   1680

aaaaaaggaa ttcatgatgc tgtacagaat tttattttta aactgtcttt taaataatat   1740

attcttatac gg                                                       1752


<210>  10320
<211>  491
<212>  PRT
<213>  Homo sapiens

<400>  10320

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Glu His Asp His Leu Pro Ala Asp His 
            20                  25                  30


Arg Arg Arg His Gly Leu His Arg Pro His His Ala Arg Glu Phe Arg 
        35                  40                  45


Thr His Ser Val Gln Ser Glu Thr Cys Gly His Gln Ala Thr Leu Arg 
    50                  55                  60


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
65                  70                  75                  80


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
                85                  90                  95


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
            100                 105                 110


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
        115                 120                 125


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
    130                 135                 140


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
145                 150                 155                 160


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
                165                 170                 175


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
            180                 185                 190


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
        195                 200                 205


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
    210                 215                 220


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
225                 230                 235                 240


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
                245                 250                 255


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
            260                 265                 270


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
        275                 280                 285


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
    290                 295                 300


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
305                 310                 315                 320


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
                325                 330                 335


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
            340                 345                 350


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
        355                 360                 365


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
    370                 375                 380


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
385                 390                 395                 400


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
                405                 410                 415


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
            420                 425                 430


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
        435                 440                 445


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
    450                 455                 460


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
465                 470                 475                 480


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
                485                 490


<210>  10321
<211>  1808
<212>  DNA
<213>  Homo sapiens

<400>  10321
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agcactccgt acaaagtgag acctgtggcc atcaagcaac tctccgcaaa    180

agaatgcaga ttttgcatta tctaaagagg cggttccgtg agcccactgt gctgagtcac    240

atatattcca tcggtagaga gaagaattaa tccagagcgt gctggcgcag gttgcagagc    300

agttctcaag agcattcaaa atcaatgaac tgaaagctga agttgcaaat cacttggctg    360

tcctagagaa acgcgtggaa ttggaaggac taaaagtggt ggagattgag aaatgcaaga    420

gtgacattaa gaagatgagg gaggagctgg cggccagaag cagcaggacc aactgcccct    480

gtaagtacag ttttttggat aaccacaaga agttgactcc tcgacgcgat gttcccactt    540

accccaagta cctgctctct ccagagacca tcgaggccct gcggaagccg acctttgacg    600

tctggctttg ggagcccaat gagatgctga gctgcctgga gcacatgtac cacgacctcg    660

ggctggtcag ggacttcagc atcaaccctg tcaccctcag gaggtggctg ttctgcgtcc    720

acgacaacta cagaaacaac cccttccaca acttccggca ctgcttctgc gtggcccaga    780

tgatgtacag catggtctgg ctctgcagtc tccaggagaa gttctcacaa acggatatcc    840

tgatcctaat gacagcggcc atctgccacg atctggacca tcccggctac aacaacacgt    900

accagatcaa tgcccgcaca gagctggcgg tccgctacaa tgacatctca ccgctggaga    960

accaccactg cgccgtggcc ttccagatcc tcgccgagcc tgagtgcaac atcttctcca   1020

acatcccacc tgatgggttc aagcagatcc gacagggaat gatcacatta atcttggcca   1080

ctgacatggc aagacatgca gaaattatgg attctttcaa agagaaaatg gagaattttg   1140

actacagcaa cgaggagcac atgaccctgc tgaagatgat tttgataaaa tgctgtgata   1200

tctctaacga ggtccgtcca atggaagtcg cagagccttg ggtggactgt ttattagagg   1260

aatattttat gcagagcgac cgtgagaagt cagaaggcct tcctgtggca ccgttcatgg   1320

accgagacaa agtgaccaag gccacagccc agattgggtt catcaagttt gtcctgatcc   1380

caatgtttga aacagtgacc aagctcttcc ccatggttga ggagatcatg ctgcagccac   1440

tttgggaatc ccgagatcgc tacgaggagc tgaagcggat agatgacgcc atgaaagagt   1500

tacagaagaa gactgacagc ttgacgtctg gggccaccga gaagtccaga gagagaagca   1560

gagatgtgaa aaacagtgaa ggagactgtg cctgaggaaa gcggggggcg tggctgcagt   1620

tctggacggg ctggccgagc tgcgcgggat ccttgtgcag ggaagagctg ccctgggcac   1680

ctggcaccac aagaccatgt tttctaagaa ccattttgtt cactgataca aaaaaaaaaa   1740

aaggaattca tgatgctgta cagaatttta tttttaaact gtcttttaaa taatatattc   1800

ttatacgg                                                            1808


<210>  10322
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10322

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10323
<211>  1630
<212>  DNA
<213>  Homo sapiens

<400>  10323
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agagcattca aaatcaatga actgaaagct gaagttgcaa atcacttggc    180

tgtcctagag aaacgcgtgg aattggaagg actaaaagtg gtggagattg agaaatgcaa    240

gagtgacatt aagaagatga gggaggagct ggcggccaga agcagcagga ccaactgccc    300

ctgtaagtac agttttttgg ataaccacaa gaagttgact cctcgacgcg atgttcccac    360

ttaccccaag tacctgctct ctccagagac catcgaggcc ctgcggaagc cgacctttga    420

cgtctggctt tgggagccca atgagatgct gagctgcctg gagcacatgt accacgacct    480

cgggctggtc agggacttca gcatcaaccc tgtcaccctc aggaggtggc tgttctgcgt    540

ccacgacaac tacagaaaca accccttcca caacttccgg cactgcttct gcgtggccca    600

gatgatgtac agcatggtct ggctctgcag tctccaggag aagttctcac aaacggatat    660

cctgatccta atgacagcgg ccatctgcca cgatctggac catcccggct acaacaacac    720

gtaccagatc aatgcccgca cagagctggc ggtccgctac aatgacatct caccgctgga    780

gaaccaccac tgcgccgtgg ccttccagat cctcgccgag cctgagtgca acatcttctc    840

caacatccca cctgatgggt tcaagcagat ccgacaggga atgatcacat taatcttggc    900

cactgacatg gcaagacatg cagaaattat ggattctttc aaagagaaaa tggagaattt    960

tgactacagc aacgaggagc acatgaccct gctgaagatg attttgataa aatgctgtga   1020

tatctctaac gaggtccgtc caatggaagt cgcagagcct tgggtggact gtttattaga   1080

ggaatatttt atgcagagcg accgtgagaa gtcagaaggc cttcctgtgg caccgttcat   1140

ggaccgagac aaagtgacca aggccacagc ccagattggg ttcatcaagt ttgtcctgat   1200

cccaatgttt gaaacagtga ccaagctctt ccccatggtt gaggagatca tgctgcagcc   1260

actttgggaa tcccgagatc gctacgagga gctgaagcgg atagatgacg ccatgaaaga   1320

gttacagaag aagactgaca gcttgacgtc tggggccacc gagaagtcca gagagagaag   1380

cagagatgtg aaaaacagtg aaggagactg tgcctgagga aagcgggggg cgtggctgca   1440

gttctggacg ggctggccga gctgcgcggg atccttgtgc agggaagagc tgccctgggc   1500

acctggcacc acaagaccat gttttctaag aaccattttg ttcactgata caaaaaaaaa   1560

aaaaggaatt catgatgctg tacagaattt tatttttaaa ctgtctttta aataatatat   1620

tcttatacgg                                                          1630


<210>  10324
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  10324

Met Asp Ala Phe Arg Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
1               5                   10                  15


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
            20                  25                  30


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
        35                  40                  45


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
    50                  55                  60


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
65                  70                  75                  80


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
                85                  90                  95


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
            100                 105                 110


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
        115                 120                 125


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
    130                 135                 140


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
145                 150                 155                 160


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
                165                 170                 175


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
            180                 185                 190


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
        195                 200                 205


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
    210                 215                 220


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
225                 230                 235                 240


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
                245                 250                 255


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
            260                 265                 270


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
        275                 280                 285


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
    290                 295                 300


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
305                 310                 315                 320


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
                325                 330                 335


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
            340                 345                 350


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
        355                 360                 365


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
    370                 375                 380


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
385                 390                 395                 400


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
                405                 410                 415


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
            420                 425                 430


Ala 



<210>  10325
<211>  1745
<212>  DNA
<213>  Homo sapiens

<400>  10325
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggtaatctt cagcaagtac tgcaactcca gcgacatcat ggacctgttc    180

tgcatcgcca ccggcctgcc tcgcactccg tacaaagtga gacctgtggc catcaagcaa    240

ctctccgagc attcaaaatc aatgaactga aagctgaagt tgcaaatcac ttggctgtcc    300

tagagaaacg cgtggaattg gaaggactaa aagtggtgga gattgagaaa tgcaagagtg    360

acattaagaa gatgagggag gagctggcgg ccagaagcag caggaccaac tgcccctgta    420

agtacagttt tttggataac cacaagaagt tgactcctcg acgcgatgtt cccacttacc    480

ccaagtacct gctctctcca gagaccatcg aggccctgcg gaagccgacc tttgacgtct    540

ggctttggga gcccaatgag atgctgagct gcctggagca catgtaccac gacctcgggc    600

tggtcaggga cttcagcatc aaccctgtca ccctcaggag gtggctgttc tgcgtccacg    660

acaactacag aaacaacccc ttccacaact tccggcactg cttctgcgtg gcccagatga    720

tgtacagcat ggtctggctc tgcagtctcc aggagaagtt ctcacaaacg gatatcctga    780

tcctaatgac agcggccatc tgccacgatc tggaccatcc cggctacaac aacacgtacc    840

agatcaatgc ccgcacagag ctggcggtcc gctacaatga catctcaccg ctggagaacc    900

accactgcgc cgtggccttc cagatcctcg ccgagcctga gtgcaacatc ttctccaaca    960

tcccacctga tgggttcaag cagatccgac agggaatgat cacattaatc ttggccactg   1020

acatggcaag acatgcagaa attatggatt ctttcaaaga gaaaatggag aattttgact   1080

acagcaacga ggagcacatg accctgctga agatgatttt gataaaatgc tgtgatatct   1140

ctaacgaggt ccgtccaatg gaagtcgcag agccttgggt ggactgttta ttagaggaat   1200

attttatgca gagcgaccgt gagaagtcag aaggccttcc tgtggcaccg ttcatggacc   1260

gagacaaagt gaccaaggcc acagcccaga ttgggttcat caagtttgtc ctgatcccaa   1320

tgtttgaaac agtgaccaag ctcttcccca tggttgagga gatcatgctg cagccacttt   1380

gggaatcccg agatcgctac gaggagctga agcggataga tgacgccatg aaagagttac   1440

agaagaagac tgacagcttg acgtctgggg ccaccgagaa gtccagagag agaagcagag   1500

atgtgaaaaa cagtgaagga gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct   1560

ggacgggctg gccgagctgc gcgggatcct tgtgcaggga agagctgccc tgggcacctg   1620

gcaccacaag accatgtttt ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag   1680

gaattcatga tgctgtacag aattttattt ttaaactgtc ttttaaataa tatattctta   1740

tacgg                                                               1745


<210>  10326
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10326

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10327
<211>  1729
<212>  DNA
<213>  Homo sapiens

<400>  10327
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agcactccgt acaaagtgag acctgtggcc atcaagcaac tctccgagag    180

agaagaatta atccagagcg tgctggcgca ggttgcagag cagttctcaa gagcattcaa    240

aatcaatgaa ctgaaagctg aagttgcaaa tcacttggct gtcctagaga aacgcgtgga    300

attggaagga ctaaaagtgg tggagattga gaaatgcaag agtgacatta agaagatgag    360

ggaggagctg gcggccagaa gcagcaggac caactgcccc tgtaagtaca gttttttgga    420

taaccacaag aagttgactc ctcgacgcga tgttcccact taccccaagt acctgctctc    480

tccagagacc atcgaggccc tgcggaagcc gacctttgac gtctggcttt gggagcccaa    540

tgagatgctg agctgcctgg agcacatgta ccacgacctc gggctggtca gggacttcag    600

catcaaccct gtcaccctca ggaggtggct gttctgcgtc cacgacaact acagaaacaa    660

ccccttccac aacttccggc actgcttctg cgtggcccag atgatgtaca gcatggtctg    720

gctctgcagt ctccaggaga agttctcaca aacggatatc ctgatcctaa tgacagcggc    780

catctgccac gatctggacc atcccggcta caacaacacg taccagatca atgcccgcac    840

agagctggcg gtccgctaca atgacatctc accgctggag aaccaccact gcgccgtggc    900

cttccagatc ctcgccgagc ctgagtgcaa catcttctcc aacatcccac ctgatgggtt    960

caagcagatc cgacagggaa tgatcacatt aatcttggcc actgacatgg caagacatgc   1020

agaaattatg gattctttca aagagaaaat ggagaatttt gactacagca acgaggagca   1080

catgaccctg ctgaagatga ttttgataaa atgctgtgat atctctaacg aggtccgtcc   1140

aatggaagtc gcagagcctt gggtggactg tttattagag gaatatttta tgcagagcga   1200

ccgtgagaag tcagaaggcc ttcctgtggc accgttcatg gaccgagaca aagtgaccaa   1260

ggccacagcc cagattgggt tcatcaagtt tgtcctgatc ccaatgtttg aaacagtgac   1320

caagctcttc cccatggttg aggagatcat gctgcagcca ctttgggaat cccgagatcg   1380

ctacgaggag ctgaagcgga tagatgacgc catgaaagag ttacagaaga agactgacag   1440

cttgacgtct ggggccaccg agaagtccag agagagaagc agagatgtga aaaacagtga   1500

aggagactgt gcctgaggaa agcggggggc gtggctgcag ttctggacgg gctggccgag   1560

ctgcgcggga tccttgtgca gggaagagct gccctgggca cctggcacca caagaccatg   1620

ttttctaaga accattttgt tcactgatac aaaaaaaaaa aaaggaattc atgatgctgt   1680

acagaatttt atttttaaac tgtcttttaa ataatatatt cttatacgg               1729


<210>  10328
<211>  466
<212>  PRT
<213>  Homo sapiens

<400>  10328

Met Asp Ala Phe Arg Ser Thr Pro Tyr Lys Val Arg Pro Val Ala Ile 
1               5                   10                  15


Lys Gln Leu Ser Glu Arg Glu Glu Leu Ile Gln Ser Val Leu Ala Gln 
            20                  25                  30


Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala 
        35                  40                  45


Glu Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu 
    50                  55                  60


Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys 
65                  70                  75                  80


Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
                85                  90                  95


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            100                 105                 110


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        115                 120                 125


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    130                 135                 140


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
145                 150                 155                 160


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                165                 170                 175


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            180                 185                 190


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        195                 200                 205


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    210                 215                 220


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
225                 230                 235                 240


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                245                 250                 255


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            260                 265                 270


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        275                 280                 285


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    290                 295                 300


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
305                 310                 315                 320


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                325                 330                 335


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            340                 345                 350


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        355                 360                 365


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    370                 375                 380


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
385                 390                 395                 400


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                405                 410                 415


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            420                 425                 430


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        435                 440                 445


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    450                 455                 460


Cys Ala 
465


<210>  10329
<211>  1865
<212>  DNA
<213>  Homo sapiens

<400>  10329
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agctggtgtc gaggacaaga gaaccacaag ccgtggccag tctgctgaga    180

gaccactgag ggacagacgg gttgtgggcc tggagcagcc ccggagggaa ggagcatttg    240

aaagtggaca ggtagagccc aggcccagag agccccaggg ctgctaccag gaaggccagc    300

gcatccctcc agagagagaa gaattaatcc agagcgtgct ggcgcaggtt gcagagcagt    360

tctcaagagc attcaaaatc aatgaactga aagctgaagt tgcaaatcac ttggctgtcc    420

tagagaaacg cgtggaattg gaaggactaa aagtggtgga gattgagaaa tgcaagagtg    480

acattaagaa gatgagggag gagctggcgg ccagaagcag caggaccaac tgcccctgta    540

agtacagttt tttggataac cacaagaagt tgactcctcg acgcgatgtt cccacttacc    600

ccaagtacct gctctctcca gagaccatcg aggccctgcg gaagccgacc tttgacgtct    660

ggctttggga gcccaatgag atgctgagct gcctggagca catgtaccac gacctcgggc    720

tggtcaggga cttcagcatc aaccctgtca ccctcaggag gtggctgttc tgcgtccacg    780

acaactacag aaacaacccc ttccacaact tccggcactg cttctgcgtg gcccagatga    840

tgtacagcat ggtctggctc tgcagtctcc aggagaagtt ctcacaaacg gatatcctga    900

tcctaatgac agcggccatc tgccacgatc tggaccatcc cggctacaac aacacgtacc    960

agatcaatgc ccgcacagag ctggcggtcc gctacaatga catctcaccg ctggagaacc   1020

accactgcgc cgtggccttc cagatcctcg ccgagcctga gtgcaacatc ttctccaaca   1080

tcccacctga tgggttcaag cagatccgac agggaatgat cacattaatc ttggccactg   1140

acatggcaag acatgcagaa attatggatt ctttcaaaga gaaaatggag aattttgact   1200

acagcaacga ggagcacatg accctgctga agatgatttt gataaaatgc tgtgatatct   1260

ctaacgaggt ccgtccaatg gaagtcgcag agccttgggt ggactgttta ttagaggaat   1320

attttatgca gagcgaccgt gagaagtcag aaggccttcc tgtggcaccg ttcatggacc   1380

gagacaaagt gaccaaggcc acagcccaga ttgggttcat caagtttgtc ctgatcccaa   1440

tgtttgaaac agtgaccaag ctcttcccca tggttgagga gatcatgctg cagccacttt   1500

gggaatcccg agatcgctac gaggagctga agcggataga tgacgccatg aaagagttac   1560

agaagaagac tgacagcttg acgtctgggg ccaccgagaa gtccagagag agaagcagag   1620

atgtgaaaaa cagtgaagga gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct   1680

ggacgggctg gccgagctgc gcgggatcct tgtgcaggga agagctgccc tgggcacctg   1740

gcaccacaag accatgtttt ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag   1800

gaattcatga tgctgtacag aattttattt ttaaactgtc ttttaaataa tatattctta   1860

tacgg                                                               1865


<210>  10330
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10330

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10331
<211>  1674
<212>  DNA
<213>  Homo sapiens

<400>  10331
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agcactccgt acaaagtgag acctgtggcc atcaagcaac tctccgagca    180

ttcaaaatca atgaactgaa agctgaagtt gcaaatcact tggctgtcct agagaaacgc    240

gtggaattgg aaggactaaa agtggtggag attgagaaat gcaagagtga cattaagaag    300

atgagggagg agctggcggc cagaagcagc aggaccaact gcccctgtaa gtacagtttt    360

ttggataacc acaagaagtt gactcctcga cgcgatgttc ccacttaccc caagtacctg    420

ctctctccag agaccatcga ggccctgcgg aagccgacct ttgacgtctg gctttgggag    480

cccaatgaga tgctgagctg cctggagcac atgtaccacg acctcgggct ggtcagggac    540

ttcagcatca accctgtcac cctcaggagg tggctgttct gcgtccacga caactacaga    600

aacaacccct tccacaactt ccggcactgc ttctgcgtgg cccagatgat gtacagcatg    660

gtctggctct gcagtctcca ggagaagttc tcacaaacgg atatcctgat cctaatgaca    720

gcggccatct gccacgatct ggaccatccc ggctacaaca acacgtacca gatcaatgcc    780

cgcacagagc tggcggtccg ctacaatgac atctcaccgc tggagaacca ccactgcgcc    840

gtggccttcc agatcctcgc cgagcctgag tgcaacatct tctccaacat cccacctgat    900

gggttcaagc agatccgaca gggaatgatc acattaatct tggccactga catggcaaga    960

catgcagaaa ttatggattc tttcaaagag aaaatggaga attttgacta cagcaacgag   1020

gagcacatga ccctgctgaa gatgattttg ataaaatgct gtgatatctc taacgaggtc   1080

cgtccaatgg aagtcgcaga gccttgggtg gactgtttat tagaggaata ttttatgcag   1140

agcgaccgtg agaagtcaga aggccttcct gtggcaccgt tcatggaccg agacaaagtg   1200

accaaggcca cagcccagat tgggttcatc aagtttgtcc tgatcccaat gtttgaaaca   1260

gtgaccaagc tcttccccat ggttgaggag atcatgctgc agccactttg ggaatcccga   1320

gatcgctacg aggagctgaa gcggatagat gacgccatga aagagttaca gaagaagact   1380

gacagcttga cgtctggggc caccgagaag tccagagaga gaagcagaga tgtgaaaaac   1440

agtgaaggag actgtgcctg aggaaagcgg ggggcgtggc tgcagttctg gacgggctgg   1500

ccgagctgcg cgggatcctt gtgcagggaa gagctgccct gggcacctgg caccacaaga   1560

ccatgttttc taagaaccat tttgttcact gatacaaaaa aaaaaaaagg aattcatgat   1620

gctgtacaga attttatttt taaactgtct tttaaataat atattcttat acgg         1674


<210>  10332
<211>  465
<212>  PRT
<213>  Homo sapiens

<400>  10332

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys His Ser Val Gln Ser Glu Thr Cys Gly 
            20                  25                  30


His Gln Ala Thr Leu Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
        35                  40                  45


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
    50                  55                  60


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
65                  70                  75                  80


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
                85                  90                  95


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
            100                 105                 110


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
        115                 120                 125


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
    130                 135                 140


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
145                 150                 155                 160


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
                165                 170                 175


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
            180                 185                 190


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
        195                 200                 205


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
    210                 215                 220


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
225                 230                 235                 240


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
                245                 250                 255


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
            260                 265                 270


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
        275                 280                 285


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
    290                 295                 300


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
305                 310                 315                 320


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
                325                 330                 335


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
            340                 345                 350


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
        355                 360                 365


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
    370                 375                 380


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
385                 390                 395                 400


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
                405                 410                 415


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
            420                 425                 430


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
        435                 440                 445


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
    450                 455                 460


Ala 
465


<210>  10333
<211>  1909
<212>  DNA
<213>  Homo sapiens

<400>  10333
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agcactccgt acaaagtgag acctgtggcc atcaagcaac tctccgctgg    180

tgtcgaggac aagagaacca caagccgtgg ccagtctgct gagagaccac tgagggacag    240

acgggttgtg ggcctggagc agccccggag ggaaggagca tttgaaagtg gacaggtaga    300

gcccaggccc agagagcccc agggctgcta ccaggaaggc cagcgcatcc ctccagagag    360

agaagaatta atccagagcg tgctggcgca ggttgcagag cagttctcaa gagcattcaa    420

aatcaatgaa ctgaaagctg aagttgcaaa tcacttggct gtcctagaga aacgcgtgga    480

attggaagga ctaaaagtgg tggagattga gaaatgcaag agtgacatta agaagatgag    540

ggaggagctg gcggccagaa gcagcaggac caactgcccc tgtaagtaca gttttttgga    600

taaccacaag aagttgactc ctcgacgcga tgttcccact taccccaagt acctgctctc    660

tccagagacc atcgaggccc tgcggaagcc gacctttgac gtctggcttt gggagcccaa    720

tgagatgctg agctgcctgg agcacatgta ccacgacctc gggctggtca gggacttcag    780

catcaaccct gtcaccctca ggaggtggct gttctgcgtc cacgacaact acagaaacaa    840

ccccttccac aacttccggc actgcttctg cgtggcccag atgatgtaca gcatggtctg    900

gctctgcagt ctccaggaga agttctcaca aacggatatc ctgatcctaa tgacagcggc    960

catctgccac gatctggacc atcccggcta caacaacacg taccagatca atgcccgcac   1020

agagctggcg gtccgctaca atgacatctc accgctggag aaccaccact gcgccgtggc   1080

cttccagatc ctcgccgagc ctgagtgcaa catcttctcc aacatcccac ctgatgggtt   1140

caagcagatc cgacagggaa tgatcacatt aatcttggcc actgacatgg caagacatgc   1200

agaaattatg gattctttca aagagaaaat ggagaatttt gactacagca acgaggagca   1260

catgaccctg ctgaagatga ttttgataaa atgctgtgat atctctaacg aggtccgtcc   1320

aatggaagtc gcagagcctt gggtggactg tttattagag gaatatttta tgcagagcga   1380

ccgtgagaag tcagaaggcc ttcctgtggc accgttcatg gaccgagaca aagtgaccaa   1440

ggccacagcc cagattgggt tcatcaagtt tgtcctgatc ccaatgtttg aaacagtgac   1500

caagctcttc cccatggttg aggagatcat gctgcagcca ctttgggaat cccgagatcg   1560

ctacgaggag ctgaagcgga tagatgacgc catgaaagag ttacagaaga agactgacag   1620

cttgacgtct ggggccaccg agaagtccag agagagaagc agagatgtga aaaacagtga   1680

aggagactgt gcctgaggaa agcggggggc gtggctgcag ttctggacgg gctggccgag   1740

ctgcgcggga tccttgtgca gggaagagct gccctgggca cctggcacca caagaccatg   1800

ttttctaaga accattttgt tcactgatac aaaaaaaaaa aaaggaattc atgatgctgt   1860

acagaatttt atttttaaac tgtcttttaa ataatatatt cttatacgg               1909


<210>  10334
<211>  526
<212>  PRT
<213>  Homo sapiens

<400>  10334

Met Asp Ala Phe Arg Ser Thr Pro Tyr Lys Val Arg Pro Val Ala Ile 
1               5                   10                  15


Lys Gln Leu Ser Ala Gly Val Glu Asp Lys Arg Thr Thr Ser Arg Gly 
            20                  25                  30


Gln Ser Ala Glu Arg Pro Leu Arg Asp Arg Arg Val Val Gly Leu Glu 
        35                  40                  45


Gln Pro Arg Arg Glu Gly Ala Phe Glu Ser Gly Gln Val Glu Pro Arg 
    50                  55                  60


Pro Arg Glu Pro Gln Gly Cys Tyr Gln Glu Gly Gln Arg Ile Pro Pro 
65                  70                  75                  80


Glu Arg Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln 
                85                  90                  95


Phe Ser Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn 
            100                 105                 110


His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val 
        115                 120                 125


Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu 
    130                 135                 140


Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe 
145                 150                 155                 160


Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr 
                165                 170                 175


Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro 
            180                 185                 190


Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu 
        195                 200                 205


Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn 
    210                 215                 220


Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg 
225                 230                 235                 240


Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met 
                245                 250                 255


Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln 
            260                 265                 270


Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp 
        275                 280                 285


His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu 
    290                 295                 300


Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala 
305                 310                 315                 320


Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn 
                325                 330                 335


Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu 
            340                 345                 350


Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe 
        355                 360                 365


Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr 
    370                 375                 380


Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val 
385                 390                 395                 400


Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu 
                405                 410                 415


Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala 
            420                 425                 430


Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly 
        435                 440                 445


Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu 
    450                 455                 460


Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg 
465                 470                 475                 480


Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu 
                485                 490                 495


Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg 
            500                 505                 510


Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
        515                 520                 525


<210>  10335
<211>  2058
<212>  DNA
<213>  Homo sapiens

<400>  10335
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggtaatctt cagcaagtac tgcaactcca gcgacatcat ggacctgttc    180

tgcatcgcca ccggcctgcc tcggaacacg accatctccc tgctgaccac cgacgacgcc    240

atggtctcca tcgaccccac catgcccgcg aattcagaac gcactccgta caaagtgaga    300

cctgtggcca tcaagcaact ctccgctggt gtcgaggaca agagaaccac aagccgtggc    360

cagtctgctg agagaccact gagggacaga cgggttgtgg gcctggagca gccccggagg    420

gaaggagcat ttgaaagtgg acaggtagag cccaggccca gagagcccca gggctgctac    480

caggaaggcc agcgcatccc tccagagaga gaagaattaa tccagagcgt gctggcgcag    540

gttgcagagc agttctcaag agcattcaaa atcaatgaac tgaaagctga agttgcaaat    600

cacttggctg tcctagagaa acgcgtggaa ttggaaggac taaaagtggt ggagattgag    660

aaatgcaaga gtgacattaa gaagatgagg gaggagctgg cggccagaag cagcaggacc    720

aactgcccct gtaagtacag ttttttggat aaccacaaga agttgactcc tcgacgcgat    780

gttcccactt accccaagta cctgctctct ccagagacca tcgaggccct gcggaagccg    840

acctttgacg tctggctttg ggagcccaat gagatgctga gctgcctgga gcacatgtac    900

cacgacctcg ggctggtcag ggacttcagc atcaaccctg tcaccctcag gaggtggctg    960

ttctgcgtcc acgacaacta cagaaacaac cccttccaca acttccggca ctgcttctgc   1020

gtggcccaga tgatgtacag catggtctgg ctctgcagtc tccaggagaa gttctcacaa   1080

acggatatcc tgatcctaat gacagcggcc atctgccacg atctggacca tcccggctac   1140

aacaacacgt accagatcaa tgcccgcaca gagctggcgg tccgctacaa tgacatctca   1200

ccgctggaga accaccactg cgccgtggcc ttccagatcc tcgccgagcc tgagtgcaac   1260

atcttctcca acatcccacc tgatgggttc aagcagatcc gacagggaat gatcacatta   1320

atcttggcca ctgacatggc aagacatgca gaaattatgg attctttcaa agagaaaatg   1380

gagaattttg actacagcaa cgaggagcac atgaccctgc tgaagatgat tttgataaaa   1440

tgctgtgata tctctaacga ggtccgtcca atggaagtcg cagagccttg ggtggactgt   1500

ttattagagg aatattttat gcagagcgac cgtgagaagt cagaaggcct tcctgtggca   1560

ccgttcatgg accgagacaa agtgaccaag gccacagccc agattgggtt catcaagttt   1620

gtcctgatcc caatgtttga aacagtgacc aagctcttcc ccatggttga ggagatcatg   1680

ctgcagccac tttgggaatc ccgagatcgc tacgaggagc tgaagcggat agatgacgcc   1740

atgaaagagt tacagaagaa gactgacagc ttgacgtctg gggccaccga gaagtccaga   1800

gagagaagca gagatgtgaa aaacagtgaa ggagactgtg cctgaggaaa gcggggggcg   1860

tggctgcagt tctggacggg ctggccgagc tgcgcgggat ccttgtgcag ggaagagctg   1920

ccctgggcac ctggcaccac aagaccatgt tttctaagaa ccattttgtt cactgataca   1980

aaaaaaaaaa aaggaattca tgatgctgta cagaatttta tttttaaact gtcttttaaa   2040

taatatattc ttatacgg                                                 2058


<210>  10336
<211>  593
<212>  PRT
<213>  Homo sapiens

<400>  10336

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Ala Gly Val Glu Asp Lys Arg Thr Thr 
                85                  90                  95


Ser Arg Gly Gln Ser Ala Glu Arg Pro Leu Arg Asp Arg Arg Val Val 
            100                 105                 110


Gly Leu Glu Gln Pro Arg Arg Glu Gly Ala Phe Glu Ser Gly Gln Val 
        115                 120                 125


Glu Pro Arg Pro Arg Glu Pro Gln Gly Cys Tyr Gln Glu Gly Gln Arg 
    130                 135                 140


Ile Pro Pro Glu Arg Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val 
145                 150                 155                 160


Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
                165                 170                 175


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
            180                 185                 190


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
        195                 200                 205


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
    210                 215                 220


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
225                 230                 235                 240


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
                245                 250                 255


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
            260                 265                 270


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
        275                 280                 285


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
    290                 295                 300


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
305                 310                 315                 320


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
                325                 330                 335


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
            340                 345                 350


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
        355                 360                 365


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
    370                 375                 380


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
385                 390                 395                 400


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
                405                 410                 415


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
            420                 425                 430


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
        435                 440                 445


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
    450                 455                 460


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
465                 470                 475                 480


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
                485                 490                 495


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
            500                 505                 510


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
        515                 520                 525


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
    530                 535                 540


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
545                 550                 555                 560


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
                565                 570                 575


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
            580                 585                 590


Ala 



<210>  10337
<211>  1800
<212>  DNA
<213>  Homo sapiens

<400>  10337
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggtaatctt cagcaagtac tgcaactcca gcgacatcat ggacctgttc    180

tgcatcgcca ccggcctgcc tcgcactccg tacaaagtga gacctgtggc catcaagcaa    240

ctctccgaga gagaagaatt aatccagagc gtgctggcgc aggttgcaga gcagttctca    300

agagcattca aaatcaatga actgaaagct gaagttgcaa atcacttggc tgtcctagag    360

aaacgcgtgg aattggaagg actaaaagtg gtggagattg agaaatgcaa gagtgacatt    420

aagaagatga gggaggagct ggcggccaga agcagcagga ccaactgccc ctgtaagtac    480

agttttttgg ataaccacaa gaagttgact cctcgacgcg atgttcccac ttaccccaag    540

tacctgctct ctccagagac catcgaggcc ctgcggaagc cgacctttga cgtctggctt    600

tgggagccca atgagatgct gagctgcctg gagcacatgt accacgacct cgggctggtc    660

agggacttca gcatcaaccc tgtcaccctc aggaggtggc tgttctgcgt ccacgacaac    720

tacagaaaca accccttcca caacttccgg cactgcttct gcgtggccca gatgatgtac    780

agcatggtct ggctctgcag tctccaggag aagttctcac aaacggatat cctgatccta    840

atgacagcgg ccatctgcca cgatctggac catcccggct acaacaacac gtaccagatc    900

aatgcccgca cagagctggc ggtccgctac aatgacatct caccgctgga gaaccaccac    960

tgcgccgtgg ccttccagat cctcgccgag cctgagtgca acatcttctc caacatccca   1020

cctgatgggt tcaagcagat ccgacaggga atgatcacat taatcttggc cactgacatg   1080

gcaagacatg cagaaattat ggattctttc aaagagaaaa tggagaattt tgactacagc   1140

aacgaggagc acatgaccct gctgaagatg attttgataa aatgctgtga tatctctaac   1200

gaggtccgtc caatggaagt cgcagagcct tgggtggact gtttattaga ggaatatttt   1260

atgcagagcg accgtgagaa gtcagaaggc cttcctgtgg caccgttcat ggaccgagac   1320

aaagtgacca aggccacagc ccagattggg ttcatcaagt ttgtcctgat cccaatgttt   1380

gaaacagtga ccaagctctt ccccatggtt gaggagatca tgctgcagcc actttgggaa   1440

tcccgagatc gctacgagga gctgaagcgg atagatgacg ccatgaaaga gttacagaag   1500

aagactgaca gcttgacgtc tggggccacc gagaagtcca gagagagaag cagagatgtg   1560

aaaaacagtg aaggagactg tgcctgagga aagcgggggg cgtggctgca gttctggacg   1620

ggctggccga gctgcgcggg atccttgtgc agggaagagc tgccctgggc acctggcacc   1680

acaagaccat gttttctaag aaccattttg ttcactgata caaaaaaaaa aaaaggaatt   1740

catgatgctg tacagaattt tatttttaaa ctgtctttta aataatatat tcttatacgg   1800


<210>  10338
<211>  507
<212>  PRT
<213>  Homo sapiens

<400>  10338

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Thr 
        35                  40                  45


Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Glu Arg Glu 
    50                  55                  60


Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg 
65                  70                  75                  80


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
                85                  90                  95


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
            100                 105                 110


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
        115                 120                 125


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
    130                 135                 140


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
145                 150                 155                 160


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
                165                 170                 175


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
            180                 185                 190


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
        195                 200                 205


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
    210                 215                 220


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
225                 230                 235                 240


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
                245                 250                 255


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
            260                 265                 270


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
        275                 280                 285


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
    290                 295                 300


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
305                 310                 315                 320


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
                325                 330                 335


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
            340                 345                 350


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
        355                 360                 365


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
    370                 375                 380


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
385                 390                 395                 400


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
                405                 410                 415


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
            420                 425                 430


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
        435                 440                 445


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
    450                 455                 460


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
465                 470                 475                 480


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
                485                 490                 495


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
            500                 505


<210>  10339
<211>  1932
<212>  DNA
<213>  Homo sapiens

<400>  10339
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggaacacga ccatctccct gctgaccacc gacgacgcca tggtctccat    180

cgaccccacc atgcccgcga attcagaacg cactccgtac aaagtgagac ctgtggccat    240

caagcaactc tccgctggtg tcgaggacaa gagaaccaca agccgtggcc agtctgctga    300

gagaccactg agggacagac gggttgtggg cctggagcag ccccggaggg aaggagcatt    360

tgaaagtgga caggtagagc ccaggcccag agagccccag ggctgctacc aggaaggcca    420

gcgcatccct ccagagcatt caaaatcaat gaactgaaag ctgaagttgc aaatcacttg    480

gctgtcctag agaaacgcgt ggaattggaa ggactaaaag tggtggagat tgagaaatgc    540

aagagtgaca ttaagaagat gagggaggag ctggcggcca gaagcagcag gaccaactgc    600

ccctgtaagt acagtttttt ggataaccac aagaagttga ctcctcgacg cgatgttccc    660

acttacccca agtacctgct ctctccagag accatcgagg ccctgcggaa gccgaccttt    720

gacgtctggc tttgggagcc caatgagatg ctgagctgcc tggagcacat gtaccacgac    780

ctcgggctgg tcagggactt cagcatcaac cctgtcaccc tcaggaggtg gctgttctgc    840

gtccacgaca actacagaaa caaccccttc cacaacttcc ggcactgctt ctgcgtggcc    900

cagatgatgt acagcatggt ctggctctgc agtctccagg agaagttctc acaaacggat    960

atcctgatcc taatgacagc ggccatctgc cacgatctgg accatcccgg ctacaacaac   1020

acgtaccaga tcaatgcccg cacagagctg gcggtccgct acaatgacat ctcaccgctg   1080

gagaaccacc actgcgccgt ggccttccag atcctcgccg agcctgagtg caacatcttc   1140

tccaacatcc cacctgatgg gttcaagcag atccgacagg gaatgatcac attaatcttg   1200

gccactgaca tggcaagaca tgcagaaatt atggattctt tcaaagagaa aatggagaat   1260

tttgactaca gcaacgagga gcacatgacc ctgctgaaga tgattttgat aaaatgctgt   1320

gatatctcta acgaggtccg tccaatggaa gtcgcagagc cttgggtgga ctgtttatta   1380

gaggaatatt ttatgcagag cgaccgtgag aagtcagaag gccttcctgt ggcaccgttc   1440

atggaccgag acaaagtgac caaggccaca gcccagattg ggttcatcaa gtttgtcctg   1500

atcccaatgt ttgaaacagt gaccaagctc ttccccatgg ttgaggagat catgctgcag   1560

ccactttggg aatcccgaga tcgctacgag gagctgaagc ggatagatga cgccatgaaa   1620

gagttacaga agaagactga cagcttgacg tctggggcca ccgagaagtc cagagagaga   1680

agcagagatg tgaaaaacag tgaaggagac tgtgcctgag gaaagcgggg ggcgtggctg   1740

cagttctgga cgggctggcc gagctgcgcg ggatccttgt gcagggaaga gctgccctgg   1800

gcacctggca ccacaagacc atgttttcta agaaccattt tgttcactga tacaaaaaaa   1860

aaaaaaggaa ttcatgatgc tgtacagaat tttattttta aactgtcttt taaataatat   1920

attcttatac gg                                                       1932


<210>  10340
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10340

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10341
<211>  1708
<212>  DNA
<213>  Homo sapiens

<400>  10341
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggaacacga ccatctccct gctgaccacc gacgacgcca tggtctccat    180

cgaccccacc atgcccgcga attcagaacg agcattcaaa atcaatgaac tgaaagctga    240

agttgcaaat cacttggctg tcctagagaa acgcgtggaa ttggaaggac taaaagtggt    300

ggagattgag aaatgcaaga gtgacattaa gaagatgagg gaggagctgg cggccagaag    360

cagcaggacc aactgcccct gtaagtacag ttttttggat aaccacaaga agttgactcc    420

tcgacgcgat gttcccactt accccaagta cctgctctct ccagagacca tcgaggccct    480

gcggaagccg acctttgacg tctggctttg ggagcccaat gagatgctga gctgcctgga    540

gcacatgtac cacgacctcg ggctggtcag ggacttcagc atcaaccctg tcaccctcag    600

gaggtggctg ttctgcgtcc acgacaacta cagaaacaac cccttccaca acttccggca    660

ctgcttctgc gtggcccaga tgatgtacag catggtctgg ctctgcagtc tccaggagaa    720

gttctcacaa acggatatcc tgatcctaat gacagcggcc atctgccacg atctggacca    780

tcccggctac aacaacacgt accagatcaa tgcccgcaca gagctggcgg tccgctacaa    840

tgacatctca ccgctggaga accaccactg cgccgtggcc ttccagatcc tcgccgagcc    900

tgagtgcaac atcttctcca acatcccacc tgatgggttc aagcagatcc gacagggaat    960

gatcacatta atcttggcca ctgacatggc aagacatgca gaaattatgg attctttcaa   1020

agagaaaatg gagaattttg actacagcaa cgaggagcac atgaccctgc tgaagatgat   1080

tttgataaaa tgctgtgata tctctaacga ggtccgtcca atggaagtcg cagagccttg   1140

ggtggactgt ttattagagg aatattttat gcagagcgac cgtgagaagt cagaaggcct   1200

tcctgtggca ccgttcatgg accgagacaa agtgaccaag gccacagccc agattgggtt   1260

catcaagttt gtcctgatcc caatgtttga aacagtgacc aagctcttcc ccatggttga   1320

ggagatcatg ctgcagccac tttgggaatc ccgagatcgc tacgaggagc tgaagcggat   1380

agatgacgcc atgaaagagt tacagaagaa gactgacagc ttgacgtctg gggccaccga   1440

gaagtccaga gagagaagca gagatgtgaa aaacagtgaa ggagactgtg cctgaggaaa   1500

gcggggggcg tggctgcagt tctggacggg ctggccgagc tgcgcgggat ccttgtgcag   1560

ggaagagctg ccctgggcac ctggcaccac aagaccatgt tttctaagaa ccattttgtt   1620

cactgataca aaaaaaaaaa aaggaattca tgatgctgta cagaatttta tttttaaact   1680

gtcttttaaa taatatattc ttatacgg                                      1708


<210>  10342
<211>  459
<212>  PRT
<213>  Homo sapiens

<400>  10342

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
        35                  40                  45


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
    50                  55                  60


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
65                  70                  75                  80


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
                85                  90                  95


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
            100                 105                 110


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
        115                 120                 125


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
    130                 135                 140


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
145                 150                 155                 160


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
                165                 170                 175


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
            180                 185                 190


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
        195                 200                 205


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
    210                 215                 220


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
225                 230                 235                 240


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
                245                 250                 255


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
            260                 265                 270


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
        275                 280                 285


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
    290                 295                 300


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
305                 310                 315                 320


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
                325                 330                 335


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
            340                 345                 350


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
        355                 360                 365


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
    370                 375                 380


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
385                 390                 395                 400


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
                405                 410                 415


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
            420                 425                 430


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
        435                 440                 445


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
    450                 455


<210>  10343
<211>  1545
<212>  DNA
<213>  Homo sapiens

<400>  10343
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agagcattca aaatcaatga actgaaagct gaagttgcaa atcacttggc    180

tgtcctagag aaacgcgtgg aatgaccaac tgcccctgta agtacagttt tttggataac    240

cacaagaagt tgactcctcg acgcgatgtt cccacttacc ccaagtacct gctctctcca    300

gagaccatcg aggccctgcg gaagccgacc tttgacgtct ggctttggga gcccaatgag    360

atgctgagct gcctggagca catgtaccac gacctcgggc tggtcaggga cttcagcatc    420

aaccctgtca ccctcaggag gtggctgttc tgcgtccacg acaactacag aaacaacccc    480

ttccacaact tccggcactg cttctgcgtg gcccagatga tgtacagcat ggtctggctc    540

tgcagtctcc aggagaagtt ctcacaaacg gatatcctga tcctaatgac agcggccatc    600

tgccacgatc tggaccatcc cggctacaac aacacgtacc agatcaatgc ccgcacagag    660

ctggcggtcc gctacaatga catctcaccg ctggagaacc accactgcgc cgtggccttc    720

cagatcctcg ccgagcctga gtgcaacatc ttctccaaca tcccacctga tgggttcaag    780

cagatccgac agggaatgat cacattaatc ttggccactg acatggcaag acatgcagaa    840

attatggatt ctttcaaaga gaaaatggag aattttgact acagcaacga ggagcacatg    900

accctgctga agatgatttt gataaaatgc tgtgatatct ctaacgaggt ccgtccaatg    960

gaagtcgcag agccttgggt ggactgttta ttagaggaat attttatgca gagcgaccgt   1020

gagaagtcag aaggccttcc tgtggcaccg ttcatggacc gagacaaagt gaccaaggcc   1080

acagcccaga ttgggttcat caagtttgtc ctgatcccaa tgtttgaaac agtgaccaag   1140

ctcttcccca tggttgagga gatcatgctg cagccacttt gggaatcccg agatcgctac   1200

gaggagctga agcggataga tgacgccatg aaagagttac agaagaagac tgacagcttg   1260

acgtctgggg ccaccgagaa gtccagagag agaagcagag atgtgaaaaa cagtgaagga   1320

gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct ggacgggctg gccgagctgc   1380

gcgggatcct tgtgcaggga agagctgccc tgggcacctg gcaccacaag accatgtttt   1440

ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag gaattcatga tgctgtacag   1500

aattttattt ttaaactgtc ttttaaataa tatattctta tacgg                   1545


<210>  10344
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  10344

Met Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
1               5                   10                  15


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
            20                  25                  30


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
        35                  40                  45


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
    50                  55                  60


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
65                  70                  75                  80


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
                85                  90                  95


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
            100                 105                 110


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
        115                 120                 125


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
    130                 135                 140


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
145                 150                 155                 160


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
                165                 170                 175


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
            180                 185                 190


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
        195                 200                 205


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
    210                 215                 220


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
225                 230                 235                 240


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
                245                 250                 255


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
            260                 265                 270


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
        275                 280                 285


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
    290                 295                 300


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
305                 310                 315                 320


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
                325                 330                 335


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
            340                 345                 350


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
        355                 360                 365


Lys Asn Ser Glu Gly Asp Cys Ala 
    370                 375


<210>  10345
<211>  1987
<212>  DNA
<213>  Homo sapiens

<400>  10345
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggaacacga ccatctccct gctgaccacc gacgacgcca tggtctccat    180

cgaccccacc atgcccgcga attcagaacg cactccgtac aaagtgagac ctgtggccat    240

caagcaactc tccgctggtg tcgaggacaa gagaaccaca agccgtggcc agtctgctga    300

gagaccactg agggacagac gggttgtggg cctggagcag ccccggaggg aaggagcatt    360

tgaaagtgga caggtagagc ccaggcccag agagccccag ggctgctacc aggaaggcca    420

gcgcatccct ccagagagag aagaattaat ccagagcgtg ctggcgcagg ttgcagagca    480

gttctcaaga gcattcaaaa tcaatgaact gaaagctgaa gttgcaaatc acttggctgt    540

cctagagaaa cgcgtggaat tggaaggact aaaagtggtg gagattgaga aatgcaagag    600

tgacattaag aagatgaggg aggagctggc ggccagaagc agcaggacca actgcccctg    660

taagtacagt tttttggata accacaagaa gttgactcct cgacgcgatg ttcccactta    720

ccccaagtac ctgctctctc cagagaccat cgaggccctg cggaagccga cctttgacgt    780

ctggctttgg gagcccaatg agatgctgag ctgcctggag cacatgtacc acgacctcgg    840

gctggtcagg gacttcagca tcaaccctgt caccctcagg aggtggctgt tctgcgtcca    900

cgacaactac agaaacaacc ccttccacaa cttccggcac tgcttctgcg tggcccagat    960

gatgtacagc atggtctggc tctgcagtct ccaggagaag ttctcacaaa cggatatcct   1020

gatcctaatg acagcggcca tctgccacga tctggaccat cccggctaca acaacacgta   1080

ccagatcaat gcccgcacag agctggcggt ccgctacaat gacatctcac cgctggagaa   1140

ccaccactgc gccgtggcct tccagatcct cgccgagcct gagtgcaaca tcttctccaa   1200

catcccacct gatgggttca agcagatccg acagggaatg atcacattaa tcttggccac   1260

tgacatggca agacatgcag aaattatgga ttctttcaaa gagaaaatgg agaattttga   1320

ctacagcaac gaggagcaca tgaccctgct gaagatgatt ttgataaaat gctgtgatat   1380

ctctaacgag gtccgtccaa tggaagtcgc agagccttgg gtggactgtt tattagagga   1440

atattttatg cagagcgacc gtgagaagtc agaaggcctt cctgtggcac cgttcatgga   1500

ccgagacaaa gtgaccaagg ccacagccca gattgggttc atcaagtttg tcctgatccc   1560

aatgtttgaa acagtgacca agctcttccc catggttgag gagatcatgc tgcagccact   1620

ttgggaatcc cgagatcgct acgaggagct gaagcggata gatgacgcca tgaaagagtt   1680

acagaagaag actgacagct tgacgtctgg ggccaccgag aagtccagag agagaagcag   1740

agatgtgaaa aacagtgaag gagactgtgc ctgaggaaag cggggggcgt ggctgcagtt   1800

ctggacgggc tggccgagct gcgcgggatc cttgtgcagg gaagagctgc cctgggcacc   1860

tggcaccaca agaccatgtt ttctaagaac cattttgttc actgatacaa aaaaaaaaaa   1920

aggaattcat gatgctgtac agaattttat ttttaaactg tcttttaaat aatatattct   1980

tatacgg                                                             1987


<210>  10346
<211>  552
<212>  PRT
<213>  Homo sapiens

<400>  10346

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Thr Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Ala Gly 
        35                  40                  45


Val Glu Asp Lys Arg Thr Thr Ser Arg Gly Gln Ser Ala Glu Arg Pro 
    50                  55                  60


Leu Arg Asp Arg Arg Val Val Gly Leu Glu Gln Pro Arg Arg Glu Gly 
65                  70                  75                  80


Ala Phe Glu Ser Gly Gln Val Glu Pro Arg Pro Arg Glu Pro Gln Gly 
                85                  90                  95


Cys Tyr Gln Glu Gly Gln Arg Ile Pro Pro Glu Arg Glu Glu Leu Ile 
            100                 105                 110


Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys 
        115                 120                 125


Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu 
    130                 135                 140


Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys 
145                 150                 155                 160


Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser 
                165                 170                 175


Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
            180                 185                 190


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
        195                 200                 205


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
    210                 215                 220


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
225                 230                 235                 240


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
                245                 250                 255


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
            260                 265                 270


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
        275                 280                 285


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
    290                 295                 300


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
305                 310                 315                 320


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
                325                 330                 335


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
            340                 345                 350


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
        355                 360                 365


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
    370                 375                 380


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
385                 390                 395                 400


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
                405                 410                 415


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
            420                 425                 430


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
        435                 440                 445


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
    450                 455                 460


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
465                 470                 475                 480


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
                485                 490                 495


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
            500                 505                 510


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
        515                 520                 525


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
    530                 535                 540


Lys Asn Ser Glu Gly Asp Cys Ala 
545                 550


<210>  10347
<211>  1980
<212>  DNA
<213>  Homo sapiens

<400>  10347
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggtaatctt cagcaagtac tgcaactcca gcgacatcat ggacctgttc    180

tgcatcgcca ccggcctgcc tcgcactccg tacaaagtga gacctgtggc catcaagcaa    240

ctctccgctg gtgtcgagga caagagaacc acaagccgtg gccagtctgc tgagagacca    300

ctgagggaca gacgggttgt gggcctggag cagccccgga gggaaggagc atttgaaagt    360

ggacaggtag agcccaggcc cagagagccc cagggctgct accaggaagg ccagcgcatc    420

cctccagaga gagaagaatt aatccagagc gtgctggcgc aggttgcaga gcagttctca    480

agagcattca aaatcaatga actgaaagct gaagttgcaa atcacttggc tgtcctagag    540

aaacgcgtgg aattggaagg actaaaagtg gtggagattg agaaatgcaa gagtgacatt    600

aagaagatga gggaggagct ggcggccaga agcagcagga ccaactgccc ctgtaagtac    660

agttttttgg ataaccacaa gaagttgact cctcgacgcg atgttcccac ttaccccaag    720

tacctgctct ctccagagac catcgaggcc ctgcggaagc cgacctttga cgtctggctt    780

tgggagccca atgagatgct gagctgcctg gagcacatgt accacgacct cgggctggtc    840

agggacttca gcatcaaccc tgtcaccctc aggaggtggc tgttctgcgt ccacgacaac    900

tacagaaaca accccttcca caacttccgg cactgcttct gcgtggccca gatgatgtac    960

agcatggtct ggctctgcag tctccaggag aagttctcac aaacggatat cctgatccta   1020

atgacagcgg ccatctgcca cgatctggac catcccggct acaacaacac gtaccagatc   1080

aatgcccgca cagagctggc ggtccgctac aatgacatct caccgctgga gaaccaccac   1140

tgcgccgtgg ccttccagat cctcgccgag cctgagtgca acatcttctc caacatccca   1200

cctgatgggt tcaagcagat ccgacaggga atgatcacat taatcttggc cactgacatg   1260

gcaagacatg cagaaattat ggattctttc aaagagaaaa tggagaattt tgactacagc   1320

aacgaggagc acatgaccct gctgaagatg attttgataa aatgctgtga tatctctaac   1380

gaggtccgtc caatggaagt cgcagagcct tgggtggact gtttattaga ggaatatttt   1440

atgcagagcg accgtgagaa gtcagaaggc cttcctgtgg caccgttcat ggaccgagac   1500

aaagtgacca aggccacagc ccagattggg ttcatcaagt ttgtcctgat cccaatgttt   1560

gaaacagtga ccaagctctt ccccatggtt gaggagatca tgctgcagcc actttgggaa   1620

tcccgagatc gctacgagga gctgaagcgg atagatgacg ccatgaaaga gttacagaag   1680

aagactgaca gcttgacgtc tggggccacc gagaagtcca gagagagaag cagagatgtg   1740

aaaaacagtg aaggagactg tgcctgagga aagcgggggg cgtggctgca gttctggacg   1800

ggctggccga gctgcgcggg atccttgtgc agggaagagc tgccctgggc acctggcacc   1860

acaagaccat gttttctaag aaccattttg ttcactgata caaaaaaaaa aaaaggaatt   1920

catgatgctg tacagaattt tatttttaaa ctgtctttta aataatatat tcttatacgg   1980


<210>  10348
<211>  567
<212>  PRT
<213>  Homo sapiens

<400>  10348

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Thr 
        35                  40                  45


Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Ala Gly Val 
    50                  55                  60


Glu Asp Lys Arg Thr Thr Ser Arg Gly Gln Ser Ala Glu Arg Pro Leu 
65                  70                  75                  80


Arg Asp Arg Arg Val Val Gly Leu Glu Gln Pro Arg Arg Glu Gly Ala 
                85                  90                  95


Phe Glu Ser Gly Gln Val Glu Pro Arg Pro Arg Glu Pro Gln Gly Cys 
            100                 105                 110


Tyr Gln Glu Gly Gln Arg Ile Pro Pro Glu Arg Glu Glu Leu Ile Gln 
        115                 120                 125


Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile 
    130                 135                 140


Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu Lys 
145                 150                 155                 160


Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys 
                165                 170                 175


Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg 
            180                 185                 190


Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu 
        195                 200                 205


Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro 
    210                 215                 220


Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp 
225                 230                 235                 240


Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp Leu 
                245                 250                 255


Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp 
            260                 265                 270


Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe 
        275                 280                 285


Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp Leu 
    290                 295                 300


Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met 
305                 310                 315                 320


Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr 
                325                 330                 335


Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile 
            340                 345                 350


Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu Ala 
        355                 360                 365


Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys 
    370                 375                 380


Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala 
385                 390                 395                 400


Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe 
                405                 410                 415


Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu Ile 
            420                 425                 430


Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu 
        435                 440                 445


Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg 
    450                 455                 460


Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys 
465                 470                 475                 480


Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile 
                485                 490                 495


Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile 
            500                 505                 510


Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys 
        515                 520                 525


Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu 
    530                 535                 540


Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys 
545                 550                 555                 560


Asn Ser Glu Gly Asp Cys Ala 
                565


<210>  10349
<211>  1685
<212>  DNA
<213>  Homo sapiens

<400>  10349
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agagagagaa gaattaatcc agagcgtgct ggcgcaggtt gcagagcagt    180

tctcaagagc attcaaaatc aatgaactga aagctgaagt tgcaaatcac ttggctgtcc    240

tagagaaacg cgtggaattg gaaggactaa aagtggtgga gattgagaaa tgcaagagtg    300

acattaagaa gatgagggag gagctggcgg ccagaagcag caggaccaac tgcccctgta    360

agtacagttt tttggataac cacaagaagt tgactcctcg acgcgatgtt cccacttacc    420

ccaagtacct gctctctcca gagaccatcg aggccctgcg gaagccgacc tttgacgtct    480

ggctttggga gcccaatgag atgctgagct gcctggagca catgtaccac gacctcgggc    540

tggtcaggga cttcagcatc aaccctgtca ccctcaggag gtggctgttc tgcgtccacg    600

acaactacag aaacaacccc ttccacaact tccggcactg cttctgcgtg gcccagatga    660

tgtacagcat ggtctggctc tgcagtctcc aggagaagtt ctcacaaacg gatatcctga    720

tcctaatgac agcggccatc tgccacgatc tggaccatcc cggctacaac aacacgtacc    780

agatcaatgc ccgcacagag ctggcggtcc gctacaatga catctcaccg ctggagaacc    840

accactgcgc cgtggccttc cagatcctcg ccgagcctga gtgcaacatc ttctccaaca    900

tcccacctga tgggttcaag cagatccgac agggaatgat cacattaatc ttggccactg    960

acatggcaag acatgcagaa attatggatt ctttcaaaga gaaaatggag aattttgact   1020

acagcaacga ggagcacatg accctgctga agatgatttt gataaaatgc tgtgatatct   1080

ctaacgaggt ccgtccaatg gaagtcgcag agccttgggt ggactgttta ttagaggaat   1140

attttatgca gagcgaccgt gagaagtcag aaggccttcc tgtggcaccg ttcatggacc   1200

gagacaaagt gaccaaggcc acagcccaga ttgggttcat caagtttgtc ctgatcccaa   1260

tgtttgaaac agtgaccaag ctcttcccca tggttgagga gatcatgctg cagccacttt   1320

gggaatcccg agatcgctac gaggagctga agcggataga tgacgccatg aaagagttac   1380

agaagaagac tgacagcttg acgtctgggg ccaccgagaa gtccagagag agaagcagag   1440

atgtgaaaaa cagtgaagga gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct   1500

ggacgggctg gccgagctgc gcgggatcct tgtgcaggga agagctgccc tgggcacctg   1560

gcaccacaag accatgtttt ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag   1620

gaattcatga tgctgtacag aattttattt ttaaactgtc ttttaaataa tatattctta   1680

tacgg                                                               1685


<210>  10350
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10350

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10351
<211>  1589
<212>  DNA
<213>  Homo sapiens

<400>  10351
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga agcactccgt acaaagtgag acctgtggcc atcaagcaac tctccgagca    180

ttcaaaatca atgaactgaa agctgaagtt gcaaatcact tggctgtcct agagaaacgc    240

gtggaatgac caactgcccc tgtaagtaca gttttttgga taaccacaag aagttgactc    300

ctcgacgcga tgttcccact taccccaagt acctgctctc tccagagacc atcgaggccc    360

tgcggaagcc gacctttgac gtctggcttt gggagcccaa tgagatgctg agctgcctgg    420

agcacatgta ccacgacctc gggctggtca gggacttcag catcaaccct gtcaccctca    480

ggaggtggct gttctgcgtc cacgacaact acagaaacaa ccccttccac aacttccggc    540

actgcttctg cgtggcccag atgatgtaca gcatggtctg gctctgcagt ctccaggaga    600

agttctcaca aacggatatc ctgatcctaa tgacagcggc catctgccac gatctggacc    660

atcccggcta caacaacacg taccagatca atgcccgcac agagctggcg gtccgctaca    720

atgacatctc accgctggag aaccaccact gcgccgtggc cttccagatc ctcgccgagc    780

ctgagtgcaa catcttctcc aacatcccac ctgatgggtt caagcagatc cgacagggaa    840

tgatcacatt aatcttggcc actgacatgg caagacatgc agaaattatg gattctttca    900

aagagaaaat ggagaatttt gactacagca acgaggagca catgaccctg ctgaagatga    960

ttttgataaa atgctgtgat atctctaacg aggtccgtcc aatggaagtc gcagagcctt   1020

gggtggactg tttattagag gaatatttta tgcagagcga ccgtgagaag tcagaaggcc   1080

ttcctgtggc accgttcatg gaccgagaca aagtgaccaa ggccacagcc cagattgggt   1140

tcatcaagtt tgtcctgatc ccaatgtttg aaacagtgac caagctcttc cccatggttg   1200

aggagatcat gctgcagcca ctttgggaat cccgagatcg ctacgaggag ctgaagcgga   1260

tagatgacgc catgaaagag ttacagaaga agactgacag cttgacgtct ggggccaccg   1320

agaagtccag agagagaagc agagatgtga aaaacagtga aggagactgt gcctgaggaa   1380

agcggggggc gtggctgcag ttctggacgg gctggccgag ctgcgcggga tccttgtgca   1440

gggaagagct gccctgggca cctggcacca caagaccatg ttttctaaga accattttgt   1500

tcactgatac aaaaaaaaaa aaaggaattc atgatgctgt acagaatttt atttttaaac   1560

tgtcttttaa ataatatatt cttatacgg                                     1589


<210>  10352
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  10352

Met Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
1               5                   10                  15


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
            20                  25                  30


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
        35                  40                  45


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
    50                  55                  60


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
65                  70                  75                  80


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
                85                  90                  95


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
            100                 105                 110


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
        115                 120                 125


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
    130                 135                 140


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
145                 150                 155                 160


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
                165                 170                 175


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
            180                 185                 190


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
        195                 200                 205


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
    210                 215                 220


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
225                 230                 235                 240


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
                245                 250                 255


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
            260                 265                 270


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
        275                 280                 285


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
    290                 295                 300


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
305                 310                 315                 320


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
                325                 330                 335


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
            340                 345                 350


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
        355                 360                 365


Lys Asn Ser Glu Gly Asp Cys Ala 
    370                 375


<210>  10353
<211>  1807
<212>  DNA
<213>  Homo sapiens

<400>  10353
tcccgcggcg gctggcgtcg ggaaagtaca gtaaaaagtc cgagtgcagc cgccgggcgc     60

aggatgggat ccggctcctc cagctaccgg cccaaggcca tctacctgga catcgatgga    120

cgcattcaga aggaacacga ccatctccct gctgaccacc gacgacgcca tggtctccat    180

cgaccccacc atgcccgcga attcagaacg cactccgtac aaagtgagac ctgtggccat    240

caagcaactc tccgagagag aagaattaat ccagagcgtg ctggcgcagg ttgcagagca    300

gttctcaaga gcattcaaaa tcaatgaact gaaagctgaa gttgcaaatc acttggctgt    360

cctagagaaa cgcgtggaat tggaaggact aaaagtggtg gagattgaga aatgcaagag    420

tgacattaag aagatgaggg aggagctggc ggccagaagc agcaggacca actgcccctg    480

taagtacagt tttttggata accacaagaa gttgactcct cgacgcgatg ttcccactta    540

ccccaagtac ctgctctctc cagagaccat cgaggccctg cggaagccga cctttgacgt    600

ctggctttgg gagcccaatg agatgctgag ctgcctggag cacatgtacc acgacctcgg    660

gctggtcagg gacttcagca tcaaccctgt caccctcagg aggtggctgt tctgcgtcca    720

cgacaactac agaaacaacc ccttccacaa cttccggcac tgcttctgcg tggcccagat    780

gatgtacagc atggtctggc tctgcagtct ccaggagaag ttctcacaaa cggatatcct    840

gatcctaatg acagcggcca tctgccacga tctggaccat cccggctaca acaacacgta    900

ccagatcaat gcccgcacag agctggcggt ccgctacaat gacatctcac cgctggagaa    960

ccaccactgc gccgtggcct tccagatcct cgccgagcct gagtgcaaca tcttctccaa   1020

catcccacct gatgggttca agcagatccg acagggaatg atcacattaa tcttggccac   1080

tgacatggca agacatgcag aaattatgga ttctttcaaa gagaaaatgg agaattttga   1140

ctacagcaac gaggagcaca tgaccctgct gaagatgatt ttgataaaat gctgtgatat   1200

ctctaacgag gtccgtccaa tggaagtcgc agagccttgg gtggactgtt tattagagga   1260

atattttatg cagagcgacc gtgagaagtc agaaggcctt cctgtggcac cgttcatgga   1320

ccgagacaaa gtgaccaagg ccacagccca gattgggttc atcaagtttg tcctgatccc   1380

aatgtttgaa acagtgacca agctcttccc catggttgag gagatcatgc tgcagccact   1440

ttgggaatcc cgagatcgct acgaggagct gaagcggata gatgacgcca tgaaagagtt   1500

acagaagaag actgacagct tgacgtctgg ggccaccgag aagtccagag agagaagcag   1560

agatgtgaaa aacagtgaag gagactgtgc ctgaggaaag cggggggcgt ggctgcagtt   1620

ctggacgggc tggccgagct gcgcgggatc cttgtgcagg gaagagctgc cctgggcacc   1680

tggcaccaca agaccatgtt ttctaagaac cattttgttc actgatacaa aaaaaaaaaa   1740

aggaattcat gatgctgtac agaattttat ttttaaactg tcttttaaat aatatattct   1800

tatacgg                                                             1807


<210>  10354
<211>  492
<212>  PRT
<213>  Homo sapiens

<400>  10354

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Thr Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Glu Arg 
        35                  40                  45


Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser 
    50                  55                  60


Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu 
65                  70                  75                  80


Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu 
                85                  90                  95


Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala 
            100                 105                 110


Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp 
        115                 120                 125


Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys 
    130                 135                 140


Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe 
145                 150                 155                 160


Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His 
                165                 170                 175


Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val 
            180                 185                 190


Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn 
        195                 200                 205


Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr 
    210                 215                 220


Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp 
225                 230                 235                 240


Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro 
                245                 250                 255


Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val 
            260                 265                 270


Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala 
        275                 280                 285


Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro 
    290                 295                 300


Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu 
305                 310                 315                 320


Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu 
                325                 330                 335


Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu 
            340                 345                 350


Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro 
        355                 360                 365


Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe 
    370                 375                 380


Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe 
385                 390                 395                 400


Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile 
                405                 410                 415


Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro 
            420                 425                 430


Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg 
        435                 440                 445


Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys 
    450                 455                 460


Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg 
465                 470                 475                 480


Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
                485                 490


<210>  10355
<211>  2150
<212>  DNA
<213>  Homo sapiens

<400>  10355
cgcggcggct ggcgtcggga aagtacagta aaaagtccga gtgcagccgc cgggcgcagg     60

atgggatccg gctcctccag ctaccggccc aaggccatct acctggacat cgatggacgc    120

attcagaagg taatcttcag caagtactgc aactccagcg acatcatgga cctgttctgc    180

atcgccaccg gcctgcctcg gaacacgacc atctccctgc tgaccaccga cgacgccatg    240

gtctccatcg accccaccat gcccgcgaat tcagaacgca ctccgtacaa agtgagacct    300

gtggccatca agcaactctc cgctggtgtc gaggacaaga gaaccacaag ccgtggccag    360

tctgctgaga gaccactgag ggacagacgg gttgtgggcc tggagcagcc ccggagggaa    420

ggagcatttg aaagtggaca ggtagagccc aggcccagag agccccaggg ctgctaccag    480

gaaggccagc gcatccctcc agagagagaa gaattaatcc agagcgtgct ggcgcaggtt    540

gcagagcagt tctcaagagc attcaaaatc aatgaactga aagctgaagt tgcaaatcac    600

ttggctgtcc tagagaaacg cgtggaattg gaaggactaa aagtggtgga gattgagaaa    660

tgcaagagtg acattaagaa gatgagggag gagctggcgg ccagaagcag caggaccaac    720

tgcccctgta agtacagttt tttggataac cacaagaagt tgactcctcg acgcgatgtt    780

cccacttacc ccaagtacct gctctctcca gagaccatcg aggccctgcg gaagccgacc    840

tttgacgtct ggctttggga gcccaatgag atgctgagct gcctggagca catgtaccac    900

gacctcgggc tggtcaggga cttcagcatc aaccctgtca ccctcaggag gtggctgttc    960

tgcgtccacg acaactacag aaacaacccc ttccacaact tccggcactg cttctgcgtg   1020

gcccagatga tgtacagcat ggtctggctc tgcagtctcc aggagaagtt ctcacaaacg   1080

gatatcctga tcctaatgac agcggccatc tgccacgatc tggaccatcc cggctacaac   1140

aacacgtacc agatcaatgc ccgcacagag ctggcggtcc gctacaatga catctcaccg   1200

ctggagaacc accactgcgc cgtggccttc cagatcctcg ccgagcctga gtgcaacatc   1260

ttctccaaca tcccacctga tgggttcaag cagatccgac agggaatgat cacattaatc   1320

ttggccactg acatggcaag acatgcagaa attatggatt ctttcaaaga gaaaatggag   1380

aattttgact acagcaacga ggagcacatg accctgctga agatgatttt gataaaatgc   1440

tgtgatatct ctaacgaggt ccgtccaatg gaagtcgcag agccttgggt ggactgttta   1500

ttagaggaat attttatgca gagcgaccgt gagaagtcag aaggccttcc tgtggcaccg   1560

ttcatggacc gagacaaagt gaccaaggcc acagcccaga ttgggttcat caagtttgtc   1620

ctgatcccaa tgtttgaaac agtgaccaag ctcttcccca tggttgagga gatcatgctg   1680

cagccacttt gggaatcccg agatcgctac gaggagctga agcggataga tgacgccatg   1740

aaagagttac agaagaagac tgacagcttg acgtctgggg ccaccgagaa gtccagagag   1800

agaagcagag atgtgaaaaa cagtgaagga gactgtgcct gaggaaagcg gggggcgtgg   1860

ctgcagttct ggacgggctg gccgagctgc gcgggatcct tgtgcaggga agagctgccc   1920

tgggcacctg gcaccacaag accatgtttt ctaagaacca ttttgttcac tgatacaaaa   1980

aaaaaaaaag gaattcatga tgctgtacag aattttattt ttaaactgtc ttttaaataa   2040

tatattctta tacggaaatg ggtactgtac ttcttctttg gtagagttgt gtatgctgct   2100

tccggtaagt tctctcatgg agacgaagga cactgtgctt ttcccccaga              2150


<210>  10356
<211>  593
<212>  PRT
<213>  Homo sapiens

<400>  10356

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Ala Gly Val Glu Asp Lys Arg Thr Thr 
                85                  90                  95


Ser Arg Gly Gln Ser Ala Glu Arg Pro Leu Arg Asp Arg Arg Val Val 
            100                 105                 110


Gly Leu Glu Gln Pro Arg Arg Glu Gly Ala Phe Glu Ser Gly Gln Val 
        115                 120                 125


Glu Pro Arg Pro Arg Glu Pro Gln Gly Cys Tyr Gln Glu Gly Gln Arg 
    130                 135                 140


Ile Pro Pro Glu Arg Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val 
145                 150                 155                 160


Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
                165                 170                 175


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
            180                 185                 190


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
        195                 200                 205


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
    210                 215                 220


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
225                 230                 235                 240


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
                245                 250                 255


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
            260                 265                 270


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
        275                 280                 285


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
    290                 295                 300


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
305                 310                 315                 320


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
                325                 330                 335


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
            340                 345                 350


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
        355                 360                 365


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
    370                 375                 380


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
385                 390                 395                 400


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
                405                 410                 415


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
            420                 425                 430


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
        435                 440                 445


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
    450                 455                 460


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
465                 470                 475                 480


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
                485                 490                 495


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
            500                 505                 510


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
        515                 520                 525


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
    530                 535                 540


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
545                 550                 555                 560


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
                565                 570                 575


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
            580                 585                 590


Ala 



<210>  10357
<211>  993
<212>  DNA
<213>  Homo sapiens

<400>  10357
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggtaat cttcagcaag    120

tactgcaact ccagcgacat catggacctg ttctgcatcg ccaccggcct gcctcggaac    180

acgaccatct ccctgctgac caccgacgac gccatggtct ccatcgaccc caccatgccc    240

gcgaattcag aacgcactcc gtacaaagtg agacctgtgg ccatcaagca actctccggt    300

aaggccctgc tgtcgttttt taaactaaaa gaaggaaaaa gaaatcttga gcttgcccct    360

gtgataaaat atatactagt taagcatttg aatctaagca tttgaaatat atatgagtta    420

cctttgaagc atttaactat atgttagtta agcatttgaa tctgcatttg aagccgatac    480

aactgcagaa tctgaaacct tgtactactg taagggctct gcctttctaa ccccagggag    540

aatagcatct gcctggggtt agcctccctt gtgtggattt tttcttactc cttttggcca    600

ctgcctgttc ctggtctatg gccgttccat tggctgcact gtctgtccct gcccctcggc    660

cagaggccat cccaaggact ttgcagttgc agggcggcat ccactctggt cttcctggcc    720

cagcacctgt cctccccgct ccactgtgag ttgccaaggc aggcatttgt ggcccctggg    780

atgccttggg gtgcctcata cagttacttg ggccgctgtg ttacaatcct ttttcttttt    840

cttttttttt ttttaaaaaa aaacggagtc tggtcctgtc acccagggct ggaatgcagt    900

ggcacgatct cggctcactg caacctctgc ctcccaagtt caagtgattc tcctgcctca    960

ccctcccagg tagctgggat tacaggcgtg cac                                 993


<210>  10358
<211>  122
<212>  PRT
<213>  Homo sapiens

<400>  10358

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Gly Lys Ala Leu Leu Ser Phe Phe Lys 
                85                  90                  95


Leu Lys Glu Gly Lys Arg Asn Leu Glu Leu Ala Pro Val Ile Lys Tyr 
            100                 105                 110


Ile Leu Val Lys His Leu Asn Leu Ser Ile 
        115                 120


<210>  10359
<211>  812
<212>  DNA
<213>  Homo sapiens

<400>  10359
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggtaat cttcagcaag    120

tactgcaact ccagcgacat catggacctg ttctgcatcg ccaccggcct gcctcggaac    180

acgaccatct ccctgctgac caccgacgac gccatggtct ccatcgaccc caccatgccc    240

gcgaattcag aacgcactcc gtacaaagtg agacctgtgg ccatcaagca actctccgat    300

attcatttct ccagcaccat ttgttgaaaa gatgatcttt tctcccactg aattaccatg    360

acacctttgt ggaaaatcga tgggccatgt atgtgtgagt ctttttctgg actccagatc    420

ctgtcgtgtg aatttacatg tcttaaaaca acagcacacc atcttgacta ccgtagataa    480

atagtaggtc ttgaaatcag gtactctaag ttatctctgg tttctttttt ctttttcaaa    540

aatgttattg cttttatttt caaataaatt ttagaatcag tctatgaatt gcttccaaaa    600

aaacagtctg ctaggatttt gactgaagtt gcattaaata tacagaccaa tgtgggaaga    660

attaatatct taagaatgtt gagtcttctg gttcataaat atggtctatc tccccattca    720

tttgggtttc ctttaatgtt tctcaataat gtgttaccat tgttaatatg aagtacttaa    780

taaatactga taaatacatc actatttcat gt                                  812


<210>  10360
<211>  96
<212>  PRT
<213>  Homo sapiens

<400>  10360

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Asn 
        35                  40                  45


Thr Thr Ile Ser Leu Leu Thr Thr Asp Asp Ala Met Val Ser Ile Asp 
    50                  55                  60


Pro Thr Met Pro Ala Asn Ser Glu Arg Thr Pro Tyr Lys Val Arg Pro 
65                  70                  75                  80


Val Ala Ile Lys Gln Leu Ser Asp Ile His Phe Ser Ser Thr Ile Cys 
                85                  90                  95


<210>  10361
<211>  1933
<212>  DNA
<213>  Homo sapiens

<400>  10361
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagctggt gtcgaggaca    120

agagaaccac aagccgtggc cagtctgctg agagaccact gagggacaga cgggttgtgg    180

gcctggagca gccccggagg gaaggagcat ttgaaagtgg acaggtagag cccaggccca    240

gagagcccca gggctgctac caggaaggcc agcgcatccc tccagagaga gaagaattaa    300

tccagagcgt gctggcgcag gttgcagagc agttctcaag agcattcaaa atcaatgaac    360

tgaaagctga agttgcaaat cacttggctg tcctagagaa acgcgtggaa ttggaaggac    420

taaaagtggt ggagattgag aaatgcaaga gtgacattaa gaagatgagg gaggagctgg    480

cggccagaag cagcaggacc aactgcccct gtaagtacag ttttttggat aaccacaaga    540

agttgactcc tcgacgcgat gttcccactt accccaagta cctgctctct ccagagacca    600

tcgaggccct gcggaagccg acctttgacg tctggctttg ggagcccaat gagatgctga    660

gctgcctgga gcacatgtac cacgacctcg ggctggtcag ggacttcagc atcaaccctg    720

tcaccctcag gaggtggctg ttctgcgtcc acgacaacta cagaaacaac cccttccaca    780

acttccggca ctgcttctgc gtggcccaga tgatgtacag catggtctgg ctctgcagtc    840

tccaggagaa gttctcacaa acggatatcc tgatcctaat gacagcggcc atctgccacg    900

atctggacca tcccggctac aacaacacgt accagatcaa tgcccgcaca gagctggcgg    960

tccgctacaa tgacatctca ccgctggaga accaccactg cgccgtggcc ttccagatcc   1020

tcgccgagcc tgagtgcaac atcttctcca acatcccacc tgatgggttc aagcagatcc   1080

gacagggaat gatcacatta atcttggcca ctgacatggc aagacatgca gaaattatgg   1140

attctttcaa agagaaaatg gagaattttg actacagcaa cgaggagcac atgaccctgc   1200

tgaagatgat tttgataaaa tgctgtgata tctctaacga ggtccgtcca atggaagtcg   1260

cagagccttg ggtggactgt ttattagagg aatattttat gcagagcgac cgtgagaagt   1320

cagaaggcct tcctgtggca ccgttcatgg accgagacaa agtgaccaag gccacagccc   1380

agattgggtt catcaagttt gtcctgatcc caatgtttga aacagtgacc aagctcttcc   1440

ccatggttga ggagatcatg ctgcagccac tttgggaatc ccgagatcgc tacgaggagc   1500

tgaagcggat agatgacgcc atgaaagagt tacagaagaa gactgacagc ttgacgtctg   1560

gggccaccga gaagtccaga gagagaagca gagatgtgaa aaacagtgaa ggagactgtg   1620

cctgaggaaa gcggggggcg tggctgcagt tctggacggg ctggccgagc tgcgcgggat   1680

ccttgtgcag ggaagagctg ccctgggcac ctggcaccac aagaccatgt tttctaagaa   1740

ccattttgtt cactgataca aaaaaaaaaa aaggaattca tgatgctgta cagaatttta   1800

tttttaaact gtcttttaaa taatatattc ttatacggaa atgggtactg tacttcttct   1860

ttggtagagt tgtgtatgct gcttccggta agttctctca tggagacgaa ggacactgtg   1920

cttttccccc aga                                                      1933


<210>  10362
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10362

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10363
<211>  1876
<212>  DNA
<213>  Homo sapiens

<400>  10363
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagcactc cgtacaaagt    120

gagacctgtg gccatcaagc aactctccgc aaaagaatgc agattttgca ttatctaaag    180

aggcggttcc gtgagcccac tgtgctgagt cacatatatt ccatcggtag agagaagaat    240

taatccagag cgtgctggcg caggttgcag agcagttctc aagagcattc aaaatcaatg    300

aactgaaagc tgaagttgca aatcacttgg ctgtcctaga gaaacgcgtg gaattggaag    360

gactaaaagt ggtggagatt gagaaatgca agagtgacat taagaagatg agggaggagc    420

tggcggccag aagcagcagg accaactgcc cctgtaagta cagttttttg gataaccaca    480

agaagttgac tcctcgacgc gatgttccca cttaccccaa gtacctgctc tctccagaga    540

ccatcgaggc cctgcggaag ccgacctttg acgtctggct ttgggagccc aatgagatgc    600

tgagctgcct ggagcacatg taccacgacc tcgggctggt cagggacttc agcatcaacc    660

ctgtcaccct caggaggtgg ctgttctgcg tccacgacaa ctacagaaac aaccccttcc    720

acaacttccg gcactgcttc tgcgtggccc agatgatgta cagcatggtc tggctctgca    780

gtctccagga gaagttctca caaacggata tcctgatcct aatgacagcg gccatctgcc    840

acgatctgga ccatcccggc tacaacaaca cgtaccagat caatgcccgc acagagctgg    900

cggtccgcta caatgacatc tcaccgctgg agaaccacca ctgcgccgtg gccttccaga    960

tcctcgccga gcctgagtgc aacatcttct ccaacatccc acctgatggg ttcaagcaga   1020

tccgacaggg aatgatcaca ttaatcttgg ccactgacat ggcaagacat gcagaaatta   1080

tggattcttt caaagagaaa atggagaatt ttgactacag caacgaggag cacatgaccc   1140

tgctgaagat gattttgata aaatgctgtg atatctctaa cgaggtccgt ccaatggaag   1200

tcgcagagcc ttgggtggac tgtttattag aggaatattt tatgcagagc gaccgtgaga   1260

agtcagaagg ccttcctgtg gcaccgttca tggaccgaga caaagtgacc aaggccacag   1320

cccagattgg gttcatcaag tttgtcctga tcccaatgtt tgaaacagtg accaagctct   1380

tccccatggt tgaggagatc atgctgcagc cactttggga atcccgagat cgctacgagg   1440

agctgaagcg gatagatgac gccatgaaag agttacagaa gaagactgac agcttgacgt   1500

ctggggccac cgagaagtcc agagagagaa gcagagatgt gaaaaacagt gaaggagact   1560

gtgcctgagg aaagcggggg gcgtggctgc agttctggac gggctggccg agctgcgcgg   1620

gatccttgtg cagggaagag ctgccctggg cacctggcac cacaagacca tgttttctaa   1680

gaaccatttt gttcactgat acaaaaaaaa aaaaaggaat tcatgatgct gtacagaatt   1740

ttatttttaa actgtctttt aaataatata ttcttatacg gaaatgggta ctgtacttct   1800

tctttggtag agttgtgtat gctgcttccg gtaagttctc tcatggagac gaaggacact   1860

gtgcttttcc cccaga                                                   1876


<210>  10364
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10364

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10365
<211>  1813
<212>  DNA
<213>  Homo sapiens

<400>  10365
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggtaat cttcagcaag    120

tactgcaact ccagcgacat catggacctg ttctgcatcg ccaccggcct gcctcgcact    180

ccgtacaaag tgagacctgt ggccatcaag caactctccg agcattcaaa atcaatgaac    240

tgaaagctga agttgcaaat cacttggctg tcctagagaa acgcgtggaa ttggaaggac    300

taaaagtggt ggagattgag aaatgcaaga gtgacattaa gaagatgagg gaggagctgg    360

cggccagaag cagcaggacc aactgcccct gtaagtacag ttttttggat aaccacaaga    420

agttgactcc tcgacgcgat gttcccactt accccaagta cctgctctct ccagagacca    480

tcgaggccct gcggaagccg acctttgacg tctggctttg ggagcccaat gagatgctga    540

gctgcctgga gcacatgtac cacgacctcg ggctggtcag ggacttcagc atcaaccctg    600

tcaccctcag gaggtggctg ttctgcgtcc acgacaacta cagaaacaac cccttccaca    660

acttccggca ctgcttctgc gtggcccaga tgatgtacag catggtctgg ctctgcagtc    720

tccaggagaa gttctcacaa acggatatcc tgatcctaat gacagcggcc atctgccacg    780

atctggacca tcccggctac aacaacacgt accagatcaa tgcccgcaca gagctggcgg    840

tccgctacaa tgacatctca ccgctggaga accaccactg cgccgtggcc ttccagatcc    900

tcgccgagcc tgagtgcaac atcttctcca acatcccacc tgatgggttc aagcagatcc    960

gacagggaat gatcacatta atcttggcca ctgacatggc aagacatgca gaaattatgg   1020

attctttcaa agagaaaatg gagaattttg actacagcaa cgaggagcac atgaccctgc   1080

tgaagatgat tttgataaaa tgctgtgata tctctaacga ggtccgtcca atggaagtcg   1140

cagagccttg ggtggactgt ttattagagg aatattttat gcagagcgac cgtgagaagt   1200

cagaaggcct tcctgtggca ccgttcatgg accgagacaa agtgaccaag gccacagccc   1260

agattgggtt catcaagttt gtcctgatcc caatgtttga aacagtgacc aagctcttcc   1320

ccatggttga ggagatcatg ctgcagccac tttgggaatc ccgagatcgc tacgaggagc   1380

tgaagcggat agatgacgcc atgaaagagt tacagaagaa gactgacagc ttgacgtctg   1440

gggccaccga gaagtccaga gagagaagca gagatgtgaa aaacagtgaa ggagactgtg   1500

cctgaggaaa gcggggggcg tggctgcagt tctggacggg ctggccgagc tgcgcgggat   1560

ccttgtgcag ggaagagctg ccctgggcac ctggcaccac aagaccatgt tttctaagaa   1620

ccattttgtt cactgataca aaaaaaaaaa aaggaattca tgatgctgta cagaatttta   1680

tttttaaact gtcttttaaa taatatattc ttatacggaa atgggtactg tacttcttct   1740

ttggtagagt tgtgtatgct gcttccggta agttctctca tggagacgaa ggacactgtg   1800

cttttccccc aga                                                      1813


<210>  10366
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10366

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10367
<211>  1875
<212>  DNA
<213>  Homo sapiens

<400>  10367
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggaaca cgaccatctc    120

cctgctgacc accgacgacg ccatggtctc catcgacccc accatgcccg cgaattcaga    180

acgcactccg tacaaagtga gacctgtggc catcaagcaa ctctccgaga gagaagaatt    240

aatccagagc gtgctggcgc aggttgcaga gcagttctca agagcattca aaatcaatga    300

actgaaagct gaagttgcaa atcacttggc tgtcctagag aaacgcgtgg aattggaagg    360

actaaaagtg gtggagattg agaaatgcaa gagtgacatt aagaagatga gggaggagct    420

ggcggccaga agcagcagga ccaactgccc ctgtaagtac agttttttgg ataaccacaa    480

gaagttgact cctcgacgcg atgttcccac ttaccccaag tacctgctct ctccagagac    540

catcgaggcc ctgcggaagc cgacctttga cgtctggctt tgggagccca atgagatgct    600

gagctgcctg gagcacatgt accacgacct cgggctggtc agggacttca gcatcaaccc    660

tgtcaccctc aggaggtggc tgttctgcgt ccacgacaac tacagaaaca accccttcca    720

caacttccgg cactgcttct gcgtggccca gatgatgtac agcatggtct ggctctgcag    780

tctccaggag aagttctcac aaacggatat cctgatccta atgacagcgg ccatctgcca    840

cgatctggac catcccggct acaacaacac gtaccagatc aatgcccgca cagagctggc    900

ggtccgctac aatgacatct caccgctgga gaaccaccac tgcgccgtgg ccttccagat    960

cctcgccgag cctgagtgca acatcttctc caacatccca cctgatgggt tcaagcagat   1020

ccgacaggga atgatcacat taatcttggc cactgacatg gcaagacatg cagaaattat   1080

ggattctttc aaagagaaaa tggagaattt tgactacagc aacgaggagc acatgaccct   1140

gctgaagatg attttgataa aatgctgtga tatctctaac gaggtccgtc caatggaagt   1200

cgcagagcct tgggtggact gtttattaga ggaatatttt atgcagagcg accgtgagaa   1260

gtcagaaggc cttcctgtgg caccgttcat ggaccgagac aaagtgacca aggccacagc   1320

ccagattggg ttcatcaagt ttgtcctgat cccaatgttt gaaacagtga ccaagctctt   1380

ccccatggtt gaggagatca tgctgcagcc actttgggaa tcccgagatc gctacgagga   1440

gctgaagcgg atagatgacg ccatgaaaga gttacagaag aagactgaca gcttgacgtc   1500

tggggccacc gagaagtcca gagagagaag cagagatgtg aaaaacagtg aaggagactg   1560

tgcctgagga aagcgggggg cgtggctgca gttctggacg ggctggccga gctgcgcggg   1620

atccttgtgc agggaagagc tgccctgggc acctggcacc acaagaccat gttttctaag   1680

aaccattttg ttcactgata caaaaaaaaa aaaaggaatt catgatgctg tacagaattt   1740

tatttttaaa ctgtctttta aataatatat tcttatacgg aaatgggtac tgtacttctt   1800

ctttggtaga gttgtgtatg ctgcttccgg taagttctct catggagacg aaggacactg   1860

tgcttttccc ccaga                                                    1875


<210>  10368
<211>  492
<212>  PRT
<213>  Homo sapiens

<400>  10368

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Thr Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Glu Arg 
        35                  40                  45


Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser 
    50                  55                  60


Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu 
65                  70                  75                  80


Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu 
                85                  90                  95


Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala 
            100                 105                 110


Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp 
        115                 120                 125


Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys 
    130                 135                 140


Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe 
145                 150                 155                 160


Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His 
                165                 170                 175


Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val 
            180                 185                 190


Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn 
        195                 200                 205


Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr 
    210                 215                 220


Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp 
225                 230                 235                 240


Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro 
                245                 250                 255


Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val 
            260                 265                 270


Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala 
        275                 280                 285


Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro 
    290                 295                 300


Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu 
305                 310                 315                 320


Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu 
                325                 330                 335


Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu 
            340                 345                 350


Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro 
        355                 360                 365


Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe 
    370                 375                 380


Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe 
385                 390                 395                 400


Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile 
                405                 410                 415


Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro 
            420                 425                 430


Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg 
        435                 440                 445


Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys 
    450                 455                 460


Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg 
465                 470                 475                 480


Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
                485                 490


<210>  10369
<211>  1698
<212>  DNA
<213>  Homo sapiens

<400>  10369
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagagcat tcaaaatcaa    120

tgaactgaaa gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaattgga    180

aggactaaaa gtggtggaga ttgagaaatg caagagtgac attaagaaga tgagggagga    240

gctggcggcc agaagcagca ggaccaactg cccctgtaag tacagttttt tggataacca    300

caagaagttg actcctcgac gcgatgttcc cacttacccc aagtacctgc tctctccaga    360

gaccatcgag gccctgcgga agccgacctt tgacgtctgg ctttgggagc ccaatgagat    420

gctgagctgc ctggagcaca tgtaccacga cctcgggctg gtcagggact tcagcatcaa    480

ccctgtcacc ctcaggaggt ggctgttctg cgtccacgac aactacagaa acaacccctt    540

ccacaacttc cggcactgct tctgcgtggc ccagatgatg tacagcatgg tctggctctg    600

cagtctccag gagaagttct cacaaacgga tatcctgatc ctaatgacag cggccatctg    660

ccacgatctg gaccatcccg gctacaacaa cacgtaccag atcaatgccc gcacagagct    720

ggcggtccgc tacaatgaca tctcaccgct ggagaaccac cactgcgccg tggccttcca    780

gatcctcgcc gagcctgagt gcaacatctt ctccaacatc ccacctgatg ggttcaagca    840

gatccgacag ggaatgatca cattaatctt ggccactgac atggcaagac atgcagaaat    900

tatggattct ttcaaagaga aaatggagaa ttttgactac agcaacgagg agcacatgac    960

cctgctgaag atgattttga taaaatgctg tgatatctct aacgaggtcc gtccaatgga   1020

agtcgcagag ccttgggtgg actgtttatt agaggaatat tttatgcaga gcgaccgtga   1080

gaagtcagaa ggccttcctg tggcaccgtt catggaccga gacaaagtga ccaaggccac   1140

agcccagatt gggttcatca agtttgtcct gatcccaatg tttgaaacag tgaccaagct   1200

cttccccatg gttgaggaga tcatgctgca gccactttgg gaatcccgag atcgctacga   1260

ggagctgaag cggatagatg acgccatgaa agagttacag aagaagactg acagcttgac   1320

gtctggggcc accgagaagt ccagagagag aagcagagat gtgaaaaaca gtgaaggaga   1380

ctgtgcctga ggaaagcggg gggcgtggct gcagttctgg acgggctggc cgagctgcgc   1440

gggatccttg tgcagggaag agctgccctg ggcacctggc accacaagac catgttttct   1500

aagaaccatt ttgttcactg atacaaaaaa aaaaaaagga attcatgatg ctgtacagaa   1560

ttttattttt aaactgtctt ttaaataata tattcttata cggaaatggg tactgtactt   1620

cttctttggt agagttgtgt atgctgcttc cggtaagttc tctcatggag acgaaggaca   1680

ctgtgctttt cccccaga                                                 1698


<210>  10370
<211>  433
<212>  PRT
<213>  Homo sapiens

<400>  10370

Met Asp Ala Phe Arg Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
1               5                   10                  15


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
            20                  25                  30


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
        35                  40                  45


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
    50                  55                  60


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
65                  70                  75                  80


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
                85                  90                  95


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
            100                 105                 110


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
        115                 120                 125


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
    130                 135                 140


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
145                 150                 155                 160


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
                165                 170                 175


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
            180                 185                 190


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
        195                 200                 205


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
    210                 215                 220


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
225                 230                 235                 240


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
                245                 250                 255


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
            260                 265                 270


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
        275                 280                 285


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
    290                 295                 300


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
305                 310                 315                 320


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
                325                 330                 335


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
            340                 345                 350


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
        355                 360                 365


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
    370                 375                 380


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
385                 390                 395                 400


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
                405                 410                 415


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
            420                 425                 430


Ala 



<210>  10371
<211>  1657
<212>  DNA
<213>  Homo sapiens

<400>  10371
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagcactc cgtacaaagt    120

gagacctgtg gccatcaagc aactctccga gcattcaaaa tcaatgaact gaaagctgaa    180

gttgcaaatc acttggctgt cctagagaaa cgcgtggaat gaccaactgc ccctgtaagt    240

acagtttttt ggataaccac aagaagttga ctcctcgacg cgatgttccc acttacccca    300

agtacctgct ctctccagag accatcgagg ccctgcggaa gccgaccttt gacgtctggc    360

tttgggagcc caatgagatg ctgagctgcc tggagcacat gtaccacgac ctcgggctgg    420

tcagggactt cagcatcaac cctgtcaccc tcaggaggtg gctgttctgc gtccacgaca    480

actacagaaa caaccccttc cacaacttcc ggcactgctt ctgcgtggcc cagatgatgt    540

acagcatggt ctggctctgc agtctccagg agaagttctc acaaacggat atcctgatcc    600

taatgacagc ggccatctgc cacgatctgg accatcccgg ctacaacaac acgtaccaga    660

tcaatgcccg cacagagctg gcggtccgct acaatgacat ctcaccgctg gagaaccacc    720

actgcgccgt ggccttccag atcctcgccg agcctgagtg caacatcttc tccaacatcc    780

cacctgatgg gttcaagcag atccgacagg gaatgatcac attaatcttg gccactgaca    840

tggcaagaca tgcagaaatt atggattctt tcaaagagaa aatggagaat tttgactaca    900

gcaacgagga gcacatgacc ctgctgaaga tgattttgat aaaatgctgt gatatctcta    960

acgaggtccg tccaatggaa gtcgcagagc cttgggtgga ctgtttatta gaggaatatt   1020

ttatgcagag cgaccgtgag aagtcagaag gccttcctgt ggcaccgttc atggaccgag   1080

acaaagtgac caaggccaca gcccagattg ggttcatcaa gtttgtcctg atcccaatgt   1140

ttgaaacagt gaccaagctc ttccccatgg ttgaggagat catgctgcag ccactttggg   1200

aatcccgaga tcgctacgag gagctgaagc ggatagatga cgccatgaaa gagttacaga   1260

agaagactga cagcttgacg tctggggcca ccgagaagtc cagagagaga agcagagatg   1320

tgaaaaacag tgaaggagac tgtgcctgag gaaagcgggg ggcgtggctg cagttctgga   1380

cgggctggcc gagctgcgcg ggatccttgt gcagggaaga gctgccctgg gcacctggca   1440

ccacaagacc atgttttcta agaaccattt tgttcactga tacaaaaaaa aaaaaaggaa   1500

ttcatgatgc tgtacagaat tttattttta aactgtcttt taaataatat attcttatac   1560

ggaaatgggt actgtacttc ttctttggta gagttgtgta tgctgcttcc ggtaagttct   1620

ctcatggaga cgaaggacac tgtgcttttc ccccaga                            1657


<210>  10372
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  10372

Met Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
1               5                   10                  15


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
            20                  25                  30


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
        35                  40                  45


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
    50                  55                  60


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
65                  70                  75                  80


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
                85                  90                  95


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
            100                 105                 110


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
        115                 120                 125


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
    130                 135                 140


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
145                 150                 155                 160


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
                165                 170                 175


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
            180                 185                 190


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
        195                 200                 205


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
    210                 215                 220


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
225                 230                 235                 240


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
                245                 250                 255


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
            260                 265                 270


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
        275                 280                 285


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
    290                 295                 300


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
305                 310                 315                 320


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
                325                 330                 335


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
            340                 345                 350


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
        355                 360                 365


Lys Asn Ser Glu Gly Asp Cys Ala 
    370                 375


<210>  10373
<211>  1776
<212>  DNA
<213>  Homo sapiens

<400>  10373
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggaaca cgaccatctc    120

cctgctgacc accgacgacg ccatggtctc catcgacccc accatgcccg cgaattcaga    180

acgagcattc aaaatcaatg aactgaaagc tgaagttgca aatcacttgg ctgtcctaga    240

gaaacgcgtg gaattggaag gactaaaagt ggtggagatt gagaaatgca agagtgacat    300

taagaagatg agggaggagc tggcggccag aagcagcagg accaactgcc cctgtaagta    360

cagttttttg gataaccaca agaagttgac tcctcgacgc gatgttccca cttaccccaa    420

gtacctgctc tctccagaga ccatcgaggc cctgcggaag ccgacctttg acgtctggct    480

ttgggagccc aatgagatgc tgagctgcct ggagcacatg taccacgacc tcgggctggt    540

cagggacttc agcatcaacc ctgtcaccct caggaggtgg ctgttctgcg tccacgacaa    600

ctacagaaac aaccccttcc acaacttccg gcactgcttc tgcgtggccc agatgatgta    660

cagcatggtc tggctctgca gtctccagga gaagttctca caaacggata tcctgatcct    720

aatgacagcg gccatctgcc acgatctgga ccatcccggc tacaacaaca cgtaccagat    780

caatgcccgc acagagctgg cggtccgcta caatgacatc tcaccgctgg agaaccacca    840

ctgcgccgtg gccttccaga tcctcgccga gcctgagtgc aacatcttct ccaacatccc    900

acctgatggg ttcaagcaga tccgacaggg aatgatcaca ttaatcttgg ccactgacat    960

ggcaagacat gcagaaatta tggattcttt caaagagaaa atggagaatt ttgactacag   1020

caacgaggag cacatgaccc tgctgaagat gattttgata aaatgctgtg atatctctaa   1080

cgaggtccgt ccaatggaag tcgcagagcc ttgggtggac tgtttattag aggaatattt   1140

tatgcagagc gaccgtgaga agtcagaagg ccttcctgtg gcaccgttca tggaccgaga   1200

caaagtgacc aaggccacag cccagattgg gttcatcaag tttgtcctga tcccaatgtt   1260

tgaaacagtg accaagctct tccccatggt tgaggagatc atgctgcagc cactttggga   1320

atcccgagat cgctacgagg agctgaagcg gatagatgac gccatgaaag agttacagaa   1380

gaagactgac agcttgacgt ctggggccac cgagaagtcc agagagagaa gcagagatgt   1440

gaaaaacagt gaaggagact gtgcctgagg aaagcggggg gcgtggctgc agttctggac   1500

gggctggccg agctgcgcgg gatccttgtg cagggaagag ctgccctggg cacctggcac   1560

cacaagacca tgttttctaa gaaccatttt gttcactgat acaaaaaaaa aaaaaggaat   1620

tcatgatgct gtacagaatt ttatttttaa actgtctttt aaataatata ttcttatacg   1680

gaaatgggta ctgtacttct tctttggtag agttgtgtat gctgcttccg gtaagttctc   1740

tcatggagac gaaggacact gtgcttttcc cccaga                             1776


<210>  10374
<211>  459
<212>  PRT
<213>  Homo sapiens

<400>  10374

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
        35                  40                  45


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
    50                  55                  60


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
65                  70                  75                  80


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
                85                  90                  95


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
            100                 105                 110


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
        115                 120                 125


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
    130                 135                 140


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
145                 150                 155                 160


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
                165                 170                 175


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
            180                 185                 190


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
        195                 200                 205


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
    210                 215                 220


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
225                 230                 235                 240


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
                245                 250                 255


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
            260                 265                 270


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
        275                 280                 285


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
    290                 295                 300


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
305                 310                 315                 320


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
                325                 330                 335


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
            340                 345                 350


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
        355                 360                 365


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
    370                 375                 380


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
385                 390                 395                 400


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
                405                 410                 415


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
            420                 425                 430


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
        435                 440                 445


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
    450                 455


<210>  10375
<211>  2055
<212>  DNA
<213>  Homo sapiens

<400>  10375
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggaaca cgaccatctc    120

cctgctgacc accgacgacg ccatggtctc catcgacccc accatgcccg cgaattcaga    180

acgcactccg tacaaagtga gacctgtggc catcaagcaa ctctccgctg gtgtcgagga    240

caagagaacc acaagccgtg gccagtctgc tgagagacca ctgagggaca gacgggttgt    300

gggcctggag cagccccgga gggaaggagc atttgaaagt ggacaggtag agcccaggcc    360

cagagagccc cagggctgct accaggaagg ccagcgcatc cctccagaga gagaagaatt    420

aatccagagc gtgctggcgc aggttgcaga gcagttctca agagcattca aaatcaatga    480

actgaaagct gaagttgcaa atcacttggc tgtcctagag aaacgcgtgg aattggaagg    540

actaaaagtg gtggagattg agaaatgcaa gagtgacatt aagaagatga gggaggagct    600

ggcggccaga agcagcagga ccaactgccc ctgtaagtac agttttttgg ataaccacaa    660

gaagttgact cctcgacgcg atgttcccac ttaccccaag tacctgctct ctccagagac    720

catcgaggcc ctgcggaagc cgacctttga cgtctggctt tgggagccca atgagatgct    780

gagctgcctg gagcacatgt accacgacct cgggctggtc agggacttca gcatcaaccc    840

tgtcaccctc aggaggtggc tgttctgcgt ccacgacaac tacagaaaca accccttcca    900

caacttccgg cactgcttct gcgtggccca gatgatgtac agcatggtct ggctctgcag    960

tctccaggag aagttctcac aaacggatat cctgatccta atgacagcgg ccatctgcca   1020

cgatctggac catcccggct acaacaacac gtaccagatc aatgcccgca cagagctggc   1080

ggtccgctac aatgacatct caccgctgga gaaccaccac tgcgccgtgg ccttccagat   1140

cctcgccgag cctgagtgca acatcttctc caacatccca cctgatgggt tcaagcagat   1200

ccgacaggga atgatcacat taatcttggc cactgacatg gcaagacatg cagaaattat   1260

ggattctttc aaagagaaaa tggagaattt tgactacagc aacgaggagc acatgaccct   1320

gctgaagatg attttgataa aatgctgtga tatctctaac gaggtccgtc caatggaagt   1380

cgcagagcct tgggtggact gtttattaga ggaatatttt atgcagagcg accgtgagaa   1440

gtcagaaggc cttcctgtgg caccgttcat ggaccgagac aaagtgacca aggccacagc   1500

ccagattggg ttcatcaagt ttgtcctgat cccaatgttt gaaacagtga ccaagctctt   1560

ccccatggtt gaggagatca tgctgcagcc actttgggaa tcccgagatc gctacgagga   1620

gctgaagcgg atagatgacg ccatgaaaga gttacagaag aagactgaca gcttgacgtc   1680

tggggccacc gagaagtcca gagagagaag cagagatgtg aaaaacagtg aaggagactg   1740

tgcctgagga aagcgggggg cgtggctgca gttctggacg ggctggccga gctgcgcggg   1800

atccttgtgc agggaagagc tgccctgggc acctggcacc acaagaccat gttttctaag   1860

aaccattttg ttcactgata caaaaaaaaa aaaaggaatt catgatgctg tacagaattt   1920

tatttttaaa ctgtctttta aataatatat tcttatacgg aaatgggtac tgtacttctt   1980

ctttggtaga gttgtgtatg ctgcttccgg taagttctct catggagacg aaggacactg   2040

tgcttttccc ccaga                                                    2055


<210>  10376
<211>  552
<212>  PRT
<213>  Homo sapiens

<400>  10376

Met Asp Ala Phe Arg Arg Asn Thr Thr Ile Ser Leu Leu Thr Thr Asp 
1               5                   10                  15


Asp Ala Met Val Ser Ile Asp Pro Thr Met Pro Ala Asn Ser Glu Arg 
            20                  25                  30


Thr Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Ala Gly 
        35                  40                  45


Val Glu Asp Lys Arg Thr Thr Ser Arg Gly Gln Ser Ala Glu Arg Pro 
    50                  55                  60


Leu Arg Asp Arg Arg Val Val Gly Leu Glu Gln Pro Arg Arg Glu Gly 
65                  70                  75                  80


Ala Phe Glu Ser Gly Gln Val Glu Pro Arg Pro Arg Glu Pro Gln Gly 
                85                  90                  95


Cys Tyr Gln Glu Gly Gln Arg Ile Pro Pro Glu Arg Glu Glu Leu Ile 
            100                 105                 110


Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys 
        115                 120                 125


Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu 
    130                 135                 140


Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys 
145                 150                 155                 160


Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser 
                165                 170                 175


Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
            180                 185                 190


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
        195                 200                 205


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
    210                 215                 220


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
225                 230                 235                 240


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
                245                 250                 255


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
            260                 265                 270


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
        275                 280                 285


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
    290                 295                 300


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
305                 310                 315                 320


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
                325                 330                 335


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
            340                 345                 350


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
        355                 360                 365


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
    370                 375                 380


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
385                 390                 395                 400


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
                405                 410                 415


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
            420                 425                 430


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
        435                 440                 445


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
    450                 455                 460


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
465                 470                 475                 480


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
                485                 490                 495


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
            500                 505                 510


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
        515                 520                 525


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
    530                 535                 540


Lys Asn Ser Glu Gly Asp Cys Ala 
545                 550


<210>  10377
<211>  1742
<212>  DNA
<213>  Homo sapiens

<400>  10377
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagcactc cgtacaaagt    120

gagacctgtg gccatcaagc aactctccga gcattcaaaa tcaatgaact gaaagctgaa    180

gttgcaaatc acttggctgt cctagagaaa cgcgtggaat tggaaggact aaaagtggtg    240

gagattgaga aatgcaagag tgacattaag aagatgaggg aggagctggc ggccagaagc    300

agcaggacca actgcccctg taagtacagt tttttggata accacaagaa gttgactcct    360

cgacgcgatg ttcccactta ccccaagtac ctgctctctc cagagaccat cgaggccctg    420

cggaagccga cctttgacgt ctggctttgg gagcccaatg agatgctgag ctgcctggag    480

cacatgtacc acgacctcgg gctggtcagg gacttcagca tcaaccctgt caccctcagg    540

aggtggctgt tctgcgtcca cgacaactac agaaacaacc ccttccacaa cttccggcac    600

tgcttctgcg tggcccagat gatgtacagc atggtctggc tctgcagtct ccaggagaag    660

ttctcacaaa cggatatcct gatcctaatg acagcggcca tctgccacga tctggaccat    720

cccggctaca acaacacgta ccagatcaat gcccgcacag agctggcggt ccgctacaat    780

gacatctcac cgctggagaa ccaccactgc gccgtggcct tccagatcct cgccgagcct    840

gagtgcaaca tcttctccaa catcccacct gatgggttca agcagatccg acagggaatg    900

atcacattaa tcttggccac tgacatggca agacatgcag aaattatgga ttctttcaaa    960

gagaaaatgg agaattttga ctacagcaac gaggagcaca tgaccctgct gaagatgatt   1020

ttgataaaat gctgtgatat ctctaacgag gtccgtccaa tggaagtcgc agagccttgg   1080

gtggactgtt tattagagga atattttatg cagagcgacc gtgagaagtc agaaggcctt   1140

cctgtggcac cgttcatgga ccgagacaaa gtgaccaagg ccacagccca gattgggttc   1200

atcaagtttg tcctgatccc aatgtttgaa acagtgacca agctcttccc catggttgag   1260

gagatcatgc tgcagccact ttgggaatcc cgagatcgct acgaggagct gaagcggata   1320

gatgacgcca tgaaagagtt acagaagaag actgacagct tgacgtctgg ggccaccgag   1380

aagtccagag agagaagcag agatgtgaaa aacagtgaag gagactgtgc ctgaggaaag   1440

cggggggcgt ggctgcagtt ctggacgggc tggccgagct gcgcgggatc cttgtgcagg   1500

gaagagctgc cctgggcacc tggcaccaca agaccatgtt ttctaagaac cattttgttc   1560

actgatacaa aaaaaaaaaa aggaattcat gatgctgtac agaattttat ttttaaactg   1620

tcttttaaat aatatattct tatacggaaa tgggtactgt acttcttctt tggtagagtt   1680

gtgtatgctg cttccggtaa gttctctcat ggagacgaag gacactgtgc ttttccccca   1740

ga                                                                  1742


<210>  10378
<211>  465
<212>  PRT
<213>  Homo sapiens

<400>  10378

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys His Ser Val Gln Ser Glu Thr Cys Gly 
            20                  25                  30


His Gln Ala Thr Leu Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu 
        35                  40                  45


Val Ala Asn His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly 
    50                  55                  60


Leu Lys Val Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met 
65                  70                  75                  80


Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys 
                85                  90                  95


Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val 
            100                 105                 110


Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu 
        115                 120                 125


Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu 
    130                 135                 140


Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe 
145                 150                 155                 160


Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp 
                165                 170                 175


Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val 
            180                 185                 190


Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys 
        195                 200                 205


Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His 
    210                 215                 220


Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg 
225                 230                 235                 240


Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His 
                245                 250                 255


His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile 
            260                 265                 270


Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met 
        275                 280                 285


Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met 
    290                 295                 300


Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu 
305                 310                 315                 320


His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser 
                325                 330                 335


Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu 
            340                 345                 350


Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu 
        355                 360                 365


Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala 
    370                 375                 380


Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val 
385                 390                 395                 400


Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp 
                405                 410                 415


Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met 
            420                 425                 430


Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu 
        435                 440                 445


Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys 
    450                 455                 460


Ala 
465


<210>  10379
<211>  2048
<212>  DNA
<213>  Homo sapiens

<400>  10379
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggtaat cttcagcaag    120

tactgcaact ccagcgacat catggacctg ttctgcatcg ccaccggcct gcctcgcact    180

ccgtacaaag tgagacctgt ggccatcaag caactctccg ctggtgtcga ggacaagaga    240

accacaagcc gtggccagtc tgctgagaga ccactgaggg acagacgggt tgtgggcctg    300

gagcagcccc ggagggaagg agcatttgaa agtggacagg tagagcccag gcccagagag    360

ccccagggct gctaccagga aggccagcgc atccctccag agagagaaga attaatccag    420

agcgtgctgg cgcaggttgc agagcagttc tcaagagcat tcaaaatcaa tgaactgaaa    480

gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaattgga aggactaaaa    540

gtggtggaga ttgagaaatg caagagtgac attaagaaga tgagggagga gctggcggcc    600

agaagcagca ggaccaactg cccctgtaag tacagttttt tggataacca caagaagttg    660

actcctcgac gcgatgttcc cacttacccc aagtacctgc tctctccaga gaccatcgag    720

gccctgcgga agccgacctt tgacgtctgg ctttgggagc ccaatgagat gctgagctgc    780

ctggagcaca tgtaccacga cctcgggctg gtcagggact tcagcatcaa ccctgtcacc    840

ctcaggaggt ggctgttctg cgtccacgac aactacagaa acaacccctt ccacaacttc    900

cggcactgct tctgcgtggc ccagatgatg tacagcatgg tctggctctg cagtctccag    960

gagaagttct cacaaacgga tatcctgatc ctaatgacag cggccatctg ccacgatctg   1020

gaccatcccg gctacaacaa cacgtaccag atcaatgccc gcacagagct ggcggtccgc   1080

tacaatgaca tctcaccgct ggagaaccac cactgcgccg tggccttcca gatcctcgcc   1140

gagcctgagt gcaacatctt ctccaacatc ccacctgatg ggttcaagca gatccgacag   1200

ggaatgatca cattaatctt ggccactgac atggcaagac atgcagaaat tatggattct   1260

ttcaaagaga aaatggagaa ttttgactac agcaacgagg agcacatgac cctgctgaag   1320

atgattttga taaaatgctg tgatatctct aacgaggtcc gtccaatgga agtcgcagag   1380

ccttgggtgg actgtttatt agaggaatat tttatgcaga gcgaccgtga gaagtcagaa   1440

ggccttcctg tggcaccgtt catggaccga gacaaagtga ccaaggccac agcccagatt   1500

gggttcatca agtttgtcct gatcccaatg tttgaaacag tgaccaagct cttccccatg   1560

gttgaggaga tcatgctgca gccactttgg gaatcccgag atcgctacga ggagctgaag   1620

cggatagatg acgccatgaa agagttacag aagaagactg acagcttgac gtctggggcc   1680

accgagaagt ccagagagag aagcagagat gtgaaaaaca gtgaaggaga ctgtgcctga   1740

ggaaagcggg gggcgtggct gcagttctgg acgggctggc cgagctgcgc gggatccttg   1800

tgcagggaag agctgccctg ggcacctggc accacaagac catgttttct aagaaccatt   1860

ttgttcactg atacaaaaaa aaaaaaagga attcatgatg ctgtacagaa ttttattttt   1920

aaactgtctt ttaaataata tattcttata cggaaatggg tactgtactt cttctttggt   1980

agagttgtgt atgctgcttc cggtaagttc tctcatggag acgaaggaca ctgtgctttt   2040

cccccaga                                                            2048


<210>  10380
<211>  567
<212>  PRT
<213>  Homo sapiens

<400>  10380

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Thr 
        35                  40                  45


Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Ala Gly Val 
    50                  55                  60


Glu Asp Lys Arg Thr Thr Ser Arg Gly Gln Ser Ala Glu Arg Pro Leu 
65                  70                  75                  80


Arg Asp Arg Arg Val Val Gly Leu Glu Gln Pro Arg Arg Glu Gly Ala 
                85                  90                  95


Phe Glu Ser Gly Gln Val Glu Pro Arg Pro Arg Glu Pro Gln Gly Cys 
            100                 105                 110


Tyr Gln Glu Gly Gln Arg Ile Pro Pro Glu Arg Glu Glu Leu Ile Gln 
        115                 120                 125


Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg Ala Phe Lys Ile 
    130                 135                 140


Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala Val Leu Glu Lys 
145                 150                 155                 160


Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile Glu Lys Cys Lys 
                165                 170                 175


Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg 
            180                 185                 190


Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu 
        195                 200                 205


Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro 
    210                 215                 220


Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp 
225                 230                 235                 240


Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp Leu 
                245                 250                 255


Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp 
            260                 265                 270


Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe 
        275                 280                 285


Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp Leu 
    290                 295                 300


Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met 
305                 310                 315                 320


Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr 
                325                 330                 335


Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile 
            340                 345                 350


Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu Ala 
        355                 360                 365


Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys 
    370                 375                 380


Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala 
385                 390                 395                 400


Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe 
                405                 410                 415


Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu Ile 
            420                 425                 430


Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu 
        435                 440                 445


Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg 
    450                 455                 460


Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys 
465                 470                 475                 480


Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile 
                485                 490                 495


Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile 
            500                 505                 510


Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys 
        515                 520                 525


Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu 
    530                 535                 540


Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys 
545                 550                 555                 560


Asn Ser Glu Gly Asp Cys Ala 
                565


<210>  10381
<211>  1753
<212>  DNA
<213>  Homo sapiens

<400>  10381
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagagaga gaagaattaa    120

tccagagcgt gctggcgcag gttgcagagc agttctcaag agcattcaaa atcaatgaac    180

tgaaagctga agttgcaaat cacttggctg tcctagagaa acgcgtggaa ttggaaggac    240

taaaagtggt ggagattgag aaatgcaaga gtgacattaa gaagatgagg gaggagctgg    300

cggccagaag cagcaggacc aactgcccct gtaagtacag ttttttggat aaccacaaga    360

agttgactcc tcgacgcgat gttcccactt accccaagta cctgctctct ccagagacca    420

tcgaggccct gcggaagccg acctttgacg tctggctttg ggagcccaat gagatgctga    480

gctgcctgga gcacatgtac cacgacctcg ggctggtcag ggacttcagc atcaaccctg    540

tcaccctcag gaggtggctg ttctgcgtcc acgacaacta cagaaacaac cccttccaca    600

acttccggca ctgcttctgc gtggcccaga tgatgtacag catggtctgg ctctgcagtc    660

tccaggagaa gttctcacaa acggatatcc tgatcctaat gacagcggcc atctgccacg    720

atctggacca tcccggctac aacaacacgt accagatcaa tgcccgcaca gagctggcgg    780

tccgctacaa tgacatctca ccgctggaga accaccactg cgccgtggcc ttccagatcc    840

tcgccgagcc tgagtgcaac atcttctcca acatcccacc tgatgggttc aagcagatcc    900

gacagggaat gatcacatta atcttggcca ctgacatggc aagacatgca gaaattatgg    960

attctttcaa agagaaaatg gagaattttg actacagcaa cgaggagcac atgaccctgc   1020

tgaagatgat tttgataaaa tgctgtgata tctctaacga ggtccgtcca atggaagtcg   1080

cagagccttg ggtggactgt ttattagagg aatattttat gcagagcgac cgtgagaagt   1140

cagaaggcct tcctgtggca ccgttcatgg accgagacaa agtgaccaag gccacagccc   1200

agattgggtt catcaagttt gtcctgatcc caatgtttga aacagtgacc aagctcttcc   1260

ccatggttga ggagatcatg ctgcagccac tttgggaatc ccgagatcgc tacgaggagc   1320

tgaagcggat agatgacgcc atgaaagagt tacagaagaa gactgacagc ttgacgtctg   1380

gggccaccga gaagtccaga gagagaagca gagatgtgaa aaacagtgaa ggagactgtg   1440

cctgaggaaa gcggggggcg tggctgcagt tctggacggg ctggccgagc tgcgcgggat   1500

ccttgtgcag ggaagagctg ccctgggcac ctggcaccac aagaccatgt tttctaagaa   1560

ccattttgtt cactgataca aaaaaaaaaa aaggaattca tgatgctgta cagaatttta   1620

tttttaaact gtcttttaaa taatatattc ttatacggaa atgggtactg tacttcttct   1680

ttggtagagt tgtgtatgct gcttccggta agttctctca tggagacgaa ggacactgtg   1740

cttttccccc aga                                                      1753


<210>  10382
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10382

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10383
<211>  2000
<212>  DNA
<213>  Homo sapiens

<400>  10383
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggaaca cgaccatctc    120

cctgctgacc accgacgacg ccatggtctc catcgacccc accatgcccg cgaattcaga    180

acgcactccg tacaaagtga gacctgtggc catcaagcaa ctctccgctg gtgtcgagga    240

caagagaacc acaagccgtg gccagtctgc tgagagacca ctgagggaca gacgggttgt    300

gggcctggag cagccccgga gggaaggagc atttgaaagt ggacaggtag agcccaggcc    360

cagagagccc cagggctgct accaggaagg ccagcgcatc cctccagagc attcaaaatc    420

aatgaactga aagctgaagt tgcaaatcac ttggctgtcc tagagaaacg cgtggaattg    480

gaaggactaa aagtggtgga gattgagaaa tgcaagagtg acattaagaa gatgagggag    540

gagctggcgg ccagaagcag caggaccaac tgcccctgta agtacagttt tttggataac    600

cacaagaagt tgactcctcg acgcgatgtt cccacttacc ccaagtacct gctctctcca    660

gagaccatcg aggccctgcg gaagccgacc tttgacgtct ggctttggga gcccaatgag    720

atgctgagct gcctggagca catgtaccac gacctcgggc tggtcaggga cttcagcatc    780

aaccctgtca ccctcaggag gtggctgttc tgcgtccacg acaactacag aaacaacccc    840

ttccacaact tccggcactg cttctgcgtg gcccagatga tgtacagcat ggtctggctc    900

tgcagtctcc aggagaagtt ctcacaaacg gatatcctga tcctaatgac agcggccatc    960

tgccacgatc tggaccatcc cggctacaac aacacgtacc agatcaatgc ccgcacagag   1020

ctggcggtcc gctacaatga catctcaccg ctggagaacc accactgcgc cgtggccttc   1080

cagatcctcg ccgagcctga gtgcaacatc ttctccaaca tcccacctga tgggttcaag   1140

cagatccgac agggaatgat cacattaatc ttggccactg acatggcaag acatgcagaa   1200

attatggatt ctttcaaaga gaaaatggag aattttgact acagcaacga ggagcacatg   1260

accctgctga agatgatttt gataaaatgc tgtgatatct ctaacgaggt ccgtccaatg   1320

gaagtcgcag agccttgggt ggactgttta ttagaggaat attttatgca gagcgaccgt   1380

gagaagtcag aaggccttcc tgtggcaccg ttcatggacc gagacaaagt gaccaaggcc   1440

acagcccaga ttgggttcat caagtttgtc ctgatcccaa tgtttgaaac agtgaccaag   1500

ctcttcccca tggttgagga gatcatgctg cagccacttt gggaatcccg agatcgctac   1560

gaggagctga agcggataga tgacgccatg aaagagttac agaagaagac tgacagcttg   1620

acgtctgggg ccaccgagaa gtccagagag agaagcagag atgtgaaaaa cagtgaagga   1680

gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct ggacgggctg gccgagctgc   1740

gcgggatcct tgtgcaggga agagctgccc tgggcacctg gcaccacaag accatgtttt   1800

ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag gaattcatga tgctgtacag   1860

aattttattt ttaaactgtc ttttaaataa tatattctta tacggaaatg ggtactgtac   1920

ttcttctttg gtagagttgt gtatgctgct tccggtaagt tctctcatgg agacgaagga   1980

cactgtgctt ttcccccaga                                               2000


<210>  10384
<211>  386
<212>  PRT
<213>  Homo sapiens

<400>  10384

Met Arg Glu Glu Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys 
1               5                   10                  15


Lys Tyr Ser Phe Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp 
            20                  25                  30


Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala 
        35                  40                  45


Leu Arg Lys Pro Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met 
    50                  55                  60


Leu Ser Cys Leu Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp 
65                  70                  75                  80


Phe Ser Ile Asn Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His 
                85                  90                  95


Asp Asn Tyr Arg Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys 
            100                 105                 110


Val Ala Gln Met Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu 
        115                 120                 125


Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys 
    130                 135                 140


His Asp Leu Asp His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala 
145                 150                 155                 160


Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn 
                165                 170                 175


His His Cys Ala Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn 
            180                 185                 190


Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly 
        195                 200                 205


Met Ile Thr Leu Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile 
    210                 215                 220


Met Asp Ser Phe Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu 
225                 230                 235                 240


Glu His Met Thr Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile 
                245                 250                 255


Ser Asn Glu Val Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys 
            260                 265                 270


Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly 
        275                 280                 285


Leu Pro Val Ala Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr 
    290                 295                 300


Ala Gln Ile Gly Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr 
305                 310                 315                 320


Val Thr Lys Leu Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu 
                325                 330                 335


Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala 
            340                 345                 350


Met Lys Glu Leu Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr 
        355                 360                 365


Glu Lys Ser Arg Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp 
    370                 375                 380


Cys Ala 
385


<210>  10385
<211>  1977
<212>  DNA
<213>  Homo sapiens

<400>  10385
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagcactc cgtacaaagt    120

gagacctgtg gccatcaagc aactctccgc tggtgtcgag gacaagagaa ccacaagccg    180

tggccagtct gctgagagac cactgaggga cagacgggtt gtgggcctgg agcagccccg    240

gagggaagga gcatttgaaa gtggacaggt agagcccagg cccagagagc cccagggctg    300

ctaccaggaa ggccagcgca tccctccaga gagagaagaa ttaatccaga gcgtgctggc    360

gcaggttgca gagcagttct caagagcatt caaaatcaat gaactgaaag ctgaagttgc    420

aaatcacttg gctgtcctag agaaacgcgt ggaattggaa ggactaaaag tggtggagat    480

tgagaaatgc aagagtgaca ttaagaagat gagggaggag ctggcggcca gaagcagcag    540

gaccaactgc ccctgtaagt acagtttttt ggataaccac aagaagttga ctcctcgacg    600

cgatgttccc acttacccca agtacctgct ctctccagag accatcgagg ccctgcggaa    660

gccgaccttt gacgtctggc tttgggagcc caatgagatg ctgagctgcc tggagcacat    720

gtaccacgac ctcgggctgg tcagggactt cagcatcaac cctgtcaccc tcaggaggtg    780

gctgttctgc gtccacgaca actacagaaa caaccccttc cacaacttcc ggcactgctt    840

ctgcgtggcc cagatgatgt acagcatggt ctggctctgc agtctccagg agaagttctc    900

acaaacggat atcctgatcc taatgacagc ggccatctgc cacgatctgg accatcccgg    960

ctacaacaac acgtaccaga tcaatgcccg cacagagctg gcggtccgct acaatgacat   1020

ctcaccgctg gagaaccacc actgcgccgt ggccttccag atcctcgccg agcctgagtg   1080

caacatcttc tccaacatcc cacctgatgg gttcaagcag atccgacagg gaatgatcac   1140

attaatcttg gccactgaca tggcaagaca tgcagaaatt atggattctt tcaaagagaa   1200

aatggagaat tttgactaca gcaacgagga gcacatgacc ctgctgaaga tgattttgat   1260

aaaatgctgt gatatctcta acgaggtccg tccaatggaa gtcgcagagc cttgggtgga   1320

ctgtttatta gaggaatatt ttatgcagag cgaccgtgag aagtcagaag gccttcctgt   1380

ggcaccgttc atggaccgag acaaagtgac caaggccaca gcccagattg ggttcatcaa   1440

gtttgtcctg atcccaatgt ttgaaacagt gaccaagctc ttccccatgg ttgaggagat   1500

catgctgcag ccactttggg aatcccgaga tcgctacgag gagctgaagc ggatagatga   1560

cgccatgaaa gagttacaga agaagactga cagcttgacg tctggggcca ccgagaagtc   1620

cagagagaga agcagagatg tgaaaaacag tgaaggagac tgtgcctgag gaaagcgggg   1680

ggcgtggctg cagttctgga cgggctggcc gagctgcgcg ggatccttgt gcagggaaga   1740

gctgccctgg gcacctggca ccacaagacc atgttttcta agaaccattt tgttcactga   1800

tacaaaaaaa aaaaaaggaa ttcatgatgc tgtacagaat tttattttta aactgtcttt   1860

taaataatat attcttatac ggaaatgggt actgtacttc ttctttggta gagttgtgta   1920

tgctgcttcc ggtaagttct ctcatggaga cgaaggacac tgtgcttttc ccccaga      1977


<210>  10386
<211>  526
<212>  PRT
<213>  Homo sapiens

<400>  10386

Met Asp Ala Phe Arg Ser Thr Pro Tyr Lys Val Arg Pro Val Ala Ile 
1               5                   10                  15


Lys Gln Leu Ser Ala Gly Val Glu Asp Lys Arg Thr Thr Ser Arg Gly 
            20                  25                  30


Gln Ser Ala Glu Arg Pro Leu Arg Asp Arg Arg Val Val Gly Leu Glu 
        35                  40                  45


Gln Pro Arg Arg Glu Gly Ala Phe Glu Ser Gly Gln Val Glu Pro Arg 
    50                  55                  60


Pro Arg Glu Pro Gln Gly Cys Tyr Gln Glu Gly Gln Arg Ile Pro Pro 
65                  70                  75                  80


Glu Arg Glu Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln 
                85                  90                  95


Phe Ser Arg Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn 
            100                 105                 110


His Leu Ala Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val 
        115                 120                 125


Val Glu Ile Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu 
    130                 135                 140


Leu Ala Ala Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe 
145                 150                 155                 160


Leu Asp Asn His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr 
                165                 170                 175


Pro Lys Tyr Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro 
            180                 185                 190


Thr Phe Asp Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu 
        195                 200                 205


Glu His Met Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn 
    210                 215                 220


Pro Val Thr Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg 
225                 230                 235                 240


Asn Asn Pro Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met 
                245                 250                 255


Met Tyr Ser Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln 
            260                 265                 270


Thr Asp Ile Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp 
        275                 280                 285


His Pro Gly Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu 
    290                 295                 300


Ala Val Arg Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala 
305                 310                 315                 320


Val Ala Phe Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn 
                325                 330                 335


Ile Pro Pro Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu 
            340                 345                 350


Ile Leu Ala Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe 
        355                 360                 365


Lys Glu Lys Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr 
    370                 375                 380


Leu Leu Lys Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val 
385                 390                 395                 400


Arg Pro Met Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu 
                405                 410                 415


Tyr Phe Met Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala 
            420                 425                 430


Pro Phe Met Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly 
        435                 440                 445


Phe Ile Lys Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu 
    450                 455                 460


Phe Pro Met Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg 
465                 470                 475                 480


Asp Arg Tyr Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu 
                485                 490                 495


Gln Lys Lys Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg 
            500                 505                 510


Glu Arg Ser Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
        515                 520                 525


<210>  10387
<211>  1868
<212>  DNA
<213>  Homo sapiens

<400>  10387
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggtaat cttcagcaag    120

tactgcaact ccagcgacat catggacctg ttctgcatcg ccaccggcct gcctcgcact    180

ccgtacaaag tgagacctgt ggccatcaag caactctccg agagagaaga attaatccag    240

agcgtgctgg cgcaggttgc agagcagttc tcaagagcat tcaaaatcaa tgaactgaaa    300

gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaattgga aggactaaaa    360

gtggtggaga ttgagaaatg caagagtgac attaagaaga tgagggagga gctggcggcc    420

agaagcagca ggaccaactg cccctgtaag tacagttttt tggataacca caagaagttg    480

actcctcgac gcgatgttcc cacttacccc aagtacctgc tctctccaga gaccatcgag    540

gccctgcgga agccgacctt tgacgtctgg ctttgggagc ccaatgagat gctgagctgc    600

ctggagcaca tgtaccacga cctcgggctg gtcagggact tcagcatcaa ccctgtcacc    660

ctcaggaggt ggctgttctg cgtccacgac aactacagaa acaacccctt ccacaacttc    720

cggcactgct tctgcgtggc ccagatgatg tacagcatgg tctggctctg cagtctccag    780

gagaagttct cacaaacgga tatcctgatc ctaatgacag cggccatctg ccacgatctg    840

gaccatcccg gctacaacaa cacgtaccag atcaatgccc gcacagagct ggcggtccgc    900

tacaatgaca tctcaccgct ggagaaccac cactgcgccg tggccttcca gatcctcgcc    960

gagcctgagt gcaacatctt ctccaacatc ccacctgatg ggttcaagca gatccgacag   1020

ggaatgatca cattaatctt ggccactgac atggcaagac atgcagaaat tatggattct   1080

ttcaaagaga aaatggagaa ttttgactac agcaacgagg agcacatgac cctgctgaag   1140

atgattttga taaaatgctg tgatatctct aacgaggtcc gtccaatgga agtcgcagag   1200

ccttgggtgg actgtttatt agaggaatat tttatgcaga gcgaccgtga gaagtcagaa   1260

ggccttcctg tggcaccgtt catggaccga gacaaagtga ccaaggccac agcccagatt   1320

gggttcatca agtttgtcct gatcccaatg tttgaaacag tgaccaagct cttccccatg   1380

gttgaggaga tcatgctgca gccactttgg gaatcccgag atcgctacga ggagctgaag   1440

cggatagatg acgccatgaa agagttacag aagaagactg acagcttgac gtctggggcc   1500

accgagaagt ccagagagag aagcagagat gtgaaaaaca gtgaaggaga ctgtgcctga   1560

ggaaagcggg gggcgtggct gcagttctgg acgggctggc cgagctgcgc gggatccttg   1620

tgcagggaag agctgccctg ggcacctggc accacaagac catgttttct aagaaccatt   1680

ttgttcactg atacaaaaaa aaaaaaagga attcatgatg ctgtacagaa ttttattttt   1740

aaactgtctt ttaaataata tattcttata cggaaatggg tactgtactt cttctttggt   1800

agagttgtgt atgctgcttc cggtaagttc tctcatggag acgaaggaca ctgtgctttt   1860

cccccaga                                                            1868


<210>  10388
<211>  507
<212>  PRT
<213>  Homo sapiens

<400>  10388

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Val Ile Phe Ser Lys Tyr Cys Asn Ser 
            20                  25                  30


Ser Asp Ile Met Asp Leu Phe Cys Ile Ala Thr Gly Leu Pro Arg Thr 
        35                  40                  45


Pro Tyr Lys Val Arg Pro Val Ala Ile Lys Gln Leu Ser Glu Arg Glu 
    50                  55                  60


Glu Leu Ile Gln Ser Val Leu Ala Gln Val Ala Glu Gln Phe Ser Arg 
65                  70                  75                  80


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
                85                  90                  95


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
            100                 105                 110


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
        115                 120                 125


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
    130                 135                 140


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
145                 150                 155                 160


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
                165                 170                 175


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
            180                 185                 190


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
        195                 200                 205


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
    210                 215                 220


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
225                 230                 235                 240


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
                245                 250                 255


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
            260                 265                 270


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
        275                 280                 285


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
    290                 295                 300


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
305                 310                 315                 320


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
                325                 330                 335


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
            340                 345                 350


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
        355                 360                 365


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
    370                 375                 380


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
385                 390                 395                 400


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
                405                 410                 415


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
            420                 425                 430


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
        435                 440                 445


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
    450                 455                 460


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
465                 470                 475                 480


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
                485                 490                 495


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
            500                 505


<210>  10389
<211>  1613
<212>  DNA
<213>  Homo sapiens

<400>  10389
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaagagcat tcaaaatcaa    120

tgaactgaaa gctgaagttg caaatcactt ggctgtccta gagaaacgcg tggaatgacc    180

aactgcccct gtaagtacag ttttttggat aaccacaaga agttgactcc tcgacgcgat    240

gttcccactt accccaagta cctgctctct ccagagacca tcgaggccct gcggaagccg    300

acctttgacg tctggctttg ggagcccaat gagatgctga gctgcctgga gcacatgtac    360

cacgacctcg ggctggtcag ggacttcagc atcaaccctg tcaccctcag gaggtggctg    420

ttctgcgtcc acgacaacta cagaaacaac cccttccaca acttccggca ctgcttctgc    480

gtggcccaga tgatgtacag catggtctgg ctctgcagtc tccaggagaa gttctcacaa    540

acggatatcc tgatcctaat gacagcggcc atctgccacg atctggacca tcccggctac    600

aacaacacgt accagatcaa tgcccgcaca gagctggcgg tccgctacaa tgacatctca    660

ccgctggaga accaccactg cgccgtggcc ttccagatcc tcgccgagcc tgagtgcaac    720

atcttctcca acatcccacc tgatgggttc aagcagatcc gacagggaat gatcacatta    780

atcttggcca ctgacatggc aagacatgca gaaattatgg attctttcaa agagaaaatg    840

gagaattttg actacagcaa cgaggagcac atgaccctgc tgaagatgat tttgataaaa    900

tgctgtgata tctctaacga ggtccgtcca atggaagtcg cagagccttg ggtggactgt    960

ttattagagg aatattttat gcagagcgac cgtgagaagt cagaaggcct tcctgtggca   1020

ccgttcatgg accgagacaa agtgaccaag gccacagccc agattgggtt catcaagttt   1080

gtcctgatcc caatgtttga aacagtgacc aagctcttcc ccatggttga ggagatcatg   1140

ctgcagccac tttgggaatc ccgagatcgc tacgaggagc tgaagcggat agatgacgcc   1200

atgaaagagt tacagaagaa gactgacagc ttgacgtctg gggccaccga gaagtccaga   1260

gagagaagca gagatgtgaa aaacagtgaa ggagactgtg cctgaggaaa gcggggggcg   1320

tggctgcagt tctggacggg ctggccgagc tgcgcgggat ccttgtgcag ggaagagctg   1380

ccctgggcac ctggcaccac aagaccatgt tttctaagaa ccattttgtt cactgataca   1440

aaaaaaaaaa aaggaattca tgatgctgta cagaatttta tttttaaact gtcttttaaa   1500

taatatattc ttatacggaa atgggtactg tacttcttct ttggtagagt tgtgtatgct   1560

gcttccggta agttctctca tggagacgaa ggacactgtg cttttccccc aga          1613


<210>  10390
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  10390

Met Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn His Lys Lys 
1               5                   10                  15


Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr Leu Leu Ser 
            20                  25                  30


Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp Val Trp Leu 
        35                  40                  45


Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met Tyr His Asp 
    50                  55                  60


Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr Leu Arg Arg 
65                  70                  75                  80


Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro Phe His Asn 
                85                  90                  95


Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser Met Val Trp 
            100                 105                 110


Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile Leu Ile Leu 
        115                 120                 125


Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly Tyr Asn Asn 
    130                 135                 140


Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg Tyr Asn Asp 
145                 150                 155                 160


Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe Gln Ile Leu 
                165                 170                 175


Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro Asp Gly Phe 
            180                 185                 190


Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala Thr Asp Met 
        195                 200                 205


Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys Met Glu Asn 
    210                 215                 220


Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys Met Ile Leu 
225                 230                 235                 240


Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met Glu Val Ala 
                245                 250                 255


Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met Gln Ser Asp 
            260                 265                 270


Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met Asp Arg Asp 
        275                 280                 285


Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys Phe Val Leu 
    290                 295                 300


Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met Val Glu Glu 
305                 310                 315                 320


Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr Glu Glu Leu 
                325                 330                 335


Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys Thr Asp Ser 
            340                 345                 350


Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser Arg Asp Val 
        355                 360                 365


Lys Asn Ser Glu Gly Asp Cys Ala 
    370                 375


<210>  10391
<211>  1820
<212>  DNA
<213>  Homo sapiens

<400>  10391
acagtaaaaa gtccgagtgc agccgccggg cgcaggatgg gatccggctc ctccagctac     60

cggcccaagg ccatctacct ggacatcgat ggacgcattc agaaggaaca cgaccatctc    120

cctgctgacc accgacgacg ccatggtctc catcgacccc accatgcccg cgaattcaga    180

acgcactccg tacaaagtga gacctgtggc catcaagcaa ctctccgagc attcaaaatc    240

aatgaactga aagctgaagt tgcaaatcac ttggctgtcc tagagaaacg cgtggaattg    300

gaaggactaa aagtggtgga gattgagaaa tgcaagagtg acattaagaa gatgagggag    360

gagctggcgg ccagaagcag caggaccaac tgcccctgta agtacagttt tttggataac    420

cacaagaagt tgactcctcg acgcgatgtt cccacttacc ccaagtacct gctctctcca    480

gagaccatcg aggccctgcg gaagccgacc tttgacgtct ggctttggga gcccaatgag    540

atgctgagct gcctggagca catgtaccac gacctcgggc tggtcaggga cttcagcatc    600

aaccctgtca ccctcaggag gtggctgttc tgcgtccacg acaactacag aaacaacccc    660

ttccacaact tccggcactg cttctgcgtg gcccagatga tgtacagcat ggtctggctc    720

tgcagtctcc aggagaagtt ctcacaaacg gatatcctga tcctaatgac agcggccatc    780

tgccacgatc tggaccatcc cggctacaac aacacgtacc agatcaatgc ccgcacagag    840

ctggcggtcc gctacaatga catctcaccg ctggagaacc accactgcgc cgtggccttc    900

cagatcctcg ccgagcctga gtgcaacatc ttctccaaca tcccacctga tgggttcaag    960

cagatccgac agggaatgat cacattaatc ttggccactg acatggcaag acatgcagaa   1020

attatggatt ctttcaaaga gaaaatggag aattttgact acagcaacga ggagcacatg   1080

accctgctga agatgatttt gataaaatgc tgtgatatct ctaacgaggt ccgtccaatg   1140

gaagtcgcag agccttgggt ggactgttta ttagaggaat attttatgca gagcgaccgt   1200

gagaagtcag aaggccttcc tgtggcaccg ttcatggacc gagacaaagt gaccaaggcc   1260

acagcccaga ttgggttcat caagtttgtc ctgatcccaa tgtttgaaac agtgaccaag   1320

ctcttcccca tggttgagga gatcatgctg cagccacttt gggaatcccg agatcgctac   1380

gaggagctga agcggataga tgacgccatg aaagagttac agaagaagac tgacagcttg   1440

acgtctgggg ccaccgagaa gtccagagag agaagcagag atgtgaaaaa cagtgaagga   1500

gactgtgcct gaggaaagcg gggggcgtgg ctgcagttct ggacgggctg gccgagctgc   1560

gcgggatcct tgtgcaggga agagctgccc tgggcacctg gcaccacaag accatgtttt   1620

ctaagaacca ttttgttcac tgatacaaaa aaaaaaaaag gaattcatga tgctgtacag   1680

aattttattt ttaaactgtc ttttaaataa tatattctta tacggaaatg ggtactgtac   1740

ttcttctttg gtagagttgt gtatgctgct tccggtaagt tctctcatgg agacgaagga   1800

cactgtgctt ttcccccaga                                               1820


<210>  10392
<211>  491
<212>  PRT
<213>  Homo sapiens

<400>  10392

Met Gly Ser Gly Ser Ser Ser Tyr Arg Pro Lys Ala Ile Tyr Leu Asp 
1               5                   10                  15


Ile Asp Gly Arg Ile Gln Lys Glu His Asp His Leu Pro Ala Asp His 
            20                  25                  30


Arg Arg Arg His Gly Leu His Arg Pro His His Ala Arg Glu Phe Arg 
        35                  40                  45


Thr His Ser Val Gln Ser Glu Thr Cys Gly His Gln Ala Thr Leu Arg 
    50                  55                  60


Ala Phe Lys Ile Asn Glu Leu Lys Ala Glu Val Ala Asn His Leu Ala 
65                  70                  75                  80


Val Leu Glu Lys Arg Val Glu Leu Glu Gly Leu Lys Val Val Glu Ile 
                85                  90                  95


Glu Lys Cys Lys Ser Asp Ile Lys Lys Met Arg Glu Glu Leu Ala Ala 
            100                 105                 110


Arg Ser Ser Arg Thr Asn Cys Pro Cys Lys Tyr Ser Phe Leu Asp Asn 
        115                 120                 125


His Lys Lys Leu Thr Pro Arg Arg Asp Val Pro Thr Tyr Pro Lys Tyr 
    130                 135                 140


Leu Leu Ser Pro Glu Thr Ile Glu Ala Leu Arg Lys Pro Thr Phe Asp 
145                 150                 155                 160


Val Trp Leu Trp Glu Pro Asn Glu Met Leu Ser Cys Leu Glu His Met 
                165                 170                 175


Tyr His Asp Leu Gly Leu Val Arg Asp Phe Ser Ile Asn Pro Val Thr 
            180                 185                 190


Leu Arg Arg Trp Leu Phe Cys Val His Asp Asn Tyr Arg Asn Asn Pro 
        195                 200                 205


Phe His Asn Phe Arg His Cys Phe Cys Val Ala Gln Met Met Tyr Ser 
    210                 215                 220


Met Val Trp Leu Cys Ser Leu Gln Glu Lys Phe Ser Gln Thr Asp Ile 
225                 230                 235                 240


Leu Ile Leu Met Thr Ala Ala Ile Cys His Asp Leu Asp His Pro Gly 
                245                 250                 255


Tyr Asn Asn Thr Tyr Gln Ile Asn Ala Arg Thr Glu Leu Ala Val Arg 
            260                 265                 270


Tyr Asn Asp Ile Ser Pro Leu Glu Asn His His Cys Ala Val Ala Phe 
        275                 280                 285


Gln Ile Leu Ala Glu Pro Glu Cys Asn Ile Phe Ser Asn Ile Pro Pro 
    290                 295                 300


Asp Gly Phe Lys Gln Ile Arg Gln Gly Met Ile Thr Leu Ile Leu Ala 
305                 310                 315                 320


Thr Asp Met Ala Arg His Ala Glu Ile Met Asp Ser Phe Lys Glu Lys 
                325                 330                 335


Met Glu Asn Phe Asp Tyr Ser Asn Glu Glu His Met Thr Leu Leu Lys 
            340                 345                 350


Met Ile Leu Ile Lys Cys Cys Asp Ile Ser Asn Glu Val Arg Pro Met 
        355                 360                 365


Glu Val Ala Glu Pro Trp Val Asp Cys Leu Leu Glu Glu Tyr Phe Met 
    370                 375                 380


Gln Ser Asp Arg Glu Lys Ser Glu Gly Leu Pro Val Ala Pro Phe Met 
385                 390                 395                 400


Asp Arg Asp Lys Val Thr Lys Ala Thr Ala Gln Ile Gly Phe Ile Lys 
                405                 410                 415


Phe Val Leu Ile Pro Met Phe Glu Thr Val Thr Lys Leu Phe Pro Met 
            420                 425                 430


Val Glu Glu Ile Met Leu Gln Pro Leu Trp Glu Ser Arg Asp Arg Tyr 
        435                 440                 445


Glu Glu Leu Lys Arg Ile Asp Asp Ala Met Lys Glu Leu Gln Lys Lys 
    450                 455                 460


Thr Asp Ser Leu Thr Ser Gly Ala Thr Glu Lys Ser Arg Glu Arg Ser 
465                 470                 475                 480


Arg Asp Val Lys Asn Ser Glu Gly Asp Cys Ala 
                485                 490


<210>  10393
<211>  2365
<212>  DNA
<213>  Homo sapiens

<400>  10393
tagacaccag tcctgtagga ttagggccct acccttacga ctctctttaa attaatgact     60

tccttaaagg ctcaatctcc aaatatagtt actggggttt agggtctcag tatatgaatt    120

tggagggcac acaactcagt ctatagcact gatgcctcca tcaaaaatac cccatgtgac    180

agctggttga ggaggattaa cctcgaacca ccttattctc aatgccattt aggctgtagc    240

acactttctt ccaatcttat gctttttgtt tccaagtaga aaagaaacgc tttactgaag    300

aggccaccaa atacttccgg gagagagtca gcccagtgca tctgcaaatc ctgctgacta    360

acaatgaagc ctggaagaga ttcgtgactg cggctgaatt gcccagggat gaggcagatg    420

ctctctacga agctctgaag aagcttagaa catatgcagc tattgaggac gaatatgtgc    480

agcagaaaga tgagcagttt agggaatggt ttttgaaaga gtttccccaa gtcaagagga    540

agatccagga gtccatagaa aagcttcgtg cccttgcaaa tggtattgaa gaggtccaca    600

gaggctgcac catctccaat gtggtgtcca gctccactgg cgctgcctct ggcatcatgt    660

cccttgctgg tcttgttttg gcaccattta cagcagggac gagtctggcc cttactgcag    720

ctggggtagg gctgggagca gcgtctgctg tgactgggat caccaccagc atcgtggagc    780

actcatacac atcatcagca gaagctgaag ccagcaggct gactgcaacc agcattgacc    840

gattgaaggt atttaaggaa gttatgcgtg acatcacacc caacttactt tcccttctta    900

ataattatta cgaagccaca caaaccattg ggagtgaaat ccgtgccatc aggcaagcca    960

gagccagggc ccgactccct gtgaccacct ggcgaatctc agctggaagt ggtggtcaag   1020

cagagagaac gattgcaggc accacccggg cagtgagcag aggagcccgg atcctgagtg   1080

cgaccacttc aggcatcttc cttgcactgg atgtggtcaa ccttgtatac gagtcaaagc   1140

acttgcatga gggggcaaag tctgcatctg ctgaggagct gaggcggcag gctcaggagc   1200

tggaggagaa tctaatggag ctcactcaga tctatcagcg tctgaatcca tgccataccc   1260

actgacccca gaccagtgca gccagcaggg gaggtgagcc atacacaggc cacgacaaaa   1320

tgcaggcatt ttattagggg gataaagagg gcaaggtaaa gtttatggag ctgagtgtta   1380

gtgactttgg catttctgta gctgagcaca gcaggggagg ggttaatgca gatggcaagt   1440

gcaccaagga gaaggcagga atgctggagc ctggaataag ggaggagagg ggactggaga   1500

gtgtggggaa taggaagaag aaatttcctt tagactaacg aatatattgg ggggaggaat   1560

agaggggagg tgtgcaggaa ccagcaatga gaaggccagg aaaagaaaga gctgaaaatg   1620

cagaaagccg aagagttaga acttttggat acagcagaag aaacagcggc tccactaccg   1680

acctgccccc ggttcgatgt ccttccaaga atgaagtctt tccctggtga tggtcccctg   1740

ccctgtcttt ccagcatcca ctctgtcttg tcctcctgga agtgtatctc agtcagccag   1800

tggcttcttg atgatggcgg tggaggtggt ggttgtagtg tgatggatcc cctttaggtt   1860

atttaggggt atatgtcccc tgcttgaacc ctgaaggcca ggtaatgagc catggccatt   1920

gtccccagct gaggaccagg tgtctctaaa aacccaaaca tcctggagag tatgcgagaa   1980

cctaccaaga aaaacagtct cattactcat atacagcagg caaagagaca gaaaattaac   2040

tgaaaagcag tttagagact gggggaggcc ggatctctag agccatcctg ctgagtgccc   2100

tgtgtgtaag tcctaataaa ctcacctact caccaagctg gacttattcg agtcattcct   2160

tggtctcctg gctcctttct cgctttggga gcaagttcct gtctgaagtt tttgtctgaa   2220

cagtggtaaa ggtgatggtg atgatgtcag cagacagcag gaggacttga caaatgtcag   2280

ccctgcttgg ggccaggata cactgaggga acgatgacat tccaatgaaa ctccaaattc   2340

tgtattggaa aagtcattga tttgt                                         2365


<210>  10394
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10394

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10395
<211>  2320
<212>  DNA
<213>  Homo sapiens

<400>  10395
gatttcagcc aggctgtgcc acggagggca gaggccaccc aggtcagtca taggggatgc     60

agctgggaac accgcagggt ccctgccgga tgctcagagt ttaacgggga gacagaggcc    120

caaagagcca cacagagggt taagaaaaaa aacgaaccct tccagtcagg tcagtgactg    180

gagagctcca tggaaagtct ctcagtgacc tggctgctgg caccatggac tcagaaaaga    240

aacgctttac tgaagaggcc accaaatact tccgggagag agtcagccca gtgcatctgc    300

aaatcctgct gactaacaat gaagcctgga agagattcgt gactgcggct gaattgccca    360

gggatgaggc agatgctctc tacgaagctc tgaagaagct tagaacatat gcagctattg    420

aggacgaata tgtgcagcag aaagatgagc agtttaggga atggtttttg aaagagtttc    480

cccaagtcaa gaggaagatc caggagtcca tagaaaagct tcgtgccctt gcaaatggta    540

ttgaagaggt ccacagaggc tgcaccatct ccaatgtggt gtccagctcc actggcgctg    600

cctctggcat catgtccctt gctggtcttg ttttggcacc atttacagca gggacgagtc    660

tggcccttac tgcagctggg gtagggctgg gagcagcgtc tgctgtgact gggatcacca    720

ccagcatcgt ggagcactca tacacatcat cagcagaagc tgaagccagc aggctgactg    780

caaccagcat tgaccgattg aaggtattta aggaagttat gcgtgacatc acacccaact    840

tactttccct tcttaataat tattacgaag ccacacaaac cattgggagt gaaatccgtg    900

ccatcaggca agccagagcc agggcccgac tccctgtgac cacctggcga atctcagctg    960

gaagtggtgg tcaagcagag agaacgattg caggcaccac ccgggcagtg agcagaggag   1020

cccggatcct gagtgcgacc acttcaggca tcttccttgc actggatgtg gtcaaccttg   1080

tatacgagtc aaagcacttg catgaggggg caaagtctgc atctgctgag gagctgaggc   1140

ggcaggctca ggagctggag gagaatctaa tggagctcac tcagatctat cagcgtctga   1200

atccatgcca tacccactga ccccagacca gtgcagccag caggggaggt gagccataca   1260

caggccacga caaaatgcag gcattttatt agggggataa agagggcaag gtaaagttta   1320

tggagctgag tgttagtgac tttggcattt ctgtagctga gcacagcagg ggaggggtta   1380

atgcagatgg caagtgcacc aaggagaagg caggaatgct ggagcctgga ataagggagg   1440

agaggggact ggagagtgtg gggaatagga agaagaaatt tcctttagac taacgaatat   1500

attgggggga ggaatagagg ggaggtgtgc aggaaccagc aatgagaagg ccaggaaaag   1560

aaagagctga aaatgcagaa agccgaagag ttagaacttt tggatacagc agaagaaaca   1620

gcggctccac taccgacctg cccccggttc gatgtccttc caagaatgaa gtctttccct   1680

ggtgatggtc ccctgccctg tctttccagc atccactctg tcttgtcctc ctggaagtgt   1740

atctcagtca gccagtggct tcttgatgat ggcggtggag gtggtggttg tagtgtgatg   1800

gatccccttt aggttattta ggggtatatg tcccctgctt gaaccctgaa ggccaggtaa   1860

tgagccatgg ccattgtccc cagctgagga ccaggtgtct ctaaaaaccc aaacatcctg   1920

gagagtatgc gagaacctac caagaaaaac agtctcatta ctcatataca gcaggcaaag   1980

agacagaaaa ttaactgaaa agcagtttag agactggggg aggccggatc tctagagcca   2040

tcctgctgag tgccctgtgt gtaagtccta ataaactcac ctactcacca agctggactt   2100

attcgagtca ttccttggtc tcctggctcc tttctcgctt tgggagcaag ttcctgtctg   2160

aagtttttgt ctgaacagtg gtaaaggtga tggtgatgat gtcagcagac agcaggagga   2220

cttgacaaat gtcagccctg cttggggcca ggatacactg agggaacgat gacattccaa   2280

tgaaactcca aattctgtat tggaaaagtc attgatttgt                         2320


<210>  10396
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10396

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10397
<211>  2179
<212>  DNA
<213>  Homo sapiens

<400>  10397
gttgtccaga ggctggttgc ttttagtcca agtgctgcct cccacacctc ggatttcagc     60

caggctgtgc cacggagggc agaggccacc cagaaaagaa acgctttact gaagaggcca    120

ccaaatactt ccgggagaga gtcagcccag tgcatctgca aatcctgctg actaacaatg    180

aagcctggaa gagattcgtg actgcggctg aattgcccag ggatgaggca gatgctctct    240

acgaagctct gaagaagctt agaacatatg cagctattga ggacgaatat gtgcagcaga    300

aagatgagca gtttagggaa tggtttttga aagagtttcc ccaagtcaag aggaagatcc    360

aggagtccat agaaaagctt cgtgcccttg caaatggtat tgaagaggtc cacagaggct    420

gcaccatctc caatgtggtg tccagctcca ctggcgctgc ctctggcatc atgtcccttg    480

ctggtcttgt tttggcacca tttacagcag ggacgagtct ggcccttact gcagctgggg    540

tagggctggg agcagcgtct gctgtgactg ggatcaccac cagcatcgtg gagcactcat    600

acacatcatc agcagaagct gaagccagca ggctgactgc aaccagcatt gaccgattga    660

aggtatttaa ggaagttatg cgtgacatca cacccaactt actttccctt cttaataatt    720

attacgaagc cacacaaacc attgggagtg aaatccgtgc catcaggcaa gccagagcca    780

gggcccgact ccctgtgacc acctggcgaa tctcagctgg aagtggtggt caagcagaga    840

gaacgattgc aggcaccacc cgggcagtga gcagaggagc ccggatcctg agtgcgacca    900

cttcaggcat cttccttgca ctggatgtgg tcaaccttgt atacgagtca aagcacttgc    960

atgagggggc aaagtctgca tctgctgagg agctgaggcg gcaggctcag gagctggagg   1020

agaatctaat ggagctcact cagatctatc agcgtctgaa tccatgccat acccactgac   1080

cccagaccag tgcagccagc aggggaggtg agccatacac aggccacgac aaaatgcagg   1140

cattttatta gggggataaa gagggcaagg taaagtttat ggagctgagt gttagtgact   1200

ttggcatttc tgtagctgag cacagcaggg gaggggttaa tgcagatggc aagtgcacca   1260

aggagaaggc aggaatgctg gagcctggaa taagggagga gaggggactg gagagtgtgg   1320

ggaataggaa gaagaaattt cctttagact aacgaatata ttggggggag gaatagaggg   1380

gaggtgtgca ggaaccagca atgagaaggc caggaaaaga aagagctgaa aatgcagaaa   1440

gccgaagagt tagaactttt ggatacagca gaagaaacag cggctccact accgacctgc   1500

ccccggttcg atgtccttcc aagaatgaag tctttccctg gtgatggtcc cctgccctgt   1560

ctttccagca tccactctgt cttgtcctcc tggaagtgta tctcagtcag ccagtggctt   1620

cttgatgatg gcggtggagg tggtggttgt agtgtgatgg atccccttta ggttatttag   1680

gggtatatgt cccctgcttg aaccctgaag gccaggtaat gagccatggc cattgtcccc   1740

agctgaggac caggtgtctc taaaaaccca aacatcctgg agagtatgcg agaacctacc   1800

aagaaaaaca gtctcattac tcatatacag caggcaaaga gacagaaaat taactgaaaa   1860

gcagtttaga gactggggga ggccggatct ctagagccat cctgctgagt gccctgtgtg   1920

taagtcctaa taaactcacc tactcaccaa gctggactta ttcgagtcat tccttggtct   1980

cctggctcct ttctcgcttt gggagcaagt tcctgtctga agtttttgtc tgaacagtgg   2040

taaaggtgat ggtgatgatg tcagcagaca gcaggaggac ttgacaaatg tcagccctgc   2100

ttggggccag gatacactga gggaacgatg acattccaat gaaactccaa attctgtatt   2160

ggaaaagtca ttgatttgt                                                2179


<210>  10398
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10398

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10399
<211>  2332
<212>  DNA
<213>  Homo sapiens

<400>  10399
gaagctgggc catgttgtcc agaggctggt tgcttttagt ccaagtgctg cctcccacac     60

ctcggatttc agccaggctg tgccacggag ggcagaggcc acccaggtgg ctcacattca    120

gtcccacaat ttgctttctc ctcctcaagg gttaagaaaa aaaacgaacc cttccagtca    180

ggtcagtgac tggagagctc catggaaagt ctctcagtga cctggctgct ggcaccatgg    240

actcagaaaa gaaacgcttt actgaagagg ccaccaaata cttccgggag agagtcagcc    300

cagtgcatct gcaaatcctg ctgactaaca atgaagcctg gaagagattc gtgactgcgg    360

ctgaattgcc cagggatgag gcagatgctc tctacgaagc tctgaagaag cttagaacat    420

atgcagctat tgaggacgaa tatgtgcagc agaaagatga gcagtttagg gaatggtttt    480

tgaaagagtt tccccaagtc aagaggaaga tccaggagtc catagaaaag cttcgtgccc    540

ttgcaaatgg tattgaagag gtccacagag gctgcaccat ctccaatgtg gtgtccagct    600

ccactggcgc tgcctctggc atcatgtccc ttgctggtct tgttttggca ccatttacag    660

cagggacgag tctggccctt actgcagctg gggtagggct gggagcagcg tctgctgtga    720

ctgggatcac caccagcatc gtggagcact catacacatc atcagcagaa gctgaagcca    780

gcaggctgac tgcaaccagc attgaccgat tgaaggtatt taaggaagtt atgcgtgaca    840

tcacacccaa cttactttcc cttcttaata attattacga agccacacaa accattggga    900

gtgaaatccg tgccatcagg caagccagag ccagggcccg actccctgtg accacctggc    960

gaatctcagc tggaagtggt ggtcaagcag agagaacgat tgcaggcacc acccgggcag   1020

tgagcagagg agcccggatc ctgagtgcga ccacttcagg catcttcctt gcactggatg   1080

tggtcaacct tgtatacgag tcaaagcact tgcatgaggg ggcaaagtct gcatctgctg   1140

aggagctgag gcggcaggct caggagctgg aggagaatct aatggagctc actcagatct   1200

atcagcgtct gaatccatgc catacccact gaccccagac cagtgcagcc agcaggggag   1260

gtgagccata cacaggccac gacaaaatgc aggcatttta ttagggggat aaagagggca   1320

aggtaaagtt tatggagctg agtgttagtg actttggcat ttctgtagct gagcacagca   1380

ggggaggggt taatgcagat ggcaagtgca ccaaggagaa ggcaggaatg ctggagcctg   1440

gaataaggga ggagagggga ctggagagtg tggggaatag gaagaagaaa tttcctttag   1500

actaacgaat atattggggg gaggaataga ggggaggtgt gcaggaacca gcaatgagaa   1560

ggccaggaaa agaaagagct gaaaatgcag aaagccgaag agttagaact tttggataca   1620

gcagaagaaa cagcggctcc actaccgacc tgcccccggt tcgatgtcct tccaagaatg   1680

aagtctttcc ctggtgatgg tcccctgccc tgtctttcca gcatccactc tgtcttgtcc   1740

tcctggaagt gtatctcagt cagccagtgg cttcttgatg atggcggtgg aggtggtggt   1800

tgtagtgtga tggatcccct ttaggttatt taggggtata tgtcccctgc ttgaaccctg   1860

aaggccaggt aatgagccat ggccattgtc cccagctgag gaccaggtgt ctctaaaaac   1920

ccaaacatcc tggagagtat gcgagaacct accaagaaaa acagtctcat tactcatata   1980

cagcaggcaa agagacagaa aattaactga aaagcagttt agagactggg ggaggccgga   2040

tctctagagc catcctgctg agtgccctgt gtgtaagtcc taataaactc acctactcac   2100

caagctggac ttattcgagt cattccttgg tctcctggct cctttctcgc tttgggagca   2160

agttcctgtc tgaagttttt gtctgaacag tggtaaaggt gatggtgatg atgtcagcag   2220

acagcaggag gacttgacaa atgtcagccc tgcttggggc caggatacac tgagggaacg   2280

atgacattcc aatgaaactc caaattctgt attggaaaag tcattgattt gt           2332


<210>  10400
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10400

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10401
<211>  2295
<212>  DNA
<213>  Homo sapiens

<400>  10401
gaaactgaag ctgggccatg ttgtccagag gctggttgct tttagtccaa gtgctgcctc     60

ccacacctcg gatttcagcc aggctgtgcc acggagggca gaggccaccc agggttaaga    120

aaaaaaacga acccttccag tcaggtcagt gactggagag ctccatggaa agtctctcag    180

tgacctggct gctggcacca tggactcaga aaagaaacgc tttactgaag aggccaccaa    240

atacttccgg gagagagtca gcccagtgca tctgcaaatc ctgctgacta acaatgaagc    300

ctggaagaga ttcgtgactg cggctgaatt gcccagggat gaggcagatg ctctctacga    360

agctctgaag aagcttagaa catatgcagc tattgaggac gaatatgtgc agcagaaaga    420

tgagcagttt agggaatggt ttttgaaaga gtttccccaa gtcaagagga agatccagga    480

gtccatagaa aagcttcgtg cccttgcaaa tggtattgaa gaggtccaca gaggctgcac    540

catctccaat gtggtgtcca gctccactgg cgctgcctct ggcatcatgt cccttgctgg    600

tcttgttttg gcaccattta cagcagggac gagtctggcc cttactgcag ctggggtagg    660

gctgggagca gcgtctgctg tgactgggat caccaccagc atcgtggagc actcatacac    720

atcatcagca gaagctgaag ccagcaggct gactgcaacc agcattgacc gattgaaggt    780

atttaaggaa gttatgcgtg acatcacacc caacttactt tcccttctta ataattatta    840

cgaagccaca caaaccattg ggagtgaaat ccgtgccatc aggcaagcca gagccagggc    900

ccgactccct gtgaccacct ggcgaatctc agctggaagt ggtggtcaag cagagagaac    960

gattgcaggc accacccggg cagtgagcag aggagcccgg atcctgagtg cgaccacttc   1020

aggcatcttc cttgcactgg atgtggtcaa ccttgtatac gagtcaaagc acttgcatga   1080

gggggcaaag tctgcatctg ctgaggagct gaggcggcag gctcaggagc tggaggagaa   1140

tctaatggag ctcactcaga tctatcagcg tctgaatcca tgccataccc actgacccca   1200

gaccagtgca gccagcaggg gaggtgagcc atacacaggc cacgacaaaa tgcaggcatt   1260

ttattagggg gataaagagg gcaaggtaaa gtttatggag ctgagtgtta gtgactttgg   1320

catttctgta gctgagcaca gcaggggagg ggttaatgca gatggcaagt gcaccaagga   1380

gaaggcagga atgctggagc ctggaataag ggaggagagg ggactggaga gtgtggggaa   1440

taggaagaag aaatttcctt tagactaacg aatatattgg ggggaggaat agaggggagg   1500

tgtgcaggaa ccagcaatga gaaggccagg aaaagaaaga gctgaaaatg cagaaagccg   1560

aagagttaga acttttggat acagcagaag aaacagcggc tccactaccg acctgccccc   1620

ggttcgatgt ccttccaaga atgaagtctt tccctggtga tggtcccctg ccctgtcttt   1680

ccagcatcca ctctgtcttg tcctcctgga agtgtatctc agtcagccag tggcttcttg   1740

atgatggcgg tggaggtggt ggttgtagtg tgatggatcc cctttaggtt atttaggggt   1800

atatgtcccc tgcttgaacc ctgaaggcca ggtaatgagc catggccatt gtccccagct   1860

gaggaccagg tgtctctaaa aacccaaaca tcctggagag tatgcgagaa cctaccaaga   1920

aaaacagtct cattactcat atacagcagg caaagagaca gaaaattaac tgaaaagcag   1980

tttagagact gggggaggcc ggatctctag agccatcctg ctgagtgccc tgtgtgtaag   2040

tcctaataaa ctcacctact caccaagctg gacttattcg agtcattcct tggtctcctg   2100

gctcctttct cgctttggga gcaagttcct gtctgaagtt tttgtctgaa cagtggtaaa   2160

ggtgatggtg atgatgtcag cagacagcag gaggacttga caaatgtcag ccctgcttgg   2220

ggccaggata cactgaggga acgatgacat tccaatgaaa ctccaaattc tgtattggaa   2280

aagtcattga tttgt                                                    2295


<210>  10402
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10402

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10403
<211>  2192
<212>  DNA
<213>  Homo sapiens

<400>  10403
ttatgcagat gcacggctgg aggtgggatc cacacagctc agaacagctg gatcttgctc     60

acactctttc aagagaagct tccttgggtt aagaaaaaaa acgaaccctt ccagtcaggt    120

cagtgactgg agagctccat ggaaagtctc tcagtgacct ggctgctggc accatggact    180

cagaaaagaa acgctttact gaagagattc gtgactgcgg ctgaattgcc cagggatgag    240

gcagatgctc tctacgaagc tctgaagaag cttagaacat atgcagctat tgaggacgaa    300

tatgtgcagc agaaagatga gcagtttagg gaatggtttt tgaaagagtt tccccaagtc    360

aagaggaaga tccaggagtc catagaaaag cttcgtgccc ttgcaaatgg tattgaagag    420

gtccacagag gctgcaccat ctccaatgtg gtgtccagct ccactggcgc tgcctctggc    480

atcatgtccc ttgctggtct tgttttggca ccatttacag cagggacgag tctggccctt    540

actgcagctg gggtagggct gggagcagcg tctgctgtga ctgggatcac caccagcatc    600

gtggagcact catacacatc atcagcagaa gctgaagcca gcaggctgac tgcaaccagc    660

attgaccgat tgaaggtatt taaggaagtt atgcgtgaca tcacacccaa cttactttcc    720

cttcttaata attattacga agccacacaa accattggga gtgaaatccg tgccatcagg    780

caagccagag ccagggcccg actccctgtg accacctggc gaatctcagc tggaagtggt    840

ggtcaagcag agagaacgat tgcaggcacc acccgggcag tgagcagagg agcccggatc    900

ctgagtgcga ccacttcagg catcttcctt gcactggatg tggtcaacct tgtatacgag    960

tcaaagcact tgcatgaggg ggcaaagtct gcatctgctg aggagctgag gcggcaggct   1020

caggagctgg aggagaatct aatggagctc actcagatct atcagcgtct gaatccatgc   1080

catacccact gaccccagac cagtgcagcc agcaggggag gtgagccata cacaggccac   1140

gacaaaatgc aggcatttta ttagggggat aaagagggca aggtaaagtt tatggagctg   1200

agtgttagtg actttggcat ttctgtagct gagcacagca ggggaggggt taatgcagat   1260

ggcaagtgca ccaaggagaa ggcaggaatg ctggagcctg gaataaggga ggagagggga   1320

ctggagagtg tggggaatag gaagaagaaa tttcctttag actaacgaat atattggggg   1380

gaggaataga ggggaggtgt gcaggaacca gcaatgagaa ggccaggaaa agaaagagct   1440

gaaaatgcag aaagccgaag agttagaact tttggataca gcagaagaaa cagcggctcc   1500

actaccgacc tgcccccggt tcgatgtcct tccaagaatg aagtctttcc ctggtgatgg   1560

tcccctgccc tgtctttcca gcatccactc tgtcttgtcc tcctggaagt gtatctcagt   1620

cagccagtgg cttcttgatg atggcggtgg aggtggtggt tgtagtgtga tggatcccct   1680

ttaggttatt taggggtata tgtcccctgc ttgaaccctg aaggccaggt aatgagccat   1740

ggccattgtc cccagctgag gaccaggtgt ctctaaaaac ccaaacatcc tggagagtat   1800

gcgagaacct accaagaaaa acagtctcat tactcatata cagcaggcaa agagacagaa   1860

aattaactga aaagcagttt agagactggg ggaggccgga tctctagagc catcctgctg   1920

agtgccctgt gtgtaagtcc taataaactc acctactcac caagctggac ttattcgagt   1980

cattccttgg tctcctggct cctttctcgc tttgggagca agttcctgtc tgaagttttt   2040

gtctgaacag tggtaaaggt gatggtgatg atgtcagcag acagcaggag gacttgacaa   2100

atgtcagccc tgcttggggc caggatacac tgagggaacg atgacattcc aatgaaactc   2160

caaattctgt attggaaaag tcattgattt gt                                 2192


<210>  10404
<211>  317
<212>  PRT
<213>  Homo sapiens

<400>  10404

Met Glu Ser Leu Ser Val Thr Trp Leu Leu Ala Pro Trp Thr Gln Lys 
1               5                   10                  15


Arg Asn Ala Leu Leu Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg 
            20                  25                  30


Asp Glu Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr 
        35                  40                  45


Ala Ala Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg 
    50                  55                  60


Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu 
65                  70                  75                  80


Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His 
                85                  90                  95


Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala 
            100                 105                 110


Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala 
        115                 120                 125


Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala 
    130                 135                 140


Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr 
145                 150                 155                 160


Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp 
                165                 170                 175


Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu 
            180                 185                 190


Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser 
        195                 200                 205


Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val 
    210                 215                 220


Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr 
225                 230                 235                 240


Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser 
                245                 250                 255


Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val 
            260                 265                 270


Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu 
        275                 280                 285


Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu 
    290                 295                 300


Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
305                 310                 315


<210>  10405
<211>  2313
<212>  DNA
<213>  Homo sapiens

<400>  10405
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggtg gctcacattc agtcccacaa tttgctttct    120

cctcctcaag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    180

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    240

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    300

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    360

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    420

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    480

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    540

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    600

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct    660

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    720

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    780

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    840

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag    900

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg    960

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1020

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1080

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1140

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1200

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1260

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1320

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1380

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1440

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1500

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1560

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1620

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1680

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1740

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1800

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1860

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   1920

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   1980

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2040

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaagctgga cttattcgag   2100

tcattccttg gtctcctggc tcctttctcg ctttgggagc aagttcctgt ctgaagtttt   2160

tgtctgaaca gtggtaaagg tgatggtgat gatgtcagca gacagcagga ggacttgaca   2220

aatgtcagcc ctgcttgggg ccaggataca ctgagggaac gatgacattc caatgaaact   2280

ccaaattctg tattggaaaa gtcattgatt tgt                                2313


<210>  10406
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10406

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10407
<211>  2086
<212>  DNA
<213>  Homo sapiens

<400>  10407
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttgaaa agaaacgctt tactgaagag gccaccaaat    120

acttcaggga tgaggcagat gctctctacg aagctctgaa gaagcttaga acatatgcag    180

ctattgagga cgaatatgtg cagcagaaag atgagcagtt tagggaatgg tttttgaaag    240

agtttcccca agtcaagagg aagatccagg agtccataga aaagcttcgt gcccttgcaa    300

atggtattga agaggtccac agaggctgca ccatctccaa tgtggtgtcc agctccactg    360

gcgctgcctc tggcatcatg tcccttgctg gtcttgtttt ggcaccattt acagcaggga    420

cgagtctggc ccttactgca gctggggtag ggctgggagc agcgtctgct gtgactggga    480

tcaccaccag catcgtggag cactcataca catcatcagc agaagctgaa gccagcaggc    540

tgactgcaac cagcattgac cgattgaagg tatttaagga agttatgcgt gacatcacac    600

ccaacttact ttcccttctt aataattatt acgaagccac acaaaccatt gggagtgaaa    660

tccgtgccat caggcaagcc agagccaggg cccgactccc tgtgaccacc tggcgaatct    720

cagctggaag tggtggtcaa gcagagagaa cgattgcagg caccacccgg gcagtgagca    780

gaggagcccg gatcctgagt gcgaccactt caggcatctt ccttgcactg gatgtggtca    840

accttgtata cgagtcaaag cacttgcatg agggggcaaa gtctgcatct gctgaggagc    900

tgaggcggca ggctcaggag ctggaggaga atctaatgga gctcactcag atctatcagc    960

gtctgaatcc atgccatacc cactgacccc agaccagtgc agccagcagg ggaggtgagc   1020

catacacagg ccacgacaaa atgcaggcat tttattaggg ggataaagag ggcaaggtaa   1080

agtttatgga gctgagtgtt agtgactttg gcatttctgt agctgagcac agcaggggag   1140

gggttaatgc agatggcaag tgcaccaagg agaaggcagg aatgctggag cctggaataa   1200

gggaggagag gggactggag agtgtgggga ataggaagaa gaaatttcct ttagactaac   1260

gaatatattg gggggaggaa tagaggggag gtgtgcagga accagcaatg agaaggccag   1320

gaaaagaaag agctgaaaat gcagaaagcc gaagagttag aacttttgga tacagcagaa   1380

gaaacagcgg ctccactacc gacctgcccc cggttcgatg tccttccaag aatgaagtct   1440

ttccctggtg atggtcccct gccctgtctt tccagcatcc actctgtctt gtcctcctgg   1500

aagtgtatct cagtcagcca gtggcttctt gatgatggcg gtggaggtgg tggttgtagt   1560

gtgatggatc ccctttaggt tatttagggg tatatgtccc ctgcttgaac cctgaaggcc   1620

aggtaatgag ccatggccat tgtccccagc tgaggaccag gtgtctctaa aaacccaaac   1680

atcctggaga gtatgcgaga acctaccaag aaaaacagtc tcattactca tatacagcag   1740

gcaaagagac agaaaattaa ctgaaaagca gtttagagac tgggggaggc cggatctcta   1800

gagccatcct gctgagtgcc ctgtgtgtaa gtcctaataa actcacctac tcaccaagct   1860

ggacttattc gagtcattcc ttggtctcct ggctcctttc tcgctttggg agcaagttcc   1920

tgtctgaagt ttttgtctga acagtggtaa aggtgatggt gatgatgtca gcagacagca   1980

ggaggacttg acaaatgtca gccctgcttg gggccaggat acactgaggg aacgatgaca   2040

ttccaatgaa actccaaatt ctgtattgga aaagtcattg atttgt                  2086


<210>  10408
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  10408

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Lys Arg Asn Ala 
            20                  25                  30


Leu Leu Lys Arg Pro Pro Asn Thr Ser Gly Met Arg Gln Met Leu Ser 
        35                  40                  45


Thr Lys Leu 
    50


<210>  10409
<211>  2293
<212>  DNA
<213>  Homo sapiens

<400>  10409
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggac aaaaggaccc tgccttggtg tgagagtgag    120

ggcagaggga gctggagcaa gtagaatttc tctaaatacc agctggctgg ggcccaggag    180

attaaaaaac accgggctag gttggtcttg gcatttgctg acacgcaaag ggattgcaga    240

gatccagccc ctccaacctc cctctgtcca caggtggctc acattcagtc ccacaatttg    300

ctttctcctc ctcaagggtt aagaaaaaaa acgaaccctt ccagtcaggt cagtgactgg    360

agagctccat ggaaagtctc tcagtgacct ggctgctggc accatggact cagaaagatg    420

agcagtttag ggaatggttt ttgaaagagt ttccccaagt caagaggaag atccaggagt    480

ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga ggtccacaga ggctgcacca    540

tctccaatgt ggtgtccagc tccactggcg ctgcctctgg catcatgtcc cttgctggtc    600

ttgttttggc accatttaca gcagggacga gtctggccct tactgcagct ggggtagggc    660

tgggagcagc gtctgctgtg actgggatca ccaccagcat cgtggagcac tcatacacat    720

catcagcaga agctgaagcc agcaggctga ctgcaaccag cattgaccga ttgaaggtat    780

ttaaggaagt tatgcgtgac atcacaccca acttactttc ccttcttaat aattattacg    840

aagccacaca aaccattggg agtgaaatcc gtgccatcag gcaagccaga gccagggccc    900

gactccctgt gaccacctgg cgaatctcag ctggaagtgg tggtcaagca gagagaacga    960

ttgcaggcac cacccgggca gtgagcagag gagcccggat cctgagtgcg accacttcag   1020

gcatcttcct tgcactggat gtggtcaacc ttgtatacga gtcaaagcac ttgcatgagg   1080

gggcaaagtc tgcatctgct gaggagctga ggcggcaggc tcaggagctg gaggagaatc   1140

taatggagct cactcagatc tatcagcgtc tgaatccatg ccatacccac tgaccccaga   1200

ccagtgcagc cagcagggga ggtgagccat acacaggcca cgacaaaatg caggcatttt   1260

attaggggga taaagagggc aaggtaaagt ttatggagct gagtgttagt gactttggca   1320

tttctgtagc tgagcacagc aggggagggg ttaatgcaga tggcaagtgc accaaggaga   1380

aggcaggaat gctggagcct ggaataaggg aggagagggg actggagagt gtggggaata   1440

ggaagaagaa atttccttta gactaacgaa tatattgggg ggaggaatag aggggaggtg   1500

tgcaggaacc agcaatgaga aggccaggaa aagaaagagc tgaaaatgca gaaagccgaa   1560

gagttagaac ttttggatac agcagaagaa acagcggctc cactaccgac ctgcccccgg   1620

ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg gtcccctgcc ctgtctttcc   1680

agcatccact ctgtcttgtc ctcctggaag tgtatctcag tcagccagtg gcttcttgat   1740

gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc tttaggttat ttaggggtat   1800

atgtcccctg cttgaaccct gaaggccagg taatgagcca tggccattgt ccccagctga   1860

ggaccaggtg tctctaaaaa cccaaacatc ctggagagta tgcgagaacc taccaagaaa   1920

aacagtctca ttactcatat acagcaggca aagagacaga aaattaactg aaaagcagtt   1980

tagagactgg gggaggccgg atctctagag ccatcctgct gagtgccctg tgtgtaagtc   2040

ctaataaact cacctactca ccaagctgga cttattcgag tcattccttg gtctcctggc   2100

tcctttctcg ctttgggagc aagttcctgt ctgaagtttt tgtctgaaca gtggtaaagg   2160

tgatggtgat gatgtcagca gacagcagga ggacttgaca aatgtcagcc ctgcttgggg   2220

ccaggataca ctgagggaac gatgacattc caatgaaact ccaaattctg tattggaaaa   2280

gtcattgatt tgt                                                      2293


<210>  10410
<211>  274
<212>  PRT
<213>  Homo sapiens

<400>  10410

Met Glu Ser Leu Ser Val Thr Trp Leu Leu Ala Pro Trp Thr Gln Lys 
1               5                   10                  15


Asp Glu Gln Phe Arg Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys 
            20                  25                  30


Arg Lys Ile Gln Glu Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly 
        35                  40                  45


Ile Glu Glu Val His Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser 
    50                  55                  60


Ser Thr Gly Ala Ala Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu 
65                  70                  75                  80


Ala Pro Phe Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val 
                85                  90                  95


Gly Leu Gly Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val 
            100                 105                 110


Glu His Ser Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr 
        115                 120                 125


Ala Thr Ser Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp 
    130                 135                 140


Ile Thr Pro Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr 
145                 150                 155                 160


Gln Thr Ile Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg 
                165                 170                 175


Ala Arg Leu Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly 
            180                 185                 190


Gln Ala Glu Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly 
        195                 200                 205


Ala Arg Ile Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp 
    210                 215                 220


Val Val Asn Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys 
225                 230                 235                 240


Ser Ala Ser Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu 
                245                 250                 255


Asn Leu Met Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His 
            260                 265                 270


Thr His 



<210>  10411
<211>  2433
<212>  DNA
<213>  Homo sapiens

<400>  10411
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttgaga tgagcatcta gatagcaagg aaaaacattc    120

aatccctcaa ctgaaagtga aactgaagct gggccatgtt gtccagaggc tggttgcttt    180

tagtccaagt gctgcctccc acacctcgga tttcagccag gctgtgccac ggagggcaga    240

ggccacccag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    300

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    360

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    420

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    480

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    540

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    600

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    660

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    720

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct    780

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    840

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    900

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    960

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag   1020

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg   1080

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1140

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1200

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1260

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1320

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1380

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1440

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1500

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1560

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1620

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1680

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1740

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1800

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1860

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1920

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1980

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   2040

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   2100

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2160

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaagctgga cttattcgag   2220

tcattccttg gtctcctggc tcctttctcg ctttgggagc aagttcctgt ctgaagtttt   2280

tgtctgaaca gtggtaaagg tgatggtgat gatgtcagca gacagcagga ggacttgaca   2340

aatgtcagcc ctgcttgggg ccaggataca ctgagggaac gatgacattc caatgaaact   2400

ccaaattctg tattggaaaa gtcattgatt tgt                                2433


<210>  10412
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10412

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10413
<211>  2101
<212>  DNA
<213>  Homo sapiens

<400>  10413
actttccctt ttgggttcca gggtatatct cagagcctgg agaacgtgtc tggttattat     60

gcagatgcac ggctggaggt gggatccaca cagctcagaa cagctggatc ttgctcacac    120

tctttcaaga gaagcttcct tgggatgagg cagatgctct ctacgaagct ctgaagaagc    180

ttagaacata tgcagctatt gaggacgaat atgtgcagca gaaagatgag cagtttaggg    240

aatggttttt gaaagagttt ccccaagtca agaggaagat ccaggagtcc atagaaaagc    300

ttcgtgccct tgcaaatggt attgaagagg tccacagagg ctgcaccatc tccaatgtgg    360

tgtccagctc cactggcgct gcctctggca tcatgtccct tgctggtctt gttttggcac    420

catttacagc agggacgagt ctggccctta ctgcagctgg ggtagggctg ggagcagcgt    480

ctgctgtgac tgggatcacc accagcatcg tggagcactc atacacatca tcagcagaag    540

ctgaagccag caggctgact gcaaccagca ttgaccgatt gaaggtattt aaggaagtta    600

tgcgtgacat cacacccaac ttactttccc ttcttaataa ttattacgaa gccacacaaa    660

ccattgggag tgaaatccgt gccatcaggc aagccagagc cagggcccga ctccctgtga    720

ccacctggcg aatctcagct ggaagtggtg gtcaagcaga gagaacgatt gcaggcacca    780

cccgggcagt gagcagagga gcccggatcc tgagtgcgac cacttcaggc atcttccttg    840

cactggatgt ggtcaacctt gtatacgagt caaagcactt gcatgagggg gcaaagtctg    900

catctgctga ggagctgagg cggcaggctc aggagctgga ggagaatcta atggagctca    960

ctcagatcta tcagcgtctg aatccatgcc atacccactg accccagacc agtgcagcca   1020

gcaggggagg tgagccatac acaggccacg acaaaatgca ggcattttat tagggggata   1080

aagagggcaa ggtaaagttt atggagctga gtgttagtga ctttggcatt tctgtagctg   1140

agcacagcag gggaggggtt aatgcagatg gcaagtgcac caaggagaag gcaggaatgc   1200

tggagcctgg aataagggag gagaggggac tggagagtgt ggggaatagg aagaagaaat   1260

ttcctttaga ctaacgaata tattgggggg aggaatagag gggaggtgtg caggaaccag   1320

caatgagaag gccaggaaaa gaaagagctg aaaatgcaga aagccgaaga gttagaactt   1380

ttggatacag cagaagaaac agcggctcca ctaccgacct gcccccggtt cgatgtcctt   1440

ccaagaatga agtctttccc tggtgatggt cccctgccct gtctttccag catccactct   1500

gtcttgtcct cctggaagtg tatctcagtc agccagtggc ttcttgatga tggcggtgga   1560

ggtggtggtt gtagtgtgat ggatcccctt taggttattt aggggtatat gtcccctgct   1620

tgaaccctga aggccaggta atgagccatg gccattgtcc ccagctgagg accaggtgtc   1680

tctaaaaacc caaacatcct ggagagtatg cgagaaccta ccaagaaaaa cagtctcatt   1740

actcatatac agcaggcaaa gagacagaaa attaactgaa aagcagttta gagactgggg   1800

gaggccggat ctctagagcc atcctgctga gtgccctgtg tgtaagtcct aataaactca   1860

cctactcacc aagctggact tattcgagtc attccttggt ctcctggctc ctttctcgct   1920

ttgggagcaa gttcctgtct gaagtttttg tctgaacagt ggtaaaggtg atggtgatga   1980

tgtcagcaga cagcaggagg acttgacaaa tgtcagccct gcttggggcc aggatacact   2040

gagggaacga tgacattcca atgaaactcc aaattctgta ttggaaaagt cattgatttg   2100

t                                                                   2101


<210>  10414
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10414

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10415
<211>  2193
<212>  DNA
<213>  Homo sapiens

<400>  10415
actttcactt tcccttttgg gttccagggt atatctcaga gcctggagaa cgtgtctggt     60

tattatgcag atgcacggct ggaggtggga tccacacagc tcagaacagc tggatcttgc    120

tcacactctt tcaagagaag cttccttggg ttaagaaaaa aaacgaaccc ttccagtcag    180

gtcagtgact ggagagctcc atggaaagtc tctcagtgac ctggctgctg gcaccatgga    240

ctcagaaaag aaacgcttta ctgaagaggc caccaaatac ttccgggaga gagtcagccc    300

agtgcatctg caaatcctgc tgactaacaa tgaagcctgg aagagattcg tgactgcggc    360

tgaattgccc agggatgagg cagatgctct ctacgaagct ctgaagaagc ttagaacata    420

tgcagctatt gaggacgaat atgtgcagca gaaagatgag cagtttaggg aatggttttt    480

gaaagagttt ccccaagtca agaggaagat ccaggagtcc atagaaaagc ttcgtgccct    540

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    600

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    660

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    720

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag    780

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg    840

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat    900

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga    960

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1020

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1080

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1140

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1200

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1260

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1320

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1380

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1440

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1500

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1560

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1620

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1680

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1740

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   1800

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   1860

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   1920

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaagctgga cttattcgag   1980

tcattccttg gtctcctggc tcctttctcg ctttgggagc aagttcctgt ctgaagtttt   2040

tgtctgaaca gtggtaaagg tgatggtgat gatgtcagca gacagcagga ggacttgaca   2100

aatgtcagcc ctgcttgggg ccaggataca ctgagggaac gatgacattc caatgaaact   2160

ccaaattctg tattggaaaa gtcattgatt tgt                                2193


<210>  10416
<211>  285
<212>  PRT
<213>  Homo sapiens

<400>  10416

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala 
            100                 105                 110


Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr 
        115                 120                 125


Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp 
    130                 135                 140


Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu 
145                 150                 155                 160


Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser 
                165                 170                 175


Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val 
            180                 185                 190


Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr 
        195                 200                 205


Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser 
    210                 215                 220


Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val 
225                 230                 235                 240


Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu 
                245                 250                 255


Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu 
            260                 265                 270


Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        275                 280                 285


<210>  10417
<211>  2246
<212>  DNA
<213>  Homo sapiens

<400>  10417
gtgactttca ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct     60

ggttattatg cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct    120

tgctcacact ctttcaagag aagcttcctt gggttaagaa aaaaaacgaa cccttccagt    180

caggtcagtg actggagagc tccatggaaa gtctctcagt gacctggctg ctggcaccat    240

ggactcagaa aagaaacgct ttactgaaga ggccaccaaa tacttccggg agagagtcag    300

cccagtgcat ctgcaaatcc tgctgactaa caatgaagcc tggaagagat tcgtgactgc    360

ggctgaattg cccagggatg aggcagatgc tctctacgaa gctctgaaga agcttagaac    420

atatgcagct attgaggacg aatatgtgca gcagaaagat gagcagttta gggaatggtt    480

tttgaaagag tttccccaag tcaagaggaa gatccaggag tccatagaaa agcttccatg    540

tcccttgctg gtcttgtttt ggcaccattt acagcaggga cgagtctggc ccttactgca    600

gctggggtag ggctgggagc agcgtctgct gtgactggga tcaccaccag catcgtggag    660

cactcataca catcatcagc agaagctgaa gccagcaggc tgactgcaac cagcattgac    720

cgattgaagg tatttaagga agttatgcgt gacatcacac ccaacttact ttcccttctt    780

aataattatt acgaagccac acaaaccatt gggagtgaaa tccgtgccat caggcaagcc    840

agagccaggg cccgactccc tgtgaccacc tggcgaatct cagctggaag tggtggtcaa    900

gcagagagaa cgattgcagg caccacccgg gcagtgagca gaggagcccg gatcctgagt    960

gcgaccactt caggcatctt ccttgcactg gatgtggtca accttgtata cgagtcaaag   1020

cacttgcatg agggggcaaa gtctgcatct gctgaggagc tgaggcggca ggctcaggag   1080

ctggaggaga atctaatgga gctcactcag atctatcagc gtctgaatcc atgccatacc   1140

cactgacccc agaccagtgc agccagcagg ggaggtgagc catacacagg ccacgacaaa   1200

atgcaggcat tttattaggg ggataaagag ggcaaggtaa agtttatgga gctgagtgtt   1260

agtgactttg gcatttctgt agctgagcac agcaggggag gggttaatgc agatggcaag   1320

tgcaccaagg agaaggcagg aatgctggag cctggaataa gggaggagag gggactggag   1380

agtgtgggga ataggaagaa gaaatttcct ttagactaac gaatatattg gggggaggaa   1440

tagaggggag gtgtgcagga accagcaatg agaaggccag gaaaagaaag agctgaaaat   1500

gcagaaagcc gaagagttag aacttttgga tacagcagaa gaaacagcgg ctccactacc   1560

gacctgcccc cggttcgatg tccttccaag aatgaagtct ttccctggtg atggtcccct   1620

gccctgtctt tccagcatcc actctgtctt gtcctcctgg aagtgtatct cagtcagcca   1680

gtggcttctt gatgatggcg gtggaggtgg tggttgtagt gtgatggatc ccctttaggt   1740

tatttagggg tatatgtccc ctgcttgaac cctgaaggcc aggtaatgag ccatggccat   1800

tgtccccagc tgaggaccag gtgtctctaa aaacccaaac atcctggaga gtatgcgaga   1860

acctaccaag aaaaacagtc tcattactca tatacagcag gcaaagagac agaaaattaa   1920

ctgaaaagca gtttagagac tgggggaggc cggatctcta gagccatcct gctgagtgcc   1980

ctgtgtgtaa gtcctaataa actcacctac tcaccaagct ggacttattc gagtcattcc   2040

ttggtctcct ggctcctttc tcgctttggg agcaagttcc tgtctgaagt ttttgtctga   2100

acagtggtaa aggtgatggt gatgatgtca gcagacagca ggaggacttg acaaatgtca   2160

gccctgcttg gggccaggat acactgaggg aacgatgaca ttccaatgaa actccaaatt   2220

ctgtattgga aaagtcattg atttgt                                        2246


<210>  10418
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  10418

Met Val Phe Glu Arg Val Ser Pro Ser Gln Glu Glu Asp Pro Gly Val 
1               5                   10                  15


His Arg Lys Ala Ser Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe 
            20                  25                  30


Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly 
        35                  40                  45


Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser 
    50                  55                  60


Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser 
65                  70                  75                  80


Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro 
                85                  90                  95


Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile 
            100                 105                 110


Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu 
        115                 120                 125


Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu 
    130                 135                 140


Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile 
145                 150                 155                 160


Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn 
                165                 170                 175


Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser 
            180                 185                 190


Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met 
        195                 200                 205


Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
    210                 215                 220


<210>  10419
<211>  2673
<212>  DNA
<213>  Homo sapiens

<400>  10419
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt ggacaaaagg accctgcctt ggtgtgagag tgagggcaga    300

gggagctgga gcaagtagaa tttctctaaa taccagctgg ctggggccca ggagattaaa    360

aaacaccggg ctaggttggt cttggcattt gctgacacgc aaagggattg cagagatcca    420

gcccctccaa cctccctctg tccacaggtg gctcacattc agtcccacaa tttgctttct    480

cctcctcaag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    540

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    600

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    660

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    720

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    780

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    840

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    900

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    960

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct   1020

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat   1080

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag   1140

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc   1200

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag   1260

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg   1320

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1380

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1440

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1500

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1560

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1620

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1680

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1740

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1800

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1860

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1920

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1980

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   2040

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   2100

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   2160

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   2220

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   2280

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   2340

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2400

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaagctgga cttattcgag   2460

tcattccttg gtctcctggc tcctttctcg ctttgggagc aagttcctgt ctgaagtttt   2520

tgtctgaaca gtggtaaagg tgatggtgat gatgtcagca gacagcagga ggacttgaca   2580

aatgtcagcc ctgcttgggg ccaggataca ctgagggaac gatgacattc caatgaaact   2640

ccaaattctg tattggaaaa gtcattgatt tgt                                2673


<210>  10420
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10420

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10421
<211>  2347
<212>  DNA
<213>  Homo sapiens

<400>  10421
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt gaaaagaaac gctttactga agaggccacc aaatacttcc    300

gggagagagt cagcccagtg catctgcaaa tcctgctgac taacaatgaa gcctggaaga    360

gattcgtgac tgcggctgaa ttgcccaggg atgaggcaga tgctctctac gaagctctga    420

agaagcttag aacatatgca gctattgagg acgaatatgt gcagcagaaa gatgagcagt    480

ttagggaatg gtttttgaaa gagtttcccc aagtcaagag gaagatccag gagtccatag    540

aaaagcttcg tgcccttgca aatggtattg aagaggtcca cagaggctgc accatctcca    600

atgtggtgtc cagctccact ggcgctgcct ctggcatcat gtcccttgct ggtcttgttt    660

tggcaccatt tacagcaggg acgagtctgg cccttactgc agctggggta gggctgggag    720

cagcgtctgc tgtgactggg atcaccacca gcatcgtgga gcactcatac acatcatcag    780

cagaagctga agccagcagg ctgactgcaa ccagcattga ccgattgaag gtatttaagg    840

aagttatgcg tgacatcaca cccaacttac tttcccttct taataattat tacgaagcca    900

cacaaaccat tgggagtgaa atccgtgcca tcaggcaagc cagagccagg gcccgactcc    960

ctgtgaccac ctggcgaatc tcagctggaa gtggtggtca agcagagaga acgattgcag   1020

gcaccacccg ggcagtgagc agaggagccc ggatcctgag tgcgaccact tcaggcatct   1080

tccttgcact ggatgtggtc aaccttgtat acgagtcaaa gcacttgcat gagggggcaa   1140

agtctgcatc tgctgaggag ctgaggcggc aggctcagga gctggaggag aatctaatgg   1200

agctcactca gatctatcag cgtctgaatc catgccatac ccactgaccc cagaccagtg   1260

cagccagcag gggaggtgag ccatacacag gccacgacaa aatgcaggca ttttattagg   1320

gggataaaga gggcaaggta aagtttatgg agctgagtgt tagtgacttt ggcatttctg   1380

tagctgagca cagcagggga ggggttaatg cagatggcaa gtgcaccaag gagaaggcag   1440

gaatgctgga gcctggaata agggaggaga ggggactgga gagtgtgggg aataggaaga   1500

agaaatttcc tttagactaa cgaatatatt ggggggagga atagagggga ggtgtgcagg   1560

aaccagcaat gagaaggcca ggaaaagaaa gagctgaaaa tgcagaaagc cgaagagtta   1620

gaacttttgg atacagcaga agaaacagcg gctccactac cgacctgccc ccggttcgat   1680

gtccttccaa gaatgaagtc tttccctggt gatggtcccc tgccctgtct ttccagcatc   1740

cactctgtct tgtcctcctg gaagtgtatc tcagtcagcc agtggcttct tgatgatggc   1800

ggtggaggtg gtggttgtag tgtgatggat cccctttagg ttatttaggg gtatatgtcc   1860

cctgcttgaa ccctgaaggc caggtaatga gccatggcca ttgtccccag ctgaggacca   1920

ggtgtctcta aaaacccaaa catcctggag agtatgcgag aacctaccaa gaaaaacagt   1980

ctcattactc atatacagca ggcaaagaga cagaaaatta actgaaaagc agtttagaga   2040

ctgggggagg ccggatctct agagccatcc tgctgagtgc cctgtgtgta agtcctaata   2100

aactcaccta ctcaccaagc tggacttatt cgagtcattc cttggtctcc tggctccttt   2160

ctcgctttgg gagcaagttc ctgtctgaag tttttgtctg aacagtggta aaggtgatgg   2220

tgatgatgtc agcagacagc aggaggactt gacaaatgtc agccctgctt ggggccagga   2280

tacactgagg gaacgatgac attccaatga aactccaaat tctgtattgg aaaagtcatt   2340

gatttgt                                                             2347


<210>  10422
<211>  402
<212>  PRT
<213>  Homo sapiens

<400>  10422

Met Gly Leu Gly Gln Gly Trp Gly Trp Glu Ala Ser Cys Phe Ala Cys 
1               5                   10                  15


Leu Ile Arg Ser Cys Cys Gln Val Val Thr Phe Thr Phe Pro Phe Gly 
            20                  25                  30


Phe Gln Gly Ile Ser Gln Ser Leu Glu Asn Val Ser Gly Tyr Tyr Ala 
        35                  40                  45


Asp Ala Arg Leu Glu Val Gly Ser Thr Gln Leu Arg Thr Ala Gly Ser 
    50                  55                  60


Cys Ser His Ser Phe Lys Arg Ser Phe Leu Glu Lys Lys Arg Phe Thr 
65                  70                  75                  80


Glu Glu Ala Thr Lys Tyr Phe Arg Glu Arg Val Ser Pro Val His Leu 
                85                  90                  95


Gln Ile Leu Leu Thr Asn Asn Glu Ala Trp Lys Arg Phe Val Thr Ala 
            100                 105                 110


Ala Glu Leu Pro Arg Asp Glu Ala Asp Ala Leu Tyr Glu Ala Leu Lys 
        115                 120                 125


Lys Leu Arg Thr Tyr Ala Ala Ile Glu Asp Glu Tyr Val Gln Gln Lys 
    130                 135                 140


Asp Glu Gln Phe Arg Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys 
145                 150                 155                 160


Arg Lys Ile Gln Glu Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly 
                165                 170                 175


Ile Glu Glu Val His Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser 
            180                 185                 190


Ser Thr Gly Ala Ala Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu 
        195                 200                 205


Ala Pro Phe Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val 
    210                 215                 220


Gly Leu Gly Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val 
225                 230                 235                 240


Glu His Ser Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr 
                245                 250                 255


Ala Thr Ser Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp 
            260                 265                 270


Ile Thr Pro Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr 
        275                 280                 285


Gln Thr Ile Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg 
    290                 295                 300


Ala Arg Leu Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly 
305                 310                 315                 320


Gln Ala Glu Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly 
                325                 330                 335


Ala Arg Ile Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp 
            340                 345                 350


Val Val Asn Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys 
        355                 360                 365


Ser Ala Ser Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu 
    370                 375                 380


Asn Leu Met Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His 
385                 390                 395                 400


Thr His 



<210>  10423
<211>  2444
<212>  DNA
<213>  Homo sapiens

<400>  10423
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt gggttaagaa aaaaaacgaa cccttccagt caggtcagtg    300

actggagagc tccatggaaa gtctctcagt gacctggctg ctggcaccat ggactcagaa    360

aagaaacgct ttactgaaga ggccaccaaa tacttccggg agagagtcag cccagtgcat    420

ctgcaaatcc tgctgactaa caatgaagcc tggaagagat tcgtgactgc ggctgaattg    480

cccagggatg aggcagatgc tctctacgaa gctctgaaga agcttagaac atatgcagct    540

attgaggacg aatatgtgca gcagaaagat gagcagttta gggaatggtt tttgaaagag    600

tttccccaag tcaagaggaa gatccaggag tccatagaaa agcttcgtgc ccttgcaaat    660

ggtattgaag aggtccacag aggctgcacc atctccaatg tggtgtccag ctccactggc    720

gctgcctctg gcatcatgtc ccttgctggt cttgttttgg caccatttac agcagggacg    780

agtctggccc ttactgcagc tggggtaggg ctgggagcag cgtctgctgt gactgggatc    840

accaccagca tcgtggagca ctcatacaca tcatcagcag aagctgaagc cagcaggctg    900

actgcaacca gcattgaccg attgaaggta tttaaggaag ttatgcgtga catcacaccc    960

aacttacttt cccttcttaa taattattac gaagccacac aaaccattgg gagtgaaatc   1020

cgtgccatca ggcaagccag agccagggcc cgactccctg tgaccacctg gcgaatctca   1080

gctggaagtg gtggtcaagc agagagaacg attgcaggca ccacccgggc agtgagcaga   1140

ggagcccgga tcctgagtgc gaccacttca ggcatcttcc ttgcactgga tgtggtcaac   1200

cttgtatacg agtcaaagca cttgcatgag ggggcaaagt ctgcatctgc tgaggagctg   1260

aggcggcagg ctcaggagct ggaggagaat ctaatggagc tcactcagat ctatcagcgt   1320

ctgaatccat gccataccca ctgaccccag accagtgcag ccagcagggg aggtgagcca   1380

tacacaggcc acgacaaaat gcaggcattt tattaggggg ataaagaggg caaggtaaag   1440

tttatggagc tgagtgttag tgactttggc atttctgtag ctgagcacag caggggaggg   1500

gttaatgcag atggcaagtg caccaaggag aaggcaggaa tgctggagcc tggaataagg   1560

gaggagaggg gactggagag tgtggggaat aggaagaaga aatttccttt agactaacga   1620

atatattggg gggaggaata gaggggaggt gtgcaggaac cagcaatgag aaggccagga   1680

aaagaaagag ctgaaaatgc agaaagccga agagttagaa cttttggata cagcagaaga   1740

aacagcggct ccactaccga cctgcccccg gttcgatgtc cttccaagaa tgaagtcttt   1800

ccctggtgat ggtcccctgc cctgtctttc cagcatccac tctgtcttgt cctcctggaa   1860

gtgtatctca gtcagccagt ggcttcttga tgatggcggt ggaggtggtg gttgtagtgt   1920

gatggatccc ctttaggtta tttaggggta tatgtcccct gcttgaaccc tgaaggccag   1980

gtaatgagcc atggccattg tccccagctg aggaccaggt gtctctaaaa acccaaacat   2040

cctggagagt atgcgagaac ctaccaagaa aaacagtctc attactcata tacagcaggc   2100

aaagagacag aaaattaact gaaaagcagt ttagagactg ggggaggccg gatctctaga   2160

gccatcctgc tgagtgccct gtgtgtaagt cctaataaac tcacctactc accaagctgg   2220

acttattcga gtcattcctt ggtctcctgg ctcctttctc gctttgggag caagttcctg   2280

tctgaagttt ttgtctgaac agtggtaaag gtgatggtga tgatgtcagc agacagcagg   2340

aggacttgac aaatgtcagc cctgcttggg gccaggatac actgagggaa cgatgacatt   2400

ccaatgaaac tccaaattct gtattggaaa agtcattgat ttgt                    2444


<210>  10424
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10424

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10425
<211>  2557
<212>  DNA
<213>  Homo sapiens

<400>  10425
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt ggacaaaagg accctgcctt ggtgtgagag tgagggcaga    300

gggagctgga gcaagtagaa tttctctaaa taccagctgg ctggggccca ggagattaaa    360

aaacaccggg ctagggttaa gaaaaaaaac gaacccttcc agtcaggtca gtgactggag    420

agctccatgg aaagtctctc agtgacctgg ctgctggcac catggactca gaaaagaaac    480

gctttactga agaggccacc aaatacttcc gggagagagt cagcccagtg catctgcaaa    540

tcctgctgac taacaatgaa gcctggaaga gattcgtgac tgcggctgaa ttgcccaggg    600

atgaggcaga tgctctctac gaagctctga agaagcttag aacatatgca gctattgagg    660

acgaatatgt gcagcagaaa gatgagcagt ttagggaatg gtttttgaaa gagtttcccc    720

aagtcaagag gaagatccag gagtccatag aaaagcttcg tgcccttgca aatggtattg    780

aagaggtcca cagaggctgc accatctcca atgtggtgtc cagctccact ggcgctgcct    840

ctggcatcat gtcccttgct ggtcttgttt tggcaccatt tacagcaggg acgagtctgg    900

cccttactgc agctggggta gggctgggag cagcgtctgc tgtgactggg atcaccacca    960

gcatcgtgga gcactcatac acatcatcag cagaagctga agccagcagg ctgactgcaa   1020

ccagcattga ccgattgaag gtatttaagg aagttatgcg tgacatcaca cccaacttac   1080

tttcccttct taataattat tacgaagcca cacaaaccat tgggagtgaa atccgtgcca   1140

tcaggcaagc cagagccagg gcccgactcc ctgtgaccac ctggcgaatc tcagctggaa   1200

gtggtggtca agcagagaga acgattgcag gcaccacccg ggcagtgagc agaggagccc   1260

ggatcctgag tgcgaccact tcaggcatct tccttgcact ggatgtggtc aaccttgtat   1320

acgagtcaaa gcacttgcat gagggggcaa agtctgcatc tgctgaggag ctgaggcggc   1380

aggctcagga gctggaggag aatctaatgg agctcactca gatctatcag cgtctgaatc   1440

catgccatac ccactgaccc cagaccagtg cagccagcag gggaggtgag ccatacacag   1500

gccacgacaa aatgcaggca ttttattagg gggataaaga gggcaaggta aagtttatgg   1560

agctgagtgt tagtgacttt ggcatttctg tagctgagca cagcagggga ggggttaatg   1620

cagatggcaa gtgcaccaag gagaaggcag gaatgctgga gcctggaata agggaggaga   1680

ggggactgga gagtgtgggg aataggaaga agaaatttcc tttagactaa cgaatatatt   1740

ggggggagga atagagggga ggtgtgcagg aaccagcaat gagaaggcca ggaaaagaaa   1800

gagctgaaaa tgcagaaagc cgaagagtta gaacttttgg atacagcaga agaaacagcg   1860

gctccactac cgacctgccc ccggttcgat gtccttccaa gaatgaagtc tttccctggt   1920

gatggtcccc tgccctgtct ttccagcatc cactctgtct tgtcctcctg gaagtgtatc   1980

tcagtcagcc agtggcttct tgatgatggc ggtggaggtg gtggttgtag tgtgatggat   2040

cccctttagg ttatttaggg gtatatgtcc cctgcttgaa ccctgaaggc caggtaatga   2100

gccatggcca ttgtccccag ctgaggacca ggtgtctcta aaaacccaaa catcctggag   2160

agtatgcgag aacctaccaa gaaaaacagt ctcattactc atatacagca ggcaaagaga   2220

cagaaaatta actgaaaagc agtttagaga ctgggggagg ccggatctct agagccatcc   2280

tgctgagtgc cctgtgtgta agtcctaata aactcaccta ctcaccaagc tggacttatt   2340

cgagtcattc cttggtctcc tggctccttt ctcgctttgg gagcaagttc ctgtctgaag   2400

tttttgtctg aacagtggta aaggtgatgg tgatgatgtc agcagacagc aggaggactt   2460

gacaaatgtc agccctgctt ggggccagga tacactgagg gaacgatgac attccaatga   2520

aactccaaat tctgtattgg aaaagtcatt gatttgt                            2557


<210>  10426
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10426

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10427
<211>  3856
<212>  DNA
<213>  Homo sapiens

<400>  10427
actctgggga aaggagggta caaccacatg taaattttat tataatgatg gtataatgaa     60

cttggggtga cctgagggca tgtttttgtg ttactgggca tgtgcccctt taggagactt    120

ccacctgtgc cttactttct ctttctttgg gatgtgctgg ccacagactt taccaaaaac    180

tccatccatt aggatggcat taggacggtt ctggggctaa acttaggtgg gccaggggct    240

gtttcactgt cagcctttct actctctttt cttacccact cctagctgct aatgtctatt    300

taactaccta atatttcccc ctttagagaa aaaaagccaa atttttgggt agatcggtga    360

caattaatct ggctacttcc tgctgacaag aggcagtggt aataattggg ttctcttttt    420

tgctctcttg tagctggtag gttgggcaga gaaaagtggt ggccatccaa ggggcccacg    480

tagatatcag acatggttga gacctcgcgg taaccttgtg tagaatcatt tggagtttta    540

tggattctag gtgggaagaa acaaaacaac cttgtaaatc aaatgagcat cgtttgaaag    600

ctataagttg tataaagctg ttttaggacc aagaaagggg gctaaccagg aaaaccagga    660

ccagttgtta aatttccacc agtcaaagcc tcctgaaact ctgttttcca ttaacttgtt    720

ggccctgtct gtaatttttt taagttggtt tgcactttac ctgattggtt gatgaaaaca    780

gcaatgttta tcaagtgttg cacaagctcc cccttgattg gctgtgagca aattaaaagc    840

tcatcaattt cataagacta tgcttgctaa tgaagcaatt tgttctgaaa gggtattgac    900

ctggttagtt agattaataa tttgttgagt aatttttaag aagagtttct gggcagtaaa    960

aatggagtta aggaggtcct ccagttcccg tgccaatacc agccagaacg ccaattatag   1020

tcagtgctgt taaaactcct ctttcagttt taccagattg agcgtgtata gggaggggaa   1080

tgctatcgat aagagtgagt ttggggatga tgtaaactag ggccaaatcc ccgtttaatt   1140

agcagacaag cagagatatg ccttgtttct atacaaaaat gtgatttgtc atgttaagac   1200

aaatatcaac agtgatacta aagtagggtt tttccatgct gtgtaagtct gctttaatac   1260

cctcagaagt ggaagtcaag gctagttcat gtaatggggg aacacaggca gtacttgaca   1320

gaatgaaaga ggaatcaaaa gcccaattag aggaaggagt gatgggatcc caaccaatat   1380

tgtgaaatta tggggagctg cagttttttg caatgatttt gcccgaagtt gtgagactga   1440

aaccagaagt tgttatgttt aaaatgatat tctggtgtgg gtctggggaa aagggtagat   1500

ccagaatagc tggcttcttt ccacatagtg gttctgttgg ggggcttggg aaatgaataa   1560

aacacaaaga agaattagaa tatcaggtga aggtagcagg tgctcctggc agaagaaccc   1620

acataaggaa gtgtccagaa gccacacagg gtatatctca gagcctggag aacgtgtctg   1680

gttattatgc agatgcacgg ctggaggtgg gatccacaca gctcagaaca gctggatctt   1740

gctcacactc tttcaagaga agcttccttg aaaagaaacg ctttactgaa gaggccacca   1800

aatacttccg ggagagagtc agcccagtgc atctgcaaat cctgctgact aacaatgaag   1860

cctggaagag attcgtgact gcggctgaat tgcccaggga tgaggcagat gctctctacg   1920

aagctctgaa gaagcttaga acatatgcag ctattgagga cgaatatgtg cagcagaaag   1980

atgagcagtt tagggaatgg tttttgaaag agtttcccca agtcaagagg aagatccagg   2040

agtccataga aaagcttcgt gcccttgcaa atggtattga agaggtccac agaggctgca   2100

ccatctccaa tgtggtgtcc agctccactg gcgctgcctc tggcatcatg tcccttgctg   2160

gtcttgtttt ggcaccattt acagcaggga cgagtctggc ccttactgca gctggggtag   2220

ggctgggagc agcgtctgct gtgactggga tcaccaccag catcgtggag cactcataca   2280

catcatcagc agaagctgaa gccagcaggc tgactgcaac cagcattgac cgattgaagg   2340

tatttaagga agttatgcgt gacatcacac ccaacttact ttcccttctt aataattatt   2400

acgaagccac acaaaccatt gggagtgaaa tccgtgccat caggcaagcc agagccaggg   2460

cccgactccc tgtgaccacc tggcgaatct cagctggaag tggtggtcaa gcagagagaa   2520

cgattgcagg caccacccgg gcagtgagca gaggagcccg gatcctgagt gcgaccactt   2580

caggcatctt ccttgcactg gatgtggtca accttgtata cgagtcaaag cacttgcatg   2640

agggggcaaa gtctgcatct gctgaggagc tgaggcggca ggctcaggag ctggaggaga   2700

atctaatgga gctcactcag atctatcagc gtctgaatcc atgccatacc cactgacccc   2760

agaccagtgc agccagcagg ggaggtgagc catacacagg ccacgacaaa atgcaggcat   2820

tttattaggg ggataaagag ggcaaggtaa agtttatgga gctgagtgtt agtgactttg   2880

gcatttctgt agctgagcac agcaggggag gggttaatgc agatggcaag tgcaccaagg   2940

agaaggcagg aatgctggag cctggaataa gggaggagag gggactggag agtgtgggga   3000

ataggaagaa gaaatttcct ttagactaac gaatatattg gggggaggaa tagaggggag   3060

gtgtgcagga accagcaatg agaaggccag gaaaagaaag agctgaaaat gcagaaagcc   3120

gaagagttag aacttttgga tacagcagaa gaaacagcgg ctccactacc gacctgcccc   3180

cggttcgatg tccttccaag aatgaagtct ttccctggtg atggtcccct gccctgtctt   3240

tccagcatcc actctgtctt gtcctcctgg aagtgtatct cagtcagcca gtggcttctt   3300

gatgatggcg gtggaggtgg tggttgtagt gtgatggatc ccctttaggt tatttagggg   3360

tatatgtccc ctgcttgaac cctgaaggcc aggtaatgag ccatggccat tgtccccagc   3420

tgaggaccag gtgtctctaa aaacccaaac atcctggaga gtatgcgaga acctaccaag   3480

aaaaacagtc tcattactca tatacagcag gcaaagagac agaaaattaa ctgaaaagca   3540

gtttagagac tgggggaggc cggatctcta gagccatcct gctgagtgcc ctgtgtgtaa   3600

gtcctaataa actcacctac tcaccaagct ggacttattc gagtcattcc ttggtctcct   3660

ggctcctttc tcgctttggg agcaagttcc tgtctgaagt ttttgtctga acagtggtaa   3720

aggtgatggt gatgatgtca gcagacagca ggaggacttg acaaatgtca gccctgcttg   3780

gggccaggat acactgaggg aacgatgaca ttccaatgaa actccaaatt ctgtattgga   3840

aaagtcattg atttgt                                                   3856


<210>  10428
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  10428

Met Asn Lys Thr Gln Arg Arg Ile Arg Ile Ser Gly Glu Gly Ser Arg 
1               5                   10                  15


Cys Ser Trp Gln Lys Asn Pro His Lys Glu Val Ser Arg Ser His Thr 
            20                  25                  30


Gly Tyr Ile Ser Glu Pro Gly Glu Arg Val Trp Leu Leu Cys Arg Cys 
        35                  40                  45


Thr Ala Gly Gly Gly Ile His Thr Ala Gln Asn Ser Trp Ile Leu Leu 
    50                  55                  60


Thr Leu Phe Gln Glu Lys Leu Pro 
65                  70


<210>  10429
<211>  3793
<212>  DNA
<213>  Homo sapiens

<400>  10429
actctgggga aaggagggta caaccacatg taaattttat tataatgatg gtataatgaa     60

cttggggtga cctgagggca tgtttttgtg ttactgggca tgtgcccctt taggagactt    120

ccacctgtgc cttactttct ctttctttgg gatgtgctgg ccacagactt taccaaaaac    180

tccatccatt aggatggcat taggacggtt ctggggctaa acttaggtgg gccaggggct    240

gtttcactgt cagcctttct actctctttt cttacccact cctagctgct aatgtctatt    300

taactaccta atatttcccc ctttagagaa aaaaagccaa atttttgggt agatcggtga    360

caattaatct ggctacttcc tgctgacaag aggcagtggt aataattggg ttctcttttt    420

tgctctcttg tagctggtag gttgggcaga gaaaagtggt ggccatccaa ggggcccacg    480

tagatatcag acatggttga gacctcgcgg taaccttgtg tagaatcatt tggagtttta    540

tggattctag gtgggaagaa acaaaacaac cttgtaaatc aaatgagcat cgtttgaaag    600

ctataagttg tataaagctg ttttaggacc aagaaagggg gctaaccagg aaaaccagga    660

ccagttgtta aatttccacc agtcaaagcc tcctgaaact ctgttttcca ttaacttgtt    720

ggccctgtct gtaatttttt taagttggtt tgcactttac ctgattggtt gatgaaaaca    780

gcaatgttta tcaagtgttg cacaagctcc cccttgattg gctgtgagca aattaaaagc    840

tcatcaattt cataagacta tgcttgctaa tgaagcaatt tgttctgaaa gggtattgac    900

ctggttagtt agattaataa tttgttgagt aatttttaag aagagtttct gggcagtaaa    960

aatggagtta aggaggtcct ccagttcccg tgccaatacc agccagaacg ccaattatag   1020

tcagtgctgt taaaactcct ctttcagttt taccagattg agcgtgtata gggaggggaa   1080

tgctatcgat aagagtgagt ttggggatga tgtaaactag ggccaaatcc ccgtttaatt   1140

agcagacaag cagagatatg ccttgtttct atacaaaaat gtgatttgtc atgttaagac   1200

aaatatcaac agtgatacta aagtagggtt tttccatgct gtgtaagtct gctttaatac   1260

cctcagaagt ggaagtcaag gctagttcat gtaatggggg aacacaggca gtacttgaca   1320

gaatgaaaga ggaatcaaaa gcccaattag aggaaggagt gatgggatcc caaccaatat   1380

tgtgaaatta tggggagctg cagttttttg caatgatttt gcccgaagtt gtgagactga   1440

aaccagaagt tgttatgttt aaaatgatat tctggtgtgg gtctggggaa aagggtagat   1500

ccagaatagc tggcttcttt ccacatagtg gttctgttgg ggggcttggg aaatgaataa   1560

aacacaaaga agaattagaa tatcagggta tatctcagag cctggagaac gtgtctggtt   1620

attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct   1680

cacactcttt caagagaagc ttccttgaaa agaaacgctt tactgaagag gccaccaaat   1740

acttccggga gagagtcagc ccagtgcatc tgcaaatcct gctgactaac aatgaagcct   1800

ggaagagatt cgtgactgcg gctgaattgc ccagggatga ggcagatgct ctctacgaag   1860

ctctgaagaa gcttagaaca tatgcagcta ttgaggacga atatgtgcag cagaaagatg   1920

agcagtttag ggaatggttt ttgaaagagt ttccccaagt caagaggaag atccaggagt   1980

ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga ggtccacaga ggctgcacca   2040

tctccaatgt ggtgtccagc tccactggcg ctgcctctgg catcatgtcc cttgctggtc   2100

ttgttttggc accatttaca gcagggacga gtctggccct tactgcagct ggggtagggc   2160

tgggagcagc gtctgctgtg actgggatca ccaccagcat cgtggagcac tcatacacat   2220

catcagcaga agctgaagcc agcaggctga ctgcaaccag cattgaccga ttgaaggtat   2280

ttaaggaagt tatgcgtgac atcacaccca acttactttc ccttcttaat aattattacg   2340

aagccacaca aaccattggg agtgaaatcc gtgccatcag gcaagccaga gccagggccc   2400

gactccctgt gaccacctgg cgaatctcag ctggaagtgg tggtcaagca gagagaacga   2460

ttgcaggcac cacccgggca gtgagcagag gagcccggat cctgagtgcg accacttcag   2520

gcatcttcct tgcactggat gtggtcaacc ttgtatacga gtcaaagcac ttgcatgagg   2580

gggcaaagtc tgcatctgct gaggagctga ggcggcaggc tcaggagctg gaggagaatc   2640

taatggagct cactcagatc tatcagcgtc tgaatccatg ccatacccac tgaccccaga   2700

ccagtgcagc cagcagggga ggtgagccat acacaggcca cgacaaaatg caggcatttt   2760

attaggggga taaagagggc aaggtaaagt ttatggagct gagtgttagt gactttggca   2820

tttctgtagc tgagcacagc aggggagggg ttaatgcaga tggcaagtgc accaaggaga   2880

aggcaggaat gctggagcct ggaataaggg aggagagggg actggagagt gtggggaata   2940

ggaagaagaa atttccttta gactaacgaa tatattgggg ggaggaatag aggggaggtg   3000

tgcaggaacc agcaatgaga aggccaggaa aagaaagagc tgaaaatgca gaaagccgaa   3060

gagttagaac ttttggatac agcagaagaa acagcggctc cactaccgac ctgcccccgg   3120

ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg gtcccctgcc ctgtctttcc   3180

agcatccact ctgtcttgtc ctcctggaag tgtatctcag tcagccagtg gcttcttgat   3240

gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc tttaggttat ttaggggtat   3300

atgtcccctg cttgaaccct gaaggccagg taatgagcca tggccattgt ccccagctga   3360

ggaccaggtg tctctaaaaa cccaaacatc ctggagagta tgcgagaacc taccaagaaa   3420

aacagtctca ttactcatat acagcaggca aagagacaga aaattaactg aaaagcagtt   3480

tagagactgg gggaggccgg atctctagag ccatcctgct gagtgccctg tgtgtaagtc   3540

ctaataaact cacctactca ccaagctgga cttattcgag tcattccttg gtctcctggc   3600

tcctttctcg ctttgggagc aagttcctgt ctgaagtttt tgtctgaaca gtggtaaagg   3660

tgatggtgat gatgtcagca gacagcagga ggacttgaca aatgtcagcc ctgcttgggg   3720

ccaggataca ctgagggaac gatgacattc caatgaaact ccaaattctg tattggaaaa   3780

gtcattgatt tgt                                                      3793


<210>  10430
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  10430

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Lys Arg Asn Ala 
            20                  25                  30


Leu Leu Lys Arg Pro Pro Asn Thr Ser Gly Arg Glu Ser Ala Gln Cys 
        35                  40                  45


Ile Cys Lys Ser Cys 
    50


<210>  10431
<211>  2220
<212>  DNA
<213>  Homo sapiens

<400>  10431
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt gggttaagaa aaaaaacgaa cccttccagt caggtcagtg    300

actggagagc tccatggaaa gtctctcagt gacctggctg ctggcaccat ggactcagaa    360

aagaaacgct ttactgaaga ggccaccaaa tacttccggg agagagtcag cccagtgcat    420

ctgcaaatcc tgctgactaa caatgaagcc tggaagagat tcgtgactgc ggctgaattg    480

cccagggatg aggcagatgc tctctacgaa gctctgaaga agcttagaac atatgcagct    540

attgaggacg aatatgtgca gcagaaagat gagcagttta gggaatggtt tttgaaagag    600

tttccccaag tcaagaggaa gatccaggag tccatagaaa agcttcgtgc ccttgcaaat    660

ggtattgaag aggtccacag aggctgcacc atctccaatg tggtgtccag ctccactggc    720

gctgcctctg gcatcatgtc ccttgctggt cttgttttgg caccatttac agcagggacg    780

agtctggccc ttactgcagc tggggtaggg ctgggagcag cgtctgctgt gactgggatc    840

accaccagca tcgtggagca ctcatacaca tcatcagcag aagctgaagc cagcaggctg    900

actgcaacca gcattgaccg attgaaggta tttaaggaag ttatgcgtga catcacaccc    960

aacttacttt cccttcttaa taattattac gaagccacac aaaccattgg gagtgaaatc   1020

cgtgccatca ggcaagccag agccagggcc cgactccctg tgaccacctg gcgaatctca   1080

gctggaagtg gtggtcaagc agagagaacg attgcaggca ccacccgggc agtgagcaga   1140

ggagcccgga tcctgagtgc gaccacttca ggcatcttcc ttgcactgga tgtggtcaac   1200

cttgtatacg agtcaaagca cttgcatgag ggggcaaagt ctgcatctgc tgaggagctg   1260

aggcggcagg ctcaggagct ggaggagaat ctaatggagc tcactcagat ctatcagcgt   1320

ctgaatccat gccataccca ctgaccccag accagtgcag ccagcagggg aggtgagcca   1380

tacacaggcc acgacaaaat gcaggcattt tattaggggg ataaagaggg caaggtaaag   1440

tttatggagc tgagtgttag tgactttggc atttctgtag ctgagcacag caggggaggg   1500

gttaatgcag atggcaagtg caccaaggag aaggcaggaa tgctggagcc tggaataagg   1560

gaggagaggg gactggagag tgtggggaat aggaagaaga aatttccttt agactaacga   1620

atatattggg gggaggaata gaggggaggt gtgcaggaac cagcaatgag aaggccagga   1680

aaagaaagag ctgaaaatgc agaaagccga agagttagaa cttttggata cagcagaaga   1740

aacagcggct ccactaccga cctgcccccg gttcgatgtc cttccaagaa tgaagtcttt   1800

ccctggtgat ggtcccctgc cctgtctttc cagcatccac tctgtcttgt cctcctggaa   1860

gtgtatctca gtcagccagt ggcttcttga tgatggcggt ggaggtggtg gttgtagtgt   1920

gatggatccc ctttaggtta tttaggggta tatgtcccct gcttgaaccc tgaaggccag   1980

gtaatgagcc atggccattg tccccagctg aggaccaggt gtctctaaaa acccaaacat   2040

cctggagagt atgcgagaac ctaccaagaa aaacagtctc attactcata tacagcaggc   2100

aaagagacag aaaattaact gaaaagcagt ttagagactg ggggaggccg gatctctaga   2160

gccatcctgc tgagtgccct gtgtgtaagt cctaataaac tcacctactc accaagctgg   2220


<210>  10432
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10432

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10433
<211>  2137
<212>  DNA
<213>  Homo sapiens

<400>  10433
tagacaccag tcctgtagga ttagggccct acccttacga ctctctttaa attaatgact     60

tccttaaagg ctcaatctcc aaatatagtt actggggttt agggtctcag tatatgaatt    120

tggagggcac acaactcagt ctatagcact gatgcctcca tcaaaaatac cccatgtgac    180

agctggttga ggaggattaa cctcgaacca ccttattctc aatgccattt aggctgtagc    240

acactttctt ccaatcttat gctttttgtt tccaagtaga aaagaaacgc tttactgaag    300

aggccaccaa atacttccgg gagagagtca gcccagtgca tctgcaaatc ctgctgacta    360

acaatgaagc ctggaagaga ttcgtgactg cggctgaatt gcccagggat gaggcagatg    420

ctctctacga agctctgaag aagcttagaa catatgcagc tattgaggac gaatatgtgc    480

agcagaaaga tgagcagttt agggaatggt ttttgaaaga gtttccccaa gtcaagagga    540

agatccagga gtccatagaa aagcttcgtg cccttgcaaa tggtattgaa gaggtccaca    600

gaggctgcac catctccaat gtggtgtcca gctccactgg cgctgcctct ggcatcatgt    660

cccttgctgg tcttgttttg gcaccattta cagcagggac gagtctggcc cttactgcag    720

ctggggtagg gctgggagca gcgtctgctg tgactgggat caccaccagc atcgtggagc    780

actcatacac atcatcagca gaagctgaag ccagcaggct gactgcaacc agcattgacc    840

gattgaaggt atttaaggaa gttatgcgtg acatcacacc caacttactt tcccttctta    900

ataattatta cgaagccaca caaaccattg ggagtgaaat ccgtgccatc aggcaagcca    960

gagccagggc ccgactccct gtgaccacct ggcgaatctc agctggaagt ggtggtcaag   1020

cagagagaac gattgcaggc accacccggg cagtgagcag aggagcccgg atcctgagtg   1080

cgaccacttc aggcatcttc cttgcactgg atgtggtcaa ccttgtatac gagtcaaagc   1140

acttgcatga gggggcaaag tctgcatctg ctgaggagct gaggcggcag gctcaggagc   1200

tggaggagaa tctaatggag ctcactcaga tctatcagcg tctgaatcca tgccataccc   1260

actgacccca gaccagtgca gccagcaggg gaggtgagcc atacacaggc cacgacaaaa   1320

tgcaggcatt ttattagggg gataaagagg gcaaggtaaa gtttatggag ctgagtgtta   1380

gtgactttgg catttctgta gctgagcaca gcaggggagg ggttaatgca gatggcaagt   1440

gcaccaagga gaaggcagga atgctggagc ctggaataag ggaggagagg ggactggaga   1500

gtgtggggaa taggaagaag aaatttcctt tagactaacg aatatattgg ggggaggaat   1560

agaggggagg tgtgcaggaa ccagcaatga gaaggccagg aaaagaaaga gctgaaaatg   1620

cagaaagccg aagagttaga acttttggat acagcagaag aaacagcggc tccactaccg   1680

acctgccccc ggttcgatgt ccttccaaga atgaagtctt tccctggtga tggtcccctg   1740

ccctgtcttt ccagcatcca ctctgtcttg tcctcctgga agtgtatctc agtcagccag   1800

tggcttcttg atgatggcgg tggaggtggt ggttgtagtg tgatggatcc cctttaggtt   1860

atttaggggt atatgtcccc tgcttgaacc ctgaaggcca ggtaatgagc catggccatt   1920

gtccccagct gaggaccagg tgtctctaaa aacccaaaca tcctggagag tatgcgagaa   1980

cctaccaaga aaaacagtct cattactcat atacagcagg caaagagaca gaaaattaac   2040

tgaaaagcag tttagagact gggggaggcc ggatctctag agccatcctg ctgagtgccc   2100

tgtgtgtaag tcctaataaa ctcacctact caccaag                            2137


<210>  10434
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10434

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10435
<211>  2092
<212>  DNA
<213>  Homo sapiens

<400>  10435
gatttcagcc aggctgtgcc acggagggca gaggccaccc aggtcagtca taggggatgc     60

agctgggaac accgcagggt ccctgccgga tgctcagagt ttaacgggga gacagaggcc    120

caaagagcca cacagagggt taagaaaaaa aacgaaccct tccagtcagg tcagtgactg    180

gagagctcca tggaaagtct ctcagtgacc tggctgctgg caccatggac tcagaaaaga    240

aacgctttac tgaagaggcc accaaatact tccgggagag agtcagccca gtgcatctgc    300

aaatcctgct gactaacaat gaagcctgga agagattcgt gactgcggct gaattgccca    360

gggatgaggc agatgctctc tacgaagctc tgaagaagct tagaacatat gcagctattg    420

aggacgaata tgtgcagcag aaagatgagc agtttaggga atggtttttg aaagagtttc    480

cccaagtcaa gaggaagatc caggagtcca tagaaaagct tcgtgccctt gcaaatggta    540

ttgaagaggt ccacagaggc tgcaccatct ccaatgtggt gtccagctcc actggcgctg    600

cctctggcat catgtccctt gctggtcttg ttttggcacc atttacagca gggacgagtc    660

tggcccttac tgcagctggg gtagggctgg gagcagcgtc tgctgtgact gggatcacca    720

ccagcatcgt ggagcactca tacacatcat cagcagaagc tgaagccagc aggctgactg    780

caaccagcat tgaccgattg aaggtattta aggaagttat gcgtgacatc acacccaact    840

tactttccct tcttaataat tattacgaag ccacacaaac cattgggagt gaaatccgtg    900

ccatcaggca agccagagcc agggcccgac tccctgtgac cacctggcga atctcagctg    960

gaagtggtgg tcaagcagag agaacgattg caggcaccac ccgggcagtg agcagaggag   1020

cccggatcct gagtgcgacc acttcaggca tcttccttgc actggatgtg gtcaaccttg   1080

tatacgagtc aaagcacttg catgaggggg caaagtctgc atctgctgag gagctgaggc   1140

ggcaggctca ggagctggag gagaatctaa tggagctcac tcagatctat cagcgtctga   1200

atccatgcca tacccactga ccccagacca gtgcagccag caggggaggt gagccataca   1260

caggccacga caaaatgcag gcattttatt agggggataa agagggcaag gtaaagttta   1320

tggagctgag tgttagtgac tttggcattt ctgtagctga gcacagcagg ggaggggtta   1380

atgcagatgg caagtgcacc aaggagaagg caggaatgct ggagcctgga ataagggagg   1440

agaggggact ggagagtgtg gggaatagga agaagaaatt tcctttagac taacgaatat   1500

attgggggga ggaatagagg ggaggtgtgc aggaaccagc aatgagaagg ccaggaaaag   1560

aaagagctga aaatgcagaa agccgaagag ttagaacttt tggatacagc agaagaaaca   1620

gcggctccac taccgacctg cccccggttc gatgtccttc caagaatgaa gtctttccct   1680

ggtgatggtc ccctgccctg tctttccagc atccactctg tcttgtcctc ctggaagtgt   1740

atctcagtca gccagtggct tcttgatgat ggcggtggag gtggtggttg tagtgtgatg   1800

gatccccttt aggttattta ggggtatatg tcccctgctt gaaccctgaa ggccaggtaa   1860

tgagccatgg ccattgtccc cagctgagga ccaggtgtct ctaaaaaccc aaacatcctg   1920

gagagtatgc gagaacctac caagaaaaac agtctcatta ctcatataca gcaggcaaag   1980

agacagaaaa ttaactgaaa agcagtttag agactggggg aggccggatc tctagagcca   2040

tcctgctgag tgccctgtgt gtaagtccta ataaactcac ctactcacca ag           2092


<210>  10436
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10436

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10437
<211>  1951
<212>  DNA
<213>  Homo sapiens

<400>  10437
gttgtccaga ggctggttgc ttttagtcca agtgctgcct cccacacctc ggatttcagc     60

caggctgtgc cacggagggc agaggccacc cagaaaagaa acgctttact gaagaggcca    120

ccaaatactt ccgggagaga gtcagcccag tgcatctgca aatcctgctg actaacaatg    180

aagcctggaa gagattcgtg actgcggctg aattgcccag ggatgaggca gatgctctct    240

acgaagctct gaagaagctt agaacatatg cagctattga ggacgaatat gtgcagcaga    300

aagatgagca gtttagggaa tggtttttga aagagtttcc ccaagtcaag aggaagatcc    360

aggagtccat agaaaagctt cgtgcccttg caaatggtat tgaagaggtc cacagaggct    420

gcaccatctc caatgtggtg tccagctcca ctggcgctgc ctctggcatc atgtcccttg    480

ctggtcttgt tttggcacca tttacagcag ggacgagtct ggcccttact gcagctgggg    540

tagggctggg agcagcgtct gctgtgactg ggatcaccac cagcatcgtg gagcactcat    600

acacatcatc agcagaagct gaagccagca ggctgactgc aaccagcatt gaccgattga    660

aggtatttaa ggaagttatg cgtgacatca cacccaactt actttccctt cttaataatt    720

attacgaagc cacacaaacc attgggagtg aaatccgtgc catcaggcaa gccagagcca    780

gggcccgact ccctgtgacc acctggcgaa tctcagctgg aagtggtggt caagcagaga    840

gaacgattgc aggcaccacc cgggcagtga gcagaggagc ccggatcctg agtgcgacca    900

cttcaggcat cttccttgca ctggatgtgg tcaaccttgt atacgagtca aagcacttgc    960

atgagggggc aaagtctgca tctgctgagg agctgaggcg gcaggctcag gagctggagg   1020

agaatctaat ggagctcact cagatctatc agcgtctgaa tccatgccat acccactgac   1080

cccagaccag tgcagccagc aggggaggtg agccatacac aggccacgac aaaatgcagg   1140

cattttatta gggggataaa gagggcaagg taaagtttat ggagctgagt gttagtgact   1200

ttggcatttc tgtagctgag cacagcaggg gaggggttaa tgcagatggc aagtgcacca   1260

aggagaaggc aggaatgctg gagcctggaa taagggagga gaggggactg gagagtgtgg   1320

ggaataggaa gaagaaattt cctttagact aacgaatata ttggggggag gaatagaggg   1380

gaggtgtgca ggaaccagca atgagaaggc caggaaaaga aagagctgaa aatgcagaaa   1440

gccgaagagt tagaactttt ggatacagca gaagaaacag cggctccact accgacctgc   1500

ccccggttcg atgtccttcc aagaatgaag tctttccctg gtgatggtcc cctgccctgt   1560

ctttccagca tccactctgt cttgtcctcc tggaagtgta tctcagtcag ccagtggctt   1620

cttgatgatg gcggtggagg tggtggttgt agtgtgatgg atccccttta ggttatttag   1680

gggtatatgt cccctgcttg aaccctgaag gccaggtaat gagccatggc cattgtcccc   1740

agctgaggac caggtgtctc taaaaaccca aacatcctgg agagtatgcg agaacctacc   1800

aagaaaaaca gtctcattac tcatatacag caggcaaaga gacagaaaat taactgaaaa   1860

gcagtttaga gactggggga ggccggatct ctagagccat cctgctgagt gccctgtgtg   1920

taagtcctaa taaactcacc tactcaccaa g                                  1951


<210>  10438
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10438

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10439
<211>  2104
<212>  DNA
<213>  Homo sapiens

<400>  10439
gaagctgggc catgttgtcc agaggctggt tgcttttagt ccaagtgctg cctcccacac     60

ctcggatttc agccaggctg tgccacggag ggcagaggcc acccaggtgg ctcacattca    120

gtcccacaat ttgctttctc ctcctcaagg gttaagaaaa aaaacgaacc cttccagtca    180

ggtcagtgac tggagagctc catggaaagt ctctcagtga cctggctgct ggcaccatgg    240

actcagaaaa gaaacgcttt actgaagagg ccaccaaata cttccgggag agagtcagcc    300

cagtgcatct gcaaatcctg ctgactaaca atgaagcctg gaagagattc gtgactgcgg    360

ctgaattgcc cagggatgag gcagatgctc tctacgaagc tctgaagaag cttagaacat    420

atgcagctat tgaggacgaa tatgtgcagc agaaagatga gcagtttagg gaatggtttt    480

tgaaagagtt tccccaagtc aagaggaaga tccaggagtc catagaaaag cttcgtgccc    540

ttgcaaatgg tattgaagag gtccacagag gctgcaccat ctccaatgtg gtgtccagct    600

ccactggcgc tgcctctggc atcatgtccc ttgctggtct tgttttggca ccatttacag    660

cagggacgag tctggccctt actgcagctg gggtagggct gggagcagcg tctgctgtga    720

ctgggatcac caccagcatc gtggagcact catacacatc atcagcagaa gctgaagcca    780

gcaggctgac tgcaaccagc attgaccgat tgaaggtatt taaggaagtt atgcgtgaca    840

tcacacccaa cttactttcc cttcttaata attattacga agccacacaa accattggga    900

gtgaaatccg tgccatcagg caagccagag ccagggcccg actccctgtg accacctggc    960

gaatctcagc tggaagtggt ggtcaagcag agagaacgat tgcaggcacc acccgggcag   1020

tgagcagagg agcccggatc ctgagtgcga ccacttcagg catcttcctt gcactggatg   1080

tggtcaacct tgtatacgag tcaaagcact tgcatgaggg ggcaaagtct gcatctgctg   1140

aggagctgag gcggcaggct caggagctgg aggagaatct aatggagctc actcagatct   1200

atcagcgtct gaatccatgc catacccact gaccccagac cagtgcagcc agcaggggag   1260

gtgagccata cacaggccac gacaaaatgc aggcatttta ttagggggat aaagagggca   1320

aggtaaagtt tatggagctg agtgttagtg actttggcat ttctgtagct gagcacagca   1380

ggggaggggt taatgcagat ggcaagtgca ccaaggagaa ggcaggaatg ctggagcctg   1440

gaataaggga ggagagggga ctggagagtg tggggaatag gaagaagaaa tttcctttag   1500

actaacgaat atattggggg gaggaataga ggggaggtgt gcaggaacca gcaatgagaa   1560

ggccaggaaa agaaagagct gaaaatgcag aaagccgaag agttagaact tttggataca   1620

gcagaagaaa cagcggctcc actaccgacc tgcccccggt tcgatgtcct tccaagaatg   1680

aagtctttcc ctggtgatgg tcccctgccc tgtctttcca gcatccactc tgtcttgtcc   1740

tcctggaagt gtatctcagt cagccagtgg cttcttgatg atggcggtgg aggtggtggt   1800

tgtagtgtga tggatcccct ttaggttatt taggggtata tgtcccctgc ttgaaccctg   1860

aaggccaggt aatgagccat ggccattgtc cccagctgag gaccaggtgt ctctaaaaac   1920

ccaaacatcc tggagagtat gcgagaacct accaagaaaa acagtctcat tactcatata   1980

cagcaggcaa agagacagaa aattaactga aaagcagttt agagactggg ggaggccgga   2040

tctctagagc catcctgctg agtgccctgt gtgtaagtcc taataaactc acctactcac   2100

caag                                                                2104


<210>  10440
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10440

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10441
<211>  2067
<212>  DNA
<213>  Homo sapiens

<400>  10441
gaaactgaag ctgggccatg ttgtccagag gctggttgct tttagtccaa gtgctgcctc     60

ccacacctcg gatttcagcc aggctgtgcc acggagggca gaggccaccc agggttaaga    120

aaaaaaacga acccttccag tcaggtcagt gactggagag ctccatggaa agtctctcag    180

tgacctggct gctggcacca tggactcaga aaagaaacgc tttactgaag aggccaccaa    240

atacttccgg gagagagtca gcccagtgca tctgcaaatc ctgctgacta acaatgaagc    300

ctggaagaga ttcgtgactg cggctgaatt gcccagggat gaggcagatg ctctctacga    360

agctctgaag aagcttagaa catatgcagc tattgaggac gaatatgtgc agcagaaaga    420

tgagcagttt agggaatggt ttttgaaaga gtttccccaa gtcaagagga agatccagga    480

gtccatagaa aagcttcgtg cccttgcaaa tggtattgaa gaggtccaca gaggctgcac    540

catctccaat gtggtgtcca gctccactgg cgctgcctct ggcatcatgt cccttgctgg    600

tcttgttttg gcaccattta cagcagggac gagtctggcc cttactgcag ctggggtagg    660

gctgggagca gcgtctgctg tgactgggat caccaccagc atcgtggagc actcatacac    720

atcatcagca gaagctgaag ccagcaggct gactgcaacc agcattgacc gattgaaggt    780

atttaaggaa gttatgcgtg acatcacacc caacttactt tcccttctta ataattatta    840

cgaagccaca caaaccattg ggagtgaaat ccgtgccatc aggcaagcca gagccagggc    900

ccgactccct gtgaccacct ggcgaatctc agctggaagt ggtggtcaag cagagagaac    960

gattgcaggc accacccggg cagtgagcag aggagcccgg atcctgagtg cgaccacttc   1020

aggcatcttc cttgcactgg atgtggtcaa ccttgtatac gagtcaaagc acttgcatga   1080

gggggcaaag tctgcatctg ctgaggagct gaggcggcag gctcaggagc tggaggagaa   1140

tctaatggag ctcactcaga tctatcagcg tctgaatcca tgccataccc actgacccca   1200

gaccagtgca gccagcaggg gaggtgagcc atacacaggc cacgacaaaa tgcaggcatt   1260

ttattagggg gataaagagg gcaaggtaaa gtttatggag ctgagtgtta gtgactttgg   1320

catttctgta gctgagcaca gcaggggagg ggttaatgca gatggcaagt gcaccaagga   1380

gaaggcagga atgctggagc ctggaataag ggaggagagg ggactggaga gtgtggggaa   1440

taggaagaag aaatttcctt tagactaacg aatatattgg ggggaggaat agaggggagg   1500

tgtgcaggaa ccagcaatga gaaggccagg aaaagaaaga gctgaaaatg cagaaagccg   1560

aagagttaga acttttggat acagcagaag aaacagcggc tccactaccg acctgccccc   1620

ggttcgatgt ccttccaaga atgaagtctt tccctggtga tggtcccctg ccctgtcttt   1680

ccagcatcca ctctgtcttg tcctcctgga agtgtatctc agtcagccag tggcttcttg   1740

atgatggcgg tggaggtggt ggttgtagtg tgatggatcc cctttaggtt atttaggggt   1800

atatgtcccc tgcttgaacc ctgaaggcca ggtaatgagc catggccatt gtccccagct   1860

gaggaccagg tgtctctaaa aacccaaaca tcctggagag tatgcgagaa cctaccaaga   1920

aaaacagtct cattactcat atacagcagg caaagagaca gaaaattaac tgaaaagcag   1980

tttagagact gggggaggcc ggatctctag agccatcctg ctgagtgccc tgtgtgtaag   2040

tcctaataaa ctcacctact caccaag                                       2067


<210>  10442
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10442

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10443
<211>  1964
<212>  DNA
<213>  Homo sapiens

<400>  10443
ttatgcagat gcacggctgg aggtgggatc cacacagctc agaacagctg gatcttgctc     60

acactctttc aagagaagct tccttgggtt aagaaaaaaa acgaaccctt ccagtcaggt    120

cagtgactgg agagctccat ggaaagtctc tcagtgacct ggctgctggc accatggact    180

cagaaaagaa acgctttact gaagagattc gtgactgcgg ctgaattgcc cagggatgag    240

gcagatgctc tctacgaagc tctgaagaag cttagaacat atgcagctat tgaggacgaa    300

tatgtgcagc agaaagatga gcagtttagg gaatggtttt tgaaagagtt tccccaagtc    360

aagaggaaga tccaggagtc catagaaaag cttcgtgccc ttgcaaatgg tattgaagag    420

gtccacagag gctgcaccat ctccaatgtg gtgtccagct ccactggcgc tgcctctggc    480

atcatgtccc ttgctggtct tgttttggca ccatttacag cagggacgag tctggccctt    540

actgcagctg gggtagggct gggagcagcg tctgctgtga ctgggatcac caccagcatc    600

gtggagcact catacacatc atcagcagaa gctgaagcca gcaggctgac tgcaaccagc    660

attgaccgat tgaaggtatt taaggaagtt atgcgtgaca tcacacccaa cttactttcc    720

cttcttaata attattacga agccacacaa accattggga gtgaaatccg tgccatcagg    780

caagccagag ccagggcccg actccctgtg accacctggc gaatctcagc tggaagtggt    840

ggtcaagcag agagaacgat tgcaggcacc acccgggcag tgagcagagg agcccggatc    900

ctgagtgcga ccacttcagg catcttcctt gcactggatg tggtcaacct tgtatacgag    960

tcaaagcact tgcatgaggg ggcaaagtct gcatctgctg aggagctgag gcggcaggct   1020

caggagctgg aggagaatct aatggagctc actcagatct atcagcgtct gaatccatgc   1080

catacccact gaccccagac cagtgcagcc agcaggggag gtgagccata cacaggccac   1140

gacaaaatgc aggcatttta ttagggggat aaagagggca aggtaaagtt tatggagctg   1200

agtgttagtg actttggcat ttctgtagct gagcacagca ggggaggggt taatgcagat   1260

ggcaagtgca ccaaggagaa ggcaggaatg ctggagcctg gaataaggga ggagagggga   1320

ctggagagtg tggggaatag gaagaagaaa tttcctttag actaacgaat atattggggg   1380

gaggaataga ggggaggtgt gcaggaacca gcaatgagaa ggccaggaaa agaaagagct   1440

gaaaatgcag aaagccgaag agttagaact tttggataca gcagaagaaa cagcggctcc   1500

actaccgacc tgcccccggt tcgatgtcct tccaagaatg aagtctttcc ctggtgatgg   1560

tcccctgccc tgtctttcca gcatccactc tgtcttgtcc tcctggaagt gtatctcagt   1620

cagccagtgg cttcttgatg atggcggtgg aggtggtggt tgtagtgtga tggatcccct   1680

ttaggttatt taggggtata tgtcccctgc ttgaaccctg aaggccaggt aatgagccat   1740

ggccattgtc cccagctgag gaccaggtgt ctctaaaaac ccaaacatcc tggagagtat   1800

gcgagaacct accaagaaaa acagtctcat tactcatata cagcaggcaa agagacagaa   1860

aattaactga aaagcagttt agagactggg ggaggccgga tctctagagc catcctgctg   1920

agtgccctgt gtgtaagtcc taataaactc acctactcac caag                    1964


<210>  10444
<211>  317
<212>  PRT
<213>  Homo sapiens

<400>  10444

Met Glu Ser Leu Ser Val Thr Trp Leu Leu Ala Pro Trp Thr Gln Lys 
1               5                   10                  15


Arg Asn Ala Leu Leu Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg 
            20                  25                  30


Asp Glu Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr 
        35                  40                  45


Ala Ala Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg 
    50                  55                  60


Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu 
65                  70                  75                  80


Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His 
                85                  90                  95


Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala 
            100                 105                 110


Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala 
        115                 120                 125


Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala 
    130                 135                 140


Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr 
145                 150                 155                 160


Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp 
                165                 170                 175


Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu 
            180                 185                 190


Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser 
        195                 200                 205


Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val 
    210                 215                 220


Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr 
225                 230                 235                 240


Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser 
                245                 250                 255


Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val 
            260                 265                 270


Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu 
        275                 280                 285


Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu 
    290                 295                 300


Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
305                 310                 315


<210>  10445
<211>  2085
<212>  DNA
<213>  Homo sapiens

<400>  10445
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggtg gctcacattc agtcccacaa tttgctttct    120

cctcctcaag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    180

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    240

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    300

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    360

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    420

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    480

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    540

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    600

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct    660

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    720

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    780

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    840

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag    900

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg    960

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1020

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1080

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1140

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1200

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1260

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1320

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1380

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1440

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1500

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1560

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1620

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1680

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1740

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1800

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1860

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   1920

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   1980

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2040

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaag                   2085


<210>  10446
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10446

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10447
<211>  2205
<212>  DNA
<213>  Homo sapiens

<400>  10447
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttgaga tgagcatcta gatagcaagg aaaaacattc    120

aatccctcaa ctgaaagtga aactgaagct gggccatgtt gtccagaggc tggttgcttt    180

tagtccaagt gctgcctccc acacctcgga tttcagccag gctgtgccac ggagggcaga    240

ggccacccag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    300

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    360

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    420

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    480

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    540

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    600

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    660

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    720

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct    780

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    840

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    900

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    960

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag   1020

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg   1080

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1140

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1200

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1260

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1320

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1380

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1440

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1500

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1560

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1620

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1680

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1740

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1800

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1860

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1920

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1980

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   2040

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   2100

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2160

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaag                   2205


<210>  10448
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10448

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10449
<211>  1858
<212>  DNA
<213>  Homo sapiens

<400>  10449
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttgaaa agaaacgctt tactgaagag gccaccaaat    120

acttcaggga tgaggcagat gctctctacg aagctctgaa gaagcttaga acatatgcag    180

ctattgagga cgaatatgtg cagcagaaag atgagcagtt tagggaatgg tttttgaaag    240

agtttcccca agtcaagagg aagatccagg agtccataga aaagcttcgt gcccttgcaa    300

atggtattga agaggtccac agaggctgca ccatctccaa tgtggtgtcc agctccactg    360

gcgctgcctc tggcatcatg tcccttgctg gtcttgtttt ggcaccattt acagcaggga    420

cgagtctggc ccttactgca gctggggtag ggctgggagc agcgtctgct gtgactggga    480

tcaccaccag catcgtggag cactcataca catcatcagc agaagctgaa gccagcaggc    540

tgactgcaac cagcattgac cgattgaagg tatttaagga agttatgcgt gacatcacac    600

ccaacttact ttcccttctt aataattatt acgaagccac acaaaccatt gggagtgaaa    660

tccgtgccat caggcaagcc agagccaggg cccgactccc tgtgaccacc tggcgaatct    720

cagctggaag tggtggtcaa gcagagagaa cgattgcagg caccacccgg gcagtgagca    780

gaggagcccg gatcctgagt gcgaccactt caggcatctt ccttgcactg gatgtggtca    840

accttgtata cgagtcaaag cacttgcatg agggggcaaa gtctgcatct gctgaggagc    900

tgaggcggca ggctcaggag ctggaggaga atctaatgga gctcactcag atctatcagc    960

gtctgaatcc atgccatacc cactgacccc agaccagtgc agccagcagg ggaggtgagc   1020

catacacagg ccacgacaaa atgcaggcat tttattaggg ggataaagag ggcaaggtaa   1080

agtttatgga gctgagtgtt agtgactttg gcatttctgt agctgagcac agcaggggag   1140

gggttaatgc agatggcaag tgcaccaagg agaaggcagg aatgctggag cctggaataa   1200

gggaggagag gggactggag agtgtgggga ataggaagaa gaaatttcct ttagactaac   1260

gaatatattg gggggaggaa tagaggggag gtgtgcagga accagcaatg agaaggccag   1320

gaaaagaaag agctgaaaat gcagaaagcc gaagagttag aacttttgga tacagcagaa   1380

gaaacagcgg ctccactacc gacctgcccc cggttcgatg tccttccaag aatgaagtct   1440

ttccctggtg atggtcccct gccctgtctt tccagcatcc actctgtctt gtcctcctgg   1500

aagtgtatct cagtcagcca gtggcttctt gatgatggcg gtggaggtgg tggttgtagt   1560

gtgatggatc ccctttaggt tatttagggg tatatgtccc ctgcttgaac cctgaaggcc   1620

aggtaatgag ccatggccat tgtccccagc tgaggaccag gtgtctctaa aaacccaaac   1680

atcctggaga gtatgcgaga acctaccaag aaaaacagtc tcattactca tatacagcag   1740

gcaaagagac agaaaattaa ctgaaaagca gtttagagac tgggggaggc cggatctcta   1800

gagccatcct gctgagtgcc ctgtgtgtaa gtcctaataa actcacctac tcaccaag     1858


<210>  10450
<211>  51
<212>  PRT
<213>  Homo sapiens

<400>  10450

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Lys Arg Asn Ala 
            20                  25                  30


Leu Leu Lys Arg Pro Pro Asn Thr Ser Gly Met Arg Gln Met Leu Ser 
        35                  40                  45


Thr Lys Leu 
    50


<210>  10451
<211>  2065
<212>  DNA
<213>  Homo sapiens

<400>  10451
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggac aaaaggaccc tgccttggtg tgagagtgag    120

ggcagaggga gctggagcaa gtagaatttc tctaaatacc agctggctgg ggcccaggag    180

attaaaaaac accgggctag gttggtcttg gcatttgctg acacgcaaag ggattgcaga    240

gatccagccc ctccaacctc cctctgtcca caggtggctc acattcagtc ccacaatttg    300

ctttctcctc ctcaagggtt aagaaaaaaa acgaaccctt ccagtcaggt cagtgactgg    360

agagctccat ggaaagtctc tcagtgacct ggctgctggc accatggact cagaaagatg    420

agcagtttag ggaatggttt ttgaaagagt ttccccaagt caagaggaag atccaggagt    480

ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga ggtccacaga ggctgcacca    540

tctccaatgt ggtgtccagc tccactggcg ctgcctctgg catcatgtcc cttgctggtc    600

ttgttttggc accatttaca gcagggacga gtctggccct tactgcagct ggggtagggc    660

tgggagcagc gtctgctgtg actgggatca ccaccagcat cgtggagcac tcatacacat    720

catcagcaga agctgaagcc agcaggctga ctgcaaccag cattgaccga ttgaaggtat    780

ttaaggaagt tatgcgtgac atcacaccca acttactttc ccttcttaat aattattacg    840

aagccacaca aaccattggg agtgaaatcc gtgccatcag gcaagccaga gccagggccc    900

gactccctgt gaccacctgg cgaatctcag ctggaagtgg tggtcaagca gagagaacga    960

ttgcaggcac cacccgggca gtgagcagag gagcccggat cctgagtgcg accacttcag   1020

gcatcttcct tgcactggat gtggtcaacc ttgtatacga gtcaaagcac ttgcatgagg   1080

gggcaaagtc tgcatctgct gaggagctga ggcggcaggc tcaggagctg gaggagaatc   1140

taatggagct cactcagatc tatcagcgtc tgaatccatg ccatacccac tgaccccaga   1200

ccagtgcagc cagcagggga ggtgagccat acacaggcca cgacaaaatg caggcatttt   1260

attaggggga taaagagggc aaggtaaagt ttatggagct gagtgttagt gactttggca   1320

tttctgtagc tgagcacagc aggggagggg ttaatgcaga tggcaagtgc accaaggaga   1380

aggcaggaat gctggagcct ggaataaggg aggagagggg actggagagt gtggggaata   1440

ggaagaagaa atttccttta gactaacgaa tatattgggg ggaggaatag aggggaggtg   1500

tgcaggaacc agcaatgaga aggccaggaa aagaaagagc tgaaaatgca gaaagccgaa   1560

gagttagaac ttttggatac agcagaagaa acagcggctc cactaccgac ctgcccccgg   1620

ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg gtcccctgcc ctgtctttcc   1680

agcatccact ctgtcttgtc ctcctggaag tgtatctcag tcagccagtg gcttcttgat   1740

gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc tttaggttat ttaggggtat   1800

atgtcccctg cttgaaccct gaaggccagg taatgagcca tggccattgt ccccagctga   1860

ggaccaggtg tctctaaaaa cccaaacatc ctggagagta tgcgagaacc taccaagaaa   1920

aacagtctca ttactcatat acagcaggca aagagacaga aaattaactg aaaagcagtt   1980

tagagactgg gggaggccgg atctctagag ccatcctgct gagtgccctg tgtgtaagtc   2040

ctaataaact cacctactca ccaag                                         2065


<210>  10452
<211>  274
<212>  PRT
<213>  Homo sapiens

<400>  10452

Met Glu Ser Leu Ser Val Thr Trp Leu Leu Ala Pro Trp Thr Gln Lys 
1               5                   10                  15


Asp Glu Gln Phe Arg Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys 
            20                  25                  30


Arg Lys Ile Gln Glu Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly 
        35                  40                  45


Ile Glu Glu Val His Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser 
    50                  55                  60


Ser Thr Gly Ala Ala Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu 
65                  70                  75                  80


Ala Pro Phe Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val 
                85                  90                  95


Gly Leu Gly Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val 
            100                 105                 110


Glu His Ser Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr 
        115                 120                 125


Ala Thr Ser Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp 
    130                 135                 140


Ile Thr Pro Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr 
145                 150                 155                 160


Gln Thr Ile Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg 
                165                 170                 175


Ala Arg Leu Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly 
            180                 185                 190


Gln Ala Glu Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly 
        195                 200                 205


Ala Arg Ile Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp 
    210                 215                 220


Val Val Asn Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys 
225                 230                 235                 240


Ser Ala Ser Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu 
                245                 250                 255


Asn Leu Met Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His 
            260                 265                 270


Thr His 



<210>  10453
<211>  1873
<212>  DNA
<213>  Homo sapiens

<400>  10453
actttccctt ttgggttcca gggtatatct cagagcctgg agaacgtgtc tggttattat     60

gcagatgcac ggctggaggt gggatccaca cagctcagaa cagctggatc ttgctcacac    120

tctttcaaga gaagcttcct tgggatgagg cagatgctct ctacgaagct ctgaagaagc    180

ttagaacata tgcagctatt gaggacgaat atgtgcagca gaaagatgag cagtttaggg    240

aatggttttt gaaagagttt ccccaagtca agaggaagat ccaggagtcc atagaaaagc    300

ttcgtgccct tgcaaatggt attgaagagg tccacagagg ctgcaccatc tccaatgtgg    360

tgtccagctc cactggcgct gcctctggca tcatgtccct tgctggtctt gttttggcac    420

catttacagc agggacgagt ctggccctta ctgcagctgg ggtagggctg ggagcagcgt    480

ctgctgtgac tgggatcacc accagcatcg tggagcactc atacacatca tcagcagaag    540

ctgaagccag caggctgact gcaaccagca ttgaccgatt gaaggtattt aaggaagtta    600

tgcgtgacat cacacccaac ttactttccc ttcttaataa ttattacgaa gccacacaaa    660

ccattgggag tgaaatccgt gccatcaggc aagccagagc cagggcccga ctccctgtga    720

ccacctggcg aatctcagct ggaagtggtg gtcaagcaga gagaacgatt gcaggcacca    780

cccgggcagt gagcagagga gcccggatcc tgagtgcgac cacttcaggc atcttccttg    840

cactggatgt ggtcaacctt gtatacgagt caaagcactt gcatgagggg gcaaagtctg    900

catctgctga ggagctgagg cggcaggctc aggagctgga ggagaatcta atggagctca    960

ctcagatcta tcagcgtctg aatccatgcc atacccactg accccagacc agtgcagcca   1020

gcaggggagg tgagccatac acaggccacg acaaaatgca ggcattttat tagggggata   1080

aagagggcaa ggtaaagttt atggagctga gtgttagtga ctttggcatt tctgtagctg   1140

agcacagcag gggaggggtt aatgcagatg gcaagtgcac caaggagaag gcaggaatgc   1200

tggagcctgg aataagggag gagaggggac tggagagtgt ggggaatagg aagaagaaat   1260

ttcctttaga ctaacgaata tattgggggg aggaatagag gggaggtgtg caggaaccag   1320

caatgagaag gccaggaaaa gaaagagctg aaaatgcaga aagccgaaga gttagaactt   1380

ttggatacag cagaagaaac agcggctcca ctaccgacct gcccccggtt cgatgtcctt   1440

ccaagaatga agtctttccc tggtgatggt cccctgccct gtctttccag catccactct   1500

gtcttgtcct cctggaagtg tatctcagtc agccagtggc ttcttgatga tggcggtgga   1560

ggtggtggtt gtagtgtgat ggatcccctt taggttattt aggggtatat gtcccctgct   1620

tgaaccctga aggccaggta atgagccatg gccattgtcc ccagctgagg accaggtgtc   1680

tctaaaaacc caaacatcct ggagagtatg cgagaaccta ccaagaaaaa cagtctcatt   1740

actcatatac agcaggcaaa gagacagaaa attaactgaa aagcagttta gagactgggg   1800

gaggccggat ctctagagcc atcctgctga gtgccctgtg tgtaagtcct aataaactca   1860

cctactcacc aag                                                      1873


<210>  10454
<211>  202
<212>  PRT
<213>  Homo sapiens

<400>  10454

Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr Ser 
1               5                   10                  15


Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala Val 
            20                  25                  30


Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser Ala 
        35                  40                  45


Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu Lys 
    50                  55                  60


Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser Leu 
65                  70                  75                  80


Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile Arg 
                85                  90                  95


Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr Trp 
            100                 105                 110


Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala Gly 
        115                 120                 125


Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr Thr 
    130                 135                 140


Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu Ser 
145                 150                 155                 160


Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu Arg 
                165                 170                 175


Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln Ile 
            180                 185                 190


Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        195                 200


<210>  10455
<211>  1965
<212>  DNA
<213>  Homo sapiens

<400>  10455
actttcactt tcccttttgg gttccagggt atatctcaga gcctggagaa cgtgtctggt     60

tattatgcag atgcacggct ggaggtggga tccacacagc tcagaacagc tggatcttgc    120

tcacactctt tcaagagaag cttccttggg ttaagaaaaa aaacgaaccc ttccagtcag    180

gtcagtgact ggagagctcc atggaaagtc tctcagtgac ctggctgctg gcaccatgga    240

ctcagaaaag aaacgcttta ctgaagaggc caccaaatac ttccgggaga gagtcagccc    300

agtgcatctg caaatcctgc tgactaacaa tgaagcctgg aagagattcg tgactgcggc    360

tgaattgccc agggatgagg cagatgctct ctacgaagct ctgaagaagc ttagaacata    420

tgcagctatt gaggacgaat atgtgcagca gaaagatgag cagtttaggg aatggttttt    480

gaaagagttt ccccaagtca agaggaagat ccaggagtcc atagaaaagc ttcgtgccct    540

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat    600

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag    660

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc    720

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag    780

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg    840

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat    900

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga    960

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1020

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1080

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1140

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1200

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1260

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1320

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1380

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1440

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1500

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   1560

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   1620

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   1680

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   1740

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   1800

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   1860

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   1920

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaag                   1965


<210>  10456
<211>  285
<212>  PRT
<213>  Homo sapiens

<400>  10456

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala 
            100                 105                 110


Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr 
        115                 120                 125


Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp 
    130                 135                 140


Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu 
145                 150                 155                 160


Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser 
                165                 170                 175


Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val 
            180                 185                 190


Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr 
        195                 200                 205


Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser 
    210                 215                 220


Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val 
225                 230                 235                 240


Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu 
                245                 250                 255


Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu 
            260                 265                 270


Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
        275                 280                 285


<210>  10457
<211>  2018
<212>  DNA
<213>  Homo sapiens

<400>  10457
gtgactttca ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct     60

ggttattatg cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct    120

tgctcacact ctttcaagag aagcttcctt gggttaagaa aaaaaacgaa cccttccagt    180

caggtcagtg actggagagc tccatggaaa gtctctcagt gacctggctg ctggcaccat    240

ggactcagaa aagaaacgct ttactgaaga ggccaccaaa tacttccggg agagagtcag    300

cccagtgcat ctgcaaatcc tgctgactaa caatgaagcc tggaagagat tcgtgactgc    360

ggctgaattg cccagggatg aggcagatgc tctctacgaa gctctgaaga agcttagaac    420

atatgcagct attgaggacg aatatgtgca gcagaaagat gagcagttta gggaatggtt    480

tttgaaagag tttccccaag tcaagaggaa gatccaggag tccatagaaa agcttccatg    540

tcccttgctg gtcttgtttt ggcaccattt acagcaggga cgagtctggc ccttactgca    600

gctggggtag ggctgggagc agcgtctgct gtgactggga tcaccaccag catcgtggag    660

cactcataca catcatcagc agaagctgaa gccagcaggc tgactgcaac cagcattgac    720

cgattgaagg tatttaagga agttatgcgt gacatcacac ccaacttact ttcccttctt    780

aataattatt acgaagccac acaaaccatt gggagtgaaa tccgtgccat caggcaagcc    840

agagccaggg cccgactccc tgtgaccacc tggcgaatct cagctggaag tggtggtcaa    900

gcagagagaa cgattgcagg caccacccgg gcagtgagca gaggagcccg gatcctgagt    960

gcgaccactt caggcatctt ccttgcactg gatgtggtca accttgtata cgagtcaaag   1020

cacttgcatg agggggcaaa gtctgcatct gctgaggagc tgaggcggca ggctcaggag   1080

ctggaggaga atctaatgga gctcactcag atctatcagc gtctgaatcc atgccatacc   1140

cactgacccc agaccagtgc agccagcagg ggaggtgagc catacacagg ccacgacaaa   1200

atgcaggcat tttattaggg ggataaagag ggcaaggtaa agtttatgga gctgagtgtt   1260

agtgactttg gcatttctgt agctgagcac agcaggggag gggttaatgc agatggcaag   1320

tgcaccaagg agaaggcagg aatgctggag cctggaataa gggaggagag gggactggag   1380

agtgtgggga ataggaagaa gaaatttcct ttagactaac gaatatattg gggggaggaa   1440

tagaggggag gtgtgcagga accagcaatg agaaggccag gaaaagaaag agctgaaaat   1500

gcagaaagcc gaagagttag aacttttgga tacagcagaa gaaacagcgg ctccactacc   1560

gacctgcccc cggttcgatg tccttccaag aatgaagtct ttccctggtg atggtcccct   1620

gccctgtctt tccagcatcc actctgtctt gtcctcctgg aagtgtatct cagtcagcca   1680

gtggcttctt gatgatggcg gtggaggtgg tggttgtagt gtgatggatc ccctttaggt   1740

tatttagggg tatatgtccc ctgcttgaac cctgaaggcc aggtaatgag ccatggccat   1800

tgtccccagc tgaggaccag gtgtctctaa aaacccaaac atcctggaga gtatgcgaga   1860

acctaccaag aaaaacagtc tcattactca tatacagcag gcaaagagac agaaaattaa   1920

ctgaaaagca gtttagagac tgggggaggc cggatctcta gagccatcct gctgagtgcc   1980

ctgtgtgtaa gtcctaataa actcacctac tcaccaag                           2018


<210>  10458
<211>  223
<212>  PRT
<213>  Homo sapiens

<400>  10458

Met Val Phe Glu Arg Val Ser Pro Ser Gln Glu Glu Asp Pro Gly Val 
1               5                   10                  15


His Arg Lys Ala Ser Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe 
            20                  25                  30


Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly 
        35                  40                  45


Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser 
    50                  55                  60


Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser 
65                  70                  75                  80


Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro 
                85                  90                  95


Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile 
            100                 105                 110


Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu 
        115                 120                 125


Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu 
    130                 135                 140


Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile 
145                 150                 155                 160


Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn 
                165                 170                 175


Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser 
            180                 185                 190


Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met 
        195                 200                 205


Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
    210                 215                 220


<210>  10459
<211>  2329
<212>  DNA
<213>  Homo sapiens

<400>  10459
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt ggacaaaagg accctgcctt ggtgtgagag tgagggcaga    300

gggagctgga gcaagtagaa tttctctaaa taccagctgg ctggggccca ggagattaaa    360

aaacaccggg ctagggttaa gaaaaaaaac gaacccttcc agtcaggtca gtgactggag    420

agctccatgg aaagtctctc agtgacctgg ctgctggcac catggactca gaaaagaaac    480

gctttactga agaggccacc aaatacttcc gggagagagt cagcccagtg catctgcaaa    540

tcctgctgac taacaatgaa gcctggaaga gattcgtgac tgcggctgaa ttgcccaggg    600

atgaggcaga tgctctctac gaagctctga agaagcttag aacatatgca gctattgagg    660

acgaatatgt gcagcagaaa gatgagcagt ttagggaatg gtttttgaaa gagtttcccc    720

aagtcaagag gaagatccag gagtccatag aaaagcttcg tgcccttgca aatggtattg    780

aagaggtcca cagaggctgc accatctcca atgtggtgtc cagctccact ggcgctgcct    840

ctggcatcat gtcccttgct ggtcttgttt tggcaccatt tacagcaggg acgagtctgg    900

cccttactgc agctggggta gggctgggag cagcgtctgc tgtgactggg atcaccacca    960

gcatcgtgga gcactcatac acatcatcag cagaagctga agccagcagg ctgactgcaa   1020

ccagcattga ccgattgaag gtatttaagg aagttatgcg tgacatcaca cccaacttac   1080

tttcccttct taataattat tacgaagcca cacaaaccat tgggagtgaa atccgtgcca   1140

tcaggcaagc cagagccagg gcccgactcc ctgtgaccac ctggcgaatc tcagctggaa   1200

gtggtggtca agcagagaga acgattgcag gcaccacccg ggcagtgagc agaggagccc   1260

ggatcctgag tgcgaccact tcaggcatct tccttgcact ggatgtggtc aaccttgtat   1320

acgagtcaaa gcacttgcat gagggggcaa agtctgcatc tgctgaggag ctgaggcggc   1380

aggctcagga gctggaggag aatctaatgg agctcactca gatctatcag cgtctgaatc   1440

catgccatac ccactgaccc cagaccagtg cagccagcag gggaggtgag ccatacacag   1500

gccacgacaa aatgcaggca ttttattagg gggataaaga gggcaaggta aagtttatgg   1560

agctgagtgt tagtgacttt ggcatttctg tagctgagca cagcagggga ggggttaatg   1620

cagatggcaa gtgcaccaag gagaaggcag gaatgctgga gcctggaata agggaggaga   1680

ggggactgga gagtgtgggg aataggaaga agaaatttcc tttagactaa cgaatatatt   1740

ggggggagga atagagggga ggtgtgcagg aaccagcaat gagaaggcca ggaaaagaaa   1800

gagctgaaaa tgcagaaagc cgaagagtta gaacttttgg atacagcaga agaaacagcg   1860

gctccactac cgacctgccc ccggttcgat gtccttccaa gaatgaagtc tttccctggt   1920

gatggtcccc tgccctgtct ttccagcatc cactctgtct tgtcctcctg gaagtgtatc   1980

tcagtcagcc agtggcttct tgatgatggc ggtggaggtg gtggttgtag tgtgatggat   2040

cccctttagg ttatttaggg gtatatgtcc cctgcttgaa ccctgaaggc caggtaatga   2100

gccatggcca ttgtccccag ctgaggacca ggtgtctcta aaaacccaaa catcctggag   2160

agtatgcgag aacctaccaa gaaaaacagt ctcattactc atatacagca ggcaaagaga   2220

cagaaaatta actgaaaagc agtttagaga ctgggggagg ccggatctct agagccatcc   2280

tgctgagtgc cctgtgtgta agtcctaata aactcaccta ctcaccaag               2329


<210>  10460
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10460

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10461
<211>  2445
<212>  DNA
<213>  Homo sapiens

<400>  10461
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt ggacaaaagg accctgcctt ggtgtgagag tgagggcaga    300

gggagctgga gcaagtagaa tttctctaaa taccagctgg ctggggccca ggagattaaa    360

aaacaccggg ctaggttggt cttggcattt gctgacacgc aaagggattg cagagatcca    420

gcccctccaa cctccctctg tccacaggtg gctcacattc agtcccacaa tttgctttct    480

cctcctcaag ggttaagaaa aaaaacgaac ccttccagtc aggtcagtga ctggagagct    540

ccatggaaag tctctcagtg acctggctgc tggcaccatg gactcagaaa agaaacgctt    600

tactgaagag gccaccaaat acttccggga gagagtcagc ccagtgcatc tgcaaatcct    660

gctgactaac aatgaagcct ggaagagatt cgtgactgcg gctgaattgc ccagggatga    720

ggcagatgct ctctacgaag ctctgaagaa gcttagaaca tatgcagcta ttgaggacga    780

atatgtgcag cagaaagatg agcagtttag ggaatggttt ttgaaagagt ttccccaagt    840

caagaggaag atccaggagt ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga    900

ggtccacaga ggctgcacca tctccaatgt ggtgtccagc tccactggcg ctgcctctgg    960

catcatgtcc cttgctggtc ttgttttggc accatttaca gcagggacga gtctggccct   1020

tactgcagct ggggtagggc tgggagcagc gtctgctgtg actgggatca ccaccagcat   1080

cgtggagcac tcatacacat catcagcaga agctgaagcc agcaggctga ctgcaaccag   1140

cattgaccga ttgaaggtat ttaaggaagt tatgcgtgac atcacaccca acttactttc   1200

ccttcttaat aattattacg aagccacaca aaccattggg agtgaaatcc gtgccatcag   1260

gcaagccaga gccagggccc gactccctgt gaccacctgg cgaatctcag ctggaagtgg   1320

tggtcaagca gagagaacga ttgcaggcac cacccgggca gtgagcagag gagcccggat   1380

cctgagtgcg accacttcag gcatcttcct tgcactggat gtggtcaacc ttgtatacga   1440

gtcaaagcac ttgcatgagg gggcaaagtc tgcatctgct gaggagctga ggcggcaggc   1500

tcaggagctg gaggagaatc taatggagct cactcagatc tatcagcgtc tgaatccatg   1560

ccatacccac tgaccccaga ccagtgcagc cagcagggga ggtgagccat acacaggcca   1620

cgacaaaatg caggcatttt attaggggga taaagagggc aaggtaaagt ttatggagct   1680

gagtgttagt gactttggca tttctgtagc tgagcacagc aggggagggg ttaatgcaga   1740

tggcaagtgc accaaggaga aggcaggaat gctggagcct ggaataaggg aggagagggg   1800

actggagagt gtggggaata ggaagaagaa atttccttta gactaacgaa tatattgggg   1860

ggaggaatag aggggaggtg tgcaggaacc agcaatgaga aggccaggaa aagaaagagc   1920

tgaaaatgca gaaagccgaa gagttagaac ttttggatac agcagaagaa acagcggctc   1980

cactaccgac ctgcccccgg ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg   2040

gtcccctgcc ctgtctttcc agcatccact ctgtcttgtc ctcctggaag tgtatctcag   2100

tcagccagtg gcttcttgat gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc   2160

tttaggttat ttaggggtat atgtcccctg cttgaaccct gaaggccagg taatgagcca   2220

tggccattgt ccccagctga ggaccaggtg tctctaaaaa cccaaacatc ctggagagta   2280

tgcgagaacc taccaagaaa aacagtctca ttactcatat acagcaggca aagagacaga   2340

aaattaactg aaaagcagtt tagagactgg gggaggccgg atctctagag ccatcctgct   2400

gagtgccctg tgtgtaagtc ctaataaact cacctactca ccaag                   2445


<210>  10462
<211>  331
<212>  PRT
<213>  Homo sapiens

<400>  10462

Met Asp Ser Glu Lys Lys Arg Phe Thr Glu Glu Ala Thr Lys Tyr Phe 
1               5                   10                  15


Arg Glu Arg Val Ser Pro Val His Leu Gln Ile Leu Leu Thr Asn Asn 
            20                  25                  30


Glu Ala Trp Lys Arg Phe Val Thr Ala Ala Glu Leu Pro Arg Asp Glu 
        35                  40                  45


Ala Asp Ala Leu Tyr Glu Ala Leu Lys Lys Leu Arg Thr Tyr Ala Ala 
    50                  55                  60


Ile Glu Asp Glu Tyr Val Gln Gln Lys Asp Glu Gln Phe Arg Glu Trp 
65                  70                  75                  80


Phe Leu Lys Glu Phe Pro Gln Val Lys Arg Lys Ile Gln Glu Ser Ile 
                85                  90                  95


Glu Lys Leu Arg Ala Leu Ala Asn Gly Ile Glu Glu Val His Arg Gly 
            100                 105                 110


Cys Thr Ile Ser Asn Val Val Ser Ser Ser Thr Gly Ala Ala Ser Gly 
        115                 120                 125


Ile Met Ser Leu Ala Gly Leu Val Leu Ala Pro Phe Thr Ala Gly Thr 
    130                 135                 140


Ser Leu Ala Leu Thr Ala Ala Gly Val Gly Leu Gly Ala Ala Ser Ala 
145                 150                 155                 160


Val Thr Gly Ile Thr Thr Ser Ile Val Glu His Ser Tyr Thr Ser Ser 
                165                 170                 175


Ala Glu Ala Glu Ala Ser Arg Leu Thr Ala Thr Ser Ile Asp Arg Leu 
            180                 185                 190


Lys Val Phe Lys Glu Val Met Arg Asp Ile Thr Pro Asn Leu Leu Ser 
        195                 200                 205


Leu Leu Asn Asn Tyr Tyr Glu Ala Thr Gln Thr Ile Gly Ser Glu Ile 
    210                 215                 220


Arg Ala Ile Arg Gln Ala Arg Ala Arg Ala Arg Leu Pro Val Thr Thr 
225                 230                 235                 240


Trp Arg Ile Ser Ala Gly Ser Gly Gly Gln Ala Glu Arg Thr Ile Ala 
                245                 250                 255


Gly Thr Thr Arg Ala Val Ser Arg Gly Ala Arg Ile Leu Ser Ala Thr 
            260                 265                 270


Thr Ser Gly Ile Phe Leu Ala Leu Asp Val Val Asn Leu Val Tyr Glu 
        275                 280                 285


Ser Lys His Leu His Glu Gly Ala Lys Ser Ala Ser Ala Glu Glu Leu 
    290                 295                 300


Arg Arg Gln Ala Gln Glu Leu Glu Glu Asn Leu Met Glu Leu Thr Gln 
305                 310                 315                 320


Ile Tyr Gln Arg Leu Asn Pro Cys His Thr His 
                325                 330


<210>  10463
<211>  2119
<212>  DNA
<213>  Homo sapiens

<400>  10463
agcaggaggg tgggaccaag ggtgctgctg gaccaaggat gggactgggc caagggtggg     60

gctgggaagc atcctgtttt gcatgtttga tcaggagctg ctgccaagtt gtgactttca    120

ctttcccttt tgggttccag ggtatatctc agagcctgga gaacgtgtct ggttattatg    180

cagatgcacg gctggaggtg ggatccacac agctcagaac agctggatct tgctcacact    240

ctttcaagag aagcttcctt gaaaagaaac gctttactga agaggccacc aaatacttcc    300

gggagagagt cagcccagtg catctgcaaa tcctgctgac taacaatgaa gcctggaaga    360

gattcgtgac tgcggctgaa ttgcccaggg atgaggcaga tgctctctac gaagctctga    420

agaagcttag aacatatgca gctattgagg acgaatatgt gcagcagaaa gatgagcagt    480

ttagggaatg gtttttgaaa gagtttcccc aagtcaagag gaagatccag gagtccatag    540

aaaagcttcg tgcccttgca aatggtattg aagaggtcca cagaggctgc accatctcca    600

atgtggtgtc cagctccact ggcgctgcct ctggcatcat gtcccttgct ggtcttgttt    660

tggcaccatt tacagcaggg acgagtctgg cccttactgc agctggggta gggctgggag    720

cagcgtctgc tgtgactggg atcaccacca gcatcgtgga gcactcatac acatcatcag    780

cagaagctga agccagcagg ctgactgcaa ccagcattga ccgattgaag gtatttaagg    840

aagttatgcg tgacatcaca cccaacttac tttcccttct taataattat tacgaagcca    900

cacaaaccat tgggagtgaa atccgtgcca tcaggcaagc cagagccagg gcccgactcc    960

ctgtgaccac ctggcgaatc tcagctggaa gtggtggtca agcagagaga acgattgcag   1020

gcaccacccg ggcagtgagc agaggagccc ggatcctgag tgcgaccact tcaggcatct   1080

tccttgcact ggatgtggtc aaccttgtat acgagtcaaa gcacttgcat gagggggcaa   1140

agtctgcatc tgctgaggag ctgaggcggc aggctcagga gctggaggag aatctaatgg   1200

agctcactca gatctatcag cgtctgaatc catgccatac ccactgaccc cagaccagtg   1260

cagccagcag gggaggtgag ccatacacag gccacgacaa aatgcaggca ttttattagg   1320

gggataaaga gggcaaggta aagtttatgg agctgagtgt tagtgacttt ggcatttctg   1380

tagctgagca cagcagggga ggggttaatg cagatggcaa gtgcaccaag gagaaggcag   1440

gaatgctgga gcctggaata agggaggaga ggggactgga gagtgtgggg aataggaaga   1500

agaaatttcc tttagactaa cgaatatatt ggggggagga atagagggga ggtgtgcagg   1560

aaccagcaat gagaaggcca ggaaaagaaa gagctgaaaa tgcagaaagc cgaagagtta   1620

gaacttttgg atacagcaga agaaacagcg gctccactac cgacctgccc ccggttcgat   1680

gtccttccaa gaatgaagtc tttccctggt gatggtcccc tgccctgtct ttccagcatc   1740

cactctgtct tgtcctcctg gaagtgtatc tcagtcagcc agtggcttct tgatgatggc   1800

ggtggaggtg gtggttgtag tgtgatggat cccctttagg ttatttaggg gtatatgtcc   1860

cctgcttgaa ccctgaaggc caggtaatga gccatggcca ttgtccccag ctgaggacca   1920

ggtgtctcta aaaacccaaa catcctggag agtatgcgag aacctaccaa gaaaaacagt   1980

ctcattactc atatacagca ggcaaagaga cagaaaatta actgaaaagc agtttagaga   2040

ctgggggagg ccggatctct agagccatcc tgctgagtgc cctgtgtgta agtcctaata   2100

aactcaccta ctcaccaag                                                2119


<210>  10464
<211>  402
<212>  PRT
<213>  Homo sapiens

<400>  10464

Met Gly Leu Gly Gln Gly Trp Gly Trp Glu Ala Ser Cys Phe Ala Cys 
1               5                   10                  15


Leu Ile Arg Ser Cys Cys Gln Val Val Thr Phe Thr Phe Pro Phe Gly 
            20                  25                  30


Phe Gln Gly Ile Ser Gln Ser Leu Glu Asn Val Ser Gly Tyr Tyr Ala 
        35                  40                  45


Asp Ala Arg Leu Glu Val Gly Ser Thr Gln Leu Arg Thr Ala Gly Ser 
    50                  55                  60


Cys Ser His Ser Phe Lys Arg Ser Phe Leu Glu Lys Lys Arg Phe Thr 
65                  70                  75                  80


Glu Glu Ala Thr Lys Tyr Phe Arg Glu Arg Val Ser Pro Val His Leu 
                85                  90                  95


Gln Ile Leu Leu Thr Asn Asn Glu Ala Trp Lys Arg Phe Val Thr Ala 
            100                 105                 110


Ala Glu Leu Pro Arg Asp Glu Ala Asp Ala Leu Tyr Glu Ala Leu Lys 
        115                 120                 125


Lys Leu Arg Thr Tyr Ala Ala Ile Glu Asp Glu Tyr Val Gln Gln Lys 
    130                 135                 140


Asp Glu Gln Phe Arg Glu Trp Phe Leu Lys Glu Phe Pro Gln Val Lys 
145                 150                 155                 160


Arg Lys Ile Gln Glu Ser Ile Glu Lys Leu Arg Ala Leu Ala Asn Gly 
                165                 170                 175


Ile Glu Glu Val His Arg Gly Cys Thr Ile Ser Asn Val Val Ser Ser 
            180                 185                 190


Ser Thr Gly Ala Ala Ser Gly Ile Met Ser Leu Ala Gly Leu Val Leu 
        195                 200                 205


Ala Pro Phe Thr Ala Gly Thr Ser Leu Ala Leu Thr Ala Ala Gly Val 
    210                 215                 220


Gly Leu Gly Ala Ala Ser Ala Val Thr Gly Ile Thr Thr Ser Ile Val 
225                 230                 235                 240


Glu His Ser Tyr Thr Ser Ser Ala Glu Ala Glu Ala Ser Arg Leu Thr 
                245                 250                 255


Ala Thr Ser Ile Asp Arg Leu Lys Val Phe Lys Glu Val Met Arg Asp 
            260                 265                 270


Ile Thr Pro Asn Leu Leu Ser Leu Leu Asn Asn Tyr Tyr Glu Ala Thr 
        275                 280                 285


Gln Thr Ile Gly Ser Glu Ile Arg Ala Ile Arg Gln Ala Arg Ala Arg 
    290                 295                 300


Ala Arg Leu Pro Val Thr Thr Trp Arg Ile Ser Ala Gly Ser Gly Gly 
305                 310                 315                 320


Gln Ala Glu Arg Thr Ile Ala Gly Thr Thr Arg Ala Val Ser Arg Gly 
                325                 330                 335


Ala Arg Ile Leu Ser Ala Thr Thr Ser Gly Ile Phe Leu Ala Leu Asp 
            340                 345                 350


Val Val Asn Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala Lys 
        355                 360                 365


Ser Ala Ser Ala Glu Glu Leu Arg Arg Gln Ala Gln Glu Leu Glu Glu 
    370                 375                 380


Asn Leu Met Glu Leu Thr Gln Ile Tyr Gln Arg Leu Asn Pro Cys His 
385                 390                 395                 400


Thr His 



<210>  10465
<211>  3628
<212>  DNA
<213>  Homo sapiens

<400>  10465
actctgggga aaggagggta caaccacatg taaattttat tataatgatg gtataatgaa     60

cttggggtga cctgagggca tgtttttgtg ttactgggca tgtgcccctt taggagactt    120

ccacctgtgc cttactttct ctttctttgg gatgtgctgg ccacagactt taccaaaaac    180

tccatccatt aggatggcat taggacggtt ctggggctaa acttaggtgg gccaggggct    240

gtttcactgt cagcctttct actctctttt cttacccact cctagctgct aatgtctatt    300

taactaccta atatttcccc ctttagagaa aaaaagccaa atttttgggt agatcggtga    360

caattaatct ggctacttcc tgctgacaag aggcagtggt aataattggg ttctcttttt    420

tgctctcttg tagctggtag gttgggcaga gaaaagtggt ggccatccaa ggggcccacg    480

tagatatcag acatggttga gacctcgcgg taaccttgtg tagaatcatt tggagtttta    540

tggattctag gtgggaagaa acaaaacaac cttgtaaatc aaatgagcat cgtttgaaag    600

ctataagttg tataaagctg ttttaggacc aagaaagggg gctaaccagg aaaaccagga    660

ccagttgtta aatttccacc agtcaaagcc tcctgaaact ctgttttcca ttaacttgtt    720

ggccctgtct gtaatttttt taagttggtt tgcactttac ctgattggtt gatgaaaaca    780

gcaatgttta tcaagtgttg cacaagctcc cccttgattg gctgtgagca aattaaaagc    840

tcatcaattt cataagacta tgcttgctaa tgaagcaatt tgttctgaaa gggtattgac    900

ctggttagtt agattaataa tttgttgagt aatttttaag aagagtttct gggcagtaaa    960

aatggagtta aggaggtcct ccagttcccg tgccaatacc agccagaacg ccaattatag   1020

tcagtgctgt taaaactcct ctttcagttt taccagattg agcgtgtata gggaggggaa   1080

tgctatcgat aagagtgagt ttggggatga tgtaaactag ggccaaatcc ccgtttaatt   1140

agcagacaag cagagatatg ccttgtttct atacaaaaat gtgatttgtc atgttaagac   1200

aaatatcaac agtgatacta aagtagggtt tttccatgct gtgtaagtct gctttaatac   1260

cctcagaagt ggaagtcaag gctagttcat gtaatggggg aacacaggca gtacttgaca   1320

gaatgaaaga ggaatcaaaa gcccaattag aggaaggagt gatgggatcc caaccaatat   1380

tgtgaaatta tggggagctg cagttttttg caatgatttt gcccgaagtt gtgagactga   1440

aaccagaagt tgttatgttt aaaatgatat tctggtgtgg gtctggggaa aagggtagat   1500

ccagaatagc tggcttcttt ccacatagtg gttctgttgg ggggcttggg aaatgaataa   1560

aacacaaaga agaattagaa tatcaggtga aggtagcagg tgctcctggc agaagaaccc   1620

acataaggaa gtgtccagaa gccacacagg gtatatctca gagcctggag aacgtgtctg   1680

gttattatgc agatgcacgg ctggaggtgg gatccacaca gctcagaaca gctggatctt   1740

gctcacactc tttcaagaga agcttccttg aaaagaaacg ctttactgaa gaggccacca   1800

aatacttccg ggagagagtc agcccagtgc atctgcaaat cctgctgact aacaatgaag   1860

cctggaagag attcgtgact gcggctgaat tgcccaggga tgaggcagat gctctctacg   1920

aagctctgaa gaagcttaga acatatgcag ctattgagga cgaatatgtg cagcagaaag   1980

atgagcagtt tagggaatgg tttttgaaag agtttcccca agtcaagagg aagatccagg   2040

agtccataga aaagcttcgt gcccttgcaa atggtattga agaggtccac agaggctgca   2100

ccatctccaa tgtggtgtcc agctccactg gcgctgcctc tggcatcatg tcccttgctg   2160

gtcttgtttt ggcaccattt acagcaggga cgagtctggc ccttactgca gctggggtag   2220

ggctgggagc agcgtctgct gtgactggga tcaccaccag catcgtggag cactcataca   2280

catcatcagc agaagctgaa gccagcaggc tgactgcaac cagcattgac cgattgaagg   2340

tatttaagga agttatgcgt gacatcacac ccaacttact ttcccttctt aataattatt   2400

acgaagccac acaaaccatt gggagtgaaa tccgtgccat caggcaagcc agagccaggg   2460

cccgactccc tgtgaccacc tggcgaatct cagctggaag tggtggtcaa gcagagagaa   2520

cgattgcagg caccacccgg gcagtgagca gaggagcccg gatcctgagt gcgaccactt   2580

caggcatctt ccttgcactg gatgtggtca accttgtata cgagtcaaag cacttgcatg   2640

agggggcaaa gtctgcatct gctgaggagc tgaggcggca ggctcaggag ctggaggaga   2700

atctaatgga gctcactcag atctatcagc gtctgaatcc atgccatacc cactgacccc   2760

agaccagtgc agccagcagg ggaggtgagc catacacagg ccacgacaaa atgcaggcat   2820

tttattaggg ggataaagag ggcaaggtaa agtttatgga gctgagtgtt agtgactttg   2880

gcatttctgt agctgagcac agcaggggag gggttaatgc agatggcaag tgcaccaagg   2940

agaaggcagg aatgctggag cctggaataa gggaggagag gggactggag agtgtgggga   3000

ataggaagaa gaaatttcct ttagactaac gaatatattg gggggaggaa tagaggggag   3060

gtgtgcagga accagcaatg agaaggccag gaaaagaaag agctgaaaat gcagaaagcc   3120

gaagagttag aacttttgga tacagcagaa gaaacagcgg ctccactacc gacctgcccc   3180

cggttcgatg tccttccaag aatgaagtct ttccctggtg atggtcccct gccctgtctt   3240

tccagcatcc actctgtctt gtcctcctgg aagtgtatct cagtcagcca gtggcttctt   3300

gatgatggcg gtggaggtgg tggttgtagt gtgatggatc ccctttaggt tatttagggg   3360

tatatgtccc ctgcttgaac cctgaaggcc aggtaatgag ccatggccat tgtccccagc   3420

tgaggaccag gtgtctctaa aaacccaaac atcctggaga gtatgcgaga acctaccaag   3480

aaaaacagtc tcattactca tatacagcag gcaaagagac agaaaattaa ctgaaaagca   3540

gtttagagac tgggggaggc cggatctcta gagccatcct gctgagtgcc ctgtgtgtaa   3600

gtcctaataa actcacctac tcaccaag                                      3628


<210>  10466
<211>  72
<212>  PRT
<213>  Homo sapiens

<400>  10466

Met Asn Lys Thr Gln Arg Arg Ile Arg Ile Ser Gly Glu Gly Ser Arg 
1               5                   10                  15


Cys Ser Trp Gln Lys Asn Pro His Lys Glu Val Ser Arg Ser His Thr 
            20                  25                  30


Gly Tyr Ile Ser Glu Pro Gly Glu Arg Val Trp Leu Leu Cys Arg Cys 
        35                  40                  45


Thr Ala Gly Gly Gly Ile His Thr Ala Gln Asn Ser Trp Ile Leu Leu 
    50                  55                  60


Thr Leu Phe Gln Glu Lys Leu Pro 
65                  70


<210>  10467
<211>  3565
<212>  DNA
<213>  Homo sapiens

<400>  10467
actctgggga aaggagggta caaccacatg taaattttat tataatgatg gtataatgaa     60

cttggggtga cctgagggca tgtttttgtg ttactgggca tgtgcccctt taggagactt    120

ccacctgtgc cttactttct ctttctttgg gatgtgctgg ccacagactt taccaaaaac    180

tccatccatt aggatggcat taggacggtt ctggggctaa acttaggtgg gccaggggct    240

gtttcactgt cagcctttct actctctttt cttacccact cctagctgct aatgtctatt    300

taactaccta atatttcccc ctttagagaa aaaaagccaa atttttgggt agatcggtga    360

caattaatct ggctacttcc tgctgacaag aggcagtggt aataattggg ttctcttttt    420

tgctctcttg tagctggtag gttgggcaga gaaaagtggt ggccatccaa ggggcccacg    480

tagatatcag acatggttga gacctcgcgg taaccttgtg tagaatcatt tggagtttta    540

tggattctag gtgggaagaa acaaaacaac cttgtaaatc aaatgagcat cgtttgaaag    600

ctataagttg tataaagctg ttttaggacc aagaaagggg gctaaccagg aaaaccagga    660

ccagttgtta aatttccacc agtcaaagcc tcctgaaact ctgttttcca ttaacttgtt    720

ggccctgtct gtaatttttt taagttggtt tgcactttac ctgattggtt gatgaaaaca    780

gcaatgttta tcaagtgttg cacaagctcc cccttgattg gctgtgagca aattaaaagc    840

tcatcaattt cataagacta tgcttgctaa tgaagcaatt tgttctgaaa gggtattgac    900

ctggttagtt agattaataa tttgttgagt aatttttaag aagagtttct gggcagtaaa    960

aatggagtta aggaggtcct ccagttcccg tgccaatacc agccagaacg ccaattatag   1020

tcagtgctgt taaaactcct ctttcagttt taccagattg agcgtgtata gggaggggaa   1080

tgctatcgat aagagtgagt ttggggatga tgtaaactag ggccaaatcc ccgtttaatt   1140

agcagacaag cagagatatg ccttgtttct atacaaaaat gtgatttgtc atgttaagac   1200

aaatatcaac agtgatacta aagtagggtt tttccatgct gtgtaagtct gctttaatac   1260

cctcagaagt ggaagtcaag gctagttcat gtaatggggg aacacaggca gtacttgaca   1320

gaatgaaaga ggaatcaaaa gcccaattag aggaaggagt gatgggatcc caaccaatat   1380

tgtgaaatta tggggagctg cagttttttg caatgatttt gcccgaagtt gtgagactga   1440

aaccagaagt tgttatgttt aaaatgatat tctggtgtgg gtctggggaa aagggtagat   1500

ccagaatagc tggcttcttt ccacatagtg gttctgttgg ggggcttggg aaatgaataa   1560

aacacaaaga agaattagaa tatcagggta tatctcagag cctggagaac gtgtctggtt   1620

attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct   1680

cacactcttt caagagaagc ttccttgaaa agaaacgctt tactgaagag gccaccaaat   1740

acttccggga gagagtcagc ccagtgcatc tgcaaatcct gctgactaac aatgaagcct   1800

ggaagagatt cgtgactgcg gctgaattgc ccagggatga ggcagatgct ctctacgaag   1860

ctctgaagaa gcttagaaca tatgcagcta ttgaggacga atatgtgcag cagaaagatg   1920

agcagtttag ggaatggttt ttgaaagagt ttccccaagt caagaggaag atccaggagt   1980

ccatagaaaa gcttcgtgcc cttgcaaatg gtattgaaga ggtccacaga ggctgcacca   2040

tctccaatgt ggtgtccagc tccactggcg ctgcctctgg catcatgtcc cttgctggtc   2100

ttgttttggc accatttaca gcagggacga gtctggccct tactgcagct ggggtagggc   2160

tgggagcagc gtctgctgtg actgggatca ccaccagcat cgtggagcac tcatacacat   2220

catcagcaga agctgaagcc agcaggctga ctgcaaccag cattgaccga ttgaaggtat   2280

ttaaggaagt tatgcgtgac atcacaccca acttactttc ccttcttaat aattattacg   2340

aagccacaca aaccattggg agtgaaatcc gtgccatcag gcaagccaga gccagggccc   2400

gactccctgt gaccacctgg cgaatctcag ctggaagtgg tggtcaagca gagagaacga   2460

ttgcaggcac cacccgggca gtgagcagag gagcccggat cctgagtgcg accacttcag   2520

gcatcttcct tgcactggat gtggtcaacc ttgtatacga gtcaaagcac ttgcatgagg   2580

gggcaaagtc tgcatctgct gaggagctga ggcggcaggc tcaggagctg gaggagaatc   2640

taatggagct cactcagatc tatcagcgtc tgaatccatg ccatacccac tgaccccaga   2700

ccagtgcagc cagcagggga ggtgagccat acacaggcca cgacaaaatg caggcatttt   2760

attaggggga taaagagggc aaggtaaagt ttatggagct gagtgttagt gactttggca   2820

tttctgtagc tgagcacagc aggggagggg ttaatgcaga tggcaagtgc accaaggaga   2880

aggcaggaat gctggagcct ggaataaggg aggagagggg actggagagt gtggggaata   2940

ggaagaagaa atttccttta gactaacgaa tatattgggg ggaggaatag aggggaggtg   3000

tgcaggaacc agcaatgaga aggccaggaa aagaaagagc tgaaaatgca gaaagccgaa   3060

gagttagaac ttttggatac agcagaagaa acagcggctc cactaccgac ctgcccccgg   3120

ttcgatgtcc ttccaagaat gaagtctttc cctggtgatg gtcccctgcc ctgtctttcc   3180

agcatccact ctgtcttgtc ctcctggaag tgtatctcag tcagccagtg gcttcttgat   3240

gatggcggtg gaggtggtgg ttgtagtgtg atggatcccc tttaggttat ttaggggtat   3300

atgtcccctg cttgaaccct gaaggccagg taatgagcca tggccattgt ccccagctga   3360

ggaccaggtg tctctaaaaa cccaaacatc ctggagagta tgcgagaacc taccaagaaa   3420

aacagtctca ttactcatat acagcaggca aagagacaga aaattaactg aaaagcagtt   3480

tagagactgg gggaggccgg atctctagag ccatcctgct gagtgccctg tgtgtaagtc   3540

ctaataaact cacctactca ccaag                                         3565


<210>  10468
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  10468

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Lys Arg Asn Ala 
            20                  25                  30


Leu Leu Lys Arg Pro Pro Asn Thr Ser Gly Arg Glu Ser Ala Gln Cys 
        35                  40                  45


Ile Cys Lys Ser Cys 
    50


<210>  10469
<211>  563
<212>  DNA
<213>  Homo sapiens

<400>  10469
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggac aaaaggaccc tgccttggtg tgagagtgag    120

ggcagaggga gctggagcaa gtagaatttc tctaaatacc agctggctgg ggcccaggag    180

attaaaaaac accgggctag gttggtcttg gcatttgctg acacgcaaag ggattgcaga    240

gatccagccc ctccaacctc cctctgtcca caggtggctc acattcagtc ccacaatttg    300

ctttctcctc ctcaagggtt aagaaaaaaa acgaaccctt ccagtcaggt cagtgactgg    360

agagctccat ggaaagtctc tcagtgacct ggctgctggc accatggact cagattttga    420

agacactggt gtaaagcgtt tgacaatagg cacatggcag aaggaagcga tcactggaat    480

atttcccgta catggggaga aagcatggtg gaaagctcac tttctggtga ttctcagctg    540

aaatagatcg gttcctccac aaa                                            563


<210>  10470
<211>  46
<212>  PRT
<213>  Homo sapiens

<400>  10470

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Asp Lys Arg Thr 
            20                  25                  30


Leu Pro Trp Cys Glu Ser Glu Gly Arg Gly Ser Trp Ser Lys 
        35                  40                  45


<210>  10471
<211>  589
<212>  DNA
<213>  Homo sapiens

<400>  10471
ttattatgca gatgcacggc tggaggtggg atccacacag ctcagaacag ctggatcttg     60

ctcacactct ttcaagagaa gcttccttgc gtggtggtat gtacctgtag ggacaactac    120

ttgggaagtt gaagcagaag catcacttgc agccaggaca tacaggcaga agcaaggggg    180

acaaagggtg tccagcacag caccagtgaa ttcaccaaga cagacacttg ggcatagagt    240

gcaagacaca gatttggaat gaggagtcat ttacaataag catgacaaaa ggaccctgcc    300

ttggtgtgag agtgagggca gagggagctg gagcaagtag aatttctcta aataccagct    360

ggctggggcc caggagatta aaaaacaccg ggctaggttg gtcttggcat ttgctgacac    420

gcaaagggat tgcagagatc cagcccctcc aacctccctc tgtccacagg tggctcacat    480

tcagtcccac aatttgcttt ctcctcctca agggttaaga aaaaaaacga acccttccag    540

tcaggtcagt gactggagag ctccatggaa agtctctcag tgacctggc                589


<210>  10472
<211>  78
<212>  PRT
<213>  Homo sapiens

<400>  10472

Met Thr Lys Gly Pro Cys Leu Gly Val Arg Val Arg Ala Glu Gly Ala 
1               5                   10                  15


Gly Ala Ser Arg Ile Ser Leu Asn Thr Ser Trp Leu Gly Pro Arg Arg 
            20                  25                  30


Leu Lys Asn Thr Gly Leu Gly Trp Ser Trp His Leu Leu Thr Arg Lys 
        35                  40                  45


Gly Ile Ala Glu Ile Gln Pro Leu Gln Pro Pro Ser Val His Arg Trp 
    50                  55                  60


Leu Thr Phe Ser Pro Thr Ile Cys Phe Leu Leu Leu Lys Gly 
65                  70                  75


<210>  10473
<211>  1219
<212>  DNA
<213>  Homo sapiens

<400>  10473
ggatttcagc caggctgtgc cacggagggc agaggccacc caggaggagg ccccacagcc     60

acttgcaggg agctgctttg ctgagagtct ctgtcctctg catctggaga gcttggctca    120

gagctgaggc aggagggagg gctccctgtc tgggcctcct ccaggaacta aagtcccttt    180

ccgggaattg accaaactgc aggcttgccc agggaggaca tgctgtgtcc tagttcagct    240

cgaggggcag tatccagctt caaccctcag cggatgcccc agacaagatt ccgagccagg    300

ccaacaacgc ctaaggagga cgagaccctg ggtgtagctc atcagaggtg tcaggtgtgg    360

tctgaggccc cagctctctc tgccctcctg ctcctctgct ctgtgctggc tcctggtcct    420

tatggctcat gatgttgaga cagctgccct ggcctagggg gtcacacact gaacaaagca    480

ggaagaaggg gaaggggagc cctccttcta tcacccttat cccttacagc aagaagcacc    540

cagaaacccc tcagcacact cccctagtgc ctctattggc ctcactgtca ccatggttgc    600

atgggggccc cagacaatag acacctggat gcaagatccc taagacagag gcaggaaata    660

ggaagaggga ggtgagaggc tttcgatgag gatgcttcta cacatgacct tgaggatgaa    720

aacgcatcag ggggtcccgg gaaccactgc gttgttaaca taaagtctgg gagcaaagac    780

cagcggctgg aatggatgtg cctgggagcc agctgaaaca gatgcagccg aagccacagt    840

aaagaagaaa gagatagggg cctgcttgga gccaacccct acctttgagg ggcctgacag    900

ggccacctca cagctgcctg ggcttgttgt tgcctcctca ctacagaaac catggaagtc    960

tctagagtca atgtttccag gctggggctg ccagatcact cctgtaggtg gttgaaccag   1020

ttgagttcat tcttctcagt gagggggaca caggtggagg tccatcggca cctccataag   1080

gggtgcgaga aggaacctgt tagaatatct gggttctggc tgggtgattg gcaggagggc   1140

ctatgaaatg gagcccactc tggattgggt gttgcagaaa gtggggggca agtctaccag   1200

tgggtatctc agcaaatct                                                1219


<210>  10474
<211>  70
<212>  PRT
<213>  Homo sapiens

<400>  10474

Met Leu Cys Pro Ser Ser Ala Arg Gly Ala Val Ser Ser Phe Asn Pro 
1               5                   10                  15


Gln Arg Met Pro Gln Thr Arg Phe Arg Ala Arg Pro Thr Thr Pro Lys 
            20                  25                  30


Glu Asp Glu Thr Leu Gly Val Ala His Gln Arg Cys Gln Val Trp Ser 
        35                  40                  45


Glu Ala Pro Ala Leu Ser Ala Leu Leu Leu Leu Cys Ser Val Leu Ala 
    50                  55                  60


Pro Gly Pro Tyr Gly Ser 
65                  70


<210>  10475
<211>  544
<212>  DNA
<213>  Homo sapiens

<400>  10475
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggta agttaggggt ggtctgacct tccccatctc    120

cccatcctca cagcagctct ataagagaag ggtcattcac cttttgtaga tgagctcaga    180

gaggttaggt aactgactga ggtcacatct cggtccatgg cagagcctga atttgcaccc    240

aggttttagc tggacttctc cctccctctc tctgggcccc caaacagtag agacagaggc    300

agaatcagct cagctgggtt cacaaagctt cctagggctc agctctagtt ccagcctgcg    360

tgagacatgg cccggtgacc ccagaaggaa ggcagatgtt gggactgtcc attcctttag    420

aatatttgga ggaaccagag aagtgctggg attacaggca tgagccaccg tgccaggcgc    480

attccttagt cttaatgggc atagtgttag ggacccgcct actccctatg gcaggagatt    540

tagt                                                                 544


<210>  10476
<211>  48
<212>  PRT
<213>  Homo sapiens

<400>  10476

Met Leu Gly Leu Ser Ile Pro Leu Glu Tyr Leu Glu Glu Pro Glu Lys 
1               5                   10                  15


Cys Trp Asp Tyr Arg His Glu Pro Pro Cys Gln Ala His Ser Leu Val 
            20                  25                  30


Leu Met Gly Ile Val Leu Gly Thr Arg Leu Leu Pro Met Ala Gly Asp 
        35                  40                  45


<210>  10477
<211>  538
<212>  DNA
<213>  Homo sapiens

<400>  10477
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggcc tctgggtgat agagaagaaa gaagctgtgc    120

tgttccctag tgggaaagat ggcccagaca ggggcagtga gaacggcatg ttgcagaatg    180

gtgtctgcca catgatccca gcttgacaat catgagatta aaagtcaaac tgtggaagcg    240

tgagcataac tgtgggagcg tgagcttagc cctctgtgtt tgtagaagca gaaacaaacc    300

tggaagattt tggattatta acattatact ttcttgcttc aatgtcagag tcaggaggtc    360

aggtgttgac cttccccctg ccctccaaga ggtgtgtgac actggggaag tcacttcccc    420

tctctgagcc tcagggtttt tcacctgcct tagggggtta ggatgcccta ccctgctgac    480

ccccagcagg ctgctgaccc catctggggt gaggtgggag gcggggcagt gcgagtca      538


<210>  10478
<211>  31
<212>  PRT
<213>  Homo sapiens

<400>  10478

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Ala Ser Gly 
            20                  25                  30


<210>  10479
<211>  288
<212>  DNA
<213>  Homo sapiens

<400>  10479
attatgcaga tgcacggctg gaggtgggat ccacacagct cagaacagct ggatcttgct     60

cacactcttt caagagaagc ttccttggta agttaggggt ggtctgacct tccccatccc    120

caaacagtag agacagaggc agaatcagct cagctgggtt cacaaagctt cctagggctc    180

agctctagtt ccagcctgcg tgagacatgg cccggtgacc ccagaaggaa ggcagatgtt    240

gggactgtcc attcctttag aatatttgga ggaaccagag aaggtgga                 288


<210>  10480
<211>  30
<212>  PRT
<213>  Homo sapiens

<400>  10480

Met Gln Met His Gly Trp Arg Trp Asp Pro His Ser Ser Glu Gln Leu 
1               5                   10                  15


Asp Leu Ala His Thr Leu Ser Arg Glu Ala Ser Leu Val Ser 
            20                  25                  30


<210>  10481
<211>  3801
<212>  DNA
<213>  Homo sapiens

<400>  10481
gaggaaaggc tgtctccacc cacctctcgc actctccctt ctcctttata aaggccggaa     60

cagctgaaag ggtggcaact tctcctcctg cagccgggag cggcctgcct gcctccctgc    120

gcacccgcag cctcccccgc tgcctcccta gggctcccct ccggccgcca gcgcccattt    180

ttcattccct agatagagat actttgcgcg cacacacata catacgcgcg caaaaaggaa    240

aaaaaaaaaa aaaagcccac cctccagcct cgctgcaaag agaaaaccgg agcagccgca    300

gctcgcagct cgcagctcgc agcccgcagc ccgcagagga cgcccagagc ggcgagcggg    360

cgggcagacg gaccgacgga ctcgcgccgc gtccacctgt cggccgggcc cagccgagcg    420

cgcagcgggc acgccgcgcg cgcggagcag ccgtgcccgc cgcccgggcc ccgcgccagg    480

gcgcacacgc tcccgccccc ctacccggcc cgggcgggag tttgcacctc tccctgcccg    540

ggtgctcgag ctgccgttgc aaagccaact ttggaaaaag ttttttgggg gagacttggg    600

ccttgaggtg cccagctccg cgctttccga ttttgggggc ctttccagaa aatgttgcaa    660

aaaagctaag ccggcgggca gaggaaaacg cctgtagccg gcgagtgaag acgaaccatc    720

gactgccgtg ttccttttcc tcttggaggt tggagtcccc tgggcgcccc cacacggcta    780

gacgcctcgg ctggttcgcg acgcagcccc ccggccgtgg atgctcactc gggctcggga    840

tccgcccagg tagcggcctc ggacccaggt cctgcgccca ggtcctcccc tgccccccag    900

cgacggagcc ggggccgggg gcggcggcgc ccgggggcca tgcgggtgag ccgcggctgc    960

agaggcctga gcgcctgatc gccgcggacc cgagccgagc ccacccccct ccccagcccc   1020

ccaccctggc cgcgggggcg gcgcgctcga tctacgcgtc cggggccccg cggggccggg   1080

cccggagtcg gcatgaatcg ctgctgggcg ctcttcctgt ctctctgctg ctacctgcgt   1140

ctggtcagcg ccgaggggga ccccattccc gaggagcttt atgagatgct gagtgaccac   1200

tcgatccgct cctttgatga tctccaacgc ctgctgcacg gagaccccgg agaggaagat   1260

ggggccgagt tggacctgaa catgacccgc tcccactctg gaggcgagct ggagagcttg   1320

gctcgtggaa gaaggagcct gggttccctg accattgctg agccggccat gatcgccgag   1380

tgcaagacgc gcaccgaggt gttcgagatc tcccggcgcc tcatagaccg caccaacgcc   1440

aacttcctgg tgtggccgcc ctgtgtggag gtgcagcgct gctccggctg ctgcaacaac   1500

cgcaacgtgc agtgccgccc cacccaggtg cagctgcgac ctgtccaggt gagaaagatc   1560

gagattgtgc ggaagaagcc aatctttaag aaggccacgg tgacgctgga agaccacctg   1620

gcatgcaagt gtgagacagt ggcagctgca cggcctgtga cccgaagccc ggggggttcc   1680

caggagcagc gagccaaaac gccccaaact cgggtgacca ttcggacggt gcgagtccgc   1740

cggcccccca agggcaagca ccggaaattc aagcacacgc atgacaagac ggcactgaag   1800

gagacccttg gagcctaggg gcatcggcag gagagtgtgt gggcagggtt atttaatatg   1860

gtatttgctg tattgccccc atggggtcct tggagtgata atattgtttc cctcgtccgt   1920

ctgtctcgat gcctgattcg gacggccaat ggtgcttccc ccacccctcc acgtgtccgt   1980

ccacccttcc atcagcgggt ctcctcccag cggcctccgg cgtcttgccc agcagctcaa   2040

gaagaaaaag aaggactgaa ctccatcgcc atcttcttcc cttaactcca agaacttggg   2100

ataagagtgt gagagagact gatggggtcg ctctttgggg gaaacgggct ccttcccctg   2160

cacctggcct gggccacacc tgagcgctgt ggactgtcct gaggagccct gaggacctct   2220

cagcatagcc tgcctgatcc ctgaacccct ggccagctct gaggggaggc acctccaggc   2280

aggccaggct gcctcggact ccatggctaa gaccacagac gggcacacag actggagaaa   2340

acccctccca cggtgcccaa acaccagtca cctcgtctcc ctggtgcctc tgtgcacagt   2400

ggcttctttt cgttttcgtt ttgaagacgt ggactcctct tggtgggtgt ggccagcaca   2460

ccaagtggct gggtgccctc tcaggtgggt tagagatgga gtttgctgtt gaggtggctg   2520

tagatggtga cctgggtatc ccctgcctcc tgccacccct tcctccccac actccactct   2580

gattcacctc ttcctctggt tcctttcatc tctctacctc caccctgcat tttcctcttg   2640

tcctggccct tcagtctgct ccaccaaggg gctcttgaac cccttattaa ggccccagat   2700

gatcccagtc actcctctct agggcagaag actagaggcc agggcagcaa gggacctgct   2760

catcatattc caacccagcc acgactgcca tgtaaggttg tgcagggtgt gtactgcaca   2820

aggacattgt atgcagggag cactgttcac atcatagata aagctgattt gtatatttat   2880

tatgacaatt tctggcagat gtaggtaaag aggaaaagga tccttttcct aattcacaca   2940

aagactcctt gtggactggc tgtgcccctg atgcagcctg tggcttggag tggccaaata   3000

ggagggagac tgtggtaggg gcagggaggc aacactgctg tccacatgac ctccatttcc   3060

caaagtcctc tgctccagca actgcccttc caggtgggtg tgggacacct gggagaaggt   3120

ctccaaggga gggtgcagcc ctcttgcccg cacccctccc tgcttgcaca cttccccatc   3180

tttgatcctt ctgagctcca cctctggtgg ctcctcctag gaaaccagct cgtgggctgg   3240

gaatggggga gagaagggaa aagatcccca agaccccctg gggtgggatc tgagctccca   3300

cctcccttcc cacctactgc actttccccc ttcccgcctt ccaaaacctg cttccttcag   3360

tttgtaaagt cggtgattat atttttgggg gctttccttt tattttttaa atgtaaaatt   3420

tatttatatt ccgtatttaa agttgtaaaa aaaaataacc acaaaacaaa accaaatgaa   3480

tccgccggag gtctgtctgt tggcatcgtg cgtgacaatt aacctttctg ccttggcagg   3540

atgtgccgac agcttgcggc gtgttcctct cactctggga gcctcaggcg tgatctcaca   3600

cactggcgtg cacatacaca cacacacaca tacatgctca cacatgcgtg cacatacacg   3660

caggcctgca acttggggga ggcctctgtc tggcgggaag aagagacaca caggctactc   3720

tgttggtctt ggtcctggca cagctcctga cacgtggact tgtgcgtgtc tctggcagtg   3780

acgagagatg ggtttctgca g                                             3801


<210>  10482
<211>  241
<212>  PRT
<213>  Homo sapiens

<400>  10482

Met Asn Arg Cys Trp Ala Leu Phe Leu Ser Leu Cys Cys Tyr Leu Arg 
1               5                   10                  15


Leu Val Ser Ala Glu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu Met 
            20                  25                  30


Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu Leu 
        35                  40                  45


His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn Met 
    50                  55                  60


Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly Arg 
65                  70                  75                  80


Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala Glu 
                85                  90                  95


Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile Asp 
            100                 105                 110


Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val Gln 
        115                 120                 125


Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro Thr 
    130                 135                 140


Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val Arg 
145                 150                 155                 160


Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His Leu 
                165                 170                 175


Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg Ser 
            180                 185                 190


Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg Val 
        195                 200                 205


Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His Arg 
    210                 215                 220


Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu Gly 
225                 230                 235                 240


Ala 



<210>  10483
<211>  2542
<212>  DNA
<213>  Homo sapiens

<400>  10483
gtgtgtgtgt gtgtgcgcat ctgagagaga gagagagaga gactgactga gcaggaatgg     60

tgagatgttt atcatgggcc tcggggaccc cattcccgag gagctttatg agatgctgag    120

tgaccactcg atccgctcct ttgatgatct ccaacgcctg ctgcacggag accccggaga    180

ggaagatggg gccgagttgg acctgaacat gacccgctcc cactctggag gcgagctgga    240

gagcttggct cgtggaagaa ggagcctggg ttccctgacc attgctgagc cggccatgat    300

cgccgagtgc aagacgcgca ccgaggtgtt cgagatctcc cggcgcctca tagaccgcac    360

caacgccaac ttcctggtgt ggccgccctg tgtggaggtg cagcgctgct ccggctgctg    420

caacaaccgc aacgtgcagt gccgccccac ccaggtgcag ctgcgacctg tccaggtgag    480

aaagatcgag attgtgcgga agaagccaat ctttaagaag gccacggtga cgctggaaga    540

ccacctggca tgcaagtgtg agacagtggc agctgcacgg cctgtgaccc gaagcccggg    600

gggttcccag gagcagcgag ccaaaacgcc ccaaactcgg gtgaccattc ggacggtgcg    660

agtccgccgg ccccccaagg gcaagcaccg gaaattcaag cacacgcatg acaagacggc    720

actgaaggag acccttggag cctaggggca tcggcaggag agtgtgtggg cagggttatt    780

taatatggta tttgctgtat tgcccccatg gggtccttgg agtgataata ttgtttccct    840

cgtccgtctg tctcgatgcc tgattcggac ggccaatggt gcttccccca cccctccacg    900

tgtccgtcca cccttccatc agcgggtctc ctcccagcgg cctccggcgt cttgcccagc    960

agctcaagaa gaaaaagaag gactgaactc catcgccatc ttcttccctt aactccaaga   1020

acttgggata agagtgtgag agagactgat ggggtcgctc tttgggggaa acgggctcct   1080

tcccctgcac ctggcctggg ccacacctga gcgctgtgga ctgtcctgag gagccctgag   1140

gacctctcag catagcctgc ctgatccctg aacccctggc cagctctgag gggaggcacc   1200

tccaggcagg ccaggctgcc tcggactcca tggctaagac cacagacggg cacacagact   1260

ggagaaaacc cctcccacgg tgcccaaaca ccagtcacct cgtctccctg gtgcctctgt   1320

gcacagtggc ttcttttcgt tttcgttttg aagacgtgga ctcctcttgg tgggtgtggc   1380

cagcacacca agtggctggg tgccctctca ggtgggttag agatggagtt tgctgttgag   1440

gtggctgtag atggtgacct gggtatcccc tgcctcctgc caccccttcc tccccacact   1500

ccactctgat tcacctcttc ctctggttcc tttcatctct ctacctccac cctgcatttt   1560

cctcttgtcc tggcccttca gtctgctcca ccaaggggct cttgaacccc ttattaaggc   1620

cccagatgat cccagtcact cctctctagg gcagaagact agaggccagg gcagcaaggg   1680

acctgctcat catattccaa cccagccacg actgccatgt aaggttgtgc agggtgtgta   1740

ctgcacaagg acattgtatg cagggagcac tgttcacatc atagataaag ctgatttgta   1800

tatttattat gacaatttct ggcagatgta ggtaaagagg aaaaggatcc ttttcctaat   1860

tcacacaaag actccttgtg gactggctgt gcccctgatg cagcctgtgg cttggagtgg   1920

ccaaatagga gggagactgt ggtaggggca gggaggcaac actgctgtcc acatgacctc   1980

catttcccaa agtcctctgc tccagcaact gcccttccag gtgggtgtgg gacacctggg   2040

agaaggtctc caagggaggg tgcagccctc ttgcccgcac ccctccctgc ttgcacactt   2100

ccccatcttt gatccttctg agctccacct ctggtggctc ctcctaggaa accagctcgt   2160

gggctgggaa tgggggagag aagggaaaag atccccaaga ccccctgggg tgggatctga   2220

gctcccacct cccttcccac ctactgcact ttcccccttc ccgccttcca aaacctgctt   2280

ccttcagttt gtaaagtcgg tgattatatt tttgggggct ttccttttat tttttaaatg   2340

taaaatttat ttatattccg tatttaaagt tgtaaaaaaa aataaccaca aaacaaaacc   2400

aaatgaatcc gccggaggtc tgtctgttgg catcgtgcgt gacaattaac ctttctgcct   2460

tggcaggatg tgccgacagc ttgcggcgtg ttcctctcac tctgggagcc tcaggcgtga   2520

tctcacacac tggcgtgcac at                                            2542


<210>  10484
<211>  226
<212>  PRT
<213>  Homo sapiens

<400>  10484

Met Phe Ile Met Gly Leu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu 
1               5                   10                  15


Met Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu 
            20                  25                  30


Leu His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn 
        35                  40                  45


Met Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly 
    50                  55                  60


Arg Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala 
65                  70                  75                  80


Glu Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile 
                85                  90                  95


Asp Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val 
            100                 105                 110


Gln Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro 
        115                 120                 125


Thr Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val 
    130                 135                 140


Arg Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His 
145                 150                 155                 160


Leu Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg 
                165                 170                 175


Ser Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg 
            180                 185                 190


Val Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His 
        195                 200                 205


Arg Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu 
    210                 215                 220


Gly Ala 
225


<210>  10485
<211>  2405
<212>  DNA
<213>  Homo sapiens

<400>  10485
gtgtgtgtgt gtgtgcgcat ctgagagaga gagagagaga gactgactga gcaggaatgg     60

tgagatgttt atcatgggcc tcggggaccc cattcccgag gagctttatg agatgctgag    120

tgaccactcg atccgctcct ttgatgatct ccaacgcctg ctgcacggag accccggaga    180

ggaagatggg gccgagttgg acctgaacat gacccgctcc cactctggag gcgagctgga    240

gagcttggct cgtggaagaa ggagcctggg ttccctgacc attgctgagc cggccatgat    300

cgccgagtgc aagacgcgca ccgaggtgtt cgagatctcc cggcgcctca tagaccgcac    360

caacgccaac ttcctggtgt ggccgccctg tgtggaggtg cagcgctgct ccggctgctg    420

caacaaccgc aacgtgcagt gccgccccac ccaggtgcag ctgcgacctg tccaggtgag    480

aaagatcgag attgtgcgga agaagccaat ctttaagaag gccacggtga cgctggaaga    540

ccacctggca tgcaagtgtg agacagtggc agctgcacgg cctgtgaccc gaagcccggg    600

gggttcccag gagcagcgag ccaaaacgcc ccaaactcgg gtgaccattc ggacggtgcg    660

agtccgccgg ccccccaagg gcaagcaccg gaaattcaag cacacgcatg acaagacggc    720

actgaaggag acccttggag cctaggggca tcggcaggag agtgtgtggg cagggttatt    780

taatatggta tttgctgtat tgcccccatg gggtccttgg agtgataata ttgtttccct    840

cgtccgtctg tctcgatgcc tgattcggac ggccaatggt gcttccccca cccctccacg    900

tgtccgtcca cccttccatc agcgggtctc ctcccagcgg cctccggcgt cttgcccagc    960

agctcaagaa gaaaaagaag gactgaactc catcgccatc ttcttccctt aactccaaga   1020

acttgggata agagtgtgag agagactgat ggggtcgctc tttgggggaa acgggctcct   1080

tcccctgcac ctggcctggg ccacacctga gcgctgtgga ctgtcctgag gagccctgag   1140

gacctctcag catagcctgc ctgatccctg aacccctggc cagctctgag gggaggcacc   1200

tccaggcagg ccaggctgcc tcggactcca tggctaagac cacagacggg cacacagact   1260

ggagaaaacc cctcccacgg tgcccaaaca ccagtcacct cgtctccctg gtgcctctgt   1320

gcacagtggc ttcttttcgt tttcgttttg aagacgtgga ctcctcttgg tgggtgtggc   1380

cagcacacca agtggctggg tgccctctca ggtgggttag agatggagtt tgctgttgag   1440

gtggctgtag atggtgacct gggtatcccc tgcctcctgc caccccttcc tccccacact   1500

ccactctgat tcacctcttc ctctggttcc tttcatctct ctacctccac cctgcatttt   1560

cctcttgtcc tggcccttca gtctgctcca ccaaggggct cttgaacccc ttattaaggc   1620

cccagatgat cccagtcact cctctctagg gcagaagact agaggccagg gcagcaaggg   1680

acctgctcat catattccaa cccagccacg actgccatgt aaggttgtgc agggtgtgta   1740

ctgcacaagg acattgtatg cagggagcac tgttcacatc atagataaag ctgatttgta   1800

tatttattat gacaatttct ggcagatgta ggtaaagagg aaaaggatcc ttttcctaat   1860

tcacacaaag actccttgtg gactggctgt gcccctgatg cagcctgtgg cttggagtgg   1920

ccaaatagga gggagactgt ggtaggggca gggaggcaac actgctgtcc acatgacctc   1980

catttcccaa agtcctctgc tccagcaact gcccttccag gtgggtgtgg gacacctggg   2040

agaaggtctc caagggaggg tgcagccctc ttgcccgcac ccctccctgc ttgcacactt   2100

ccccatcttt gatccttctg agctccacct ctggtggctc ctcctaggaa accagctcgt   2160

gggctgggaa tgggggagag aagggaaaag atccccaaga ccccctgggg tgggatctga   2220

gctcccacct cccttcccac ctactgcact ttcccccttc ccgccttcca aaacctgctt   2280

ccttcagttt gtaaagtcgg tgattatatt tttgggggct ttccttttat tttttaaatg   2340

taaaatttat ttatattccg tatttaaagt tgtaaaaaaa aataaccaca aaacaaaacc   2400

aaatg                                                               2405


<210>  10486
<211>  226
<212>  PRT
<213>  Homo sapiens

<400>  10486

Met Phe Ile Met Gly Leu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu 
1               5                   10                  15


Met Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu 
            20                  25                  30


Leu His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn 
        35                  40                  45


Met Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly 
    50                  55                  60


Arg Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala 
65                  70                  75                  80


Glu Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile 
                85                  90                  95


Asp Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val 
            100                 105                 110


Gln Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro 
        115                 120                 125


Thr Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val 
    130                 135                 140


Arg Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His 
145                 150                 155                 160


Leu Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg 
                165                 170                 175


Ser Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg 
            180                 185                 190


Val Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His 
        195                 200                 205


Arg Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu 
    210                 215                 220


Gly Ala 
225


<210>  10487
<211>  3408
<212>  DNA
<213>  Homo sapiens

<400>  10487
ggtggcaact tctcctcctg cagccgggag cggcctgcct gcctccctgc gcacccgcag     60

cctcccccgc tgcctcccta gggctcccct ccggccgcca gcgcccattt ttcattccct    120

agatagagat actttgcgcg cacacacata catacgcgcg caaaaaggaa aaaaaaaaaa    180

aaaagcccac cctccagcct cgctgcaaag agaaaaccgg agcagccgca gctcgcagct    240

cgcagctcgc agcccgcagc ccgcagagga cgcccagagc ggcgagcggg cgggcagacg    300

gaccgacgga ctcgcgccgc gtccacctgt cggccgggcc cagccgagcg cgcagcgggc    360

acgccgcgcg cgcggagcag ccgtgcccgc cgcccgggcc ccgcgccagg gcgcacacgc    420

tcccgccccc ctacccggcc cgggcgggag tttgcacctc tccctgcccg ggtgctcgag    480

ctgccgttgc aaagccaact ttggaaaaag ttttttgggg gagacttggg ccttgaggtg    540

cccagctccg cgctttccga ttttgggggc ctttccagaa aatgttgcaa aaaagctaag    600

ccggcgggca gaggaaaacg cctgtagccg gcgagtgaag acgaaccatc gactgccgtg    660

ttccttttcc tcttggaggt tggagtcccc tgggcgcccc cacacggcta gacgcctcgg    720

ctggttcgcg acgcagcccc ccggccgtgg atgctcactc gggctcggga tccgcccagg    780

tagcggcctc ggacccaggt cctgcgccca ggtcctcccc tgccccccag cgacggagcc    840

ggggccgggg gcggcggcgc ccgggggcca tgcgggtgag ccgcggctgc agaggcctga    900

gcgcctgatc gccgcggacc cgagccgagc ccacccccct ccccagcccc ccaccctggc    960

cgcgggggcg gcgcgctcga tctacgcgtc cggggccccg cggggccggg cccggagtcg   1020

gcatgaatcg ctgctgggcg ctcttcctgt ctctctgctg ctacctgcgt ctggtcagcg   1080

ccgaggggga ccccattccc gaggagcttt atgagatgct gagtgaccac tcgatccgct   1140

cctttgatga tctccaacgc ctgctgcacg gagaccccgg agaggaagat ggggccgagt   1200

tggacctgaa catgacccgc tcccactctg gaggcgagct ggagagcttg gctcgtggaa   1260

gaaggagcct gggttccctg accattgctg agccggccat gatcgccgag tgcaagacgc   1320

gcaccgaggt gttcgagatc tcccggcgcc tcatagaccg caccaacgcc aacttcctgg   1380

tgtggccgcc ctgtgtggag gtgcagcgct gctccggctg ctgcaacaac cgcaacgtgc   1440

agtgccgccc cacccaggtg cagctgcgac ctgtccaggt gagaaagatc gagattgtgc   1500

ggaagaagcc aatctttaag aaggccacgg tgacgctgga agaccacctg gcatgcaagt   1560

gtgagacagt ggcagctgca cggcctgtga cccgaagccc ggggggttcc caggagcagc   1620

gagccaaaac gccccaaact cgggtgacca ttcggacggt gcgagtccgc cggcccccca   1680

agggcaagca ccggaaattc aagcacacgc atgacaagac ggcactgaag gagacccttg   1740

gagcctaggg gcatcggcag gagagtgtgt gggcagggtt atttaatatg gtatttgctg   1800

tattgccccc atggggtcct tggagtgata atattgtttc cctcgtccgt ctgtctcgat   1860

gcctgattcg gacggccaat ggtgcttccc ccacccctcc acgtgtccgt ccacccttcc   1920

atcagcgggt ctcctcccag cggcctccgg cgtcttgccc agcagctcaa gaagaaaaag   1980

aaggactgaa ctccatcgcc atcttcttcc cttaactcca agaacttggg ataagagtgt   2040

gagagagact gatggggtcg ctctttgggg gaaacgggct ccttcccctg cacctggcct   2100

gggccacacc tgagcgctgt ggactgtcct gaggagccct gaggacctct cagcatagcc   2160

tgcctgatcc ctgaacccct ggccagctct gaggggaggc acctccaggc aggccaggct   2220

gcctcggact ccatggctaa gaccacagac gggcacacag actggagaaa acccctccca   2280

cggtgcccaa acaccagtca cctcgtctcc ctggtgcctc tgtgcacagt ggcttctttt   2340

cgttttcgtt ttgaagacgt ggactcctct tggtgggtgt ggccagcaca ccaagtggct   2400

gggtgccctc tcaggtgggt tagagatgga gtttgctgtt gaggtggctg tagatggtga   2460

cctgggtatc ccctgcctcc tgccacccct tcctccccac actccactct gattcacctc   2520

ttcctctggt tcctttcatc tctctacctc caccctgcat tttcctcttg tcctggccct   2580

tcagtctgct ccaccaaggg gctcttgaac cccttattaa ggccccagat gatcccagtc   2640

actcctctct agggcagaag actagaggcc agggcagcaa gggacctgct catcatattc   2700

caacccagcc acgactgcca tgtaaggttg tgcagggtgt gtactgcaca aggacattgt   2760

atgcagggag cactgttcac atcatagata aagctgattt gtatatttat tatgacaatt   2820

tctggcagat gtaggtaaag aggaaaagga tccttttcct aattcacaca aagactcctt   2880

gtggactggc tgtgcccctg atgcagcctg tggcttggag tggccaaata ggagggagac   2940

tgtggtaggg gcagggaggc aacactgctg tccacatgac ctccatttcc caaagtcctc   3000

tgctccagca actgcccttc caggtgggtg tgggacacct gggagaaggt ctccaaggga   3060

gggtgcagcc ctcttgcccg cacccctccc tgcttgcaca cttccccatc tttgatcctt   3120

ctgagctcca cctctggtgg ctcctcctag gaaaccagct cgtgggctgg gaatggggga   3180

gagaagggaa aagatcccca agaccccctg gggtgggatc tgagctccca cctcccttcc   3240

cacctactgc actttccccc ttcccgcctt ccaaaacctg cttccttcag tttgtaaagt   3300

cggtgattat atttttgggg gctttccttt tattttttaa atgtaaaatt tatttatatt   3360

ccgtatttaa agttgtaaaa aaaaataacc acaaaacaaa accaaatg                3408


<210>  10488
<211>  241
<212>  PRT
<213>  Homo sapiens

<400>  10488

Met Asn Arg Cys Trp Ala Leu Phe Leu Ser Leu Cys Cys Tyr Leu Arg 
1               5                   10                  15


Leu Val Ser Ala Glu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu Met 
            20                  25                  30


Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu Leu 
        35                  40                  45


His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn Met 
    50                  55                  60


Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly Arg 
65                  70                  75                  80


Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala Glu 
                85                  90                  95


Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile Asp 
            100                 105                 110


Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val Gln 
        115                 120                 125


Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro Thr 
    130                 135                 140


Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val Arg 
145                 150                 155                 160


Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His Leu 
                165                 170                 175


Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg Ser 
            180                 185                 190


Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg Val 
        195                 200                 205


Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His Arg 
    210                 215                 220


Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu Gly 
225                 230                 235                 240


Ala 



<210>  10489
<211>  1968
<212>  DNA
<213>  Homo sapiens

<400>  10489
ggcaacttct cctcctgcag ccgggagcgg cctgcctgcc tccctgcgca cccgcagcct     60

cccccgctgc ctccctaggg ctcccctccg gccgccagcg cccatttttc attccctaga    120

tagagatact ttgcgcgcac acacatacat acgcgcgcaa aaaggaaaaa aaaaaaaaaa    180

agcccaccct ccagcctcgc tgcaaagaga aaaccggagc agccgcagct cgcagctcgc    240

agctcgcagc ccgcagcccg cagaggacgc ccagagcggc gagcgggcgg gcagacggac    300

cgacggactc gcgccgcgtc cacctgtcgg ccgggcccag ccgagcgcgc agcgggcacg    360

ccgcgcgcgc ggagcagccg tgcccgccgc ccgggccccg cgccagggcg cacacgctcc    420

cgccccccta cccggcccgg gcgggagttt gcacctctcc ctgcccgggt gctcgagctg    480

ccgttgcaaa gccaactttg gaaaaagttt tttgggggag acttgggcct tgaggtgccc    540

agctccgcgc tttccgattt tgggggcctt tccagaaaat gttgcaaaaa agctaagccg    600

gcgggcagag gaaaacgcct gtagccggcg agtgaagacg aaccatcgac tgccgtgttc    660

cttttcctct tggaggttgg agtcccctgg gcgcccccac acggctagac gcctcggctg    720

gttcgcgacg cagccccccg gccgtggatg ctcactcggg ctcgggatcc gcccaggtag    780

cggcctcgga cccaggtcct gcgcccaggt cctcccctgc cccccagcga cggagccggg    840

gccgggggcg gcggcgcccg ggggccatgc gggtgagccg cggctgcaga ggcctgagcg    900

cctgatcgcc gcggacccga gccgagccca cccccctccc cagcccccca ccctggccgc    960

gggggcggcg cgctcgatct acgcgtccgg ggccccgcgg ggccgggccc ggagtcggca   1020

tgaatcgctg ctgggcgctc ttcctgtctc tctgctgcta cctgcgtctg gtcagcgccg   1080

agggggaccc cattcccgag gagctttatg agatgctgag tgaccactcg atccgctcct   1140

ttgatgatct ccaacgcctg ctgcacggag accccggaga ggaagatggg gccgagttgg   1200

acctgaacat gacccgctcc cactctggag gcgagctgga gagcttggct cgtggaagaa   1260

ggagcctggg ttccctgacc attgctgagc cggccatgat cgccgagtgc aagacgcgca   1320

ccgaggtgtt cgagatctcc cggcgcctca tagaccgcac caacgccaac ttcctggtgt   1380

ggccgccctg tgtggaggtg cagcgctgct ccggctgctg caacaaccgc aacgtgcagt   1440

gccgccccac ccaggtgcag ctgcgacctg tccaggtgag aaagatcgag attgtgcgga   1500

agaagccaat ctttaagaag gccacggtga cgctggaaga ccacctggca tgcaagtgtg   1560

agacagtggc agctgcacgg cctgtgaccc gaagcccggg gggttcccag gagcagcgag   1620

ccaaaacgcc ccaaactcgg gtgaccattc ggacggtgcg agtccgccgg ccccccaagg   1680

gcaagcaccg gaaattcaag cacacgcatg acaagacggc actgaaggag acccttggag   1740

cctaggggca tcggcaggag agtgtgtggg cagggttatt taatatggta tttgctgtat   1800

tgcccccatg gggtccttgg agtgataata ttgtttccct cgtccgtctg tctcgatgcc   1860

tgattcggac ggccaatggt gcttccccca cccctccacg tgtccgtcca cccttccatc   1920

agcgggtctc ctcccagcgg cctccggcgt cttgcccagc agctcaag                1968


<210>  10490
<211>  241
<212>  PRT
<213>  Homo sapiens

<400>  10490

Met Asn Arg Cys Trp Ala Leu Phe Leu Ser Leu Cys Cys Tyr Leu Arg 
1               5                   10                  15


Leu Val Ser Ala Glu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu Met 
            20                  25                  30


Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu Leu 
        35                  40                  45


His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn Met 
    50                  55                  60


Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly Arg 
65                  70                  75                  80


Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala Glu 
                85                  90                  95


Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile Asp 
            100                 105                 110


Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val Gln 
        115                 120                 125


Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro Thr 
    130                 135                 140


Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val Arg 
145                 150                 155                 160


Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His Leu 
                165                 170                 175


Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg Ser 
            180                 185                 190


Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg Val 
        195                 200                 205


Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His Arg 
    210                 215                 220


Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu Gly 
225                 230                 235                 240


Ala 



<210>  10491
<211>  1697
<212>  DNA
<213>  Homo sapiens

<400>  10491
cgaatcggac agtgtagaac cattctctac tgccttcctt ctgagaacag ccttgtggtc     60

agaagtggct gggatagcgg agggccaggg gacaacttct taacacgttc ctggaccctt    120

tgctctttgt agcctactga taactgcaaa ggggagcttg gaattatgtt agtcagtccc    180

tgtgaatggg ggagcttaaa ctaatggatg ccttaaaaag cacccattca gaattgagtt    240

cagggtgaca cccccagagc ctatccagct tgacagggga gacctgtggg taatgcacat    300

gaaataatct tatcactccc tcagatgacc cagccatggt tggtaattgc tgagtagcag    360

gaaggggtca gtgggaggtg ctgggcgctg aggtgaagta atgtgtatcc attccagggg    420

tcaccagtcg ttggcacacc aagaagctgc cccgcaagac ccaccgaggc ctgcgcaagg    480

tggcctgtat tggggcatgg catcctgctc gtgtagcctt ctctgtggca cgcgctgggc    540

agaaaggcta ccatcaccgc actgagatca acaagaagat ttataagatt ggccagggct    600

accttatcaa ggacggcaag ctgatcaaga acaatgcctc cactgactat gacctatctg    660

acaagagcat caaccctctg gtaagtaatg ggtgttctgc tctgtgaggc catcccaggc    720

ctcgtgcttt tggggatagg ctgcttccta ggggctgcta gcaggatcgt taactgaagc    780

caacacaaca cctagctgtg tcccttgtaa gtggcatgtt gtcatctgag tccactcgtc    840

ggggttggct ggtgagaagt ggggtctcag gctcagctgt tcagtgatga ggcctggaat    900

gtgcgctggg cacagcgccc gagacagact gcggaaccgt tccttgttgc cttccttctg    960

agaacagccc tgtggtcagg gagggcctga acctggaggg gtcatctgca cgacaatccc   1020

ctcctgggcc tgtgctgatc cgatgctcgt tttccagggt ggctttgtcc actatggtga   1080

agtgaccaat gactttgtca tgctgaaagg ctgtgtggtg ggaaccaaga agcgggtgct   1140

caccctccgc aaggtgaggc aggtcctgac ttgtcatggg ggggctcttg tagagggagg   1200

atccaaggcc acagacgctg gtggccctgt ggtgggagag gaaaggaagg agagggtgtt   1260

ggcagtcctt tcacactggc tttgaagtcc tgagatgagg aaattcccag tctggccttg   1320

ctgggctgtt tgctgctttg agtgtgtcct catctgccgg atggtggggg aggctgaatt   1380

gatcgtgtgg cttcccagat gcaggggcgc tgtgaacagt gctgaggaaa gcctggctcc   1440

tcgtaatcct aaatcccttc ccctcttggc ccatagtcct tgctggtgca gacgaagcgg   1500

cgggctctgg agaagattga ccttaagttc attgacacca cctccaagtt tggccatggc   1560

cgcttccaga ccatggagga gaagaaagca ttcatgggac cactgaagaa agaccgaatt   1620

gcaaaggaag aaggagctta atgccaggaa cagattttgc agttggtggg gtctcaataa   1680

aagttatttt ccactga                                                  1697


<210>  10492
<211>  103
<212>  PRT
<213>  Homo sapiens

<400>  10492

Met Arg Lys Phe Pro Val Trp Pro Cys Trp Ala Val Cys Cys Phe Glu 
1               5                   10                  15


Cys Val Leu Ile Cys Arg Met Val Gly Glu Ala Glu Leu Ile Val Trp 
            20                  25                  30


Leu Pro Arg Cys Arg Gly Ala Val Asn Ser Ala Glu Glu Ser Leu Ala 
        35                  40                  45


Pro Arg Asn Pro Lys Ser Leu Pro Leu Leu Ala His Ser Pro Cys Trp 
    50                  55                  60


Cys Arg Arg Ser Gly Gly Leu Trp Arg Arg Leu Thr Leu Ser Ser Leu 
65                  70                  75                  80


Thr Pro Pro Pro Ser Leu Ala Met Ala Ala Ser Arg Pro Trp Arg Arg 
                85                  90                  95


Arg Lys His Ser Trp Asp His 
            100


<210>  10493
<211>  1690
<212>  DNA
<213>  Homo sapiens

<400>  10493
ggtgaacaag aaggaggtgg tggaggctgt gaccattgta gagacaccac ccatggtggt     60

tgtgggcatt gtgggctacg tggaaacccc tcgaggcctc cggaccttca agactgtctt    120

tgctgagcac atcagtgatg aatgcaagag gcgtttctat aagaattggt aagggaggag    180

gccatgcagt ccctagcttg ggagcttggg agctggagag cagggagcag cgtgtgcatg    240

gtttctcagc tctgtagcag gcagggagct gctgtcttgg gtttagtttg cctctcgaac    300

agaaaaatac ctgggatcag acttggccag ccatctggtt tcagccggaa gctaacaccc    360

tcattctgag tccaggctag tgggtggtgg ctgaggaccc agttggttga ggagtccaac    420

tagaaaccag gagaggtagc agaataatta aacccctata ggggtggcaa gggcctctgg    480

ccctgggtgg aatgtcccat ttccttcatc actgagtggg cttccccagg gcagaaaggt    540

ttgtcccgga gcaagaattt tgtttgaatg cgtgtaactt aaattaacct tgtggacctc    600

tgctcagctc cgctcggctc tgcccgatga gctccatcca ggctccgctt gctggtggaa    660

aaggctcctt agaagccggc aatgagctcc atccccacgc ggtgccagtg tgccttccgc    720

tcacccctcg gaggggtgat gaaggcctgc acctggtccc ctccccaact ctgctctgct    780

cctgaaggca taaatctaag aagaaggcct ttaccaagta ctgcaagaaa tggcaggatg    840

aggatggcaa gaagcagctg gagaaggact tcagcagcat gaagaagtac tgccaagtca    900

tccgtgtcat tgcccacacc cagatgcgcc tgcttcctct gcgccagaag aaggcccacc    960

tgatggagat ccaggtgaac ggaggcactg tggccgagaa gctggactgg gcccgcgaga   1020

ggcttgagca gcaggtacct gtgaaccaag tgtttgggca ggatgagatg atcgacgtca   1080

tcggggtgac caagggcaaa ggctacaaag gggtcaccag tcgttggcac accaagaagc   1140

tgccccgcaa gacccaccga ggcctgcgca aggtggcctg tattggggca tggcatcctg   1200

ctcgtgtagc cttctctgtg gcacgcgctg ggcagaaagg ctaccatcac cgcactgaga   1260

tcaacaagaa gatttataag attggccagg gctaccttat caaggacggc aagctgatca   1320

agaacaatgc ctccactgac tatgacctat ctgacaagag catcaaccct ctgggtggct   1380

ttgtccacta tggtgaagtg accaatgact ttgtcatgct gaaaggctgt gtggtgggaa   1440

ccaagaagcg ggtgctcacc ctccgcaagt ccttgctggt gcagacgaag cggcgggctc   1500

tggagaagat tgaccttaag ttcattgaca ccacctccaa gtttggccat ggccgcttcc   1560

agaccatgga ggagaagaaa gcattcatgg gaccactgaa gaaagaccga attgcaaagg   1620

aagaaggagc ttaatgccag gaacagattt tgcagttggt ggggtctcaa taaaagttat   1680

tttccactga                                                          1690


<210>  10494
<211>  251
<212>  PRT
<213>  Homo sapiens

<400>  10494

Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His Thr Gln Met 
1               5                   10                  15


Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu Met Glu Ile Gln 
            20                  25                  30


Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp Trp Ala Arg Glu Arg 
        35                  40                  45


Leu Glu Gln Gln Val Pro Val Asn Gln Val Phe Gly Gln Asp Glu Met 
    50                  55                  60


Ile Asp Val Ile Gly Val Thr Lys Gly Lys Gly Tyr Lys Gly Val Thr 
65                  70                  75                  80


Ser Arg Trp His Thr Lys Lys Leu Pro Arg Lys Thr His Arg Gly Leu 
                85                  90                  95


Arg Lys Val Ala Cys Ile Gly Ala Trp His Pro Ala Arg Val Ala Phe 
            100                 105                 110


Ser Val Ala Arg Ala Gly Gln Lys Gly Tyr His His Arg Thr Glu Ile 
        115                 120                 125


Asn Lys Lys Ile Tyr Lys Ile Gly Gln Gly Tyr Leu Ile Lys Asp Gly 
    130                 135                 140


Lys Leu Ile Lys Asn Asn Ala Ser Thr Asp Tyr Asp Leu Ser Asp Lys 
145                 150                 155                 160


Ser Ile Asn Pro Leu Gly Gly Phe Val His Tyr Gly Glu Val Thr Asn 
                165                 170                 175


Asp Phe Val Met Leu Lys Gly Cys Val Val Gly Thr Lys Lys Arg Val 
            180                 185                 190


Leu Thr Leu Arg Lys Ser Leu Leu Val Gln Thr Lys Arg Arg Ala Leu 
        195                 200                 205


Glu Lys Ile Asp Leu Lys Phe Ile Asp Thr Thr Ser Lys Phe Gly His 
    210                 215                 220


Gly Arg Phe Gln Thr Met Glu Glu Lys Lys Ala Phe Met Gly Pro Leu 
225                 230                 235                 240


Lys Lys Asp Arg Ile Ala Lys Glu Glu Gly Ala 
                245                 250


<210>  10495
<211>  3157
<212>  DNA
<213>  Homo sapiens

<400>  10495
aggtgaacaa gaaggaggtg gtggaggctg tgaccattgt agagacacca cccatggtgg     60

ttgtgggcat tgtgggctac gtggaaaccc ctcgaggcct ccggaccttc aagactgtct    120

ttgctgagca catcagtgat gaatgcaaga ggcgtttcta taagaattgc tccgctcggc    180

tctgcccgat gagctccatc caggctccgc ttgctggtgg aaaaggctcc ttagaagccg    240

gcaatgagct ccatccccac gcggtgccag tgtgccttcc gctcacccct cggaggggtg    300

atgaaggcct gcacctggtc ccctccccaa ctctgctctg ctcctgaagg cataaatcta    360

agaagaaggc ctttaccaag tactgcaaga aatggcagga tgaggatggc aagaagcagc    420

tggagaagga cttcagcagc atgaagaagt actgccaagt catccgtgtc attgcccaca    480

cccagatgcg cctgcttcct ctgcgccaga agaaggccca cctgatggag atccaggtga    540

acggaggcac tgtggccgag aagctggact gggcccgcga gaggcttgag cagcaggtac    600

ctgtgaacca agtgtttggg caggatgaga tgatcgacgt catcggggtg accaagggca    660

aaggctacaa aggtgagctt tgcggtggct tgagttgctg tgcaaacctg ggggagaagt    720

ggtttcaggc ccagctgttc gttgatgagg ctcagagtga gcgctgggta cagcgcccga    780

atcggacagt gtagaaccat tctctactgc cttccttctg agaacagcct tgtggtcaga    840

agtggctggg atagcggagg gccaggggac aacttcttaa cacgttcctg gaccctttgc    900

tctttgtagc ctactgataa ctgcaaaggg gagcttggaa ttatgttagt cagtccctgt    960

gaatggggga gcttaaacta atggatgcct taaaaagcac ccattcagaa ttgagttcag   1020

ggtgacaccc ccagagccta tccagcttga caggggagac ctgtgggtaa tgcacatgaa   1080

ataatcttat cactccctca gatgacccag ccatggttgg taattgctga gtagcaggaa   1140

ggggtcagtg ggaggtgctg ggcgctgagg tgaagtaatg tgtatccatt ccaggggtca   1200

ccagtcgttg gcacaccaag aagctgcccc gcaagaccca ccgaggcctg cgcaaggtgg   1260

cctgtattgg ggcatggcat cctgctcgtg tagccttctc tgtggcacgc gctgggcaga   1320

aaggctacca tcaccgcact gagatcaaca agaaggtgag gttctgagag tggctccctg   1380

ggggtgggaa gaggcccccg tgatggggag tggggtttct gtgcctgtca gtgctgcttc   1440

actgactgta gcttatgcat cacgtggaca tcagtggctt gcttctcatg gtcagttctg   1500

gcccatcttg atgatttgta aggtgccatc ctgtagagtg gctgtggtgg ggctgactgg   1560

tgtggctggg gatactagtc ttattggtcc ctgatgccac caccaggggg gtgacaggcc   1620

tgtgttgtac agcaggatct ttagttttag cccagccgcc ttacagaaag gaacctggag   1680

ggccagccag ctttttgctc tgaccttggg atacgctgtg actgggactg aggcctcagc   1740

tgccttctag cgtgctttgc aggtcagcac actggcatgt ctgggttatt tgtccctaat   1800

gccccagcct tacacccttc ttgttcattc agatttataa gattggccag ggctacctta   1860

tcaaggacgg caagctgatc aagaacaatg cctccactga ctatgaccta tctgacaaga   1920

gcatcaaccc tctggtaagt aatgggtgtt ctgctctgtg aggccatccc aggcctcgtg   1980

cttttgggga taggctgctt cctaggggct gctagcagga tcgttaactg aagccaacac   2040

aacacctagc tgtgtccctt gtaagtggca tgttgtcatc tgagtccact cgtcggggtt   2100

ggctggtgag aagtggggtc tcaggctcag ctgttcagtg atgaggcctg gaatgtgcgc   2160

tgggcacagc gcccgagaca gactgcggaa ccgttccttg ttgccttcct tctgagaaca   2220

gccctgtggt cagggagggc ctgaacctgg aggggtcatc tgcacgacaa tcccctcctg   2280

ggcctgtgct gatccgatgc tcgttttcca gggtggcttt gtccactatg gtgaagtgac   2340

caatgacttt gtcatgctga aaggctgtgt ggtgggaacc aagaagcggg tgctcaccct   2400

ccgcaaggtg aggcaggtcc tgacttgtca tgggggggct cttgtagagg gaggatccaa   2460

ggccacagac gctggtggcc ctgtggtggg agaggaaagg aaggagaggg tgttggcagt   2520

cctttcacac tggctttgaa gtcctgagat gaggaaattc ccagtctggc cttgctgggc   2580

tgtttgctgc tttgagtgtg tcctcatctg ccggatggtg ggggaggctg aattgatcgt   2640

gtggcttccc agatgcaggg gcgctgtgaa cagtgctgag gaaagcctgg ctcctcgtaa   2700

tcctaaatcc cttcccctct tggcccatag tccttgctgg tgcagacgaa gcggcgggct   2760

ctggagaaga ttgaccttaa gttcattgac accacctcca agtttggcca tggccgcttc   2820

cagaccatgg aggagaagaa agcattcatg gtgagcacct ctgcctgccc ccctcgctgg   2880

gtgtggtggc ttgggcagcc gcctgccttt ggctccagcc ggggtagggg tggtcttgat   2940

gccttaggcc tctcttgtgg ctgtggagac tggcccagag tcttggtctc ctctagagtg   3000

ggcatctgct gtcacctgtc atcttctacc tctgaccact gcctctctcc ccacagggac   3060

cactgaagaa agaccgaatt gcaaaggaag aaggagctta atgccaggaa cagattttgc   3120

agttggtggg gtctcaataa aagttatttt ccactga                            3157


<210>  10496
<211>  117
<212>  PRT
<213>  Homo sapiens

<400>  10496

Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His Thr Gln Met 
1               5                   10                  15


Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu Met Glu Ile Gln 
            20                  25                  30


Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp Trp Ala Arg Glu Arg 
        35                  40                  45


Leu Glu Gln Gln Val Pro Val Asn Gln Val Phe Gly Gln Asp Glu Met 
    50                  55                  60


Ile Asp Val Ile Gly Val Thr Lys Gly Lys Gly Tyr Lys Gly Glu Leu 
65                  70                  75                  80


Cys Gly Gly Leu Ser Cys Cys Ala Asn Leu Gly Glu Lys Trp Phe Gln 
                85                  90                  95


Ala Gln Leu Phe Val Asp Glu Ala Gln Ser Glu Arg Trp Val Gln Arg 
            100                 105                 110


Pro Asn Arg Thr Val 
        115


<210>  10497
<211>  2158
<212>  DNA
<213>  Homo sapiens

<400>  10497
aggtgaacaa gaaggaggtg gtggaggctg tgaccattgt agagacacca cccatggtgg     60

ttgtgggcat tgtgggctac gtggaaaccc ctcgaggcct ccggaccttc aagactgtct    120

ttgctgagca catcagtgat gaatgcaaga ggcgtttcta taagaattgc tccgctcggc    180

tctgcccgat gagctccatc caggctccgc ttgctggtgg aaaaggctcc ttagaagccg    240

gcaatgagct ccatccccac gcggtgccag tgtgccttcc gctcacccct cggaggggtg    300

atgaaggcct gcacctggtc ccctccccaa ctctgctctg ctcctgaagg cataaatcta    360

agaagaaggc ctttaccaag tactgcaaga aatggcagga tgaggatggc aagaagcagc    420

tggagaagga cttcagcagc atgaagaagt actgccaagt catccgtgtc attgcccaca    480

cccagatgcg cctgcttcct ctgcgccaga agaaggccca cctgatggag atccaggtga    540

acggaggcac tgtggccgag aagctggact gggcccgcga gaggcttgag cagcaggtac    600

ctgtgaacca agtgtttggg caggatgaga tgatcgacgt catcggggtg accaagggca    660

aaggctacaa aggggtcacc agtcgttggc acaccaagaa gctgccccgc aagacccacc    720

gaggcctgcg caaggtggcc tgtattgggg catggcatcc tgctcgtgta gccttctctg    780

tggcacgcgc tgggcagaaa ggctaccatc accgcactga gatcaacaag aagatttata    840

agattggcca gggctacctt atcaaggacg gcaagctgat caagaacaat gcctccactg    900

actatgacct atctgacaag agcatcaacc ctctggtaag taatgggtgt tctgctctgt    960

gaggccatcc caggcctcgt gcttttgggg ataggctgct tcctaggggc tgctagcagg   1020

atcgttaact gaagccaaca caacacctag ctgtgtccct tgtaagtggc atgttgtcat   1080

ctgagtccac tcgtcggggt tggctggtga gaagtggggt ctcaggctca gctgttcagt   1140

gatgaggcct ggaatgtgcg ctgggcacag cgcccgagac agactgcgga accgttcctt   1200

gttgccttcc ttctgagaac agccctgtgg tcagggaggg cctgaacctg gaggggtcat   1260

ctgcacgaca atcccctcct gggcctgtgc tgatccgatg ctcgttttcc agggtggctt   1320

tgtccactat ggtgaagtga ccaatgactt tgtcatgctg aaaggctgtg tggtgggaac   1380

caagaagcgg gtgctcaccc tccgcaaggt gaggcaggtc ctgacttgtc atgggggggc   1440

tcttgtagag ggaggatcca aggccacaga cgctggtggc cctgtggtgg gagaggaaag   1500

gaaggagagg gtgttggcag tcctttcaca ctggctttga agtcctgaga tgaggaaatt   1560

cccagtctgg ccttgctggg ctgtttgctg ctttgagtgt gtcctcatct gccggatggt   1620

gggggaggct gaattgatcg tgtggcttcc cagatgcagg ggcgctgtga acagtgctga   1680

ggaaagcctg gctcctcgta atcctaaatc ccttcccctc ttggcccata gtccttgctg   1740

gtgcagacga agcggcgggc tctggagaag attgacctta agttcattga caccacctcc   1800

aagtttggcc atggccgctt ccagaccatg gaggagaaga aagcattcat ggtgagcacc   1860

tctgcctgcc cccctcgctg ggtgtggtgg cttgggcagc cgcctgcctt tggctccagc   1920

cggggtaggg gtggtcttga tgccttaggc ctctcttgtg gctgtggaga ctggcccaga   1980

gtcttggtct cctctagagt gggcatctgc tgtcacctgt catcttctac ctctgaccac   2040

tgcctctctc cccacaggga ccactgaaga aagaccgaat tgcaaaggaa gaaggagctt   2100

aatgccagga acagattttg cagttggtgg ggtctcaata aaagttattt tccactga     2158


<210>  10498
<211>  173
<212>  PRT
<213>  Homo sapiens

<400>  10498

Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His Thr Gln Met 
1               5                   10                  15


Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu Met Glu Ile Gln 
            20                  25                  30


Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp Trp Ala Arg Glu Arg 
        35                  40                  45


Leu Glu Gln Gln Val Pro Val Asn Gln Val Phe Gly Gln Asp Glu Met 
    50                  55                  60


Ile Asp Val Ile Gly Val Thr Lys Gly Lys Gly Tyr Lys Gly Val Thr 
65                  70                  75                  80


Ser Arg Trp His Thr Lys Lys Leu Pro Arg Lys Thr His Arg Gly Leu 
                85                  90                  95


Arg Lys Val Ala Cys Ile Gly Ala Trp His Pro Ala Arg Val Ala Phe 
            100                 105                 110


Ser Val Ala Arg Ala Gly Gln Lys Gly Tyr His His Arg Thr Glu Ile 
        115                 120                 125


Asn Lys Lys Ile Tyr Lys Ile Gly Gln Gly Tyr Leu Ile Lys Asp Gly 
    130                 135                 140


Lys Leu Ile Lys Asn Asn Ala Ser Thr Asp Tyr Asp Leu Ser Asp Lys 
145                 150                 155                 160


Ser Ile Asn Pro Leu Val Ser Asn Gly Cys Ser Ala Leu 
                165                 170


<210>  10499
<211>  1537
<212>  DNA
<213>  Homo sapiens

<400>  10499
ggtgaacaag aaggaggtgg tggaggctgt gaccattgta gagacaccac ccatggtggt     60

tgtgggcatt gtgggctacg tggaaacccc tcgaggcctc cggaccttca agactgtctt    120

tgctgagcac atcagtgatg aatgcaagag gcgtttctat aagaattggt aagggaggag    180

gccatgcagt ccctagcttg ggagcttggg agctggagag cagggagcag cgtgtgcatg    240

gtttctcagc tctgtagcag gcagggagct gctgtcttgg gtttagtttg cctctcgaac    300

agaaaaatac ctgggatcag acttggccag ccatctggtt tcagccggaa gctaacaccc    360

tcattctgag tccaggctag tgggtggtgg ctgaggaccc agttggttga ggagtccaac    420

tagaaaccag gagaggtagc agaataatta aacccctata ggggtggcaa gggcctctgg    480

ccctgggtgg aatgtcccat ttccttcatc actgagtggg cttccccagg gcagaaaggt    540

ttgtcccgga gcaagaattt tgtttgaatg cgtgtaactt aaattaacct tgtggacctc    600

tgctcagctc cgctcggctc tgcccgatga gctccatcca ggctccgctt gctggtggaa    660

aaggctcctt agaagccggc aatgagctcc atccccacgc ggtgccagtg tgccttccgc    720

tcacccctcg gaggggtgat gaaggcctgc acctggtccc ctccccaact ctgctctgct    780

cctgaaggca taaatctaag aagaaggcct ttaccaagta ctgcaagaaa tggcaggatg    840

aggatggcaa gaagcagctg gagaaggact tcagcagcat gaagaagtac tgccaagtca    900

tccgtgtcat tgcccacacc cagatgcgcc tgcttcctct gcgccagaag aaggcccacc    960

tgatggagat ccaggtgaac ggaggcactg tggccgagaa gctggactgg gcccgcgaga   1020

ggcttgagca gcaggtacct gtgaaccaag tgtttgggca ggatgagatg atcgacgtca   1080

tcggggtgac caagggcaaa ggctacaaag gggtcaccag tcgttggcac accaagaagc   1140

tgccccgcaa gacccaccga ggcctgcgca aggtggcctg tattggggca tggcatcctg   1200

ctcgtgtagc cttctctgtg gcacgcgctg ggcagaaagg ctaccatcac cgcactgaga   1260

tcaacaagaa gatttataag attggccagg gctaccttat caaggacggc aagctgatca   1320

agaacaatgc ctccactgac tatgacctat ctgacaagag catcaaccct ctgggtggct   1380

ttgtccacta tggtgaagtg accaatgact ttgtcatgct gaaaggctgt gtggtgggaa   1440

ccaagaagcg ggtgctcacc ctcctcctga gatgagacga agcggcgggc tctggagaag   1500

attgacctta agttcattga caccacctcc aagtttg                            1537


<210>  10500
<211>  198
<212>  PRT
<213>  Homo sapiens

<400>  10500

Met Lys Lys Tyr Cys Gln Val Ile Arg Val Ile Ala His Thr Gln Met 
1               5                   10                  15


Arg Leu Leu Pro Leu Arg Gln Lys Lys Ala His Leu Met Glu Ile Gln 
            20                  25                  30


Val Asn Gly Gly Thr Val Ala Glu Lys Leu Asp Trp Ala Arg Glu Arg 
        35                  40                  45


Leu Glu Gln Gln Val Pro Val Asn Gln Val Phe Gly Gln Asp Glu Met 
    50                  55                  60


Ile Asp Val Ile Gly Val Thr Lys Gly Lys Gly Tyr Lys Gly Val Thr 
65                  70                  75                  80


Ser Arg Trp His Thr Lys Lys Leu Pro Arg Lys Thr His Arg Gly Leu 
                85                  90                  95


Arg Lys Val Ala Cys Ile Gly Ala Trp His Pro Ala Arg Val Ala Phe 
            100                 105                 110


Ser Val Ala Arg Ala Gly Gln Lys Gly Tyr His His Arg Thr Glu Ile 
        115                 120                 125


Asn Lys Lys Ile Tyr Lys Ile Gly Gln Gly Tyr Leu Ile Lys Asp Gly 
    130                 135                 140


Lys Leu Ile Lys Asn Asn Ala Ser Thr Asp Tyr Asp Leu Ser Asp Lys 
145                 150                 155                 160


Ser Ile Asn Pro Leu Gly Gly Phe Val His Tyr Gly Glu Val Thr Asn 
                165                 170                 175


Asp Phe Val Met Leu Lys Gly Cys Val Val Gly Thr Lys Lys Arg Val 
            180                 185                 190


Leu Thr Leu Leu Leu Arg 
        195


<210>  10501
<211>  1155
<212>  DNA
<213>  Homo sapiens

<400>  10501
ctctaccggc gggatttgat ggcgtgatgg tatgtgttgt aatggcggcc gtttcattgt     60

caccggcgtc ggcacggctg aatccgcgac gcatcgccgc catcccgtct tggccggcgc    120

cgggggtttg ctttaggggc acgggcgacc cagcggggac ttcagtctgg cctattttct    180

ggaaagtcga gaggcttgtg aagagcttcc ctaaggatga cccgtccaag ccggtgaaca    240

agaaggaggt ggtggaggct gtgaccattg tagagacacc acccatggtg gttgtgggca    300

ttgtgggcta cgtggaaacc cctcgaggcc tccggacctt caagactgtc tttgctgagc    360

acatcagtga tgaatgcaag aggcgtttct ataagaattg gtaagggagg aggccatgca    420

gtccctagct tgggagcttg ggagctggag agcagggagc agcgtgtgca tggtttctca    480

gctctgtagc aggcagggag ctgctgtctt gggtttagtt tgcctctcga acagaaaaat    540

acctgggatc agacttggcc agccatctgg tttcagccgg aagctaacac cctcattctg    600

agtccaggct agtgggtggt ggctgaggac ccagttggtt gaggagtcca actagaaacc    660

aggagaggta gcagaataat taaaccccta taggggtggc aagggcctct ggccctgggt    720

ggaatgtccc atttccttca tcactgagtg ggcttcccca gggcagaaag gtttgtcccg    780

gagcaagaat tttgtttgaa tgcgtgtaac ttaaattaac cttgtggacc tctgctcagc    840

tccgctcggc tctgcccgat gagctccatc caggctccgc ttgctggtgg aaaaggctcc    900

ttagaagccg gcaatgagct ccatccccac gcggtgccag tgtgccttcc gctcacccct    960

cggaggggtg atgaaggcct gcacctggtc ccctccccaa ctctgctctg ctcctgaagg   1020

cataaatcta agaagaaggc ctttaccaag tactgcaaga aatggcagga tgaggatggc   1080

aagaagcagc tggagaagga cttcagcagc atgaagaagt actgccaagt catccgtgtc   1140

attgcccaca cccag                                                    1155


<210>  10502
<211>  125
<212>  PRT
<213>  Homo sapiens

<400>  10502

Met Val Cys Val Val Met Ala Ala Val Ser Leu Ser Pro Ala Ser Ala 
1               5                   10                  15


Arg Leu Asn Pro Arg Arg Ile Ala Ala Ile Pro Ser Trp Pro Ala Pro 
            20                  25                  30


Gly Val Cys Phe Arg Gly Thr Gly Asp Pro Ala Gly Thr Ser Val Trp 
        35                  40                  45


Pro Ile Phe Trp Lys Val Glu Arg Leu Val Lys Ser Phe Pro Lys Asp 
    50                  55                  60


Asp Pro Ser Lys Pro Val Asn Lys Lys Glu Val Val Glu Ala Val Thr 
65                  70                  75                  80


Ile Val Glu Thr Pro Pro Met Val Val Val Gly Ile Val Gly Tyr Val 
                85                  90                  95


Glu Thr Pro Arg Gly Leu Arg Thr Phe Lys Thr Val Phe Ala Glu His 
            100                 105                 110


Ile Ser Asp Glu Cys Lys Arg Arg Phe Tyr Lys Asn Trp 
        115                 120                 125


<210>  10503
<211>  1708
<212>  DNA
<213>  Homo sapiens

<400>  10503
acccagaccc agaaggcgcc accatggcgg cgcccccgca gcccgtcacc cacctcatct     60

ttgacatgga cggacttctt ctggatactg aacggctgta ttcagtggtg tttcaagaaa    120

tatgtaatcg ctatgacaag aaatacagct gggatgtaaa gtccctggtt atgggtaaga    180

aggcattaga ggcggccctg gcagctggga tgcaggtggt catggttcct gacggaaact    240

tgagccgaga tctgacaaca aaggccaccc tggtgctgaa ttccctgcag gacttccagc    300

ccgagctgtt tggtttgccc tcctatgagt gagagggagg gcctcagtct tccgccccca    360

gcccactctc atggtccaca ctgctggggg aaagggaaag gaaatcagca actcttcaat    420

cccaacctgc gctgtgattt tagcctcctg agattggagt ttccatccca tgttggtttg    480

tcccagtcta acgtgttgat aaaatgtgac ttgacggttg agacaaaaaa tacagtagag    540

acagaaacga agcccagaac aaagatgaaa cttgaattac catctcagaa gtcaagctga    600

tggagtatgt gataaagtga atgtacatgt atatacacac acacctccat atatacatgt    660

gtgtatcagt ttggtaatat gcaggtaggc attacatgca tatgtatgta gacatatgca    720

tgcatgtata tgtaaaatat atacttttcc aagacaaaat ggaacatcac ttctctcttc    780

tagtttttct gaacactggc tgggaaatgt aaactgtgta tgcatataag tatatgcttt    840

atgtatgcat atgtatgtag atatgtttat atctatcgtc tgcatcactc tcctcagtgt    900

tgatgtcaac atgcaatgac aactgataaa gcgagatggt agttctgcct ggtttgcagt    960

ctgagtggga aagtcctgtt tttgatgagc actccttgtt agctaacatt taaattcttt   1020

ttgtgacctc agaatgtctc tggatctttc ctcattgact gactctgtgc cacgtcatcc   1080

atagtttatt gttagtatga acacaactgt aacatttacc tggtatctac atccttacct   1140

gcattggaaa atgtttgcta cctcacaaca accatttgcc tcctttaaga acactgatgg   1200

gctgcacttt ttggatagaa atagaatttg atttcagaat gtatgcttgg tgagtctcag   1260

tgcccaggaa cacttttgga ataatttatc agacattgaa cttctgtgat taatcgcttt   1320

tatagattta ctcagtcttt aaaattcgtc tctgatttgc cagagaaaaa cggtggtagc   1380

catggaaatc gggagtgaag gagcactgct tcattgtggc tcagcccttc ctaggggcct   1440

ctgccctttg atgtccttga gctactcttc agctctggaa gttgtggaca aaccgtagga   1500

atgtatgtgt gcgtgtggtg gagtgattgt ctgtgaatga caggccctgg ctattgattg   1560

atgttgcatc aatttagcaa attcatttcc tcattcttga tggcctgaat atatgtctgc   1620

acttttaatg ctcctcttaa ccagttgtaa catcttacca tttccctaac aaattgaatt   1680

agtttaataa aatcttttga cacatgtt                                      1708


<210>  10504
<211>  102
<212>  PRT
<213>  Homo sapiens

<400>  10504

Met Ala Ala Pro Pro Gln Pro Val Thr His Leu Ile Phe Asp Met Asp 
1               5                   10                  15


Gly Leu Leu Leu Asp Thr Glu Arg Leu Tyr Ser Val Val Phe Gln Glu 
            20                  25                  30


Ile Cys Asn Arg Tyr Asp Lys Lys Tyr Ser Trp Asp Val Lys Ser Leu 
        35                  40                  45


Val Met Gly Lys Lys Ala Leu Glu Ala Ala Leu Ala Ala Gly Met Gln 
    50                  55                  60


Val Val Met Val Pro Asp Gly Asn Leu Ser Arg Asp Leu Thr Thr Lys 
65                  70                  75                  80


Ala Thr Leu Val Leu Asn Ser Leu Gln Asp Phe Gln Pro Glu Leu Phe 
                85                  90                  95


Gly Leu Pro Ser Tyr Glu 
            100


<210>  10505
<211>  2177
<212>  DNA
<213>  Homo sapiens

<400>  10505
cgcgcacttc ctcctcgccc ccacccagac ccagaaggcg ccaccatggc ggcgcccccg     60

cagcccgtca cccacctcat ctttgacatg gacggacttc ttctgggtta tacaggaagc    120

atagtggcag ctgcttcggg ggagtcctca agaggcttac aatcacggtg gacggatact    180

gaacggctgt attcagtggt gtttcaagaa atatgtaatc gctatgacaa gaaatacagc    240

tgggatgtaa agtccctggt tatgggtaag aaggcattag aggcggcaca gattataata    300

gacgtcttgc agctcccgat gtccaaagag gagctggtgg aagaaagcca aacgaagtta    360

aaggaagtgt tccccacggc tgcgctcatg ccaggggcgg agaaactcat catccacctg    420

cggaaacatg gcatcccctt tgcactggcc accagctcgg ggtccgcgtc gttcgatatg    480

aagacaagcc gccacaagga gttcttcagc ttgttttccc acattgtgct gggagatgac    540

cccgaagtgc agcatggcaa gccagacccg gacatcttcc tagcttgtgc caagaggttc    600

tctccccctc ctgctatgga gaagtgcctt gtctttgaag atgctcccaa tggggtggag    660

gcggccctgg cagctgggat gcaggtggtc atggttcctg acggaaactt gagccgagat    720

ctgacaacaa aggccaccct ggtgctgaat tccctgcagg acttccagcc cgagctgttt    780

ggtttgccct cctatgagtg agagggaggg cctcagtctt ccgcccccag cccactctca    840

tggtccacac tgctggggga aagggaaagg aaatcagcaa ctcttcaatc ccaacctgcg    900

ctgtgatttt agcctcctga gattggagtt tccatcccat gttggtttgt cccagtctaa    960

cgtgttgata aaatgtgact tgacggttga gacaaaaaat acagtagaga cagaaacgaa   1020

gcccagaaca aagatgaaac ttgaattacc atctcagaag tcaagctgat ggagtatgtg   1080

ataaagtgaa tgtacatgta tatacacaca cacctccata tatacatgtg tgtatcagtt   1140

tggtaatatg caggtaggca ttacatgcat atgtatgtag acatatgcat gcatgtatat   1200

gtaaaatata tacttttcca agacaaaatg gaacatcact tctctcttct agtttttctg   1260

aacactggct gggaaatgta aactgtgtat gcatataagt atatgcttta tgtatgcata   1320

tgtatgtaga tatgtttata tctatcgtct gcatcactct cctcagtgtt gatgtcaaca   1380

tgcaatgaca actgataaag cgagatggta gttctgcctg gtttgcagtc tgagtgggaa   1440

agtcctgttt ttgatgagca ctccttgtta gctaacattt aaattctttt tgtgacctca   1500

gaatgtctct ggatctttcc tcattgactg actctgtgcc acgtcatcca tagtttattg   1560

ttagtatgaa cacaactgta acatttacct ggtatctaca tccttacctg cattggaaaa   1620

tgtttgctac ctcacaacaa ccatttgcct cctttaagaa cactgatggg ctgcactttt   1680

tggatagaaa tagaatttga tttcagaatg tatgcttggt gagtctcagt gcccaggaac   1740

acttttggaa taatttatca gacattgaac ttctgtgatt aatcgctttt atagatttac   1800

tcagtcttta aaattcgtct ctgatttgcc agagaaaaac ggtggtagcc atggaaatcg   1860

ggagtgaagg agcactgctt cattgtggct cagcccttcc taggggcctc tgccctttga   1920

tgtccttgag ctactcttca gctctggaag ttgtggacaa accgtaggaa tgtatgtgtg   1980

cgtgtggtgg agtgattgtc tgtgaatgac aggccctggc tattgattga tgttgcatca   2040

atttagcaaa ttcatttcct cattcttgat ggcctgaata tatgtctgca cttttaatgc   2100

tcctcttaac cagttgtaac atcttaccat ttccctaaca aattgaatta gtttaataaa   2160

atcttttgac acatgtt                                                  2177


<210>  10506
<211>  251
<212>  PRT
<213>  Homo sapiens

<400>  10506

Met Ala Ala Pro Pro Gln Pro Val Thr His Leu Ile Phe Asp Met Asp 
1               5                   10                  15


Gly Leu Leu Leu Gly Tyr Thr Gly Ser Ile Val Ala Ala Ala Ser Gly 
            20                  25                  30


Glu Ser Ser Arg Gly Leu Gln Ser Arg Trp Thr Asp Thr Glu Arg Leu 
        35                  40                  45


Tyr Ser Val Val Phe Gln Glu Ile Cys Asn Arg Tyr Asp Lys Lys Tyr 
    50                  55                  60


Ser Trp Asp Val Lys Ser Leu Val Met Gly Lys Lys Ala Leu Glu Ala 
65                  70                  75                  80


Ala Gln Ile Ile Ile Asp Val Leu Gln Leu Pro Met Ser Lys Glu Glu 
                85                  90                  95


Leu Val Glu Glu Ser Gln Thr Lys Leu Lys Glu Val Phe Pro Thr Ala 
            100                 105                 110


Ala Leu Met Pro Gly Ala Glu Lys Leu Ile Ile His Leu Arg Lys His 
        115                 120                 125


Gly Ile Pro Phe Ala Leu Ala Thr Ser Ser Gly Ser Ala Ser Phe Asp 
    130                 135                 140


Met Lys Thr Ser Arg His Lys Glu Phe Phe Ser Leu Phe Ser His Ile 
145                 150                 155                 160


Val Leu Gly Asp Asp Pro Glu Val Gln His Gly Lys Pro Asp Pro Asp 
                165                 170                 175


Ile Phe Leu Ala Cys Ala Lys Arg Phe Ser Pro Pro Pro Ala Met Glu 
            180                 185                 190


Lys Cys Leu Val Phe Glu Asp Ala Pro Asn Gly Val Glu Ala Ala Leu 
        195                 200                 205


Ala Ala Gly Met Gln Val Val Met Val Pro Asp Gly Asn Leu Ser Arg 
    210                 215                 220


Asp Leu Thr Thr Lys Ala Thr Leu Val Leu Asn Ser Leu Gln Asp Phe 
225                 230                 235                 240


Gln Pro Glu Leu Phe Gly Leu Pro Ser Tyr Glu 
                245                 250


<210>  10507
<211>  2132
<212>  DNA
<213>  Homo sapiens

<400>  10507
gcgtgcgcgg ggcgggcggg tgcgcgcgca cttcctcctc gcccccaccc agacccagaa     60

ggcgccacca tggcggcgcc cccgcagccc gtcacccacc tcatctttga catggacgga    120

cttcttctgg atactgaacg gctgtattca gtggtgtttc aagaaatatg taatcgctat    180

gacaagaaat acagctggga tgtaaagtcc ctggttatgg gtaagaaggc attagaggcg    240

gcacagatta taatagacgt cttgcagctc ccgatgtcca aagaggagct ggtggaagaa    300

agccaaacga agttaaagga agtgttcccc acggctgcgc tcatgccagg ggcggagaaa    360

ctcatcatcc acctgcggaa acatggcatc ccctttgcac tggccaccag ctcggggtcc    420

gcgtcgttcg atatgaagac aagccgccac aaggagttct tcagcttgtt ttcccacatt    480

gtgctgggag atgaccccga agtgcagcat ggcaagccag acccggacat cttcctagct    540

tgtgccaaga ggttctctcc ccctcctgct atggagaagt gccttgtctt tgaagatgct    600

cccaatgggg tggaggcggc cctggcagct gggatgcagg tggtcatggt tcctgacgga    660

aacttgagcc gagatctgac aacaaaggcc accctggtgc tgaattccct gcaggacttc    720

cagcccgagc tgtttggttt gccctcctat gagtgagagg gagggcctca gtcttccgcc    780

cccagcccac tctcatggtc cacactgctg ggggaaaggg aaaggaaatc agcaactctt    840

caatcccaac ctgcgctgtg attttagcct cctgagattg gagtttccat cccatgttgg    900

tttgtcccag tctaacgtgt tgataaaatg tgacttgacg gttgagacaa aaaatacagt    960

agagacagaa acgaagccca gaacaaagat gaaacttgaa ttaccatctc agaagtcaag   1020

ctgatggagt atgtgataaa gtgaatgtac atgtatatac acacacacct ccatatatac   1080

atgtgtgtat cagtttggta atatgcaggt aggcattaca tgcatatgta tgtagacata   1140

tgcatgcatg tatatgtaaa atatatactt ttccaagaca aaatggaaca tcacttctct   1200

cttctagttt ttctgaacac tggctgggaa atgtaaactg tgtatgcata taagtatatg   1260

ctttatgtat gcatatgtat gtagatatgt ttatatctat cgtctgcatc actctcctca   1320

gtgttgatgt caacatgcaa tgacaactga taaagcgaga tggtagttct gcctggtttg   1380

cagtctgagt gggaaagtcc tgtttttgat gagcactcct tgttagctaa catttaaatt   1440

ctttttgtga cctcagaatg tctctggatc tttcctcatt gactgactct gtgccacgtc   1500

atccatagtt tattgttagt atgaacacaa ctgtaacatt tacctggtat ctacatcctt   1560

acctgcattg gaaaatgttt gctacctcac aacaaccatt tgcctccttt aagaacactg   1620

atgggctgca ctttttggat agaaatagaa tttgatttca gaatgtatgc ttggtgagtc   1680

tcagtgccca ggaacacttt tggaataatt tatcagacat tgaacttctg tgattaatcg   1740

cttttataga tttactcagt ctttaaaatt cgtctctgat ttgccagaga aaaacggtgg   1800

tagccatgga aatcgggagt gaaggagcac tgcttcattg tggctcagcc cttcctaggg   1860

gcctctgccc tttgatgtcc ttgagctact cttcagctct ggaagttgtg gacaaaccgt   1920

aggaatgtat gtgtgcgtgt ggtggagtga ttgtctgtga atgacaggcc ctggctattg   1980

attgatgttg catcaattta gcaaattcat ttcctcattc ttgatggcct gaatatatgt   2040

ctgcactttt aatgctcctc ttaaccagtt gtaacatctt accatttccc taacaaattg   2100

aattagttta ataaaatctt ttgacacatg tt                                 2132


<210>  10508
<211>  228
<212>  PRT
<213>  Homo sapiens

<400>  10508

Met Ala Ala Pro Pro Gln Pro Val Thr His Leu Ile Phe Asp Met Asp 
1               5                   10                  15


Gly Leu Leu Leu Asp Thr Glu Arg Leu Tyr Ser Val Val Phe Gln Glu 
            20                  25                  30


Ile Cys Asn Arg Tyr Asp Lys Lys Tyr Ser Trp Asp Val Lys Ser Leu 
        35                  40                  45


Val Met Gly Lys Lys Ala Leu Glu Ala Ala Gln Ile Ile Ile Asp Val 
    50                  55                  60


Leu Gln Leu Pro Met Ser Lys Glu Glu Leu Val Glu Glu Ser Gln Thr 
65                  70                  75                  80


Lys Leu Lys Glu Val Phe Pro Thr Ala Ala Leu Met Pro Gly Ala Glu 
                85                  90                  95


Lys Leu Ile Ile His Leu Arg Lys His Gly Ile Pro Phe Ala Leu Ala 
            100                 105                 110


Thr Ser Ser Gly Ser Ala Ser Phe Asp Met Lys Thr Ser Arg His Lys 
        115                 120                 125


Glu Phe Phe Ser Leu Phe Ser His Ile Val Leu Gly Asp Asp Pro Glu 
    130                 135                 140


Val Gln His Gly Lys Pro Asp Pro Asp Ile Phe Leu Ala Cys Ala Lys 
145                 150                 155                 160


Arg Phe Ser Pro Pro Pro Ala Met Glu Lys Cys Leu Val Phe Glu Asp 
                165                 170                 175


Ala Pro Asn Gly Val Glu Ala Ala Leu Ala Ala Gly Met Gln Val Val 
            180                 185                 190


Met Val Pro Asp Gly Asn Leu Ser Arg Asp Leu Thr Thr Lys Ala Thr 
        195                 200                 205


Leu Val Leu Asn Ser Leu Gln Asp Phe Gln Pro Glu Leu Phe Gly Leu 
    210                 215                 220


Pro Ser Tyr Glu 
225


<210>  10509
<211>  4068
<212>  DNA
<213>  Homo sapiens

<400>  10509
agcgggcgcg ggcgctggca gagcgcggcg cggggccggc ggcgaaggtc cggggtggaa     60

tcgacgtcgc tgcggctgcc gacgacccac acccggccgg ccgcctccgc agacccacct    120

tggccgcgcg gcagggggcg cgcagagccc cgagggagcg agtccccgcg cgtggcagct    180

cggcggcttc tcccttcggg aggtccggct cccggctctc cggacccgcc tggcgtcctc    240

gcctgcggcg gggcggacga cagcggcgcc caggaatggc ttcggcgggc agcggcatgg    300

aggaggtgcg cgtgtcggtg ctgaccccct tgaagctggt cgggctggtg tgcatcttcc    360

tggcgctgtg tctggacctg ggggcggtgc tgagcccggc ctgggtcaca gctgaccacc    420

agtactacct gtcgttgtgg gagtcctgcc ggaaacccgc cagcttggac atctggcact    480

gcgagtccac gctcagcagc gattggcaga ttgctactct ggctttactc ctgggcggcg    540

ctgccatcat tctcattgca ttcctggtgg gtttgatttc tatctgcgtg ggatctcgaa    600

ggcgtttcta tagacctgtt gcggtcatgc tttttgcagc agttgtttta caggtttgca    660

gcctggtcct ttacccaatc aagttcattg aaactgtgag cttgaaaatt taccatgagt    720

tcaactgggg ttatggcctg gcctggggtg caactatatt ttcgtttggg ggtgccatcc    780

tttattgcct gaaccctaag aactatgaag actactacta gaaccaatag tctcaaagta    840

aaaacaacca ccaccatcca acaaaaggat tacgtctgca tcttttctaa cttactattt    900

tctaaaacac ttgtggagca tcaagcagtt tgctcagttg atttaatctt ttttgccttt    960

tggctgtcaa catcataacc agcttttaca tccattttag aaatctgcac aaattaagag   1020

agctgattag acataggcaa atgctgcaaa cttccaatat gttcatatcg tttttcttga   1080

caaatgaagg gtctatatga cagcaaccat tgtgagaaac tagttggaat gagatttgcc   1140

tcaatctcct attgcctgca ggggagcagt tggcataagc aacatttaga agttcctttg   1200

cgctgacaag gattccactg ttagagccct taccgcctgc ttatcctacc caatgactac   1260

attggctgtt ggttatttgc ttgagtgagc ccttgaaaaa tgaactgccc ttcagcatct   1320

aatgggagtt gtgaatgtaa ctggttaatg atacacattc caccttcagg aacactcttt   1380

ttaatgggag gttatgcttt ggcaatcagc gtctccctgg gaagagagtc aagacttgga   1440

gacatgtgct tctcattatg tggttagaaa ttggtgcctc agccctatct agactgggga   1500

aaaattgagg atctctgttt ttcctggggc aaacagaaag aaatctgcat gagttgcttt   1560

tgtacccttt aaatcatttg ccaaacattg cagcaaacaa gtgtgcgtat gtaacaagct   1620

tcactgtttt tatagaaggt gaaccattag tataaatggt aataagttgt tccctaaccc   1680

tccacataca tttgcctatc acacgtaaaa ttaatattta ctctagtgaa gtggtttgag   1740

cactaacctt gtacacattg ttaagaggct tagattggta ttcatactta tttaccatac   1800

aaaagtatgg taccttaaag cttttgctct atgttcttta ctgtttcact ggaaagtgtc   1860

aatagagttg cctaagaata aaaattgaaa tggtgttaat ctgaaaatta atgattctct   1920

gtaagcactg tagttgaaaa gagagtagca attaggatga tcattttgtg taaaattcat   1980

taaaatagaa ggctgctatt ttttgcaagt attttaaatg tcttcatttt tttaagaaag   2040

gaatagcgat agatttatat aaatatctaa atgtctcagt agaggagtag aattcatctg   2100

gttatcacct ggtcctctga agttaactga tgggctaacc gatttgtgca cacacttagg   2160

atggatttat gttaagggaa ttacttactg actgttcaat ggaaggaagt attaataata   2220

gggaataagt ttgcaactaa tctcatgctg caaacttgtg ttaattctgt ttaatataca   2280

aatttggata gcttaattat aaacatattt ttatatcaaa tatacagttc taatataaaa   2340

gttataaata attatttttg ttaacaaaga cactaaaaca gtatgttctg gttttggccc   2400

tcttgcagaa agaagcatta gaaaaattac tttaaaagta gctatatgtt actgtattgc   2460

aaaatctgtt aagagcagga ccacatcgat agtatttaat aatttgtttt acctcccaaa   2520

acacagttct tctttcagct tgtcttaaga atggttgcca aaaacaacag ccaaaaaaaa   2580

aaaacctatt ttattatcca aatgctagaa aacacacatg aattttctat aaaatcacga   2640

atatgaagta ccaggtttag tcttacttta gcaatgatag acaaaagcga ataaatacat   2700

cacagacaga aacctttata aaaatatatg attctataaa gaatcattag aaattatgag   2760

tggaaattct ccagaaagat agtattatag agtcttttga agcaattttt tgagaaatag   2820

taaaatctgg ggcagagtgt cttgcagtta attgcatatt gtcagagcag catgagaaat   2880

atgatatttg gatagggatt tcagcaacta aacattctct gttctgagat ctctttattc   2940

ctgaataatg aaagaatagt actttggtgc tgacaccaat gaggcacttc tcttggtcct   3000

agtagaggat gcagtgtact gttaaaccaa tatcatcaca tctcgagtct tatcaagttt   3060

tcattctctg tcaatatgac aagctcaaag tgacagaata tgttataggt tgaagcacac   3120

atatttgcag tttactgaaa agtagatttc ttatgtgact tttttccctt ctcagcaaag   3180

agccctacac tagatttcta ccatcactaa tatttggaag tatttcatta ctaacaatct   3240

cagtacaaca tgaaaattgt tgcttctcat ctaaaataca attttgtcta tcagaataaa   3300

cacaagtgaa attttcacct acattaacat tatgtctttg cagctttagg tttgttagat   3360

gtgttcttaa gcataatttt tagccacaaa cccattgtta gatagatatc tatggatata   3420

gatctacatc tatagatata gatatacaca catatatata ctcacacaca tatagcataa   3480

aatactcagc agggctagtt attccgattt cttgcacaat tatttagctt tttgtaagtt   3540

caacatgtaa attttaaaga cataaatata gagagactta tgtgtttgaa tataaatgat   3600

atatatggat tagcatgtac ctgtatatta ttaaacatgc aatgaactga ctggtaagtg   3660

acgtctaatt gtatggctag caatgtaatt tattcagact gtatttttgt acagagcagt   3720

gcactctaac ctatgcctct gtgtcctctt taatgcctaa agctgtgcct agaaatttca   3780

tctgtcttaa aagtaaaata tacttcatgc tgtttatgct attagtttct gtactgctat   3840

tctatattta ttatttttaa atatatgaca tgtttactac ttaaacatga attcatggta   3900

tcctggttat tttttttaag tcatctgggg gaaaacctgt ttatcactcc agtgattttg   3960

agtttgcagt ttcacaatca gttcttcatt tcatgatttt tgtagttgac atgaagtcat   4020

ctatgtggaa aaaaataaaa ataaaagtga tttcacggat gtggtttg                4068


<210>  10510
<211>  181
<212>  PRT
<213>  Homo sapiens

<400>  10510

Met Ala Ser Ala Gly Ser Gly Met Glu Glu Val Arg Val Ser Val Leu 
1               5                   10                  15


Thr Pro Leu Lys Leu Val Gly Leu Val Cys Ile Phe Leu Ala Leu Cys 
            20                  25                  30


Leu Asp Leu Gly Ala Val Leu Ser Pro Ala Trp Val Thr Ala Asp His 
        35                  40                  45


Gln Tyr Tyr Leu Ser Leu Trp Glu Ser Cys Arg Lys Pro Ala Ser Leu 
    50                  55                  60


Asp Ile Trp His Cys Glu Ser Thr Leu Ser Ser Asp Trp Gln Ile Ala 
65                  70                  75                  80


Thr Leu Ala Leu Leu Leu Gly Gly Ala Ala Ile Ile Leu Ile Ala Phe 
                85                  90                  95


Leu Val Gly Leu Ile Ser Ile Cys Val Gly Ser Arg Arg Arg Phe Tyr 
            100                 105                 110


Arg Pro Val Ala Val Met Leu Phe Ala Ala Val Val Leu Gln Val Cys 
        115                 120                 125


Ser Leu Val Leu Tyr Pro Ile Lys Phe Ile Glu Thr Val Ser Leu Lys 
    130                 135                 140


Ile Tyr His Glu Phe Asn Trp Gly Tyr Gly Leu Ala Trp Gly Ala Thr 
145                 150                 155                 160


Ile Phe Ser Phe Gly Gly Ala Ile Leu Tyr Cys Leu Asn Pro Lys Asn 
                165                 170                 175


Tyr Glu Asp Tyr Tyr 
            180


<210>  10511
<211>  3795
<212>  DNA
<213>  Homo sapiens

<400>  10511
gagatgctgc gggggttcgc tgttcggtct tccccactct ttttccttcc tctctcgagg     60

acgaatttgc ctagtgttca catttctgcc ggttccactc caccttatct gcgttttcac    120

caatgtattt cggtttggat tttatttcct tacgtttttg atggatatga agagttgaga    180

gagggacagg cttgttttcc tttccttttt tggtgacgcc gccgttgatt attggcagat    240

tgctactctg gctttactcc tgggcggcgc tgccatcatt ctcattgcat tcctggtggg    300

tttgatttct atctgcgtgg gatctcgaag gcgtttctat agacctgttg cggtcatgct    360

ttttgcagca gttgttttac aggtttgcag cctggtcctt tacccaatca agttcattga    420

aactgtgagc ttgaaaattt accatgagtt caactggggt tatggcctgg cctggggtgc    480

aactatattt tcgtttgggg gtgccatcct ttattgcctg aaccctaaga actatgaaga    540

ctactactag aaccaatagt ctcaaagtaa aaacaaccac caccatccaa caaaaggatt    600

acgtctgcat cttttctaac ttactatttt ctaaaacact tgtggagcat caagcagttt    660

gctcagttga tttaatcttt tttgcctttt ggctgtcaac atcataacca gcttttacat    720

ccattttaga aatctgcaca aattaagaga gctgattaga cataggcaaa tgctgcaaac    780

ttccaatatg ttcatatcgt ttttcttgac aaatgaaggg tctatatgac agcaaccatt    840

gtgagaaact agttggaatg agatttgcct caatctccta ttgcctgcag gggagcagtt    900

ggcataagca acatttagaa gttcctttgc gctgacaagg attccactgt tagagccctt    960

accgcctgct tatcctaccc aatgactaca ttggctgttg gttatttgct tgagtgagcc   1020

cttgaaaaat gaactgccct tcagcatcta atgggagttg tgaatgtaac tggttaatga   1080

tacacattcc accttcagga acactctttt taatgggagg ttatgctttg gcaatcagcg   1140

tctccctggg aagagagtca agacttggag acatgtgctt ctcattatgt ggttagaaat   1200

tggtgcctca gccctatcta gactggggaa aaattgagga tctctgtttt tcctggggca   1260

aacagaaaga aatctgcatg agttgctttt gtacccttta aatcatttgc caaacattgc   1320

agcaaacaag tgtgcgtatg taacaagctt cactgttttt atagaaggtg aaccattagt   1380

ataaatggta ataagttgtt ccctaaccct ccacatacat ttgcctatca cacgtaaaat   1440

taatatttac tctagtgaag tggtttgagc actaaccttg tacacattgt taagaggctt   1500

agattggtat tcatacttat ttaccataca aaagtatggt accttaaagc ttttgctcta   1560

tgttctttac tgtttcactg gaaagtgtca atagagttgc ctaagaataa aaattgaaat   1620

ggtgttaatc tgaaaattaa tgattctctg taagcactgt agttgaaaag agagtagcaa   1680

ttaggatgat cattttgtgt aaaattcatt aaaatagaag gctgctattt tttgcaagta   1740

ttttaaatgt cttcattttt ttaagaaagg aatagcgata gatttatata aatatctaaa   1800

tgtctcagta gaggagtaga attcatctgg ttatcacctg gtcctctgaa gttaactgat   1860

gggctaaccg atttgtgcac acacttagga tggatttatg ttaagggaat tacttactga   1920

ctgttcaatg gaaggaagta ttaataatag ggaataagtt tgcaactaat ctcatgctgc   1980

aaacttgtgt taattctgtt taatatacaa atttggatag cttaattata aacatatttt   2040

tatatcaaat atacagttct aatataaaag ttataaataa ttatttttgt taacaaagac   2100

actaaaacag tatgttctgg ttttggccct cttgcagaaa gaagcattag aaaaattact   2160

ttaaaagtag ctatatgtta ctgtattgca aaatctgtta agagcaggac cacatcgata   2220

gtatttaata atttgtttta cctcccaaaa cacagttctt ctttcagctt gtcttaagaa   2280

tggttgccaa aaacaacagc caaaaaaaaa aaacctattt tattatccaa atgctagaaa   2340

acacacatga attttctata aaatcacgaa tatgaagtac caggtttagt cttactttag   2400

caatgataga caaaagcgaa taaatacatc acagacagaa acctttataa aaatatatga   2460

ttctataaag aatcattaga aattatgagt ggaaattctc cagaaagata gtattataga   2520

gtcttttgaa gcaatttttt gagaaatagt aaaatctggg gcagagtgtc ttgcagttaa   2580

ttgcatattg tcagagcagc atgagaaata tgatatttgg atagggattt cagcaactaa   2640

acattctctg ttctgagatc tctttattcc tgaataatga aagaatagta ctttggtgct   2700

gacaccaatg aggcacttct cttggtccta gtagaggatg cagtgtactg ttaaaccaat   2760

atcatcacat ctcgagtctt atcaagtttt cattctctgt caatatgaca agctcaaagt   2820

gacagaatat gttataggtt gaagcacaca tatttgcagt ttactgaaaa gtagatttct   2880

tatgtgactt ttttcccttc tcagcaaaga gccctacact agatttctac catcactaat   2940

atttggaagt atttcattac taacaatctc agtacaacat gaaaattgtt gcttctcatc   3000

taaaatacaa ttttgtctat cagaataaac acaagtgaaa ttttcaccta cattaacatt   3060

atgtctttgc agctttaggt ttgttagatg tgttcttaag cataattttt agccacaaac   3120

ccattgttag atagatatct atggatatag atctacatct atagatatag atatacacac   3180

atatatatac tcacacacat atagcataaa atactcagca gggctagtta ttccgatttc   3240

ttgcacaatt atttagcttt ttgtaagttc aacatgtaaa ttttaaagac ataaatatag   3300

agagacttat gtgtttgaat ataaatgata tatatggatt agcatgtacc tgtatattat   3360

taaacatgca atgaactgac tggtaagtga cgtctaattg tatggctagc aatgtaattt   3420

attcagactg tatttttgta cagagcagtg cactctaacc tatgcctctg tgtcctcttt   3480

aatgcctaaa gctgtgccta gaaatttcat ctgtcttaaa agtaaaatat acttcatgct   3540

gtttatgcta ttagtttctg tactgctatt ctatatttat tatttttaaa tatatgacat   3600

gtttactact taaacatgaa ttcatggtat cctggttatt ttttttaagt catctggggg   3660

aaaacctgtt tatcactcca gtgattttga gtttgcagtt tcacaatcag ttcttcattt   3720

catgattttt gtagttgaca tgaagtcatc tatgtggaaa aaaataaaaa taaaagtgat   3780

ttcacggatg tggtt                                                    3795


<210>  10512
<211>  64
<212>  PRT
<213>  Homo sapiens

<400>  10512

Met Leu Phe Ala Ala Val Val Leu Gln Val Cys Ser Leu Val Leu Tyr 
1               5                   10                  15


Pro Ile Lys Phe Ile Glu Thr Val Ser Leu Lys Ile Tyr His Glu Phe 
            20                  25                  30


Asn Trp Gly Tyr Gly Leu Ala Trp Gly Ala Thr Ile Phe Ser Phe Gly 
        35                  40                  45


Gly Ala Ile Leu Tyr Cys Leu Asn Pro Lys Asn Tyr Glu Asp Tyr Tyr 
    50                  55                  60


<210>  10513
<211>  1928
<212>  DNA
<213>  Homo sapiens

<400>  10513
gcccggcttt ttcagtagga gccccgcgcg gtgcgcgctc acgcacgcgc acggcctcgc     60

ctgcgcgctc acgaggcctc tcgcggcacg cgcccccgcc ccgcgccgcc ccgccccgcc    120

ccgcctcttc cccctcccgc gcgcccgccc gccgcctgcc gccgccgccg ccgccgccgg    180

agctctgtag tatggcatcg aggagaatgg agaccaaacc tgtgataacc tgtctcaaaa    240

ccctcctcat catctactcc ttcgtcttct ggatcactgg ggtgatcctg ctggctgttg    300

gagtctgggg caaacttact ctgggcacct atatctccct tattgccgag aactccacaa    360

atgctcccta tgtgctcatc ggaactggca ccactattgt tgtctttggc ctgtttggat    420

gctttgctac atgtcgtggt agcccatgga tgctgaaact gtatgccatg tttctgtccc    480

tggtgttcct ggctgagctc gtagctggca tttcagggtt tgtgtttcgt catgagatca    540

aggacacctt cctgaggact tacacggacg ctatgcagac ttacaatggc aatgatgaga    600

ggagccgggc agtggaccat gtgcagcgca gcctgagctg ctgtggtgtg cagaactaca    660

ccaactggag caccagcccc tacttcctgg agcatggcat cccccccagc tgctgcatga    720

acgaaactga ttgtaatccc caggatctac acaatctgac tgtggccgcc accaaagtta    780

accagaaggg ttgttatgat ctggtaacta gtttcatgga gactaacatg ggaatcatcg    840

ctggagtggc gtttggaatc gcattctccc agttaattgg catgctgctg gcctgctgtc    900

tgtcccggtt catcacggcc aatcagtatg agatggtgta aggagaagtc tttcaagaat    960

gacggaataa gagacctgtt ttaaaaagga actgcagcaa tctttgaaag acttccaaag   1020

aatgttagag cacagtacat aatacacttg ccctgctccc tctccccctt accccacaac   1080

gtgcaactga cactcccacc cagtctctgc tccacctttc agcccacgtc acgtgtagtg   1140

tccattttgt gaagccctgt tgtgccacag agtgtagcca ggtccccctg cagctagtcc   1200

tagtgaacct caccccgagg ccctgcatgg gccagcccct ccatctgtac ttggtccaac   1260

tgcaactcat catcggtgac tggttatcac accatcgctg gcccctttgg gccctgcatg   1320

tagtgtggga ggctcctgtt agctcctcac tgtggtaaat gccacacacc tttaagtaga   1380

taagcagacg atagttatct gttcttttga cttaatctca tttggtttga ttttccctct   1440

actaaggctt tcctaccttc ttcaggctgc ctaagacatg taacgaaaca cttcaataat   1500

tgtccatgag gagaaaaaaa gcatgtgtca tgcatgaagg aaactgaact tgaggtggcc   1560

tccttgcttg ttacatacct gggtatgtgt aggcagttta gtgcatcttt gcctctcggt   1620

tgaaacctgt ataaccctgt tacaaagctg tgttgttgct tcttgtgaag gccatgatat   1680

tttgtttttc cccaattaat tgctattgtg ttattttact acttctctct gtattttttc   1740

ttgcattgac attatagaca ttgaggacct catccaaaca atttaaaaat gagtgtgaag   1800

ggggaacaag tcaaaatatt tttaaaagat cttcaaaagt aatgcctctg tctagcatgc   1860

caacaagaat gcattgatat tgtgaacatt tgtgatatat gtattaataa atagagcaat   1920

tacaagca                                                            1928


<210>  10514
<211>  249
<212>  PRT
<213>  Homo sapiens

<400>  10514

Met Ala Ser Arg Arg Met Glu Thr Lys Pro Val Ile Thr Cys Leu Lys 
1               5                   10                  15


Thr Leu Leu Ile Ile Tyr Ser Phe Val Phe Trp Ile Thr Gly Val Ile 
            20                  25                  30


Leu Leu Ala Val Gly Val Trp Gly Lys Leu Thr Leu Gly Thr Tyr Ile 
        35                  40                  45


Ser Leu Ile Ala Glu Asn Ser Thr Asn Ala Pro Tyr Val Leu Ile Gly 
    50                  55                  60


Thr Gly Thr Thr Ile Val Val Phe Gly Leu Phe Gly Cys Phe Ala Thr 
65                  70                  75                  80


Cys Arg Gly Ser Pro Trp Met Leu Lys Leu Tyr Ala Met Phe Leu Ser 
                85                  90                  95


Leu Val Phe Leu Ala Glu Leu Val Ala Gly Ile Ser Gly Phe Val Phe 
            100                 105                 110


Arg His Glu Ile Lys Asp Thr Phe Leu Arg Thr Tyr Thr Asp Ala Met 
        115                 120                 125


Gln Thr Tyr Asn Gly Asn Asp Glu Arg Ser Arg Ala Val Asp His Val 
    130                 135                 140


Gln Arg Ser Leu Ser Cys Cys Gly Val Gln Asn Tyr Thr Asn Trp Ser 
145                 150                 155                 160


Thr Ser Pro Tyr Phe Leu Glu His Gly Ile Pro Pro Ser Cys Cys Met 
                165                 170                 175


Asn Glu Thr Asp Cys Asn Pro Gln Asp Leu His Asn Leu Thr Val Ala 
            180                 185                 190


Ala Thr Lys Val Asn Gln Lys Gly Cys Tyr Asp Leu Val Thr Ser Phe 
        195                 200                 205


Met Glu Thr Asn Met Gly Ile Ile Ala Gly Val Ala Phe Gly Ile Ala 
    210                 215                 220


Phe Ser Gln Leu Ile Gly Met Leu Leu Ala Cys Cys Leu Ser Arg Phe 
225                 230                 235                 240


Ile Thr Ala Asn Gln Tyr Glu Met Val 
                245


<210>  10515
<211>  1168
<212>  DNA
<213>  Homo sapiens

<400>  10515
ggcatcgagg agaatggaga ccaaacctgt gataacctgt ctcaaaaccc tcctcatcat     60

ctactccttc gtcttctgga tcactggggt gatcctgctg gctgttggag tctggggcaa    120

acttactctg ggcacctata tctcccggtt catcacggcc aatcagtatg agatggtgta    180

aggagaagtc tttcaagaat gacggaataa gagacctgtt ttaaaaagga actgcagcaa    240

tctttgaaag acttccaaag aatgttagag cacagtacat aatacacttg ccctgctccc    300

tctccccctt accccacaac gtgcaactga cactcccacc cagtctctgc tccacctttc    360

agcccacgtc acgtgtagtg tccattttgt gaagccctgt tgtgccacag agtgtagcca    420

ggtccccctg cagctagtcc tagtgaacct caccccgagg ccctgcatgg gccagcccct    480

ccatctgtac ttggtccaac tgcaactcat catcggtgac tggttatcac accatcgctg    540

gcccctttgg gccctgcatg tagtgtggga ggctcctgtt agctcctcac tgtggtaaat    600

gccacacacc tttaagtaga taagcagacg atagttatct gttcttttga cttaatctca    660

tttggtttga ttttccctct actaaggctt tcctaccttc ttcaggctgc ctaagacatg    720

taacgaaaca cttcaataat tgtccatgag gagaaaaaaa gcatgtgtca tgcatgaagg    780

aaactgaact tgaggtggcc tccttgcttg ttacatacct gggtatgtgt aggcagttta    840

gtgcatcttt gcctctcggt tgaaacctgt ataaccctgt tacaaagctg tgttgttgct    900

tcttgtgaag gccatgatat tttgtttttc cccaattaat tgctattgtg ttattttact    960

acttctctct gtattttttc ttgcattgac attatagaca ttgaggacct catccaaaca   1020

atttaaaaat gagtgtgaag ggggaacaag tcaaaatatt tttaaaagat cttcaaaagt   1080

aatgcctctg tctagcatgc caacaagaat gcattgatat tgtgaacatt tgtgatatat   1140

gtattaataa atagagcaat tacaagca                                      1168


<210>  10516
<211>  55
<212>  PRT
<213>  Homo sapiens

<400>  10516

Met Glu Thr Lys Pro Val Ile Thr Cys Leu Lys Thr Leu Leu Ile Ile 
1               5                   10                  15


Tyr Ser Phe Val Phe Trp Ile Thr Gly Val Ile Leu Leu Ala Val Gly 
            20                  25                  30


Val Trp Gly Lys Leu Thr Leu Gly Thr Tyr Ile Ser Arg Phe Ile Thr 
        35                  40                  45


Ala Asn Gln Tyr Glu Met Val 
    50                  55


<210>  10517
<211>  3972
<212>  DNA
<213>  Homo sapiens

<400>  10517
aagggcccag agctctggcc ggcggacctt ttccttctgg agtttccccg gcgggtatta     60

gtccttgtgg caccaagtca gaatttcatt caaaagacaa ttaggaagat ggttttctat    120

ggaaaatatt taagtgtagg tcttaatgtg aaagaaagag ggagagaaag aaaccccttt    180

attatgttct cccttcctta ggcatttttt gtcccgtggg aaaaaactgt actagggaca    240

gagacctctg ttaagtttta gagaaaaggg atcttttttt tttttatttg agacagagtc    300

ttgctctgtc gcccaggctg gagtgcagtg gcacgatctc ggctcactgc aactccgcct    360

cctgggttca agcaattctc ctgcttcatc ctcccgagta gctgggatta caggcgctgg    420

ccaccacgcc cggctaattt ttgtattttt agtagagacc gggtttcacc atgttggcca    480

ggctagtctg gaacccctga ctttgtgatc cgcccgcctc ggcctcccaa agtgctggga    540

ttacaggcgt gagccaccgt ttcaggccga gaaaagggat ttaaaatgag aagcttgaat    600

cttattgaac ataattgtag gactgccaga gaggactggt ggatgaggaa tatggcaagg    660

gacatgagat gggaaaaatt aaataggctg tggtttggaa gtctcaaagt gaaattcaag    720

gtgcaaggct cttaaaagtt aaatccagcg attcggtaca tagcttaggc cctattaaat    780

gacccagtgc tttaagaact atcttttgaa aggaacactt cacacaagca ccctcaaaaa    840

taattagaca cctccccatt tctctgttaa atggtgaaag acacccaaga ctagacctaa    900

ctactgtcac cctctcctgg cctcttggca gccaaaaggc cacatggccc aggctctcca    960

gcatcactgt gtagccgact tggacaaaaa tggacttctc cccattgcca cttgcagatc   1020

tcttcaaaga atcagcagat ctgatagtgt gcccctcttc atccccggca accactgtta   1080

aaggaaagat tgggaaagat cccaccccgc caggagggag gcaaaagcct ctgacgctcc   1140

cctcccccca tagctgacca aggccagggc cactgcggga gcaccgcgcg tccacgtgca   1200

cccagcatgc ccggtcaccc tttattacgt aagagtccca ggatggagtt gtacctgctg   1260

ccggcccctc ttccccgacg gctaataata aacccgggtt cctgtttccc ggccgcggcc   1320

actccagatt cggggctgag gggctcactc tgcaaccaag gcacgtgcat tctggtcatc   1380

ccacgcgggg agcgcgcgca aggcccgccc agcccccaca tgccagcccc accctccagt   1440

cggtccggac gccgacgcct ttttgaccct cgctgtgccc ggccctcctc atctggcctg   1500

cccagggctt ggtgctggcg gggtccagct gctccaatcc ctcctcctct gctctgccct   1560

gccctgccct ggcctgcccc ggcgccctcc ctcagcccgg gtatcaggcg agaggcggag   1620

ctggcccggc gcgccccgcc cccgctgtag aaagggccgg gcgagtgtta ctcgcggtca   1680

tcccggcctg ggccttttat ctcggtgctg ccgggggagg cgggaggagg agacaccagg   1740

ggtggccctg agcgccggcg acacctttcc tggactataa attgagcacc tgggatgggt   1800

agggggccaa cgcagtcacc gccgtccgca gtcacagtcc agccactgac cgcagcagcg   1860

cccttgcgta gcagccgctt gcagcgagaa cactgaattg ccaacgagca ggagagtctc   1920

aaggcgcaag aggaggtggg tgcccacgcc ccatcgctgc cccggccagc ttggttgctt   1980

gagctcaggc ttttcggagg gagaagttgt ggtggtgggg ggacaccctt ctccccgcgg   2040

ccgtaggtgg gcgaggaggt gggactgccc agccgcgggg agccacccag gcgccgtccc   2100

ggacgagctg tagccagaga agggggtgcg cgcgggcaag ggcgccaggc cccctagcag   2160

ggtgaataat ctaatctgtt ctttcgtctc cgtgtatcaa acaggccagg gctcgaccca   2220

cagagcaccc tcagccatcg cgagtttccg ggcgccaaag ccaggagaag ccgcccatcc   2280

cgcagggccg gtctgccagc gagacgagag ttggcgaggg cggaggagtg ccgggaatcc   2340

cgccacaccg gctatagcca ggcccccagc gcgggccttg gagagcgcgt gaaggcgggc   2400

atccccttga cccggccgac catccccgtg cccctgcgtc cctgcgctcc aacgtccgcg   2460

cggccaccat gatgcaaatc tgcgacacct acaaccagaa gcactcgctc tttaacgcca   2520

tgaatcgctt cattggcgcc gtgaacaaca tggaccagac ggtgatggtg cccagcttgc   2580

tgcgcgacgt gcccctggct gaccccgggt tagacaacga tgttggcgtg gaggtaggcg   2640

gcagtggcgg ctgcctggag gagcgcacgc ccccagtccc cgactcggga agcgccaatg   2700

gcagcttttt cgcgccctct cgggacatgt acagccacta cgtgcttctc aagtccatcc   2760

gcaacgacat cgagtggggg gtcctgcacc agccgcctcc accggctggg agcgaggagg   2820

gcagtgcctg gaagtccaag gacatcctgg tggacctggg ccacttggag ggtgcggacg   2880

ccggcgaaga agacctggaa cagcagttcc actaccacct gcgcgggctg cacactgtgc   2940

tctcgaaact cacgcgcaaa gccaacatcc tcactaacag atacaagcag gagatcggct   3000

tcggcaattg gggccactga ggcgtggcgc ccgtggctgc ccagcacctt cttcgaccca   3060

tctcaccctc tctcattcct caaagctttt tttttttttc ctggctgggg ggcgggaagg   3120

gcagactgca aactgggggg ctgcgtacgt gcaggaggcg cggtggggct gcgtggagga   3180

gggggccacg tgtgagagag aagaaaatgg tggccggaga tgggagggcc caaggaacct   3240

cctgggaggg ggcctgcatt ctatgttggt gggaatggga ctgggctgac gccctgcatt   3300

cagcctgtgc ctttcctggg gtttcttttc tgttcttttc ggaggagagg gcccgagaag   3360

gggccatacc agggcgcggc gctgggttgc cacacttggg aaagcagccc ggagctgggt   3420

gctggggaag gcggggcgcg tagcctcccg ccgccctgcg gttgggccgg tggaggccca   3480

ggcgttgcta ggattgcatc agttttcctg tttgcactat ttctttttgt aacattggcc   3540

ctgtgtgaag tatttcgaat ctcctccttg ctctgaaact tcagcgattc cattgtgata   3600

agcgcacaaa cagcactgtc tgtcggtaat cggtactact ttattaatga ttttctgtta   3660

cactgtatag tagtcctatg gcacccccac cccatccctt tcgtgccact cccgtcccca   3720

cccccacccc agtgtgtata agctggcatt tcgccagctt gtacgtagct tgccactcag   3780

tgaaaataat aacattatta tgagaaagtg gacttaaccg aaatggaacc aactgacatt   3840

ctatcgtgtt gtacatagaa tgatgaaggg ttccactgtt gttgtatgtc ttaaatttat   3900

ttaaaacttt ttttaatcca gatgtagact atattctaaa aaataaaaaa gcaaatgtgt   3960

caactaaatt gg                                                       3972


<210>  10518
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10518

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10519
<211>  1824
<212>  DNA
<213>  Homo sapiens

<400>  10519
aagggcccag agctctggcc ggcggacctt ttccttctgg agtttccccg gcgggtgcca     60

gggctcgacc cacagagcac cctcagccat cgcgagtttc cgggcgccaa agccaggaga    120

agccgcccat cccgcagggc cggtctgcca gcgagacgag agttggcgag ggcggaggag    180

tgccgggaat cccgccacac cggctatagc caggccccca gcgcgggcct tggagagcgc    240

gtgaaggcgg gcatcccctt gacccggccg accatccccg tgcccctgcg tccctgcgct    300

ccaacgtccg cgcggccacc atgatgcaaa tctgcgacac ctacaaccag aagcactcgc    360

tctttaacgc catgaatcgc ttcattggcg ccgtgaacaa catggaccag acggtgatgg    420

tgcccagctt gctgcgcgac gtgcccctgg ctgaccccgg gttagacaac gatgttggcg    480

tggaggtagg cggcagtggc ggctgcctgg aggagcgcac gcccccagtc cccgactcgg    540

gaagcgccaa tggcagcttt ttcgcgccct ctcgggacat gtacagccac tacgtgcttc    600

tcaagtccat ccgcaacgac atcgagtggg gggtcctgca ccagccgcct ccaccggctg    660

ggagcgagga gggcagtgcc tggaagtcca aggacatcct ggtggacctg ggccacttgg    720

agggtgcgga cgccggcgaa gaagacctgg aacagcagtt ccactaccac ctgcgcgggc    780

tgcacactgt gctctcgaaa ctcacgcgca aagccaacat cctcactaac agatacaagc    840

aggagatcgg cttcggcaat tggggccact gaggcgtggc gcccgtggct gcccagcacc    900

ttcttcgacc catctcaccc tctctcattc ctcaaagctt tttttttttt tcctggctgg    960

ggggcgggaa gggcagactg caaactgggg ggctgcgtac gtgcaggagg cgcggtgggg   1020

ctgcgtggag gagggggcca cgtgtgagag agaagaaaat ggtggccgga gatgggaggg   1080

cccaaggaac ctcctgggag ggggcctgca ttctatgttg gtgggaatgg gactgggctg   1140

acgccctgca ttcagcctgt gcctttcctg gggtttcttt tctgttcttt tcggaggaga   1200

gggcccgaga aggggccata ccagggcgcg gcgctgggtt gccacacttg ggaaagcagc   1260

ccggagctgg gtgctgggga aggcggggcg cgtagcctcc cgccgccctg cggttgggcc   1320

ggtggaggcc caggcgttgc taggattgca tcagttttcc tgtttgcact atttcttttt   1380

gtaacattgg ccctgtgtga agtatttcga atctcctcct tgctctgaaa cttcagcgat   1440

tccattgtga taagcgcaca aacagcactg tctgtcggta atcggtacta ctttattaat   1500

gattttctgt tacactgtat agtagtccta tggcaccccc accccatccc tttcgtgcca   1560

ctcccgtccc cacccccacc ccagtgtgta taagctggca tttcgccagc ttgtacgtag   1620

cttgccactc agtgaaaata ataacattat tatgagaaag tggacttaac cgaaatggaa   1680

ccaactgaca ttctatcgtg ttgtacatag aatgatgaag ggttccactg ttgttgtatg   1740

tcttaaattt atttaaaact ttttttaatc cagatgtaga ctatattcta aaaaataaaa   1800

aagcaaatgt gtcaactaaa ttgg                                          1824


<210>  10520
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10520

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10521
<211>  1902
<212>  DNA
<213>  Homo sapiens

<400>  10521
aagggcccag agctctggcc ggcggacctt ttccttctgg agtttccccg gcgggtgcca     60

gggctcgacc cacagagcac cctcagccat cgcgagtttc cgggcgccaa agccaggaga    120

agccgcccat cccgcagggc cggtctgcca gcgagacgag agttggcgag ggcggaggag    180

tgccgggaat cccgccacac cggctatagc caggccccca gcgcgggcct tggagagcgc    240

gtgaaggcgg gcatcccctt gacccggccg accatccccg tgcccctgcg tccctgcgct    300

ccaacgtccg cgcggccacc atgatgcaaa tctgcgacac ctacaaccag aagcactcgc    360

tctttaacgc catgaatcgc ttcattggcg ccgtgaacaa catggaccag acggtgatgg    420

tgcccagctt gctgcgcgac gtgcccctgg ctgaccccgg gttagacaac gatgttggcg    480

tggaggtagg cggcagtggc ggctgcctgg aggagcgcac gcccccagtc cccgactcgg    540

gaagcgccaa tggcagcttt ttcgcgccct ctcgggacat gtacagccac tacgtgcttc    600

tcaagtccat ccgcaacgac atcgagtggg gggtcctgca ccagccgcct ccaccggctg    660

ggagcgagga gggcagtgcc tggaagtcca aggacatcct ggtggacctg ggccacttgg    720

agggtgcgga cgccggcgaa gaagacctgg aacagcagtt ccactaccac ctgcgcgggc    780

tgcacactgt gctctcgaaa ctcacgcgca aagccaacat cctcactaac agatacaagc    840

aggagatcgg cttcggcaat tggggccact gaggcgtggc gcccgtggct gcccagcacc    900

ttcttcgacc catctcaccc tctctcattc ctcaaagctt tttttttttt tcctggctgg    960

ggggcgggaa gggcagactg caaactgggg ggctgcgtac gtgcaggagg cgcggtgggg   1020

ctgcgtggag gagggggcca cgtgtgagag agaagaaaat ggtggccgga gatgggaggg   1080

cccaaggaac ctcctgggag ggggcctgca ttctatgttg gtgggaatgg gactgggctg   1140

acgccctgca ttcagcctgt gcctttcctg gggtttcttt tctgttcttt tcggaggaga   1200

gggcccgaga aggggccata ccagggcgcg gcgctgggtt gccacacttg ggaaagcagc   1260

ccggagctgg gtgctgggga aggcggggcg cgtagcctcc cgccgccctg cggttgggcc   1320

ggtggaggcc caggcgttgc taggattgca tcagttttcc tgtttgcact atttcttttt   1380

gtaacattgg ccctgtgtga agtatttcga atctcctcct tgctctgaaa cttcagcgat   1440

tccattgtga taagcgcaca aacagcactg tctgtcggta atcggtacta ctttattaat   1500

gattttctgt tacactgtat agtagtccta tggcaccccc accccatccc tttcgtgcca   1560

ctcccgtccc cacccccacc ccagtgtgta taagctggca tttcgccagc ttgtacgtag   1620

cttgccactc agtgaaaata ataacattat tatgagaaag tggacttaac cgaaatggaa   1680

ccaactgaca ttctatcgtg ttgtacatag aatgatgaag ggttccactg ttgttgtatg   1740

tcttaaattt atttaaaact ttttttaatc cagatgtaga ctatattcta aaaaataaaa   1800

aagcaaatgt gtcaactaaa ttggacaagc gtctggtcct cattaatctg ccaatgaatg   1860

gtttcgtcat taaataaaaa tcaatttaat tgatttacta gc                      1902


<210>  10522
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10522

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10523
<211>  4050
<212>  DNA
<213>  Homo sapiens

<400>  10523
aagggcccag agctctggcc ggcggacctt ttccttctgg agtttccccg gcgggtatta     60

gtccttgtgg caccaagtca gaatttcatt caaaagacaa ttaggaagat ggttttctat    120

ggaaaatatt taagtgtagg tcttaatgtg aaagaaagag ggagagaaag aaaccccttt    180

attatgttct cccttcctta ggcatttttt gtcccgtggg aaaaaactgt actagggaca    240

gagacctctg ttaagtttta gagaaaaggg atcttttttt tttttatttg agacagagtc    300

ttgctctgtc gcccaggctg gagtgcagtg gcacgatctc ggctcactgc aactccgcct    360

cctgggttca agcaattctc ctgcttcatc ctcccgagta gctgggatta caggcgctgg    420

ccaccacgcc cggctaattt ttgtattttt agtagagacc gggtttcacc atgttggcca    480

ggctagtctg gaacccctga ctttgtgatc cgcccgcctc ggcctcccaa agtgctggga    540

ttacaggcgt gagccaccgt ttcaggccga gaaaagggat ttaaaatgag aagcttgaat    600

cttattgaac ataattgtag gactgccaga gaggactggt ggatgaggaa tatggcaagg    660

gacatgagat gggaaaaatt aaataggctg tggtttggaa gtctcaaagt gaaattcaag    720

gtgcaaggct cttaaaagtt aaatccagcg attcggtaca tagcttaggc cctattaaat    780

gacccagtgc tttaagaact atcttttgaa aggaacactt cacacaagca ccctcaaaaa    840

taattagaca cctccccatt tctctgttaa atggtgaaag acacccaaga ctagacctaa    900

ctactgtcac cctctcctgg cctcttggca gccaaaaggc cacatggccc aggctctcca    960

gcatcactgt gtagccgact tggacaaaaa tggacttctc cccattgcca cttgcagatc   1020

tcttcaaaga atcagcagat ctgatagtgt gcccctcttc atccccggca accactgtta   1080

aaggaaagat tgggaaagat cccaccccgc caggagggag gcaaaagcct ctgacgctcc   1140

cctcccccca tagctgacca aggccagggc cactgcggga gcaccgcgcg tccacgtgca   1200

cccagcatgc ccggtcaccc tttattacgt aagagtccca ggatggagtt gtacctgctg   1260

ccggcccctc ttccccgacg gctaataata aacccgggtt cctgtttccc ggccgcggcc   1320

actccagatt cggggctgag gggctcactc tgcaaccaag gcacgtgcat tctggtcatc   1380

ccacgcgggg agcgcgcgca aggcccgccc agcccccaca tgccagcccc accctccagt   1440

cggtccggac gccgacgcct ttttgaccct cgctgtgccc ggccctcctc atctggcctg   1500

cccagggctt ggtgctggcg gggtccagct gctccaatcc ctcctcctct gctctgccct   1560

gccctgccct ggcctgcccc ggcgccctcc ctcagcccgg gtatcaggcg agaggcggag   1620

ctggcccggc gcgccccgcc cccgctgtag aaagggccgg gcgagtgtta ctcgcggtca   1680

tcccggcctg ggccttttat ctcggtgctg ccgggggagg cgggaggagg agacaccagg   1740

ggtggccctg agcgccggcg acacctttcc tggactataa attgagcacc tgggatgggt   1800

agggggccaa cgcagtcacc gccgtccgca gtcacagtcc agccactgac cgcagcagcg   1860

cccttgcgta gcagccgctt gcagcgagaa cactgaattg ccaacgagca ggagagtctc   1920

aaggcgcaag aggaggtggg tgcccacgcc ccatcgctgc cccggccagc ttggttgctt   1980

gagctcaggc ttttcggagg gagaagttgt ggtggtgggg ggacaccctt ctccccgcgg   2040

ccgtaggtgg gcgaggaggt gggactgccc agccgcgggg agccacccag gcgccgtccc   2100

ggacgagctg tagccagaga agggggtgcg cgcgggcaag ggcgccaggc cccctagcag   2160

ggtgaataat ctaatctgtt ctttcgtctc cgtgtatcaa acaggccagg gctcgaccca   2220

cagagcaccc tcagccatcg cgagtttccg ggcgccaaag ccaggagaag ccgcccatcc   2280

cgcagggccg gtctgccagc gagacgagag ttggcgaggg cggaggagtg ccgggaatcc   2340

cgccacaccg gctatagcca ggcccccagc gcgggccttg gagagcgcgt gaaggcgggc   2400

atccccttga cccggccgac catccccgtg cccctgcgtc cctgcgctcc aacgtccgcg   2460

cggccaccat gatgcaaatc tgcgacacct acaaccagaa gcactcgctc tttaacgcca   2520

tgaatcgctt cattggcgcc gtgaacaaca tggaccagac ggtgatggtg cccagcttgc   2580

tgcgcgacgt gcccctggct gaccccgggt tagacaacga tgttggcgtg gaggtaggcg   2640

gcagtggcgg ctgcctggag gagcgcacgc ccccagtccc cgactcggga agcgccaatg   2700

gcagcttttt cgcgccctct cgggacatgt acagccacta cgtgcttctc aagtccatcc   2760

gcaacgacat cgagtggggg gtcctgcacc agccgcctcc accggctggg agcgaggagg   2820

gcagtgcctg gaagtccaag gacatcctgg tggacctggg ccacttggag ggtgcggacg   2880

ccggcgaaga agacctggaa cagcagttcc actaccacct gcgcgggctg cacactgtgc   2940

tctcgaaact cacgcgcaaa gccaacatcc tcactaacag atacaagcag gagatcggct   3000

tcggcaattg gggccactga ggcgtggcgc ccgtggctgc ccagcacctt cttcgaccca   3060

tctcaccctc tctcattcct caaagctttt tttttttttc ctggctgggg ggcgggaagg   3120

gcagactgca aactgggggg ctgcgtacgt gcaggaggcg cggtggggct gcgtggagga   3180

gggggccacg tgtgagagag aagaaaatgg tggccggaga tgggagggcc caaggaacct   3240

cctgggaggg ggcctgcatt ctatgttggt gggaatggga ctgggctgac gccctgcatt   3300

cagcctgtgc ctttcctggg gtttcttttc tgttcttttc ggaggagagg gcccgagaag   3360

gggccatacc agggcgcggc gctgggttgc cacacttggg aaagcagccc ggagctgggt   3420

gctggggaag gcggggcgcg tagcctcccg ccgccctgcg gttgggccgg tggaggccca   3480

ggcgttgcta ggattgcatc agttttcctg tttgcactat ttctttttgt aacattggcc   3540

ctgtgtgaag tatttcgaat ctcctccttg ctctgaaact tcagcgattc cattgtgata   3600

agcgcacaaa cagcactgtc tgtcggtaat cggtactact ttattaatga ttttctgtta   3660

cactgtatag tagtcctatg gcacccccac cccatccctt tcgtgccact cccgtcccca   3720

cccccacccc agtgtgtata agctggcatt tcgccagctt gtacgtagct tgccactcag   3780

tgaaaataat aacattatta tgagaaagtg gacttaaccg aaatggaacc aactgacatt   3840

ctatcgtgtt gtacatagaa tgatgaaggg ttccactgtt gttgtatgtc ttaaatttat   3900

ttaaaacttt ttttaatcca gatgtagact atattctaaa aaataaaaaa gcaaatgtgt   3960

caactaaatt ggacaagcgt ctggtcctca ttaatctgcc aatgaatggt ttcgtcatta   4020

aataaaaatc aatttaattg atttactagc                                    4050


<210>  10524
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10524

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10525
<211>  1906
<212>  DNA
<213>  Homo sapiens

<400>  10525
cggacctttt ccttctggag tttccccggc gggttcacag tccagccact gaccgcagca     60

gcgcccttgc gtagcagccg cttgcagcga gaacactgaa ttgccaacga gcaggagagt    120

ctcaaggcgc aagaggaggc cagggctcga cccacagagc accctcagcc atcgcgagtt    180

tccgggcgcc aaagccagga gaagccgccc atcccgcagg gccggtctgc cagcgagacg    240

agagttggcg agggcggagg agtgccggga atcccgccac accggctata gccaggcccc    300

cagcgcgggc cttggagagc gcgtgaaggc gggcatcccc ttgacccggc cgaccatccc    360

cgtgcccctg cgtccctgcg ctccaacgtc cgcgcggcca ccatgatgca aatctgcgac    420

acctacaacc agaagcactc gctctttaac gccatgaatc gcttcattgg cgccgtgaac    480

aacatggacc agacggtgat ggtgcccagc ttgctgcgcg acgtgcccct ggctgacccc    540

gggttagaca acgatgttgg cgtggaggta ggcggcagtg gcggctgcct ggaggagcgc    600

acgcccccag tccccgactc gggaagcgcc aatggcagct ttttcgcgcc ctctcgggac    660

atgtacagcc actacgtgct tctcaagtcc atccgcaacg acatcgagtg gggggtcctg    720

caccagccgc ctccaccggc tgggagcgag gagggcagtg cctggaagtc caaggacatc    780

ctggtggacc tgggccactt ggagggtgcg gacgccggcg aagaagacct ggaacagcag    840

ttccactacc acctgcgcgg gctgcacact gtgctctcga aactcacgcg caaagccaac    900

atcctcacta acagatacaa gcaggagatc ggcttcggca attggggcca ctgaggcgtg    960

gcgcccgtgg ctgcccagca ccttcttcga cccatctcac cctctctcat tcctcaaagc   1020

tttttttttt tttcctggct ggggggcggg aagggcagac tgcaaactgg ggggctgcgt   1080

acgtgcagga ggcgcggtgg ggctgcgtgg aggagggggc cacgtgtgag agagaagaaa   1140

atggtggccg gagatgggag ggcccaagga acctcctggg agggggcctg cattctatgt   1200

tggtgggaat gggactgggc tgacgccctg cattcagcct gtgcctttcc tggggtttct   1260

tttctgttct tttcggagga gagggcccga gaaggggcca taccagggcg cggcgctggg   1320

ttgccacact tgggaaagca gcccggagct gggtgctggg gaaggcgggg cgcgtagcct   1380

cccgccgccc tgcggttggg ccggtggagg cccaggcgtt gctaggattg catcagtttt   1440

cctgtttgca ctatttcttt ttgtaacatt ggccctgtgt gaagtatttc gaatctcctc   1500

cttgctctga aacttcagcg attccattgt gataagcgca caaacagcac tgtctgtcgg   1560

taatcggtac tactttatta atgattttct gttacactgt atagtagtcc tatggcaccc   1620

ccaccccatc cctttcgtgc cactcccgtc cccaccccca ccccagtgtg tataagctgg   1680

catttcgcca gcttgtacgt agcttgccac tcagtgaaaa taataacatt attatgagaa   1740

agtggactta accgaaatgg aaccaactga cattctatcg tgttgtacat agaatgatga   1800

agggttccac tgttgttgta tgtcttaaat ttatttaaaa ctttttttaa tccagatgta   1860

gactatattc taaaaaataa aaaagcaaat gtgtcaacta aattgg                  1906


<210>  10526
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10526

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10527
<211>  1984
<212>  DNA
<213>  Homo sapiens

<400>  10527
cggacctttt ccttctggag tttccccggc gggttcacag tccagccact gaccgcagca     60

gcgcccttgc gtagcagccg cttgcagcga gaacactgaa ttgccaacga gcaggagagt    120

ctcaaggcgc aagaggaggc cagggctcga cccacagagc accctcagcc atcgcgagtt    180

tccgggcgcc aaagccagga gaagccgccc atcccgcagg gccggtctgc cagcgagacg    240

agagttggcg agggcggagg agtgccggga atcccgccac accggctata gccaggcccc    300

cagcgcgggc cttggagagc gcgtgaaggc gggcatcccc ttgacccggc cgaccatccc    360

cgtgcccctg cgtccctgcg ctccaacgtc cgcgcggcca ccatgatgca aatctgcgac    420

acctacaacc agaagcactc gctctttaac gccatgaatc gcttcattgg cgccgtgaac    480

aacatggacc agacggtgat ggtgcccagc ttgctgcgcg acgtgcccct ggctgacccc    540

gggttagaca acgatgttgg cgtggaggta ggcggcagtg gcggctgcct ggaggagcgc    600

acgcccccag tccccgactc gggaagcgcc aatggcagct ttttcgcgcc ctctcgggac    660

atgtacagcc actacgtgct tctcaagtcc atccgcaacg acatcgagtg gggggtcctg    720

caccagccgc ctccaccggc tgggagcgag gagggcagtg cctggaagtc caaggacatc    780

ctggtggacc tgggccactt ggagggtgcg gacgccggcg aagaagacct ggaacagcag    840

ttccactacc acctgcgcgg gctgcacact gtgctctcga aactcacgcg caaagccaac    900

atcctcacta acagatacaa gcaggagatc ggcttcggca attggggcca ctgaggcgtg    960

gcgcccgtgg ctgcccagca ccttcttcga cccatctcac cctctctcat tcctcaaagc   1020

tttttttttt tttcctggct ggggggcggg aagggcagac tgcaaactgg ggggctgcgt   1080

acgtgcagga ggcgcggtgg ggctgcgtgg aggagggggc cacgtgtgag agagaagaaa   1140

atggtggccg gagatgggag ggcccaagga acctcctggg agggggcctg cattctatgt   1200

tggtgggaat gggactgggc tgacgccctg cattcagcct gtgcctttcc tggggtttct   1260

tttctgttct tttcggagga gagggcccga gaaggggcca taccagggcg cggcgctggg   1320

ttgccacact tgggaaagca gcccggagct gggtgctggg gaaggcgggg cgcgtagcct   1380

cccgccgccc tgcggttggg ccggtggagg cccaggcgtt gctaggattg catcagtttt   1440

cctgtttgca ctatttcttt ttgtaacatt ggccctgtgt gaagtatttc gaatctcctc   1500

cttgctctga aacttcagcg attccattgt gataagcgca caaacagcac tgtctgtcgg   1560

taatcggtac tactttatta atgattttct gttacactgt atagtagtcc tatggcaccc   1620

ccaccccatc cctttcgtgc cactcccgtc cccaccccca ccccagtgtg tataagctgg   1680

catttcgcca gcttgtacgt agcttgccac tcagtgaaaa taataacatt attatgagaa   1740

agtggactta accgaaatgg aaccaactga cattctatcg tgttgtacat agaatgatga   1800

agggttccac tgttgttgta tgtcttaaat ttatttaaaa ctttttttaa tccagatgta   1860

gactatattc taaaaaataa aaaagcaaat gtgtcaacta aattggacaa gcgtctggtc   1920

ctcattaatc tgccaatgaa tggtttcgtc attaaataaa aatcaattta attgatttac   1980

tagc                                                                1984


<210>  10528
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10528

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10529
<211>  375
<212>  DNA
<213>  Homo sapiens

<400>  10529
ggccttgcgc gcgctccccg cgtgggatga ccagaatgca cgtgccttgg ttgcagagtg     60

agcccctcag ccccgaatct ggagtggccg cggccgggaa acaggaaccc gggtttatta    120

ttagccgtcg gggaagaggg gccggcagca gttccaacag tgtgataaca cacggaaaac    180

ggaaatccaa gggatctagc aaaaggattc cacccagcaa aaacgccagc ttgggagagg    240

gcccctacct aactccttcc ttctggcctc cacccctccc ctgatacgtt tccttccgtc    300

tagtctcgag ataacccttc atcccccagt ttcttgactc tggccgctgt tcttgaacat    360

ttcttaaaca ctttc                                                     375


<210>  10530
<211>  85
<212>  PRT
<213>  Homo sapiens

<400>  10530

Met Thr Arg Met His Val Pro Trp Leu Gln Ser Glu Pro Leu Ser Pro 
1               5                   10                  15


Glu Ser Gly Val Ala Ala Ala Gly Lys Gln Glu Pro Gly Phe Ile Ile 
            20                  25                  30


Ser Arg Arg Gly Arg Gly Ala Gly Ser Ser Ser Asn Ser Val Ile Thr 
        35                  40                  45


His Gly Lys Arg Lys Ser Lys Gly Ser Ser Lys Arg Ile Pro Pro Ser 
    50                  55                  60


Lys Asn Ala Ser Leu Gly Glu Gly Pro Tyr Leu Thr Pro Ser Phe Trp 
65                  70                  75                  80


Pro Pro Pro Leu Pro 
                85


<210>  10531
<211>  453
<212>  DNA
<213>  Homo sapiens

<400>  10531
atgggtccag gaagggggac aaagtacgct ttaatttatg agaagatcag ctactagaaa     60

ttcagcgatt ccattgtgat aagcgcacaa acagcactgt ctgtcggtaa tcggtactac    120

tttattaatg attttctgtt acactgtata gtagtcctat ggcaccccca ccccatccct    180

ttcgtgccac tcccgtcccc acccccaccc cagtgtgtat aagctggcat ttcgccagct    240

tgtacgtagc ttgccactca gtgaaaataa taacattatt atgagaaagt ggacttaacc    300

gaaatggaac caactgacat tctatcgtgt tgtacataga atgatgaagg gttccactgt    360

tgttgtatgt cttaaattta tttaaaactt tttttaatcc agatgtagac tatattctaa    420

aaaataaaaa agcaaatgtg tcaactaaat tgg                                 453


<210>  10532
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  10532

Met Ala Pro Pro Pro His Pro Phe Arg Ala Thr Pro Val Pro Thr Pro 
1               5                   10                  15


Thr Pro Val Cys Ile Ser Trp His Phe Ala Ser Leu Tyr Val Ala Cys 
            20                  25                  30


His Ser Val Lys Ile Ile Thr Leu Leu 
        35                  40


<210>  10533
<211>  531
<212>  DNA
<213>  Homo sapiens

<400>  10533
atgggtccag gaagggggac aaagtacgct ttaatttatg agaagatcag ctactagaaa     60

ttcagcgatt ccattgtgat aagcgcacaa acagcactgt ctgtcggtaa tcggtactac    120

tttattaatg attttctgtt acactgtata gtagtcctat ggcaccccca ccccatccct    180

ttcgtgccac tcccgtcccc acccccaccc cagtgtgtat aagctggcat ttcgccagct    240

tgtacgtagc ttgccactca gtgaaaataa taacattatt atgagaaagt ggacttaacc    300

gaaatggaac caactgacat tctatcgtgt tgtacataga atgatgaagg gttccactgt    360

tgttgtatgt cttaaattta tttaaaactt tttttaatcc agatgtagac tatattctaa    420

aaaataaaaa agcaaatgtg tcaactaaat tggacaagcg tctggtcctc attaatctgc    480

caatgaatgg tttcgtcatt aaataaaaat caatttaatt gatttactag c             531


<210>  10534
<211>  41
<212>  PRT
<213>  Homo sapiens

<400>  10534

Met Ala Pro Pro Pro His Pro Phe Arg Ala Thr Pro Val Pro Thr Pro 
1               5                   10                  15


Thr Pro Val Cys Ile Ser Trp His Phe Ala Ser Leu Tyr Val Ala Cys 
            20                  25                  30


His Ser Val Lys Ile Ile Thr Leu Leu 
        35                  40


<210>  10535
<211>  1500
<212>  DNA
<213>  Homo sapiens

<400>  10535
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggctgc gtggaggagg gggccacgtg    720

tgagagagaa gaaaatggtg gccggagatg ggagggccca aggaacctcc tgggaggggg    780

cctgcattct atgttggtgg gaatgggact gggctgacgc cctgcattca gcctgtgcct    840

ttcctggggt ttcttttctg ttcttttcgg aggagagggc ccgagaaggg gccataccag    900

ggcgcggcgc tgggttgcca cacttgggaa agcagcccgg agctgggtgc tggggaaggc    960

ggggcgcgta gcctcccgcc gccctgcggt tgggccggtg gaggcccagg cgttgctagg   1020

attgcatcag ttttcctgtt tgcactattt ctttttgtaa cattggccct gtgtgaagta   1080

tttcgaatct cctccttgct ctgaaacttc agcgattcca ttgtgataag cgcacaaaca   1140

gcactgtctg tcggtaatcg gtactacttt attaatgatt ttctgttaca ctgtatagta   1200

gtcctatggc acccccaccc catccctttc gtgccactcc cgtccccacc cccaccccag   1260

tgtgtataag ctggcatttc gccagcttgt acgtagcttg ccactcagtg aaaataataa   1320

cattattatg agaaagtgga cttaaccgaa atggaaccaa ctgacattct atcgtgttgt   1380

acatagaatg atgaagggtt ccactgttgt tgtatgtctt aaatttattt aaaacttttt   1440

ttaatccaga tgtagactat attctaaaaa ataaaaaagc aaatgtgtca actaaattgg   1500


<210>  10536
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  10536

Met Pro Gly His Pro Leu Leu Arg Lys Ser Pro Arg Met Glu Leu Tyr 
1               5                   10                  15


Leu Leu Pro Ala Pro Leu Pro Arg Arg Leu Ile Ile Asn Pro Gly Ser 
            20                  25                  30


Cys Phe Pro Ala Ala Ala Thr Pro Asp Ser Gly Leu Arg Gly Ser Leu 
        35                  40                  45


Cys Asn Gln Gly Thr Cys Ile Leu Val Ile Pro Arg Gly Glu Arg Ala 
    50                  55                  60


Gln Gly Pro Pro Ser Pro His Met Pro Ala Pro Pro Ser Ser Arg Ser 
65                  70                  75                  80


Gly Arg Arg Arg Leu Phe Asp Pro Arg Cys Ala Arg Pro Ser Ser Ser 
                85                  90                  95


Gly Leu Pro Arg Ala Trp Cys Trp Arg Gly Pro Ala Ala Pro Ile Pro 
            100                 105                 110


Pro Pro Leu Leu Cys Pro Ala Leu Pro Trp Pro Ala Pro Ala Pro Ser 
        115                 120                 125


Leu Ser Pro Gly Ile Arg Arg Glu Ala Glu Leu Ala Arg Arg Ala Pro 
    130                 135                 140


Pro Pro Leu 
145


<210>  10537
<211>  2657
<212>  DNA
<213>  Homo sapiens

<400>  10537
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggtggc cctgagcgcc ggcgacacct    720

ttcctggact ataaattgag cacctgggat gggtaggggg ccaacgcagt caccgccgtc    780

cgcagtcaca gtccagccac tgaccgcagc agcgcccttg cgtagcagcc gcttgcagcg    840

agaacactga attgccaacg agcaggagag tctcaaggcg caagaggagg ccagggctcg    900

acccacagag caccctcagc catcgcgagt ttccgggcgc caaagccagg agaagccgcc    960

catcccgcag ggccggtctg ccagcgagac gagagttggc gagggcggag gagtgccggg   1020

aatcccgcca caccggctat agccaggccc ccagcgcggg ccttggagag cgcgtgaagg   1080

cgggcatccc cttgacccgg ccgaccatcc ccgtgcccct gcgtccctgc gctccaacgt   1140

ccgcgcggcc accatgatgc aaatctgcga cacctacaac cagaagcact cgctctttaa   1200

cgccatgaat cgcttcattg gcgccgtgaa caacatggac cagacggtga tggtgcccag   1260

cttgctgcgc gacgtgcccc tggctgaccc cgggttagac aacgatgttg gcgtggaggt   1320

aggcggcagt ggcggctgcc tggaggagcg cacgccccca gtccccgact cgggaagcgc   1380

caatggcagc tttttcgcgc cctctcggga catgtacagc cactacgtgc ttctcaagtc   1440

catccgcaac gacatcgagt ggggggtcct gcaccagccg cctccaccgg ctgggagcga   1500

ggagggcagt gcctggaagt ccaaggacat cctggtggac ctgggccact tggagggtgc   1560

ggacgccggc gaagaagacc tggaacagca gttccactac cacctgcgcg ggctgcacac   1620

tgtgctctcg aaactcacgc gcaaagccaa catcctcact aacagataca agcaggagat   1680

cggcttcggc aattggggcc actgaggcgt ggcgcccgtg gctgcccagc accttcttcg   1740

acccatctca ccctctctca ttcctcaaag cttttttttt ttttcctggc tggggggcgg   1800

gaagggcaga ctgcaaactg gggggctgcg tacgtgcagg aggcgcggtg gggctgcgtg   1860

gaggaggggg ccacgtgtga gagagaagaa aatggtggcc ggagatggga gggcccaagg   1920

aacctcctgg gagggggcct gcattctatg ttggtgggaa tgggactggg ctgacgccct   1980

gcattcagcc tgtgcctttc ctggggtttc ttttctgttc ttttcggagg agagggcccg   2040

agaaggggcc ataccagggc gcggcgctgg gttgccacac ttgggaaagc agcccggagc   2100

tgggtgctgg ggaaggcggg gcgcgtagcc tcccgccgcc ctgcggttgg gccggtggag   2160

gcccaggcgt tgctaggatt gcatcagttt tcctgtttgc actatttctt tttgtaacat   2220

tggccctgtg tgaagtattt cgaatctcct ccttgctctg aaacttcagc gattccattg   2280

tgataagcgc acaaacagca ctgtctgtcg gtaatcggta ctactttatt aatgattttc   2340

tgttacactg tatagtagtc ctatggcacc cccaccccat ccctttcgtg ccactcccgt   2400

ccccaccccc accccagtgt gtataagctg gcatttcgcc agcttgtacg tagcttgcca   2460

ctcagtgaaa ataataacat tattatgaga aagtggactt aaccgaaatg gaaccaactg   2520

acattctatc gtgttgtaca tagaatgatg aagggttcca ctgttgttgt atgtcttaaa   2580

tttatttaaa acttttttta atccagatgt agactatatt ctaaaaaata aaaaagcaaa   2640

tgtgtcaact aaattgg                                                  2657


<210>  10538
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10538

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10539
<211>  2172
<212>  DNA
<213>  Homo sapiens

<400>  10539
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggtggc cctgagcgcc ggcgacacct    720

ttcctggact ataaattgag cacctgggat gggtaggggg ccaacgcagt caccgccgtc    780

cgcagtcaca gtccagccat gaccccgggt tagacaacga tgttggcgtg gaggtaggcg    840

gcagtggcgg ctgcctggag gagcgcacgc ccccagtccc cgactcggga agcgccaatg    900

gcagcttttt cgcgccctct cgggacatgt acagccacta cgtgcttctc aagtccatcc    960

gcaacgacat cgagtggggg gtcctgcacc agccgcctcc accggctggg agcgaggagg   1020

gcagtgcctg gaagtccaag gacatcctgg tggacctggg ccacttggag ggtgcggacg   1080

ccggcgaaga agacctggaa cagcagttcc actaccacct gcgcgggctg cacactgtgc   1140

tctcgaaact cacgcgcaaa gccaacatcc tcactaacag atacaagcag gagatcggct   1200

tcggcaattg gggccactga ggcgtggcgc ccgtggctgc ccagcacctt cttcgaccca   1260

tctcaccctc tctcattcct caaagctttt tttttttttc ctggctgggg ggcgggaagg   1320

gcagactgca aactgggggg ctgcgtacgt gcaggaggcg cggtggggct gcgtggagga   1380

gggggccacg tgtgagagag aagaaaatgg tggccggaga tgggagggcc caaggaacct   1440

cctgggaggg ggcctgcatt ctatgttggt gggaatggga ctgggctgac gccctgcatt   1500

cagcctgtgc ctttcctggg gtttcttttc tgttcttttc ggaggagagg gcccgagaag   1560

gggccatacc agggcgcggc gctgggttgc cacacttggg aaagcagccc ggagctgggt   1620

gctggggaag gcggggcgcg tagcctcccg ccgccctgcg gttgggccgg tggaggccca   1680

ggcgttgcta ggattgcatc agttttcctg tttgcactat ttctttttgt aacattggcc   1740

ctgtgtgaag tatttcgaat ctcctccttg ctctgaaact tcagcgattc cattgtgata   1800

agcgcacaaa cagcactgtc tgtcggtaat cggtactact ttattaatga ttttctgtta   1860

cactgtatag tagtcctatg gcacccccac cccatccctt tcgtgccact cccgtcccca   1920

cccccacccc agtgtgtata agctggcatt tcgccagctt gtacgtagct tgccactcag   1980

tgaaaataat aacattatta tgagaaagtg gacttaaccg aaatggaacc aactgacatt   2040

ctatcgtgtt gtacatagaa tgatgaaggg ttccactgtt gttgtatgtc ttaaatttat   2100

ttaaaacttt ttttaatcca gatgtagact atattctaaa aaataaaaaa gcaaatgtgt   2160

caactaaatt gg                                                       2172


<210>  10540
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  10540

Met Ala Ala Phe Ser Arg Pro Leu Gly Thr Cys Thr Ala Thr Thr Cys 
1               5                   10                  15


Phe Ser Ser Pro Ser Ala Thr Thr Ser Ser Gly Gly Ser Cys Thr Ser 
            20                  25                  30


Arg Leu His Arg Leu Gly Ala Arg Arg Ala Val Pro Gly Ser Pro Arg 
        35                  40                  45


Thr Ser Trp Trp Thr Trp Ala Thr Trp Arg Val Arg Thr Pro Ala Lys 
    50                  55                  60


Lys Thr Trp Asn Ser Ser Ser Thr Thr Thr Cys Ala Gly Cys Thr Leu 
65                  70                  75                  80


Cys Ser Arg Asn Ser Arg Ala Lys Pro Thr Ser Ser Leu Thr Asp Thr 
                85                  90                  95


Ser Arg Arg Ser Ala Ser Ala Ile Gly Ala Thr Glu Ala Trp Arg Pro 
            100                 105                 110


Trp Leu Pro Ser Thr Phe Phe Asp Pro Ser His Pro Leu Ser Phe Leu 
        115                 120                 125


Lys Ala Phe Phe Phe Phe Pro Gly Trp Gly Ala Gly Arg Ala Asp Cys 
    130                 135                 140


Lys Leu Gly Gly Cys Val Arg Ala Gly Gly Ala Val Gly Leu Arg Gly 
145                 150                 155                 160


Gly Gly Gly His Val 
                165


<210>  10541
<211>  2250
<212>  DNA
<213>  Homo sapiens

<400>  10541
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggtggc cctgagcgcc ggcgacacct    720

ttcctggact ataaattgag cacctgggat gggtaggggg ccaacgcagt caccgccgtc    780

cgcagtcaca gtccagccat gaccccgggt tagacaacga tgttggcgtg gaggtaggcg    840

gcagtggcgg ctgcctggag gagcgcacgc ccccagtccc cgactcggga agcgccaatg    900

gcagcttttt cgcgccctct cgggacatgt acagccacta cgtgcttctc aagtccatcc    960

gcaacgacat cgagtggggg gtcctgcacc agccgcctcc accggctggg agcgaggagg   1020

gcagtgcctg gaagtccaag gacatcctgg tggacctggg ccacttggag ggtgcggacg   1080

ccggcgaaga agacctggaa cagcagttcc actaccacct gcgcgggctg cacactgtgc   1140

tctcgaaact cacgcgcaaa gccaacatcc tcactaacag atacaagcag gagatcggct   1200

tcggcaattg gggccactga ggcgtggcgc ccgtggctgc ccagcacctt cttcgaccca   1260

tctcaccctc tctcattcct caaagctttt tttttttttc ctggctgggg ggcgggaagg   1320

gcagactgca aactgggggg ctgcgtacgt gcaggaggcg cggtggggct gcgtggagga   1380

gggggccacg tgtgagagag aagaaaatgg tggccggaga tgggagggcc caaggaacct   1440

cctgggaggg ggcctgcatt ctatgttggt gggaatggga ctgggctgac gccctgcatt   1500

cagcctgtgc ctttcctggg gtttcttttc tgttcttttc ggaggagagg gcccgagaag   1560

gggccatacc agggcgcggc gctgggttgc cacacttggg aaagcagccc ggagctgggt   1620

gctggggaag gcggggcgcg tagcctcccg ccgccctgcg gttgggccgg tggaggccca   1680

ggcgttgcta ggattgcatc agttttcctg tttgcactat ttctttttgt aacattggcc   1740

ctgtgtgaag tatttcgaat ctcctccttg ctctgaaact tcagcgattc cattgtgata   1800

agcgcacaaa cagcactgtc tgtcggtaat cggtactact ttattaatga ttttctgtta   1860

cactgtatag tagtcctatg gcacccccac cccatccctt tcgtgccact cccgtcccca   1920

cccccacccc agtgtgtata agctggcatt tcgccagctt gtacgtagct tgccactcag   1980

tgaaaataat aacattatta tgagaaagtg gacttaaccg aaatggaacc aactgacatt   2040

ctatcgtgtt gtacatagaa tgatgaaggg ttccactgtt gttgtatgtc ttaaatttat   2100

ttaaaacttt ttttaatcca gatgtagact atattctaaa aaataaaaaa gcaaatgtgt   2160

caactaaatt ggacaagcgt ctggtcctca ttaatctgcc aatgaatggt ttcgtcatta   2220

aataaaaatc aatttaattg atttactagc                                    2250


<210>  10542
<211>  165
<212>  PRT
<213>  Homo sapiens

<400>  10542

Met Ala Ala Phe Ser Arg Pro Leu Gly Thr Cys Thr Ala Thr Thr Cys 
1               5                   10                  15


Phe Ser Ser Pro Ser Ala Thr Thr Ser Ser Gly Gly Ser Cys Thr Ser 
            20                  25                  30


Arg Leu His Arg Leu Gly Ala Arg Arg Ala Val Pro Gly Ser Pro Arg 
        35                  40                  45


Thr Ser Trp Trp Thr Trp Ala Thr Trp Arg Val Arg Thr Pro Ala Lys 
    50                  55                  60


Lys Thr Trp Asn Ser Ser Ser Thr Thr Thr Cys Ala Gly Cys Thr Leu 
65                  70                  75                  80


Cys Ser Arg Asn Ser Arg Ala Lys Pro Thr Ser Ser Leu Thr Asp Thr 
                85                  90                  95


Ser Arg Arg Ser Ala Ser Ala Ile Gly Ala Thr Glu Ala Trp Arg Pro 
            100                 105                 110


Trp Leu Pro Ser Thr Phe Phe Asp Pro Ser His Pro Leu Ser Phe Leu 
        115                 120                 125


Lys Ala Phe Phe Phe Phe Pro Gly Trp Gly Ala Gly Arg Ala Asp Cys 
    130                 135                 140


Lys Leu Gly Gly Cys Val Arg Ala Gly Gly Ala Val Gly Leu Arg Gly 
145                 150                 155                 160


Gly Gly Gly His Val 
                165


<210>  10543
<211>  1578
<212>  DNA
<213>  Homo sapiens

<400>  10543
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggctgc gtggaggagg gggccacgtg    720

tgagagagaa gaaaatggtg gccggagatg ggagggccca aggaacctcc tgggaggggg    780

cctgcattct atgttggtgg gaatgggact gggctgacgc cctgcattca gcctgtgcct    840

ttcctggggt ttcttttctg ttcttttcgg aggagagggc ccgagaaggg gccataccag    900

ggcgcggcgc tgggttgcca cacttgggaa agcagcccgg agctgggtgc tggggaaggc    960

ggggcgcgta gcctcccgcc gccctgcggt tgggccggtg gaggcccagg cgttgctagg   1020

attgcatcag ttttcctgtt tgcactattt ctttttgtaa cattggccct gtgtgaagta   1080

tttcgaatct cctccttgct ctgaaacttc agcgattcca ttgtgataag cgcacaaaca   1140

gcactgtctg tcggtaatcg gtactacttt attaatgatt ttctgttaca ctgtatagta   1200

gtcctatggc acccccaccc catccctttc gtgccactcc cgtccccacc cccaccccag   1260

tgtgtataag ctggcatttc gccagcttgt acgtagcttg ccactcagtg aaaataataa   1320

cattattatg agaaagtgga cttaaccgaa atggaaccaa ctgacattct atcgtgttgt   1380

acatagaatg atgaagggtt ccactgttgt tgtatgtctt aaatttattt aaaacttttt   1440

ttaatccaga tgtagactat attctaaaaa ataaaaaagc aaatgtgtca actaaattgg   1500

acaagcgtct ggtcctcatt aatctgccaa tgaatggttt cgtcattaaa taaaaatcaa   1560

tttaattgat ttactagc                                                 1578


<210>  10544
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  10544

Met Pro Gly His Pro Leu Leu Arg Lys Ser Pro Arg Met Glu Leu Tyr 
1               5                   10                  15


Leu Leu Pro Ala Pro Leu Pro Arg Arg Leu Ile Ile Asn Pro Gly Ser 
            20                  25                  30


Cys Phe Pro Ala Ala Ala Thr Pro Asp Ser Gly Leu Arg Gly Ser Leu 
        35                  40                  45


Cys Asn Gln Gly Thr Cys Ile Leu Val Ile Pro Arg Gly Glu Arg Ala 
    50                  55                  60


Gln Gly Pro Pro Ser Pro His Met Pro Ala Pro Pro Ser Ser Arg Ser 
65                  70                  75                  80


Gly Arg Arg Arg Leu Phe Asp Pro Arg Cys Ala Arg Pro Ser Ser Ser 
                85                  90                  95


Gly Leu Pro Arg Ala Trp Cys Trp Arg Gly Pro Ala Ala Pro Ile Pro 
            100                 105                 110


Pro Pro Leu Leu Cys Pro Ala Leu Pro Trp Pro Ala Pro Ala Pro Ser 
        115                 120                 125


Leu Ser Pro Gly Ile Arg Arg Glu Ala Glu Leu Ala Arg Arg Ala Pro 
    130                 135                 140


Pro Pro Leu 
145


<210>  10545
<211>  2735
<212>  DNA
<213>  Homo sapiens

<400>  10545
gtgtgcccct cttcatcccc ggcaaccact gttaaaggaa agattgggaa agatcccacc     60

ccgccaggag ggaggcaaaa gcctctgacg ctcccctccc cccatagctg accaaggcca    120

gggccactgc gggagcaccg cgcgtccacg tgcacccagc atgcccggtc accctttatt    180

acgtaagagt cccaggatgg agttgtacct gctgccggcc cctcttcccc gacggctaat    240

aataaacccg ggttcctgtt tcccggccgc ggccactcca gattcggggc tgaggggctc    300

actctgcaac caaggcacgt gcattctggt catcccacgc ggggagcgcg cgcaaggccc    360

gcccagcccc cacatgccag ccccaccctc cagtcggtcc ggacgccgac gcctttttga    420

ccctcgctgt gcccggccct cctcatctgg cctgcccagg gcttggtgct ggcggggtcc    480

agctgctcca atccctcctc ctctgctctg ccctgccctg ccctggcctg ccccggcgcc    540

ctccctcagc ccgggtatca ggcgagaggc ggagctggcc cggcgcgccc cgcccccgct    600

gtagaaaggg ccgggcgagt gttactcgcg gtcatcccgg cctgggcctt ttatctcggt    660

gctgccgggg gaggcgggag gaggagacac caggggtggc cctgagcgcc ggcgacacct    720

ttcctggact ataaattgag cacctgggat gggtaggggg ccaacgcagt caccgccgtc    780

cgcagtcaca gtccagccac tgaccgcagc agcgcccttg cgtagcagcc gcttgcagcg    840

agaacactga attgccaacg agcaggagag tctcaaggcg caagaggagg ccagggctcg    900

acccacagag caccctcagc catcgcgagt ttccgggcgc caaagccagg agaagccgcc    960

catcccgcag ggccggtctg ccagcgagac gagagttggc gagggcggag gagtgccggg   1020

aatcccgcca caccggctat agccaggccc ccagcgcggg ccttggagag cgcgtgaagg   1080

cgggcatccc cttgacccgg ccgaccatcc ccgtgcccct gcgtccctgc gctccaacgt   1140

ccgcgcggcc accatgatgc aaatctgcga cacctacaac cagaagcact cgctctttaa   1200

cgccatgaat cgcttcattg gcgccgtgaa caacatggac cagacggtga tggtgcccag   1260

cttgctgcgc gacgtgcccc tggctgaccc cgggttagac aacgatgttg gcgtggaggt   1320

aggcggcagt ggcggctgcc tggaggagcg cacgccccca gtccccgact cgggaagcgc   1380

caatggcagc tttttcgcgc cctctcggga catgtacagc cactacgtgc ttctcaagtc   1440

catccgcaac gacatcgagt ggggggtcct gcaccagccg cctccaccgg ctgggagcga   1500

ggagggcagt gcctggaagt ccaaggacat cctggtggac ctgggccact tggagggtgc   1560

ggacgccggc gaagaagacc tggaacagca gttccactac cacctgcgcg ggctgcacac   1620

tgtgctctcg aaactcacgc gcaaagccaa catcctcact aacagataca agcaggagat   1680

cggcttcggc aattggggcc actgaggcgt ggcgcccgtg gctgcccagc accttcttcg   1740

acccatctca ccctctctca ttcctcaaag cttttttttt ttttcctggc tggggggcgg   1800

gaagggcaga ctgcaaactg gggggctgcg tacgtgcagg aggcgcggtg gggctgcgtg   1860

gaggaggggg ccacgtgtga gagagaagaa aatggtggcc ggagatggga gggcccaagg   1920

aacctcctgg gagggggcct gcattctatg ttggtgggaa tgggactggg ctgacgccct   1980

gcattcagcc tgtgcctttc ctggggtttc ttttctgttc ttttcggagg agagggcccg   2040

agaaggggcc ataccagggc gcggcgctgg gttgccacac ttgggaaagc agcccggagc   2100

tgggtgctgg ggaaggcggg gcgcgtagcc tcccgccgcc ctgcggttgg gccggtggag   2160

gcccaggcgt tgctaggatt gcatcagttt tcctgtttgc actatttctt tttgtaacat   2220

tggccctgtg tgaagtattt cgaatctcct ccttgctctg aaacttcagc gattccattg   2280

tgataagcgc acaaacagca ctgtctgtcg gtaatcggta ctactttatt aatgattttc   2340

tgttacactg tatagtagtc ctatggcacc cccaccccat ccctttcgtg ccactcccgt   2400

ccccaccccc accccagtgt gtataagctg gcatttcgcc agcttgtacg tagcttgcca   2460

ctcagtgaaa ataataacat tattatgaga aagtggactt aaccgaaatg gaaccaactg   2520

acattctatc gtgttgtaca tagaatgatg aagggttcca ctgttgttgt atgtcttaaa   2580

tttatttaaa acttttttta atccagatgt agactatatt ctaaaaaata aaaaagcaaa   2640

tgtgtcaact aaattggaca agcgtctggt cctcattaat ctgccaatga atggtttcgt   2700

cattaaataa aaatcaattt aattgattta ctagc                              2735


<210>  10546
<211>  183
<212>  PRT
<213>  Homo sapiens

<400>  10546

Met Met Gln Ile Cys Asp Thr Tyr Asn Gln Lys His Ser Leu Phe Asn 
1               5                   10                  15


Ala Met Asn Arg Phe Ile Gly Ala Val Asn Asn Met Asp Gln Thr Val 
            20                  25                  30


Met Val Pro Ser Leu Leu Arg Asp Val Pro Leu Ala Asp Pro Gly Leu 
        35                  40                  45


Asp Asn Asp Val Gly Val Glu Val Gly Gly Ser Gly Gly Cys Leu Glu 
    50                  55                  60


Glu Arg Thr Pro Pro Val Pro Asp Ser Gly Ser Ala Asn Gly Ser Phe 
65                  70                  75                  80


Phe Ala Pro Ser Arg Asp Met Tyr Ser His Tyr Val Leu Leu Lys Ser 
                85                  90                  95


Ile Arg Asn Asp Ile Glu Trp Gly Val Leu His Gln Pro Pro Pro Pro 
            100                 105                 110


Ala Gly Ser Glu Glu Gly Ser Ala Trp Lys Ser Lys Asp Ile Leu Val 
        115                 120                 125


Asp Leu Gly His Leu Glu Gly Ala Asp Ala Gly Glu Glu Asp Leu Glu 
    130                 135                 140


Gln Gln Phe His Tyr His Leu Arg Gly Leu His Thr Val Leu Ser Lys 
145                 150                 155                 160


Leu Thr Arg Lys Ala Asn Ile Leu Thr Asn Arg Tyr Lys Gln Glu Ile 
                165                 170                 175


Gly Phe Gly Asn Trp Gly His 
            180


<210>  10547
<211>  1231
<212>  DNA
<213>  Homo sapiens

<400>  10547
gagaaggggg tgcgcgcggg caagggcgcc aggcccccta gcagggtgaa taatctaatc     60

tgttctttcg tctccgtgta tcaaacaggc cagggctcga cccacagagc accctcagcc    120

atcgcgagtt tccgggcgcc aaagccagga gaagccgccc atcccgcagg gccggtctgc    180

cagcgagacg agagttggcg agggcggagg agtgccggga atcccgccac accggctata    240

gccaggcccc cagcgcgggc cttggagagc gcgtgaaggc gggcatcccc ttgacccggc    300

cgaccatccc cgtgcccctg cgtccctgcg ctccaacgtc cgcgcggcca ccatgatgca    360

aatctgcgac acctacaacc agaagcactc gctctttaac gccatgaatc gcttcattgg    420

cgccgtgaac aacatggacc agacggtgat ggtgcccagc ttgctgcgcg acgtgcccct    480

ggctgacccc gggttagaca acgatgttgg cgtggaggta ggcggcagtg gcggctgcct    540

ggaggagcgc acgcccccag tccccgactc gggaagcgcc aatggcagct ttttcgcgcc    600

ctctcgggac atgtacagcc actacgtgct tctcaagtcc atccgcaacg acatcgagtg    660

gggggtcctg caccagccgc ctccaccggc tgggagcgag gagggcagtg cctggaagtc    720

caaggacatc ctggtggacc tgggccactt ggagggtgcg gacgccggcg aagaagacct    780

ggaacagcag ttccactacc acctgcgcgg gctgcacact gtgctctcga aactcacgcg    840

caaagccaac atcctcacta acagatacaa gcaggagatc ggcttcggca attggggcca    900

ctgaggcgtg gcgcccgtgg ctgcccagca ccttcttcga cccatctcac cctctctcat    960

tcctcaaagc tttttttttt tttcctggct gtgtgtataa gctggcattt cgccagcttg   1020

tacgtagctt gccactcagt gaaaataata acattattat gagaaagtgg acttaaccga   1080

aatggaacca actgacattc tatcgtgttg tacatagaat gatgaagggt tccactgttg   1140

ttgtatgtct taaatttatt taaaactttt tttaatccag atgtagacta tattctaaaa   1200

aataaaaaag caaatgtgtc aactaaattg g                                  1231


<210>  10548
<211>  164
<212>  PRT
<213>  Homo sapiens

<400>  10548

Met Ala Ala Phe Ser Arg Pro Leu Gly Thr Cys Thr Ala Thr Thr Cys 
1               5                   10                  15


Phe Ser Ser Pro Ser Ala Thr Thr Ser Ser Gly Gly Ser Cys Thr Ser 
            20                  25                  30


Arg Leu His Arg Leu Gly Ala Arg Arg Ala Val Pro Gly Ser Pro Arg 
        35                  40                  45


Thr Ser Trp Trp Thr Trp Ala Thr Trp Arg Val Arg Thr Pro Ala Lys 
    50                  55                  60


Lys Thr Trp Asn Ser Ser Ser Thr Thr Thr Cys Ala Gly Cys Thr Leu 
65                  70                  75                  80


Cys Ser Arg Asn Ser Arg Ala Lys Pro Thr Ser Ser Leu Thr Asp Thr 
                85                  90                  95


Ser Arg Arg Ser Ala Ser Ala Ile Gly Ala Thr Glu Ala Trp Arg Pro 
            100                 105                 110


Trp Leu Pro Ser Thr Phe Phe Asp Pro Ser His Pro Leu Ser Phe Leu 
        115                 120                 125


Lys Ala Phe Phe Phe Phe Pro Gly Cys Val Tyr Lys Leu Ala Phe Arg 
    130                 135                 140


Gln Leu Val Arg Ser Leu Pro Leu Ser Glu Asn Asn Asn Ile Ile Met 
145                 150                 155                 160


Arg Lys Trp Thr 



<210>  10549
<211>  530
<212>  DNA
<213>  Homo sapiens

<400>  10549
ataatgacaa agaacatgag tgagactatg taaataggat tgcttatgga taaatccaca     60

tccttataaa tgtcaaagga cagctcactg tgaggatgga cttgttgcga ggaatgataa    120

aattattgca aatttctttc aagggaggag cttccacaga tctgggcttc ctgcagataa    180

aagaggcttt ataatcttca aacgaagcat gaaattttga gctgaaagag gccgtgtagt    240

gcaaatgaag atgggaatgg ttgggatggt agaccaatta caaggagctt gaacgttctt    300

ggtcagcatc tctcggacag cgggtacttc tggtggccac agagggtctt ttcatcacca    360

atcttccatt ccagctgaga tgaggtcttt tattttaacc tgaaaataaa agccctttcc    420

ctgaagacag tacctgccat catgttaatt tcttcaaaaa ggaaagaaga acaaaaagga    480

aagacttaca gggtcttggg aagattataa aactcattaa aagttcattt               530


<210>  10550
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  10550

Met Asp Leu Leu Arg Gly Met Ile Lys Leu Leu Gln Ile Ser Phe Lys 
1               5                   10                  15


Gly Gly Ala Ser Thr Asp Leu Gly Phe Leu Gln Ile Lys Glu Ala Leu 
            20                  25                  30


<210>  10551
<211>  766
<212>  DNA
<213>  Homo sapiens

<400>  10551
gccatcatgt aagaagagcc tttcacctcc cgccgtgatt ctgaggcttc cccagccacg     60

tggaactgtt ccacttccca caacacctct gccaccaacc aattgagggt cttcaggaga    120

agtgttctta tctgtgcaat agagcctgcc agaaggggca cctggcaacc ctcttcagag    180

gcttgatcct gtgctgcaga aacctatgga cctgctcaac ctgtgcactg gaattccagg    240

gatagactga gctgtcccta ggaggctggg agcattctcc agcagagacc agcaactgcc    300

tcctgcctgg agaatctgga aggaggaagg gcggctggaa tcacctgtga tgactccagt    360

gtgtcagaga agacaggaag accaagaaac agccaaggag aggggctgag gaatgagaga    420

tggaggagac aacagattgt ccttcccatt gccaaacctt aggccgggcc tgaggggatc    480

agactgggca attgaatcct caaaggttcc tggaaggact acttaggaat tgaatgtgct    540

gagacttcct ctcaaaggag cccctccttc ttaaatgaat ccaggagaga agttctgaag    600

actgtggtct atgctaaagg aatgcagata tttataaatg gtcatctgca ttgaatgaac    660

caagtccaaa tgacaatcaa ggagaactgt aaacatagga aaagagggct gaacccatgc    720

ttccagggaa ggaagaagag agagagaaag agaagagaag agagag                   766


<210>  10552
<211>  37
<212>  PRT
<213>  Homo sapiens

<400>  10552

Met Arg Asp Gly Gly Asp Asn Arg Leu Ser Phe Pro Leu Pro Asn Leu 
1               5                   10                  15


Arg Pro Gly Leu Arg Gly Ser Asp Trp Ala Ile Glu Ser Ser Lys Val 
            20                  25                  30


Pro Gly Arg Thr Thr 
        35


<210>  10553
<211>  2228
<212>  DNA
<213>  Homo sapiens

<400>  10553
attcaatctg tgaggtggat gcgtgttgga aggacccctt ttggtttctt tttgctcaga     60

gctttctttt aataaattcc gctctcctca cctttcaatg tgtccgtatg cctaattttt    120

cctggtcctg tgacaagaac ctgattttag ctgaactaag gagcgaaaga tcctggatca    180

ttttggtgac ccatactggt acatgaggaa agctcctatt ccagattctc agagtataga    240

ttctgactgg attaccctgg tccttgaagt atacctagga gatggaataa cattgtataa    300

gcatccacgt tgtcattaag aggaaagagt ttccattaaa acagcaggtc acaaaaccct    360

cctgtgagag gaaccctctg tggaagaaca gaatatgtca ccccaaaata tgaagaattg    420

ttgagctgaa gatgattaag aagaagcgga tgcaggaaag ctctctgctc tccctctatt    480

tgcttaaaag caggataaac acttacaaag actaaagacg ccacaatcaa gaactcagaa    540

gggtagaaga aaaagatagt ttcccttccc tacacaggtg ttgatccctt cataaatatt    600

atgcatgcta agccctatct caaggtctac atccaggaga acccaacctg caacattaag    660

ttactgactg tgcaagaacc ctttgatcac gtaccttaca gaccaagata agtgaggatg    720

cccatgtata acctgctgtc tttctggtct cttatgtttt tgtaccagaa agggacaact    780

ttttgggtaa ccataggtct ctagtatatc tgtgattaca ataaagattt ttgatatacc    840

aaaactgatg aaccaaaatt ccactgaaat agcgagtaaa tggagttctt ttatcctttg    900

cagtatacca gggtgaactt tttacatgat ttcttgctcc aaagggagaa gtgttatgac    960

aaagtacatt taaggaccct aactgatcac agaaaaaata ttaatggcat tgggaaaaaa   1020

atgcagacta atgaatccac tactaaattt tatctatctt gtagctctaa aattgcactg   1080

tttagaatac actatggtag ccactagaca tatggctact tgaacttgaa ttggttaaaa   1140

tcaaaattaa gaatttaatt tctcactcac attagccaca tttcaagtgc tcaacagaca   1200

catgtggcta gtgtctacca tattggacag catagattta aagcacattt ccatcattgc   1260

aacactgcaa tatggaggat gtatcctcaa tacattgata ttgccccctc aaaattcata   1320

acccctagat atcttatctc tgtatgtgag gatagtgtat taacttgcac ctggactgag   1380

atagataaat gcttatctcc agagatgtct gaaagtctgg tactgaccct tgtctaagat   1440

aaggatggaa tgtgctggtt aatgatttat actgtgctat acaaagtcca aaattccttt   1500

ggaggtatcc tctgctggct tgtctacatt gtttaaggat ggataggttg atggtttgca   1560

cctgctttaa tcatttacac attctgattt tatttgtgat cagtggagga taaaaccttc   1620

aataaacttg tgtcttagct tccttgatat taagatatct tgcacatatc ttagattttt   1680

ataatctgaa tgcaaagcac atcctttgca attgagaaag gactctgtga gctgctcctg   1740

gatatgtgaa acccctcagt gactgaccgt attttctttc ttctgctgta cttgccctta   1800

ttaaagcctt acatgtgaag taagtccttt caattgtctg actccgggtg attgttatac   1860

cctttgatat agtttggata tttgtgcctt ccaaatctca tgttgaaatg cgatccccta   1920

tgttggaggt ggagcctagt aggaggtgtt agggtcacgg gaatggatcc ctgatgaatg   1980

gcttggtaca cagtaatgag tgagtttgtg ctttattagt tactgtgaga tttacttggt   2040

aaaaagagcc tggcaactcc tccctctccc ttgctccctc tcttgccatg tgacatgctt   2100

gctccagctg caccttttgc cacaattgta agctttgtga gtccctcaac agaagctgag   2160

caaatgctgg caccatgctt cttgtacagc ctacagaact gtgaaccaaa taaaactttt   2220

atttttat                                                            2228


<210>  10554
<211>  38
<212>  PRT
<213>  Homo sapiens

<400>  10554

Met Arg Lys Ala Pro Ile Pro Asp Ser Gln Ser Ile Asp Ser Asp Trp 
1               5                   10                  15


Ile Thr Leu Val Leu Glu Val Tyr Leu Gly Asp Gly Ile Thr Leu Tyr 
            20                  25                  30


Lys His Pro Arg Cys His 
        35


<210>  10555
<211>  500
<212>  DNA
<213>  Homo sapiens

<400>  10555
aatctgtgag gtggatgcgt gttggaagga ccccttttgg tttctttttg ctcagagctt     60

tcttttaata aattccgctc tcctcacctt tcaatgtgtc cgtatgccta atttttcctg    120

gtcctgtgac aagaacctga ttttagctga actaaggagc gaaagatcct ggatcatttt    180

ggtgacccat actggtacat gaggaaagag ttcagtacag actgacacaa gattatctta    240

gctcctattc cagattctca gagtatagat tctgactgga ttaccctggt ccttgaagta    300

tacctaggag atggaataac attgtataag catccacgtt gtcattaaga ggaaagagtt    360

tccattaaaa cagcaggtca caaaaccctc ctgtgagagg aaccctctgt ggaagaacag    420

aatatgtcac cccaaaatat gaagaattgt tgagctgaag atgattaaga agaagcggat    480

gcaggaaagc tctctgctct                                                500


<210>  10556
<211>  32
<212>  PRT
<213>  Homo sapiens

<400>  10556

Met Pro Asn Phe Ser Trp Ser Cys Asp Lys Asn Leu Ile Leu Ala Glu 
1               5                   10                  15


Leu Arg Ser Glu Arg Ser Trp Ile Ile Leu Val Thr His Thr Gly Thr 
            20                  25                  30


<210>  10557
<211>  755
<212>  DNA
<213>  Homo sapiens

<400>  10557
agggttggcc ttgcgttcgc ctgagcaagg gagtagacag cacagcggca gcggagggag     60

tctatgcgag ctggacagca gtgggaggtt tgtgaggctc gcactggccg cagaccctcg    120

ggctcgatcg cccgggagcc aggactcggc gacgcgaggc tgccgggcta cccggccgag    180

gcttcggggg cgcaaactaa tgggactggc tcgctcggca gcatctcccc gctcttctaa    240

gtacactgag cagggcccgc gctgaagtag aagctgtccg ggggcgcgta gcccggagtc    300

ccagtgtggc ccggaggaac ggagcccgtg ccagggcggc ccagtcggga gcccggggac    360

cgagcttgtg ctgtggggaa acccccactt cttccaaggg acagcgatcc cgggacggtc    420

gaggcgtcgg ggcggtcacc gagacctctg cgggaagacc ccgtcgggga gagggcgcgc    480

agccccgaag cgtctcggga agtcgagcgg aatcgggcgg gatcacccgg gggcgcagag    540

cccccgtcgc gcctcgtgcg gcagcggaga gcccaggaga acgagccctc gggggccgaa    600

gcccatgccc ggcagaagca gggcggccct atgagtacta caagctgtac ctggtgcggc    660

ctgagcaggc agctgcctgt agcacagttc tcgaccccaa cgtgttggtc acctgcaata    720

ggccagagca ggaaatacgc tttaccatca agttc                               755


<210>  10558
<211>  58
<212>  PRT
<213>  Homo sapiens

<400>  10558

Met Arg Ala Gly Gln Gln Trp Glu Val Cys Glu Ala Arg Thr Gly Arg 
1               5                   10                  15


Arg Pro Ser Gly Ser Ile Ala Arg Glu Pro Gly Leu Gly Asp Ala Arg 
            20                  25                  30


Leu Pro Gly Tyr Pro Ala Glu Ala Ser Gly Ala Gln Thr Asn Gly Thr 
        35                  40                  45


Gly Ser Leu Gly Ser Ile Ser Pro Leu Phe 
    50                  55


<210>  10559
<211>  3261
<212>  DNA
<213>  Homo sapiens

<400>  10559
agggttggcc ttgcgttcgc ctgagcaagg gagtagacag cacagcggca gcggagggag     60

tctatgcgag ctggacagca gtgggaggtt tgtgaggctc gcactggccg cagaccctcg    120

ggctcgatcg cccgggagcc aggactcggc gacgcgaggc tgccgggcta cccggccgag    180

gcttcggggg cgcaaactaa tgggactggc tcgctcggca gcatctcccc gctcttctaa    240

gtacactgag cagggcccgc gctgaagtag aagctgtccg ggggcgcgta gcccggagtc    300

ccagtgtggc ccggaggaac ggagcccgtg ccagggcggc ccagtcggga gcccggggac    360

cgagcttgtg ctgtggggaa acccccactt cttccaaggg acagcgatcc cgggacggtc    420

gaggcgtcgg ggcggtcacc gagacctctg cgggaagacc ccgtcgggga gagggcgcgc    480

agccccgaag cgtctcggga agtcgagcgg aatcgggcgg gatcacccgg gggcgcagag    540

cccccgtcgc gcctcgtgcg gcagcggaga gcccaggaga acgagccctc gggggccgaa    600

gcccatgccc gggttggggg cggctgccca gtgagtcctc ctggccggcc gggcggagaa    660

gagcgacacc gaagccggcg ggaggggagc acttcaaggc cggcggctgc ggaggatggg    720

cgcctgagcg gctccgagcg cagcgcggca gaggaaggcg aggcgagctt tggtgaggag    780

gcgccaaggg atcccgaagt gcagtctgcc cccgggaaga tggctcggcc tgggcagcgt    840

tggctcggca agtggcttgt ggcgatggtc gtgtgggcgc tgtgccggct cgccacaccg    900

ctggccaaga acctggagcc cgtatcctgg agctccctca accccaagtt cctgagtggg    960

aagggcttgg tgatctatcc gaaaattgga gacaagctgg acatcatctg cccccgagca   1020

gaagcagggc ggccctatga gtactacaag ctgtacctgg tgcggcctga gcaggcagct   1080

gcctgtagca cagttctcga ccccaacgtg ttggtcacct gcaataggcc agagcaggaa   1140

atacgcttta ccatcaagtt ccaggagttc agccccaact acatgggcct ggagttcaag   1200

aagcaccatg attactacat tacctcaaca tccaatggaa gcctggaggg gctggaaaac   1260

cgggagggcg gtgtgtgccg cacacgcacc atgaagatca tcatgaaggt tgggcaagat   1320

cccaatgctg tgacgcctga gcagctgact accagcaggc ccagcaagga ggcagacaac   1380

actgtcaaga tggccacaca ggcccctggt agtcggggct ccctgggtga ctctgatggc   1440

aagcatgaga ctgtgaacca ggaagagaag agtggcccag gtgcaagtgg gggcagcagc   1500

ggggaccctg atggcttctt caactccaag gtggcattgt tcgcggctgt cggtgccggt   1560

tgcgtcatct tcctgctcat catcatcttc ctgacggtcc tactactgaa gctacgcaag   1620

cggcaccgca agcacacaca gcagcgggcg gctgccctct cgctcagtac cctggccagt   1680

cccaaggggg gcagtggcac agcgggcacc gagcccagcg acatcatcat tcccttacgg   1740

actacagaga acaactactg cccccactat gagaaggtga gtggggacta cgggcaccct   1800

gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta caaggtctga   1860

gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac ctctcctttc   1920

gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt ttgtagtttc   1980

ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg gtgcttgtgc   2040

ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc tccgtggggg   2100

cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga gacagtcccc   2160

tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt ccgctatcat   2220

cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc atctgttttt   2280

tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga gcctggccca   2340

agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag gatgccattt   2400

cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc tgttcacgcc   2460

catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc ctgaccctcc   2520

tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac acacacacac   2580

acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc tgcctccctc   2640

actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag agctgctgca   2700

ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta tttgccctgc   2760

agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt ggcatccttt   2820

ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag accaggtggc   2880

ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca gctcctgctg   2940

ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg ctgggccagc   3000

ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac tgccacttga   3060

gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca caccatccac   3120

ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag ggagcagaac   3180

agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg ttgccatttg   3240

tgtaaatact agtctttttg g                                             3261


<210>  10560
<211>  346
<212>  PRT
<213>  Homo sapiens

<400>  10560

Met Ala Arg Pro Gly Gln Arg Trp Leu Gly Lys Trp Leu Val Ala Met 
1               5                   10                  15


Val Val Trp Ala Leu Cys Arg Leu Ala Thr Pro Leu Ala Lys Asn Leu 
            20                  25                  30


Glu Pro Val Ser Trp Ser Ser Leu Asn Pro Lys Phe Leu Ser Gly Lys 
        35                  40                  45


Gly Leu Val Ile Tyr Pro Lys Ile Gly Asp Lys Leu Asp Ile Ile Cys 
    50                  55                  60


Pro Arg Ala Glu Ala Gly Arg Pro Tyr Glu Tyr Tyr Lys Leu Tyr Leu 
65                  70                  75                  80


Val Arg Pro Glu Gln Ala Ala Ala Cys Ser Thr Val Leu Asp Pro Asn 
                85                  90                  95


Val Leu Val Thr Cys Asn Arg Pro Glu Gln Glu Ile Arg Phe Thr Ile 
            100                 105                 110


Lys Phe Gln Glu Phe Ser Pro Asn Tyr Met Gly Leu Glu Phe Lys Lys 
        115                 120                 125


His His Asp Tyr Tyr Ile Thr Ser Thr Ser Asn Gly Ser Leu Glu Gly 
    130                 135                 140


Leu Glu Asn Arg Glu Gly Gly Val Cys Arg Thr Arg Thr Met Lys Ile 
145                 150                 155                 160


Ile Met Lys Val Gly Gln Asp Pro Asn Ala Val Thr Pro Glu Gln Leu 
                165                 170                 175


Thr Thr Ser Arg Pro Ser Lys Glu Ala Asp Asn Thr Val Lys Met Ala 
            180                 185                 190


Thr Gln Ala Pro Gly Ser Arg Gly Ser Leu Gly Asp Ser Asp Gly Lys 
        195                 200                 205


His Glu Thr Val Asn Gln Glu Glu Lys Ser Gly Pro Gly Ala Ser Gly 
    210                 215                 220


Gly Ser Ser Gly Asp Pro Asp Gly Phe Phe Asn Ser Lys Val Ala Leu 
225                 230                 235                 240


Phe Ala Ala Val Gly Ala Gly Cys Val Ile Phe Leu Leu Ile Ile Ile 
                245                 250                 255


Phe Leu Thr Val Leu Leu Leu Lys Leu Arg Lys Arg His Arg Lys His 
            260                 265                 270


Thr Gln Gln Arg Ala Ala Ala Leu Ser Leu Ser Thr Leu Ala Ser Pro 
        275                 280                 285


Lys Gly Gly Ser Gly Thr Ala Gly Thr Glu Pro Ser Asp Ile Ile Ile 
    290                 295                 300


Pro Leu Arg Thr Thr Glu Asn Asn Tyr Cys Pro His Tyr Glu Lys Val 
305                 310                 315                 320


Ser Gly Asp Tyr Gly His Pro Val Tyr Ile Val Gln Glu Met Pro Pro 
                325                 330                 335


Gln Ser Pro Ala Asn Ile Tyr Tyr Lys Val 
            340                 345


<210>  10561
<211>  3326
<212>  DNA
<213>  Homo sapiens

<400>  10561
agggttggcc ttgcgttcgc ctgagcaagg gagtagacag cacagcggca gcggagggag     60

tctatgcgag ctggacagca gtgggaggtt tgtgaggctc gcactggccg cagaccctcg    120

ggctcgatcg cccgggagcc aggactcggc gacgcgaggc tgccgggcta cccggccgag    180

gcttcggggg cgcaaactaa tgggactggc tcgctcggca gcatctcccc gctcttctaa    240

gtacactgag cagggcccgc gctgaagtag aagctgtccg ggggcgcgta gcccggagtc    300

ccagtgtggc ccggaggaac ggagcccgtg ccagggcggc ccagtcggga gcccggggac    360

cgagcttgtg ctgtggggaa acccccactt cttccaaggg acagcgatcc cgggacggtc    420

gaggcgtcgg ggcggtcacc gagacctctg cgggaagacc ccgtcgggga gagggcgcgc    480

agccccgaag cgtctcggga agtcgagcgg aatcgggcgg gatcacccgg gggcgcagag    540

cccccgtcgc gcctcgtgcg gcagcggaga gcccaggaga acgagccctc gggggccgaa    600

gcccatgccc gggttggggg cggctgccca gtgagtcctc ctggccggcc gggcggagaa    660

gagcgacacc gaagccggcg ggaggggagc acttcaaggc cggcggctgc ggaggatggg    720

cgcctgagcg gctccgagcg cagcgcggca gaggaaggcg aggcgagctt tggtgaggag    780

gcgccaaggg atcccgaagt gcagtctgcc cccgggaaga tggctcggcc tgggcagcgt    840

tggctcggca agtggcttgt ggcgatggtc gtgtgggcgc tgtgccggct cgccacaccg    900

ctggccaaga acctggagcc cgtatcctgg agctccctca accccaagtt cctgagtggg    960

aagggcttgg tgatctatcc gaaaattgga gacaagctgg acatcatctg cccccgagca   1020

gaagcagggc ggccctatga gtactacaag ctgtacctgg tgcggcctga gcaggcagct   1080

gcctgtagca cagttctcga ccccaacgtg ttggtcacct gcaataggcc agagcaggaa   1140

atacgcttta ccatcaagtt ccaggagttc agccccaact acatgggcct ggagttcaag   1200

aagcaccatg attactacat tacctcaaca tccaatggaa gcctggaggg gctggaaaac   1260

cgggagggcg gtgtgtgccg cacacgcacc atgaagatca tcatgaaggt tgggcaagat   1320

cccaatgctg tgacgcctga gcagctgact accagcaggc ccagcaagga ggcagacaac   1380

actgtcaaga tggccacaca ggcccctggt agtcggggct ccctgggtga ctctgatggc   1440

aagcatgaga ctgtgaacca ggaagagaag agtggcccag gtgcaagtgg gggcagcagc   1500

ggggaccctg atggcttctt caactccaag gtggcattgt tcgcggctgt cggtgccggt   1560

tgcgtcatct tcctgctcat catcatcttc ctgacggtcc tactactgaa gctacgcaag   1620

cggcaccgca agcacacaca gcagcgggcg gctgccctct cgctcagtac cctggccagt   1680

cccaaggggg gcagtggcac agcgggcacc gagcccagcg acatcatcat tcccttacgg   1740

actacagaga acaactactg cccccactat gagaaggtga gtggggacta cgggcaccct   1800

gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta caaggtctga   1860

gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac ctctcctttc   1920

gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt ttgtagtttc   1980

ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg gtgcttgtgc   2040

ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc tccgtggggg   2100

cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga gacagtcccc   2160

tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt ccgctatcat   2220

cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc atctgttttt   2280

tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga gcctggccca   2340

agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag gatgccattt   2400

cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc tgttcacgcc   2460

catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc ctgaccctcc   2520

tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac acacacacac   2580

acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc tgcctccctc   2640

actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag agctgctgca   2700

ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta tttgccctgc   2760

agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt ggcatccttt   2820

ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag accaggtggc   2880

ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca gctcctgctg   2940

ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg ctgggccagc   3000

ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac tgccacttga   3060

gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca caccatccac   3120

ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag ggagcagaac   3180

agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg ttgccatttg   3240

tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat aaactctgaa   3300

ttattttctt gttgcttttt tcttag                                        3326


<210>  10562
<211>  346
<212>  PRT
<213>  Homo sapiens

<400>  10562

Met Ala Arg Pro Gly Gln Arg Trp Leu Gly Lys Trp Leu Val Ala Met 
1               5                   10                  15


Val Val Trp Ala Leu Cys Arg Leu Ala Thr Pro Leu Ala Lys Asn Leu 
            20                  25                  30


Glu Pro Val Ser Trp Ser Ser Leu Asn Pro Lys Phe Leu Ser Gly Lys 
        35                  40                  45


Gly Leu Val Ile Tyr Pro Lys Ile Gly Asp Lys Leu Asp Ile Ile Cys 
    50                  55                  60


Pro Arg Ala Glu Ala Gly Arg Pro Tyr Glu Tyr Tyr Lys Leu Tyr Leu 
65                  70                  75                  80


Val Arg Pro Glu Gln Ala Ala Ala Cys Ser Thr Val Leu Asp Pro Asn 
                85                  90                  95


Val Leu Val Thr Cys Asn Arg Pro Glu Gln Glu Ile Arg Phe Thr Ile 
            100                 105                 110


Lys Phe Gln Glu Phe Ser Pro Asn Tyr Met Gly Leu Glu Phe Lys Lys 
        115                 120                 125


His His Asp Tyr Tyr Ile Thr Ser Thr Ser Asn Gly Ser Leu Glu Gly 
    130                 135                 140


Leu Glu Asn Arg Glu Gly Gly Val Cys Arg Thr Arg Thr Met Lys Ile 
145                 150                 155                 160


Ile Met Lys Val Gly Gln Asp Pro Asn Ala Val Thr Pro Glu Gln Leu 
                165                 170                 175


Thr Thr Ser Arg Pro Ser Lys Glu Ala Asp Asn Thr Val Lys Met Ala 
            180                 185                 190


Thr Gln Ala Pro Gly Ser Arg Gly Ser Leu Gly Asp Ser Asp Gly Lys 
        195                 200                 205


His Glu Thr Val Asn Gln Glu Glu Lys Ser Gly Pro Gly Ala Ser Gly 
    210                 215                 220


Gly Ser Ser Gly Asp Pro Asp Gly Phe Phe Asn Ser Lys Val Ala Leu 
225                 230                 235                 240


Phe Ala Ala Val Gly Ala Gly Cys Val Ile Phe Leu Leu Ile Ile Ile 
                245                 250                 255


Phe Leu Thr Val Leu Leu Leu Lys Leu Arg Lys Arg His Arg Lys His 
            260                 265                 270


Thr Gln Gln Arg Ala Ala Ala Leu Ser Leu Ser Thr Leu Ala Ser Pro 
        275                 280                 285


Lys Gly Gly Ser Gly Thr Ala Gly Thr Glu Pro Ser Asp Ile Ile Ile 
    290                 295                 300


Pro Leu Arg Thr Thr Glu Asn Asn Tyr Cys Pro His Tyr Glu Lys Val 
305                 310                 315                 320


Ser Gly Asp Tyr Gly His Pro Val Tyr Ile Val Gln Glu Met Pro Pro 
                325                 330                 335


Gln Ser Pro Ala Asn Ile Tyr Tyr Lys Val 
            340                 345


<210>  10563
<211>  3374
<212>  DNA
<213>  Homo sapiens

<400>  10563
agggttggcc ttgcgttcgc ctgagcaagg gagtagacag cacagcggca gcggagggag     60

tctatgcgag ctggacagca gtgggaggtt tgtgaggctc gcactggccg cagaccctcg    120

ggctcgatcg cccgggagcc aggactcggc gacgcgaggc tgccgggcta cccggccgag    180

gcttcggggg cgcaaactaa tgggactggc tcgctcggca gcatctcccc gctcttctaa    240

gtacactgag cagggcccgc gctgaagtag aagctgtccg ggggcgcgta gcccggagtc    300

ccagtgtggc ccggaggaac ggagcccgtg ccagggcggc ccagtcggga gcccggggac    360

cgagcttgtg ctgtggggaa acccccactt cttccaaggg acagcgatcc cgggacggtc    420

gaggcgtcgg ggcggtcacc gagacctctg cgggaagacc ccgtcgggga gagggcgcgc    480

agccccgaag cgtctcggga agtcgagcgg aatcgggcgg gatcacccgg gggcgcagag    540

cccccgtcgc gcctcgtgcg gcagcggaga gcccaggaga acgagccctc gggggccgaa    600

gcccatgccc gggttggggg cggctgccca gtgagtcctc ctggccggcc gggcggagaa    660

gagcgacacc gaagccggcg ggaggggagc acttcaaggc cggcggctgc ggaggatggg    720

cgcctgagcg gctccgagcg cagcgcggca gaggaaggcg aggcgagctt tggtgaggag    780

gcgccaaggg atcccgaagt gcagtctgcc cccgggaaga tggctcggcc tgggcagcgt    840

tggctcggca agtggcttgt ggcgatggtc gtgtgggcgc tgtgccggct cgccacaccg    900

ctggccaaga acctggagcc cgtatcctgg agctccctca accccaagtt cctgagtggg    960

aagggcttgg tgatctatcc gaaaattgga gacaagctgg acatcatctg cccccgagca   1020

gaagcagggc ggccctatga gtactacaag ctgtacctgg tgcggcctga gcaggcagct   1080

gcctgtagca cagttctcga ccccaacgtg ttggtcacct gcaataggcc agagcaggaa   1140

atacgcttta ccatcaagtt ccaggagttc agccccaact acatgggcct ggagttcaag   1200

aagcaccatg attactacat tacctcaaca tccaatggaa gcctggaggg gctggaaaac   1260

cgggagggcg gtgtgtgccg cacacgcacc atgaagatca tcatgaaggt tgggcaagat   1320

cccaatgctg tgacgcctga gcagctgact accagcaggc ccagcaagga ggcagacaac   1380

actgtcaaga tggccacaca ggcccctggt agtcggggct ccctgggtga ctctgatggc   1440

aagcatgaga ctgtgaacca ggaagagaag agtggcccag gtgcaagtgg gggcagcagc   1500

ggggaccctg atggcttctt caactccaag gtggcattgt tcgcggctgt cggtgccggt   1560

tgcgtcatct tcctgctcat catcatcttc ctgacggtcc tactactgaa gctacgcaag   1620

cggcaccgca agcacacaca gcagcgggcg gctgccctct cgctcagtac cctggccagt   1680

cccaaggggg gcagtggcac agcgggcacc gagcccagcg acatcatcat tcccttacgg   1740

actacagaga acaactactg cccccactat gagaaggtga gtggggacta cgggcaccct   1800

gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta caaggtctga   1860

gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac ctctcctttc   1920

gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt ttgtagtttc   1980

ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg gtgcttgtgc   2040

ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc tccgtggggg   2100

cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga gacagtcccc   2160

tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt ccgctatcat   2220

cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc atctgttttt   2280

tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga gcctggccca   2340

agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag gatgccattt   2400

cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc tgttcacgcc   2460

catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc ctgaccctcc   2520

tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac acacacacac   2580

acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc tgcctccctc   2640

actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag agctgctgca   2700

ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta tttgccctgc   2760

agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt ggcatccttt   2820

ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag accaggtggc   2880

ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca gctcctgctg   2940

ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg ctgggccagc   3000

ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac tgccacttga   3060

gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca caccatccac   3120

ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag ggagcagaac   3180

agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg ttgccatttg   3240

tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat aaactctgaa   3300

ttattttctt gttgcttttt tcttagaaaa aaatgagaac taaaaaaaaa aaattaacca   3360

catggagaaa tggg                                                     3374


<210>  10564
<211>  346
<212>  PRT
<213>  Homo sapiens

<400>  10564

Met Ala Arg Pro Gly Gln Arg Trp Leu Gly Lys Trp Leu Val Ala Met 
1               5                   10                  15


Val Val Trp Ala Leu Cys Arg Leu Ala Thr Pro Leu Ala Lys Asn Leu 
            20                  25                  30


Glu Pro Val Ser Trp Ser Ser Leu Asn Pro Lys Phe Leu Ser Gly Lys 
        35                  40                  45


Gly Leu Val Ile Tyr Pro Lys Ile Gly Asp Lys Leu Asp Ile Ile Cys 
    50                  55                  60


Pro Arg Ala Glu Ala Gly Arg Pro Tyr Glu Tyr Tyr Lys Leu Tyr Leu 
65                  70                  75                  80


Val Arg Pro Glu Gln Ala Ala Ala Cys Ser Thr Val Leu Asp Pro Asn 
                85                  90                  95


Val Leu Val Thr Cys Asn Arg Pro Glu Gln Glu Ile Arg Phe Thr Ile 
            100                 105                 110


Lys Phe Gln Glu Phe Ser Pro Asn Tyr Met Gly Leu Glu Phe Lys Lys 
        115                 120                 125


His His Asp Tyr Tyr Ile Thr Ser Thr Ser Asn Gly Ser Leu Glu Gly 
    130                 135                 140


Leu Glu Asn Arg Glu Gly Gly Val Cys Arg Thr Arg Thr Met Lys Ile 
145                 150                 155                 160


Ile Met Lys Val Gly Gln Asp Pro Asn Ala Val Thr Pro Glu Gln Leu 
                165                 170                 175


Thr Thr Ser Arg Pro Ser Lys Glu Ala Asp Asn Thr Val Lys Met Ala 
            180                 185                 190


Thr Gln Ala Pro Gly Ser Arg Gly Ser Leu Gly Asp Ser Asp Gly Lys 
        195                 200                 205


His Glu Thr Val Asn Gln Glu Glu Lys Ser Gly Pro Gly Ala Ser Gly 
    210                 215                 220


Gly Ser Ser Gly Asp Pro Asp Gly Phe Phe Asn Ser Lys Val Ala Leu 
225                 230                 235                 240


Phe Ala Ala Val Gly Ala Gly Cys Val Ile Phe Leu Leu Ile Ile Ile 
                245                 250                 255


Phe Leu Thr Val Leu Leu Leu Lys Leu Arg Lys Arg His Arg Lys His 
            260                 265                 270


Thr Gln Gln Arg Ala Ala Ala Leu Ser Leu Ser Thr Leu Ala Ser Pro 
        275                 280                 285


Lys Gly Gly Ser Gly Thr Ala Gly Thr Glu Pro Ser Asp Ile Ile Ile 
    290                 295                 300


Pro Leu Arg Thr Thr Glu Asn Asn Tyr Cys Pro His Tyr Glu Lys Val 
305                 310                 315                 320


Ser Gly Asp Tyr Gly His Pro Val Tyr Ile Val Gln Glu Met Pro Pro 
                325                 330                 335


Gln Ser Pro Ala Asn Ile Tyr Tyr Lys Val 
            340                 345


<210>  10565
<211>  1958
<212>  DNA
<213>  Homo sapiens

<400>  10565
gtctatgcga gctggacagc agtgggaggt ttgtgaggct cgcactggcc gcagaccctc     60

gggctcgatc gcccgggagc caggactcgg cgacgcgagg ctgccgggct acccggccga    120

ggcttcgggg gcgcaaacta atgggactgg ctcgctcggc agcatctccc cgctcttcta    180

agtacactga gcagggcccg cgctgaagta gaagctgtcc gggggcgcgt agcccggagt    240

cccagtgtgg cccggaggaa cggagcccgt gccagggcgg cccagtcggg agcccgggga    300

ccgagcttgt gctgtgggga aacccccact tcttccaagg gacagcgatc ccgggacggt    360

cgaggcgtcg gggcggtcac cgagacctct gcgggaagac cccgtcgggg agagggcgcg    420

cagccccgaa gcgtctcggg aagtcgagcg gaatcgggcg ggatcacccg ggggcgcaga    480

gcccccgtcg cgcctcgtgc ggcagcggag agcccccgag ggacagtcgg cctggaccgg    540

acctctcctt tcgcccccac accccctccc cttgccagct gtgcccacct ttgtatttag    600

ttttgtagtt tcttggcttt tataatcccc ctttttccct gccccctggg cttcggaggg    660

gggtgcttgt gcccctaacc cccatgctct tgtgccttcc ccctctggcc aggcctctgg    720

gctccgtggg ggcgcccctt cttggaaggc agggctggac actgatggac agcaggcagg    780

gagacagtcc cctggccctg cccctccctc gccccccttg ccaccttccc aggactgctt    840

gtccgctatc atcactgttt ttaatgcttt tgtgttcatt ttttagctgt caactcattt    900

tcatctgttt tttgaagaaa aatggaaaaa tgtaaaaggc agcccctccc caggctttgt    960

gagcctggcc caagccagta caagagggcc tggggcacga tgtggtcagc caggaagcat   1020

aggatgccat ttcttttata gattccttgg tatttctggt ggggtaaggg gcaggccagg   1080

gctgttcacg cccatgaggg aagaggaaag tgccactggg caaggtgtcc caccctcccc   1140

tcctgaccct cctacgaggc ttatcctggc aatggggtag tcactgccac ccttccacac   1200

acacacacac acacacacac acaaaaaaaa atcccttcct tgtgggattc ttgggcatct   1260

cctgcctccc tcactctcac ggtaattaat gtcttaattg gctgttgcct ggggaacagg   1320

agagctgctg caggcagatg acctcatggg gggtggaggg aggtgaggtg cccaggtggc   1380

tatttgccct gcagagctgg gagtttcacc cccacccccc accctgttct ctccttacct   1440

ttggcatcct ttggcctggt ggggaaacag aggcccaggg tggagaccta agcgggtata   1500

agaccaggtg gcctgctcct tttctgggcc ctagcacagg tgggtaaccc ccacccaacc   1560

cagctcctgc tgctgtccca gtcttgggct ggggcctgga aagaggaaga ggctgcctgg   1620

ggctgggcca gcccgctgtg cactttgacc ccagttcctt gccagcacgg ctgctaacag   1680

actgccactt gagtgcgcct tgcaggcact cccagagcag ccatggaagg agctggccct   1740

cacaccatcc acctccacac tgcctcctgg ccagctgccc accccagtgc caggtgggag   1800

agggagcaga acagccagcc ccttccaggt ggcagtcgga agggtttttg tttttgtttc   1860

tgttgccatt tgtgtaaata ctagtctttt tggaaaaaaa ataatgtaaa gatgttttgt   1920

ataaactctg aattattttc ttgttgcttt tttcttag                           1958


<210>  10566
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  10566

Met Leu Leu Cys Leu Pro Pro Leu Ala Arg Pro Leu Gly Ser Val Gly 
1               5                   10                  15


Ala Pro Leu Leu Gly Arg Gln Gly Trp Thr Leu Met Asp Ser Arg Gln 
            20                  25                  30


Gly Asp Ser Pro Leu Ala Leu Pro Leu Pro Arg Pro Pro Cys His Leu 
        35                  40                  45


Pro Arg Thr Ala Cys Pro Leu Ser Ser Leu Phe Leu Met Leu Leu Cys 
    50                  55                  60


Ser Phe Phe Ser Cys Gln Leu Ile Phe Ile Cys Phe Leu Lys Lys Asn 
65                  70                  75                  80


Gly Lys Met 



<210>  10567
<211>  2006
<212>  DNA
<213>  Homo sapiens

<400>  10567
gtctatgcga gctggacagc agtgggaggt ttgtgaggct cgcactggcc gcagaccctc     60

gggctcgatc gcccgggagc caggactcgg cgacgcgagg ctgccgggct acccggccga    120

ggcttcgggg gcgcaaacta atgggactgg ctcgctcggc agcatctccc cgctcttcta    180

agtacactga gcagggcccg cgctgaagta gaagctgtcc gggggcgcgt agcccggagt    240

cccagtgtgg cccggaggaa cggagcccgt gccagggcgg cccagtcggg agcccgggga    300

ccgagcttgt gctgtgggga aacccccact tcttccaagg gacagcgatc ccgggacggt    360

cgaggcgtcg gggcggtcac cgagacctct gcgggaagac cccgtcgggg agagggcgcg    420

cagccccgaa gcgtctcggg aagtcgagcg gaatcgggcg ggatcacccg ggggcgcaga    480

gcccccgtcg cgcctcgtgc ggcagcggag agcccccgag ggacagtcgg cctggaccgg    540

acctctcctt tcgcccccac accccctccc cttgccagct gtgcccacct ttgtatttag    600

ttttgtagtt tcttggcttt tataatcccc ctttttccct gccccctggg cttcggaggg    660

gggtgcttgt gcccctaacc cccatgctct tgtgccttcc ccctctggcc aggcctctgg    720

gctccgtggg ggcgcccctt cttggaaggc agggctggac actgatggac agcaggcagg    780

gagacagtcc cctggccctg cccctccctc gccccccttg ccaccttccc aggactgctt    840

gtccgctatc atcactgttt ttaatgcttt tgtgttcatt ttttagctgt caactcattt    900

tcatctgttt tttgaagaaa aatggaaaaa tgtaaaaggc agcccctccc caggctttgt    960

gagcctggcc caagccagta caagagggcc tggggcacga tgtggtcagc caggaagcat   1020

aggatgccat ttcttttata gattccttgg tatttctggt ggggtaaggg gcaggccagg   1080

gctgttcacg cccatgaggg aagaggaaag tgccactggg caaggtgtcc caccctcccc   1140

tcctgaccct cctacgaggc ttatcctggc aatggggtag tcactgccac ccttccacac   1200

acacacacac acacacacac acaaaaaaaa atcccttcct tgtgggattc ttgggcatct   1260

cctgcctccc tcactctcac ggtaattaat gtcttaattg gctgttgcct ggggaacagg   1320

agagctgctg caggcagatg acctcatggg gggtggaggg aggtgaggtg cccaggtggc   1380

tatttgccct gcagagctgg gagtttcacc cccacccccc accctgttct ctccttacct   1440

ttggcatcct ttggcctggt ggggaaacag aggcccaggg tggagaccta agcgggtata   1500

agaccaggtg gcctgctcct tttctgggcc ctagcacagg tgggtaaccc ccacccaacc   1560

cagctcctgc tgctgtccca gtcttgggct ggggcctgga aagaggaaga ggctgcctgg   1620

ggctgggcca gcccgctgtg cactttgacc ccagttcctt gccagcacgg ctgctaacag   1680

actgccactt gagtgcgcct tgcaggcact cccagagcag ccatggaagg agctggccct   1740

cacaccatcc acctccacac tgcctcctgg ccagctgccc accccagtgc caggtgggag   1800

agggagcaga acagccagcc ccttccaggt ggcagtcgga agggtttttg tttttgtttc   1860

tgttgccatt tgtgtaaata ctagtctttt tggaaaaaaa ataatgtaaa gatgttttgt   1920

ataaactctg aattattttc ttgttgcttt tttcttagaa aaaaatgaga actaaaaaaa   1980

aaaaattaac cacatggaga aatggg                                        2006


<210>  10568
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  10568

Met Leu Leu Cys Leu Pro Pro Leu Ala Arg Pro Leu Gly Ser Val Gly 
1               5                   10                  15


Ala Pro Leu Leu Gly Arg Gln Gly Trp Thr Leu Met Asp Ser Arg Gln 
            20                  25                  30


Gly Asp Ser Pro Leu Ala Leu Pro Leu Pro Arg Pro Pro Cys His Leu 
        35                  40                  45


Pro Arg Thr Ala Cys Pro Leu Ser Ser Leu Phe Leu Met Leu Leu Cys 
    50                  55                  60


Ser Phe Phe Ser Cys Gln Leu Ile Phe Ile Cys Phe Leu Lys Lys Asn 
65                  70                  75                  80


Gly Lys Met 



<210>  10569
<211>  1776
<212>  DNA
<213>  Homo sapiens

<400>  10569
atgcgagctg gacagcagtg ggaggtttgt gaggctcgca ctggccgcag accctcgggc     60

tcgatcgccc gggagccagg actcggcgac gcgaggctgc cgggctaccc ggccgaggct    120

tcgggggcgc aaactaatgg gactggctcg agcgggcacc gagcccagcg acatcatcat    180

tcccttacgg actacagaga acaactactg cccccactat gagaaggtga gtggggacta    240

cgggcaccct gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta    300

caaggtctga gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac    360

ctctcctttc gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt    420

ttgtagtttc ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg    480

gtgcttgtgc ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc    540

tccgtggggg cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga    600

gacagtcccc tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt    660

ccgctatcat cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc    720

atctgttttt tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga    780

gcctggccca agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag    840

gatgccattt cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc    900

tgttcacgcc catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc    960

ctgaccctcc tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac   1020

acacacacac acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc   1080

tgcctccctc actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag   1140

agctgctgca ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta   1200

tttgccctgc agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt   1260

ggcatccttt ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag   1320

accaggtggc ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca   1380

gctcctgctg ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg   1440

ctgggccagc ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac   1500

tgccacttga gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca   1560

caccatccac ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag   1620

ggagcagaac agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg   1680

ttgccatttg tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat   1740

aaactctgaa ttattttctt gttgcttttt tcttag                             1776


<210>  10570
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  10570

Met Arg Ala Gly Gln Gln Trp Glu Val Cys Glu Ala Arg Thr Gly Arg 
1               5                   10                  15


Arg Pro Ser Gly Ser Ile Ala Arg Glu Pro Gly Leu Gly Asp Ala Arg 
            20                  25                  30


Leu Pro Gly Tyr Pro Ala Glu Ala Ser Gly Ala Gln Thr Asn Gly Thr 
        35                  40                  45


Gly Ser Ser Gly His Arg Ala Gln Arg His His His Ser Leu Thr Asp 
    50                  55                  60


Tyr Arg Glu Gln Leu Leu Pro Pro Leu 
65                  70


<210>  10571
<211>  1656
<212>  DNA
<213>  Homo sapiens

<400>  10571
atgcgagctg gacagcagtg ggaggtttgt gaggctcgca ctggccgcag accctcgggc     60

tcgatcgccc gggagccagg actcggcgac gcgaggctgc cgggctaccc ggccgaggta    120

cgggcaccct gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta    180

caaggtctga gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac    240

ctctcctttc gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt    300

ttgtagtttc ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg    360

gtgcttgtgc ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc    420

tccgtggggg cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga    480

gacagtcccc tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt    540

ccgctatcat cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc    600

atctgttttt tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga    660

gcctggccca agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag    720

gatgccattt cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc    780

tgttcacgcc catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc    840

ctgaccctcc tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac    900

acacacacac acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc    960

tgcctccctc actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag   1020

agctgctgca ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta   1080

tttgccctgc agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt   1140

ggcatccttt ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag   1200

accaggtggc ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca   1260

gctcctgctg ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg   1320

ctgggccagc ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac   1380

tgccacttga gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca   1440

caccatccac ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag   1500

ggagcagaac agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg   1560

ttgccatttg tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat   1620

aaactctgaa ttattttctt gttgcttttt tcttag                             1656


<210>  10572
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  10572

Met Arg Ala Gly Gln Gln Trp Glu Val Cys Glu Ala Arg Thr Gly Arg 
1               5                   10                  15


Arg Pro Ser Gly Ser Ile Ala Arg Glu Pro Gly Leu Gly Asp Ala Arg 
            20                  25                  30


Leu Pro Gly Tyr Pro Ala Glu Val Arg Ala Pro Cys Leu His Arg Pro 
        35                  40                  45


Arg Asp Ala Ala Pro Glu Pro Gly Glu His Leu Leu Gln Gly Leu Ser 
    50                  55                  60


Ala Arg His Gly Leu Arg Pro Pro Arg Asp Ser Arg Pro Gly Pro Asp 
65                  70                  75                  80


Leu Ser Phe Arg Pro His Thr Pro Ser Pro Cys Gln Leu Cys Pro Pro 
                85                  90                  95


Leu Tyr Leu Val Leu 
            100


<210>  10573
<211>  1704
<212>  DNA
<213>  Homo sapiens

<400>  10573
atgcgagctg gacagcagtg ggaggtttgt gaggctcgca ctggccgcag accctcgggc     60

tcgatcgccc gggagccagg actcggcgac gcgaggctgc cgggctaccc ggccgaggta    120

cgggcaccct gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta    180

caaggtctga gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac    240

ctctcctttc gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt    300

ttgtagtttc ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg    360

gtgcttgtgc ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc    420

tccgtggggg cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga    480

gacagtcccc tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt    540

ccgctatcat cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc    600

atctgttttt tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga    660

gcctggccca agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag    720

gatgccattt cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc    780

tgttcacgcc catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc    840

ctgaccctcc tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac    900

acacacacac acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc    960

tgcctccctc actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag   1020

agctgctgca ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta   1080

tttgccctgc agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt   1140

ggcatccttt ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag   1200

accaggtggc ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca   1260

gctcctgctg ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg   1320

ctgggccagc ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac   1380

tgccacttga gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca   1440

caccatccac ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag   1500

ggagcagaac agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg   1560

ttgccatttg tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat   1620

aaactctgaa ttattttctt gttgcttttt tcttagaaaa aaatgagaac taaaaaaaaa   1680

aaattaacca catggagaaa tggg                                          1704


<210>  10574
<211>  101
<212>  PRT
<213>  Homo sapiens

<400>  10574

Met Arg Ala Gly Gln Gln Trp Glu Val Cys Glu Ala Arg Thr Gly Arg 
1               5                   10                  15


Arg Pro Ser Gly Ser Ile Ala Arg Glu Pro Gly Leu Gly Asp Ala Arg 
            20                  25                  30


Leu Pro Gly Tyr Pro Ala Glu Val Arg Ala Pro Cys Leu His Arg Pro 
        35                  40                  45


Arg Asp Ala Ala Pro Glu Pro Gly Glu His Leu Leu Gln Gly Leu Ser 
    50                  55                  60


Ala Arg His Gly Leu Arg Pro Pro Arg Asp Ser Arg Pro Gly Pro Asp 
65                  70                  75                  80


Leu Ser Phe Arg Pro His Thr Pro Ser Pro Cys Gln Leu Cys Pro Pro 
                85                  90                  95


Leu Tyr Leu Val Leu 
            100


<210>  10575
<211>  1824
<212>  DNA
<213>  Homo sapiens

<400>  10575
atgcgagctg gacagcagtg ggaggtttgt gaggctcgca ctggccgcag accctcgggc     60

tcgatcgccc gggagccagg actcggcgac gcgaggctgc cgggctaccc ggccgaggct    120

tcgggggcgc aaactaatgg gactggctcg agcgggcacc gagcccagcg acatcatcat    180

tcccttacgg actacagaga acaactactg cccccactat gagaaggtga gtggggacta    240

cgggcaccct gtctacatcg tccaagagat gccgccccag agcccggcga acatctacta    300

caaggtctga gtgcccggca cggcctcagg cccccgaggg acagtcggcc tggaccggac    360

ctctcctttc gcccccacac cccctcccct tgccagctgt gcccaccttt gtatttagtt    420

ttgtagtttc ttggctttta taatccccct ttttccctgc cccctgggct tcggaggggg    480

gtgcttgtgc ccctaacccc catgctcttg tgccttcccc ctctggccag gcctctgggc    540

tccgtggggg cgccccttct tggaaggcag ggctggacac tgatggacag caggcaggga    600

gacagtcccc tggccctgcc cctccctcgc cccccttgcc accttcccag gactgcttgt    660

ccgctatcat cactgttttt aatgcttttg tgttcatttt ttagctgtca actcattttc    720

atctgttttt tgaagaaaaa tggaaaaatg taaaaggcag cccctcccca ggctttgtga    780

gcctggccca agccagtaca agagggcctg gggcacgatg tggtcagcca ggaagcatag    840

gatgccattt cttttataga ttccttggta tttctggtgg ggtaaggggc aggccagggc    900

tgttcacgcc catgagggaa gaggaaagtg ccactgggca aggtgtccca ccctcccctc    960

ctgaccctcc tacgaggctt atcctggcaa tggggtagtc actgccaccc ttccacacac   1020

acacacacac acacacacac aaaaaaaaat cccttccttg tgggattctt gggcatctcc   1080

tgcctccctc actctcacgg taattaatgt cttaattggc tgttgcctgg ggaacaggag   1140

agctgctgca ggcagatgac ctcatggggg gtggagggag gtgaggtgcc caggtggcta   1200

tttgccctgc agagctggga gtttcacccc caccccccac cctgttctct ccttaccttt   1260

ggcatccttt ggcctggtgg ggaaacagag gcccagggtg gagacctaag cgggtataag   1320

accaggtggc ctgctccttt tctgggccct agcacaggtg ggtaaccccc acccaaccca   1380

gctcctgctg ctgtcccagt cttgggctgg ggcctggaaa gaggaagagg ctgcctgggg   1440

ctgggccagc ccgctgtgca ctttgacccc agttccttgc cagcacggct gctaacagac   1500

tgccacttga gtgcgccttg caggcactcc cagagcagcc atggaaggag ctggccctca   1560

caccatccac ctccacactg cctcctggcc agctgcccac cccagtgcca ggtgggagag   1620

ggagcagaac agccagcccc ttccaggtgg cagtcggaag ggtttttgtt tttgtttctg   1680

ttgccatttg tgtaaatact agtctttttg gaaaaaaaat aatgtaaaga tgttttgtat   1740

aaactctgaa ttattttctt gttgcttttt tcttagaaaa aaatgagaac taaaaaaaaa   1800

aaattaacca catggagaaa tggg                                          1824


<210>  10576
<211>  73
<212>  PRT
<213>  Homo sapiens

<400>  10576

Met Arg Ala Gly Gln Gln Trp Glu Val Cys Glu Ala Arg Thr Gly Arg 
1               5                   10                  15


Arg Pro Ser Gly Ser Ile Ala Arg Glu Pro Gly Leu Gly Asp Ala Arg 
            20                  25                  30


Leu Pro Gly Tyr Pro Ala Glu Ala Ser Gly Ala Gln Thr Asn Gly Thr 
        35                  40                  45


Gly Ser Ser Gly His Arg Ala Gln Arg His His His Ser Leu Thr Asp 
    50                  55                  60


Tyr Arg Glu Gln Leu Leu Pro Pro Leu 
65                  70


<210>  10577
<211>  1443
<212>  DNA
<213>  Homo sapiens

<400>  10577
cggggaccct gatggcttct tcaactccaa ggtggcattg ttcgcggctg tcggtgccgg     60

ttgcgtcatc ttcctgctca tcatcatctt cctgacggtc ctactactga agctacgcaa    120

gcggcaccgc aagcacacac agcagcgggc ggctgccctc tcgctcagta ccctggccag    180

tcccaagggg ggcagtggca cagcgggcac cgagcccagc gacatcatca ttcccttacg    240

gactacagag aacaactact gcccccacta tgagaaggtg agtggggact acgggcaccc    300

tgtctacatc gtccaagaga tgccgcccca gagcccggcg aacatctact acaaggtctg    360

agtgcccggc acggcctcag gcccccgagg gacagtcggc ctggaccgga cctctccttt    420

cgcccccaca ccccctcccc ttgccagctg tgcccacctt tgtatttagt tttgtagttt    480

cttggctttt ataatccccc tttttccctg ccccctgggc ttcggagggg ggtgcttgtg    540

cccctaaccc ccatgctctt gtgccttccc cctctggcca ggcctctggg ctccgtgggg    600

gcgccccttc ttggaaggca gggctggaca ctgatggaca gcaggcaggg agacagtccc    660

ctggccctgc ccctccctcg ccccccttgc caccttccca ggactgcttg tccgctatca    720

tcactgtttt taatgctttt gtgttcattt tttagctgtc aactcatttt catctgtttt    780

ttgaagaaaa atggaaaaat gtaaaaggca gcccctcccc aggctttgtg agcctggccc    840

aagccagtac aagagggcct ggggcacgat gtggtcagcc aggaagcata ggatgccatt    900

tcttttatag attccttggt atttctggtg gggtaagggg caggccaggg ctgttcacgc    960

ccatgaggga agaggaaagt gccactgggc aaggtgtccc accctcccct cctgaccctc   1020

ctacgaggct tatcctggca atggggtagt cactgccacc cttccacaca cacacacaca   1080

cacacacaca caaaaaaaaa tcccttcctt gtgggattct tgggcatctc ctgcctccct   1140

cactctcacg cacggctgct aacagactgc cacttgagtg cgccttgcag gcactcccag   1200

agcagccatg gaaggagctg gccctcacac catccacctc cacactgcct cctggccagc   1260

tgcccacccc agtgccaggt gggagaggga gcagaacagc cagccccttc caggtggcag   1320

tcggaagggt ttttgttttt gtttctgttg ccatttgtgt aaatactagt ctttttggaa   1380

aaaaaataat gtaaagatgt tttgtataaa ctctgaatta ttttcttgtt gcttttttct   1440

tag                                                                 1443


<210>  10578
<211>  83
<212>  PRT
<213>  Homo sapiens

<400>  10578

Met Leu Leu Cys Leu Pro Pro Leu Ala Arg Pro Leu Gly Ser Val Gly 
1               5                   10                  15


Ala Pro Leu Leu Gly Arg Gln Gly Trp Thr Leu Met Asp Ser Arg Gln 
            20                  25                  30


Gly Asp Ser Pro Leu Ala Leu Pro Leu Pro Arg Pro Pro Cys His Leu 
        35                  40                  45


Pro Arg Thr Ala Cys Pro Leu Ser Ser Leu Phe Leu Met Leu Leu Cys 
    50                  55                  60


Ser Phe Phe Ser Cys Gln Leu Ile Phe Ile Cys Phe Leu Lys Lys Asn 
65                  70                  75                  80


Gly Lys Met 



<210>  10579
<211>  687
<212>  DNA
<213>  Homo sapiens

<400>  10579
ttgttcgcgg ctgtcggtgc cggttgcgtc atcttcctgc tcatcatcat cttcctgacg     60

gtcctactac tgaagctacg caagcggcac cgcaagcaca cacagcagcg ggcggctgcc    120

ctctcgctca gtaccctggc cagtcccaag gggggcagtg gcacagcggg caccgagccc    180

agcgacatca tcattcctcc ttttctgggc cctagcacag gtgggtaacc cccacccaac    240

ccagctcctg ctgctgtccc agtcttgggc tggggcctgg aaagaggaag aggctgcctg    300

gggctgggcc agcccgctgt gcactttgac cccagttcct tgccagcacg gctgctaaca    360

gactgccact tgagtgcgcc ttgcaggcac tcccagagca gccatggaag gagctggccc    420

tcacaccatc cacctccaca ctgcctcctg gccagctgcc caccccagtg ccaggtggga    480

gagggagcag aacagccagc cccttccagg tggcagtcgg aagggttttt gtttttgttt    540

ctgttgccat ttgtgtaaat actagtcttt ttggaaaaaa aataatgtaa agatgttttg    600

tataaactct gaattatttt cttgttgctt ttttcttaga aaaaaatgag aactaaaaaa    660

aaaaaattaa ccacatggag aaatggg                                        687


<210>  10580
<211>  53
<212>  PRT
<213>  Homo sapiens

<400>  10580

Met Glu Gly Ala Gly Pro His Thr Ile His Leu His Thr Ala Ser Trp 
1               5                   10                  15


Pro Ala Ala His Pro Ser Ala Arg Trp Glu Arg Glu Gln Asn Ser Gln 
            20                  25                  30


Pro Leu Pro Gly Gly Ser Arg Lys Gly Phe Cys Phe Cys Phe Cys Cys 
        35                  40                  45


His Leu Cys Lys Tyr 
    50


<210>  10581
<211>  1069
<212>  DNA
<213>  Homo sapiens

<400>  10581
gcagcgggcg gctgccctct cgctcagtac cctggccagt cccaaggggg gcagtggcac     60

agcgggcacc gagcccagcg acatcatcat tcccttacgg actacagaga acaactactg    120

cccccactat gagaaggtga gtggggacta cgggcaccct gtctacatcg tccaagagat    180

gccgccccag agcccggcga acatctacta caaggtctga gtgcccggca cggcctcagg    240

cccccgaggg acagtcggcc tggaccggac ctctcctttc gcccccacac cccctcccct    300

tgccagctgt gcccaccttt gtatttagtt ttgtagtttc ttggctttta taatccccct    360

ttttccctgc cccctgggct tcggaggggg gtgcttgtgc ccctaacccc catgctcttg    420

tgccttcccc ctctggccag gcctctgggc tccgtggggg cgccccttct tggaaggcag    480

ggctggacac tgatggacag caggcaggga gacagtcccc tggccctgcc cctccctcgc    540

cccccttgcc accttcccag gactgcttgt ccgctatcat cactgttttt aatgcttttg    600

tgttcatttt ttagctgtca actcattttc atctgttttt tgaagaaaaa tggaaaaatg    660

taaaaggcag cccctcccca ggctttgtga gcctggccca agccagtaca agagggcctg    720

gggcacgatg tggtcagcca ggaagcatag gatgccattt cttttataga ttccttggta    780

tttctggtgg ggtaaggggc aggccagggc tgttcacgcc catgagggaa gaggaaagtg    840

ccactgggca aggtgtccca cccatccacc tccacactgc ctcctggcca gctgcccacc    900

ccagtgccag gtgggagagg gagcagaaca gccagcccct tccaggtggc agtcggaagg    960

gtttttgttt ttgtttctgt tgccatttgt gtaaatacta gtctttttgg aaaaaaaata   1020

atgtaaagat gttttgtata aactctgaat tattttcttg ttgcttttt               1069


<210>  10582
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  10582

Met Arg Glu Glu Glu Ser Ala Thr Gly Gln Gly Val Pro Pro Ile His 
1               5                   10                  15


Leu His Thr Ala Ser Trp Pro Ala Ala His Pro Ser Ala Arg Trp Glu 
            20                  25                  30


Arg Glu Gln Asn Ser Gln Pro Leu Pro Gly Gly Ser Arg Lys Gly Phe 
        35                  40                  45


Cys Phe Cys Phe Cys Cys His Leu Cys Lys Tyr 
    50                  55


<210>  10583
<211>  1192
<212>  DNA
<213>  Homo sapiens

<400>  10583
ctctgggctc cgtgggggcg ccccttcttg gaaggcaggg ctggacactg atggacagca     60

ggcagggaga cagtcccctg gccctgcccc tccctcgccc cccttgccac cttcccagga    120

ctgcttgtcc gctatcatca ctgtttttaa tgcttttgtg ttcatttttt agctgtcaac    180

tcattttcat ctgttttttg aagaaaaatg gaaaaatgta aaaggcagcc cctccccagg    240

ctttgtgagc ctggcccaag ccagtacaag agggcctggg gcacgatgtg gtcagccagg    300

aagcatagga tgccatttct tttatagatt ccttggtatt tctggtgggg taaggggcag    360

gccagggctg ttcacgccca tgagggaaga ggaaagtgcc actgggcaag gtgtcccacc    420

ctcccctcct gaccctccta cgaggcttat cctggcaatg gggtagtcac tgccaccctt    480

ccacacacac acacacacac acacacacaa aaaaaaatcc cttccttgtg ggattcttgg    540

gcatctcctg cctccctcac tctcacggta attaatgtct taattggctg ttgcctgggg    600

aacaggagag ctgctgcagg cagatgacct catggggggt ggagggaggt gaggtgccca    660

ggtggctatt tgccctgcag agctgggagt ttcaccccca ccccccaccc tgttctctcc    720

ttacctttgg catcctttgg cctggtgggg aaacagaggc ccagggtgga gacctaagcg    780

ggtataagac caggtggcct gctccttttc tgggccctag cacaggtggg taacccccac    840

ccaacccagc tcctgctgct gtcccagtct tgggctgggg cctggaaaga ggaagaggct    900

gcctggggct gggccagccc gctgtgcact ttgaccccag ttccttgcca gcacggctgc    960

taacagactg ccacttgagt gcgccttgca ggcactccca gaaacagcca gccccttcca   1020

ggtggcagtc ggaagggttt ttgtttttgt ttctgttgcc atttgtgtaa atactagtct   1080

ttttggaaaa aaaataatgt aaagatgttt tgtataaact ctgaattatt ttcttgttgc   1140

ttttttctta gaaaaaaatg agaactaaaa aaaaaaaatt aaccacatgg ag           1192


<210>  10584
<211>  69
<212>  PRT
<213>  Homo sapiens

<400>  10584

Met Thr Ser Trp Gly Val Glu Gly Gly Glu Val Pro Arg Trp Leu Phe 
1               5                   10                  15


Ala Leu Gln Ser Trp Glu Phe His Pro His Pro Pro Pro Cys Ser Leu 
            20                  25                  30


Leu Thr Phe Gly Ile Leu Trp Pro Gly Gly Glu Thr Glu Ala Gln Gly 
        35                  40                  45


Gly Asp Leu Ser Gly Tyr Lys Thr Arg Trp Pro Ala Pro Phe Leu Gly 
    50                  55                  60


Pro Ser Thr Gly Gly 
65


<210>  10585
<211>  2201
<212>  DNA
<213>  Homo sapiens

<400>  10585
gaaaaatgtt agaaaccagg aagacaactc tacttttttg cattggggga ataaacaaac     60

caactaacca actaaaataa tacacttact ccaactaaga caacatagga agaccagaga    120

gatgattgga gtcaccaagt tgaagtacat tagtttggga tgataattcc ttatgacagt    180

gtttatccaa atctgtcatg gaaatactac atcttgacat gcccttagac ttctgtctga    240

acattgctaa actgctgatg gatcatgaaa gagaatctgt tgggtttcat ttcctgacga    300

ttattcatga acgttttaag tcatcggaaa atattggaaa agttctgata ctccatactg    360

acatgctttt acaaaggaag gaagaacttc ttgccaagga gaagattgaa gaaatctttt    420

tagctcacca aacaggaaga caactgacag cagaatcaat gaactggtta cacaacattc    480

tgtggagaca agctgccagt agttttgagg tacaaaatta cactgatgcc ctacaatggt    540

actattattc tctgaggttt tattcaactg atgaaatgga tctggacttc accaagctgc    600

agaggaacat ggcttgctgt tacctgaatt tgcaacaact tgataaggcc aaagaggcag    660

tggcagaagc tgaacgacat gaccctagga acgttttcac tcaattttat atattcaaga    720

ttgcagtcat agagggcaac tctgaaagag ctttgcaggc aataattact ttagagaata    780

tattaacaga tgaagagtca gaagataatg atctagttgc agagagaggt tcacctacca    840

tgcttctaag tttagctgcc cagtttgctc tagagaatgg acaacaaatt gtggcagaaa    900

aagctttgga atatttagct caacattcag aagaccagga acaagttctt acagctgtaa    960

agtgtttgct tcgttttctt cttccaaaaa ttgctgaaat gccggaatct gaagataaga   1020

agaaagaaat ggatcgactt ttgacttgcc tgaatagagc ctttgtgaaa ctttctcagc   1080

cttttggtga agaagcctta agtttggagt caagagctaa tgaagctcag tggtttcgaa   1140

aaacagcttg gaacttggct gtgcaatgtg acaaagatcc agtgatgatg agagagtttt   1200

ttatactttc ttataagatg tcccagtttt gtccttctga tcaagtaatt ctgattgcac   1260

ggaaaacatg tttacttatg gcagttgcag ttgatctaga gcaagggaga aaagcttcaa   1320

cagcttttga acagaccatg ttcctgagtc gtgcacttga ggagatccag acatgcaatg   1380

acatccataa tttcctgaaa caaacaggga ccttctcaaa tgattcatgt gagaaattgc   1440

ttctgctgta cgagtttgaa gttagagcca aattgaatga tccattactg gaaagcttcc   1500

tggaatcagt gtgggagttg cctcatttag aaactaaaac ttttgaaaca attgcaataa   1560

tagcaatgga aaagcctgca cactatcctt tgattgctct caaggccttg aaaaaggctt   1620

tattgctcta caaaaaggaa gaaccaattg atatatcaca atacagcaaa tgtatgcaca   1680

acttggttaa cctctcagtg ccagatgggg cgtcgaatgt agagctctgt cccctggaag   1740

aagtttgggg ctattttgaa gatgctctga gccacattag ccgcactaaa gactacccag   1800

aaatggagat tctctggctg atggtcaagt cctggaatac cggagtactt atgtttagca   1860

ggagcaagta tgcatctgct gaaaagtggt gtggcctggc cttgcgtttc cttaaccacc   1920

ttacctcctt caaggaaagc tatgaaactc agatgaatat gctgtatagt cagcttgtgg   1980

aagcattgag taacaacaag ggcccagttt ttcatgaaca tggctactgg agcaagtcag   2040

attaggcaag ctcatggcca catgaagaag atacattgtc ccgagatgct gactgtttaa   2100

atttttgcca gagtttctct tgagcttttg tttctgtttg ctcagaccct gttttcatgt   2160

tgttgaataa actttctaaa ataaaagcat gctgaattta c                       2201


<210>  10586
<211>  615
<212>  PRT
<213>  Homo sapiens

<400>  10586

Met Glu Ile Leu His Leu Asp Met Pro Leu Asp Phe Cys Leu Asn Ile 
1               5                   10                  15


Ala Lys Leu Leu Met Asp His Glu Arg Glu Ser Val Gly Phe His Phe 
            20                  25                  30


Leu Thr Ile Ile His Glu Arg Phe Lys Ser Ser Glu Asn Ile Gly Lys 
        35                  40                  45


Val Leu Ile Leu His Thr Asp Met Leu Leu Gln Arg Lys Glu Glu Leu 
    50                  55                  60


Leu Ala Lys Glu Lys Ile Glu Glu Ile Phe Leu Ala His Gln Thr Gly 
65                  70                  75                  80


Arg Gln Leu Thr Ala Glu Ser Met Asn Trp Leu His Asn Ile Leu Trp 
                85                  90                  95


Arg Gln Ala Ala Ser Ser Phe Glu Val Gln Asn Tyr Thr Asp Ala Leu 
            100                 105                 110


Gln Trp Tyr Tyr Tyr Ser Leu Arg Phe Tyr Ser Thr Asp Glu Met Asp 
        115                 120                 125


Leu Asp Phe Thr Lys Leu Gln Arg Asn Met Ala Cys Cys Tyr Leu Asn 
    130                 135                 140


Leu Gln Gln Leu Asp Lys Ala Lys Glu Ala Val Ala Glu Ala Glu Arg 
145                 150                 155                 160


His Asp Pro Arg Asn Val Phe Thr Gln Phe Tyr Ile Phe Lys Ile Ala 
                165                 170                 175


Val Ile Glu Gly Asn Ser Glu Arg Ala Leu Gln Ala Ile Ile Thr Leu 
            180                 185                 190


Glu Asn Ile Leu Thr Asp Glu Glu Ser Glu Asp Asn Asp Leu Val Ala 
        195                 200                 205


Glu Arg Gly Ser Pro Thr Met Leu Leu Ser Leu Ala Ala Gln Phe Ala 
    210                 215                 220


Leu Glu Asn Gly Gln Gln Ile Val Ala Glu Lys Ala Leu Glu Tyr Leu 
225                 230                 235                 240


Ala Gln His Ser Glu Asp Gln Glu Gln Val Leu Thr Ala Val Lys Cys 
                245                 250                 255


Leu Leu Arg Phe Leu Leu Pro Lys Ile Ala Glu Met Pro Glu Ser Glu 
            260                 265                 270


Asp Lys Lys Lys Glu Met Asp Arg Leu Leu Thr Cys Leu Asn Arg Ala 
        275                 280                 285


Phe Val Lys Leu Ser Gln Pro Phe Gly Glu Glu Ala Leu Ser Leu Glu 
    290                 295                 300


Ser Arg Ala Asn Glu Ala Gln Trp Phe Arg Lys Thr Ala Trp Asn Leu 
305                 310                 315                 320


Ala Val Gln Cys Asp Lys Asp Pro Val Met Met Arg Glu Phe Phe Ile 
                325                 330                 335


Leu Ser Tyr Lys Met Ser Gln Phe Cys Pro Ser Asp Gln Val Ile Leu 
            340                 345                 350


Ile Ala Arg Lys Thr Cys Leu Leu Met Ala Val Ala Val Asp Leu Glu 
        355                 360                 365


Gln Gly Arg Lys Ala Ser Thr Ala Phe Glu Gln Thr Met Phe Leu Ser 
    370                 375                 380


Arg Ala Leu Glu Glu Ile Gln Thr Cys Asn Asp Ile His Asn Phe Leu 
385                 390                 395                 400


Lys Gln Thr Gly Thr Phe Ser Asn Asp Ser Cys Glu Lys Leu Leu Leu 
                405                 410                 415


Leu Tyr Glu Phe Glu Val Arg Ala Lys Leu Asn Asp Pro Leu Leu Glu 
            420                 425                 430


Ser Phe Leu Glu Ser Val Trp Glu Leu Pro His Leu Glu Thr Lys Thr 
        435                 440                 445


Phe Glu Thr Ile Ala Ile Ile Ala Met Glu Lys Pro Ala His Tyr Pro 
    450                 455                 460


Leu Ile Ala Leu Lys Ala Leu Lys Lys Ala Leu Leu Leu Tyr Lys Lys 
465                 470                 475                 480


Glu Glu Pro Ile Asp Ile Ser Gln Tyr Ser Lys Cys Met His Asn Leu 
                485                 490                 495


Val Asn Leu Ser Val Pro Asp Gly Ala Ser Asn Val Glu Leu Cys Pro 
            500                 505                 510


Leu Glu Glu Val Trp Gly Tyr Phe Glu Asp Ala Leu Ser His Ile Ser 
        515                 520                 525


Arg Thr Lys Asp Tyr Pro Glu Met Glu Ile Leu Trp Leu Met Val Lys 
    530                 535                 540


Ser Trp Asn Thr Gly Val Leu Met Phe Ser Arg Ser Lys Tyr Ala Ser 
545                 550                 555                 560


Ala Glu Lys Trp Cys Gly Leu Ala Leu Arg Phe Leu Asn His Leu Thr 
                565                 570                 575


Ser Phe Lys Glu Ser Tyr Glu Thr Gln Met Asn Met Leu Tyr Ser Gln 
            580                 585                 590


Leu Val Glu Ala Leu Ser Asn Asn Lys Gly Pro Val Phe His Glu His 
        595                 600                 605


Gly Tyr Trp Ser Lys Ser Asp 
    610                 615


<210>  10587
<211>  3141
<212>  DNA
<213>  Homo sapiens

<400>  10587
gtcctcgtgc gctgtggacg gaggttgtgg agagagcagg gcggcattgg tggctgcggc     60

tgaggcttga gccagagatt taaaaatgga caatgatgat tttttttcca tggactttaa    120

agatggagtc tgtctctgtt gtccaggctg gagtgcagtg gcatgatctc ggctcactgc    180

aacctccgcc tcctgtgttc aagcgattct tctgcctcag cctcccaagt agctgggact    240

acagaagttg ttgaaaacct ggttacaaat gataattcac ctaacatacc agaggcaatt    300

gatagactct tcagcgacat agcaaatatc aacagggagt ctatggctga aataacagac    360

attcagattg aagaaatggc agtaaaccta tggaactggg cacttaccat aggaggaggt    420

tggcttgtaa atgaagagca gaaaattaga ttacattatg ttgcttgcaa gttgctgagt    480

atgtgtgaag cctcatttgc ctcagaacaa agtattcaac gactgattat gatgaatatg    540

agaataggaa aagaatggtt ggatgctgga aattttctaa tcgctgatga atgttttcaa    600

gctgctgtgg ccagtctgga gcaattatac gtcaaattaa ttcaaaggag ctcccctgag    660

gctgacttga ccatggagaa gattactgtt gagagtgacc acttcagagt gctttcttac    720

caagcagagt cagcagttgc tcaaggggat tttcaaagag catctatgtg tgtactgcaa    780

tgtaaagata tgttgatgag gctcccccag atgacttcaa gtcttcatca tctctgttac    840

aactttggag tagaaaccca gaagaataat aaatatgaag aaagttcttt ctggcttagc    900

caaagctatg atattgggaa gatggataag aaatctactg ggccagaaat gctggctaaa    960

gttctacggc tattagccac gaattatttg gattgggatg acaccaaata ttatgataag   1020

gctctcaatg ctgtaaacct agcaaacaag gaacatttaa gttctcctgg gcttttctta   1080

aaaatgaaaa tcctcttgaa aggcgaaaca tctaatgaag aactccttga agctgtcatg   1140

gaaatactac atcttgacat gcccttagac ttctgtctga acattgctaa actgctgatg   1200

gatcatgaaa gagaatctgt tgggtttcat ttcctgacga ttattcatga acgttttaag   1260

tcatcggaaa atattggaaa agttctgata ctccatactg acatgctttt acaaaggaag   1320

gaagaacttc ttgccaagga gaagattgaa gaaatctttt tagctcacca aacaggaaga   1380

caactgacag cagaatcaat gaactggtta cacaacattc tgtggagaca agctgccagt   1440

agttttgagg tacaaaatta cactgatgcc ctacaatggt actattattc tctgaggttt   1500

tattcaactg atgaaatgga tctggacttc accaagctgc agaggaacat ggcttgctgt   1560

tacctgaatt tgcaacaact tgataaggcc aaagaggcag tggcagaagc tgaacgacat   1620

gaccctagga acgttttcac tcaattttat atattcaaga ttgcagtcat agagggcaac   1680

tctgaaagag ctttgcaggc aataattact ttagagaata tattaacaga tgaagagtca   1740

gaagataatg atctagttgc agagagaggt tcacctacca tgcttctaag tttagctgcc   1800

cagtttgctc tagagaatgg acaacaaatt gtggcagaaa aagctttgga atatttagct   1860

caacattcag aagaccagga acaagttctt acagctgtaa agtgtttgct tcgttttctt   1920

cttccaaaaa ttgctgaaat gccggaatct gaagataaga agaaagaaat ggatcgactt   1980

ttgacttgcc tgaatagagc ctttgtgaaa ctttctcagc cttttggtga agaagcctta   2040

agtttggagt caagagctaa tgaagctcag tggtttcgaa aaacagcttg gaacttggct   2100

gtgcaatgtg acaaagatcc agtgatgatg agagagtttt ttatactttc ttataagatg   2160

tcccagtttt gtccttctga tcaagtaatt ctgattgcac ggaaaacatg tttacttatg   2220

gcagttgcag ttgatctaga gcaagggaga aaagcttcaa cagcttttga acagaccatg   2280

ttcctgagtc gtgcacttga ggagatccag acatgcaatg acatccataa tttcctgaaa   2340

caaacaggga ccttctcaaa tgattcatgt gagaaattgc ttctgctgta cgagtttgaa   2400

gttagagcca aattgaatga tccattactg gaaagcttcc tggaatcagt gtgggagttg   2460

cctcatttag aaactaaaac ttttgaaaca attgcaataa tagcaatgga aaagcctgca   2520

cactatcctt tgattgctct caaggccttg aaaaaggctt tattgctcta caaaaaggaa   2580

gaaccaattg atatatcaca atacagcaaa tgtatgcaca acttggttaa cctctcagtg   2640

ccagatgggg cgtcgaatgt agagctctgt cccctggaag aagtttgggg ctattttgaa   2700

gatgctctga gccacattag ccgcactaaa gactacccag aaatggagat tctctggctg   2760

atggtcaagt cctggaatac cggagtactt atgtttagca ggagcaagta tgcatctgct   2820

gaaaagtggt gtggcctggc cttgcgtttc cttaaccacc ttacctcctt caaggaaagc   2880

tatgaaactc agatgaatat gctgtatagt cagcttgtgg aagcattgag taacaacaag   2940

ggcccagttt ttcatgaaca tggctactgg agcaagtcag attaggcaag ctcatggcca   3000

catgaagaag atacattgtc ccgagatgct gactgtttaa atttttgcca gagtttctct   3060

tgagcttttg tttctgtttg ctcagaccct gttttcatgt tgttgaataa actttctaaa   3120

ataaaagcat gctgaattta c                                             3141


<210>  10588
<211>  940
<212>  PRT
<213>  Homo sapiens

<400>  10588

Met Ile Ser Ala His Cys Asn Leu Arg Leu Leu Cys Ser Ser Asp Ser 
1               5                   10                  15


Ser Ala Ser Ala Ser Gln Val Ala Gly Thr Thr Glu Val Val Glu Asn 
            20                  25                  30


Leu Val Thr Asn Asp Asn Ser Pro Asn Ile Pro Glu Ala Ile Asp Arg 
        35                  40                  45


Leu Phe Ser Asp Ile Ala Asn Ile Asn Arg Glu Ser Met Ala Glu Ile 
    50                  55                  60


Thr Asp Ile Gln Ile Glu Glu Met Ala Val Asn Leu Trp Asn Trp Ala 
65                  70                  75                  80


Leu Thr Ile Gly Gly Gly Trp Leu Val Asn Glu Glu Gln Lys Ile Arg 
                85                  90                  95


Leu His Tyr Val Ala Cys Lys Leu Leu Ser Met Cys Glu Ala Ser Phe 
            100                 105                 110


Ala Ser Glu Gln Ser Ile Gln Arg Leu Ile Met Met Asn Met Arg Ile 
        115                 120                 125


Gly Lys Glu Trp Leu Asp Ala Gly Asn Phe Leu Ile Ala Asp Glu Cys 
    130                 135                 140


Phe Gln Ala Ala Val Ala Ser Leu Glu Gln Leu Tyr Val Lys Leu Ile 
145                 150                 155                 160


Gln Arg Ser Ser Pro Glu Ala Asp Leu Thr Met Glu Lys Ile Thr Val 
                165                 170                 175


Glu Ser Asp His Phe Arg Val Leu Ser Tyr Gln Ala Glu Ser Ala Val 
            180                 185                 190


Ala Gln Gly Asp Phe Gln Arg Ala Ser Met Cys Val Leu Gln Cys Lys 
        195                 200                 205


Asp Met Leu Met Arg Leu Pro Gln Met Thr Ser Ser Leu His His Leu 
    210                 215                 220


Cys Tyr Asn Phe Gly Val Glu Thr Gln Lys Asn Asn Lys Tyr Glu Glu 
225                 230                 235                 240


Ser Ser Phe Trp Leu Ser Gln Ser Tyr Asp Ile Gly Lys Met Asp Lys 
                245                 250                 255


Lys Ser Thr Gly Pro Glu Met Leu Ala Lys Val Leu Arg Leu Leu Ala 
            260                 265                 270


Thr Asn Tyr Leu Asp Trp Asp Asp Thr Lys Tyr Tyr Asp Lys Ala Leu 
        275                 280                 285


Asn Ala Val Asn Leu Ala Asn Lys Glu His Leu Ser Ser Pro Gly Leu 
    290                 295                 300


Phe Leu Lys Met Lys Ile Leu Leu Lys Gly Glu Thr Ser Asn Glu Glu 
305                 310                 315                 320


Leu Leu Glu Ala Val Met Glu Ile Leu His Leu Asp Met Pro Leu Asp 
                325                 330                 335


Phe Cys Leu Asn Ile Ala Lys Leu Leu Met Asp His Glu Arg Glu Ser 
            340                 345                 350


Val Gly Phe His Phe Leu Thr Ile Ile His Glu Arg Phe Lys Ser Ser 
        355                 360                 365


Glu Asn Ile Gly Lys Val Leu Ile Leu His Thr Asp Met Leu Leu Gln 
    370                 375                 380


Arg Lys Glu Glu Leu Leu Ala Lys Glu Lys Ile Glu Glu Ile Phe Leu 
385                 390                 395                 400


Ala His Gln Thr Gly Arg Gln Leu Thr Ala Glu Ser Met Asn Trp Leu 
                405                 410                 415


His Asn Ile Leu Trp Arg Gln Ala Ala Ser Ser Phe Glu Val Gln Asn 
            420                 425                 430


Tyr Thr Asp Ala Leu Gln Trp Tyr Tyr Tyr Ser Leu Arg Phe Tyr Ser 
        435                 440                 445


Thr Asp Glu Met Asp Leu Asp Phe Thr Lys Leu Gln Arg Asn Met Ala 
    450                 455                 460


Cys Cys Tyr Leu Asn Leu Gln Gln Leu Asp Lys Ala Lys Glu Ala Val 
465                 470                 475                 480


Ala Glu Ala Glu Arg His Asp Pro Arg Asn Val Phe Thr Gln Phe Tyr 
                485                 490                 495


Ile Phe Lys Ile Ala Val Ile Glu Gly Asn Ser Glu Arg Ala Leu Gln 
            500                 505                 510


Ala Ile Ile Thr Leu Glu Asn Ile Leu Thr Asp Glu Glu Ser Glu Asp 
        515                 520                 525


Asn Asp Leu Val Ala Glu Arg Gly Ser Pro Thr Met Leu Leu Ser Leu 
    530                 535                 540


Ala Ala Gln Phe Ala Leu Glu Asn Gly Gln Gln Ile Val Ala Glu Lys 
545                 550                 555                 560


Ala Leu Glu Tyr Leu Ala Gln His Ser Glu Asp Gln Glu Gln Val Leu 
                565                 570                 575


Thr Ala Val Lys Cys Leu Leu Arg Phe Leu Leu Pro Lys Ile Ala Glu 
            580                 585                 590


Met Pro Glu Ser Glu Asp Lys Lys Lys Glu Met Asp Arg Leu Leu Thr 
        595                 600                 605


Cys Leu Asn Arg Ala Phe Val Lys Leu Ser Gln Pro Phe Gly Glu Glu 
    610                 615                 620


Ala Leu Ser Leu Glu Ser Arg Ala Asn Glu Ala Gln Trp Phe Arg Lys 
625                 630                 635                 640


Thr Ala Trp Asn Leu Ala Val Gln Cys Asp Lys Asp Pro Val Met Met 
                645                 650                 655


Arg Glu Phe Phe Ile Leu Ser Tyr Lys Met Ser Gln Phe Cys Pro Ser 
            660                 665                 670


Asp Gln Val Ile Leu Ile Ala Arg Lys Thr Cys Leu Leu Met Ala Val 
        675                 680                 685


Ala Val Asp Leu Glu Gln Gly Arg Lys Ala Ser Thr Ala Phe Glu Gln 
    690                 695                 700


Thr Met Phe Leu Ser Arg Ala Leu Glu Glu Ile Gln Thr Cys Asn Asp 
705                 710                 715                 720


Ile His Asn Phe Leu Lys Gln Thr Gly Thr Phe Ser Asn Asp Ser Cys 
                725                 730                 735


Glu Lys Leu Leu Leu Leu Tyr Glu Phe Glu Val Arg Ala Lys Leu Asn 
            740                 745                 750


Asp Pro Leu Leu Glu Ser Phe Leu Glu Ser Val Trp Glu Leu Pro His 
        755                 760                 765


Leu Glu Thr Lys Thr Phe Glu Thr Ile Ala Ile Ile Ala Met Glu Lys 
    770                 775                 780


Pro Ala His Tyr Pro Leu Ile Ala Leu Lys Ala Leu Lys Lys Ala Leu 
785                 790                 795                 800


Leu Leu Tyr Lys Lys Glu Glu Pro Ile Asp Ile Ser Gln Tyr Ser Lys 
                805                 810                 815


Cys Met His Asn Leu Val Asn Leu Ser Val Pro Asp Gly Ala Ser Asn 
            820                 825                 830


Val Glu Leu Cys Pro Leu Glu Glu Val Trp Gly Tyr Phe Glu Asp Ala 
        835                 840                 845


Leu Ser His Ile Ser Arg Thr Lys Asp Tyr Pro Glu Met Glu Ile Leu 
    850                 855                 860


Trp Leu Met Val Lys Ser Trp Asn Thr Gly Val Leu Met Phe Ser Arg 
865                 870                 875                 880


Ser Lys Tyr Ala Ser Ala Glu Lys Trp Cys Gly Leu Ala Leu Arg Phe 
                885                 890                 895


Leu Asn His Leu Thr Ser Phe Lys Glu Ser Tyr Glu Thr Gln Met Asn 
            900                 905                 910


Met Leu Tyr Ser Gln Leu Val Glu Ala Leu Ser Asn Asn Lys Gly Pro 
        915                 920                 925


Val Phe His Glu His Gly Tyr Trp Ser Lys Ser Asp 
    930                 935                 940


<210>  10589
<211>  3033
<212>  DNA
<213>  Homo sapiens

<400>  10589
ggagttttct gaacgtcctc gtgcgctgtg gacggaggtt gtggagagag cagggcggca     60

ttggtggctg cggctgaggc ttgagccaga gatttaaaaa tggacaatga tgattttttt    120

tccatggact ttaaagaagt tgttgaaaac ctggttacaa atgataattc acctaacata    180

ccagaggcaa ttgatagact cttcagcgac atagcaaata tcaacaggga gtctatggct    240

gaaataacag acattcagat tgaagaaatg gcagtaaacc tatggaactg ggcacttacc    300

ataggaggag gttggcttgt aaatgaagag cagaaaatta gattacatta tgttgcttgc    360

aagttgctga gtatgtgtga agcctcattt gcctcagaac aaagtattca acgactgatt    420

atgatgaata tgagaatagg aaaagaatgg ttggatgctg gaaattttct aatcgctgat    480

gaatgttttc aagctgctgt ggccagtctg gagcaattat acgtcaaatt aattcaaagg    540

agctcccctg aggctgactt gaccatggag aagattactg ttgagagtga ccacttcaga    600

gtgctttctt accaagcaga gtcagcagtt gctcaagggg attttcaaag agcatctatg    660

tgtgtactgc aatgtaaaga tatgttgatg aggctccccc agatgacttc aagtcttcat    720

catctctgtt acaactttgg agtagaaacc cagaagaata ataaatatga agaaagttct    780

ttctggctta gccaaagcta tgatattggg aagatggata agaaatctac tgggccagaa    840

atgctggcta aagttctacg gctattagcc acgaattatt tggattggga tgacaccaaa    900

tattatgata aggctctcaa tgctgtaaac ctagcaaaca aggaacattt aagttctcct    960

gggcttttct taaaaatgaa aatcctcttg aaaggcgaaa catctaatga agaactcctt   1020

gaagctgtca tggaaatact acatcttgac atgcccttag acttctgtct gaacattgct   1080

aaactgctga tggatcatga aagagaatct gttgggtttc atttcctgac gattattcat   1140

gaacgtttta agtcatcgga aaatattgga aaagttctga tactccatac tgacatgctt   1200

ttacaaagga aggaagaact tcttgccaag gagaagattg aagaaatctt tttagctcac   1260

caaacaggaa gacaactgac agcagaatca atgaactggt tacacaacat tctgtggaga   1320

caagctgcca gtagttttga ggtacaaaat tacactgatg ccctacaatg gtactattat   1380

tctctgaggt tttattcaac tgatgaaatg gatctggact tcaccaagct gcagaggaac   1440

atggcttgct gttacctgaa tttgcaacaa cttgataagg ccaaagaggc agtggcagaa   1500

gctgaacgac atgaccctag gaacgttttc actcaatttt atatattcaa gattgcagtc   1560

atagagggca actctgaaag agctttgcag gcaataatta ctttagagaa tatattaaca   1620

gatgaagagt cagaagataa tgatctagtt gcagagagag gttcacctac catgcttcta   1680

agtttagctg cccagtttgc tctagagaat ggacaacaaa ttgtggcaga aaaagctttg   1740

gaatatttag ctcaacattc agaagaccag gaacaagttc ttacagctgt aaagtgtttg   1800

cttcgttttc ttcttccaaa aattgctgaa atgccggaat ctgaagataa gaagaaagaa   1860

atggatcgac ttttgacttg cctgaataga gcctttgtga aactttctca gccttttggt   1920

gaagaagcct taagtttgga gtcaagagct aatgaagctc agtggtttcg aaaaacagct   1980

tggaacttgg ctgtgcaatg tgacaaagat ccagtgatga tgagagagtt ttttatactt   2040

tcttataaga tgtcccagtt ttgtccttct gatcaagtaa ttctgattgc acggaaaaca   2100

tgtttactta tggcagttgc agttgatcta gagcaaggga gaaaagcttc aacagctttt   2160

gaacagacca tgttcctgag tcgtgcactt gaggagatcc agacatgcaa tgacatccat   2220

aatttcctga aacaaacagg gaccttctca aatgattcat gtgagaaatt gcttctgctg   2280

tacgagtttg aagttagagc caaattgaat gatccattac tggaaagctt cctggaatca   2340

gtgtgggagt tgcctcattt agaaactaaa acttttgaaa caattgcaat aatagcaatg   2400

gaaaagcctg cacactatcc tttgattgct ctcaaggcct tgaaaaaggc tttattgctc   2460

tacaaaaagg aagaaccaat tgatatatca caatacagca aatgtatgca caacttggtt   2520

aacctctcag tgccagatgg ggcgtcgaat gtagagctct gtcccctgga agaagtttgg   2580

ggctattttg aagatgctct gagccacatt agccgcacta aagactaccc agaaatggag   2640

attctctggc tgatggtcaa gtcctggaat accggagtac ttatgtttag caggagcaag   2700

tatgcatctg ctgaaaagtg gtgtggcctg gccttgcgtt tccttaacca ccttacctcc   2760

ttcaaggaaa gctatgaaac tcagatgaat atgctgtata gtcagcttgt ggaagcattg   2820

agtaacaaca agggcccagt ttttcatgaa catggctact ggagcaagtc agattaggca   2880

agctcatggc cacatgaaga agatacattg tcccgagatg ctgactgttt aaatttttgc   2940

cagagtttct cttgagcttt tgtttctgtt tgctcagacc ctgttttcat gttgttgaat   3000

aaactttcta aaataaaagc atgctgaatt tac                                3033


<210>  10590
<211>  925
<212>  PRT
<213>  Homo sapiens

<400>  10590

Met Asp Asn Asp Asp Phe Phe Ser Met Asp Phe Lys Glu Val Val Glu 
1               5                   10                  15


Asn Leu Val Thr Asn Asp Asn Ser Pro Asn Ile Pro Glu Ala Ile Asp 
            20                  25                  30


Arg Leu Phe Ser Asp Ile Ala Asn Ile Asn Arg Glu Ser Met Ala Glu 
        35                  40                  45


Ile Thr Asp Ile Gln Ile Glu Glu Met Ala Val Asn Leu Trp Asn Trp 
    50                  55                  60


Ala Leu Thr Ile Gly Gly Gly Trp Leu Val Asn Glu Glu Gln Lys Ile 
65                  70                  75                  80


Arg Leu His Tyr Val Ala Cys Lys Leu Leu Ser Met Cys Glu Ala Ser 
                85                  90                  95


Phe Ala Ser Glu Gln Ser Ile Gln Arg Leu Ile Met Met Asn Met Arg 
            100                 105                 110


Ile Gly Lys Glu Trp Leu Asp Ala Gly Asn Phe Leu Ile Ala Asp Glu 
        115                 120                 125


Cys Phe Gln Ala Ala Val Ala Ser Leu Glu Gln Leu Tyr Val Lys Leu 
    130                 135                 140


Ile Gln Arg Ser Ser Pro Glu Ala Asp Leu Thr Met Glu Lys Ile Thr 
145                 150                 155                 160


Val Glu Ser Asp His Phe Arg Val Leu Ser Tyr Gln Ala Glu Ser Ala 
                165                 170                 175


Val Ala Gln Gly Asp Phe Gln Arg Ala Ser Met Cys Val Leu Gln Cys 
            180                 185                 190


Lys Asp Met Leu Met Arg Leu Pro Gln Met Thr Ser Ser Leu His His 
        195                 200                 205


Leu Cys Tyr Asn Phe Gly Val Glu Thr Gln Lys Asn Asn Lys Tyr Glu 
    210                 215                 220


Glu Ser Ser Phe Trp Leu Ser Gln Ser Tyr Asp Ile Gly Lys Met Asp 
225                 230                 235                 240


Lys Lys Ser Thr Gly Pro Glu Met Leu Ala Lys Val Leu Arg Leu Leu 
                245                 250                 255


Ala Thr Asn Tyr Leu Asp Trp Asp Asp Thr Lys Tyr Tyr Asp Lys Ala 
            260                 265                 270


Leu Asn Ala Val Asn Leu Ala Asn Lys Glu His Leu Ser Ser Pro Gly 
        275                 280                 285


Leu Phe Leu Lys Met Lys Ile Leu Leu Lys Gly Glu Thr Ser Asn Glu 
    290                 295                 300


Glu Leu Leu Glu Ala Val Met Glu Ile Leu His Leu Asp Met Pro Leu 
305                 310                 315                 320


Asp Phe Cys Leu Asn Ile Ala Lys Leu Leu Met Asp His Glu Arg Glu 
                325                 330                 335


Ser Val Gly Phe His Phe Leu Thr Ile Ile His Glu Arg Phe Lys Ser 
            340                 345                 350


Ser Glu Asn Ile Gly Lys Val Leu Ile Leu His Thr Asp Met Leu Leu 
        355                 360                 365


Gln Arg Lys Glu Glu Leu Leu Ala Lys Glu Lys Ile Glu Glu Ile Phe 
    370                 375                 380


Leu Ala His Gln Thr Gly Arg Gln Leu Thr Ala Glu Ser Met Asn Trp 
385                 390                 395                 400


Leu His Asn Ile Leu Trp Arg Gln Ala Ala Ser Ser Phe Glu Val Gln 
                405                 410                 415


Asn Tyr Thr Asp Ala Leu Gln Trp Tyr Tyr Tyr Ser Leu Arg Phe Tyr 
            420                 425                 430


Ser Thr Asp Glu Met Asp Leu Asp Phe Thr Lys Leu Gln Arg Asn Met 
        435                 440                 445


Ala Cys Cys Tyr Leu Asn Leu Gln Gln Leu Asp Lys Ala Lys Glu Ala 
    450                 455                 460


Val Ala Glu Ala Glu Arg His Asp Pro Arg Asn Val Phe Thr Gln Phe 
465                 470                 475                 480


Tyr Ile Phe Lys Ile Ala Val Ile Glu Gly Asn Ser Glu Arg Ala Leu 
                485                 490                 495


Gln Ala Ile Ile Thr Leu Glu Asn Ile Leu Thr Asp Glu Glu Ser Glu 
            500                 505                 510


Asp Asn Asp Leu Val Ala Glu Arg Gly Ser Pro Thr Met Leu Leu Ser 
        515                 520                 525


Leu Ala Ala Gln Phe Ala Leu Glu Asn Gly Gln Gln Ile Val Ala Glu 
    530                 535                 540


Lys Ala Leu Glu Tyr Leu Ala Gln His Ser Glu Asp Gln Glu Gln Val 
545                 550                 555                 560


Leu Thr Ala Val Lys Cys Leu Leu Arg Phe Leu Leu Pro Lys Ile Ala 
                565                 570                 575


Glu Met Pro Glu Ser Glu Asp Lys Lys Lys Glu Met Asp Arg Leu Leu 
            580                 585                 590


Thr Cys Leu Asn Arg Ala Phe Val Lys Leu Ser Gln Pro Phe Gly Glu 
        595                 600                 605


Glu Ala Leu Ser Leu Glu Ser Arg Ala Asn Glu Ala Gln Trp Phe Arg 
    610                 615                 620


Lys Thr Ala Trp Asn Leu Ala Val Gln Cys Asp Lys Asp Pro Val Met 
625                 630                 635                 640


Met Arg Glu Phe Phe Ile Leu Ser Tyr Lys Met Ser Gln Phe Cys Pro 
                645                 650                 655


Ser Asp Gln Val Ile Leu Ile Ala Arg Lys Thr Cys Leu Leu Met Ala 
            660                 665                 670


Val Ala Val Asp Leu Glu Gln Gly Arg Lys Ala Ser Thr Ala Phe Glu 
        675                 680                 685


Gln Thr Met Phe Leu Ser Arg Ala Leu Glu Glu Ile Gln Thr Cys Asn 
    690                 695                 700


Asp Ile His Asn Phe Leu Lys Gln Thr Gly Thr Phe Ser Asn Asp Ser 
705                 710                 715                 720


Cys Glu Lys Leu Leu Leu Leu Tyr Glu Phe Glu Val Arg Ala Lys Leu 
                725                 730                 735


Asn Asp Pro Leu Leu Glu Ser Phe Leu Glu Ser Val Trp Glu Leu Pro 
            740                 745                 750


His Leu Glu Thr Lys Thr Phe Glu Thr Ile Ala Ile Ile Ala Met Glu 
        755                 760                 765


Lys Pro Ala His Tyr Pro Leu Ile Ala Leu Lys Ala Leu Lys Lys Ala 
    770                 775                 780


Leu Leu Leu Tyr Lys Lys Glu Glu Pro Ile Asp Ile Ser Gln Tyr Ser 
785                 790                 795                 800


Lys Cys Met His Asn Leu Val Asn Leu Ser Val Pro Asp Gly Ala Ser 
                805                 810                 815


Asn Val Glu Leu Cys Pro Leu Glu Glu Val Trp Gly Tyr Phe Glu Asp 
            820                 825                 830


Ala Leu Ser His Ile Ser Arg Thr Lys Asp Tyr Pro Glu Met Glu Ile 
        835                 840                 845


Leu Trp Leu Met Val Lys Ser Trp Asn Thr Gly Val Leu Met Phe Ser 
    850                 855                 860


Arg Ser Lys Tyr Ala Ser Ala Glu Lys Trp Cys Gly Leu Ala Leu Arg 
865                 870                 875                 880


Phe Leu Asn His Leu Thr Ser Phe Lys Glu Ser Tyr Glu Thr Gln Met 
                885                 890                 895


Asn Met Leu Tyr Ser Gln Leu Val Glu Ala Leu Ser Asn Asn Lys Gly 
            900                 905                 910


Pro Val Phe His Glu His Gly Tyr Trp Ser Lys Ser Asp 
        915                 920                 925


<210>  10591
<211>  752
<212>  DNA
<213>  Homo sapiens

<400>  10591
cacccagaga atctctctgc accacgtatt ccagctggag gtggcgtcag caattctgga     60

ctgctttttc tatcttttca gtgcctcatt cagtgatgtc aagttaaaac cagaaacgat    120

gggtgttcac cagatttttg gttcttatga agggacatgg atggagctgg aaacacttat    180

gctcagcaaa ctaatgcagg aacagaaaac caagaaccac atattctcac ttataagtgg    240

gagctaaaca atgagaaaac atggacacat gtgggggaac aaaacatacc ggggcctgtt    300

gcagaagcag gcagggtgag ggagagcatc gggaagaaca gctaatggat gctgggctta    360

atacctaggt gatgggttga tctgtgcagc acatcaccgt ggcacatgtt tacctatgtc    420

acaaacctgc acatcctgca cctgtacccc tgaacttaaa agttgaagaa gaaaaaataa    480

atttgcatat agtaattttt aggatacact gttagggtca atacatttca tacggtttta    540

acgtatggct catcttaccc tacaaggaat attggaaaat tgtctggggg caaaagagcc    600

tgacctttgt gctgtcatgt tgacaagtct tgtgaggaaa gcggccctgg aaaggcacgt    660

gcctctgtgc aaattacttt ccagcagagg taattcccat agaggctaat agttaaaggc    720

tttgtgccaa gcctcactcc acacagctag ag                                  752


<210>  10592
<211>  42
<212>  PRT
<213>  Homo sapiens

<400>  10592

Met Gly Val His Gln Ile Phe Gly Ser Tyr Glu Gly Thr Trp Met Glu 
1               5                   10                  15


Leu Glu Thr Leu Met Leu Ser Lys Leu Met Gln Glu Gln Lys Thr Lys 
            20                  25                  30


Asn His Ile Phe Ser Leu Ile Ser Gly Ser 
        35                  40


<210>  10593
<211>  655
<212>  DNA
<213>  Homo sapiens

<400>  10593
aagaccggca ggcaggctgc aggcagcgga taggacacag agacagacag acagacacac     60

gcgcggggga tcgaagaccg cccagatacc caagatgccc actggataga gtgattaacc    120

atccctgtta atgtggaaca gagaggtttc ctgggatact ggactttcag tggtaaaagt    180

tggaaagtct aagctggctg gcaaaatgta ataatgtgaa agaagaaaac tctaggaaga    240

aacttcaaca gtaaaatgaa ataaaatact aagaggattt tcaggaaacg ctgtttggaa    300

ggcagaaggg agacgggaca aatagcaaga ttttaaagtg aagaggccgg cccaatatag    360

gccctcggga gctggaaagg aaggccacct agtggcgttt gagcgaagga cacagcttat    420

ctgcagttaa taaccggcag agaaagagca gaaggatata agaacatcaa cttaatttcc    480

caacttcact gtgatctgcc tatcaaccca cacccatgga acaatcctaa tcagaagaca    540

caaggggctc cagggccttt ggccacagac tgaaggcggc actatcagct tccctacttt    600

tgaggttttg ggactcagac tgatccacca ctggcttcct tgctcctcaa cttgc         655


<210>  10594
<211>  59
<212>  PRT
<213>  Homo sapiens

<400>  10594

Phe Pro Asn Phe Thr Val Ile Cys Leu Ser Thr His Thr His Gly Thr 
1               5                   10                  15


Ile Leu Ile Arg Arg His Lys Gly Leu Gln Gly Leu Trp Pro Gln Thr 
            20                  25                  30


Glu Gly Gly Thr Ile Ser Phe Pro Thr Phe Glu Val Leu Gly Leu Arg 
        35                  40                  45


Leu Ile His His Trp Leu Pro Cys Ser Ser Thr 
    50                  55


<210>  10595
<211>  1949
<212>  DNA
<213>  Homo sapiens

<400>  10595
agaggaagcg ggaagttact tagcacggtt ccgggtttct cgcgccccgc ctgtcccccc     60

tccctatcac tgctactggc tcttggtccc tccgttggac tgtcctgcgg agagaaaccc    120

cagcccatcg gtctgcgctg ggaccgcccg ccgcgcatct gcccttcttc gctgactccg    180

ccccgcatct ggccagaccc gcctcgcgtc agagctgacc cactcactgc gcgtttgcca    240

gtcagtctct ccggacctgc ctcgagcctc aggctgctga aatcaccgcg cctcactcgc    300

ctggccgctg ccaatagagc catctggcac atgaatggag tgcggctcaa caaccgccag    360

gtgtatgttg gcagattcaa attcccagaa gagcgggcgg ctgaggtcag aaccagggat    420

agagcaactt tcaccaatgt tttcgttaaa aacattggag acgacataga tgacgaaaaa    480

ctgaaggaac ttttctgtga atatgggcca actgagagtg ttaaagtaat aagagatgcc    540

agtgggaaat ctaaaggctt tggatttgtg agatatgaga cacacgaggc tgcccaaaag    600

gctgtgctag acttgcatgg aaagtccatc gatggaaaag tcctctatgt agggcgagca    660

cagaagaaaa ttgaacgcct ggctgagttg aggcggagat ttgaacggct gaggttaaaa    720

gaaaaaagtc ggcccccagg ggtgcctatc tatattaaga acttggatga gacaatcaat    780

gatgaaaaac tgaaggagga attttcttcc tttgggtcaa ttagtcgggc caaagtgatg    840

atggaagtgg ggcaaggcaa aggatttggt gtggtctgct tttcctcttt tgaagaggct    900

accaaagcag tggatgagat gaatggccgc atagtgggct ccaagcccct gcatgtcacc    960

ctgggccagg ccaggcgcag gtgctgagaa taagaatgct cagtttgttt cagccttagt   1020

tggtgcctcc ttagtttggg ctcctttgtg ataaggggtt attttatgct aattcacaag   1080

tttttttttg aagtgaattc ttttgaaaaa aaaatgcaaa actagaaaac tttattcatt   1140

ttagaataga acataatttc taactgtaaa attgtcattt tgtacttttt ttgatgtaat   1200

atccttagaa atctgtagaa taaagtgtat tcctccactt ttttttcctg aacagtcaag   1260

gtgaggcaat tgattgagta tatttccctt cttatttcag taatactcta ttttttttca   1320

tgaaaatgtc aacatggttc ttctgaatct atcacagtga aaagttctaa cttgtttttg   1380

agaagtcagt acagcagggg aaaacatatg tgatgcaatt aacatctgca taatttcact   1440

taaaattatt atgcaaaaat gaatgttttt tcaaaaaatg tgaaatgtat tttattttct   1500

ttatttgtat tcttgtttca ttttttaata tgttgtgaac atgctacaga tttgatagta   1560

cttttgacta aatgttggga gtggtcgtat taacttcttg cccaaagaag taagcatatt   1620

ggtgttttct caattagtca ctgagaaaat taacacttta ggcagtggct atttaaagta   1680

ggaattgcat cttaaaaacc tttcctaaga gatttggtat gtgaggatac tttcagtacc   1740

actcctacca ttcatttttc taaattcctt agtacatata cttggatcat gttaaattaa   1800

caagaaagat gaataactgc gctgaattgc ctttacctat aaataattta atattttacc   1860

ttcgggtttt atcaactgtc aatataaaag gcagtactcc acagaatgat gttgaaaaac   1920

ttcttcgaag aacaccttct attaaactt                                     1949


<210>  10596
<211>  218
<212>  PRT
<213>  Homo sapiens

<400>  10596

Met Asn Gly Val Arg Leu Asn Asn Arg Gln Val Tyr Val Gly Arg Phe 
1               5                   10                  15


Lys Phe Pro Glu Glu Arg Ala Ala Glu Val Arg Thr Arg Asp Arg Ala 
            20                  25                  30


Thr Phe Thr Asn Val Phe Val Lys Asn Ile Gly Asp Asp Ile Asp Asp 
        35                  40                  45


Glu Lys Leu Lys Glu Leu Phe Cys Glu Tyr Gly Pro Thr Glu Ser Val 
    50                  55                  60


Lys Val Ile Arg Asp Ala Ser Gly Lys Ser Lys Gly Phe Gly Phe Val 
65                  70                  75                  80


Arg Tyr Glu Thr His Glu Ala Ala Gln Lys Ala Val Leu Asp Leu His 
                85                  90                  95


Gly Lys Ser Ile Asp Gly Lys Val Leu Tyr Val Gly Arg Ala Gln Lys 
            100                 105                 110


Lys Ile Glu Arg Leu Ala Glu Leu Arg Arg Arg Phe Glu Arg Leu Arg 
        115                 120                 125


Leu Lys Glu Lys Ser Arg Pro Pro Gly Val Pro Ile Tyr Ile Lys Asn 
    130                 135                 140


Leu Asp Glu Thr Ile Asn Asp Glu Lys Leu Lys Glu Glu Phe Ser Ser 
145                 150                 155                 160


Phe Gly Ser Ile Ser Arg Ala Lys Val Met Met Glu Val Gly Gln Gly 
                165                 170                 175


Lys Gly Phe Gly Val Val Cys Phe Ser Ser Phe Glu Glu Ala Thr Lys 
            180                 185                 190


Ala Val Asp Glu Met Asn Gly Arg Ile Val Gly Ser Lys Pro Leu His 
        195                 200                 205


Val Thr Leu Gly Gln Ala Arg Arg Arg Cys 
    210                 215


<210>  10597
<211>  3446
<212>  DNA
<213>  Homo sapiens

<400>  10597
aggaagcggg aagttactta gcacggttcc gggtttctcg cgccccgcct gtcccccctc     60

cctatcactg ctactggctc ttggtccctc cgttggactg tcctgcggag agaaacccca    120

gcccatcggt ctgcgctggg accgcccgcc gcgcatctgc ccttcttcgc tgactccgcc    180

ccgcatctgg ccagacccgc ctcgcgtcag agctgaccca ctcactgcgc gtttgccagt    240

cagtctctcc ggacctgcct cgagcctcag gctgctgaaa tcaccgcgcc tcactcgcct    300

cgacagtgat tctgagtctg cttttagctt ccttttgcct gccttggctt tttctgttcg    360

tgaacagctg tttggcccat agcttagaga aagcagcctt ttttctcttc aaagagaacc    420

tcctcccagt gctcagagag atggggagcg gggagcctaa tcctgctggc aagaaaaaga    480

agtatctcaa ggccgctctg tacgtgggtg acttggaccc agatgtcacc gaggacatgc    540

tctataagaa gttcaggcct gctggccctc tgcgattcac ccgaatctgc cgtgatccgg    600

tgacccgcag ccccctgggc tatgggtatg ttaacttccg ctttcccgcg gatgcagagt    660

gggccttgaa caccatgaat tttgatttga ttaatggaaa accattccgc cttatgtggt    720

ctcagccaga tgaccgctta agaaagtctg gagtgggaaa tatattcatc aaaaacctgg    780

acaaatccat agacaatagg gccctgtttt acttattttc tgcttttggg aacattctgt    840

cctgcaaagt cgtatgcgat gacaacggct ctaagggtta tgcctatgtt cactttgaca    900

gcctggccgc tgccaataga gccatctggc acatgaatgg agtgcggctc aacaaccgcc    960

aggtgtatgt tggcagattc aaattcccag aagagcgggc ggctgaggtc agaaccaggg   1020

atagagcaac tttcaccaat gttttcgtta aaaacattgg agacgacata gatgacgaaa   1080

aactgaagga acttttctgt gaatatgggc caactgagag tgttaaagta ataagagatg   1140

ccagtgggaa atctaaaggc tttggatttg tgagatatga gacacacgag gctgcccaaa   1200

aggctgtgct agacttgcat ggaaagtcca tcgatggaaa agtcctctat gtagggcgag   1260

cacagaagaa aattgaacgc ctggctgagt tgaggcggag atttgaacgg ctgaggttaa   1320

aagaaaaaag tcggccccca ggggtgccta tctatattaa gaacttggat gagacaatca   1380

atgatgaaaa actgaaggag gaattttctt cctttgggtc aattagtcgg gccaaagtga   1440

tgatggaagt ggggcaaggc aaaggatttg gtgtggtctg cttttcctct tttgaagagg   1500

ctaccaaagc agtggatgag atgaatggcc gcatagtggg ctccaagccc ctgcatgtca   1560

ccctgggcca ggccaggcgc aggtgctgag aataagaatg ctcagtttgt ttcagcctta   1620

gttggtgcct ccttagtttg ggctcctttg tgataagggg ttattttatg ctaattcaca   1680

agtttttttt tgaagtgaat tcttttgaaa aaaaaatgca aaactagaaa actttattca   1740

ttttagaata gaacataatt tctaactgta aaattgtcat tttgtacttt ttttgatgta   1800

atatccttag aaatctgtag aataaagtgt attcctccac ttttttttcc tgaacagtca   1860

aggtgaggca attgattgag tatatttccc ttcttatttc agtaatactc tatttttttt   1920

catgaaaatg tcaacatggt tcttctgaat ctatcacagt gaaaagttct aacttgtttt   1980

tgagaagtca gtacagcagg ggaaaacata tgtgatgcaa ttaacatctg cataatttca   2040

cttaaaatta ttatgcaaaa atgaatgttt tttcaaaaaa tgtgaaatgt attttatttt   2100

ctttatttgt attcttgttt cattttttaa tatgttgtga acatgctaca gatttgatag   2160

tacttttgac taaatgttgg gagtggtcgt attaacttct tgcccaaaga agtaagcata   2220

ttggtgtttt ctcaattagt cactgagaaa attaacactt taggcagtgg ctatttaaag   2280

taggaattgc atcttaaaaa cctttcctaa gagatttggt atgtgaggat actttcagta   2340

ccactcctac cattcatttt tctaaattcc ttagtacata tacttggatc atgttaaatt   2400

aacaagaaag atgaataact gcgctgaatt gcctttacct ataaataatt taatatttta   2460

ccttcgggtt ttatcaactg tcaatataaa aggcagtact ccacagaatg atgttgaaaa   2520

acttcttcga agaacacctt ctattaaact tgttatctct tgtaaattat tgtgtgtgtc   2580

cttttgataa tattcacagg tgtttcaaag gtaaggaata ggttgtctct tggattaagt   2640

catatgcctc cagccattat atgagaactg tgaaaccaat atggttttct ttatgtcttg   2700

gctgcttgaa aattaaaaaa aaaaaaggtt tgttcaatat tgccgttaca tttattagcc   2760

tgtaatttct aaattggaga ttctctacat ttcacttgca gtttcctgtt ctcctcattg   2820

cctgccttcc attcatatta cacttatttt tctatttttt gtattacctt tttaaaaata   2880

tataccagtt caagtccttt taggaagaag aaaataccta atttatgtaa aatttaaata   2940

attacttttt tataatatga ttcacttatg ccacagattc aacattagaa tatgttttat   3000

ctctactgtc agttttatta ccttatatac aaatcttcat tttcatacat agtacaatgt   3060

aaatatataa ctttgttaac acttttgtta gctctttgac cataaaataa tgacaataag   3120

ctgtttctat gtatttgttt atctacaaat tacaggttta tccatttgca aatattttca   3180

aaatggaaat cactgtttat attgattata aacataagac atgctcattg taaaaaatgt   3240

acacaaggca gaaggaagta aaatttccac agttcagaaa taccacaatt aatattttca   3300

atgtgtaaat atcttttcat aatttttcct acgtatacac aaacattttg accaaaaatc   3360

cacactatat gtactgttct gtatttttaa ttttaaactg aacaataatc atcttttcct   3420

gacaataaat atcaatctct atcatc                                        3446


<210>  10598
<211>  382
<212>  PRT
<213>  Homo sapiens

<400>  10598

Met Gly Ser Gly Glu Pro Asn Pro Ala Gly Lys Lys Lys Lys Tyr Leu 
1               5                   10                  15


Lys Ala Ala Leu Tyr Val Gly Asp Leu Asp Pro Asp Val Thr Glu Asp 
            20                  25                  30


Met Leu Tyr Lys Lys Phe Arg Pro Ala Gly Pro Leu Arg Phe Thr Arg 
        35                  40                  45


Ile Cys Arg Asp Pro Val Thr Arg Ser Pro Leu Gly Tyr Gly Tyr Val 
    50                  55                  60


Asn Phe Arg Phe Pro Ala Asp Ala Glu Trp Ala Leu Asn Thr Met Asn 
65                  70                  75                  80


Phe Asp Leu Ile Asn Gly Lys Pro Phe Arg Leu Met Trp Ser Gln Pro 
                85                  90                  95


Asp Asp Arg Leu Arg Lys Ser Gly Val Gly Asn Ile Phe Ile Lys Asn 
            100                 105                 110


Leu Asp Lys Ser Ile Asp Asn Arg Ala Leu Phe Tyr Leu Phe Ser Ala 
        115                 120                 125


Phe Gly Asn Ile Leu Ser Cys Lys Val Val Cys Asp Asp Asn Gly Ser 
    130                 135                 140


Lys Gly Tyr Ala Tyr Val His Phe Asp Ser Leu Ala Ala Ala Asn Arg 
145                 150                 155                 160


Ala Ile Trp His Met Asn Gly Val Arg Leu Asn Asn Arg Gln Val Tyr 
                165                 170                 175


Val Gly Arg Phe Lys Phe Pro Glu Glu Arg Ala Ala Glu Val Arg Thr 
            180                 185                 190


Arg Asp Arg Ala Thr Phe Thr Asn Val Phe Val Lys Asn Ile Gly Asp 
        195                 200                 205


Asp Ile Asp Asp Glu Lys Leu Lys Glu Leu Phe Cys Glu Tyr Gly Pro 
    210                 215                 220


Thr Glu Ser Val Lys Val Ile Arg Asp Ala Ser Gly Lys Ser Lys Gly 
225                 230                 235                 240


Phe Gly Phe Val Arg Tyr Glu Thr His Glu Ala Ala Gln Lys Ala Val 
                245                 250                 255


Leu Asp Leu His Gly Lys Ser Ile Asp Gly Lys Val Leu Tyr Val Gly 
            260                 265                 270


Arg Ala Gln Lys Lys Ile Glu Arg Leu Ala Glu Leu Arg Arg Arg Phe 
        275                 280                 285


Glu Arg Leu Arg Leu Lys Glu Lys Ser Arg Pro Pro Gly Val Pro Ile 
    290                 295                 300


Tyr Ile Lys Asn Leu Asp Glu Thr Ile Asn Asp Glu Lys Leu Lys Glu 
305                 310                 315                 320


Glu Phe Ser Ser Phe Gly Ser Ile Ser Arg Ala Lys Val Met Met Glu 
                325                 330                 335


Val Gly Gln Gly Lys Gly Phe Gly Val Val Cys Phe Ser Ser Phe Glu 
            340                 345                 350


Glu Ala Thr Lys Ala Val Asp Glu Met Asn Gly Arg Ile Val Gly Ser 
        355                 360                 365


Lys Pro Leu His Val Thr Leu Gly Gln Ala Arg Arg Arg Cys 
    370                 375                 380


<210>  10599
<211>  2337
<212>  DNA
<213>  Homo sapiens

<400>  10599
gcgcgtttgc cagtcagtct ctccggacct gcctcgagcc tcaggctgct gaaatcaccg     60

cgcctcactc gcctcgacag tgattctgag tctgctttta gcttcctttt gcctgccttg    120

gctttttctg ttcgtgaaca gctgtttggc ccatagctta gagaaagcag ccttttttct    180

cttcaaagag aacctcctcc cagtgctcag agagatgggg agcggggagc ctaatcctgc    240

tggcaagaaa aagaagtatc tcaaggccgc tctgtacgtg ggtgacttgg acccagatgt    300

caccgaggac atgctctata agaagttcag gcctgctggc cctctgcgat tcacccgaat    360

ctgccgtgat ccggtgaccc gcagccccct gggctatggg tatgttaact tccgctttcc    420

cgcggatgca gagtgggcct tgaacaccat gaattttgat ttgattaatg gaaaaccatt    480

ccgccttatg tggtctcagc cagatgaccg cttaagaaag tctggagtgg gaaatatatt    540

catcaaaaac ctggacaaat ccatagacaa tagggccctg ttttacttat tttctgcttt    600

tgggaacatt ctgtcctgca aagtcgtatg cgatgacaac ggctctaagg gttatgccta    660

tgttcacttt gacagcctgg ccgctgccaa tagagccatc tggcacatga atggagtgcg    720

gctcaacaac cgccaggtgt atgttggcag attcaaattc ccagaagagc gggcggctga    780

ggtcagaacc agggatagag caactttcac caatgttttc gttaaaaaca ttggagacga    840

catagatgac gaaaaactga aggaactttt ctgtgaatat gggccaactg agagtgttaa    900

agtaataaga gatgccagtg ggaaatctaa aggctttgga tttgtgagat atgagacaca    960

cgaggctgcc caaaaggctg tgctagactt gcatggaaag tccatcgatg gaaaagtcct   1020

ctatgtaggg cgagcacaga agaaaattga acgcctggct gagttgaggc ggagatttga   1080

acggctgagg ttaaaagaaa aaagtcggcc cccaggggtg cctatctata ttaagaactt   1140

ggatgagaca atcaatgatg aaaaactgaa ggaggaattt tcttcctttg ggtcaattag   1200

tcgggccaaa gtgatgatgg aagtggggca aggcaaagga tttggtgtgg tctgcttttc   1260

ctcttttgaa gaggctacca aagcagtgga tgagatgaat ggccgcatag tgggctccaa   1320

gcccctgcat gtcaccctgg gccaggccag gcgcaggtgc tgagaataag aatgctcagt   1380

ttgtttcagc cttagttggt gcctccttag tttgggctcc tttgtgataa ggggttattt   1440

tatgctaatt cacaagtttt tttttgaagt gaattctttt gaaaaaaaaa tgcaaaacta   1500

gaaaacttta ttcattttag aatagaacat aatttctaac tgtaaaattg tcattttgta   1560

ctttttttga tgtaatatcc ttagaaatct gtagaataaa gtgtattcct ccactttttt   1620

ttcctgaaca gtcaaggtga ggcaattgat tgagtatatt tcccttctta tttcagtaat   1680

actctatttt ttttcatgaa aatgtcaaca tggttcttct gaatctatca cagtgaaaag   1740

ttctaacttg tttttgagaa gtcagtacag caggggaaaa catatgtgat gcaattaaca   1800

tctgcataat ttcacttaaa attattatgc aaaaatgaat gttttttcaa aaaatgtgaa   1860

atgtatttta ttttctttat ttgtattctt gtttcatttt ttaatatgtt gtgaacatgc   1920

tacagatttg atagtacttt tgactaaatg ttgggagtgg tcgtattaac ttcttgccca   1980

aagaagtaag catattggtg ttttctcaat tagtcactga gaaaattaac actttaggca   2040

gtggctattt aaagtaggaa ttgcatctta aaaacctttc ctaagagatt tggtatgtga   2100

ggatactttc agtaccactc ctaccattca tttttctaaa ttccttagta catatacttg   2160

gatcatgtta aattaacaag aaagatgaat aactgcgctg aattgccttt acctataaat   2220

aatttaatat tttaccttcg ggttttatca actgtcaata taaaaggcag tactccacag   2280

aatgatgttg aaaaacttct tcgaagaaca ccttctatta aacttgttat ctcttgt      2337


<210>  10600
<211>  382
<212>  PRT
<213>  Homo sapiens

<400>  10600

Met Gly Ser Gly Glu Pro Asn Pro Ala Gly Lys Lys Lys Lys Tyr Leu 
1               5                   10                  15


Lys Ala Ala Leu Tyr Val Gly Asp Leu Asp Pro Asp Val Thr Glu Asp 
            20                  25                  30


Met Leu Tyr Lys Lys Phe Arg Pro Ala Gly Pro Leu Arg Phe Thr Arg 
        35                  40                  45


Ile Cys Arg Asp Pro Val Thr Arg Ser Pro Leu Gly Tyr Gly Tyr Val 
    50                  55                  60


Asn Phe Arg Phe Pro Ala Asp Ala Glu Trp Ala Leu Asn Thr Met Asn 
65                  70                  75                  80


Phe Asp Leu Ile Asn Gly Lys Pro Phe Arg Leu Met Trp Ser Gln Pro 
                85                  90                  95


Asp Asp Arg Leu Arg Lys Ser Gly Val Gly Asn Ile Phe Ile Lys Asn 
            100                 105                 110


Leu Asp Lys Ser Ile Asp Asn Arg Ala Leu Phe Tyr Leu Phe Ser Ala 
        115                 120                 125


Phe Gly Asn Ile Leu Ser Cys Lys Val Val Cys Asp Asp Asn Gly Ser 
    130                 135                 140


Lys Gly Tyr Ala Tyr Val His Phe Asp Ser Leu Ala Ala Ala Asn Arg 
145                 150                 155                 160


Ala Ile Trp His Met Asn Gly Val Arg Leu Asn Asn Arg Gln Val Tyr 
                165                 170                 175


Val Gly Arg Phe Lys Phe Pro Glu Glu Arg Ala Ala Glu Val Arg Thr 
            180                 185                 190


Arg Asp Arg Ala Thr Phe Thr Asn Val Phe Val Lys Asn Ile Gly Asp 
        195                 200                 205


Asp Ile Asp Asp Glu Lys Leu Lys Glu Leu Phe Cys Glu Tyr Gly Pro 
    210                 215                 220


Thr Glu Ser Val Lys Val Ile Arg Asp Ala Ser Gly Lys Ser Lys Gly 
225                 230                 235                 240


Phe Gly Phe Val Arg Tyr Glu Thr His Glu Ala Ala Gln Lys Ala Val 
                245                 250                 255


Leu Asp Leu His Gly Lys Ser Ile Asp Gly Lys Val Leu Tyr Val Gly 
            260                 265                 270


Arg Ala Gln Lys Lys Ile Glu Arg Leu Ala Glu Leu Arg Arg Arg Phe 
        275                 280                 285


Glu Arg Leu Arg Leu Lys Glu Lys Ser Arg Pro Pro Gly Val Pro Ile 
    290                 295                 300


Tyr Ile Lys Asn Leu Asp Glu Thr Ile Asn Asp Glu Lys Leu Lys Glu 
305                 310                 315                 320


Glu Phe Ser Ser Phe Gly Ser Ile Ser Arg Ala Lys Val Met Met Glu 
                325                 330                 335


Val Gly Gln Gly Lys Gly Phe Gly Val Val Cys Phe Ser Ser Phe Glu 
            340                 345                 350


Glu Ala Thr Lys Ala Val Asp Glu Met Asn Gly Arg Ile Val Gly Ser 
        355                 360                 365


Lys Pro Leu His Val Thr Leu Gly Gln Ala Arg Arg Arg Cys 
    370                 375                 380


<210>  10601
<211>  739
<212>  DNA
<213>  Homo sapiens

<400>  10601
ttctccttca ccttccgccg tgattgcaag tttcctgagg cctccccagc catgctgaac     60

tggttctgca ggatatacac gaagtatggc accaacatct gcttctggtg aaggcttcat    120

gaagcttcca cccatgacag aaggcgaaga actgttgcca gcatcatgct acaagcctga    180

agggaaggtc tactgacaga gaaggacaga gaccagggaa acacagaaaa ggagagacaa    240

agccttgaca taccaaacca gtgcctggcc tacctatgga cttctcatgc caacttggga    300

gacatattat caagactgaa tcagagagtt gacagcatac caggaagtgt cactgtatag    360

tttggaagat ggaaatcata ctactttttt cccatgtaag cactccagga aattaacctc    420

caaatacaac tgaggaatag gcaccgttat ggctttttta cagatcaata aactgatgaa    480

atacggtgaa gctatgtaag tagaccaaag atgtacaaga agacacacat tgagcagaaa    540

ataaatttaa gcctggcttc tcaactcttt atttaaccag agacggttct atctcaaaca    600

tgaggttcta tatgaaagca ggagggaatt aggaagtaaa atctggtgag catttttcct    660

gaaatattac agctgtcatt ctcagggccc tcgtcctgag atagtggcag gttaagatat    720

taaattttta tttctctgg                                                 739


<210>  10602
<211>  36
<212>  PRT
<213>  Homo sapiens

<400>  10602

Met Ala Pro Thr Ser Ala Ser Gly Glu Gly Phe Met Lys Leu Pro Pro 
1               5                   10                  15


Met Thr Glu Gly Glu Glu Leu Leu Pro Ala Ser Cys Tyr Lys Pro Glu 
            20                  25                  30


Gly Lys Val Tyr 
        35


<210>  10603
<211>  339
<212>  DNA
<213>  Homo sapiens

<400>  10603
atgcagccag attgctcctt taagtgggtc cctgatctca ttcctcctga actgggacca     60

gtcattccag atagtggtta ttcatcatcc cacgcagagg ccacctatga agaaggcttg    120

gaagtatttg acccctatta tttcatcaaa catgtcccac cactgacaga agaacaacta    180

aataggaaat ctgttcttcc gttgaaaaca agaagcacac cgaaattctc cctagattta    240

cacttggatg aaacagtagt gcactgtagt ctaaatgagg tagaagaggc agcacttact    300

tttccagtcc ttttccaaga tgtcatttat caggtttag                           339


<210>  10604
<211>  112
<212>  PRT
<213>  Homo sapiens

<400>  10604

Met Gln Pro Asp Cys Ser Phe Lys Trp Val Pro Asp Leu Ile Pro Pro 
1               5                   10                  15


Glu Leu Gly Pro Val Ile Pro Asp Ser Gly Tyr Ser Ser Ser His Ala 
            20                  25                  30


Glu Ala Thr Tyr Glu Glu Gly Leu Glu Val Phe Asp Pro Tyr Tyr Phe 
        35                  40                  45


Ile Lys His Val Pro Pro Leu Thr Glu Glu Gln Leu Asn Arg Lys Ser 
    50                  55                  60


Val Leu Pro Leu Lys Thr Arg Ser Thr Pro Lys Phe Ser Leu Asp Leu 
65                  70                  75                  80


His Leu Asp Glu Thr Val Val His Cys Ser Leu Asn Glu Val Glu Glu 
                85                  90                  95


Ala Ala Leu Thr Phe Pro Val Leu Phe Gln Asp Val Ile Tyr Gln Val 
            100                 105                 110


<210>  10605
<211>  6575
<212>  DNA
<213>  Homo sapiens

<400>  10605
cctactacca ggtcattgtg caggagaaca acacgcctgg cgcctatctg ctctctgtgt     60

ctgctcgcga ccccgacctg ggtctcaacg gcagtgtctc ctaccagatc gtgccgtcgc    120

aggtgcggga catgcctgtc ttcacctatg tctccatcaa tcccaactca ggcgacatct    180

acgcgctgcg atcctttaac cacgagcaga ccaaggcgtt cgaattcaag gtgctggcca    240

aggacggcgg ccttccctca ctgcaaagca acgctacggt gcgggtcatc atcctcgacg    300

tcaacgacaa caccccggtc atcacagccc cacctctgat taacggcact gccgaggtct    360

acataccccg caactctggc ataggctacc tggtgactgt tgtcaaggca gaagactacg    420

atgagggcga aaatggccga gtcacctacg acatgaccga gggcgaccgc ggcttctttg    480

aaatagacca ggtcaatggc gaagtcagaa ccacccgcac cttcggggag agctccaagt    540

cctcctatga gcttatcgtg gtggctcacg accacggcaa gacatctctc tctgcctctg    600

ctctcgtcct aatctacttg tcccctgctc tcgatgccca agagtcaatg ggctctgtga    660

acttgtcctt gattttcatt attgccctgg gctccattgc gggcatcctc tttgtaacta    720

tgatcttcgt ggcaatcaag tgcaagcgag acaacaaaga gatccggacc tacaactgca    780

gaattgctga gtactcctat gggcatcaaa agaaatcaag caagaagaaa aaaatcagta    840

agaatgacat ccgcctggta ccccgggatg tggaggagac agacaagatg aacgttgtca    900

gttgctcttc cctgacctcc tccctcaact attttgacta ccaccagcag acgctgcccc    960

tgggctgccg ccgctctgag agcactttcc tgaatgtgga gaaccagaat acccgcaaca   1020

ccagtgctaa ccacatctac catcactctt tcaacagcca ggggccccag cagcctgacc   1080

tgattatcaa cggtgtgcct ctgcctgaga ctgaaaacta ttcttttgac tccaactacg   1140

tgaatagccg agcccattta atcaagagca gctccacctt caaggactta gagggcaaca   1200

gcctgaagga tagtggacat gaggagagtg accaaactga cagtgagcat gatgtccagc   1260

ggagcctgta ttgtgatact gctgtcaacg atgtgctgaa caccagtgtg acctccatgg   1320

gatctcagat gcctgatcat gatcagaatg aaggatttca ttgccgggaa gaatgccgga   1380

ttcttggcca ctctgacagg tgctggatgc cccggaaccc catgcccatc cgttccaagt   1440

cccctgagca tgtgaggaac atcatcgcgc tgtctattga agctactgct gctgatgtcg   1500

aggcttatga cgactgcggc cccaccaaac ggactttcgc aacctttggg aaagatgtca   1560

gcgaccaccc ggctgaggag aggcctaccc tgaaaggcaa gaggactgtc gatgtgacca   1620

tctgcagccc caaggtcaac agcgttatcc gggaggcagg caatggctgt gaggcgatta   1680

gccctgtcac ctcccccctc cacctcaaga gctctctgcc caccaagcct tccgtgtctt   1740

acaccattgc cctggctccc ccagcccgtg atctggagca gtatgtcaac aatgtcaaca   1800

atggccctac tcgtccctct gaagctgagc cccgtggagc tgatagcgag aaagtcatgc   1860

atgaggtcag ccccattctg aaggaaggtc gcaacaaaga gtcccctggt gtgaagcgtc   1920

tgaaggatat cgttctctaa accagtctcc aggaagaaga gaaagaaacc acactggcta   1980

gtgaagaagc aggagcttct tgttttaatt gctcaccaat ggttggttct tgagtggcta   2040

tatttcagag cttttcctaa atgtattgtt tataggtgat tatcattctg tgacagtccc   2100

ttgtttcaac aggcagcagg ggtgttcagt tggagcaaat tagctttggc ttgagttgtt   2160

catggggcct tgatgttggg gaaacagaga caaattcagt tgtgaaaagt attatgtatt   2220

aagtgtttga atttatatat ttttctatgt caaaattata atataaatta ccattgtttg   2280

tggaggatta catttaaaaa agcaaaaagt gaaaaaaaaa agctctggac acctttaata   2340

agctcgccac tgttttttgt agtgtagaca agttaatggt catttattgt gtactattca   2400

ttgattcagt gatgtgaaat tgagccccca aaaggttgtt tctgaagctc gagtacttcc   2460

caatgccgct actttgctgt ggacacccct gctttaaaaa cccttttgct agctgtgcta   2520

ttgttgtatt tgatattgca aattgctatg tgtgtggtga tggcaaaagg cttttaaaag   2580

ttggtgtttt ctttttctta aaaaaataat aaaactacag acaaaaacaa agtgcaaaca   2640

actgagacag caaatgaatg agcaacacca tgcatataga ttgagtactt ggagaatact   2700

cacgtttttt aactcatgta gtgattgctc accactttgc aaagtatttt tcctgccttt   2760

cagtggtctg cccaggtcca tgatagatca ttgcagaaag tcatttttgg ataggctgct   2820

atctaatttg cagttgtcag aaatactgtg ctgaaagttt tatgacatcc atcttttaaa   2880

ttttcaggcc ctgaacagga aagttgctcc tgaagttatg tttccaggct tagaaattcc   2940

ctctctccaa tcatctaaaa ttgaagatga ctgaatctat tttaagatct aaattagcat   3000

ctcttcagac acacacttcc tgattcagtg tttcccaatc atgattagaa ttagactgca   3060

aagcacgtca tgggctggga ttgagaactc catgttgctc tgtatcttag gcttatatac   3120

gtagggatag agtaagcagt acaaagtgta tattttggaa aagacaggta acaggtaaca   3180

gcatcgctaa tccaattact gtgccttcta aacggagaca ctcagacact tgaactcatc   3240

tttttatgac taatagtttt ttgattaaaa atgtgaacaa gaaaatacta aaataaaaat   3300

cctttcgatt tagccaactc tttttgctgt aggctaggaa tacacccttt ttaaattaac   3360

acactgtaga tccttttttt ctgttttaac attcctctaa ctcccccatt tatcttttgt   3420

ctattaatat tcactagcca acatagtatt tttgcagcct aagagttcat tatttaaaaa   3480

taaactaaag aaatatgtca cctttgttct gccttggtct taagagagtt gtttctagag   3540

aaacaagttt tatggttctg ttttcatttg tttcattttt tgaaattcag gaatacacag   3600

agagaaggcc tagaggttag agcactagaa tgcaaaagag gatttatttt cttaagttta   3660

ggtagataag tcagctcttt tgaatgtttt acttattttt gcctgagttc ctagctttac   3720

gcattactag gaatattttc ttttacagga gggagaaggg ttttgaggga gggggtgggt   3780

aaggcagtag ggatggggtt aggtagggga gaacatttct gaaaaagaac ttataatgaa   3840

gctacaaatc catccttatt tcttattcag tgctgaatac tacctcatgc aaaatattgg   3900

tgtggctgca aatttccctc tgaagctgac acaattaagg atgaattacc ataacatctt   3960

catttttcct catttcattg cctctcatac agttttctcc ctctgattta tttcattttg   4020

gtagtggatt ttgaattaag tatttatttc tctttgcaag tgactatttg attaacacat   4080

taaaaatttt ttaaaaattt cccctttaag ttatgatggc tgcctataga atttagactg   4140

tttctcaccc tgatccatcc tgatattatg ttattagcta cgatttcaag gtcactttga   4200

agtcagactt cacagttttc tacaggtgta tttcttgcta tgctcagtgg gaaccaggga   4260

gcagaaaaga ttgtggaaag tgggaacatt aattgtcacg tggctgttga gccagagagg   4320

ccactggctg ccatgcctct taccagccaa gttttaaatg gttagagtgg cattggcatt   4380

gattttgctt ttctcttggg ttttcttcat ttcttttcat aattcatctt caagctatag   4440

atccatcctt cttccctatc caaatacttt gttctcagtg ggcagtcaga tttttttggc   4500

ttccaaacct cactgagcat gttcagagaa ttcctctcat taaggaaata tttttcccca   4560

caattgtctg atgtatgagt cctctcagaa gcacaagtgc atactaggaa ggctttgtaa   4620

actggttttg taggcaggct gtacctgcaa ataggcattc tgagcaagga tcctaaattt   4680

ccctttggct catgtccccc ccgccccacc ccaccttctc ctttttggca tgtctggtga   4740

aaagctacaa ggttcacagg gccaaatatt ctcccttttg ttctctaaac atgttgcaca   4800

cataaactca agggagtgat ttcggttcct aagtcctagg gagttctatt ccatttattc   4860

tgatgtccct tttaaggagg agttggtgtt gaagtgtgac atgctttaat gataactgct   4920

ttggcaattc cccagacagg tatacttctt catccaaaat tgcacctaag gtgttcattt   4980

agacaaaatt gttcgcttag tgatccactg atctctaatc agaaatattt ttaaaaaata   5040

caatttagat ctctgaaaat tggaaccact caagagtatc atcttgatag tgttacttca   5100

gcatatgact gactgatttt atgaagggag tttagctgac ttttccctgt agccctatca   5160

tattaaaaac aaaaagtggt ccacttgaag cagcaaggac aaagggcagt ttagggagag   5220

gcagggtgaa ggggatagct cgattgggca tccagagtgg aaaaggatta ttattgtaca   5280

taatagcagt tctggctgga attccaatcc actttctggg gatcattttg atgttgaatg   5340

ttcccccaaa gcattctgac aagtttggtc cacttggctc tttaccccgg gtaataagac   5400

ccttattgac tttgaaaaac tggcataaat gagcttaaga aatccattgt atacagtcct   5460

agtgtttgcc ttcttggtaa aattacattt aaggatgtca tttcatgagt caaattgtat   5520

ctgctgacac tgaagtgtat tgagatgttg ttctttagtt taagtatgta acaaagtaat   5580

attcaaaggg gatgtttggg ggtggggctg ggaccgggtg gctttatatt gataatgaaa   5640

tattccagag caaaacacat tgtcctaatg aagttgttgc agctctcttc gttttcttgt   5700

gccgctggaa ttggcttgtg ggtcacttgt tgtgcaaaag tgaattaatt tcaaatagga   5760

atcatattgc ttttgtgaaa caaagaaaat ttaccacctt gtctgataca tagattggaa   5820

ggcgctcttg gtaaagaata acccacaaac acctgatctt gattggaaag cattgtaggt   5880

cattagggaa aactgatgat gctgactgtt gctccagctg tgttggcaat tcaagatgac   5940

cttgttacta actgaaagtt gctgtcaacc ttagcaaaca aaccagctaa caccattaca   6000

gcactggtta agtagatttt tactggcact ggctggcgtt cagctgagga aggctaggat   6060

acagacttta atgaccaaga gccagactag ctcgagctag aaatcagcaa caaatacctc   6120

cttgtgctat ttgaatgcta aggtattagt tgcaataggc ttacgccttc gctcctctag   6180

tgaggggaat gagcctgatg acactattac tgtttacctg tcaaaccagg gtggaaattt   6240

agagggatgc aagtacagta tgtctcatta agcagtctct gttgctgatt atatgaagat   6300

aaaattgttg tatatgctga tctgtatgtt atgtacattt tcacagtgat tgaatcattg   6360

taaaaagaaa aaagacaaaa aagaatcacc actgtctatt ttatgaagat gataaagcag   6420

ctttattaaa ttattacagt tatgtttcaa atggtgttat ctgccacatt gtttcctttt   6480

atctggtggt tctctgtttc cccctttaaa tgtgttttct ctgcttcaaa aatttaatgc   6540

attttagtat taaaggctat tatggaaaaa gtatt                              6575


<210>  10606
<211>  602
<212>  PRT
<213>  Homo sapiens

<400>  10606

Met Pro Val Phe Thr Tyr Val Ser Ile Asn Pro Asn Ser Gly Asp Ile 
1               5                   10                  15


Tyr Ala Leu Arg Ser Phe Asn His Glu Gln Thr Lys Ala Phe Glu Phe 
            20                  25                  30


Lys Val Leu Ala Lys Asp Gly Gly Leu Pro Ser Leu Gln Ser Asn Ala 
        35                  40                  45


Thr Val Arg Val Ile Ile Leu Asp Val Asn Asp Asn Thr Pro Val Ile 
    50                  55                  60


Thr Ala Pro Pro Leu Ile Asn Gly Thr Ala Glu Val Tyr Ile Pro Arg 
65                  70                  75                  80


Asn Ser Gly Ile Gly Tyr Leu Val Thr Val Val Lys Ala Glu Asp Tyr 
                85                  90                  95


Asp Glu Gly Glu Asn Gly Arg Val Thr Tyr Asp Met Thr Glu Gly Asp 
            100                 105                 110


Arg Gly Phe Phe Glu Ile Asp Gln Val Asn Gly Glu Val Arg Thr Thr 
        115                 120                 125


Arg Thr Phe Gly Glu Ser Ser Lys Ser Ser Tyr Glu Leu Ile Val Val 
    130                 135                 140


Ala His Asp His Gly Lys Thr Ser Leu Ser Ala Ser Ala Leu Val Leu 
145                 150                 155                 160


Ile Tyr Leu Ser Pro Ala Leu Asp Ala Gln Glu Ser Met Gly Ser Val 
                165                 170                 175


Asn Leu Ser Leu Ile Phe Ile Ile Ala Leu Gly Ser Ile Ala Gly Ile 
            180                 185                 190


Leu Phe Val Thr Met Ile Phe Val Ala Ile Lys Cys Lys Arg Asp Asn 
        195                 200                 205


Lys Glu Ile Arg Thr Tyr Asn Cys Arg Ile Ala Glu Tyr Ser Tyr Gly 
    210                 215                 220


His Gln Lys Lys Ser Ser Lys Lys Lys Lys Ile Ser Lys Asn Asp Ile 
225                 230                 235                 240


Arg Leu Val Pro Arg Asp Val Glu Glu Thr Asp Lys Met Asn Val Val 
                245                 250                 255


Ser Cys Ser Ser Leu Thr Ser Ser Leu Asn Tyr Phe Asp Tyr His Gln 
            260                 265                 270


Gln Thr Leu Pro Leu Gly Cys Arg Arg Ser Glu Ser Thr Phe Leu Asn 
        275                 280                 285


Val Glu Asn Gln Asn Thr Arg Asn Thr Ser Ala Asn His Ile Tyr His 
    290                 295                 300


His Ser Phe Asn Ser Gln Gly Pro Gln Gln Pro Asp Leu Ile Ile Asn 
305                 310                 315                 320


Gly Val Pro Leu Pro Glu Thr Glu Asn Tyr Ser Phe Asp Ser Asn Tyr 
                325                 330                 335


Val Asn Ser Arg Ala His Leu Ile Lys Ser Ser Ser Thr Phe Lys Asp 
            340                 345                 350


Leu Glu Gly Asn Ser Leu Lys Asp Ser Gly His Glu Glu Ser Asp Gln 
        355                 360                 365


Thr Asp Ser Glu His Asp Val Gln Arg Ser Leu Tyr Cys Asp Thr Ala 
    370                 375                 380


Val Asn Asp Val Leu Asn Thr Ser Val Thr Ser Met Gly Ser Gln Met 
385                 390                 395                 400


Pro Asp His Asp Gln Asn Glu Gly Phe His Cys Arg Glu Glu Cys Arg 
                405                 410                 415


Ile Leu Gly His Ser Asp Arg Cys Trp Met Pro Arg Asn Pro Met Pro 
            420                 425                 430


Ile Arg Ser Lys Ser Pro Glu His Val Arg Asn Ile Ile Ala Leu Ser 
        435                 440                 445


Ile Glu Ala Thr Ala Ala Asp Val Glu Ala Tyr Asp Asp Cys Gly Pro 
    450                 455                 460


Thr Lys Arg Thr Phe Ala Thr Phe Gly Lys Asp Val Ser Asp His Pro 
465                 470                 475                 480


Ala Glu Glu Arg Pro Thr Leu Lys Gly Lys Arg Thr Val Asp Val Thr 
                485                 490                 495


Ile Cys Ser Pro Lys Val Asn Ser Val Ile Arg Glu Ala Gly Asn Gly 
            500                 505                 510


Cys Glu Ala Ile Ser Pro Val Thr Ser Pro Leu His Leu Lys Ser Ser 
        515                 520                 525


Leu Pro Thr Lys Pro Ser Val Ser Tyr Thr Ile Ala Leu Ala Pro Pro 
    530                 535                 540


Ala Arg Asp Leu Glu Gln Tyr Val Asn Asn Val Asn Asn Gly Pro Thr 
545                 550                 555                 560


Arg Pro Ser Glu Ala Glu Pro Arg Gly Ala Asp Ser Glu Lys Val Met 
                565                 570                 575


His Glu Val Ser Pro Ile Leu Lys Glu Gly Arg Asn Lys Glu Ser Pro 
            580                 585                 590


Gly Val Lys Arg Leu Lys Asp Ile Val Leu 
        595                 600


<210>  10607
<211>  375
<212>  DNA
<213>  Homo sapiens

<400>  10607
gtcctaatct acttgtcccc tgctctcgat gcccaagagt caatgggctc tgtgaacttg     60

tccttgattt tcattattgc cctgggctcc attgcgggca tcctctttgt aactatgatc    120

ttcgtggcaa tcaagtgcaa gcgagacaac aaagagatcc ggacctacaa ctgcagtaat    180

tgtttaacca tcacttgtct cctcggctgt tttataaaag gacaaaacag caagtgtctg    240

cattgcatct cggtttctcc cattagcgag gagcaagaca aaaagacaga ggagaaagtg    300

agcctaaggg gaaagagaat tgctgagtac tcctatgggc atcaaaagaa atcaagcaag    360

aagaaaaaaa tcagt                                                     375


<210>  10608
<211>  110
<212>  PRT
<213>  Homo sapiens

<400>  10608

Met Gly Ser Val Asn Leu Ser Leu Ile Phe Ile Ile Ala Leu Gly Ser 
1               5                   10                  15


Ile Ala Gly Ile Leu Phe Val Thr Met Ile Phe Val Ala Ile Lys Cys 
            20                  25                  30


Lys Arg Asp Asn Lys Glu Ile Arg Thr Tyr Asn Cys Ser Asn Cys Leu 
        35                  40                  45


Thr Ile Thr Cys Leu Leu Gly Cys Phe Ile Lys Gly Gln Asn Ser Lys 
    50                  55                  60


Cys Leu His Cys Ile Ser Val Ser Pro Ile Ser Glu Glu Gln Asp Lys 
65                  70                  75                  80


Lys Thr Glu Glu Lys Val Ser Leu Arg Gly Lys Arg Ile Ala Glu Tyr 
                85                  90                  95


Ser Tyr Gly His Gln Lys Lys Ser Ser Lys Lys Lys Lys Ile 
            100                 105                 110


<210>  10609
<211>  3575
<212>  DNA
<213>  Homo sapiens

<400>  10609
aatagcagag aagggctagg gagcggttgc cgagcagggg ctctaccgcg ggcgggcagc     60

tgtgccagct aaccgtctgg gatctcgcac tgggggctgc agcttttccc cgcctcgagc    120

cagtgtgcgg gggcgggaga agagccaggg ggagcgggct gggcccgggg ctgcggctgc    180

ggccgcgggg ctgcggctcc ccagccccgc cagctggagc gctcggaggt agaggaaagg    240

tcttgacggg gtggctggat ccgtggcaga atccagttcc agattctaga cttgagggtt    300

ctgggctgtt ggtctgtaga agcgaaggag agaaggactc aaatccaggc caagtgtatg    360

gctgtctgag gtattggaac agaaggaggt ccattcctgt tggtgacaac accgtggccc    420

tgttctggga tgagcaaggt gtaaaggttt cccccaagaa agagcagctg agtccttgca    480

tcttgtggca gctggtgtgc ccagcactga gtctgtagga gctgaagcca gcccggaccc    540

ttctcatggg cagtgcccac ctgtgctgaa gtcctgcagc ggtggcggtg tgaggagctg    600

tgaaattagt tgtaactgaa aatgtctgac ggtctggata atgaagagaa acccccggct    660

cctccactga ggatgaatag taacaaccgg gattcttcag cactcaacca cagctccaaa    720

ccacttccca tggcccctga agagaagaat aagaaagcca ggcttcgctc tatcttccca    780

ggaggagggg ataaaaccaa taagaagaag gagaaagagc gcccagagat ctctcttcct    840

tcagactttg agcatacgat tcatgtgggg tttgatgcag tcaccgggga attcactgga    900

attccagagc aatgggcacg attactccaa acttccaaca taacaaaatt ggaacagaag    960

aagaacccac aagctgttct agatgttctc aaattctatg attccaaaga aacagtcaac   1020

aaccagaaat acatgagctt tacatcagga gataaaagtg cacatggata catagcagcc   1080

catccttcga gtacaaaaac agcatctgag cctccattgg cccctcctgt gtctgaagaa   1140

gaagatgaag aggaagaaga agaagaagat gaaaatgagc caccaccagt tatcgcacca   1200

agaccagagc atacaaaatc aatctatact cgttctgtgg ttgaatccat tgcttcacca   1260

gcagtaccaa ataaagaggt cacaccaccc tctgctgaaa atgccaattc cagtactttg   1320

tacaggaaca cagatcggca aagaaaaaaa tccaagatga cagatgagga gatcttagag   1380

aagctaagaa gcattgtgag tgttggggac ccaaagaaaa aatacacaag atttgaaaaa   1440

attggtcaag gggcatcagg tactgtttat acagcactag acattgcaac aggacaagag   1500

gtggccataa agcagatgaa ccttcaacag caacccaaga aggaattaat tattaatgaa   1560

attctggtca tgagggaaaa taagaaccct aatattgtta attatttaga tagctacttg   1620

gtgggtgatg aactatgggt agtcatggaa tacttggctg gtggctctct gactgatgtg   1680

gtcacagaga cctgtatgga tgaaggacag atagcagctg tctgcagaga gtgcctgcaa   1740

gctttggatt tcctgcactc aaaccaggtg atccatagag atataaagag tgacaatatt   1800

cttctcggga tggatggctc tgttaaattg actgactttg ggttctgtgc ccagatcact   1860

cctgagcaaa gtaaacgaag cactatggtg ggaaccccat attggatggc acctgaggtg   1920

gtgactcgaa aagcttatgg tccgaaagtt gatatctggt ctcttggaat tatggcaatt   1980

gaaatggtgg aaggtgaacc cccttacctt aatgaaaatc cactcagggc attgtatctg   2040

atagccacta atggaactcc agagctccag aatcctgaga gactgtcagc tgtattccgt   2100

gactttttaa atcgctgtct tgagatggat gtggataggc gaggatctgc caaggagctt   2160

ttgcagcatc catttttaaa attagccaag cctctctcca gcctgactcc tctgattatc   2220

gctgcaaagg aagcaattaa gaacagcagc cgctaagact gcaagcctta cacctcacca   2280

tctccctcat gagtaagact gaaataaaac tctgctgcag gaaagatgga agaaaagaca   2340

gtcaaatggg gtgggggttc tttacctttc aaatgaatag aaacttctta taagcctttt   2400

tcctactccc tcagattatg taatttattt gtaagcctga atcgcagccc aaacagggca   2460

gcaatgttga agtgaccata aagtggtcac ttccaccgtg aagcgaaaga gccagtagtg   2520

aatcccctca ttttgtgcat tcactttgaa gaaaaaggtt tctcaaagat gcacactccc   2580

tcttcatagt gttgtgtttg tttttaagtt agagagtagt ccctcttgca ttcaaacctc   2640

cttcaaaact ccttacccaa tgtgatgttt ttcacttgca ttgtcattag atgtccagaa   2700

aaaaaaaaga tgtcaaaatg tttttctaaa aaaagaaagc aaaaaaagca aggcaaaaaa   2760

aaaaaaaaaa acaaacaaaa acaaaaacaa aacaaaaaca agcaaacaaa aaataccaga   2820

gcaagtactg tgtgaacatg tggaagtcca tgccctaata gagttgcaat tttttattct   2880

tcttctatag tggtggcttg gtttgtgtac ctatttttct gcatttgtat tggaaaaggt   2940

ttcttttaag acattttcca aaagtggaga ggaatatgtg tgttcaggaa gggctttcaa   3000

aaaactgtat atctaaataa agctcaaacg gtgaaatcct gtcacatttt cacaatgatg   3060

cttaaaagat aattgagtaa accaggttgt taatctcctt aatacctgaa agaggacaca   3120

ctgaaactga aactgtgaca tcctgctagg tgagttcagg ttctgaacct aggaaatcct   3180

cataggagaa accacattta aacaaagatg ggactttctc tgagagccaa aaccagataa   3240

atgtagaata ctgaaatcct tgttggacat taagtaaaca aagataatga tacctaaatt   3300

aatcctctct tgtgcttatg aaacatatgc actgtaaaat aggcatacca ggaggaaata   3360

gatacattaa tcatcattta cttatgatac aaattattta ttttgacaat ttataacgtt   3420

taaaaaagtt ttttaaagat ctagagaaag gtgatatagt aaacattcaa ctctgtaaga   3480

aatgggaggt cagtgaaggc tacatcccaa tcaatatttg gctctaagta cctcttccca   3540

tttttcctat gtatcaccta tttctgtttc ggaat                              3575


<210>  10610
<211>  544
<212>  PRT
<213>  Homo sapiens

<400>  10610

Met Ser Asp Gly Leu Asp Asn Glu Glu Lys Pro Pro Ala Pro Pro Leu 
1               5                   10                  15


Arg Met Asn Ser Asn Asn Arg Asp Ser Ser Ala Leu Asn His Ser Ser 
            20                  25                  30


Lys Pro Leu Pro Met Ala Pro Glu Glu Lys Asn Lys Lys Ala Arg Leu 
        35                  40                  45


Arg Ser Ile Phe Pro Gly Gly Gly Asp Lys Thr Asn Lys Lys Lys Glu 
    50                  55                  60


Lys Glu Arg Pro Glu Ile Ser Leu Pro Ser Asp Phe Glu His Thr Ile 
65                  70                  75                  80


His Val Gly Phe Asp Ala Val Thr Gly Glu Phe Thr Gly Ile Pro Glu 
                85                  90                  95


Gln Trp Ala Arg Leu Leu Gln Thr Ser Asn Ile Thr Lys Leu Glu Gln 
            100                 105                 110


Lys Lys Asn Pro Gln Ala Val Leu Asp Val Leu Lys Phe Tyr Asp Ser 
        115                 120                 125


Lys Glu Thr Val Asn Asn Gln Lys Tyr Met Ser Phe Thr Ser Gly Asp 
    130                 135                 140


Lys Ser Ala His Gly Tyr Ile Ala Ala His Pro Ser Ser Thr Lys Thr 
145                 150                 155                 160


Ala Ser Glu Pro Pro Leu Ala Pro Pro Val Ser Glu Glu Glu Asp Glu 
                165                 170                 175


Glu Glu Glu Glu Glu Glu Asp Glu Asn Glu Pro Pro Pro Val Ile Ala 
            180                 185                 190


Pro Arg Pro Glu His Thr Lys Ser Ile Tyr Thr Arg Ser Val Val Glu 
        195                 200                 205


Ser Ile Ala Ser Pro Ala Val Pro Asn Lys Glu Val Thr Pro Pro Ser 
    210                 215                 220


Ala Glu Asn Ala Asn Ser Ser Thr Leu Tyr Arg Asn Thr Asp Arg Gln 
225                 230                 235                 240


Arg Lys Lys Ser Lys Met Thr Asp Glu Glu Ile Leu Glu Lys Leu Arg 
                245                 250                 255


Ser Ile Val Ser Val Gly Asp Pro Lys Lys Lys Tyr Thr Arg Phe Glu 
            260                 265                 270


Lys Ile Gly Gln Gly Ala Ser Gly Thr Val Tyr Thr Ala Leu Asp Ile 
        275                 280                 285


Ala Thr Gly Gln Glu Val Ala Ile Lys Gln Met Asn Leu Gln Gln Gln 
    290                 295                 300


Pro Lys Lys Glu Leu Ile Ile Asn Glu Ile Leu Val Met Arg Glu Asn 
305                 310                 315                 320


Lys Asn Pro Asn Ile Val Asn Tyr Leu Asp Ser Tyr Leu Val Gly Asp 
                325                 330                 335


Glu Leu Trp Val Val Met Glu Tyr Leu Ala Gly Gly Ser Leu Thr Asp 
            340                 345                 350


Val Val Thr Glu Thr Cys Met Asp Glu Gly Gln Ile Ala Ala Val Cys 
        355                 360                 365


Arg Glu Cys Leu Gln Ala Leu Asp Phe Leu His Ser Asn Gln Val Ile 
    370                 375                 380


His Arg Asp Ile Lys Ser Asp Asn Ile Leu Leu Gly Met Asp Gly Ser 
385                 390                 395                 400


Val Lys Leu Thr Asp Phe Gly Phe Cys Ala Gln Ile Thr Pro Glu Gln 
                405                 410                 415


Ser Lys Arg Ser Thr Met Val Gly Thr Pro Tyr Trp Met Ala Pro Glu 
            420                 425                 430


Val Val Thr Arg Lys Ala Tyr Gly Pro Lys Val Asp Ile Trp Ser Leu 
        435                 440                 445


Gly Ile Met Ala Ile Glu Met Val Glu Gly Glu Pro Pro Tyr Leu Asn 
    450                 455                 460


Glu Asn Pro Leu Arg Ala Leu Tyr Leu Ile Ala Thr Asn Gly Thr Pro 
465                 470                 475                 480


Glu Leu Gln Asn Pro Glu Arg Leu Ser Ala Val Phe Arg Asp Phe Leu 
                485                 490                 495


Asn Arg Cys Leu Glu Met Asp Val Asp Arg Arg Gly Ser Ala Lys Glu 
            500                 505                 510


Leu Leu Gln His Pro Phe Leu Lys Leu Ala Lys Pro Leu Ser Ser Leu 
        515                 520                 525


Thr Pro Leu Ile Ile Ala Ala Lys Glu Ala Ile Lys Asn Ser Ser Arg 
    530                 535                 540


<210>  10611
<211>  1878
<212>  DNA
<213>  Homo sapiens

<400>  10611
ggctcgtggc tacccgaaag tagttactca gatcactgtt cacagtgctg aggacctgga     60

gaagaagtat gccaatgaaa ctgtaaaccc atatttggtc atcaaatgtg gaaaggagga    120

agtccgttct cctgtccaga agaatacagt tcatgccatt tttgacaccc aggccatttt    180

ctacagaagg accactgaca ttcctattat agtacaggtc tggaacagcc gaaaattctg    240

tgatcagttc ttggggcagg ttactctgga tgctgacccc agcgactgcc gtgatctgaa    300

gtctctgtac ctgcgtaaga agggtggtcc aactgccaaa gtcaagcaag gccacatcag    360

cttcaaggtt atttccagcg atgatctcac tgagctctaa atctgcaatc ccagagaatc    420

ctgacaaagc gtgccaccct tttattttcc gtcaggtgcc aggtcttagt taagattcac    480

aatctttaga aagaatgaga ttcacaataa ttaactcttc ctctcttctg ataaattccc    540

catacctccc aatccaagta gcatctgtag ctacataacc tatatacctc cagcagctgg    600

acatggggag gcgacagtcc tatctagaca tcatacacat ttgccaagaa aggatctctg    660

gggcttccgg gggtgagatt caagtaggac aataacaaga ggctggacac cctacagatg    720

tctttgatgt tttcagttgt ttgatatatc tcccctgtag ggcatgttga ggaaggagga    780

gggctgatca aggccaagct ggtctagcct gacatcctag ctcctgactg aacactatag    840

acttcccagc agcatttcac ccagcagcca gagccggctt taagtcccca acccttacag    900

acaccactgc caccaccacc aaccacgacc accaccacca ccaccactca ccaccatcat    960

cacctccgga aagtgtagtc ctgccctaac ccaagtcacc cccgacagta aattttacct   1020

tcatgttgag aaagcttcct ggtgcttaat caagagctgg agttcaatga gtcctagaca   1080

gtgagagggg cctgagcttc agctcaatgg aagcctgctg tgtgccacaa gacggaaaag   1140

tggaagaagc tgcagtggga gacaaagcct cggtccccca cccatccaca cacacctaca   1200

ctcacacacg cgcacatggg cgcgcacgaa ctaccattca ggcagtcagt gggcaagagg   1260

aaagataagt aagtaccata cacacctaaa agatgagaga attcatccag acatattaca   1320

gccagtttgg ggcccctgac tgcaatgtga aacctctcgc tgctgctagg tttacaaaca   1380

agcccattgt cctgtgcctc ctaatatcat ttgtactgaa gaccccatct ggggacttga   1440

gactttggtc ccagcccaga ctcctcagac ttttctctca gttgggatgc ttcactcgct   1500

gggggtgttt gtttgccctc tcatttttca gtacttctac agaattttct ctagagtcag   1560

tcattatgaa atgtacttcc ctccatctta acctatcaac tttctgcccc tccttcaagg   1620

cccagtataa atgccacctc ctccatgaag ccttccctaa ttccacccca aacccccacc   1680

ttcaacaata tttcaacgct tctgcaatga tgaaaaagaa acatagttgt agtacttagc   1740

ctacctagac cagcaagcat tcatttttag ctcgctcatt ttttaccatg ttttccagtc   1800

tgtttaactt ctgcagtgcc ttcactacac tgccttacat aaaccaaatc acaataaagt   1860

tcatattcag tacattga                                                 1878


<210>  10612
<211>  148
<212>  PRT
<213>  Homo sapiens

<400>  10612

Met Arg Glu Phe Ile Gln Thr Tyr Tyr Ser Gln Phe Gly Ala Pro Asp 
1               5                   10                  15


Cys Asn Val Lys Pro Leu Ala Ala Ala Arg Phe Thr Asn Lys Pro Ile 
            20                  25                  30


Val Leu Cys Leu Leu Ile Ser Phe Val Leu Lys Thr Pro Ser Gly Asp 
        35                  40                  45


Leu Arg Leu Trp Ser Gln Pro Arg Leu Leu Arg Leu Phe Ser Gln Leu 
    50                  55                  60


Gly Cys Phe Thr Arg Trp Gly Cys Leu Phe Ala Leu Ser Phe Phe Ser 
65                  70                  75                  80


Thr Ser Thr Glu Phe Ser Leu Glu Ser Val Ile Met Lys Cys Thr Ser 
                85                  90                  95


Leu His Leu Asn Leu Ser Thr Phe Cys Pro Ser Phe Lys Ala Gln Tyr 
            100                 105                 110


Lys Cys His Leu Leu His Glu Ala Phe Pro Asn Ser Thr Pro Asn Pro 
        115                 120                 125


His Leu Gln Gln Tyr Phe Asn Ala Ser Ala Met Met Lys Lys Lys His 
    130                 135                 140


Ser Cys Ser Thr 
145


<210>  10613
<211>  3713
<212>  DNA
<213>  Homo sapiens

<400>  10613
atcccgtctg cacatctggt agaggcactt tccacatttt cctcatgact caggatcagt     60

ttctgactgc tgggcggggc aaagcctcct gaagttgctg cgaggcacct ccccctgtga    120

gcagagcttg gtacagccca aatagttttc aggttaagaa agccagaatc tttgttcagc    180

cacactgact gaacagactt ttagtggggt tacctggcta acagcagcag cggcaacggc    240

agcagcagca gcagcagcag cagcagcagc agcagggctc ctgggataac tcaggcatag    300

ttcaacacta tgggtcctcc tctgaagctc ttcaaaaacc agaaatacca ggaactgaag    360

caggaatgca tcaaagacag cagacttttc tgtgatccaa catttctgcc tgagaatgat    420

tctcttttct acaaccgact gcttcctgga aaggtggtgt ggaaacgtcc ccaggacatc    480

tgtgatgacc cccatctgat tgtgggcaac attagcaacc accagctgac ccaagggaga    540

ctggggcaca agccaatggt ttctgcattt tcctgtttgg ctgttcagga gtctcattgg    600

acaaagacaa ttcccaacca taaggaacag gaatgggacc ctcaaaaaac agaaaaatac    660

gctgggatat ttcactttcg tttctggcat tttggagaat ggactgaagt ggtgattgat    720

gacttgttgc ccaccattaa cggagatctg gtcttctctt tctccacttc catgaatgag    780

ttttggaatg ctctgctgga aaaagcttat gcaaagctgc taggctgtta tgaggccctg    840

gatggtttga ccatcactga tattattgtg gacttcacgg gcacattggc tgaaactgtt    900

gacatgcaga aaggaagata cactgagctt gttgaggaga agtacaagct attcggagaa    960

ctgtacaaaa catttaccaa aggtggtctg atctgctgtt ccattgagtc tcccaatcag   1020

gaggagcaag aagttgaaac tgattggggt ctgctgaagg gccataccta taccatgact   1080

gatattcgca aaattcgtct tggagagaga cttgtggaag tcttcagtgc tgagaaggtg   1140

tatatggttc gcctgagaaa ccccttggga agacaggaat ggagtggccc ctggagtgaa   1200

atttctgaag agtggcagca actgactgca tcagatcgca agaacctggg gcttgttatg   1260

tctgatgatg gagagttttg gatgagcttg gaggactttt gccgcaactt tcacaaactg   1320

aatgtctgcc gcaatgtgaa caaccctatt tttggccgaa aggagctgga atcggtgttg   1380

ggatgctgga ctgtggatga tgatcccctg atgaaccgct caggaggctg ctataacaac   1440

cgtgatacct tcctgcagaa tccccagtac atcttcactg tgcctgagga tgggcacaag   1500

gtcattatgt cactgcagca gaaggacctg cgcacttacc gccgaatggg aagacctgac   1560

aattacatca ttggctttga gctcttcaag gtggagatga accgcaaatt ccgcctccac   1620

cacctctaca tccaggagcg tgctgggact tccacctata ttgacacccg cacagtgttt   1680

ctgagcaagt acctgaagaa gggcaactat gtgcttgtcc caaccatgtt ccagcatggt   1740

cgcaccagcg agtttctcct gagaatcttc tctgaagtgc ctgtccagct cagggaactg   1800

actctggaca tgcccaaaat gtcctgctgg aacctggctc gtggctaccc gaaagtagtt   1860

actcagatca ctgttcacag tgctgaggac ctggagaaga agtatgccaa tgaaactgta   1920

aacccatatt tggtcatcaa atgtggaaag gaggaagtcc gttctcctgt ccagaagaat   1980

acagttcatg ccatttttga cacccaggcc attttctaca gaaggaccac tgacattcct   2040

attatagtac aggtctggaa cagccgaaaa ttctgtgatc agttcttggg gcaggttact   2100

ctggatgctg accccagcga ctgccgtgat ctgaagtctc tgtacctgcg taagaagggt   2160

ggtccaactg ccaaagtcaa gcaaggccac atcagcttca aggttatttc cagcgatgat   2220

ctcactgagc tctaaatctg caatcccaga gaatcctgac aaagcgtgcc acccttttat   2280

tttccgtcag gtgccaggtc ttagttaaga ttcacaatct ttagaaagaa tgagattcac   2340

aataattaac tcttcctctc ttctgataaa ttccccatac ctcccaatcc aagtagcatc   2400

tgtagctaca taacctatat acctccagca gctggacatg gggaggcgac agtcctatct   2460

agacatcata cacatttgcc aagaaaggat ctctggggct tccgggggtg agattcaagt   2520

aggacaataa caagaggctg gacaccctac agatgtcttt gatgttttca gttgtttgat   2580

atatctcccc tgtagggcat gttgaggaag gaggagggct gatcaaggcc aagctggtct   2640

agcctgacat cctagctcct gactgaacac tatagacttc ccagcagcat ttcacccagc   2700

agccagagcc ggctttaagt ccccaaccct tacagacacc actgccacca ccaccaacca   2760

cgaccaccac caccaccacc actcaccacc atcatcacct ccggaaagtg tagtcctgcc   2820

ctaacccaag tcacccccga cagtaaattt taccttcatg ttgagaaagc ttcctggtgc   2880

ttaatcaaga gctggagttc aatgagtcct agacagtgag aggggcctga gcttcagctc   2940

aatggaagcc tgctgtgtgc cacaagacgg aaaagtggaa gaagctgcag tgggagacaa   3000

agcctcggtc ccccacccat ccacacacac ctacactcac acacgcgcac atgggcgcgc   3060

acgaactacc attcaggcag tcagtgggca agaggaaaga taagtaagta ccatacacac   3120

ctaaaagatg agagaattca tccagacata ttacagccag tttggggccc ctgactgcaa   3180

tgtgaaacct ctcgctgctg ctaggtttac aaacaagccc attgtcctgt gcctcctaat   3240

atcatttgta ctgaagaccc catctgggga cttgagactt tggtcccagc ccagactcct   3300

cagacttttc tctcagttgg gatgcttcac tcgctggggg tgtttgtttg ccctctcatt   3360

tttcagtact tctacagaat tttctctaga gtcagtcatt atgaaatgta cttccctcca   3420

tcttaaccta tcaactttct gcccctcctt caaggcccag tataaatgcc acctcctcca   3480

tgaagccttc cctaattcca ccccaaaccc ccaccttcaa caatatttca acgcttctgc   3540

aatgatgaaa aagaaacata gttgtagtac ttagcctacc tagaccagca agcattcatt   3600

tttagctcgc tcatttttta ccatgttttc cagtctgttt aacttctgca gtgccttcac   3660

tacactgcct tacataaacc aaatcacaat aaagttcata ttcagtacat tga          3713


<210>  10614
<211>  641
<212>  PRT
<213>  Homo sapiens

<400>  10614

Met Gly Pro Pro Leu Lys Leu Phe Lys Asn Gln Lys Tyr Gln Glu Leu 
1               5                   10                  15


Lys Gln Glu Cys Ile Lys Asp Ser Arg Leu Phe Cys Asp Pro Thr Phe 
            20                  25                  30


Leu Pro Glu Asn Asp Ser Leu Phe Tyr Asn Arg Leu Leu Pro Gly Lys 
        35                  40                  45


Val Val Trp Lys Arg Pro Gln Asp Ile Cys Asp Asp Pro His Leu Ile 
    50                  55                  60


Val Gly Asn Ile Ser Asn His Gln Leu Thr Gln Gly Arg Leu Gly His 
65                  70                  75                  80


Lys Pro Met Val Ser Ala Phe Ser Cys Leu Ala Val Gln Glu Ser His 
                85                  90                  95


Trp Thr Lys Thr Ile Pro Asn His Lys Glu Gln Glu Trp Asp Pro Gln 
            100                 105                 110


Lys Thr Glu Lys Tyr Ala Gly Ile Phe His Phe Arg Phe Trp His Phe 
        115                 120                 125


Gly Glu Trp Thr Glu Val Val Ile Asp Asp Leu Leu Pro Thr Ile Asn 
    130                 135                 140


Gly Asp Leu Val Phe Ser Phe Ser Thr Ser Met Asn Glu Phe Trp Asn 
145                 150                 155                 160


Ala Leu Leu Glu Lys Ala Tyr Ala Lys Leu Leu Gly Cys Tyr Glu Ala 
                165                 170                 175


Leu Asp Gly Leu Thr Ile Thr Asp Ile Ile Val Asp Phe Thr Gly Thr 
            180                 185                 190


Leu Ala Glu Thr Val Asp Met Gln Lys Gly Arg Tyr Thr Glu Leu Val 
        195                 200                 205


Glu Glu Lys Tyr Lys Leu Phe Gly Glu Leu Tyr Lys Thr Phe Thr Lys 
    210                 215                 220


Gly Gly Leu Ile Cys Cys Ser Ile Glu Ser Pro Asn Gln Glu Glu Gln 
225                 230                 235                 240


Glu Val Glu Thr Asp Trp Gly Leu Leu Lys Gly His Thr Tyr Thr Met 
                245                 250                 255


Thr Asp Ile Arg Lys Ile Arg Leu Gly Glu Arg Leu Val Glu Val Phe 
            260                 265                 270


Ser Ala Glu Lys Val Tyr Met Val Arg Leu Arg Asn Pro Leu Gly Arg 
        275                 280                 285


Gln Glu Trp Ser Gly Pro Trp Ser Glu Ile Ser Glu Glu Trp Gln Gln 
    290                 295                 300


Leu Thr Ala Ser Asp Arg Lys Asn Leu Gly Leu Val Met Ser Asp Asp 
305                 310                 315                 320


Gly Glu Phe Trp Met Ser Leu Glu Asp Phe Cys Arg Asn Phe His Lys 
                325                 330                 335


Leu Asn Val Cys Arg Asn Val Asn Asn Pro Ile Phe Gly Arg Lys Glu 
            340                 345                 350


Leu Glu Ser Val Leu Gly Cys Trp Thr Val Asp Asp Asp Pro Leu Met 
        355                 360                 365


Asn Arg Ser Gly Gly Cys Tyr Asn Asn Arg Asp Thr Phe Leu Gln Asn 
    370                 375                 380


Pro Gln Tyr Ile Phe Thr Val Pro Glu Asp Gly His Lys Val Ile Met 
385                 390                 395                 400


Ser Leu Gln Gln Lys Asp Leu Arg Thr Tyr Arg Arg Met Gly Arg Pro 
                405                 410                 415


Asp Asn Tyr Ile Ile Gly Phe Glu Leu Phe Lys Val Glu Met Asn Arg 
            420                 425                 430


Lys Phe Arg Leu His His Leu Tyr Ile Gln Glu Arg Ala Gly Thr Ser 
        435                 440                 445


Thr Tyr Ile Asp Thr Arg Thr Val Phe Leu Ser Lys Tyr Leu Lys Lys 
    450                 455                 460


Gly Asn Tyr Val Leu Val Pro Thr Met Phe Gln His Gly Arg Thr Ser 
465                 470                 475                 480


Glu Phe Leu Leu Arg Ile Phe Ser Glu Val Pro Val Gln Leu Arg Glu 
                485                 490                 495


Leu Thr Leu Asp Met Pro Lys Met Ser Cys Trp Asn Leu Ala Arg Gly 
            500                 505                 510


Tyr Pro Lys Val Val Thr Gln Ile Thr Val His Ser Ala Glu Asp Leu 
        515                 520                 525


Glu Lys Lys Tyr Ala Asn Glu Thr Val Asn Pro Tyr Leu Val Ile Lys 
    530                 535                 540


Cys Gly Lys Glu Glu Val Arg Ser Pro Val Gln Lys Asn Thr Val His 
545                 550                 555                 560


Ala Ile Phe Asp Thr Gln Ala Ile Phe Tyr Arg Arg Thr Thr Asp Ile 
                565                 570                 575


Pro Ile Ile Val Gln Val Trp Asn Ser Arg Lys Phe Cys Asp Gln Phe 
            580                 585                 590


Leu Gly Gln Val Thr Leu Asp Ala Asp Pro Ser Asp Cys Arg Asp Leu 
        595                 600                 605


Lys Ser Leu Tyr Leu Arg Lys Lys Gly Gly Pro Thr Ala Lys Val Lys 
    610                 615                 620


Gln Gly His Ile Ser Phe Lys Val Ile Ser Ser Asp Asp Leu Thr Glu 
625                 630                 635                 640


Leu 



<210>  10615
<211>  3582
<212>  DNA
<213>  Homo sapiens

<400>  10615
atcccgtctg cacatctggt agaggcactt tccacatttt cctcatgact caggatcagt     60

ttctgactgc tgggcggggc aaagcctcct gaagttgctg cgaggcacct ccccctgtga    120

gcagagcttg gtacagccca aatagttttc aggttaagaa agccagaatc tttgttcagc    180

cacactgact gaacagactt ttagtggggt tacctggcta acagcagcag cggcaacggc    240

agcagcagca gcagcagcag cagcagcagc agcagggctc ctgggataac tcaggcatag    300

ttcaacacta tgggtcctcc tctgaagctc ttcaaaaacc agaaatacca ggaactgaag    360

caggaatgca tcaaagacag cagacttttc tgtgatccaa catttctgcc tgagaatgat    420

tctcttttct acaaccgact gcttcctgga aaggtggtgt ggaaacgtcc ccaggacatc    480

tgtgatgacc cccatctgat tgtgggcaac attagcaacc accagctgac ccaagggaga    540

ctggggcaca agccaatggt ttctgcattt tcctgtttgg ctgttcagga gtctcattgg    600

acaaagacaa ttcccaacca taaggaacag gaatgggacc ctcaaaaaac agaaaaatac    660

gctgggatat ttcactttcg tttctggcat tttggagaat ggactgaagt ggtgattgat    720

gacttgttgc ccaccattaa cggagatctg gtcttctctt tctccacttc catgaatgag    780

ttttggaatg ctctgctgga aaaagcttat gcaaagctgc taggctgtta tgaggccctg    840

gatggtttga ccatcactga tattattgtg gacttcacgg gcacattggc tgaaactgtt    900

gacatgcaga aaggaagata cactgagctt gttgaggaga agtacaagct attcggagaa    960

ctgtacaaaa catttaccaa aggtggtctg atctgctgtt ccattgagtc tcccaatcag   1020

gaggagcaag aagttgaaac tgattggggt ctgctgaagg gccataccta taccatgact   1080

gatattcgca aaattcgtct tggagagaga cttgtggaag tcttcagtgc tgagaaggtg   1140

tatatggttc gcctgagaaa ccccttggga agacaggaat ggagtggccc ctggagtgaa   1200

atttctgaag agtggcagca actgactgca tcagatcgca agaacctggg gcttgttatg   1260

tctgatgatg gagagttttg gatgagcttg gaggactttt gccgcaactt tcacaaactg   1320

aatgtctgcc gcaatgtgaa caaccctatt tttggccgaa aggagctgga atcggtgttg   1380

ggatgctgga ctgtggatga tgatcccctg atgaaccgct caggaggctg ctataacaac   1440

cgtgatacct tcctgcagaa tccccagtac atcttcactg tgcctgagga tgggcacaag   1500

gtcattatgt cactgcagca gaaggacctg cgcacttacc gccgaatggg aagacctgac   1560

aattacatca ttggctttga gctcttcaag gtggagatga accgcaaatt ccgcctccac   1620

cacctctaca tccaggagcg tgctgggact tccacctata ttgacacccg cacagtgttt   1680

ctgagcaagt acctgaagaa gggcaactat gtgcttgtcc caaccatgtt ccagcatggt   1740

cgcaccagcg agtttctcct gagaatcttc tctgaagtgc ctgtccagct cagggaactg   1800

actctggaca tgcccaaaat gtcctgctgg aacctggctc gtggctaccc gaaagtagtt   1860

actcagatca ctgttcacag tgctgaggac ctggagaaga agtatgccaa tgaaactgta   1920

aacccatatt tggtcatcaa atgtggaaag gaggaagtcc gttctcctgt ccagaagaat   1980

acagttcatg ccatttttga cacccaggcc attttctaca gaaggaccac tgacattcct   2040

attatagtac aggtctggaa cagccgaaaa ttctgtgatc agttcttggg gcaggttact   2100

ctggatgctg accccagcga ctgccgtgat ctgaagtctc tgtacctgcg taagaagggt   2160

ggtccaactg ccaaagtcaa gcaaggccac atcagcttca aggttatttc cagcgatgat   2220

ctcactgagc tctaaatctg caatcccaga gaatcctgac aaagcgtgcc acccttttat   2280

tttccgtcag gtgccaggtc ttagttaaga ttcacaatct ttagaaagaa tgagattcac   2340

aataattaac tcttcctctc ttctgataaa ttccccatac ctcccaatcc aagtagcatc   2400

tgtagctaca taacctatat acctccagca gctggacatg gggaggcgac agtcctatct   2460

agacatcata cacatttgcc aagaaaggat ctctggggct tccgggggtg agattcaagt   2520

aggacaataa caagaggctg gacaccctac agatgtcttt gatgttttca gttgtttgat   2580

atatctcccc tgtagggcat gttgaggaag gaggagggct gatcaaggcc aagctggtct   2640

agcctgacat cctagctcct gactgaacac tatagacttc ccagcagcat ttcacccagc   2700

agccagagcc ggctttaagt ccccaaccct tacagacacc actgccacca ccaccaacca   2760

cgaccaccac caccaccacc actcaccacc atcatcacct ccggaaagtg tagtcctgcc   2820

ctaacccaag tcacccccga cagtaaattt taccttcatg ttgagaaagc ttcctggtgc   2880

ttaatcaaga gctggagttc aatgagtcct agacagtgag aggggcctga gcttcagctc   2940

aatggaagcc tgctgtgtgc cacaagacgg aaaagtggaa gaagctgcag tgggagacaa   3000

agcctcggtc ccccacccat ccacacacac ctacactcac acacgcgcac atgggcgcgc   3060

acgaactacc attcaggcag tcagtgggca agaggaaaga taagtaagta ccatacacac   3120

ctaaaagatg agagaattca tccagacata ttacagccag tttggggccc ctgactgcaa   3180

tgtgaaacct ctcgctgctg ctaggtttac aaacaagccc attgtcctgt gcctcctaat   3240

atcatttgta ctgaagaccc catctgggga cttgagactt tggtcccagc ccagactcct   3300

cagacttttc tctcagttgg gatgcttcac tcgctggggg tgtttgtttg ccctctcatt   3360

tttcagtact tctacagaat cccaccttca acaatatttc aacgcttctg caatgatgaa   3420

aaagaaacat agttgtagta cttagcctac ctagaccagc aagcattcat ttttagctcg   3480

ctcatttttt accatgtttt ccagtctgtt taacttctgc agtgccttca ctacactgcc   3540

ttacataaac caaatcacaa taaagttcat attcagtaca tt                      3582


<210>  10616
<211>  641
<212>  PRT
<213>  Homo sapiens

<400>  10616

Met Gly Pro Pro Leu Lys Leu Phe Lys Asn Gln Lys Tyr Gln Glu Leu 
1               5                   10                  15


Lys Gln Glu Cys Ile Lys Asp Ser Arg Leu Phe Cys Asp Pro Thr Phe 
            20                  25                  30


Leu Pro Glu Asn Asp Ser Leu Phe Tyr Asn Arg Leu Leu Pro Gly Lys 
        35                  40                  45


Val Val Trp Lys Arg Pro Gln Asp Ile Cys Asp Asp Pro His Leu Ile 
    50                  55                  60


Val Gly Asn Ile Ser Asn His Gln Leu Thr Gln Gly Arg Leu Gly His 
65                  70                  75                  80


Lys Pro Met Val Ser Ala Phe Ser Cys Leu Ala Val Gln Glu Ser His 
                85                  90                  95


Trp Thr Lys Thr Ile Pro Asn His Lys Glu Gln Glu Trp Asp Pro Gln 
            100                 105                 110


Lys Thr Glu Lys Tyr Ala Gly Ile Phe His Phe Arg Phe Trp His Phe 
        115                 120                 125


Gly Glu Trp Thr Glu Val Val Ile Asp Asp Leu Leu Pro Thr Ile Asn 
    130                 135                 140


Gly Asp Leu Val Phe Ser Phe Ser Thr Ser Met Asn Glu Phe Trp Asn 
145                 150                 155                 160


Ala Leu Leu Glu Lys Ala Tyr Ala Lys Leu Leu Gly Cys Tyr Glu Ala 
                165                 170                 175


Leu Asp Gly Leu Thr Ile Thr Asp Ile Ile Val Asp Phe Thr Gly Thr 
            180                 185                 190


Leu Ala Glu Thr Val Asp Met Gln Lys Gly Arg Tyr Thr Glu Leu Val 
        195                 200                 205


Glu Glu Lys Tyr Lys Leu Phe Gly Glu Leu Tyr Lys Thr Phe Thr Lys 
    210                 215                 220


Gly Gly Leu Ile Cys Cys Ser Ile Glu Ser Pro Asn Gln Glu Glu Gln 
225                 230                 235                 240


Glu Val Glu Thr Asp Trp Gly Leu Leu Lys Gly His Thr Tyr Thr Met 
                245                 250                 255


Thr Asp Ile Arg Lys Ile Arg Leu Gly Glu Arg Leu Val Glu Val Phe 
            260                 265                 270


Ser Ala Glu Lys Val Tyr Met Val Arg Leu Arg Asn Pro Leu Gly Arg 
        275                 280                 285


Gln Glu Trp Ser Gly Pro Trp Ser Glu Ile Ser Glu Glu Trp Gln Gln 
    290                 295                 300


Leu Thr Ala Ser Asp Arg Lys Asn Leu Gly Leu Val Met Ser Asp Asp 
305                 310                 315                 320


Gly Glu Phe Trp Met Ser Leu Glu Asp Phe Cys Arg Asn Phe His Lys 
                325                 330                 335


Leu Asn Val Cys Arg Asn Val Asn Asn Pro Ile Phe Gly Arg Lys Glu 
            340                 345                 350


Leu Glu Ser Val Leu Gly Cys Trp Thr Val Asp Asp Asp Pro Leu Met 
        355                 360                 365


Asn Arg Ser Gly Gly Cys Tyr Asn Asn Arg Asp Thr Phe Leu Gln Asn 
    370                 375                 380


Pro Gln Tyr Ile Phe Thr Val Pro Glu Asp Gly His Lys Val Ile Met 
385                 390                 395                 400


Ser Leu Gln Gln Lys Asp Leu Arg Thr Tyr Arg Arg Met Gly Arg Pro 
                405                 410                 415


Asp Asn Tyr Ile Ile Gly Phe Glu Leu Phe Lys Val Glu Met Asn Arg 
            420                 425                 430


Lys Phe Arg Leu His His Leu Tyr Ile Gln Glu Arg Ala Gly Thr Ser 
        435                 440                 445


Thr Tyr Ile Asp Thr Arg Thr Val Phe Leu Ser Lys Tyr Leu Lys Lys 
    450                 455                 460


Gly Asn Tyr Val Leu Val Pro Thr Met Phe Gln His Gly Arg Thr Ser 
465                 470                 475                 480


Glu Phe Leu Leu Arg Ile Phe Ser Glu Val Pro Val Gln Leu Arg Glu 
                485                 490                 495


Leu Thr Leu Asp Met Pro Lys Met Ser Cys Trp Asn Leu Ala Arg Gly 
            500                 505                 510


Tyr Pro Lys Val Val Thr Gln Ile Thr Val His Ser Ala Glu Asp Leu 
        515                 520                 525


Glu Lys Lys Tyr Ala Asn Glu Thr Val Asn Pro Tyr Leu Val Ile Lys 
    530                 535                 540


Cys Gly Lys Glu Glu Val Arg Ser Pro Val Gln Lys Asn Thr Val His 
545                 550                 555                 560


Ala Ile Phe Asp Thr Gln Ala Ile Phe Tyr Arg Arg Thr Thr Asp Ile 
                565                 570                 575


Pro Ile Ile Val Gln Val Trp Asn Ser Arg Lys Phe Cys Asp Gln Phe 
            580                 585                 590


Leu Gly Gln Val Thr Leu Asp Ala Asp Pro Ser Asp Cys Arg Asp Leu 
        595                 600                 605


Lys Ser Leu Tyr Leu Arg Lys Lys Gly Gly Pro Thr Ala Lys Val Lys 
    610                 615                 620


Gln Gly His Ile Ser Phe Lys Val Ile Ser Ser Asp Asp Leu Thr Glu 
625                 630                 635                 640


Leu 



<210>  10617
<211>  9406
<212>  DNA
<213>  Homo sapiens

<400>  10617
cttatttctt atgaatgtcg gatagctgca ccagcttggt ggggaaaggg tttgatgaat     60

agcacaaaga cactggctgt tccctggagg ctgtcccttt aaaggagaat cttagtttat    120

tctgggggga ggggatgcac acattagagt aggaaagagg gcttggaata aaatgaaaac    180

actccccctt catagtcatt gtactgaaat gcaaagactg cttcctaagc tggagatgct    240

aaccttgggt agctccttct gttctcttca aggggaattt tgtcaggcta tggattcatt    300

tacaactgtt agtcatgtgg gcatgtgtga ggaaacagat gccagtttta atgtatttag    360

cccgaagttc caatttgata ggagccactg tcagtctctg aggttccacc aaaatatgga    420

acttgatttt ggacactttg acgaaagaga taagacatcc aggaacatgc gaggctcccg    480

gatgaatggg ttgcctagcc ccactcacag cgcccactgt agcttctacc gaaccagaac    540

cttgcaggca ctgagtaatg agaagaaagc caagaaggta cgtttctacc gcaatgggga    600

ccgctacttc aaggggattg tgtacgctgt gtcctctgac cgttttcgca gctttgacgc    660

cttgctggct gacctgacgc gatctctgtc tgacaacatc aacctgcctc agggagtgcg    720

ttacatttac accattgatg gatccaggaa gatcggaagc atggatgaac tggaggaagg    780

ggaaagctat gtctgttcct cagacaactt ctttaaaaag gtggagtaca ccaagaatgt    840

caatcccaac tggtctgtca acgtaaaaac atctgccaat atgaaagccc cccagtcctt    900

ggctagcagc aacagtgcac aggccaggga gaacaaggac tttgtgcgcc ccaagctggt    960

taccatcatc cgcagtgggg tgaagcctcg gaaggctgtg cgtgtgcttc tgaacaagaa   1020

gacagcccac tcttttgagc aagtcctcac tgatatcaca gaagccatca aactggagac   1080

cggggttgtc aaaaaactct acactctgga tggaaaacag gtaacttgtc tccatgattt   1140

ctttggtgat gatgatgtgt ttattgcctg tggtcctgaa aaatttcgct atgctcagga   1200

tgatttttct ctggatgaaa atgaatgccg agtcatgaag ggaaacccat cagccacagc   1260

tggcccaaag gcatccccaa cacctcagaa gacttcagcc aagagccctg gtcctatgcg   1320

ccgaagcaag tctccagctg actcagcaaa cggaacctcc agcagccagc tctctacccc   1380

caagtctaag cagtctccca tctctacgcc caccagtcct ggcagcctcc ggaagcacaa   1440

ggacctgtac ctgcctctgt ccttggatga ctcggactcg cttggtgatt ccatgtaaag   1500

gaggggagag tgctcagagt ccagagtaca aatccaagcc tatcattgta gtagggtact   1560

tctgctcaag tgtccaacag ggctattggt gctttcaagt ttttattttg ttgttgttgt   1620

tattttgaaa aacacattgt aatatgttgg gtttattttc ctgtgatttc tcctctgggc   1680

cactgatcca cagttaccaa ttatgagaga tagattgata accatccttt ggggcagcat   1740

tccagggatg caaaatgtgc tagtccatga cctttcaatg gaaagcttag gtgcctgcgt   1800

tatatttgcc ctgtctaatt ttgcccatac agtcttcctt ctgtagaggg ctgtttacat   1860

atacagcact taaaatgttt gtgtgggaaa aaaaaaactc attggcagat ccaagaatga   1920

caaacacaag tgcccctttt ctctggatct caagaatggt ggaggaccct ggaaggacag   1980

caaggcagct ccccagcctc actcttcact cctgattgag gcccgggttt gttgtccagc   2040

accaattctg gctgtcaatg gggagaaata aaccaacaac ttataattgt gacaccagat   2100

gcttaggatc ctggtgctgg gttagctaag agaatagaca gaattggaaa atactgcaga   2160

catttccgaa gagtttataa agcacagtga attcctggtc aatctctcca ctgaggcaat   2220

ttggaatcaa taagcaattg ataatagttt ggagtaaggg acttcatata cctgattcct   2280

ctagaaggct gtctaacata ccacatgatt acatgaactg tatggtatcc atctatctct   2340

gttctattga atgccttgtt aacagccaac actgaaaaca ctgtgagaat ttgttttcag   2400

gtctgacacc tttcagtctc tttttatagc aagaaatcaa tatccttttt ataaaaattc   2460

atgtctgtat ttcaggagca aactcttcag gctccttttt tataaactgg tgatttttct   2520

tttgtctaaa aaacacatga agaaaattta ccaaaaaaaa aaaaaaaagc agaagaataa   2580

tgtagtttag aaattatgct gtcactgcca aacagtaacc tccaggagaa aacaagatga   2640

atagcagagg ccaattcaat agaatcagtt ttttgatagc tttttaacag ttatgcttgc   2700

attaataatt tcaatgtgga ccagacattc taattatatt ttaaatgaaa tgttacagca   2760

tattttaagc aactcttttt atctataatc ctaatatttc atactgaaga cacagaaatc   2820

tttcacttgt ctttaacatt agaaaggatt tctctttact aaggactgat catttgaaat   2880

agttttcagt cttttgagat acaggtttat aacactgctt ttttttttct gtaatcatag   2940

cccataatgg caaagacaac taaatttaag tgaaggtcat gcatgccaat tctgtgtttg   3000

cttttagcag atatgaagat ttccttattt ctttgtaatt gtgcagatat tttgaaaggc   3060

acagcattcg aagccaagct gctgtttggc tactgaatgg cttgcagttg ttcctccact   3120

ctaaatggaa tgagcttgct gtgtgtgtgt gtggtggtgg tgggaggggg tggtgcatgt   3180

gtgtgtgtgt gtgtgcatct gcagctgctt caaaattagg aaatactaca ggacacccct   3240

gtaatggatt ggtggcaact gggtggcact gctgatgtgc actgtgtagg ggggaaccca   3300

gtggtggtgg ggtagctcag atgcccctag acaagcttca gatgtctgta gctaccagaa   3360

acattttcgg ttcaggaaaa gtgagatgat ggtagtactg gtttctggtg aaattgaaga   3420

accccaaatg atgaggatct ctttttgccc cctctccttt ttttgtagac ccattcaaaa   3480

ccattaataa gcccatttta ctaagcccct atttctttct agaagctcag ggttttctta   3540

gtgcctccca gaacattttg tagttaattg ggaaaaagtg atacttggat tagggggtgt   3600

gggcataaag aatggtggga ggcctgattt taaacttcag gccagaaccc ccaatgactc   3660

cacccatagt ctcactttag gtctcattta gtccatcacc tttattttaa gttgaggaag   3720

tggaggctgg taaagagcag gaccagagga agaatccaga tttccttatg cttgggcctc   3780

acactagctc tctgagtatt tccttgattg cggtatatgt actactagaa aataccaaat   3840

ggatatattt tctttaggat aacctttgaa ccaacaatct tcaataacaa tagtacatct   3900

tccatcttac ttttaatcga gtataaggaa atgtttcttt atggccattt tggagggagc   3960

aggggatgag gcttggcata gtccaaaatt taagtctcca ataattaatt gcattttaaa   4020

ttggcccact ttcaaggcaa ttttttttgt gtgtctgtaa ctgagctcct ccacccctgt   4080

cattcacttc caattttacc caatccaatt ttagcactca agttccattg tgttaatttc   4140

tgcacggtca acaaacatca agtcagcaag catttgccac cactccctat acttctccct   4200

ccttcttaca cacacacaca cacacacaca cacaatccat ctcttgcttg ttcctacctc   4260

ctgatttttc ttccctacag aaatagaaat agggacaaag aaggggaaaa tgtatatatt   4320

ggggctgggc tgaacaacta acttcataag tagtattaac taggggtaaa ttgagagaaa   4380

agctcctttt ctcttcactg ttttggaaag gatagccatt agcatgactg ctttgtgtcc   4440

ttatggactt tagtattagc ctagattgaa ttatagcgtt ttctagctgg aaggaacctt   4500

aagatcacat catctactcc tctactccaa atttctcatt cttcaggcca ggaaaccgag   4560

acacagaggt aaagtaattt ccccaaggtc acacagctgg ctggggcagg attgggttta   4620

caacccacat ctcctggctc ttattccagg gccttttccc actaagtagt attgccttcc   4680

attaggctcc tgagagttat ttctcagggt catgttgcat cttggagcca catgctgctg   4740

ccctgatctc agtgggaaat ccacccagca acctaataca gccccttttc cctgcattca   4800

cctggttccc atccacatgg gttgcagatg tccttgaaga gagtgaggca ttgagggcca   4860

ataggagcaa tggggtccct ggccttgtcc atctgattca ggagatcact gctccatcgt   4920

gaggagccct ctgaatagcc ccccactgaa tgcttgcctt gcccaaatgg aatggaggaa   4980

gattgatttt ctccatcagt tcaccttgtg tcatctcata atggttggtc tttccaggct   5040

gagggaaatg tttcttgttt ccagagtaga aaaagaaaga gtggaacaat agctttgttc   5100

atcctaactt tctgagatgg cttttcaaca ttttaaaaaa actagtgtgg ctaccattca   5160

ctggcaatga tttcttttag aatatgggag taagatgagc tagagaaaat aacctggtct   5220

cactgtggtt gccctcatcc acaatgtccc caaagccatc ctgctctgat gaggacaatt   5280

tccaggtata agcaaggggc tttgtgacaa aaatgtaccc tggctgatgt taaacattgg   5340

ctcctgtgtt tgcaccaaaa tagcaagctg tgtgctctat acactcttcc catcgtcttg   5400

tgtacactgc tcctgtggcc ttccacagca gaaaccaggg caaaagggtc caaacacatg   5460

gttttccttg ctgcaaggct cttcctggga actaaggggg tatttattag ttcagttcta   5520

agagacctcc ttctgggctt accccactcc tcaggtactt ctctctcctt cctccttctc   5580

ctccacagtc acaagtaacc aaggaacctg aaagtggatg tgtagctatt tgaagaaggc   5640

aaggaaccct gagattcttc tttgaatcct ctagtccaag tcttagacca gtgattggtg   5700

cttaccttga acaaaatttt gtctgtgttc ctaatccctt caatactctg ggtacaatgc   5760

tcccaatcac cctgcacatt tgattctaaa tggcttttat tttttaaaaa tccatatccc   5820

taggacaaga gaacaggatg cctatatccc caaaatgagc tccaggacac tgatgggaat   5880

gatcccaaag atcaccccac ctcagaaacg tctgtgccaa gagacttccc cagatagaaa   5940

cactgggaca gtggtttgaa cgacttcttt tatggttgtc cagtttgcta tggaaataaa   6000

aggcattgat tttttaaaaa gatgattgga acctgtcttt ggccacatag ggccacttgg   6060

atccatttcc aggccttact catatattgc cttcactgaa gggctttggc tttaagtccc   6120

agactggtct cccaagtgaa ccataagtgt tttggagctc atctggggtg aggcatgaga   6180

atgttgcccc atctatccct tcaggaaaag gtgccttccc tccctttctc ctaaagcctg   6240

gtccccagaa attgtttttg tctccaaaag tctagtatgg tctttataca cccagactct   6300

tagtgttgcg tcctgccttg tttccttgtt aaggatctat gcagacctcc cgctttggct   6360

tagctagcgt gacattggct atcatttgac aagactaact tttttttttt tttttttttg   6420

actgagtctc cctctgtcac ctaggctgga gtgcagtggc acaatcttgg ctcgctgcaa   6480

ccttcaccct tcacctccca ggtcgaagcg attctcctgc ctcagtctcc cgagtagctg   6540

ggattacagg cgtgcgccac caaatctggc tattttttta ttattattat ttttagtaga   6600

gatggggttt caccatgttg gccagactgg tcttgaactc ttggcctcaa attatctgcc   6660

cacctcggcc tcccaaagtg ctgggattac aggcatgagc caccatgccc agctgacaag   6720

actaattttt tatcccttgg tttattggct tcaacatctt ctggaatcag aggtgatttt   6780

ttcttacctt ggatgcctga gactagggga gtatagaatt ccaattggta attaaggcat   6840

ctttctgctc ctgatcagaa gggcaggtta gttgggagag gtcagatggc acaacagaag   6900

tcaccttgta agtaaggcaa agacttgaag gcattagcgt ttctcattac taggtcaata   6960

acctgaggga atcaatggct ttttgccgct ctacctcttg tgtatctctt tgacttttct   7020

ttctctgtct agtttcctct gttctcagtt tatattctat gttatcagtc tctctttcca   7080

cagtacaaac atccatcctt tctcctgtgc aattctgtct ctccctctta ttatctttat   7140

ttgtactttt tccttcctcc ctgtctaggc attgggcatg tgcctcttct tagcctgtga   7200

ttttgccttg ggactgatga taaattattt ccagattcaa tcagccctgg tcctacccca   7260

gtccaatcag aagtatgttg gtgggaatca acctgatcct ggccctttct tcttctccat   7320

tttcattcgt aatccccctc agcagatctt tacaagcagt ttccttatag ctcatgtatc   7380

tttaggtctt tgccttccaa gcactgtaca gaatactttg tggttccttt ttagtctgac   7440

attttgtgga gcagtgaagc gtgctcagag acataatcag ctgaagagaa aaaatccacc   7500

catggattta tatcagctaa atactaataa ttgattttgt ttgatgtgcc cataattttt   7560

aaagctgcaa tataatataa tgagggacca caggtaattt ctcctgtcat ttgttttggc   7620

tggatggggg tgggggagta attgcttaaa gttttaccat tacacattaa actctctata   7680

ataatcttgt ttggggcttg ctaactgttg agctgtttta actaaactgg taggcaatcg   7740

gagttgattt aaatgaaaag ataatttaac aaatctatac tataaaaaga gacatttgct   7800

taattgacat gtattttttc cttctgagtc acctaaacat ttactcttga caccaactgt   7860

tcatgatact gaatagacag tccatataag agaaattagt ggacctaaag aagccagatt   7920

gtaggtgtta atttattaaa cagagtgcaa agcccttgga aatgtcactg cttggcaata   7980

ccatatggaa tgccaaaatt tacaatgact tttctttata agttatccaa aagggatttg   8040

aacaagtaag aggttatgcc aaaatgtctc caatgtatgg tcctgtaata tattgcagct   8100

tgaagccaat gatcccttat gacttgtata caactaatgc atgttttatt gaattttgca   8160

tttcccacgt gtggtaagtt ctttaaaatg tttttgatca cctttttgtg ccattaaact   8220

tgtacagaaa atgtttttat ggccattttc aaagggagaa agtttaaaat ggaaacagcc   8280

caccctttct gccctatagc tgtagttaga attgagtacc tgtagcaaaa cagctgtaat   8340

tggtggttgt agtgttagag gtgttagctt gctagtgact agctttggag agtaaatgca   8400

tggtattgta catcacattt cttaactcgt tttaacctct gaaaagaata tattcttctt   8460

tgtagtcctt cttcccaccc ccttgccctc tccctctccc tgctcccagt tgtcttacag   8520

ttgtaaatat ctgatttgag gcccaataac tcttgccaag taaagtcagc aaacaacaaa   8580

caaaccaaaa tgtggggaaa aggcatttct caaccatctc tcagcagtta ttgatcattt   8640

cttaaggaac agcattgtga tcaaagactc aactttacgt aaaaatcagt ggtaaattgg   8700

ggttgtattt ggccatttga ttacatttca ggattgaata gttttcagaa tcacatgtaa   8760

tccaaagaca gtaggtagtg atgtccctta tccctgcagc tgttttaaga tagagacctc   8820

agaagactct gcttgaccga tgaccaataa ttatttgaaa aaaaaagaaa aaatgagaga   8880

aataaaacag atatttaaga actttagcca cctatttaga atagttatag ccagaaaaaa   8940

aaacaagggc atgagttcaa atgcattact atcagtgtcc taggcaatac ctaacctact   9000

ctgaaattgt gattcaaaag cagtatttca agaggcattc tccttttttg gtttgctgac   9060

cccacttgga ctggtaggtt tggtgaggcc cccataaacc agctggagca gacccttttc   9120

atctcctgtg cctgtaacac ccctcttccc ccaccccctc cgcaattcaa tgagggcttt   9180

cttgggtcag aggacttcaa ggttgtctag agaagtttgc catgtgtgta aggtgctgtg   9240

aactgtgagt gctgaagatt cgcagcattc aataccaggc agccaaagag ctgctcttgc   9300

aattattttg gctctcaagc tctgttcttc atcgcattct catttctgtg tacatttgca   9360

agatgtgtgt aatgtcattt tccaaaaata aaatttgatt tcaata                  9406


<210>  10618
<211>  441
<212>  PRT
<213>  Homo sapiens

<400>  10618

Met Lys Thr Leu Pro Leu His Ser His Cys Thr Glu Met Gln Arg Leu 
1               5                   10                  15


Leu Pro Lys Leu Glu Met Leu Thr Leu Gly Ser Ser Phe Cys Ser Leu 
            20                  25                  30


Gln Gly Glu Phe Cys Gln Ala Met Asp Ser Phe Thr Thr Val Ser His 
        35                  40                  45


Val Gly Met Cys Glu Glu Thr Asp Ala Ser Phe Asn Val Phe Ser Pro 
    50                  55                  60


Lys Phe Gln Phe Asp Arg Ser His Cys Gln Ser Leu Arg Phe His Gln 
65                  70                  75                  80


Asn Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser 
                85                  90                  95


Arg Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His 
            100                 105                 110


Ser Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser 
        115                 120                 125


Asn Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg 
    130                 135                 140


Tyr Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser 
145                 150                 155                 160


Phe Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile 
                165                 170                 175


Asn Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg 
            180                 185                 190


Lys Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys 
        195                 200                 205


Ser Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn 
    210                 215                 220


Pro Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro 
225                 230                 235                 240


Gln Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp 
                245                 250                 255


Phe Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro 
            260                 265                 270


Arg Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe 
        275                 280                 285


Glu Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly 
    290                 295                 300


Val Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu 
305                 310                 315                 320


His Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu 
                325                 330                 335


Lys Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys 
            340                 345                 350


Arg Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser 
        355                 360                 365


Pro Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg 
    370                 375                 380


Ser Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu 
385                 390                 395                 400


Ser Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro 
                405                 410                 415


Gly Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp 
            420                 425                 430


Asp Ser Asp Ser Leu Gly Asp Ser Met 
        435                 440


<210>  10619
<211>  9219
<212>  DNA
<213>  Homo sapiens

<400>  10619
ctttctctca gcatctccac ccaaccagca gaaaaccggt gagtggggct tttaagtgat     60

tttcaagaag aatgtaacag atgtcaaacg ggaaaagcac aaggcaaagc ctgctctctc    120

tgtctctctg tctcctcttc tccttttttg ccttattcta tccgattttt tccctaagct    180

tctacctggg attttccttt ggaaaagtct ctgaggttcc accaaaatat ggaacttgat    240

tttggacact ttgacgaaag agataagaca tccaggaaca tgcgaggctc ccggatgaat    300

gggttgccta gccccactca cagcgcccac tgtagcttct accgaaccag aaccttgcag    360

gcactgagta atgagaagaa agccaagaag gtacgtttct accgcaatgg ggaccgctac    420

ttcaagggga ttgtgtacgc tgtgtcctct gaccgttttc gcagctttga cgccttgctg    480

gctgacctga cgcgatctct gtctgacaac atcaacctgc ctcagggagt gcgttacatt    540

tacaccattg atggatccag gaagatcgga agcatggatg aactggagga aggggaaagc    600

tatgtctgtt cctcagacaa cttctttaaa aaggtggagt acaccaagaa tgtcaatccc    660

aactggtctg tcaacgtaaa aacatctgcc aatatgaaag ccccccagtc cttggctagc    720

agcaacagtg cacaggccag ggagaacaag gactttgtgc gccccaagct ggttaccatc    780

atccgcagtg gggtgaagcc tcggaaggct gtgcgtgtgc ttctgaacaa gaagacagcc    840

cactcttttg agcaagtcct cactgatatc acagaagcca tcaaactgga gaccggggtt    900

gtcaaaaaac tctacactct ggatggaaaa caggtaactt gtctccatga tttctttggt    960

gatgatgatg tgtttattgc ctgtggtcct gaaaaatttc gctatgctca ggatgatttt   1020

tctctggatg aaaatgaatg ccgagtcatg aagggaaacc catcagccac agctggccca   1080

aaggcatccc caacacctca gaagacttca gccaagagcc ctggtcctat gcgccgaagc   1140

aagtctccag ctgactcagc aaacggaacc tccagcagcc agctctctac ccccaagtct   1200

aagcagtctc ccatctctac gcccaccagt cctggcagcc tccggaagca caaggacctg   1260

tacctgcctc tgtccttgga tgactcggac tcgcttggtg attccatgta aaggagggga   1320

gagtgctcag agtccagagt acaaatccaa gcctatcatt gtagtagggt acttctgctc   1380

aagtgtccaa cagggctatt ggtgctttca agtttttatt ttgttgttgt tgttattttg   1440

aaaaacacat tgtaatatgt tgggtttatt ttcctgtgat ttctcctctg ggccactgat   1500

ccacagttac caattatgag agatagattg ataaccatcc tttggggcag cattccaggg   1560

atgcaaaatg tgctagtcca tgacctttca atggaaagct taggtgcctg cgttatattt   1620

gccctgtcta attttgccca tacagtcttc cttctgtaga gggctgttta catatacagc   1680

acttaaaatg tttgtgtggg aaaaaaaaaa ctcattggca gatccaagaa tgacaaacac   1740

aagtgcccct tttctctgga tctcaagaat ggtggaggac cctggaagga cagcaaggca   1800

gctccccagc ctcactcttc actcctgatt gaggcccggg tttgttgtcc agcaccaatt   1860

ctggctgtca atggggagaa ataaaccaac aacttataat tgtgacacca gatgcttagg   1920

atcctggtgc tgggttagct aagagaatag acagaattgg aaaatactgc agacatttcc   1980

gaagagttta taaagcacag tgaattcctg gtcaatctct ccactgaggc aatttggaat   2040

caataagcaa ttgataatag tttggagtaa gggacttcat atacctgatt cctctagaag   2100

gctgtctaac ataccacatg attacatgaa ctgtatggta tccatctatc tctgttctat   2160

tgaatgcctt gttaacagcc aacactgaaa acactgtgag aatttgtttt caggtctgac   2220

acctttcagt ctctttttat agcaagaaat caatatcctt tttataaaaa ttcatgtctg   2280

tatttcagga gcaaactctt caggctcctt ttttataaac tggtgatttt tcttttgtct   2340

aaaaaacaca tgaagaaaat ttaccaaaaa aaaaaaaaaa agcagaagaa taatgtagtt   2400

tagaaattat gctgtcactg ccaaacagta acctccagga gaaaacaaga tgaatagcag   2460

aggccaattc aatagaatca gttttttgat agctttttaa cagttatgct tgcattaata   2520

atttcaatgt ggaccagaca ttctaattat attttaaatg aaatgttaca gcatatttta   2580

agcaactctt tttatctata atcctaatat ttcatactga agacacagaa atctttcact   2640

tgtctttaac attagaaagg atttctcttt actaaggact gatcatttga aatagttttc   2700

agtcttttga gatacaggtt tataacactg cttttttttt tctgtaatca tagcccataa   2760

tggcaaagac aactaaattt aagtgaaggt catgcatgcc aattctgtgt ttgcttttag   2820

cagatatgaa gatttcctta tttctttgta attgtgcaga tattttgaaa ggcacagcat   2880

tcgaagccaa gctgctgttt ggctactgaa tggcttgcag ttgttcctcc actctaaatg   2940

gaatgagctt gctgtgtgtg tgtgtggtgg tggtgggagg gggtggtgca tgtgtgtgtg   3000

tgtgtgtgca tctgcagctg cttcaaaatt aggaaatact acaggacacc cctgtaatgg   3060

attggtggca actgggtggc actgctgatg tgcactgtgt aggggggaac ccagtggtgg   3120

tggggtagct cagatgcccc tagacaagct tcagatgtct gtagctacca gaaacatttt   3180

cggttcagga aaagtgagat gatggtagta ctggtttctg gtgaaattga agaaccccaa   3240

atgatgagga tctctttttg ccccctctcc tttttttgta gacccattca aaaccattaa   3300

taagcccatt ttactaagcc cctatttctt tctagaagct cagggttttc ttagtgcctc   3360

ccagaacatt ttgtagttaa ttgggaaaaa gtgatacttg gattaggggg tgtgggcata   3420

aagaatggtg ggaggcctga ttttaaactt caggccagaa cccccaatga ctccacccat   3480

agtctcactt taggtctcat ttagtccatc acctttattt taagttgagg aagtggaggc   3540

tggtaaagag caggaccaga ggaagaatcc agatttcctt atgcttgggc ctcacactag   3600

ctctctgagt atttccttga ttgcggtata tgtactacta gaaaatacca aatggatata   3660

ttttctttag gataaccttt gaaccaacaa tcttcaataa caatagtaca tcttccatct   3720

tacttttaat cgagtataag gaaatgtttc tttatggcca ttttggaggg agcaggggat   3780

gaggcttggc atagtccaaa atttaagtct ccaataatta attgcatttt aaattggccc   3840

actttcaagg caattttttt tgtgtgtctg taactgagct cctccacccc tgtcattcac   3900

ttccaatttt acccaatcca attttagcac tcaagttcca ttgtgttaat ttctgcacgg   3960

tcaacaaaca tcaagtcagc aagcatttgc caccactccc tatacttctc cctccttctt   4020

acacacacac acacacacac acacacaatc catctcttgc ttgttcctac ctcctgattt   4080

ttcttcccta cagaaataga aatagggaca aagaagggga aaatgtatat attggggctg   4140

ggctgaacaa ctaacttcat aagtagtatt aactaggggt aaattgagag aaaagctcct   4200

tttctcttca ctgttttgga aaggatagcc attagcatga ctgctttgtg tccttatgga   4260

ctttagtatt agcctagatt gaattatagc gttttctagc tggaaggaac cttaagatca   4320

catcatctac tcctctactc caaatttctc attcttcagg ccaggaaacc gagacacaga   4380

ggtaaagtaa tttccccaag gtcacacagc tggctggggc aggattgggt ttacaaccca   4440

catctcctgg ctcttattcc agggcctttt cccactaagt agtattgcct tccattaggc   4500

tcctgagagt tatttctcag ggtcatgttg catcttggag ccacatgctg ctgccctgat   4560

ctcagtggga aatccaccca gcaacctaat acagcccctt ttccctgcat tcacctggtt   4620

cccatccaca tgggttgcag atgtccttga agagagtgag gcattgaggg ccaataggag   4680

caatggggtc cctggccttg tccatctgat tcaggagatc actgctccat cgtgaggagc   4740

cctctgaata gccccccact gaatgcttgc cttgcccaaa tggaatggag gaagattgat   4800

tttctccatc agttcacctt gtgtcatctc ataatggttg gtctttccag gctgagggaa   4860

atgtttcttg tttccagagt agaaaaagaa agagtggaac aatagctttg ttcatcctaa   4920

ctttctgaga tggcttttca acattttaaa aaaactagtg tggctaccat tcactggcaa   4980

tgatttcttt tagaatatgg gagtaagatg agctagagaa aataacctgg tctcactgtg   5040

gttgccctca tccacaatgt ccccaaagcc atcctgctct gatgaggaca atttccaggt   5100

ataagcaagg ggctttgtga caaaaatgta ccctggctga tgttaaacat tggctcctgt   5160

gtttgcacca aaatagcaag ctgtgtgctc tatacactct tcccatcgtc ttgtgtacac   5220

tgctcctgtg gccttccaca gcagaaacca gggcaaaagg gtccaaacac atggttttcc   5280

ttgctgcaag gctcttcctg ggaactaagg gggtatttat tagttcagtt ctaagagacc   5340

tccttctggg cttaccccac tcctcaggta cttctctctc cttcctcctt ctcctccaca   5400

gtcacaagta accaaggaac ctgaaagtgg atgtgtagct atttgaagaa ggcaaggaac   5460

cctgagattc ttctttgaat cctctagtcc aagtcttaga ccagtgattg gtgcttacct   5520

tgaacaaaat tttgtctgtg ttcctaatcc cttcaatact ctgggtacaa tgctcccaat   5580

caccctgcac atttgattct aaatggcttt tattttttaa aaatccatat ccctaggaca   5640

agagaacagg atgcctatat ccccaaaatg agctccagga cactgatggg aatgatccca   5700

aagatcaccc cacctcagaa acgtctgtgc caagagactt ccccagatag aaacactggg   5760

acagtggttt gaacgacttc ttttatggtt gtccagtttg ctatggaaat aaaaggcatt   5820

gattttttaa aaagatgatt ggaacctgtc tttggccaca tagggccact tggatccatt   5880

tccaggcctt actcatatat tgccttcact gaagggcttt ggctttaagt cccagactgg   5940

tctcccaagt gaaccataag tgttttggag ctcatctggg gtgaggcatg agaatgttgc   6000

cccatctatc ccttcaggaa aaggtgcctt ccctcccttt ctcctaaagc ctggtcccca   6060

gaaattgttt ttgtctccaa aagtctagta tggtctttat acacccagac tcttagtgtt   6120

gcgtcctgcc ttgtttcctt gttaaggatc tatgcagacc tcccgctttg gcttagctag   6180

cgtgacattg gctatcattt gacaagacta actttttttt tttttttttt ttgactgagt   6240

ctccctctgt cacctaggct ggagtgcagt ggcacaatct tggctcgctg caaccttcac   6300

ccttcacctc ccaggtcgaa gcgattctcc tgcctcagtc tcccgagtag ctgggattac   6360

aggcgtgcgc caccaaatct ggctattttt ttattattat tatttttagt agagatgggg   6420

tttcaccatg ttggccagac tggtcttgaa ctcttggcct caaattatct gcccacctcg   6480

gcctcccaaa gtgctgggat tacaggcatg agccaccatg cccagctgac aagactaatt   6540

ttttatccct tggtttattg gcttcaacat cttctggaat cagaggtgat tttttcttac   6600

cttggatgcc tgagactagg ggagtataga attccaattg gtaattaagg catctttctg   6660

ctcctgatca gaagggcagg ttagttggga gaggtcagat ggcacaacag aagtcacctt   6720

gtaagtaagg caaagacttg aaggcattag cgtttctcat tactaggtca ataacctgag   6780

ggaatcaatg gctttttgcc gctctacctc ttgtgtatct ctttgacttt tctttctctg   6840

tctagtttcc tctgttctca gtttatattc tatgttatca gtctctcttt ccacagtaca   6900

aacatccatc ctttctcctg tgcaattctg tctctccctc ttattatctt tatttgtact   6960

ttttccttcc tccctgtcta ggcattgggc atgtgcctct tcttagcctg tgattttgcc   7020

ttgggactga tgataaatta tttccagatt caatcagccc tggtcctacc ccagtccaat   7080

cagaagtatg ttggtgggaa tcaacctgat cctggccctt tcttcttctc cattttcatt   7140

cgtaatcccc ctcagcagat ctttacaagc agtttcctta tagctcatgt atctttaggt   7200

ctttgccttc caagcactgt acagaatact ttgtggttcc tttttagtct gacattttgt   7260

ggagcagtga agcgtgctca gagacataat cagctgaaga gaaaaaatcc acccatggat   7320

ttatatcagc taaatactaa taattgattt tgtttgatgt gcccataatt tttaaagctg   7380

caatataata taatgaggga ccacaggtaa tttctcctgt catttgtttt ggctggatgg   7440

gggtggggga gtaattgctt aaagttttac cattacacat taaactctct ataataatct   7500

tgtttggggc ttgctaactg ttgagctgtt ttaactaaac tggtaggcaa tcggagttga   7560

tttaaatgaa aagataattt aacaaatcta tactataaaa agagacattt gcttaattga   7620

catgtatttt ttccttctga gtcacctaaa catttactct tgacaccaac tgttcatgat   7680

actgaataga cagtccatat aagagaaatt agtggaccta aagaagccag attgtaggtg   7740

ttaatttatt aaacagagtg caaagccctt ggaaatgtca ctgcttggca ataccatatg   7800

gaatgccaaa atttacaatg acttttcttt ataagttatc caaaagggat ttgaacaagt   7860

aagaggttat gccaaaatgt ctccaatgta tggtcctgta atatattgca gcttgaagcc   7920

aatgatccct tatgacttgt atacaactaa tgcatgtttt attgaatttt gcatttccca   7980

cgtgtggtaa gttctttaaa atgtttttga tcaccttttt gtgccattaa acttgtacag   8040

aaaatgtttt tatggccatt ttcaaaggga gaaagtttaa aatggaaaca gcccaccctt   8100

tctgccctat agctgtagtt agaattgagt acctgtagca aaacagctgt aattggtggt   8160

tgtagtgtta gaggtgttag cttgctagtg actagctttg gagagtaaat gcatggtatt   8220

gtacatcaca tttcttaact cgttttaacc tctgaaaaga atatattctt ctttgtagtc   8280

cttcttccca cccccttgcc ctctccctct ccctgctccc agttgtctta cagttgtaaa   8340

tatctgattt gaggcccaat aactcttgcc aagtaaagtc agcaaacaac aaacaaacca   8400

aaatgtgggg aaaaggcatt tctcaaccat ctctcagcag ttattgatca tttcttaagg   8460

aacagcattg tgatcaaaga ctcaacttta cgtaaaaatc agtggtaaat tggggttgta   8520

tttggccatt tgattacatt tcaggattga atagttttca gaatcacatg taatccaaag   8580

acagtaggta gtgatgtccc ttatccctgc agctgtttta agatagagac ctcagaagac   8640

tctgcttgac cgatgaccaa taattatttg aaaaaaaaag aaaaaatgag agaaataaaa   8700

cagatattta agaactttag ccacctattt agaatagtta tagccagaaa aaaaaacaag   8760

ggcatgagtt caaatgcatt actatcagtg tcctaggcaa tacctaacct actctgaaat   8820

tgtgattcaa aagcagtatt tcaagaggca ttctcctttt ttggtttgct gaccccactt   8880

ggactggtag gtttggtgag gcccccataa accagctgga gcagaccctt ttcatctcct   8940

gtgcctgtaa cacccctctt cccccacccc ctccgcaatt caatgagggc tttcttgggt   9000

cagaggactt caaggttgtc tagagaagtt tgccatgtgt gtaaggtgct gtgaactgtg   9060

agtgctgaag attcgcagca ttcaatacca ggcagccaaa gagctgctct tgcaattatt   9120

ttggctctca agctctgttc ttcatcgcat tctcatttct gtgtacattt gcaagatgtg   9180

tgtaatgtca ttttccaaaa ataaaatttg atttcaata                          9219


<210>  10620
<211>  360
<212>  PRT
<213>  Homo sapiens

<400>  10620

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300


Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu Ser 
305                 310                 315                 320


Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro Gly 
                325                 330                 335


Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp Asp 
            340                 345                 350


Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360


<210>  10621
<211>  9108
<212>  DNA
<213>  Homo sapiens

<400>  10621
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt     60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg    120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc    180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga    240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg    300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac    360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg    420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa    480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat    540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc    600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg    660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag    720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag    780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat    840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag    900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca    960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg   1020

cgccgaagca agtctccagc tgactcagca aacggaacct ccagcagcca gctctctacc   1080

cccaagtcta agcagtctcc catctctacg cccaccagtc ctggcagcct ccggaagcac   1140

aaggacctgt acctgcctct gtccttggat gactcggact cgcttggtga ttccatgtaa   1200

aggaggggag agtgctcaga gtccagagta caaatccaag cctatcattg tagtagggta   1260

cttctgctca agtgtccaac agggctattg gtgctttcaa gtttttattt tgttgttgtt   1320

gttattttga aaaacacatt gtaatatgtt gggtttattt tcctgtgatt tctcctctgg   1380

gccactgatc cacagttacc aattatgaga gatagattga taaccatcct ttggggcagc   1440

attccaggga tgcaaaatgt gctagtccat gacctttcaa tggaaagctt aggtgcctgc   1500

gttatatttg ccctgtctaa ttttgcccat acagtcttcc ttctgtagag ggctgtttac   1560

atatacagca cttaaaatgt ttgtgtggga aaaaaaaaac tcattggcag atccaagaat   1620

gacaaacaca agtgcccctt ttctctggat ctcaagaatg gtggaggacc ctggaaggac   1680

agcaaggcag ctccccagcc tcactcttca ctcctgattg aggcccgggt ttgttgtcca   1740

gcaccaattc tggctgtcaa tggggagaaa taaaccaaca acttataatt gtgacaccag   1800

atgcttagga tcctggtgct gggttagcta agagaataga cagaattgga aaatactgca   1860

gacatttccg aagagtttat aaagcacagt gaattcctgg tcaatctctc cactgaggca   1920

atttggaatc aataagcaat tgataatagt ttggagtaag ggacttcata tacctgattc   1980

ctctagaagg ctgtctaaca taccacatga ttacatgaac tgtatggtat ccatctatct   2040

ctgttctatt gaatgccttg ttaacagcca acactgaaaa cactgtgaga atttgttttc   2100

aggtctgaca cctttcagtc tctttttata gcaagaaatc aatatccttt ttataaaaat   2160

tcatgtctgt atttcaggag caaactcttc aggctccttt tttataaact ggtgattttt   2220

cttttgtcta aaaaacacat gaagaaaatt taccaaaaaa aaaaaaaaaa gcagaagaat   2280

aatgtagttt agaaattatg ctgtcactgc caaacagtaa cctccaggag aaaacaagat   2340

gaatagcaga ggccaattca atagaatcag ttttttgata gctttttaac agttatgctt   2400

gcattaataa tttcaatgtg gaccagacat tctaattata ttttaaatga aatgttacag   2460

catattttaa gcaactcttt ttatctataa tcctaatatt tcatactgaa gacacagaaa   2520

tctttcactt gtctttaaca ttagaaagga tttctcttta ctaaggactg atcatttgaa   2580

atagttttca gtcttttgag atacaggttt ataacactgc tttttttttt ctgtaatcat   2640

agcccataat ggcaaagaca actaaattta agtgaaggtc atgcatgcca attctgtgtt   2700

tgcttttagc agatatgaag atttccttat ttctttgtaa ttgtgcagat attttgaaag   2760

gcacagcatt cgaagccaag ctgctgtttg gctactgaat ggcttgcagt tgttcctcca   2820

ctctaaatgg aatgagcttg ctgtgtgtgt gtgtggtggt ggtgggaggg ggtggtgcat   2880

gtgtgtgtgt gtgtgtgcat ctgcagctgc ttcaaaatta ggaaatacta caggacaccc   2940

ctgtaatgga ttggtggcaa ctgggtggca ctgctgatgt gcactgtgta ggggggaacc   3000

cagtggtggt ggggtagctc agatgcccct agacaagctt cagatgtctg tagctaccag   3060

aaacattttc ggttcaggaa aagtgagatg atggtagtac tggtttctgg tgaaattgaa   3120

gaaccccaaa tgatgaggat ctctttttgc cccctctcct ttttttgtag acccattcaa   3180

aaccattaat aagcccattt tactaagccc ctatttcttt ctagaagctc agggttttct   3240

tagtgcctcc cagaacattt tgtagttaat tgggaaaaag tgatacttgg attagggggt   3300

gtgggcataa agaatggtgg gaggcctgat tttaaacttc aggccagaac ccccaatgac   3360

tccacccata gtctcacttt aggtctcatt tagtccatca cctttatttt aagttgagga   3420

agtggaggct ggtaaagagc aggaccagag gaagaatcca gatttcctta tgcttgggcc   3480

tcacactagc tctctgagta tttccttgat tgcggtatat gtactactag aaaataccaa   3540

atggatatat tttctttagg ataacctttg aaccaacaat cttcaataac aatagtacat   3600

cttccatctt acttttaatc gagtataagg aaatgtttct ttatggccat tttggaggga   3660

gcaggggatg aggcttggca tagtccaaaa tttaagtctc caataattaa ttgcatttta   3720

aattggccca ctttcaaggc aatttttttt gtgtgtctgt aactgagctc ctccacccct   3780

gtcattcact tccaatttta cccaatccaa ttttagcact caagttccat tgtgttaatt   3840

tctgcacggt caacaaacat caagtcagca agcatttgcc accactccct atacttctcc   3900

ctccttctta cacacacaca cacacacaca cacacaatcc atctcttgct tgttcctacc   3960

tcctgatttt tcttccctac agaaatagaa atagggacaa agaaggggaa aatgtatata   4020

ttggggctgg gctgaacaac taacttcata agtagtatta actaggggta aattgagaga   4080

aaagctcctt ttctcttcac tgttttggaa aggatagcca ttagcatgac tgctttgtgt   4140

ccttatggac tttagtatta gcctagattg aattatagcg ttttctagct ggaaggaacc   4200

ttaagatcac atcatctact cctctactcc aaatttctca ttcttcaggc caggaaaccg   4260

agacacagag gtaaagtaat ttccccaagg tcacacagct ggctggggca ggattgggtt   4320

tacaacccac atctcctggc tcttattcca gggccttttc ccactaagta gtattgcctt   4380

ccattaggct cctgagagtt atttctcagg gtcatgttgc atcttggagc cacatgctgc   4440

tgccctgatc tcagtgggaa atccacccag caacctaata cagccccttt tccctgcatt   4500

cacctggttc ccatccacat gggttgcaga tgtccttgaa gagagtgagg cattgagggc   4560

caataggagc aatggggtcc ctggccttgt ccatctgatt caggagatca ctgctccatc   4620

gtgaggagcc ctctgaatag ccccccactg aatgcttgcc ttgcccaaat ggaatggagg   4680

aagattgatt ttctccatca gttcaccttg tgtcatctca taatggttgg tctttccagg   4740

ctgagggaaa tgtttcttgt ttccagagta gaaaaagaaa gagtggaaca atagctttgt   4800

tcatcctaac tttctgagat ggcttttcaa cattttaaaa aaactagtgt ggctaccatt   4860

cactggcaat gatttctttt agaatatggg agtaagatga gctagagaaa ataacctggt   4920

ctcactgtgg ttgccctcat ccacaatgtc cccaaagcca tcctgctctg atgaggacaa   4980

tttccaggta taagcaaggg gctttgtgac aaaaatgtac cctggctgat gttaaacatt   5040

ggctcctgtg tttgcaccaa aatagcaagc tgtgtgctct atacactctt cccatcgtct   5100

tgtgtacact gctcctgtgg ccttccacag cagaaaccag ggcaaaaggg tccaaacaca   5160

tggttttcct tgctgcaagg ctcttcctgg gaactaaggg ggtatttatt agttcagttc   5220

taagagacct ccttctgggc ttaccccact cctcaggtac ttctctctcc ttcctccttc   5280

tcctccacag tcacaagtaa ccaaggaacc tgaaagtgga tgtgtagcta tttgaagaag   5340

gcaaggaacc ctgagattct tctttgaatc ctctagtcca agtcttagac cagtgattgg   5400

tgcttacctt gaacaaaatt ttgtctgtgt tcctaatccc ttcaatactc tgggtacaat   5460

gctcccaatc accctgcaca tttgattcta aatggctttt attttttaaa aatccatatc   5520

cctaggacaa gagaacagga tgcctatatc cccaaaatga gctccaggac actgatggga   5580

atgatcccaa agatcacccc acctcagaaa cgtctgtgcc aagagacttc cccagataga   5640

aacactggga cagtggtttg aacgacttct tttatggttg tccagtttgc tatggaaata   5700

aaaggcattg attttttaaa aagatgattg gaacctgtct ttggccacat agggccactt   5760

ggatccattt ccaggcctta ctcatatatt gccttcactg aagggctttg gctttaagtc   5820

ccagactggt ctcccaagtg aaccataagt gttttggagc tcatctgggg tgaggcatga   5880

gaatgttgcc ccatctatcc cttcaggaaa aggtgccttc cctccctttc tcctaaagcc   5940

tggtccccag aaattgtttt tgtctccaaa agtctagtat ggtctttata cacccagact   6000

cttagtgttg cgtcctgcct tgtttccttg ttaaggatct atgcagacct cccgctttgg   6060

cttagctagc gtgacattgg ctatcatttg acaagactaa cttttttttt tttttttttt   6120

tgactgagtc tccctctgtc acctaggctg gagtgcagtg gcacaatctt ggctcgctgc   6180

aaccttcacc cttcacctcc caggtcgaag cgattctcct gcctcagtct cccgagtagc   6240

tgggattaca ggcgtgcgcc accaaatctg gctatttttt tattattatt atttttagta   6300

gagatggggt ttcaccatgt tggccagact ggtcttgaac tcttggcctc aaattatctg   6360

cccacctcgg cctcccaaag tgctgggatt acaggcatga gccaccatgc ccagctgaca   6420

agactaattt tttatccctt ggtttattgg cttcaacatc ttctggaatc agaggtgatt   6480

ttttcttacc ttggatgcct gagactaggg gagtatagaa ttccaattgg taattaaggc   6540

atctttctgc tcctgatcag aagggcaggt tagttgggag aggtcagatg gcacaacaga   6600

agtcaccttg taagtaaggc aaagacttga aggcattagc gtttctcatt actaggtcaa   6660

taacctgagg gaatcaatgg ctttttgccg ctctacctct tgtgtatctc tttgactttt   6720

ctttctctgt ctagtttcct ctgttctcag tttatattct atgttatcag tctctctttc   6780

cacagtacaa acatccatcc tttctcctgt gcaattctgt ctctccctct tattatcttt   6840

atttgtactt tttccttcct ccctgtctag gcattgggca tgtgcctctt cttagcctgt   6900

gattttgcct tgggactgat gataaattat ttccagattc aatcagccct ggtcctaccc   6960

cagtccaatc agaagtatgt tggtgggaat caacctgatc ctggcccttt cttcttctcc   7020

attttcattc gtaatccccc tcagcagatc tttacaagca gtttccttat agctcatgta   7080

tctttaggtc tttgccttcc aagcactgta cagaatactt tgtggttcct ttttagtctg   7140

acattttgtg gagcagtgaa gcgtgctcag agacataatc agctgaagag aaaaaatcca   7200

cccatggatt tatatcagct aaatactaat aattgatttt gtttgatgtg cccataattt   7260

ttaaagctgc aatataatat aatgagggac cacaggtaat ttctcctgtc atttgttttg   7320

gctggatggg ggtgggggag taattgctta aagttttacc attacacatt aaactctcta   7380

taataatctt gtttggggct tgctaactgt tgagctgttt taactaaact ggtaggcaat   7440

cggagttgat ttaaatgaaa agataattta acaaatctat actataaaaa gagacatttg   7500

cttaattgac atgtattttt tccttctgag tcacctaaac atttactctt gacaccaact   7560

gttcatgata ctgaatagac agtccatata agagaaatta gtggacctaa agaagccaga   7620

ttgtaggtgt taatttatta aacagagtgc aaagcccttg gaaatgtcac tgcttggcaa   7680

taccatatgg aatgccaaaa tttacaatga cttttcttta taagttatcc aaaagggatt   7740

tgaacaagta agaggttatg ccaaaatgtc tccaatgtat ggtcctgtaa tatattgcag   7800

cttgaagcca atgatccctt atgacttgta tacaactaat gcatgtttta ttgaattttg   7860

catttcccac gtgtggtaag ttctttaaaa tgtttttgat cacctttttg tgccattaaa   7920

cttgtacaga aaatgttttt atggccattt tcaaagggag aaagtttaaa atggaaacag   7980

cccacccttt ctgccctata gctgtagtta gaattgagta cctgtagcaa aacagctgta   8040

attggtggtt gtagtgttag aggtgttagc ttgctagtga ctagctttgg agagtaaatg   8100

catggtattg tacatcacat ttcttaactc gttttaacct ctgaaaagaa tatattcttc   8160

tttgtagtcc ttcttcccac ccccttgccc tctccctctc cctgctccca gttgtcttac   8220

agttgtaaat atctgatttg aggcccaata actcttgcca agtaaagtca gcaaacaaca   8280

aacaaaccaa aatgtgggga aaaggcattt ctcaaccatc tctcagcagt tattgatcat   8340

ttcttaagga acagcattgt gatcaaagac tcaactttac gtaaaaatca gtggtaaatt   8400

ggggttgtat ttggccattt gattacattt caggattgaa tagttttcag aatcacatgt   8460

aatccaaaga cagtaggtag tgatgtccct tatccctgca gctgttttaa gatagagacc   8520

tcagaagact ctgcttgacc gatgaccaat aattatttga aaaaaaaaga aaaaatgaga   8580

gaaataaaac agatatttaa gaactttagc cacctattta gaatagttat agccagaaaa   8640

aaaaacaagg gcatgagttc aaatgcatta ctatcagtgt cctaggcaat acctaaccta   8700

ctctgaaatt gtgattcaaa agcagtattt caagaggcat tctccttttt tggtttgctg   8760

accccacttg gactggtagg tttggtgagg cccccataaa ccagctggag cagacccttt   8820

tcatctcctg tgcctgtaac acccctcttc ccccaccccc tccgcaattc aatgagggct   8880

ttcttgggtc agaggacttc aaggttgtct agagaagttt gccatgtgtg taaggtgctg   8940

tgaactgtga gtgctgaaga ttcgcagcat tcaataccag gcagccaaag agctgctctt   9000

gcaattattt tggctctcaa gctctgttct tcatcgcatt ctcatttctg tgtacatttg   9060

caagatgtgt gtaatgtcat tttccaaaaa taaaatttga tttcaata                9108


<210>  10622
<211>  360
<212>  PRT
<213>  Homo sapiens

<400>  10622

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300


Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu Ser 
305                 310                 315                 320


Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro Gly 
                325                 330                 335


Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp Asp 
            340                 345                 350


Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360


<210>  10623
<211>  2254
<212>  DNA
<213>  Homo sapiens

<400>  10623
ctggcaggaa tttcttgctt ggagctcaga caacaaaggc atagagagat tggttttctt     60

tctctcagca tctccaccca accagcagaa aaccggtctc tgaggttcca ccaaaatatg    120

gaacttgatt ttggacactt tgacgaaaga gataagacat ccaggaacat gcgaggctcc    180

cggatgaatg ggttgcctag ccccactcac agcgcccact gtagcttcta ccgaaccaga    240

accttgcagg cactgagtaa tgagaagaaa gccaagaagg tacgtttcta ccgcaatggg    300

gaccgctact tcaaggggat tgtgtacgct gtgtcctctg accgttttcg cagctttgac    360

gccttgctgg ctgacctgac gcgatctctg tctgacaaca tcaacctgcc tcagggagtg    420

cgttacattt acaccattga tggatccagg aagatcggaa gcatggatga actggaggaa    480

ggggaaagct atgtctgttc ctcagacaac ttctttaaaa aggtggagta caccaagaat    540

gtcaatccca actggtctgt caacgtaaaa acatctgcca atatgaaagc cccccagtcc    600

ttggctagca gcaacagtgc acaggccagg gagaacaagg actttgtgcg ccccaagctg    660

gttaccatca tccgcagtgg ggtgaagcct cggaaggctg tgcgtgtgct tctgaacaag    720

aagacagccc actcttttga gcaagtcctc actgatatca cagaagccat caaactggag    780

accggggttg tcaaaaaact ctacactctg gatggaaaac aggtaacttg tctccatgat    840

ttctttggtg atgatgatgt gtttattgcc tgtggtcctg aaaaatttcg ctatgctcag    900

gatgattttt ctctggatga aaatgaatgc cgagtcatga agggaaaccc atcagccaca    960

gctggcccaa aggcatcccc aacacctcag aagacttcag ccaagagccc tggtcctatg   1020

cgccgaagca agtctccagc tgactcagca aacggaacct ccagcagcca gctctctacc   1080

cccaagtcta agcagtctcc catctctacg cccaccagtc ctggcagcct ccggaagcac   1140

aaggacctgt acctgcctct gtccttggat gactcggact cgcttggtga ttccatgtaa   1200

aggaggggag agtgctcaga gtccagagta caaatccaag cctatcattg tagtagggta   1260

cttctgctca agtgtccaac agggctattg gtgctttcaa gtttttattt tgttgttgtt   1320

gttattttga aaaacacatt gtaatatgtt gggtttattt tcctgtgatt tctcctctgg   1380

gccactgatc cacagttacc aattatgaga gatagattga taaccatcct ttggggcagc   1440

attccaggga tgcaaaatgt gctagtccat gacctttcaa tggaaagctt aggtgcctgc   1500

gttatatttg ccctgtctaa ttttgcccat acagtcttcc ttctgtagag ggctgtttac   1560

atatacagca cttaaaatgt ttgtgtggga aaaaaaaaac tcattggcag atccaagaat   1620

gacaaacaca agtgcccctt ttctctggat ctcaagaatg gtggaggacc ctggaaggac   1680

agcaaggcag ctccccagcc tcactcttca ctcctgattg aggcccgggt ttgttgtcca   1740

gcaccaattc tggctgtcaa tggggagaaa taaaccaaca acttataatt gtgacaccag   1800

atgcttagga tcctggtgct gggttagcta agagaataga cagaattgga aaatactgca   1860

gacatttccg aagagtttat aaagcacagt gaattcctgg tcaatctctc cactgaggca   1920

atttggaatc aataagcaat tgataatagt ttggagtaag ggacttcata tacctgattc   1980

ctctagaagg ctgtctaaca taccacatga ttacatgaac tgtatggtat ccatctatct   2040

ctgttctatt gaatgccttg ttaacagcca acactgaaaa cactgtgaga atttgttttc   2100

aggtctgaca cctttcagtc tctttttata gcaagaaatc aatatccttt ttataaaaat   2160

tcatgtctgt atttcaggag caaactcttc aggctccttt tttataaact ggtgattttt   2220

cttttgtcta aaaaacacat gaagaaaatt tacc                               2254


<210>  10624
<211>  360
<212>  PRT
<213>  Homo sapiens

<400>  10624

Met Glu Leu Asp Phe Gly His Phe Asp Glu Arg Asp Lys Thr Ser Arg 
1               5                   10                  15


Asn Met Arg Gly Ser Arg Met Asn Gly Leu Pro Ser Pro Thr His Ser 
            20                  25                  30


Ala His Cys Ser Phe Tyr Arg Thr Arg Thr Leu Gln Ala Leu Ser Asn 
        35                  40                  45


Glu Lys Lys Ala Lys Lys Val Arg Phe Tyr Arg Asn Gly Asp Arg Tyr 
    50                  55                  60


Phe Lys Gly Ile Val Tyr Ala Val Ser Ser Asp Arg Phe Arg Ser Phe 
65                  70                  75                  80


Asp Ala Leu Leu Ala Asp Leu Thr Arg Ser Leu Ser Asp Asn Ile Asn 
                85                  90                  95


Leu Pro Gln Gly Val Arg Tyr Ile Tyr Thr Ile Asp Gly Ser Arg Lys 
            100                 105                 110


Ile Gly Ser Met Asp Glu Leu Glu Glu Gly Glu Ser Tyr Val Cys Ser 
        115                 120                 125


Ser Asp Asn Phe Phe Lys Lys Val Glu Tyr Thr Lys Asn Val Asn Pro 
    130                 135                 140


Asn Trp Ser Val Asn Val Lys Thr Ser Ala Asn Met Lys Ala Pro Gln 
145                 150                 155                 160


Ser Leu Ala Ser Ser Asn Ser Ala Gln Ala Arg Glu Asn Lys Asp Phe 
                165                 170                 175


Val Arg Pro Lys Leu Val Thr Ile Ile Arg Ser Gly Val Lys Pro Arg 
            180                 185                 190


Lys Ala Val Arg Val Leu Leu Asn Lys Lys Thr Ala His Ser Phe Glu 
        195                 200                 205


Gln Val Leu Thr Asp Ile Thr Glu Ala Ile Lys Leu Glu Thr Gly Val 
    210                 215                 220


Val Lys Lys Leu Tyr Thr Leu Asp Gly Lys Gln Val Thr Cys Leu His 
225                 230                 235                 240


Asp Phe Phe Gly Asp Asp Asp Val Phe Ile Ala Cys Gly Pro Glu Lys 
                245                 250                 255


Phe Arg Tyr Ala Gln Asp Asp Phe Ser Leu Asp Glu Asn Glu Cys Arg 
            260                 265                 270


Val Met Lys Gly Asn Pro Ser Ala Thr Ala Gly Pro Lys Ala Ser Pro 
        275                 280                 285


Thr Pro Gln Lys Thr Ser Ala Lys Ser Pro Gly Pro Met Arg Arg Ser 
    290                 295                 300


Lys Ser Pro Ala Asp Ser Ala Asn Gly Thr Ser Ser Ser Gln Leu Ser 
305                 310                 315                 320


Thr Pro Lys Ser Lys Gln Ser Pro Ile Ser Thr Pro Thr Ser Pro Gly 
                325                 330                 335


Ser Leu Arg Lys His Lys Asp Leu Tyr Leu Pro Leu Ser Leu Asp Asp 
            340                 345                 350


Ser Asp Ser Leu Gly Asp Ser Met 
        355                 360


<210>  10625
<211>  639
<212>  DNA
<213>  Homo sapiens

<400>  10625
cgggaagctg tgcaacatcg ccttggagcc acataaaaag ctatgcgaga ggccggagac     60

atcctgagag aatacaaact gtcagatggg aatgtcatcc acattgggga ccaactgtat    120

caagtgcccg aagttctttt tgcccctgac cagctgggaa tccacagccc gggactctca    180

ataatggcct ccagcaacat aatgaactgt gacactgaca tccagaagaa agtttttgca    240

gagattgtac tgtctggggg caccactctc ttttctgggc cagaggaaag gctcatgaaa    300

gaactggaac agctagcttc caaagggaac aatcggagaa actggttgtt ttacggaggc    360

tttgactgga atggtgtcct ttcctttaag gaatcaaact taacttacgg atccaacaaa    420

agccccttga gaaaactgga ctcatacttg tctacgcagt ctctgaacag agttcctgac    480

ctgtgagatc tggaacaaaa tctacaatat ctccaagaat gtataaaaca gaattgcagt    540

ctgaccactt caagaccact actctaggct ttttgggttt gttttctccc tggaccatgg    600

tcactcatat tggctcagaa taaacttctt tgaaatact                           639


<210>  10626
<211>  147
<212>  PRT
<213>  Homo sapiens

<400>  10626

Met Arg Glu Ala Gly Asp Ile Leu Arg Glu Tyr Lys Leu Ser Asp Gly 
1               5                   10                  15


Asn Val Ile His Ile Gly Asp Gln Leu Tyr Gln Val Pro Glu Val Leu 
            20                  25                  30


Phe Ala Pro Asp Gln Leu Gly Ile His Ser Pro Gly Leu Ser Ile Met 
        35                  40                  45


Ala Ser Ser Asn Ile Met Asn Cys Asp Thr Asp Ile Gln Lys Lys Val 
    50                  55                  60


Phe Ala Glu Ile Val Leu Ser Gly Gly Thr Thr Leu Phe Ser Gly Pro 
65                  70                  75                  80


Glu Glu Arg Leu Met Lys Glu Leu Glu Gln Leu Ala Ser Lys Gly Asn 
                85                  90                  95


Asn Arg Arg Asn Trp Leu Phe Tyr Gly Gly Phe Asp Trp Asn Gly Val 
            100                 105                 110


Leu Ser Phe Lys Glu Ser Asn Leu Thr Tyr Gly Ser Asn Lys Ser Pro 
        115                 120                 125


Leu Arg Lys Leu Asp Ser Tyr Leu Ser Thr Gln Ser Leu Asn Arg Val 
    130                 135                 140


Pro Asp Leu 
145


<210>  10627
<211>  1435
<212>  DNA
<213>  Homo sapiens

<400>  10627
ggagataaga ttcagaggtt gaggatgggg tgtcctggtg gactgaaggt agcctactag     60

ctgtacatgg gtgacaactt gaaacttcag aaccctgaag tttaaaaaat tctaaaggtg    120

cctgtcatct cagagagtga cgtaagtgtt ctttctttat ttgggggaag tccaggagaa    180

catattacag acatgtttaa tccacatgca ttagatgttc ctgctgtaat ttttgacaat    240

ggttcaggac tctgcaaagc aggcctgtct ggagagattg gaccccgcca tgtcatcagc    300

tccgtcttgg gacattgtaa attcaatgtg cctttagcaa gacttaatca gaagtacttc    360

gtggggcaag aagccctgta caagtatgag gccctacatt tgcactaccc cattgagcgt    420

ggactggtaa caggatggga tgacatggag aaactctgga aacatctctt tgagcgggag    480

cttggagtaa aacccagcca acagcctgta cttatgaccg agccctcttt gaatcctagg    540

gaaattcgag aaaagctagc agaaatgatg tttgagacct tcagtgtgcc tggtttctac    600

ctgtctaatc atgcggtggc agcgctctat gcctctgcct gtgtcacagg cctggtggtg    660

gacagtggag atggggtcac ttgcactgtc cccatctttg agggttactc cctgcctcac    720

gcagtcacca aactctgtat ggcagggagg gacatcacag agcacctcac ccggctcctc    780

tttgctagcg ggtttaactt cccttgcata ctcaacaagg ccgtggtaaa taacatcaaa    840

gagaagttgt gctacatcgc cttggagcca gagaaagagc tacgcaagag ccggggagag    900

gtcctgggag catacagact gccagatgga catgtcatcc actttgggga tgagctgtac    960

caagtgcccg aggttctttt tgcacctgac cagctgggca tccacagccc aggactctca   1020

aaaatggtct ccagcagcat catgaagtgt gacactgaca tccagaataa actttatgca   1080

gacattgtac tctccggggg caccactctc ctccctgggc tggaggaaag gctcatgaag   1140

gaagtggaac agctggcttc caaaggtact cccatcaaga tcacagcttc tcctgataga   1200

tgcttctctg catggattgg tgcatccatc atgacctcta tgagcagttt caagcagatg   1260

tgggtcacct cggcagactt caaggagtat gggacatctg tggttcaaag aaggtgcttt   1320

taaagatcct tgagcagagg agacatcttg aagtgtcaga ttacaggagt accagtggga   1380

gatggcattt tcttctgggc ttcagcatga tgttcaataa aagttttgcc atttc        1435


<210>  10628
<211>  376
<212>  PRT
<213>  Homo sapiens

<400>  10628

Met Phe Asn Pro His Ala Leu Asp Val Pro Ala Val Ile Phe Asp Asn 
1               5                   10                  15


Gly Ser Gly Leu Cys Lys Ala Gly Leu Ser Gly Glu Ile Gly Pro Arg 
            20                  25                  30


His Val Ile Ser Ser Val Leu Gly His Cys Lys Phe Asn Val Pro Leu 
        35                  40                  45


Ala Arg Leu Asn Gln Lys Tyr Phe Val Gly Gln Glu Ala Leu Tyr Lys 
    50                  55                  60


Tyr Glu Ala Leu His Leu His Tyr Pro Ile Glu Arg Gly Leu Val Thr 
65                  70                  75                  80


Gly Trp Asp Asp Met Glu Lys Leu Trp Lys His Leu Phe Glu Arg Glu 
                85                  90                  95


Leu Gly Val Lys Pro Ser Gln Gln Pro Val Leu Met Thr Glu Pro Ser 
            100                 105                 110


Leu Asn Pro Arg Glu Ile Arg Glu Lys Leu Ala Glu Met Met Phe Glu 
        115                 120                 125


Thr Phe Ser Val Pro Gly Phe Tyr Leu Ser Asn His Ala Val Ala Ala 
    130                 135                 140


Leu Tyr Ala Ser Ala Cys Val Thr Gly Leu Val Val Asp Ser Gly Asp 
145                 150                 155                 160


Gly Val Thr Cys Thr Val Pro Ile Phe Glu Gly Tyr Ser Leu Pro His 
                165                 170                 175


Ala Val Thr Lys Leu Cys Met Ala Gly Arg Asp Ile Thr Glu His Leu 
            180                 185                 190


Thr Arg Leu Leu Phe Ala Ser Gly Phe Asn Phe Pro Cys Ile Leu Asn 
        195                 200                 205


Lys Ala Val Val Asn Asn Ile Lys Glu Lys Leu Cys Tyr Ile Ala Leu 
    210                 215                 220


Glu Pro Glu Lys Glu Leu Arg Lys Ser Arg Gly Glu Val Leu Gly Ala 
225                 230                 235                 240


Tyr Arg Leu Pro Asp Gly His Val Ile His Phe Gly Asp Glu Leu Tyr 
                245                 250                 255


Gln Val Pro Glu Val Leu Phe Ala Pro Asp Gln Leu Gly Ile His Ser 
            260                 265                 270


Pro Gly Leu Ser Lys Met Val Ser Ser Ser Ile Met Lys Cys Asp Thr 
        275                 280                 285


Asp Ile Gln Asn Lys Leu Tyr Ala Asp Ile Val Leu Ser Gly Gly Thr 
    290                 295                 300


Thr Leu Leu Pro Gly Leu Glu Glu Arg Leu Met Lys Glu Val Glu Gln 
305                 310                 315                 320


Leu Ala Ser Lys Gly Thr Pro Ile Lys Ile Thr Ala Ser Pro Asp Arg 
                325                 330                 335


Cys Phe Ser Ala Trp Ile Gly Ala Ser Ile Met Thr Ser Met Ser Ser 
            340                 345                 350


Phe Lys Gln Met Trp Val Thr Ser Ala Asp Phe Lys Glu Tyr Gly Thr 
        355                 360                 365


Ser Val Val Gln Arg Arg Cys Phe 
    370                 375


<210>  10629
<211>  1056
<212>  DNA
<213>  Homo sapiens

<400>  10629
tatatcagac catcagaagg atttgtataa agagtgactc tcctatgaag gtaaaggcca     60

cccctcttca gttccagtga ctgagataca tttttccaat cctgggggca aatacagaca    120

cagcaagttc cttcttccct ttggaaattt ggcagaaatc ctcactggac ggcttcctgt    180

ttcctgtggt tcattatctg attggctgca gggatgaaag tttttaagtt cataggactg    240

atgatcctcc tcacctctgc gttttcagcc ggttcaggac aaagtccaat gactgtgctg    300

tgctccatag actggttcat ggtcacagtg caccccttca tgctaaacaa cgatgtgtgt    360

gtacactttc atgaactaca cttgggcctg ggttgccccc caaaccatgt tcagccacac    420

gcctaccagt tcacctaccg tgttactgaa tgtggcatca gggccaaagc tgtctctcag    480

gacatggtta tctacagcac tgagatacac tactcttcta agggcacgcc atctaagttt    540

gtgatcccag tgtcatgtgc tgccccccaa aagtccccat ggctcaccaa gccctgctcc    600

atgagagtag ccagcaagag cagggccaca gcccagaagg atgagaaatg ctacgaggtg    660

ttcagcttgt cacagtccag tcaaaggccc aactgcgatt gtccaccttg tgtcttcagt    720

gaagaagagc atacccaggt cccttgtcac caagcagggg ctcaggaggc tcaacctctg    780

cagccatctc actttcttga tatttctgag gattggtctc ttcacacaga tgatatgatt    840

gggtccatgt gatcctcagg tttggggtct cctgaagatg ctatttctag aattagtata    900

tagtgtacaa atgtctgaca aataagtgct cttgtgaccc tcatgtgagc acttttgaga    960

aagagaaacc tatagcaact tcatgaatta agcctttttc tatattttta tattcatgtg   1020

taaacaaaaa ataaaataaa attctgatcg cataaa                             1056


<210>  10630
<211>  212
<212>  PRT
<213>  Homo sapiens

<400>  10630

Met Lys Val Phe Lys Phe Ile Gly Leu Met Ile Leu Leu Thr Ser Ala 
1               5                   10                  15


Phe Ser Ala Gly Ser Gly Gln Ser Pro Met Thr Val Leu Cys Ser Ile 
            20                  25                  30


Asp Trp Phe Met Val Thr Val His Pro Phe Met Leu Asn Asn Asp Val 
        35                  40                  45


Cys Val His Phe His Glu Leu His Leu Gly Leu Gly Cys Pro Pro Asn 
    50                  55                  60


His Val Gln Pro His Ala Tyr Gln Phe Thr Tyr Arg Val Thr Glu Cys 
65                  70                  75                  80


Gly Ile Arg Ala Lys Ala Val Ser Gln Asp Met Val Ile Tyr Ser Thr 
                85                  90                  95


Glu Ile His Tyr Ser Ser Lys Gly Thr Pro Ser Lys Phe Val Ile Pro 
            100                 105                 110


Val Ser Cys Ala Ala Pro Gln Lys Ser Pro Trp Leu Thr Lys Pro Cys 
        115                 120                 125


Ser Met Arg Val Ala Ser Lys Ser Arg Ala Thr Ala Gln Lys Asp Glu 
    130                 135                 140


Lys Cys Tyr Glu Val Phe Ser Leu Ser Gln Ser Ser Gln Arg Pro Asn 
145                 150                 155                 160


Cys Asp Cys Pro Pro Cys Val Phe Ser Glu Glu Glu His Thr Gln Val 
                165                 170                 175


Pro Cys His Gln Ala Gly Ala Gln Glu Ala Gln Pro Leu Gln Pro Ser 
            180                 185                 190


His Phe Leu Asp Ile Ser Glu Asp Trp Ser Leu His Thr Asp Asp Met 
        195                 200                 205


Ile Gly Ser Met 
    210


<210>  10631
<211>  1129
<212>  DNA
<213>  Homo sapiens

<400>  10631
atatatcaga ccatcagaag gatttgtata aagagtgact ctcctatgaa ggtaaaggcc     60

acccctcttc agttccagtg actgagatac atttttccaa tcctgggggc aaatacagac    120

acagcaagtt ccttcttccc tttggaaatt tggcagctgc cttcaccagt gagcacaaag    180

ccacatttca aaggaaactg acaaattatc cccagctgcc agaagaagaa atcctcactg    240

gacggcttcc tgtttcctgt ggttcattat ctgattggct gcagggatga aagtttttaa    300

gttcatagga ctgatgatcc tcctcacctc tgcgttttca gccggttcag gacaaagtcc    360

aatgactgtg ctgtgctcca tagactggtt catggtcaca gtgcacccct tcatgctaaa    420

caacgatgtg tgtgtacact ttcatgaact acacttgggc ctgggttgcc ccccaaacca    480

tgttcagcca cacgcctacc agttcaccta ccgtgttact gaatgtggca tcagggccaa    540

agctgtctct caggacatgg ttatctacag cactgagata cactactctt ctaagggcac    600

gccatctaag tttgtgatcc cagtgtcatg tgctgccccc caaaagtccc catggctcac    660

caagccctgc tccatgagag tagccagcaa gagcagggcc acagcccaga aggatgagaa    720

atgctacgag gtgttcagct tgtcacagtc cagtcaaagg cccaactgcg attgtccacc    780

ttgtgtcttc agtgaagaag agcataccca ggtcccttgt caccaagcag gggctcagga    840

ggctcaacct ctgcagccat ctcactttct tgatatttct gaggattggt ctcttcacac    900

agatgatatg attgggtcca tgtgatcctc aggtttgggg tctcctgaag atgctatttc    960

tagaattagt atatagtgta caaatgtctg acaaataagt gctcttgtga ccctcatgtg   1020

agcacttttg agaaagagaa acctatagca acttcatgaa ttaagccttt ttctatattt   1080

ttatattcat gtgtaaacaa aaaataaaat aaaattctga tcgcataaa               1129


<210>  10632
<211>  212
<212>  PRT
<213>  Homo sapiens

<400>  10632

Met Lys Val Phe Lys Phe Ile Gly Leu Met Ile Leu Leu Thr Ser Ala 
1               5                   10                  15


Phe Ser Ala Gly Ser Gly Gln Ser Pro Met Thr Val Leu Cys Ser Ile 
            20                  25                  30


Asp Trp Phe Met Val Thr Val His Pro Phe Met Leu Asn Asn Asp Val 
        35                  40                  45


Cys Val His Phe His Glu Leu His Leu Gly Leu Gly Cys Pro Pro Asn 
    50                  55                  60


His Val Gln Pro His Ala Tyr Gln Phe Thr Tyr Arg Val Thr Glu Cys 
65                  70                  75                  80


Gly Ile Arg Ala Lys Ala Val Ser Gln Asp Met Val Ile Tyr Ser Thr 
                85                  90                  95


Glu Ile His Tyr Ser Ser Lys Gly Thr Pro Ser Lys Phe Val Ile Pro 
            100                 105                 110


Val Ser Cys Ala Ala Pro Gln Lys Ser Pro Trp Leu Thr Lys Pro Cys 
        115                 120                 125


Ser Met Arg Val Ala Ser Lys Ser Arg Ala Thr Ala Gln Lys Asp Glu 
    130                 135                 140


Lys Cys Tyr Glu Val Phe Ser Leu Ser Gln Ser Ser Gln Arg Pro Asn 
145                 150                 155                 160


Cys Asp Cys Pro Pro Cys Val Phe Ser Glu Glu Glu His Thr Gln Val 
                165                 170                 175


Pro Cys His Gln Ala Gly Ala Gln Glu Ala Gln Pro Leu Gln Pro Ser 
            180                 185                 190


His Phe Leu Asp Ile Ser Glu Asp Trp Ser Leu His Thr Asp Asp Met 
        195                 200                 205


Ile Gly Ser Met 
    210


<210>  10633
<211>  949
<212>  DNA
<213>  Homo sapiens

<400>  10633
cttctctctc ctgccaccac atgaagaaag acatgtttgc ttccccttcc gccatgagtg     60

taagtttcct gaggcctccc cagccatgtg gaactggaca tggtcaccca ggctggagca    120

cggtggtgca atcacagctc actgcagcct caaacttcaa aggatcctca catctcagcc    180

tgctgagtag ggcctctcag cttgtggcat gattcactga aatacatcaa acatgacaga    240

agatgcaagc atttggaaac ttacatcagc catcatcaaa ttaaaaagct aaaaagtgct    300

atcagctggc ttgctcatca ttgagtgacc tgaagtgatg gatgatggag aggaggttgc    360

tgtgagggta gaggtggctc agtaccctgc aggagcaatg caaagagaga ctgtgcccaa    420

gaccatctcc ccggggggga tgggtggcat tcctgccttc cttccaccaa caaatgttga    480

ctgtgccatg cactgggatg acagagatga ctcagatgtg cccttgtcct caatgtgttc    540

atggttggat gaggagaaca ccagtcttac tctagtgact gaaggctaag acaaagactc    600

cagcctcaaa cttgaggaag gaagttcatg tttcttcctg ggttggccaa tagaaagtgg    660

tatttgtggc cgggcatggt ggctcacgct tgtaatccca gcactttggg aagccgaggc    720

gggtggatca cgaggtcaag agatcaagac catcctggcc aatatggtga aaccctgtct    780

ctactagaga tacaaaaaaa ttagctgggt gtggtggcat gcacctgtag tcccagctac    840

tcaggaggct gaggcaggag aatcgcttga tcctgggagg cggaggctgc agtgagccaa    900

aatcgcacca ctgcactcca gcccgggtga cagagtgaga ctccatctc                949


<210>  10634
<211>  63
<212>  PRT
<213>  Homo sapiens

<400>  10634

Met Lys Lys Asp Met Phe Ala Ser Pro Ser Ala Met Ser Val Ser Phe 
1               5                   10                  15


Leu Arg Pro Pro Gln Pro Cys Gly Thr Gly His Gly His Pro Gly Trp 
            20                  25                  30


Ser Thr Val Val Gln Ser Gln Leu Thr Ala Ala Ser Asn Phe Lys Gly 
        35                  40                  45


Ser Ser His Leu Ser Leu Leu Ser Arg Ala Ser Gln Leu Val Ala 
    50                  55                  60


<210>  10635
<211>  98
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10635
cauauuaggu uaaugcaaaa guaaucgcgg uuugugccag augacgauuu gaauuaauaa     60

auucauuugg uauaaaccgc gauuauuuuu gcaucaac                             98


<210>  10636
<211>  72
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10636
agauacugua aacauccuac acucucagcu guggaaagua agaaagcugg gagaaggcug     60

uuuacucuuu cu                                                         72


<210>  10637
<211>  97
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10637
uagccaguca gaaaugagcu uauucauaaa agugcaguau ggugaaguca aucuguaauu     60

uuauguauaa gcuagucucu gauugaaaca ugcagca                              97


<210>  10638
<211>  97
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10638
gauugaugcu guugguuugg ugcaaaagua auugcagugc uucccauuua aaaguaaugg     60

cacacacugc aauuacuuuu gcuccaacuu aauacuu                              97


<210>  10639
<211>  76
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10639
gagggggaag acgggaggaa agaagggagu gguuccauca cgccuccuca cuccucuccu     60

cccgucuucu ccucuc                                                     76


<210>  10640
<211>  90
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10640
ggaggcccgu uucucucuuu gguuaucuag cuguaugagu gccacagagc cgucauaaag     60

cuagauaacc gaaaguagaa augauucuca                                      90


<210>  10641
<211>  79
<212>  RNA
<213>  Homo sapiens


<220>  
<221>  misc_RNA
<223>  miRNA sequence.

<400>  10641
agccucguca ggcucagucc ccucccgaua aaccccuaaa uagggacuuu cccggggggu     60

gacccuggcu uuuuuggcg                                                  79


<210>  10642
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10642
gtttatcttc rgacaacagg c                                               21


<210>  10643
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10643
ccctgggcat wcggagatgt a                                               21


<210>  10644
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10644
ccgggcgggc rttgccgacg g                                               21


<210>  10645
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10645
cctgcaatta yaggtcagtc c                                               21


<210>  10646
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10646
ggctgccctc rttgagccat t                                               21


<210>  10647
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10647
cccttagtgc rtgctgaata t                                               21


<210>  10648
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10648
tcgtccatgt rgaggaagag g                                               21


<210>  10649
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10649
gctctcacag yagttcctat t                                               21


<210>  10650
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10650
gattgagatc yggaccgatt c                                               21


<210>  10651
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10651
agactattat yatctttagc a                                               21


<210>  10652
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10652
cccaaagcaa watcaagcag g                                               21


<210>  10653
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10653
aggaggagat ktggggtctc t                                               21


<210>  10654
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10654
caatgtgaac sggaaaggaa a                                               21


<210>  10655
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10655
gaattacact kagatttttc t                                               21


<210>  10656
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10656
tcatgatggg scctgtttca c                                               21


<210>  10657
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10657
cgtttgcggg saagtccctc t                                               21


<210>  10658
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10658
atacacaata ygagctatgt g                                               21


<210>  10659
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10659
agcattagct yggtcaggtt t                                               21


<210>  10660
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10660
gcctggcctt ygagagactc t                                               21


<210>  10661
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10661
gtgaagagag rgagcacacg g                                               21


<210>  10662
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10662
ggttgaggct ragcaaaaca g                                               21


<210>  10663
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10663
ggtgccaggg wctttcctac a                                               21


<210>  10664
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10664
aaccaaggcc rtgtagtaga a                                               21


<210>  10665
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10665
actcaaatct yctgtcattg g                                               21


<210>  10666
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10666
tttttaaaaa sacggcctgg a                                               21


<210>  10667
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10667
cttgtgtttt satgtgatca c                                               21


<210>  10668
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10668
tccgctacct kgcagtgttt g                                               21


<210>  10669
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10669
aatacttcta yagtagagca a                                               21


<210>  10670
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10670
gtttattttc ytgtcaaagt t                                               21


<210>  10671
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10671
ttataacagc rgttcatata t                                               21


<210>  10672
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10672
gaagactaaa rtgtttgaaa t                                               21


<210>  10673
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10673
ctgcagccta sagagcaagc c                                               21


<210>  10674
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10674
tcaatttaac rgcactgcaa c                                               21


<210>  10675
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10675
tgtaacgtgt rtaatacctt g                                               21


<210>  10676
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10676
gctggaagac wggaggctca t                                               21


<210>  10677
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10677
gttactcaga rcacagctta a                                               21


<210>  10678
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10678
agaactgtgg rttatgtgtc c                                               21


<210>  10679
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10679
ctttaaaaag ytgttctaag g                                               21


<210>  10680
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10680
gttcagtgaa yattaatttg c                                               21


<210>  10681
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10681
tctcaagaga stacagtcca t                                               21


<210>  10682
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10682
taccagtgac rtaggaaaaa g                                               21


<210>  10683
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10683
tgtgcagata wccctgttca a                                               21


<210>  10684
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10684
aagtagagca racagacatt a                                               21


<210>  10685
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10685
aatacaatac mtagttcagt a                                               21


<210>  10686
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10686
aagccaaaga ygactttacg a                                               21


<210>  10687
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10687
gggttaaaga mtttgctgtt g                                               21


<210>  10688
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10688
caattgcgct rttacaacct a                                               21


<210>  10689
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10689
cttagttgaa raacacctcc c                                               21


<210>  10690
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10690
cagtttatag wcacattcaa a                                               21


<210>  10691
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10691
ctgcaggaac wgttgctgtc a                                               21


<210>  10692
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10692
accaccaaga mgaggacata g                                               21


<210>  10693
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10693
atgttcactg rgaagcctcc t                                               21


<210>  10694
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10694
tagctcatgg ytcttcactc a                                               21


<210>  10695
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10695
ttcaaaatgc rtaaccacac c                                               21


<210>  10696
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10696
tggaaacctc rccaacgccc c                                               21


<210>  10697
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10697
gcctgactaa yggctgctta g                                               21


<210>  10698
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10698
taccgctgag rgtctccttc c                                               21


<210>  10699
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10699
gtgtcccttc raccagaaca a                                               21


<210>  10700
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10700
tccaaagacc rtatccccaa a                                               21


<210>  10701
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10701
atttaaccca ytcctgatat a                                               21


<210>  10702
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10702
aaaaaagact stagaactgc a                                               21


<210>  10703
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10703
ttccagtttt ygaacatacc t                                               21


<210>  10704
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10704
agctgacagt yggttgatcc c                                               21


<210>  10705
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10705
ttatccagct stttattaga a                                               21


<210>  10706
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10706
caggttactg yggtgtgtgg a                                               21


<210>  10707
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10707
gacctatcac rgaccaagga c                                               21


<210>  10708
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10708
aagagaggga raggtagttg c                                               21


<210>  10709
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10709
acatgcaagg sgctatgatc a                                               21


<210>  10710
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10710
tgcttgtacc yagagctctg a                                               21


<210>  10711
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10711
agtgcaaggt kgattaacac a                                               21


<210>  10712
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10712
tattctaggc maacagaata g                                               21


<210>  10713
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10713
tgaaaagcac rggatgagac a                                               21


<210>  10714
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10714
gagtcgatac raagggtgag a                                               21


<210>  10715
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10715
ttgccagcac rataactgag a                                               21


<210>  10716
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10716
gaaagcatga sattgttact g                                               21


<210>  10717
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10717
gtggtggaga rcagcatcac a                                               21


<210>  10718
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10718
aagagactta yatagtttag c                                               21


<210>  10719
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10719
tttgcatttg ktcttcagga c                                               21


<210>  10720
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10720
aaggccttaa rgaacccact t                                               21


<210>  10721
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10721
tgctccagac mgtagaaatt g                                               21


<210>  10722
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10722
ctaaggtcat rcatgattta a                                               21


<210>  10723
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10723
aagaacaaac mgtctagaga a                                               21


<210>  10724
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10724
actctgtatt ytctaggaaa g                                               21


<210>  10725
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10725
gtgatgaact ygtcctctaa g                                               21


<210>  10726
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10726
tgtaggtgat kgtttcttcc t                                               21


<210>  10727
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10727
atctaaatgg ygaaagaaag a                                               21


<210>  10728
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10728
tcatgtgaag stacatattg a                                               21


<210>  10729
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10729
ctcatccgct yctgggagat t                                               21


<210>  10730
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10730
ttaacacaca kataagcagg g                                               21


<210>  10731
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10731
aaagaaaata mgaataatgg a                                               21


<210>  10732
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10732
tcagaaggct rgtatatgat t                                               21


<210>  10733
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10733
atttttgaga rgctcttctg c                                               21


<210>  10734
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10734
ctatggtcta ragttccatc c                                               21


<210>  10735
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10735
aaaaacccta stgttatatt a                                               21


<210>  10736
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10736
gggagagttg ycacaggagc t                                               21


<210>  10737
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10737
tattgaccca ycaaccctga a                                               21


<210>  10738
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10738
tcagtagggg kccctgaaag t                                               21


<210>  10739
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10739
attcagaacc rtatgcttct a                                               21


<210>  10740
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10740
tgcttattag ygtagcatga a                                               21


<210>  10741
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10741
aaaatttttg rgtgtgaaaa c                                               21


<210>  10742
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10742
ctcaaaaaaa wttaaactcc c                                               21


<210>  10743
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10743
ttcaccattg mtaggacttg g                                               21


<210>  10744
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10744
cttaagttca yagcactgca a                                               21


<210>  10745
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10745
ttgtcaaaag sgtctatgga a                                               21


<210>  10746
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10746
ttttagaatg ytttttaaag a                                               21


<210>  10747
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10747
ttttctagcc raagttattt t                                               21


<210>  10748
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10748
ttaagacaaa kttaagtccc c                                               21


<210>  10749
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10749
ttgatttttg wcattagtaa c                                               21


<210>  10750
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10750
ctgtggtagg raccaaatcc a                                               21


<210>  10751
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10751
ctagaaagtg rtgtaacctc a                                               21


<210>  10752
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10752
caatggaagc rccaaatgac t                                               21


<210>  10753
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10753
tttaaaccaa mtcatgacct g                                               21


<210>  10754
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10754
catgtggttt yatattagca g                                               21


<210>  10755
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10755
tacttctgtc macatcaaga a                                               21


<210>  10756
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10756
gttctggttg ygtggattgg a                                               21


<210>  10757
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10757
atctataaga yactccttag c                                               21


<210>  10758
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10758
tacccaagac kataattggc a                                               21


<210>  10759
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10759
gataatcccc ygtgtaatta a                                               21


<210>  10760
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10760
agaagctggc rtttcttaga a                                               21


<210>  10761
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10761
gttacaggtc maaaagcctt g                                               21


<210>  10762
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10762
ccacacatag ytaaaaagga a                                               21


<210>  10763
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10763
gacaaggtcc ygaatggtgt c                                               21


<210>  10764
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10764
agtaagaatg matatagtcc a                                               21


<210>  10765
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10765
aaatgctaaa rtatcagttc t                                               21


<210>  10766
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10766
tcaatggagc ytcaggttca t                                               21


<210>  10767
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10767
cagagtattc kgataaactg a                                               21


<210>  10768
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10768
tctaaacaca raaatagtca g                                               21


<210>  10769
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10769
taaaactaaa rgagatgaac a                                               21


<210>  10770
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10770
ctgctgaagc yactgaatta c                                               21


<210>  10771
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10771
ctacagtgac ytctattctt g                                               21


<210>  10772
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10772
ttcttactgc rggccacaga a                                               21


<210>  10773
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10773
cccttatttg ycaccaaaca g                                               21


<210>  10774
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10774
gactcctttg yattttccac a                                               21


<210>  10775
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10775
tatattccat yctttaacat t                                               21


<210>  10776
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10776
ttttcttgcc yaatgctgca a                                               21


<210>  10777
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10777
tccatactga sagatcttcc c                                               21


<210>  10778
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10778
tacaagtagt waatgttaaa g                                               21


<210>  10779
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10779
tgcagtagct yatatagtat t                                               21


<210>  10780
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10780
tgtgcttaat rtgtcgtgca c                                               21


<210>  10781
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10781
ttgatttctt ygtggaccat c                                               21


<210>  10782
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10782
gttgtttatg ratggcctta t                                               21


<210>  10783
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10783
tctgcttatc rttttgcttc a                                               21


<210>  10784
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10784
ttgcattggt rgataaatgc a                                               21


<210>  10785
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10785
gaaaactgat kgcgattact a                                               21


<210>  10786
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10786
aatgactgaa sataagtccc c                                               21


<210>  10787
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10787
ctcctttgcc rtatatcaag t                                               21


<210>  10788
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10788
acaagaggct rcagctacca a                                               21


<210>  10789
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10789
ggtattattc rcactagaac t                                               21


<210>  10790
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10790
tatggagctt wcaggagtgg c                                               21


<210>  10791
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10791
tgcgtcttag wattccaaaa t                                               21


<210>  10792
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10792
tatactgaga kaagcagaga t                                               21


<210>  10793
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10793
ttttcactga ytgctgtata a                                               21


<210>  10794
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10794
attcaccatc rcttatgatg g                                               21


<210>  10795
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10795
cttctaacag ytccaaagtt t                                               21


<210>  10796
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10796
tctaaatgag rcatcttggg a                                               21


<210>  10797
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10797
acttccattt rtacctgatt t                                               21


<210>  10798
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10798
cttattaaat stccttgccc t                                               21


<210>  10799
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10799
cttggaggga mctcagactg t                                               21


<210>  10800
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10800
gcctaagtgt yagaaatctg t                                               21


<210>  10801
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10801
ggacacttaa yctcactttg c                                               21


<210>  10802
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10802
cagaaactta ytttgtgctt c                                               21


<210>  10803
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10803
attattttac rgtcaaaaga t                                               21


<210>  10804
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10804
aaaaaagcgc rggaggaggt t                                               21


<210>  10805
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10805
aaggtctgtt kttatatggt c                                               21


<210>  10806
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10806
tagccaatgc rgttagaagc a                                               21


<210>  10807
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10807
gaataggcag mcagtttttc t                                               21


<210>  10808
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10808
aaggtaacaa rcagagtgca a                                               21


<210>  10809
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10809
atgagaagac rgattttaat t                                               21


<210>  10810
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10810
ccctatcctc yctgtggcta t                                               21


<210>  10811
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10811
acttttctaa yttatcctct t                                               21


<210>  10812
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10812
ctgtctatag ygttgagtca t                                               21


<210>  10813
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10813
gtgaacatac rcacacatgt g                                               21


<210>  10814
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10814
gtcatgagtc rtgtgtagta a                                               21


<210>  10815
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10815
aactacaata mcccaggttt c                                               21


<210>  10816
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10816
ggtgatcata ygcaaataac t                                               21


<210>  10817
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10817
agtcaggtga ygcagggttt t                                               21


<210>  10818
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10818
catttcctgc ycttaacagg c                                               21


<210>  10819
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10819
agtactacaa yaaagaaact g                                               21


<210>  10820
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10820
cccatttatt stgctgaaac a                                               21


<210>  10821
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10821
gctaagcttt rcgggacagt g                                               21


<210>  10822
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10822
tgagagaaaa kgaatgggtg g                                               21


<210>  10823
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10823
agaagcatat rttgagggac t                                               21


<210>  10824
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10824
gagagtaaag ytgactaaca t                                               21


<210>  10825
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10825
aagcttcagc rcaaaacatt t                                               21


<210>  10826
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10826
tatgatatta rttccccaga c                                               21


<210>  10827
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10827
cataaaaatt yaagtagctt t                                               21


<210>  10828
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10828
ttccatacag yactgagagg g                                               21


<210>  10829
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10829
gaaggcagca rcagagagca t                                               21


<210>  10830
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10830
tatgtcacca ktagatgtgt c                                               21


<210>  10831
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10831
tggcttgttg maacattaca a                                               21


<210>  10832
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10832
tggaccgact rgctgaatgg g                                               21


<210>  10833
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10833
aagggcagca ragtgaagtg c                                               21


<210>  10834
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10834
aagtgagaga ygttcttagt a                                               21


<210>  10835
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10835
ttgccttgga wgacatcctc t                                               21


<210>  10836
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10836
acatcacttc yggtataaag c                                               21


<210>  10837
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10837
aaaggatacc rtcattccat t                                               21


<210>  10838
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10838
attgggaaag rgcaggagaa a                                               21


<210>  10839
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10839
atgaaaattc ktttggctaa g                                               21


<210>  10840
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10840
acacatgaaa ygcccacaga c                                               21


<210>  10841
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10841
gggatgctgg ygggttagca c                                               21


<210>  10842
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10842
ttttttgttt mtcctccttg a                                               21


<210>  10843
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10843
aactgatggg ycgagcctgc t                                               21


<210>  10844
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10844
tgccagtcta rcctactttg g                                               21


<210>  10845
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10845
ataagcactc rtttctgctg g                                               21


<210>  10846
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10846
actaaggacg rctagactga t                                               21


<210>  10847
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10847
ctgatataca kattgtactt a                                               21


<210>  10848
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10848
actttgcttc yaattacagc t                                               21


<210>  10849
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10849
ttggtagtcc rgtaagaaga t                                               21


<210>  10850
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10850
cttagtctgc yatgattatc c                                               21


<210>  10851
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10851
ctagatttac rtagttcggc t                                               21


<210>  10852
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10852
tattaattaa ragagaaatc t                                               21


<210>  10853
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10853
aggaatgaga yaagaattgt g                                               21


<210>  10854
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10854
gagagaacca wtctccatga g                                               21


<210>  10855
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10855
ttgtttcctg yaccagcgca g                                               21


<210>  10856
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10856
acttcataca rcatatagct t                                               21


<210>  10857
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10857
acaaactata waaatggaat g                                               21


<210>  10858
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10858
aggatatact rtttacattg t                                               21


<210>  10859
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10859
ggccaatgaa ractcccatg c                                               21


<210>  10860
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10860
ctgattcctc ratccctttg g                                               21


<210>  10861
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10861
tgtgtataat rtcaactatt a                                               21


<210>  10862
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10862
gacacaaata ygcaagaaag a                                               21


<210>  10863
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10863
gaggcagctt rctggggacc t                                               21


<210>  10864
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10864
aaaagtgtga rgctgttcat c                                               21


<210>  10865
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10865
ctggcaggac ytgcagcatt t                                               21


<210>  10866
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10866
ttcatgtcag rggtatcagt c                                               21


<210>  10867
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10867
tgtatagact rtaccccaaa a                                               21


<210>  10868
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10868
ggaaaagctc ytatcatttg c                                               21


<210>  10869
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10869
tctcctgcag mtgcggatac t                                               21


<210>  10870
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10870
tcaaaaagaa rggctgctta g                                               21


<210>  10871
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10871
aaagtggtag kaaaacaagt t                                               21


<210>  10872
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10872
ttaaacatta mattcagttc a                                               21


<210>  10873
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10873
ccagactgaa yttggattaa a                                               21


<210>  10874
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10874
aggagtgcca raatgctcat t                                               21


<210>  10875
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10875
catgatcagc raagttttta a                                               21


<210>  10876
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10876
ccaagcctgc wcatttctga t                                               21


<210>  10877
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10877
gtgcatttgc wttctgtcca a                                               21


<210>  10878
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10878
tctcatgctc yctcaccgtg a                                               21


<210>  10879
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10879
ctgctaaccc rtacattcat t                                               21


<210>  10880
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10880
gaaacacttc rtcatattat a                                               21


<210>  10881
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10881
tgaggaggca wgattttgca a                                               21


<210>  10882
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10882
tataaaagtt scatgtacct a                                               21


<210>  10883
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10883
gaatactgtg kaagtgcaac c                                               21


<210>  10884
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10884
tatacatggc rcagcaaatg a                                               21


<210>  10885
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10885
gaacatggta rgagcagtgt t                                               21


<210>  10886
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10886
tttttattgt saattgatga t                                               21


<210>  10887
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10887
tgccagtttt rttttaacac a                                               21


<210>  10888
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10888
aaaataataa ygatgatttg c                                               21


<210>  10889
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10889
aagcattcct yactgcccag t                                               21


<210>  10890
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10890
caggtaaatt matcacgtgc a                                               21


<210>  10891
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10891
gagggtagtt rgtaattgcc a                                               21


<210>  10892
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10892
attgaattgt yccattgcaa t                                               21


<210>  10893
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10893
tgactgccaa mtcttatgct c                                               21


<210>  10894
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10894
cctgtgggga kagtgagttg t                                               21


<210>  10895
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10895
atatttacct rttacttcaa t                                               21


<210>  10896
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10896
tttcattcaa yagtacaatc t                                               21


<210>  10897
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10897
gattgtgtat ygtgcttcta g                                               21


<210>  10898
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10898
cagctatagc rtctcatctt t                                               21


<210>  10899
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10899
ctcacactta mtggtgtaaa a                                               21


<210>  10900
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10900
agtggtaatc rtctctgttt c                                               21


<210>  10901
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10901
agagaaaagg yggctgcttt t                                               21


<210>  10902
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10902
gaagcatgtc staatgagag a                                               21


<210>  10903
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10903
tatattctct mtcctcccac a                                               21


<210>  10904
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10904
cttagatgtc rtaaatgttt t                                               21


<210>  10905
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10905
tgcaagaatt yagaccatga t                                               21


<210>  10906
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10906
aatgcaggga sttactcaga g                                               21


<210>  10907
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10907
cctataacta yaggtcttta t                                               21


<210>  10908
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10908
catttaagct mtaagtcagt t                                               21


<210>  10909
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10909
taaaattcag rtgaatgaga c                                               21


<210>  10910
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10910
taacatcatt ytgacagaac t                                               21


<210>  10911
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10911
tttgctcaaa yccctagaga t                                               21


<210>  10912
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10912
ggaacttcct kctgcaaaac a                                               21


<210>  10913
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10913
acaagactat matgaaggac a                                               21


<210>  10914
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10914
gattacatga wtgtggattt c                                               21


<210>  10915
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10915
acagggaaaa sccagatttg g                                               21


<210>  10916
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10916
atgttgtatg yttatagtac a                                               21


<210>  10917
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10917
agcttaagta sggtttatac a                                               21


<210>  10918
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10918
gatctatgag rgttatagaa a                                               21


<210>  10919
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10919
agtcaagatg kcaaggaggc t                                               21


<210>  10920
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10920
tcagttctag ragctgccta t                                               21


<210>  10921
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10921
ttgttttctt yctaaaggcc t                                               21


<210>  10922
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10922
gaacatcctt ktaacttcag a                                               21


<210>  10923
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10923
gtccaatctt rttttacata t                                               21


<210>  10924
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10924
caatagttcc yattttccac a                                               21


<210>  10925
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10925
tccagtccct kccctataac c                                               21


<210>  10926
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10926
gccaaggaca rttatacaga a                                               21


<210>  10927
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10927
ctctagtttt rtcccatatg g                                               21


<210>  10928
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10928
taattgatgg ytttaaaaaa t                                               21


<210>  10929
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10929
gtctccacat ragtcttagt c                                               21


<210>  10930
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10930
agaatttccc ygtgatcctg g                                               21


<210>  10931
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10931
ctgtgtttca rattctctac c                                               21


<210>  10932
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10932
ggggttaaca ygaatttaac t                                               21


<210>  10933
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10933
gggcaagcct stccaaaagc c                                               21


<210>  10934
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10934
agtctagccc yggtttccaa a                                               21


<210>  10935
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10935
tggaggccaa rctctagcct c                                               21


<210>  10936
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10936
tgaaagtact ytgtgaagtg c                                               21


<210>  10937
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10937
ccaaaagtaa sttttagaat t                                               21


<210>  10938
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10938
acgttggctg ygaatcagct c                                               21


<210>  10939
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10939
acacagccct sgtttgctcg t                                               21


<210>  10940
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10940
tacaggaaaa ygtgaatggt g                                               21


<210>  10941
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10941
atgaaaacac racatccatt c                                               21


<210>  10942
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10942
taaatactaa rtttcttgtg t                                               21


<210>  10943
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10943
atatgcttgg yattccccag a                                               21


<210>  10944
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10944
gaaaacattc yacaaaggaa a                                               21


<210>  10945
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10945
ggagagaagt mtaaaatgta a                                               21


<210>  10946
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10946
ttgacacttg yggatccatt a                                               21


<210>  10947
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10947
gtcatctgga rcctccttga t                                               21


<210>  10948
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10948
cactgccaaa yggcacggtg g                                               21


<210>  10949
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10949
tctgaatgtc rgctcatcac g                                               21


<210>  10950
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10950
ttccaagggt kgaaactgta c                                               21


<210>  10951
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10951
acatctacac rtcttgtgtt t                                               21


<210>  10952
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10952
ataatgatcc rttctcaatt a                                               21


<210>  10953
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10953
gctagtaatc kctctttctt t                                               21


<210>  10954
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10954
cacgtctatc ytatcaaact t                                               21


<210>  10955
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10955
aagtaatcaa ygtgtttgtg t                                               21


<210>  10956
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10956
tttacaaaac rctttcttac a                                               21


<210>  10957
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10957
gtcgtctaac ktctttctga a                                               21


<210>  10958
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10958
ataatactca rtggttctta t                                               21


<210>  10959
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10959
gtctgctact raccgctgat g                                               21


<210>  10960
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10960
gtgctttatc yactgactta c                                               21


<210>  10961
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10961
gactcacatc rggccagtag g                                               21


<210>  10962
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10962
cattcaaact yaaggttcaa a                                               21


<210>  10963
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10963
aatggaatga sctttgtact g                                               21


<210>  10964
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10964
tgatttcaaa ygtggcaatg g                                               21


<210>  10965
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10965
gtgataggat rgtacctttg a                                               21


<210>  10966
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10966
agtccctcat yggtctctgg t                                               21


<210>  10967
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10967
acgttttctc rgtatctttg a                                               21


<210>  10968
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10968
cgtgccggtt rtccaaggca a                                               21


<210>  10969
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10969
caagtgatta ytgtagtgcc c                                               21


<210>  10970
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10970
tgggcatggt ycacgtattt a                                               21


<210>  10971
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10971
aaattttacc rtaagtacaa c                                               21


<210>  10972
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10972
tttgagggaa ygatggcatg g                                               21


<210>  10973
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10973
tcagagatct kttgtaagga t                                               21


<210>  10974
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10974
atgcctttca sactaagatg c                                               21


<210>  10975
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10975
attttgaagc mgttagacct t                                               21


<210>  10976
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10976
actaaaaatc scttattttc t                                               21


<210>  10977
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10977
accttttcag ygtgagtata g                                               21


<210>  10978
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10978
tgcacgttat sctgggttag g                                               21


<210>  10979
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10979
ggataaagta mattaacagt a                                               21


<210>  10980
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10980
catccctcaa rtagtgaaat t                                               21


<210>  10981
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10981
ctgtatttgt rgcaaagctg g                                               21


<210>  10982
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10982
acatcttttg ktctttctgt g                                               21


<210>  10983
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10983
agagcttgtg sttttctggt t                                               21


<210>  10984
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10984
ctaaccctct mgttgaatta a                                               21


<210>  10985
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10985
gtttttcaag ygtgaaatga g                                               21


<210>  10986
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10986
ggacagggct mcaaaatgat t                                               21


<210>  10987
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10987
gtactttctt rtccctctgt t                                               21


<210>  10988
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10988
tttgaaactt yatataggat t                                               21


<210>  10989
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10989
aaaagagctc ratggttggg a                                               21


<210>  10990
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10990
ttgattcatt saggcagggc t                                               21


<210>  10991
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10991
atccgcgaga stcaggcaag a                                               21


<210>  10992
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10992
ggaagcgtgg rgaacattaa a                                               21


<210>  10993
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10993
aattttagta ygcctctatc a                                               21


<210>  10994
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10994
ttgcttcagg kagttatatg g                                               21


<210>  10995
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10995
aggcagaacc yaattcaaat c                                               21


<210>  10996
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10996
ttccttatcc rtctgactta t                                               21


<210>  10997
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10997
atcttgaaat ytgaagaaga g                                               21


<210>  10998
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10998
attcctggcc ratagccact t                                               21


<210>  10999
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  10999
gattcccttt ytgaggtaag g                                               21


<210>  11000
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11000
ccggacttgt stattcaacc c                                               21


<210>  11001
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11001
aaggtcagca stctgtgcaa c                                               21


<210>  11002
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11002
gtttgccgtt rgtatttgtt t                                               21


<210>  11003
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11003
agaggcgcca rtttgactca c                                               21


<210>  11004
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11004
cctcgcccca rtgttaattc t                                               21


<210>  11005
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11005
gctaaaagga scaggtgtga g                                               21


<210>  11006
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11006
tcatggatac raggtcagca g                                               21


<210>  11007
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11007
atgttaccca ygttgaggaa g                                               21


<210>  11008
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11008
gacgactcaa kgcacagagg c                                               21


<210>  11009
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11009
ttgtgctaac ygatggacag c                                               21


<210>  11010
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11010
ttatcagcgt rctggctccg a                                               21


<210>  11011
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11011
aaggtagaaa yggcagtaag g                                               21


<210>  11012
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11012
atgatgagtt ycctgcacat a                                               21


<210>  11013
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11013
gtcttcttta yagttgagca c                                               21


<210>  11014
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11014
gcttgtactc sctctgaggt t                                               21


<210>  11015
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11015
aatcagttac mataaactta a                                               21


<210>  11016
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11016
gagacgcttt mttttacatt t                                               21


<210>  11017
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11017
gaaaccaata sactttcaga a                                               21


<210>  11018
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11018
acttagccct rtatgagtca t                                               21


<210>  11019
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11019
gaaattcttc statttatct c                                               21


<210>  11020
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11020
aaatcccatt rctagcaaac c                                               21


<210>  11021
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11021
caatatattc ragtaagtat c                                               21


<210>  11022
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11022
cttgccatga stgaaagctg g                                               21


<210>  11023
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11023
tgaggagttg ragtagcaac a                                               21


<210>  11024
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11024
gcctaatagc rcagttgatg a                                               21


<210>  11025
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11025
gcacattagt ytggtaactg a                                               21


<210>  11026
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11026
tggtgttttg rtaagtagta t                                               21


<210>  11027
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11027
ataattataa rgtttcatgt a                                               21


<210>  11028
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11028
cattttctta yaaggcgtga a                                               21


<210>  11029
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11029
tatgaacacg raaggaaata t                                               21


<210>  11030
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11030
acgtttaaat kattctgact t                                               21


<210>  11031
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11031
ctaatgagtt ratgtgctgg g                                               21


<210>  11032
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11032
caactcatga yatatatcca g                                               21


<210>  11033
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11033
tctagaaaga yatttgtgca t                                               21


<210>  11034
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11034
gttctaatga rtgaagcaga g                                               21


<210>  11035
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11035
gcctgttttt yacccttttt c                                               21


<210>  11036
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11036
tgctatatgg ratgccagtg a                                               21


<210>  11037
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11037
atggaaaact ratatgcaaa a                                               21


<210>  11038
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11038
atttgcatag maatttgcga a                                               21


<210>  11039
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11039
gagttctgtt raaaatgatt a                                               21


<210>  11040
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11040
tataaataat yagaagttgt g                                               21


<210>  11041
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11041
tttattatgc wtatcactag t                                               21


<210>  11042
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11042
ctgagtcgtt ktagtttttt t                                               21


<210>  11043
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11043
attatgaaca yctaagtaac c                                               21


<210>  11044
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11044
caattcaagg raacgatcag t                                               21


<210>  11045
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11045
ttcaacaggt ygggcaggga t                                               21


<210>  11046
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11046
tacccttgcc rtgcttgcgc c                                               21


<210>  11047
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11047
attttcagtg yaatttggac t                                               21


<210>  11048
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11048
ccagtgttgc yctgaaagat g                                               21


<210>  11049
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11049
aaacccaaat yggtcaattg g                                               21


<210>  11050
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11050
atttttccat kacagattag a                                               21


<210>  11051
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11051
accgtggata yggaaacttt g                                               21


<210>  11052
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11052
acaagtaaat saattgagct a                                               21


<210>  11053
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11053
aaggggctgc wctaggttag c                                               21


<210>  11054
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11054
gagaattgac yatagcactg t                                               21


<210>  11055
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11055
actggtgaaa sagcaaagac c                                               21


<210>  11056
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11056
tctttgtatc rttaaagaag t                                               21


<210>  11057
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11057
ctgaataatt yttcgtgtac t                                               21


<210>  11058
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11058
gttgagacac yaggaattca a                                               21


<210>  11059
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11059
aattaaaaat rtctctcaat g                                               21


<210>  11060
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11060
acattttggc rctaatacat t                                               21


<210>  11061
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11061
tcaaacagtt watgctaaaa c                                               21


<210>  11062
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11062
tttaagatcc rtaaactagt c                                               21


<210>  11063
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11063
tttacacaga raaaaagaca t                                               21


<210>  11064
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11064
aaatcatgag wcaactgggt g                                               21


<210>  11065
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11065
tcaaacaaac mctgaattca t                                               21


<210>  11066
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11066
agctggcaca yggagttctg g                                               21


<210>  11067
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11067
aggtcagtgg yacaattatg g                                               21


<210>  11068
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11068
acaattatca rttttgtgga a                                               21


<210>  11069
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11069
agtagcggtg ytgggactct c                                               21


<210>  11070
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11070
tatctaccta yatatctttg t                                               21


<210>  11071
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11071
cctattttac kgatttatgt a                                               21


<210>  11072
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11072
ttgtacattt ytgtgtctct c                                               21


<210>  11073
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11073
gaatttttgc rtatatgttt g                                               21


<210>  11074
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11074
cttagcagct rtgtgatctg g                                               21


<210>  11075
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11075
gagccaaata yacatcgggc c                                               21


<210>  11076
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11076
gagaaatggt sagactttgg a                                               21


<210>  11077
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11077
ttaaattcac rtgttaaaaa c                                               21


<210>  11078
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11078
tggtggcctc kttctctaga t                                               21


<210>  11079
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11079
atgataattc yaagctactg a                                               21


<210>  11080
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11080
tgtttatgag mtactctact g                                               21


<210>  11081
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11081
atggatattc ygaaaattcc c                                               21


<210>  11082
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11082
tgctatctgc rtgtacaaat t                                               21


<210>  11083
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11083
ggagttaagg wttattagag g                                               21


<210>  11084
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11084
atattaagtt rtgctcagat g                                               21


<210>  11085
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11085
tgtgaggatg yttagacagg g                                               21


<210>  11086
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11086
tactatatgc yttgcagacc a                                               21


<210>  11087
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11087
aaggatgttt mttcactgtg a                                               21


<210>  11088
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11088
ctattgaggc yaaagacttg a                                               21


<210>  11089
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11089
gctctacaac rctagttata a                                               21


<210>  11090
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11090
atcagtcaat mcccaaaagt t                                               21


<210>  11091
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11091
cagccagctc ygggagacac a                                               21


<210>  11092
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11092
aaaaatataa maaaggcttc a                                               21


<210>  11093
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11093
tatgtcttgt raaaagagaa c                                               21


<210>  11094
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11094
tctctatagt rtgtatttcc t                                               21


<210>  11095
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11095
ttatgaccag mcgcagaagt t                                               21


<210>  11096
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11096
gtatgaaaca rttaaattga a                                               21


<210>  11097
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11097
ccttcctgtg rcagagtggg c                                               21


<210>  11098
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11098
caggtgagag ytagcttttg a                                               21


<210>  11099
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11099
gtaaaggaag wtttcggtgt a                                               21


<210>  11100
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11100
tggacaatta wtcacatata a                                               21


<210>  11101
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11101
tagctttttt ygtgaaccaa c                                               21


<210>  11102
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11102
tttttctcca ygtacagact a                                               21


<210>  11103
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11103
cagcctaaca rgtcacatcc t                                               21


<210>  11104
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11104
tctcatcaca rtaatgctat a                                               21


<210>  11105
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11105
atcctaatcc ygattaccca c                                               21


<210>  11106
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11106
ggaacttctg kgttttttac c                                               21


<210>  11107
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11107
gggctgaacc statagagac c                                               21


<210>  11108
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11108
tgttttggat raagggacat g                                               21


<210>  11109
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11109
gagatgtgaa mtagctttta c                                               21


<210>  11110
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11110
tttcctgttc kgcaaagcag t                                               21


<210>  11111
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11111
gaacatttaa ktcttggata a                                               21


<210>  11112
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11112
ttattttcca ytaatgatat g                                               21


<210>  11113
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11113
gtcagcttca wctcttttca g                                               21


<210>  11114
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11114
gatgcagtat ktcctaacct g                                               21


<210>  11115
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11115
ggaaacactg macttttatg t                                               21


<210>  11116
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11116
ttttatctat rcctactgaa a                                               21


<210>  11117
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11117
agaatttaag ygcttattaa a                                               21


<210>  11118
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11118
ttgctgtaaa mctatatttc a                                               21


<210>  11119
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11119
ttatgaagat yaggcaactg c                                               21


<210>  11120
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11120
aaaccctgga maaagacaag g                                               21


<210>  11121
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11121
ctacgcatcc rcaccccagg c                                               21


<210>  11122
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11122
caccacctct ytcagtaacc c                                               21


<210>  11123
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11123
tcagtactca rggtctgtca g                                               21


<210>  11124
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11124
cagaacagga rttaccaaag a                                               21


<210>  11125
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11125
tggagatact yggtaaatgt t                                               21


<210>  11126
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11126
gagatgccta ygaaaataga g                                               21


<210>  11127
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11127
agagtaatct kgtggaaaga c                                               21


<210>  11128
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11128
ctggaatgat rgtgagctag t                                               21


<210>  11129
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11129
cacgtgtcaa rgaagaggcc a                                               21


<210>  11130
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11130
atgttctgtc ytatttccag t                                               21


<210>  11131
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11131
tgaggtttct sttacatgtt t                                               21


<210>  11132
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11132
agggagaaaa yagtctaaca c                                               21


<210>  11133
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11133
gcatatactt rggttgggtt t                                               21


<210>  11134
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11134
aaaactcaag maacataagg t                                               21


<210>  11135
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11135
actaaaaaca rtaacatttt g                                               21


<210>  11136
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11136
gaatctcttc ygctcacggg t                                               21


<210>  11137
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11137
atgaagaagc rgagggagat a                                               21


<210>  11138
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11138
aatgtgaaaa rtatatgtat g                                               21


<210>  11139
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11139
tgcaatttgg yttaattgta a                                               21


<210>  11140
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11140
taggaagctg ktaggtatct t                                               21


<210>  11141
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11141
tggattgaga ygtgagagat c                                               21


<210>  11142
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11142
aataatgtta ytgacagatc a                                               21


<210>  11143
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11143
gtttgaagta yggtgggtat g                                               21


<210>  11144
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11144
tgaaaaacag wttaccagta g                                               21


<210>  11145
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11145
aagtagagcc rtaaacaacc a                                               21


<210>  11146
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11146
acaagtctca rgagctatta a                                               21


<210>  11147
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11147
aatagaggac scatccatgc t                                               21


<210>  11148
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11148
ccactgtttt saagatgatt t                                               21


<210>  11149
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11149
atgactgatg yacggatgtt a                                               21


<210>  11150
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11150
ttacagggcc raggtaacaa g                                               21


<210>  11151
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11151
ctagaaaaca yttttattac t                                               21


<210>  11152
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11152
gcaaaatccg yttttcttag g                                               21


<210>  11153
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11153
ttacctttat ytggccatgt a                                               21


<210>  11154
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11154
gctggcataa rgtcatgaaa a                                               21


<210>  11155
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11155
tgaactgtta yaccacttcc c                                               21


<210>  11156
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11156
catctagcat yatcttaact a                                               21


<210>  11157
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11157
tatatttgca ygtcaactct a                                               21


<210>  11158
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11158
tcatgcgggg mctgatgaaa a                                               21


<210>  11159
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11159
ctccctctca rtcctgtagt t                                               21


<210>  11160
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11160
ctagatagag rtgaaatgct t                                               21


<210>  11161
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11161
cttacttttt ytgtcattgc c                                               21


<210>  11162
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11162
gtcaaaggct rttatgtaca g                                               21


<210>  11163
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11163
ccaagtaaaa ycaatcttac a                                               21


<210>  11164
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11164
aaaaatctta ygcatgaaga a                                               21


<210>  11165
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11165
caattaagtc ygtgaaatct t                                               21


<210>  11166
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11166
cttcaatata ygttcacaaa t                                               21


<210>  11167
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11167
ctatttgatt maacctccag c                                               21


<210>  11168
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11168
tacttatatc rtatctaaac c                                               21


<210>  11169
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11169
agaaactgtt ycctaaagcc t                                               21


<210>  11170
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11170
ctttatagaa kgtaatagtt g                                               21


<210>  11171
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11171
accttcactg mttggttaag g                                               21


<210>  11172
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11172
atttacacac rcatgcattc t                                               21


<210>  11173
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11173
aacgtgcaac mtgaaatcct a                                               21


<210>  11174
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11174
gtgtctgtta yagtaattgt g                                               21


<210>  11175
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11175
actagaatta saaataggct c                                               21


<210>  11176
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11176
aggttgctta yaaattgaat c                                               21


<210>  11177
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11177
gattttaggt yaccttgtgt t                                               21


<210>  11178
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11178
tgaatacctg mgtcatacca c                                               21


<210>  11179
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11179
gtctttaata ktttctggca a                                               21


<210>  11180
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11180
tctgtcttgg ycagtatttt c                                               21


<210>  11181
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11181
tttaatgtct rtaaaaagtc c                                               21


<210>  11182
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11182
attgaggcca maaagctcct g                                               21


<210>  11183
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11183
gaaagatgaa ragttgtgaa a                                               21


<210>  11184
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11184
tctgaaagac rccaaaagaa t                                               21


<210>  11185
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11185
gctctggatt yccaagtaaa c                                               21


<210>  11186
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11186
agtaacattt wgtaagtgat t                                               21


<210>  11187
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11187
gtcagcaagc ytggaaggaa a                                               21


<210>  11188
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11188
tggactcaca ratacattta a                                               21


<210>  11189
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11189
tgtgtcagaa wtctataatg t                                               21


<210>  11190
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11190
cagacactct rctcaaaggg t                                               21


<210>  11191
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11191
aatcatgtga rataggaaag t                                               21


<210>  11192
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11192
ctgatttaat mcttgctgcc t                                               21


<210>  11193
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11193
cttcctgcta yaatttttgg c                                               21


<210>  11194
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11194
gccttcctct ytgggcaact t                                               21


<210>  11195
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11195
aatcacagtt maattcacac a                                               21


<210>  11196
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11196
cgagagatac yggtcaggag c                                               21


<210>  11197
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11197
agagctccta yagttctccc a                                               21


<210>  11198
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11198
ggtgatcggc rcaccctaca t                                               21


<210>  11199
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11199
tctctgagcc rcaagataaa c                                               21


<210>  11200
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11200
ataagtggct ycttcaatct g                                               21


<210>  11201
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11201
catctcataa ygtggacagc t                                               21


<210>  11202
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11202
actcactcta sttgactcca a                                               21


<210>  11203
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11203
gctcactaga saatgttttc c                                               21


<210>  11204
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11204
tcatacctta rcagcataat g                                               21


<210>  11205
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11205
ttagattgtc ygagctatag t                                               21


<210>  11206
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11206
taattggcca ytgggtagat a                                               21


<210>  11207
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11207
ctacatatta rgcctggatc t                                               21


<210>  11208
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11208
ctgcctgccc rtggcttctt c                                               21


<210>  11209
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11209
atgagcacta wgtgcagtgt g                                               21


<210>  11210
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11210
ttacagacac rgtatatctc c                                               21


<210>  11211
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11211
tttccttgaa ygcatgtgtt t                                               21


<210>  11212
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11212
aagaatctgt rttcctgttg a                                               21


<210>  11213
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11213
tttactgggt ygtacctttt g                                               21


<210>  11214
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11214
taactaacac ytttatcttt a                                               21


<210>  11215
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11215
cccaggcaaa ycgaaaaggc t                                               21


<210>  11216
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11216
caggatgatc yggagaaaac a                                               21


<210>  11217
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11217
cctgggagac rtaaaggagt t                                               21


<210>  11218
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11218
gcacaatgtc rgaggccttg a                                               21


<210>  11219
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11219
accctgtcaa ytaaactatg a                                               21


<210>  11220
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11220
atttcccaca rgtagaccgg t                                               21


<210>  11221
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11221
tccttctgtt sttcagggaa a                                               21


<210>  11222
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11222
tggagttagt rgcctgcaat g                                               21


<210>  11223
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11223
tgttgaatca rttgttgagc t                                               21


<210>  11224
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11224
ctcttctgaa yagtacttct c                                               21


<210>  11225
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11225
gaaatgacag rcacctagaa t                                               21


<210>  11226
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11226
gcagaaacca yaccaataaa a                                               21


<210>  11227
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11227
aatggtagca sttggtacta a                                               21


<210>  11228
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11228
agattcagac mgcagggacg t                                               21


<210>  11229
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11229
tctctgttac rcggggtggc t                                               21


<210>  11230
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11230
atggccacaa ktaatgcttt c                                               21


<210>  11231
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11231
atatcacgga rgaaaagctc c                                               21


<210>  11232
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11232
atgaggtata rgctgcactc c                                               21


<210>  11233
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11233
agtattttgg ractggatgc a                                               21


<210>  11234
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11234
taatctctaa kggaaatctc c                                               21


<210>  11235
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11235
aaaatatgac wttttgctga a                                               21


<210>  11236
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11236
gtcttgccaa yggcctggtt t                                               21


<210>  11237
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11237
attttcattc ygttaattac t                                               21


<210>  11238
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11238
ttgagagaaa rgccgtcagt g                                               21


<210>  11239
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11239
aagaagagac matcaaaaaa g                                               21


<210>  11240
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11240
actttaagaa ytcctttttg t                                               21


<210>  11241
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11241
catgccttta stcacagaga g                                               21


<210>  11242
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11242
tagttgtgca yctgtggcac c                                               21


<210>  11243
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11243
tagtaaagtt mtgagagatt t                                               21


<210>  11244
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11244
agtttctccc rttgtctgat g                                               21


<210>  11245
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11245
cttcctcctg rtgttcaatt c                                               21


<210>  11246
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11246
agcaggtctc rtaagtactg a                                               21


<210>  11247
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11247
ataacaatca stgctgtttg g                                               21


<210>  11248
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11248
ttactcctga raactatatg g                                               21


<210>  11249
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11249
ccaacctcag ygtcatgcca g                                               21


<210>  11250
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11250
cattctaaga sacaagaaag a                                               21


<210>  11251
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11251
ggaatcagtc yctagagctc c                                               21


<210>  11252
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11252
ataaacaaac wggtcaaggg a                                               21


<210>  11253
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11253
tttagtgatg kttgggcaca a                                               21


<210>  11254
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11254
ctcttcaagg ygtggtacaa g                                               21


<210>  11255
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11255
ttgagtcctc rctctgatcc a                                               21


<210>  11256
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11256
gcagtaacag kaaacccaac a                                               21


<210>  11257
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11257
tctccatcca ytttgctggc t                                               21


<210>  11258
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11258
tttgatagta yggctgaatc a                                               21


<210>  11259
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11259
gttggccttc ratcctctag c                                               21


<210>  11260
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11260
cactatttca rtcatggcct a                                               21


<210>  11261
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11261
catgatgaca rtcagtgatc a                                               21


<210>  11262
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11262
gtggacactc yatttgacgg c                                               21


<210>  11263
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11263
atagaaataa stttttattg c                                               21


<210>  11264
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11264
catctgttcc yaggctggtt g                                               21


<210>  11265
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11265
gtcatgcacc kagttgatgg t                                               21


<210>  11266
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11266
cattgtgtct wtggtgatta a                                               21


<210>  11267
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11267
tgcagttcca ygtctcagtg t                                               21


<210>  11268
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11268
gctccataca yctgccattt t                                               21


<210>  11269
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11269
acaccctttc rgagcaaagt a                                               21


<210>  11270
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11270
atggagtaaa ygcttaaact g                                               21


<210>  11271
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11271
ttttgtcctc ygtgcctgaa a                                               21


<210>  11272
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11272
aagctgtaat mtctgaggag a                                               21


<210>  11273
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11273
ggagttaaag rgacttgaat t                                               21


<210>  11274
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11274
tcactctcca rctgttcacc t                                               21


<210>  11275
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11275
gaggctcaaa rgcacataaa a                                               21


<210>  11276
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11276
ctttttagtt ytcctgtttc a                                               21


<210>  11277
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11277
acatggtctt yttggaatgc t                                               21


<210>  11278
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11278
tgtccttaaa rcaaatggga a                                               21


<210>  11279
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11279
agaccgggct sgttcactag t                                               21


<210>  11280
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11280
ttggtaatca rctcaactag a                                               21


<210>  11281
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11281
ttgatggagg ktagatgtcc a                                               21


<210>  11282
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11282
gactgttggc raaagagtca c                                               21


<210>  11283
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11283
ttttgcctgc stgcttgagg c                                               21


<210>  11284
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11284
aaatgacatt wgacttttca a                                               21


<210>  11285
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11285
ttgaaagtta rttattggac t                                               21


<210>  11286
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11286
tctggatata yttaccatag a                                               21


<210>  11287
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11287
agttcatgga rgagcagcta t                                               21


<210>  11288
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11288
agtaactatg sctgaaaaaa t                                               21


<210>  11289
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11289
ttggaaaata ktttgtatgg c                                               21


<210>  11290
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11290
ataataacca yccacacctg a                                               21


<210>  11291
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11291
ggaatgacca mcttgttttt a                                               21


<210>  11292
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11292
actagagttc rtttcattta g                                               21


<210>  11293
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11293
tctggtaaca rttttgcagt t                                               21


<210>  11294
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11294
tgccatttat ygacaaaatg a                                               21


<210>  11295
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11295
aggtacaaag rcatacaaga g                                               21


<210>  11296
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11296
tcctcaatgc yaaagtttag g                                               21


<210>  11297
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11297
ctatcaacca rgtactgttt a                                               21


<210>  11298
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11298
gagaggaagt raaaattgca t                                               21


<210>  11299
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11299
tatacgtccc rgtctcttct c                                               21


<210>  11300
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11300
aaacaaacga wcccactcgt a                                               21


<210>  11301
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11301
ggtgggacta raaaatgtac t                                               21


<210>  11302
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11302
cttaggcact ygtggtctgt t                                               21


<210>  11303
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11303
agtcagggca raggatccag g                                               21


<210>  11304
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11304
aaaatttcct rttgtccgtg t                                               21


<210>  11305
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11305
atctccctgt ratctagatc t                                               21


<210>  11306
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11306
gctgttagcc rttgtggatt a                                               21


<210>  11307
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11307
aactctgtca mggatattag g                                               21


<210>  11308
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11308
actgtaagag kgaactccta t                                               21


<210>  11309
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11309
tgtttcctac kcagctattt t                                               21


<210>  11310
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11310
gatgctaccc yggggatcaa g                                               21


<210>  11311
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11311
tacaatcaga ygcctatttt c                                               21


<210>  11312
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11312
ccctatgtgt ycttatctgc a                                               21


<210>  11313
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11313
caatgttgaa yggagcatca t                                               21


<210>  11314
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11314
ctgggaaagg macttctttt t                                               21


<210>  11315
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11315
tagtttccac raagactctg g                                               21


<210>  11316
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11316
catgggttct rgatcttgct c                                               21


<210>  11317
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11317
ctgatcatac ytaatcttct c                                               21


<210>  11318
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11318
cttgcatctg staagacgtt a                                               21


<210>  11319
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11319
taataagtag ygtggatata a                                               21


<210>  11320
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11320
ctatccttct ycaaagagct t                                               21


<210>  11321
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11321
cacaataaca wcttgggaat a                                               21


<210>  11322
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11322
gaaaaaatct raacactata t                                               21


<210>  11323
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11323
taactgattg yagacaaact t                                               21


<210>  11324
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11324
tcatgtaggg rgtaatcact a                                               21


<210>  11325
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11325
gcttccctgg rcagcagcac t                                               21


<210>  11326
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11326
cccggttatt kcttggtgtt g                                               21


<210>  11327
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11327
tccaagggtt ytatggattg g                                               21


<210>  11328
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11328
cctgctgcct rcatttttcc t                                               21


<210>  11329
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11329
gaggaggtag yagttttctg a                                               21


<210>  11330
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11330
tctccagcat kttcttttca t                                               21


<210>  11331
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11331
gagctgttaa ytggctggtg a                                               21


<210>  11332
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11332
agaggacgca kaggcacact g                                               21


<210>  11333
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11333
atctaaagga rggttgatgg a                                               21


<210>  11334
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11334
cggatcaggc racatttcac a                                               21


<210>  11335
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11335
attgctgcat ygtgtggtaa g                                               21


<210>  11336
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11336
aatgaatgaa scccctcaac t                                               21


<210>  11337
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11337
ttatctgaac yggttcttga a                                               21


<210>  11338
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11338
tgaacattgg ytgggcgcgg t                                               21


<210>  11339
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11339
attgaaacaa ygttaagact t                                               21


<210>  11340
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11340
aaatactctt rgagagccat g                                               21


<210>  11341
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11341
ttcttttcag ytctgactct c                                               21


<210>  11342
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11342
ttcaggtctc yttccagagg a                                               21


<210>  11343
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11343
ctccacttct sttccttttg t                                               21


<210>  11344
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11344
ctctttgccg ygaggcattt t                                               21


<210>  11345
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11345
tatcaagtgt ygtgtgtcat c                                               21


<210>  11346
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11346
tatgtcactg rttaattttg a                                               21


<210>  11347
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11347
caagagcaat rgccgtacct c                                               21


<210>  11348
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11348
ggctgttctt ygcggagaac g                                               21


<210>  11349
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11349
cggagcaggg yccactgagt c                                               21


<210>  11350
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11350
ttcaaatcgt rttgcacacc t                                               21


<210>  11351
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11351
acaaaaatga ytgctggtgt c                                               21


<210>  11352
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11352
ttttacagac rcaaaagctc a                                               21


<210>  11353
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11353
gtttgtcagt sgcctgttgc c                                               21


<210>  11354
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11354
ctccaccttc rggcacagag g                                               21


<210>  11355
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11355
tgggaggtaa rtcctttctg c                                               21


<210>  11356
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11356
gagagcacac rggttgcccc a                                               21


<210>  11357
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11357
tctatgagca racaaaggag g                                               21


<210>  11358
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11358
taagaacatc rtctttcaaa a                                               21


<210>  11359
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11359
ttcacatttt rtaggagacc c                                               21


<210>  11360
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11360
tactgcattc rttaatgttc g                                               21


<210>  11361
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11361
taattaagaa rtcacctggc a                                               21


<210>  11362
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11362
aaatataagc rtagagatga t                                               21


<210>  11363
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11363
ttgttaaact rcacggtgaa t                                               21


<210>  11364
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11364
ctgtgcgtct yagccaagtg t                                               21


<210>  11365
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11365
gacaggaaag magtgccgac g                                               21


<210>  11366
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11366
tattaaagct rgaggtgttt g                                               21


<210>  11367
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11367
ctttgtctta mcatcctgac t                                               21


<210>  11368
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11368
caaggctatc mtcatatttg c                                               21


<210>  11369
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11369
ctctgtttac wttgctgctt a                                               21


<210>  11370
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11370
gcaggatgac mcatggcccg c                                               21


<210>  11371
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11371
ggggacaccc ractgagaca a                                               21


<210>  11372
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11372
tctctttcag yccctttttg t                                               21


<210>  11373
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11373
tacagacgct sacagaatag a                                               21


<210>  11374
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11374
gctgagctct kccttctgaa a                                               21


<210>  11375
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11375
aaattacaag rtataacttt t                                               21


<210>  11376
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11376
ctattgagta scttatagtc a                                               21


<210>  11377
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11377
tgtgcaaatc rtgtgattag t                                               21


<210>  11378
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11378
tttcccaaga yagttctgta a                                               21


<210>  11379
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11379
aaactgctct sttgggtgac t                                               21


<210>  11380
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11380
ttgtatctta ygtatctatt a                                               21


<210>  11381
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11381
aattctgacg rttctctacc c                                               21


<210>  11382
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11382
aaggaaaaag ygccctgcca g                                               21


<210>  11383
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11383
gtgctactta rcagatgtgt t                                               21


<210>  11384
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11384
cactgttggg yttgctgtca g                                               21


<210>  11385
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11385
atgaataaaa ygagtgctgt g                                               21


<210>  11386
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11386
ttgaagtaga saagtcaatc t                                               21


<210>  11387
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11387
aaaaatagtt ygggaaaatt g                                               21


<210>  11388
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11388
tatttacttc maagaggaca c                                               21


<210>  11389
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11389
tataagctta wacgcctaac t                                               21


<210>  11390
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11390
gatattagtt kttcatgaga g                                               21


<210>  11391
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11391
attagctacc rtcctagagt a                                               21


<210>  11392
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11392
tatttggctg ycttatccac t                                               21


<210>  11393
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11393
aggtactcca yagaaacaca g                                               21


<210>  11394
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11394
gagccatata maatgcctat g                                               21


<210>  11395
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11395
gcacactata ygacaaaaaa a                                               21


<210>  11396
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11396
ttcagccaat rcatcaattt c                                               21


<210>  11397
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11397
gagggccgta rtttttatgt c                                               21


<210>  11398
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11398
gtttttacac yagagttttg a                                               21


<210>  11399
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11399
agcactggga yaagtatcaa c                                               21


<210>  11400
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11400
caataccaca raatgtcgta a                                               21


<210>  11401
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11401
ccacttttca yaagaattga a                                               21


<210>  11402
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11402
tgtgattttg ytaattgccc a                                               21


<210>  11403
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11403
ctctacctac rcatcccaca g                                               21


<210>  11404
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11404
gtggattacc yacaacgtaa a                                               21


<210>  11405
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11405
ttccaattag ytccttttta t                                               21


<210>  11406
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11406
tctaaaaagg ycaggcaata g                                               21


<210>  11407
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11407
ctaagcccca yagatgtaag c                                               21


<210>  11408
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11408
caatttcaat wtttttatga t                                               21


<210>  11409
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11409
acacctctac yggaagaaaa c                                               21


<210>  11410
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11410
taaagaggcc kgtaccattt t                                               21


<210>  11411
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11411
tgagatgagc ytttcacctc c                                               21


<210>  11412
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11412
aaatgaaatc rgtacaggtt g                                               21


<210>  11413
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11413
tatctaattg ytgaccaccc a                                               21


<210>  11414
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11414
tacatctcaa ratcatgcca t                                               21


<210>  11415
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11415
aaaacacctt ygtcttgaga t                                               21


<210>  11416
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11416
acagtgcttt ktcagtgctg g                                               21


<210>  11417
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11417
agtggtctgc kttataccag c                                               21


<210>  11418
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11418
atcttggggt ratataacct g                                               21


<210>  11419
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11419
aatctgagac rctcattaac t                                               21


<210>  11420
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11420
atcaaatctt wcttatgctt g                                               21


<210>  11421
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11421
ttgaatatac magaccagtg c                                               21


<210>  11422
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11422
gatggacatg ytttgtctga t                                               21


<210>  11423
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11423
aatgtgaaaa mcttatgaag g                                               21


<210>  11424
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11424
attttcacct ycctgactca t                                               21


<210>  11425
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11425
gttgtgtaac rgatgattgt g                                               21


<210>  11426
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11426
cgaaagaatt stcttgatct g                                               21


<210>  11427
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11427
tgtatacaga ktgctttcaa a                                               21


<210>  11428
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11428
gggacattgg yttttattat g                                               21


<210>  11429
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11429
ctttgtaatg wtatactgga a                                               21


<210>  11430
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11430
cgtattctag yttctctgcc t                                               21


<210>  11431
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11431
gtcagcattt saagtgaatt a                                               21


<210>  11432
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11432
tgcatcaaga mgtcaaaaac t                                               21


<210>  11433
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11433
agcttaacaa yttgtgaaac a                                               21


<210>  11434
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11434
tctcactgtg mattcaatca a                                               21


<210>  11435
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11435
cttaaccctg yatttactga t                                               21


<210>  11436
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11436
tcactttata yccctgttct a                                               21


<210>  11437
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11437
acctgccatc ygctgttggg t                                               21


<210>  11438
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11438
ataaaaacca rttctagcaa a                                               21


<210>  11439
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11439
gaatagatta ygaagaaagt g                                               21


<210>  11440
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11440
cactgccttg raagagaaat a                                               21


<210>  11441
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11441
tagaaaatca rttaaggcat c                                               21


<210>  11442
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11442
gctttttatt mtgcaagctg t                                               21


<210>  11443
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11443
acccattgtg rgcctcatcc t                                               21


<210>  11444
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11444
tactggaaac kggtgggttt a                                               21


<210>  11445
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11445
tcaccattgc ygctccatca t                                               21


<210>  11446
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11446
cacacataat rcctcctttt a                                               21


<210>  11447
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11447
ggagaagagt yttctagaac c                                               21


<210>  11448
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11448
tactcaggca yacagtgttc g                                               21


<210>  11449
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11449
cccaaatatc racttgttta a                                               21


<210>  11450
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11450
ggtctcaaga sagaaaattg a                                               21


<210>  11451
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11451
ggtatgctac ragtttattg a                                               21


<210>  11452
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11452
aatgtgtatg rtccagaaac a                                               21


<210>  11453
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11453
gctaaaaaaa rtttcctttc c                                               21


<210>  11454
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11454
acattcattt ygcccctgga c                                               21


<210>  11455
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11455
gcacctaaaa mcatcccaag a                                               21


<210>  11456
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11456
tccttaggcc ractccaacc a                                               21


<210>  11457
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11457
gccttttcca rccgtgatcc a                                               21


<210>  11458
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11458
gagggtgaat yggggaagac t                                               21


<210>  11459
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11459
agcagactta ycaagtacta t                                               21


<210>  11460
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11460
caggtttacc yagaggagaa c                                               21


<210>  11461
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11461
aaaaaagaat yatgggcgaa t                                               21


<210>  11462
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11462
gcgtttaatg kctggtgact t                                               21


<210>  11463
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11463
catagtgggc mcagaggaga g                                               21


<210>  11464
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11464
tttcaaaaag sctatatctt a                                               21


<210>  11465
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11465
gttagggctt yctaaatgtt c                                               21


<210>  11466
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11466
tacgtggacc rggctgtgcg g                                               21


<210>  11467
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11467
tgcaatttgg rtgaaattaa c                                               21


<210>  11468
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11468
acattcatca mcccaccatt c                                               21


<210>  11469
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11469
aatacaggct scattctttt t                                               21


<210>  11470
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11470
tcagtaggaa yagagagtga t                                               21


<210>  11471
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11471
caatgaaaga yatgatagta a                                               21


<210>  11472
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11472
tctactgtca ytatcattct a                                               21


<210>  11473
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11473
ccagataagg wgtcactgga t                                               21


<210>  11474
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11474
ttaagacata rtcaggccat t                                               21


<210>  11475
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11475
gtgtacaaga sagaaattct t                                               21


<210>  11476
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11476
ttttcaagct wtccttattt g                                               21


<210>  11477
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11477
acagtttcta kttcctcctg a                                               21


<210>  11478
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11478
tgtaccaata rtgtgaaaag t                                               21


<210>  11479
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11479
ttctgaattg ygtttacctg t                                               21


<210>  11480
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11480
agttacatgc wtttgtgtcg a                                               21


<210>  11481
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11481
tgaactatca maagcaagat a                                               21


<210>  11482
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11482
gattattcca mgcttgcatt t                                               21


<210>  11483
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11483
ggtaaactga rctgggtatg a                                               21


<210>  11484
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11484
attgaacatt ktcttttcat t                                               21


<210>  11485
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11485
agggcattgt rgaagcatta t                                               21


<210>  11486
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11486
tcttttttaa rtaggctagt a                                               21


<210>  11487
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11487
ttaatgagag yatgcagtgg t                                               21


<210>  11488
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11488
tggcatgact sctgctggcc t                                               21


<210>  11489
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11489
tttatagaca ytatacatac g                                               21


<210>  11490
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11490
tagttagtac rcagagtgag t                                               21


<210>  11491
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11491
ctctttgccc rtcccatttc t                                               21


<210>  11492
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11492
tattttccag ytatgttggt t                                               21


<210>  11493
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11493
cctgattaaa rtgagtctta g                                               21


<210>  11494
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11494
cattactgtt kaaatcgatg c                                               21


<210>  11495
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11495
tttttgcaac wtgctctaaa a                                               21


<210>  11496
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11496
caatcaagaa rtaaaaatta g                                               21


<210>  11497
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11497
ccagtcattc ytgttccaga t                                               21


<210>  11498
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11498
agttattctc rtgatcgcag a                                               21


<210>  11499
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11499
ttgacaaaaa rtctccagtc t                                               21


<210>  11500
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11500
agcagagata rcatatatcg t                                               21


<210>  11501
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11501
attcacttac rtgatgtaac t                                               21


<210>  11502
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11502
gtttattctg rgatgctact t                                               21


<210>  11503
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11503
ctcataatgg yagcgtccgg a                                               21


<210>  11504
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11504
tgttggaaaa ygcctgtgct g                                               21


<210>  11505
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11505
gtgcttccag ytgggctaag t                                               21


<210>  11506
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11506
ttgcttattc ygagaaattt t                                               21


<210>  11507
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11507
gagtatatgc rgagaagcag c                                               21


<210>  11508
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11508
caggccttgg ycctctagct a                                               21


<210>  11509
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11509
atgatggctg rctaggactt t                                               21


<210>  11510
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11510
gaaaagatta yttgttaaca g                                               21


<210>  11511
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11511
gttacagata ycactttgaa g                                               21


<210>  11512
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11512
ccttaccttc rccagggcta a                                               21


<210>  11513
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11513
acgttttaca yttgaagcac t                                               21


<210>  11514
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11514
ccatctagga kactctggat t                                               21


<210>  11515
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11515
tgacaaggtc ytggttggtg c                                               21


<210>  11516
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11516
tcagagaaaa ktggtaattg c                                               21


<210>  11517
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11517
aaagatttct kctgaactaa g                                               21


<210>  11518
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11518
cattgagaag ytagacaaca g                                               21


<210>  11519
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11519
atttttatga scttgagata a                                               21


<210>  11520
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11520
tagaaacact ragtaggcct a                                               21


<210>  11521
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11521
tacacacaaa sattcacaga a                                               21


<210>  11522
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11522
ggcatgaaga rtttggacag c                                               21


<210>  11523
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11523
tagaaaattg ytcattctcc a                                               21


<210>  11524
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11524
aggagattag ktactggaca g                                               21


<210>  11525
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11525
tatgaaactg sgtggatggg c                                               21


<210>  11526
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11526
ataaggaaat ygaaaaataa c                                               21


<210>  11527
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11527
tttgattgga wtgctgtcct t                                               21


<210>  11528
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11528
gtgggggatg ycaccttaca c                                               21


<210>  11529
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11529
ataccatacc rcgtttcttg g                                               21


<210>  11530
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11530
agcatgctcc rgtaattgga a                                               21


<210>  11531
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11531
ttaggtcaca mtttgcattt t                                               21


<210>  11532
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11532
acattcttca kacagttatc a                                               21


<210>  11533
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11533
aacttcaccc racttcaggc a                                               21


<210>  11534
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11534
ctgtttactt yttagtctct a                                               21


<210>  11535
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11535
cattcgccta ygtaccaatg a                                               21


<210>  11536
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11536
tttagcctga yaccaagtca t                                               21


<210>  11537
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11537
aagcagaaca rctagaactc a                                               21


<210>  11538
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11538
ttttataacg ygattgaaat g                                               21


<210>  11539
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11539
caaaattggg ytttaggact a                                               21


<210>  11540
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11540
tgttaatgga sttgaatgag c                                               21


<210>  11541
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11541
ctccttccgg ycggctatca c                                               21


<210>  11542
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11542
ccctgctgcc rctttctcac c                                               21


<210>  11543
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11543
agcatgattt rgaatttatg c                                               21


<210>  11544
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11544
caccatcagg saagcagact a                                               21


<210>  11545
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11545
tgggatgctg rtgaagtgtc a                                               21


<210>  11546
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11546
catgtgcaca ratggcttta t                                               21


<210>  11547
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11547
aggcgctgaa ygaatagaac c                                               21


<210>  11548
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11548
caattgcaag rtgccctgct a                                               21


<210>  11549
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11549
taaaaacgaa mggttttggc a                                               21


<210>  11550
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11550
gttcttttcg rtgacatccc a                                               21


<210>  11551
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11551
aggaagcaat wtgaaagtga a                                               21


<210>  11552
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11552
ctttacactg stcatttttg g                                               21


<210>  11553
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11553
acaggcttag wtttctttca t                                               21


<210>  11554
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11554
tcatgggaca sagaaacaca c                                               21


<210>  11555
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11555
gaaatatgac yagcaagccc g                                               21


<210>  11556
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11556
agggttcctt yagagtgagt g                                               21


<210>  11557
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11557
tctaattggt ktcacacaag g                                               21


<210>  11558
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11558
attctactac wgttcataca t                                               21


<210>  11559
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11559
ctaaagcaat wtgatgccca t                                               21


<210>  11560
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11560
attttgatga ygtgaatctt g                                               21


<210>  11561
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11561
gtattttata raaccctcca t                                               21


<210>  11562
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11562
ataaaaattc wtgtagttga t                                               21


<210>  11563
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11563
acatgaatga staagcttcc t                                               21


<210>  11564
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11564
gtacattcca raataaaaga t                                               21


<210>  11565
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11565
aaacataaag raactaaatc a                                               21


<210>  11566
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11566
aaagagacgg rtcagtttaa t                                               21


<210>  11567
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11567
gatgtcttag ygtattacaa t                                               21


<210>  11568
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11568
tttagacaag sttaaaccca g                                               21


<210>  11569
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11569
tgtgaacgga rggtagacag a                                               21


<210>  11570
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11570
ctcatatggt yttgtggaat t                                               21


<210>  11571
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11571
caccagatgg ractttccca c                                               21


<210>  11572
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11572
tgtcaaatgg yaacaataac t                                               21


<210>  11573
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11573
ttgttcaaag ragagacaca t                                               21


<210>  11574
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11574
tgtcttctca ytaatagcac a                                               21


<210>  11575
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11575
gttatatcac mgattgagac c                                               21


<210>  11576
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11576
aatttagaac wcatttcttg g                                               21


<210>  11577
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11577
gtgtggagaa kgtgagtaac t                                               21


<210>  11578
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11578
acatgaatgt yaatttgtat c                                               21


<210>  11579
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11579
aatccgatac kctgttgatc c                                               21


<210>  11580
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11580
caaagcataa kgtggagcag t                                               21


<210>  11581
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11581
atctccccaa racaagcctt a                                               21


<210>  11582
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11582
cctcaaaact rtttctcact g                                               21


<210>  11583
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11583
cagctgtttc rgtgaatggg c                                               21


<210>  11584
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11584
taagaaggac wagggttaat a                                               21


<210>  11585
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11585
aaagcttccc rtaatacagt a                                               21


<210>  11586
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11586
ttctaacctg kaaatgaaaa a                                               21


<210>  11587
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11587
ttaataagat watttaaatg a                                               21


<210>  11588
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11588
ggttggaata raggagacca g                                               21


<210>  11589
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11589
tggcatgatg wacaaccctg t                                               21


<210>  11590
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11590
ttattcttgt kgacttgtag c                                               21


<210>  11591
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11591
aagagaagta raaggaagca a                                               21


<210>  11592
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11592
attgtaccaa ycaggttatt t                                               21


<210>  11593
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11593
cagaaggctt maattatatg t                                               21


<210>  11594
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11594
gggaaaaaaa rtcaaactag t                                               21


<210>  11595
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11595
gtttggttat yggttcccac c                                               21


<210>  11596
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11596
aggcaaccat rgaagaggga a                                               21


<210>  11597
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11597
aaacctctcc rcagatcaac t                                               21


<210>  11598
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11598
ttatgtgcca yccactaaca a                                               21


<210>  11599
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11599
ttacagaaat mctagaaact a                                               21


<210>  11600
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11600
gtaatcagtt yctacaatca a                                               21


<210>  11601
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11601
gctgaagggc mtatcgaact a                                               21


<210>  11602
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11602
agttcaggta ygtcaagaca t                                               21


<210>  11603
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11603
tcttgtgttc rtctttaaac t                                               21


<210>  11604
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11604
ttatcttaaa rccattttat c                                               21


<210>  11605
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11605
ttctggttga sagctttttt t                                               21


<210>  11606
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11606
tttaattgga sagatgtgat a                                               21


<210>  11607
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11607
cataatgagc yttaaaaccc c                                               21


<210>  11608
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11608
taattggtca yggggttaaa a                                               21


<210>  11609
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11609
gattgatgtt rttagtcgtt g                                               21


<210>  11610
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11610
attaggaaag yaattaaaat t                                               21


<210>  11611
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11611
gtccagaaca rtgacatctg a                                               21


<210>  11612
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11612
gtcggtaccc rtttgttgag t                                               21


<210>  11613
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11613
cgatgaaaat rataatcaca a                                               21


<210>  11614
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11614
ctgatcaggc raagtgagag a                                               21


<210>  11615
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11615
cctttggaaa yagcaaaatg a                                               21


<210>  11616
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11616
aacaggaagc kggtcattat t                                               21


<210>  11617
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11617
ctctctggat rgactaaata g                                               21


<210>  11618
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11618
ttagttcctc rcttatagct c                                               21


<210>  11619
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11619
attctagccc rtgctgtgac a                                               21


<210>  11620
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11620
tgttagtatg macaataggt a                                               21


<210>  11621
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11621
taagatcagc ygttgttcat t                                               21


<210>  11622
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11622
ttggaatatt ragggactga a                                               21


<210>  11623
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11623
cattaaaatt mtgtagtgat a                                               21


<210>  11624
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11624
ttctatttta ycaggaaggt g                                               21


<210>  11625
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11625
gaaaagggtg ktctatgcca c                                               21


<210>  11626
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11626
tcatatttgc mccagtgaag a                                               21


<210>  11627
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11627
gaaaattctg raagaacacg t                                               21


<210>  11628
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11628
atggggtttt kgcactcaga a                                               21


<210>  11629
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11629
catttcaata ycttaggcat t                                               21


<210>  11630
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11630
tgaatgtctt rgtcacactg a                                               21


<210>  11631
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11631
ttcatctctt mgtttttgca c                                               21


<210>  11632
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11632
cacgttttta yttgcactta a                                               21


<210>  11633
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11633
aaatgagaga wgtaacctca g                                               21


<210>  11634
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11634
tctttgccct saacattaag a                                               21


<210>  11635
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11635
gagaaaagca rtttctacat c                                               21


<210>  11636
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11636
attgctggga ytacaatcaa c                                               21


<210>  11637
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11637
ttcaaatttc rctacctaga g                                               21


<210>  11638
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11638
aacacatcgc yattaaatcc c                                               21


<210>  11639
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11639
gcaagtgtat yaatttctta t                                               21


<210>  11640
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11640
ctttctcagg ytttgctttc a                                               21


<210>  11641
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11641
tagtttaaaa ygacaacatt a                                               21


<210>  11642
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11642
gctatcataa kaagttcaaa t                                               21


<210>  11643
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11643
cattgtatgt ycatgtcatc a                                               21


<210>  11644
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11644
tttcccacgc rggtttgtct c                                               21


<210>  11645
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11645
atcatgttta rcaatcatgc a                                               21


<210>  11646
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11646
gaagatgata ragcacagac t                                               21


<210>  11647
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11647
tcatttctta rcagatcata t                                               21


<210>  11648
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11648
cttcccaaga rctcccatga c                                               21


<210>  11649
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11649
caagctcatg raaaatggaa g                                               21


<210>  11650
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11650
caggctatgc rtggattata a                                               21


<210>  11651
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11651
tgtcaacagt saattgcact t                                               21


<210>  11652
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11652
gattcttctt ygtaatgctt g                                               21


<210>  11653
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11653
tagtgtgcat maaagtgacc a                                               21


<210>  11654
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11654
aacaaacaac yttttagact c                                               21


<210>  11655
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11655
tcaatagatg sgtatgcttt g                                               21


<210>  11656
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11656
ttatgtactt ktcaacagaa a                                               21


<210>  11657
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11657
tgggaaacag ycaaggatca t                                               21


<210>  11658
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11658
attgccccca ytgtgctgaa a                                               21


<210>  11659
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11659
ttctgttgtc mttttatctc t                                               21


<210>  11660
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11660
ctgccctcat ytggatgctt t                                               21


<210>  11661
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11661
tttcaactaa ratacaatga t                                               21


<210>  11662
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11662
gtagaaactg rtaccatgct a                                               21


<210>  11663
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11663
tggtcattgg magaaataaa a                                               21


<210>  11664
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11664
ccccaaatac sttctcagtc c                                               21


<210>  11665
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11665
tattagcagt rcctagagaa a                                               21


<210>  11666
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11666
ctaaaaactc wctgtattag g                                               21


<210>  11667
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11667
aaactttaac rctaacctat a                                               21


<210>  11668
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11668
tccaactttc rtaaatgctc t                                               21


<210>  11669
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11669
aatgaaggaa satagggagc a                                               21


<210>  11670
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11670
acaaattaaa wccaggtgaa a                                               21


<210>  11671
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11671
aaagagaaat raatgggtaa t                                               21


<210>  11672
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11672
gtaccattta rtggactcca g                                               21


<210>  11673
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11673
caagtggtta yggggagaag a                                               21


<210>  11674
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11674
tagattgagt ygtggctaaa c                                               21


<210>  11675
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11675
tccaaatgta rgtacagacc t                                               21


<210>  11676
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11676
aatttggcaa wgaataaaat t                                               21


<210>  11677
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11677
acaacttcca rggagatttc t                                               21


<210>  11678
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11678
agagcattct scaacataac a                                               21


<210>  11679
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11679
tttagactgg kctatttaag a                                               21


<210>  11680
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11680
agtcataata rccaaccact t                                               21


<210>  11681
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11681
gtaagtgatt stagacaaga a                                               21


<210>  11682
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11682
aaaaaagcat wagtttcata g                                               21


<210>  11683
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11683
aacagaagag ytaatatata g                                               21


<210>  11684
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11684
caattcgaat ktttttttgt g                                               21


<210>  11685
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11685
ggtcatgtta matctttgct c                                               21


<210>  11686
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11686
atgttgggta kgtcaaggcc t                                               21


<210>  11687
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11687
gatgaacact sagataggac a                                               21


<210>  11688
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11688
actgggaaat mattcagagc t                                               21


<210>  11689
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11689
ttattggatt rtactgagaa t                                               21


<210>  11690
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11690
atcagagctc rttctaaaat a                                               21


<210>  11691
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11691
aatcagtatc wcacaataag t                                               21


<210>  11692
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11692
ggagaactag matttatgca t                                               21


<210>  11693
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11693
catggtcggc racaggccat g                                               21


<210>  11694
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11694
acaggccttc ygtcctagca g                                               21


<210>  11695
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11695
ttaccaatgc ragatcaccc c                                               21


<210>  11696
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11696
ttttgggaca rgttgcattt c                                               21


<210>  11697
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11697
ggaaattgcc rgtaattgtc t                                               21


<210>  11698
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11698
tccccagggc ycgggattgt g                                               21


<210>  11699
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11699
gatttaggcc rtcaaaaaaa g                                               21


<210>  11700
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11700
ccacaaggca rataaggact c                                               21


<210>  11701
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11701
tttagtgcag ycacattttc c                                               21


<210>  11702
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11702
aaattatttg raagtgttcc c                                               21


<210>  11703
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11703
agcaatacct kgtacagatt a                                               21


<210>  11704
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11704
ctaagtcatt stgaattcaa c                                               21


<210>  11705
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11705
cataagcacc kgaacactaa a                                               21


<210>  11706
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11706
gatcatcatc rgtacacttt g                                               21


<210>  11707
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11707
ttctttaaag kccggtcacc a                                               21


<210>  11708
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11708
cctcacgaac ractcaaagg t                                               21


<210>  11709
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11709
ctactaacta wgcccatctc t                                               21


<210>  11710
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11710
gaagttgata yctgatgaca t                                               21


<210>  11711
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11711
aatcactatt rcatcatcag c                                               21


<210>  11712
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11712
ctctggagga kactatgata a                                               21


<210>  11713
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11713
atctttgaca ytggagtaag g                                               21


<210>  11714
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11714
tctgggaaac sttctgtgtt a                                               21


<210>  11715
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11715
aaattatggc wtggaagtct a                                               21


<210>  11716
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11716
aatatagtta yatgttttca a                                               21


<210>  11717
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11717
ataacacagt rtcaattttt c                                               21


<210>  11718
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11718
gtaatgttgt ytctatacct g                                               21


<210>  11719
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11719
atcctgggct yccacatggc a                                               21


<210>  11720
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11720
tagccttgaa ygtccatcta a                                               21


<210>  11721
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11721
ttgatctgct ygcaaagata g                                               21


<210>  11722
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11722
aatgtgcaag ycttaaaaat a                                               21


<210>  11723
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11723
tgaatctccc kgcagcatct a                                               21


<210>  11724
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11724
aataacagtg yaagtgtctg g                                               21


<210>  11725
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11725
cgcatcctga watgaacacc c                                               21


<210>  11726
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11726
accaaaggta rtaaatccat a                                               21


<210>  11727
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11727
agcatagctc rgcactgttt g                                               21


<210>  11728
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11728
atgccaatgg ratgaattct g                                               21


<210>  11729
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11729
cacagtccca rcaaagacaa c                                               21


<210>  11730
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11730
tcagatgggc rtagcgggac t                                               21


<210>  11731
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11731
gcctgccaga raggggcttt c                                               21


<210>  11732
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11732
tacctggtca rcagcctggc t                                               21


<210>  11733
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11733
ccattagttg raaaactgta c                                               21


<210>  11734
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11734
attctgtgga yaaggtgaaa a                                               21


<210>  11735
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11735
tcttgaaaga ygtttgcctg c                                               21


<210>  11736
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11736
tacctttcca katctttctt c                                               21


<210>  11737
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11737
cccaactcat ygctctctgg c                                               21


<210>  11738
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11738
acatttctaa yaaaggcttc t                                               21


<210>  11739
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11739
gaattcagtg ratcatctat c                                               21


<210>  11740
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11740
agagagaaaa yggccttttg a                                               21


<210>  11741
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11741
ccctagccac rgataaaata g                                               21


<210>  11742
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11742
gtttacctgc mgacaaataa a                                               21


<210>  11743
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11743
gacttttcag wggaatgcaa t                                               21


<210>  11744
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11744
tatactgaga sgcctaggaa t                                               21


<210>  11745
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11745
ctaagaacat rgcattttat a                                               21


<210>  11746
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11746
aaaaaaatac rgagttagtg a                                               21


<210>  11747
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11747
tcacaaagca yggtgatgac a                                               21


<210>  11748
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11748
agaaactggc rtgtgataat g                                               21


<210>  11749
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11749
tttgactttt yaacccttcc a                                               21


<210>  11750
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11750
agagcatcag sgggacctca t                                               21


<210>  11751
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11751
ttaaaaaata rcaggaatta c                                               21


<210>  11752
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11752
gatttcaaac ktcttcagtt a                                               21


<210>  11753
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11753
ccagaaaagc kgtatcttcc t                                               21


<210>  11754
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11754
gtatcatcca yactgtgtat c                                               21


<210>  11755
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11755
taaaatagcg kggttaggtg t                                               21


<210>  11756
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11756
ctgtgcagta rggcaacagt c                                               21


<210>  11757
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11757
tcaacttgag rcaaagcagg a                                               21


<210>  11758
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11758
aatggtattt kctttttaag a                                               21


<210>  11759
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11759
tatcagttta mtttggtttt a                                               21


<210>  11760
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11760
tgcgctttat ygtttgtatt t                                               21


<210>  11761
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11761
gaagaagaac ragtggatat a                                               21


<210>  11762
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11762
accaccctca yggtgacagg g                                               21


<210>  11763
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11763
tcctgtgcct ygttacggtg c                                               21


<210>  11764
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11764
tggtgtgcta wctttttaat t                                               21


<210>  11765
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11765
ccttcgtttg yagagcaatg t                                               21


<210>  11766
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11766
aaagctgaat kaaaaaatca a                                               21


<210>  11767
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11767
taaacctgaa ytctaagagc a                                               21


<210>  11768
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11768
aggagttttc wcagataaaa a                                               21


<210>  11769
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11769
aaaagcatac rttagtcaca a                                               21


<210>  11770
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11770
tgatgtttac kgagggctat t                                               21


<210>  11771
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11771
tgtaagctgc mtcctggaat t                                               21


<210>  11772
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11772
tacgtgtctg yctgggatgc t                                               21


<210>  11773
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11773
cctaacgttc watttgagat t                                               21


<210>  11774
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11774
ttaagtcaca sggtgctcat t                                               21


<210>  11775
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11775
aagaaagtac rttgatggtg t                                               21


<210>  11776
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11776
tatttatttg ycccatctac a                                               21


<210>  11777
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11777
aggtgccaag kcctgtcata t                                               21


<210>  11778
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11778
aaaaaaatct rggatctaac t                                               21


<210>  11779
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11779
aatagctagg rcatttaaaa c                                               21


<210>  11780
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11780
tgtaaacatt ragaaatata c                                               21


<210>  11781
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11781
aaactcttag satatctatc t                                               21


<210>  11782
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11782
ctttgcataa rccaattata a                                               21


<210>  11783
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11783
cttgtccctc rtaagggcgc t                                               21


<210>  11784
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11784
tcttaagtgc rtttgtttat a                                               21


<210>  11785
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11785
tctagcagga katgccgtgc c                                               21


<210>  11786
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11786
ttgctaggcc matgctgctg t                                               21


<210>  11787
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11787
ttcccttcgc stctaacaca c                                               21


<210>  11788
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11788
ctaatatctt racttgatgt t                                               21


<210>  11789
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11789
aactcctacc magttcagcc t                                               21


<210>  11790
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11790
tacaaggcgg wttgttgact t                                               21


<210>  11791
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11791
gtagaagaat ytgtgagggc a                                               21


<210>  11792
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11792
gagacaggac rtacaaaggc c                                               21


<210>  11793
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11793
agaaaaacag rttaaaaaca a                                               21


<210>  11794
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11794
gattgccctc ygttagtctc a                                               21


<210>  11795
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11795
ctaggttcca ygttaccctt t                                               21


<210>  11796
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11796
ccatgatccc rtaattgttg g                                               21


<210>  11797
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11797
gagtcagcaa ygatatgctt g                                               21


<210>  11798
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11798
tgtttccata rgatctgctt c                                               21


<210>  11799
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11799
ttaagaaagt rgtgaagggc a                                               21


<210>  11800
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11800
actactcttt matctacttt t                                               21


<210>  11801
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11801
ccatttgatg rgatagtttg c                                               21


<210>  11802
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11802
tctccaaaca rtcaattttt a                                               21


<210>  11803
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11803
ccactgttat rccatctctc t                                               21


<210>  11804
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11804
tttcaaaaag ratgtagctg g                                               21


<210>  11805
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11805
actacttcta ygggaaaaga g                                               21


<210>  11806
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11806
ctgtggtaga wccaaaaatg g                                               21


<210>  11807
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11807
acatgtgagc yggcgaagat g                                               21


<210>  11808
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11808
ataaaagtta ytacatctga a                                               21


<210>  11809
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11809
cagaattgaa sagttacaaa t                                               21


<210>  11810
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11810
ctgtatattg ragatgtaga c                                               21


<210>  11811
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11811
cctctaatat mtggatttcc t                                               21


<210>  11812
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11812
tagttttgtt yatacacagg t                                               21


<210>  11813
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11813
tgcttaacta rctaaattgc t                                               21


<210>  11814
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11814
cgaatccaga rtctcaggta a                                               21


<210>  11815
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11815
aataggttca ytcaggataa a                                               21


<210>  11816
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11816
agtgtgaaac ygtttgggat c                                               21


<210>  11817
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11817
atgtctgata sagttcacta g                                               21


<210>  11818
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11818
ttgcaggaat ygcctgtgcc t                                               21


<210>  11819
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11819
gtagtgtcct scacatcggt c                                               21


<210>  11820
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11820
tggaattcaa ragacatcac a                                               21


<210>  11821
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11821
gctattctac rcagcaaatc a                                               21


<210>  11822
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11822
tactgtatga ytcaaaggct a                                               21


<210>  11823
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11823
ggaggactgg mtaatttcag g                                               21


<210>  11824
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11824
attcttgagt rataagtgga a                                               21


<210>  11825
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11825
ctaccgttac ktgaggcctt c                                               21


<210>  11826
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11826
atctaaaatc sggtgctgga t                                               21


<210>  11827
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11827
aatccagagt rgaaatacaa g                                               21


<210>  11828
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11828
acattacttg rtgtgctaag t                                               21


<210>  11829
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11829
gtgttggcca sgccaagctt g                                               21


<210>  11830
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11830
attaaccgag yattttcaaa a                                               21


<210>  11831
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11831
catgatggat raataagaaa c                                               21


<210>  11832
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11832
agccaagatg ktatacagtt g                                               21


<210>  11833
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11833
agtcctctga rcctcccttc t                                               21


<210>  11834
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11834
tctagccaca ygatgctccc t                                               21


<210>  11835
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11835
tttcttcagc rtgctaactt c                                               21


<210>  11836
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11836
ctaggtctga ygggatctct a                                               21


<210>  11837
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11837
aagtaagctc rtgaagctat t                                               21


<210>  11838
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11838
taactgtaat rtaactgcaa t                                               21


<210>  11839
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11839
tcggacaaaa rcagaaatgt a                                               21


<210>  11840
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11840
tgcgcacagc yctagggatc a                                               21


<210>  11841
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11841
tataaaattc rtgaaattaa t                                               21


<210>  11842
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11842
aaaacaagtt wtctgtatct g                                               21


<210>  11843
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11843
aattagttag yactccactg c                                               21


<210>  11844
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11844
attttggtac mtttcaaata c                                               21


<210>  11845
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11845
cttgtcccct rtttctgcag c                                               21


<210>  11846
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11846
tttcttcaga rccatatcca t                                               21


<210>  11847
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11847
ctgtatcaga rtaataaagt g                                               21


<210>  11848
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11848
acttgatagt yttatatagc c                                               21


<210>  11849
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11849
accaatagca satgacttca g                                               21


<210>  11850
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11850
tccttactgt rtgacctgct g                                               21


<210>  11851
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11851
cataacagat saaccaggtt c                                               21


<210>  11852
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11852
aaatatccaa rcactattca a                                               21


<210>  11853
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11853
atgtaagacc ratcataaaa a                                               21


<210>  11854
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11854
ttaaacaggt kgccttaagg t                                               21


<210>  11855
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11855
ggacatcacg rcagaaatta c                                               21


<210>  11856
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11856
caagtgatgc matctattga g                                               21


<210>  11857
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11857
cacatgtgac wttcgggctt a                                               21


<210>  11858
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11858
ccatgactga ygtggtgaga t                                               21


<210>  11859
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11859
gaaatttact mcgggaaggc a                                               21


<210>  11860
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11860
acacaaaaac rgagtcaaga a                                               21


<210>  11861
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11861
acatcattgc rggtactatt g                                               21


<210>  11862
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11862
tcgaacaaaa rttacctatt a                                               21


<210>  11863
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11863
tgacatgtaa rcaactttca g                                               21


<210>  11864
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11864
aacaagacta rgaagctttt a                                               21


<210>  11865
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11865
tttgaaacga sattgattta a                                               21


<210>  11866
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11866
gggacctttt mcataaagag a                                               21


<210>  11867
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11867
tatctacagg rccgtaacta c                                               21


<210>  11868
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11868
cagcagtcta ygttttgtgc a                                               21


<210>  11869
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11869
tgcctgtgtg yagcaacagt t                                               21


<210>  11870
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11870
gcttatggtg wtgaattcaa a                                               21


<210>  11871
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11871
gcatctcctg maagttaact a                                               21


<210>  11872
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11872
ggtggaagaa mctatggctg g                                               21


<210>  11873
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11873
aaacaaataa wctactttat g                                               21


<210>  11874
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11874
ataaaactaa yctccaataa a                                               21


<210>  11875
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11875
atgtgtatgc rtatgtatgg g                                               21


<210>  11876
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11876
gacatggaat rtctgtttca a                                               21


<210>  11877
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11877
ttgcaacttt sacatccagg a                                               21


<210>  11878
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11878
ttcaaatgcg ragaatcgtt t                                               21


<210>  11879
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11879
attttttctt saatgaattt t                                               21


<210>  11880
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11880
tcctttctgc rtgtgatttc g                                               21


<210>  11881
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11881
gatacctcca magtatgtgt t                                               21


<210>  11882
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11882
ataatgtgca ygtgtatctc a                                               21


<210>  11883
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11883
tgttttaagt ktgtatgttt t                                               21


<210>  11884
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11884
tattcaccac rtactctaat a                                               21


<210>  11885
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11885
ctaaacttat stgcttttct c                                               21


<210>  11886
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11886
gtttccatat ygtgttagac c                                               21


<210>  11887
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11887
cagccttgtt saagtctcta t                                               21


<210>  11888
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11888
catattccta rgtggcttcc a                                               21


<210>  11889
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11889
aaacacctga wgcaacatag t                                               21


<210>  11890
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11890
ctcctcaata yaaaatagtc t                                               21


<210>  11891
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11891
tcagtgatga yttgagactg t                                               21


<210>  11892
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11892
atctcaagga wattaagctg t                                               21


<210>  11893
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11893
ttcctcttct ycaggcttgc t                                               21


<210>  11894
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11894
cagatagcat wttgtttaac a                                               21


<210>  11895
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11895
tattctttcg yttaggagat a                                               21


<210>  11896
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11896
tggggcacca yttagcagtc c                                               21


<210>  11897
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11897
attgagctgc racatgggaa a                                               21


<210>  11898
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11898
agtggtggat rtatagttgg t                                               21


<210>  11899
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11899
agagagttct yaggaaagtt g                                               21


<210>  11900
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11900
cgaatttcac wtgagcagag c                                               21


<210>  11901
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11901
tattcttacc rttttaggtt t                                               21


<210>  11902
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11902
agtggtgggc rtatttaaga t                                               21


<210>  11903
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11903
ctgaagttca rtcataatca c                                               21


<210>  11904
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11904
aaaccttcag rgaaaaccat t                                               21


<210>  11905
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11905
acgtgggagc rctagtggac a                                               21


<210>  11906
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11906
tgccaagact rtgaggcacc a                                               21


<210>  11907
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11907
agtatctgtt yctccattca c                                               21


<210>  11908
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11908
tgtttttctc rgtgtccctc a                                               21


<210>  11909
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11909
cgtgaagcag ratttcccca g                                               21


<210>  11910
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11910
ggccagccaa yttaggtttc t                                               21


<210>  11911
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11911
tgctgcatca raaaggatta t                                               21


<210>  11912
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11912
caaggacaac rtgctttaaa t                                               21


<210>  11913
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11913
acctaggcac wttggatcat a                                               21


<210>  11914
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11914
ttatccttga wcattttacc a                                               21


<210>  11915
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11915
ggggtgatgc ytattttgtt c                                               21


<210>  11916
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11916
taatattttg ktcatctaca a                                               21


<210>  11917
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11917
ctttgtgcca ytctgtcatc a                                               21


<210>  11918
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11918
atcatctcag ygcaaagaag c                                               21


<210>  11919
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11919
catctctcag ktgtcctaga t                                               21


<210>  11920
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11920
acatgaagga yaagaaggca g                                               21


<210>  11921
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11921
acaatttcct rttgaatccc t                                               21


<210>  11922
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11922
gcttcataga ytgtgcaaca a                                               21


<210>  11923
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11923
tatttgctat kaaatccatg g                                               21


<210>  11924
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11924
tcattaatac sacaacttta g                                               21


<210>  11925
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11925
acgtaatttc yagcttaaca g                                               21


<210>  11926
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11926
ctatacgaac rtcacttctg a                                               21


<210>  11927
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11927
gaaataatct stacgaagaa a                                               21


<210>  11928
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11928
gaagtggggc ygtaaaggtg c                                               21


<210>  11929
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11929
gtgacctcct ractatcctc t                                               21


<210>  11930
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11930
ggatctgctt raagatcttt a                                               21


<210>  11931
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11931
tacaactaaa yagatcttca a                                               21


<210>  11932
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11932
ttattagcta kgtaaaagct c                                               21


<210>  11933
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11933
aagcaggatg ytgctgctac a                                               21


<210>  11934
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11934
tttagtcaca ytgaattttt g                                               21


<210>  11935
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11935
ctagtacaga yggacacagt t                                               21


<210>  11936
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11936
ttttgatggc ygcctttcaa t                                               21


<210>  11937
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11937
catggcagcc ygaacactgt c                                               21


<210>  11938
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11938
aagcctaaaa yactctgagt a                                               21


<210>  11939
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11939
catatgctca rtaaccacat g                                               21


<210>  11940
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11940
ctaaatagtc rttttttacc t                                               21


<210>  11941
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11941
gaggctccta yggagtctgg a                                               21


<210>  11942
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11942
aaatatttgc yatccataca t                                               21


<210>  11943
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11943
cttacgcatc kggataattc c                                               21


<210>  11944
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11944
cctatagatg ytattaagtt g                                               21


<210>  11945
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11945
tctaaagagt rtagtcacag a                                               21


<210>  11946
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11946
caagaacctg ygtaggctac t                                               21


<210>  11947
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11947
cccttcttct ratggaaatc c                                               21


<210>  11948
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11948
atgtgataac wtatttagtt t                                               21


<210>  11949
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11949
tgcatttcaa rgtaaccact c                                               21


<210>  11950
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11950
ccttttccac ygcctggttc t                                               21


<210>  11951
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11951
accctctgta magtcctata t                                               21


<210>  11952
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11952
ctgtcttccc kgagcaatgc t                                               21


<210>  11953
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11953
acttgcactt ytcagtagcc a                                               21


<210>  11954
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11954
agacctcctt staaatatgt t                                               21


<210>  11955
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11955
tcttctttcc rtattctaga a                                               21


<210>  11956
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11956
tgacttttag ytttggctca t                                               21


<210>  11957
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11957
aaaacaagaa ragaggcata g                                               21


<210>  11958
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11958
tcctagaaca scgtcatgtg c                                               21


<210>  11959
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11959
ctaaaagata yagactgtcc a                                               21


<210>  11960
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11960
ataaaataaa kcagaatggt g                                               21


<210>  11961
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11961
tgcaagtgcc rtgcgctatt c                                               21


<210>  11962
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11962
tagaagctgc rgacagtctt t                                               21


<210>  11963
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11963
tcttcttcct kcattagatc a                                               21


<210>  11964
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11964
tctgggttgc raatgaattt a                                               21


<210>  11965
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11965
gattatctag yttttcaagt g                                               21


<210>  11966
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11966
gagcaactaa yttaatctct a                                               21


<210>  11967
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11967
ccaggaaatg wccataagca g                                               21


<210>  11968
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11968
ttatgccaag ragtgaaggg a                                               21


<210>  11969
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11969
tatgctttca yattcggaaa t                                               21


<210>  11970
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11970
accctgaatt rtcactcaaa t                                               21


<210>  11971
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11971
tctagaaaat kctgcgcctt c                                               21


<210>  11972
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11972
cagttagttc ytacctatat g                                               21


<210>  11973
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11973
atagaagaca rctccgtatt t                                               21


<210>  11974
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11974
gcacattccc rtgctaaaga a                                               21


<210>  11975
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11975
catcttctta ytctgtcgtg a                                               21


<210>  11976
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11976
atttctcttg yaaaaacctt c                                               21


<210>  11977
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11977
caggaagcta ygaaataaag a                                               21


<210>  11978
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11978
cacattgctc rtaattctga t                                               21


<210>  11979
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11979
tttggagaag rcagaagcta t                                               21


<210>  11980
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11980
gtgaaatagt wtccattgca t                                               21


<210>  11981
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11981
tcatggtaca mggccaagaa a                                               21


<210>  11982
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11982
ggatttaata yatgacttct g                                               21


<210>  11983
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11983
agtgctagtt rgatgtgaaa g                                               21


<210>  11984
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11984
gtgaaaaaat ygttggcatc t                                               21


<210>  11985
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11985
gaacaaaaat ygcctcttga t                                               21


<210>  11986
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11986
ttggatggga racaaacata c                                               21


<210>  11987
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11987
ttgcagcaat rtggtcctaa t                                               21


<210>  11988
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11988
tagtaaatta wcccacaaga g                                               21


<210>  11989
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11989
ctggggtgaa yactcattgt g                                               21


<210>  11990
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11990
aacatgttct yatttctcaa t                                               21


<210>  11991
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11991
tctttaattc rttgtaactg g                                               21


<210>  11992
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11992
tcattttgga rgtacagaag g                                               21


<210>  11993
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11993
agttatctaa ygctttcaaa t                                               21


<210>  11994
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11994
atcataatat rcagtttgaa c                                               21


<210>  11995
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11995
tttcaagggc rgaaaaaggc t                                               21


<210>  11996
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11996
ctttcttgat rttagtccac g                                               21


<210>  11997
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11997
catgtatcta ytaatgaaca t                                               21


<210>  11998
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11998
tttatggtgc yttctatact t                                               21


<210>  11999
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  11999
gagcaagctc yatacaggaa g                                               21


<210>  12000
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12000
acattcaggg ycttatagac g                                               21


<210>  12001
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12001
ttttcaaaag ractcaacca a                                               21


<210>  12002
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12002
gaaaaggtga ygcaaaaatt t                                               21


<210>  12003
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12003
tcctcaggcc ytttcttttc c                                               21


<210>  12004
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12004
catagcccaa ytactacttg a                                               21


<210>  12005
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12005
tatattaaaa ygaaatggac t                                               21


<210>  12006
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12006
gtatcccata yagcaagaag t                                               21


<210>  12007
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12007
gtgacacagt rtctatacta t                                               21


<210>  12008
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12008
cttaacttcc rgattccaca g                                               21


<210>  12009
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12009
tgttgccata ycactgtgta g                                               21


<210>  12010
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12010
ccaacaaaat rgacttacat g                                               21


<210>  12011
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12011
ctgttagaca ygacacagtc t                                               21


<210>  12012
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12012
agccatatac rgtcattaaa a                                               21


<210>  12013
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12013
gcgacctctc mtaaactttg t                                               21


<210>  12014
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12014
caatgatcgg mtagtaaagt a                                               21


<210>  12015
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12015
taaggaatta staggcattt a                                               21


<210>  12016
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12016
actcaacatt rcctaaaaac t                                               21


<210>  12017
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12017
tcccataatg watcagcttc a                                               21


<210>  12018
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12018
agtttatcta ygccggcaag c                                               21


<210>  12019
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12019
gttcacatag yggtgttatt a                                               21


<210>  12020
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12020
ggatttcaca ytgcaaacta a                                               21


<210>  12021
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12021
ccgaattagc rcctaggaga c                                               21


<210>  12022
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12022
tccattacag yggtcctgag g                                               21


<210>  12023
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12023
accaccgcct ytgtcaagct g                                               21


<210>  12024
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12024
aagagctgtg ytaatacttt t                                               21


<210>  12025
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12025
tttctggcta yaagctcatt t                                               21


<210>  12026
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12026
gggctgaccc wggcgataca a                                               21


<210>  12027
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12027
attgactatc ytcgtttcct c                                               21


<210>  12028
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12028
gagggcactg ygggcacttt a                                               21


<210>  12029
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12029
tcaattaagg rttttattta c                                               21


<210>  12030
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12030
tcctagaata ygctgaattt a                                               21


<210>  12031
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12031
gcatatagat ygaggccaac a                                               21


<210>  12032
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12032
ggaaagtttc ytttttggta a                                               21


<210>  12033
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12033
cttttcatat kccttacaag t                                               21


<210>  12034
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12034
attcttcata yaaaaacttc t                                               21


<210>  12035
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12035
ttttctgcag rtattcccag g                                               21


<210>  12036
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12036
ctatgcttat ygatggcaat c                                               21


<210>  12037
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12037
gtctccctca ygctcagttt c                                               21


<210>  12038
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12038
tttattttcc rtatatttcc a                                               21


<210>  12039
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12039
attaagaatc ygtatactga g                                               21


<210>  12040
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12040
cagagtcagt rgggagcaaa t                                               21


<210>  12041
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12041
acaggacatc rcttatggca a                                               21


<210>  12042
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12042
atgtctgaaa yggtgcgagt a                                               21


<210>  12043
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12043
ggaccacgcc yggaaggatg t                                               21


<210>  12044
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12044
agtgaccgac ygcacccgct g                                               21


<210>  12045
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12045
tgagatactt yggagcaacc t                                               21


<210>  12046
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12046
caagaactgc ytgggagata c                                               21


<210>  12047
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12047
atccacctgg ytttgagtag a                                               21


<210>  12048
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12048
atctcattca scacttctcc t                                               21


<210>  12049
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12049
ttcatggcaa yagactgctg g                                               21


<210>  12050
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12050
ttgcctttgc ratcatggtg t                                               21


<210>  12051
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12051
catagccaat sctggtcctt c                                               21


<210>  12052
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12052
caagggttac rctcataaac a                                               21


<210>  12053
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12053
aagctcaggt kccagatccc t                                               21


<210>  12054
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12054
ataacttact kgatgacact t                                               21


<210>  12055
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12055
ccacaggaga yaattctgtg c                                               21


<210>  12056
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12056
gcccttgggt wtcatagagc a                                               21


<210>  12057
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12057
tgcttgggcg yacccttggc c                                               21


<210>  12058
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12058
gtataacaca kagggaacct g                                               21


<210>  12059
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12059
aaatatttaa ygattcttgg t                                               21


<210>  12060
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12060
ctttgttttc mgaaactact t                                               21


<210>  12061
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12061
ctgatagaaa rcattcttaa a                                               21


<210>  12062
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12062
ctaagattaa ytgtaggagg t                                               21


<210>  12063
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12063
gagagtaaga yttataaacc t                                               21


<210>  12064
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12064
ctttgtgaac rccggcagtg a                                               21


<210>  12065
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12065
taatcttttt stcactacag a                                               21


<210>  12066
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12066
actgtgcatg rcacctacat g                                               21


<210>  12067
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12067
gaccctggac ycactcagct g                                               21


<210>  12068
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12068
aggccctgca wagcttgtaa c                                               21


<210>  12069
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12069
tcttcatatg rctggttcca t                                               21


<210>  12070
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12070
caggaacaga ygcatttggt a                                               21


<210>  12071
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12071
ccgcatgatg sagaaatggg a                                               21


<210>  12072
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12072
gtgggctaca kctttcactg t                                               21


<210>  12073
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12073
gggaagtttc yggatgtctg c                                               21


<210>  12074
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12074
ggatgacatc satgattctc t                                               21


<210>  12075
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12075
acagacccat ycacagcagg c                                               21


<210>  12076
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12076
tctccgcatg ygggactctc g                                               21


<210>  12077
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12077
attgtattgg ytacaatggc t                                               21


<210>  12078
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12078
aaggtataaa sgcaaaatat t                                               21


<210>  12079
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12079
tagtggtgta yggagatcaa t                                               21


<210>  12080
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12080
gattaaatca rttggtaaat g                                               21


<210>  12081
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12081
caacaaactt ygtcaaactt g                                               21


<210>  12082
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12082
tctgaggaat matttgagaa a                                               21


<210>  12083
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12083
attgctttaa rtgcacaatt t                                               21


<210>  12084
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12084
ctggtgtggc mccatctgaa g                                               21


<210>  12085
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12085
tgtcctaaac wtagaaaagg a                                               21


<210>  12086
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12086
ttatatgcac yagaatttct g                                               21


<210>  12087
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12087
atgcacatac rcagagaagg a                                               21


<210>  12088
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12088
tcagctatta wgtcttagtc a                                               21


<210>  12089
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12089
ccaatgaagc mtgaaattat t                                               21


<210>  12090
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12090
tcttagttat stttatttta t                                               21


<210>  12091
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12091
ccacccaata ygaaagcaac t                                               21


<210>  12092
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12092
acaagcaagt mgtagtctga g                                               21


<210>  12093
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12093
ttaaatattg yatagaggtc a                                               21


<210>  12094
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12094
gctgaggtca rggctcagta c                                               21


<210>  12095
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12095
ggcacagtag raggtgtggc c                                               21


<210>  12096
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12096
atgtcataaa sagctaagcc t                                               21


<210>  12097
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12097
ctagtcaaag stagaaaggg c                                               21


<210>  12098
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12098
tctgggacca ytggaaaagg g                                               21


<210>  12099
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12099
tggcgtaggt rggtggttct a                                               21


<210>  12100
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12100
tctgggtaaa ygtaaagaaa g                                               21


<210>  12101
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12101
tgctcaaatc rtaagtgagg a                                               21


<210>  12102
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12102
gatgaagcca rtaactgtaa g                                               21


<210>  12103
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12103
ccacagttgg ygacgctttc a                                               21


<210>  12104
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12104
caaaacaggt mttataatca t                                               21


<210>  12105
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12105
aattgtagga sgcagagcag c                                               21


<210>  12106
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12106
agatgaaagt wtttatcaac c                                               21


<210>  12107
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12107
cgaactagga ycttgcatgt a                                               21


<210>  12108
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12108
actgattaca ytgtcgcaca g                                               21


<210>  12109
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12109
agatacaagt kcacttattg t                                               21


<210>  12110
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12110
ctaaaatggt rctttgctat a                                               21


<210>  12111
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12111
aagcagagcc kctctacctg a                                               21


<210>  12112
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12112
ctctattatg mcatctcttt t                                               21


<210>  12113
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12113
agaaagatat rcagacaatt a                                               21


<210>  12114
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12114
tccatttcta sagaatcctt g                                               21


<210>  12115
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12115
atagcatcca yatgattctg t                                               21


<210>  12116
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12116
taagtaactc yagagcatag g                                               21


<210>  12117
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12117
taagcatttc scaattacaa t                                               21


<210>  12118
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12118
taaaatgacc rataggtata a                                               21


<210>  12119
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12119
atcaagttac statacaaga g                                               21


<210>  12120
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12120
tattgccata yagggtgatt t                                               21


<210>  12121
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12121
tcttatgaag wttttattat a                                               21


<210>  12122
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12122
taatttctgg yattatagtg a                                               21


<210>  12123
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12123
gggccataaa rctttcaaga a                                               21


<210>  12124
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12124
ttaggtcttt rgaggcccct c                                               21


<210>  12125
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12125
ctgtgtcttc rgatgcagcc t                                               21


<210>  12126
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12126
tgagagagaa ragccagggt t                                               21


<210>  12127
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12127
ctcttgggag kgcatccaca t                                               21


<210>  12128
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12128
cgcaaaatag rtgttcaaca t                                               21


<210>  12129
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12129
agcacttgac rtatgacccc a                                               21


<210>  12130
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12130
ctcagctccc rtttctcatg g                                               21


<210>  12131
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12131
ctgttagaaa ygcctccagg t                                               21


<210>  12132
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12132
acgtctgtct yaagtttcaa g                                               21


<210>  12133
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12133
tgcatacagt kgctacacct c                                               21


<210>  12134
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12134
tgaaaggtgg ygagtagcgg g                                               21


<210>  12135
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12135
tgaggctgga yggtaaactg a                                               21


<210>  12136
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12136
acatagtcct ycgctccaca c                                               21


<210>  12137
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12137
aagcctgata rctgtcctag a                                               21


<210>  12138
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12138
taaactactg rtggatgcta t                                               21


<210>  12139
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12139
gtgagtcccc rggtcagggc a                                               21


<210>  12140
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12140
ataattatgg ygtgcccact c                                               21


<210>  12141
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12141
tcagtcttac rgtcaggtaa a                                               21


<210>  12142
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12142
acaatgtata yagaactttc t                                               21


<210>  12143
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12143
tttaaccatc raagaatcat c                                               21


<210>  12144
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12144
taacaactgc wtgtaaacga a                                               21


<210>  12145
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12145
tggtatctcc rtggtgatgc a                                               21


<210>  12146
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12146
gctcagtgaa raactcacca t                                               21


<210>  12147
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12147
attgctgact yatcggatgc c                                               21


<210>  12148
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12148
agttacgcac rtggcgtggc a                                               21


<210>  12149
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12149
tgaatacaca wgaccggtga c                                               21


<210>  12150
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12150
tacttgggaa stggcggcct c                                               21


<210>  12151
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12151
agcttcagtg rgcaaattcc g                                               21


<210>  12152
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12152
gatatcgtaa raaatactaa g                                               21


<210>  12153
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12153
agggcttcga rcttatacat g                                               21


<210>  12154
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12154
gtagctatcc rgagagtttg g                                               21


<210>  12155
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12155
ttcccagctg rggacatcac g                                               21


<210>  12156
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12156
aagctcttgg ygggctccag t                                               21


<210>  12157
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12157
ccttagggag racacccttc t                                               21


<210>  12158
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12158
cagggattat rcaagggtaa a                                               21


<210>  12159
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12159
ctgaaataat yaaacatgtt c                                               21


<210>  12160
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12160
ttccatatag yggtcaataa g                                               21


<210>  12161
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12161
ttgtgtaggg sttttaccat c                                               21


<210>  12162
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12162
catttataga ytatctgtaa g                                               21


<210>  12163
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12163
tgaaaacatg rtcagctcca t                                               21


<210>  12164
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12164
accaagtcct rcaacacaag t                                               21


<210>  12165
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12165
cctctccttt kacggcactt c                                               21


<210>  12166
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12166
tcgtactttg ygttgtgaga c                                               21


<210>  12167
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12167
ttttctgtta ygctgctaat c                                               21


<210>  12168
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12168
acttttgtaa yatatgactt a                                               21


<210>  12169
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12169
cgtcatcagg wtgtgaggtt t                                               21


<210>  12170
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12170
agactggaat raatatgagg a                                               21


<210>  12171
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12171
tgatttatct mcacagattt c                                               21


<210>  12172
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12172
ttgtagctaa ytgcaagccc a                                               21


<210>  12173
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12173
ttctagccct yaaattcatc t                                               21


<210>  12174
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12174
aaatttcaag rttcatttca t                                               21


<210>  12175
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12175
attagaataa yattgctgca t                                               21


<210>  12176
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12176
tttcacaaac yacctggttt a                                               21


<210>  12177
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12177
taaagttgta yatgaatatt a                                               21


<210>  12178
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12178
cagactccag ygcactctat c                                               21


<210>  12179
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12179
actgtgaatt yctgtatagc a                                               21


<210>  12180
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12180
gaggtgctca rtaatattca a                                               21


<210>  12181
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12181
cctctgcagc rttcctgggc a                                               21


<210>  12182
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12182
aaaaatgttt ktgaacacag t                                               21


<210>  12183
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12183
ttttacccta ygtttaactt t                                               21


<210>  12184
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12184
tgctgattca rtgaactttt g                                               21


<210>  12185
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12185
cattcaaagg rtgacaggca g                                               21


<210>  12186
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12186
gcaagacagg raaatacagt t                                               21


<210>  12187
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12187
gtatgttaca yccagattat t                                               21


<210>  12188
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12188
tatgacagtt yctactcatc t                                               21


<210>  12189
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12189
ggtagaaaat ytgagaagtg a                                               21


<210>  12190
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12190
atttgctggt rcacacaatt t                                               21


<210>  12191
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12191
agttttccaa matatctttt c                                               21


<210>  12192
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12192
aaaagaagca rcaccatatt a                                               21


<210>  12193
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12193
tttcaggcag stcttttcat t                                               21


<210>  12194
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12194
gccttacatt wgttacttta c                                               21


<210>  12195
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12195
aagcccatat ygactgtgga c                                               21


<210>  12196
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12196
tagatgcttc yggctataag a                                               21


<210>  12197
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12197
attttggtgc ycaggagaac a                                               21


<210>  12198
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12198
gtcaagttca yatctaggga t                                               21


<210>  12199
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12199
aacttcacag rgtcatgcag t                                               21


<210>  12200
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12200
aatctttacc raaggtgcac a                                               21


<210>  12201
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12201
gtataggtac rcgaaaacag t                                               21


<210>  12202
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12202
ggtctggctg rtgctttcaa a                                               21


<210>  12203
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12203
tgtaaaacgt ygtcatcttc a                                               21


<210>  12204
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12204
cactcagcac wtaatcatct t                                               21


<210>  12205
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12205
ctcctcaaaa mcattatctt c                                               21


<210>  12206
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12206
gccaaaccag ractctattt t                                               21


<210>  12207
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12207
acatcctttt ytccctcttg g                                               21


<210>  12208
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12208
tatttcctcc rtaattcggt a                                               21


<210>  12209
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12209
gttggagaca ratacatggt t                                               21


<210>  12210
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12210
attagtcttt sagatgtccc t                                               21


<210>  12211
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12211
tgagaaggag rtttggcatt g                                               21


<210>  12212
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12212
ctatttgata ycttgttgaa t                                               21


<210>  12213
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12213
tctcagggtc rtgttctttg g                                               21


<210>  12214
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12214
aggtttcaaa ytccagtgtg c                                               21


<210>  12215
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12215
atttcttttg wcagcttaca g                                               21


<210>  12216
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12216
ttgctagata sgaatggtgg t                                               21


<210>  12217
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12217
tctagataca saaataaaga t                                               21


<210>  12218
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12218
ttaacttttt rttcagaaca g                                               21


<210>  12219
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12219
tccaagcctt ygaaatactt g                                               21


<210>  12220
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12220
gccttgcaaa matttataaa a                                               21


<210>  12221
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12221
ttagagggca rtggaaagca t                                               21


<210>  12222
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12222
atttctgagc ktgaactttc c                                               21


<210>  12223
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12223
tttggtacag rttaacttgt t                                               21


<210>  12224
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12224
taactgttaa yaacgatgat g                                               21


<210>  12225
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12225
atgtcaagaa ytctgaatta g                                               21


<210>  12226
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12226
ctttactttg rccccaaatt a                                               21


<210>  12227
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12227
gacgagaaaa rctaaatgtg g                                               21


<210>  12228
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12228
agacgagcat ygccactcag t                                               21


<210>  12229
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12229
agactaaatg mggattttta a                                               21


<210>  12230
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12230
ttatctgtct ygctctccat a                                               21


<210>  12231
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12231
ggaggctcat kgtgtctgca t                                               21


<210>  12232
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12232
tgctttatac wttttggagg t                                               21


<210>  12233
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12233
ataaacttgg raaacacgat a                                               21


<210>  12234
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12234
aagaaacatg saattcaaga g                                               21


<210>  12235
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12235
aaacttgttg rtaccctttg a                                               21


<210>  12236
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12236
gaccatctca ytcactcacg t                                               21


<210>  12237
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12237
acaggtcagc rcggaggact t                                               21


<210>  12238
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12238
tgtgtgttta yggtgtttgg c                                               21


<210>  12239
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12239
gcttccatcc yattcttctt c                                               21


<210>  12240
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12240
tgtgctagaa kgaaccctgc a                                               21


<210>  12241
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12241
gatctgtatt ytcacatccc t                                               21


<210>  12242
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12242
ctgtggaaat rtccaggcac a                                               21


<210>  12243
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12243
acttcagtta maagaaaata a                                               21


<210>  12244
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12244
gagcaggtgc ytactgtatg g                                               21


<210>  12245
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12245
attcatgccc ragggaatgt t                                               21


<210>  12246
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12246
agcactaaat sgcctcccct g                                               21


<210>  12247
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12247
ccaaaaaaac ygctgtttga a                                               21


<210>  12248
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12248
accaagcctt rttatcctgg t                                               21


<210>  12249
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12249
tttctccata ytgtatgttt a                                               21


<210>  12250
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12250
ggaggtgaag ytgttgaaat g                                               21


<210>  12251
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12251
acctctgtgg rttcctaagt a                                               21


<210>  12252
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12252
gaatgtttgg rgaatttcaa t                                               21


<210>  12253
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12253
gtgggtaagt wtgtgtgtta c                                               21


<210>  12254
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12254
acctggttct saaagacact g                                               21


<210>  12255
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12255
atattatctg rcgttttggg a                                               21


<210>  12256
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12256
tatcaaaagc rctgagcttt a                                               21


<210>  12257
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12257
ggaacagctc mtaatgacat g                                               21


<210>  12258
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12258
ttagacatgt yatgcaacgt c                                               21


<210>  12259
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12259
tgtaattaaa ygaccattac t                                               21


<210>  12260
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12260
tatttactga mttctctttc t                                               21


<210>  12261
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12261
ggcatacaaa rgtcctcaca c                                               21


<210>  12262
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12262
acttagggga rgcaatgcta g                                               21


<210>  12263
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12263
tcttcaatcc mtaaggtatt a                                               21


<210>  12264
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12264
cagtataatc yttgcttaaa t                                               21


<210>  12265
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12265
caactgtaat satggtactg a                                               21


<210>  12266
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12266
cagcattgct rtagtatgtc a                                               21


<210>  12267
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12267
agctgaaatg yacagagacc t                                               21


<210>  12268
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12268
gccagctctt kggagttctg c                                               21


<210>  12269
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12269
catgccacac kgtattttct g                                               21


<210>  12270
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12270
ggcatattta matgaatggt t                                               21


<210>  12271
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12271
atgttgttac ygtaccttag a                                               21


<210>  12272
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12272
gacttgacct yggaggagat c                                               21


<210>  12273
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12273
tgaagaacta mgatggaatg a                                               21


<210>  12274
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12274
gtcgtctgat rtaacttgcc a                                               21


<210>  12275
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12275
cagcttagta stttttttct a                                               21


<210>  12276
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12276
tctaggatac ycctaccttg a                                               21


<210>  12277
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12277
tcttcaatat scgagctaaa t                                               21


<210>  12278
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12278
actgccctct rgtgtcactt t                                               21


<210>  12279
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12279
accctgctac ytaggaccta g                                               21


<210>  12280
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12280
ccttaggaga yacccagtac a                                               21


<210>  12281
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12281
gataaaggcc rctgatcatt g                                               21


<210>  12282
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12282
ggaaagtagc rtttacacca t                                               21


<210>  12283
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12283
agtcggaatc raaccagcac c                                               21


<210>  12284
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12284
aaagggaggt ratacaggat t                                               21


<210>  12285
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12285
ggagttatct mcccacatgg c                                               21


<210>  12286
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12286
acgtgatgct rtgcaaaggc t                                               21


<210>  12287
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12287
atcatattgt ytttccagtg a                                               21


<210>  12288
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12288
cgatttgtct yggcacgaat c                                               21


<210>  12289
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12289
tgtcagaaat magtctgctc a                                               21


<210>  12290
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12290
tccgagaaac wtcatgtcta c                                               21


<210>  12291
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12291
aaggacaact ragtggaaat a                                               21


<210>  12292
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12292
cttatcactt ygttgttcta t                                               21


<210>  12293
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12293
gtttgtctaa saataaagag g                                               21


<210>  12294
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12294
ctttgttgcc mttttatata t                                               21


<210>  12295
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12295
atactgtagc ytgagtgact t                                               21


<210>  12296
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12296
atgcagtgga yggaagaagg a                                               21


<210>  12297
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12297
tctttctact saggttcatt g                                               21


<210>  12298
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12298
gtatagccca ygctaagctt t                                               21


<210>  12299
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12299
agagtgactt yagtctgttc c                                               21


<210>  12300
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12300
atgaagtcat ytggacaggt t                                               21


<210>  12301
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12301
gaagccgatt mctctggcta g                                               21


<210>  12302
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12302
agtttaaaag rtatttcacc t                                               21


<210>  12303
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12303
ggttcctggt yttcagtagc a                                               21


<210>  12304
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12304
atcttctaac yagaggagag t                                               21


<210>  12305
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12305
ctgtccaata yagttcctgc c                                               21


<210>  12306
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12306
taacatgtcc ytgacacttg a                                               21


<210>  12307
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12307
cgtcttctat wtgacagggg a                                               21


<210>  12308
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12308
ttgagtgaat rgctgctgaa a                                               21


<210>  12309
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12309
aattgctttc yaaatccaac g                                               21


<210>  12310
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12310
ggtagcttac yagtactttc c                                               21


<210>  12311
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12311
cacaatagaa raaaacatca g                                               21


<210>  12312
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12312
tgctcaacaa ygagtaaggg c                                               21


<210>  12313
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12313
tcagacagat wagcaaagac t                                               21


<210>  12314
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12314
agaggaaatc kgtgcaaatc c                                               21


<210>  12315
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12315
aaatcacctt yttggccggg t                                               21


<210>  12316
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12316
gttgatctgt ytgtatactc c                                               21


<210>  12317
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12317
cctttgaata ycctcgtttt g                                               21


<210>  12318
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12318
aagtgtcctg mtttcacaga t                                               21


<210>  12319
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12319
ctgtctagta ytcaggaaat g                                               21


<210>  12320
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12320
tttcaataaa wataggaagc a                                               21


<210>  12321
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12321
tgattgttct rgtggatgaa c                                               21


<210>  12322
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12322
agtcaacttg rttacacaca g                                               21


<210>  12323
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12323
gtaaagtaag yagtgaaaca a                                               21


<210>  12324
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12324
tttcaggtag ygacagagca g                                               21


<210>  12325
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12325
ctccacatct saatttctac t                                               21


<210>  12326
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12326
aaatgctcac kctaaatggc a                                               21


<210>  12327
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12327
agattattta rtgaaaccaa t                                               21


<210>  12328
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12328
cattttactt wtggtgacca t                                               21


<210>  12329
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12329
tggagtcatt saatcaccca a                                               21


<210>  12330
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12330
ttgaaagttg kgtaaagcat c                                               21


<210>  12331
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12331
ctatatgcta ygtttatatg t                                               21


<210>  12332
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12332
tccacagtat yggtcaatta a                                               21


<210>  12333
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12333
gaagcagtat rgacttttaa a                                               21


<210>  12334
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12334
ttgggaaatg yggataatac c                                               21


<210>  12335
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12335
aggacctgtt yctaaaataa c                                               21


<210>  12336
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12336
tgaactgagc mgaagctttt a                                               21


<210>  12337
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12337
aattgtctag rcatcttgca g                                               21


<210>  12338
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12338
actggttact ygctgatctc t                                               21


<210>  12339
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12339
atgacattgc ragtagaagc t                                               21


<210>  12340
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12340
agaagcaata rtaagaccct a                                               21


<210>  12341
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12341
accctttttt ytgaagacca a                                               21


<210>  12342
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12342
aaaaaatgag rttaaaaaac a                                               21


<210>  12343
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12343
aacatttgat ycctaactgt g                                               21


<210>  12344
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12344
caaaggaaga yctgtagaca t                                               21


<210>  12345
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12345
caattcatat wccaggagca c                                               21


<210>  12346
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12346
cctcttagtg yttccccagc c                                               21


<210>  12347
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12347
cctagggcac rctcaatata t                                               21


<210>  12348
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12348
gcatttcaca yggagagagg g                                               21


<210>  12349
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12349
gggagtgggc maaatgactt a                                               21


<210>  12350
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12350
ggaagcatct rctataaaac c                                               21


<210>  12351
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12351
agcctgccat ytcatggtgg a                                               21


<210>  12352
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12352
taccagattt satggttgat t                                               21


<210>  12353
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12353
acagtcattt ytcagctatt g                                               21


<210>  12354
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12354
atagcttcat ycacagggac a                                               21


<210>  12355
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12355
aggaaagtca ygggactgcc a                                               21


<210>  12356
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12356
agatctcaca racaagacac a                                               21


<210>  12357
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12357
ctaaatagag yctacttccc a                                               21


<210>  12358
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12358
tgttgaaatg raaacacaca c                                               21


<210>  12359
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12359
cagtttagtt rgtttagtca g                                               21


<210>  12360
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12360
tgaaagaatc rcttcatgga g                                               21


<210>  12361
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12361
tccaaataaa yagacccatg g                                               21


<210>  12362
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12362
tgtgtggcag rcctttagga a                                               21


<210>  12363
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12363
agcatgcccc rcctgaatat g                                               21


<210>  12364
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12364
agtgaagtcc mgatataaca g                                               21


<210>  12365
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12365
tctaatttcc rtttatcctg c                                               21


<210>  12366
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12366
gcttacatac rcaagggttt g                                               21


<210>  12367
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12367
gatgacattt ygtctgtttt c                                               21


<210>  12368
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12368
ttttacaaag yctgtgttag a                                               21


<210>  12369
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12369
tggtgtctcg yaccgccagc t                                               21


<210>  12370
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12370
ggaatgctgg yggacttggc t                                               21


<210>  12371
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12371
gcctgcccaa ygcttgtccc t                                               21


<210>  12372
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12372
ggctgttact yttttctgtg t                                               21


<210>  12373
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12373
tagtatgtga yaggagcctc g                                               21


<210>  12374
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12374
gctggtgaag yatacatcct g                                               21


<210>  12375
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12375
cagattcaat yctagaactt t                                               21


<210>  12376
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12376
ttgtgccagc rttatgagga c                                               21


<210>  12377
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12377
ctccagtcag kttaaggggt c                                               21


<210>  12378
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12378
ttgccttatc kggggtgcac a                                               21


<210>  12379
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12379
gtttatgtct rtagatggat a                                               21


<210>  12380
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12380
agtaccctta ytccatctcc c                                               21


<210>  12381
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12381
tttttattgt rtctgtatcc t                                               21


<210>  12382
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12382
ctgtcaatca rgagagtgaa a                                               21


<210>  12383
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12383
agagagtttg rgaatcaatg c                                               21


<210>  12384
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12384
tatccaaaga ytgcatttct g                                               21


<210>  12385
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12385
gcgtccataa ycttaattca t                                               21


<210>  12386
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12386
gagaaggagg stgatgtcaa a                                               21


<210>  12387
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12387
gtcacatcac ytataaaagt t                                               21


<210>  12388
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12388
atcagtacca ytaagatcat t                                               21


<210>  12389
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12389
tctttgtaaa ygaatcatca c                                               21


<210>  12390
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12390
tgtaccatca yccacttctt t                                               21


<210>  12391
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12391
tgatgtgctt sacagccctt g                                               21


<210>  12392
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12392
acaactcata ygaagatttt t                                               21


<210>  12393
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12393
ttcttagcct rgcaggaaac a                                               21


<210>  12394
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12394
ttctcatttg ratagttatg a                                               21


<210>  12395
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12395
gaatagaaac wagttggtca c                                               21


<210>  12396
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12396
aaagctggga ragaggatat g                                               21


<210>  12397
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12397
ataataaaaa sccaggaagc a                                               21


<210>  12398
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12398
catagtaaca sagacacaat t                                               21


<210>  12399
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12399
tggggagata rtatttcttc t                                               21


<210>  12400
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12400
tcctgtctgg rttctgagga t                                               21


<210>  12401
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12401
gaaatgtagc yagaacatat t                                               21


<210>  12402
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12402
ctaggggatc rcatttaagc c                                               21


<210>  12403
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12403
atattgagca yttttccacg a                                               21


<210>  12404
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12404
ttggcattca ragaaataca a                                               21


<210>  12405
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12405
ttcttgggat mgttcattct g                                               21


<210>  12406
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12406
cactgcaggg ytacagggat g                                               21


<210>  12407
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12407
gtgttgcctc yttctgactc a                                               21


<210>  12408
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12408
cagaatgtag rtacatatag g                                               21


<210>  12409
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12409
ctctgtggca yaaattacac a                                               21


<210>  12410
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12410
taaagcaggt ktcaagctgc c                                               21


<210>  12411
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12411
tgtgtgttcc yagatctgag a                                               21


<210>  12412
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12412
ttcctccaag yggaggctga g                                               21


<210>  12413
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12413
atagaggaag stcttttaat a                                               21


<210>  12414
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12414
attggaatgc ytcttcatac a                                               21


<210>  12415
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12415
ctcacttccc rtaactgctg a                                               21


<210>  12416
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12416
accatggctt maagtggagg a                                               21


<210>  12417
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12417
ttcatagtaa rtaaacttgc t                                               21


<210>  12418
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12418
catgaatggg kccaacatga a                                               21


<210>  12419
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12419
caggagaaaa rctgtccctg g                                               21


<210>  12420
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12420
ccagaagaaa kaacagtatg t                                               21


<210>  12421
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12421
tatatgtgag yctagaggta a                                               21


<210>  12422
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12422
ggttgctcca ygaagaaaag a                                               21


<210>  12423
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12423
cccaatgcca yacactgagc g                                               21


<210>  12424
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12424
agttgccatt ygcttgtcac c                                               21


<210>  12425
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12425
gacaatacca wgttcatgct a                                               21


<210>  12426
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12426
tgctgtgtca wagtctgtat c                                               21


<210>  12427
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12427
gacaattcac ractcaccag g                                               21


<210>  12428
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12428
tattaaagat ytgatacatt t                                               21


<210>  12429
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12429
tttttctaca saattgcaca t                                               21


<210>  12430
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12430
cctttgtctt ktcttagcat c                                               21


<210>  12431
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12431
actttgtata yatgaaccta a                                               21


<210>  12432
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12432
tcacatcaaa ytgataaaaa t                                               21


<210>  12433
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12433
gagctgcatg ytgccctcca t                                               21


<210>  12434
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12434
accagtaagt mtcaagcaag t                                               21


<210>  12435
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12435
atcaggcagg rtacgttaca a                                               21


<210>  12436
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12436
gcattaactt rgcgcccggg g                                               21


<210>  12437
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12437
ttgccccctc rtggcagtct c                                               21


<210>  12438
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12438
tagtgaagag rggtctaaag t                                               21


<210>  12439
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12439
ccacatactc macatgcatt t                                               21


<210>  12440
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12440
tttagggaag raaatgactg t                                               21


<210>  12441
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12441
gctttgcgta ygattgtgtt t                                               21


<210>  12442
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12442
aacacagata ygaaaataat a                                               21


<210>  12443
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12443
tcacctgtgt yacccttacc t                                               21


<210>  12444
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12444
aactgatgtt kctgtccctt t                                               21


<210>  12445
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12445
gtttccacaa ygaagagaaa a                                               21


<210>  12446
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12446
ttaaatgaag rggctcatat t                                               21


<210>  12447
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12447
tagctcacat ytgatggtta c                                               21


<210>  12448
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12448
caaagggcta stgttgcatg g                                               21


<210>  12449
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12449
agaggtgaaa yaggctcatc c                                               21


<210>  12450
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12450
tcgttccttt ytcaaactct t                                               21


<210>  12451
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12451
gatttcctga yttcctgaaa t                                               21


<210>  12452
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12452
tctggtagca ygtgttctag c                                               21


<210>  12453
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12453
tggtcaagaa yggcgtcatg g                                               21


<210>  12454
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12454
agttcacctc rtagtaacac a                                               21


<210>  12455
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12455
tcaaaccccg rgaactagac a                                               21


<210>  12456
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12456
gacacactat rtgctaaata t                                               21


<210>  12457
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12457
tctgcacagt sctcttgtct g                                               21


<210>  12458
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12458
ttggagctgg magttcctgg g                                               21


<210>  12459
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12459
cctgagactc ygaggaccaa a                                               21


<210>  12460
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12460
gatgaaaggc rctctccgtg g                                               21


<210>  12461
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12461
gcttaaaagc magggtgcag t                                               21


<210>  12462
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12462
gtatatttgc ygcttcccca a                                               21


<210>  12463
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12463
attttgaagt wttcatgcaa g                                               21


<210>  12464
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12464
acagtgctgg yccctggtct a                                               21


<210>  12465
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12465
acactgagaa raagtatggg c                                               21


<210>  12466
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12466
agtgtagatc raataagcat t                                               21


<210>  12467
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12467
ggggtccatt rttcctatca g                                               21


<210>  12468
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12468
cttactataa yactaggcag t                                               21


<210>  12469
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12469
cagaaaacac rcaaggctgg g                                               21


<210>  12470
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12470
gttcatacgc rgtacaagaa g                                               21


<210>  12471
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12471
tgttatccct kcataaacac t                                               21


<210>  12472
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12472
ggaagagccc rgtgagaagg a                                               21


<210>  12473
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12473
tccacaacaa rtttataatc a                                               21


<210>  12474
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12474
aagaaaaccc rcaaaaatga t                                               21


<210>  12475
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12475
ctctgtgcac ygtctcttac a                                               21


<210>  12476
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12476
tattgtttgg yatcattctg g                                               21


<210>  12477
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12477
aatggaagta waaaaacagt t                                               21


<210>  12478
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12478
agtggacctt rgcaatgaca g                                               21


<210>  12479
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12479
tttgtttaat sagctcctgg a                                               21


<210>  12480
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12480
gcaggacttc rtctcatggt a                                               21


<210>  12481
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12481
tttaagtgct rtggatcacc a                                               21


<210>  12482
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12482
tcgttcaaac rttcagccaa a                                               21


<210>  12483
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12483
ctaccagcat ycatactaat c                                               21


<210>  12484
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12484
ccctggaaac rttgctattc a                                               21


<210>  12485
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12485
tggaaggagc ygggttctaa a                                               21


<210>  12486
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12486
gcctgtgtgc rgaagtatag t                                               21


<210>  12487
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12487
caggtacata rcactttaca a                                               21


<210>  12488
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12488
acctttcctc yagttttttc c                                               21


<210>  12489
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12489
caaaagctgt ygaatccttc t                                               21


<210>  12490
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12490
gcgacacgtt ytgtgggacc c                                               21


<210>  12491
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12491
catttcatca rtagtccctg g                                               21


<210>  12492
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12492
tgtagacatg wttcccgcct a                                               21


<210>  12493
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12493
ttctctctta ygcttctgta g                                               21


<210>  12494
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12494
gactccagga rgaaatgagg g                                               21


<210>  12495
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12495
acagaggaga magagcccag g                                               21


<210>  12496
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12496
gagaagtggg rtcataaaat c                                               21


<210>  12497
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12497
caatgttttt ycatggtgag a                                               21


<210>  12498
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12498
gccttagaag sagatttgga t                                               21


<210>  12499
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12499
attcaccttt ktaatctgtc c                                               21


<210>  12500
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12500
tggaaaaagc rttattgaaa a                                               21


<210>  12501
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12501
aaggggtaac rtgtatgagt g                                               21


<210>  12502
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12502
gctatattct yctgttctta a                                               21


<210>  12503
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12503
agtagatctt rttattactg c                                               21


<210>  12504
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12504
gtagagtgtg ygctctgcct t                                               21


<210>  12505
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12505
tttgggaatt kccctcctcc g                                               21


<210>  12506
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12506
tgggttcaaa ycccagatgt a                                               21


<210>  12507
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12507
aaaaacagtg ragtatttta a                                               21


<210>  12508
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12508
cttttcagct ytcatccctt t                                               21


<210>  12509
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12509
ttgtgtaaaa yaaaccatac a                                               21


<210>  12510
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12510
atatgtttca ytgcaaaccc a                                               21


<210>  12511
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12511
gtattgtcac rtaggtttga a                                               21


<210>  12512
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12512
tgccatacct kttatgttat c                                               21


<210>  12513
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12513
aggtttttcc yacccctact t                                               21


<210>  12514
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12514
ccacttaatg ytaaacttgg a                                               21


<210>  12515
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12515
ggttcacaat kaacatattc t                                               21


<210>  12516
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12516
aaaagctctg kccccaggaa t                                               21


<210>  12517
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12517
ctggatggta mgagactcat a                                               21


<210>  12518
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12518
atcagtgtgt yccacttagg t                                               21


<210>  12519
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12519
tgattggaat ygacgcagat c                                               21


<210>  12520
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12520
tgcacttacc satgatttca t                                               21


<210>  12521
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12521
tatcatcatt ytgaaaaaac c                                               21


<210>  12522
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12522
catgaaatat kagtatgcag g                                               21


<210>  12523
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12523
ccaagttttc rtagccctgt a                                               21


<210>  12524
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12524
tggagggggc ratattggag c                                               21


<210>  12525
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12525
cctcagctca raaaccctct a                                               21


<210>  12526
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12526
tgtttgccat kaagtcacaa c                                               21


<210>  12527
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12527
ttgtatcttt yttccaaggt t                                               21


<210>  12528
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12528
tgcagaatca scgttggtac a                                               21


<210>  12529
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12529
tcaaaatgca yaaggaaacc c                                               21


<210>  12530
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12530
tgaagcaaat stcacattaa t                                               21


<210>  12531
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12531
ttaaccttta ygttttgatg t                                               21


<210>  12532
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12532
gcattttaaa ycatcattgt c                                               21


<210>  12533
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12533
catttcaact rtgtacactt a                                               21


<210>  12534
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12534
aactaaatta yctggacata t                                               21


<210>  12535
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12535
ctaaaggaga yggttgggta a                                               21


<210>  12536
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12536
aacaaaaatg rtctcaaaag t                                               21


<210>  12537
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12537
atgaacttgg ygtcagagtc a                                               21


<210>  12538
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12538
gagctgactc ygtgtgaata a                                               21


<210>  12539
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12539
tccgtacagc wtggaaaaat a                                               21


<210>  12540
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12540
agaactttcc rtcaaacatc t                                               21


<210>  12541
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12541
accgctcgcc rttgtgcctg a                                               21


<210>  12542
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12542
tcgttgtgca raagcttggt g                                               21


<210>  12543
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12543
gggacgctta ygttccattc t                                               21


<210>  12544
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12544
ttccaccctc rgaagcaggc c                                               21


<210>  12545
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12545
gcatacctct ytgagaacca t                                               21


<210>  12546
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12546
ataaatccat sgggaaagtg a                                               21


<210>  12547
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12547
gtttctgcat stagatttca c                                               21


<210>  12548
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12548
atgtgataca rttcatattc a                                               21


<210>  12549
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12549
ccacagtttg ycattgtgtg a                                               21


<210>  12550
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12550
gatttaattt ygttttaaag g                                               21


<210>  12551
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12551
aagtactcct rggatttctg c                                               21


<210>  12552
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12552
ggcaattgca yaggaggcag c                                               21


<210>  12553
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12553
atctagcttt rttcagtaga t                                               21


<210>  12554
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12554
cactgagaaa yacaacgatg g                                               21


<210>  12555
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12555
agatctaaga ragatgatgt t                                               21


<210>  12556
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12556
aaacggttaa wggagttgct t                                               21


<210>  12557
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12557
gagattccag ygaaaatcag c                                               21


<210>  12558
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12558
gcgttagaac rcagattgcc g                                               21


<210>  12559
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12559
ttagaattcc rtctcgttct g                                               21


<210>  12560
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12560
aagttggatt rtgtatatta t                                               21


<210>  12561
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12561
atacagatta ygtgcaaaaa a                                               21


<210>  12562
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12562
aaatttgcac rtgtgtggtt t                                               21


<210>  12563
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12563
tatattcatc rataccaatt g                                               21


<210>  12564
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12564
atgagggaac ygaagatagc a                                               21


<210>  12565
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12565
ggattaagga rcagtgagag c                                               21


<210>  12566
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12566
attacttaaa sacactgtaa t                                               21


<210>  12567
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12567
tacaaaagga ytcactaacc t                                               21


<210>  12568
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12568
aaagggctaa yggaagcctg g                                               21


<210>  12569
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12569
cagaatccca mtgaaataac c                                               21


<210>  12570
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12570
gatagccctc rcttgctaag c                                               21


<210>  12571
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12571
gcatgtatca rtatattttt g                                               21


<210>  12572
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12572
aaggcaaatg rgaatcactg g                                               21


<210>  12573
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12573
acatattttc rccaagtgac c                                               21


<210>  12574
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12574
ggacttgcac rttacactag a                                               21


<210>  12575
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12575
attcttgatg ratccaaagt g                                               21


<210>  12576
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12576
ttgcatcccc yggtacattg a                                               21


<210>  12577
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12577
cctaattaac rttcttccaa g                                               21


<210>  12578
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12578
tatgtttcat ragccttgtc a                                               21


<210>  12579
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12579
gacagtgatc rgatgtgcgg a                                               21


<210>  12580
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12580
ggtgaagcca rtaaaaagta a                                               21


<210>  12581
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12581
tcaacatcac rtggggtacc a                                               21


<210>  12582
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12582
aaatgtgaca yaatcaatta c                                               21


<210>  12583
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12583
ttacaactga ygtaagggcc t                                               21


<210>  12584
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12584
tcaacaagaa stagcccata a                                               21


<210>  12585
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12585
gtctgagttc mtcctggtaa a                                               21


<210>  12586
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12586
gaaaagatgc raactaaatt g                                               21


<210>  12587
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12587
gcccaccttt ytctgcaagc c                                               21


<210>  12588
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12588
gaagagttac magtgggatg c                                               21


<210>  12589
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12589
aattatacat ytatgcatcc a                                               21


<210>  12590
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12590
ggaattattt stcttataac t                                               21


<210>  12591
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12591
tgtccttaaa statactgaa c                                               21


<210>  12592
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12592
actcagcaca rtcaaatatg a                                               21


<210>  12593
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12593
ctaatgctac ktaggacttc t                                               21


<210>  12594
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12594
ggcttccctg sggataaaat a                                               21


<210>  12595
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12595
cgtcacacaa racaagaggc a                                               21


<210>  12596
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12596
gaagagggaa sgttgggtaa g                                               21


<210>  12597
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12597
gtacaaccac yggggcaggt a                                               21


<210>  12598
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12598
gtctgactgt raacagaaga c                                               21


<210>  12599
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12599
agtaagttgg ytttgaaaag a                                               21


<210>  12600
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12600
atgtgaacta ytcaggagaa a                                               21


<210>  12601
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12601
actttgaata yacgtaaatg t                                               21


<210>  12602
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12602
tgcctgagag stgcccagag a                                               21


<210>  12603
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12603
acagagtaga rgcttaggat g                                               21


<210>  12604
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12604
tgaataataa rcctgtaata g                                               21


<210>  12605
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12605
actgataaca rtagaggttt c                                               21


<210>  12606
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12606
tttgttactc mgtctgcatg t                                               21


<210>  12607
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12607
tattgtaaag ygtttgcaaa t                                               21


<210>  12608
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12608
atgatactta yacttgaatc a                                               21


<210>  12609
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12609
tactcaactg ytcttaactt a                                               21


<210>  12610
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12610
attgaggggc rtacagaaat a                                               21


<210>  12611
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12611
tcaatcatgc ytctttgaac c                                               21


<210>  12612
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12612
tttacggtat mttttgtttg c                                               21


<210>  12613
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12613
tcttgctcac rctgtatttc t                                               21


<210>  12614
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12614
gtttgctgcc rtctgaaata t                                               21


<210>  12615
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12615
tagtttctag yctaaggctt t                                               21


<210>  12616
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12616
aaggcttact ytatgcatac g                                               21


<210>  12617
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12617
atactattcc yatttttagc a                                               21


<210>  12618
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12618
agttacaaaa wcagttctct c                                               21


<210>  12619
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12619
acctagcaca raagatttca t                                               21


<210>  12620
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12620
ttgtattgta yatcaaccat a                                               21


<210>  12621
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12621
gcactgtgct rttctctcat g                                               21


<210>  12622
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12622
taggacctgg yagggcaacc t                                               21


<210>  12623
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12623
cagtttgtgg yttgtctttt a                                               21


<210>  12624
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12624
acccctgctc wagcatatct g                                               21


<210>  12625
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12625
tgaaaactga mccagtcaat t                                               21


<210>  12626
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12626
agaggaatga sagctgatgc a                                               21


<210>  12627
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12627
taggtaactt yataaactgc c                                               21


<210>  12628
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12628
ttttcgtaag yagacagact c                                               21


<210>  12629
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12629
ggtttcatat ytatttcctt c                                               21


<210>  12630
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12630
acgggtatct rtacacaaat a                                               21


<210>  12631
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12631
aaacgttatc racaaattat t                                               21


<210>  12632
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12632
aaaatggaaa rcagtgtcca g                                               21


<210>  12633
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12633
agggatgatt sagcagggag t                                               21


<210>  12634
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12634
ttggaaaaaa rttccatttg c                                               21


<210>  12635
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12635
attttcagag wttgctcata g                                               21


<210>  12636
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12636
acagtcccta yggtacaaga g                                               21


<210>  12637
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12637
agtttcttat rttgtcaatt a                                               21


<210>  12638
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12638
ttattctgtc ytagtattta a                                               21


<210>  12639
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12639
gggaaactgg mgtgaggaga g                                               21


<210>  12640
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12640
tcattgttca ragggtcact t                                               21


<210>  12641
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12641
tactttgtgg yttttggaaa g                                               21


<210>  12642
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12642
agtagcacgc rtaccctcag a                                               21


<210>  12643
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12643
gctcagaaat kctaaaattc c                                               21


<210>  12644
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12644
acagcagtga yatttcaact g                                               21


<210>  12645
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12645
gtagagtatt sgacatttag t                                               21


<210>  12646
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12646
tggtttagcc kaagtttaca t                                               21


<210>  12647
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12647
actgttctta ygtaatgctg g                                               21


<210>  12648
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12648
gtcagtcctg wggccatgga a                                               21


<210>  12649
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12649
gcagaggaga mattggttta a                                               21


<210>  12650
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12650
attttgttca ygtttcattt g                                               21


<210>  12651
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12651
cacataccta ytgagctgca a                                               21


<210>  12652
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12652
ttcctcatca wtctgtcaat t                                               21


<210>  12653
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12653
gtatttgtag ytccctcatt c                                               21


<210>  12654
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12654
aattctaaaa ycaggaaagc t                                               21


<210>  12655
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12655
tgcttaaaac rcttccatgg t                                               21


<210>  12656
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12656
gaacccataa ytttggaagc t                                               21


<210>  12657
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12657
cagttaatag sgctttctat t                                               21


<210>  12658
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12658
ctgaatttga ytaccactgt t                                               21


<210>  12659
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12659
cacagtcccg rgcacacagt g                                               21


<210>  12660
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12660
agaaatcttc rtgccaagtt a                                               21


<210>  12661
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12661
cccttgctct yaggcaaaag t                                               21


<210>  12662
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12662
catctctcac kacaggaccc c                                               21


<210>  12663
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12663
aagtcttcag ytgggttcca t                                               21


<210>  12664
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12664
acagtagtac rtgcttcaag a                                               21


<210>  12665
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12665
tcaccactgg ycctgataac a                                               21


<210>  12666
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12666
gccctcttgt ytctggcttt t                                               21


<210>  12667
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12667
agataccaat rtctcagtga g                                               21


<210>  12668
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12668
ttcctgcttg mccctgctca g                                               21


<210>  12669
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12669
tggtgaggca rgctttcaag t                                               21


<210>  12670
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12670
ttcccttggg ktttctctcc c                                               21


<210>  12671
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12671
cctcatgacc mcttattagt a                                               21


<210>  12672
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12672
aaatgttcct rgaggtcttc t                                               21


<210>  12673
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12673
tttctcaaca yggtttttac a                                               21


<210>  12674
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12674
ccttcttacc rgaaccttgt g                                               21


<210>  12675
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12675
cttgtttagt ycttcattca g                                               21


<210>  12676
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12676
ggcctgggcc rctggatagc t                                               21


<210>  12677
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12677
gctctgtgaa rcatgttcac a                                               21


<210>  12678
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12678
tgagtagaac ygggccagtt g                                               21


<210>  12679
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12679
gctcagtgac rtcaacagga t                                               21


<210>  12680
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12680
ctggaaggtc rggaaatcca g                                               21


<210>  12681
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12681
tatctcatgg kgaaaagtga a                                               21


<210>  12682
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12682
tagggaactt rgggcccagt c                                               21


<210>  12683
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12683
tgaaattggc ygaaaagaca t                                               21


<210>  12684
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12684
actgggcatc yggagagagg g                                               21


<210>  12685
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12685
aatcattctc stttacagaa c                                               21


<210>  12686
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12686
agtatagaaa ycagaatata t                                               21


<210>  12687
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12687
tgattttcct yaacctcctt c                                               21


<210>  12688
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12688
cctgccacct ygctcttgtt t                                               21


<210>  12689
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12689
ttttgttgac ytaattacct c                                               21


<210>  12690
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12690
tgtcactcat rgatgaatca c                                               21


<210>  12691
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12691
tttattcaca ycttgacaaa t                                               21


<210>  12692
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12692
ccaaaccacc rgtccagaaa t                                               21


<210>  12693
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12693
cccatgagtt rtaaattttt t                                               21


<210>  12694
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12694
atgctaagga rtcatttcct a                                               21


<210>  12695
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12695
tgggatgatt rtctacacct g                                               21


<210>  12696
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12696
atgtttactc rcggagaact g                                               21


<210>  12697
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12697
gtgagagtta yttatttcta t                                               21


<210>  12698
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12698
ttataaaaaa stccttgttg c                                               21


<210>  12699
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12699
ggatttgaga sgccaagatc t                                               21


<210>  12700
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12700
tttgaatgct rgtttcatat t                                               21


<210>  12701
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12701
atctttggac rttttacccc c                                               21


<210>  12702
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12702
acaaacatgg macattgatt g                                               21


<210>  12703
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12703
attactgcta wtaagaatgg c                                               21


<210>  12704
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12704
cttctgttct rtatctacat g                                               21


<210>  12705
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12705
aaccagtttc rtgtttcata t                                               21


<210>  12706
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12706
gagtcatttt ygcttatctc a                                               21


<210>  12707
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12707
tagagtagaa ycatgctgta a                                               21


<210>  12708
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12708
ttatggaatg mgaagtttta t                                               21


<210>  12709
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12709
gcccataagg satattttgc a                                               21


<210>  12710
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12710
tttcatgtca rtgggtatga a                                               21


<210>  12711
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12711
tactgttagc scctttggca a                                               21


<210>  12712
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12712
agtgaggtgc rtgtgataat g                                               21


<210>  12713
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12713
ccaaatgtga ygttattaca g                                               21


<210>  12714
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12714
agttgatgaa raggcattgg a                                               21


<210>  12715
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12715
acagctccct ygtaattttt a                                               21


<210>  12716
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12716
gtgctgatga yggccatgat g                                               21


<210>  12717
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12717
agcttccagg rcctctttct c                                               21


<210>  12718
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12718
catctacttg yatgtccttc a                                               21


<210>  12719
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12719
tagcaatacc rcatttattt t                                               21


<210>  12720
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12720
tgatgccata kttaaatatg a                                               21


<210>  12721
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12721
caacctgaac waagaacaaa a                                               21


<210>  12722
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12722
cgttttgcca yatcagcaac c                                               21


<210>  12723
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12723
aatagagttt sccagaatta a                                               21


<210>  12724
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12724
caaagtctgg saaagttgcc t                                               21


<210>  12725
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12725
cattggagaa rcatgaaggc a                                               21


<210>  12726
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12726
cttcactgtt ratactgaaa a                                               21


<210>  12727
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12727
gacatatggc raagattata t                                               21


<210>  12728
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12728
tactggccaa mtgaaaatta a                                               21


<210>  12729
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12729
ggggtcagag yggtggttgt t                                               21


<210>  12730
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12730
aacagacacg rgtatttaat t                                               21


<210>  12731
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12731
cagatagatt yggtggaagc t                                               21


<210>  12732
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12732
tcacccaaaa kagtaaatat t                                               21


<210>  12733
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12733
tatttccctt yccgtggccc a                                               21


<210>  12734
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12734
atctctcttt yaaaacataa c                                               21


<210>  12735
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12735
tgagcccttc raaacatcag c                                               21


<210>  12736
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12736
ttggtgattc yctccacctc t                                               21


<210>  12737
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12737
tagtgattac matcttggat g                                               21


<210>  12738
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12738
acaggttttt yctgggagcc t                                               21


<210>  12739
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12739
ttcttttttt yggttatctg t                                               21


<210>  12740
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12740
agcaccagcc raaatgtttg a                                               21


<210>  12741
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12741
ttcttattcc raaattacac t                                               21


<210>  12742
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12742
ggatgatggg rccataaaag t                                               21


<210>  12743
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12743
tagtttccac rtcatttttg t                                               21


<210>  12744
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12744
ggattgcaca yatcatttgg a                                               21


<210>  12745
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12745
caagggcggt rccaagactt c                                               21


<210>  12746
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12746
agggcatgct yagatcaccc t                                               21


<210>  12747
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12747
tacccacgat ycttcaaagt g                                               21


<210>  12748
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12748
taggtgattc ycctaaacat c                                               21


<210>  12749
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12749
gccacgcttc saaaggaaaa a                                               21


<210>  12750
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12750
tgcacttgtg rcctctcctt c                                               21


<210>  12751
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12751
gggaatcagg rccttgagtt c                                               21


<210>  12752
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12752
tcctgagtaa mtccacacac a                                               21


<210>  12753
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12753
tgaaaacata mattgtggcc c                                               21


<210>  12754
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12754
gtgaaacaca ktccttctgt a                                               21


<210>  12755
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12755
ttgaatttag ygatgttaag g                                               21


<210>  12756
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12756
ctgctatgct stgtgttcaa g                                               21


<210>  12757
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12757
gtctgcaacg ytgaatttgg a                                               21


<210>  12758
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12758
tgggtgtttt stcattcttt g                                               21


<210>  12759
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12759
ctccttgttc yatagtatat t                                               21


<210>  12760
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12760
tctctgaatt rtgggtttag g                                               21


<210>  12761
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12761
tctggggctt kggaaagtca c                                               21


<210>  12762
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12762
ccttcaaaaa yggatagatt t                                               21


<210>  12763
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12763
tgctgatatt kcgtgtctct t                                               21


<210>  12764
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12764
tgaggttgag raagtattgc c                                               21


<210>  12765
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12765
ctttaattat mcctgattgg g                                               21


<210>  12766
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12766
tttaaagatt kagtaactta t                                               21


<210>  12767
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12767
tcagaccctg rtaggcataa g                                               21


<210>  12768
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12768
gcaaaggctg ktctgattac a                                               21


<210>  12769
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12769
aagtttccat ygaagataaa g                                               21


<210>  12770
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12770
aatagtagca mtgtatgcct t                                               21


<210>  12771
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12771
taataatttc rgtctttaaa t                                               21


<210>  12772
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12772
tgggtttgcc yacaacttca g                                               21


<210>  12773
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12773
gccttcacag wcaacatttg a                                               21


<210>  12774
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12774
aggtgagaga sagcatctca g                                               21


<210>  12775
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12775
ttaatgcatt yagcttgaat a                                               21


<210>  12776
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12776
aatgtatcat yttatggtgt g                                               21


<210>  12777
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12777
tcaacaaatc ytcttattgt c                                               21


<210>  12778
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12778
gatttcttca yagcaatgtt c                                               21


<210>  12779
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12779
gagaaagccc kccttagaaa a                                               21


<210>  12780
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12780
ccgagcaaga rgcaactgta t                                               21


<210>  12781
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12781
aaacagtcct yggtgtccgc t                                               21


<210>  12782
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12782
tttttttttt sagaactcca a                                               21


<210>  12783
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12783
gacaaaaaag kaagggattg c                                               21


<210>  12784
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12784
tcatttcctg ragagttacg g                                               21


<210>  12785
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12785
taagaatgct wattgctgct a                                               21


<210>  12786
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12786
agtcaataac raaatccaca t                                               21


<210>  12787
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12787
tttcgtgtgt kttccctttg t                                               21


<210>  12788
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12788
aaacaaagaa rcccaatgta a                                               21


<210>  12789
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12789
cagggatgct yagggcaggt g                                               21


<210>  12790
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12790
ttggtggcac ygatgttagg a                                               21


<210>  12791
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12791
gtgtctagag ygggctggac g                                               21


<210>  12792
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12792
aggatagaaa yctgaacgca t                                               21


<210>  12793
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12793
ccttaactcc ytaactctcc c                                               21


<210>  12794
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12794
agccacagcg mattaatgct t                                               21


<210>  12795
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12795
tcctgggcca ygggtgtctg t                                               21


<210>  12796
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12796
tccagaccct rgtccaagca g                                               21


<210>  12797
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12797
aggtcagtga kcagggtttc c                                               21


<210>  12798
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12798
gattattgat rtcattaggc t                                               21


<210>  12799
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12799
ggggatgcac rggtcaggag g                                               21


<210>  12800
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12800
cccaggcctc yagttcttgt t                                               21


<210>  12801
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12801
ctgtgttgac mactccaggc c                                               21


<210>  12802
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12802
cagtggcata sagaacccac a                                               21


<210>  12803
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12803
tttatacata kgaccatcat t                                               21


<210>  12804
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12804
cagaagatgc kaagtgtttt g                                               21


<210>  12805
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12805
agtgtttagc ytatttttta a                                               21


<210>  12806
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12806
aaaatctaca ytataaccct t                                               21


<210>  12807
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12807
aggggcatac wtgctttcca g                                               21


<210>  12808
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12808
gccacttgaa rgatctacta a                                               21


<210>  12809
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12809
cctgtattat rtggaccaaa c                                               21


<210>  12810
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12810
tcacctgtct yagaacttgc t                                               21


<210>  12811
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12811
aagaaagatg scaaatgtac a                                               21


<210>  12812
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12812
aaaccagtga ygtgggaggg a                                               21


<210>  12813
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12813
atgcattgag rtaagtatcc a                                               21


<210>  12814
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12814
tgaaatacct stttacgtgc t                                               21


<210>  12815
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12815
taatatagat ytcatttgtg t                                               21


<210>  12816
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12816
agttgtagga wgttgctgta t                                               21


<210>  12817
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12817
cgctacccca sagaccctct g                                               21


<210>  12818
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12818
gacttttctc rtagcaaaag a                                               21


<210>  12819
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12819
catacttcac rgagcttaga c                                               21


<210>  12820
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12820
ttggcccttt yagcttcaga t                                               21


<210>  12821
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12821
taattctctg rgtgaaggat t                                               21


<210>  12822
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12822
tatgtccaac rcaccttcaa c                                               21


<210>  12823
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12823
tgtgttgaat kaatgcatgg g                                               21


<210>  12824
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12824
gccttccaga yccaccacag c                                               21


<210>  12825
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12825
cataggccac ygtgtgttta t                                               21


<210>  12826
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12826
ttcagtgtag ycataatttg t                                               21


<210>  12827
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12827
tgtggacaca rtaggaaaga a                                               21


<210>  12828
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12828
tagtatctta ytgaaattcc a                                               21


<210>  12829
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12829
ggtattatac yattttcaga a                                               21


<210>  12830
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12830
gtgaacattc rtgaagtata g                                               21


<210>  12831
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12831
caatgtcatt rtgtagtaca t                                               21


<210>  12832
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12832
agaaaaaaaa rttgtgaggc a                                               21


<210>  12833
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12833
tgaatttagt rctttggatc t                                               21


<210>  12834
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12834
gacaaagaac rttaagtcta t                                               21


<210>  12835
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12835
ttgcattgct rtaggactaa c                                               21


<210>  12836
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12836
aatggcaaaa ygaggacaga a                                               21


<210>  12837
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12837
tttcctagtg stgaggaaca g                                               21


<210>  12838
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12838
ccattttgtc yctgtgtctt g                                               21


<210>  12839
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12839
atgaagaaag rgtgttatgg g                                               21


<210>  12840
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12840
aaattcatca rtacatttgc a                                               21


<210>  12841
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12841
taggtctagg wctgtttctc t                                               21


<210>  12842
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12842
cagtgcctga stcaacatga a                                               21


<210>  12843
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12843
ctacaggtca mctgaatcac c                                               21


<210>  12844
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12844
aattacatac rctaattacc a                                               21


<210>  12845
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12845
cactcagttt ycaaatgtaa g                                               21


<210>  12846
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12846
gatctttcca yttaaaggta g                                               21


<210>  12847
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12847
ctcttctatc ygtacctgcc t                                               21


<210>  12848
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12848
cacagagagg yagggaacat t                                               21


<210>  12849
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12849
ttctagtgcc matggacatc c                                               21


<210>  12850
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12850
taagtaaaat ragaaatcag t                                               21


<210>  12851
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12851
caacacctcc ktaagtttga c                                               21


<210>  12852
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12852
ttagcttcag ygtacccctt t                                               21


<210>  12853
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12853
tgtagcgtgc rtttgagtag c                                               21


<210>  12854
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12854
gataccagat rttaaggcat t                                               21


<210>  12855
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12855
gaatcgggag magcgggcac t                                               21


<210>  12856
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12856
ggtgatagga ytaactccct t                                               21


<210>  12857
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12857
tttcacccgt rtattataga g                                               21


<210>  12858
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12858
ctgtaggctt sagaaaaggc a                                               21


<210>  12859
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12859
tcgttaaaaa wtaggtatgt a                                               21


<210>  12860
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12860
taccatgttt ygtgcagtgt t                                               21


<210>  12861
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12861
gaaggacggg kttagtagta a                                               21


<210>  12862
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12862
aatgtctgga ragtgactgc c                                               21


<210>  12863
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12863
ggatgattgt rgtattaact g                                               21


<210>  12864
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12864
cttccatagc mccgtataag c                                               21


<210>  12865
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12865
gttactctcc ygataatgag t                                               21


<210>  12866
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12866
aacacacaag sgttcacgga a                                               21


<210>  12867
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12867
aagcattata staggaagaa g                                               21


<210>  12868
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12868
gtttcttctt ycatgaccca c                                               21


<210>  12869
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12869
accaaaaaaa yagatatccc t                                               21


<210>  12870
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12870
ctaatgccag ytttttagta a                                               21


<210>  12871
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12871
aaaggactca maaatttcag a                                               21


<210>  12872
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12872
ttgagcaaga yggaggcaaa g                                               21


<210>  12873
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12873
ctgacatcac rttaataatg a                                               21


<210>  12874
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12874
cagtgtcaca rattccaaaa a                                               21


<210>  12875
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12875
tatgaatacg rtcatctcct g                                               21


<210>  12876
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12876
tcagtaatgc ygcaagagac a                                               21


<210>  12877
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12877
tcaactgtac statgacttg t                                               21


<210>  12878
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12878
gaagtggtta mtttaacttg a                                               21


<210>  12879
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12879
ggccaggggg yagtcggact t                                               21


<210>  12880
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12880
tccaaagcat rgtccttatt c                                               21


<210>  12881
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12881
tattagtgcc raatttttcc t                                               21


<210>  12882
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12882
ttaagggctc yttctgtaga g                                               21


<210>  12883
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12883
gatgaggatg yagattcgaa t                                               21


<210>  12884
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12884
tattatctaa raatgtgtta g                                               21


<210>  12885
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12885
cctactatct racaaattgc t                                               21


<210>  12886
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12886
tagcaagcat ygtttagcag a                                               21


<210>  12887
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12887
ctatgagccc rcggtcattt t                                               21


<210>  12888
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12888
ataagaaaaa rgctggaaat g                                               21


<210>  12889
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12889
aatggcctat kattatcatc t                                               21


<210>  12890
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12890
tacattttct yatagattct c                                               21


<210>  12891
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12891
agtgaaaaac raagtcctga a                                               21


<210>  12892
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12892
gtgtaagtcc kattggctga c                                               21


<210>  12893
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12893
tgagtggtta kctgttcttt a                                               21


<210>  12894
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12894
gagtcactaa rgcaggtttt a                                               21


<210>  12895
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12895
tcctggtggc rtcaggcctt g                                               21


<210>  12896
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12896
acctttccct watctcttaa g                                               21


<210>  12897
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12897
aggtgaatca satgagacca a                                               21


<210>  12898
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12898
ttactgacca rttcaagccc a                                               21


<210>  12899
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12899
caatccattc ktgttgtcat t                                               21


<210>  12900
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12900
ctttgagcct ygttagtgag c                                               21


<210>  12901
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12901
ctagtttatg ytcctaaaat a                                               21


<210>  12902
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12902
atgtagtcaa ygatacctat t                                               21


<210>  12903
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12903
taagggacca rtagaagcgt g                                               21


<210>  12904
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12904
tatatgtgct rgaatggttg a                                               21


<210>  12905
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12905
gcatgaaatg rcatagcagt c                                               21


<210>  12906
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12906
atatttgtct rtctttccaa t                                               21


<210>  12907
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12907
agcccaatgt rgctcagata a                                               21


<210>  12908
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12908
gagaacagat rtgtgcagag a                                               21


<210>  12909
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12909
ttactgaact rtgtacaaca t                                               21


<210>  12910
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12910
ttaacacttg maaaaagcta t                                               21


<210>  12911
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12911
ctttccaaat rtaaagtgct g                                               21


<210>  12912
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12912
gcgcaggtac ygcttgggcc a                                               21


<210>  12913
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12913
tcctctcact stggaccagg g                                               21


<210>  12914
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12914
tttctattgg yttttttaat g                                               21


<210>  12915
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12915
taaaggtcta wactctctag g                                               21


<210>  12916
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12916
catagttaaa ktcaatagcc a                                               21


<210>  12917
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12917
tggcttccct yggttgatct t                                               21


<210>  12918
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12918
gtaattgttt yttcatcttc t                                               21


<210>  12919
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12919
atctgtaaat ragaaagcaa t                                               21


<210>  12920
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12920
tgactgacag sacttagtga t                                               21


<210>  12921
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12921
catttgtaac rttcttgcca a                                               21


<210>  12922
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12922
gaacttttat rgattcccat t                                               21


<210>  12923
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12923
tgtagggttc rtattaattg a                                               21


<210>  12924
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12924
ttaatcatag ytatgctcca a                                               21


<210>  12925
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12925
ttcacagttg yatgtcggca g                                               21


<210>  12926
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12926
gatcagtgat rtcttggaaa t                                               21


<210>  12927
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12927
accacttgtc rtattaaata t                                               21


<210>  12928
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12928
cttggttgcc rgagcaaatt a                                               21


<210>  12929
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12929
accatttatc raagacttac c                                               21


<210>  12930
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12930
atctttatcc stagttctgt t                                               21


<210>  12931
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12931
tttccaccag scttacccat c                                               21


<210>  12932
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12932
ggtgcctcct ktgccaagaa c                                               21


<210>  12933
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12933
gtttgtaagc ygtaacatag a                                               21


<210>  12934
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12934
gaattgttta saagtaagac g                                               21


<210>  12935
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12935
tgtgataact magaaacact g                                               21


<210>  12936
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12936
ctttctttca yaggattccc t                                               21


<210>  12937
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12937
attccatcag wgacagcagt a                                               21


<210>  12938
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12938
cctgatggtg wcacttttgg t                                               21


<210>  12939
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12939
tagttatgca rccatcacta c                                               21


<210>  12940
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12940
atgggatggt stagatcatg c                                               21


<210>  12941
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12941
gagaaaattg raaaaagtag g                                               21


<210>  12942
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12942
gttagtctaa yttatgagga t                                               21


<210>  12943
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12943
ttgtctcttt wtcatgtaat a                                               21


<210>  12944
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12944
ttaattttgc ytattgcttt a                                               21


<210>  12945
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12945
ctaagatgtc ygcaaccatt t                                               21


<210>  12946
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12946
taaaacaagg ktacctgtgt a                                               21


<210>  12947
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12947
taattatact wctctttcag t                                               21


<210>  12948
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12948
aggaagtatg raaacaatga a                                               21


<210>  12949
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12949
gagagaaatc yttcaaccag g                                               21


<210>  12950
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12950
ggttttcttt ktctctcagt g                                               21


<210>  12951
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12951
aactaccgtg ktttccccag g                                               21


<210>  12952
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12952
tagttggata sagatggatg t                                               21


<210>  12953
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12953
taacctccag kaaacaatat t                                               21


<210>  12954
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12954
ttatctgcag kagagaaacg t                                               21


<210>  12955
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12955
acctgactgg saaggttctg c                                               21


<210>  12956
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12956
tgagagtgtt rtataaagag g                                               21


<210>  12957
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12957
actcgtaatg yagtcctcaa c                                               21


<210>  12958
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12958
cacactttct rtatggttag g                                               21


<210>  12959
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12959
aatgggaaga ragctaatat a                                               21


<210>  12960
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12960
cttgagtgtt yggtgtagct g                                               21


<210>  12961
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12961
gaatgtagac rccatgcatc c                                               21


<210>  12962
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12962
cagagtcata rttataaaca g                                               21


<210>  12963
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12963
ccaattccac wcttacaatt t                                               21


<210>  12964
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12964
attagaaaga yatatatgtg t                                               21


<210>  12965
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12965
tttagaaaga maaaaactat c                                               21


<210>  12966
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12966
ccactgactt rtcatcattc c                                               21


<210>  12967
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12967
agcatagaaa ygacattttt a                                               21


<210>  12968
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12968
tctggaaaca rctgcttctt a                                               21


<210>  12969
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12969
ttgttcttaa ytgatattct a                                               21


<210>  12970
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12970
atgtagttta ygctgtatac t                                               21


<210>  12971
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12971
ggctaaatag rtactaataa t                                               21


<210>  12972
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12972
gctgtaaatt ygaatcagca c                                               21


<210>  12973
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12973
tgtgctggag rggaaaaatc t                                               21


<210>  12974
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12974
catggagatt raattctagt g                                               21


<210>  12975
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12975
cacatccagg stctatctca c                                               21


<210>  12976
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12976
ctccaagcca ygctgcccag g                                               21


<210>  12977
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12977
tttaatacaa ygctgcaaaa t                                               21


<210>  12978
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12978
ttaaatttct ytccagttgc a                                               21


<210>  12979
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12979
tagatggcta ygcaggacag g                                               21


<210>  12980
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12980
ctgaccaatc rctgttgaag g                                               21


<210>  12981
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12981
ctgctgtcca yatctccaac t                                               21


<210>  12982
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12982
accaatttga kaaatgtaat g                                               21


<210>  12983
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12983
tgctaactac ytcatccttg t                                               21


<210>  12984
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12984
taaatcccag ragaagagct g                                               21


<210>  12985
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12985
ggttaaacaa saggacttgt g                                               21


<210>  12986
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12986
aagtcttggg magataactc a                                               21


<210>  12987
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12987
taaatagttc rttgctcaac t                                               21


<210>  12988
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12988
ttggtttgtc sgatgttgaa a                                               21


<210>  12989
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12989
catgcagaga rctatcagtg a                                               21


<210>  12990
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12990
gagagttacc rattcatttc a                                               21


<210>  12991
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12991
gacccttctt racgatattc t                                               21


<210>  12992
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12992
tgtaaaatat racatagatg t                                               21


<210>  12993
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12993
agcgtttcag mgagaacctc a                                               21


<210>  12994
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12994
taagctgaga ygaggtggag a                                               21


<210>  12995
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12995
ggttagaaac rgcagaatgt a                                               21


<210>  12996
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12996
ctttggcttt stcggcttgc t                                               21


<210>  12997
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12997
ggtccgcttg scggtctgtt c                                               21


<210>  12998
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12998
atgattaaat yaggtatagt a                                               21


<210>  12999
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  12999
ggaacccagc wgagaccaga a                                               21


<210>  13000
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13000
caggtacaca rgtatggcac a                                               21


<210>  13001
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13001
taacagggcc rttcatcgcc c                                               21


<210>  13002
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13002
ggcaggagga ytgcttaagc c                                               21


<210>  13003
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13003
gacattgcat wcagtatgca g                                               21


<210>  13004
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13004
tatgtagatt ygtatcactt c                                               21


<210>  13005
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13005
cttcaaactc yggtgagtga t                                               21


<210>  13006
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13006
gtcattgcca rtgctaacag g                                               21


<210>  13007
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13007
tgtcagcagc ytgactagta t                                               21


<210>  13008
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13008
agatgactta yatgattggt a                                               21


<210>  13009
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13009
atgcttgcag ragttgaaag g                                               21


<210>  13010
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13010
ataaaaatga wctgacctct g                                               21


<210>  13011
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13011
agaggctttc rtatgtggtc t                                               21


<210>  13012
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13012
ttcgccatac raatctacca t                                               21


<210>  13013
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13013
ttgccgtcag raattggctc t                                               21


<210>  13014
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13014
ggggcccttg yagggtgatt c                                               21


<210>  13015
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13015
actcttacac ygctcagggt g                                               21


<210>  13016
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13016
gaagtacata ytgatttcaa g                                               21


<210>  13017
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13017
ttgcaagggt rtagtatttt a                                               21


<210>  13018
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13018
ctcctgctgt ygtaaccacg c                                               21


<210>  13019
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13019
agaacacata raggtataaa t                                               21


<210>  13020
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13020
tttttgagag rtctcctttg a                                               21


<210>  13021
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13021
caaagaaaaa mgtctggttt a                                               21


<210>  13022
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13022
cagagacata ytattttgat t                                               21


<210>  13023
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13023
tctgtattaa mctttgctgt a                                               21


<210>  13024
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13024
cttacgacag yccatatatt t                                               21


<210>  13025
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13025
atttggtctc kactcataat t                                               21


<210>  13026
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13026
atcttcatca yagttccatc t                                               21


<210>  13027
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13027
ttaaactcag yctcttgaag c                                               21


<210>  13028
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13028
gatccttctc rcttttttgg c                                               21


<210>  13029
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13029
acagggtaac rtatacttac a                                               21


<210>  13030
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13030
aggggacaaa rttatttcat a                                               21


<210>  13031
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13031
agatgcttgc ygctatggaa t                                               21


<210>  13032
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13032
gtctattgca yattggtctt t                                               21


<210>  13033
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13033
aattgctctc rtttttgcac t                                               21


<210>  13034
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13034
gcaacttgaa rgtcagtccc t                                               21


<210>  13035
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13035
aaacagtatc rtggagccat c                                               21


<210>  13036
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13036
gagagtgaaa mgcattgtca t                                               21


<210>  13037
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13037
cttggtattt ktatttaatt a                                               21


<210>  13038
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13038
ttgcatgtta rcttgggaac t                                               21


<210>  13039
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13039
ttgctaaaca rcaggcagct t                                               21


<210>  13040
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13040
ggcccgggcc rgggatgtat c                                               21


<210>  13041
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13041
cctcacccac rctactcgcg t                                               21


<210>  13042
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13042
agtcagaata rttctattta a                                               21


<210>  13043
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13043
aacaaaatac mttgtaaaaa a                                               21


<210>  13044
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13044
ggattctgag wgggatctga a                                               21


<210>  13045
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13045
cactggtgca ygaagtcttc t                                               21


<210>  13046
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13046
atcataatca rttggctagt t                                               21


<210>  13047
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13047
caggtgattc raaggtgtga a                                               21


<210>  13048
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13048
ttaagatgaa maagagtgtt g                                               21


<210>  13049
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13049
tgcttgttct kggaaagtaa t                                               21


<210>  13050
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13050
gaaagacgtt stagtggatc t                                               21


<210>  13051
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13051
ggtatgactt yctcccggat t                                               21


<210>  13052
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13052
ctcagagtcc rgaattttca g                                               21


<210>  13053
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13053
tgctatagga kattttcttt t                                               21


<210>  13054
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13054
attagaccac ygacaccaat c                                               21


<210>  13055
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13055
atttagaaag yagctagagg t                                               21


<210>  13056
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13056
tcacactata raatcagact t                                               21


<210>  13057
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13057
tcaagttata rctgtctcaa a                                               21


<210>  13058
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13058
atttgttata ygattacctt t                                               21


<210>  13059
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13059
tggagttcac ytaatctcag c                                               21


<210>  13060
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13060
gaaaatccat rattaaaagc t                                               21


<210>  13061
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13061
tgccagaaag yccatgaggt t                                               21


<210>  13062
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13062
ttgagttatt yttttgacag g                                               21


<210>  13063
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13063
ggcatacttt rtggaaaaat g                                               21


<210>  13064
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13064
taaggtggta yctgattcac a                                               21


<210>  13065
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13065
aattttagta wctccagatt t                                               21


<210>  13066
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13066
actgtataac ygactcatag g                                               21


<210>  13067
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13067
aaatatatac rttagttcca g                                               21


<210>  13068
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13068
gttatcatct rtataatgca a                                               21


<210>  13069
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13069
acaagcagct rggtttgaga t                                               21


<210>  13070
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13070
gtaatattcc ytctactttg g                                               21


<210>  13071
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13071
tttaaagatc wgatggttta c                                               21


<210>  13072
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13072
atacagtgtt rtcagaaaga a                                               21


<210>  13073
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13073
catcttcctc kctgttcgtg t                                               21


<210>  13074
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13074
cagttttgta yaacattttg c                                               21


<210>  13075
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13075
tttcatggac yaggcccagg g                                               21


<210>  13076
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13076
tcctttaagt yttactgatt a                                               21


<210>  13077
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13077
tctttcccta ygatatgtta a                                               21


<210>  13078
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13078
tggatagata mcagagttaa t                                               21


<210>  13079
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13079
gtaaactaac rtgccattac c                                               21


<210>  13080
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13080
gaaatgaaga rtaccttctc a                                               21


<210>  13081
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13081
ttgttaatag maagtgattg t                                               21


<210>  13082
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13082
tatgtcaatg mtcatttata a                                               21


<210>  13083
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13083
cagttcaaat wctaagtaat t                                               21


<210>  13084
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13084
ttatatatga ygatttccct c                                               21


<210>  13085
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13085
ctatccgtaa matgctagtt t                                               21


<210>  13086
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13086
ctagagtaca yggcaatatc a                                               21


<210>  13087
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13087
tttgaaagac sttcctggag g                                               21


<210>  13088
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13088
attttattag yttcaaatgc c                                               21


<210>  13089
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13089
cttctgcaag yccttgggca t                                               21


<210>  13090
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13090
tctatctatt yggtctttct a                                               21


<210>  13091
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13091
gagacataaa rtaagagtgg c                                               21


<210>  13092
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13092
gtgccacaca ygagctcagg t                                               21


<210>  13093
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13093
cataaattca mgagtgggaa t                                               21


<210>  13094
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13094
tgaggtgctg yctttgaaga a                                               21


<210>  13095
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13095
tgtttggttg mccccatttt t                                               21


<210>  13096
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13096
cacacttcta wgccttccag c                                               21


<210>  13097
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13097
cctattttga rtccactgga a                                               21


<210>  13098
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13098
ctaatctcta rtaagaagct g                                               21


<210>  13099
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13099
tccagctagc yatccacaaa c                                               21


<210>  13100
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13100
tggaactgtt ygctgtgcaa g                                               21


<210>  13101
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13101
tatcaaaaac rtaattctgc a                                               21


<210>  13102
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13102
cttctttaac rtgcacaaca a                                               21


<210>  13103
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13103
acccagatgc ygaagggaat c                                               21


<210>  13104
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13104
ttacagatta yggcttctat c                                               21


<210>  13105
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13105
tctttcttac rctttgaatt t                                               21


<210>  13106
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13106
ggacttcttc rggatgatct c                                               21


<210>  13107
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13107
gttgttatca ygaccatttg a                                               21


<210>  13108
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13108
tgtaataggc magagttgag t                                               21


<210>  13109
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13109
ttgcaaggat rtcagggaac t                                               21


<210>  13110
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13110
tgctcaagtg waatcgacaa c                                               21


<210>  13111
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13111
gactgttgat rtggtgactc t                                               21


<210>  13112
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13112
atcagggtac rggaacaccc a                                               21


<210>  13113
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13113
tttaacctta maattacaag a                                               21


<210>  13114
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13114
cttatctcag ygatttcatc g                                               21


<210>  13115
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13115
actctatttt rcaaactgat t                                               21


<210>  13116
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13116
ttcgatttcc sacatttttt c                                               21


<210>  13117
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13117
tgttatttcc rtcgttttat t                                               21


<210>  13118
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13118
aaaggcaagc maggcctaca t                                               21


<210>  13119
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13119
aaaaggagtc rgcaaatgat c                                               21


<210>  13120
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13120
actgacccct yatgtgtccc a                                               21


<210>  13121
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13121
ctgaagtgta ygaccaagac a                                               21


<210>  13122
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13122
tggccttgct yggcaggaac a                                               21


<210>  13123
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13123
atgccctgga waaatgatac c                                               21


<210>  13124
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13124
gttgcagaat sctatgcaaa a                                               21


<210>  13125
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13125
cacggggcca ygcgtgctct t                                               21


<210>  13126
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13126
tgaatagaga kcctgggcct c                                               21


<210>  13127
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13127
ctatttccta saactgcttc c                                               21


<210>  13128
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13128
cagcctcagg wgaatgaaaa a                                               21


<210>  13129
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13129
agagggcccc rgctcaaaga a                                               21


<210>  13130
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13130
ctcgcctaac matatttgtc c                                               21


<210>  13131
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13131
ttcatctttc rtttctaatt g                                               21


<210>  13132
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13132
ctcagaaatt saagtgatat a                                               21


<210>  13133
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13133
tatggtactc yggtgacccc a                                               21


<210>  13134
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13134
tcatggatta saaagccaaa t                                               21


<210>  13135
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13135
actccaaacc ragacagttc a                                               21


<210>  13136
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13136
catgagaggt rctaattagg c                                               21


<210>  13137
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13137
ttcattgtta rggatgttag a                                               21


<210>  13138
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13138
tcctggctcc rtgaactcag g                                               21


<210>  13139
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13139
gtgttctttc yaatttttga g                                               21


<210>  13140
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13140
tcccataaga yggatttctt c                                               21


<210>  13141
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13141
aggagctgct rtgagtagtg g                                               21


<210>  13142
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13142
tacggtgcct yagttaatcc c                                               21


<210>  13143
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13143
ggagacttcc yttttgacaa t                                               21


<210>  13144
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13144
ttttggcaga rcatagaaaa t                                               21


<210>  13145
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13145
cataggactt kcttttagta g                                               21


<210>  13146
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13146
taaacccgga rcctccaggt g                                               21


<210>  13147
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13147
agcccagtgg wcattatgct t                                               21


<210>  13148
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13148
aaatacagac rgttcttgaa c                                               21


<210>  13149
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13149
tataaatgta ygtttattat t                                               21


<210>  13150
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13150
tacatgccca ytcatacaca c                                               21


<210>  13151
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13151
acaaatgacc wtgggcgtcc a                                               21


<210>  13152
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13152
gacctcaccc rcccagaagt t                                               21


<210>  13153
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13153
atatgttcct sgttgggttt a                                               21


<210>  13154
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13154
gtgggactca kcgaacactg g                                               21


<210>  13155
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13155
aactttttgg rtcatcaaga a                                               21


<210>  13156
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13156
cagccctcca mccgactcat g                                               21


<210>  13157
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13157
agtaaaatga rcacaacaag a                                               21


<210>  13158
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13158
aacaccctca ytgggcagac t                                               21


<210>  13159
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13159
ttccgtgcaa yagaacgtga c                                               21


<210>  13160
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13160
ggctggaggt ygaattggct g                                               21


<210>  13161
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13161
aaggggtcca ytccaacctt c                                               21


<210>  13162
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13162
gaactcaacc rcagagacac c                                               21


<210>  13163
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13163
gctcctactc rgcaacatca g                                               21


<210>  13164
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13164
tgaattggaa rcacaggtct t                                               21


<210>  13165
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13165
gagctaggtt scagaagatg a                                               21


<210>  13166
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13166
gttttcacac rgacagggta t                                               21


<210>  13167
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13167
cagagtataa yggaatattt g                                               21


<210>  13168
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13168
tcttggtgag ygcacagctc a                                               21


<210>  13169
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13169
ttgagatggc ktaacaatct t                                               21


<210>  13170
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13170
ctccggacct yggctgcaga g                                               21


<210>  13171
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13171
acaaaatatc kccatcatga a                                               21


<210>  13172
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13172
gtttggagca ygggccattg c                                               21


<210>  13173
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13173
tacttaattg scactttttc t                                               21


<210>  13174
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13174
agcaagtgat ytctagcatc t                                               21


<210>  13175
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13175
aatttaatga rcacccttga t                                               21


<210>  13176
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13176
caattgacag wtgacttccc c                                               21


<210>  13177
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13177
agcctttatt ycacttccag g                                               21


<210>  13178
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13178
gcaaggctgt yggagggatg c                                               21


<210>  13179
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13179
gaaagggctt ytcccacttg g                                               21


<210>  13180
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13180
cagtgatttt rtctggactg a                                               21


<210>  13181
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13181
tttcccatat rttgggctga t                                               21


<210>  13182
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13182
tgtgatctct scaagtctct a                                               21


<210>  13183
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13183
agtgaaaccc rtcatttcag c                                               21


<210>  13184
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13184
tagctgagaa ygagtgcatg a                                               21


<210>  13185
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13185
agagagatga stgagggaaa g                                               21


<210>  13186
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13186
aaagaaaaat rttgtattat t                                               21


<210>  13187
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13187
tggaaagtgg mccaggatca a                                               21


<210>  13188
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13188
atcattgaac katttttttt c                                               21


<210>  13189
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13189
gtgtggagcc maagagggga c                                               21


<210>  13190
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13190
aggatgggag kgtcctcata a                                               21


<210>  13191
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13191
atggctcacc rcctgaatgg c                                               21


<210>  13192
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13192
cccaggacga ygtcttcccg a                                               21


<210>  13193
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13193
ggttagacag sgaatttgaa g                                               21


<210>  13194
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13194
aattaatcct yttctgcctt c                                               21


<210>  13195
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13195
agcctgtgga kgtaggatgg t                                               21


<210>  13196
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13196
atctgaaatc rtggtctgtt g                                               21


<210>  13197
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13197
tgctgagatg saaatcgctg a                                               21


<210>  13198
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13198
ctggatctgc ygtatccacc t                                               21


<210>  13199
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13199
accactgatt kggatataaa t                                               21


<210>  13200
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13200
aaacccacca saaaaataca t                                               21


<210>  13201
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13201
ggcctatgga ytgcagggca g                                               21


<210>  13202
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13202
tcctctttca scctcaacct g                                               21


<210>  13203
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13203
aaggctgtgc ygtcgttcac c                                               21


<210>  13204
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13204
gagatgctgc stctgcctga c                                               21


<210>  13205
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13205
cttcacctgc rttccctctg t                                               21


<210>  13206
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13206
caggagaggc ygagggaaga g                                               21


<210>  13207
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13207
ccacccgata ytgctgcatg t                                               21


<210>  13208
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13208
aattagacaa yctgcgtagt g                                               21


<210>  13209
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13209
ccttcgattc rggtgtggat g                                               21


<210>  13210
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13210
tctcattttc rtcttctgat g                                               21


<210>  13211
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13211
catggaaacc rgcaaaaaac g                                               21


<210>  13212
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13212
gggcaagggt ygtacctgaa t                                               21


<210>  13213
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13213
cttaaatgca sgtgagcttg g                                               21


<210>  13214
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13214
tcatcctccc wctgaactca t                                               21


<210>  13215
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13215
aaattacttg saagaaattc t                                               21


<210>  13216
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13216
atggaggcac ratacaatct g                                               21


<210>  13217
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13217
tattcccaac ragaagcttc a                                               21


<210>  13218
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13218
tggatgaggg yggaaggaag g                                               21


<210>  13219
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13219
tttgtggcag ktgtagagat t                                               21


<210>  13220
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13220
tgactcagtg rcggaaccag g                                               21


<210>  13221
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13221
accacccaga ygtcagtttt t                                               21


<210>  13222
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13222
caggaatatc ygcctcttcc c                                               21


<210>  13223
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13223
acaagtggag mgcaataaac a                                               21


<210>  13224
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13224
aactgtactt yagcttggtc a                                               21


<210>  13225
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13225
agagtgccag sgtcctagga a                                               21


<210>  13226
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13226
ttttgaaaca rtgttgctca g                                               21


<210>  13227
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13227
gagcacacag ygttagataa t                                               21


<210>  13228
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13228
gcatgcctta kggctgagga t                                               21


<210>  13229
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13229
tgacagtgga rtggctgttc t                                               21


<210>  13230
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13230
tacatgagag yaggaacccc a                                               21


<210>  13231
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13231
caggaagcag scagcaggtg g                                               21


<210>  13232
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13232
tcagattctg raggacaaga t                                               21


<210>  13233
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13233
gctcaaaaac rtaaaacacc a                                               21


<210>  13234
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13234
taagtgttgg ycagatgtct a                                               21


<210>  13235
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13235
gcttttctat rtatttgcaa c                                               21


<210>  13236
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13236
ccttcaggag yattagcctg g                                               21


<210>  13237
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13237
gaccagtgcc rtgtaaatgt c                                               21


<210>  13238
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13238
gagaataaag ragacttgcc t                                               21


<210>  13239
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13239
acaaaagata yaaacaggca a                                               21


<210>  13240
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13240
ctctgatgta rttggtatgg t                                               21


<210>  13241
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13241
tttggtttaa ygagggatag g                                               21


<210>  13242
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13242
gtctcatgga yggggacaat g                                               21


<210>  13243
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13243
tgatatgatg ytatgttatg t                                               21


<210>  13244
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13244
tgccaccgaa kggtattaag c                                               21


<210>  13245
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13245
agcagtgcca ycagactcct c                                               21


<210>  13246
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13246
ggcagcttaa mggggatgtg t                                               21


<210>  13247
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13247
ggtgtctctg rcccaaatag c                                               21


<210>  13248
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13248
gtatacataa ktttaaagaa a                                               21


<210>  13249
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13249
aatgccagga mtgattcata g                                               21


<210>  13250
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13250
gtaaaacacc ygcgtcaggg t                                               21


<210>  13251
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13251
cccttttgaa yacacccatg t                                               21


<210>  13252
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13252
tctcaggaac ycccttggct c                                               21


<210>  13253
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13253
ctttactgag kcttgatcag a                                               21


<210>  13254
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13254
gttaactggt rcccattgca c                                               21


<210>  13255
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13255
aaaataaaac rcaacagcta g                                               21


<210>  13256
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13256
gtcactgagc ygcagcaggc g                                               21


<210>  13257
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13257
gaactggaaa rctgggaata t                                               21


<210>  13258
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13258
accaaaagag rtcagcctca g                                               21


<210>  13259
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13259
gcccatcttc rtggatttaa g                                               21


<210>  13260
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13260
atggaagagt rtctagttct a                                               21


<210>  13261
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13261
gggaagggac ygcatagttg g                                               21


<210>  13262
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13262
tccccttcgg raacagagca a                                               21


<210>  13263
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13263
agtccacagg ygctaccctg g                                               21


<210>  13264
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13264
cgggctagtg yatcctcctc a                                               21


<210>  13265
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13265
agtaaacgat yttatccaca a                                               21


<210>  13266
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13266
atagagaaca ycgttgtttt a                                               21


<210>  13267
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13267
tgagaatgta magcacacaa c                                               21


<210>  13268
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13268
tgggaagtga ytggggaagg g                                               21


<210>  13269
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13269
cctggccagc rtggaacgca a                                               21


<210>  13270
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13270
agaaacagac ytgctcagat c                                               21


<210>  13271
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13271
tactaatagg ygattgctgt a                                               21


<210>  13272
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13272
ctggcacggt ygggaaaggt c                                               21


<210>  13273
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13273
cctagagttg yaaaggcctc a                                               21


<210>  13274
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13274
cgattattca rtaaaggaat g                                               21


<210>  13275
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13275
tttcaagcct ytctattggc c                                               21


<210>  13276
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13276
gactaaatct yaagtgcatg c                                               21


<210>  13277
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13277
ctaaactgat mtctaagtga g                                               21


<210>  13278
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13278
agctgttttt ycctgggtca c                                               21


<210>  13279
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13279
cctcacaagc rggtgtctag g                                               21


<210>  13280
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13280
ctcacttttc rtctgttcct t                                               21


<210>  13281
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13281
tgtttgaagg mgggttgcta a                                               21


<210>  13282
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13282
gagggtttaa raaacagctg c                                               21


<210>  13283
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13283
attgagctcc yggatcttca a                                               21


<210>  13284
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13284
aaatatacat saatactggc t                                               21


<210>  13285
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13285
gacactgaaa mctggaaagg a                                               21


<210>  13286
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13286
gccaatccta ygaaataaaa c                                               21


<210>  13287
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13287
gctatatttc ytcctctaca a                                               21


<210>  13288
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13288
agactagtac rtcctctaaa g                                               21


<210>  13289
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13289
gttacaataa raacacttgg a                                               21


<210>  13290
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13290
catattgaag ytctacagtt a                                               21


<210>  13291
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13291
gaaggataac raacaatagc t                                               21


<210>  13292
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13292
agaaaatgta rtatgacaat c                                               21


<210>  13293
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13293
attttaactg rgatattcct g                                               21


<210>  13294
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13294
aagtgattgg yattattgct t                                               21


<210>  13295
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13295
taattgttag yctcagggaa a                                               21


<210>  13296
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13296
tgaaaagaac ktggggtcta g                                               21


<210>  13297
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13297
cttaaaattc rgggtctttg a                                               21


<210>  13298
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13298
tagcagttag ytgaaacaac a                                               21


<210>  13299
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13299
ataatttggt rtaagtgtgg a                                               21


<210>  13300
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13300
caccatctgc rcaactgctt t                                               21


<210>  13301
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13301
gttttttgaa ygtggggaaa t                                               21


<210>  13302
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13302
agaagatgac rctcctgatt t                                               21


<210>  13303
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13303
ccacagaatg ytaccctgac a                                               21


<210>  13304
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13304
gagtcctaat ktgcaccagg t                                               21


<210>  13305
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13305
agtgacatgg sattcaaaaa a                                               21


<210>  13306
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13306
gcttactatt ygaaagactg t                                               21


<210>  13307
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13307
cctcacattc ygcaaccctg a                                               21


<210>  13308
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13308
tatactcatc rtctttctag g                                               21


<210>  13309
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13309
atctctactc ycttgcctgg c                                               21


<210>  13310
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13310
ccagaagggt ytgtctaaag c                                               21


<210>  13311
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13311
atgactgaat rttagggatg a                                               21


<210>  13312
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13312
taacacagaa maaatgcacc a                                               21


<210>  13313
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13313
ggtgcttcca yaaagggtgg a                                               21


<210>  13314
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13314
ggctaatgag rctgaccctg c                                               21


<210>  13315
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13315
caagaagcag ratgcatcaa a                                               21


<210>  13316
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13316
ctgctcaaca rggaggagaa t                                               21


<210>  13317
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13317
tatttaatac sctgcttttg c                                               21


<210>  13318
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13318
tgagctgtcc rgagtaaaaa a                                               21


<210>  13319
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13319
tgactatcca yttatcttta c                                               21


<210>  13320
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13320
gtggagcctg rgatggcctc a                                               21


<210>  13321
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13321
ccgggtcagc ycattagggt c                                               21


<210>  13322
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13322
tcccagccca ygaagatcgg c                                               21


<210>  13323
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13323
ccatgttgag rtcctagctg a                                               21


<210>  13324
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13324
aaccacaagg ycttctgctc a                                               21


<210>  13325
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13325
tagtgatttc rttatgacac a                                               21


<210>  13326
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13326
gtcaaagaga ygccaagatt a                                               21


<210>  13327
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13327
tcatagcctt ygcctctgaa c                                               21


<210>  13328
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13328
caaaaactca yacacgaagc a                                               21


<210>  13329
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13329
caccaaaaaa yggatcagga g                                               21


<210>  13330
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13330
cagtcactga ytttcattta a                                               21


<210>  13331
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13331
tcactaacat kggcagtcat a                                               21


<210>  13332
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13332
ctaatgttat yagctatacc c                                               21


<210>  13333
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13333
agcatcctgt rtcttaaaag c                                               21


<210>  13334
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13334
attagaaaca rattaggcaa a                                               21


<210>  13335
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13335
tgcctgagaa ytggagcgaa g                                               21


<210>  13336
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13336
tctcatcagg maagaaagaa g                                               21


<210>  13337
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13337
aacatggtat ktgaggcaaa t                                               21


<210>  13338
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13338
ctgcggtatg rggttatgtt t                                               21


<210>  13339
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13339
gccctgtgtc ygcgtcaagc a                                               21


<210>  13340
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13340
ggatggattc rgatttgcct c                                               21


<210>  13341
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13341
gccaccttca scaccctttc c                                               21


<210>  13342
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13342
ggccaccttc ygctgggtag c                                               21


<210>  13343
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13343
ctcctgagtc yttactgata c                                               21


<210>  13344
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13344
tctatcttgc rgggtctgat g                                               21


<210>  13345
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13345
gcaactgaac rtaactgttt t                                               21


<210>  13346
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13346
atcagtgata mtgcgttcta c                                               21


<210>  13347
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13347
gaaaatggaa mttgtcttta c                                               21


<210>  13348
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13348
atgactgtgt wttttgaaat c                                               21


<210>  13349
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13349
gccattggtc kttctcctct c                                               21


<210>  13350
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13350
ggcctaagca ygcatttttt c                                               21


<210>  13351
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13351
gacaaagtga rgtaggtaaa a                                               21


<210>  13352
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13352
ggtagatcca yagaagacag g                                               21


<210>  13353
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13353
aggtgaataa wctgacatca c                                               21


<210>  13354
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13354
ttttctgata mtgccttgaa t                                               21


<210>  13355
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13355
ccagcaaaac maacagggag c                                               21


<210>  13356
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13356
ccctaagatg wtcctaagaa g                                               21


<210>  13357
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13357
tttcccaatc ytaagcagcc c                                               21


<210>  13358
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13358
cgtatgctct saaagctagg a                                               21


<210>  13359
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13359
ttacaatcaa ygatattgag a                                               21


<210>  13360
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13360
gcagctttcc matcacttac t                                               21


<210>  13361
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13361
cactgctgct kttccataga a                                               21


<210>  13362
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13362
agagctccaa yttttagaaa c                                               21


<210>  13363
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13363
tagagagctc racaccactc c                                               21


<210>  13364
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13364
agagcagtgc rccagggaag g                                               21


<210>  13365
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13365
actgtacaga kaagatgcct g                                               21


<210>  13366
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13366
caaccacatc rcccagaatg t                                               21


<210>  13367
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13367
tggcagttct yggcctctgc t                                               21


<210>  13368
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13368
ttgattccca rgcgtgggtc t                                               21


<210>  13369
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13369
ttcatctgta ytgattgact a                                               21


<210>  13370
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13370
gcttccttgt yggttccatt t                                               21


<210>  13371
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13371
catcctaaca ratcttgcca g                                               21


<210>  13372
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13372
acatggtaac ycagcctggc t                                               21


<210>  13373
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13373
gaatataaga yggagtcatt a                                               21


<210>  13374
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13374
catgtatttt yggaattacg t                                               21


<210>  13375
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13375
ataagggtgc kagaccaaga t                                               21


<210>  13376
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13376
ttataaaacc rgttgcactc c                                               21


<210>  13377
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13377
tcctcattca raattgttat t                                               21


<210>  13378
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13378
ctgtattgta scaagcacta t                                               21


<210>  13379
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13379
gttgccagca ytcagagcct c                                               21


<210>  13380
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13380
attatccagg yaagagtatg g                                               21


<210>  13381
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13381
acgtatgtgc mtgcagacaa a                                               21


<210>  13382
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13382
tagtatgtac mtagttttga c                                               21


<210>  13383
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13383
attttaatca rtgattgcta g                                               21


<210>  13384
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13384
ctgaagacca ycctgttgct a                                               21


<210>  13385
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13385
gtcaggtact rtccccttcc g                                               21


<210>  13386
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13386
tggttgaaac ytctagtaga c                                               21


<210>  13387
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13387
tacagggtat rggtcgagct g                                               21


<210>  13388
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13388
cagcatcccg yaggatacct t                                               21


<210>  13389
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13389
gtgataaaaa saacatctta a                                               21


<210>  13390
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13390
tcagtatata yagattttgc t                                               21


<210>  13391
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13391
taatgatagc raaaatgatg a                                               21


<210>  13392
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13392
acacagtgta yattttaaac t                                               21


<210>  13393
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13393
atagcaggtg ytcaggaact a                                               21


<210>  13394
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13394
gatgctgtga ktaataaaat g                                               21


<210>  13395
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13395
cctgcaaccc rttttcacac a                                               21


<210>  13396
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13396
aatacctcta yactttccca c                                               21


<210>  13397
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13397
aaggaccatc ktccagtgtc t                                               21


<210>  13398
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13398
cactaaattg rcagggcctg g                                               21


<210>  13399
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13399
tcttcacatc ratatggtaa a                                               21


<210>  13400
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13400
agtgtatgca ygagcaggcc a                                               21


<210>  13401
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13401
aagctacaga wccaccagcg a                                               21


<210>  13402
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13402
acaagagcaa kctgaccatg g                                               21


<210>  13403
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13403
gactcccaca ygccattttt t                                               21


<210>  13404
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13404
agttatgcgt rttctttttc c                                               21


<210>  13405
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13405
taagacctgc sctggccagt c                                               21


<210>  13406
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13406
catgacacag rcccagaggc a                                               21


<210>  13407
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13407
cctttgccag rgcctggaag c                                               21


<210>  13408
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13408
tctttatatc yggacaagag a                                               21


<210>  13409
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13409
actccacctc rgaattcaag t                                               21


<210>  13410
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13410
aaacagagtc rgctttagca t                                               21


<210>  13411
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13411
tgagaagaaa kctcaaagag g                                               21


<210>  13412
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13412
ggatttaggt rcagttctac t                                               21


<210>  13413
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13413
tacgacacta ycattatgtt c                                               21


<210>  13414
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13414
actccagcac yggggaaagt g                                               21


<210>  13415
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13415
ccctcgtgca satattcact c                                               21


<210>  13416
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13416
ctgttttctg yaggagggac c                                               21


<210>  13417
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13417
acaagttaat mcctccatga a                                               21


<210>  13418
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13418
acagaagaga mgcacttgtg c                                               21


<210>  13419
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13419
gatttcacaa rgacaggcat c                                               21


<210>  13420
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13420
taccctctca rtttggaagt t                                               21


<210>  13421
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13421
gaaaagacta yatggaagag a                                               21


<210>  13422
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13422
ttggggtgca yttgagtcac c                                               21


<210>  13423
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13423
tcctccttta ytctccatag a                                               21


<210>  13424
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13424
aaagaaatag ygtctgagat c                                               21


<210>  13425
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13425
tccaaacatt kttccaaact t                                               21


<210>  13426
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13426
tagtaccgct macttaatcc c                                               21


<210>  13427
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13427
gaacagatgg kagtactaaa g                                               21


<210>  13428
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13428
caaggaccaa rgtagtgaag c                                               21


<210>  13429
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13429
gaaaggggaa wcacccatcc t                                               21


<210>  13430
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13430
tctattggct mccagcacca g                                               21


<210>  13431
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13431
aaaaatgcaa rtcctaaaac a                                               21


<210>  13432
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13432
catttctaga sacttcctgt t                                               21


<210>  13433
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13433
cccttacaca yacttccctt t                                               21


<210>  13434
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13434
tgcaggtttt ygctcttaaa c                                               21


<210>  13435
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13435
tgggaccaag ytgagtacca c                                               21


<210>  13436
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13436
gaatcgattc mcaatttatg a                                               21


<210>  13437
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13437
gatggttggc rtggagcagc t                                               21


<210>  13438
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13438
ctgacagaga ygatgttatt t                                               21


<210>  13439
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13439
tctcctggag kcaagtgctt c                                               21


<210>  13440
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13440
ggttctcaca stgtgccacc c                                               21


<210>  13441
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13441
tcccggctca scacagacag g                                               21


<210>  13442
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13442
ttgaccttct staggtgctc g                                               21


<210>  13443
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13443
gtaaacgaag sattttgttt t                                               21


<210>  13444
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13444
cttaatgtca wctagacaca t                                               21


<210>  13445
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13445
caccagtcat yggagtgagg g                                               21


<210>  13446
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13446
atataatttt ygcaataatc c                                               21


<210>  13447
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13447
tttgtctatt statcatttt c                                               21


<210>  13448
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13448
caagtctgct rggcaaggtc c                                               21


<210>  13449
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13449
tggcttttgg yatgaaagga a                                               21


<210>  13450
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13450
ctgctgactt yggtggcctg a                                               21


<210>  13451
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13451
atcattcata stggctgctg c                                               21


<210>  13452
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13452
cacatctaac rcagaaggaa a                                               21


<210>  13453
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13453
aataaaagtc kgatcgtttt g                                               21


<210>  13454
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13454
ctctccatta yactctggag a                                               21


<210>  13455
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13455
atctatacca ygctacccag g                                               21


<210>  13456
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13456
aatgcacaag rgttgaaggg a                                               21


<210>  13457
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13457
tgtacatgtc racgatcttc t                                               21


<210>  13458
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13458
tccatcaaac rcggggtcaa g                                               21


<210>  13459
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13459
ttatgcctga mttataatcg c                                               21


<210>  13460
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13460
tacaagatcg ycctcaaacc c                                               21


<210>  13461
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13461
tgatgcttct saagtctcca t                                               21


<210>  13462
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13462
catcacagag mtgacatgtt a                                               21


<210>  13463
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13463
gtgggtatac mgaagagaat t                                               21


<210>  13464
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13464
ccgtcttggg stagtacgta c                                               21


<210>  13465
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13465
agtggtaata wgaaaaatac c                                               21


<210>  13466
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13466
gaagattttc ygctttattt t                                               21


<210>  13467
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13467
acaagcttat rtgacaaatg g                                               21


<210>  13468
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13468
cataagcccc yataatttgt g                                               21


<210>  13469
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13469
agatgtgctg ktatcactgg g                                               21


<210>  13470
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13470
ttcagcttta wcttttgcca t                                               21


<210>  13471
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13471
aattgcatgt kggaaacact g                                               21


<210>  13472
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13472
caagatcaac mgttttccca a                                               21


<210>  13473
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13473
ccacattgcc rtgctaactg g                                               21


<210>  13474
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13474
tacactttat raatgaaatg g                                               21


<210>  13475
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13475
cagcataata sgaagacctt g                                               21


<210>  13476
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13476
aggcaggtga ycccttagag a                                               21


<210>  13477
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13477
acaagtaaaa sagaaaactc a                                               21


<210>  13478
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13478
cttcactatc wgataaaatg t                                               21


<210>  13479
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13479
tgtggaacca yggcaccaac t                                               21


<210>  13480
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13480
ggcctgttta maatatttac t                                               21


<210>  13481
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13481
agctcaagag rctccaagac a                                               21


<210>  13482
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13482
acagctcaga rggaggtgag c                                               21


<210>  13483
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13483
aagcaccctg ygaccgtgtg g                                               21


<210>  13484
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13484
ggcccaactt scctattaga a                                               21


<210>  13485
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13485
ataaaaaggt rtttggatgc c                                               21


<210>  13486
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13486
cacagattat ygaccaccta c                                               21


<210>  13487
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13487
gcagaagtgg ratgtttcag a                                               21


<210>  13488
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13488
atcgtagatt sattgatttt g                                               21


<210>  13489
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13489
tctatgacaa sgtactcttc t                                               21


<210>  13490
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13490
tagatttgct sttttgctct t                                               21


<210>  13491
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13491
tgcgctccca rtgcctacta t                                               21


<210>  13492
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13492
tagtaatgcc rgcttttcta c                                               21


<210>  13493
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13493
accctagaag wctttcaatt t                                               21


<210>  13494
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13494
gtttttgtag rtattatagg a                                               21


<210>  13495
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13495
tgtacctatt ycttaaggct a                                               21


<210>  13496
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13496
ctcaaaatgt kattgagact c                                               21


<210>  13497
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13497
ttaattatcc rtatttatag c                                               21


<210>  13498
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13498
cagggaatct sttcatgaac t                                               21


<210>  13499
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13499
ttgaagatgc ytgtcaatga a                                               21


<210>  13500
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13500
tttggcaacc wagtccctca a                                               21


<210>  13501
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13501
tgtatcacat scactgaaga c                                               21


<210>  13502
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13502
ataatacata ygaaaaagga c                                               21


<210>  13503
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13503
atatctggcc ragagggatg a                                               21


<210>  13504
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13504
aatctattgg yatccacagg a                                               21


<210>  13505
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13505
ggaaattcca rttccttctt t                                               21


<210>  13506
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13506
agacacacac rgtaaccaag t                                               21


<210>  13507
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13507
aggcggggaa kggtattcca a                                               21


<210>  13508
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13508
cagagtcgca saggatcggg g                                               21


<210>  13509
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13509
ggaagtgccc rttctcagtg t                                               21


<210>  13510
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13510
cagatgacgt yttagtttta g                                               21


<210>  13511
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13511
ctcgacttca mtggggataa g                                               21


<210>  13512
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13512
aactggttag ygtttgcaat c                                               21


<210>  13513
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13513
tagaggtcag yggcactggc g                                               21


<210>  13514
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13514
attaagcgcc rgtgttctga g                                               21


<210>  13515
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13515
cagacttaca rgcacagggc c                                               21


<210>  13516
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13516
tagatcagcc staaatgcct t                                               21


<210>  13517
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13517
atgtggtcaa rtggattttt c                                               21


<210>  13518
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13518
tttctccaac rtctatgtca a                                               21


<210>  13519
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13519
tacagcagac raagtgctaa a                                               21


<210>  13520
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13520
gtgctgagca rgtggaccca a                                               21


<210>  13521
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13521
tttcactgct saagagtagt t                                               21


<210>  13522
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13522
aggcattttt scattctgaa t                                               21


<210>  13523
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13523
gggaattttc yctggagagt g                                               21


<210>  13524
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13524
gggagcctca ygttgtgtgt a                                               21


<210>  13525
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13525
gcagtctcca kgtcctcgtt t                                               21


<210>  13526
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13526
gcccagtata ratcatccct c                                               21


<210>  13527
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13527
catttgccct rgaaaacagg a                                               21


<210>  13528
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13528
accctgtttt kgttcctcca t                                               21


<210>  13529
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13529
cttcttcacc rtagtacttt t                                               21


<210>  13530
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13530
ccgggagtct macctctgcc t                                               21


<210>  13531
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13531
tgctagggac ygtgtctagc t                                               21


<210>  13532
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13532
gatacgatga yggacactgc a                                               21


<210>  13533
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13533
cggctcttac rctgttgcca a                                               21


<210>  13534
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13534
aaattatcac kcctctctct g                                               21


<210>  13535
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13535
cctcaaggtc wgggtccact t                                               21


<210>  13536
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13536
tacagttgta yacaggttta c                                               21


<210>  13537
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13537
cttggtttgc magctagacc t                                               21


<210>  13538
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13538
aacaaaaaga ygaccatgag a                                               21


<210>  13539
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13539
tttggtccta mttagaaagg c                                               21


<210>  13540
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13540
gagttagtac sgtgcgagga g                                               21


<210>  13541
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13541
taccatggcc rctctgacct g                                               21


<210>  13542
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13542
tcaataagtc rccctacaag g                                               21


<210>  13543
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13543
tgtatgtgtc yatgtggtga c                                               21


<210>  13544
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13544
accctctggc rgccttggcc c                                               21


<210>  13545
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13545
cccagatgct rttggcagcc a                                               21


<210>  13546
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13546
gagtgttttg rttgccaaca a                                               21


<210>  13547
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13547
gatcagactc rattctattt t                                               21


<210>  13548
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13548
aagaaaaggg ygtttatagc t                                               21


<210>  13549
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13549
tttgtgaact rtaaagcatt g                                               21


<210>  13550
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13550
ccttgagacc yttctgaaga c                                               21


<210>  13551
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13551
ctgcacatgc rccctgagct t                                               21


<210>  13552
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13552
ttccttcttt macagtcatt t                                               21


<210>  13553
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13553
gaactcaagt sagaaagaaa g                                               21


<210>  13554
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13554
ttagtgtcta kccctggtcg g                                               21


<210>  13555
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13555
ttttttttgt rtctagcaga c                                               21


<210>  13556
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13556
taatggaaag ycttcgatat a                                               21


<210>  13557
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13557
actggtaacc stcaagaaga g                                               21


<210>  13558
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13558
aggtttctta yttctgtatt g                                               21


<210>  13559
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13559
ttgtggtatc rctgccaaag a                                               21


<210>  13560
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13560
agtctgttac kgccagtttt g                                               21


<210>  13561
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13561
tgaatgagag ktagtcatct g                                               21


<210>  13562
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13562
gggagagcaa rtggtttctc a                                               21


<210>  13563
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13563
tttgctcaaa ygaagaaaga g                                               21


<210>  13564
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13564
ataaagagct staaaatgtg c                                               21


<210>  13565
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13565
ctctggaacc stgtggcact g                                               21


<210>  13566
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13566
cacttccttt racgggttca c                                               21


<210>  13567
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13567
gggcagggca ygaacctatt g                                               21


<210>  13568
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13568
attcatcaca raagtaggaa g                                               21


<210>  13569
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13569
atttcaagac ygaacaggag t                                               21


<210>  13570
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13570
gattccctga ygactacagg c                                               21


<210>  13571
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13571
agtgtacagt kagcccttca t                                               21


<210>  13572
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13572
gatgtttcat ragctcccta t                                               21


<210>  13573
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13573
tgcaatgaat ktatagagga c                                               21


<210>  13574
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13574
ataaaatatc stgggaaaaa a                                               21


<210>  13575
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13575
gtttagtaac rtgtcattcc t                                               21


<210>  13576
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13576
ggcataaaga rgatgttgat t                                               21


<210>  13577
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13577
ccaatcgagg yttcaaacaa g                                               21


<210>  13578
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13578
aaaagtgtac yactggacga a                                               21


<210>  13579
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13579
ttccttgtgg ygctctcaga a                                               21


<210>  13580
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13580
ggcctacagg kgatgacatc t                                               21


<210>  13581
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13581
agtttagcag yactcaaggc a                                               21


<210>  13582
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13582
agacttactg sctgtgtgga g                                               21


<210>  13583
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13583
ctttctggat ygagatgcca c                                               21


<210>  13584
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13584
tgggcatttg raaaatcaac c                                               21


<210>  13585
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13585
aaccccttga yctttcactt t                                               21


<210>  13586
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13586
agaaaccatt kccatttctc t                                               21


<210>  13587
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13587
agctgaagag rcttccctgg a                                               21


<210>  13588
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13588
tatcatgagg sagtaggaac t                                               21


<210>  13589
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13589
atcctttgat mctgatgcta g                                               21


<210>  13590
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13590
ataaagaaat raaactggac a                                               21


<210>  13591
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13591
tactggttat rttcatttat t                                               21


<210>  13592
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13592
tctcaaaaga wggtaaaaga a                                               21


<210>  13593
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13593
ctgacattat rattgcaaca a                                               21


<210>  13594
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13594
gattttccca rgggattcta t                                               21


<210>  13595
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13595
ttagttgctg ktgtactcaa t                                               21


<210>  13596
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13596
ttcataaagc yttctgatga g                                               21


<210>  13597
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13597
aaaagagata ygcaagaaac c                                               21


<210>  13598
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13598
ggtccaatta ycgactactt g                                               21


<210>  13599
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13599
gggaaaaaat sccggggcat t                                               21


<210>  13600
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13600
acgtgacata rgtgtgaaat a                                               21


<210>  13601
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13601
aaactctcaa yatctactaa g                                               21


<210>  13602
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13602
tagtgggtga ygtgtaaaca c                                               21


<210>  13603
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13603
accctgtgta maaatctgtc a                                               21


<210>  13604
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13604
ttgtatcctg rgaggtatgg a                                               21


<210>  13605
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13605
acttttcaga rtttagcaag c                                               21


<210>  13606
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13606
gaatatatta yaagcactgc t                                               21


<210>  13607
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13607
cgtgtcttta ragttacaat t                                               21


<210>  13608
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13608
cagacaataa rtggcaaaga a                                               21


<210>  13609
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13609
tttgccaagt rctttgagga t                                               21


<210>  13610
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13610
gtgggtccta raaaagccga g                                               21


<210>  13611
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13611
atattttaaa rcttatttac c                                               21


<210>  13612
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13612
gatatttatc kacttgaaag a                                               21


<210>  13613
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13613
tcagtagcat raaaagagct g                                               21


<210>  13614
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13614
aagttatagt ratccatata a                                               21


<210>  13615
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13615
atgtgcaaac ytagtcttat a                                               21


<210>  13616
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13616
acctcctact yttgaacttg c                                               21


<210>  13617
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13617
tagatccaaa rtcagggccc c                                               21


<210>  13618
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13618
ctctgctccc magtgaattc a                                               21


<210>  13619
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13619
agtatgctac rtacccacaa t                                               21


<210>  13620
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13620
tgaataaaga kcaaaaaatg t                                               21


<210>  13621
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13621
ctattaactc yaaggagaaa c                                               21


<210>  13622
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13622
cttatcagct rtgttgcttt a                                               21


<210>  13623
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13623
tggagttgga ygagaatctt t                                               21


<210>  13624
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13624
tatggcccag rggtctcttg c                                               21


<210>  13625
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13625
ctcctgcagg yggctccttt t                                               21


<210>  13626
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13626
gagaatcagt rctgcctgca c                                               21


<210>  13627
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13627
atctcctata katcaggaca g                                               21


<210>  13628
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13628
ttcatcctga ygccctgtag c                                               21


<210>  13629
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13629
atgtgaaaac rttgggctcc t                                               21


<210>  13630
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13630
tacaattcac wtgggtaccc t                                               21


<210>  13631
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13631
ttctcctttt rgtctgaggc a                                               21


<210>  13632
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13632
atgaaaacca yctggatata g                                               21


<210>  13633
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13633
gtggtcctca raaaatagga c                                               21


<210>  13634
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13634
ccaacacccc raagagaatg a                                               21


<210>  13635
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13635
ccttttgcta ygcctgagag g                                               21


<210>  13636
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13636
caaagccaca rtgtaatggt a                                               21


<210>  13637
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13637
atcattttac raggcatttc g                                               21


<210>  13638
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13638
caaaagtgac rgattctttc c                                               21


<210>  13639
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13639
tgtttctgaa raataatctg g                                               21


<210>  13640
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13640
aaaatggttg raaaagtcac g                                               21


<210>  13641
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13641
acaaactgaa raatgtcaca t                                               21


<210>  13642
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13642
taaggagtac yacactagca t                                               21


<210>  13643
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13643
ttctacagtc racatgtcat t                                               21


<210>  13644
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13644
accagctgtg kaagagtggc t                                               21


<210>  13645
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13645
catctcagga rcagagttta a                                               21


<210>  13646
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13646
tttgtgtgtt kgaattaatg a                                               21


<210>  13647
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13647
ggtagtgtgt ktattttact g                                               21


<210>  13648
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13648
gttgctaggg ygtggcagga c                                               21


<210>  13649
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13649
gtatgtctgc rgggagcaca g                                               21


<210>  13650
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13650
aagtccttgg yatcaaggca t                                               21


<210>  13651
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13651
ttggacatca ygtcacgggc c                                               21


<210>  13652
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13652
cgtaggaata matcaacagg a                                               21


<210>  13653
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13653
cagagtcagc rccctgtagg c                                               21


<210>  13654
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13654
tctaatgcag magggaaaca a                                               21


<210>  13655
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13655
tagcagagga mtcccagtga c                                               21


<210>  13656
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13656
agtaatccta macatttgta t                                               21


<210>  13657
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13657
gctttctcac ycttaacagg t                                               21


<210>  13658
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13658
agacaccgcc rtgagcccaa t                                               21


<210>  13659
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13659
taattttaca rgtgagcatc c                                               21


<210>  13660
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13660
ccaggaacac rgcattctca a                                               21


<210>  13661
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13661
aaggctgtga ygttgccact c                                               21


<210>  13662
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13662
cagttaggca waataagaga a                                               21


<210>  13663
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13663
aatgtgttaa mcagatgaat a                                               21


<210>  13664
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13664
catatccctc rggcgtcctt t                                               21


<210>  13665
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13665
tggctactcc rtccttctca g                                               21


<210>  13666
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13666
gaacatcctg kctacagcat g                                               21


<210>  13667
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13667
tcagggccat rtttactcac t                                               21


<210>  13668
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13668
tagtaagtag rgtatgttct g                                               21


<210>  13669
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13669
ttgtgtccgt sggaaagctg g                                               21


<210>  13670
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13670
aaggacttca rcccataatc c                                               21


<210>  13671
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13671
ccatggtaag kttgatggtg c                                               21


<210>  13672
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13672
acccaggaag sgctgagcca c                                               21


<210>  13673
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13673
gctggccagg ygggagctga c                                               21


<210>  13674
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13674
cagaaatgac magacaagaa a                                               21


<210>  13675
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13675
tcagaatacc yatatgcaac a                                               21


<210>  13676
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13676
cccctaaaca rcagtgccct a                                               21


<210>  13677
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13677
caacaaccct rtagggtagg c                                               21


<210>  13678
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13678
ggaatgactg wccgtgatga g                                               21


<210>  13679
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13679
tcaggtttaa sattagagag g                                               21


<210>  13680
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13680
gctacaatga mattgcgctt g                                               21


<210>  13681
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13681
cacaaaggcg rtatgttcaa c                                               21


<210>  13682
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13682
ctggaactaa yggctaaaaa a                                               21


<210>  13683
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13683
tttagctata sagcaatttt a                                               21


<210>  13684
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13684
catgggagaa ytggccttgg c                                               21


<210>  13685
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13685
aaaactgccc rattgtgata t                                               21


<210>  13686
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13686
tccaggaggc rtgtgcttgt t                                               21


<210>  13687
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13687
aaagctctag kacaaaaata a                                               21


<210>  13688
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13688
gtgattatgg rgaaaagttc a                                               21


<210>  13689
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13689
tggagaagca racacccatg t                                               21


<210>  13690
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13690
acatacacaa rcttggggcc c                                               21


<210>  13691
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13691
taacatccac kacccagact t                                               21


<210>  13692
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13692
agtcatgaac rtcaagggca g                                               21


<210>  13693
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13693
agcaagaagc rgacgagctg t                                               21


<210>  13694
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13694
gcctggaaaa yggactctgt c                                               21


<210>  13695
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13695
agtgatgatg stgaggccag t                                               21


<210>  13696
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13696
ctgaatctga raatgcctga g                                               21


<210>  13697
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13697
ttgattgatt rggttttttt c                                               21


<210>  13698
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13698
tctaggcaga rctttggtct a                                               21


<210>  13699
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13699
taatagttct ygaggcttca t                                               21


<210>  13700
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13700
caaaaagaat kttgataggc a                                               21


<210>  13701
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13701
tcaatgagat ragtcttttt a                                               21


<210>  13702
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13702
ctcgagggct ktctatggta t                                               21


<210>  13703
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13703
gacatatttc ygaacccagg a                                               21


<210>  13704
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13704
cctaaaacca yctgatcttt g                                               21


<210>  13705
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13705
attcaacagt ygaccccagc t                                               21


<210>  13706
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13706
ctaattttgg mgataagcag c                                               21


<210>  13707
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13707
atcaaagtgg rtggccctta t                                               21


<210>  13708
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13708
acaggaattc rtggcccaat t                                               21


<210>  13709
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13709
aataaagaaa yttactcgct g                                               21


<210>  13710
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13710
aaacccttca ygtgggagct g                                               21


<210>  13711
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13711
gcttaattaa ytacatcctg a                                               21


<210>  13712
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13712
tctattccat ytccgaatgg g                                               21


<210>  13713
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13713
agcctaaaac raacagcatt c                                               21


<210>  13714
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13714
cgatcaatgc rataggccgc c                                               21


<210>  13715
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13715
ccactctgga ygcaggcgag a                                               21


<210>  13716
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13716
tctgaagcca ygtactgctg g                                               21


<210>  13717
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13717
gagctacctc rataacaggg g                                               21


<210>  13718
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13718
caaatgacac rtctcttatg a                                               21


<210>  13719
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13719
tatcaagttc mgaagttttc c                                               21


<210>  13720
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13720
atttattcag ytctgtgtag g                                               21


<210>  13721
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13721
gtggttcaaa yaatgctgtg g                                               21


<210>  13722
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13722
gcactgtaca ragattggtt t                                               21


<210>  13723
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13723
tgattctgct yaatttagaa t                                               21


<210>  13724
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13724
tggcacccag rgagaggcaa c                                               21


<210>  13725
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13725
aaatgtgagg raaaaaatac g                                               21


<210>  13726
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13726
agtcacttac ktttcctagg g                                               21


<210>  13727
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13727
aacaggccta yattctagtc t                                               21


<210>  13728
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13728
gacccgggag ragcaatttc a                                               21


<210>  13729
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13729
atctctgaat kttgtgcgta t                                               21


<210>  13730
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13730
tcattactta ygtttttata g                                               21


<210>  13731
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13731
ttggcaacag ktcatacaat a                                               21


<210>  13732
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13732
tttacactca rgagagctgg g                                               21


<210>  13733
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13733
ctatattttc yagcactgat c                                               21


<210>  13734
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13734
atggttatac rtgcacatat g                                               21


<210>  13735
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13735
tctcagggcc rtcgattatt t                                               21


<210>  13736
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13736
taaaaagggg stcggagctc t                                               21


<210>  13737
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13737
tcagctttta ygctctgtga c                                               21


<210>  13738
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13738
gctgctgtga sccagtcatt g                                               21


<210>  13739
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13739
aaagggcgct wctagtccaa a                                               21


<210>  13740
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13740
cacatgatca rtcctggtct t                                               21


<210>  13741
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13741
tgtttactga magccaatta t                                               21


<210>  13742
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13742
cacgctggtg rcgactgaaa c                                               21


<210>  13743
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13743
aaagggaccc rtcgctttcc a                                               21


<210>  13744
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13744
gggtgtcgaa rctagtcttc t                                               21


<210>  13745
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13745
ctgcactgtc rgagcccttg g                                               21


<210>  13746
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13746
ccttccatga wgatatctga a                                               21


<210>  13747
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13747
ccattagagg sgtccaatgc t                                               21


<210>  13748
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13748
gaatcctctt yaggaatgtt g                                               21


<210>  13749
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13749
acttgctgca watatgtaga g                                               21


<210>  13750
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13750
actttttaaa wtcatgcatt t                                               21


<210>  13751
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13751
ggggaattag yccacagggt t                                               21


<210>  13752
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13752
ttgggttaca yggcctgaaa g                                               21


<210>  13753
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13753
ctacaatttc wgggtgtttt t                                               21


<210>  13754
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13754
ttagaccaaa ycaagacagt t                                               21


<210>  13755
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13755
aaaatgctaa yttttaggct t                                               21


<210>  13756
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13756
tgactgacaa yattagcaga g                                               21


<210>  13757
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13757
ctgaggccca ytcagaaaac c                                               21


<210>  13758
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13758
acatctcaga maaccaggaa a                                               21


<210>  13759
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13759
tataatttca rtaactccca g                                               21


<210>  13760
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13760
cttgtatcaa yggaaaaatt t                                               21


<210>  13761
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13761
tggaatttaa mactgccaaa a                                               21


<210>  13762
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13762
actaccggcc rtgatttggg g                                               21


<210>  13763
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13763
cattctgatc rgcctttgct t                                               21


<210>  13764
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13764
cagtgcttcc ygggctcacc t                                               21


<210>  13765
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13765
atcagacata yagctcacaa a                                               21


<210>  13766
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13766
atgatcttcc rctccggctt t                                               21


<210>  13767
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13767
gatgacttcg wtttctgctc c                                               21


<210>  13768
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13768
gcaaggtcag rcgggagcat g                                               21


<210>  13769
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13769
ccgctgagca kgggtcccca g                                               21


<210>  13770
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13770
actcaaaaga yaccgtatgt c                                               21


<210>  13771
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13771
cagaactgct mgtgtaaccc a                                               21


<210>  13772
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13772
ataccctgat maaattgtta c                                               21


<210>  13773
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13773
aaggagaaac racaggacga c                                               21


<210>  13774
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13774
tgaagcattt mgggatctta g                                               21


<210>  13775
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13775
acagatggct stcaaggtcg c                                               21


<210>  13776
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13776
cctgaaggaa ygtaaaacca t                                               21


<210>  13777
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13777
ccaaattcca yactctaaat a                                               21


<210>  13778
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13778
acttttttct yatctgtatt c                                               21


<210>  13779
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13779
gagctactgg rctgaggttc g                                               21


<210>  13780
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13780
atgtgctgct rttaaacatt a                                               21


<210>  13781
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13781
ataatacaag racacttgga c                                               21


<210>  13782
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13782
ttggaattag rctgaggagc t                                               21


<210>  13783
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13783
tttactctgc ratactcagt a                                               21


<210>  13784
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13784
gactaaccca ygccttaagg a                                               21


<210>  13785
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13785
caaagggaaa rtgaaagcat t                                               21


<210>  13786
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13786
acatgcttat rgttattctt a                                               21


<210>  13787
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13787
acagtctggt wgaaagcttt t                                               21


<210>  13788
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13788
tcataggaat rttgtgagct c                                               21


<210>  13789
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13789
ctttggagaa stacgagttt t                                               21


<210>  13790
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13790
aaaatgttcc rccaaggcct c                                               21


<210>  13791
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13791
agacactctc yccaagatgc t                                               21


<210>  13792
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13792
aattagagta satcagtatt t                                               21


<210>  13793
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13793
agggctttct rtttcagatc a                                               21


<210>  13794
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13794
catatgttcc rgaggtgagg a                                               21


<210>  13795
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13795
gcaatccaaa sagaaaaggg a                                               21


<210>  13796
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13796
ctatattccc ragtctcctt t                                               21


<210>  13797
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13797
atgtagggca ygtggcccca g                                               21


<210>  13798
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13798
caaagcccca rtttgcccag c                                               21


<210>  13799
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13799
ctcaccttta yaggcttctc a                                               21


<210>  13800
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13800
gcaggactaa rcctgggcct t                                               21


<210>  13801
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13801
ctgaccttca ycaagagcgc c                                               21


<210>  13802
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13802
tttcgagtac ratccagaga a                                               21


<210>  13803
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13803
tcaggaatga mgtacatata t                                               21


<210>  13804
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13804
cagttacttg rgaaatgttt g                                               21


<210>  13805
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13805
tctacttagc kataaaacat g                                               21


<210>  13806
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13806
tgacaaatag yaggtggtca a                                               21


<210>  13807
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13807
cctatgaagg yctcattaac a                                               21


<210>  13808
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13808
ccattgtgca yggccttgag t                                               21


<210>  13809
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13809
acaagttcct rtactgctcg g                                               21


<210>  13810
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13810
actgactttg ygctttttag g                                               21


<210>  13811
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13811
ttttcccata yttttatata c                                               21


<210>  13812
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13812
ttatctgaaa stacgccttt g                                               21


<210>  13813
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13813
atctcacaca rtgaaagagg g                                               21


<210>  13814
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13814
aaggcaaaca wggtgttatt a                                               21


<210>  13815
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13815
tttgaatgta raacggccta g                                               21


<210>  13816
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13816
acatgaaatc rttttcttag g                                               21


<210>  13817
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13817
ttcctggtag rcaagccaat c                                               21


<210>  13818
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13818
atagatataa statggaaaa c                                               21


<210>  13819
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13819
agaagtttct kgaacccctg g                                               21


<210>  13820
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13820
tgtgagcaag sgttttcagg t                                               21


<210>  13821
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13821
tagagcagca rtgagcactt g                                               21


<210>  13822
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13822
tgaaaaggta sagaaaatgt c                                               21


<210>  13823
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13823
ttagggaaag rtgtgacatg a                                               21


<210>  13824
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13824
aatacgtgct scaaaagaaa a                                               21


<210>  13825
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13825
gggtggcacc rtgccccatg c                                               21


<210>  13826
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13826
tgcctgatgc rgtgcagtac t                                               21


<210>  13827
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13827
cattttcctg mtccattttc t                                               21


<210>  13828
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13828
gcagagccat mttacaattt a                                               21


<210>  13829
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13829
atcttactta watccatcta g                                               21


<210>  13830
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13830
gtaataaggt matttagatt t                                               21


<210>  13831
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13831
ttgatgtctc raattttttt c                                               21


<210>  13832
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13832
gggcagcaag wggatgattc c                                               21


<210>  13833
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13833
ttgttaacac raagcaaaaa g                                               21


<210>  13834
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13834
gtcaagagca kgtatcctta g                                               21


<210>  13835
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13835
tcctaacctt sccttgataa g                                               21


<210>  13836
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13836
tggctaaggg ytacatttga t                                               21


<210>  13837
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13837
aaaatacata ygaaaggtac a                                               21


<210>  13838
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13838
tcccctagga scgcacctcg t                                               21


<210>  13839
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13839
aagttttgaa yagaatctaa g                                               21


<210>  13840
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13840
gcgactcctt ygattccctc c                                               21


<210>  13841
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13841
actttatagc rctggcaaaa c                                               21


<210>  13842
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13842
atactagaat ratcatcagc t                                               21


<210>  13843
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13843
ctgcttagac raacccatgt a                                               21


<210>  13844
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13844
gaacactgga yggcaagata c                                               21


<210>  13845
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13845
aaaggttctc sgccaatttc a                                               21


<210>  13846
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13846
tctgtcagca wccataataa a                                               21


<210>  13847
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13847
agctaatcaa wgggcttgaa g                                               21


<210>  13848
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13848
acatggcttt ygacactcgc c                                               21


<210>  13849
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13849
gtcagttccc rtaataacat a                                               21


<210>  13850
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13850
gtaaaatttg raactgggtt c                                               21


<210>  13851
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13851
cctctagcac wgtactcatt g                                               21


<210>  13852
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13852
cagagcaagg maagtgttga t                                               21


<210>  13853
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13853
agattcttgg ktcttttagg c                                               21


<210>  13854
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13854
agattgagag rccattgccc c                                               21


<210>  13855
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13855
ttgttgaaac rtaatgagcg t                                               21


<210>  13856
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13856
cccaaaaagt raacaggtgt g                                               21


<210>  13857
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13857
tgggccaaag rtagtgcctg g                                               21


<210>  13858
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13858
ttgggctgtc rtctttgtag c                                               21


<210>  13859
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13859
tggaacactg sgatgcattt a                                               21


<210>  13860
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13860
atactcatta yaaatactct c                                               21


<210>  13861
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13861
aatattcatg yaattgctgg t                                               21


<210>  13862
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13862
cagcttagat ycaacatgcc c                                               21


<210>  13863
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13863
tctaagaaac rggatatacg t                                               21


<210>  13864
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13864
ggtggctgac racccatagt g                                               21


<210>  13865
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13865
tctcaggatc kctggttcgt g                                               21


<210>  13866
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13866
aaaatgtatc mtttgacatg g                                               21


<210>  13867
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13867
tgaagatggt ygtgcaacct t                                               21


<210>  13868
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13868
gagtttagtg yccttcttgg g                                               21


<210>  13869
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13869
aatacctaaa wgtcaacaca c                                               21


<210>  13870
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13870
tagtagtatg ytctgcaatg c                                               21


<210>  13871
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13871
ttttgtagtt kataacatat t                                               21


<210>  13872
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13872
catttttaaa rctaggcatt t                                               21


<210>  13873
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13873
actaaaaaga wggcatggac a                                               21


<210>  13874
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13874
ttaacagtca ktgcagagtt t                                               21


<210>  13875
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13875
tacatttcta yttaaactca a                                               21


<210>  13876
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13876
taacttcaat ytgtgaaagc c                                               21


<210>  13877
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13877
ctttcagcca yagcacattt a                                               21


<210>  13878
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13878
ttataaatgc rtacgccaga g                                               21


<210>  13879
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13879
ctcaaaggca ygaaaataca g                                               21


<210>  13880
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13880
atcaatagaa mccagtggca t                                               21


<210>  13881
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13881
tgatttggag racagacatt c                                               21


<210>  13882
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13882
ccctgtagtc stattagaat a                                               21


<210>  13883
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13883
actcagttat yctctggggc t                                               21


<210>  13884
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13884
cagcaccctt sattcatcag c                                               21


<210>  13885
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13885
acacttactt rttcagacaa c                                               21


<210>  13886
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13886
caagctaaca rtggagactg c                                               21


<210>  13887
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13887
ccttaaaggg rtgcggtttt t                                               21


<210>  13888
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13888
ttgttcatag ygcagttggt a                                               21


<210>  13889
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13889
agaataatct ktctgccatt a                                               21


<210>  13890
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13890
agcaaaatac rtactcaaag t                                               21


<210>  13891
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13891
agaaagattg sacctgcctg g                                               21


<210>  13892
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13892
aggtgagggc yactgtgcag g                                               21


<210>  13893
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13893
tggctttctt yagtcagagg t                                               21


<210>  13894
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13894
tcgcgagtcc ygcatggcac a                                               21


<210>  13895
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13895
ttaaaaagcc rtgttcctgc c                                               21


<210>  13896
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13896
ctgtgtgtca sttgctgcgt g                                               21


<210>  13897
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13897
agcgggaacc raaagcctgg c                                               21


<210>  13898
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13898
ggtccggcca ytgcaagttt t                                               21


<210>  13899
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13899
tcccagcttc kgagccaatg c                                               21


<210>  13900
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13900
tatatgcctc yactcttgag g                                               21


<210>  13901
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13901
ttccccacct ytgacctgct g                                               21


<210>  13902
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13902
tacatgctta ytgtaaatga c                                               21


<210>  13903
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13903
ttgtacgagg rgaaagaaaa a                                               21


<210>  13904
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13904
aaatcgtcct ygcccaccct t                                               21


<210>  13905
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13905
ctaatttact rggaggcttc c                                               21


<210>  13906
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13906
agtactcaac rtctctcaaa t                                               21


<210>  13907
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13907
ggaaatgctt ygtcttcgtg g                                               21


<210>  13908
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13908
ataccacaaa mccaggtctc c                                               21


<210>  13909
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13909
gaccacgcct ycggtgctct c                                               21


<210>  13910
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13910
catctgccct sacccttggc c                                               21


<210>  13911
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13911
cattcattgg stcctggcca t                                               21


<210>  13912
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13912
ttaaagtcac rcagccaatg g                                               21


<210>  13913
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13913
agccagaatg ygcagggcat a                                               21


<210>  13914
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13914
aggttggtaa yggtgacata t                                               21


<210>  13915
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13915
gactgcacca rccaagtccc a                                               21


<210>  13916
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13916
cttctaccca racaagcagg t                                               21


<210>  13917
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13917
aaagacattt mtccccaggg g                                               21


<210>  13918
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13918
cttctgttca sgcaactcca a                                               21


<210>  13919
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13919
atgaggcagc wtcacctgtg c                                               21


<210>  13920
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13920
ttagcatcaa wttagtaagc a                                               21


<210>  13921
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13921
aatttgcttg ygaatcactt g                                               21


<210>  13922
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13922
aattgagtcc yttggtgtga a                                               21


<210>  13923
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13923
agctggtggc yagtgcaaag g                                               21


<210>  13924
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13924
ggcgtggtgc raggtactcc t                                               21


<210>  13925
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13925
tttcatgatg ygaaaaatga t                                               21


<210>  13926
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13926
agaagtcagg yagaagcaat g                                               21


<210>  13927
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13927
aggagaacca sgagtatgga g                                               21


<210>  13928
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13928
agcagtatcc yttctagttc t                                               21


<210>  13929
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13929
agaaggaaac ractctgacc a                                               21


<210>  13930
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13930
catagcttct yaaaatatcg a                                               21


<210>  13931
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13931
ttcatgctgc ytccacaatt t                                               21


<210>  13932
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13932
cacattctaa maccacatcc t                                               21


<210>  13933
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13933
gagttagctc rgaatattca g                                               21


<210>  13934
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13934
tgcctactgt rtacctatga t                                               21


<210>  13935
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13935
agtggcacca raattctcaa a                                               21


<210>  13936
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13936
agaggtaact stgaagtgaa a                                               21


<210>  13937
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13937
gactctatta kgcattcatg t                                               21


<210>  13938
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13938
tccaagtcat ytgaaaaaac a                                               21


<210>  13939
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13939
aaatgttctc rtaactttgc a                                               21


<210>  13940
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13940
cttttcagaa mtctggaatg a                                               21


<210>  13941
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13941
ccatttttac rttagccttg a                                               21


<210>  13942
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13942
gtcatatcaa rtttttagag c                                               21


<210>  13943
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13943
tattacaggc rgaaaatagc c                                               21


<210>  13944
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13944
atctgtggag rgatgatgac c                                               21


<210>  13945
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13945
atggatacta waggataaac a                                               21


<210>  13946
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13946
tttaaattat staggcctca t                                               21


<210>  13947
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13947
aaattaacca wcttgccatc t                                               21


<210>  13948
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13948
atctcaggta yatcgattta c                                               21


<210>  13949
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13949
ctacgtggca yggtcaaaaa c                                               21


<210>  13950
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13950
gagagaccag raaaatagag g                                               21


<210>  13951
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13951
aaagaattac rgattcctaa g                                               21


<210>  13952
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13952
atacattgta mctcataaga g                                               21


<210>  13953
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13953
tttgcctctc rgttgaaacc t                                               21


<210>  13954
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13954
ataacagtgt ycatggtatg t                                               21


<210>  13955
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13955
aagattagcc ragaaggaag a                                               21


<210>  13956
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13956
atcttggaaa mattatcgat c                                               21


<210>  13957
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13957
ccaaggcaat ycatcacctc t                                               21


<210>  13958
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13958
ttgtacactt ygtaggttag c                                               21


<210>  13959
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13959
aagacgtgac ygaacaattt t                                               21


<210>  13960
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13960
ctgaacccta ygccacaaac a                                               21


<210>  13961
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13961
atgcttacac mctggagtct t                                               21


<210>  13962
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13962
aaacctggaa sctttggaaa c                                               21


<210>  13963
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13963
cccgccttgt yacacgcctt a                                               21


<210>  13964
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13964
acaacatcac yggtatggga g                                               21


<210>  13965
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13965
cgtgaaatcc sctgcagtga a                                               21


<210>  13966
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13966
ggacagcgga ygcttgagga g                                               21


<210>  13967
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13967
acttttactc rgctgctaac t                                               21


<210>  13968
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13968
tctcctgctt yttcacatca c                                               21


<210>  13969
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13969
cctctgggct yggattgtac c                                               21


<210>  13970
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13970
gcaattccat yctcctttcc a                                               21


<210>  13971
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13971
agggaataat rtccaaaaag t                                               21


<210>  13972
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13972
tgtaatatct rgctatccat t                                               21


<210>  13973
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13973
cctgagatac mttggcctca g                                               21


<210>  13974
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13974
caagctttat ytcttgagtt g                                               21


<210>  13975
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13975
tggaatcaga ytgtgcaagc t                                               21


<210>  13976
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13976
atggctctac scttggcttt c                                               21


<210>  13977
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13977
ttagagactc rtatgaaaaa g                                               21


<210>  13978
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13978
agaagtactc rccagaggcc t                                               21


<210>  13979
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13979
cttctataac rcaggaacta t                                               21


<210>  13980
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13980
tccacaactg wttttggaaa g                                               21


<210>  13981
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13981
aaatgagtgg ygtttataac a                                               21


<210>  13982
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13982
ttctctaatc ktccttttac a                                               21


<210>  13983
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13983
gacttcacag yagtaagaag g                                               21


<210>  13984
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13984
gatgaatcaa ygactaagag c                                               21


<210>  13985
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13985
tctttattga ytaccttgtg c                                               21


<210>  13986
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13986
tgattttaca ytggagcaca g                                               21


<210>  13987
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13987
tgctatgaac rctgtctcca c                                               21


<210>  13988
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13988
ctccaggctt yctgcccctg t                                               21


<210>  13989
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13989
tgtaactatg raacaatgat a                                               21


<210>  13990
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13990
caggttagga yacagatgag g                                               21


<210>  13991
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13991
gttgcaggca sttttgaaag a                                               21


<210>  13992
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13992
tccggttgca ytctcatgtt c                                               21


<210>  13993
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13993
tggtttgagc stctcttggg t                                               21


<210>  13994
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13994
aagccatgac rctttgcaga g                                               21


<210>  13995
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13995
acaaagccac maacttctat c                                               21


<210>  13996
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13996
cagtcagggt rtttttacag t                                               21


<210>  13997
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13997
aaagtgctca ygtatatatg t                                               21


<210>  13998
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13998
gatgatccta saggaactgc a                                               21


<210>  13999
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  13999
caggaaagct rggaataaaa t                                               21


<210>  14000
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14000
aacttcctac rctgtctaca g                                               21


<210>  14001
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14001
tccttttcta yatgcccttc t                                               21


<210>  14002
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14002
atagaacata wcctaggcca t                                               21


<210>  14003
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14003
ctcatctact yagccctgcc t                                               21


<210>  14004
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14004
tattcttcca yccaggagat g                                               21


<210>  14005
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14005
aatgtcaata rttggttaaa a                                               21


<210>  14006
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14006
aacaccaaga yctatagtta t                                               21


<210>  14007
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14007
cgtcgtacga yctgatgaaa a                                               21


<210>  14008
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14008
tgataagttc ygtgttctgt c                                               21


<210>  14009
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14009
actcttgtaa ygatgtatta g                                               21


<210>  14010
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14010
aggcttaaag yggttgagtt a                                               21


<210>  14011
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14011
ggccagctgc ytggggaccc t                                               21


<210>  14012
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14012
gtactgttaa maactatatc c                                               21


<210>  14013
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14013
acattgaaat ytgcaagaca t                                               21


<210>  14014
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14014
caattaatag yttggccacc a                                               21


<210>  14015
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14015
ttagtatata ygttttgcct a                                               21


<210>  14016
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14016
tcttttcata wtttttccta c                                               21


<210>  14017
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14017
aatattaaag ygtaaaaaat a                                               21


<210>  14018
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14018
ccgactctct kttgcattta t                                               21


<210>  14019
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14019
acctttgcga mctaaagtag t                                               21


<210>  14020
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14020
gctttgaaag satttctacc a                                               21


<210>  14021
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14021
tcctgtactc yttgaacatt t                                               21


<210>  14022
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14022
tacatgtgga rtcaataaag c                                               21


<210>  14023
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14023
gaaactagaa kcactgaaca a                                               21


<210>  14024
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14024
agattctgtt ycaaggttag a                                               21


<210>  14025
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14025
ggcttccttt scaatccaac c                                               21


<210>  14026
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14026
catgattgtc rattatgatt a                                               21


<210>  14027
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14027
tgggcatcaa rtctacatta t                                               21


<210>  14028
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14028
tgcatgaaga ytgactctta a                                               21


<210>  14029
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14029
tgaccaaaga yggatgttct c                                               21


<210>  14030
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14030
ggcactgctg yagttctcct g                                               21


<210>  14031
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14031
agcaaagact yagggaagaa g                                               21


<210>  14032
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14032
tccctaggtg wtctaaaaag a                                               21


<210>  14033
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14033
ctgacttaaa ratgagttag t                                               21


<210>  14034
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14034
tcgaaagtat rcccgcaggt c                                               21


<210>  14035
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14035
tacacatgca raggggccaa c                                               21


<210>  14036
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14036
aacagcagtg ytcaatgttg g                                               21


<210>  14037
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14037
acaggcattt rgcagcacac a                                               21


<210>  14038
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14038
tctagtgttc rgttcaaata c                                               21


<210>  14039
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14039
tgaccatata ycctgaggct g                                               21


<210>  14040
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14040
ggtgactctc ragactccct t                                               21


<210>  14041
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14041
cttggcttca ygttcctaag c                                               21


<210>  14042
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14042
caaccatcaa yggcagcagt c                                               21


<210>  14043
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14043
tcttcacaac staatagctc t                                               21


<210>  14044
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14044
gacatccact sgtttaaaaa t                                               21


<210>  14045
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14045
ggtttgagga wgtttttggc c                                               21


<210>  14046
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14046
tcatgctcag ygtttctttt a                                               21


<210>  14047
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14047
tggagattaa ytgggcatcc c                                               21


<210>  14048
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14048
gattgtgcct sttatcccat g                                               21


<210>  14049
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14049
agggaaacac ygtggcaagg a                                               21


<210>  14050
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14050
aggtgttgca yattctgttc a                                               21


<210>  14051
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14051
atgagctact raaaaaaatc c                                               21


<210>  14052
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14052
gtttaaagac yaaataagta c                                               21


<210>  14053
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14053
tttgcacata ytgatgatcc c                                               21


<210>  14054
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14054
tcaaaatatt ytttaaactg c                                               21


<210>  14055
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14055
gaatcaagga yaaaaggtca a                                               21


<210>  14056
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14056
aacaattctt rtatgctgaa a                                               21


<210>  14057
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14057
agaattttaa yggaaacact t                                               21


<210>  14058
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14058
aaaggcaaca matatccaat c                                               21


<210>  14059
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14059
gaagaaaatg scatctccca c                                               21


<210>  14060
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14060
caaatgttca yctttcacca t                                               21


<210>  14061
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14061
aaaaattcaa matcatgatc a                                               21


<210>  14062
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14062
ttttcgcctc rtcccaacct g                                               21


<210>  14063
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14063
aatgtgtatg wccttagaaa t                                               21


<210>  14064
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14064
gatcctcata ktttaaaagc t                                               21


<210>  14065
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14065
ggcttccaaa stttattaca a                                               21


<210>  14066
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14066
tctagaactg ragtacaaca g                                               21


<210>  14067
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14067
catcactttg mcacagtgtt c                                               21


<210>  14068
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14068
atctgtgctt wtgttacgaa t                                               21


<210>  14069
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14069
gctataggtt kctctttctc a                                               21


<210>  14070
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14070
agacagcaca ygtcgagaga a                                               21


<210>  14071
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14071
gagttagcaa yggtcagaac a                                               21


<210>  14072
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14072
gaagcctcct ygggaaacat t                                               21


<210>  14073
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14073
cctgagtgcc rctcccattt g                                               21


<210>  14074
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14074
aaaaatctct rctaaggctc a                                               21


<210>  14075
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14075
gagctgtcag ygccatgggt t                                               21


<210>  14076
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14076
tggggcagga wgggctaagt g                                               21


<210>  14077
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14077
cagttcctgt rggtttctca t                                               21


<210>  14078
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14078
cttttgtaaa ytgaaaggcc a                                               21


<210>  14079
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14079
aagaagttat saagtaaacc g                                               21


<210>  14080
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14080
acattcacca watcatcttt g                                               21


<210>  14081
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14081
gaaataagct matcttctat g                                               21


<210>  14082
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14082
actctcttag ygctattttt a                                               21


<210>  14083
<211>  21
<212>  DNA
<213>  Homo sapiens

<400>  14083
aaaagggaga ragatagtgg g                                               21
